|   |
29 | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | Q | P | P | E | I | H | A | G | S | W | V | L | M | D | Y | T | T | G | Q | I | L | T | A | G | N | E | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | Q | R | N | P | A | S | L | T | K | L | M | T | G | Y | V | V | D | R | A | I | D | S | H | R | I | T | P | D | D | I | V | T | V | G |
Query Conservation |   |
  |   |   |   |   |
|   |
|   |
|
|
|
|   |
|   |   |
|
|   |
|
|   |   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |   |   |
|
|
|   | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   | . |
Template Sequence |   |
G | G | A | K | Y | S | E | G | V | Y | A | V | A | L | N | P | Q | T | G | A | V | L | S | M | S | G | L | K | H | D | L | K | T | G | E | L | T | P | D | S | L | G | T | V | T | N | V | F | V | P | G | S | V | V | K | A | A | T | I | S | S | G | W | E | . |
. |
. |
N | G | V | L | S | G | N | Q | T | L | T | D | . |
Template Known Secondary structure |   |
S | T | T | T | T |
|
|  |  |  |  |  |  |  |
| T | T | T |
| B |  |  |  |  |  |  |  |  |  |
| T | T | T |
|
|  |  |  |
| T | T |  |  |  |  |
|
| B |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  |  | . | . | . | T | T | S |
|
| S | S |
|
|  |  |  | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | |
|
|
. | 400 | . | . | . | . | . | . | . | . | . | 410 | |
  |
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | D | A | W | A | K | D | N | P | V | F | V | G | S | S | L | M | F | L | K | E | G | D | . |
. |
. |
. |
. |
R | V | S | V | R | D | L | S | R | G | L | I | V | D | S | G | N | D | A | C | V | A | L | A | D | Y | I | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | R | Q | F | V | E | M | M | N | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   | . | . | . | . | . |   |   |
|
|   |
|
|
|   |
|   |
|
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |
| . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|
|   |   |
|
|   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|
|   |   | . | . | . | . |
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
Q | P | I | V | F | Q | G | S | A | P | I | Y | S | W | Y | K | L | A | Y | G | S | F | P | I | T | A | V | E | A | L | E | Y | . |
. |
. |
. |
S | S | N | A | Y | V | V | Q | T | A | L | G | I | M | G | Q | T | Y | Q | P | N | M | F | V | G | T | S | N | L | E | S | A | M | G | K | L | R | S |
Template Known Secondary structure |   |
. | . | . | . | . | . |
|
| B |
| B | T | T | S |
|
| B |
|
| T | T | T | T | T | T |
| S |  |  |  |
|  |  |  |  |  |  |  | . | . | . | . | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| T | T | B |
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
411 | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | |
|
|
|
. | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | |
|
|
|
. | . | . | . | . | . | 200 | . | . | . | . | . | . | |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |
|  |  |  |  |  |  |  |  |  |  |  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
Y | A | E | K | L | H | L | K | D | T | H | F | E | T | V | H | G | L | D | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | H | S | S | A | Y | D | L | A | V | L | S | R | A | I | I | H | . |
. |
. |
. |
G | E | P | E | F | Y | H | M | Y | S | E | K | S | . |
Query Conservation |   |
  |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   | . | . | . | . |   |   |
|   |   |   |   |
|   |   |   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   | . | . | . | . | . |   |
|
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|
|
|   |
|   |
|   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |
|
Template Sequence |   |
T | F | G | E | Y | G | L | G | S | . |
. |
. |
. |
. |
A | T | G | I | D | L | P | D | E | S | T | G | L | V | P | K | E | Y | N | F | A | N | F | I | T | N | A | F | G | Q | F | D | N | Y | T | P | M | Q | L | A | Q | Y | V | A | T | I | A | N | N | G | V | R | L | A | P | H | I | V | E | G | I | Y | D | N | N | D |
Template Known Secondary structure |   |
 |  |  | T | T | T | T | T | S | . | . | . | . | . |
|
|
|
| S | S | S |
|
|
|
|
| B |
|
| S | S |
|
|  |  |  |  |  |  |  | T | T | T | S | S | S | B | B |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |
|
| B | S |  |  |  |  |  |  |  |
| T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
481 | . | . | . | . | . | . | . | . | |
|
|
|
|
490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
207 | . | . | 210 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
L | T | W | N | G | I | T | Q | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | R | N | G | L | L | W | D | K | T | M | N | V | D | G | L | K | T | G | H | T | S | G | A | G | F | N | L | I | A | S | A | V | D | G | Q | R |
Query Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |
|
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   | . | . | . | . |
|
|
|
|
|   |
|   |   |   |
|
Template Sequence |   |
K | G | G | L | G | E | L | I | Q | A | I | D | T | K | E | I | N | K | V | N | I | S | E | S | D | M | A | I | L | H | Q | G | F | Y | Q | V | S | H | G | T | S | P | L | T | T | G | R | A | F | S | D | G | A | T | V | S | I | S | G | K | T | G | T | N | T | . |
. |
. |
. |
N | A | V | A | Y | A | P | T | E | N | P |
Template Known Secondary structure |   |
T | S | S |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | T | T |
|
|
| G | G | G | T | T | T |
| S | S |
|
|  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |  |  |  | S | T | T | S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
556 | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | |
|
|
|
. | . | . | . | . | . | . | . | . | 630 | . |
  |
  |   |
253 | . | . | . | |
. | . | . | 260 | . | . | |
|
|
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
Predicted Secondary structure |   |
 |  |  |  | . |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
| . |
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | L | I | A | . |
V | V | M | G | A | D | . |
. |
. |
S | A | K | G | R | E | E | E | A | R | K | L | L | R | W | G | Q | Q | N | F |
Query Conservation |   |
  |   |
|   | . |
|
|
|
|   |   | . | . | . |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
Template Sequence |   |
Q | I | A | V | A | V | V | F | P | H | N | T | N | L | T | K | N | V | G | P | A | I | A | R | D | I | I | N | L | Y | N | Q | H | H |
Template Known Secondary structure |   |
|  |  |  |  |  |  |
| T | T |
|
|
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
644 | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . |
  |