Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	A	L	T	A	S	C	I	D	L	N	I	Q	G	N	G	A	Y	S	V	L	K	Q	L	A	T	I	A	L	Q	N	G	F	I	T	D	S	H	Q	F	L	Q	T	L	L	L	R	E	K	M	H	S	T	G	F	G	S	G	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	V	P	H	G	K	S	A	C	V	K	Q	P	F	V	L	F	A	R	K	A	Q	A	I	D	W	K	A	S	D	G	E	D	V	N	C	W	I	C	L	G	V	P	Q	S	G	E	E	D	Q	V	K	I	I	G	T	L	C	R	K
Secondary structure
SS confidence
Disorder																											?	?	?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.
Sequence		I	I	H	K	E	F	I	H	Q	L	Q	Q	G	D	T	D	Q	V	L	A	L	L	N	Q	T	L	S	S
Secondary structure
SS confidence
Disorder																											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2a0j chain A Region: 3 - 143 Aligned: 140 Modelled: 141 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:pts system, nitrogen regulatory iia protein; PDBTitle: crystal structure of nitrogen regulatory protein iia-ntr from2 neisseria meningitidis Phyre2 PDB 3urr chain B Region: 3 - 145 Aligned: 140 Modelled: 143 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: B: PDB Molecule:pts iia-like nitrogen-regulatory protein ptsn; PDBTitle: structure of pts iia-like nitrogen-regulatory protein ptsn (bth_i0484)2 (ptsn) Phyre2 PDB 1a6j chain A Region: 1 - 145 Aligned: 144 Modelled: 145 Confidence: 100.0% Identity: 21% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: IIA domain of mannitol-specific and ntr phosphotransferase EII Phyre2 PDB 3oxp chain B Region: 3 - 145 Aligned: 139 Modelled: 143 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:phosphotransferase enzyme ii, a component; PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution Phyre2 PDB 3oxp chain A Region: 3 - 145 Aligned: 139 Modelled: 143 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:phosphotransferase enzyme ii, a component; PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution Phyre2 PDB 1a3a chain A Region: 1 - 143 Aligned: 138 Modelled: 143 Confidence: 100.0% Identity: 23% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: IIA domain of mannitol-specific and ntr phosphotransferase EII Phyre2 PDB 2oq3 chain A Region: 2 - 144 Aligned: 138 Modelled: 143 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:mannitol-specific cryptic phosphotransferase PDBTitle: solution structure of the mannitol- specific cryptic2 phosphotransferase enzyme iia cmtb from escherichia coli Phyre2 PDB 3bjv chain A Region: 2 - 148 Aligned: 142 Modelled: 145 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:rmpa; PDBTitle: the crystal structure of a putative pts iia(ptxa) from streptococcus2 mutans Phyre2 PDB 2oqt chain D Region: 3 - 148 Aligned: 141 Modelled: 144 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: D: PDB Molecule:hypothetical protein spy0176; PDBTitle: structural genomics, the crystal structure of a putative2 pts iia domain from streptococcus pyogenes m1 gas Phyre2 PDB 1xiz chain A Region: 3 - 147 Aligned: 143 Modelled: 145 Confidence: 100.0% Identity: 20% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: IIA domain of mannitol-specific and ntr phosphotransferase EII Phyre2 PDB 1hyn chain Q Region: 4 - 146 Aligned: 143 Modelled: 143 Confidence: 98.3% Identity: 20% PDB header:membrane protein Chain: Q: PDB Molecule:band 3 anion transport protein; PDBTitle: crystal structure of the cytoplasmic domain of human2 erythrocyte band-3 protein Phyre2 PDB 1hyn chain P Region: 4 - 146 Aligned: 143 Modelled: 143 Confidence: 98.3% Identity: 20% Fold: Phoshotransferase/anion transport protein Superfamily: Phoshotransferase/anion transport protein Family: Anion transport protein, cytoplasmic domain Phyre2 PDB 2v8k chain A Region: 81 - 129 Aligned: 44 Modelled: 49 Confidence: 25.2% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:pectate lyase; PDBTitle: structure of a family 2 pectate lyase in complex with2 trigalacturonic acid Phyre2 PDB 1gjj chain A domain 1 Region: 33 - 67 Aligned: 30 Modelled: 35 Confidence: 9.8% Identity: 23% Fold: LEM/SAP HeH motif Superfamily: LEM domain Family: LEM domain Phyre2 PDB 3dfg chain A Region: 19 - 47 Aligned: 28 Modelled: 29 Confidence: 6.1% Identity: 11% PDB header:recombination Chain: A: PDB Molecule:regulatory protein recx; PDBTitle: crystal structure of recx: a potent inhibitor protein of2 reca from xanthomonas campestris Phyre2 PDB 1pch chain A Region: 1 - 36 Aligned: 36 Modelled: 36 Confidence: 6.1% Identity: 22% Fold: HPr-like Superfamily: HPr-like Family: HPr-like Phyre2 PDB 2voi chain B Region: 17 - 33 Aligned: 17 Modelled: 17 Confidence: 6.0% Identity: 18% PDB header:apoptosis Chain: B: PDB Molecule:bh3-interacting domain death agonist p13; PDBTitle: structure of mouse a1 bound to the bid bh3-domain Phyre2 1 c2a0jA_ 2 c3urrB_ 3 d1a6ja_ 4 c3oxpB_ 5 c3oxpA_ 6 d1a3aa_ 7 c2oq3A_ 8 c3bjvA_ 9 c2oqtD_ 10 d1xiza_ 11 c1hynQ_ 12 d1hynp_ 13 c2v8kA_ 14 d1gjja1 15 c3dfgA_ 16 d1pcha_ 17 c2voiB_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2a0jA_ 100.0 27 PDB header:transferase Chain: A: PDB Molecule:pts system, nitrogen regulatory iia protein; PDBTitle: crystal structure of nitrogen regulatory protein iia-ntr from2 neisseria meningitidis 2 c3urrB_ 100.0 26 PDB header:transferase Chain: B: PDB Molecule:pts iia-like nitrogen-regulatory protein ptsn; PDBTitle: structure of pts iia-like nitrogen-regulatory protein ptsn (bth_i0484)2 (ptsn) 3 d1a6ja_ 100.0 21 Fold:Phoshotransferase/anion transport protein Superfamily:Phoshotransferase/anion transport protein Family:IIA domain of mannitol-specific and ntr phosphotransferase EII 4 c3oxpB_ 100.0 16 PDB header:transferase Chain: B: PDB Molecule:phosphotransferase enzyme ii, a component; PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution 5 c3oxpA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:phosphotransferase enzyme ii, a component; PDBTitle: structure of phosphotransferase enzyme ii, a component from yersinia2 pestis co92 at 1.2 a resolution 6 d1a3aa_ 100.0 23 Fold:Phoshotransferase/anion transport protein Superfamily:Phoshotransferase/anion transport protein Family:IIA domain of mannitol-specific and ntr phosphotransferase EII 7 c2oq3A_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:mannitol-specific cryptic phosphotransferase PDBTitle: solution structure of the mannitol- specific cryptic2 phosphotransferase enzyme iia cmtb from escherichia coli 8 c3bjvA_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:rmpa; PDBTitle: the crystal structure of a putative pts iia(ptxa) from streptococcus2 mutans 9 c2oqtD_ 100.0 13 PDB header:transferase Chain: D: PDB Molecule:hypothetical protein spy0176; PDBTitle: structural genomics, the crystal structure of a putative2 pts iia domain from streptococcus pyogenes m1 gas 10 d1xiza_ 100.0 20 Fold:Phoshotransferase/anion transport protein Superfamily:Phoshotransferase/anion transport protein Family:IIA domain of mannitol-specific and ntr phosphotransferase EII 11 c1hynQ_ 98.3 20 PDB header:membrane protein Chain: Q: PDB Molecule:band 3 anion transport protein; PDBTitle: crystal structure of the cytoplasmic domain of human2 erythrocyte band-3 protein 12 d1hynp_ 98.3 20 Fold:Phoshotransferase/anion transport protein Superfamily:Phoshotransferase/anion transport protein Family:Anion transport protein, cytoplasmic domain 13 c2v8kA_ 25.2 14 PDB header:lyase Chain: A: PDB Molecule:pectate lyase; PDBTitle: structure of a family 2 pectate lyase in complex with2 trigalacturonic acid 14 d1gjja1 9.8 23 Fold:LEM/SAP HeH motif Superfamily:LEM domain Family:LEM domain 15 c3dfgA_ 6.1 11 PDB header:recombination Chain: A: PDB Molecule:regulatory protein recx; PDBTitle: crystal structure of recx: a potent inhibitor protein of2 reca from xanthomonas campestris 16 d1pcha_ 6.1 22 Fold:HPr-like Superfamily:HPr-like Family:HPr-like 17 c2voiB_ 6.0 18 PDB header:apoptosis Chain: B: PDB Molecule:bh3-interacting domain death agonist p13; PDBTitle: structure of mouse a1 bound to the bid bh3-domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0