Email l.a.kelley@imperial.ac.uk Description P0C7Z3 Date Tue Jul 17 17:05:08 BST 2012 Unique Job ID e38ff2908a915b00

Summary

Top model

Image coloured by rainbow N → C terminus Close Jmol

Model (left) based on template c1dtcA_ Top template information PDB header:toxin Chain: A: PDB Molecule:acetyl-delta-toxin; PDBTitle: delta-toxin and analogues as peptide models for protein ion2 channels Confidence and coverage Confidence: 13.4% Coverage: 86% 18 residues ( 86% of your sequence) have been modelled with 13.4% confidence by the single highest scoring template. You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library. Please note: You must be registered and logged in to use Phyrealarm. 3D viewing Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1dtc chain A Region: 4 - 21 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 39% PDB header:toxin Chain: A: PDB Molecule:acetyl-delta-toxin; PDBTitle: delta-toxin and analogues as peptide models for protein ion2 channels Phyre2 PDB 2dtb chain A Region: 4 - 21 Aligned: 18 Modelled: 18 Confidence: 13.4% Identity: 39% PDB header:toxin Chain: A: PDB Molecule:delta-toxin; PDBTitle: delta-toxin and analogues as peptide models for protein ion2 channels Phyre2 PDB 2kam chain A Region: 4 - 21 Aligned: 18 Modelled: 18 Confidence: 13.1% Identity: 39% PDB header:toxin Chain: A: PDB Molecule:delta-hemolysin; PDBTitle: nmr structure of delta-toxin from staphylococcus aureus in2 cd3oh Phyre2 PDB 1fme chain A Region: 9 - 21 Aligned: 13 Modelled: 13 Confidence: 12.0% Identity: 46% PDB header:de novo protein Chain: A: PDB Molecule:fsd-ey peptide; PDBTitle: solution structure of fsd-ey, a novel peptide assuming a2 beta-beta-alpha fold Phyre2 PDB 1fsv chain A Region: 9 - 21 Aligned: 13 Modelled: 13 Confidence: 10.8% Identity: 46% PDB header:beta beta alpha motif Chain: A: PDB Molecule:full sequence design 1 of beta beta alpha motif; PDBTitle: full sequence design 1 (fsd-1) of beta beta alpha motif,2 nmr, minimized average structure Phyre2 PDB 1fsd chain A Region: 9 - 21 Aligned: 13 Modelled: 13 Confidence: 10.8% Identity: 46% PDB header:novel sequence Chain: A: PDB Molecule:full sequence design 1 of beta beta alpha motif; PDBTitle: full sequence design 1 (fsd-1) of beta beta alpha motif,2 nmr, 41 structures Phyre2 PDB 2dal chain A Region: 11 - 19 Aligned: 9 Modelled: 9 Confidence: 10.0% Identity: 67% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein kiaa0794; PDBTitle: solution structure of the novel identified uba-like domain2 in the n-terminal of human fas associated factor 1 protein Phyre2 PDB 1rp3 chain B Region: 9 - 19 Aligned: 11 Modelled: 11 Confidence: 5.2% Identity: 73% Fold: Non-globular all-alpha subunits of globular proteins Superfamily: Anti-sigma factor FlgM Family: Anti-sigma factor FlgM Phyre2 PDB 2zxe chain G Region: 2 - 21 Aligned: 20 Modelled: 20 Confidence: 5.1% Identity: 30% PDB header:hydrolase/transport protein Chain: G: PDB Molecule:phospholemman-like protein; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state Phyre2 1 c1dtcA_ 2 c2dtbA_ 3 c2kamA_ 4 c1fmeA_ 5 c1fsvA_ 6 c1fsdA_ 7 c2dalA_ 8 d1rp3b_ 9 c2zxeG_

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0