Secondary structure and disorder prediction

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Sequence

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Secondary structure

SS confidence

Disorder

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Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2jzf chain A Region: 2 - 7 Aligned: 6 Modelled: 6 Confidence: 10.6% Identity: 67% PDB header:viral protein Chain: A: PDB Molecule:replicase polyprotein 1ab; PDBTitle: nmr conformer closest to the mean coordinates of the domain 513-651 of2 the sars-cov nonstructural protein nsp3 Phyre2 PDB 2kqv chain A Region: 2 - 7 Aligned: 6 Modelled: 6 Confidence: 9.0% Identity: 67% PDB header:viral protein Chain: A: PDB Molecule:non-structural protein 3; PDBTitle: sars coronavirus-unique domain (sud): three-domain molecular2 architecture in solution and rna binding. i: structure of the sud-m3 domain of sud-mc Phyre2 1 c2jzfA_ 2 c2kqvA_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2jzfA_ 10.6 67 PDB header:viral protein Chain: A: PDB Molecule:replicase polyprotein 1ab; PDBTitle: nmr conformer closest to the mean coordinates of the domain 513-651 of2 the sars-cov nonstructural protein nsp3 2 c2kqvA_ 9.0 67 PDB header:viral protein Chain: A: PDB Molecule:non-structural protein 3; PDBTitle: sars coronavirus-unique domain (sud): three-domain molecular2 architecture in solution and rna binding. i: structure of the sud-m3 domain of sud-mc

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0