Phyre 2 Results for Q99ML1

Email	l.a.kelley@imperial.ac.uk
Description	Q99ML1
Date	Wed Jul 10 14:26:39 BST 2013
Unique Job ID	07762139a7395c41
Sequence	MARARQEGSS ... Download FASTA

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:30.010 Y:20.540 Z:37.871

Model (left) based on template c2m04B_

Top template information

PDB header:apoptosis/protein binding
Chain: B: PDB Molecule:bcl-2-binding component 3;
PDBTitle: solution structure of bcl-xl in complex with puma bh3 peptide

Confidence and coverage

Confidence:

1.2%

Coverage:

13%

25 residues ( 13% of your sequence) have been modelled with 1.2% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

Please note: You must be registered and logged in to use Phyrealarm.

Warning: 78% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M A R A R Q E G S S P E P V E G L A R D S P R P F P L G R L M P S A V S C S L C E P G L P A A P A A P A L L P A A Y L C

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence A P T A P P A V T A A L G G P R W P G G H R S R P R G P R P D G P Q P S L S P A Q Q H L E S P V P S A P E A L A G G P T

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence Q A A P G V R V E E E E W A R E I G A Q L R R M A D D L N A Q Y E R R R Q E E Q H R H R P S P W R V M Y N L F M G L L P

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 190 . . .

Sequence L P R D P G A P E M E P N

Secondary structure

SS confidence

Disorder ?
? ? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 78%)

Alpha helix ( 31%)

Beta strand ( 0%)

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

No hits with confidence > 5%