Email l.a.kelley@imperial.ac.uk Description P0C818 Date Tue Jul 17 17:05:09 BST 2012 Unique Job ID 427f0036a3737e09

Summary

Top model

Image coloured by rainbow N → C terminus Close Jmol

Model (left) based on template c1dtcA_ Top template information PDB header:toxin Chain: A: PDB Molecule:acetyl-delta-toxin; PDBTitle: delta-toxin and analogues as peptide models for protein ion2 channels Confidence and coverage Confidence: 7.3% Coverage: 90% 18 residues ( 90% of your sequence) have been modelled with 7.3% confidence by the single highest scoring template. You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library. Please note: You must be registered and logged in to use Phyrealarm. 3D viewing Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1dtc chain A Region: 3 - 20 Aligned: 18 Modelled: 18 Confidence: 7.3% Identity: 44% PDB header:toxin Chain: A: PDB Molecule:acetyl-delta-toxin; PDBTitle: delta-toxin and analogues as peptide models for protein ion2 channels Phyre2 PDB 2dtb chain A Region: 3 - 21 Aligned: 19 Modelled: 19 Confidence: 7.1% Identity: 42% PDB header:toxin Chain: A: PDB Molecule:delta-toxin; PDBTitle: delta-toxin and analogues as peptide models for protein ion2 channels Phyre2 1 c1dtcA_ 2 c2dtbA_

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0