Email l.a.kelley@imperial.ac.uk Description A6X977 Date Sun Jul 8 11:45:02 BST 2012 Unique Job ID 8d1e852689dc89f1

Summary

Top model

Image coloured by rainbow N → C terminus Close Jmol

Model (left) based on template d1m5za_ Top template information Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain Confidence and coverage Confidence: 10.7% Coverage: 25% 15 residues ( 25% of your sequence) have been modelled with 10.7% confidence by the single highest scoring template. You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library. Please note: You must be registered and logged in to use Phyrealarm. 3D viewing Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1m5z chain A Region: 11 - 25 Aligned: 15 Modelled: 15 Confidence: 10.7% Identity: 33% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: PDZ domain Phyre2 PDB 2fyu chain K domain 1 Region: 44 - 55 Aligned: 12 Modelled: 12 Confidence: 10.2% Identity: 17% Fold: Single transmembrane helix Superfamily: Subunit XI (6.4 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Family: Subunit XI (6.4 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Phyre2 PDB 1zu1 chain A domain 2 Region: 40 - 55 Aligned: 16 Modelled: 16 Confidence: 5.8% Identity: 38% Fold: beta-beta-alpha zinc fingers Superfamily: beta-beta-alpha zinc fingers Family: HkH motif-containing C2H2 finger Phyre2 1 d1m5za_ 2 d2fyuk1 3 d1zu1a2

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0