Phyre 2 Results for A2A5X4

Email	l.a.kelley@imperial.ac.uk
Description	A2A5X4
Date	Wed Jul 10 14:30:30 BST 2013
Unique Job ID	f7bfdc6316cc952e
Sequence	MADSCCPENP ... Download FASTA

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:31.348 Y:39.995 Z:45.301

Model (left) based on template c4bstD_

Top template information

PDB header:signaling protein
Chain: D: PDB Molecule:r-spondin-1;
PDBTitle: structure of the ectodomain of lgr5 in complex with r-spondin-12 (fu1fu2) in p6122 crystal form

Confidence and coverage

Confidence:

5.7%

Coverage:

13%

45 residues ( 13% of your sequence) have been modelled with 5.7% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

Please note: You must be registered and logged in to use Phyrealarm.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M A D S C C P E N P T A V P T V P T I S T C S N G G S I R N A I R L P S S C R C R T W Q L V T H Q E N R Q G P D S V P V

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ?
?
?
? ? ?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence S S E P V S C P S T C F P E T P C V G F I C Q P I G S H M A C C A S D T G G S P H P A A S C Q P S C L E S A G C H T M C

Secondary structure

SS confidence

Disorder
? ? ?
? ?
?
?
? ? ? ?
?
? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence Y E N S S C H Q S S G Q G S A C T S G S C Q T A C G P S A S C D D R S C Q P S C S E A T S Y A E T P C L P A G C E A G S

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ?
? ?
? ? ? ? ? ? ? ? ?
? ?
? ? ?
?
? ?
?
?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence C Q P T S C Q G G S H Q P T R G E G Q L C Q S V Y Y Q P I C Y V L K S C Q S T P C M S V S C Q P L T C M C F C S Q T C C

Secondary structure

SS confidence

Disorder ? ? ?
?
? ?
? ?
? ? ? ? ?
?
?
? ? ?
?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence V P P T C Q P L H C Q T T P I I S F I C Q P V A P C Q S P C F L K S S S K S A S C V M I S G Q Q I C G G P T P D Q S G C

Secondary structure

SS confidence

Disorder ? ?
? ?
?
?
? ? ? ? ?
?
? ?
? ? ? ?
?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . .

Sequence Q S P S C H P P C C V T G L G Q P S S S G P G C C P P T S P D I C Q A G T Y G P T S

Secondary structure

SS confidence

Disorder ? ?
? ? ? ?
? ?
? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 42%)

Alpha helix ( 1%)

Beta strand ( 3%)

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region