Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionC1P619
DateWed Jan 25 15:20:08 GMT 2012
Unique Job IDe1cb93505c05aaeb

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3pp4P_
Top template information
PDB header:immune system
Chain: P: PDB Molecule:b-lymphocyte antigen cd20;
PDBTitle: epitope characterization and crystal structure of ga101 provide2 insights into the molecular basis for the type i / type ii3 distinction of anti- cd20 antibodies
Confidence and coverage
Confidence: 10.8% Coverage: 44%
7 residues ( 44% of your sequence) have been modelled with 10.8% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
Warning: 69% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10......
Sequence  MNNSTKFCFSRFRTGN
Secondary structure 




SS confidence 















Disorder  ?????




??????
Disorder confidence 















 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3pp4 chain P

3D model

Region: 4 - 10
Aligned: 7
Modelled: 7
Confidence: 10.8%
Identity: 57%
PDB header:immune system
Chain: P: PDB Molecule:b-lymphocyte antigen cd20;
PDBTitle: epitope characterization and crystal structure of ga101 provide2 insights into the molecular basis for the type i / type ii3 distinction of anti- cd20 antibodies

Phyre2

PDB 2osl chain Q

3D model

Region: 4 - 10
Aligned: 7
Modelled: 7
Confidence: 9.6%
Identity: 57%
PDB header:immune system
Chain: Q: PDB Molecule:b-lymphocyte antigen cd20;
PDBTitle: crystal structure of rituximab fab in complex with an2 epitope peptide

Phyre2
1

c3pp4P_
2

c2oslQ_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3pp4P_



10.8 57 PDB header:immune system
Chain: P: PDB Molecule:b-lymphocyte antigen cd20;
PDBTitle: epitope characterization and crystal structure of ga101 provide2 insights into the molecular basis for the type i / type ii3 distinction of anti- cd20 antibodies
2c2oslQ_



9.6 57 PDB header:immune system
Chain: Q: PDB Molecule:b-lymphocyte antigen cd20;
PDBTitle: crystal structure of rituximab fab in complex with an2 epitope peptide

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0