ConFunc - Conserved residue Function Prediction Server

ConFunc Example Results

view the full results page for this example: http://www.sbg.bio.ic.ac.uk/confunc/qconfunc_report.cgi?jobid=example
or work through the explanation of the results page below.

The Top of The Results Page 

• As your job runs the results page will continue to be updated. At the top of the page the status is shown.
• The submission details are also printed for information as shown in the figure below.

Results Data Files 

• The first set of results contain the data files that ConFunc has generated during the prediction process. They consist of:
  • PSI-BLAST output
  • MUSLCE alignment of annotated sequences
  • MUSCLE alignment of annotated sequences (with gaps in the query sequence removed)
• The number of annotated homolouges identified is also displayed.

  As shown below, each of these can be clicked on to download the relevant file.

• If a job has not been successful then a message should be displayed informing you and the option to download files
  will not be displayed.

GO Predictions 

• Finally on the results page the predicted and rejected GO terms are displayed. The predicted terms are shown first.
• For each GO term the following are displayed:
  • a description of its function
  • its level (with Molecular function considered to be level 0)
  • a GO term c-value generated by ConFunc
  • the count - absolute number of time GO term present in set of homologues
  • frequency - percentage presence of GO term in set of annotated homologues

Some of the results for the example are shown below:

GO term sub-alignments 

A sub-alignment is associated with each GO term. Simply click on a term is display its sub-alignment. So you would click on GO:0003924 in the above example to view its sub-alignment.

A portion of this sub-alignment is shown below.

• Functional residues identified by ConFunc are coloured.
• The key at the top describes the colouring scheme. The darker the colour the more conserved it is.
  

view the full results page for this example: http://www.sbg.bio.ic.ac.uk/confunc/qconfunc_report.cgi?jobid=example