Division of Molecular Biosciences
Department of Life Sciences
Faculty of Natural Sciences

Welcome to the Structural Bioinformatics Group at Imperial College London. The group is led by Professor Michael J.E. Sternberg (also Director of the Centre for Bioinformatics).

  • Modelling protein folding

    slideshow/photos/file01.jpg

    image001
  • Normal mode analysis

    slideshow/photos/file02.jpg

    image002
  • Modelling protein folding

    slideshow/photos/file03.jpg

    image003
  • Receptor modelling

    slideshow/photos/file04.jpg

    image004
  • Protein docking and receptor modelling

    slideshow/photos/file05.jpg

    image005
  • Modelling protein folding

    slideshow/photos/file06.jpg

    image006
  • Protein-Ligand interactions

    slideshow/photos/file07.jpg

    image007
  • Molecular modelling

    slideshow/photos/file08.jpg

    image008

 

The main research interests of the group are:

  • The development of computer algorithms:
    - to predict protein structure from sequence
    - to suggest protein function from sequence or structure
    - to predict the structure of a protein complex starting from the unbound components
  • The analysis of protein structure and function with the aim of deriving evolutionary insights
  • The modelling and comparison of biology networks to provide insights into Systems Biology
  • The modelling of the activity and toxicity of small molecules as an aid to the design of novel drugs.

For full details of research please see the Research page. Much of our research is disseminated in the form of publicly available software, databases and web based servers which can be found on the Tools page.

Related links (at Imperial College London)

- Centre for Bioinformatics (Director: Professor Michael Sternberg)
- Computational Bioinformatics Laboratory (Professor Stephen H. Muggleton)
- Theoretical Systems Biology Group (Professor Michael Stumpf)
- Centre for Integrative Systems Biology
- Institute of Systems and Synthetic Biology

SEARCH


PHYRE2
CombFunc
SuSPect
3DLigandSite
PINALOG
WINARNS
3D-PSSM
3D-GARDEN
WIBL