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Job DescriptionALS_intensive
Confidence100.00%DateTue Feb 21 10:39:47 GMT 2012
Rank7Aligned Residues522
% Identity20%Templatec2z81A_
PDB info PDB header:immune systemChain: A: PDB Molecule:toll-like receptor 2, variable lymphocyte receptor b; PDBTitle: crystal structure of the tlr1-tlr2 heterodimer induced by binding of a2 tri-acylated lipopeptide
Resolution1.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   45....50.........60.........70.........80.........90.........100.........110.........120....
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Query Sequence  CVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENL
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Template Conservation    
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Template Sequence  LSCDASG. . . . . VCDGRSRSFTSIPSGLTAAMKSLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAFYSLGSL
Template Known Secondary structure 

TTS.....
TTS

SS

S


TT



SS



SSTTSS
TT


TTS



TTTTTT
TT
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   28.30.... .....40.........50.........60.........70.........80.........90.........100..
 
   125....130.........140.........150.........160..... ....170......... 180.........190.........200..
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Query Sequence  CHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGL. FEGLGSLWDLNLGW. NSLAVLPDAAFRGLGSLRELVLA
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Template Conservation    
 

 
 
  
       
  
  
 

 
             
  
  
 
                   
  
   
Template Sequence  EHLDLSDNHLSSLSSSWFGPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDFAGLTSLNELEIK
Template Known Secondary structure 

TTS


S

TT
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TT


SSS
SS
S
TT
TT

SSS


TTTTTT

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   103......110.........120.........130.........140.........150.........160.........170.........180..
 
   203......210.........220.........230.........240.........250.........260.........270....
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Query Sequence  GNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLS. . . . . . . .
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Template Conservation                                                     
                            
Template Sequence  ALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLELRDTNLARFQFSPLPVDEVSSPMKKLAFRGSVLT
Template Known Secondary structure  TT


TTTTTT
S
SBSTTSTTTBSS
B
TT





SS







S
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   183......190.........200.........210.........220.........230.........240.........250.........260..
 
   275....280.........290.........300.........310.........320.........330.........340....
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Query Sequence  . . . . . . . . . . HNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLT
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Template Conservation                                                                             
  
 
Template Sequence  DESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVTIRRLHIPQFYLFYDLSTVYSLLEKVKRIT
Template Known Secondary structure  GGGGG
TT

S


S




TTT




TT

S
B
S
GGGS



STT

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   263......270.........280.........290.........300.........310.........320.........330.........340..
 
   345....350.........360.........370.........380.........390.........400.........410.........420....
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Query Sequence  LDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVG
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Template Conservation                     
  
                       
  
                      
       
Template Sequence  VENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISR
Template Known Secondary structure  SS






TT



SS


T
TTSSTT


TTS



GGG
TT


TT
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   343......350.........360.........370.........380.........390.........400.........410.........420..
 
   425....430.........440.........450.........460.........470.........480.........490.........500...
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Query Sequence  . IEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLA
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Template Sequence  NTFHPMPDSCQWPEKMRFLNLSSTGIRVVKTCIPQTLEVLDVSNNNLDSFSL. . . . FLPRLQELYISRNKLKTLPDASL.
Template Known Secondary structure 






S




TT


TTS

S


TTS
TT
S

SS

S



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TT



SS

SS


GGG.
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   423......430.........440.........450.........460.........470.... .....480.........490.......
 
   504.....510.........520.... .....530.........540... ......550.........560.........570........
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Query Sequence  PLGRLRYLSLRNNSLRTFTPQ. . . . PPGLERLWLEGNPWDCGCP. LKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTY
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Template Conservation  .
  
  
 

 
 
  
       
  
  
 
  

  


         
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Template Sequence  . FPVLLVMKISRNQLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNKNSQKEQGSAK. . . . . . . . . . . . . . .
Template Known Secondary structure  .
TT



SS





TTGGGG
TT



SS
B



TTTS

B...............
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   498.500.........510.........520.........530.........540.........550.........560.
 
   579580.........590.........600....
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Query Sequence  NNITCASPPEVVGLDLRDLSEAHFAP
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Template Conservation  ....
  
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Template Sequence  . . . . CSGS. . . . GKPVRSII. . . . CP
Template Known Secondary structure  ....BTTT....

BGGG

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   562... ....570... ..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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