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Job DescriptionALS_intensive
Confidence100.00%DateTue Feb 21 10:39:47 GMT 2012
Rank28Aligned Residues334
% Identity27%Templatec3o6nA_
PDB info PDB header:protein bindingChain: A: PDB Molecule:apl1; PDBTitle: crystal structure of apl1 leucine-rich repeat domain
Resolution1.85 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   74.....80.........90.........100.........110.........120.........130.........140.........150...
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Query Sequence  GGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGL
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Template Conservation   

  
 

 
 
  

   
  
  
  



 
 
  
    
  
  
  
 
  
 
                   
Template Sequence  NNQKIVTFKNSTMRKLPAALLDSFRQVELLNLNDLQIEEIDTYAFAYAHTIQKLYMGFNAIRYLPPHVFQNVPLLTVLVL
Template Known Secondary structure 


SS
S
T



S
TTS



TTTTTT
TT



SS





TTTTTT
TT


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   178.180.........190.........200.........210.........220.........230.........240.........250.......
 
   154.....160.........170.........180.........190.........200.........210.........220.........230...
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Query Sequence  SNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAI
Query Conservation 
 
 
             
  
                                                          
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Template Conservation                                                                   ...............
Template Sequence  ERNDLSSLPRGIFHNTPKLTTLSMSNNNLERIEDDTFQATTSLQNLQLSSNRLTHVDLSLIPSLF. . . . . . . . . . . . . . .
Template Known Secondary structure 
SS





TTTTTT
TT



SS


B

TTTTSS
TT



SS

SB

GGG
TT
S...............
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   258.260.........270.........280.........290.........300.........310.........320..
 
   234.....240.........250.........260.........270.........280.........290.........300.........310...
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Query Sequence  KANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDL
Query Conservation                                                                                  
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   314.....320.........330.........340.........350.........360.........370.........380.........390...
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Query Sequence  HFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHL
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Template Conservation  ..............................................................                  
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HANVSYNLLSTLAIPIAV
Template Known Secondary structure  ..............................................................

SS

S

SS
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   323......330.........340
 
   394.....400.........410.........420.........430.........440.........450.........460.........470...
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Query Sequence  EGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAEL
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Template Conservation                                                                              
   
Template Sequence  EELDASHNSINVVRGPVNVELTILKLQHNNLTDTAWLLNYPGLVEVDLSYNELEKIMYHPFVKMQRLERLYISNNRLVAL
Template Known Secondary structure  S

SS






SS



SS




GGGGG
TT
S

SS


SGGGTT
SS



SS


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   341........350.........360.........370.........380.........390.........400.........410.........420
 
   474.....480.........490.........500.........510.........520.... .....530.........540.........550..
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Query Sequence  PADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQ. PPGLERLWLEGNPWDCGCPLKALRDFAL
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Template Conservation    .       
  
 
  
    
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Template Sequence  NL. YGQPIPTLKVLDLSHNHLLHVERN. QPQFDRLENLYLDHNSIVTLKLSTHHTLKNLTLSHNDWDCNSLRALFRNVAR
Template Known Secondary structure 
.SSS

TT



SS




GGG.TT
S

SS







TT


S

SS
TTT

T
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   421. .......430.........440...... ...450.........460.........470.........480.........490........
 
   553 ......560......
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Query Sequence  Q. . . . . . . NPSAVPRFVQAIC
Query Conservation   ....... 
      
  
 
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Template Conservation           
        

 
Template Sequence  PAVDDADQHCKIDYQLEHGLC
Template Known Secondary structure  TTB



S


TT
TT
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   499500.........510.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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