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Job DescriptionALS_intensive
Confidence100.00%DateTue Feb 21 10:39:47 GMT 2012
Rank4Aligned Residues527
% Identity24%Templatec3j0aB_
PDB info PDB header:immune systemChain: B: PDB Molecule:toll-like receptor 5; PDBTitle: homology model of human toll-like receptor 5 fitted into an electron2 microscopy single particle reconstruction
Resolution26.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   45....50.........60.........70.........80.........90.........100.........110. ........120...
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Query Sequence  CVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLG. SLEPQALLGLEN
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Template Conservation 
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Template Sequence  CSFDGRI. . . . . . AFYRFCNLTQVPQVLN. TTERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPN
Template Known Secondary structure 
SSSS......S


SS

TTS
T.T

S




SSS
SS

S
S
TT




SSTTSS
TT
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   24.....30 .........40...... ...50.........60.........70.........80.........90......
 
   124.....130.........140.........150.........160.. .......170.........180.........190.........200.
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Query Sequence  LCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLE. . DGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVL
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Template Conservation 
  
 

 
 
  
       
  
  
 

 
 
            
  
  
 

 
 
              
  
 
Template Sequence  LRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSID
Template Known Secondary structure 


TT



B

TTSS
S
SS



TT


SS

STT


SS
SS

S








GGGGT
SS

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   97..100.........110.........120.........130.........140.........150.........160.........170......
 
   202.......210.........220.........230.........240...
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Query Sequence  AGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation                                            ......................................
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Template Conservation 
                    
       
                                                  
Template Sequence  FSSNQIFLVCEHELEPLQGKTLSFFSLAANSLYSRVSVDWGKCMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAF
Template Known Secondary structure  SS





SGGG
SS




SBS








SSS
TTTT

BSB
SS

SSTTGGGTS
S

BS
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   177..180.........190.........200.........210.........220.........230.........240.........250......
 
   244.....250.........260.........270.........280.........290
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLL
Query Conservation  .................................                                               
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Template Conservation                                                                                
 
Template Sequence  SLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLD
Template Known Secondary structure 

S


B
SSS
SSSTTTTTTTTTS



TT



BB
S

SSS






S




B
TTTTTT
S
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   257..260.........270.........280.........290.........300.........310.........320.........330......
 
   291........300.........310.........320.........330.........340.........350.........360.........370
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Query Sequence  GLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLS
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Template Conservation   
                       
                                                      
Template Sequence  NLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLV
Template Known Secondary structure  S



S


S


S
S
SS
TT



S






SSSS
S




T

S


SS



SS



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   337..340.........350.........360.........370.........380.........390.........400.........410......
 
   371........380.........390.........400.........410.........420.........430.........440.........450
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Query Sequence  GNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLP
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Template Conservation                                                                    ..            
Template Sequence  TLPKINLTANLIHLSENRLENLDILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGE. . NMLQLAWETELC
Template Known Secondary structure 





TT



S



SSTT
TT


SS






SSSSS
S
TT



S..


SSS

S


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   417..420.........430.........440.........450.........460.........470.........480.. .......490....
 
   451........460.........470.........480.........490.........500.........510.........520.... .....
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Query Sequence  HRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQ. PPGLE
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Template Conservation           
  
 
  
 
          
  
  
 

 
 
  
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Template Sequence  WDVFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHNDL. . PANLEILDISRNQLLAPNPDVFVSLS
Template Known Secondary structure  SS
SS
B






TT

TTSTTT

S

S


SS





..
S








S


SS

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   495....500.........510.........520.........530.........540...... ...550.........560.........570..
 
   530.........540.........550.........560.........570.........580.........590........
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Query Sequence  RLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYNNITCASPPEVVGLDLRDLS
Query Conservation   
 
  
   
 
 
  
  
 
  
      
  
  
  
  
 
  
      
  
  
 
 

 
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Template Conservation   
 

 

  
 
    
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Template Sequence  VLDITHNKFICECELSTFINWLNHTNVTIAGPPA. . . . . . . . . . . . . . . . DIYCVYPDSFSGVSLFSLS
Template Known Secondary structure 



SSS

TTGGG


GG................G



S
SSS
S

TTT

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   573......580.........590.........600...... ...610.........620.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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