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Job DescriptionALS_intensive
Confidence100.00%DateTue Feb 21 10:39:47 GMT 2012
Rank5Aligned Residues523
% Identity20%Templatec2z63A_
PDB info PDB header:immune systemChain: A: PDB Molecule:toll-like receptor 4, variable lymphocyte receptor b; PDBTitle: crystal structure of the tv8 hybrid of human tlr4 and hagfish vlrb.61
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   43......50.........60.........70.........80.........90.........100.........110.........120..
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Query Sequence  AACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLE
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Template Conservation    
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Template Sequence  EPCVEVVPNIT. . . . YQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLS
Template Known Secondary structure 

STTT....

SS

SS

SSS
SS



S




TTTTTT
SS


TT




TTTTTT
T
Template Predicted Secondary structure 






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   27..30....... ..40.........50.........60.........70.........80.........90.........100..
 
   123......130.........140.........150.........160.........170.........180.........190.........200..
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Query Sequence  NLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLA
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Template Conservation   
  
 

 
 
  
    
  
  
  
 

 
 
  
          
  
 
                   
     
Template Sequence  HLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDL
Template Known Secondary structure  T


TT




TTTTTT
TT


TTS



STT
S
TT
TT



SS







GGGGG
TT


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   103......110.........120.........130.........140.........150.........160.........170.........180..
 
   203......210.........220.........230.........240.........250.........260.........270.........280..
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Query Sequence  GNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLL
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Template Conservation                                                                                  
Template Sequence  SSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGE
Template Known Secondary structure  TTS



GGGGT
TT



TT




TTTTTT
S

S
TTTTTT
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   183......190.........200.........210.........220.........230.........240.........250.........260..
 
   283......290.........300. ........310.........320.........
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Query Sequence  EDTFPGLLGLRVLRLSHNA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IASLRPRTFKDLHFLEELQLGHNRIRQL
Query Conservation                     .................................                            
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Template Conservation                                                                                  
Template Sequence  FRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKF
Template Known Secondary structure 



SS


TTTTGGGGGSTTS
STTTTGGGTT
SS

S

B

S



SS
B
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   263......270.........280.........290.........300.........310.........320.........330.........340..
 
   330.........340.........350.........360.........370.........380.........390.........400.........
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Query Sequence  AERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGL
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Template Conservation                                                                                  
Template Sequence  GQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLE
Template Known Secondary structure  SS

B
B
SS

S
BS

B



B
TT



SS

BT
S




S
ST
T
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   343......350.........360.........370.........380.........390.........400.........410.........420..
 
   410.........420.........430.........440.........450.........460.........470.. .......480........
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Query Sequence  SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAE. LPADALGPLQRAFWLD
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Template Conservation                            
                       
  
 
                
  
  
 
Template Sequence  QLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLD
Template Known Secondary structure  T


TTSS
TTS
TTTT
TT


TTS



TTTTTT
TT


TT
GGG
S

TT
TT

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   423......430.........440.........450.........460.........470.........480.........490.........500..
 
   489490.........500.........510.........520.... .....530.........540... ......550.........560...
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Query Sequence  VSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQ. . . . PPGLERLWLEGNPWDCGCP. LKALRDFALQNPSAVPRFVQ
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Template Conservation 

 
 
  
    
  
  
  
 

 
 
  
       
  
  
 
  

  
 
  
  
   
            
Template Sequence  LSQCQLEQLSPTAFNSLSSLQVLNMASNQLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNKNSQKEQGSAK
Template Known Secondary structure 
TTS



TTTTTT
TT



SS

S


TTTTTT
TT



SS
B


TTTTTGGGS

B
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   503......510.........520.........530.........540.........550.........560.........570.........580..
 
   564.....570.........580........
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Query Sequence  AICEGDDCQPPAYTYNNITCASPPE
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Template Conservation  ...................
     
Template Sequence  . . . . . . . . . . . . . . . . . . . CSGSGK
Template Known Secondary structure  ...................BTTT

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   583.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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