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Job DescriptionALS______
Confidence100.00%DateThu Feb 9 13:17:35 GMT 2012
Rank12Aligned Residues511
% Identity18%Templatec2z7xB_
PDB info PDB header:immune systemChain: B: PDB Molecule:toll-like receptor 1, variable lymphocyte receptor b; PDBTitle: crystal structure of the tlr1-tlr2 heterodimer induced by binding of a2 tri-acylated lipopeptide
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   54.....60.........70.........80.........90.........100.........110.........120.........130...
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Query Sequence  DELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQ
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Template Conservation      



 
 
  

  
   
  
 

 
 
  
       
  
  
 

 
 
  
    
  
  
  
 

 
 
Template Sequence  SEFLVDRSKNGLIHVPKDLSQKTTILNISQNYISELWTSDILSLSKLRILIISHNRIQYLDISVFKFNQELEYLDLSHNK
Template Known Secondary structure 



TTS

SS


S

TT
S

SS





TT
TT



SS


GGGGTT
TT



SS
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   25....30.........40.........50.........60.........70.........80.........90.........100....
 
   134.....140.........150.........160..... ....170.........180.........190.........200.........210..
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Query Sequence  LRSLALGTFAHTPALASLGLSNNRLSRLEDGL. FEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPA
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Template Sequence  LVKIS. . . CHPTVNLKHLDLSFNAFDALPICKEFGNMSQLKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKEDP
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S

SS

SS



GGGGG
TT

SS

GGGGGGGTTS

TTTTSS

T
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   105.... 110.........120.........130.........140.........150.........160.........170.........180.
 
   213......220.........230.........240.........250.........260.........270.........280.........290..
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Query Sequence  LFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGL
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Template Sequence  EGLQDFNTESLHIVFPTNKEFHFILDVSVKTVANLELSNIKCV. . . . . . . LEDNKCSYFLSILAKLQTNPKLSNLTLNNI
Template Known Secondary structure  TTTTT



SSS









TT
S


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STTTTGGGG
TT

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   182.......190.........200.........210.........220.... .....230.........240.........250....
 
   293......300.........310.........320.........330.........340.........350.........360.........370..
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Query Sequence  RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGN
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Template Conservation                                                 
                            
   
Template Sequence  ETTWNSFIRILQLVWHTTVWYFSISNVKLQGQLDFRDFDYSGTSLKALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVS
Template Known Secondary structure  TSS
SS









S







S
TT


S
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   255....260.........270.........280.........290.........300.........310.........320.........330....
 
   373......380.........390.........400.........410.........420..... ....430.........440.........
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Query Sequence  CLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGI. . . EEQSLWGLAELLELDLTSNQLTHL
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Template Sequence  GTRMVHMLCPSKISPFLHLDFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSLQQLDISQNSVSYDE
Template Known Secondary structure  SS







SS






SS


TTTTTT



SS



SS


BTT
TT



SS

B

G
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   335....340.........350.........360.........370.........380.........390.........400.........410....
 
   450.........460.........470.........480.........490.........500.........510.........520.... .
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Query Sequence  PHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQ. . . . P
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Template Sequence  KKGDCSWTKSLLSLNMSSNILTDTIFRCL. . PPRIKVLDLHSNKIKSIPKQ. VVKLEALQELNVASNQLKSVPDGIFDRL
Template Known Secondary structure  GG
S



TT



SS


GGGGGS
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TT



SS





GG.GGG
TT



SS





TTTTTT
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   415....420.........430.........440... ......450.........460... ......470.........480.........490.
 
   526...530.........540... ......550.........560.........570.........580.........590.........600....
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Query Sequence  PGLERLWLEGNPWDCGCP. LKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYNNITCASPPEVVGLDLRDLSEAHFAP
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Template Sequence  TSLQKIWLHTNPWDCSCPRIDYLSRWLNKNSQKEQGSAK. . . . . . . . . . . . . . . . . . . CSGS. . . . GKPVRSI. . . . ICP
Template Known Secondary structure  TT



SS
B


TTTTS

B...................BTTT....

BGGG
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   492.......500.........510.........520.........530 .... .....540. ...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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