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Job DescriptionALS______
Confidence100.00%DateThu Feb 9 13:17:35 GMT 2012
Rank9Aligned Residues363
% Identity32%Templatec2id5D_
PDB info PDB header:ligand binding protein,membrane proteinChain: D: PDB Molecule:leucine rich repeat neuronal 6a; PDBTitle: crystal structure of the lingo-1 ectodomain
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   41........50.........60.........70.........80.........90.........100.........110.........120
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Query Sequence  CPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLG
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Template Sequence  CPPRCECSAQDRA. . . . VLCHRKRFVAVPEGIP. . . RLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNN
Template Known Secondary structure 

SSSTTTT....

SS

SS

SS

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S




TTTTTT



S

TT




SS
STT
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   3......10..... ....20.........30. ........40.........50.........60.........70.....
 
   121........130.........140.........150.........160.........170.........180.........190.........200
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Query Sequence  LENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELV
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Template Conservation 
  
  
 

 
 
  
       
  
  
 
                                          
    
Template Sequence  LFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLT
Template Known Secondary structure 
TT


TTS

S


TTTTTT
TT



SS



TTTTTT
TT



TT


TTTTTT
TT

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   7980.........90.........100.........110.........120.........130.........140.........150........
 
   201........210.........220.........230.........240.........250.........260.........270.........280
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Query Sequence  LAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG
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Template Sequence  LEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTA
Template Known Secondary structure  S


SS

TT
TT

S




TT
S
S
TT



TT


TTTTTT


SSS

SS
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   159160.........170.........180.........190.........200.........210.........220.........230........
 
   281........290.........300.........310.........320.........330.........340.........350.........360
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Query Sequence  LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLG
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Template Conservation             
  
 
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Template Sequence  VPYLAVRHLVYLRFLNLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 

TTTTTT
TT



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   239240.........250......
 
   361........370.........380.........390.........400.........410.........420.........430.........440
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Query Sequence  LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELD
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   441........450.........460.........470.........480.........490.........500.........510.........520
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Query Sequence  LTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRT
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Template Conservation  ..........................              
  
  
 
  
 
  
    
  
  
  
 

 
 
  
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . YNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTT
Template Known Secondary structure  ..........................SS



TTSSTT
TT



SS

S
TTTTTT
TT


TTS

S
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   257..260.........270.........280.........290.........300.........310
 
   521.. ......530.........540.........550.........560.........570.........580.........590......
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Query Sequence  FTP. . . . QPPGLERLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYNNITCASPPEVVGLDLRD
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Template Conservation 
       
  
  
 
  

  


 
  
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Template Sequence  LEESVFHSVGNLETLILDSNPLACDCRLLWVFRRRWRLNFNRQ. . . . . . . . . . . . . . . . . . . . QPTCATPEFVQGKEFKD
Template Known Secondary structure 

GGG
S
GGG



SS

SGGGTTTTTTT
TT
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BSGGGTT
BGGG
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   311........320.........330.........340.........350... ......360.........370
 
   597.
Predicted Secondary structure 

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Query Sequence  LS
Query Conservation 
 
Alig confidence 

Template Conservation    
Template Sequence  FP
Template Known Secondary structure  S
Template Predicted Secondary structure 

Template SS confidence 

   371.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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