BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (262 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P58054 UPF0012 hydrolase ybeM n=121 Tax=Proteobacteria ...   531   e-150
UniRef50_UPI00019771AF Nitrilase/cyanide hydratase and apolipopr...   217   4e-55
UniRef50_A7A823 Putative uncharacterized protein n=2 Tax=Bifidob...   214   3e-54
UniRef50_A9WV78 Hydrolase, carbon-nitrogen family n=3 Tax=Microc...   172   9e-42
UniRef50_Q0S3S2 Possible amidohydrolase, carbon-nitrogen hydrola...   171   2e-41
UniRef50_UPI000197C0D6 hypothetical protein PretD1_21713 n=1 Tax...   169   1e-40
UniRef50_A9A651 Nitrilase/cyanide hydratase and apolipoprotein N...   165   2e-39
UniRef50_C0Z4R2 Putative uncharacterized protein n=1 Tax=Breviba...   164   2e-39
UniRef50_C4DVK2 Predicted amidohydrolase n=1 Tax=Stackebrandtia ...   160   3e-38
UniRef50_D1BX77 Nitrilase/cyanide hydratase and apolipoprotein N...   157   3e-37
UniRef50_D1A7Y1 Nitrilase/cyanide hydratase and apolipoprotein N...   151   2e-35
UniRef50_A1SD43 Nitrilase/cyanide hydratase and apolipoprotein N...   150   3e-35
UniRef50_A4ALG5 Putative hydrolase n=1 Tax=marine actinobacteriu...   150   4e-35
UniRef50_C1SI84 Predicted amidohydrolase n=1 Tax=Denitrovibrio a...   149   7e-35
UniRef50_UPI000186DBB5 conserved hypothetical protein n=1 Tax=Pe...   143   7e-33
UniRef50_UPI0001B416B7 carbon-nitrogen hydrolase n=1 Tax=Ferropl...   141   2e-32
UniRef50_A2BNC1 Predicted amidohydrolase n=1 Tax=Hyperthermus bu...   138   1e-31
UniRef50_Q7TQ94 Nitrilase homolog 1 n=6 Tax=Coelomata RepID=NIT1...   137   3e-31
UniRef50_D1T004 Nitrilase/cyanide hydratase and apolipoprotein N...   137   3e-31
UniRef50_C7QZX4 Nitrilase/cyanide hydratase and apolipoprotein N...   136   6e-31
UniRef50_Q86X76 Nitrilase homolog 1 n=34 Tax=Eumetazoa RepID=NIT...   134   2e-30
UniRef50_UPI0001924654 PREDICTED: similar to Nit protein 1 n=1 T...   134   3e-30
UniRef50_UPI0000382451 COG0388: Predicted amidohydrolase n=1 Tax...   134   4e-30
UniRef50_Q702A9 Putative predicted amidohydrolase n=6 Tax=Archae...   133   5e-30
UniRef50_D2R0U8 Nitrilase/cyanide hydratase and apolipoprotein N...   133   6e-30
UniRef50_B2J6W4 Nitrilase/cyanide hydratase and apolipoprotein N...   133   6e-30
UniRef50_A1RZK0 Nitrilase/cyanide hydratase and apolipoprotein N...   133   6e-30
UniRef50_A0JSW0 Nitrilase/cyanide hydratase and apolipoprotein N...   132   1e-29
UniRef50_P55175 UPF0012 hydrolase sll0601 n=46 Tax=Cyanobacteria...   131   2e-29
UniRef50_Q9HIW8 Nitrilase related protein n=2 Tax=Thermoplasma R...   131   2e-29
UniRef50_A2Q9D7 Catalytic activity: nitrilases catalyze a nitril...   130   5e-29
UniRef50_Q6L0F7 Carbon-nitrogen hydrolase family n=1 Tax=Picroph...   129   7e-29
UniRef50_D2A1E5 Putative uncharacterized protein GLEAN_07103 n=3...   129   7e-29
UniRef50_A0PVY5 Amidohydrolase n=12 Tax=Actinomycetales RepID=A0...   129   9e-29
UniRef50_Q6C005 YALI0F29139p n=1 Tax=Yarrowia lipolytica RepID=Q...   129   1e-28
UniRef50_B9ZGS1 Nitrilase/cyanide hydratase and apolipoprotein N...   126   7e-28
UniRef50_D1Y828 Hydrolase n=1 Tax=Pyramidobacter piscolens W5455...   125   1e-27
UniRef50_Q5A428 Nitrilase superfamily protein n=4 Tax=Candida Re...   125   1e-27
UniRef50_B0MEV6 Putative uncharacterized protein n=2 Tax=Clostri...   124   2e-27
UniRef50_UPI000051A529 PREDICTED: similar to Nitrilase and fragi...   124   2e-27
UniRef50_D1Y612 Hydrolase n=2 Tax=Bacteria RepID=D1Y612_9BACT         124   4e-27
UniRef50_O76463 Nitrilase homolog n=6 Tax=Bilateria RepID=NFT1_C...   122   1e-26
UniRef50_B9L3Z7 Hydrolase, carbon-nitrogen family protein n=8 Ta...   122   2e-26
UniRef50_A2BKF1 Predicted amidohydrolase n=1 Tax=Hyperthermus bu...   122   2e-26
UniRef50_UPI000185C288 hydrolase n=1 Tax=Corynebacterium amycola...   121   2e-26
UniRef50_P47016 Probable hydrolase NIT2 n=9 Tax=Saccharomycetace...   121   2e-26
UniRef50_C7NXL9 Nitrilase/cyanide hydratase and apolipoprotein N...   121   2e-26
UniRef50_C6CYG4 Nitrilase/cyanide hydratase and apolipoprotein N...   120   3e-26
UniRef50_C9D316 Hydrolase n=1 Tax=Silicibacter sp. TrichCH4B Rep...   120   6e-26
UniRef50_Q11M91 Nitrilase/cyanide hydratase and apolipoprotein N...   119   7e-26
UniRef50_C1TRG7 Predicted amidohydrolase n=1 Tax=Dethiosulfovibr...   119   7e-26
UniRef50_A6VWN8 Nitrilase/cyanide hydratase and apolipoprotein N...   119   8e-26
UniRef50_B6HUF1 Pc22g05380 protein n=28 Tax=Leotiomyceta RepID=B...   119   1e-25
UniRef50_O94660 Probable hydrolase nit2 n=2 Tax=Schizosaccharomy...   119   1e-25
UniRef50_B0SIF2 Amidohydrolase n=3 Tax=Bacteria RepID=B0SIF2_LEPBA    119   1e-25
UniRef50_Q23ND3 Hydrolase, carbon-nitrogen family protein n=1 Ta...   118   2e-25
UniRef50_B8D4L6 Nitrilase/cyanide hydratase and apolipoprotein N...   117   5e-25
UniRef50_Q9Y9L1 Putative hydrolase n=1 Tax=Aeropyrum pernix RepI...   116   6e-25
UniRef50_D0L1I4 Nitrilase/cyanide hydratase and apolipoprotein N...   116   9e-25
UniRef50_A5V962 Nitrilase/cyanide hydratase and apolipoprotein N...   116   9e-25
UniRef50_Q1PXD4 Similar to N-carbamoyl-D-amino acid hydrolase n=...   115   1e-24
UniRef50_C1B562 Putative hydrolase n=2 Tax=Actinomycetales RepID...   115   1e-24
UniRef50_B3E274 Nitrilase/cyanide hydratase and apolipoprotein N...   115   2e-24
UniRef50_A5GT50 Possible nitrilase n=5 Tax=Bacteria RepID=A5GT50...   114   3e-24
UniRef50_A7IJX5 Nitrilase/cyanide hydratase and apolipoprotein N...   114   3e-24
UniRef50_C5DKM8 KLTH0F05984p n=2 Tax=Saccharomycetaceae RepID=C5...   114   4e-24
UniRef50_Q557J5 Nitrilase homolog 1 n=1 Tax=Dictyostelium discoi...   114   4e-24
UniRef50_Q11146 UPF0012 hydrolase Rv0480c/MT0498 n=34 Tax=Actino...   114   5e-24
UniRef50_D2RIK2 Nitrilase/cyanide hydratase and apolipoprotein N...   113   6e-24
UniRef50_Q2QQ94 Os12g0502500 protein n=5 Tax=Spermatophyta RepID...   113   6e-24
UniRef50_C7N2Y0 Predicted amidohydrolase n=1 Tax=Slackia heliotr...   111   3e-23
UniRef50_C8RSM4 Carbon-nitrogen hydrolase n=3 Tax=Corynebacteriu...   110   4e-23
UniRef50_Q2NHR0 Predicted amidohydrolase n=1 Tax=Methanosphaera ...   110   5e-23
UniRef50_Q0HEI5 Nitrilase/cyanide hydratase and apolipoprotein N...   110   5e-23
UniRef50_D2VM50 Predicted protein n=1 Tax=Naegleria gruberi RepI...   110   7e-23
UniRef50_Q2RWF2 Nitrilase/cyanide hydratase and apolipoprotein N...   108   2e-22
UniRef50_C1GYG0 Hydrolase n=1 Tax=Paracoccidioides brasiliensis ...   108   2e-22
UniRef50_Q1LEX6 Nitrilase/cyanide hydratase and apolipoprotein N...   108   2e-22
UniRef50_A5G317 Nitrilase/cyanide hydratase and apolipoprotein N...   107   3e-22
UniRef50_B5JWE9 Nitrilase/cyanide hydratase and apolipoprotein N...   107   3e-22
UniRef50_B0TEY4 Hydrolase, carbon-nitrogen family n=1 Tax=Heliob...   107   3e-22
UniRef50_C8S929 Nitrilase/cyanide hydratase and apolipoprotein N...   107   3e-22
UniRef50_C7LN61 Nitrilase/cyanide hydratase and apolipoprotein N...   106   6e-22
UniRef50_A6UCF8 Nitrilase/cyanide hydratase and apolipoprotein N...   106   8e-22
UniRef50_A3CTE8 Nitrilase/cyanide hydratase and apolipoprotein N...   106   9e-22
UniRef50_A1HPP3 Nitrilase/cyanide hydratase and apolipoprotein N...   105   1e-21
UniRef50_Q28IE5 Omega-amidase NIT2 n=42 Tax=cellular organisms R...   105   2e-21
UniRef50_Q220F6 Nitrilase/cyanide hydratase and apolipoprotein N...   105   2e-21
UniRef50_A7I641 Nitrilase/cyanide hydratase and apolipoprotein N...   105   2e-21
UniRef50_Q2JDM2 Nitrilase/cyanide hydratase and apolipoprotein N...   105   2e-21
UniRef50_D0LZ94 Nitrilase/cyanide hydratase and apolipoprotein N...   104   2e-21
UniRef50_Q54JM9 Nitrilase homolog 2 n=1 Tax=Dictyostelium discoi...   104   3e-21
UniRef50_C8NJS3 Carbon-nitrogen hydrolase family protein n=16 Ta...   104   3e-21
UniRef50_A1SU00 Nitrilase/cyanide hydratase and apolipoprotein N...   104   3e-21
UniRef50_Q0AX54 N-carbamoyl-D-amino acid amidohydrolase n=3 Tax=...   103   4e-21
UniRef50_A3ZLM3 Putative nitrilase n=1 Tax=Blastopirellula marin...   103   4e-21
UniRef50_Q3IFH8 Putative hydrolase, carbon-nitrogen family n=3 T...   103   5e-21
UniRef50_Q47VH0 Hydrolase, carbon-nitrogen family n=1 Tax=Colwel...   103   5e-21
UniRef50_Q9KE11 BH1047 protein n=2 Tax=Bacillaceae RepID=Q9KE11_...   103   5e-21
UniRef50_Q6BU62 DEHA2C13310p n=6 Tax=Saccharomycetales RepID=Q6B...   103   6e-21
UniRef50_A0BR54 Chromosome undetermined scaffold_122, whole geno...   103   6e-21
UniRef50_C6N396 Nitrilase n=2 Tax=Legionella RepID=C6N396_9GAMM       103   7e-21
UniRef50_Q9NQR4 Omega-amidase NIT2 n=88 Tax=Eukaryota RepID=NIT2...   103   7e-21
UniRef50_C0VX65 Nitrilase/cyanide hydratase and apolipoprotein N...   103   8e-21
UniRef50_A8RJL1 Putative uncharacterized protein n=1 Tax=Clostri...   102   9e-21
UniRef50_Q0VS65 Carbon-nitrogen hydrolase family protein n=2 Tax...   102   9e-21
UniRef50_B2SXB2 Nitrilase/cyanide hydratase and apolipoprotein N...   102   1e-20
UniRef50_D2RS34 Nitrilase/cyanide hydratase and apolipoprotein N...   102   1e-20
UniRef50_D0RND5 Hydrolase n=1 Tax=alpha proteobacterium HIMB114 ...   102   1e-20
UniRef50_Q15ZG7 Nitrilase/cyanide hydratase and apolipoprotein N...   102   1e-20
UniRef50_A4XQL4 Nitrilase/cyanide hydratase and apolipoprotein N...   102   2e-20
UniRef50_C8VW38 Nitrilase/cyanide hydratase and apolipoprotein N...   102   2e-20
UniRef50_Q1AWK1 Nitrilase/cyanide hydratase and apolipoprotein N...   101   2e-20
UniRef50_A4SSL0 Beta-ureidopropionase n=2 Tax=Gammaproteobacteri...   101   2e-20
UniRef50_B7Q2J6 Carbon-nitrogen hydrolase, putative n=1 Tax=Ixod...   101   2e-20
UniRef50_A1RVM3 Nitrilase/cyanide hydratase and apolipoprotein N...   101   2e-20
UniRef50_C5RGI3 Nitrilase/cyanide hydratase and apolipoprotein N...   101   2e-20
UniRef50_B4D6H9 Nitrilase/cyanide hydratase and apolipoprotein N...   101   2e-20
UniRef50_B4RQA3 Nitrilase n=28 Tax=Neisseriaceae RepID=B4RQA3_NEIG2   101   3e-20
UniRef50_A7GE66 Hydrolase, carbon-nitrogen family n=24 Tax=cellu...   100   4e-20
UniRef50_A0L7H1 Nitrilase/cyanide hydratase and apolipoprotein N...   100   4e-20
UniRef50_A6F4Z1 Predicted amidohydrolase n=2 Tax=Marinobacter Re...   100   4e-20
UniRef50_Q94JV5 AT4g08790/T32A17_100 n=10 Tax=Viridiplantae RepI...   100   6e-20
UniRef50_C4R2Y9 Nit protein n=1 Tax=Pichia pastoris GS115 RepID=...   100   6e-20
UniRef50_Q12ZA5 Carbon-nitrogen hydrolase family protein n=1 Tax...   100   8e-20
UniRef50_A5N8H1 Predicted hydrolase n=3 Tax=Clostridium RepID=A5...   100   9e-20
UniRef50_A0LQU6 Nitrilase/cyanide hydratase and apolipoprotein N...   100   9e-20
UniRef50_C9KQR5 Hydrolase, carbon-nitrogen family n=1 Tax=Mitsuo...    99   1e-19
UniRef50_Q9LE50 Nitrilase 1 like protein n=2 Tax=Viridiplantae R...    99   1e-19
UniRef50_A8Q4Q4 Putative uncharacterized protein n=1 Tax=Malasse...    99   1e-19
UniRef50_Q65KK0 Methylthioribose recycling protein n=1 Tax=Bacil...    99   1e-19
UniRef50_O31664 UPF0012 hydrolase mtnU n=96 Tax=Bacilli RepID=MT...    99   1e-19
UniRef50_B7G2G6 Predicted protein n=1 Tax=Phaeodactylum tricornu...    98   2e-19
UniRef50_Q0S9Y1 Possible nitrilase n=3 Tax=Actinomycetales RepID...    98   2e-19
UniRef50_A3WPW5 Predicted amidohydrolase, nitrilase family proti...    98   3e-19
UniRef50_A9UWV2 Predicted protein (Fragment) n=1 Tax=Monosiga br...    97   4e-19
UniRef50_Q7QKM8 AGAP012662-PA (Fragment) n=14 Tax=Neoptera RepID...    97   4e-19
UniRef50_B9JB81 Amidohydrolase protein n=4 Tax=cellular organism...    97   4e-19
UniRef50_C7ICC9 Nitrilase/cyanide hydratase and apolipoprotein N...    97   5e-19
UniRef50_B4IMX5 GM23937 n=3 Tax=Drosophila sechellia RepID=B4IMX...    97   7e-19
UniRef50_Q28TG7 Nitrilase/cyanide hydratase and apolipoprotein N...    97   7e-19
UniRef50_C6JLR5 Nitrilase/cyanide hydratase and apolipoprotein N...    96   1e-18
UniRef50_Q8RUF8 AT5g12040/F14F18_210 n=16 Tax=Eukaryota RepID=Q8...    96   1e-18
UniRef50_Q0F1V1 Hydrolase, carbon-nitrogen family protein n=1 Ta...    96   1e-18
UniRef50_C1SGV5 Predicted amidohydrolase n=1 Tax=Denitrovibrio a...    96   1e-18
UniRef50_C0GEE7 Nitrilase/cyanide hydratase and apolipoprotein N...    96   1e-18
UniRef50_B6K212 UPF0012 hydrolase n=1 Tax=Schizosaccharomyces ja...    96   1e-18
UniRef50_A8PU96 Putative uncharacterized protein n=1 Tax=Malasse...    96   1e-18
UniRef50_A3SP65 Possible nitrilase n=2 Tax=Rhodobacteraceae RepI...    96   2e-18
UniRef50_Q5WM18 Methylthioribose recycling protein n=3 Tax=Bacil...    96   2e-18
UniRef50_Q6SHH5 Carbon-nitrogen hydrolase family protein n=2 Tax...    96   2e-18
UniRef50_Q97IH6 Predicted amidohydrolase n=1 Tax=Clostridium ace...    95   2e-18
UniRef50_C1XNR0 Predicted amidohydrolase n=2 Tax=Meiothermus Rep...    95   2e-18
UniRef50_C7MFL6 Predicted amidohydrolase n=1 Tax=Brachybacterium...    95   2e-18
UniRef50_C7YHV7 Putative uncharacterized protein n=2 Tax=Nectria...    95   3e-18
UniRef50_B9CT99 Hydrolase in agr operon (ORF 5) n=2 Tax=Staphylo...    94   3e-18
UniRef50_Q5UF08 Predicted amidohydrolase n=1 Tax=uncultured alph...    94   3e-18
UniRef50_D2RK67 Nitrilase/cyanide hydratase and apolipoprotein N...    94   4e-18
UniRef50_A8I529 Carbon-nitrogen hydrolase family protein n=8 Tax...    94   4e-18
UniRef50_A5VIE2 Nitrilase/cyanide hydratase and apolipoprotein N...    94   6e-18
UniRef50_O76464 Nitrilase homolog n=6 Tax=Sophophora RepID=NFT1_...    94   6e-18
UniRef50_Q2NAB0 Nitrilase 1 like protein n=3 Tax=Sphingomonadale...    93   7e-18
UniRef50_A4BGL8 Predicted amidohydrolase n=1 Tax=Reinekea blande...    93   8e-18
UniRef50_A3DL17 Nitrilase/cyanide hydratase and apolipoprotein N...    93   8e-18
UniRef50_C6B8T0 Nitrilase/cyanide hydratase and apolipoprotein N...    93   1e-17
UniRef50_B2HTJ8 Predicted amidohydrolase n=18 Tax=Acinetobacter ...    92   1e-17
UniRef50_Q7MHE3 Predicted amidohydrolase n=69 Tax=Proteobacteria...    92   2e-17
UniRef50_C4QCM8 Nitrilase-related n=1 Tax=Schistosoma mansoni Re...    92   2e-17
UniRef50_C2BXL2 Cyanide hydratase n=1 Tax=Listeria grayi DSM 206...    92   2e-17
UniRef50_Q3SLE9 Carbon-nitrogen hydrolase n=101 Tax=Proteobacter...    91   3e-17
UniRef50_A8ZSH3 Nitrilase/cyanide hydratase and apolipoprotein N...    91   4e-17
UniRef50_A8VU18 Amidohydrolase-like protein n=1 Tax=Bacillus sel...    91   4e-17
UniRef50_C0F0M8 Putative uncharacterized protein n=1 Tax=Eubacte...    91   5e-17
UniRef50_C7QHA6 Nitrilase/cyanide hydratase and apolipoprotein N...    91   6e-17
UniRef50_B9HD27 Predicted protein n=8 Tax=Magnoliophyta RepID=B9...    90   7e-17
UniRef50_A6DKQ0 Carbon-nitrogen hydrolase family protein n=1 Tax...    90   7e-17
UniRef50_C7TF35 Hydrolase, carbon-nitrogen family n=17 Tax=Lacto...    90   8e-17
UniRef50_A1SMV4 Nitrilase/cyanide hydratase and apolipoprotein N...    90   9e-17
UniRef50_Q6AMZ4 Putative uncharacterized protein n=1 Tax=Desulfo...    90   1e-16
UniRef50_A8MG18 Nitrilase/cyanide hydratase and apolipoprotein N...    89   1e-16
UniRef50_A7FDR9 Hydrolase, carbon-nitrogen family protein n=45 T...    89   1e-16
UniRef50_Q46AW4 Putative amidohydrolase n=1 Tax=Methanosarcina b...    89   1e-16
UniRef50_Q6MPB5 Putative amidohydrolase n=1 Tax=Bdellovibrio bac...    89   1e-16
UniRef50_C9N4S0 Nitrilase/cyanide hydratase and apolipoprotein N...    89   1e-16
UniRef50_Q5KLT5 Nitrilase-like protein, putative n=2 Tax=Filobas...    89   1e-16
UniRef50_C0D6C3 Putative uncharacterized protein n=1 Tax=Clostri...    89   1e-16
UniRef50_Q724C2 Hydrolase, carbon-nitrogen family n=20 Tax=Bacil...    89   1e-16
UniRef50_A1SE99 Nitrilase/cyanide hydratase and apolipoprotein N...    89   2e-16
UniRef50_D0XIR2 Nitrilase/cyanide hydratase and apolipoprotein N...    89   2e-16
UniRef50_B1I274 Nitrilase/cyanide hydratase and apolipoprotein N...    88   2e-16
UniRef50_Q5DC61 SJCHGC06938 protein n=1 Tax=Schistosoma japonicu...    88   2e-16
UniRef50_A1WYY7 Nitrilase/cyanide hydratase and apolipoprotein N...    88   3e-16
UniRef50_A8MC40 Nitrilase/cyanide hydratase and apolipoprotein N...    88   3e-16
UniRef50_A1HQ26 Nitrilase/cyanide hydratase and apolipoprotein N...    87   5e-16
UniRef50_C4XZI3 Putative uncharacterized protein n=1 Tax=Clavisp...    87   5e-16
UniRef50_A0BLB1 Chromosome undetermined scaffold_114, whole geno...    87   5e-16
UniRef50_C4QU15 Nitrilase-related (Fragment) n=2 Tax=Schistosoma...    87   5e-16
UniRef50_A0JTY0 Nitrilase/cyanide hydratase and apolipoprotein N...    87   6e-16
UniRef50_Q2BKP4 Putative carbon-nitrogen hydrolase n=1 Tax=Neptu...    87   6e-16
UniRef50_A0LH50 Nitrilase/cyanide hydratase and apolipoprotein N...    87   7e-16
UniRef50_C7GZE3 Nitrilase protein n=1 Tax=Eubacterium saphenum A...    87   7e-16
UniRef50_A6TPX2 Nitrilase/cyanide hydratase and apolipoprotein N...    87   8e-16
UniRef50_Q2G6S2 Nitrilase/cyanide hydratase and apolipoprotein N...    87   8e-16
UniRef50_C2D0V8 Possible N-carbamoylputrescine amidase n=1 Tax=L...    86   9e-16
UniRef50_A8UWC0 Putative uncharacterized protein n=2 Tax=Aquific...    86   1e-15
UniRef50_A4S5E0 Predicted protein n=2 Tax=Ostreococcus RepID=A4S...    86   1e-15
UniRef50_C1E770 Predicted protein (Fragment) n=1 Tax=Micromonas ...    86   1e-15
UniRef50_Q1YU23 Hydrolase, carbon-nitrogen family protein n=1 Ta...    86   1e-15
UniRef50_UPI000174507F Amidohydrolase n=1 Tax=Verrucomicrobium s...    86   1e-15
UniRef50_Q1MYM0 Predicted amidohydrolase n=1 Tax=Bermanella mari...    86   1e-15
UniRef50_UPI0000E105FE putative hydrolase, carbon-nitrogen famil...    86   2e-15
UniRef50_D2B8M8 Nitrilase/cyanide hydratase and apolipoprotein N...    85   2e-15
UniRef50_A9B254 Nitrilase/cyanide hydratase and apolipoprotein N...    85   2e-15
UniRef50_A2FF61 Hydrolase NIT3, putative n=4 Tax=cellular organi...    85   2e-15
UniRef50_C5SMM5 Nitrilase/cyanide hydratase and apolipoprotein N...    85   2e-15
UniRef50_C7R9G8 Nitrilase/cyanide hydratase and apolipoprotein N...    85   2e-15
UniRef50_B8C1M9 Nitrilase n=1 Tax=Thalassiosira pseudonana RepID...    85   2e-15
UniRef50_C8PV21 Putative hydrolase Nit2 n=1 Tax=Enhydrobacter ae...    85   2e-15
UniRef50_Q972X1 264aa long hypothetical beta-ureidopropionase n=...    85   3e-15
UniRef50_C9XNA8 Putative carbon-nitrogen hydrolase n=6 Tax=Clost...    85   3e-15
UniRef50_A6DN63 Nitrilase/cyanide hydratase and apolipoprotein N...    85   3e-15
UniRef50_B7CB92 Putative uncharacterized protein n=1 Tax=Eubacte...    84   5e-15
UniRef50_D2RHR5 Nitrilase/cyanide hydratase and apolipoprotein N...    83   9e-15
UniRef50_A8ZTL1 Nitrilase/cyanide hydratase and apolipoprotein N...    83   9e-15
UniRef50_B2TQP4 Nitrilase/cyanide hydratase and apolipoprotein N...    83   1e-14
UniRef50_A5TTZ3 Possible amidohydrolase n=4 Tax=Fusobacterium Re...    83   1e-14
UniRef50_B8FEV8 Nitrilase/cyanide hydratase and apolipoprotein N...    83   1e-14
UniRef50_A5FWH4 Nitrilase/cyanide hydratase and apolipoprotein N...    82   1e-14
UniRef50_Q5B724 Putative uncharacterized protein n=1 Tax=Emerice...    82   2e-14
UniRef50_C7NGT1 Predicted amidohydrolase n=1 Tax=Kytococcus sede...    82   2e-14
UniRef50_Q9ZMC7 Putative n=14 Tax=Helicobacter RepID=Q9ZMC7_HELPJ      82   2e-14
UniRef50_B1MWQ8 Predicted amidohydrolase n=5 Tax=Lactobacillales...    82   2e-14
UniRef50_A5GU42 Nitrilase-related protein n=1 Tax=Synechococcus ...    82   2e-14
UniRef50_Q4P4D1 Putative uncharacterized protein n=1 Tax=Ustilag...    82   2e-14
UniRef50_Q5KJU9 Hydrolase, putative n=1 Tax=Filobasidiella neofo...    82   3e-14
UniRef50_Q8TLM7 Carbon-nitrogen hydrolase n=2 Tax=Methanosarcina...    82   3e-14
UniRef50_B4MBJ2 GJ14457 n=5 Tax=Drosophila RepID=B4MBJ2_DROVI          81   3e-14
UniRef50_Q2TYD8 Carbon-nitrogen hydrolase n=1 Tax=Aspergillus or...    81   4e-14
UniRef50_C5BSY0 Hydrolase, carbon-nitrogen family n=1 Tax=Teredi...    80   5e-14
UniRef50_P55176 UPF0012 hydrolase in pqqF 5'region n=22 Tax=Bact...    80   5e-14
UniRef50_C4MAX0 Hydrolase yafV, putative n=2 Tax=Entamoeba RepID...    80   5e-14
UniRef50_A8LPZ9 Nitrilase/cyanide hydratase and apolipoprotein N...    80   5e-14
UniRef50_B0X5I4 Hydrolase n=5 Tax=Culicidae RepID=B0X5I4_CULQU         80   6e-14
UniRef50_Q30T00 Nitrilase/cyanide hydratase and apolipoprotein N...    80   7e-14
UniRef50_B6B254 Hydrolase in PqqF 5'region n=1 Tax=Rhodobacteral...    80   1e-13
UniRef50_A4SNH5 Amidohydrolase family protein n=2 Tax=Proteobact...    79   2e-13
UniRef50_UPI0001BC35FB amidohydrolase n=1 Tax=Butyrivibrio cross...    79   2e-13
UniRef50_A6LLW0 Nitrilase/cyanide hydratase and apolipoprotein N...    79   2e-13
UniRef50_D1BL17 Nitrilase/cyanide hydratase and apolipoprotein N...    78   3e-13
UniRef50_C5L8W7 Putative uncharacterized protein n=2 Tax=Perkins...    78   3e-13

>UniRef50_P58054 UPF0012 hydrolase ybeM n=121 Tax=Proteobacteria RepID=YBEM_ECO57
          Length = 262

 Score =  531 bits (1369), Expect = e-150,   Method: Compositional matrix adjust.
 Identities = 260/262 (99%), Positives = 260/262 (99%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           MLVAAGQFAVTSVWEKNAEICASLMAQAAEND SLF LPEALLARDDHDADLSVKSAQLL
Sbjct: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLL 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ
Sbjct: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE
Sbjct: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
           HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
Sbjct: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240

Query: 241 VRQVRAQLPVLNNRRFAPPQLL 262
           VRQVRAQLPVLNNRRFAPPQLL
Sbjct: 241 VRQVRAQLPVLNNRRFAPPQLL 262


>UniRef50_UPI00019771AF Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Bifidobacterium bifidum NCIMB 41171
           RepID=UPI00019771AF
          Length = 296

 Score =  217 bits (552), Expect = 4e-55,   Method: Compositional matrix adjust.
 Identities = 122/286 (42%), Positives = 164/286 (57%), Gaps = 27/286 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  QF V    E N +I      QAA+  A L  LPE L+ARD  D   +   AQ L+G
Sbjct: 9   VAVAQFTVRREPEWNLDIIDGYAWQAADAGARLLVLPEGLIARDGDDDMFAAAHAQPLDG 68

Query: 63  EFLGRLRRESKRNMMTTILTIH--------VPSTP------GRAWNMLVALQAGNIVARY 108
            F   LRR S+   +T + T+H        VP  P       R  N+ V +  G ++A Y
Sbjct: 69  PFATGLRRISEERHITLMGTVHAVPGAADAVPDKPASCATDSRVSNVFVVIHDGALIATY 128

Query: 109 AKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
            KLHLYDAFA +ES  V +G E+ P++E++G  VG+MTCYD+RFPE+A + A++GA++++
Sbjct: 129 RKLHLYDAFAARESDTVRSGTELPPIVEIDGWHVGVMTCYDVRFPEVARSLAVRGADVII 188

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASE- 227
           + AAWVRG LKE HW  + AARAL+ TCY++A  E   +NIG SR IDP G  IA A + 
Sbjct: 189 VSAAWVRGRLKERHWKLMTAARALENTCYVLACSEVSARNIGCSRAIDPLGEVIAQAGDG 248

Query: 228 ------------MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
                          +++A +  E +   R  LPVL NRRFA PQL
Sbjct: 249 QGWLCGQGEAGGQAGMLIARLHREVLESARRTLPVLENRRFADPQL 294


>UniRef50_A7A823 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=A7A823_BIFAD
          Length = 277

 Score =  214 bits (544), Expect = 3e-54,   Method: Compositional matrix adjust.
 Identities = 108/258 (41%), Positives = 153/258 (59%), Gaps = 1/258 (0%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M VA GQF VT   E N  I +   ++AA N   +  LPE L+AR D D   +   AQ +
Sbjct: 19  MKVAVGQFTVTEKPEHNINIISGFASEAARNHTRILLLPEGLIARSDDDPHYTADHAQTI 78

Query: 61  EGEFLGRLRRESKRNMMTTILTIHV-PSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           +G F+  LR  S+ N +  + T+H+   T    +N  + +  G I+  Y K+HLYDAF  
Sbjct: 79  DGPFVTALRGISEANNIAVMGTVHLHEDTVDLPYNCFLVIDHGRILLEYRKIHLYDAFGE 138

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +ES  +  G+E+ PL++++G K G+MTCYD+RFPELA   A+ GA+ LV+ AAW RG  K
Sbjct: 139 RESDSIAPGHEVPPLVDIDGWKFGVMTCYDIRFPELARRHAVAGADALVVSAAWARGEGK 198

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
             HW+TL  ARAL+ TCY++A  E    +IG S ++DP    +A + E   LI A++  +
Sbjct: 199 VDHWTTLCKARALENTCYLMACSEHSGHDIGHSMVVDPAARILAQSGERDELIYADLNRD 258

Query: 240 RVRQVRAQLPVLNNRRFA 257
           R+  VR  LPVL NRR  
Sbjct: 259 RLEDVRRILPVLKNRRIT 276


>UniRef50_A9WV78 Hydrolase, carbon-nitrogen family n=3 Tax=Micrococcaceae
           RepID=A9WV78_RENSM
          Length = 268

 Score =  172 bits (437), Expect = 9e-42,   Method: Compositional matrix adjust.
 Identities = 108/266 (40%), Positives = 147/266 (55%), Gaps = 20/266 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLA---------RDDHDAD 51
           M V+ GQF+     + N E    L A+AA++ + L   PE  +          R   DA 
Sbjct: 1   MKVSVGQFSPVGDVDGNIEAMRRLAAEAAQDGSELILFPEEAMFTLGKVAGDFRSAVDAG 60

Query: 52  LSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAK 110
            SV         F+ +L   +  + +  I   +  S   R +N LVA+ + G I+  Y K
Sbjct: 61  WSV---------FVQQLTLIAAEHKIAIIAGGYESSGEERPFNTLVAVGSDGAILGTYRK 111

Query: 111 LHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
           LHLYDAF+ QES+R+  GN    ++ V  + VG+MTCYDLRFPELA A A Q  +++ +P
Sbjct: 112 LHLYDAFSYQESKRIMPGNSGLTVVRVGELNVGMMTCYDLRFPELARALAEQDVDLICVP 171

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMP- 229
           AAW +G  K  HW TLL ARA++ TC++ AAG      IG S I+DP GV  A   E P 
Sbjct: 172 AAWFKGEHKVDHWETLLKARAIENTCWVAAAGSMSPHCIGHSVILDPMGVPAAFLDEEPE 231

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRR 255
           +L  AEVT +R+ +VR  LPVL NRR
Sbjct: 232 SLATAEVTVKRIEEVREFLPVLKNRR 257


>UniRef50_Q0S3S2 Possible amidohydrolase, carbon-nitrogen hydrolase family protein
           n=11 Tax=Actinomycetales RepID=Q0S3S2_RHOSR
          Length = 265

 Score =  171 bits (434), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 105/263 (39%), Positives = 147/263 (55%), Gaps = 5/263 (1%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  QFA     ++N     +L A+AA   A +   PE  +       +  V+SA+ L+G
Sbjct: 4   VAVIQFAPGQDKQENLRTLRTLAAEAAGRGAKVVVAPEYAMFTAPRTDERIVESAEGLDG 63

Query: 63  EFLGRLRRESKRNMMTTILTI--HVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
           EF+  L   +K   +  +  +  H+P       N +VAL   G+IVA Y KLHLYDAF  
Sbjct: 64  EFVSGLAATAKELDVHLVAGVNEHLPGDD-HISNTIVALGPGGDIVATYRKLHLYDAFGY 122

Query: 120 QESRRVDAGNEIAP-LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           +ES  + AG   AP    V+G+  G+ TCYDLRFPE+       GA++L+LPA WV GPL
Sbjct: 123 KESDVIRAGEIDAPQTFAVDGLTFGMQTCYDLRFPEVTRRIVDAGADVLLLPAQWVPGPL 182

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           KE HWSTL+ ARA++ T Y+ AA +      G S I+DP GVT+A+  E     +A V+ 
Sbjct: 183 KEDHWSTLVRARAIENTVYVAAADQSARTGAGNSMIVDPMGVTLASLGERVGTAVAAVSA 242

Query: 239 ERVRQVRAQLPVLNNRRFAPPQL 261
           ER+ +VR + P L  RRF   ++
Sbjct: 243 ERITEVREKNPALALRRFTVSEI 265


>UniRef50_UPI000197C0D6 hypothetical protein PretD1_21713 n=1 Tax=Providencia rettgeri DSM
           1131 RepID=UPI000197C0D6
          Length = 263

 Score =  169 bits (428), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 95/260 (36%), Positives = 150/260 (57%), Gaps = 6/260 (2%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKS-AQL 59
           M +A  Q A +     N +     + +AA+  A L  LPE  +A    D+ +S    A+ 
Sbjct: 1   MKIAIAQLASSPDKALNLKKACEAIQKAAQGGADLVLLPEMFMAFVPADSGISYADVAEP 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIH--VPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDA 116
           ++G F+ +L + +++  +     I+   P+ P RA+N  + L + G ++  Y K HLYDA
Sbjct: 61  VDGPFVSQLAKAAQQYGIYVTCGIYESAPNEPKRAFNTTIMLNRQGELIYHYQKTHLYDA 120

Query: 117 FAIQESRRV-DAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
           F+ QES  +  + NE+ P+ E E  K+G++ CY+LRFPE+A    L GA+++++P AWV 
Sbjct: 121 FSYQESLNIIQSNNELKPV-ETEFGKIGVLVCYELRFPEVARKLTLAGADLILVPTAWVS 179

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAE 235
           GPLKE H+ TL+ ARAL+ T  + A  + GN  IG+S + D  GVTIA+A     L  AE
Sbjct: 180 GPLKEEHYQTLVKARALENTVPVCACDQTGNIFIGRSLVCDALGVTIASAGYDETLFFAE 239

Query: 236 VTPERVRQVRAQLPVLNNRR 255
           ++ +   + R +LP + NRR
Sbjct: 240 ISTQHTAETREKLPCMQNRR 259


>UniRef50_A9A651 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Thaumarchaeota RepID=A9A651_NITMS
          Length = 268

 Score =  165 bits (417), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 83/259 (32%), Positives = 144/259 (55%), Gaps = 4/259 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALL--ARDDHDADLSVKSAQ 58
           M  A  QF  ++  E N +   S + +AA  +A+L A PE ++               A+
Sbjct: 1   MKAAVVQFKASTNKETNLKKIISFIEKAASKNATLCAFPEFMMFYTNSSQTPKQLATLAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNM-LVALQAGNIVARYAKLHLYDA 116
            + G F+  +   +K N +  + + +  S    R ++   V  + G +++ Y K+HLYDA
Sbjct: 61  TINGNFVNTIANTAKENHVQVVGSFYEKSRKKDRVYDTSFVIDKTGKVISTYRKIHLYDA 120

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
              +ES ++ +G++IA  ++    KVG+M CYDLRFPE++ + A  G+E+LV P+AWV+G
Sbjct: 121 LGFRESDKMASGSKIAKPVKTTIGKVGMMICYDLRFPEMSRSLAAAGSEVLVAPSAWVKG 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
            +KE HW T+   RA++  CY++A  + GN   G+S ++DP+G  +    +   +    +
Sbjct: 181 NMKEEHWITINKTRAIENGCYVIAPDQVGNIYCGRSLVVDPYGKILLDMKKKQGIGYVNI 240

Query: 237 TPERVRQVRAQLPVLNNRR 255
             ++V+Q+R  LP+L NRR
Sbjct: 241 DLKKVKQIRKVLPLLKNRR 259


>UniRef50_C0Z4R2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z4R2_BREBN
          Length = 265

 Score =  164 bits (416), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 95/259 (36%), Positives = 144/259 (55%), Gaps = 4/259 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLS-VKSAQL 59
           M VA  Q   T    +N +  A  +A+A    A    LPE   A     + ++  + A+ 
Sbjct: 1   MKVAIAQLTATMDKTQNLQKAADYIAKAKAAGADFVILPEMYSAPATPKSGVTPAEVAEK 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIH--VPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDA 116
           L+G F+  L   +  + +  +  +   +     RA+N  V L + G ++  Y K HLYDA
Sbjct: 61  LDGPFVSGLAELASEHGVYVVCGVFESIEGDENRAYNTTVFLGREGQLLHAYRKTHLYDA 120

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
           F+  ES  +  G+    ++E E  K+GLM CY++RFPE+A   ALQGA+IL +PA WV G
Sbjct: 121 FSYTESDFIAPGDNPYQVVETEFGKIGLMVCYEVRFPEIARQFALQGADILFVPAGWVAG 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
            +KE HW TL+ ARA++ T ++ AA + GN   G+S  +DP GV IA+A E   L++ E+
Sbjct: 181 AMKEDHWETLVRARAIENTMFVCAADQVGNIFAGRSMFVDPMGVVIASAGEEETLLVTEL 240

Query: 237 TPERVRQVRAQLPVLNNRR 255
              R+ +VR +LP + NRR
Sbjct: 241 DVSRIERVRGKLPSVANRR 259


>UniRef50_C4DVK2 Predicted amidohydrolase n=1 Tax=Stackebrandtia nassauensis DSM
           44728 RepID=C4DVK2_9ACTO
          Length = 272

 Score =  160 bits (406), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 86/242 (35%), Positives = 134/242 (55%), Gaps = 3/242 (1%)

Query: 16  KNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRN 75
           +N   C   + +A      L   PE + +R D  +      A+ L+  F+  L + ++  
Sbjct: 22  ENLRQCLRYLDEARTAGVDLLIFPETVSSRVDDPS--RAPQAESLDDGFVAGLAKATEGL 79

Query: 76  MMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLL 135
            +T I  +   +   R +N LVAL+ G  VARY K+HLYDA A+ ES  +  G+      
Sbjct: 80  DLTVIAGV-TETHDDRPFNTLVALRDGQRVARYRKIHLYDACAMAESDTIAPGDGPVSTF 138

Query: 136 EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTT 195
            V+G +VG+MTCYD+RFPEL+   A +GA++L +P +WVRGPLKE HW+T   ARAL+ T
Sbjct: 139 AVKGFEVGMMTCYDIRFPELSRLLAERGADLLAVPTSWVRGPLKEEHWTTFCKARALENT 198

Query: 196 CYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            Y+  A + G   +G + ++ P GV ++  ++   L+ A +  + +   R   P+L  RR
Sbjct: 199 VYLAGACQTGGSRVGLTSVVAPDGVIVSRLAQHEGLVTARIGRDALTAAREAFPLLEQRR 258

Query: 256 FA 257
           FA
Sbjct: 259 FA 260


>UniRef50_D1BX77 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Actinomycetales RepID=D1BX77_XYLCX
          Length = 298

 Score =  157 bits (397), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 98/258 (37%), Positives = 139/258 (53%), Gaps = 6/258 (2%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q  V +    N +   +++  AA   A L  LPE   A       +  + A+ L+G
Sbjct: 34  VAIAQIEVGADHAANRDAVTAVVRDAAARGADLVVLPE--YASGFEPRGVGPEHAEPLDG 91

Query: 63  EFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQ 120
            F+  LR  ++ + +  +    +P   PGRA N +VA+ A G +   Y K+HLYDAF  +
Sbjct: 92  PFVSLLRALAREHGLAIVAGTTLPGEAPGRASNAIVAVGAQGELAGAYRKVHLYDAFGTR 151

Query: 121 ESRRVDAG-NEIAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           ES R++ G  + APL   V G+ VG++TCYDLRFPE A      GA+ ++ PAAWV GPL
Sbjct: 152 ESDRLEPGPADAAPLTFAVGGLTVGVLTCYDLRFPEAARRVVDAGAQAILYPAAWVAGPL 211

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K  HW TLL ARA++ T  +V  G  G    G+S ++D  GV +    E P L +A + P
Sbjct: 212 KADHWRTLLRARAIENTVAVVGVGMAGRTVTGRSLVVDADGVVVLELDETPQLAVATLDP 271

Query: 239 ERVRQVRAQLPVLNNRRF 256
               + RA  P L NRR+
Sbjct: 272 TATARTRAANPSLANRRY 289


>UniRef50_D1A7Y1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Streptosporangineae RepID=D1A7Y1_THECD
          Length = 261

 Score =  151 bits (382), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 96/251 (38%), Positives = 146/251 (58%), Gaps = 18/251 (7%)

Query: 16  KNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRN 75
           +N E     +A+A   D ++F  PEA+  R  +D       A+ LE  F G LR+ ++ +
Sbjct: 14  ENLEQVRRALARAEGADLAVF--PEAVPVRFGNDL---TAVAEPLEQGFAGELRKLAREH 68

Query: 76  MMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPL 134
               I  +  P+  GR +N  VA+ A G  V  Y K+HL+DAF  +ES RV  G+  AP+
Sbjct: 69  GTALIAGVFEPAGDGRVYNTAVAIDASGRPVGAYRKIHLFDAFGDRESARVAPGD--APV 126

Query: 135 L-EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALD 193
           + E+ G ++GL+TCYD+RFPELA A   +GA++LV+ AAW +G  KE HW+TL+ ARA++
Sbjct: 127 VVELAGARIGLITCYDVRFPELARALVDRGAQVLVIIAAWAQGVFKEEHWTTLVRARAIE 186

Query: 194 TTCYMVAAGECGNKN---------IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQV 244
            T ++VA  +  ++          +G+S +IDP G  +A     PA+ +AE+  E   +V
Sbjct: 187 NTTWVVAVDKAPDRTRPPEGGPGGVGRSMLIDPMGTVVADLGPFPAVRVAEIDQEVTERV 246

Query: 245 RAQLPVLNNRR 255
           R  LP L +RR
Sbjct: 247 RRILPSLQHRR 257


>UniRef50_A1SD43 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Nocardioides sp. JS614 RepID=A1SD43_NOCSJ
          Length = 261

 Score =  150 bits (380), Expect = 3e-35,   Method: Compositional matrix adjust.
 Identities = 93/236 (39%), Positives = 129/236 (54%), Gaps = 6/236 (2%)

Query: 24  LMAQAAENDASLFALPEALLARDDHDADLSVKS-AQLLEGEFLGRLRRESKRNMMTTILT 82
           L+ +     + L   PEA  ARD  DA   V + A+ L+G F   + R +     T +  
Sbjct: 29  LLGELTPAGSDLVVFPEAF-ARDFGDAGSDVSAYAESLDGPFATEVARVAADRGTTVVAG 87

Query: 83  I-HVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAG-NEIAPLLEVEGM 140
           +      P R +N LV   A    A Y K+HLYD+F  +ES R+ AG    A ++EV G 
Sbjct: 88  LFEAGEDPTRPFNTLVLRGAAE--ASYRKVHLYDSFGYRESDRLTAGPTGPAVVVEVGGF 145

Query: 141 KVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVA 200
           +VGLMTCYDLRFPELA      GA++LV+P+AWV GP K  HW TL+ ARA++ T ++ A
Sbjct: 146 RVGLMTCYDLRFPELARTLVDAGAQLLVVPSAWVAGPRKVDHWRTLVRARAIENTVFVAA 205

Query: 201 AGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            G+ G +  G S ++DP G  +  A +  A++ A V  E +   R   P L NRR 
Sbjct: 206 VGQPGPRYTGHSMVVDPLGDVLVEAGDEAAVVTATVDLEALAAARRTNPSLANRRL 261


>UniRef50_A4ALG5 Putative hydrolase n=1 Tax=marine actinobacterium PHSC20C1
           RepID=A4ALG5_9ACTN
          Length = 271

 Score =  150 bits (380), Expect = 4e-35,   Method: Compositional matrix adjust.
 Identities = 98/264 (37%), Positives = 136/264 (51%), Gaps = 15/264 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  QFA  +  ++N      L  +A E  A+    PE          D  + +A+ L+G
Sbjct: 7   VAVAQFAPGADRDENIATVTQLAERAVERGANFVVFPEYSAYFTPTMGDDWLAAAEPLDG 66

Query: 63  EFLGRLRRESKRNMMTTILTIHVPS-------TPGRAWNMLVALQ-AGNIVARYAKLHLY 114
            F+  L   ++R      L IHV +          R  N LVA+   G +VA Y K HLY
Sbjct: 67  PFVQALTSLAQR------LRIHVAAGMLESADEEKRFSNTLVAIAPTGAVVATYRKQHLY 120

Query: 115 DAFAIQESRRVDAGNEIAP-LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
           DAF  +ES  V  G+  AP     EG  VGL TCYD+RFPE++      GA ++V+PA W
Sbjct: 121 DAFGQRESDWVIPGSIGAPETFTWEGFTVGLQTCYDIRFPEVSRRLVDAGANLIVVPAEW 180

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIM 233
           VRGPLKE+HW TLL ARA++ T ++ AA       +G S ++DP GV +    E   + +
Sbjct: 181 VRGPLKEYHWRTLLTARAIENTIFVAAADHAPPIGVGHSMVVDPMGVELVTIGERTDVAV 240

Query: 234 AEVTPERVRQVRAQLPVLNNRRFA 257
           A +   R+ +VRA  P L  RR+ 
Sbjct: 241 AHIEHSRLDEVRAINPALELRRYG 264


>UniRef50_C1SI84 Predicted amidohydrolase n=1 Tax=Denitrovibrio acetiphilus DSM
           12809 RepID=C1SI84_9BACT
          Length = 259

 Score =  149 bits (377), Expect = 7e-35,   Method: Compositional matrix adjust.
 Identities = 89/256 (34%), Positives = 129/256 (50%), Gaps = 3/256 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M  AA Q  ++ + E+N E   SLM     +D  L  LPE ++       +L   +  + 
Sbjct: 1   MRAAAVQINLSGIKEQNLE--KSLMYIKKASDCDLVVLPEMVMGNRGDGVELYQLAEDVE 58

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAI 119
            G F   LR  + R  +     +   +   + +N  V   + G+I A+Y KLHL+DA + 
Sbjct: 59  TGSFASSLRNAAVRYQVDVCACLWEETGTEKVYNTAVVYGSDGSIKAKYRKLHLFDALSF 118

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            ES  +  G+E  P+ E  G+K GL  CYDLRFPE   +   +GAE+ ++PAAW  G LK
Sbjct: 119 TESDYMLRGSERPPVFESGGIKCGLSICYDLRFPETYRSLVKRGAELFIVPAAWYGGELK 178

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
             H  TLL  RAL+ TCY + A  CG    G S    PF    +A      L++ EV  +
Sbjct: 179 IEHLHTLLRTRALENTCYALTANLCGGNFSGYSVSFGPFAEECSALQNDEGLLVIEVDKK 238

Query: 240 RVRQVRAQLPVLNNRR 255
            + +VR++LP L N R
Sbjct: 239 HLSEVRSKLPCLENFR 254


>UniRef50_UPI000186DBB5 conserved hypothetical protein n=1 Tax=Pediculus humanus corporis
           RepID=UPI000186DBB5
          Length = 438

 Score =  143 bits (360), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 88/268 (32%), Positives = 142/268 (52%), Gaps = 15/268 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L+A  Q   T+  EKN +I  SL+ +A + +A +  LPEA        A+ ++  A+ L+
Sbjct: 6   LIAICQMTSTNDKEKNFQIVESLVTEAKKANAKIAFLPEACDFVGSSKAE-TITLAETLD 64

Query: 62  GEFLGRLRRESKR-NMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYDA--- 116
           G  + + +  +K   +  ++  IH   T  + +N  L+    GNIV +Y+K+HL+D    
Sbjct: 65  GPLVAKYKNLAKSLKIWISLGGIHESYTKSKLYNTHLMINDQGNIVGKYSKIHLFDVEIP 124

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                + ES  V+ G  I   +      VGL  CYD+RF EL++  A  GA+IL  P+A+
Sbjct: 125 EQNVRLMESSYVEKGKSITNPISTPVGNVGLAICYDMRFSELSIVLARLGAQILTFPSAF 184

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW T+L ARA++T CY+VAA + G+ N      G S ++DP+G  IA  S+ 
Sbjct: 185 TFAT-GASHWETILKARAVETQCYVVAAAQVGSHNDKRTSWGHSMVVDPWGKIIAQCSDG 243

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
           P + +  +    + +VR  +PV N+RR+
Sbjct: 244 PGIAVTSININYLEKVRLSMPVWNHRRY 271


>UniRef50_UPI0001B416B7 carbon-nitrogen hydrolase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI0001B416B7
          Length = 271

 Score =  141 bits (356), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 76/246 (30%), Positives = 127/246 (51%), Gaps = 8/246 (3%)

Query: 16  KNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRN 75
           +N E  A     AA N A L   PE  +    +  D  +++A++L G ++ R++  S+ N
Sbjct: 31  RNIEYYA---GTAAANSADLIVFPEYYMFYSQY-KDAIIRNAEVLNGNYIKRIKEISRTN 86

Query: 76  MMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLL 135
            +  I  I+        ++  V +  G ++  Y K HLYDAF  +ES     GN    + 
Sbjct: 87  KIGIITGIN-EVYDHNYYDTAVYVNDGELLNYYRKSHLYDAFGYRESDIYTYGNGPFKIS 145

Query: 136 EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTT 195
           ++  +  G++ CYD+RFPE+    +L  A++++L +AW  GP+KE  W +L++ RAL+ T
Sbjct: 146 KIGNINFGMLICYDIRFPEVFRNYSLNDADMVILISAWFAGPIKEEQWLSLVSTRALENT 205

Query: 196 CYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            Y+  +   G    G +   DP G  I  A+E   +I + +   R+  VR ++PVL  RR
Sbjct: 206 TYLATSNMIGGGFTGITTFTDPIGAIINRAAEDEDIIYSIIDTNRISTVRKKMPVLKQRR 265

Query: 256 FAPPQL 261
              P+L
Sbjct: 266 ---PEL 268


>UniRef50_A2BNC1 Predicted amidohydrolase n=1 Tax=Hyperthermus butylicus DSM 5456
           RepID=A2BNC1_HYPBU
          Length = 269

 Score =  138 bits (348), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 86/260 (33%), Positives = 138/260 (53%), Gaps = 5/260 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAE--NDASLFALPEALLARDDHDADLSVKS-A 57
           + +A  QF  T   E++ E    L+++     ++A L  +PE  +A        ++ + A
Sbjct: 4   LTIALLQFGATHSKEESLERIRKLISRYERIVSEADLLLVPEYSMADPTGQPPEAIAAIA 63

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA--GNIVARYAKLHLYD 115
           + LEG ++G   R ++   +  + T++  S  G       AL A  G ++A Y K+HL+D
Sbjct: 64  EPLEGPWIGFFARLAREYSVHVVATLYEKSKAGGKPYNTAALIAPTGELLAVYRKIHLFD 123

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
           A+  +ES     G E A L  ++G ++ L  C+DLRFPEL    ALQGAE++ +PAAW R
Sbjct: 124 AYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRFPELFRTYALQGAELVAVPAAWYR 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAE 235
           GP KE     + AARA + T Y+  A +  +   G+S + DP+G+ +  A     ++  E
Sbjct: 184 GPAKEDQLRIIAAARAHENTMYIAVASQYNSNFTGRSLVADPYGLVLLDAGRGEKIVQIE 243

Query: 236 VTPERVRQVRAQLPVLNNRR 255
           V  E + + R QLP+L  RR
Sbjct: 244 VDRESLEEARRQLPLLKLRR 263


>UniRef50_Q7TQ94 Nitrilase homolog 1 n=6 Tax=Coelomata RepID=NIT1_RAT
          Length = 292

 Score =  137 bits (346), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 96/277 (34%), Positives = 146/277 (52%), Gaps = 32/277 (11%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEAL--LARDDHDADLSVKSAQL 59
           LVA  Q   T   ++N + CA L+ +A    A L  LPEA   +AR+  +  L    ++ 
Sbjct: 13  LVAVCQVTSTPNKQENFKTCAELVQEATRLGACLAFLPEAFDFIARNPAETLLL---SEP 69

Query: 60  LEGEFLGRLRRESKR-NMMTTILTIHVPSTPGRAW-------NMLVALQA-GNIVARYAK 110
           L+G+ LG+  + ++   +  ++   H     G+ W       N  V L + G++VA Y K
Sbjct: 70  LDGDLLGQYSQLARECGIWLSLGGFH---ERGQDWEQTQKIYNCHVLLNSKGSVVASYRK 126

Query: 111 LHLYDA-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
            HL D        ++ES     G  + P ++    KVGL  CYD+RFPEL+L  A  GAE
Sbjct: 127 THLCDVEIPGQGPMRESNYTMPGYALEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAE 186

Query: 166 ILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPF 218
           IL  P+A+  V GP    HW  LL ARA+++ CY++AA +CG  +      G S ++DP+
Sbjct: 187 ILTYPSAFGSVTGPA---HWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPW 243

Query: 219 GVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G  +A+ SE P L +A +    ++Q+R  LPV  +RR
Sbjct: 244 GTVVASCSEGPGLCLARIDLHFLQQMRQHLPVFQHRR 280


>UniRef50_D1T004 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Acidovorax avenae subsp. avenae ATCC 19860
           RepID=D1T004_9BURK
          Length = 291

 Score =  137 bits (346), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 81/180 (45%), Positives = 108/180 (60%), Gaps = 19/180 (10%)

Query: 91  RAWN--MLVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVE--GMK 141
           R WN   LV+ + G +VARY KLH +D     A   QES  V  G     L+ ++  G+ 
Sbjct: 97  RVWNRSHLVSPE-GEVVARYDKLHTFDVELGGAGTFQESAAVRPGENGPTLVGIDALGLT 155

Query: 142 VGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMV 199
           +G+  CYDLRFP L    A  GA +L+ P+++  V GPL   HW TLL ARA++T  Y+V
Sbjct: 156 LGMSICYDLRFPHLYRCLAQAGANVLLAPSSFSVVTGPL---HWETLLKARAIETGSYVV 212

Query: 200 AAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           AA +CG ++     G SR+I PFG  IAAA + PA+I A++ PERVRQ R +LP L   R
Sbjct: 213 AAAQCGERDGVRVYGHSRVISPFGEVIAAAGDTPAIIYADIDPERVRQTRVRLPSLTRGR 272


>UniRef50_C7QZX4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Jonesia denitrificans DSM 20603
           RepID=C7QZX4_JONDD
          Length = 260

 Score =  136 bits (343), Expect = 6e-31,   Method: Compositional matrix adjust.
 Identities = 91/257 (35%), Positives = 127/257 (49%), Gaps = 4/257 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + V AGQ    +  E         +  A +    L  LPE     D     +   +A+ L
Sbjct: 7   LRVGAGQLMAAADHEVMRAQVRECLDDARDQGVDLLVLPEYSHYYDPRG--VPAHAAEPL 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +G F+  L R +    +T +  +  P+      N LV +  G + A Y K+HLYDAF  +
Sbjct: 65  DGPFVQLLARWTADASVTVVAGLTRPAHR-HPVNTLVVVAEGAVQATYDKVHLYDAFGYR 123

Query: 121 ESRRVDAGNEIAP-LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           ES  ++ G+     +  V    VGL TCYDLRFPEL   +   GA+I+V PAAWV GP K
Sbjct: 124 ESDHLEQGDVAQEGVFSVGEFSVGLQTCYDLRFPELTRRRIDAGADIVVNPAAWVAGPNK 183

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
            HHW TLLAARA++ T  MV A   G    G +RI+ P G T   A+    ++  EVT  
Sbjct: 184 LHHWRTLLAARAIENTVVMVGAALDGRGVCGDTRIVFPDGTTAVGAAHGRHVVSVEVTRT 243

Query: 240 RVRQVRAQLPVLNNRRF 256
            +   R + P L+NR +
Sbjct: 244 LIADARERNPSLSNRVY 260


>UniRef50_Q86X76 Nitrilase homolog 1 n=34 Tax=Eumetazoa RepID=NIT1_HUMAN
          Length = 327

 Score =  134 bits (338), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 100/279 (35%), Positives = 142/279 (50%), Gaps = 36/279 (12%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEAL--LARDDHDADLSVKSAQL 59
           LVA  Q   T   ++N + CA L+ +AA   A L  LPEA   +ARD  +   ++  ++ 
Sbjct: 48  LVAVCQVTSTPDKQQNFKTCAELVREAARLGACLAFLPEAFDFIARDPAE---TLHLSEP 104

Query: 60  LEGEFL---GRLRRESKRNMMTTILTIHVPSTPGRAW-------NMLVALQA-GNIVARY 108
           L G+ L    +L RE    +  ++   H     G+ W       N  V L + G +VA Y
Sbjct: 105 LGGKLLEEYTQLAREC--GLWLSLGGFH---ERGQDWEQTQKIYNCHVLLNSKGAVVATY 159

Query: 109 AKLHLYDA-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQG 163
            K HL D        + ES     G  +   +     K+GL  CYD+RFPEL+LA A  G
Sbjct: 160 RKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAG 219

Query: 164 AEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIID 216
           AEIL  P+A+  + GP    HW  LL ARA++T CY+VAA +CG  +      G S ++D
Sbjct: 220 AEILTYPSAFGSITGPA---HWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVD 276

Query: 217 PFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           P+G  +A  SE P L +A +    +RQ+R  LPV  +RR
Sbjct: 277 PWGTVVARCSEGPGLCLARIDLNYLRQLRRHLPVFQHRR 315


>UniRef50_UPI0001924654 PREDICTED: similar to Nit protein 1 n=1 Tax=Hydra magnipapillata
           RepID=UPI0001924654
          Length = 303

 Score =  134 bits (338), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 81/267 (30%), Positives = 139/267 (52%), Gaps = 15/267 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q   T   E+N  IC  L+ ++ + +A +  LPE      ++  D SVK A+ LEG
Sbjct: 28  VAVCQMNSTDDKERNIRICTELINESYDKEAKIVFLPECFDYIAENKTD-SVKMAESLEG 86

Query: 63  EFLGRLRRESK-RNMMTTILTIH--VPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
           + +   +  +K +++  ++   H    ++ G  +N  + + A G +V+ Y K+HL+D   
Sbjct: 87  DIIKHYKNLAKEKSLWLSMGGFHEKCSTSDGSIFNSHIIINANGELVSVYRKVHLFDVDI 146

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               ++ES  V  G +I   ++    K+GL+ CYDLRFPE+++     GA+IL  P+A+ 
Sbjct: 147 PGTVLKESSYVTPGKKIEKPVDTPVGKIGLLCCYDLRFPEISIVNRQLGAQILTFPSAFT 206

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMP 229
                  HW  LL ARA++  CY++AA + G  N      G + I+DP+G  +A   +  
Sbjct: 207 F-TTGLAHWHVLLRARAIENQCYVIAAAQTGKHNDKRTSYGHALIVDPWGKVVAECEKEN 265

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRF 256
            + +A +    V  +R  +PV  +RR+
Sbjct: 266 GVCVASIDLSLVDSIRESMPVFEHRRY 292


>UniRef50_UPI0000382451 COG0388: Predicted amidohydrolase n=1 Tax=Magnetospirillum
           magnetotacticum MS-1 RepID=UPI0000382451
          Length = 230

 Score =  134 bits (336), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 85/197 (43%), Positives = 118/197 (59%), Gaps = 6/197 (3%)

Query: 27  QAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVP 86
           +AA   A L  LPE   A D        + A+ L+G F+G LRR ++ + +  +    VP
Sbjct: 21  EAARVRADLLVLPEYAAAFDPRGT--GAEHAEPLDGPFVGTLRRLAREHGVAVVAGTLVP 78

Query: 87  -STPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIAP--LLEVEGMKV 142
            S PGRA N++VA+ A G++V  Y K+HLYDAF  +ES R+DAG+  AP  +L V  +  
Sbjct: 79  GSAPGRAVNVVVAVDAAGDLVGTYRKVHLYDAFGHRESDRLDAGDPAAPPLVLRVGDLTF 138

Query: 143 GLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAG 202
           G+MTCYDLRFPE A      GA++LV+PAAW  G LK   W TL  ARA++ T  ++A G
Sbjct: 139 GVMTCYDLRFPESARRLVDAGADVLVVPAAWAAGELKADQWRTLARARAIENTAVVLAVG 198

Query: 203 ECGNKNIGQSRIIDPFG 219
           + G    G+S ++ P G
Sbjct: 199 QAGRGVTGRSLLVGPDG 215


>UniRef50_Q702A9 Putative predicted amidohydrolase n=6 Tax=Archaea
           RepID=Q702A9_9CREN
          Length = 285

 Score =  133 bits (335), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 75/248 (30%), Positives = 128/248 (51%), Gaps = 7/248 (2%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARD--DHDADLSVKSAQLLEGEFLGRLRRES 72
           E N      L+ +AA+  A L   PE  +A    +   +   + A+ + G F+  L   +
Sbjct: 22  EHNLAYSVKLINEAAKRKARLICFPEFQMAYSPAEQKTESLHRIAEKICGNFVSTLSNSA 81

Query: 73  KRNMMTTILT----IHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYDAFAIQESRRVDA 127
           ++N +  I T    I+      + ++  ++  + G + + Y K+HLYDA   +ES+++ A
Sbjct: 82  RQNKINVIATMYEIINANEKSQKVFDTGIIINELGKVQSIYRKVHLYDALGFKESKKLLA 141

Query: 128 GNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLL 187
           G+ I    +     +GL+ CYD+RFPE++    + GA ILV P+AWV G +K+ HW  ++
Sbjct: 142 GSIIEKPSKTSVGNLGLLICYDMRFPEISRILTVNGANILVSPSAWVAGFMKKVHWEVMV 201

Query: 188 AARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQ 247
            ARA++   Y++A  + GN   G S  IDPFG T+        +   ++   ++   R  
Sbjct: 202 RARAIENGVYVLAPNQVGNIYCGHSMAIDPFGATVLDMKNRQGIEYVDIDTAKIDTTRRT 261

Query: 248 LPVLNNRR 255
           LP+L NRR
Sbjct: 262 LPLLMNRR 269


>UniRef50_D2R0U8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R0U8_9PLAN
          Length = 292

 Score =  133 bits (335), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 99/268 (36%), Positives = 144/268 (53%), Gaps = 18/268 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q   T     N     +L+ QAA   A L  LPE  ++  D     +V  AQ L G
Sbjct: 9   VAAIQMRATDDVAANFATAVTLVGQAAAAGARLVVLPELFVSYGDLARTAAV--AQSLLG 66

Query: 63  EFLGRLRRESK-RNMMTTILTI-HVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDA--- 116
            ++  L++ +K +N+     +I    +   RA+N    +   G IVA Y K+HL+D    
Sbjct: 67  TWITELQQLAKSKNIWLVAGSIPEQVANDQRAYNCSTVISPTGEIVAAYRKIHLFDVEIA 126

Query: 117 --FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              A QES  +  GNE+  +++++  +VG+  CYDLRFPEL    A  GAE++V+PAA+ 
Sbjct: 127 GRVASQESLHLLPGNELV-VVKIDDWQVGIAICYDLRFPELFRNLATLGAELVVIPAAFT 185

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA-SEM 228
           R   K+ HW  L+  RALD   Y+VAA + G+ N      G S I++P+G  IA   SE 
Sbjct: 186 RTTGKD-HWDLLVRTRALDAQAYIVAANQGGDHNGQSSSYGHSMIVEPWGKVIAQIDSED 244

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
             ++ + +  +RV +VR QLPVL NRR 
Sbjct: 245 EGIVFSSIDRKRVAEVRRQLPVLRNRRL 272


>UniRef50_B2J6W4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=11 Tax=Cyanobacteria RepID=B2J6W4_NOSP7
          Length = 270

 Score =  133 bits (334), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 90/268 (33%), Positives = 138/268 (51%), Gaps = 15/268 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L AA Q        KN      L+  A    A L  LPE      +    L+   A  LE
Sbjct: 5   LAAAIQLTSVPDLHKNLAQAEELIELAVRRGAELVGLPENFSYMGEEKDKLAQGDAIALE 64

Query: 62  GE-FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYD---- 115
            E FL ++ +  +  ++     + V +T G+ +N  + +  +G  ++RY K+HL+D    
Sbjct: 65  SEKFLKKMAQRFQITILGGSFPLPVDNT-GKVYNTTLLIDPSGQELSRYYKVHLFDVDVP 123

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGM-KVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                +ES  V AG ++ P+   E +  +GL  CYD+RFPEL    A +GA+++ +PAA+
Sbjct: 124 DGNTYRESSTVVAGTQLPPVHFSEKLGNLGLSICYDVRFPELYRHLAEKGADVIFIPAAF 183

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEM 228
                K+H W  LL ARA++ T Y++A  + GN        G + IIDP+GV +A A E 
Sbjct: 184 TAFTGKDH-WQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVIIDPWGVILADAGEK 242

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
           P + +AE+ P R+ QVR Q+P L +R F
Sbjct: 243 PGIAIAEIKPTRLEQVRRQMPSLQHRVF 270


>UniRef50_A1RZK0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RZK0_THEPD
          Length = 286

 Score =  133 bits (334), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 81/251 (32%), Positives = 128/251 (50%), Gaps = 9/251 (3%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA--DLSVKSAQLL 60
           VA  Q AV+    +N E    L+      DA L   PE L+  D      D   + A+ +
Sbjct: 18  VALHQLAVSGEKRENLEKALRLLELG---DAYLHVFPEYLMGVDPGGPTRDYVWRVAEPI 74

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +GEF  R+  ++    +  + T+ +   PG  +N  V  + G + A Y K+HL+DA+  +
Sbjct: 75  DGEFASRIVEKTGELGVAAVFTMFLREGPG-VYNAAVLAEEGKVKAVYRKIHLFDAYGYR 133

Query: 121 ESRRVDAGNEIAPLL-EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           ES     G E  P++ +++G+++G+  C+DLRFPEL  +  L+GAE+ V+P+AW RGP K
Sbjct: 134 ESSVFSPGRE--PVVADLKGLRLGIAVCFDLRFPELFRSMFLRGAEVFVVPSAWYRGPYK 191

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
              W  L AARA + T Y+VA  + G    G S +  P G  +    E    I  ++   
Sbjct: 192 VEQWKALTAARAHENTSYLVAVNQVGESFTGHSLVATPLGHLLVDLGEGERSIAVDLDEG 251

Query: 240 RVRQVRAQLPV 250
            +   R ++PV
Sbjct: 252 ELASARERIPV 262


>UniRef50_A0JSW0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Actinomycetales RepID=A0JSW0_ARTS2
          Length = 294

 Score =  132 bits (331), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 87/264 (32%), Positives = 129/264 (48%), Gaps = 17/264 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q        +N +I      +A +  A L   PEA + R   ++ L +  A+ L+G
Sbjct: 33  VALAQIVTGRDISRNLDIVEKYARKAKKGGAQLVVFPEATM-RAFGNSLLDI--AEPLDG 89

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQES 122
            +  R+R  ++   +  +  +  P    +  N L+    G + A Y K+HL+DAF   ES
Sbjct: 90  PWATRVRHIAREADIVIVAGMFTPGGGRKVRNTLLVTGPG-VEASYDKIHLFDAFGFAES 148

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
             VDAG   A   E+ G+K GL TCYD+RFP L  A A  GAE  ++ A+W  GP K   
Sbjct: 149 DTVDAGTR-ASTFELGGIKFGLATCYDIRFPALFTANADLGAEANIVCASWGSGPGKVDQ 207

Query: 183 WSTLLAARALDTTCYMVAAGE------------CGNKNIGQSRIIDPFGVTIAAASEMPA 230
           W  L  ARA+DTT Y++A G+                 +G S ++ P G  +        
Sbjct: 208 WRLLARARAVDTTTYVLACGQADPATEGIETKGSAPTGVGHSAVVSPLGEVLEELDAGTG 267

Query: 231 LIMAEVTPERVRQVRAQLPVLNNR 254
           L+ A++ P  V++ RA+LPVL NR
Sbjct: 268 LMFADLDPAVVKEARAKLPVLANR 291


>UniRef50_P55175 UPF0012 hydrolase sll0601 n=46 Tax=Cyanobacteria RepID=Y601_SYNY3
          Length = 272

 Score =  131 bits (330), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 90/269 (33%), Positives = 134/269 (49%), Gaps = 16/269 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQL 59
           L AA Q        +N +    L+  A    A L  LPE  A L  +    + +   A  
Sbjct: 5   LAAALQMTSRPNLTENLQEAEELIDLAVRQGAELVGLPENFAFLGNETEKLEQATAIATA 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
            E +FL  + +  +  ++       V    G+A+N    +   G  +ARY K+HL+D   
Sbjct: 65  TE-KFLQTMAQRFQVTILAGGFPFPVAGEAGKAYNTATLIAPNGQELARYHKVHLFDVNV 123

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGM-KVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  ES  V AG +  P+   +    +GL  CYD+RFPEL    + QGA++L +PAA
Sbjct: 124 PDGNTYWESATVMAGQKYPPVYHSDSFGNLGLSICYDVRFPELYRYLSRQGADVLFVPAA 183

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASE 227
           +     K+H W  LL ARA++ TCY++A  + G         G + IIDP+GV +A A E
Sbjct: 184 FTAYTGKDH-WQVLLQARAIENTCYVIAPAQTGCHYERRHTHGHAMIIDPWGVILADAGE 242

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            P L +AE+ P+R++QVR Q+P L +R F
Sbjct: 243 KPGLAIAEINPDRLKQVRQQMPSLQHRVF 271


>UniRef50_Q9HIW8 Nitrilase related protein n=2 Tax=Thermoplasma RepID=Q9HIW8_THEAC
          Length = 270

 Score =  131 bits (329), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 76/257 (29%), Positives = 131/257 (50%), Gaps = 4/257 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKS-AQL 59
           M VA  Q   ++  EKN E    L+ +A  +D  +F  PE  +     D    +K+ ++ 
Sbjct: 1   MKVAVVQMESSTDREKNIEASYRLLEKAKNSDLVVF--PEYQIYAPAFDGKDDMKTISEP 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVALQAGNIVARYAKLHLYDAFA 118
           L+G+F+  +   ++      IL I   +    + +N  + +    ++ +Y KLHL+DAF 
Sbjct: 59  LDGKFVKSITEIARSESQKIILNIPERNQYNLKPFNTAIYIDELGLILKYRKLHLFDAFG 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +ES   + G+    +    G  +G++ CYDLRFPE A   AL GA++++  A W  G  
Sbjct: 119 FRESSVFEKGDARPAIFNGSGDPLGVLICYDLRFPEPARMLALDGAKLIIYQAGWFAGER 178

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K   W TLL ARA++   +++ A + G++  G S +I P+G  +A       +I  ++  
Sbjct: 179 KYDQWKTLLKARAMENGVFVIGAAQTGHRFTGHSMVISPYGDVLAEMGTDEGVITFDIDF 238

Query: 239 ERVRQVRAQLPVLNNRR 255
             V + R ++PVL +RR
Sbjct: 239 SLVEKYREEVPVLKHRR 255


>UniRef50_A2Q9D7 Catalytic activity: nitrilases catalyze a nitrile + H(2)O <=> a
           carboxylate + NH(3) n=2 Tax=Dikarya RepID=A2Q9D7_ASPNC
          Length = 274

 Score =  130 bits (326), Expect = 5e-29,   Method: Compositional matrix adjust.
 Identities = 89/272 (32%), Positives = 142/272 (52%), Gaps = 15/272 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +L A GQ   T+    N   C +L+ +AA   A    LPEA        A+    +  + 
Sbjct: 2   VLTAVGQLCSTASLAANLAQCQTLVRKAAAAGAKALFLPEASDYIASSPAETISLARSVQ 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD---- 115
           + EF+  L++E++   +   + IH P+  GR  N L+ + + GNI  RY K+HL+D    
Sbjct: 62  DSEFVLGLQKEAQLANLHINVGIHEPAANGRIKNTLIWINEQGNITQRYQKVHLFDVDIK 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               ++ES  V+ G EI P  E    +VGL  C+DLRFPE++LA   Q A+I+  P+A+ 
Sbjct: 122 GGPVLKESASVEKGMEILPPFETPVGRVGLSICFDLRFPEISLALRRQNAQIITYPSAFT 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS--- 226
             P    HW TLL ARA++T  Y++AA + G  N      G S I++P+G  +A      
Sbjct: 182 V-PTGTAHWETLLRARAIETQSYVIAAAQAGPHNEKRRSYGHSMIVNPWGEVVAKLGDEY 240

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
           + P + +A++  + + +VR ++P+L      P
Sbjct: 241 QEPQIAVADIDLDLLAKVRREMPLLRRTDIYP 272


>UniRef50_Q6L0F7 Carbon-nitrogen hydrolase family n=1 Tax=Picrophilus torridus
           RepID=Q6L0F7_PICTO
          Length = 256

 Score =  129 bits (325), Expect = 7e-29,   Method: Compositional matrix adjust.
 Identities = 73/244 (29%), Positives = 124/244 (50%), Gaps = 6/244 (2%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           E N E        AA N A L   PE  +   +    L+ ++A+ + G ++  + +    
Sbjct: 16  ESNLEKLRKYTEIAASNGADLIVFPEYFMFYSNDKKYLN-ENAEPINGIWVKNVIKIFNE 74

Query: 75  NMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPL 134
           N ++ I+ I+        ++  V + +G++   Y K  LYDAF  +ES    +GN    L
Sbjct: 75  NSISGIVCIN-ELNDNNVFDTAVYI-SGDVKGYYRKKMLYDAFGYRESDIYKSGNGPFNL 132

Query: 135 LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDT 194
             +  +  G++ CY++RFPEL    +  GA+++++P+ W  GP+KE  W +LL ARAL+ 
Sbjct: 133 YRINDISFGILICYEIRFPELFRNYSKNGADMIIIPSGWFSGPVKEEQWLSLLRARALEN 192

Query: 195 TCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPV---L 251
           T Y+ ++ +      G S + DP G+    A E   +I  +V  ER+  VR ++P+   L
Sbjct: 193 TVYIASSNQIYGDFTGISAVADPIGIISERAGESETMIFYDVKKERINDVRQKMPLLEQL 252

Query: 252 NNRR 255
           NN R
Sbjct: 253 NNLR 256


>UniRef50_D2A1E5 Putative uncharacterized protein GLEAN_07103 n=3 Tax=Coelomata
           RepID=D2A1E5_TRICA
          Length = 445

 Score =  129 bits (325), Expect = 7e-29,   Method: Compositional matrix adjust.
 Identities = 90/277 (32%), Positives = 142/277 (51%), Gaps = 30/277 (10%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEA--LLARDDHDADLSVKSAQLL 60
           VA  QF  T+  E N +I   L+++AA+  A +  LPEA   +A + ++A      A+ L
Sbjct: 8   VAVCQFTATNNKENNLQIVKQLVSEAAQKQAKIVFLPEASDYIAANKNEAK---AFAEPL 64

Query: 61  EGEFLGRLRRESK-RNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDA-- 116
            G  +   R  +K R +  ++   H      + +N  V +   G I + Y KLHL+D   
Sbjct: 65  NGTLMNEYRNLAKTRKVWLSVGGFHELVNEHQIFNTHVLIDDEGEIKSVYKKLHLFDVSI 124

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                 ++ES   +AG  + P +      + L  CYDLRFPEL++ Q  QGA IL  P+A
Sbjct: 125 PELNVNLRESDLNEAGRHLVPPVMTPAGPLALAICYDLRFPELSIIQRKQGANILTYPSA 184

Query: 173 WVR--GPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA 225
           + +  G L   HW TLL +RA++T CY++AA + G  N      GQ+ I+DP G  IA  
Sbjct: 185 FTKATGAL---HWETLLRSRAIETQCYVIAAAQYGKHNEKRTSYGQALIVDPQGKIIAEC 241

Query: 226 SEM-------PALIMAEVTPERVRQVRAQLPVLNNRR 255
            +         ++ +AE+    +++VR ++PV  +RR
Sbjct: 242 PKYREGHETNQSIAIAEIDSNLIQKVRTEMPVFQHRR 278


>UniRef50_A0PVY5 Amidohydrolase n=12 Tax=Actinomycetales RepID=A0PVY5_MYCUA
          Length = 280

 Score =  129 bits (324), Expect = 9e-29,   Method: Compositional matrix adjust.
 Identities = 90/277 (32%), Positives = 135/277 (48%), Gaps = 28/277 (10%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVK---SA 57
           M +A  Q    +    N E+      +AA+  A L   PEA + R        V     A
Sbjct: 1   MRIALAQILSGTDPTANLELVRDYAERAADAGARLVVFPEATMCR------FGVPLGPVA 54

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG---NIVARYAKLHLY 114
           Q L+G +   +RR + +  +T +  +  P+  GR  N L A   G        Y K+HLY
Sbjct: 55  QPLDGPWANGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKIHLY 114

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           DAF   ESR V  G+E   ++ V+  +VGL  CYD+RFP L    A +GAE++V+ A+W 
Sbjct: 115 DAFGFAESRTVAPGHEPV-VITVDDFQVGLTVCYDIRFPALYTELARRGAELIVVSASWG 173

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGEC--GN------------KNIGQSRIIDPFGV 220
            GP K   W+ L  ARALD+  Y+ AAG+   G+            + +G S +  P G 
Sbjct: 174 SGPGKLDQWTLLARARALDSASYVAAAGQADPGDTASDPGGGSGAPRGVGGSLVTSPLGE 233

Query: 221 TIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR-RF 256
            +A+A   P L++A++   +V   R  + +L N+ RF
Sbjct: 234 VVASAGSDPQLVVADIDLAKVGAARDNIGMLRNQSRF 270


>UniRef50_Q6C005 YALI0F29139p n=1 Tax=Yarrowia lipolytica RepID=Q6C005_YARLI
          Length = 289

 Score =  129 bits (324), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 99/289 (34%), Positives = 152/289 (52%), Gaps = 48/289 (16%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEAL------------LARDDHD 49
           L A GQF  T+    NA I A L+ +AA   A    LPEA             LAR+  +
Sbjct: 3   LAAVGQFCATNSLTHNASIVAGLVHRAAALGAQALFLPEASDYISGSPKEGLSLARNAEN 62

Query: 50  ADL--SVKSAQLLEGEFLGRLRRESKRNMMTTI---LTIH-VPSTPGRAWNMLVALQA-G 102
           + +  +++ AQ           +E K++ M+ I   + +H + S+  R  N L+ L + G
Sbjct: 63  SPMIAAIREAQ-----------KEIKQSGMSGIEVSVGVHELSSSSDRVRNTLLWLDSNG 111

Query: 103 NIVARYAKLHLYDAFA-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELAL 157
           +IV RY K+HL+D        +QES+ V+ G+E+    E     VG   CYD+RFPELAL
Sbjct: 112 DIVNRYQKVHLFDVEVPNGPILQESKSVEPGSELPKPFETPVGTVGPAICYDIRFPELAL 171

Query: 158 AQALQGAEILVLPAAW-VRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-------KNI 209
               QGA+IL  P+A+ VR      HW  L  ARA+DT CY++     G        ++ 
Sbjct: 172 LLRKQGAQILQFPSAFTVR--TGAAHWHVLARARAIDTQCYVMMPALVGKHTEDGKRESY 229

Query: 210 GQSRIIDPFGVTIAAASEMP---ALIMAEVTPERVRQVRAQLPVLNNRR 255
           G + IIDP+G  +A AS++    A+I+A++  E++++VR  +P+ + RR
Sbjct: 230 GHAMIIDPWGTVLAEASDIDSSAAVIVADINLEQLKKVRTNMPLWDQRR 278


>UniRef50_B9ZGS1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Natrialba magadii ATCC 43099 RepID=B9ZGS1_NATMA
          Length = 271

 Score =  126 bits (317), Expect = 7e-28,   Method: Compositional matrix adjust.
 Identities = 91/270 (33%), Positives = 139/270 (51%), Gaps = 25/270 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +AA Q       E N       + +AA+  A + +LPE      + +A      A+ + G
Sbjct: 6   IAACQMDSQDDKEANLTQALDFIDEAAQKGADVVSLPEMFSFMGEKEA--YSTHAEPVPG 63

Query: 63  EFLGRLRRESKRNMMTTILTIHVPS------TPGRAWNMLVALQ-AGNIVARYAKLHLYD 115
           E    L  ++     T  L +H  S         R +N  V +   G I A+Y K HL+D
Sbjct: 64  ETTAALADKA----TTHGLHVHSGSFFEKAGDGDRVYNTSVVIDPDGEIQAQYRKTHLFD 119

Query: 116 A-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                    QES+ V  G+++  ++E +    GL  CYDLRF EL  + A+QGAE+L +P
Sbjct: 120 VTIGDEVVTQESKHVAPGDDVT-VVETDLATFGLSVCYDLRFSELYRSMAMQGAEVLFVP 178

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAA 225
           AA+     K+ HW  LL ARA++T CY+VAAG+ G+K     + G+S IIDP+G  I  A
Sbjct: 179 AAFTLFTGKD-HWLPLLKARAIETQCYVVAAGQIGDKPSSVPSFGKSVIIDPWGNVIRMA 237

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           S+   ++ AEV  + + +VR ++P L ++R
Sbjct: 238 SDREEVVTAEVDLDYLAEVRQKIPCLEHKR 267


>UniRef50_D1Y828 Hydrolase n=1 Tax=Pyramidobacter piscolens W5455 RepID=D1Y828_9BACT
          Length = 275

 Score =  125 bits (315), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 66/163 (40%), Positives = 98/163 (60%), Gaps = 11/163 (6%)

Query: 102 GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G++ ARY K+H+YD       + +ES     G+ I  + + E  KVGL  CYD+RFPE+ 
Sbjct: 106 GDLAARYEKIHMYDVEIENGPSTRESDTKKPGHRIV-VADTEFCKVGLSICYDMRFPEMY 164

Query: 157 LAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQS 212
              ALQGA+++ +PA +     K+H W  +L  RA++  CY+VA  + G K      G+S
Sbjct: 165 RIMALQGAKVMFVPANYTLFTGKDH-WECILKTRAIENQCYVVAPAQIGKKPAFQAYGRS 223

Query: 213 RIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            II+P+GVT+A A +   +I AE+ P+ V Q+R QLP L NR+
Sbjct: 224 MIINPWGVTVACAEDRETIIYAEIDPDYVNQIREQLPSLKNRQ 266


>UniRef50_Q5A428 Nitrilase superfamily protein n=4 Tax=Candida RepID=Q5A428_CANAL
          Length = 299

 Score =  125 bits (315), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 88/291 (30%), Positives = 143/291 (49%), Gaps = 43/291 (14%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEA--LLARDDHDADLSVKSAQLL 60
           +A GQ   +S   +N  +   L+ +A    A L  LPEA   ++R+   A+ S++ +Q +
Sbjct: 6   IAVGQLCSSSNLSQNLRVVKKLLQKAQLEKARLLFLPEATDYISRN---ANHSIELSQEV 62

Query: 61  EGEFLGRLRRESKRNMMTTILTI--HVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
           +  FL  L    K    +T L+I  H+P    R  N+ V +   G IV+ Y K+HL+D  
Sbjct: 63  QSNFLSPLLDYVKSLNGSTYLSIGIHLPGKK-RVRNVHVLIDPKGAIVSEYQKVHLFDVD 121

Query: 118 A-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                 ++ES  V+ GN+I   + ++  K+GL  CYD+RFPELAL     G++I+  P+A
Sbjct: 122 VPNGPILKESNSVEPGNKIEDPIPIDDFKLGLGICYDIRFPELALRLRRLGSDIITFPSA 181

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----------------GQSRIID 216
           +      E HW  L  ARA+D+ C+++ A +CG   +                G S I+D
Sbjct: 182 FTTR-TGEAHWELLSKARAIDSQCFVINAAQCGQHQVGTDPNDLSKVIKRISYGDSIIVD 240

Query: 217 PFGVTIAAASEMP------------ALIMAEVTPERVRQVRAQLPVLNNRR 255
           P+G  +A   +               LI AE+  +    +R  +P+L++RR
Sbjct: 241 PWGEVLARGEKYTDELKHDDDGDYYELIQAELKLDDSESIRKNMPLLDHRR 291


>UniRef50_B0MEV6 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0MEV6_9FIRM
          Length = 272

 Score =  124 bits (312), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 79/246 (32%), Positives = 120/246 (48%), Gaps = 5/246 (2%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           EKN         +A E  A     PE  +     +     + AQ L+G F+  ++R +  
Sbjct: 17  EKNLCKAEFFCREAREESACFVIFPEYFMTYYPIEGSAYYEKAQTLDGPFVQGMKRLAAA 76

Query: 75  NMMTTILTIHVP---STPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNE 130
           +    +  +       + G+ +N  V L   GN+ + Y K HL+DAF+ +ES     G  
Sbjct: 77  HGQWILFGMSEKPGRDSGGKCFNTAVLLDDRGNLCSVYRKTHLFDAFSWKESDSTLPGEV 136

Query: 131 IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAAR 190
           +   +     K GL TCYDLRFPE A  QAL+GAE+L+ P+AWV GP K   W  LL AR
Sbjct: 137 LHEPVNTPLGKAGLGTCYDLRFPEPARIQALKGAEVLIYPSAWVDGPDKFMQWEALLRAR 196

Query: 191 ALDTTCYMVAAGECGNKN-IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLP 249
           A++ T + +       ++ +G+S   DP G  +A       LI+  V  ++   +  Q+P
Sbjct: 197 AIENTVFTIGCCHYSEEHYMGRSLAFDPSGRKLAEGEAGEELIVLPVDTDQRDAIIHQVP 256

Query: 250 VLNNRR 255
           V+ NRR
Sbjct: 257 VMKNRR 262


>UniRef50_UPI000051A529 PREDICTED: similar to Nitrilase and fragile histidine triad fusion
           protein CG7067-PA n=2 Tax=Coelomata RepID=UPI000051A529
          Length = 304

 Score =  124 bits (312), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 90/269 (33%), Positives = 132/269 (49%), Gaps = 17/269 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           LVA  Q   T+  EKN +    L  +A    AS+   PEA     D   D ++  AQ L 
Sbjct: 28  LVAVCQMTSTNDKEKNLQTVRELSEKAKHRAASIAFFPEACDYLADSKKD-TIAMAQTLN 86

Query: 62  GEFLGRLRRESKRNMM-TTILTIHVPSTPGRAW--NMLVALQA-GNIVARYAKLHLYD-- 115
           G  +   +  +K N +  ++  IH      R    N  + + + G IV+ Y K+HL+D  
Sbjct: 87  GSTVTSYKEIAKINKIWLSLGGIHEALDNNREHISNTHILINSEGEIVSTYRKIHLFDMD 146

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                  + ES  V  G +I P +     K+ L  CYD+RFPEL+ +    GAEIL  P+
Sbjct: 147 NKNTGVRLMESDYVLPGQKIEPPISTPIGKLALSICYDMRFPELSFSLRNMGAEILTYPS 206

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAAS 226
           A+        HW  LL ARA++T CY+VAA +    N      G + +IDP+G  IA  S
Sbjct: 207 AFTYQT-GAAHWEILLRARAIETQCYVVAAAQTSIHNKKRVSWGHAMVIDPWGSIIAQCS 265

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           E   +I+AE+    ++Q+R  +P  N+RR
Sbjct: 266 EKTDIILAEIDLNLLKQIRQNMPCENHRR 294


>UniRef50_D1Y612 Hydrolase n=2 Tax=Bacteria RepID=D1Y612_9BACT
          Length = 274

 Score =  124 bits (310), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 90/272 (33%), Positives = 134/272 (49%), Gaps = 29/272 (10%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL- 60
           L+A  Q       + N +     + +AA   A   + PE     D+       ++ +L+ 
Sbjct: 5   LMAVIQMDTRDNKDANLKAACDFIDEAASKGAKFVSFPEVFNVIDE-----GQEAPELVP 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP------GRAWNMLVALQ-AGNIVARYAKLHL 113
           EG  +  +  +++R+     L IH  S         R +N    L   G +VA+Y KLH 
Sbjct: 60  EGRTISLMAEKARRHN----LWIHCGSIAEVNPEGDRKFNTTAVLNPQGRMVAKYRKLHT 115

Query: 114 YD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
           +D         +ES R+  G E+    + E   +GL  CYD+RFPEL    AL GA+IL 
Sbjct: 116 FDITLPDGSVAEESARIKPGREMV-TADTEMGCLGLSICYDIRFPELYRYLALHGAQILF 174

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIA 223
            PA + R    + HW  +L ARA++ TCY+VAAG+ G K+      G S IIDP+G  +A
Sbjct: 175 APANF-RMATGKDHWEAILRARAIENTCYVVAAGQYGKKHGTSDSFGNSMIIDPWGTVVA 233

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            ASE   L + E+  + + +VR+ LP L NRR
Sbjct: 234 RASEGAGLAVGEIDLDYLDKVRSHLPSLKNRR 265


>UniRef50_O76463 Nitrilase homolog n=6 Tax=Bilateria RepID=NFT1_CAEEL
          Length = 440

 Score =  122 bits (306), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 81/272 (29%), Positives = 132/272 (48%), Gaps = 24/272 (8%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEAL----LARDDHDADLSVKSA 57
            +A  Q    +  EKN +   +++ +A E    +  LPE      L +++      +  A
Sbjct: 16  FIAVCQMTSDNDLEKNFQAAKNMIERAGEKKCEMVFLPECFDFIGLNKNE-----QIDLA 70

Query: 58  QLLEGEFLGRLRR-ESKRNMMTTILTIHV--PSTPGRAWNMLVALQAGNIV-ARYAKLHL 113
              + E++ + R    K N+  ++  +H   PS     WN  + + +  +  A Y KLHL
Sbjct: 71  MATDCEYMEKYRELARKHNIWLSLGGLHHKDPSDAAHPWNTHLIIDSDGVTRAEYNKLHL 130

Query: 114 YD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
           +D        + ES    AG E+ P ++    ++GL  CYD+RFPEL+L    +GA++L 
Sbjct: 131 FDLEIPGKVRLMESEFSKAGTEMIPPVDTPIGRLGLSICYDVRFPELSLWNRKRGAQLLS 190

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIA 223
            P+A+        HW TLL ARA++  CY+VAA + G  N      G S ++DP+G  +A
Sbjct: 191 FPSAFTLNTGLA-HWETLLRARAIENQCYVVAAAQTGAHNPKRQSYGHSMVVDPWGAVVA 249

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
             SE   +  AE+    V  +R   PV ++RR
Sbjct: 250 QCSERVDMCFAEIDLSYVDTLREMQPVFSHRR 281


>UniRef50_B9L3Z7 Hydrolase, carbon-nitrogen family protein n=8 Tax=Bacteria
           RepID=B9L3Z7_THERP
          Length = 279

 Score =  122 bits (305), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 91/254 (35%), Positives = 128/254 (50%), Gaps = 19/254 (7%)

Query: 16  KNAEICASLMAQAAENDASLFALPEA---LLARDDHDADLSVKSAQLLEGEFLGRLRRES 72
           +N  +   L+ +AA   A L ALPE    L  R+ H+A+         E  F    RR  
Sbjct: 20  ENLAVAERLIEEAARQGAELVALPEYVNFLGPRELHEANAEPIPGPTTE-RFAALARRYG 78

Query: 73  KRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA-----FAIQESRRVD 126
              +  +IL     + PG+ +N  V     G I+A Y K+HL+D          ES  + 
Sbjct: 79  IYLLGGSIL--ERSAIPGKYYNTSVLFAPDGEIIASYRKIHLFDVDLTGNVTSNESATIL 136

Query: 127 AGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTL 186
            G+ +    EV G  VGL  CYDLRFPEL    AL GAE++++PAA+     K+ HW TL
Sbjct: 137 PGDRVV-TAEVAGHVVGLTICYDLRFPELYRLLALDGAELILVPAAFTLYTGKD-HWHTL 194

Query: 187 LAARALDTTCYMVAAGECGNKNIGQ-----SRIIDPFGVTIAAASEMPALIMAEVTPERV 241
           L ARA++  CY+ A  + G  + GQ     S + DP+G  IA A     +++  +    +
Sbjct: 195 LRARAIENQCYVAAPAQIGPHDPGQQCYGHSLVADPWGTVIAEAINRVGVVVTTLDFAYL 254

Query: 242 RQVRAQLPVLNNRR 255
           R+VRAQLP L NRR
Sbjct: 255 REVRAQLPSLANRR 268


>UniRef50_A2BKF1 Predicted amidohydrolase n=1 Tax=Hyperthermus butylicus DSM 5456
           RepID=A2BKF1_HYPBU
          Length = 272

 Score =  122 bits (305), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 63/162 (38%), Positives = 96/162 (59%), Gaps = 1/162 (0%)

Query: 92  AWNMLVALQAGNIV-ARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDL 150
           A++ +V ++ G  V   Y K  L+DA  ++ES+ +  G +  P+LEV G++VG + C++L
Sbjct: 95  AYSSIVMVEPGKEVQVVYRKTVLFDALGVRESKSLCRGEQPPPVLEVRGVRVGFIVCFEL 154

Query: 151 RFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIG 210
           RFPELA + AL+GAE++ +PAAW RG LKE H      +RAL+ T Y+  A   G    G
Sbjct: 155 RFPELARSLALRGAELVAVPAAWYRGNLKEEHLLVTARSRALENTVYLAVASMTGPHFTG 214

Query: 211 QSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLN 252
           +S ++DP GV        P     +V  + + +VR QLP+L 
Sbjct: 215 RSILVDPMGVVRLDLGSEPGYAEVDVDLDYINEVRKQLPLLE 256


>UniRef50_UPI000185C288 hydrolase n=1 Tax=Corynebacterium amycolatum SK46
           RepID=UPI000185C288
          Length = 280

 Score =  121 bits (304), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 89/282 (31%), Positives = 144/282 (51%), Gaps = 31/282 (10%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALL-ARDDHDADLSVKSAQL 59
           M +A  Q  +++  E+N +   + +A+AA+ +A L   PEA + A +    D+  +S+  
Sbjct: 1   MRIALAQLELSASVEENLDAVKATIARAAQGNADLVVFPEATMKAFNSGRLDVVAESSS- 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPS--------TPGRAWNMLVAL---QAGNIVARY 108
               F+  + + +    ++ ++ +  P+        T  R +N L+     + G  V  Y
Sbjct: 60  --DRFVAEVSQAAHDAGISVVVGMFRPADQVERDGKTMHRVFNSLLLAWRDEDGPGVEFY 117

Query: 109 AKLHLYDAFAIQESRRVDAGNE----IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA 164
            KLHL+DAF  +ES  V  GN       PL +   + +GL TC+D+RFPE  +  A  GA
Sbjct: 118 DKLHLFDAFGFRESDTVAPGNAHVVCDVPLADGSSVALGLATCFDIRFPEQFIQLANLGA 177

Query: 165 EILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMV-----------AAG-ECGNKNIGQS 212
           E++ LPA+W  GP K   W TL++ARALD+TC +            AAG + G    G S
Sbjct: 178 EVIALPASWNDGPGKVLQWQTLVSARALDSTCVIAAVDAARPGGAKAAGKDEGPTGAGYS 237

Query: 213 RIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
            +++  G  IA+A   P L++A+V    V ++R  +PVL  R
Sbjct: 238 MLVNADGGVIASAGYGPQLLVADVDIAEVERIRRSIPVLEIR 279


>UniRef50_P47016 Probable hydrolase NIT2 n=9 Tax=Saccharomycetaceae RepID=NIT2_YEAST
          Length = 307

 Score =  121 bits (304), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 90/297 (30%), Positives = 146/297 (49%), Gaps = 46/297 (15%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEA--LLARDD-HDADLSVKSAQL 59
           VA  Q   ++   KN ++   L+++A +  A +  LPEA   L+++  H   L+ KS + 
Sbjct: 8   VAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKF 67

Query: 60  LEG--EFLGRLRRESKRNMMTTILTIHVPSTP-------GRAWNMLVAL-QAGNIVARYA 109
           +      +  L R++ RN+  +I  +H+P +         R  N+L+ +   G I+  Y 
Sbjct: 68  IRQLQSSITDLVRDNSRNIDVSI-GVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQ 126

Query: 110 KLHLYDAFA-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA 164
           KLHL+D        ++ES+ V  G  I  ++E    K+G   CYD+RFPE +L     GA
Sbjct: 127 KLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGA 186

Query: 165 EILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI--------------- 209
           EIL  P+A+      E HW  L  ARA+DT CY++  G+ G  ++               
Sbjct: 187 EILCFPSAFTIK-TGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALE 245

Query: 210 --------GQSRIIDPFGVTIAAASEM---PALIMAEVTPERVRQVRAQLPVLNNRR 255
                   G S +IDP+G  IA A      P LI+A++  E ++++R ++P+ N RR
Sbjct: 246 KSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRR 302


>UniRef50_C7NXL9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Halobacteriaceae RepID=C7NXL9_HALMD
          Length = 270

 Score =  121 bits (303), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 83/259 (32%), Positives = 128/259 (49%), Gaps = 24/259 (9%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           E N E   +++ +AA+    L ALPE L A      D   ++A+ L G  L RLR  +  
Sbjct: 16  EANVERATAMIERAADRGVGLVALPE-LFATGYFAFDAYARTAESLTGPTLTRLRETAAE 74

Query: 75  NMMTTILT-------------IHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQE 121
             +  +               I  P+T G A   ++    G   + Y K HL+  +   E
Sbjct: 75  QDLALLAGSIVEDLAASHAAGIETPATEGYANTSVLFDSDGRRRSVYRKHHLF-GYGSAE 133

Query: 122 SRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL-KE 180
              ++ G  I    ++ G  VG+ TCYDLRFPEL    A +G  ++++P+AW   P  + 
Sbjct: 134 QDLLEPGERIQ-TADIGGFTVGVTTCYDLRFPELYRELADRGVTLVLVPSAW---PYPRV 189

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEV 236
            HWS L  ARA++   Y+ AA   G  +    +G+S + DP+G  IA+  + PAL+ A++
Sbjct: 190 EHWSVLPKARAVENLTYVAAANGVGTFDGEALLGRSTVYDPWGTPIASTGDEPALVTADL 249

Query: 237 TPERVRQVRAQLPVLNNRR 255
            P+RV  VR   P L++RR
Sbjct: 250 DPDRVAAVRESFPALDDRR 268


>UniRef50_C6CYG4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Bacillales RepID=C6CYG4_PAESJ
          Length = 270

 Score =  120 bits (302), Expect = 3e-26,   Method: Compositional matrix adjust.
 Identities = 65/168 (38%), Positives = 98/168 (58%), Gaps = 10/168 (5%)

Query: 93  WNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLR 151
           +N + A  + GN +  Y+K+HL+    + E + + AG+++  L E+EG   G+M CYD+R
Sbjct: 104 YNTIYAFDREGNQIGDYSKIHLFRL--MDEEKYLAAGDKLGKL-EIEGAGAGMMICYDIR 160

Query: 152 FPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG----NK 207
           FPELA   AL GA++L +PA W    L  HHW TLL ARA++   +++A    G      
Sbjct: 161 FPELARKLALDGAKLLFVPAEWPHPRL--HHWRTLLTARAIENQMFVIACNRVGISGDTH 218

Query: 208 NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
             G S ++DP+G TIA A E   ++ AE+    V  VR ++PV  +RR
Sbjct: 219 FFGHSMVLDPWGETIAEAGEEETILYAEIDLSLVDTVRGKIPVFEDRR 266


>UniRef50_C9D316 Hydrolase n=1 Tax=Silicibacter sp. TrichCH4B RepID=C9D316_9RHOB
          Length = 276

 Score =  120 bits (300), Expect = 6e-26,   Method: Compositional matrix adjust.
 Identities = 76/177 (42%), Positives = 99/177 (55%), Gaps = 15/177 (8%)

Query: 91  RAWNMLVALQ-AGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGL 144
           R WN    +   G I ARY KLH +D     A    ESR V  G   A   E +G+K+GL
Sbjct: 94  RIWNRGHMISPTGAITARYDKLHTFDVALGGAGDFIESRAVAPGQRGAITCEADGLKLGL 153

Query: 145 MTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAG 202
             CYDLRF  L  A A  GA +L++PA++  + GPL   HW  LL ARA++T  Y+VAA 
Sbjct: 154 SICYDLRFSYLFRALASAGASVLMIPASFSPITGPL---HWEPLLKARAIETGSYVVAAA 210

Query: 203 ECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           + G ++     GQSRII P G  +AAA + P +I AE+    V + R +LPVL   R
Sbjct: 211 QSGTRDGLRTHGQSRIISPMGEVLAAAGDEPGVICAEIDLAEVTETRRRLPVLAQTR 267


>UniRef50_Q11M91 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Chelativorans sp. BNC1 RepID=Q11M91_MESSB
          Length = 272

 Score =  119 bits (299), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 86/249 (34%), Positives = 128/249 (51%), Gaps = 19/249 (7%)

Query: 23  SLMAQAAENDASLFAL-PEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTIL 81
           SL+  A E D S + L PE       + A +   +  L +GE L R+   + R + TTI 
Sbjct: 24  SLVRAAHEADHSDYILTPEHSFCLTANKATMHAAAETLEDGEGLRRMASLA-RELGTTIH 82

Query: 82  TIHVPST-PGRAWNMLVALQ-AGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPL 134
              + +T  GR +N  V +   G  +A Y K+H YD       + +ES   DAGN +A  
Sbjct: 83  IGSILTTRNGRYYNTSVVIGPDGKQLATYDKIHRYDVDLPSGLSYRESDTNDAGN-VAVT 141

Query: 135 LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDT 194
            +  G  VGL  CYD+RF  L L  A +GA+++ +PAA+        HW TL+ ARA++T
Sbjct: 142 YDHNGTNVGLSVCYDVRFGSLYLELAARGAQVITIPAAFTF-ETGAAHWDTLVRARAIET 200

Query: 195 TCYMVAAGECGN--------KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRA 246
            CY+ AAG+ G+         + G S+I+DP+G  +A  S++     A + P    +VR 
Sbjct: 201 QCYVAAAGQVGSFPASGGDRASFGNSQIVDPWGKVLARCSDVEGWASAAIDPSYQNRVRQ 260

Query: 247 QLPVLNNRR 255
            LPV  +RR
Sbjct: 261 NLPVARHRR 269


>UniRef50_C1TRG7 Predicted amidohydrolase n=1 Tax=Dethiosulfovibrio peptidovorans
           DSM 11002 RepID=C1TRG7_9BACT
          Length = 274

 Score =  119 bits (299), Expect = 7e-26,   Method: Compositional matrix adjust.
 Identities = 85/265 (32%), Positives = 134/265 (50%), Gaps = 15/265 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEA--LLARDDHDADLSVKSAQLL 60
           VAA Q       E N     +++ +A +  ASL   PE   LL     + +   +     
Sbjct: 6   VAAAQMDSGPEKEINLIHMETMIEEAGKRGASLVVFPETSTLLPSSGIEKEAGAEPVPGP 65

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD---- 115
             + L +  RE+   + +  L   +     + +N  V +   G + A+Y K+HL+D    
Sbjct: 66  STDRLSKAAREAGIWVHSGSLLERIEGNE-KCYNTSVLISPEGEVTAKYRKIHLFDVNVH 124

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              +++ES    +GNEI  + E     +G+  CYDLRFPEL    AL+GA++LV+PA + 
Sbjct: 125 DGPSVRESASYASGNEIV-IAETPLGNIGMSICYDLRFPELYRILALRGAQVLVVPACFT 183

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPA 230
               KE HW  LL ARA++  CY+VA G+ G+K      G+S ++DP+G   A  +    
Sbjct: 184 SDTGKE-HWDPLLRARAIENLCYVVAPGQVGSKPRYRAHGKSMVVDPWGTVTACRASGEG 242

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRR 255
           L++AEV  +R+  +R  +P L NRR
Sbjct: 243 LVLAEVDLDRLESLRHSVPCLQNRR 267


>UniRef50_A6VWN8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Marinomonas RepID=A6VWN8_MARMS
          Length = 277

 Score =  119 bits (299), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 83/277 (29%), Positives = 132/277 (47%), Gaps = 25/277 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q   T  W+ N      L+A AA + A L  LPE +     H   +   +    
Sbjct: 4   LCVAAIQLTSTISWQDNLREVKHLVASAARDGARLVVLPENVFLF--HGKGMRCLAESDD 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA----------GNIVARYAK 110
           +      +   ++ + +  ++  H PS    + +++V  +           G +  RY K
Sbjct: 62  QSVIFKEISALAQEHSIYLVVGSH-PSLLRPSGDLVVDERVRQTCWVIGPDGLLYERYDK 120

Query: 111 LHLYD------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA 164
           +HL+D      A + +ES  ++ G     +++V+G KVGL  CYDLRFPEL       GA
Sbjct: 121 IHLFDVTVDDKATSYKESGVIEPGELALKVIDVDGFKVGLSICYDLRFPELYRELTKLGA 180

Query: 165 EILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFG 219
           E+L++PAA+     K  HW  LLAARA++  CY++  G+CG  N      G S +  PFG
Sbjct: 181 EVLLVPAAFTYVTGKA-HWDILLAARAIENQCYVLGVGQCGWHNETRQTYGHSVLYSPFG 239

Query: 220 VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             +A   E P   +  +T   +   R ++P L++RR 
Sbjct: 240 ERLANLEEEPGYFVFNMTKTALSNCRQKMPCLSHRRL 276


>UniRef50_B6HUF1 Pc22g05380 protein n=28 Tax=Leotiomyceta RepID=B6HUF1_PENCW
          Length = 274

 Score =  119 bits (298), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 85/276 (30%), Positives = 137/276 (49%), Gaps = 23/276 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +L A GQ   TS    N   C  L+ +AA   A +  LPEA     D+ A  + +S  L 
Sbjct: 2   VLAAVGQLCSTSNITSNLAQCKVLVRKAAAAGAKVLFLPEA----SDYIASSAEQSYSLA 57

Query: 61  EGE----FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYD 115
             E    F+  L+R++    +   + IH  ++  R  N+L+ +   G I  +Y K+H++D
Sbjct: 58  GSEERTSFVSSLQRDALEQNIHINVGIHEVASETRLKNLLIWIDDKGIITQKYQKIHMFD 117

Query: 116 AF-----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                   ++ES  V  G +I    E    +VGL  C+DLRFPE+ LA   + AEI+  P
Sbjct: 118 VDIKDGPVLKESASVQPGQQIPTPFETPIGRVGLSICFDLRFPEIGLALRRKDAEIITYP 177

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAA- 224
           +A+   P  + HW  LL ARA++T  Y++AA + G  N      G S I++P+G  +A  
Sbjct: 178 SAFTV-PTGKAHWEPLLRARAIETQSYVIAAAQAGPHNEKRRSYGHSIIVNPWGEVVAKL 236

Query: 225 --ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
               + P +  A++  + V ++R ++P+L      P
Sbjct: 237 GDEHQEPQIATADIDLDLVAKIRREMPLLRRNDLYP 272


>UniRef50_O94660 Probable hydrolase nit2 n=2 Tax=Schizosaccharomyces
           RepID=NIT2_SCHPO
          Length = 276

 Score =  119 bits (298), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 83/276 (30%), Positives = 131/276 (47%), Gaps = 23/276 (8%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEA--LLARDDHDADLSVKSAQL 59
           L A  Q   +    KN  IC  L++QAA   A     PEA   +A   H++D +++    
Sbjct: 3   LAAVAQLNSSGSILKNLAICKELISQAAAKGAKCIFFPEASDFIA---HNSDEAIELTNH 59

Query: 60  LE-GEFLGRLRRESKRNMMTTILTIHVPSTPGRAW---NMLVALQAGNIVARYAKLHLYD 115
            +  +F+  +R  + ++ +   + +H PS         ++ +    G I++RY+K HL+D
Sbjct: 60  PDCSKFIRDVRESATKHSIFVNICVHEPSKVKNKLLNSSLFIEPLHGEIISRYSKAHLFD 119

Query: 116 -----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                   ++ES     G  I P  +    KVG   C+D+RFPE A+     GA I+  P
Sbjct: 120 VEIKNGPTLKESNTTLRGEAILPPCKTPLGKVGSAICFDIRFPEQAIKLRNMGAHIITYP 179

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA 225
           +A+        HW  LL ARALD+ CY++A  + G  N      G S I+DP+G  IA  
Sbjct: 180 SAFTEK-TGAAHWEVLLRARALDSQCYVIAPAQGGKHNEKRASYGHSMIVDPWGTVIAQY 238

Query: 226 SEMPA---LIMAEVTPERVRQVRAQLPVLNNRRFAP 258
           S++ +   LI A++    V  VR  +P+L      P
Sbjct: 239 SDISSPNGLIFADLDLNLVDHVRTYIPLLRRNDLYP 274


>UniRef50_B0SIF2 Amidohydrolase n=3 Tax=Bacteria RepID=B0SIF2_LEPBA
          Length = 269

 Score =  119 bits (297), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 80/272 (29%), Positives = 128/272 (47%), Gaps = 33/272 (12%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLG 66
           Q   T+    N   C   + +AA   A +  LPE          + S   ++  +   LG
Sbjct: 9   QVTSTARVSNNLTKCRQFVEEAARAGAKVIGLPE----------NFSFMGSESEKQSLLG 58

Query: 67  RLR-------RESKRNMMTTILTIHVPST--PGRAWNMLVALQ-AGNIVARYAKLHLYDA 116
           ++        +E+   +   +L    P+    G+ +N  V +   G  V RY K+HL+DA
Sbjct: 59  QIEDETILFLKETASELGIYLLGGGFPTKAPSGKVFNTAVMINPKGEEVFRYHKVHLFDA 118

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                F  +ES   ++G ++  +++ E  K+    CYDLRFPEL  A + QG ++  LPA
Sbjct: 119 VVGDGFPYKESNHTESGEKVPEVIQTEYGKISSAICYDLRFPELFRALSKQGVDLCFLPA 178

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-------KNIGQSRIIDPFGVTIAA 224
           A+   P  E HW  LL ARA++   Y++A G+ G        K  G S II P+G  +A 
Sbjct: 179 AFTV-PTGEAHWHVLLRARAIENLMYVLAPGQTGTHDPHGKRKTFGHSLIISPWGEILAE 237

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
                   +A +  E++ ++R  LP LN+R+F
Sbjct: 238 LDHEEGFAIATMEMEKLSEIRNTLPSLNHRKF 269


>UniRef50_Q23ND3 Hydrolase, carbon-nitrogen family protein n=1 Tax=Tetrahymena
           thermophila SB210 RepID=Q23ND3_TETTH
          Length = 284

 Score =  118 bits (296), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 84/270 (31%), Positives = 135/270 (50%), Gaps = 18/270 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           LV   Q   T   ++N E     + QA E  A +   PEA        A+ + ++A+ ++
Sbjct: 8   LVGVVQMCSTHNKKQNMEFILQNLKQAHEKQAKICFFPEAFAMISRSFAE-TFENAEYID 66

Query: 62  GEFLGRLRRESKR-NMMTTI--LTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-- 115
           GE +  LR  +K+ N+  ++      +     +  N  + +   GNIV  Y KLHL+D  
Sbjct: 67  GEMINCLRDHAKKYNLWLSLGGFQERLKENDKKMGNTHIIIDNLGNIVQTYKKLHLFDIS 126

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL-ALAQALQGAEILVLPA 171
                 I ES     G+++  +++    ++GL  CYDLRFPEL  L    Q AEIL++P+
Sbjct: 127 IDTKNTISESSGYVFGDQVPNVVDSPAGRLGLSICYDLRFPELFRLLAVQQKAEILLVPS 186

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFG-VTIAAA 225
           A+ +    + HW TLL ARA++  C+++AA + G  N      G S +IDP+G V +   
Sbjct: 187 AFFK-KTGQAHWHTLLKARAIENQCFVIAAAQAGQHNDKRESYGHSLVIDPWGEVLLDMG 245

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            E   +   E+  E++  VR  LP +N+ R
Sbjct: 246 PEKLGIDFVEIDLEKIDTVRKGLPAINHIR 275


>UniRef50_B8D4L6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D4L6_DESK1
          Length = 272

 Score =  117 bits (292), Expect = 5e-25,   Method: Compositional matrix adjust.
 Identities = 54/160 (33%), Positives = 89/160 (55%)

Query: 96  LVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
           ++    G  +  Y+K+HL+DA+  +ES     GN    ++ ++G+K+G   CYDLRFPEL
Sbjct: 103 IIVTDRGEAIPVYSKMHLFDAYGFRESSFFKPGNVPGKIISIKGVKIGFTICYDLRFPEL 162

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRII 215
               AL G+EI+++ A WV+GP KE     L + RA + T Y+V A + G+  +G+S + 
Sbjct: 163 YRITALMGSEIIIVQAGWVKGPHKEEILDKLASIRAHENTVYIVLADQTGDMFVGRSGVF 222

Query: 216 DPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           +P+G          A +   +    + +VR +LPVL   +
Sbjct: 223 NPWGYRELDLGWREAYVEYTIDASLISEVREKLPVLQQSK 262


>UniRef50_Q9Y9L1 Putative hydrolase n=1 Tax=Aeropyrum pernix RepID=Q9Y9L1_AERPE
          Length = 268

 Score =  116 bits (291), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 84/250 (33%), Positives = 123/250 (49%), Gaps = 8/250 (3%)

Query: 10  VTSVWEKNAEI-CASLMAQAAENDASLFALPEAL-LARDDHDADLSVKSAQLLEGEFLGR 67
           V S  EK+A +     +A   +N   +   PE L L       D    +A+ LEG +   
Sbjct: 8   VASTREKDANLESVKRLASRVKNSPDIVLTPEYLMLDPTGLGRDAIYDAAEDLEGRWSRE 67

Query: 68  LRR--ESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESRR 124
           L +  ES  + +   L +  PS  GR  N  V   + G I+  Y K HL+DA+   ES  
Sbjct: 68  LSKIAESLGSCLLGHLFLKTPS--GRVANAAVLYSRDGGIIGVYRKTHLFDAYGYVESSF 125

Query: 125 VDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL-QGAEILVLPAAWVRGPLKEHHW 183
            + G+E+    +  G  +G+  CY+LRFPE+   Q+L  G +I ++PAAW RGP KE   
Sbjct: 126 TEPGDELWEPRKACGASIGVAICYELRFPEIFRTQSLVGGVDIFLVPAAWYRGPGKEEAL 185

Query: 184 STLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQ 243
           S L  ARA + T Y+  A   G   +G+S II P G T+A A     ++  E+    + +
Sbjct: 186 SVLSRARAQENTSYVAVASNAGANFVGRSMIIHPLGYTLAQAPPWEWVLEHEIDLREIER 245

Query: 244 VRAQLPVLNN 253
            R  LPVL +
Sbjct: 246 ARKSLPVLEH 255


>UniRef50_D0L1I4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Halothiobacillus neapolitanus c2
           RepID=D0L1I4_HALNC
          Length = 294

 Score =  116 bits (290), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 91/281 (32%), Positives = 136/281 (48%), Gaps = 30/281 (10%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +AA Q    + W +N  + A L++ AAE  A +  LPE L A   +  +L +      EG
Sbjct: 15  IAAIQLNGKATWAENQPVIARLVSDAAEAGAEVIVLPENLYAMPANPHEL-LALGLGAEG 73

Query: 63  E-----FLGRLRRESKRNMMTTILTIHVP--STPGRAWNMLVALQA-GNIVARYAKLHLY 114
           E     +L  L R     ++   L I     S  G+ W+    + + G I A+Y K+HL+
Sbjct: 74  ENAPLDWLQTLARFKGVWLVAGTLPIRADGGSNEGKLWSRSYVIDSKGEIQAKYDKIHLF 133

Query: 115 D-------------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL 161
           D             A + +ES +   G E+  L+E    ++G+  C+DLRFPEL      
Sbjct: 134 DVDVPPRRSAQSATAESYRESDQFLHGTELV-LVETPAGRLGMAICFDLRFPELFRRLTD 192

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGE-----CGNKNIGQSRIID 216
           QGAE + LP+A+     +  HW  LL ARA++   YMVA+ +      G K  G S ++D
Sbjct: 193 QGAEWICLPSAFTETTGRA-HWEPLLRARAIENQVYMVASAQVGVHASGRKTFGHSMVVD 251

Query: 217 PFGVTIAAASEM-PALIMAEVTPERVRQVRAQLPVLNNRRF 256
           P+G  +A A  +    +MAE+  E    VR Q PVL+ RR 
Sbjct: 252 PWGTVLANAKTLADCFVMAEIDAEAQAHVRQQFPVLDLRRL 292


>UniRef50_A5V962 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Sphingomonas wittichii RW1 RepID=A5V962_SPHWW
          Length = 268

 Score =  116 bits (290), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 66/170 (38%), Positives = 97/170 (57%), Gaps = 13/170 (7%)

Query: 96  LVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDL 150
           LV  + G  + RY+KLH +D       AI+ES  VD G+ I  ++++EG+KV L  CYDL
Sbjct: 96  LVFDRQGECIGRYSKLHRFDIDLPDGTAIRESDVVDRGDAIT-VVDIEGLKVALTICYDL 154

Query: 151 RFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK--- 207
           RFPEL  A    GA+++ +PAA+        HW  LL ARA++T CY+ A G+ G     
Sbjct: 155 RFPELFRALVDLGADLITVPAAFTF-QTGADHWEVLLRARAIETECYIAAPGQVGGFDDG 213

Query: 208 ---NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
              N G S IIDP+G  +  AS    +  A +  + ++ VRA++P+  +R
Sbjct: 214 KYLNFGHSMIIDPWGTVVGQASNGEGVASAVIDRDYIQTVRARIPLRKHR 263


>UniRef50_Q1PXD4 Similar to N-carbamoyl-D-amino acid hydrolase n=1 Tax=Candidatus
           Kuenenia stuttgartiensis RepID=Q1PXD4_9BACT
          Length = 277

 Score =  115 bits (289), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 86/267 (32%), Positives = 133/267 (49%), Gaps = 18/267 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +AA Q        KN      LM +A +  A L ALPE          +++  + +   G
Sbjct: 6   IAAIQMCSVHDRNKNLNTARVLMEKAVQKGARLIALPENFSFIGQERENITF-AEERETG 64

Query: 63  EFLGRLRRESKRNMMTTILTIHVP---STPGRAWNM-LVALQAGNIVARYAKLHLYDAF- 117
           E +  L++ S ++ +  I+   VP   S+  +  N  LV  Q+G I+  Y K+HL+D   
Sbjct: 65  EIVHFLKKFSMKHSVA-IIGGSVPLRSSSKAKVTNTCLVFDQSGVIIGSYDKIHLFDFHL 123

Query: 118 ----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES  V  G  I  + ++ G  +GL  CYDLRFPEL     L+G E+L  P+A+
Sbjct: 124 DDKTVYRESHYVKHGKHIETV-KLFGHIMGLCICYDLRFPELFRKLMLRGMEVLFAPSAF 182

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                K+ HW  LL ARA++  CY+VA  + G  N      G++ IIDP+G  +A   +M
Sbjct: 183 TMETGKD-HWEILLRARAIENQCYVVAPAQYGRHNDERISYGRTMIIDPWGRIMAQCQDM 241

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRR 255
             +I+ E+    + +VR +LP L + R
Sbjct: 242 EDVIVCEIDFAFLGEVRKRLPCLKHIR 268


>UniRef50_C1B562 Putative hydrolase n=2 Tax=Actinomycetales RepID=C1B562_RHOOB
          Length = 278

 Score =  115 bits (289), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 87/238 (36%), Positives = 120/238 (50%), Gaps = 17/238 (7%)

Query: 33  ASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMM----TTILTIHVPST 88
           A L  LPE L A    D D     A+ L+G FL  + R +KRN +     +I+     + 
Sbjct: 45  ADLVVLPE-LWAHGGFDYDTWTDRAEPLDGTFLETMSRAAKRNSIWLHAGSIIERENDTA 103

Query: 89  PGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNE--IAPLLEVEGMK--VG 143
             R WN  V     G I A Y K+H +  F+  E R + AG E     L    G +  VG
Sbjct: 104 SARLWNTSVVFDPDGEIRATYRKIHRF-GFSDGEPRLLTAGTEPVSTGLATAAGAETVVG 162

Query: 144 LMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMV---A 200
           L TCYDLRFPEL       G E+LV+PAAW R  ++  HW+ L  ARA++   Y+V    
Sbjct: 163 LSTCYDLRFPELYRELVGAGTEVLVIPAAWPRARVE--HWTALGRARAIENQTYVVQCNV 220

Query: 201 AGECGNKNI-GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
           AG  G+  + G S+I+ P G  +AAA +   +I A +    +R++R   PVL +RR  
Sbjct: 221 AGVDGDVALGGHSQIVAPDGTVVAAAGDSADMISATLELGSLRELRRTFPVLADRRLG 278


>UniRef50_B3E274 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=10 Tax=Desulfuromonadales RepID=B3E274_GEOLS
          Length = 262

 Score =  115 bits (288), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 65/174 (37%), Positives = 95/174 (54%), Gaps = 9/174 (5%)

Query: 86  PSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLM 145
           P+  GR +N +  +  G +VARY KLHL   F++    R   G +   L E    KVG++
Sbjct: 90  PADDGRVFNTIHVVDNGQMVARYRKLHL---FSLLGEDRAFKGGDSWCLAETSIGKVGVI 146

Query: 146 TCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG 205
            CYDLRFPEL+   AL+GA ++ +PA W +   ++ HW TLL ARA++   Y+V+   CG
Sbjct: 147 ICYDLRFPELSRRLALEGARVICVPAQWPKP--RQEHWRTLLRARAIENQLYIVSCNACG 204

Query: 206 NKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
                   G S +IDP G  +A A E    + A +  + +   RAQ+P   +RR
Sbjct: 205 QIGKLDFFGMSMVIDPKGEVLADAGEAACEVTATLDWQVMEAWRAQIPCFGDRR 258


>UniRef50_A5GT50 Possible nitrilase n=5 Tax=Bacteria RepID=A5GT50_SYNR3
          Length = 272

 Score =  114 bits (285), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 88/272 (32%), Positives = 135/272 (49%), Gaps = 24/272 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQ 58
            L AA Q   T   + N      L+  AA   A L  LPE  A L  ++   +L+   A 
Sbjct: 4   FLAAALQCTSTPDPDSNFAQIEELIDLAARRGAELVGLPENFAFLGAENKRLELAPTLA- 62

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM----LVALQAGNIVARYAKLHLY 114
               E   R      R     IL    P   G A       LV+ + G ++A Y K+HL+
Sbjct: 63  ----ERCSRFLVTMARRYQVAILGGGFPVPAGEAATFNRSELVS-RDGQVLATYDKIHLF 117

Query: 115 D-----AFAIQESRRVDAGNEIAPLLEVEGM-KVGLMTCYDLRFPELALAQALQGAEILV 168
           D          ES  + AG+ + P+ ++ G+ +VGL  CYD+RFPEL    A  GAE+L+
Sbjct: 118 DVDLPDGNTYTESDTITAGSSLPPVADLPGLCRVGLSICYDVRFPELYRHLAGAGAELLM 177

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIA 223
           +PAA+     K+ HW  LL ARA++ T Y++A  + G      ++ G + +IDP+G  +A
Sbjct: 178 VPAAFTAYTGKD-HWQVLLQARAIENTSYVLAPAQTGLHYGRRQSHGHALVIDPWGTVLA 236

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            A   P + +A +  + ++++RAQ+P L +RR
Sbjct: 237 DAGVGPGVAIAPIDTDHLQRIRAQMPSLRHRR 268


>UniRef50_A7IJX5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=101 Tax=Alphaproteobacteria RepID=A7IJX5_XANP2
          Length = 310

 Score =  114 bits (285), Expect = 3e-24,   Method: Compositional matrix adjust.
 Identities = 67/165 (40%), Positives = 93/165 (56%), Gaps = 11/165 (6%)

Query: 102 GNIVARYAKLHLYDA-FAIQESRRVDAG---NEIAPLLEVEGMKVGLMTCYDLRFPELAL 157
           G I+ARY K+H++D      ES R  +     E A L  V   + GL  CYDLRFP L  
Sbjct: 128 GEIIARYDKIHMFDVDLGNGESYRESSAYRPGERAILANVGAFRFGLTICYDLRFPSLYR 187

Query: 158 AQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQS 212
           A A  GA++L +P+A+ R P  E HW  LL ARA++   Y++AA      E G +  G S
Sbjct: 188 ALAEGGAQVLTVPSAFTR-PTGEAHWHVLLRARAIENGAYVLAAAQGGKHENGRETFGHS 246

Query: 213 RIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN-RRF 256
            ++DP+G  IA     P +I+AE+  + V   RA++P L+N RRF
Sbjct: 247 LVVDPWGRVIAEGGADPGVILAEIDLKEVAAARARIPSLSNGRRF 291


>UniRef50_C5DKM8 KLTH0F05984p n=2 Tax=Saccharomycetaceae RepID=C5DKM8_LACTC
          Length = 352

 Score =  114 bits (285), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 88/291 (30%), Positives = 145/291 (49%), Gaps = 40/291 (13%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEA--LLARD-DHDADLSVKSAQL 59
           +A GQ   +S  ++N  +  +L+ QA  +DA +   PEA   ++R   H  +L+ KS   
Sbjct: 56  IAIGQMCSSSSLDQNLGVVKTLIDQALASDAKVIFFPEAADYISRSASHSLELAEKSPAF 115

Query: 60  LEG--EFLGRLRRESKRNMMTTILTIHVPSTPG-------RAWNMLVAL-QAGNIVARYA 109
           +EG  + +  L  + ++ +  +I  +H+P+T         R  N L+ +   G I   Y 
Sbjct: 116 VEGLQKAIPELCSKHQKRIDVSI-GVHLPATSSDKSQHDTRLRNCLLYITHEGKIRQEYQ 174

Query: 110 KLHLYDAFA-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA 164
           KLHL+D        ++ES+ V  G  I  +L+    K+G   C+D+RFPELAL    +GA
Sbjct: 175 KLHLFDVEVPNGPILKESQAVQPGRAIPDVLDTPVGKLGSAICFDVRFPELALKLRSKGA 234

Query: 165 EILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI--------------- 209
           EIL  P+A+      E HW  L  ARALDT CY++  G+ G   +               
Sbjct: 235 EILCFPSAFTMK-TGEAHWQLLACARALDTQCYVIMPGQQGEHEVGIDPSKPGESPLKRV 293

Query: 210 --GQSRIIDPFGVTIAA---ASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
             G S ++ P+G  +AA   A+  P L++A++  +  +++R  +P+   RR
Sbjct: 294 SWGHSMVVGPWGKVVAAADPANNEPQLLLADLDLDAQKKIRRDMPLWEQRR 344


>UniRef50_Q557J5 Nitrilase homolog 1 n=1 Tax=Dictyostelium discoideum
           RepID=NIT1_DICDI
          Length = 291

 Score =  114 bits (284), Expect = 4e-24,   Method: Compositional matrix adjust.
 Identities = 82/275 (29%), Positives = 138/275 (50%), Gaps = 24/275 (8%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQLL 60
           +  GQ   T+  E N   C  ++ +A EN  +LF LPE  A ++   H  + S  +A+ L
Sbjct: 15  IGLGQITSTNNKEDNFRKCKEMIEKAVENKVNLFCLPECFAFISGGIHQFE-SRDNAEYL 73

Query: 61  E--GEFLGRLRRESKRNMM-TTILTIH--VPSTPGRA-WNM-LVALQAGNIVARYAKLHL 113
           +  G  + R +  +K+N +  ++   H  +   P    +N  L+    G IV  Y K+HL
Sbjct: 74  DQKGGIIERYKDLAKQNNIWLSLGGFHEKILDDPNDMIYNTHLIIDSNGVIVCEYRKMHL 133

Query: 114 YD------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +D         + ES+ V  GN++       G K+GL  CYDLRFPEL L+     A+IL
Sbjct: 134 FDVDIPSKGVKMNESKVVKGGNDLVVCDSPVG-KLGLSICYDLRFPELYLSLRRMDAQIL 192

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTI 222
           ++P+A+++    E HW  LL ARA++   Y++AA + G+ +      G S IIDP+G  +
Sbjct: 193 LVPSAFMKST-GEAHWKPLLQARAIENQTYVIAAAQTGDHHSKRSSYGHSMIIDPWGKVL 251

Query: 223 AA-ASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
                 +  +   ++  + +   R  +PV N+++ 
Sbjct: 252 HDLPDNLNDIAFVDIDLDYISTCRENIPVFNHKKL 286


>UniRef50_Q11146 UPF0012 hydrolase Rv0480c/MT0498 n=34 Tax=Actinomycetales
           RepID=Y480_MYCTU
          Length = 340

 Score =  114 bits (284), Expect = 5e-24,   Method: Compositional matrix adjust.
 Identities = 86/274 (31%), Positives = 132/274 (48%), Gaps = 27/274 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSV---KSA 57
           M +A  Q    +    N ++      +AA   A L   PEA + R      L V   + A
Sbjct: 61  MRIALAQIRSGTDPAANLQLVGKYAGEAATAGAQLVVFPEATMCR------LGVPLRQVA 114

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIV---ARYAKLHLY 114
           + ++G +   +RR +    +T I  +  P+  GR  N L+A   G      A Y K+HLY
Sbjct: 115 EPVDGPWANGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIHLY 174

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           DAF   ESR V  G E   ++ V+G++VGL  CYD+RFP L    A +GA+++ + A+W 
Sbjct: 175 DAFGFTESRTVAPGREPV-VVVVDGVRVGLTVCYDIRFPALYTELARRGAQLIAVCASWG 233

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGE--------------CGNKNIGQSRIIDPFGV 220
            GP K   W+ L  ARALD+  Y+ AAG+                   +G S +  P G 
Sbjct: 234 SGPGKLEQWTLLARARALDSMSYVAAAGQADPGDARTGVGASSAAPTGVGGSLVASPLGE 293

Query: 221 TIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
            + +A   P L++A++  + V   R ++ VL N+
Sbjct: 294 VVVSAGTQPQLLVADIDVDNVAAARDRIAVLRNQ 327


>UniRef50_D2RIK2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Acidaminococcus RepID=D2RIK2_ACIFE
          Length = 275

 Score =  113 bits (283), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 82/245 (33%), Positives = 124/245 (50%), Gaps = 24/245 (9%)

Query: 27  QAAENDASLFALPEAL--LARDDHDADLSVKSAQLLEG----EFLGRLRRESKRNMMTTI 80
           +AA   A L  LPE++  + RD        + A+ + G    + L  L RE    +    
Sbjct: 30  EAAARGARLVVLPESMNYIGRD------MAQEAEAIPGGPTFQRLSGLARELDLWLEAGS 83

Query: 81  LTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPL 134
           +    P  P R +N   +    G + A+YAKLH +D         +ES RV  G ++  +
Sbjct: 84  IYESNPEDPARPFNTTFLICPDGTLAAKYAKLHPFDVVLPNGVTSRESDRVCPGKKLT-V 142

Query: 135 LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDT 194
            E +  KVGL  CYD+RF E+    AL+GA++  +PA +     K+H W  LL ARA++ 
Sbjct: 143 AETDLGKVGLGICYDIRFGEMFRIMALEGAKLFAVPANFTVNTGKDH-WEVLLRARAIEN 201

Query: 195 TCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPV 250
            CY++A  + G K      G S ++DP+G  IA AS+ P +I AE+  + V +VR     
Sbjct: 202 ECYVIAPNQMGKKPRFTAYGNSLMVDPWGTVIARASDKPGVITAEIDLDYVTKVRQSTFT 261

Query: 251 LNNRR 255
           L+NRR
Sbjct: 262 LDNRR 266


>UniRef50_Q2QQ94 Os12g0502500 protein n=5 Tax=Spermatophyta RepID=Q2QQ94_ORYSJ
          Length = 323

 Score =  113 bits (283), Expect = 6e-24,   Method: Compositional matrix adjust.
 Identities = 80/258 (31%), Positives = 127/258 (49%), Gaps = 19/258 (7%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           + N   C+ L  +AA +       PE        D + S+K A+ L+G  + R    +K 
Sbjct: 60  DANYATCSRLAKEAASSGVKFLCFPEVFSFIGSKDGE-SIKIAEPLDGPIMQRYCSLAKE 118

Query: 75  NMMTTILTIHVPSTPGRA--WNMLVALQ-AGNIVARYAKLHLYDA-----FAIQESRRVD 126
           + M   L       P  +  +N  V +  +G I + Y K+HL+D         +ESR   
Sbjct: 119 SSMWLSLGGFQEKGPDDSHQYNTHVLIDDSGEIRSSYRKIHLFDVDVPGNMVYKESRFTT 178

Query: 127 AGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQG-AEILVLPAAWVRGPLKEHHWST 185
           AG+ +  +    G ++GL  CYDLRFPEL      +  A++L++P+A+ +    E HW  
Sbjct: 179 AGDTVVAVDSPFG-RLGLTVCYDLRFPELYQCLRFKHQAQVLLVPSAFTK-VTGEAHWEI 236

Query: 186 LLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE--MPALIMAEVTP 238
           LL ARA++T CY++AA + G  N      G S IIDP+G  IA   +       +A+V  
Sbjct: 237 LLRARAIETQCYVIAAAQAGKHNEKRESYGDSIIIDPWGTVIARLPDRLSTGFAVADVDL 296

Query: 239 ERVRQVRAQLPVLNNRRF 256
            +V  VR ++P+  +R+F
Sbjct: 297 SKVEAVRTKMPISEHRKF 314


>UniRef50_C7N2Y0 Predicted amidohydrolase n=1 Tax=Slackia heliotrinireducens DSM
           20476 RepID=C7N2Y0_SLAHD
          Length = 270

 Score =  111 bits (277), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 68/229 (29%), Positives = 118/229 (51%), Gaps = 8/229 (3%)

Query: 35  LFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPG-RAW 93
           L   PE  +     D++   + ++ L+G F   +   + R+ +  +  I   +  G + +
Sbjct: 36  LLVFPENFMLPGILDSEGVKEISEPLDGPFARAMADIALRHHLWIVYVIFEENPDGGQPF 95

Query: 94  NMLVALQAGNIV-ARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRF 152
           N  V + A  +    Y K HLYDA  + ES R  AG+++   ++     +G+  CYDLRF
Sbjct: 96  NTAVTVDAEGVQRGAYRKCHLYDAHGVLESDRSVAGDQLPQPVDTPFGPLGVAICYDLRF 155

Query: 153 PELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQS 212
           PE+A A A+ G ++++ P+AW  GP K  HW+TLL ARA++   ++      G +  G++
Sbjct: 156 PEVARALAVAGCKLVLFPSAWNAGPRKVKHWTTLLRARAIENELFVAGICHAGKRYTGKT 215

Query: 213 RIIDPFGVTIAAA-----SEMPA-LIMAEVTPERVRQVRAQLPVLNNRR 255
            + DP G  +A+A        P  L++  +  + V   R  +PVL++RR
Sbjct: 216 LVADPLGRIVASARGSSKGNAPQDLVICTIDTDAVESARDAMPVLDHRR 264


>UniRef50_C8RSM4 Carbon-nitrogen hydrolase n=3 Tax=Corynebacterium
           RepID=C8RSM4_CORJE
          Length = 320

 Score =  110 bits (275), Expect = 4e-23,   Method: Compositional matrix adjust.
 Identities = 89/285 (31%), Positives = 129/285 (45%), Gaps = 37/285 (12%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q       E N       +A  A N A L   PEA +   D+    +V  AQ L
Sbjct: 16  MRIAVIQMKAEPDVEANLARILKYIASGAANGADLVVFPEAAMFPFDNGRLDTV--AQPL 73

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPS-----TPG-----------------RAWNMLVA 98
           +G F   +   +K++  T ++ +  P+     TP                  R  N  + 
Sbjct: 74  DGPFAQAIIDTAKKHGTTAVVGMFTPADTVYRTPSGQLVEEQPSDSPEANQFRRVNNTLL 133

Query: 99  LQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALA 158
           +   + V  Y K+H YDAF  +ES  V  G     +++V G+ VGL TCYD+RFP   +A
Sbjct: 134 VAGPDYVTHYDKIHTYDAFGYRESDTVKPGKRRV-VIDVGGVGVGLATCYDIRFPGHFVA 192

Query: 159 QALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC------------GN 206
            A  GA+++V+P++W  GP K   W  L AARALD+  Y++AAG              G 
Sbjct: 193 MAAAGAKVMVVPSSWADGPGKLEQWRELTAARALDSASYLIAAGMARPGSPERYGTADGP 252

Query: 207 KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVL 251
             IG S  I P G  +A       ++  ++ P  V +VR  LPVL
Sbjct: 253 TGIGHSVAIGPNGARLAETGYAAQVLTIDIDPNYVDKVRKTLPVL 297


>UniRef50_Q2NHR0 Predicted amidohydrolase n=1 Tax=Methanosphaera stadtmanae DSM 3091
           RepID=Q2NHR0_METST
          Length = 274

 Score =  110 bits (275), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 77/269 (28%), Positives = 121/269 (44%), Gaps = 25/269 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q  V    + N E    L+ +A+ N A L  LPE      D+      K  +  E 
Sbjct: 6   IATCQMNVVDNKDTNIEHAIQLIKKASSNGAKLITLPEMFNTPYDNS-----KFIEYCEE 60

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-----AGNIVARYAKLHLYD-- 115
           E   +     +       + +   S P +  N L          G I+ ++ K+H++D  
Sbjct: 61  ETTSKTLNSMQDIAREENIYLQSGSIPEKESNHLYNTAYLINPKGKIIGKHRKMHMFDID 120

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                  ES  +  G+ +   ++     + +  CYD+RFPEL        ++I++LP A+
Sbjct: 121 TDNMKFTESDTLTPGDSVT-TIKTPLANISIAICYDIRFPELWTLMNKNNSDIILLPGAF 179

Query: 174 VR--GPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS 226
            +  GPL   HW TL+ ARA+D  CY+VA      +N      G S I++P+G  IA A 
Sbjct: 180 NKTTGPL---HWETLIKARAIDNQCYVVATSPSQIENPYYVAWGHSMIVNPWGKIIAKAH 236

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           E   ++ A +T   +  VR Q+PVL NRR
Sbjct: 237 ENEEILYANITQSSLSSVRNQIPVLTNRR 265


>UniRef50_Q0HEI5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=21 Tax=Shewanella RepID=Q0HEI5_SHESM
          Length = 282

 Score =  110 bits (275), Expect = 5e-23,   Method: Compositional matrix adjust.
 Identities = 62/172 (36%), Positives = 94/172 (54%), Gaps = 14/172 (8%)

Query: 102 GNIVARYAKLHLYDAFA------IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
           G+ + +Y KLHL+D          +ES     GN I+ +++    K+GL  CYDLRFP+L
Sbjct: 111 GDTLGQYDKLHLFDVDVADGTKQYRESETFCPGNHIS-VIDTPFGKIGLTICYDLRFPDL 169

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN------I 209
             A  L GAEI+ +P+A+ +    E HW  LL ARA++T C+++AA + G  N       
Sbjct: 170 FRALRLAGAEIITVPSAFTK-VTGEAHWQVLLQARAIETQCFILAAAQWGAHNEGSRETW 228

Query: 210 GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           GQS +I P+G  IA        + A++    V  +R+++PV  + RF  P L
Sbjct: 229 GQSMVIGPWGEVIAEQKTGTGWVHADIDVAEVHSIRSKMPVAQHNRFTAPNL 280


>UniRef50_D2VM50 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VM50_NAEGR
          Length = 300

 Score =  110 bits (274), Expect = 7e-23,   Method: Compositional matrix adjust.
 Identities = 77/273 (28%), Positives = 127/273 (46%), Gaps = 34/273 (12%)

Query: 17  NAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNM 76
           N  +C  L+ +A+E+ ASL   PE          +    S  L    F        K ++
Sbjct: 17  NFGVCEKLIKEASEHKASLICFPECFAFMGTSATETIANSGSLDSELFKSYQDLARKYSI 76

Query: 77  MTTILTIHVPST--PGRAWNMLVALQA-GNIVARYAKLHLYD----AFAIQESRRVDAGN 129
             +    H  S+  P + +N  + +   G I+  Y K+HL+D       ++ES   + G 
Sbjct: 77  NISYGGYHEKSSNDPHKIFNSHILVNNNGEIINVYRKVHLFDLNTEKVKLKESEITEFGK 136

Query: 130 EI----APLLEVEGMKVGLMTCYDLRFPELA-LAQALQGAEILVLPAAWVRGPLKEHHWS 184
           ++      L+    +K+GL  CYDLRFPEL  L + +  A+IL++PAA+ +   +  HW 
Sbjct: 137 DLLVDDGGLIFSNDLKIGLSICYDLRFPELYILLRKMNNAKILLVPAAFTKHTGELGHWK 196

Query: 185 TLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTI---AAASEMPALIMAEV 236
           TLL ARA++  CY++A+ + G  N+     G S +IDP G  I    +  E   L + E 
Sbjct: 197 TLLMARAIENQCYVIASAQVGTHNLKRQSYGHSLVIDPLGKIILDLGSQEETFDLDIQEK 256

Query: 237 TP--------------ERVRQVRAQLPVLNNRR 255
            P                +++VR  +PV +++R
Sbjct: 257 EPFEGKLGFVEIDDWISNIKKVREGMPVFDHKR 289


>UniRef50_Q2RWF2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Rhodospirillaceae RepID=Q2RWF2_RHORT
          Length = 279

 Score =  108 bits (271), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 61/164 (37%), Positives = 92/164 (56%), Gaps = 12/164 (7%)

Query: 102 GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G I  RY K+H++D       + +ES    AG+  A  L++   ++GL  CYDLRFP L 
Sbjct: 111 GAIRGRYDKIHMFDVNLADGESYKESSTFQAGSR-AVALDIPFGRLGLSICYDLRFPHLF 169

Query: 157 LAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQ 211
            A A  G   L +PAA+ R    E HW  L   RA++T CY+++  + G      +  G 
Sbjct: 170 RALAKAGCHYLTIPAAFTR-TTGEAHWHVLQRTRAIETGCYVISPAQTGTHAEGRQTYGH 228

Query: 212 SRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           + IIDP+G  +A A E P +I+A++ PE+V + RA +P L++ R
Sbjct: 229 ALIIDPWGRVLADAGEAPGIILAKIDPEKVVEARAMVPSLSHDR 272


>UniRef50_C1GYG0 Hydrolase n=1 Tax=Paracoccidioides brasiliensis Pb01
           RepID=C1GYG0_PARBA
          Length = 276

 Score =  108 bits (269), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 73/223 (32%), Positives = 116/223 (52%), Gaps = 21/223 (9%)

Query: 17  NAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE----GEFLGRLRRES 72
           N   C  L+ +A E  A    LPEA     D+ A    ++  L +      F+  L++E+
Sbjct: 4   NLSQCQILVKKAVEAGAKALFLPEA----SDYIATSPSETVSLAQPVQRSAFVLGLQKEA 59

Query: 73  KRNMMTTILTIHVPSTPG-RAWNMLVAL-QAGNIVARYAKLHLYD-----AFAIQESRRV 125
           + + +   + IH P+  G +  N L+ + + G I  RY KLHL+D        ++ES+ V
Sbjct: 60  RESKIPINVGIHEPAQGGEKVKNTLIWIDEVGEITQRYQKLHLFDVDIKDGPVLKESKSV 119

Query: 126 DAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWST 185
           + G  I P       +VGL  C+DLRFPE++L+   Q A+I+  P+A+   P  + HW  
Sbjct: 120 EKGMGILPPFFTPVGRVGLSICFDLRFPEVSLSLRRQSAQIITYPSAFTV-PTGQAHWEP 178

Query: 186 LLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIA 223
           LL ARA++T  Y++AA + G  N      G S I++P+G  +A
Sbjct: 179 LLRARAIETQSYVIAAAQAGVHNSKRVSYGHSMIVNPWGEVVA 221


>UniRef50_Q1LEX6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Cupriavidus metallidurans CH34
           RepID=Q1LEX6_RALME
          Length = 278

 Score =  108 bits (269), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 64/164 (39%), Positives = 91/164 (55%), Gaps = 13/164 (7%)

Query: 102 GNIVARYAKLHLYDAFAIQESRRVDAGNEIAP-----LLEVEGMKVGLMTCYDLRFPELA 156
           G I ARY K+HLYDA    +  R  A  + AP      ++  G+ +GL  CYDLRF EL 
Sbjct: 106 GGIAARYRKVHLYDAVVNGKPYRESA--DFAPGDGLHTVDAAGLTLGLSICYDLRFGELY 163

Query: 157 LAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQ 211
                +GA +L++PAA+     ++ HW TLL ARA++  CY++AA + G        +G+
Sbjct: 164 RTLRARGANVLLVPAAFNVHTGRD-HWETLLRARAIENQCYVIAAAQIGGPGPALPCLGR 222

Query: 212 SRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           S IIDP+G  +A   +    I AE+  ERV  +R  LP   +RR
Sbjct: 223 SMIIDPWGTVLACMPDTTGFITAELDTERVAGLREALPAWEHRR 266


>UniRef50_A5G317 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Alphaproteobacteria RepID=A5G317_ACICJ
          Length = 284

 Score =  107 bits (268), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 74/211 (35%), Positives = 106/211 (50%), Gaps = 22/211 (10%)

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNM-LVALQAGNIVARYAKLHLYD----- 115
           EFL    RE+ R     +    +    G R +N  LV    G  +ARY K+HL+D     
Sbjct: 80  EFL----RETARRHRIHVHGGSIGEQGGDRLYNTTLVFDPDGREIARYRKIHLFDITTPD 135

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +ES    AG+ +     + G+ VGL  CYD+RFPEL LA    GA+++++PAA+  
Sbjct: 136 GQGYRESATYGAGDAVV-TCRIGGLTVGLSICYDMRFPELYLALHRAGADLIMVPAAFTL 194

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK---------NIGQSRIIDPFGVTIAAAS 226
              K+ HW  LL ARA++T C++ AA   G             G S I DP+G  +A  S
Sbjct: 195 QTGKD-HWDVLLRARAIETQCWIAAAACVGPHRDGRGETRFTYGNSLIADPWGSIVARVS 253

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
           + P    A + P R  +VR  +PVL +R+ A
Sbjct: 254 DGPGFATARIDPARGAKVRRDMPVLEHRKLA 284


>UniRef50_B5JWE9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=gamma proteobacterium HTCC5015
           RepID=B5JWE9_9GAMM
          Length = 282

 Score =  107 bits (268), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 84/270 (31%), Positives = 120/270 (44%), Gaps = 16/270 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L+A  Q   T   E N      L+A AAE  A +  LPE      D        +    +
Sbjct: 11  LIACVQMTTTDSVEHNLATAQRLVANAAERGAQIVVLPETFAFMGDEITQQFGVAEAFGD 70

Query: 62  GEFLGRLRRESKRNMM----TTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYD-- 115
           G     +   +K N +     TI   H           LV   +G   ARY K+HL+D  
Sbjct: 71  GPIQTAVADWAKSNHVWIVAGTIPLRHESDRERVRAACLVFDDSGQCQARYDKVHLFDVE 130

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                + +ES     G+EIA +L+    ++G+  CYDLRFPEL  AQ   G E  VLP+A
Sbjct: 131 LPTGESYKESSVFLPGDEIA-VLDTPLGRMGVAVCYDLRFPELFRAQLDMGMEFCVLPSA 189

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++  CY  AA + G      +  G S I+DP+G  +   +E
Sbjct: 190 FTEA-TGQAHWLPLLQARAVENLCYFAAAAQVGEHGSGRRTHGHSVILDPWGQVVDQLAE 248

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
              +++  +  E  R  RA  P L +RR +
Sbjct: 249 GEGVVVGSIDMEHQRLTRANFPALQHRRLS 278


>UniRef50_B0TEY4 Hydrolase, carbon-nitrogen family n=1 Tax=Heliobacterium
           modesticaldum Ice1 RepID=B0TEY4_HELMI
          Length = 265

 Score =  107 bits (268), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 89/266 (33%), Positives = 116/266 (43%), Gaps = 21/266 (7%)

Query: 1   MLVAAGQFAVTSVWEK-NAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M V   QF V S   K N E  A  MA+A E    +  LPE      D      V  A L
Sbjct: 1   MKVGLLQFNVCSGDRKANVETVARYMAEAREACPDVLVLPEMWTTGYDW-----VNLAAL 55

Query: 60  LE-GEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQ-AGNIVARYAKLHLYDA 116
            + GE  G L     +    TI+    P    GR  N L A    G  +  Y K+HL+  
Sbjct: 56  ADDGESFGALLACWAKETGATIVGGSSPVGANGRYANTLYAYTPEGERILSYEKVHLFGM 115

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
               E R + AG+       +  +  G + CYDLRFPE      L G EIL +PA W   
Sbjct: 116 MG--EERHLAAGSSTGNFC-IGAVPCGAVICYDLRFPEWIRKTVLAGCEILFIPAQW--- 169

Query: 177 PLKE-HHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPA 230
           PL    HW  LL ARA++  CY++A    G         G S +IDP+GV    A E   
Sbjct: 170 PLSRLDHWRILLQARAIENQCYVIACNRTGRDEQGVAFAGHSMVIDPWGVIAVEAGEEEG 229

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRF 256
            I  E+  ++V +VR ++ V  +RR 
Sbjct: 230 WIWGEIDRDKVERVRRKMTVFADRRL 255


>UniRef50_C8S929 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Archaeoglobaceae RepID=C8S929_FERPL
          Length = 250

 Score =  107 bits (268), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 79/257 (30%), Positives = 131/257 (50%), Gaps = 16/257 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M+VA  Q  +    E N     SL+ +A +++A +  LPEA       +    V+S +  
Sbjct: 1   MIVAVAQQRIVEDVEVNKMKALSLVKRAIQHEAKIVVLPEASNTGLFPENFGKVRSLE-- 58

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
             E L  + + S+R  +  I  + V  + G  +N +  +  G ++ +Y+K+ L   F + 
Sbjct: 59  --EELDLILKLSERKDILVIAGV-VERSEGNLFNSVALIYRGEVIGKYSKILL---FPLN 112

Query: 121 ESRR-VDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           E R+ + AG E+  + E +  K+G++ CY++RFPE+A      GAEIL +PA +   P +
Sbjct: 113 EERKYLTAGKELK-VFETDFGKIGVLVCYEVRFPEMARKLMKMGAEILAVPAEF---PAE 168

Query: 180 E-HHWSTLLAARALDTTCYMVAAGECGNKNI--GQSRIIDPFGVTIAAASEMPALIMAEV 236
              HW TLL ARA++   Y++ A          G S I+DP G  +  A  +  +I+ EV
Sbjct: 169 RIEHWRTLLRARAIENQFYVLGANCVSPDGFYGGNSMIVDPMGNVVNEAGNLQEIIIGEV 228

Query: 237 TPERVRQVRAQLPVLNN 253
             E VR+VR + P L +
Sbjct: 229 NLEYVRRVREEYPFLKD 245


>UniRef50_C7LN61 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfomicrobium baculatum DSM 4028
           RepID=C7LN61_DESBD
          Length = 270

 Score =  106 bits (265), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 65/194 (33%), Positives = 103/194 (53%), Gaps = 9/194 (4%)

Query: 67  RLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQESRRV 125
           RL   ++ + +  +  + +P   G A N LVA    G+I+ARY K+HL+ A    E+   
Sbjct: 66  RLMALAREHDICLVCGVCLPGPDGLA-NALVAFGPTGDILARYRKIHLFTATDADETEVF 124

Query: 126 DAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWST 185
             G+EI    + EG++ GL  CYDLRFPEL   QAL G + ++L +AW +   +   W T
Sbjct: 125 SPGSEIV-CFDFEGVRFGLSVCYDLRFPELYRVQALHGCQAMLLASAWPK--RRIDIWQT 181

Query: 186 LLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALIMAEVTPERV 241
           L AARAL+  C+++ A   G++      G+S  + P G    A+++   +I   V    +
Sbjct: 182 LCAARALENQCFLLGANRIGDQGAFPFGGRSLFVTPGGEITLASADQEGVITGTVDLAEL 241

Query: 242 RQVRAQLPVLNNRR 255
             +R  +P L +RR
Sbjct: 242 AAIRQNIPALAHRR 255


>UniRef50_A6UCF8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Rhizobiales RepID=A6UCF8_SINMW
          Length = 285

 Score =  106 bits (264), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 91/274 (33%), Positives = 124/274 (45%), Gaps = 57/274 (20%)

Query: 16  KNAEICASLMAQAAENDASLFALPE--ALLARD---------DHDADLSVKSAQLLEGEF 64
           +NAE  A L+ +AA   A     PE    + RD         D   D+ V+ A  L GE 
Sbjct: 18  RNAETMAELVREAALRGAGYVQTPEMTGAIQRDRSGLRSILRDEANDIVVRKAARLAGEL 77

Query: 65  LGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVAR-------------YAKL 111
                           + +HV STP       +AL  G I  R             Y K+
Sbjct: 78  A---------------IYLHVGSTP-------IALADGKIANRGFLFGPDGAKICEYDKI 115

Query: 112 HLYDA-FAIQESRRVDAG---NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           H++D      ES R  A       A + ++   K+G   CYD+RFPEL   QA+ GAEI+
Sbjct: 116 HMFDVDLENGESWRESAAYHPGATARIADLPFGKLGFSICYDVRFPELFRQQAVAGAEIM 175

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTI 222
            +PAA+ R    E HW  LL ARA++   ++VAA      E G +  G S IIDP+G  +
Sbjct: 176 SVPAAFTR-QTGEAHWEILLRARAIENGLFVVAAAQGGTHEDGRETFGHSMIIDPWGRVL 234

Query: 223 AAASEM-PALIMAEVTPERVRQVRAQLPVLNNRR 255
           A A      +I+AE+ P  V   RA++P L N R
Sbjct: 235 AQAGRTGEEIIIAEIDPLAVHTARAKIPNLKNAR 268


>UniRef50_A3CTE8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Methanoculleus marisnigri JR1 RepID=A3CTE8_METMJ
          Length = 265

 Score =  106 bits (264), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 77/226 (34%), Positives = 105/226 (46%), Gaps = 11/226 (4%)

Query: 34  SLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAW 93
           SL   PE  +        +   S + L+G       R ++ N +    +I       R  
Sbjct: 36  SLICFPEQFVT--GWSPKVPPGSGEPLDGPLTAAFARIAEENGIAVAGSIVEAGLENRPK 93

Query: 94  NMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRF 152
           N  V L + G ++A YAK+HL+      E R   AG+ IA    V+G+K G+  CYDLRF
Sbjct: 94  NTTVVLDEDGELLAAYAKIHLFSPEG--EDRYYTAGDRIA-TFTVDGVKFGIAVCYDLRF 150

Query: 153 PELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVA---AGECGNKNI 209
           PEL    A+ G E +++PAAW    L   HW TLL ARAL+   Y+     AG  G    
Sbjct: 151 PELFRIYAIAGVECMLVPAAWPCSRLS--HWETLLPARALENRYYVTGVNTAGRPGAPCC 208

Query: 210 GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G S   DP G  I         I  EV P  V + ++ LP L++RR
Sbjct: 209 GGSLAADPDGTVIGRCGAGEEAISIEVDPVAVHEAQSSLPSLSDRR 254


>UniRef50_A1HPP3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HPP3_9FIRM
          Length = 259

 Score =  105 bits (262), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 76/249 (30%), Positives = 126/249 (50%), Gaps = 17/249 (6%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           E N +   +++ Q A+  A LF LPE  L    +  D  +K  +   G  +  L++ +K 
Sbjct: 16  EANRQKALAMLEQGAKAGAKLFVLPE--LWTTGYVLDQLLKIGEPDGGPTVKMLQQFAKD 73

Query: 75  NMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQESRRVDAGNEIAP 133
           N +  +         G+ +N +  +  AG +V +Y+K+HL     + E + +  G+    
Sbjct: 74  NGVEIVGGSIAEIRDGKVYNTIYVIDSAGEVVGKYSKIHLVPM--MDEEKYLTPGDRQG- 130

Query: 134 LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARA 191
           L ++   K G + CYDLRF EL  A AL+GAE+L +PA W  +RG     HW  L  ARA
Sbjct: 131 LFDLSFGKAGGIVCYDLRFTELTRALALKGAEVLFIPAEWPAIRG----RHWLILSQARA 186

Query: 192 LDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEM-PALIMAEVTPERVRQVRA 246
           ++   ++VA    G    N   G S ++ P+G  +A  SE    +I+A++    V ++R 
Sbjct: 187 IENQMFVVAVNRVGRDHNNTFFGHSLVVSPWGEVLAEGSETEEQVIIADIDLGMVPEIRR 246

Query: 247 QLPVLNNRR 255
           ++PV  +RR
Sbjct: 247 KVPVFADRR 255


>UniRef50_Q28IE5 Omega-amidase NIT2 n=42 Tax=cellular organisms RepID=NIT2_XENTR
          Length = 276

 Score =  105 bits (262), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 76/262 (29%), Positives = 121/262 (46%), Gaps = 19/262 (7%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLG 66
           QF V+ V  +N      L+ +AA+  A + ALPE       +      + A+ + GE   
Sbjct: 10  QFLVSPVKSENLNRACKLIKEAAQKGAQIVALPECF--NSPYGTKYFPEYAEKIPGESTE 67

Query: 67  RLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-----AFAIQ 120
           RL + +K   +  I         G+ +N        G ++ ++ K+HL+D         Q
Sbjct: 68  RLSQVAKECGIYLIGGSIPEEDSGKLYNTCAVFGPDGTLLVKHRKIHLFDIDVPGKIRFQ 127

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPL 178
           ES  +  G+  + + E    KVG+  CYD+RF ELA   + +G ++LV P A+    GP 
Sbjct: 128 ESETLSPGDSFS-VFETPYCKVGVGICYDIRFAELAQLYSKKGCQLLVYPGAFNMTTGPA 186

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAASEMPALIM 233
              HW  L  ARALD   Y+  A    ++       G S I+ P+G  IA A     +I 
Sbjct: 187 ---HWELLQRARALDNQVYVATASPARDEKASYVAWGHSTIVSPWGEVIAKAGSEETVIS 243

Query: 234 AEVTPERVRQVRAQLPVLNNRR 255
           A++  E + ++R Q+P+   RR
Sbjct: 244 ADIDLEYLAEIREQIPIRRQRR 265


>UniRef50_Q220F6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Burkholderiales RepID=Q220F6_RHOFD
          Length = 270

 Score =  105 bits (261), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 90/269 (33%), Positives = 135/269 (50%), Gaps = 20/269 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +AA Q    +  ++N +I   L+AQAA   A L  LPE      +HD D         
Sbjct: 1   MKIAAIQMVSGANLQRNLDIAGQLLAQAAAQGAELAVLPEYFCLMGEHDTDKLKIQETCG 60

Query: 61  EG---EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLY--- 114
            G   +FL R  R+    ++   L I   +      + LV    G  VARY K+HL+   
Sbjct: 61  SGPIQDFLSRCARDLGLWIVGGTLPISTTAAERVRNSSLVFDATGQCVARYDKIHLFRFD 120

Query: 115 -DAFAIQESRRVDAGNEIAP--LLEVEG--MKVGLMTCYDLRFPELALAQALQGAEILVL 169
                  E+R ++AG +     L   +G   ++GL  CYDLRFPEL    A   A++L++
Sbjct: 121 NGVECYDEARVLEAGTQAVTFDLASCDGNTYRIGLSICYDLRFPELYRQLA---ADVLLV 177

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAA 224
           P+A+      + HW  LL ARA++   Y++AA + G      +  G S +IDP+G  +A 
Sbjct: 178 PSAFTF-TTGQTHWEVLLRARAIENLAYVIAAAQGGVHDNRRRTWGHSMMIDPWGQILAQ 236

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNN 253
            +  PA+I+AEVT E ++  RA+LP LN+
Sbjct: 237 QAGGPAVIVAEVTQEFLQSARARLPALNH 265


>UniRef50_A7I641 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Candidatus Methanoregula boonei 6A8
           RepID=A7I641_METB6
          Length = 265

 Score =  105 bits (261), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 74/254 (29%), Positives = 118/254 (46%), Gaps = 17/254 (6%)

Query: 10  VTSVWE---KNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLG 66
           ++ VWE   +  E   +   +AA   A+L + PE      D     S K+   + G  + 
Sbjct: 8   ISGVWEAPDETLEQVETCFFRAAREGAALISFPEQFATGWD---PCSTKNTGGISGTVVN 64

Query: 67  RLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRV 125
            LR  +K++ +  I +      P +  N  +A+ + G I+  YAK+HL+     +E +  
Sbjct: 65  GLRELAKKHKIAVIGSFRETCLP-KPRNTAIAIDRNGTILTTYAKIHLFTPG--REDQAF 121

Query: 126 DAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWST 185
             G  +A    +EG+++GL  CYDLRFPE+      +G   +++PAAW +  LK  HW  
Sbjct: 122 SPGTGLA-TFALEGVQIGLAICYDLRFPEIFRLYRQRGVHAVIVPAAWPKSRLK--HWEL 178

Query: 186 LLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALIMAEVTPERV 241
            + +RA +   Y+      G   +    G S   DP G  IA A     L+  E+ P  V
Sbjct: 179 FIQSRAAENQMYIAGVNTSGTNPVDQYAGASMTADPHGTIIARAGTEQELLYYEIDPLIV 238

Query: 242 RQVRAQLPVLNNRR 255
            Q R   PV N+R+
Sbjct: 239 EQARRDFPVENDRK 252


>UniRef50_Q2JDM2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=43 Tax=cellular organisms RepID=Q2JDM2_FRASC
          Length = 404

 Score =  105 bits (261), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 83/250 (33%), Positives = 121/250 (48%), Gaps = 13/250 (5%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESK- 73
           E  A+    ++ +  +  A L  LPE  +    H  D     A+ L G  +  LR  ++ 
Sbjct: 18  ENAADRVRRVLGEIRQTQADLVVLPELWVTGYFH-FDRYEAEAEALTGPTVTALREAARE 76

Query: 74  RNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIA 132
           R       +I   S  GR +N  V +   G I   Y K+HL+  +   E+R +  G  + 
Sbjct: 77  RGCHLVAGSIVERSADGRLFNTTVLIGPDGMIRHAYRKVHLF-GYGSAEARLLTPGATVG 135

Query: 133 PLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL-KEHHWSTLLAARA 191
            +    G+ VGL TCYDLRFPEL    A  GAEI+V+ +AW   PL +  HW  L   RA
Sbjct: 136 TVPTELGI-VGLATCYDLRFPELFRLLAEGGAEIVVVVSAW---PLARLDHWRVLTRTRA 191

Query: 192 LDTTCYMVAAG----ECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQ 247
           ++   Y+VA      + G +  G S ++DP+G  +A A   P  + AE+ P R   VRA+
Sbjct: 192 IENQVYLVACNAAGRQAGREMAGASVVVDPWGEVLAEAGPRPTTVRAELDPSRPAAVRAE 251

Query: 248 LPVLNNRRFA 257
            PVL +RR  
Sbjct: 252 FPVLTHRRLG 261


>UniRef50_D0LZ94 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Bacteria RepID=D0LZ94_HALO1
          Length = 296

 Score =  104 bits (260), Expect = 2e-21,   Method: Compositional matrix adjust.
 Identities = 87/285 (30%), Positives = 140/285 (49%), Gaps = 30/285 (10%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE- 61
           +AA Q       +KN E+C   +A AA   A +  LPE   A   H     + +A+LL+ 
Sbjct: 12  LAALQMCAGDDRDKNLELCDRQVAAAASAGAEMVVLPENF-AYLGHSEGDRMAAAELLDE 70

Query: 62  ---GEFLGRLRRESKRNMMTTILTIHVPSTPGR-----------AWNMLVALQAGN-IVA 106
              G  L  L+R +  + +  +        P R           A+N  V +  G  +V+
Sbjct: 71  REPGPILAALKRMATVHGVWLVGGGMAERIPEREVKDGIDPDKQAFNTCVVVAPGGALVS 130

Query: 107 RYAKLHLYDAF-----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL 161
           RY K+HL+DA      +++ES    AG+EI  + E    ++GL  CYDLRFPE+  A  +
Sbjct: 131 RYRKIHLFDADIPDGPSLRESSGTVAGHEIG-VCETPLARLGLTVCYDLRFPEIYRALCV 189

Query: 162 -QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRII 215
            +GAE++V+P+A+        HW  LL ARA++  C++VAA + G  N      G + I+
Sbjct: 190 HEGAELVVVPSAFT-ARTGAAHWHVLLRARAIENQCFIVAAAQVGQHNERRNSYGHALIV 248

Query: 216 DPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           DP+G  +A   +   L +A++    + Q R ++P   +    PP+
Sbjct: 249 DPWGTILAEVEDGEGLAIADIDLALIEQTRQRMPCHQHAVLLPPE 293


>UniRef50_Q54JM9 Nitrilase homolog 2 n=1 Tax=Dictyostelium discoideum
           RepID=NIT2_DICDI
          Length = 328

 Score =  104 bits (260), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 65/256 (25%), Positives = 125/256 (48%), Gaps = 21/256 (8%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           E+N +     + +AA+N A L +LPE       +      K ++  +GE + +L   +KR
Sbjct: 67  EENVQNAIKHIDEAAKNGAKLISLPECF--NSPYSTSTFEKYSETEDGETVKKLSEAAKR 124

Query: 75  NMMTTI--LTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD-----AFAIQESRRVD 126
           N +  +      +    G+ +N   +    G +V ++ K+HL+D         +ES  + 
Sbjct: 125 NQIFLVGGSIPEIDKATGKIYNTCFIFNDKGEVVKKHRKIHLFDIDVPNKIRFKESETLT 184

Query: 127 AGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWS 184
            G+  + ++++   K+G+  CYD+RFPELA+  +  GA+ L+ P A+  V GP    HW 
Sbjct: 185 PGDSFS-VVDIGYCKIGVAICYDIRFPELAMLYSKMGAKFLIYPGAFNMVTGPA---HWE 240

Query: 185 TLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
            L   RA+D   ++ A     N +      G S I++ +G  +A   E  ++I +++   
Sbjct: 241 LLQRGRAVDNQVFVAAISPARNPSSTYQAWGHSTIVNSWGTILATTDEHQSIIYSDIDLN 300

Query: 240 RVRQVRAQLPVLNNRR 255
            + + R+ +P+ + +R
Sbjct: 301 TLNETRSSIPIYSQKR 316


>UniRef50_C8NJS3 Carbon-nitrogen hydrolase family protein n=16 Tax=Corynebacterium
           RepID=C8NJS3_COREF
          Length = 294

 Score =  104 bits (259), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 59/163 (36%), Positives = 89/163 (54%), Gaps = 9/163 (5%)

Query: 97  VALQAGNIVAR-YAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
            AL  GN +   Y K++ YDAF  +ES  V  GNE+  + +++G+KVG+  CYDLRFP  
Sbjct: 133 TALVTGNGLHEGYHKINTYDAFGYRESDTVKPGNELH-VFDLDGVKVGVAICYDLRFPTQ 191

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-------GNKN 208
               A  GAEI+V+P +W  G  K      L  ARALD+T +++   +        G   
Sbjct: 192 FQELARAGAEIIVVPTSWQDGEGKLEQLQVLTRARALDSTSWILMCDQARPTEKRKGPAG 251

Query: 209 IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVL 251
           IG S ++DP GV   +A   P  ++A++    ++ +R  +PVL
Sbjct: 252 IGHSMVVDPTGVIADSAGYEPETVIADIDLSNLQDIRKSIPVL 294


>UniRef50_A1SU00 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Psychromonas ingrahamii 37 RepID=A1SU00_PSYIN
          Length = 274

 Score =  104 bits (259), Expect = 3e-21,   Method: Compositional matrix adjust.
 Identities = 73/246 (29%), Positives = 114/246 (46%), Gaps = 14/246 (5%)

Query: 24  LMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEF---LGRLRRESKRNMMTTI 80
           L+A  +     L  LPE  L   D D  L++ S  L +G +   L  L +  +  ++   
Sbjct: 26  LLAALSPIPGQLVLLPENALCIADKDHYLAL-SENLGKGYYQSLLSALAKHYQCYLICGS 84

Query: 81  LTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVE-- 138
             I    T       LV    G +++ Y K+HL+DA            +   P  EV+  
Sbjct: 85  FPIKSTITDKIFTTCLVFSPLGELISHYHKMHLFDAQVADHKGIYKESDTFVPGQEVKLF 144

Query: 139 -------GMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARA 191
                   +KVGL  CYDLRFP L      QGA+IL++PAA+ +    + HW  LL ARA
Sbjct: 145 NWDCGAYSVKVGLTICYDLRFPGLFQTLRKQGADILLVPAAFTQTT-GQAHWLPLLQARA 203

Query: 192 LDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVL 251
           ++  CY++AA +  ++  G S II P+G  +   +E    I       ++ ++R  +P+L
Sbjct: 204 IENQCYIIAANQSSHETYGHSMIISPWGEVLEQLAEGEGSIHHLFEKSQIEKIRQAMPIL 263

Query: 252 NNRRFA 257
            + RF 
Sbjct: 264 EHNRFT 269


>UniRef50_Q0AX54 N-carbamoyl-D-amino acid amidohydrolase n=3 Tax=cellular organisms
           RepID=Q0AX54_SYNWW
          Length = 283

 Score =  103 bits (258), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 65/182 (35%), Positives = 98/182 (53%), Gaps = 17/182 (9%)

Query: 87  STPGRAWNM-LVALQAGNIVARYAKLHLYDA-----FAIQESRRVDAGNEIAPLLEVEGM 140
            + G+ +N   V  + G ++ R+ K HL+D       + +ES  ++AG  I  ++  +  
Sbjct: 90  DSQGKIYNSSFVFDERGELIGRHRKAHLFDIDIPGRISFRESDTLNAGENIT-IVHYKSR 148

Query: 141 KVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYM 198
              LM CYD RFPELA A AL+GAE+LV+PAA+    GP    HW  L+  RA+D   ++
Sbjct: 149 LFALMICYDCRFPELARAAALEGAELLVIPAAFNTTTGPA---HWKLLMRCRAVDNQLFV 205

Query: 199 VAAGECGNKNI-----GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN 253
           VAA    N +      G S ++DP+G  +  A     +I A +   R+ QVR +LP+L  
Sbjct: 206 VAASPARNPSASYQAWGHSLVVDPWGDILQEAGSGEEIIHARLDFSRLEQVRQELPLLRQ 265

Query: 254 RR 255
           RR
Sbjct: 266 RR 267


>UniRef50_A3ZLM3 Putative nitrilase n=1 Tax=Blastopirellula marina DSM 3645
           RepID=A3ZLM3_9PLAN
          Length = 258

 Score =  103 bits (258), Expect = 4e-21,   Method: Compositional matrix adjust.
 Identities = 79/256 (30%), Positives = 128/256 (50%), Gaps = 21/256 (8%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEAL--LARDDHDADLSVKSAQLLEGEFLGRLRRES 72
           E N +    L+AQAAE  A L  LPE    L R ++     V+ A+ + G    R+R+ +
Sbjct: 8   ELNLQTAERLIAQAAERGAQLVVLPELFNYLGRLEN----LVEHAETISGPTAVRMRKAA 63

Query: 73  KRNMMTTILTIHV--PSTPGRAWNM-LVALQAGNIVARYAKLHLYDA----FAIQESRRV 125
            ++ +  +         T  R +N  L+    G  +  Y K+HL+D       + ES  V
Sbjct: 64  LKHQIYLVAGSFAERSETESRVFNTSLIFDPLGKQIGVYRKIHLFDIDLPDVQVHESSFV 123

Query: 126 DAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWST 185
             G+E++ L +     V    CYDLRFPE+  +  L+    L LPAA+        HW  
Sbjct: 124 APGSEVS-LCQTALGGVAQAICYDLRFPEIVRSYDLEKVACLALPAAFT-AKTGAAHWQI 181

Query: 186 LLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIA-AASEMPALIMAEVTPE 239
           L+ +RA++   +++AA + G      ++ G S I+DP+G  +A A  +   +I AE++ E
Sbjct: 182 LVRSRAIENQLFLIAANQYGRYTNGIQSYGHSLIVDPWGTILAEAGGDAEEVITAEISLE 241

Query: 240 RVRQVRAQLPVLNNRR 255
           R+R+VR  +P L +RR
Sbjct: 242 RLREVRQHMPALRHRR 257


>UniRef50_Q3IFH8 Putative hydrolase, carbon-nitrogen family n=3 Tax=Alteromonadales
           RepID=Q3IFH8_PSEHT
          Length = 275

 Score =  103 bits (258), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 78/257 (30%), Positives = 129/257 (50%), Gaps = 21/257 (8%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESK- 73
           E+N +   + + Q       L  LPEA L       D ++K A+  E  +  +L    + 
Sbjct: 20  EQNIQTLVNQLQQLPTTRPLLVCLPEAFLVFSKSGND-TLKVAKQAE-RYKQQLSELCQL 77

Query: 74  RNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF------AIQESRRVD 126
            N+  +  T+  P    + +       A G +VA Y K+HL+D        + +ES    
Sbjct: 78  HNIWLSAGTMPEPYNDNKYYAASHLFNAQGELVASYNKMHLFDVTVDDSTASYRESDFTQ 137

Query: 127 AGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWS 184
           AGNE+  +++    K+GL  CYDLRF  L      QGAE++++P+A+  V G   + HW 
Sbjct: 138 AGNEVV-VVDSPFGKIGLTVCYDLRFSALYTQLVRQGAEVILVPSAFTVVTG---QAHWQ 193

Query: 185 TLLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
            LLAARA++T CY++AA      E G +  G S I+ P+G T++        I A +  +
Sbjct: 194 PLLAARAIETQCYVIAAAQYGAHENGRQTYGHSIILSPWGNTLSELPTGTGFISATLDLK 253

Query: 240 RVRQVRAQLPVLNNRRF 256
           ++ ++R  +PV +++RF
Sbjct: 254 QLHKIRRDMPVQSHQRF 270


>UniRef50_Q47VH0 Hydrolase, carbon-nitrogen family n=1 Tax=Colwellia psychrerythraea
           34H RepID=Q47VH0_COLP3
          Length = 273

 Score =  103 bits (258), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 77/250 (30%), Positives = 125/250 (50%), Gaps = 18/250 (7%)

Query: 16  KNAEICASLMAQAAENDASLFALPEALL---ARDDHDADLSVKSAQLLEGEF-LGRLRRE 71
           K AE+ + + A + E+   L  LPE  L   ++D    DL++ SA   +    LG L ++
Sbjct: 21  KIAELLSKITA-SQEDVQHLVVLPECCLYFGSKDSEQLDLAIASATGNDLCLALGELAKK 79

Query: 72  SKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYD------AFAIQESRRV 125
            K  ++   + I   S+     +  V    G ++ +Y K+HL+D        +  ESR  
Sbjct: 80  FKVYLVAGTIPILSTSSTKFTNSSCVFNPEGELIGQYDKIHLFDVNVSDSTKSYCESRYT 139

Query: 126 DAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWST 185
            AG EI+ ++  E   +GL  C+DLRFP L    ++ GA+I+ +P+A+ R   K  HW T
Sbjct: 140 QAGKEIS-MVNTEFANIGLSVCFDLRFPNLFQQLSIAGADIITVPSAFTRVTGKA-HWQT 197

Query: 186 LLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
           LL ARA++   Y+VAAG     E G +  G S II+P+G    +       I  +   E 
Sbjct: 198 LLQARAIENQVYIVAAGQEGVHENGRETWGHSMIINPWGEIEQSIETGEGYISIDYHSEE 257

Query: 241 VRQVRAQLPV 250
           + ++R  +P+
Sbjct: 258 LTRIRQSMPL 267


>UniRef50_Q9KE11 BH1047 protein n=2 Tax=Bacillaceae RepID=Q9KE11_BACHD
          Length = 271

 Score =  103 bits (257), Expect = 5e-21,   Method: Compositional matrix adjust.
 Identities = 77/250 (30%), Positives = 124/250 (49%), Gaps = 24/250 (9%)

Query: 16  KNAEICASLMAQAAENDASLFALPE-----ALLARDDHDADLSVKSAQLLEGEFLGRLRR 70
           K  E    +M Q  E+   L  LPE       L + +H A+   +  +L    FL  L R
Sbjct: 21  KVKEWIEDVMQQ--EDVPDLLVLPEMWTTAYTLDQLEHLAEGEERYTEL----FLKELAR 74

Query: 71  ESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYDAFAIQESRRVDAGN 129
           E   N++   +        G+ +N  LV  + G+ V +Y K+HL    +  E   +  G+
Sbjct: 75  EHNVNIVAGSIA---KKEKGKLYNRALVFDRRGHTVYQYDKIHLVPMLS--EPDYLTGGD 129

Query: 130 EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAA 189
             A + E+EG K+GL+ CYDLRFPEL  + AL+GAEI+ + A W     +  HW  L  A
Sbjct: 130 AAASVFELEGTKMGLVICYDLRFPELMRSLALEGAEIVFIVAEWPEA--RAVHWEVLQRA 187

Query: 190 RALDTTCYMVAAGECGN----KNIGQSRIIDPFG-VTIAAASEMPALIMAEVTPERVRQV 244
           RA++   Y+++    G        G+S +IDP+G V I  + +    +  ++ P++V +V
Sbjct: 188 RAIENQSYVISCNRVGAYAGVTFAGRSMVIDPWGDVLIQGSRDQEQTLTTKLNPDKVSEV 247

Query: 245 RAQLPVLNNR 254
           R  +P+  +R
Sbjct: 248 REAVPIFQSR 257


>UniRef50_Q6BU62 DEHA2C13310p n=6 Tax=Saccharomycetales RepID=Q6BU62_DEBHA
          Length = 312

 Score =  103 bits (257), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 86/303 (28%), Positives = 137/303 (45%), Gaps = 55/303 (18%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA GQ   +S    NA I   L+ +A    A +  LPEA     D+ A  +++S QL + 
Sbjct: 7   VACGQLCSSSNLSSNANIVKKLIRKAVTAKAKVLFLPEAT----DYIAKDAIQSMQLAQS 62

Query: 63  ---EFLGRLRRESKR------NMMTTILTIHVPSTPGR----------AWNMLVALQAGN 103
              +F+  ++RE K       + +   + +H PS+             + N L     G 
Sbjct: 63  SHEKFISDIQRELKEVYADNGDGLFVAVGVHEPSSSTGVNAKEILNKVSNNQLWIGNRGE 122

Query: 104 IVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMK-----VGLMTCYDLRFP 153
           I+ RY KLHL+D        ++ES  V+ G+ +     +         +G  TCYD+RFP
Sbjct: 123 ILHRYQKLHLFDINIENGPILKESNSVEPGSSVLKPFPINTSSLSEFLIGFATCYDIRFP 182

Query: 154 ELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI---- 209
           EL L     GA I+  P+A+      + HW  L  ARA+DT CY+V A +CG  +     
Sbjct: 183 ELGLRLRSLGANIITYPSAFTT-KTGQAHWELLARARAVDTQCYVVMAAQCGEHDTGGDK 241

Query: 210 -----GQSRIIDPFGVTIA------------AASEMPALIMAEVTPERVRQVRAQLPVLN 252
                G S IIDP+G  I+            +  +   + +A++  + V + R  +P++ 
Sbjct: 242 KRISYGNSIIIDPWGNKISECHKYNEDLVVDSEGDYYEMCVADLDLDMVEKTRRDMPLMT 301

Query: 253 NRR 255
           +RR
Sbjct: 302 HRR 304


>UniRef50_A0BR54 Chromosome undetermined scaffold_122, whole genome shotgun sequence
           n=2 Tax=Oligohymenophorea RepID=A0BR54_PARTE
          Length = 281

 Score =  103 bits (257), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 63/187 (33%), Positives = 92/187 (49%), Gaps = 20/187 (10%)

Query: 85  VPSTPG-RAWNMLVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVE 138
           +P   G + +N       G ++  Y K HL+D         +ES    AG+    +++ E
Sbjct: 89  IPEKSGDKMYNTAFCFNNGQLLVTYRKTHLFDIDIPGKITYKESLTFSAGDNY-KIVDTE 147

Query: 139 GMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTC 196
             K G+  CYD+RFPELA     +G   LV P ++    GPL   HW  LL ARA+D  C
Sbjct: 148 YGKFGIGICYDIRFPELAQIMREKGCHFLVYPGSFNLTTGPL---HWELLLKARAVDYQC 204

Query: 197 YMV---AAGECGN-----KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQL 248
           Y+    +A   GN     K  G S ++DP    +A     P++I++EV  + + QVR Q+
Sbjct: 205 YVAGVSSARYMGNDESIYKAWGHSTLLDPMAKVLATCEHDPSVIISEVDLDYLEQVRQQI 264

Query: 249 PVLNNRR 255
           PV   RR
Sbjct: 265 PVSQQRR 271


>UniRef50_C6N396 Nitrilase n=2 Tax=Legionella RepID=C6N396_9GAMM
          Length = 286

 Score =  103 bits (256), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 82/273 (30%), Positives = 133/273 (48%), Gaps = 32/273 (11%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q   ++   +N +    LM QA E+DA L  LPE       H+ D      +L  G
Sbjct: 18  VALAQMVSSANVVENLQQVEKLMIQAREDDAQLVLLPENFAFMGRHETD------KLHIG 71

Query: 63  EFLGRLRRESKRNMMTTILTIHV---------PSTPGRAWNMLVALQAGNIVARYAKLHL 113
           E  G+   + K + +   L + V           +  RA + LV  + G   ARY K+HL
Sbjct: 72  EVYGQGPIQEKISQLAKQLGLWVVAGTMPLKGSGSKVRA-SCLVYDEQGLCAARYDKIHL 130

Query: 114 YDAF-----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
           +D       A  ES  ++ G+++  +++    K+GL  CYDLRFPEL     +QGA++  
Sbjct: 131 FDVSVSPQEAYCESATIERGHDLV-VVDTPVGKIGLTVCYDLRFPELYQQLLIQGAQLFT 189

Query: 169 LPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVT 221
           +P+A+  V G     HW  LL ARA++   Y++AA      E G    G S II+P+G  
Sbjct: 190 VPSAFTAVTGLA---HWEVLLRARAIENLSYVLAANQGGHHENGRSTYGHSMIIEPWGAV 246

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
           +A  ++   ++ AE+  + ++ +R   P +++ 
Sbjct: 247 LAQQADGIGVVTAEIDLQGLQHLRKTFPSVDHH 279


>UniRef50_Q9NQR4 Omega-amidase NIT2 n=88 Tax=Eukaryota RepID=NIT2_HUMAN
          Length = 276

 Score =  103 bits (256), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 69/262 (26%), Positives = 122/262 (46%), Gaps = 19/262 (7%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLG 66
           Q  ++S+   N     S + +AA   A + +LPE       + A    + A+ + GE   
Sbjct: 10  QLQISSIKSDNVTRACSFIREAATQGAKIVSLPECF--NSPYGAKYFPEYAEKIPGESTQ 67

Query: 67  RLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-----AFAIQ 120
           +L   +K   +  I         G+ +N        G ++A+Y K+HL+D         Q
Sbjct: 68  KLSEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVPGKITFQ 127

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPL 178
           ES+ +  G+  +   +    +VGL  CYD+RF ELA   A +G ++LV P A+    GP 
Sbjct: 128 ESKTLSPGDSFS-TFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPA 186

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAASEMPALIM 233
              HW  L  +RA+D   Y+  A    +        G S +++P+G  +A A    A++ 
Sbjct: 187 ---HWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEEAIVY 243

Query: 234 AEVTPERVRQVRAQLPVLNNRR 255
           +++  +++ ++R Q+PV   +R
Sbjct: 244 SDIDLKKLAEIRQQIPVFRQKR 265


>UniRef50_C0VX65 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Corynebacterium glucuronolyticum
           RepID=C0VX65_9CORY
          Length = 257

 Score =  103 bits (256), Expect = 8e-21,   Method: Compositional matrix adjust.
 Identities = 54/152 (35%), Positives = 78/152 (51%), Gaps = 8/152 (5%)

Query: 108 YAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           Y K HLYDAF   ES  V  G  +    + EG+  G+  C+D+RFP L    A  GA+ +
Sbjct: 105 YDKTHLYDAFGFAESDTVAPGENVV-TFDWEGITFGVAICFDIRFPALFKKMARAGAQAI 163

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAA-------GECGNKNIGQSRIIDPFGV 220
           ++P +W  G  K +HW  L  ARALD+  +++A        G      +G S +IDP G 
Sbjct: 164 IVPTSWTPGEQKVYHWRLLSRARALDSATFILATDQAFLDDGRTDPVGVGYSSVIDPLGQ 223

Query: 221 TIAAASEMPALIMAEVTPERVRQVRAQLPVLN 252
            +A   +   ++ AE+    V +VR  LPVL 
Sbjct: 224 VVAELEQDEGILYAELDTTAVEKVRQSLPVLG 255


>UniRef50_A8RJL1 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RJL1_9CLOT
          Length = 254

 Score =  102 bits (255), Expect = 9e-21,   Method: Compositional matrix adjust.
 Identities = 80/265 (30%), Positives = 127/265 (47%), Gaps = 25/265 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE----ALLARDDHDADLSVKS 56
           M VA  QFAV     K  +I              L  LPE       A +++      K 
Sbjct: 1   MKVAIVQFAVNDEESKEQKIIRMEGILDNLKGTDLIVLPELWNIGFFAYEEY-----AKQ 55

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVAL-QAGNIVARYAKLHLY 114
           ++LL G     L R++K  + + I T  +    G + +N    + + G ++  Y K+HL+
Sbjct: 56  SELLTGPTFSSLARKAK-ELGSYIFTGSISEQDGDKCYNTAGLIDREGRLLGTYRKMHLF 114

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
            A    E + ++ G++   +++ E  K+G+  CYD+RFPEL   +   GAEILV  A W 
Sbjct: 115 AA----ERQYMERGDKPV-VIDTEFGKIGMSICYDIRFPELFRKEVEMGAEILVNCAGW- 168

Query: 175 RGPL-KEHHWSTLLAARALDTTCYMV----AAGECGNKNIGQSRIIDPFGVTIAAASEMP 229
             P  +   W+ L   RA++  CYM+    A    GN  IG+S +IDP+G   AAA  M 
Sbjct: 169 --PYPRVESWNMLHPVRAMENQCYMLSCCCAGASRGNPFIGRSMVIDPWGTVQAAAGNME 226

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNR 254
            ++ +E+ PE++  +R     L +R
Sbjct: 227 TVVKSEIFPEQLAGIRETFTALKDR 251


>UniRef50_Q0VS65 Carbon-nitrogen hydrolase family protein n=2 Tax=Alcanivorax
           RepID=Q0VS65_ALCBS
          Length = 285

 Score =  102 bits (255), Expect = 9e-21,   Method: Compositional matrix adjust.
 Identities = 86/277 (31%), Positives = 126/277 (45%), Gaps = 33/277 (11%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q       + N E  A L+ +A +  ASL  LPE       +  D    +A   E 
Sbjct: 10  VAAIQMTSVESAKANLEQAAQLLQEAHDQGASLAVLPENFAG---YGVDYRALAA---EY 63

Query: 63  EFLGRLRRESKRNMMTTILTIHVPS----------TPGRAWNMLVALQAGNIVARYAKLH 112
           E L +   E    +   I+   +PS           P      L     G +V RY KLH
Sbjct: 64  ERLEQWLCEQASRLGMAIIGGSIPSLTRPDGEPVPAPRVRTRSLAVSSEGQVVGRYDKLH 123

Query: 113 LYDA------FAIQESRRVDAGNEI--APLLEVEGMKVGLMTCYDLRFPELALAQALQGA 164
           L+DA         +ES   + G  I  APL    G++VGL  CYDLRFP LA      GA
Sbjct: 124 LFDAQVHDAQGQYRESDFFEPGEAIVTAPL---GGVQVGLAICYDLRFPALAQRLTSAGA 180

Query: 165 EILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFG 219
           E+LV P+A+     K  HW  LL A A+ T CY++ A +CG       + G S ++ P+G
Sbjct: 181 ELLVYPSAFTAVTGKA-HWELLLRATAVQTGCYVLGANQCGQHSPRRASYGHSMLVSPWG 239

Query: 220 VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             +A+    P +++  +    + ++R ++PV  ++R 
Sbjct: 240 DVVASLGNAPGVLVTPLDLATLYELRQRMPVQQHQRL 276


>UniRef50_B2SXB2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=15 Tax=Proteobacteria RepID=B2SXB2_BURPP
          Length = 283

 Score =  102 bits (255), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 84/265 (31%), Positives = 119/265 (44%), Gaps = 18/265 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q   T   E+N      L+A+AA   A L  LPE        D D         +G
Sbjct: 21  VAALQMVSTPDRERNLAEAGRLIAEAAAEGAQLVLLPEYFCFMGFKDTDKLAVREPYQDG 80

Query: 63  ---EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
               FL    R  +  ++   L +  P         LV    GN VARY K+HL++    
Sbjct: 81  PIQRFLADAARRHQVWVIGGTLPLMSPEAARVLNTTLVFDPQGNEVARYDKIHLFNFEKG 140

Query: 120 QESRRVDAGNEIAPLLEVEGM-----KVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           +ES   D    I P  EV        +VGL  CYDLRFPEL   + +    ++V+P+A+ 
Sbjct: 141 EES--FDEARTICPGGEVRTFEAPFGRVGLSVCYDLRFPELY--RRMGDCALVVVPSAFT 196

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTIAAASEMP 229
               + H W  LL ARA++  CY++AA      E G +  G S +IDP+G  +A   E  
Sbjct: 197 YTTGRAH-WEMLLRARAVENQCYVLAAAQGGKHENGRRTWGHSMLIDPWGEIVAVRDEGA 255

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNR 254
            ++   +   R+ +VR  LP   +R
Sbjct: 256 GVVAGNLERARIDEVRQSLPAWRHR 280


>UniRef50_D2RS34 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RS34_9EURY
          Length = 277

 Score =  102 bits (255), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 79/263 (30%), Positives = 130/263 (49%), Gaps = 30/263 (11%)

Query: 15  EKNAEICASLMAQAAENDASLFALPE----ALLARDDHDADLSVKSAQLLEGEFLGRLRR 70
           ++N E     +++AAE  A L ALPE       A D ++     + A+ LEGE L RLR 
Sbjct: 24  DENVERALEAISRAAERGADLVALPELFNVGYFAFDSYN-----RLAEPLEGETLTRLRE 78

Query: 71  ESKRNMMTTIL-----------TIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
            +  + +  +            T   P+  G A    +    G +   Y K HL+  +  
Sbjct: 79  AAADHEIAVLAGSIVEDLAATETADTPAEEGLANTAALFDADGGLQLVYRKHHLF-GYQS 137

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            ES  +  G  I     V G+ VG  TCYDLRFPEL       GAE++++P+AW    ++
Sbjct: 138 AESELLVPGERIETAT-VAGVPVGATTCYDLRFPELYRRLIDAGAELVLVPSAWPYPRIE 196

Query: 180 EHHWSTLLAARALDTTCYMV---AAGECGNKN---IGQSRIIDPFGVTIAAASEMPALIM 233
             HW TL  ARA++   ++     +G   +++   +G+S + DP+G T+A++ + P L++
Sbjct: 197 --HWETLSRARAIENQAFVATINGSGRFPDEDATLLGRSTVYDPWGTTLASSGDDPTLVV 254

Query: 234 AEVTPERVRQVRAQLPVLNNRRF 256
           A++    V ++R + P L +RR 
Sbjct: 255 ADLDLGAVDRIREEFPALRDRRL 277


>UniRef50_D0RND5 Hydrolase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RND5_9RICK
          Length = 265

 Score =  102 bits (255), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 65/248 (26%), Positives = 122/248 (49%), Gaps = 13/248 (5%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           ++N +    L  QA ++ A +   PE        +  L  KS    +G  +  + + +K 
Sbjct: 17  KENLDQVIKLSDQAVKDGAQIILTPENTFLLTLDEGVLKEKSEDYEKGFCINEIVKYAKS 76

Query: 75  NMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYD-----AFAIQESRRVDAG 128
           N +  ++           +N  V +   G IV  Y K+H++D       + +ES++  AG
Sbjct: 77  NSIWFLIGGTPVKENNNIFNRSVLISPKGEIVTTYDKIHMFDVNLPNGESYEESKKFKAG 136

Query: 129 NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLA 188
             ++ + ++    +GL  CYDLRFP        +GA+ L +P+A+ +    E HW  LL 
Sbjct: 137 ESLS-VTKLPWGNLGLSICYDLRFPNHYRQLMKKGADFLAVPSAFTKN-TGERHWHILLR 194

Query: 189 ARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQ 243
           +RA++  CY++A  + G      +  G S I+ P GV ++   E   LI++E+  E+V++
Sbjct: 195 SRAIENFCYVLAPAQTGKHFNNRETYGHSMIVSPDGVVLSEKKEDIGLIISEIDIEKVKK 254

Query: 244 VRAQLPVL 251
           +R+++P +
Sbjct: 255 IRSEIPSI 262


>UniRef50_Q15ZG7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Alteromonadales RepID=Q15ZG7_PSEA6
          Length = 276

 Score =  102 bits (254), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 79/269 (29%), Positives = 124/269 (46%), Gaps = 24/269 (8%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLG 66
           Q   T    +N       +AQ   N+ +L  LPE        D  L   +  L +G    
Sbjct: 8   QMTSTPDVTENLHFVEQQLAQLTVNEPTLVVLPECFACFGGGDKALLSIAESLGDGPIQA 67

Query: 67  RLRRESKRNMMTTILTIHVPSTPGRAWN-------MLVALQAGNIVARYAKLHLYDAFAI 119
           RL   +K+  +  +      S P ++ N        L+   AG  V  Y K+HL+D    
Sbjct: 68  RLMGMAKQYGVWLV----AGSMPLKSENPDKFTASCLLINDAGERVTEYQKIHLFDVQVA 123

Query: 120 Q------ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA-EILVLPAA 172
                  ES+   AG+ +  + +     +GL  CYD+RFP L  A A   A +++ LPAA
Sbjct: 124 DNTKTYCESKYTQAGSTLVSVPDTPFGHLGLAICYDVRFPGLFQAMAEHKALDVIALPAA 183

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASE 227
           + +    E HW  LL+ARA++  CY+VAAG+ G      +  G S II P+G T+A   +
Sbjct: 184 FTQ-KTGEAHWQALLSARAIENQCYLVAAGQTGVHANQRQTHGHSCIISPWGETLAELPQ 242

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
              +I A++ P  + ++R  +PV  + +F
Sbjct: 243 SVGVINAQLEPAILNRIRRDMPVYAHNKF 271


>UniRef50_A4XQL4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=33 Tax=Proteobacteria RepID=A4XQL4_PSEMY
          Length = 286

 Score =  102 bits (253), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 79/259 (30%), Positives = 121/259 (46%), Gaps = 20/259 (7%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           + N  +   ++ +AA+  A L  LPE   A    D      +    EG  L  L+ ++ R
Sbjct: 19  QSNLRLARRMLERAAQGGARLVVLPENFAAMGRRDLTAIGHAEAAGEGPILPWLK-QAAR 77

Query: 75  NMMTTILTIHVPSTP-----GR--AWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDA 127
           ++   I+   +P  P     GR  A ++L+  Q G  VARY KLHL+D        R   
Sbjct: 78  DLSLWIVAGTLPLPPDDEPQGRPHACSLLIDEQ-GERVARYDKLHLFDVDVTDNRGRYRE 136

Query: 128 GNEIAP-----LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
            ++        + +    ++GL  CYDLRFPEL  A    GAE++ +PAA+        H
Sbjct: 137 SDDFVHGQRLVVADTPVGRLGLTVCYDLRFPELFGALREAGAELISVPAAFT-AVTGAAH 195

Query: 183 WSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPALIMAEVT 237
           W  L  ARA++T CY++AAG+ G         G S IIDP+G  +    +    ++A   
Sbjct: 196 WQVLTRARAIETQCYILAAGQGGEHPGQRLTFGHSAIIDPWGTVLVEQDQGEGALLAARD 255

Query: 238 PERVRQVRAQLPVLNNRRF 256
                 +R ++PV  +RRF
Sbjct: 256 AAEQAAIRQRMPVQQHRRF 274


>UniRef50_C8VW38 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Clostridia RepID=C8VW38_DESAS
          Length = 285

 Score =  102 bits (253), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 79/272 (29%), Positives = 128/272 (47%), Gaps = 26/272 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA--DLSVKSAQLL 60
            A  Q  V+     N     S++ +A    A L  +PE      ++ +  D +       
Sbjct: 5   TAVCQMLVSHSKSDNISKAKSMIEEAVSQGAELIIMPEMFNCPYENTSFPDFAESYPDGE 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRA-WNMLVALQ-AGNIVARYAKLHLYD--- 115
             +FL +  +E+K  ++   +     +  GR  +N        G ++ R+ K+HL+D   
Sbjct: 65  TVKFLAQTAKENKIYLVGGSVPESAETESGRQIFNTSFFFDPQGQLIVRHRKVHLFDIDI 124

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMK---VGLMTCYDLRFPELALAQALQGAEILVLP 170
               + +ES  +  G++I     V G K   +GL  CYD+RFPEL  A  L+GA+++++P
Sbjct: 125 EGGISFRESDTLGRGDQIT----VAGTKWCDIGLAICYDMRFPELMRAMVLKGAKMILIP 180

Query: 171 AAW--VRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTIA 223
           AA+    GP    HW   L  RA+D   +++AA      E      G S I+DP+G  +A
Sbjct: 181 AAFNTTTGPA---HWEITLKTRAVDNQTFVIAASPARNLEAAYHAYGHSLIVDPWGEILA 237

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            A     +I A +  E V +VR QLP+L +RR
Sbjct: 238 EAGTGEEIIYASIDLELVDRVRRQLPLLRHRR 269


>UniRef50_Q1AWK1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Bacteria RepID=Q1AWK1_RUBXD
          Length = 276

 Score =  101 bits (252), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 86/265 (32%), Positives = 135/265 (50%), Gaps = 18/265 (6%)

Query: 4   AAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG- 62
           AA Q + T    +N  +  +L+ +AA   A+L ALPE  L       ++  ++A+ + G 
Sbjct: 9   AAIQMSSTPDRGENRRVAEALIREAAAAGATLVALPE--LWSCHGLEEVYRENAEPIPGP 66

Query: 63  --EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
             EFLG L RE    ++   +   V  +        +    G++VA Y K+HL+D   + 
Sbjct: 67  TTEFLGSLARELGIYLLGGSILERVSGSERLGNTSTLYAPDGSLVAVYRKVHLFD-VEVS 125

Query: 121 ESRRVDAGNEIAPLLEVEGMK-----VGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
             R +++ N IAP  E    K     VGL  CYD+RFPEL    AL+GAE+L +PAA+  
Sbjct: 126 GRRYLESAN-IAPGGEAVAAKAGPVTVGLSVCYDVRFPELYRLLALRGAEVLAVPAAFTL 184

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPA 230
              K+ HW  LL ARA++   Y++A  + G K       G+S I+DP+G  ++   +   
Sbjct: 185 QTGKD-HWELLLRARAVENQAYVLAPAQWGRKADGRWTYGRSMIVDPWGTVLSTCPDRDG 243

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRR 255
             +A +    + ++RA+ P L NRR
Sbjct: 244 YALATLDLGYLERLRAEFPSLANRR 268


>UniRef50_A4SSL0 Beta-ureidopropionase n=2 Tax=Gammaproteobacteria
           RepID=A4SSL0_AERS4
          Length = 277

 Score =  101 bits (252), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 81/269 (30%), Positives = 120/269 (44%), Gaps = 15/269 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +AA Q      W+ N E  A+ +A        L  LPE      +    L   + ++ 
Sbjct: 1   MWLAAIQLVSGRHWQDNREQIAAELAALPAGRPLLVLLPENFALFGERQGYLD-GAERIG 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAW---NMLVALQAGNIVARYAKLHLYDAF 117
           EG    +L   +K   +  +      + PG A    + LV   AG +   Y K+HL+D  
Sbjct: 60  EGPIQQQLAAWAKEYGIWLVAGAMPTAIPGSAHIHTSSLVFDPAGELKGHYHKIHLFDVD 119

Query: 118 AIQESRRVDAGNEIAP-----LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                 R       +P     L++     +GL  CYDLRFPEL    A  GA +L++PAA
Sbjct: 120 VADNQGRYRESETFSPGQDCVLIDSPFGPLGLSICYDLRFPELYRQLARAGARVLLVPAA 179

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTIAAASE 227
           +      E HW  LL ARA++  CY+VAA      E G    G S +IDP+G  +A    
Sbjct: 180 FT-AVTGEAHWEPLLRARAIENQCYVVAANQGGTHETGRHTWGHSMVIDPWGRVLACQPS 238

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             A ++A + PE   +++  +PVL + R 
Sbjct: 239 GRATVLAAMDPELGDELKRTMPVLQHARL 267


>UniRef50_B7Q2J6 Carbon-nitrogen hydrolase, putative n=1 Tax=Ixodes scapularis
           RepID=B7Q2J6_IXOSC
          Length = 399

 Score =  101 bits (252), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 64/214 (29%), Positives = 116/214 (54%), Gaps = 16/214 (7%)

Query: 57  AQLLEGEFLGRLRRESKR-NMMTTILTIHVPSTP--GRAWNMLVALQA-GNIVARYAKLH 112
           A+ L+G  +   +  +KR ++  ++ ++H+       +  N  V + + GNIV  Y+K+H
Sbjct: 22  AEPLDGPLIAEYKSLAKRLSVWLSLGSVHIKDADQGNKVSNTHVVINSEGNIVDTYSKVH 81

Query: 113 LYDAFA----IQESRRVDAGNEIAPLLEVEGMKVGL--MTCYDLRFPELALAQALQGAEI 166
           ++D       I+ES    AG  I   +     KVGL  ++ +  +FPE +L+ A  GA+I
Sbjct: 82  MFDVDVPGARIRESDYTAAGTRITRPVATPVGKVGLGIISFHVGKFPEFSLSLAKMGADI 141

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVT 221
           +  P+A+   P    HW  ++ ARA+++ CY+V+A + G  N      G + ++DP+G  
Sbjct: 142 ITYPSAFTV-PTGMAHWEVIMRARAIESQCYVVSAAQVGQHNPKRSSYGHALVVDPWGCV 200

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           +A  S+   + +AE+  + V +VR  +PV N+RR
Sbjct: 201 VAQCSDAVGIAVAEINLDSVAKVRQAIPVWNHRR 234


>UniRef50_A1RVM3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Thermoproteaceae RepID=A1RVM3_PYRIL
          Length = 269

 Score =  101 bits (252), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 57/168 (33%), Positives = 92/168 (54%), Gaps = 5/168 (2%)

Query: 91  RAWNMLVALQ-AGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYD 149
           + +N  V +   G +V  Y K HL+DA+  +ES  V+ G E++ +  V G +V    C++
Sbjct: 84  KVYNTTVLVDPGGRVVGLYRKTHLFDAYGYKESEFVEPGAELSQVYTVRGARVAFAVCFE 143

Query: 150 LRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI 209
           LRFPE+    AL GA+++ +PAAW  GPLKE     L  ARA++   Y+  +   G +  
Sbjct: 144 LRFPEVFRELALAGADLVAVPAAWYAGPLKEEILHILARARAIENGMYIAVSALWGPRFT 203

Query: 210 GQSRIIDPFGVTIA--AASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G+S +++PFGV  A   A E    ++ ++    V + R  +P +  RR
Sbjct: 204 GRSVVVNPFGVVEAELGAGERYREVLIDL--RLVEEARKTVPTIYLRR 249


>UniRef50_C5RGI3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RGI3_CLOCL
          Length = 265

 Score =  101 bits (252), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 67/251 (26%), Positives = 119/251 (47%), Gaps = 17/251 (6%)

Query: 13  VWE---KNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLR 69
           VWE   KN   C  L+ +A + +  L   PE  L     + +   +  ++ +        
Sbjct: 11  VWEDKSKNKINCIELINEAKDQNVDLLVFPEMTLTGFSMNIE---EIGEIFDKSTTIDFF 67

Query: 70  RESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAG 128
           R+   +    I   +V      A N  + + A G I++ Y K+H + ++   E++   +G
Sbjct: 68  RKQAISKSINIGFGYVEKKQNTALNKFIIISAQGQIISNYTKIHPF-SYG-NETKHYSSG 125

Query: 129 NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLA 188
            EI    EV G+ +  + CYDLRFPE+  A + + + I+V+ A W +  ++  HW TLL 
Sbjct: 126 EEIQHC-EVNGIIISPLICYDLRFPEIFQACSYKSSLIIVI-ANWPKSRIE--HWRTLLK 181

Query: 189 ARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQV 244
           ARA++  CY+      G+ +     G S II+P+G  I        L++ ++  E V+  
Sbjct: 182 ARAIENQCYIAGVNRVGSGDNLLYNGNSMIINPYGEVITEKINDQGLVIGDINVENVKDY 241

Query: 245 RAQLPVLNNRR 255
           R +  + N+R+
Sbjct: 242 RIKFNIKNDRK 252


>UniRef50_B4D6H9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D6H9_9BACT
          Length = 260

 Score =  101 bits (252), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 80/249 (32%), Positives = 118/249 (47%), Gaps = 16/249 (6%)

Query: 13  VWEK---NAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLR 69
           VWE    N     +L+  AA    SL  LPE        +  ++ + A+  +  F+  L 
Sbjct: 14  VWEDKAANFRKVEALVDAAAPAPGSLVVLPEMFSCGFSMNLAVTRQGAEREDEAFIAALA 73

Query: 70  RESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGN 129
           R+    +   +++       GR  + +V    G +VARY K+H +      ES+  +AG+
Sbjct: 74  RKHGVFITGGVVSRGAGEM-GRN-DAVVFSPEGKLVARYTKIHPFSGGG--ESQGHEAGS 129

Query: 130 EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK-EHHWSTLLA 188
           EI    E  G  V    CYDLRFPE+  A A +GA + V+ A W   P+K + HW TLL 
Sbjct: 130 EIV-TFEWGGFVVAPFVCYDLRFPEIFRAAARKGANLFVVMALW---PVKRQQHWLTLLQ 185

Query: 189 ARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQV 244
           ARA++   Y V     G +      G+S ++DP GV IA A E   ++ A + PE V   
Sbjct: 186 ARAIENQAYAVGVNRVGREPELLYAGRSVVVDPHGVIIADAGEREHILPATLEPEVVHSW 245

Query: 245 RAQLPVLNN 253
           R   P L +
Sbjct: 246 RRDFPALRD 254


>UniRef50_B4RQA3 Nitrilase n=28 Tax=Neisseriaceae RepID=B4RQA3_NEIG2
          Length = 281

 Score =  101 bits (251), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 18/265 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q       E N      L+A+AAE  A    LPE  +    +D      +  L  G
Sbjct: 17  VAAVQMVSGVSPETNVAAMKRLVARAAEQGADWVLLPEYWVLMGANDTGKLALAEPLGGG 76

Query: 63  EFLGRLRRESKRNMMTTILTIHVP-STP--GRAWNMLVALQAGNI-VARYAKLHLYDAFA 118
            F   L  E+ +     +    VP  +P  G+  N L+      +    Y K+HL+    
Sbjct: 77  RFQTALS-ETAKECGVVLFGGTVPLQSPEAGKVMNTLLVYGCDGVRTGLYHKMHLFGFSG 135

Query: 119 IQE----SRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           + E    +  + AG E+ P L  EGM V    CYD+RFPE    Q     ++L+LPAA+ 
Sbjct: 136 LGERYAEADTIRAGREV-PHLSAEGMPVAAGICYDVRFPEFFRRQLP--FDVLMLPAAFT 192

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTIAAASEMP 229
               K H W  LL ARA++  CY+VAA      E G +  G S I+DP+G  +    E  
Sbjct: 193 HTTGKAH-WELLLRARAVENQCYVVAAAQGGLHENGRRTFGHSMIVDPWGDVLDVLPEGE 251

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNR 254
            ++ A++   R+  VR +LP L +R
Sbjct: 252 GIVTADIDANRLNSVRNRLPALKHR 276


>UniRef50_A7GE66 Hydrolase, carbon-nitrogen family n=24 Tax=cellular organisms
           RepID=A7GE66_CLOBL
          Length = 278

 Score =  100 bits (250), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 65/208 (31%), Positives = 110/208 (52%), Gaps = 19/208 (9%)

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNM-LVALQAGNIVARYAKLHLYD---- 115
           GE +  +++ +K ++   I+   +P   G + +N  +V    G ++A++ K+HL+D    
Sbjct: 67  GETVKAIKKAAK-DLELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDIDVK 125

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW- 173
                +ES  + AGN+I  L      K+G+M CYD+RFPEL+   A++GA+I+  PAA+ 
Sbjct: 126 GGVTFKESDTLTAGNKIT-LFNTPWGKLGVMICYDIRFPELSRIMAVKGAKIIFTPAAFN 184

Query: 174 -VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
              GP    HW TL  +RALD   YMV      ++N      G S I  P+G  +A    
Sbjct: 185 MTTGPA---HWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLDA 241

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
              ++ +E+  +   ++R +LP+L + R
Sbjct: 242 KEDILFSEIDLDYESKIREELPLLKHIR 269


>UniRef50_A0L7H1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L7H1_MAGSM
          Length = 275

 Score =  100 bits (250), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 74/247 (29%), Positives = 124/247 (50%), Gaps = 21/247 (8%)

Query: 24  LMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTIL 81
           L+ +AA   A L  LPE  +    D+ +     +  Q   G  L  ++  ++R+    ++
Sbjct: 30  LLEEAATAGAKLLVLPENFSFFGADEKEKLAHQEDPQ--HGPSLRMVQAFAQRHG-AWVV 86

Query: 82  TIHVPSTPGRAWNM----LVALQAGNIVARYAKLHLYDAF-----AIQESRRVDAGNEIA 132
              +P+  G +  +     V    G +VARY K+HL+D         +ES  + AG++  
Sbjct: 87  AGSIPTDVGESQRVANSSFVVNDQGQVVARYDKIHLFDVTLNGGEGYRESDMIRAGSQPV 146

Query: 133 PLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARAL 192
            +++    ++GL  CYDLRFPEL  A    GAEI  +PAA+      + HW  LL ARA+
Sbjct: 147 -VVDSPFGRIGLSICYDLRFPELYRALTDAGAEIFTVPAAFTL-TTGQVHWELLLRARAV 204

Query: 193 DTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQ 247
           +  C+++A  + G      K  G S I++P+G  +A  ++     +A + P RV + R+Q
Sbjct: 205 ENFCHLLAPNQWGRHPGNRKTYGSSMIVEPWGSVVARVADGEGYALAPLDPARVARCRSQ 264

Query: 248 LPVLNNR 254
           +P L +R
Sbjct: 265 IPCLQHR 271


>UniRef50_A6F4Z1 Predicted amidohydrolase n=2 Tax=Marinobacter RepID=A6F4Z1_9ALTE
          Length = 286

 Score =  100 bits (249), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 56/168 (33%), Positives = 93/168 (55%), Gaps = 17/168 (10%)

Query: 102 GNIVARYAKLHLYDAFA------IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
           G  VARY K+HL+DA         +ES   + G ++  +++    ++G+  CYDLRFPEL
Sbjct: 123 GREVARYDKIHLFDATVEDAQGQYRESDTFEPGEDVV-VIDTPAGRLGMAICYDLRFPEL 181

Query: 156 ALAQALQGAEILVLPAA--WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KN 208
                 Q AE + LP+A  W  G   + HW  L+ ARA++   ++VAA + G      + 
Sbjct: 182 FRQLREQDAEWVSLPSAFTWYTG---DAHWHALIRARAIENQVWLVAAAQGGQNSERRRT 238

Query: 209 IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            G S I+DP+G  ++   E P ++++E+  E ++ +R ++PV  +RR 
Sbjct: 239 YGHSAIVDPWGRILSEIDEGPGIVVSELDRETLKDIRTRMPVWEHRRL 286


>UniRef50_Q94JV5 AT4g08790/T32A17_100 n=10 Tax=Viridiplantae RepID=Q94JV5_ARATH
          Length = 307

 Score =  100 bits (248), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 82/271 (30%), Positives = 131/271 (48%), Gaps = 26/271 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q    +    N   C+ L+ +AA   A L   PE      D + + SVK A+ L+G
Sbjct: 39  VAAAQMTSVNDLMTNFATCSRLVQEAALAGAKLICFPENFSFVGDKEGE-SVKIAEPLDG 97

Query: 63  EFLGR---LRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYD--- 115
             + R   L R+S  N+  ++             N  V +  AG I   Y K+HL+D   
Sbjct: 98  PVMERYCSLARDS--NIWLSLGGFQERFDDTHLCNTHVVIDDAGMIRDTYQKMHLFDVDV 155

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL---QGAEILVLP 170
               + +ES     G +I  +    G ++GL  CYDLRFP++   Q L   Q A++L++P
Sbjct: 156 PGGSSYKESSFTVPGTKIVSVDSPVG-RLGLTVCYDLRFPKIY--QQLRFEQKAQVLLVP 212

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA 225
           +A+ +    E HW  LL ARA++T CY++AA + G  N      G + IIDP+G  +   
Sbjct: 213 SAFTK-VTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDTLIIDPWGTVVGRL 271

Query: 226 SE--MPALIMAEVTPERVRQVRAQLPVLNNR 254
            +     +++A++    +  VR ++P+   R
Sbjct: 272 PDRVSTGIVVADIDFSLIDSVRTKMPIDKQR 302


>UniRef50_C4R2Y9 Nit protein n=1 Tax=Pichia pastoris GS115 RepID=C4R2Y9_PICPG
          Length = 297

 Score =  100 bits (248), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 67/209 (32%), Positives = 102/209 (48%), Gaps = 31/209 (14%)

Query: 77  MTTILTIHVPSTP--GRAWNMLVALQA-GNIVARYAKLHLYD-----AFAIQESRRVDAG 128
           +   + +H P+    GR  N L+ L + G+I  RY KLHL+D       +++ES  V  G
Sbjct: 83  LCVCVGVHEPANDARGRVKNTLLWLNSHGDIAQRYQKLHLFDVALEDGRSLRESDSVQPG 142

Query: 129 NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLA 188
             + P       KVGL  CYD+RFPEL+L     GA++L  P+A+        HW  L  
Sbjct: 143 ANLIPPFNSPVGKVGLAICYDIRFPELSLRLRALGAQLLAFPSAFTM-RTGAAHWELLGR 201

Query: 189 ARALDTTCYMVAAGECGNKNIGQS------------------RIIDPFGVTIAAASEM-- 228
           ARA+DT CY+V A + G    G+S                   I+DP+G  +A  S++  
Sbjct: 202 ARAVDTQCYVVMAAQAGRHGTGESVGLTGEAPALPRESYGHAMIVDPWGSILAQCSDVGR 261

Query: 229 --PALIMAEVTPERVRQVRAQLPVLNNRR 255
               + +A++  +R+  VR  +P+   RR
Sbjct: 262 GTEDICIADIDLDRLDTVRRDMPLWEQRR 290


>UniRef50_Q12ZA5 Carbon-nitrogen hydrolase family protein n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12ZA5_METBU
          Length = 270

 Score = 99.8 bits (247), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 60/192 (31%), Positives = 98/192 (51%), Gaps = 14/192 (7%)

Query: 72  SKRN---MMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAG 128
           SK+N   ++ +I+  H         N+   L+ G +V  Y K H +     +E     +G
Sbjct: 80  SKKNKCIIVGSIIEKHSSKNRETYTNLGFCLEDGELVGTYTKTHPFG----KEKEYFTSG 135

Query: 129 NEIAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLL 187
           + I P+ L+   + VGL  CY++RFPE+A    L GA+IL+  A +     +EH W TL 
Sbjct: 136 DVIEPIHLKERDLTVGLQICYEMRFPEIARKLCLSGADILMTIAEFPNP--REHQWRTLA 193

Query: 188 AARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQ 243
            ARA++   + +A    G+       G S IIDP G  IA A +   +I+ E+    +++
Sbjct: 194 TARAIENQVFHIACNRSGSDPTSTFFGGSMIIDPLGNVIADAKDGECVIIEEIDTSIMKK 253

Query: 244 VRAQLPVLNNRR 255
            R ++PV ++RR
Sbjct: 254 TRKEIPVFDDRR 265


>UniRef50_A5N8H1 Predicted hydrolase n=3 Tax=Clostridium RepID=A5N8H1_CLOK5
          Length = 275

 Score = 99.8 bits (247), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 67/246 (27%), Positives = 116/246 (47%), Gaps = 20/246 (8%)

Query: 25  MAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIH 84
           + +AA     + ALPE      +             +GE L  L   +K  M   I+   
Sbjct: 26  IYKAANKGTDIVALPEMFNCYYNTKYFREYAEKDDCKGETLSMLSSAAKE-MGIYIVGGS 84

Query: 85  VP--STPGRAWNM-LVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLE 136
           +P     G  +N   V  + G ++ ++ K+HL+D         +ES  +  G+++  +++
Sbjct: 85  IPEIDDKGNIYNTSFVFNEKGELIGKHRKMHLFDIDIKDKITFKESNVLTPGDKVT-VID 143

Query: 137 VEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDT 194
            +  K+G+  CYD+RFPEL    ALQGA+I+ +PA++    GP    HW  L  + A++ 
Sbjct: 144 TKWGKIGVAICYDVRFPELMRLMALQGAKIIFIPASFNTTTGP---SHWELLFRSAAVEN 200

Query: 195 TCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLP 249
             Y V      N N      G S ++DP+G  +    E   ++++E+  E + +VR  +P
Sbjct: 201 QLYTVGISPARNINYSYVAYGNSLVVDPWGKILNILDEKEGILLSEIDLEYIYEVRKSIP 260

Query: 250 VLNNRR 255
           V  +RR
Sbjct: 261 VFEHRR 266


>UniRef50_A0LQU6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Acidothermus cellulolyticus 11B
           RepID=A0LQU6_ACIC1
          Length = 272

 Score = 99.8 bits (247), Expect = 9e-20,   Method: Compositional matrix adjust.
 Identities = 80/258 (31%), Positives = 120/258 (46%), Gaps = 22/258 (8%)

Query: 14  WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESK 73
           W    +    L+A     DA L  LPE L       +    + A  L G  + RL   +K
Sbjct: 16  WPDRVDRVVDLVASC--RDADLVVLPE-LWVPGAFASRFFAEVATELPGPIIPRLGAVAK 72

Query: 74  R----NMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAG 128
                 M  T +    P+T    +N  V L   G I   Y K+HL+  F   E+R + AG
Sbjct: 73  ELGAFIMAGTFIERADPATDRIGYNTAVLLNPDGAIAHTYRKVHLF-GFHEGEARMLAAG 131

Query: 129 NEIAPLLEVEGMKV------GLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
           N++     +EG ++      G  TCYDLRFPEL      QG ++LV+P+ W    L+  H
Sbjct: 132 NDVT-TCRLEGGRMTETATYGTSTCYDLRFPELYRILVDQGCDLLVIPSGWPAQRLE--H 188

Query: 183 WSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           W  L  ARA++   ++VA  E G++      G S ++DP+G  +A A     ++  ++  
Sbjct: 189 WRVLTRARAIENQLFVVACNETGHQQGVELAGHSVVVDPWGQVVAEAGAGEEILTVDIDL 248

Query: 239 ERVRQVRAQLPVLNNRRF 256
             V ++R   PVL +RRF
Sbjct: 249 GEVPRIRRDFPVLPDRRF 266


>UniRef50_C9KQR5 Hydrolase, carbon-nitrogen family n=1 Tax=Mitsuokella multacida DSM
           20544 RepID=C9KQR5_9FIRM
          Length = 259

 Score = 99.4 bits (246), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 61/172 (35%), Positives = 87/172 (50%), Gaps = 11/172 (6%)

Query: 90  GRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCY 148
           G+ +N      + G  VA Y K HL+      ES+   AG E+     ++G++ G+  CY
Sbjct: 89  GKVYNTCYVFDRTGTEVASYDKTHLFSPSG--ESKDFAAGREMV-TFRLDGVRCGVAVCY 145

Query: 149 DLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC---- 204
           D+RFPE     AL+   +L LPAAW    L   HW  L  ARA++   Y++AA E     
Sbjct: 146 DVRFPEFIRKLALEDIAVLFLPAAWPASRLS--HWQILTRARAIENQFYVIAANEAGTDE 203

Query: 205 -GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            GN   G S I+DP+G  I  A E  A++ A + P   R +R  + V  +RR
Sbjct: 204 QGNHLAGHSAILDPWGEAIVEAGESEAILTARLRPGLRRHIRETINVFADRR 255


>UniRef50_Q9LE50 Nitrilase 1 like protein n=2 Tax=Viridiplantae RepID=Q9LE50_ARATH
          Length = 316

 Score = 99.4 bits (246), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 81/267 (30%), Positives = 130/267 (48%), Gaps = 26/267 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q    +    N   C+ L+ +AA   A L   PE      D + + SVK A+ L+G
Sbjct: 39  VAAAQMTSVNDLMTNFATCSRLVQEAALAGAKLICFPENFSFVGDKEGE-SVKIAEPLDG 97

Query: 63  EFLGR---LRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYD--- 115
             + R   L R+S  N+  ++             N  V +  AG I   Y K+HL+D   
Sbjct: 98  PVMERYCSLARDS--NIWLSLGGFQERFDDTHLCNTHVVIDDAGMIRDTYQKMHLFDVDV 155

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL---QGAEILVLP 170
               + +ES     G +I  +    G ++GL  CYDLRFP++   Q L   Q A++L++P
Sbjct: 156 PGGSSYKESSFTVPGTKIVSVDSPVG-RLGLTVCYDLRFPKIY--QQLRFEQKAQVLLVP 212

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA 225
           +A+ +    E HW  LL ARA++T CY++AA + G  N      G + IIDP+G  +   
Sbjct: 213 SAFTK-VTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDTLIIDPWGTVVGRL 271

Query: 226 SE--MPALIMAEVTPERVRQVRAQLPV 250
            +     +++A++    +  VR ++P+
Sbjct: 272 PDRVSTGIVVADIDFSLIDSVRTKMPI 298


>UniRef50_A8Q4Q4 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8Q4Q4_MALGO
          Length = 174

 Score = 99.4 bits (246), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 57/125 (45%), Positives = 75/125 (60%), Gaps = 11/125 (8%)

Query: 102 GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G I ARY K+HLYD       +I ES     G E+ P +     + GL+TCYD+RFPE+A
Sbjct: 41  GQIQARYRKMHLYDVQVQHGMSICESNTTIPGTELVPPVSTPFGRTGLLTCYDMRFPEVA 100

Query: 157 LAQALQGAEILVLPAAW-VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRII 215
           L+    GA+IL  P+A+ VR      HWSTLL ARA+DT C++VAA + G  + G +R  
Sbjct: 101 LSLRRSGAQILTFPSAFAVR--TGAAHWSTLLQARAIDTQCWVVAAAQVGT-HPGTTRTS 157

Query: 216 D--PF 218
           D  PF
Sbjct: 158 DMPPF 162


>UniRef50_Q65KK0 Methylthioribose recycling protein n=1 Tax=Bacillus licheniformis
           ATCC 14580 RepID=Q65KK0_BACLD
          Length = 259

 Score = 99.0 bits (245), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 62/194 (31%), Positives = 98/194 (50%), Gaps = 12/194 (6%)

Query: 68  LRRESKRNMMTTIL-TIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVD 126
           L+  +K N +  +  ++ V    G    M +A + G+++  Y+K HL+    + E   + 
Sbjct: 68  LQETAKANRIHIVCGSVAVKKKSGVYNIMYIADKNGHLIKEYSKAHLFQL--MDEHLYLS 125

Query: 127 AGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL-KEHHWST 185
           AG+      E+EGM      CYD+RFPE       +GA I+ + A W   PL +  HW +
Sbjct: 126 AGSGDGRF-ELEGMPAAGFICYDIRFPEWIRKHTSEGAGIIFVSAEW---PLARLDHWQS 181

Query: 186 LLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERV 241
           LL ARA++  C++ A    G    N+  G S +IDP G T+A A    A+I AE+    +
Sbjct: 182 LLKARAIENQCFVAACNRSGKDPANEFAGHSTVIDPLGRTLAEAGRGEAVIRAEIDLRDI 241

Query: 242 RQVRAQLPVLNNRR 255
            + R Q+PV  + R
Sbjct: 242 EKARGQIPVFEDIR 255


>UniRef50_O31664 UPF0012 hydrolase mtnU n=96 Tax=Bacilli RepID=MTNU_BACSU
          Length = 259

 Score = 99.0 bits (245), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 71/245 (28%), Positives = 115/245 (46%), Gaps = 24/245 (9%)

Query: 22  ASLMAQAAENDASLFALPEAL-----LARDDHDADLSVKSAQLLEGEFLGRLRRESKRNM 76
           A    +     A +  LPE       LA  D  AD   +SAQ         L++ +K++ 
Sbjct: 24  AEFFIEKESKHADVLVLPELWTTGYDLANLDELADEDGRSAQ-------SWLKKTAKKHG 76

Query: 77  MTTIL-TIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLL 135
           +  +  ++ V         M +A + G I+  Y K HL+    + E   + AG+E     
Sbjct: 77  VHIVAGSVAVRKNSDVYNTMYIADKEGQIIKEYRKAHLFQL--MDEHLYLSAGSEDG-YF 133

Query: 136 EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL-KEHHWSTLLAARALDT 194
           E++G+K   + CYD+RFPE       +GA +L + A W   PL +  HW +LL ARA++ 
Sbjct: 134 ELDGVKSSGLICYDIRFPEWIRKHTTKGANVLFISAEW---PLPRLDHWKSLLIARAIEN 190

Query: 195 TCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPV 250
            C++ A    G    N+  G S IIDP+G  +A       ++ AE+  +   +VR  +PV
Sbjct: 191 QCFVAACNCTGSNPDNEFAGHSLIIDPWGRVLAEGGREEGIVRAEIDLQESAEVRESIPV 250

Query: 251 LNNRR 255
            ++ R
Sbjct: 251 FDDIR 255


>UniRef50_B7G2G6 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7G2G6_PHATR
          Length = 308

 Score = 98.2 bits (243), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 83/296 (28%), Positives = 138/296 (46%), Gaps = 45/296 (15%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALL------ARDDHDADLSVKS 56
           +A  Q   TS    N    A     A  + A++  LPE         ++   +AD  ++ 
Sbjct: 15  IAVAQLRSTSDKFSNLLDVARCAGWAKRDGAAMLFLPECCCFLGESASQTLEEADPPIQD 74

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTIHVPSTP---------GRAWNM-LVALQAGNIVA 106
           A +L  + L  + RES   +  +   IHV   P          R +N  L+    G +  
Sbjct: 75  ADILILDGLRNIARES--GLWISAGGIHVSGAPPHDTADPDHSRVYNTHLIIDCVGTVKC 132

Query: 107 RYAKLHLYDA-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL 161
            Y K+HL+D       +++ES     G  +       G  +G+  CYDLRFPE+ +    
Sbjct: 133 LYRKIHLFDVEIPGQVSLRESATTAPGKAVKVCDSPIGC-LGVTICYDLRFPEMYVKLTT 191

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIID 216
           QGA+IL++P+A+   P    HW TLL ARA++  C+++AA + G  N      G + I+D
Sbjct: 192 QGAQILLVPSAFTI-PTGTAHWHTLLRARAIENQCFVIAAAQFGEHNHKRESYGHALIVD 250

Query: 217 PFG--------------VTIAAASEM-PALIMAEVTPERVRQVRAQLPVLNNRRFA 257
           P+G              V+I A++ + P++++ E+  + V   R ++P+ N+RR A
Sbjct: 251 PWGEVLADAGGADGGGTVSIDASNLVTPSIMVQEIDLDLVTSARQRIPIQNHRRAA 306


>UniRef50_Q0S9Y1 Possible nitrilase n=3 Tax=Actinomycetales RepID=Q0S9Y1_RHOSR
          Length = 270

 Score = 98.2 bits (243), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 54/157 (34%), Positives = 85/157 (54%), Gaps = 8/157 (5%)

Query: 102 GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL 161
           G I   Y+K+H++  +   E++ +  G +I       G  +   TCYDLRFP L      
Sbjct: 104 GQIHHHYSKVHVF-GYDSLEAQLLQPGTQIHTTDTPFG-PIAATTCYDLRFPGLWTELVA 161

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDP 217
            GA+++++PAAW +   ++ HW  L +ARA+D   +++A    G  N     G SRI+DP
Sbjct: 162 AGAQLVIVPAAWPKA--RKEHWRLLTSARAVDNQVFVIACNATGTHNSVELGGHSRIVDP 219

Query: 218 FGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
           +G  IA A     + +AE+ P  V + RA+ PVL +R
Sbjct: 220 WGTVIAEADSSEGITIAEIDPAVVDRTRAEFPVLRDR 256


>UniRef50_A3WPW5 Predicted amidohydrolase, nitrilase family protien n=2
           Tax=Idiomarina RepID=A3WPW5_9GAMM
          Length = 279

 Score = 98.2 bits (243), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 58/167 (34%), Positives = 91/167 (54%), Gaps = 13/167 (7%)

Query: 102 GNIVARYAKLHLYDAFA------IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
           G  +ARY K+HL+D          +ESR   AG+ I   +++    VG+  CYDLRFPEL
Sbjct: 106 GRCLARYDKIHLFDVDVADNTRQYRESRWTRAGSSIV-TIDLGFAVVGMAVCYDLRFPEL 164

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIG 210
             A   +GA+I++LP+A+        HW  L+ ARA++   YM+A  + G      +  G
Sbjct: 165 FKALRAKGADIILLPSAFTE-VTGAAHWHPLVRARAIEQQVYMLAPNQYGEAANGRRTYG 223

Query: 211 QSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
            S I+DP+G  +A  ++   ++ A    E++  +RAQ+PV +  R A
Sbjct: 224 HSMIVDPWGEVVAEQADGEGVVSAYFDREKLENIRAQMPVADQTRLA 270


>UniRef50_A9UWV2 Predicted protein (Fragment) n=1 Tax=Monosiga brevicollis
           RepID=A9UWV2_MONBE
          Length = 270

 Score = 97.4 bits (241), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 53/172 (30%), Positives = 94/172 (54%), Gaps = 12/172 (6%)

Query: 102 GNIVARYAKLHLYDAFA----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELAL 157
           G + + Y K+HL+D        +ES     G  +  + +     +GL  CYD+RFPE+  
Sbjct: 90  GQVRSTYDKIHLFDVDTADGVFKESDFTQPGRTLVTVPDTPLGTLGLSICYDVRFPEVYT 149

Query: 158 AQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN------KNIGQ 211
               +GA++L++P+A++    K  HW  LL ARA++T C+++AA + G       ++ G 
Sbjct: 150 ELRARGADVLLVPSAFMPSTGKA-HWEALLRARAIETQCFVIAAAQAGTHAPSTRRSYGH 208

Query: 212 SRIIDPFG-VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           S ++DP+G V +   +E   L+   +  ER+ +VR ++P+ N+R+  P  L 
Sbjct: 209 SLVVDPWGDVLVDGDAENEGLLAVTIDLERITEVRTKMPLANHRQAVPRHLF 260


>UniRef50_Q7QKM8 AGAP012662-PA (Fragment) n=14 Tax=Neoptera RepID=Q7QKM8_ANOGA
          Length = 308

 Score = 97.4 bits (241), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 76/265 (28%), Positives = 124/265 (46%), Gaps = 15/265 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           +A  Q  V    EKN +    L+  A  E DA++  LPE   A    D  L+V + ++  
Sbjct: 36  IALIQLRVVDSKEKNLKNAIDLIRIAKKEKDANVVVLPECFNAPYTADTLLNV-AEEIPT 94

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDA---- 116
           GE    L   ++   +  +    V S  GR +N        G++VA Y K+HL D+    
Sbjct: 95  GETCRALSNAARDFGVHVVGGSIVESCSGRLYNTCTVWGPEGDLVATYRKVHLCDSSLSG 154

Query: 117 -FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
              + E++   AG++ A    V   ++GL  C+D+RF E A A    G ++L+ PA    
Sbjct: 155 KMTVAETKLFTAGSKYATF-TVGETRIGLGICWDMRFAEFATAYRTMGCDLLIYPAV-CD 212

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPA 230
            P  E HW  L  ARALD   ++       + +      G S ++DP+G  I  A+E   
Sbjct: 213 VPTGEQHWELLAKARALDNQAFVAFCSPARDTHAKLIPYGHSLVVDPWGRIIQRATEFQE 272

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRR 255
           +++A++  + +  VR ++PV   +R
Sbjct: 273 IVVADLVLKELTDVRKRIPVFEQKR 297


>UniRef50_B9JB81 Amidohydrolase protein n=4 Tax=cellular organisms
           RepID=B9JB81_AGRRK
          Length = 285

 Score = 97.4 bits (241), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 58/165 (35%), Positives = 95/165 (57%), Gaps = 13/165 (7%)

Query: 102 GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G +++RY K+H++D       + +ES     G+E A ++ +   ++G   CYD+RFP+L 
Sbjct: 106 GKLISRYDKIHMFDVDLDNGESWRESAVYRPGSE-ARIVSLPFAELGFSICYDVRFPQLF 164

Query: 157 LAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQ 211
            AQA+ GA+++ +PAA+ R    E HW  LL ARA++   +++AA      E G +  G 
Sbjct: 165 RAQAVAGAQVMTVPAAFTR-QTGEAHWEILLRARAIENGMFVIAAAQAGKHEDGRETFGH 223

Query: 212 SRIIDPFGVTIAAASEM-PALIMAEVTPERVRQVRAQLPVLNNRR 255
           S IIDP+G  +AAA     A+++AE+    V+    ++P L N R
Sbjct: 224 SMIIDPWGKVLAAAGGTGEAVLVAEIDVAAVKSAHDKIPNLKNAR 268


>UniRef50_C7ICC9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Clostridium papyrosolvens DSM 2782
           RepID=C7ICC9_9CLOT
          Length = 267

 Score = 97.1 bits (240), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 73/258 (28%), Positives = 123/258 (47%), Gaps = 20/258 (7%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG-EFL 65
           Q  V+   + N E   S++ + ++  A +  LPE  +    +D  L    A+ +E  + L
Sbjct: 11  QMTVSDKKKDNLEKALSMLEECSKQGADIAILPEMFIC--PYDTKLFPLYAENVENSKTL 68

Query: 66  GRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD-----AFAI 119
             + + +K N M  +      S  G  +N  V   + GN +A++ K+HL+D       + 
Sbjct: 69  SVISKSAKYNNMYIVAGTIPESNNGFIYNSSVMFDRQGNTIAKHRKVHLFDINVKDGISF 128

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGP 177
           +ES  + AG  +  + E E   +GL  C+D+RF  L      +GA+I++ PA++    GP
Sbjct: 129 RESDVLTAGRSVT-VAETEFGCIGLAICFDMRFAGLYSEMTEKGAKIIITPASFNMTTGP 187

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPALI 232
               HW  L+ ARALD   + VA       +      G S + DP+G  I+ A E   ++
Sbjct: 188 A---HWELLVRARALDNQVFHVAVSSARETSANYVSYGNSMVCDPWGSVISRAEEKEDIL 244

Query: 233 MAEVTPERVRQVRAQLPV 250
           +A++    V  VR Q+PV
Sbjct: 245 IADIDLNMVNSVRNQIPV 262


>UniRef50_B4IMX5 GM23937 n=3 Tax=Drosophila sechellia RepID=B4IMX5_DROSE
          Length = 243

 Score = 96.7 bits (239), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 16/168 (9%)

Query: 101 AGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
            G++VA++ K+HL+D         +ES  + AGN+   ++ V+G K+G+  CYD+RF E+
Sbjct: 70  TGDLVAKHRKMHLFDIDVKGGIRFKESETMSAGNDFT-IINVDGHKIGIGICYDIRFEEM 128

Query: 156 ALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----- 208
           A      G E+++ PAA+    GPL   HW  L  +RA D   ++V      + +     
Sbjct: 129 ARLYRNAGCELIIYPAAFNMTTGPL---HWELLQRSRANDNQLFVVTTSPARDTSAEYVA 185

Query: 209 IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            G S +++P+     +ASE    ++A++    V QVR Q+PV   RR 
Sbjct: 186 YGHSMVVNPWAKVQQSASEGEETLVADIDFSEVEQVRQQIPVFGQRRL 233


>UniRef50_Q28TG7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Jannaschia sp. CCS1 RepID=Q28TG7_JANSC
          Length = 298

 Score = 96.7 bits (239), Expect = 7e-19,   Method: Compositional matrix adjust.
 Identities = 80/242 (33%), Positives = 117/242 (48%), Gaps = 31/242 (12%)

Query: 35  LFALPEA--LLARDDHDADLSVKSAQLLEG--EFLGRLRRESKRNMMTTILTIHVPSTP- 89
           + ALPEA  L+ RD   A   +      EG   ++   R E+ R+     + +H  S P 
Sbjct: 39  MLALPEAAGLMDRDKDHARAQITG----EGGDPYITACREEAARHG----IWVHSGSCPV 90

Query: 90  ----GRAWNMLVALQ-AGNIVARYAKLHLYDAF-----AIQESRRVDAGNEIAPLLEVEG 139
               GR  N  V +  +G+IVARY K+HL+D F     A  ES R   G+E A + +   
Sbjct: 91  KAPDGRYLNHTVLVAPSGDIVARYDKIHLFDVFLDGRRATGESDRYAPGSE-AVVADTPF 149

Query: 140 MKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMV 199
             + L  CYDLRFP L    AL G+ ++ +P+A+   P    HW  LL ARA++   Y++
Sbjct: 150 GPMALSICYDLRFPHLYRDYALAGSTVMFIPSAFTV-PTGRAHWEVLLRARAIENGAYVI 208

Query: 200 AAGECGNK-----NIGQSRIIDPFGVTIAA-ASEMPALIMAEVTPERVRQVRAQLPVLNN 253
           AA + G+        G S I+ P+G  +A    + P  I  ++    V   R Q+P L N
Sbjct: 209 AAAQVGHHADGRVTWGHSLIVSPWGDVLADLGGDAPGQITLDLPLGDVVAARRQIPNLQN 268

Query: 254 RR 255
            R
Sbjct: 269 AR 270


>UniRef50_C6JLR5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Fusobacterium varium ATCC 27725
           RepID=C6JLR5_FUSVA
          Length = 274

 Score = 96.3 bits (238), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 57/174 (32%), Positives = 93/174 (53%), Gaps = 10/174 (5%)

Query: 87  STPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLM 145
           S  G+  N    + + G I+A Y+K+HLY    + E+  +++GN+ A ++E E  K G M
Sbjct: 94  SKDGKIRNTTFLINRNGEIIADYSKMHLYSD--MDENFMIESGNK-AEVVETEIGKFGFM 150

Query: 146 TCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG 205
            CYD+RF EL+   AL+GAE +++ + +    +  +HW TLL ARA++   +++A    G
Sbjct: 151 ICYDIRFCELSRIYALKGAEAIIVTSDFPNPRV--NHWRTLLQARAIENQMFVIACNRVG 208

Query: 206 NKNI----GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
              +    G S IIDP+G  IA   E   +I   V    +  +R  + V  +R 
Sbjct: 209 ESPMGSYCGHSLIIDPWGEIIAEGGEKEEIIHGSVDLSVIHNIRETIHVFRDRH 262


>UniRef50_Q8RUF8 AT5g12040/F14F18_210 n=16 Tax=Eukaryota RepID=Q8RUF8_ARATH
          Length = 369

 Score = 96.3 bits (238), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 80/267 (29%), Positives = 123/267 (46%), Gaps = 24/267 (8%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG---- 62
           Q +VTS  ++N       + +AA   A L  LPE   +   +D+   V + ++  G    
Sbjct: 94  QLSVTSDKKRNISHAKKAIEEAASKGAKLVLLPEIWNSPYSNDS-FPVYAEEIDAGGDAS 152

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVALQA-GNIVARYAKLHLYD----- 115
                L   SKR +  TI+   +P   G R +N      + G + A++ K+HL+D     
Sbjct: 153 PSTAMLSEVSKR-LKITIIGGSIPERVGDRLYNTCCVFGSDGELKAKHRKIHLFDIDIPG 211

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW-- 173
                ES+ + AG E   +++ +  ++G+  CYD+RF ELA+  A +GA +L  P A+  
Sbjct: 212 KITFMESKTLTAG-ETPTIVDTDVGRIGIGICYDIRFQELAMIYAARGAHLLCYPGAFNM 270

Query: 174 VRGPLKEHHWSTLLAARALDT-----TCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEM 228
             GPL   HW  L  ARA D      TC        G    G S ++ PFG  +A     
Sbjct: 271 TTGPL---HWELLQRARATDNQLYVATCSPARDSGAGYTAWGHSTLVGPFGEVLATTEHE 327

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRR 255
            A+I+AE+    + Q R  LP+   RR
Sbjct: 328 EAIIIAEIDYSILEQRRTSLPLNRQRR 354


>UniRef50_Q0F1V1 Hydrolase, carbon-nitrogen family protein n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0F1V1_9PROT
          Length = 272

 Score = 96.3 bits (238), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 57/165 (34%), Positives = 87/165 (52%), Gaps = 11/165 (6%)

Query: 102 GNIVARYAKLHLYD----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELAL 157
           G + A Y K+HL+D      +  ES  V AG     +  +   + GL  CYD+RFPEL  
Sbjct: 109 GRMRAIYDKIHLFDVDLDGESYHESESVVAGEHPCSV-ALGDFRFGLSICYDIRFPELYR 167

Query: 158 AQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQS 212
             A  G +++ + AA+        HW TLL ARA++  CY++A+ + G      +  G S
Sbjct: 168 HYADSGCDVVCVVAAFTE-QTGHAHWQTLLRARAIENQCYLLASAQWGVHADGRRTWGHS 226

Query: 213 RIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
            IIDP+G  +A   E   +IMA++T  R+  +R  LP L +R+ +
Sbjct: 227 MIIDPWGEVMALQEESTGVIMADLTSARLAHIRKILPSLQHRQIS 271


>UniRef50_C1SGV5 Predicted amidohydrolase n=1 Tax=Denitrovibrio acetiphilus DSM
           12809 RepID=C1SGV5_9BACT
          Length = 260

 Score = 96.3 bits (238), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 59/236 (25%), Positives = 116/236 (49%), Gaps = 18/236 (7%)

Query: 25  MAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIH 84
           MA+ A++   +F LPE      D+    ++++      E +  +  +S  N  T ++T H
Sbjct: 26  MAEHADDKDVIFMLPEMWGCGFDYK---NLQNFAEHTYELISEI--QSIINSDTLVITTH 80

Query: 85  VPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGL 144
             +   + +N + A+    ++ +Y K  L+      E    D G++I  +++ +G++VG 
Sbjct: 81  PETNQNKVFNTVYAVTKTAVIGKYRKNFLFSPTG--EDNYFDKGDDIC-VVDFKGVRVGF 137

Query: 145 MTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC 204
           + CY++RFPE+    A  GA+++ +PA W     K+ HW TL  ARA++   Y++    C
Sbjct: 138 LLCYEIRFPEMFRLTASAGADVVAIPAVWPEA--KKDHWQTLTKARAVENQMYVIGCN-C 194

Query: 205 G-------NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN 253
                   + + G S   DP+G  +  +     ++  E+  E V  +R ++P L++
Sbjct: 195 SVMHTKKKDMDCGYSVAYDPWGSNLYESVSGEHVLTCEINRENVNDIRQKIPSLSD 250


>UniRef50_C0GEE7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GEE7_9FIRM
          Length = 261

 Score = 95.9 bits (237), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 49/157 (31%), Positives = 84/157 (53%), Gaps = 8/157 (5%)

Query: 102 GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL 161
           G ++++Y K+HL+  +  +ES+ +  G     +++ +    G+ TCYDLRFPEL    A 
Sbjct: 106 GKLISKYRKIHLF-GYKSEESKLLTRGT-TPTVIKTDLGTFGISTCYDLRFPELYRKMAD 163

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDP 217
            GA+  ++ +AW    L+  HW+     RAL+  CY+++    G    N   G S ++DP
Sbjct: 164 LGAQAFLVTSAWPLARLE--HWTLFNRTRALENQCYLISCNCSGQIKENPFAGNSMMVDP 221

Query: 218 FGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
           +G  + +A E PAL+   +    V ++R   P  N+R
Sbjct: 222 WGTVLHSAGEEPALLHGSIDLSHVSEIRDSFPAFNDR 258


>UniRef50_B6K212 UPF0012 hydrolase n=1 Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6K212_SCHJY
          Length = 334

 Score = 95.5 bits (236), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 69/248 (27%), Positives = 120/248 (48%), Gaps = 25/248 (10%)

Query: 27  QAAENDASLFALPEAL-----LARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTIL 81
           +AA+N A++  LPE       +A     A+  V ++     + L ++ +++K  +    +
Sbjct: 75  EAAKNGANIVVLPEIFNSPYSVAHFREYAEDFVTTSHSPSYDALSQMAKDAKVYLFGGSI 134

Query: 82  TIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLL 135
              V     + +N  LV    G+++ ++ K+HL+D          ES  +  GN +  ++
Sbjct: 135 ---VELDNDKVYNTALVFSPDGSLLGKHRKMHLFDVDIPNGIRFIESEVLSPGNAMT-MV 190

Query: 136 EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALD 193
           + E  K G+  CYD+RFPELA+  A  G   ++ P+A+    GPL   HW  L  +RA+D
Sbjct: 191 QTEFGKFGMGICYDIRFPELAMIAARNGCAGMIYPSAFNTTTGPL---HWELLARSRAVD 247

Query: 194 TTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQL 248
              ++       N +      G S  +DP+G  +A A E PA+I A++ P  +   R  +
Sbjct: 248 NQIFVALCSPARNMDASYHAYGHSMAVDPYGKILAEAQEGPAIIYADINPTTMEVCRRAI 307

Query: 249 PVLNNRRF 256
           P+   RRF
Sbjct: 308 PLYTQRRF 315


>UniRef50_A8PU96 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8PU96_MALGO
          Length = 330

 Score = 95.5 bits (236), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 59/179 (32%), Positives = 89/179 (49%), Gaps = 16/179 (8%)

Query: 90  GRAWNMLVALQA-GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVG 143
           GR +N    L A G +++ + KLHL+D         QES  + AG+ +  + + +  +  
Sbjct: 147 GRLYNTSCVLDAQGRLISLHRKLHLFDIDIPGKMTFQESLTLTAGDRLT-IFDCDLGRFA 205

Query: 144 LMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAA 201
           L  CYDLRFPE A   +  GA  ++ P A+    GP+    W  LL ARA+D   Y +  
Sbjct: 206 LGICYDLRFPESAQIASRLGASTILYPGAFNTTTGPVA---WELLLRARAIDNQVYTIGC 262

Query: 202 GEC----GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
                  G    G S ++DP G  I+   E   ++ A + PER+ +VR  +PV + RRF
Sbjct: 263 SPARPPAGYPAWGHSTVVDPLGQVISTCDEKETVVYATLHPERIAEVRKTVPVSSQRRF 321


>UniRef50_A3SP65 Possible nitrilase n=2 Tax=Rhodobacteraceae RepID=A3SP65_9RHOB
          Length = 284

 Score = 95.5 bits (236), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 61/164 (37%), Positives = 88/164 (53%), Gaps = 12/164 (7%)

Query: 102 GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G+IV RY K+HL+D       + +ES  V  G + A + +    ++G   CYDLRFP L 
Sbjct: 109 GSIVGRYDKIHLFDVDLGPGQSYRESATVAPGGQ-AVIHDTPKARIGHAICYDLRFPALF 167

Query: 157 LAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQ 211
              A +GAEIL  PAA+ +    E HW  L  ARA++TT +MV+A        G +  G 
Sbjct: 168 HTLACEGAEILCCPAAFTK-LTGEAHWHILNRARAIETTRFMVSACATGPVPGGGETYGH 226

Query: 212 SRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           S IIDP+G  +A       +I A +  + V   ++++P LNN R
Sbjct: 227 SLIIDPWGRVLADGGSDKGIISATIDLDMVAATQSRIPSLNNAR 270


>UniRef50_Q5WM18 Methylthioribose recycling protein n=3 Tax=Bacillales
           RepID=Q5WM18_BACSK
          Length = 275

 Score = 95.5 bits (236), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 63/199 (31%), Positives = 105/199 (52%), Gaps = 15/199 (7%)

Query: 64  FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQES 122
           FL +L R  + +M+   +        G  +N  + + A G +V  Y K+HL     + E 
Sbjct: 80  FLQQLARAHRIHMVAGSIAT---KKDGGIYNTALVIDAQGKLVYTYDKVHLVPM--LNEP 134

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL-KEH 181
             +  G+    L E++G+K+ ++ CYDLRFPELA   AL+GAE+L + A W   PL +  
Sbjct: 135 AYMQGGSVPPALFELDGVKMAVLICYDLRFPELARRLALEGAEVLFIVAEW---PLARAM 191

Query: 182 HWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFG-VTIAAASEMPALIMAEV 236
           HW  L  ARA++   Y+++    G+ N     G S +IDP+G + +  +S     +  +V
Sbjct: 192 HWKALQQARAIENQFYLLSCNSVGSHNGTDYAGTSMVIDPWGEIIVEGSSTEEEWLQCKV 251

Query: 237 TPERVRQVRAQLPVLNNRR 255
              +  +VR ++PV ++RR
Sbjct: 252 DFSKAAEVRDRVPVFSSRR 270


>UniRef50_Q6SHH5 Carbon-nitrogen hydrolase family protein n=2 Tax=environmental
           samples RepID=Q6SHH5_9BACT
          Length = 255

 Score = 95.5 bits (236), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 69/248 (27%), Positives = 112/248 (45%), Gaps = 15/248 (6%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           EKN E     + QA  +   +  LPE         AD+  K A+L   +    L++ +  
Sbjct: 16  EKNLERTEKFVRQAKADGCDVVVLPEVF--NTGFIADVG-KYAELPNCKTHHALQQFALN 72

Query: 75  NMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAP 133
           N++  +          +A N+ LV    GN VA+Y+KLH ++     E +   +GNE   
Sbjct: 73  NLINIVAGASEKQPNEKAHNIALVFDSHGNEVAKYSKLHPFNY--ANEGKYFTSGNETIK 130

Query: 134 LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALD 193
             E++G+   +  CYDLRFPE+   Q  +  E++ + A W     +E HW  LL ARA++
Sbjct: 131 F-ELDGVACSVFICYDLRFPEI-FRQIAEEVEVIFVIANWPH--TREMHWQNLLIARAIE 186

Query: 194 TTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQL 248
             C++V     GN  +     G S +I+P G  +    +       ++    V + R   
Sbjct: 187 NQCFIVGVNRIGNDGVGLKYNGSSMVINPLGEVLLQTDKKTEYASCDIDTLMVSKTRKDF 246

Query: 249 PVLNNRRF 256
           P L + RF
Sbjct: 247 PFLEDIRF 254


>UniRef50_Q97IH6 Predicted amidohydrolase n=1 Tax=Clostridium acetobutylicum
           RepID=Q97IH6_CLOAB
          Length = 260

 Score = 95.1 bits (235), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 69/262 (26%), Positives = 118/262 (45%), Gaps = 20/262 (7%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A GQ  V     E+  E C + M +AA+  A L   PE  L         S+K  ++
Sbjct: 1   MKIALGQIDVFFEDKERTKEKCLNFMKKAADKKADLIIFPEMTLT------GFSMKVDKI 54

Query: 60  LEGEF--LGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
            E +F  L   + +SK   + +       +  G+  N  +    G  + RY KLH +   
Sbjct: 55  GENKFETLEWFKEKSKEFNIYSGFGFVEGTKKGKN-NFSICSPLGEEILRYTKLHPFSY- 112

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E +    GNEI    ++    +    CYDLRFPE+   +A + +E +++ A W +  
Sbjct: 113 -GNEDKYFYKGNEIV-YCKIGDFNISTFICYDLRFPEI-FQKASKESECILIIANWPK-- 167

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIM 233
           ++   W  L+ ARA++T  Y+ A    G  +     G S +++P+G   A  SE   L++
Sbjct: 168 VRREQWIALIKARAIETQSYIAAVNRVGEGDGLYYSGDSMVVNPYGEITAFKSEKEELLI 227

Query: 234 AEVTPERVRQVRAQLPVLNNRR 255
            ++    V++ R +     +RR
Sbjct: 228 CDININEVKKCREEFRFKEDRR 249


>UniRef50_C1XNR0 Predicted amidohydrolase n=2 Tax=Meiothermus RepID=C1XNR0_MEIRU
          Length = 255

 Score = 95.1 bits (235), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 76/255 (29%), Positives = 113/255 (44%), Gaps = 14/255 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M VA    A     E   +    L++QA +  A +  LPE L       AD +   +   
Sbjct: 1   MKVALVHLATLETPEATLQKALELLSQAHQQGAKVAVLPE-LFPSGYRFADAAFTPS--- 56

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
               L RL +   +  ++ +  +   + P  A    V   AG ++A Y K HL  AF   
Sbjct: 57  ---VLARLEQFCAQTGLSVVAGVLEQAGPRHANRARVVGPAG-VLATYTKTHLIPAFG-- 110

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           E   +  G E+   LE+EG KVGL  C+DLRFPEL    ALQG  + ++P+AW +   + 
Sbjct: 111 EPETMIPGQELV-TLELEGFKVGLAICFDLRFPELFRVYALQGVNLFLIPSAWPKS--RG 167

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
           + W     +RA +   Y+VA     N     S  +DP G  +    E   L + E+ P  
Sbjct: 168 YAWELFCKSRAAENQAYLVAVNHAENPFGAASLAVDPLGQELLRV-EAEGLGLVELDPAF 226

Query: 241 VRQVRAQLPVLNNRR 255
             ++R + PV   RR
Sbjct: 227 PARLRQEFPVFPQRR 241


>UniRef50_C7MFL6 Predicted amidohydrolase n=1 Tax=Brachybacterium faecium DSM 4810
           RepID=C7MFL6_BRAFD
          Length = 477

 Score = 95.1 bits (235), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 65/178 (36%), Positives = 95/178 (53%), Gaps = 10/178 (5%)

Query: 85  VPSTPGRAWNMLVALQAG-NIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVG 143
            P+  GR  N ++    G +    Y K+HL+DAF   ESR V  G E+    E+EG + G
Sbjct: 294 TPADDGRVHNTVIVRGPGWDPHLDYRKIHLFDAFGTDESRTVAPGEELI-TFELEGTRFG 352

Query: 144 LMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGE 203
           + TCYD+RFPE   + A +GA+ ++LP AW  GP K      LL ARALD T  ++AA +
Sbjct: 353 IATCYDVRFPEQFTSLAQRGAQAILLPLAWKEGPGKREQLQLLLRARALDATVVVLAADQ 412

Query: 204 --------CGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN 253
                      + IG+S +I P G+        P L++ ++  E +   RA+LPVL +
Sbjct: 413 SPPADHTGSAPRGIGRSAVIGPLGLVRQELGREPGLLLVDLDLEEIEAARAELPVLRH 470


>UniRef50_C7YHV7 Putative uncharacterized protein n=2 Tax=Nectriaceae
           RepID=C7YHV7_NECH7
          Length = 294

 Score = 94.7 bits (234), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 79/250 (31%), Positives = 120/250 (48%), Gaps = 36/250 (14%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           + A GQ   T+  + N E C  L+A+AA   A +  LPEA     D+ A     S +L E
Sbjct: 3   IAAVGQICSTASVKGNLEQCVRLVAKAARGGAKVLFLPEA----SDYIAPDGQTSLELAE 58

Query: 62  GE----FLGRLRRESKRNMMTTILTIHVPSTP------GRAWNMLVALQAGNIV---ARY 108
            +    F+  L+  ++ + +   + IH    P       R  N  + + A   V   A Y
Sbjct: 59  PQQTSPFVKGLQDAAREHSVAVHVGIHHRPEPEPGAAVHRILNRALYIGADGAVVDSASY 118

Query: 109 AKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPE--LALAQALQG--- 163
            KLH++D   ++ES  V  G  + P  +    ++G + C+DLRFPE  L L+Q   G   
Sbjct: 119 DKLHVFDYGNLRESATVRPGPALTPPFDSPVGRIGSLICFDLRFPEPGLLLSQPGPGSPW 178

Query: 164 ----AEILVLPAAWVRGPLKEH--HWSTLLAARALDTTCYMVAAGECGNKN-----IGQS 212
               A++L  P+A+    L+    HW TLL ARA++T  Y+VAA + G  N      GQS
Sbjct: 179 AGRPAQVLTYPSAFT---LRTGAAHWETLLRARAIETQSYVVAAAQVGRHNEKRASWGQS 235

Query: 213 RIIDPFGVTI 222
            + DP+G  +
Sbjct: 236 IVADPWGRVV 245


>UniRef50_B9CT99 Hydrolase in agr operon (ORF 5) n=2 Tax=Staphylococcus
           RepID=B9CT99_STACP
          Length = 259

 Score = 94.4 bits (233), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 58/199 (29%), Positives = 97/199 (48%), Gaps = 15/199 (7%)

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQES 122
           +F+ RL ++   N++    +I   +  G         + G ++ +  K+HL     + E 
Sbjct: 64  DFISRLAKQFNTNIVAG--SISNKTEKGIYNTAFSVARNGALLNKNDKVHLVPM--LDEP 119

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
           + + AG +     EVEGM V  + CYDLRFPE+A    ++G++++ + A W    L+  H
Sbjct: 120 QYLTAGKDNPNCFEVEGMPVSQLICYDLRFPEVARHSIMEGSKVIFVVAQWTTKNLE--H 177

Query: 183 WSTLLAARALDTTCYMVAAGECG---------NKNIGQSRIIDPFGVTIAAASEMPALIM 233
           W  LL ARA++  C++VA    G         N   G S I+ P G  +  A++ P +I 
Sbjct: 178 WRILLRARAVENHCFIVACNSVGRVNHPNHMTNTYAGHSMIVHPSGEILIEANDGPQVIE 237

Query: 234 AEVTPERVRQVRAQLPVLN 252
            E+  E V   R  +P L+
Sbjct: 238 CEINIEEVDVQRENIPTLD 256


>UniRef50_Q5UF08 Predicted amidohydrolase n=1 Tax=uncultured alpha proteobacterium
           EBAC2C11 RepID=Q5UF08_9PROT
          Length = 276

 Score = 94.4 bits (233), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 82/271 (30%), Positives = 126/271 (46%), Gaps = 18/271 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEA---LLARDDHDADLSVKSAQL 59
           VAA Q+  +    K       L+A+AA   ASL ALPE    L A  +     +    + 
Sbjct: 4   VAALQYCASDDVAKTLHHIQPLIAEAASK-ASLVALPECANYLAASREQLFQKAEWDDES 62

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA- 118
              ++LG + RE    ++   L +        A   L+    G ++A Y K+H++DA   
Sbjct: 63  YSQKWLGNIAREFGIWLLAGSLIMRRRDNNQLANRSLLFGPDGEVIAYYDKIHMFDADVG 122

Query: 119 ----IQESRRVDAGNEIAPLL-EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                +ES    AG   +P++  ++ +  GL  CYD+RF  L    AL GA++ ++PAA+
Sbjct: 123 DGKMYRESASFSAGQ--SPVIAHIDNVPCGLTICYDVRFAHLYRQLALDGAQLFLVPAAF 180

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASEM 228
                K  HW  LL ARA++T CY+VA  + G      K  G S II+P+G  IA A + 
Sbjct: 181 TALSGKA-HWHVLLRARAIETGCYIVAPAQSGTHADGRKTYGHSLIINPWGEIIAEAKDG 239

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            ++I A +      + R  +P L       P
Sbjct: 240 DSIIYAALDLSATARARNAIPSLKTNPVIGP 270


>UniRef50_D2RK67 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Acidaminococcus fermentans DSM 20731
           RepID=D2RK67_ACIFE
          Length = 254

 Score = 94.0 bits (232), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 53/157 (33%), Positives = 84/157 (53%), Gaps = 8/157 (5%)

Query: 102 GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL 161
           G  +A Y K +L   F  +E + +  G E + +++    ++G   CYD+RFP+  +    
Sbjct: 100 GKCIATYRKRNLV-TFNSEEVKLIQNGKE-STVVDTPFGRIGFAICYDVRFPKNFIEMTE 157

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAG----ECGNKNIGQSRIIDP 217
           +  +I+VL AAW    L+  HW  L   RA++   Y++A      E GN   G S I DP
Sbjct: 158 KNVDIIVLSAAWSFPRLE--HWCLLSQCRAIENVSYLLACNCVGTERGNVYFGHSAIYDP 215

Query: 218 FGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
           +G  IAAA     ++ AE+ PE V+++R + PVL +R
Sbjct: 216 WGTKIAAAGIEKTIVSAEINPEHVQEIRKKFPVLRDR 252


>UniRef50_A8I529 Carbon-nitrogen hydrolase family protein n=8 Tax=Proteobacteria
           RepID=A8I529_AZOC5
          Length = 282

 Score = 94.0 bits (232), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 80/258 (31%), Positives = 115/258 (44%), Gaps = 23/258 (8%)

Query: 17  NAEICASLM-AQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRN 75
           N    ASL+ A  A +   L  LPE      D  A     +    +GE    ++  +K+ 
Sbjct: 31  NLATAASLIEAAVAADKPDLVVLPEYYAFLGDTPAQAQDAAETFPDGESYQLMKGLAKK- 89

Query: 76  MMTTILTIHVPSTPGRAWN-----MLVALQAGNIVARYAKLHLYD-----AFAIQESRRV 125
                + IH  S   R  N      +V    G  +ARY K+HL+D         +ES  V
Sbjct: 90  ---LKVAIHAGSVAEREGNSFYNTTVVFGPDGEELARYRKIHLFDVEITGGTVYRESDTV 146

Query: 126 DAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWST 185
             G ++    E+ G  VG   CYD+RFPEL      +GA+I+VLPAA+     K+ HW  
Sbjct: 147 SRGEDVV-TYELGGKTVGCAICYDIRFPELFRKLRDKGADIIVLPAAFTLMTGKD-HWEI 204

Query: 186 LLAARALDTTCYMVAAGECGNKN------IGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
           L  ARA++T  + +A G+ G          G S +IDP+G   A AS+        +   
Sbjct: 205 LARARAIETQTWFLAVGQTGPHAGGKKWCWGHSMVIDPWGHITAQASDGVGFTTGRLEFG 264

Query: 240 RVRQVRAQLPVLNNRRFA 257
              +VRA +PV N+   A
Sbjct: 265 YTEKVRANVPVANHHVLA 282


>UniRef50_A5VIE2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=10 Tax=Lactobacillales RepID=A5VIE2_LACRD
          Length = 261

 Score = 93.6 bits (231), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 68/246 (27%), Positives = 120/246 (48%), Gaps = 14/246 (5%)

Query: 16  KNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQLLEGEFLGRLRRESK 73
           +N +     + +AA + A +  LPE   +    D  A+L+ ++ Q  + +F   L  +++
Sbjct: 19  ENYQKAKQAIEEAANHHADIVVLPEMWNIGYALDQLAELADENGQKTQ-QFFSELALKNQ 77

Query: 74  RNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAP 133
            N++    ++ V +         V  Q GN+++ Y K+HL+    + E + ++AG +   
Sbjct: 78  INIVGG--SVAVRNGQSFFNTTYVYDQNGNLISSYEKVHLFGL--MNEDQYLEAGQK-EN 132

Query: 134 LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALD 193
             ++ G+      CYDLRFPE     A  G +IL  PA W    +++  W  +L +RA++
Sbjct: 133 HFKLAGIPSASFICYDLRFPEWIRTVARYGTDILYFPAEWPSKRIEQ--WKIMLRSRAIE 190

Query: 194 TTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLP 249
              ++VA    G    N   G S +IDP G  I  A E+  +  AE+   ++ QVR  +P
Sbjct: 191 NQAFVVAVNRVGTDLENSFNGHSLVIDPLGQVIHDAGEVEQVSYAEIDLAQLAQVRGPIP 250

Query: 250 VLNNRR 255
           V  +RR
Sbjct: 251 VFKDRR 256


>UniRef50_O76464 Nitrilase homolog n=6 Tax=Sophophora RepID=NFT1_DROME
          Length = 460

 Score = 93.6 bits (231), Expect = 6e-18,   Method: Compositional matrix adjust.
 Identities = 80/267 (29%), Positives = 123/267 (46%), Gaps = 19/267 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL--- 59
           +A GQ   TS    N      L+ +A   +A +  LPE      D   +   ++ +L   
Sbjct: 35  IAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECC----DFVGESRTQTIELSEG 90

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFA 118
           L+GE + + R  +K N +   L         + +N  V L + G + A Y KLH++D   
Sbjct: 91  LDGELMAQYRELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTT 150

Query: 119 ----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               ++ES  V  G  +   +     ++GL  CYDLRF E A+     GA +L  P+A+ 
Sbjct: 151 KEVRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFT 210

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAASEMP 229
               K  HW  LL ARA++T C++VAA + G  N      G S I+ P+G  +A  SE  
Sbjct: 211 YATGKA-HWEILLRARAIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQE 269

Query: 230 ALI-MAEVTPERVRQVRAQLPVLNNRR 255
             I  AEV    ++ +   +P   +RR
Sbjct: 270 LDIGTAEVDLSVLQSLYQTMPCFEHRR 296


>UniRef50_Q2NAB0 Nitrilase 1 like protein n=3 Tax=Sphingomonadales
           RepID=Q2NAB0_ERYLH
          Length = 267

 Score = 93.2 bits (230), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 57/168 (33%), Positives = 88/168 (52%), Gaps = 12/168 (7%)

Query: 102 GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G     Y K+H++D       + +ES     G E+  + +    ++GL  CYDLRFP L 
Sbjct: 96  GESPVHYDKIHMFDVDLADGESWRESNAYRPGEEVVLVDDTPVGRLGLTICYDLRFPALF 155

Query: 157 LAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQ 211
                  A+ + +PAA+ R P    HW TL+ ARA++ + ++VAA      E G K  G 
Sbjct: 156 EELGNARADCIAIPAAFTR-PTGAAHWHTLVRARAIEASAFVVAAAQVGEHEDGRKTYGH 214

Query: 212 SRIIDPFG-VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
           S ++DP+G V +  + + P L  A++   R+ +VR Q+P L NRR  P
Sbjct: 215 SLVVDPWGEVLLDMSGDKPGLGFADIDLARIEEVRRQVPSLANRRPIP 262


>UniRef50_A4BGL8 Predicted amidohydrolase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BGL8_9GAMM
          Length = 271

 Score = 93.2 bits (230), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 79/270 (29%), Positives = 117/270 (43%), Gaps = 21/270 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           V A Q   T     N       +A A   D  +  LPE        D        +  +G
Sbjct: 7   VCAVQMTSTDSLNDNLNWIDQQLANADLQDVQMLVLPETFALFGVKDQSALADQERAFDG 66

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG-----RAWNMLVALQAGNIVARYAKLHLYDA- 116
             +G+  R+  +     I+   VP         RA   +V    G +V  Y K+HL+DA 
Sbjct: 67  S-VGQAVRQWAKGYQVWIVAGTVPVMTDEDRLPRARCHVVDAD-GELVGFYDKIHLFDAE 124

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                 A +ES     G+++  LL   G ++GL  CYDLRFPEL  A   QGA+ + LP+
Sbjct: 125 VGDRQGAYRESDSYSGGDKVVTLLTPWG-RLGLSVCYDLRFPELFRALNDQGADFVTLPS 183

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAAS 226
           A+      E HW  L  ARA++    ++A  +CG+ +      G S I+D +G  + +  
Sbjct: 184 AFT-AKTGEAHWEPLCRARAIENGYSLIAVNQCGDHDAKRSTWGHSMIVDAWG-RVESIG 241

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             P L   ++ P   + +R  LPV  NRR 
Sbjct: 242 LDPGLAFFKLDPAADQVIRNTLPVNANRRL 271


>UniRef50_A3DL17 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Staphylothermus marinus F1 RepID=A3DL17_STAMF
          Length = 273

 Score = 93.2 bits (230), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 53/183 (28%), Positives = 90/183 (49%), Gaps = 4/183 (2%)

Query: 77  MTTILTIHV---PSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQESRRVDAGNEIA 132
           + T + IH      TP +  +  + +  +G I   Y+K+HL+DA+  +ES     G  ++
Sbjct: 80  LDTYMLIHFIEKTDTPPKTMSSSILVHPSGRIDKVYSKMHLFDAYGYRESDYFLPGRTLS 139

Query: 133 PLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARAL 192
             L    ++  +  CYDLRFPEL  + A + A  + + A WVRGPLKE     L  AR+ 
Sbjct: 140 RPLVFNHVRFYVAICYDLRFPELFRSYARKDAYGVFIHAGWVRGPLKEEILDLLARARSH 199

Query: 193 DTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLN 252
           + T Y++ + + G + +G+S +  P G            +   + P+ V + R  +PV+ 
Sbjct: 200 ENTMYIILSDQTGKQYVGRSGVFSPHGFREIDMGYRRGYVEWPINPDDVLEARKVVPVVE 259

Query: 253 NRR 255
             R
Sbjct: 260 QSR 262


>UniRef50_C6B8T0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM1325
           RepID=C6B8T0_RHILS
          Length = 287

 Score = 92.8 bits (229), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 75/254 (29%), Positives = 115/254 (45%), Gaps = 27/254 (10%)

Query: 22  ASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTIL 81
           A LM +A      L  LPE         AD    + ++  GE    ++R +K N     +
Sbjct: 22  ARLMREAMIGRPDLIVLPEHFDWLGGTVADKRRAADRIPGGEAYVLVQRFAKDNA----V 77

Query: 82  TIHVPS------TPGRAWNMLVALQA-GNIVARYAKLHLYDAFA-----IQESRRVDAGN 129
            +H  S         R +N  V   A G  V  Y K+HL+D  A       ES  V  G 
Sbjct: 78  WVHAGSLMERRGQDHRVYNTTVVFNAKGEEVGLYRKIHLFDITAPDGKTYSESAAVAPGR 137

Query: 130 EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAA 189
           ++  + E++G ++G   CYDLRF  L    A +  +I VLPAA+      + HW  L  A
Sbjct: 138 DLF-IYELDGHRIGCAICYDLRFSRLFDRLAEEKVDIFVLPAAFTY-QTGQAHWEVLCRA 195

Query: 190 RALDTTCYMVAAGECGN---------KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
           RA++   Y  A G+CG+         +  G S + DP+G  +A A     +++ E+ P R
Sbjct: 196 RAIEFQAYFAACGQCGSYAMRDGELRRTFGHSMVCDPWGQIVARAENDVCVLVVEIDPAR 255

Query: 241 VRQVRAQLPVLNNR 254
           + +VR  +P+  +R
Sbjct: 256 LPEVRRLIPMAEHR 269


>UniRef50_B2HTJ8 Predicted amidohydrolase n=18 Tax=Acinetobacter RepID=B2HTJ8_ACIBC
          Length = 274

 Score = 92.4 bits (228), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 76/261 (29%), Positives = 117/261 (44%), Gaps = 26/261 (9%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           E N ++  SL+ Q+   +ASL   PE  +      A    ++A+  E     RL + + +
Sbjct: 16  ESNFQVIESLIQQSKAQNASLIVFPENFVC---FAAGKQRETAEQFE-SIQQRLEKLAHQ 71

Query: 75  NMMTTIL-TIHVPSTP-------GRAWNMLVALQAGNIVARYAKLHLYDA------FAIQ 120
             +  +  T+  P  P       GR   + + +      ARY K+HL+D          Q
Sbjct: 72  YQIWIVAGTLPCPFRPDGSIIQDGRVRTVSLCISPERTEARYDKIHLFDVQVGDAVGGYQ 131

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ESR  + G ++       G  +GLM CYDLRFPELAL    QGA +L  PAA+      +
Sbjct: 132 ESRFFEPGTDVVVTSTPFG-NIGLMVCYDLRFPELALTLRQQGAHLLTAPAAFTY-TTGQ 189

Query: 181 HHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAA-ASEMPALIMA 234
            HW  LL ARA+D+ CY++ A + G      +  G +   D  G  ++    E   LI  
Sbjct: 190 MHWQLLLQARAMDSQCYVLGAAQQGWHGEKRQTWGHAGATDSRGQVLSMIGYEGNGLITV 249

Query: 235 EVTPERVRQVRAQLPVLNNRR 255
                    VR  +P++ +R+
Sbjct: 250 PFDLAAQELVRTSMPLMMHRK 270


>UniRef50_Q7MHE3 Predicted amidohydrolase n=69 Tax=Proteobacteria RepID=Q7MHE3_VIBVY
          Length = 300

 Score = 92.0 bits (227), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 80/270 (29%), Positives = 127/270 (47%), Gaps = 23/270 (8%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE-ALL--ARDDHDADLSVKSAQL 59
           +A  Q   TS    N         QAA   ASL   PE ALL   R+D+      + A+ 
Sbjct: 30  IAIIQMTSTSDCTDNVAYIEHWAEQAALQGASLVVTPENALLFGGREDYH-----QHAEP 84

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGR--AWNMLVALQAGNIVARYAKLHLYDAF 117
           L    L +   +  + +  T++   +P   G       LV    G  +  Y+KLH++D  
Sbjct: 85  LGNGPLQQAMAQLAKRLAVTLVIGSMPIRQGHDVTTTSLVFGPNGERLGHYSKLHMFDVE 144

Query: 118 A------IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES    AG+  + +    G ++GL  CYD+RFP L      +GA+IL++PA
Sbjct: 145 VSDGHGHYRESDSFLAGDRSSVVATPIG-RLGLSICYDVRFPALYQTLRQKGADILLVPA 203

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAAS 226
           A+      E HW  LL ARA++  C+++AA + G      +  G S +IDP+G  +A   
Sbjct: 204 AFT-AVTGEAHWEVLLRARAIENQCWVIAAAQGGMHSASRETWGHSMVIDPWGKVVAQLP 262

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           +   L++AE+       +R ++PV+ + RF
Sbjct: 263 QQGDLLLAEIDLALSDTIRRKMPVVKHSRF 292


>UniRef50_C4QCM8 Nitrilase-related n=1 Tax=Schistosoma mansoni RepID=C4QCM8_SCHMA
          Length = 541

 Score = 92.0 bits (227), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 66/198 (33%), Positives = 98/198 (49%), Gaps = 28/198 (14%)

Query: 90  GRAWNMLVALQA-GNIVARYAKLHLYD-----AFAIQESRRVDAGNEI----APLLEVEG 139
           G+ +N        G +V  Y KLHL+D      FA +ES  + +G E      PL   E 
Sbjct: 343 GKLYNCCATYNPDGELVGLYRKLHLFDIDIPGQFAFKESASLSSGKETFSFEIPLKNSEN 402

Query: 140 ----MKVGLMTCYDLRFPELALAQALQ-GAEILVLPAAW--VRGPLKEHHWSTLLAARAL 192
               ++VG+  CYD+RFPEL+L  A Q G ++L+ PAA+    G L   HW  L  ARAL
Sbjct: 403 KISVIRVGIGICYDIRFPELSLLYANQLGCQLLLFPAAFNPKTGSL---HWELLGRARAL 459

Query: 193 DTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQ 247
           DT CY+       N  +      +S I  P+G+ IA   +   +I A++    ++ VR  
Sbjct: 460 DTQCYVGMCSPACNLELDYISHAESLITSPWGIVIAKGGKEEEIITADLDFSELKCVRES 519

Query: 248 LPVLNNRR---FAPPQLL 262
           +P+   RR   +  P+L+
Sbjct: 520 IPIGRQRRLDIYTTPKLV 537


>UniRef50_C2BXL2 Cyanide hydratase n=1 Tax=Listeria grayi DSM 20601
           RepID=C2BXL2_LISGR
          Length = 268

 Score = 91.7 bits (226), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 73/248 (29%), Positives = 118/248 (47%), Gaps = 16/248 (6%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARD--DHDADLSVKSAQLLEGEFLGRLRRES 72
           +KN +     + +AA + A +  LPE           AD +  +    +G FL RL  + 
Sbjct: 25  DKNYQAIEQAVIEAANSGADIVVLPEMWNTGYCLSELADFADPNGDRTKG-FLIRLALQQ 83

Query: 73  KRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVDAGNEI 131
           K  ++   + I   S      N++ A+ + G+++A Y K+H +    + E   +  GN  
Sbjct: 84  KVTIIGGSVAI---SEEDHFSNIMYAVAKDGDLLASYRKVHPFQG--MDEHTYIRPGNS- 137

Query: 132 APLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARA 191
           A L  +  +      CYD+RFPE     A  GAE+L + A W    + +  W  LL ARA
Sbjct: 138 ANLFRIGDLACAGFICYDIRFPEWLRKHAANGAEVLFVSAQWPSARITQ--WKQLLIARA 195

Query: 192 LDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQ 247
           ++   ++VA    G    N+  G S +I P G  IA A + P  ++AE+    V++VR  
Sbjct: 196 IENQAFVVAVNRVGSDPANQFGGNSLVIHPSGEIIAEADDTPQNLLAEINLADVKKVREA 255

Query: 248 LPVLNNRR 255
           +PVL +RR
Sbjct: 256 MPVLADRR 263


>UniRef50_Q3SLE9 Carbon-nitrogen hydrolase n=101 Tax=Proteobacteria
           RepID=Q3SLE9_THIDA
          Length = 319

 Score = 91.3 bits (225), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 80/273 (29%), Positives = 131/273 (47%), Gaps = 23/273 (8%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q A       N      L+  A +  A L  LPE        D+   V  A+  EG
Sbjct: 31  VAAIQMASGPSVPANLAEAERLIELAVQAGARLVVLPEFFCIMAMKDS--YVVKAREAEG 88

Query: 63  E-----FLGRLRRESKRNMMTTILTIHVPSTPGRAWN-MLVALQAGNIVARYAKLHLYD- 115
           +     FL R+ ++ K  ++   + +   S P +  N  LV  + G  +ARY K+HL+  
Sbjct: 89  DGPIQTFLARMAKKHKVWLIGGSVPLEA-SVPNKVRNSCLVYDERGKQIARYDKIHLFGL 147

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  QE++ ++ G+++  +    G ++GL  CYDLRFPEL   +A+   +I+V+P+A
Sbjct: 148 DLGNERYQEAKLIEPGDKVVVVNSPFG-RIGLSVCYDLRFPELY--RAMPDVDIIVVPSA 204

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGE-----CGNKNIGQSRIIDPFGVTIAAASE 227
           +        H+ TL+ ARA++   Y++A  +      G +  G S I+DP+GV +     
Sbjct: 205 FT-ATTGRAHFETLVRARAIENLAYVIAPAQGGYHLSGRETHGDSMIVDPWGVVLDRLPR 263

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
              +++A + P     +R  LP L + RF P Q
Sbjct: 264 GSGVVIANINPAYQASLRKSLPALQH-RFIPCQ 295


>UniRef50_A8ZSH3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfococcus oleovorans Hxd3 RepID=A8ZSH3_DESOH
          Length = 270

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 61/184 (33%), Positives = 93/184 (50%), Gaps = 12/184 (6%)

Query: 78  TTILTIHVP-STPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLL 135
           + ++   VP + P    N LV + + G    RY K+HL+ A    E R    G   A + 
Sbjct: 79  SMVIAGSVPEAGPDGICNTLVVMDRDGREAGRYRKIHLFSAGG--EERFFAKGKAWA-VC 135

Query: 136 EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTT 195
           +    K+GLM CYDLRFPEL    AL GA  +++PA W    +   HW+ LL ARA++  
Sbjct: 136 DTAAGKLGLMICYDLRFPELCRVLALDGAACVIVPAQWPEARID--HWNALLKARAIENQ 193

Query: 196 CYMVAAGECGNKNI----GQSRIIDPFGVTIA-AASEMPALIMAEVTPERVRQVRAQLPV 250
            ++V A  CG+       G S+++ P G  +A A ++ P +I+A +    +   R  +P 
Sbjct: 194 LFVVGANRCGHDPSLAYGGGSQVVSPTGEVLALARADAPQVILANLDRAVMENFRKHIPC 253

Query: 251 LNNR 254
           L  R
Sbjct: 254 LQER 257


>UniRef50_A8VU18 Amidohydrolase-like protein n=1 Tax=Bacillus selenitireducens MLS10
           RepID=A8VU18_9BACI
          Length = 168

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 53/166 (31%), Positives = 86/166 (51%), Gaps = 10/166 (6%)

Query: 95  MLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPE 154
           M V  ++G  V  Y+KLHL+    + E + +  G        +E +    M CYD+RFPE
Sbjct: 1   MPVIDRSGEQVKAYSKLHLFRL--MNEDKYLSEGTGDG-FFTLEDVPCTGMICYDIRFPE 57

Query: 155 LALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIG 210
                AL+ AE+  + A W    +   HW+ LL +RA++  CY+VA    G    N   G
Sbjct: 58  WVRHHALKEAEVFFVVAEWPHARID--HWTALLTSRAIENQCYIVACNRVGADPDNVFGG 115

Query: 211 QSRIIDPFG-VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            S +IDP+G V + A+ +   ++M ++  +  + VR ++PV  +RR
Sbjct: 116 TSMVIDPWGKVLLKASEDREEILMIDIDLQESKSVRKRIPVFEDRR 161


>UniRef50_C0F0M8 Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM
           3353 RepID=C0F0M8_9FIRM
          Length = 273

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 63/257 (24%), Positives = 112/257 (43%), Gaps = 29/257 (11%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           E N E       +A EN       PE  L     + + + + ++  +  F   + ++ K 
Sbjct: 16  EDNKEKVEQFFKKAEENQVDCLVFPEMTLTGFSMNVEETGEKSEN-QKHFFEEMSKKYK- 73

Query: 75  NMMTTILTIHVPSTP------------GRAWNMLVALQAGNIVARYAKLHLYDAFAIQES 122
                ILT+   + P               +N L   + G +   YAK+H + ++   E 
Sbjct: 74  -----ILTVFGYTEPVPEERLKEHPNWNHYYNRLGIAENGELKLNYAKIHPF-SYGF-EG 126

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
                G ++  + E +G  +G   CYDLRFPE+    + + +EI+ + A W +  + +  
Sbjct: 127 EYYQGGRKLKSV-EWKGTTLGAFVCYDLRFPEI-FQISSEKSEIIFVIANWPKSRIDQ-- 182

Query: 183 WSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           W TLL ARA++   +MV     G  +     G S I  P G  +    E   L++ ++ P
Sbjct: 183 WDTLLKARAIENQVFMVGVNRTGEGDGLHYNGHSAIYSPNGEAVTTIREEECLLIGDINP 242

Query: 239 ERVRQVRAQLPVLNNRR 255
           E ++++R   P+ N+RR
Sbjct: 243 EEIKEMRKTFPMKNDRR 259


>UniRef50_C7QHA6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QHA6_CATAD
          Length = 264

 Score = 90.5 bits (223), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 65/179 (36%), Positives = 92/179 (51%), Gaps = 11/179 (6%)

Query: 84  HVPSTP-GRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKV 142
           +V  TP G  +N  V        A+Y K+H +  F+  E   +  G +I  +    G  +
Sbjct: 90  YVERTPEGILYNTAVFRGPDGKQAQYRKIHRF-GFSEGEVTLMGPGKDIVTVSSPWGT-L 147

Query: 143 GLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE-HHWSTLLAARALDTTCYMVAA 201
           GL TCYDLRFPEL      QG E +V+ +AW   P K   HW  LL ARA++   ++ A 
Sbjct: 148 GLATCYDLRFPELFRRLLNQGMEHMVMCSAW---PAKRIEHWRVLLKARAIENQVFVFAT 204

Query: 202 GECG-NKNI---GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
              G N  +   G+S +IDP+G  +A A     ++  +V P  V Q R+ LPVLN+RR 
Sbjct: 205 NCVGTNGGVALGGRSAVIDPWGNVVAEAGTGEEVLRVDVDPALVAQTRSALPVLNDRRL 263


>UniRef50_B9HD27 Predicted protein n=8 Tax=Magnoliophyta RepID=B9HD27_POPTR
          Length = 370

 Score = 90.1 bits (222), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 81/278 (29%), Positives = 122/278 (43%), Gaps = 46/278 (16%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPE-----------ALLARD-DHDADLSV 54
           Q +VT+  E+N       + +AA   A L  LPE            + A D D   + S 
Sbjct: 94  QLSVTADKERNIAHARKAIEEAAAKGAKLVMLPEIWNSPYSNDCFPVYAEDIDAGGEASP 153

Query: 55  KSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVALQA-GNIVARYAKLH 112
            +A L E   L          +  TI+   +P   G R +N      + G + A++ K+H
Sbjct: 154 STAMLSEAAGL----------LKVTIVGGSIPERSGDRLYNTCCVFDSDGKLKAKHRKIH 203

Query: 113 LYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           L+D          ES+ + AG E   +++ E  ++G+  CYD+RF ELA+  A +GA ++
Sbjct: 204 LFDIDIPGKITFIESKTLTAG-ETPTIVDTEVGRIGIGICYDIRFQELAIIYAARGAHLI 262

Query: 168 VLPAAW--VRGPLKEHHWSTLLAARALDTTCYM--------VAAGECGNKNIGQSRIIDP 217
             P A+    GPL   HW  L  ARA D   Y+        VAAG       G S ++ P
Sbjct: 263 CYPGAFNMTTGPL---HWELLQRARAADNQLYVATCSPARDVAAGYVA---WGHSTLVGP 316

Query: 218 FGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           FG  +A       +I+AE+    +   R  LP+   RR
Sbjct: 317 FGEVLATTEHEEDIIIAEIDYSLLEVRRTNLPLTKQRR 354


>UniRef50_A6DKQ0 Carbon-nitrogen hydrolase family protein n=1 Tax=Lentisphaera
           araneosa HTCC2155 RepID=A6DKQ0_9BACT
          Length = 286

 Score = 90.1 bits (222), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 70/259 (27%), Positives = 121/259 (46%), Gaps = 20/259 (7%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLA----RDDHDADLSVKSAQLLEGEFLGRLRR 70
           E N +    L+A AA++ A++    E  L+    R+ +      + AQ ++ E L   ++
Sbjct: 16  EANKKQHLKLIADAAKSGANIICTQELFLSNYFCREQNTEHF--QYAQKIDQELLADFQQ 73

Query: 71  ESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGN 129
            +K + +   L+    +  G  +N  V + A G  + +Y KLH+      +E      GN
Sbjct: 74  CAKNHGVVLALSFFEEALNGVYYNTSVIIDADGTYLGKYRKLHIPQDPYFEEKFYFTPGN 133

Query: 130 EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA--WV------RGPLKEH 181
              P+ E +  K+ L+ C+D  FPE A    L GAEI+++P A  W+       G  + H
Sbjct: 134 LGVPVFETQFGKISLIICWDQWFPETARLACLAGAEIILVPTAIGWLPDEKEEHGAQQAH 193

Query: 182 HWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIA-AASEMPALIMAEV 236
            W+ +    A+   CY  A    G +      GQS I D +G T+A A+S    ++ A++
Sbjct: 194 SWTQVQLGHAVANGCYYAAVNRVGIEEPIQFWGQSFISDFYGQTLAQASSNEEEILFADL 253

Query: 237 TPERVRQVRAQLPVLNNRR 255
             +++R+ R   P   +RR
Sbjct: 254 DLKQLREHRQIWPFFRDRR 272


>UniRef50_C7TF35 Hydrolase, carbon-nitrogen family n=17 Tax=Lactobacillales
           RepID=C7TF35_LACRL
          Length = 260

 Score = 89.7 bits (221), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 71/249 (28%), Positives = 117/249 (46%), Gaps = 19/249 (7%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ---LLEGEFLGRLRRE 71
           EKN +  A+ +A+AA+  A +  LPE  +    +D +    +A    L    FL  L   
Sbjct: 19  EKNFQTVANAVAEAAQQGAEVVVLPE--MWNTGYDLEHLTTTANPDGLRTKAFLSAL--- 73

Query: 72  SKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNE 130
           +++  +  +      +  G  +N  L   Q G  +A+Y K+H +    + E + + AG  
Sbjct: 74  AQQYHLAIVGGSVAAAENGHFYNRSLTVDQRGRQLAKYDKVHRFRL--MNEEKFITAGAT 131

Query: 131 IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAAR 190
                   G+   +  CYDLRFPE     A  G ++  LPA W    L +  ++ LLAAR
Sbjct: 132 ADHF--TLGVPASVAICYDLRFPEWFRRMASDGTQLFFLPAEWPTPRLPQ--FNALLAAR 187

Query: 191 ALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRA 246
           A++   Y+VA    GN       GQS+++DPFG  +    + P + +  +  +R+   R 
Sbjct: 188 AIENQAYVVAVNRVGNDPNNAFGGQSQVVDPFGERLLKLDDQPQVRIVTIDLDRIAAARQ 247

Query: 247 QLPVLNNRR 255
           Q+PV  +RR
Sbjct: 248 QIPVFTDRR 256


>UniRef50_A1SMV4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Nocardioides sp. JS614 RepID=A1SMV4_NOCSJ
          Length = 262

 Score = 89.7 bits (221), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 87/261 (33%), Positives = 121/261 (46%), Gaps = 14/261 (5%)

Query: 1   MLVAAGQ-FAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA-DLSVKSAQ 58
           M VAAGQ  +V+   + N    A L   AA  D  +  LPEA L   D  A D  +  A+
Sbjct: 1   MRVAAGQAVSVSGDLDANVRTAARLTRLAATQDVRVLVLPEAFLTGYDVAAFDGPLPDAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
            L+G +L  LR ES   + T ++   +     R  + +V    G   A Y K HL D   
Sbjct: 61  GLDGGWLDPLRAESAAGV-TVVVGTALRRGAERRLSQIVVRPDGRADAPYDKQHL-DGLE 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
                  D G  I    EV+G+++GL  CYD  FPE A A A  GA   +  AA+   P 
Sbjct: 119 KTFFTVGDHGTSI----EVDGLELGLSICYDGCFPEHAQAAARDGAVGYLSSAAYF--PG 172

Query: 179 KEHHWSTLLAARALDTTCYMVAA---GECGN-KNIGQSRIIDPFGVTIAAASEMPALIMA 234
             H      AARA++   Y+V +   G CG  + IG S + DP G  IA  +E   L +A
Sbjct: 173 GAHRRDLYYAARAVENGMYVVFSGLTGRCGGFEFIGGSAVYDPEGRPIARLAEEEGLAIA 232

Query: 235 EVTPERVRQVRAQLPVLNNRR 255
           ++    V Q RA   ++++ R
Sbjct: 233 DLDAGLVAQTRATHTMISDHR 253


>UniRef50_Q6AMZ4 Putative uncharacterized protein n=1 Tax=Desulfotalea psychrophila
           RepID=Q6AMZ4_DESPS
          Length = 258

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 56/158 (35%), Positives = 87/158 (55%), Gaps = 8/158 (5%)

Query: 102 GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL 161
           G+I+  Y K+HL+  FA  E+  + AG EI+ +    G+ +G+ TC+DLRFPEL      
Sbjct: 101 GDILGNYRKIHLF-GFASLETEILSAGQEISVINTKLGI-IGMATCFDLRFPELFRKMVD 158

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-NKNI---GQSRIIDP 217
           QG EI ++ AAW    L +  W+ L   RAL+    +++A   G +K +   G S I+ P
Sbjct: 159 QGTEIFLICAAWPLARLAD--WALLNRVRALENQALLISANARGMSKGVQLAGNSMIVGP 216

Query: 218 FGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            G  +A A +M   I AE+    V++ R   P L++R+
Sbjct: 217 NGQILAQADDMDNSISAEINLNAVKEARCSFPALSSRK 254


>UniRef50_A8MG18 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Bacteria RepID=A8MG18_ALKOO
          Length = 261

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 54/161 (33%), Positives = 83/161 (51%), Gaps = 11/161 (6%)

Query: 100 QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQ 159
           + G  +A Y K HL+      E +  + G+ I  + E++G+K G++ CYD+RF EL    
Sbjct: 101 KQGECIAEYDKTHLFSYMG--EDQYFEKGSGIT-VFELDGIKCGIVICYDIRFVELVRTL 157

Query: 160 ALQGAEILVLPAAWVRGP-LKEHHWSTLLAARALDTTCYMVAAGECG--NKNI--GQSRI 214
           ALQ  +IL + A W   P L+ HHW  L  ARA++   ++     CG   + I  G S +
Sbjct: 158 ALQEIKILFVVAQW---PMLRIHHWQILNEARAIENQIFVACVNSCGRAGETIYGGNSAL 214

Query: 215 IDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           IDP+G  I  AS    +I   +    V ++R  + V  +RR
Sbjct: 215 IDPWGEVILRASNQEEIITGNLDLSIVEKIRDTIHVYKDRR 255


>UniRef50_A7FDR9 Hydrolase, carbon-nitrogen family protein n=45
           Tax=Enterobacteriaceae RepID=A7FDR9_YERP3
          Length = 289

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 52/166 (31%), Positives = 87/166 (52%), Gaps = 13/166 (7%)

Query: 102 GNIVARYAKLHLYDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
           G + ARY K+H++D          +ES     G ++  +++    ++G+  CYDLRFP L
Sbjct: 107 GELKARYDKIHMFDVDINDIHGHYRESDTYQPGQQLT-VVDTPVGRLGMTICYDLRFPGL 165

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIG 210
             A   QGAEI+ +PAA+ +    E HW TLL ARA++  C ++AA + G      +  G
Sbjct: 166 FQALRAQGAEIISVPAAFTK-MTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWG 224

Query: 211 QSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            +  +D +G  I    +  A +   +    ++ +R Q+PV+ + RF
Sbjct: 225 HTMAVDAWGKIIGHNPDAVAALKVRIETAGLKTIRNQMPVMQHNRF 270


>UniRef50_Q46AW4 Putative amidohydrolase n=1 Tax=Methanosarcina barkeri str. Fusaro
           RepID=Q46AW4_METBF
          Length = 287

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 54/168 (32%), Positives = 85/168 (50%), Gaps = 11/168 (6%)

Query: 93  WNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLR 151
           +N+    ++G +   Y K H +      E+     G+ I P+ L+ + +K+G   CYDLR
Sbjct: 115 YNLGFCFESGTLAGSYRKTHPFKT----ENNYFSKGDSIEPISLKKQNLKIGFEICYDLR 170

Query: 152 FPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----K 207
           FPE+A   +L G+++LV  AA+   P  E HW+ L  ARA++     +A    G+     
Sbjct: 171 FPEVARKLSLAGSDLLVTTAAF-PNPRSE-HWNILAKARAIENQIPHIACNRIGSAPDCS 228

Query: 208 NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
             G S IID +G   A A     LI+ ++   R  +VR  +PV  N+R
Sbjct: 229 YFGNSMIIDAWGEVKADAGNKECLIVHDLDLSRKNEVRKMIPVFENQR 276


>UniRef50_Q6MPB5 Putative amidohydrolase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MPB5_BDEBA
          Length = 276

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 54/170 (31%), Positives = 90/170 (52%), Gaps = 17/170 (10%)

Query: 102 GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G +   Y K+HL+D        ++ES     G +   +++++G KVG   CYD+RF EL 
Sbjct: 106 GEVQPTYQKMHLFDIQLDGQAPLRESDVFRHG-QTPNVIDIDGWKVGEAICYDVRFAELF 164

Query: 157 LAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN---------K 207
              A +  ++++LPAA++     E HW  LL ARA++   Y++AA + G          +
Sbjct: 165 SQYARREVDVILLPAAFLV-KTGEAHWEILLRARAIENQSYVIAAAQGGTHTGLRGGTRE 223

Query: 208 NIGQSRIIDPFGVTIAAASE-MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             G S IIDP+G  +    +  P + +++ T ER+  VR Q+P+  +RR 
Sbjct: 224 TYGHSLIIDPWGAVVGQVEKRQPGVTISKFTRERIDSVRRQIPMKFHRRL 273


>UniRef50_C9N4S0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Streptomyces RepID=C9N4S0_9ACTO
          Length = 265

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 58/169 (34%), Positives = 81/169 (47%), Gaps = 8/169 (4%)

Query: 96  LVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
           LV    G   A Y K+H +  F   E+  + AG E+  +   E + +GL TCYDLRFPE 
Sbjct: 97  LVFSPEGERAAAYRKIHRF-GFDKGEAVLMGAGEELVTVALPETI-LGLATCYDLRFPEQ 154

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQ 211
                  GAE LV+ A W     +  HW+ L  ARA++   Y++A G  G     +  G 
Sbjct: 155 FRGLVDAGAETLVVSAGWPE--RRRSHWTLLAQARAVENQAYVLAVGSAGTHAGVEQAGH 212

Query: 212 SRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           S ++DP+G  +A A     ++  E  P R    R Q P L +RR    Q
Sbjct: 213 SIVVDPWGEVLAEAGAAEEVLTVEFDPARATTTREQFPALKDRRLGLAQ 261


>UniRef50_Q5KLT5 Nitrilase-like protein, putative n=2 Tax=Filobasidiella neoformans
           RepID=Q5KLT5_CRYNE
          Length = 356

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 79/303 (26%), Positives = 133/303 (43%), Gaps = 53/303 (17%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q   TS    N +I   ++  A    A    LPEA    +    +    S  L + 
Sbjct: 46  VAVCQLRSTSDPVHNLKISEKVIRNAVAAGAKACFLPEASDFINPSKTESRKFSHPLPKH 105

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG-----RAWNMLVAL-QAGNIVARYAKLHLYDA 116
           E+   L+R +K   +  ++++ V   P      R +N  V + + G I+A Y K+HL+D 
Sbjct: 106 EYTIGLQRLAKE--LGIVISVGVHEGPEDESEERVYNTHVLIGKDGGILASYRKIHLFDV 163

Query: 117 FAIQ---------------ESRRVDAGNEIAPLLEVEGM-KVGLMTCYDLRFPELALAQA 160
              +               ES R+ AG  + P +EVEG+  +GL  CYD+RFPEL++   
Sbjct: 164 ELSKPPAPDGTPRPPQRTGESERILAGQAVTPPVEVEGIGNIGLEICYDIRFPELSIILT 223

Query: 161 LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI-----GQSRII 215
             GAE+L+ P+A+     ++ HW TL  A A+    Y++A+ + G  N      G++   
Sbjct: 224 RLGAEVLLFPSAFTVKTGRD-HWGTLCRATAIQYQSYLIASAQYGAHNSKRTSWGETLAF 282

Query: 216 DPFGVTIA---AASEMPA--------------------LIMAEVTPERVRQVRAQLPVLN 252
           DP+G  +    +  + P                       + E+   +V++ R Q+P+  
Sbjct: 283 DPWGRQLGRLRSVDDTPPPKEGEEGDKGVEKLYEDSGEFFLCEIDGTKVKETRGQIPLAI 342

Query: 253 NRR 255
            +R
Sbjct: 343 QKR 345


>UniRef50_C0D6C3 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D6C3_9CLOT
          Length = 289

 Score = 89.0 bits (219), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 68/250 (27%), Positives = 107/250 (42%), Gaps = 22/250 (8%)

Query: 16  KNAEICASLMAQAAENDASLFALPE-----ALLARDDHDADLSVKSAQLLEGEFLGRLRR 70
           KN       + +AA+  A    LPE      LL   D +    V   + L          
Sbjct: 34  KNVAAARDFIRKAADKGAEWAVLPELFQTGYLLGGRDREYAGPVPGGEAL------CWME 87

Query: 71  ESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNE 130
           E+ R     +    +    G+ ++  V +    ++  Y K+HL+      E  R   GN+
Sbjct: 88  ETAREFGIMLTGGIIEEQGGKLYDTAVTVSQHGLLGAYRKIHLWGG----EKERFTPGND 143

Query: 131 IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAAR 190
               ++    K+G+  CY+  FPE A  Q L+GA  L   AA+  G  +   W     AR
Sbjct: 144 TGTPMDCGNWKIGMQICYEAGFPEGARLQVLKGANALAYVAAF--GAARAEVWDLATRAR 201

Query: 191 ALDTTCYMVAAGE-----CGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVR 245
           AL+  CY++A+       CG K  G+SRI+ P G  +A   E   + +A++    ++Q R
Sbjct: 202 ALENGCYVLASDRCGTEPCGTKFAGRSRIVAPDGTILAQVEEGEGIAVAKLELSNIQQQR 261

Query: 246 AQLPVLNNRR 255
           A LP L + R
Sbjct: 262 AVLPYLKDLR 271


>UniRef50_Q724C2 Hydrolase, carbon-nitrogen family n=20 Tax=Bacilli
           RepID=Q724C2_LISMF
          Length = 259

 Score = 89.0 bits (219), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 68/241 (28%), Positives = 115/241 (47%), Gaps = 22/241 (9%)

Query: 25  MAQAAENDASLFALPEAL-----LARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTT 79
           + +AA+N A +  LPE       L      ADL+ +  +    EFL  L  + +  ++  
Sbjct: 27  IVEAAKNGADIAVLPEMWNTGYALNELAGVADLNGERTK----EFLATLSEKHQIAIIGG 82

Query: 80  ILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVE 138
            ++I   S   +  N + A  + G +++ Y K+HL+    + E   ++AGN+   L  ++
Sbjct: 83  SVSI---SEGTKFSNTMYAFDKYGGLLSSYKKVHLFQL--MNEHLYLEAGND-TNLFRLD 136

Query: 139 GMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYM 198
           G+      CYD+RFPE       +G+E++ + A W    + +  W  LL ARA++   ++
Sbjct: 137 GVSCAGFICYDIRFPEWIRKHTSEGSEVIFVSAQWPAERVTQ--WEQLLIARAIENQAFV 194

Query: 199 VAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
           VA    G    N   G S +IDP G  +A   E    I AE+  + V + R  +PV  +R
Sbjct: 195 VAVNRVGDDPNNHFNGHSLVIDPLGNIVAHGGEDEGNIYAEIDLKLVAETRGIIPVFTDR 254

Query: 255 R 255
           R
Sbjct: 255 R 255


>UniRef50_A1SE99 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=14 Tax=Actinomycetales RepID=A1SE99_NOCSJ
          Length = 280

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 58/173 (33%), Positives = 89/173 (51%), Gaps = 13/173 (7%)

Query: 93  WNMLVALQ-AGNIVARYAKLHLYDAFAIQESRRVDAGNE--IAPLLEVEG-MKVGLMTCY 148
           WN  V +   G +   Y K+H +  F   E R ++AG +  +A L+   G  +VG+ TCY
Sbjct: 112 WNTSVLISPQGTVHKTYRKIHRF-GFGDGEPRVLEAGTDLAVAELVHDTGASRVGMATCY 170

Query: 149 DLRFPELALAQALQGAEILVLPAAWVRGPLKE-HHWSTLLAARALDTTCYMVAAGECGNK 207
           DLRFPEL       GA+++VLPAAW   P++   HW  L  ARAL+   +++     G  
Sbjct: 171 DLRFPELFRRLGDLGADVIVLPAAW---PMRRVEHWRLLGRARALENQAWVLQCNTAGTH 227

Query: 208 N----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           +     G S+++ P G  +A       +++ ++    V  VRA  PVL +RR 
Sbjct: 228 SGLDMGGHSQVVAPTGEVVAELGSDEDVLLTDIDLNLVASVRADFPVLADRRI 280


>UniRef50_D0XIR2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Alphaproteobacteria RepID=D0XIR2_9CAUL
          Length = 282

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 81/260 (31%), Positives = 121/260 (46%), Gaps = 33/260 (12%)

Query: 24  LMAQAAENDASLFALPEAL-----------LARDDHDADLSVKSAQLLEGEFLGRLRRES 72
           L+ QAA+  A L   PE             LA  D D D +V   + L  E    L    
Sbjct: 28  LIRQAADGGAKLILTPEGTNLLEQRRDRRGLAVTDEDQDAAVIGLRHLAAELGVWL---- 83

Query: 73  KRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-----AFAIQESRRVD 126
              ++ + +     +   RA N  + + A G IVARY KLH++D         +ES  + 
Sbjct: 84  ---LIGSAIVKSGHAGDDRAANRSLLIDANGTIVARYDKLHVFDVDLANGETYRESSTIR 140

Query: 127 AGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTL 186
            G+  A +      ++GL  CYD+RFP L    A  GA ++ +PAA+   P  E HW TL
Sbjct: 141 PGDG-ACVAGTPWGRMGLTICYDVRFPHLFRQLARAGACMIAVPAAFTV-PTGEAHWETL 198

Query: 187 LAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTIAAAS-EMPALIMAEVTPER 240
           L ARA++T  +++A       E G +  G S ++ P+G  IA    + P ++ A +    
Sbjct: 199 LRARAIETGAFVLAPAQGGTHEDGRRTWGHSIVVGPWGEVIAKLDHDEPGVLHATLDLAA 258

Query: 241 VRQVRAQLPVL-NNRRFAPP 259
           V   R  +P L ++R FAPP
Sbjct: 259 VEAARTSVPQLRHDRDFAPP 278


>UniRef50_B1I274 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Candidatus Desulforudis audaxviator MP104C
           RepID=B1I274_DESAP
          Length = 272

 Score = 88.2 bits (217), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 74/257 (28%), Positives = 120/257 (46%), Gaps = 18/257 (7%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLG 66
           Q  VT+  E+N      + A+AA   A +  LPE       H+     + A+        
Sbjct: 10  QMPVTASKEQNLSRARQMAAEAARAGARVVVLPEMFNCPYQHE--FFTRFAETCPDGDTF 67

Query: 67  RLRRESKRNMMTTILTIHVP-STPGRAWNM-LVALQAGNIVARYAKLHLY----DAFAIQ 120
           R+   + R +   ++   +P +  GR +N   V    G ++ R  KLHL+    D    +
Sbjct: 68  RMLTSTARELGVYLIGGSIPEAEDGRTYNTCFVYGPDGRMLGRQRKLHLFNIETDDLVFR 127

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--VRGPL 178
           ES  +  G     +     +  G+  C+DLRFPEL    A +GAE++V PAA+    GP 
Sbjct: 128 ESDTLSPGTGPPTVFVTPLVTFGVAICFDLRFPELFRDLAARGAELIVAPAAFNTFTGP- 186

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPALIM 233
              HW  LL ARA+D   ++  AG    ++      G S +++P+   IA A E   +++
Sbjct: 187 --PHWELLLRARAVDNQVFVAGAGPAWTEDSPYPYYGHSLVVNPWAEVIACAGERETVLL 244

Query: 234 AEVTPERVRQVRAQLPV 250
           AE+   +V +VR +LP+
Sbjct: 245 AEIDLGQVAEVRKKLPL 261


>UniRef50_Q5DC61 SJCHGC06938 protein n=1 Tax=Schistosoma japonicum
           RepID=Q5DC61_SCHJA
          Length = 290

 Score = 88.2 bits (217), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 62/189 (32%), Positives = 91/189 (48%), Gaps = 25/189 (13%)

Query: 90  GRAWNMLVALQA-GNIVARYAKLHLYD-----AFAIQESRRVDAGNEI----APLLEVEG 139
           G+ +N        G +V  Y KLHL+D      F  +ES  + +G E      PL   E 
Sbjct: 92  GKIYNCCATYNPDGELVGLYRKLHLFDIDIPGQFTFKESASLSSGKETFSFEMPLKSSEN 151

Query: 140 ----MKVGLMTCYDLRFPELALAQALQ-GAEILVLPAAW--VRGPLKEHHWSTLLAARAL 192
               ++VG+  CYD+RFPEL+L  A Q G ++L+ PAA+    G L   HW  L  ARAL
Sbjct: 152 KISVIRVGIGICYDIRFPELSLLYANQLGCQLLLFPAAFNPKTGSL---HWELLGRARAL 208

Query: 193 DTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQ 247
           DT CY+       N  +      +S I  P+G+ IA   +   ++ A +    ++ VR  
Sbjct: 209 DTQCYVGMCSPACNLELDYISYAESLITSPWGMVIAKGGKEEEILTANLDFSELKHVRES 268

Query: 248 LPVLNNRRF 256
           +P+   RR 
Sbjct: 269 IPIGRQRRL 277


>UniRef50_A1WYY7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Proteobacteria RepID=A1WYY7_HALHL
          Length = 286

 Score = 88.2 bits (217), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 57/166 (34%), Positives = 89/166 (53%), Gaps = 14/166 (8%)

Query: 102 GNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLL-EVEGMKVGLMTCYDLRFPEL 155
           G  +A Y K+HL+D       A +ES     G    PL+ +    ++G+  CYDLRFPEL
Sbjct: 124 GGRLACYDKIHLFDVEVAPGEAYRESNTQQPG--ATPLVVDTPVGRLGVAVCYDLRFPEL 181

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIG 210
               A QGAEI+ +P+A+      E HWS L+ ARA++   YMVA  +      G +  G
Sbjct: 182 FRELADQGAEIVAVPSAFT-AVTGEAHWSILVRARAIENLFYMVAPNQGGYHVNGRETHG 240

Query: 211 QSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           +S ++DP+G  + +      +I  EV+  R+ ++R + P L +R+ 
Sbjct: 241 ESMVVDPWGRVMKSLERGAGVITVEVSLSRLHEIRERFPALLHRKL 286


>UniRef50_A8MC40 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8MC40_CALMQ
          Length = 279

 Score = 88.2 bits (217), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 61/210 (29%), Positives = 99/210 (47%), Gaps = 10/210 (4%)

Query: 51  DLSVKSAQLLEGEFLGRLRRESKRNMMTTILTI-HVPSTPGRAWNMLVALQAGNIVARYA 109
           DL ++ A+ L+G+ +G L   ++    T I  I       G  +N  VA+    ++A Y 
Sbjct: 53  DLLLQIAEPLDGKSIGELTEIAREGKCTIITGIAERDKDTGVVYNSAVAIGENGLMALYR 112

Query: 110 KLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
           K HL       ESR    G   AP+  + G K GL  CYD  +PE++ +  L+GA + V 
Sbjct: 113 KRHLPSYGVFDESRYFGVGRGDAPVFSMNGTKAGLAICYDAFYPEVSRSLMLKGARVQVY 172

Query: 170 PAAWVRGP-LKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAA 224
            +A    P +   H+ T + ARA++   +++     G  +     G S I+DP G  +A 
Sbjct: 173 ISA---APDMSRPHFETFIRARAMENVSFVIYVNTIGQYDGLGFFGGSFIVDPLGEVVAK 229

Query: 225 ASEMPA-LIMAEVTPERVRQVRAQLPVLNN 253
           A       ++AE+ P  V   R+  P+L +
Sbjct: 230 AKYYEEDTVVAEIDPGLVDNYRSIRPILKD 259


>UniRef50_A1HQ26 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HQ26_9FIRM
          Length = 258

 Score = 87.4 bits (215), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 67/209 (32%), Positives = 98/209 (46%), Gaps = 16/209 (7%)

Query: 55  KSAQLLEGEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQA-GNIVARYAKLH 112
           K A+ +EG  +  +   S R     I+   +P    G+ +N  V +   GN+ A Y K+H
Sbjct: 53  KWAEDVEGLTISEMSNIS-RKYGAYIIAGSIPLRKNGKVYNGAVVIGPDGNVAAEYRKIH 111

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
           L   F++    R  A  +      ++G+  G+  CYDLRFPEL    AL GA+I+ LPA 
Sbjct: 112 L---FSMMGEERFFAAGDRRCTFNLKGVTAGIAICYDLRFPELFRVLALDGAQIVFLPAE 168

Query: 173 W--VRGPLKEHHWSTLLAARALDTT---CYMVAAGEC-GNKNIGQSRIIDPFGVTIAAAS 226
           W   RG     HW  L   RA++     C +   GE  GN   G S +I P G  +A   
Sbjct: 169 WPTARG----EHWHLLSRTRAIENQVFLCVVNCVGEHKGNPFYGHSMLIGPSGEVLAEGG 224

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           E   ++ AE     V + R ++ V  +RR
Sbjct: 225 EEETILYAEADFALVAKAREKMSVWQDRR 253


>UniRef50_C4XZI3 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
           42720 RepID=C4XZI3_CLAL4
          Length = 344

 Score = 87.4 bits (215), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 65/211 (30%), Positives = 99/211 (46%), Gaps = 19/211 (9%)

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYD----- 115
           GE    L + +KR+ +  +      S   + +N  +    +G+I+A++ K HL+D     
Sbjct: 122 GETTKFLAQLAKRHGVFIVGGSFPESDQDKIYNTSLTFSPSGDIIAKHRKAHLFDIDIPN 181

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALA--QALQGAEILVLPAAW 173
               +ES  + AG++       +   VGL  CYD+RFPELA+A  +A   A  +  P A+
Sbjct: 182 GITFKESITLSAGDKATVFGLGDFGTVGLGICYDIRFPELAMAASRAPHNAFAMFYPGAF 241

Query: 174 --VRGPLKEHHWSTLLAARALDTTCYMV------AAGECGNKNIGQSRIIDPFGVTIAAA 225
               GPL   HW  L  ARA+D   + V        G  G +  G S ++DP G  IA A
Sbjct: 242 NTTTGPL---HWHLLARARAVDNEVFTVLCSPARDVGGSGYQAYGHSLVVDPSGKIIAEA 298

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            E   ++ AE+    +   R  +PV   RRF
Sbjct: 299 GEGEEILYAELDHSLLPSARTGIPVHYQRRF 329


>UniRef50_A0BLB1 Chromosome undetermined scaffold_114, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0BLB1_PARTE
          Length = 284

 Score = 87.0 bits (214), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 55/181 (30%), Positives = 84/181 (46%), Gaps = 19/181 (10%)

Query: 90  GRAWNMLVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGL 144
           G+ +N  +A   G +V +Y K HL+D          ES    +GN+   + + +  + GL
Sbjct: 97  GKLFNAALAFNDGKLVGQYRKCHLFDVDIPGGITHFESNTFGSGNDYC-IFDSQYGRYGL 155

Query: 145 MTCYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAG 202
             CYD+RFP  +     QG ++L  P+A+    GPL   HW  L  +RALD   Y+ +A 
Sbjct: 156 GICYDIRFPIYSQVMRDQGCQVLSFPSAFNQTTGPL---HWELLNRSRALDNQVYVASAQ 212

Query: 203 EC--------GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
                       +  G S I DP G  +A     PA+++ E+    V QVR  +P    +
Sbjct: 213 AARYYSDDPDYYQTWGHSIITDPMGRVLATCESDPAVLIQEINLSLVDQVRKNIPTSVQK 272

Query: 255 R 255
           R
Sbjct: 273 R 273


>UniRef50_C4QU15 Nitrilase-related (Fragment) n=2 Tax=Schistosoma mansoni
           RepID=C4QU15_SCHMA
          Length = 353

 Score = 87.0 bits (214), Expect = 5e-16,   Method: Compositional matrix adjust.
 Identities = 56/157 (35%), Positives = 84/157 (53%), Gaps = 23/157 (14%)

Query: 121 ESRRVDAGNEIAPLLEVEGMKVG---LMTCYDLRFPELALA-QALQGAEILVLPAAWVRG 176
           ES+ + AG E AP++ ++   VG   L  CYD+RFPELA   +  + A +L  P+A+   
Sbjct: 59  ESKTIRAGTE-APIV-IQNTPVGNLGLAICYDMRFPELASHLRYAKNAHVLSYPSAYTTR 116

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE-MPA 230
             +  HW TL+ ARA++  CY+VAA + G  N      G S ++DP+G  IA  +   P 
Sbjct: 117 TGEAGHWHTLIRARAIENQCYVVAAAQEGKHNEGRSSYGHSLVVDPWGQIIAEQTNPGPG 176

Query: 231 LIMAEVTP-----------ERVRQVRAQLPVLNNRRF 256
           L+  E+ P            ++ QVR  +PV  +RRF
Sbjct: 177 LLTCEIGPFTMINSTTSIIPKIYQVRRSMPVEYHRRF 213


>UniRef50_A0JTY0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Arthrobacter RepID=A0JTY0_ARTS2
          Length = 292

 Score = 87.0 bits (214), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 62/190 (32%), Positives = 96/190 (50%), Gaps = 12/190 (6%)

Query: 72  SKRNMMTTILTIHVPSTPGRAWNMLVAL--QAGNIVARYAKLHLYDAFAIQESRRVDAGN 129
           ++RN +  + ++   +  GR W +   L    G  +  YAK+HL   F  +E +     +
Sbjct: 73  ARRNGIALVYSLPAITADGR-WQITATLVDHEGTELLNYAKVHL---FGAEERKAFSPAS 128

Query: 130 EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAA 189
           E   +++  G+K  ++ CYD+ FPE   A A +GAE+L++P A  +G   +     LL A
Sbjct: 129 EPPAVVDFHGIKTSMVICYDVEFPEAVRAAATRGAELLLVPTALAQG--FDSVPQILLRA 186

Query: 190 RALD---TTCYMVAAG-ECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVR 245
           RAL+   T  Y   AG E G + +G S I  P G  +AAA   P L+ A+V+    R  R
Sbjct: 187 RALESQLTVAYANHAGEEDGCEFLGGSVIAGPDGSLLAAAGPAPELLFAKVSAASARDAR 246

Query: 246 AQLPVLNNRR 255
             +P L  RR
Sbjct: 247 EGVPYLRERR 256


>UniRef50_Q2BKP4 Putative carbon-nitrogen hydrolase n=1 Tax=Neptuniibacter
           caesariensis RepID=Q2BKP4_9GAMM
          Length = 276

 Score = 87.0 bits (214), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 60/168 (35%), Positives = 87/168 (51%), Gaps = 20/168 (11%)

Query: 102 GNIVARYAKLHLYDA------FAIQESRRVDAGNEIAPLLEVEGMKVG---LMTCYDLRF 152
           G + A Y K+HL+D        A +ES     G E+     VE   VG   L  CYDLRF
Sbjct: 109 GELKAHYDKVHLFDVDVEDKHAAYRESDYFTPGKELV----VEQTSVGCFGLSICYDLRF 164

Query: 153 PELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----K 207
           PE     A  GA I+++P+A+     K  HW  LL ARA++T  Y++AA + G       
Sbjct: 165 PEHYQRLADMGANIMLVPSAFTAVTGKA-HWEVLLRARAIETQSYVIAANQAGKHTASRS 223

Query: 208 NIGQSRIIDPFGVTIAAA-SEMPALIMAEVTPERVRQVRAQLPVLNNR 254
           + G S I+DP+G  +A   ++ P L +A++  + VR  R  +PV  +R
Sbjct: 224 SWGHSMIVDPWGKVLAECHNDGPGLAVADIDLQEVRNRRKAMPVTLHR 271


>UniRef50_A0LH50 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Syntrophobacter fumaroxidans MPOB
           RepID=A0LH50_SYNFM
          Length = 260

 Score = 86.7 bits (213), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 11/197 (5%)

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQE 121
           E +  +R  ++R+ M  + ++   S  GR +N    + A G I   Y K+HL   F++  
Sbjct: 64  EVVEEMRGWARRHGMVLVGSLP-ESVDGRIYNTSYVIDANGEIAGSYRKVHL---FSLHH 119

Query: 122 SRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEH 181
                   E + +   E  ++G+M CYDLRFPEL    AL GA I+ + + W    ++  
Sbjct: 120 EDLHFGRGETSLVCSTEAGELGVMICYDLRFPELGRKLALDGARIMCVSSHWP--DIRID 177

Query: 182 HWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALIMAEVT 237
           HWS LL ARA++   +++    CG +      G S II P G  +  A   P  I A + 
Sbjct: 178 HWSLLLRARAVENQLFVIGCNGCGTEKKMRYGGASAIISPMGKVLIEAGTGPESIAAALD 237

Query: 238 PERVRQVRAQLPVLNNR 254
            E V + R  +    +R
Sbjct: 238 MEEVDRFRKLITCFPDR 254


>UniRef50_C7GZE3 Nitrilase protein n=1 Tax=Eubacterium saphenum ATCC 49989
           RepID=C7GZE3_9FIRM
          Length = 268

 Score = 86.7 bits (213), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 52/186 (27%), Positives = 92/186 (49%), Gaps = 16/186 (8%)

Query: 82  TIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD----AFAIQESRRVDAGNEIAPLLE 136
           +I      G  +N   V  + G+ +AR+ K+HL+D        +ES  +  G   A +++
Sbjct: 82  SIPFKDEKGDIYNTSFVFSKDGDEIARHDKIHLFDIDFEDMHFKESLFLKNGT-TATVVD 140

Query: 137 VEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV--RGPLKEHHWSTLLAARALDT 194
            E  K+G+  C+D+RFPEL  A   +GA+++++P ++    GPL   HW   L  RA+D 
Sbjct: 141 TEFGKIGIGLCFDVRFPELFRAMTNRGAKLILVPGSFNMRTGPL---HWENTLKQRAVDN 197

Query: 195 TCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLP 249
             ++       ++N        S  +DP G+++    E    I+ E+    V++ R  LP
Sbjct: 198 QIFIAGCSPARDENAIYVSFANSMAVDPLGISLGNCGEEEGCIVEEIDFREVKRARNVLP 257

Query: 250 VLNNRR 255
           +L N +
Sbjct: 258 ILKNYK 263


>UniRef50_A6TPX2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Clostridia RepID=A6TPX2_ALKMQ
          Length = 269

 Score = 86.7 bits (213), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 45/142 (31%), Positives = 76/142 (53%), Gaps = 5/142 (3%)

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +E +  + GN   P+ + +  KVG++ CY++ FPE +   ALQG E++V P+ W      
Sbjct: 119 REQQIFEEGNIEYPVFDTKIGKVGILICYEMEFPETSRLLALQGVEMIVCPSVWSLS--A 176

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASE-MPALIMAEVTP 238
            H W   L ARALD T Y+      GN + G+S+++ P G  +A AS+    L++  +  
Sbjct: 177 SHRWDIQLPARALDNTVYVFGVNTVGNNSCGKSKLVSPLGDVLAEASDRKEELLIRAIDK 236

Query: 239 ERVRQVRAQLPVLNN--RRFAP 258
           E +   R  +P L++  ++  P
Sbjct: 237 EALDWARETVPYLHDYEKKLTP 258


>UniRef50_Q2G6S2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Sphingomonadales RepID=Q2G6S2_NOVAD
          Length = 281

 Score = 86.7 bits (213), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 55/167 (32%), Positives = 87/167 (52%), Gaps = 12/167 (7%)

Query: 102 GNIVARYAKLHLYDA-FAIQESRRVDA----GNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G + ARY K+H++D   A  E+ R  A    G ++  +    GM +G+  CYD+RFP L 
Sbjct: 113 GAVAARYDKIHMFDVDLATGETWRESAAYTPGEQVVTVETPVGM-LGMAICYDVRFPALF 171

Query: 157 LAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQ 211
                +  + + +PAA+   P  + HW  +  ARA++ + +++AA      E G +  G 
Sbjct: 172 EELGRRRCDAIRIPAAFTV-PTGKAHWHLMQRARAVEASAWVIAAAQGGRHEDGRETFGH 230

Query: 212 SRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
           S ++DP+G       E  +L  A + P R  +VRAQLP L N+R  P
Sbjct: 231 SLVVDPWGEVALDGGEGTSLGYAVIDPARTDEVRAQLPSLANKREIP 277


>UniRef50_C2D0V8 Possible N-carbamoylputrescine amidase n=1 Tax=Lactobacillus brevis
           subsp. gravesensis ATCC 27305 RepID=C2D0V8_LACBR
          Length = 291

 Score = 86.3 bits (212), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 61/198 (30%), Positives = 98/198 (49%), Gaps = 17/198 (8%)

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTI--HVPSTPGRAWN--MLVALQAGNIVARYAKLH 112
           A+ + G+ +  ++  +KR  +  I        +  G  +N  ML+  Q G IV  Y K+H
Sbjct: 61  AETVTGQSVQYMQNVAKRYHVYLIFGFAQRDQTNAGTIYNSTMLINDQ-GQIVGTYQKVH 119

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
           L+D     E R    G +  P+ + +   +G+M CYD  FPE+A   AL+ A++L +   
Sbjct: 120 LFDT----EQRYFTPG-KTYPVFKTKIGTIGMMICYDTFFPEVARILALEHADLLTISTN 174

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAA-ASE 227
           W R  +++  W   + ARALD    +VAA   G        G S+IIDP G  +++  SE
Sbjct: 175 WERPRIQD--WELCVRARALDNIIPIVAANRIGFDKELDFFGHSKIIDPLGTVMSSLDSE 232

Query: 228 MPALIMAEVTPERVRQVR 245
            P  + A +  E+ R +R
Sbjct: 233 RPGYLQATIDYEQTRGLR 250


>UniRef50_A8UWC0 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=A8UWC0_9AQUI
          Length = 248

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 69/252 (27%), Positives = 119/252 (47%), Gaps = 15/252 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q ++T   E N    A  + +  E   SL  LPE      D+D    ++   LL  
Sbjct: 5   LATIQLSLTDHVELNYNKLARFLDELEE--GSLVLLPEMFFCGFDYD---RLEEFALLSE 59

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQES 122
             + +L+  S++  +    T+   +  G   N    ++ G ++ R +K+ L+  F  +E 
Sbjct: 60  YIIEKLKLTSRQKNLLICGTVPEHTEEGIK-NTAFLIEDGKVIGRRSKVKLFYPF--EED 116

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
           R    G E  P+ + +  +VG++ C++LRF ++ L    +G +IL++PA W  G  +  H
Sbjct: 117 RYFVPGEE-NPVFKTKFGRVGILICFELRFTDMVLDLKKKGIDILLVPAQW--GYARREH 173

Query: 183 WSTLLAARALDTTCYMVAA---GEC-GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
              L  ARA++   Y+V +   GE  G K  GQS I  P+G  +  +      + AE   
Sbjct: 174 LRVLSQARAIELQSYVVVSDTWGEFKGTKFAGQSGIYSPWGEVLEFSETGDIYLEAEADL 233

Query: 239 ERVRQVRAQLPV 250
             V +VR+ +PV
Sbjct: 234 SYVEEVRSAIPV 245


>UniRef50_A4S5E0 Predicted protein n=2 Tax=Ostreococcus RepID=A4S5E0_OSTLU
          Length = 282

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 57/180 (31%), Positives = 96/180 (53%), Gaps = 20/180 (11%)

Query: 94  NMLVALQAGNIVAR-YAKLHLYDAFA--------IQESRRVDAGNEIAPLLEVEGMKVGL 144
           ++++  ++G I    Y K+HL+D  A        ++ES    AG  +A      G KVG 
Sbjct: 99  HVMIDPRSGEISGDVYRKIHLFDTDAAVGVDGGGMRESDYTRAGTTLASYDTTFG-KVGA 157

Query: 145 MTCYDLRFPELALAQALQG-AEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGE 203
             CYDLRFP++  A   +  A+++ +P+A+ +    + HW  LL ARA++T CY+VAA +
Sbjct: 158 SICYDLRFPDVYQALRFEHEADVICVPSAFTK-STGQAHWEVLLRARAIETQCYVVAAAQ 216

Query: 204 CGN-----KNIGQSRIIDPFGVTIAA---ASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            G      ++ G + +IDP+G  +A     S    + +AE+    V  +R Q+P+  +RR
Sbjct: 217 AGKHGETRESYGHAMVIDPWGRIVAKMDDPSNEVGIAVAEIDLALVDSIRTQMPLAEHRR 276


>UniRef50_C1E770 Predicted protein (Fragment) n=1 Tax=Micromonas sp. RCC299
           RepID=C1E770_9CHLO
          Length = 316

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 54/166 (32%), Positives = 86/166 (51%), Gaps = 16/166 (9%)

Query: 102 GNIVARYAKLHLYDA-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G ++ ++ K HL+D       + +ES  +  G E+  +++    ++G+  C+D+RFPELA
Sbjct: 144 GCLLGKHRKTHLFDVDIPGEISFKESDVLSPGTELT-VVDTAVGRLGIGICFDVRFPELA 202

Query: 157 LAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDT-----TCYMVAAGECGNKNI 209
           +A A +GA+I+V P A+  V GPL   HW  L  ARA+D      TC        G +  
Sbjct: 203 MACANRGAQIMVYPGAFNTVTGPL---HWELLQRARAVDNQMFVLTCSPSRVPGAGYQAW 259

Query: 210 GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G S  + P+   IA   E P  +  E+  E++R  R  +P+   RR
Sbjct: 260 GHSTAVGPWAEVIATTDEKPGTVHCELDMEQIRVRRRNMPLEKQRR 305


>UniRef50_Q1YU23 Hydrolase, carbon-nitrogen family protein n=1 Tax=gamma
           proteobacterium HTCC2207 RepID=Q1YU23_9GAMM
          Length = 281

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 79/281 (28%), Positives = 136/281 (48%), Gaps = 31/281 (11%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQ 58
            + AA Q       ++N     +L+ QAAE  + L  LPE  A L R D      V  A+
Sbjct: 7   FIAAAVQLRPQQSLQQNLAAAGALIEQAAEAGSRLVVLPENFAYLGRKDL---TEVGLAE 63

Query: 59  LLEGEFLGRLRRESKRNMM-----TTILTIHVPSTP-GRAWNMLVALQAGNIVARYAKLH 112
              G     L ++++R+ +     T  ++    S P  R+W  L   Q G++V  Y K+H
Sbjct: 64  QSTGPAYEFLAKQAQRHSLWLVGGTVPVSDANLSRPFARSW--LFDPQ-GDLVQHYDKIH 120

Query: 113 LYDAFA-------IQES--RRVDAGNEIAPLL--EVEGMKVGLMTCYDLRFPELALAQAL 161
           L+D          +Q++  R  D     A ++  E +  ++G+  CYDLRF EL    A 
Sbjct: 121 LFDVDVPTSKEGILQQATYRESDDYRSAATVVVAETDPCRLGMSVCYDLRFAELFRQLAD 180

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIID 216
             A+++ +PAA+     ++H W  LL ARA++   +++ A      +      G S I+D
Sbjct: 181 ADAQVVAVPAAFTAATGRDH-WELLLRARAVENQLFVIGANMVDRDHPRRGLWGGSAIVD 239

Query: 217 PFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
           P+G  +A   +   + +AE+  +R+ ++RA++PV  +R+ A
Sbjct: 240 PWGNVLARVDDEAGVAIAEINLDRLDEIRAKMPVAQHRKLA 280


>UniRef50_UPI000174507F Amidohydrolase n=1 Tax=Verrucomicrobium spinosum DSM 4136
           RepID=UPI000174507F
          Length = 258

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 67/230 (29%), Positives = 103/230 (44%), Gaps = 15/230 (6%)

Query: 33  ASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRA 92
            SL  LPE        +  ++ ++    +  FL  +  +    +M  +++   P   G+A
Sbjct: 38  GSLLVLPEMFSTGFSMNVAVTAQTEAREDEAFLSGVAMKHHCAVMGGVVS---PLVEGKA 94

Query: 93  WNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLR 151
            N  V     G ++ARYAK  L   F +          E      ++G  V    CYDLR
Sbjct: 95  QNESVTFGPDGELLARYAKQQL---FCLGGEADCHTPGEAVIAFPLQGFMVAPFVCYDLR 151

Query: 152 FPELALAQALQGAEILVLPAAWVRGPLKE-HHWSTLLAARALDTTCYMVAAGECGN---- 206
           FPEL    A+ GA +LV+ A+W   P+K  HHW TLL ARA++   YMV     G+    
Sbjct: 152 FPELFRDAAMVGANLLVVIASW---PVKRYHHWLTLLQARAIENQAYMVGVNRAGSDPHL 208

Query: 207 KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
              G+S ++ P G  I  A E    + A +    +++ R   P L + R+
Sbjct: 209 HYNGRSVVVSPHGHIITDAGESAGSVSARLDLADLQEWREVFPALRDSRW 258


>UniRef50_Q1MYM0 Predicted amidohydrolase n=1 Tax=Bermanella marisrubri
           RepID=Q1MYM0_9GAMM
          Length = 274

 Score = 85.5 bits (210), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 52/167 (31%), Positives = 88/167 (52%), Gaps = 14/167 (8%)

Query: 102 GNIVARYAKLHLYDAFA------IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
           G+ V +Y K+HL+D          +ES    AG + +  + ++G   GL  CYDLRFPEL
Sbjct: 110 GSEVCQYDKVHLFDVDVSDNKGRYRESDTFIAGTQ-SKTVSLDGTLYGLSVCYDLRFPEL 168

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI-----G 210
                 Q  +++ +P+A+      + HW TLL ARA++T  +++AA + G         G
Sbjct: 169 YQQYQKQSCQVVTVPSAFTY-TTGQKHWLTLLKARAIETQSFVMAANQVGTHEDGRITWG 227

Query: 211 QSRIIDPFGVTIAA-ASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           QS +I+P G  +    SE    ++ E+  E  +++R  +P+L ++R 
Sbjct: 228 QSIVINPDGEIVGELDSEKAGELVVELDLELCQKIRQSMPLLKHKRL 274


>UniRef50_UPI0000E105FE putative hydrolase, carbon-nitrogen family protein n=1
           Tax=Rhodobacterales bacterium HTCC2255
           RepID=UPI0000E105FE
          Length = 279

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 52/168 (30%), Positives = 87/168 (51%), Gaps = 14/168 (8%)

Query: 101 AGNIVARYAKLHLYDAF------AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPE 154
           +G +VA+Y K HL+D          QES     G+++  +L+ E  +VG+  CYD+RF  
Sbjct: 113 SGELVAQYNKTHLFDVSITDNTGTYQESATTMPGSDVV-VLDTEFGRVGICICYDIRFST 171

Query: 155 LALAQALQGA-EILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KN 208
           L  A   + A + LV+PAA+      + HW  LLA+RA++  CY++AA + G+       
Sbjct: 172 LFNAMVKENAIDYLVVPAAFTY-QTGQAHWHHLLASRAIEYQCYVIAANQGGSHCNGRHT 230

Query: 209 IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            G S I  P+G  +         ++A+  P R  +++  L V  +R++
Sbjct: 231 YGHSAIYSPWGDVLDMIENGAGFVIAKSDPNRHHEIKHALNVQQHRQY 278


>UniRef50_D2B8M8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Streptosporangium roseum DSM 43021
           RepID=D2B8M8_STRRD
          Length = 293

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 55/173 (31%), Positives = 84/173 (48%), Gaps = 15/173 (8%)

Query: 90  GRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCY 148
           G   NM V +   G ++A YAK HL+        RR  AG   A + +  G++  +M C+
Sbjct: 89  GGVGNMAVVVDDGGRVLASYAKAHLFGEI----DRRFHAGEAPAAVFDHHGVRCAVMICF 144

Query: 149 DLRFPELALAQALQGAEILVLPAAWVR--GPLKEHHWSTLLAARALDTTCYMVAAGECGN 206
           D  FPE     AL GA ++++P A +   G + EH    ++  RA +   ++     CG 
Sbjct: 145 DSEFPESVRVAALAGAHVVLVPTANMHPYGAINEH----VMWTRAWENKVHLAYVNRCGA 200

Query: 207 KN----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           +     +G+SRII P G  +AAA   P L+ A +  + V   RA    L+ RR
Sbjct: 201 EGRTAYVGRSRIIGPDGTELAAAGTGPDLVCATIDTDAVDSARAAFDYLSERR 253


>UniRef50_A9B254 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B254_HERA2
          Length = 259

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 54/158 (34%), Positives = 78/158 (49%), Gaps = 9/158 (5%)

Query: 102 GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL 161
           G  +  Y K HL     +QE R + AG + A + E          CYDLRFPEL    AL
Sbjct: 103 GKRLHSYRKTHLIGL--MQEDRYLAAGQQ-AEVFETAWGTSACAICYDLRFPELFRRYAL 159

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDP 217
            GA ++++PA W    ++  HW TLL ARA++    ++A    G    N+  G S +IDP
Sbjct: 160 AGAGVIIIPAEWPTARIE--HWRTLLRARAIENQAVVIACNRVGSDRANQFGGHSVVIDP 217

Query: 218 FGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           +G  +    +   L+ A V    + + R  LPV  +RR
Sbjct: 218 WGKVLVEGDDQAGLLTATVDLASIAKARDFLPVFRDRR 255


>UniRef50_A2FF61 Hydrolase NIT3, putative n=4 Tax=cellular organisms
           RepID=A2FF61_TRIVA
          Length = 273

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 70/275 (25%), Positives = 124/275 (45%), Gaps = 33/275 (12%)

Query: 2   LVAAGQFAVTSVWEKNAEIC--ASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           +V  G   ++S  +K A +   A  + + A++ A +  LPE          +    +A+ 
Sbjct: 1   MVKIGIVQLSSGDDKAANVARAAEKVKKCAQDGAEIVVLPEIF--------NGPYSTAKF 52

Query: 60  LE------GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLH 112
            E      GE   RL   +K N +  I          + +N   +  Q G  + ++ K+H
Sbjct: 53  REYSEPEGGETWQRLSNMAKENNIILIGGSISEFCEDKIYNTSYIFDQQGKQIGKHRKMH 112

Query: 113 LYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           ++D         +ES  +  GN++  +++    K+G+  C+D RFPELA   AL+GA+++
Sbjct: 113 MFDIDVKGGQRFKESDALTPGNQVT-VVDTSICKIGVCICFDFRFPELARLMALKGAKMI 171

Query: 168 VLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGV 220
           ++P A+    GP    HW  L   RA+D   + +      N      +   S ++ P+G 
Sbjct: 172 IVPGAFNMTTGPA---HWELLFRQRAVDNQVFTIGCAPARNTEASYVSFANSIVVGPWGD 228

Query: 221 TIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            I  A       + E+  E+V  +R QLP+L+ RR
Sbjct: 229 VIYNAGIEEKAEVVEIDLEKVDSIRQQLPLLSARR 263


>UniRef50_C5SMM5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Asticcacaulis excentricus CB 48
           RepID=C5SMM5_9CAUL
          Length = 280

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 59/167 (35%), Positives = 87/167 (52%), Gaps = 13/167 (7%)

Query: 100 QAGNIVARYAKLHLYDAFA-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPE 154
           + G  VA Y K+HL+DA        +ES  V  G E A +       +GL  CYD+RF  
Sbjct: 111 EMGEEVAFYDKIHLFDATTPNGEVYRESAGV-CGGERAVIAPTPWGGLGLTICYDVRFGY 169

Query: 155 LALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNI 209
           L  A A  GA ++ +PAA+   P  + HW  LL ARA++T C++ A  + G      K  
Sbjct: 170 LHRALAQGGASMIAVPAAFTV-PTGQAHWEVLLRARAIETGCFVFAPAQGGQHKDGRKTW 228

Query: 210 GQSRIIDPFGVTIAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G S II+P+G  ++    + PA++MAE+    V + R  +P L + R
Sbjct: 229 GHSMIINPWGEVMSRLDHDHPAVLMAEIDLSEVARARTAIPQLQHDR 275


>UniRef50_C7R9G8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7R9G8_KANKD
          Length = 273

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 48/169 (28%), Positives = 84/169 (49%), Gaps = 10/169 (5%)

Query: 97  VALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIA---PL-LEVEGMKVGLMTCYDLRF 152
           V  + G+++A Y K+HL+D    +     ++ N +A   P+    +G+  G   CYDLRF
Sbjct: 104 VYQEDGSLLAHYDKIHLFDVSVKEGESYSESSNTLAGSEPVTFNWQGITFGCSVCYDLRF 163

Query: 153 PELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----K 207
           PEL         ++++ P+A+     K  HW  LL ARA++   ++VA  + G      K
Sbjct: 164 PELYRYYQTHNVDVILAPSAFTLATGKV-HWKLLLQARAVENLAFVVAPNQTGTHDNQRK 222

Query: 208 NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             G S +IDP+G  I    E   + +A +   ++  ++ + PV  +R+ 
Sbjct: 223 TFGHSMVIDPWGEVIDELQEDEGISIATLNINKIDMIKEKFPVHLHRKL 271


>UniRef50_B8C1M9 Nitrilase n=1 Tax=Thalassiosira pseudonana RepID=B8C1M9_THAPS
          Length = 320

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 82/302 (27%), Positives = 131/302 (43%), Gaps = 62/302 (20%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE------ALLARDDH-------- 48
           VA  QF VT    +N       + +A ++ A L  LPE      A  A  D+        
Sbjct: 18  VALLQFHVTHDKPQNINTAREYILKARDSGAQLCVLPEIWNSPYATSAFGDYAEMLPSVG 77

Query: 49  ----DADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPST-PGRAWNM-LVALQAG 102
               D D    S+Q+L       +      NM   I+   +P T   + +N  LV    G
Sbjct: 78  DTFSDKDKWGPSSQML-------MELAQSTNMY--IVGGSIPETCSDKIFNTCLVVNPKG 128

Query: 103 NIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGM-------KVGLMTCYDL 150
            IV ++ K+HL+D         +ES  + AG E A   +V G        +VG+  CYD+
Sbjct: 129 TIVGKHRKVHLFDVNVPGGIQFKESETLSAG-EGATYFDVAGEDGDSGMGRVGVGICYDI 187

Query: 151 RFPELALA-QALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK 207
           RFPE AL    +   ++L+ P A+    GP    HW  L  ARA+D  C+++ A    + 
Sbjct: 188 RFPEYALLLTQIHKCKVLIYPGAFNLTTGPA---HWELLQRARAVDGQCFVLTASPARSN 244

Query: 208 N--------------IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN 253
                           G S ++ P+G  +A   E PA+++A++   +V ++R  +P ++ 
Sbjct: 245 PPLDDEQTKHPHYSAWGHSTVVSPWGEVVATCDEHPAVVVADLDMSKVEEMRMAIPTMSQ 304

Query: 254 RR 255
           +R
Sbjct: 305 KR 306


>UniRef50_C8PV21 Putative hydrolase Nit2 n=1 Tax=Enhydrobacter aerosaccus SK60
           RepID=C8PV21_9GAMM
          Length = 345

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 46/118 (38%), Positives = 68/118 (57%), Gaps = 8/118 (6%)

Query: 101 AGNIVARYAKLHLYDAFA------IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPE 154
           AG+ +ARY K+HL+ A          E R  +AGN +  + + E  K+G+M C+D+RFP 
Sbjct: 108 AGDCLARYDKIHLFKATVNDSTGNYDEGRTFEAGNALI-VADTEFGKIGMMVCFDIRFPT 166

Query: 155 LALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQS 212
           LA+     GA+IL  P+A+     K  HW  LL ARALD+ C ++ AG+ G+  +  S
Sbjct: 167 LAVKLRELGADILTAPSAFTYQTGKA-HWHALLTARALDSQCMVIGAGQTGDHVVNPS 223


>UniRef50_Q972X1 264aa long hypothetical beta-ureidopropionase n=1 Tax=Sulfolobus
           tokodaii RepID=Q972X1_SULTO
          Length = 264

 Score = 84.7 bits (208), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 65/254 (25%), Positives = 109/254 (42%), Gaps = 20/254 (7%)

Query: 14  WEK--NAEICASLMAQAAENDASLFALPE----ALLARDDHDADLSVKSAQLLEGEFLGR 67
           W+K  N E    L+ +A +N A + AL E         + +    S   A+   GE L R
Sbjct: 12  WDKKDNIERQVELVNKAIDNKAKIIALDELSNTIYFPFEQNPKYFS--WAETERGETLQR 69

Query: 68  LRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDA 127
            +  SK   ++ I+ I         +N    L  G I+ +Y K HL       E      
Sbjct: 70  FKEISKEREVSLIVPI-FERDSNFFYNTAFILDNGEIIGKYRKTHLPQEEFFNEYYYFKV 128

Query: 128 GNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLL 187
           G+   P+ +++G+K G++ C+D  FPE    + ++GA ++ +P+       KE  W   L
Sbjct: 129 GDLGFPIFDLKGVKTGVVICHDRHFPEPVRVEVIKGAWLIFIPSV---AAFKE-IWELEL 184

Query: 188 AARALDTTCYMVAAGECGN-------KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
            A A+  T Y+      G        +  G+S II P G  +  A +   ++ A+++ + 
Sbjct: 185 KAHAVFNTVYIAGINRFGKEYPNQKEEYFGESMIISPIGEIVTKAEKNEEILYADISEDE 244

Query: 241 VRQVRAQLPVLNNR 254
           V   R + P L  R
Sbjct: 245 VINARIKRPFLKKR 258


>UniRef50_C9XNA8 Putative carbon-nitrogen hydrolase n=6 Tax=Clostridium difficile
           RepID=C9XNA8_CLODC
          Length = 268

 Score = 84.7 bits (208), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 65/261 (24%), Positives = 121/261 (46%), Gaps = 21/261 (8%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL--EGEF 64
           Q +V    +KN E    ++    ++ A +  LPE      + ++   VK+ +L+    ++
Sbjct: 12  QHSVLGDVKKNIEKAVEMIDDLGKHGADIICLPELFATGYNLESLGGVKTLELIREHNKY 71

Query: 65  LGRLRRES-KRN---MMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAI 119
           +     E+ KRN   +++   T+   ST    +N  V   + G I+  Y K HL+   A+
Sbjct: 72  IEESMSEAAKRNNVYLISPYGTLEKGST--HVYNSAVIFDRKGKIMGEYCKNHLWSLEAV 129

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
                   G E   + + +  + G+M CYD  FPE++    L+G+EI+ +P+AW      
Sbjct: 130 YFK-----GGEKVEVYDADFGRFGVMICYDAGFPEVSRELTLKGSEIIFIPSAWR--IQD 182

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEM-PALIMA 234
           E  W   ++ RAL+ T Y V      N +     G+S+I +P G  I          +++
Sbjct: 183 EDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGKSKICNPRGTVITQLDTYREKYVLS 242

Query: 235 EVTPERVRQVRAQLPVLNNRR 255
           E+  + +++ R  +P L +R+
Sbjct: 243 EIDLDEIKKYREDIPYLKDRK 263


>UniRef50_A6DN63 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Lentisphaera araneosa HTCC2155
           RepID=A6DN63_9BACT
          Length = 292

 Score = 84.7 bits (208), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 65/259 (25%), Positives = 120/259 (46%), Gaps = 22/259 (8%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEA--LLARDDHDADLSVKSAQLLEGEF 64
           Q + +  +E+N     S++ QA++N   L   PE   L A+     D++ ++A+  E ++
Sbjct: 32  QMSSSPDFEENLAHAKSIIEQASQNRDELIIFPECALLWAK----TDITHQNAKTRE-QW 86

Query: 65  LGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF-----A 118
              L   SK   +  +          + +N      A G+++  Y K HL+  F     A
Sbjct: 87  TDLLSPLSKTYKIAIVWGGLAERQENKVFNSSFIFDADGHLLDVYRKTHLFQIFTPGKKA 146

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           I E+   + G+    ++++    +G+  CYDLRFPE     A  G ++++  AA+ +   
Sbjct: 147 IDETETYEHGDTGPCVVKINDWSIGISICYDLRFPEFLRNYA--GCDLMINSAAFTKATG 204

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNI------GQSRIIDPFGVTIAAASEMPALI 232
           K  HW  L+ ARA++   Y++ + +CG   +      G S +IDP+G  +    E  A  
Sbjct: 205 KA-HWEVLMRARAVENQSYVIGSAQCGRNELSGISAYGHSIVIDPWGEVLGDLGESIASQ 263

Query: 233 MAEVTPERVRQVRAQLPVL 251
              +  + ++Q R  +P L
Sbjct: 264 SFVLNKQIIQQTRETVPAL 282


>UniRef50_B7CB92 Putative uncharacterized protein n=1 Tax=Eubacterium biforme DSM
           3989 RepID=B7CB92_9FIRM
          Length = 262

 Score = 84.0 bits (206), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 66/233 (28%), Positives = 106/233 (45%), Gaps = 18/233 (7%)

Query: 32  DASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGR 91
           D  +  LPE       +DA   +K+A L   E L  L+  ++ N +  +      S    
Sbjct: 22  DCDILVLPEMWNCPYHNDA---LKTAYLRHDESLEALKETARTNKIWIV----AGSICTN 74

Query: 92  AWNMLVALQA-GNIVARYAKLHLYDAFAIQ---ESRRVDAGNEIAPLLEVEGMKVGLMTC 147
            +N    L + G+IV  Y K HL++    Q   E+     GN +    +    K G++ C
Sbjct: 75  KYNRCYILNSDGDIVCSYDKTHLFEFHNKQDYCENEVFVPGNHLQ-CFDTPWGKCGILLC 133

Query: 148 YDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYM--VAAGECG 205
           YD+RFPE++   A  GA+IL  PAA+     K+ HW      RAL+   ++  VA  +  
Sbjct: 134 YDIRFPEVSRILAQNGAQILFCPAAFNEQATKK-HWKLFTQTRALENEVFLCGVAPAKYT 192

Query: 206 NKNI---GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            KN    G S ++D FG  +    E  A  + ++  + + +VR ++P    RR
Sbjct: 193 YKNYTSGGHSILVDGFGNIVVELGEEEACKVVDIHLKDIEKVRKRMPYWKVRR 245


>UniRef50_D2RHR5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Archaeoglobus profundus DSM 5631
           RepID=D2RHR5_ARCPR
          Length = 231

 Score = 83.2 bits (204), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 47/169 (27%), Positives = 84/169 (49%), Gaps = 5/169 (2%)

Query: 85  VPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGL 144
           +   P + +N  + +  G I+ R+ K  L+    + E +   AG  + P+    G+  G+
Sbjct: 67  IAGIPEKGYNTALVIHRGKILGRHRKTKLFPL--LNEHKIFKAGKVVKPIETPFGL-FGI 123

Query: 145 MTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC 204
           M CY+LRFPE+A     +GA+IL + A +    ++  HW  LL ARA++   ++V     
Sbjct: 124 MICYELRFPEIARKLVNKGAKILFVIAQFPSERIE--HWKVLLRARAIENQVFVVGVNCV 181

Query: 205 GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN 253
            +   G S ++DP G  +    +  A    ++  + V +VR + P LN+
Sbjct: 182 NDHCGGYSMVVDPLGNVLKELGDCEAYDEVDINIKYVDEVRKKYPFLNS 230


>UniRef50_A8ZTL1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfococcus oleovorans Hxd3 RepID=A8ZTL1_DESOH
          Length = 272

 Score = 82.8 bits (203), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 66/238 (27%), Positives = 107/238 (44%), Gaps = 13/238 (5%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           ++N E  A  + +AA   A +   PE  ++    DA L  ++A     + +G L R +  
Sbjct: 19  DRNLETTARWVGKAAARGAGIVCFPELNVSGYCLDAALYREAAGRYN-DVVGALSRMATA 77

Query: 75  NMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPL 134
             +  +      +  GR     + +        Y KLH+    A  E +    G ++ PL
Sbjct: 78  FDIVILAGTVAEAAGGRVTACHLVISPNGSAGGYTKLHI----APPEKQLFVPGRKV-PL 132

Query: 135 LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEH--HWSTLLAARAL 192
            E +G   G+  CYD  FPEL+ A AL+GA+IL +P A  R   +E    W   L ARA 
Sbjct: 133 FEAKGAVFGVQLCYDAHFPELSTAMALKGADILFVPHASPRNTPEEKLASWMRHLPARAY 192

Query: 193 DTTCYMVAAGECGNKNIGQ-----SRIIDPFGVTIAAASEMPALIMAEVTPERVRQVR 245
           D   ++ A  + G    GQ     +  +DP G  +A  +   ++I+A+ +P  +  VR
Sbjct: 193 DNGVFVAACNQAGENGAGQGFPGVAVALDPSGKVMAQTTSPDSMIVADCSPSTLNTVR 250


>UniRef50_B2TQP4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Clostridium RepID=B2TQP4_CLOBB
          Length = 259

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 65/262 (24%), Positives = 116/262 (44%), Gaps = 19/262 (7%)

Query: 1   MLVAAGQFAVTSVWEK---NAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSA 57
           M++  GQ  V  +WE    N +    L+ +A+  D  L   PE  L        L ++  
Sbjct: 1   MIIGIGQIDV--LWEDYFANMKKIKILVEEASIKDVELILFPEMALT----GVTLDIEKL 54

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
            L   E +   R  + +N +   L            N ++    G ++  Y+K+HL+  +
Sbjct: 55  ILERDEIVSWCRELAIKNNINIGLGYGKKIDNKGLNNYIIISNLGEVLCDYSKIHLF-TY 113

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
             +     +  N +    ++ G  +    CYDLRFPE+    A + A+++ + A W    
Sbjct: 114 GGEPKAYYNGMNVLD--YQIGGFTMSSFICYDLRFPEI-FQLAARKAQVITIAANWPESK 170

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIM 233
           + E  W + L  RAL+T  Y++     G     K  G+S I+ P+G  +   S+   L++
Sbjct: 171 IDE--WISFLKVRALETQSYIIGINRLGEGDGIKYNGKSAIVSPWGDILNDLSDKEELVI 228

Query: 234 AEVTPERVRQVRAQLPVLNNRR 255
            E+  E+V + RA+  V ++RR
Sbjct: 229 QEIKLEQVFKSRAKFNVKDDRR 250


>UniRef50_A5TTZ3 Possible amidohydrolase n=4 Tax=Fusobacterium RepID=A5TTZ3_FUSNP
          Length = 274

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 59/246 (23%), Positives = 117/246 (47%), Gaps = 12/246 (4%)

Query: 15  EKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKR 74
           EKN +     + +AA+ +  +   PE          D      +     F+ +L+ ++K 
Sbjct: 24  EKNCKKIFERIEEAAKENVDIICFPELATIGYTITTDELQNLPEDFNNTFIEKLQEKAKL 83

Query: 75  ---NMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQESRRVDAGNE 130
              +++   L           +N  + +   G I+A   K++L+     +E  +  AG++
Sbjct: 84  FKIHILVGYLESKTTKKSKDFYNSCIFIDDEGKILANARKVYLWK----KEKTKFKAGDK 139

Query: 131 IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAAR 190
              + + +  K+G++ CYDL F E A  + L+GAEI+ +P+ W      E+ W   LAA 
Sbjct: 140 FI-VKDTKFGKIGILICYDLEFFEPARIECLKGAEIIFVPSLWSLNA--ENRWHIDLAAN 196

Query: 191 ALDTTCYMVAAGECGNKNIGQSRIIDPFGVT-IAAASEMPALIMAEVTPERVRQVRAQLP 249
           +L    +MV     G+   G+S+I++P G T I A+     L++A +   ++ ++R ++P
Sbjct: 197 SLFNLLFMVGCNAVGDSCCGKSKIVEPNGSTLIEASGTKEELLLATIDLAKLDEIRNKIP 256

Query: 250 VLNNRR 255
            L++ +
Sbjct: 257 YLSDFK 262


>UniRef50_B8FEV8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FEV8_DESAA
          Length = 266

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 58/176 (32%), Positives = 87/176 (49%), Gaps = 19/176 (10%)

Query: 88  TPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQE----SRRVDAGNEIAPLLEVEGMKV 142
           TP   +N    + + G++ A Y K+H +      E    +R V A    AP       K 
Sbjct: 88  TPDGVYNTHYYINEKGSVQAEYRKVHRFTPAGEGEFEPGARSVLAA---APW-----GKT 139

Query: 143 GLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAG 202
           GL+TCYDLRFPE + A  L GA +L++ A W    ++  HW  LL ARA++   +++A  
Sbjct: 140 GLLTCYDLRFPEQSRALVLAGAIVLIVSAQWP--AVRIRHWDVLLQARAVENQAFVIACN 197

Query: 203 ECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
            CG        G+S +I P+G  IA A     L+ A +    V+  R ++P L +R
Sbjct: 198 RCGKDPELVYGGRSAVISPWGEVIAGAGGGETLLTAALNLYEVKDFRTRIPCLEHR 253


>UniRef50_A5FWH4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Acidiphilium cryptum JF-5 RepID=A5FWH4_ACICJ
          Length = 266

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 66/226 (29%), Positives = 103/226 (45%), Gaps = 9/226 (3%)

Query: 34  SLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAW 93
            L  LPE  L   +  A  + + A   EGE +GR R  +    +            G A 
Sbjct: 37  DLLVLPELFLTGYNLGAARARELALDPEGEQIGRARALAAEVGIALCFGFPERVGDGVAN 96

Query: 94  NMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFP 153
           + ++  +AG     Y K+HL   F   +        +  P++   G+ +GL  CYD+ FP
Sbjct: 97  SAILIDEAGGARLIYRKVHL---FGDLDRGMFALPGDGFPVVAWRGLSLGLAICYDIEFP 153

Query: 154 ELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NI 209
           E A   AL GA+++++P A +  P       +L+ ARA +   Y+  A  CG +     I
Sbjct: 154 ETARMMALAGADLILVPTALM--PPYYVVADSLIPARAYENQVYIAYANHCGGEPGIDYI 211

Query: 210 GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G S I  P G  +A A   P  +MA + P  + +VR + P+L +RR
Sbjct: 212 GHSSICGPDGAVLAKAGAGPTRLMARIDPGHLAEVRRRDPLLADRR 257


>UniRef50_Q5B724 Putative uncharacterized protein n=1 Tax=Emericella nidulans
           RepID=Q5B724_EMENI
          Length = 199

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 68/235 (28%), Positives = 105/235 (44%), Gaps = 50/235 (21%)

Query: 33  ASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRA 92
           A+LF LPEA        A+    +  + E EF+  L+ E++ N +   + IH P+  GR 
Sbjct: 4   AALF-LPEAADYIGSSPAETISLARPVQESEFVLGLQSEARDNNLHINVGIHEPAANGRV 62

Query: 93  WNMLVALQ-AGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLR 151
            N L+ +   G I  RY KL                                       R
Sbjct: 63  KNTLIWIDDKGYITQRYQKL---------------------------------------R 83

Query: 152 FPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN--- 208
           FPE++LA   Q A+I+  P+A+   P    HW TLL ARA++T  Y++AA + G  N   
Sbjct: 84  FPEISLALRRQNAQIITYPSAFTV-PTGRAHWETLLRARAIETQSYVIAAAQAGPHNEKR 142

Query: 209 --IGQSRIIDPFGVTIAA---ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
              G S I++P+G  +A      E P +++A +  E + +VR ++P+L      P
Sbjct: 143 QSYGHSMIVNPWGEIMAKLGDEYEEPQIVVANIDLELLGKVRTEMPLLRRTDIYP 197


>UniRef50_C7NGT1 Predicted amidohydrolase n=1 Tax=Kytococcus sedentarius DSM 20547
           RepID=C7NGT1_KYTSD
          Length = 277

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 60/171 (35%), Positives = 88/171 (51%), Gaps = 14/171 (8%)

Query: 93  WN--MLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDL 150
           WN  ML A   G++VA Y K++ +  F   E+R ++AG ++     V      L TC+DL
Sbjct: 113 WNSSMLFA-PTGDLVATYRKVYRF-GFDSGEARTIEAGADLV-TAPVGPFTAHLATCFDL 169

Query: 151 RFPELALAQALQGAEILVLPAAWVRGPL-KEHHWSTLLAARALDTTCYMVAAGECG---- 205
           RFPE        GA++L++PAAW   P+ +  HW  LL ARA++    +VA    G    
Sbjct: 170 RFPEYFRDGLDAGADLLIVPAAW---PMARREHWRALLRARAIENQMPVVACNTAGTHAG 226

Query: 206 -NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            ++  G S IID  G  +A A +   ++ A +  E   Q R   PVL +RR
Sbjct: 227 DHEMGGASVIIDANGSVLAEAGDSQQVLRAVIDDEHTAQQRKNFPVLASRR 277


>UniRef50_Q9ZMC7 Putative n=14 Tax=Helicobacter RepID=Q9ZMC7_HELPJ
          Length = 294

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 71/262 (27%), Positives = 116/262 (44%), Gaps = 32/262 (12%)

Query: 16  KNAEICASLMAQAAENDASLFALPEAL---LARDDHDADLSVKSAQLLEGEFLGRLRRES 72
           +N ++  +L  +A    A+L  LPE        +D DAD  +    +  GE    L+ E+
Sbjct: 27  ENLQLALNLAKEAHNKGANLIVLPELFDSGYCVNDKDADFGLDFKAIEHGE--ETLKNET 84

Query: 73  KRNMM-------TTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQESRR 124
            R +        T I+   +     + ++    +   G IV ++ K++L+      E  R
Sbjct: 85  LRALSDFAKSSDTHIVACSIEKNNKKLYDSAYIIPPKGKIVGKHRKIYLWG----DEKSR 140

Query: 125 VDAGNEIAPLLEVEG---MKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEH 181
              G +        G    KVGL  CY+  F   A    LQGAE+L+ P+A+  G  + +
Sbjct: 141 FKRGKKYEVFTLDFGDFSAKVGLQICYETGFGVGANLLVLQGAEVLIYPSAF--GKARAY 198

Query: 182 HWSTLLAARALDTTCYMVAAGECGNKN----------IGQSRIIDPFGVTIAAASEMPAL 231
           +W  L  ARAL+  C++ A    G +            G SRII P G  IA A+++  +
Sbjct: 199 NWDLLSKARALENGCFVCACNHSGEETNAKLKQTLEFAGDSRIIAPNGKIIAQATKLNEV 258

Query: 232 IMAEVTPERVRQVRAQLPVLNN 253
           I+AE+    V   R ++P L +
Sbjct: 259 IIAEMDLNEVALQRQKIPYLQD 280


>UniRef50_B1MWQ8 Predicted amidohydrolase n=5 Tax=Lactobacillales RepID=B1MWQ8_LEUCK
          Length = 263

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 57/168 (33%), Positives = 89/168 (52%), Gaps = 13/168 (7%)

Query: 95  MLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPE 154
           M V  + G+ V+ Y KLHL+   A  E + + AG     +  + G+      CYD+RFPE
Sbjct: 97  MFVYDKNGHQVSTYNKLHLFGLMA--EEKFISAG-RTTNVFTLAGIPSAGAICYDIRFPE 153

Query: 155 -LALAQALQGAEILVLPAAWVRGPLKE-HHWSTLLAARALDTTCYMVAAGECG--NKNI- 209
            L    A+   EIL + A W   P++    W  LL ARA++   +++AA   G  + NI 
Sbjct: 154 WLRTMMAVGPQEILYIVAEW---PIQRIAQWQILLQARAIENQAFVIAANRVGHDDDNIF 210

Query: 210 -GQSRIIDPFGVTIAAASE-MPALIMAEVTPERVRQVRAQLPVLNNRR 255
            G+S IIDP G  +  AS+   AL++  +   + + +R ++PV N+RR
Sbjct: 211 GGRSLIIDPLGHIVGQASDTQEALLIRTIDISQEQAIRGEIPVFNDRR 258


>UniRef50_A5GU42 Nitrilase-related protein n=1 Tax=Synechococcus sp. RCC307
           RepID=A5GU42_SYNR3
          Length = 305

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 59/194 (30%), Positives = 97/194 (50%), Gaps = 28/194 (14%)

Query: 87  STPGRAWNMLVALQ-AGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGM 140
           S+ GR +N    +  AG ++A++ K+HL+D          ES  + AG++I  L  V   
Sbjct: 105 SSDGRIFNTATVISPAGCLLAKHRKMHLFDVDIPGGIHFHESDSLTAGDQITVLSGVGDP 164

Query: 141 ---------KVGLMTCYDLRFPELALAQALQ-GAEILVLPAAW--VRGPLKEHHWSTLLA 188
                     +GL  CYD+RFPELAL    Q   +++  PA +    GPL   HW  ++ 
Sbjct: 165 LASGAATPPNLGLQICYDIRFPELALLMQQQLSCDVIACPAGFSTTTGPL---HWHLVMR 221

Query: 189 ARALDTTCYMVAA------GECGN-KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERV 241
           ARA+DT  +++A        + G+  + G S ++DP+G  +A A     ++ AE+  +++
Sbjct: 222 ARAVDTQSFVLACCSARPPQDSGDYPSYGHSLVVDPWGHIVAEAGIGEEVVHAELDLDQI 281

Query: 242 RQVRAQLPVLNNRR 255
              RA +P    RR
Sbjct: 282 AAARAAIPTSRQRR 295


>UniRef50_Q4P4D1 Putative uncharacterized protein n=1 Tax=Ustilago maydis
           RepID=Q4P4D1_USTMA
          Length = 373

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 55/186 (29%), Positives = 82/186 (44%), Gaps = 33/186 (17%)

Query: 100 QAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPE 154
           + G +++ + KLHL+D         QES  +  G+ +  L +    + GL  CYDLRFPE
Sbjct: 183 EKGQLISIHRKLHLFDIDIPGKMTFQESETLAGGDRVT-LFDCSLGRFGLGICYDLRFPE 241

Query: 155 LALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAA----------- 201
            A+     GA  ++ P A+    GP+    W  LL ARA D   Y +             
Sbjct: 242 PAMIAGRLGAGCIIYPGAFNTTTGPV---SWELLLRARATDNQVYTLGCSPARPSQQALD 298

Query: 202 GECGNKN-----------IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPV 250
           GE  +K+            G S ++ P G   A  +E  A +   + PE V+Q R  +P+
Sbjct: 299 GELTDKDGWREGEKAYPAWGHSSVVGPLGDVKAKLAEAEATLFFTLDPEEVQQTRKNIPI 358

Query: 251 LNNRRF 256
              RRF
Sbjct: 359 STQRRF 364


>UniRef50_Q5KJU9 Hydrolase, putative n=1 Tax=Filobasidiella neoformans
           RepID=Q5KJU9_CRYNE
          Length = 301

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 65/212 (30%), Positives = 100/212 (47%), Gaps = 21/212 (9%)

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML----VALQAGNIVARYAKLHLYD- 115
           EGE +  LR E  R+    ++   +P    +  N+     V    G +VA + K+HL+D 
Sbjct: 84  EGETIKALR-EMARSSGCWLIGGSIPERDEKTDNIYNTCTVYDPEGTLVAVHQKVHLFDI 142

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES  +  G+ +       G K+GL  CYD+RFPE+A+  A QG   ++ PA
Sbjct: 143 DIPGKQTFKESDTLTGGSHLTTFTTPFG-KIGLGICYDIRFPEMAMIAARQGCIAMIYPA 201

Query: 172 AW--VRGPLKEHHWSTLLAARALDTTCYMVAAG-----ECGNKNIGQSRIIDPFGVTIAA 224
           A+    GP+   HW+ L  ARA+D   Y+         E   +  G S +++P G  +  
Sbjct: 202 AFNTTTGPM---HWTLLQRARAVDNEIYVAMCSPARHPEAAYQAYGHSSVVNPVGDVVVE 258

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           A   P  I A++ PE +   R  +PV   RRF
Sbjct: 259 ADHEPTTIYADIDPELLATTRRSIPVTVQRRF 290


>UniRef50_Q8TLM7 Carbon-nitrogen hydrolase n=2 Tax=Methanosarcina RepID=Q8TLM7_METAC
          Length = 309

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 52/168 (30%), Positives = 85/168 (50%), Gaps = 11/168 (6%)

Query: 93  WNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLR 151
           +N+    ++G +   Y K H + A    E+     G+ I P+ L+ + +K+GL  CY+LR
Sbjct: 141 YNLGFCFESGVLAGTYLKTHPFKA----ENGYFSKGSSIEPISLKKQNLKIGLEICYELR 196

Query: 152 FPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----K 207
           FPE+A   ++ G+++LV  AA+   P  E HW TL  ARA++     +A    G+     
Sbjct: 197 FPEVARKLSIAGSDLLVTIAAFPN-PRAE-HWKTLAKARAIENQIPHIACNRTGSVPDCT 254

Query: 208 NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
             G S IID +G   A A      I+ ++      ++R  +PV  +RR
Sbjct: 255 YFGNSMIIDAWGEIKAEAGSKECTIVCDLDLTGKEEIRKAIPVFEDRR 302


>UniRef50_B4MBJ2 GJ14457 n=5 Tax=Drosophila RepID=B4MBJ2_DROVI
          Length = 309

 Score = 81.3 bits (199), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 54/171 (31%), Positives = 81/171 (47%), Gaps = 20/171 (11%)

Query: 102 GNIVARYAKLHLY---------DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRF 152
           G ++ R+ KLHL+               E   + AGNE+  L+++   KVG+  C+D RF
Sbjct: 133 GQLIGRHRKLHLFCVNIEPEQLGGCQFDEGVALTAGNELT-LVQIGAHKVGIGICHDKRF 191

Query: 153 PELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK--- 207
            ELA     QG  +LV P+A+   +GP+   HW  L  ARA D   +++      N    
Sbjct: 192 EELARLYRNQGCSMLVYPSAFCICQGPM---HWELLQRARATDNQLFVITCAPARNNMSG 248

Query: 208 --NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
               G S I+DP+      A E   LI+  +  + V +VR Q+P+   RR 
Sbjct: 249 YVAYGHSMIVDPWARVQREAGEGRELIVETIDFDMVDEVRRQIPIYKQRRL 299


>UniRef50_Q2TYD8 Carbon-nitrogen hydrolase n=1 Tax=Aspergillus oryzae
           RepID=Q2TYD8_ASPOR
          Length = 244

 Score = 80.9 bits (198), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 54/171 (31%), Positives = 85/171 (49%), Gaps = 28/171 (16%)

Query: 93  WNMLVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGM-KVGLMT 146
           W++L     G ++A + K+HL+D       +  ES  + AG +    +++EG  ++GL  
Sbjct: 81  WHILSP--KGELIAFHRKMHLFDMDVPGGMSFHESDTLSAGKKTT-TVDLEGYGQIGLGV 137

Query: 147 CYDLRFPELALAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAAGEC 204
           CYD+RF EL+   A QGA  LV P+A+    GPL   HW  L  ARA+D           
Sbjct: 138 CYDMRFAELSTIAARQGAFALVYPSAFNTTTGPL---HWELLGRARAVD----------- 183

Query: 205 GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
              N G   + DP G  +A  ++   +  A + PE +++ R  +P+   RR
Sbjct: 184 ---NQGYGMVTDPMGQVVAGTNQSEDIAYALLHPETIKRSRMAIPITFQRR 231


>UniRef50_C5BSY0 Hydrolase, carbon-nitrogen family n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BSY0_TERTT
          Length = 302

 Score = 80.5 bits (197), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 56/176 (31%), Positives = 87/176 (49%), Gaps = 26/176 (14%)

Query: 102 GNIVARYAKLHLYDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPEL 155
           G I + Y K+HL+DA       A +ES     G+ +  + E    ++G+  CYDLRFPE 
Sbjct: 129 GRIASAYRKMHLFDADVKDNTGAYRESDSFARGD-MPVVCETPWGRMGVGICYDLRFPEY 187

Query: 156 ALAQALQGAEILVLPAA--WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KN 208
             A   QGA+ +VLP+A  W  G +   HW  LL ARA++    M+   + G      K 
Sbjct: 188 FRALRQQGADFVVLPSAFTWATGKV---HWELLLRARAVENQIVMIGVNQGGEHTPQRKT 244

Query: 209 IGQSRIIDPFGVTIAAASEMP---------ALIMAEVTPERVRQVRAQLPVLNNRR 255
            G S +++ +G  IA A +            L++ +V  + +  +R  +PV N+RR
Sbjct: 245 WGDSMVVNGWGEIIARAGDDKLLEDSQLGEHLVVTQVDLDELELLRKDMPVWNHRR 300


>UniRef50_P55176 UPF0012 hydrolase in pqqF 5'region n=22 Tax=Bacteria
           RepID=YPQQ_PSEFL
          Length = 285

 Score = 80.5 bits (197), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 57/174 (32%), Positives = 88/174 (50%), Gaps = 10/174 (5%)

Query: 87  STPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLM 145
           S  G+ +N +  + A G  +  Y K HL   F   +     AG +  PL+E++G K+G +
Sbjct: 107 SVDGQIYNAVQLIDAQGQRLCNYRKTHL---FGDLDHSMFSAGEDDFPLVELDGWKLGFL 163

Query: 146 TCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG 205
            CYD+ FPE A   AL GAE++++P A +     +      + ARA +  CY+  A  CG
Sbjct: 164 ICYDIEFPENARRLALAGAELILVPTANMIP--YDFVADVTIRARAFENQCYVAYANYCG 221

Query: 206 N----KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           +    +  GQS I  P G  IA A    ALI+  +  + + + RA    L++RR
Sbjct: 222 HEEQIRYCGQSSIAAPDGSRIALAGLDEALIIGTLDRQLMGESRALNRYLSDRR 275


>UniRef50_C4MAX0 Hydrolase yafV, putative n=2 Tax=Entamoeba RepID=C4MAX0_ENTHI
          Length = 206

 Score = 80.5 bits (197), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 53/184 (28%), Positives = 82/184 (44%), Gaps = 25/184 (13%)

Query: 90  GRAWNMLVALQAGNIVARYAKLHLY----DAFAIQESRRVDAGNEIAPLLEVEGMKVGLM 145
           G+ +N +  +     V  Y K HLY    +     + ++    N +       G K+ L 
Sbjct: 22  GKYYNRVYFVTPQQEVYEYNKRHLYTMGNEGICFTKGQKKTVVNYL-------GWKINLA 74

Query: 146 TCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG 205
            CYDLRFP           +IL++ A W R   K HHW TL  ARA++  CY++A+  CG
Sbjct: 75  ICYDLRFPNWLRNSKEDPYDILLIVACW-RAE-KRHHWITLTTARAIENQCYVIASNNCG 132

Query: 206 -----NKNI------GQSRIIDPFGVTIAAASE-MPALIMAEVTPERVRQVRAQLPVLNN 253
                  N       G  R +D FG +I  A   +  +I + +  +++   RA  PVLN+
Sbjct: 133 ILPDTTPNCPDVVYTGDCRFVDYFGYSIKEAKPGVEQIIYSTLDYQKLLDWRAHFPVLND 192

Query: 254 RRFA 257
             + 
Sbjct: 193 ADYC 196


>UniRef50_A8LPZ9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=28 Tax=Alphaproteobacteria RepID=A8LPZ9_DINSH
          Length = 277

 Score = 80.5 bits (197), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 57/187 (30%), Positives = 88/187 (47%), Gaps = 17/187 (9%)

Query: 81  LTIHVPSTPGRAWNMLVALQAGN-IVARYAKLHLYD-AFAIQESRRVDAG---NEIAPLL 135
           L +      GR  N  + + AG  I ARY K+H++D A +  E+ R   G    + A L 
Sbjct: 84  LAVTTEDAEGRFANRSILIDAGGGIAARYDKIHMFDVAVSEAETYRESDGYRPGDRAVLA 143

Query: 136 EVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK-EHHWSTLLAARALDT 194
           +    K+G+  CYDLRFP L    A  GAEIL +P+A+   P+    HW  LL ARA++ 
Sbjct: 144 DTPFGKIGMTVCYDLRFPHLFRDLARAGAEILTVPSAF--SPVTGAAHWEPLLRARAIEC 201

Query: 195 TCYMVAAGECGN---------KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVR 245
             +++A  + G             G S  +DP+G  +A     P +   ++    +   R
Sbjct: 202 GAWVLAPAQTGTHPATRGKARSTHGHSLAVDPWGRVLADGGTAPGVCFVDLDRTEIAAAR 261

Query: 246 AQLPVLN 252
            ++P L 
Sbjct: 262 RKIPSLT 268


>UniRef50_B0X5I4 Hydrolase n=5 Tax=Culicidae RepID=B0X5I4_CULQU
          Length = 279

 Score = 80.5 bits (197), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 49/166 (29%), Positives = 82/166 (49%), Gaps = 16/166 (9%)

Query: 102 GNIVARYAKLHLYDA-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELA 156
           G  + +Y K+HL+D          ES  +  G E      VEG+ VG+  CYD RFPE A
Sbjct: 108 GEFIGKYRKMHLFDMDIPGICTFSESSVLTPGKEFL-TFSVEGLNVGIGICYDQRFPEFA 166

Query: 157 LAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCY--MVAAGECGNKN---I 209
                 G + L+ P+A+    GP+   H+  +  ARALD + +  + A     +K+    
Sbjct: 167 AIHRQLGTDFLIFPSAFDTYTGPM---HFELIARARALDNSMFVALCAPARDTSKDYVAY 223

Query: 210 GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G S + DP+G  +  A E P +++ ++    +  ++ ++PVL  +R
Sbjct: 224 GYSTLCDPWGRVVCRAGEHPEMLVVDLDLTLLEDIKKKIPVLKQKR 269


>UniRef50_Q30T00 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Sulfurimonas denitrificans DSM 1251
           RepID=Q30T00_SULDN
          Length = 260

 Score = 80.1 bits (196), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 66/260 (25%), Positives = 121/260 (46%), Gaps = 27/260 (10%)

Query: 9   AVTSVWE---KNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFL 65
           ++  +WE   KN  +C   + +A E  A L   PE  L    ++    V++ +  + + +
Sbjct: 7   SLNQIWEDKDKNLILCEKNIQKAVEGKADLIIFPEMTLTGFSNNIPFIVENIE--DSKTI 64

Query: 66  GRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESR 123
                 +K+    T L   V    G +A N  V + + G+++ +Y+K+H +  FA  E +
Sbjct: 65  KEFSSLAKK--YNTALVFGVAIKDGDKALNKAVFIDKNGSVLGKYSKIHPF-TFA-GEDK 120

Query: 124 RVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE-HH 182
             +AGN +  ++  E  K+GL  CYDLRFPEL  + A +  ++++  A W   P K   H
Sbjct: 121 YFNAGNSL-EIVNFENFKIGLTICYDLRFPELYSSLA-KSCDLVINIANW---PFKRVAH 175

Query: 183 WSTLLAARALDTTCYMVAAGECG--NKNIGQSRIIDPFG-----VTIAAASEMPALIMAE 235
           W+TLL ARA++   ++      G    N+      + F      V      EM    + E
Sbjct: 176 WNTLLKARAIENQIFIAGINRVGVDGNNLEYCESSNMFNANGEQVYFEQIDEMK---LYE 232

Query: 236 VTPERVRQVRAQLPVLNNRR 255
           +  +  ++ +++    N+R+
Sbjct: 233 IEKDWTKEFKSKFNTTNDRK 252


>UniRef50_B6B254 Hydrolase in PqqF 5'region n=1 Tax=Rhodobacterales bacterium
           HTCC2083 RepID=B6B254_9RHOB
          Length = 261

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 69/247 (27%), Positives = 116/247 (46%), Gaps = 15/247 (6%)

Query: 16  KNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRN 75
           +NA +     A A   +A L   PE  L   +  AD   K A+  +G  +  LR  +K +
Sbjct: 17  ENAALFDQACADAKSGNADLIIFPEMALTGYNIGADRIRKLAEPCDGPMIQTLRDMAKHH 76

Query: 76  MMTTILTIHVPSTPG-RAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIAP 133
            +  +     P   G + +N  V + A G++++   K HL   F   +       + + P
Sbjct: 77  RIGVVCGF--PELDGEQVFNAAVIIDAAGSVLSICRKAHL---FGDVDRAAFSPADTLCP 131

Query: 134 LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWST-LLAARAL 192
           L++     VG   CYD+ FPEL  A AL GA+I+++P A +   L     +T ++ ARA 
Sbjct: 132 LVQFGDWSVGFAICYDVEFPELVRAYALAGADIVLVPTANM---LPYVGIATRVVPARAE 188

Query: 193 DTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQL 248
           +   Y+  A   G +      G S ++ P G  +A A     L++A+++ E +  +R+ L
Sbjct: 189 ENEIYVAYANRVGREGAFEYCGLSCVVGPDGNDVARAGRNEELMIADISKETIAHIRSSL 248

Query: 249 PVLNNRR 255
             LN+RR
Sbjct: 249 SHLNDRR 255


>UniRef50_A4SNH5 Amidohydrolase family protein n=2 Tax=Proteobacteria
           RepID=A4SNH5_AERS4
          Length = 284

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 59/181 (32%), Positives = 94/181 (51%), Gaps = 18/181 (9%)

Query: 89  PGRAWN--MLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEV--EGMKVGL 144
           PG+  N  +L+  Q G + +RY KLHL+     QE  + D    ++P  EV    +  G+
Sbjct: 101 PGKMHNSSLLIDPQ-GALASRYDKLHLFGFCTGQE--QYDEAATMSPGREVVSHPLPWGM 157

Query: 145 M---TCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAA 201
           +    CYDLRFPEL         + + LPAA+        HW  LL ARA++   +++A+
Sbjct: 158 LRFGICYDLRFPELFRLDP--APDFIALPAAFTH-TTGLAHWELLLRARAVENLAFVLAS 214

Query: 202 GECGN-----KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            + G+     +  G S IIDP+G  +A   E   + +A +     R+VR+QLP L++R+ 
Sbjct: 215 AQGGHHPGGRRTFGHSMIIDPWGQVLARVEEGHGMAIATLDLAAQRKVRSQLPALSHRKI 274

Query: 257 A 257
           +
Sbjct: 275 S 275


>UniRef50_UPI0001BC35FB amidohydrolase n=1 Tax=Butyrivibrio crossotus DSM 2876
           RepID=UPI0001BC35FB
          Length = 258

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 51/168 (30%), Positives = 88/168 (52%), Gaps = 11/168 (6%)

Query: 93  WNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLR 151
           +N  V +   G I+  Y K+H +  +A  E R  + G+ ++   +++ + V  + CYDLR
Sbjct: 90  YNTYVIIDNLGKIICSYDKIHPF-TYA-GEDRVYEKGSSLS-FCQIDDITVCPLICYDLR 146

Query: 152 FPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK---- 207
           FPEL + +A + A+++ + AA   GP ++ HW  LL ARA++   Y+      G      
Sbjct: 147 FPELFI-KASKKADLITV-AANFGGP-RDGHWQVLLKARAIENQTYIAGINRAGEDVSTY 203

Query: 208 NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            +G S  + P G  I+ A E   +I+A++  E   + R + PV N+ R
Sbjct: 204 YMGHSMAVSPKGDVISMAGEKEDIIIADIDKEEEYEYRKKFPVRNDFR 251


>UniRef50_A6LLW0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermosipho melanesiensis BI429
           RepID=A6LLW0_THEM4
          Length = 264

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 61/256 (23%), Positives = 114/256 (44%), Gaps = 27/256 (10%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           ML+AA QF      +E N       + +AA  +A L   PE  ++   +D  + + S   
Sbjct: 1   MLIAAAQFEPKPGDFEGNYAKHLKFIDEAASLEARLILFPELSISGYTYDRKILLSSIDF 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVAR-------YAKLH 112
                     R+ +  ++      ++    G    +L+ ++    V R       Y K H
Sbjct: 61  F---------RQKRNELIYLSRKYNMAIVGGIPRKILLEIRNSVFVVRKKKQILFYDKTH 111

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
           L+     ++ + V +  E   + +  G++ G++ CY++ FPE++    L GA++L+ P A
Sbjct: 112 LF-----RKEKEVFSPGERFLVFKFNGVRFGILVCYEIGFPEISRILTLNGAQVLLAPFA 166

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN---KNIGQSRIIDPFGVTIAAASEMP 229
           +  G  ++H +     ARAL+   Y+V +   G      +G SRI+ P G  + +A +  
Sbjct: 167 F--GRERKHIYDIATRARALENGAYLVTSSTSGKGLMNFLGSSRIVGPDGSVLVSARKKE 224

Query: 230 ALIMAEVTPERVRQVR 245
            LI  +V+ E +   R
Sbjct: 225 QLIYYDVSVENLEFFR 240


>UniRef50_D1BL17 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Veillonellaceae RepID=D1BL17_VEIPT
          Length = 263

 Score = 78.2 bits (191), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 41/160 (25%), Positives = 74/160 (46%), Gaps = 9/160 (5%)

Query: 100 QAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQ 159
           + G +V  Y+K+H    F+  +  +  A        E++G+    + CYD+RFPEL    
Sbjct: 103 RKGTLVGEYSKMH---GFSPAKEDQYFASGTHTTHFELDGIPCSTVICYDIRFPELVRMA 159

Query: 160 ALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRII 215
           AL   E+L +PA W    L+  HW  L   RA++   ++ A   CG     ++ G S + 
Sbjct: 160 ALSNTELLFVPAQWPTMRLR--HWQVLNEVRAIENQLFLCAVNGCGTVGRVQSTGHSAVY 217

Query: 216 DPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           DP+G  +        +   ++    V  +R ++ +  +R+
Sbjct: 218 DPWGTNLLEMDTREGISSIDIDLTVVEDIRNKINIFRDRK 257


>UniRef50_C5L8W7 Putative uncharacterized protein n=2 Tax=Perkinsus marinus ATCC
           50983 RepID=C5L8W7_9ALVE
          Length = 300

 Score = 78.2 bits (191), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 54/181 (29%), Positives = 79/181 (43%), Gaps = 23/181 (12%)

Query: 96  LVALQAGNIVARYAKLHLYD----------AFAIQESRRVDAGNEIAPLLEVEGMKVGLM 145
           LV   +G +V  Y K HL+D               ES  +  GN    + +      GL 
Sbjct: 110 LVVNSSGELVKTYRKAHLFDIDVPADGDKPGIRFFESETLSPGNSGPCVFDTPWGPFGLG 169

Query: 146 TCYDLRFPELA--LAQALQGAEILVLPAAW--VRGPLKEHHWSTLLAARALDTTCYMVAA 201
            CYD+RFPE A  L       ++L+ P A+    GP    HW  L  ARALDT CY+V A
Sbjct: 170 ICYDVRFPEYAALLRNIAPDLKMLIYPGAFNMTTGPA---HWRLLGRARALDTQCYVVMA 226

Query: 202 GECGNKN------IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
               ++N       G S +++P+G  +    E       +V    V +VR  +P  + +R
Sbjct: 227 SPSRSENPEDYQAWGHSMVVNPWGEVVDETDEKHGWFTVDVDLTMVDRVRRNIPTASQKR 286

Query: 256 F 256
           +
Sbjct: 287 Y 287


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P58054 UPF0012 hydrolase ybeM n=121 Tax=Proteobacteria ...   361   2e-98
UniRef50_C0Z4R2 Putative uncharacterized protein n=1 Tax=Breviba...   307   3e-82
UniRef50_UPI0001924654 PREDICTED: similar to Nit protein 1 n=1 T...   293   3e-78
UniRef50_Q28IE5 Omega-amidase NIT2 n=42 Tax=cellular organisms R...   292   6e-78
UniRef50_A7A823 Putative uncharacterized protein n=2 Tax=Bifidob...   292   7e-78
UniRef50_UPI000186DBB5 conserved hypothetical protein n=1 Tax=Pe...   291   2e-77
UniRef50_UPI000197C0D6 hypothetical protein PretD1_21713 n=1 Tax...   291   2e-77
UniRef50_B9ZGS1 Nitrilase/cyanide hydratase and apolipoprotein N...   290   4e-77
UniRef50_Q9NQR4 Omega-amidase NIT2 n=88 Tax=Eukaryota RepID=NIT2...   288   1e-76
UniRef50_Q7TQ94 Nitrilase homolog 1 n=6 Tax=Coelomata RepID=NIT1...   288   1e-76
UniRef50_Q86X76 Nitrilase homolog 1 n=34 Tax=Eumetazoa RepID=NIT...   284   2e-75
UniRef50_B9L3Z7 Hydrolase, carbon-nitrogen family protein n=8 Ta...   284   2e-75
UniRef50_UPI000051A529 PREDICTED: similar to Nitrilase and fragi...   283   3e-75
UniRef50_Q9HIW8 Nitrilase related protein n=2 Tax=Thermoplasma R...   283   5e-75
UniRef50_A9A651 Nitrilase/cyanide hydratase and apolipoprotein N...   282   7e-75
UniRef50_A1HPP3 Nitrilase/cyanide hydratase and apolipoprotein N...   281   2e-74
UniRef50_UPI00019771AF Nitrilase/cyanide hydratase and apolipopr...   280   3e-74
UniRef50_C8VW38 Nitrilase/cyanide hydratase and apolipoprotein N...   279   6e-74
UniRef50_A9WV78 Hydrolase, carbon-nitrogen family n=3 Tax=Microc...   277   3e-73
UniRef50_C1TRG7 Predicted amidohydrolase n=1 Tax=Dethiosulfovibr...   276   5e-73
UniRef50_Q2QQ94 Os12g0502500 protein n=5 Tax=Spermatophyta RepID...   274   2e-72
UniRef50_C6CYG4 Nitrilase/cyanide hydratase and apolipoprotein N...   273   4e-72
UniRef50_O76463 Nitrilase homolog n=6 Tax=Bilateria RepID=NFT1_C...   272   9e-72
UniRef50_A5N8H1 Predicted hydrolase n=3 Tax=Clostridium RepID=A5...   271   1e-71
UniRef50_B0SIF2 Amidohydrolase n=3 Tax=Bacteria RepID=B0SIF2_LEPBA    271   2e-71
UniRef50_Q0S3S2 Possible amidohydrolase, carbon-nitrogen hydrola...   270   4e-71
UniRef50_D2R0U8 Nitrilase/cyanide hydratase and apolipoprotein N...   270   5e-71
UniRef50_Q8RUF8 AT5g12040/F14F18_210 n=16 Tax=Eukaryota RepID=Q8...   270   5e-71
UniRef50_Q702A9 Putative predicted amidohydrolase n=6 Tax=Archae...   268   1e-70
UniRef50_O76464 Nitrilase homolog n=6 Tax=Sophophora RepID=NFT1_...   267   2e-70
UniRef50_D1Y612 Hydrolase n=2 Tax=Bacteria RepID=D1Y612_9BACT         267   2e-70
UniRef50_B2J6W4 Nitrilase/cyanide hydratase and apolipoprotein N...   267   3e-70
UniRef50_B9HD27 Predicted protein n=8 Tax=Magnoliophyta RepID=B9...   266   4e-70
UniRef50_A4ALG5 Putative hydrolase n=1 Tax=marine actinobacteriu...   266   7e-70
UniRef50_P55175 UPF0012 hydrolase sll0601 n=46 Tax=Cyanobacteria...   265   8e-70
UniRef50_Q2NHR0 Predicted amidohydrolase n=1 Tax=Methanosphaera ...   265   9e-70
UniRef50_Q557J5 Nitrilase homolog 1 n=1 Tax=Dictyostelium discoi...   265   1e-69
UniRef50_D2RIK2 Nitrilase/cyanide hydratase and apolipoprotein N...   265   1e-69
UniRef50_A2BNC1 Predicted amidohydrolase n=1 Tax=Hyperthermus bu...   264   2e-69
UniRef50_Q7MHE3 Predicted amidohydrolase n=69 Tax=Proteobacteria...   263   3e-69
UniRef50_B0MEV6 Putative uncharacterized protein n=2 Tax=Clostri...   263   3e-69
UniRef50_Q1PXD4 Similar to N-carbamoyl-D-amino acid hydrolase n=...   263   3e-69
UniRef50_B6HUF1 Pc22g05380 protein n=28 Tax=Leotiomyceta RepID=B...   263   4e-69
UniRef50_C1SI84 Predicted amidohydrolase n=1 Tax=Denitrovibrio a...   262   9e-69
UniRef50_D2A1E5 Putative uncharacterized protein GLEAN_07103 n=3...   261   2e-68
UniRef50_A1SD43 Nitrilase/cyanide hydratase and apolipoprotein N...   261   2e-68
UniRef50_C4DVK2 Predicted amidohydrolase n=1 Tax=Stackebrandtia ...   261   2e-68
UniRef50_A2Q9D7 Catalytic activity: nitrilases catalyze a nitril...   260   3e-68
UniRef50_Q23ND3 Hydrolase, carbon-nitrogen family protein n=1 Ta...   260   4e-68
UniRef50_UPI0001B416B7 carbon-nitrogen hydrolase n=1 Tax=Ferropl...   259   7e-68
UniRef50_B2SXB2 Nitrilase/cyanide hydratase and apolipoprotein N...   259   7e-68
UniRef50_Q54JM9 Nitrilase homolog 2 n=1 Tax=Dictyostelium discoi...   259   7e-68
UniRef50_Q6L0F7 Carbon-nitrogen hydrolase family n=1 Tax=Picroph...   259   7e-68
UniRef50_B3E274 Nitrilase/cyanide hydratase and apolipoprotein N...   258   1e-67
UniRef50_B1I274 Nitrilase/cyanide hydratase and apolipoprotein N...   258   1e-67
UniRef50_A0L7H1 Nitrilase/cyanide hydratase and apolipoprotein N...   258   1e-67
UniRef50_Q0AX54 N-carbamoyl-D-amino acid amidohydrolase n=3 Tax=...   258   2e-67
UniRef50_A5GT50 Possible nitrilase n=5 Tax=Bacteria RepID=A5GT50...   258   2e-67
UniRef50_Q0HEI5 Nitrilase/cyanide hydratase and apolipoprotein N...   257   2e-67
UniRef50_Q94JV5 AT4g08790/T32A17_100 n=10 Tax=Viridiplantae RepI...   257   2e-67
UniRef50_B5JWE9 Nitrilase/cyanide hydratase and apolipoprotein N...   257   3e-67
UniRef50_Q7QKM8 AGAP012662-PA (Fragment) n=14 Tax=Neoptera RepID...   256   5e-67
UniRef50_Q2BKP4 Putative carbon-nitrogen hydrolase n=1 Tax=Neptu...   256   5e-67
UniRef50_D1Y5M0 Hydrolase C26A3.11 n=1 Tax=Pyramidobacter piscol...   255   8e-67
UniRef50_A3ZLM3 Putative nitrilase n=1 Tax=Blastopirellula marin...   255   8e-67
UniRef50_D1BX77 Nitrilase/cyanide hydratase and apolipoprotein N...   255   1e-66
UniRef50_Q9LE50 Nitrilase 1 like protein n=2 Tax=Viridiplantae R...   255   1e-66
UniRef50_A2FF61 Hydrolase NIT3, putative n=4 Tax=cellular organi...   254   2e-66
UniRef50_B0TEY4 Hydrolase, carbon-nitrogen family n=1 Tax=Heliob...   254   3e-66
UniRef50_A8I529 Carbon-nitrogen hydrolase family protein n=8 Tax...   253   4e-66
UniRef50_A5V962 Nitrilase/cyanide hydratase and apolipoprotein N...   253   5e-66
UniRef50_D1Y828 Hydrolase n=1 Tax=Pyramidobacter piscolens W5455...   252   8e-66
UniRef50_A6F4Z1 Predicted amidohydrolase n=2 Tax=Marinobacter Re...   252   1e-65
UniRef50_Q6C005 YALI0F29139p n=1 Tax=Yarrowia lipolytica RepID=Q...   252   1e-65
UniRef50_Q0F1V1 Hydrolase, carbon-nitrogen family protein n=1 Ta...   252   1e-65
UniRef50_B2SLI2 Beta-alanine synthetase n=122 Tax=Bacteria RepID...   252   1e-65
UniRef50_D1A7Y1 Nitrilase/cyanide hydratase and apolipoprotein N...   251   2e-65
UniRef50_C7R9G8 Nitrilase/cyanide hydratase and apolipoprotein N...   251   2e-65
UniRef50_D2UDH5 Putative carbon-nitrogen hydrolase family protei...   251   2e-65
UniRef50_C8WPR2 Nitrilase/cyanide hydratase and apolipoprotein N...   251   2e-65
UniRef50_Q12ZA5 Carbon-nitrogen hydrolase family protein n=1 Tax...   250   3e-65
UniRef50_Q972L1 281aa long hypothetical beta-ureidopropionase n=...   250   3e-65
UniRef50_C7ICC9 Nitrilase/cyanide hydratase and apolipoprotein N...   250   5e-65
UniRef50_A6DKQ0 Carbon-nitrogen hydrolase family protein n=1 Tax...   249   7e-65
UniRef50_A6VWN8 Nitrilase/cyanide hydratase and apolipoprotein N...   249   8e-65
UniRef50_A1RZK0 Nitrilase/cyanide hydratase and apolipoprotein N...   249   8e-65
UniRef50_O94660 Probable hydrolase nit2 n=2 Tax=Schizosaccharomy...   248   9e-65
UniRef50_A4SSL0 Beta-ureidopropionase n=2 Tax=Gammaproteobacteri...   248   1e-64
UniRef50_A1HQ26 Nitrilase/cyanide hydratase and apolipoprotein N...   248   2e-64
UniRef50_A8MG18 Nitrilase/cyanide hydratase and apolipoprotein N...   248   2e-64
UniRef50_C4XZI3 Putative uncharacterized protein n=1 Tax=Clavisp...   247   3e-64
UniRef50_B6K212 UPF0012 hydrolase n=1 Tax=Schizosaccharomyces ja...   247   3e-64
UniRef50_Q3SLE9 Carbon-nitrogen hydrolase n=101 Tax=Proteobacter...   246   4e-64
UniRef50_A7IJX5 Nitrilase/cyanide hydratase and apolipoprotein N...   246   6e-64
UniRef50_A0PVY5 Amidohydrolase n=12 Tax=Actinomycetales RepID=A0...   246   6e-64
UniRef50_A0JSW0 Nitrilase/cyanide hydratase and apolipoprotein N...   246   7e-64
UniRef50_C6N396 Nitrilase n=2 Tax=Legionella RepID=C6N396_9GAMM       245   1e-63
UniRef50_D0LZ94 Nitrilase/cyanide hydratase and apolipoprotein N...   245   1e-63
UniRef50_O31664 UPF0012 hydrolase mtnU n=96 Tax=Bacilli RepID=MT...   245   1e-63
UniRef50_A7GE66 Hydrolase, carbon-nitrogen family n=24 Tax=cellu...   245   1e-63
UniRef50_Q2JDM2 Nitrilase/cyanide hydratase and apolipoprotein N...   245   2e-63
UniRef50_A5G317 Nitrilase/cyanide hydratase and apolipoprotein N...   244   2e-63
UniRef50_D2RS34 Nitrilase/cyanide hydratase and apolipoprotein N...   243   4e-63
UniRef50_P47016 Probable hydrolase NIT2 n=9 Tax=Saccharomycetace...   243   4e-63
UniRef50_C0GEE7 Nitrilase/cyanide hydratase and apolipoprotein N...   243   4e-63
UniRef50_D0L1I4 Nitrilase/cyanide hydratase and apolipoprotein N...   243   5e-63
UniRef50_Q1LEX6 Nitrilase/cyanide hydratase and apolipoprotein N...   243   5e-63
UniRef50_Q6SHH5 Carbon-nitrogen hydrolase family protein n=2 Tax...   243   6e-63
UniRef50_A1WYY7 Nitrilase/cyanide hydratase and apolipoprotein N...   242   7e-63
UniRef50_Q1YU23 Hydrolase, carbon-nitrogen family protein n=1 Ta...   242   8e-63
UniRef50_C2BXL2 Cyanide hydratase n=1 Tax=Listeria grayi DSM 206...   242   9e-63
UniRef50_A4XQL4 Nitrilase/cyanide hydratase and apolipoprotein N...   242   9e-63
UniRef50_A4S5E0 Predicted protein n=2 Tax=Ostreococcus RepID=A4S...   242   1e-62
UniRef50_Q9KE11 BH1047 protein n=2 Tax=Bacillaceae RepID=Q9KE11_...   241   1e-62
UniRef50_A5VIE2 Nitrilase/cyanide hydratase and apolipoprotein N...   241   1e-62
UniRef50_Q11M91 Nitrilase/cyanide hydratase and apolipoprotein N...   241   2e-62
UniRef50_D1VY57 Hydrolase, carbon-nitrogen family n=1 Tax=Prevot...   240   3e-62
UniRef50_A7I5W9 Porphyromonas-type peptidyl-arginine deiminase n...   240   3e-62
UniRef50_C7NXL9 Nitrilase/cyanide hydratase and apolipoprotein N...   240   3e-62
UniRef50_D0RND5 Hydrolase n=1 Tax=alpha proteobacterium HIMB114 ...   240   4e-62
UniRef50_Q5DC61 SJCHGC06938 protein n=1 Tax=Schistosoma japonicu...   240   4e-62
UniRef50_UPI0000E7FA0A PREDICTED: hypothetical protein isoform 1...   240   4e-62
UniRef50_A0LQU6 Nitrilase/cyanide hydratase and apolipoprotein N...   240   5e-62
UniRef50_Q15ZG7 Nitrilase/cyanide hydratase and apolipoprotein N...   240   5e-62
UniRef50_Q1AWK1 Nitrilase/cyanide hydratase and apolipoprotein N...   239   6e-62
UniRef50_C8S929 Nitrilase/cyanide hydratase and apolipoprotein N...   239   6e-62
UniRef50_Q9Y9L1 Putative hydrolase n=1 Tax=Aeropyrum pernix RepI...   239   9e-62
UniRef50_B4RQA3 Nitrilase n=28 Tax=Neisseriaceae RepID=B4RQA3_NEIG2   238   1e-61
UniRef50_A3WPW5 Predicted amidohydrolase, nitrilase family proti...   238   1e-61
UniRef50_Q0S9Y1 Possible nitrilase n=3 Tax=Actinomycetales RepID...   238   1e-61
UniRef50_C1AA71 N-carbamoylputrescine amidohydrolase n=12 Tax=Ba...   238   1e-61
UniRef50_A1SU00 Nitrilase/cyanide hydratase and apolipoprotein N...   238   1e-61
UniRef50_C7N2Y0 Predicted amidohydrolase n=1 Tax=Slackia heliotr...   238   1e-61
UniRef50_C6JLR5 Nitrilase/cyanide hydratase and apolipoprotein N...   238   2e-61
UniRef50_Q724C2 Hydrolase, carbon-nitrogen family n=20 Tax=Bacil...   237   2e-61
UniRef50_Q5WM18 Methylthioribose recycling protein n=3 Tax=Bacil...   237   2e-61
UniRef50_C6B8T0 Nitrilase/cyanide hydratase and apolipoprotein N...   237   2e-61
UniRef50_B8C1M9 Nitrilase n=1 Tax=Thalassiosira pseudonana RepID...   236   4e-61
UniRef50_Q0VS65 Carbon-nitrogen hydrolase family protein n=2 Tax...   236   6e-61
UniRef50_C0D6C3 Putative uncharacterized protein n=1 Tax=Clostri...   236   7e-61
UniRef50_C0VX65 Nitrilase/cyanide hydratase and apolipoprotein N...   235   1e-60
UniRef50_D2VM50 Predicted protein n=1 Tax=Naegleria gruberi RepI...   235   1e-60
UniRef50_Q46AW4 Putative amidohydrolase n=1 Tax=Methanosarcina b...   235   1e-60
UniRef50_B9JB81 Amidohydrolase protein n=4 Tax=cellular organism...   235   1e-60
UniRef50_B6YW48 Carbon-nitrogen hydrolase n=4 Tax=cellular organ...   235   2e-60
UniRef50_A8RJL1 Putative uncharacterized protein n=1 Tax=Clostri...   234   2e-60
UniRef50_C4QCM8 Nitrilase-related n=1 Tax=Schistosoma mansoni Re...   234   2e-60
UniRef50_C9KQR5 Hydrolase, carbon-nitrogen family n=1 Tax=Mitsuo...   234   2e-60
UniRef50_C1GYG0 Hydrolase n=1 Tax=Paracoccidioides brasiliensis ...   234   2e-60
UniRef50_Q5A428 Nitrilase superfamily protein n=4 Tax=Candida Re...   234   2e-60
UniRef50_C7TF35 Hydrolase, carbon-nitrogen family n=17 Tax=Lacto...   234   3e-60
UniRef50_Q3IFH8 Putative hydrolase, carbon-nitrogen family n=3 T...   233   4e-60
UniRef50_A0BR54 Chromosome undetermined scaffold_122, whole geno...   233   5e-60
UniRef50_A0LH50 Nitrilase/cyanide hydratase and apolipoprotein N...   233   6e-60
UniRef50_A4J4S3 Nitrilase/cyanide hydratase and apolipoprotein N...   232   7e-60
UniRef50_C1B562 Putative hydrolase n=2 Tax=Actinomycetales RepID...   231   1e-59
UniRef50_B7G2G6 Predicted protein n=1 Tax=Phaeodactylum tricornu...   231   1e-59
UniRef50_Q65KK0 Methylthioribose recycling protein n=1 Tax=Bacil...   231   1e-59
UniRef50_A8LPZ9 Nitrilase/cyanide hydratase and apolipoprotein N...   231   1e-59
UniRef50_Q11146 UPF0012 hydrolase Rv0480c/MT0498 n=34 Tax=Actino...   231   1e-59
UniRef50_A6DN63 Nitrilase/cyanide hydratase and apolipoprotein N...   231   2e-59
UniRef50_Q2NAB0 Nitrilase 1 like protein n=3 Tax=Sphingomonadale...   231   2e-59
UniRef50_Q972X1 264aa long hypothetical beta-ureidopropionase n=...   231   2e-59
UniRef50_C8NJS3 Carbon-nitrogen hydrolase family protein n=16 Ta...   231   2e-59
UniRef50_Q47VH0 Hydrolase, carbon-nitrogen family n=1 Tax=Colwel...   231   2e-59
UniRef50_B6B254 Hydrolase in PqqF 5'region n=1 Tax=Rhodobacteral...   231   2e-59
UniRef50_A9B254 Nitrilase/cyanide hydratase and apolipoprotein N...   230   3e-59
UniRef50_A9UWV2 Predicted protein (Fragment) n=1 Tax=Monosiga br...   230   4e-59
UniRef50_D1VW19 Hydrolase C26A3.11 n=1 Tax=Peptoniphilus lacrima...   230   4e-59
UniRef50_UPI0001BC35FB amidohydrolase n=1 Tax=Butyrivibrio cross...   230   5e-59
UniRef50_A6UCF8 Nitrilase/cyanide hydratase and apolipoprotein N...   230   6e-59
UniRef50_B2HTJ8 Predicted amidohydrolase n=18 Tax=Acinetobacter ...   229   6e-59
UniRef50_C7CES6 Putative N-carbamyl-D-amino acid amidohydrolase ...   229   6e-59
UniRef50_Q4Q8W4 Nitrilase, putative n=7 Tax=Trypanosomatidae Rep...   229   7e-59
UniRef50_A6TPX2 Nitrilase/cyanide hydratase and apolipoprotein N...   229   7e-59
UniRef50_B0KGW5 N-carbamoylputrescine amidase n=60 Tax=Bacteria ...   229   7e-59
UniRef50_C1E770 Predicted protein (Fragment) n=1 Tax=Micromonas ...   229   8e-59
UniRef50_A7FDR9 Hydrolase, carbon-nitrogen family protein n=45 T...   229   9e-59
UniRef50_C7YHV7 Putative uncharacterized protein n=2 Tax=Nectria...   228   1e-58
UniRef50_Q15NS3 Nitrilase/cyanide hydratase and apolipoprotein N...   228   2e-58
UniRef50_C7LN61 Nitrilase/cyanide hydratase and apolipoprotein N...   228   2e-58
UniRef50_Q02J62 Putative N-carbamoylputrescine amidohydrolase n=...   228   2e-58
UniRef50_Q2N7J4 Hydrolase n=5 Tax=Sphingomonadales RepID=Q2N7J4_...   227   2e-58
UniRef50_Q2RWF2 Nitrilase/cyanide hydratase and apolipoprotein N...   227   3e-58
UniRef50_Q1QX75 Nitrilase/cyanide hydratase and apolipoprotein N...   227   3e-58
UniRef50_D1NXA0 Hydrolase, carbon-nitrogen family n=8 Tax=Entero...   227   3e-58
UniRef50_A4SNH5 Amidohydrolase family protein n=2 Tax=Proteobact...   227   3e-58
UniRef50_Q1QTM0 Nitrilase/cyanide hydratase and apolipoprotein N...   227   3e-58
UniRef50_C9D316 Hydrolase n=1 Tax=Silicibacter sp. TrichCH4B Rep...   226   5e-58
UniRef50_Q5UF08 Predicted amidohydrolase n=1 Tax=uncultured alph...   226   5e-58
UniRef50_C0ZEK3 Beta-alanine synthase n=59 Tax=Bacteria RepID=C0...   226   6e-58
UniRef50_B8D189 Nitrilase/cyanide hydratase n=1 Tax=Halothermoth...   226   7e-58
UniRef50_C7QZX4 Nitrilase/cyanide hydratase and apolipoprotein N...   225   9e-58
UniRef50_D2RHR5 Nitrilase/cyanide hydratase and apolipoprotein N...   225   9e-58
UniRef50_C9N4S0 Nitrilase/cyanide hydratase and apolipoprotein N...   225   1e-57
UniRef50_C1N8C1 Predicted protein n=1 Tax=Micromonas pusilla CCM...   225   1e-57
UniRef50_D1BL17 Nitrilase/cyanide hydratase and apolipoprotein N...   225   1e-57
UniRef50_A4J6K3 Nitrilase/cyanide hydratase and apolipoprotein N...   225   1e-57
UniRef50_C5BSY0 Hydrolase, carbon-nitrogen family n=1 Tax=Teredi...   225   1e-57
UniRef50_C5DKM8 KLTH0F05984p n=2 Tax=Saccharomycetaceae RepID=C5...   225   2e-57
UniRef50_A1SE99 Nitrilase/cyanide hydratase and apolipoprotein N...   224   2e-57
UniRef50_C4R2Y9 Nit protein n=1 Tax=Pichia pastoris GS115 RepID=...   224   2e-57
UniRef50_A8IKB0 Nitrilase/cyanide hydratase and apolipoprotein N...   224   2e-57
UniRef50_Q8VYF5 N-carbamoylputrescine amidase n=162 Tax=cellular...   224   2e-57
UniRef50_A4BGL8 Predicted amidohydrolase n=1 Tax=Reinekea blande...   224   3e-57
UniRef50_Q8TLM7 Carbon-nitrogen hydrolase n=2 Tax=Methanosarcina...   224   3e-57
UniRef50_Q6MPB5 Putative amidohydrolase n=1 Tax=Bdellovibrio bac...   224   3e-57
UniRef50_B8FEV8 Nitrilase/cyanide hydratase and apolipoprotein N...   224   3e-57
UniRef50_B7Q2J6 Carbon-nitrogen hydrolase, putative n=1 Tax=Ixod...   224   3e-57
UniRef50_D0XIR2 Nitrilase/cyanide hydratase and apolipoprotein N...   224   3e-57
UniRef50_C0F0M8 Putative uncharacterized protein n=1 Tax=Eubacte...   222   7e-57
UniRef50_A8ZSH3 Nitrilase/cyanide hydratase and apolipoprotein N...   222   8e-57
UniRef50_C7QHA6 Nitrilase/cyanide hydratase and apolipoprotein N...   222   9e-57
UniRef50_Q97IH6 Predicted amidohydrolase n=1 Tax=Clostridium ace...   222   9e-57
UniRef50_UPI000185C288 hydrolase n=1 Tax=Corynebacterium amycola...   222   1e-56
UniRef50_D2RK67 Nitrilase/cyanide hydratase and apolipoprotein N...   222   1e-56
UniRef50_Q220F6 Nitrilase/cyanide hydratase and apolipoprotein N...   222   1e-56
UniRef50_B0X5I4 Hydrolase n=5 Tax=Culicidae RepID=B0X5I4_CULQU        221   2e-56
UniRef50_P55176 UPF0012 hydrolase in pqqF 5'region n=22 Tax=Bact...   221   2e-56
UniRef50_B4D6H9 Nitrilase/cyanide hydratase and apolipoprotein N...   221   2e-56
UniRef50_C8RSM4 Carbon-nitrogen hydrolase n=3 Tax=Corynebacteriu...   221   2e-56
UniRef50_C9XNA8 Putative carbon-nitrogen hydrolase n=6 Tax=Clost...   221   2e-56
UniRef50_A8PU96 Putative uncharacterized protein n=1 Tax=Malasse...   221   2e-56
UniRef50_A7I641 Nitrilase/cyanide hydratase and apolipoprotein N...   220   4e-56
UniRef50_A6UC57 Nitrilase/cyanide hydratase and apolipoprotein N...   219   8e-56
UniRef50_Q46E33 Carbon-nitrogen hydrolase n=3 Tax=Methanosarcina...   219   8e-56
UniRef50_Q28TG7 Nitrilase/cyanide hydratase and apolipoprotein N...   219   8e-56
UniRef50_A5TTZ3 Possible amidohydrolase n=4 Tax=Fusobacterium Re...   219   9e-56
UniRef50_B7CB92 Putative uncharacterized protein n=1 Tax=Eubacte...   218   1e-55
UniRef50_UPI0001973219 Nitrilase/cyanide hydratase and apolipopr...   218   1e-55
UniRef50_C5L8W7 Putative uncharacterized protein n=2 Tax=Perkins...   218   2e-55
UniRef50_A8SQH9 Putative uncharacterized protein n=1 Tax=Coproco...   218   2e-55
UniRef50_A0BLB1 Chromosome undetermined scaffold_114, whole geno...   217   3e-55
UniRef50_Q9ZMC7 Putative n=14 Tax=Helicobacter RepID=Q9ZMC7_HELPJ     217   3e-55
UniRef50_A5GU42 Nitrilase-related protein n=1 Tax=Synechococcus ...   217   3e-55
UniRef50_A1RVM3 Nitrilase/cyanide hydratase and apolipoprotein N...   217   3e-55
UniRef50_A8MC40 Nitrilase/cyanide hydratase and apolipoprotein N...   217   3e-55
UniRef50_A6TL48 Nitrilase/cyanide hydratase and apolipoprotein N...   217   3e-55
UniRef50_Q1MYM0 Predicted amidohydrolase n=1 Tax=Bermanella mari...   217   4e-55
UniRef50_B1MI91 Hypothetical carbon-nitrogen hydrolase family pr...   216   4e-55
UniRef50_B0MXF9 Putative uncharacterized protein n=1 Tax=Alistip...   216   5e-55
UniRef50_Q04W18 Amidohydrolase n=4 Tax=Leptospira RepID=Q04W18_L...   216   7e-55
UniRef50_Q6AMZ4 Putative uncharacterized protein n=1 Tax=Desulfo...   216   7e-55
UniRef50_B1K4S5 Nitrilase/cyanide hydratase and apolipoprotein N...   216   8e-55
UniRef50_Q6BU62 DEHA2C13310p n=6 Tax=Saccharomycetales RepID=Q6B...   216   8e-55
UniRef50_A7H2U5 Carbon-nitrogen hydrolase n=5 Tax=Campylobactera...   216   8e-55
UniRef50_Q5KLT5 Nitrilase-like protein, putative n=2 Tax=Filobas...   215   1e-54
UniRef50_A0B689 Nitrilase/cyanide hydratase and apolipoprotein N...   215   2e-54
UniRef50_A3CTE8 Nitrilase/cyanide hydratase and apolipoprotein N...   215   2e-54
UniRef50_UPI0001AEF4A9 hypothetical protein SghaA1_01010 n=1 Tax...   214   3e-54

Sequences not found previously or not previously below threshold:

>UniRef50_P58054 UPF0012 hydrolase ybeM n=121 Tax=Proteobacteria RepID=YBEM_ECO57
          Length = 262

 Score =  361 bits (926), Expect = 2e-98,   Method: Composition-based stats.
 Identities = 260/262 (99%), Positives = 260/262 (99%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           MLVAAGQFAVTSVWEKNAEICASLMAQAAEND SLF LPEALLARDDHDADLSVKSAQLL
Sbjct: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLL 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ
Sbjct: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE
Sbjct: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
           HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
Sbjct: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240

Query: 241 VRQVRAQLPVLNNRRFAPPQLL 262
           VRQVRAQLPVLNNRRFAPPQLL
Sbjct: 241 VRQVRAQLPVLNNRRFAPPQLL 262


>UniRef50_C0Z4R2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z4R2_BREBN
          Length = 265

 Score =  307 bits (786), Expect = 3e-82,   Method: Composition-based stats.
 Identities = 95/263 (36%), Positives = 142/263 (53%), Gaps = 4/263 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADL-SVKSAQL 59
           M VA  Q   T    +N +  A  +A+A    A    LPE   A     + +   + A+ 
Sbjct: 1   MKVAIAQLTATMDKTQNLQKAADYIAKAKAAGADFVILPEMYSAPATPKSGVTPAEVAEK 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVAL-QAGNIVARYAKLHLYDA 116
           L+G F+  L   +  + +  +  +         RA+N  V L + G ++  Y K HLYDA
Sbjct: 61  LDGPFVSGLAELASEHGVYVVCGVFESIEGDENRAYNTTVFLGREGQLLHAYRKTHLYDA 120

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
           F+  ES  +  G+    ++E E  K+GLM CY++RFPE+A   ALQGA+IL +PA WV G
Sbjct: 121 FSYTESDFIAPGDNPYQVVETEFGKIGLMVCYEVRFPEIARQFALQGADILFVPAGWVAG 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
            +KE HW TL+ ARA++ T ++ AA + GN   G+S  +DP GV IA+A E   L++ E+
Sbjct: 181 AMKEDHWETLVRARAIENTMFVCAADQVGNIFAGRSMFVDPMGVVIASAGEEETLLVTEL 240

Query: 237 TPERVRQVRAQLPVLNNRRFAPP 259
              R+ +VR +LP + NRR    
Sbjct: 241 DVSRIERVRGKLPSVANRRAELY 263


>UniRef50_UPI0001924654 PREDICTED: similar to Nit protein 1 n=1 Tax=Hydra magnipapillata
           RepID=UPI0001924654
          Length = 303

 Score =  293 bits (751), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 79/272 (29%), Positives = 133/272 (48%), Gaps = 15/272 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  Q   T   E+N  IC  L+ ++ + +A +  LPE      ++  D SVK A+ LE
Sbjct: 27  RVAVCQMNSTDDKERNIRICTELINESYDKEAKIVFLPECFDYIAENKTD-SVKMAESLE 85

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPS---TPGRAWNMLVALQ-AGNIVARYAKLHLYD-- 115
           G+ +   +  +K   +   +         + G  +N  + +   G +V+ Y K+HL+D  
Sbjct: 86  GDIIKHYKNLAKEKSLWLSMGGFHEKCSTSDGSIFNSHIIINANGELVSVYRKVHLFDVD 145

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                ++ES  V  G +I   ++    K+GL+ CYDLRFPE+++     GA+IL  P+A+
Sbjct: 146 IPGTVLKESSYVTPGKKIEKPVDTPVGKIGLLCCYDLRFPEISIVNRQLGAQILTFPSAF 205

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW  LL ARA++  CY++AA + G  N      G + I+DP+G  +A   + 
Sbjct: 206 TF-TTGLAHWHVLLRARAIENQCYVIAAAQTGKHNDKRTSYGHALIVDPWGKVVAECEKE 264

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
             + +A +    V  +R  +PV  +RR+    
Sbjct: 265 NGVCVASIDLSLVDSIRESMPVFEHRRYDLYN 296


>UniRef50_Q28IE5 Omega-amidase NIT2 n=42 Tax=cellular organisms RepID=NIT2_XENTR
          Length = 276

 Score =  292 bits (749), Expect = 6e-78,   Method: Composition-based stats.
 Identities = 75/270 (27%), Positives = 121/270 (44%), Gaps = 15/270 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             ++  QF V+ V  +N      L+ +AA+  A + ALPE       +      + A+ +
Sbjct: 4   FRLSLVQFLVSPVKSENLNRACKLIKEAAQKGAQIVALPECF--NSPYGTKYFPEYAEKI 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD---- 115
            GE   RL + +K   +  I         G+ +N   V    G ++ ++ K+HL+D    
Sbjct: 62  PGESTERLSQVAKECGIYLIGGSIPEEDSGKLYNTCAVFGPDGTLLVKHRKIHLFDIDVP 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                QES  +  G+    + E    KVG+  CYD+RF ELA   + +G ++LV P A+ 
Sbjct: 122 GKIRFQESETLSPGDS-FSVFETPYCKVGVGICYDIRFAELAQLYSKKGCQLLVYPGAFN 180

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  L  ARALD   Y+  A    ++       G S I+ P+G  IA A    
Sbjct: 181 M-TTGPAHWELLQRARALDNQVYVATASPARDEKASYVAWGHSTIVSPWGEVIAKAGSEE 239

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            +I A++  E + ++R Q+P+   RR    
Sbjct: 240 TVISADIDLEYLAEIREQIPIRRQRRHDLY 269


>UniRef50_A7A823 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=A7A823_BIFAD
          Length = 277

 Score =  292 bits (749), Expect = 7e-78,   Method: Composition-based stats.
 Identities = 108/259 (41%), Positives = 153/259 (59%), Gaps = 1/259 (0%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M VA GQF VT   E N  I +   ++AA N   +  LPE L+AR D D   +   AQ +
Sbjct: 19  MKVAVGQFTVTEKPEHNINIISGFASEAARNHTRILLLPEGLIARSDDDPHYTADHAQTI 78

Query: 61  EGEFLGRLRRESKRNMMTTILTIHV-PSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           +G F+  LR  S+ N +  + T+H+   T    +N  + +  G I+  Y K+HLYDAF  
Sbjct: 79  DGPFVTALRGISEANNIAVMGTVHLHEDTVDLPYNCFLVIDHGRILLEYRKIHLYDAFGE 138

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +ES  +  G+E+ PL++++G K G+MTCYD+RFPELA   A+ GA+ LV+ AAW RG  K
Sbjct: 139 RESDSIAPGHEVPPLVDIDGWKFGVMTCYDIRFPELARRHAVAGADALVVSAAWARGEGK 198

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
             HW+TL  ARAL+ TCY++A  E    +IG S ++DP    +A + E   LI A++  +
Sbjct: 199 VDHWTTLCKARALENTCYLMACSEHSGHDIGHSMVVDPAARILAQSGERDELIYADLNRD 258

Query: 240 RVRQVRAQLPVLNNRRFAP 258
           R+  VR  LPVL NRR   
Sbjct: 259 RLEDVRRILPVLKNRRITL 277


>UniRef50_UPI000186DBB5 conserved hypothetical protein n=1 Tax=Pediculus humanus corporis
           RepID=UPI000186DBB5
          Length = 438

 Score =  291 bits (745), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 87/271 (32%), Positives = 141/271 (52%), Gaps = 15/271 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L+A  Q   T+  EKN +I  SL+ +A + +A +  LPEA        A+ ++  A+ L+
Sbjct: 6   LIAICQMTSTNDKEKNFQIVESLVTEAKKANAKIAFLPEACDFVGSSKAE-TITLAETLD 64

Query: 62  GEFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF-- 117
           G  + + +  +K   +   +  IH   T  + +N  + +   GNIV +Y+K+HL+D    
Sbjct: 65  GPLVAKYKNLAKSLKIWISLGGIHESYTKSKLYNTHLMINDQGNIVGKYSKIHLFDVEIP 124

Query: 118 ----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                + ES  V+ G  I   +      VGL  CYD+RF EL++  A  GA+IL  P+A+
Sbjct: 125 EQNVRLMESSYVEKGKSITNPISTPVGNVGLAICYDMRFSELSIVLARLGAQILTFPSAF 184

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW T+L ARA++T CY+VAA + G+ N      G S ++DP+G  IA  S+ 
Sbjct: 185 TFAT-GASHWETILKARAVETQCYVVAAAQVGSHNDKRTSWGHSMVVDPWGKIIAQCSDG 243

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           P + +  +    + +VR  +PV N+RR+   
Sbjct: 244 PGIAVTSININYLEKVRLSMPVWNHRRYDLY 274


>UniRef50_UPI000197C0D6 hypothetical protein PretD1_21713 n=1 Tax=Providencia rettgeri DSM
           1131 RepID=UPI000197C0D6
          Length = 263

 Score =  291 bits (745), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 93/263 (35%), Positives = 146/263 (55%), Gaps = 4/263 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLS-VKSAQL 59
           M +A  Q A +     N +     + +AA+  A L  LPE  +A    D+ +S    A+ 
Sbjct: 1   MKIAIAQLASSPDKALNLKKACEAIQKAAQGGADLVLLPEMFMAFVPADSGISYADVAEP 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVAL-QAGNIVARYAKLHLYDA 116
           ++G F+ +L + +++  +     I+   P+ P RA+N  + L + G ++  Y K HLYDA
Sbjct: 61  VDGPFVSQLAKAAQQYGIYVTCGIYESAPNEPKRAFNTTIMLNRQGELIYHYQKTHLYDA 120

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
           F+ QES  +   N     +E E  K+G++ CY+LRFPE+A    L GA+++++P AWV G
Sbjct: 121 FSYQESLNIIQSNNELKPVETEFGKIGVLVCYELRFPEVARKLTLAGADLILVPTAWVSG 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
           PLKE H+ TL+ ARAL+ T  + A  + GN  IG+S + D  GVTIA+A     L  AE+
Sbjct: 181 PLKEEHYQTLVKARALENTVPVCACDQTGNIFIGRSLVCDALGVTIASAGYDETLFFAEI 240

Query: 237 TPERVRQVRAQLPVLNNRRFAPP 259
           + +   + R +LP + NRR    
Sbjct: 241 STQHTAETREKLPCMQNRRPELY 263


>UniRef50_B9ZGS1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Natrialba magadii ATCC 43099 RepID=B9ZGS1_NATMA
          Length = 271

 Score =  290 bits (742), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 86/268 (32%), Positives = 136/268 (50%), Gaps = 17/268 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +AA Q       E N       + +AA+  A + +LPE        + +     A+ +
Sbjct: 4   FTIAACQMDSQDDKEANLTQALDFIDEAAQKGADVVSLPEMFSFMG--EKEAYSTHAEPV 61

Query: 61  EGEFLGRLRRESKRNMMTT-ILTIHVPSTPG-RAWNMLVALQA-GNIVARYAKLHLYDA- 116
            GE    L  ++  + +     +    +  G R +N  V +   G I A+Y K HL+D  
Sbjct: 62  PGETTAALADKATTHGLHVHSGSFFEKAGDGDRVYNTSVVIDPDGEIQAQYRKTHLFDVT 121

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  QES+ V  G++   ++E +    GL  CYDLRF EL  + A+QGAE+L +PAA
Sbjct: 122 IGDEVVTQESKHVAPGDD-VTVVETDLATFGLSVCYDLRFSELYRSMAMQGAEVLFVPAA 180

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++T CY+VAAG+ G+K     + G+S IIDP+G  I  AS+
Sbjct: 181 FTL-FTGKDHWLPLLKARAIETQCYVVAAGQIGDKPSSVPSFGKSVIIDPWGNVIRMASD 239

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
              ++ AEV  + + +VR ++P L ++R
Sbjct: 240 REEVVTAEVDLDYLAEVRQKIPCLEHKR 267


>UniRef50_Q9NQR4 Omega-amidase NIT2 n=88 Tax=Eukaryota RepID=NIT2_HUMAN
          Length = 276

 Score =  288 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 69/270 (25%), Positives = 123/270 (45%), Gaps = 15/270 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +A  Q  ++S+   N     S + +AA   A + +LPE       + A    + A+ +
Sbjct: 4   FRLALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECF--NSPYGAKYFPEYAEKI 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD---- 115
            GE   +L   +K   +  I         G+ +N   V    G ++A+Y K+HL+D    
Sbjct: 62  PGESTQKLSEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVP 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                QES+ +  G+  +   +    +VGL  CYD+RF ELA   A +G ++LV P A+ 
Sbjct: 122 GKITFQESKTLSPGDSFST-FDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFN 180

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  L  +RA+D   Y+  A    +        G S +++P+G  +A A    
Sbjct: 181 L-TTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEE 239

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           A++ +++  +++ ++R Q+PV   +R    
Sbjct: 240 AIVYSDIDLKKLAEIRQQIPVFRQKRSDLY 269


>UniRef50_Q7TQ94 Nitrilase homolog 1 n=6 Tax=Coelomata RepID=NIT1_RAT
          Length = 292

 Score =  288 bits (738), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 89/274 (32%), Positives = 137/274 (50%), Gaps = 18/274 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           LVA  Q   T   ++N + CA L+ +A    A L  LPEA      + A+  +  ++ L+
Sbjct: 13  LVAVCQVTSTPNKQENFKTCAELVQEATRLGACLAFLPEAFDFIARNPAETLL-LSEPLD 71

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG-----RAWNMLVALQ-AGNIVARYAKLHLYD 115
           G+ LG+  + ++   +   L              + +N  V L   G++VA Y K HL D
Sbjct: 72  GDLLGQYSQLARECGIWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGSVVASYRKTHLCD 131

Query: 116 A-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                   ++ES     G  + P ++    KVGL  CYD+RFPEL+L  A  GAEIL  P
Sbjct: 132 VEIPGQGPMRESNYTMPGYALEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYP 191

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA 225
           +A+        HW  LL ARA+++ CY++AA +CG  +      G S ++DP+G  +A+ 
Sbjct: 192 SAFGS-VTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPWGTVVASC 250

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           SE P L +A +    ++Q+R  LPV  +RR    
Sbjct: 251 SEGPGLCLARIDLHFLQQMRQHLPVFQHRRPDLY 284


>UniRef50_Q86X76 Nitrilase homolog 1 n=34 Tax=Eumetazoa RepID=NIT1_HUMAN
          Length = 327

 Score =  284 bits (727), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 91/274 (33%), Positives = 131/274 (47%), Gaps = 18/274 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           LVA  Q   T   ++N + CA L+ +AA   A L  LPEA        A+ ++  ++ L 
Sbjct: 48  LVAVCQVTSTPDKQQNFKTCAELVREAARLGACLAFLPEAFDFIARDPAE-TLHLSEPLG 106

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG-----RAWNMLVALQ-AGNIVARYAKLHLYD 115
           G+ L    + ++   +   L              + +N  V L   G +VA Y K HL D
Sbjct: 107 GKLLEEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCD 166

Query: 116 A-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                   + ES     G  +   +     K+GL  CYD+RFPEL+LA A  GAEIL  P
Sbjct: 167 VEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTYP 226

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA 225
           +A+        HW  LL ARA++T CY+VAA +CG  +      G S ++DP+G  +A  
Sbjct: 227 SAFGSIT-GPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARC 285

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           SE P L +A +    +RQ+R  LPV  +RR    
Sbjct: 286 SEGPGLCLARIDLNYLRQLRRHLPVFQHRRPDLY 319


>UniRef50_B9L3Z7 Hydrolase, carbon-nitrogen family protein n=8 Tax=Bacteria
           RepID=B9L3Z7_THERP
          Length = 279

 Score =  284 bits (727), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 87/272 (31%), Positives = 131/272 (48%), Gaps = 17/272 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +   Q    S   +N  +   L+ +AA   A L ALPE +        +L   +A+ +
Sbjct: 5   LRIGLVQMNSRSDKSENLAVAERLIEEAARQGAELVALPEYVNFLGPR--ELHEANAEPI 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPST--PGRAWNMLVAL-QAGNIVARYAKLHLYDA- 116
            G    R    ++R  +  +    +  +  PG+ +N  V     G I+A Y K+HL+D  
Sbjct: 63  PGPTTERFAALARRYGIYLLGGSILERSAIPGKYYNTSVLFAPDGEIIASYRKIHLFDVD 122

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                   ES  +  G+ +    EV G  VGL  CYDLRFPEL    AL GAE++++PAA
Sbjct: 123 LTGNVTSNESATILPGDRVVT-AEVAGHVVGLTICYDLRFPELYRLLALDGAELILVPAA 181

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +     K+ HW TLL ARA++  CY+ A  + G  +      G S + DP+G  IA A  
Sbjct: 182 FTLYTGKD-HWHTLLRARAIENQCYVAAPAQIGPHDPGQQCYGHSLVADPWGTVIAEAIN 240

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
              +++  +    +R+VRAQLP L NRR    
Sbjct: 241 RVGVVVTTLDFAYLREVRAQLPSLANRRPETY 272


>UniRef50_UPI000051A529 PREDICTED: similar to Nitrilase and fragile histidine triad fusion
           protein CG7067-PA n=2 Tax=Coelomata RepID=UPI000051A529
          Length = 304

 Score =  283 bits (726), Expect = 3e-75,   Method: Composition-based stats.
 Identities = 88/273 (32%), Positives = 127/273 (46%), Gaps = 17/273 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           LVA  Q   T+  EKN +    L  +A    AS+   PEA     D   D     AQ L 
Sbjct: 28  LVAVCQMTSTNDKEKNLQTVRELSEKAKHRAASIAFFPEACDYLADSKKDTIA-MAQTLN 86

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG---RAWNMLVALQA-GNIVARYAKLHLYD-- 115
           G  +   +  +K N +   L     +         N  + + + G IV+ Y K+HL+D  
Sbjct: 87  GSTVTSYKEIAKINKIWLSLGGIHEALDNNREHISNTHILINSEGEIVSTYRKIHLFDMD 146

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                  + ES  V  G +I P +     K+ L  CYD+RFPEL+ +    GAEIL  P+
Sbjct: 147 NKNTGVRLMESDYVLPGQKIEPPISTPIGKLALSICYDMRFPELSFSLRNMGAEILTYPS 206

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS 226
           A+        HW  LL ARA++T CY+VAA +    N      G + +IDP+G  IA  S
Sbjct: 207 AFTYQT-GAAHWEILLRARAIETQCYVVAAAQTSIHNKKRVSWGHAMVIDPWGSIIAQCS 265

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           E   +I+AE+    ++Q+R  +P  N+RR    
Sbjct: 266 EKTDIILAEIDLNLLKQIRQNMPCENHRRTDLY 298


>UniRef50_Q9HIW8 Nitrilase related protein n=2 Tax=Thermoplasma RepID=Q9HIW8_THEAC
          Length = 270

 Score =  283 bits (724), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 76/264 (28%), Positives = 132/264 (50%), Gaps = 4/264 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKS-AQL 59
           M VA  Q   ++  EKN E    L+ +A   ++ L   PE  +     D    +K+ ++ 
Sbjct: 1   MKVAVVQMESSTDREKNIEASYRLLEKA--KNSDLVVFPEYQIYAPAFDGKDDMKTISEP 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVALQAGNIVARYAKLHLYDAFA 118
           L+G+F+  +   ++      IL I   +    + +N  + +    ++ +Y KLHL+DAF 
Sbjct: 59  LDGKFVKSITEIARSESQKIILNIPERNQYNLKPFNTAIYIDELGLILKYRKLHLFDAFG 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +ES   + G+    +    G  +G++ CYDLRFPE A   AL GA++++  A W  G  
Sbjct: 119 FRESSVFEKGDARPAIFNGSGDPLGVLICYDLRFPEPARMLALDGAKLIIYQAGWFAGER 178

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K   W TLL ARA++   +++ A + G++  G S +I P+G  +A       +I  ++  
Sbjct: 179 KYDQWKTLLKARAMENGVFVIGAAQTGHRFTGHSMVISPYGDVLAEMGTDEGVITFDIDF 238

Query: 239 ERVRQVRAQLPVLNNRRFAPPQLL 262
             V + R ++PVL +RR     +L
Sbjct: 239 SLVEKYREEVPVLKHRRTDVYDVL 262


>UniRef50_A9A651 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Thaumarchaeota RepID=A9A651_NITMS
          Length = 268

 Score =  282 bits (723), Expect = 7e-75,   Method: Composition-based stats.
 Identities = 82/259 (31%), Positives = 141/259 (54%), Gaps = 4/259 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQ 58
           M  A  QF  ++  E N +   S + +AA  +A+L A PE                  A+
Sbjct: 1   MKAAVVQFKASTNKETNLKKIISFIEKAASKNATLCAFPEFMMFYTNSSQTPKQLATLAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTP-GRAWNMLVALQA-GNIVARYAKLHLYDA 116
            + G F+  +   +K N +  + + +  S    R ++    +   G +++ Y K+HLYDA
Sbjct: 61  TINGNFVNTIANTAKENHVQVVGSFYEKSRKKDRVYDTSFVIDKTGKVISTYRKIHLYDA 120

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
              +ES ++ +G++IA  ++    KVG+M CYDLRFPE++ + A  G+E+LV P+AWV+G
Sbjct: 121 LGFRESDKMASGSKIAKPVKTTIGKVGMMICYDLRFPEMSRSLAAAGSEVLVAPSAWVKG 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
            +KE HW T+   RA++  CY++A  + GN   G+S ++DP+G  +    +   +    +
Sbjct: 181 NMKEEHWITINKTRAIENGCYVIAPDQVGNIYCGRSLVVDPYGKILLDMKKKQGIGYVNI 240

Query: 237 TPERVRQVRAQLPVLNNRR 255
             ++V+Q+R  LP+L NRR
Sbjct: 241 DLKKVKQIRKVLPLLKNRR 259


>UniRef50_A1HPP3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HPP3_9FIRM
          Length = 259

 Score =  281 bits (719), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 76/263 (28%), Positives = 128/263 (48%), Gaps = 14/263 (5%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q   V    E N +   +++ Q A+  A LF LPE       +  D  +K  + 
Sbjct: 1   MKVALLQMDIVLGDVEANRQKALAMLEQGAKAGAKLFVLPELWTTG--YVLDQLLKIGEP 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
             G  +  L++ +K N +  +         G+ +N +  + + G +V +Y+K+HL     
Sbjct: 59  DGGPTVKMLQQFAKDNGVEIVGGSIAEIRDGKVYNTIYVIDSAGEVVGKYSKIHL--VPM 116

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E + +  G+    L ++   K G + CYDLRF EL  A AL+GAE+L +PA W    +
Sbjct: 117 MDEEKYLTPGDRQG-LFDLSFGKAGGIVCYDLRFTELTRALALKGAEVLFIPAEWPA--I 173

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASE-MPALIM 233
           +  HW  L  ARA++   ++VA    G        G S ++ P+G  +A  SE    +I+
Sbjct: 174 RGRHWLILSQARAIENQMFVVAVNRVGRDHNNTFFGHSLVVSPWGEVLAEGSETEEQVII 233

Query: 234 AEVTPERVRQVRAQLPVLNNRRF 256
           A++    V ++R ++PV  +RR 
Sbjct: 234 ADIDLGMVPEIRRKVPVFADRRP 256


>UniRef50_UPI00019771AF Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Bifidobacterium bifidum NCIMB 41171
           RepID=UPI00019771AF
          Length = 296

 Score =  280 bits (717), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 120/288 (41%), Positives = 164/288 (56%), Gaps = 27/288 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  QF V    E N +I      QAA+  A L  LPE L+ARD  D   +   AQ L
Sbjct: 7   LKVAVAQFTVRREPEWNLDIIDGYAWQAADAGARLLVLPEGLIARDGDDDMFAAAHAQPL 66

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP--------------STPGRAWNMLVALQAGNIVA 106
           +G F   LRR S+   +T + T+H                +T  R  N+ V +  G ++A
Sbjct: 67  DGPFATGLRRISEERHITLMGTVHAVPGAADAVPDKPASCATDSRVSNVFVVIHDGALIA 126

Query: 107 RYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI 166
            Y KLHLYDAFA +ES  V +G E+ P++E++G  VG+MTCYD+RFPE+A + A++GA++
Sbjct: 127 TYRKLHLYDAFAARESDTVRSGTELPPIVEIDGWHVGVMTCYDVRFPEVARSLAVRGADV 186

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAAS 226
           +++ AAWVRG LKE HW  + AARAL+ TCY++A  E   +NIG SR IDP G  IA A 
Sbjct: 187 IIVSAAWVRGRLKERHWKLMTAARALENTCYVLACSEVSARNIGCSRAIDPLGEVIAQAG 246

Query: 227 EMPA-------------LIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +                +++A +  E +   R  LPVL NRRFA PQL
Sbjct: 247 DGQGWLCGQGEAGGQAGMLIARLHREVLESARRTLPVLENRRFADPQL 294


>UniRef50_C8VW38 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Clostridia RepID=C8VW38_DESAS
          Length = 285

 Score =  279 bits (714), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 76/276 (27%), Positives = 125/276 (45%), Gaps = 18/276 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              A  Q  V+     N     S++ +A    A L  +PE      ++       +    
Sbjct: 3   FKTAVCQMLVSHSKSDNISKAKSMIEEAVSQGAELIIMPEMFNCPYEN-TSFPDFAESYP 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP---GR-AWNMLVALQA-GNIVARYAKLHLYD 115
           +GE +  L + +K N +  +      S     GR  +N        G ++ R+ K+HL+D
Sbjct: 62  DGETVKFLAQTAKENKIYLVGGSVPESAETESGRQIFNTSFFFDPQGQLIVRHRKVHLFD 121

Query: 116 -----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                  + +ES  +  G++I  +   +   +GL  CYD+RFPEL  A  L+GA+++++P
Sbjct: 122 IDIEGGISFRESDTLGRGDQIT-VAGTKWCDIGLAICYDMRFPELMRAMVLKGAKMILIP 180

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAA 225
           AA+        HW   L  RA+D   +++AA    N        G S I+DP+G  +A A
Sbjct: 181 AAFNT-TTGPAHWEITLKTRAVDNQTFVIAASPARNLEAAYHAYGHSLIVDPWGEILAEA 239

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
                +I A +  E V +VR QLP+L +RR    +L
Sbjct: 240 GTGEEIIYASIDLELVDRVRRQLPLLRHRRTDLYRL 275


>UniRef50_A9WV78 Hydrolase, carbon-nitrogen family n=3 Tax=Micrococcaceae
           RepID=A9WV78_RENSM
          Length = 268

 Score =  277 bits (709), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 104/258 (40%), Positives = 142/258 (55%), Gaps = 2/258 (0%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M V+ GQF+     + N E    L A+AA++ + L   PE  +      A     +    
Sbjct: 1   MKVSVGQFSPVGDVDGNIEAMRRLAAEAAQDGSELILFPEEAMFTLGKVAGDFRSAVDAG 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
              F+ +L   +  + +  I   +  S   R +N LVA+   G I+  Y KLHLYDAF+ 
Sbjct: 61  WSVFVQQLTLIAAEHKIAIIAGGYESSGEERPFNTLVAVGSDGAILGTYRKLHLYDAFSY 120

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           QES+R+  GN    ++ V  + VG+MTCYDLRFPELA A A Q  +++ +PAAW +G  K
Sbjct: 121 QESKRIMPGNSGLTVVRVGELNVGMMTCYDLRFPELARALAEQDVDLICVPAAWFKGEHK 180

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPA-LIMAEVTP 238
             HW TLL ARA++ TC++ AAG      IG S I+DP GV  A   E P  L  AEVT 
Sbjct: 181 VDHWETLLKARAIENTCWVAAAGSMSPHCIGHSVILDPMGVPAAFLDEEPESLATAEVTV 240

Query: 239 ERVRQVRAQLPVLNNRRF 256
           +R+ +VR  LPVL NRR 
Sbjct: 241 KRIEEVREFLPVLKNRRI 258


>UniRef50_C1TRG7 Predicted amidohydrolase n=1 Tax=Dethiosulfovibrio peptidovorans
           DSM 11002 RepID=C1TRG7_9BACT
          Length = 274

 Score =  276 bits (707), Expect = 5e-73,   Method: Composition-based stats.
 Identities = 83/270 (30%), Positives = 131/270 (48%), Gaps = 15/270 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VAA Q       E N     +++ +A +  ASL   PE                A+ + 
Sbjct: 5   TVAAAQMDSGPEKEINLIHMETMIEEAGKRGASLVVFPE-TSTLLPSSGIEKEAGAEPVP 63

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYD--- 115
           G    RL + ++   +       +    G  + +N  V +   G + A+Y K+HL+D   
Sbjct: 64  GPSTDRLSKAAREAGIWVHSGSLLERIEGNEKCYNTSVLISPEGEVTAKYRKIHLFDVNV 123

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               +++ES    +GNEI  + E     +G+  CYDLRFPEL    AL+GA++LV+PA +
Sbjct: 124 HDGPSVRESASYASGNEIV-IAETPLGNIGMSICYDLRFPELYRILALRGAQVLVVPACF 182

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMP 229
                KE HW  LL ARA++  CY+VA G+ G+    +  G+S ++DP+G   A  +   
Sbjct: 183 TSDTGKE-HWDPLLRARAIENLCYVVAPGQVGSKPRYRAHGKSMVVDPWGTVTACRASGE 241

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            L++AEV  +R+  +R  +P L NRR    
Sbjct: 242 GLVLAEVDLDRLESLRHSVPCLQNRRPDTY 271


>UniRef50_Q2QQ94 Os12g0502500 protein n=5 Tax=Spermatophyta RepID=Q2QQ94_ORYSJ
          Length = 323

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 81/271 (29%), Positives = 127/271 (46%), Gaps = 19/271 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            V   Q       + N   C+ L  +AA +       PE        D + S+K A+ L+
Sbjct: 47  RVGVVQMTSVGDLDANYATCSRLAKEAASSGVKFLCFPEVFSFIGSKDGE-SIKIAEPLD 105

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYDA-- 116
           G  + R    +K + M   L       P     +N  V +   G I + Y K+HL+D   
Sbjct: 106 GPIMQRYCSLAKESSMWLSLGGFQEKGPDDSHQYNTHVLIDDSGEIRSSYRKIHLFDVDV 165

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQG-AEILVLPAA 172
                 +ESR   AG+ +  + +    ++GL  CYDLRFPEL      +  A++L++P+A
Sbjct: 166 PGNMVYKESRFTTAGDTVVAV-DSPFGRLGLTVCYDLRFPELYQCLRFKHQAQVLLVPSA 224

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW  LL ARA++T CY++AA + G  N      G S IIDP+G  IA   +
Sbjct: 225 FTK-VTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDSIIIDPWGTVIARLPD 283

Query: 228 M--PALIMAEVTPERVRQVRAQLPVLNNRRF 256
                  +A+V   +V  VR ++P+  +R+F
Sbjct: 284 RLSTGFAVADVDLSKVEAVRTKMPISEHRKF 314


>UniRef50_C6CYG4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Bacillales RepID=C6CYG4_PAESJ
          Length = 270

 Score =  273 bits (699), Expect = 4e-72,   Method: Composition-based stats.
 Identities = 77/267 (28%), Positives = 124/267 (46%), Gaps = 15/267 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAEN--DASLFALPEALLARDDHDADLSVKSA 57
           + +A  Q  +     E N    +S++ +AA       +   PE       +        A
Sbjct: 11  LRIALLQMNIEVGQPEANFSKLSSMLEEAASQPNKPDVIVFPEMWNTG--YALTEITTLA 68

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLV-ALQAGNIVARYAKLHLYDA 116
                     L   S+++ +  I            +N +    + GN +  Y+K+HL+  
Sbjct: 69  DPNGERTKAYLTEFSRKHGIHIIAGSIAEGREDGVYNTIYAFDREGNQIGDYSKIHLFRL 128

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
             + E + + AG+++  L E+EG   G+M CYD+RFPELA   AL GA++L +PA W   
Sbjct: 129 --MDEEKYLAAGDKLGKL-EIEGAGAGMMICYDIRFPELARKLALDGAKLLFVPAEWPHP 185

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALI 232
            L  HHW TLL ARA++   +++A    G        G S ++DP+G TIA A E   ++
Sbjct: 186 RL--HHWRTLLTARAIENQMFVIACNRVGISGDTHFFGHSMVLDPWGETIAEAGEEETIL 243

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPP 259
            AE+    V  VR ++PV  +RR +  
Sbjct: 244 YAEIDLSLVDTVRGKIPVFEDRRPSLY 270


>UniRef50_O76463 Nitrilase homolog n=6 Tax=Bilateria RepID=NFT1_CAEEL
          Length = 440

 Score =  272 bits (696), Expect = 9e-72,   Method: Composition-based stats.
 Identities = 79/273 (28%), Positives = 130/273 (47%), Gaps = 16/273 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q    +  EKN +   +++ +A E    +  LPE       +  +  +  A   + 
Sbjct: 17  IAVCQMTSDNDLEKNFQAAKNMIERAGEKKCEMVFLPECFDFIGLNKNEQ-IDLAMATDC 75

Query: 63  EFLGRLRRESKRNMMTTILTI---HVPSTPGRAWNMLVALQAGNIV-ARYAKLHLYD--- 115
           E++ + R  ++++ +   L       PS     WN  + + +  +  A Y KLHL+D   
Sbjct: 76  EYMEKYRELARKHNIWLSLGGLHHKDPSDAAHPWNTHLIIDSDGVTRAEYNKLHLFDLEI 135

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                + ES    AG E+ P ++    ++GL  CYD+RFPEL+L    +GA++L  P+A+
Sbjct: 136 PGKVRLMESEFSKAGTEMIPPVDTPIGRLGLSICYDVRFPELSLWNRKRGAQLLSFPSAF 195

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW TLL ARA++  CY+VAA + G  N      G S ++DP+G  +A  SE 
Sbjct: 196 TLNT-GLAHWETLLRARAIENQCYVVAAAQTGAHNPKRQSYGHSMVVDPWGAVVAQCSER 254

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             +  AE+    V  +R   PV ++RR     L
Sbjct: 255 VDMCFAEIDLSYVDTLREMQPVFSHRRSDLYTL 287


>UniRef50_A5N8H1 Predicted hydrolase n=3 Tax=Clostridium RepID=A5N8H1_CLOK5
          Length = 275

 Score =  271 bits (694), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 69/276 (25%), Positives = 124/276 (44%), Gaps = 19/276 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +   Q  V  S    N +     + +AA     + ALPE       ++     + A+ 
Sbjct: 1   MKIGLCQMMVLKSSKSDNVKRAKEAIYKAANKGTDIVALPEMFNCY--YNTKYFREYAEK 58

Query: 60  LE--GEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD 115
            +  GE L  L   +K   +  +   I      G  +N   V  + G ++ ++ K+HL+D
Sbjct: 59  DDCKGETLSMLSSAAKEMGIYIVGGSIPEIDDKGNIYNTSFVFNEKGELIGKHRKMHLFD 118

Query: 116 -----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                    +ES  +  G++   +++ +  K+G+  CYD+RFPEL    ALQGA+I+ +P
Sbjct: 119 IDIKDKITFKESNVLTPGDK-VTVIDTKWGKIGVAICYDVRFPELMRLMALQGAKIIFIP 177

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAA 225
           A++        HW  L  + A++   Y V      N N      G S ++DP+G  +   
Sbjct: 178 ASFNT-TTGPSHWELLFRSAAVENQLYTVGISPARNINYSYVAYGNSLVVDPWGKILNIL 236

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            E   ++++E+  E + +VR  +PV  +RR    ++
Sbjct: 237 DEKEGILLSEIDLEYIYEVRKSIPVFEHRREDLYEI 272


>UniRef50_B0SIF2 Amidohydrolase n=3 Tax=Bacteria RepID=B0SIF2_LEPBA
          Length = 269

 Score =  271 bits (694), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 78/270 (28%), Positives = 123/270 (45%), Gaps = 17/270 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              A  Q   T+    N   C   + +AA   A +  LPE            S+     +
Sbjct: 3   FKAAVVQVTSTARVSNNLTKCRQFVEEAARAGAKVIGLPENFSFMGSESEKQSLLG--QI 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP-GRAWNMLVALQA-GNIVARYAKLHLYD--- 115
           E E +  L+  +    +  +        P G+ +N  V +   G  V RY K+HL+D   
Sbjct: 61  EDETILFLKETASELGIYLLGGGFPTKAPSGKVFNTAVMINPKGEEVFRYHKVHLFDAVV 120

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
              F  +ES   ++G ++  +++ E  K+    CYDLRFPEL  A + QG ++  LPAA+
Sbjct: 121 GDGFPYKESNHTESGEKVPEVIQTEYGKISSAICYDLRFPELFRALSKQGVDLCFLPAAF 180

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-------IGQSRIIDPFGVTIAAAS 226
              P  E HW  LL ARA++   Y++A G+ G  +        G S II P+G  +A   
Sbjct: 181 TV-PTGEAHWHVLLRARAIENLMYVLAPGQTGTHDPHGKRKTFGHSLIISPWGEILAELD 239

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
                 +A +  E++ ++R  LP LN+R+F
Sbjct: 240 HEEGFAIATMEMEKLSEIRNTLPSLNHRKF 269


>UniRef50_Q0S3S2 Possible amidohydrolase, carbon-nitrogen hydrolase family protein
           n=11 Tax=Actinomycetales RepID=Q0S3S2_RHOSR
          Length = 265

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 101/262 (38%), Positives = 143/262 (54%), Gaps = 3/262 (1%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  QFA     ++N     +L A+AA   A +   PE  +       +  V+SA+ L+G
Sbjct: 4   VAVIQFAPGQDKQENLRTLRTLAAEAAGRGAKVVVAPEYAMFTAPRTDERIVESAEGLDG 63

Query: 63  EFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNMLVALQAGN-IVARYAKLHLYDAFAIQ 120
           EF+  L   +K   +  +  ++          N +VAL  G  IVA Y KLHLYDAF  +
Sbjct: 64  EFVSGLAATAKELDVHLVAGVNEHLPGDDHISNTIVALGPGGDIVATYRKLHLYDAFGYK 123

Query: 121 ESRRVDAGN-EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           ES  + AG  +      V+G+  G+ TCYDLRFPE+       GA++L+LPA WV GPLK
Sbjct: 124 ESDVIRAGEIDAPQTFAVDGLTFGMQTCYDLRFPEVTRRIVDAGADVLLLPAQWVPGPLK 183

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
           E HWSTL+ ARA++ T Y+ AA +      G S I+DP GVT+A+  E     +A V+ E
Sbjct: 184 EDHWSTLVRARAIENTVYVAAADQSARTGAGNSMIVDPMGVTLASLGERVGTAVAAVSAE 243

Query: 240 RVRQVRAQLPVLNNRRFAPPQL 261
           R+ +VR + P L  RRF   ++
Sbjct: 244 RITEVREKNPALALRRFTVSEI 265


>UniRef50_D2R0U8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R0U8_9PLAN
          Length = 292

 Score =  270 bits (690), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 96/268 (35%), Positives = 140/268 (52%), Gaps = 18/268 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q   T     N     +L+ QAA   A L  LPE  ++  D     +V  AQ L G
Sbjct: 9   VAAIQMRATDDVAANFATAVTLVGQAAAAGARLVVLPELFVSYGDLARTAAV--AQSLLG 66

Query: 63  EFLGRLRRESKRNMMTTILTIHVP--STPGRAWNMLVALQA-GNIVARYAKLHLYDAF-- 117
            ++  L++ +K   +  +        +   RA+N    +   G IVA Y K+HL+D    
Sbjct: 67  TWITELQQLAKSKNIWLVAGSIPEQVANDQRAYNCSTVISPTGEIVAAYRKIHLFDVEIA 126

Query: 118 ---AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              A QES  +  GNE+  +++++  +VG+  CYDLRFPEL    A  GAE++V+PAA+ 
Sbjct: 127 GRVASQESLHLLPGNELV-VVKIDDWQVGIAICYDLRFPELFRNLATLGAELVVIPAAFT 185

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAA-ASEM 228
           R    + HW  L+  RALD   Y+VAA + G+ N      G S I++P+G  IA   SE 
Sbjct: 186 R-TTGKDHWDLLVRTRALDAQAYIVAANQGGDHNGQSSSYGHSMIVEPWGKVIAQIDSED 244

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
             ++ + +  +RV +VR QLPVL NRR 
Sbjct: 245 EGIVFSSIDRKRVAEVRRQLPVLRNRRL 272


>UniRef50_Q8RUF8 AT5g12040/F14F18_210 n=16 Tax=Eukaryota RepID=Q8RUF8_ARATH
          Length = 369

 Score =  270 bits (690), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 75/276 (27%), Positives = 118/276 (42%), Gaps = 20/276 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE- 61
           +   Q +VTS  ++N       + +AA   A L  LPE   +   +D+      A+ ++ 
Sbjct: 90  IGLCQLSVTSDKKRNISHAKKAIEEAASKGAKLVLLPEIWNSPYSNDS--FPVYAEEIDA 147

Query: 62  ----GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYD- 115
                     L   SKR  +T I          R +N        G + A++ K+HL+D 
Sbjct: 148 GGDASPSTAMLSEVSKRLKITIIGGSIPERVGDRLYNTCCVFGSDGELKAKHRKIHLFDI 207

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                    ES+ + AG E   +++ +  ++G+  CYD+RF ELA+  A +GA +L  P 
Sbjct: 208 DIPGKITFMESKTLTAG-ETPTIVDTDVGRIGIGICYDIRFQELAMIYAARGAHLLCYPG 266

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAAS 226
           A+        HW  L  ARA D   Y+           G    G S ++ PFG  +A   
Sbjct: 267 AFNM-TTGPLHWELLQRARATDNQLYVATCSPARDSGAGYTAWGHSTLVGPFGEVLATTE 325

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
              A+I+AE+    + Q R  LP+   RR    QL+
Sbjct: 326 HEEAIIIAEIDYSILEQRRTSLPLNRQRRGDLYQLV 361


>UniRef50_Q702A9 Putative predicted amidohydrolase n=6 Tax=Archaea
           RepID=Q702A9_9CREN
          Length = 285

 Score =  268 bits (686), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 76/262 (29%), Positives = 129/262 (49%), Gaps = 7/262 (2%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
              A  Q   +   E N      L+ +AA+  A L   PE  +A        +   + A+
Sbjct: 8   FRAAIVQMKSSEEKEHNLAYSVKLINEAAKRKARLICFPEFQMAYSPAEQKTESLHRIAE 67

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHV----PSTPGRAWNMLVALQA-GNIVARYAKLHL 113
            + G F+  L   +++N +  I T++          + ++  + +   G + + Y K+HL
Sbjct: 68  KICGNFVSTLSNSARQNKINVIATMYEIINANEKSQKVFDTGIIINELGKVQSIYRKVHL 127

Query: 114 YDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
           YDA   +ES+++ AG+ I    +     +GL+ CYD+RFPE++    + GA ILV P+AW
Sbjct: 128 YDALGFKESKKLLAGSIIEKPSKTSVGNLGLLICYDMRFPEISRILTVNGANILVSPSAW 187

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIM 233
           V G +K+ HW  ++ ARA++   Y++A  + GN   G S  IDPFG T+        +  
Sbjct: 188 VAGFMKKVHWEVMVRARAIENGVYVLAPNQVGNIYCGHSMAIDPFGATVLDMKNRQGIEY 247

Query: 234 AEVTPERVRQVRAQLPVLNNRR 255
            ++   ++   R  LP+L NRR
Sbjct: 248 VDIDTAKIDTTRRTLPLLMNRR 269


>UniRef50_O76464 Nitrilase homolog n=6 Tax=Sophophora RepID=NFT1_DROME
          Length = 460

 Score =  267 bits (684), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 77/265 (29%), Positives = 122/265 (46%), Gaps = 13/265 (4%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            +A GQ   TS    N      L+ +A   +A +  LPE      +     +++ ++ L+
Sbjct: 34  TIAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVGESRTQ-TIELSEGLD 92

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA-- 118
           GE + + R  +K N +   L         + +N  V L   G + A Y KLH++D     
Sbjct: 93  GELMAQYRELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTTKE 152

Query: 119 --IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
             ++ES  V  G  +   +     ++GL  CYDLRF E A+     GA +L  P+A+   
Sbjct: 153 VRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYA 212

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMP-A 230
             K  HW  LL ARA++T C++VAA + G  N      G S I+ P+G  +A  SE    
Sbjct: 213 TGK-AHWEILLRARAIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELD 271

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRR 255
           +  AEV    ++ +   +P   +RR
Sbjct: 272 IGTAEVDLSVLQSLYQTMPCFEHRR 296


>UniRef50_D1Y612 Hydrolase n=2 Tax=Bacteria RepID=D1Y612_9BACT
          Length = 274

 Score =  267 bits (683), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 86/268 (32%), Positives = 129/268 (48%), Gaps = 21/268 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL-L 60
           L+A  Q       + N +     + +AA   A   + PE       +  D   ++ +L  
Sbjct: 5   LMAVIQMDTRDNKDANLKAACDFIDEAASKGAKFVSFPEVF-----NVIDEGQEAPELVP 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHV---PSTPGRAWNMLVALQAGNIVARYAKLH----- 112
           EG  +  +  +++R+ +           P    +     V    G +VA+Y KLH     
Sbjct: 60  EGRTISLMAEKARRHNLWIHCGSIAEVNPEGDRKFNTTAVLNPQGRMVAKYRKLHTFDIT 119

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
           L D    +ES R+  G E+    + E   +GL  CYD+RFPEL    AL GA+IL  PA 
Sbjct: 120 LPDGSVAEESARIKPGREMVT-ADTEMGCLGLSICYDIRFPELYRYLALHGAQILFAPAN 178

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +     K+ HW  +L ARA++ TCY+VAAG+ G K+      G S IIDP+G  +A ASE
Sbjct: 179 FRMATGKD-HWEAILRARAIENTCYVVAAGQYGKKHGTSDSFGNSMIIDPWGTVVARASE 237

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
              L + E+  + + +VR+ LP L NRR
Sbjct: 238 GAGLAVGEIDLDYLDKVRSHLPSLKNRR 265


>UniRef50_B2J6W4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=11 Tax=Cyanobacteria RepID=B2J6W4_NOSP7
          Length = 270

 Score =  267 bits (682), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 87/269 (32%), Positives = 132/269 (49%), Gaps = 17/269 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L AA Q        KN      L+  A    A L  LPE      +    L+   A  LE
Sbjct: 5   LAAAIQLTSVPDLHKNLAQAEELIELAVRRGAELVGLPENFSYMGEEKDKLAQGDAIALE 64

Query: 62  GEFLGRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
            E    L++ ++R  +T +           G+ +N  + +   G  ++RY K+HL+D   
Sbjct: 65  SE--KFLKKMAQRFQITILGGSFPLPVDNTGKVYNTTLLIDPSGQELSRYYKVHLFDVDV 122

Query: 116 --AFAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                 +ES  V AG ++ P+    +   +GL  CYD+RFPEL    A +GA+++ +PAA
Sbjct: 123 PDGNTYRESSTVVAGTQLPPVHFSEKLGNLGLSICYDVRFPELYRHLAEKGADVIFIPAA 182

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++ T Y++A  + GN        G + IIDP+GV +A A E
Sbjct: 183 FTA-FTGKDHWQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVIIDPWGVILADAGE 241

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            P + +AE+ P R+ QVR Q+P L +R F
Sbjct: 242 KPGIAIAEIKPTRLEQVRRQMPSLQHRVF 270


>UniRef50_B9HD27 Predicted protein n=8 Tax=Magnoliophyta RepID=B9HD27_POPTR
          Length = 370

 Score =  266 bits (681), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 70/278 (25%), Positives = 115/278 (41%), Gaps = 20/278 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +   Q +VT+  E+N       + +AA   A L  LPE   +   +  D     A+ +
Sbjct: 88  FKIGLCQLSVTADKERNIAHARKAIEEAAAKGAKLVMLPEIWNSPYSN--DCFPVYAEDI 145

Query: 61  E-----GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLY 114
           +           L   +    +T +       +  R +N   V    G + A++ K+HL+
Sbjct: 146 DAGGEASPSTAMLSEAAGLLKVTIVGGSIPERSGDRLYNTCCVFDSDGKLKAKHRKIHLF 205

Query: 115 D-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
           D          ES+ + AG E   +++ E  ++G+  CYD+RF ELA+  A +GA ++  
Sbjct: 206 DIDIPGKITFIESKTLTAG-ETPTIVDTEVGRIGIGICYDIRFQELAIIYAARGAHLICY 264

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAA 224
           P A+        HW  L  ARA D   Y+           G    G S ++ PFG  +A 
Sbjct: 265 PGAFNM-TTGPLHWELLQRARAADNQLYVATCSPARDVAAGYVAWGHSTLVGPFGEVLAT 323

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
                 +I+AE+    +   R  LP+   RR    QL+
Sbjct: 324 TEHEEDIIIAEIDYSLLEVRRTNLPLTKQRRGDLYQLV 361


>UniRef50_A4ALG5 Putative hydrolase n=1 Tax=marine actinobacterium PHSC20C1
           RepID=A4ALG5_9ACTN
          Length = 271

 Score =  266 bits (680), Expect = 7e-70,   Method: Composition-based stats.
 Identities = 93/259 (35%), Positives = 135/259 (52%), Gaps = 3/259 (1%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  QFA  +  ++N      L  +A E  A+    PE          D  + +A+ L+
Sbjct: 6   TVAVAQFAPGADRDENIATVTQLAERAVERGANFVVFPEYSAYFTPTMGDDWLAAAEPLD 65

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAW-NMLVALQA-GNIVARYAKLHLYDAFAI 119
           G F+  L   ++R  +     +   +   + + N LVA+   G +VA Y K HLYDAF  
Sbjct: 66  GPFVQALTSLAQRLRIHVAAGMLESADEEKRFSNTLVAIAPTGAVVATYRKQHLYDAFGQ 125

Query: 120 QESRRVDAGNEIAP-LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           +ES  V  G+  AP     EG  VGL TCYD+RFPE++      GA ++V+PA WVRGPL
Sbjct: 126 RESDWVIPGSIGAPETFTWEGFTVGLQTCYDIRFPEVSRRLVDAGANLIVVPAEWVRGPL 185

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           KE+HW TLL ARA++ T ++ AA       +G S ++DP GV +    E   + +A +  
Sbjct: 186 KEYHWRTLLTARAIENTIFVAAADHAPPIGVGHSMVVDPMGVELVTIGERTDVAVAHIEH 245

Query: 239 ERVRQVRAQLPVLNNRRFA 257
            R+ +VRA  P L  RR+ 
Sbjct: 246 SRLDEVRAINPALELRRYG 264


>UniRef50_P55175 UPF0012 hydrolase sll0601 n=46 Tax=Cyanobacteria RepID=Y601_SYNY3
          Length = 272

 Score =  265 bits (679), Expect = 8e-70,   Method: Composition-based stats.
 Identities = 88/268 (32%), Positives = 131/268 (48%), Gaps = 14/268 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSA-QLL 60
           L AA Q        +N +    L+  A    A L  LPE      +    L   +A    
Sbjct: 5   LAAALQMTSRPNLTENLQEAEELIDLAVRQGAELVGLPENFAFLGNETEKLEQATAIATA 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD---- 115
             +FL  + +  +  ++       V    G+A+N    +   G  +ARY K+HL+D    
Sbjct: 65  TEKFLQTMAQRFQVTILAGGFPFPVAGEAGKAYNTATLIAPNGQELARYHKVHLFDVNVP 124

Query: 116 -AFAIQESRRVDAGNEIAPLLEVE-GMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 ES  V AG +  P+   +    +GL  CYD+RFPEL    + QGA++L +PAA+
Sbjct: 125 DGNTYWESATVMAGQKYPPVYHSDSFGNLGLSICYDVRFPELYRYLSRQGADVLFVPAAF 184

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                K+ HW  LL ARA++ TCY++A  + G         G + IIDP+GV +A A E 
Sbjct: 185 TAYTGKD-HWQVLLQARAIENTCYVIAPAQTGCHYERRHTHGHAMIIDPWGVILADAGEK 243

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
           P L +AE+ P+R++QVR Q+P L +R F
Sbjct: 244 PGLAIAEINPDRLKQVRQQMPSLQHRVF 271


>UniRef50_Q2NHR0 Predicted amidohydrolase n=1 Tax=Methanosphaera stadtmanae DSM 3091
           RepID=Q2NHR0_METST
          Length = 274

 Score =  265 bits (679), Expect = 9e-70,   Method: Composition-based stats.
 Identities = 69/265 (26%), Positives = 116/265 (43%), Gaps = 13/265 (4%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +A  Q  V    + N E    L+ +A+ N A L  LPE      D+         +  
Sbjct: 4   FKIATCQMNVVDNKDTNIEHAIQLIKKASSNGAKLITLPEMFNTPYDNSK-FIEYCEEET 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA- 118
             + L  ++  ++   +               +N    +   G I+ ++ K+H++D    
Sbjct: 63  TSKTLNSMQDIAREENIYLQSGSIPEKESNHLYNTAYLINPKGKIIGKHRKMHMFDIDTD 122

Query: 119 ---IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
                ES  +  G+ +  + +     + +  CYD+RFPEL        ++I++LP A+ +
Sbjct: 123 NMKFTESDTLTPGDSVTTI-KTPLANISIAICYDIRFPELWTLMNKNNSDIILLPGAFNK 181

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPA 230
                 HW TL+ ARA+D  CY+VA      +N      G S I++P+G  IA A E   
Sbjct: 182 -TTGPLHWETLIKARAIDNQCYVVATSPSQIENPYYVAWGHSMIVNPWGKIIAKAHENEE 240

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRR 255
           ++ A +T   +  VR Q+PVL NRR
Sbjct: 241 ILYANITQSSLSSVRNQIPVLTNRR 265


>UniRef50_Q557J5 Nitrilase homolog 1 n=1 Tax=Dictyostelium discoideum
           RepID=NIT1_DICDI
          Length = 291

 Score =  265 bits (678), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 77/280 (27%), Positives = 132/280 (47%), Gaps = 22/280 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADL-SVKSAQLL 60
            +  GQ   T+  E N   C  ++ +A EN  +LF LPE             S  +A+ L
Sbjct: 14  RIGLGQITSTNNKEDNFRKCKEMIEKAVENKVNLFCLPECFAFISGGIHQFESRDNAEYL 73

Query: 61  E--GEFLGRLRRESKRNMMTTILTIHVP----STPGRAWNMLVALQ-AGNIVARYAKLHL 113
           +  G  + R +  +K+N +   L               +N  + +   G IV  Y K+HL
Sbjct: 74  DQKGGIIERYKDLAKQNNIWLSLGGFHEKILDDPNDMIYNTHLIIDSNGVIVCEYRKMHL 133

Query: 114 YD------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +D         + ES+ V  GN++  + +    K+GL  CYDLRFPEL L+     A+IL
Sbjct: 134 FDVDIPSKGVKMNESKVVKGGNDLV-VCDSPVGKLGLSICYDLRFPELYLSLRRMDAQIL 192

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTI 222
           ++P+A+++    E HW  LL ARA++   Y++AA + G+ +      G S IIDP+G  +
Sbjct: 193 LVPSAFMKST-GEAHWKPLLQARAIENQTYVIAAAQTGDHHSKRSSYGHSMIIDPWGKVL 251

Query: 223 AAASEM-PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
               +    +   ++  + +   R  +PV N+++    ++
Sbjct: 252 HDLPDNLNDIAFVDIDLDYISTCRENIPVFNHKKLNNYKI 291


>UniRef50_D2RIK2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Acidaminococcus RepID=D2RIK2_ACIFE
          Length = 275

 Score =  265 bits (677), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 84/274 (30%), Positives = 129/274 (47%), Gaps = 18/274 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            + AA Q         N       + +AA   A L  LPE   + +    D++ ++  + 
Sbjct: 4   FIAAAVQMDSQDDKMANLAAAERYIREAAARGARLVVLPE---SMNYIGRDMAQEAEAIP 60

Query: 61  EGEFLGRLRRESKRNMMTTILTI---HVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD- 115
            G    RL   ++   +           P  P R +N    +   G + A+YAKLH +D 
Sbjct: 61  GGPTFQRLSGLARELDLWLEAGSIYESNPEDPARPFNTTFLICPDGTLAAKYAKLHPFDV 120

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES RV  G ++  + E +  KVGL  CYD+RF E+    AL+GA++  +PA
Sbjct: 121 VLPNGVTSRESDRVCPGKKLT-VAETDLGKVGLGICYDIRFGEMFRIMALEGAKLFAVPA 179

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASE 227
            +     K+ HW  LL ARA++  CY++A  + G K      G S ++DP+G  IA AS+
Sbjct: 180 NFTVNTGKD-HWEVLLRARAIENECYVIAPNQMGKKPRFTAYGNSLMVDPWGTVIARASD 238

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            P +I AE+  + V +VR     L+NRR    QL
Sbjct: 239 KPGVITAEIDLDYVTKVRQSTFTLDNRRPDVYQL 272


>UniRef50_A2BNC1 Predicted amidohydrolase n=1 Tax=Hyperthermus butylicus DSM 5456
           RepID=A2BNC1_HYPBU
          Length = 269

 Score =  264 bits (675), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 85/266 (31%), Positives = 139/266 (52%), Gaps = 5/266 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAE--NDASLFALPEALLA-RDDHDADLSVKSA 57
           + +A  QF  T   E++ E    L+++     ++A L  +PE  +A       +     A
Sbjct: 4   LTIALLQFGATHSKEESLERIRKLISRYERIVSEADLLLVPEYSMADPTGQPPEAIAAIA 63

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNMLVALQA-GNIVARYAKLHLYD 115
           + LEG ++G   R ++   +  + T++  S   G+ +N    +   G ++A Y K+HL+D
Sbjct: 64  EPLEGPWIGFFARLAREYSVHVVATLYEKSKAGGKPYNTAALIAPTGELLAVYRKIHLFD 123

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
           A+  +ES     G E A L  ++G ++ L  C+DLRFPEL    ALQGAE++ +PAAW R
Sbjct: 124 AYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRFPELFRTYALQGAELVAVPAAWYR 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAE 235
           GP KE     + AARA + T Y+  A +  +   G+S + DP+G+ +  A     ++  E
Sbjct: 184 GPAKEDQLRIIAAARAHENTMYIAVASQYNSNFTGRSLVADPYGLVLLDAGRGEKIVQIE 243

Query: 236 VTPERVRQVRAQLPVLNNRRFAPPQL 261
           V  E + + R QLP+L  RR    +L
Sbjct: 244 VDRESLEEARRQLPLLKLRRPHAYKL 269


>UniRef50_Q7MHE3 Predicted amidohydrolase n=69 Tax=Proteobacteria RepID=Q7MHE3_VIBVY
          Length = 300

 Score =  263 bits (674), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 75/268 (27%), Positives = 122/268 (45%), Gaps = 15/268 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            +A  Q   TS    N         QAA   ASL   PE  L     + D    +  L  
Sbjct: 29  RIAIIQMTSTSDCTDNVAYIEHWAEQAALQGASLVVTPENALLFGGRE-DYHQHAEPLGN 87

Query: 62  GEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDA---- 116
           G     + + +KR  +T ++  + +          LV    G  +  Y+KLH++D     
Sbjct: 88  GPLQQAMAQLAKRLAVTLVIGSMPIRQGHDVTTTSLVFGPNGERLGHYSKLHMFDVEVSD 147

Query: 117 --FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ES    AG+  + ++     ++GL  CYD+RFP L      +GA+IL++PAA+ 
Sbjct: 148 GHGHYRESDSFLAGDR-SSVVATPIGRLGLSICYDVRFPALYQTLRQKGADILLVPAAFT 206

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASEMP 229
                E HW  LL ARA++  C+++AA + G      +  G S +IDP+G  +A   +  
Sbjct: 207 A-VTGEAHWEVLLRARAIENQCWVIAAAQGGMHSASRETWGHSMVIDPWGKVVAQLPQQG 265

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFA 257
            L++AE+       +R ++PV+ + RF 
Sbjct: 266 DLLLAEIDLALSDTIRRKMPVVKHSRFT 293


>UniRef50_B0MEV6 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0MEV6_9FIRM
          Length = 272

 Score =  263 bits (674), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 81/265 (30%), Positives = 124/265 (46%), Gaps = 5/265 (1%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           + A  Q   +   EKN         +A E  A     PE  +     +     + AQ L+
Sbjct: 4   IAAIAQCRASQEPEKNLCKAEFFCREAREESACFVIFPEYFMTYYPIEGSAYYEKAQTLD 63

Query: 62  GEFLGRLRRESKRNMMTTILTIHVP---STPGRAWNMLVALQA-GNIVARYAKLHLYDAF 117
           G F+  ++R +  +    +  +       + G+ +N  V L   GN+ + Y K HL+DAF
Sbjct: 64  GPFVQGMKRLAAAHGQWILFGMSEKPGRDSGGKCFNTAVLLDDRGNLCSVYRKTHLFDAF 123

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
           + +ES     G  +   +     K GL TCYDLRFPE A  QAL+GAE+L+ P+AWV GP
Sbjct: 124 SWKESDSTLPGEVLHEPVNTPLGKAGLGTCYDLRFPEPARIQALKGAEVLIYPSAWVDGP 183

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKNI-GQSRIIDPFGVTIAAASEMPALIMAEV 236
            K   W  LL ARA++ T + +       ++  G+S   DP G  +A       LI+  V
Sbjct: 184 DKFMQWEALLRARAIENTVFTIGCCHYSEEHYMGRSLAFDPSGRKLAEGEAGEELIVLPV 243

Query: 237 TPERVRQVRAQLPVLNNRRFAPPQL 261
             ++   +  Q+PV+ NRR     +
Sbjct: 244 DTDQRDAIIHQVPVMKNRRTDLYDI 268


>UniRef50_Q1PXD4 Similar to N-carbamoyl-D-amino acid hydrolase n=1 Tax=Candidatus
           Kuenenia stuttgartiensis RepID=Q1PXD4_9BACT
          Length = 277

 Score =  263 bits (674), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 81/266 (30%), Positives = 127/266 (47%), Gaps = 16/266 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +AA Q        KN      LM +A +  A L ALPE        + +    + +   G
Sbjct: 6   IAAIQMCSVHDRNKNLNTARVLMEKAVQKGARLIALPENFSFIG-QERENITFAEERETG 64

Query: 63  EFLGRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF-- 117
           E +  L++ S ++ +  I        S+  +  N  +    +G I+  Y K+HL+D    
Sbjct: 65  EIVHFLKKFSMKHSVAIIGGSVPLRSSSKAKVTNTCLVFDQSGVIIGSYDKIHLFDFHLD 124

Query: 118 ---AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ES  V  G  I  + ++ G  +GL  CYDLRFPEL     L+G E+L  P+A+ 
Sbjct: 125 DKTVYRESHYVKHGKHIETV-KLFGHIMGLCICYDLRFPELFRKLMLRGMEVLFAPSAFT 183

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMP 229
               K+ HW  LL ARA++  CY+VA  + G  N      G++ IIDP+G  +A   +M 
Sbjct: 184 METGKD-HWEILLRARAIENQCYVVAPAQYGRHNDERISYGRTMIIDPWGRIMAQCQDME 242

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRR 255
            +I+ E+    + +VR +LP L + R
Sbjct: 243 DVIVCEIDFAFLGEVRKRLPCLKHIR 268


>UniRef50_B6HUF1 Pc22g05380 protein n=28 Tax=Leotiomyceta RepID=B6HUF1_PENCW
          Length = 274

 Score =  263 bits (673), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 80/272 (29%), Positives = 130/272 (47%), Gaps = 15/272 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +L A GQ   TS    N   C  L+ +AA   A +  LPEA              +    
Sbjct: 2   VLAAVGQLCSTSNITSNLAQCKVLVRKAAAAGAKVLFLPEASDYIASSAEQSYSLAGSEE 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLY----- 114
              F+  L+R++    +   + IH  ++  R  N+L+ +   G I  +Y K+H++     
Sbjct: 62  RTSFVSSLQRDALEQNIHINVGIHEVASETRLKNLLIWIDDKGIITQKYQKIHMFDVDIK 121

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           D   ++ES  V  G +I    E    +VGL  C+DLRFPE+ LA   + AEI+  P+A+ 
Sbjct: 122 DGPVLKESASVQPGQQIPTPFETPIGRVGLSICFDLRFPEIGLALRRKDAEIITYPSAFT 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE-- 227
             P  + HW  LL ARA++T  Y++AA + G  N      G S I++P+G  +A   +  
Sbjct: 182 V-PTGKAHWEPLLRARAIETQSYVIAAAQAGPHNEKRRSYGHSIIVNPWGEVVAKLGDEH 240

Query: 228 -MPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
             P +  A++  + V ++R ++P+L      P
Sbjct: 241 QEPQIATADIDLDLVAKIRREMPLLRRNDLYP 272


>UniRef50_C1SI84 Predicted amidohydrolase n=1 Tax=Denitrovibrio acetiphilus DSM
           12809 RepID=C1SI84_9BACT
          Length = 259

 Score =  262 bits (670), Expect = 9e-69,   Method: Composition-based stats.
 Identities = 87/256 (33%), Positives = 128/256 (50%), Gaps = 3/256 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M  AA Q  ++ + E+N E     + +A+  D  L  LPE ++       +L   +  + 
Sbjct: 1   MRAAAVQINLSGIKEQNLEKSLMYIKKAS--DCDLVVLPEMVMGNRGDGVELYQLAEDVE 58

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
            G F   LR  + R  +     +   +   + +N  V     G+I A+Y KLHL+DA + 
Sbjct: 59  TGSFASSLRNAAVRYQVDVCACLWEETGTEKVYNTAVVYGSDGSIKAKYRKLHLFDALSF 118

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            ES  +  G+E  P+ E  G+K GL  CYDLRFPE   +   +GAE+ ++PAAW  G LK
Sbjct: 119 TESDYMLRGSERPPVFESGGIKCGLSICYDLRFPETYRSLVKRGAELFIVPAAWYGGELK 178

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
             H  TLL  RAL+ TCY + A  CG    G S    PF    +A      L++ EV  +
Sbjct: 179 IEHLHTLLRTRALENTCYALTANLCGGNFSGYSVSFGPFAEECSALQNDEGLLVIEVDKK 238

Query: 240 RVRQVRAQLPVLNNRR 255
            + +VR++LP L N R
Sbjct: 239 HLSEVRSKLPCLENFR 254


>UniRef50_D2A1E5 Putative uncharacterized protein GLEAN_07103 n=3 Tax=Coelomata
           RepID=D2A1E5_TRICA
          Length = 445

 Score =  261 bits (668), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 87/279 (31%), Positives = 135/279 (48%), Gaps = 22/279 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  QF  T+  E N +I   L+++AA+  A +  LPEA      +  +     A+ L G
Sbjct: 8   VAVCQFTATNNKENNLQIVKQLVSEAAQKQAKIVFLPEASDYIAANKNEAKA-FAEPLNG 66

Query: 63  EFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA---- 116
             +   R  +K   +   +   H      + +N  V +   G I + Y KLHL+D     
Sbjct: 67  TLMNEYRNLAKTRKVWLSVGGFHELVNEHQIFNTHVLIDDEGEIKSVYKKLHLFDVSIPE 126

Query: 117 --FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               ++ES   +AG  + P +      + L  CYDLRFPEL++ Q  QGA IL  P+A+ 
Sbjct: 127 LNVNLRESDLNEAGRHLVPPVMTPAGPLALAICYDLRFPELSIIQRKQGANILTYPSAFT 186

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA---- 225
           +      HW TLL +RA++T CY++AA + G  N      GQ+ I+DP G  IA      
Sbjct: 187 KAT-GALHWETLLRSRAIETQCYVIAAAQYGKHNEKRTSYGQALIVDPQGKIIAECPKYR 245

Query: 226 ---SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
                  ++ +AE+    +++VR ++PV  +RR    QL
Sbjct: 246 EGHETNQSIAIAEIDSNLIQKVRTEMPVFQHRRSDIYQL 284


>UniRef50_A1SD43 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Nocardioides sp. JS614 RepID=A1SD43_NOCSJ
          Length = 261

 Score =  261 bits (667), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 91/258 (35%), Positives = 128/258 (49%), Gaps = 8/258 (3%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +   Q A     E N      L+ +     + L   PEA               A+ L
Sbjct: 10  LRITLVQHASGLEPEAN----RRLLGELTPAGSDLVVFPEAFARDFGDAGSDVSAYAESL 65

Query: 61  EGEFLGRLRRESKRNMMTTILTIHV-PSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           +G F   + R +     T +  +      P R +N LV    G   A Y K+HLYD+F  
Sbjct: 66  DGPFATEVARVAADRGTTVVAGLFEAGEDPTRPFNTLVL--RGAAEASYRKVHLYDSFGY 123

Query: 120 QESRRVDAG-NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           +ES R+ AG    A ++EV G +VGLMTCYDLRFPELA      GA++LV+P+AWV GP 
Sbjct: 124 RESDRLTAGPTGPAVVVEVGGFRVGLMTCYDLRFPELARTLVDAGAQLLVVPSAWVAGPR 183

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K  HW TL+ ARA++ T ++ A G+ G +  G S ++DP G  +  A +  A++ A V  
Sbjct: 184 KVDHWRTLVRARAIENTVFVAAVGQPGPRYTGHSMVVDPLGDVLVEAGDEAAVVTATVDL 243

Query: 239 ERVRQVRAQLPVLNNRRF 256
           E +   R   P L NRR 
Sbjct: 244 EALAAARRTNPSLANRRL 261


>UniRef50_C4DVK2 Predicted amidohydrolase n=1 Tax=Stackebrandtia nassauensis DSM
           44728 RepID=C4DVK2_9ACTO
          Length = 272

 Score =  261 bits (667), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 89/257 (34%), Positives = 138/257 (53%), Gaps = 3/257 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +LV   Q        +N   C   + +A      L   PE + +R D  +      A+ L
Sbjct: 7   LLVGCVQMRSDLDPGENLRQCLRYLDEARTAGVDLLIFPETVSSRVDDPS--RAPQAESL 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +  F+  L + ++   +T I  +   +   R +N LVAL+ G  VARY K+HLYDA A+ 
Sbjct: 65  DDGFVAGLAKATEGLDLTVIAGV-TETHDDRPFNTLVALRDGQRVARYRKIHLYDACAMA 123

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES  +  G+       V+G +VG+MTCYD+RFPEL+   A +GA++L +P +WVRGPLKE
Sbjct: 124 ESDTIAPGDGPVSTFAVKGFEVGMMTCYDIRFPELSRLLAERGADLLAVPTSWVRGPLKE 183

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
            HW+T   ARAL+ T Y+  A + G   +G + ++ P GV ++  ++   L+ A +  + 
Sbjct: 184 EHWTTFCKARALENTVYLAGACQTGGSRVGLTSVVAPDGVIVSRLAQHEGLVTARIGRDA 243

Query: 241 VRQVRAQLPVLNNRRFA 257
           +   R   P+L  RRFA
Sbjct: 244 LTAAREAFPLLEQRRFA 260


>UniRef50_A2Q9D7 Catalytic activity: nitrilases catalyze a nitrile + H(2)O <=> a
           carboxylate + NH(3) n=2 Tax=Dikarya RepID=A2Q9D7_ASPNC
          Length = 274

 Score =  260 bits (665), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 88/266 (33%), Positives = 140/266 (52%), Gaps = 15/266 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +L A GQ   T+    N   C +L+ +AA   A    LPEA        A+    +  + 
Sbjct: 2   VLTAVGQLCSTASLAANLAQCQTLVRKAAAAGAKALFLPEASDYIASSPAETISLARSVQ 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD---- 115
           + EF+  L++E++   +   + IH P+  GR  N L+ +   GNI  RY K+HL+D    
Sbjct: 62  DSEFVLGLQKEAQLANLHINVGIHEPAANGRIKNTLIWINEQGNITQRYQKVHLFDVDIK 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               ++ES  V+ G EI P  E    +VGL  C+DLRFPE++LA   Q A+I+  P+A+ 
Sbjct: 122 GGPVLKESASVEKGMEILPPFETPVGRVGLSICFDLRFPEISLALRRQNAQIITYPSAFT 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE-- 227
             P    HW TLL ARA++T  Y++AA + G  N      G S I++P+G  +A   +  
Sbjct: 182 V-PTGTAHWETLLRARAIETQSYVIAAAQAGPHNEKRRSYGHSMIVNPWGEVVAKLGDEY 240

Query: 228 -MPALIMAEVTPERVRQVRAQLPVLN 252
             P + +A++  + + +VR ++P+L 
Sbjct: 241 QEPQIAVADIDLDLLAKVRREMPLLR 266


>UniRef50_Q23ND3 Hydrolase, carbon-nitrogen family protein n=1 Tax=Tetrahymena
           thermophila SB210 RepID=Q23ND3_TETTH
          Length = 284

 Score =  260 bits (665), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 83/276 (30%), Positives = 131/276 (47%), Gaps = 18/276 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           LV   Q   T   ++N E     + QA E  A +   PEA  A        + ++A+ ++
Sbjct: 8   LVGVVQMCSTHNKKQNMEFILQNLKQAHEKQAKICFFPEAF-AMISRSFAETFENAEYID 66

Query: 62  GEFLGRLRRESKRNMMTTILTIHVP---STPGRAWNMLVALQA-GNIVARYAKLHLYD-- 115
           GE +  LR  +K+  +   L            +  N  + +   GNIV  Y KLHL+D  
Sbjct: 67  GEMINCLRDHAKKYNLWLSLGGFQERLKENDKKMGNTHIIIDNLGNIVQTYKKLHLFDIS 126

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA-LQGAEILVLPA 171
                 I ES     G+++  +++    ++GL  CYDLRFPEL    A  Q AEIL++P+
Sbjct: 127 IDTKNTISESSGYVFGDQVPNVVDSPAGRLGLSICYDLRFPELFRLLAVQQKAEILLVPS 186

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS 226
           A+ +    + HW TLL ARA++  C+++AA + G  N      G S +IDP+G  +    
Sbjct: 187 AFFK-KTGQAHWHTLLKARAIENQCFVIAAAQAGQHNDKRESYGHSLVIDPWGEVLLDMG 245

Query: 227 EMP-ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
                +   E+  E++  VR  LP +N+ R    +L
Sbjct: 246 PEKLGIDFVEIDLEKIDTVRKGLPAINHIRNDIYKL 281


>UniRef50_UPI0001B416B7 carbon-nitrogen hydrolase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI0001B416B7
          Length = 271

 Score =  259 bits (662), Expect = 7e-68,   Method: Composition-based stats.
 Identities = 74/261 (28%), Positives = 129/261 (49%), Gaps = 2/261 (0%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A  Q    +  + +          AA N A L   PE  +    +  D  +++A++L
Sbjct: 13  VKIALTQLKPVADKDVSLRNIEYYAGTAAANSADLIVFPEYYMFYSQY-KDAIIRNAEVL 71

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
            G ++ R++  S+ N +  I  I+        ++  V +  G ++  Y K HLYDAF  +
Sbjct: 72  NGNYIKRIKEISRTNKIGIITGINEV-YDHNYYDTAVYVNDGELLNYYRKSHLYDAFGYR 130

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES     GN    + ++  +  G++ CYD+RFPE+    +L  A++++L +AW  GP+KE
Sbjct: 131 ESDIYTYGNGPFKISKIGNINFGMLICYDIRFPEVFRNYSLNDADMVILISAWFAGPIKE 190

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
             W +L++ RAL+ T Y+  +   G    G +   DP G  I  A+E   +I + +   R
Sbjct: 191 EQWLSLVSTRALENTTYLATSNMIGGGFTGITTFTDPIGAIINRAAEDEDIIYSIIDTNR 250

Query: 241 VRQVRAQLPVLNNRRFAPPQL 261
           +  VR ++PVL  RR    +L
Sbjct: 251 ISTVRKKMPVLKQRRPELYKL 271


>UniRef50_B2SXB2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=15 Tax=Proteobacteria RepID=B2SXB2_BURPP
          Length = 283

 Score =  259 bits (662), Expect = 7e-68,   Method: Composition-based stats.
 Identities = 80/266 (30%), Positives = 115/266 (43%), Gaps = 16/266 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             VAA Q   T   E+N      L+A+AA   A L  LPE        D D         
Sbjct: 19  FRVAALQMVSTPDRERNLAEAGRLIAEAAAEGAQLVLLPEYFCFMGFKDTDKLAVREPYQ 78

Query: 61  EGEFLGRLRRESKRNMMTTILT---IHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDA- 116
           +G     L   ++R+ +  I     +  P         LV    GN VARY K+HL++  
Sbjct: 79  DGPIQRFLADAARRHQVWVIGGTLPLMSPEAARVLNTTLVFDPQGNEVARYDKIHLFNFE 138

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               +  E+R +  G E     E    +VGL  CYDLRFPEL          ++V+P+A+
Sbjct: 139 KGEESFDEARTICPGGE-VRTFEAPFGRVGLSVCYDLRFPELYRRM--GDCALVVVPSAF 195

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEM 228
                   HW  LL ARA++  CY++AA + G         G S +IDP+G  +A   E 
Sbjct: 196 TY-TTGRAHWEMLLRARAVENQCYVLAAAQGGKHENGRRTWGHSMLIDPWGEIVAVRDEG 254

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNR 254
             ++   +   R+ +VR  LP   +R
Sbjct: 255 AGVVAGNLERARIDEVRQSLPAWRHR 280


>UniRef50_Q54JM9 Nitrilase homolog 2 n=1 Tax=Dictyostelium discoideum
           RepID=NIT2_DICDI
          Length = 328

 Score =  259 bits (662), Expect = 7e-68,   Method: Composition-based stats.
 Identities = 65/274 (23%), Positives = 123/274 (44%), Gaps = 17/274 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              A  Q       E+N +     + +AA+N A L +LPE       +      K ++  
Sbjct: 53  FKFAGIQLLCGDNKEENVQNAIKHIDEAAKNGAKLISLPECF--NSPYSTSTFEKYSETE 110

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP--STPGRAWNMLVAL-QAGNIVARYAKLHLYD-- 115
           +GE + +L   +KRN +  +           G+ +N        G +V ++ K+HL+D  
Sbjct: 111 DGETVKKLSEAAKRNQIFLVGGSIPEIDKATGKIYNTCFIFNDKGEVVKKHRKIHLFDID 170

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES  +  G+    ++++   K+G+  CYD+RFPELA+  +  GA+ L+ P A
Sbjct: 171 VPNKIRFKESETLTPGDS-FSVVDIGYCKIGVAICYDIRFPELAMLYSKMGAKFLIYPGA 229

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASE 227
           +        HW  L   RA+D   ++ A     N     +  G S I++ +G  +A   E
Sbjct: 230 FNM-VTGPAHWELLQRGRAVDNQVFVAAISPARNPSSTYQAWGHSTIVNSWGTILATTDE 288

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             ++I +++    + + R+ +P+ + +R    +L
Sbjct: 289 HQSIIYSDIDLNTLNETRSSIPIYSQKRDDLYKL 322


>UniRef50_Q6L0F7 Carbon-nitrogen hydrolase family n=1 Tax=Picrophilus torridus
           RepID=Q6L0F7_PICTO
          Length = 256

 Score =  259 bits (662), Expect = 7e-68,   Method: Composition-based stats.
 Identities = 72/253 (28%), Positives = 124/253 (49%), Gaps = 3/253 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A  Q   +   E N E        AA N A L   PE  +    +D     ++A+ +
Sbjct: 2   IRIALTQIHSSMDKESNLEKLRKYTEIAASNGADLIVFPEYFMF-YSNDKKYLNENAEPI 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
            G ++  + +    N ++ I+ I         ++  V + +G++   Y K  LYDAF  +
Sbjct: 61  NGIWVKNVIKIFNENSISGIVCI-NELNDNNVFDTAVYI-SGDVKGYYRKKMLYDAFGYR 118

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES    +GN    L  +  +  G++ CY++RFPEL    +  GA+++++P+ W  GP+KE
Sbjct: 119 ESDIYKSGNGPFNLYRINDISFGILICYEIRFPELFRNYSKNGADMIIIPSGWFSGPVKE 178

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
             W +LL ARAL+ T Y+ ++ +      G S + DP G+    A E   +I  +V  ER
Sbjct: 179 EQWLSLLRARALENTVYIASSNQIYGDFTGISAVADPIGIISERAGESETMIFYDVKKER 238

Query: 241 VRQVRAQLPVLNN 253
           +  VR ++P+L  
Sbjct: 239 INDVRQKMPLLEQ 251


>UniRef50_B3E274 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=10 Tax=Desulfuromonadales RepID=B3E274_GEOLS
          Length = 262

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 83/264 (31%), Positives = 125/264 (47%), Gaps = 13/264 (4%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           +  AA QF V     + N     + + + AE   +L  LPE       +     V+ AQ 
Sbjct: 7   ITAAAIQFTVNQGDLDANLAYVRTALKRVAEQGVNLAVLPEMWSTGFAYK--NLVELAQR 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
            E   +  L   S +  +  + +   P+  GR +N +  +  G +VARY KLHL+     
Sbjct: 65  TEA-VVAELCELSAQYKLVIVGSQPEPADDGRVFNTIHVVDNGQMVARYRKLHLFSLLG- 122

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E R    G+    L E    KVG++ CYDLRFPEL+   AL+GA ++ +PA W +   +
Sbjct: 123 -EDRAFKGGDSWC-LAETSIGKVGVIICYDLRFPELSRRLALEGARVICVPAQWPKP--R 178

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMAE 235
           + HW TLL ARA++   Y+V+   CG        G S +IDP G  +A A E    + A 
Sbjct: 179 QEHWRTLLRARAIENQLYIVSCNACGQIGKLDFFGMSMVIDPKGEVLADAGEAACEVTAT 238

Query: 236 VTPERVRQVRAQLPVLNNRRFAPP 259
           +  + +   RAQ+P   +RR    
Sbjct: 239 LDWQVMEAWRAQIPCFGDRRPELY 262


>UniRef50_B1I274 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Candidatus Desulforudis audaxviator MP104C
           RepID=B1I274_DESAP
          Length = 272

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 72/263 (27%), Positives = 118/263 (44%), Gaps = 14/263 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL- 59
           + +   Q  VT+  E+N      + A+AA   A +  LPE       H  +   + A+  
Sbjct: 4   IKLGICQMPVTASKEQNLSRARQMAAEAARAGARVVVLPEMFNCPYQH--EFFTRFAETC 61

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLY---- 114
            +G+    L   ++   +  I      +  GR +N   V    G ++ R  KLHL+    
Sbjct: 62  PDGDTFRMLTSTARELGVYLIGGSIPEAEDGRTYNTCFVYGPDGRMLGRQRKLHLFNIET 121

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           D    +ES  +  G     +     +  G+  C+DLRFPEL    A +GAE++V PAA+ 
Sbjct: 122 DDLVFRESDTLSPGTGPPTVFVTPLVTFGVAICFDLRFPELFRDLAARGAELIVAPAAFN 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  LL ARA+D   ++  AG    +       G S +++P+   IA A E  
Sbjct: 182 T-FTGPPHWELLLRARAVDNQVFVAGAGPAWTEDSPYPYYGHSLVVNPWAEVIACAGERE 240

Query: 230 ALIMAEVTPERVRQVRAQLPVLN 252
            +++AE+   +V +VR +LP+  
Sbjct: 241 TVLLAEIDLGQVAEVRKKLPLHR 263


>UniRef50_A0L7H1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L7H1_MAGSM
          Length = 275

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 75/267 (28%), Positives = 122/267 (45%), Gaps = 15/267 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +L A  Q    +    N      L+ +AA   A L  LPE        + +         
Sbjct: 7   VLAAVIQTNSGNDRVHNLMRAEQLLEEAATAGAKLLVLPENFSFFGADEKEKLAHQEDPQ 66

Query: 61  EGEFLGRLRRESKRNMMTTILTIH---VPSTPGRAWNMLVALQAGNIVARYAKLHLYD-- 115
            G  L  ++  ++R+    +       V  +   A +  V    G +VARY K+HL+D  
Sbjct: 67  HGPSLRMVQAFAQRHGAWVVAGSIPTDVGESQRVANSSFVVNDQGQVVARYDKIHLFDVT 126

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES  + AG++   +++    ++GL  CYDLRFPEL  A    GAEI  +PAA
Sbjct: 127 LNGGEGYRESDMIRAGSQPV-VVDSPFGRIGLSICYDLRFPELYRALTDAGAEIFTVPAA 185

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++  C+++A  + G         G S I++P+G  +A  ++
Sbjct: 186 FTL-TTGQVHWELLLRARAVENFCHLLAPNQWGRHPGNRKTYGSSMIVEPWGSVVARVAD 244

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNR 254
                +A + P RV + R+Q+P L +R
Sbjct: 245 GEGYALAPLDPARVARCRSQIPCLQHR 271


>UniRef50_Q0AX54 N-carbamoyl-D-amino acid amidohydrolase n=3 Tax=cellular organisms
           RepID=Q0AX54_SYNWW
          Length = 283

 Score =  258 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 79/271 (29%), Positives = 131/271 (48%), Gaps = 16/271 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           ++  Q    +  ++N +    ++A AA   A +  LPE       + A+L  + A+   G
Sbjct: 7   LSICQMKTGNDKDENLKKAGEMIAAAAGEGAEMVVLPEVF--NSPYQAELFPRYAEPFPG 64

Query: 63  EFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYDA---- 116
                L   + ++ +  +   I    + G+ +N   V  + G ++ R+ K HL+D     
Sbjct: 65  PSTDFLAAAACKHGLCIVGGSIIERDSQGKIYNSSFVFDERGELIGRHRKAHLFDIDIPG 124

Query: 117 -FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
             + +ES  ++AG  I  ++  +     LM CYD RFPELA A AL+GAE+LV+PAA+  
Sbjct: 125 RISFRESDTLNAGENIT-IVHYKSRLFALMICYDCRFPELARAAALEGAELLVIPAAFNT 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASEMPA 230
                 HW  L+  RA+D   ++VAA    N     +  G S ++DP+G  +  A     
Sbjct: 184 -TTGPAHWKLLMRCRAVDNQLFVVAASPARNPSASYQAWGHSLVVDPWGDILQEAGSGEE 242

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +I A +   R+ QVR +LP+L  RR    +L
Sbjct: 243 IIHARLDFSRLEQVRQELPLLRQRRKDLYRL 273


>UniRef50_A5GT50 Possible nitrilase n=5 Tax=Bacteria RepID=A5GT50_SYNR3
          Length = 272

 Score =  258 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 82/271 (30%), Positives = 131/271 (48%), Gaps = 16/271 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            L AA Q   T   + N      L+  AA   A L  LPE        +    ++ A  L
Sbjct: 4   FLAAALQCTSTPDPDSNFAQIEELIDLAARRGAELVGLPENFAFLGAENK--RLELAPTL 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNML-VALQAGNIVARYAKLHLYD--- 115
                  L   ++R  +  +     VP+     +N   +  + G ++A Y K+HL+D   
Sbjct: 62  AERCSRFLVTMARRYQVAILGGGFPVPAGEAATFNRSELVSRDGQVLATYDKIHLFDVDL 121

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEG-MKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  ES  + AG+ + P+ ++ G  +VGL  CYD+RFPEL    A  GAE+L++PAA
Sbjct: 122 PDGNTYTESDTITAGSSLPPVADLPGLCRVGLSICYDVRFPELYRHLAGAGAELLMVPAA 181

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +     K+ HW  LL ARA++ T Y++A  + G         G + +IDP+G  +A A  
Sbjct: 182 FTAYTGKD-HWQVLLQARAIENTSYVLAPAQTGLHYGRRQSHGHALVIDPWGTVLADAGV 240

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
            P + +A +  + ++++RAQ+P L +RR A 
Sbjct: 241 GPGVAIAPIDTDHLQRIRAQMPSLRHRRPAL 271


>UniRef50_Q0HEI5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=21 Tax=Shewanella RepID=Q0HEI5_SHESM
          Length = 282

 Score =  257 bits (658), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 76/282 (26%), Positives = 123/282 (43%), Gaps = 23/282 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAEND-------ASLFALPEALLARDDHDADLS 53
           M ++  Q   +     N     S + +              L  LPE  L    H++   
Sbjct: 1   MRISLLQCQSSRDVSANLLFIESQLEELTRQRLQWDKDAPHLVVLPECSLLFGGHESQQL 60

Query: 54  VKSAQLLEGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQA-GNIVARYAKL 111
             +           L   + R  +  +   I   +  GR ++        G+ + +Y KL
Sbjct: 61  AYAGDSHLSPLKSALSALAARYCVYMVAGTIPALAEDGRVYSRCYLFDDKGDTLGQYDKL 120

Query: 112 HLYDAFA------IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
           HL+D          +ES     GN I+ +++    K+GL  CYDLRFP+L  A  L GAE
Sbjct: 121 HLFDVDVADGTKQYRESETFCPGNHIS-VIDTPFGKIGLTICYDLRFPDLFRALRLAGAE 179

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG------NKNIGQSRIIDPFG 219
           I+ +P+A+ +    E HW  LL ARA++T C+++AA + G       +  GQS +I P+G
Sbjct: 180 IITVPSAFTK-VTGEAHWQVLLQARAIETQCFILAAAQWGAHNEGSRETWGQSMVIGPWG 238

Query: 220 VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             IA        + A++    V  +R+++PV  + RF  P L
Sbjct: 239 EVIAEQKTGTGWVHADIDVAEVHSIRSKMPVAQHNRFTAPNL 280


>UniRef50_Q94JV5 AT4g08790/T32A17_100 n=10 Tax=Viridiplantae RepID=Q94JV5_ARATH
          Length = 307

 Score =  257 bits (658), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 75/269 (27%), Positives = 126/269 (46%), Gaps = 18/269 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q    +    N   C+ L+ +AA   A L   PE      D + + SVK A+ L
Sbjct: 37  VRVAAAQMTSVNDLMTNFATCSRLVQEAALAGAKLICFPENFSFVGDKEGE-SVKIAEPL 95

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
           +G  + R    ++ + +   L             N  V +   G I   Y K+HL+D   
Sbjct: 96  DGPVMERYCSLARDSNIWLSLGGFQERFDDTHLCNTHVVIDDAGMIRDTYQKMHLFDVDV 155

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA-LQGAEILVLPAA 172
               + +ES     G +I  + +    ++GL  CYDLRFP++       Q A++L++P+A
Sbjct: 156 PGGSSYKESSFTVPGTKIVSV-DSPVGRLGLTVCYDLRFPKIYQQLRFEQKAQVLLVPSA 214

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW  LL ARA++T CY++AA + G  N      G + IIDP+G  +    +
Sbjct: 215 FTK-VTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDTLIIDPWGTVVGRLPD 273

Query: 228 M--PALIMAEVTPERVRQVRAQLPVLNNR 254
                +++A++    +  VR ++P+   R
Sbjct: 274 RVSTGIVVADIDFSLIDSVRTKMPIDKQR 302


>UniRef50_B5JWE9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=gamma proteobacterium HTCC5015
           RepID=B5JWE9_9GAMM
          Length = 282

 Score =  257 bits (657), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 82/270 (30%), Positives = 118/270 (43%), Gaps = 16/270 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L+A  Q   T   E N      L+A AAE  A +  LPE      D        +    +
Sbjct: 11  LIACVQMTTTDSVEHNLATAQRLVANAAERGAQIVVLPETFAFMGDEITQQFGVAEAFGD 70

Query: 62  GEFLGRLRRESKRNMMTTILTI----HVPSTPGRAWNMLVALQAGNIVARYAKLHLYD-- 115
           G     +   +K N +  +       H           LV   +G   ARY K+HL+D  
Sbjct: 71  GPIQTAVADWAKSNHVWIVAGTIPLRHESDRERVRAACLVFDDSGQCQARYDKVHLFDVE 130

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                + +ES     G+EIA +L+    ++G+  CYDLRFPEL  AQ   G E  VLP+A
Sbjct: 131 LPTGESYKESSVFLPGDEIA-VLDTPLGRMGVAVCYDLRFPELFRAQLDMGMEFCVLPSA 189

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++  CY  AA + G         G S I+DP+G  +   +E
Sbjct: 190 FTEAT-GQAHWLPLLQARAVENLCYFAAAAQVGEHGSGRRTHGHSVILDPWGQVVDQLAE 248

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
              +++  +  E  R  RA  P L +RR +
Sbjct: 249 GEGVVVGSIDMEHQRLTRANFPALQHRRLS 278


>UniRef50_Q7QKM8 AGAP012662-PA (Fragment) n=14 Tax=Neoptera RepID=Q7QKM8_ANOGA
          Length = 308

 Score =  256 bits (655), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 78/273 (28%), Positives = 127/273 (46%), Gaps = 15/273 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  V    EKN +    L+  A  E DA++  LPE   A    D  L+V + ++
Sbjct: 34  IKIALIQLRVVDSKEKNLKNAIDLIRIAKKEKDANVVVLPECFNAPYTADTLLNV-AEEI 92

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYDA-- 116
             GE    L   ++   +  +    V S  GR +N   V    G++VA Y K+HL D+  
Sbjct: 93  PTGETCRALSNAARDFGVHVVGGSIVESCSGRLYNTCTVWGPEGDLVATYRKVHLCDSSL 152

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                + E++   AG++ A    V   ++GL  C+D+RF E A A    G ++L+ PA  
Sbjct: 153 SGKMTVAETKLFTAGSKYAT-FTVGETRIGLGICWDMRFAEFATAYRTMGCDLLIYPAVC 211

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
              P  E HW  L  ARALD   ++       + +      G S ++DP+G  I  A+E 
Sbjct: 212 DV-PTGEQHWELLAKARALDNQAFVAFCSPARDTHAKLIPYGHSLVVDPWGRIIQRATEF 270

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             +++A++  + +  VR ++PV   +R     L
Sbjct: 271 QEIVVADLVLKELTDVRKRIPVFEQKRTDLYDL 303


>UniRef50_Q2BKP4 Putative carbon-nitrogen hydrolase n=1 Tax=Neptuniibacter
           caesariensis RepID=Q2BKP4_9GAMM
          Length = 276

 Score =  256 bits (655), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 77/272 (28%), Positives = 121/272 (44%), Gaps = 22/272 (8%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VAA Q         N      L+ QA  ++A L  LPE   A  D  A + +   +   
Sbjct: 3   RVAAVQMCSGQDLNANLAQLDGLIEQAVASNAELLLLPENF-ALLDSQALIELAFEESRS 61

Query: 62  GEFLGRLRRESKRNMMTTILTIHV------PSTPGRAWNMLVALQA-GNIVARYAKLHLY 114
              L RL++ +    +  I            +   + ++  + +   G + A Y K+HL+
Sbjct: 62  PSVLNRLKQIAHEKGIWLIAGSFPWLCDSPQNGKTKVFSRSLLIDPQGELKAHYDKVHLF 121

Query: 115 DAF------AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
           D        A +ES     G E+  + +      GL  CYDLRFPE     A  GA I++
Sbjct: 122 DVDVEDKHAAYRESDYFTPGKELV-VEQTSVGCFGLSICYDLRFPEHYQRLADMGANIML 180

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIA 223
           +P+A+     K  HW  LL ARA++T  Y++AA + G         G S I+DP+G  +A
Sbjct: 181 VPSAFTAVTGK-AHWEVLLRARAIETQSYVIAANQAGKHTASRSSWGHSMIVDPWGKVLA 239

Query: 224 AA-SEMPALIMAEVTPERVRQVRAQLPVLNNR 254
              ++ P L +A++  + VR  R  +PV  +R
Sbjct: 240 ECHNDGPGLAVADIDLQEVRNRRKAMPVTLHR 271


>UniRef50_D1Y5M0 Hydrolase C26A3.11 n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y5M0_9BACT
          Length = 283

 Score =  255 bits (653), Expect = 8e-67,   Method: Composition-based stats.
 Identities = 57/272 (20%), Positives = 114/272 (41%), Gaps = 16/272 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q  V +  + N +   + +AQ+ +  A +  LPE       +        A+  
Sbjct: 11  MKIALIQLRVDNSKQNNLDRACAFIAQSKQGGADMAILPEMFSC--PYQTKNFPLYAEKA 68

Query: 61  EGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD--- 115
            G+   +    +++N +  +   +      G+ +N   V  + G  +A + K H++D   
Sbjct: 69  GGKAWLQFSETARKNNIYLVAGSMPEVDEEGKVYNTSFVFDREGAQLASHRKAHMFDIDV 128

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES  +  G++     E E   +GL+ CYD RFPE++   A +GA+++ +PAA+
Sbjct: 129 PGGQRFRESDTLTPGDK-VTTFETEFGLMGLLVCYDFRFPEMSRIMANRGAKVIFVPAAF 187

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW  L   RA D   + V      ++         S ++ P+G      +  
Sbjct: 188 NM-TTGPAHWDLLFRCRAQDFQVFTVGCAPARDEGGCYVSYANSMVVGPWGDVKLRMATE 246

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            ++   ++    +++VR   P+ N+ R    +
Sbjct: 247 ESMEFCDIDLNELKKVRTSFPLWNHYRKGLYE 278


>UniRef50_A3ZLM3 Putative nitrilase n=1 Tax=Blastopirellula marina DSM 3645
           RepID=A3ZLM3_9PLAN
          Length = 258

 Score =  255 bits (653), Expect = 8e-67,   Method: Composition-based stats.
 Identities = 76/262 (29%), Positives = 122/262 (46%), Gaps = 17/262 (6%)

Query: 8   FAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGR 67
                  E N +    L+AQAAE  A L  LPE          +  V+ A+ + G    R
Sbjct: 1   MNAGEDKELNLQTAERLIAQAAERGAQLVVLPELFNYLG--RLENLVEHAETISGPTAVR 58

Query: 68  LRRESKRNMMTTILTIHVP--STPGRAWNMLVALQA-GNIVARYAKLHLYD----AFAIQ 120
           +R+ + ++ +  +         T  R +N  +     G  +  Y K+HL+D       + 
Sbjct: 59  MRKAALKHQIYLVAGSFAERSETESRVFNTSLIFDPLGKQIGVYRKIHLFDIDLPDVQVH 118

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES  V  G+E   L +     V    CYDLRFPE+  +  L+    L LPAA+       
Sbjct: 119 ESSFVAPGSE-VSLCQTALGGVAQAICYDLRFPEIVRSYDLEKVACLALPAAFTA-KTGA 176

Query: 181 HHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAA-SEMPALIMA 234
            HW  L+ +RA++   +++AA + G      ++ G S I+DP+G  +A A  +   +I A
Sbjct: 177 AHWQILVRSRAIENQLFLIAANQYGRYTNGIQSYGHSLIVDPWGTILAEAGGDAEEVITA 236

Query: 235 EVTPERVRQVRAQLPVLNNRRF 256
           E++ ER+R+VR  +P L +RR 
Sbjct: 237 EISLERLREVRQHMPALRHRRM 258


>UniRef50_D1BX77 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Actinomycetales RepID=D1BX77_XYLCX
          Length = 298

 Score =  255 bits (651), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 95/260 (36%), Positives = 137/260 (52%), Gaps = 6/260 (2%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q  V +    N +   +++  AA   A L  LPE   A       +  + A+ L
Sbjct: 32  VRVAIAQIEVGADHAANRDAVTAVVRDAAARGADLVVLPEY--ASGFEPRGVGPEHAEPL 89

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
           +G F+  LR  ++ + +  +    +P   PGRA N +VA+ A G +   Y K+HLYDAF 
Sbjct: 90  DGPFVSLLRALAREHGLAIVAGTTLPGEAPGRASNAIVAVGAQGELAGAYRKVHLYDAFG 149

Query: 119 IQESRRVDAG--NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
            +ES R++ G  +       V G+ VG++TCYDLRFPE A      GA+ ++ PAAWV G
Sbjct: 150 TRESDRLEPGPADAAPLTFAVGGLTVGVLTCYDLRFPEAARRVVDAGAQAILYPAAWVAG 209

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
           PLK  HW TLL ARA++ T  +V  G  G    G+S ++D  GV +    E P L +A +
Sbjct: 210 PLKADHWRTLLRARAIENTVAVVGVGMAGRTVTGRSLVVDADGVVVLELDETPQLAVATL 269

Query: 237 TPERVRQVRAQLPVLNNRRF 256
            P    + RA  P L NRR+
Sbjct: 270 DPTATARTRAANPSLANRRY 289


>UniRef50_Q9LE50 Nitrilase 1 like protein n=2 Tax=Viridiplantae RepID=Q9LE50_ARATH
          Length = 316

 Score =  255 bits (651), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 74/265 (27%), Positives = 125/265 (47%), Gaps = 18/265 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q    +    N   C+ L+ +AA   A L   PE      D + + SVK A+ L
Sbjct: 37  VRVAAAQMTSVNDLMTNFATCSRLVQEAALAGAKLICFPENFSFVGDKEGE-SVKIAEPL 95

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
           +G  + R    ++ + +   L             N  V +   G I   Y K+HL+D   
Sbjct: 96  DGPVMERYCSLARDSNIWLSLGGFQERFDDTHLCNTHVVIDDAGMIRDTYQKMHLFDVDV 155

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA-LQGAEILVLPAA 172
               + +ES     G +I  + +    ++GL  CYDLRFP++       Q A++L++P+A
Sbjct: 156 PGGSSYKESSFTVPGTKIVSV-DSPVGRLGLTVCYDLRFPKIYQQLRFEQKAQVLLVPSA 214

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW  LL ARA++T CY++AA + G  N      G + IIDP+G  +    +
Sbjct: 215 FTK-VTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDTLIIDPWGTVVGRLPD 273

Query: 228 M--PALIMAEVTPERVRQVRAQLPV 250
                +++A++    +  VR ++P+
Sbjct: 274 RVSTGIVVADIDFSLIDSVRTKMPI 298


>UniRef50_A2FF61 Hydrolase NIT3, putative n=4 Tax=cellular organisms
           RepID=A2FF61_TRIVA
          Length = 273

 Score =  254 bits (649), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 115/272 (42%), Gaps = 15/272 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +   Q +       N    A  + + A++ A +  LPE       +      + ++  
Sbjct: 2   VKIGIVQLSSGDDKAANVARAAEKVKKCAQDGAEIVVLPEIF--NGPYSTAKFREYSEPE 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD---- 115
            GE   RL   +K N +  I          + +N        G  + ++ K+H++D    
Sbjct: 60  GGETWQRLSNMAKENNIILIGGSISEFCEDKIYNTSYIFDQQGKQIGKHRKMHMFDIDVK 119

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ES  +  GN+   +++    K+G+  C+D RFPELA   AL+GA+++++P A+ 
Sbjct: 120 GGQRFKESDALTPGNQ-VTVVDTSICKIGVCICFDFRFPELARLMALKGAKMIIVPGAFN 178

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  L   RA+D   + +      N      +   S ++ P+G  I  A    
Sbjct: 179 M-TTGPAHWELLFRQRAVDNQVFTIGCAPARNTEASYVSFANSIVVGPWGDVIYNAGIEE 237

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
              + E+  E+V  +R QLP+L+ RR    ++
Sbjct: 238 KAEVVEIDLEKVDSIRQQLPLLSARRTDVYEM 269


>UniRef50_B0TEY4 Hydrolase, carbon-nitrogen family n=1 Tax=Heliobacterium
           modesticaldum Ice1 RepID=B0TEY4_HELMI
          Length = 265

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 83/269 (30%), Positives = 113/269 (42%), Gaps = 17/269 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M V   QF V +   + N E  A  MA+A E    +  LPE          D    +A  
Sbjct: 1   MKVGLLQFNVCSGDRKANVETVARYMAEAREACPDVLVLPEMWTTGY----DWVNLAALA 56

Query: 60  LEGEFLGRLRR-ESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF 117
            +GE  G L    +K    T +         GR  N L A    G  +  Y K+HL+   
Sbjct: 57  DDGESFGALLACWAKETGATIVGGSSPVGANGRYANTLYAYTPEGERILSYEKVHLFGMM 116

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E R + AG+       +  +  G + CYDLRFPE      L G EIL +PA W    
Sbjct: 117 G--EERHLAAGSSTGNFC-IGAVPCGAVICYDLRFPEWIRKTVLAGCEILFIPAQWPLSR 173

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPALI 232
           L   HW  LL ARA++  CY++A    G         G S +IDP+GV    A E    I
Sbjct: 174 L--DHWRILLQARAIENQCYVIACNRTGRDEQGVAFAGHSMVIDPWGVIAVEAGEEEGWI 231

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             E+  ++V +VR ++ V  +RR      
Sbjct: 232 WGEIDRDKVERVRRKMTVFADRRLDLYDF 260


>UniRef50_A8I529 Carbon-nitrogen hydrolase family protein n=8 Tax=Proteobacteria
           RepID=A8I529_AZOC5
          Length = 282

 Score =  253 bits (647), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 78/270 (28%), Positives = 115/270 (42%), Gaps = 15/270 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQA-AENDASLFALPEALLARDDHDADLSVKSAQL 59
           + V+  Q         N    ASL+  A A +   L  LPE      D  A     +   
Sbjct: 15  VKVSLVQMNTQGDKAANLATAASLIEAAVAADKPDLVVLPEYYAFLGDTPAQAQDAAETF 74

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
            +GE    ++  +K+  +               +N  V     G  +ARY K+HL+D   
Sbjct: 75  PDGESYQLMKGLAKKLKVAIHAGSVAEREGNSFYNTTVVFGPDGEELARYRKIHLFDVEI 134

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES  V  G ++    E+ G  VG   CYD+RFPEL      +GA+I+VLPAA+
Sbjct: 135 TGGTVYRESDTVSRGEDVVT-YELGGKTVGCAICYDIRFPELFRKLRDKGADIIVLPAAF 193

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK------NIGQSRIIDPFGVTIAAASE 227
                K+ HW  L  ARA++T  + +A G+ G          G S +IDP+G   A AS+
Sbjct: 194 TLMTGKD-HWEILARARAIETQTWFLAVGQTGPHAGGKKWCWGHSMVIDPWGHITAQASD 252

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
                   +      +VRA +PV N+   A
Sbjct: 253 GVGFTTGRLEFGYTEKVRANVPVANHHVLA 282


>UniRef50_A5V962 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Sphingomonas wittichii RW1 RepID=A5V962_SPHWW
          Length = 268

 Score =  253 bits (646), Expect = 5e-66,   Method: Composition-based stats.
 Identities = 84/266 (31%), Positives = 129/266 (48%), Gaps = 15/266 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +   Q  V    E N       + + A +   +  LPE  +A     A L   +    
Sbjct: 1   MKIGVVQINVGMDKEANIARLDRQVRRLAADGCDIVFLPEMAMALTGKPAALQAAAE-AE 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLH-----LY 114
           +G ++  ++  +K   +   L   +     R  N  LV  + G  + RY+KLH     L 
Sbjct: 60  DGAYVTAMKALAKECGINLHLGSFMERRGDRFLNTSLVFDRQGECIGRYSKLHRFDIDLP 119

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           D  AI+ES  VD G+ I  ++++EG+KV L  CYDLRFPEL  A    GA+++ +PAA+ 
Sbjct: 120 DGTAIRESDVVDRGDAIT-VVDIEGLKVALTICYDLRFPELFRALVDLGADLITVPAAFT 178

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECG------NKNIGQSRIIDPFGVTIAAASEM 228
                  HW  LL ARA++T CY+ A G+ G        N G S IIDP+G  +  AS  
Sbjct: 179 FQT-GADHWEVLLRARAIETECYIAAPGQVGGFDDGKYLNFGHSMIIDPWGTVVGQASNG 237

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNR 254
             +  A +  + ++ VRA++P+  +R
Sbjct: 238 EGVASAVIDRDYIQTVRARIPLRKHR 263


>UniRef50_D1Y828 Hydrolase n=1 Tax=Pyramidobacter piscolens W5455 RepID=D1Y828_9BACT
          Length = 275

 Score =  252 bits (645), Expect = 8e-66,   Method: Composition-based stats.
 Identities = 81/271 (29%), Positives = 132/271 (48%), Gaps = 16/271 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            L++  Q    +  + N +     + +AA + A   A+ E +        D    SA+ +
Sbjct: 4   FLMSVLQIDSQADKKANLDKIGRFIDEAASHGARFVAMAENV--HYCGPKDGVFASAETI 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYD-- 115
            G        ++K+  +           PG  R +N  +     G++ ARY K+H+YD  
Sbjct: 62  PGPMSAFFAAKAKQYKIWLHCGSIGEVIPGESRLYNTTLLYNPRGDLAARYEKIHMYDVE 121

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                + +ES     G+ I  + + E  KVGL  CYD+RFPE+    ALQGA+++ +PA 
Sbjct: 122 IENGPSTRESDTKKPGHRIV-VADTEFCKVGLSICYDMRFPEMYRIMALQGAKVMFVPAN 180

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEM 228
           +      + HW  +L  RA++  CY+VA  + G     +  G+S II+P+GVT+A A + 
Sbjct: 181 YTL-FTGKDHWECILKTRAIENQCYVVAPAQIGKKPAFQAYGRSMIINPWGVTVACAEDR 239

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             +I AE+ P+ V Q+R QLP L NR+    
Sbjct: 240 ETIIYAEIDPDYVNQIREQLPSLKNRQPGAY 270


>UniRef50_A6F4Z1 Predicted amidohydrolase n=2 Tax=Marinobacter RepID=A6F4Z1_9ALTE
          Length = 286

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 71/274 (25%), Positives = 121/274 (44%), Gaps = 21/274 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VAA Q   T     N    A L+ +AA+  AS+  LPE              +     +
Sbjct: 15  RVAAIQMVSTHDIAANLNEAARLLKEAADAGASIAVLPENFAVLATKQMIGCGRREAEPD 74

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTP-------GRAWNMLVALQA-GNIVARYAKLHL 113
                 L +++    +  +      +          R           G  VARY K+HL
Sbjct: 75  NVIRQFLAQQATELGIWVVGGSLPIAARPDWSAVTDRVRACCYVYDDRGREVARYDKIHL 134

Query: 114 YDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +DA         +ES   + G ++  +++    ++G+  CYDLRFPEL      Q AE +
Sbjct: 135 FDATVEDAQGQYRESDTFEPGEDVV-VIDTPAGRLGMAICYDLRFPELFRQLREQDAEWV 193

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTI 222
            LP+A+      + HW  L+ ARA++   ++VAA + G      +  G S I+DP+G  +
Sbjct: 194 SLPSAFTW-YTGDAHWHALIRARAIENQVWLVAAAQGGQNSERRRTYGHSAIVDPWGRIL 252

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           +   E P ++++E+  E ++ +R ++PV  +RR 
Sbjct: 253 SEIDEGPGIVVSELDRETLKDIRTRMPVWEHRRL 286


>UniRef50_Q6C005 YALI0F29139p n=1 Tax=Yarrowia lipolytica RepID=Q6C005_YARLI
          Length = 289

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 92/284 (32%), Positives = 138/284 (48%), Gaps = 24/284 (8%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L A GQF  T+    NA I A L+ +AA   A    LPEA         +    +     
Sbjct: 3   LAAVGQFCATNSLTHNASIVAGLVHRAAALGAQALFLPEASDYISGSPKEGLSLARNAEN 62

Query: 62  GEFLGRLRRESKR------NMMTTILTIHV-PSTPGRAWNMLVALQ-AGNIVARYAKLHL 113
              +  +R   K       + +   + +H   S+  R  N L+ L   G+IV RY K+HL
Sbjct: 63  SPMIAAIREAQKEIKQSGMSGIEVSVGVHELSSSSDRVRNTLLWLDSNGDIVNRYQKVHL 122

Query: 114 YDAFA-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
           +D        +QES+ V+ G+E+    E     VG   CYD+RFPELAL    QGA+IL 
Sbjct: 123 FDVEVPNGPILQESKSVEPGSELPKPFETPVGTVGPAICYDIRFPELALLLRKQGAQILQ 182

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-------NKNIGQSRIIDPFGVT 221
            P+A+        HW  L  ARA+DT CY++     G        ++ G + IIDP+G  
Sbjct: 183 FPSAFTV-RTGAAHWHVLARARAIDTQCYVMMPALVGKHTEDGKRESYGHAMIIDPWGTV 241

Query: 222 IAAASEMP---ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           +A AS++    A+I+A++  E++++VR  +P+ + RR     LL
Sbjct: 242 LAEASDIDSSAAVIVADINLEQLKKVRTNMPLWDQRRNDVYSLL 285


>UniRef50_Q0F1V1 Hydrolase, carbon-nitrogen family protein n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0F1V1_9PROT
          Length = 272

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 79/268 (29%), Positives = 121/268 (45%), Gaps = 13/268 (4%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M VA  Q    +  E N E  + L+ QAA   A L  LPE         +D  + +    
Sbjct: 6   MRVACIQMNSGADREANLEQASLLLQQAASAGAELAVLPENFSLMGASLSDKRLLAEPQE 65

Query: 61  EGEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNML-VALQAGNIVARYAKLHLY---- 114
               L  L  ++  + M  +     +     +  N   V    G + A Y K+HL+    
Sbjct: 66  NSTVLAFLSEQAITHRMAIVGGSTLLTGGQDKLRNACPVFSADGRMRAIYDKIHLFDVDL 125

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           D  +  ES  V AG     +  +   + GL  CYD+RFPEL    A  G +++ + AA+ 
Sbjct: 126 DGESYHESESVVAGEHPCSVA-LGDFRFGLSICYDIRFPELYRHYADSGCDVVCVVAAFT 184

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAASEMP 229
                  HW TLL ARA++  CY++A+ +      G +  G S IIDP+G  +A   E  
Sbjct: 185 EQTGH-AHWQTLLRARAIENQCYLLASAQWGVHADGRRTWGHSMIIDPWGEVMALQEEST 243

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFA 257
            +IMA++T  R+  +R  LP L +R+ +
Sbjct: 244 GVIMADLTSARLAHIRKILPSLQHRQIS 271


>UniRef50_B2SLI2 Beta-alanine synthetase n=122 Tax=Bacteria RepID=B2SLI2_XANOP
          Length = 299

 Score =  252 bits (643), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 64/278 (23%), Positives = 110/278 (39%), Gaps = 21/278 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARD--DHDADLSVKSAQLL 60
           VA  Q       E N  + AS +A+AA   A L  L E         H++      A+ +
Sbjct: 13  VALIQERNHGDAEANLAVIASRVAEAAAQGAKLVLLQELHNGAYFCQHESVDEFDLAEPI 72

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
            G    RL   +K++ +  + ++      G   N  V  +  G ++ +Y K+H+ D    
Sbjct: 73  PGPSTERLGALAKQHGVVLVASLFERRAAGLYHNTAVVFEKDGRLLDKYRKMHIPDDPGF 132

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E      G+     ++    ++G++ C+D  +PE A   AL GAE+L+ P A    P  
Sbjct: 133 YEKFYFTPGDLGFTPIDTSVGRLGVLVCWDQWYPEAARLMALAGAELLLYPTAIGWDPDD 192

Query: 180 --------EHHWSTLLAARALDTTCYMVAAGECGNK----------NIGQSRIIDPFGVT 221
                      W       A+     +++    G++            G S ++ P G  
Sbjct: 193 QQPEQERQRDAWVLSHRGHAVANGVPVLSCNRVGHEPSPLGASGIQFWGNSHVLGPQGEF 252

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           IA A + P +++ +V  +R   VR   P L +RR    
Sbjct: 253 IAEAGQDPTVLICDVDLQRSEHVRRIWPFLRDRRIDAY 290


>UniRef50_D1A7Y1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Streptosporangineae RepID=D1A7Y1_THECD
          Length = 261

 Score =  251 bits (642), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 96/267 (35%), Positives = 146/267 (54%), Gaps = 16/267 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q  V     +N E     +A+A    A L   PEA+  R  +D       A+ LE 
Sbjct: 1   MALCQIPVGDDPAENLEQVRRALARA--EGADLAVFPEAVPVRFGND---LTAVAEPLEQ 55

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQE 121
            F G LR+ ++ +    I  +  P+  GR +N  VA+  +G  V  Y K+HL+DAF  +E
Sbjct: 56  GFAGELRKLAREHGTALIAGVFEPAGDGRVYNTAVAIDASGRPVGAYRKIHLFDAFGDRE 115

Query: 122 SRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEH 181
           S RV  G+    ++E+ G ++GL+TCYD+RFPELA A   +GA++LV+ AAW +G  KE 
Sbjct: 116 SARVAPGD-APVVVELAGARIGLITCYDVRFPELARALVDRGAQVLVIIAAWAQGVFKEE 174

Query: 182 HWSTLLAARALDTTCYMVAAGECGNKN---------IGQSRIIDPFGVTIAAASEMPALI 232
           HW+TL+ ARA++ T ++VA  +  ++          +G+S +IDP G  +A     PA+ 
Sbjct: 175 HWTTLVRARAIENTTWVVAVDKAPDRTRPPEGGPGGVGRSMLIDPMGTVVADLGPFPAVR 234

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +AE+  E   +VR  LP L +RR    
Sbjct: 235 VAEIDQEVTERVRRILPSLQHRRPDAY 261


>UniRef50_C7R9G8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7R9G8_KANKD
          Length = 273

 Score =  251 bits (641), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 62/269 (23%), Positives = 114/269 (42%), Gaps = 15/269 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q   +S  + N      L+  AA   A    LPE+    + ++        +  
Sbjct: 5   VKVALIQMTSSSEVDDNLAKAEKLIESAAAQGAQFIVLPESFALMEKYNGQKLEHVERDG 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIH--VPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD-- 115
           +G+    +   +K+  +  +            + +       + G+++A Y K+HL+D  
Sbjct: 65  QGKVQDWMSSLAKKLKLVLVGGTIAVESEIENKPYARCYVYQEDGSLLAHYDKIHLFDVS 124

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                +  ES    AG+E       +G+  G   CYDLRFPEL         ++++ P+A
Sbjct: 125 VKEGESYSESSNTLAGSEPVT-FNWQGITFGCSVCYDLRFPELYRYYQTHNVDVILAPSA 183

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +     K  HW  LL ARA++   ++VA  + G  +      G S +IDP+G  I    E
Sbjct: 184 FTLATGKV-HWKLLLQARAVENLAFVVAPNQTGTHDNQRKTFGHSMVIDPWGEVIDELQE 242

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
              + +A +   ++  ++ + PV  +R+ 
Sbjct: 243 DEGISIATLNINKIDMIKEKFPVHLHRKL 271


>UniRef50_D2UDH5 Putative carbon-nitrogen hydrolase family protein n=1
           Tax=Xanthomonas albilineans RepID=D2UDH5_XANAL
          Length = 348

 Score =  251 bits (641), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 65/278 (23%), Positives = 108/278 (38%), Gaps = 21/278 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARD--DHDADLSVKSAQLL 60
           VA  Q         N     S +A+AA   A L  L E         H++  +   A+ +
Sbjct: 62  VALIQERNHGDAAANLSAIESRVAEAAAQGARLVLLQELHNGAYFCQHESVEAFDLAEPI 121

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
            G    RL   +KR+ +  + ++      G   N  V  +  GN++ +Y K+H+ D    
Sbjct: 122 PGPSSQRLSALAKRHGVVLVGSLFERRAAGLYHNTAVVFEKDGNLLGKYRKMHIPDDPGF 181

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E      G+     ++    ++G++ C+D  +PE A   AL GAE+L+ P A    P  
Sbjct: 182 YEKFYFTPGDLGFTPIQTSVGRLGVLVCWDQWYPEAARLMALAGAELLLYPTAIGWDPDD 241

Query: 180 --------EHHWSTLLAARALDTTCYMVAAGECGNK----------NIGQSRIIDPFGVT 221
                      W       A+     +++    G++            G S ++ P G  
Sbjct: 242 AQAEQERQRDAWVLSHRGHAVANGIPVLSCNRVGHEPSPLGASGIQFWGNSHVLGPQGEF 301

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           IA A   P +++ EV  +R   VR   P L +RR    
Sbjct: 302 IAEAGTDPTVLVCEVDLQRSEHVRRIWPFLRDRRIDAY 339


>UniRef50_C8WPR2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WPR2_EGGLE
          Length = 280

 Score =  251 bits (641), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 65/270 (24%), Positives = 119/270 (44%), Gaps = 17/270 (6%)

Query: 3   VAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSAQL 59
           +A  QF         N +    ++A+AA   A L  LPE      + +       + A+ 
Sbjct: 15  LALVQFESVLCDPAANTQKACRMIAEAAAEGADLVVLPELFSTGYELNIVGPHVPELAEP 74

Query: 60  LEGEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
           ++G  +  L+  ++      +  +       G  +N  V +   G ++  Y K HL+   
Sbjct: 75  VDGPTVRALQDAARAGNCYVVAGLALAYDMAGVPFNSSVVIDRQGELLGTYDKQHLWAL- 133

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E     +G +  P+ + +  ++G+M CYD+ FPE+A   ALQGA++++ P+AW +  
Sbjct: 134 ---ERFYFRSGCD-CPVFDTDFGRIGVMICYDMGFPEVARMLALQGADLILCPSAWCQE- 188

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAA-ASEMPALI 232
                W     ARAL+ T ++ A    G ++     G +++ +P G  +A  A E   ++
Sbjct: 189 -DMDVWDVNAPARALENTAFVAAVNRYGVEDQLVMPGHTKVCNPRGHVVAELAEEAEGVL 247

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
             E+    V   R + P L +RR     L+
Sbjct: 248 HVELDLNEVVDYRQRSPYLRDRRPDLYDLV 277


>UniRef50_Q12ZA5 Carbon-nitrogen hydrolase family protein n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12ZA5_METBU
          Length = 270

 Score =  250 bits (640), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 73/269 (27%), Positives = 122/269 (45%), Gaps = 17/269 (6%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +AA Q  +     +KN +       +A    A +  LPE       +  +     A+ 
Sbjct: 10  IKIAAIQMDICHCNKQKNIKKALHFSEEAISKGADIIVLPEVFSTGFCY--EELENIAES 67

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVP-STPGR--AWNMLVALQAGNIVARYAKLHLYDA 116
                +  L   SK+N    + +I    S+  R    N+   L+ G +V  Y K H +  
Sbjct: 68  GSYPTIKELEVFSKKNKCIIVGSIIEKHSSKNRETYTNLGFCLEDGELVGTYTKTHPFG- 126

Query: 117 FAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
              +E     +G+ I P+ L+   + VGL  CY++RFPE+A    L GA+IL+  A +  
Sbjct: 127 ---KEKEYFTSGDVIEPIHLKERDLTVGLQICYEMRFPEIARKLCLSGADILMTIAEFPN 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPAL 231
              +EH W TL  ARA++   + +A    G+       G S IIDP G  IA A +   +
Sbjct: 184 P--REHQWRTLATARAIENQVFHIACNRSGSDPTSTFFGGSMIIDPLGNVIADAKDGECV 241

Query: 232 IMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           I+ E+    +++ R ++PV ++RR    +
Sbjct: 242 IIEEIDTSIMKKTRKEIPVFDDRRPDIYK 270


>UniRef50_Q972L1 281aa long hypothetical beta-ureidopropionase n=1 Tax=Sulfolobus
           tokodaii RepID=Q972L1_SULTO
          Length = 281

 Score =  250 bits (640), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 59/270 (21%), Positives = 102/270 (37%), Gaps = 15/270 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADL--SVKSAQ 58
           + +A  Q       E N +        A ++ A L    E    +     +       A+
Sbjct: 5   VKIAMIQMGSVESKEANIQKALEYTKAAVKDGAELIVYNELFTTQYFPATEDPKFFDLAE 64

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQAGNIVARYAKLHLYDA 116
             +G  +      SK+  +  I+TI        G  ++  + ++ G ++ +Y K H+   
Sbjct: 65  PEDGPTVRVFAEFSKQYKIGMIITIFEEDKKIKGIYYDTAIFIKDGKVLGKYRKTHIPQV 124

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
               E      G E  P+ +  G K+G + CYD  FPE      L+GA+I+ +P      
Sbjct: 125 PGYYEKFYFKPGKEY-PVFDFGGYKIGAVICYDRHFPEGVRILTLKGADIVTIPTTTNFY 183

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGEC-----GNK--NIGQSRIIDPFGVTIAAASEMP 229
           P     W   L A A   T Y+V          G +    G+S + DP G  +   S   
Sbjct: 184 P---ETWELELRAHAAFNTIYVVGVNRTPEIFQGKEIDYFGKSLVADPTGNILKEMSSQE 240

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
              + +V  + +R+ R + P L +R+    
Sbjct: 241 GYEIVDVNLDFIRERRKKAPFLRDRKPENY 270


>UniRef50_C7ICC9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Clostridium papyrosolvens DSM 2782
           RepID=C7ICC9_9CLOT
          Length = 267

 Score =  250 bits (638), Expect = 5e-65,   Method: Composition-based stats.
 Identities = 71/262 (27%), Positives = 122/262 (46%), Gaps = 16/262 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +   Q  V+   + N E   S++ + ++  A +  LPE  +    +D  L    A+ +
Sbjct: 5   IRLGLCQMTVSDKKKDNLEKALSMLEECSKQGADIAILPEMFIC--PYDTKLFPLYAENV 62

Query: 61  E-GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLV-ALQAGNIVARYAKLHLYD--- 115
           E  + L  + + +K N M  +      S  G  +N  V   + GN +A++ K+HL+D   
Sbjct: 63  ENSKTLSVISKSAKYNNMYIVAGTIPESNNGFIYNSSVMFDRQGNTIAKHRKVHLFDINV 122

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES  + AG     + E E   +GL  C+D+RF  L      +GA+I++ PA++
Sbjct: 123 KDGISFRESDVLTAGRS-VTVAETEFGCIGLAICFDMRFAGLYSEMTEKGAKIIITPASF 181

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW  L+ ARALD   + VA       +      G S + DP+G  I+ A E 
Sbjct: 182 NM-TTGPAHWELLVRARALDNQVFHVAVSSARETSANYVSYGNSMVCDPWGSVISRAEEK 240

Query: 229 PALIMAEVTPERVRQVRAQLPV 250
             +++A++    V  VR Q+PV
Sbjct: 241 EDILIADIDLNMVNSVRNQIPV 262


>UniRef50_A6DKQ0 Carbon-nitrogen hydrolase family protein n=1 Tax=Lentisphaera
           araneosa HTCC2155 RepID=A6DKQ0_9BACT
          Length = 286

 Score =  249 bits (636), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 71/274 (25%), Positives = 118/274 (43%), Gaps = 16/274 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQL 59
            +A  Q       E N +    L+A AA++ A++    E  L+            + AQ 
Sbjct: 3   KLALLQSRDYGSPEANKKQHLKLIADAAKSGANIICTQELFLSNYFCREQNTEHFQYAQK 62

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
           ++ E L   ++ +K + +   L+    +  G  +N  V +   G  + +Y KLH+     
Sbjct: 63  IDQELLADFQQCAKNHGVVLALSFFEEALNGVYYNTSVIIDADGTYLGKYRKLHIPQDPY 122

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +E      GN   P+ E +  K+ L+ C+D  FPE A    L GAEI+++P A    P 
Sbjct: 123 FEEKFYFTPGNLGVPVFETQFGKISLIICWDQWFPETARLACLAGAEIILVPTAIGWLPD 182

Query: 179 -KEHH-------WSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAA- 225
            KE H       W+ +    A+   CY  A    G +      GQS I D +G T+A A 
Sbjct: 183 EKEEHGAQQAHSWTQVQLGHAVANGCYYAAVNRVGIEEPIQFWGQSFISDFYGQTLAQAS 242

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           S    ++ A++  +++R+ R   P   +RR    
Sbjct: 243 SNEEEILFADLDLKQLREHRQIWPFFRDRRIDAY 276


>UniRef50_A6VWN8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Marinomonas RepID=A6VWN8_MARMS
          Length = 277

 Score =  249 bits (636), Expect = 8e-65,   Method: Composition-based stats.
 Identities = 79/276 (28%), Positives = 126/276 (45%), Gaps = 23/276 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q   T  W+ N      L+A AA + A L  LPE +     H   +   +    
Sbjct: 4   LCVAAIQLTSTISWQDNLREVKHLVASAARDGARLVVLPENVFLF--HGKGMRCLAESDD 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP--------STPGRAWNMLVALQAGNIVA-RYAKL 111
           +      +   ++ + +  ++  H              R       +    ++  RY K+
Sbjct: 62  QSVIFKEISALAQEHSIYLVVGSHPSLLRPSGDLVVDERVRQTCWVIGPDGLLYERYDKI 121

Query: 112 HLYD------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
           HL+D      A + +ES  ++ G     +++V+G KVGL  CYDLRFPEL       GAE
Sbjct: 122 HLFDVTVDDKATSYKESGVIEPGELALKVIDVDGFKVGLSICYDLRFPELYRELTKLGAE 181

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGV 220
           +L++PAA+     K  HW  LLAARA++  CY++  G+CG      +  G S +  PFG 
Sbjct: 182 VLLVPAAFTYVTGK-AHWDILLAARAIENQCYVLGVGQCGWHNETRQTYGHSVLYSPFGE 240

Query: 221 TIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            +A   E P   +  +T   +   R ++P L++RR 
Sbjct: 241 RLANLEEEPGYFVFNMTKTALSNCRQKMPCLSHRRL 276


>UniRef50_A1RZK0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RZK0_THEPD
          Length = 286

 Score =  249 bits (636), Expect = 8e-65,   Method: Composition-based stats.
 Identities = 81/261 (31%), Positives = 129/261 (49%), Gaps = 7/261 (2%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSAQ 58
           + VA  Q AV+    +N E    L+      DA L   PE L+  D      D   + A+
Sbjct: 16  VRVALHQLAVSGEKRENLEKALRLLEL---GDAYLHVFPEYLMGVDPGGPTRDYVWRVAE 72

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
            ++GEF  R+  ++    +  + T+ +   PG  +N  V  + G + A Y K+HL+DA+ 
Sbjct: 73  PIDGEFASRIVEKTGELGVAAVFTMFLREGPG-VYNAAVLAEEGKVKAVYRKIHLFDAYG 131

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +ES     G E   + +++G+++G+  C+DLRFPEL  +  L+GAE+ V+P+AW RGP 
Sbjct: 132 YRESSVFSPGREPV-VADLKGLRLGIAVCFDLRFPELFRSMFLRGAEVFVVPSAWYRGPY 190

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K   W  L AARA + T Y+VA  + G    G S +  P G  +    E    I  ++  
Sbjct: 191 KVEQWKALTAARAHENTSYLVAVNQVGESFTGHSLVATPLGHLLVDLGEGERSIAVDLDE 250

Query: 239 ERVRQVRAQLPVLNNRRFAPP 259
             +   R ++PV +  R    
Sbjct: 251 GELASARERIPVRDLLRLELY 271


>UniRef50_O94660 Probable hydrolase nit2 n=2 Tax=Schizosaccharomyces
           RepID=NIT2_SCHPO
          Length = 276

 Score =  248 bits (635), Expect = 9e-65,   Method: Composition-based stats.
 Identities = 83/274 (30%), Positives = 130/274 (47%), Gaps = 19/274 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L A  Q   +    KN  IC  L++QAA   A     PEA      H++D +++     +
Sbjct: 3   LAAVAQLNSSGSILKNLAICKELISQAAAKGAKCIFFPEASDFI-AHNSDEAIELTNHPD 61

Query: 62  -GEFLGRLRRESKRNMMTTILTIHVPST-PGRAWNMLVALQA--GNIVARYAKLHLYD-- 115
             +F+  +R  + ++ +   + +H PS    +  N  + ++   G I++RY+K HL+D  
Sbjct: 62  CSKFIRDVRESATKHSIFVNICVHEPSKVKNKLLNSSLFIEPLHGEIISRYSKAHLFDVE 121

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                 ++ES     G  I P  +    KVG   C+D+RFPE A+     GA I+  P+A
Sbjct: 122 IKNGPTLKESNTTLRGEAILPPCKTPLGKVGSAICFDIRFPEQAIKLRNMGAHIITYPSA 181

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +        HW  LL ARALD+ CY++A  + G  N      G S I+DP+G  IA  S+
Sbjct: 182 FTE-KTGAAHWEVLLRARALDSQCYVIAPAQGGKHNEKRASYGHSMIVDPWGTVIAQYSD 240

Query: 228 M---PALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
           +     LI A++    V  VR  +P+L      P
Sbjct: 241 ISSPNGLIFADLDLNLVDHVRTYIPLLRRNDLYP 274


>UniRef50_A4SSL0 Beta-ureidopropionase n=2 Tax=Gammaproteobacteria
           RepID=A4SSL0_AERS4
          Length = 277

 Score =  248 bits (634), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 81/270 (30%), Positives = 121/270 (44%), Gaps = 17/270 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +AA Q      W+ N E  A+ +A        L  LPE   A           + ++ 
Sbjct: 1   MWLAAIQLVSGRHWQDNREQIAAELAALPAGRPLLVLLPENF-ALFGERQGYLDGAERIG 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAW---NMLVALQAGNIVARYAKLHLYDA- 116
           EG    +L   +K   +  +      + PG A    + LV   AG +   Y K+HL+D  
Sbjct: 60  EGPIQQQLAAWAKEYGIWLVAGAMPTAIPGSAHIHTSSLVFDPAGELKGHYHKIHLFDVD 119

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES     G +   L++     +GL  CYDLRFPEL    A  GA +L++PA
Sbjct: 120 VADNQGRYRESETFSPGQD-CVLIDSPFGPLGLSICYDLRFPELYRQLARAGARVLLVPA 178

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGE-----CGNKNIGQSRIIDPFGVTIAAAS 226
           A+      E HW  LL ARA++  CY+VAA +      G    G S +IDP+G  +A   
Sbjct: 179 AFTA-VTGEAHWEPLLRARAIENQCYVVAANQGGTHETGRHTWGHSMVIDPWGRVLACQP 237

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
              A ++A + PE   +++  +PVL + R 
Sbjct: 238 SGRATVLAAMDPELGDELKRTMPVLQHARL 267


>UniRef50_A1HQ26 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HQ26_9FIRM
          Length = 258

 Score =  248 bits (633), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 71/265 (26%), Positives = 108/265 (40%), Gaps = 14/265 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q  V      +N     +L  + A   A +  LPE              K A+ 
Sbjct: 1   MRIALVQMKVIAGAVAENRRRGLALAQEGAAR-ADVVVLPEIWTTGYALR--EVDKWAED 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
           +EG  +  +   S++     I         G+ +N  V +   GN+ A Y K+HL+    
Sbjct: 58  VEGLTISEMSNISRKYGAYIIAGSIPLRKNGKVYNGAVVIGPDGNVAAEYRKIHLFSMMG 117

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E R   AG+       ++G+  G+  CYDLRFPEL    AL GA+I+ LPA W     
Sbjct: 118 --EERFFAAGDRRCT-FNLKGVTAGIAICYDLRFPELFRVLALDGAQIVFLPAEWP--TA 172

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
           +  HW  L   RA++   ++      G        G S +I P G  +A   E   ++ A
Sbjct: 173 RGEHWHLLSRTRAIENQVFLCVVNCVGEHKGNPFYGHSMLIGPSGEVLAEGGEEETILYA 232

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
           E     V + R ++ V  +RR    
Sbjct: 233 EADFALVAKAREKMSVWQDRRPEVY 257


>UniRef50_A8MG18 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Bacteria RepID=A8MG18_ALKOO
          Length = 261

 Score =  248 bits (633), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 68/266 (25%), Positives = 108/266 (40%), Gaps = 12/266 (4%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M ++  Q  +T    E N +    L+  AA+ +    ALPE          +   +    
Sbjct: 1   MKISLIQMKMTFEDMEHNFKKAEELIRLAAKENPDTIALPETWSTGF-FPKENIKEFCDQ 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
                     + SK   +  I    +       +N        G  +A Y K HL+    
Sbjct: 60  NGNRTKRLFSKLSKELNVNIIAGSVINEKQDGIYNTSYIFNKQGECIAEYDKTHLFSYMG 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E +  + G+    + E++G+K G++ CYD+RF EL    ALQ  +IL + A W    L
Sbjct: 120 --EDQYFEKGS-GITVFELDGIKCGIVICYDIRFVELVRTLALQEIKILFVVAQWPM--L 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
           + HHW  L  ARA++   ++     CG        G S +IDP+G  I  AS    +I  
Sbjct: 175 RIHHWQILNEARAIENQIFVACVNSCGRAGETIYGGNSALIDPWGEVILRASNQEEIITG 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
            +    V ++R  + V  +RR    Q
Sbjct: 235 NLDLSIVEKIRDTIHVYKDRRPDLYQ 260


>UniRef50_C4XZI3 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
           42720 RepID=C4XZI3_CLAL4
          Length = 344

 Score =  247 bits (631), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 71/278 (25%), Positives = 114/278 (41%), Gaps = 22/278 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAEN----DASLFALPEALLARDDHDADLSVKS 56
           + VA  Q    +    N     S + +A          +  LPE       +  D   + 
Sbjct: 58  LKVALIQLKAGADKAANLSKVQSYIDKAVSESTIGKPDVVMLPECF--NSPYAVDKFREY 115

Query: 57  AQLLEG-EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLY 114
           A+++ G E    L + +KR+ +  +      S   + +N  +     G+I+A++ K HL+
Sbjct: 116 AEVIPGGETTKFLAQLAKRHGVFIVGGSFPESDQDKIYNTSLTFSPSGDIIAKHRKAHLF 175

Query: 115 D-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQ--GAEIL 167
           D         +ES  + AG++       +   VGL  CYD+RFPELA+A +     A  +
Sbjct: 176 DIDIPNGITFKESITLSAGDKATVFGLGDFGTVGLGICYDIRFPELAMAASRAPHNAFAM 235

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC------GNKNIGQSRIIDPFGVT 221
             P A+        HW  L  ARA+D   + V           G +  G S ++DP G  
Sbjct: 236 FYPGAFNT-TTGPLHWHLLARARAVDNEVFTVLCSPARDVGGSGYQAYGHSLVVDPSGKI 294

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           IA A E   ++ AE+    +   R  +PV   RRF   
Sbjct: 295 IAEAGEGEEILYAELDHSLLPSARTGIPVHYQRRFDIY 332


>UniRef50_B6K212 UPF0012 hydrolase n=1 Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6K212_SCHJY
          Length = 334

 Score =  247 bits (631), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 64/272 (23%), Positives = 112/272 (41%), Gaps = 15/272 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
             +   Q         N +   + + +AA+N A++  LPE   +     H  + +     
Sbjct: 49  FRLGLVQLLSGMDKMDNLKNARTKVLEAAKNGANIVVLPEIFNSPYSVAHFREYAEDFVT 108

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD-- 115
                    L + +K   +       V     + +N  +     G+++ ++ K+HL+D  
Sbjct: 109 TSHSPSYDALSQMAKDAKVYLFGGSIVELDNDKVYNTALVFSPDGSLLGKHRKMHLFDVD 168

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                   ES  +  GN +  + + E  K G+  CYD+RFPELA+  A  G   ++ P+A
Sbjct: 169 IPNGIRFIESEVLSPGNAMTMV-QTEFGKFGMGICYDIRFPELAMIAARNGCAGMIYPSA 227

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASE 227
           +        HW  L  +RA+D   ++       N        G S  +DP+G  +A A E
Sbjct: 228 FNT-TTGPLHWELLARSRAVDNQIFVALCSPARNMDASYHAYGHSMAVDPYGKILAEAQE 286

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            PA+I A++ P  +   R  +P+   RRF   
Sbjct: 287 GPAIIYADINPTTMEVCRRAIPLYTQRRFDMY 318


>UniRef50_Q3SLE9 Carbon-nitrogen hydrolase n=101 Tax=Proteobacteria
           RepID=Q3SLE9_THIDA
          Length = 319

 Score =  246 bits (630), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 76/272 (27%), Positives = 124/272 (45%), Gaps = 17/272 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q A       N      L+  A +  A L  LPE        D+ +        
Sbjct: 29  VRVAAIQMASGPSVPANLAEAERLIELAVQAGARLVVLPEFFCIMAMKDSYVVKAREAEG 88

Query: 61  EGEFLGRLRRESKRNMMTTILTIH--VPSTPGRAWNM-LVALQAGNIVARYAKLHLYDA- 116
           +G     L R +K++ +  I        S P +  N  LV  + G  +ARY K+HL+   
Sbjct: 89  DGPIQTFLARMAKKHKVWLIGGSVPLEASVPNKVRNSCLVYDERGKQIARYDKIHLFGLD 148

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 QE++ ++ G+++  ++     ++GL  CYDLRFPEL  A      +I+V+P+A+
Sbjct: 149 LGNERYQEAKLIEPGDKVV-VVNSPFGRIGLSVCYDLRFPELYRAM--PDVDIIVVPSAF 205

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGE-----CGNKNIGQSRIIDPFGVTIAAASEM 228
                   H+ TL+ ARA++   Y++A  +      G +  G S I+DP+GV +      
Sbjct: 206 TA-TTGRAHFETLVRARAIENLAYVIAPAQGGYHLSGRETHGDSMIVDPWGVVLDRLPRG 264

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
             +++A + P     +R  LP L + RF P Q
Sbjct: 265 SGVVIANINPAYQASLRKSLPALQH-RFIPCQ 295


>UniRef50_A7IJX5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=101 Tax=Alphaproteobacteria RepID=A7IJX5_XANP2
          Length = 310

 Score =  246 bits (629), Expect = 6e-64,   Method: Composition-based stats.
 Identities = 84/269 (31%), Positives = 132/269 (49%), Gaps = 15/269 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A  Q         N +   +L+ +AA + A     PE     +   A L  K  +  
Sbjct: 25  LRIALVQLRSGRDPAANLDATVALVREAARDGARYVQTPEVTNLMELDRAVLFEKLREEA 84

Query: 61  EGEFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
           +   L  LR+ ++   +   I ++ +  +  +A N    +   G I+ARY K+H++D   
Sbjct: 85  DDATLKALRQLAQELGIFLHIGSLALKVSDKKAVNRAFMVGPDGEIIARYDKIHMFDVDL 144

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES     G E A L  V   + GL  CYDLRFP L  A A  GA++L +P+A+
Sbjct: 145 GNGESYRESSAYRPG-ERAILANVGAFRFGLTICYDLRFPSLYRALAEGGAQVLTVPSAF 203

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASEM 228
            R P  E HW  LL ARA++   Y++AA + G      +  G S ++DP+G  IA     
Sbjct: 204 TR-PTGEAHWHVLLRARAIENGAYVLAAAQGGKHENGRETFGHSLVVDPWGRVIAEGGAD 262

Query: 229 PALIMAEVTPERVRQVRAQLPVLNN-RRF 256
           P +I+AE+  + V   RA++P L+N RRF
Sbjct: 263 PGVILAEIDLKEVAAARARIPSLSNGRRF 291


>UniRef50_A0PVY5 Amidohydrolase n=12 Tax=Actinomycetales RepID=A0PVY5_MYCUA
          Length = 280

 Score =  246 bits (629), Expect = 6e-64,   Method: Composition-based stats.
 Identities = 88/276 (31%), Positives = 132/276 (47%), Gaps = 22/276 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q    +    N E+      +AA+  A L   PEA + R           AQ L
Sbjct: 1   MRIALAQILSGTDPTANLELVRDYAERAADAGARLVVFPEATMCRFGVPLG---PVAQPL 57

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG---NIVARYAKLHLYDAF 117
           +G +   +RR + +  +T +  +  P+  GR  N L A   G        Y K+HLYDAF
Sbjct: 58  DGPWANGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKIHLYDAF 117

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              ESR V  G+E   ++ V+  +VGL  CYD+RFP L    A +GAE++V+ A+W  GP
Sbjct: 118 GFAESRTVAPGHEPV-VITVDDFQVGLTVCYDIRFPALYTELARRGAELIVVSASWGSGP 176

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECG--------------NKNIGQSRIIDPFGVTIA 223
            K   W+ L  ARALD+  Y+ AAG+                 + +G S +  P G  +A
Sbjct: 177 GKLDQWTLLARARALDSASYVAAAGQADPGDTASDPGGGSGAPRGVGGSLVTSPLGEVVA 236

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNR-RFAP 258
           +A   P L++A++   +V   R  + +L N+ RF  
Sbjct: 237 SAGSDPQLVVADIDLAKVGAARDNIGMLRNQSRFTQ 272


>UniRef50_A0JSW0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Actinomycetales RepID=A0JSW0_ARTS2
          Length = 294

 Score =  246 bits (628), Expect = 7e-64,   Method: Composition-based stats.
 Identities = 85/266 (31%), Positives = 127/266 (47%), Gaps = 17/266 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q        +N +I      +A +  A L   PEA +    +     +  A+ L
Sbjct: 31  VRVALAQIVTGRDISRNLDIVEKYARKAKKGGAQLVVFPEATMRAFGNS---LLDIAEPL 87

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +G +  R+R  ++   +  +  +  P    +  N L+    G + A Y K+HL+DAF   
Sbjct: 88  DGPWATRVRHIAREADIVIVAGMFTPGGGRKVRNTLLVTGPG-VEASYDKIHLFDAFGFA 146

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES  VDAG   A   E+ G+K GL TCYD+RFP L  A A  GAE  ++ A+W  GP K 
Sbjct: 147 ESDTVDAGTR-ASTFELGGIKFGLATCYDIRFPALFTANADLGAEANIVCASWGSGPGKV 205

Query: 181 HHWSTLLAARALDTTCYMVAAGECG------------NKNIGQSRIIDPFGVTIAAASEM 228
             W  L  ARA+DTT Y++A G+                 +G S ++ P G  +      
Sbjct: 206 DQWRLLARARAVDTTTYVLACGQADPATEGIETKGSAPTGVGHSAVVSPLGEVLEELDAG 265

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNR 254
             L+ A++ P  V++ RA+LPVL NR
Sbjct: 266 TGLMFADLDPAVVKEARAKLPVLANR 291


>UniRef50_C6N396 Nitrilase n=2 Tax=Legionella RepID=C6N396_9GAMM
          Length = 286

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 72/265 (27%), Positives = 130/265 (49%), Gaps = 14/265 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  Q   ++   +N +    LM QA E+DA L  LPE       H+ D         +
Sbjct: 17  RVALAQMVSSANVVENLQQVEKLMIQAREDDAQLVLLPENFAFMGRHETDKLHIGEVYGQ 76

Query: 62  GEFLGRLRRESKRNMMTTILT-IHVPSTPGRAW-NMLVALQAGNIVARYAKLHLYDA--- 116
           G    ++ + +K+  +  +   + +  +  +   + LV  + G   ARY K+HL+D    
Sbjct: 77  GPIQEKISQLAKQLGLWVVAGTMPLKGSGSKVRASCLVYDEQGLCAARYDKIHLFDVSVS 136

Query: 117 --FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              A  ES  ++ G+++  +++    K+GL  CYDLRFPEL     +QGA++  +P+A+ 
Sbjct: 137 PQEAYCESATIERGHDLV-VVDTPVGKIGLTVCYDLRFPELYQQLLIQGAQLFTVPSAFT 195

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  LL ARA++   Y++AA + G+        G S II+P+G  +A  ++  
Sbjct: 196 A-VTGLAHWEVLLRARAIENLSYVLAANQGGHHENGRSTYGHSMIIEPWGAVLAQQADGI 254

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNR 254
            ++ AE+  + ++ +R   P +++ 
Sbjct: 255 GVVTAEIDLQGLQHLRKTFPSVDHH 279


>UniRef50_D0LZ94 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Bacteria RepID=D0LZ94_HALO1
          Length = 296

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 86/287 (29%), Positives = 139/287 (48%), Gaps = 30/287 (10%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +AA Q       +KN E+C   +A AA   A +  LPE   A   H     + +A+LL
Sbjct: 10  FRLAALQMCAGDDRDKNLELCDRQVAAAASAGAEMVVLPENF-AYLGHSEGDRMAAAELL 68

Query: 61  E----GEFLGRLRRESKRNMMTTILTIHVPSTPGR-----------AWNMLVALQAGN-I 104
           +    G  L  L+R +  + +  +        P R           A+N  V +  G  +
Sbjct: 69  DEREPGPILAALKRMATVHGVWLVGGGMAERIPEREVKDGIDPDKQAFNTCVVVAPGGAL 128

Query: 105 VARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQ 159
           V+RY K+HL+D       +++ES    AG+EI  + E    ++GL  CYDLRFPE+  A 
Sbjct: 129 VSRYRKIHLFDADIPDGPSLRESSGTVAGHEIG-VCETPLARLGLTVCYDLRFPEIYRAL 187

Query: 160 AL-QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSR 213
            + +GAE++V+P+A+        HW  LL ARA++  C++VAA + G  N      G + 
Sbjct: 188 CVHEGAELVVVPSAFTA-RTGAAHWHVLLRARAIENQCFIVAAAQVGQHNERRNSYGHAL 246

Query: 214 IIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           I+DP+G  +A   +   L +A++    + Q R ++P   +    PP+
Sbjct: 247 IVDPWGTILAEVEDGEGLAIADIDLALIEQTRQRMPCHQHAVLLPPE 293


>UniRef50_O31664 UPF0012 hydrolase mtnU n=96 Tax=Bacilli RepID=MTNU_BACSU
          Length = 259

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 64/260 (24%), Positives = 113/260 (43%), Gaps = 14/260 (5%)

Query: 2   LVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            ++  QF ++     +N +     + +     A +  LPE       +D     + A   
Sbjct: 4   TISCLQFDISYGKPSENIKKAEFFIEK-ESKHADVLVLPELWTTG--YDLANLDELADED 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAI 119
                  L++ +K++ +  +            +N +      G I+  Y K HL+    +
Sbjct: 61  GRSAQSWLKKTAKKHGVHIVAGSVAVRKNSDVYNTMYIADKEGQIIKEYRKAHLFQL--M 118

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E   + AG+E     E++G+K   + CYD+RFPE       +GA +L + A W    L 
Sbjct: 119 DEHLYLSAGSEDG-YFELDGVKSSGLICYDIRFPEWIRKHTTKGANVLFISAEWPLPRL- 176

Query: 180 EHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAE 235
             HW +LL ARA++  C++ A    G    N+  G S IIDP+G  +A       ++ AE
Sbjct: 177 -DHWKSLLIARAIENQCFVAACNCTGSNPDNEFAGHSLIIDPWGRVLAEGGREEGIVRAE 235

Query: 236 VTPERVRQVRAQLPVLNNRR 255
           +  +   +VR  +PV ++ R
Sbjct: 236 IDLQESAEVRESIPVFDDIR 255


>UniRef50_A7GE66 Hydrolase, carbon-nitrogen family n=24 Tax=cellular organisms
           RepID=A7GE66_CLOBL
          Length = 278

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 70/274 (25%), Positives = 127/274 (46%), Gaps = 15/274 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSA--Q 58
           + +A  Q  V    +KN +    ++ +A + + ++  LPE      ++           +
Sbjct: 4   LKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYENKCFKPYGEIINE 63

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD-- 115
              GE +  +++ +K   +  +          + +N  +V    G ++A++ K+HL+D  
Sbjct: 64  ENGGETVKAIKKAAKDLELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDID 123

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES  + AGN+I  L      K+G+M CYD+RFPEL+   A++GA+I+  PAA
Sbjct: 124 VKGGVTFKESDTLTAGNKIT-LFNTPWGKLGVMICYDIRFPELSRIMAVKGAKIIFTPAA 182

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +        HW TL  +RALD   YMV      ++N      G S I  P+G  +A    
Sbjct: 183 FNM-TTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLDA 241

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
              ++ +E+  +   ++R +LP+L + R     L
Sbjct: 242 KEDILFSEIDLDYESKIREELPLLKHIRKDIYSL 275


>UniRef50_Q2JDM2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=43 Tax=cellular organisms RepID=Q2JDM2_FRASC
          Length = 404

 Score =  245 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 83/263 (31%), Positives = 120/263 (45%), Gaps = 12/263 (4%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +  A  Q       E  A+    ++ +  +  A L  LPE  +    H  D     A+ L
Sbjct: 5   VRAAVLQLGC-PDEENAADRVRRVLGEIRQTQADLVVLPELWVTGYFH-FDRYEAEAEAL 62

Query: 61  EGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            G  +  LR  ++      +   I   S  GR +N  V +   G I   Y K+HL+  + 
Sbjct: 63  TGPTVTALREAARERGCHLVAGSIVERSADGRLFNTTVLIGPDGMIRHAYRKVHLF-GYG 121

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E+R +  G  +  +   E   VGL TCYDLRFPEL    A  GAEI+V+ +AW    L
Sbjct: 122 SAEARLLTPGATVGTV-PTELGIVGLATCYDLRFPELFRLLAEGGAEIVVVVSAWPLARL 180

Query: 179 KEHHWSTLLAARALDTTCYMVAAG----ECGNKNIGQSRIIDPFGVTIAAASEMPALIMA 234
              HW  L   RA++   Y+VA      + G +  G S ++DP+G  +A A   P  + A
Sbjct: 181 --DHWRVLTRTRAIENQVYLVACNAAGRQAGREMAGASVVVDPWGEVLAEAGPRPTTVRA 238

Query: 235 EVTPERVRQVRAQLPVLNNRRFA 257
           E+ P R   VRA+ PVL +RR  
Sbjct: 239 ELDPSRPAAVRAEFPVLTHRRLG 261


>UniRef50_A5G317 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Alphaproteobacteria RepID=A5G317_ACICJ
          Length = 284

 Score =  244 bits (624), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 83/281 (29%), Positives = 126/281 (44%), Gaps = 27/281 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAEND-ASLFALPEALLARDDHDADLSVKSAQL 59
           + ++  Q    +    N      L+  A   D   L +LPE        D     ++A++
Sbjct: 7   LRLSVIQMTPGAEKGANIAQARGLIDAAVAADRPGLVSLPEVWSCLGG-DRAAKTEAAEV 65

Query: 60  LE--------GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAK 110
           L         G+    LR  ++R+ +             R +N  LV    G  +ARY K
Sbjct: 66  LPAAGSGETGGDAYEFLRETARRHRIHVHGGSIGEQGGDRLYNTTLVFDPDGREIARYRK 125

Query: 111 LHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
           +HL+D         +ES    AG+       + G+ VGL  CYD+RFPEL LA    GA+
Sbjct: 126 IHLFDITTPDGQGYRESATYGAGD-AVVTCRIGGLTVGLSICYDMRFPELYLALHRAGAD 184

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK---------NIGQSRIID 216
           ++++PAA+     K+ HW  LL ARA++T C++ AA   G             G S I D
Sbjct: 185 LIMVPAAFTLQTGKD-HWDVLLRARAIETQCWIAAAACVGPHRDGRGETRFTYGNSLIAD 243

Query: 217 PFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
           P+G  +A  S+ P    A + P R  +VR  +PVL +R+ A
Sbjct: 244 PWGSIVARVSDGPGFATARIDPARGAKVRRDMPVLEHRKLA 284


>UniRef50_D2RS34 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RS34_9EURY
          Length = 277

 Score =  243 bits (622), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 81/274 (29%), Positives = 127/274 (46%), Gaps = 23/274 (8%)

Query: 1   MLVAAGQFAVTSV-WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  V     ++N E     +++AAE  A L ALPE          D   + A+ 
Sbjct: 9   LRLALAQLEVEPTAVDENVERALEAISRAAERGADLVALPELFNVGY-FAFDSYNRLAEP 67

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHV-----------PSTPGRAWNMLVALQAGNIVARY 108
           LEGE L RLR  +  + +  +    V           P+  G A    +    G +   Y
Sbjct: 68  LEGETLTRLREAAADHEIAVLAGSIVEDLAATETADTPAEEGLANTAALFDADGGLQLVY 127

Query: 109 AKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
            K HL+  +   ES  +  G  I     V G+ VG  TCYDLRFPEL       GAE+++
Sbjct: 128 RKHHLF-GYQSAESELLVPGERI-ETATVAGVPVGATTCYDLRFPELYRRLIDAGAELVL 185

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN------KNIGQSRIIDPFGVTI 222
           +P+AW     +  HW TL  ARA++   ++      G         +G+S + DP+G T+
Sbjct: 186 VPSAWPYP--RIEHWETLSRARAIENQAFVATINGSGRFPDEDATLLGRSTVYDPWGTTL 243

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           A++ + P L++A++    V ++R + P L +RR 
Sbjct: 244 ASSGDDPTLVVADLDLGAVDRIREEFPALRDRRL 277


>UniRef50_P47016 Probable hydrolase NIT2 n=9 Tax=Saccharomycetaceae RepID=NIT2_YEAST
          Length = 307

 Score =  243 bits (622), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 82/297 (27%), Positives = 137/297 (46%), Gaps = 44/297 (14%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEA--LLARDDHDADLSVKSAQL 59
            VA  Q   ++   KN ++   L+++A +  A +  LPEA   L+++   +    + +  
Sbjct: 7   RVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPK 66

Query: 60  LEGEFLGRLRRESKRN--MMTTILTIHVP-------STPGRAWNMLVALQ-AGNIVARYA 109
              +    +    + N   +   + +H+P           R  N+L+ +   G I+  Y 
Sbjct: 67  FIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQ 126

Query: 110 KLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA 164
           KLHL+D        ++ES+ V  G  I  ++E    K+G   CYD+RFPE +L     GA
Sbjct: 127 KLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGA 186

Query: 165 EILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG------------------- 205
           EIL  P+A+      E HW  L  ARA+DT CY++  G+ G                   
Sbjct: 187 EILCFPSAFTI-KTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALE 245

Query: 206 ----NKNIGQSRIIDPFGVTIAAASE---MPALIMAEVTPERVRQVRAQLPVLNNRR 255
                ++ G S +IDP+G  IA A      P LI+A++  E ++++R ++P+ N RR
Sbjct: 246 KSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRR 302


>UniRef50_C0GEE7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GEE7_9FIRM
          Length = 261

 Score =  243 bits (621), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 70/263 (26%), Positives = 119/263 (45%), Gaps = 14/263 (5%)

Query: 1   MLVAAGQFAVTSV--WEKNAEICASLMAQ--AAENDASLFALPEALLARDDHDADLSVKS 56
           M VA  Q  V+ V   E+  +    +M +  A      L  LPE   +      D +  S
Sbjct: 1   MNVAIIQLEVSDVHSREERFKKVEQIMLELHAGNPQPDLILLPEIWGSGFFRFQDYAAHS 60

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD 115
            +  EGE    L   +++     +    V       +N  + +   G ++++Y K+HL+ 
Sbjct: 61  EE-AEGETYSFLAPWAEKMNCHILGGSIVERDGNHLYNTALFIDPHGKLISKYRKIHLF- 118

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
            +  +ES+ +  G     +++ +    G+ TCYDLRFPEL    A  GA+  ++ +AW  
Sbjct: 119 GYKSEESKLLTRGTT-PTVIKTDLGTFGISTCYDLRFPELYRKMADLGAQAFLVTSAWPL 177

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPAL 231
             L   HW+     RAL+  CY+++    G    N   G S ++DP+G  + +A E PAL
Sbjct: 178 ARL--EHWTLFNRTRALENQCYLISCNCSGQIKENPFAGNSMMVDPWGTVLHSAGEEPAL 235

Query: 232 IMAEVTPERVRQVRAQLPVLNNR 254
           +   +    V ++R   P  N+R
Sbjct: 236 LHGSIDLSHVSEIRDSFPAFNDR 258


>UniRef50_D0L1I4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Halothiobacillus neapolitanus c2
           RepID=D0L1I4_HALNC
          Length = 294

 Score =  243 bits (621), Expect = 5e-63,   Method: Composition-based stats.
 Identities = 84/282 (29%), Positives = 129/282 (45%), Gaps = 30/282 (10%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQL 59
            +AA Q    + W +N  + A L++ AAE  A +  LPE    +  + H+       A+ 
Sbjct: 14  KIAAIQLNGKATWAENQPVIARLVSDAAEAGAEVIVLPENLYAMPANPHELLALGLGAEG 73

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHV-----PSTPGRAWNMLVALQ-AGNIVARYAKLHL 113
                L  L+  ++   +  +           S  G+ W+    +   G I A+Y K+HL
Sbjct: 74  ENAP-LDWLQTLARFKGVWLVAGTLPIRADGGSNEGKLWSRSYVIDSKGEIQAKYDKIHL 132

Query: 114 YD-------------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA 160
           +D             A + +ES +   G E+  L+E    ++G+  C+DLRFPEL     
Sbjct: 133 FDVDVPPRRSAQSATAESYRESDQFLHGTELV-LVETPAGRLGMAICFDLRFPELFRRLT 191

Query: 161 LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRII 215
            QGAE + LP+A+        HW  LL ARA++   YMVA+ +      G K  G S ++
Sbjct: 192 DQGAEWICLPSAFTE-TTGRAHWEPLLRARAIENQVYMVASAQVGVHASGRKTFGHSMVV 250

Query: 216 DPFGVTIAAASE-MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           DP+G  +A A       +MAE+  E    VR Q PVL+ RR 
Sbjct: 251 DPWGTVLANAKTLADCFVMAEIDAEAQAHVRQQFPVLDLRRL 292


>UniRef50_Q1LEX6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Cupriavidus metallidurans CH34
           RepID=Q1LEX6_RALME
          Length = 278

 Score =  243 bits (621), Expect = 5e-63,   Method: Composition-based stats.
 Identities = 86/271 (31%), Positives = 124/271 (45%), Gaps = 16/271 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q       E N       +  AA + A L   PE    R D +A  +  S   +
Sbjct: 4   IKVAAIQIDSRQDREANLAALEHWILAAASDGAKLIVTPEYSDVRGDANALQAAAS--AV 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLV-ALQAGNIVARYAKLHLYDAF 117
            G     +   ++R      L       PG  R  N  +     G I ARY K+HLYDA 
Sbjct: 62  PGPVSEHISSLAQRTGCWIHLGSMHERLPGETRLGNSGITFAPDGGIAARYRKVHLYDAV 121

Query: 118 A----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES     G+ +  + +  G+ +GL  CYDLRF EL      +GA +L++PAA+
Sbjct: 122 VNGKPYRESADFAPGDGLHTV-DAAGLTLGLSICYDLRFGELYRTLRARGANVLLVPAAF 180

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                ++ HW TLL ARA++  CY++AA + G        +G+S IIDP+G  +A   + 
Sbjct: 181 NVHTGRD-HWETLLRARAIENQCYVIAAAQIGGPGPALPCLGRSMIIDPWGTVLACMPDT 239

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
              I AE+  ERV  +R  LP   +RR    
Sbjct: 240 TGFITAELDTERVAGLREALPAWEHRRTDLY 270


>UniRef50_Q6SHH5 Carbon-nitrogen hydrolase family protein n=2 Tax=environmental
           samples RepID=Q6SHH5_9BACT
          Length = 255

 Score =  243 bits (620), Expect = 6e-63,   Method: Composition-based stats.
 Identities = 68/263 (25%), Positives = 114/263 (43%), Gaps = 16/263 (6%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A     +     EKN E     + QA  +   +  LPE        D     K A+L
Sbjct: 1   MKIATISLNIAWQDIEKNLERTEKFVRQAKADGCDVVVLPEVFNTGFIADVG---KYAEL 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
              +    L++ +  N++  +          +A N+ +   + GN VA+Y+KLH ++   
Sbjct: 58  PNCKTHHALQQFALNNLINIVAGASEKQPNEKAHNIALVFDSHGNEVAKYSKLHPFNY-- 115

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E +   +GNE     E++G+   +  CYDLRFPE+    A +  E++ + A W     
Sbjct: 116 ANEGKYFTSGNETIK-FELDGVACSVFICYDLRFPEIFRQIAEE-VEVIFVIANWPH--T 171

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIG-----QSRIIDPFGVTIAAASEMPALIM 233
           +E HW  LL ARA++  C++V     GN  +G      S +I+P G  +    +      
Sbjct: 172 REMHWQNLLIARAIENQCFIVGVNRIGNDGVGLKYNGSSMVINPLGEVLLQTDKKTEYAS 231

Query: 234 AEVTPERVRQVRAQLPVLNNRRF 256
            ++    V + R   P L + RF
Sbjct: 232 CDIDTLMVSKTRKDFPFLEDIRF 254


>UniRef50_A1WYY7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Proteobacteria RepID=A1WYY7_HALHL
          Length = 286

 Score =  242 bits (619), Expect = 7e-63,   Method: Composition-based stats.
 Identities = 78/268 (29%), Positives = 122/268 (45%), Gaps = 15/268 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VAA Q A     E N +    L+ +AA   A L  LPE        D D    +    +
Sbjct: 21  RVAAVQMASGPHVEANLQEAERLIGEAAAAGAELVVLPENFAIMGYQDTDKLKYAEPDGD 80

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNML-VALQAGNIVARYAKLHLYD--- 115
           G     L  +++R+ +  +         G  R      V    G  +A Y K+HL+D   
Sbjct: 81  GPIQAFLAEQARRHRIVLVGGTIPLQGEGPERVRPTAPVYGPDGGRLACYDKIHLFDVEV 140

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               A +ES     G     +++    ++G+  CYDLRFPEL    A QGAEI+ +P+A+
Sbjct: 141 APGEAYRESNTQQPGATPL-VVDTPVGRLGVAVCYDLRFPELFRELADQGAEIVAVPSAF 199

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAASEM 228
                 E HWS L+ ARA++   YMVA  +      G +  G+S ++DP+G  + +    
Sbjct: 200 TA-VTGEAHWSILVRARAIENLFYMVAPNQGGYHVNGRETHGESMVVDPWGRVMKSLERG 258

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
             +I  EV+  R+ ++R + P L +R+ 
Sbjct: 259 AGVITVEVSLSRLHEIRERFPALLHRKL 286


>UniRef50_Q1YU23 Hydrolase, carbon-nitrogen family protein n=1 Tax=gamma
           proteobacterium HTCC2207 RepID=Q1YU23_9GAMM
          Length = 281

 Score =  242 bits (619), Expect = 8e-63,   Method: Composition-based stats.
 Identities = 69/278 (24%), Positives = 124/278 (44%), Gaps = 23/278 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            + AA Q       ++N     +L+ QAAE  + L  LPE        D    V  A+  
Sbjct: 7   FIAAAVQLRPQQSLQQNLAAAGALIEQAAEAGSRLVVLPENFAYLGRKDL-TEVGLAEQS 65

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYDAF 117
            G     L ++++R+ +  +      S     R +         G++V  Y K+HL+D  
Sbjct: 66  TGPAYEFLAKQAQRHSLWLVGGTVPVSDANLSRPFARSWLFDPQGDLVQHYDKIHLFDVD 125

Query: 118 ------------AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
                         +ES    +   +  + E +  ++G+  CYDLRF EL    A   A+
Sbjct: 126 VPTSKEGILQQATYRESDDYRSAATVV-VAETDPCRLGMSVCYDLRFAELFRQLADADAQ 184

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGV 220
           ++ +PAA+     ++ HW  LL ARA++   +++ A      +      G S I+DP+G 
Sbjct: 185 VVAVPAAFTAATGRD-HWELLLRARAVENQLFVIGANMVDRDHPRRGLWGGSAIVDPWGN 243

Query: 221 TIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
            +A   +   + +AE+  +R+ ++RA++PV  +R+ A 
Sbjct: 244 VLARVDDEAGVAIAEINLDRLDEIRAKMPVAQHRKLAL 281


>UniRef50_C2BXL2 Cyanide hydratase n=1 Tax=Listeria grayi DSM 20601
           RepID=C2BXL2_LISGR
          Length = 268

 Score =  242 bits (618), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 74/265 (27%), Positives = 115/265 (43%), Gaps = 13/265 (4%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q  V     +KN +     + +AA + A +  LPE                A  
Sbjct: 10  MKIALCQTDVAFRDPDKNYQAIEQAVIEAANSGADIVVLPEMWNTGYCLS--ELADFADP 67

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFA 118
                 G L R + +  +T I      S      N++ A+ + G+++A Y K+H +    
Sbjct: 68  NGDRTKGFLIRLALQQKVTIIGGSVAISEEDHFSNIMYAVAKDGDLLASYRKVHPFQ--G 125

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E   +  GN  A L  +  +      CYD+RFPE     A  GAE+L + A W     
Sbjct: 126 MDEHTYIRPGNS-ANLFRIGDLACAGFICYDIRFPEWLRKHAANGAEVLFVSAQWPSA-- 182

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMA 234
           +   W  LL ARA++   ++VA    G    N+  G S +I P G  IA A + P  ++A
Sbjct: 183 RITQWKQLLIARAIENQAFVVAVNRVGSDPANQFGGNSLVIHPSGEIIAEADDTPQNLLA 242

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
           E+    V++VR  +PVL +RR    
Sbjct: 243 EINLADVKKVREAMPVLADRRPELY 267


>UniRef50_A4XQL4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=33 Tax=Proteobacteria RepID=A4XQL4_PSEMY
          Length = 286

 Score =  242 bits (618), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 77/272 (28%), Positives = 118/272 (43%), Gaps = 18/272 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q       + N  +   ++ +AA+  A L  LPE   A    D      +    
Sbjct: 5   MNLAVIQMVSQDDVQSNLRLARRMLERAAQGGARLVVLPENFAAMGRRDLTAIGHAEAAG 64

Query: 61  EGEFLGRLRRESKRNMMTTILTI----HVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD 115
           EG  L  L++ ++   +  +             GR     + +   G  VARY KLHL+D
Sbjct: 65  EGPILPWLKQAARDLSLWIVAGTLPLPPDDEPQGRPHACSLLIDEQGERVARYDKLHLFD 124

Query: 116 A------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
                     +ES     G  +  + +    ++GL  CYDLRFPEL  A    GAE++ +
Sbjct: 125 VDVTDNRGRYRESDDFVHGQRLV-VADTPVGRLGLTVCYDLRFPELFGALREAGAELISV 183

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAA 224
           PAA+        HW  L  ARA++T CY++AAG+ G         G S IIDP+G  +  
Sbjct: 184 PAAFTA-VTGAAHWQVLTRARAIETQCYILAAGQGGEHPGQRLTFGHSAIIDPWGTVLVE 242

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             +    ++A         +R ++PV  +RRF
Sbjct: 243 QDQGEGALLAARDAAEQAAIRQRMPVQQHRRF 274


>UniRef50_A4S5E0 Predicted protein n=2 Tax=Ostreococcus RepID=A4S5E0_OSTLU
          Length = 282

 Score =  242 bits (618), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 73/276 (26%), Positives = 121/276 (43%), Gaps = 28/276 (10%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            +A  Q   T+ ++ N +    L  +A         LPEA       DA      A+ L+
Sbjct: 7   RIACAQMTSTADFQHNLQTVTELCKRAKAEACEALFLPEAFARIGATDASY----AEPLD 62

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA--GNIVA-RYAKLHLYD- 115
           G  +      +K   +   L  +        + +N  V +    G I    Y K+HL+D 
Sbjct: 63  GPIVRACCALAKEYGLWMSLGGYAERDGDGRKRFNSHVMIDPRSGEISGDVYRKIHLFDT 122

Query: 116 -------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQG-AEIL 167
                     ++ES    AG  +A   +    KVG   CYDLRFP++  A   +  A+++
Sbjct: 123 DAAVGVDGGGMRESDYTRAGTTLAS-YDTTFGKVGASICYDLRFPDVYQALRFEHEADVI 181

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTI 222
            +P+A+ +    + HW  LL ARA++T CY+VAA + G         G + +IDP+G  +
Sbjct: 182 CVPSAFTKST-GQAHWEVLLRARAIETQCYVVAAAQAGKHGETRESYGHAMVIDPWGRIV 240

Query: 223 AAASE---MPALIMAEVTPERVRQVRAQLPVLNNRR 255
           A   +      + +AE+    V  +R Q+P+  +RR
Sbjct: 241 AKMDDPSNEVGIAVAEIDLALVDSIRTQMPLAEHRR 276


>UniRef50_Q9KE11 BH1047 protein n=2 Tax=Bacillaceae RepID=Q9KE11_BACHD
          Length = 271

 Score =  241 bits (617), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 69/269 (25%), Positives = 119/269 (44%), Gaps = 15/269 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAEND--ASLFALPEALLARDDHDADLSVKSA 57
           M VA  Q  +       N       +    + +    L  LPE       +  D     A
Sbjct: 1   MKVALYQMDILPGDPRGNERKVKEWIEDVMQQEDVPDLLVLPEMWTTA--YTLDQLEHLA 58

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYDA 116
           +  E      L+  ++ + +  +         G+ +N   V  + G+ V +Y K+HL   
Sbjct: 59  EGEERYTELFLKELAREHNVNIVAGSIAKKEKGKLYNRALVFDRRGHTVYQYDKIHLVPM 118

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
            +  E   +  G+  A + E+EG K+GL+ CYDLRFPEL  + AL+GAEI+ + A W   
Sbjct: 119 LS--EPDYLTGGDAAASVFELEGTKMGLVICYDLRFPELMRSLALEGAEIVFIVAEWPEA 176

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAAS-EMPAL 231
             +  HW  L  ARA++   Y+++    G        G+S +IDP+G  +   S +    
Sbjct: 177 --RAVHWEVLQRARAIENQSYVISCNRVGAYAGVTFAGRSMVIDPWGDVLIQGSRDQEQT 234

Query: 232 IMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           +  ++ P++V +VR  +P+  +R     +
Sbjct: 235 LTTKLNPDKVSEVREAVPIFQSRVPTKYK 263


>UniRef50_A5VIE2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=10 Tax=Lactobacillales RepID=A5VIE2_LACRD
          Length = 261

 Score =  241 bits (617), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 64/265 (24%), Positives = 109/265 (41%), Gaps = 13/265 (4%)

Query: 2   LVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            VA  Q  +      +N +     + +AA + A +  LPE       +  D   + A   
Sbjct: 4   KVALAQLDIQLGNPAENYQKAKQAIEEAANHHADIVVLPEMWNIG--YALDQLAELADEN 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
             +        + +N +  +            +N        GN+++ Y K+HL+    +
Sbjct: 62  GQKTQQFFSELALKNQINIVGGSVAVRNGQSFFNTTYVYDQNGNLISSYEKVHLFGL--M 119

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E + ++AG +     ++ G+      CYDLRFPE     A  G +IL  PA W     +
Sbjct: 120 NEDQYLEAGQK-ENHFKLAGIPSASFICYDLRFPEWIRTVARYGTDILYFPAEWPSK--R 176

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAE 235
              W  +L +RA++   ++VA    G        G S +IDP G  I  A E+  +  AE
Sbjct: 177 IEQWKIMLRSRAIENQAFVVAVNRVGTDLENSFNGHSLVIDPLGQVIHDAGEVEQVSYAE 236

Query: 236 VTPERVRQVRAQLPVLNNRRFAPPQ 260
           +   ++ QVR  +PV  +RR +   
Sbjct: 237 IDLAQLAQVRGPIPVFKDRRPSLYH 261


>UniRef50_Q11M91 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Chelativorans sp. BNC1 RepID=Q11M91_MESSB
          Length = 272

 Score =  241 bits (615), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 81/269 (30%), Positives = 124/269 (46%), Gaps = 17/269 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAEND-ASLFALPEALLARDDHDADLSVKSAQLL 60
            +   Q         N     SL+  A E D +     PE       + A +   +  L 
Sbjct: 3   KITVVQINTRDDKAANLAKLESLVRAAHEADHSDYILTPEHSFCLTANKATMHAAAETLE 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLH-----LY 114
           +GE L R+   ++    T  +   + +  GR +N  V +   G  +A Y K+H     L 
Sbjct: 63  DGEGLRRMASLARELGTTIHIGSILTTRNGRYYNTSVVIGPDGKQLATYDKIHRYDVDLP 122

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              + +ES   DAGN +A   +  G  VGL  CYD+RF  L L  A +GA+++ +PAA+ 
Sbjct: 123 SGLSYRESDTNDAGN-VAVTYDHNGTNVGLSVCYDVRFGSLYLELAARGAQVITIPAAFT 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECG--------NKNIGQSRIIDPFGVTIAAAS 226
                  HW TL+ ARA++T CY+ AAG+ G          + G S+I+DP+G  +A  S
Sbjct: 182 FET-GAAHWDTLVRARAIETQCYVAAAGQVGSFPASGGDRASFGNSQIVDPWGKVLARCS 240

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           ++     A + P    +VR  LPV  +RR
Sbjct: 241 DVEGWASAAIDPSYQNRVRQNLPVARHRR 269


>UniRef50_D1VY57 Hydrolase, carbon-nitrogen family n=1 Tax=Prevotella timonensis
           CRIS 5C-B1 RepID=D1VY57_9BACT
          Length = 318

 Score =  240 bits (614), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 55/283 (19%), Positives = 107/283 (37%), Gaps = 23/283 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADL--SVKSAQ 58
           + +   Q   T   + N +  A  +   A+  A L  L E   +      +   +   A+
Sbjct: 27  IRIGILQLRNTECVDDNKKKIAENITDLAQRGAQLIVLQELHNSLYFCQVEDVNNFDLAE 86

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
            + G       + +++  +  + ++     PG   N  V ++  G I  +Y K+H+ D  
Sbjct: 87  PIPGPSTEYYGKLAQQLGIVIVTSLFEKRAPGLYHNTAVVIEKDGTIAGKYRKMHIPDDP 146

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
           A  E      G+     ++    ++G++ C+D  +PE A   ALQGA++L+ P A     
Sbjct: 147 AYYEKFYFTPGDLGFHPIDTSVGRLGVLVCWDQWYPEAARLMALQGAQLLIYPTAIGYES 206

Query: 178 LKEH--------HWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRIIDPF 218
             +          W+T+    A+     ++     G++             G S +  P 
Sbjct: 207 SDDEDEQQRQRNAWTTVQRGHAVANGLPVITVNRVGHEDDPSGQTNGIDFWGSSFVAGPQ 266

Query: 219 GVTIAAA-SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           G     A  +    ++ ++  +   QVR   P L +RR    Q
Sbjct: 267 GELYYQACDDDEESVVIDIDLDHSEQVRCWWPFLRDRRIENYQ 309


>UniRef50_A7I5W9 Porphyromonas-type peptidyl-arginine deiminase n=4
           Tax=Methanomicrobia RepID=A7I5W9_METB6
          Length = 640

 Score =  240 bits (614), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 65/272 (23%), Positives = 101/272 (37%), Gaps = 15/272 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARD--DHDADLSVKSAQL 59
            +A  Q  +    ++N       + +AA+N A    LPE    R             A+ 
Sbjct: 7   TIALIQMEIGPDPDRNLNEARERVEKAAQNGAQFICLPELFRTRYFPQQIGTPVQSLAET 66

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
           + GE      R +K      I+ +   S  G   N  V +   G++ A Y K+H+     
Sbjct: 67  IPGESTDVFTRIAKEYKAVIIVPVFERSPLGHLENAAVVIDADGSLHAPYYKVHIPQDPK 126

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA----WV 174
             E      GN  A +      K+ ++ CYD  FPE A   +L+GAEI+  P A      
Sbjct: 127 FFEKGYFYPGNHYA-VHATRYGKIAVLICYDQWFPEAARCVSLEGAEIIFYPTAIGNPCT 185

Query: 175 RGPLK---EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASE 227
             P +   +  W  +  + A+  + ++ A    G +      G S I D FG  +A A +
Sbjct: 186 EQPSEGDWQEAWEIIQRSHAIANSVHIAAVNRAGGEGNIRFFGGSFICDAFGKVLARAGD 245

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
               I A    E    +R       NRR    
Sbjct: 246 ANETITATADLELNESIRDSWGFFRNRRPDTY 277


>UniRef50_C7NXL9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Halobacteriaceae RepID=C7NXL9_HALMD
          Length = 270

 Score =  240 bits (613), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 84/273 (30%), Positives = 130/273 (47%), Gaps = 23/273 (8%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q  V     E N E   +++ +AA+    L ALPE          D   ++A+ 
Sbjct: 1   MKIALAQHRVEAGTVEANVERATAMIERAADRGVGLVALPELFATGY-FAFDAYARTAES 59

Query: 60  LEGEFLGRLRRESKRNMMTTILT-------------IHVPSTPGRAWNMLVALQAGNIVA 106
           L G  L RLR  +    +  +               I  P+T G A   ++    G   +
Sbjct: 60  LTGPTLTRLRETAAEQDLALLAGSIVEDLAASHAAGIETPATEGYANTSVLFDSDGRRRS 119

Query: 107 RYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI 166
            Y K HL+  +   E   ++ G  I    ++ G  VG+ TCYDLRFPEL    A +G  +
Sbjct: 120 VYRKHHLF-GYGSAEQDLLEPGERI-QTADIGGFTVGVTTCYDLRFPELYRELADRGVTL 177

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTI 222
           +++P+AW     +  HWS L  ARA++   Y+ AA   G  +    +G+S + DP+G  I
Sbjct: 178 VLVPSAWPYP--RVEHWSVLPKARAVENLTYVAAANGVGTFDGEALLGRSTVYDPWGTPI 235

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           A+  + PAL+ A++ P+RV  VR   P L++RR
Sbjct: 236 ASTGDEPALVTADLDPDRVAAVRESFPALDDRR 268


>UniRef50_D0RND5 Hydrolase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RND5_9RICK
          Length = 265

 Score =  240 bits (613), Expect = 4e-62,   Method: Composition-based stats.
 Identities = 68/262 (25%), Positives = 123/262 (46%), Gaps = 15/262 (5%)

Query: 1   ML--VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M    A  Q       ++N +    L  QA ++ A +   PE        +  L  KS  
Sbjct: 1   MKFNAACLQLTSNDQPKENLDQVIKLSDQAVKDGAQIILTPENTFLLTLDEGVLKEKSED 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-- 115
             +G  +  + + +K N +  ++           +N  V +   G IV  Y K+H++D  
Sbjct: 61  YEKGFCINEIVKYAKSNSIWFLIGGTPVKENNNIFNRSVLISPKGEIVTTYDKIHMFDVN 120

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                + +ES++  AG  ++ + ++    +GL  CYDLRFP        +GA+ L +P+A
Sbjct: 121 LPNGESYEESKKFKAGESLS-VTKLPWGNLGLSICYDLRFPNHYRQLMKKGADFLAVPSA 179

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW  LL +RA++  CY++A  + G         G S I+ P GV ++   E
Sbjct: 180 FTKNT-GERHWHILLRSRAIENFCYVLAPAQTGKHFNNRETYGHSMIVSPDGVVLSEKKE 238

Query: 228 MPALIMAEVTPERVRQVRAQLP 249
              LI++E+  E+V+++R+++P
Sbjct: 239 DIGLIISEIDIEKVKKIRSEIP 260


>UniRef50_Q5DC61 SJCHGC06938 protein n=1 Tax=Schistosoma japonicum
           RepID=Q5DC61_SCHJA
          Length = 290

 Score =  240 bits (612), Expect = 4e-62,   Method: Composition-based stats.
 Identities = 75/282 (26%), Positives = 122/282 (43%), Gaps = 26/282 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  V +    N +  + L+++A  E+ A L  LPE         A      A+ 
Sbjct: 2   LRLALVQMFVGTDKAANLKRASDLISRAVSEHSAQLVCLPECF--TSPIGAKYFEPYAEP 59

Query: 60  LE-GEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLV-ALQAGNIVARYAKLHLYDA 116
           +  G     L   +K + +  +   I    + G+ +N        G +V  Y KLHL+D 
Sbjct: 60  VPNGPACQMLSNAAKSHKIWLVGGSISERGSDGKIYNCCATYNPDGELVGLYRKLHLFDI 119

Query: 117 -----FAIQESRRVDAGNEIAPLL--------EVEGMKVGLMTCYDLRFPELALAQALQ- 162
                F  +ES  + +G E             ++  ++VG+  CYD+RFPEL+L  A Q 
Sbjct: 120 DIPGQFTFKESASLSSGKETFSFEMPLKSSENKISVIRVGIGICYDIRFPELSLLYANQL 179

Query: 163 GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDP 217
           G ++L+ PAA+        HW  L  ARALDT CY+       N      +  +S I  P
Sbjct: 180 GCQLLLFPAAF-NPKTGSLHWELLGRARALDTQCYVGMCSPACNLELDYISYAESLITSP 238

Query: 218 FGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +G+ IA   +   ++ A +    ++ VR  +P+   RR    
Sbjct: 239 WGMVIAKGGKEEEILTANLDFSELKHVRESIPIGRQRRLDIY 280


>UniRef50_UPI0000E7FA0A PREDICTED: hypothetical protein isoform 1 n=1 Tax=Gallus gallus
           RepID=UPI0000E7FA0A
          Length = 250

 Score =  240 bits (612), Expect = 4e-62,   Method: Composition-based stats.
 Identities = 55/272 (20%), Positives = 109/272 (40%), Gaps = 40/272 (14%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +A  Q  V++V   N +    L+ +A+   A + ALPE       +      + A+ +
Sbjct: 4   FRLALIQLHVSAVKSDNLQRACGLIREASAKGAKVVALPECF--NSPYGTQYFKEYAEKI 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYD---- 115
            GE   +L   +K   +  +         G+ +N   V    G I+A++ K+HL+D    
Sbjct: 62  PGESTQKLSAVAKECSIYLVGGSIPEEDGGKLYNTCTVFGPDGAILAKHRKIHLFDINVP 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ES  +  G+                + +D R             ++L+ P A+ 
Sbjct: 122 GKIQFKESETLSPGDS--------------FSMFDTR------------CQLLIYPGAFN 155

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  L   RA+D   Y+       ++       G S +++P+G  IA A    
Sbjct: 156 M-TTGPAHWELLQRGRAVDNQVYVATVSPARDEKASYVAWGHSTVVNPWGEVIAKAGAEE 214

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            +I  ++  +++ ++R Q+P+L+ +R+    +
Sbjct: 215 TVIYTDIDLKKLAEIRQQIPILSQKRYDLYGI 246


>UniRef50_A0LQU6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Acidothermus cellulolyticus 11B
           RepID=A0LQU6_ACIC1
          Length = 272

 Score =  240 bits (612), Expect = 5e-62,   Method: Composition-based stats.
 Identities = 80/273 (29%), Positives = 123/273 (45%), Gaps = 24/273 (8%)

Query: 1   MLVAAGQFAVTSV--WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M +   Q  V+    W    +    L+  A+  DA L  LPE  +      +    + A 
Sbjct: 1   MRITILQLEVSDHEPWPDRVDRVVDLV--ASCRDADLVVLPELWVPG-AFASRFFAEVAT 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHV----PSTPGRAWNMLVALQA-GNIVARYAKLHL 113
            L G  + RL   +K      +    +    P+T    +N  V L   G I   Y K+HL
Sbjct: 58  ELPGPIIPRLGAVAKELGAFIMAGTFIERADPATDRIGYNTAVLLNPDGAIAHTYRKVHL 117

Query: 114 YDAFAIQESRRVDAGNEIAPLLEVEGMKV------GLMTCYDLRFPELALAQALQGAEIL 167
           +  F   E+R + AGN+      +EG ++      G  TCYDLRFPEL      QG ++L
Sbjct: 118 F-GFHEGEARMLAAGND-VTTCRLEGGRMTETATYGTSTCYDLRFPELYRILVDQGCDLL 175

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIA 223
           V+P+ W    L   HW  L  ARA++   ++VA  E G+    +  G S ++DP+G  +A
Sbjct: 176 VIPSGWPAQRL--EHWRVLTRARAIENQLFVVACNETGHQQGVELAGHSVVVDPWGQVVA 233

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            A     ++  ++    V ++R   PVL +RRF
Sbjct: 234 EAGAGEEILTVDIDLGEVPRIRRDFPVLPDRRF 266


>UniRef50_Q15ZG7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Alteromonadales RepID=Q15ZG7_PSEA6
          Length = 276

 Score =  240 bits (612), Expect = 5e-62,   Method: Composition-based stats.
 Identities = 76/270 (28%), Positives = 121/270 (44%), Gaps = 16/270 (5%)

Query: 5   AGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEF 64
           A Q   T    +N       +AQ   N+ +L  LPE        D  L   +  L +G  
Sbjct: 6   ALQMTSTPDVTENLHFVEQQLAQLTVNEPTLVVLPECFACFGGGDKALLSIAESLGDGPI 65

Query: 65  LGRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF---- 117
             RL   +K+  +  +          P +     + +   G  V  Y K+HL+D      
Sbjct: 66  QARLMGMAKQYGVWLVAGSMPLKSENPDKFTASCLLINDAGERVTEYQKIHLFDVQVADN 125

Query: 118 --AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA-EILVLPAAWV 174
                ES+   AG+ +  + +     +GL  CYD+RFP L  A A   A +++ LPAA+ 
Sbjct: 126 TKTYCESKYTQAGSTLVSVPDTPFGHLGLAICYDVRFPGLFQAMAEHKALDVIALPAAFT 185

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASEMP 229
           +    E HW  LL+ARA++  CY+VAAG+ G      +  G S II P+G T+A   +  
Sbjct: 186 Q-KTGEAHWQALLSARAIENQCYLVAAGQTGVHANQRQTHGHSCIISPWGETLAELPQSV 244

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            +I A++ P  + ++R  +PV  + +F   
Sbjct: 245 GVINAQLEPAILNRIRRDMPVYAHNKFRSY 274


>UniRef50_Q1AWK1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Bacteria RepID=Q1AWK1_RUBXD
          Length = 276

 Score =  239 bits (611), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 78/269 (28%), Positives = 127/269 (47%), Gaps = 16/269 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
            AA Q + T    +N  +  +L+ +AA   A+L ALPE          ++  ++A+ + G
Sbjct: 8   AAAIQMSSTPDRGENRRVAEALIREAAAAGATLVALPELWSCHG--LEEVYRENAEPIPG 65

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNML-VALQAGNIVARYAKLHLYDAFA- 118
                L   ++   +  +    +    G  R  N   +    G++VA Y K+HL+D    
Sbjct: 66  PTTEFLGSLARELGIYLLGGSILERVSGSERLGNTSTLYAPDGSLVAVYRKVHLFDVEVS 125

Query: 119 ---IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
                ES  +  G E     +   + VGL  CYD+RFPEL    AL+GAE+L +PAA+  
Sbjct: 126 GRRYLESANIAPGGEAVA-AKAGPVTVGLSVCYDVRFPELYRLLALRGAEVLAVPAAFTL 184

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPA 230
              K+ HW  LL ARA++   Y++A  + G K       G+S I+DP+G  ++   +   
Sbjct: 185 QTGKD-HWELLLRARAVENQAYVLAPAQWGRKADGRWTYGRSMIVDPWGTVLSTCPDRDG 243

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             +A +    + ++RA+ P L NRR    
Sbjct: 244 YALATLDLGYLERLRAEFPSLANRRPRVY 272


>UniRef50_C8S929 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Archaeoglobaceae RepID=C8S929_FERPL
          Length = 250

 Score =  239 bits (611), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 76/255 (29%), Positives = 129/255 (50%), Gaps = 12/255 (4%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M+VA  Q  +    E N     SL+ +A +++A +  LPEA       +    V+S +  
Sbjct: 1   MIVAVAQQRIVEDVEVNKMKALSLVKRAIQHEAKIVVLPEASNTGLFPENFGKVRSLE-- 58

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
             E L  + + S+R  +  I  + V  + G  +N +  +  G ++ +Y+K+ L+     +
Sbjct: 59  --EELDLILKLSERKDILVIAGV-VERSEGNLFNSVALIYRGEVIGKYSKILLFPLN--E 113

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           E + + AG E+  + E +  K+G++ CY++RFPE+A      GAEIL +PA +     + 
Sbjct: 114 ERKYLTAGKEL-KVFETDFGKIGVLVCYEVRFPEMARKLMKMGAEILAVPAEFPAE--RI 170

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNI--GQSRIIDPFGVTIAAASEMPALIMAEVTP 238
            HW TLL ARA++   Y++ A          G S I+DP G  +  A  +  +I+ EV  
Sbjct: 171 EHWRTLLRARAIENQFYVLGANCVSPDGFYGGNSMIVDPMGNVVNEAGNLQEIIIGEVNL 230

Query: 239 ERVRQVRAQLPVLNN 253
           E VR+VR + P L +
Sbjct: 231 EYVRRVREEYPFLKD 245


>UniRef50_Q9Y9L1 Putative hydrolase n=1 Tax=Aeropyrum pernix RepID=Q9Y9L1_AERPE
          Length = 268

 Score =  239 bits (610), Expect = 9e-62,   Method: Composition-based stats.
 Identities = 82/265 (30%), Positives = 127/265 (47%), Gaps = 4/265 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEAL-LARDDHDADLSVKSAQL 59
           M +A  Q A T   + N E    L ++  +N   +   PE L L       D    +A+ 
Sbjct: 1   MNIAVLQVASTREKDANLESVKRLASR-VKNSPDIVLTPEYLMLDPTGLGRDAIYDAAED 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFA 118
           LEG +   L + ++      +  + + +  GR  N  V   + G I+  Y K HL+DA+ 
Sbjct: 60  LEGRWSRELSKIAESLGSCLLGHLFLKTPSGRVANAAVLYSRDGGIIGVYRKTHLFDAYG 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL-QGAEILVLPAAWVRGP 177
             ES   + G+E+    +  G  +G+  CY+LRFPE+   Q+L  G +I ++PAAW RGP
Sbjct: 120 YVESSFTEPGDELWEPRKACGASIGVAICYELRFPEIFRTQSLVGGVDIFLVPAAWYRGP 179

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVT 237
            KE   S L  ARA + T Y+  A   G   +G+S II P G T+A A     ++  E+ 
Sbjct: 180 GKEEALSVLSRARAQENTSYVAVASNAGANFVGRSMIIHPLGYTLAQAPPWEWVLEHEID 239

Query: 238 PERVRQVRAQLPVLNNRRFAPPQLL 262
              + + R  LPVL + +    + L
Sbjct: 240 LREIERARKSLPVLEHVKPHLYRYL 264


>UniRef50_B4RQA3 Nitrilase n=28 Tax=Neisseriaceae RepID=B4RQA3_NEIG2
          Length = 281

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 80/266 (30%), Positives = 116/266 (43%), Gaps = 16/266 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q       E N      L+A+AAE  A    LPE  +    +D      +  L 
Sbjct: 15  IRVAAVQMVSGVSPETNVAAMKRLVARAAEQGADWVLLPEYWVLMGANDTGKLALAEPLG 74

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
            G F   L   +K   +          +P  G+  N L+     G     Y K+HL+   
Sbjct: 75  GGRFQTALSETAKECGVVLFGGTVPLQSPEAGKVMNTLLVYGCDGVRTGLYHKMHLFGFS 134

Query: 118 A----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                  E+  + AG E  P L  EGM V    CYD+RFPE          ++L+LPAA+
Sbjct: 135 GLGERYAEADTIRAGRE-VPHLSAEGMPVAAGICYDVRFPEFFR--RQLPFDVLMLPAAF 191

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAASEM 228
                 + HW  LL ARA++  CY+VAA +      G +  G S I+DP+G  +    E 
Sbjct: 192 TH-TTGKAHWELLLRARAVENQCYVVAAAQGGLHENGRRTFGHSMIVDPWGDVLDVLPEG 250

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNR 254
             ++ A++   R+  VR +LP L +R
Sbjct: 251 EGIVTADIDANRLNSVRNRLPALKHR 276


>UniRef50_A3WPW5 Predicted amidohydrolase, nitrilase family protien n=2
           Tax=Idiomarina RepID=A3WPW5_9GAMM
          Length = 279

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 76/268 (28%), Positives = 123/268 (45%), Gaps = 14/268 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           L++A Q +      +N  +   L+ Q  E    L  +PEA       D      +  +  
Sbjct: 5   LLSAIQLSSFKTPTENLALLERLLEQLPEQRPQLVVVPEAFSCFGAGDRAQLDMAEPVGN 64

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWN-MLVALQAGNIVARYAKLHLYDAFA-- 118
           G    RL   +K++ +  +          R     L     G  +ARY K+HL+D     
Sbjct: 65  GPVQQRLSELAKQHEIYLVGGTIPLQAGERFAAASLCYGPDGRCLARYDKIHLFDVDVAD 124

Query: 119 ----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ESR   AG+ I  + ++    VG+  CYDLRFPEL  A   +GA+I++LP+A+ 
Sbjct: 125 NTRQYRESRWTRAGSSIVTI-DLGFAVVGMAVCYDLRFPELFKALRAKGADIILLPSAFT 183

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASEMP 229
                  HW  L+ ARA++   YM+A  + G      +  G S I+DP+G  +A  ++  
Sbjct: 184 E-VTGAAHWHPLVRARAIEQQVYMLAPNQYGEAANGRRTYGHSMIVDPWGEVVAEQADGE 242

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFA 257
            ++ A    E++  +RAQ+PV +  R A
Sbjct: 243 GVVSAYFDREKLENIRAQMPVADQTRLA 270


>UniRef50_Q0S9Y1 Possible nitrilase n=3 Tax=Actinomycetales RepID=Q0S9Y1_RHOSR
          Length = 270

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 14/262 (5%)

Query: 1   MLVAAGQFAVTSV--WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M +A  Q A           E   +L+   AE    L  LPE      +H  D    +A+
Sbjct: 1   MKIALAQLASPDSETPAHRLERVRNLLTGLAER-VDLIVLPELWRVGYNH-FDDYSTAAE 58

Query: 59  LLEGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA 116
            L G  +  L   +           I      GR  N  V +   G I   Y+K+H++  
Sbjct: 59  TLGGGTVQVLAAVAVERQCYIHAGSIVEQGEEGRLRNTAVLIGPDGQIHHHYSKVHVFGY 118

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
            ++ E++ +  G +I    +     +   TCYDLRFP L       GA+++++PAAW + 
Sbjct: 119 DSL-EAQLLQPGTQIHTT-DTPFGPIAATTCYDLRFPGLWTELVAAGAQLVIVPAAWPKA 176

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALI 232
             ++ HW  L +ARA+D   +++A    G  N     G SRI+DP+G  IA A     + 
Sbjct: 177 --RKEHWRLLTSARAVDNQVFVIACNATGTHNSVELGGHSRIVDPWGTVIAEADSSEGIT 234

Query: 233 MAEVTPERVRQVRAQLPVLNNR 254
           +AE+ P  V + RA+ PVL +R
Sbjct: 235 IAEIDPAVVDRTRAEFPVLRDR 256


>UniRef50_C1AA71 N-carbamoylputrescine amidohydrolase n=12 Tax=Bacteria
           RepID=C1AA71_GEMAT
          Length = 307

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 57/292 (19%), Positives = 101/292 (34%), Gaps = 33/292 (11%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
           + +   Q   +     N     + +  AA + A +  L E   A              A+
Sbjct: 5   VTIGIVQDTASDDLASNVTRAVARVRDAASSGAQIICLQELFNAPYFCKTVRPERFDIAE 64

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
            ++G  +   +  +K   +  ++  +    PG   N    +   G I+  Y K+H+    
Sbjct: 65  PVDGPIVHTFQALAKELAVVIVVPFYEREAPGLYRNSATVIDADGAILGTYRKMHIPHDP 124

Query: 118 AIQESRRVDAGN-------------EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA 164
             +E      G+                 +   +   +G++ C+D  +PE A   +L GA
Sbjct: 125 LFEEKYYFAPGDVTGDQRTDRHPGYNGFRVWRTKYADIGVLICWDQWYPEGARITSLLGA 184

Query: 165 EILVLPAAW--------VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK--------- 207
           +IL  P A           G  +   W T   A A+    ++ +    G +         
Sbjct: 185 QILFYPTAIGWHPAEKPTFGDAQVDAWRTAQRAHAIANGVFVASPNRVGFEPEPGTEGLE 244

Query: 208 NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             GQS I DPFG  +A A   P ++ A      + + R   P L +RR    
Sbjct: 245 FFGQSFICDPFGRYLAQAGTEPTILTATCDLGLIEETRRNWPFLRDRRIDAY 296


>UniRef50_A1SU00 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Psychromonas ingrahamii 37 RepID=A1SU00_PSYIN
          Length = 274

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 76/268 (28%), Positives = 121/268 (45%), Gaps = 16/268 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           ++A Q    S+  +N      L+A  +     L  LPE  L   D D  L++ S  L +G
Sbjct: 5   LSAIQMHSLSLPSENLARLRVLLAALSPIPGQLVLLPENALCIADKDHYLAL-SENLGKG 63

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQA-GNIVARYAKLHLYDA--- 116
            +   L   +K      I       +    + +   +     G +++ Y K+HL+DA   
Sbjct: 64  YYQSLLSALAKHYQCYLICGSFPIKSTITDKIFTTCLVFSPLGELISHYHKMHLFDAQVA 123

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGM----KVGLMTCYDLRFPELALAQALQGAEILVL 169
                 +ES     G E   L   +      KVGL  CYDLRFP L      QGA+IL++
Sbjct: 124 DHKGIYKESDTFVPGQE-VKLFNWDCGAYSVKVGLTICYDLRFPGLFQTLRKQGADILLV 182

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMP 229
           PAA+ +    + HW  LL ARA++  CY++AA +  ++  G S II P+G  +   +E  
Sbjct: 183 PAAFTQ-TTGQAHWLPLLQARAIENQCYIIAANQSSHETYGHSMIISPWGEVLEQLAEGE 241

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFA 257
             I       ++ ++R  +P+L + RF 
Sbjct: 242 GSIHHLFEKSQIEKIRQAMPILEHNRFT 269


>UniRef50_C7N2Y0 Predicted amidohydrolase n=1 Tax=Slackia heliotrinireducens DSM
           20476 RepID=C7N2Y0_SLAHD
          Length = 270

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 72/267 (26%), Positives = 126/267 (47%), Gaps = 9/267 (3%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A  Q +                 +AA   A L   PE  +     D++   + ++ L
Sbjct: 3   LTIALAQ-SGFPKKGDAIAQAERYAEKAAAAGAQLLVFPENFMLPGILDSEGVKEISEPL 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVALQAGNI-VARYAKLHLYDAFA 118
           +G F   +   + R+ +  +  I   +  G + +N  V + A  +    Y K HLYDA  
Sbjct: 62  DGPFARAMADIALRHHLWIVYVIFEENPDGGQPFNTAVTVDAEGVQRGAYRKCHLYDAHG 121

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + ES R  AG+++   ++     +G+  CYDLRFPE+A A A+ G ++++ P+AW  GP 
Sbjct: 122 VLESDRSVAGDQLPQPVDTPFGPLGVAICYDLRFPEVARALAVAGCKLVLFPSAWNAGPR 181

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEM------PALI 232
           K  HW+TLL ARA++   ++      G +  G++ + DP G  +A+A           L+
Sbjct: 182 KVKHWTTLLRARAIENELFVAGICHAGKRYTGKTLVADPLGRIVASARGSSKGNAPQDLV 241

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +  +  + V   R  +PVL++RR    
Sbjct: 242 ICTIDTDAVESARDAMPVLDHRRPELY 268


>UniRef50_C6JLR5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Fusobacterium varium ATCC 27725
           RepID=C6JLR5_FUSVA
          Length = 274

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 67/258 (25%), Positives = 117/258 (45%), Gaps = 15/258 (5%)

Query: 13  VWEKNAEICASLMAQAAENDA--SLFALPEALLARDDHDADLSVKS-AQLLEGEFLGRLR 69
             E N +   +L  +A +      +  LPE             +++  +   G  +  L+
Sbjct: 15  DAEYNFKNVKNLFKEAMKYKPTPDVVVLPEDWSYGFSDKMFHDMENYCEAENGPSVSILK 74

Query: 70  RESKRNMMTTILTIHV--PSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAIQESRRVD 126
             +K   +  +        S  G+  N    + + G I+A Y+K+HLY    + E+  ++
Sbjct: 75  ELAKEYKVFVVAGSIATKSSKDGKIRNTTFLINRNGEIIADYSKMHLYSD--MDENFMIE 132

Query: 127 AGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTL 186
           +GN+ A ++E E  K G M CYD+RF EL+   AL+GAE +++ + +     + +HW TL
Sbjct: 133 SGNK-AEVVETEIGKFGFMICYDIRFCELSRIYALKGAEAIIVTSDFPNP--RVNHWRTL 189

Query: 187 LAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVR 242
           L ARA++   +++A    G        G S IIDP+G  IA   E   +I   V    + 
Sbjct: 190 LQARAIENQMFVIACNRVGESPMGSYCGHSLIIDPWGEIIAEGGEKEEIIHGSVDLSVIH 249

Query: 243 QVRAQLPVLNNRRFAPPQ 260
            +R  + V  +R     +
Sbjct: 250 NIRETIHVFRDRHPEFYE 267


>UniRef50_Q724C2 Hydrolase, carbon-nitrogen family n=20 Tax=Bacilli
           RepID=Q724C2_LISMF
          Length = 259

 Score =  237 bits (606), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 68/264 (25%), Positives = 112/264 (42%), Gaps = 13/264 (4%)

Query: 2   LVAAGQFAVTSV-WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            +A  Q  V     + N       + +AA+N A +  LPE       +  +     A L 
Sbjct: 3   KLALCQTDVVFKYPDANYARIEKAIVEAAKNGADIAVLPEMWNTG--YALNELAGVADLN 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAI 119
                  L   S+++ +  I      S   +  N + A    G +++ Y K+HL+    +
Sbjct: 61  GERTKEFLATLSEKHQIAIIGGSVSISEGTKFSNTMYAFDKYGGLLSSYKKVHLFQL--M 118

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E   ++AGN+   L  ++G+      CYD+RFPE       +G+E++ + A W     +
Sbjct: 119 NEHLYLEAGND-TNLFRLDGVSCAGFICYDIRFPEWIRKHTSEGSEVIFVSAQWPAE--R 175

Query: 180 EHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAE 235
              W  LL ARA++   ++VA    G    N   G S +IDP G  +A   E    I AE
Sbjct: 176 VTQWEQLLIARAIENQAFVVAVNRVGDDPNNHFNGHSLVIDPLGNIVAHGGEDEGNIYAE 235

Query: 236 VTPERVRQVRAQLPVLNNRRFAPP 259
           +  + V + R  +PV  +RR    
Sbjct: 236 IDLKLVAETRGIIPVFTDRRPELY 259


>UniRef50_Q5WM18 Methylthioribose recycling protein n=3 Tax=Bacillales
           RepID=Q5WM18_BACSK
          Length = 275

 Score =  237 bits (606), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 122/269 (45%), Gaps = 16/269 (5%)

Query: 1   MLVAAGQFAVTSVW-EKNAEICASLMAQAAENDAS---LFALPEALLARDDHDADLSVKS 56
           M VA  Q  V +   ++N E   + + Q             LPE       +  +   + 
Sbjct: 12  MHVAVFQMEVLAGKPDENRERVKTWVEQLCREQLERPLTIVLPELWTTG--YQLEDLGEL 69

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD 115
           A+    E +  L++ ++ + +  +         G  +N  + + A G +V  Y K+HL  
Sbjct: 70  AEEEGVETIAFLQQLARAHRIHMVAGSIATKKDGGIYNTALVIDAQGKLVYTYDKVHL-- 127

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
              + E   +  G+    L E++G+K+ ++ CYDLRFPELA   AL+GAE+L + A W  
Sbjct: 128 VPMLNEPAYMQGGSVPPALFELDGVKMAVLICYDLRFPELARRLALEGAEVLFIVAEWPL 187

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAA-ASEMPA 230
              +  HW  L  ARA++   Y+++    G+       G S +IDP+G  I   +S    
Sbjct: 188 A--RAMHWKALQQARAIENQFYLLSCNSVGSHNGTDYAGTSMVIDPWGEIIVEGSSTEEE 245

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            +  +V   +  +VR ++PV ++RR    
Sbjct: 246 WLQCKVDFSKAAEVRDRVPVFSSRRPDLY 274


>UniRef50_C6B8T0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM1325
           RepID=C6B8T0_RHILS
          Length = 287

 Score =  237 bits (606), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 75/271 (27%), Positives = 116/271 (42%), Gaps = 19/271 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q +       N    A LM +A      L  LPE         AD    + ++ 
Sbjct: 1   MKIALVQMSSQPDRAYNLAEAARLMREAMIGRPDLIVLPEHFDWLGGTVADKRRAADRIP 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPST--PGRAWNMLVALQ-AGNIVARYAKLHLY--- 114
            GE    ++R +K N +       +       R +N  V     G  V  Y K+HL+   
Sbjct: 61  GGEAYVLVQRFAKDNAVWVHAGSLMERRGQDHRVYNTTVVFNAKGEEVGLYRKIHLFDIT 120

Query: 115 --DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
             D     ES  V  G ++  + E++G ++G   CYDLRF  L    A +  +I VLPAA
Sbjct: 121 APDGKTYSESAAVAPGRDLF-IYELDGHRIGCAICYDLRFSRLFDRLAEEKVDIFVLPAA 179

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECG---------NKNIGQSRIIDPFGVTIA 223
           +      + HW  L  ARA++   Y  A G+CG          +  G S + DP+G  +A
Sbjct: 180 FTYQT-GQAHWEVLCRARAIEFQAYFAACGQCGSYAMRDGELRRTFGHSMVCDPWGQIVA 238

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
            A     +++ E+ P R+ +VR  +P+  +R
Sbjct: 239 RAENDVCVLVVEIDPARLPEVRRLIPMAEHR 269


>UniRef50_B8C1M9 Nitrilase n=1 Tax=Thalassiosira pseudonana RepID=B8C1M9_THAPS
          Length = 320

 Score =  236 bits (604), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 70/300 (23%), Positives = 122/300 (40%), Gaps = 44/300 (14%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  QF VT    +N       + +A ++ A L  LPE       +        A++L 
Sbjct: 17  RVALLQFHVTHDKPQNINTAREYILKARDSGAQLCVLPEIW--NSPYATSAFGDYAEMLP 74

Query: 62  ------------GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARY 108
                       G     L   ++   M  +      +   + +N  + +   G IV ++
Sbjct: 75  SVGDTFSDKDKWGPSSQMLMELAQSTNMYIVGGSIPETCSDKIFNTCLVVNPKGTIVGKH 134

Query: 109 AKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEG-------MKVGLMTCYDLRFPELA 156
            K+HL+D         +ES  + AG E A   +V G        +VG+  CYD+RFPE A
Sbjct: 135 RKVHLFDVNVPGGIQFKESETLSAG-EGATYFDVAGEDGDSGMGRVGVGICYDIRFPEYA 193

Query: 157 LAQAL-QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-------- 207
           L        ++L+ P A+        HW  L  ARA+D  C+++ A    +         
Sbjct: 194 LLLTQIHKCKVLIYPGAFNL-TTGPAHWELLQRARAVDGQCFVLTASPARSNPPLDDEQT 252

Query: 208 ------NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
                   G S ++ P+G  +A   E PA+++A++   +V ++R  +P ++ +R    + 
Sbjct: 253 KHPHYSAWGHSTVVSPWGEVVATCDEHPAVVVADLDMSKVEEMRMAIPTMSQKRSDLYRF 312


>UniRef50_Q0VS65 Carbon-nitrogen hydrolase family protein n=2 Tax=Alcanivorax
           RepID=Q0VS65_ALCBS
          Length = 285

 Score =  236 bits (603), Expect = 6e-61,   Method: Composition-based stats.
 Identities = 82/274 (29%), Positives = 122/274 (44%), Gaps = 27/274 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q       + N E  A L+ +A +  ASL  LPE       +  D    +A+    
Sbjct: 10  VAAIQMTSVESAKANLEQAAQLLQEAHDQGASLAVLPENFA---GYGVDYRALAAEYERL 66

Query: 63  EFLGRLRRESKRNMMTTILTIH--------VPSTPGRAWN-MLVALQAGNIVARYAKLHL 113
           E    L  ++ R  M  I             P    R     L     G +V RY KLHL
Sbjct: 67  E--QWLCEQASRLGMAIIGGSIPSLTRPDGEPVPAPRVRTRSLAVSSEGQVVGRYDKLHL 124

Query: 114 YDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +DA         +ES   + G E      + G++VGL  CYDLRFP LA      GAE+L
Sbjct: 125 FDAQVHDAQGQYRESDFFEPG-EAIVTAPLGGVQVGLAICYDLRFPALAQRLTSAGAELL 183

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTI 222
           V P+A+     K  HW  LL A A+ T CY++ A +CG  +      G S ++ P+G  +
Sbjct: 184 VYPSAFTAVTGK-AHWELLLRATAVQTGCYVLGANQCGQHSPRRASYGHSMLVSPWGDVV 242

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           A+    P +++  +    + ++R ++PV  ++R 
Sbjct: 243 ASLGNAPGVLVTPLDLATLYELRQRMPVQQHQRL 276


>UniRef50_C0D6C3 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D6C3_9CLOT
          Length = 289

 Score =  236 bits (602), Expect = 7e-61,   Method: Composition-based stats.
 Identities = 67/261 (25%), Positives = 110/261 (42%), Gaps = 13/261 (4%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M+ A  Q         KN       + +AA+  A    LPE               +  +
Sbjct: 18  MIAAVIQMNCEPGNIRKNVAAARDFIRKAADKGAEWAVLPELFQTGYLLGGRDREYAGPV 77

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
             GE L  +   ++   +     I +    G+ ++  V +    ++  Y K+HL+     
Sbjct: 78  PGGEALCWMEETAREFGIMLTGGI-IEEQGGKLYDTAVTVSQHGLLGAYRKIHLWGG--- 133

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E  R   GN+    ++    K+G+  CY+  FPE A  Q L+GA  L   AA+  G  +
Sbjct: 134 -EKERFTPGNDTGTPMDCGNWKIGMQICYEAGFPEGARLQVLKGANALAYVAAF--GAAR 190

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPALIMA 234
              W     ARAL+  CY++A+  CG +       G+SRI+ P G  +A   E   + +A
Sbjct: 191 AEVWDLATRARALENGCYVLASDRCGTEPCGTKFAGRSRIVAPDGTILAQVEEGEGIAVA 250

Query: 235 EVTPERVRQVRAQLPVLNNRR 255
           ++    ++Q RA LP L + R
Sbjct: 251 KLELSNIQQQRAVLPYLKDLR 271


>UniRef50_C0VX65 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Corynebacterium glucuronolyticum
           RepID=C0VX65_9CORY
          Length = 257

 Score =  235 bits (600), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 75/258 (29%), Positives = 109/258 (42%), Gaps = 11/258 (4%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M VA  Q   +   + N  +    +  AA   A L   PEA        A     SA   
Sbjct: 1   MKVALCQINSSGDIDSNLALVEENVRTAAAEGARLIVFPEA--TMHAFGAGPLTGSAARF 58

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
            G F   ++       +  +     P    R +N  +  +       Y K HLYDAF   
Sbjct: 59  -GWFTTAIQSLVDDLSVAVVCGCFRPEEGERVYNTALIARPNEEPLLYDKTHLYDAFGFA 117

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES  V  G E     + EG+  G+  C+D+RFP L    A  GA+ +++P +W  G  K 
Sbjct: 118 ESDTVAPG-ENVVTFDWEGITFGVAICFDIRFPALFKKMARAGAQAIIVPTSWTPGEQKV 176

Query: 181 HHWSTLLAARALDTTCYMVAA-------GECGNKNIGQSRIIDPFGVTIAAASEMPALIM 233
           +HW  L  ARALD+  +++A        G      +G S +IDP G  +A   +   ++ 
Sbjct: 177 YHWRLLSRARALDSATFILATDQAFLDDGRTDPVGVGYSSVIDPLGQVVAELEQDEGILY 236

Query: 234 AEVTPERVRQVRAQLPVL 251
           AE+    V +VR  LPVL
Sbjct: 237 AELDTTAVEKVRQSLPVL 254


>UniRef50_D2VM50 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VM50_NAEGR
          Length = 300

 Score =  235 bits (600), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 73/297 (24%), Positives = 127/297 (42%), Gaps = 36/297 (12%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q    +    N  +C  L+ +A+E+ ASL   PE          +    S   L
Sbjct: 1   MKIALAQVRSINKIGFNFGVCEKLIKEASEHKASLICFPECFAFMGTSATETIANSGS-L 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPS---TPGRAWNMLVALQA-GNIVARYAKLHLYDA 116
           + E     +  +++  +      +       P + +N  + +   G I+  Y K+HL+D 
Sbjct: 60  DSELFKSYQDLARKYSINISYGGYHEKSSNDPHKIFNSHILVNNNGEIINVYRKVHLFDL 119

Query: 117 FA----IQESRRVDAGNEIAP----LLEVEGMKVGLMTCYDLRFPELALAQALQG-AEIL 167
                 ++ES   + G ++      L+    +K+GL  CYDLRFPEL +       A+IL
Sbjct: 120 NTEKVKLKESEITEFGKDLLVDDGGLIFSNDLKIGLSICYDLRFPELYILLRKMNNAKIL 179

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTI 222
           ++PAA+ +   +  HW TLL ARA++  CY++A+ + G  N      G S +IDP G  I
Sbjct: 180 LVPAAFTKHTGELGHWKTLLMARAIENQCYVIASAQVGTHNLKRQSYGHSLVIDPLGKII 239

Query: 223 AAASEMPALI---------------MAEVT--PERVRQVRAQLPVLNNRRFAPPQLL 262
                                      E+      +++VR  +PV +++R     ++
Sbjct: 240 LDLGSQEETFDLDIQEKEPFEGKLGFVEIDDWISNIKKVREGMPVFDHKRSDLYDVI 296


>UniRef50_Q46AW4 Putative amidohydrolase n=1 Tax=Methanosarcina barkeri str. Fusaro
           RepID=Q46AW4_METBF
          Length = 287

 Score =  235 bits (599), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 73/288 (25%), Positives = 117/288 (40%), Gaps = 37/288 (12%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q  V     ++N E    +  +A    A L  LPE       +  +    +A+ 
Sbjct: 1   MKVACIQMDVLHCRKQENLEKALHMALKAVRKGAELIVLPEVFSTGFCY--EHFDHAAET 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVP------STPG-----------------RAWNML 96
           L    L  L   S+ N    + ++         S  G                   +N+ 
Sbjct: 59  LPSPLLENLACFSEANDCIIMGSVIEKVALEETSDSGTPADSENSTLSNSSNSPFYYNLG 118

Query: 97  VALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLRFPEL 155
              ++G +   Y K H +      E+     G+ I P+ L+ + +K+G   CYDLRFPE+
Sbjct: 119 FCFESGTLAGSYRKTHPFKT----ENNYFSKGDSIEPISLKKQNLKIGFEICYDLRFPEV 174

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQ 211
           A   +L G+++LV  AA+     +  HW+ L  ARA++     +A    G+       G 
Sbjct: 175 ARKLSLAGSDLLVTTAAFPNP--RSEHWNILAKARAIENQIPHIACNRIGSAPDCSYFGN 232

Query: 212 SRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           S IID +G   A A     LI+ ++   R  +VR  +PV  N+R    
Sbjct: 233 SMIIDAWGEVKADAGNKECLIVHDLDLSRKNEVRKMIPVFENQRIELY 280


>UniRef50_B9JB81 Amidohydrolase protein n=4 Tax=cellular organisms
           RepID=B9JB81_AGRRK
          Length = 285

 Score =  235 bits (599), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 76/268 (28%), Positives = 124/268 (46%), Gaps = 15/268 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              AA Q        KNA   A L+ +AA   A     PE   A       L        
Sbjct: 3   FKAAAIQMCSGVDPVKNAADMARLVREAAAQGAVYVQTPEMTGAVQKDRPGLRAVLRDEA 62

Query: 61  EGEFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD--- 115
               +      +K   +   + +  +P   G+  N   +    G +++RY K+H++D   
Sbjct: 63  NDIIVNTASDLAKELGIHVHVGSTAIPLDDGKIANRGFLFGPDGKLISRYDKIHMFDVDL 122

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES     G+E A ++ +   ++G   CYD+RFP+L  AQA+ GA+++ +PAA+
Sbjct: 123 DNGESWRESAVYRPGSE-ARIVSLPFAELGFSICYDVRFPQLFRAQAVAGAQVMTVPAAF 181

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAA-SE 227
            R    E HW  LL ARA++   +++AA +      G +  G S IIDP+G  +AAA   
Sbjct: 182 TRQT-GEAHWEILLRARAIENGMFVIAAAQAGKHEDGRETFGHSMIIDPWGKVLAAAGGT 240

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
             A+++AE+    V+    ++P L N R
Sbjct: 241 GEAVLVAEIDVAAVKSAHDKIPNLKNAR 268


>UniRef50_B6YW48 Carbon-nitrogen hydrolase n=4 Tax=cellular organisms
           RepID=B6YW48_THEON
          Length = 264

 Score =  235 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 69/273 (25%), Positives = 113/273 (41%), Gaps = 21/273 (7%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVK--SA 57
           M VA  Q        EKN      L+ +AA+  A L  LPE      + ++   V+  + 
Sbjct: 1   MRVAYVQMEPKLLEPEKNYSKAERLIKEAAKEGAKLVVLPELFDTGYNFESRDEVESVAG 60

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-G-NIVARYAKLHLYD 115
           Q+ +GE    L   ++   +  +         GR +N  V +   G   + +Y K+HL+ 
Sbjct: 61  QIPDGETTEFLVELARDLEVFIVAGTAEKDEKGRLYNSAVIVGPIGWGYIGKYRKVHLF- 119

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +E    ++GN    +  +  +KVG+M C+D  FPE A   AL+GAEI+  P+  V 
Sbjct: 120 ---YREKLFFESGNLGFHVFNIGIVKVGVMICFDWFFPESARTLALKGAEIIAHPSNLVM 176

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIA-AASEMPA 230
                      +  RAL+   Y + A   G +     IG+S I  P    +A  + +M  
Sbjct: 177 PYAPRA-----MPIRALENRVYTITANRIGEERGLRFIGKSTIASPKAEVLAVGSEDMEE 231

Query: 231 LIMAEVTPERVRQVR--AQLPVLNNRRFAPPQL 261
           + + E+     R  R      +  +RR     L
Sbjct: 232 IGVVEIDLNLTRDKRLNELNDIFKDRRPEFYLL 264


>UniRef50_A8RJL1 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RJL1_9CLOT
          Length = 254

 Score =  234 bits (598), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 73/261 (27%), Positives = 118/261 (45%), Gaps = 17/261 (6%)

Query: 1   MLVAAGQFAVTS--VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M VA  QFAV      E+       ++         L  LPE          +   K ++
Sbjct: 1   MKVAIVQFAVNDEESKEQKIIRMEGILDNL--KGTDLIVLPELWNIGF-FAYEEYAKQSE 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYDAF 117
           LL G     L R++K                 + +N   +  + G ++  Y K+HL+ A 
Sbjct: 58  LLTGPTFSSLARKAKELGSYIFTGSISEQDGDKCYNTAGLIDREGRLLGTYRKMHLFAA- 116

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E + ++ G++   +++ E  K+G+  CYD+RFPEL   +   GAEILV  A W    
Sbjct: 117 ---ERQYMERGDKPV-VIDTEFGKIGMSICYDIRFPELFRKEVEMGAEILVNCAGWPYP- 171

Query: 178 LKEHHWSTLLAARALDTTCYMVAA----GECGNKNIGQSRIIDPFGVTIAAASEMPALIM 233
            +   W+ L   RA++  CYM++        GN  IG+S +IDP+G   AAA  M  ++ 
Sbjct: 172 -RVESWNMLHPVRAMENQCYMLSCCCAGASRGNPFIGRSMVIDPWGTVQAAAGNMETVVK 230

Query: 234 AEVTPERVRQVRAQLPVLNNR 254
           +E+ PE++  +R     L +R
Sbjct: 231 SEIFPEQLAGIRETFTALKDR 251


>UniRef50_C4QCM8 Nitrilase-related n=1 Tax=Schistosoma mansoni RepID=C4QCM8_SCHMA
          Length = 541

 Score =  234 bits (598), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 80/289 (27%), Positives = 126/289 (43%), Gaps = 31/289 (10%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  V +    N +  + L+++A  E+   L  LPE         A      A+ 
Sbjct: 253 LRLALVQMFVGADKPANIKRASELISRAVSEHSPHLVCLPECF--TSPIGAKYFGPYAEA 310

Query: 60  LE-GEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLV-ALQAGNIVARYAKLHLYDA 116
           +  G     L   +K + +  +   I      G+ +N        G +V  Y KLHL+D 
Sbjct: 311 VPNGPSCQMLSDAAKLHKIWLVGGSIPERGPDGKLYNCCATYNPDGELVGLYRKLHLFDI 370

Query: 117 -----FAIQESRRVDAGNEIAPLLEVE---------GMKVGLMTCYDLRFPELALAQALQ 162
                FA +ES  + +G E     E+           ++VG+  CYD+RFPEL+L  A Q
Sbjct: 371 DIPGQFAFKESASLSSGKETFS-FEIPLKNSENKISVIRVGIGICYDIRFPELSLLYANQ 429

Query: 163 -GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN---KNIGQ--SRIID 216
            G ++L+ PAA+        HW  L  ARALDT CY+       N     I    S I  
Sbjct: 430 LGCQLLLFPAAF-NPKTGSLHWELLGRARALDTQCYVGMCSPACNLELDYISHAESLITS 488

Query: 217 PFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR---FAPPQLL 262
           P+G+ IA   +   +I A++    ++ VR  +P+   RR   +  P+L+
Sbjct: 489 PWGIVIAKGGKEEEIITADLDFSELKCVRESIPIGRQRRLDIYTTPKLV 537


>UniRef50_C9KQR5 Hydrolase, carbon-nitrogen family n=1 Tax=Mitsuokella multacida DSM
           20544 RepID=C9KQR5_9FIRM
          Length = 259

 Score =  234 bits (598), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 72/266 (27%), Positives = 113/266 (42%), Gaps = 14/266 (5%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M ++  Q  V  +  + N +    ++A+A   +  +  LPE                   
Sbjct: 1   MKISILQMPVAFARPDDNIKTLRRMVAEAMRAEPDVLVLPELWRLGFYPQPIAVHADLDG 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            +   +  L   ++ N +  +         G+ +N        G  VA Y K HL+    
Sbjct: 61  QQSRTV--LAELARTNGVNIVGGTVANRREGKVYNTCYVFDRTGTEVASYDKTHLFSPSG 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             ES+   AG E+     ++G++ G+  CYD+RFPE     AL+   +L LPAAW    L
Sbjct: 119 --ESKDFAAGREMVT-FRLDGVRCGVAVCYDVRFPEFIRKLALEDIAVLFLPAAWPASRL 175

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASEMPALIM 233
              HW  L  ARA++   Y++AA E G     N   G S I+DP+G  I  A E  A++ 
Sbjct: 176 S--HWQILTRARAIENQFYVIAANEAGTDEQGNHLAGHSAILDPWGEAIVEAGESEAILT 233

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAPP 259
           A + P   R +R  + V  +RR    
Sbjct: 234 ARLRPGLRRHIRETINVFADRRPELY 259


>UniRef50_C1GYG0 Hydrolase n=1 Tax=Paracoccidioides brasiliensis Pb01
           RepID=C1GYG0_PARBA
          Length = 276

 Score =  234 bits (598), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 73/245 (29%), Positives = 121/245 (49%), Gaps = 18/245 (7%)

Query: 16  KNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRN 75
            N   C  L+ +A E  A    LPEA        ++    +  +    F+  L++E++ +
Sbjct: 3   HNLSQCQILVKKAVEAGAKALFLPEASDYIATSPSETVSLAQPVQRSAFVLGLQKEARES 62

Query: 76  MMTTILTIHVPSTPG-RAWNMLVALQA-GNIVARYAKLHLYD-----AFAIQESRRVDAG 128
            +   + IH P+  G +  N L+ +   G I  RY KLHL+D        ++ES+ V+ G
Sbjct: 63  KIPINVGIHEPAQGGEKVKNTLIWIDEVGEITQRYQKLHLFDVDIKDGPVLKESKSVEKG 122

Query: 129 NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLA 188
             I P       +VGL  C+DLRFPE++L+   Q A+I+  P+A+   P  + HW  LL 
Sbjct: 123 MGILPPFFTPVGRVGLSICFDLRFPEVSLSLRRQSAQIITYPSAFTV-PTGQAHWEPLLR 181

Query: 189 ARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE-----MPALIMAEVTP 238
           ARA++T  Y++AA + G  N      G S I++P+G  +A   +      P + +A +  
Sbjct: 182 ARAIETQSYVIAAAQAGVHNSKRVSYGHSMIVNPWGEVVAELGDGSLSQEPEIAVANIDL 241

Query: 239 ERVRQ 243
           E + +
Sbjct: 242 ELLEK 246


>UniRef50_Q5A428 Nitrilase superfamily protein n=4 Tax=Candida RepID=Q5A428_CANAL
          Length = 299

 Score =  234 bits (597), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 85/292 (29%), Positives = 138/292 (47%), Gaps = 39/292 (13%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A GQ   +S   +N  +   L+ +A    A L  LPEA       +A+ S++ +Q +
Sbjct: 4   LKIAVGQLCSSSNLSQNLRVVKKLLQKAQLEKARLLFLPEATDYI-SRNANHSIELSQEV 62

Query: 61  EGEFLGRLRRESKRNMM--TTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-- 115
           +  FL  L    K         + IH+P    R  N+ V +   G IV+ Y K+HL+D  
Sbjct: 63  QSNFLSPLLDYVKSLNGSTYLSIGIHLPGKK-RVRNVHVLIDPKGAIVSEYQKVHLFDVD 121

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                 ++ES  V+ GN+I   + ++  K+GL  CYD+RFPELAL     G++I+  P+A
Sbjct: 122 VPNGPILKESNSVEPGNKIEDPIPIDDFKLGLGICYDIRFPELALRLRRLGSDIITFPSA 181

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----------------NIGQSRIID 216
           +      E HW  L  ARA+D+ C+++ A +CG                  + G S I+D
Sbjct: 182 FTT-RTGEAHWELLSKARAIDSQCFVINAAQCGQHQVGTDPNDLSKVIKRISYGDSIIVD 240

Query: 217 PFGVTIAAA------------SEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           P+G  +A               +   LI AE+  +    +R  +P+L++RR 
Sbjct: 241 PWGEVLARGEKYTDELKHDDDGDYYELIQAELKLDDSESIRKNMPLLDHRRP 292


>UniRef50_C7TF35 Hydrolase, carbon-nitrogen family n=17 Tax=Lactobacillales
           RepID=C7TF35_LACRL
          Length = 260

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 70/265 (26%), Positives = 117/265 (44%), Gaps = 14/265 (5%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  +     EKN +  A+ +A+AA+  A +  LPE       +D +    +A  
Sbjct: 4   LTIALAQIDIAFGQPEKNFQTVANAVAEAAQQGAEVVVLPEMWNTG--YDLEHLTTTANP 61

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWN-MLVALQAGNIVARYAKLHLYDAFA 118
                   L   +++  +  +      +  G  +N  L   Q G  +A+Y K+H +    
Sbjct: 62  DGLRTKAFLSALAQQYHLAIVGGSVAAAENGHFYNRSLTVDQRGRQLAKYDKVHRFRL-- 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E + + AG          G+   +  CYDLRFPE     A  G ++  LPA W    L
Sbjct: 120 MNEEKFITAGATADHF--TLGVPASVAICYDLRFPEWFRRMASDGTQLFFLPAEWPTPRL 177

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
               ++ LLAARA++   Y+VA    GN       GQS+++DPFG  +    + P + + 
Sbjct: 178 --PQFNALLAARAIENQAYVVAVNRVGNDPNNAFGGQSQVVDPFGERLLKLDDQPQVRIV 235

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
            +  +R+   R Q+PV  +RR    
Sbjct: 236 TIDLDRIAAARQQIPVFTDRRPELY 260


>UniRef50_Q3IFH8 Putative hydrolase, carbon-nitrogen family n=3 Tax=Alteromonadales
           RepID=Q3IFH8_PSEHT
          Length = 275

 Score =  233 bits (596), Expect = 4e-60,   Method: Composition-based stats.
 Identities = 73/270 (27%), Positives = 128/270 (47%), Gaps = 21/270 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALL--ARDDHDADLSVKSAQL 59
            + A Q       E+N +   + + Q       L  LPEA L  ++  +D     K A+ 
Sbjct: 7   TIIALQMCSGVDPEQNIQTLVNQLQQLPTTRPLLVCLPEAFLVFSKSGNDTLKVAKQAE- 65

Query: 60  LEGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWN-MLVALQAGNIVARYAKLHLYDAF 117
               +  +L    + + +      +  P    + +    +    G +VA Y K+HL+D  
Sbjct: 66  ---RYKQQLSELCQLHNIWLSAGTMPEPYNDNKYYAASHLFNAQGELVASYNKMHLFDVT 122

Query: 118 ------AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                 + +ES    AGNE+  +++    K+GL  CYDLRF  L      QGAE++++P+
Sbjct: 123 VDDSTASYRESDFTQAGNEVV-VVDSPFGKIGLTVCYDLRFSALYTQLVRQGAEVILVPS 181

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAAS 226
           A+      + HW  LLAARA++T CY++AA + G      +  G S I+ P+G T++   
Sbjct: 182 AFTV-VTGQAHWQPLLAARAIETQCYVIAAAQYGAHENGRQTYGHSIILSPWGNTLSELP 240

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
                I A +  +++ ++R  +PV +++RF
Sbjct: 241 TGTGFISATLDLKQLHKIRRDMPVQSHQRF 270


>UniRef50_A0BR54 Chromosome undetermined scaffold_122, whole genome shotgun sequence
           n=2 Tax=Oligohymenophorea RepID=A0BR54_PARTE
          Length = 281

 Score =  233 bits (594), Expect = 5e-60,   Method: Composition-based stats.
 Identities = 73/280 (26%), Positives = 122/280 (43%), Gaps = 24/280 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARD-----DHDADLSVK 55
             +A  Q A+T+   +   +    + +AA   + +  L E   +        ++A+   K
Sbjct: 5   FKIACIQNAITATKTQTLALVKDQIKEAAIQGSKVCILGECFNSYYVKAQLQNNAEDFGK 64

Query: 56  SAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYD 115
           + +    + L  +   SK+  +  I +I   S   + +N       G ++  Y K HL+D
Sbjct: 65  TGER---QTLDLISEISKQFGIMIIGSIPEKSGD-KMYNTAFCFNNGQLLVTYRKTHLFD 120

Query: 116 -----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                    +ES    AG+    +++ E  K G+  CYD+RFPELA     +G   LV P
Sbjct: 121 IDIPGKITYKESLTFSAGDNY-KIVDTEYGKFGIGICYDIRFPELAQIMREKGCHFLVYP 179

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC---GNKN-----IGQSRIIDPFGVTI 222
            ++        HW  LL ARA+D  CY+         GN        G S ++DP    +
Sbjct: 180 GSFNL-TTGPLHWELLLKARAVDYQCYVAGVSSARYMGNDESIYKAWGHSTLLDPMAKVL 238

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           A     P++I++EV  + + QVR Q+PV   RR    +L+
Sbjct: 239 ATCEHDPSVIISEVDLDYLEQVRQQIPVSQQRRNDIYELI 278


>UniRef50_A0LH50 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Syntrophobacter fumaroxidans MPOB
           RepID=A0LH50_SYNFM
          Length = 260

 Score =  233 bits (594), Expect = 6e-60,   Method: Composition-based stats.
 Identities = 74/266 (27%), Positives = 113/266 (42%), Gaps = 16/266 (6%)

Query: 2   LVAAG-QFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           LVAA  Q  V     + N       + + A  +  L  LPE       +     V S   
Sbjct: 4   LVAACLQLRVVPGNVDANLANAREGIEELASGECRLVVLPEMWACGFPYSRLQEVASRTP 63

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
              E +  +R  ++R+ M  + ++   S  GR +N    +   G I   Y K+HL+    
Sbjct: 64  ---EVVEEMRGWARRHGMVLVGSLPE-SVDGRIYNTSYVIDANGEIAGSYRKVHLFSLH- 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E      G E + +   E  ++G+M CYDLRFPEL    AL GA I+ + + W    +
Sbjct: 119 -HEDLHFGRG-ETSLVCSTEAGELGVMICYDLRFPELGRKLALDGARIMCVSSHWPD--I 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
           +  HWS LL ARA++   +++    CG +      G S II P G  +  A   P  I A
Sbjct: 175 RIDHWSLLLRARAVENQLFVIGCNGCGTEKKMRYGGASAIISPMGKVLIEAGTGPESIAA 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
            +  E V + R  +    +R  A  +
Sbjct: 235 ALDMEEVDRFRKLITCFPDRVPAVYE 260


>UniRef50_A4J4S3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfotomaculum reducens MI-1
           RepID=A4J4S3_DESRM
          Length = 273

 Score =  232 bits (593), Expect = 7e-60,   Method: Composition-based stats.
 Identities = 70/272 (25%), Positives = 113/272 (41%), Gaps = 17/272 (6%)

Query: 1   MLVAAGQF-AVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSA 57
           + +   Q   V      N       + QAA   A +  LPE        D   D   +  
Sbjct: 5   LTIGLIQMDCVLGDVAANVAKAIERIRQAAAMGAQIICLPELCTTGYRPDLLEDKLWELT 64

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPST-PGRAWNMLVALQ-AGNIVARYAKLHLYD 115
           + + G       + +K   +  IL ++     PG   N  V +   G +   + K H   
Sbjct: 65  EPVPGPTTDVFSQLAKELGIYIILPMNEKGAVPGMIHNSAVFIDKDGEVQGVFRKAH--- 121

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
                E      GN   P+ + E  KVG+M CYD+ FPE+A    L+GAE++  P+AW +
Sbjct: 122 -AYATERYYFTDGNHY-PVFQTEFGKVGVMICYDMGFPEVARILTLKGAEVIFAPSAWRQ 179

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASE-MPA 230
               E  W   +AARAL+   ++ A    G +      G+S+I +  G T+A A+     
Sbjct: 180 E--DEDIWDINIAARALENRLFVAAVNRVGREGDVVMHGKSKIANTRGKTLAEAARFEED 237

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           +++A V    +   R + P L +R+ A   L+
Sbjct: 238 ILVATVDLHELIAGRRETPYLKDRKPASYGLI 269


>UniRef50_C1B562 Putative hydrolase n=2 Tax=Actinomycetales RepID=C1B562_RHOOB
          Length = 278

 Score =  231 bits (591), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 85/253 (33%), Positives = 113/253 (44%), Gaps = 19/253 (7%)

Query: 18  AEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMM 77
                 L+  AA   A L  LPE   A    D D     A+ L+G FL  + R +KRN +
Sbjct: 32  IRRVDDLIDDAA--GADLVVLPELW-AHGGFDYDTWTDRAEPLDGTFLETMSRAAKRNSI 88

Query: 78  TTILTIHVPSTPG----RAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIA 132
                  +         R WN  V     G I A Y K+H +  F+  E R + AG E  
Sbjct: 89  WLHAGSIIERENDTASARLWNTSVVFDPDGEIRATYRKIHRF-GFSDGEPRLLTAGTEPV 147

Query: 133 PL-LEVEGMK---VGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLA 188
              L         VGL TCYDLRFPEL       G E+LV+PAAW R   +  HW+ L  
Sbjct: 148 STGLATAAGAETVVGLSTCYDLRFPELYRELVGAGTEVLVIPAAWPRA--RVEHWTALGR 205

Query: 189 ARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQV 244
           ARA++   Y+V     G        G S+I+ P G  +AAA +   +I A +    +R++
Sbjct: 206 ARAIENQTYVVQCNVAGVDGDVALGGHSQIVAPDGTVVAAAGDSADMISATLELGSLREL 265

Query: 245 RAQLPVLNNRRFA 257
           R   PVL +RR  
Sbjct: 266 RRTFPVLADRRLG 278


>UniRef50_B7G2G6 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7G2G6_PHATR
          Length = 308

 Score =  231 bits (591), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 75/295 (25%), Positives = 130/295 (44%), Gaps = 41/295 (13%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            +A  Q   TS    N    A     A  + A++  LPE      +  +    ++   ++
Sbjct: 14  RIAVAQLRSTSDKFSNLLDVARCAGWAKRDGAAMLFLPECCCFLGESASQTLEEADPPIQ 73

Query: 62  GE---FLGRLRRESKRNMMTT-ILTIHVPSTP---------GRAWNMLVALQA-GNIVAR 107
                 L  LR  ++ + +      IHV   P          R +N  + +   G +   
Sbjct: 74  DADILILDGLRNIARESGLWISAGGIHVSGAPPHDTADPDHSRVYNTHLIIDCVGTVKCL 133

Query: 108 YAKLHLYDAF-----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQ 162
           Y K+HL+D       +++ES     G +   + +     +G+  CYDLRFPE+ +    Q
Sbjct: 134 YRKIHLFDVEIPGQVSLRESATTAPG-KAVKVCDSPIGCLGVTICYDLRFPEMYVKLTTQ 192

Query: 163 GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDP 217
           GA+IL++P+A+   P    HW TLL ARA++  C+++AA + G  N      G + I+DP
Sbjct: 193 GAQILLVPSAFTI-PTGTAHWHTLLRARAIENQCFVIAAAQFGEHNHKRESYGHALIVDP 251

Query: 218 FGVTIAAASE---------------MPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
           +G  +A A                  P++++ E+  + V   R ++P+ N+RR A
Sbjct: 252 WGEVLADAGGADGGGTVSIDASNLVTPSIMVQEIDLDLVTSARQRIPIQNHRRAA 306


>UniRef50_Q65KK0 Methylthioribose recycling protein n=1 Tax=Bacillus licheniformis
           ATCC 14580 RepID=Q65KK0_BACLD
          Length = 259

 Score =  231 bits (591), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 71/261 (27%), Positives = 116/261 (44%), Gaps = 14/261 (5%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + ++  QF +      +N +    L+ Q     A +  LPE      D     S+   + 
Sbjct: 3   LTISCLQFDIAYGNPSENFKKAEQLIEQ-ESRKADILLLPELWTTGYDLKNLGSIADEEG 61

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWN-MLVALQAGNIVARYAKLHLYDAFA 118
            +      L+  +K N +  +            +N M +A + G+++  Y+K HL+    
Sbjct: 62  RQ--TKRWLQETAKANRIHIVCGSVAVKKKSGVYNIMYIADKNGHLIKEYSKAHLFQL-- 117

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E   + AG+      E+EGM      CYD+RFPE       +GA I+ + A W    L
Sbjct: 118 MDEHLYLSAGSGDGR-FELEGMPAAGFICYDIRFPEWIRKHTSEGAGIIFVSAEWPLARL 176

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMA 234
              HW +LL ARA++  C++ A    G    N+  G S +IDP G T+A A    A+I A
Sbjct: 177 --DHWQSLLKARAIENQCFVAACNRSGKDPANEFAGHSTVIDPLGRTLAEAGRGEAVIRA 234

Query: 235 EVTPERVRQVRAQLPVLNNRR 255
           E+    + + R Q+PV  + R
Sbjct: 235 EIDLRDIEKARGQIPVFEDIR 255


>UniRef50_A8LPZ9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=28 Tax=Alphaproteobacteria RepID=A8LPZ9_DINSH
          Length = 277

 Score =  231 bits (591), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 71/269 (26%), Positives = 106/269 (39%), Gaps = 20/269 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M  A  Q       E N      L AQA    A     PE                 +  
Sbjct: 1   MRAALVQMTSGDDPEANLAQLQGLAAQAVAEGAGFVLSPEVSNCLSTSRTRQRAVLRREA 60

Query: 61  EGEFLGRLRRESKRNMMTTILT---IHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD- 115
           +   L  +R  + R  +  +L    +      GR  N  + + A G I ARY K+H++D 
Sbjct: 61  DDPMLAAMREFAARRGVWVLLGSLAVTTEDAEGRFANRSILIDAGGGIAARYDKIHMFDV 120

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
               A   +ES     G+  A L +    K+G+  CYDLRFP L    A  GAEIL +P+
Sbjct: 121 AVSEAETYRESDGYRPGDR-AVLADTPFGKIGMTVCYDLRFPHLFRDLARAGAEILTVPS 179

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK---------NIGQSRIIDPFGVTI 222
           A+        HW  LL ARA++   +++A  + G             G S  +DP+G  +
Sbjct: 180 AF-SPVTGAAHWEPLLRARAIECGAWVLAPAQTGTHPATRGKARSTHGHSLAVDPWGRVL 238

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVL 251
           A     P +   ++    +   R ++P L
Sbjct: 239 ADGGTAPGVCFVDLDRTEIAAARRKIPSL 267


>UniRef50_Q11146 UPF0012 hydrolase Rv0480c/MT0498 n=34 Tax=Actinomycetales
           RepID=Y480_MYCTU
          Length = 340

 Score =  231 bits (591), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 84/270 (31%), Positives = 128/270 (47%), Gaps = 21/270 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q    +    N ++      +AA   A L   PEA + R         + A+ +
Sbjct: 61  MRIALAQIRSGTDPAANLQLVGKYAGEAATAGAQLVVFPEATMCRLGVP---LRQVAEPV 117

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG---NIVARYAKLHLYDAF 117
           +G +   +RR +    +T I  +  P+  GR  N L+A   G      A Y K+HLYDAF
Sbjct: 118 DGPWANGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIHLYDAF 177

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              ESR V  G E    + V+G++VGL  CYD+RFP L    A +GA+++ + A+W  GP
Sbjct: 178 GFTESRTVAPGREPVV-VVVDGVRVGLTVCYDIRFPALYTELARRGAQLIAVCASWGSGP 236

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECG--------------NKNIGQSRIIDPFGVTIA 223
            K   W+ L  ARALD+  Y+ AAG+                   +G S +  P G  + 
Sbjct: 237 GKLEQWTLLARARALDSMSYVAAAGQADPGDARTGVGASSAAPTGVGGSLVASPLGEVVV 296

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNN 253
           +A   P L++A++  + V   R ++ VL N
Sbjct: 297 SAGTQPQLLVADIDVDNVAAARDRIAVLRN 326


>UniRef50_A6DN63 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Lentisphaera araneosa HTCC2155
           RepID=A6DN63_9BACT
          Length = 292

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 63/263 (23%), Positives = 117/263 (44%), Gaps = 18/263 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + V   Q + +  +E+N     S++ QA++N   L   PE  L       D++ ++A+  
Sbjct: 26  LRVCLVQMSSSPDFEENLAHAKSIIEQASQNRDELIIFPECAL--LWAKTDITHQNAKTR 83

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA- 118
           E ++   L   SK   +  +          + +N        G+++  Y K HL+  F  
Sbjct: 84  E-QWTDLLSPLSKTYKIAIVWGGLAERQENKVFNSSFIFDADGHLLDVYRKTHLFQIFTP 142

Query: 119 ----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               I E+   + G+    ++++    +G+  CYDLRFPE     A  G ++++  AA+ 
Sbjct: 143 GKKAIDETETYEHGDTGPCVVKINDWSIGISICYDLRFPEFLRNYA--GCDLMINSAAFT 200

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN------IGQSRIIDPFGVTIAAASEM 228
           +   K  HW  L+ ARA++   Y++ + +CG          G S +IDP+G  +    E 
Sbjct: 201 KATGK-AHWEVLMRARAVENQSYVIGSAQCGRNELSGISAYGHSIVIDPWGEVLGDLGES 259

Query: 229 PALIMAEVTPERVRQVRAQLPVL 251
            A     +  + ++Q R  +P L
Sbjct: 260 IASQSFVLNKQIIQQTRETVPAL 282


>UniRef50_Q2NAB0 Nitrilase 1 like protein n=3 Tax=Sphingomonadales
           RepID=Q2NAB0_ERYLH
          Length = 267

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 68/263 (25%), Positives = 112/263 (42%), Gaps = 13/263 (4%)

Query: 8   FAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGR 67
                  E N         +A+   A +   PE  L  D      +   A   +  +  R
Sbjct: 1   MTSGIDPEANFAAIEQAAREASAGGAEMLFTPEMSLLLDRDRKRAAQHIAPQAQSPYPER 60

Query: 68  LRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYD-----AFAIQE 121
           L+  ++   +   +   V     R  N   +    G     Y K+H++D       + +E
Sbjct: 61  LQAIAREAGLWLTVGAPVRVEDDRYANRQWLFYPRGESPVHYDKIHMFDVDLADGESWRE 120

Query: 122 SRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEH 181
           S     G E+  + +    ++GL  CYDLRFP L        A+ + +PAA+ R P    
Sbjct: 121 SNAYRPGEEVVLVDDTPVGRLGLTICYDLRFPALFEELGNARADCIAIPAAFTR-PTGAA 179

Query: 182 HWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAA-ASEMPALIMAE 235
           HW TL+ ARA++ + ++VAA + G         G S ++DP+G  +   + + P L  A+
Sbjct: 180 HWHTLVRARAIEASAFVVAAAQVGEHEDGRKTYGHSLVVDPWGEVLLDMSGDKPGLGFAD 239

Query: 236 VTPERVRQVRAQLPVLNNRRFAP 258
           +   R+ +VR Q+P L NRR  P
Sbjct: 240 IDLARIEEVRRQVPSLANRRPIP 262


>UniRef50_Q972X1 264aa long hypothetical beta-ureidopropionase n=1 Tax=Sulfolobus
           tokodaii RepID=Q972X1_SULTO
          Length = 264

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 67/272 (24%), Positives = 115/272 (42%), Gaps = 19/272 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
           M +A  Q  +T   + N E    L+ +A +N A + AL E                  A+
Sbjct: 1   MRIAIIQTYMTWDKKDNIERQVELVNKAIDNKAKIIALDELSNTIYFPFEQNPKYFSWAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
              GE L R +  SK   ++ I+ I    +    +N    L  G I+ +Y K HL     
Sbjct: 61  TERGETLQRFKEISKEREVSLIVPIFERDSN-FFYNTAFILDNGEIIGKYRKTHLPQEEF 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP--AAWVRG 176
             E      G+   P+ +++G+K G++ C+D  FPE    + ++GA ++ +P  AA+   
Sbjct: 120 FNEYYYFKVGDLGFPIFDLKGVKTGVVICHDRHFPEPVRVEVIKGAWLIFIPSVAAF--- 176

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECG-------NKNIGQSRIIDPFGVTIAAASEMP 229
              +  W   L A A+  T Y+      G        +  G+S II P G  +  A +  
Sbjct: 177 ---KEIWELELKAHAVFNTVYIAGINRFGKEYPNQKEEYFGESMIISPIGEIVTKAEKNE 233

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            ++ A+++ + V   R + P L  +R +   L
Sbjct: 234 EILYADISEDEVINARIKRPFLK-KRLSSYGL 264


>UniRef50_C8NJS3 Carbon-nitrogen hydrolase family protein n=16 Tax=Corynebacterium
           RepID=C8NJS3_COREF
          Length = 294

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 75/267 (28%), Positives = 120/267 (44%), Gaps = 20/267 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q         N E+  +    AA   A L   PEA             + A+ L
Sbjct: 32  MRIALIQITSGGDKMANLELVRTTATDAAAQGARLLIYPEA--TSQAFGTGRLDEQAEDL 89

Query: 61  E-GEFLGRLRRESKRNMMTTILTIHVPSTP--------GRAWNMLVALQAGNIVARYAKL 111
             G F   +++ ++   +  +  +  P+           R  N  +    G +   Y K+
Sbjct: 90  HTGAFATGVQQLAEDLGVVIVAGMFTPADTVEQDGKTLHRVHNTALVTGNG-LHEGYHKI 148

Query: 112 HLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
           + YDAF  +ES  V  GNE+  + +++G+KVG+  CYDLRFP      A  GAEI+V+P 
Sbjct: 149 NTYDAFGYRESDTVKPGNELH-VFDLDGVKVGVAICYDLRFPTQFQELARAGAEIIVVPT 207

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-------GNKNIGQSRIIDPFGVTIAA 224
           +W  G  K      L  ARALD+T +++   +        G   IG S ++DP GV   +
Sbjct: 208 SWQDGEGKLEQLQVLTRARALDSTSWILMCDQARPTEKRKGPAGIGHSMVVDPTGVIADS 267

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVL 251
           A   P  ++A++    ++ +R  +PVL
Sbjct: 268 AGYEPETVIADIDLSNLQDIRKSIPVL 294


>UniRef50_Q47VH0 Hydrolase, carbon-nitrogen family n=1 Tax=Colwellia psychrerythraea
           34H RepID=Q47VH0_COLP3
          Length = 273

 Score =  231 bits (589), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 76/268 (28%), Positives = 127/268 (47%), Gaps = 20/268 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQ--AAENDAS-LFALPEALLARDDHDADLSVKSA 57
           + ++A Q +  +  E N    A L+++  A++ D   L  LPE  L     D++    + 
Sbjct: 2   VKLSAIQLSSAANVETNLAKIAELLSKITASQEDVQHLVVLPECCLYFGSKDSEQLDLAI 61

Query: 58  QLLEGE----FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHL 113
               G      LG L ++ K  ++   + I   S+     +  V    G ++ +Y K+HL
Sbjct: 62  ASATGNDLCLALGELAKKFKVYLVAGTIPILSTSSTKFTNSSCVFNPEGELIGQYDKIHL 121

Query: 114 YDAF------AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +D        +  ESR   AG EI+ +   E   +GL  C+DLRFP L    ++ GA+I+
Sbjct: 122 FDVNVSDSTKSYCESRYTQAGKEISMV-NTEFANIGLSVCFDLRFPNLFQQLSIAGADII 180

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGE-----CGNKNIGQSRIIDPFGVTI 222
            +P+A+ R   K  HW TLL ARA++   Y+VAAG+      G +  G S II+P+G   
Sbjct: 181 TVPSAFTRVTGK-AHWQTLLQARAIENQVYIVAAGQEGVHENGRETWGHSMIINPWGEIE 239

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPV 250
            +       I  +   E + ++R  +P+
Sbjct: 240 QSIETGEGYISIDYHSEELTRIRQSMPL 267


>UniRef50_B6B254 Hydrolase in PqqF 5'region n=1 Tax=Rhodobacterales bacterium
           HTCC2083 RepID=B6B254_9RHOB
          Length = 261

 Score =  231 bits (589), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 68/267 (25%), Positives = 118/267 (44%), Gaps = 12/267 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q         +NA +     A A   +A L   PE  L   +  AD   K A+ 
Sbjct: 1   MKLAIFQMNSVDRSVTENAALFDQACADAKSGNADLIIFPEMALTGYNIGADRIRKLAEP 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
            +G  +  LR  +K + +  +          + +N  V +  AG++++   K HL+    
Sbjct: 61  CDGPMIQTLRDMAKHHRIGVVCGFPELDGE-QVFNAAVIIDAAGSVLSICRKAHLFGDV- 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             +       + + PL++     VG   CYD+ FPEL  A AL GA+I+++P A +   +
Sbjct: 119 --DRAAFSPADTLCPLVQFGDWSVGFAICYDVEFPELVRAYALAGADIVLVPTANMLPYV 176

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMA 234
                + ++ ARA +   Y+  A   G     +  G S ++ P G  +A A     L++A
Sbjct: 177 GIA--TRVVPARAEENEIYVAYANRVGREGAFEYCGLSCVVGPDGNDVARAGRNEELMIA 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +++ E +  +R+ L  LN+RR     L
Sbjct: 235 DISKETIAHIRSSLSHLNDRRSDLYPL 261


>UniRef50_A9B254 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B254_HERA2
          Length = 259

 Score =  230 bits (587), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 73/265 (27%), Positives = 113/265 (42%), Gaps = 14/265 (5%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + VA  Q   V    E N      L A+A    A+L  LPE  L    +  + + + +  
Sbjct: 3   LTVALAQIDLVLGDREANLATVRQLAARAEMAGAALLVLPE--LWGTGYLLEQAHELSDP 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
           L       +   + R+ +  + ++       + +N      A G  +  Y K HL     
Sbjct: 61  LGKGLFEEVAVLAARHHLAIVGSLLERDGE-QVYNTATLYDAQGKRLHSYRKTHL--IGL 117

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           +QE R + AG + A + E          CYDLRFPEL    AL GA ++++PA W     
Sbjct: 118 MQEDRYLAAGQQ-AEVFETAWGTSACAICYDLRFPELFRRYALAGAGVIIIPAEWP--TA 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMA 234
           +  HW TLL ARA++    ++A    G    N+  G S +IDP+G  +    +   L+ A
Sbjct: 175 RIEHWRTLLRARAIENQAVVIACNRVGSDRANQFGGHSVVIDPWGKVLVEGDDQAGLLTA 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
            V    + + R  LPV  +RR    
Sbjct: 235 TVDLASIAKARDFLPVFRDRRVELY 259


>UniRef50_A9UWV2 Predicted protein (Fragment) n=1 Tax=Monosiga brevicollis
           RepID=A9UWV2_MONBE
          Length = 270

 Score =  230 bits (587), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 70/259 (27%), Positives = 117/259 (45%), Gaps = 17/259 (6%)

Query: 19  EICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMT 78
              A L AQAA+    +  LPEA         + +   A       L R     K++ + 
Sbjct: 4   RRIADLFAQAAKAQCRMLFLPEAFDWIG-LPVEETKSRAVPTTHAALTRYWDLCKQHSIW 62

Query: 79  TILTIHVPSTPG---RAWNMLVALQA-GNIVARYAKLHLYDA----FAIQESRRVDAGNE 130
                    T     R  N  V +   G + + Y K+HL+D        +ES     G  
Sbjct: 63  ASFGGAHVQTDDPQKRIANRHVIVDPLGQVRSTYDKIHLFDVDTADGVFKESDFTQPGRT 122

Query: 131 IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAAR 190
           +  + +     +GL  CYD+RFPE+      +GA++L++P+A++    K  HW  LL AR
Sbjct: 123 LVTVPDTPLGTLGLSICYDVRFPEVYTELRARGADVLLVPSAFMPSTGK-AHWEALLRAR 181

Query: 191 ALDTTCYMVAAGECGNK------NIGQSRIIDPFGVTIAAAS-EMPALIMAEVTPERVRQ 243
           A++T C+++AA + G        + G S ++DP+G  +     E   L+   +  ER+ +
Sbjct: 182 AIETQCFVIAAAQAGTHAPSTRRSYGHSLVVDPWGDVLVDGDAENEGLLAVTIDLERITE 241

Query: 244 VRAQLPVLNNRRFAPPQLL 262
           VR ++P+ N+R+  P  L 
Sbjct: 242 VRTKMPLANHRQAVPRHLF 260


>UniRef50_D1VW19 Hydrolase C26A3.11 n=1 Tax=Peptoniphilus lacrimalis 315-B
           RepID=D1VW19_9FIRM
          Length = 264

 Score =  230 bits (587), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 59/260 (22%), Positives = 106/260 (40%), Gaps = 10/260 (3%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             V   Q A     + N +    L+  A +  A + ALPE       +      K  +  
Sbjct: 4   FKVGMIQIASKGDKDYNLKRMEELVDIACQKGADVVALPEMWNCPYQNS--YFTKFKEQE 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAI 119
             E    +++ +KR  +  +      S   + +N      A G  +  Y+K++L+D    
Sbjct: 62  GEESYELMKKLAKRYGIYLVGGSIPISDGDKIYNKSFVFNACGKEIFSYSKINLFDIEGF 121

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +ES  +  G  +  + + E    GL+ CYD RFPEL  +    GAE++ +P+ ++    K
Sbjct: 122 KESDTITGGKSLG-VFQTEFANAGLLICYDSRFPELFQSLVNFGAEVIFMPSTFMIKTGK 180

Query: 180 EHHWSTLLAARALDTTCYMVAA-----GECGNKNIGQSRIIDPFGVTIAAASEMPALIMA 234
              W     ARA+DT C++++       E        S I  P+G  +    E   + + 
Sbjct: 181 RF-WELCNRARAMDTQCFLISPSIARDNELSKNAWAHSMITSPYGEVLLDMGEDEGVEVF 239

Query: 235 EVTPERVRQVRAQLPVLNNR 254
            +  + V++ R   P   +R
Sbjct: 240 SIEADLVKEARKNFPYKKSR 259


>UniRef50_UPI0001BC35FB amidohydrolase n=1 Tax=Butyrivibrio crossotus DSM 2876
           RepID=UPI0001BC35FB
          Length = 258

 Score =  230 bits (586), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 57/266 (21%), Positives = 110/266 (41%), Gaps = 16/266 (6%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +   Q  +     E+N       +   +++   L   PE  +       +      + 
Sbjct: 1   MRIGICQTDIFFEDKERNLNAAEKYIKAVSDSKVRLALFPEMSMTGFTMKPECFY---ED 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            +G     + + + +  +            G  +N  V +   G I+  Y K+H +    
Sbjct: 58  EKGRTYSVMAKLASKYNIYIGYGYISRKNSG-YYNTYVIIDNLGKIICSYDKIHPFTYAG 116

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E R  + G+ ++   +++ + V  + CYDLRFPEL   +A + A+++ + A +  G  
Sbjct: 117 --EDRVYEKGSSLS-FCQIDDITVCPLICYDLRFPELF-IKASKKADLITVAANF--GGP 170

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
           ++ HW  LL ARA++   Y+      G       +G S  + P G  I+ A E   +I+A
Sbjct: 171 RDGHWQVLLKARAIENQTYIAGINRAGEDVSTYYMGHSMAVSPKGDVISMAGEKEDIIIA 230

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
           ++  E   + R + PV N+ R    +
Sbjct: 231 DIDKEEEYEYRKKFPVRNDFRPEIYK 256


>UniRef50_A6UCF8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Rhizobiales RepID=A6UCF8_SINMW
          Length = 285

 Score =  230 bits (586), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 79/268 (29%), Positives = 120/268 (44%), Gaps = 15/268 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              AA Q        +NAE  A L+ +AA   A     PE   A     + L        
Sbjct: 3   FKAAAVQMCSGVDPARNAETMAELVREAALRGAGYVQTPEMTGAIQRDRSGLRSILRDEA 62

Query: 61  EGEFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD--- 115
               + +  R +    +   + +  +    G+  N   +    G  +  Y K+H++D   
Sbjct: 63  NDIVVRKAARLAGELAIYLHVGSTPIALADGKIANRGFLFGPDGAKICEYDKIHMFDVDL 122

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES     G   A + ++   K+G   CYD+RFPEL   QA+ GAEI+ +PAA+
Sbjct: 123 ENGESWRESAAYHPGAT-ARIADLPFGKLGFSICYDVRFPELFRQQAVAGAEIMSVPAAF 181

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAAS-E 227
            R    E HW  LL ARA++   ++VAA + G      +  G S IIDP+G  +A A   
Sbjct: 182 TRQT-GEAHWEILLRARAIENGLFVVAAAQGGTHEDGRETFGHSMIIDPWGRVLAQAGRT 240

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
              +I+AE+ P  V   RA++P L N R
Sbjct: 241 GEEIIIAEIDPLAVHTARAKIPNLKNAR 268


>UniRef50_B2HTJ8 Predicted amidohydrolase n=18 Tax=Acinetobacter RepID=B2HTJ8_ACIBC
          Length = 274

 Score =  229 bits (585), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 76/278 (27%), Positives = 118/278 (42%), Gaps = 26/278 (9%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           LV+  Q       E N ++  SL+ Q+   +ASL   PE  +      A    ++A+  E
Sbjct: 3   LVSVVQMNSQDDIESNFQVIESLIQQSKAQNASLIVFPENFVC---FAAGKQRETAEQFE 59

Query: 62  GEFLGRLRRESKRNMMTTILTI----HVPST----PGRAWNMLVALQAGNIVARYAKLHL 113
                RL + + +  +  +         P       GR   + + +      ARY K+HL
Sbjct: 60  S-IQQRLEKLAHQYQIWIVAGTLPCPFRPDGSIIQDGRVRTVSLCISPERTEARYDKIHL 118

Query: 114 YDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +D          QESR  + G ++  +       +GLM CYDLRFPELAL    QGA +L
Sbjct: 119 FDVQVGDAVGGYQESRFFEPGTDVV-VTSTPFGNIGLMVCYDLRFPELALTLRQQGAHLL 177

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTI 222
             PAA+      + HW  LL ARA+D+ CY++ A + G      +  G +   D  G  +
Sbjct: 178 TAPAAFTY-TTGQMHWQLLLQARAMDSQCYVLGAAQQGWHGEKRQTWGHAGATDSRGQVL 236

Query: 223 AAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +    E   LI           VR  +P++ +R+    
Sbjct: 237 SMIGYEGNGLITVPFDLAAQELVRTSMPLMMHRKLIHY 274


>UniRef50_C7CES6 Putative N-carbamyl-D-amino acid amidohydrolase n=1
           Tax=Methylobacterium extorquens DM4 RepID=C7CES6_METED
          Length = 300

 Score =  229 bits (585), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 109/271 (40%), Gaps = 21/271 (7%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA--DLSVKSA 57
           + VA  Q A      + N      L+ QAA++ ASL  LPE        +   +    + 
Sbjct: 18  ITVACIQMAPRFGDTDANVARSLDLIGQAADDGASLVVLPELTNTGYVFETREEALALAE 77

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
            + +G       + +    +  +  +         +N  V +     +  Y K+HL+D  
Sbjct: 78  TVPDGPTCRAWAKIAAERSLHIVAGMTEREGSS-LYNSAVVIGPEGYIGTYRKMHLWDY- 135

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E+   + GN+  P+ E     +G+  CYD  FPE     ALQGA+I+ +P  WV  P
Sbjct: 136 ---ENLYFEPGNKGLPVFETALGAIGVAICYDGWFPETYRLLALQGADIVCVPTNWVPIP 192

Query: 178 ----LKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIA--AASE 227
                +E   + L  A A   + ++  A   G +     +GQS I+   G   A  A+  
Sbjct: 193 GQVAGREAMANILAMAAAHTNSLFIACADRVGTERGQAFLGQSLIVSHTGWPAAGPASRT 252

Query: 228 MPALIMAEVTPERVRQVRA---QLPVLNNRR 255
              ++ AE+     R+ R       VL +RR
Sbjct: 253 DEDIVSAEIDLGAARRARRWNSFNEVLRDRR 283


>UniRef50_Q4Q8W4 Nitrilase, putative n=7 Tax=Trypanosomatidae RepID=Q4Q8W4_LEIMA
          Length = 279

 Score =  229 bits (585), Expect = 7e-59,   Method: Composition-based stats.
 Identities = 64/270 (23%), Positives = 107/270 (39%), Gaps = 12/270 (4%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           V   Q AVT     N +   +++ +AA+  + L  LPE                A     
Sbjct: 7   VTLCQMAVTREKAANIKKAVTMITEAAKRGSKLAVLPECFNCPYGTKYFDEYSEALAPGN 66

Query: 63  EFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLY----DA 116
           E    + + +K N +  +   I   S  G+ +N  +     G +   + K+HL+    D 
Sbjct: 67  ETFDAMSQCAKANSIWIVAGSIPEKSADGKLFNSSMTFGSDGALKHVHRKVHLFCINTDT 126

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
               ES  + AGN+   +   E  K G+  C+D+R+P LA   A QG   +V P A+   
Sbjct: 127 VRFDESEVLSAGNDATAISLDEHTKFGVAICFDIRYPFLAWKYAEQGTSFIVYPGAFNM- 185

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPAL 231
                HW     ARA+D   Y+       + +      G S ++DP G  ++   E    
Sbjct: 186 VTGPMHWQLAARARAVDNQQYVFVCSPARDTSAEYVAWGHSMVVDPIGNVLSELDEKEGF 245

Query: 232 IMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +  +V    ++  R ++P+L   R     L
Sbjct: 246 VDWKVDLSVIQDTRNRIPILKGVRDDLYTL 275


>UniRef50_A6TPX2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Clostridia RepID=A6TPX2_ALKMQ
          Length = 269

 Score =  229 bits (585), Expect = 7e-59,   Method: Composition-based stats.
 Identities = 64/261 (24%), Positives = 116/261 (44%), Gaps = 11/261 (4%)

Query: 3   VAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           VA  Q     +  E N +     + QAA  +  L  LPE          +   + A+  +
Sbjct: 4   VAGIQMTPIMNDVEANLKRGQHFIQQAAAQEVDLIVLPELWTTGYYLSKESFKQLAEHKD 63

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQ 120
           G  +  ++ ++ R+  + I      +   + +     +   G +     K  L+     +
Sbjct: 64  GRTVTLMQDQALRSNASIICPFVEITEDKKLYIAAAVIDHRGELRGTVHKSLLWG----R 119

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           E +  + GN   P+ + +  KVG++ CY++ FPE +   ALQG E++V P+ W       
Sbjct: 120 EQQIFEEGNIEYPVFDTKIGKVGILICYEMEFPETSRLLALQGVEMIVCPSVWSLS--AS 177

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEM-PALIMAEVTPE 239
           H W   L ARALD T Y+      GN + G+S+++ P G  +A AS+    L++  +  E
Sbjct: 178 HRWDIQLPARALDNTVYVFGVNTVGNNSCGKSKLVSPLGDVLAEASDRKEELLIRAIDKE 237

Query: 240 RVRQVRAQLPVLNN--RRFAP 258
            +   R  +P L++  ++  P
Sbjct: 238 ALDWARETVPYLHDYEKKLTP 258


>UniRef50_B0KGW5 N-carbamoylputrescine amidase n=60 Tax=Bacteria RepID=B0KGW5_PSEPG
          Length = 298

 Score =  229 bits (585), Expect = 7e-59,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 98/279 (35%), Gaps = 20/279 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSA--- 57
           + +A  Q   +     N +    L+ QAA   A +  L E                A   
Sbjct: 4   LRIATTQMPCSWNLPDNLDRAEQLVRQAAAKGAQVILLQELFATPYFCIEQNHQHQALAQ 63

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
              +   L R    +    +   L+ +  +      ++ VA   G ++  Y K H+ +A 
Sbjct: 64  PYPDSPILQRFAALAGELGVVLPLSWYERAGNAFFNSLTVADADGRLLGVYRKTHIPNAI 123

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
             QE      G+    + +    ++G+  C+D  FPE A   AL GAE+L+ P A    P
Sbjct: 124 GYQEKEYFSPGDTGFKVWDTAFGRLGIGICWDQWFPETARCLALMGAEVLLFPTAIGSEP 183

Query: 178 L-----KEHHWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRIIDPFGVT 221
                    HW   +   A      +VAA   G +             G S I D  G  
Sbjct: 184 GCAELDSRDHWQVAMRGHAAANLLPVVAANRVGEEVAASDAALAMRFYGSSFICDHKGAM 243

Query: 222 IAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +A A  +   + + ++    +R+ R    +  +RR    
Sbjct: 244 LAEADRDSSGIWLHDLDLAGMREDRLSWGIFRDRRPEMY 282


>UniRef50_C1E770 Predicted protein (Fragment) n=1 Tax=Micromonas sp. RCC299
           RepID=C1E770_9CHLO
          Length = 316

 Score =  229 bits (584), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 68/306 (22%), Positives = 120/306 (39%), Gaps = 47/306 (15%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA---------- 50
           + VA  Q  V      N     + +  AA   A+L  LPE       +D+          
Sbjct: 8   VKVALLQLPVGEDKSLNIANARAAIEDAAREGAALVVLPEMWNCPYSNDSFPSYAEIIGP 67

Query: 51  -----------------DLSVKSAQLLEG-----EFLGRLRRESKRNMMTTILTIHVP-- 86
                            +   + +   +G       +  L   + R  +  +        
Sbjct: 68  APGRWTGGGGTLAKEDDEDGDEKSAPGDGVGSDAASVAMLSNAAARLGVVVVGGSVPERC 127

Query: 87  STPGRAWNML-VALQAGNIVARYAKLHLYDA-----FAIQESRRVDAGNEIAPLLEVEGM 140
           +  G  +N   V    G ++ ++ K HL+D       + +ES  +  G E+  +++    
Sbjct: 128 ADTGALYNTCCVFDSDGCLLGKHRKTHLFDVDIPGEISFKESDVLSPGTELT-VVDTAVG 186

Query: 141 KVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVA 200
           ++G+  C+D+RFPELA+A A +GA+I+V P A+        HW  L  ARA+D   +++ 
Sbjct: 187 RLGIGICFDVRFPELAMACANRGAQIMVYPGAFNT-VTGPLHWELLQRARAVDNQMFVLT 245

Query: 201 AGE-----CGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
                    G +  G S  + P+   IA   E P  +  E+  E++R  R  +P+   RR
Sbjct: 246 CSPSRVPGAGYQAWGHSTAVGPWAEVIATTDEKPGTVHCELDMEQIRVRRRNMPLEKQRR 305

Query: 256 FAPPQL 261
               +L
Sbjct: 306 GDVYEL 311


>UniRef50_A7FDR9 Hydrolase, carbon-nitrogen family protein n=45
           Tax=Enterobacteriaceae RepID=A7FDR9_YERP3
          Length = 289

 Score =  229 bits (584), Expect = 9e-59,   Method: Composition-based stats.
 Identities = 68/269 (25%), Positives = 114/269 (42%), Gaps = 19/269 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q         N       + Q       L   PE  L    + A     + Q  +G
Sbjct: 6   VALLQLCSGENTRDNLAQIEQQIKQL-NAGIKLVMTPENAL-LFANAASYRHHAEQHNDG 63

Query: 63  EFLGRLRRESKRNMMTTILT----IHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDA-- 116
                +R  ++R  +   +     +   S      + L+    G + ARY K+H++D   
Sbjct: 64  PLQQEVREMARRYGVWIQVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKIHMFDVDI 123

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES     G ++  +++    ++G+  CYDLRFP L  A   QGAEI+ +PAA
Sbjct: 124 NDIHGHYRESDTYQPGQQLT-VVDTPVGRLGMTICYDLRFPGLFQALRAQGAEIISVPAA 182

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW TLL ARA++  C ++AA + G         G +  +D +G  I    +
Sbjct: 183 FTK-MTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGHNPD 241

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             A +   +    ++ +R Q+PV+ + RF
Sbjct: 242 AVAALKVRIETAGLKTIRNQMPVMQHNRF 270


>UniRef50_C7YHV7 Putative uncharacterized protein n=2 Tax=Nectriaceae
           RepID=C7YHV7_NECH7
          Length = 294

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 78/294 (26%), Positives = 126/294 (42%), Gaps = 43/294 (14%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           + A GQ   T+  + N E C  L+A+AA   A +  LPEA              +     
Sbjct: 3   IAAVGQICSTASVKGNLEQCVRLVAKAARGGAKVLFLPEASDYIAPDGQTSLELAEPQQT 62

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTP------GRAWNMLVALQ-AGNIV--ARYAKLH 112
             F+  L+  ++ + +   + IH    P       R  N  + +   G +V  A Y KLH
Sbjct: 63  SPFVKGLQDAAREHSVAVHVGIHHRPEPEPGAAVHRILNRALYIGADGAVVDSASYDKLH 122

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQG--------- 163
           ++D   ++ES  V  G  + P  +    ++G + C+DLRFPE  L  +  G         
Sbjct: 123 VFDYGNLRESATVRPGPALTPPFDSPVGRIGSLICFDLRFPEPGLLLSQPGPGSPWAGRP 182

Query: 164 AEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPF 218
           A++L  P+A+        HW TLL ARA++T  Y+VAA + G  N      GQS + DP+
Sbjct: 183 AQVLTYPSAFTL-RTGAAHWETLLRARAIETQSYVVAAAQVGRHNEKRASWGQSIVADPW 241

Query: 219 GVTI-----------------AAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G  +                 A    +  +   E+  + + +VR ++P+   RR
Sbjct: 242 GRVVLKLKGVVSDPKDVPEGTAEEGAVGEIGFVEIDIDGLERVRKEMPL--QRR 293


>UniRef50_Q15NS3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=13 Tax=Bacteria RepID=Q15NS3_PSEA6
          Length = 302

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 60/284 (21%), Positives = 104/284 (36%), Gaps = 24/284 (8%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEA--LLARDDHDADLSVKSA 57
           + V   Q AV  +  + + +  A  + + AE    L  L E    L     +       A
Sbjct: 11  LKVGVVQQAVANNDKQLSWQRSAEQVTKLAEQGCELVMLQELHSTLYFCQQENTDFFDLA 70

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG-NIVARYAKLHLYDA 116
           + + G         + +  +  I ++      G   N  V       +V +Y K+H+ D 
Sbjct: 71  EPIPGPATDYFSELAAKLDIVLITSLFEKRGSGLYHNTAVVFDRQLGMVGKYRKMHIPDD 130

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
               E      G+     ++    K+G++ C+D  +PE A   A++GA++L  P A    
Sbjct: 131 PGFYEKFYFTPGDMGFEPIQTSVGKLGVLVCWDQWYPEAARLMAMRGADMLFYPTAIGWD 190

Query: 177 PLKE--------HHWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRIIDP 217
           P             W T+  + A+  +  +V A   G +             GQS I  P
Sbjct: 191 PADTVDEQQRQFGAWQTIQRSHAVANSVPVVVANRTGFEASPVEGDNGIQFWGQSFIAGP 250

Query: 218 FGVTIAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            G  +A A  +    +M E+   R  QV+   P   +RR    +
Sbjct: 251 QGEILAQADADSEQNLMVELDLARTEQVKRIWPYFRDRRIDAYE 294


>UniRef50_C7LN61 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfomicrobium baculatum DSM 4028
           RepID=C7LN61_DESBD
          Length = 270

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 77/266 (28%), Positives = 125/266 (46%), Gaps = 14/266 (5%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +AA Q + +      N +  ++ +   A+    L   PE      D     S+  A  
Sbjct: 1   MKIAAVQLSGLPGDVSGNLDKISAAVQTGAKASCRLLLFPEISDLGYDMP---SIALAGR 57

Query: 60  LEGEFL-GRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF 117
                +  RL   ++ + +  +  + +P   G A N LVA    G+I+ARY K+HL+ A 
Sbjct: 58  DWWPRVRDRLMALAREHDICLVCGVCLPGPDGLA-NALVAFGPTGDILARYRKIHLFTAT 116

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E+     G+EI    + EG++ GL  CYDLRFPEL   QAL G + ++L +AW +  
Sbjct: 117 DADETEVFSPGSEIV-CFDFEGVRFGLSVCYDLRFPELYRVQALHGCQAMLLASAWPK-- 173

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALIM 233
            +   W TL AARAL+  C+++ A   G++      G+S  + P G    A+++   +I 
Sbjct: 174 RRIDIWQTLCAARALENQCFLLGANRIGDQGAFPFGGRSLFVTPGGEITLASADQEGVIT 233

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAPP 259
             V    +  +R  +P L +RR    
Sbjct: 234 GTVDLAELAAIRQNIPALAHRRPELY 259


>UniRef50_Q02J62 Putative N-carbamoylputrescine amidohydrolase n=4 Tax=Bacteria
           RepID=Q02J62_PSEAB
          Length = 303

 Score =  228 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 64/279 (22%), Positives = 108/279 (38%), Gaps = 20/279 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
           + +A  QFA +   + N +    L+ +AA   A L  L E               ++ A+
Sbjct: 4   LTLATTQFACSWSLDDNLDRAERLVREAAARGAQLVLLQELFATPYFCIEQDHRHLRLAE 63

Query: 59  LLEG-EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
              G   L R    ++   +   L+ +  +   R  ++ VA   G ++  Y K H+ +A 
Sbjct: 64  TFRGSRVLARFSSLARELGVVLPLSWYERAGNARFNSLAVADADGRLLGVYRKAHVPNAI 123

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
             QE      G+    + +    ++G+  C+D  FPE A   AL GAE+L+ P A    P
Sbjct: 124 GYQEKEYFSPGDSGFRVWDTAVGRIGVGICWDQWFPETARCLALLGAEVLLFPTAIGSEP 183

Query: 178 L-----KEHHWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRIIDPFGVT 221
                    HW      +A      +VAA   G +             G S I D  G  
Sbjct: 184 GAAQLDSRDHWQIAQRGQAAANLVPLVAANRIGREVACGDPALAMRFYGSSFIADHKGAL 243

Query: 222 IAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +AAA  +  A+++  +  + + + R    V  +RR    
Sbjct: 244 LAAAGRDEEAVLVCGLDLDAIGEERLAWGVYRDRRPELY 282


>UniRef50_Q2N7J4 Hydrolase n=5 Tax=Sphingomonadales RepID=Q2N7J4_ERYLH
          Length = 283

 Score =  227 bits (580), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 65/277 (23%), Positives = 109/277 (39%), Gaps = 19/277 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDD---HDADLSVKS 56
           + VAA Q  + +   + N +  A L+ QAA   A +   PE           D  L   +
Sbjct: 4   ITVAALQLPLGSEDEQANIDAVAELVEQAAARGAEIVLPPELFSGPYFCQVEDEALFALA 63

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD 115
              LE   +  +R+ + +  +  I T          +N L  +   G +   Y K H+ D
Sbjct: 64  RPTLEHPSVVAMRKLAGKLEIA-IPTSFFERDGHHYYNTLAMIGPDGELQGTYRKSHIPD 122

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +E      GN+   + +V G ++G+  C+D  +PE A   AL GAE+L  P A   
Sbjct: 123 GPGYEEKFYFRPGNDGFKVWDVCGTRIGVGVCWDQWYPECARVMALMGAELLFYPTAIGS 182

Query: 176 GPLKE-----HHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAAS 226
            P          W   +   ++     ++AA   G +      G S I + +G  I    
Sbjct: 183 EPYDADFDTSRMWQRSMQGHSVSNCMPVIAANRIGTEGEAKFYGHSFITNEWGDKIVEFG 242

Query: 227 -EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
            E   +++A +  +   + RA +    +RR   PQL 
Sbjct: 243 AEEDGVLVATLDLDEAAKHRAGMGFFRDRR---PQLY 276


>UniRef50_Q2RWF2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Rhodospirillaceae RepID=Q2RWF2_RHORT
          Length = 279

 Score =  227 bits (580), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 76/267 (28%), Positives = 122/267 (45%), Gaps = 14/267 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              A  Q         N E  ++L+ +A E  A +  +PE +   +    ++  K+    
Sbjct: 8   FTAACIQVNAGREVYPNVEAASALVREARERGADMVFMPENVAMMEWGRRNIQAKAMPEE 67

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPS-TPGRAWN-MLVALQAGNIVARYAKLHLYD--- 115
           +   L   R  ++   +         +   G   N   V    G I  RY K+H++D   
Sbjct: 68  DHVALTAFRDLARDLHIWLHCGTLAVAVGDGMVANRTYVVDSDGAIRGRYDKIHMFDVNL 127

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES    AG+    L ++   ++GL  CYDLRFP L  A A  G   L +PAA+
Sbjct: 128 ADGESYKESSTFQAGSRAVAL-DIPFGRLGLSICYDLRFPHLFRALAKAGCHYLTIPAAF 186

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEM 228
            R    E HW  L   RA++T CY+++  + G         G + IIDP+G  +A A E 
Sbjct: 187 TR-TTGEAHWHVLQRTRAIETGCYVISPAQTGTHAEGRQTYGHALIIDPWGRVLADAGEA 245

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRR 255
           P +I+A++ PE+V + RA +P L++ R
Sbjct: 246 PGIILAKIDPEKVVEARAMVPSLSHDR 272


>UniRef50_Q1QX75 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=44 Tax=Bacteria RepID=Q1QX75_CHRSD
          Length = 299

 Score =  227 bits (580), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 59/285 (20%), Positives = 101/285 (35%), Gaps = 26/285 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARD--DHDADLSVKSAQ 58
           + V   Q A      ++     + +   A   A+L  L E          + D     A+
Sbjct: 5   LKVGLVQQAAWPDKARSLAESEAGIRALAAQGATLVLLQELHATHYFCQTEDDTLFDLAE 64

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
            L+G    RL   +    +  + ++      G   N  V        V  Y K+H+ D  
Sbjct: 65  PLDGPSAQRLAALAAELDIVLVGSLFERRAAGLYHNTAVVFDRQQGRVGYYRKMHIPDDP 124

Query: 118 AIQESRRVDAGNE----IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
              E      G+         ++    ++GL+ C+D  +PE A   AL GA++L+ P A 
Sbjct: 125 GFYEKFYFTPGDAEADAGFEPIDTSVGRLGLLVCWDQWYPEAARLMALAGADLLLYPTAI 184

Query: 174 VRGPLKE--------HHWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRI 214
              P             W+ +  +  +     ++ A   G++             G S +
Sbjct: 185 GWTPTDAPEEKQRQKDAWTLIQRSHGVANGLPVLVANRVGHEPDPSGASPGIDFWGGSFV 244

Query: 215 IDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             P G  +A A + PA ++ +V   R  QVR   P L +RR    
Sbjct: 245 CGPQGELLAQADDAPAHLLVDVDLSRSEQVRRVWPYLRDRRIDAY 289


>UniRef50_D1NXA0 Hydrolase, carbon-nitrogen family n=8 Tax=Enterobacteriaceae
           RepID=D1NXA0_9ENTR
          Length = 277

 Score =  227 bits (579), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 18/273 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSA 57
           + VA  QF       ++N +  A L  QAA   A L   PE        D  ++     +
Sbjct: 6   VKVALAQFDSELGNKQRNLQRMAQLCEQAAAQGAKLICFPELATTGYRGDLLSNKLWDLS 65

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTP-GRAWNMLVALQAG--NIVARYAKLHLY 114
                E        + R  ++ +       +  G  +N +     G   I   + K+H +
Sbjct: 66  DSEGSETYCLFSELASRLNLSIVAGFAERGSYLGEVYNSVGLWNPGCKTISGVFRKVHAF 125

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                 E +    G+   P+ +    KVG+M CYD+ FPE+A    LQGAE+L+ P+AW 
Sbjct: 126 GI----EKQWFKNGDS-FPVFDTPIGKVGIMICYDMGFPEVARILTLQGAELLIAPSAWC 180

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAAS-EMP 229
                   W    A RAL+   +++A    G++      G S+++ P G  +  A+ +  
Sbjct: 181 V--QDRDMWDINTACRALENGTHLLAVNRWGSEEDLHLFGGSKVLGPRGQVLCEATCDGE 238

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           AL++ EV        R  +P L +R+     LL
Sbjct: 239 ALLIGEVDFRLQAHTRLSVPYLRDRKPQRYGLL 271


>UniRef50_A4SNH5 Amidohydrolase family protein n=2 Tax=Proteobacteria
           RepID=A4SNH5_AERS4
          Length = 284

 Score =  227 bits (579), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 67/269 (24%), Positives = 113/269 (42%), Gaps = 16/269 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q       + N     +L+ QAA   A    LPE        +      +A + 
Sbjct: 11  VRVAVLQMVSGDDLDHNLTQAEALLRQAAAEGAEFALLPEYFYLMPADERARVALAAPVS 70

Query: 61  EGEFLGRLRRESKRNMMTTILTI--HVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF 117
           +   L   +  ++   +  +          PG+  N  + +   G + +RY KLHL+   
Sbjct: 71  DHPLLAWAQGLARELGIWLLAGTLPLESDEPGKMHNSSLLIDPQGALASRYDKLHLFGFC 130

Query: 118 A----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                  E+  +  G E+     +    +    CYDLRFPEL         + + LPAA+
Sbjct: 131 TGQEQYDEAATMSPGREVVS-HPLPWGMLRFGICYDLRFPELFRL--DPAPDFIALPAAF 187

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEM 228
                   HW  LL ARA++   +++A+ + G+        G S IIDP+G  +A   E 
Sbjct: 188 TH-TTGLAHWELLLRARAVENLAFVLASAQGGHHPGGRRTFGHSMIIDPWGQVLARVEEG 246

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFA 257
             + +A +     R+VR+QLP L++R+ +
Sbjct: 247 HGMAIATLDLAAQRKVRSQLPALSHRKIS 275


>UniRef50_Q1QTM0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QTM0_CHRSD
          Length = 260

 Score =  227 bits (579), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 65/264 (24%), Positives = 104/264 (39%), Gaps = 14/264 (5%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +   Q   V      N    A    QA    A L  LPE  L+   +  +   + A+ 
Sbjct: 1   MKLMLAQTDPVCGDVAANLASLARQCQQAVAAGADLLVLPELALSGY-NIFERLEELAEP 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
           + G    R    +  + +  +  +      GR  N  V +   G  +A Y K  L+D   
Sbjct: 60  VGGPIAQRAAELAAEHELFLLFGLAERQADGRLTNSAVLIDDRGERIATYHKRQLWD--- 116

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +E     AG +   ++E    ++GLM CYD  FPE+A A A QGA++++ P A +    
Sbjct: 117 -REHAFFAAGED-CCVVETRLGRLGLMICYDNEFPEVARALATQGAQVILSPTANMVPNA 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
           +         ARALD  C++      G +      G S I  P G  +    +    ++ 
Sbjct: 175 ERQALQI--RARALDNQCFVACINRAGEEAELHYCGNSLIAGPDGEVLGRLGDAAGSLVV 232

Query: 235 EVTPERVRQVRAQLPVLNNRRFAP 258
           ++   R+   RA    L + R  P
Sbjct: 233 DIDLSRIDASRAHQDYLQDLRPMP 256


>UniRef50_C9D316 Hydrolase n=1 Tax=Silicibacter sp. TrichCH4B RepID=C9D316_9RHOB
          Length = 276

 Score =  226 bits (578), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 89/266 (33%), Positives = 127/266 (47%), Gaps = 13/266 (4%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
             AA Q   T+    N     +L+ +AA   A + +LPEA         +   +     E
Sbjct: 3   RFAAIQMCSTADVAANNAAIEALVREAAGQGARVISLPEAANILLRDQMEYPARCLPEAE 62

Query: 62  GEFLGRLRRESKRNMMTT-ILTIHVPSTPG-RAWNMLVALQA-GNIVARYAKLHLYD--- 115
              L   +  ++   +     ++ + +  G R WN    +   G I ARY KLH +D   
Sbjct: 63  DSTLALCQALAQELGVWLHTGSLLLRAEEGSRIWNRGHMISPTGAITARYDKLHTFDVAL 122

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
             A    ESR V  G   A   E +G+K+GL  CYDLRF  L  A A  GA +L++PA++
Sbjct: 123 GGAGDFIESRAVAPGQRGAITCEADGLKLGLSICYDLRFSYLFRALASAGASVLMIPASF 182

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMP 229
                   HW  LL ARA++T  Y+VAA + G ++     GQSRII P G  +AAA + P
Sbjct: 183 -SPITGPLHWEPLLKARAIETGSYVVAAAQSGTRDGLRTHGQSRIISPMGEVLAAAGDEP 241

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRR 255
            +I AE+    V + R +LPVL   R
Sbjct: 242 GVICAEIDLAEVTETRRRLPVLAQTR 267


>UniRef50_Q5UF08 Predicted amidohydrolase n=1 Tax=uncultured alpha proteobacterium
           EBAC2C11 RepID=Q5UF08_9PROT
          Length = 276

 Score =  226 bits (577), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 77/265 (29%), Positives = 117/265 (44%), Gaps = 16/265 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q+  +    K       L+A+AA   ASL ALPE           L  K+    
Sbjct: 2   LRVAALQYCASDDVAKTLHHIQPLIAEAASK-ASLVALPECANYLAASREQLFQKAEWDD 60

Query: 61  EGEFLGRLRRESKRNMMTTILT--IHVPSTPGRAWN-MLVALQAGNIVARYAKLHLYDAF 117
           E      L   ++   +  +    I       +  N  L+    G ++A Y K+H++DA 
Sbjct: 61  ESYSQKWLGNIAREFGIWLLAGSLIMRRRDNNQLANRSLLFGPDGEVIAYYDKIHMFDAD 120

Query: 118 A-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES    AG     +  ++ +  GL  CYD+RF  L    AL GA++ ++PAA
Sbjct: 121 VGDGKMYRESASFSAGQSPV-IAHIDNVPCGLTICYDVRFAHLYRQLALDGAQLFLVPAA 179

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           +     K  HW  LL ARA++T CY+VA  + G         G S II+P+G  IA A +
Sbjct: 180 FTALSGK-AHWHVLLRARAIETGCYIVAPAQSGTHADGRKTYGHSLIINPWGEIIAEAKD 238

Query: 228 MPALIMAEVTPERVRQVRAQLPVLN 252
             ++I A +      + R  +P L 
Sbjct: 239 GDSIIYAALDLSATARARNAIPSLK 263


>UniRef50_C0ZEK3 Beta-alanine synthase n=59 Tax=Bacteria RepID=C0ZEK3_BREBN
          Length = 296

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 64/265 (24%), Positives = 101/265 (38%), Gaps = 19/265 (7%)

Query: 14  WEKNAEICASLMAQAAENDASLFALPEALLARD---DHDADLSVKSAQLLEGEFLGRLRR 70
            EK  E    ++ +AA   A +  L E         +        + ++  G  +     
Sbjct: 26  KEKAIEKHERMVREAAAKGAQIICLQEIFYGPYFCAEQQPKWYESAEEVPNGPTVQHFSS 85

Query: 71  ESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLY------DAFAIQESR 123
            ++      IL ++     G  +N    +   G  + +Y K H+             E  
Sbjct: 86  LARELGTVLILPVYERVGIGTYYNTAAVIDADGTYLGKYRKQHIPHVGVGSSGCGFWEKY 145

Query: 124 RVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHW 183
               GN   P+ E    KVG+  CYD  FPE A    L GAEI+  P+A V G L E+ W
Sbjct: 146 YFKPGNLGYPVFETVFAKVGVYICYDRHFPEGARLLGLNGAEIVFNPSATVAG-LSEYLW 204

Query: 184 STLLAARALDTTCYMVAAGECGN-------KNIGQSRIIDPFGVTIAAAS-EMPALIMAE 235
                A A+    Y+ A    G        +  GQS ++DP G  +A  S +   +I+AE
Sbjct: 205 KLEQPAHAVANGYYVAAINRVGTEAPWNMGEFYGQSYLVDPRGQFVAMGSRDQDEVILAE 264

Query: 236 VTPERVRQVRAQLPVLNNRRFAPPQ 260
           +    + +VR       +RR    +
Sbjct: 265 MDRNTIHEVRDTWQFYRDRRPETYE 289


>UniRef50_B8D189 Nitrilase/cyanide hydratase n=1 Tax=Halothermothrix orenii H 168
           RepID=B8D189_HALOH
          Length = 273

 Score =  226 bits (576), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 65/267 (24%), Positives = 109/267 (40%), Gaps = 18/267 (6%)

Query: 3   VAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSAQL 59
           + A Q A   +  E N +   + +A+  +  A +   PE      D D   D     A+ 
Sbjct: 6   IGAVQMASKLADKEGNIKQALTYIAEYGDR-ADILIFPELFTTGYDLDIVGDDYYSLAEK 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQA-GNIVARYAKLHLYDA 116
           + G         ++      I  +           +N    +   G+   +Y K+H+Y A
Sbjct: 65  IPGRTTEIFSEYARMYKTAIIGNMVERDKNVGEILYNTTFVIDKKGDYTGKYRKVHVYPA 124

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
               E      G E  P+  V G+K+GL TCYD  F E+    A +GA+I+ +P+A  +G
Sbjct: 125 ----EFTYFKRGTE-FPVFNVNGVKIGLATCYDHGFGEMFRILARKGAQIIFIPSAIPKG 179

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALI 232
              E+       ARA D   + VA    G    +   G S +++P G  I  A +   + 
Sbjct: 180 Y--EYLLKLRTRARAQDNQLFTVAVNSAGKTPNSHFCGNSMVVNPRGEIIQEADDGEGVF 237

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +AE+  E + + R Q P++ +  F   
Sbjct: 238 LAELDLELIERERKQEPLIRDSAFDLY 264


>UniRef50_C7QZX4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Jonesia denitrificans DSM 20603
           RepID=C7QZX4_JONDD
          Length = 260

 Score =  225 bits (575), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 90/255 (35%), Positives = 126/255 (49%), Gaps = 4/255 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + V AGQ    +  E         +  A +    L  LPE   +       +   +A+ L
Sbjct: 7   LRVGAGQLMAAADHEVMRAQVRECLDDARDQGVDLLVLPEY--SHYYDPRGVPAHAAEPL 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +G F+  L R +    +T +  +  P+      N LV +  G + A Y K+HLYDAF  +
Sbjct: 65  DGPFVQLLARWTADASVTVVAGLTRPAHRHPV-NTLVVVAEGAVQATYDKVHLYDAFGYR 123

Query: 121 ESRRVDAGNEIAP-LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           ES  ++ G+     +  V    VGL TCYDLRFPEL   +   GA+I+V PAAWV GP K
Sbjct: 124 ESDHLEQGDVAQEGVFSVGEFSVGLQTCYDLRFPELTRRRIDAGADIVVNPAAWVAGPNK 183

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
            HHW TLLAARA++ T  MV A   G    G +RI+ P G T   A+    ++  EVT  
Sbjct: 184 LHHWRTLLAARAIENTVVMVGAALDGRGVCGDTRIVFPDGTTAVGAAHGRHVVSVEVTRT 243

Query: 240 RVRQVRAQLPVLNNR 254
            +   R + P L+NR
Sbjct: 244 LIADARERNPSLSNR 258


>UniRef50_D2RHR5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Archaeoglobus profundus DSM 5631
           RepID=D2RHR5_ARCPR
          Length = 231

 Score =  225 bits (575), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 60/252 (23%), Positives = 107/252 (42%), Gaps = 23/252 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +   Q  +    +KN      L+ +   + A +   PE      +      +++    
Sbjct: 1   MRIGLAQLRL-ENMDKNVRKALDLLRK---SKADVVVFPELFNTGYN------LENISKS 50

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           + +F   L   SK      I  I     P + +N  + +  G I+ R+ K  L+    + 
Sbjct: 51  DPKF---LIEASKETKAVIIAGI-----PEKGYNTALVIHRGKILGRHRKTKLFPL--LN 100

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           E +   AG ++   +E      G+M CY+LRFPE+A     +GA+IL + A +     + 
Sbjct: 101 EHKIFKAG-KVVKPIETPFGLFGIMICYELRFPEIARKLVNKGAKILFVIAQFPSE--RI 157

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
            HW  LL ARA++   ++V      +   G S ++DP G  +    +  A    ++  + 
Sbjct: 158 EHWKVLLRARAIENQVFVVGVNCVNDHCGGYSMVVDPLGNVLKELGDCEAYDEVDINIKY 217

Query: 241 VRQVRAQLPVLN 252
           V +VR + P LN
Sbjct: 218 VDEVRKKYPFLN 229


>UniRef50_C9N4S0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Streptomyces RepID=C9N4S0_9ACTO
          Length = 265

 Score =  225 bits (574), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 79/268 (29%), Positives = 114/268 (42%), Gaps = 15/268 (5%)

Query: 1   MLVAAGQFAVTSVWEKN--AEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M  +  Q AV      N   E  ASL+  AA+  A L  LPE        D     + A+
Sbjct: 1   MHASLIQMAVNPDESVNSRRERAASLV--AAQRGADLVLLPELW-PVGAFDYTAFAEEAE 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNM-LVALQAGNIVARYAKLHLYDA 116
            L+G     + + +    +          +  G  +N  LV    G   A Y K+H +  
Sbjct: 58  PLQGPTHRIMAKAAAEAGVWLHAGSFVERAEDGTLYNTSLVFSPEGERAAAYRKIHRF-G 116

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
           F   E+  + AG E+  +  +    +GL TCYDLRFPE        GAE LV+ A W   
Sbjct: 117 FDKGEAVLMGAGEELVTVA-LPETILGLATCYDLRFPEQFRGLVDAGAETLVVSAGWPER 175

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALI 232
             +  HW+ L  ARA++   Y++A G  G     +  G S ++DP+G  +A A     ++
Sbjct: 176 --RRSHWTLLAQARAVENQAYVLAVGSAGTHAGVEQAGHSIVVDPWGEVLAEAGAAEEVL 233

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
             E  P R    R Q P L +RR    Q
Sbjct: 234 TVEFDPARATTTREQFPALKDRRLGLAQ 261


>UniRef50_C1N8C1 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1N8C1_9CHLO
          Length = 361

 Score =  225 bits (574), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 65/298 (21%), Positives = 113/298 (37%), Gaps = 39/298 (13%)

Query: 1   MLVAAGQF-AVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + VA  Q    T+    N       +  AAE  A+L  LPE       +++  +      
Sbjct: 56  VKVALCQLACPTADKVANIARAREAIRNAAEGGAALVVLPEMWNCPYANESFPAHAETIG 115

Query: 60  LEGEF--LGRLRRESKRNMMTTILTIHVP-----------STPGRAWNML-VALQAGNIV 105
                  +  L   +  + +  +                       +N   V      ++
Sbjct: 116 ANDPTPSVTMLSEAAAAHDIVLVGGSIPERGVGVGGGGGADEEDVLYNACCVFDGKRGLI 175

Query: 106 ARYAKLHLYDA-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA 160
           AR+ K HL+D       + +ES  +  G E   +++    +VG+  C+D+RF E+A A A
Sbjct: 176 ARHRKTHLFDVDIPGEISFRESDTLTEG-EGLTVVDTAVGRVGVGICFDVRFGEMAAAMA 234

Query: 161 LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTT-----------CYMVAAGEC----- 204
            +GA++L+ P A+       HHW  L  ARA+D             C+++          
Sbjct: 235 NRGADVLIYPGAFNT-VTGPHHWELLQRARAVDNQARSIHWSPYDRCFVLTCSPARNTTG 293

Query: 205 -GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            G +  G S  + PF   +A   E P ++ A++    V + R  +P+   RR     L
Sbjct: 294 EGYQAWGHSTAVGPFAEVLATTDERPGIVFADLDLGEVTRRRRNMPLATQRRGDLYAL 351


>UniRef50_D1BL17 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Veillonellaceae RepID=D1BL17_VEIPT
          Length = 263

 Score =  225 bits (574), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 59/267 (22%), Positives = 108/267 (40%), Gaps = 14/267 (5%)

Query: 2   LVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            ++  Q  V  +  E N      L++QA      +  LPE          DL   +    
Sbjct: 4   RLSLIQMDVHVNEVEYNYARVQELLSQALSESPDIIVLPETWNTGFHPSKDLI--NISDR 61

Query: 61  EGEFLGRL-RRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFA 118
            GE    L    +K + +  +      +     +N   A  + G +V  Y+K+H +    
Sbjct: 62  NGERTKALLSTFAKEHNVNIVGGSVAVAKEDLVFNTSYAYNRKGTLVGEYSKMHGFSP-- 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +E +   +G       E++G+    + CYD+RFPEL    AL   E+L +PA W    +
Sbjct: 120 AKEDQYFASGTH-TTHFELDGIPCSTVICYDIRFPELVRMAALSNTELLFVPAQWP--TM 176

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMA 234
           +  HW  L   RA++   ++ A   CG     ++ G S + DP+G  +        +   
Sbjct: 177 RLRHWQVLNEVRAIENQLFLCAVNGCGTVGRVQSTGHSAVYDPWGTNLLEMDTREGISSI 236

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQL 261
           ++    V  +R ++ +  +R+    +L
Sbjct: 237 DIDLTVVEDIRNKINIFRDRKPELYKL 263


>UniRef50_A4J6K3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Desulfotomaculum RepID=A4J6K3_DESRM
          Length = 277

 Score =  225 bits (573), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 64/274 (23%), Positives = 113/274 (41%), Gaps = 22/274 (8%)

Query: 2   LVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            +A  Q   T    +KN       + +AA   A +   PE  +       ++     Q +
Sbjct: 5   KIALVQMQATFGNIDKNLSTLEKFINEAAAQQAEIICFPEMCIQGYSR--EIPDFLLQSI 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +GE +  L++ ++   +T I  +       R +   V ++ G  +  Y K HL       
Sbjct: 63  DGEAILFLKKLAQNKGITIIAGMAEKCLNKRPFITQVVIRPGQNIDYYRKTHL----GNS 118

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL-K 179
           E     AGNEI      E   +G+  C+D  FPE+    +L+GAE++  P A       +
Sbjct: 119 EQPYYQAGNEI-KTFSTEKTTIGIQICWDTHFPEMTTILSLRGAEVIFAPHASPTIVGDR 177

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASEM-PALIM 233
           +  W   LAARA D + ++ A    G+     +  G S +IDP G  +A   E   ++++
Sbjct: 178 KAIWLKYLAARAYDNSVFLAACNLVGDDGNGRQFCGGSMVIDPKGNVLAEDFEGKQSMLV 237

Query: 234 AEVTPERVRQVRAQLP-------VLNNRRFAPPQ 260
            ++   ++  +R +          L NRR    +
Sbjct: 238 VDLDCAQINAIRERKSSSMANSFFLANRRPEIYK 271


>UniRef50_C5BSY0 Hydrolase, carbon-nitrogen family n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BSY0_TERTT
          Length = 302

 Score =  225 bits (573), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 72/304 (23%), Positives = 117/304 (38%), Gaps = 55/304 (18%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
             V   Q        E N      L+ +A++ +  L  LPE LL           +  Q 
Sbjct: 5   FRVGLCQMVSQLEGVETNFSTLEGLLGRASKANCQLAVLPENLLTFGLKTRFTRDEQVQ- 63

Query: 60  LEGEFLGRLRRESKRNMMTTILTI--------------------------HVPSTPGRAW 93
               +L R    ++ + +  +                             H  S   + +
Sbjct: 64  ----WLVRFSALARAHKLWLVAGSMPLHGFSWADGDGDGDWEVSADTIRWHDASEDVKPF 119

Query: 94  NMLVALQA-GNIVARYAKLHLYDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMT 146
              V     G I + Y K+HL+DA       A +ES     G+ +  + E    ++G+  
Sbjct: 120 ATCVVFDDQGRIASAYRKMHLFDADVKDNTGAYRESDSFARGD-MPVVCETPWGRMGVGI 178

Query: 147 CYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN 206
           CYDLRFPE   A   QGA+ +VLP+A+     K  HW  LL ARA++    M+   + G 
Sbjct: 179 CYDLRFPEYFRALRQQGADFVVLPSAFTWATGKV-HWELLLRARAVENQIVMIGVNQGGE 237

Query: 207 K-----NIGQSRIIDPFGVTIAAASE---------MPALIMAEVTPERVRQVRAQLPVLN 252
                   G S +++ +G  IA A +            L++ +V  + +  +R  +PV N
Sbjct: 238 HTPQRKTWGDSMVVNGWGEIIARAGDDKLLEDSQLGEHLVVTQVDLDELELLRKDMPVWN 297

Query: 253 NRRF 256
           +RR 
Sbjct: 298 HRRL 301


>UniRef50_C5DKM8 KLTH0F05984p n=2 Tax=Saccharomycetaceae RepID=C5DKM8_LACTC
          Length = 352

 Score =  225 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 86/292 (29%), Positives = 140/292 (47%), Gaps = 40/292 (13%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARD---DHDADLSVKSAQ 58
            +A GQ   +S  ++N  +  +L+ QA  +DA +   PEA         H  +L+ KS  
Sbjct: 55  RIAIGQMCSSSSLDQNLGVVKTLIDQALASDAKVIFFPEAADYISRSASHSLELAEKSPA 114

Query: 59  LLEG--EFLGRLRRESKRNMMTTILTIHVPST-------PGRAWNMLVAL-QAGNIVARY 108
            +EG  + +  L  + ++  +   + +H+P+T         R  N L+ +   G I   Y
Sbjct: 115 FVEGLQKAIPELCSKHQKR-IDVSIGVHLPATSSDKSQHDTRLRNCLLYITHEGKIRQEY 173

Query: 109 AKLHLYDAFA-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQG 163
            KLHL+D        ++ES+ V  G  I  +L+    K+G   C+D+RFPELAL    +G
Sbjct: 174 QKLHLFDVEVPNGPILKESQAVQPGRAIPDVLDTPVGKLGSAICFDVRFPELALKLRSKG 233

Query: 164 AEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK---------------- 207
           AEIL  P+A+      E HW  L  ARALDT CY++  G+ G                  
Sbjct: 234 AEILCFPSAFTM-KTGEAHWQLLACARALDTQCYVIMPGQQGEHEVGIDPSKPGESPLKR 292

Query: 208 -NIGQSRIIDPFGVTIAAAS---EMPALIMAEVTPERVRQVRAQLPVLNNRR 255
            + G S ++ P+G  +AAA      P L++A++  +  +++R  +P+   RR
Sbjct: 293 VSWGHSMVVGPWGKVVAAADPANNEPQLLLADLDLDAQKKIRRDMPLWEQRR 344


>UniRef50_A1SE99 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=14 Tax=Actinomycetales RepID=A1SE99_NOCSJ
          Length = 280

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 68/275 (24%), Positives = 115/275 (41%), Gaps = 25/275 (9%)

Query: 1   MLVAAGQFAVTSV--WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           + VA  Q A           +  +  + +     A L  LPE   A     +     +A+
Sbjct: 12  LRVALLQVAYGDDESLSDRVQRVSQWIREV--GPADLVVLPELW-AHGGFASTTWRATAE 68

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGR---------AWNMLVALQAGNIVAR-Y 108
           L+ G  + ++   ++   +       +                WN  V +     V + Y
Sbjct: 69  LMNGPTIAQMASVAREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISPQGTVHKTY 128

Query: 109 AKLHLYDAFAIQESRRVDAGNEIAP---LLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
            K+H +  F   E R ++AG ++A    + +    +VG+ TCYDLRFPEL       GA+
Sbjct: 129 RKIHRF-GFGDGEPRVLEAGTDLAVAELVHDTGASRVGMATCYDLRFPELFRRLGDLGAD 187

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVT 221
           ++VLPAAW     +  HW  L  ARAL+   +++     G  +     G S+++ P G  
Sbjct: 188 VIVLPAAWPM--RRVEHWRLLGRARALENQAWVLQCNTAGTHSGLDMGGHSQVVAPTGEV 245

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           +A       +++ ++    V  VRA  PVL +RR 
Sbjct: 246 VAELGSDEDVLLTDIDLNLVASVRADFPVLADRRI 280


>UniRef50_C4R2Y9 Nit protein n=1 Tax=Pichia pastoris GS115 RepID=C4R2Y9_PICPG
          Length = 297

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 82/290 (28%), Positives = 125/290 (43%), Gaps = 36/290 (12%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +L+AAGQ    +    N    A L  +AA        LPEA      +            
Sbjct: 2   VLIAAGQMCSGADLAINGRAAARLAEKAAHMGCKALFLPEAADYVARNATHSKSLCMPSE 61

Query: 61  EGEFLGRLRRESKRNM-----MTTILTIHVPSTP--GRAWNMLVALQA-GNIVARYAKLH 112
              F+  L+ + +        +   + +H P+    GR  N L+ L + G+I  RY KLH
Sbjct: 62  SSPFVLTLQSKIRELKALGRPLCVCVGVHEPANDARGRVKNTLLWLNSHGDIAQRYQKLH 121

Query: 113 LYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           L+D       +++ES  V  G  + P       KVGL  CYD+RFPEL+L     GA++L
Sbjct: 122 LFDVALEDGRSLRESDSVQPGANLIPPFNSPVGKVGLAICYDIRFPELSLRLRALGAQLL 181

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN------------------I 209
             P+A+        HW  L  ARA+DT CY+V A + G                      
Sbjct: 182 AFPSAFTM-RTGAAHWELLGRARAVDTQCYVVMAAQAGRHGTGESVGLTGEAPALPRESY 240

Query: 210 GQSRIIDPFGVTIAAASE----MPALIMAEVTPERVRQVRAQLPVLNNRR 255
           G + I+DP+G  +A  S+       + +A++  +R+  VR  +P+   RR
Sbjct: 241 GHAMIVDPWGSILAQCSDVGRGTEDICIADIDLDRLDTVRRDMPLWEQRR 290


>UniRef50_A8IKB0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=13 Tax=cellular organisms RepID=A8IKB0_AZOC5
          Length = 584

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 62/267 (23%), Positives = 103/267 (38%), Gaps = 17/267 (6%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDD-HDADLSVKSAQ 58
           + VA  QF  T    E+N     +L  QAA   A L   PE         D        +
Sbjct: 5   ITVATVQFEPTLFEKERNITRLLALCEQAARAGAKLIVTPEMGTTGYCWFDRAEVAGQVE 64

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
            + G    R    ++ +    ++ +         +N  V +    +V  + K H Y    
Sbjct: 65  SVPGPTTERFAALAREHGCWIVIGMPEVDADDIYFNSAVLIGPDGVVGTHRKSHPY---- 120

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           I E +   AG+    + E    ++GL+ C D+ F E A   A+QGA+++   + W+    
Sbjct: 121 ISEPKWSAAGDLGHQVFETPIGRIGLLICMDIHFIETARLMAVQGADVICHISNWLAERT 180

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
              +W     +RA +  CY++ A   G +      G S +I+P G  +A         +A
Sbjct: 181 PAPYW----ISRAFENGCYVIEANRWGLERTVQFSGGSCVIEPDGSIVAVIDSGDGFALA 236

Query: 235 EVTPERVRQVRAQL--PVLNNRRFAPP 259
           ++   + R  R  L  PV   RR    
Sbjct: 237 QMDLAKAR-ARTVLGEPVFTQRRPELY 262



 Score =  152 bits (385), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 55/266 (20%), Positives = 90/266 (33%), Gaps = 36/266 (13%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQLL 60
            VA  QFA       N     +   QA  E  A L   PE  L+     A  ++ S    
Sbjct: 293 RVAVAQFAPGEGIADNLSRICAFAVQARTEEGADLVVFPELALSGLSDPAVRALSS---- 348

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +     RL   S R  +  ++     +  G  +N    L    +VA + KLHL       
Sbjct: 349 DDPAFMRLLNLSARLGLHMVVGFAERAADG-LYNSAALLGPEGLVAIHRKLHL----NAA 403

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA-------- 172
           +      G +   + +    ++GL+  +D  F E     AL+G +++  PAA        
Sbjct: 404 DRPWATPGAD-WTVADTSLGRIGLLIGHDATFCESGRILALRGCDLIACPAAIAGRFSYG 462

Query: 173 ---------WVRGPLKE-HHWSTLLAARALDTTCYMVAAGECGNK--NIGQSRIIDPF-- 218
                    W      + HHW      RA +   ++  A     +   +G S +  P   
Sbjct: 463 HGGSRVAQNWPIPTGADPHHWHHF-RVRAGENNVFLAFANVHAPEAGFMGLSGVFGPDTF 521

Query: 219 --GVTIAAASEMPALIMAEVTPERVR 242
               + A   E   L +A +    + 
Sbjct: 522 AFPRSEALLPEGEGLAVAIMDTSNLD 547


>UniRef50_Q8VYF5 N-carbamoylputrescine amidase n=162 Tax=cellular organisms
           RepID=AGUB_ARATH
          Length = 326

 Score =  224 bits (571), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 59/308 (19%), Positives = 108/308 (35%), Gaps = 48/308 (15%)

Query: 3   VAAGQFAVTSVWEKNAEICAS---------------------------LMAQAAENDASL 35
           V++ QFA +     N                                 L+ +A    A++
Sbjct: 12  VSSLQFACSDDISTNVAAAERFVSLSSSLPLSNYQSLPSSSSFKFPYALVREAHAKGANI 71

Query: 36  FALPEALLARD---DHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRA 92
             + E             D   ++        + R+++ +K   +   ++    +     
Sbjct: 72  ILIQELFEGYYFCQAQREDFFKRAKPYKNHPTIARMQKLAKELGVVIPVSFFEEANTAHY 131

Query: 93  WNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRF 152
            ++ +    G  +  Y K H+ D    QE    + G+    + + +  K+G+  C+D  F
Sbjct: 132 NSIAIIDADGTDLGIYRKSHIPDGPGYQEKFYFNPGDTGFKVFQTKFAKIGVAICWDQWF 191

Query: 153 PELALAQALQGAEILVLPAAWVRGPLK-----EHHWSTLLAARALDTTCYMVAAGECGNK 207
           PE A A  LQGAEIL  P A    P         HW  ++   A      +VA+   G +
Sbjct: 192 PEAARAMVLQGAEILFYPTAIGSEPQDQGLDSRDHWRRVMQGHAGANVVPLVASNRIGKE 251

Query: 208 ------------NIGQSRIIDPFGVTIAAASEM-PALIMAEVTPERVRQVRAQLPVLNNR 254
                         G S I  P G  +A A +   A+++A+   + ++  R    V  +R
Sbjct: 252 IIETEHGPSQITFYGTSFIAGPTGEIVAEADDKSEAVLVAQFDLDMIKSKRQSWGVFRDR 311

Query: 255 RFAPPQLL 262
           R    ++L
Sbjct: 312 RPDLYKVL 319


>UniRef50_A4BGL8 Predicted amidohydrolase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BGL8_9GAMM
          Length = 271

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 74/270 (27%), Positives = 110/270 (40%), Gaps = 17/270 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             V A Q   T     N       +A A   D  +  LPE        D        +  
Sbjct: 5   FTVCAVQMTSTDSLNDNLNWIDQQLANADLQDVQMLVLPETFALFGVKDQSALADQERAF 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML---VALQAGNIVARYAKLHLYDA- 116
           +G     +R+ +K   +  +       T           V    G +V  Y K+HL+DA 
Sbjct: 65  DGSVGQAVRQWAKGYQVWIVAGTVPVMTDEDRLPRARCHVVDADGELVGFYDKIHLFDAE 124

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                 A +ES     G+++  LL     ++GL  CYDLRFPEL  A   QGA+ + LP+
Sbjct: 125 VGDRQGAYRESDSYSGGDKVVTLL-TPWGRLGLSVCYDLRFPELFRALNDQGADFVTLPS 183

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS 226
           A+      E HW  L  ARA++    ++A  +CG+ +      G S I+D +G    +  
Sbjct: 184 AFTA-KTGEAHWEPLCRARAIENGYSLIAVNQCGDHDAKRSTWGHSMIVDAWGRV-ESIG 241

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             P L   ++ P   + +R  LPV  NRR 
Sbjct: 242 LDPGLAFFKLDPAADQVIRNTLPVNANRRL 271


>UniRef50_Q8TLM7 Carbon-nitrogen hydrolase n=2 Tax=Methanosarcina RepID=Q8TLM7_METAC
          Length = 309

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 70/314 (22%), Positives = 118/314 (37%), Gaps = 63/314 (20%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q  V     ++N E    +  +A +  A L   PE       +  +    +A+ 
Sbjct: 1   MKVACIQMDVLQCKKQENLEKALYMALKAVKKGAELIVFPEVFTTGFCY--EDLNHAAES 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTP------------------------------ 89
           L    L  L   S+ N    + +I    +                               
Sbjct: 59  LPSPTLENLACFSEANDCIILGSIIQKDSGEAYTEDDGEGSNDKGRDGGKKGSKKEEKGF 118

Query: 90  -GR------------------AWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNE 130
            G+                   +N+    ++G +   Y K H + A    E+     G+ 
Sbjct: 119 SGKETEIPGSKAFTERKNSTLYYNLGFCFESGVLAGTYLKTHPFKA----ENGYFSKGSS 174

Query: 131 IAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAA 189
           I P+ L+ + +K+GL  CY+LRFPE+A   ++ G+++LV  AA+     +  HW TL  A
Sbjct: 175 IEPISLKKQNLKIGLEICYELRFPEVARKLSIAGSDLLVTIAAFPNP--RAEHWKTLAKA 232

Query: 190 RALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVR 245
           RA++     +A    G+       G S IID +G   A A      I+ ++      ++R
Sbjct: 233 RAIENQIPHIACNRTGSVPDCTYFGNSMIIDAWGEIKAEAGSKECTIVCDLDLTGKEEIR 292

Query: 246 AQLPVLNNRRFAPP 259
             +PV  +RR    
Sbjct: 293 KAIPVFEDRRIELY 306


>UniRef50_Q6MPB5 Putative amidohydrolase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MPB5_BDEBA
          Length = 276

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 76/279 (27%), Positives = 122/279 (43%), Gaps = 33/279 (11%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDAS--LFALPEALLARDDHDADLSVKSAQ 58
           ++VAA Q         N      L+ +A  N A     + PE  L        L +K  +
Sbjct: 5   LVVAAVQMTSVDDVTTNLAQMEELLKEAF-NGAQPRFVSFPENCLY-------LRLKEGE 56

Query: 59  LLEG-----EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLH 112
            +EG         RL   +K       L        G  +N    +   G +   Y K+H
Sbjct: 57  KIEGLTLSHPAFARLSELAKHYNTYLHLGSIPLYLEGHLYNSSALITPEGEVQPTYQKMH 116

Query: 113 LYDA-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           L+D        ++ES     G     +++++G KVG   CYD+RF EL    A +  +++
Sbjct: 117 LFDIQLDGQAPLRESDVFRHGQT-PNVIDIDGWKVGEAICYDVRFAELFSQYARREVDVI 175

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN---------KNIGQSRIIDPF 218
           +LPAA++     E HW  LL ARA++   Y++AA + G          +  G S IIDP+
Sbjct: 176 LLPAAFLV-KTGEAHWEILLRARAIENQSYVIAAAQGGTHTGLRGGTRETYGHSLIIDPW 234

Query: 219 GVTIAAASEM-PALIMAEVTPERVRQVRAQLPVLNNRRF 256
           G  +    +  P + +++ T ER+  VR Q+P+  +RR 
Sbjct: 235 GAVVGQVEKRQPGVTISKFTRERIDSVRRQIPMKFHRRL 273


>UniRef50_B8FEV8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FEV8_DESAA
          Length = 266

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 71/259 (27%), Positives = 112/259 (43%), Gaps = 16/259 (6%)

Query: 2   LVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            +   QF V       N +     +   A+   +L  LPE      D+ A L   +AQ  
Sbjct: 5   KIGLVQFDVKLGNPRANIDHVRRAIQDLADQGVNLAVLPEMWSCGFDYSA-LKDHAAQTP 63

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
               L  L   ++   +    T+   +  G  +N    +   G++ A Y K+H +     
Sbjct: 64  --AVLDELCSLAENLNLAVSGTMPELTPDG-VYNTHYYINEKGSVQAEYRKVHRFTPAGE 120

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E    + G   + L      K GL+TCYDLRFPE + A  L GA +L++ A W    ++
Sbjct: 121 GE---FEPGAR-SVLAAAPWGKTGLLTCYDLRFPEQSRALVLAGAIVLIVSAQWPA--VR 174

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAE 235
             HW  LL ARA++   +++A   CG        G+S +I P+G  IA A     L+ A 
Sbjct: 175 IRHWDVLLQARAVENQAFVIACNRCGKDPELVYGGRSAVISPWGEVIAGAGGGETLLTAA 234

Query: 236 VTPERVRQVRAQLPVLNNR 254
           +    V+  R ++P L +R
Sbjct: 235 LNLYEVKDFRTRIPCLEHR 253


>UniRef50_B7Q2J6 Carbon-nitrogen hydrolase, putative n=1 Tax=Ixodes scapularis
           RepID=B7Q2J6_IXOSC
          Length = 399

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 70/240 (29%), Positives = 121/240 (50%), Gaps = 17/240 (7%)

Query: 35  LFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILT-IHVPSTP--GR 91
           +  LPEA+    +  A  + + A+ L+G  +   +  +KR  +   L  +H+       +
Sbjct: 1   MVFLPEAMDFLAEKKAQ-AYELAEPLDGPLIAEYKSLAKRLSVWLSLGSVHIKDADQGNK 59

Query: 92  AWNMLVALQA-GNIVARYAKLHLYD----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMT 146
             N  V + + GNIV  Y+K+H++D       I+ES    AG  I   +     KVGL  
Sbjct: 60  VSNTHVVINSEGNIVDTYSKVHMFDVDVPGARIRESDYTAAGTRITRPVATPVGKVGLGI 119

Query: 147 --CYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC 204
              +  +FPE +L+ A  GA+I+  P+A+   P    HW  ++ ARA+++ CY+V+A + 
Sbjct: 120 ISFHVGKFPEFSLSLAKMGADIITYPSAFTV-PTGMAHWEVIMRARAIESQCYVVSAAQV 178

Query: 205 GNKN-----IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           G  N      G + ++DP+G  +A  S+   + +AE+  + V +VR  +PV N+RR    
Sbjct: 179 GQHNPKRSSYGHALVVDPWGCVVAQCSDAVGIAVAEINLDSVAKVRQAIPVWNHRRTDLY 238


>UniRef50_D0XIR2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Alphaproteobacteria RepID=D0XIR2_9CAUL
          Length = 282

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 74/274 (27%), Positives = 119/274 (43%), Gaps = 19/274 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q    +  +        L+ QAA+  A L   PE     +       +      + 
Sbjct: 7   IALIQTRTPATAQAALAHVEPLIRQAADGGAKLILTPEGTNLLEQRRDRRGLAVTDEDQD 66

Query: 63  EFLGRLRRESKRNMMTTILTIHV----PSTPGRAWNMLVALQ-AGNIVARYAKLHLYD-- 115
             +  LR  +    +  ++   +     +   RA N  + +   G IVARY KLH++D  
Sbjct: 67  AAVIGLRHLAAELGVWLLIGSAIVKSGHAGDDRAANRSLLIDANGTIVARYDKLHVFDVD 126

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES  +  G+  A +      ++GL  CYD+RFP L    A  GA ++ +PAA
Sbjct: 127 LANGETYRESSTIRPGD-GACVAGTPWGRMGLTICYDVRFPHLFRQLARAGACMIAVPAA 185

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAAS- 226
           +   P  E HW TLL ARA++T  +++A  + G         G S ++ P+G  IA    
Sbjct: 186 FTV-PTGEAHWETLLRARAIETGAFVLAPAQGGTHEDGRRTWGHSIVVGPWGEVIAKLDH 244

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLN-NRRFAPP 259
           + P ++ A +    V   R  +P L  +R FAPP
Sbjct: 245 DEPGVLHATLDLAAVEAARTSVPQLRHDRDFAPP 278


>UniRef50_C0F0M8 Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM
           3353 RepID=C0F0M8_9FIRM
          Length = 273

 Score =  222 bits (567), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 64/273 (23%), Positives = 110/273 (40%), Gaps = 24/273 (8%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +   Q  ++    E N E       +A EN       PE  L     + + + + ++ 
Sbjct: 1   MRIGMAQMDISWENIEDNKEKVEQFFKKAEENQVDCLVFPEMTLTGFSMNVEETGEKSEN 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGR---------AWNMLVALQAGNIVARYAK 110
            +          SK+  + T+     P    R          +N L   + G +   YAK
Sbjct: 61  QK----HFFEEMSKKYKILTVFGYTEPVPEERLKEHPNWNHYYNRLGIAENGELKLNYAK 116

Query: 111 LHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
           +H +      E      G ++  + E +G  +G   CYDLRFPE+    + + +EI+ + 
Sbjct: 117 IHPFSYG--FEGEYYQGGRKLKSV-EWKGTTLGAFVCYDLRFPEIFQISSEK-SEIIFVI 172

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAAS 226
           A W +   +   W TLL ARA++   +MV     G        G S I  P G  +    
Sbjct: 173 ANWPKS--RIDQWDTLLKARAIENQVFMVGVNRTGEGDGLHYNGHSAIYSPNGEAVTTIR 230

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           E   L++ ++ PE ++++R   P+ N+RR    
Sbjct: 231 EEECLLIGDINPEEIKEMRKTFPMKNDRREELY 263


>UniRef50_A8ZSH3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfococcus oleovorans Hxd3 RepID=A8ZSH3_DESOH
          Length = 270

 Score =  222 bits (567), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 74/266 (27%), Positives = 116/266 (43%), Gaps = 14/266 (5%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           +     QF       E N +     +A  A   A L  LPE      D+   L+  +AQ 
Sbjct: 6   IRAGVVQFDTRLGDIEVNLKSALDGIAGLAAQGADLAVLPELWPCGFDN-RHLAAHAAQT 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
                L  +  ++  + M    ++      G    ++V  + G    RY K+HL+ A   
Sbjct: 65  P--RILEIVSAQAAEHSMVIAGSVPEAGPDGICNTLVVMDRDGREAGRYRKIHLFSAGG- 121

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E R    G +   + +    K+GLM CYDLRFPEL    AL GA  +++PA W     +
Sbjct: 122 -EERFFAKG-KAWAVCDTAAGKLGLMICYDLRFPELCRVLALDGAACVIVPAQWPEA--R 177

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAA-SEMPALIMA 234
             HW+ LL ARA++   ++V A  CG+       G S+++ P G  +A A ++ P +I+A
Sbjct: 178 IDHWNALLKARAIENQLFVVGANRCGHDPSLAYGGGSQVVSPTGEVLALARADAPQVILA 237

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
            +    +   R  +P L  R     Q
Sbjct: 238 NLDRAVMENFRKHIPCLQERAPESYQ 263


>UniRef50_C7QHA6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QHA6_CATAD
          Length = 264

 Score =  222 bits (567), Expect = 9e-57,   Method: Composition-based stats.
 Identities = 76/267 (28%), Positives = 114/267 (42%), Gaps = 15/267 (5%)

Query: 1   MLVAAGQFAVTSV--WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M V+  Q AV      E        L+    E  A L  LPE  +         +  +  
Sbjct: 1   MRVSLMQLAVDDAEAPEDRWTRVVKLVEAERETGAELVVLPELWVTGGFDYKSWTGHAEP 60

Query: 59  LLEGEFLGRLRRESKRNM----MTTILTIHVPSTP-GRAWNMLVALQAGNIVARYAKLHL 113
           + + + +  L +    +     M      +V  TP G  +N  V        A+Y K+H 
Sbjct: 61  IADSQPIAALEKVRTHDGSGPEMWLHFGSYVERTPEGILYNTAVFRGPDGKQAQYRKIHR 120

Query: 114 YDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
           +  F+  E   +  G +I  +       +GL TCYDLRFPEL      QG E +V+ +AW
Sbjct: 121 F-GFSEGEVTLMGPGKDIVTV-SSPWGTLGLATCYDLRFPELFRRLLNQGMEHMVMCSAW 178

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMP 229
                +  HW  LL ARA++   ++ A    G        G+S +IDP+G  +A A    
Sbjct: 179 PAK--RIEHWRVLLKARAIENQVFVFATNCVGTNGGVALGGRSAVIDPWGNVVAEAGTGE 236

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRF 256
            ++  +V P  V Q R+ LPVLN+RR 
Sbjct: 237 EVLRVDVDPALVAQTRSALPVLNDRRL 263


>UniRef50_Q97IH6 Predicted amidohydrolase n=1 Tax=Clostridium acetobutylicum
           RepID=Q97IH6_CLOAB
          Length = 260

 Score =  222 bits (567), Expect = 9e-57,   Method: Composition-based stats.
 Identities = 67/260 (25%), Positives = 113/260 (43%), Gaps = 16/260 (6%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A GQ  V     E+  E C + M +AA+  A L   PE  L       D   ++   
Sbjct: 1   MKIALGQIDVFFEDKERTKEKCLNFMKKAADKKADLIIFPEMTLTGFSMKVDKIGEN--- 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
            + E L   + +SK   + +       +  G+  N  +    G  + RY KLH +     
Sbjct: 58  -KFETLEWFKEKSKEFNIYSGFGFVEGTKKGK-NNFSICSPLGEEILRYTKLHPFSYG-- 113

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E +    GNEI    ++    +    CYDLRFPE+    A + +E +++ A W +  ++
Sbjct: 114 NEDKYFYKGNEIV-YCKIGDFNISTFICYDLRFPEIFQK-ASKESECILIIANWPK--VR 169

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAE 235
              W  L+ ARA++T  Y+ A    G        G S +++P+G   A  SE   L++ +
Sbjct: 170 REQWIALIKARAIETQSYIAAVNRVGEGDGLYYSGDSMVVNPYGEITAFKSEKEELLICD 229

Query: 236 VTPERVRQVRAQLPVLNNRR 255
           +    V++ R +     +RR
Sbjct: 230 ININEVKKCREEFRFKEDRR 249


>UniRef50_UPI000185C288 hydrolase n=1 Tax=Corynebacterium amycolatum SK46
           RepID=UPI000185C288
          Length = 280

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 85/281 (30%), Positives = 137/281 (48%), Gaps = 29/281 (10%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q  +++  E+N +   + +A+AA+ +A L   PEA +   +      V  A+  
Sbjct: 1   MRIALAQLELSASVEENLDAVKATIARAAQGNADLVVFPEATMKAFNSGRLDVV--AESS 58

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP--------GRAWNMLVA---LQAGNIVARYA 109
              F+  + + +    ++ ++ +  P+           R +N L+     + G  V  Y 
Sbjct: 59  SDRFVAEVSQAAHDAGISVVVGMFRPADQVERDGKTMHRVFNSLLLAWRDEDGPGVEFYD 118

Query: 110 KLHLYDAFAIQESRRVDAGNE----IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
           KLHL+DAF  +ES  V  GN       PL +   + +GL TC+D+RFPE  +  A  GAE
Sbjct: 119 KLHLFDAFGFRESDTVAPGNAHVVCDVPLADGSSVALGLATCFDIRFPEQFIQLANLGAE 178

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC------------GNKNIGQSR 213
           ++ LPA+W  GP K   W TL++ARALD+TC + A                G    G S 
Sbjct: 179 VIALPASWNDGPGKVLQWQTLVSARALDSTCVIAAVDAARPGGAKAAGKDEGPTGAGYSM 238

Query: 214 IIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
           +++  G  IA+A   P L++A+V    V ++R  +PVL  R
Sbjct: 239 LVNADGGVIASAGYGPQLLVADVDIAEVERIRRSIPVLEIR 279


>UniRef50_D2RK67 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Acidaminococcus fermentans DSM 20731
           RepID=D2RK67_ACIFE
          Length = 254

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 16/261 (6%)

Query: 1   MLVAAGQFAVTS--VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M V+  QF        + N       +    E+  SL  LPE       +  +      +
Sbjct: 1   MKVSVIQFERNEKYDVDANIAQMEQQIDLCKES--SLIVLPEMWATGY-YCFERYHHIEE 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF 117
               + +  L R++K           +     + +N L  +   G  +A Y K +L   F
Sbjct: 58  --NNKIIDFLCRKAKETGAYIAGGTIIEKIEDQYYNSLPFISPEGKCIATYRKRNLV-TF 114

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
             +E + +  G E + +++    ++G   CYD+RFP+  +    +  +I+VL AAW    
Sbjct: 115 NSEEVKLIQNGKE-STVVDTPFGRIGFAICYDVRFPKNFIEMTEKNVDIIVLSAAW--SF 171

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIM 233
            +  HW  L   RA++   Y++A    G +      G S I DP+G  IAAA     ++ 
Sbjct: 172 PRLEHWCLLSQCRAIENVSYLLACNCVGTERGNVYFGHSAIYDPWGTKIAAAGIEKTIVS 231

Query: 234 AEVTPERVRQVRAQLPVLNNR 254
           AE+ PE V+++R + PVL +R
Sbjct: 232 AEINPEHVQEIRKKFPVLRDR 252


>UniRef50_Q220F6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Burkholderiales RepID=Q220F6_RHOFD
          Length = 270

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 85/269 (31%), Positives = 130/269 (48%), Gaps = 20/269 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +AA Q    +  ++N +I   L+AQAA   A L  LPE      +HD D         
Sbjct: 1   MKIAAIQMVSGANLQRNLDIAGQLLAQAAAQGAELAVLPEYFCLMGEHDTDKLKIQETCG 60

Query: 61  EGEFLGRLRRESKRNMMTTILTI--HVPSTPGRAWNMLVALQA-GNIVARYAKLHLY--- 114
            G     L R ++   +  +        +   R  N  +   A G  VARY K+HL+   
Sbjct: 61  SGPIQDFLSRCARDLGLWIVGGTLPISTTAAERVRNSSLVFDATGQCVARYDKIHLFRFD 120

Query: 115 -DAFAIQESRRVDAGNEIAPL----LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
                  E+R ++AG +         +    ++GL  CYDLRFPEL    A   A++L++
Sbjct: 121 NGVECYDEARVLEAGTQAVTFDLASCDGNTYRIGLSICYDLRFPELYRQLA---ADVLLV 177

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAA 224
           P+A+      + HW  LL ARA++   Y++AA + G  +      G S +IDP+G  +A 
Sbjct: 178 PSAFTF-TTGQTHWEVLLRARAIENLAYVIAAAQGGVHDNRRRTWGHSMMIDPWGQILAQ 236

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNN 253
            +  PA+I+AEVT E ++  RA+LP LN+
Sbjct: 237 QAGGPAVIVAEVTQEFLQSARARLPALNH 265


>UniRef50_B0X5I4 Hydrolase n=5 Tax=Culicidae RepID=B0X5I4_CULQU
          Length = 279

 Score =  221 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 65/275 (23%), Positives = 113/275 (41%), Gaps = 17/275 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q       +       + +  AA    A L  LPE       + AD   +SA+ 
Sbjct: 6   IKIALLQLDSFPTKQAAISNALTQIRSAAKAKGAKLVILPECW--NSTYSADEFERSAEK 63

Query: 60  LEG-EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA- 116
           + G E    L   +K   +  +   +     G+  N        G  + +Y K+HL+D  
Sbjct: 64  IPGGETSVALANTAKELGIWLVGGTYPEVDAGKIHNTCAVFGPQGEFIGKYRKMHLFDMD 123

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                   ES  +  G E      VEG+ VG+  CYD RFPE A      G + L+ P+A
Sbjct: 124 IPGICTFSESSVLTPGKEFLT-FSVEGLNVGIGICYDQRFPEFAAIHRQLGTDFLIFPSA 182

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +        H+  +  ARALD + ++       + +      G S + DP+G  +  A E
Sbjct: 183 FDT-YTGPMHFELIARARALDNSMFVALCAPARDTSKDYVAYGYSTLCDPWGRVVCRAGE 241

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
            P +++ ++    +  ++ ++PVL  +R    +L+
Sbjct: 242 HPEMLVVDLDLTLLEDIKKKIPVLKQKRNDVYELV 276


>UniRef50_P55176 UPF0012 hydrolase in pqqF 5'region n=22 Tax=Bacteria
           RepID=YPQQ_PSEFL
          Length = 285

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 72/265 (27%), Positives = 116/265 (43%), Gaps = 13/265 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q          N +    +  +A   DA L  LPE  L+  +   +     A+ 
Sbjct: 22  MRVALYQCPPRPLDVAGNLQRLHQVAMEAT--DADLLVLPEMFLSGYNIGLEAVGALAEA 79

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            +G    R+   ++      +      S  G+ +N +  + A G  +  Y K HL+    
Sbjct: 80  QDGPSAQRIAAIAQAAGTAILYGYPERSVDGQIYNAVQLIDAQGQRLCNYRKTHLFGDL- 138

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             +     AG +  PL+E++G K+G + CYD+ FPE A   AL GAE++++P A +    
Sbjct: 139 --DHSMFSAGEDDFPLVELDGWKLGFLICYDIEFPENARRLALAGAELILVPTANMIPY- 195

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
            +      + ARA +  CY+  A  CG++      GQS I  P G  IA A    ALI+ 
Sbjct: 196 -DFVADVTIRARAFENQCYVAYANYCGHEEQIRYCGQSSIAAPDGSRIALAGLDEALIIG 254

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
            +  + + + RA    L++RR    
Sbjct: 255 TLDRQLMGESRALNRYLSDRRPELY 279


>UniRef50_B4D6H9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D6H9_9BACT
          Length = 260

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 75/255 (29%), Positives = 113/255 (44%), Gaps = 14/255 (5%)

Query: 5   AGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGE 63
           A Q  +       N     +L+  AA    SL  LPE        +  ++ + A+  +  
Sbjct: 8   AVQLDIVWEDKAANFRKVEALVDAAAPAPGSLVVLPEMFSCGFSMNLAVTRQGAEREDEA 67

Query: 64  FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQES 122
           F+  L   ++++ +     +          N  V     G +VARY K+H +      ES
Sbjct: 68  FIAAL---ARKHGVFITGGVVSRGAGEMGRNDAVVFSPEGKLVARYTKIHPFSGGG--ES 122

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
           +  +AG+EI    E  G  V    CYDLRFPE+  A A +GA + V+ A W     ++ H
Sbjct: 123 QGHEAGSEIVT-FEWGGFVVAPFVCYDLRFPEIFRAAARKGANLFVVMALWPVK--RQQH 179

Query: 183 WSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           W TLL ARA++   Y V     G +      G+S ++DP GV IA A E   ++ A + P
Sbjct: 180 WLTLLQARAIENQAYAVGVNRVGREPELLYAGRSVVVDPHGVIIADAGEREHILPATLEP 239

Query: 239 ERVRQVRAQLPVLNN 253
           E V   R   P L +
Sbjct: 240 EVVHSWRRDFPALRD 254


>UniRef50_C8RSM4 Carbon-nitrogen hydrolase n=3 Tax=Corynebacterium
           RepID=C8RSM4_CORJE
          Length = 320

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 84/287 (29%), Positives = 120/287 (41%), Gaps = 39/287 (13%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q       E N       +A  A N A L   PEA +   D+    +V  AQ L
Sbjct: 16  MRIAVIQMKAEPDVEANLARILKYIASGAANGADLVVFPEAAMFPFDNGRLDTV--AQPL 73

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP-----------------------GRAWNMLV 97
           +G F   +   +K++  T ++ +  P+                          R  N L+
Sbjct: 74  DGPFAQAIIDTAKKHGTTAVVGMFTPADTVYRTPSGQLVEEQPSDSPEANQFRRVNNTLL 133

Query: 98  ALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELAL 157
                + V  Y K+H YDAF  +ES  V  G     +         L TCYD+RFP   +
Sbjct: 134 VAGP-DYVTHYDKIHTYDAFGYRESDTVKPGKRRVVIDVGGVGVG-LATCYDIRFPGHFV 191

Query: 158 AQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC------------G 205
           A A  GA+++V+P++W  GP K   W  L AARALD+  Y++AAG              G
Sbjct: 192 AMAAAGAKVMVVPSSWADGPGKLEQWRELTAARALDSASYLIAAGMARPGSPERYGTADG 251

Query: 206 NKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLN 252
              IG S  I P G  +A       ++  ++ P  V +VR  LPVL 
Sbjct: 252 PTGIGHSVAIGPNGARLAETGYAAQVLTIDIDPNYVDKVRKTLPVLE 298


>UniRef50_C9XNA8 Putative carbon-nitrogen hydrolase n=6 Tax=Clostridium difficile
           RepID=C9XNA8_CLODC
          Length = 268

 Score =  221 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 62/266 (23%), Positives = 118/266 (44%), Gaps = 18/266 (6%)

Query: 1   MLVAAGQ-FAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +   Q  +V    +KN E    ++    ++ A +  LPE      + ++   VK+ +L
Sbjct: 5   VKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKHGADIICLPELFATGYNLESLGGVKTLEL 64

Query: 60  L--EGEFLGR-LRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLY 114
           +    +++   +   +KRN +  I     +       +N  V     G I+  Y K HL+
Sbjct: 65  IREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVYNSAVIFDRKGKIMGEYCKNHLW 124

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                 E+     G E   + + +  + G+M CYD  FPE++    L+G+EI+ +P+AW 
Sbjct: 125 SL----EAVYFK-GGEKVEVYDADFGRFGVMICYDAGFPEVSRELTLKGSEIIFIPSAWR 179

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASE-MP 229
                E  W   ++ RAL+ T Y V      N +     G+S+I +P G  I        
Sbjct: 180 I--QDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGKSKICNPRGTVITQLDTYRE 237

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRR 255
             +++E+  + +++ R  +P L +R+
Sbjct: 238 KYVLSEIDLDEIKKYREDIPYLKDRK 263


>UniRef50_A8PU96 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8PU96_MALGO
          Length = 330

 Score =  221 bits (563), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 73/315 (23%), Positives = 112/315 (35%), Gaps = 62/315 (19%)

Query: 3   VAAGQF-AVTSVWEKNAEICASLMAQA---AEND-ASLFALPEALLARDDHDADLSVKSA 57
           +A  Q   +      N     S++ +A   A N    +  LPE       +  D   K A
Sbjct: 14  IALIQLGRIGPDKMANLRHARSMVVEANKSAPNGRVDMIMLPECF--NSPYSVDQFPKYA 71

Query: 58  QLLEG-----------------------------------------EFLGRLRRESKRNM 76
           +   G                                           L  L   +K   
Sbjct: 72  ESFSGIYEQIKQGGRTSTSRGSRSWPVDNLNNERPLTLTSDFFQKSPTLEMLCNVAKETG 131

Query: 77  MTTILTIHVP--STPGRAWNM-LVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAG 128
              +           GR +N   V    G +++ + KLHL+D         QES  + AG
Sbjct: 132 TVLVGGSVPEWDEKTGRLYNTSCVLDAQGRLISLHRKLHLFDIDIPGKMTFQESLTLTAG 191

Query: 129 NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLA 188
           + +  + + +  +  L  CYDLRFPE A   +  GA  ++ P A+         W  LL 
Sbjct: 192 DRLT-IFDCDLGRFALGICYDLRFPESAQIASRLGASTILYPGAFNT-TTGPVAWELLLR 249

Query: 189 ARALDTTCYMVAAGEC----GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQV 244
           ARA+D   Y +         G    G S ++DP G  I+   E   ++ A + PER+ +V
Sbjct: 250 ARAIDNQVYTIGCSPARPPAGYPAWGHSTVVDPLGQVISTCDEKETVVYATLHPERIAEV 309

Query: 245 RAQLPVLNNRRFAPP 259
           R  +PV + RRF   
Sbjct: 310 RKTVPVSSQRRFDVY 324


>UniRef50_A7I641 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Candidatus Methanoregula boonei 6A8
           RepID=A7I641_METB6
          Length = 265

 Score =  220 bits (561), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 74/261 (28%), Positives = 119/261 (45%), Gaps = 15/261 (5%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M   + Q + V    ++  E   +   +AA   A+L + PE      D     S K+   
Sbjct: 1   MRCCSAQISGVWEAPDETLEQVETCFFRAAREGAALISFPEQFATGWD---PCSTKNTGG 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
           + G  +  LR  +K++ +  I +      P +  N  +A+   G I+  YAK+HL+    
Sbjct: 58  ISGTVVNGLRELAKKHKIAVIGSFRETCLP-KPRNTAIAIDRNGTILTTYAKIHLFTPG- 115

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +E +    G  +A    +EG+++GL  CYDLRFPE+      +G   +++PAAW +  L
Sbjct: 116 -REDQAFSPGTGLAT-FALEGVQIGLAICYDLRFPEIFRLYRQRGVHAVIVPAAWPKSRL 173

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMA 234
           K  HW   + +RA +   Y+      G    ++  G S   DP G  IA A     L+  
Sbjct: 174 K--HWELFIQSRAAENQMYIAGVNTSGTNPVDQYAGASMTADPHGTIIARAGTEQELLYY 231

Query: 235 EVTPERVRQVRAQLPVLNNRR 255
           E+ P  V Q R   PV N+R+
Sbjct: 232 EIDPLIVEQARRDFPVENDRK 252


>UniRef50_A6UC57 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Rhizobiaceae RepID=A6UC57_SINMW
          Length = 258

 Score =  219 bits (559), Expect = 8e-56,   Method: Composition-based stats.
 Identities = 64/259 (24%), Positives = 99/259 (38%), Gaps = 11/259 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q   T      N          A+   A+L   PE  +       +  V+ A+ 
Sbjct: 1   MKLAVLQMKSTGGDVAANLARIGRAAIDASGKGATLLVAPELAITGYGAG-EAIVELAEP 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
            +G  +  LRR S++     I       +    +N  V +        Y K HLY  +  
Sbjct: 60  PDGPIVQELRRISRQTGTAIIAG-FAEQSGHTVYNSAVHVDGDTAPTVYRKSHLYGDY-- 116

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E            L E  G+  G++ CYD+ FPE     AL GA+ +++P A   G   
Sbjct: 117 -ERSLFSPAEPSTRLFEHRGVTCGMLICYDVEFPENVRRLALAGADAVLVPTALPAGWSG 175

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAAS-EMPALIMA 234
                 ++  RA +   ++  A  CG+       G SRI  P G  +A +      LI A
Sbjct: 176 TFIAEHMIQTRAFENQVFVAYANHCGSDDMFSFAGMSRIASPDGQVMAKSGSTDETLIFA 235

Query: 235 EVTPERVRQVRAQLPVLNN 253
           E+ P+     RA+   LN+
Sbjct: 236 EIDPQAFAISRAENTYLND 254


>UniRef50_Q46E33 Carbon-nitrogen hydrolase n=3 Tax=Methanosarcina RepID=Q46E33_METBF
          Length = 266

 Score =  219 bits (558), Expect = 8e-56,   Method: Composition-based stats.
 Identities = 65/277 (23%), Positives = 123/277 (44%), Gaps = 26/277 (9%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M  A  Q  ++    ++N E   SL  +A   +A + A PE       +  D  V+ A+ 
Sbjct: 1   MKAACIQMNISLCSKKENLERALSLAEEAVSKEAEVLAFPEVFSTGFCY--DHIVELAET 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRA---------WNMLVALQAGNIVARYAK 110
             G  +G L   SK N      ++                  +N+   +++G +V  + K
Sbjct: 59  ASGPTIGALCDFSKENECILAGSMIEHREGSEFSSEMNIPPQFNLGFCIESGKLVGIHRK 118

Query: 111 LHLYDAFAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
             LY      E      G +I P+ L+   + +GLM C ++R+PE++   AL+GA++LV 
Sbjct: 119 TQLYGL----EKEYFALGEDIHPIRLKKYDLSMGLMVCNEIRYPEVSRKLALEGADLLV- 173

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAA 225
            +A        + W  +  +RA++     +A    GN       G+S I D +G  +A A
Sbjct: 174 -SASDMPDFYIYPWRIMSLSRAIENQLPHIACNRAGNDRFSTYPGRSFIADGWGRILAEA 232

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
            +   +++ E+  E+++++R    ++ +RR   P++ 
Sbjct: 233 GKEECVLIGEIDLEKIKEIRKTGSIIEDRR---PEIY 266


>UniRef50_Q28TG7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Jannaschia sp. CCS1 RepID=Q28TG7_JANSC
          Length = 298

 Score =  219 bits (558), Expect = 8e-56,   Method: Composition-based stats.
 Identities = 80/268 (29%), Positives = 123/268 (45%), Gaps = 15/268 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + V+  Q   T+    N         QAA+ +A + ALPEA    D        +     
Sbjct: 5   LRVSMVQMTSTNSHSDNVRSLRQAAQQAADQNADMLALPEAAGLMDRDKDHARAQITGEG 64

Query: 61  EGEFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWN-MLVALQAGNIVARYAKLHLYDAF- 117
              ++   R E+ R+ +     +  V +  GR  N  ++   +G+IVARY K+HL+D F 
Sbjct: 65  GDPYITACREEAARHGIWVHSGSCPVKAPDGRYLNHTVLVAPSGDIVARYDKIHLFDVFL 124

Query: 118 ----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               A  ES R   G+E A + +     + L  CYDLRFP L    AL G+ ++ +P+A+
Sbjct: 125 DGRRATGESDRYAPGSE-AVVADTPFGPMALSICYDLRFPHLYRDYALAGSTVMFIPSAF 183

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAA-ASE 227
              P    HW  LL ARA++   Y++AA + G+        G S I+ P+G  +A    +
Sbjct: 184 TV-PTGRAHWEVLLRARAIENGAYVIAAAQVGHHADGRVTWGHSLIVSPWGDVLADLGGD 242

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
            P  I  ++    V   R Q+P L N R
Sbjct: 243 APGQITLDLPLGDVVAARRQIPNLQNAR 270


>UniRef50_A5TTZ3 Possible amidohydrolase n=4 Tax=Fusobacterium RepID=A5TTZ3_FUSNP
          Length = 274

 Score =  219 bits (558), Expect = 9e-56,   Method: Composition-based stats.
 Identities = 60/259 (23%), Positives = 120/259 (46%), Gaps = 13/259 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
             +A  Q  +     EKN +     + +AA+ +  +   PE          D      + 
Sbjct: 9   FKIALAQIKIEQKNIEKNCKKIFERIEEAAKENVDIICFPELATIGYTITTDELQNLPED 68

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGR---AWNMLVALQA-GNIVARYAKLHLYD 115
               F+ +L+ ++K   +  ++      T  +    +N  + +   G I+A   K++L+ 
Sbjct: 69  FNNTFIEKLQEKAKLFKIHILVGYLESKTTKKSKDFYNSCIFIDDEGKILANARKVYLWK 128

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +E  +  AG++   + + +  K+G++ CYDL F E A  + L+GAEI+ +P+ W  
Sbjct: 129 ----KEKTKFKAGDK-FIVKDTKFGKIGILICYDLEFFEPARIECLKGAEIIFVPSLWSL 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAA-SEMPALIMA 234
               E+ W   LAA +L    +MV     G+   G+S+I++P G T+  A      L++A
Sbjct: 184 N--AENRWHIDLAANSLFNLLFMVGCNAVGDSCCGKSKIVEPNGSTLIEASGTKEELLLA 241

Query: 235 EVTPERVRQVRAQLPVLNN 253
            +   ++ ++R ++P L++
Sbjct: 242 TIDLAKLDEIRNKIPYLSD 260


>UniRef50_B7CB92 Putative uncharacterized protein n=1 Tax=Eubacterium biforme DSM
           3989 RepID=B7CB92_9FIRM
          Length = 262

 Score =  218 bits (557), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 64/264 (24%), Positives = 111/264 (42%), Gaps = 24/264 (9%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLG 66
           Q +V+   ++N     ++       D  +  LPE       +DA   +K+A L   E L 
Sbjct: 3   QMSVSMDNQQNIAKLKNI------PDCDILVLPEMWNCPYHNDA---LKTAYLRHDESLE 53

Query: 67  RLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF---AIQES 122
            L+  ++ N +  +      +     +N    L   G+IV  Y K HL++        E+
Sbjct: 54  ALKETARTNKIWIVAGSICTNK----YNRCYILNSDGDIVCSYDKTHLFEFHNKQDYCEN 109

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
                GN +    +    K G++ CYD+RFPE++   A  GA+IL  PAA+     K+ H
Sbjct: 110 EVFVPGNHL-QCFDTPWGKCGILLCYDIRFPEVSRILAQNGAQILFCPAAFNEQATKK-H 167

Query: 183 WSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVT 237
           W      RAL+   ++              + G S ++D FG  +    E  A  + ++ 
Sbjct: 168 WKLFTQTRALENEVFLCGVAPAKYTYKNYTSGGHSILVDGFGNIVVELGEEEACKVVDIH 227

Query: 238 PERVRQVRAQLPVLNNRRFAPPQL 261
            + + +VR ++P    RR    +L
Sbjct: 228 LKDIEKVRKRMPYWKVRRNDLYEL 251


>UniRef50_UPI0001973219 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Clostridium sp. M62/1 RepID=UPI0001973219
          Length = 262

 Score =  218 bits (556), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 64/272 (23%), Positives = 114/272 (41%), Gaps = 21/272 (7%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q  +     ++N E    L  +A      +  LPE              K+ + 
Sbjct: 1   MRVAMIQMDMELGRPDENFEKAVRLTEEACAARPDVITLPETWNVGF-----FPRKNLEE 55

Query: 60  LEGEFLGRLRR----ESKRNMMTTILT-IHVPSTPGRAWNML-VALQAGNIVARYAKLHL 113
           L      R+R      ++++ +  I   +      G  +N   V  + G + A+Y K+HL
Sbjct: 56  LSDRDCSRVRENFSMLARQHAVNIIAGTVANRKPDGGIYNTACVFDRKGELTAQYDKVHL 115

Query: 114 YDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
           +      E      G+      E++G+   L  CYD+RFPEL  ++ L G+++  + A W
Sbjct: 116 FSPSG--EHEFFRCGDRPCN-FELDGIPCSLAVCYDIRFPELIRSEMLAGSKVQFVVAQW 172

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMP 229
                +  HW TL  ARA+++  Y+      G     +  G S +  P G  +    E  
Sbjct: 173 PEA--RRLHWDTLNRARAIESQSYVCCTNSVGTAGEVRCAGHSAVYGPMGECLILGGEKE 230

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            +++A++    V +VR+ + V ++RR    +L
Sbjct: 231 QILVADLELSEVDRVRSSINVYHDRRPEAYRL 262


>UniRef50_C5L8W7 Putative uncharacterized protein n=2 Tax=Perkinsus marinus ATCC
           50983 RepID=C5L8W7_9ALVE
          Length = 300

 Score =  218 bits (556), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 60/280 (21%), Positives = 101/280 (36%), Gaps = 22/280 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAE-NDASLFALPEALLARDDHDADLSVKSAQL 59
           + VA  Q  V      +       +  A + +   L  + E                   
Sbjct: 12  LRVAVLQTKVFPEKASSLRGARETLLAAIDISKPDLCVIGEMFTCPYHPKYFRQYGERLP 71

Query: 60  LEGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-- 115
            +   L  ++  +K   +  I   +       + +N  + + + G +V  Y K HL+D  
Sbjct: 72  DQSPTLDMVKEVAKEKNVWIIGGTVPELDDADKVYNTALVVNSSGELVKTYRKAHLFDID 131

Query: 116 --------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI- 166
                        ES  +  GN    + +      GL  CYD+RFPE A        ++ 
Sbjct: 132 VPADGDKPGIRFFESETLSPGNSGPCVFDTPWGPFGLGICYDVRFPEYAALLRNIAPDLK 191

Query: 167 -LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN------IGQSRIIDPFG 219
            L+ P A+        HW  L  ARALDT CY+V A    ++N       G S +++P+G
Sbjct: 192 MLIYPGAFNM-TTGPAHWRLLGRARALDTQCYVVMASPSRSENPEDYQAWGHSMVVNPWG 250

Query: 220 VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             +    E       +V    V +VR  +P  + +R+   
Sbjct: 251 EVVDETDEKHGWFTVDVDLTMVDRVRRNIPTASQKRYDLY 290


>UniRef50_A8SQH9 Putative uncharacterized protein n=1 Tax=Coprococcus eutactus ATCC
           27759 RepID=A8SQH9_9FIRM
          Length = 314

 Score =  218 bits (556), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 66/274 (24%), Positives = 112/274 (40%), Gaps = 19/274 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSA 57
              AA          + N +  A    +A+   A     PE            +   + +
Sbjct: 42  FKAAAVNMDCELGNVKANLKKMADFCKEASTKGALAICFPELATTGYSPTILGEKYYEIS 101

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPST-PGRAWNMLVALQA-GNIVARYAKLHLYD 115
           + + G     L + +K   +  +  I   S  PGR +N  +A+   G IV+ Y K+H++ 
Sbjct: 102 EPIPGPSTNYLCKVAKATGLYIVTGISEKSGVPGRLYNSQIAISPEGKIVSIYRKIHVWG 161

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES   + G       ++   K G M CYD  FPE A   +L G+ ++   AAW
Sbjct: 162 LEKLTWRESITCEYGT-----FDMPMCKAGHMICYDTSFPETARVLSLMGSNVIFDSAAW 216

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMP 229
               L+   W     ARA++   +M+ +  CG +      G+SRII P G  +AAA    
Sbjct: 217 RN--LEADIWELNTRARAVENHVFMICSNRCGVEGDSTLNGESRIIGPRGNVLAAAGHEE 274

Query: 230 ALIMAEVTPER-VRQVRAQLPVLNNRRFAPPQLL 262
            +I A++  +  ++     L  + +RR     L+
Sbjct: 275 EIIYADIDIDSCIKDNAMMLSYMKDRRPEAYSLI 308


>UniRef50_A0BLB1 Chromosome undetermined scaffold_114, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0BLB1_PARTE
          Length = 284

 Score =  217 bits (554), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 68/277 (24%), Positives = 116/277 (41%), Gaps = 22/277 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  Q AV    +K  E  A+ +    + +  +  L E        + +   K+A+   
Sbjct: 8   KVALIQNAVFETKQKILEGVAASIRDCVQKECKVIFLGEFFNTIF--ETNQLKKNAEDFS 65

Query: 62  G----EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYD-- 115
                E    +++ S+   +  I  +   +  G+ +N  +A   G +V +Y K HL+D  
Sbjct: 66  DKNNRETYELMKQLSEEFQIMIIGGLPEVA-DGKLFNAALAFNDGKLVGQYRKCHLFDVD 124

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                   ES    +GN+   + + +  + GL  CYD+RFP  +     QG ++L  P+A
Sbjct: 125 IPGGITHFESNTFGSGNDYC-IFDSQYGRYGLGICYDIRFPIYSQVMRDQGCQVLSFPSA 183

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN--------KNIGQSRIIDPFGVTIAA 224
           + +      HW  L  +RALD   Y+ +A             +  G S I DP G  +A 
Sbjct: 184 FNQ-TTGPLHWELLNRSRALDNQVYVASAQAARYYSDDPDYYQTWGHSIITDPMGRVLAT 242

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
               PA+++ E+    V QVR  +P    +R    Q+
Sbjct: 243 CESDPAVLIQEINLSLVDQVRKNIPTSVQKRTDLYQV 279


>UniRef50_Q9ZMC7 Putative n=14 Tax=Helicobacter RepID=Q9ZMC7_HELPJ
          Length = 294

 Score =  217 bits (554), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 70/278 (25%), Positives = 119/278 (42%), Gaps = 33/278 (11%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARD---DHDADLSVKS 56
           +  A  Q         +N ++  +L  +A    A+L  LPE   +     D DAD  +  
Sbjct: 11  LKTAVIQMQSKPYALNENLQLALNLAKEAHNKGANLIVLPELFDSGYCVNDKDADFGLDF 70

Query: 57  ------AQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYA 109
                  + L+ E L  L   +K +    +    +     + ++    +   G IV ++ 
Sbjct: 71  KAIEHGEETLKNETLRALSDFAKSSDTHIVAC-SIEKNNKKLYDSAYIIPPKGKIVGKHR 129

Query: 110 KLHLYDAFAIQESRRVDAGNEIAPLLEVEGM----KVGLMTCYDLRFPELALAQALQGAE 165
           K++L+      E  R   G +   +  ++      KVGL  CY+  F   A    LQGAE
Sbjct: 130 KIYLWG----DEKSRFKRGKKY-EVFTLDFGDFSAKVGLQICYETGFGVGANLLVLQGAE 184

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----------NIGQSRII 215
           +L+ P+A+  G  + ++W  L  ARAL+  C++ A    G +            G SRII
Sbjct: 185 VLIYPSAF--GKARAYNWDLLSKARALENGCFVCACNHSGEETNAKLKQTLEFAGDSRII 242

Query: 216 DPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN 253
            P G  IA A+++  +I+AE+    V   R ++P L +
Sbjct: 243 APNGKIIAQATKLNEVIIAEMDLNEVALQRQKIPYLQD 280


>UniRef50_A5GU42 Nitrilase-related protein n=1 Tax=Synechococcus sp. RCC307
           RepID=A5GU42_SYNR3
          Length = 305

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 73/298 (24%), Positives = 126/298 (42%), Gaps = 42/298 (14%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQA-----AENDASLFALPEALLARDDHDADLSVKSA 57
           VA  QF V+   + N +     + QA       +   L  LPE       + A+   + A
Sbjct: 7   VALVQFQVSPEPQVNRQQVCHWLEQAMTQAGTSSSPKLLMLPEVW--NSPYQAERFAEFA 64

Query: 58  QLL--------EGEF--LGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQA-GNIV 105
           + +        +G    L  +   +  + ++ I   I   S+ GR +N    +   G ++
Sbjct: 65  EPIPELGADLRDGPSDSLKVVADFAVSHRVSVIAGSIPECSSDGRIFNTATVISPAGCLL 124

Query: 106 ARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGM---------KVGLMTCYDLR 151
           A++ K+HL+D          ES  + AG++I  L  V             +GL  CYD+R
Sbjct: 125 AKHRKMHLFDVDIPGGIHFHESDSLTAGDQITVLSGVGDPLASGAATPPNLGLQICYDIR 184

Query: 152 FPELALAQALQ-GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK--- 207
           FPELAL    Q   +++  PA +        HW  ++ ARA+DT  +++A          
Sbjct: 185 FPELALLMQQQLSCDVIACPAGFST-TTGPLHWHLVMRARAVDTQSFVLACCSARPPQDS 243

Query: 208 ----NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
               + G S ++DP+G  +A A     ++ AE+  +++   RA +P    RR    +L
Sbjct: 244 GDYPSYGHSLVVDPWGHIVAEAGIGEEVVHAELDLDQIAAARAAIPTSRQRRGDVYRL 301


>UniRef50_A1RVM3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Thermoproteaceae RepID=A1RVM3_PYRIL
          Length = 269

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 65/260 (25%), Positives = 112/260 (43%), Gaps = 9/260 (3%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +   Q +       N +   SL+     ++  L  LPE  +          + +  + 
Sbjct: 2   FRLGIAQISPG-----NLDKLRSLVG---RSEPDLLLLPEYSMFDPTGLPPEEIWNKAVA 53

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGN-IVARYAKLHLYDAFAI 119
             +F   + R ++      +          + +N  V +  G  +V  Y K HL+DA+  
Sbjct: 54  IEDFTSLIGRLARELGAYVVGGFLERGPRPKVYNTTVLVDPGGRVVGLYRKTHLFDAYGY 113

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +ES  V+ G E++ +  V G +V    C++LRFPE+    AL GA+++ +PAAW  GPLK
Sbjct: 114 KESEFVEPGAELSQVYTVRGARVAFAVCFELRFPEVFRELALAGADLVAVPAAWYAGPLK 173

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
           E     L  ARA++   Y+  +   G +  G+S +++PFGV  A            +   
Sbjct: 174 EEILHILARARAIENGMYIAVSALWGPRFTGRSVVVNPFGVVEAELGAGERYREVLIDLR 233

Query: 240 RVRQVRAQLPVLNNRRFAPP 259
            V + R  +P +  RR    
Sbjct: 234 LVEEARKTVPTIYLRRPHLY 253


>UniRef50_A8MC40 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8MC40_CALMQ
          Length = 279

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 68/261 (26%), Positives = 112/261 (42%), Gaps = 11/261 (4%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLM-AQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           + V   Q+A      E N +   +   A    +   +   PE  +       DL ++ A+
Sbjct: 2   LRVHLIQYASRLGDPEYNIDRLRNYAKANCRGDGNDVLITPELYIPGY-MSRDLLLQIAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTP-GRAWNMLVALQAGNIVARYAKLHLYDAF 117
            L+G+ +G L   ++    T I  I       G  +N  VA+    ++A Y K HL    
Sbjct: 61  PLDGKSIGELTEIAREGKCTIITGIAERDKDTGVVYNSAVAIGENGLMALYRKRHLPSYG 120

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              ESR    G   AP+  + G K GL  CYD  +PE++ +  L+GA + V  +A     
Sbjct: 121 VFDESRYFGVGRGDAPVFSMNGTKAGLAICYDAFYPEVSRSLMLKGARVQVYISA--APD 178

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAAS-EMPALI 232
           +   H+ T + ARA++   +++     G        G S I+DP G  +A A       +
Sbjct: 179 MSRPHFETFIRARAMENVSFVIYVNTIGQYDGLGFFGGSFIVDPLGEVVAKAKYYEEDTV 238

Query: 233 MAEVTPERVRQVRAQLPVLNN 253
           +AE+ P  V   R+  P+L +
Sbjct: 239 VAEIDPGLVDNYRSIRPILKD 259


>UniRef50_A6TL48 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Bacteria RepID=A6TL48_ALKMQ
          Length = 296

 Score =  217 bits (553), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 64/270 (23%), Positives = 115/270 (42%), Gaps = 21/270 (7%)

Query: 2   LVAAGQFAVTSV-WEKNAEICASLMAQAAEN-DASLFALPEALLARDD--HDADLSVKSA 57
           + A  Q A+     ++N E  A  + +AA+  +A L   PE++          D   +  
Sbjct: 5   IAACVQIAIKPNEIQRNIEKAAYWLERAAKEYEAELVVFPESITTGFSPNMTVDAFYEIL 64

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGR-AWNMLVALQA-GNIVARYAKLHLYD 115
           + + G     +++ +K      +  ++      R  +N  + +   G I+ +Y K H + 
Sbjct: 65  EPIPGRHTRDIQKLAKELGTHVVFPLYERGKNKREVFNSSLMIDDRGEIIGKYRKTHPFP 124

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +       GNE   +++ +  K+G++ CYD  FPEL+   AL+GAEI+  P+A +R
Sbjct: 125 TERKEGGGWTTPGNE-TVVVDTKLGKIGMIICYDGDFPELSRVLALKGAEIITRPSALLR 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPA 230
                  W     ARA D   Y++     G         G S I+ P   T+A A     
Sbjct: 184 SF---EIWEMTNKARAYDNHVYVLGVNAIGPDAAENYYFGHSMIVSPIAQTLAQARGTEE 240

Query: 231 LIMAEVTPERVRQV----RA--QLPVLNNR 254
           +I A++ P+ ++ V    R+      L +R
Sbjct: 241 IIAAKLDPDPIKYVSYGTRSPMIFDHLEDR 270


>UniRef50_Q1MYM0 Predicted amidohydrolase n=1 Tax=Bermanella marisrubri
           RepID=Q1MYM0_9GAMM
          Length = 274

 Score =  217 bits (553), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 65/271 (23%), Positives = 116/271 (42%), Gaps = 17/271 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + V   Q       + N     + + +  E  A+   LPE  +     +     ++    
Sbjct: 6   ITVGLVQMTSGKAVQPNLRAAEAAIKRCVEQGATTVLLPEMFVCLGVKNQVEIAQTQCQK 65

Query: 61  EGEFLGRLRRESKR---NMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDA- 116
            G    +L   +K    N++   + +            LV    G+ V +Y K+HL+D  
Sbjct: 66  GGPVRSQLSALAKDFKVNIIAGSMPLMSSVEDKVLAACLVFAADGSEVCQYDKVHLFDVD 125

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES    AG +   +  ++G   GL  CYDLRFPEL      Q  +++ +P+
Sbjct: 126 VSDNKGRYRESDTFIAGTQSKTV-SLDGTLYGLSVCYDLRFPELYQQYQKQSCQVVTVPS 184

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAAS 226
           A+      + HW TLL ARA++T  +++AA + G         GQS +I+P G  +    
Sbjct: 185 AFTY-TTGQKHWLTLLKARAIETQSFVMAANQVGTHEDGRITWGQSIVINPDGEIVGELD 243

Query: 227 -EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            E    ++ E+  E  +++R  +P+L ++R 
Sbjct: 244 SEKAGELVVELDLELCQKIRQSMPLLKHKRL 274


>UniRef50_B1MI91 Hypothetical carbon-nitrogen hydrolase family protein n=1
           Tax=Mycobacterium abscessus ATCC 19977
           RepID=B1MI91_MYCA9
          Length = 266

 Score =  216 bits (552), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 11/260 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q +  +   + N    A     AA  DA L   PE  L   +         AQ 
Sbjct: 5   LRLAVVQCSSQAADVQANLARLAETAHAAAAGDAQLVVFPEMYLTGYNIGEWDIRDLAQS 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            +G  +  +R+ +    M   +     ++ G+ +N  +     G +V  Y K HL+    
Sbjct: 65  PDGPAMQFIRQTACDADMHICVGYPERASDGQIYNSALICDPRGRVVLNYRKSHLF---G 121

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E           PL  V G+ VGL+ CYD+ FPE   A A+  A+++V+P A +    
Sbjct: 122 DTERNVFTRPGPQLPLAVVHGVSVGLLICYDVEFPENVRALAMARADVVVVPTANMEPFH 181

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
                 T++ ARA +   Y+  A  CGN       G S I+ P G  +A A E   L++A
Sbjct: 182 --AVCETVVPARAYENQLYVAYANYCGNHDGLAYCGGSSIVGPDGTALARAGEGVGLLVA 239

Query: 235 EVTPERVRQVRAQLPVLNNR 254
           +V    + + R++   L +R
Sbjct: 240 DVDRAVIDRTRSRHCFLEDR 259


>UniRef50_B0MXF9 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MXF9_9BACT
          Length = 253

 Score =  216 bits (552), Expect = 5e-55,   Method: Composition-based stats.
 Identities = 65/258 (25%), Positives = 107/258 (41%), Gaps = 19/258 (7%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + VA  QF +       N      ++A+A   DA L  LPE        D     + AQ 
Sbjct: 3   LKVALCQFDMVWEDTAANLRTAGRMVAEA---DADLVILPEMFATGFVTDPG---RVAQP 56

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           + GE +  + R  +        ++ V    GR +N L+ ++      +  K HL+     
Sbjct: 57  MSGEIVQEMTRWVRTTGKAVAGSLIVEE-EGRYYNRLLFIKPSGERVQSDKRHLFSIGG- 114

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E      G E   ++E  G++  L  CYDLRFP  +        + ++  A+W  G  +
Sbjct: 115 -EGANFCPGRERG-VVEYGGIRFLLQVCYDLRFPVWSRC--RNDYDAIIYVASWPAG--R 168

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMAE 235
              W TLL ARA++   Y++     G+       G S +I   G T+A A E   L+ A 
Sbjct: 169 RDVWRTLLRARAIENQAYVLGVNRTGDDPRLHYSGDSAVIGCKGETLAEAGEGETLLTAR 228

Query: 236 VTPERVRQVRAQLPVLNN 253
           +  + +R+ R + P   +
Sbjct: 229 LDMDELRRFREKFPAWRD 246


>UniRef50_Q04W18 Amidohydrolase n=4 Tax=Leptospira RepID=Q04W18_LEPBJ
          Length = 280

 Score =  216 bits (550), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 60/268 (22%), Positives = 107/268 (39%), Gaps = 22/268 (8%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQA----AENDASLFALPEALLARDDHDADLSVK 55
           + +A  Q  ++    E N E    L+  A     + +  L  LPE         ++   +
Sbjct: 6   LNIALVQCDLSWENRETNYEHVRELIHSALEKQTDKNPDLILLPETFATGFTMRSE---R 62

Query: 56  SAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLY 114
           +A+  EG     L+  +K    T        +  G+ +N   V    G I+ RY+K+H +
Sbjct: 63  TAEPDEGPTETFLKEIAKDAKTTICGGWIQKNPKGKPFNTVSVVSPKGEIILRYSKIHPF 122

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                 E R   +G+EI    ++ G ++    CYD+RFPE+    A +  +I  + A W 
Sbjct: 123 TFGG--EDRHYSSGSEIVS-YDLNGFRITPFICYDIRFPEIFRRLAGE-TDIFTVHANWP 178

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECG-------NKNIGQSRIIDPFGVTIAAASE 227
               + HHW  +L  RA++   Y+      G         + G S  + P G  +     
Sbjct: 179 --TPRIHHWELILKTRAIENQAYVFGINRIGIAGHNKSIHHNGHSLAVAPNGDFMDVGEG 236

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
           +  ++        +   R   PVL++R+
Sbjct: 237 IETVLFYNARKRLILDYRENFPVLSDRK 264


>UniRef50_Q6AMZ4 Putative uncharacterized protein n=1 Tax=Desulfotalea psychrophila
           RepID=Q6AMZ4_DESPS
          Length = 258

 Score =  216 bits (550), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 70/261 (26%), Positives = 116/261 (44%), Gaps = 13/261 (4%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M ++A Q AV       +     + +    E+   L  LPE        +       A+ 
Sbjct: 1   MKISAIQLAVVEDDKAASIARARTEIELCRES--DLIILPEIWNTGF-MNFAAYRSLAEE 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFA 118
            +G  L  +R  + +          V     + +N    +   G+I+  Y K+HL+  FA
Sbjct: 58  RKGPTLSMVREMAVKTSSFIHSGSFVEKIEDKYYNSSYLISPDGDILGNYRKIHLF-GFA 116

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E+  + AG EI+ ++  +   +G+ TC+DLRFPEL      QG EI ++ AAW    L
Sbjct: 117 SLETEILSAGQEIS-VINTKLGIIGMATCFDLRFPELFRKMVDQGTEIFLICAAWPLARL 175

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMA 234
            +  W+ L   RAL+    +++A   G     +  G S I+ P G  +A A +M   I A
Sbjct: 176 AD--WALLNRVRALENQALLISANARGMSKGVQLAGNSMIVGPNGQILAQADDMDNSISA 233

Query: 235 EVTPERVRQVRAQLPVLNNRR 255
           E+    V++ R   P L++R+
Sbjct: 234 EINLNAVKEARCSFPALSSRK 254


>UniRef50_B1K4S5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=12 Tax=Proteobacteria RepID=B1K4S5_BURCC
          Length = 299

 Score =  216 bits (550), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 108/271 (39%), Gaps = 21/271 (7%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARD-DHDADLSVKSAQ 58
             +A  Q        + N       +  AA N A+L  LPE   +     D D ++  A+
Sbjct: 17  FTIACVQMEPRIGAAQHNLATALDRIETAARNGAALIVLPELASSGYVFEDRDEALALAE 76

Query: 59  L-LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
           L  +G         ++R  +  +  I       R +N  +    G  +  Y KLHL+D  
Sbjct: 77  LVPDGPTARAFEAIARRLNVHIVSGIAERDGA-RLYNSALFAGPGGHLGVYRKLHLWD-- 133

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E R  + G+   P+ +    ++ +  CYD+ FPE      +QGA+++ +P  WV  P
Sbjct: 134 --NEKRFFEPGDRGVPVFDTPLGRIAMAICYDVWFPETFRLAVMQGADLVCVPTNWVPMP 191

Query: 178 ----LKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIA--AASE 227
                +    +TL  A A      +  A   G +     IGQS I+   G  +A  A+ +
Sbjct: 192 SQPDDRPGMATTLTMAAAHSNGIAIACADRVGIERDQPFIGQSLIVGGDGWPVAGPASID 251

Query: 228 MPALIMAEVTPERVRQVR---AQLPVLNNRR 255
              ++   +   R R  R   A   VL +RR
Sbjct: 252 REEIVYGTIDVARTRAGRALNAHNHVLRDRR 282


>UniRef50_Q6BU62 DEHA2C13310p n=6 Tax=Saccharomycetales RepID=Q6BU62_DEBHA
          Length = 312

 Score =  216 bits (550), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 85/303 (28%), Positives = 135/303 (44%), Gaps = 49/303 (16%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA GQ   +S    NA I   L+ +A    A +  LPEA       DA  S++ AQ  
Sbjct: 5   VRVACGQLCSSSNLSSNANIVKKLIRKAVTAKAKVLFLPEATDYI-AKDAIQSMQLAQSS 63

Query: 61  EGEFLGRLRRESKR------NMMTTILTIHVPSTP---------GRAWNMLVALQA-GNI 104
             +F+  ++RE K       + +   + +H PS+           +  N  + +   G I
Sbjct: 64  HEKFISDIQRELKEVYADNGDGLFVAVGVHEPSSSTGVNAKEILNKVSNNQLWIGNRGEI 123

Query: 105 VARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVE-----GMKVGLMTCYDLRFPE 154
           + RY KLHL+D        ++ES  V+ G+ +     +         +G  TCYD+RFPE
Sbjct: 124 LHRYQKLHLFDINIENGPILKESNSVEPGSSVLKPFPINTSSLSEFLIGFATCYDIRFPE 183

Query: 155 LALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN------ 208
           L L     GA I+  P+A+      + HW  L  ARA+DT CY+V A +CG  +      
Sbjct: 184 LGLRLRSLGANIITYPSAFTT-KTGQAHWELLARARAVDTQCYVVMAAQCGEHDTGGDKK 242

Query: 209 ---IGQSRIIDPFGVTIAAA------------SEMPALIMAEVTPERVRQVRAQLPVLNN 253
               G S IIDP+G  I+               +   + +A++  + V + R  +P++ +
Sbjct: 243 RISYGNSIIIDPWGNKISECHKYNEDLVVDSEGDYYEMCVADLDLDMVEKTRRDMPLMTH 302

Query: 254 RRF 256
           RR 
Sbjct: 303 RRP 305


>UniRef50_A7H2U5 Carbon-nitrogen hydrolase n=5 Tax=Campylobacterales
           RepID=A7H2U5_CAMJD
          Length = 279

 Score =  216 bits (550), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 69/274 (25%), Positives = 116/274 (42%), Gaps = 22/274 (8%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           +  A  QFA  S   E+N          A E  A L  LPE   +    + D     A  
Sbjct: 5   LKAALIQFAPLSYEREQNLNKSLIFTQTALEQGAKLVVLPELFDSGYCVE-DKDFSYALS 63

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           LE E    L+  +K+     I    +       ++    +    +V +Y K++L+     
Sbjct: 64  LEKELPSSLKELAKKYEAYIIAC-SIEKEDDTLYDTAFIVGKEGLVGKYRKIYLFR---- 118

Query: 120 QESRRVDAGNEIAP---LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
            E +R   G +      + +   +K+GL  CY++ F E A   ALQGAE++  P+A+  G
Sbjct: 119 DEKKRFARGQDYPVFELVFKDFSLKLGLQICYEIGFGEGARFLALQGAELICYPSAF--G 176

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGN----------KNIGQSRIIDPFGVTIAAAS 226
             + + W     ARAL++  +++AA  CG+          +  G+S+II+P G  ++  S
Sbjct: 177 KARAYVWDLASRARALESGAFVLAANRCGSEISKLSGENLEFAGRSKIINPKGEILSELS 236

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           E   +  A +   +V+  R  L  L +      Q
Sbjct: 237 EKEGISYAVLDITQVKAQREYLTYLKDLDLDLSQ 270


>UniRef50_Q5KLT5 Nitrilase-like protein, putative n=2 Tax=Filobasidiella neoformans
           RepID=Q5KLT5_CRYNE
          Length = 356

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 78/302 (25%), Positives = 126/302 (41%), Gaps = 49/302 (16%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  Q   TS    N +I   ++  A    A    LPEA    +    +    S  L +
Sbjct: 45  TVAVCQLRSTSDPVHNLKISEKVIRNAVAAGAKACFLPEASDFINPSKTESRKFSHPLPK 104

Query: 62  GEFLGRLRRESKRNMMTTILTIH---VPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
            E+   L+R +K   +   + +H      +  R +N  V +   G I+A Y K+HL+D  
Sbjct: 105 HEYTIGLQRLAKELGIVISVGVHEGPEDESEERVYNTHVLIGKDGGILASYRKIHLFDVE 164

Query: 118 ---------------AIQESRRVDAGNEIAPLLEVEG-MKVGLMTCYDLRFPELALAQAL 161
                             ES R+ AG  + P +EVEG   +GL  CYD+RFPEL++    
Sbjct: 165 LSKPPAPDGTPRPPQRTGESERILAGQAVTPPVEVEGIGNIGLEICYDIRFPELSIILTR 224

Query: 162 QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIID 216
            GAE+L+ P+A+     ++ HW TL  A A+    Y++A+ + G  N      G++   D
Sbjct: 225 LGAEVLLFPSAFTVKTGRD-HWGTLCRATAIQYQSYLIASAQYGAHNSKRTSWGETLAFD 283

Query: 217 PFGVTIAAAS---------EMP--------------ALIMAEVTPERVRQVRAQLPVLNN 253
           P+G  +             E                   + E+   +V++ R Q+P+   
Sbjct: 284 PWGRQLGRLRSVDDTPPPKEGEEGDKGVEKLYEDSGEFFLCEIDGTKVKETRGQIPLAIQ 343

Query: 254 RR 255
           +R
Sbjct: 344 KR 345


>UniRef50_A0B689 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Methanosaeta thermophila PT RepID=A0B689_METTP
          Length = 245

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 70/260 (26%), Positives = 108/260 (41%), Gaps = 16/260 (6%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M  A  Q +V       N      L +  A+  A +  LPE  L    +D        + 
Sbjct: 1   MRAACVQLSVRECDVGDNKRRALQLSSDVADIGADIIVLPELFLTGFCYDLK-----PES 55

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           +    L   R  S  +    + +I   S  G   NM   + AG     Y K H +     
Sbjct: 56  IPYPSLMSFRALSLDSGAILVGSIMASSDRGPI-NMGFCM-AGAETGFYCKTHPFG---- 109

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E +    G  IAP+ +V G+ +GL  CYD+RFPE+A      GA++LV  A +     +
Sbjct: 110 DEKKHFIPGEIIAPV-KVGGLSIGLEICYDIRFPEVARKLCASGADLLVTIAQFPAE--R 166

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
            HHW  L+ ARA++   + +A    G+   G S I+ P G  +A A     +I A++  +
Sbjct: 167 IHHWRALVTARAIENQIHHIACNASGSAG-GSSMIVGPAGEVLAEAGVEECVITADLDLD 225

Query: 240 RVRQVRAQLPVLNNRRFAPP 259
              +VR  +    +RR    
Sbjct: 226 ERDRVRRAITCWEDRRPELY 245


>UniRef50_A3CTE8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Methanoculleus marisnigri JR1 RepID=A3CTE8_METMJ
          Length = 265

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 75/231 (32%), Positives = 102/231 (44%), Gaps = 11/231 (4%)

Query: 34  SLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAW 93
           SL   PE  +        +   S + L+G       R ++ N +    +I       R  
Sbjct: 36  SLICFPEQFVTG--WSPKVPPGSGEPLDGPLTAAFARIAEENGIAVAGSIVEAGLENRPK 93

Query: 94  NMLVALQ-AGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRF 152
           N  V L   G ++A YAK+HL+      E R   AG+ IA    V+G+K G+  CYDLRF
Sbjct: 94  NTTVVLDEDGELLAAYAKIHLFSPEG--EDRYYTAGDRIAT-FTVDGVKFGIAVCYDLRF 150

Query: 153 PELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN---I 209
           PEL    A+ G E +++PAAW    L   HW TLL ARAL+   Y+      G       
Sbjct: 151 PELFRIYAIAGVECMLVPAAWPCSRLS--HWETLLPARALENRYYVTGVNTAGRPGAPCC 208

Query: 210 GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           G S   DP G  I         I  EV P  V + ++ LP L++RR     
Sbjct: 209 GGSLAADPDGTVIGRCGAGEEAISIEVDPVAVHEAQSSLPSLSDRRSDLYH 259


>UniRef50_UPI0001AEF4A9 hypothetical protein SghaA1_01010 n=1 Tax=Streptomyces ghanaensis
           ATCC 14672 RepID=UPI0001AEF4A9
          Length = 288

 Score =  214 bits (545), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 66/272 (24%), Positives = 109/272 (40%), Gaps = 17/272 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARD-DHDADLSVKSAQ 58
           + VA+ Q A      E+N       + +AA   AS+  LPE   +     D +  +  A+
Sbjct: 13  VTVASCQIAPRVGRVEENRHRIREAIEEAARRGASIVVLPELANSGYVFQDLEELLSVAE 72

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
            L+G  + +    + R  +  +       + GRA+N  V +    I A Y K HL+D   
Sbjct: 73  PLDGATVRQWEELAARLKLVIVGGFAELGSDGRAYNSAVLIDETGIRASYRKAHLWDG-- 130

Query: 119 IQESRR-VDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
             E       G+   P+++    ++G++ CYDL FPE     AL+GAE+L  P  W   P
Sbjct: 131 --EKTWGFTPGDTRPPVVDTPHGRIGMLICYDLEFPEWVRLAALEGAELLCGPVNWPLYP 188

Query: 178 LKEHHWS---TLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAAS-EMP 229
             E         + A A     ++  A   G +     +G S I+D  G  +        
Sbjct: 189 RPEGERPGEVIRVQANAAVNRMFVAVADRTGTERGQDWLGGSVIVDADGYPVTELRLGEE 248

Query: 230 ALIMAEVTPERVRQ--VRAQLPVLNNRRFAPP 259
           A++ A +     R   +  +  V  +RR    
Sbjct: 249 AVVTATLDLTEARDKSISDRNDVHADRRPELY 280


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q28IE5 Omega-amidase NIT2 n=42 Tax=cellular organisms R...   343   4e-93
UniRef50_Q9NQR4 Omega-amidase NIT2 n=88 Tax=Eukaryota RepID=NIT2...   337   2e-91
UniRef50_C0Z4R2 Putative uncharacterized protein n=1 Tax=Breviba...   333   4e-90
UniRef50_C8VW38 Nitrilase/cyanide hydratase and apolipoprotein N...   326   6e-88
UniRef50_B9L3Z7 Hydrolase, carbon-nitrogen family protein n=8 Ta...   323   3e-87
UniRef50_B9ZGS1 Nitrilase/cyanide hydratase and apolipoprotein N...   323   3e-87
UniRef50_C6CYG4 Nitrilase/cyanide hydratase and apolipoprotein N...   321   1e-86
UniRef50_A1HPP3 Nitrilase/cyanide hydratase and apolipoprotein N...   320   2e-86
UniRef50_A5N8H1 Predicted hydrolase n=3 Tax=Clostridium RepID=A5...   318   1e-85
UniRef50_B9HD27 Predicted protein n=8 Tax=Magnoliophyta RepID=B9...   318   2e-85
UniRef50_Q8RUF8 AT5g12040/F14F18_210 n=16 Tax=Eukaryota RepID=Q8...   317   2e-85
UniRef50_Q7TQ94 Nitrilase homolog 1 n=6 Tax=Coelomata RepID=NIT1...   315   7e-85
UniRef50_UPI0001924654 PREDICTED: similar to Nit protein 1 n=1 T...   313   4e-84
UniRef50_Q86X76 Nitrilase homolog 1 n=34 Tax=Eumetazoa RepID=NIT...   312   7e-84
UniRef50_C1TRG7 Predicted amidohydrolase n=1 Tax=Dethiosulfovibr...   311   2e-83
UniRef50_UPI000197C0D6 hypothetical protein PretD1_21713 n=1 Tax...   309   6e-83
UniRef50_UPI000186DBB5 conserved hypothetical protein n=1 Tax=Pe...   309   8e-83
UniRef50_A9A651 Nitrilase/cyanide hydratase and apolipoprotein N...   309   8e-83
UniRef50_Q54JM9 Nitrilase homolog 2 n=1 Tax=Dictyostelium discoi...   306   4e-82
UniRef50_Q9HIW8 Nitrilase related protein n=2 Tax=Thermoplasma R...   305   1e-81
UniRef50_Q2QQ94 Os12g0502500 protein n=5 Tax=Spermatophyta RepID...   303   3e-81
UniRef50_Q2NHR0 Predicted amidohydrolase n=1 Tax=Methanosphaera ...   303   3e-81
UniRef50_D2RIK2 Nitrilase/cyanide hydratase and apolipoprotein N...   302   9e-81
UniRef50_A2FF61 Hydrolase NIT3, putative n=4 Tax=cellular organi...   301   1e-80
UniRef50_D2UDH5 Putative carbon-nitrogen hydrolase family protei...   301   1e-80
UniRef50_B2SLI2 Beta-alanine synthetase n=122 Tax=Bacteria RepID...   300   2e-80
UniRef50_A1HQ26 Nitrilase/cyanide hydratase and apolipoprotein N...   300   3e-80
UniRef50_UPI000051A529 PREDICTED: similar to Nitrilase and fragi...   299   5e-80
UniRef50_Q0AX54 N-carbamoyl-D-amino acid amidohydrolase n=3 Tax=...   299   5e-80
UniRef50_C8WPR2 Nitrilase/cyanide hydratase and apolipoprotein N...   299   6e-80
UniRef50_O76463 Nitrilase homolog n=6 Tax=Bilateria RepID=NFT1_C...   299   8e-80
UniRef50_B1I274 Nitrilase/cyanide hydratase and apolipoprotein N...   299   9e-80
UniRef50_B6K212 UPF0012 hydrolase n=1 Tax=Schizosaccharomyces ja...   298   1e-79
UniRef50_B3E274 Nitrilase/cyanide hydratase and apolipoprotein N...   298   1e-79
UniRef50_A8MG18 Nitrilase/cyanide hydratase and apolipoprotein N...   297   2e-79
UniRef50_D2R0U8 Nitrilase/cyanide hydratase and apolipoprotein N...   297   3e-79
UniRef50_Q7MHE3 Predicted amidohydrolase n=69 Tax=Proteobacteria...   296   5e-79
UniRef50_D1Y612 Hydrolase n=2 Tax=Bacteria RepID=D1Y612_9BACT         296   5e-79
UniRef50_A6DKQ0 Carbon-nitrogen hydrolase family protein n=1 Tax...   296   6e-79
UniRef50_D1Y5M0 Hydrolase C26A3.11 n=1 Tax=Pyramidobacter piscol...   296   6e-79
UniRef50_O76464 Nitrilase homolog n=6 Tax=Sophophora RepID=NFT1_...   294   2e-78
UniRef50_D1VY57 Hydrolase, carbon-nitrogen family n=1 Tax=Prevot...   294   2e-78
UniRef50_C4XZI3 Putative uncharacterized protein n=1 Tax=Clavisp...   294   2e-78
UniRef50_A0L7H1 Nitrilase/cyanide hydratase and apolipoprotein N...   293   4e-78
UniRef50_B0SIF2 Amidohydrolase n=3 Tax=Bacteria RepID=B0SIF2_LEPBA    293   5e-78
UniRef50_Q2BKP4 Putative carbon-nitrogen hydrolase n=1 Tax=Neptu...   291   1e-77
UniRef50_B0MEV6 Putative uncharacterized protein n=2 Tax=Clostri...   291   1e-77
UniRef50_O31664 UPF0012 hydrolase mtnU n=96 Tax=Bacilli RepID=MT...   291   2e-77
UniRef50_A7GE66 Hydrolase, carbon-nitrogen family n=24 Tax=cellu...   290   3e-77
UniRef50_B0TEY4 Hydrolase, carbon-nitrogen family n=1 Tax=Heliob...   290   4e-77
UniRef50_Q0HEI5 Nitrilase/cyanide hydratase and apolipoprotein N...   290   4e-77
UniRef50_Q702A9 Putative predicted amidohydrolase n=6 Tax=Archae...   289   6e-77
UniRef50_Q9KE11 BH1047 protein n=2 Tax=Bacillaceae RepID=Q9KE11_...   289   8e-77
UniRef50_A5VIE2 Nitrilase/cyanide hydratase and apolipoprotein N...   288   1e-76
UniRef50_Q972L1 281aa long hypothetical beta-ureidopropionase n=...   288   1e-76
UniRef50_Q557J5 Nitrilase homolog 1 n=1 Tax=Dictyostelium discoi...   288   1e-76
UniRef50_P58054 UPF0012 hydrolase ybeM n=121 Tax=Proteobacteria ...   288   1e-76
UniRef50_B2SXB2 Nitrilase/cyanide hydratase and apolipoprotein N...   287   2e-76
UniRef50_Q12ZA5 Carbon-nitrogen hydrolase family protein n=1 Tax...   287   2e-76
UniRef50_A7A823 Putative uncharacterized protein n=2 Tax=Bifidob...   287   2e-76
UniRef50_Q7QKM8 AGAP012662-PA (Fragment) n=14 Tax=Neoptera RepID...   286   4e-76
UniRef50_A1SD43 Nitrilase/cyanide hydratase and apolipoprotein N...   286   5e-76
UniRef50_A9WV78 Hydrolase, carbon-nitrogen family n=3 Tax=Microc...   286   6e-76
UniRef50_A6F4Z1 Predicted amidohydrolase n=2 Tax=Marinobacter Re...   285   8e-76
UniRef50_D2A1E5 Putative uncharacterized protein GLEAN_07103 n=3...   285   9e-76
UniRef50_B0KGW5 N-carbamoylputrescine amidase n=60 Tax=Bacteria ...   285   9e-76
UniRef50_Q1PXD4 Similar to N-carbamoyl-D-amino acid hydrolase n=...   285   1e-75
UniRef50_B2J6W4 Nitrilase/cyanide hydratase and apolipoprotein N...   285   1e-75
UniRef50_B8C1M9 Nitrilase n=1 Tax=Thalassiosira pseudonana RepID...   285   1e-75
UniRef50_A2BNC1 Predicted amidohydrolase n=1 Tax=Hyperthermus bu...   285   1e-75
UniRef50_D1Y828 Hydrolase n=1 Tax=Pyramidobacter piscolens W5455...   285   1e-75
UniRef50_A8I529 Carbon-nitrogen hydrolase family protein n=8 Tax...   284   1e-75
UniRef50_C1AA71 N-carbamoylputrescine amidohydrolase n=12 Tax=Ba...   284   2e-75
UniRef50_Q5DC61 SJCHGC06938 protein n=1 Tax=Schistosoma japonicu...   284   2e-75
UniRef50_C7R9G8 Nitrilase/cyanide hydratase and apolipoprotein N...   284   2e-75
UniRef50_Q0F1V1 Hydrolase, carbon-nitrogen family protein n=1 Ta...   284   2e-75
UniRef50_UPI0000E7FA0A PREDICTED: hypothetical protein isoform 1...   284   2e-75
UniRef50_A5GT50 Possible nitrilase n=5 Tax=Bacteria RepID=A5GT50...   284   2e-75
UniRef50_Q1QX75 Nitrilase/cyanide hydratase and apolipoprotein N...   284   3e-75
UniRef50_Q724C2 Hydrolase, carbon-nitrogen family n=20 Tax=Bacil...   283   3e-75
UniRef50_C6JLR5 Nitrilase/cyanide hydratase and apolipoprotein N...   283   4e-75
UniRef50_C2BXL2 Cyanide hydratase n=1 Tax=Listeria grayi DSM 206...   283   4e-75
UniRef50_P55175 UPF0012 hydrolase sll0601 n=46 Tax=Cyanobacteria...   283   4e-75
UniRef50_A3ZLM3 Putative nitrilase n=1 Tax=Blastopirellula marin...   283   4e-75
UniRef50_Q5WM18 Methylthioribose recycling protein n=3 Tax=Bacil...   283   5e-75
UniRef50_B6YW48 Carbon-nitrogen hydrolase n=4 Tax=cellular organ...   283   5e-75
UniRef50_A4J4S3 Nitrilase/cyanide hydratase and apolipoprotein N...   282   5e-75
UniRef50_B5JWE9 Nitrilase/cyanide hydratase and apolipoprotein N...   282   9e-75
UniRef50_C7ICC9 Nitrilase/cyanide hydratase and apolipoprotein N...   282   1e-74
UniRef50_Q15NS3 Nitrilase/cyanide hydratase and apolipoprotein N...   282   1e-74
UniRef50_UPI0001B416B7 carbon-nitrogen hydrolase n=1 Tax=Ferropl...   281   1e-74
UniRef50_Q8VYF5 N-carbamoylputrescine amidase n=162 Tax=cellular...   281   1e-74
UniRef50_A7I5W9 Porphyromonas-type peptidyl-arginine deiminase n...   281   1e-74
UniRef50_Q1LEX6 Nitrilase/cyanide hydratase and apolipoprotein N...   281   2e-74
UniRef50_C4QCM8 Nitrilase-related n=1 Tax=Schistosoma mansoni Re...   281   2e-74
UniRef50_Q94JV5 AT4g08790/T32A17_100 n=10 Tax=Viridiplantae RepI...   281   2e-74
UniRef50_A5V962 Nitrilase/cyanide hydratase and apolipoprotein N...   280   3e-74
UniRef50_A4ALG5 Putative hydrolase n=1 Tax=marine actinobacteriu...   280   4e-74
UniRef50_C0GEE7 Nitrilase/cyanide hydratase and apolipoprotein N...   280   4e-74
UniRef50_Q23ND3 Hydrolase, carbon-nitrogen family protein n=1 Ta...   279   5e-74
UniRef50_C7CES6 Putative N-carbamyl-D-amino acid amidohydrolase ...   279   5e-74
UniRef50_C1SI84 Predicted amidohydrolase n=1 Tax=Denitrovibrio a...   279   6e-74
UniRef50_A1WYY7 Nitrilase/cyanide hydratase and apolipoprotein N...   278   1e-73
UniRef50_Q9LE50 Nitrilase 1 like protein n=2 Tax=Viridiplantae R...   278   2e-73
UniRef50_Q2JDM2 Nitrilase/cyanide hydratase and apolipoprotein N...   278   2e-73
UniRef50_B6HUF1 Pc22g05380 protein n=28 Tax=Leotiomyceta RepID=B...   277   2e-73
UniRef50_Q0S3S2 Possible amidohydrolase, carbon-nitrogen hydrola...   277   2e-73
UniRef50_Q3SLE9 Carbon-nitrogen hydrolase n=101 Tax=Proteobacter...   277   2e-73
UniRef50_C6N396 Nitrilase n=2 Tax=Legionella RepID=C6N396_9GAMM       277   2e-73
UniRef50_A8IKB0 Nitrilase/cyanide hydratase and apolipoprotein N...   277   3e-73
UniRef50_Q1AWK1 Nitrilase/cyanide hydratase and apolipoprotein N...   276   4e-73
UniRef50_A7IJX5 Nitrilase/cyanide hydratase and apolipoprotein N...   276   4e-73
UniRef50_Q0S9Y1 Possible nitrilase n=3 Tax=Actinomycetales RepID...   276   5e-73
UniRef50_A9B254 Nitrilase/cyanide hydratase and apolipoprotein N...   276   7e-73
UniRef50_C9KQR5 Hydrolase, carbon-nitrogen family n=1 Tax=Mitsuo...   276   7e-73
UniRef50_C7TF35 Hydrolase, carbon-nitrogen family n=17 Tax=Lacto...   275   9e-73
UniRef50_Q02J62 Putative N-carbamoylputrescine amidohydrolase n=...   275   9e-73
UniRef50_A0BR54 Chromosome undetermined scaffold_122, whole geno...   274   1e-72
UniRef50_Q2N7J4 Hydrolase n=5 Tax=Sphingomonadales RepID=Q2N7J4_...   274   2e-72
UniRef50_A4S5E0 Predicted protein n=2 Tax=Ostreococcus RepID=A4S...   274   2e-72
UniRef50_Q65KK0 Methylthioribose recycling protein n=1 Tax=Bacil...   274   2e-72
UniRef50_C1N8C1 Predicted protein n=1 Tax=Micromonas pusilla CCM...   274   3e-72
UniRef50_A0LH50 Nitrilase/cyanide hydratase and apolipoprotein N...   274   3e-72
UniRef50_D2RS34 Nitrilase/cyanide hydratase and apolipoprotein N...   274   3e-72
UniRef50_C5L8W7 Putative uncharacterized protein n=2 Tax=Perkins...   273   3e-72
UniRef50_D1BL17 Nitrilase/cyanide hydratase and apolipoprotein N...   272   7e-72
UniRef50_D1NXA0 Hydrolase, carbon-nitrogen family n=8 Tax=Entero...   272   1e-71
UniRef50_D1BX77 Nitrilase/cyanide hydratase and apolipoprotein N...   271   1e-71
UniRef50_A1RZK0 Nitrilase/cyanide hydratase and apolipoprotein N...   271   1e-71
UniRef50_Q1YU23 Hydrolase, carbon-nitrogen family protein n=1 Ta...   271   1e-71
UniRef50_UPI0001BC35FB amidohydrolase n=1 Tax=Butyrivibrio cross...   271   2e-71
UniRef50_C0ZEK3 Beta-alanine synthase n=59 Tax=Bacteria RepID=C0...   271   2e-71
UniRef50_C0D6C3 Putative uncharacterized protein n=1 Tax=Clostri...   270   3e-71
UniRef50_Q1QTM0 Nitrilase/cyanide hydratase and apolipoprotein N...   270   3e-71
UniRef50_C4DVK2 Predicted amidohydrolase n=1 Tax=Stackebrandtia ...   270   3e-71
UniRef50_D0L1I4 Nitrilase/cyanide hydratase and apolipoprotein N...   270   3e-71
UniRef50_C7N2Y0 Predicted amidohydrolase n=1 Tax=Slackia heliotr...   270   3e-71
UniRef50_C7NXL9 Nitrilase/cyanide hydratase and apolipoprotein N...   270   4e-71
UniRef50_A4SSL0 Beta-ureidopropionase n=2 Tax=Gammaproteobacteri...   270   4e-71
UniRef50_A2Q9D7 Catalytic activity: nitrilases catalyze a nitril...   270   4e-71
UniRef50_D1A7Y1 Nitrilase/cyanide hydratase and apolipoprotein N...   269   4e-71
UniRef50_A5G317 Nitrilase/cyanide hydratase and apolipoprotein N...   269   5e-71
UniRef50_Q4Q8W4 Nitrilase, putative n=7 Tax=Trypanosomatidae Rep...   269   5e-71
UniRef50_Q46AW4 Putative amidohydrolase n=1 Tax=Methanosarcina b...   269   5e-71
UniRef50_UPI00019771AF Nitrilase/cyanide hydratase and apolipopr...   269   7e-71
UniRef50_B6B254 Hydrolase in PqqF 5'region n=1 Tax=Rhodobacteral...   269   7e-71
UniRef50_D0LZ94 Nitrilase/cyanide hydratase and apolipoprotein N...   269   7e-71
UniRef50_C1E770 Predicted protein (Fragment) n=1 Tax=Micromonas ...   269   9e-71
UniRef50_C8S929 Nitrilase/cyanide hydratase and apolipoprotein N...   268   1e-70
UniRef50_Q6C005 YALI0F29139p n=1 Tax=Yarrowia lipolytica RepID=Q...   268   1e-70
UniRef50_A4XQL4 Nitrilase/cyanide hydratase and apolipoprotein N...   268   1e-70
UniRef50_A3WPW5 Predicted amidohydrolase, nitrilase family proti...   268   1e-70
UniRef50_A0LQU6 Nitrilase/cyanide hydratase and apolipoprotein N...   267   2e-70
UniRef50_A1SU00 Nitrilase/cyanide hydratase and apolipoprotein N...   267   3e-70
UniRef50_A8PU96 Putative uncharacterized protein n=1 Tax=Malasse...   266   4e-70
UniRef50_Q6SHH5 Carbon-nitrogen hydrolase family protein n=2 Tax...   266   4e-70
UniRef50_A8ZSH3 Nitrilase/cyanide hydratase and apolipoprotein N...   266   4e-70
UniRef50_C9RPM3 Nitrilase/cyanide hydratase and apolipoprotein N...   266   4e-70
UniRef50_B1K4S5 Nitrilase/cyanide hydratase and apolipoprotein N...   266   5e-70
UniRef50_Q6L0F7 Carbon-nitrogen hydrolase family n=1 Tax=Picroph...   266   6e-70
UniRef50_D1VW19 Hydrolase C26A3.11 n=1 Tax=Peptoniphilus lacrima...   266   6e-70
UniRef50_A6TPX2 Nitrilase/cyanide hydratase and apolipoprotein N...   266   7e-70
UniRef50_A8RJL1 Putative uncharacterized protein n=1 Tax=Clostri...   266   7e-70
UniRef50_UPI0001AEF4A9 hypothetical protein SghaA1_01010 n=1 Tax...   266   8e-70
UniRef50_A0JSW0 Nitrilase/cyanide hydratase and apolipoprotein N...   266   8e-70
UniRef50_B8FEV8 Nitrilase/cyanide hydratase and apolipoprotein N...   265   9e-70
UniRef50_A1SE99 Nitrilase/cyanide hydratase and apolipoprotein N...   265   1e-69
UniRef50_A8LPZ9 Nitrilase/cyanide hydratase and apolipoprotein N...   265   1e-69
UniRef50_C7LN61 Nitrilase/cyanide hydratase and apolipoprotein N...   265   1e-69
UniRef50_Q1YMV3 Putative hydratase n=1 Tax=Aurantimonas manganox...   265   1e-69
UniRef50_A6VWN8 Nitrilase/cyanide hydratase and apolipoprotein N...   264   1e-69
UniRef50_A4SNH5 Amidohydrolase family protein n=2 Tax=Proteobact...   264   2e-69
UniRef50_B8D189 Nitrilase/cyanide hydratase n=1 Tax=Halothermoth...   264   2e-69
UniRef50_C6CAD7 Nitrilase/cyanide hydratase and apolipoprotein N...   264   2e-69
UniRef50_Q15ZG7 Nitrilase/cyanide hydratase and apolipoprotein N...   264   3e-69
UniRef50_Q11M91 Nitrilase/cyanide hydratase and apolipoprotein N...   264   3e-69
UniRef50_O94660 Probable hydrolase nit2 n=2 Tax=Schizosaccharomy...   263   3e-69
UniRef50_D2VM50 Predicted protein n=1 Tax=Naegleria gruberi RepI...   263   5e-69
UniRef50_B0X5I4 Hydrolase n=5 Tax=Culicidae RepID=B0X5I4_CULQU        263   5e-69
UniRef50_B4RQA3 Nitrilase n=28 Tax=Neisseriaceae RepID=B4RQA3_NEIG2   263   5e-69
UniRef50_A7FDR9 Hydrolase, carbon-nitrogen family protein n=45 T...   263   5e-69
UniRef50_C9RT97 Nitrilase/cyanide hydratase and apolipoprotein N...   262   1e-68
UniRef50_Q2NAB0 Nitrilase 1 like protein n=3 Tax=Sphingomonadale...   261   2e-68
UniRef50_A4J6K3 Nitrilase/cyanide hydratase and apolipoprotein N...   261   2e-68
UniRef50_D2RHR5 Nitrilase/cyanide hydratase and apolipoprotein N...   261   2e-68
UniRef50_Q0VS65 Carbon-nitrogen hydrolase family protein n=2 Tax...   261   2e-68
UniRef50_O59829 Probable nitrilase C965.09 n=2 Tax=cellular orga...   260   3e-68
UniRef50_Q972X1 264aa long hypothetical beta-ureidopropionase n=...   260   3e-68
UniRef50_A0PVY5 Amidohydrolase n=12 Tax=Actinomycetales RepID=A0...   260   4e-68
UniRef50_B9JB81 Amidohydrolase protein n=4 Tax=cellular organism...   259   7e-68
UniRef50_Q9Y9L1 Putative hydrolase n=1 Tax=Aeropyrum pernix RepI...   259   8e-68
UniRef50_C7QIS9 Nitrilase/cyanide hydratase and apolipoprotein N...   259   1e-67
UniRef50_UPI0001973219 Nitrilase/cyanide hydratase and apolipopr...   258   1e-67
UniRef50_C6B8T0 Nitrilase/cyanide hydratase and apolipoprotein N...   258   1e-67
UniRef50_C8NJS3 Carbon-nitrogen hydrolase family protein n=16 Ta...   258   1e-67
UniRef50_Q8TLM7 Carbon-nitrogen hydrolase n=2 Tax=Methanosarcina...   258   1e-67
UniRef50_C0VX65 Nitrilase/cyanide hydratase and apolipoprotein N...   258   1e-67
UniRef50_C7GZE3 Nitrilase protein n=1 Tax=Eubacterium saphenum A...   258   2e-67
UniRef50_A8SQH9 Putative uncharacterized protein n=1 Tax=Coproco...   257   2e-67
UniRef50_C9N4S0 Nitrilase/cyanide hydratase and apolipoprotein N...   257   2e-67
UniRef50_B1L5H4 Nitrilase/cyanide hydratase and apolipoprotein N...   257   2e-67
UniRef50_Q5UF08 Predicted amidohydrolase n=1 Tax=uncultured alph...   257   2e-67
UniRef50_B2HTJ8 Predicted amidohydrolase n=18 Tax=Acinetobacter ...   257   4e-67
UniRef50_B1MI91 Hypothetical carbon-nitrogen hydrolase family pr...   257   4e-67
UniRef50_Q2RWF2 Nitrilase/cyanide hydratase and apolipoprotein N...   257   4e-67
UniRef50_P55176 UPF0012 hydrolase in pqqF 5'region n=22 Tax=Bact...   256   4e-67
UniRef50_C5BHY1 N-carbamoylputrescine amidase n=3 Tax=Bacteria R...   256   4e-67
UniRef50_A0BLB1 Chromosome undetermined scaffold_114, whole geno...   256   4e-67
UniRef50_C5BSY0 Hydrolase, carbon-nitrogen family n=1 Tax=Teredi...   256   4e-67
UniRef50_D2RK67 Nitrilase/cyanide hydratase and apolipoprotein N...   256   5e-67
UniRef50_P47016 Probable hydrolase NIT2 n=9 Tax=Saccharomycetace...   256   5e-67
UniRef50_D1UMG3 Nitrilase/cyanide hydratase and apolipoprotein N...   256   6e-67
UniRef50_C0F0M8 Putative uncharacterized protein n=1 Tax=Eubacte...   256   7e-67
UniRef50_Q3IFH8 Putative hydrolase, carbon-nitrogen family n=3 T...   255   1e-66
UniRef50_D0RND5 Hydrolase n=1 Tax=alpha proteobacterium HIMB114 ...   255   1e-66
UniRef50_A6CCB9 Predicted amidohydrolase n=1 Tax=Planctomyces ma...   255   1e-66
UniRef50_A7I462 Hydrolase in agr operon (ORF 5) n=1 Tax=Campylob...   255   1e-66
UniRef50_A6UC57 Nitrilase/cyanide hydratase and apolipoprotein N...   255   1e-66
UniRef50_B7CB92 Putative uncharacterized protein n=1 Tax=Eubacte...   255   1e-66
UniRef50_Q89413 A78R protein n=7 Tax=root RepID=Q89413_PBCV1          255   1e-66
UniRef50_C7QHA6 Nitrilase/cyanide hydratase and apolipoprotein N...   255   1e-66
UniRef50_A6UCF8 Nitrilase/cyanide hydratase and apolipoprotein N...   255   1e-66
UniRef50_C9D316 Hydrolase n=1 Tax=Silicibacter sp. TrichCH4B Rep...   254   2e-66
UniRef50_C1B562 Putative hydrolase n=2 Tax=Actinomycetales RepID...   254   2e-66
UniRef50_A5GU42 Nitrilase-related protein n=1 Tax=Synechococcus ...   254   2e-66
UniRef50_Q47VH0 Hydrolase, carbon-nitrogen family n=1 Tax=Colwel...   254   2e-66
UniRef50_A6DN63 Nitrilase/cyanide hydratase and apolipoprotein N...   254   3e-66
UniRef50_C6HVQ6 Putative carbon-nitrogen hydrolase n=1 Tax=Lepto...   254   3e-66
UniRef50_Q1MYM0 Predicted amidohydrolase n=1 Tax=Bermanella mari...   253   3e-66
UniRef50_A9UWV2 Predicted protein (Fragment) n=1 Tax=Monosiga br...   253   4e-66
UniRef50_B7G2G6 Predicted protein n=1 Tax=Phaeodactylum tricornu...   253   4e-66
UniRef50_A8MC40 Nitrilase/cyanide hydratase and apolipoprotein N...   253   5e-66
UniRef50_D0XIR2 Nitrilase/cyanide hydratase and apolipoprotein N...   252   7e-66
UniRef50_Q46E33 Carbon-nitrogen hydrolase n=3 Tax=Methanosarcina...   252   7e-66
UniRef50_A4BGL8 Predicted amidohydrolase n=1 Tax=Reinekea blande...   252   1e-65
UniRef50_A5TTZ3 Possible amidohydrolase n=4 Tax=Fusobacterium Re...   252   1e-65
UniRef50_B4D6H9 Nitrilase/cyanide hydratase and apolipoprotein N...   251   1e-65
UniRef50_A1RVM3 Nitrilase/cyanide hydratase and apolipoprotein N...   251   1e-65
UniRef50_C2D0V8 Possible N-carbamoylputrescine amidase n=1 Tax=L...   251   1e-65
UniRef50_A7H2U5 Carbon-nitrogen hydrolase n=5 Tax=Campylobactera...   251   2e-65
UniRef50_Q6AMZ4 Putative uncharacterized protein n=1 Tax=Desulfo...   250   3e-65
UniRef50_A5C5V4 Putative uncharacterized protein n=1 Tax=Vitis v...   250   3e-65
UniRef50_A7I641 Nitrilase/cyanide hydratase and apolipoprotein N...   250   4e-65
UniRef50_Q6MPB5 Putative amidohydrolase n=1 Tax=Bdellovibrio bac...   250   5e-65
UniRef50_Q4K6V5 Carbon-nitrogen hydrolase family protein n=3 Tax...   249   6e-65
UniRef50_A0B689 Nitrilase/cyanide hydratase and apolipoprotein N...   249   7e-65
UniRef50_A6TL48 Nitrilase/cyanide hydratase and apolipoprotein N...   249   9e-65
UniRef50_B0MXF9 Putative uncharacterized protein n=1 Tax=Alistip...   248   1e-64
UniRef50_C8PKQ1 Nitrilase/cyanide hydratase and apolipoprotein N...   247   2e-64
UniRef50_C6QR30 Nitrilase/cyanide hydratase and apolipoprotein N...   247   3e-64

Sequences not found previously or not previously below threshold:

>UniRef50_Q28IE5 Omega-amidase NIT2 n=42 Tax=cellular organisms RepID=NIT2_XENTR
          Length = 276

 Score =  343 bits (880), Expect = 4e-93,   Method: Composition-based stats.
 Identities = 75/272 (27%), Positives = 122/272 (44%), Gaps = 15/272 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             ++  QF V+ V  +N      L+ +AA+  A + ALPE   +          + A+ +
Sbjct: 4   FRLSLVQFLVSPVKSENLNRACKLIKEAAQKGAQIVALPECFNSPY--GTKYFPEYAEKI 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD---- 115
            GE   RL + +K   +  I         G+ +N   V    G ++ ++ K+HL+D    
Sbjct: 62  PGESTERLSQVAKECGIYLIGGSIPEEDSGKLYNTCAVFGPDGTLLVKHRKIHLFDIDVP 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                QES  +  G+    + E    KVG+  CYD+RF ELA   + +G ++LV P A+ 
Sbjct: 122 GKIRFQESETLSPGDS-FSVFETPYCKVGVGICYDIRFAELAQLYSKKGCQLLVYPGAFN 180

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  L  ARALD   Y+  A    ++       G S I+ P+G  IA A    
Sbjct: 181 M-TTGPAHWELLQRARALDNQVYVATASPARDEKASYVAWGHSTIVSPWGEVIAKAGSEE 239

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            +I A++  E + ++R Q+P+   RR     +
Sbjct: 240 TVISADIDLEYLAEIREQIPIRRQRRHDLYSV 271


>UniRef50_Q9NQR4 Omega-amidase NIT2 n=88 Tax=Eukaryota RepID=NIT2_HUMAN
          Length = 276

 Score =  337 bits (866), Expect = 2e-91,   Method: Composition-based stats.
 Identities = 69/270 (25%), Positives = 122/270 (45%), Gaps = 15/270 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +A  Q  ++S+   N     S + +AA   A + +LPE   +     A    + A+ +
Sbjct: 4   FRLALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFNSPY--GAKYFPEYAEKI 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAKLHLYD---- 115
            GE   +L   +K   +  I         G+ +N   V    G ++A+Y K+HL+D    
Sbjct: 62  PGESTQKLSEVAKECSIYLIGGSIPEEDAGKLYNTCAVFGPDGTLLAKYRKIHLFDIDVP 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                QES+ +  G+      +    +VGL  CYD+RF ELA   A +G ++LV P A+ 
Sbjct: 122 GKITFQESKTLSPGDS-FSTFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFN 180

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  L  +RA+D   Y+  A    +        G S +++P+G  +A A    
Sbjct: 181 L-TTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKAGTEE 239

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           A++ +++  +++ ++R Q+PV   +R    
Sbjct: 240 AIVYSDIDLKKLAEIRQQIPVFRQKRSDLY 269


>UniRef50_C0Z4R2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z4R2_BREBN
          Length = 265

 Score =  333 bits (854), Expect = 4e-90,   Method: Composition-based stats.
 Identities = 95/263 (36%), Positives = 140/263 (53%), Gaps = 4/263 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDAD-LSVKSAQL 59
           M VA  Q   T    +N +  A  +A+A    A    LPE   A     +     + A+ 
Sbjct: 1   MKVAIAQLTATMDKTQNLQKAADYIAKAKAAGADFVILPEMYSAPATPKSGVTPAEVAEK 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVALQA-GNIVARYAKLHLYDA 116
           L+G F+  L   +  + +  +  +         RA+N  V L   G ++  Y K HLYDA
Sbjct: 61  LDGPFVSGLAELASEHGVYVVCGVFESIEGDENRAYNTTVFLGREGQLLHAYRKTHLYDA 120

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
           F+  ES  +  G+    ++E E  K+GLM CY++RFPE+A   ALQGA+IL +PA WV G
Sbjct: 121 FSYTESDFIAPGDNPYQVVETEFGKIGLMVCYEVRFPEIARQFALQGADILFVPAGWVAG 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
            +KE HW TL+ ARA++ T ++ AA + GN   G+S  +DP GV IA+A E   L++ E+
Sbjct: 181 AMKEDHWETLVRARAIENTMFVCAADQVGNIFAGRSMFVDPMGVVIASAGEEETLLVTEL 240

Query: 237 TPERVRQVRAQLPVLNNRRFAPP 259
              R+ +VR +LP + NRR    
Sbjct: 241 DVSRIERVRGKLPSVANRRAELY 263


>UniRef50_C8VW38 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Clostridia RepID=C8VW38_DESAS
          Length = 285

 Score =  326 bits (836), Expect = 6e-88,   Method: Composition-based stats.
 Identities = 74/277 (26%), Positives = 124/277 (44%), Gaps = 20/277 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL- 59
              A  Q  V+     N     S++ +A    A L  +PE        +       A+  
Sbjct: 3   FKTAVCQMLVSHSKSDNISKAKSMIEEAVSQGAELIIMPEMFNCPY--ENTSFPDFAESY 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVP----STPGRAWNMLVALQA-GNIVARYAKLHLY 114
            +GE +  L + +K N +  +           +  + +N        G ++ R+ K+HL+
Sbjct: 61  PDGETVKFLAQTAKENKIYLVGGSVPESAETESGRQIFNTSFFFDPQGQLIVRHRKVHLF 120

Query: 115 D-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
           D       + +ES  +  G++I  +   +   +GL  CYD+RFPEL  A  L+GA+++++
Sbjct: 121 DIDIEGGISFRESDTLGRGDQI-TVAGTKWCDIGLAICYDMRFPELMRAMVLKGAKMILI 179

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAA 224
           PAA+        HW   L  RA+D   +++AA    N        G S I+DP+G  +A 
Sbjct: 180 PAAFNT-TTGPAHWEITLKTRAVDNQTFVIAASPARNLEAAYHAYGHSLIVDPWGEILAE 238

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           A     +I A +  E V +VR QLP+L +RR    +L
Sbjct: 239 AGTGEEIIYASIDLELVDRVRRQLPLLRHRRTDLYRL 275


>UniRef50_B9L3Z7 Hydrolase, carbon-nitrogen family protein n=8 Tax=Bacteria
           RepID=B9L3Z7_THERP
          Length = 279

 Score =  323 bits (830), Expect = 3e-87,   Method: Composition-based stats.
 Identities = 86/273 (31%), Positives = 130/273 (47%), Gaps = 17/273 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +   Q    S   +N  +   L+ +AA   A L ALPE +        +L   +A+ +
Sbjct: 5   LRIGLVQMNSRSDKSENLAVAERLIEEAARQGAELVALPEYVNFLGP--RELHEANAEPI 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPST--PGRAWNMLVAL-QAGNIVARYAKLHLYDA- 116
            G    R    ++R  +  +    +  +  PG+ +N  V     G I+A Y K+HL+D  
Sbjct: 63  PGPTTERFAALARRYGIYLLGGSILERSAIPGKYYNTSVLFAPDGEIIASYRKIHLFDVD 122

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                   ES  +  G+ +    EV G  VGL  CYDLRFPEL    AL GAE++++PAA
Sbjct: 123 LTGNVTSNESATILPGDRVVT-AEVAGHVVGLTICYDLRFPELYRLLALDGAELILVPAA 181

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +      + HW TLL ARA++  CY+ A  + G  +      G S + DP+G  IA A  
Sbjct: 182 FTL-YTGKDHWHTLLRARAIENQCYVAAPAQIGPHDPGQQCYGHSLVADPWGTVIAEAIN 240

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
              +++  +    +R+VRAQLP L NRR     
Sbjct: 241 RVGVVVTTLDFAYLREVRAQLPSLANRRPETYG 273


>UniRef50_B9ZGS1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Natrialba magadii ATCC 43099 RepID=B9ZGS1_NATMA
          Length = 271

 Score =  323 bits (830), Expect = 3e-87,   Method: Composition-based stats.
 Identities = 86/272 (31%), Positives = 136/272 (50%), Gaps = 17/272 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +AA Q       E N       + +AA+  A + +LPE        + +     A+ +
Sbjct: 4   FTIAACQMDSQDDKEANLTQALDFIDEAAQKGADVVSLPEMFSFMG--EKEAYSTHAEPV 61

Query: 61  EGEFLGRLRRESKRNMMTTI-LTIHVPSTPG-RAWNMLVALQA-GNIVARYAKLHLYDAF 117
            GE    L  ++  + +     +    +  G R +N  V +   G I A+Y K HL+D  
Sbjct: 62  PGETTAALADKATTHGLHVHSGSFFEKAGDGDRVYNTSVVIDPDGEIQAQYRKTHLFDVT 121

Query: 118 -----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  QES+ V  G++   ++E +    GL  CYDLRF EL  + A+QGAE+L +PAA
Sbjct: 122 IGDEVVTQESKHVAPGDD-VTVVETDLATFGLSVCYDLRFSELYRSMAMQGAEVLFVPAA 180

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++T CY+VAAG+ G+K     + G+S IIDP+G  I  AS+
Sbjct: 181 FTL-FTGKDHWLPLLKARAIETQCYVVAAGQIGDKPSSVPSFGKSVIIDPWGNVIRMASD 239

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
              ++ AEV  + + +VR ++P L ++R    
Sbjct: 240 REEVVTAEVDLDYLAEVRQKIPCLEHKRDELY 271


>UniRef50_C6CYG4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Bacillales RepID=C6CYG4_PAESJ
          Length = 270

 Score =  321 bits (825), Expect = 1e-86,   Method: Composition-based stats.
 Identities = 76/267 (28%), Positives = 123/267 (46%), Gaps = 15/267 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAEN--DASLFALPEALLARDDHDADLSVKSA 57
           + +A  Q  +     E N    +S++ +AA       +   PE                A
Sbjct: 11  LRIALLQMNIEVGQPEANFSKLSSMLEEAASQPNKPDVIVFPEMWNTGYAL--TEITTLA 68

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLV-ALQAGNIVARYAKLHLYDA 116
                     L   S+++ +  I            +N +    + GN +  Y+K+HL+  
Sbjct: 69  DPNGERTKAYLTEFSRKHGIHIIAGSIAEGREDGVYNTIYAFDREGNQIGDYSKIHLFRL 128

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
             + E + + AG+++  L E+EG   G+M CYD+RFPELA   AL GA++L +PA W   
Sbjct: 129 --MDEEKYLAAGDKLGKL-EIEGAGAGMMICYDIRFPELARKLALDGAKLLFVPAEWPHP 185

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALI 232
             + HHW TLL ARA++   +++A    G        G S ++DP+G TIA A E   ++
Sbjct: 186 --RLHHWRTLLTARAIENQMFVIACNRVGISGDTHFFGHSMVLDPWGETIAEAGEEETIL 243

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPP 259
            AE+    V  VR ++PV  +RR +  
Sbjct: 244 YAEIDLSLVDTVRGKIPVFEDRRPSLY 270


>UniRef50_A1HPP3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HPP3_9FIRM
          Length = 259

 Score =  320 bits (822), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 76/266 (28%), Positives = 126/266 (47%), Gaps = 14/266 (5%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q   V    E N +   +++ Q A+  A LF LPE          D  +K  + 
Sbjct: 1   MKVALLQMDIVLGDVEANRQKALAMLEQGAKAGAKLFVLPELWTTGYVL--DQLLKIGEP 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
             G  +  L++ +K N +  +         G+ +N +  + + G +V +Y+K+HL     
Sbjct: 59  DGGPTVKMLQQFAKDNGVEIVGGSIAEIRDGKVYNTIYVIDSAGEVVGKYSKIHL--VPM 116

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E + +  G+    L ++   K G + CYDLRF EL  A AL+GAE+L +PA W     
Sbjct: 117 MDEEKYLTPGDRQG-LFDLSFGKAGGIVCYDLRFTELTRALALKGAEVLFIPAEWPAIRG 175

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASE-MPALIM 233
           +  HW  L  ARA++   ++VA    G        G S ++ P+G  +A  SE    +I+
Sbjct: 176 R--HWLILSQARAIENQMFVVAVNRVGRDHNNTFFGHSLVVSPWGEVLAEGSETEEQVII 233

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAPP 259
           A++    V ++R ++PV  +RR    
Sbjct: 234 ADIDLGMVPEIRRKVPVFADRRPQYY 259


>UniRef50_A5N8H1 Predicted hydrolase n=3 Tax=Clostridium RepID=A5N8H1_CLOK5
          Length = 275

 Score =  318 bits (815), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 67/276 (24%), Positives = 120/276 (43%), Gaps = 19/276 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +   Q  V  S    N +     + +AA     + ALPE        +     + A+ 
Sbjct: 1   MKIGLCQMMVLKSSKSDNVKRAKEAIYKAANKGTDIVALPEMFNCYY--NTKYFREYAEK 58

Query: 60  LE--GEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQ-AGNIVARYAKLHLYD 115
            +  GE L  L   +K   +  +          G  +N        G ++ ++ K+HL+D
Sbjct: 59  DDCKGETLSMLSSAAKEMGIYIVGGSIPEIDDKGNIYNTSFVFNEKGELIGKHRKMHLFD 118

Query: 116 -----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                    +ES  +  G++   +++ +  K+G+  CYD+RFPEL    ALQGA+I+ +P
Sbjct: 119 IDIKDKITFKESNVLTPGDK-VTVIDTKWGKIGVAICYDVRFPELMRLMALQGAKIIFIP 177

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAA 225
           A++        HW  L  + A++   Y V      N N      G S ++DP+G  +   
Sbjct: 178 ASFNT-TTGPSHWELLFRSAAVENQLYTVGISPARNINYSYVAYGNSLVVDPWGKILNIL 236

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            E   ++++E+  E + +VR  +PV  +RR    ++
Sbjct: 237 DEKEGILLSEIDLEYIYEVRKSIPVFEHRREDLYEI 272


>UniRef50_B9HD27 Predicted protein n=8 Tax=Magnoliophyta RepID=B9HD27_POPTR
          Length = 370

 Score =  318 bits (815), Expect = 2e-85,   Method: Composition-based stats.
 Identities = 69/278 (24%), Positives = 114/278 (41%), Gaps = 20/278 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +   Q +VT+  E+N       + +AA   A L  LPE   +   +  D     A+ +
Sbjct: 88  FKIGLCQLSVTADKERNIAHARKAIEEAAAKGAKLVMLPEIWNSPYSN--DCFPVYAEDI 145

Query: 61  E-----GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLY 114
           +           L   +    +T +       +  R +N   V    G + A++ K+HL+
Sbjct: 146 DAGGEASPSTAMLSEAAGLLKVTIVGGSIPERSGDRLYNTCCVFDSDGKLKAKHRKIHLF 205

Query: 115 D-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
           D          ES+ + AG     +++ E  ++G+  CYD+RF ELA+  A +GA ++  
Sbjct: 206 DIDIPGKITFIESKTLTAGETP-TIVDTEVGRIGIGICYDIRFQELAIIYAARGAHLICY 264

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAA 224
           P A+        HW  L  ARA D   Y+           G    G S ++ PFG  +A 
Sbjct: 265 PGAFNM-TTGPLHWELLQRARAADNQLYVATCSPARDVAAGYVAWGHSTLVGPFGEVLAT 323

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
                 +I+AE+    +   R  LP+   RR    QL+
Sbjct: 324 TEHEEDIIIAEIDYSLLEVRRTNLPLTKQRRGDLYQLV 361


>UniRef50_Q8RUF8 AT5g12040/F14F18_210 n=16 Tax=Eukaryota RepID=Q8RUF8_ARATH
          Length = 369

 Score =  317 bits (813), Expect = 2e-85,   Method: Composition-based stats.
 Identities = 75/278 (26%), Positives = 118/278 (42%), Gaps = 20/278 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +   Q +VTS  ++N       + +AA   A L  LPE   +   +D+      A+ +
Sbjct: 88  FNIGLCQLSVTSDKKRNISHAKKAIEEAASKGAKLVLLPEIWNSPYSNDS--FPVYAEEI 145

Query: 61  E-----GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLY 114
           +           L   SKR  +T I          R +N   V    G + A++ K+HL+
Sbjct: 146 DAGGDASPSTAMLSEVSKRLKITIIGGSIPERVGDRLYNTCCVFGSDGELKAKHRKIHLF 205

Query: 115 D-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
           D          ES+ + AG     +++ +  ++G+  CYD+RF ELA+  A +GA +L  
Sbjct: 206 DIDIPGKITFMESKTLTAGETP-TIVDTDVGRIGIGICYDIRFQELAMIYAARGAHLLCY 264

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAA 224
           P A+        HW  L  ARA D   Y+           G    G S ++ PFG  +A 
Sbjct: 265 PGAFNM-TTGPLHWELLQRARATDNQLYVATCSPARDSGAGYTAWGHSTLVGPFGEVLAT 323

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
                A+I+AE+    + Q R  LP+   RR    QL+
Sbjct: 324 TEHEEAIIIAEIDYSILEQRRTSLPLNRQRRGDLYQLV 361


>UniRef50_Q7TQ94 Nitrilase homolog 1 n=6 Tax=Coelomata RepID=NIT1_RAT
          Length = 292

 Score =  315 bits (809), Expect = 7e-85,   Method: Composition-based stats.
 Identities = 88/274 (32%), Positives = 136/274 (49%), Gaps = 18/274 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q   T   ++N + CA L+ +A    A L  LPEA      + A+  +  ++ L+G
Sbjct: 14  VAVCQVTSTPNKQENFKTCAELVQEATRLGACLAFLPEAFDFIARNPAETLL-LSEPLDG 72

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG-----RAWNMLVALQ-AGNIVARYAKLHLYDA 116
           + LG+  + ++   +   L              + +N  V L   G++VA Y K HL D 
Sbjct: 73  DLLGQYSQLARECGIWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGSVVASYRKTHLCDV 132

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                  ++ES     G  + P ++    KVGL  CYD+RFPEL+L  A  GAEIL  P+
Sbjct: 133 EIPGQGPMRESNYTMPGYALEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPS 192

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS 226
           A+        HW  LL ARA+++ CY++AA +CG  +      G S ++DP+G  +A+ S
Sbjct: 193 AFG-SVTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPWGTVVASCS 251

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           E P L +A +    ++Q+R  LPV  +RR     
Sbjct: 252 EGPGLCLARIDLHFLQQMRQHLPVFQHRRPDLYG 285


>UniRef50_UPI0001924654 PREDICTED: similar to Nit protein 1 n=1 Tax=Hydra magnipapillata
           RepID=UPI0001924654
          Length = 303

 Score =  313 bits (803), Expect = 4e-84,   Method: Composition-based stats.
 Identities = 77/271 (28%), Positives = 131/271 (48%), Gaps = 15/271 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  Q   T   E+N  IC  L+ ++ + +A +  LPE      ++  D   K A+ LE
Sbjct: 27  RVAVCQMNSTDDKERNIRICTELINESYDKEAKIVFLPECFDYIAENKTDSV-KMAESLE 85

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPS---TPGRAWNMLVALQ-AGNIVARYAKLHLYD-- 115
           G+ +   +  +K   +   +         + G  +N  + +   G +V+ Y K+HL+D  
Sbjct: 86  GDIIKHYKNLAKEKSLWLSMGGFHEKCSTSDGSIFNSHIIINANGELVSVYRKVHLFDVD 145

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                ++ES  V  G +I   ++    K+GL+ CYDLRFPE+++     GA+IL  P+A+
Sbjct: 146 IPGTVLKESSYVTPGKKIEKPVDTPVGKIGLLCCYDLRFPEISIVNRQLGAQILTFPSAF 205

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW  LL ARA++  CY++AA + G  N      G + I+DP+G  +A   + 
Sbjct: 206 TF-TTGLAHWHVLLRARAIENQCYVIAAAQTGKHNDKRTSYGHALIVDPWGKVVAECEKE 264

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             + +A +    V  +R  +PV  +RR+   
Sbjct: 265 NGVCVASIDLSLVDSIRESMPVFEHRRYDLY 295


>UniRef50_Q86X76 Nitrilase homolog 1 n=34 Tax=Eumetazoa RepID=NIT1_HUMAN
          Length = 327

 Score =  312 bits (801), Expect = 7e-84,   Method: Composition-based stats.
 Identities = 90/274 (32%), Positives = 129/274 (47%), Gaps = 18/274 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q   T   ++N + CA L+ +AA   A L  LPEA       D   ++  ++ L G
Sbjct: 49  VAVCQVTSTPDKQQNFKTCAELVREAARLGACLAFLPEAFDFI-ARDPAETLHLSEPLGG 107

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG-----RAWNMLVALQ-AGNIVARYAKLHLYDA 116
           + L    + ++   +   L              + +N  V L   G +VA Y K HL D 
Sbjct: 108 KLLEEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDV 167

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                  + ES     G  +   +     K+GL  CYD+RFPEL+LA A  GAEIL  P+
Sbjct: 168 EIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPS 227

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS 226
           A+        HW  LL ARA++T CY+VAA +CG  +      G S ++DP+G  +A  S
Sbjct: 228 AFGSIT-GPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCS 286

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           E P L +A +    +RQ+R  LPV  +RR     
Sbjct: 287 EGPGLCLARIDLNYLRQLRRHLPVFQHRRPDLYG 320


>UniRef50_C1TRG7 Predicted amidohydrolase n=1 Tax=Dethiosulfovibrio peptidovorans
           DSM 11002 RepID=C1TRG7_9BACT
          Length = 274

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 83/271 (30%), Positives = 131/271 (48%), Gaps = 15/271 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VAA Q       E N     +++ +A +  ASL   PE                A+ + 
Sbjct: 5   TVAAAQMDSGPEKEINLIHMETMIEEAGKRGASLVVFPE-TSTLLPSSGIEKEAGAEPVP 63

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYD--- 115
           G    RL + ++   +       +    G  + +N  V +   G + A+Y K+HL+D   
Sbjct: 64  GPSTDRLSKAAREAGIWVHSGSLLERIEGNEKCYNTSVLISPEGEVTAKYRKIHLFDVNV 123

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               +++ES    +GNEI  + E     +G+  CYDLRFPEL    AL+GA++LV+PA +
Sbjct: 124 HDGPSVRESASYASGNEIV-IAETPLGNIGMSICYDLRFPELYRILALRGAQVLVVPACF 182

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMP 229
                KE HW  LL ARA++  CY+VA G+ G+    +  G+S ++DP+G   A  +   
Sbjct: 183 TSDTGKE-HWDPLLRARAIENLCYVVAPGQVGSKPRYRAHGKSMVVDPWGTVTACRASGE 241

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            L++AEV  +R+  +R  +P L NRR     
Sbjct: 242 GLVLAEVDLDRLESLRHSVPCLQNRRPDTYD 272


>UniRef50_UPI000197C0D6 hypothetical protein PretD1_21713 n=1 Tax=Providencia rettgeri DSM
           1131 RepID=UPI000197C0D6
          Length = 263

 Score =  309 bits (793), Expect = 6e-83,   Method: Composition-based stats.
 Identities = 90/263 (34%), Positives = 141/263 (53%), Gaps = 4/263 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDAD-LSVKSAQL 59
           M +A  Q A +     N +     + +AA+  A L  LPE  +A    D+       A+ 
Sbjct: 1   MKIAIAQLASSPDKALNLKKACEAIQKAAQGGADLVLLPEMFMAFVPADSGISYADVAEP 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYDA 116
           ++G F+ +L + +++  +     I+  +     RA+N  + L   G ++  Y K HLYDA
Sbjct: 61  VDGPFVSQLAKAAQQYGIYVTCGIYESAPNEPKRAFNTTIMLNRQGELIYHYQKTHLYDA 120

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
           F+ QES  +   N     +E E  K+G++ CY+LRFPE+A    L GA+++++P AWV G
Sbjct: 121 FSYQESLNIIQSNNELKPVETEFGKIGVLVCYELRFPEVARKLTLAGADLILVPTAWVSG 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
           PLKE H+ TL+ ARAL+ T  + A  + GN  IG+S + D  GVTIA+A     L  AE+
Sbjct: 181 PLKEEHYQTLVKARALENTVPVCACDQTGNIFIGRSLVCDALGVTIASAGYDETLFFAEI 240

Query: 237 TPERVRQVRAQLPVLNNRRFAPP 259
           + +   + R +LP + NRR    
Sbjct: 241 STQHTAETREKLPCMQNRRPELY 263


>UniRef50_UPI000186DBB5 conserved hypothetical protein n=1 Tax=Pediculus humanus corporis
           RepID=UPI000186DBB5
          Length = 438

 Score =  309 bits (792), Expect = 8e-83,   Method: Composition-based stats.
 Identities = 86/270 (31%), Positives = 138/270 (51%), Gaps = 15/270 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q   T+  EKN +I  SL+ +A + +A +  LPEA        A+     A+ L+G
Sbjct: 7   IAICQMTSTNDKEKNFQIVESLVTEAKKANAKIAFLPEACDFVGSSKAETIT-LAETLDG 65

Query: 63  EFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF--- 117
             + + +  +K   +   +  IH   T  + +N  + +   GNIV +Y+K+HL+D     
Sbjct: 66  PLVAKYKNLAKSLKIWISLGGIHESYTKSKLYNTHLMINDQGNIVGKYSKIHLFDVEIPE 125

Query: 118 ---AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               + ES  V+ G  I   +      VGL  CYD+RF EL++  A  GA+IL  P+A+ 
Sbjct: 126 QNVRLMESSYVEKGKSITNPISTPVGNVGLAICYDMRFSELSIVLARLGAQILTFPSAFT 185

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMP 229
                  HW T+L ARA++T CY+VAA + G+ N      G S ++DP+G  IA  S+ P
Sbjct: 186 FAT-GASHWETILKARAVETQCYVVAAAQVGSHNDKRTSWGHSMVVDPWGKIIAQCSDGP 244

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            + +  +    + +VR  +PV N+RR+   
Sbjct: 245 GIAVTSININYLEKVRLSMPVWNHRRYDLY 274


>UniRef50_A9A651 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Thaumarchaeota RepID=A9A651_NITMS
          Length = 268

 Score =  309 bits (792), Expect = 8e-83,   Method: Composition-based stats.
 Identities = 82/266 (30%), Positives = 141/266 (53%), Gaps = 4/266 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQ 58
           M  A  QF  ++  E N +   S + +AA  +A+L A PE                  A+
Sbjct: 1   MKAAVVQFKASTNKETNLKKIISFIEKAASKNATLCAFPEFMMFYTNSSQTPKQLATLAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQA-GNIVARYAKLHLYDA 116
            + G F+  +   +K N +  + + +       R ++    +   G +++ Y K+HLYDA
Sbjct: 61  TINGNFVNTIANTAKENHVQVVGSFYEKSRKKDRVYDTSFVIDKTGKVISTYRKIHLYDA 120

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
              +ES ++ +G++IA  ++    KVG+M CYDLRFPE++ + A  G+E+LV P+AWV+G
Sbjct: 121 LGFRESDKMASGSKIAKPVKTTIGKVGMMICYDLRFPEMSRSLAAAGSEVLVAPSAWVKG 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
            +KE HW T+   RA++  CY++A  + GN   G+S ++DP+G  +    +   +    +
Sbjct: 181 NMKEEHWITINKTRAIENGCYVIAPDQVGNIYCGRSLVVDPYGKILLDMKKKQGIGYVNI 240

Query: 237 TPERVRQVRAQLPVLNNRRFAPPQLL 262
             ++V+Q+R  LP+L NRR      L
Sbjct: 241 DLKKVKQIRKVLPLLKNRRTDIYPTL 266


>UniRef50_Q54JM9 Nitrilase homolog 2 n=1 Tax=Dictyostelium discoideum
           RepID=NIT2_DICDI
          Length = 328

 Score =  306 bits (786), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 65/274 (23%), Positives = 123/274 (44%), Gaps = 17/274 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              A  Q       E+N +     + +AA+N A L +LPE   +          K ++  
Sbjct: 53  FKFAGIQLLCGDNKEENVQNAIKHIDEAAKNGAKLISLPECFNSPYSTST--FEKYSETE 110

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP--STPGRAWNMLVALQA-GNIVARYAKLHLYD-- 115
           +GE + +L   +KRN +  +           G+ +N        G +V ++ K+HL+D  
Sbjct: 111 DGETVKKLSEAAKRNQIFLVGGSIPEIDKATGKIYNTCFIFNDKGEVVKKHRKIHLFDID 170

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES  +  G+    ++++   K+G+  CYD+RFPELA+  +  GA+ L+ P A
Sbjct: 171 VPNKIRFKESETLTPGDS-FSVVDIGYCKIGVAICYDIRFPELAMLYSKMGAKFLIYPGA 229

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASE 227
           +        HW  L   RA+D   ++ A     N     +  G S I++ +G  +A   E
Sbjct: 230 FNM-VTGPAHWELLQRGRAVDNQVFVAAISPARNPSSTYQAWGHSTIVNSWGTILATTDE 288

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             ++I +++    + + R+ +P+ + +R    +L
Sbjct: 289 HQSIIYSDIDLNTLNETRSSIPIYSQKRDDLYKL 322


>UniRef50_Q9HIW8 Nitrilase related protein n=2 Tax=Thermoplasma RepID=Q9HIW8_THEAC
          Length = 270

 Score =  305 bits (782), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 75/264 (28%), Positives = 129/264 (48%), Gaps = 4/264 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLA-RDDHDADLSVKSAQL 59
           M VA  Q   ++  EKN E    L+ +A   ++ L   PE  +        D     ++ 
Sbjct: 1   MKVAVVQMESSTDREKNIEASYRLLEKA--KNSDLVVFPEYQIYAPAFDGKDDMKTISEP 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVALQAGNIVARYAKLHLYDAFA 118
           L+G+F+  +   ++      IL I   +    + +N  + +    ++ +Y KLHL+DAF 
Sbjct: 59  LDGKFVKSITEIARSESQKIILNIPERNQYNLKPFNTAIYIDELGLILKYRKLHLFDAFG 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +ES   + G+    +    G  +G++ CYDLRFPE A   AL GA++++  A W  G  
Sbjct: 119 FRESSVFEKGDARPAIFNGSGDPLGVLICYDLRFPEPARMLALDGAKLIIYQAGWFAGER 178

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K   W TLL ARA++   +++ A + G++  G S +I P+G  +A       +I  ++  
Sbjct: 179 KYDQWKTLLKARAMENGVFVIGAAQTGHRFTGHSMVISPYGDVLAEMGTDEGVITFDIDF 238

Query: 239 ERVRQVRAQLPVLNNRRFAPPQLL 262
             V + R ++PVL +RR     +L
Sbjct: 239 SLVEKYREEVPVLKHRRTDVYDVL 262


>UniRef50_Q2QQ94 Os12g0502500 protein n=5 Tax=Spermatophyta RepID=Q2QQ94_ORYSJ
          Length = 323

 Score =  303 bits (778), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 79/272 (29%), Positives = 124/272 (45%), Gaps = 19/272 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            V   Q       + N   C+ L  +AA +       PE        D +   K A+ L+
Sbjct: 47  RVGVVQMTSVGDLDANYATCSRLAKEAASSGVKFLCFPEVFSFIGSKDGESI-KIAEPLD 105

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPS--TPGRAWNMLVALQA-GNIVARYAKLHLYDA-- 116
           G  + R    +K + M   L             +N  V +   G I + Y K+HL+D   
Sbjct: 106 GPIMQRYCSLAKESSMWLSLGGFQEKGPDDSHQYNTHVLIDDSGEIRSSYRKIHLFDVDV 165

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQG-AEILVLPAA 172
                 +ESR   AG+ +  + +    ++GL  CYDLRFPEL      +  A++L++P+A
Sbjct: 166 PGNMVYKESRFTTAGDTVVAV-DSPFGRLGLTVCYDLRFPELYQCLRFKHQAQVLLVPSA 224

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW  LL ARA++T CY++AA + G  N      G S IIDP+G  IA   +
Sbjct: 225 FTK-VTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDSIIIDPWGTVIARLPD 283

Query: 228 M--PALIMAEVTPERVRQVRAQLPVLNNRRFA 257
                  +A+V   +V  VR ++P+  +R+F 
Sbjct: 284 RLSTGFAVADVDLSKVEAVRTKMPISEHRKFD 315


>UniRef50_Q2NHR0 Predicted amidohydrolase n=1 Tax=Methanosphaera stadtmanae DSM 3091
           RepID=Q2NHR0_METST
          Length = 274

 Score =  303 bits (778), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 69/272 (25%), Positives = 117/272 (43%), Gaps = 13/272 (4%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +A  Q  V    + N E    L+ +A+ N A L  LPE      D ++       +  
Sbjct: 4   FKIATCQMNVVDNKDTNIEHAIQLIKKASSNGAKLITLPEMFNTPYD-NSKFIEYCEEET 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA- 118
             + L  ++  ++   +               +N    +   G I+ ++ K+H++D    
Sbjct: 63  TSKTLNSMQDIAREENIYLQSGSIPEKESNHLYNTAYLINPKGKIIGKHRKMHMFDIDTD 122

Query: 119 ---IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
                ES  +  G+     ++     + +  CYD+RFPEL        ++I++LP A+ +
Sbjct: 123 NMKFTESDTLTPGDS-VTTIKTPLANISIAICYDIRFPELWTLMNKNNSDIILLPGAFNK 181

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPA 230
                 HW TL+ ARA+D  CY+VA      +N      G S I++P+G  IA A E   
Sbjct: 182 -TTGPLHWETLIKARAIDNQCYVVATSPSQIENPYYVAWGHSMIVNPWGKIIAKAHENEE 240

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           ++ A +T   +  VR Q+PVL NRR      +
Sbjct: 241 ILYANITQSSLSSVRNQIPVLTNRRNDIYDTI 272


>UniRef50_D2RIK2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Acidaminococcus RepID=D2RIK2_ACIFE
          Length = 275

 Score =  302 bits (774), Expect = 9e-81,   Method: Composition-based stats.
 Identities = 82/274 (29%), Positives = 126/274 (45%), Gaps = 18/274 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            + AA Q         N       + +AA   A L  LPE++        D++ ++  + 
Sbjct: 4   FIAAAVQMDSQDDKMANLAAAERYIREAAARGARLVVLPESMNYI---GRDMAQEAEAIP 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP---STPGRAWNMLVAL-QAGNIVARYAKLHLYD- 115
            G    RL   ++   +              P R +N    +   G + A+YAKLH +D 
Sbjct: 61  GGPTFQRLSGLARELDLWLEAGSIYESNPEDPARPFNTTFLICPDGTLAAKYAKLHPFDV 120

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES RV  G ++  + E +  KVGL  CYD+RF E+    AL+GA++  +PA
Sbjct: 121 VLPNGVTSRESDRVCPGKKL-TVAETDLGKVGLGICYDIRFGEMFRIMALEGAKLFAVPA 179

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASE 227
            +     K  HW  LL ARA++  CY++A  + G        G S ++DP+G  IA AS+
Sbjct: 180 NFTVNTGK-DHWEVLLRARAIENECYVIAPNQMGKKPRFTAYGNSLMVDPWGTVIARASD 238

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            P +I AE+  + V +VR     L+NRR    QL
Sbjct: 239 KPGVITAEIDLDYVTKVRQSTFTLDNRRPDVYQL 272


>UniRef50_A2FF61 Hydrolase NIT3, putative n=4 Tax=cellular organisms
           RepID=A2FF61_TRIVA
          Length = 273

 Score =  301 bits (773), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 114/272 (41%), Gaps = 15/272 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +   Q +       N    A  + + A++ A +  LPE              + ++  
Sbjct: 2   VKIGIVQLSSGDDKAANVARAAEKVKKCAQDGAEIVVLPEIFNGPYS--TAKFREYSEPE 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD---- 115
            GE   RL   +K N +  I          + +N        G  + ++ K+H++D    
Sbjct: 60  GGETWQRLSNMAKENNIILIGGSISEFCEDKIYNTSYIFDQQGKQIGKHRKMHMFDIDVK 119

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ES  +  GN+   +++    K+G+  C+D RFPELA   AL+GA+++++P A+ 
Sbjct: 120 GGQRFKESDALTPGNQ-VTVVDTSICKIGVCICFDFRFPELARLMALKGAKMIIVPGAFN 178

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  L   RA+D   + +      N      +   S ++ P+G  I  A    
Sbjct: 179 M-TTGPAHWELLFRQRAVDNQVFTIGCAPARNTEASYVSFANSIVVGPWGDVIYNAGIEE 237

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
              + E+  E+V  +R QLP+L+ RR    ++
Sbjct: 238 KAEVVEIDLEKVDSIRQQLPLLSARRTDVYEM 269


>UniRef50_D2UDH5 Putative carbon-nitrogen hydrolase family protein n=1
           Tax=Xanthomonas albilineans RepID=D2UDH5_XANAL
          Length = 348

 Score =  301 bits (772), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 64/279 (22%), Positives = 106/279 (37%), Gaps = 21/279 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDAD--LSVKSAQLL 60
           VA  Q         N     S +A+AA   A L  L E          +   +   A+ +
Sbjct: 62  VALIQERNHGDAAANLSAIESRVAEAAAQGARLVLLQELHNGAYFCQHESVEAFDLAEPI 121

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
            G    RL   +KR+ +  + ++      G   N  V  +  GN++ +Y K+H+ D    
Sbjct: 122 PGPSSQRLSALAKRHGVVLVGSLFERRAAGLYHNTAVVFEKDGNLLGKYRKMHIPDDPGF 181

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E      G+     ++    ++G++ C+D  +PE A   AL GAE+L+ P A    P  
Sbjct: 182 YEKFYFTPGDLGFTPIQTSVGRLGVLVCWDQWYPEAARLMALAGAELLLYPTAIGWDPDD 241

Query: 180 --------EHHWSTLLAARALDTTCYMVAAGECGNK----------NIGQSRIIDPFGVT 221
                      W       A+     +++    G++            G S ++ P G  
Sbjct: 242 AQAEQERQRDAWVLSHRGHAVANGIPVLSCNRVGHEPSPLGASGIQFWGNSHVLGPQGEF 301

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           IA A   P +++ EV  +R   VR   P L +RR     
Sbjct: 302 IAEAGTDPTVLVCEVDLQRSEHVRRIWPFLRDRRIDAYG 340


>UniRef50_B2SLI2 Beta-alanine synthetase n=122 Tax=Bacteria RepID=B2SLI2_XANOP
          Length = 299

 Score =  300 bits (770), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 63/279 (22%), Positives = 109/279 (39%), Gaps = 21/279 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVK--SAQLL 60
           VA  Q       E N  + AS +A+AA   A L  L E          +   +   A+ +
Sbjct: 13  VALIQERNHGDAEANLAVIASRVAEAAAQGAKLVLLQELHNGAYFCQHESVDEFDLAEPI 72

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
            G    RL   +K++ +  + ++      G   N  V  +  G ++ +Y K+H+ D    
Sbjct: 73  PGPSTERLGALAKQHGVVLVASLFERRAAGLYHNTAVVFEKDGRLLDKYRKMHIPDDPGF 132

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E      G+     ++    ++G++ C+D  +PE A   AL GAE+L+ P A    P  
Sbjct: 133 YEKFYFTPGDLGFTPIDTSVGRLGVLVCWDQWYPEAARLMALAGAELLLYPTAIGWDPDD 192

Query: 180 --------EHHWSTLLAARALDTTCYMVAAGECGNK----------NIGQSRIIDPFGVT 221
                      W       A+     +++    G++            G S ++ P G  
Sbjct: 193 QQPEQERQRDAWVLSHRGHAVANGVPVLSCNRVGHEPSPLGASGIQFWGNSHVLGPQGEF 252

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           IA A + P +++ +V  +R   VR   P L +RR     
Sbjct: 253 IAEAGQDPTVLICDVDLQRSEHVRRIWPFLRDRRIDAYG 291


>UniRef50_A1HQ26 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HQ26_9FIRM
          Length = 258

 Score =  300 bits (770), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 71/265 (26%), Positives = 108/265 (40%), Gaps = 14/265 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q  V      +N     +L  + A   A +  LPE              K A+ 
Sbjct: 1   MRIALVQMKVIAGAVAENRRRGLALAQEGAAR-ADVVVLPEIWTTGYALR--EVDKWAED 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFA 118
           +EG  +  +   S++     I         G+ +N  V +   GN+ A Y K+HL+    
Sbjct: 58  VEGLTISEMSNISRKYGAYIIAGSIPLRKNGKVYNGAVVIGPDGNVAAEYRKIHLFSMMG 117

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E R   AG+       ++G+  G+  CYDLRFPEL    AL GA+I+ LPA W     
Sbjct: 118 --EERFFAAGDRRCT-FNLKGVTAGIAICYDLRFPELFRVLALDGAQIVFLPAEWP--TA 172

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
           +  HW  L   RA++   ++      G        G S +I P G  +A   E   ++ A
Sbjct: 173 RGEHWHLLSRTRAIENQVFLCVVNCVGEHKGNPFYGHSMLIGPSGEVLAEGGEEETILYA 232

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
           E     V + R ++ V  +RR    
Sbjct: 233 EADFALVAKAREKMSVWQDRRPEVY 257


>UniRef50_UPI000051A529 PREDICTED: similar to Nitrilase and fragile histidine triad fusion
           protein CG7067-PA n=2 Tax=Coelomata RepID=UPI000051A529
          Length = 304

 Score =  299 bits (768), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 87/272 (31%), Positives = 126/272 (46%), Gaps = 17/272 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q   T+  EKN +    L  +A    AS+   PEA     D   D     AQ L G
Sbjct: 29  VAVCQMTSTNDKEKNLQTVRELSEKAKHRAASIAFFPEACDYLADSKKDTIA-MAQTLNG 87

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG---RAWNMLVALQA-GNIVARYAKLHLYD--- 115
             +   +  +K N +   L     +         N  + + + G IV+ Y K+HL+D   
Sbjct: 88  STVTSYKEIAKINKIWLSLGGIHEALDNNREHISNTHILINSEGEIVSTYRKIHLFDMDN 147

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                 + ES  V  G +I P +     K+ L  CYD+RFPEL+ +    GAEIL  P+A
Sbjct: 148 KNTGVRLMESDYVLPGQKIEPPISTPIGKLALSICYDMRFPELSFSLRNMGAEILTYPSA 207

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +        HW  LL ARA++T CY+VAA +    N      G + +IDP+G  IA  SE
Sbjct: 208 FTYQT-GAAHWEILLRARAIETQCYVVAAAQTSIHNKKRVSWGHAMVIDPWGSIIAQCSE 266

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
              +I+AE+    ++Q+R  +P  N+RR    
Sbjct: 267 KTDIILAEIDLNLLKQIRQNMPCENHRRTDLY 298


>UniRef50_Q0AX54 N-carbamoyl-D-amino acid amidohydrolase n=3 Tax=cellular organisms
           RepID=Q0AX54_SYNWW
          Length = 283

 Score =  299 bits (768), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 77/271 (28%), Positives = 128/271 (47%), Gaps = 16/271 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           ++  Q    +  ++N +    ++A AA   A +  LPE   +     A+L  + A+   G
Sbjct: 7   LSICQMKTGNDKDENLKKAGEMIAAAAGEGAEMVVLPEVFNSPY--QAELFPRYAEPFPG 64

Query: 63  EFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDA---- 116
                L   + ++ +  +        + G+ +N        G ++ R+ K HL+D     
Sbjct: 65  PSTDFLAAAACKHGLCIVGGSIIERDSQGKIYNSSFVFDERGELIGRHRKAHLFDIDIPG 124

Query: 117 -FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
             + +ES  ++AG  I  ++  +     LM CYD RFPELA A AL+GAE+LV+PAA+  
Sbjct: 125 RISFRESDTLNAGENI-TIVHYKSRLFALMICYDCRFPELARAAALEGAELLVIPAAFNT 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASEMPA 230
                 HW  L+  RA+D   ++VAA    N     +  G S ++DP+G  +  A     
Sbjct: 184 -TTGPAHWKLLMRCRAVDNQLFVVAASPARNPSASYQAWGHSLVVDPWGDILQEAGSGEE 242

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +I A +   R+ QVR +LP+L  RR    +L
Sbjct: 243 IIHARLDFSRLEQVRQELPLLRQRRKDLYRL 273


>UniRef50_C8WPR2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WPR2_EGGLE
          Length = 280

 Score =  299 bits (767), Expect = 6e-80,   Method: Composition-based stats.
 Identities = 65/270 (24%), Positives = 119/270 (44%), Gaps = 17/270 (6%)

Query: 3   VAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSAQL 59
           +A  QF         N +    ++A+AA   A L  LPE      + +       + A+ 
Sbjct: 15  LALVQFESVLCDPAANTQKACRMIAEAAAEGADLVVLPELFSTGYELNIVGPHVPELAEP 74

Query: 60  LEGEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF 117
           ++G  +  L+  ++      +  +       G  +N  V +   G ++  Y K HL+   
Sbjct: 75  VDGPTVRALQDAARAGNCYVVAGLALAYDMAGVPFNSSVVIDRQGELLGTYDKQHLWAL- 133

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E     +G +  P+ + +  ++G+M CYD+ FPE+A   ALQGA++++ P+AW +  
Sbjct: 134 ---ERFYFRSGCD-CPVFDTDFGRIGVMICYDMGFPEVARMLALQGADLILCPSAWCQE- 188

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAA-ASEMPALI 232
                W     ARAL+ T ++ A    G ++     G +++ +P G  +A  A E   ++
Sbjct: 189 -DMDVWDVNAPARALENTAFVAAVNRYGVEDQLVMPGHTKVCNPRGHVVAELAEEAEGVL 247

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
             E+    V   R + P L +RR     L+
Sbjct: 248 HVELDLNEVVDYRQRSPYLRDRRPDLYDLV 277


>UniRef50_O76463 Nitrilase homolog n=6 Tax=Bilateria RepID=NFT1_CAEEL
          Length = 440

 Score =  299 bits (766), Expect = 8e-80,   Method: Composition-based stats.
 Identities = 78/273 (28%), Positives = 128/273 (46%), Gaps = 16/273 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q    +  EKN +   +++ +A E    +  LPE       +  +     A   + 
Sbjct: 17  IAVCQMTSDNDLEKNFQAAKNMIERAGEKKCEMVFLPECFDFIGLNKNEQI-DLAMATDC 75

Query: 63  EFLGRLRRESKRNMMTT-ILTIHVPSTPG--RAWNMLVALQ-AGNIVARYAKLHLYDAF- 117
           E++ + R  ++++ +   +  +H          WN  + +   G   A Y KLHL+D   
Sbjct: 76  EYMEKYRELARKHNIWLSLGGLHHKDPSDAAHPWNTHLIIDSDGVTRAEYNKLHLFDLEI 135

Query: 118 ----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                + ES    AG E+ P ++    ++GL  CYD+RFPEL+L    +GA++L  P+A+
Sbjct: 136 PGKVRLMESEFSKAGTEMIPPVDTPIGRLGLSICYDVRFPELSLWNRKRGAQLLSFPSAF 195

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW TLL ARA++  CY+VAA + G  N      G S ++DP+G  +A  SE 
Sbjct: 196 TLNT-GLAHWETLLRARAIENQCYVVAAAQTGAHNPKRQSYGHSMVVDPWGAVVAQCSER 254

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             +  AE+    V  +R   PV ++RR     L
Sbjct: 255 VDMCFAEIDLSYVDTLREMQPVFSHRRSDLYTL 287


>UniRef50_B1I274 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Candidatus Desulforudis audaxviator MP104C
           RepID=B1I274_DESAP
          Length = 272

 Score =  299 bits (766), Expect = 9e-80,   Method: Composition-based stats.
 Identities = 71/263 (26%), Positives = 117/263 (44%), Gaps = 14/263 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL- 59
           + +   Q  VT+  E+N      + A+AA   A +  LPE       H  +   + A+  
Sbjct: 4   IKLGICQMPVTASKEQNLSRARQMAAEAARAGARVVVLPEMFNCPYQH--EFFTRFAETC 61

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLY---- 114
            +G+    L   ++   +  I      +  GR +N        G ++ R  KLHL+    
Sbjct: 62  PDGDTFRMLTSTARELGVYLIGGSIPEAEDGRTYNTCFVYGPDGRMLGRQRKLHLFNIET 121

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           D    +ES  +  G     +     +  G+  C+DLRFPEL    A +GAE++V PAA+ 
Sbjct: 122 DDLVFRESDTLSPGTGPPTVFVTPLVTFGVAICFDLRFPELFRDLAARGAELIVAPAAFN 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  LL ARA+D   ++  AG    +       G S +++P+   IA A E  
Sbjct: 182 T-FTGPPHWELLLRARAVDNQVFVAGAGPAWTEDSPYPYYGHSLVVNPWAEVIACAGERE 240

Query: 230 ALIMAEVTPERVRQVRAQLPVLN 252
            +++AE+   +V +VR +LP+  
Sbjct: 241 TVLLAEIDLGQVAEVRKKLPLHR 263


>UniRef50_B6K212 UPF0012 hydrolase n=1 Tax=Schizosaccharomyces japonicus yFS275
           RepID=B6K212_SCHJY
          Length = 334

 Score =  298 bits (765), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 64/274 (23%), Positives = 112/274 (40%), Gaps = 19/274 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +   Q         N +   + + +AA+N A++  LPE   +          + A+  
Sbjct: 49  FRLGLVQLLSGMDKMDNLKNARTKVLEAAKNGANIVVLPEIFNSPYS--VAHFREYAEDF 106

Query: 61  ----EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD 115
                      L + +K   +       V     + +N  +     G+++ ++ K+HL+D
Sbjct: 107 VTTSHSPSYDALSQMAKDAKVYLFGGSIVELDNDKVYNTALVFSPDGSLLGKHRKMHLFD 166

Query: 116 -----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
                     ES  +  GN +  + + E  K G+  CYD+RFPELA+  A  G   ++ P
Sbjct: 167 VDIPNGIRFIESEVLSPGNAMTMV-QTEFGKFGMGICYDIRFPELAMIAARNGCAGMIYP 225

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAA 225
           +A+        HW  L  +RA+D   ++       N        G S  +DP+G  +A A
Sbjct: 226 SAFNT-TTGPLHWELLARSRAVDNQIFVALCSPARNMDASYHAYGHSMAVDPYGKILAEA 284

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            E PA+I A++ P  +   R  +P+   RRF   
Sbjct: 285 QEGPAIIYADINPTTMEVCRRAIPLYTQRRFDMY 318


>UniRef50_B3E274 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=10 Tax=Desulfuromonadales RepID=B3E274_GEOLS
          Length = 262

 Score =  298 bits (764), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 83/264 (31%), Positives = 125/264 (47%), Gaps = 13/264 (4%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           +  AA QF V     + N     + + + AE   +L  LPE       +     V+ AQ 
Sbjct: 7   ITAAAIQFTVNQGDLDANLAYVRTALKRVAEQGVNLAVLPEMWSTGFAY--KNLVELAQR 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
            E   +  L   S +  +  + +   P+  GR +N +  +  G +VARY KLHL+     
Sbjct: 65  TE-AVVAELCELSAQYKLVIVGSQPEPADDGRVFNTIHVVDNGQMVARYRKLHLFSLLG- 122

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E R    G+    L E    KVG++ CYDLRFPEL+   AL+GA ++ +PA W +   +
Sbjct: 123 -EDRAFKGGDSWC-LAETSIGKVGVIICYDLRFPELSRRLALEGARVICVPAQWPKP--R 178

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMAE 235
           + HW TLL ARA++   Y+V+   CG        G S +IDP G  +A A E    + A 
Sbjct: 179 QEHWRTLLRARAIENQLYIVSCNACGQIGKLDFFGMSMVIDPKGEVLADAGEAACEVTAT 238

Query: 236 VTPERVRQVRAQLPVLNNRRFAPP 259
           +  + +   RAQ+P   +RR    
Sbjct: 239 LDWQVMEAWRAQIPCFGDRRPELY 262


>UniRef50_A8MG18 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Bacteria RepID=A8MG18_ALKOO
          Length = 261

 Score =  297 bits (762), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 68/266 (25%), Positives = 108/266 (40%), Gaps = 12/266 (4%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M ++  Q  +T    E N +    L+  AA+ +    ALPE          +   +    
Sbjct: 1   MKISLIQMKMTFEDMEHNFKKAEELIRLAAKENPDTIALPETWSTGFFP-KENIKEFCDQ 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
                     + SK   +  I    +       +N        G  +A Y K HL+    
Sbjct: 60  NGNRTKRLFSKLSKELNVNIIAGSVINEKQDGIYNTSYIFNKQGECIAEYDKTHLFSYMG 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E +  + G+    + E++G+K G++ CYD+RF EL    ALQ  +IL + A W    L
Sbjct: 120 --EDQYFEKGS-GITVFELDGIKCGIVICYDIRFVELVRTLALQEIKILFVVAQWPM--L 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMA 234
           + HHW  L  ARA++   ++     CG        G S +IDP+G  I  AS    +I  
Sbjct: 175 RIHHWQILNEARAIENQIFVACVNSCGRAGETIYGGNSALIDPWGEVILRASNQEEIITG 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
            +    V ++R  + V  +RR    Q
Sbjct: 235 NLDLSIVEKIRDTIHVYKDRRPDLYQ 260


>UniRef50_D2R0U8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R0U8_9PLAN
          Length = 292

 Score =  297 bits (761), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 94/268 (35%), Positives = 138/268 (51%), Gaps = 18/268 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q   T     N     +L+ QAA   A L  LPE  ++    D   +   AQ L G
Sbjct: 9   VAAIQMRATDDVAANFATAVTLVGQAAAAGARLVVLPELFVSYG--DLARTAAVAQSLLG 66

Query: 63  EFLGRLRRESKRNMMTTILTIHVP--STPGRAWNMLVALQA-GNIVARYAKLHLYDAF-- 117
            ++  L++ +K   +  +        +   RA+N    +   G IVA Y K+HL+D    
Sbjct: 67  TWITELQQLAKSKNIWLVAGSIPEQVANDQRAYNCSTVISPTGEIVAAYRKIHLFDVEIA 126

Query: 118 ---AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              A QES  +  GNE+  +++++  +VG+  CYDLRFPEL    A  GAE++V+PAA+ 
Sbjct: 127 GRVASQESLHLLPGNELV-VVKIDDWQVGIAICYDLRFPELFRNLATLGAELVVIPAAFT 185

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS-EM 228
           R    + HW  L+  RALD   Y+VAA + G+ N      G S I++P+G  IA    E 
Sbjct: 186 R-TTGKDHWDLLVRTRALDAQAYIVAANQGGDHNGQSSSYGHSMIVEPWGKVIAQIDSED 244

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
             ++ + +  +RV +VR QLPVL NRR 
Sbjct: 245 EGIVFSSIDRKRVAEVRRQLPVLRNRRL 272


>UniRef50_Q7MHE3 Predicted amidohydrolase n=69 Tax=Proteobacteria RepID=Q7MHE3_VIBVY
          Length = 300

 Score =  296 bits (759), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 73/268 (27%), Positives = 120/268 (44%), Gaps = 17/268 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL- 60
            +A  Q   TS    N         QAA   ASL   PE  L       +   + A+ L 
Sbjct: 29  RIAIIQMTSTSDCTDNVAYIEHWAEQAALQGASLVVTPENALLFG--GREDYHQHAEPLG 86

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA--- 116
            G     + + +KR  +T ++               +     G  +  Y+KLH++D    
Sbjct: 87  NGPLQQAMAQLAKRLAVTLVIGSMPIRQGHDVTTTSLVFGPNGERLGHYSKLHMFDVEVS 146

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES    AG+  + ++     ++GL  CYD+RFP L      +GA+IL++PAA+
Sbjct: 147 DGHGHYRESDSFLAGDR-SSVVATPIGRLGLSICYDVRFPALYQTLRQKGADILLVPAAF 205

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASEM 228
                 E HW  LL ARA++  C+++AA + G      +  G S +IDP+G  +A   + 
Sbjct: 206 TA-VTGEAHWEVLLRARAIENQCWVIAAAQGGMHSASRETWGHSMVIDPWGKVVAQLPQQ 264

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
             L++AE+       +R ++PV+ + RF
Sbjct: 265 GDLLLAEIDLALSDTIRRKMPVVKHSRF 292


>UniRef50_D1Y612 Hydrolase n=2 Tax=Bacteria RepID=D1Y612_9BACT
          Length = 274

 Score =  296 bits (759), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 81/272 (29%), Positives = 122/272 (44%), Gaps = 19/272 (6%)

Query: 4   AAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGE 63
           A  Q       + N +     + +AA   A   + PE          +       + EG 
Sbjct: 7   AVIQMDTRDNKDANLKAACDFIDEAASKGAKFVSFPEVFNVI----DEGQEAPELVPEGR 62

Query: 64  FLGRLRRESKRNMMTTILTIHVP---STPGRAWNMLVALQAGNIVARYAKLH-----LYD 115
            +  +  +++R+ +                +     V    G +VA+Y KLH     L D
Sbjct: 63  TISLMAEKARRHNLWIHCGSIAEVNPEGDRKFNTTAVLNPQGRMVAKYRKLHTFDITLPD 122

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +ES R+  G E+    + E   +GL  CYD+RFPEL    AL GA+IL  PA +  
Sbjct: 123 GSVAEESARIKPGREMVT-ADTEMGCLGLSICYDIRFPELYRYLALHGAQILFAPANFRM 181

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTIAAASEMPA 230
              K  HW  +L ARA++ TCY+VAAG+ G     + + G S IIDP+G  +A ASE   
Sbjct: 182 ATGK-DHWEAILRARAIENTCYVVAAGQYGKKHGTSDSFGNSMIIDPWGTVVARASEGAG 240

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           L + E+  + + +VR+ LP L NRR      +
Sbjct: 241 LAVGEIDLDYLDKVRSHLPSLKNRRADVYDTV 272


>UniRef50_A6DKQ0 Carbon-nitrogen hydrolase family protein n=1 Tax=Lentisphaera
           araneosa HTCC2155 RepID=A6DKQ0_9BACT
          Length = 286

 Score =  296 bits (759), Expect = 6e-79,   Method: Composition-based stats.
 Identities = 70/275 (25%), Positives = 117/275 (42%), Gaps = 16/275 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQL 59
            +A  Q       E N +    L+A AA++ A++    E  L+            + AQ 
Sbjct: 3   KLALLQSRDYGSPEANKKQHLKLIADAAKSGANIICTQELFLSNYFCREQNTEHFQYAQK 62

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
           ++ E L   ++ +K + +   L+    +  G  +N  V +   G  + +Y KLH+     
Sbjct: 63  IDQELLADFQQCAKNHGVVLALSFFEEALNGVYYNTSVIIDADGTYLGKYRKLHIPQDPY 122

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR-GP 177
            +E      GN   P+ E +  K+ L+ C+D  FPE A    L GAEI+++P A      
Sbjct: 123 FEEKFYFTPGNLGVPVFETQFGKISLIICWDQWFPETARLACLAGAEIILVPTAIGWLPD 182

Query: 178 LKEHH-------WSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAA- 225
            KE H       W+ +    A+   CY  A    G +      GQS I D +G T+A A 
Sbjct: 183 EKEEHGAQQAHSWTQVQLGHAVANGCYYAAVNRVGIEEPIQFWGQSFISDFYGQTLAQAS 242

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           S    ++ A++  +++R+ R   P   +RR     
Sbjct: 243 SNEEEILFADLDLKQLREHRQIWPFFRDRRIDAYD 277


>UniRef50_D1Y5M0 Hydrolase C26A3.11 n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y5M0_9BACT
          Length = 283

 Score =  296 bits (758), Expect = 6e-79,   Method: Composition-based stats.
 Identities = 56/272 (20%), Positives = 111/272 (40%), Gaps = 16/272 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q  V +  + N +   + +AQ+ +  A +  LPE                A+  
Sbjct: 11  MKIALIQLRVDNSKQNNLDRACAFIAQSKQGGADMAILPEMFSCPY--QTKNFPLYAEKA 68

Query: 61  EGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
            G+   +    +++N +  +   +      G+ +N        G  +A + K H++D   
Sbjct: 69  GGKAWLQFSETARKNNIYLVAGSMPEVDEEGKVYNTSFVFDREGAQLASHRKAHMFDIDV 128

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES  +  G++     E E   +GL+ CYD RFPE++   A +GA+++ +PAA+
Sbjct: 129 PGGQRFRESDTLTPGDK-VTTFETEFGLMGLLVCYDFRFPEMSRIMANRGAKVIFVPAAF 187

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW  L   RA D   + V      ++         S ++ P+G      +  
Sbjct: 188 NM-TTGPAHWDLLFRCRAQDFQVFTVGCAPARDEGGCYVSYANSMVVGPWGDVKLRMATE 246

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            ++   ++    +++VR   P+ N+ R    +
Sbjct: 247 ESMEFCDIDLNELKKVRTSFPLWNHYRKGLYE 278


>UniRef50_O76464 Nitrilase homolog n=6 Tax=Sophophora RepID=NFT1_DROME
          Length = 460

 Score =  294 bits (754), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 78/271 (28%), Positives = 122/271 (45%), Gaps = 13/271 (4%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            +A GQ   TS    N      L+ +A   +A +  LPE            +++ ++ L+
Sbjct: 34  TIAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVG-ESRTQTIELSEGLD 92

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA-- 118
           GE + + R  +K N +   L         + +N  V L   G + A Y KLH++D     
Sbjct: 93  GELMAQYRELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTTKE 152

Query: 119 --IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
             ++ES  V  G  +   +     ++GL  CYDLRF E A+     GA +L  P+A+   
Sbjct: 153 VRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYA 212

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMP-A 230
             K  HW  LL ARA++T C++VAA + G  N      G S I+ P+G  +A  SE    
Sbjct: 213 TGK-AHWEILLRARAIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELD 271

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +  AEV    ++ +   +P   +RR     L
Sbjct: 272 IGTAEVDLSVLQSLYQTMPCFEHRRNDIYAL 302


>UniRef50_D1VY57 Hydrolase, carbon-nitrogen family n=1 Tax=Prevotella timonensis
           CRIS 5C-B1 RepID=D1VY57_9BACT
          Length = 318

 Score =  294 bits (754), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 55/283 (19%), Positives = 106/283 (37%), Gaps = 23/283 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLS--VKSAQ 58
           + +   Q   T   + N +  A  +   A+  A L  L E   +      +       A+
Sbjct: 27  IRIGILQLRNTECVDDNKKKIAENITDLAQRGAQLIVLQELHNSLYFCQVEDVNNFDLAE 86

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
            + G       + +++  +  + ++     PG   N  V ++  G I  +Y K+H+ D  
Sbjct: 87  PIPGPSTEYYGKLAQQLGIVIVTSLFEKRAPGLYHNTAVVIEKDGTIAGKYRKMHIPDDP 146

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
           A  E      G+     ++    ++G++ C+D  +PE A   ALQGA++L+ P A     
Sbjct: 147 AYYEKFYFTPGDLGFHPIDTSVGRLGVLVCWDQWYPEAARLMALQGAQLLIYPTAIGYES 206

Query: 178 LKEH--------HWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRIIDPF 218
             +          W+T+    A+     ++     G++             G S +  P 
Sbjct: 207 SDDEDEQQRQRNAWTTVQRGHAVANGLPVITVNRVGHEDDPSGQTNGIDFWGSSFVAGPQ 266

Query: 219 GVTIAAA-SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           G     A  +    ++ ++  +   QVR   P L +RR    Q
Sbjct: 267 GELYYQACDDDEESVVIDIDLDHSEQVRCWWPFLRDRRIENYQ 309


>UniRef50_C4XZI3 Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC
           42720 RepID=C4XZI3_CLAL4
          Length = 344

 Score =  294 bits (753), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 71/280 (25%), Positives = 116/280 (41%), Gaps = 24/280 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAEN----DASLFALPEALLARDDHDADLSVKS 56
           + VA  Q    +    N     S + +A          +  LPE   +      D   + 
Sbjct: 58  LKVALIQLKAGADKAANLSKVQSYIDKAVSESTIGKPDVVMLPECFNSPYA--VDKFREY 115

Query: 57  AQLLEG-EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLY 114
           A+++ G E    L + +KR+ +  +      S   + +N  +     G+I+A++ K HL+
Sbjct: 116 AEVIPGGETTKFLAQLAKRHGVFIVGGSFPESDQDKIYNTSLTFSPSGDIIAKHRKAHLF 175

Query: 115 D-----AFAIQESRRVDAGNEIAPLLEV-EGMKVGLMTCYDLRFPELALAQALQ--GAEI 166
           D         +ES  + AG++   +  + +   VGL  CYD+RFPELA+A +     A  
Sbjct: 176 DIDIPNGITFKESITLSAGDKA-TVFGLGDFGTVGLGICYDIRFPELAMAASRAPHNAFA 234

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC------GNKNIGQSRIIDPFGV 220
           +  P A+        HW  L  ARA+D   + V           G +  G S ++DP G 
Sbjct: 235 MFYPGAFNT-TTGPLHWHLLARARAVDNEVFTVLCSPARDVGGSGYQAYGHSLVVDPSGK 293

Query: 221 TIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            IA A E   ++ AE+    +   R  +PV   RRF    
Sbjct: 294 IIAEAGEGEEILYAELDHSLLPSARTGIPVHYQRRFDIYD 333


>UniRef50_A0L7H1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L7H1_MAGSM
          Length = 275

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 74/267 (27%), Positives = 120/267 (44%), Gaps = 15/267 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +L A  Q    +    N      L+ +AA   A L  LPE        + +         
Sbjct: 7   VLAAVIQTNSGNDRVHNLMRAEQLLEEAATAGAKLLVLPENFSFFGADEKEKLAHQEDPQ 66

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYD-- 115
            G  L  ++  ++R+    +            R  N    +   G +VARY K+HL+D  
Sbjct: 67  HGPSLRMVQAFAQRHGAWVVAGSIPTDVGESQRVANSSFVVNDQGQVVARYDKIHLFDVT 126

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES  + AG++   +++    ++GL  CYDLRFPEL  A    GAEI  +PAA
Sbjct: 127 LNGGEGYRESDMIRAGSQPV-VVDSPFGRIGLSICYDLRFPELYRALTDAGAEIFTVPAA 185

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++  C+++A  + G         G S I++P+G  +A  ++
Sbjct: 186 FTL-TTGQVHWELLLRARAVENFCHLLAPNQWGRHPGNRKTYGSSMIVEPWGSVVARVAD 244

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNR 254
                +A + P RV + R+Q+P L +R
Sbjct: 245 GEGYALAPLDPARVARCRSQIPCLQHR 271


>UniRef50_B0SIF2 Amidohydrolase n=3 Tax=Bacteria RepID=B0SIF2_LEPBA
          Length = 269

 Score =  293 bits (751), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 77/270 (28%), Positives = 122/270 (45%), Gaps = 17/270 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              A  Q   T+    N   C   + +AA   A +  LPE            S+     +
Sbjct: 3   FKAAVVQVTSTARVSNNLTKCRQFVEEAARAGAKVIGLPENFSFMGSESEKQSLLG--QI 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHV-PSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
           E E +  L+  +    +  +       +  G+ +N  V +   G  V RY K+HL+D   
Sbjct: 61  EDETILFLKETASELGIYLLGGGFPTKAPSGKVFNTAVMINPKGEEVFRYHKVHLFDAVV 120

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
              F  +ES   ++G ++  +++ E  K+    CYDLRFPEL  A + QG ++  LPAA+
Sbjct: 121 GDGFPYKESNHTESGEKVPEVIQTEYGKISSAICYDLRFPELFRALSKQGVDLCFLPAAF 180

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-------NIGQSRIIDPFGVTIAAAS 226
              P  E HW  LL ARA++   Y++A G+ G           G S II P+G  +A   
Sbjct: 181 TV-PTGEAHWHVLLRARAIENLMYVLAPGQTGTHDPHGKRKTFGHSLIISPWGEILAELD 239

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
                 +A +  E++ ++R  LP LN+R+F
Sbjct: 240 HEEGFAIATMEMEKLSEIRNTLPSLNHRKF 269


>UniRef50_Q2BKP4 Putative carbon-nitrogen hydrolase n=1 Tax=Neptuniibacter
           caesariensis RepID=Q2BKP4_9GAMM
          Length = 276

 Score =  291 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 74/274 (27%), Positives = 121/274 (44%), Gaps = 26/274 (9%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSA-QLL 60
            VAA Q         N      L+ QA  ++A L  LPE        D+   ++ A +  
Sbjct: 3   RVAAVQMCSGQDLNANLAQLDGLIEQAVASNAELLLLPENFA---LLDSQALIELAFEES 59

Query: 61  EGEFL-GRLRRESKRNMMTTILTIHV------PSTPGRAWNMLVALQA-GNIVARYAKLH 112
               +  RL++ +    +  I            +   + ++  + +   G + A Y K+H
Sbjct: 60  RSPSVLNRLKQIAHEKGIWLIAGSFPWLCDSPQNGKTKVFSRSLLIDPQGELKAHYDKVH 119

Query: 113 LYDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI 166
           L+D        A +ES     G E+  + +      GL  CYDLRFPE     A  GA I
Sbjct: 120 LFDVDVEDKHAAYRESDYFTPGKELV-VEQTSVGCFGLSICYDLRFPEHYQRLADMGANI 178

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVT 221
           +++P+A+      + HW  LL ARA++T  Y++AA + G         G S I+DP+G  
Sbjct: 179 MLVPSAFTA-VTGKAHWEVLLRARAIETQSYVIAANQAGKHTASRSSWGHSMIVDPWGKV 237

Query: 222 IAAA-SEMPALIMAEVTPERVRQVRAQLPVLNNR 254
           +A   ++ P L +A++  + VR  R  +PV  +R
Sbjct: 238 LAECHNDGPGLAVADIDLQEVRNRRKAMPVTLHR 271


>UniRef50_B0MEV6 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0MEV6_9FIRM
          Length = 272

 Score =  291 bits (746), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 82/268 (30%), Positives = 123/268 (45%), Gaps = 7/268 (2%)

Query: 1   ML--VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M    A  Q   +   EKN         +A E  A     PE  +     +     + AQ
Sbjct: 1   MKSIAAIAQCRASQEPEKNLCKAEFFCREAREESACFVIFPEYFMTYYPIEGSAYYEKAQ 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHV---PSTPGRAWNMLVALQA-GNIVARYAKLHLY 114
            L+G F+  ++R +  +    +  +       + G+ +N  V L   GN+ + Y K HL+
Sbjct: 61  TLDGPFVQGMKRLAAAHGQWILFGMSEKPGRDSGGKCFNTAVLLDDRGNLCSVYRKTHLF 120

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           DAF+ +ES     G  +   +     K GL TCYDLRFPE A  QAL+GAE+L+ P+AWV
Sbjct: 121 DAFSWKESDSTLPGEVLHEPVNTPLGKAGLGTCYDLRFPEPARIQALKGAEVLIYPSAWV 180

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECG-NKNIGQSRIIDPFGVTIAAASEMPALIM 233
            GP K   W  LL ARA++ T + +          +G+S   DP G  +A       LI+
Sbjct: 181 DGPDKFMQWEALLRARAIENTVFTIGCCHYSEEHYMGRSLAFDPSGRKLAEGEAGEELIV 240

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             V  ++   +  Q+PV+ NRR     +
Sbjct: 241 LPVDTDQRDAIIHQVPVMKNRRTDLYDI 268


>UniRef50_O31664 UPF0012 hydrolase mtnU n=96 Tax=Bacilli RepID=MTNU_BACSU
          Length = 259

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 63/264 (23%), Positives = 112/264 (42%), Gaps = 14/264 (5%)

Query: 2   LVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            ++  QF ++     +N +     + +     A +  LPE        D     + A   
Sbjct: 4   TISCLQFDISYGKPSENIKKAEFFIEK-ESKHADVLVLPELWTTGY--DLANLDELADED 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAI 119
                  L++ +K++ +  +            +N +      G I+  Y K HL+    +
Sbjct: 61  GRSAQSWLKKTAKKHGVHIVAGSVAVRKNSDVYNTMYIADKEGQIIKEYRKAHLFQL--M 118

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E   + AG+E     E++G+K   + CYD+RFPE       +GA +L + A W     +
Sbjct: 119 DEHLYLSAGSEDG-YFELDGVKSSGLICYDIRFPEWIRKHTTKGANVLFISAEWPLP--R 175

Query: 180 EHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAE 235
             HW +LL ARA++  C++ A    G    N+  G S IIDP+G  +A       ++ AE
Sbjct: 176 LDHWKSLLIARAIENQCFVAACNCTGSNPDNEFAGHSLIIDPWGRVLAEGGREEGIVRAE 235

Query: 236 VTPERVRQVRAQLPVLNNRRFAPP 259
           +  +   +VR  +PV ++ R    
Sbjct: 236 IDLQESAEVRESIPVFDDIRKDLY 259


>UniRef50_A7GE66 Hydrolase, carbon-nitrogen family n=24 Tax=cellular organisms
           RepID=A7GE66_CLOBL
          Length = 278

 Score =  290 bits (744), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 69/274 (25%), Positives = 126/274 (45%), Gaps = 15/274 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSA--Q 58
           + +A  Q  V    +KN +    ++ +A + + ++  LPE      ++           +
Sbjct: 4   LKIALCQMQVQKEKKKNIKKAIEMLTKAKKENCNIAVLPEMFNCPYENKCFKPYGEIINE 63

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-- 115
              GE +  +++ +K   +  +          + +N  +     G ++A++ K+HL+D  
Sbjct: 64  ENGGETVKAIKKAAKDLELYIVAGSIPEIEGDKIYNTSMVFDNKGVLIAKHRKVHLFDID 123

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES  + AGN+I  L      K+G+M CYD+RFPEL+   A++GA+I+  PAA
Sbjct: 124 VKGGVTFKESDTLTAGNKI-TLFNTPWGKLGVMICYDIRFPELSRIMAVKGAKIIFTPAA 182

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +        HW TL  +RALD   YMV      ++N      G S I  P+G  +A    
Sbjct: 183 FNM-TTGPAHWDTLFKSRALDNQVYMVGVAPARDENSNYVSYGNSLIASPWGNILAKLDA 241

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
              ++ +E+  +   ++R +LP+L + R     L
Sbjct: 242 KEDILFSEIDLDYESKIREELPLLKHIRKDIYSL 275


>UniRef50_B0TEY4 Hydrolase, carbon-nitrogen family n=1 Tax=Heliobacterium
           modesticaldum Ice1 RepID=B0TEY4_HELMI
          Length = 265

 Score =  290 bits (743), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 82/269 (30%), Positives = 113/269 (42%), Gaps = 17/269 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M V   QF V +   + N E  A  MA+A E    +  LPE          D    +A  
Sbjct: 1   MKVGLLQFNVCSGDRKANVETVARYMAEAREACPDVLVLPEMWTTGY----DWVNLAALA 56

Query: 60  LEGEFLGRLRR-ESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF 117
            +GE  G L    +K    T +         GR  N L A    G  +  Y K+HL+   
Sbjct: 57  DDGESFGALLACWAKETGATIVGGSSPVGANGRYANTLYAYTPEGERILSYEKVHLFGMM 116

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E R + AG+       +  +  G + CYDLRFPE      L G EIL +PA W    
Sbjct: 117 G--EERHLAAGSSTGNFC-IGAVPCGAVICYDLRFPEWIRKTVLAGCEILFIPAQWPLS- 172

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPALI 232
            +  HW  LL ARA++  CY++A    G         G S +IDP+GV    A E    I
Sbjct: 173 -RLDHWRILLQARAIENQCYVIACNRTGRDEQGVAFAGHSMVIDPWGVIAVEAGEEEGWI 231

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             E+  ++V +VR ++ V  +RR      
Sbjct: 232 WGEIDRDKVERVRRKMTVFADRRLDLYDF 260


>UniRef50_Q0HEI5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=21 Tax=Shewanella RepID=Q0HEI5_SHESM
          Length = 282

 Score =  290 bits (743), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 75/282 (26%), Positives = 121/282 (42%), Gaps = 23/282 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAEND-------ASLFALPEALLARDDHDADLS 53
           M ++  Q   +     N     S + +              L  LPE  L    H++   
Sbjct: 1   MRISLLQCQSSRDVSANLLFIESQLEELTRQRLQWDKDAPHLVVLPECSLLFGGHESQQL 60

Query: 54  VKSAQLLEGEFLGRLRRESKRNMMTTILTIHV-PSTPGRAWNMLVALQA-GNIVARYAKL 111
             +           L   + R  +  +       +  GR ++        G+ + +Y KL
Sbjct: 61  AYAGDSHLSPLKSALSALAARYCVYMVAGTIPALAEDGRVYSRCYLFDDKGDTLGQYDKL 120

Query: 112 HLYDAFA------IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
           HL+D          +ES     GN I  +++    K+GL  CYDLRFP+L  A  L GAE
Sbjct: 121 HLFDVDVADGTKQYRESETFCPGNHI-SVIDTPFGKIGLTICYDLRFPDLFRALRLAGAE 179

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG------NKNIGQSRIIDPFG 219
           I+ +P+A+ +    E HW  LL ARA++T C+++AA + G       +  GQS +I P+G
Sbjct: 180 IITVPSAFTK-VTGEAHWQVLLQARAIETQCFILAAAQWGAHNEGSRETWGQSMVIGPWG 238

Query: 220 VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             IA        + A++    V  +R+++PV  + RF  P L
Sbjct: 239 EVIAEQKTGTGWVHADIDVAEVHSIRSKMPVAQHNRFTAPNL 280


>UniRef50_Q702A9 Putative predicted amidohydrolase n=6 Tax=Archaea
           RepID=Q702A9_9CREN
          Length = 285

 Score =  289 bits (741), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 75/267 (28%), Positives = 130/267 (48%), Gaps = 7/267 (2%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQ 58
              A  Q   +   E N      L+ +AA+  A L   PE     +  +   +   + A+
Sbjct: 8   FRAAIVQMKSSEEKEHNLAYSVKLINEAAKRKARLICFPEFQMAYSPAEQKTESLHRIAE 67

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVP----STPGRAWNMLVALQA-GNIVARYAKLHL 113
            + G F+  L   +++N +  I T++          + ++  + +   G + + Y K+HL
Sbjct: 68  KICGNFVSTLSNSARQNKINVIATMYEIINANEKSQKVFDTGIIINELGKVQSIYRKVHL 127

Query: 114 YDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
           YDA   +ES+++ AG+ I    +     +GL+ CYD+RFPE++    + GA ILV P+AW
Sbjct: 128 YDALGFKESKKLLAGSIIEKPSKTSVGNLGLLICYDMRFPEISRILTVNGANILVSPSAW 187

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIM 233
           V G +K+ HW  ++ ARA++   Y++A  + GN   G S  IDPFG T+        +  
Sbjct: 188 VAGFMKKVHWEVMVRARAIENGVYVLAPNQVGNIYCGHSMAIDPFGATVLDMKNRQGIEY 247

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            ++   ++   R  LP+L NRR    +
Sbjct: 248 VDIDTAKIDTTRRTLPLLMNRRTDVYR 274


>UniRef50_Q9KE11 BH1047 protein n=2 Tax=Bacillaceae RepID=Q9KE11_BACHD
          Length = 271

 Score =  289 bits (740), Expect = 8e-77,   Method: Composition-based stats.
 Identities = 68/269 (25%), Positives = 117/269 (43%), Gaps = 15/269 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAEND--ASLFALPEALLARDDHDADLSVKSA 57
           M VA  Q  +       N       +    + +    L  LPE          D     A
Sbjct: 1   MKVALYQMDILPGDPRGNERKVKEWIEDVMQQEDVPDLLVLPEMWTTAYTL--DQLEHLA 58

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA 116
           +  E      L+  ++ + +  +         G+ +N  +     G+ V +Y K+HL   
Sbjct: 59  EGEERYTELFLKELAREHNVNIVAGSIAKKEKGKLYNRALVFDRRGHTVYQYDKIHL--V 116

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
             + E   +  G+  A + E+EG K+GL+ CYDLRFPEL  + AL+GAEI+ + A W   
Sbjct: 117 PMLSEPDYLTGGDAAASVFELEGTKMGLVICYDLRFPELMRSLALEGAEIVFIVAEWPEA 176

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAAS-EMPAL 231
             +  HW  L  ARA++   Y+++    G        G+S +IDP+G  +   S +    
Sbjct: 177 --RAVHWEVLQRARAIENQSYVISCNRVGAYAGVTFAGRSMVIDPWGDVLIQGSRDQEQT 234

Query: 232 IMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           +  ++ P++V +VR  +P+  +R     +
Sbjct: 235 LTTKLNPDKVSEVREAVPIFQSRVPTKYK 263


>UniRef50_A5VIE2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=10 Tax=Lactobacillales RepID=A5VIE2_LACRD
          Length = 261

 Score =  288 bits (738), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 64/265 (24%), Positives = 108/265 (40%), Gaps = 13/265 (4%)

Query: 2   LVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            VA  Q  +      +N +     + +AA + A +  LPE          D   + A   
Sbjct: 4   KVALAQLDIQLGNPAENYQKAKQAIEEAANHHADIVVLPEMWNIGYAL--DQLAELADEN 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
             +        + +N +  +            +N        GN+++ Y K+HL+    +
Sbjct: 62  GQKTQQFFSELALKNQINIVGGSVAVRNGQSFFNTTYVYDQNGNLISSYEKVHLF--GLM 119

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E + ++AG +     ++ G+      CYDLRFPE     A  G +IL  PA W     +
Sbjct: 120 NEDQYLEAGQK-ENHFKLAGIPSASFICYDLRFPEWIRTVARYGTDILYFPAEWPSK--R 176

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAE 235
              W  +L +RA++   ++VA    G        G S +IDP G  I  A E+  +  AE
Sbjct: 177 IEQWKIMLRSRAIENQAFVVAVNRVGTDLENSFNGHSLVIDPLGQVIHDAGEVEQVSYAE 236

Query: 236 VTPERVRQVRAQLPVLNNRRFAPPQ 260
           +   ++ QVR  +PV  +RR +   
Sbjct: 237 IDLAQLAQVRGPIPVFKDRRPSLYH 261


>UniRef50_Q972L1 281aa long hypothetical beta-ureidopropionase n=1 Tax=Sulfolobus
           tokodaii RepID=Q972L1_SULTO
          Length = 281

 Score =  288 bits (738), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 58/270 (21%), Positives = 101/270 (37%), Gaps = 15/270 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADL--SVKSAQ 58
           + +A  Q       E N +        A ++ A L    E    +     +       A+
Sbjct: 5   VKIAMIQMGSVESKEANIQKALEYTKAAVKDGAELIVYNELFTTQYFPATEDPKFFDLAE 64

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQAGNIVARYAKLHLYDA 116
             +G  +      SK+  +  I+TI        G  ++  + ++ G ++ +Y K H+   
Sbjct: 65  PEDGPTVRVFAEFSKQYKIGMIITIFEEDKKIKGIYYDTAIFIKDGKVLGKYRKTHIPQV 124

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
               E      G E  P+ +  G K+G + CYD  FPE      L+GA+I+ +P      
Sbjct: 125 PGYYEKFYFKPGKE-YPVFDFGGYKIGAVICYDRHFPEGVRILTLKGADIVTIP---TTT 180

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGEC-----GNK--NIGQSRIIDPFGVTIAAASEMP 229
                 W   L A A   T Y+V          G +    G+S + DP G  +   S   
Sbjct: 181 NFYPETWELELRAHAAFNTIYVVGVNRTPEIFQGKEIDYFGKSLVADPTGNILKEMSSQE 240

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
              + +V  + +R+ R + P L +R+    
Sbjct: 241 GYEIVDVNLDFIRERRKKAPFLRDRKPENY 270


>UniRef50_Q557J5 Nitrilase homolog 1 n=1 Tax=Dictyostelium discoideum
           RepID=NIT1_DICDI
          Length = 291

 Score =  288 bits (738), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 77/280 (27%), Positives = 133/280 (47%), Gaps = 22/280 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLAR-DDHDADLSVKSAQLL 60
            +  GQ   T+  E N   C  ++ +A EN  +LF LPE             S  +A+ L
Sbjct: 14  RIGLGQITSTNNKEDNFRKCKEMIEKAVENKVNLFCLPECFAFISGGIHQFESRDNAEYL 73

Query: 61  E--GEFLGRLRRESKRNMMTT-ILTIHVP---STPGRAWNMLVALQ-AGNIVARYAKLHL 113
           +  G  + R +  +K+N +   +   H           +N  + +   G IV  Y K+HL
Sbjct: 74  DQKGGIIERYKDLAKQNNIWLSLGGFHEKILDDPNDMIYNTHLIIDSNGVIVCEYRKMHL 133

Query: 114 YD------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +D         + ES+ V  GN++  + +    K+GL  CYDLRFPEL L+     A+IL
Sbjct: 134 FDVDIPSKGVKMNESKVVKGGNDLV-VCDSPVGKLGLSICYDLRFPELYLSLRRMDAQIL 192

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTI 222
           ++P+A+++    E HW  LL ARA++   Y++AA + G+ +      G S IIDP+G  +
Sbjct: 193 LVPSAFMKST-GEAHWKPLLQARAIENQTYVIAAAQTGDHHSKRSSYGHSMIIDPWGKVL 251

Query: 223 AAASEM-PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
               +    +   ++  + +   R  +PV N+++    ++
Sbjct: 252 HDLPDNLNDIAFVDIDLDYISTCRENIPVFNHKKLNNYKI 291


>UniRef50_P58054 UPF0012 hydrolase ybeM n=121 Tax=Proteobacteria RepID=YBEM_ECO57
          Length = 262

 Score =  288 bits (738), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 260/262 (99%), Positives = 260/262 (99%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           MLVAAGQFAVTSVWEKNAEICASLMAQAAEND SLF LPEALLARDDHDADLSVKSAQLL
Sbjct: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLL 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ
Sbjct: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE
Sbjct: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
           HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
Sbjct: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240

Query: 241 VRQVRAQLPVLNNRRFAPPQLL 262
           VRQVRAQLPVLNNRRFAPPQLL
Sbjct: 241 VRQVRAQLPVLNNRRFAPPQLL 262


>UniRef50_B2SXB2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=15 Tax=Proteobacteria RepID=B2SXB2_BURPP
          Length = 283

 Score =  287 bits (737), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 80/266 (30%), Positives = 116/266 (43%), Gaps = 16/266 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             VAA Q   T   E+N      L+A+AA   A L  LPE        D D         
Sbjct: 19  FRVAALQMVSTPDRERNLAEAGRLIAEAAAEGAQLVLLPEYFCFMGFKDTDKLAVREPYQ 78

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYDA- 116
           +G     L   ++R+ +  I       +P   R  N  +     GN VARY K+HL++  
Sbjct: 79  DGPIQRFLADAARRHQVWVIGGTLPLMSPEAARVLNTTLVFDPQGNEVARYDKIHLFNFE 138

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               +  E+R +  G E     E    +VGL  CYDLRFPEL          ++V+P+A+
Sbjct: 139 KGEESFDEARTICPGGE-VRTFEAPFGRVGLSVCYDLRFPELYRRMGD--CALVVVPSAF 195

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEM 228
                   HW  LL ARA++  CY++AA + G         G S +IDP+G  +A   E 
Sbjct: 196 TY-TTGRAHWEMLLRARAVENQCYVLAAAQGGKHENGRRTWGHSMLIDPWGEIVAVRDEG 254

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNR 254
             ++   +   R+ +VR  LP   +R
Sbjct: 255 AGVVAGNLERARIDEVRQSLPAWRHR 280


>UniRef50_Q12ZA5 Carbon-nitrogen hydrolase family protein n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12ZA5_METBU
          Length = 270

 Score =  287 bits (737), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 71/269 (26%), Positives = 119/269 (44%), Gaps = 17/269 (6%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +AA Q  +     +KN +       +A    A +  LPE       +  +     A+ 
Sbjct: 10  IKIAAIQMDICHCNKQKNIKKALHFSEEAISKGADIIVLPEVFSTGFCY--EELENIAES 67

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVP---STPGRAWNMLVALQAGNIVARYAKLHLYDA 116
                +  L   SK+N    + +I             N+   L+ G +V  Y K H +  
Sbjct: 68  GSYPTIKELEVFSKKNKCIIVGSIIEKHSSKNRETYTNLGFCLEDGELVGTYTKTHPFG- 126

Query: 117 FAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
              +E     +G+ I P+ L+   + VGL  CY++RFPE+A    L GA+IL+  A +  
Sbjct: 127 ---KEKEYFTSGDVIEPIHLKERDLTVGLQICYEMRFPEIARKLCLSGADILMTIAEFPN 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPAL 231
              +EH W TL  ARA++   + +A    G+       G S IIDP G  IA A +   +
Sbjct: 184 P--REHQWRTLATARAIENQVFHIACNRSGSDPTSTFFGGSMIIDPLGNVIADAKDGECV 241

Query: 232 IMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           I+ E+    +++ R ++PV ++RR    +
Sbjct: 242 IIEEIDTSIMKKTRKEIPVFDDRRPDIYK 270


>UniRef50_A7A823 Putative uncharacterized protein n=2 Tax=Bifidobacterium
           RepID=A7A823_BIFAD
          Length = 277

 Score =  287 bits (736), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 107/259 (41%), Positives = 152/259 (58%), Gaps = 1/259 (0%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M VA GQF VT   E N  I +   ++AA N   +  LPE L+AR D D   +   AQ +
Sbjct: 19  MKVAVGQFTVTEKPEHNINIISGFASEAARNHTRILLLPEGLIARSDDDPHYTADHAQTI 78

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP-GRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           +G F+  LR  S+ N +  + T+H+        +N  + +  G I+  Y K+HLYDAF  
Sbjct: 79  DGPFVTALRGISEANNIAVMGTVHLHEDTVDLPYNCFLVIDHGRILLEYRKIHLYDAFGE 138

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +ES  +  G+E+ PL++++G K G+MTCYD+RFPELA   A+ GA+ LV+ AAW RG  K
Sbjct: 139 RESDSIAPGHEVPPLVDIDGWKFGVMTCYDIRFPELARRHAVAGADALVVSAAWARGEGK 198

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
             HW+TL  ARAL+ TCY++A  E    +IG S ++DP    +A + E   LI A++  +
Sbjct: 199 VDHWTTLCKARALENTCYLMACSEHSGHDIGHSMVVDPAARILAQSGERDELIYADLNRD 258

Query: 240 RVRQVRAQLPVLNNRRFAP 258
           R+  VR  LPVL NRR   
Sbjct: 259 RLEDVRRILPVLKNRRITL 277


>UniRef50_Q7QKM8 AGAP012662-PA (Fragment) n=14 Tax=Neoptera RepID=Q7QKM8_ANOGA
          Length = 308

 Score =  286 bits (734), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 77/273 (28%), Positives = 125/273 (45%), Gaps = 15/273 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  V    EKN +    L+  A  E DA++  LPE   A    D  L   + ++
Sbjct: 34  IKIALIQLRVVDSKEKNLKNAIDLIRIAKKEKDANVVVLPECFNAPYTADT-LLNVAEEI 92

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYDA-- 116
             GE    L   ++   +  +    V S  GR +N   V    G++VA Y K+HL D+  
Sbjct: 93  PTGETCRALSNAARDFGVHVVGGSIVESCSGRLYNTCTVWGPEGDLVATYRKVHLCDSSL 152

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                + E++   AG++ A    V   ++GL  C+D+RF E A A    G ++L+ PA  
Sbjct: 153 SGKMTVAETKLFTAGSKYAT-FTVGETRIGLGICWDMRFAEFATAYRTMGCDLLIYPAVC 211

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
              P  E HW  L  ARALD   ++       + +      G S ++DP+G  I  A+E 
Sbjct: 212 -DVPTGEQHWELLAKARALDNQAFVAFCSPARDTHAKLIPYGHSLVVDPWGRIIQRATEF 270

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
             +++A++  + +  VR ++PV   +R     L
Sbjct: 271 QEIVVADLVLKELTDVRKRIPVFEQKRTDLYDL 303


>UniRef50_A1SD43 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Nocardioides sp. JS614 RepID=A1SD43_NOCSJ
          Length = 261

 Score =  286 bits (733), Expect = 5e-76,   Method: Composition-based stats.
 Identities = 90/258 (34%), Positives = 127/258 (49%), Gaps = 8/258 (3%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +   Q A     E N      L+ +     + L   PEA               A+ L
Sbjct: 10  LRITLVQHASGLEPEAN----RRLLGELTPAGSDLVVFPEAFARDFGDAGSDVSAYAESL 65

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           +G F   + R +     T +  +      P R +N LV    G   A Y K+HLYD+F  
Sbjct: 66  DGPFATEVARVAADRGTTVVAGLFEAGEDPTRPFNTLVL--RGAAEASYRKVHLYDSFGY 123

Query: 120 QESRRVDAGNEIA-PLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           +ES R+ AG      ++EV G +VGLMTCYDLRFPELA      GA++LV+P+AWV GP 
Sbjct: 124 RESDRLTAGPTGPAVVVEVGGFRVGLMTCYDLRFPELARTLVDAGAQLLVVPSAWVAGPR 183

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K  HW TL+ ARA++ T ++ A G+ G +  G S ++DP G  +  A +  A++ A V  
Sbjct: 184 KVDHWRTLVRARAIENTVFVAAVGQPGPRYTGHSMVVDPLGDVLVEAGDEAAVVTATVDL 243

Query: 239 ERVRQVRAQLPVLNNRRF 256
           E +   R   P L NRR 
Sbjct: 244 EALAAARRTNPSLANRRL 261


>UniRef50_A9WV78 Hydrolase, carbon-nitrogen family n=3 Tax=Micrococcaceae
           RepID=A9WV78_RENSM
          Length = 268

 Score =  286 bits (733), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 104/257 (40%), Positives = 142/257 (55%), Gaps = 2/257 (0%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M V+ GQF+     + N E    L A+AA++ + L   PE  +      A     +    
Sbjct: 1   MKVSVGQFSPVGDVDGNIEAMRRLAAEAAQDGSELILFPEEAMFTLGKVAGDFRSAVDAG 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
              F+ +L   +  + +  I   +  S   R +N LVA+   G I+  Y KLHLYDAF+ 
Sbjct: 61  WSVFVQQLTLIAAEHKIAIIAGGYESSGEERPFNTLVAVGSDGAILGTYRKLHLYDAFSY 120

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           QES+R+  GN    ++ V  + VG+MTCYDLRFPELA A A Q  +++ +PAAW +G  K
Sbjct: 121 QESKRIMPGNSGLTVVRVGELNVGMMTCYDLRFPELARALAEQDVDLICVPAAWFKGEHK 180

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPA-LIMAEVTP 238
             HW TLL ARA++ TC++ AAG      IG S I+DP GV  A   E P  L  AEVT 
Sbjct: 181 VDHWETLLKARAIENTCWVAAAGSMSPHCIGHSVILDPMGVPAAFLDEEPESLATAEVTV 240

Query: 239 ERVRQVRAQLPVLNNRR 255
           +R+ +VR  LPVL NRR
Sbjct: 241 KRIEEVREFLPVLKNRR 257


>UniRef50_A6F4Z1 Predicted amidohydrolase n=2 Tax=Marinobacter RepID=A6F4Z1_9ALTE
          Length = 286

 Score =  285 bits (731), Expect = 8e-76,   Method: Composition-based stats.
 Identities = 72/274 (26%), Positives = 120/274 (43%), Gaps = 21/274 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VAA Q   T     N    A L+ +AA+  AS+  LPE              +     +
Sbjct: 15  RVAAIQMVSTHDIAANLNEAARLLKEAADAGASIAVLPENFAVLATKQMIGCGRREAEPD 74

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPST-------PGRAWNMLVALQA-GNIVARYAKLHL 113
                 L +++    +  +      +          R           G  VARY K+HL
Sbjct: 75  NVIRQFLAQQATELGIWVVGGSLPIAARPDWSAVTDRVRACCYVYDDRGREVARYDKIHL 134

Query: 114 YDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +DA         +ES   + G E   +++    ++G+  CYDLRFPEL      Q AE +
Sbjct: 135 FDATVEDAQGQYRESDTFEPG-EDVVVIDTPAGRLGMAICYDLRFPELFRQLREQDAEWV 193

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVTI 222
            LP+A+      + HW  L+ ARA++   ++VAA + G      +  G S I+DP+G  +
Sbjct: 194 SLPSAFTW-YTGDAHWHALIRARAIENQVWLVAAAQGGQNSERRRTYGHSAIVDPWGRIL 252

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           +   E P ++++E+  E ++ +R ++PV  +RR 
Sbjct: 253 SEIDEGPGIVVSELDRETLKDIRTRMPVWEHRRL 286


>UniRef50_D2A1E5 Putative uncharacterized protein GLEAN_07103 n=3 Tax=Coelomata
           RepID=D2A1E5_TRICA
          Length = 445

 Score =  285 bits (731), Expect = 9e-76,   Method: Composition-based stats.
 Identities = 87/279 (31%), Positives = 136/279 (48%), Gaps = 22/279 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  QF  T+  E N +I   L+++AA+  A +  LPEA      +  + +   A+ L G
Sbjct: 8   VAVCQFTATNNKENNLQIVKQLVSEAAQKQAKIVFLPEASDYIAANKNE-AKAFAEPLNG 66

Query: 63  EFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA---- 116
             +   R  +K   +   +   H      + +N  V +   G I + Y KLHL+D     
Sbjct: 67  TLMNEYRNLAKTRKVWLSVGGFHELVNEHQIFNTHVLIDDEGEIKSVYKKLHLFDVSIPE 126

Query: 117 --FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               ++ES   +AG  + P +      + L  CYDLRFPEL++ Q  QGA IL  P+A+ 
Sbjct: 127 LNVNLRESDLNEAGRHLVPPVMTPAGPLALAICYDLRFPELSIIQRKQGANILTYPSAFT 186

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE-M 228
           +      HW TLL +RA++T CY++AA + G  N      GQ+ I+DP G  IA   +  
Sbjct: 187 KAT-GALHWETLLRSRAIETQCYVIAAAQYGKHNEKRTSYGQALIVDPQGKIIAECPKYR 245

Query: 229 PA------LIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
                   + +AE+    +++VR ++PV  +RR    QL
Sbjct: 246 EGHETNQSIAIAEIDSNLIQKVRTEMPVFQHRRSDIYQL 284


>UniRef50_B0KGW5 N-carbamoylputrescine amidase n=60 Tax=Bacteria RepID=B0KGW5_PSEPG
          Length = 298

 Score =  285 bits (731), Expect = 9e-76,   Method: Composition-based stats.
 Identities = 60/283 (21%), Positives = 99/283 (34%), Gaps = 22/283 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
           + +A  Q   +     N +    L+ QAA   A +  L E                  AQ
Sbjct: 4   LRIATTQMPCSWNLPDNLDRAEQLVRQAAAKGAQVILLQELFATPYFCIEQNHQHQALAQ 63

Query: 59  L-LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDA 116
              +   L R    +    +   L+ +  +     +N L      G ++  Y K H+ +A
Sbjct: 64  PYPDSPILQRFAALAGELGVVLPLSWYERAGNA-FFNSLTVADADGRLLGVYRKTHIPNA 122

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
              QE      G+    + +    ++G+  C+D  FPE A   AL GAE+L+ P A    
Sbjct: 123 IGYQEKEYFSPGDTGFKVWDTAFGRLGIGICWDQWFPETARCLALMGAEVLLFPTAIGSE 182

Query: 177 PL-----KEHHWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRIIDPFGV 220
           P         HW   +   A      +VAA   G +             G S I D  G 
Sbjct: 183 PGCAELDSRDHWQVAMRGHAAANLLPVVAANRVGEEVAASDAALAMRFYGSSFICDHKGA 242

Query: 221 TIAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
            +A A  +   + + ++    +R+ R    +  +RR      L
Sbjct: 243 MLAEADRDSSGIWLHDLDLAGMREDRLSWGIFRDRRPEMYATL 285


>UniRef50_Q1PXD4 Similar to N-carbamoyl-D-amino acid hydrolase n=1 Tax=Candidatus
           Kuenenia stuttgartiensis RepID=Q1PXD4_9BACT
          Length = 277

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 80/266 (30%), Positives = 125/266 (46%), Gaps = 16/266 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +AA Q        KN      LM +A +  A L ALPE        + +    + +   G
Sbjct: 6   IAAIQMCSVHDRNKNLNTARVLMEKAVQKGARLIALPENFSFIGQ-ERENITFAEERETG 64

Query: 63  EFLGRLRRESKRNMMTTILTIHVPST--PGRAWNMLVALQ-AGNIVARYAKLHLYDA--- 116
           E +  L++ S ++ +  I       +    +  N  +    +G I+  Y K+HL+D    
Sbjct: 65  EIVHFLKKFSMKHSVAIIGGSVPLRSSSKAKVTNTCLVFDQSGVIIGSYDKIHLFDFHLD 124

Query: 117 --FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ES  V  G  I  + ++ G  +GL  CYDLRFPEL     L+G E+L  P+A+ 
Sbjct: 125 DKTVYRESHYVKHGKHIETV-KLFGHIMGLCICYDLRFPELFRKLMLRGMEVLFAPSAFT 183

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMP 229
               K  HW  LL ARA++  CY+VA  + G  N      G++ IIDP+G  +A   +M 
Sbjct: 184 METGK-DHWEILLRARAIENQCYVVAPAQYGRHNDERISYGRTMIIDPWGRIMAQCQDME 242

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRR 255
            +I+ E+    + +VR +LP L + R
Sbjct: 243 DVIVCEIDFAFLGEVRKRLPCLKHIR 268


>UniRef50_B2J6W4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=11 Tax=Cyanobacteria RepID=B2J6W4_NOSP7
          Length = 270

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 85/266 (31%), Positives = 130/266 (48%), Gaps = 17/266 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
            AA Q        KN      L+  A    A L  LPE      +    L+   A  LE 
Sbjct: 6   AAAIQLTSVPDLHKNLAQAEELIELAVRRGAELVGLPENFSYMGEEKDKLAQGDAIALES 65

Query: 63  EFLGRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVALQA-GNIVARYAKLHLYD---- 115
           E    L++ ++R  +T +           G+ +N  + +   G  ++RY K+HL+D    
Sbjct: 66  E--KFLKKMAQRFQITILGGSFPLPVDNTGKVYNTTLLIDPSGQELSRYYKVHLFDVDVP 123

Query: 116 -AFAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                +ES  V AG ++ P+    +   +GL  CYD+RFPEL    A +GA+++ +PAA+
Sbjct: 124 DGNTYRESSTVVAGTQLPPVHFSEKLGNLGLSICYDVRFPELYRHLAEKGADVIFIPAAF 183

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                 + HW  LL ARA++ T Y++A  + GN        G + IIDP+GV +A A E 
Sbjct: 184 TA-FTGKDHWQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVIIDPWGVILADAGEK 242

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNR 254
           P + +AE+ P R+ QVR Q+P L +R
Sbjct: 243 PGIAIAEIKPTRLEQVRRQMPSLQHR 268


>UniRef50_B8C1M9 Nitrilase n=1 Tax=Thalassiosira pseudonana RepID=B8C1M9_THAPS
          Length = 320

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 71/300 (23%), Positives = 122/300 (40%), Gaps = 44/300 (14%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  QF VT    +N       + +A ++ A L  LPE   +     A      A++L 
Sbjct: 17  RVALLQFHVTHDKPQNINTAREYILKARDSGAQLCVLPEIWNSPYATSA--FGDYAEMLP 74

Query: 62  ------------GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARY 108
                       G     L   ++   M  +      +   + +N  + +   G IV ++
Sbjct: 75  SVGDTFSDKDKWGPSSQMLMELAQSTNMYIVGGSIPETCSDKIFNTCLVVNPKGTIVGKH 134

Query: 109 AKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEG-------MKVGLMTCYDLRFPELA 156
            K+HL+D         +ES  + AG E A   +V G        +VG+  CYD+RFPE A
Sbjct: 135 RKVHLFDVNVPGGIQFKESETLSAG-EGATYFDVAGEDGDSGMGRVGVGICYDIRFPEYA 193

Query: 157 LAQAL-QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG---------- 205
           L        ++L+ P A+        HW  L  ARA+D  C+++ A              
Sbjct: 194 LLLTQIHKCKVLIYPGAFNL-TTGPAHWELLQRARAVDGQCFVLTASPARSNPPLDDEQT 252

Query: 206 --NKN--IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
                   G S ++ P+G  +A   E PA+++A++   +V ++R  +P ++ +R    + 
Sbjct: 253 KHPHYSAWGHSTVVSPWGEVVATCDEHPAVVVADLDMSKVEEMRMAIPTMSQKRSDLYRF 312


>UniRef50_A2BNC1 Predicted amidohydrolase n=1 Tax=Hyperthermus butylicus DSM 5456
           RepID=A2BNC1_HYPBU
          Length = 269

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 84/266 (31%), Positives = 138/266 (51%), Gaps = 5/266 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAE--NDASLFALPEALLA-RDDHDADLSVKSA 57
           + +A  QF  T   E++ E    L+++     ++A L  +PE  +A       +     A
Sbjct: 4   LTIALLQFGATHSKEESLERIRKLISRYERIVSEADLLLVPEYSMADPTGQPPEAIAAIA 63

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQA-GNIVARYAKLHLYD 115
           + LEG ++G   R ++   +  + T++      G+ +N    +   G ++A Y K+HL+D
Sbjct: 64  EPLEGPWIGFFARLAREYSVHVVATLYEKSKAGGKPYNTAALIAPTGELLAVYRKIHLFD 123

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
           A+  +ES     G E A L  ++G ++ L  C+DLRFPEL    ALQGAE++ +PAAW R
Sbjct: 124 AYGYRESDYFMPGAEPAKLATIKGFRIALAVCFDLRFPELFRTYALQGAELVAVPAAWYR 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAE 235
           GP KE     + AARA + T Y+  A +  +   G+S + DP+G+ +  A     ++  E
Sbjct: 184 GPAKEDQLRIIAAARAHENTMYIAVASQYNSNFTGRSLVADPYGLVLLDAGRGEKIVQIE 243

Query: 236 VTPERVRQVRAQLPVLNNRRFAPPQL 261
           V  E + + R QLP+L  RR    +L
Sbjct: 244 VDRESLEEARRQLPLLKLRRPHAYKL 269


>UniRef50_D1Y828 Hydrolase n=1 Tax=Pyramidobacter piscolens W5455 RepID=D1Y828_9BACT
          Length = 275

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 81/271 (29%), Positives = 131/271 (48%), Gaps = 16/271 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            L++  Q    +  + N +     + +AA + A   A+ E          D    SA+ +
Sbjct: 4   FLMSVLQIDSQADKKANLDKIGRFIDEAASHGARFVAMAE--NVHYCGPKDGVFASAETI 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYD-- 115
            G        ++K+  +           PG  R +N  +     G++ ARY K+H+YD  
Sbjct: 62  PGPMSAFFAAKAKQYKIWLHCGSIGEVIPGESRLYNTTLLYNPRGDLAARYEKIHMYDVE 121

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                + +ES     G+ I  + + E  KVGL  CYD+RFPE+    ALQGA+++ +PA 
Sbjct: 122 IENGPSTRESDTKKPGHRIV-VADTEFCKVGLSICYDMRFPEMYRIMALQGAKVMFVPAN 180

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEM 228
           +      + HW  +L  RA++  CY+VA  + G     +  G+S II+P+GVT+A A + 
Sbjct: 181 YTL-FTGKDHWECILKTRAIENQCYVVAPAQIGKKPAFQAYGRSMIINPWGVTVACAEDR 239

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             +I AE+ P+ V Q+R QLP L NR+    
Sbjct: 240 ETIIYAEIDPDYVNQIREQLPSLKNRQPGAY 270


>UniRef50_A8I529 Carbon-nitrogen hydrolase family protein n=8 Tax=Proteobacteria
           RepID=A8I529_AZOC5
          Length = 282

 Score =  284 bits (729), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 77/267 (28%), Positives = 113/267 (42%), Gaps = 15/267 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQA-AENDASLFALPEALLARDDHDADLSVKSAQL 59
           + V+  Q         N    ASL+  A A +   L  LPE      D  A     +   
Sbjct: 15  VKVSLVQMNTQGDKAANLATAASLIEAAVAADKPDLVVLPEYYAFLGDTPAQAQDAAETF 74

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD--- 115
            +GE    ++  +K+  +               +N  V     G  +ARY K+HL+D   
Sbjct: 75  PDGESYQLMKGLAKKLKVAIHAGSVAEREGNSFYNTTVVFGPDGEELARYRKIHLFDVEI 134

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES  V  G ++    E+ G  VG   CYD+RFPEL      +GA+I+VLPAA+
Sbjct: 135 TGGTVYRESDTVSRGEDVVT-YELGGKTVGCAICYDIRFPELFRKLRDKGADIIVLPAAF 193

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK------NIGQSRIIDPFGVTIAAASE 227
                K  HW  L  ARA++T  + +A G+ G          G S +IDP+G   A AS+
Sbjct: 194 TLMTGK-DHWEILARARAIETQTWFLAVGQTGPHAGGKKWCWGHSMVIDPWGHITAQASD 252

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNR 254
                   +      +VRA +PV N+ 
Sbjct: 253 GVGFTTGRLEFGYTEKVRANVPVANHH 279


>UniRef50_C1AA71 N-carbamoylputrescine amidohydrolase n=12 Tax=Bacteria
           RepID=C1AA71_GEMAT
          Length = 307

 Score =  284 bits (729), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 57/293 (19%), Positives = 101/293 (34%), Gaps = 33/293 (11%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSAQ 58
           + +   Q   +     N     + +  AA + A +  L E   A              A+
Sbjct: 5   VTIGIVQDTASDDLASNVTRAVARVRDAASSGAQIICLQELFNAPYFCKTVRPERFDIAE 64

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAF 117
            ++G  +   +  +K   +  ++  +    PG   N    +   G I+  Y K+H+    
Sbjct: 65  PVDGPIVHTFQALAKELAVVIVVPFYEREAPGLYRNSATVIDADGAILGTYRKMHIPHDP 124

Query: 118 AIQESRRVDAGN-------------EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA 164
             +E      G+                 +   +   +G++ C+D  +PE A   +L GA
Sbjct: 125 LFEEKYYFAPGDVTGDQRTDRHPGYNGFRVWRTKYADIGVLICWDQWYPEGARITSLLGA 184

Query: 165 EILVLPAAWVRGPLK--------EHHWSTLLAARALDTTCYMVAAGECGNK--------- 207
           +IL  P A    P +           W T   A A+    ++ +    G +         
Sbjct: 185 QILFYPTAIGWHPAEKPTFGDAQVDAWRTAQRAHAIANGVFVASPNRVGFEPEPGTEGLE 244

Query: 208 NIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
             GQS I DPFG  +A A   P ++ A      + + R   P L +RR     
Sbjct: 245 FFGQSFICDPFGRYLAQAGTEPTILTATCDLGLIEETRRNWPFLRDRRIDAYG 297


>UniRef50_Q5DC61 SJCHGC06938 protein n=1 Tax=Schistosoma japonicum
           RepID=Q5DC61_SCHJA
          Length = 290

 Score =  284 bits (729), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 75/283 (26%), Positives = 121/283 (42%), Gaps = 28/283 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  V +    N +  + L+++A  E+ A L  LPE   +     A      A+ 
Sbjct: 2   LRLALVQMFVGTDKAANLKRASDLISRAVSEHSAQLVCLPECFTS--PIGAKYFEPYAEP 59

Query: 60  LE-GEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLV-ALQAGNIVARYAKLHLYDA 116
           +  G     L   +K + +  +        + G+ +N        G +V  Y KLHL+D 
Sbjct: 60  VPNGPACQMLSNAAKSHKIWLVGGSISERGSDGKIYNCCATYNPDGELVGLYRKLHLFDI 119

Query: 117 -----FAIQESRRVDAGNEIAPLLEVE---------GMKVGLMTCYDLRFPELALAQALQ 162
                F  +ES  + +G E     E+           ++VG+  CYD+RFPEL+L  A Q
Sbjct: 120 DIPGQFTFKESASLSSGKETFS-FEMPLKSSENKISVIRVGIGICYDIRFPELSLLYANQ 178

Query: 163 -GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN---KN--IGQSRIID 216
            G ++L+ PAA+        HW  L  ARALDT CY+       N         +S I  
Sbjct: 179 LGCQLLLFPAAFN-PKTGSLHWELLGRARALDTQCYVGMCSPACNLELDYISYAESLITS 237

Query: 217 PFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           P+G+ IA   +   ++ A +    ++ VR  +P+   RR    
Sbjct: 238 PWGMVIAKGGKEEEILTANLDFSELKHVRESIPIGRQRRLDIY 280


>UniRef50_C7R9G8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7R9G8_KANKD
          Length = 273

 Score =  284 bits (729), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 62/269 (23%), Positives = 113/269 (42%), Gaps = 15/269 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q   +S  + N      L+  AA   A    LPE+    + ++        +  
Sbjct: 5   VKVALIQMTSSSEVDDNLAKAEKLIESAAAQGAQFIVLPESFALMEKYNGQKLEHVERDG 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIH--VPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD-- 115
           +G+    +   +K+  +  +            + +       + G+++A Y K+HL+D  
Sbjct: 65  QGKVQDWMSSLAKKLKLVLVGGTIAVESEIENKPYARCYVYQEDGSLLAHYDKIHLFDVS 124

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                +  ES    AG+E       +G+  G   CYDLRFPEL         ++++ P+A
Sbjct: 125 VKEGESYSESSNTLAGSEPVT-FNWQGITFGCSVCYDLRFPELYRYYQTHNVDVILAPSA 183

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           +     K  HW  LL ARA++   ++VA  + G         G S +IDP+G  I    E
Sbjct: 184 FTLATGKV-HWKLLLQARAVENLAFVVAPNQTGTHDNQRKTFGHSMVIDPWGEVIDELQE 242

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
              + +A +   ++  ++ + PV  +R+ 
Sbjct: 243 DEGISIATLNINKIDMIKEKFPVHLHRKL 271


>UniRef50_Q0F1V1 Hydrolase, carbon-nitrogen family protein n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0F1V1_9PROT
          Length = 272

 Score =  284 bits (728), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 79/265 (29%), Positives = 119/265 (44%), Gaps = 13/265 (4%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M VA  Q    +  E N E  + L+ QAA   A L  LPE         +D  + +    
Sbjct: 6   MRVACIQMNSGADREANLEQASLLLQQAASAGAELAVLPENFSLMGASLSDKRLLAEPQE 65

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP-GRAWNML-VALQAGNIVARYAKLHLY---- 114
               L  L  ++  + M  +    + +    +  N   V    G + A Y K+HL+    
Sbjct: 66  NSTVLAFLSEQAITHRMAIVGGSTLLTGGQDKLRNACPVFSADGRMRAIYDKIHLFDVDL 125

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
           D  +  ES  V AG     +  +   + GL  CYD+RFPEL    A  G +++ + AA+ 
Sbjct: 126 DGESYHESESVVAGEHPCSVA-LGDFRFGLSICYDIRFPELYRHYADSGCDVVCVVAAFT 184

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW TLL ARA++  CY++A+ + G         G S IIDP+G  +A   E  
Sbjct: 185 EQT-GHAHWQTLLRARAIENQCYLLASAQWGVHADGRRTWGHSMIIDPWGEVMALQEEST 243

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNR 254
            +IMA++T  R+  +R  LP L +R
Sbjct: 244 GVIMADLTSARLAHIRKILPSLQHR 268


>UniRef50_UPI0000E7FA0A PREDICTED: hypothetical protein isoform 1 n=1 Tax=Gallus gallus
           RepID=UPI0000E7FA0A
          Length = 250

 Score =  284 bits (728), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 53/272 (19%), Positives = 107/272 (39%), Gaps = 40/272 (14%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +A  Q  V++V   N +    L+ +A+   A + ALPE   +          + A+ +
Sbjct: 4   FRLALIQLHVSAVKSDNLQRACGLIREASAKGAKVVALPECFNSPY--GTQYFKEYAEKI 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYD---- 115
            GE   +L   +K   +  +         G+ +N   V    G I+A++ K+HL+D    
Sbjct: 62  PGESTQKLSAVAKECSIYLVGGSIPEEDGGKLYNTCTVFGPDGAILAKHRKIHLFDINVP 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ES  +  G+    + +                            ++L+ P A+ 
Sbjct: 122 GKIQFKESETLSPGDS-FSMFDTR-------------------------CQLLIYPGAFN 155

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  L   RA+D   Y+       ++       G S +++P+G  IA A    
Sbjct: 156 M-TTGPAHWELLQRGRAVDNQVYVATVSPARDEKASYVAWGHSTVVNPWGEVIAKAGAEE 214

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            +I  ++  +++ ++R Q+P+L+ +R+    +
Sbjct: 215 TVIYTDIDLKKLAEIRQQIPILSQKRYDLYGI 246


>UniRef50_A5GT50 Possible nitrilase n=5 Tax=Bacteria RepID=A5GT50_SYNR3
          Length = 272

 Score =  284 bits (728), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 82/271 (30%), Positives = 130/271 (47%), Gaps = 16/271 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            L AA Q   T   + N      L+  AA   A L  LPE        +  L  + A  L
Sbjct: 4   FLAAALQCTSTPDPDSNFAQIEELIDLAARRGAELVGLPENFAFLGAENKRL--ELAPTL 61

Query: 61  EGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWNML-VALQAGNIVARYAKLHLYD--- 115
                  L   ++R  +  +     VP+     +N   +  + G ++A Y K+HL+D   
Sbjct: 62  AERCSRFLVTMARRYQVAILGGGFPVPAGEAATFNRSELVSRDGQVLATYDKIHLFDVDL 121

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEG-MKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  ES  + AG+ + P+ ++ G  +VGL  CYD+RFPEL    A  GAE+L++PAA
Sbjct: 122 PDGNTYTESDTITAGSSLPPVADLPGLCRVGLSICYDVRFPELYRHLAGAGAELLMVPAA 181

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++ T Y++A  + G         G + +IDP+G  +A A  
Sbjct: 182 FTA-YTGKDHWQVLLQARAIENTSYVLAPAQTGLHYGRRQSHGHALVIDPWGTVLADAGV 240

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
            P + +A +  + ++++RAQ+P L +RR A 
Sbjct: 241 GPGVAIAPIDTDHLQRIRAQMPSLRHRRPAL 271


>UniRef50_Q1QX75 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=44 Tax=Bacteria RepID=Q1QX75_CHRSD
          Length = 299

 Score =  284 bits (727), Expect = 3e-75,   Method: Composition-based stats.
 Identities = 59/286 (20%), Positives = 101/286 (35%), Gaps = 26/286 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
           + V   Q A      ++     + +   A   A+L  L E          + D     A+
Sbjct: 5   LKVGLVQQAAWPDKARSLAESEAGIRALAAQGATLVLLQELHATHYFCQTEDDTLFDLAE 64

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG-NIVARYAKLHLYDAF 117
            L+G    RL   +    +  + ++      G   N  V        V  Y K+H+ D  
Sbjct: 65  PLDGPSAQRLAALAAELDIVLVGSLFERRAAGLYHNTAVVFDRQQGRVGYYRKMHIPDDP 124

Query: 118 AIQESRRVDAGNE----IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
              E      G+         ++    ++GL+ C+D  +PE A   AL GA++L+ P A 
Sbjct: 125 GFYEKFYFTPGDAEADAGFEPIDTSVGRLGLLVCWDQWYPEAARLMALAGADLLLYPTAI 184

Query: 174 VRGPLKE--------HHWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRI 214
              P             W+ +  +  +     ++ A   G++             G S +
Sbjct: 185 GWTPTDAPEEKQRQKDAWTLIQRSHGVANGLPVLVANRVGHEPDPSGASPGIDFWGGSFV 244

Query: 215 IDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
             P G  +A A + PA ++ +V   R  QVR   P L +RR     
Sbjct: 245 CGPQGELLAQADDAPAHLLVDVDLSRSEQVRRVWPYLRDRRIDAYD 290


>UniRef50_Q724C2 Hydrolase, carbon-nitrogen family n=20 Tax=Bacilli
           RepID=Q724C2_LISMF
          Length = 259

 Score =  283 bits (726), Expect = 3e-75,   Method: Composition-based stats.
 Identities = 68/264 (25%), Positives = 111/264 (42%), Gaps = 13/264 (4%)

Query: 2   LVAAGQFAVTSV-WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            +A  Q  V     + N       + +AA+N A +  LPE        +       A L 
Sbjct: 3   KLALCQTDVVFKYPDANYARIEKAIVEAAKNGADIAVLPEMWNTGYALN--ELAGVADLN 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAI 119
                  L   S+++ +  I      S   +  N + A    G +++ Y K+HL+    +
Sbjct: 61  GERTKEFLATLSEKHQIAIIGGSVSISEGTKFSNTMYAFDKYGGLLSSYKKVHLFQL--M 118

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E   ++AGN+   L  ++G+      CYD+RFPE       +G+E++ + A W     +
Sbjct: 119 NEHLYLEAGND-TNLFRLDGVSCAGFICYDIRFPEWIRKHTSEGSEVIFVSAQWPAE--R 175

Query: 180 EHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMAE 235
              W  LL ARA++   ++VA    G    N   G S +IDP G  +A   E    I AE
Sbjct: 176 VTQWEQLLIARAIENQAFVVAVNRVGDDPNNHFNGHSLVIDPLGNIVAHGGEDEGNIYAE 235

Query: 236 VTPERVRQVRAQLPVLNNRRFAPP 259
           +  + V + R  +PV  +RR    
Sbjct: 236 IDLKLVAETRGIIPVFTDRRPELY 259


>UniRef50_C6JLR5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Fusobacterium varium ATCC 27725
           RepID=C6JLR5_FUSVA
          Length = 274

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 67/271 (24%), Positives = 119/271 (43%), Gaps = 16/271 (5%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDA--SLFALPEALLARDDHDADLSVK-S 56
           +  A  Q  +     E N +   +L  +A +      +  LPE             ++  
Sbjct: 2   LNFALLQTNIKFCDAEYNFKNVKNLFKEAMKYKPTPDVVVLPEDWSYGFSDKMFHDMENY 61

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTIHVPST--PGRAWNMLVAL-QAGNIVARYAKLHL 113
            +   G  +  L+  +K   +  +       +   G+  N    + + G I+A Y+K+HL
Sbjct: 62  CEAENGPSVSILKELAKEYKVFVVAGSIATKSSKDGKIRNTTFLINRNGEIIADYSKMHL 121

Query: 114 YDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
           Y    + E+  +++GN+   ++E E  K G M CYD+RF EL+   AL+GAE +++ + +
Sbjct: 122 YSD--MDENFMIESGNKA-EVVETEIGKFGFMICYDIRFCELSRIYALKGAEAIIVTSDF 178

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMP 229
                + +HW TLL ARA++   +++A    G        G S IIDP+G  IA   E  
Sbjct: 179 PNP--RVNHWRTLLQARAIENQMFVIACNRVGESPMGSYCGHSLIIDPWGEIIAEGGEKE 236

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            +I   V    +  +R  + V  +R     +
Sbjct: 237 EIIHGSVDLSVIHNIRETIHVFRDRHPEFYE 267


>UniRef50_C2BXL2 Cyanide hydratase n=1 Tax=Listeria grayi DSM 20601
           RepID=C2BXL2_LISGR
          Length = 268

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 72/265 (27%), Positives = 112/265 (42%), Gaps = 13/265 (4%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q  V     +KN +     + +AA + A +  LPE                A  
Sbjct: 10  MKIALCQTDVAFRDPDKNYQAIEQAVIEAANSGADIVVLPEMWNTGYCLS--ELADFADP 67

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLV-ALQAGNIVARYAKLHLYDAFA 118
                 G L R + +  +T I      S      N++    + G+++A Y K+H +    
Sbjct: 68  NGDRTKGFLIRLALQQKVTIIGGSVAISEEDHFSNIMYAVAKDGDLLASYRKVHPFQ--G 125

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E   +  GN    L  +  +      CYD+RFPE     A  GAE+L + A W     
Sbjct: 126 MDEHTYIRPGNSA-NLFRIGDLACAGFICYDIRFPEWLRKHAANGAEVLFVSAQWPSA-- 182

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMA 234
           +   W  LL ARA++   ++VA    G    N+  G S +I P G  IA A + P  ++A
Sbjct: 183 RITQWKQLLIARAIENQAFVVAVNRVGSDPANQFGGNSLVIHPSGEIIAEADDTPQNLLA 242

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
           E+    V++VR  +PVL +RR    
Sbjct: 243 EINLADVKKVREAMPVLADRRPELY 267


>UniRef50_P55175 UPF0012 hydrolase sll0601 n=46 Tax=Cyanobacteria RepID=Y601_SYNY3
          Length = 272

 Score =  283 bits (725), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 85/267 (31%), Positives = 129/267 (48%), Gaps = 18/267 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
            AA Q        +N +    L+  A    A L  LPE        +    ++ A  +  
Sbjct: 6   AAALQMTSRPNLTENLQEAEELIDLAVRQGAELVGLPENFA--FLGNETEKLEQATAIAT 63

Query: 63  EFLGRLRRESKRNMMTTILT---IHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
                L+  ++R  +T +       V    G+A+N    +   G  +ARY K+HL+D   
Sbjct: 64  ATEKFLQTMAQRFQVTILAGGFPFPVAGEAGKAYNTATLIAPNGQELARYHKVHLFDVNV 123

Query: 116 --AFAIQESRRVDAGNEIAPLLEVE-GMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  ES  V AG +  P+   +    +GL  CYD+RFPEL    + QGA++L +PAA
Sbjct: 124 PDGNTYWESATVMAGQKYPPVYHSDSFGNLGLSICYDVRFPELYRYLSRQGADVLFVPAA 183

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +      + HW  LL ARA++ TCY++A  + G         G + IIDP+GV +A A E
Sbjct: 184 FTA-YTGKDHWQVLLQARAIENTCYVIAPAQTGCHYERRHTHGHAMIIDPWGVILADAGE 242

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNR 254
            P L +AE+ P+R++QVR Q+P L +R
Sbjct: 243 KPGLAIAEINPDRLKQVRQQMPSLQHR 269


>UniRef50_A3ZLM3 Putative nitrilase n=1 Tax=Blastopirellula marina DSM 3645
           RepID=A3ZLM3_9PLAN
          Length = 258

 Score =  283 bits (725), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 75/261 (28%), Positives = 122/261 (46%), Gaps = 17/261 (6%)

Query: 8   FAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGR 67
                  E N +    L+AQAAE  A L  LPE          +  V+ A+ + G    R
Sbjct: 1   MNAGEDKELNLQTAERLIAQAAERGAQLVVLPELFN--YLGRLENLVEHAETISGPTAVR 58

Query: 68  LRRESKRNMMTTILTIHVPST--PGRAWNMLVALQA-GNIVARYAKLHLYD----AFAIQ 120
           +R+ + ++ +  +       +    R +N  +     G  +  Y K+HL+D       + 
Sbjct: 59  MRKAALKHQIYLVAGSFAERSETESRVFNTSLIFDPLGKQIGVYRKIHLFDIDLPDVQVH 118

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES  V  G+E   L +     V    CYDLRFPE+  +  L+    L LPAA+       
Sbjct: 119 ESSFVAPGSE-VSLCQTALGGVAQAICYDLRFPEIVRSYDLEKVACLALPAAFTA-KTGA 176

Query: 181 HHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAA-SEMPALIMA 234
            HW  L+ +RA++   +++AA + G      ++ G S I+DP+G  +A A  +   +I A
Sbjct: 177 AHWQILVRSRAIENQLFLIAANQYGRYTNGIQSYGHSLIVDPWGTILAEAGGDAEEVITA 236

Query: 235 EVTPERVRQVRAQLPVLNNRR 255
           E++ ER+R+VR  +P L +RR
Sbjct: 237 EISLERLREVRQHMPALRHRR 257


>UniRef50_Q5WM18 Methylthioribose recycling protein n=3 Tax=Bacillales
           RepID=Q5WM18_BACSK
          Length = 275

 Score =  283 bits (725), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 70/272 (25%), Positives = 120/272 (44%), Gaps = 20/272 (7%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASL-----FALPEALLARDDHDADLSV 54
           M VA  Q  V     ++N E   + + Q       L       LPE          +   
Sbjct: 12  MHVAVFQMEVLAGKPDENRERVKTWVEQLCRE--QLERPLTIVLPELWTTGYQL--EDLG 67

Query: 55  KSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHL 113
           + A+    E +  L++ ++ + +  +         G  +N  + +   G +V  Y K+HL
Sbjct: 68  ELAEEEGVETIAFLQQLARAHRIHMVAGSIATKKDGGIYNTALVIDAQGKLVYTYDKVHL 127

Query: 114 YDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                + E   +  G+    L E++G+K+ ++ CYDLRFPELA   AL+GAE+L + A W
Sbjct: 128 --VPMLNEPAYMQGGSVPPALFELDGVKMAVLICYDLRFPELARRLALEGAEVLFIVAEW 185

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAA-SEM 228
                +  HW  L  ARA++   Y+++    G+       G S +IDP+G  I    S  
Sbjct: 186 PLA--RAMHWKALQQARAIENQFYLLSCNSVGSHNGTDYAGTSMVIDPWGEIIVEGSSTE 243

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
              +  +V   +  +VR ++PV ++RR    +
Sbjct: 244 EEWLQCKVDFSKAAEVRDRVPVFSSRRPDLYR 275


>UniRef50_B6YW48 Carbon-nitrogen hydrolase n=4 Tax=cellular organisms
           RepID=B6YW48_THEON
          Length = 264

 Score =  283 bits (725), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 70/273 (25%), Positives = 112/273 (41%), Gaps = 21/273 (7%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVK--SA 57
           M VA  Q        EKN      L+ +AA+  A L  LPE      + ++   V+  + 
Sbjct: 1   MRVAYVQMEPKLLEPEKNYSKAERLIKEAAKEGAKLVVLPELFDTGYNFESRDEVESVAG 60

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-G-NIVARYAKLHLYD 115
           Q+ +GE    L   ++   +  +         GR +N  V +   G   + +Y K+HL+ 
Sbjct: 61  QIPDGETTEFLVELARDLEVFIVAGTAEKDEKGRLYNSAVIVGPIGWGYIGKYRKVHLF- 119

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +E    ++GN    +  +  +KVG+M C+D  FPE A   AL+GAEI+  P+  V 
Sbjct: 120 ---YREKLFFESGNLGFHVFNIGIVKVGVMICFDWFFPESARTLALKGAEIIAHPSNLVM 176

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEM-PA 230
                      +  RAL+   Y + A   G +     IG+S I  P    +A  SE    
Sbjct: 177 PYAPRA-----MPIRALENRVYTITANRIGEERGLRFIGKSTIASPKAEVLAVGSEDMEE 231

Query: 231 LIMAEVTPERVRQVR--AQLPVLNNRRFAPPQL 261
           + + E+     R  R      +  +RR     L
Sbjct: 232 IGVVEIDLNLTRDKRLNELNDIFKDRRPEFYLL 264


>UniRef50_A4J4S3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfotomaculum reducens MI-1
           RepID=A4J4S3_DESRM
          Length = 273

 Score =  282 bits (724), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 70/272 (25%), Positives = 113/272 (41%), Gaps = 17/272 (6%)

Query: 1   MLVAAGQF-AVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSA 57
           + +   Q   V      N       + QAA   A +  LPE        D   D   +  
Sbjct: 5   LTIGLIQMDCVLGDVAANVAKAIERIRQAAAMGAQIICLPELCTTGYRPDLLEDKLWELT 64

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPST-PGRAWNMLVALQ-AGNIVARYAKLHLYD 115
           + + G       + +K   +  IL ++     PG   N  V +   G +   + K H   
Sbjct: 65  EPVPGPTTDVFSQLAKELGIYIILPMNEKGAVPGMIHNSAVFIDKDGEVQGVFRKAH--- 121

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
                E      GN   P+ + E  KVG+M CYD+ FPE+A    L+GAE++  P+AW +
Sbjct: 122 -AYATERYYFTDGNH-YPVFQTEFGKVGVMICYDMGFPEVARILTLKGAEVIFAPSAWRQ 179

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASE-MPA 230
               E  W   +AARAL+   ++ A    G +      G+S+I +  G T+A A+     
Sbjct: 180 E--DEDIWDINIAARALENRLFVAAVNRVGREGDVVMHGKSKIANTRGKTLAEAARFEED 237

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           +++A V    +   R + P L +R+ A   L+
Sbjct: 238 ILVATVDLHELIAGRRETPYLKDRKPASYGLI 269


>UniRef50_B5JWE9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=gamma proteobacterium HTCC5015
           RepID=B5JWE9_9GAMM
          Length = 282

 Score =  282 bits (723), Expect = 9e-75,   Method: Composition-based stats.
 Identities = 80/268 (29%), Positives = 115/268 (42%), Gaps = 16/268 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q   T   E N      L+A AAE  A +  LPE      D        +    +G
Sbjct: 12  IACVQMTTTDSVEHNLATAQRLVANAAERGAQIVVLPETFAFMGDEITQQFGVAEAFGDG 71

Query: 63  EFLGRLRRESKRNMMTTILTIHV---PSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
                +   +K N +  +         S   R     +     G   ARY K+HL+D   
Sbjct: 72  PIQTAVADWAKSNHVWIVAGTIPLRHESDRERVRAACLVFDDSGQCQARYDKVHLFDVEL 131

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES     G+EIA +L+    ++G+  CYDLRFPEL  AQ   G E  VLP+A+
Sbjct: 132 PTGESYKESSVFLPGDEIA-VLDTPLGRMGVAVCYDLRFPELFRAQLDMGMEFCVLPSAF 190

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI-----GQSRIIDPFGVTIAAASEM 228
                 + HW  LL ARA++  CY  AA + G         G S I+DP+G  +   +E 
Sbjct: 191 TEAT-GQAHWLPLLQARAVENLCYFAAAAQVGEHGSGRRTHGHSVILDPWGQVVDQLAEG 249

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
             +++  +  E  R  RA  P L +RR 
Sbjct: 250 EGVVVGSIDMEHQRLTRANFPALQHRRL 277


>UniRef50_C7ICC9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Clostridium papyrosolvens DSM 2782
           RepID=C7ICC9_9CLOT
          Length = 267

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 70/262 (26%), Positives = 119/262 (45%), Gaps = 16/262 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ-L 59
           + +   Q  V+   + N E   S++ + ++  A +  LPE  +     D  L    A+ +
Sbjct: 5   IRLGLCQMTVSDKKKDNLEKALSMLEECSKQGADIAILPEMFICPY--DTKLFPLYAENV 62

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
              + L  + + +K N M  +      S  G  +N  V     GN +A++ K+HL+D   
Sbjct: 63  ENSKTLSVISKSAKYNNMYIVAGTIPESNNGFIYNSSVMFDRQGNTIAKHRKVHLFDINV 122

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES  + AG     + E E   +GL  C+D+RF  L      +GA+I++ PA++
Sbjct: 123 KDGISFRESDVLTAGRS-VTVAETEFGCIGLAICFDMRFAGLYSEMTEKGAKIIITPASF 181

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                   HW  L+ ARALD   + VA       +      G S + DP+G  I+ A E 
Sbjct: 182 NM-TTGPAHWELLVRARALDNQVFHVAVSSARETSANYVSYGNSMVCDPWGSVISRAEEK 240

Query: 229 PALIMAEVTPERVRQVRAQLPV 250
             +++A++    V  VR Q+PV
Sbjct: 241 EDILIADIDLNMVNSVRNQIPV 262


>UniRef50_Q15NS3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=13 Tax=Bacteria RepID=Q15NS3_PSEA6
          Length = 302

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 59/284 (20%), Positives = 104/284 (36%), Gaps = 24/284 (8%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDAD--LSVKSA 57
           + V   Q AV +   + + +  A  + + AE    L  L E          +       A
Sbjct: 11  LKVGVVQQAVANNDKQLSWQRSAEQVTKLAEQGCELVMLQELHSTLYFCQQENTDFFDLA 70

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG-NIVARYAKLHLYDA 116
           + + G         + +  +  I ++      G   N  V       +V +Y K+H+ D 
Sbjct: 71  EPIPGPATDYFSELAAKLDIVLITSLFEKRGSGLYHNTAVVFDRQLGMVGKYRKMHIPDD 130

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW--- 173
               E      G+     ++    K+G++ C+D  +PE A   A++GA++L  P A    
Sbjct: 131 PGFYEKFYFTPGDMGFEPIQTSVGKLGVLVCWDQWYPEAARLMAMRGADMLFYPTAIGWD 190

Query: 174 VRGPLKEHH-----WSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRIIDP 217
               + E       W T+  + A+  +  +V A   G +             GQS I  P
Sbjct: 191 PADTVDEQQRQFGAWQTIQRSHAVANSVPVVVANRTGFEASPVEGDNGIQFWGQSFIAGP 250

Query: 218 FGVTIAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            G  +A A  +    +M E+   R  QV+   P   +RR    +
Sbjct: 251 QGEILAQADADSEQNLMVELDLARTEQVKRIWPYFRDRRIDAYE 294


>UniRef50_UPI0001B416B7 carbon-nitrogen hydrolase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI0001B416B7
          Length = 271

 Score =  281 bits (721), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 74/261 (28%), Positives = 128/261 (49%), Gaps = 2/261 (0%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A  Q    +  + +          AA N A L   PE  +       D  +++A++L
Sbjct: 13  VKIALTQLKPVADKDVSLRNIEYYAGTAAANSADLIVFPEYYMF-YSQYKDAIIRNAEVL 71

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
            G ++ R++  S+ N +  I  I+        ++  V +  G ++  Y K HLYDAF  +
Sbjct: 72  NGNYIKRIKEISRTNKIGIITGINEVY-DHNYYDTAVYVNDGELLNYYRKSHLYDAFGYR 130

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES     GN    + ++  +  G++ CYD+RFPE+    +L  A++++L +AW  GP+KE
Sbjct: 131 ESDIYTYGNGPFKISKIGNINFGMLICYDIRFPEVFRNYSLNDADMVILISAWFAGPIKE 190

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
             W +L++ RAL+ T Y+  +   G    G +   DP G  I  A+E   +I + +   R
Sbjct: 191 EQWLSLVSTRALENTTYLATSNMIGGGFTGITTFTDPIGAIINRAAEDEDIIYSIIDTNR 250

Query: 241 VRQVRAQLPVLNNRRFAPPQL 261
           +  VR ++PVL  RR    +L
Sbjct: 251 ISTVRKKMPVLKQRRPELYKL 271


>UniRef50_Q8VYF5 N-carbamoylputrescine amidase n=162 Tax=cellular organisms
           RepID=AGUB_ARATH
          Length = 326

 Score =  281 bits (721), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 60/308 (19%), Positives = 109/308 (35%), Gaps = 48/308 (15%)

Query: 3   VAAGQFAVTSVWEKNAEICAS---------------------------LMAQAAENDASL 35
           V++ QFA +     N                                 L+ +A    A++
Sbjct: 12  VSSLQFACSDDISTNVAAAERFVSLSSSLPLSNYQSLPSSSSFKFPYALVREAHAKGANI 71

Query: 36  FALPEALLARDD--HDADLSVKSAQLL-EGEFLGRLRRESKRNMMTTILTIHVPSTPGRA 92
             + E            +   K A+       + R+++ +K   +   ++    +     
Sbjct: 72  ILIQELFEGYYFCQAQREDFFKRAKPYKNHPTIARMQKLAKELGVVIPVSFFEEANTAHY 131

Query: 93  WNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRF 152
            ++ +    G  +  Y K H+ D    QE    + G+    + + +  K+G+  C+D  F
Sbjct: 132 NSIAIIDADGTDLGIYRKSHIPDGPGYQEKFYFNPGDTGFKVFQTKFAKIGVAICWDQWF 191

Query: 153 PELALAQALQGAEILVLPAAWVRGP-----LKEHHWSTLLAARALDTTCYMVAAGECGNK 207
           PE A A  LQGAEIL  P A    P         HW  ++   A      +VA+   G +
Sbjct: 192 PEAARAMVLQGAEILFYPTAIGSEPQDQGLDSRDHWRRVMQGHAGANVVPLVASNRIGKE 251

Query: 208 ------------NIGQSRIIDPFGVTIAAASEM-PALIMAEVTPERVRQVRAQLPVLNNR 254
                         G S I  P G  +A A +   A+++A+   + ++  R    V  +R
Sbjct: 252 IIETEHGPSQITFYGTSFIAGPTGEIVAEADDKSEAVLVAQFDLDMIKSKRQSWGVFRDR 311

Query: 255 RFAPPQLL 262
           R    ++L
Sbjct: 312 RPDLYKVL 319


>UniRef50_A7I5W9 Porphyromonas-type peptidyl-arginine deiminase n=4
           Tax=Methanomicrobia RepID=A7I5W9_METB6
          Length = 640

 Score =  281 bits (721), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 64/273 (23%), Positives = 100/273 (36%), Gaps = 15/273 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA--DLSVKSAQL 59
            +A  Q  +    ++N       + +AA+N A    LPE    R             A+ 
Sbjct: 7   TIALIQMEIGPDPDRNLNEARERVEKAAQNGAQFICLPELFRTRYFPQQIGTPVQSLAET 66

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
           + GE      R +K      I+ +   S  G   N  V +   G++ A Y K+H+     
Sbjct: 67  IPGESTDVFTRIAKEYKAVIIVPVFERSPLGHLENAAVVIDADGSLHAPYYKVHIPQDPK 126

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E      GN  A +      K+ ++ CYD  FPE A   +L+GAEI+  P A      
Sbjct: 127 FFEKGYFYPGNHYA-VHATRYGKIAVLICYDQWFPEAARCVSLEGAEIIFYPTAIGNPCT 185

Query: 179 KE-------HHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASE 227
           ++         W  +  + A+  + ++ A    G +      G S I D FG  +A A +
Sbjct: 186 EQPSEGDWQEAWEIIQRSHAIANSVHIAAVNRAGGEGNIRFFGGSFICDAFGKVLARAGD 245

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
               I A    E    +R       NRR     
Sbjct: 246 ANETITATADLELNESIRDSWGFFRNRRPDTYG 278


>UniRef50_Q1LEX6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Cupriavidus metallidurans CH34
           RepID=Q1LEX6_RALME
          Length = 278

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 16/271 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q       E N       +  AA + A L   PE    R   DA+    +A  +
Sbjct: 4   IKVAAIQIDSRQDREANLAALEHWILAAASDGAKLIVTPEYSDVRG--DANALQAAASAV 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLV-ALQAGNIVARYAKLHLYDAF 117
            G     +   ++R      L       PG  R  N  +     G I ARY K+HLYDA 
Sbjct: 62  PGPVSEHISSLAQRTGCWIHLGSMHERLPGETRLGNSGITFAPDGGIAARYRKVHLYDAV 121

Query: 118 A----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES     G+ +  + +  G+ +GL  CYDLRF EL      +GA +L++PAA+
Sbjct: 122 VNGKPYRESADFAPGDGLHTV-DAAGLTLGLSICYDLRFGELYRTLRARGANVLLVPAAF 180

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEM 228
                +  HW TLL ARA++  CY++AA + G        +G+S IIDP+G  +A   + 
Sbjct: 181 NVHTGR-DHWETLLRARAIENQCYVIAAAQIGGPGPALPCLGRSMIIDPWGTVLACMPDT 239

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
              I AE+  ERV  +R  LP   +RR    
Sbjct: 240 TGFITAELDTERVAGLREALPAWEHRRTDLY 270


>UniRef50_C4QCM8 Nitrilase-related n=1 Tax=Schistosoma mansoni RepID=C4QCM8_SCHMA
          Length = 541

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 77/283 (27%), Positives = 121/283 (42%), Gaps = 28/283 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  V +    N +  + L+++A  E+   L  LPE   +     A      A+ 
Sbjct: 253 LRLALVQMFVGADKPANIKRASELISRAVSEHSPHLVCLPECFTS--PIGAKYFGPYAEA 310

Query: 60  LE-GEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLV-ALQAGNIVARYAKLHLYDA 116
           +  G     L   +K + +  +          G+ +N        G +V  Y KLHL+D 
Sbjct: 311 VPNGPSCQMLSDAAKLHKIWLVGGSIPERGPDGKLYNCCATYNPDGELVGLYRKLHLFDI 370

Query: 117 -----FAIQESRRVDAGNEIAPLLEVE---------GMKVGLMTCYDLRFPELALAQALQ 162
                FA +ES  + +G E     E+           ++VG+  CYD+RFPEL+L  A Q
Sbjct: 371 DIPGQFAFKESASLSSGKETFS-FEIPLKNSENKISVIRVGIGICYDIRFPELSLLYANQ 429

Query: 163 -GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN---KNIGQ--SRIID 216
            G ++L+ PAA+        HW  L  ARALDT CY+       N     I    S I  
Sbjct: 430 LGCQLLLFPAAFN-PKTGSLHWELLGRARALDTQCYVGMCSPACNLELDYISHAESLITS 488

Query: 217 PFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           P+G+ IA   +   +I A++    ++ VR  +P+   RR    
Sbjct: 489 PWGIVIAKGGKEEEIITADLDFSELKCVRESIPIGRQRRLDIY 531


>UniRef50_Q94JV5 AT4g08790/T32A17_100 n=10 Tax=Viridiplantae RepID=Q94JV5_ARATH
          Length = 307

 Score =  281 bits (719), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 72/269 (26%), Positives = 124/269 (46%), Gaps = 18/269 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q    +    N   C+ L+ +AA   A L   PE      D + +   K A+ L
Sbjct: 37  VRVAAAQMTSVNDLMTNFATCSRLVQEAALAGAKLICFPENFSFVGDKEGESV-KIAEPL 95

Query: 61  EGEFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
           +G  + R    ++ + +   +             N  V +   G I   Y K+HL+D   
Sbjct: 96  DGPVMERYCSLARDSNIWLSLGGFQERFDDTHLCNTHVVIDDAGMIRDTYQKMHLFDVDV 155

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA-LQGAEILVLPAA 172
               + +ES     G +I  + +    ++GL  CYDLRFP++       Q A++L++P+A
Sbjct: 156 PGGSSYKESSFTVPGTKIVSV-DSPVGRLGLTVCYDLRFPKIYQQLRFEQKAQVLLVPSA 214

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW  LL ARA++T CY++AA + G  N      G + IIDP+G  +    +
Sbjct: 215 FTK-VTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDTLIIDPWGTVVGRLPD 273

Query: 228 M--PALIMAEVTPERVRQVRAQLPVLNNR 254
                +++A++    +  VR ++P+   R
Sbjct: 274 RVSTGIVVADIDFSLIDSVRTKMPIDKQR 302


>UniRef50_A5V962 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Sphingomonas wittichii RW1 RepID=A5V962_SPHWW
          Length = 268

 Score =  280 bits (718), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 81/268 (30%), Positives = 126/268 (47%), Gaps = 19/268 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEAL--LARDDHDADLSVKSAQ 58
           M +   Q  V    E N       + + A +   +  LPE    L            +A+
Sbjct: 1   MKIGVVQINVGMDKEANIARLDRQVRRLAADGCDIVFLPEMAMALTG---KPAALQAAAE 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLH----- 112
             +G ++  ++  +K   +   L   +     R  N  +     G  + RY+KLH     
Sbjct: 58  AEDGAYVTAMKALAKECGINLHLGSFMERRGDRFLNTSLVFDRQGECIGRYSKLHRFDID 117

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
           L D  AI+ES  VD G+ I  ++++EG+KV L  CYDLRFPEL  A    GA+++ +PAA
Sbjct: 118 LPDGTAIRESDVVDRGDAI-TVVDIEGLKVALTICYDLRFPELFRALVDLGADLITVPAA 176

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECG------NKNIGQSRIIDPFGVTIAAAS 226
           +        HW  LL ARA++T CY+ A G+ G        N G S IIDP+G  +  AS
Sbjct: 177 FTFQT-GADHWEVLLRARAIETECYIAAPGQVGGFDDGKYLNFGHSMIIDPWGTVVGQAS 235

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNR 254
               +  A +  + ++ VRA++P+  +R
Sbjct: 236 NGEGVASAVIDRDYIQTVRARIPLRKHR 263


>UniRef50_A4ALG5 Putative hydrolase n=1 Tax=marine actinobacterium PHSC20C1
           RepID=A4ALG5_9ACTN
          Length = 271

 Score =  280 bits (717), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 93/260 (35%), Positives = 135/260 (51%), Gaps = 3/260 (1%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  QFA  +  ++N      L  +A E  A+    PE          D  + +A+ L+
Sbjct: 6   TVAVAQFAPGADRDENIATVTQLAERAVERGANFVVFPEYSAYFTPTMGDDWLAAAEPLD 65

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAW-NMLVALQA-GNIVARYAKLHLYDAFAI 119
           G F+  L   ++R  +     +   +   + + N LVA+   G +VA Y K HLYDAF  
Sbjct: 66  GPFVQALTSLAQRLRIHVAAGMLESADEEKRFSNTLVAIAPTGAVVATYRKQHLYDAFGQ 125

Query: 120 QESRRVDAGNEIAP-LLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           +ES  V  G+  AP     EG  VGL TCYD+RFPE++      GA ++V+PA WVRGPL
Sbjct: 126 RESDWVIPGSIGAPETFTWEGFTVGLQTCYDIRFPEVSRRLVDAGANLIVVPAEWVRGPL 185

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           KE+HW TLL ARA++ T ++ AA       +G S ++DP GV +    E   + +A +  
Sbjct: 186 KEYHWRTLLTARAIENTIFVAAADHAPPIGVGHSMVVDPMGVELVTIGERTDVAVAHIEH 245

Query: 239 ERVRQVRAQLPVLNNRRFAP 258
            R+ +VRA  P L  RR+  
Sbjct: 246 SRLDEVRAINPALELRRYGV 265


>UniRef50_C0GEE7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Dethiobacter alkaliphilus AHT 1
           RepID=C0GEE7_9FIRM
          Length = 261

 Score =  280 bits (717), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 65/263 (24%), Positives = 116/263 (44%), Gaps = 14/263 (5%)

Query: 1   MLVAAGQFAVTS--VWEKNAEICASLMAQAAENDA--SLFALPEALLARDDHDADLSVKS 56
           M VA  Q  V+     E+  +    +M +    +    L  LPE   +            
Sbjct: 1   MNVAIIQLEVSDVHSREERFKKVEQIMLELHAGNPQPDLILLPEIWGSGF-FRFQDYAAH 59

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD 115
           ++  EGE    L   +++     +    V       +N  + +   G ++++Y K+HL+ 
Sbjct: 60  SEEAEGETYSFLAPWAEKMNCHILGGSIVERDGNHLYNTALFIDPHGKLISKYRKIHLFG 119

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
             + +ES+ +  G     +++ +    G+ TCYDLRFPEL    A  GA+  ++ +AW  
Sbjct: 120 YKS-EESKLLTRGTTP-TVIKTDLGTFGISTCYDLRFPELYRKMADLGAQAFLVTSAWPL 177

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPAL 231
              +  HW+     RAL+  CY+++    G    N   G S ++DP+G  + +A E PAL
Sbjct: 178 A--RLEHWTLFNRTRALENQCYLISCNCSGQIKENPFAGNSMMVDPWGTVLHSAGEEPAL 235

Query: 232 IMAEVTPERVRQVRAQLPVLNNR 254
           +   +    V ++R   P  N+R
Sbjct: 236 LHGSIDLSHVSEIRDSFPAFNDR 258


>UniRef50_Q23ND3 Hydrolase, carbon-nitrogen family protein n=1 Tax=Tetrahymena
           thermophila SB210 RepID=Q23ND3_TETTH
          Length = 284

 Score =  279 bits (716), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 81/275 (29%), Positives = 128/275 (46%), Gaps = 18/275 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           V   Q   T   ++N E     + QA E  A +   PEA           + ++A+ ++G
Sbjct: 9   VGVVQMCSTHNKKQNMEFILQNLKQAHEKQAKICFFPEAFA-MISRSFAETFENAEYIDG 67

Query: 63  EFLGRLRRESKRNMMTTILTIHVPS---TPGRAWNMLVALQA-GNIVARYAKLHLYDAF- 117
           E +  LR  +K+  +   L            +  N  + +   GNIV  Y KLHL+D   
Sbjct: 68  EMINCLRDHAKKYNLWLSLGGFQERLKENDKKMGNTHIIIDNLGNIVQTYKKLHLFDISI 127

Query: 118 ----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA-LQGAEILVLPAA 172
                I ES     G+++  +++    ++GL  CYDLRFPEL    A  Q AEIL++P+A
Sbjct: 128 DTKNTISESSGYVFGDQVPNVVDSPAGRLGLSICYDLRFPELFRLLAVQQKAEILLVPSA 187

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +      + HW TLL ARA++  C+++AA + G  N      G S +IDP+G  +     
Sbjct: 188 F-FKKTGQAHWHTLLKARAIENQCFVIAAAQAGQHNDKRESYGHSLVIDPWGEVLLDMGP 246

Query: 228 MP-ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
               +   E+  E++  VR  LP +N+ R    +L
Sbjct: 247 EKLGIDFVEIDLEKIDTVRKGLPAINHIRNDIYKL 281


>UniRef50_C7CES6 Putative N-carbamyl-D-amino acid amidohydrolase n=1
           Tax=Methylobacterium extorquens DM4 RepID=C7CES6_METED
          Length = 300

 Score =  279 bits (716), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 66/276 (23%), Positives = 110/276 (39%), Gaps = 21/276 (7%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD-ADLSVKSAQ 58
           + VA  Q A      + N      L+ QAA++ ASL  LPE        +  + ++  A+
Sbjct: 18  ITVACIQMAPRFGDTDANVARSLDLIGQAADDGASLVVLPELTNTGYVFETREEALALAE 77

Query: 59  L-LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
              +G       + +    +  +  +         +N  V +     +  Y K+HL+D  
Sbjct: 78  TVPDGPTCRAWAKIAAERSLHIVAGMTEREGSS-LYNSAVVIGPEGYIGTYRKMHLWDY- 135

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E+   + GN+  P+ E     +G+  CYD  FPE     ALQGA+I+ +P  WV  P
Sbjct: 136 ---ENLYFEPGNKGLPVFETALGAIGVAICYDGWFPETYRLLALQGADIVCVPTNWVPIP 192

Query: 178 ----LKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIA--AASE 227
                +E   + L  A A   + ++  A   G +     +GQS I+   G   A  A+  
Sbjct: 193 GQVAGREAMANILAMAAAHTNSLFIACADRVGTERGQAFLGQSLIVSHTGWPAAGPASRT 252

Query: 228 MPALIMAEVTPERVRQVRAQLPV---LNNRRFAPPQ 260
              ++ AE+     R+ R        L +RR     
Sbjct: 253 DEDIVSAEIDLGAARRARRWNSFNEVLRDRRTDVYG 288


>UniRef50_C1SI84 Predicted amidohydrolase n=1 Tax=Denitrovibrio acetiphilus DSM
           12809 RepID=C1SI84_9BACT
          Length = 259

 Score =  279 bits (716), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 86/259 (33%), Positives = 128/259 (49%), Gaps = 3/259 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M  AA Q  ++ + E+N E     + +A++    L  LPE ++       +L   +  + 
Sbjct: 1   MRAAAVQINLSGIKEQNLEKSLMYIKKASD--CDLVVLPEMVMGNRGDGVELYQLAEDVE 58

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
            G F   LR  + R  +     +   +   + +N  V     G+I A+Y KLHL+DA + 
Sbjct: 59  TGSFASSLRNAAVRYQVDVCACLWEETGTEKVYNTAVVYGSDGSIKAKYRKLHLFDALSF 118

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            ES  +  G+E  P+ E  G+K GL  CYDLRFPE   +   +GAE+ ++PAAW  G LK
Sbjct: 119 TESDYMLRGSERPPVFESGGIKCGLSICYDLRFPETYRSLVKRGAELFIVPAAWYGGELK 178

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
             H  TLL  RAL+ TCY + A  CG    G S    PF    +A      L++ EV  +
Sbjct: 179 IEHLHTLLRTRALENTCYALTANLCGGNFSGYSVSFGPFAEECSALQNDEGLLVIEVDKK 238

Query: 240 RVRQVRAQLPVLNNRRFAP 258
            + +VR++LP L N R   
Sbjct: 239 HLSEVRSKLPCLENFRNDI 257


>UniRef50_A1WYY7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Proteobacteria RepID=A1WYY7_HALHL
          Length = 286

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 78/268 (29%), Positives = 122/268 (45%), Gaps = 15/268 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VAA Q A     E N +    L+ +AA   A L  LPE        D D    +    +
Sbjct: 21  RVAAVQMASGPHVEANLQEAERLIGEAAAAGAELVVLPENFAIMGYQDTDKLKYAEPDGD 80

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNML-VALQAGNIVARYAKLHLYD--- 115
           G     L  +++R+ +  +         G  R      V    G  +A Y K+HL+D   
Sbjct: 81  GPIQAFLAEQARRHRIVLVGGTIPLQGEGPERVRPTAPVYGPDGGRLACYDKIHLFDVEV 140

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               A +ES     G     +++    ++G+  CYDLRFPEL    A QGAEI+ +P+A+
Sbjct: 141 APGEAYRESNTQQPGATPL-VVDTPVGRLGVAVCYDLRFPELFRELADQGAEIVAVPSAF 199

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAASEM 228
                 E HWS L+ ARA++   YMVA  +      G +  G+S ++DP+G  + +    
Sbjct: 200 TA-VTGEAHWSILVRARAIENLFYMVAPNQGGYHVNGRETHGESMVVDPWGRVMKSLERG 258

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
             +I  EV+  R+ ++R + P L +R+ 
Sbjct: 259 AGVITVEVSLSRLHEIRERFPALLHRKL 286


>UniRef50_Q9LE50 Nitrilase 1 like protein n=2 Tax=Viridiplantae RepID=Q9LE50_ARATH
          Length = 316

 Score =  278 bits (712), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 71/265 (26%), Positives = 123/265 (46%), Gaps = 18/265 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q    +    N   C+ L+ +AA   A L   PE      D + +   K A+ L
Sbjct: 37  VRVAAAQMTSVNDLMTNFATCSRLVQEAALAGAKLICFPENFSFVGDKEGESV-KIAEPL 95

Query: 61  EGEFLGRLRRESKRNMMTT-ILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD--- 115
           +G  + R    ++ + +   +             N  V +   G I   Y K+HL+D   
Sbjct: 96  DGPVMERYCSLARDSNIWLSLGGFQERFDDTHLCNTHVVIDDAGMIRDTYQKMHLFDVDV 155

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA-LQGAEILVLPAA 172
               + +ES     G +I  + +    ++GL  CYDLRFP++       Q A++L++P+A
Sbjct: 156 PGGSSYKESSFTVPGTKIVSV-DSPVGRLGLTVCYDLRFPKIYQQLRFEQKAQVLLVPSA 214

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW  LL ARA++T CY++AA + G  N      G + IIDP+G  +    +
Sbjct: 215 FTK-VTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDTLIIDPWGTVVGRLPD 273

Query: 228 M--PALIMAEVTPERVRQVRAQLPV 250
                +++A++    +  VR ++P+
Sbjct: 274 RVSTGIVVADIDFSLIDSVRTKMPI 298


>UniRef50_Q2JDM2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=43 Tax=cellular organisms RepID=Q2JDM2_FRASC
          Length = 404

 Score =  278 bits (712), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 80/265 (30%), Positives = 120/265 (45%), Gaps = 14/265 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAE-ICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           +  A  Q       E+NA      ++ +  +  A L  LPE  +    H  D     A+ 
Sbjct: 5   VRAAVLQLGCPD--EENAADRVRRVLGEIRQTQADLVVLPELWVTGYFH-FDRYEAEAEA 61

Query: 60  LEGEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLVALQAGNIV-ARYAKLHLYDAF 117
           L G  +  LR  ++      +       S  GR +N  V +    ++   Y K+HL+   
Sbjct: 62  LTGPTVTALREAARERGCHLVAGSIVERSADGRLFNTTVLIGPDGMIRHAYRKVHLFGYG 121

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
           +  E+R +  G  +  +   E   VGL TCYDLRFPEL    A  GAEI+V+ +AW    
Sbjct: 122 SA-EARLLTPGATVGTV-PTELGIVGLATCYDLRFPELFRLLAEGGAEIVVVVSAWPLA- 178

Query: 178 LKEHHWSTLLAARALDTTCYMVAAG----ECGNKNIGQSRIIDPFGVTIAAASEMPALIM 233
            +  HW  L   RA++   Y+VA      + G +  G S ++DP+G  +A A   P  + 
Sbjct: 179 -RLDHWRVLTRTRAIENQVYLVACNAAGRQAGREMAGASVVVDPWGEVLAEAGPRPTTVR 237

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAP 258
           AE+ P R   VRA+ PVL +RR   
Sbjct: 238 AELDPSRPAAVRAEFPVLTHRRLGV 262


>UniRef50_B6HUF1 Pc22g05380 protein n=28 Tax=Leotiomyceta RepID=B6HUF1_PENCW
          Length = 274

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 80/273 (29%), Positives = 131/273 (47%), Gaps = 17/273 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +L A GQ   TS    N   C  L+ +AA   A +  LPEA              +    
Sbjct: 2   VLAAVGQLCSTSNITSNLAQCKVLVRKAAAAGAKVLFLPEASDYIASSAEQSYSLAGSEE 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVA-RYAKLHLYD---- 115
              F+  L+R++    +   + IH  ++  R  N+L+ +    I+  +Y K+H++D    
Sbjct: 62  RTSFVSSLQRDALEQNIHINVGIHEVASETRLKNLLIWIDDKGIITQKYQKIHMFDVDIK 121

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               ++ES  V  G +I    E    +VGL  C+DLRFPE+ LA   + AEI+  P+A+ 
Sbjct: 122 DGPVLKESASVQPGQQIPTPFETPIGRVGLSICFDLRFPEIGLALRRKDAEIITYPSAFT 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE-- 227
             P  + HW  LL ARA++T  Y++AA + G  N      G S I++P+G  +A   +  
Sbjct: 182 V-PTGKAHWEPLLRARAIETQSYVIAAAQAGPHNEKRRSYGHSIIVNPWGEVVAKLGDEH 240

Query: 228 -MPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             P +  A++  + V ++R ++P+L  RR    
Sbjct: 241 QEPQIATADIDLDLVAKIRREMPLL--RRNDLY 271


>UniRef50_Q0S3S2 Possible amidohydrolase, carbon-nitrogen hydrolase family protein
           n=11 Tax=Actinomycetales RepID=Q0S3S2_RHOSR
          Length = 265

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 101/262 (38%), Positives = 143/262 (54%), Gaps = 3/262 (1%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  QFA     ++N     +L A+AA   A +   PE  +       +  V+SA+ L+G
Sbjct: 4   VAVIQFAPGQDKQENLRTLRTLAAEAAGRGAKVVVAPEYAMFTAPRTDERIVESAEGLDG 63

Query: 63  EFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNMLVALQAGN-IVARYAKLHLYDAFAIQ 120
           EF+  L   +K   +  +  ++          N +VAL  G  IVA Y KLHLYDAF  +
Sbjct: 64  EFVSGLAATAKELDVHLVAGVNEHLPGDDHISNTIVALGPGGDIVATYRKLHLYDAFGYK 123

Query: 121 ESRRVDAGN-EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           ES  + AG  +      V+G+  G+ TCYDLRFPE+       GA++L+LPA WV GPLK
Sbjct: 124 ESDVIRAGEIDAPQTFAVDGLTFGMQTCYDLRFPEVTRRIVDAGADVLLLPAQWVPGPLK 183

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
           E HWSTL+ ARA++ T Y+ AA +      G S I+DP GVT+A+  E     +A V+ E
Sbjct: 184 EDHWSTLVRARAIENTVYVAAADQSARTGAGNSMIVDPMGVTLASLGERVGTAVAAVSAE 243

Query: 240 RVRQVRAQLPVLNNRRFAPPQL 261
           R+ +VR + P L  RRF   ++
Sbjct: 244 RITEVREKNPALALRRFTVSEI 265


>UniRef50_Q3SLE9 Carbon-nitrogen hydrolase n=101 Tax=Proteobacteria
           RepID=Q3SLE9_THIDA
          Length = 319

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 70/266 (26%), Positives = 118/266 (44%), Gaps = 16/266 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q A       N      L+  A +  A L  LPE        D+ +        
Sbjct: 29  VRVAAIQMASGPSVPANLAEAERLIELAVQAGARLVVLPEFFCIMAMKDSYVVKAREAEG 88

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPST--PGRAWNMLVALQ-AGNIVARYAKLHLYDA- 116
           +G     L R +K++ +  I          P +  N  +     G  +ARY K+HL+   
Sbjct: 89  DGPIQTFLARMAKKHKVWLIGGSVPLEASVPNKVRNSCLVYDERGKQIARYDKIHLFGLD 148

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 QE++ ++ G++   ++     ++GL  CYDLRFPEL    A+   +I+V+P+A+
Sbjct: 149 LGNERYQEAKLIEPGDK-VVVVNSPFGRIGLSVCYDLRFPELYR--AMPDVDIIVVPSAF 205

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGE-----CGNKNIGQSRIIDPFGVTIAAASEM 228
                   H+ TL+ ARA++   Y++A  +      G +  G S I+DP+GV +      
Sbjct: 206 TA-TTGRAHFETLVRARAIENLAYVIAPAQGGYHLSGRETHGDSMIVDPWGVVLDRLPRG 264

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNR 254
             +++A + P     +R  LP L +R
Sbjct: 265 SGVVIANINPAYQASLRKSLPALQHR 290


>UniRef50_C6N396 Nitrilase n=2 Tax=Legionella RepID=C6N396_9GAMM
          Length = 286

 Score =  277 bits (710), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 70/265 (26%), Positives = 125/265 (47%), Gaps = 14/265 (5%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  Q   ++   +N +    LM QA E+DA L  LPE       H+ D         +
Sbjct: 17  RVALAQMVSSANVVENLQQVEKLMIQAREDDAQLVLLPENFAFMGRHETDKLHIGEVYGQ 76

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVALQAGNI-VARYAKLHLYDA--- 116
           G    ++ + +K+  +  +         G +     +      +  ARY K+HL+D    
Sbjct: 77  GPIQEKISQLAKQLGLWVVAGTMPLKGSGSKVRASCLVYDEQGLCAARYDKIHLFDVSVS 136

Query: 117 --FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              A  ES  ++ G+++  +++    K+GL  CYDLRFPEL     +QGA++  +P+A+ 
Sbjct: 137 PQEAYCESATIERGHDLV-VVDTPVGKIGLTVCYDLRFPELYQQLLIQGAQLFTVPSAFT 195

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                  HW  LL ARA++   Y++AA + G+        G S II+P+G  +A  ++  
Sbjct: 196 A-VTGLAHWEVLLRARAIENLSYVLAANQGGHHENGRSTYGHSMIIEPWGAVLAQQADGI 254

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNR 254
            ++ AE+  + ++ +R   P +++ 
Sbjct: 255 GVVTAEIDLQGLQHLRKTFPSVDHH 279


>UniRef50_A8IKB0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=13 Tax=cellular organisms RepID=A8IKB0_AZOC5
          Length = 584

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 61/268 (22%), Positives = 104/268 (38%), Gaps = 17/268 (6%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDD-HDADLSVKSAQ 58
           + VA  QF  T    E+N     +L  QAA   A L   PE         D        +
Sbjct: 5   ITVATVQFEPTLFEKERNITRLLALCEQAARAGAKLIVTPEMGTTGYCWFDRAEVAGQVE 64

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
            + G    R    ++ +    ++ +         +N  V +    +V  + K H Y    
Sbjct: 65  SVPGPTTERFAALAREHGCWIVIGMPEVDADDIYFNSAVLIGPDGVVGTHRKSHPY---- 120

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           I E +   AG+    + E    ++GL+ C D+ F E A   A+QGA+++   + W+    
Sbjct: 121 ISEPKWSAAGDLGHQVFETPIGRIGLLICMDIHFIETARLMAVQGADVICHISNWLAERT 180

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
              +W     +RA +  CY++ A   G +      G S +I+P G  +A         +A
Sbjct: 181 PAPYW----ISRAFENGCYVIEANRWGLERTVQFSGGSCVIEPDGSIVAVIDSGDGFALA 236

Query: 235 EVTPERVRQVRAQL--PVLNNRRFAPPQ 260
           ++   +  + R  L  PV   RR    +
Sbjct: 237 QMDLAK-ARARTVLGEPVFTQRRPELYR 263



 Score =  182 bits (463), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 55/266 (20%), Positives = 87/266 (32%), Gaps = 36/266 (13%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQLL 60
            VA  QFA       N     +   QA  E  A L   PE  L+     A      A   
Sbjct: 293 RVAVAQFAPGEGIADNLSRICAFAVQARTEEGADLVVFPELALSGLSDPAVR----ALSS 348

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +     RL   S R  +  ++     +  G  +N    L    +VA + KLHL       
Sbjct: 349 DDPAFMRLLNLSARLGLHMVVGFAERAADG-LYNSAALLGPEGLVAIHRKLHL----NAA 403

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA-------- 172
           +      G +   + +    ++GL+  +D  F E     AL+G +++  PAA        
Sbjct: 404 DRPWATPGAD-WTVADTSLGRIGLLIGHDATFCESGRILALRGCDLIACPAAIAGRFSYG 462

Query: 173 ---------WVRGPL-KEHHWSTLLAARALDTTCYMVAAGECGNK--NIGQSRIIDPFG- 219
                    W        HHW      RA +   ++  A     +   +G S +  P   
Sbjct: 463 HGGSRVAQNWPIPTGADPHHWHHF-RVRAGENNVFLAFANVHAPEAGFMGLSGVFGPDTF 521

Query: 220 ---VTIAAASEMPALIMAEVTPERVR 242
               + A   E   L +A +    + 
Sbjct: 522 AFPRSEALLPEGEGLAVAIMDTSNLD 547


>UniRef50_Q1AWK1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Bacteria RepID=Q1AWK1_RUBXD
          Length = 276

 Score =  276 bits (708), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 78/270 (28%), Positives = 127/270 (47%), Gaps = 16/270 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
            AA Q + T    +N  +  +L+ +AA   A+L ALPE          ++  ++A+ + G
Sbjct: 8   AAAIQMSSTPDRGENRRVAEALIREAAAAGATLVALPELWSCHGL--EEVYRENAEPIPG 65

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNML-VALQAGNIVARYAKLHLYDAFA- 118
                L   ++   +  +    +    G  R  N   +    G++VA Y K+HL+D    
Sbjct: 66  PTTEFLGSLARELGIYLLGGSILERVSGSERLGNTSTLYAPDGSLVAVYRKVHLFDVEVS 125

Query: 119 ---IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
                ES  +  G E     +   + VGL  CYD+RFPEL    AL+GAE+L +PAA+  
Sbjct: 126 GRRYLESANIAPGGEAVA-AKAGPVTVGLSVCYDVRFPELYRLLALRGAEVLAVPAAFTL 184

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPA 230
              K  HW  LL ARA++   Y++A  + G K       G+S I+DP+G  ++   +   
Sbjct: 185 QTGK-DHWELLLRARAVENQAYVLAPAQWGRKADGRWTYGRSMIVDPWGTVLSTCPDRDG 243

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
             +A +    + ++RA+ P L NRR    +
Sbjct: 244 YALATLDLGYLERLRAEFPSLANRRPRVYR 273


>UniRef50_A7IJX5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=101 Tax=Alphaproteobacteria RepID=A7IJX5_XANP2
          Length = 310

 Score =  276 bits (708), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 83/271 (30%), Positives = 129/271 (47%), Gaps = 15/271 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A  Q         N +   +L+ +AA + A     PE     +   A L  K  +  
Sbjct: 25  LRIALVQLRSGRDPAANLDATVALVREAARDGARYVQTPEVTNLMELDRAVLFEKLREEA 84

Query: 61  EGEFLGRLRRESKRNMMTTILTI-HVPSTPGRAWNMLV-ALQAGNIVARYAKLHLYD--- 115
           +   L  LR+ ++   +   +    +  +  +A N        G I+ARY K+H++D   
Sbjct: 85  DDATLKALRQLAQELGIFLHIGSLALKVSDKKAVNRAFMVGPDGEIIARYDKIHMFDVDL 144

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES     G E A L  V   + GL  CYDLRFP L  A A  GA++L +P+A+
Sbjct: 145 GNGESYRESSAYRPG-ERAILANVGAFRFGLTICYDLRFPSLYRALAEGGAQVLTVPSAF 203

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAASEM 228
            R P  E HW  LL ARA++   Y++AA +      G +  G S ++DP+G  IA     
Sbjct: 204 TR-PTGEAHWHVLLRARAIENGAYVLAAAQGGKHENGRETFGHSLVVDPWGRVIAEGGAD 262

Query: 229 PALIMAEVTPERVRQVRAQLPVLNN-RRFAP 258
           P +I+AE+  + V   RA++P L+N RRF  
Sbjct: 263 PGVILAEIDLKEVAAARARIPSLSNGRRFEI 293


>UniRef50_Q0S9Y1 Possible nitrilase n=3 Tax=Actinomycetales RepID=Q0S9Y1_RHOSR
          Length = 270

 Score =  276 bits (707), Expect = 5e-73,   Method: Composition-based stats.
 Identities = 76/270 (28%), Positives = 118/270 (43%), Gaps = 15/270 (5%)

Query: 1   MLVAAGQFAVTSV--WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M +A  Q A           E   +L+   AE    L  LPE      +H  D    +A+
Sbjct: 1   MKIALAQLASPDSETPAHRLERVRNLLTGLAER-VDLIVLPELWRVGYNH-FDDYSTAAE 58

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDA 116
            L G  +  L   +                  GR  N  V +   G I   Y+K+H++  
Sbjct: 59  TLGGGTVQVLAAVAVERQCYIHAGSIVEQGEEGRLRNTAVLIGPDGQIHHHYSKVHVFGY 118

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
            ++ E++ +  G +I    +     +   TCYDLRFP L       GA+++++PAAW + 
Sbjct: 119 DSL-EAQLLQPGTQIHTT-DTPFGPIAATTCYDLRFPGLWTELVAAGAQLVIVPAAWPKA 176

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALI 232
             ++ HW  L +ARA+D   +++A    G  N     G SRI+DP+G  IA A     + 
Sbjct: 177 --RKEHWRLLTSARAVDNQVFVIACNATGTHNSVELGGHSRIVDPWGTVIAEADSSEGIT 234

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           +AE+ P  V + RA+ PVL + R      L
Sbjct: 235 IAEIDPAVVDRTRAEFPVLRD-RLDDYSFL 263


>UniRef50_A9B254 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B254_HERA2
          Length = 259

 Score =  276 bits (706), Expect = 7e-73,   Method: Composition-based stats.
 Identities = 70/265 (26%), Positives = 110/265 (41%), Gaps = 14/265 (5%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + VA  Q   V    E N      L A+A    A+L  LPE          + + + +  
Sbjct: 3   LTVALAQIDLVLGDREANLATVRQLAARAEMAGAALLVLPELWGTGYLL--EQAHELSDP 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYDAFA 118
           L       +   + R+ +  + ++       + +N   +    G  +  Y K HL     
Sbjct: 61  LGKGLFEEVAVLAARHHLAIVGSLLERDGE-QVYNTATLYDAQGKRLHSYRKTHL--IGL 117

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           +QE R + AG +   + E          CYDLRFPEL    AL GA ++++PA W     
Sbjct: 118 MQEDRYLAAGQQA-EVFETAWGTSACAICYDLRFPELFRRYALAGAGVIIIPAEWP--TA 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMA 234
           +  HW TLL ARA++    ++A    G    N+  G S +IDP+G  +    +   L+ A
Sbjct: 175 RIEHWRTLLRARAIENQAVVIACNRVGSDRANQFGGHSVVIDPWGKVLVEGDDQAGLLTA 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
            V    + + R  LPV  +RR    
Sbjct: 235 TVDLASIAKARDFLPVFRDRRVELY 259


>UniRef50_C9KQR5 Hydrolase, carbon-nitrogen family n=1 Tax=Mitsuokella multacida DSM
           20544 RepID=C9KQR5_9FIRM
          Length = 259

 Score =  276 bits (706), Expect = 7e-73,   Method: Composition-based stats.
 Identities = 71/266 (26%), Positives = 112/266 (42%), Gaps = 14/266 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M ++  Q  V  +  + N +    ++A+A   +  +  LPE                   
Sbjct: 1   MKISILQMPVAFARPDDNIKTLRRMVAEAMRAEPDVLVLPELWRLGFYPQPIAVHADLDG 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            +   +  L   ++ N +  +         G+ +N        G  VA Y K HL+    
Sbjct: 61  QQSRTV--LAELARTNGVNIVGGTVANRREGKVYNTCYVFDRTGTEVASYDKTHLFSPSG 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             ES+   AG E+     ++G++ G+  CYD+RFPE     AL+   +L LPAAW    L
Sbjct: 119 --ESKDFAAGREMVT-FRLDGVRCGVAVCYDVRFPEFIRKLALEDIAVLFLPAAWPASRL 175

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN-----KNIGQSRIIDPFGVTIAAASEMPALIM 233
              HW  L  ARA++   Y++AA E G         G S I+DP+G  I  A E  A++ 
Sbjct: 176 S--HWQILTRARAIENQFYVIAANEAGTDEQGNHLAGHSAILDPWGEAIVEAGESEAILT 233

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAPP 259
           A + P   R +R  + V  +RR    
Sbjct: 234 ARLRPGLRRHIRETINVFADRRPELY 259


>UniRef50_C7TF35 Hydrolase, carbon-nitrogen family n=17 Tax=Lactobacillales
           RepID=C7TF35_LACRL
          Length = 260

 Score =  275 bits (705), Expect = 9e-73,   Method: Composition-based stats.
 Identities = 68/265 (25%), Positives = 116/265 (43%), Gaps = 14/265 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  +     EKN +  A+ +A+AA+  A +  LPE        D +    +A  
Sbjct: 4   LTIALAQIDIAFGQPEKNFQTVANAVAEAAQQGAEVVVLPEMWNTGY--DLEHLTTTANP 61

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLV-ALQAGNIVARYAKLHLYDAFA 118
                   L   +++  +  +      +  G  +N  +   Q G  +A+Y K+H +    
Sbjct: 62  DGLRTKAFLSALAQQYHLAIVGGSVAAAENGHFYNRSLTVDQRGRQLAKYDKVHRFRL-- 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E + + AG          G+   +  CYDLRFPE     A  G ++  LPA W     
Sbjct: 120 MNEEKFITAGATADHF--TLGVPASVAICYDLRFPEWFRRMASDGTQLFFLPAEWPTP-- 175

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
           +   ++ LLAARA++   Y+VA    GN       GQS+++DPFG  +    + P + + 
Sbjct: 176 RLPQFNALLAARAIENQAYVVAVNRVGNDPNNAFGGQSQVVDPFGERLLKLDDQPQVRIV 235

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
            +  +R+   R Q+PV  +RR    
Sbjct: 236 TIDLDRIAAARQQIPVFTDRRPELY 260


>UniRef50_Q02J62 Putative N-carbamoylputrescine amidohydrolase n=4 Tax=Bacteria
           RepID=Q02J62_PSEAB
          Length = 303

 Score =  275 bits (705), Expect = 9e-73,   Method: Composition-based stats.
 Identities = 64/280 (22%), Positives = 108/280 (38%), Gaps = 20/280 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
           + +A  QFA +   + N +    L+ +AA   A L  L E               ++ A+
Sbjct: 4   LTLATTQFACSWSLDDNLDRAERLVREAAARGAQLVLLQELFATPYFCIEQDHRHLRLAE 63

Query: 59  LLEG-EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
              G   L R    ++   +   L+ +  +   R  ++ VA   G ++  Y K H+ +A 
Sbjct: 64  TFRGSRVLARFSSLARELGVVLPLSWYERAGNARFNSLAVADADGRLLGVYRKAHVPNAI 123

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
             QE      G+    + +    ++G+  C+D  FPE A   AL GAE+L+ P A    P
Sbjct: 124 GYQEKEYFSPGDSGFRVWDTAVGRIGVGICWDQWFPETARCLALLGAEVLLFPTAIGSEP 183

Query: 178 L-----KEHHWSTLLAARALDTTCYMVAAGECGNK-----------NIGQSRIIDPFGVT 221
                    HW      +A      +VAA   G +             G S I D  G  
Sbjct: 184 GAAQLDSRDHWQIAQRGQAAANLVPLVAANRIGREVACGDPALAMRFYGSSFIADHKGAL 243

Query: 222 IAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           +AAA  +  A+++  +  + + + R    V  +RR     
Sbjct: 244 LAAAGRDEEAVLVCGLDLDAIGEERLAWGVYRDRRPELYG 283


>UniRef50_A0BR54 Chromosome undetermined scaffold_122, whole genome shotgun sequence
           n=2 Tax=Oligohymenophorea RepID=A0BR54_PARTE
          Length = 281

 Score =  274 bits (703), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 74/279 (26%), Positives = 119/279 (42%), Gaps = 22/279 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +A  Q A+T+   +   +    + +AA   + +  L E   +           +A+  
Sbjct: 5   FKIACIQNAITATKTQTLALVKDQIKEAAIQGSKVCILGECFNSYYV--KAQLQNNAEDF 62

Query: 61  --EGE--FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYD- 115
              GE   L  +   SK+  +  I +I   S   + +N       G ++  Y K HL+D 
Sbjct: 63  GKTGERQTLDLISEISKQFGIMIIGSIPEKSGD-KMYNTAFCFNNGQLLVTYRKTHLFDI 121

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES    AG+    +++ E  K G+  CYD+RFPELA     +G   LV P 
Sbjct: 122 DIPGKITYKESLTFSAGDN-YKIVDTEYGKFGIGICYDIRFPELAQIMREKGCHFLVYPG 180

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC---GNK-----NIGQSRIIDPFGVTIA 223
           ++        HW  LL ARA+D  CY+         GN        G S ++DP    +A
Sbjct: 181 SFNL-TTGPLHWELLLKARAVDYQCYVAGVSSARYMGNDESIYKAWGHSTLLDPMAKVLA 239

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
                P++I++EV  + + QVR Q+PV   RR    +L+
Sbjct: 240 TCEHDPSVIISEVDLDYLEQVRQQIPVSQQRRNDIYELI 278


>UniRef50_Q2N7J4 Hydrolase n=5 Tax=Sphingomonadales RepID=Q2N7J4_ERYLH
          Length = 283

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 58/275 (21%), Positives = 104/275 (37%), Gaps = 16/275 (5%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSA-- 57
           + VAA Q  + +   + N +  A L+ QAA   A +   PE          +     A  
Sbjct: 4   ITVAALQLPLGSEDEQANIDAVAELVEQAAARGAEIVLPPELFSGPYFCQVEDEALFALA 63

Query: 58  -QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD 115
              LE   +  +R+ + +  +    +          +N L  +   G +   Y K H+ D
Sbjct: 64  RPTLEHPSVVAMRKLAGKLEIAIPTSFFER-DGHHYYNTLAMIGPDGELQGTYRKSHIPD 122

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +E      GN+   + +V G ++G+  C+D  +PE A   AL GAE+L  P A   
Sbjct: 123 GPGYEEKFYFRPGNDGFKVWDVCGTRIGVGVCWDQWYPECARVMALMGAELLFYPTAIGS 182

Query: 176 GPLKEH-----HWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAAS 226
            P          W   +   ++     ++AA   G +      G S I + +G  I    
Sbjct: 183 EPYDADFDTSRMWQRSMQGHSVSNCMPVIAANRIGTEGEAKFYGHSFITNEWGDKIVEFG 242

Query: 227 EMP-ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
                +++A +  +   + RA +    +RR    +
Sbjct: 243 AEEDGVLVATLDLDEAAKHRAGMGFFRDRRPQLYR 277


>UniRef50_A4S5E0 Predicted protein n=2 Tax=Ostreococcus RepID=A4S5E0_OSTLU
          Length = 282

 Score =  274 bits (701), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 74/276 (26%), Positives = 120/276 (43%), Gaps = 28/276 (10%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            +A  Q   T+ ++ N +    L  +A         LPEA       DA      A+ L+
Sbjct: 7   RIACAQMTSTADFQHNLQTVTELCKRAKAEACEALFLPEAFARIGATDAS----YAEPLD 62

Query: 62  GEFLGRLRRESKRNMMTT-ILTIHVPSTPGR-AWNMLVALQA--GNIVA-RYAKLHLYD- 115
           G  +      +K   +   +         GR  +N  V +    G I    Y K+HL+D 
Sbjct: 63  GPIVRACCALAKEYGLWMSLGGYAERDGDGRKRFNSHVMIDPRSGEISGDVYRKIHLFDT 122

Query: 116 -------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA-LQGAEIL 167
                     ++ES    AG  +A   +    KVG   CYDLRFP++  A      A+++
Sbjct: 123 DAAVGVDGGGMRESDYTRAGTTLAS-YDTTFGKVGASICYDLRFPDVYQALRFEHEADVI 181

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTI 222
            +P+A+ +    + HW  LL ARA++T CY+VAA + G         G + +IDP+G  +
Sbjct: 182 CVPSAFTKST-GQAHWEVLLRARAIETQCYVVAAAQAGKHGETRESYGHAMVIDPWGRIV 240

Query: 223 AAASE---MPALIMAEVTPERVRQVRAQLPVLNNRR 255
           A   +      + +AE+    V  +R Q+P+  +RR
Sbjct: 241 AKMDDPSNEVGIAVAEIDLALVDSIRTQMPLAEHRR 276


>UniRef50_Q65KK0 Methylthioribose recycling protein n=1 Tax=Bacillus licheniformis
           ATCC 14580 RepID=Q65KK0_BACLD
          Length = 259

 Score =  274 bits (701), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 68/265 (25%), Positives = 112/265 (42%), Gaps = 14/265 (5%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + ++  QF +      +N +    L+ Q     A +  LPE        D       A  
Sbjct: 3   LTISCLQFDIAYGNPSENFKKAEQLIEQ-ESRKADILLLPELWTTGY--DLKNLGSIADE 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
              +    L+  +K N +  +            +N++      G+++  Y+K HL+    
Sbjct: 60  EGRQTKRWLQETAKANRIHIVCGSVAVKKKSGVYNIMYIADKNGHLIKEYSKAHLFQL-- 117

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E   + AG+      E+EGM      CYD+RFPE       +GA I+ + A W     
Sbjct: 118 MDEHLYLSAGSGDGR-FELEGMPAAGFICYDIRFPEWIRKHTSEGAGIIFVSAEWPLA-- 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALIMA 234
           +  HW +LL ARA++  C++ A    G    N+  G S +IDP G T+A A    A+I A
Sbjct: 175 RLDHWQSLLKARAIENQCFVAACNRSGKDPANEFAGHSTVIDPLGRTLAEAGRGEAVIRA 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
           E+    + + R Q+PV  + R    
Sbjct: 235 EIDLRDIEKARGQIPVFEDIRKDLY 259


>UniRef50_C1N8C1 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1N8C1_9CHLO
          Length = 361

 Score =  274 bits (701), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 66/300 (22%), Positives = 114/300 (38%), Gaps = 43/300 (14%)

Query: 1   MLVAAGQF-AVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + VA  Q    T+    N       +  AAE  A+L  LPE       +  +     A+ 
Sbjct: 56  VKVALCQLACPTADKVANIARAREAIRNAAEGGAALVVLPEMWNCPYAN--ESFPAHAET 113

Query: 60  LEG----EFLGRLRRESKRNMMTTILTIHVP-----------STPGRAWN-MLVALQAGN 103
           +        +  L   +  + +  +                       +N   V      
Sbjct: 114 IGANDPTPSVTMLSEAAAAHDIVLVGGSIPERGVGVGGGGGADEEDVLYNACCVFDGKRG 173

Query: 104 IVARYAKLHLYDA-----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALA 158
           ++AR+ K HL+D       + +ES  +  G E   +++    +VG+  C+D+RF E+A A
Sbjct: 174 LIARHRKTHLFDVDIPGEISFRESDTLTEG-EGLTVVDTAVGRVGVGICFDVRFGEMAAA 232

Query: 159 QALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTT-----------CYMVAAGEC--- 204
            A +GA++L+ P A+       HHW  L  ARA+D             C+++        
Sbjct: 233 MANRGADVLIYPGAFNT-VTGPHHWELLQRARAVDNQARSIHWSPYDRCFVLTCSPARNT 291

Query: 205 ---GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
              G +  G S  + PF   +A   E P ++ A++    V + R  +P+   RR     L
Sbjct: 292 TGEGYQAWGHSTAVGPFAEVLATTDERPGIVFADLDLGEVTRRRRNMPLATQRRGDLYAL 351


>UniRef50_A0LH50 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Syntrophobacter fumaroxidans MPOB
           RepID=A0LH50_SYNFM
          Length = 260

 Score =  274 bits (701), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 107/269 (39%), Gaps = 18/269 (6%)

Query: 1   ML---VAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKS 56
           M     A  Q  V     + N       + + A  +  L  LPE       +      + 
Sbjct: 1   MRELVAACLQLRVVPGNVDANLANAREGIEELASGECRLVVLPEMWACGFPYSR--LQEV 58

Query: 57  AQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYD 115
           A     E +  +R  ++R+ M  +      S  GR +N    +   G I   Y K+HL+ 
Sbjct: 59  ASRTP-EVVEEMRGWARRHGMVLV-GSLPESVDGRIYNTSYVIDANGEIAGSYRKVHLFS 116

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
                E      G     +   E  ++G+M CYDLRFPEL    AL GA I+ + + W  
Sbjct: 117 L--HHEDLHFGRGETSL-VCSTEAGELGVMICYDLRFPELGRKLALDGARIMCVSSHWPD 173

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPAL 231
             ++  HWS LL ARA++   +++    CG +      G S II P G  +  A   P  
Sbjct: 174 --IRIDHWSLLLRARAVENQLFVIGCNGCGTEKKMRYGGASAIISPMGKVLIEAGTGPES 231

Query: 232 IMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           I A +  E V + R  +    +R  A  +
Sbjct: 232 IAAALDMEEVDRFRKLITCFPDRVPAVYE 260


>UniRef50_D2RS34 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Haloterrigena turkmenica DSM 5511
           RepID=D2RS34_9EURY
          Length = 277

 Score =  274 bits (701), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 80/274 (29%), Positives = 125/274 (45%), Gaps = 23/274 (8%)

Query: 1   MLVAAGQFAVTSV-WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q  V     ++N E     +++AAE  A L ALPE          D   + A+ 
Sbjct: 9   LRLALAQLEVEPTAVDENVERALEAISRAAERGADLVALPELFNVGY-FAFDSYNRLAEP 67

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPS-----------TPGRAWNMLVALQAGNIVARY 108
           LEGE L RLR  +  + +  +    V               G A    +    G +   Y
Sbjct: 68  LEGETLTRLREAAADHEIAVLAGSIVEDLAATETADTPAEEGLANTAALFDADGGLQLVY 127

Query: 109 AKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
            K HL+   +  ES  +  G  I     V G+ VG  TCYDLRFPEL       GAE+++
Sbjct: 128 RKHHLFGYQSA-ESELLVPGERIET-ATVAGVPVGATTCYDLRFPELYRRLIDAGAELVL 185

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN------KNIGQSRIIDPFGVTI 222
           +P+AW     +  HW TL  ARA++   ++      G         +G+S + DP+G T+
Sbjct: 186 VPSAWPYP--RIEHWETLSRARAIENQAFVATINGSGRFPDEDATLLGRSTVYDPWGTTL 243

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           A++ + P L++A++    V ++R + P L +RR 
Sbjct: 244 ASSGDDPTLVVADLDLGAVDRIREEFPALRDRRL 277


>UniRef50_C5L8W7 Putative uncharacterized protein n=2 Tax=Perkinsus marinus ATCC
           50983 RepID=C5L8W7_9ALVE
          Length = 300

 Score =  273 bits (700), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 60/280 (21%), Positives = 100/280 (35%), Gaps = 22/280 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAE-NDASLFALPEALLARDDHDADLSVKSAQL 59
           + VA  Q  V      +       +  A + +   L  + E                   
Sbjct: 12  LRVAVLQTKVFPEKASSLRGARETLLAAIDISKPDLCVIGEMFTCPYHPKYFRQYGERLP 71

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQA-GNIVARYAKLHLYD-- 115
            +   L  ++  +K   +  I           + +N  + + + G +V  Y K HL+D  
Sbjct: 72  DQSPTLDMVKEVAKEKNVWIIGGTVPELDDADKVYNTALVVNSSGELVKTYRKAHLFDID 131

Query: 116 --------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI- 166
                        ES  +  GN    + +      GL  CYD+RFPE A        ++ 
Sbjct: 132 VPADGDKPGIRFFESETLSPGNSGPCVFDTPWGPFGLGICYDVRFPEYAALLRNIAPDLK 191

Query: 167 -LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN------IGQSRIIDPFG 219
            L+ P A+        HW  L  ARALDT CY+V A    ++N       G S +++P+G
Sbjct: 192 MLIYPGAFNM-TTGPAHWRLLGRARALDTQCYVVMASPSRSENPEDYQAWGHSMVVNPWG 250

Query: 220 VTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
             +    E       +V    V +VR  +P  + +R+   
Sbjct: 251 EVVDETDEKHGWFTVDVDLTMVDRVRRNIPTASQKRYDLY 290


>UniRef50_D1BL17 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Veillonellaceae RepID=D1BL17_VEIPT
          Length = 263

 Score =  272 bits (698), Expect = 7e-72,   Method: Composition-based stats.
 Identities = 57/266 (21%), Positives = 106/266 (39%), Gaps = 12/266 (4%)

Query: 2   LVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            ++  Q  V  +  E N      L++QA      +  LPE          D  +  +   
Sbjct: 4   RLSLIQMDVHVNEVEYNYARVQELLSQALSESPDIIVLPETWNTGFHPSKD-LINISDRN 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFAI 119
                  L   +K + +  +      +     +N   A  + G +V  Y+K+H +     
Sbjct: 63  GERTKALLSTFAKEHNVNIVGGSVAVAKEDLVFNTSYAYNRKGTLVGEYSKMHGFSPA-- 120

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +E +   +G       E++G+    + CYD+RFPEL    AL   E+L +PA W    L+
Sbjct: 121 KEDQYFASGTH-TTHFELDGIPCSTVICYDIRFPELVRMAALSNTELLFVPAQWPTMRLR 179

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMAE 235
             HW  L   RA++   ++ A   CG     ++ G S + DP+G  +        +   +
Sbjct: 180 --HWQVLNEVRAIENQLFLCAVNGCGTVGRVQSTGHSAVYDPWGTNLLEMDTREGISSID 237

Query: 236 VTPERVRQVRAQLPVLNNRRFAPPQL 261
           +    V  +R ++ +  +R+    +L
Sbjct: 238 IDLTVVEDIRNKINIFRDRKPELYKL 263


>UniRef50_D1NXA0 Hydrolase, carbon-nitrogen family n=8 Tax=Enterobacteriaceae
           RepID=D1NXA0_9ENTR
          Length = 277

 Score =  272 bits (696), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 18/273 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSA 57
           + VA  QF       ++N +  A L  QAA   A L   PE        D  ++     +
Sbjct: 6   VKVALAQFDSELGNKQRNLQRMAQLCEQAAAQGAKLICFPELATTGYRGDLLSNKLWDLS 65

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTP-GRAWNMLVALQAG--NIVARYAKLHLY 114
                E        + R  ++ +       +  G  +N +     G   I   + K+H +
Sbjct: 66  DSEGSETYCLFSELASRLNLSIVAGFAERGSYLGEVYNSVGLWNPGCKTISGVFRKVHAF 125

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                 E +    G+   P+ +    KVG+M CYD+ FPE+A    LQGAE+L+ P+AW 
Sbjct: 126 GI----EKQWFKNGDS-FPVFDTPIGKVGIMICYDMGFPEVARILTLQGAELLIAPSAW- 179

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAAS-EMP 229
                   W    A RAL+   +++A    G++      G S+++ P G  +  A+ +  
Sbjct: 180 -CVQDRDMWDINTACRALENGTHLLAVNRWGSEEDLHLFGGSKVLGPRGQVLCEATCDGE 238

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           AL++ EV        R  +P L +R+     LL
Sbjct: 239 ALLIGEVDFRLQAHTRLSVPYLRDRKPQRYGLL 271


>UniRef50_D1BX77 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Actinomycetales RepID=D1BX77_XYLCX
          Length = 298

 Score =  271 bits (695), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 93/262 (35%), Positives = 135/262 (51%), Gaps = 6/262 (2%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q  V +    N +   +++  AA   A L  LPE           +  + A+ L
Sbjct: 32  VRVAIAQIEVGADHAANRDAVTAVVRDAAARGADLVVLPEYAS--GFEPRGVGPEHAEPL 89

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
           +G F+  LR  ++ + +  +    +P   PGRA N +VA+   G +   Y K+HLYDAF 
Sbjct: 90  DGPFVSLLRALAREHGLAIVAGTTLPGEAPGRASNAIVAVGAQGELAGAYRKVHLYDAFG 149

Query: 119 IQESRRVDAG--NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
            +ES R++ G  +       V G+ VG++TCYDLRFPE A      GA+ ++ PAAWV G
Sbjct: 150 TRESDRLEPGPADAAPLTFAVGGLTVGVLTCYDLRFPEAARRVVDAGAQAILYPAAWVAG 209

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
           PLK  HW TLL ARA++ T  +V  G  G    G+S ++D  GV +    E P L +A +
Sbjct: 210 PLKADHWRTLLRARAIENTVAVVGVGMAGRTVTGRSLVVDADGVVVLELDETPQLAVATL 269

Query: 237 TPERVRQVRAQLPVLNNRRFAP 258
            P    + RA  P L NRR+  
Sbjct: 270 DPTATARTRAANPSLANRRYEV 291


>UniRef50_A1RZK0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RZK0_THEPD
          Length = 286

 Score =  271 bits (695), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 80/262 (30%), Positives = 129/262 (49%), Gaps = 7/262 (2%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLA--RDDHDADLSVKSAQ 58
           + VA  Q AV+    +N E    L+      DA L   PE L+         D   + A+
Sbjct: 16  VRVALHQLAVSGEKRENLEKALRLLEL---GDAYLHVFPEYLMGVDPGGPTRDYVWRVAE 72

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
            ++GEF  R+  ++    +  + T+ +   PG  +N  V  + G + A Y K+HL+DA+ 
Sbjct: 73  PIDGEFASRIVEKTGELGVAAVFTMFLREGPG-VYNAAVLAEEGKVKAVYRKIHLFDAYG 131

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +ES     G E   + +++G+++G+  C+DLRFPEL  +  L+GAE+ V+P+AW RGP 
Sbjct: 132 YRESSVFSPGREPV-VADLKGLRLGIAVCFDLRFPELFRSMFLRGAEVFVVPSAWYRGPY 190

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K   W  L AARA + T Y+VA  + G    G S +  P G  +    E    I  ++  
Sbjct: 191 KVEQWKALTAARAHENTSYLVAVNQVGESFTGHSLVATPLGHLLVDLGEGERSIAVDLDE 250

Query: 239 ERVRQVRAQLPVLNNRRFAPPQ 260
             +   R ++PV +  R    +
Sbjct: 251 GELASARERIPVRDLLRLELYR 272


>UniRef50_Q1YU23 Hydrolase, carbon-nitrogen family protein n=1 Tax=gamma
           proteobacterium HTCC2207 RepID=Q1YU23_9GAMM
          Length = 281

 Score =  271 bits (695), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 68/278 (24%), Positives = 121/278 (43%), Gaps = 23/278 (8%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            + AA Q       ++N     +L+ QAAE  + L  LPE        D       A+  
Sbjct: 7   FIAAAVQLRPQQSLQQNLAAAGALIEQAAEAGSRLVVLPENFAYLGRKDLTEVG-LAEQS 65

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYDA- 116
            G     L ++++R+ +  +      S     R +         G++V  Y K+HL+D  
Sbjct: 66  TGPAYEFLAKQAQRHSLWLVGGTVPVSDANLSRPFARSWLFDPQGDLVQHYDKIHLFDVD 125

Query: 117 -----------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
                         +ES    +      + E +  ++G+  CYDLRF EL    A   A+
Sbjct: 126 VPTSKEGILQQATYRESDDYRSAAT-VVVAETDPCRLGMSVCYDLRFAELFRQLADADAQ 184

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGV 220
           ++ +PAA+     +  HW  LL ARA++   +++ A      +      G S I+DP+G 
Sbjct: 185 VVAVPAAFTAATGR-DHWELLLRARAVENQLFVIGANMVDRDHPRRGLWGGSAIVDPWGN 243

Query: 221 TIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
            +A   +   + +AE+  +R+ ++RA++PV  +R+ A 
Sbjct: 244 VLARVDDEAGVAIAEINLDRLDEIRAKMPVAQHRKLAL 281


>UniRef50_UPI0001BC35FB amidohydrolase n=1 Tax=Butyrivibrio crossotus DSM 2876
           RepID=UPI0001BC35FB
          Length = 258

 Score =  271 bits (694), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 56/266 (21%), Positives = 106/266 (39%), Gaps = 16/266 (6%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +   Q  +     E+N       +   +++   L   PE  +       +      + 
Sbjct: 1   MRIGICQTDIFFEDKERNLNAAEKYIKAVSDSKVRLALFPEMSMTGFTMKPECFY---ED 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            +G     + + + +  +            G  +N  V +   G I+  Y K+H +    
Sbjct: 58  EKGRTYSVMAKLASKYNIYIGYGYISRKNSG-YYNTYVIIDNLGKIICSYDKIHPFTYAG 116

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E R  + G+ +    +++ + V  + CYDLRFPEL   +A + A+++ + A +     
Sbjct: 117 --EDRVYEKGSSL-SFCQIDDITVCPLICYDLRFPELF-IKASKKADLITVAANFGGPRD 172

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
              HW  LL ARA++   Y+      G       +G S  + P G  I+ A E   +I+A
Sbjct: 173 G--HWQVLLKARAIENQTYIAGINRAGEDVSTYYMGHSMAVSPKGDVISMAGEKEDIIIA 230

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
           ++  E   + R + PV N+ R    +
Sbjct: 231 DIDKEEEYEYRKKFPVRNDFRPEIYK 256


>UniRef50_C0ZEK3 Beta-alanine synthase n=59 Tax=Bacteria RepID=C0ZEK3_BREBN
          Length = 296

 Score =  271 bits (693), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 64/286 (22%), Positives = 102/286 (35%), Gaps = 27/286 (9%)

Query: 1   MLVAAGQ--FAVTSV------WEKNAEICASLMAQAAENDASLFALPEALLARDD---HD 49
           + +   Q    V          EK  E    ++ +AA   A +  L E            
Sbjct: 5   IRIGLIQAKNDVHGDEPVHLHKEKAIEKHERMVREAAAKGAQIICLQEIFYGPYFCAEQQ 64

Query: 50  ADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARY 108
                 + ++  G  +      ++      IL ++     G  +N    +   G  + +Y
Sbjct: 65  PKWYESAEEVPNGPTVQHFSSLARELGTVLILPVYERVGIGTYYNTAAVIDADGTYLGKY 124

Query: 109 AKLHLYDAF------AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQ 162
            K H+             E      GN   P+ E    KVG+  CYD  FPE A    L 
Sbjct: 125 RKQHIPHVGVGSSGCGFWEKYYFKPGNLGYPVFETVFAKVGVYICYDRHFPEGARLLGLN 184

Query: 163 GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN-------KNIGQSRII 215
           GAEI+  P+A     L E+ W     A A+    Y+ A    G        +  GQS ++
Sbjct: 185 GAEIVFNPSA-TVAGLSEYLWKLEQPAHAVANGYYVAAINRVGTEAPWNMGEFYGQSYLV 243

Query: 216 DPFGVTIAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           DP G  +A  S +   +I+AE+    + +VR       +RR    +
Sbjct: 244 DPRGQFVAMGSRDQDEVILAEMDRNTIHEVRDTWQFYRDRRPETYE 289


>UniRef50_C0D6C3 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0D6C3_9CLOT
          Length = 289

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 66/264 (25%), Positives = 108/264 (40%), Gaps = 13/264 (4%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M+ A  Q         KN       + +AA+  A    LPE               +  +
Sbjct: 18  MIAAVIQMNCEPGNIRKNVAAARDFIRKAADKGAEWAVLPELFQTGYLLGGRDREYAGPV 77

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
             GE L  +   ++   +     I      G+ ++  V +    ++  Y K+HL+     
Sbjct: 78  PGGEALCWMEETAREFGIMLTGGIIEEQ-GGKLYDTAVTVSQHGLLGAYRKIHLWGG--- 133

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E  R   GN+    ++    K+G+  CY+  FPE A  Q L+GA  L   AA+     +
Sbjct: 134 -EKERFTPGNDTGTPMDCGNWKIGMQICYEAGFPEGARLQVLKGANALAYVAAFGAA--R 190

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPALIMA 234
              W     ARAL+  CY++A+  CG +       G+SRI+ P G  +A   E   + +A
Sbjct: 191 AEVWDLATRARALENGCYVLASDRCGTEPCGTKFAGRSRIVAPDGTILAQVEEGEGIAVA 250

Query: 235 EVTPERVRQVRAQLPVLNNRRFAP 258
           ++    ++Q RA LP L + R   
Sbjct: 251 KLELSNIQQQRAVLPYLKDLRTDL 274


>UniRef50_Q1QTM0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QTM0_CHRSD
          Length = 260

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 64/262 (24%), Positives = 101/262 (38%), Gaps = 14/262 (5%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +   Q          N    A    QA    A L  LPE  L+  +   +   + A+ 
Sbjct: 1   MKLMLAQTDPVCGDVAANLASLARQCQQAVAAGADLLVLPELALSGYNI-FERLEELAEP 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
           + G    R    +  + +  +  +      GR  N  V +   G  +A Y K  L+D   
Sbjct: 60  VGGPIAQRAAELAAEHELFLLFGLAERQADGRLTNSAVLIDDRGERIATYHKRQLWD--- 116

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +E     AG E   ++E    ++GLM CYD  FPE+A A A QGA++++ P A +    
Sbjct: 117 -REHAFFAAG-EDCCVVETRLGRLGLMICYDNEFPEVARALATQGAQVILSPTANMVPNA 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMA 234
           +         ARALD  C++      G        G S I  P G  +    +    ++ 
Sbjct: 175 ERQALQI--RARALDNQCFVACINRAGEEAELHYCGNSLIAGPDGEVLGRLGDAAGSLVV 232

Query: 235 EVTPERVRQVRAQLPVLNNRRF 256
           ++   R+   RA    L + R 
Sbjct: 233 DIDLSRIDASRAHQDYLQDLRP 254


>UniRef50_C4DVK2 Predicted amidohydrolase n=1 Tax=Stackebrandtia nassauensis DSM
           44728 RepID=C4DVK2_9ACTO
          Length = 272

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 88/258 (34%), Positives = 136/258 (52%), Gaps = 3/258 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           +LV   Q        +N   C   + +A      L   PE + +    D       A+ L
Sbjct: 7   LLVGCVQMRSDLDPGENLRQCLRYLDEARTAGVDLLIFPETVSS--RVDDPSRAPQAESL 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +  F+  L + ++   +T I  +   +   R +N LVAL+ G  VARY K+HLYDA A+ 
Sbjct: 65  DDGFVAGLAKATEGLDLTVIAGVTE-THDDRPFNTLVALRDGQRVARYRKIHLYDACAMA 123

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES  +  G+       V+G +VG+MTCYD+RFPEL+   A +GA++L +P +WVRGPLKE
Sbjct: 124 ESDTIAPGDGPVSTFAVKGFEVGMMTCYDIRFPELSRLLAERGADLLAVPTSWVRGPLKE 183

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
            HW+T   ARAL+ T Y+  A + G   +G + ++ P GV ++  ++   L+ A +  + 
Sbjct: 184 EHWTTFCKARALENTVYLAGACQTGGSRVGLTSVVAPDGVIVSRLAQHEGLVTARIGRDA 243

Query: 241 VRQVRAQLPVLNNRRFAP 258
           +   R   P+L  RRFA 
Sbjct: 244 LTAAREAFPLLEQRRFAI 261


>UniRef50_D0L1I4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Halothiobacillus neapolitanus c2
           RepID=D0L1I4_HALNC
          Length = 294

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 81/282 (28%), Positives = 126/282 (44%), Gaps = 30/282 (10%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE--ALLARDDHDADLSVKSAQL 59
            +AA Q    + W +N  + A L++ AAE  A +  LPE    +  + H+       A+ 
Sbjct: 14  KIAAIQLNGKATWAENQPVIARLVSDAAEAGAEVIVLPENLYAMPANPHELLALGLGAEG 73

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPG-----RAWNMLVALQ-AGNIVARYAKLHL 113
                L  L+  ++   +  +         G     + W+    +   G I A+Y K+HL
Sbjct: 74  ENAP-LDWLQTLARFKGVWLVAGTLPIRADGGSNEGKLWSRSYVIDSKGEIQAKYDKIHL 132

Query: 114 YD-------------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA 160
           +D             A + +ES +   G E+  + E    ++G+  C+DLRFPEL     
Sbjct: 133 FDVDVPPRRSAQSATAESYRESDQFLHGTELVLV-ETPAGRLGMAICFDLRFPELFRRLT 191

Query: 161 LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRII 215
            QGAE + LP+A+        HW  LL ARA++   YMVA+ + G         G S ++
Sbjct: 192 DQGAEWICLPSAFT-ETTGRAHWEPLLRARAIENQVYMVASAQVGVHASGRKTFGHSMVV 250

Query: 216 DPFGVTIAAASE-MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           DP+G  +A A       +MAE+  E    VR Q PVL+ RR 
Sbjct: 251 DPWGTVLANAKTLADCFVMAEIDAEAQAHVRQQFPVLDLRRL 292


>UniRef50_C7N2Y0 Predicted amidohydrolase n=1 Tax=Slackia heliotrinireducens DSM
           20476 RepID=C7N2Y0_SLAHD
          Length = 270

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 72/267 (26%), Positives = 126/267 (47%), Gaps = 9/267 (3%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A  Q +                 +AA   A L   PE  +     D++   + ++ L
Sbjct: 3   LTIALAQ-SGFPKKGDAIAQAERYAEKAAAAGAQLLVFPENFMLPGILDSEGVKEISEPL 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG-RAWNMLVALQAGNI-VARYAKLHLYDAFA 118
           +G F   +   + R+ +  +  I   +  G + +N  V + A  +    Y K HLYDA  
Sbjct: 62  DGPFARAMADIALRHHLWIVYVIFEENPDGGQPFNTAVTVDAEGVQRGAYRKCHLYDAHG 121

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + ES R  AG+++   ++     +G+  CYDLRFPE+A A A+ G ++++ P+AW  GP 
Sbjct: 122 VLESDRSVAGDQLPQPVDTPFGPLGVAICYDLRFPEVARALAVAGCKLVLFPSAWNAGPR 181

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEM------PALI 232
           K  HW+TLL ARA++   ++      G +  G++ + DP G  +A+A           L+
Sbjct: 182 KVKHWTTLLRARAIENELFVAGICHAGKRYTGKTLVADPLGRIVASARGSSKGNAPQDLV 241

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +  +  + V   R  +PVL++RR    
Sbjct: 242 ICTIDTDAVESARDAMPVLDHRRPELY 268


>UniRef50_C7NXL9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Halobacteriaceae RepID=C7NXL9_HALMD
          Length = 270

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 82/273 (30%), Positives = 124/273 (45%), Gaps = 23/273 (8%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q  V     E N E   +++ +AA+    L ALPE          D   ++A+ 
Sbjct: 1   MKIALAQHRVEAGTVEANVERATAMIERAADRGVGLVALPELFATGY-FAFDAYARTAES 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPS------------TPGRAWNMLVALQ-AGNIVA 106
           L G  L RLR  +    +  +    V                    N  V     G   +
Sbjct: 60  LTGPTLTRLRETAAEQDLALLAGSIVEDLAASHAAGIETPATEGYANTSVLFDSDGRRRS 119

Query: 107 RYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI 166
            Y K HL+   +  E   ++ G  I    ++ G  VG+ TCYDLRFPEL    A +G  +
Sbjct: 120 VYRKHHLFGYGSA-EQDLLEPGERI-QTADIGGFTVGVTTCYDLRFPELYRELADRGVTL 177

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTI 222
           +++P+AW     +  HWS L  ARA++   Y+ AA   G  +     G+S + DP+G  I
Sbjct: 178 VLVPSAWPYP--RVEHWSVLPKARAVENLTYVAAANGVGTFDGEALLGRSTVYDPWGTPI 235

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           A+  + PAL+ A++ P+RV  VR   P L++RR
Sbjct: 236 ASTGDEPALVTADLDPDRVAAVRESFPALDDRR 268


>UniRef50_A4SSL0 Beta-ureidopropionase n=2 Tax=Gammaproteobacteria
           RepID=A4SSL0_AERS4
          Length = 277

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 76/270 (28%), Positives = 116/270 (42%), Gaps = 17/270 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +AA Q      W+ N E  A+ +A        L  LPE               + ++ 
Sbjct: 1   MWLAAIQLVSGRHWQDNREQIAAELAALPAGRPLLVLLPENFAL-FGERQGYLDGAERIG 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYDA- 116
           EG    +L   +K   +  +      + PG        +     G +   Y K+HL+D  
Sbjct: 60  EGPIQQQLAAWAKEYGIWLVAGAMPTAIPGSAHIHTSSLVFDPAGELKGHYHKIHLFDVD 119

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES     G +   L++     +GL  CYDLRFPEL    A  GA +L++PA
Sbjct: 120 VADNQGRYRESETFSPGQD-CVLIDSPFGPLGLSICYDLRFPELYRQLARAGARVLLVPA 178

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGE-----CGNKNIGQSRIIDPFGVTIAAAS 226
           A+      E HW  LL ARA++  CY+VAA +      G    G S +IDP+G  +A   
Sbjct: 179 AFTA-VTGEAHWEPLLRARAIENQCYVVAANQGGTHETGRHTWGHSMVIDPWGRVLACQP 237

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
              A ++A + PE   +++  +PVL + R 
Sbjct: 238 SGRATVLAAMDPELGDELKRTMPVLQHARL 267


>UniRef50_A2Q9D7 Catalytic activity: nitrilases catalyze a nitrile + H(2)O <=> a
           carboxylate + NH(3) n=2 Tax=Dikarya RepID=A2Q9D7_ASPNC
          Length = 274

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 89/270 (32%), Positives = 140/270 (51%), Gaps = 17/270 (6%)

Query: 4   AAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGE 63
           A GQ   T+    N   C +L+ +AA   A    LPEA        A+    +  + + E
Sbjct: 5   AVGQLCSTASLAANLAQCQTLVRKAAAAGAKALFLPEASDYIASSPAETISLARSVQDSE 64

Query: 64  FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD-----AF 117
           F+  L++E++   +   + IH P+  GR  N L+ +   GNI  RY K+HL+D       
Sbjct: 65  FVLGLQKEAQLANLHINVGIHEPAANGRIKNTLIWINEQGNITQRYQKVHLFDVDIKGGP 124

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
            ++ES  V+ G EI P  E    +VGL  C+DLRFPE++LA   Q A+I+  P+A+   P
Sbjct: 125 VLKESASVEKGMEILPPFETPVGRVGLSICFDLRFPEISLALRRQNAQIITYPSAFTV-P 183

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE---MP 229
               HW TLL ARA++T  Y++AA + G  N      G S I++P+G  +A   +    P
Sbjct: 184 TGTAHWETLLRARAIETQSYVIAAAQAGPHNEKRRSYGHSMIVNPWGEVVAKLGDEYQEP 243

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            + +A++  + + +VR ++P+L  RR    
Sbjct: 244 QIAVADIDLDLLAKVRREMPLL--RRTDIY 271


>UniRef50_D1A7Y1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Streptosporangineae RepID=D1A7Y1_THECD
          Length = 261

 Score =  269 bits (690), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 96/266 (36%), Positives = 145/266 (54%), Gaps = 16/266 (6%)

Query: 4   AAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGE 63
           A  Q  V     +N E     +A+A    A L   PEA+  R  +D       A+ LE  
Sbjct: 2   ALCQIPVGDDPAENLEQVRRALARA--EGADLAVFPEAVPVRFGND---LTAVAEPLEQG 56

Query: 64  FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQES 122
           F G LR+ ++ +    I  +  P+  GR +N  VA+  +G  V  Y K+HL+DAF  +ES
Sbjct: 57  FAGELRKLAREHGTALIAGVFEPAGDGRVYNTAVAIDASGRPVGAYRKIHLFDAFGDRES 116

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
            RV  G+    ++E+ G ++GL+TCYD+RFPELA A   +GA++LV+ AAW +G  KE H
Sbjct: 117 ARVAPGDAPV-VVELAGARIGLITCYDVRFPELARALVDRGAQVLVIIAAWAQGVFKEEH 175

Query: 183 WSTLLAARALDTTCYMVAAGECGNKN---------IGQSRIIDPFGVTIAAASEMPALIM 233
           W+TL+ ARA++ T ++VA  +  ++          +G+S +IDP G  +A     PA+ +
Sbjct: 176 WTTLVRARAIENTTWVVAVDKAPDRTRPPEGGPGGVGRSMLIDPMGTVVADLGPFPAVRV 235

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAPP 259
           AE+  E   +VR  LP L +RR    
Sbjct: 236 AEIDQEVTERVRRILPSLQHRRPDAY 261


>UniRef50_A5G317 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Alphaproteobacteria RepID=A5G317_ACICJ
          Length = 284

 Score =  269 bits (690), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 83/281 (29%), Positives = 127/281 (45%), Gaps = 27/281 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQA-AENDASLFALPEALLARDDHDADLSVKSAQL 59
           + ++  Q    +    N      L+  A A +   L +LPE        D     ++A++
Sbjct: 7   LRLSVIQMTPGAEKGANIAQARGLIDAAVAADRPGLVSLPEVWSCLGG-DRAAKTEAAEV 65

Query: 60  LE--------GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNM-LVALQAGNIVARYAK 110
           L         G+    LR  ++R+ +             R +N  LV    G  +ARY K
Sbjct: 66  LPAAGSGETGGDAYEFLRETARRHRIHVHGGSIGEQGGDRLYNTTLVFDPDGREIARYRK 125

Query: 111 LHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
           +HL+D         +ES    AG+ +     + G+ VGL  CYD+RFPEL LA    GA+
Sbjct: 126 IHLFDITTPDGQGYRESATYGAGDAVVT-CRIGGLTVGLSICYDMRFPELYLALHRAGAD 184

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK---------NIGQSRIID 216
           ++++PAA+     K  HW  LL ARA++T C++ AA   G             G S I D
Sbjct: 185 LIMVPAAFTLQTGK-DHWDVLLRARAIETQCWIAAAACVGPHRDGRGETRFTYGNSLIAD 243

Query: 217 PFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFA 257
           P+G  +A  S+ P    A + P R  +VR  +PVL +R+ A
Sbjct: 244 PWGSIVARVSDGPGFATARIDPARGAKVRRDMPVLEHRKLA 284


>UniRef50_Q4Q8W4 Nitrilase, putative n=7 Tax=Trypanosomatidae RepID=Q4Q8W4_LEIMA
          Length = 279

 Score =  269 bits (690), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 63/270 (23%), Positives = 106/270 (39%), Gaps = 12/270 (4%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           V   Q AVT     N +   +++ +AA+  + L  LPE                A     
Sbjct: 7   VTLCQMAVTREKAANIKKAVTMITEAAKRGSKLAVLPECFNCPYGTKYFDEYSEALAPGN 66

Query: 63  EFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLV-ALQAGNIVARYAKLHLY----DA 116
           E    + + +K N +  +       S  G+ +N  +     G +   + K+HL+    D 
Sbjct: 67  ETFDAMSQCAKANSIWIVAGSIPEKSADGKLFNSSMTFGSDGALKHVHRKVHLFCINTDT 126

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
               ES  + AGN+   +   E  K G+  C+D+R+P LA   A QG   +V P A+   
Sbjct: 127 VRFDESEVLSAGNDATAISLDEHTKFGVAICFDIRYPFLAWKYAEQGTSFIVYPGAFNM- 185

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGN---KN--IGQSRIIDPFGVTIAAASEMPAL 231
                HW     ARA+D   Y+       +   +    G S ++DP G  ++   E    
Sbjct: 186 VTGPMHWQLAARARAVDNQQYVFVCSPARDTSAEYVAWGHSMVVDPIGNVLSELDEKEGF 245

Query: 232 IMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +  +V    ++  R ++P+L   R     L
Sbjct: 246 VDWKVDLSVIQDTRNRIPILKGVRDDLYTL 275


>UniRef50_Q46AW4 Putative amidohydrolase n=1 Tax=Methanosarcina barkeri str. Fusaro
           RepID=Q46AW4_METBF
          Length = 287

 Score =  269 bits (690), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 73/288 (25%), Positives = 117/288 (40%), Gaps = 37/288 (12%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q  V     ++N E    +  +A    A L  LPE       +  +    +A+ 
Sbjct: 1   MKVACIQMDVLHCRKQENLEKALHMALKAVRKGAELIVLPEVFSTGFCY--EHFDHAAET 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVP------STPGR-----------------AWNML 96
           L    L  L   S+ N    + ++         S  G                   +N+ 
Sbjct: 59  LPSPLLENLACFSEANDCIIMGSVIEKVALEETSDSGTPADSENSTLSNSSNSPFYYNLG 118

Query: 97  VALQAGNIVARYAKLHLYDAFAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLRFPEL 155
              ++G +   Y K H +      E+     G+ I P+ L+ + +K+G   CYDLRFPE+
Sbjct: 119 FCFESGTLAGSYRKTHPFKT----ENNYFSKGDSIEPISLKKQNLKIGFEICYDLRFPEV 174

Query: 156 ALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQ 211
           A   +L G+++LV  AA+     +  HW+ L  ARA++     +A    G+       G 
Sbjct: 175 ARKLSLAGSDLLVTTAAFPNP--RSEHWNILAKARAIENQIPHIACNRIGSAPDCSYFGN 232

Query: 212 SRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           S IID +G   A A     LI+ ++   R  +VR  +PV  N+R    
Sbjct: 233 SMIIDAWGEVKADAGNKECLIVHDLDLSRKNEVRKMIPVFENQRIELY 280


>UniRef50_UPI00019771AF Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Bifidobacterium bifidum NCIMB 41171
           RepID=UPI00019771AF
          Length = 296

 Score =  269 bits (689), Expect = 7e-71,   Method: Composition-based stats.
 Identities = 120/288 (41%), Positives = 164/288 (56%), Gaps = 27/288 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  QF V    E N +I      QAA+  A L  LPE L+ARD  D   +   AQ L
Sbjct: 7   LKVAVAQFTVRREPEWNLDIIDGYAWQAADAGARLLVLPEGLIARDGDDDMFAAAHAQPL 66

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP--------------STPGRAWNMLVALQAGNIVA 106
           +G F   LRR S+   +T + T+H                +T  R  N+ V +  G ++A
Sbjct: 67  DGPFATGLRRISEERHITLMGTVHAVPGAADAVPDKPASCATDSRVSNVFVVIHDGALIA 126

Query: 107 RYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI 166
            Y KLHLYDAFA +ES  V +G E+ P++E++G  VG+MTCYD+RFPE+A + A++GA++
Sbjct: 127 TYRKLHLYDAFAARESDTVRSGTELPPIVEIDGWHVGVMTCYDVRFPEVARSLAVRGADV 186

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAAS 226
           +++ AAWVRG LKE HW  + AARAL+ TCY++A  E   +NIG SR IDP G  IA A 
Sbjct: 187 IIVSAAWVRGRLKERHWKLMTAARALENTCYVLACSEVSARNIGCSRAIDPLGEVIAQAG 246

Query: 227 EMPA-------------LIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +                +++A +  E +   R  LPVL NRRFA PQL
Sbjct: 247 DGQGWLCGQGEAGGQAGMLIARLHREVLESARRTLPVLENRRFADPQL 294


>UniRef50_B6B254 Hydrolase in PqqF 5'region n=1 Tax=Rhodobacterales bacterium
           HTCC2083 RepID=B6B254_9RHOB
          Length = 261

 Score =  269 bits (689), Expect = 7e-71,   Method: Composition-based stats.
 Identities = 68/267 (25%), Positives = 118/267 (44%), Gaps = 12/267 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q         +NA +     A A   +A L   PE  L   +  AD   K A+ 
Sbjct: 1   MKLAIFQMNSVDRSVTENAALFDQACADAKSGNADLIIFPEMALTGYNIGADRIRKLAEP 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
            +G  +  LR  +K + +  +          + +N  V +  AG++++   K HL+    
Sbjct: 61  CDGPMIQTLRDMAKHHRIGVVCGFPELDGE-QVFNAAVIIDAAGSVLSICRKAHLFGDV- 118

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             +       + + PL++     VG   CYD+ FPEL  A AL GA+I+++P A +   +
Sbjct: 119 --DRAAFSPADTLCPLVQFGDWSVGFAICYDVEFPELVRAYALAGADIVLVPTANMLPYV 176

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMA 234
                + ++ ARA +   Y+  A   G     +  G S ++ P G  +A A     L++A
Sbjct: 177 GIA--TRVVPARAEENEIYVAYANRVGREGAFEYCGLSCVVGPDGNDVARAGRNEELMIA 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQL 261
           +++ E +  +R+ L  LN+RR     L
Sbjct: 235 DISKETIAHIRSSLSHLNDRRSDLYPL 261


>UniRef50_D0LZ94 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Bacteria RepID=D0LZ94_HALO1
          Length = 296

 Score =  269 bits (689), Expect = 7e-71,   Method: Composition-based stats.
 Identities = 78/279 (27%), Positives = 130/279 (46%), Gaps = 28/279 (10%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSA--- 57
             +AA Q       +KN E+C   +A AA   A +  LPE        + D    +    
Sbjct: 10  FRLAALQMCAGDDRDKNLELCDRQVAAAASAGAEMVVLPENFAYLGHSEGDRMAAAELLD 69

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVP-----------STPGRAWNMLVALQAGN-IV 105
           +   G  L  L+R +  + +  +                     +A+N  V +  G  +V
Sbjct: 70  EREPGPILAALKRMATVHGVWLVGGGMAERIPEREVKDGIDPDKQAFNTCVVVAPGGALV 129

Query: 106 ARYAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA 160
           +RY K+HL+D       +++ES    AG+EI  + E    ++GL  CYDLRFPE+  A  
Sbjct: 130 SRYRKIHLFDADIPDGPSLRESSGTVAGHEIG-VCETPLARLGLTVCYDLRFPEIYRALC 188

Query: 161 L-QGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRI 214
           + +GAE++V+P+A+        HW  LL ARA++  C++VAA + G  N      G + I
Sbjct: 189 VHEGAELVVVPSAFTA-RTGAAHWHVLLRARAIENQCFIVAAAQVGQHNERRNSYGHALI 247

Query: 215 IDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN 253
           +DP+G  +A   +   L +A++    + Q R ++P   +
Sbjct: 248 VDPWGTILAEVEDGEGLAIADIDLALIEQTRQRMPCHQH 286


>UniRef50_C1E770 Predicted protein (Fragment) n=1 Tax=Micromonas sp. RCC299
           RepID=C1E770_9CHLO
          Length = 316

 Score =  269 bits (688), Expect = 9e-71,   Method: Composition-based stats.
 Identities = 68/308 (22%), Positives = 119/308 (38%), Gaps = 51/308 (16%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q  V      N     + +  AA   A+L  LPE       +D+      A+++
Sbjct: 8   VKVALLQLPVGEDKSLNIANARAAIEDAAREGAALVVLPEMWNCPYSNDS--FPSYAEII 65

Query: 61  ----------------------------------EGEFLGRLRRESKRNMMTTILTIHVP 86
                                             +   +  L   + R  +  +      
Sbjct: 66  GPAPGRWTGGGGTLAKEDDEDGDEKSAPGDGVGSDAASVAMLSNAAARLGVVVVGGSVPE 125

Query: 87  S--TPGRAWNML-VALQAGNIVARYAKLHLYDA-----FAIQESRRVDAGNEIAPLLEVE 138
                G  +N   V    G ++ ++ K HL+D       + +ES  +  G E+  +++  
Sbjct: 126 RCADTGALYNTCCVFDSDGCLLGKHRKTHLFDVDIPGEISFKESDVLSPGTEL-TVVDTA 184

Query: 139 GMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYM 198
             ++G+  C+D+RFPELA+A A +GA+I+V P A+        HW  L  ARA+D   ++
Sbjct: 185 VGRLGIGICFDVRFPELAMACANRGAQIMVYPGAFNT-VTGPLHWELLQRARAVDNQMFV 243

Query: 199 VAAGE-----CGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNN 253
           +          G +  G S  + P+   IA   E P  +  E+  E++R  R  +P+   
Sbjct: 244 LTCSPSRVPGAGYQAWGHSTAVGPWAEVIATTDEKPGTVHCELDMEQIRVRRRNMPLEKQ 303

Query: 254 RRFAPPQL 261
           RR    +L
Sbjct: 304 RRGDVYEL 311


>UniRef50_C8S929 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Archaeoglobaceae RepID=C8S929_FERPL
          Length = 250

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 73/256 (28%), Positives = 125/256 (48%), Gaps = 14/256 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLAR-DDHDADLSVKSAQL 59
           M+VA  Q  +    E N     SL+ +A +++A +  LPEA        +        + 
Sbjct: 1   MIVAVAQQRIVEDVEVNKMKALSLVKRAIQHEAKIVVLPEASNTGLFPENFGKVRSLEEE 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           L+      + + S+R  +  I  +   S  G  +N +  +  G ++ +Y+K+ L+     
Sbjct: 61  LD-----LILKLSERKDILVIAGVVERS-EGNLFNSVALIYRGEVIGKYSKILLFPLN-- 112

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +E + + AG E+  + E +  K+G++ CY++RFPE+A      GAEIL +PA +     +
Sbjct: 113 EERKYLTAGKEL-KVFETDFGKIGVLVCYEVRFPEMARKLMKMGAEILAVPAEFPAE--R 169

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK--NIGQSRIIDPFGVTIAAASEMPALIMAEVT 237
             HW TLL ARA++   Y++ A          G S I+DP G  +  A  +  +I+ EV 
Sbjct: 170 IEHWRTLLRARAIENQFYVLGANCVSPDGFYGGNSMIVDPMGNVVNEAGNLQEIIIGEVN 229

Query: 238 PERVRQVRAQLPVLNN 253
            E VR+VR + P L +
Sbjct: 230 LEYVRRVREEYPFLKD 245


>UniRef50_Q6C005 YALI0F29139p n=1 Tax=Yarrowia lipolytica RepID=Q6C005_YARLI
          Length = 289

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 92/286 (32%), Positives = 136/286 (47%), Gaps = 25/286 (8%)

Query: 1   MLVAAG-QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +AA  QF  T+    NA I A L+ +AA   A    LPEA         +    +   
Sbjct: 1   MTLAAVGQFCATNSLTHNASIVAGLVHRAAALGAQALFLPEASDYISGSPKEGLSLARNA 60

Query: 60  LEGEFLGRLRRESKR------NMMTTILTIHVPSTP-GRAWNMLVALQ-AGNIVARYAKL 111
                +  +R   K       + +   + +H  S+   R  N L+ L   G+IV RY K+
Sbjct: 61  ENSPMIAAIREAQKEIKQSGMSGIEVSVGVHELSSSSDRVRNTLLWLDSNGDIVNRYQKV 120

Query: 112 HLYDAFA-----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI 166
           HL+D        +QES+ V+ G+E+    E     VG   CYD+RFPELAL    QGA+I
Sbjct: 121 HLFDVEVPNGPILQESKSVEPGSELPKPFETPVGTVGPAICYDIRFPELALLLRKQGAQI 180

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-------IGQSRIIDPFG 219
           L  P+A+        HW  L  ARA+DT CY++     G           G + IIDP+G
Sbjct: 181 LQFPSAFTV-RTGAAHWHVLARARAIDTQCYVMMPALVGKHTEDGKRESYGHAMIIDPWG 239

Query: 220 VTIAAASE---MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
             +A AS+     A+I+A++  E++++VR  +P+ + RR     LL
Sbjct: 240 TVLAEASDIDSSAAVIVADINLEQLKKVRTNMPLWDQRRNDVYSLL 285


>UniRef50_A4XQL4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=33 Tax=Proteobacteria RepID=A4XQL4_PSEMY
          Length = 286

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 77/274 (28%), Positives = 118/274 (43%), Gaps = 18/274 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q       + N  +   ++ +AA+  A L  LPE   A    D      +    
Sbjct: 5   MNLAVIQMVSQDDVQSNLRLARRMLERAAQGGARLVVLPENFAAMGRRDLTAIGHAEAAG 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP----STPGRAWNMLVALQA-GNIVARYAKLHLYD 115
           EG  L  L++ ++   +  +             GR     + +   G  VARY KLHL+D
Sbjct: 65  EGPILPWLKQAARDLSLWIVAGTLPLPPDDEPQGRPHACSLLIDEQGERVARYDKLHLFD 124

Query: 116 A------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
                     +ES     G  +  + +    ++GL  CYDLRFPEL  A    GAE++ +
Sbjct: 125 VDVTDNRGRYRESDDFVHGQRLV-VADTPVGRLGLTVCYDLRFPELFGALREAGAELISV 183

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAA 224
           PAA+        HW  L  ARA++T CY++AAG+ G         G S IIDP+G  +  
Sbjct: 184 PAAFTA-VTGAAHWQVLTRARAIETQCYILAAGQGGEHPGQRLTFGHSAIIDPWGTVLVE 242

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
             +    ++A         +R ++PV  +RRF  
Sbjct: 243 QDQGEGALLAARDAAEQAAIRQRMPVQQHRRFFL 276


>UniRef50_A3WPW5 Predicted amidohydrolase, nitrilase family protien n=2
           Tax=Idiomarina RepID=A3WPW5_9GAMM
          Length = 279

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 75/268 (27%), Positives = 122/268 (45%), Gaps = 14/268 (5%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           ++A Q +      +N  +   L+ Q  E    L  +PEA       D      +  +  G
Sbjct: 6   LSAIQLSSFKTPTENLALLERLLEQLPEQRPQLVVVPEAFSCFGAGDRAQLDMAEPVGNG 65

Query: 63  EFLGRLRRESKRNMMTTILTIHVPSTPGRA-WNMLVALQAGNIVARYAKLHLYDAFA--- 118
               RL   +K++ +  +          R     L     G  +ARY K+HL+D      
Sbjct: 66  PVQQRLSELAKQHEIYLVGGTIPLQAGERFAAASLCYGPDGRCLARYDKIHLFDVDVADN 125

Query: 119 ---IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +ESR   AG+ I  + ++    VG+  CYDLRFPEL  A   +GA+I++LP+A+  
Sbjct: 126 TRQYRESRWTRAGSSIVTI-DLGFAVVGMAVCYDLRFPELFKALRAKGADIILLPSAFT- 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAASEMPA 230
                 HW  L+ ARA++   YM+A  +      G +  G S I+DP+G  +A  ++   
Sbjct: 184 EVTGAAHWHPLVRARAIEQQVYMLAPNQYGEAANGRRTYGHSMIVDPWGEVVAEQADGEG 243

Query: 231 LIMAEVTPERVRQVRAQLPVLNNRRFAP 258
           ++ A    E++  +RAQ+PV +  R A 
Sbjct: 244 VVSAYFDREKLENIRAQMPVADQTRLAV 271


>UniRef50_A0LQU6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Acidothermus cellulolyticus 11B
           RepID=A0LQU6_ACIC1
          Length = 272

 Score =  267 bits (685), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 78/273 (28%), Positives = 121/273 (44%), Gaps = 24/273 (8%)

Query: 1   MLVAAGQFAVTSV--WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M +   Q  V+    W    +    L+  A+  DA L  LPE  +      +    + A 
Sbjct: 1   MRITILQLEVSDHEPWPDRVDRVVDLV--ASCRDADLVVLPELWVPG-AFASRFFAEVAT 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTP---GRA-WNMLVAL-QAGNIVARYAKLHL 113
            L G  + RL   +K      +    +        R  +N  V L   G I   Y K+HL
Sbjct: 58  ELPGPIIPRLGAVAKELGAFIMAGTFIERADPATDRIGYNTAVLLNPDGAIAHTYRKVHL 117

Query: 114 YDAFAIQESRRVDAGNEIAPLLEVEGMKV------GLMTCYDLRFPELALAQALQGAEIL 167
           +  F   E+R + AGN+      +EG ++      G  TCYDLRFPEL      QG ++L
Sbjct: 118 F-GFHEGEARMLAAGND-VTTCRLEGGRMTETATYGTSTCYDLRFPELYRILVDQGCDLL 175

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIA 223
           V+P+ W     +  HW  L  ARA++   ++VA  E G+    +  G S ++DP+G  +A
Sbjct: 176 VIPSGWPA--QRLEHWRVLTRARAIENQLFVVACNETGHQQGVELAGHSVVVDPWGQVVA 233

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            A     ++  ++    V ++R   PVL +RRF
Sbjct: 234 EAGAGEEILTVDIDLGEVPRIRRDFPVLPDRRF 266


>UniRef50_A1SU00 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Psychromonas ingrahamii 37 RepID=A1SU00_PSYIN
          Length = 274

 Score =  267 bits (683), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 74/268 (27%), Positives = 118/268 (44%), Gaps = 18/268 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE- 61
           ++A Q    S+  +N      L+A  +     L  LPE  L     D D  +  ++ L  
Sbjct: 5   LSAIQMHSLSLPSENLARLRVLLAALSPIPGQLVLLPENALCI--ADKDHYLALSENLGK 62

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQA-GNIVARYAKLHLYDA-- 116
           G +   L   +K      I       +    + +   +     G +++ Y K+HL+DA  
Sbjct: 63  GYYQSLLSALAKHYQCYLICGSFPIKSTITDKIFTTCLVFSPLGELISHYHKMHLFDAQV 122

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGM----KVGLMTCYDLRFPELALAQALQGAEILV 168
                  +ES     G E   L   +      KVGL  CYDLRFP L      QGA+IL+
Sbjct: 123 ADHKGIYKESDTFVPGQE-VKLFNWDCGAYSVKVGLTICYDLRFPGLFQTLRKQGADILL 181

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEM 228
           +PAA+      + HW  LL ARA++  CY++AA +  ++  G S II P+G  +   +E 
Sbjct: 182 VPAAFT-QTTGQAHWLPLLQARAIENQCYIIAANQSSHETYGHSMIISPWGEVLEQLAEG 240

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
              I       ++ ++R  +P+L + RF
Sbjct: 241 EGSIHHLFEKSQIEKIRQAMPILEHNRF 268


>UniRef50_A8PU96 Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS
           7966 RepID=A8PU96_MALGO
          Length = 330

 Score =  266 bits (682), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 73/315 (23%), Positives = 112/315 (35%), Gaps = 62/315 (19%)

Query: 3   VAAGQF-AVTSVWEKNAEICASLMAQA---AEND-ASLFALPEALLARDDHDADLSVKSA 57
           +A  Q   +      N     S++ +A   A N    +  LPE   +      D   K A
Sbjct: 14  IALIQLGRIGPDKMANLRHARSMVVEANKSAPNGRVDMIMLPECFNSPYS--VDQFPKYA 71

Query: 58  QLLEG-----------------------------------------EFLGRLRRESKRNM 76
           +   G                                           L  L   +K   
Sbjct: 72  ESFSGIYEQIKQGGRTSTSRGSRSWPVDNLNNERPLTLTSDFFQKSPTLEMLCNVAKETG 131

Query: 77  MTTILTIHVPSTP--GRAWNM-LVALQAGNIVARYAKLHLYD-----AFAIQESRRVDAG 128
              +           GR +N   V    G +++ + KLHL+D         QES  + AG
Sbjct: 132 TVLVGGSVPEWDEKTGRLYNTSCVLDAQGRLISLHRKLHLFDIDIPGKMTFQESLTLTAG 191

Query: 129 NEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLA 188
           + +  + + +  +  L  CYDLRFPE A   +  GA  ++ P A+         W  LL 
Sbjct: 192 DRL-TIFDCDLGRFALGICYDLRFPESAQIASRLGASTILYPGAFNT-TTGPVAWELLLR 249

Query: 189 ARALDTTCYMVAAGEC----GNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQV 244
           ARA+D   Y +         G    G S ++DP G  I+   E   ++ A + PER+ +V
Sbjct: 250 ARAIDNQVYTIGCSPARPPAGYPAWGHSTVVDPLGQVISTCDEKETVVYATLHPERIAEV 309

Query: 245 RAQLPVLNNRRFAPP 259
           R  +PV + RRF   
Sbjct: 310 RKTVPVSSQRRFDVY 324


>UniRef50_Q6SHH5 Carbon-nitrogen hydrolase family protein n=2 Tax=environmental
           samples RepID=Q6SHH5_9BACT
          Length = 255

 Score =  266 bits (682), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 68/263 (25%), Positives = 113/263 (42%), Gaps = 16/263 (6%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A     +     EKN E     + QA  +   +  LPE        D     K A+L
Sbjct: 1   MKIATISLNIAWQDIEKNLERTEKFVRQAKADGCDVVVLPEVFNTGFIAD---VGKYAEL 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
              +    L++ +  N++  +          +A N+ +   + GN VA+Y+KLH ++   
Sbjct: 58  PNCKTHHALQQFALNNLINIVAGASEKQPNEKAHNIALVFDSHGNEVAKYSKLHPFNYA- 116

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E +   +GNE     E++G+   +  CYDLRFPE+    A +  E++ + A W     
Sbjct: 117 -NEGKYFTSGNETIK-FELDGVACSVFICYDLRFPEIFRQIAEE-VEVIFVIANWPH--T 171

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPALIM 233
           +E HW  LL ARA++  C++V     GN        G S +I+P G  +    +      
Sbjct: 172 REMHWQNLLIARAIENQCFIVGVNRIGNDGVGLKYNGSSMVINPLGEVLLQTDKKTEYAS 231

Query: 234 AEVTPERVRQVRAQLPVLNNRRF 256
            ++    V + R   P L + RF
Sbjct: 232 CDIDTLMVSKTRKDFPFLEDIRF 254


>UniRef50_A8ZSH3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfococcus oleovorans Hxd3 RepID=A8ZSH3_DESOH
          Length = 270

 Score =  266 bits (682), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 74/266 (27%), Positives = 115/266 (43%), Gaps = 14/266 (5%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           +     QF       E N +     +A  A   A L  LPE      D +  L+  +AQ 
Sbjct: 6   IRAGVVQFDTRLGDIEVNLKSALDGIAGLAAQGADLAVLPELWPCGFD-NRHLAAHAAQT 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
                L  +  ++  + M    ++      G    ++V  + G    RY K+HL+ A   
Sbjct: 65  P--RILEIVSAQAAEHSMVIAGSVPEAGPDGICNTLVVMDRDGREAGRYRKIHLFSAGG- 121

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E R    G +   + +    K+GLM CYDLRFPEL    AL GA  +++PA W     +
Sbjct: 122 -EERFFAKG-KAWAVCDTAAGKLGLMICYDLRFPELCRVLALDGAACVIVPAQWPEA--R 177

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAAS-EMPALIMA 234
             HW+ LL ARA++   ++V A  CG+       G S+++ P G  +A A  + P +I+A
Sbjct: 178 IDHWNALLKARAIENQLFVVGANRCGHDPSLAYGGGSQVVSPTGEVLALARADAPQVILA 237

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
            +    +   R  +P L  R     Q
Sbjct: 238 NLDRAVMENFRKHIPCLQERAPESYQ 263


>UniRef50_C9RPM3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85
           RepID=C9RPM3_FIBSS
          Length = 287

 Score =  266 bits (682), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 54/278 (19%), Positives = 95/278 (34%), Gaps = 20/278 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDH--DADLSVKSAQ 58
           + V   Q   T  ++ N +       +    D  L  LPE          +       A 
Sbjct: 4   IKVYTLQGKWTGDFDSNNKWYKDEALKLKGKDIDLLVLPELFHTPYFPFEENADFFDLAI 63

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAF 117
             +   +   +  +K      +         G   N      + G+I   Y K H+ D  
Sbjct: 64  EKDHPIVAEWQEIAKELNAVVVFPFFEKRARGIYHNSAFVFERDGSIAGLYRKSHIPDDP 123

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA--WVR 175
           A  E      G+     ++     +G++ C+D  FPE A   +L+GA++L+ P A  W+ 
Sbjct: 124 AFYEKYYFIPGDTGFEPIKTSAGTLGVLICWDQWFPEAARIMSLKGADVLIYPTAIGWMD 183

Query: 176 GPLKE------HHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAA 225
              KE        W T++   A+    +++AA   G +      G S +  P G  +   
Sbjct: 184 SEPKEIYPRQQDSWMTVMRGHAIANRTFVIAANRSGVEGHLTFWGTSFVAAPDGYILQKC 243

Query: 226 SEMPALI---MAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
              P  +     E+      + R   P   +RR    +
Sbjct: 244 D--PEFLGASYVELDLAETEENRRWWPHFRDRRVDLYK 279


>UniRef50_B1K4S5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=12 Tax=Proteobacteria RepID=B1K4S5_BURCC
          Length = 299

 Score =  266 bits (682), Expect = 5e-70,   Method: Composition-based stats.
 Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 21/276 (7%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARD-DHDADLSVKSAQ 58
             +A  Q        + N       +  AA N A+L  LPE   +     D D ++  A+
Sbjct: 17  FTIACVQMEPRIGAAQHNLATALDRIETAARNGAALIVLPELASSGYVFEDRDEALALAE 76

Query: 59  L-LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
           L  +G         ++R  +  +  I       R +N  +    G  +  Y KLHL+D  
Sbjct: 77  LVPDGPTARAFEAIARRLNVHIVSGIAERDGA-RLYNSALFAGPGGHLGVYRKLHLWD-- 133

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV--- 174
              E R  + G+   P+ +    ++ +  CYD+ FPE      +QGA+++ +P  WV   
Sbjct: 134 --NEKRFFEPGDRGVPVFDTPLGRIAMAICYDVWFPETFRLAVMQGADLVCVPTNWVPMP 191

Query: 175 -RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIA--AASE 227
            +   +    +TL  A A      +  A   G +     IGQS I+   G  +A  A+ +
Sbjct: 192 SQPDDRPGMATTLTMAAAHSNGIAIACADRVGIERDQPFIGQSLIVGGDGWPVAGPASID 251

Query: 228 MPALIMAEVTPERVRQVR---AQLPVLNNRRFAPPQ 260
              ++   +   R R  R   A   VL +RR     
Sbjct: 252 REEIVYGTIDVARTRAGRALNAHNHVLRDRRADIYD 287


>UniRef50_Q6L0F7 Carbon-nitrogen hydrolase family n=1 Tax=Picrophilus torridus
           RepID=Q6L0F7_PICTO
          Length = 256

 Score =  266 bits (681), Expect = 6e-70,   Method: Composition-based stats.
 Identities = 72/253 (28%), Positives = 124/253 (49%), Gaps = 3/253 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + +A  Q   +   E N E        AA N A L   PE  +    +D     ++A+ +
Sbjct: 2   IRIALTQIHSSMDKESNLEKLRKYTEIAASNGADLIVFPEYFMF-YSNDKKYLNENAEPI 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
            G ++  + +    N ++ I+ I+        ++  V +  G++   Y K  LYDAF  +
Sbjct: 61  NGIWVKNVIKIFNENSISGIVCINEL-NDNNVFDTAVYIS-GDVKGYYRKKMLYDAFGYR 118

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES    +GN    L  +  +  G++ CY++RFPEL    +  GA+++++P+ W  GP+KE
Sbjct: 119 ESDIYKSGNGPFNLYRINDISFGILICYEIRFPELFRNYSKNGADMIIIPSGWFSGPVKE 178

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
             W +LL ARAL+ T Y+ ++ +      G S + DP G+    A E   +I  +V  ER
Sbjct: 179 EQWLSLLRARALENTVYIASSNQIYGDFTGISAVADPIGIISERAGESETMIFYDVKKER 238

Query: 241 VRQVRAQLPVLNN 253
           +  VR ++P+L  
Sbjct: 239 INDVRQKMPLLEQ 251


>UniRef50_D1VW19 Hydrolase C26A3.11 n=1 Tax=Peptoniphilus lacrimalis 315-B
           RepID=D1VW19_9FIRM
          Length = 264

 Score =  266 bits (681), Expect = 6e-70,   Method: Composition-based stats.
 Identities = 59/260 (22%), Positives = 106/260 (40%), Gaps = 10/260 (3%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             V   Q A     + N +    L+  A +  A + ALPE       +      K  +  
Sbjct: 4   FKVGMIQIASKGDKDYNLKRMEELVDIACQKGADVVALPEMWNCPYQNS--YFTKFKEQE 61

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAI 119
             E    +++ +KR  +  +      S   + +N      A G  +  Y+K++L+D    
Sbjct: 62  GEESYELMKKLAKRYGIYLVGGSIPISDGDKIYNKSFVFNACGKEIFSYSKINLFDIEGF 121

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
           +ES  +  G  +  + + E    GL+ CYD RFPEL  +    GAE++ +P+ ++    K
Sbjct: 122 KESDTITGGKSLG-VFQTEFANAGLLICYDSRFPELFQSLVNFGAEVIFMPSTFMIKTGK 180

Query: 180 EHHWSTLLAARALDTTCYMVAA-----GECGNKNIGQSRIIDPFGVTIAAASEMPALIMA 234
              W     ARA+DT C++++       E        S I  P+G  +    E   + + 
Sbjct: 181 RF-WELCNRARAMDTQCFLISPSIARDNELSKNAWAHSMITSPYGEVLLDMGEDEGVEVF 239

Query: 235 EVTPERVRQVRAQLPVLNNR 254
            +  + V++ R   P   +R
Sbjct: 240 SIEADLVKEARKNFPYKKSR 259


>UniRef50_A6TPX2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Clostridia RepID=A6TPX2_ALKMQ
          Length = 269

 Score =  266 bits (680), Expect = 7e-70,   Method: Composition-based stats.
 Identities = 63/254 (24%), Positives = 113/254 (44%), Gaps = 9/254 (3%)

Query: 3   VAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
           VA  Q     +  E N +     + QAA  +  L  LPE          +   + A+  +
Sbjct: 4   VAGIQMTPIMNDVEANLKRGQHFIQQAAAQEVDLIVLPELWTTGYYLSKESFKQLAEHKD 63

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAIQ 120
           G  +  ++ ++ R+  + I      +   + +     +   G +     K  L+     +
Sbjct: 64  GRTVTLMQDQALRSNASIICPFVEITEDKKLYIAAAVIDHRGELRGTVHKSLLWG----R 119

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           E +  + GN   P+ + +  KVG++ CY++ FPE +   ALQG E++V P+ W       
Sbjct: 120 EQQIFEEGNIEYPVFDTKIGKVGILICYEMEFPETSRLLALQGVEMIVCPSVWSLSA--S 177

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEM-PALIMAEVTPE 239
           H W   L ARALD T Y+      GN + G+S+++ P G  +A AS+    L++  +  E
Sbjct: 178 HRWDIQLPARALDNTVYVFGVNTVGNNSCGKSKLVSPLGDVLAEASDRKEELLIRAIDKE 237

Query: 240 RVRQVRAQLPVLNN 253
            +   R  +P L++
Sbjct: 238 ALDWARETVPYLHD 251


>UniRef50_A8RJL1 Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC
           BAA-613 RepID=A8RJL1_9CLOT
          Length = 254

 Score =  266 bits (680), Expect = 7e-70,   Method: Composition-based stats.
 Identities = 73/261 (27%), Positives = 118/261 (45%), Gaps = 17/261 (6%)

Query: 1   MLVAAGQFAVTS--VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M VA  QFAV      E+       ++         L  LPE          +   K ++
Sbjct: 1   MKVAIVQFAVNDEESKEQKIIRMEGILDNL--KGTDLIVLPELWNIGF-FAYEEYAKQSE 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYDAF 117
           LL G     L R++K                 + +N   +  + G ++  Y K+HL+ A 
Sbjct: 58  LLTGPTFSSLARKAKELGSYIFTGSISEQDGDKCYNTAGLIDREGRLLGTYRKMHLFAA- 116

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E + ++ G++   +++ E  K+G+  CYD+RFPEL   +   GAEILV  A W    
Sbjct: 117 ---ERQYMERGDKPV-VIDTEFGKIGMSICYDIRFPELFRKEVEMGAEILVNCAGWPYP- 171

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGEC----GNKNIGQSRIIDPFGVTIAAASEMPALIM 233
            +   W+ L   RA++  CYM++        GN  IG+S +IDP+G   AAA  M  ++ 
Sbjct: 172 -RVESWNMLHPVRAMENQCYMLSCCCAGASRGNPFIGRSMVIDPWGTVQAAAGNMETVVK 230

Query: 234 AEVTPERVRQVRAQLPVLNNR 254
           +E+ PE++  +R     L +R
Sbjct: 231 SEIFPEQLAGIRETFTALKDR 251


>UniRef50_UPI0001AEF4A9 hypothetical protein SghaA1_01010 n=1 Tax=Streptomyces ghanaensis
           ATCC 14672 RepID=UPI0001AEF4A9
          Length = 288

 Score =  266 bits (680), Expect = 8e-70,   Method: Composition-based stats.
 Identities = 66/272 (24%), Positives = 109/272 (40%), Gaps = 17/272 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARD-DHDADLSVKSAQ 58
           + VA+ Q A      E+N       + +AA   AS+  LPE   +     D +  +  A+
Sbjct: 13  VTVASCQIAPRVGRVEENRHRIREAIEEAARRGASIVVLPELANSGYVFQDLEELLSVAE 72

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
            L+G  + +    + R  +  +       + GRA+N  V +    I A Y K HL+D   
Sbjct: 73  PLDGATVRQWEELAARLKLVIVGGFAELGSDGRAYNSAVLIDETGIRASYRKAHLWDG-- 130

Query: 119 IQESRR-VDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
             E       G+   P+++    ++G++ CYDL FPE     AL+GAE+L  P  W   P
Sbjct: 131 --EKTWGFTPGDTRPPVVDTPHGRIGMLICYDLEFPEWVRLAALEGAELLCGPVNWPLYP 188

Query: 178 LKEHHWS---TLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAAS-EMP 229
             E         + A A     ++  A   G +     +G S I+D  G  +        
Sbjct: 189 RPEGERPGEVIRVQANAAVNRMFVAVADRTGTERGQDWLGGSVIVDADGYPVTELRLGEE 248

Query: 230 ALIMAEVTPERVRQ--VRAQLPVLNNRRFAPP 259
           A++ A +     R   +  +  V  +RR    
Sbjct: 249 AVVTATLDLTEARDKSISDRNDVHADRRPELY 280


>UniRef50_A0JSW0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Actinomycetales RepID=A0JSW0_ARTS2
          Length = 294

 Score =  266 bits (680), Expect = 8e-70,   Method: Composition-based stats.
 Identities = 85/266 (31%), Positives = 129/266 (48%), Gaps = 17/266 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q        +N +I      +A +  A L   PEA +    +     +  A+ L
Sbjct: 31  VRVALAQIVTGRDISRNLDIVEKYARKAKKGGAQLVVFPEATMRAFGNS---LLDIAEPL 87

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +G +  R+R  ++   +  +  +  P    +  N L+    G + A Y K+HL+DAF   
Sbjct: 88  DGPWATRVRHIAREADIVIVAGMFTPGGGRKVRNTLLVTGPG-VEASYDKIHLFDAFGFA 146

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES  VDAG   +   E+ G+K GL TCYD+RFP L  A A  GAE  ++ A+W  GP K 
Sbjct: 147 ESDTVDAGTRAST-FELGGIKFGLATCYDIRFPALFTANADLGAEANIVCASWGSGPGKV 205

Query: 181 HHWSTLLAARALDTTCYMVAAGEC-----GNK-------NIGQSRIIDPFGVTIAAASEM 228
             W  L  ARA+DTT Y++A G+      G +        +G S ++ P G  +      
Sbjct: 206 DQWRLLARARAVDTTTYVLACGQADPATEGIETKGSAPTGVGHSAVVSPLGEVLEELDAG 265

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNR 254
             L+ A++ P  V++ RA+LPVL NR
Sbjct: 266 TGLMFADLDPAVVKEARAKLPVLANR 291


>UniRef50_B8FEV8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfatibacillum alkenivorans AK-01
           RepID=B8FEV8_DESAA
          Length = 266

 Score =  265 bits (679), Expect = 9e-70,   Method: Composition-based stats.
 Identities = 69/266 (25%), Positives = 109/266 (40%), Gaps = 16/266 (6%)

Query: 2   LVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            +   QF V       N +     +   A+   +L  LPE      D+ A     +    
Sbjct: 5   KIGLVQFDVKLGNPRANIDHVRRAIQDLADQGVNLAVLPEMWSCGFDYSALKDHAAQTPA 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFAI 119
               L  L   ++   +    T+   +  G  +N    +   G++ A Y K+H +     
Sbjct: 65  ---VLDELCSLAENLNLAVSGTMPELTPDG-VYNTHYYINEKGSVQAEYRKVHRFTPAGE 120

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E    + G     L      K GL+TCYDLRFPE + A  L GA +L++ A W    ++
Sbjct: 121 GE---FEPGARSV-LAAAPWGKTGLLTCYDLRFPEQSRALVLAGAIVLIVSAQWPAVRIR 176

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAE 235
             HW  LL ARA++   +++A   CG        G+S +I P+G  IA A     L+ A 
Sbjct: 177 --HWDVLLQARAVENQAFVIACNRCGKDPELVYGGRSAVISPWGEVIAGAGGGETLLTAA 234

Query: 236 VTPERVRQVRAQLPVLNNRRFAPPQL 261
           +    V+  R ++P L +R      L
Sbjct: 235 LNLYEVKDFRTRIPCLEHRIPEAYDL 260


>UniRef50_A1SE99 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=14 Tax=Actinomycetales RepID=A1SE99_NOCSJ
          Length = 280

 Score =  265 bits (679), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 67/274 (24%), Positives = 113/274 (41%), Gaps = 25/274 (9%)

Query: 1   MLVAAGQFAVTSV--WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           + VA  Q A           +  +  + +     A L  LPE         +     +A+
Sbjct: 12  LRVALLQVAYGDDESLSDRVQRVSQWIREV--GPADLVVLPELWAHGG-FASTTWRATAE 68

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGR---------AWNMLVALQAGNIVAR-Y 108
           L+ G  + ++   ++   +       +                WN  V +     V + Y
Sbjct: 69  LMNGPTIAQMASVAREVGVWLHAGSIIERAEDGADRGAERRGLWNTSVLISPQGTVHKTY 128

Query: 109 AKLHLYDAFAIQESRRVDAGNEIAP---LLEVEGMKVGLMTCYDLRFPELALAQALQGAE 165
            K+H +  F   E R ++AG ++A    + +    +VG+ TCYDLRFPEL       GA+
Sbjct: 129 RKIHRF-GFGDGEPRVLEAGTDLAVAELVHDTGASRVGMATCYDLRFPELFRRLGDLGAD 187

Query: 166 ILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVT 221
           ++VLPAAW     +  HW  L  ARAL+   +++     G        G S+++ P G  
Sbjct: 188 VIVLPAAWPMR--RVEHWRLLGRARALENQAWVLQCNTAGTHSGLDMGGHSQVVAPTGEV 245

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           +A       +++ ++    V  VRA  PVL +RR
Sbjct: 246 VAELGSDEDVLLTDIDLNLVASVRADFPVLADRR 279


>UniRef50_A8LPZ9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=28 Tax=Alphaproteobacteria RepID=A8LPZ9_DINSH
          Length = 277

 Score =  265 bits (679), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 104/269 (38%), Gaps = 20/269 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M  A  Q       E N      L AQA    A     PE                 +  
Sbjct: 1   MRAALVQMTSGDDPEANLAQLQGLAAQAVAEGAGFVLSPEVSNCLSTSRTRQRAVLRREA 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHV---PSTPGRAWNMLVALQA-GNIVARYAKLHLYD- 115
           +   L  +R  + R  +  +L           GR  N  + + A G I ARY K+H++D 
Sbjct: 61  DDPMLAAMREFAARRGVWVLLGSLAVTTEDAEGRFANRSILIDAGGGIAARYDKIHMFDV 120

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
               A   +ES     G+    L +    K+G+  CYDLRFP L    A  GAEIL +P+
Sbjct: 121 AVSEAETYRESDGYRPGDRAV-LADTPFGKIGMTVCYDLRFPHLFRDLARAGAEILTVPS 179

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK---------NIGQSRIIDPFGVTI 222
           A+        HW  LL ARA++   +++A  + G             G S  +DP+G  +
Sbjct: 180 AF-SPVTGAAHWEPLLRARAIECGAWVLAPAQTGTHPATRGKARSTHGHSLAVDPWGRVL 238

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVL 251
           A     P +   ++    +   R ++P L
Sbjct: 239 ADGGTAPGVCFVDLDRTEIAAARRKIPSL 267


>UniRef50_C7LN61 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Desulfomicrobium baculatum DSM 4028
           RepID=C7LN61_DESBD
          Length = 270

 Score =  265 bits (678), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 74/265 (27%), Positives = 123/265 (46%), Gaps = 12/265 (4%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +AA Q + +      N +  ++ +   A+    L   PE      D  +     + + 
Sbjct: 1   MKIAAVQLSGLPGDVSGNLDKISAAVQTGAKASCRLLLFPEISDLGYDMPS--IALAGRD 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
                  RL   ++ + +  +  + +P   G   N LVA    G+I+ARY K+HL+ A  
Sbjct: 59  WWPRVRDRLMALAREHDICLVCGVCLPGPDG-LANALVAFGPTGDILARYRKIHLFTATD 117

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E+     G+EI    + EG++ GL  CYDLRFPEL   QAL G + ++L +AW +   
Sbjct: 118 ADETEVFSPGSEIV-CFDFEGVRFGLSVCYDLRFPELYRVQALHGCQAMLLASAWPKR-- 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
           +   W TL AARAL+  C+++ A   G++      G+S  + P G    A+++   +I  
Sbjct: 175 RIDIWQTLCAARALENQCFLLGANRIGDQGAFPFGGRSLFVTPGGEITLASADQEGVITG 234

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPP 259
            V    +  +R  +P L +RR    
Sbjct: 235 TVDLAELAAIRQNIPALAHRRPELY 259


>UniRef50_Q1YMV3 Putative hydratase n=1 Tax=Aurantimonas manganoxydans SI85-9A1
           RepID=Q1YMV3_MOBAS
          Length = 289

 Score =  265 bits (678), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 61/274 (22%), Positives = 109/274 (39%), Gaps = 21/274 (7%)

Query: 3   VAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA--DLSVKSAQL 59
           ++  QF       E+N E    L+A+AA++ + L  LPE   +    ++  +    S  +
Sbjct: 9   ISCAQFEPRIGEVERNVEASLKLIAEAADSGSRLIVLPELCNSGYVLESREEAYALSEDV 68

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
             G  + R    +    +  +          + +N  + +    ++  Y K HL+     
Sbjct: 69  ATGSSIARWASLAAERGLYIVAGFLERDGI-KLYNSAIVIGPDGVIGTYRKNHLW----A 123

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV----R 175
            E+   + G+   P+      +VG++ CYD  FPE     ALQGA+I+ +P  WV    +
Sbjct: 124 DEALYFERGDLGFPVFHTPFGRVGVLICYDGWFPEAWRILALQGADIVCVPTNWVPMAEQ 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIA--AASEMP 229
                   + L    A   +  + A    G +     IGQS I+D  G  +A  A++  P
Sbjct: 184 PAGMPAMANVLCMGAAHSNSMVVAACDRVGTERGQPFIGQSLIVDHNGWPVAGPASASEP 243

Query: 230 ALIMAEVTPERVRQVRAQLPV---LNNRRFAPPQ 260
            L+ A     + R+ R        + +RR     
Sbjct: 244 GLVTAICDLSQARRKRNWNDFNQVMRDRRTDLYG 277


>UniRef50_A6VWN8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Marinomonas RepID=A6VWN8_MARMS
          Length = 277

 Score =  264 bits (677), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 78/275 (28%), Positives = 125/275 (45%), Gaps = 25/275 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q   T  W+ N      L+A AA + A L  LPE +              A+  + 
Sbjct: 6   VAAIQLTSTISWQDNLREVKHLVASAARDGARLVVLPENV---FLFHGKGMRCLAESDDQ 62

Query: 63  EFL-GRLRRESKRNMMTTILTIHV--------PSTPGRAWNMLVALQAGNIV-ARYAKLH 112
             +   +   ++ + +  ++  H              R       +    ++  RY K+H
Sbjct: 63  SVIFKEISALAQEHSIYLVVGSHPSLLRPSGDLVVDERVRQTCWVIGPDGLLYERYDKIH 122

Query: 113 LYD------AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEI 166
           L+D      A + +ES  ++ G     +++V+G KVGL  CYDLRFPEL       GAE+
Sbjct: 123 LFDVTVDDKATSYKESGVIEPGELALKVIDVDGFKVGLSICYDLRFPELYRELTKLGAEV 182

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG-----NKNIGQSRIIDPFGVT 221
           L++PAA+      + HW  LLAARA++  CY++  G+CG      +  G S +  PFG  
Sbjct: 183 LLVPAAFTY-VTGKAHWDILLAARAIENQCYVLGVGQCGWHNETRQTYGHSVLYSPFGER 241

Query: 222 IAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           +A   E P   +  +T   +   R ++P L++RR 
Sbjct: 242 LANLEEEPGYFVFNMTKTALSNCRQKMPCLSHRRL 276


>UniRef50_A4SNH5 Amidohydrolase family protein n=2 Tax=Proteobacteria
           RepID=A4SNH5_AERS4
          Length = 284

 Score =  264 bits (677), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 69/268 (25%), Positives = 114/268 (42%), Gaps = 18/268 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VA  Q       + N     +L+ QAA   A    LPE        +      +A + 
Sbjct: 11  VRVAVLQMVSGDDLDHNLTQAEALLRQAAAEGAEFALLPEYFYLMPADERARVALAAPVS 70

Query: 61  EGEFLGRLRRESKRNMMTTILTI--HVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA- 116
           +   L   +  ++   +  +          PG+  N  + +   G + +RY KLHL+   
Sbjct: 71  DHPLLAWAQGLARELGIWLLAGTLPLESDEPGKMHNSSLLIDPQGALASRYDKLHLFGFC 130

Query: 117 ---FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA-EILVLPAA 172
                  E+  +  G E+     +    +    CYDLRFPEL     L  A + + LPAA
Sbjct: 131 TGQEQYDEAATMSPGREVVS-HPLPWGMLRFGICYDLRFPELFR---LDPAPDFIALPAA 186

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           +        HW  LL ARA++   +++A+ + G+        G S IIDP+G  +A   E
Sbjct: 187 FTH-TTGLAHWELLLRARAVENLAFVLASAQGGHHPGGRRTFGHSMIIDPWGQVLARVEE 245

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
              + +A +     R+VR+QLP L++R+
Sbjct: 246 GHGMAIATLDLAAQRKVRSQLPALSHRK 273


>UniRef50_B8D189 Nitrilase/cyanide hydratase n=1 Tax=Halothermothrix orenii H 168
           RepID=B8D189_HALOH
          Length = 273

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 65/267 (24%), Positives = 109/267 (40%), Gaps = 18/267 (6%)

Query: 3   VAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSAQL 59
           + A Q A   +  E N +   + +A+  +  A +   PE      D D   D     A+ 
Sbjct: 6   IGAVQMASKLADKEGNIKQALTYIAEYGDR-ADILIFPELFTTGYDLDIVGDDYYSLAEK 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQA-GNIVARYAKLHLYDA 116
           + G         ++      I  +           +N    +   G+   +Y K+H+Y A
Sbjct: 65  IPGRTTEIFSEYARMYKTAIIGNMVERDKNVGEILYNTTFVIDKKGDYTGKYRKVHVYPA 124

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
               E      G E  P+  V G+K+GL TCYD  F E+    A +GA+I+ +P+A  +G
Sbjct: 125 ----EFTYFKRGTE-FPVFNVNGVKIGLATCYDHGFGEMFRILARKGAQIIFIPSAIPKG 179

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECG----NKNIGQSRIIDPFGVTIAAASEMPALI 232
              E+       ARA D   + VA    G    +   G S +++P G  I  A +   + 
Sbjct: 180 Y--EYLLKLRTRARAQDNQLFTVAVNSAGKTPNSHFCGNSMVVNPRGEIIQEADDGEGVF 237

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAPP 259
           +AE+  E + + R Q P++ +  F   
Sbjct: 238 LAELDLELIERERKQEPLIRDSAFDLY 264


>UniRef50_C6CAD7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Proteobacteria RepID=C6CAD7_DICDC
          Length = 590

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 62/264 (23%), Positives = 99/264 (37%), Gaps = 20/264 (7%)

Query: 6   GQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDD-HDADLSVKSAQLLEGE 63
            QF       E N     +L+ QAA   A L   PE        +         + + G 
Sbjct: 11  VQFEPLFGAREANITRLLTLVEQAARQGAKLITTPEMATTGYCWYHRQEIAGQVETVPGP 70

Query: 64  FLGRLRRESKRNMMTTILTIHV-PSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQES 122
             GR    + R     +L +    +  G  +N  V +    IV  + K H Y    I E 
Sbjct: 71  TTGRFAALAARYQCYIVLGMPEVEAGTGLYYNSAVLIGPDGIVGCHRKSHPY----ISEP 126

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
           +   AG E   + +    ++G++ C D+ + E A   AL GA+I+   + W+       +
Sbjct: 127 KWAAAG-ERHQVFDTPLGRIGMLICMDIHYVETARLLALAGADIICHISNWLAERTPAPY 185

Query: 183 WSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           W     +RA++  CY++ +   G +      G S II P G  +A   +   +  A +  
Sbjct: 186 W----ISRAMENGCYLLESNRWGLERGVQFSGGSCIIAPDGEILATVDDGDGIAYASLDL 241

Query: 239 ERVRQVRAQL--PVLNNRRFAPPQ 260
             V   R  L  PV   RR     
Sbjct: 242 --VGHPRRVLGEPVFRQRRPELYH 263



 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 51/236 (21%), Positives = 85/236 (36%), Gaps = 31/236 (13%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAEN-DASLFALPEALLARDDHDADLSVKSAQLLE 61
           ++  QF   +    N    A+L  Q  +   + L   PE  +       D   + A  LE
Sbjct: 294 ISVLQFDAGNDIAGNVARMAALARQTIDQQGSELLVFPELAVTGY----DAPEQRAIALE 349

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQE 121
              L  L + +  + +     +       R +N L+ L    +V  Y ++HL  A+    
Sbjct: 350 SPLLRPLLQLAMTHRVWLAFGLAEQDGE-RRYNTLLLLGPEGVVGHYRQIHLPQAYRH-- 406

Query: 122 SRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEH 181
                AG+    + +    ++GL+  +D  FPE A   AL+G +++   AA   G    H
Sbjct: 407 --WASAGDHWG-VFDTALGRLGLLLGHDALFPESARILALEGCDVVACAAALDGGFTGAH 463

Query: 182 ------------------HWSTLLAARALDTTCYMVAAGECGNKNIGQ-SRIIDPF 218
                             HW  L   RA +   Y+  A  C  +  G  S +  P 
Sbjct: 464 PGSRVGQNYPIPTGADPLHWH-LFRTRAGENNLYLAFANRCHAEAQGGYSGVFGPD 518


>UniRef50_Q15ZG7 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Alteromonadales RepID=Q15ZG7_PSEA6
          Length = 276

 Score =  264 bits (675), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 75/270 (27%), Positives = 119/270 (44%), Gaps = 16/270 (5%)

Query: 5   AGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEF 64
           A Q   T    +N       +AQ   N+ +L  LPE        D  L   +  L +G  
Sbjct: 6   ALQMTSTPDVTENLHFVEQQLAQLTVNEPTLVVLPECFACFGGGDKALLSIAESLGDGPI 65

Query: 65  LGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQA-GNIVARYAKLHLYDAF---- 117
             RL   +K+  +  +       +    +     + +   G  V  Y K+HL+D      
Sbjct: 66  QARLMGMAKQYGVWLVAGSMPLKSENPDKFTASCLLINDAGERVTEYQKIHLFDVQVADN 125

Query: 118 --AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGA-EILVLPAAWV 174
                ES+   AG+ +  + +     +GL  CYD+RFP L  A A   A +++ LPAA+ 
Sbjct: 126 TKTYCESKYTQAGSTLVSVPDTPFGHLGLAICYDVRFPGLFQAMAEHKALDVIALPAAFT 185

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMP 229
                E HW  LL+ARA++  CY+VAAG+ G         G S II P+G T+A   +  
Sbjct: 186 -QKTGEAHWQALLSARAIENQCYLVAAGQTGVHANQRQTHGHSCIISPWGETLAELPQSV 244

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            +I A++ P  + ++R  +PV  + +F   
Sbjct: 245 GVINAQLEPAILNRIRRDMPVYAHNKFRSY 274


>UniRef50_Q11M91 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Chelativorans sp. BNC1 RepID=Q11M91_MESSB
          Length = 272

 Score =  264 bits (675), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 80/269 (29%), Positives = 122/269 (45%), Gaps = 17/269 (6%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAEND-ASLFALPEALLARDDHDADLSVKSAQLL 60
            +   Q         N     SL+  A E D +     PE       + A +   +  L 
Sbjct: 3   KITVVQINTRDDKAANLAKLESLVRAAHEADHSDYILTPEHSFCLTANKATMHAAAETLE 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLH-----LY 114
           +GE L R+   ++    T  +   + +  GR +N  V +   G  +A Y K+H     L 
Sbjct: 63  DGEGLRRMASLARELGTTIHIGSILTTRNGRYYNTSVVIGPDGKQLATYDKIHRYDVDLP 122

Query: 115 DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              + +ES   DAGN      +  G  VGL  CYD+RF  L L  A +GA+++ +PAA+ 
Sbjct: 123 SGLSYRESDTNDAGNVAVT-YDHNGTNVGLSVCYDVRFGSLYLELAARGAQVITIPAAFT 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECG--------NKNIGQSRIIDPFGVTIAAAS 226
                  HW TL+ ARA++T CY+ AAG+ G          + G S+I+DP+G  +A  S
Sbjct: 182 FET-GAAHWDTLVRARAIETQCYVAAAGQVGSFPASGGDRASFGNSQIVDPWGKVLARCS 240

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           ++     A + P    +VR  LPV  +RR
Sbjct: 241 DVEGWASAAIDPSYQNRVRQNLPVARHRR 269


>UniRef50_O94660 Probable hydrolase nit2 n=2 Tax=Schizosaccharomyces
           RepID=NIT2_SCHPO
          Length = 276

 Score =  263 bits (674), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 83/279 (29%), Positives = 129/279 (46%), Gaps = 20/279 (7%)

Query: 1   MLVAAG-QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +AA  Q   +    KN  IC  L++QAA   A     PEA      +  +    +   
Sbjct: 1   MTLAAVAQLNSSGSILKNLAICKELISQAAAKGAKCIFFPEASDFIAHNSDEAIELTNHP 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPST-PGRAWNMLVALQA--GNIVARYAKLHLYD- 115
              +F+  +R  + ++ +   + +H PS    +  N  + ++   G I++RY+K HL+D 
Sbjct: 61  DCSKFIRDVRESATKHSIFVNICVHEPSKVKNKLLNSSLFIEPLHGEIISRYSKAHLFDV 120

Query: 116 ----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                  ++ES     G  I P  +    KVG   C+D+RFPE A+     GA I+  P+
Sbjct: 121 EIKNGPTLKESNTTLRGEAILPPCKTPLGKVGSAICFDIRFPEQAIKLRNMGAHIITYPS 180

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAAS 226
           A+        HW  LL ARALD+ CY++A  + G  N      G S I+DP+G  IA  S
Sbjct: 181 AFT-EKTGAAHWEVLLRARALDSQCYVIAPAQGGKHNEKRASYGHSMIVDPWGTVIAQYS 239

Query: 227 EM---PALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
           ++     LI A++    V  VR  +P+L  RR      +
Sbjct: 240 DISSPNGLIFADLDLNLVDHVRTYIPLL--RRNDLYPTI 276


>UniRef50_D2VM50 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VM50_NAEGR
          Length = 300

 Score =  263 bits (673), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 72/298 (24%), Positives = 127/298 (42%), Gaps = 38/298 (12%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q    +    N  +C  L+ +A+E+ ASL   PE          +    S   L
Sbjct: 1   MKIALAQVRSINKIGFNFGVCEKLIKEASEHKASLICFPECFAFMGTSATETIANSG-SL 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPS---TPGRAWNMLVALQA-GNIVARYAKLHLYDA 116
           + E     +  +++  +      +       P + +N  + +   G I+  Y K+HL+D 
Sbjct: 60  DSELFKSYQDLARKYSINISYGGYHEKSSNDPHKIFNSHILVNNNGEIINVYRKVHLFDL 119

Query: 117 FA----IQESRRVDAG-----NEIAPLLEVEGMKVGLMTCYDLRFPELALAQA-LQGAEI 166
                 ++ES   + G     ++   +     +K+GL  CYDLRFPEL +    +  A+I
Sbjct: 120 NTEKVKLKESEITEFGKDLLVDDGGLIFS-NDLKIGLSICYDLRFPELYILLRKMNNAKI 178

Query: 167 LVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVT 221
           L++PAA+ +   +  HW TLL ARA++  CY++A+ + G  N      G S +IDP G  
Sbjct: 179 LLVPAAFTKHTGELGHWKTLLMARAIENQCYVIASAQVGTHNLKRQSYGHSLVIDPLGKI 238

Query: 222 IAAASEMPALI---------------MAEVT--PERVRQVRAQLPVLNNRRFAPPQLL 262
           I                           E+      +++VR  +PV +++R     ++
Sbjct: 239 ILDLGSQEETFDLDIQEKEPFEGKLGFVEIDDWISNIKKVREGMPVFDHKRSDLYDVI 296


>UniRef50_B0X5I4 Hydrolase n=5 Tax=Culicidae RepID=B0X5I4_CULQU
          Length = 279

 Score =  263 bits (673), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 65/275 (23%), Positives = 113/275 (41%), Gaps = 17/275 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAA-ENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q       +       + +  AA    A L  LPE   +     AD   +SA+ 
Sbjct: 6   IKIALLQLDSFPTKQAAISNALTQIRSAAKAKGAKLVILPECWNSTYS--ADEFERSAEK 63

Query: 60  LEG-EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA- 116
           + G E    L   +K   +  +   +     G+  N        G  + +Y K+HL+D  
Sbjct: 64  IPGGETSVALANTAKELGIWLVGGTYPEVDAGKIHNTCAVFGPQGEFIGKYRKMHLFDMD 123

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                   ES  +  G E      VEG+ VG+  CYD RFPE A      G + L+ P+A
Sbjct: 124 IPGICTFSESSVLTPGKEFLT-FSVEGLNVGIGICYDQRFPEFAAIHRQLGTDFLIFPSA 182

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           +        H+  +  ARALD + ++       + +      G S + DP+G  +  A E
Sbjct: 183 F-DTYTGPMHFELIARARALDNSMFVALCAPARDTSKDYVAYGYSTLCDPWGRVVCRAGE 241

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL 262
            P +++ ++    +  ++ ++PVL  +R    +L+
Sbjct: 242 HPEMLVVDLDLTLLEDIKKKIPVLKQKRNDVYELV 276


>UniRef50_B4RQA3 Nitrilase n=28 Tax=Neisseriaceae RepID=B4RQA3_NEIG2
          Length = 281

 Score =  263 bits (673), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 80/270 (29%), Positives = 115/270 (42%), Gaps = 16/270 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q       E N      L+A+AAE  A    LPE  +    +D      +  L 
Sbjct: 15  IRVAAVQMVSGVSPETNVAAMKRLVARAAEQGADWVLLPEYWVLMGANDTGKLALAEPLG 74

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVALQ-AGNIVARYAKLHLYD-- 115
            G F   L   +K   +          +P  G+  N L+     G     Y K+HL+   
Sbjct: 75  GGRFQTALSETAKECGVVLFGGTVPLQSPEAGKVMNTLLVYGCDGVRTGLYHKMHLFGFS 134

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                  E+  + AG E  P L  EGM V    CYD+RFPE          ++L+LPAA+
Sbjct: 135 GLGERYAEADTIRAGRE-VPHLSAEGMPVAAGICYDVRFPEFFR--RQLPFDVLMLPAAF 191

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEM 228
                 + HW  LL ARA++  CY+VAA + G         G S I+DP+G  +    E 
Sbjct: 192 TH-TTGKAHWELLLRARAVENQCYVVAAAQGGLHENGRRTFGHSMIVDPWGDVLDVLPEG 250

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRFAP 258
             ++ A++   R+  VR +LP L +R    
Sbjct: 251 EGIVTADIDANRLNSVRNRLPALKHRVLDA 280


>UniRef50_A7FDR9 Hydrolase, carbon-nitrogen family protein n=45
           Tax=Enterobacteriaceae RepID=A7FDR9_YERP3
          Length = 289

 Score =  263 bits (673), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 67/269 (24%), Positives = 113/269 (42%), Gaps = 19/269 (7%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VA  Q         N       + Q       L   PE  L    + A     + Q  +G
Sbjct: 6   VALLQLCSGENTRDNLAQIEQQIKQL-NAGIKLVMTPENALL-FANAASYRHHAEQHNDG 63

Query: 63  EFLGRLRRESKRNMMTTILTIHV---PSTPGRAWNMLVALQA-GNIVARYAKLHLYDA-- 116
                +R  ++R  +   +         +P    +  +     G + ARY K+H++D   
Sbjct: 64  PLQQEVREMARRYGVWIQVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKIHMFDVDI 123

Query: 117 ----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES     G ++  +++    ++G+  CYDLRFP L  A   QGAEI+ +PAA
Sbjct: 124 NDIHGHYRESDTYQPGQQL-TVVDTPVGRLGMTICYDLRFPGLFQALRAQGAEIISVPAA 182

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASE 227
           + +    E HW TLL ARA++  C ++AA + G         G +  +D +G  I    +
Sbjct: 183 FTK-MTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGHNPD 241

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             A +   +    ++ +R Q+PV+ + RF
Sbjct: 242 AVAALKVRIETAGLKTIRNQMPVMQHNRF 270


>UniRef50_C9RT97 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Geobacillus RepID=C9RT97_GEOSY
          Length = 302

 Score =  262 bits (670), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 61/269 (22%), Positives = 106/269 (39%), Gaps = 19/269 (7%)

Query: 3   VAAGQFAVT-SVWEKNAEICASLMAQAAEN--DASLFALPEALLARDDHDADLSVKSAQL 59
           +A  Q          N     +++ +      +  L   PE         +++  ++AQ 
Sbjct: 7   IALAQMTPADGDIGANLAKMETIIHECKRKFPNVRLLLFPELCTTGYVL-SEMLKEAAQT 65

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            +G     + + ++   +            G  +N L+ +   G  +  Y K+HL     
Sbjct: 66  WDGSTFQHMSQLAQTFQLYIAYGYVEKDHTGNLYNSLMLIDPNGQCIGNYRKIHLTPF-- 123

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E      G E   + + E  ++GLM C+DL FPELA   A+ GAE+L++P AW     
Sbjct: 124 --EKAWFSKGAEPVLV-DTELGRIGLMICWDLAFPELARYLAVHGAELLLVPCAWESPFH 180

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASE--MPALI 232
                     ARA+D T Y+ A  + G+       G S I  P G  IAAA+      L+
Sbjct: 181 APF--QKFAMARAIDNTVYVAACNQIGSSSSFHFFGLSSIYGPDGRKIAAANMNGREELV 238

Query: 233 MAEVTPERVRQVRAQLPVLNN-RRFAPPQ 260
            A +   + + ++     + + RR    +
Sbjct: 239 HAMIDQNQRQALKKHFYTMMDERRIDLYR 267


>UniRef50_Q2NAB0 Nitrilase 1 like protein n=3 Tax=Sphingomonadales
           RepID=Q2NAB0_ERYLH
          Length = 267

 Score =  261 bits (669), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 67/261 (25%), Positives = 110/261 (42%), Gaps = 13/261 (4%)

Query: 8   FAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGR 67
                  E N         +A+   A +   PE  L  D      +   A   +  +  R
Sbjct: 1   MTSGIDPEANFAAIEQAAREASAGGAEMLFTPEMSLLLDRDRKRAAQHIAPQAQSPYPER 60

Query: 68  LRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYD-----AFAIQE 121
           L+  ++   +   +   V     R  N   +    G     Y K+H++D       + +E
Sbjct: 61  LQAIAREAGLWLTVGAPVRVEDDRYANRQWLFYPRGESPVHYDKIHMFDVDLADGESWRE 120

Query: 122 SRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEH 181
           S     G E+  + +    ++GL  CYDLRFP L        A+ + +PAA+ R P    
Sbjct: 121 SNAYRPGEEVVLVDDTPVGRLGLTICYDLRFPALFEELGNARADCIAIPAAFTR-PTGAA 179

Query: 182 HWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAA-SEMPALIMAE 235
           HW TL+ ARA++ + ++VAA + G         G S ++DP+G  +     + P L  A+
Sbjct: 180 HWHTLVRARAIEASAFVVAAAQVGEHEDGRKTYGHSLVVDPWGEVLLDMSGDKPGLGFAD 239

Query: 236 VTPERVRQVRAQLPVLNNRRF 256
           +   R+ +VR Q+P L NRR 
Sbjct: 240 IDLARIEEVRRQVPSLANRRP 260


>UniRef50_A4J6K3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Desulfotomaculum RepID=A4J6K3_DESRM
          Length = 277

 Score =  261 bits (668), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 63/274 (22%), Positives = 110/274 (40%), Gaps = 22/274 (8%)

Query: 2   LVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
            +A  Q   T    +KN       + +AA   A +   PE  +     +        Q +
Sbjct: 5   KIALVQMQATFGNIDKNLSTLEKFINEAAAQQAEIICFPEMCIQGYSREIPDF--LLQSI 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
           +GE +  L++ ++   +T I  +       R +   V ++ G  +  Y K HL       
Sbjct: 63  DGEAILFLKKLAQNKGITIIAGMAEKCLNKRPFITQVVIRPGQNIDYYRKTHL----GNS 118

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL-K 179
           E     AGNEI      E   +G+  C+D  FPE+    +L+GAE++  P A       +
Sbjct: 119 EQPYYQAGNEI-KTFSTEKTTIGIQICWDTHFPEMTTILSLRGAEVIFAPHASPTIVGDR 177

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAA-ASEMPALIM 233
           +  W   LAARA D + ++ A    G+        G S +IDP G  +A       ++++
Sbjct: 178 KAIWLKYLAARAYDNSVFLAACNLVGDDGNGRQFCGGSMVIDPKGNVLAEDFEGKQSMLV 237

Query: 234 AEVTPERVRQVRAQLP-------VLNNRRFAPPQ 260
            ++   ++  +R +          L NRR    +
Sbjct: 238 VDLDCAQINAIRERKSSSMANSFFLANRRPEIYK 271


>UniRef50_D2RHR5 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Archaeoglobus profundus DSM 5631
           RepID=D2RHR5_ARCPR
          Length = 231

 Score =  261 bits (667), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 58/252 (23%), Positives = 99/252 (39%), Gaps = 23/252 (9%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +   Q       +KN      L+ +   + A +   PE      + +           
Sbjct: 1   MRIGLAQLR-LENMDKNVRKALDLLRK---SKADVVVFPELFNTGYNLENISKSDP---- 52

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
                  L   SK      I  I         +N  + +  G I+ R+ K  L+    + 
Sbjct: 53  -----KFLIEASKETKAVIIAGIPEKG-----YNTALVIHRGKILGRHRKTKLFPL--LN 100

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           E +   AG ++   +E      G+M CY+LRFPE+A     +GA+IL + A +     + 
Sbjct: 101 EHKIFKAG-KVVKPIETPFGLFGIMICYELRFPEIARKLVNKGAKILFVIAQFPSE--RI 157

Query: 181 HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER 240
            HW  LL ARA++   ++V      +   G S ++DP G  +    +  A    ++  + 
Sbjct: 158 EHWKVLLRARAIENQVFVVGVNCVNDHCGGYSMVVDPLGNVLKELGDCEAYDEVDINIKY 217

Query: 241 VRQVRAQLPVLN 252
           V +VR + P LN
Sbjct: 218 VDEVRKKYPFLN 229


>UniRef50_Q0VS65 Carbon-nitrogen hydrolase family protein n=2 Tax=Alcanivorax
           RepID=Q0VS65_ALCBS
          Length = 285

 Score =  261 bits (667), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 81/274 (29%), Positives = 120/274 (43%), Gaps = 27/274 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           VAA Q       + N E  A L+ +A +  ASL  LPE        D        + LE 
Sbjct: 10  VAAIQMTSVESAKANLEQAAQLLQEAHDQGASLAVLPENFA-GYGVDYRALAAEYERLE- 67

Query: 63  EFLGRLRRESKRNMMTTILTIH--------VPSTPGRAWN-MLVALQAGNIVARYAKLHL 113
                L  ++ R  M  I             P    R     L     G +V RY KLHL
Sbjct: 68  ---QWLCEQASRLGMAIIGGSIPSLTRPDGEPVPAPRVRTRSLAVSSEGQVVGRYDKLHL 124

Query: 114 YDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +DA         +ES   + G  I     + G++VGL  CYDLRFP LA      GAE+L
Sbjct: 125 FDAQVHDAQGQYRESDFFEPGEAIVT-APLGGVQVGLAICYDLRFPALAQRLTSAGAELL 183

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTI 222
           V P+A+      + HW  LL A A+ T CY++ A +CG       + G S ++ P+G  +
Sbjct: 184 VYPSAFTA-VTGKAHWELLLRATAVQTGCYVLGANQCGQHSPRRASYGHSMLVSPWGDVV 242

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
           A+    P +++  +    + ++R ++PV  ++R 
Sbjct: 243 ASLGNAPGVLVTPLDLATLYELRQRMPVQQHQRL 276


>UniRef50_O59829 Probable nitrilase C965.09 n=2 Tax=cellular organisms
           RepID=YCU9_SCHPO
          Length = 272

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 63/274 (22%), Positives = 109/274 (39%), Gaps = 21/274 (7%)

Query: 1   ML--VAAGQFAVTS-VWEKNAEICASLMAQAAENDAS--LFALPEALLARDDHDADLSVK 55
           M   +A  Q A      + N +  +S + +  E++ S  L   PE + +  +     +  
Sbjct: 1   MKANIACVQMAPKVCDVKHNLQKMSSYVHEVMESNPSTNLILFPELITSGYECGNTFTQI 60

Query: 56  SAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTP--GRAWNMLVAL-QAGNIVARYAKLH 112
           +    EG     +   + +  +  I              +N  + + + GN+   Y K+H
Sbjct: 61  AEIAGEGPSFKTMSNLAAKYHVNIIYGFPEKEEKQSNIIYNSCIYITENGNLGGVYRKVH 120

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
           L+D     E +    G++  P+ E    K+G+M C+D  FPE+A   AL GA++LV+   
Sbjct: 121 LFDT----ERKHFKKGSD-FPIFETSFGKLGVMICWDTAFPEVARIHALNGADLLVVATN 175

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEM 228
           W      +  W  +  ARA +    +VAA   G        G S+II P G  I A  E 
Sbjct: 176 WENPYSDD--WDLVTKARAFENCIPLVAANRVGTDEKLSFFGHSKIIGPTGKVIKALDEE 233

Query: 229 -PALIMAEVTPERVRQVRAQ-LPVLNNRRFAPPQ 260
              +I   V  +  + +R        +R     +
Sbjct: 234 KEGVISYTVDLDDAKPLRKNYYTFFEDRMPDLYK 267


>UniRef50_Q972X1 264aa long hypothetical beta-ureidopropionase n=1 Tax=Sulfolobus
           tokodaii RepID=Q972X1_SULTO
          Length = 264

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 67/272 (24%), Positives = 115/272 (42%), Gaps = 19/272 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDH--DADLSVKSAQ 58
           M +A  Q  +T   + N E    L+ +A +N A + AL E                  A+
Sbjct: 1   MRIAIIQTYMTWDKKDNIERQVELVNKAIDNKAKIIALDELSNTIYFPFEQNPKYFSWAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
              GE L R +  SK   ++ I+ I    +    +N    L  G I+ +Y K HL     
Sbjct: 61  TERGETLQRFKEISKEREVSLIVPIFERDSN-FFYNTAFILDNGEIIGKYRKTHLPQEEF 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP--AAWVRG 176
             E      G+   P+ +++G+K G++ C+D  FPE    + ++GA ++ +P  AA+   
Sbjct: 120 FNEYYYFKVGDLGFPIFDLKGVKTGVVICHDRHFPEPVRVEVIKGAWLIFIPSVAAF--- 176

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECG-------NKNIGQSRIIDPFGVTIAAASEMP 229
              +  W   L A A+  T Y+      G        +  G+S II P G  +  A +  
Sbjct: 177 ---KEIWELELKAHAVFNTVYIAGINRFGKEYPNQKEEYFGESMIISPIGEIVTKAEKNE 233

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
            ++ A+++ + V   R + P L  +R +   L
Sbjct: 234 EILYADISEDEVINARIKRPFLK-KRLSSYGL 264


>UniRef50_A0PVY5 Amidohydrolase n=12 Tax=Actinomycetales RepID=A0PVY5_MYCUA
          Length = 280

 Score =  260 bits (665), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 86/270 (31%), Positives = 129/270 (47%), Gaps = 21/270 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q    +    N E+      +AA+  A L   PEA + R           AQ L
Sbjct: 1   MRIALAQILSGTDPTANLELVRDYAERAADAGARLVVFPEATMCRFGVP---LGPVAQPL 57

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG---NIVARYAKLHLYDAF 117
           +G +   +RR + +  +T +  +  P+  GR  N L A   G        Y K+HLYDAF
Sbjct: 58  DGPWANGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKIHLYDAF 117

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              ESR V  G+E   ++ V+  +VGL  CYD+RFP L    A +GAE++V+ A+W  GP
Sbjct: 118 GFAESRTVAPGHEPV-VITVDDFQVGLTVCYDIRFPALYTELARRGAELIVVSASWGSGP 176

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECG--------------NKNIGQSRIIDPFGVTIA 223
            K   W+ L  ARALD+  Y+ AAG+                 + +G S +  P G  +A
Sbjct: 177 GKLDQWTLLARARALDSASYVAAAGQADPGDTASDPGGGSGAPRGVGGSLVTSPLGEVVA 236

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNN 253
           +A   P L++A++   +V   R  + +L N
Sbjct: 237 SAGSDPQLVVADIDLAKVGAARDNIGMLRN 266


>UniRef50_B9JB81 Amidohydrolase protein n=4 Tax=cellular organisms
           RepID=B9JB81_AGRRK
          Length = 285

 Score =  259 bits (663), Expect = 7e-68,   Method: Composition-based stats.
 Identities = 75/268 (27%), Positives = 121/268 (45%), Gaps = 15/268 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              AA Q        KNA   A L+ +AA   A     PE   A       L        
Sbjct: 3   FKAAAIQMCSGVDPVKNAADMARLVREAAAQGAVYVQTPEMTGAVQKDRPGLRAVLRDEA 62

Query: 61  EGEFLGRLRRESKRNMMTTILTI-HVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYD--- 115
               +      +K   +   +    +P   G+  N        G +++RY K+H++D   
Sbjct: 63  NDIIVNTASDLAKELGIHVHVGSTAIPLDDGKIANRGFLFGPDGKLISRYDKIHMFDVDL 122

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES     G+E   ++ +   ++G   CYD+RFP+L  AQA+ GA+++ +PAA+
Sbjct: 123 DNGESWRESAVYRPGSEA-RIVSLPFAELGFSICYDVRFPQLFRAQAVAGAQVMTVPAAF 181

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGEC-----GNKNIGQSRIIDPFGVTIAAA-SE 227
            R    E HW  LL ARA++   +++AA +      G +  G S IIDP+G  +AAA   
Sbjct: 182 TRQT-GEAHWEILLRARAIENGMFVIAAAQAGKHEDGRETFGHSMIIDPWGKVLAAAGGT 240

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
             A+++AE+    V+    ++P L N R
Sbjct: 241 GEAVLVAEIDVAAVKSAHDKIPNLKNAR 268


>UniRef50_Q9Y9L1 Putative hydrolase n=1 Tax=Aeropyrum pernix RepID=Q9Y9L1_AERPE
          Length = 268

 Score =  259 bits (663), Expect = 8e-68,   Method: Composition-based stats.
 Identities = 81/265 (30%), Positives = 127/265 (47%), Gaps = 4/265 (1%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPE-ALLARDDHDADLSVKSAQL 59
           M +A  Q A T   + N E    L ++  +N   +   PE  +L       D    +A+ 
Sbjct: 1   MNIAVLQVASTREKDANLESVKRLASR-VKNSPDIVLTPEYLMLDPTGLGRDAIYDAAED 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFA 118
           LEG +   L + ++      +  + + +  GR  N  V   + G I+  Y K HL+DA+ 
Sbjct: 60  LEGRWSRELSKIAESLGSCLLGHLFLKTPSGRVANAAVLYSRDGGIIGVYRKTHLFDAYG 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQAL-QGAEILVLPAAWVRGP 177
             ES   + G+E+    +  G  +G+  CY+LRFPE+   Q+L  G +I ++PAAW RGP
Sbjct: 120 YVESSFTEPGDELWEPRKACGASIGVAICYELRFPEIFRTQSLVGGVDIFLVPAAWYRGP 179

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVT 237
            KE   S L  ARA + T Y+  A   G   +G+S II P G T+A A     ++  E+ 
Sbjct: 180 GKEEALSVLSRARAQENTSYVAVASNAGANFVGRSMIIHPLGYTLAQAPPWEWVLEHEID 239

Query: 238 PERVRQVRAQLPVLNNRRFAPPQLL 262
              + + R  LPVL + +    + L
Sbjct: 240 LREIERARKSLPVLEHVKPHLYRYL 264


>UniRef50_C7QIS9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=11 Tax=Actinomycetales RepID=C7QIS9_CATAD
          Length = 275

 Score =  259 bits (662), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 58/275 (21%), Positives = 112/275 (40%), Gaps = 20/275 (7%)

Query: 1   MLVAAGQF----------AVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA 50
           + +A  Q              +    N         +AAE+ A L   PE  L   +  A
Sbjct: 3   LRLACLQAPATDHPDGAPDPVADRRANLAALDDTARRAAESGARLLITPEMYLTGYNLGA 62

Query: 51  DLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYA 109
           ++    A+   G     +   + ++ +  +         G  +N + +    G   A Y 
Sbjct: 63  EVVAGLAEERFGPAQQEISAIAAKHGIAILYGYPERDGDGVVYNAVQLIGGDGASKANYR 122

Query: 110 KLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
           K HL+      +      G+E+    +++G++VG + CYD+ FPE   A A  G ++L++
Sbjct: 123 KTHLFGDV---DRAAFAPGSELVVQADLDGIRVGFLICYDVEFPEPVRAHADAGTQLLLV 179

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAA 225
           P A +R    E+    ++ ARA+++  ++      G +      G++R++ P G  +A  
Sbjct: 180 PTALMRPY--EYVPRQIVPARAIESQLFVAYVNRVGVERDFVYAGETRVVAPDGRELAVG 237

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
            +   L++A+V P  +   R     L +RR     
Sbjct: 238 GDHEELLLADVDPADLAASRDLNTYLQDRRTDLYG 272


>UniRef50_UPI0001973219 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Clostridium sp. M62/1 RepID=UPI0001973219
          Length = 262

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 60/268 (22%), Positives = 108/268 (40%), Gaps = 13/268 (4%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q  +     ++N E    L  +A      +  LPE              + +  
Sbjct: 1   MRVAMIQMDMELGRPDENFEKAVRLTEEACAARPDVITLPETWNVGFFP-RKNLEELSDR 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHV-PSTPGRAWNML-VALQAGNIVARYAKLHLYDAF 117
                       ++++ +  I          G  +N   V  + G + A+Y K+HL+   
Sbjct: 60  DCSRVRENFSMLARQHAVNIIAGTVANRKPDGGIYNTACVFDRKGELTAQYDKVHLFSPS 119

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              E      G+      E++G+   L  CYD+RFPEL  ++ L G+++  + A W    
Sbjct: 120 G--EHEFFRCGDRPCN-FELDGIPCSLAVCYDIRFPELIRSEMLAGSKVQFVVAQWPEA- 175

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIM 233
            +  HW TL  ARA+++  Y+      G     +  G S +  P G  +    E   +++
Sbjct: 176 -RRLHWDTLNRARAIESQSYVCCTNSVGTAGEVRCAGHSAVYGPMGECLILGGEKEQILV 234

Query: 234 AEVTPERVRQVRAQLPVLNNRRFAPPQL 261
           A++    V +VR+ + V ++RR    +L
Sbjct: 235 ADLELSEVDRVRSSINVYHDRRPEAYRL 262


>UniRef50_C6B8T0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM1325
           RepID=C6B8T0_RHILS
          Length = 287

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 75/271 (27%), Positives = 116/271 (42%), Gaps = 19/271 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q +       N    A LM +A      L  LPE         AD    + ++ 
Sbjct: 1   MKIALVQMSSQPDRAYNLAEAARLMREAMIGRPDLIVLPEHFDWLGGTVADKRRAADRIP 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPST--PGRAWNMLVALQ-AGNIVARYAKLHLY--- 114
            GE    ++R +K N +       +       R +N  V     G  V  Y K+HL+   
Sbjct: 61  GGEAYVLVQRFAKDNAVWVHAGSLMERRGQDHRVYNTTVVFNAKGEEVGLYRKIHLFDIT 120

Query: 115 --DAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
             D     ES  V  G ++  + E++G ++G   CYDLRF  L    A +  +I VLPAA
Sbjct: 121 APDGKTYSESAAVAPGRDLF-IYELDGHRIGCAICYDLRFSRLFDRLAEEKVDIFVLPAA 179

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECG---------NKNIGQSRIIDPFGVTIA 223
           +      + HW  L  ARA++   Y  A G+CG          +  G S + DP+G  +A
Sbjct: 180 FTYQT-GQAHWEVLCRARAIEFQAYFAACGQCGSYAMRDGELRRTFGHSMVCDPWGQIVA 238

Query: 224 AASEMPALIMAEVTPERVRQVRAQLPVLNNR 254
            A     +++ E+ P R+ +VR  +P+  +R
Sbjct: 239 RAENDVCVLVVEIDPARLPEVRRLIPMAEHR 269


>UniRef50_C8NJS3 Carbon-nitrogen hydrolase family protein n=16 Tax=Corynebacterium
           RepID=C8NJS3_COREF
          Length = 294

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 75/267 (28%), Positives = 120/267 (44%), Gaps = 20/267 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M +A  Q         N E+  +    AA   A L   PEA             + A+ L
Sbjct: 32  MRIALIQITSGGDKMANLELVRTTATDAAAQGARLLIYPEATSQAFGTGR--LDEQAEDL 89

Query: 61  -EGEFLGRLRRESKRNMMTTILTIHVPSTP--------GRAWNMLVALQAGNIVARYAKL 111
             G F   +++ ++   +  +  +  P+           R  N  +    G +   Y K+
Sbjct: 90  HTGAFATGVQQLAEDLGVVIVAGMFTPADTVEQDGKTLHRVHNTALVTGNG-LHEGYHKI 148

Query: 112 HLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
           + YDAF  +ES  V  GNE+  + +++G+KVG+  CYDLRFP      A  GAEI+V+P 
Sbjct: 149 NTYDAFGYRESDTVKPGNELH-VFDLDGVKVGVAICYDLRFPTQFQELARAGAEIIVVPT 207

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGEC-------GNKNIGQSRIIDPFGVTIAA 224
           +W  G  K      L  ARALD+T +++   +        G   IG S ++DP GV   +
Sbjct: 208 SWQDGEGKLEQLQVLTRARALDSTSWILMCDQARPTEKRKGPAGIGHSMVVDPTGVIADS 267

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVL 251
           A   P  ++A++    ++ +R  +PVL
Sbjct: 268 AGYEPETVIADIDLSNLQDIRKSIPVL 294


>UniRef50_Q8TLM7 Carbon-nitrogen hydrolase n=2 Tax=Methanosarcina RepID=Q8TLM7_METAC
          Length = 309

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 69/314 (21%), Positives = 115/314 (36%), Gaps = 63/314 (20%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q  V     ++N E    +  +A +  A L   PE       +  +    +A+ 
Sbjct: 1   MKVACIQMDVLQCKKQENLEKALYMALKAVKKGAELIVFPEVFTTGFCY--EDLNHAAES 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIH----------------------------------- 84
           L    L  L   S+ N    + +I                                    
Sbjct: 59  LPSPTLENLACFSEANDCIILGSIIQKDSGEAYTEDDGEGSNDKGRDGGKKGSKKEEKGF 118

Query: 85  --------------VPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQESRRVDAGNE 130
                                 +N+    ++G +   Y K H + A    E+     G+ 
Sbjct: 119 SGKETEIPGSKAFTERKNSTLYYNLGFCFESGVLAGTYLKTHPFKA----ENGYFSKGSS 174

Query: 131 IAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAA 189
           I P+ L+ + +K+GL  CY+LRFPE+A   ++ G+++LV  AA+     +  HW TL  A
Sbjct: 175 IEPISLKKQNLKIGLEICYELRFPEVARKLSIAGSDLLVTIAAFPNP--RAEHWKTLAKA 232

Query: 190 RALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVR 245
           RA++     +A    G+       G S IID +G   A A      I+ ++      ++R
Sbjct: 233 RAIENQIPHIACNRTGSVPDCTYFGNSMIIDAWGEIKAEAGSKECTIVCDLDLTGKEEIR 292

Query: 246 AQLPVLNNRRFAPP 259
             +PV  +RR    
Sbjct: 293 KAIPVFEDRRIELY 306


>UniRef50_C0VX65 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Corynebacterium glucuronolyticum
           RepID=C0VX65_9CORY
          Length = 257

 Score =  258 bits (660), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 73/258 (28%), Positives = 109/258 (42%), Gaps = 11/258 (4%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           M VA  Q   +   + N  +    +  AA   A L   PE         A     SA   
Sbjct: 1   MKVALCQINSSGDIDSNLALVEENVRTAAAEGARLIVFPE--ATMHAFGAGPLTGSAARF 58

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAIQ 120
            G F   ++       +  +     P    R +N  +  +       Y K HLYDAF   
Sbjct: 59  -GWFTTAIQSLVDDLSVAVVCGCFRPEEGERVYNTALIARPNEEPLLYDKTHLYDAFGFA 117

Query: 121 ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE 180
           ES  V  G  +    + EG+  G+  C+D+RFP L    A  GA+ +++P +W  G  K 
Sbjct: 118 ESDTVAPGENVVT-FDWEGITFGVAICFDIRFPALFKKMARAGAQAIIVPTSWTPGEQKV 176

Query: 181 HHWSTLLAARALDTTCYMVAAGEC----GNK---NIGQSRIIDPFGVTIAAASEMPALIM 233
           +HW  L  ARALD+  +++A  +     G      +G S +IDP G  +A   +   ++ 
Sbjct: 177 YHWRLLSRARALDSATFILATDQAFLDDGRTDPVGVGYSSVIDPLGQVVAELEQDEGILY 236

Query: 234 AEVTPERVRQVRAQLPVL 251
           AE+    V +VR  LPVL
Sbjct: 237 AELDTTAVEKVRQSLPVL 254


>UniRef50_C7GZE3 Nitrilase protein n=1 Tax=Eubacterium saphenum ATCC 49989
           RepID=C7GZE3_9FIRM
          Length = 268

 Score =  258 bits (660), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 55/264 (20%), Positives = 108/264 (40%), Gaps = 15/264 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             +   Q  V    + + E       +A +  A +  +PE       +        A+  
Sbjct: 2   FKLGLCQTKVYENKDDSIESVRKTALRAKDMGADVICIPEMWNTPYSN--RYIKNYAEGR 59

Query: 61  EGEFLGRLRRESKRNMMTTILTIHV-PSTPGRAWNMLVALQ-AGNIVARYAKLHLYD--- 115
           +G     ++  ++   +  +          G  +N        G+ +AR+ K+HL+D   
Sbjct: 60  DGGCYRFMKTLARDLGVYFVGGSIPFKDEKGDIYNTSFVFSKDGDEIARHDKIHLFDIDF 119

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
                +ES  +  G     +++ E  K+G+  C+D+RFPEL  A   +GA+++++P ++ 
Sbjct: 120 EDMHFKESLFLKNGTTA-TVVDTEFGKIGIGLCFDVRFPELFRAMTNRGAKLILVPGSFN 178

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMP 229
                  HW   L  RA+D   ++       ++N        S  +DP G+++    E  
Sbjct: 179 M-RTGPLHWENTLKQRAVDNQIFIAGCSPARDENAIYVSFANSMAVDPLGISLGNCGEEE 237

Query: 230 ALIMAEVTPERVRQVRAQLPVLNN 253
             I+ E+    V++ R  LP+L N
Sbjct: 238 GCIVEEIDFREVKRARNVLPILKN 261


>UniRef50_A8SQH9 Putative uncharacterized protein n=1 Tax=Coprococcus eutactus ATCC
           27759 RepID=A8SQH9_9FIRM
          Length = 314

 Score =  257 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 66/274 (24%), Positives = 112/274 (40%), Gaps = 19/274 (6%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHD--ADLSVKSA 57
              AA          + N +  A    +A+   A     PE            +   + +
Sbjct: 42  FKAAAVNMDCELGNVKANLKKMADFCKEASTKGALAICFPELATTGYSPTILGEKYYEIS 101

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPST-PGRAWNMLVALQA-GNIVARYAKLHLYD 115
           + + G     L + +K   +  +  I   S  PGR +N  +A+   G IV+ Y K+H++ 
Sbjct: 102 EPIPGPSTNYLCKVAKATGLYIVTGISEKSGVPGRLYNSQIAISPEGKIVSIYRKIHVWG 161

Query: 116 AF--AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
                 +ES   + G       ++   K G M CYD  FPE A   +L G+ ++   AAW
Sbjct: 162 LEKLTWRESITCEYGT-----FDMPMCKAGHMICYDTSFPETARVLSLMGSNVIFDSAAW 216

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMP 229
               L+   W     ARA++   +M+ +  CG +      G+SRII P G  +AAA    
Sbjct: 217 --RNLEADIWELNTRARAVENHVFMICSNRCGVEGDSTLNGESRIIGPRGNVLAAAGHEE 274

Query: 230 ALIMAEVTPER-VRQVRAQLPVLNNRRFAPPQLL 262
            +I A++  +  ++     L  + +RR     L+
Sbjct: 275 EIIYADIDIDSCIKDNAMMLSYMKDRRPEAYSLI 308


>UniRef50_C9N4S0 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=6 Tax=Streptomyces RepID=C9N4S0_9ACTO
          Length = 265

 Score =  257 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 76/266 (28%), Positives = 111/266 (41%), Gaps = 15/266 (5%)

Query: 1   MLVAAGQFAVTSVWEKN--AEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M  +  Q AV      N   E  ASL+  AA+  A L  LPE        D     + A+
Sbjct: 1   MHASLIQMAVNPDESVNSRRERAASLV--AAQRGADLVLLPELWPVG-AFDYTAFAEEAE 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIH-VPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA 116
            L+G     + + +    +          +  G  +N  +     G   A Y K+H +  
Sbjct: 58  PLQGPTHRIMAKAAAEAGVWLHAGSFVERAEDGTLYNTSLVFSPEGERAAAYRKIHRF-G 116

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
           F   E+  + AG E+  +  +    +GL TCYDLRFPE        GAE LV+ A W   
Sbjct: 117 FDKGEAVLMGAGEELVTVA-LPETILGLATCYDLRFPEQFRGLVDAGAETLVVSAGWPER 175

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKN----IGQSRIIDPFGVTIAAASEMPALI 232
             +  HW+ L  ARA++   Y++A G  G        G S ++DP+G  +A A     ++
Sbjct: 176 --RRSHWTLLAQARAVENQAYVLAVGSAGTHAGVEQAGHSIVVDPWGEVLAEAGAAEEVL 233

Query: 233 MAEVTPERVRQVRAQLPVLNNRRFAP 258
             E  P R    R Q P L +RR   
Sbjct: 234 TVEFDPARATTTREQFPALKDRRLGL 259


>UniRef50_B1L5H4 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=2 Tax=Archaea RepID=B1L5H4_KORCO
          Length = 265

 Score =  257 bits (658), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 60/273 (21%), Positives = 107/273 (39%), Gaps = 27/273 (9%)

Query: 2   LVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARD-DHDADLSVKSAQL 59
            V   Q        E N +    L   A++ ++ L   PE           + ++K ++ 
Sbjct: 3   RVGFVQTNPEFGAVESNLKRALDL---ASKVESDLLVFPELFNTGYLFLSREEALKLSEG 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
           L+G  + RL   +  +    +         G+ +N  VA+   G++   Y K HL+    
Sbjct: 60  LDGPTIKRLSDFASEHSTAIVAGFPER-DGGKVYNSAVAIDIDGDVKGVYRKTHLF---- 114

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +E    D G+    + ++ GM+VG+M C+D  FPE A + AL GA+I+  P+  V    
Sbjct: 115 YEEKLIFDPGDTGFRVFDLAGMRVGIMICFDWVFPESARSLALSGAQIIAHPSCLVMPYA 174

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK--------NIGQSRIIDPFGVTIAAASEM-P 229
            +         RA +   +++ +   G +          G S I DP    +  A E   
Sbjct: 175 PKAD-----PVRAFENRVFIILSDRSGVEERGGKKLRYHGMSLISDPKMNILTQAPEEGE 229

Query: 230 ALIMAEVTPERVRQVR--AQLPVLNNRRFAPPQ 260
            + +AE+ P+     R      +  +RR     
Sbjct: 230 HVGIAEIDPKLAEDKRVNELNDIFLDRRPEFYG 262


>UniRef50_Q5UF08 Predicted amidohydrolase n=1 Tax=uncultured alpha proteobacterium
           EBAC2C11 RepID=Q5UF08_9PROT
          Length = 276

 Score =  257 bits (658), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 74/265 (27%), Positives = 115/265 (43%), Gaps = 16/265 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + VAA Q+  +    K       L+A+AA   ASL ALPE           L  K+    
Sbjct: 2   LRVAALQYCASDDVAKTLHHIQPLIAEAASK-ASLVALPECANYLAASREQLFQKAEWDD 60

Query: 61  EGEFLGRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVAL-QAGNIVARYAKLHLYD-- 115
           E      L   ++   +  +    +       +  N  +     G ++A Y K+H++D  
Sbjct: 61  ESYSQKWLGNIAREFGIWLLAGSLIMRRRDNNQLANRSLLFGPDGEVIAYYDKIHMFDAD 120

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES    AG     +  ++ +  GL  CYD+RF  L    AL GA++ ++PAA
Sbjct: 121 VGDGKMYRESASFSAGQSPV-IAHIDNVPCGLTICYDVRFAHLYRQLALDGAQLFLVPAA 179

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           +     K  HW  LL ARA++T CY+VA  + G         G S II+P+G  IA A +
Sbjct: 180 FTALSGK-AHWHVLLRARAIETGCYIVAPAQSGTHADGRKTYGHSLIINPWGEIIAEAKD 238

Query: 228 MPALIMAEVTPERVRQVRAQLPVLN 252
             ++I A +      + R  +P L 
Sbjct: 239 GDSIIYAALDLSATARARNAIPSLK 263


>UniRef50_B2HTJ8 Predicted amidohydrolase n=18 Tax=Acinetobacter RepID=B2HTJ8_ACIBC
          Length = 274

 Score =  257 bits (657), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 75/277 (27%), Positives = 115/277 (41%), Gaps = 26/277 (9%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           V+  Q       E N ++  SL+ Q+   +ASL   PE  +      A    ++A+  E 
Sbjct: 4   VSVVQMNSQDDIESNFQVIESLIQQSKAQNASLIVFPENFVC---FAAGKQRETAEQFES 60

Query: 63  EFLGRLRRESKRNMMTTILTI----HVPST----PGRAWNMLVALQAGNIVARYAKLHLY 114
               RL + + +  +  +         P       GR   + + +      ARY K+HL+
Sbjct: 61  -IQQRLEKLAHQYQIWIVAGTLPCPFRPDGSIIQDGRVRTVSLCISPERTEARYDKIHLF 119

Query: 115 DA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILV 168
           D          QESR  + G +   +       +GLM CYDLRFPELAL    QGA +L 
Sbjct: 120 DVQVGDAVGGYQESRFFEPGTD-VVVTSTPFGNIGLMVCYDLRFPELALTLRQQGAHLLT 178

Query: 169 LPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIA 223
            PAA+      + HW  LL ARA+D+ CY++ A + G         G +   D  G  ++
Sbjct: 179 APAAFTY-TTGQMHWQLLLQARAMDSQCYVLGAAQQGWHGEKRQTWGHAGATDSRGQVLS 237

Query: 224 AAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
               E   LI           VR  +P++ +R+    
Sbjct: 238 MIGYEGNGLITVPFDLAAQELVRTSMPLMMHRKLIHY 274


>UniRef50_B1MI91 Hypothetical carbon-nitrogen hydrolase family protein n=1
           Tax=Mycobacterium abscessus ATCC 19977
           RepID=B1MI91_MYCA9
          Length = 266

 Score =  257 bits (657), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 11/260 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q +  +   + N    A     AA  DA L   PE  L   +         AQ 
Sbjct: 5   LRLAVVQCSSQAADVQANLARLAETAHAAAAGDAQLVVFPEMYLTGYNIGEWDIRDLAQS 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFA 118
            +G  +  +R+ +    M   +     ++ G+ +N  +     G +V  Y K HL+    
Sbjct: 65  PDGPAMQFIRQTACDADMHICVGYPERASDGQIYNSALICDPRGRVVLNYRKSHLFGDT- 123

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             E           PL  V G+ VGL+ CYD+ FPE   A A+  A+++V+P A +    
Sbjct: 124 --ERNVFTRPGPQLPLAVVHGVSVGLLICYDVEFPENVRALAMARADVVVVPTANMEPFH 181

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
                 T++ ARA +   Y+  A  CGN       G S I+ P G  +A A E   L++A
Sbjct: 182 --AVCETVVPARAYENQLYVAYANYCGNHDGLAYCGGSSIVGPDGTALARAGEGVGLLVA 239

Query: 235 EVTPERVRQVRAQLPVLNNR 254
           +V    + + R++   L +R
Sbjct: 240 DVDRAVIDRTRSRHCFLEDR 259


>UniRef50_Q2RWF2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=4 Tax=Rhodospirillaceae RepID=Q2RWF2_RHORT
          Length = 279

 Score =  257 bits (657), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 75/267 (28%), Positives = 122/267 (45%), Gaps = 14/267 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              A  Q         N E  ++L+ +A E  A +  +PE +   +    ++  K+    
Sbjct: 8   FTAACIQVNAGREVYPNVEAASALVREARERGADMVFMPENVAMMEWGRRNIQAKAMPEE 67

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNMLVALQ-AGNIVARYAKLHLYD--- 115
           +   L   R  ++   +         +   G   N    +   G I  RY K+H++D   
Sbjct: 68  DHVALTAFRDLARDLHIWLHCGTLAVAVGDGMVANRTYVVDSDGAIRGRYDKIHMFDVNL 127

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES    AG+    L ++   ++GL  CYDLRFP L  A A  G   L +PAA+
Sbjct: 128 ADGESYKESSTFQAGSRAVAL-DIPFGRLGLSICYDLRFPHLFRALAKAGCHYLTIPAAF 186

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEM 228
            R    E HW  L   RA++T CY+++  + G         G + IIDP+G  +A A E 
Sbjct: 187 TR-TTGEAHWHVLQRTRAIETGCYVISPAQTGTHAEGRQTYGHALIIDPWGRVLADAGEA 245

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRR 255
           P +I+A++ PE+V + RA +P L++ R
Sbjct: 246 PGIILAKIDPEKVVEARAMVPSLSHDR 272


>UniRef50_P55176 UPF0012 hydrolase in pqqF 5'region n=22 Tax=Bacteria
           RepID=YPQQ_PSEFL
          Length = 285

 Score =  256 bits (656), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 70/266 (26%), Positives = 114/266 (42%), Gaps = 13/266 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M VA  Q          N +    +  +A +  A L  LPE  L+  +   +     A+ 
Sbjct: 22  MRVALYQCPPRPLDVAGNLQRLHQVAMEATD--ADLLVLPEMFLSGYNIGLEAVGALAEA 79

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
            +G    R+   ++      +      S  G+ +N +  +   G  +  Y K HL+    
Sbjct: 80  QDGPSAQRIAAIAQAAGTAILYGYPERSVDGQIYNAVQLIDAQGQRLCNYRKTHLFGDL- 138

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
             +     AG +  PL+E++G K+G + CYD+ FPE A   AL GAE++++P A +    
Sbjct: 139 --DHSMFSAGEDDFPLVELDGWKLGFLICYDIEFPENARRLALAGAELILVPTANMIPYD 196

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMA 234
                   + ARA +  CY+  A  CG++      GQS I  P G  IA A    ALI+ 
Sbjct: 197 FVA--DVTIRARAFENQCYVAYANYCGHEEQIRYCGQSSIAAPDGSRIALAGLDEALIIG 254

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
            +  + + + RA    L++RR     
Sbjct: 255 TLDRQLMGESRALNRYLSDRRPELYD 280


>UniRef50_C5BHY1 N-carbamoylputrescine amidase n=3 Tax=Bacteria RepID=C5BHY1_TERTT
          Length = 305

 Score =  256 bits (656), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 58/290 (20%), Positives = 100/290 (34%), Gaps = 30/290 (10%)

Query: 1   MLVAAGQFAVTSV-WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLS--VKSA 57
           +  A  Q A+      +N  I    +  AAE  A L  L E    +     + +     A
Sbjct: 5   ITAAVIQQAIPGNSKTENLAITCDYIRDAAEQGAELVVLQELHATQYFCQVEDTGNFDLA 64

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNML-VALQAGNIVARYAKLHLYDA 116
           + ++G     +   +    +  +++       G   N   V          + K+H+ D 
Sbjct: 65  EDIDGPTAEIVADIAAELDIVIVMSGFERRAAGLYHNTAQVFDGERGRAGIFRKMHIPDD 124

Query: 117 FAIQESRRVDAGN------EIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
               E      G+           ++    K+G++ C+D  +PE A   AL GA++L+ P
Sbjct: 125 PGFYEKFYFTPGDGNTDSLNGFRPVQTRLGKLGVLVCWDQWYPEAARLMALAGADMLIYP 184

Query: 171 AAWVRGPLK--------EHHWSTLLAARALDTTCYMVAAGEC-----------GNKNIGQ 211
            A    P             W T+  + A+     ++ A              G +  G 
Sbjct: 185 TAIGWDPNDDEDEQARQRDSWITIQRSHAIANGLPVLVANRTGFEASPSTSDDGIEFWGS 244

Query: 212 SRIIDPFGVTIAAAS-EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           S I  P G  + A + E      AEV+ +R   VR   P + +RR     
Sbjct: 245 SFIAGPQGEFLLAPNIEAQGAFCAEVSLQRSESVRRIWPFMRDRRVDAYG 294


>UniRef50_A0BLB1 Chromosome undetermined scaffold_114, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0BLB1_PARTE
          Length = 284

 Score =  256 bits (656), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 68/277 (24%), Positives = 115/277 (41%), Gaps = 22/277 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  Q AV    +K  E  A+ +    + +  +  L E        + +   K+A+   
Sbjct: 8   KVALIQNAVFETKQKILEGVAASIRDCVQKECKVIFLGEFFNTIF--ETNQLKKNAEDFS 65

Query: 62  G----EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYD-- 115
                E    +++ S+   +  I  +   +  G+ +N  +A   G +V +Y K HL+D  
Sbjct: 66  DKNNRETYELMKQLSEEFQIMIIGGLPEVA-DGKLFNAALAFNDGKLVGQYRKCHLFDVD 124

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                   ES    +GN+   + + +  + GL  CYD+RFP  +     QG ++L  P+A
Sbjct: 125 IPGGITHFESNTFGSGNDYC-IFDSQYGRYGLGICYDIRFPIYSQVMRDQGCQVLSFPSA 183

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN--------KNIGQSRIIDPFGVTIAA 224
           +        HW  L  +RALD   Y+ +A             +  G S I DP G  +A 
Sbjct: 184 FN-QTTGPLHWELLNRSRALDNQVYVASAQAARYYSDDPDYYQTWGHSIITDPMGRVLAT 242

Query: 225 ASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
               PA+++ E+    V QVR  +P    +R    Q+
Sbjct: 243 CESDPAVLIQEINLSLVDQVRKNIPTSVQKRTDLYQV 279


>UniRef50_C5BSY0 Hydrolase, carbon-nitrogen family n=1 Tax=Teredinibacter turnerae
           T7901 RepID=C5BSY0_TERTT
          Length = 302

 Score =  256 bits (656), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 71/304 (23%), Positives = 116/304 (38%), Gaps = 55/304 (18%)

Query: 1   MLVAAGQFAVTSV-WEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
             V   Q        E N      L+ +A++ +  L  LPE LL           +  Q 
Sbjct: 5   FRVGLCQMVSQLEGVETNFSTLEGLLGRASKANCQLAVLPENLLTFGLKTRFTRDEQVQ- 63

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVP--------------------------STPGRAW 93
               +L R    ++ + +  +                                S   + +
Sbjct: 64  ----WLVRFSALARAHKLWLVAGSMPLHGFSWADGDGDGDWEVSADTIRWHDASEDVKPF 119

Query: 94  NMLVALQA-GNIVARYAKLHLYDA------FAIQESRRVDAGNEIAPLLEVEGMKVGLMT 146
              V     G I + Y K+HL+DA       A +ES     G+ +  + E    ++G+  
Sbjct: 120 ATCVVFDDQGRIASAYRKMHLFDADVKDNTGAYRESDSFARGD-MPVVCETPWGRMGVGI 178

Query: 147 CYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN 206
           CYDLRFPE   A   QGA+ +VLP+A+     K  HW  LL ARA++    M+   + G 
Sbjct: 179 CYDLRFPEYFRALRQQGADFVVLPSAFTWATGKV-HWELLLRARAVENQIVMIGVNQGGE 237

Query: 207 K-----NIGQSRIIDPFGVTIAAASE---------MPALIMAEVTPERVRQVRAQLPVLN 252
                   G S +++ +G  IA A +            L++ +V  + +  +R  +PV N
Sbjct: 238 HTPQRKTWGDSMVVNGWGEIIARAGDDKLLEDSQLGEHLVVTQVDLDELELLRKDMPVWN 297

Query: 253 NRRF 256
           +RR 
Sbjct: 298 HRRL 301


>UniRef50_D2RK67 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Acidaminococcus fermentans DSM 20731
           RepID=D2RK67_ACIFE
          Length = 254

 Score =  256 bits (655), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 65/261 (24%), Positives = 113/261 (43%), Gaps = 16/261 (6%)

Query: 1   MLVAAGQFAVTS--VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M V+  QF        + N       +    E+  SL  LPE       +  +      +
Sbjct: 1   MKVSVIQFERNEKYDVDANIAQMEQQIDLCKES--SLIVLPEMWATGY-YCFERYHHIEE 57

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAF 117
               + +  L R++K           +     + +N L  +   G  +A Y K +L    
Sbjct: 58  --NNKIIDFLCRKAKETGAYIAGGTIIEKIEDQYYNSLPFISPEGKCIATYRKRNLVTFN 115

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
           + +E + +  G E + +++    ++G   CYD+RFP+  +    +  +I+VL AAW    
Sbjct: 116 S-EEVKLIQNGKE-STVVDTPFGRIGFAICYDVRFPKNFIEMTEKNVDIIVLSAAW--SF 171

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIM 233
            +  HW  L   RA++   Y++A    G +      G S I DP+G  IAAA     ++ 
Sbjct: 172 PRLEHWCLLSQCRAIENVSYLLACNCVGTERGNVYFGHSAIYDPWGTKIAAAGIEKTIVS 231

Query: 234 AEVTPERVRQVRAQLPVLNNR 254
           AE+ PE V+++R + PVL +R
Sbjct: 232 AEINPEHVQEIRKKFPVLRDR 252


>UniRef50_P47016 Probable hydrolase NIT2 n=9 Tax=Saccharomycetaceae RepID=NIT2_YEAST
          Length = 307

 Score =  256 bits (655), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 84/304 (27%), Positives = 136/304 (44%), Gaps = 48/304 (15%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            VA  Q   ++   KN ++   L+++A +  A +  LPEA          L  +      
Sbjct: 7   RVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASD--YLSQNPLHSRYLAQKS 64

Query: 62  GEFLGRLR----RESKRN--MMTTILTIHVP-------STPGRAWNMLVALQ-AGNIVAR 107
            +F+ +L+       + N   +   + +H+P           R  N+L+ +   G I+  
Sbjct: 65  PKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQE 124

Query: 108 YAKLHLYD-----AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQ 162
           Y KLHL+D        ++ES+ V  G  I  ++E    K+G   CYD+RFPE +L     
Sbjct: 125 YQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSM 184

Query: 163 GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECG----------------- 205
           GAEIL  P+A+      E HW  L  ARA+DT CY++  G+ G                 
Sbjct: 185 GAEILCFPSAFTI-KTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSA 243

Query: 206 ------NKNIGQSRIIDPFGVTIAAASE---MPALIMAEVTPERVRQVRAQLPVLNNRRF 256
                  ++ G S +IDP+G  IA A      P LI+A++  E ++++R ++P+ N RR 
Sbjct: 244 LEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRD 303

Query: 257 APPQ 260
               
Sbjct: 304 DLFH 307


>UniRef50_D1UMG3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Burkholderia sp. CCGE1001 RepID=D1UMG3_9BURK
          Length = 319

 Score =  256 bits (655), Expect = 6e-67,   Method: Composition-based stats.
 Identities = 66/274 (24%), Positives = 107/274 (39%), Gaps = 21/274 (7%)

Query: 3   VAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDH-DADLSVKSAQ-L 59
           +A  Q          N       +  AA   ASL  LPE         D + +   A+ L
Sbjct: 39  IACVQMEPHIGAKRANVARLIRHVETAASQGASLVVLPELATTGYVFADREEAFSLAEGL 98

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
            +GE        ++R  +  +  I   +   R +N  +       +  Y KLHL++    
Sbjct: 99  PDGETSELFADTAQRLGVHIVTGIAERAGK-RLYNSALITGPSGHIGIYRKLHLWN---- 153

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV----R 175
            E+R  + G+   P+      ++ +  CYD  FPE     A+QGA+I+ +P  WV    +
Sbjct: 154 NENRFFEPGDRGVPVFGTPLGRIAIAICYDGWFPETYRLAAMQGADIVCVPTNWVPMPSQ 213

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIA--AASEMP 229
              +    +TL  A A      +  A   G +     IGQS I+   G  +A  A+ +  
Sbjct: 214 PEDRSAMAATLTMAAAHSNGMAIACANRIGTERGQRFIGQSLIVGGDGWPLAGPASIDRE 273

Query: 230 ALIMAEVTPERVRQVR---AQLPVLNNRRFAPPQ 260
            ++ A +  +R R  R   A   VL +RR     
Sbjct: 274 EVLYATIDVKRTRAGRTLNAFNHVLRDRRADVYD 307


>UniRef50_C0F0M8 Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM
           3353 RepID=C0F0M8_9FIRM
          Length = 273

 Score =  256 bits (654), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 64/273 (23%), Positives = 110/273 (40%), Gaps = 24/273 (8%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +   Q  ++    E N E       +A EN       PE  L     + + + + ++ 
Sbjct: 1   MRIGMAQMDISWENIEDNKEKVEQFFKKAEENQVDCLVFPEMTLTGFSMNVEETGEKSEN 60

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGR---------AWNMLVALQAGNIVARYAK 110
            +          SK+  + T+     P    R          +N L   + G +   YAK
Sbjct: 61  QKH----FFEEMSKKYKILTVFGYTEPVPEERLKEHPNWNHYYNRLGIAENGELKLNYAK 116

Query: 111 LHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLP 170
           +H +      E      G ++  + E +G  +G   CYDLRFPE+    + + +EI+ + 
Sbjct: 117 IHPFSYG--FEGEYYQGGRKLKSV-EWKGTTLGAFVCYDLRFPEIFQISSEK-SEIIFVI 172

Query: 171 AAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAAS 226
           A W +   +   W TLL ARA++   +MV     G        G S I  P G  +    
Sbjct: 173 ANWPKS--RIDQWDTLLKARAIENQVFMVGVNRTGEGDGLHYNGHSAIYSPNGEAVTTIR 230

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
           E   L++ ++ PE ++++R   P+ N+RR    
Sbjct: 231 EEECLLIGDINPEEIKEMRKTFPMKNDRREELY 263


>UniRef50_Q3IFH8 Putative hydrolase, carbon-nitrogen family n=3 Tax=Alteromonadales
           RepID=Q3IFH8_PSEHT
          Length = 275

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 73/270 (27%), Positives = 126/270 (46%), Gaps = 21/270 (7%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALL--ARDDHDADLSVKSAQL 59
            + A Q       E+N +   + + Q       L  LPEA L  ++  +D     K A+ 
Sbjct: 7   TIIALQMCSGVDPEQNIQTLVNQLQQLPTTRPLLVCLPEAFLVFSKSGNDTLKVAKQAE- 65

Query: 60  LEGEFLGRLRRESKRNMMTTILT-IHVPSTPGRAWN-MLVALQAGNIVARYAKLHLYDAF 117
               +  +L    + + +      +  P    + +    +    G +VA Y K+HL+D  
Sbjct: 66  ---RYKQQLSELCQLHNIWLSAGTMPEPYNDNKYYAASHLFNAQGELVASYNKMHLFDVT 122

Query: 118 ------AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                 + +ES    AGNE   +++    K+GL  CYDLRF  L      QGAE++++P+
Sbjct: 123 VDDSTASYRESDFTQAGNE-VVVVDSPFGKIGLTVCYDLRFSALYTQLVRQGAEVILVPS 181

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAAS 226
           A+      + HW  LLAARA++T CY++AA + G         G S I+ P+G T++   
Sbjct: 182 AFTV-VTGQAHWQPLLAARAIETQCYVIAAAQYGAHENGRQTYGHSIILSPWGNTLSELP 240

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
                I A +  +++ ++R  +PV +++RF
Sbjct: 241 TGTGFISATLDLKQLHKIRRDMPVQSHQRF 270


>UniRef50_D0RND5 Hydrolase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RND5_9RICK
          Length = 265

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 67/260 (25%), Positives = 121/260 (46%), Gaps = 13/260 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              A  Q       ++N +    L  QA ++ A +   PE        +  L  KS    
Sbjct: 3   FNAACLQLTSNDQPKENLDQVIKLSDQAVKDGAQIILTPENTFLLTLDEGVLKEKSEDYE 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYD---- 115
           +G  +  + + +K N +  ++           +N  V +   G IV  Y K+H++D    
Sbjct: 63  KGFCINEIVKYAKSNSIWFLIGGTPVKENNNIFNRSVLISPKGEIVTTYDKIHMFDVNLP 122

Query: 116 -AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
              + +ES++  AG  +  + ++    +GL  CYDLRFP        +GA+ L +P+A+ 
Sbjct: 123 NGESYEESKKFKAGESL-SVTKLPWGNLGLSICYDLRFPNHYRQLMKKGADFLAVPSAFT 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMP 229
           +    E HW  LL +RA++  CY++A  + G         G S I+ P GV ++   E  
Sbjct: 182 KNT-GERHWHILLRSRAIENFCYVLAPAQTGKHFNNRETYGHSMIVSPDGVVLSEKKEDI 240

Query: 230 ALIMAEVTPERVRQVRAQLP 249
            LI++E+  E+V+++R+++P
Sbjct: 241 GLIISEIDIEKVKKIRSEIP 260


>UniRef50_A6CCB9 Predicted amidohydrolase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CCB9_9PLAN
          Length = 282

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 61/274 (22%), Positives = 105/274 (38%), Gaps = 20/274 (7%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDA-DLSVKSAQ 58
           M +A  Q  ++    E N       + + A   ASL   PE  L      + + ++  A+
Sbjct: 1   MKIAGVQMDISLMDKEGNLSRIIEKIKETAAAGASLTVFPECALTGYCFASLEEALPYAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
            + G    RL+   +    + ++ +   +  G  +N  V +    ++  Y K+HL     
Sbjct: 61  SIPGPSTDRLQEICRELNHSVVVGMLEQAEQG-VYNAAVLITPEGVLGSYRKIHLPYLGV 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
               R    G+    +       +GL  CYD  FPE +    ++GA+++VLP  W  G  
Sbjct: 120 ---DRFATPGDRDFAVYSHPEANIGLNICYDSAFPESSRIMTIEGADLIVLPTNWPTGAN 176

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAA-SEMPALIM 233
                   +  R+++   Y  A    G     + IG+SRI    G TIA +    P ++ 
Sbjct: 177 HVA--EHAINTRSMENGIYYCAINRIGAERGFEFIGKSRITGTAGETIATSTGTDPEILY 234

Query: 234 AEVTPERVRQVR-------AQLPVLNNRRFAPPQ 260
           A + P   R  R         +  L +RR     
Sbjct: 235 AIIDPALARNKRVDRVPDKHVIHRLADRRPELYG 268


>UniRef50_A7I462 Hydrolase in agr operon (ORF 5) n=1 Tax=Campylobacter hominis ATCC
           BAA-381 RepID=A7I462_CAMHC
          Length = 256

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 62/262 (23%), Positives = 101/262 (38%), Gaps = 11/262 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M ++  QF+      EKN E   + M  A      +  LPE         +    K A  
Sbjct: 1   MKISMIQFSSVKFQIEKNYEKVLNFMQDAISKKTDIIVLPELFDTGFFP-SKNLEKFADK 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
                       ++ N +  +          + +N        G I+A Y K+HL+    
Sbjct: 60  NAFRAREIFSNFARENCVNIVAGSICEMRNDKLFNASYIFDKNGKIIANYDKIHLFSTGN 119

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +ES     G +I     +  +  G+M CYDLRF E+A   AL+G  +L + A W    +
Sbjct: 120 EKESEIFTPGEKIIS-FRLNEIPCGIMICYDLRFAEIAKILALRGISVLFVVAQWPLKRI 178

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           K  H+  L  ARA++   ++ A         G S +I+P G  I        +   E+  
Sbjct: 179 K--HFEILAKARAIENEFFVCALN-----GFGNSILINPNGDEILKFDLNEGVKTVEINL 231

Query: 239 ERVRQVRAQLPVLNNRRFAPPQ 260
           + + Q R  L V  +R+    +
Sbjct: 232 DEIMQARDFLHVFEDRKPEIYK 253


>UniRef50_A6UC57 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Rhizobiaceae RepID=A6UC57_SINMW
          Length = 258

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 64/259 (24%), Positives = 99/259 (38%), Gaps = 11/259 (4%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M +A  Q   T      N          A+   A+L   PE  +       +  V+ A+ 
Sbjct: 1   MKLAVLQMKSTGGDVAANLARIGRAAIDASGKGATLLVAPELAITGYGAG-EAIVELAEP 59

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
            +G  +  LRR S++     I       +    +N  V +        Y K HLY  +  
Sbjct: 60  PDGPIVQELRRISRQTGTAIIAGFAE-QSGHTVYNSAVHVDGDTAPTVYRKSHLYGDY-- 116

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E            L E  G+  G++ CYD+ FPE     AL GA+ +++P A   G   
Sbjct: 117 -ERSLFSPAEPSTRLFEHRGVTCGMLICYDVEFPENVRRLALAGADAVLVPTALPAGWSG 175

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAAS-EMPALIMA 234
                 ++  RA +   ++  A  CG+       G SRI  P G  +A +      LI A
Sbjct: 176 TFIAEHMIQTRAFENQVFVAYANHCGSDDMFSFAGMSRIASPDGQVMAKSGSTDETLIFA 235

Query: 235 EVTPERVRQVRAQLPVLNN 253
           E+ P+     RA+   LN+
Sbjct: 236 EIDPQAFAISRAENTYLND 254


>UniRef50_B7CB92 Putative uncharacterized protein n=1 Tax=Eubacterium biforme DSM
           3989 RepID=B7CB92_9FIRM
          Length = 262

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 64/264 (24%), Positives = 110/264 (41%), Gaps = 24/264 (9%)

Query: 7   QFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLG 66
           Q +V+   ++N     ++       D  +  LPE       +DA   +K+A L   E L 
Sbjct: 3   QMSVSMDNQQNIAKLKNI------PDCDILVLPEMWNCPYHNDA---LKTAYLRHDESLE 53

Query: 67  RLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLY---DAFAIQES 122
            L+  ++ N +  +      +     +N    L   G+IV  Y K HL+   +     E+
Sbjct: 54  ALKETARTNKIWIVAGSICTNK----YNRCYILNSDGDIVCSYDKTHLFEFHNKQDYCEN 109

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
                GN +    +    K G++ CYD+RFPE++   A  GA+IL  PAA+     K+ H
Sbjct: 110 EVFVPGNHL-QCFDTPWGKCGILLCYDIRFPEVSRILAQNGAQILFCPAAFNEQATKK-H 167

Query: 183 WSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDPFGVTIAAASEMPALIMAEVT 237
           W      RAL+   ++                G S ++D FG  +    E  A  + ++ 
Sbjct: 168 WKLFTQTRALENEVFLCGVAPAKYTYKNYTSGGHSILVDGFGNIVVELGEEEACKVVDIH 227

Query: 238 PERVRQVRAQLPVLNNRRFAPPQL 261
            + + +VR ++P    RR    +L
Sbjct: 228 LKDIEKVRKRMPYWKVRRNDLYEL 251


>UniRef50_Q89413 A78R protein n=7 Tax=root RepID=Q89413_PBCV1
          Length = 298

 Score =  255 bits (652), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 58/289 (20%), Positives = 97/289 (33%), Gaps = 30/289 (10%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQ 58
           + +A  QFA T     N E    L+  AA N A +  L E    +      +    K A 
Sbjct: 5   VTIATTQFACTHDIFGNIERAEMLVRNAAANGAQVIVLQELFATKYFCQTQSPQYFKFAD 64

Query: 59  LLEGE-FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAF 117
             +    +    + +K   +   +            ++ VA   G+IV  Y K H+  + 
Sbjct: 65  PADDSVIVEIFSKLAKELGVVIPIPFFEKDGNNYYNSVAVADADGSIVGVYRKTHIPQSK 124

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
             +E       +    + E +  K+G++ C+D  F E A   AL+GA+ +V P A    P
Sbjct: 125 CYEEKFYFTPSSNPYEVFETKFGKMGVLICWDQWFSEAAKCLALEGADFIVYPTAIGSEP 184

Query: 178 -----LKEHHWSTLLAARALDTTCYMVAAGECGNK--------NIGQSRIIDPFGVTIAA 224
                    HW+  +   A  T   ++ A   G +          G S I D  G  +  
Sbjct: 185 EFPNGESYLHWARTITGHAAATGVPVIVANRVGRERFGKTKIDFFGGSFIADGTGAVVTQ 244

Query: 225 ASEMP--------------ALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
              +P                       + +   RA   +  +RR    
Sbjct: 245 VGGVPQKNGGVDPEPVDLKGYTKYTFDLDALENHRAFWGLYRDRRPELY 293


>UniRef50_C7QHA6 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QHA6_CATAD
          Length = 264

 Score =  255 bits (652), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 73/268 (27%), Positives = 113/268 (42%), Gaps = 17/268 (6%)

Query: 1   MLVAAGQFAV--TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQ 58
           M V+  Q AV      E        L+    E  A L  LPE  +         +  +  
Sbjct: 1   MRVSLMQLAVDDAEAPEDRWTRVVKLVEAERETGAELVVLPELWVTGGFDYKSWTGHAEP 60

Query: 59  LLEGEFLGRLRRESKRNM-----MTTILTIH-VPSTPGRAWNMLVALQAGNIVARYAKLH 112
           + + + +  L +  + +      M      +   +  G  +N  V        A+Y K+H
Sbjct: 61  IADSQPIAALEKV-RTHDGSGPEMWLHFGSYVERTPEGILYNTAVFRGPDGKQAQYRKIH 119

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
            +  F+  E   +  G +I  +       +GL TCYDLRFPEL      QG E +V+ +A
Sbjct: 120 RF-GFSEGEVTLMGPGKDIVTV-SSPWGTLGLATCYDLRFPELFRRLLNQGMEHMVMCSA 177

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEM 228
           W     +  HW  LL ARA++   ++ A    G        G+S +IDP+G  +A A   
Sbjct: 178 WPAK--RIEHWRVLLKARAIENQVFVFATNCVGTNGGVALGGRSAVIDPWGNVVAEAGTG 235

Query: 229 PALIMAEVTPERVRQVRAQLPVLNNRRF 256
             ++  +V P  V Q R+ LPVLN+RR 
Sbjct: 236 EEVLRVDVDPALVAQTRSALPVLNDRRL 263


>UniRef50_A6UCF8 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Rhizobiales RepID=A6UCF8_SINMW
          Length = 285

 Score =  255 bits (652), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 78/268 (29%), Positives = 116/268 (43%), Gaps = 15/268 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
              AA Q        +NAE  A L+ +AA   A     PE   A     + L        
Sbjct: 3   FKAAAVQMCSGVDPARNAETMAELVREAALRGAGYVQTPEMTGAIQRDRSGLRSILRDEA 62

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPS-TPGRAWNMLVAL-QAGNIVARYAKLHLYD--- 115
               + +  R +    +   +     +   G+  N        G  +  Y K+H++D   
Sbjct: 63  NDIVVRKAARLAGELAIYLHVGSTPIALADGKIANRGFLFGPDGAKICEYDKIHMFDVDL 122

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
               + +ES     G     + ++   K+G   CYD+RFPEL   QA+ GAEI+ +PAA+
Sbjct: 123 ENGESWRESAAYHPGATA-RIADLPFGKLGFSICYDVRFPELFRQQAVAGAEIMSVPAAF 181

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAAS-E 227
            R    E HW  LL ARA++   ++VAA + G         G S IIDP+G  +A A   
Sbjct: 182 TRQT-GEAHWEILLRARAIENGLFVVAAAQGGTHEDGRETFGHSMIIDPWGRVLAQAGRT 240

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRR 255
              +I+AE+ P  V   RA++P L N R
Sbjct: 241 GEEIIIAEIDPLAVHTARAKIPNLKNAR 268


>UniRef50_C9D316 Hydrolase n=1 Tax=Silicibacter sp. TrichCH4B RepID=C9D316_9RHOB
          Length = 276

 Score =  254 bits (651), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 88/266 (33%), Positives = 122/266 (45%), Gaps = 13/266 (4%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
             AA Q   T+    N     +L+ +AA   A + +LPEA         +   +     E
Sbjct: 3   RFAAIQMCSTADVAANNAAIEALVREAAGQGARVISLPEAANILLRDQMEYPARCLPEAE 62

Query: 62  GEFLGRLRRESKRNMMTTILTIHVPSTPG--RAWNMLVALQA-GNIVARYAKLHLYD--- 115
              L   +  ++   +       +       R WN    +   G I ARY KLH +D   
Sbjct: 63  DSTLALCQALAQELGVWLHTGSLLLRAEEGSRIWNRGHMISPTGAITARYDKLHTFDVAL 122

Query: 116 --AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAW 173
             A    ESR V  G   A   E +G+K+GL  CYDLRF  L  A A  GA +L++PA++
Sbjct: 123 GGAGDFIESRAVAPGQRGAITCEADGLKLGLSICYDLRFSYLFRALASAGASVLMIPASF 182

Query: 174 VRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMP 229
                   HW  LL ARA++T  Y+VAA + G     +  GQSRII P G  +AAA + P
Sbjct: 183 -SPITGPLHWEPLLKARAIETGSYVVAAAQSGTRDGLRTHGQSRIISPMGEVLAAAGDEP 241

Query: 230 ALIMAEVTPERVRQVRAQLPVLNNRR 255
            +I AE+    V + R +LPVL   R
Sbjct: 242 GVICAEIDLAEVTETRRRLPVLAQTR 267


>UniRef50_C1B562 Putative hydrolase n=2 Tax=Actinomycetales RepID=C1B562_RHOOB
          Length = 278

 Score =  254 bits (651), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 83/252 (32%), Positives = 111/252 (44%), Gaps = 19/252 (7%)

Query: 18  AEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMM 77
                 L+  AA   A L  LPE        D D     A+ L+G FL  + R +KRN +
Sbjct: 32  IRRVDDLIDDAA--GADLVVLPELWAHGG-FDYDTWTDRAEPLDGTFLETMSRAAKRNSI 88

Query: 78  TTILTIHVPSTPG----RAWNMLVALQA-GNIVARYAKLHLYDAFAIQESRRVDAGNEIA 132
                  +         R WN  V     G I A Y K+H +  F+  E R + AG E  
Sbjct: 89  WLHAGSIIERENDTASARLWNTSVVFDPDGEIRATYRKIHRF-GFSDGEPRLLTAGTEPV 147

Query: 133 PL-LEVEGMK---VGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLA 188
              L         VGL TCYDLRFPEL       G E+LV+PAAW     +  HW+ L  
Sbjct: 148 STGLATAAGAETVVGLSTCYDLRFPELYRELVGAGTEVLVIPAAWP--RARVEHWTALGR 205

Query: 189 ARALDTTCYMVAAGECGNKNI----GQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQV 244
           ARA++   Y+V     G        G S+I+ P G  +AAA +   +I A +    +R++
Sbjct: 206 ARAIENQTYVVQCNVAGVDGDVALGGHSQIVAPDGTVVAAAGDSADMISATLELGSLREL 265

Query: 245 RAQLPVLNNRRF 256
           R   PVL +RR 
Sbjct: 266 RRTFPVLADRRL 277


>UniRef50_A5GU42 Nitrilase-related protein n=1 Tax=Synechococcus sp. RCC307
           RepID=A5GU42_SYNR3
          Length = 305

 Score =  254 bits (650), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 71/299 (23%), Positives = 122/299 (40%), Gaps = 44/299 (14%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAEN-----DASLFALPEALLARDDHDADLSVKSA 57
           VA  QF V+   + N +     + QA           L  LPE   +     A+   + A
Sbjct: 7   VALVQFQVSPEPQVNRQQVCHWLEQAMTQAGTSSSPKLLMLPEVWNSPY--QAERFAEFA 64

Query: 58  QLL--------EGEF--LGRLRRESKRNMMTTILTIHVP-STPGRAWNMLVALQA-GNIV 105
           + +        +G    L  +   +  + ++ I       S+ GR +N    +   G ++
Sbjct: 65  EPIPELGADLRDGPSDSLKVVADFAVSHRVSVIAGSIPECSSDGRIFNTATVISPAGCLL 124

Query: 106 ARYAKLHLYD-----AFAIQESRRVDAGNEIAPL----------LEVEGMKVGLMTCYDL 150
           A++ K+HL+D          ES  + AG++I  L                 +GL  CYD+
Sbjct: 125 AKHRKMHLFDVDIPGGIHFHESDSLTAGDQITVLSGVGDPLASGAATPP-NLGLQICYDI 183

Query: 151 RFPELALAQALQ-GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN--- 206
           RFPELAL    Q   +++  PA +        HW  ++ ARA+DT  +++A         
Sbjct: 184 RFPELALLMQQQLSCDVIACPAGF-STTTGPLHWHLVMRARAVDTQSFVLACCSARPPQD 242

Query: 207 --KN--IGQSRIIDPFGVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQL 261
                  G S ++DP+G  +A A     ++ AE+  +++   RA +P    RR    +L
Sbjct: 243 SGDYPSYGHSLVVDPWGHIVAEAGIGEEVVHAELDLDQIAAARAAIPTSRQRRGDVYRL 301


>UniRef50_Q47VH0 Hydrolase, carbon-nitrogen family n=1 Tax=Colwellia psychrerythraea
           34H RepID=Q47VH0_COLP3
          Length = 273

 Score =  254 bits (650), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 72/268 (26%), Positives = 124/268 (46%), Gaps = 20/268 (7%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQ--AAENDAS-LFALPEALLARDDHDADLSVKSA 57
           + ++A Q +  +  E N    A L+++  A++ D   L  LPE  L     D++    + 
Sbjct: 2   VKLSAIQLSSAANVETNLAKIAELLSKITASQEDVQHLVVLPECCLYFGSKDSEQLDLAI 61

Query: 58  QLLEGEFL-GRLRRESKRNMMTTILTIHV--PSTPGRAWNMLVALQA-GNIVARYAKLHL 113
               G  L   L   +K+  +  +        ++  +  N        G ++ +Y K+HL
Sbjct: 62  ASATGNDLCLALGELAKKFKVYLVAGTIPILSTSSTKFTNSSCVFNPEGELIGQYDKIHL 121

Query: 114 YDAF------AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEIL 167
           +D        +  ESR   AG EI+ +   E   +GL  C+DLRFP L    ++ GA+I+
Sbjct: 122 FDVNVSDSTKSYCESRYTQAGKEISMV-NTEFANIGLSVCFDLRFPNLFQQLSIAGADII 180

Query: 168 VLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGE-----CGNKNIGQSRIIDPFGVTI 222
            +P+A+ R    + HW TLL ARA++   Y+VAAG+      G +  G S II+P+G   
Sbjct: 181 TVPSAFTR-VTGKAHWQTLLQARAIENQVYIVAAGQEGVHENGRETWGHSMIINPWGEIE 239

Query: 223 AAASEMPALIMAEVTPERVRQVRAQLPV 250
            +       I  +   E + ++R  +P+
Sbjct: 240 QSIETGEGYISIDYHSEELTRIRQSMPL 267


>UniRef50_A6DN63 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Lentisphaera araneosa HTCC2155
           RepID=A6DN63_9BACT
          Length = 292

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 63/263 (23%), Positives = 117/263 (44%), Gaps = 18/263 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + V   Q + +  +E+N     S++ QA++N   L   PE  L       D++ ++A+  
Sbjct: 26  LRVCLVQMSSSPDFEENLAHAKSIIEQASQNRDELIIFPECALL--WAKTDITHQNAKTR 83

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA- 118
           E ++   L   SK   +  +          + +N        G+++  Y K HL+  F  
Sbjct: 84  E-QWTDLLSPLSKTYKIAIVWGGLAERQENKVFNSSFIFDADGHLLDVYRKTHLFQIFTP 142

Query: 119 ----IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               I E+   + G+    ++++    +G+  CYDLRFPE     A  G ++++  AA+ 
Sbjct: 143 GKKAIDETETYEHGDTGPCVVKINDWSIGISICYDLRFPEFLRNYA--GCDLMINSAAFT 200

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK------NIGQSRIIDPFGVTIAAASEM 228
           +   K  HW  L+ ARA++   Y++ + +CG          G S +IDP+G  +    E 
Sbjct: 201 KATGK-AHWEVLMRARAVENQSYVIGSAQCGRNELSGISAYGHSIVIDPWGEVLGDLGES 259

Query: 229 PALIMAEVTPERVRQVRAQLPVL 251
            A     +  + ++Q R  +P L
Sbjct: 260 IASQSFVLNKQIIQQTRETVPAL 282


>UniRef50_C6HVQ6 Putative carbon-nitrogen hydrolase n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HVQ6_9BACT
          Length = 279

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 64/274 (23%), Positives = 107/274 (39%), Gaps = 24/274 (8%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDH-DADLSVKSAQ 58
           + V   Q +      EKN +    L+    +  A L  LPE           D  V  A+
Sbjct: 6   IRVTVIQNSPQFGAPEKNRKEVEDLIFSQEDPSAGLIVLPELFATGYQFVSKDEVVSLAE 65

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFA 118
             +G     L   S++     +  + +    G   N  + +    ++A Y K+HL+D   
Sbjct: 66  PEDGPTFEFLSSLSRKTGAVVVGGLPIRRADG-ISNGALVVWGERLLASYDKVHLFD--- 121

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +E      G    P++      +G+M C+D  FPE   + AL GA ++  PA WV    
Sbjct: 122 -RERDFFVEGKSPLPVVTTPFGPMGVMICFDWLFPEALRSLALSGATVVAHPANWVLPFG 180

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGNK---------NIGQSRIIDPFGVTIAAAS-EM 228
            +     L   R+++   + V A   G +          IG+S+I+ P G  +A A  + 
Sbjct: 181 PQGM--IL---RSVENRLFTVTANRVGTEERGGLSPLRYIGESQIVSPKGEILARAGSDR 235

Query: 229 PALIMAEVTPERV--RQVRAQLPVLNNRRFAPPQ 260
           P +I A + PE    ++V  +      RR     
Sbjct: 236 PEIITATIRPEEALSKKVAEKSDFFEQRRPELYH 269


>UniRef50_Q1MYM0 Predicted amidohydrolase n=1 Tax=Bermanella marisrubri
           RepID=Q1MYM0_9GAMM
          Length = 274

 Score =  253 bits (648), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 65/271 (23%), Positives = 113/271 (41%), Gaps = 17/271 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
           + V   Q       + N     + + +  E  A+   LPE  +     +     ++    
Sbjct: 6   ITVGLVQMTSGKAVQPNLRAAEAAIKRCVEQGATTVLLPEMFVCLGVKNQVEIAQTQCQK 65

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP---STPGRAWNMLVALQAGNIVARYAKLHLYDA- 116
            G    +L   +K   +  I                  LV    G+ V +Y K+HL+D  
Sbjct: 66  GGPVRSQLSALAKDFKVNIIAGSMPLMSSVEDKVLAACLVFAADGSEVCQYDKVHLFDVD 125

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                   +ES    AG +   +  ++G   GL  CYDLRFPEL      Q  +++ +P+
Sbjct: 126 VSDNKGRYRESDTFIAGTQSKTV-SLDGTLYGLSVCYDLRFPELYQQYQKQSCQVVTVPS 184

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAAS 226
           A+      + HW TLL ARA++T  +++AA + G         GQS +I+P G  +    
Sbjct: 185 AFTY-TTGQKHWLTLLKARAIETQSFVMAANQVGTHEDGRITWGQSIVINPDGEIVGELD 243

Query: 227 -EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
            E    ++ E+  E  +++R  +P+L ++R 
Sbjct: 244 SEKAGELVVELDLELCQKIRQSMPLLKHKRL 274


>UniRef50_A9UWV2 Predicted protein (Fragment) n=1 Tax=Monosiga brevicollis
           RepID=A9UWV2_MONBE
          Length = 270

 Score =  253 bits (648), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 66/251 (26%), Positives = 113/251 (45%), Gaps = 17/251 (6%)

Query: 19  EICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMT 78
              A L AQAA+    +  LPEA         + +   A       L R     K++ + 
Sbjct: 4   RRIADLFAQAAKAQCRMLFLPEAFDWIG-LPVEETKSRAVPTTHAALTRYWDLCKQHSIW 62

Query: 79  TILTIHVPSTPG---RAWNMLVALQA-GNIVARYAKLHLYDA----FAIQESRRVDAGNE 130
                    T     R  N  V +   G + + Y K+HL+D        +ES     G  
Sbjct: 63  ASFGGAHVQTDDPQKRIANRHVIVDPLGQVRSTYDKIHLFDVDTADGVFKESDFTQPGRT 122

Query: 131 IAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHHWSTLLAAR 190
           +  + +     +GL  CYD+RFPE+      +GA++L++P+A++     + HW  LL AR
Sbjct: 123 LVTVPDTPLGTLGLSICYDVRFPEVYTELRARGADVLLVPSAFM-PSTGKAHWEALLRAR 181

Query: 191 ALDTTCYMVAAGECGNK------NIGQSRIIDPFGVTIAAASEM-PALIMAEVTPERVRQ 243
           A++T C+++AA + G        + G S ++DP+G  +         L+   +  ER+ +
Sbjct: 182 AIETQCFVIAAAQAGTHAPSTRRSYGHSLVVDPWGDVLVDGDAENEGLLAVTIDLERITE 241

Query: 244 VRAQLPVLNNR 254
           VR ++P+ N+R
Sbjct: 242 VRTKMPLANHR 252


>UniRef50_B7G2G6 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7G2G6_PHATR
          Length = 308

 Score =  253 bits (648), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 71/293 (24%), Positives = 126/293 (43%), Gaps = 41/293 (13%)

Query: 2   LVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLE 61
            +A  Q   TS    N    A     A  + A++  LPE      +  +    ++   ++
Sbjct: 14  RIAVAQLRSTSDKFSNLLDVARCAGWAKRDGAAMLFLPECCCFLGESASQTLEEADPPIQ 73

Query: 62  GE---FLGRLRRESKRNMMTTILTIHVPS----------TPGRAWNMLVALQA-GNIVAR 107
                 L  LR  ++ + +         S             R +N  + +   G +   
Sbjct: 74  DADILILDGLRNIARESGLWISAGGIHVSGAPPHDTADPDHSRVYNTHLIIDCVGTVKCL 133

Query: 108 YAKLHLYDAF-----AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQ 162
           Y K+HL+D       +++ES     G +   + +     +G+  CYDLRFPE+ +    Q
Sbjct: 134 YRKIHLFDVEIPGQVSLRESATTAPG-KAVKVCDSPIGCLGVTICYDLRFPEMYVKLTTQ 192

Query: 163 GAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKN-----IGQSRIIDP 217
           GA+IL++P+A+   P    HW TLL ARA++  C+++AA + G  N      G + I+DP
Sbjct: 193 GAQILLVPSAFTI-PTGTAHWHTLLRARAIENQCFVIAAAQFGEHNHKRESYGHALIVDP 251

Query: 218 FGVTIAAASEM---------------PALIMAEVTPERVRQVRAQLPVLNNRR 255
           +G  +A A                  P++++ E+  + V   R ++P+ N+RR
Sbjct: 252 WGEVLADAGGADGGGTVSIDASNLVTPSIMVQEIDLDLVTSARQRIPIQNHRR 304


>UniRef50_A8MC40 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Caldivirga maquilingensis IC-167
           RepID=A8MC40_CALMQ
          Length = 279

 Score =  253 bits (647), Expect = 5e-66,   Method: Composition-based stats.
 Identities = 67/261 (25%), Positives = 111/261 (42%), Gaps = 11/261 (4%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQ-AAENDASLFALPEALLARDDHDADLSVKSAQ 58
           + V   Q+A      E N +   +        +   +   PE  +       DL ++ A+
Sbjct: 2   LRVHLIQYASRLGDPEYNIDRLRNYAKANCRGDGNDVLITPELYIPGY-MSRDLLLQIAE 60

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTP-GRAWNMLVALQAGNIVARYAKLHLYDAF 117
            L+G+ +G L   ++    T I  I       G  +N  VA+    ++A Y K HL    
Sbjct: 61  PLDGKSIGELTEIAREGKCTIITGIAERDKDTGVVYNSAVAIGENGLMALYRKRHLPSYG 120

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              ESR    G   AP+  + G K GL  CYD  +PE++ +  L+GA + V  +A     
Sbjct: 121 VFDESRYFGVGRGDAPVFSMNGTKAGLAICYDAFYPEVSRSLMLKGARVQVYISA--APD 178

Query: 178 LKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAAS-EMPALI 232
           +   H+ T + ARA++   +++     G        G S I+DP G  +A A       +
Sbjct: 179 MSRPHFETFIRARAMENVSFVIYVNTIGQYDGLGFFGGSFIVDPLGEVVAKAKYYEEDTV 238

Query: 233 MAEVTPERVRQVRAQLPVLNN 253
           +AE+ P  V   R+  P+L +
Sbjct: 239 VAEIDPGLVDNYRSIRPILKD 259


>UniRef50_D0XIR2 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Alphaproteobacteria RepID=D0XIR2_9CAUL
          Length = 282

 Score =  252 bits (646), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 115/269 (42%), Gaps = 18/269 (6%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEG 62
           +A  Q    +  +        L+ QAA+  A L   PE     +       +      + 
Sbjct: 7   IALIQTRTPATAQAALAHVEPLIRQAADGGAKLILTPEGTNLLEQRRDRRGLAVTDEDQD 66

Query: 63  EFLGRLRRESKRNMMTTILTIHVP----STPGRAWNMLVALQ-AGNIVARYAKLHLYD-- 115
             +  LR  +    +  ++   +     +   RA N  + +   G IVARY KLH++D  
Sbjct: 67  AAVIGLRHLAAELGVWLLIGSAIVKSGHAGDDRAANRSLLIDANGTIVARYDKLHVFDVD 126

Query: 116 ---AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
                  +ES  +  G+  A +      ++GL  CYD+RFP L    A  GA ++ +PAA
Sbjct: 127 LANGETYRESSTIRPGD-GACVAGTPWGRMGLTICYDVRFPHLFRQLARAGACMIAVPAA 185

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAAS- 226
           +   P  E HW TLL ARA++T  +++A  + G         G S ++ P+G  IA    
Sbjct: 186 FTV-PTGEAHWETLLRARAIETGAFVLAPAQGGTHEDGRRTWGHSIVVGPWGEVIAKLDH 244

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRR 255
           + P ++ A +    V   R  +P L + R
Sbjct: 245 DEPGVLHATLDLAAVEAARTSVPQLRHDR 273


>UniRef50_Q46E33 Carbon-nitrogen hydrolase n=3 Tax=Methanosarcina RepID=Q46E33_METBF
          Length = 266

 Score =  252 bits (646), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 64/274 (23%), Positives = 120/274 (43%), Gaps = 23/274 (8%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M  A  Q  ++    ++N E   SL  +A   +A + A PE       +  D  V+ A+ 
Sbjct: 1   MKAACIQMNISLCSKKENLERALSLAEEAVSKEAEVLAFPEVFSTGFCY--DHIVELAET 58

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRA---------WNMLVALQAGNIVARYAK 110
             G  +G L   SK N      ++                  +N+   +++G +V  + K
Sbjct: 59  ASGPTIGALCDFSKENECILAGSMIEHREGSEFSSEMNIPPQFNLGFCIESGKLVGIHRK 118

Query: 111 LHLYDAFAIQESRRVDAGNEIAPL-LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVL 169
             LY      E      G +I P+ L+   + +GLM C ++R+PE++   AL+GA++LV 
Sbjct: 119 TQLYGL----EKEYFALGEDIHPIRLKKYDLSMGLMVCNEIRYPEVSRKLALEGADLLV- 173

Query: 170 PAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAA 225
            +A        + W  +  +RA++     +A    GN       G+S I D +G  +A A
Sbjct: 174 -SASDMPDFYIYPWRIMSLSRAIENQLPHIACNRAGNDRFSTYPGRSFIADGWGRILAEA 232

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
            +   +++ E+  E+++++R    ++ +RR    
Sbjct: 233 GKEECVLIGEIDLEKIKEIRKTGSIIEDRRPEIY 266


>UniRef50_A4BGL8 Predicted amidohydrolase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BGL8_9GAMM
          Length = 271

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 73/270 (27%), Positives = 108/270 (40%), Gaps = 17/270 (6%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLL 60
             V A Q   T     N       +A A   D  +  LPE        D        +  
Sbjct: 5   FTVCAVQMTSTDSLNDNLNWIDQQLANADLQDVQMLVLPETFALFGVKDQSALADQERAF 64

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVP--STPGRAWNML-VALQAGNIVARYAKLHLYDA- 116
           +G     +R+ +K   +  +                   V    G +V  Y K+HL+DA 
Sbjct: 65  DGSVGQAVRQWAKGYQVWIVAGTVPVMTDEDRLPRARCHVVDADGELVGFYDKIHLFDAE 124

Query: 117 -----FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPA 171
                 A +ES     G+++  LL     ++GL  CYDLRFPEL  A   QGA+ + LP+
Sbjct: 125 VGDRQGAYRESDSYSGGDKVVTLL-TPWGRLGLSVCYDLRFPELFRALNDQGADFVTLPS 183

Query: 172 AWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAAS 226
           A+      E HW  L  ARA++    ++A  +CG+        G S I+D +G    +  
Sbjct: 184 AFTA-KTGEAHWEPLCRARAIENGYSLIAVNQCGDHDAKRSTWGHSMIVDAWGRV-ESIG 241

Query: 227 EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
             P L   ++ P   + +R  LPV  NRR 
Sbjct: 242 LDPGLAFFKLDPAADQVIRNTLPVNANRRL 271


>UniRef50_A5TTZ3 Possible amidohydrolase n=4 Tax=Fusobacterium RepID=A5TTZ3_FUSNP
          Length = 274

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 60/263 (22%), Positives = 121/263 (46%), Gaps = 13/263 (4%)

Query: 1   MLVAAGQFAV-TSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
             +A  Q  +     EKN +     + +AA+ +  +   PE          D      + 
Sbjct: 9   FKIALAQIKIEQKNIEKNCKKIFERIEEAAKENVDIICFPELATIGYTITTDELQNLPED 68

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGR---AWNMLVALQA-GNIVARYAKLHLYD 115
               F+ +L+ ++K   +  ++      T  +    +N  + +   G I+A   K++L+ 
Sbjct: 69  FNNTFIEKLQEKAKLFKIHILVGYLESKTTKKSKDFYNSCIFIDDEGKILANARKVYLWK 128

Query: 116 AFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
               +E  +  AG++   + + +  K+G++ CYDL F E A  + L+GAEI+ +P+ W  
Sbjct: 129 ----KEKTKFKAGDK-FIVKDTKFGKIGILICYDLEFFEPARIECLKGAEIIFVPSLWSL 183

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAA-SEMPALIMA 234
               E+ W   LAA +L    +MV     G+   G+S+I++P G T+  A      L++A
Sbjct: 184 NA--ENRWHIDLAANSLFNLLFMVGCNAVGDSCCGKSKIVEPNGSTLIEASGTKEELLLA 241

Query: 235 EVTPERVRQVRAQLPVLNNRRFA 257
            +   ++ ++R ++P L++ +  
Sbjct: 242 TIDLAKLDEIRNKIPYLSDFKSD 264


>UniRef50_B4D6H9 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D6H9_9BACT
          Length = 260

 Score =  251 bits (643), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 76/255 (29%), Positives = 113/255 (44%), Gaps = 14/255 (5%)

Query: 5   AGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQLLEGE 63
           A Q   V      N     +L+  AA    SL  LPE        +  ++ + A+  +  
Sbjct: 8   AVQLDIVWEDKAANFRKVEALVDAAAPAPGSLVVLPEMFSCGFSMNLAVTRQGAEREDEA 67

Query: 64  FLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDAFAIQES 122
           F+  L   ++++ +     +          N  V     G +VARY K+H +      ES
Sbjct: 68  FIAAL---ARKHGVFITGGVVSRGAGEMGRNDAVVFSPEGKLVARYTKIHPFSGGG--ES 122

Query: 123 RRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKEHH 182
           +  +AG+EI    E  G  V    CYDLRFPE+  A A +GA + V+ A W     ++ H
Sbjct: 123 QGHEAGSEIVT-FEWGGFVVAPFVCYDLRFPEIFRAAARKGANLFVVMALWPVK--RQQH 179

Query: 183 WSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPALIMAEVTP 238
           W TLL ARA++   Y V     G +      G+S ++DP GV IA A E   ++ A + P
Sbjct: 180 WLTLLQARAIENQAYAVGVNRVGREPELLYAGRSVVVDPHGVIIADAGEREHILPATLEP 239

Query: 239 ERVRQVRAQLPVLNN 253
           E V   R   P L +
Sbjct: 240 EVVHSWRRDFPALRD 254


>UniRef50_A1RVM3 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=5 Tax=Thermoproteaceae RepID=A1RVM3_PYRIL
          Length = 269

 Score =  251 bits (643), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 66/264 (25%), Positives = 113/264 (42%), Gaps = 15/264 (5%)

Query: 1   MLVAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALL---ARDDHDADLSVKSA 57
             +   Q +       N +   SL+ +   ++  L  LPE  +        +   +   A
Sbjct: 2   FRLGIAQISPG-----NLDKLRSLVGR---SEPDLLLLPEYSMFDPTGLPPEEIWNKAVA 53

Query: 58  QLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGN-IVARYAKLHLYDA 116
                 F   + R ++      +          + +N  V +  G  +V  Y K HL+DA
Sbjct: 54  IED---FTSLIGRLARELGAYVVGGFLERGPRPKVYNTTVLVDPGGRVVGLYRKTHLFDA 110

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
           +  +ES  V+ G E++ +  V G +V    C++LRFPE+    AL GA+++ +PAAW  G
Sbjct: 111 YGYKESEFVEPGAELSQVYTVRGARVAFAVCFELRFPEVFRELALAGADLVAVPAAWYAG 170

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEV 236
           PLKE     L  ARA++   Y+  +   G +  G+S +++PFGV  A            +
Sbjct: 171 PLKEEILHILARARAIENGMYIAVSALWGPRFTGRSVVVNPFGVVEAELGAGERYREVLI 230

Query: 237 TPERVRQVRAQLPVLNNRRFAPPQ 260
               V + R  +P +  RR    +
Sbjct: 231 DLRLVEEARKTVPTIYLRRPHLYR 254


>UniRef50_C2D0V8 Possible N-carbamoylputrescine amidase n=1 Tax=Lactobacillus brevis
           subsp. gravesensis ATCC 27305 RepID=C2D0V8_LACBR
          Length = 291

 Score =  251 bits (643), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 65/273 (23%), Positives = 107/273 (39%), Gaps = 22/273 (8%)

Query: 1   MLV--AAGQFAVTSV-WEKNAEICASLMAQAAENDAS--LFALPEALLARDDHDADLSVK 55
           M +  A+ QF         N    A  + +         L   PE      +       +
Sbjct: 1   MKIQVASVQFQPQLNRVAFNLRAMAKWVNRIKSEQIDIKLIVFPELSTTGYECGTG-FYQ 59

Query: 56  SAQLLEGEFLGRLRRESKRNMMTTILTIHVPS--TPGRAWNMLVALQA-GNIVARYAKLH 112
            A+ + G+ +  ++  +KR  +  I           G  +N  + +   G IV  Y K+H
Sbjct: 60  LAETVTGQSVQYMQNVAKRYHVYLIFGFAQRDQTNAGTIYNSTMLINDQGQIVGTYQKVH 119

Query: 113 LYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
           L+D     E R    G    P+ + +   +G+M CYD  FPE+A   AL+ A++L +   
Sbjct: 120 LFDT----EQRYFTPGKT-YPVFKTKIGTIGMMICYDTFFPEVARILALEHADLLTISTN 174

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAAS-E 227
           W     +   W   + ARALD    +VAA   G        G S+IIDP G  +++   E
Sbjct: 175 W--ERPRIQDWELCVRARALDNIIPIVAANRIGFDKELDFFGHSKIIDPLGTVMSSLDSE 232

Query: 228 MPALIMAEVTPERVRQVRA-QLPVLNNRRFAPP 259
            P  + A +  E+ R +R     +  +      
Sbjct: 233 RPGYLQATIDYEQTRGLRHGYYSIYQDAHPETY 265


>UniRef50_A7H2U5 Carbon-nitrogen hydrolase n=5 Tax=Campylobacterales
           RepID=A7H2U5_CAMJD
          Length = 279

 Score =  251 bits (642), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 70/275 (25%), Positives = 116/275 (42%), Gaps = 24/275 (8%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           +  A  QFA  S   E+N          A E  A L  LPE   +    +       A  
Sbjct: 5   LKAALIQFAPLSYEREQNLNKSLIFTQTALEQGAKLVVLPELFDSGYCVEDKDFS-YALS 63

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           LE E    L+  +K+     I            ++    +    +V +Y K++L+     
Sbjct: 64  LEKELPSSLKELAKKYEAYIIACSIEKEDD-TLYDTAFIVGKEGLVGKYRKIYLFR---- 118

Query: 120 QESRRVDAGNEIAPLLEVEG----MKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVR 175
            E +R   G +  P+ E+      +K+GL  CY++ F E A   ALQGAE++  P+A+  
Sbjct: 119 DEKKRFARGQD-YPVFELVFKDFSLKLGLQICYEIGFGEGARFLALQGAELICYPSAF-- 175

Query: 176 GPLKEHHWSTLLAARALDTTCYMVAAGECGN----------KNIGQSRIIDPFGVTIAAA 225
           G  + + W     ARAL++  +++AA  CG+          +  G+S+II+P G  ++  
Sbjct: 176 GKARAYVWDLASRARALESGAFVLAANRCGSEISKLSGENLEFAGRSKIINPKGEILSEL 235

Query: 226 SEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           SE   +  A +   +V+  R  L  L +      Q
Sbjct: 236 SEKEGISYAVLDITQVKAQREYLTYLKDLDLDLSQ 270


>UniRef50_Q6AMZ4 Putative uncharacterized protein n=1 Tax=Desulfotalea psychrophila
           RepID=Q6AMZ4_DESPS
          Length = 258

 Score =  250 bits (640), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 67/264 (25%), Positives = 114/264 (43%), Gaps = 13/264 (4%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M ++A Q AV       +     + +    E+   L  LPE        +       A+ 
Sbjct: 1   MKISAIQLAVVEDDKAASIARARTEIELCRES--DLIILPEIWNTGF-MNFAAYRSLAEE 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVAL-QAGNIVARYAKLHLYDAFA 118
            +G  L  +R  + +          V     + +N    +   G+I+  Y K+HL+   +
Sbjct: 58  RKGPTLSMVREMAVKTSSFIHSGSFVEKIEDKYYNSSYLISPDGDILGNYRKIHLFGFAS 117

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
           + E+  + AG EI  ++  +   +G+ TC+DLRFPEL      QG EI ++ AAW     
Sbjct: 118 L-ETEILSAGQEI-SVINTKLGIIGMATCFDLRFPELFRKMVDQGTEIFLICAAWPLA-- 173

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMA 234
           +   W+ L   RAL+    +++A   G     +  G S I+ P G  +A A +M   I A
Sbjct: 174 RLADWALLNRVRALENQALLISANARGMSKGVQLAGNSMIVGPNGQILAQADDMDNSISA 233

Query: 235 EVTPERVRQVRAQLPVLNNRRFAP 258
           E+    V++ R   P L++R+   
Sbjct: 234 EINLNAVKEARCSFPALSSRKTFL 257


>UniRef50_A5C5V4 Putative uncharacterized protein n=1 Tax=Vitis vinifera
           RepID=A5C5V4_VITVI
          Length = 317

 Score =  250 bits (640), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 56/303 (18%), Positives = 108/303 (35%), Gaps = 45/303 (14%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDASLFALPEALLARDD--HDADLSVKSAQLL 60
           V+A QFA T     N      L+  A    A++  + E            +   + A+  
Sbjct: 9   VSALQFACTDDVPTNLNTAERLVRDAHRKGANIILIQELFEGYYFCQAQREDFFQRAKPY 68

Query: 61  EG-EFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           +G   + R+++ +K   +   ++    +      ++ +    G  +  Y K H+ D    
Sbjct: 69  KGHPTILRMQKLAKELGVVIPVSFFEEANNAHYNSIAIVDADGTDLGIYRKSHIPDGPGY 128

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGL-MTCYDLRFPELALAQAL----------------- 161
           QE    + G+    + E +  K+G+ +    + F +                        
Sbjct: 129 QEKFYFNPGDTGFKVFETKFAKIGVGLI--VILFRQTNRLMGCIQRVQYAGISGFQRQLE 186

Query: 162 ----QGAEILVLPAAWVRGPLKE-----HHWSTLLAARALDTTCYMVAAGECGNK----- 207
               QGAEIL+ P A    P         HW  ++   A      +VA+   G +     
Sbjct: 187 LWFFQGAEILLYPTAIGSEPQDTGLDSCDHWKRVMQGHAGANLVPLVASNRIGKEIIQTE 246

Query: 208 -------NIGQSRIIDPFGVTIAAASE-MPALIMAEVTPERVRQVRAQLPVLNNRRFAPP 259
                    G S I  P G  +AAA +   A+++A+   ++++  R    +  +RR    
Sbjct: 247 HGNTEITFYGNSFIAGPTGEIVAAADDKEEAVVVAQFDLDKIKSKRYSWGIFRDRRPDLY 306

Query: 260 QLL 262
           ++L
Sbjct: 307 KVL 309


>UniRef50_A7I641 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Candidatus Methanoregula boonei 6A8
           RepID=A7I641_METB6
          Length = 265

 Score =  250 bits (639), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 71/266 (26%), Positives = 116/266 (43%), Gaps = 15/266 (5%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M   + Q + V    ++  E   +   +AA   A+L + PE      D  +  +      
Sbjct: 1   MRCCSAQISGVWEAPDETLEQVETCFFRAAREGAALISFPEQFATGWDPCSTKNTGG--- 57

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQ-AGNIVARYAKLHLYDAFA 118
           + G  +  LR  +K++ +  I +      P +  N  +A+   G I+  YAK+HL+    
Sbjct: 58  ISGTVVNGLRELAKKHKIAVIGSFRETCLP-KPRNTAIAIDRNGTILTTYAKIHLFTPG- 115

Query: 119 IQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
            +E +    G        +EG+++GL  CYDLRFPE+      +G   +++PAAW +  L
Sbjct: 116 -REDQAFSPG-TGLATFALEGVQIGLAICYDLRFPEIFRLYRQRGVHAVIVPAAWPKSRL 173

Query: 179 KEHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMA 234
           K  HW   + +RA +   Y+      G     +  G S   DP G  IA A     L+  
Sbjct: 174 K--HWELFIQSRAAENQMYIAGVNTSGTNPVDQYAGASMTADPHGTIIARAGTEQELLYY 231

Query: 235 EVTPERVRQVRAQLPVLNNRRFAPPQ 260
           E+ P  V Q R   PV N+R+    +
Sbjct: 232 EIDPLIVEQARRDFPVENDRKDELYR 257


>UniRef50_Q6MPB5 Putative amidohydrolase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MPB5_BDEBA
          Length = 276

 Score =  250 bits (639), Expect = 5e-65,   Method: Composition-based stats.
 Identities = 73/272 (26%), Positives = 112/272 (41%), Gaps = 23/272 (8%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAENDAS--LFALPEALLARDDHDADLSVKSAQLL 60
           VAA Q         N      L+ +A  N A     + PE  L       +        L
Sbjct: 7   VAAVQMTSVDDVTTNLAQMEELLKEAF-NGAQPRFVSFPENCL--YLRLKEGEKIEGLTL 63

Query: 61  EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQA-GNIVARYAKLHLYDA--- 116
                 RL   +K       L        G  +N    +   G +   Y K+HL+D    
Sbjct: 64  SHPAFARLSELAKHYNTYLHLGSIPLYLEGHLYNSSALITPEGEVQPTYQKMHLFDIQLD 123

Query: 117 --FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWV 174
               ++ES     G     +++++G KVG   CYD+RF EL    A +  ++++LPAA+ 
Sbjct: 124 GQAPLRESDVFRHGQTP-NVIDIDGWKVGEAICYDVRFAELFSQYARREVDVILLPAAF- 181

Query: 175 RGPLKEHHWSTLLAARALDTTCYMVAAGECGNK---------NIGQSRIIDPFGVTIAAA 225
                E HW  LL ARA++   Y++AA + G             G S IIDP+G  +   
Sbjct: 182 LVKTGEAHWEILLRARAIENQSYVIAAAQGGTHTGLRGGTRETYGHSLIIDPWGAVVGQV 241

Query: 226 S-EMPALIMAEVTPERVRQVRAQLPVLNNRRF 256
               P + +++ T ER+  VR Q+P+  +RR 
Sbjct: 242 EKRQPGVTISKFTRERIDSVRRQIPMKFHRRL 273


>UniRef50_Q4K6V5 Carbon-nitrogen hydrolase family protein n=3 Tax=Pseudomonas
           RepID=Q4K6V5_PSEF5
          Length = 263

 Score =  249 bits (638), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 61/255 (23%), Positives = 101/255 (39%), Gaps = 18/255 (7%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + +A  Q        + N E    L+ QA    A L  LPE        ++      A+ 
Sbjct: 10  LNLALIQTTLAWHDRQANFEHFEQLLEQA--RGADLIILPEMFTTGFSMES---ATLAEA 64

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
             G     LR ++K+       ++ + +  G   N L+  +    V  Y K HL+     
Sbjct: 65  ENGPTSKWLRGQAKKLNAVITGSVIIQAADGSHRNRLLWARPDGEVWHYDKRHLFRMAG- 123

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E      G       E++G ++  + CYDLRFP  +     Q  ++L+  A W     +
Sbjct: 124 -EHNHYTPGERQVQ-FELKGWRIRPLICYDLRFPVWSRDA--QDTDLLLYTANWPGA--R 177

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPALIMA 234
             HW+ LL ARA++  CY+ A    G         G S+++D  G T+ +A E   +   
Sbjct: 178 RLHWNRLLPARAIENLCYVAAVNRVGTDGKGFAYTGDSQVLDYQGETLLSAGEADGVFQV 237

Query: 235 EVTPERVRQVRAQLP 249
            +    +   RA+ P
Sbjct: 238 CLNAGELAAYRARFP 252


>UniRef50_A0B689 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Methanosaeta thermophila PT RepID=A0B689_METTP
          Length = 245

 Score =  249 bits (637), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 69/260 (26%), Positives = 107/260 (41%), Gaps = 16/260 (6%)

Query: 1   MLVAAGQFAVTS-VWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           M  A  Q +V       N      L +  A+  A +  LPE  L    +D        + 
Sbjct: 1   MRAACVQLSVRECDVGDNKRRALQLSSDVADIGADIIVLPELFLTGFCYDLKP-----ES 55

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           +    L   R  S  +    + +I   S  G   NM   +  G     Y K H +     
Sbjct: 56  IPYPSLMSFRALSLDSGAILVGSIMASSDRGPI-NMGFCMA-GAETGFYCKTHPFG---- 109

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E +    G  IAP+ +V G+ +GL  CYD+RFPE+A      GA++LV  A +     +
Sbjct: 110 DEKKHFIPGEIIAPV-KVGGLSIGLEICYDIRFPEVARKLCASGADLLVTIAQFPAE--R 166

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPE 239
            HHW  L+ ARA++   + +A    G+   G S I+ P G  +A A     +I A++  +
Sbjct: 167 IHHWRALVTARAIENQIHHIACNASGSAG-GSSMIVGPAGEVLAEAGVEECVITADLDLD 225

Query: 240 RVRQVRAQLPVLNNRRFAPP 259
              +VR  +    +RR    
Sbjct: 226 ERDRVRRAITCWEDRRPELY 245


>UniRef50_A6TL48 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=3 Tax=Bacteria RepID=A6TL48_ALKMQ
          Length = 296

 Score =  249 bits (636), Expect = 9e-65,   Method: Composition-based stats.
 Identities = 64/274 (23%), Positives = 115/274 (41%), Gaps = 21/274 (7%)

Query: 3   VAAGQFAVTSV-WEKNAEICASLMAQAAEN-DASLFALPEALLARDDHDA--DLSVKSAQ 58
            A  Q A+     ++N E  A  + +AA+  +A L   PE++      +   D   +  +
Sbjct: 6   AACVQIAIKPNEIQRNIEKAAYWLERAAKEYEAELVVFPESITTGFSPNMTVDAFYEILE 65

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPSTPGR-AWNMLVALQA-GNIVARYAKLHLYDA 116
            + G     +++ +K      +  ++      R  +N  + +   G I+ +Y K H +  
Sbjct: 66  PIPGRHTRDIQKLAKELGTHVVFPLYERGKNKREVFNSSLMIDDRGEIIGKYRKTHPFPT 125

Query: 117 FAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRG 176
              +       GNE   +++ +  K+G++ CYD  FPEL+   AL+GAEI+  P+A +R 
Sbjct: 126 ERKEGGGWTTPGNE-TVVVDTKLGKIGMIICYDGDFPELSRVLALKGAEIITRPSALLRS 184

Query: 177 PLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASEMPAL 231
                 W     ARA D   Y++     G         G S I+ P   T+A A     +
Sbjct: 185 F---EIWEMTNKARAYDNHVYVLGVNAIGPDAAENYYFGHSMIVSPIAQTLAQARGTEEI 241

Query: 232 IMAEVTPERVRQV----RA--QLPVLNNRRFAPP 259
           I A++ P+ ++ V    R+      L +R     
Sbjct: 242 IAAKLDPDPIKYVSYGTRSPMIFDHLEDRNVKVY 275


>UniRef50_B0MXF9 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MXF9_9BACT
          Length = 253

 Score =  248 bits (635), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 19/258 (7%)

Query: 1   MLVAAGQFA-VTSVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVKSAQL 59
           + VA  QF  V      N      ++A+A   DA L  LPE        D     + AQ 
Sbjct: 3   LKVALCQFDMVWEDTAANLRTAGRMVAEA---DADLVILPEMFATGFVTDPG---RVAQP 56

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
           + GE +  + R  +      +    +    GR +N L+ ++      +  K HL+     
Sbjct: 57  MSGEIVQEMTRWVRTTGKA-VAGSLIVEEEGRYYNRLLFIKPSGERVQSDKRHLFSIGG- 114

Query: 120 QESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLK 179
            E      G E   ++E  G++  L  CYDLRFP  +        + ++  A+W  G  +
Sbjct: 115 -EGANFCPGRERG-VVEYGGIRFLLQVCYDLRFPVWSRC--RNDYDAIIYVASWPAG--R 168

Query: 180 EHHWSTLLAARALDTTCYMVAAGECGN----KNIGQSRIIDPFGVTIAAASEMPALIMAE 235
              W TLL ARA++   Y++     G+       G S +I   G T+A A E   L+ A 
Sbjct: 169 RDVWRTLLRARAIENQAYVLGVNRTGDDPRLHYSGDSAVIGCKGETLAEAGEGETLLTAR 228

Query: 236 VTPERVRQVRAQLPVLNN 253
           +  + +R+ R + P   +
Sbjct: 229 LDMDELRRFREKFPAWRD 246


>UniRef50_C8PKQ1 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PKQ1_9PROT
          Length = 268

 Score =  247 bits (633), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 63/273 (23%), Positives = 117/273 (42%), Gaps = 20/273 (7%)

Query: 1   MLVAAGQFAVT-----SVWEKNAEICASLMAQAAENDASLFALPEALLARDDHDADLSVK 55
           M +A  Q  V      +  E+N      L+ +A +  A +  LPEA       +     +
Sbjct: 1   MKIAILQMDVKVAQNFADCEQNFIRARELINRALKRGADVAVLPEAFNT--SFNTAKFKE 58

Query: 56  SAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYD 115
            A          L   S++N    I          + +N     Q G  + RY K+H + 
Sbjct: 59  LADTNAAHTKKFLSEISQKNGAVLIGGAINSRQD-KIYNSAFVYQNGAKILRYDKIHAFS 117

Query: 116 AFAIQESRRVDAGNEIAPL---LEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAA 172
               +E+  V  G+++       +   +K+G++ CYDLRF E+  A AL GA+I+ + A 
Sbjct: 118 LA--RENEIVSGGDKLGICEIKFQNRAVKIGVVICYDLRFCEIFRALALCGAQIVFVIAQ 175

Query: 173 WVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNK-----NIGQSRIIDPFGVTIAAASE 227
           + +   +  H+ TL  AR+++   ++ A   CG+        G S +I P G  +A   +
Sbjct: 176 FAQS--RIEHFITLAKARSIENQIFICAVNGCGDTGQGESFGGNSMLIGPGGEIVARLGK 233

Query: 228 MPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
             A+ +A    + + + RA++ +L + +    +
Sbjct: 234 KEAVKIARANLDEILKFRAKMDLLKDMKPEIYK 266


>UniRef50_C6QR30 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
           n=1 Tax=Geobacillus sp. Y4.1MC1 RepID=C6QR30_9BACI
          Length = 455

 Score =  247 bits (631), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 63/269 (23%), Positives = 101/269 (37%), Gaps = 21/269 (7%)

Query: 1   MLVAAGQFAVT-SVWEKNAEICASLMAQAAENDASLFALPEALLARD-DHDADLSVKSAQ 58
           + VAA QF       E N      L  +AAEN A L   PE   +     +        +
Sbjct: 7   VKVAAVQFESRLGDLEGNRHRMLELAEEAAENGAKLIVFPEMATSGYIFENRQEIAPYVE 66

Query: 59  LLEGEFLGRLRRESKRNMMTTILTIHVPST-PGRAWNMLVALQAGNIVARYAKLHLYDAF 117
            + G      +  +K+     ++ +    +     +N  V +    ++ RY K HL+ A 
Sbjct: 67  PIPGPTTELFQTVAKKYSCYLVIGLPEVDSFTEIFYNSAVLIGPEGVIGRYRKTHLFAA- 125

Query: 118 AIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGP 177
              + R    GNE  P+   +   + ++ C D  + E A   AL+GA+I+  P  WV   
Sbjct: 126 ---DPRWAREGNEGIPVFSTKIGNIAMLICMDAMYFEPARIAALKGADIIAFPTNWVGES 182

Query: 178 LKEH--HWSTLLAARALDTTCYMVAAGECGNK----NIGQSRIIDPFGVTIAAASEMPAL 231
                  WS     RA++   Y VAA   G +      G S +I P G           +
Sbjct: 183 NNPPSKTWSL----RAMENGLYWVAANRWGQERGAQFTGGSAVIGPTGEVQDWKLSGDGI 238

Query: 232 IMAEVTPERVRQVRAQLPVLNNRRFAPPQ 260
           +     P   R+ R    +L +R+    Q
Sbjct: 239 VYGVYQPHDDRKQR----ILESRQPKAYQ 263



 Score = 83.1 bits (205), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 29/185 (15%), Positives = 52/185 (28%), Gaps = 22/185 (11%)

Query: 3   VAAGQFAVTSVWEKNAEICASLMAQAAEN---DASLFALPEALLARDDHDADLSVKSAQL 59
           V   Q +     E+     +  +    +       L  LPE  +   +            
Sbjct: 288 VCVAQLSNHGTLEQWLSNVSEWLESRKDEINFKRRLVILPEMDITGTERAGTSLEFY--- 344

Query: 60  LEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLHLYDAFAI 119
                   L   + +  +  I          R  +    L     +  Y ++H       
Sbjct: 345 -----QHALHSIASKYGVYIIAAAPQHMDGHRV-STAFLLGPEGCIGAYQQVH------- 391

Query: 120 QESRRVDAGNEI-APLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPL 178
                +  G       L +   K+GL+T  D  FPE     A QGA+++ + A+      
Sbjct: 392 --RNALGRGEYGSFCTLALPFAKIGLLTGGDAEFPESYRILAKQGADLIAVSASGTETYH 449

Query: 179 KEHHW 183
              H 
Sbjct: 450 SWMHR 454


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.313    0.190    0.651 

Lambda     K      H
   0.267   0.0585    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,189,845,979
Number of Sequences: 3077464
Number of extensions: 125195472
Number of successful extensions: 323429
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 2205
Number of HSP's successfully gapped in prelim test: 1434
Number of HSP's that attempted gapping in prelim test: 308748
Number of HSP's gapped (non-prelim): 4145
length of query: 262
length of database: 1,040,396,356
effective HSP length: 126
effective length of query: 136
effective length of database: 652,635,892
effective search space: 88758481312
effective search space used: 88758481312
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (20.9 bits)
S2: 93 (39.9 bits)
