Phyre 2 Results for P0AER8

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | P0AER8
Date | Thu Jan 5 11:24:03 GMT 2012
Unique Job ID | f6f5bc7866ce496a

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d2nwwa1
Top template information
Fold:Proton glutamate symport protein Superfamily:Proton glutamate symport protein Family:Proton glutamate symport protein
Confidence and coverage
Confidence: | 93.7% | Coverage: | 64%
256 residues ( 64% of your sequence) have been modelled with 93.7% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | F | H | L | D | T | L | A | T | L | V | A | A | T | L | T | L | L | L | G | R | K | L | V | H | S | V | S | F | L | K | K | Y | T | I | P | E | P | V | A | G | G | L | L | V | A | L | A | L | L | V | L | K | K | S | M | G | W | E | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | N | F | D | M | S | L | R | D | P | L | M | L | A | F | F | A | T | I | G | L | N | A | N | I | A | S | L | R | A | G | G | R | V | V | G | I | F | L | I | V | V | V | G | L | L | V | M | Q | N | A | I | G | I | G | M | A | S | L | L | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | L | D | P | L | M | G | L | L | A | G | S | I | T | L | S | G | G | H | G | T | G | A | A | W | S | K | L | F | I | E | R | Y | G | F | T | N | A | T | E | V | A | M | A | C | A | T | F | G | L | V | L | G | G | L | I | G | G | P | V | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | R | Y | L | V | K | H | S | T | T | P | N | G | I | P | D | D | Q | E | V | P | T | A | F | E | K | P | D | V | G | R | M | I | T | S | L | V | L | I | E | T | I | A | L | I | A | I | C | L | T | V | G | K | I | V | A | Q | L | L | A | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | T | A | F | E | L | P | T | F | V | C | V | L | F | V | G | V | I | L | S | N | G | L | S | I | M | G | F | Y | R | V | F | E | R | A | V | S | V | L | G | N | V | S | L | S | L | F | L | A | M | A | L | M | G | L | K | L | W | E | L | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | S | L | A | L | P | M | L | A | I | L | V | V | Q | T | I | F | M | A | L | Y | A | I | F | V | T | W | R | M | M | G | K | N | Y | D | A | A | V | L | A | A | G | H | C | G | F | G | L | G | A | T | P | T | A | I | A | N | M | Q | A | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | .
Sequence |  | T | E | R | F | G | P | S | H | M | A | F | L | V | V | P | M | V | G | A | F | F | I | D | I | V | N | A | L | V | I | K | L | Y | L | M | L | P | I | F | A | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d2nwwa1 |

### PDB 2nww chain A domain 1

Region: 39 - 376
Aligned: 256
Modelled: 256
Confidence: 93.7%
Identity: 17%
Fold: Proton glutamate symport protein
Superfamily: Proton glutamate symport protein
Family: Proton glutamate symport protein

Phyre2
2 |
| c1zcdA_ |

### PDB 1zcd chain A

Region: 11 - 175
Aligned: 157
Modelled: 165
Confidence: 28.7%
Identity: 12%
PDB header:membrane protein
Chain: A: PDB Molecule:na(+)/h(+) antiporter 1;
PDBTitle: crystal structure of the na+/h+ antiporter nhaa

Phyre2
3 |
| d1e9yb2 |

### PDB 1e9y chain B domain 2

Region: 335 - 365
Aligned: 30
Modelled: 31
Confidence: 24.9%
Identity: 33%
Fold: TIM beta/alpha-barrel
Superfamily: Metallo-dependent hydrolases
Family: alpha-subunit of urease, catalytic domain

Phyre2
4 |
| d1ejxc2 |

### PDB 1ejx chain C domain 2

Region: 334 - 365
Aligned: 30
Modelled: 32
Confidence: 23.4%
Identity: 37%
Fold: TIM beta/alpha-barrel
Superfamily: Metallo-dependent hydrolases
Family: alpha-subunit of urease, catalytic domain

Phyre2
5 |
| c3b9yA_ |

### PDB 3b9y chain A

Region: 138 - 211
Aligned: 73
Modelled: 74
Confidence: 18.2%
Identity: 14%
PDB header:transport protein
Chain: A: PDB Molecule:ammonium transporter family rh-like protein;
PDBTitle: crystal structure of the nitrosomonas europaea rh protein

Phyre2
6 |
| c3chxF_ |

### PDB 3chx chain F

Region: 11 - 52
Aligned: 42
Modelled: 42
Confidence: 8.7%
Identity: 19%
PDB header:membrane protein
Chain: F: PDB Molecule:pmoa;
PDBTitle: crystal structure of methylosinus trichosporium ob3b2 particulate methane monooxygenase (pmmo)

Phyre2
7 |
| d3bl2a1 |

### PDB 3bl2 chain A domain 1

Region: 364 - 395
Aligned: 32
Modelled: 32
Confidence: 8.4%
Identity: 19%
Fold: Toxins' membrane translocation domains
Superfamily: Bcl-2 inhibitors of programmed cell death
Family: Bcl-2 inhibitors of programmed cell death

Phyre2
8 |
| c1yewF_ |

### PDB 1yew chain F

Region: 11 - 52
Aligned: 42
Modelled: 42
Confidence: 7.9%
Identity: 24%
PDB header:oxidoreductase, membrane protein
Chain: F: PDB Molecule:particulate methane monooxygenase, a subunit;
PDBTitle: crystal structure of particulate methane monooxygenase

Phyre2
9 |
| d2fnaa1 |

### PDB 2fna chain A domain 1

Region: 31 - 41
Aligned: 11
Modelled: 11
Confidence: 7.2%
Identity: 36%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Family: Helicase DNA-binding domain

Phyre2
10 |
| c3gd8A_ |

### PDB 3gd8 chain A

Region: 19 - 125
Aligned: 107
Modelled: 107
Confidence: 7.1%
Identity: 19%
PDB header:membrane protein
Chain: A: PDB Molecule:aquaporin-4;
PDBTitle: crystal structure of human aquaporin 4 at 1.8 and its mechanism of2 conductance

Phyre2
11 |
| d2pv7a2 |

### PDB 2pv7 chain A domain 2

Region: 166 - 209
Aligned: 44
Modelled: 44
Confidence: 6.9%
Identity: 20%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Phyre2
12 |
| c3cpiH_ |

### PDB 3cpi chain H

Region: 329 - 349
Aligned: 21
Modelled: 21
Confidence: 6.9%
Identity: 29%
PDB header:protein transport
Chain: H: PDB Molecule:rab gdp-dissociation inhibitor;
PDBTitle: crystal structure of yeast rab-gdi

Phyre2
13 |
| d1ivya_ |

### PDB 1ivy chain A

Region: 134 - 153
Aligned: 18
Modelled: 20
Confidence: 6.4%
Identity: 39%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Serine carboxypeptidase-like

Phyre2
14 |
| c3czcA_ |

### PDB 3czc chain A

Region: 343 - 365
Aligned: 23
Modelled: 23
Confidence: 6.1%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:rmpb;
PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans

Phyre2
15 |
| c2d57A_ |

### PDB 2d57 chain A

Region: 19 - 112
Aligned: 94
Modelled: 94
Confidence: 6.1%
Identity: 19%
PDB header:transport protein
Chain: A: PDB Molecule:aquaporin-4;
PDBTitle: double layered 2d crystal structure of aquaporin-4 (aqp4m23) at 3.2 a2 resolution by electron crystallography

Phyre2
16 |
| c3hd6A_ |

### PDB 3hd6 chain A

Region: 138 - 211
Aligned: 74
Modelled: 74
Confidence: 5.9%
Identity: 12%
PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:ammonium transporter rh type c;
PDBTitle: crystal structure of the human rhesus glycoprotein rhcg

Phyre2
17 |
| d1ohea2 |

### PDB 1ohe chain A domain 2

Region: 342 - 370
Aligned: 27
Modelled: 29
Confidence: 5.5%
Identity: 33%
Fold: (Phosphotyrosine protein) phosphatases II
Superfamily: (Phosphotyrosine protein) phosphatases II
Family: Dual specificity phosphatase-like

Phyre2
18 |
| c3pduF_ |

### PDB 3pdu chain F

Region: 166 - 220
Aligned: 55
Modelled: 55
Confidence: 5.3%
Identity: 16%
PDB header:oxidoreductase
Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+

Phyre2

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d2nwwa1 |
|  | 93.7 | 17 | Fold:Proton glutamate symport protein Superfamily:Proton glutamate symport protein Family:Proton glutamate symport protein
2 | c1zcdA_ |
|  | 28.7 | 12 | PDB header:membrane protein Chain: A: PDB Molecule:na(+)/h(+) antiporter 1; PDBTitle: crystal structure of the na+/h+ antiporter nhaa
3 | d1e9yb2 |
|  | 24.9 | 33 | Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain
4 | d1ejxc2 |
|  | 23.4 | 37 | Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain
5 | c3b9yA_ |
|  | 18.2 | 14 | PDB header:transport protein Chain: A: PDB Molecule:ammonium transporter family rh-like protein; PDBTitle: crystal structure of the nitrosomonas europaea rh protein
6 | c3chxF_ |
|  | 8.7 | 19 | PDB header:membrane protein Chain: F: PDB Molecule:pmoa; PDBTitle: crystal structure of methylosinus trichosporium ob3b2 particulate methane monooxygenase (pmmo)
7 | d3bl2a1 |
|  | 8.4 | 19 | Fold:Toxins' membrane translocation domains Superfamily:Bcl-2 inhibitors of programmed cell death Family:Bcl-2 inhibitors of programmed cell death
8 | c1yewF_ |
|  | 7.9 | 24 | PDB header:oxidoreductase, membrane protein Chain: F: PDB Molecule:particulate methane monooxygenase, a subunit; PDBTitle: crystal structure of particulate methane monooxygenase
9 | d2fnaa1 |
|  | 7.2 | 36 | Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Helicase DNA-binding domain
10 | c3gd8A_ |
|  | 7.1 | 19 | PDB header:membrane protein Chain: A: PDB Molecule:aquaporin-4; PDBTitle: crystal structure of human aquaporin 4 at 1.8 and its mechanism of2 conductance
11 | d2pv7a2 |
|  | 6.9 | 20 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
12 | c3cpiH_ |
|  | 6.9 | 29 | PDB header:protein transport Chain: H: PDB Molecule:rab gdp-dissociation inhibitor; PDBTitle: crystal structure of yeast rab-gdi
13 | d1ivya_ |
|  | 6.4 | 39 | Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Serine carboxypeptidase-like
14 | c3czcA_ |
|  | 6.1 | 22 | PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans
15 | c2d57A_ |
|  | 6.1 | 19 | PDB header:transport protein Chain: A: PDB Molecule:aquaporin-4; PDBTitle: double layered 2d crystal structure of aquaporin-4 (aqp4m23) at 3.2 a2 resolution by electron crystallography
16 | c3hd6A_ |
|  | 5.9 | 12 | PDB header:membrane protein, transport protein Chain: A: PDB Molecule:ammonium transporter rh type c; PDBTitle: crystal structure of the human rhesus glycoprotein rhcg
17 | d1ohea2 |
|  | 5.5 | 33 | Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like
18 | c3pduF_ |
|  | 5.3 | 16 | PDB header:oxidoreductase Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein; PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0