BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (292 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9KTE3 Magnesium and cobalt efflux protein corC n=42 Ta...   373   e-102
UniRef50_Q9CM13 Magnesium and cobalt efflux protein corC n=264 T...   358   1e-97
UniRef50_Q7VRA4 Haemolysin-related protein n=2 Tax=Candidatus Bl...   342   8e-93
UniRef50_Q48DN5 Metal ion transporter, putative n=16 Tax=Proteob...   280   3e-74
UniRef50_A4VQY6 Metal ion transporter, putative n=2 Tax=Gammapro...   273   6e-72
UniRef50_Q1YQV9 Magnesium and cobalt efflux protein CorC n=1 Tax...   260   3e-68
UniRef50_B5JWG7 CBS domain containing protein n=3 Tax=Gammaprote...   259   8e-68
UniRef50_B9ZL46 CBS domain containing protein n=2 Tax=Gammaprote...   256   5e-67
UniRef50_Q5ZVK1 Mg2+ and Co2+ transporter CorC n=6 Tax=Legionell...   254   3e-66
UniRef50_B8KMV1 Magnesium and cobalt efflux protein CorC n=3 Tax...   253   5e-66
UniRef50_D0KZZ4 CBS domain containing protein n=1 Tax=Halothioba...   248   2e-64
UniRef50_A8PND0 Magnesium and cobalt efflux protein CorC n=1 Tax...   247   4e-64
UniRef50_C7RRT5 CBS domain containing protein n=1 Tax=Candidatus...   247   4e-64
UniRef50_A5EY48 Transporter associated domain protein n=2 Tax=Ca...   244   2e-63
UniRef50_Q0VN63 Metal ion transporter n=15 Tax=Gammaproteobacter...   241   3e-62
UniRef50_A9M203 Magnesium and cobalt transporter n=27 Tax=Neisse...   238   2e-61
UniRef50_B2I8U5 CBS domain containing protein n=17 Tax=Xanthomon...   236   6e-61
UniRef50_A1WVF4 CBS domain containing protein n=2 Tax=Ectothiorh...   235   1e-60
UniRef50_B7J5B5 Magnesium and cobalt efflux protein, putative n=...   232   1e-59
UniRef50_C4GJN3 Putative uncharacterized protein n=1 Tax=Kingell...   230   4e-59
UniRef50_Q3JVV5 Magnesium and cobalt efflux protein CorC n=105 T...   228   2e-58
UniRef50_A4NW42 N-acetyl-anhydromuranmyl-L-alanine amidase n=1 T...   228   2e-58
UniRef50_B6BWN1 Putative uncharacterized protein n=1 Tax=beta pr...   226   7e-58
UniRef50_A6VZE4 CBS domain containing protein n=9 Tax=Gammaprote...   218   2e-55
UniRef50_A5CVQ3 Magnesium/cobalt efflux protein n=5 Tax=Bacteria...   218   3e-55
UniRef50_C3X3R1 Magnesium and cobalt efflux protein n=1 Tax=Oxal...   209   1e-52
UniRef50_Q1Q8E9 CBS domain n=21 Tax=Moraxellaceae RepID=Q1Q8E9_P...   201   2e-50
UniRef50_Q31IF1 Transporter associated domain/CBS domain protein...   199   1e-49
UniRef50_C6NUU3 Magnesium and cobalt efflux protein CorC n=1 Tax...   199   1e-49
UniRef50_A9BXY0 CBS domain containing protein n=17 Tax=cellular ...   194   3e-48
UniRef50_Q14IK8 Metal ion transporter protein n=17 Tax=Francisel...   188   1e-46
UniRef50_Q3A2F6 Uncharacterized CBS domain-containing protein n=...   188   2e-46
UniRef50_C1SMP1 CBS domain-containing protein n=1 Tax=Denitrovib...   185   1e-45
UniRef50_C8X404 CBS domain containing protein n=2 Tax=Desulfovib...   185   2e-45
UniRef50_A7NHB2 CBS domain containing protein n=1 Tax=Roseiflexu...   182   1e-44
UniRef50_D2DIN9 CBS domain-containing protein n=1 Tax=uncultured...   182   1e-44
UniRef50_A9I003 Magnesium and cobalt efflux protein n=5 Tax=Bord...   182   1e-44
UniRef50_D1CDD2 CBS domain containing protein n=1 Tax=Thermobacu...   180   5e-44
UniRef50_D0MD79 CBS domain containing protein n=1 Tax=Rhodotherm...   179   1e-43
UniRef50_D1Y8K6 CBS/transporter domain protein n=1 Tax=Pyramidob...   177   3e-43
UniRef50_Q310P2 CBS n=6 Tax=Desulfovibrionaceae RepID=Q310P2_DESDG    175   1e-42
UniRef50_D0RQJ3 CBS domain containing protein n=1 Tax=alpha prot...   175   2e-42
UniRef50_C7LZP2 CBS domain containing protein n=1 Tax=Acidimicro...   175   2e-42
UniRef50_D1C1Y5 CBS domain containing protein n=1 Tax=Sphaerobac...   174   3e-42
UniRef50_B7IDY0 Integral membrane protein with CBS domains n=4 T...   174   4e-42
UniRef50_B8J2R3 CBS domain containing protein n=3 Tax=Desulfovib...   174   4e-42
UniRef50_A6LDG3 Hemolysin-related protein n=23 Tax=Bacteroidales...   172   1e-41
UniRef50_A7C0B4 Mg2+ and Co2+ transporter CorC n=1 Tax=Beggiatoa...   171   2e-41
UniRef50_C2BV08 HCC HlyC/CorC family transporter n=3 Tax=Mobilun...   171   4e-41
UniRef50_C3WJU6 Magnesium and cobalt efflux protein corC n=15 Ta...   171   4e-41
UniRef50_A9B0K1 Putative uncharacterized protein n=1 Tax=Herpeto...   170   6e-41
UniRef50_Q5SKB4 Hemolysin-related protein n=3 Tax=Thermus RepID=...   169   1e-40
UniRef50_Q1K126 CBS domain protein n=2 Tax=Desulfuromonadales Re...   168   2e-40
UniRef50_A9WFQ5 CBS domain containing protein n=4 Tax=Chloroflex...   168   2e-40
UniRef50_B2S3N8 Hemolysin n=5 Tax=Spirochaetaceae RepID=B2S3N8_T...   167   4e-40
UniRef50_C8XF87 CBS domain containing protein n=11 Tax=Bacteria ...   167   5e-40
UniRef50_C1A944 Transporter n=1 Tax=Gemmatimonas aurantiaca T-27...   166   9e-40
UniRef50_D1B5K7 Putative uncharacterized protein n=1 Tax=Therman...   165   1e-39
UniRef50_B9L251 Magnesium and cobalt efflux protein corC n=1 Tax...   165   1e-39
UniRef50_C6BSI1 CBS domain containing protein n=2 Tax=Desulfovib...   164   3e-39
UniRef50_UPI0001BCCCA8 CBS domain-containing protein n=1 Tax=Aer...   164   3e-39
UniRef50_C6W2S8 CBS domain containing protein n=1 Tax=Dyadobacte...   164   4e-39
UniRef50_D1VUR6 CBS/transporter domain protein n=1 Tax=Peptoniph...   164   5e-39
UniRef50_C2MBP5 Gliding motility-associated protein GldE n=1 Tax...   164   5e-39
UniRef50_A8KYW4 CBS domain containing protein n=33 Tax=Actinomyc...   162   9e-39
UniRef50_A7HLR9 Putative uncharacterized protein n=1 Tax=Fervido...   162   1e-38
UniRef50_Q1AX40 Putative uncharacterized protein n=1 Tax=Rubroba...   162   2e-38
UniRef50_A1QYK9 Magnesium and cobalt efflux protein CorC n=21 Ta...   162   2e-38
UniRef50_A5CRB2 Conserved membrane protein n=4 Tax=Actinobacteri...   161   2e-38
UniRef50_B5YFP5 CBS domain protein n=1 Tax=Thermodesulfovibrio y...   160   3e-38
UniRef50_D1Y8K5 Putative transporter n=1 Tax=Pyramidobacter pisc...   160   4e-38
UniRef50_P67130 UPF0053 protein Rv2366c/MT2435 n=36 Tax=Actinomy...   160   5e-38
UniRef50_D1AFV9 Putative uncharacterized protein n=1 Tax=Sebalde...   160   5e-38
UniRef50_Q6ZUX1 cDNA FLJ43252 fis, clone HEART2006909 n=23 Tax=c...   160   6e-38
UniRef50_A6CBK3 Hemolysin protein n=1 Tax=Planctomyces maris DSM...   160   6e-38
UniRef50_Q1DCR5 CBS/transporter associated domain protein n=2 Ta...   159   7e-38
UniRef50_Q11NU6 Hemolysin-related protein, with CBS domain; glid...   159   8e-38
UniRef50_C0K042 Hemolysin-related protein n=1 Tax=uncultured bac...   159   9e-38
UniRef50_C6L9Q9 CBS domain protein n=6 Tax=Clostridiales RepID=C...   159   1e-37
UniRef50_C7GAD7 CBS domain protein n=9 Tax=Bacteria RepID=C7GAD7...   159   2e-37
UniRef50_C0W0A3 HCC HlyC/CorC family transporter n=1 Tax=Actinom...   158   2e-37
UniRef50_C9KMQ2 CBS domain protein n=1 Tax=Mitsuokella multacida...   157   3e-37
UniRef50_A1AQM4 CBS domain containing protein n=9 Tax=Desulfurom...   157   3e-37
UniRef50_C1ZDU6 CBS domain-containing protein n=1 Tax=Planctomyc...   157   4e-37
UniRef50_B8CXI7 Putative membrane CBS domain protein n=1 Tax=Hal...   157   4e-37
UniRef50_A3HUW6 Hemolysin-related protein, containing CBS domain...   157   5e-37
UniRef50_B5YET1 GldE n=2 Tax=Dictyoglomus RepID=B5YET1_DICT6          157   5e-37
UniRef50_Q1NMM8 CBS:Transporter-associated region n=2 Tax=Deltap...   157   5e-37
UniRef50_C0GM71 CBS domain containing protein n=1 Tax=Desulfonat...   157   5e-37
UniRef50_B3WFB2 Transport protein n=8 Tax=Lactobacillus RepID=B3...   157   5e-37
UniRef50_A6WDG0 CBS domain containing protein n=1 Tax=Kineococcu...   157   5e-37
UniRef50_Q6MCC0 Putative uncharacterized protein n=2 Tax=Parachl...   157   6e-37
UniRef50_C4V614 TlyC family hemolysin n=14 Tax=cellular organism...   156   9e-37
UniRef50_B8J8L5 CBS domain containing protein n=4 Tax=Anaeromyxo...   156   1e-36
UniRef50_C0W312 HCC HlyC/CorC family transporter n=1 Tax=Actinom...   155   1e-36
UniRef50_C9MVS3 CBS domain protein n=3 Tax=Fusobacteriaceae RepI...   154   2e-36
UniRef50_Q47RN3 CBS domain protein n=1 Tax=Thermobifida fusca YX...   154   3e-36
UniRef50_B8G2E5 Putative uncharacterized protein n=3 Tax=Clostri...   154   4e-36
UniRef50_Q73QX2 CBS domain protein n=1 Tax=Treponema denticola R...   153   6e-36
UniRef50_A0JX40 CBS domain containing protein n=4 Tax=Micrococca...   153   6e-36
UniRef50_B4CWQ9 CBS domain containing protein n=2 Tax=Verrucomic...   153   7e-36
UniRef50_D2NT77 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NT...   153   7e-36
UniRef50_C5VQE4 CBS domain integral membrane protein n=9 Tax=Clo...   152   9e-36
UniRef50_C5PXG9 TlyC family hemolysin n=5 Tax=Sphingobacteriales...   152   1e-35
UniRef50_A9IMV8 Hemolysin n=5 Tax=Bartonella RepID=A9IMV8_BART1       152   1e-35
UniRef50_C9L5N7 Hemolysin-related protein n=1 Tax=Blautia hansen...   152   2e-35
UniRef50_D1AH17 Putative uncharacterized protein n=1 Tax=Sebalde...   152   2e-35
UniRef50_D1Y9A3 CBS domain protein n=3 Tax=Propionibacterium acn...   151   2e-35
UniRef50_C7LQH5 Putative uncharacterized protein n=1 Tax=Desulfo...   151   2e-35
UniRef50_D1C4W4 Putative uncharacterized protein n=1 Tax=Sphaero...   151   2e-35
UniRef50_Q74EV6 CBS domain protein n=9 Tax=Desulfuromonadales Re...   151   2e-35
UniRef50_UPI000050F785 CBS domain-containing protein n=1 Tax=Bre...   151   3e-35
UniRef50_C3J7T2 CBS domain pair n=4 Tax=Bacteria RepID=C3J7T2_9PORP   151   3e-35
UniRef50_D2RIW5 CBS domain containing protein n=2 Tax=Acidaminoc...   151   3e-35
UniRef50_B8I559 Putative uncharacterized protein n=1 Tax=Clostri...   150   4e-35
UniRef50_A9HIL4 CBS domain containing protein n=11 Tax=Acetobact...   150   6e-35
UniRef50_A0M7C1 Gliding motility protein GldE n=23 Tax=Bacteroid...   150   6e-35
UniRef50_A3ZXV1 Hemolysin protein n=1 Tax=Blastopirellula marina...   150   7e-35
UniRef50_Q01WS1 Putative uncharacterized protein n=1 Tax=Candida...   149   1e-34
UniRef50_C6W3X5 Putative uncharacterized protein n=1 Tax=Dyadoba...   149   1e-34
UniRef50_Q1IKR3 CBS domain protein n=1 Tax=Candidatus Koribacter...   149   2e-34
UniRef50_C7IJK2 CBS domain containing protein n=5 Tax=Firmicutes...   148   2e-34
UniRef50_B7RC07 CBS domain integral membrane protein n=5 Tax=The...   148   2e-34
UniRef50_A9F240 Conserved hypothetical membrane protein n=1 Tax=...   148   2e-34
UniRef50_Q2FTJ8 Putative uncharacterized protein n=4 Tax=Methano...   148   2e-34
UniRef50_D2RB94 CBS domain protein n=1 Tax=Gardnerella vaginalis...   147   3e-34
UniRef50_C1TQS8 CBS domain-containing protein n=2 Tax=Synergista...   147   4e-34
UniRef50_C2ECT1 Hemolysin n=1 Tax=Lactobacillus ruminis ATCC 256...   147   4e-34
UniRef50_B8JAD7 Putative uncharacterized protein n=4 Tax=Anaerom...   147   5e-34
UniRef50_A0LG68 CBS domain containing protein n=1 Tax=Syntrophob...   147   5e-34
UniRef50_A0PYY8 Integral membrane protein with CBS domains n=15 ...   147   5e-34
UniRef50_C7NH44 CBS domain-containing protein n=3 Tax=Actinomyce...   147   6e-34
UniRef50_B0VIA5 CBS domain protein (Modular protein) n=1 Tax=Can...   146   7e-34
UniRef50_C4GBW1 Putative uncharacterized protein n=1 Tax=Shuttle...   146   9e-34
UniRef50_C8NIX4 Hemolysin n=3 Tax=Firmicutes RepID=C8NIX4_9LACT       145   1e-33
UniRef50_A9NGP1 Putative hemolysin-related protein n=2 Tax=Bacte...   145   1e-33
UniRef50_A9KQ60 Putative uncharacterized protein n=8 Tax=Clostri...   145   1e-33
UniRef50_B2V0W8 Putative membrane CBS domain protein n=14 Tax=Cl...   145   1e-33
UniRef50_C6PR79 CBS domain containing protein n=10 Tax=Clostridi...   145   1e-33
UniRef50_Q1IYV3 CBS domain-containing protein DUF21 n=4 Tax=Bact...   145   1e-33
UniRef50_C0QRS4 CBS/transporter-associated domain protein n=5 Ta...   145   1e-33
UniRef50_C6J8N4 Putative uncharacterized protein n=1 Tax=Ruminoc...   145   1e-33
UniRef50_C1F7E2 CBS/transporter domain protein n=1 Tax=Acidobact...   145   2e-33
UniRef50_C6HVJ5 Putative uncharacterized protein n=1 Tax=Leptosp...   145   2e-33
UniRef50_C8VVX2 Putative uncharacterized protein n=2 Tax=Clostri...   145   2e-33
UniRef50_A6DQ65 CBS:Transporter-associated region n=1 Tax=Lentis...   145   2e-33
UniRef50_A8U4Z8 Hemolysin n=1 Tax=Carnobacterium sp. AT7 RepID=A...   144   3e-33
UniRef50_B8G6A7 Putative uncharacterized protein n=3 Tax=Chlorof...   144   3e-33
UniRef50_C4Z1L1 Putative hemolysin n=2 Tax=Bacteria RepID=C4Z1L1...   144   3e-33
UniRef50_C6J7K3 Putative uncharacterized protein n=2 Tax=Bacilla...   144   4e-33
UniRef50_A5UY55 Putative uncharacterized protein n=3 Tax=Chlorof...   144   4e-33
UniRef50_B9KAC3 Hemolysin-related protein n=1 Tax=Thermotoga nea...   144   4e-33
UniRef50_A7BE68 Putative uncharacterized protein n=1 Tax=Actinom...   144   5e-33
UniRef50_D1AX34 CBS domain containing protein n=1 Tax=Streptobac...   143   5e-33
UniRef50_UPI000196CD6F hypothetical protein CATMIT_02806 n=1 Tax...   143   7e-33
UniRef50_C4LJQ9 Transporter of the HlyC/CorC family n=4 Tax=Cory...   143   7e-33
UniRef50_C0QYZ5 Hemolysin protein n=2 Tax=Brachyspira RepID=C0QY...   143   7e-33
UniRef50_A3VQ34 CBS domain protein n=1 Tax=Parvularcula bermuden...   143   7e-33
UniRef50_A7HZ85 CBS domain containing protein n=1 Tax=Parvibacul...   143   9e-33
UniRef50_C0CHP0 Putative uncharacterized protein n=1 Tax=Blautia...   143   9e-33
UniRef50_C4G6D4 Putative uncharacterized protein n=1 Tax=Abiotro...   142   1e-32
UniRef50_Q5HR32 CBS domain protein n=18 Tax=Bacillales RepID=Q5H...   142   1e-32
UniRef50_B5Y9X2 CBS domain protein n=1 Tax=Coprothermobacter pro...   142   1e-32
UniRef50_B3DSC1 Hemolysin-like protein n=7 Tax=Bifidobacteriacea...   142   2e-32
UniRef50_D2LWG5 Putative uncharacterized protein n=3 Tax=Bacillu...   142   2e-32
UniRef50_A7VIV6 Putative uncharacterized protein n=2 Tax=Clostri...   142   2e-32
UniRef50_D1BUW5 CBS domain containing protein n=3 Tax=Micrococci...   141   2e-32
UniRef50_A5V8Y4 CBS domain containing protein n=9 Tax=Sphingomon...   141   2e-32
UniRef50_B3QAC3 CBS domain containing protein n=15 Tax=Rhizobial...   141   2e-32
UniRef50_A9KLG3 Putative uncharacterized protein n=1 Tax=Clostri...   141   3e-32
UniRef50_A0LRV3 Putative uncharacterized protein n=1 Tax=Acidoth...   141   3e-32
UniRef50_A5ZVW9 Putative uncharacterized protein n=1 Tax=Ruminoc...   141   3e-32
UniRef50_D2BD19 Putative uncharacterized protein n=1 Tax=Strepto...   141   3e-32
UniRef50_C7MLQ1 CBS domain-containing protein n=8 Tax=Coriobacte...   140   4e-32
UniRef50_B2V0V1 CBS/transporter domain protein n=18 Tax=Clostrid...   140   4e-32
UniRef50_D2QA49 Hemolysins-like protein containing CBS domains n...   140   5e-32
UniRef50_C1A9X1 Hypothetical membrane protein n=1 Tax=Gemmatimon...   140   5e-32
UniRef50_B1I646 Putative uncharacterized protein n=1 Tax=Candida...   140   5e-32
UniRef50_Q01P08 CBS domain containing protein n=1 Tax=Candidatus...   140   7e-32
UniRef50_A9VF50 Putative uncharacterized protein n=6 Tax=Bacillu...   140   7e-32
UniRef50_D2RTA7 Putative uncharacterized protein n=3 Tax=Haloter...   139   9e-32
UniRef50_B0A8E0 Putative uncharacterized protein n=1 Tax=Clostri...   139   9e-32
UniRef50_B9XIF8 Putative uncharacterized protein n=1 Tax=bacteri...   139   9e-32
UniRef50_Q93NC4 Hemolysin TlyC n=3 Tax=Cystobacterineae RepID=Q9...   139   1e-31
UniRef50_A0RW86 Hemolysin n=4 Tax=Thaumarchaeota RepID=A0RW86_CENSY   139   1e-31
UniRef50_B6JNY8 Hemolysin domain-containing protein n=23 Tax=Cam...   139   1e-31
UniRef50_C5VDL5 CBS domain containing protein n=3 Tax=Corynebact...   139   1e-31
UniRef50_D2QT15 Gliding motility-associated protein GldE n=1 Tax...   139   2e-31
UniRef50_C7DFD3 CBS domain protein n=6 Tax=Rhodobacteraceae RepI...   139   2e-31
UniRef50_B6FN86 Putative uncharacterized protein n=2 Tax=Clostri...   138   2e-31
UniRef50_B7GEW2 Hemolysin related protein containing CBS domains...   138   2e-31
UniRef50_Q1IKR7 Putative uncharacterized protein n=1 Tax=Candida...   138   3e-31
UniRef50_C7MD87 CBS domain-containing protein n=1 Tax=Brachybact...   137   3e-31
UniRef50_C7RPW0 Putative uncharacterized protein n=1 Tax=Candida...   137   3e-31
UniRef50_B8ETG8 CBS domain containing protein n=2 Tax=Beijerinck...   137   5e-31
UniRef50_C1YNF1 CBS domain-containing protein n=1 Tax=Nocardiops...   137   5e-31
UniRef50_D1N3F2 Putative uncharacterized protein n=1 Tax=Victiva...   137   5e-31
UniRef50_UPI0001973384 hypothetical protein ClM62_01605 n=1 Tax=...   137   5e-31
UniRef50_D0WN55 Integral membrane transporter with CBS domain n=...   137   6e-31
UniRef50_A4EBJ7 Putative uncharacterized protein n=1 Tax=Collins...   136   7e-31
UniRef50_Q253J4 Hemolysin n=3 Tax=Chlamydophila RepID=Q253J4_CHLFF    136   9e-31
UniRef50_C7NDD7 CBS domain containing protein n=3 Tax=Leptotrich...   136   1e-30
UniRef50_Q0EWJ5 CBS:Transporter-associated region n=1 Tax=Maripr...   136   1e-30
UniRef50_A7VCA4 Putative uncharacterized protein n=2 Tax=Clostri...   136   1e-30
UniRef50_C4GB29 Putative uncharacterized protein n=1 Tax=Shuttle...   135   1e-30
UniRef50_A4J4V5 Putative uncharacterized protein n=1 Tax=Desulfo...   135   1e-30
UniRef50_C3L2Y2 Transporter, HlyC/CorC family n=26 Tax=Bacteria ...   135   1e-30
UniRef50_Q3ZYX1 Probable hemolysin-related protein n=5 Tax=Dehal...   135   1e-30
UniRef50_Q164J1 CBS domain protein n=37 Tax=Rhodobacterales RepI...   135   1e-30
UniRef50_B0R9W4 Hemolysin homolog n=3 Tax=cellular organisms Rep...   135   1e-30
UniRef50_B3QWB4 Transporter-associated region n=1 Tax=Chloroherp...   135   1e-30
UniRef50_C9RLZ8 CBS domain containing protein n=1 Tax=Fibrobacte...   135   2e-30
UniRef50_C7RN87 Putative uncharacterized protein n=1 Tax=Candida...   135   2e-30
UniRef50_C1XJH4 CBS domain-containing protein n=1 Tax=Meiothermu...   135   2e-30
UniRef50_C7R522 CBS domain containing protein n=1 Tax=Jonesia de...   135   2e-30
UniRef50_B0NK60 Putative uncharacterized protein n=1 Tax=Clostri...   135   2e-30
UniRef50_B0PAE4 Putative uncharacterized protein n=2 Tax=Clostri...   135   2e-30
UniRef50_UPI00016C05A3 CBS/transporter-associated domain protein...   135   2e-30
UniRef50_Q041Z4 Hemolysin-like protein with CBS domains n=27 Tax...   135   2e-30
UniRef50_C7HS55 Transporter n=3 Tax=Anaerococcus RepID=C7HS55_9FIRM   135   2e-30
UniRef50_B6FYX0 Putative uncharacterized protein n=1 Tax=Clostri...   134   2e-30
UniRef50_B0MCI7 Putative uncharacterized protein n=2 Tax=Clostri...   134   3e-30
UniRef50_A2SSZ1 Putative uncharacterized protein n=1 Tax=Methano...   134   3e-30
UniRef50_Q2NIR0 Hymolysin-related protein n=5 Tax=Candidatus Phy...   134   3e-30
UniRef50_C1D3R1 Putative hemolysin; putative membrane protein n=...   134   3e-30
UniRef50_C9KJP9 CBS domain protein n=3 Tax=Veillonellaceae RepID...   134   3e-30
UniRef50_C4ZBH2 Hemolysin n=1 Tax=Eubacterium rectale ATCC 33656...   134   5e-30
UniRef50_Q0G3C6 Putative uncharacterized protein n=2 Tax=Auranti...   134   5e-30
UniRef50_Q1J8A0 Magnesium and cobalt efflux protein corC n=129 T...   133   6e-30
UniRef50_B0MNL0 Putative uncharacterized protein n=1 Tax=Eubacte...   133   6e-30
UniRef50_Q7NJJ9 Glr1833 protein n=2 Tax=Cyanobacteria RepID=Q7NJ...   133   7e-30
UniRef50_A8SE58 Putative uncharacterized protein n=2 Tax=Bacteri...   133   7e-30
UniRef50_C6W2P9 Transporter-associated region n=1 Tax=Dyadobacte...   133   8e-30
UniRef50_A5PBT5 Hemolysin n=1 Tax=Erythrobacter sp. SD-21 RepID=...   133   9e-30
UniRef50_C5EUB4 Membrane-anchored CBS domain-containing protein-...   133   9e-30
UniRef50_UPI0001C36BB6 hypothetical protein ChatD1_07246 n=1 Tax...   132   1e-29
UniRef50_O07589 UPF0053 protein yhdT n=119 Tax=Bacillales RepID=...   132   1e-29
UniRef50_Q3KLS8 CorC n=10 Tax=Chlamydiaceae RepID=Q3KLS8_CHLTA        132   1e-29
UniRef50_B4U6L1 CBS domain containing protein n=1 Tax=Hydrogenob...   132   2e-29
UniRef50_B9DK54 Predicted membrane protein with CBS domains n=54...   132   2e-29
UniRef50_C5CCC5 CBS domain-containing protein n=1 Tax=Micrococcu...   132   2e-29
UniRef50_A8GUH1 Possible hemolysin C n=15 Tax=Rickettsia RepID=H...   132   2e-29
UniRef50_C6D831 Putative uncharacterized protein n=6 Tax=Bacilla...   132   2e-29
UniRef50_C6LCF2 CBS domain protein n=1 Tax=Bryantella formatexig...   132   2e-29
UniRef50_C9LMB7 Putative transporter n=1 Tax=Dialister invisus D...   131   2e-29
UniRef50_A0L637 Putative uncharacterized protein n=5 Tax=cellula...   131   3e-29
UniRef50_C5SJL8 CBS domain containing protein n=1 Tax=Asticcacau...   131   3e-29
UniRef50_C9LYN4 CBS domain protein n=2 Tax=Selenomonas RepID=C9L...   131   3e-29
UniRef50_UPI0000510515 magnesium and cobalt efflux protein n=1 T...   131   3e-29
UniRef50_A6CIW3 Probable hemolysin n=2 Tax=Bacillus RepID=A6CIW3...   131   3e-29

>UniRef50_Q9KTE3 Magnesium and cobalt efflux protein corC n=42 Tax=Proteobacteria
           RepID=CORC_VIBCH
          Length = 291

 Score =  373 bits (957), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 189/283 (66%), Positives = 234/283 (82%), Gaps = 2/283 (0%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M++DNS +S+  S +K FF  L SQLF GEPK+R EL+ +IRDS  NDLID DTRDMLEG
Sbjct: 1   MNEDNSQNSEGPS-RKSFFERL-SQLFQGEPKDRQELVDVIRDSEVNDLIDHDTRDMLEG 58

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           VM+IA+ RVRDIMIPRSQM+T+ R   LD  + ++ ++ HSR+PVISEDKDH+EGIL+AK
Sbjct: 59  VMEIAEMRVRDIMIPRSQMVTIDRTHNLDALVAIMTDAQHSRYPVISEDKDHVEGILLAK 118

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL ++ S+   F++ +V+R AVVVPESKRVDR+LKEFR +RYHMAIV+DEFGGVSGLVT
Sbjct: 119 DLLKYLGSNCAPFNIQEVIRPAVVVPESKRVDRLLKEFREERYHMAIVVDEFGGVSGLVT 178

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IEDILE IVG+IEDE+D+E+  D RQLS+HT++V+AL +IEDFN  FGT FSDEEVDT+G
Sbjct: 179 IEDILEEIVGDIEDEFDDEEQKDIRQLSKHTFSVKALTTIEDFNHTFGTKFSDEEVDTVG 238

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           GLVM AFGHLPARGE +DI GY FKV  ADSRR++ + V +PD
Sbjct: 239 GLVMTAFGHLPARGEVVDIAGYNFKVTAADSRRVVALQVTVPD 281


>UniRef50_Q9CM13 Magnesium and cobalt efflux protein corC n=264
           Tax=Gammaproteobacteria RepID=CORC_PASMU
          Length = 300

 Score =  358 bits (919), Expect = 1e-97,   Method: Compositional matrix adjust.
 Identities = 181/280 (64%), Positives = 231/280 (82%), Gaps = 1/280 (0%)

Query: 5   NSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDI 64
           N++S+++   KK FF  L  + F GE KNR+EL+ +IRDS QN+LID++TR+M+EGVM+I
Sbjct: 8   NTYSTES-HQKKSFFQSLFGRFFQGELKNREELVEVIRDSEQNELIDQNTREMIEGVMEI 66

Query: 65  ADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP 124
           A+ RVRDIMIPRSQ++ +  +Q LD CLD II SAHSRFPVI++++D+I GIL AKDLL 
Sbjct: 67  AELRVRDIMIPRSQIVFIHTDQNLDSCLDTIIVSAHSRFPVITDERDNIAGILHAKDLLR 126

Query: 125 FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDI 184
           F+RS+AE F +  +LR AV+VPESKRVDRMLK+FRS+R+HMAIV+DEFG VSGLVTIEDI
Sbjct: 127 FLRSNAEEFDLMPLLRPAVIVPESKRVDRMLKDFRSERFHMAIVVDEFGAVSGLVTIEDI 186

Query: 185 LELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVM 244
           LE IVG+IEDE+DEE+ ++ RQLSRHT+ VRAL  IEDFN+ F THF+DEEVDTIGG+VM
Sbjct: 187 LEQIVGDIEDEFDEEEIVNIRQLSRHTYAVRALTDIEDFNQQFNTHFADEEVDTIGGVVM 246

Query: 245 QAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           QAFG+LP RGE I I+   FKV  ADSRR+IQ+ + + D+
Sbjct: 247 QAFGYLPKRGEEITIENIGFKVTSADSRRLIQLRITVTDE 286


>UniRef50_Q7VRA4 Haemolysin-related protein n=2 Tax=Candidatus Blochmannia
           RepID=Q7VRA4_BLOFL
          Length = 291

 Score =  342 bits (877), Expect = 8e-93,   Method: Compositional matrix adjust.
 Identities = 163/283 (57%), Positives = 221/283 (78%), Gaps = 2/283 (0%)

Query: 4   DNSHSSDTISN--KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGV 61
           +N++  ++I +  KK FF+L+L  LF    +NR++LL LIRD  +N LID DT+DMLEGV
Sbjct: 2   NNNYLEESIHSVRKKNFFALILKHLFRENFRNRNDLLNLIRDFEKNALIDSDTKDMLEGV 61

Query: 62  MDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKD 121
           ++I +Q+VRDIMIPRSQ+I LK  Q+ DE L +II+S+HSRFPV++ED D I+GIL+AKD
Sbjct: 62  LEIVEQKVRDIMIPRSQIIFLKNTQSWDEQLSIIIQSSHSRFPVLNEDLDQIKGILIAKD 121

Query: 122 LLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
           LLP +    + +++ ++LR A+VVPE+K VDRMLKEFR+Q  HMAIVIDEFG +SG++TI
Sbjct: 122 LLPLILKKNQPYNIGQILRPAMVVPENKGVDRMLKEFRAQHCHMAIVIDEFGSMSGIITI 181

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGG 241
           EDILELIVG IEDEYD ++D +  Q++  T+ + AL  +E+FN  F T+F +EE+DTIGG
Sbjct: 182 EDILELIVGNIEDEYDNKNDCNIYQVNHRTFLINALTPVEEFNIKFNTNFYNEEIDTIGG 241

Query: 242 LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
            VMQ FGHLPARGE+IDI GY FK+ + D+ RIIQ+ V+IP +
Sbjct: 242 FVMQTFGHLPARGESIDISGYIFKITVTDNHRIIQLLVQIPKN 284


>UniRef50_Q48DN5 Metal ion transporter, putative n=16 Tax=Proteobacteria
           RepID=Q48DN5_PSE14
          Length = 280

 Score =  280 bits (717), Expect = 3e-74,   Method: Compositional matrix adjust.
 Identities = 141/268 (52%), Positives = 194/268 (72%), Gaps = 1/268 (0%)

Query: 8   SSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           S D  SN +  +   L+Q F  EPKNR ELL L+R++ QN L+D +   ++EG + +AD 
Sbjct: 2   SEDRSSNGQKSWLGKLTQAFVHEPKNRQELLELLREAHQNKLLDSEALAIVEGAIQVADL 61

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF-M 126
           +VRDIM+PRSQMI++K  QT  E L  +I++AHSR+PVI E  D + G+L+AKDLLP  +
Sbjct: 62  QVRDIMVPRSQMISIKATQTPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAKDLLPLIL 121

Query: 127 RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
           ++D ++  + K+LR A  VPESKR++ +L+EFR+   HMAIVIDE+GGV+GLVTIED+LE
Sbjct: 122 KADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVLE 181

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            IVG+IEDE+D E+D   + L    + V+AL  +E+FNE F + FSD+E DT+GGLVM A
Sbjct: 182 QIVGDIEDEHDVEEDSYIKPLPSGDFLVKALTPVENFNEFFDSAFSDDEFDTVGGLVMNA 241

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRI 274
           FGHLP R E  +I  Y+F++  ADSRRI
Sbjct: 242 FGHLPKRNEITEIGAYRFRILSADSRRI 269


>UniRef50_A4VQY6 Metal ion transporter, putative n=2 Tax=Gammaproteobacteria
           RepID=A4VQY6_PSEU5
          Length = 280

 Score =  273 bits (697), Expect = 6e-72,   Method: Compositional matrix adjust.
 Identities = 139/275 (50%), Positives = 194/275 (70%), Gaps = 7/275 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S     IS +K +   + +Q F  EPKNR ELL ++R++ QN L+D +   ++EG
Sbjct: 1   MSEDRS-----ISGQKTWLERI-TQAFAHEPKNRQELLEILREAHQNKLLDNEALAIVEG 54

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            + +AD +VRDIM+PRSQ+I++K +Q+  E L  II +AHSR+PV+ E  D + G+L+AK
Sbjct: 55  AIQVADLQVRDIMVPRSQVISIKADQSPREFLPAIIAAAHSRYPVVGESLDEVIGVLLAK 114

Query: 121 DLLPF-MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLLP  ++ D + F +  +LR A  VPESKR++ +L+EFR+   HMAIVIDE+GGV+GLV
Sbjct: 115 DLLPLILKEDQQNFDIKDLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLV 174

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVG+IEDE+D E+D   R L    + V+AL  I+ FNE FG+ F D+E DT+
Sbjct: 175 TIEDVLEQIVGDIEDEHDVEEDSYIRPLPSGDFLVKALTPIDSFNEYFGSAFPDDEFDTV 234

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
            GLVM  FGHLP R E  +IDG++ +V  ADSRR+
Sbjct: 235 AGLVMSTFGHLPKRNEVTEIDGFRVRVLNADSRRV 269


>UniRef50_Q1YQV9 Magnesium and cobalt efflux protein CorC n=1 Tax=gamma
           proteobacterium HTCC2207 RepID=Q1YQV9_9GAMM
          Length = 279

 Score =  260 bits (665), Expect = 3e-68,   Method: Compositional matrix adjust.
 Identities = 121/257 (47%), Positives = 182/257 (70%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           +S +F   P++ +++  ++R +    +ID     ++EG + ++DQ+ R+IMIPRSQM+ +
Sbjct: 18  ISDVFSQTPRSSEDVADILRSAENESIIDASVLQIMEGALKVSDQQAREIMIPRSQMVII 77

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQA 142
             + +L++ L V+I S HSRFPV+ E  D I+GIL+AK++LP + S  E+F +  +LR A
Sbjct: 78  DDDFSLEQVLKVVISSQHSRFPVVGESSDDIKGILLAKEMLPLLLSGNESFDLKALLRPA 137

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
            ++PESKR++ +L+EFR QRYHMAIV+DE+GGVSGL+TIEDILE IVGEIEDE DE ++ 
Sbjct: 138 TIIPESKRLNVLLQEFREQRYHMAIVVDEYGGVSGLLTIEDILEEIVGEIEDETDEHEEA 197

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGY 262
             +  +  ++ V A+A + +FNE F    +D+E DT+GGLV+ AFG LP   E+ID DG+
Sbjct: 198 PIKATTSGSFNVEAIAEVSEFNEFFDVGLADDEFDTVGGLVLHAFGRLPEINESIDFDGF 257

Query: 263 QFKVAMADSRRIIQVHV 279
            FKV   D+R+I Q+ V
Sbjct: 258 TFKVTDGDNRKITQLEV 274


>UniRef50_B5JWG7 CBS domain containing protein n=3 Tax=Gammaproteobacteria
           RepID=B5JWG7_9GAMM
          Length = 298

 Score =  259 bits (662), Expect = 8e-68,   Method: Compositional matrix adjust.
 Identities = 131/271 (48%), Positives = 186/271 (68%), Gaps = 2/271 (0%)

Query: 23  LSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT 81
           L Q F G +P+N D++L ++RD+ +  L D     M+EGV ++ + RVRDIMIPRS M  
Sbjct: 24  LGQAFGGNDPQNLDQILEVLRDAQERGLFDLHALAMVEGVFEVTEMRVRDIMIPRSHMTV 83

Query: 82  LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQ 141
           L++     + L+++ ES HSRFPVI+ D+D + G+L+AKD+L +     E F++D +LRQ
Sbjct: 84  LEQGADFGDVLNILTESGHSRFPVIAGDRDELVGVLLAKDVLKYA-GRPEEFALDDILRQ 142

Query: 142 AVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD 201
            V++PESKR+  +L EFRS R H+A+V+DE+GGVSGLVTIED+LE+IVGEI+DE+D E+D
Sbjct: 143 VVIIPESKRLITLLNEFRSSRNHLAMVVDEYGGVSGLVTIEDVLEVIVGEIDDEHDSEED 202

Query: 202 IDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDG 261
              R   +  +TV AL  IE+FN  F T  SDE+ DTIGG VM+  GH+P RGE ++ +G
Sbjct: 203 HYIRPHRKGHYTVHALTEIEEFNAFFKTTLSDEDADTIGGYVMRLLGHVPKRGEQVESEG 262

Query: 262 YQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
             F V  ADSRRI ++ V   +   +P + E
Sbjct: 263 ILFTVLGADSRRIYRLKVTTEESLDEPTMAE 293


>UniRef50_B9ZL46 CBS domain containing protein n=2 Tax=Gammaproteobacteria
           RepID=B9ZL46_9GAMM
          Length = 311

 Score =  256 bits (655), Expect = 5e-67,   Method: Compositional matrix adjust.
 Identities = 133/267 (49%), Positives = 190/267 (71%), Gaps = 6/267 (2%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           +P  R EL+  +RD+   +L+D +   MLEGV+++AD +VRDIMIPR+QM  ++R+  L 
Sbjct: 28  DPATRRELIETLRDAHGRELVDPEALTMLEGVLNVADMQVRDIMIPRAQMEVVRRDARLS 87

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPES 148
           E L  ++ SAHSR PV+ + +D + G+L+AKDLL F    D  AF M ++LR AV VPES
Sbjct: 88  EFLPDVVASAHSRLPVVGDHRDEVVGVLLAKDLLRFFGEPDDAAFDMQEILRPAVFVPES 147

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           KR++ +LKEFR  R HMAIV+DE+GGV+GLVTIED+LE IVGEIEDE+D ED +   Q+ 
Sbjct: 148 KRLNVLLKEFRLSRNHMAIVVDEYGGVAGLVTIEDVLEQIVGEIEDEHDVEDYLT--QIM 205

Query: 209 RHT---WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
           +H    +T++AL  +E+FN  F T +S+++ DTIGGLV+  FGH+P RGE I IDG +F+
Sbjct: 206 QHPGGRYTIKALTPMEEFNAYFQTAYSEDDFDTIGGLVLSHFGHVPRRGEQIVIDGMRFR 265

Query: 266 VAMADSRRIIQVHVKIPDDSPQPKLDE 292
           V  AD+RR+  + +++P+    P  D+
Sbjct: 266 VLRADNRRLHLLEMRLPEPDVAPASDD 292


>UniRef50_Q5ZVK1 Mg2+ and Co2+ transporter CorC n=6 Tax=Legionella
           RepID=Q5ZVK1_LEGPH
          Length = 296

 Score =  254 bits (648), Expect = 3e-66,   Method: Compositional matrix adjust.
 Identities = 120/252 (47%), Positives = 172/252 (68%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           L Q   GEP+N++EL++L+RD+    LI+ +T  M+EG +  +  RVRDIM+P++QM+ +
Sbjct: 25  LKQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRVRDIMLPKNQMVCI 84

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQA 142
            ++      + ++ ++ HSRFPV  E+ D + GIL AKDLL +   + E+F +  + RQ 
Sbjct: 85  NKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPENMESFDLLDICRQV 144

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
             VPES+R+D +L EFRS R HMAIV+DE+G VSG VTIEDI+E I+G+IEDE+D ++D 
Sbjct: 145 TFVPESRRLDSLLSEFRSNRNHMAIVVDEYGEVSGFVTIEDIIEQIIGDIEDEFDIDEDA 204

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGY 262
             +    H + ++A   IE+FNE     FSDE  DTIGG+V+  FG+LP RGE I ID +
Sbjct: 205 YIKTHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGIVLNKFGYLPQRGEVIIIDDF 264

Query: 263 QFKVAMADSRRI 274
           +FKV  ADSRRI
Sbjct: 265 EFKVLNADSRRI 276


>UniRef50_B8KMV1 Magnesium and cobalt efflux protein CorC n=3 Tax=unclassified
           Gammaproteobacteria RepID=B8KMV1_9GAMM
          Length = 282

 Score =  253 bits (646), Expect = 5e-66,   Method: Compositional matrix adjust.
 Identities = 143/283 (50%), Positives = 198/283 (69%), Gaps = 5/283 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MSDD + + +   +  G     ++Q F  EP+ R++L  +++ + +ND+I+ED+  +++G
Sbjct: 1   MSDDRNGNGNEEKSLLG----RIAQAFSSEPRTREDLQQILQLAMENDIIEEDSLSIIDG 56

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            M ++  + RDIM+PR QM+ +K   TL+E L  I ES HSR+PVI E  D I GIL+ K
Sbjct: 57  AMQVSGMQARDIMVPRPQMVVIKSESTLEEVLQHISESKHSRYPVIGESPDDILGILLVK 116

Query: 121 DLLP-FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLLP  +  D E F + ++LRQ+VVVPESKR++ +L+EFR  R HMAIVIDE+GGV+GLV
Sbjct: 117 DLLPQILSEDRENFDIRQLLRQSVVVPESKRLNVLLREFRENRNHMAIVIDEYGGVAGLV 176

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVGEIEDE DEE+D   R++S   + VRAL  IEDFN+ F   FSD+E DTI
Sbjct: 177 TIEDVLEEIVGEIEDETDEEEDQFIRRISDDDFFVRALTPIEDFNDYFDVAFSDDEFDTI 236

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           GGLVM AFGH+P R E   I+G++FKV  AD R+I  + ++ P
Sbjct: 237 GGLVMHAFGHMPTRNEITHIEGFEFKVINADQRKIHSLRLRPP 279


>UniRef50_D0KZZ4 CBS domain containing protein n=1 Tax=Halothiobacillus neapolitanus
           c2 RepID=D0KZZ4_HALNC
          Length = 299

 Score =  248 bits (633), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 125/272 (45%), Positives = 178/272 (65%), Gaps = 5/272 (1%)

Query: 8   SSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           SS + S++ G+F+ L  Q    + K+  ++L + + + +  +I   T  +++ V++  D 
Sbjct: 5   SSPSRSDEPGWFARLRQQWCISQVKSCSDILTVAKAAAEKQIIPHSTASLIDSVLEFHDS 64

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
           RVRD+MIPR QM  +    TL + L  I E+ HSR+PVI E++D I GIL+ K+LL F  
Sbjct: 65  RVRDVMIPRGQMDVINITSTLPQILSEIAETGHSRYPVILENRDEITGILLVKELLHFYA 124

Query: 128 S-----DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIE 182
                 D   F++   +R A+ VPESKR+D +L EFR  R HMAIV+DEFGGV+GLVTIE
Sbjct: 125 GTPSEEDIAGFTLKNHIRSALYVPESKRLDVLLAEFRLTRTHMAIVLDEFGGVAGLVTIE 184

Query: 183 DILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGL 242
           D+LE IVG+I+DEYD  + +  R+ S + +TVRAL  I++FN  FGT FSD+E DTIGG 
Sbjct: 185 DVLEEIVGDIDDEYDTAEPVHIREQSANRFTVRALTPIDEFNAHFGTDFSDDEYDTIGGF 244

Query: 243 VMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
           +    GHLP RGE + + GY+FK+  AD RR+
Sbjct: 245 ITHELGHLPRRGEVVCVGGYEFKILGADKRRL 276


>UniRef50_A8PND0 Magnesium and cobalt efflux protein CorC n=1 Tax=Rickettsiella
           grylli RepID=A8PND0_9COXI
          Length = 289

 Score =  247 bits (630), Expect = 4e-64,   Method: Compositional matrix adjust.
 Identities = 124/275 (45%), Positives = 185/275 (67%), Gaps = 6/275 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           N++ +FS     +F   PKNR +L+ L+  + Q +L++     MLEGV+ I+D +VRDIM
Sbjct: 15  NRQSWFSRF--NVFKQAPKNRKQLIELLHYAKQRNLLNSQALKMLEGVLQISDSQVRDIM 72

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IP +++  +     L E L ++IESAHSRFPVI++++  I G+LMAKDLL +       F
Sbjct: 73  IPHAKITAISAKAPLSEILPLVIESAHSRFPVINDERQVI-GLLMAKDLLKYNPLSQNDF 131

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           ++  +LR  V +PESKR+D +LKEF+ + YHMAIV+DE+G  SGLVTIED+LE IVGEIE
Sbjct: 132 NIHTILRPVVFIPESKRLDSLLKEFQRKHYHMAIVVDEYGAASGLVTIEDVLEEIVGEIE 191

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DE+D +++I  ++ + H + V+A+  IE FN  F +H   ++ DTIGG++   FG+LP R
Sbjct: 192 DEHDTDEEIFIQEQTPHQFIVKAIMPIEAFNAFFNSHLETDQFDTIGGVIANRFGYLPKR 251

Query: 254 GETIDIDGYQFKVAMADSR--RIIQVHVKIPDDSP 286
           G +  I  + FKV  AD+R  R++QV ++ P + P
Sbjct: 252 GASTTIYPFHFKVLRADNRVIRLLQVTIE-PVNKP 285


>UniRef50_C7RRT5 CBS domain containing protein n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RRT5_9PROT
          Length = 281

 Score =  247 bits (630), Expect = 4e-64,   Method: Compositional matrix adjust.
 Identities = 134/282 (47%), Positives = 191/282 (67%), Gaps = 4/282 (1%)

Query: 9   SDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
           S + S K GFF  L S L   EP++R++L+ L+  + Q  L+D D   + EG +  ++  
Sbjct: 3   SSSPSGKPGFFERL-SSLLVREPEDREQLVQLLHAAHQRKLLDADALSITEGALAASEMI 61

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS 128
           VR++M+PR QM  +    TLD+ +D +  +AHSRFPVI+ D+DH+ GIL+AKDLL  +R 
Sbjct: 62  VREVMVPRPQMEVVDVGDTLDDVIDRVNTTAHSRFPVINGDRDHVVGILLAKDLLR-VRR 120

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           DA  F++ + +R AV +PE KR+D +L+EFR  R HMAIVIDE+ G++GL+TIED+LE I
Sbjct: 121 DA-PFNLREWVRPAVFIPEFKRLDVLLREFRVSRNHMAIVIDEYAGIAGLITIEDVLEQI 179

Query: 189 VGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           VGEIEDEYD +E D + +      + V+A A++ DFN A GTHFSDE+ +T+GGLV+   
Sbjct: 180 VGEIEDEYDFDEADENIQLDQNGLYRVKAHAAVADFNAALGTHFSDEKCNTVGGLVLHHL 239

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           G +P   ETI IDG +F+V  ADSRRI  + V  P ++  P+
Sbjct: 240 GRVPQFNETIVIDGTRFQVLRADSRRIYTLIVTRPPEADSPE 281


>UniRef50_A5EY48 Transporter associated domain protein n=2 Tax=Cardiobacteriaceae
           RepID=A5EY48_DICNV
          Length = 288

 Score =  244 bits (623), Expect = 2e-63,   Method: Compositional matrix adjust.
 Identities = 132/293 (45%), Positives = 190/293 (64%), Gaps = 6/293 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKN-RDELLALIRDSGQNDLIDEDTRDMLE 59
           M+D+ S S  +   K    +LLL+     +P+N +D    L+ D   N  I++DT  M+E
Sbjct: 1   MNDEFSGSKSSWLKK---LALLLTD--KTQPENPQDAFHLLLDDYRHNQTINDDTATMME 55

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
            ++++    VRD+MIPR QM+ +  + +LD+ L VII+S HSR+PVI E  + I GIL+ 
Sbjct: 56  SLLELNHTHVRDVMIPRGQMVVIHEHWSLDKVLSVIIQSGHSRYPVIDESHEKILGILIT 115

Query: 120 KDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           KDLLP +  D E  +   V+R A VVPESK +D ML++FR+ R HMAIVIDE+G +SGLV
Sbjct: 116 KDLLPILVDDDENPNFMAVIRSATVVPESKPLDAMLRDFRTNRNHMAIVIDEYGNLSGLV 175

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED++E IVGEI+DE+D+  D + R L   ++ V+AL  IE FNE F TH  DE+ DTI
Sbjct: 176 TIEDVIEEIVGEIDDEHDQIPDAEIRTLPDGSYQVKALMMIEHFNEQFQTHLPDEDADTI 235

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           GG ++  FG +P  GE + IDG++  V+ A+ RRI+Q+ V   ++    K +E
Sbjct: 236 GGYLLHYFGRIPINGERLSIDGWEIIVSKANQRRILQLKVVATNEEHTEKAEE 288


>UniRef50_Q0VN63 Metal ion transporter n=15 Tax=Gammaproteobacteria
           RepID=Q0VN63_ALCBS
          Length = 295

 Score =  241 bits (614), Expect = 3e-62,   Method: Compositional matrix adjust.
 Identities = 137/266 (51%), Positives = 185/266 (69%), Gaps = 3/266 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           + Q F   P +R+ELL L+R      +ID DT  ++EG + +AD +VR+IMIPRSQM+++
Sbjct: 18  VGQFFSPTPGDRNELLELMRSMRDTHIIDGDTLGIIEGAICVADMQVREIMIPRSQMVSI 77

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--EAFSMDKVLR 140
           K +      L  II+ AHSRFPV+ +D D + GIL+AKDLLP +   A  E F++   +R
Sbjct: 78  KASSDPRGFLPTIIDCAHSRFPVLGDDPDEVIGILLAKDLLPLILDPARMERFAIKDHIR 137

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
            A+VVPESKR+D +L+EFR  R HMAIV++E+GGV+GLVTIED+LE IVGEIEDE+D E+
Sbjct: 138 SAMVVPESKRLDSLLREFRISRNHMAIVVNEYGGVAGLVTIEDVLEQIVGEIEDEHDIEE 197

Query: 201 DIDF-RQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
           D    + L ++ +TV+AL  I+DFNE F   FS+EE DTIGGLVMQ FG LP R E+I +
Sbjct: 198 DDYLIKDLDKNEYTVKALTPIDDFNEHFHCQFSNEEFDTIGGLVMQKFGRLPGRDESITL 257

Query: 260 DGYQFKVAMADSRRIIQVHVKIPDDS 285
           DG++  V  AD R I  + V  P D+
Sbjct: 258 DGFRVTVLSADGRTIRLLRVTPPGDN 283


>UniRef50_A9M203 Magnesium and cobalt transporter n=27 Tax=Neisseriaceae
           RepID=A9M203_NEIM0
          Length = 274

 Score =  238 bits (606), Expect = 2e-61,   Method: Compositional matrix adjust.
 Identities = 138/266 (51%), Positives = 177/266 (66%), Gaps = 3/266 (1%)

Query: 10  DTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           D    K  FF  L+++L   EP + +++L L+R + + ++ D DT   LE V+D +D  V
Sbjct: 2   DGAQPKTNFFERLIARLAR-EPDSAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEV 60

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           RD MI RS+M  LK N +++     +I++AHSRFPVI EDKD + GIL AKDLL +M  +
Sbjct: 61  RDAMITRSRMNVLKENDSIERITAYVIDTAHSRFPVIGEDKDEVLGILHAKDLLKYM-FN 119

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            E F +  +LR AV VPE K +  +LKEFR QR HMAIVIDE+GG SGLVT EDI+E IV
Sbjct: 120 PEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVIDEYGGTSGLVTFEDIIEQIV 179

Query: 190 GEIEDEYDEEDDID-FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           GEIEDE+DE+D  D    +S   W + A   IED N  FGT +S EE DTIGGLV+Q  G
Sbjct: 180 GEIEDEFDEDDSADNIHAVSSERWRIHAATEIEDINTFFGTEYSSEEADTIGGLVIQELG 239

Query: 249 HLPARGETIDIDGYQFKVAMADSRRI 274
           HLP RGE + I G QF VA AD+RR+
Sbjct: 240 HLPVRGEKVLIGGLQFTVARADNRRL 265


>UniRef50_B2I8U5 CBS domain containing protein n=17 Tax=Xanthomonadaceae
           RepID=B2I8U5_XYLF2
          Length = 323

 Score =  236 bits (602), Expect = 6e-61,   Method: Compositional matrix adjust.
 Identities = 130/284 (45%), Positives = 187/284 (65%), Gaps = 3/284 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSL-LLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLE 59
           MS+D+ H + T S +K    L  LS  F G+P   D+L+ ++R +  + +I  DT  M+E
Sbjct: 31  MSEDDDHRTITESQEKRRSWLERLSAAFSGDPHTLDDLMVILRSAEHHGIIATDTLRMME 90

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
           G + IAD  V D+M+PRSQM++L     L      ++ES HSRFPV  E+KD + GIL+A
Sbjct: 91  GAIAIADLTVGDVMVPRSQMVSLPVESDLQTITKQMVESGHSRFPVHGENKDEVLGILLA 150

Query: 120 KDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           KDLL  + ++    ++ ++LR   ++PESK+++ +LKEFR    HMAIV+DE+GGV+GLV
Sbjct: 151 KDLLRGVSANHTITNVHELLRPVGMIPESKKLNVLLKEFRLSHNHMAIVVDEYGGVAGLV 210

Query: 180 TIEDILELIVGEIEDEYDE-EDDIDFRQL-SRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           TIEDILE IVG+I+DE+DE ED  +   + +   + V AL  IEDFNE F   F D++ D
Sbjct: 211 TIEDILEQIVGDIDDEHDETEDQTNMIAIQADGCYIVDALTPIEDFNERFNAEFPDDDYD 270

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           TIGGLV +A GHLP  G+ + I  + F+VA A++RRI  +HV +
Sbjct: 271 TIGGLVTEAIGHLPETGDELTIGRFAFRVAKANARRIHILHVTV 314


>UniRef50_A1WVF4 CBS domain containing protein n=2 Tax=Ectothiorhodospiraceae
           RepID=A1WVF4_HALHL
          Length = 291

 Score =  235 bits (600), Expect = 1e-60,   Method: Compositional matrix adjust.
 Identities = 120/275 (43%), Positives = 177/275 (64%), Gaps = 1/275 (0%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M D  ++SS+       +   L   +   EP++RDEL+  +R S    L+D D   M+EG
Sbjct: 1   MPDGEANSSNGAGESVSWRDRLRRLVTQVEPRSRDELVDHLRRSQSVGLLDADALSMIEG 60

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V+ +++ + RDIMIPRSQ+ T+ R+    + L  I+ + +SRFPV  E KD + GIL+AK
Sbjct: 61  VLHVSELQARDIMIPRSQVTTVARDTAPHDLLPTIVRTGYSRFPVTGESKDDVIGILLAK 120

Query: 121 DLLP-FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLL  F       F + +VLR  + +PESKR+D +LK+FR  R HM++V+DE+GG++G+V
Sbjct: 121 DLLRLFYEEGHNGFRLREVLRPVLFIPESKRLDALLKQFRESRNHMSVVVDEYGGLAGIV 180

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED++E IVGEI+DE+D ++D         +W V+A+  IE FNEA      ++++DT+
Sbjct: 181 TIEDVIEQIVGEIDDEHDFDEDAPILARDDGSWIVKAVTPIEAFNEALSAGLKEDDLDTV 240

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
           GGLV Q FGH+P RGE I   G++F+V  AD RRI
Sbjct: 241 GGLVAQRFGHVPCRGERIVFAGFEFRVLRADQRRI 275


>UniRef50_B7J5B5 Magnesium and cobalt efflux protein, putative n=2
           Tax=Acidithiobacillus ferrooxidans RepID=B7J5B5_ACIF2
          Length = 291

 Score =  232 bits (591), Expect = 1e-59,   Method: Compositional matrix adjust.
 Identities = 120/289 (41%), Positives = 180/289 (62%), Gaps = 5/289 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S         +G++    +Q   G  +++D LL LIR++G+  +ID +T  M++G
Sbjct: 1   MSEDRSSQE----RPRGWWERF-TQSLRGNVEDQDTLLELIREAGERQIIDAETARMVDG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           +  + +  VRD+MIPR+QM  ++ +  L E +  + E  HSRFPV+  D+D + GIL+AK
Sbjct: 56  IFRMGELTVRDVMIPRAQMEVIELDMPLAEIIARVSEVGHSRFPVVGHDRDDVRGILLAK 115

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL   R D  A  +  +LR A  +PESK +D +L EFR+ R+HMA+V+DE+GGV+GL+T
Sbjct: 116 DLLRGCRGDVPALRLTDLLRPATFIPESKHLDHLLYEFRTGRHHMAVVVDEYGGVAGLIT 175

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IED+LE+IVGEIEDEYD ++D+         + V AL  +E+FN  F TH  D   DT+G
Sbjct: 176 IEDVLEIIVGEIEDEYDIDEDVMIAPREDGDFLVNALIPLEEFNAHFVTHLEDGHADTLG 235

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           G V  A GH+P  GE ++    + +V  AD +R+  + V  P  +P P+
Sbjct: 236 GWVAAALGHVPRTGEVVEEGDLRLEVLRADRKRVQILRVTPPRGAPLPE 284


>UniRef50_C4GJN3 Putative uncharacterized protein n=1 Tax=Kingella oralis ATCC 51147
           RepID=C4GJN3_9NEIS
          Length = 289

 Score =  230 bits (587), Expect = 4e-59,   Method: Compositional matrix adjust.
 Identities = 123/260 (47%), Positives = 167/260 (64%), Gaps = 8/260 (3%)

Query: 22  LLSQLFH------GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           L ++LFH      G P+   + L L+  +   + +D+DT   LE +       VRD M+ 
Sbjct: 12  LFNRLFHRVSGSIGIPETPAQWLDLLHQAQAQNSLDDDTLLRLENLFKFNQLSVRDAMMT 71

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R+QM  +K    +D  +   +++AHSRFPVI EDKDHI GIL AKDLL     + E F +
Sbjct: 72  RAQMDVIKTTDGIDRIIAYAVDTAHSRFPVIEEDKDHIIGILHAKDLLK-CTLNPEQFKL 130

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
           + +LR AV VPESK ++ +LK+F++QR HMAIV+DE+GG+SGLVT ED++E IVG+IEDE
Sbjct: 131 EHILRPAVFVPESKSLNSLLKDFQTQRNHMAIVVDEYGGISGLVTFEDVIEQIVGKIEDE 190

Query: 196 YDEEDDID-FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARG 254
           +DE+D  D    +S   W ++A   I   NE FGT FSDEE DTIGGLV+   GHLP RG
Sbjct: 191 FDEDDSADNIFPVSAERWRIKATTEIAAINEYFGTDFSDEEADTIGGLVIHELGHLPVRG 250

Query: 255 ETIDIDGYQFKVAMADSRRI 274
           E + +    F VA AD+RR+
Sbjct: 251 EKVQLGDLLFNVARADNRRL 270


>UniRef50_Q3JVV5 Magnesium and cobalt efflux protein CorC n=105 Tax=Proteobacteria
           RepID=Q3JVV5_BURP1
          Length = 403

 Score =  228 bits (582), Expect = 2e-58,   Method: Compositional matrix adjust.
 Identities = 124/280 (44%), Positives = 182/280 (65%), Gaps = 7/280 (2%)

Query: 8   SSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           SSD    K+     L + +   EP +R ELL +++D+ + +LID D+  M+EGV  ++D 
Sbjct: 118 SSDKPHEKRSLLERL-TDIISPEPDSRAELLEILQDAHERNLIDADSLSMIEGVFQVSDL 176

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
             RDIM+PR+QM  L      ++ +  ++E AHSR+PV  +++D++ G+L+AKDLL F  
Sbjct: 177 CARDIMVPRAQMDALNIADKPEDFIPFVLEKAHSRYPVYEDNRDNVIGVLLAKDLLRFYA 236

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
              E F +  +LR AV +PESKR++ +L +FR  R H+AIV+DE+GGV+GL+TIED+LE 
Sbjct: 237 E--EEFDVRGMLRPAVFIPESKRLNVLLHDFRVNRNHLAIVVDEYGGVAGLITIEDVLEQ 294

Query: 188 IVGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
           IVG+IEDEYD +E+  +        + VRAL  IE FNE FGT FSD+EVDTIGGL+   
Sbjct: 295 IVGDIEDEYDFDEEAGNIIAAPDGRYRVRALTEIEQFNETFGTDFSDDEVDTIGGLITHH 354

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
           FG +P RGE + +    F++   D+R   Q+HV +   +P
Sbjct: 355 FGRVPHRGEKVRLGELLFEIQRGDAR---QIHVLLVRRAP 391


>UniRef50_A4NW42 N-acetyl-anhydromuranmyl-L-alanine amidase n=1 Tax=Haemophilus
           influenzae 22.4-21 RepID=A4NW42_HAEIN
          Length = 195

 Score =  228 bits (580), Expect = 2e-58,   Method: Compositional matrix adjust.
 Identities = 121/178 (67%), Positives = 145/178 (81%)

Query: 107 SEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMA 166
           ++D+D+I GIL AKDLL F+R DAEAF +  +LR  V+VPESKRVDRMLK+FRS+R+HMA
Sbjct: 5   ADDRDNIVGILHAKDLLKFLREDAEAFDLSSLLRPVVIVPESKRVDRMLKDFRSERFHMA 64

Query: 167 IVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEA 226
           IV+DEFG VSGLVTIEDILE IVG+IEDE+DEE+  D RQLSRHT+ VRAL  I+DFN  
Sbjct: 65  IVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIADIRQLSRHTYAVRALTDIDDFNGQ 124

Query: 227 FGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           F T F DEEVDTIGGL+MQ FG+LP RGE I +   QFKV  ADSRR+IQ+ V +PD+
Sbjct: 125 FNTDFDDEEVDTIGGLIMQTFGYLPKRGEEIILKNLQFKVTSADSRRLIQLRVTVPDE 182


>UniRef50_B6BWN1 Putative uncharacterized protein n=1 Tax=beta proteobacterium KB13
           RepID=B6BWN1_9PROT
          Length = 280

 Score =  226 bits (576), Expect = 7e-58,   Method: Compositional matrix adjust.
 Identities = 115/247 (46%), Positives = 172/247 (69%), Gaps = 5/247 (2%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           +PK ++ELL L++ S Q +LID D+  MLEGV+ I+D + RD+MIPRSQ+  +  N ++D
Sbjct: 19  QPKTKEELLILLQKSYQANLIDSDSLMMLEGVLGISDMQARDVMIPRSQVSFININDSVD 78

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA-FSMDKVLRQAVVVPES 148
             +D  + +AHSRFPVI ED +++ GIL+AKDL   +R + E    +  +LR  V +PES
Sbjct: 79  VIIDTALHTAHSRFPVIDEDSNNVIGILLAKDL---VRLNKEKDLDLRDILRPPVYIPES 135

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD-EEDDIDFRQL 207
           K+++ +LKEFRS R H+AIV+DE+ G++G++TIED+LE IVGEIEDE+D +E++ +  Q 
Sbjct: 136 KKLNVLLKEFRSNRNHIAIVVDEYAGIAGILTIEDVLEQIVGEIEDEFDYDENEDNIIQE 195

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
              T+ ++A   +E+FNE F T++   E  T+GGLV+   GHLP + E I  DG+  +V 
Sbjct: 196 ETATFRIKASTELEEFNEFFKTNYPINEYQTVGGLVISKLGHLPKKNEPIHFDGFDIEVL 255

Query: 268 MADSRRI 274
             DSRR+
Sbjct: 256 RRDSRRL 262


>UniRef50_A6VZE4 CBS domain containing protein n=9 Tax=Gammaproteobacteria
           RepID=A6VZE4_MARMS
          Length = 288

 Score =  218 bits (556), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 121/285 (42%), Positives = 180/285 (63%), Gaps = 6/285 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MSDD S  S+    +K +F  L +Q F+ EP++R +++ L+  + ++D+ID D   ++EG
Sbjct: 1   MSDDRSSLSN--DQQKSWFERL-TQAFNDEPRSRGDIVKLLEAAVKSDVIDRDAFTIVEG 57

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI--LM 118
            +++++ + RDIMIP SQM+ +K        +  II+S+HSRFPV+ ED D I G+    
Sbjct: 58  ALEVSEVQARDIMIPPSQMVVIKSEDDPKTSIRKIIDSSHSRFPVVGEDSDEILGVLLAK 117

Query: 119 AKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
               L F   D     +   LR A  +PESKR++ +L +FR++RYHMA+V+DE+G VSGL
Sbjct: 118 DLLPLLFKEGDITIEDILARLRPANFIPESKRLNVLLNDFRTKRYHMALVLDEYGSVSGL 177

Query: 179 VTIEDILELIVGEIEDEYDEEDDIDFRQLSRH-TWTVRALASIEDFNEAFGTHFSDEEVD 237
           VTIED+LE IVGEIEDE D+ DD   +  +    + V AL  +EDFNE F    ++EE D
Sbjct: 178 VTIEDVLEQIVGEIEDETDKLDDEGIQVTTEPGVYLVPALCPVEDFNEFFKVELNEEEFD 237

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           TIGG+++Q FGH+P R E +  + + F+V  +D RRI  + V  P
Sbjct: 238 TIGGILVQQFGHVPLRDEELFFNNFHFRVVKSDGRRIKTIQVTKP 282


>UniRef50_A5CVQ3 Magnesium/cobalt efflux protein n=5 Tax=Bacteria RepID=A5CVQ3_VESOH
          Length = 282

 Score =  218 bits (554), Expect = 3e-55,   Method: Compositional matrix adjust.
 Identities = 109/270 (40%), Positives = 178/270 (65%), Gaps = 6/270 (2%)

Query: 8   SSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           + +  S K  F   L  +  H   ++ DELL +++++ +N +ID ++R ++EG M +   
Sbjct: 2   NKEQFSLKSFFLQRLKKRYLHIPLRSSDELLRMLKEAEENYIIDSNSRSIIEGTMQLEKL 61

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
            VRD+M+P+S+M+ ++   T  E LD++I+S+HSRFP+I+ DK+ I+G+++AKDLL F+ 
Sbjct: 62  EVRDVMVPKSKMVMIEHQSTTKELLDIMIKSSHSRFPIINSDKNKIQGVILAKDLLGFLV 121

Query: 128 SDAE-AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
                 F+  + LR ++ VPESK +  +L++F+ ++ HMAIV+DE+G ++GLVT+ED+LE
Sbjct: 122 EKQNFEFNYKQYLRDSLFVPESKTLGALLRDFQQKKSHMAIVMDEYGEIAGLVTLEDVLE 181

Query: 187 LIVGEIEDEYDEEDD--IDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVM 244
            IVGEIEDE+D E+D  IDF       + ++A   IE+F+E F      E +DT+ GLV+
Sbjct: 182 QIVGEIEDEHDLEEDNIIDF---GEGRFLLKANTPIEEFDEFFKVKLQVENLDTVAGLVI 238

Query: 245 QAFGHLPARGETIDIDGYQFKVAMADSRRI 274
           + F  LP + + I + G+ FK+   DSRRI
Sbjct: 239 KGFTRLPEQMDEISLQGFNFKILKTDSRRI 268


>UniRef50_C3X3R1 Magnesium and cobalt efflux protein n=1 Tax=Oxalobacter formigenes
           HOxBLS RepID=C3X3R1_OXAFO
          Length = 324

 Score =  209 bits (532), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 122/290 (42%), Positives = 174/290 (60%), Gaps = 11/290 (3%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M +   HS +T    + F   L S     EP  R ELL ++ D+ +  LID +   M+EG
Sbjct: 32  MPEHPEHSQNTNKPARTFLDRLAS-FISSEPDTRTELLDILHDAHERKLIDSECLSMIEG 90

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V  + D  VRD+MIPRSQM  +   + + E +  ++E+ HSR+P I  D + I GI+ AK
Sbjct: 91  VFRLFDSAVRDVMIPRSQMYVIDITRPVSEWIGEVMENGHSRYPAIEGDAEKIVGIVHAK 150

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL +     E FS+ ++L  AV +PESKR++ +L++FR+   HMAIV+DEFG +SGLVT
Sbjct: 151 DLLHYRE---EGFSVREILHPAVFIPESKRLNVLLRDFRNTHNHMAIVVDEFGNISGLVT 207

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHT----WTVRALASIEDFNEAFGTHFSDEEV 236
           IED+LE IVG+IEDE+D+++D     L        W + AL  ++DFN   GT  +D  V
Sbjct: 208 IEDVLEQIVGDIEDEFDDDEDDKIVALKAGATGPRWRIPALTEMDDFNRTLGTKLADSRV 267

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
           DTIGG V    G +P +G+  DIDG  F+V  AD+R   Q+H  + +  P
Sbjct: 268 DTIGGYVANHLGRVPHKGDAFDIDGLHFEVVRADAR---QLHTLVVEKKP 314


>UniRef50_Q1Q8E9 CBS domain n=21 Tax=Moraxellaceae RepID=Q1Q8E9_PSYCK
          Length = 299

 Score =  201 bits (511), Expect = 2e-50,   Method: Compositional matrix adjust.
 Identities = 113/267 (42%), Positives = 169/267 (63%), Gaps = 17/267 (6%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           L +     P+ RDEL+ L++DS Q   ++ DT DMLEGV+D+   +VR+IM PR Q++ L
Sbjct: 16  LKRWLSTAPETRDELIRLVQDSRQ--FLEPDTVDMLEGVLDLPATQVREIMTPRPQVVGL 73

Query: 83  KRNQTLDECLDVIIESAHSRFPVI-SEDKDHIEGILMAKDLLPFM----RSDAEAFSMDK 137
             + +L E +D+I+E+ HSR+PV  S+D D + GIL+AKDL+P +    R + E  S  +
Sbjct: 74  HESASLAEVMDIILETTHSRYPVFDSQDDDAVIGILLAKDLIPLLVHMVRDEEEKISSKR 133

Query: 138 V---LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +   +RQ + + ES R D +L+  +  + HMAIV+DEFG   G+VT+ED+LE IVG+I D
Sbjct: 134 LRDLVRQPLYISESARSDTLLRSLQRTQVHMAIVVDEFGNFGGVVTMEDLLEEIVGDIVD 193

Query: 195 EYDE-EDDIDFRQL-----SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           E+D+ ++D D   +       +TW V+A   IED N+  G HF D +VDT+GGLVMQ  G
Sbjct: 194 EHDDFDEDSDINNIVADPEKPNTWRVQASTVIEDCNDELGCHFDDTDVDTMGGLVMQTLG 253

Query: 249 HLP-ARGETIDIDGYQFKVAMADSRRI 274
           H+    GE++ ID +Q  +   + R I
Sbjct: 254 HVGDLEGESVVIDDWQITITDVEGRFI 280


>UniRef50_Q31IF1 Transporter associated domain/CBS domain protein n=1
           Tax=Thiomicrospira crunogena XCL-2 RepID=Q31IF1_THICR
          Length = 320

 Score =  199 bits (505), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 110/254 (43%), Positives = 179/254 (70%), Gaps = 3/254 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           LS+LF  EP++R++L + ++++   DLID+D   M++GV+D+++ RVRD+MIP+ QM  +
Sbjct: 14  LSKLFSDEPESREDLDSFLQEAQAQDLIDKDALLMIQGVLDVSEARVRDVMIPKVQMSCV 73

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD--AEAFSMDKVLR 140
                LD  L+ ++++AHSR+PV+S D D + GIL+AKD+L  +      +   ++++ R
Sbjct: 74  DEADELDVILETMLDAAHSRYPVLSADTDEVIGILLAKDVLRAVVKHQLTDKTQLEELYR 133

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
             V+V ESKR++ +L+EF++ R HMA+V+DE+G V+GLVTIED+LE IVG+IEDE+DE+D
Sbjct: 134 TPVLVSESKRLNVLLREFKNSRNHMALVVDEYGEVAGLVTIEDVLEQIVGDIEDEHDEDD 193

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
           D   + +S   + V+A+ S+++FN+ F T F DE ++TIGG+V +  G +P   E  +I+
Sbjct: 194 DNIQKHIS-GAYAVKAITSLDEFNQFFNTTFEDELLETIGGVVAKRLGKIPEEDEVFEIE 252

Query: 261 GYQFKVAMADSRRI 274
           G +  V  AD RR+
Sbjct: 253 GLRLTVLKADERRV 266


>UniRef50_C6NUU3 Magnesium and cobalt efflux protein CorC n=1 Tax=Acidithiobacillus
           caldus ATCC 51756 RepID=C6NUU3_9GAMM
          Length = 292

 Score =  199 bits (505), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 113/282 (40%), Positives = 177/282 (62%), Gaps = 5/282 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S    + S    F     +Q   G  +++D LL LIR++G+  +ID +   M++G
Sbjct: 1   MSEDRSSPERSRSWWARF-----TQSLRGNVEDQDTLLDLIREAGERQVIDAEAARMVDG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           +  + +  VRD+MIPR+QM  ++ +  + E +  ++E  HSRFPV+  D+D + GIL+AK
Sbjct: 56  IFRMGELSVRDVMIPRAQMEVIELDLPIPEIIARVVEVGHSRFPVVGNDRDDVRGILLAK 115

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL       E   + ++LR A  +PESK +D +L EFR+ R+HMA+V+DE+GGV+GL+T
Sbjct: 116 DLLRACGQGQEPPRLTELLRPATFIPESKHLDHLLYEFRTGRHHMALVVDEYGGVAGLIT 175

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IED+LE+IVGEIEDEYD E+D+         + V A+ ++ +FN  F T+  DE  DT+G
Sbjct: 176 IEDVLEIIVGEIEDEYDIEEDVMVVPREDGDFLVNAVITLPEFNTQFHTNLDDEYADTLG 235

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           G +    GH+P  GE + +DG + +V  AD +R+  + + +P
Sbjct: 236 GWLSNRLGHVPRVGEVVMVDGLRLEVLRADRKRVQILRLSLP 277


>UniRef50_A9BXY0 CBS domain containing protein n=17 Tax=cellular organisms
           RepID=A9BXY0_DELAS
          Length = 307

 Score =  194 bits (493), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 113/271 (41%), Positives = 164/271 (60%), Gaps = 8/271 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           +SD +   S    +K+ F   + ++  H  P + DEL+  + D+  N +I  ++R MLE 
Sbjct: 15  VSDPHPARSSEKESKRSFLQKV-AEFIHPAPDSPDELIETLADAEDNQVIGPESRVMLER 73

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V+ +AD    D+M+   +M  +  +   DE L  +I +AHSRFPV   ++++I GIL+AK
Sbjct: 74  VIRMADMTAGDVMVAAPRMDLVNIDAPFDELLHQVITTAHSRFPVYQGERENIIGILLAK 133

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL   RS     ++  +LR A  VPESK ++ +L+EFR  R H+A+VIDEFG V+GLVT
Sbjct: 134 DLLKLQRS--PDLNIRALLRPAAFVPESKGLNDLLREFRGNRNHLAVVIDEFGRVAGLVT 191

Query: 181 IEDILELIVGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF----SDEE 235
           IED+LE IVGEIEDE+D  ED+ D   L+ +++ V    +IE  NE F         D+E
Sbjct: 192 IEDVLEEIVGEIEDEFDIPEDEGDIFALADNSYRVAGDTTIEHVNETFEVALHARDPDDE 251

Query: 236 VDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
            DTIGGL+    GH+P RGE I + G +F V
Sbjct: 252 FDTIGGLIAHEMGHVPKRGEQIHLAGLEFTV 282


>UniRef50_Q14IK8 Metal ion transporter protein n=17 Tax=Francisella
           RepID=Q14IK8_FRAT1
          Length = 286

 Score =  188 bits (478), Expect = 1e-46,   Method: Compositional matrix adjust.
 Identities = 102/272 (37%), Positives = 170/272 (62%), Gaps = 13/272 (4%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           F   L S +F+   K+ + L+  I  +  N++ID+ +++ML G M I+   V DIMI  +
Sbjct: 13  FIKRLTSSIFN--IKSEEALIDAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIMISHT 70

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM---------RS 128
           +++ +  + ++ E L   I S+H+R PV  E+K  I GIL +KDLL  +           
Sbjct: 71  KIVAVDMSMSIREILKKTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIESADDE 130

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           + +A  +  +LR A+ +PE+K+++ MLK+F++ + H+AIV+DE+G +SGL+TIED+LE I
Sbjct: 131 ELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNHIAIVVDEYGAISGLITIEDVLEEI 190

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAF 247
           VG+IEDE+D     +  +++   + + A  +IEDFNE F T   D  + DTI G+++Q  
Sbjct: 191 VGDIEDEFDITSQ-NIVKMADDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMIIQTL 249

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
             LP +G++I +DG +F V  AD+R+II++ V
Sbjct: 250 ECLPQKGDSIVVDGLKFTVQEADNRKIIKILV 281


>UniRef50_Q3A2F6 Uncharacterized CBS domain-containing protein n=2
           Tax=Desulfuromonadales RepID=Q3A2F6_PELCD
          Length = 417

 Score =  188 bits (478), Expect = 2e-46,   Method: Compositional matrix adjust.
 Identities = 100/273 (36%), Positives = 169/273 (61%), Gaps = 5/273 (1%)

Query: 19  FSLLLSQLFHGEPK---NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           FS LL+     EP+   + +E+  LI    Q+ ++ +D R ML+G+ D++   VRD+MIP
Sbjct: 147 FSRLLTLFVKSEPQPVISEEEIRTLITVGEQSGVVGKDKRKMLDGIFDLSQICVRDVMIP 206

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R+++  L  + +  E L ++ +S+HSRFP+     D++ GI+ +KD+L ++   +E FS+
Sbjct: 207 RTEIAALDVSFSFAEVLRLVQQSSHSRFPIYEGSLDNVIGIIHSKDILRYVHI-SEEFSL 265

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
           +K+ R+   VPESKR++ +L  F+ ++ HMA+V+DE+GGV GLVT+ED++E IVGEI DE
Sbjct: 266 EKLARKPYFVPESKRINTLLPAFQRRQVHMAVVVDEYGGVEGLVTLEDVVEEIVGEIRDE 325

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
           YD ++D+   +L    + + A  S+   N+ FG   S+E   T+ G ++   G +P  G+
Sbjct: 326 YDIDEDM-VCELRPGRYLLDASISLRAVNQRFGLELSEEHASTLAGFLLGVLGSIPRVGD 384

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           + ++D   F V      RI ++ + +P DSP P
Sbjct: 385 SCEVDKSHFIVRKVIHHRIEEIELLLPPDSPDP 417


>UniRef50_C1SMP1 CBS domain-containing protein n=1 Tax=Denitrovibrio acetiphilus DSM
           12809 RepID=C1SMP1_9BACT
          Length = 434

 Score =  185 bits (470), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 108/258 (41%), Positives = 154/258 (59%), Gaps = 5/258 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           DEL   I +S +  +I+     ML+ + DI++  V+++M+PR+ M+ +     ++  +D 
Sbjct: 169 DELEFYICESEKEGIIENGKSRMLQNIFDISEIYVKEVMVPRTDMVAIDIEDPVESYIDK 228

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
           I  S  SR PV  E  D I GIL  KDLL F+  D+  F + KVLR+   +PE+K++D M
Sbjct: 229 IHASEFSRIPVYEETIDKIIGILYVKDLLRFVNEDSTQFDLRKVLRKPYFIPETKKIDSM 288

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
           L EF+  R HMAIVIDE+GGV GLVT+EDILE IVGEI DEYD E+  +  ++S +T+ V
Sbjct: 289 LSEFQRNRNHMAIVIDEYGGVDGLVTLEDILEEIVGEIWDEYDTEEQ-EVTEISENTFIV 347

Query: 215 RALASIEDFNEAFG---THFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
                I+DF E FG   TH  D E +T+GGLV      +P  GE    + YQFK+     
Sbjct: 348 DVRMDIDDFCEKFGLEKTHEMD-EYETVGGLVFDIAEKIPEVGEQYVYENYQFKILNKHE 406

Query: 272 RRIIQVHVKIPDDSPQPK 289
           RR+ +V ++  +  P  K
Sbjct: 407 RRLDKVELRRIEKEPDEK 424


>UniRef50_C8X404 CBS domain containing protein n=2 Tax=Desulfovibrionales
           RepID=C8X404_DESRD
          Length = 285

 Score =  185 bits (470), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 103/271 (38%), Positives = 162/271 (59%), Gaps = 10/271 (3%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLAL-IRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           + +G    L+ + F G+ +N  E + L  R  G+ +  +     ML  V+ +  ++VR+I
Sbjct: 4   SPEGKLWTLVRKFFSGKTENPIEDVILEARTDGELEAFE---ASMLINVLRMGRKQVREI 60

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           MIPR+ +  +++N ++ +  ++IIE  HSR PV  E+KDHI G++ AKDLLP++ +  E 
Sbjct: 61  MIPRTDIQCVEQNASIQDVAELIIEHGHSRIPVYRENKDHIIGVVHAKDLLPYLLNHCET 120

Query: 133 FS--MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
               +  ++R    +PE+K V  M+ EF++Q+ HMAI +DE+GG SGLVT ED+LE IVG
Sbjct: 121 PPDPLSAIMRPPFFIPETKNVKNMIAEFQAQKVHMAIALDEYGGTSGLVTFEDVLEEIVG 180

Query: 191 EIEDEYD--EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           EIEDEYD    +DI   +  RH   V    S+ D  E  G   + ++V+TIGG V +  G
Sbjct: 181 EIEDEYDLPRPEDIQVMEDGRH--LVAGRTSLNDLEEETGVSLTSDQVETIGGFVTELAG 238

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
            +P  GE  D  G+ F++  ADS+++  V +
Sbjct: 239 RVPMTGEEFDYLGHNFRIEEADSKQVYAVSI 269


>UniRef50_A7NHB2 CBS domain containing protein n=1 Tax=Roseiflexus castenholzii DSM
           13941 RepID=A7NHB2_ROSCS
          Length = 435

 Score =  182 bits (462), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 97/233 (41%), Positives = 148/233 (63%), Gaps = 4/233 (1%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
           R+M+EG+    D  VR++MIPR  ++ L+   ++DE L++II + HSR PV  E  DHI 
Sbjct: 189 REMIEGIFSFGDTTVREVMIPRVDIVALEETASIDEALNIIITTGHSRIPVYRETIDHIV 248

Query: 115 GILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGG 174
           GIL AKDLL ++RS     S+  +LR A  VP++ +VD +LK+ ++++ H+AIV+DE+GG
Sbjct: 249 GILYAKDLLLWLRSGQRDASIGALLRTAHFVPDTMKVDALLKDLQARKIHLAIVVDEYGG 308

Query: 175 VSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE 234
            +GL+TIED++E IVGEI+DEYD  D+   R L+     V A   I+D N+  G   + E
Sbjct: 309 TAGLITIEDVIEEIVGEIQDEYD-VDEQPIRVLAPGDMEVDARVPIDDINDLTGLRLASE 367

Query: 235 EVDTIGGLVMQAFGHLPARGETIDI-DGYQFKVAMADSRRI--IQVHVKIPDD 284
           E D IGG+V +  G +P  G+T+ I DG    V   D  R+  +++  ++P +
Sbjct: 368 ESDRIGGMVFERLGRVPKVGDTVQIADGVTVVVLSMDGLRLRKLRLQYRLPQE 420


>UniRef50_D2DIN9 CBS domain-containing protein n=1 Tax=uncultured Chloroflexi
           bacterium 1i19 RepID=D2DIN9_9CHLR
          Length = 455

 Score =  182 bits (462), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 102/289 (35%), Positives = 166/289 (57%), Gaps = 15/289 (5%)

Query: 6   SHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLA------------LIRDSGQNDLIDED 53
           + S D ++      S+LL +L      + DE+ A            LI       +I+ED
Sbjct: 128 ARSVDLVAVVLAPLSILLRRLASSARGDEDEVTAESVFLSEDGLRFLIHVGEGEGVIEED 187

Query: 54  TRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHI 113
            + M+ G+ +  +  VR+IM+PR  ++ ++    L + LD+II + HSR PV  +  DH+
Sbjct: 188 EKQMIAGIFEFGETTVREIMVPRLDIVAVEVTAPLSQALDLIIGNGHSRIPVYEDSIDHL 247

Query: 114 EGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFG 173
            G+L AKDLL  +R  ++  S+ ++LR+A  VP+SK++D + +E ++ R HMA+ +DE+G
Sbjct: 248 LGVLYAKDLLLCLRDGSQDISVRQLLRKAYFVPQSKKLDELFEEMQAHRIHMALAVDEYG 307

Query: 174 GVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD 233
           G +GLVTIED+LE IVGEI+DEYD E+    ++L+   +   A   I++ +       S 
Sbjct: 308 GTAGLVTIEDLLEEIVGEIQDEYDSEEP-QLKKLAPEIYIFNARYDIDEVSRLIDVDLSA 366

Query: 234 --EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
             E +DT+GG +    G +P +GE+I    ++F V   DSRRI +V V+
Sbjct: 367 GRENIDTLGGFIYSQLGRVPEQGESIQFKDWRFTVLSVDSRRIEEVRVE 415


>UniRef50_A9I003 Magnesium and cobalt efflux protein n=5 Tax=Bordetella
           RepID=A9I003_BORPD
          Length = 298

 Score =  182 bits (462), Expect = 1e-44,   Method: Compositional matrix adjust.
 Identities = 115/294 (39%), Positives = 182/294 (61%), Gaps = 5/294 (1%)

Query: 1   MSDD-NSHSSDTISNKKGFFSLL--LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDM 57
           MSD   ++ ++T   +K   SLL  +  L   EP++R+ + A++  +    L+D ++  M
Sbjct: 1   MSDPYPANDANTNRARKPTKSLLDRMLALVRREPEDREGIKAVLDAAHDRALLDVESYGM 60

Query: 58  LEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGIL 117
           ++G + ++++ V DIM+PRS+M  L  +Q L + L  IIE+AHSRFPV  +D+D+I GIL
Sbjct: 61  IKGALAMSERSVADIMVPRSRMDLLDVSQPLPQQLAFIIETAHSRFPVYEDDRDNIIGIL 120

Query: 118 MAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSG 177
           +AKDLL  M        +  ++R AV +PE+KR++ +L++FR+   H+AIVIDE GG+SG
Sbjct: 121 LAKDLLRGMLE--PGIELRSLIRPAVFIPEAKRLNVLLRDFRASHNHLAIVIDEHGGISG 178

Query: 178 LVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           LVT+ED+LE IVG+IEDE+D++D+        + W + A   I  FNEAF T   D+E D
Sbjct: 179 LVTMEDVLEQIVGDIEDEFDDDDEQSIFPEGDNQWRLMASTEISHFNEAFSTDLPDDEYD 238

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           ++GG +    G +P RG++        +V  AD+RR + +  K   D+ +P  D
Sbjct: 239 SVGGWLGGQLGRIPRRGDSAAHGDLLIEVIRADARRALWLRAKRTSDAAKPGSD 292


>UniRef50_D1CDD2 CBS domain containing protein n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CDD2_THET1
          Length = 434

 Score =  180 bits (457), Expect = 5e-44,   Method: Compositional matrix adjust.
 Identities = 100/254 (39%), Positives = 152/254 (59%), Gaps = 6/254 (2%)

Query: 31  PKN----RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQ 86
           P+N     D+L  L+    +  +I+++ RDM+ G++   D    ++M+PR  ++ +  N 
Sbjct: 166 PRNPFITEDDLRMLVNAGEEEGVIEQEERDMIAGILRFGDIAAHEVMVPRPDIVAVDVNT 225

Query: 87  TLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVP 146
            L   LD+ +E  HSR PV  E  D++ GI+  KDL   + S +   S+  + R AV +P
Sbjct: 226 DLRTALDLALEKGHSRLPVYEESLDNVVGIVYLKDLARAIVSSSNV-SLRDLARPAVFIP 284

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           ESKR+  +L+EF+S + HMAIV+DE+GG +GL+TIEDILE IVGEI+DEYD E   D  +
Sbjct: 285 ESKRLGELLQEFQSSKVHMAIVVDEYGGTAGLITIEDILEEIVGEIQDEYDVELP-DIEK 343

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
           +S   W +RA   ++D NE  G H   EE DT+GG +      LP  G+ ++++G   KV
Sbjct: 344 ISEDEWIIRAKIDLDDVNELLGIHLPAEEYDTLGGFITAQLERLPVPGDEVEVEGVLMKV 403

Query: 267 AMADSRRIIQVHVK 280
              + RR+ +V VK
Sbjct: 404 LDIEKRRVGRVLVK 417


>UniRef50_D0MD79 CBS domain containing protein n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MD79_RHOM4
          Length = 421

 Score =  179 bits (454), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 99/262 (37%), Positives = 157/262 (59%), Gaps = 9/262 (3%)

Query: 31  PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDE 90
           P + DEL AL  +  Q+ ++ ED R++L  +++  +  VR+IM+ R  ++ +    T  E
Sbjct: 155 PLSPDELKAL--EVAQDGMLGEDERELLAAILEFGETTVREIMVSRLDIVAIPETATFGE 212

Query: 91  CLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RSDA-EAFSMDKVLRQAVVVPES 148
            L  I  S HSR P+ +E  D+I GI+ AKDLLP++ R++  +  +   + R A+ VP S
Sbjct: 213 VLACIRTSGHSRLPLYAEHLDNILGIVYAKDLLPYLGRAELDQPLNWRDIARPAMFVPLS 272

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           KR+D +L++F+ ++ HMAIV+DE+GG +GLVT+ED+LE IVG+I DE+DE + + + QL 
Sbjct: 273 KRLDDLLRDFQRRKTHMAIVVDEYGGTAGLVTLEDVLEEIVGDIRDEHDETEPVLYEQLD 332

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVD--TIGGLVMQAFGHLPARGETIDIDGYQFKV 266
            HT+ V A  +++D  E  G     E  D  T+GGL+    G +P  G+ +       +V
Sbjct: 333 EHTYRVDARMNLDDLAELLGIELDTESFDFETLGGLIFHLLGVIPEPGDEVQYGPLHLRV 392

Query: 267 AMADSRRIIQVHVKIPDDSPQP 288
              D+ RI QV V++    P P
Sbjct: 393 ETVDNHRIGQVLVRV---EPTP 411


>UniRef50_D1Y8K6 CBS/transporter domain protein n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y8K6_9BACT
          Length = 421

 Score =  177 bits (449), Expect = 3e-43,   Method: Compositional matrix adjust.
 Identities = 90/248 (36%), Positives = 155/248 (62%), Gaps = 1/248 (0%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
            ++E+  +++    +  I+E  R M++GV+   + RV +IMIPR++M  ++  +T+D+ L
Sbjct: 167 TKEEIGQVVKIGEASGAIEESERQMIDGVISFDEIRVSEIMIPRTRMHMIESERTVDDAL 226

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
             I +   SR PV ++  D IEGI++ KDLL  +    +   + K +R  + VPE+  V 
Sbjct: 227 QFIEKMGDSRVPVFTDTPDRIEGIVLVKDLLTALMKGQKNAPVTKFMRTPLFVPETMYVP 286

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
           ++ +  ++ R HMA+V+DE+GG +GL+T+ED+LE IVGEI+DEYD+E+      LS  T+
Sbjct: 287 KLFRIMQNVRMHMAVVVDEYGGTAGLITLEDLLEEIVGEIQDEYDKEEQ-TVTPLSDGTY 345

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
             +A   +E+ N+   +HF  ++VDT+GG ++  FG+ P  G+T+  DG+ F++A  D  
Sbjct: 346 RAKASIPLEELNDVLNSHFVCDDVDTLGGFLLDRFGNFPHEGDTLASDGWLFEIASMDGH 405

Query: 273 RIIQVHVK 280
           RI  V ++
Sbjct: 406 RINDVMIR 413


>UniRef50_Q310P2 CBS n=6 Tax=Desulfovibrionaceae RepID=Q310P2_DESDG
          Length = 298

 Score =  175 bits (444), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 93/259 (35%), Positives = 156/259 (60%), Gaps = 3/259 (1%)

Query: 22  LLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT 81
           L S+ F    KN D +   I ++  +  +D +   ML  ++ + + +V +IM PR+ +  
Sbjct: 38  LFSRFFSA--KNGDSVEQAIIEAQDDGELDSEESTMLLSILRLDEMQVYEIMTPRTDIDC 95

Query: 82  LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE-AFSMDKVLR 140
                +L + +D+I+ S HSR PV  +++D+I G++ AKDLL  +    + +  + + +R
Sbjct: 96  ADDQSSLGDIIDLIVSSGHSRIPVYRDNRDNIIGVVYAKDLLSVLTDTGQRSAPVTETMR 155

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
           Q + VPE+K+V  +L+EFR+++ H+AI +DE+GG SGLVTIED+LE+IVG+IEDE+D   
Sbjct: 156 QPIFVPETKKVSELLQEFRTRKNHLAIALDEYGGTSGLVTIEDVLEVIVGDIEDEHDAPR 215

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
             D R L   T  V   A +ED +E  G     ++V+TIGG + +  GH+P  GE+  + 
Sbjct: 216 QEDIRALDDGTLEVSGRAFLEDLSERLGVLLESDQVETIGGYLSEIAGHVPQAGESFTVG 275

Query: 261 GYQFKVAMADSRRIIQVHV 279
            + + V  AD+++I  + V
Sbjct: 276 AHSYTVMEADAKQIKTIRV 294


>UniRef50_D0RQJ3 CBS domain containing protein n=1 Tax=alpha proteobacterium HIMB114
           RepID=D0RQJ3_9RICK
          Length = 281

 Score =  175 bits (444), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 82/236 (34%), Positives = 145/236 (61%), Gaps = 1/236 (0%)

Query: 45  GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFP 104
            QN  +    + +L  ++ I   +  D+MIPR+ ++ + +N +    +D I + +HSR P
Sbjct: 42  SQNIDLSSKEKSILSNILSINKLKADDVMIPRASIVAISQNSSFKNVIDTIDKESHSRMP 101

Query: 105 VISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYH 164
           V  +D D + G++  KD++ F  S+   F++ K++R+ + VP +  V  +L + ++ + H
Sbjct: 102 VFRKDLDDVLGMIHIKDIIKFAGSNYNDFNIKKIMREVLFVPPTMPVMNLLLKMQATKLH 161

Query: 165 MAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN 224
           MA+VIDE GG  GL+TIED++E IVGEIEDE+D++DD +F+++  +T+  +A  +++DFN
Sbjct: 162 MALVIDEHGGTDGLITIEDVIEEIVGEIEDEHDKDDDFNFKKIDSNTFEAKADMTLDDFN 221

Query: 225 EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDG-YQFKVAMADSRRIIQVHV 279
                   +E VDT+GG +      +P  GE I +D  YQF++  AD R+I ++ +
Sbjct: 222 HESNLSIVEENVDTLGGYIFSKINRVPYAGEVIKVDNTYQFEIIEADPRKIKKIRI 277


>UniRef50_C7LZP2 CBS domain containing protein n=1 Tax=Acidimicrobium ferrooxidans
           DSM 10331 RepID=C7LZP2_ACIFD
          Length = 420

 Score =  175 bits (443), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 91/261 (34%), Positives = 148/261 (56%), Gaps = 1/261 (0%)

Query: 20  SLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQM 79
           +LL      G   +  ELLA+   + Q D+I+ D R+++  V+   D   R++M+PR  +
Sbjct: 152 ALLTPWRAPGATVSEAELLAMADAAEQGDVIETDERELIHSVISFGDTIAREVMVPRPDV 211

Query: 80  ITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVL 139
           + +    T+   ++V+IE   SR PV     D++ GI++AKDLL    +      + + +
Sbjct: 212 VAVPAETTVAGAIEVVIEVGRSRLPVYESSLDNVLGIVLAKDLLALEHTGLRDVPVGQHM 271

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
           R    VPE+K V  +LKE R  ++H+A+V+DE+G  +G+VT+ED++E +VGEI DE+D  
Sbjct: 272 RPIHFVPETKPVADLLKEMRDGKFHLAVVVDEYGSTAGIVTLEDLIEELVGEIHDEFDAG 331

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
            +    +L    W VR   SI+D +E  G    + E D++GGL+M   GHLP  GE +D+
Sbjct: 332 GE-GVVELGEGRWEVRGSVSIDDLSERIGEELPEGEWDSVGGLIMGLLGHLPRVGEEVDV 390

Query: 260 DGYQFKVAMADSRRIIQVHVK 280
           DG + +V      R+  V V+
Sbjct: 391 DGVRLQVRQVARHRVASVLVE 411


>UniRef50_D1C1Y5 CBS domain containing protein n=1 Tax=Sphaerobacter thermophilus
           DSM 20745 RepID=D1C1Y5_SPHTD
          Length = 424

 Score =  174 bits (441), Expect = 3e-42,   Method: Compositional matrix adjust.
 Identities = 93/238 (39%), Positives = 144/238 (60%), Gaps = 2/238 (0%)

Query: 43  DSGQNDL-IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHS 101
           + G  DL I+ED ++M+ GV+ + +  VR+IM+PR  ++   ++ ++ E +D+   + HS
Sbjct: 171 EGGNGDLDIEEDEQEMISGVLGLEEATVREIMVPRLDIVAAPQDMSISEVVDLARSAGHS 230

Query: 102 RFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQ 161
           R PV  +  D I G++ AKDLL F+   A    +  +LR A  VPESK VD +L++ R  
Sbjct: 231 RIPVYRDSIDSIVGVIYAKDLLRFVNEQATGVKLLDLLRPAYFVPESKHVDELLRDMRQA 290

Query: 162 RYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIE 221
           + H+AIV+DE+GG +GLVTIEDILE IVGEI+DEYD E  +   +L      V    +++
Sbjct: 291 KVHIAIVVDEYGGTAGLVTIEDILEEIVGEIQDEYDRETPL-IERLGAEEVIVDGRIAVD 349

Query: 222 DFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           +  + F T F++ E  TIGG V +  G +P  GE++  DG   +V   +  RI ++ V
Sbjct: 350 EIADIFETEFAEGETGTIGGFVQKRLGRIPKAGESLRADGLLIEVQAVEHHRIRKLRV 407


>UniRef50_B7IDY0 Integral membrane protein with CBS domains n=4 Tax=Thermotogaceae
           RepID=B7IDY0_THEAB
          Length = 430

 Score =  174 bits (440), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 88/234 (37%), Positives = 146/234 (62%), Gaps = 6/234 (2%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           ML+  +++ +  VR+IMIPR  ++ ++ ++TLD+ +++I E  +SR PV  E  D++ GI
Sbjct: 197 MLKRTLEMEESVVREIMIPRVDIVAIEESETLDKVMEIIKEEEYSRIPVYKETIDNVVGI 256

Query: 117 LMAKDLLPFMRSD-----AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDE 171
             AKD+L F+ SD      E   + +++R+ + VPE+ +V  +LK F+ Q+ HMAIV+DE
Sbjct: 257 CYAKDVLAFI-SDRGSEICEKVKVKELMREPLFVPETMKVSELLKIFKEQKMHMAIVVDE 315

Query: 172 FGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF 231
           +GG +GLVT+EDILE I GEI DEYD+ +++  ++L   ++ V A   I D        F
Sbjct: 316 YGGTAGLVTMEDILEEIFGEIMDEYDQNENLGIKKLENGSYIVDATVPINDIERELKIEF 375

Query: 232 SDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            + + +T+ G +++    +P  GE I ID ++FK+  A   RI +V VK+  D+
Sbjct: 376 PETDYETLAGYILEHLQRIPKVGEEIIIDKFKFKIIAASKNRIEKVLVKVVKDN 429


>UniRef50_B8J2R3 CBS domain containing protein n=3 Tax=Desulfovibrio
           RepID=B8J2R3_DESDA
          Length = 371

 Score =  174 bits (440), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 100/265 (37%), Positives = 162/265 (61%), Gaps = 7/265 (2%)

Query: 23  LSQLF-HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT 81
           LS+LF H + ++ ++ +   R  G+   ++ D   ML G++   D +V+D MIPR+ +  
Sbjct: 15  LSRLFGHDDQESLEKAILEARAEGE---VEPDEESMLLGILRFNDLQVQDTMIPRTDIDC 71

Query: 82  LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAFSMDKVLR 140
           +  +  + E   +I+ S HSR PV  E +D+I GIL AKDLL   +  + +  S+  ++R
Sbjct: 72  VPHDMPMAEVAAIIVRSGHSRIPVYKETRDNIVGILHAKDLLRSMLDGEGKVSSLAGLIR 131

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
           +   VPE+K +  +L+EFR+++ H+AI +DE+GG SGL+TIED+LE IVG+IEDE+D   
Sbjct: 132 EPFFVPETKSIRTLLQEFRARKQHIAIALDEYGGTSGLITIEDVLEEIVGDIEDEHDTPR 191

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
           + D R +  + + +   A +ED  E  G     +EVDTIGG +    GH+PA GE+  + 
Sbjct: 192 EEDIRPVGDNIYELTGRALLEDL-EDMGVDLDSDEVDTIGGYLSMEAGHVPAPGESFTLR 250

Query: 261 GYQFKVAMADSRRIIQVHVKIPDDS 285
           G+ F V  AD + I+++ ++ P DS
Sbjct: 251 GWTFTVLEADRKLILRLRME-PADS 274


>UniRef50_A6LDG3 Hemolysin-related protein n=23 Tax=Bacteroidales RepID=A6LDG3_PARD8
          Length = 450

 Score =  172 bits (436), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 97/229 (42%), Positives = 143/229 (62%), Gaps = 7/229 (3%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
           ++ML  ++   ++   +IM PR  M  ++   +  E +D II+S +SR PV SE +D+I+
Sbjct: 206 KEMLAEIIKFYNKTADEIMTPRLDMEDIEIKISFREVVDFIIKSGYSRIPVYSETEDNIK 265

Query: 115 GILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGG 174
           GIL  KDLLP++    + F    ++R A  VPE+K++D +L+EFR+ + HMAIV+DEFGG
Sbjct: 266 GILYIKDLLPYI-DKPDTFRWQSLIRPAYFVPETKKIDDLLEEFRTNKIHMAIVVDEFGG 324

Query: 175 VSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD- 233
            SG+VT+EDILE IVGEI DEYD ED+  F +L+  +    A   + DF        SD 
Sbjct: 325 TSGIVTMEDILEEIVGEISDEYD-EDEQQFIRLADGSLIFEAKILLTDFFRVIDADPSDF 383

Query: 234 ----EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVH 278
               EEV+T+ GL+++  G  P R E ID   Y+F+V   D+RRI++V 
Sbjct: 384 GKLTEEVETLAGLLLEIKGDFPRRREIIDFKEYRFQVLEVDNRRILKVK 432


>UniRef50_A7C0B4 Mg2+ and Co2+ transporter CorC n=1 Tax=Beggiatoa sp. PS
           RepID=A7C0B4_9GAMM
          Length = 227

 Score =  171 bits (434), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 84/203 (41%), Positives = 142/203 (69%), Gaps = 1/203 (0%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           + +    +P+N+ +L+ L++++ +  L++ +T  M+EGV  +++  VRD+M+PRSQM+ L
Sbjct: 19  IKKTLSNQPQNKKQLMRLLQEAKRCHLLNAETLGMIEGVFKVSETPVRDVMVPRSQMVVL 78

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKVLRQ 141
           + +   +  + +I+ES HSRFPV+ E++D ++GI +AKDLL +  +++   F M  ++R 
Sbjct: 79  ELHDPPERLIKIILESGHSRFPVVGENRDDVQGIFLAKDLLEYYAKNNGNPFHMRDLMRP 138

Query: 142 AVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD 201
            V +PESKR++ +L+EFR+ R HMAIV+DE+ GV+GLVTIED++E IVGEI+DE+D +D 
Sbjct: 139 VVFIPESKRLNVLLREFRTSRNHMAIVVDEYSGVAGLVTIEDVIEQIVGEIDDEHDIDDQ 198

Query: 202 IDFRQLSRHTWTVRALASIEDFN 224
           +  +      +TV     IE+FN
Sbjct: 199 VFIKPYRNGLYTVFGQTPIEEFN 221


>UniRef50_C2BV08 HCC HlyC/CorC family transporter n=3 Tax=Mobiluncus
           RepID=C2BV08_9ACTO
          Length = 426

 Score =  171 bits (432), Expect = 4e-41,   Method: Compositional matrix adjust.
 Identities = 98/289 (33%), Positives = 164/289 (56%), Gaps = 15/289 (5%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKNRDE---------LLALIRDSGQNDLIDEDTRDMLEGV 61
           T  N    F +LLS +  G     D+         L  ++   G+ D I++  R+M+  V
Sbjct: 137 TAWNAGKPFGMLLS-IARGPSSQTDQEARDEVAEDLREMVDQMGEPDTIEDADREMIWSV 195

Query: 62  MDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKD 121
            ++    VR++M+PR  M+T++  +TLD+ L + + S++SR PVI ED D I GIL  KD
Sbjct: 196 FEMGRTLVREVMVPRVDMVTIESEKTLDKALTLFVRSSYSRVPVIGEDADDIRGILYLKD 255

Query: 122 LLPFMRSDAEAFSM--DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           +L  + SD  A  M  ++ +R+A  +PE   VD  L++ +   YHMA+++DE+G ++GLV
Sbjct: 256 VLRRVNSDPAARQMTAEQAMREAKFIPEMNLVDDTLRDMQQNSYHMAVLVDEYGLIAGLV 315

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           T+ED++E ++GE+ DE+D  +     Q    +W V A   + D N+  GT   DE+VDT+
Sbjct: 316 TLEDLVEEVIGEVSDEHDHAEKEPELQ-PDGSWIVPARLPLVDLNDLLGTEIDDEDVDTV 374

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR--IIQVHVKIPDDSP 286
           GGL+ +A G +P  G +  ++G +     A+ RR  +  + V++   +P
Sbjct: 375 GGLLTKAVGVVPLVGASATVEGLELCAVEAEGRRRQVSAISVRLVPPAP 423


>UniRef50_C3WJU6 Magnesium and cobalt efflux protein corC n=15 Tax=Fusobacterium
           RepID=C3WJU6_9FUSO
          Length = 427

 Score =  171 bits (432), Expect = 4e-41,   Method: Compositional matrix adjust.
 Identities = 86/248 (34%), Positives = 153/248 (61%), Gaps = 1/248 (0%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +++++ +       +I+ED ++M+  ++ + +   +++M PR+ M +L+  +T++E  D 
Sbjct: 171 EDIISYVNVGNAEGIIEEDEKEMIHSIVTLGETSAKEVMTPRTSMFSLEGEKTINEIWDE 230

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
           I E+  SR PV  E  D+I GIL  KDL+  ++++     + + +R A  VPE+K +  +
Sbjct: 231 ITENGFSRIPVYEETIDNIIGILYVKDLMEHVKNNELDIPIKQFVRSAYFVPETKSIIEI 290

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
           LKEFR+ + H+A+V+DE+GGV GLVTIED++E IVGEI DEYD+E+D  F++++ + + V
Sbjct: 291 LKEFRTLKVHIAMVLDEYGGVVGLVTIEDLIEEIVGEIRDEYDDEEDSFFKKIADNEYEV 350

Query: 215 RALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
            A+  IE  N+         E+ +++GGL++   G +   G+ + ID    KV   D  R
Sbjct: 351 DAMTDIETINKELELELPISEDYESLGGLIVTTTGKICEVGDEVQIDNIYLKVLEVDKMR 410

Query: 274 IIQVHVKI 281
           + +V +KI
Sbjct: 411 VSKVFIKI 418


>UniRef50_A9B0K1 Putative uncharacterized protein n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9B0K1_HERA2
          Length = 427

 Score =  170 bits (430), Expect = 6e-41,   Method: Compositional matrix adjust.
 Identities = 79/203 (38%), Positives = 130/203 (64%), Gaps = 1/203 (0%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
           RDM+EG+ + +D  VR++M+PR  ++ L    +++E L++ I + HSR P+  E  DH+ 
Sbjct: 185 RDMIEGIFEFSDTAVREVMVPRIDIVGLAATASMEEALNLFISAGHSRLPIYDESIDHVL 244

Query: 115 GILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGG 174
           G+L AKDL P +R       +  ++RQ+  VP+S +VD +++  +S++ HMAI++DE+G 
Sbjct: 245 GVLYAKDLFPLLRDGLRDAPLRSLVRQSYFVPDSIKVDDLMRALQSRKVHMAIIVDEYGS 304

Query: 175 VSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE 234
            +GLVTIED+LE IVGEI+DE+D E+    +Q+  H W      SI+  N+A      ++
Sbjct: 305 TAGLVTIEDLLEEIVGEIQDEFDSEEA-PIQQVGPHEWLFDGRVSIDAVNDATELTLIND 363

Query: 235 EVDTIGGLVMQAFGHLPARGETI 257
           +VD++GG V+   G +P  G+ I
Sbjct: 364 DVDSLGGFVLSMLGSMPKVGDVI 386


>UniRef50_Q5SKB4 Hemolysin-related protein n=3 Tax=Thermus RepID=Q5SKB4_THET8
          Length = 445

 Score =  169 bits (427), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 90/248 (36%), Positives = 145/248 (58%), Gaps = 2/248 (0%)

Query: 29  GEPKNRDELLALIRDSGQ-NDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           G P   +E L LI    + +  I+    +M+  ++++ +  VR+IM PR +M+ ++   T
Sbjct: 182 GTPLVSEEELKLILAGAEESGAIEPQEEEMIHSILELEETPVREIMTPRVEMVAIEDEAT 241

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF-MRSDAEAFSMDKVLRQAVVVP 146
           L++ L +  E  +SR PV  E  DHI G+   +DLL +    D +AF +  +      VP
Sbjct: 242 LEDLLALYREHRYSRVPVYRESVDHIVGVAYVQDLLTYYCEEDLKAFKVASIAHPPYFVP 301

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           E+     +LKE R ++ HMAIV+DEFGG +GLVT+ED++E IVGEI DE DE ++   R 
Sbjct: 302 ENMDAWSLLKELRRRKVHMAIVVDEFGGTAGLVTLEDVIEEIVGEIYDESDEPEEHPIRL 361

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
           L    ++++A   I++ +EA G    + E DT+ G +   FG +P+ GE+++  G++F V
Sbjct: 362 LPDGAYSIQAQTPIDEVSEALGVELPEGEYDTLSGFLYALFGRIPSVGESLEWQGFRFVV 421

Query: 267 AMADSRRI 274
             AD RR+
Sbjct: 422 ESADQRRL 429


>UniRef50_Q1K126 CBS domain protein n=2 Tax=Desulfuromonadales RepID=Q1K126_DESAC
          Length = 282

 Score =  168 bits (426), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 94/282 (33%), Positives = 167/282 (59%), Gaps = 5/282 (1%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           T   ++ +   LL    H    + + L  LI  S +  +I+ +  +M   + +  +  VR
Sbjct: 4   TPETRRSWLQRLLGITHHV--TSEEHLQELIHASEEGGIINAEEGEMFSSIFEFGETIVR 61

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           ++MIPR++M +   + +LD  ++++++  HSR PV  E  D I G++ AKDLL F    +
Sbjct: 62  EVMIPRTEMRSCPVDASLDTFIEMVLKFGHSRIPVYEETIDRIVGLVYAKDLLKFWGQPS 121

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
              S+  ++R+   VPE+KR++ +L+EFR+QR H+AI IDE+GG SGL+T+ED++E I+G
Sbjct: 122 HEISLRDLMRKPYFVPETKRIEELLQEFRTQRMHIAIAIDEYGGTSGLITLEDLIEEIIG 181

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG-THFSDEEVDTIGGLVMQAFGH 249
           +I+DEYD  DD    + +  T  V A  S+++  + +    F  ++ D++GGL++   G+
Sbjct: 182 DIKDEYD-FDDNQLIEETPGTIVVDARLSLDELEDHYDLPEFERDQFDSVGGLLLHRLGY 240

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           +P  GE + ++  +  V  +D R I ++ V I ++SP+  LD
Sbjct: 241 VPKPGEEVVVEPLKMVVLQSDERMIHRIRV-IREESPEEPLD 281


>UniRef50_A9WFQ5 CBS domain containing protein n=4 Tax=Chloroflexaceae
           RepID=A9WFQ5_CHLAA
          Length = 450

 Score =  168 bits (425), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 103/286 (36%), Positives = 153/286 (53%), Gaps = 12/286 (4%)

Query: 16  KGFFSLLLSQLFHGEPKNRDELLALIRDSGQN-DLIDEDTRDMLEGVMDIADQRVRDIMI 74
           +  F+LL  Q     P   +E L L+  +G+    I+ + R+M+EGVMD  D  VR+IMI
Sbjct: 154 RPIFTLLSGQPAPPTPLVTEEELRLMMSAGEKAGWIEHEEREMIEGVMDFGDTLVREIMI 213

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR  ++ L+ N  L   LDV I   HSR PV  E  D++ GIL  KDL+P +R       
Sbjct: 214 PRVDVVALEVNSPLKRALDVAITRGHSRIPVYEETIDNVVGILYVKDLIPVLRDGKHDTP 273

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +  +LR A  VP + +V  +L++ + +R HMAIV+DE+GG +G+VT+ED++E IVGEI D
Sbjct: 274 LRDLLRPAYFVPVTMKVAALLEDLQRRRVHMAIVVDEYGGTAGIVTLEDLIEQIVGEIRD 333

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARG 254
           EYD E+     ++  +   V A   I+D        F +   D IGGLV +  G +P  G
Sbjct: 334 EYDTEEP-AIVEVGPNELIVDARVPIDDVAGLLEVEFPETTADRIGGLVYEQLGRIPREG 392

Query: 255 ET-----IDIDGYQFKVAMADSRRII-----QVHVKIPDDSPQPKL 290
           +      + I     K   A+  RI+     ++    P D+ +P L
Sbjct: 393 DQVVCNDVTITVLSIKGIRAERLRIVRQAPAEITAAAPVDAEKPLL 438


>UniRef50_B2S3N8 Hemolysin n=5 Tax=Spirochaetaceae RepID=B2S3N8_TREPS
          Length = 265

 Score =  167 bits (423), Expect = 4e-40,   Method: Compositional matrix adjust.
 Identities = 82/225 (36%), Positives = 139/225 (61%), Gaps = 2/225 (0%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           ++E+ +DM+ G++D++D  VR++MIPR  +  L+ + + +  ++ + ES HSRFPV  + 
Sbjct: 21  LNEEKQDMIRGIVDLSDTSVREVMIPRIDVDFLELSMSGETLVEKVTESGHSRFPVYEQT 80

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVI 169
            D++ G+L  KDL+       E   ++++LR+   VPESKR+D +L+EF+ +  H+AI +
Sbjct: 81  IDNVVGVLYVKDLIKLFGRPQEV-RLERLLRKPFFVPESKRIDSLLREFKRRHVHIAIAV 139

Query: 170 DEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT 229
           DE+GGVSG+  +EDI+E IVG+I+DE+D E + D   L +  W   A   +ED +E   T
Sbjct: 140 DEYGGVSGIACMEDIIEEIVGDIQDEFDHERE-DIEPLGQGVWLCDARVDLEDLSECLHT 198

Query: 230 HFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
            F  +E  T+GG V   FG +P + E +    + F +   ++ +I
Sbjct: 199 VFPSQEFGTLGGFVFNLFGKIPVKYEKVSWGAFDFIIQDMEAHKI 243


>UniRef50_C8XF87 CBS domain containing protein n=11 Tax=Bacteria RepID=C8XF87_NAKMY
          Length = 537

 Score =  167 bits (422), Expect = 5e-40,   Method: Compositional matrix adjust.
 Identities = 93/229 (40%), Positives = 140/229 (61%), Gaps = 3/229 (1%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           EL  L+  +G   +++E  R+ML+ V D+ D  VR++M+PR++ + ++R++TL + L + 
Sbjct: 165 ELRELVDIAGSRGVVEETEREMLQSVFDLGDTIVREVMVPRTETVWIERDKTLRQALALA 224

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLL-PFMR--SDAEAFSMDKVLRQAVVVPESKRVD 152
             S  SR PV+ ED D I G+   KDL+ P M    D +   + +++R+ V VPESK VD
Sbjct: 225 SRSGMSRIPVVGEDLDDIVGVAYLKDLIAPAMNLAPDDQGPVLTQIMREPVFVPESKNVD 284

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+E +  R H A+V+DE+GG +G+VTIEDILE IVGEI DEYD +       L   ++
Sbjct: 285 DLLREMQRDRTHFAVVVDEYGGTAGIVTIEDILEEIVGEITDEYDADTPAPVVPLPDGSF 344

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDG 261
            V A   +ED  E F     D+EVDT+GGL+ Q  G +P  G  + + G
Sbjct: 345 RVSARLPVEDLGELFDVELDDDEVDTVGGLLAQQLGRVPLPGSEVGVAG 393


>UniRef50_C1A944 Transporter n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A944_GEMAT
          Length = 432

 Score =  166 bits (420), Expect = 9e-40,   Method: Compositional matrix adjust.
 Identities = 96/257 (37%), Positives = 149/257 (57%), Gaps = 4/257 (1%)

Query: 32  KNRDELLALIRDSGQNDL-IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDE 90
           + R+E  A  RD    +  +  D R++L GV D  +    ++M+PR  +  ++R     E
Sbjct: 167 ERREEAAAQFRDVVTTEADVSRDERELLLGVFDFGETTAEEVMVPRVDITGVERETPWSE 226

Query: 91  CLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE-AFSMDKVLRQAVVVPESK 149
            LD I  + HSR PV     D I GIL  KD+LP + +D E A     V+R  V +P SK
Sbjct: 227 MLDRIRSAEHSRIPVYEGSIDEIVGILYVKDVLPAVLADEEPAEGWTSVMRSPVFIPTSK 286

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
           R+  +L+EFR  R H+AIV DE+GG +GLVTIED+LE +VGEI DEYD+E+ +   +   
Sbjct: 287 RIADLLREFRQARRHIAIVADEYGGTAGLVTIEDVLEELVGEIGDEYDDEERLVESEEGT 346

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
             W V    +++D ++A    F+ ++V T+GGLV++  G +P  GE++ I  ++  V   
Sbjct: 347 RYW-VSGRLTLDDLSKALSHDFTRDDVSTVGGLVLELLGRVPKAGESLTIGPFRAIVERV 405

Query: 270 DSRRIIQVHV-KIPDDS 285
             R+I +V + ++PD +
Sbjct: 406 VRRKIERVFLERVPDTT 422


>UniRef50_D1B5K7 Putative uncharacterized protein n=1 Tax=Thermanaerovibrio
           acidaminovorans DSM 6589 RepID=D1B5K7_THEAS
          Length = 426

 Score =  165 bits (418), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 85/248 (34%), Positives = 141/248 (56%), Gaps = 2/248 (0%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
            R+E+  ++++   +  ++E+ R M+ G++   + RV +IM+PR+ ++ +    T+ + +
Sbjct: 169 TREEIDHMVKEGSASGALEEEERKMIHGIISFEETRVSEIMVPRTDVVAVVAGSTVRDAV 228

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
            + ++S HSR P+   D DH+ GIL  KDLL  +        ++   R  + VPE+ R+ 
Sbjct: 229 RIFMDSGHSRMPIYEGDMDHVVGILYVKDLLRNLTQGDMDRPVEDCKRDCLFVPETMRIG 288

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +    +  R HMA+V+DE+GG +GLVT+ED+LE IVGEI+DEYDEE  I   Q     +
Sbjct: 289 ELFDRMKKARVHMAVVVDEYGGTAGLVTLEDLLEEIVGEIQDEYDEE--IPPIQEEGGVF 346

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V+    +ED +EA G  F  E+VDT+ G V+   G  P  G+ I  D +  +V      
Sbjct: 347 VVQGHVHLEDLSEALGHQFQAEDVDTVAGFVLSILGAFPEEGQGILYDDWSIEVTKVQGH 406

Query: 273 RIIQVHVK 280
           RI++V  +
Sbjct: 407 RIMEVRFR 414


>UniRef50_B9L251 Magnesium and cobalt efflux protein corC n=1 Tax=Thermomicrobium
           roseum DSM 5159 RepID=B9L251_THERP
          Length = 420

 Score =  165 bits (418), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 89/224 (39%), Positives = 134/224 (59%), Gaps = 1/224 (0%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           ++E V+ +     RDIM+PR+ ++ +    ++ + + V  ++ HSR PV     D I GI
Sbjct: 183 LIERVLRLDRLTARDIMVPRTDIVAVPFELSVRDAIAVARQTRHSRLPVYQGTIDRIVGI 242

Query: 117 LMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           +  +DLL F    AE   +  V+R+A  +PESKRVD +L++ + QR HMAIV+DEFGG +
Sbjct: 243 VHVRDLLRFALESAEGIKVGDVMREAYFIPESKRVDELLRDLQHQRVHMAIVVDEFGGTA 302

Query: 177 GLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEV 236
           G+VTIED+LE IVGEI+DEYD E  +   +LS     V    S+E+  + FG    +EE 
Sbjct: 303 GIVTIEDVLEEIVGEIQDEYDAEAPL-VERLSADEAIVDGRISLEEIADIFGVSLEEEES 361

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
            TIGGLV    G +P  GE++ +DG +  V      R+ ++ V+
Sbjct: 362 STIGGLVQAHLGRIPQPGESVRVDGLEVTVLEVAGNRVRKLSVR 405


>UniRef50_C6BSI1 CBS domain containing protein n=2 Tax=Desulfovibrio
           RepID=C6BSI1_DESAD
          Length = 272

 Score =  164 bits (416), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 87/243 (35%), Positives = 143/243 (58%), Gaps = 2/243 (0%)

Query: 41  IRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAH 100
           I ++ ++  I E+   ML  V+++ D    +IMIPR+ MI ++ + +L +  + IIE  H
Sbjct: 28  ILEASEDGEIKEEVVSMLLNVLELKDTEAHEIMIPRTDMIGVEVSSSLSDVAEEIIEHGH 87

Query: 101 SRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFR 159
           SR PV  E KD I GIL AKD++ P +R   +   ++ ++R+     E  +V  +L EF+
Sbjct: 88  SRIPVFKETKDRIVGILHAKDIIAPLLRGKTDT-PLEDIMRKPFFASEHIKVKTLLTEFQ 146

Query: 160 SQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALAS 219
           + R H+AI+ DE+GG SGL+T+ED+LE IVG+I DE+D +   DF +L    + +     
Sbjct: 147 TGRIHLAILQDEYGGTSGLITMEDVLEEIVGDISDEHDADRPSDFNELENGKFLISGRVP 206

Query: 220 IEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           + + +E        E V++IGG + +  G +P  GE I+I GY+F V   D+++II + +
Sbjct: 207 LTEVSERLNLSLDSEHVESIGGYISELTGRIPHVGEFINISGYKFTVHEGDAKQIISILI 266

Query: 280 KIP 282
             P
Sbjct: 267 DPP 269


>UniRef50_UPI0001BCCCA8 CBS domain-containing protein n=1 Tax=Aeromicrobium marinum DSM
           15272 RepID=UPI0001BCCCA8
          Length = 438

 Score =  164 bits (415), Expect = 3e-39,   Method: Compositional matrix adjust.
 Identities = 89/241 (36%), Positives = 145/241 (60%), Gaps = 4/241 (1%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           E+  L+  +  + LI+ D   M++ V ++ D  VR++M+PR+ ++ +++++TL + + + 
Sbjct: 171 EVRELVDLAAASSLIESDESKMIQSVFELGDTIVREVMVPRTDIVFIEQHKTLRQSMSLA 230

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLLP--FMRSDAE-AFSMDKVLRQAVVVPESKRVD 152
           + S +SR PV+ ++ D + G+   KD+    F    AE A  +  +LR  + VP++K  D
Sbjct: 231 LRSGYSRLPVVEDNLDDVVGMAYLKDVTKRVFDNHTAEHAERVSSILRPCLFVPDTKHAD 290

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +LKE ++QR H+AIV+DEFGG +G+VTIEDILE IVGEI DEYD E D +   L   +W
Sbjct: 291 ELLKEMQAQRTHVAIVVDEFGGTAGMVTIEDILEEIVGEITDEYDTEPD-ELEVLVDGSW 349

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V +   ++D  E  G    DE+VD++GGL+ +  G +P  G  I I+G +        R
Sbjct: 350 RVSSRYDVDDLAELTGVDLQDEDVDSVGGLLAKHLGKVPIPGSAIVIEGLRLVAEAPSGR 409

Query: 273 R 273
           R
Sbjct: 410 R 410


>UniRef50_C6W2S8 CBS domain containing protein n=1 Tax=Dyadobacter fermentans DSM
           18053 RepID=C6W2S8_DYAFD
          Length = 438

 Score =  164 bits (414), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 92/235 (39%), Positives = 137/235 (58%), Gaps = 6/235 (2%)

Query: 52  EDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKD 111
           E+  D+L G+ +      R  M  R Q+          E +D I +S +SR PV  +D D
Sbjct: 204 EEETDLLRGLANFRQTIARKAMQARVQITAFDIELDFHELMDRINKSGYSRVPVYRDDLD 263

Query: 112 HIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDE 171
           H+EGIL  KDLLP +  D E F+  K+LR    +PESKR+D ++K+F+++R HMAIV+DE
Sbjct: 264 HVEGILNVKDLLPHIHLD-EHFNWQKLLRPVYFIPESKRLDDLMKDFQNRRVHMAIVVDE 322

Query: 172 FGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG--T 229
           +GG SGL+T+EDI+E I G+I DEYDE++++++ Q+  HT+       I D        T
Sbjct: 323 YGGTSGLITLEDIIEEIFGDINDEYDEDEEVNYTQVDEHTYVFEGKVLINDLCRLLNLET 382

Query: 230 HFSDE---EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
            + DE     +++ GL+++ F  LP  GE        FKV  AD +RI +V V +
Sbjct: 383 DYFDEVRGNSESLAGLLLELFSRLPRTGEIATHREVTFKVQSADKKRIKKVRVLV 437


>UniRef50_D1VUR6 CBS/transporter domain protein n=1 Tax=Peptoniphilus lacrimalis
           315-B RepID=D1VUR6_9FIRM
          Length = 439

 Score =  164 bits (414), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 88/260 (33%), Positives = 153/260 (58%), Gaps = 6/260 (2%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  + +EL + I+ S +  +I+    DM+  +MD  D+   +IM PR+ +  +  ++   
Sbjct: 179 EQISEEELKSYIKVSQEQGVINSTGEDMIINIMDFDDKMAYEIMTPRTAIFMVDYDEFSV 238

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDL-LPFMRSDAEAFSMDKVLRQAVVVPES 148
           + +  I+ + +SR PV  E+ D+I GI+  KDL + + +++ + F++DK L+    VPE+
Sbjct: 239 DSISEILATGYSRMPVYRENADNIIGIINIKDLFIEYEKNNYKNFNLDKCLKTPYFVPET 298

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K++DR+LKE ++ + ++AI+IDE+GG SG+VT+EDI+E IVGEIEDEYD        ++ 
Sbjct: 299 KKIDRLLKELQTSKNYVAILIDEYGGFSGMVTVEDIVEEIVGEIEDEYDRNTP-SMEKIG 357

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET----IDIDGYQF 264
            + + V    +IED NE   T    E  +TI GL+++  G++P   E     +  +G   
Sbjct: 358 PNEYMVDGYMTIEDINEELDTKLFSENHETISGLIIEKLGYIPEENEKKKLQVKTNGVML 417

Query: 265 KVAMADSRRIIQVHVKIPDD 284
            V     +RI++  +KI D+
Sbjct: 418 TVLAIKDKRIVKAALKILDN 437


>UniRef50_C2MBP5 Gliding motility-associated protein GldE n=1 Tax=Porphyromonas
           uenonis 60-3 RepID=C2MBP5_9PORP
          Length = 452

 Score =  164 bits (414), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 90/238 (37%), Positives = 138/238 (57%), Gaps = 11/238 (4%)

Query: 51  DEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDK 110
           D    +M+  ++    +   +IM+PR  MI +  +    + L   +++ +SR PV    +
Sbjct: 201 DNKETEMIHEIVKFYHKTADEIMVPRVDMIGVNYHWAYHQTLSFAVDTGYSRLPVYDGSQ 260

Query: 111 DHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVID 170
           D I G+L  KDLLP M  + + F   K++RQA  VPE+K++D +L+E + +R HMAIVID
Sbjct: 261 DSIRGVLYVKDLLPHMHEE-DTFPWQKIIRQAYFVPENKKIDTLLEELQQERIHMAIVID 319

Query: 171 EFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN------ 224
           EFGG SGL+T+EDILE IVGEI DEYD+ED   + +L+   + +    S+ D        
Sbjct: 320 EFGGTSGLITLEDILEEIVGEIVDEYDDEDP-PYVRLAEGVYLIDGGMSLIDLCKLLDVE 378

Query: 225 -EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
            E F  H+  EEVDT+GGL ++    +P  G+ I I    F V   +  RI+Q+ +++
Sbjct: 379 PEYFAPHY--EEVDTVGGLFLEVLQEIPQVGQQITISDIDFIVTRMERHRIMQLKMRL 434


>UniRef50_A8KYW4 CBS domain containing protein n=33 Tax=Actinomycetales
           RepID=A8KYW4_FRASN
          Length = 484

 Score =  162 bits (411), Expect = 9e-39,   Method: Compositional matrix adjust.
 Identities = 92/236 (38%), Positives = 136/236 (57%), Gaps = 3/236 (1%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
           RDM+  V ++ D  VR++M+PR  M+ ++ ++T+ + + + + S  SR PVI E  D + 
Sbjct: 189 RDMIASVFELGDTLVREVMVPRPDMVFIESDKTVRQAISLALRSGFSRIPVIGESIDDVV 248

Query: 115 GILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGG 174
           GI   KD++ + R   E+  + +V+R  V+VPESK  D +L+E ++ R HMAIVIDE+GG
Sbjct: 249 GIGFLKDMVGWEREGRESSRVAEVMRPPVLVPESKPADDLLREMQASRTHMAIVIDEYGG 308

Query: 175 VSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH--FS 232
            +GLVTIED+LE IVGEI DEYD         L   T  V A   ++D  + FG      
Sbjct: 309 TAGLVTIEDVLEEIVGEITDEYDSATP-PVEWLDDDTARVTARLDVDDLADLFGVEELPG 367

Query: 233 DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
            ++V+T+GGL+  A G +P  G T D+ G +     A  RR     V +   SP P
Sbjct: 368 AQDVETVGGLLANALGRVPIPGATADVAGLRLSAERAAGRRNQIGTVVVHRLSPAP 423


>UniRef50_A7HLR9 Putative uncharacterized protein n=1 Tax=Fervidobacterium nodosum
           Rt17-B1 RepID=A7HLR9_FERNB
          Length = 443

 Score =  162 bits (411), Expect = 1e-38,   Method: Compositional matrix adjust.
 Identities = 93/240 (38%), Positives = 139/240 (57%), Gaps = 6/240 (2%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           ID +   M+E  + + +  V++IMIPR  ++ ++  QTL E ++VIIE  +SR PV  + 
Sbjct: 187 IDHEEGLMVERTIAMDETLVKEIMIPRIDVVAVEETQTLGEVINVIIEEEYSRIPVYRDT 246

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFSMDKV-----LRQAVVVPESKRVDRMLKEFRSQRYH 164
            D++ GI  AKD+L F+        M+KV     +R  + VPE   V  +LKEF+S++ H
Sbjct: 247 IDNVVGICYAKDILSFIAQRGSDV-MNKVRVKELMRPPLFVPEVMPVSELLKEFKSKKVH 305

Query: 165 MAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN 224
           MAIV+DE+GG +G+VT+EDILE I GEI DEYDE +    ++L   T+ V A  S+ D  
Sbjct: 306 MAIVVDEYGGTAGIVTMEDILEEIFGEIMDEYDEHESTGIKKLDDFTYLVDATLSLNDIE 365

Query: 225 EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
                 F + E +T+ G ++  F H+P  GE  +     +KV  A   RI +V +KI  D
Sbjct: 366 RELRIEFPEGEFETLAGYLLDKFHHIPKVGEQYEDSNITYKVVAASRNRIEKVLMKINVD 425


>UniRef50_Q1AX40 Putative uncharacterized protein n=1 Tax=Rubrobacter xylanophilus
           DSM 9941 RepID=Q1AX40_RUBXD
          Length = 442

 Score =  162 bits (409), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 89/257 (34%), Positives = 145/257 (56%), Gaps = 1/257 (0%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  + +EL  +I  S  + ++D + RD L  V D  D+  R++M+PR  ++ L  + +  
Sbjct: 182 EVHSEEELRIMISSSAASGVLDPEERDYLNNVFDFGDRVAREVMVPRPDIVALSSDLSPQ 241

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
           E +       ++R+PV   D DH+ G++  KD+          F + K++R A+VVPE+K
Sbjct: 242 EMVQEAAFGRYTRYPVYEGDLDHVLGVVHVKDIFRASLESPGGFDVRKIVRDALVVPENK 301

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            ++++L+EF+ ++  MAIVIDE+G V GLVTIED+LE IVGEI+DE+DEE+     +L  
Sbjct: 302 PIEQLLREFQRRKLQMAIVIDEWGSVEGLVTIEDVLEEIVGEIQDEFDEEEA-RIEELGG 360

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
             + V     I + NE F      E+ +TIGG V+   G  P  G+ ++ DG   +V   
Sbjct: 361 GLYAVDGRIPIVEVNEFFELDLPHEDFETIGGYVLGTLGRPPRPGDVVEADGATLQVKSV 420

Query: 270 DSRRIIQVHVKIPDDSP 286
           D  R+  + ++  + SP
Sbjct: 421 DGPRVSMLTLRRKERSP 437


>UniRef50_A1QYK9 Magnesium and cobalt efflux protein CorC n=21 Tax=Borrelia
           RepID=A1QYK9_BORT9
          Length = 259

 Score =  162 bits (409), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 88/219 (40%), Positives = 129/219 (58%), Gaps = 2/219 (0%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           +L+    + +  V++IMIPR  ++ +  + + DE L V+  S HSRFPV  E  D I GI
Sbjct: 31  LLKNFNSLKETIVKEIMIPRISVVFVDYSWSKDEILKVVTSSNHSRFPVYRETIDDIIGI 90

Query: 117 LMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGV 175
           +  KD+L  M + D     +  ++R+ + VPESK++D +LKEF+    H+AIV+DE+GGV
Sbjct: 91  IHTKDILLHMWKRDFYEIDLRDIMRKVMFVPESKKIDSLLKEFQENHVHIAIVVDEYGGV 150

Query: 176 SGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE 235
           +GLVT+EDILE IVG+I+DE+D E D +   L   ++   A   IED NE  G    D +
Sbjct: 151 AGLVTLEDILEEIVGDIQDEFDNELD-EIVPLDDGSYLCTARVLIEDLNEKLGLSLPDGD 209

Query: 236 VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
            DT+GG V   FG +P + E I  +   F +     R I
Sbjct: 210 FDTLGGFVYDLFGRIPLKNEKIKYNNLTFTIKNMHQRNI 248


>UniRef50_A5CRB2 Conserved membrane protein n=4 Tax=Actinobacteria (class)
           RepID=A5CRB2_CLAM3
          Length = 440

 Score =  161 bits (408), Expect = 2e-38,   Method: Compositional matrix adjust.
 Identities = 85/261 (32%), Positives = 155/261 (59%), Gaps = 10/261 (3%)

Query: 22  LLSQLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           L +++  G PK      + ++LL+++ ++ + ++++ED R+++  + +  D  VR++MIP
Sbjct: 145 LGNRVTPGRPKTVATFTSEEQLLSMVDEATELEVLEEDDRELIHSIFEFNDTVVREVMIP 204

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS---DAEA 132
           R+ M+ +++   +   L + +    SR PV   D D IEG+L  +DL   +     +AE 
Sbjct: 205 RTDMVVVEQTAHVGSALGLFLSRGISRAPVTGRDSDEIEGVLYLRDLARMVYERPEEAER 264

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
            ++D++ R AV VPES++ D +L++ + +  H+A+V+DE+GG++GLVT+ED++E +VG+I
Sbjct: 265 TTVDQLARPAVFVPESQKADALLRQMQLESNHLAMVVDEYGGIAGLVTLEDLIEELVGDI 324

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DEYD  D  +F  L    + V A   I++  + FG    D++VD+ GGL+ +  G LP 
Sbjct: 325 SDEYD-RDVPEFEDLGDGVYRVSARLPIDELGDLFGLELDDDDVDSAGGLLAKTLGRLPE 383

Query: 253 RGETIDIDGYQFKVAMADSRR 273
           RG  + + G        + RR
Sbjct: 384 RGSVVRVGGLVLTADRVEGRR 404


>UniRef50_B5YFP5 CBS domain protein n=1 Tax=Thermodesulfovibrio yellowstonii DSM
           11347 RepID=B5YFP5_THEYD
          Length = 432

 Score =  160 bits (406), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 86/246 (34%), Positives = 148/246 (60%), Gaps = 3/246 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           +++EL  LI +  +  + + D R ++      A+  V++IM+P  QM+T+    +++E  
Sbjct: 179 SQEELKLLIEEGEEKGIFEPDERQLIHSAFSFAEITVKEIMVPAPQMVTVSIYMSVNEIK 238

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
           ++I++   SR+P + +D + I GIL AKD    +  + +   + ++L+  + VPE+ +++
Sbjct: 239 EIIMDEKFSRYPALGKDLNDIRGILHAKDFYNALIKNPDLLDIKRLLKPPMFVPETMKIN 298

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +LKE + +R HMAIV+DE+G V+GLVT+EDILE +VGEI DEYD E  +    L   + 
Sbjct: 299 ILLKEMQKKRVHMAIVVDEYGVVTGLVTLEDILEELVGEIRDEYDIEMPVI--TLPDGSM 356

Query: 213 TVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
            + A  SI D  E +G    + EE DT+GG ++ +   +P  G+T+D+DG  FKV     
Sbjct: 357 IIDATISIRDLKEDYGIEIEESEEYDTLGGFILTSLQRIPHVGDTVDMDGKIFKVIEMVG 416

Query: 272 RRIIQV 277
           +RI ++
Sbjct: 417 QRISKI 422


>UniRef50_D1Y8K5 Putative transporter n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y8K5_9BACT
          Length = 430

 Score =  160 bits (405), Expect = 4e-38,   Method: Compositional matrix adjust.
 Identities = 88/262 (33%), Positives = 144/262 (54%), Gaps = 7/262 (2%)

Query: 22  LLSQLFH------GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
             S LFH           RDE+  L+++  ++  I+   R M++GV+   + RV +IM+P
Sbjct: 150 FFSDLFHVDMTLESAVVTRDEIEQLVKNGEESGAIEASERRMIDGVIAFDETRVSEIMVP 209

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  M  L+ N+T+     ++    HSR PV  E  D I G++  KD++P++R+      +
Sbjct: 210 RVSMDALEVNETIAGVASLMQNWEHSRIPVFRETPDDIVGVVYLKDMIPYLRAGKMDTPL 269

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
              +R+A+ VPE+ +V  +    R +  H A+V+DE+GG +G+VT+ED+LE IVG+I DE
Sbjct: 270 SAFMRRALFVPETMKVADLFGMMRGKHVHFAVVVDEYGGTAGIVTLEDLLEEIVGDIRDE 329

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
           YDEE      QL+ +++ V+   S+ED     G  F   +VD++GG V+  F   P +G+
Sbjct: 330 YDEESA-PIVQLNENSYRVKCTESLEDLGAVVGYDFDCNDVDSVGGYVLDKFMGFPEKGD 388

Query: 256 TIDIDGYQFKVAMADSRRIIQV 277
               D +  KV      R+ +V
Sbjct: 389 IYRDDDWTIKVTDVGEHRVNEV 410


>UniRef50_P67130 UPF0053 protein Rv2366c/MT2435 n=36 Tax=Actinomycetales
           RepID=Y2366_MYCTU
          Length = 435

 Score =  160 bits (405), Expect = 5e-38,   Method: Compositional matrix adjust.
 Identities = 84/223 (37%), Positives = 136/223 (60%), Gaps = 4/223 (1%)

Query: 46  QNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPV 105
           Q  ++  D R M+E V ++ D   R++M+PR++MI ++ ++T  + + + + S HSR PV
Sbjct: 177 QRGVVAADERRMIESVFELGDTPAREVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPV 236

Query: 106 ISEDKDHIEGILMAKDLL--PFMRSDA-EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQR 162
           I E+ D I G++  KDL+   F  ++     ++ +V+R AV VP+SK +D +L+E +  R
Sbjct: 237 IGENVDDIVGVVYLKDLVEQTFCSTNGGRETTVARVMRPAVFVPDSKPLDALLREMQRDR 296

Query: 163 YHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIED 222
            HMA+++DE+G ++GLV+IED+LE IVGEI DEYD+ +      L    + V A   IED
Sbjct: 297 NHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVSARLPIED 356

Query: 223 FNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQF 264
             E +G  F D+ +VDT+GGL+    G +P  G  +   G + 
Sbjct: 357 VGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRL 399


>UniRef50_D1AFV9 Putative uncharacterized protein n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1AFV9_SEBTE
          Length = 428

 Score =  160 bits (405), Expect = 5e-38,   Method: Compositional matrix adjust.
 Identities = 79/253 (31%), Positives = 159/253 (62%), Gaps = 2/253 (0%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H E    DE++ L+ ++ ++ L++++   +++ V +++++ V  +MIPR+ M  +     
Sbjct: 176 HEEIHTNDEIMLLLTENYKHGLLNKEELTLVDNVFELSEKNVMSVMIPRTDMQCIYMGDN 235

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           L++ +D +++  ++R+PV  E+KD+I G +  +DL   +  + E   ++ ++R+ + VP+
Sbjct: 236 LEKIMDFVLDGKYTRYPVCRENKDNIIGFVHIRDLCKQVILNTEN-DIEDIMREIIFVPD 294

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  V+ + K F+     +AIVIDE+GG +GLVT+EDILE +VGEI+DE+D  D  + +++
Sbjct: 295 TMSVNALFKRFQEDHSQIAIVIDEYGGTAGLVTLEDILEELVGEIQDEFDINDVSEIKKI 354

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
           S   ++V    +I+  N+    +  + +V+TIGGL    +G LP  GE I  DGY+F + 
Sbjct: 355 SDTVYSVDGKVTIDRINKLLNINI-ETKVETIGGLFSLEYGSLPEAGEKIIHDGYEFTII 413

Query: 268 MADSRRIIQVHVK 280
            ++++R+++V ++
Sbjct: 414 KSNNKRVLRVKIE 426


>UniRef50_Q6ZUX1 cDNA FLJ43252 fis, clone HEART2006909 n=23 Tax=cellular organisms
           RepID=Q6ZUX1_HUMAN
          Length = 307

 Score =  160 bits (404), Expect = 6e-38,   Method: Compositional matrix adjust.
 Identities = 85/233 (36%), Positives = 137/233 (58%), Gaps = 7/233 (3%)

Query: 52  EDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKD 111
           +D + ML+G++   D+  +++M  R  ++ L  + T  E L  I E+ +SR PV  ++ D
Sbjct: 71  KDEQSMLKGIIRFGDETAKEVMTSRQNIVDLDIHSTYPEVLKCIAENNYSRIPVYQDNTD 130

Query: 112 HIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDE 171
           +I GIL  KDLLP +     +F    ++R    VPE+K++D +L+EF+  + H+AIV+DE
Sbjct: 131 NIRGILYIKDLLPHLEKPV-SFRWQSLIRPPYFVPETKKIDDLLREFQENKVHIAIVVDE 189

Query: 172 FGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF 231
           FGG SG+VT+EDILE IVGEI DEYDEE+   + +L+ +T+       + DF +      
Sbjct: 190 FGGTSGIVTLEDILEEIVGEINDEYDEEEKF-YSKLNYNTFIFEGKTLLTDFCKILNVDD 248

Query: 232 SDE-----EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
            +      + DT+ GL+++  G  P+  E I+   Y F+V   + RRI ++ V
Sbjct: 249 EEFEEVEGDADTLAGLLLEIKGDFPSIHEKIEYKNYSFEVLGVEERRISRIKV 301


>UniRef50_A6CBK3 Hemolysin protein n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CBK3_9PLAN
          Length = 436

 Score =  160 bits (404), Expect = 6e-38,   Method: Compositional matrix adjust.
 Identities = 90/254 (35%), Positives = 150/254 (59%), Gaps = 7/254 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+L+++ +  +  +++ +   M++ VM++ D+ V  IM  R  M  +  N TLDE L  
Sbjct: 171 EEILSVVEEGARGGILESEAGKMIQRVMELQDEDVGAIMTQRMDMEYISVNATLDEALLK 230

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD------AEAFSMDKVLRQAVVVPES 148
            I+  HSR PVI E  D I GIL A++LL     +       E  ++ K++     +PE+
Sbjct: 231 FIDVGHSRIPVIGESTDDIVGILYARELLKHFSKENQNSESPEELTIQKLMFSPFYIPET 290

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             +D +L+  + +  HMAIVIDE+GGV+GLVT+ED+LE IVG+I DE+DEE++    +  
Sbjct: 291 TGIDSLLETMQKEHVHMAIVIDEYGGVAGLVTMEDVLEEIVGDIVDEFDEEEEQMIFETG 350

Query: 209 RHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
           ++T  V A   I+D NE +  +  + ++ DTIGG V+   G +P  GET+     + +V 
Sbjct: 351 QNTLEVDARVHIDDLNEQYNYNLPEGKDFDTIGGFVITQIGKVPQPGETLTWQQLRIEVL 410

Query: 268 MADSRRIIQVHVKI 281
            +D RRI ++ +++
Sbjct: 411 ESDERRINKLRIEL 424


>UniRef50_Q1DCR5 CBS/transporter associated domain protein n=2 Tax=Cystobacterineae
           RepID=Q1DCR5_MYXXD
          Length = 455

 Score =  159 bits (403), Expect = 7e-38,   Method: Compositional matrix adjust.
 Identities = 82/230 (35%), Positives = 140/230 (60%), Gaps = 2/230 (0%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           +D+    ++  + +++D+R RD+M+PR++++T+    T DE L ++ E  HSR PV  +D
Sbjct: 194 VDKSAPQLIRSIFELSDKRCRDVMVPRTEVVTVDVTITPDELLRLLAEENHSRIPVYRDD 253

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVI 169
            DH+ G+L A+D++P ++   E   +  ++R A  VP  K +  +L++ + Q+ HMAIV+
Sbjct: 254 VDHVIGVLHARDIIPLLQ-HPELIVLQDIIRPAHFVPWMKPIGDLLRDMQKQKIHMAIVV 312

Query: 170 DEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT 229
           DE+GG  G+VT+EDIL  IVG+I DE++ E+     +L+  ++ V A   ++ F + FG 
Sbjct: 313 DEYGGFMGVVTLEDILREIVGDIGDEFEVEEK-QVEKLADGSFLVDAALEVDAFTQTFGF 371

Query: 230 HFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
              + + DT+GG +    GHLP  GE     G+QF VA  +  RI +V +
Sbjct: 372 PLPEGDFDTLGGFLSSMAGHLPDVGERFAYSGWQFVVASKEGPRIDRVRM 421


>UniRef50_Q11NU6 Hemolysin-related protein, with CBS domain; gliding motility
           protein n=1 Tax=Cytophaga hutchinsonii ATCC 33406
           RepID=Q11NU6_CYTH3
          Length = 293

 Score =  159 bits (403), Expect = 8e-38,   Method: Compositional matrix adjust.
 Identities = 88/252 (34%), Positives = 146/252 (57%), Gaps = 7/252 (2%)

Query: 43  DSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR 102
           +S +  L   + ++M+ G++   +  V+ IM PR  M  +      ++  + I     SR
Sbjct: 44  ESAKGTLSTREEKEMIRGLVKFGNIMVKQIMCPRMDMAAVDIALNYEQLQEYISTCGFSR 103

Query: 103 FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQR 162
            PV  E  D IEG+L  KDL PF   + + F+  +++R    +PE+K ++ +L+EF+ + 
Sbjct: 104 IPVYKESADKIEGVLNIKDLFPFYNKEKD-FNWQQLIRTVEFIPETKLIEELLREFQLKH 162

Query: 163 YHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIED 222
            HMAIV+DE+GG +GL+T+ED++E IVG+I DEYD +D+  + QLS  ++      S+ D
Sbjct: 163 LHMAIVVDEYGGTAGLITMEDVIEEIVGDIHDEYD-DDEKPYAQLSDTSYLFEGKISLVD 221

Query: 223 FNEA--FGTHFSDE---EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQV 277
           F +A        DE   E +T+GGL++     LP  G+ I  +GY FK+   +S+RI++V
Sbjct: 222 FYKAIELDKDIFDEVKGESETLGGLLLNINSDLPRLGDEIIYEGYVFKIDAVNSKRILRV 281

Query: 278 HVKIPDDSPQPK 289
            V +P++S   K
Sbjct: 282 KVTVPENSENEK 293


>UniRef50_C0K042 Hemolysin-related protein n=1 Tax=uncultured bacterium 34R1
           RepID=C0K042_9BACT
          Length = 353

 Score =  159 bits (403), Expect = 9e-38,   Method: Compositional matrix adjust.
 Identities = 87/247 (35%), Positives = 144/247 (58%), Gaps = 6/247 (2%)

Query: 40  LIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA 99
           L R    +DL   D ++ML G++   D+ V +IM PR  ++ L      D+ +  ++E+ 
Sbjct: 98  LSRALEASDLKSTDEKEMLRGILTFGDKTVSEIMRPRVDVVDLDIELGFDDVVKAVVENG 157

Query: 100 HSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFR 159
           +SR PV  E+ D+I+GIL AKDLLP++    + F    ++R A  VPES+ +D +L++FR
Sbjct: 158 YSRMPVYEENPDNIKGILYAKDLLPYIGKKDDTFKWQSLMRPAYFVPESRMIDDLLEDFR 217

Query: 160 SQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALAS 219
            ++ HMA+++DEFG   G+ T+ED+LE IVG+I+DEYD E+   F +++ +T+   A   
Sbjct: 218 KKKIHMAVIVDEFGCTQGIATLEDVLEEIVGDIDDEYDTEEKY-FTRVAENTYIFDAKTP 276

Query: 220 IEDFNEAFG---THFSD--EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
           ++DF EA      +F+D  +E +T+ GL++   G      E +      F V      RI
Sbjct: 277 LDDFFEATCIDENNFADHLDEAETLAGLLLSLKGDFLKEKEELKTAPCTFTVLKVKKYRI 336

Query: 275 IQVHVKI 281
            +V V++
Sbjct: 337 AKVKVEV 343


>UniRef50_C6L9Q9 CBS domain protein n=6 Tax=Clostridiales RepID=C6L9Q9_9FIRM
          Length = 424

 Score =  159 bits (401), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 85/256 (33%), Positives = 144/256 (56%), Gaps = 4/256 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G+    +EL   +  S ++ +I+++ + M+  V D  D + +DIMIPR +M+++  N + 
Sbjct: 164 GDVMTENELRTYVDVSHEDGVIEQEEKQMIYNVFDFGDTQAKDIMIPRVEMVSIDVNASY 223

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
            E L V  E   +R PV  E  D++ G+L  KD + F   D  +F M  ++R+     E 
Sbjct: 224 QEVLKVFREEKFTRLPVYEESTDNVIGVLNIKDFIFF---DENSFDMRSMMREPNFTYEY 280

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K    ++ + R    +  IV+DE+G  +GL+T+ED+LE IVGEI DEYD++++   +++S
Sbjct: 281 KSTSELMDQMRQSSVNFTIVLDEYGATAGLITLEDLLEEIVGEIRDEYDKDEEELIKKIS 340

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI-DGYQFKVA 267
              + +     ++D N+A       E+ D+IGGL++    HLPA GE++   DG +  V 
Sbjct: 341 DREYILPGFMKLDDVNDALDLLLHSEDYDSIGGLIIGELDHLPAVGESVTTPDGIRLVVE 400

Query: 268 MADSRRIIQVHVKIPD 283
             D  RI QVH+ +P+
Sbjct: 401 AVDKNRINQVHLYLPE 416


>UniRef50_C7GAD7 CBS domain protein n=9 Tax=Bacteria RepID=C7GAD7_9FIRM
          Length = 426

 Score =  159 bits (401), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 93/275 (33%), Positives = 146/275 (53%), Gaps = 9/275 (3%)

Query: 19  FSLLLSQLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           FS+    L H +PK        +EL  ++  S +N +I+ +  +M+  + D  D + +++
Sbjct: 148 FSMGFLFLLHVDPKANNNQMTEEELRTIVDVSKENGVIESEEHEMINNLFDFGDAQAKEV 207

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           MIPR  M     N T DE +D+  E   +R PV  +  D++ GIL  KDLL  +  D E 
Sbjct: 208 MIPRPDMTFANVNNTYDELIDIFQEDKFTRLPVYEDTTDNVIGILNMKDLL--LCKDKEH 265

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
           FS+  ++R+     E K    +  E R     +AIV+DE+G  +GL+T+ED+LE IVGEI
Sbjct: 266 FSVRDIMREPYFTFEHKNTAELFIEMRKSSISLAIVLDEYGATAGLITLEDLLEEIVGEI 325

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DEYD +++     L+   + V    +++D  +    +FS E+ DTIGG ++    HLP 
Sbjct: 326 RDEYDTDEEDPILPLNDREFIVSGSTNLQDLCDELDLNFSSEDYDTIGGYLLGLLDHLPE 385

Query: 253 RGETIDI-DGYQFKVAMADSRRIIQVHVKIPDDSP 286
           + E I   D    +V   D  RI +V++K PD  P
Sbjct: 386 KNEIIITDDNVLLRVEQMDKNRIEKVYIKKPDFPP 420


>UniRef50_C0W0A3 HCC HlyC/CorC family transporter n=1 Tax=Actinomyces coleocanis DSM
           15436 RepID=C0W0A3_9ACTO
          Length = 429

 Score =  158 bits (399), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 85/241 (35%), Positives = 142/241 (58%), Gaps = 3/241 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+  ++ + G+    +E+ R+ML  V ++    VR++M+PR++M+T+    T+DE LD+
Sbjct: 171 EEMREVVDEVGETSGFEEEDREMLRSVFELGYTLVREVMVPRTEMVTIAAETTIDEALDL 230

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFM--RSDAEAFSMDKVLRQAVVVPESKRVD 152
            + S +SR PVI +D D I GI+  KD++  +  R D +   +  V R+   VPE    D
Sbjct: 231 FVTSGYSRIPVIEDDIDDIVGIVYFKDVISRLRRRPDDKQVPVRNVCREPRFVPEVVLAD 290

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
             L++ ++ R H+A+V+DE+GG++GLVTIED+LE IVGE+ DE+D  +     ++S   W
Sbjct: 291 DELRQMQASRVHLALVVDEYGGIAGLVTIEDLLEEIVGELTDEHD-RNVTQPEEISEGVW 349

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V A  S+ +  E  G    DE+VD++GG + +  G +P  G++ + D        A  R
Sbjct: 350 RVPARFSLWELGELLGVELEDEDVDSVGGYLAKLLGKVPLPGDSAETDDIMITAEEAVGR 409

Query: 273 R 273
           R
Sbjct: 410 R 410


>UniRef50_C9KMQ2 CBS domain protein n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KMQ2_9FIRM
          Length = 445

 Score =  157 bits (398), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 102/279 (36%), Positives = 159/279 (56%), Gaps = 6/279 (2%)

Query: 6   SHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIA 65
           +H ++ ++++ GF +       H E    +E+  L+ +S +  LID+   D ++ V D  
Sbjct: 161 NHVANWVAHRMGFHTASEGDDAHTE----EEIRLLMEESHRQGLIDDTEVDFVDNVFDFT 216

Query: 66  DQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF 125
           D  VR+IM PR+ M+ L    T++E L  I+E   +R+P+  EDKDHI G L  KDL+  
Sbjct: 217 DLNVREIMTPRTDMVCLYLEDTMEENLHTILEEQLTRYPICHEDKDHIVGFLHVKDLMRI 276

Query: 126 MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDIL 185
           M ++    ++ ++ R+A++VPES  V  +LK  + QR  MAIV+DE+GG +G+VTIEDI+
Sbjct: 277 M-AEGRKPNLRRLARKALIVPESMDVSVLLKTMQKQRSQMAIVVDEYGGTAGMVTIEDIV 335

Query: 186 ELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQ 245
           E IVG+I+DE+DEE     R+  R  ++V A   +E+  +       DE+VDTIGG +  
Sbjct: 336 EEIVGDIQDEFDEERPTAERRGKR-IFSVDAKMLLEELEDILEIDIEDEDVDTIGGWLYD 394

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
             G  P  G+     G  F V   D  RI +V +   +D
Sbjct: 395 QIGQTPRVGQMAASGGNLFYVEEVDGVRITRVLIHCAED 433


>UniRef50_A1AQM4 CBS domain containing protein n=9 Tax=Desulfuromonadales
           RepID=A1AQM4_PELPD
          Length = 296

 Score =  157 bits (398), Expect = 3e-37,   Method: Compositional matrix adjust.
 Identities = 90/277 (32%), Positives = 155/277 (55%), Gaps = 5/277 (1%)

Query: 4   DNSHSSDTISNKKGFFSLLLSQLFHGEPK-NRDELLALIRDSGQNDLIDEDTRDMLEGVM 62
           D      TI++  G F L   +  HG  K    E+  LI+ S    +++E+  +M+  + 
Sbjct: 13  DTLEEGSTITS--GIFKLF-ERFVHGRKKMTAYEIQDLIKASEDEGVVNEEESEMIRSIF 69

Query: 63  DIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL 122
            +    VR++M+PR  M  +  + T+ E L+ I+   HSR PV     D++ G+L AKD+
Sbjct: 70  SLRSTVVREVMVPRIDMACISVDATVREILETILACGHSRIPVFENSVDNVIGLLYAKDM 129

Query: 123 LPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIE 182
           L +     +   +  ++R    +PE+K ++++L+EF+++  H+AIVIDE+GG SGL+TIE
Sbjct: 130 LKYWGLSEDLIRVRSIMRPPYFIPETKNLEQLLQEFKNKHVHLAIVIDEYGGTSGLITIE 189

Query: 183 DILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGL 242
           D+LE IVG+I+DE+D E+ + F      + T  A   IE+  + F      ++ DT+GGL
Sbjct: 190 DLLEQIVGDIQDEHDREEAL-FTTNDDGSLTADARLPIEELEQLFDMEIEHDKFDTVGGL 248

Query: 243 VMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           +    G + A G+T++ +     V  +D R+I +V +
Sbjct: 249 IFHLTGKISAPGDTVENEQLVIAVLDSDERKIKRVCI 285


>UniRef50_C1ZDU6 CBS domain-containing protein n=1 Tax=Planctomyces limnophilus DSM
           3776 RepID=C1ZDU6_PLALI
          Length = 439

 Score =  157 bits (397), Expect = 4e-37,   Method: Compositional matrix adjust.
 Identities = 91/268 (33%), Positives = 152/268 (56%), Gaps = 11/268 (4%)

Query: 28  HGEPKN------RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT 81
            GEP+        DE+  ++ +  +   +++  R M+  VM++ D+ V  IM PR+ M +
Sbjct: 162 RGEPEEDDASVLSDEIRTVVDEGQREGYLEQGARVMIHRVMELQDEDVGGIMTPRTDMFS 221

Query: 82  LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK---V 138
           +    +L+E    +I S HSR PV+++  D I G+L +KDLL  +       S+ K   +
Sbjct: 222 IPLGASLEEARQKLISSGHSRVPVVADSPDEIVGLLYSKDLLKALDPACARDSLPKLSEI 281

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           LR+   +PE+  +  +L+  + + + +AIV+DE+GGV+GLVT+EDILE IVGEI DEYD 
Sbjct: 282 LREPKYIPETTGIAALLEMMQREHFQLAIVLDEYGGVAGLVTMEDILEEIVGEIADEYDT 341

Query: 199 -EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGET 256
            E +   ++++ +   + A   I+D NE F      D E DTIGG V    G +P+ GE 
Sbjct: 342 LEGESPVKKIAPNIVEIDARMHIDDLNEQFLYGLPEDGEFDTIGGFVFSQLGRMPSTGEI 401

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDD 284
            D +  +  +  AD R+I+++ ++ P +
Sbjct: 402 FDWNNLKMTIIEADKRKILRLRIEQPSE 429


>UniRef50_B8CXI7 Putative membrane CBS domain protein n=1 Tax=Halothermothrix orenii
           H 168 RepID=B8CXI7_HALOH
          Length = 420

 Score =  157 bits (397), Expect = 4e-37,   Method: Compositional matrix adjust.
 Identities = 87/250 (34%), Positives = 140/250 (56%), Gaps = 4/250 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + +E+   +  S +  +I  D R M+  + +  D  V++IM+PR  M+ +K +  L E +
Sbjct: 161 SEEEIKRFVNVSEEEGVIKTDERRMINSIFEFDDTTVKEIMVPRIDMVCIKSDTELSEVI 220

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
            + ++  HSR PV     D I G++  KDLL ++        +   +R    VPESK+++
Sbjct: 221 KIAVDRGHSRIPVYKNTIDEIIGVVYVKDLLGYLTKPENDARLADFIRSPYYVPESKKIN 280

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE-DDIDFRQLSRHT 211
            +L E + ++ HMAIV+DE+GG SGLVTIEDILE IVG+I+DEYD E   I+F  ++   
Sbjct: 281 ELLTEMKKKKVHMAIVLDEYGGTSGLVTIEDILEEIVGDIQDEYDTEPSQIEF--INDKE 338

Query: 212 WTVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
             + A   I+D NE        EE  +TI G ++   G++P  GE +++DG    V  + 
Sbjct: 339 LLIDARVDIDDLNEILPEPLPGEEDYETISGFILHYLGYVPKTGEELELDGLHILVEESS 398

Query: 271 SRRIIQVHVK 280
             +I +V +K
Sbjct: 399 KHQIKKVRLK 408


>UniRef50_A3HUW6 Hemolysin-related protein, containing CBS domain n=2
           Tax=Sphingobacteriales RepID=A3HUW6_9SPHI
          Length = 449

 Score =  157 bits (397), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 86/237 (36%), Positives = 143/237 (60%), Gaps = 10/237 (4%)

Query: 52  EDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKD 111
           E+ RD+L+G+++     V+ +M  R  +  +  +    E +D I +S  SR PV  E  D
Sbjct: 203 EEERDILKGIVNFGTLTVKQVMRSRMDITAVDEDMDFHELMDKINKSGFSRIPVFQETID 262

Query: 112 HIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDE 171
           +I GIL  KDLLPF+  D E F+ + ++R++  VPE+K+VD +LK+F+ +R HMAIV+DE
Sbjct: 263 NISGILYIKDLLPFIERD-EDFNWNDLIRKSYFVPENKKVDTLLKDFQLKRVHMAIVVDE 321

Query: 172 FGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF 231
           +GG SGLVT+ED++E I+GEI DE+D+ DD+ F+++  +T+      S+ DF +      
Sbjct: 322 YGGTSGLVTLEDLIEEIIGEINDEFDDTDDVFFQEIDTNTFIFEGKVSLNDFCKKL--EL 379

Query: 232 SDEEVDTIGG-------LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
             +  D + G       L+++    LP  G  I  + ++F +   D+R+I +V V++
Sbjct: 380 DAQMFDEVKGENESLGGLLLELNSKLPKNGTKIHFEEFEFTILAVDARKIKKVKVRL 436


>UniRef50_B5YET1 GldE n=2 Tax=Dictyoglomus RepID=B5YET1_DICT6
          Length = 377

 Score =  157 bits (397), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 88/249 (35%), Positives = 144/249 (57%), Gaps = 5/249 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           DE L L+    +  +I+++ ++++  V++  D  V +IM+PR  M+ +  +  L E    
Sbjct: 116 DEFLTLVNVGEKEGIIEKEEKELISNVLEFTDTEVHEIMVPRIDMVCVSVDSPLKEVWKK 175

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
           IIE  HSR PV     D+I GI+ AKD+L  +        +  +LR  + VPE+ +++ +
Sbjct: 176 IIEEGHSRIPVYEGSIDNIVGIVHAKDVLKALAEKDPNVKIKDILRDVIYVPENMKINEL 235

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
             E R ++ H+AIV+DE+GG +GLVT+ED+LE +VGEIEDEYD+E++  F  L  +T  V
Sbjct: 236 FNEMRKKKAHLAIVVDEYGGTAGLVTLEDVLEELVGEIEDEYDKEEN-KFNFLDENTLIV 294

Query: 215 RALASIEDFN----EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
            A  +I + N    E +G    + E DT+GGL++     +P+RGE ID+      +    
Sbjct: 295 DAKMNIYELNDILEETWGITLPETEYDTLGGLILDLLNRVPSRGEQIDLGDLIIVIESVR 354

Query: 271 SRRIIQVHV 279
            +RI +V +
Sbjct: 355 RQRIEKVKI 363


>UniRef50_Q1NMM8 CBS:Transporter-associated region n=2 Tax=Deltaproteobacteria
           RepID=Q1NMM8_9DELT
          Length = 301

 Score =  157 bits (396), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 84/236 (35%), Positives = 140/236 (59%), Gaps = 2/236 (0%)

Query: 46  QNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPV 105
           ++ LI  +  +M+ G+M++ D    +IM PR++M+ ++   TL   + +IIE  +SR PV
Sbjct: 54  EHGLISPEEGEMISGIMELKDTLAYEIMTPRAEMVLVEAATTLPAMVALIIERGYSRIPV 113

Query: 106 ISEDKDHIEGILMAKDLLPF-MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYH 164
             ED D I G++ AKD+LP+ ++ + E  + + + +    +PE + V R+LK F+  + H
Sbjct: 114 YREDPDQIIGLVHAKDILPYCLQPEGEPPNAESLAKPVEFIPEKRGVLRLLKFFQENKIH 173

Query: 165 MAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN 224
           +A+V DEFGGV GLVT+EDI+E IVG+I DE+D      ++ + + T    A   IE+  
Sbjct: 174 LAVVNDEFGGVRGLVTLEDIVEEIVGDINDEHDRITR-RWKVVDQRTVLADAKVDIEEVE 232

Query: 225 EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
           E F     +   +++GGL++     +P  G T+ ID   F+V  AD RR+I V ++
Sbjct: 233 EFFKIELPEGPYESVGGLILHHLDRVPPPGVTLSIDSLVFEVLAADKRRVITVKIQ 288


>UniRef50_C0GM71 CBS domain containing protein n=1 Tax=Desulfonatronospira
           thiodismutans ASO3-1 RepID=C0GM71_9DELT
          Length = 270

 Score =  157 bits (396), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 80/235 (34%), Positives = 145/235 (61%), Gaps = 2/235 (0%)

Query: 40  LIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA 99
           +IR++ +   I  +   ML  ++ + +++  +IM+PR+ ++  + N TL +  + I++S 
Sbjct: 28  VIREASEEGEIKNEEVRMLLNILRLHEKQAVEIMVPRTDLVCAEENDTLKDVAESILQSG 87

Query: 100 HSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFR 159
           HSR PV  E+KDHI G++ AKDLL     + +  S++ ++R+   +PE+K V ++L +F+
Sbjct: 88  HSRLPVYRENKDHIVGLIHAKDLLQHFFENKDV-SVNSLMREPHFMPETKNVRQILMDFQ 146

Query: 160 SQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALAS 219
           +Q+ H+ +V+DE+GG SG+VT+ED+LE IVGEIEDEYD     + + +   T+ V    S
Sbjct: 147 NQKIHLGVVLDEYGGTSGIVTLEDVLEEIVGEIEDEYDPPRPQEVQTMDDGTYYVAGRTS 206

Query: 220 IEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
           +++  +  G     E+V+TIGG +    G +P +GE    + + + V  A+++ I
Sbjct: 207 LDELAD-IGIKIPTEQVETIGGYISHLAGKVPVKGEEFSDEFFSYVVQEANTKNI 260


>UniRef50_B3WFB2 Transport protein n=8 Tax=Lactobacillus RepID=B3WFB2_LACCB
          Length = 448

 Score =  157 bits (396), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 90/265 (33%), Positives = 146/265 (55%), Gaps = 6/265 (2%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           GE   RDE++++I     +  ID D   M EG++ ++D   R++M+PR+    +   +  
Sbjct: 178 GETVTRDEMVSMIESGRNSGAIDPDEYQMFEGIISLSDTMAREVMVPRTDAFMVDAQEPD 237

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAFSMDKVLRQAVVVPE 147
              +D I+ + +SR PV  EDKDH+ GI+  K+LL   R    +   ++ V+   V VPE
Sbjct: 238 HTAIDAILNNIYSRIPVYEEDKDHVVGIVHIKNLLKEARRVGFDHVKIESVMTAPVFVPE 297

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  VD +L E + ++  MAI++DE+GGV G+VTIED+LE IVGEI+DE D+ + + F + 
Sbjct: 298 TITVDDLLTEMQVKQQQMAILLDEYGGVVGIVTIEDLLEEIVGEIDDESDQVEKL-FTKQ 356

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID---GYQF 264
             H + V     I DFN+ F T     +VDTI G V+   G +P+   +  +    G   
Sbjct: 357 GDHDFVVSGRMPISDFNDLFKTDLDAPDVDTIAGYVLTQLGAIPSSHHSEKMQLAPGVLL 416

Query: 265 KVAMADSRRIIQVHVKIPDDSPQPK 289
                +  R++ VH+ +  + P P+
Sbjct: 417 ATGKVEGSRLVNVHIHLSSE-PVPE 440


>UniRef50_A6WDG0 CBS domain containing protein n=1 Tax=Kineococcus radiotolerans
           SRS30216 RepID=A6WDG0_KINRD
          Length = 438

 Score =  157 bits (396), Expect = 5e-37,   Method: Compositional matrix adjust.
 Identities = 90/259 (34%), Positives = 146/259 (56%), Gaps = 9/259 (3%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           EL  ++  +G+  +I+   R M+  V ++ D  VR++M+PR+ +++ +R   L E   ++
Sbjct: 170 ELREIVELAGETSVIEAGERRMINSVFELGDTLVREVMVPRTDVVSARRGAGLHEVEALL 229

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD---AEAFSMDKVLRQAVVVPESKRVD 152
           + S  SR PVI ED D + GI+  KD+     +D   A A  ++ V RQ V VP+S  VD
Sbjct: 230 LRSGFSRMPVIGEDADEVLGIVYLKDVARRFHTDPVAARAERVETVARQTVFVPDSLPVD 289

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L++ +    H+AIV+DE+GG +GLVTIED++E IVG+I DEYD     D   L    +
Sbjct: 290 ELLRQMQRDTTHVAIVVDEYGGTAGLVTIEDVIEEIVGDIADEYDRAAP-DVEPLPDGGF 348

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQF----KVAM 268
            V +   +ED  E F     DE+VDT+GGL+ +  G +   G   ++ G +     +V  
Sbjct: 349 RVSSRLHVEDLGELFEKEIEDEDVDTVGGLLAKTLGEVLVPGAVAEVHGLRLEADARVGR 408

Query: 269 ADSRRIIQVHVKIPDDSPQ 287
            +  R + VH ++P+  P+
Sbjct: 409 RNQVRTVLVH-RLPEHEPE 426


>UniRef50_Q6MCC0 Putative uncharacterized protein n=2 Tax=Parachlamydiaceae
           RepID=Q6MCC0_PARUW
          Length = 457

 Score =  157 bits (396), Expect = 6e-37,   Method: Compositional matrix adjust.
 Identities = 82/239 (34%), Positives = 142/239 (59%), Gaps = 8/239 (3%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           +D   + ++EGVMD  D+  R++M+PR  + +L  + T+++   +I    +SR PV    
Sbjct: 205 LDPHDKKLIEGVMDFKDRIAREVMVPRVDIFSLAHDTTIEQAAVLIYNEGYSRIPVFKHT 264

Query: 110 KDHIEGILMAKDLLP----FMRS-DAEAFS--MDKVLRQAVVVPESKRVDRMLKEFRSQR 162
            D+I G+LM KD+L     F R+ D +     +  +++  +  PE+K++  +L+EFR ++
Sbjct: 265 LDNIIGVLMYKDVLAKYMEFSRTQDTKILQAPISGLVKNVLYTPETKKISHLLQEFRKKQ 324

Query: 163 YHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIED 222
            H+AI++DE+GG  G+VTIEDILE IVG+I DEYDE ++  F  L    W + A  +I D
Sbjct: 325 VHLAIIVDEYGGTEGIVTIEDILEEIVGDIADEYDESEESLFVALPEGGWLIDARMTIFD 384

Query: 223 FNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
             E F    + D + DTIGG +    G++P++G  +    ++ KV  ++ RR+ ++ ++
Sbjct: 385 IEEQFDIEIAQDGDYDTIGGYIFHETGNIPSKGFVLTKPNFELKVIRSNDRRVEKLKIR 443


>UniRef50_C4V614 TlyC family hemolysin n=14 Tax=cellular organisms
           RepID=C4V614_9FIRM
          Length = 447

 Score =  156 bits (394), Expect = 9e-37,   Method: Compositional matrix adjust.
 Identities = 90/251 (35%), Positives = 146/251 (58%), Gaps = 6/251 (2%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
             +E+  L+++S +  LI+    D ++ V    +   R+IM+PR+ MI L  + +  E +
Sbjct: 184 TEEEIRLLMKESYRQGLINSTEADFVDKVFSFTELNAREIMVPRTDMICLYLDDSPAERI 243

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPESKRV 151
             I+E   +R+PV  EDKDHI G +  KDLL P MR   E  ++ + +R+A++VPES   
Sbjct: 244 KTILEEQQTRYPVCYEDKDHIIGFIHVKDLLAPLMR--GEQLNLRRYIRKALIVPESMDG 301

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD-EEDDIDFRQLSRH 210
             +L+  + Q Y +AIV+DE+GG +G+VT+EDI+E IVG+I DE+D E + +++R L   
Sbjct: 302 SILLRTMQEQGYQLAIVVDEYGGTAGMVTVEDIIEQIVGDIRDEFDVERESVEWRDLD-- 359

Query: 211 TWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
             ++ A   +E+ N+  G    DE+VD+IGG +    G  P  G+    +G    V   D
Sbjct: 360 ICSIDAKLLLEEVNDLLGIRIEDEDVDSIGGWLYDQLGEAPRVGQMAAHEGALLYVEEVD 419

Query: 271 SRRIIQVHVKI 281
             RI +V V++
Sbjct: 420 GIRITRVLVRL 430


>UniRef50_B8J8L5 CBS domain containing protein n=4 Tax=Anaeromyxobacter
           RepID=B8J8L5_ANAD2
          Length = 425

 Score =  156 bits (394), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 90/254 (35%), Positives = 148/254 (58%), Gaps = 4/254 (1%)

Query: 27  FHGEPKNRDEL-LALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRN 85
           F   P   DE+  AL   +G+     E TR+++  V +  ++  RD+M+PR+ ++ ++  
Sbjct: 164 FSLPPPPLDEMERALAEYAGRGGSGSEGTRELIHNVFEFREKVARDVMVPRTDVVAVELG 223

Query: 86  QTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVV 145
             + + +  + E  HSR PV  E  D I G+L A+DL+P + +  E   +  +LR A  V
Sbjct: 224 TPVPQIIRTLSEEGHSRMPVYRESLDQIAGVLHARDLVPLL-AHPELIVLADILRPAHFV 282

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED-EYDEEDDIDF 204
           P SK V+++L+E + +  HMA V+DEFGGV G+ TIED+LE IVG+I+D   +E++  + 
Sbjct: 283 PWSKPVEQLLREMQRRHLHMAFVVDEFGGVMGICTIEDVLEQIVGDIQDEFEEEDEGREV 342

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
            Q +  ++TV+  A++ +FN A       D+  +T+ G V    G +PARG+     G+ 
Sbjct: 343 EQHADGSFTVQGAAAVAEFNRAAQAGVPEDQGFETMAGFVSSLAGAIPARGDRFFWKGWV 402

Query: 264 FKVAMADSRRIIQV 277
           F VA AD RR+++V
Sbjct: 403 FTVAEADPRRVVKV 416


>UniRef50_C0W312 HCC HlyC/CorC family transporter n=1 Tax=Actinomyces urogenitalis
           DSM 15434 RepID=C0W312_9ACTO
          Length = 432

 Score =  155 bits (393), Expect = 1e-36,   Method: Compositional matrix adjust.
 Identities = 83/241 (34%), Positives = 145/241 (60%), Gaps = 3/241 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           ++L  +I + G+ + I+++ R ML  V+++    VR++M+PR+ M+T+  ++ +   + +
Sbjct: 168 EDLREMIDEIGEAETIEDEDRQMLRSVVELGQTLVREVMVPRTDMVTIDADKPVSAAMRL 227

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV--LRQAVVVPESKRVD 152
            I+S  SR PVI +D D + G++  KDLL  + +  E    + V  +R+AV VPE+K  D
Sbjct: 228 FIKSGFSRVPVIGQDADDVRGVVYLKDLLRRLDAQPEYAQREVVTCMREAVYVPETKLAD 287

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+E ++   HMA+ +DE+GG +GLVT+ED+LE +VG++ DE+D  +  +   L    +
Sbjct: 288 DLLREMQTDSVHMALAVDEYGGTAGLVTMEDLLEEVVGDMTDEHDHAEP-EVEDLGDGVY 346

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V A  S+++  E FG    D++VDT GGL+ +A G +P  G + ++ G       A  R
Sbjct: 347 RVPARLSLDELGELFGLEIDDDDVDTAGGLLTKAIGRVPLPGASGEVQGLHLVADQATGR 406

Query: 273 R 273
           R
Sbjct: 407 R 407


>UniRef50_C9MVS3 CBS domain protein n=3 Tax=Fusobacteriaceae RepID=C9MVS3_9FUSO
          Length = 450

 Score =  154 bits (390), Expect = 2e-36,   Method: Compositional matrix adjust.
 Identities = 82/254 (32%), Positives = 155/254 (61%), Gaps = 9/254 (3%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  +++EL +L+    ++ +I+E  ++M+E +++  ++  R+IMIPR+++  + +N ++ 
Sbjct: 178 EKVSKEELRSLVEVGKEHGVINETEQEMIENIIEFDEKIAREIMIPRTKVFLIDKNISIH 237

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV---LRQAVVVP 146
           E  +      +SR PV   + D+I G+L+ KDL+  M +  + F   KV   L++A  VP
Sbjct: 238 ELFENKEIGKYSRIPVYENEADNIVGVLLTKDLM--MEAYKKGFDNIKVADLLQEAYFVP 295

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           E+K V+ +  E + ++ H+ I+IDE+GG SG+VT+ED++E ++G I DE+D+E D+  RQ
Sbjct: 296 ETKNVNELFNEMQLEKKHITILIDEYGGFSGIVTLEDLIEEVMGNIADEFDDE-DLSIRQ 354

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETID---IDGYQ 263
           LSR+ + +    S+ D N+ F      +  DT+ G++++  G++P   E I+   I+G  
Sbjct: 355 LSRNKYLISGEVSLNDLNDNFNFELESKYYDTLSGILIENLGYIPEDNENIEPITINGVV 414

Query: 264 FKVAMADSRRIIQV 277
           FK     +++I +V
Sbjct: 415 FKPQRVRNKKIEKV 428


>UniRef50_Q47RN3 CBS domain protein n=1 Tax=Thermobifida fusca YX RepID=Q47RN3_THEFY
          Length = 439

 Score =  154 bits (389), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 94/254 (37%), Positives = 145/254 (57%), Gaps = 12/254 (4%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G     +EL  L+  + +  +ID + R M+  V  + D  VR++MIPR  ++ L+ N ++
Sbjct: 165 GPFATEEELRHLVDLAERGHVIDPEERQMIHSVFQLDDTTVREVMIPRPDIVFLEGNVSI 224

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR--------SDAEAFSMDKVLR 140
           +E L+  + S +SR PVI E  D + GI+  KDL+  +         + A   ++  V+R
Sbjct: 225 EEALEKALSSGYSRIPVIGESLDDVIGIVYLKDLVARLYDAWRANGGAPAPGRTIRDVMR 284

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE- 199
           +   VP+SK VD +L+E + QR H+A+VIDE+GG +G+VTIEDI+E IVGEI DEYD+E 
Sbjct: 285 EPTYVPDSKPVDELLREMQQQRIHLAVVIDEYGGTAGIVTIEDIVEEIVGEITDEYDDEV 344

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
             I++   +R   T R    + +  E FG      +VDT+GGL+  A G +P  G   + 
Sbjct: 345 PPIEWLDDNRARVTAR--LPLGELAELFGVEIDAPDVDTVGGLLAYALGRVPVPGSQAEY 402

Query: 260 DGYQFKVAMADSRR 273
            G +  VA   +RR
Sbjct: 403 AGLRL-VAEDPARR 415


>UniRef50_B8G2E5 Putative uncharacterized protein n=3 Tax=Clostridiales
           RepID=B8G2E5_DESHD
          Length = 437

 Score =  154 bits (388), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 82/254 (32%), Positives = 146/254 (57%), Gaps = 6/254 (2%)

Query: 24  SQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLK 83
           S L H E    +EL  L+  S ++ ++D+    +L+ V + +D+ V ++M+PR  M+ L 
Sbjct: 167 SDLAHTE----EELRMLVDASQRHGILDKMEGKLLDNVFEFSDRVVSEVMVPRQDMMCLY 222

Query: 84  RNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAV 143
              +++E L+ +  S H+R+P+  +DKD++ G++  +DLL    S++   ++ ++ R  +
Sbjct: 223 IQDSMEEVLETVKTSGHTRYPLCDDDKDNVIGLVHMRDLLSL--SESSVKNIGELKRDIL 280

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
           +VPE   +  ++++ R QR H+A+V+DEFGG +G+VTIED++E +VGEI DE++  +  +
Sbjct: 281 IVPEGMPISHLVQKMRVQRTHLAVVVDEFGGTAGMVTIEDLIEELVGEIYDEFESAEQAE 340

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
             +     + +     ++D +E     F DE V TIGG V    G  P +G+ ID   Y 
Sbjct: 341 IIKSGESEYLINGRVLLDDLSELLAVEFEDETVSTIGGFVFNRLGRKPVKGDRIDFMDYT 400

Query: 264 FKVAMADSRRIIQV 277
           F V      RI +V
Sbjct: 401 FTVMEVVGFRITRV 414


>UniRef50_Q73QX2 CBS domain protein n=1 Tax=Treponema denticola RepID=Q73QX2_TREDE
          Length = 439

 Score =  153 bits (387), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 88/246 (35%), Positives = 132/246 (53%), Gaps = 16/246 (6%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
           + +LE ++   D  V++IM PR  +I L  +   +E +++   S  SRFPV  ED D I 
Sbjct: 192 KAVLEKILSYGDITVKNIMTPRPDIIGLTADVNPEEIIELSHSSRFSRFPVYEEDIDEII 251

Query: 115 GILMAKDLL-------PFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAI 167
           GI   KD L        F++   E F + K LR+ V+V E+  + ++ + FR ++ +M +
Sbjct: 252 GIFYIKDFLFSEAAAKDFLQESKEKFDIKKYLRKPVLVFENTELSKLQEIFRKEKQNMVV 311

Query: 168 VIDEFGGVSGLVTIEDILELIVGEIEDEYDEE---------DDIDFRQLSRHTWTVRALA 218
           VIDE+GG  G+ T+ED+ E I G I DEYD +         D+I+  +    + T+    
Sbjct: 312 VIDEYGGTLGIATLEDLNEEIFGNIADEYDTDDAAAEDPNLDNINDEETQNLSQTILGSM 371

Query: 219 SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVH 278
            + D NE  GT FS E  DTIGGL+M+  G +P  G TI I+ Y F V   +  RI ++ 
Sbjct: 372 RLSDLNENLGTSFSSEYYDTIGGLIMEKCGEVPQIGSTIKIENYNFTVMKTEGNRISELQ 431

Query: 279 VKIPDD 284
           V I  D
Sbjct: 432 VNIAGD 437


>UniRef50_A0JX40 CBS domain containing protein n=4 Tax=Micrococcaceae
           RepID=A0JX40_ARTS2
          Length = 447

 Score =  153 bits (387), Expect = 6e-36,   Method: Compositional matrix adjust.
 Identities = 87/244 (35%), Positives = 146/244 (59%), Gaps = 4/244 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + +E   L+  + ++D+I+++  ++++ V D  D  VR +M+PR+ ++++    +L   +
Sbjct: 163 SEEEFRELVDRATESDMIEDNEAELIQSVFDFGDTLVRAVMVPRTDILSIDAGSSLHRAM 222

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDL---LPFMRSDAEAFSMDKVLRQAVVVPESK 149
            + + S +SR PVI ++ D I GI+  KD+   L  +    E   +D + R+   VPESK
Sbjct: 223 SLFLRSGYSRIPVIRDNTDQILGIIYLKDVAAALHGLGPGEEPPIVDDLAREVRYVPESK 282

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
           +V  +L+E + +  H+AIVIDE+GG +GLVT+ED++E IVGEI DEYD E   +   L  
Sbjct: 283 QVSDLLRELQKESTHVAIVIDEYGGTAGLVTLEDLIEEIVGEIVDEYDTESA-EAVALGN 341

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
            ++ V A   I+D  E F     D+EVDT+GGL+ +A G +P  G T+++DG   +    
Sbjct: 342 GSYRVSARMGIDDLGELFDVELDDDEVDTVGGLLAKALGRVPIVGSTVEVDGISLRAERL 401

Query: 270 DSRR 273
           + RR
Sbjct: 402 EGRR 405


>UniRef50_B4CWQ9 CBS domain containing protein n=2 Tax=Verrucomicrobia
           RepID=B4CWQ9_9BACT
          Length = 250

 Score =  153 bits (386), Expect = 7e-36,   Method: Compositional matrix adjust.
 Identities = 80/242 (33%), Positives = 136/242 (56%), Gaps = 3/242 (1%)

Query: 39  ALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIES 98
            ++  S + + +    +++L   +D+ D+ VRDI  PR +++ L    T +E +   +ES
Sbjct: 3   VILSQSAEQEEVTPLGKEILINALDMRDRVVRDITTPRGKVVFLNTEDTFEENIQRALES 62

Query: 99  AHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEF 158
            H+RFP+     DH  G++  KD+L  + S      +  + R  + VPE   ++++L  F
Sbjct: 63  RHTRFPLCEGHLDHTIGLVHIKDVLKLLNSQNR--DLHTIKRDLLPVPEMMSLEKLLTFF 120

Query: 159 RSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA 218
             +  H+A+V+DEFGG +G+VT++++LE +VGEI+DE+D E   +FR+L+   +TV    
Sbjct: 121 LGKHAHLALVVDEFGGTTGIVTLDNVLEELVGEIQDEFDAEKP-EFRRLNADEFTVEGSL 179

Query: 219 SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVH 278
            + +  +  G      +V TIGG V    GHLP +GE + I+ Y   +   D RR+ QVH
Sbjct: 180 GLYELQDLAGLELDSPDVSTIGGYVTHLLGHLPKQGEQVKIEDYDVTITQTDGRRVGQVH 239

Query: 279 VK 280
            K
Sbjct: 240 FK 241


>UniRef50_D2NT77 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NT77_9MICC
          Length = 488

 Score =  153 bits (386), Expect = 7e-36,   Method: Compositional matrix adjust.
 Identities = 88/262 (33%), Positives = 148/262 (56%), Gaps = 11/262 (4%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + +EL   +  +   + I++D   M++ V ++ D R+R +M+PR+ M+T  R+  L E L
Sbjct: 169 DEEELREFLDRASDAETIEDDEAQMVQSVFEMDDTRIRSLMVPRTDMLTASRDTPLREAL 228

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF------SMDKVLRQAVVVP 146
            + + S +SR PVI +  D I G+L  KD +       EA       ++ +++R A   P
Sbjct: 229 SLFLRSGYSRMPVIGDSSDEILGVLYLKDAMRAFILHGEAPEGTALPTVVELMRPARFEP 288

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           ESKR   +L+E + +  H+AI++DE+GG +GL+T+ED++E +VG+I DEYD E   ++  
Sbjct: 289 ESKRAMDLLREMQRESTHVAIIVDEYGGTAGLITLEDLIEELVGDISDEYDHERP-EYTL 347

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
               T+ + A   I++  E FG    DE+VDT+GGL+ +  G +P  G  I+IDG   + 
Sbjct: 348 NDDGTFRLSARLGIDELGEIFGRELDDEDVDTVGGLLAKHLGMVPIVGSEIEIDGIHIRA 407

Query: 267 AMADSRR----IIQVHVKIPDD 284
             +  RR    ++Q   + P D
Sbjct: 408 IGSSGRRHQVDMLQAWYEPPRD 429


>UniRef50_C5VQE4 CBS domain integral membrane protein n=9 Tax=Clostridiales
           RepID=C5VQE4_CLOBO
          Length = 429

 Score =  152 bits (385), Expect = 9e-36,   Method: Compositional matrix adjust.
 Identities = 85/270 (31%), Positives = 149/270 (55%), Gaps = 10/270 (3%)

Query: 19  FSLLLSQLFH--------GEPKNRDELLALIRD-SGQNDLIDEDTRDMLEGVMDIADQRV 69
           F+LL +++          G+P   +E L  I D S +  +++ + R M+  V +  D +V
Sbjct: 145 FTLLTNKIVRIFGGRADMGKPHITEEELKTIVDVSHEEGVLEVEERKMIYNVFEFGDSQV 204

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           +D+M+PR++MI++  + T DE ++++ +   SR PV  +  D+I G+L  K L+ F  + 
Sbjct: 205 KDVMVPRTEMISIDVDSTYDEVIEILKKEQFSRMPVYKDSTDNIIGVLHIKRLV-FFDNS 263

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            + F + K + +     E K    +  E R  R  M IV+DE+GG +G+VT+ED++E IV
Sbjct: 264 KDKFDIYKYMIKPYFTYEYKPTTELFDEMRKNRVAMTIVLDEYGGTAGMVTMEDLVEEIV 323

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G+IEDEYD E + + + +    + V+    I++ NE   T    E+ D+IGG V+   G 
Sbjct: 324 GDIEDEYDNEQNDEIKLIKEDEYIVKGSTKIDEVNEMLKTSIESEDFDSIGGFVIGEIGR 383

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHV 279
            P +GE I+    +F +   D+ RI ++ +
Sbjct: 384 FPKKGEVIEFGNIKFIIEEIDNNRIKKLKI 413


>UniRef50_C5PXG9 TlyC family hemolysin n=5 Tax=Sphingobacteriales RepID=C5PXG9_9SPHI
          Length = 437

 Score =  152 bits (384), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 79/239 (33%), Positives = 144/239 (60%), Gaps = 4/239 (1%)

Query: 38  LALIRDSG-QNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           L  + D G ++  +D    ++++ V D  ++ V++IM+PR++++ + ++ T DE ++ + 
Sbjct: 184 LQYLLDKGKESGALDFSEHELIKNVFDFNERIVKNIMVPRTKIVAIDKDATADEFINTVT 243

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLK 156
           E  +SR P+  ++ D I GI+  KD+LP +    E   +  ++R+   +PE+K+++ ++ 
Sbjct: 244 EEGYSRIPIYDDNIDQIVGIVHTKDILPIIVKGKEVV-LKNIMRKPYFIPETKKINDLMA 302

Query: 157 EFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRA 216
           EF+ +R  +AIV+DEFGG +G+VT+EDI+E +VGEI+DEYDEE  +   ++S   + + A
Sbjct: 303 EFQLKRIQIAIVLDEFGGTAGMVTLEDIVEELVGEIQDEYDEETPV-VERISETEYMIDA 361

Query: 217 LASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
            AS+ D NE       +  + DT+ GLV   F  +P  GE  ++ GY F +     + I
Sbjct: 362 GASVHDVNEYLPLELPESSDYDTMAGLVSDLFDKIPEVGEYKELYGYTFTIMKKTQQNI 420


>UniRef50_A9IMV8 Hemolysin n=5 Tax=Bartonella RepID=A9IMV8_BART1
          Length = 341

 Score =  152 bits (384), Expect = 1e-35,   Method: Compositional matrix adjust.
 Identities = 94/280 (33%), Positives = 153/280 (54%), Gaps = 30/280 (10%)

Query: 34  RDELLALIRDSGQND--LIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
           RD+L   +  + + D  L   + R ML  ++ + + RV D+MIPRS++  L+ N +L E 
Sbjct: 52  RDDLTVALATNNEKDTALFSPEERTMLHNILRLREARVDDVMIPRSEIEALEINTSLGEA 111

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM------------RSDAEAFSMDKV- 138
           L    +  HSR PV +E  D   G++  +D+L +M            +SD    +   + 
Sbjct: 112 LKCFAKIGHSRIPVYAETLDDPRGMIHIRDILNYMTRFIINPTKTEQKSDLLQLNHTDLH 171

Query: 139 --------LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
                   +R  + VP S    ++L   ++ R  MA+VIDE GG  GLV++EDI+EL+VG
Sbjct: 172 TPIGELDLIRTVLFVPSSMLASKLLTRMQTTRTQMALVIDEHGGTDGLVSMEDIVELVVG 231

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF----SDEEVDTIGGLVMQA 246
           +IEDE+D  D+   R+   + W V A   +ED  +A G  F      +EVDTIGGL++  
Sbjct: 232 DIEDEHDHVDNAIVRE-HNNKWLVDARTELEDVEKALGPDFIVGEYGDEVDTIGGLIVSI 290

Query: 247 FGHLPARGETID-IDGYQFKVAMADSRRIIQVHV-KIPDD 284
              +P +GE ++ + GY+F++  AD RRI ++ + +IP++
Sbjct: 291 LDRIPEKGEVVEAVPGYKFRILEADKRRIKRLRIFRIPEN 330


>UniRef50_C9L5N7 Hemolysin-related protein n=1 Tax=Blautia hansenii DSM 20583
           RepID=C9L5N7_RUMHA
          Length = 463

 Score =  152 bits (383), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 87/280 (31%), Positives = 164/280 (58%), Gaps = 16/280 (5%)

Query: 19  FSLLLSQLFHGEPKNRD------ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
            S ++ +LF  +P  ++      E+++++ D+ +  +I+E+  +M++ +M+ ++   +DI
Sbjct: 171 LSNVVVRLFGVDPHKQEDDVTEEEIISMVDDAHEQGVIEENEAEMIQNIMEFSETEAQDI 230

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAE 131
           M  R  +  ++ N  L + L  ++++++SR+PV  ED D+I GIL  KD++      + E
Sbjct: 231 MTHRKNLHAIEENTLLKDALSYMLDNSNSRYPVYREDIDNIIGILHLKDVMRQITLPECE 290

Query: 132 AF---SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
                S+  ++R+AV VPE++ ++ + K  ++++ H+ +V+DE+G  SG+VT+EDILE I
Sbjct: 291 NLPIGSIPNLVREAVYVPETRSINDLFKRMQAKKIHLVVVVDEYGQTSGIVTMEDILEEI 350

Query: 189 VGEIEDEYDEEDDIDFRQLSR-HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           VG I DEYDE++  +F QL    +  +  L  +E  ++   + F +EE DT+ G +    
Sbjct: 351 VGNILDEYDEDE--NFIQLQNDQSLVMNGLTPLEQVDDVLNSDFDEEEFDTLNGYLTSLL 408

Query: 248 GHLPARGE--TIDIDGYQFKVAMADSRRIIQVHV-KIPDD 284
           GH+P   E   I   GY F +   ++  I +V V K+PD+
Sbjct: 409 GHVPNMAEDKEIKAKGYLFTILAVENNTIQKVRVEKLPDE 448


>UniRef50_D1AH17 Putative uncharacterized protein n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1AH17_SEBTE
          Length = 424

 Score =  152 bits (383), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 96/269 (35%), Positives = 153/269 (56%), Gaps = 12/269 (4%)

Query: 20  SLLLSQLFHGEPKNRDELLALIRDS-------GQND-LIDEDTRDMLEGVMDIADQRVRD 71
           S   S+LF+  P N D++  +  DS       G+ D  I+E+ ++M+  ++D  D   ++
Sbjct: 147 SKFFSRLFN-VPIN-DDMFLITEDSIKTYVVQGKEDGAIEEEEQEMIHSIIDFTDTSAKE 204

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           I+ PR+ +  L+ N+ LDE  D II+   SR P+  E  D++ GIL +KDLL F R+  +
Sbjct: 205 ILTPRTSIFALEGNKCLDEVWDSIIDQGFSRIPIYEEQIDNVVGILYSKDLLKFDRTRDK 264

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              + ++ R A  +P +K +  +L+EFR ++ HMAIVIDE+GG  GLVTIED+LE IVGE
Sbjct: 265 DVKVSELKRDAYFIPGTKTLIELLEEFREKQNHMAIVIDEYGGTLGLVTIEDLLEEIVGE 324

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHL 250
           I DEYD E++ +  Q+    + ++    IE  N+    +    +E DTI G V    G +
Sbjct: 325 IRDEYDFEEE-NINQIKDEVFDIKGDTEIETVNKELDINIPISDEYDTIAGYVHYELGKV 383

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHV 279
               + ++ + Y  +V   DS RI +V +
Sbjct: 384 AEVNDKVNGEDYVIRVLHLDSHRIDKVRI 412


>UniRef50_D1Y9A3 CBS domain protein n=3 Tax=Propionibacterium acnes
           RepID=D1Y9A3_PROAC
          Length = 432

 Score =  151 bits (382), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 82/248 (33%), Positives = 143/248 (57%), Gaps = 4/248 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   +  EL  ++  +  +DLI+   R+M+  V ++ D   +++M+PR+ ++ + R + L
Sbjct: 163 GPFTSEAELREMVDYAEASDLIEAGEREMIHSVFELGDTLTKEVMVPRTDVVYIPRTKNL 222

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF---SMDKVLRQAVVV 145
            + + + + S  SR PV+ E  D I G++  KDL   +  + + +   S++ ++R AV+ 
Sbjct: 223 RQAMSLALRSGFSRIPVVGEGFDDIRGVVYLKDLSQRVLDNPDGYATESVESIMRPAVLC 282

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFR 205
           P+SK VD++L+E +  R H+ IV+DEFGG +GLVTIEDI+E IVGEI DEYD E  +   
Sbjct: 283 PDSKPVDQVLREMQRDRNHLVIVVDEFGGTAGLVTIEDIVEEIVGEIVDEYDAEPTLT-E 341

Query: 206 QLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
           ++    + + +   ++D  E F     D++V+T+GGL+ +    +P  G  I  +G +  
Sbjct: 342 EIEDGVFRISSRLPVDDLGELFDLKVDDDDVETVGGLMAKELSVVPIPGSVIIWEGLEIT 401

Query: 266 VAMADSRR 273
              A  RR
Sbjct: 402 AEKATGRR 409


>UniRef50_C7LQH5 Putative uncharacterized protein n=1 Tax=Desulfomicrobium baculatum
           DSM 4028 RepID=C7LQH5_DESBD
          Length = 433

 Score =  151 bits (382), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 92/254 (36%), Positives = 133/254 (52%), Gaps = 7/254 (2%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           HG     DEL  LI  S  +  I+E+ R ++    D       + MIPRS++  L    T
Sbjct: 176 HGSVYTEDELRMLIDASYSSGQIEEEKRRLIRRAFDFNTTEACEAMIPRSEIAALPVTST 235

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVP 146
           LDE LD      +SR PV  ED D + G+L  +D+ PFM R     FSM  +L     VP
Sbjct: 236 LDEVLDAFRIHGYSRLPVYGEDLDDVVGVLFRQDMEPFMAREPGLVFSMTGLLHPPTFVP 295

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
             KR+  +LK+ ++ R H+  V+DE+GG+ GLVT+ED+LE IVGEI DEYDEE      Q
Sbjct: 296 SGKRLGSLLKQMQATRTHLIFVMDEYGGLEGLVTLEDVLEEIVGEINDEYDEEVR---SQ 352

Query: 207 LSR--HTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
           + R    + +  + ++ D N   G     DE   T+ G ++   G +   G+ + I    
Sbjct: 353 IVRDGTAFILDGMLAVRDLNRKLGLKLPEDEAYTTVAGFLLSEAGRVLEAGDEVPIKEGV 412

Query: 264 FKVAMADSRRIIQV 277
           FKV   + RRI+++
Sbjct: 413 FKVERLERRRIVRI 426


>UniRef50_D1C4W4 Putative uncharacterized protein n=1 Tax=Sphaerobacter thermophilus
           DSM 20745 RepID=D1C4W4_SPHTD
          Length = 445

 Score =  151 bits (382), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 84/241 (34%), Positives = 141/241 (58%), Gaps = 2/241 (0%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +EL  L+  S +   ++   ++M+  ++  AD     +M+PR++MI +  + TL E ++V
Sbjct: 188 EELEMLVEASARGGQLETSEQEMIHRLLTFADLDAGQVMVPRTEMIAVPVDITLPELIEV 247

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS-DAEAFSMDKVLRQAVVVPESKRVDR 153
           I     SR+PV  +  D I GI+ +KDL P + +   + FS+ ++ R+A+ VP+S  +D+
Sbjct: 248 IARERRSRYPVYDQTLDDIVGIVHSKDLFPILAAGKTDGFSIREITREAMTVPDSLPIDQ 307

Query: 154 MLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWT 213
           +L   + +R H+AIVIDE+GG +GL+T+ED++E IVGE++DE++  +  +   L   +  
Sbjct: 308 VLALMKQRRTHIAIVIDEYGGTAGLITMEDLVERIVGELQDEFERPEQ-EVEVLPDGSVR 366

Query: 214 VRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
           +  L  IE+ NE FG    D   DTIGG V    G  P  G+T+ +    F+V + D  R
Sbjct: 367 INGLMLIEEVNERFGLDIHDPNFDTIGGYVFGQLGRKPEVGDTVQVGDVTFRVDVLDGLR 426

Query: 274 I 274
           I
Sbjct: 427 I 427


>UniRef50_Q74EV6 CBS domain protein n=9 Tax=Desulfuromonadales RepID=Q74EV6_GEOSL
          Length = 444

 Score =  151 bits (382), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 94/287 (32%), Positives = 159/287 (55%), Gaps = 12/287 (4%)

Query: 11  TISNKKGFFSLLL----SQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           TISNK     + +    SQ F      R+E+  ++ +  +  +     ++ +  + D   
Sbjct: 158 TISNKAVLAMMGIKAEGSQAF----VTREEVQHIVAEGHEAGVFSATEQEYIRNIFDFTH 213

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
             VR++M+PR++M+ L   +   E +  ++++ +SR+PV  E  +++ G +  KDLL   
Sbjct: 214 TCVREVMVPRTRMVALDLARPRMELVREVLDNMYSRYPVYRESIENVVGFIHGKDLLGRT 273

Query: 127 RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
            +D E F+M+ ++R    VPE K+V+ +LKE +  R HMA+V+DE+GG+SGLVT ED+LE
Sbjct: 274 VTDPE-FAMESIVRPPFYVPEGKKVNELLKEMQRLRIHMALVVDEYGGISGLVTTEDLLE 332

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF-SDEEVDTIGGLVMQ 245
            +VGEIEDE+D  +    ++L   +  V AL SI D  +        D   DT+ GL++ 
Sbjct: 333 ELVGEIEDEHDIGEPGTVQRLPDGSLLVDALMSIGDLADLLKIKLEEDVPYDTLAGLILD 392

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
             G  P RGET++ D  +F +   + ++   V V+I ++ P    DE
Sbjct: 393 QLGRFPERGETVEWD--RFSLICEEVKQTAIVKVRIVENLPPQAGDE 437


>UniRef50_UPI000050F785 CBS domain-containing protein n=1 Tax=Brevibacterium linens BL2
           RepID=UPI000050F785
          Length = 417

 Score =  151 bits (381), Expect = 3e-35,   Method: Compositional matrix adjust.
 Identities = 86/256 (33%), Positives = 146/256 (57%), Gaps = 5/256 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G     D+L  L+  + ++D+I++  R+M++ V +++D    ++M+PR+ ++T+     L
Sbjct: 159 GPFVTSDQLRDLVERASESDVIEDGEREMIQSVFNLSDTSANEVMVPRTDLVTVNSGTPL 218

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDL---LPFMRSDAEAFSMDKVLRQAVVV 145
            + +++   S  SR PV  ED D I G+   KD+   L     DAE   +D + R  + V
Sbjct: 219 SKVMNLFFRSGFSRIPVSGEDLDDIRGVAYLKDVARRLHLHPEDAER-PVDILARGVLFV 277

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFR 205
           PE+K  D ++++ +    H+AI+IDE+GG +GLVTIEDI+E IVGEIEDEYD  DD +  
Sbjct: 278 PETKPADDLMEQMQVDSTHLAILIDEYGGTAGLVTIEDIVEEIVGEIEDEYDTSDD-ELV 336

Query: 206 QLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
           ++   ++ V    SI DF + F     +++V+++GGL+ +  G +P  G    I+G   +
Sbjct: 337 EVDDGSFVVSTRMSISDFADYFDVKIDEDDVNSVGGLLTKLIGRVPIDGSNARIEGLIIE 396

Query: 266 VAMADSRRIIQVHVKI 281
                 RR    HV++
Sbjct: 397 AMEGQGRRHRITHVRV 412


>UniRef50_C3J7T2 CBS domain pair n=4 Tax=Bacteria RepID=C3J7T2_9PORP
          Length = 435

 Score =  151 bits (381), Expect = 3e-35,   Method: Compositional matrix adjust.
 Identities = 82/237 (34%), Positives = 137/237 (57%), Gaps = 7/237 (2%)

Query: 51  DEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDK 110
           +E    ++  ++   D+   +IM+PR  M+ +         L  ++++ +SR PV    +
Sbjct: 195 NETQSKLIGEIIKFHDKTADEIMVPRVDMVMIDYQWDFATTLRFVLDAGYSRIPVFLGTQ 254

Query: 111 DHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVID 170
           D I+GIL  KD LP+  + ++ F    ++R A  VPE+K++D +L+EFRS+  H++IV+D
Sbjct: 255 DVIKGILYIKDCLPYTTAGSD-FDWHTLIRPANFVPENKKIDDLLEEFRSEHRHISIVVD 313

Query: 171 EFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH 230
           E+GG SGL+T+EDILE IVGEI DEYD ED++ + +L+  ++       I DF       
Sbjct: 314 EYGGTSGLITLEDILEEIVGEITDEYD-EDELPYTRLADGSFLFEGKTQINDFCRYLSLE 372

Query: 231 FS-----DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
            S      +E+DT+GG+ ++    LP  G  +   GY+F++   +  RI+Q+ V  P
Sbjct: 373 DSLFEPLTQEIDTLGGVFLELKQELPRVGAFVTYRGYRFEITKVEKHRIMQMRVIPP 429


>UniRef50_D2RIW5 CBS domain containing protein n=2 Tax=Acidaminococcus
           RepID=D2RIW5_ACIFE
          Length = 284

 Score =  151 bits (381), Expect = 3e-35,   Method: Compositional matrix adjust.
 Identities = 86/256 (33%), Positives = 151/256 (58%), Gaps = 7/256 (2%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   + D++  ++  S +   ID     +++ V D AD+  R++M+PR  M+ L  +  +
Sbjct: 21  GTSHSEDDIRKMVSASEKGGSIDPVESRLIDNVFDFADRVAREVMVPRQDMVCLFVDDPI 80

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE--AFSMDKVLRQAVVVP 146
           +E + VI ES H+R+P+  ED+DHI G++  ++   FM +D +   F +  ++R+  VVP
Sbjct: 81  EENMKVIRESGHTRYPLCEEDRDHILGMVHIRE---FMNADYKQPGFDLRSIMREIDVVP 137

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           ES  + ++L+  + +   MA V DE+GG +GLVT+ED+LE IVG+I+DE+D  D  +  +
Sbjct: 138 ESMSIAKILQLMQHKHVQMAAVADEYGGTAGLVTMEDLLEEIVGDIQDEHD-TDMPEINK 196

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
           +   ++    L  +++ +E  G  F D E DTIGG V    G  P  G++++ +G +F+V
Sbjct: 197 MPDGSYVFDGLVLLDEVSEIMGIQFDDPEEDTIGGYVFGLIGRQPVVGDSVEENGCKFEV 256

Query: 267 AMADSRRIIQVHVKIP 282
             +   R+++V V IP
Sbjct: 257 LDSTGFRVLRVRV-IP 271


>UniRef50_B8I559 Putative uncharacterized protein n=1 Tax=Clostridium cellulolyticum
           H10 RepID=B8I559_CLOCE
          Length = 434

 Score =  150 bits (380), Expect = 4e-35,   Method: Compositional matrix adjust.
 Identities = 84/264 (31%), Positives = 153/264 (57%), Gaps = 12/264 (4%)

Query: 25  QLFHGEPKNRD------ELLALIRDSGQNDLIDEDT-RDMLEGVMDIADQRVRDIMIPRS 77
           ++F G P   D      E + ++ + G+   + +DT ++M++ + +  ++ V +IM  R+
Sbjct: 166 KVFGGNPAGGDDEKVTEEEIRMMMEVGEERGVIQDTEKEMIDNIFEFDNKSVSEIMTHRT 225

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            ++ +  +  ++  L ++    ++R P+ +++ D+I GIL  KDLL + +S  + FS+ K
Sbjct: 226 NIVGIPVDSDINYVLYIMNRDKYTRVPIYNDNIDNIVGILHVKDLLEYTQSHNKDFSLKK 285

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
           ++R A  VPESKR D + KE +  + H+A+VIDE+GG +G+VTIED+LE IVG I DEYD
Sbjct: 286 IIRSAYFVPESKRTDELFKEMQKNKVHLAVVIDEYGGTAGIVTIEDLLEEIVGNIFDEYD 345

Query: 198 -EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE- 255
            E+ DI++  L  +T+       ++   E        ++ DT+GG +++  G +P   E 
Sbjct: 346 IEQKDIEY--LENNTYIFDGAIDLDKVEEVLDEDLPVDDFDTLGGFILKLLGRIPKVDEK 403

Query: 256 -TIDIDGYQFKVAMADSRRIIQVH 278
            T+  +   FKV   + +RI++V 
Sbjct: 404 PTVPYENIVFKVVKMEGKRIVKVQ 427


>UniRef50_A9HIL4 CBS domain containing protein n=11 Tax=Acetobacteraceae
           RepID=A9HIL4_GLUDA
          Length = 324

 Score =  150 bits (378), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 86/239 (35%), Positives = 139/239 (58%), Gaps = 6/239 (2%)

Query: 47  NDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVI 106
           N  +D   R ++  V+ +      D+M+PR+ ++ +  + +LDE L ++    HSR PV 
Sbjct: 77  NSELDRQERALIANVLRLRGITADDVMVPRADIVAMPVSLSLDEALALMRRENHSRMPVY 136

Query: 107 SEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMA 166
            E  D I G++  KDL+ ++   +E F+++ +LRQ ++V     V  +L + R +R H+A
Sbjct: 137 REQLDDIVGMIHVKDLIAYV-GTSEGFNVESLLRQPLMVAPQIPVLDLLLQMRQRRVHLA 195

Query: 167 IVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEA 226
           ++IDE+GG+ GLVTIED++E IVG+I DE+DE   +  ++    T+ V A   +E F   
Sbjct: 196 LIIDEYGGIDGLVTIEDLVETIVGDISDEHDEPTAVLIQERPDGTFDVDARLPVEQFESR 255

Query: 227 FGTHFSD----EEVDTIGGLVMQAFGHLPARGETIDID-GYQFKVAMADSRRIIQVHVK 280
            G   +D     E++T+GGLV    GH+P RGE +  D G  F+V  ADS  I +V V+
Sbjct: 256 LGPLLTDAEREAEIETVGGLVFYLAGHVPTRGEVLTHDSGLVFRVLDADSLHIRKVRVR 314


>UniRef50_A0M7C1 Gliding motility protein GldE n=23 Tax=Bacteroidetes
           RepID=A0M7C1_GRAFK
          Length = 440

 Score =  150 bits (378), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 80/241 (33%), Positives = 142/241 (58%), Gaps = 13/241 (5%)

Query: 51  DEDT----RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVI 106
           +EDT    + +L+G++   +   + +M PR  +  L    +  + +  IIE+ +SR PV 
Sbjct: 200 EEDTTREEQKILQGIVSFGNTDTKQVMRPRMDIFALNEESSYFDIIPDIIENGYSRIPVY 259

Query: 107 SEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMA 166
            E+ D++ GIL  KDLLP++  + + F    +LR+   VPE+K++D +L +F++++ H+A
Sbjct: 260 KENVDNVTGILYIKDLLPYL--NKKNFEWTSLLREPYFVPENKKLDDLLNDFKNKKNHLA 317

Query: 167 IVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEA 226
           IV+DE+GG SGL+++EDI+E IVG+I DE+D+ED I + +L  + +       ++DF + 
Sbjct: 318 IVVDEYGGTSGLISLEDIIEEIVGDISDEFDDEDLI-YSKLDENNFVFEGKTPLKDFYKI 376

Query: 227 FGTH----FSDE--EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
                   F D+  E DT+ G +++  G  P + + I    Y F + + D +RI Q+ + 
Sbjct: 377 AKIEDPMVFEDQKGEADTLAGFLLEISGGFPKKNDEITFLNYSFIIEVIDDKRIKQIKLS 436

Query: 281 I 281
           I
Sbjct: 437 I 437


>UniRef50_A3ZXV1 Hemolysin protein n=1 Tax=Blastopirellula marina DSM 3645
           RepID=A3ZXV1_9PLAN
          Length = 430

 Score =  150 bits (378), Expect = 7e-35,   Method: Compositional matrix adjust.
 Identities = 88/251 (35%), Positives = 148/251 (58%), Gaps = 2/251 (0%)

Query: 40  LIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA 99
           ++ +  +  L++ED R+M+E V+++ D  V D+M  RS++  L    + ++ +  + E+ 
Sbjct: 178 IVTEGLREGLLEEDAREMIESVIELGDIDVADVMTSRSEVDALPIETSWEDVVKFVHETG 237

Query: 100 HSRFPVISEDKDHIEGILMAKDLLP-FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEF 158
            +R P   E  D I G+L  KD+L   ++  A+  S+  + R+A +VP+S  +D +LK+F
Sbjct: 238 RTRIPAYHEGLDQIVGVLYVKDMLSELVKPAADRKSLRDLARKAAMVPKSMPIDELLKQF 297

Query: 159 RSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA 218
             +R HMAIVIDE+  V+GL+TIEDILE IVGEI DE+D+ ++ +  ++SR    V+  A
Sbjct: 298 LRERNHMAIVIDEYHAVAGLITIEDILEEIVGEIVDEHDQNEEEEIVRISRDQAEVQGRA 357

Query: 219 SIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQV 277
            I+D NE  G      ++ DT+ G+V+     +P  G+ I +D  +  V  AD RRI ++
Sbjct: 358 HIDDVNEELGLDLPVGDDYDTLAGMVISRLQKIPKTGDRIRVDDVEIVVIAADRRRIQKL 417

Query: 278 HVKIPDDSPQP 288
            +   D +  P
Sbjct: 418 QLTKLDPAESP 428


>UniRef50_Q01WS1 Putative uncharacterized protein n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01WS1_SOLUE
          Length = 446

 Score =  149 bits (376), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 88/263 (33%), Positives = 144/263 (54%), Gaps = 13/263 (4%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           HG     +EL  ++  S     + E   DM+  V+D+    VR+IMIPR+ ++++  + +
Sbjct: 178 HGNVHTSEELKLIVSSSRGLGYLPETQEDMIHRVLDLGALSVREIMIPRNDIVSISTDAS 237

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF-------MRSD--AEAFSMDKV 138
           LDE L  + E  HSR PV  +  + I G+L  KDLLP        +RS   +++F + ++
Sbjct: 238 LDEVLHTMNEQRHSRLPVYEKTPEKIVGLLHYKDLLPVWEERRLAIRSSRPSQSFRVSRL 297

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R  + VPE+K V  ML EFR  R HMA+++DEFG + G+VT+ED+LE IVG+IEDE+DE
Sbjct: 298 MRPLMFVPETKEVSAMLDEFRHGRSHMAMIVDEFGTIIGMVTVEDVLEQIVGQIEDEHDE 357

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF-SDEEVDTIGGLVMQAFGHLPARGETI 257
             +   RQ+      +     I D    +G     D   +T+ G ++   G +P     +
Sbjct: 358 RVE---RQVEADDVELDGTTRIRDLESEYGIEIPPDAGFETLAGFLLFKLGEIPRVESRV 414

Query: 258 DIDGYQFKVAMADSRRIIQVHVK 280
           + +G ++ V   +  RI +V ++
Sbjct: 415 EYEGRRYTVLEMERNRIARVRIE 437


>UniRef50_C6W3X5 Putative uncharacterized protein n=1 Tax=Dyadobacter fermentans DSM
           18053 RepID=C6W3X5_DYAFD
          Length = 430

 Score =  149 bits (376), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 88/256 (34%), Positives = 144/256 (56%), Gaps = 4/256 (1%)

Query: 28  HG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQ 86
           HG E  + DEL  L++    + +I+    D+++   D +++  R IMIPR Q++ +  N 
Sbjct: 174 HGSEVHSSDELRYLVQQQKDSGMIEAADYDLIKNAFDFSERIARQIMIPRPQVVGIDVND 233

Query: 87  TLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVP 146
             +  L+ +IE  +SR PV  +  D + G+L  KDLL  MR   +   + +++R    V 
Sbjct: 234 FTEAKLEKVIEEGYSRMPVYEDTLDQVIGVLHLKDLLLKMRQGKD-IVLRELIRPIATVH 292

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
            SK +  +L+EF+  R  MA+++DE+GGV G+VT+EDILE +VGEI+DEYD E  I  + 
Sbjct: 293 GSKPIGALLREFQVSRQQMAVIVDEYGGVDGIVTMEDILEELVGEIQDEYDNEAPI-VKN 351

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
            S +T+TV+  ASI D N+      +   + +T+ G ++   G +PA GE +    Y+F 
Sbjct: 352 ESDNTYTVQGAASIADLNDKLPHDITRRPDYETLAGYLIWKCGRIPAVGEKVKTKHYEFT 411

Query: 266 VAMADSRRIIQVHVKI 281
           V       + QV + +
Sbjct: 412 VLKKQRSSVTQVKIAV 427


>UniRef50_Q1IKR3 CBS domain protein n=1 Tax=Candidatus Koribacter versatilis
           Ellin345 RepID=Q1IKR3_ACIBL
          Length = 422

 Score =  149 bits (375), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 86/260 (33%), Positives = 149/260 (57%), Gaps = 7/260 (2%)

Query: 30  EPKNRDELL-ALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           EP++  E + ALI    +  +++E  R +++ V++  D+ VR++M PR ++  +  + TL
Sbjct: 162 EPEHPSEAVDALIEAGTEEGILEESDRHLIQSVVEFGDKTVREVMTPRPRIFAVPTDWTL 221

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVV-VPE 147
           ++  D + +  +SR PV     D++ GI+ ++DLL    +DA    +  ++R+ ++ VPE
Sbjct: 222 EQLTDALRDQGYSRIPVFRGSIDNLVGIVFSRDLLQIADTDARTRKVGDLVREELMFVPE 281

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +KR   +L+E +     MA+VIDE+G V+GLVTIED++E IVGE+ D    ED+ D  + 
Sbjct: 282 TKRGSELLREMQRDNVRMAVVIDEYGSVAGLVTIEDLIEEIVGELRD----EDETDIVKE 337

Query: 208 SRHTWTVRALASIEDFNEAFGTHF-SDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
             HT+ V     ++  NE FG     D E  T+ GLV +  G +P  GE ++  G +F+V
Sbjct: 338 GEHTYVVPGSMDVDRLNELFGVRVDEDHESSTVAGLVSEIAGRIPQPGEVVENLGLRFEV 397

Query: 267 AMADSRRIIQVHVKIPDDSP 286
             +  RRI ++ +     +P
Sbjct: 398 LASTDRRIERLRISEATQTP 417


>UniRef50_C7IJK2 CBS domain containing protein n=5 Tax=Firmicutes RepID=C7IJK2_9CLOT
          Length = 377

 Score =  148 bits (374), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 87/264 (32%), Positives = 148/264 (56%), Gaps = 12/264 (4%)

Query: 25  QLFHGEPKNRD-------ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           +LF G P   D       E+  ++    +  +I +  ++M++ + +  ++ V +IM  R+
Sbjct: 109 KLFGGNPAGGDDEKVTEEEIRMMMEVGEERGVIQDSEKEMIDNIFEFDNKHVSEIMTHRT 168

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            +  +  +  L+  L V+    ++R PV SE+ D+I GIL  KDLL + +++A+ FS++K
Sbjct: 169 DIDGIPVDSDLEYVLYVMNRDKYTRVPVYSENLDNIVGILHVKDLLEYTQNNAKDFSLEK 228

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
           + R A  VPESKR D + KE +  + H+A+VIDE+GG +G+VTIED+LE IVG I DEYD
Sbjct: 229 ITRSAYFVPESKRTDELFKEMQKNKVHLAVVIDEYGGTAGIVTIEDLLEEIVGNIFDEYD 288

Query: 198 -EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE- 255
            E+ DI++  L   T+      S++   E        ++ DT+GG +++  G +P   E 
Sbjct: 289 IEQKDIEY--LENDTYVFDGAISLDRVEEVLDEELPVDDFDTLGGFILKLLGRIPKVDEK 346

Query: 256 -TIDIDGYQFKVAMADSRRIIQVH 278
             +  +   F+V   +  RI +V 
Sbjct: 347 PVVQYENIVFRVTEMEGMRIAKVQ 370


>UniRef50_B7RC07 CBS domain integral membrane protein n=5 Tax=Thermotogaceae
           RepID=B7RC07_9THEM
          Length = 455

 Score =  148 bits (374), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 76/251 (30%), Positives = 147/251 (58%), Gaps = 4/251 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           ++++++++  G+  +I+E+   +++   ++    V++IM PR  ++ ++ NQT+ + +++
Sbjct: 179 EDIVSIVQVGGEMGVIEEEEERIIKRAFEMKQIAVKEIMTPRVDIVAIEENQTVKDLIEL 238

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS----DAEAFSMDKVLRQAVVVPESKR 150
           + +  +SR PV  E  D+I GI  AKD+L  + +    + +A  +  ++R+A+ VPE+  
Sbjct: 239 VEDEGYSRIPVYKETIDNIVGICYAKDVLSILAAKDCEEVKAMKVKDIMREALYVPETMN 298

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH 210
           +D +LK  ++++ H+AIV+DE+GG +G+VT+EDI+E + G I DEYD ++    R++   
Sbjct: 299 IDELLKILKAKKIHIAIVVDEYGGTAGIVTLEDIIEELFGNIMDEYDYDEISGIRKIDER 358

Query: 211 TWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
           T+ V     I D        F + E +TI G +++ F  +P  GE   I    FK+    
Sbjct: 359 TFVVDGTTPINDIEMELRVQFPETEYETIAGYLLEHFKRIPNVGEEAVIGNLYFKILAVG 418

Query: 271 SRRIIQVHVKI 281
             RI +V +KI
Sbjct: 419 KNRIEKVMIKI 429


>UniRef50_A9F240 Conserved hypothetical membrane protein n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9F240_SORC5
          Length = 430

 Score =  148 bits (373), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 87/244 (35%), Positives = 141/244 (57%), Gaps = 10/244 (4%)

Query: 46  QNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPV 105
           ++ L   +  +M+  V++ AD   RD+M+PRS++  ++ +  L++ L+++ ES HSR+PV
Sbjct: 181 RSGLFGREPAEMIRNVLEFADLTARDVMVPRSKVEAIEISTPLEKVLEIVTESGHSRYPV 240

Query: 106 ISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQ-----AVVVPESKRVDRMLKEFRS 160
             +  D+I G+L AKDL   +    E    +  LR+     A  V ES+ +  +L+E +S
Sbjct: 241 YKDQTDNIAGLLYAKDLFKVLE---ERRLKNTTLREITRSPANFVAESQPLSSLLREMKS 297

Query: 161 QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD-IDFRQLSRHTWTVRALAS 219
           +R H+AIV+DEFGG+SG+VT+ED+LE IVG+I DE+DE DD    + L        A  S
Sbjct: 298 RRQHLAIVVDEFGGMSGIVTLEDVLEEIVGDIRDEHDETDDGAAIQDLGDGRLVADAAVS 357

Query: 220 IEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVH 278
           + D +   G     E + D++GG++ Q  G +P  G  +   G +F V  +D R I +V 
Sbjct: 358 MSDLSAYLGAELDREGKYDSLGGMLTQHVGKVPEVGTAVSKFGLRFIVRDSDERHIGKVE 417

Query: 279 VKIP 282
           +  P
Sbjct: 418 IVRP 421


>UniRef50_Q2FTJ8 Putative uncharacterized protein n=4 Tax=Methanomicrobiales
           RepID=Q2FTJ8_METHJ
          Length = 429

 Score =  148 bits (373), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 85/251 (33%), Positives = 149/251 (59%), Gaps = 10/251 (3%)

Query: 43  DSGQND-LIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHS 101
           D GQ +  I++D ++ML  V + +D RVR++M PR  ++ L+   + DE L++   +  S
Sbjct: 174 DVGQEEGTIEKDEQEMLHSVFEFSDTRVREVMTPRIDVVMLEDTSSSDEALEIFKNTGFS 233

Query: 102 RFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQ 161
           R P+   + D I+GIL  KD +  +    E+  + ++L + + VPE+K +D +L+E R++
Sbjct: 234 RLPIWHGNIDTIKGILNVKDAIFSVLETHESIPIVELLSEPLFVPETKNIDDLLRELRAK 293

Query: 162 RYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIE 221
           + HMAIV+DE+G   G+VT+EDILE +VG+I DE+D E+  +  +++   ++V A   +E
Sbjct: 294 KTHMAIVLDEYGSFVGIVTVEDILEELVGDILDEFDTEEH-ELVRVAEDVYSVDARMWVE 352

Query: 222 DFNEAFGTHF-SDEEVDTIGGLVMQAFGHLPARGETIDI--DGYQFKVAMADSRRI---- 274
           D N+    H  + E  +TI GLV++  G++P  G+  D+  +G +  +     +RI    
Sbjct: 353 DLNKHLDLHLPTSETYETIAGLVIERLGNIPRIGDVCDLTEEGVRLVIIQMTGKRINRLK 412

Query: 275 -IQVHVKIPDD 284
            I++H   P D
Sbjct: 413 LIRIHPPEPSD 423


>UniRef50_D2RB94 CBS domain protein n=1 Tax=Gardnerella vaginalis 409-05
           RepID=D2RB94_GARVA
          Length = 499

 Score =  147 bits (372), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 80/229 (34%), Positives = 131/229 (57%), Gaps = 3/229 (1%)

Query: 47  NDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVI 106
           ND  D +  +M+  V+ ++D   R+IM+PR+ MI +K ++TL+  L +   S  SR PVI
Sbjct: 219 NDF-DPEVSEMMRNVLTLSDTLTREIMVPRTDMICVKSDETLENFLKLCSRSGFSRVPVI 277

Query: 107 SEDKDHIEGILMAKDLL--PFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYH 164
            +  D + G+   KD +        A + +++ + R  ++VPESK VD +  E +  R H
Sbjct: 278 GDSVDDLVGVAYLKDAVRATVFNPAASSRAVETISRDPMLVPESKPVDDLFHEMQRIRQH 337

Query: 165 MAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN 224
           +A+V+DE+GG++GLVTIED +E IVGE+EDE+D     D  ++    W + A  SI D  
Sbjct: 338 VAVVVDEYGGIAGLVTIEDAIEQIVGELEDEHDRTQHADPEEIRDGVWKMPARTSIADLE 397

Query: 225 EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
           + F  H  +++VDT+ GL+ +  G++P  G +    G +     +  RR
Sbjct: 398 DIFEVHIDEDDVDTVFGLLTKLIGNVPIVGSSAITRGLKLTAVDSAGRR 446


>UniRef50_C1TQS8 CBS domain-containing protein n=2 Tax=Synergistaceae
           RepID=C1TQS8_9BACT
          Length = 425

 Score =  147 bits (371), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 77/248 (31%), Positives = 139/248 (56%), Gaps = 1/248 (0%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
            R+E+  ++     +  ++E  R M+ G++   D +V ++M+PR  M  +  + T++E +
Sbjct: 167 TREEIEQVVTIGEASGALEESERRMIHGIISFEDTKVSEVMVPRIDMDVVDSDITIEELI 226

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
             + E  HSR P+  +  D I GIL  KDL+  + S      +  + R A+ VPE+ +V 
Sbjct: 227 PHLEEHGHSRIPIYEDSLDDIIGILYVKDLIGLLYSGKTEVKLASLKRDALFVPETMKVP 286

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +    +S+R HMA+V+DE+GG +G++T+ED+LE IVGEI+DEYD E      ++    +
Sbjct: 287 DLFNIMKSRRIHMAVVVDEYGGTAGIITLEDLLEEIVGEIQDEYDHELP-AIEEVEEGVY 345

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V+    +ED ++  G  F  E+V+++GGL+    G  P  G ++    ++F V      
Sbjct: 346 QVQGNMDLEDLSDFLGYPFESEDVESVGGLITDLSGDFPGTGSSVTYGPWEFTVLSLADH 405

Query: 273 RIIQVHVK 280
           R+++V ++
Sbjct: 406 RVMEVELR 413


>UniRef50_C2ECT1 Hemolysin n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2ECT1_9LACO
          Length = 453

 Score =  147 bits (371), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 87/256 (33%), Positives = 144/256 (56%), Gaps = 9/256 (3%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           ++L +I +   N  +D +  +M++GV+ + D+  R+IM+PR+    +         +D I
Sbjct: 178 DILDMIEEGRNNGELDTNEYEMIDGVISMHDKMAREIMVPRTDAFMVDVTNDNSRNIDSI 237

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAFSMDKVLRQAVVVPESKRVDRM 154
           +    SR PV  EDKD++ GI+  K L+   R+   +  ++ + +R A  VPE+  +D +
Sbjct: 238 LGMDFSRVPVYHEDKDNVVGIVHIKTLVKLARNFGFDHITIRQAMRPAFFVPETMTLDEL 297

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
           L + +  R  MAI++DE+GGV GLVT+ED+LE IVGEI+DE DE D + ++Q+S   + V
Sbjct: 298 LFQMQKTRNQMAILLDEYGGVVGLVTLEDLLEEIVGEIDDESDEPDQL-YQQISSDEFLV 356

Query: 215 RALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI-------DGYQFKVA 267
           +    I+DFN+ FGT     ++DTI G ++   G +P   E + +       D       
Sbjct: 357 QGKMPIDDFNDEFGTDLKINDIDTIAGFLIAKLGRIPDNDEVVSVTTESSEGDVVLTTAK 416

Query: 268 MADSRRIIQVHVKIPD 283
           + D  RI +V V +PD
Sbjct: 417 IIDDARITEVKVTLPD 432


>UniRef50_B8JAD7 Putative uncharacterized protein n=4 Tax=Anaeromyxobacter
           RepID=B8JAD7_ANAD2
          Length = 464

 Score =  147 bits (370), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 84/273 (30%), Positives = 143/273 (52%), Gaps = 29/273 (10%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+  LI    +  ++DE   ++L  V++ AD+  +++MIPR++M+ + R    DE + +
Sbjct: 175 EEIEYLIEMGTREGVLDEVKEELLNSVLEFADRVAKEVMIPRTRMVAVDRAVEPDELVRI 234

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMR-SDAEAFSMDKVLRQAVVVPESKRVDR 153
           + E+ +SR PV     D++ GIL+ +D++  +R       ++D+ L+ A  VPE  ++ R
Sbjct: 235 VTENPYSRMPVYEGSIDNVVGILLVRDIIQELRHGPLRRIALDRYLKPAFFVPEQMKISR 294

Query: 154 MLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWT 213
           +LKE + +R H+A+V+DEFGG SGLVT+ED++E IVGEI+DE D E     + ++   W 
Sbjct: 295 LLKEMQRRRTHLAVVVDEFGGTSGLVTMEDVIEEIVGEIQDEADVESA-PVKAVAPGVWL 353

Query: 214 VRALASIEDFNEAFG--------------------------THFSDE-EVDTIGGLVMQA 246
             A   + D                                  F ++ + +T+GG V   
Sbjct: 354 ADAAIPLHDLQSFLNEQREEPAPRPAGDDAPEPEDGEPPPEIRFPEQGDYETLGGFVTAT 413

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
            G +P  G T+  DG  F V   D RR+ +V +
Sbjct: 414 AGRVPPVGATLAWDGLTFTVRAGDERRVTRVEI 446


>UniRef50_A0LG68 CBS domain containing protein n=1 Tax=Syntrophobacter fumaroxidans
           MPOB RepID=A0LG68_SYNFM
          Length = 276

 Score =  147 bits (370), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 79/248 (31%), Positives = 140/248 (56%), Gaps = 9/248 (3%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           E+  LI +  Q  LI ED  +M++G+    D   R+IM+PR+  +  +   T  + + +I
Sbjct: 18  EIQQLIDEGEQAGLISEDEGEMIQGIFSFRDTIAREIMVPRTDAVYARAETTTADVIQLI 77

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRML 155
           I+S HSR P+  +  D+I G L AKDLL +  SD     +  ++R    +PESK++  +L
Sbjct: 78  IQSGHSRIPIYQDSIDNIIGTLHAKDLLKYWGSDD--VDLRAIIRSPYFIPESKKISEVL 135

Query: 156 KEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH---TW 212
           ++ R  + HMAIV+DE+GG +G++T+EDI+E I+G++ DEYD     D + +  H   + 
Sbjct: 136 EDLRDNKSHMAIVVDEYGGTAGILTLEDIIEEIIGDVMDEYDA----DVKLIVEHDDGSI 191

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
           TV A   +E+  +       + + +++GG V+   G +P   E I  +  +  +  A +R
Sbjct: 192 TVHARLDVEELEDFLDVKLPEGKFESVGGFVISLVGRVPGVNERIVFENMEMVIEAASNR 251

Query: 273 RIIQVHVK 280
           +I ++ ++
Sbjct: 252 KIEKIRIR 259


>UniRef50_A0PYY8 Integral membrane protein with CBS domains n=15 Tax=Clostridiaceae
           RepID=A0PYY8_CLONN
          Length = 422

 Score =  147 bits (370), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 80/233 (34%), Positives = 133/233 (57%), Gaps = 2/233 (0%)

Query: 29  GEPKNRDELLALIRD-SGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           G+P   +E L  I D S +  +++ + R M+  V +  D +V+D+M+PR++M ++  + T
Sbjct: 166 GKPHITEEELKTIVDVSHEEGVLEVEERKMIYNVFEFGDSQVKDVMVPRTEMASVDIDST 225

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
            DE L+V+ +   SR PV  +  D+I GIL  K L+ F  +  E F + K + +     E
Sbjct: 226 YDEILEVLKKEQFSRIPVYKDSTDNIIGILHIKKLV-FFDNSKEKFDITKYMVKPYFTYE 284

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
            K    + +E R  R  M +V+DE+GG +G+VT+ED++E IVG+IEDEYD E + + + +
Sbjct: 285 YKPTTELFEEMRKDRVAMTVVLDEYGGTAGIVTMEDMVEEIVGDIEDEYDNEQNDEIKLI 344

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
               + V+    I++ NE  G     E+ D+IGG V+   G  P +GE ++ D
Sbjct: 345 KDDEYIVKGSTKIDEVNEMLGIDIESEDFDSIGGFVIGEVGRFPKKGEFVEYD 397


>UniRef50_C7NH44 CBS domain-containing protein n=3 Tax=Actinomycetales
           RepID=C7NH44_KYTSD
          Length = 495

 Score =  147 bits (370), Expect = 6e-34,   Method: Compositional matrix adjust.
 Identities = 87/272 (31%), Positives = 152/272 (55%), Gaps = 16/272 (5%)

Query: 9   SDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
            + ++  KGF          G  +N  E   ++  +G++ +I+ + R+M+  + ++ D  
Sbjct: 148 GNAVTPGKGFA--------EGPFENEAEFRDMVDLAGESSVIEAEEREMIHSIFELGDTT 199

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED-KDHIEGILMAKDLLPFMR 127
            R +M+PR+ M+ ++ ++ L + + + + S  SR  V+ E   D I G++  KD++  + 
Sbjct: 200 ARRVMVPRTDMVVIEGHKQLRKVMSLALRSGFSRILVVGEGGTDDILGVVHFKDVVRRVN 259

Query: 128 SDA---EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDI 184
           +D    E+ +  +V+R+A  VPESK VD++L+E +  + H+ +VIDE+GG +GL+TIEDI
Sbjct: 260 ADPAARESLTAAEVMREATFVPESKNVDQLLREMQVSQTHLVVVIDEYGGTAGLLTIEDI 319

Query: 185 LELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD---EEVDTIGG 241
           LE IVGEI DE+D E   +  QL    W V A   ++   + F   FS+   E+V+T+GG
Sbjct: 320 LEEIVGEITDEHDRE-TAESTQLEDGAWRVAASMDVDHLADLFEVSFSEEVTEDVETVGG 378

Query: 242 LVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
           L+ +    +P  G T D+ G +        RR
Sbjct: 379 LLAKLVDRVPIVGSTGDVAGIRLTAERLSGRR 410


>UniRef50_B0VIA5 CBS domain protein (Modular protein) n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VIA5_9BACT
          Length = 421

 Score =  146 bits (369), Expect = 7e-34,   Method: Compositional matrix adjust.
 Identities = 79/228 (34%), Positives = 134/228 (58%), Gaps = 5/228 (2%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
           + ML G+    +  +++I +PR ++  ++ N+ L+E   VII+S +SR PV     D I 
Sbjct: 192 KKMLVGLFRFKEAEIKEIYVPRVKITAIEENKDLEELKQVIIDSGYSRIPVYRGTIDEIV 251

Query: 115 GILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGG 174
           GI+  KDLL +     E  ++ +++R    V E+ +V  +L +F+ ++  +A+V+DE+GG
Sbjct: 252 GIIYVKDLLLY----PEKKTIKELMRPVWFVTENMKVQALLNQFKQKKLQIAVVVDEYGG 307

Query: 175 VSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE 234
            SG++++EDILE IVG+I DEYD+++  +  +   +T+ +    S+  FNE F T  S E
Sbjct: 308 TSGIISLEDILEEIVGDIRDEYDKDEIPELIKKDENTYIISGNFSVRQFNEDFSTEISVE 367

Query: 235 EVDTIGGLVMQAFGHLPARGETIDI-DGYQFKVAMADSRRIIQVHVKI 281
           + D I   ++  F ++PA G T    D  +F V  AD + I Q+ VKI
Sbjct: 368 DYDNIAEFLLAYFNNVPAIGATAKYDDKLEFTVLDADEKSIKQIQVKI 415


>UniRef50_C4GBW1 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
           DSM 14600 RepID=C4GBW1_9FIRM
          Length = 458

 Score =  146 bits (368), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 83/250 (33%), Positives = 133/250 (53%), Gaps = 3/250 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +EL  ++  S +  +I+ + R+ +  + D  D  VR++MIPR  +     N + D+ + V
Sbjct: 170 EELRTIVDVSQEAGVIEHEERNYIHNLFDFTDSNVREVMIPRIDVTVANVNWSYDKLISV 229

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
                 +R PV  E+ D I GI+  KDLL  +  D   FS+   LR A    E K    +
Sbjct: 230 FAGCMFTRLPVYDENSDSIVGIINMKDLL--LVKDKAHFSLRDYLRSAYFTFELKNTREL 287

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
            +E R     MAIV+DE+G  +G++++ED+LE +VGEI DEYD  ++ D  QL+   + V
Sbjct: 288 FEEMRQNSIAMAIVMDEYGAFAGIISLEDLLEELVGEIRDEYDSNEEDDIVQLNEREYLV 347

Query: 215 RALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET-IDIDGYQFKVAMADSRR 273
               ++ED        +  E+ DTIGG +   F H P +GET +D +G   KV      R
Sbjct: 348 VGSMNLEDLMSIIPLGYESEDYDTIGGYLTGEFDHFPNQGETYVDSNGAILKVEKVRKNR 407

Query: 274 IIQVHVKIPD 283
           I ++ +++P+
Sbjct: 408 ITKILIRLPE 417


>UniRef50_C8NIX4 Hemolysin n=3 Tax=Firmicutes RepID=C8NIX4_9LACT
          Length = 457

 Score =  145 bits (367), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 82/253 (32%), Positives = 146/253 (57%), Gaps = 4/253 (1%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E   R E+ +L+ +S  +  ID     M++GV+ +  +  R++M+PR+  + L  +  L 
Sbjct: 180 EKLTRSEMKSLLANSRNDGAIDISEFAMMQGVLSLDTKLAREVMVPRTDTLMLDVDDDLA 239

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAFSMDKVLRQAVVVPES 148
           E L+ I+  ++SR P+  EDKD + G++  KD+    R    +   +  +  + V VP +
Sbjct: 240 ENLETILNCSYSRLPLYEEDKDTVIGVIHVKDVFRAAREQGFDNIDLRALAHEPVFVPST 299

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             VD +L EFR  R H+A++ DE+GGV G+VT+ED++E IVG+IEDEYD E+  +  ++ 
Sbjct: 300 IFVDDLLVEFRKTRQHLAVLKDEYGGVEGIVTLEDLIEEIVGDIEDEYDIEEK-EVVEID 358

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI--DGYQFKV 266
            +   + A  S++ FN+ + T    +EVDT+ G +++  G+ P   E + +  +GY  + 
Sbjct: 359 ENNSEIDAGMSLDRFNQIYQTSLESDEVDTMAGAIIEKLGYFPDDEEVVKVRFEGYMLQP 418

Query: 267 AMADSRRIIQVHV 279
              ++ RI ++HV
Sbjct: 419 TEIENDRIRKIHV 431


>UniRef50_A9NGP1 Putative hemolysin-related protein n=2 Tax=Bacteria
           RepID=A9NGP1_ACHLI
          Length = 422

 Score =  145 bits (367), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 81/251 (32%), Positives = 144/251 (57%), Gaps = 9/251 (3%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + DEL+ ++ +  ++  IDE +  ++   ++ AD    DI  PR  ++ +      ++  
Sbjct: 164 SEDELIMIVDEVQESGAIDESSGTLIRSAIEFADLEAVDIYTPRIDVVAVSTAARHEDIF 223

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
            V  ES +SR PV  E+ DHI G++  KD   F     E F + ++++  + +P++K+V 
Sbjct: 224 KVFKESGYSRIPVYEENIDHIIGVMNYKD---FFMVLTEGFDIKEIIKDVLFIPKTKKVK 280

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI--DFRQLSRH 210
            +L E +  + HMA+VID++GG +G++T+EDILE +VG+I   +DE DDI    ++++ +
Sbjct: 281 DLLLELQQSKSHMAVVIDDYGGTAGILTLEDILEELVGDI---WDEHDDIIEAVKKMNDN 337

Query: 211 TWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
            + V   +SIEDF E  G+   +  V T+ G V++  G LP  G+T ++  Y F++   D
Sbjct: 338 QYLVLGNSSIEDFLEIIGSK-EEPNVLTVNGWVVEKLGTLPVEGKTYEVKPYTFEIVKMD 396

Query: 271 SRRIIQVHVKI 281
            +RI  V + I
Sbjct: 397 GKRIDLVQITI 407


>UniRef50_A9KQ60 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A9KQ60_CLOPH
          Length = 429

 Score =  145 bits (367), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 79/247 (31%), Positives = 134/247 (54%), Gaps = 1/247 (0%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +EL  ++  S +  +I+ + R M+  V+D  D   +D+M+PR  M     + +  + ++V
Sbjct: 169 NELRTIVDVSHEEGVIESEERKMITNVVDFGDSLAKDVMVPRINMAFASVDMSYSQLIEV 228

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
             E  +SR PV  E++D I GI+  KD+  F R D   F++   +R+     E K+   +
Sbjct: 229 FREEQYSRMPVYDENRDDIVGIINLKDVF-FFRGDYNEFNIRDYMREPYYTYEYKKTSEL 287

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
           L E + +   M IV+DE+G  +GL+T+ED+LE IVGEI DEYD +++    +L  + +  
Sbjct: 288 LSEMKRESLPMVIVLDEYGATAGLITMEDLLEEIVGEIRDEYDYDEEDVITKLGENEYLA 347

Query: 215 RALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
              A +++ NE  G     E+ D+I G ++    HLP + E I  +   + V   +  RI
Sbjct: 348 DGSAKLDEINEFIGLSLDSEDYDSIAGHIIHLLDHLPEQDEQITENNITYTVTKVEKNRI 407

Query: 275 IQVHVKI 281
            +VH+KI
Sbjct: 408 DKVHIKI 414


>UniRef50_B2V0W8 Putative membrane CBS domain protein n=14 Tax=Clostridiales
           RepID=B2V0W8_CLOBA
          Length = 417

 Score =  145 bits (367), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 84/261 (32%), Positives = 143/261 (54%), Gaps = 8/261 (3%)

Query: 25  QLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
           ++  G+PK        +EL  ++  S +  +++   ++M+  V D AD +V+D+M+ R  
Sbjct: 154 KILGGDPKASEPFITEEELKTMVGVSEEEGVLENVEKEMIFNVFDFADLQVKDVMVQRVD 213

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           +  L    T D+ L +I E   SR P+ ++  D I GIL  KDLL  + +  E F M+K 
Sbjct: 214 VSALDSEATYDDVLKLIKEEQFSRIPIYNQTIDDIIGILNVKDLL-MLENPRENFKMEKY 272

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R+     E K++  + KE + +R H+A+V+DE+GG  G++TIED++E IVG+IEDEYD+
Sbjct: 273 IREPYYTFEFKKIVELFKEMKKERNHIAVVLDEYGGTVGIITIEDLIEEIVGDIEDEYDD 332

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETID 258
            +      +  + + V     + D  +  G     +E D++GGL++   G +P   E I+
Sbjct: 333 ANT-SIEVIKDNEYIVDGSVRLHDIGDLIGIDMESDEFDSVGGLIIGELGRMPEEKEEIE 391

Query: 259 IDGYQFKVAMADSRRIIQVHV 279
            D  +F V   D  RI +V +
Sbjct: 392 CDSMKFIVENIDKNRIKKVRI 412


>UniRef50_C6PR79 CBS domain containing protein n=10 Tax=Clostridium
           RepID=C6PR79_9CLOT
          Length = 253

 Score =  145 bits (367), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 84/246 (34%), Positives = 143/246 (58%), Gaps = 2/246 (0%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+  L  +S ++ LID+     ++ + D +++ V+DIMIPR+ MI + +  + DE L++
Sbjct: 6   EEIKLLAEESYKHGLIDKTELTFVDNIFDFSEKTVKDIMIPRTDMICIFKEDSFDEILEM 65

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
            ++   +R+PV    KD + G +  KDL    + +    S++K+ R  + VPES  +  +
Sbjct: 66  TMKEQLTRYPVCENSKDEVIGFIHIKDLYK-QKIEGNEQSIEKITRNILSVPESTSISVL 124

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
            K+F+ ++ HMAI+IDE+GG SGLVTIEDILE IVGEI+DE+DE  + + + L+  ++ V
Sbjct: 125 FKKFKKEKEHMAIIIDEYGGTSGLVTIEDILEEIVGEIQDEFDEGLE-EIQLLNDGSYIV 183

Query: 215 RALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
                +ED  +        E +DTIGG +       P  G  I  + Y F ++  + +RI
Sbjct: 184 DGKVILEDIEDILNIPMITENIDTIGGWLYSKVELPPQVGNKITYENYDFIISKCNGKRI 243

Query: 275 IQVHVK 280
            ++ +K
Sbjct: 244 TKILIK 249


>UniRef50_Q1IYV3 CBS domain-containing protein DUF21 n=4 Tax=Bacteria
           RepID=Q1IYV3_DEIGD
          Length = 446

 Score =  145 bits (367), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 81/245 (33%), Positives = 137/245 (55%), Gaps = 3/245 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H    + +E+  ++  S Q  ++++D ++++  V D+++  VR++M PR++M+T++    
Sbjct: 176 HHTAYSEEEIRMIVSASSQEGVLEDDEKELVYNVFDLSETTVREVMTPRTEMVTVEATCP 235

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           L   L++  E  +SR PV  +  D++ G+    D+L ++    E    D V+     VPE
Sbjct: 236 LRRLLELNAEHGYSRVPVYQDSADNVVGVAHTSDVLRYLDRLDETLIAD-VMHPVFFVPE 294

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
             +++ +L + R ++ HMAIV+DEFGG SGLVT+ED LE IVGEI DE DEE+      L
Sbjct: 295 GMKINDLLAKMREKKSHMAIVVDEFGGTSGLVTLEDALEEIVGEIYDETDEEEQPLIEVL 354

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSD--EEVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
               + + A  ++ +  E  GT+  D   E DT+ G +   FG +P  G++    G+ F 
Sbjct: 355 GEGIYLMDASLTVGEVEERLGTNLEDGEGEYDTLSGFMTSHFGDIPEIGQSFVYGGWAFT 414

Query: 266 VAMAD 270
           V  AD
Sbjct: 415 VVDAD 419


>UniRef50_C0QRS4 CBS/transporter-associated domain protein n=5 Tax=Aquificales
           RepID=C0QRS4_PERMH
          Length = 429

 Score =  145 bits (367), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 83/253 (32%), Positives = 146/253 (57%), Gaps = 4/253 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + D+L++++    +  +  E+ ++++E  + + +  V +IM PR  +  + +  T+ E L
Sbjct: 169 SEDDLISIVNIGTEKKIFTEEEKEIIEATLQLHETAVSEIMTPRRDIFAIPKGLTVREVL 228

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
           ++I E  +SR PV   + D+I GIL  KD++ F++ + +   +D+ LR+   VPE   + 
Sbjct: 229 ELIKEKDYSRIPVYEGNLDNIIGILYIKDII-FLKFEGKEEKIDRFLREPYFVPEFTPLL 287

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            ++K+F  ++ HMAIV+DE G V GLVT +DILE IVG+I +EY+ E+    +Q+S + W
Sbjct: 288 NLMKKFEEKKNHMAIVVDEHGTVVGLVTFQDILEFIVGDIPEEYEPEEPF-IKQISMNKW 346

Query: 213 TVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
            V     +E   E  G    D+ E DT+GG ++      P  GE    + Y+F++   +S
Sbjct: 347 EVSGKIEVEILEEVVGIKLPDDYEFDTVGGFILDVLKRFPEEGEEFVYENYKFRILKMES 406

Query: 272 RRIIQVHV-KIPD 283
            RII V + K+P+
Sbjct: 407 NRIISVLIEKLPE 419


>UniRef50_C6J8N4 Putative uncharacterized protein n=1 Tax=Ruminococcus sp.
           5_1_39BFAA RepID=C6J8N4_9FIRM
          Length = 459

 Score =  145 bits (366), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 81/254 (31%), Positives = 144/254 (56%), Gaps = 9/254 (3%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+++++ ++ +  +I E+  +M++ ++   +    DIM  R  ++       L   +D 
Sbjct: 200 EEIISIVDEAHEQGVIQENEAEMIQNIISFNETEAHDIMTHRKNVVAFDEEILLKNMIDT 259

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA-FS----MDKVLRQAVVVPESK 149
           ++E  +SR+PV  E+ D+I+GI+  KD L FM  +  A F     +  ++RQA ++PE++
Sbjct: 260 MLEEGNSRYPVYEENIDNIKGIVHYKDALKFMTQNPWAKFKPLKELPGIIRQASLIPETR 319

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            +  +    ++++ HMAIV+DE+G  +G+VT+EDILE IVG+I DEYD ED+I  R    
Sbjct: 320 GIGDLFHTMQARKIHMAIVVDEYGQTAGIVTMEDILEEIVGDILDEYD-EDEITIRAQKD 378

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA---RGETIDIDGYQFKV 266
           ++  +  LA +ED  E     F D E +T+ G +    GH+PA      +I   GY F +
Sbjct: 379 NSLIIDGLAYLEDVEEELDADFGDTEFETLNGYLTNILGHIPADKDVNTSIKAIGYCFTI 438

Query: 267 AMADSRRIIQVHVK 280
               ++ I +V V+
Sbjct: 439 LSIGNKTIGKVKVE 452


>UniRef50_C1F7E2 CBS/transporter domain protein n=1 Tax=Acidobacterium capsulatum
           ATCC 51196 RepID=C1F7E2_ACIC5
          Length = 425

 Score =  145 bits (366), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 88/265 (33%), Positives = 149/265 (56%), Gaps = 7/265 (2%)

Query: 28  HGEPKNRDE---LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKR 84
           H E +  DE   + ALI    +  +++E  R+++   ++  D+ VR++M PR Q+  +  
Sbjct: 159 HTEARAEDESEAVEALIEAGEEEGILEESDRELIRSAVEFGDKVVREVMTPRPQLFAVPG 218

Query: 85  NQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVV 144
           + TL++  +++ E+ +SR PV     DHI GI+ A DLL     DA   ++  + R A  
Sbjct: 219 SLTLEQFTEMLRENPYSRVPVYEGSVDHITGIIFAHDLLQITDEDARTRTVASLQRPASF 278

Query: 145 VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF 204
           VPESK+V+ +L+E + ++ HM +VIDE+GGV+GLVTIED+LE IVG I DE+++ D    
Sbjct: 279 VPESKKVNALLREMQMEKQHMRLVIDEYGGVAGLVTIEDLLEEIVGSITDEHEDHDLAQV 338

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHF---SDEEVDTIGGLVMQAFGHLPARGETIDIDG 261
            +    +  V     I    E          D +  T+ GLV +  G +P  GE ++  G
Sbjct: 339 VREPSGSLIVPGTLEISTLEELLHEEVEIPQDMDATTVAGLVSELAGRIPMAGEVVEQLG 398

Query: 262 YQFKVAMADSRRIIQVHV-KIPDDS 285
            +F++  +  RRI ++ + ++P+D+
Sbjct: 399 MRFEILASTDRRIERMRIARLPEDT 423


>UniRef50_C6HVJ5 Putative uncharacterized protein n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HVJ5_9BACT
          Length = 460

 Score =  145 bits (366), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 86/252 (34%), Positives = 140/252 (55%), Gaps = 12/252 (4%)

Query: 47  NDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVI 106
           + +I+   +D+++ V    D  VR++M+PR +M+TL+   TL E + +  E+ +SR+PV+
Sbjct: 197 HGIINRTEQDLIQSVFKFTDISVREVMVPRVRMVTLRTGMTLSEIIGIFSENRYSRYPVL 256

Query: 107 SEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMA 166
             + + + GIL  KDL+  + +    F +DKVL     VPES +V  +LKE + +R  MA
Sbjct: 257 RAEGEEVAGILYYKDLVELLNAPG-TFRIDKVLHTPYFVPESMKVPYVLKEMQKRRTQMA 315

Query: 167 IVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEA 226
           +V+DE+G + GLVT+ED+LE IVGEIEDE DE       +L   ++ V A  SI D +E 
Sbjct: 316 LVLDEYGALDGLVTMEDLLEEIVGEIEDESDEVAK-PVERLRDGSYLVDASLSIRDLSED 374

Query: 227 FGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI---- 281
           +     + E+ +T+ G V+     +P  GE       +  V   D +R+ +V ++     
Sbjct: 375 YRIPIPEGEDYETLAGFVLSQLQTIPRGGEFFFSKNMKVTVVEVDRQRVSRVRIEFLDAP 434

Query: 282 -----PDDSPQP 288
                PD S +P
Sbjct: 435 ASSGTPDTSGKP 446


>UniRef50_C8VVX2 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C8VVX2_DESAS
          Length = 446

 Score =  145 bits (365), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 85/258 (32%), Positives = 146/258 (56%), Gaps = 6/258 (2%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H    +  EL  L+ +S ++  +D+D   +L+ V +   +  R+I++PR +++ L R +T
Sbjct: 185 HEASHSEKELQMLVSESYKSGHLDKDEWRLLQNVFEFEKRIAREILVPRPEVVFLDRRKT 244

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           L + +++  +S H+RFP+   D D++ G++  KDL        +  S++ V R  ++VPE
Sbjct: 245 LQQNIEIARQSEHTRFPLCDGDNDNVVGLIHIKDLFKL----KDETSINDVKRNIMMVPE 300

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
              +DR+LK+F+  R  MA+V+DE+GG SG+VT+ED+LE +VGEI DE+D E      + 
Sbjct: 301 GIPLDRLLKQFQQCRQQMALVVDEYGGTSGIVTMEDVLEKLVGEIHDEFDNEIPKIIPE- 359

Query: 208 SRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
              T+ V     +E+  E F    + D E DTIGG V    G  P  G+ +++  ++ +V
Sbjct: 360 KEGTFLVEGRLLLEEAKEMFHLPVTEDTEYDTIGGYVFGELGKRPKVGDIVELPNHRLEV 419

Query: 267 AMADSRRIIQVHVKIPDD 284
                 RI Q+ + I D+
Sbjct: 420 TRIQGLRIQQIRLNILDN 437


>UniRef50_A6DQ65 CBS:Transporter-associated region n=1 Tax=Lentisphaera araneosa
           HTCC2155 RepID=A6DQ65_9BACT
          Length = 418

 Score =  145 bits (365), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 82/230 (35%), Positives = 132/230 (57%), Gaps = 4/230 (1%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           M++GV ++ D  +R++M PR+ +  +++   L+E   + I S +SR PV  E  D I G+
Sbjct: 189 MIKGVFNLDDTSIREVMTPRTSITGVEKETPLEEIKKLFISSGYSRLPVYDEKPDQIIGL 248

Query: 117 LMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           + AKD L +  S      ++ +LR    V E++ +D  L  FR ++ H+AIV DEFGG +
Sbjct: 249 VYAKDFLDY--SKICQSKLNDLLRPVEFVQETETLDLSLPNFRKKKIHLAIVQDEFGGTA 306

Query: 177 GLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWT-VRALASIEDFNEAFGTHFSDEE 235
           GLVT+ED+LE IVGEI DE+D E ++   Q+ R  +  +   A+I+D N+A  +   DEE
Sbjct: 307 GLVTMEDLLEEIVGEIHDEFDTE-EVSQIQIQRPGFAIIDPRATIDDINQALDSAIPDEE 365

Query: 236 VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            DTIG  +    G +P     +D + +   +  AD R II + +++   S
Sbjct: 366 YDTIGAYIFNLTGDIPTAKTEVDCEFFTATILEADERNIISLSLEVKAKS 415


>UniRef50_A8U4Z8 Hemolysin n=1 Tax=Carnobacterium sp. AT7 RepID=A8U4Z8_9LACT
          Length = 448

 Score =  144 bits (364), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 87/258 (33%), Positives = 143/258 (55%), Gaps = 12/258 (4%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ--MITLKRNQT 87
           E   RDE  A +  S     ID D   ML+G++ +  +  R+IM+PR+   MI  K    
Sbjct: 180 EKMTRDEFRAYLEHSQIAGAIDPDEFTMLKGILSMDTKMAREIMVPRTDTFMIDYKEGSA 239

Query: 88  LD--ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAFSMDKVLRQAVV 144
           ++  + LD+     +SR PV  EDKD I GI+  K+LL   R+   +   +  +L + + 
Sbjct: 240 VNIPQLLDI----PYSRVPVYLEDKDSIIGIVHVKNLLKASRTTKIDDIDLKDILNEPLY 295

Query: 145 VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF 204
           VPE+  +D +L E R  R  +A++ DE+GGV G+VT+ED+LE IVG+I+DEYDE  ++  
Sbjct: 296 VPETIHIDDLLYELRRTRNQLAVLNDEYGGVVGIVTLEDLLEEIVGDIDDEYDETYNM-I 354

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI--DGY 262
            ++S   + V     +  FNE FGT     +VD+I G  +  +G++P  G+  ++  + Y
Sbjct: 355 EKVSESIYLVDGSTQLSKFNEYFGTEIESNDVDSIAGYFITQYGNIPQPGDNANVEYENY 414

Query: 263 QFKVAMADSRRIIQVHVK 280
             K    +  R++ ++V+
Sbjct: 415 LLKSNKVEGSRLVSLYVE 432


>UniRef50_B8G6A7 Putative uncharacterized protein n=3 Tax=Chloroflexus
           RepID=B8G6A7_CHLAD
          Length = 441

 Score =  144 bits (364), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 84/250 (33%), Positives = 137/250 (54%), Gaps = 14/250 (5%)

Query: 39  ALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIES 98
           AL+R+  +   ++   +  ++ V   +D+ VR IM PR ++  ++ N+TL E +D ++ S
Sbjct: 182 ALVREGAETGEVEPQEQQFIDRVFRFSDRAVRHIMTPRHEVEMVEANRTLGEVIDELLAS 241

Query: 99  AHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEF 158
            +SRFPV  E  D I GI+  +DLL   R   E   + + +   + VPE+ R   +L  F
Sbjct: 242 GYSRFPVYEETPDQIVGIVHVRDLLLLYRKKGEQALVREAVSPPLYVPENSRASALLTTF 301

Query: 159 RSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE---------EDDIDFRQLSR 209
           R  R HMA+V+ E GG+ G+VT+ED+LE IVGEI+DEYD+         ED     + S 
Sbjct: 302 RRSRRHMALVVGELGGIEGVVTLEDVLEEIVGEIDDEYDDATPPPIVRREDGSYLVEGSL 361

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
               VRAL  +++  +     +     +T+ GLV+   GH+P  G+ +   G++F+V   
Sbjct: 362 PVDEVRALLEVDELPDEDTFRY-----ETLAGLVISLIGHIPTAGDVVRWSGWRFEVVDM 416

Query: 270 DSRRIIQVHV 279
           D  R+ +V +
Sbjct: 417 DGLRVDKVLI 426


>UniRef50_C4Z1L1 Putative hemolysin n=2 Tax=Bacteria RepID=C4Z1L1_EUBE2
          Length = 293

 Score =  144 bits (363), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 82/286 (28%), Positives = 161/286 (56%), Gaps = 13/286 (4%)

Query: 4   DNSHSSDTISNKKGFFSLLLSQLFHGEPKN--RDELLALIRDSGQNDLIDEDTRDMLEGV 61
           ++ H +D    K   FS L  +   G+      +E++ ++ +S +  +++E+  +M+  +
Sbjct: 2   NDGHPADGKEKK---FSSLFKRFGRGKRDEDVTEEIMDMVNESHEQGVLEENEAEMIGNI 58

Query: 62  MDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKD 121
            +  +++  D+M  R+ ++ L  + T+ E  D ++E  +SR+PV   D D+I G+L  +D
Sbjct: 59  FEFGEKQASDVMTHRNNIVALDNDITVKEAFDRVMEENYSRYPVYDGDIDNITGVLHIRD 118

Query: 122 LLP-FMRSDAEAFSMDKV----LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           LL  ++    ++  + +V    L Q   +PE++ +  + ++ +S + HMAIV+DE+G  +
Sbjct: 119 LLKIYVEESNQSRKLGEVGKEILFQPYCIPETRNISPLFRQMQSDKIHMAIVVDEYGQTA 178

Query: 177 GLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEV 236
           G++T+EDILE IVG I DEYD+E++      +  ++ +   A +ED     G  F  E++
Sbjct: 179 GIITMEDILEEIVGNILDEYDDEEE-QIVTDADGSYIIEGQADLEDVEARLGIEFECEDI 237

Query: 237 DTIGGLVMQAFGHLPARGETIDI--DGYQFKVAMADSRRIIQVHVK 280
           DT+ G ++   G +P  GE+ ++  +GY FK     +R I++V V+
Sbjct: 238 DTLSGFMIYKLGKIPDDGESFEVEYNGYIFKTLEVRNRMILKVKVE 283


>UniRef50_C6J7K3 Putative uncharacterized protein n=2 Tax=Bacillales
           RepID=C6J7K3_9BACL
          Length = 454

 Score =  144 bits (363), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 78/240 (32%), Positives = 143/240 (59%), Gaps = 3/240 (1%)

Query: 40  LIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA 99
           L+  S ++ +ID+D   +++ + D +D   R++M+PR+ M  L  N + ++ + ++  + 
Sbjct: 203 LMDQSAKSGVIDKDEMKLVDNIFDFSDMLAREVMLPRTDMDCLYTNLSWEDNMKIVANTK 262

Query: 100 HSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFR 159
           HSR+PV  EDKD I G +   DLL  +    +   +++++R  + VPES  + ++L+  +
Sbjct: 263 HSRYPVAVEDKDQIIGFVHITDLL--LPDSEKPLRLEEMVRPILNVPESMEISQVLRLMQ 320

Query: 160 SQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALAS 219
            +   + +V+DE+GG +GL+T E+ILE IVG++ DE+++E   D  +++   ++V     
Sbjct: 321 KKHSQVTLVVDEYGGTAGLLTAEEILEEIVGDLHDEFEDERP-DIEKITDDVYSVDGRLL 379

Query: 220 IEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           IE+ NE  G+   DEEVD+IGG + +     PA+G+   +D + F+V  A   RI +V V
Sbjct: 380 IEEVNELVGSDIEDEEVDSIGGWLFKELEGTPAKGKRKQVDRFLFEVEEASRLRITRVKV 439


>UniRef50_A5UY55 Putative uncharacterized protein n=3 Tax=Chloroflexi (class)
           RepID=A5UY55_ROSS1
          Length = 479

 Score =  144 bits (362), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 88/267 (32%), Positives = 151/267 (56%), Gaps = 10/267 (3%)

Query: 31  PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDE 90
           P   D+++AL+R+   +  + +  + ++  V   +D+ VR +M PR+Q+  L  +  ++E
Sbjct: 194 PVTEDDIMALVREGAADGTVADAEQTVIHNVFKFSDRTVRSLMTPRTQITALDVDTPIEE 253

Query: 91  CLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKR 150
            L +  ES +SR PV     DH+ GIL  KDLL F     E  ++ ++LR  + V ES+R
Sbjct: 254 ALRIATESGYSRIPVYEGSLDHVIGILYVKDLLAFW-GQCEPPNLRELLRPPMYVIESQR 312

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH 210
             +  ++ +  R  +AIV+DE+G V+G++TIED+LE +VG+I DEYD+E D    +    
Sbjct: 313 AAQAFQQLKQNRNALAIVLDEYGQVAGVITIEDMLEELVGDISDEYDDETDESIVRRDDG 372

Query: 211 TWTVRALASIEDFNEAFGTHFSDEEV-----DTIGGLVMQAFGHLPARGETIDIDGYQFK 265
           ++ V  L    D  E      +D+ V     +T+ G ++   G +PA G+++  +GY F+
Sbjct: 373 SYLVDGLTPFADLRERLKLPPADDLVREHGFETLAGFLLALLGRIPAVGDSVKWEGYSFE 432

Query: 266 VAMADSRRIIQVHVKIPDDSPQPKLDE 292
           +   D RRI +V V +P   P+P +D+
Sbjct: 433 IVDMDGRRIDKVLV-VP---PRPAVDQ 455


>UniRef50_B9KAC3 Hemolysin-related protein n=1 Tax=Thermotoga neapolitana DSM 4359
           RepID=B9KAC3_THENN
          Length = 466

 Score =  144 bits (362), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 81/266 (30%), Positives = 149/266 (56%), Gaps = 10/266 (3%)

Query: 26  LFHGEPKNRD------ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQM 79
           L HG+  + D      +++++++  G+  +I+++   +++   ++    V++IM PR  +
Sbjct: 177 LRHGKKISEDLFITEEDIVSIVQVGGEMGVIEQEEERIVKRAFEMKQIAVKEIMTPRVDI 236

Query: 80  ITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKV 138
           + ++ NQT+ + +++I +  +SR PV  E  D+I G+  AKD+L  +   D E     KV
Sbjct: 237 VAIEENQTVRDLIELIEDEGYSRIPVYRETIDNIVGVCYAKDVLSILAEKDCEEVKNMKV 296

Query: 139 ---LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
              +R A+ VPE+  +D +LK  +S++ H+AIV+DE+GG +G+VT+EDI+E + G+I DE
Sbjct: 297 KDIMRDALYVPETMNIDELLKILKSKKIHIAIVVDEYGGTAGIVTLEDIIEELFGDIMDE 356

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
           YD ++    +++   T+ V     I D        F   E +TI G +++ F  +P  GE
Sbjct: 357 YDYDEVSGIKKIGEKTYIVDGSTPINDLEIELRIQFPQTEYETIAGYLLEHFKRIPNVGE 416

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKI 281
              I    FKV      RI ++ +K+
Sbjct: 417 EAVIGNLYFKVLAVGKNRIEKIMIKV 442


>UniRef50_A7BE68 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7BE68_9ACTO
          Length = 451

 Score =  144 bits (362), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 90/250 (36%), Positives = 143/250 (57%), Gaps = 7/250 (2%)

Query: 30  EPKNRDELLALIRD----SGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRN 85
           E + R EL++ +R+     G+ +  +E+ RDM+  V+D+    VR++M+PR+ M+T+  +
Sbjct: 174 EAQVRAELISDLREIVDEVGEPESFEEEDRDMVRSVLDLGHTLVREVMVPRTDMVTIDAD 233

Query: 86  QTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM--DKVLRQAV 143
                 L + + S  SR PV+ +D D I GIL  KDL+    +      M  ++++R A 
Sbjct: 234 TPAPSALRLFVRSGFSRVPVVGDDVDDIRGILYFKDLVSRWEATGGQLDMRAEQMMRPAE 293

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
              E K  D ML++ +++R+HMAIVIDE+GGV+GLVT+ED+LE +VGE+ DE+D    I+
Sbjct: 294 FAVEMKPADDMLRQMQAERFHMAIVIDEYGGVAGLVTLEDLLEEVVGELTDEHDRH-SIE 352

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
             ++    W V A   I +  E       DE+VD++GGL+ +A G +P  G T  + G  
Sbjct: 353 PEEVEPGVWRVPARYPISELGELLDREIEDEDVDSVGGLLAKAIGRVPLPGATGTLAGVI 412

Query: 264 FKVAMADSRR 273
                A  RR
Sbjct: 413 MTAEEARGRR 422


>UniRef50_D1AX34 CBS domain containing protein n=1 Tax=Streptobacillus moniliformis
           DSM 12112 RepID=D1AX34_STRM9
          Length = 404

 Score =  143 bits (361), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 80/243 (32%), Positives = 137/243 (56%), Gaps = 5/243 (2%)

Query: 41  IRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAH 100
           I +   N  ++++ ++M+  + +  D  V++IM PR+ +I     + LD   D IIE   
Sbjct: 165 IINCANNTEVEKEEKEMIHSIFNFTDTTVKEIMTPRTSIIAYDVEEILDNVWDDIIEHEF 224

Query: 101 SRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS 160
           SR P+ +E  D+I GI+  KDLL   +       +  ++++ V VPE+  +  ML+ FR 
Sbjct: 225 SRIPLYNESIDNICGIMYTKDLL---KCKNRNIKLKNLMKEMVYVPETVTLTYMLEFFRQ 281

Query: 161 QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASI 220
           ++ HMAI+IDE+GG  GL+TIED+LE IVGEI DEYD E++ +F+ +S++ + +     +
Sbjct: 282 KQQHMAIIIDEYGGTLGLITIEDLLEEIVGEIRDEYDIEEE-NFKSISKNVYELLGETLV 340

Query: 221 EDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           E+ NE +       EE DTI G +      +    + +  + Y  +V   D+++I +V +
Sbjct: 341 EEINEKYNLDIEISEEYDTISGYIQYKLERVAIEDDKVINNDYIIQVLKVDNKKIEKVKL 400

Query: 280 KIP 282
            I 
Sbjct: 401 IIK 403


>UniRef50_UPI000196CD6F hypothetical protein CATMIT_02806 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196CD6F
          Length = 427

 Score =  143 bits (361), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 79/250 (31%), Positives = 146/250 (58%), Gaps = 2/250 (0%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + ++L  ++  S +  +++++ ++M+  + D  D  +++IM PR  + T+  + T DE +
Sbjct: 167 SEEDLKTIVNVSHEEGVLEDEEKEMMHNIFDFGDTDIKEIMTPRIHVATVDYDATYDEVV 226

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
            V+ ES +SR PV+SE+ D I G+L  KD+L     D E F +   +R A  V E   + 
Sbjct: 227 AVLQESQYSRLPVLSEEGDEIVGVLHIKDIL-MKPVDHEHFQVKDYMRDAYFVYEFNHIS 285

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +    R +   +++V+DE+G ++G+VT+EDI+E IVGEI+DEYD+  + + +++S++ +
Sbjct: 286 DVFASMRKEHVSLSVVLDEYGVMAGIVTLEDIVEEIVGEIDDEYDDNSE-EVKKISKNVY 344

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V    +I++ N+  GT F+ EE ++IGGLV+      P   + + +D   F +   D  
Sbjct: 345 LVDGSLNIDEVNDRCGTEFASEEFESIGGLVLGQVNGSPNPHQKVYVDDCMFIIEKIDKN 404

Query: 273 RIIQVHVKIP 282
           RI  + + IP
Sbjct: 405 RIELLRLIIP 414


>UniRef50_C4LJQ9 Transporter of the HlyC/CorC family n=4 Tax=Corynebacterineae
           RepID=C4LJQ9_CORK4
          Length = 458

 Score =  143 bits (360), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 83/259 (32%), Positives = 143/259 (55%), Gaps = 15/259 (5%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
            G   N  EL  ++  + +  ++  + R M++ + D+A+ R R +M+PR+ M+ ++  ++
Sbjct: 160 QGPFTNEVELREMVDIASERGVVQVEERRMIQAIFDLANTRARQVMVPRTDMLWIESEKS 219

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS--MDKVLRQAVVV 145
             +   + + S HSR PV+ E+ D IEG++  KDL+     D    S  + +V+R A  V
Sbjct: 220 ARQATRLCVRSGHSRIPVVGENVDDIEGVVYLKDLVALSYDDPSKNSTPVKEVMRPAEFV 279

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE------ 199
           P+S  +D +L + ++   H+A+++DEFG ++GL++IEDILE IVGEI DEYDE+      
Sbjct: 280 PDSLPLDELLGDMQTSHDHIALLVDEFGAIAGLISIEDILEEIVGEISDEYDEDEVAPVE 339

Query: 200 --DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFGHLPARG 254
             DD  FR ++R  +++  L  + D        FS+E+   V+T+ GL+    G +P  G
Sbjct: 340 ELDDGSFRLVAR--FSLDELVELYDEKRGIDIEFSEEQLEDVETVAGLLAFELGRVPLPG 397

Query: 255 ETIDIDGYQFKVAMADSRR 273
             +   G  F+      RR
Sbjct: 398 AQVTTAGLTFRAEGGHDRR 416


>UniRef50_C0QYZ5 Hemolysin protein n=2 Tax=Brachyspira RepID=C0QYZ5_BRAHW
          Length = 444

 Score =  143 bits (360), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 82/250 (32%), Positives = 135/250 (54%), Gaps = 10/250 (4%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +++  +I    +  +I E T +ML GV+D  ++ V +IM PR  M+ ++    ++E + +
Sbjct: 164 EDITTIIHLGHKEGIIKEYTHEMLTGVIDFRNKTVEEIMTPRVDMVCIEAETDVNEIIKL 223

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAV-------VVPE 147
            +ES  SRFPV  E  DHI GI   + L  F         M+KV ++A+        VPE
Sbjct: 224 TVESGLSRFPVYEETVDHIIGIFHTRAL--FKEYVKGGGKMNKVKKKAIDYIMLPYFVPE 281

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +K +  +  + + ++  M I IDE+GG +GLVT+EDI+E I+G+IEDE D+++  D  + 
Sbjct: 282 TKTISSLFSDMQKKKLQMVITIDEYGGTAGLVTMEDIIEEIMGDIEDESDKKEA-DVIRF 340

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
                 +   ASIED N+        EE  TI G V+    H+P   E   + GY+ ++ 
Sbjct: 341 KGKRIIINGNASIEDVNKTLKLELEHEEYQTIAGYVIDMLDHIPETNERFILKGYRVRIM 400

Query: 268 MADSRRIIQV 277
             + RRI+++
Sbjct: 401 KVEDRRIVEM 410


>UniRef50_A3VQ34 CBS domain protein n=1 Tax=Parvularcula bermudensis HTCC2503
           RepID=A3VQ34_9PROT
          Length = 325

 Score =  143 bits (360), Expect = 7e-33,   Method: Compositional matrix adjust.
 Identities = 87/253 (34%), Positives = 137/253 (54%), Gaps = 12/253 (4%)

Query: 38  LALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIE 97
           L + + SG  D    D R+M+E ++    +RV D+ IPR+ ++ +     L + L     
Sbjct: 48  LVMAQQSGSGDEAVAD-REMVERIVAFNQKRVDDVAIPRADIVAVDIETNLSDLLQTFSS 106

Query: 98  SAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--------EAFSMDKVLRQAVVVPESK 149
           + HSR PV   D D   G++  KD +  + S+             +  +LR+ + VP S 
Sbjct: 107 ANHSRLPVYRGDLDDPLGMIHIKDFIGLLASNGLKDIEGEEGRHVVQSILRKLLYVPPSM 166

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            V  +L   ++ R HMA+VIDEFGG  GL+TIED++ELIVG+I DE+DE D     +++ 
Sbjct: 167 PVTELLLRMQASRVHMALVIDEFGGTDGLLTIEDLIELIVGDIRDEHDEGDTHAIHKIAD 226

Query: 210 HTWTVRALASIEDFNEAFGTHFS--DEEVDTIGGLVMQAFGHLPARGETID-IDGYQFKV 266
           + W   +   +E+  +  G  F+  D + DT+GGLV    G +P RGE I   +G +F++
Sbjct: 227 YRWEADSRVPLEELEDVIGAAFALDDHDADTMGGLVFSLAGRVPLRGEVITHPNGAEFEI 286

Query: 267 AMADSRRIIQVHV 279
             AD RRI +V +
Sbjct: 287 IDADHRRIRRVRI 299


>UniRef50_A7HZ85 CBS domain containing protein n=1 Tax=Parvibaculum lavamentivorans
           DS-1 RepID=A7HZ85_PARL1
          Length = 319

 Score =  143 bits (360), Expect = 9e-33,   Method: Compositional matrix adjust.
 Identities = 93/277 (33%), Positives = 150/277 (54%), Gaps = 12/277 (4%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRD-SGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           G+   LL    +G+   R+ L  +I +    +  +  + R ML  ++   + RV D+M+P
Sbjct: 27  GWLRALLGLNGNGDGSLRESLEEVIEEHEDMHRSLTAEERHMLVNILKFGELRVDDVMVP 86

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE---- 131
           R+ +I ++ +  L+ECL +   S+HSR P+  E  D   G++  KD+L ++    E    
Sbjct: 87  RADVIGVEESCPLEECLRLFHVSSHSRMPIYRETLDDPIGMVHLKDVLAWLAPQEEEAPP 146

Query: 132 --AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
             AFS+  + R  + VP S     +L + ++ R H+A+VIDE+GG  GLV+IED++E IV
Sbjct: 147 RPAFSLRSIRRNILFVPPSMPALDLLVKMQATRIHLALVIDEYGGTDGLVSIEDLVEEIV 206

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE----VDTIGGLVMQ 245
           GEIEDE+D ++     +    T    A   IED  +  G    +EE    VDT+ GLV  
Sbjct: 207 GEIEDEHDTDEGPALVRREDGTIDADARCPIEDLEDMIGLRLVEEEHEDDVDTLAGLVFS 266

Query: 246 AFGHLPARGETI-DIDGYQFKVAMADSRRIIQVHVKI 281
             G +P RGE +    G +F+V  AD+RRI ++ + +
Sbjct: 267 LLGRVPLRGELVRHPAGLEFEVKDADARRIKRMRIHL 303


>UniRef50_C0CHP0 Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica
           DSM 10507 RepID=C0CHP0_9FIRM
          Length = 460

 Score =  143 bits (360), Expect = 9e-33,   Method: Compositional matrix adjust.
 Identities = 76/264 (28%), Positives = 155/264 (58%), Gaps = 7/264 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+++++ ++ +  +I+E   +M++ ++  +++  +DIM PR  +  L    TL++ +++
Sbjct: 196 EEIISMVGEAHEQGVIEESEAEMIQNLISFSEKEAKDIMTPRMNITALDAQMTLNDAIEI 255

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS-----MDKVLRQAVVVPESK 149
           ++E  +SR+PV  ED D+I G+L  +D++P +     A       +  ++R  V +PE++
Sbjct: 256 MLEEGYSRYPVYVEDLDNILGVLNFRDVVPIITKSERAGERPLRELPGLIRSVVFIPETR 315

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            ++++L+  ++++ HM +V+DE+G   GLV +EDILE IVGEI DEYDEE+     QL +
Sbjct: 316 GINQILQGMQARKTHMVVVVDEYGQTEGLVAMEDILEEIVGEIHDEYDEEEANIQPQLDQ 375

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA-RGETIDIDGYQFKVAM 268
               +     +E+  E  G  F D+E++T+ G +     H+P  + + +  +GY+F++  
Sbjct: 376 SV-IIDGFTRLEELEEELGMEFGDQEMETLNGYLTYMLDHIPTIKDKEVIANGYRFEILS 434

Query: 269 ADSRRIIQVHVKIPDDSPQPKLDE 292
            ++  I +V  +    + Q  L+E
Sbjct: 435 VENNTIQKVKARKLPSAAQTPLEE 458


>UniRef50_C4G6D4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G6D4_ABIDE
          Length = 395

 Score =  142 bits (359), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 88/252 (34%), Positives = 142/252 (56%), Gaps = 2/252 (0%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +ELL  +  S +  +I+ + ++M+  V+D  D   +D+M+PR  M T+  + + DE L  
Sbjct: 131 NELLTYVEVSHEEGIIENEEKEMITNVVDFGDSLAKDVMVPRVDMYTISDDISYDELLLA 190

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
             E  +SR PV  E+ D+I GI+  KD+  F + D + F +  +LR A    E K+   +
Sbjct: 191 FEEDKYSRLPVYRENVDNIIGIVYLKDV-AFYKGDKKDFKLGSILRPANFTYEFKKTSEL 249

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
           L E R     M IV+DE+G   GL+T+ED+LE IVG+I DEYD ++  D  +L +  + V
Sbjct: 250 LIEMRKSSLSMCIVLDEYGSAVGLITLEDLLEEIVGDIRDEYDVDEVDDIVRLDQDEFMV 309

Query: 215 RALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
                ++DFN+ FGT +  ++ D+I G +++ F  LP +G+ I      F +   D RRI
Sbjct: 310 LGSTRLDDFNDFFGTEYISDDYDSIAGKLIELFERLPEKGDAITDGSLSFLIESIDHRRI 369

Query: 275 IQVHV-KIPDDS 285
            ++ V K+P  S
Sbjct: 370 EKIKVRKLPSTS 381


>UniRef50_Q5HR32 CBS domain protein n=18 Tax=Bacillales RepID=Q5HR32_STAEQ
          Length = 449

 Score =  142 bits (358), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 79/262 (30%), Positives = 151/262 (57%), Gaps = 4/262 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + +E+  +I +S     I++     ++ +    ++  +DIM+PR+QM+TL     +DE L
Sbjct: 182 SEEEIKIIINNSYNGGEINQTELAYMQNIFSFDERHAKDIMVPRTQMVTLNEPFNVDELL 241

Query: 93  DVIIESAHSRFPVISE-DKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           D I E   +R+P+  + DKDH++G +  K+ L    S  +   +   + +  ++ E+ R+
Sbjct: 242 DTIKEHQFTRYPITEDGDKDHVKGFINVKEFLTEYAS-GKPIKIANYIHELPMISETTRI 300

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
              L   + +  H++++IDE+GG +G++T+EDILE IVGEI DE+D+++  D  +L  HT
Sbjct: 301 SDALVRMQREHVHISLIIDEYGGTAGILTMEDILEEIVGEIRDEFDDDEVNDIVKLDDHT 360

Query: 212 WTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
           + +     ++D NE FG  F D E++DTIGG +     +L  + + +D +  ++ +   D
Sbjct: 361 YQINGRVLLDDLNEKFGIEFEDSEDIDTIGGWLQSQNTNL-QKDDFVDTEYDRWTITEID 419

Query: 271 SRRIIQVHVKIPDDSPQPKLDE 292
           + +II V++    +S +P ++E
Sbjct: 420 NHQIIWVNLNYEFNSGRPSVNE 441


>UniRef50_B5Y9X2 CBS domain protein n=1 Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y9X2_COPPD
          Length = 434

 Score =  142 bits (358), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 83/252 (32%), Positives = 150/252 (59%), Gaps = 9/252 (3%)

Query: 35  DELLALI-RDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLD 93
           +ELL ++ R   +   + E+  +M++ V++ +D  VR+IM PR  +  L +N  ++E L 
Sbjct: 176 EELLRIVERGRSEGQFLQEE-EEMIKSVLEFSDTTVREIMTPRLAVFWLDKNVGVNEALQ 234

Query: 94  VIIESAHSRFPVISEDKDHIEGILMAKDLLPF-MRSDAEAFSMDKVLRQAVVVPESKRVD 152
           ++++S +SR  +     D++ G++  KDL+   ++ D+E  S++ + R  + VPE++ ++
Sbjct: 235 LMLDSGYSRALLCDGSLDNVLGVIHIKDLMKLHVQGDSEG-SLESIKRDVLFVPETEMIN 293

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +  + R  R H+A+V+DE+G V+G+V++EDILE +VGEI DEYD+E++   R + +   
Sbjct: 294 EVFFQMRRLRNHLAVVVDEYGAVAGVVSLEDILEELVGEIRDEYDQEEE-PIRIVEKSEN 352

Query: 213 TVRAL----ASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
            V+A+     S+ D N+        EEVDTI G V+    H P  GE   +DG +F V  
Sbjct: 353 YVKAIVLGHVSLGDVNDVLDLDLEAEEVDTIAGFVLLQLQHFPEVGEKFRLDGTKFTVLS 412

Query: 269 ADSRRIIQVHVK 280
             ++RI +V ++
Sbjct: 413 VTNKRIDKVLIE 424


>UniRef50_B3DSC1 Hemolysin-like protein n=7 Tax=Bifidobacteriaceae
           RepID=B3DSC1_BIFLD
          Length = 477

 Score =  142 bits (357), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 81/230 (35%), Positives = 131/230 (56%), Gaps = 3/230 (1%)

Query: 46  QNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPV 105
            ND  D +  +ML  V+ ++D   R+IM+PR+ MI ++R+ TL   L +   S  SR PV
Sbjct: 209 SNDF-DPEVSEMLRNVLTLSDTLTREIMVPRTDMICMERDSTLSSALKLFSRSGFSRVPV 267

Query: 106 ISEDKDHIEGILMAKDLLPFMRSDAEAF--SMDKVLRQAVVVPESKRVDRMLKEFRSQRY 163
           I ED D + G+   KD +     +  A   +++ ++RQ ++VPESK VD +  E +  R 
Sbjct: 268 IGEDVDDLIGVAYLKDAVRATAFNPAAMERAVESIVRQPLLVPESKPVDDLFHEMQRSRQ 327

Query: 164 HMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDF 223
           H+A+V+DE+GG++G+VTIED +E IVGE+EDE+D     +  ++  + W + A   I D 
Sbjct: 328 HVAVVVDEYGGIAGMVTIEDAIEQIVGELEDEHDRTQRTEPEKIGDNKWKMPARTPIADL 387

Query: 224 NEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
            E F     +++VDT+ GL+ +  G +P  G +    G +     +  RR
Sbjct: 388 EEIFEIDIDEDDVDTVYGLLTKILGRVPIVGASAVTRGLRLTAVDSAGRR 437


>UniRef50_D2LWG5 Putative uncharacterized protein n=3 Tax=Bacillus
           RepID=D2LWG5_BACS4
          Length = 415

 Score =  142 bits (357), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 92/266 (34%), Positives = 140/266 (52%), Gaps = 1/266 (0%)

Query: 16  KGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           K F S L+ +         +EL  LI  S +  +IDE  R+++   +D  D  V +I+ P
Sbjct: 150 KIFVSKLIKKEKTAPSVTEEELKELISISEEEGVIDESERELVHRSLDFNDIIVAEIVTP 209

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  ++ +  N T+DE  +  I+  +SR PV   + D+I GIL  +D L           +
Sbjct: 210 RMDIVAIDVNNTVDEIKNTFIKERYSRIPVYEGNIDNIIGILSERDFLKAYIQLEYDVDI 269

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
            K+LR  V V ES R+  +L + +  + HMAIVIDE+GG  GL+T+EDILE IVGEI DE
Sbjct: 270 RKLLRDPVFVFESMRIHTLLPQLQKNKGHMAIVIDEYGGTEGLITLEDILEEIVGEIWDE 329

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
           +DE+ ++  +Q+   T  V A   ++DF         D    TIGG + + F  +P+  E
Sbjct: 330 HDEDINL-LKQVDPSTLIVHADCPLDDFVRKTKIELPDTPYHTIGGWLSEVFQRIPSVNE 388

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKI 281
            +  +    K+  AD RRI  + V +
Sbjct: 389 EVQYEHISLKIIDADERRIRAIEVSL 414


>UniRef50_A7VIV6 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VIV6_9CLOT
          Length = 268

 Score =  142 bits (357), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 82/255 (32%), Positives = 148/255 (58%), Gaps = 10/255 (3%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E K  +E+++++ +  +  LI +D  +M+  + + +++ VRD+M PRS ++ + ++ T+D
Sbjct: 11  EEKVEEEIISMVNEGNEQGLIHDDEVEMITNIFEFSEKEVRDVMTPRSDVVGIDKHTTMD 70

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
           E + +++E+ +SR+PV  +D D+I GIL  KD +     D    ++++++ +   V  +K
Sbjct: 71  ETIKIMLENNYSRYPVFDDDLDNIVGILYFKDFVKAYLQDKNQ-TIEQIMVEPTFVHPTK 129

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            +  + K  + ++ HM IV+DE+G   G++ +EDILE IVG I DEYD+++D     L+ 
Sbjct: 130 NISELFKRMQKEKIHMVIVVDEYGQTEGIIAMEDILEEIVGNIFDEYDDDEDD--IALAG 187

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI--DGYQFKV- 266
           H + V   A +++ +E  G  F DE+  T+ G ++   G LP   E IDI   GY F+  
Sbjct: 188 HGYIVGGRAELDELSEHLGIEFPDEDFQTLNGFMLYELGRLPYENEKIDITYKGYNFETI 247

Query: 267 ----AMADSRRIIQV 277
                M D  RI +V
Sbjct: 248 GIKDKMIDKVRITKV 262


>UniRef50_D1BUW5 CBS domain containing protein n=3 Tax=Micrococcineae
           RepID=D1BUW5_XYLCX
          Length = 476

 Score =  141 bits (356), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 85/244 (34%), Positives = 141/244 (57%), Gaps = 2/244 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +EL  L+   G++D+I+ED R++L  V ++     R++M+PR+ M+T+     L   
Sbjct: 163 PTEEELRDLVDRVGESDVIEEDERELLRSVFELGGTLTREVMVPRTDMVTIDAATPLRTA 222

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD--AEAFSMDKVLRQAVVVPESK 149
           + + + S  SR PV+ E  D + G+   KD+   + +D  A A  +  V R  V VPESK
Sbjct: 223 MSLYVRSGFSRVPVVGESVDDLLGVAYLKDVARLLDADPAATARPVSDVARPPVFVPESK 282

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            VD +L+E + +  H+A+VIDE+GGV+GLVT+EDILE +VGE+ DE+D   + +  +++ 
Sbjct: 283 PVDDLLREMQQKATHIALVIDEYGGVAGLVTVEDILEELVGELHDEHDRVIEEEPEEIAP 342

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
             + V A   +++  + F   F D++VDT GGL+ +A G +P  G   D+     +    
Sbjct: 343 GIFRVPARLPVDELGDLFDLRFDDDDVDTAGGLLAKAIGKVPLVGSAADVGELHLEAERI 402

Query: 270 DSRR 273
           + RR
Sbjct: 403 EGRR 406


>UniRef50_A5V8Y4 CBS domain containing protein n=9 Tax=Sphingomonadales
           RepID=A5V8Y4_SPHWW
          Length = 322

 Score =  141 bits (356), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 80/235 (34%), Positives = 132/235 (56%), Gaps = 4/235 (1%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
           R+ML  ++   ++ V DI +PR  ++ +      DE +    E+ HSR PV  ED DH+ 
Sbjct: 83  REMLRNILHFGERTVGDIGVPRGDIVAVPEAIGFDELVARFAEAEHSRLPVYGEDLDHVT 142

Query: 115 GILMAKDLLPFMRSDA-EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFG 173
           G++  KD+   + + A    ++  ++RQ   VP S R+  +L E R  R H+AIV++E+ 
Sbjct: 143 GMIHVKDVFRIIATGAARPATIAGLIRQPRYVPSSMRIIDLLAEMRETRTHLAIVLNEYS 202

Query: 174 GVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS- 232
           G  GLVTIED++E IVG+IEDE+DE++      L    W+  A A +ED         + 
Sbjct: 203 GTDGLVTIEDLVEEIVGDIEDEHDEKEADLLVPLDDAIWSADARAELEDVARLIDPRLAD 262

Query: 233 -DEEVDTIGGLVMQAFGHLPARGETID-IDGYQFKVAMADSRRIIQVHVKIPDDS 285
            D++V+T+GGL     G +P  G+ ++   G++ ++  AD RR+ Q+ +  P D+
Sbjct: 263 IDDDVETLGGLASALAGQVPQAGQIVEHPSGWRLEITDADERRVRQMLLHPPADA 317


>UniRef50_B3QAC3 CBS domain containing protein n=15 Tax=Rhizobiales
           RepID=B3QAC3_RHOPT
          Length = 381

 Score =  141 bits (356), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 92/300 (30%), Positives = 159/300 (53%), Gaps = 33/300 (11%)

Query: 23  LSQLFHGEPKN-RDELLALIRDSGQNDL-IDEDTRDMLEGVMDIADQRVRDIMIPRSQMI 80
           +  LF  +P + RD+L  ++  S  +D       R ML  ++ + D+R+ D+M+ R+ ++
Sbjct: 45  IRSLFGWKPGSVRDDLQVVLDTSPPDDTGFSTLERTMLRNILGLHDRRIADVMVHRADIV 104

Query: 81  TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE--------- 131
            +K++  L E L +  ++AHSR  V +E  D   GI+  +DL+ FM + A+         
Sbjct: 105 AIKQDIQLGELLSLFQDAAHSRLVVYNETLDDPVGIVHIRDLVAFMTAKAKVPPATVAKR 164

Query: 132 -----------------AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGG 174
                              +   ++R+ + VP S R   +L + ++ R H+A+V+DE+GG
Sbjct: 165 KKALPAGLDLRAIDLKMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGG 224

Query: 175 VSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF--- 231
             GLV+IEDI+E IVGEI+DE+D  +     + +  ++   A AS+ED     G  F   
Sbjct: 225 TDGLVSIEDIVEQIVGEIDDEHDSTEPPSIVRQADGSFIADARASLEDVRAMIGDQFVTG 284

Query: 232 -SDEEVDTIGGLVMQAFGHLPARGETIDIDG-YQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            + E+V+T+GG ++   G LP RGE I   G ++F+V  AD RR+ ++ +    + P P+
Sbjct: 285 EAGEDVETLGGYLVNHVGRLPVRGEVIAGPGTFEFEVLDADPRRVKRLRIGPRKERPAPR 344


>UniRef50_A9KLG3 Putative uncharacterized protein n=1 Tax=Clostridium
           phytofermentans ISDg RepID=A9KLG3_CLOPH
          Length = 487

 Score =  141 bits (356), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 76/257 (29%), Positives = 156/257 (60%), Gaps = 8/257 (3%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+++++ +  +  +++ +  +M+  +++  ++  +DIM  R +MI +     +++ L  
Sbjct: 186 EEIMSMVNEGHEQGVLEAEEAEMISNIIEFNEKAAKDIMTHRKKMIAINSALCIEDALRF 245

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKD-LLPFMRSDAEAFSMDKVLRQAVVVPESKRVDR 153
           +++  +SRFP+   D D+I G+L  KD +L F+    +   + KV R+   +P+++ +D 
Sbjct: 246 MLDENYSRFPLYDGDIDNIVGLLHLKDVMLYFLDPRLKVEPLSKVAREPYFIPDTQSIDV 305

Query: 154 MLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWT 213
           +  + ++++ HMAI IDE+G  +G+V +EDILE IVG+I+DEYD+E+++ + +L   ++ 
Sbjct: 306 LFHDMQTKKIHMAIAIDEYGQTAGIVAMEDILEEIVGDIQDEYDDEEEL-YTRLEDDSYL 364

Query: 214 VRALASIEDFNEAFGTHFSDEEV---DTIGGLVMQAFGHLPARGE--TIDIDGYQFKVAM 268
           +   AS+ED  +     F++E++   DT+ GL++    H+P   E  TI   GY++++  
Sbjct: 365 LSGEASLEDLEDILSLPFAEEDIKNYDTLNGLIVSLLDHIPGDDERATIRYCGYEYELME 424

Query: 269 ADSRRIIQVHV-KIPDD 284
             +R I  V V KIP++
Sbjct: 425 IQNRMITSVRVRKIPEE 441


>UniRef50_A0LRV3 Putative uncharacterized protein n=1 Tax=Acidothermus
           cellulolyticus 11B RepID=A0LRV3_ACIC1
          Length = 438

 Score =  141 bits (355), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 80/262 (30%), Positives = 143/262 (54%), Gaps = 13/262 (4%)

Query: 25  QLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
           +L  G+PK      + +EL  L+     ++ +  D R +++ V    D+R+R++++PR++
Sbjct: 166 RLLGGDPKAARESMSEEELRGLVTS---HEALGRDERQLIDEVFTAGDRRLREVLVPRTE 222

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD-AEAFSMDK 137
           +  L     + + L  +  + HSR+PV     D I G++  +DLL     +      +  
Sbjct: 223 VEFLDATMPVGQALAQLRSTMHSRYPVFRGSHDEIIGMVHVRDLLAAQAENRGRTVRVGD 282

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
           ++R   ++P+   V + L E R + + +A+V+DE+GG +G+VT+ED++E I+GEI DE+ 
Sbjct: 283 LVRPVKLLPDGLGVLQALSEMRREGHRLAVVVDEYGGTAGIVTLEDLVEEIIGEIRDEH- 341

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
             D +D    +     V  L   EDF E  G    D   +T+ G ++ A GH+P  GE +
Sbjct: 342 APDGVDAS--ASGEMIVDGLTHTEDFAEETGIRLPDGPYETVAGFMLAALGHIPGLGEWV 399

Query: 258 DIDGYQFKVAMADSRRIIQVHV 279
           D+DGY+F VA  D RR+ ++ +
Sbjct: 400 DVDGYRFTVAELDGRRVAKIKI 421


>UniRef50_A5ZVW9 Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC
           29174 RepID=A5ZVW9_9FIRM
          Length = 315

 Score =  141 bits (355), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 81/279 (29%), Positives = 157/279 (56%), Gaps = 14/279 (5%)

Query: 18  FFSLLLSQLFHGEPKN---RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           FF +     F GE ++     E+++++ ++ +  ++ +D  +M++ +    D+ V  +M 
Sbjct: 23  FFRVF--HFFKGEQEDSVTEKEIISMVDEAHEKGVLQKDEAEMIQNIFAFEDKEVGVVMT 80

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF- 133
            RS +     +  L + ++ ++E  +SR+PV  ED D I G++  KD L F   +  A  
Sbjct: 81  HRSSVAAFAMDDLLKDVVNHMMEEENSRYPVCGEDMDDIRGLIHYKDALKFFTQNPWAKF 140

Query: 134 ----SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
                +  ++R+A  VPE++ + ++ +  ++++ HMA+V+DE+G  +G+VT+ED++E IV
Sbjct: 141 KPLKELPGLIRKATFVPETRHIGQLFRTMQARQVHMAVVVDEYGQTAGIVTMEDLIEEIV 200

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G+I DEYDE  D  FR    ++  +  LAS++D  +     F D E++T+ G + +  GH
Sbjct: 201 GDIFDEYDESRDT-FRTQVDNSIIIDGLASLDDVEQELDIEFGDVEMETLNGYLTELLGH 259

Query: 250 LPAR---GETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           +P+R    + I  +GY+FK+    +R I +V  +  +D 
Sbjct: 260 IPSREDLDKEIVANGYRFKILSLGNRTIGRVRAEKINDK 298


>UniRef50_D2BD19 Putative uncharacterized protein n=1 Tax=Streptosporangium roseum
           DSM 43021 RepID=D2BD19_STRRD
          Length = 533

 Score =  141 bits (355), Expect = 3e-32,   Method: Compositional matrix adjust.
 Identities = 82/240 (34%), Positives = 136/240 (56%), Gaps = 10/240 (4%)

Query: 53  DTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDH 112
           D R ++  V     +++R++M+PR+++  +  +  L E   +     HSRFP+  +  D 
Sbjct: 197 DERHLIAEVFAAGKRQLREVMLPRTEVEFMSADTRLAEAAVLAAAMPHSRFPIYRDSYDD 256

Query: 113 IEGILMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDE 171
           I G +  +DLL P +    E  S    +R   +VP SKRV   L E R + +H+AIV+DE
Sbjct: 257 IVGFVHIRDLLDPVLTGSIEPISELVPIRPVKLVPTSKRVLATLSEMRGEGHHLAIVVDE 316

Query: 172 FGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVR--ALASIEDFNEAFGT 229
           +GG +G+VT+ED++E ++G+I DE+D ED+    Q+      V    LA++++     G 
Sbjct: 317 YGGTAGIVTLEDLVEELIGDIRDEHDVEDE----QVVLPAGEVELDGLANLDEVATETGI 372

Query: 230 HFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK---IPDDSP 286
             +D   +T+GG VM A GHLP  GE ++I G++  V   D RR+ +V +K   +P ++P
Sbjct: 373 RLADGPYETLGGFVMAALGHLPTLGERVEIPGFEMSVTDMDGRRVSRVRIKRRTVPPETP 432


>UniRef50_C7MLQ1 CBS domain-containing protein n=8 Tax=Coriobacteriaceae
           RepID=C7MLQ1_CRYCD
          Length = 443

 Score =  140 bits (354), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 86/250 (34%), Positives = 141/250 (56%), Gaps = 10/250 (4%)

Query: 23  LSQLFH------GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           L++LFH       +  + DE+  +++D   N+ +  D + M+  ++D+AD   RDIM PR
Sbjct: 164 LARLFHVKSVDERQAVSEDEIKYIVKD---NEELLPDEKRMIHEILDLADATARDIMTPR 220

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
           + +I ++  +T+ E L+ +  + +SR PV  ED D I G++  KDL+P +  D E  ++D
Sbjct: 221 ADIIFVEDTETVKETLNRMRGTGYSRLPVYHEDYDRIVGVVKYKDLIPAIMDDREDATVD 280

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
           +   +   VPE+K +  +L E ++ R  +AIV+DE+GG  GL+TIEDI+E IVGEI DE 
Sbjct: 281 EFTDEVYFVPETKDIFPLLSEMQTNRQQIAIVVDEYGGTDGLITIEDIVEEIVGEIIDET 340

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           D E      QL+   W V     ++D  E        ++ +TI G ++     +P  G++
Sbjct: 341 DLESRY-VTQLTDGEWLVDGSLPVDDAIELSWPLEESDDYETIAGWLIDMVDTIPQIGDS 399

Query: 257 IDIDGYQFKV 266
            D  GY+F V
Sbjct: 400 YDFGGYRFTV 409


>UniRef50_B2V0V1 CBS/transporter domain protein n=18 Tax=Clostridiales
           RepID=B2V0V1_CLOBA
          Length = 439

 Score =  140 bits (354), Expect = 4e-32,   Method: Compositional matrix adjust.
 Identities = 84/258 (32%), Positives = 152/258 (58%), Gaps = 4/258 (1%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  +++E+ +L+    ++ +I+E  ++M+  + +  D+   ++M PR+++  +  ++ L+
Sbjct: 182 EKVSKEEIKSLVEVGQEHGVINETEKEMINSIFEFDDKLADEVMTPRTEVYLINIDKPLE 241

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKD-LLPFMRSDAEAFSMDKVLRQAVVVPES 148
           E LD ++E  +SR PV  ED D+I GIL  KD +L   + + E  ++ ++L     VPE+
Sbjct: 242 EYLDELLEEKYSRVPVYEEDIDNIIGILYMKDFILEARKHEFENVNIREILHPPYFVPET 301

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K +D +  E +S + HMAI+IDE+GG SG+VTIED++E ++G I+DEYDEE+    +++ 
Sbjct: 302 KNIDDLFNELKSSKKHMAILIDEYGGFSGIVTIEDLVEEVMGNIDDEYDEEECF-VQKID 360

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE--TIDIDGYQFKV 266
            +T+ V  L  I+D N+        +E DTI G ++   G +P   E   I+ +   FK+
Sbjct: 361 SNTFIVNGLMPIDDLNDYLHIQLVSDECDTISGFLINIMGKIPNNIEEKVIEYENIIFKI 420

Query: 267 AMADSRRIIQVHVKIPDD 284
                +RI ++ + I  D
Sbjct: 421 ESIKEKRIEKIKICIQKD 438


>UniRef50_D2QA49 Hemolysins-like protein containing CBS domains n=12
           Tax=Bifidobacterium RepID=D2QA49_9BIFI
          Length = 473

 Score =  140 bits (353), Expect = 5e-32,   Method: Compositional matrix adjust.
 Identities = 82/229 (35%), Positives = 132/229 (57%), Gaps = 3/229 (1%)

Query: 47  NDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVI 106
           ND  D +  +ML  V+ +++   R+IM+PR+ MI ++R++TL+  L +   S  SR PVI
Sbjct: 201 NDF-DPEVSEMLRNVLMLSETLTREIMVPRTDMICVERDETLENMLKLCSRSGFSRVPVI 259

Query: 107 SEDKDHIEGILMAKDLLPFMRSDAEAFSMD--KVLRQAVVVPESKRVDRMLKEFRSQRYH 164
            +D D + GI   KD +     +  A S D   ++R  ++VPESK VD +  + +  R H
Sbjct: 260 GDDVDDLVGIAYLKDAVRATAFNPAALSRDVESIVRDPMLVPESKPVDDLFHQMQRTRQH 319

Query: 165 MAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN 224
           +A+V+DE+GG++GLVTIED +E IVGE+EDE+D     +  +L    W++ A  +I D  
Sbjct: 320 VAVVVDEYGGIAGLVTIEDTIEQIVGELEDEHDRTQHAEPERLGEKKWSMPARTTIADLE 379

Query: 225 EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
           E F     +++VDT+ GL+ +  G +P  G +    G +     +  RR
Sbjct: 380 EIFEIDIDEDDVDTVYGLLTKLLGRVPIVGASAVTRGLRLTAVDSAGRR 428


>UniRef50_C1A9X1 Hypothetical membrane protein n=1 Tax=Gemmatimonas aurantiaca T-27
           RepID=C1A9X1_GEMAT
          Length = 433

 Score =  140 bits (353), Expect = 5e-32,   Method: Compositional matrix adjust.
 Identities = 81/262 (30%), Positives = 142/262 (54%), Gaps = 10/262 (3%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   + +EL  L+  +  +  +DE    ML GV D  ++R  D+M PR++M+ +  +   
Sbjct: 176 GHVHSPEELRLLVMQARAHGTLDESDSAMLAGVFDFHNKRAVDVMRPRTEMVAIAEDVDQ 235

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
            E  +++    +SR+PV  E  D I G+ +AKD   ++R ++E+F + +VLR+ + VP +
Sbjct: 236 QELEEILRRERYSRYPVYRETADDIVGVFLAKDF--WLRENSESFELRQVLREPLFVPAT 293

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD--EEDDIDFRQ 206
           +  +R+L + R  R H+A+V+DEFGG +G+VT+ED++E +VG+I DEYD    D + F  
Sbjct: 294 RTAERVLDDLRRTRAHLAVVLDEFGGTAGIVTMEDLVEEVVGDIADEYDPLSRDALLFDG 353

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
           +     ++    S+ D          + +  T+GG      G LP  G+ +   G   +V
Sbjct: 354 VLELAGSM----SLVDVRSDHKLPIPEGDWSTLGGYAFATLGRLPHVGDRVAYPGGDLEV 409

Query: 267 AMADSRRI--IQVHVKIPDDSP 286
              D RR+  ++VH ++    P
Sbjct: 410 VAMDGRRVAALRVHKRVESTEP 431


>UniRef50_B1I646 Putative uncharacterized protein n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I646_DESAP
          Length = 431

 Score =  140 bits (353), Expect = 5e-32,   Method: Compositional matrix adjust.
 Identities = 74/232 (31%), Positives = 132/232 (56%), Gaps = 2/232 (0%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           +D + + +L  V D  D    D+M+PR+ ++ ++ + ++ + L ++ E+ HSR PV  ++
Sbjct: 198 LDREEQRLLWDVFDFGDAVAYDVMVPRTDVVGVETSTSVADTLRLMSETGHSRIPVYGQN 257

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVI 169
            D I+GI   KDL+P++    E   ++KV+R A VVP +  + ++L++ + +   MA+++
Sbjct: 258 LDDIKGIAGIKDLVPYLLRGEEQAPVEKVVRPAYVVPNTVPIRQLLRDLQKRGVSMAVIV 317

Query: 170 DEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT 229
           DEFGG  G+VT+E +LE +VGEI DEYD ED  +          V+  A +++ N     
Sbjct: 318 DEFGGTDGVVTVETLLEELVGEIRDEYDREDQ-EILSSEDGQAIVKGSAGVDEVNRQLKL 376

Query: 230 HFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
              + EE  TI G ++     +P  G+ + +DG   +VA   + RI+ V +K
Sbjct: 377 AIPESEEYHTIAGFILDQLNKVPKAGDRVTLDGTVLEVAKMKANRILMVSIK 428


>UniRef50_Q01P08 CBS domain containing protein n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01P08_SOLUE
          Length = 420

 Score =  140 bits (352), Expect = 7e-32,   Method: Compositional matrix adjust.
 Identities = 81/254 (31%), Positives = 143/254 (56%), Gaps = 8/254 (3%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           EP   + + ALI    +  LI+E+ R +++ V++  D+ VR++M PR  ++ +  + TL+
Sbjct: 163 EPTPAENIEALISAGTEEGLIEEEDRKLIQSVVEFGDKVVREVMTPRPNIVAIAADATLE 222

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
           +   ++I   +SR PV     D++ G +  +D+      + E  ++  ++R  ++VPE+K
Sbjct: 223 QLRQLVITEQYSRIPVYEGTIDNVIGFVHVRDMFELQEEEREKRTVRGLVRNIMLVPETK 282

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            V  +++  + +  HM IV+DE+G  +GL T+ED+LE+I+GEI DE+  E D D  +  R
Sbjct: 283 PVSVLMRRMQQENTHMVIVVDEYGNTAGLATMEDLLEVIIGEIRDEH--EPDSDVAEDGR 340

Query: 210 HTWTVRA---LASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
             + V     L  I D  + F  H  D+ E  T+GGLV +  G +P  GE ++ DG + +
Sbjct: 341 GGFIVSGSFDLDRITDLIDTF--HRGDDIESTTVGGLVSEWLGRVPKTGEFVERDGVRLE 398

Query: 266 VAMADSRRIIQVHV 279
           V  +D  R+ QV +
Sbjct: 399 VLASDELRVGQVRI 412


>UniRef50_A9VF50 Putative uncharacterized protein n=6 Tax=Bacillus
           RepID=A9VF50_BACWK
          Length = 437

 Score =  140 bits (352), Expect = 7e-32,   Method: Compositional matrix adjust.
 Identities = 80/256 (31%), Positives = 148/256 (57%), Gaps = 5/256 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H      +EL  ++ +S +   I++     +  + +  ++  ++IM+PR+++I L  + +
Sbjct: 175 HDVAHTEEELRLILSESYERGEINQAEYKYVNNIFEFDNRIAKEIMVPRTEIIGLHVDNS 234

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL-LPFMRSDAEAF-SMDKVLRQAVVV 145
           L + + +I +  ++R+PV  EDKD I G++  KD  + +M  + + F S+    R  + V
Sbjct: 235 LADHMKIIRDEKYTRYPVFGEDKDEIIGMVNVKDFFIRYMNKETKEFNSIQSYTRPVIEV 294

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFR 205
            E+  +  +L + + +R  +A++ DE+GG +G+VTIEDILE IVGEI DEYDE++    +
Sbjct: 295 IETIPIHNLLLQMQKKRIPLAVLYDEYGGTAGIVTIEDILEEIVGEIRDEYDEDERPPIQ 354

Query: 206 QLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGG-LVMQAFGHLPARGETIDIDGYQF 264
           Q++     V     I + N+  G H +D +VDTIGG ++MQ +      G+T++ +GY F
Sbjct: 355 QMNEGHLVVEGKVLISELNDLLGLHMNDSDVDTIGGWILMQNYD--IQEGQTVNSEGYAF 412

Query: 265 KVAMADSRRIIQVHVK 280
           K+   D  +I +V ++
Sbjct: 413 KILSKDPHQIKRVEIQ 428


>UniRef50_D2RTA7 Putative uncharacterized protein n=3 Tax=Haloterrigena turkmenica
           DSM 5511 RepID=D2RTA7_9EURY
          Length = 467

 Score =  139 bits (351), Expect = 9e-32,   Method: Compositional matrix adjust.
 Identities = 86/252 (34%), Positives = 140/252 (55%), Gaps = 7/252 (2%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
            RDE+  +I    +  +++E+  +ML+ +    +  V+++M PR  M  + ++  +DE +
Sbjct: 193 TRDEIQEMIESGEREGVLEEEEHEMLQRIFRFNNTIVKEVMTPRLDMTAVPKDAGIDEAI 252

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDL---LPFMRSDAEAFSMDKVLRQAVVVPESK 149
           +  I+S H+R PV     D++ G++  +DL   L +  ++A+   ++ +++  + VPESK
Sbjct: 253 ETCIQSGHARVPVYEGSLDNVLGVVHIRDLVRDLNYGETEADDLELEDLIQPTLHVPESK 312

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            VD +L E R  R HMAIVIDEFG   GLVT+ED++E IVGEI    ++E      QL  
Sbjct: 313 NVDELLTEMRENRMHMAIVIDEFGTTEGLVTVEDMIEEIVGEILKSGEDE---PIEQLDD 369

Query: 210 HTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
            T  VR   +IED NEA      + EE +TI G +    G L   GE I  DG +  V  
Sbjct: 370 RTVIVRGEVNIEDVNEALEIDLPEGEEFETIAGFIFNRAGRLVEEGEEITYDGVRITVET 429

Query: 269 ADSRRIIQVHVK 280
            ++ RI++  ++
Sbjct: 430 VENTRIMKARLR 441


>UniRef50_B0A8E0 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0A8E0_9CLOT
          Length = 412

 Score =  139 bits (351), Expect = 9e-32,   Method: Compositional matrix adjust.
 Identities = 76/232 (32%), Positives = 140/232 (60%), Gaps = 1/232 (0%)

Query: 48  DLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVIS 107
           D  D D +D ++ +    ++++R++++PR+ M+ L  + + +   ++I E  ++R+PV  
Sbjct: 178 DKYDADKKDFMDNIFSFEEKQIREVLVPRTDMVCLDLDDSEEYIFNLIKEEGYTRYPVCG 237

Query: 108 EDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAI 167
           +DKD + G +  +DL    +   +   + K+LR+   V ES+   R+L++ R  R  MAI
Sbjct: 238 KDKDDLLGFIHIRDLYN-QKLIEDKVDLTKILRKITYVSESELTSRVLEKLRKDRVQMAI 296

Query: 168 VIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAF 227
           V+DE+GG SG+VT+EDILE IVGEI+DE+DE++++D ++L + ++ V+  A+I + N+  
Sbjct: 297 VVDEYGGTSGIVTVEDILEEIVGEIQDEFDEDEELDIKKLDKDSYIVQGTATITEINKVL 356

Query: 228 GTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
                 +  D+IGG +    G      +++D  GY+FKV   D  R+I + +
Sbjct: 357 NIEIEKDGFDSIGGWMFFMLGMDIEINQSVDFSGYRFKVVEIDKFRVISIKI 408


>UniRef50_B9XIF8 Putative uncharacterized protein n=1 Tax=bacterium Ellin514
           RepID=B9XIF8_9BACT
          Length = 451

 Score =  139 bits (351), Expect = 9e-32,   Method: Compositional matrix adjust.
 Identities = 75/222 (33%), Positives = 128/222 (57%), Gaps = 4/222 (1%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISE-DKDHI 113
           RD++   +D+  + VR++M PR ++  L    ++ ECLDV  +S +SRFP+    D D  
Sbjct: 208 RDIVMNALDLRLRIVREVMRPRQEITFLDTEASITECLDVAEKSRYSRFPLCENGDLDKT 267

Query: 114 EGILMAKDLLPFMRSDAEAFS-MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEF 172
            G++  KDL   MR  A + + +  V+R+ + VPE+ R++++L+ F  ++ H AIV+DE+
Sbjct: 268 LGVIHIKDLFA-MRIKARSGADLKPVVRKLIYVPETARLEKLLQLFLDRKLHFAIVVDEY 326

Query: 173 GGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS 232
           GG  G+VT+E++LE +VG+I+DE+D+E  +   + S  TW V     + + +E  G    
Sbjct: 327 GGTVGMVTLENVLEELVGQIQDEFDQEKPL-VTKTSGQTWEVAGTLPLHELSEIVGETLQ 385

Query: 233 DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
           +E V T+ G V    G  P  G+ + +  Y  KV   +  R+
Sbjct: 386 EEGVTTVSGWVTHRLGGFPKMGDIVTVGDYSLKVEEMEGMRV 427


>UniRef50_Q93NC4 Hemolysin TlyC n=3 Tax=Cystobacterineae RepID=Q93NC4_MYXXA
          Length = 463

 Score =  139 bits (350), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 79/256 (30%), Positives = 141/256 (55%), Gaps = 8/256 (3%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  + DELL ++  S Q   I     ++LE  +++A +  R +M+PR+Q+  L   + L+
Sbjct: 182 EAHSEDELLVILHSSAQAGAITTARAELLERALEMAQKTARQVMVPRNQVKFLDVEEPLE 241

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
           +C+     + H+  PV   + D +EG++ AKDL  F+ S  E  S+ +V R  + +PE  
Sbjct: 242 KCIADARAAGHTWLPVCRGNLDEVEGVVNAKDLF-FLLSRGELRSLAQVQRPVLFIPEGA 300

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            ++++L EFR +R   A+V+DE GG SGLVTI D++  +VG++ +     D++  R L  
Sbjct: 301 TLEQLLAEFRRRRRQTALVVDEHGGTSGLVTIADVVAEVVGDVAELGRRMDEV--RALPG 358

Query: 210 HTWTVRALASIEDFNEAFGTHF-----SDEEVDTIGGLVMQAFGHLPARGETIDIDGYQF 264
             + +   A ++D  E    +F      + EV TI G +M   G +P +G+T+ +D ++ 
Sbjct: 359 GRFELPGTAQLDDLEERLDVNFDLDEDEEGEVTTIAGYLMTRLGRVPVKGDTLRLDMWRI 418

Query: 265 KVAMADSRRIIQVHVK 280
            V   +  R+++V V+
Sbjct: 419 VVDAVEGPRVVRVTVE 434


>UniRef50_A0RW86 Hemolysin n=4 Tax=Thaumarchaeota RepID=A0RW86_CENSY
          Length = 418

 Score =  139 bits (350), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 77/246 (31%), Positives = 132/246 (53%), Gaps = 1/246 (0%)

Query: 22  LLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT 81
           L    ++  P   DE+  ++     +  I+E+  +++ G +   D  +R +M PR++M T
Sbjct: 154 LTGSSYYAPPITEDEIRGVVEQGLADKAIEEEEGELVHGALGFDDTIIRAVMTPRTRMFT 213

Query: 82  LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQ 141
           L     L E L +I +  HSR P++ E  + I G + A D+L  +  D    +++++ R+
Sbjct: 214 LNAKMLLFEALPLINQRGHSRIPILGEGGNEIVGFVHAGDILKELEHDKRVVTLEQIARK 273

Query: 142 AVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD 201
            V V + KRV  +LKE + ++ HMA+VIDE GG+ GLVT+ED+LE IVGEIEDE D+   
Sbjct: 274 PVFVSQEKRVSSLLKEMQGRKVHMAMVIDEHGGIVGLVTLEDLLEEIVGEIEDETDKTRP 333

Query: 202 IDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDID 260
            ++  + R T        I   NE F     + E+  ++ GL+ +    +P  G+ +++ 
Sbjct: 334 QEYHSIDRDTIITSGDIEINRINEIFKADVPEGEDYASLSGLLHERLHDIPQEGDKVEVG 393

Query: 261 GYQFKV 266
             +  V
Sbjct: 394 SLRIIV 399


>UniRef50_B6JNY8 Hemolysin domain-containing protein n=23 Tax=Campylobacterales
           RepID=B6JNY8_HELP2
          Length = 445

 Score =  139 bits (350), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 76/248 (30%), Positives = 138/248 (55%), Gaps = 2/248 (0%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H    + +EL  ++ +S +  +ID    ++++  +D +D   ++IM PR  M+ L    +
Sbjct: 188 HDGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVCLDEENS 247

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
            +E +D++++S  +R+P     KD+I G++  +DLL       +    ++++R+ ++VPE
Sbjct: 248 YEENIDIVLKSRFTRYPYCKGSKDNIIGMVHIRDLLSRSIFTPKMHDFNQIVRKMIIVPE 307

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           S  + ++L + + ++ H A+VIDE+GG +GL+T+EDI+E I+GEI DEYD + +    +L
Sbjct: 308 SASISQILIKMKKEQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQE-GVNKL 366

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
               + +  +  +E   E     F  E E  T+GG V      +P  G+TI   GY F+V
Sbjct: 367 EEGVFELEGMLDLESVEEVLHIEFDKECEQVTLGGYVFSLLERMPMEGDTIVSHGYSFEV 426

Query: 267 AMADSRRI 274
              D  RI
Sbjct: 427 LSVDGARI 434


>UniRef50_C5VDL5 CBS domain containing protein n=3 Tax=Corynebacterium
           RepID=C5VDL5_9CORY
          Length = 453

 Score =  139 bits (349), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 84/239 (35%), Positives = 135/239 (56%), Gaps = 17/239 (7%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           I+ D+R M++ V D++D   R++M+PR  M+ ++  +   + L + I+S HSR PVI E 
Sbjct: 184 IEVDSR-MVQNVFDLSDSIAREVMVPRPDMVWIESGKLASQALTLCIKSGHSRIPVIGES 242

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFS---MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMA 166
            D I G++  KD++  M S  +      +D+V+R A  VP+SKR+D +L E + +R+H+A
Sbjct: 243 VDDIVGVVYLKDVVQRMHSPTKGDKNPLVDEVMRTAHFVPDSKRLDDLLDEMQRERFHIA 302

Query: 167 IVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA-------- 218
           +++DEFGGV+GL++IEDILE IVGEI DEYD  +     Q     +  R ++        
Sbjct: 303 LLVDEFGGVAGLISIEDILEEIVGEITDEYDSAEITPIVQDPNDPYKYRVVSRLQLDDLV 362

Query: 219 -SIEDFNEAFGTHFSDE---EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
             IED +     +F  E   ++DT+ GL+    G +P     ++  G + K      RR
Sbjct: 363 ERIED-DHHITINFDPEILDQIDTVAGLIAYEKGRVPLPNTEVETSGLRLKAIGGRDRR 420


>UniRef50_D2QT15 Gliding motility-associated protein GldE n=1 Tax=Spirosoma linguale
           DSM 74 RepID=D2QT15_9SPHI
          Length = 453

 Score =  139 bits (349), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 91/268 (33%), Positives = 152/268 (56%), Gaps = 8/268 (2%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
            G   + +EL   +  +G N  ++E  +++L+G+++ ++   R +M  R  +  ++ + T
Sbjct: 184 KGYKLSVEELSQAVELTGTNATVEE--KEILKGIVNFSNLTARQVMRARLDISAVEDDLT 241

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
             E ++ I  S +SR PV  E  D IEGIL  KDLL  +  D ++F    +LR A  +PE
Sbjct: 242 FSELMEQINLSGYSRVPVYKESLDQIEGILYIKDLLTHIHED-DSFQWLSLLRPAFFIPE 300

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +K+VD +L++F+ +R HMAIV+DE+GG  GLVT+EDI+E I G+I DE+D+E  + +R+ 
Sbjct: 301 NKKVDDLLQDFQKKRVHMAIVVDEYGGTRGLVTLEDIIEEIFGDINDEFDDETPLGYRRE 360

Query: 208 SRHTWTVRALASIEDFNEAF---GTHFSDEEVD--TIGGLVMQAFGHLPARGETIDIDGY 262
             +T        I D         T F   + D  ++GGL+++ F  LP  GE +    +
Sbjct: 361 DENTVVFEGKMPITDVCRILNVDATTFEAVQGDSESLGGLLLELFNRLPKSGEEVVYANF 420

Query: 263 QFKVAMADSRRIIQVHVKIPDDSPQPKL 290
            F++  AD +RI +V V+  D   Q ++
Sbjct: 421 TFQIISADDKRINEVRVRKDDTVKQEQI 448


>UniRef50_C7DFD3 CBS domain protein n=6 Tax=Rhodobacteraceae RepID=C7DFD3_9RHOB
          Length = 456

 Score =  139 bits (349), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 79/257 (30%), Positives = 142/257 (55%), Gaps = 10/257 (3%)

Query: 34  RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLD 93
           R+E+   ++      +++++ RD + G +D+AD+ V +IM+ RS +  +    T ++ L+
Sbjct: 190 REEIQGALQLGHSEGVVEKEDRDRILGALDLADRTVEEIMLHRSGIEMIDAGNTPEDILN 249

Query: 94  VIIESAHSRFPVISEDKDHIEGILMAKDLL----PFMRSDAEA------FSMDKVLRQAV 143
             + S H+R P+  ++ ++I G++ AKDLL      +R+  E       F++ +V  +  
Sbjct: 250 QCLASKHTRLPIYKDEPENIIGVIHAKDLLRAVNTLLRTPGEDASSLADFNVIEVAMEPY 309

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
            VPE+  +D  +++F ++  H A+V+DE+G + GL+T+EDILE IVGEI DE+D  +D  
Sbjct: 310 FVPETTPLDDQMRQFLARHTHFALVVDEYGALQGLITLEDILEEIVGEITDEFDGGEDNQ 369

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
             Q    T+ V    +I D N A      D+E +T+ GLV+     +P  G+     G++
Sbjct: 370 LAQSDDGTFMVEGNMTIRDLNRANDWSLPDDEANTVAGLVIHEAQMIPTVGQVFSFHGFR 429

Query: 264 FKVAMADSRRIIQVHVK 280
           F+V      RI  + V+
Sbjct: 430 FEVTEKQKNRIATLKVR 446


>UniRef50_B6FN86 Putative uncharacterized protein n=2 Tax=Clostridium
           RepID=B6FN86_9CLOT
          Length = 282

 Score =  138 bits (348), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 79/248 (31%), Positives = 133/248 (53%), Gaps = 16/248 (6%)

Query: 48  DLIDEDTRD---------MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIES 98
           D++DE  R          M+  +    ++  + IM  R  M+ L   +TL+  L  I+E 
Sbjct: 31  DMVDEGYRQGVFLSSEAQMIRNIFAYGEKDAKSIMTHRKHMVALDGEETLENALTFILEQ 90

Query: 99  AHSRFPVISEDKDHIEGILMAKDLLPFMRSDA----EAFSMDKVLRQAVVVPESKRVDRM 154
             SRFPV  ED D I G +  +D +    ++         +++ +R    +PE++ +D++
Sbjct: 91  NKSRFPVYEEDIDSIIGTIHLRDAMKCYFNEQLRHIPIKQLEEYIRPVSFIPETRSIDKL 150

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
           LK+ +  +YHMAIVIDE+G  +GLVT+EDI+E IVG I+DEYDEE+++  RQ +  ++  
Sbjct: 151 LKKMQEGKYHMAIVIDEYGQTAGLVTMEDIIEEIVGNIQDEYDEEEEL-IRQEADGSYLA 209

Query: 215 RALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET--IDIDGYQFKVAMADSR 272
             +  +ED  E  G  F +E+ +T+ G ++     +P   E   +   GY F+V   ++ 
Sbjct: 210 DGMTEVEDLEELLGIQFEEEDYETLNGFLIFHLERIPTEEENCVVSYGGYDFQVLSMENN 269

Query: 273 RIIQVHVK 280
            I  V +K
Sbjct: 270 IIKTVQIK 277


>UniRef50_B7GEW2 Hemolysin related protein containing CBS domains n=8
           Tax=Bacillaceae RepID=B7GEW2_ANOFW
          Length = 421

 Score =  138 bits (348), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 82/247 (33%), Positives = 137/247 (55%), Gaps = 2/247 (0%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+  ++  S +  +ID   ++++   +D  D  V +I  PR  M+ ++ NQ ++E  D+
Sbjct: 169 EEIKVMVNLSEEEGVIDNKEKELVHRSLDFNDILVGEIFTPRIDMVAVEVNQPVEEIRDI 228

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
            +   +SR PV   D D++ GIL   D    +    E  ++ ++LR  + V ES R+  +
Sbjct: 229 FLRERYSRVPVYEGDIDNVIGILSESDFFSQLVQGKEV-NVRELLRTPLFVVESMRISTL 287

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
           L E +  + HMAIVIDEFGG SGL+T+EDILE IVGEI DE+DE     F++++ + +  
Sbjct: 288 LPELQKSKVHMAIVIDEFGGTSGLITLEDILEQIVGEIWDEHDEAVK-TFQKINDYEYEF 346

Query: 215 RALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
            A   +++F    G    +    T+GG V + F  +P  GE+ + +     V   ++RRI
Sbjct: 347 NAELPLDEFCHILGIDELESSSHTLGGWVFEMFERIPTVGESFEYETLTVTVRQVENRRI 406

Query: 275 IQVHVKI 281
            +V V+I
Sbjct: 407 RKVLVRI 413


>UniRef50_Q1IKR7 Putative uncharacterized protein n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IKR7_ACIBL
          Length = 455

 Score =  138 bits (347), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 81/261 (31%), Positives = 141/261 (54%), Gaps = 16/261 (6%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   + +EL  ++  S +  L+     +M+   +D+ +  VR+IM+PR  + +L  + TL
Sbjct: 178 GGVHSPEELKLMVTASRKFGLVPRLQEEMINRAIDLENISVREIMVPRPDIFSLPGHMTL 237

Query: 89  DECLDVIIESAHSRFPVISEDK--DHIEGILMAKDLLPFMRSD------------AEAFS 134
           DE +  +++  HSR P+   ++  +HI G+L AKDL+ +MR              A    
Sbjct: 238 DEAVQRVVDEQHSRIPIYDAERGPEHIIGVLYAKDLMRWMRYRIARLQQNRPARIASNLK 297

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +  ++R+ +VVPE+K +  +L+EF+ ++ H+A+V+DEFG  +G+VT+ED+LE +VGEIED
Sbjct: 298 VQHIMREVLVVPETKPLTDLLEEFKERKRHLAVVVDEFGSTAGVVTVEDVLEELVGEIED 357

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPAR 253
           E+D  ++         T  +    +I D    +      DE  +T+ G VM     +P  
Sbjct: 358 EHDVPEESALTP-GGTTLVLDGGINIRDLESQYQVRLPRDEGFETLAGFVMTRLQRIPRE 416

Query: 254 GETIDIDGYQFKVAMADSRRI 274
           G++     Y+F V   + RRI
Sbjct: 417 GDSFAFHNYRFTVLEMEGRRI 437


>UniRef50_C7MD87 CBS domain-containing protein n=1 Tax=Brachybacterium faecium DSM
           4810 RepID=C7MD87_BRAFD
          Length = 444

 Score =  137 bits (346), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 72/231 (31%), Positives = 132/231 (57%), Gaps = 4/231 (1%)

Query: 46  QNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPV 105
           +++ + E  RDM++GV D+    VR++M+PR  M+TL  + + ++ + + + S +SR PV
Sbjct: 187 EDEHVREGERDMIQGVFDLRGTMVRELMVPRPDMVTLSADASAEKAMRLFVRSGYSRIPV 246

Query: 106 ISEDKDHIEGILMAKDLLPFMRSDAEAFS---MDKVLRQAVVVPESKRVDRMLKEFRSQR 162
           I +  D + G+L  KD++  + S  +      + +++R A   PE    D +L + ++  
Sbjct: 247 IGDSVDDLRGMLYVKDVMRAIHSPWDPRPQRPVHEIMRAARFAPEFLAADAVLAQMQTSH 306

Query: 163 YHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIED 222
            H+ +++DE+GGV+G+VTIEDILE IVG+I DE+D  +  +   L    + V A A + +
Sbjct: 307 VHITVLVDEYGGVAGIVTIEDILEEIVGDIADEHDRREP-EIEDLGEGRYRVPARAGLSE 365

Query: 223 FNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
             + FG    D+++D++GGL+ +  G +P  G      G + +   +  RR
Sbjct: 366 VGDLFGLELDDDDIDSVGGLLAKVTGRVPIPGTHAITHGLELEAEKSTGRR 416


>UniRef50_C7RPW0 Putative uncharacterized protein n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RPW0_9PROT
          Length = 460

 Score =  137 bits (346), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 89/282 (31%), Positives = 146/282 (51%), Gaps = 10/282 (3%)

Query: 18  FFSLLLS-QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           F +L++  Q   G     D +  L++D+     +D      +E + D  ++ +RD+M PR
Sbjct: 152 FITLIVGKQRSQGNLVTEDMIRTLVQDAVGEGALDSQEAQYIEKIFDFGNKVLRDVMRPR 211

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF----MRSDAEA 132
           S +  L  +  + E +  I  +  SR+PV    +D I G+L  +DLL      +  D++ 
Sbjct: 212 SDIQFLSADLPVPELIAQIKATRQSRYPVFRGHRDTILGVLYTRDLLGVDLARLERDSQG 271

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
           F   K+LRQA   PESK    +   FR ++   A+++DE+GGV+GLVT+ED+LE + GEI
Sbjct: 272 FR--KLLRQAHFFPESKPAVELFHTFRQRKLSFALIVDEYGGVTGLVTMEDLLECVFGEI 329

Query: 193 EDEYDEEDDID--FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
               D +        +L+     + A  S+ DFN+AF    +  + +T+ G ++  FG L
Sbjct: 330 SSPSDVDTASQHLVSELADGRRLIDAGMSLGDFNQAFAVTIASVDAETLAGALLDTFGEL 389

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHV-KIPDDSPQPKLD 291
           PA G T  + G QF V   +  RI +V V ++P+   +P  D
Sbjct: 390 PACGATTVLGGLQFTVEGIEHNRITRVLVERLPEAIEKPASD 431


>UniRef50_B8ETG8 CBS domain containing protein n=2 Tax=Beijerinckiaceae
           RepID=B8ETG8_METSB
          Length = 357

 Score =  137 bits (345), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 95/317 (29%), Positives = 152/317 (47%), Gaps = 50/317 (15%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +K   F  L S    G P  RD++   + DS     +    R ML+ V+ + + +V D+M
Sbjct: 22  SKPNLFDRLRSIFGVGGPSIRDDIQDALADSSTAVDVSPQERAMLKNVLGLHEVQVEDVM 81

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM------- 126
           +PR+ ++ +  + +L + L     + HSR PV  +  D   G++  +DL+ +        
Sbjct: 82  VPRADIVAVPLDMSLADVLSTFRTAGHSRLPVHGDTLDDPRGMIHIRDLVAYFAAGLPEP 141

Query: 127 ---------------------------RSDAEA------------FSMDKVLRQAVVVPE 147
                                      RS+  A             S   +LR  + VP 
Sbjct: 142 AHRGEQDFGEAAPETPSGAAQPRELAPRSEPAAAKLWAFPDLDIPLSQANLLRPVLFVPP 201

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           S     +L   ++ R HMA+VIDE+GG  GL +IEDI+E+IVG+IEDE+D ++     + 
Sbjct: 202 SMPALDLLVRMQATRTHMALVIDEYGGTDGLASIEDIVEMIVGDIEDEHDFDESPKIEEA 261

Query: 208 SRHTWTVRALASIEDFNEAFG---THFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
              ++ V A A +ED +EA     T  SD EEV+T+GGL+    GH+P RGE I     +
Sbjct: 262 PDGSFIVDARAGLEDVSEAIKADLTAISDAEEVETVGGLISTLAGHVPVRGEIITEGDIE 321

Query: 264 FKVAMADSRRIIQVHVK 280
           F++  AD RR+ +V ++
Sbjct: 322 FEILDADPRRVKRVRIR 338


>UniRef50_C1YNF1 CBS domain-containing protein n=1 Tax=Nocardiopsis dassonvillei
           subsp. dassonvillei DSM 43111 RepID=C1YNF1_NOCDA
          Length = 454

 Score =  137 bits (345), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 87/249 (34%), Positives = 135/249 (54%), Gaps = 13/249 (5%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           EL  L+  + + ++ID +   M+  V  + D  VR++M+PR  ++   R    D  L + 
Sbjct: 177 ELRQLVDLAERGEVIDPEESQMIHSVFKLDDTPVREVMVPRPDIVFTSREADADAVLTLA 236

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA---------FSMDKVLRQAVVVP 146
           + S +SR PV  ED+D + GI+  KDL+  +R    A          +   V+RQA  VP
Sbjct: 237 LASGYSRIPVTGEDEDDVVGIVYLKDLVYQLRDRWAAAAGTDDEVPLTAGDVMRQANYVP 296

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE-DDIDFR 205
           ++K +D +L+E + QR H+A+ IDE+GG +GLVT+EDI+E IVGEI DEYD E   + + 
Sbjct: 297 DTKPIDELLREMQQQRNHVAVAIDEYGGTAGLVTLEDIVEEIVGEITDEYDHEIPPVAWL 356

Query: 206 QLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQF 264
              R   T R    + + +E F     D  +V+T+GGLV    G +P  G+  +  G + 
Sbjct: 357 DADRVRVTAR--LPLGELDELFPDRDLDVADVETVGGLVAFVLGRVPVGGDRAEYAGLRL 414

Query: 265 KVAMADSRR 273
            +    SRR
Sbjct: 415 TLEGKSSRR 423


>UniRef50_D1N3F2 Putative uncharacterized protein n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N3F2_9BACT
          Length = 445

 Score =  137 bits (345), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 78/234 (33%), Positives = 125/234 (53%), Gaps = 3/234 (1%)

Query: 46  QNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPV 105
           +N  I+ D + M+E V +  +    ++M  R++M+ L      +E   V++    SR PV
Sbjct: 199 ENGAIESDEKRMIENVFEFNNTTAAEVMTHRTEMVALDIEAPPEEVEKVLMSCGFSRVPV 258

Query: 106 ISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHM 165
             ED D I G L  ++ L        A  + K+L+   + PE+ R + + +  +S+++ M
Sbjct: 259 YREDIDEIIGFLHFREYLSAKVQGNSAPDIRKLLKPVYLAPETMRANILFRNMQSKKFGM 318

Query: 166 AIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNE 225
           AI++DEFGG SGLVTIED+LE IVG + DEYDE  DI+  QL    W +     +++ + 
Sbjct: 319 AIILDEFGGTSGLVTIEDLLEEIVGSLYDEYDEA-DIEIEQLGEGEWRIDGSMRLDEISR 377

Query: 226 AFGTHFSDEEVDTIGGLVMQAFGHLPARGETID--IDGYQFKVAMADSRRIIQV 277
                  +EE DTIGGLV      +P  G T++  + G   +V   + RR+ +V
Sbjct: 378 RLDLALPEEEYDTIGGLVFGMLNEVPTVGATVELPVSGISIRVESVEERRVDKV 431


>UniRef50_UPI0001973384 hypothetical protein ClM62_01605 n=1 Tax=Clostridium sp. M62/1
           RepID=UPI0001973384
          Length = 470

 Score =  137 bits (344), Expect = 5e-31,   Method: Compositional matrix adjust.
 Identities = 83/234 (35%), Positives = 128/234 (54%), Gaps = 4/234 (1%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           I ED  + ++ V D  D  +   M   S ++ L  + +  E L +I ES  SR PV ++D
Sbjct: 202 IAEDENEWIQNVFDFRDTSILSAMTRESDIVNLFEDSSEQEILKIIRESGLSRLPVYTKD 261

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVI 169
            + ++GIL  ++ L  + +  +  S+ ++L QA  VPES   D + ++ ++++ HMAIV+
Sbjct: 262 HEDVKGILYTREYLLNLTAK-QPKSLSQLLHQAYFVPESIHADDLFRDMQTKKVHMAIVV 320

Query: 170 DEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT 229
           DE+G +SGL+T+ED+LE IVG I DE+D   D +  ++S + W       IED  E    
Sbjct: 321 DEYGNISGLITMEDLLEEIVGSIYDEFDRVIDPEIERISENLWRFPGDTLIEDVEEQMDI 380

Query: 230 HFSD-EEVDTIGGLVMQAFGHLPARGETID--IDGYQFKVAMADSRRIIQVHVK 280
              D EE DTIGG+V+     +P  G T+D  I+G          RRI  V VK
Sbjct: 381 TLPDQEEYDTIGGMVLSCLHTIPKDGTTVDVEINGLSLHAEKIVGRRIESVLVK 434


>UniRef50_D0WN55 Integral membrane transporter with CBS domain n=1 Tax=Actinomyces
           sp. oral taxon 848 str. F0332 RepID=D0WN55_9ACTO
          Length = 415

 Score =  137 bits (344), Expect = 6e-31,   Method: Compositional matrix adjust.
 Identities = 82/241 (34%), Positives = 142/241 (58%), Gaps = 4/241 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           D+L  ++     + ++DE  R++L+ V D     VR++M+PR+ M+++  +  LD+ + +
Sbjct: 159 DQLAVMVERVSDSTVLDESDRELLQSVFDFNHTLVREVMVPRTDMVSIGIDAPLDKAMSL 218

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLP-FMRSDAEAFSMDKVLRQAVVVPESKRVDR 153
              S  SR PV+ E  D + G++  KD+L  ++R + E+ ++  ++R+ V VPE+K VD 
Sbjct: 219 FTRSGFSRVPVVGESADDLHGVVYLKDVLRRWLRGNTESLTVADLMREPVFVPETKVVDD 278

Query: 154 MLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE-DDIDFRQLSRHTW 212
           +++E ++ + H+A+V+DE+GG++GLVTIED++E +VGEI DE+D    ++D   +    +
Sbjct: 279 LMREMQANQVHIALVVDEYGGIAGLVTIEDLVEELVGEISDEHDRSAPEVDV--VEEGVY 336

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V A   I D  E FG    D++VDT+GGL  +  G +P  G    I G          R
Sbjct: 337 RVPARLPIADLGELFGVKLDDDDVDTVGGLFAKLIGRVPIAGSRASIGGISLTADRFQGR 396

Query: 273 R 273
           R
Sbjct: 397 R 397


>UniRef50_A4EBJ7 Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens
           ATCC 25986 RepID=A4EBJ7_9ACTN
          Length = 457

 Score =  136 bits (343), Expect = 7e-31,   Method: Compositional matrix adjust.
 Identities = 82/243 (33%), Positives = 137/243 (56%), Gaps = 4/243 (1%)

Query: 44  SGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRF 103
           S Q+DL+DE+ R M+  + D+ D   R++M+PR      + ++T+ + L  + ++  SR 
Sbjct: 191 SEQDDLLDEEKR-MIHEIFDLGDTVAREVMVPRVDTTMCEDDETVADVLSTMRQTGFSRI 249

Query: 104 PVISEDKDHIEGILMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQR 162
           PV  ED D++ GI   KDL+ P +    +   +   LR A  VP++K +  +L E ++  
Sbjct: 250 PVYHEDPDNVAGIAHIKDLIQPALDGKGDQ-PIAGFLRDATFVPDTKDILPLLSEMQTSH 308

Query: 163 YHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIED 222
             + +V+DE+GG +G++TIEDI+E IVGEIEDE+D  D+    +LSR  W V    S +D
Sbjct: 309 DQIVVVVDEYGGTAGIITIEDIVEEIVGEIEDEFD-PDNKYLTRLSRREWLVDGRFSCDD 367

Query: 223 FNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
             E        ++ +TI G +++    +P  GE  ++ GY+FKV     +RI  + V  P
Sbjct: 368 AIELGWPLEESDDYETIAGWILELCDSVPDIGEVFEVAGYKFKVQSMRGQRISLIRVIAP 427

Query: 283 DDS 285
            ++
Sbjct: 428 AET 430


>UniRef50_Q253J4 Hemolysin n=3 Tax=Chlamydophila RepID=Q253J4_CHLFF
          Length = 379

 Score =  136 bits (342), Expect = 9e-31,   Method: Compositional matrix adjust.
 Identities = 71/219 (32%), Positives = 120/219 (54%), Gaps = 2/219 (0%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           M E +       VR+IMIP+  +  ++ +  +      IIE  +SR P+  ++ D+I GI
Sbjct: 147 MTEAISSFDKLIVREIMIPKVDIFAIQEDTPIRNAFPAIIEEGYSRIPLYKKNIDNITGI 206

Query: 117 LMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           L+ KDLL   +S   +  +  V +  +  PE K+V  +L+EFR +  H+AIV++E+G   
Sbjct: 207 LLVKDLLANPQSANSSQPVSSVAKSPIYAPEIKKVSSLLQEFRQKHRHLAIVVNEYGVTE 266

Query: 177 GLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE- 235
           G++++EDI+E I GEI DEYD ++DI ++++  ++W V    +I D  E F      E  
Sbjct: 267 GIISMEDIIEEIFGEIADEYDVQEDIPYKKVG-NSWIVDGRMNISDAEEYFNLKIHHENS 325

Query: 236 VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
            DT+GG V    G +P +G  I  + +  ++     R +
Sbjct: 326 YDTLGGHVFHKVGAVPQKGMKIHHENFDIEIITCSERSV 364


>UniRef50_C7NDD7 CBS domain containing protein n=3 Tax=Leptotrichia
           RepID=C7NDD7_LEPBD
          Length = 427

 Score =  136 bits (342), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 75/250 (30%), Positives = 139/250 (55%), Gaps = 2/250 (0%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
             DE+L  ++   ++ + +E   +M+  + + ++  V++I+ PR  +  L+    +D+  
Sbjct: 172 TEDEILTFLKAGTESGVFEEGEEEMITSIFEFSETTVKEILTPRRDVFALEAESKIDDVW 231

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
           + I++   +R P+ +E  D I G +  KDLL + +   E   +   +++A  VP +K + 
Sbjct: 232 NEILDQGFTRIPIYTETIDKIVGTVHMKDLLRYDKQTGENPPIKDFMKEAYFVPITKPLV 291

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+EF+ ++ HMAIVIDE+GG  G+VTIED+LE IVGEI DE+D+E++ + +Q+    +
Sbjct: 292 ELLEEFKLKQLHMAIVIDEYGGTQGIVTIEDLLEEIVGEIRDEFDQEEE-NIQQIREKIF 350

Query: 213 TVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
            ++    IE+ N+         EE DTI G +    G +    + +  D +  KV   D+
Sbjct: 351 DIKGDTPIEEINDKLEIEIPLSEEYDTISGYIQDKLGKVADVFDQVKGDNFVLKVTDVDN 410

Query: 272 RRIIQVHVKI 281
           +R+ +V   I
Sbjct: 411 KRVERVRAVI 420


>UniRef50_Q0EWJ5 CBS:Transporter-associated region n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0EWJ5_9PROT
          Length = 276

 Score =  136 bits (342), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 88/263 (33%), Positives = 150/263 (57%), Gaps = 10/263 (3%)

Query: 20  SLLLSQLFHGEPKNRDELLALIRDSGQNDLI-DEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
           SLL+  L  G  ++  ELL ++   G+   +  E  R+MLE ++   D RVR++M+PRS 
Sbjct: 14  SLLIDSLRPG--RDEQELLTIL---GRAVAVQSEGQRNMLEAIVHFHDTRVREVMVPRSD 68

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           +  +  +  L E    +IE   SR PVI  D DH+ G++  +D++     + ++  + ++
Sbjct: 69  IEAVAADTPLAEVQRSMIELGVSRMPVIDGDIDHVLGMVHVQDIMQ-AGLNGKSPVLAEL 127

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI-EDEYD 197
           LR  + V E ++V  +L E R     +AIV+DEFGG +GLVT+ D++  I+GE+ ED  D
Sbjct: 128 LRPCLKVLELEQVSGLLSEMREHACRIAIVLDEFGGTAGLVTLSDLVREIIGEVGEDGQD 187

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
           EE +   + L   ++ V A   IE+  EA G+   + + DT+ G ++   G +P  GE++
Sbjct: 188 EEQEC--KALPDGSFQVLARMHIEELAEAVGSPLPEGDYDTVAGWLITRLGRIPHVGESV 245

Query: 258 DIDGYQFKVAMADSRRIIQVHVK 280
            +DG++  +  AD RRI +V ++
Sbjct: 246 KLDGFRIHIVEADPRRISKVRMQ 268


>UniRef50_A7VCA4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VCA4_9CLOT
          Length = 433

 Score =  136 bits (342), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 80/258 (31%), Positives = 144/258 (55%), Gaps = 4/258 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           DEL+ ++  S +  +I+   ++M+  V+D  D RVRDIMIPR+ +  +    T DE L  
Sbjct: 173 DELITMVNVSEEEGVIENKEKEMITNVVDFGDSRVRDIMIPRTDVTMVPVTATYDELLKQ 232

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS-DAEAFSMDKVLRQAVVVPESKRVDR 153
            +E  ++R PV  + +D++ GIL  KDL  +  + D   F +  ++R+   V E ++ + 
Sbjct: 233 YMEVPYTRLPVYKDSRDNVIGILHVKDLFFYKATHDINNFDVTNIVREPFYVYEFQKTND 292

Query: 154 MLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWT 213
           +L   +S    + IV+DE+G   GL+++ED++E I+G+I+DEYD+ +  +  ++    ++
Sbjct: 293 LLANMKSSSNSIGIVLDEYGVCVGLISMEDLIEEIIGDIKDEYDDAEHNNIVKIDDTHYS 352

Query: 214 VRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
           +     ++D N+A       E+ D+IGG ++Q   HLP+ G+T        KV   D  R
Sbjct: 353 IDGGIKLDDLNDALDLDIESEDYDSIGGYIIQLLDHLPSVGDTASDGVISCKVTKLDKNR 412

Query: 274 IIQVHVKIPDDSPQPKLD 291
           + +V ++I    P+P  D
Sbjct: 413 VSRVLLEIL---PKPNTD 427


>UniRef50_C4GB29 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
           DSM 14600 RepID=C4GB29_9FIRM
          Length = 290

 Score =  135 bits (341), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 84/283 (29%), Positives = 158/283 (55%), Gaps = 24/283 (8%)

Query: 13  SNKKGFFSLLLSQLFH-----GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           S+K  FFS    +LFH      E +  ++L++ IR+  +  ++      M+  +   AD+
Sbjct: 6   SSKNKFFS----RLFHRDEALSEDEFEEDLISKIREGHEQGVLSAREVTMIRNIFAFADK 61

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
            V+DIM  RS ++ +    T+ E ++ +IE+ +SR+PV  ++ D+I G++  KD L ++ 
Sbjct: 62  DVKDIMQHRSNIVAIDGESTMQEAVEQMIENHYSRYPVYIKNLDNIIGLVHIKDTLRYV- 120

Query: 128 SDAEAFSM-------DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
             AE   M       + ++R+ + VP++  +D +L + + ++ HM +V DE+G   GL++
Sbjct: 121 --AEGHDMSVKLRDLEYMVRRVIFVPQTHSIDTLLAQMQHRKNHMILVQDEYGQTCGLLS 178

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           +ED++E IVG I+DEYD+ED++  R L    + ++    ++   +  G   SDEE +T+ 
Sbjct: 179 MEDVIEEIVGNIQDEYDDEDELVAR-LGDGAYMMQGSTPLDTVADTLGIDLSDEEAETLN 237

Query: 241 GLVMQAFGHLPARGETIDID--GYQFKVAMADSRRIIQVHVKI 281
           G +++  G +P   E+ D+   GY F V   D   ++ + V+I
Sbjct: 238 GFLLEKLGRIPQDHESFDVTARGYHFHV--IDVEHMVALGVRI 278


>UniRef50_A4J4V5 Putative uncharacterized protein n=1 Tax=Desulfotomaculum reducens
           MI-1 RepID=A4J4V5_DESRM
          Length = 445

 Score =  135 bits (341), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 82/251 (32%), Positives = 134/251 (53%), Gaps = 5/251 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H +  + +E+  ++  S +   I +    +    +  AD+   +IM+PR  M+ L  N +
Sbjct: 175 HHQIHSEEEIRMILLQSHKGGEITQTELQLARNSLHFADRVAAEIMVPRPDMVCLYTNLS 234

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD----KVLRQAV 143
            +E L +I E  ++R+PV   DKD+I G +  KDL     +D    +++    + LR+A+
Sbjct: 235 WEENLKIITEEKYARYPVCDGDKDYIIGFVNTKDLCFSGLTDLNMLNLEGFLKQALRKAM 294

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
           VV E   +D +LK+ +  R  MAIV DE+GG +GL+T+EDILE IVGEI+DE+DEE  + 
Sbjct: 295 VVTELTPIDEILKKMQKNRLQMAIVQDEYGGTAGLLTLEDILEEIVGEIQDEHDEERQL- 353

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
              L  + +++ A   I DFN  F      + V T+ G   +     P +G+T+     Q
Sbjct: 354 IESLGGNRYSLDARLPIADFNLEFDLDLKAKGVYTLAGWFQEESHRTPEKGQTVRYKNLQ 413

Query: 264 FKVAMADSRRI 274
           F ++  D   I
Sbjct: 414 FSISEIDKNTI 424


>UniRef50_C3L2Y2 Transporter, HlyC/CorC family n=26 Tax=Bacteria RepID=C3L2Y2_CLOB6
          Length = 447

 Score =  135 bits (341), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 71/234 (30%), Positives = 133/234 (56%), Gaps = 3/234 (1%)

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
           ++M+  + D  +   ++IM PR+ + T+  N +    ++ ++E  +SR P+  ED D+I 
Sbjct: 210 KEMINSIFDFDNTLAKEIMTPRTSVFTMDINDSPKNIINNMLEERYSRVPIYDEDIDNII 269

Query: 115 GILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFG 173
           GIL  KD+L  + + + +   +  +LR    +PE+K +D + KE ++ + ++AI+IDE+G
Sbjct: 270 GILHIKDILSIINKENIKKEDLINILRIPYFIPETKAIDFLFKEMQTSKNYIAILIDEYG 329

Query: 174 GVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD 233
           G SG+VT+ED++E ++G I DEYDE+   +  ++  +T+ + A  +I+D NE        
Sbjct: 330 GFSGIVTMEDLIEEVMGNIFDEYDEDHTEEIIKMDANTFLLDASITIDDLNEKLNLELPS 389

Query: 234 EEVDTIGGLVMQAFGHLPAR--GETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           E  DT+GG ++   G +P       I  +   FK+    + RI ++ + I + S
Sbjct: 390 ENFDTLGGFILDITGTIPKCNVNSEIQYNNLIFKIEKVSNNRIEKIKLYINEKS 443


>UniRef50_Q3ZYX1 Probable hemolysin-related protein n=5 Tax=Dehalococcoides
           RepID=Q3ZYX1_DEHSC
          Length = 424

 Score =  135 bits (341), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 77/271 (28%), Positives = 149/271 (54%), Gaps = 10/271 (3%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLA------LIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           G+ S   ++LF G P  +  L+A      +I    +   ++ED  ++L  V + +D+ VR
Sbjct: 146 GWISSGFTKLFGG-PSLKSSLVAEDDIRAMITVGHKEGTVEEDKAELLHKVFEFSDRPVR 204

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           ++++PR ++ ++++  TL + LD+  ES  SRFPV  E+ D++ GIL  KD+L  +    
Sbjct: 205 EVIVPRPEVESVEKGSTLKDFLDLYAESPMSRFPVYEENMDNVLGILSIKDVLMALAKGT 264

Query: 131 EAF--SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
                S+D ++R A   PE+K + ++  E R + + M +VIDE+GG +G+V++  ++E I
Sbjct: 265 HTPQDSVDDLMRPAYFAPETKPIGKLFNEMREKNFRMCVVIDEYGGTAGIVSLSRLMEEI 324

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VG + DE  + +  D+  ++ +T+ V     IE+ N        + + +TI GL++   G
Sbjct: 325 VGPVGDELADAEK-DYESINEYTFQVDGSMRIEEANVEMDLDLPEGDYETIAGLILDRLG 383

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           ++P +G+ I +   +  +      +I +V +
Sbjct: 384 YIPKQGQQIKLQNLKVVITHMKGMKIDEVLI 414


>UniRef50_Q164J1 CBS domain protein n=37 Tax=Rhodobacterales RepID=Q164J1_ROSDO
          Length = 435

 Score =  135 bits (341), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 74/242 (30%), Positives = 132/242 (54%), Gaps = 10/242 (4%)

Query: 49  LIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISE 108
           +++++ RD + G +D+ ++ V +IM+ RS +  +  +    + L   ++S H+R PV  E
Sbjct: 192 VVEKEHRDRILGALDLNERAVEEIMLHRSGIEMINADDDPQDILHQCLQSNHTRLPVFQE 251

Query: 109 DKDHIEGILMAKDLLPFMR----------SDAEAFSMDKVLRQAVVVPESKRVDRMLKEF 158
             ++I G++ AKDLL  M           S   +F +  V  +   VPE+  +D  +++F
Sbjct: 252 HPENIIGVIHAKDLLRAMYKIIGGPEGDASKLRSFKLSDVAMKPYFVPETSTLDEQMRQF 311

Query: 159 RSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA 218
             +R H A+V+DE+G + GL+T+EDILE IVGEI DE+D  D    +Q     + +    
Sbjct: 312 LRRRTHFALVVDEYGSLQGLITLEDILEEIVGEITDEHDPTDMAPIQQTEDGQFVIDGAM 371

Query: 219 SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVH 278
           +I D N A   +  D+E +T+ GLV+     +P  G+     G++F+V   +  RI ++ 
Sbjct: 372 TIRDLNRAADWNLPDDEANTVAGLVIHEAQMIPTTGQVFSFHGFRFEVCAREGNRITELK 431

Query: 279 VK 280
           ++
Sbjct: 432 IR 433


>UniRef50_B0R9W4 Hemolysin homolog n=3 Tax=cellular organisms RepID=B0R9W4_HALS3
          Length = 459

 Score =  135 bits (341), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 93/263 (35%), Positives = 137/263 (52%), Gaps = 16/263 (6%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H EP    E+L+++ ++     I      M+E V  + D  VR+IM PR  + ++  +  
Sbjct: 205 HTEP----EILSVLSEASAAGRISPAEVSMIEHVFSLDDTTVREIMRPRPDVTSVSADTP 260

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQ----AV 143
           L E   +     ++R+PV     D + G +  KD+L    SDA   S D   R+     V
Sbjct: 261 LPELRTMAASGEYTRYPVTEGPDDDVIGFVDVKDIL--RASDAIDESGDVTARELSRPVV 318

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD---EED 200
           VVPE+ RVD +L EF+++   MA+VIDE+G   GL TIED LE+IVG+I D++D      
Sbjct: 319 VVPETLRVDELLAEFQAEHRQMAVVIDEWGAFEGLATIEDALEVIVGDIRDQFDLATHAQ 378

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
            I+ R      + V    SI + N+  GT F +E V+T+ GLV+   GH P  G+   ID
Sbjct: 379 SIEPRD--DGGYEVPGAVSITELNDHLGTDFENEAVETVAGLVVSRLGHAPTVGDRAVID 436

Query: 261 GYQFKVAMADSRRIIQVHVKIPD 283
            + F+V   D  RI  + V  PD
Sbjct: 437 THTFRVTGVDGARITSLTVT-PD 458


>UniRef50_B3QWB4 Transporter-associated region n=1 Tax=Chloroherpeton thalassium
           ATCC 35110 RepID=B3QWB4_CHLT3
          Length = 411

 Score =  135 bits (340), Expect = 1e-30,   Method: Compositional matrix adjust.
 Identities = 89/286 (31%), Positives = 150/286 (52%), Gaps = 27/286 (9%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIR--DSGQNDL-----------------IDEDTRDMLE 59
           FS+L S L         + +AL R    GQND                  ++    +++ 
Sbjct: 133 FSILFSPLIATIHFFSSQAVALFRLLSKGQNDHTSALDYRILHRIYTPKEVERKDSEIVS 192

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
            +  I+D +VR+ MIPR+ +  +    TLDE + V  ++ +S  PV     DHI G++  
Sbjct: 193 NIFAISDVQVRESMIPRTDIHAVPSTITLDELVKVFGKTKYSVVPVYESTIDHIIGVVSV 252

Query: 120 KDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
            +L  F + D    S+  VLR+A+ VPE+K+   +L+EF     +MAIV+DEFGG +GLV
Sbjct: 253 YEL--FKKPD----SLKSVLREALFVPETKKTVELLQEFCYSDMNMAIVVDEFGGTAGLV 306

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDT 238
           T ED++E ++G++ ++   +D+I    LS +T+ V     I+  NE     FS +E+ +T
Sbjct: 307 TSEDLIEELIGDVHNDCQSDDEIC-HALSENTFLVSGRVDIDTINEKLKLGFSVEEQYET 365

Query: 239 IGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           + G ++   G +P +GE   I+   F +A A   +I+ V +++ D 
Sbjct: 366 LAGYILSHIGRIPKQGEIFKIENKVFTIARASKTKIVLVKLQLVDS 411


>UniRef50_C9RLZ8 CBS domain containing protein n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RLZ8_FIBSS
          Length = 441

 Score =  135 bits (340), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 89/262 (33%), Positives = 138/262 (52%), Gaps = 14/262 (5%)

Query: 42  RDSGQNDL----------IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
           RD+ Q DL          ++++ R M+  + D  +  VR+IM PR  M  +  + +L++ 
Sbjct: 173 RDAVQADLSDSSLSEGEGLEKEERQMILNIFDFVETPVREIMTPRVDMCAIDVDTSLEDL 232

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLP-FMRSDAEAFSMDKVLRQAVVVPESKR 150
           + V+    HSR PV  E  D+I GIL  +D L  +     E F + K++   V VP  K+
Sbjct: 233 VKVLNNERHSRLPVYKETVDNIVGILSNRDFLEWYTEHHEEPFDLMKLVMPPVYVPYHKK 292

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH 210
           +D +L E R     +AIV+DE+GG +GLVT+EDILE IVGEI DE D ++D D ++L   
Sbjct: 293 IDDLLTELRKTGNQLAIVVDEYGGTAGLVTLEDILEEIVGEIRDEDDMDEDEDVQKLKDG 352

Query: 211 TWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
            + +  L ++ D            E   V+T+ GL+    G +P+ G  + I GY F+V 
Sbjct: 353 RYILDPLMTLSDLEYELDVELKPPENSHVETLSGLIQATLGIIPSPGAEVKIQGYTFRVL 412

Query: 268 MADSRRIIQVHVKIPDDSPQPK 289
             D  R+ +V + +P     PK
Sbjct: 413 RMDGTRMEKVMMILPAGVKGPK 434


>UniRef50_C7RN87 Putative uncharacterized protein n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RN87_9PROT
          Length = 480

 Score =  135 bits (340), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 89/290 (30%), Positives = 150/290 (51%), Gaps = 31/290 (10%)

Query: 28  HGEPK---NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKR 84
           HGE     + +E+  ++  S ++  +D +   M+ GV  + +  VR+ M+PR+++  L +
Sbjct: 186 HGESHFTMSVEEIRMILSASEKDGTLDPEETQMIRGVFKLDEHTVREAMVPRTRIRALTQ 245

Query: 85  NQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAV- 143
             TL + L V  +  H+RFPV  +  D I G++  K+LL  M +++   ++++V R+ V 
Sbjct: 246 EDTLADALRVFRDVPHARFPVCDKSLDRITGVVAIKELLTVM-AESSGQTLEEVSRRPVG 304

Query: 144 -------VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
                  +VP SK +  +LKEF+  R  MAIVIDE+GG  G++T+EDILE IVGE EDE+
Sbjct: 305 EFAQAPFIVPNSKSLSDLLKEFKHTRQQMAIVIDEYGGTEGIITLEDILEEIVGEYEDEF 364

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF-SDEEVDTIGGLVMQAFGHLPARGE 255
             +     ++L    + + A   + D        F +D++  T+ GL  +  G +P  G+
Sbjct: 365 TRQAR-RVKKLVGSQYEIDASMRVSDLETLIDFPFPTDDDYVTLAGLFYKKLGSVPKVGD 423

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVK-----------------IPDDSPQP 288
           T+ ++G Q  V   D+ RI  +  +                  PD SP P
Sbjct: 424 TVKLEGGQLTVLEMDNHRITLLRFEDTAVGEDGVIRLVENSSAPDASPAP 473


>UniRef50_C1XJH4 CBS domain-containing protein n=1 Tax=Meiothermus ruber DSM 1279
           RepID=C1XJH4_MEIRU
          Length = 458

 Score =  135 bits (340), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 94/276 (34%), Positives = 155/276 (56%), Gaps = 6/276 (2%)

Query: 14  NKKGFFSLLLSQL----FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           N+ G F L L  L     H    + +EL  ++  S +  ++DE   +++  ++D+ +  V
Sbjct: 167 NRSGNFFLRLMGLKEAPSHSMVGSAEELKLIVEASSKEGVLDESEGEIISQILDLEETLV 226

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           R IM+PR +M+T+    +L +   +  E  +SR PV  E  D+I G+   KDLL +   +
Sbjct: 227 RSIMVPRVEMVTISAEASLRDFWAMAREHRYSRVPVYQETIDNIIGVAYIKDLLEYSGPE 286

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            ++  +  +   A  VPE+     +L+E R ++ HMAIV+DEF G +GLVT+EDI+E I+
Sbjct: 287 LDSIKVGSICHPAYFVPETMGARELLREMRRRKTHMAIVVDEFKGTAGLVTLEDIIEEII 346

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           GEI DE DEE+    +Q++   + + A   +E+ ++  G    + E DT+ G +M  FGH
Sbjct: 347 GEIYDESDEEEVAPVQQIAEGVYLLDASVPLEEASKKLGIELPEGEYDTLSGFLMNEFGH 406

Query: 250 LPARGETIDIDGYQFKVAMADSRRI--IQVHVKIPD 283
           +P  GE ++  GY+F V  AD R I  ++   KIP+
Sbjct: 407 IPEVGEKLEYGGYEFIVETADPRGIERVRAQNKIPE 442


>UniRef50_C7R522 CBS domain containing protein n=1 Tax=Jonesia denitrificans DSM
           20603 RepID=C7R522_JONDD
          Length = 441

 Score =  135 bits (340), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 74/204 (36%), Positives = 115/204 (56%), Gaps = 3/204 (1%)

Query: 63  DIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL 122
           D+ D  +R +M+PR+ MIT+ R   LD+   + I S  SR PVI +  D + G+L  KD+
Sbjct: 190 DLRDTPIRAVMVPRTDMITVARTAPLDKAQKLFIRSGFSRLPVIGDSSDDVHGVLYFKDV 249

Query: 123 LPFMRSDAEAF--SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
              + +   A   +    +R    VPES   D +L+  +S+R H+A+V+DE+GG++GLVT
Sbjct: 250 ARVLLTSPHASVRTAQDTMRPVWFVPESTHADDVLRSMQSKRAHIAMVVDEYGGIAGLVT 309

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
            EDILE IVGE+ DE+D         L++    V A  ++++ +E      +D++VDTI 
Sbjct: 310 AEDILEEIVGELTDEHDST-PTTVDTLNQGVLRVPARMTLDELSEYLHRPITDDDVDTIA 368

Query: 241 GLVMQAFGHLPARGETIDIDGYQF 264
           GL+ +A G LP       I+G   
Sbjct: 369 GLLTKALGKLPIAQSQATINGLHL 392


>UniRef50_B0NK60 Putative uncharacterized protein n=1 Tax=Clostridium scindens ATCC
           35704 RepID=B0NK60_EUBSP
          Length = 413

 Score =  135 bits (339), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 85/270 (31%), Positives = 147/270 (54%), Gaps = 10/270 (3%)

Query: 17  GFFSLLLSQLFHGE---PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           G +  LLS LF          +ELL ++ ++ Q+  IDE    ++   ++  +Q V D++
Sbjct: 146 GQWKKLLSLLFKSSDDTGITEEELLFIVDEAEQDGGIDEQESKLIHSALEFTEQEVIDVL 205

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR  +  +    T +E  ++  E+A+SR P+  E  DHI GI+  KD   ++    +  
Sbjct: 206 TPRIDITAVSTQATKEEIAEIFAETAYSRIPLYDESVDHIIGIIYQKDFHNYVYHTDKDI 265

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           S  +++R  + V ++K++  +LKE + ++ H A+V+DEFGG  G+VT+EDILE +VGEI 
Sbjct: 266 S--EIVRPTLYVHKNKKIGVLLKELQQRKMHFAVVLDEFGGTIGIVTLEDILEELVGEIW 323

Query: 194 DEYDE-EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTI-GGLVMQAFGHL 250
           DE+DE   +I+ +  S         A++E   E      + DEE+  I  G VM+    +
Sbjct: 324 DEHDEVNSEIEIK--SEDEVIALGSANVEKLFEVLNIEITEDEEIPVIVNGWVMKELERI 381

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVK 280
           P +G+T +  GY+  V   + +R+ +V +K
Sbjct: 382 PVKGDTFEYKGYKITVLSVNEKRVEKVLIK 411


>UniRef50_B0PAE4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0PAE4_9FIRM
          Length = 472

 Score =  135 bits (339), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 86/275 (31%), Positives = 150/275 (54%), Gaps = 10/275 (3%)

Query: 22  LLSQLFHG------EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           LLS+LF        E    +E+  ++    +   I++  +DM+  + +  D+ V ++M  
Sbjct: 196 LLSRLFGARGGDETERVTEEEIRMMVDVGNEKGAIEQSEKDMINNIFEFDDRNVSEVMTH 255

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R+ M  + ++ T+D  + + IE+  SR PV  ED D I GI+  KDLL  + +    F  
Sbjct: 256 RTDMTAVPKDVTIDRIVAIAIETGFSRIPVYDEDIDDIMGIVYVKDLLCLIGTPGVDFDA 315

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
            K +R A+ VPES     +  +F+ ++  +AIV+DE+GG +G+ ++ED+LE IVG I+DE
Sbjct: 316 QKYMRPALFVPESMSCVDLFAQFKQKKVMVAIVVDEYGGTAGIASMEDLLESIVGNIQDE 375

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF-SDEEVDTIGGLVMQAFGHLPARG 254
             +++D +  ++S   +T+    SIED    F      D E DTIGGL+++    +P+  
Sbjct: 376 -YDDEDEEICKMSDGVYTLDGAVSIEDVERLFDIELDEDSEYDTIGGLLIEKLERIPSPH 434

Query: 255 E--TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           E   +++ G +F V + + RRI ++  + P    Q
Sbjct: 435 EHPALELSGVRFTVLLVEDRRIARIRAEKPSAPGQ 469


>UniRef50_UPI00016C05A3 CBS/transporter-associated domain protein n=1 Tax=Epulopiscium sp.
           'N.t. morphotype B' RepID=UPI00016C05A3
          Length = 282

 Score =  135 bits (339), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 70/253 (27%), Positives = 144/253 (56%), Gaps = 7/253 (2%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + + +L LI +  +  +ID  +++M+EG++D   +   ++M PR +++ +  ++ +DE +
Sbjct: 26  SEESILRLIDEGSKEGIIDVTSKEMIEGILDFHGKNANEVMTPRPEIVAIDISKDIDEII 85

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM---RSDAEAFSMDKVLRQAVVVPESK 149
           D ++E++ +R PV   D   + G+L  +  L  +   + + +A  ++ VL +  +VPE+K
Sbjct: 86  DFVLETSFARLPVYEGDVHKVIGVLHVQTFLGHLYKCQRELKAVILEDVLDKPYIVPEAK 145

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            + ++LKE ++++ HMAI+ DE+G VSG+VT+ DI+  I+G+I+D  D+ +D        
Sbjct: 146 NIKKLLKEMQAEKKHMAIICDEYGDVSGIVTLNDIMLEIIGDIQD--DDSEDTAITLQDD 203

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
            ++ V  LA ++D N+        E  DT+ G V+   G +P     ++ +G  F++   
Sbjct: 204 GSYLVDGLAHLDDINKRLNIDLECEHYDTVSGFVIHLLGEIPKDLVKVNYNGITFEIKNI 263

Query: 270 DSRRI--IQVHVK 280
              R+  +Q++ K
Sbjct: 264 KGNRVEKLQIYKK 276


>UniRef50_Q041Z4 Hemolysin-like protein with CBS domains n=27 Tax=Lactobacillus
           RepID=Q041Z4_LACGA
          Length = 288

 Score =  135 bits (339), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 72/231 (31%), Positives = 130/231 (56%), Gaps = 5/231 (2%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           M+EG+++  ++  R++M+PR+    +  N    E LD I++  +SR PV   DKD I G+
Sbjct: 50  MMEGILEFEEKMAREVMVPRTDAFMVDINDNFQENLDQILKEPYSRVPVYDGDKDKIVGV 109

Query: 117 LMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGV 175
           +  + +L    +   +    D+V+ + +  PE+  +  +L E +  +  +AI+ DE+GGV
Sbjct: 110 IHIRTVLRKAHKIGFDKLDYDQVMFKPLFAPETIELGELLVEMQQTQRQLAILTDEYGGV 169

Query: 176 SGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE 235
            GL TIED++E IVG+I+DE D+  ++ F ++    + +     + DFNE FGT  + E+
Sbjct: 170 VGLTTIEDLIEEIVGDIDDEVDKA-EVLFSKIGPREYVIYGKMPLADFNEEFGTDLAMED 228

Query: 236 VDTIGGLVMQAFGHLPARGETIDI---DGYQFKVAMADSRRIIQVHVKIPD 283
           VDT+ G V+   G +PA+GE + +   +G           R++ + + IP+
Sbjct: 229 VDTVAGYVITKLGMIPAKGEKLSVKLDNGMILTTRRMKGSRLLTLLLTIPE 279


>UniRef50_C7HS55 Transporter n=3 Tax=Anaerococcus RepID=C7HS55_9FIRM
          Length = 406

 Score =  135 bits (339), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 87/274 (31%), Positives = 142/274 (51%), Gaps = 7/274 (2%)

Query: 17  GFFSLLLSQLFHGEPKNRDEL----LALIRDSGQ-NDLIDEDTRDMLEGVMDIADQRVRD 71
           G F+  L++       N D++    L  I D G+   +I+ +  +++  V D A     D
Sbjct: 135 GLFTKYLTKKLSDGADNSDKVTEEDLKTIVDVGEEQGVINNEESEIINNVFDFAGSFASD 194

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM PR+ M  +  + T +E    +IES HSR PV  E  D+I G+L  KD++ F+    E
Sbjct: 195 IMTPRTNMEAIAIDSTKEELDKFLIESKHSRIPVYGESIDNIVGVLHMKDIVTFVAEGRE 254

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  +LRQ     E+  +  + K  +     +AIV+DE+GG  GLV+IEDI+E +VG+
Sbjct: 255 P-RLKDMLRQTYYAYENMNIIDLFKSMKKMNVSLAIVVDEYGGTEGLVSIEDIIEELVGD 313

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DEYD +D+  ++ +S + + V A   I DFN+ F     + + D++GGLV+     LP
Sbjct: 314 IYDEYDPDDEKVYK-VSDNEFIVDASMHINDFNDYFNRDIKEVKNDSVGGLVIDYLNRLP 372

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
             G+ + +D         +  +I  + VK   +S
Sbjct: 373 KTGDIVKVDDVTLICEKVERYKINLLRVKFDSES 406


>UniRef50_B6FYX0 Putative uncharacterized protein n=1 Tax=Clostridium hiranonis DSM
           13275 RepID=B6FYX0_9CLOT
          Length = 446

 Score =  134 bits (338), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 86/249 (34%), Positives = 140/249 (56%), Gaps = 19/249 (7%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           I+ D ++ ++ V D +D  VR+IM  +S+++ +  + +L E  + I E+ +SR+PV  E+
Sbjct: 199 INSDEKEWIDNVFDFSDSSVREIMTHKSEVVGIYTDDSLMEIEEKIHETGYSRYPVYGEN 258

Query: 110 KDHIEGILMAKDLLP-----FMRSD---------AEAFSMDKVLRQAVVVPESKRVDRML 155
            + I+GIL AKD        F + D          E   MD  LR+   +P+S     + 
Sbjct: 259 DNDIKGILYAKDFFAEVYNCFAKEDDDLGVVVNKNELNIMDN-LRKPYFIPDSMSSLLLF 317

Query: 156 KEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVR 215
           K  +    H+AIVI+E+G   GL+T+ED+LE IVG I DEYDE DD D + +S  TW ++
Sbjct: 318 KNMQKNNTHIAIVINEYGENIGLITMEDLLEEIVGNIYDEYDECDDGDVK-ISETTWKIK 376

Query: 216 ALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDID--GYQFKVAMADSR 272
              S++D ++ F   F D+ + DTI GL++     +P  GE  +I+  G + KV   ++R
Sbjct: 377 GSTSLDDLSDKFDIDFPDDLDYDTISGLILAKIQRIPNDGEKFEIEAFGMKIKVEKVEAR 436

Query: 273 RIIQVHVKI 281
           +I +V + I
Sbjct: 437 KIEEVIITI 445


>UniRef50_B0MCI7 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0MCI7_9FIRM
          Length = 318

 Score =  134 bits (338), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 76/252 (30%), Positives = 140/252 (55%), Gaps = 11/252 (4%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E++ ++    +   I ED   M+  + +  D+ V D+M  R ++  +    +L+E L  
Sbjct: 58  EEIMNIVNQGHEQGAILEDEAKMITNIFEFGDKDVTDVMTSRKKIDGIDCTMSLEEALHF 117

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
           +++  +SRFP+  ED DHI G+L  KD++    ++ +   + ++ R+   V ++  +  +
Sbjct: 118 MLDEPYSRFPLYEEDIDHIIGVLYLKDVIDAYINNKD-LELYEIAREPFYVHQTMNLSVL 176

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWT- 213
            +E ++++ HMAIV+DE+    G+V++ED+LE+IVG I DEYD ED    R++++  W  
Sbjct: 177 FQEMQTKKIHMAIVVDEYSQTEGIVSMEDMLEVIVGNILDEYDVED----REITKLGWAD 232

Query: 214 ---VRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI--DGYQFKVAM 268
              +R    +E   E     F  EE++T+ G ++   GHLP +GE ++I  +G+ FK   
Sbjct: 233 IFLMRGSTRLEKIEEVLDIEFDVEEIETLSGFLVDQLGHLPEQGEEVEIIYEGWSFKSVD 292

Query: 269 ADSRRIIQVHVK 280
                I QV V+
Sbjct: 293 IHDNVIKQVKVE 304


>UniRef50_A2SSZ1 Putative uncharacterized protein n=1 Tax=Methanocorpusculum
           labreanum Z RepID=A2SSZ1_METLZ
          Length = 420

 Score =  134 bits (338), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 91/282 (32%), Positives = 143/282 (50%), Gaps = 12/282 (4%)

Query: 18  FFSLLLSQLF----------HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           F ++LLS LF          H      +E+   I        I+E+ ++M+  V+   D 
Sbjct: 130 FLTMLLSPLFYVYDRFRKKDHSPSVTEEEIREWIDVGEMEGAIEEEEKEMIYSVLKFNDT 189

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
             ++IM PR  +  ++   TL+E +    E+  SR PV  +  D+I G L  KDL     
Sbjct: 190 TAKEIMTPRPDVAVVEDTVTLEEAVSHFRETGFSRVPVYHDKTDNIVGTLNFKDLFNAYS 249

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
           +D    S+  ++     VPESK++D +L+E + +R HMAIV+DEFGG SG+VT EDILE 
Sbjct: 250 TDNRKASVKSLMLDVYCVPESKKIDVLLRELQVRRVHMAIVLDEFGGFSGVVTFEDILEE 309

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE--EVDTIGGLVMQ 245
           +VG+I DE D ++  D   +    + + A   +   NE F     ++    +TIGGLV  
Sbjct: 310 LVGDIMDESDGDEVSDIIPIGDGLYMIDAQVRVALLNERFDISLPEDPGNYETIGGLVFS 369

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             GH+P  GE+I + G    + +   R    + VK+   +P+
Sbjct: 370 QLGHIPRLGESIPLPGDHITLVVTKMRGRQILKVKMILAAPE 411


>UniRef50_Q2NIR0 Hymolysin-related protein n=5 Tax=Candidatus Phytoplasma
           RepID=Q2NIR0_AYWBP
          Length = 423

 Score =  134 bits (338), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 71/250 (28%), Positives = 138/250 (55%), Gaps = 6/250 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           DEL  ++  S Q  +ID+D   M++ + +     + ++M  R++++ +    T  E +  
Sbjct: 168 DELRLMLISSYQKGIIDKDENKMIQNIFEFDHTNIFEVMRHRTEVVAIDVEITKKELIKT 227

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--EAFSMDKVLRQAVVVPESKRVD 152
           I    ++RFPV     D+I GIL  KD+  ++ S    + F + K +R+  +V +++   
Sbjct: 228 IQNEKYTRFPVYENSIDNIIGILHIKDIFNYLMSSNTNKIFDLKKFIRKPYLVQDAQNTR 287

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            + +E +  + HMAIVIDE+GG +G++T ED++E I+GEI DEYD E ++  ++++++ +
Sbjct: 288 EIFREMKKNKTHMAIVIDEYGGTAGIITFEDLIEEILGEISDEYDNE-ELMIKEVAKNEY 346

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET---IDIDGYQFKVAMA 269
            V   A +E+  E     F+ E+ DT+ G ++   G  P + +    I    ++FK+   
Sbjct: 347 IVNGFADLEEVAETIKLEFNTEDYDTLSGFLIGKLGRCPNQNDKNTEIIYKNFKFKILKH 406

Query: 270 DSRRIIQVHV 279
           + + I Q+ +
Sbjct: 407 NDKVISQIKI 416


>UniRef50_C1D3R1 Putative hemolysin; putative membrane protein n=1 Tax=Deinococcus
           deserti VCD115 RepID=C1D3R1_DEIDV
          Length = 437

 Score =  134 bits (337), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 85/280 (30%), Positives = 146/280 (52%), Gaps = 15/280 (5%)

Query: 11  TISNKKGFFSLLLSQL----FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           ++ N   FF +   +L     H    + +EL  L R S +  LID   R+M+ GV+++ D
Sbjct: 153 SLFNGTAFFLMRALKLQVDHSHAHVHSPEELEDLYRQSARGGLIDASERNMVAGVLNVED 212

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
           + VR+IM PR++++ +  + T+ E L  +  + ++RFPV  +  D + GI+  + L  F+
Sbjct: 213 RVVREIMTPRTKLVVVPGHLTVREALARLANTPYTRFPVSGDTPDDVTGIIHLRQL--FL 270

Query: 127 RSDAEAFSM-DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDIL 185
             +++   +   V R  ++V ES  V  + +  R    H AI +DE+GGV+G+ T+ED L
Sbjct: 271 AGESQPGRLVSDVARPPLIVAESMPVPELWRRLREASRHAAIAVDEYGGVAGMATLEDAL 330

Query: 186 ELIVGEIEDEYDEEDD---IDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGL 242
           E I GE++DE+D E+D   +D  ++      VR    I+  N+ F      +EVDT+ GL
Sbjct: 331 EEIFGEMQDEFDHEEDPITVDGDRV-----LVRGDVLIDLLNDRFELDLPTDEVDTVSGL 385

Query: 243 VMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           +    G LP  G+   +     +V   D R + +    +P
Sbjct: 386 MWHELGRLPMVGDEAGVRNLTLRVEAMDRRAVQRASFILP 425


>UniRef50_C9KJP9 CBS domain protein n=3 Tax=Veillonellaceae RepID=C9KJP9_9FIRM
          Length = 458

 Score =  134 bits (337), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 93/275 (33%), Positives = 142/275 (51%), Gaps = 11/275 (4%)

Query: 12  ISNKKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           +S   G   LLL    H E     DE+  LI    ++   ++  + M++ +  ++DQ   
Sbjct: 166 LSGSAGGVLLLLGINPHVEDTVTEDEVKDLIEQGTEDGTFEKSEQAMVDRIFHMSDQTAY 225

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
            +M PR+QM+ L    +L   L +I E   + FPV  E+ D   G+L AKDLL    +  
Sbjct: 226 SLMTPRTQMLWLDLTDSLRHNLRIIREHPQNVFPVGRENLDDFCGVLYAKDLL---NASL 282

Query: 131 EAFSMD--KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           E  S+D  + +R+ + VP S    R+L +FR    H A+V+DE+GGV G +T+ DIL+ I
Sbjct: 283 ERKSLDLAQYIRKPMFVPRSMETFRVLAKFRDTGIHEAMVLDEYGGVVGFITLNDILQEI 342

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG-THFSDEEVD---TIGGLVM 244
           +G+      E D I F     H+W V  L SI+DF E F      DE+ D   T+GG + 
Sbjct: 343 IGDSMSNV-EPDPIQFTPRDEHSWYVDGLCSIDDFKERFDIAELPDEDHDHYQTMGGFLT 401

Query: 245 QAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
             FG++P   E  + +G+ F+V   D  RI ++ V
Sbjct: 402 SYFGYIPKVAEKCEWNGFTFEVVDMDRARIDKILV 436


>UniRef50_C4ZBH2 Hemolysin n=1 Tax=Eubacterium rectale ATCC 33656 RepID=C4ZBH2_EUBR3
          Length = 303

 Score =  134 bits (336), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 75/252 (29%), Positives = 139/252 (55%), Gaps = 7/252 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+++++R+  +   I     +++  V +  D+ V+DIM  R  +++L  + +  + ++ 
Sbjct: 45  EEIISMVREGHEQGTILASEAELIHNVFEFDDKEVKDIMTHRKNIVSLDGSMSFIDAIEF 104

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS----MDKVLRQAVVVPESKR 150
           II++  SRFPV   D D I G+L  KD   F   +    S    +D ++R    +PE+  
Sbjct: 105 IIDTGKSRFPVYENDVDSIIGVLHIKDAFTFFEKNEVYRSSIKDIDGLIRPVDFIPETVN 164

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH 210
           ++ + K+ +S++ H+A+V+DE+G +SGL+ +EDILE +VG IEDE+DEE++   R+    
Sbjct: 165 INDLFKKMQSKKSHLAMVVDEYGQISGLIAMEDILEELVGNIEDEHDEEENY-IRKNDDE 223

Query: 211 TWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE--TIDIDGYQFKVAM 268
           T+ +  +    D  EA      D+  +T+ G ++     +P  G+   I   GY+F V  
Sbjct: 224 TFIMDGMTEFSDVKEALSLPVDDDAYETLNGFIISLSDKIPEEGDKTVISAYGYRFSVMS 283

Query: 269 ADSRRIIQVHVK 280
            + + I QV +K
Sbjct: 284 VEDKVIKQVMIK 295


>UniRef50_Q0G3C6 Putative uncharacterized protein n=2 Tax=Aurantimonadaceae
           RepID=Q0G3C6_9RHIZ
          Length = 444

 Score =  134 bits (336), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 80/238 (33%), Positives = 131/238 (55%), Gaps = 5/238 (2%)

Query: 39  ALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIES 98
           ++I++  Q  +  E  R+MLEGV+ IAD+ VR IM+PR  +  L  + + DE  + II +
Sbjct: 184 SMIKEGTQLGVFKEKEREMLEGVIRIADRNVRSIMVPRPDVDWLSVHDSEDENFEEIIRA 243

Query: 99  AHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEF 158
            HSRFPV+  ++D I GI+  KDL    R +     +   +R+ + V E+  + ++L+ F
Sbjct: 244 GHSRFPVLDTEEDAIVGIVQTKDLFELQRREGR-MDLKTAMRKPLYVNEAMPILKLLEAF 302

Query: 159 RSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA 218
           R    H+A+V+DE+G   G+ T +DIL  I G +  E  EED   FR+    +W V    
Sbjct: 303 RKANLHIAVVLDEYGSFEGIATPQDILTAIAGSL-PEGAEEDVSAFRR-QDGSWLVDGAM 360

Query: 219 SIEDFNEAFGT-HFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
            ++ F     T  F  D + +T+ G V++  GH+P  GE  + + ++ +V   D +RI
Sbjct: 361 PVDAFAYKLKTIEFPEDRDYETVAGFVLEQIGHIPGVGEIFEWENFRVEVVDLDGQRI 418


>UniRef50_Q1J8A0 Magnesium and cobalt efflux protein corC n=129 Tax=Bacilli
           RepID=Q1J8A0_STRPF
          Length = 457

 Score =  133 bits (335), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 77/225 (34%), Positives = 132/225 (58%), Gaps = 4/225 (1%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E   RDE+  ++  S     +D +  +ML+GV  + +   R++M+PR+    +  N    
Sbjct: 192 EQMTRDEIEYMLSKSEAT--LDAEEIEMLQGVFSLDEMMAREVMVPRTDAFMIDINDDPL 249

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPES 148
           E +  I++ + SR PV   DKD I G++  K LL    R   +  +M K+L++ + VPE+
Sbjct: 250 ENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQGFDQINMRKMLQEPLFVPET 309

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             VD +L++ R+ +  MAI++DE+GGV+GLVT+ED+LE IVGEI+DE D+ +     ++ 
Sbjct: 310 IFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLEEIVGEIDDETDKAEQF-VHEIG 368

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
            +T+ V    ++ +FN+ F T    ++VDTI G  +   G +P++
Sbjct: 369 DNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLTGIGTIPSQ 413


>UniRef50_B0MNL0 Putative uncharacterized protein n=1 Tax=Eubacterium siraeum DSM
           15702 RepID=B0MNL0_9FIRM
          Length = 315

 Score =  133 bits (335), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 87/271 (32%), Positives = 140/271 (51%), Gaps = 14/271 (5%)

Query: 15  KKGFFSLLLSQL----FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
            KG   LL   L    +  E   +D +++++    +   +++++  ++  V +  D    
Sbjct: 23  NKGLDKLLSKALGDSYYDKEETTQDNIMSMVDAGNEYGNLEDESAQLINNVFEFGDLVAS 82

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RSD 129
           D+M  R  ++ +  N +LD+ + + +E   SR PV  E+ D I GI++ KDLL  +   +
Sbjct: 83  DVMTHRKNIVGVDVNSSLDDIVYIALEKGFSRIPVYKENIDAIVGIIIVKDLLCLVGNEN 142

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            +   ++  LR+AV VPES     + K   + +  M IVIDE+GG +G++T+EDI+E I+
Sbjct: 143 KDKLKIEDFLREAVYVPESCSCSDVFKFLTNLKSGMGIVIDEYGGTAGIITLEDIIESIM 202

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF-SDEEVDTIGGLVMQAFG 248
           G IEDEYDEE D+   + S   + V   A  ED  E FG     D E DTI G V    G
Sbjct: 203 GNIEDEYDEEKDMIIPR-SNGAYEVSGEADPEDVLELFGYELEEDHEYDTIAGFVTDLLG 261

Query: 249 HLPARGETIDIDGYQFKVAMAD-SRRIIQVH 278
           ++P        +G   KV   D   ++I+VH
Sbjct: 262 YIPEE------EGEHPKVRYKDIIFKVIEVH 286


>UniRef50_Q7NJJ9 Glr1833 protein n=2 Tax=Cyanobacteria RepID=Q7NJJ9_GLOVI
          Length = 432

 Score =  133 bits (335), Expect = 7e-30,   Method: Compositional matrix adjust.
 Identities = 75/229 (32%), Positives = 128/229 (55%), Gaps = 1/229 (0%)

Query: 46  QNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPV 105
           ++  + E  R ++ G + +  + VR +M+PR Q++++  N ++ E   +  +S H+R PV
Sbjct: 192 ESGTVGEQERRIIYGAVALNTRPVRTLMVPRVQLVSISANASIPEARSIAAQSGHTRLPV 251

Query: 106 ISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHM 165
             E  D I GIL AKDLL          ++ ++ R    VP+SK    +L+E + QR H+
Sbjct: 252 YIETIDTIIGILHAKDLLALNPQQEATLAVREIARPVQFVPDSKLAGGLLREMQLQRTHL 311

Query: 166 AIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNE 225
            +V+DE+GG +G+VT+ED+LE IVGEI DEYD E++ ++ +L   +    A  SI   N 
Sbjct: 312 VVVVDEYGGTAGVVTLEDLLEEIVGEIRDEYDAEEETEYERLEDGSGIFLARTSIATVNN 371

Query: 226 AFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
                   +   T+ GL+  A    P  GE +++D ++ ++ + D +RI
Sbjct: 372 VLDFELPRDSALTLRGLMEAALERAPKEGERVEVDRFELEL-LPDGQRI 419


>UniRef50_A8SE58 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=A8SE58_9FIRM
          Length = 434

 Score =  133 bits (335), Expect = 7e-30,   Method: Compositional matrix adjust.
 Identities = 79/259 (30%), Positives = 141/259 (54%), Gaps = 7/259 (2%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           EL+ ++ ++  +  + +   +++   ++  D  V +I+ PR  +I ++ +  L+E     
Sbjct: 169 ELMTMVSEAENDGELTDRESELIRSAIEFDDVEVEEILTPRVDVIAVEDDMPLEEVAQTF 228

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRML 155
            ES +SR PV  +  D+I G++  KD   +M    +   ++ +++  +    S ++ ++L
Sbjct: 229 AESGYSRLPVYHDTIDNIIGVVHEKDF--YMARLKKETKLEDLVKPTLYTTGSTQISQLL 286

Query: 156 KEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVR 215
           +  R Q +HMA+V+DE+GG  G++T+EDILE +VGEI DE+DE  + DFR+ S  +W V 
Sbjct: 287 RTLREQHHHMAVVVDEYGGTEGIITLEDILEELVGEIWDEHDEVTE-DFRKQSDGSWIVL 345

Query: 216 ALASIEDFNEAFGTHFSDEEVD--TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
             A ++D  E  G    DE++D  T+ GLV +    LP  G+   +  Y   V     RR
Sbjct: 346 GSAGVDDLYERLGLP-EDEDIDSNTVNGLVQEKTCRLPKVGDRFTLGSYDGVVTRTAKRR 404

Query: 274 IIQVHVKIPDDSPQPKLDE 292
           + +V +  P + P  K DE
Sbjct: 405 VTEVRLT-PAEKPDTKKDE 422


>UniRef50_C6W2P9 Transporter-associated region n=1 Tax=Dyadobacter fermentans DSM
           18053 RepID=C6W2P9_DYAFD
          Length = 400

 Score =  133 bits (334), Expect = 8e-30,   Method: Compositional matrix adjust.
 Identities = 83/276 (30%), Positives = 141/276 (51%), Gaps = 19/276 (6%)

Query: 18  FFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRD---------MLEGVMDIADQ 67
           F   L++ L+   EP  ++ +L+    S ++D+I  D  D         M    +D  D 
Sbjct: 127 FGEWLMTPLYWVIEPFVKENILS---PSLRDDIISADDPDFDDHSIEERMFINALDFKDL 183

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
           R+RD MIPR ++  +  N T+++     + S HS+  V  E  D + G   A  L     
Sbjct: 184 RIRDCMIPRMEISAVNVNATIEDLRTAFLTSGHSKIIVHKESVDEVLGYCHALSLF---- 239

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
              +   +  ++   ++VPE+     ++  F  +R  +A+V+DEFGG SGLV++ED++E 
Sbjct: 240 --KKPKDISSIITPILIVPEAMPARDLMLRFLEERRSIALVVDEFGGTSGLVSVEDVVEQ 297

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           I GEI+DEYD  +D   RQL  HT+ + A   ++  N+ +G    + + DTI G+++  +
Sbjct: 298 IFGEIQDEYDTTEDWTERQLDEHTYMLSARHELDYLNDKYGWELPEGDYDTIAGMLIHFY 357

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           G LP   E +++  Y F++      RI  V + I D
Sbjct: 358 GDLPDENEVVEMPPYSFQIVSVQDTRIELVKLTIED 393


>UniRef50_A5PBT5 Hemolysin n=1 Tax=Erythrobacter sp. SD-21 RepID=A5PBT5_9SPHN
          Length = 305

 Score =  133 bits (334), Expect = 9e-30,   Method: Compositional matrix adjust.
 Identities = 76/246 (30%), Positives = 131/246 (53%), Gaps = 5/246 (2%)

Query: 43  DSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR 102
           D+G+ DL   + R ML  ++  ++    D+ +PR ++I +    +  E +    E  HSR
Sbjct: 56  DTGKGDLSGVE-RQMLRNLLHFSEHDADDVAVPRGEIIAVNAEASWVEVVATFSEHGHSR 114

Query: 103 FPVISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQ 161
            PV     D + G++  KD+ PF+    A       ++RQ + VP+++    +L + RSQ
Sbjct: 115 MPVYRGQLDDVIGMIHIKDIFPFLAEKKAPPTDWTTLMRQPLYVPQTRNALDVLADMRSQ 174

Query: 162 RYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIE 221
           R H+AIV+DEF G  G++TIED++E IVGEIEDE+D+  +I    +    W   A A ++
Sbjct: 175 RMHLAIVLDEFSGTDGIITIEDLVEEIVGEIEDEHDDAPEIWIASIGEGMWDCDARAELD 234

Query: 222 DFNEAFGTHFS--DEEVDTIGGLVMQAFGHLPARGETID-IDGYQFKVAMADSRRIIQVH 278
           D  E      +  +E VDT+GGL       +P  G+ ++   G++ +V   D   + ++ 
Sbjct: 235 DVAEKIDPRLAEVEESVDTLGGLAFVLAEQVPPVGKVLEHPSGWRIEVTDGDETHVTRLR 294

Query: 279 VKIPDD 284
           +  P++
Sbjct: 295 LHAPEE 300


>UniRef50_C5EUB4 Membrane-anchored CBS domain-containing protein-domain containing
           protein n=5 Tax=cellular organisms RepID=C5EUB4_9FIRM
          Length = 496

 Score =  133 bits (334), Expect = 9e-30,   Method: Compositional matrix adjust.
 Identities = 79/256 (30%), Positives = 143/256 (55%), Gaps = 13/256 (5%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +++++++ +  +  +++ D  +M+  + ++ D+   DIM  R+ M  L  +  L + +  
Sbjct: 189 EDIMSMVNEGHEQGVLEADETEMITNIFELGDKEASDIMTHRTNMTALDGSMLLGDAVHF 248

Query: 95  II-ESAHSRFPVISEDKDHIEGILMAKDLLPFMR----SDAEAFSMDKVLRQAVVVPESK 149
           I+ E  ++R+PV  ED D I GIL  +D + ++      D     +  +LR+A  +PE++
Sbjct: 249 ILNEGINTRYPVYREDIDDIVGILHMRDAMVYVEMEEYKDRPLLEVPGLLREANFIPETR 308

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD-IDFRQLS 208
            +D + KE +S + HM IV+DE+G  +GL+T+EDILE IVG I DEYDEE+D I  R+  
Sbjct: 309 SIDTLFKEMQSGKIHMEIVVDEYGQTAGLLTMEDILEEIVGNIMDEYDEEEDFISVRE-- 366

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFGHLPARGET--IDIDGYQ 263
             ++ +  L  ++D  +     F +E+    DT+ G ++     +P  GE   +   GY 
Sbjct: 367 DGSFIMSGLTPLDDVMDVLDIEFPEEDSDTYDTLNGYLISRLDRIPQEGENPRVGFGGYT 426

Query: 264 FKVAMADSRRIIQVHV 279
           F+V  A ++ I  +HV
Sbjct: 427 FEVIKAGNKMIESIHV 442


>UniRef50_UPI0001C36BB6 hypothetical protein ChatD1_07246 n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C36BB6
          Length = 351

 Score =  132 bits (333), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 76/261 (29%), Positives = 146/261 (55%), Gaps = 11/261 (4%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E    +++++++ +  +  +++    +M+  + ++ D+   DIM  R  ++ L  + TL 
Sbjct: 64  ENVTEEDIMSMVNEGHEQGVLEAREAEMITNIFELDDKDAGDIMTHRKNLVALDGSMTLR 123

Query: 90  ECLDVII-ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF----SMDKVLRQAVV 144
           E ++ I+ E  +SR+PV  +D D I GIL  KD L    + +        +D +LR+A  
Sbjct: 124 EAVNFILKEGYNSRYPVYEKDIDDITGILHMKDALIAAENGSNGMVPICEIDGLLREAHF 183

Query: 145 VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF 204
           +PE++ +D + KE +SQ+ HM IV+DE+G  +G+VT+EDILE IVG I DEYD +++   
Sbjct: 184 IPETRNIDSLFKEMQSQKIHMVIVVDEYGQTAGIVTMEDILEEIVGSIMDEYDVDEEF-I 242

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFGHLPARGETIDID- 260
            Q    ++ +  +A +++  +     F +++    DTI G ++     +P  GE  +++ 
Sbjct: 243 AQAEDGSYIISGMAPLDEVAKTLDIEFEEDDYDSYDTINGFLISRLDRIPQEGEQTEVEY 302

Query: 261 -GYQFKVAMADSRRIIQVHVK 280
            GY FK+   +++ I  + V+
Sbjct: 303 QGYGFKILQVENKMIHTIRVQ 323


>UniRef50_O07589 UPF0053 protein yhdT n=119 Tax=Bacillales RepID=YHDT_BACSU
          Length = 461

 Score =  132 bits (333), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 86/257 (33%), Positives = 140/257 (54%), Gaps = 6/257 (2%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H    + +EL  L+ +S +N  I+      +  + +  ++  ++IMIPR +M  +    T
Sbjct: 176 HDGSHSEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAKEIMIPRKEMAAVSTEMT 235

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAK----DLLPFMRSDAEAFSMDKVLRQAV 143
           + E L+V+++  ++R+PV   DKD + G++  K    DLL     +    ++   +R  +
Sbjct: 236 MAEMLEVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLFMTEEERMKMTIHPYVRPVI 295

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
            V E+  V  +L + + +R HMAI+ DE+GG SGLVT EDILE IVGEI DE+DE++   
Sbjct: 296 EVIETIPVHDLLIKMQRERIHMAILSDEYGGTSGLVTTEDILEEIVGEIRDEFDEDEQPL 355

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
            ++L    + +     I+  N   G     E+VDTIGGL+++    + A GE+I I  Y 
Sbjct: 356 IQKLGDGHYVMDGKVRIDQVNSLLGASI-QEDVDTIGGLILKENIDIEA-GESIRIGSYT 413

Query: 264 FKVAMADSRRIIQVHVK 280
            KV   D R I Q+ +K
Sbjct: 414 IKVLKMDGRLIKQIDIK 430


>UniRef50_Q3KLS8 CorC n=10 Tax=Chlamydiaceae RepID=Q3KLS8_CHLTA
          Length = 369

 Score =  132 bits (332), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 67/207 (32%), Positives = 113/207 (54%), Gaps = 3/207 (1%)

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           R+IM P++ +  L+ +  + +   +II+  +SR P+ ++  D I G+++ KDL P    D
Sbjct: 150 REIMTPKADIFALQGDTPISQAFPLIIDEGYSRIPLFTKSIDDITGMVLVKDLSPVYYKD 209

Query: 130 AEAF-SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
                 +  +    +  PE +R   +L+EFR +R H+AIV++E+G   GLV++EDI+E I
Sbjct: 210 PHTSQPLSSIAYPPLYTPEIRRASLLLQEFRQKRCHLAIVVNEYGFTEGLVSMEDIVEEI 269

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAF 247
            GEI DEYD ++D+  +++  + W V    +I D  E FG H   E   DT+GG V    
Sbjct: 270 FGEIADEYDNQEDVHHKKIG-NAWIVDGRMNISDAEECFGLHIEHESSYDTLGGYVFHKL 328

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRI 274
           G +P +G  I  + +   +     R +
Sbjct: 329 GAVPEKGMKIYYEDFAIDILSCSDRSV 355


>UniRef50_B4U6L1 CBS domain containing protein n=1 Tax=Hydrogenobaculum sp. Y04AAS1
           RepID=B4U6L1_HYDS0
          Length = 417

 Score =  132 bits (332), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 72/251 (28%), Positives = 135/251 (53%), Gaps = 5/251 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           + ++ +++         E+   M++ V  + +  VR+IM PR  +  L+  QT+ E ++ 
Sbjct: 166 EHIVYIMQSPANAQEFSEEETQMIQKVSQMRETIVREIMTPRLDIFMLEATQTVKEVIND 225

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRM 154
           I+E  HSR P+  + KD++ G +  KDL P  +   +  +++  LR    +PE   +  +
Sbjct: 226 ILEHEHSRIPIYKDTKDNVVGYIHIKDLTPVYQHKDD--TLEIFLRPIEFIPEVMSIKNL 283

Query: 155 LKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTV 214
           L+E +     + +V+DE G +SGL+T  D+LE + G++  E+++E+  +F ++S   + V
Sbjct: 284 LQEMKKSSSQIMMVVDEHGAISGLITKHDLLEWLAGDLPQEWEDEN--EFTKMSSDVYIV 341

Query: 215 RALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
              ASIE+     G   S+  + DT+ G +M   G +P  G+  +  G++F V   D ++
Sbjct: 342 EGSASIEEVAATVGFELSENYDYDTLSGFIMANMGKIPKEGDEFEYKGFKFIVDKMDGKK 401

Query: 274 IIQVHVKIPDD 284
           I  V +KIP D
Sbjct: 402 IEHVLIKIPTD 412


>UniRef50_B9DK54 Predicted membrane protein with CBS domains n=54 Tax=Staphylococcus
           RepID=B9DK54_STACT
          Length = 469

 Score =  132 bits (331), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 76/248 (30%), Positives = 144/248 (58%), Gaps = 4/248 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+  +I +S  +  I++     ++ +    +++ +D+M+PR+QM TL    T++E L+ 
Sbjct: 184 EEIKMIINNSYNSGEINQTELAYMQNIFSFDERQAKDVMVPRTQMATLNEPFTVNELLET 243

Query: 95  IIESAHSRFPVISE-DKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDR 153
           I E   +R+P+  + DKDHI+G +  K+ L    S  +   +   + +  ++ E+ R+  
Sbjct: 244 IREYQFTRYPITEDGDKDHIKGFINVKEFLTEYAS-GKPIKISNYIHELPLISETTRISD 302

Query: 154 MLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWT 213
            L   + +R H++++IDE+GG +G++T+EDILE IVGEI DE+DE +  D  +L  +T+ 
Sbjct: 303 ALIRMQRERVHISLIIDEYGGTAGILTMEDILEEIVGEIRDEFDENEVNDVVKLGENTYQ 362

Query: 214 VRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
           +     +ED  + FG  F D +++DTIGG  +QA      + + +D    ++ ++  D+ 
Sbjct: 363 INGRVLLEDLTDEFGIEFEDSDDIDTIGGW-LQAHNTNLQQNDYVDTFYDRWIISEVDNH 421

Query: 273 RIIQVHVK 280
           +II V +K
Sbjct: 422 QIITVILK 429


>UniRef50_C5CCC5 CBS domain-containing protein n=1 Tax=Micrococcus luteus NCTC 2665
           RepID=C5CCC5_MICLC
          Length = 441

 Score =  132 bits (331), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 79/245 (32%), Positives = 138/245 (56%), Gaps = 4/245 (1%)

Query: 48  DLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVIS 107
           D++ +   ++++ V  + D  VR +M+PR+ ++T+  + TL + + + + S +SR PVI 
Sbjct: 177 DVLADSEAELIQSVFSMNDTIVRSVMVPRTDVVTIDADHTLGQAMALFLRSGNSRIPVIG 236

Query: 108 EDKDHIEGILMAKDLLPFMRSDAEAF--SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHM 165
           ED D I G+L  KD+   +  D  A    + +V+R    VPESK V  +L+E + +  H+
Sbjct: 237 EDADDIRGMLHLKDVTRALHHDGAATDTPVTEVMRDVRFVPESKSVATLLQELQRESTHV 296

Query: 166 AIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN- 224
           A+V+DE+GG +GLVT+ED++E IVGEI DE D  D  +   ++   ++V A   I DF  
Sbjct: 297 AVVVDEYGGTAGLVTLEDLIEEIVGEIYDEDDHPDRPEVEFVAPGVYSVDARMGIHDFRE 356

Query: 225 -EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
                    D++VDT+GGL+ +  G +P +G  + + G +      + RR     +++ +
Sbjct: 357 EFELPEEDEDDDVDTVGGLLAKELGRVPIQGSRVVVQGIEVVADTLEPRRNRVARLRVSE 416

Query: 284 DSPQP 288
              +P
Sbjct: 417 SPDRP 421


>UniRef50_A8GUH1 Possible hemolysin C n=15 Tax=Rickettsia RepID=HLYC_RICB8
          Length = 302

 Score =  132 bits (331), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 83/290 (28%), Positives = 161/290 (55%), Gaps = 9/290 (3%)

Query: 6   SHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIA 65
           +H + +I + +  FS + S   +  P +   ++  ++ + Q   +DE  R++L  ++ + 
Sbjct: 14  NHDNKSIFHLRKLFSPIKSLFSNKVPDDFFSVIKRLKTNSQKMTLDE--RNILANLLKLK 71

Query: 66  DQRVRDIMIPRSQMITLKRNQTLDECLDVI-IESAHSRFPVISEDKDHIEGILMAKDLLP 124
            + + DIM+PRS +  +K    ++E  + I ++  H+R  +     D+I G +  KDL  
Sbjct: 72  GKTIEDIMVPRSDIAAIKLTTNIEELNESIKVKIPHTRTLIYDGTLDNIVGFIHIKDLFK 131

Query: 125 FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDI 184
            + +  + F + K++R+ ++   S ++  +L + R ++ H+AIVIDE+GG  GLVTIED+
Sbjct: 132 ALVT-KQNFRLKKLIRKHIIAAPSMKLLDLLAKMRREKTHIAIVIDEYGGTDGLVTIEDV 190

Query: 185 LELIVGEIEDEYDEEDDID-FRQLSRHTWTVRALASIEDFNEAFGTHFS---DEEVDTIG 240
           +E +VG I+DE+D++ + D ++ ++  T    A   +E   E  G       D+E DTIG
Sbjct: 191 MEALVGRIDDEHDQKSEYDNYKVINNSTIISNARVEVEVLEEIIGEKLKDDDDDEFDTIG 250

Query: 241 GLVMQAFGHLPARGETIDI-DGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           GLV+   G++PA G  I++ +  + +V  A+ R + QV + + +   + K
Sbjct: 251 GLVLTKMGNVPAVGTKINVSENIEIEVTDANPRSLKQVKITLKNSLKRAK 300


>UniRef50_C6D831 Putative uncharacterized protein n=6 Tax=Bacillales
           RepID=C6D831_PAESJ
          Length = 445

 Score =  132 bits (331), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 75/246 (30%), Positives = 138/246 (56%), Gaps = 2/246 (0%)

Query: 40  LIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA 99
           ++ DS Q+  I+      +  +    +   ++IM+PR+ MI L  N ++ E +D+I +  
Sbjct: 190 ILNDSFQSGKINNTEYGYVSRIFAFDEMLAKEIMVPRTDMICLYTNNSMMENMDIIRKEQ 249

Query: 100 HSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFR 159
           ++RFPV +  KD+I G++  K L    + + E F+  K++   + V E   V  +LK  +
Sbjct: 250 YTRFPVATGSKDNIVGMINTKQLFLEFQENKE-FNFQKLVHPVLAVSEVLPVKTLLKRMQ 308

Query: 160 SQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALAS 219
            +R H+A+++DE+GG SG++TIEDILE IVGEI DE+D ++  +  +L+ + + +    S
Sbjct: 309 QERVHIAVLMDEYGGTSGMITIEDILEEIVGEIRDEFDTDERKEIEKLADNCYLLDGKVS 368

Query: 220 IEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           ++  +E  G     E+VDT+GG +   F   P  G+ +  +  +F +      RI +V +
Sbjct: 369 LDHVSEITGVAIDQEDVDTVGGWLFTEFTD-PKPGKEMHYENLRFIIREVGKHRIKKVEL 427

Query: 280 KIPDDS 285
            I +++
Sbjct: 428 IIEEEA 433


>UniRef50_C6LCF2 CBS domain protein n=1 Tax=Bryantella formatexigens DSM 14469
           RepID=C6LCF2_9FIRM
          Length = 289

 Score =  132 bits (331), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 77/269 (28%), Positives = 146/269 (54%), Gaps = 11/269 (4%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           G  S  L +   G  +  +E+++++ +  +  +I E    M++ + D+ D+  +D+M  R
Sbjct: 7   GLLSRKLGKNPSGSDEYEEEIISMVNEGHEQGVIQESQAQMIQNIFDLTDKEAQDVMTHR 66

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF--MRSDAEAFS 134
             +  ++    L + L  +++  HSRFPV  ++ D+I GIL  KD + +     D + + 
Sbjct: 67  RNITAIEGTMNLKDALAFMLDDTHSRFPVYLDNLDNIIGILFLKDAMRWHTRNPDYDNWQ 126

Query: 135 MDKV---LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
           +  +   LR+AV +PE++ +  + K  ++Q+  M IV DE+G  +GLV +EDILE IVG 
Sbjct: 127 IKDIPSLLRKAVFIPETRDLSPLFKSMQTQKLQMVIVSDEYGQTAGLVAMEDILEEIVGN 186

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I+DEYD ++ +   + +   + +   A +++ +EA      D E +T+ G ++   G +P
Sbjct: 187 IQDEYDNDEPV--IEKAGDDFLISGFAPLDEVSEALQLSLDDVEFETLNGFLISKLGRIP 244

Query: 252 A---RGETIDIDGYQFKVAMADSRRIIQV 277
           +   R E I  DGY F++    ++ I +V
Sbjct: 245 SDDDRSEII-TDGYSFRILSVANKTIERV 272


>UniRef50_C9LMB7 Putative transporter n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LMB7_9FIRM
          Length = 436

 Score =  131 bits (330), Expect = 2e-29,   Method: Compositional matrix adjust.
 Identities = 78/246 (31%), Positives = 139/246 (56%), Gaps = 8/246 (3%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           DE+  ++ +S +   ++     +++   D  D  VRD+MIPR+ M+ L  N  +D     
Sbjct: 180 DEIRCIVEESHRGGRLNTLENTLIKNSFDFFDLDVRDVMIPRNDMVVLDFNDDMDVMRRN 239

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPESKRVDR 153
           I ++ H+ +PV  EDKDHI G +  KD L   +R +   +++ +++R+ + VPE      
Sbjct: 240 ISKTHHTCYPVCMEDKDHILGFIHVKDFLESLLRGE---YNIKRIMREILTVPEVMPAPA 296

Query: 154 MLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI-EDEYDEEDDIDFRQLSRHTW 212
           +L+  +++R ++A+V+DE+GG SGLVT+ED++E + GEI ++E +   +I   +++ H +
Sbjct: 297 LLQMMKNKRTYLAVVVDEYGGTSGLVTLEDLMEELAGEIPQNESNAPAEI--LRVNDHVY 354

Query: 213 TVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
                  +ED +E     F DEE  +TIGGL+      +P  G+ I   G++F V     
Sbjct: 355 EFDGTVILEDVSERLQMEFDDEERNNTIGGLIFSKLERIPQVGDHISFGGWKFTVLKMYG 414

Query: 272 RRIIQV 277
            RI++V
Sbjct: 415 FRIMRV 420


>UniRef50_A0L637 Putative uncharacterized protein n=5 Tax=cellular organisms
           RepID=A0L637_MAGSM
          Length = 523

 Score =  131 bits (330), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 74/237 (31%), Positives = 128/237 (54%), Gaps = 8/237 (3%)

Query: 44  SGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRF 103
           +G  DL DE   + +  +++  +Q V ++M PRS M+TL  + T++E L+V+     SR 
Sbjct: 182 AGDGDL-DEVEAEYIHNIIEFGNQTVEEVMTPRSNMVTLNMDDTMEEVLNVLRTERVSRV 240

Query: 104 PVISEDKDHIEGILMAKDLLPFMRSDAEAFS----MDKVLRQAVVVPESKRVDRMLKEFR 159
           PV  E+ + + G+L  +DLL    +D + F     +  +LR+   VPE+K +  ++  FR
Sbjct: 241 PVFDEENEEVVGVLYYRDLL---SNDLDQFKNMEELRSILRRPYYVPETKPILDLMHNFR 297

Query: 160 SQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALAS 219
            ++  +A+++DE+GG  G+VT+ D+LE I G+I D  D ++D     L    + +     
Sbjct: 298 EKKRSLALILDEYGGTIGMVTMGDLLESIFGDIHDPEDPDNDATVESLENGCYRLDGNLD 357

Query: 220 IEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ 276
           +E  N      F  +  DTI GL+M A G LP  G  I +  + F++   +  RI++
Sbjct: 358 VEQANLLMQADFDTQISDTIAGLLMHAHGELPEEGSVIPLGEWCFRITRMEGTRIME 414


>UniRef50_C5SJL8 CBS domain containing protein n=1 Tax=Asticcacaulis excentricus CB
           48 RepID=C5SJL8_9CAUL
          Length = 296

 Score =  131 bits (329), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 90/253 (35%), Positives = 135/253 (53%), Gaps = 17/253 (6%)

Query: 52  EDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKD 111
           E T D++E      + RV D+M PR  +I ++   TL E + V +ES HSR PV S++ D
Sbjct: 42  EATNDLIEHARAFQNLRVSDVMTPRVDIIGIEDTATLSELVRVCVESEHSRLPVYSDNLD 101

Query: 112 HIEGILMAKDLLPFMRS-------DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYH 164
           H  G++  KD+   +         D +A   D++ R+ + VP +     +L + +++R H
Sbjct: 102 HPVGVIHVKDVFKLLAPSDDRRIPDWDALVTDRLKRELIYVPGAMSATDLLLKMQTERSH 161

Query: 165 MAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN 224
           MA+VIDE GG  GLVT+ED+LE +VG+I DEYD+++  +  + +     V     +E   
Sbjct: 162 MALVIDEHGGTDGLVTLEDLLEAVVGDIADEYDDDEVDELVETAEGQIEVSGRVELETLE 221

Query: 225 EAFGTHF----SDEEVDTIGGLVMQAFGHLPARGETIDI--DGYQFKVAMADSRRI---- 274
           E  G       S+EEVDT+GGLV    G +P  GE I     G   +V  AD RRI    
Sbjct: 222 ERLGLRLFPENSEEEVDTLGGLVAVLAGRVPQPGEIIPYAAAGIDIEVLDADQRRIKRLR 281

Query: 275 IQVHVKIPDDSPQ 287
           +  H + PD  P+
Sbjct: 282 LHRHERKPDLIPE 294


>UniRef50_C9LYN4 CBS domain protein n=2 Tax=Selenomonas RepID=C9LYN4_9FIRM
          Length = 481

 Score =  131 bits (329), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 80/249 (32%), Positives = 140/249 (56%), Gaps = 2/249 (0%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
             +E+  L+ +S +   ID+   + ++ V D AD  VR+IMIPR+ M+ L    +L+E +
Sbjct: 196 TEEEIRVLMEESHRQGFIDKTELEFVDNVFDFADLSVREIMIPRTDMVCLDLEDSLEESI 255

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
           ++ +E   +R+P+    KD+I G L  KD L  +    E   + K+ R A+VVPE+  V 
Sbjct: 256 EMAMEERLTRYPICDGGKDNIIGFLHIKDFLQTLYKKEEP-DLRKLARHALVVPEAMAVS 314

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
           R+L+  + +R  +AIV+DE+GG +G+VTIED++E IVG+I+DE+D +  +   +     +
Sbjct: 315 RLLQTMQQERSQLAIVVDEYGGTAGMVTIEDVIEEIVGDIQDEFDTDRPL-VEKKGACLY 373

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
           +V A   +E+  +       +EE+D++GG +     + P  G+       QF V   +  
Sbjct: 374 SVDAKMLLEELEDILEVAIDEEEIDSVGGWLSAHVDNPPRIGQKAAFGDAQFFVEETEGV 433

Query: 273 RIIQVHVKI 281
           RI +V  ++
Sbjct: 434 RITRVLCRL 442


>UniRef50_UPI0000510515 magnesium and cobalt efflux protein n=1 Tax=Brevibacterium linens
           BL2 RepID=UPI0000510515
          Length = 442

 Score =  131 bits (329), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 75/244 (30%), Positives = 134/244 (54%), Gaps = 2/244 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
           ++ +EL +L+R S +  ++DE T D+LE  +  +++   D+M PR++M ++ ++ T    
Sbjct: 179 RSPEELTSLVRHSAEEGMLDEQTADLLERTLSFSERTAEDVMTPRTRMSSVVKDTTARAI 238

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           ++   E+  SRFPV  EDKDHI G++  K       ++ +      ++ +   +PE+  +
Sbjct: 239 IEQARETGFSRFPVAGEDKDHIVGVVHVKQAFAVPLANRDDAYAGGLMTEVTEIPETLLL 298

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D +L E R+Q   MA+V+DEFGG +G+VT+ED++E +VGE+ DE+D    +  R     T
Sbjct: 299 DPLLMELRAQGLQMAVVVDEFGGTAGVVTLEDVVEELVGEVADEHDRM-RVAARPARDGT 357

Query: 212 WTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
           W V      ++ +   G     D + +T+ G V++  G +P  G+ +  D    +V    
Sbjct: 358 WIVPGQLRPDEVSSTVGLQIPEDSDYETLAGFVLKELGRIPEPGDQVRTDDALIRVERMH 417

Query: 271 SRRI 274
            RRI
Sbjct: 418 GRRI 421


>UniRef50_A6CIW3 Probable hemolysin n=2 Tax=Bacillus RepID=A6CIW3_9BACI
          Length = 445

 Score =  131 bits (329), Expect = 3e-29,   Method: Compositional matrix adjust.
 Identities = 73/232 (31%), Positives = 129/232 (55%), Gaps = 5/232 (2%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           M+  + +  D+   DI+  R+ M  L  +  L+E L+++ +  ++RFPV  + +D+I G+
Sbjct: 204 MINNIFEFNDKIASDIITHRTDMCVLSIDADLEEVLEMVSKEGYTRFPVYEKVRDNIVGV 263

Query: 117 LMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           L +KDL  ++  D E F +  V+R+   V ES+ +D +    ++   H+AIV+DEFGG  
Sbjct: 264 LHSKDLFQYIGKD-EDFDLRNVIRKPYFVLESQTIDVLFTTMQTNNVHIAIVLDEFGGTE 322

Query: 177 GLVTIEDILELIVGEIED--EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE 234
           G++TIED++E IVGEI      +   + + +Q+S + + V+ +A + +       HFS E
Sbjct: 323 GMITIEDVIEEIVGEIYSESIEEGIYEEEIKQISPNQYEVKGIARLWELEAVLKVHFSTE 382

Query: 235 EVDTIGGLVMQAFGHLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           E+DT+ G ++   G+ P+  E   ID    QF+V      R+ +  V +  D
Sbjct: 383 ELDTLSGFLIHELGYFPSVQERPVIDYKHLQFEVLEIKDNRVEKAMVTVKTD 434


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q5SKB4 Hemolysin-related protein n=3 Tax=Thermus RepID=...   339   5e-92
UniRef50_D2DIN9 CBS domain-containing protein n=1 Tax=uncultured...   326   6e-88
UniRef50_B8G6A7 Putative uncharacterized protein n=3 Tax=Chlorof...   324   2e-87
UniRef50_D0MD79 CBS domain containing protein n=1 Tax=Rhodotherm...   324   3e-87
UniRef50_B8CXI7 Putative membrane CBS domain protein n=1 Tax=Hal...   323   7e-87
UniRef50_B2I8U5 CBS domain containing protein n=17 Tax=Xanthomon...   321   2e-86
UniRef50_B8I559 Putative uncharacterized protein n=1 Tax=Clostri...   321   2e-86
UniRef50_Q1AX40 Putative uncharacterized protein n=1 Tax=Rubroba...   319   6e-86
UniRef50_Q3A2F6 Uncharacterized CBS domain-containing protein n=...   319   7e-86
UniRef50_A9WFQ5 CBS domain containing protein n=4 Tax=Chloroflex...   319   7e-86
UniRef50_D1CDD2 CBS domain containing protein n=1 Tax=Thermobacu...   318   1e-85
UniRef50_Q9KTE3 Magnesium and cobalt efflux protein corC n=42 Ta...   318   1e-85
UniRef50_B7IDY0 Integral membrane protein with CBS domains n=4 T...   318   1e-85
UniRef50_C1SMP1 CBS domain-containing protein n=1 Tax=Denitrovib...   317   3e-85
UniRef50_B0PAE4 Putative uncharacterized protein n=2 Tax=Clostri...   316   5e-85
UniRef50_A4VQY6 Metal ion transporter, putative n=2 Tax=Gammapro...   315   1e-84
UniRef50_C7IJK2 CBS domain containing protein n=5 Tax=Firmicutes...   314   2e-84
UniRef50_A7NHB2 CBS domain containing protein n=1 Tax=Roseiflexu...   314   3e-84
UniRef50_D1N3F2 Putative uncharacterized protein n=1 Tax=Victiva...   313   4e-84
UniRef50_A5UY55 Putative uncharacterized protein n=3 Tax=Chlorof...   313   6e-84
UniRef50_Q48DN5 Metal ion transporter, putative n=16 Tax=Proteob...   313   7e-84
UniRef50_D0KZZ4 CBS domain containing protein n=1 Tax=Halothioba...   312   1e-83
UniRef50_Q3JVV5 Magnesium and cobalt efflux protein CorC n=105 T...   312   1e-83
UniRef50_A7HLR9 Putative uncharacterized protein n=1 Tax=Fervido...   311   2e-83
UniRef50_Q1IYV3 CBS domain-containing protein DUF21 n=4 Tax=Bact...   311   2e-83
UniRef50_C7GAD7 CBS domain protein n=9 Tax=Bacteria RepID=C7GAD7...   311   2e-83
UniRef50_Q9CM13 Magnesium and cobalt efflux protein corC n=264 T...   310   3e-83
UniRef50_B7J5B5 Magnesium and cobalt efflux protein, putative n=...   310   3e-83
UniRef50_Q7VRA4 Haemolysin-related protein n=2 Tax=Candidatus Bl...   309   6e-83
UniRef50_D1B5K7 Putative uncharacterized protein n=1 Tax=Therman...   309   9e-83
UniRef50_D1Y8K6 CBS/transporter domain protein n=1 Tax=Pyramidob...   308   1e-82
UniRef50_Q74EV6 CBS domain protein n=9 Tax=Desulfuromonadales Re...   308   1e-82
UniRef50_A1WVF4 CBS domain containing protein n=2 Tax=Ectothiorh...   308   2e-82
UniRef50_Q5ZVK1 Mg2+ and Co2+ transporter CorC n=6 Tax=Legionell...   307   3e-82
UniRef50_Q47RN3 CBS domain protein n=1 Tax=Thermobifida fusca YX...   306   4e-82
UniRef50_D2LWG5 Putative uncharacterized protein n=3 Tax=Bacillu...   306   4e-82
UniRef50_C1TQS8 CBS domain-containing protein n=2 Tax=Synergista...   306   7e-82
UniRef50_Q2JP27 Putative transporter, HlyC/CorC (HCC) family n=2...   305   1e-81
UniRef50_C5VQE4 CBS domain integral membrane protein n=9 Tax=Clo...   305   1e-81
UniRef50_B9KAC3 Hemolysin-related protein n=1 Tax=Thermotoga nea...   305   1e-81
UniRef50_B8G2E5 Putative uncharacterized protein n=3 Tax=Clostri...   305   2e-81
UniRef50_C7LZP2 CBS domain containing protein n=1 Tax=Acidimicro...   304   2e-81
UniRef50_C6L9Q9 CBS domain protein n=6 Tax=Clostridiales RepID=C...   304   2e-81
UniRef50_B5JWG7 CBS domain containing protein n=3 Tax=Gammaprote...   304   3e-81
UniRef50_A9KQ60 Putative uncharacterized protein n=8 Tax=Clostri...   303   7e-81
UniRef50_C3WJU6 Magnesium and cobalt efflux protein corC n=15 Ta...   302   1e-80
UniRef50_C1ZDU6 CBS domain-containing protein n=1 Tax=Planctomyc...   301   2e-80
UniRef50_Q3SVM7 Mg2+ and Co2+ transporter CorB family n=15 Tax=A...   301   2e-80
UniRef50_C6J8N4 Putative uncharacterized protein n=1 Tax=Ruminoc...   301   2e-80
UniRef50_A9BGT5 Putative uncharacterized protein n=1 Tax=Petroto...   300   4e-80
UniRef50_B8KMV1 Magnesium and cobalt efflux protein CorC n=3 Tax...   299   9e-80
UniRef50_B7RC07 CBS domain integral membrane protein n=5 Tax=The...   299   1e-79
UniRef50_A1AQM4 CBS domain containing protein n=9 Tax=Desulfurom...   299   1e-79
UniRef50_B5YFP5 CBS domain protein n=1 Tax=Thermodesulfovibrio y...   298   1e-79
UniRef50_B8J2R3 CBS domain containing protein n=3 Tax=Desulfovib...   298   1e-79
UniRef50_Q72A49 CBS/transporter associated domain protein n=4 Ta...   298   1e-79
UniRef50_UPI0001C36BB6 hypothetical protein ChatD1_07246 n=1 Tax...   298   2e-79
UniRef50_Q1DCR5 CBS/transporter associated domain protein n=2 Ta...   298   2e-79
UniRef50_A6CBK3 Hemolysin protein n=1 Tax=Planctomyces maris DSM...   298   2e-79
UniRef50_A9B0K1 Putative uncharacterized protein n=1 Tax=Herpeto...   298   2e-79
UniRef50_D1C4W4 Putative uncharacterized protein n=1 Tax=Sphaero...   298   2e-79
UniRef50_D2RIW5 CBS domain containing protein n=2 Tax=Acidaminoc...   297   3e-79
UniRef50_C9L5N7 Hemolysin-related protein n=1 Tax=Blautia hansen...   297   3e-79
UniRef50_D1AFV9 Putative uncharacterized protein n=1 Tax=Sebalde...   297   3e-79
UniRef50_B2V0V1 CBS/transporter domain protein n=18 Tax=Clostrid...   296   6e-79
UniRef50_Q2FTJ8 Putative uncharacterized protein n=4 Tax=Methano...   296   6e-79
UniRef50_Q1YQV9 Magnesium and cobalt efflux protein CorC n=1 Tax...   296   6e-79
UniRef50_D2LDC4 Putative uncharacterized protein n=1 Tax=Rhodomi...   296   6e-79
UniRef50_P74409 UPF0053 protein sll0260 n=28 Tax=cellular organi...   296   7e-79
UniRef50_A3ZXV1 Hemolysin protein n=1 Tax=Blastopirellula marina...   296   7e-79
UniRef50_C5PXG9 TlyC family hemolysin n=5 Tax=Sphingobacteriales...   296   8e-79
UniRef50_C4Z1L1 Putative hemolysin n=2 Tax=Bacteria RepID=C4Z1L1...   295   1e-78
UniRef50_C3L2Y2 Transporter, HlyC/CorC family n=26 Tax=Bacteria ...   295   1e-78
UniRef50_B2V0W8 Putative membrane CBS domain protein n=14 Tax=Cl...   295   1e-78
UniRef50_B7GEW2 Hemolysin related protein containing CBS domains...   295   1e-78
UniRef50_Q1K126 CBS domain protein n=2 Tax=Desulfuromonadales Re...   295   1e-78
UniRef50_D1Y8K5 Putative transporter n=1 Tax=Pyramidobacter pisc...   294   2e-78
UniRef50_B8JAD7 Putative uncharacterized protein n=4 Tax=Anaerom...   294   2e-78
UniRef50_P67130 UPF0053 protein Rv2366c/MT2435 n=36 Tax=Actinomy...   294   3e-78
UniRef50_C7RRT5 CBS domain containing protein n=1 Tax=Candidatus...   294   3e-78
UniRef50_A0PYY8 Integral membrane protein with CBS domains n=15 ...   293   4e-78
UniRef50_B9ZL46 CBS domain containing protein n=2 Tax=Gammaprote...   293   4e-78
UniRef50_B5YET1 GldE n=2 Tax=Dictyoglomus RepID=B5YET1_DICT6          292   7e-78
UniRef50_B9Z7Q6 Putative uncharacterized protein n=1 Tax=Lutiell...   292   1e-77
UniRef50_D1C1Y5 CBS domain containing protein n=1 Tax=Sphaerobac...   292   1e-77
UniRef50_B6IU27 CBS domain protein n=2 Tax=Rhodospirillum RepID=...   292   1e-77
UniRef50_B9L251 Magnesium and cobalt efflux protein corC n=1 Tax...   292   1e-77
UniRef50_A5EY48 Transporter associated domain protein n=2 Tax=Ca...   291   2e-77
UniRef50_C8VVX2 Putative uncharacterized protein n=2 Tax=Clostri...   291   2e-77
UniRef50_C5EUB4 Membrane-anchored CBS domain-containing protein-...   291   2e-77
UniRef50_Q2NIR0 Hymolysin-related protein n=5 Tax=Candidatus Phy...   291   2e-77
UniRef50_C6W3X5 Putative uncharacterized protein n=1 Tax=Dyadoba...   290   3e-77
UniRef50_C6IW85 Putative uncharacterized protein n=1 Tax=Paeniba...   290   4e-77
UniRef50_Q310P2 CBS n=6 Tax=Desulfovibrionaceae RepID=Q310P2_DESDG    290   4e-77
UniRef50_B8J8L5 CBS domain containing protein n=4 Tax=Anaeromyxo...   290   5e-77
UniRef50_C8X404 CBS domain containing protein n=2 Tax=Desulfovib...   290   5e-77
UniRef50_C9KJP9 CBS domain protein n=3 Tax=Veillonellaceae RepID...   289   5e-77
UniRef50_A8PND0 Magnesium and cobalt efflux protein CorC n=1 Tax...   289   6e-77
UniRef50_C8WNW4 Putative uncharacterized protein n=1 Tax=Eggerth...   289   6e-77
UniRef50_C7DFD3 CBS domain protein n=6 Tax=Rhodobacteraceae RepI...   289   6e-77
UniRef50_C6NUU3 Magnesium and cobalt efflux protein CorC n=1 Tax...   289   6e-77
UniRef50_A8KYW4 CBS domain containing protein n=33 Tax=Actinomyc...   289   1e-76
UniRef50_D1AH17 Putative uncharacterized protein n=1 Tax=Sebalde...   289   1e-76
UniRef50_C3X3R1 Magnesium and cobalt efflux protein n=1 Tax=Oxal...   288   1e-76
UniRef50_B3QS78 Putative uncharacterized protein n=3 Tax=Bacteri...   288   1e-76
UniRef50_A9KLG3 Putative uncharacterized protein n=1 Tax=Clostri...   288   1e-76
UniRef50_B0MHL2 Putative uncharacterized protein n=2 Tax=Bacteri...   288   2e-76
UniRef50_C9LMB7 Putative transporter n=1 Tax=Dialister invisus D...   288   2e-76
UniRef50_B5Y9X2 CBS domain protein n=1 Tax=Coprothermobacter pro...   288   2e-76
UniRef50_A8DJD8 CBS domain protein n=1 Tax=Candidatus Chloracido...   287   2e-76
UniRef50_UPI0001BCCCA8 CBS domain-containing protein n=1 Tax=Aer...   287   2e-76
UniRef50_A3EP54 Putative uncharacterized protein n=2 Tax=Leptosp...   287   3e-76
UniRef50_B6JNY8 Hemolysin domain-containing protein n=23 Tax=Cam...   287   3e-76
UniRef50_D1VUR6 CBS/transporter domain protein n=1 Tax=Peptoniph...   287   3e-76
UniRef50_C8XF87 CBS domain containing protein n=11 Tax=Bacteria ...   287   4e-76
UniRef50_C6QET7 Putative uncharacterized protein n=1 Tax=Hyphomi...   286   4e-76
UniRef50_B8GI66 Putative uncharacterized protein n=1 Tax=Methano...   286   5e-76
UniRef50_A9VF50 Putative uncharacterized protein n=6 Tax=Bacillu...   286   6e-76
UniRef50_A2SJR8 CBS domain protein n=8 Tax=Burkholderiales RepID...   286   6e-76
UniRef50_C2ECT1 Hemolysin n=1 Tax=Lactobacillus ruminis ATCC 256...   286   7e-76
UniRef50_Q2FN37 Putative uncharacterized protein n=1 Tax=Methano...   286   7e-76
UniRef50_C7NDD7 CBS domain containing protein n=3 Tax=Leptotrich...   286   8e-76
UniRef50_C9KMQ2 CBS domain protein n=1 Tax=Mitsuokella multacida...   286   9e-76
UniRef50_C4V614 TlyC family hemolysin n=14 Tax=cellular organism...   286   9e-76
UniRef50_A0LG68 CBS domain containing protein n=1 Tax=Syntrophob...   286   9e-76
UniRef50_C2MBP5 Gliding motility-associated protein GldE n=1 Tax...   285   1e-75
UniRef50_C0CHP0 Putative uncharacterized protein n=1 Tax=Blautia...   285   1e-75
UniRef50_A9F240 Conserved hypothetical membrane protein n=1 Tax=...   285   1e-75
UniRef50_Q7NMI1 Glr0785 protein n=2 Tax=Bacteria RepID=Q7NMI1_GLOVI   285   1e-75
UniRef50_Q3ZYX1 Probable hemolysin-related protein n=5 Tax=Dehal...   285   1e-75
UniRef50_A2SSZ1 Putative uncharacterized protein n=1 Tax=Methano...   285   1e-75
UniRef50_Q30WW6 CBS n=5 Tax=Proteobacteria RepID=Q30WW6_DESDG         285   1e-75
UniRef50_Q1IKR7 Putative uncharacterized protein n=1 Tax=Candida...   285   2e-75
UniRef50_Q67QV0 Putative hemolysin n=1 Tax=Symbiobacterium therm...   284   3e-75
UniRef50_A9I003 Magnesium and cobalt efflux protein n=5 Tax=Bord...   283   4e-75
UniRef50_C2HJY2 HCC HlyC/CorC family transporter n=2 Tax=Finegol...   283   4e-75
UniRef50_C7HS55 Transporter n=3 Tax=Anaerococcus RepID=C7HS55_9FIRM   283   6e-75
UniRef50_Q164J1 CBS domain protein n=37 Tax=Rhodobacterales RepI...   282   6e-75
UniRef50_C4GJN3 Putative uncharacterized protein n=1 Tax=Kingell...   282   7e-75
UniRef50_D1BMR3 Transporter-associated region n=3 Tax=Veillonell...   282   7e-75
UniRef50_C7LQH5 Putative uncharacterized protein n=1 Tax=Desulfo...   282   8e-75
UniRef50_C1XJH4 CBS domain-containing protein n=1 Tax=Meiothermu...   282   8e-75
UniRef50_D1Y9A3 CBS domain protein n=3 Tax=Propionibacterium acn...   282   8e-75
UniRef50_Q6MCC0 Putative uncharacterized protein n=2 Tax=Parachl...   282   9e-75
UniRef50_D0MK91 CBS domain containing protein n=1 Tax=Rhodotherm...   282   1e-74
UniRef50_Q6MC55 Putative uncharacterized protein n=1 Tax=Candida...   282   1e-74
UniRef50_C3MCE9 Putative uncharacterized protein n=1 Tax=Rhizobi...   282   1e-74
UniRef50_A8SE58 Putative uncharacterized protein n=2 Tax=Bacteri...   282   1e-74
UniRef50_C9RLZ8 CBS domain containing protein n=1 Tax=Fibrobacte...   282   1e-74
UniRef50_B6FN86 Putative uncharacterized protein n=2 Tax=Clostri...   282   1e-74
UniRef50_A4EBJ7 Putative uncharacterized protein n=1 Tax=Collins...   281   2e-74
UniRef50_D1CH59 Putative uncharacterized protein n=1 Tax=Thermob...   281   2e-74
UniRef50_C1A9X1 Hypothetical membrane protein n=1 Tax=Gemmatimon...   281   2e-74
UniRef50_Q1IKR3 CBS domain protein n=1 Tax=Candidatus Koribacter...   281   2e-74
UniRef50_D1VTC9 Integral membrane protein n=1 Tax=Peptoniphilus ...   281   2e-74
UniRef50_C8P0P9 CBS domain protein n=1 Tax=Erysipelothrix rhusio...   281   2e-74
UniRef50_A5ZVW9 Putative uncharacterized protein n=1 Tax=Ruminoc...   281   3e-74
UniRef50_A4FLP3 Magnesium and cobalt efflux protein CorC n=3 Tax...   281   3e-74
UniRef50_A1QYK9 Magnesium and cobalt efflux protein CorC n=21 Ta...   281   3e-74
UniRef50_Q0G3C6 Putative uncharacterized protein n=2 Tax=Auranti...   281   3e-74
UniRef50_C0FYH2 Putative uncharacterized protein n=1 Tax=Rosebur...   280   3e-74
UniRef50_A0JX40 CBS domain containing protein n=4 Tax=Micrococca...   280   4e-74
UniRef50_A8ZTS5 Putative uncharacterized protein n=2 Tax=Desulfo...   280   5e-74
UniRef50_C0EHV3 Putative uncharacterized protein n=1 Tax=Clostri...   280   5e-74
UniRef50_C2BH63 HCC HlyC/CorC family transporter n=2 Tax=Anaeroc...   279   5e-74
UniRef50_UPI0001BC3544 hypothetical protein BcroD2_01764 n=1 Tax...   279   5e-74
UniRef50_A4J4V5 Putative uncharacterized protein n=1 Tax=Desulfo...   279   8e-74
UniRef50_C0W312 HCC HlyC/CorC family transporter n=1 Tax=Actinom...   279   9e-74
UniRef50_B9Y7L5 Putative uncharacterized protein n=1 Tax=Holdema...   279   1e-73
UniRef50_Q6N606 Probable HlyC/CorC family of transporters with 2...   279   1e-73
UniRef50_C6J7K3 Putative uncharacterized protein n=2 Tax=Bacilla...   278   1e-73
UniRef50_Q01WS1 Putative uncharacterized protein n=1 Tax=Candida...   278   1e-73
UniRef50_A9M203 Magnesium and cobalt transporter n=27 Tax=Neisse...   278   1e-73
UniRef50_Q87DZ3 Hemolysin n=20 Tax=Xanthomonadaceae RepID=Q87DZ3...   278   1e-73
UniRef50_B3QY17 CBS domain containing protein n=1 Tax=Chloroherp...   278   1e-73
UniRef50_Q8YM44 All5096 protein n=16 Tax=Cyanobacteria RepID=Q8Y...   278   1e-73
UniRef50_C6LCF2 CBS domain protein n=1 Tax=Bryantella formatexig...   278   1e-73
UniRef50_A6LDG3 Hemolysin-related protein n=23 Tax=Bacteroidales...   278   1e-73
UniRef50_Q1K2A8 Putative uncharacterized protein n=1 Tax=Desulfu...   277   2e-73
UniRef50_A6U9C9 Putative uncharacterized protein n=2 Tax=Sinorhi...   277   2e-73
UniRef50_B1I646 Putative uncharacterized protein n=1 Tax=Candida...   277   2e-73
UniRef50_UPI0001C360F2 putative hemolysin-related protein n=2 Ta...   277   2e-73
UniRef50_Q01P08 CBS domain containing protein n=1 Tax=Candidatus...   277   3e-73
UniRef50_B3WFB2 Transport protein n=8 Tax=Lactobacillus RepID=B3...   277   3e-73
UniRef50_UPI000050F785 CBS domain-containing protein n=1 Tax=Bre...   277   3e-73
UniRef50_A0LRV3 Putative uncharacterized protein n=1 Tax=Acidoth...   277   3e-73
UniRef50_C0QRS4 CBS/transporter-associated domain protein n=5 Ta...   277   3e-73
UniRef50_C4GBW1 Putative uncharacterized protein n=1 Tax=Shuttle...   277   3e-73
UniRef50_A5CRB2 Conserved membrane protein n=4 Tax=Actinobacteri...   277   3e-73
UniRef50_A9NGP1 Putative hemolysin-related protein n=2 Tax=Bacte...   277   4e-73
UniRef50_C4L4N6 Putative uncharacterized protein n=2 Tax=Bacilla...   277   4e-73
UniRef50_Q609I4 CBS domain protein n=2 Tax=Proteobacteria RepID=...   277   4e-73
UniRef50_UPI000196CD6F hypothetical protein CATMIT_02806 n=1 Tax...   277   4e-73
UniRef50_A6CIW3 Probable hemolysin n=2 Tax=Bacillus RepID=A6CIW3...   277   4e-73
UniRef50_C6HVJ5 Putative uncharacterized protein n=1 Tax=Leptosp...   277   4e-73
UniRef50_A7VCA4 Putative uncharacterized protein n=2 Tax=Clostri...   276   5e-73
UniRef50_C7PAX6 Putative uncharacterized protein n=1 Tax=Chitino...   276   6e-73
UniRef50_C4ZBH2 Hemolysin n=1 Tax=Eubacterium rectale ATCC 33656...   276   6e-73
UniRef50_C9MVS3 CBS domain protein n=3 Tax=Fusobacteriaceae RepI...   276   8e-73
UniRef50_C2BV08 HCC HlyC/CorC family transporter n=3 Tax=Mobilun...   276   8e-73
UniRef50_A9BXY0 CBS domain containing protein n=17 Tax=cellular ...   275   1e-72
UniRef50_A7VIV6 Putative uncharacterized protein n=2 Tax=Clostri...   275   1e-72
UniRef50_A7VVN2 Putative uncharacterized protein n=1 Tax=Clostri...   275   1e-72
UniRef50_D2RTA7 Putative uncharacterized protein n=3 Tax=Haloter...   275   2e-72
UniRef50_C4G6D4 Putative uncharacterized protein n=1 Tax=Abiotro...   274   2e-72
UniRef50_Q0VN63 Metal ion transporter n=15 Tax=Gammaproteobacter...   274   2e-72
UniRef50_B1XKG2 CBS domain protein n=2 Tax=Chroococcales RepID=B...   274   2e-72
UniRef50_C7RN87 Putative uncharacterized protein n=1 Tax=Candida...   274   2e-72
UniRef50_A7HZ85 CBS domain containing protein n=1 Tax=Parvibacul...   274   2e-72
UniRef50_O07589 UPF0053 protein yhdT n=119 Tax=Bacillales RepID=...   274   2e-72
UniRef50_UPI0001B44AE5 CBS domain protein n=1 Tax=Listeria monoc...   274   2e-72
UniRef50_Q0C626 CBS/transporter domain protein n=7 Tax=Alphaprot...   274   3e-72
UniRef50_D2NSB8 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NS...   274   3e-72
UniRef50_B8GZ20 Magnesium and cobalt efflux protein corC-like pr...   274   3e-72
UniRef50_A9U7Q9 Predicted protein (Fragment) n=1 Tax=Physcomitre...   274   3e-72
UniRef50_A9NG07 Membrane-anchored CBS-domain containing protein ...   274   3e-72
UniRef50_D2NT77 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NT...   274   3e-72
UniRef50_C1F1N4 CBS/transporter domain protein n=1 Tax=Acidobact...   274   4e-72
UniRef50_UPI0001973384 hypothetical protein ClM62_01605 n=1 Tax=...   273   5e-72
UniRef50_C1F7E2 CBS/transporter domain protein n=1 Tax=Acidobact...   273   5e-72
UniRef50_B6BWN1 Putative uncharacterized protein n=1 Tax=beta pr...   273   6e-72
UniRef50_B6FYX0 Putative uncharacterized protein n=1 Tax=Clostri...   272   7e-72
UniRef50_C0W0A3 HCC HlyC/CorC family transporter n=1 Tax=Actinom...   272   7e-72
UniRef50_C1DDZ1 Mg/Co transporter-like protein n=7 Tax=Pseudomon...   272   1e-71
UniRef50_D0RQJ3 CBS domain containing protein n=1 Tax=alpha prot...   272   1e-71
UniRef50_B2S3N8 Hemolysin n=5 Tax=Spirochaetaceae RepID=B2S3N8_T...   272   1e-71
UniRef50_C0GM71 CBS domain containing protein n=1 Tax=Desulfonat...   271   1e-71
UniRef50_C9LYN4 CBS domain protein n=2 Tax=Selenomonas RepID=C9L...   271   2e-71
UniRef50_B3QAC3 CBS domain containing protein n=15 Tax=Rhizobial...   271   2e-71
UniRef50_Q2W097 Putative Mg2+ and Co2+ transporter CorB n=1 Tax=...   271   2e-71
UniRef50_UPI0000510515 magnesium and cobalt efflux protein n=1 T...   271   2e-71
UniRef50_B7K5Y6 Putative uncharacterized protein n=6 Tax=Cyanoba...   271   2e-71
UniRef50_B4U6L1 CBS domain containing protein n=1 Tax=Hydrogenob...   271   3e-71
UniRef50_C4GB29 Putative uncharacterized protein n=1 Tax=Shuttle...   271   3e-71
UniRef50_C6D831 Putative uncharacterized protein n=6 Tax=Bacilla...   271   3e-71
UniRef50_C0QYZ5 Hemolysin protein n=2 Tax=Brachyspira RepID=C0QY...   270   3e-71
UniRef50_UPI00016C05A3 CBS/transporter-associated domain protein...   270   4e-71
UniRef50_C1D3R1 Putative hemolysin; putative membrane protein n=...   270   4e-71
UniRef50_Q18E42 CBS domain protein n=11 Tax=Halobacteriaceae Rep...   270   5e-71
UniRef50_C6BSI1 CBS domain containing protein n=2 Tax=Desulfovib...   270   5e-71
UniRef50_D0LKP6 Putative uncharacterized protein n=1 Tax=Haliang...   270   5e-71
UniRef50_C0K042 Hemolysin-related protein n=1 Tax=uncultured bac...   269   6e-71
UniRef50_C3RN25 Putative uncharacterized protein n=1 Tax=Mollicu...   269   6e-71
UniRef50_Q6ZUX1 cDNA FLJ43252 fis, clone HEART2006909 n=23 Tax=c...   269   6e-71
UniRef50_B8FGS6 Putative uncharacterized protein n=1 Tax=Desulfa...   269   7e-71
UniRef50_D0M5E7 Hemolysin n=15 Tax=Vibrionales RepID=D0M5E7_VIBSE     269   7e-71
UniRef50_C7MLQ1 CBS domain-containing protein n=8 Tax=Coriobacte...   269   7e-71
UniRef50_C3J7T2 CBS domain pair n=4 Tax=Bacteria RepID=C3J7T2_9PORP   269   8e-71
UniRef50_UPI0001C3727C hypothetical protein RflaF_01904 n=1 Tax=...   269   9e-71

Sequences not found previously or not previously below threshold:

UniRef50_C1ZED0 CBS domain-containing protein n=1 Tax=Planctomyc...   273   5e-72

>UniRef50_Q5SKB4 Hemolysin-related protein n=3 Tax=Thermus RepID=Q5SKB4_THET8
          Length = 445

 Score =  339 bits (872), Expect = 5e-92,   Method: Composition-based stats.
 Identities = 86/243 (35%), Positives = 144/243 (59%), Gaps = 1/243 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
            + +EL  ++  + ++  I+    +M+  ++++ +  VR+IM PR +M+ ++   TL++ 
Sbjct: 186 VSEEELKLILAGAEESGAIEPQEEEMIHSILELEETPVREIMTPRVEMVAIEDEATLEDL 245

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPESKR 150
           L +  E  +SR PV  E  DHI G+   +DLL +    D +AF +  +      VPE+  
Sbjct: 246 LALYREHRYSRVPVYRESVDHIVGVAYVQDLLTYYCEEDLKAFKVASIAHPPYFVPENMD 305

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH 210
              +LKE R ++ HMAIV+DEFGG +GLVT+ED++E IVGEI DE DE ++   R L   
Sbjct: 306 AWSLLKELRRRKVHMAIVVDEFGGTAGLVTLEDVIEEIVGEIYDESDEPEEHPIRLLPDG 365

Query: 211 TWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
            ++++A   I++ +EA G    + E DT+ G +   FG +P+ GE+++  G++F V  AD
Sbjct: 366 AYSIQAQTPIDEVSEALGVELPEGEYDTLSGFLYALFGRIPSVGESLEWQGFRFVVESAD 425

Query: 271 SRR 273
            RR
Sbjct: 426 QRR 428


>UniRef50_D2DIN9 CBS domain-containing protein n=1 Tax=uncultured Chloroflexi
           bacterium 1i19 RepID=D2DIN9_9CHLR
          Length = 455

 Score =  326 bits (837), Expect = 6e-88,   Method: Composition-based stats.
 Identities = 102/290 (35%), Positives = 165/290 (56%), Gaps = 15/290 (5%)

Query: 6   SHSSDTISNKKGFFSLLLSQLFHGEPKNRDE------------LLALIRDSGQNDLIDED 53
           + S D ++      S+LL +L      + DE            L  LI       +I+ED
Sbjct: 128 ARSVDLVAVVLAPLSILLRRLASSARGDEDEVTAESVFLSEDGLRFLIHVGEGEGVIEED 187

Query: 54  TRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHI 113
            + M+ G+ +  +  VR+IM+PR  ++ ++    L + LD+II + HSR PV  +  DH+
Sbjct: 188 EKQMIAGIFEFGETTVREIMVPRLDIVAVEVTAPLSQALDLIIGNGHSRIPVYEDSIDHL 247

Query: 114 EGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFG 173
            G+L AKDLL  +R  ++  S+ ++LR+A  VP+SK++D + +E ++ R HMA+ +DE+G
Sbjct: 248 LGVLYAKDLLLCLRDGSQDISVRQLLRKAYFVPQSKKLDELFEEMQAHRIHMALAVDEYG 307

Query: 174 GVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD 233
           G +GLVTIED+LE IVGEI+DEYD E+    ++L+   +   A   I++ +       S 
Sbjct: 308 GTAGLVTIEDLLEEIVGEIQDEYDSEEP-QLKKLAPEIYIFNARYDIDEVSRLIDVDLSA 366

Query: 234 --EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
             E +DT+GG +    G +P +GE+I    ++F V   DSRRI +V V+ 
Sbjct: 367 GRENIDTLGGFIYSQLGRVPEQGESIQFKDWRFTVLSVDSRRIEEVRVEP 416


>UniRef50_B8G6A7 Putative uncharacterized protein n=3 Tax=Chloroflexus
           RepID=B8G6A7_CHLAD
          Length = 441

 Score =  324 bits (833), Expect = 2e-87,   Method: Composition-based stats.
 Identities = 83/282 (29%), Positives = 146/282 (51%), Gaps = 4/282 (1%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           ++ +   +L+       E    +++ AL+R+  +   ++   +  ++ V   +D+ VR I
Sbjct: 156 ASTRLILTLIGRANVEEERVTEEDIRALVREGAETGEVEPQEQQFIDRVFRFSDRAVRHI 215

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR ++  ++ N+TL E +D ++ S +SRFPV  E  D I GI+  +DLL   R   E 
Sbjct: 216 MTPRHEVEMVEANRTLGEVIDELLASGYSRFPVYEETPDQIVGIVHVRDLLLLYRKKGEQ 275

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             + + +   + VPE+ R   +L  FR  R HMA+V+ E GG+ G+VT+ED+LE IVGEI
Sbjct: 276 ALVREAVSPPLYVPENSRASALLTTFRRSRRHMALVVGELGGIEGVVTLEDVLEEIVGEI 335

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEE---VDTIGGLVMQAFG 248
           +DEYD+       +    ++ V     +++           DE+    +T+ GLV+   G
Sbjct: 336 DDEYDDATPPPIVRREDGSYLVEGSLPVDEVRALLEVDELPDEDTFRYETLAGLVISLIG 395

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           H+P  G+ +   G++F+V   D  R+ +V +     +  P  
Sbjct: 396 HIPTAGDVVRWSGWRFEVVDMDGLRVDKVLIARDSTTNHPST 437


>UniRef50_D0MD79 CBS domain containing protein n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MD79_RHOM4
          Length = 421

 Score =  324 bits (831), Expect = 3e-87,   Method: Composition-based stats.
 Identities = 95/259 (36%), Positives = 153/259 (59%), Gaps = 6/259 (2%)

Query: 31  PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDE 90
           P + DEL AL  +  Q+ ++ ED R++L  +++  +  VR+IM+ R  ++ +    T  E
Sbjct: 155 PLSPDELKAL--EVAQDGMLGEDERELLAAILEFGETTVREIMVSRLDIVAIPETATFGE 212

Query: 91  CLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM--RSDAEAFSMDKVLRQAVVVPES 148
            L  I  S HSR P+ +E  D+I GI+ AKDLLP++      +  +   + R A+ VP S
Sbjct: 213 VLACIRTSGHSRLPLYAEHLDNILGIVYAKDLLPYLGRAELDQPLNWRDIARPAMFVPLS 272

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           KR+D +L++F+ ++ HMAIV+DE+GG +GLVT+ED+LE IVG+I DE+DE + + + QL 
Sbjct: 273 KRLDDLLRDFQRRKTHMAIVVDEYGGTAGLVTLEDVLEEIVGDIRDEHDETEPVLYEQLD 332

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDE--EVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
            HT+ V A  +++D  E  G     E  + +T+GGL+    G +P  G+ +       +V
Sbjct: 333 EHTYRVDARMNLDDLAELLGIELDTESFDFETLGGLIFHLLGVIPEPGDEVQYGPLHLRV 392

Query: 267 AMADSRRIIQVHVKIPDDS 285
              D+ RI QV V++    
Sbjct: 393 ETVDNHRIGQVLVRVEPTP 411


>UniRef50_B8CXI7 Putative membrane CBS domain protein n=1 Tax=Halothermothrix orenii
           H 168 RepID=B8CXI7_HALOH
          Length = 420

 Score =  323 bits (828), Expect = 7e-87,   Method: Composition-based stats.
 Identities = 85/257 (33%), Positives = 140/257 (54%), Gaps = 2/257 (0%)

Query: 25  QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKR 84
            L   +  + +E+   +  S +  +I  D R M+  + +  D  V++IM+PR  M+ +K 
Sbjct: 153 DLLSSKLLSEEEIKRFVNVSEEEGVIKTDERRMINSIFEFDDTTVKEIMVPRIDMVCIKS 212

Query: 85  NQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVV 144
           +  L E + + ++  HSR PV     D I G++  KDLL ++        +   +R    
Sbjct: 213 DTELSEVIKIAVDRGHSRIPVYKNTIDEIIGVVYVKDLLGYLTKPENDARLADFIRSPYY 272

Query: 145 VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF 204
           VPESK+++ +L E + ++ HMAIV+DE+GG SGLVTIEDILE IVG+I+DEYD E     
Sbjct: 273 VPESKKINELLTEMKKKKVHMAIVLDEYGGTSGLVTIEDILEEIVGDIQDEYDTE-PSQI 331

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
             ++     + A   I+D NE        +E+ +TI G ++   G++P  GE +++DG  
Sbjct: 332 EFINDKELLIDARVDIDDLNEILPEPLPGEEDYETISGFILHYLGYVPKTGEELELDGLH 391

Query: 264 FKVAMADSRRIIQVHVK 280
             V  +   +I +V +K
Sbjct: 392 ILVEESSKHQIKKVRLK 408


>UniRef50_B2I8U5 CBS domain containing protein n=17 Tax=Xanthomonadaceae
           RepID=B2I8U5_XYLF2
          Length = 323

 Score =  321 bits (824), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 128/291 (43%), Positives = 187/291 (64%), Gaps = 5/291 (1%)

Query: 1   MSDDNSHSSDTISN--KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDML 58
           MS+D+ H + T S   ++ +   L S  F G+P   D+L+ ++R +  + +I  DT  M+
Sbjct: 31  MSEDDDHRTITESQEKRRSWLERL-SAAFSGDPHTLDDLMVILRSAEHHGIIATDTLRMM 89

Query: 59  EGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILM 118
           EG + IAD  V D+M+PRSQM++L     L      ++ES HSRFPV  E+KD + GIL+
Sbjct: 90  EGAIAIADLTVGDVMVPRSQMVSLPVESDLQTITKQMVESGHSRFPVHGENKDEVLGILL 149

Query: 119 AKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           AKDLL  + ++    ++ ++LR   ++PESK+++ +LKEFR    HMAIV+DE+GGV+GL
Sbjct: 150 AKDLLRGVSANHTITNVHELLRPVGMIPESKKLNVLLKEFRLSHNHMAIVVDEYGGVAGL 209

Query: 179 VTIEDILELIVGEIEDEYDEEDDID--FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEV 236
           VTIEDILE IVG+I+DE+DE +D        +   + V AL  IEDFNE F   F D++ 
Sbjct: 210 VTIEDILEQIVGDIDDEHDETEDQTNMIAIQADGCYIVDALTPIEDFNERFNAEFPDDDY 269

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           DTIGGLV +A GHLP  G+ + I  + F+VA A++RRI  +HV +   + Q
Sbjct: 270 DTIGGLVTEAIGHLPETGDELTIGRFAFRVAKANARRIHILHVTVLPPNEQ 320


>UniRef50_B8I559 Putative uncharacterized protein n=1 Tax=Clostridium cellulolyticum
           H10 RepID=B8I559_CLOCE
          Length = 434

 Score =  321 bits (824), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 81/276 (29%), Positives = 150/276 (54%), Gaps = 10/276 (3%)

Query: 18  FFSLLLSQLFHGEP-------KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           F +    ++F G P          +E+  ++    +  +I +  ++M++ + +  ++ V 
Sbjct: 159 FSTNFFIKVFGGNPAGGDDEKVTEEEIRMMMEVGEERGVIQDTEKEMIDNIFEFDNKSVS 218

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           +IM  R+ ++ +  +  ++  L ++    ++R P+ +++ D+I GIL  KDLL + +S  
Sbjct: 219 EIMTHRTNIVGIPVDSDINYVLYIMNRDKYTRVPIYNDNIDNIVGILHVKDLLEYTQSHN 278

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           + FS+ K++R A  VPESKR D + KE +  + H+A+VIDE+GG +G+VTIED+LE IVG
Sbjct: 279 KDFSLKKIIRSAYFVPESKRTDELFKEMQKNKVHLAVVIDEYGGTAGIVTIEDLLEEIVG 338

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
            I DEYD E   D   L  +T+       ++   E        ++ DT+GG +++  G +
Sbjct: 339 NIFDEYDIE-QKDIEYLENNTYIFDGAIDLDKVEEVLDEDLPVDDFDTLGGFILKLLGRI 397

Query: 251 PARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           P   E  T+  +   FKV   + +RI++V     ++
Sbjct: 398 PKVDEKPTVPYENIVFKVVKMEGKRIVKVQASKQEN 433


>UniRef50_Q1AX40 Putative uncharacterized protein n=1 Tax=Rubrobacter xylanophilus
           DSM 9941 RepID=Q1AX40_RUBXD
          Length = 442

 Score =  319 bits (819), Expect = 6e-86,   Method: Composition-based stats.
 Identities = 89/258 (34%), Positives = 145/258 (56%), Gaps = 1/258 (0%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  + +EL  +I  S  + ++D + RD L  V D  D+  R++M+PR  ++ L  + +  
Sbjct: 182 EVHSEEELRIMISSSAASGVLDPEERDYLNNVFDFGDRVAREVMVPRPDIVALSSDLSPQ 241

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
           E +       ++R+PV   D DH+ G++  KD+          F + K++R A+VVPE+K
Sbjct: 242 EMVQEAAFGRYTRYPVYEGDLDHVLGVVHVKDIFRASLESPGGFDVRKIVRDALVVPENK 301

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            ++++L+EF+ ++  MAIVIDE+G V GLVTIED+LE IVGEI+DE+DEE+     +L  
Sbjct: 302 PIEQLLREFQRRKLQMAIVIDEWGSVEGLVTIEDVLEEIVGEIQDEFDEEE-ARIEELGG 360

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
             + V     I + NE F      E+ +TIGG V+   G  P  G+ ++ DG   +V   
Sbjct: 361 GLYAVDGRIPIVEVNEFFELDLPHEDFETIGGYVLGTLGRPPRPGDVVEADGATLQVKSV 420

Query: 270 DSRRIIQVHVKIPDDSPQ 287
           D  R+  + ++  + SP 
Sbjct: 421 DGPRVSMLTLRRKERSPS 438


>UniRef50_Q3A2F6 Uncharacterized CBS domain-containing protein n=2
           Tax=Desulfuromonadales RepID=Q3A2F6_PELCD
          Length = 417

 Score =  319 bits (819), Expect = 7e-86,   Method: Composition-based stats.
 Identities = 100/273 (36%), Positives = 168/273 (61%), Gaps = 5/273 (1%)

Query: 19  FSLLLSQLFHGEP---KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           FS LL+     EP    + +E+  LI    Q+ ++ +D R ML+G+ D++   VRD+MIP
Sbjct: 147 FSRLLTLFVKSEPQPVISEEEIRTLITVGEQSGVVGKDKRKMLDGIFDLSQICVRDVMIP 206

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R+++  L  + +  E L ++ +S+HSRFP+     D++ GI+ +KD+L ++   +E FS+
Sbjct: 207 RTEIAALDVSFSFAEVLRLVQQSSHSRFPIYEGSLDNVIGIIHSKDILRYVHI-SEEFSL 265

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
           +K+ R+   VPESKR++ +L  F+ ++ HMA+V+DE+GGV GLVT+ED++E IVGEI DE
Sbjct: 266 EKLARKPYFVPESKRINTLLPAFQRRQVHMAVVVDEYGGVEGLVTLEDVVEEIVGEIRDE 325

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
           YD ++D+   +L    + + A  S+   N+ FG   S+E   T+ G ++   G +P  G+
Sbjct: 326 YDIDEDM-VCELRPGRYLLDASISLRAVNQRFGLELSEEHASTLAGFLLGVLGSIPRVGD 384

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           + ++D   F V      RI ++ + +P DSP P
Sbjct: 385 SCEVDKSHFIVRKVIHHRIEEIELLLPPDSPDP 417


>UniRef50_A9WFQ5 CBS domain containing protein n=4 Tax=Chloroflexaceae
           RepID=A9WFQ5_CHLAA
          Length = 450

 Score =  319 bits (819), Expect = 7e-86,   Method: Composition-based stats.
 Identities = 94/272 (34%), Positives = 143/272 (52%), Gaps = 2/272 (0%)

Query: 15  KKGFFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
            +  F+LL  Q     P    +EL  ++    +   I+ + R+M+EGVMD  D  VR+IM
Sbjct: 153 TRPIFTLLSGQPAPPTPLVTEEELRLMMSAGEKAGWIEHEEREMIEGVMDFGDTLVREIM 212

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR  ++ L+ N  L   LDV I   HSR PV  E  D++ GIL  KDL+P +R      
Sbjct: 213 IPRVDVVALEVNSPLKRALDVAITRGHSRIPVYEETIDNVVGILYVKDLIPVLRDGKHDT 272

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            +  +LR A  VP + +V  +L++ + +R HMAIV+DE+GG +G+VT+ED++E IVGEI 
Sbjct: 273 PLRDLLRPAYFVPVTMKVAALLEDLQRRRVHMAIVVDEYGGTAGIVTLEDLIEQIVGEIR 332

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DEYD E+     ++  +   V A   I+D        F +   D IGGLV +  G +P  
Sbjct: 333 DEYDTEEPA-IVEVGPNELIVDARVPIDDVAGLLEVEFPETTADRIGGLVYEQLGRIPRE 391

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           G+ +  +     V      R  ++ +     +
Sbjct: 392 GDQVVCNDVTITVLSIKGIRAERLRIVRQAPA 423


>UniRef50_D1CDD2 CBS domain containing protein n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CDD2_THET1
          Length = 434

 Score =  318 bits (817), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 99/271 (36%), Positives = 156/271 (57%), Gaps = 3/271 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           +  +        D+L  L+    +  +I+++ RDM+ G++   D    ++M+PR  ++ +
Sbjct: 162 VKDMPRNPFITEDDLRMLVNAGEEEGVIEQEERDMIAGILRFGDIAAHEVMVPRPDIVAV 221

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQA 142
             N  L   LD+ +E  HSR PV  E  D++ GI+  KDL   + S +   S+  + R A
Sbjct: 222 DVNTDLRTALDLALEKGHSRLPVYEESLDNVVGIVYLKDLARAIVS-SSNVSLRDLARPA 280

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
           V +PESKR+  +L+EF+S + HMAIV+DE+GG +GL+TIEDILE IVGEI+DEYD E   
Sbjct: 281 VFIPESKRLGELLQEFQSSKVHMAIVVDEYGGTAGLITIEDILEEIVGEIQDEYDVELP- 339

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGY 262
           D  ++S   W +RA   ++D NE  G H   EE DT+GG +      LP  G+ ++++G 
Sbjct: 340 DIEKISEDEWIIRAKIDLDDVNELLGIHLPAEEYDTLGGFITAQLERLPVPGDEVEVEGV 399

Query: 263 QFKVAMADSRRIIQVHV-KIPDDSPQPKLDE 292
             KV   + RR+ +V V ++P  +     +E
Sbjct: 400 LMKVLDIEKRRVGRVLVKRLPVPTTSENQEE 430


>UniRef50_Q9KTE3 Magnesium and cobalt efflux protein corC n=42 Tax=Proteobacteria
           RepID=CORC_VIBCH
          Length = 291

 Score =  318 bits (817), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 189/283 (66%), Positives = 234/283 (82%), Gaps = 2/283 (0%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M++DNS +S+  S +K FF  L SQLF GEPK+R EL+ +IRDS  NDLID DTRDMLEG
Sbjct: 1   MNEDNSQNSEGPS-RKSFFERL-SQLFQGEPKDRQELVDVIRDSEVNDLIDHDTRDMLEG 58

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           VM+IA+ RVRDIMIPRSQM+T+ R   LD  + ++ ++ HSR+PVISEDKDH+EGIL+AK
Sbjct: 59  VMEIAEMRVRDIMIPRSQMVTIDRTHNLDALVAIMTDAQHSRYPVISEDKDHVEGILLAK 118

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL ++ S+   F++ +V+R AVVVPESKRVDR+LKEFR +RYHMAIV+DEFGGVSGLVT
Sbjct: 119 DLLKYLGSNCAPFNIQEVIRPAVVVPESKRVDRLLKEFREERYHMAIVVDEFGGVSGLVT 178

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IEDILE IVG+IEDE+D+E+  D RQLS+HT++V+AL +IEDFN  FGT FSDEEVDT+G
Sbjct: 179 IEDILEEIVGDIEDEFDDEEQKDIRQLSKHTFSVKALTTIEDFNHTFGTKFSDEEVDTVG 238

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           GLVM AFGHLPARGE +DI GY FKV  ADSRR++ + V +PD
Sbjct: 239 GLVMTAFGHLPARGEVVDIAGYNFKVTAADSRRVVALQVTVPD 281


>UniRef50_B7IDY0 Integral membrane protein with CBS domains n=4 Tax=Thermotogaceae
           RepID=B7IDY0_THEAB
          Length = 430

 Score =  318 bits (817), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 87/257 (33%), Positives = 151/257 (58%), Gaps = 4/257 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              ++++  +    +   I  +   ML+  +++ +  VR+IMIPR  ++ ++ ++TLD+ 
Sbjct: 172 ITTEDIIMYVEVGREEGTIKHEESFMLKRTLEMEESVVREIMIPRVDIVAIEESETLDKV 231

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA----EAFSMDKVLRQAVVVPE 147
           +++I E  +SR PV  E  D++ GI  AKD+L F+        E   + +++R+ + VPE
Sbjct: 232 MEIIKEEEYSRIPVYKETIDNVVGICYAKDVLAFISDRGSEICEKVKVKELMREPLFVPE 291

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           + +V  +LK F+ Q+ HMAIV+DE+GG +GLVT+EDILE I GEI DEYD+ +++  ++L
Sbjct: 292 TMKVSELLKIFKEQKMHMAIVVDEYGGTAGLVTMEDILEEIFGEIMDEYDQNENLGIKKL 351

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
              ++ V A   I D        F + + +T+ G +++    +P  GE I ID ++FK+ 
Sbjct: 352 ENGSYIVDATVPINDIERELKIEFPETDYETLAGYILEHLQRIPKVGEEIIIDKFKFKII 411

Query: 268 MADSRRIIQVHVKIPDD 284
            A   RI +V VK+  D
Sbjct: 412 AASKNRIEKVLVKVVKD 428


>UniRef50_C1SMP1 CBS domain-containing protein n=1 Tax=Denitrovibrio acetiphilus DSM
           12809 RepID=C1SMP1_9BACT
          Length = 434

 Score =  317 bits (813), Expect = 3e-85,   Method: Composition-based stats.
 Identities = 105/262 (40%), Positives = 153/262 (58%), Gaps = 3/262 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              DEL   I +S +  +I+     ML+ + DI++  V+++M+PR+ M+ +     ++  
Sbjct: 166 ITEDELEFYICESEKEGIIENGKSRMLQNIFDISEIYVKEVMVPRTDMVAIDIEDPVESY 225

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           +D I  S  SR PV  E  D I GIL  KDLL F+  D+  F + KVLR+   +PE+K++
Sbjct: 226 IDKIHASEFSRIPVYEETIDKIIGILYVKDLLRFVNEDSTQFDLRKVLRKPYFIPETKKI 285

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D ML EF+  R HMAIVIDE+GGV GLVT+EDILE IVGEI DEYD E+  +  ++S +T
Sbjct: 286 DSMLSEFQRNRNHMAIVIDEYGGVDGLVTLEDILEEIVGEIWDEYDTEEQ-EVTEISENT 344

Query: 212 WTVRALASIEDFNEAFGTH--FSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
           + V     I+DF E FG       +E +T+GGLV      +P  GE    + YQFK+   
Sbjct: 345 FIVDVRMDIDDFCEKFGLEKTHEMDEYETVGGLVFDIAEKIPEVGEQYVYENYQFKILNK 404

Query: 270 DSRRIIQVHVKIPDDSPQPKLD 291
             RR+ +V ++  +  P  K +
Sbjct: 405 HERRLDKVELRRIEKEPDEKQE 426


>UniRef50_B0PAE4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0PAE4_9FIRM
          Length = 472

 Score =  316 bits (811), Expect = 5e-85,   Method: Composition-based stats.
 Identities = 83/276 (30%), Positives = 150/276 (54%), Gaps = 10/276 (3%)

Query: 22  LLSQLFHG------EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           LLS+LF        E    +E+  ++    +   I++  +DM+  + +  D+ V ++M  
Sbjct: 196 LLSRLFGARGGDETERVTEEEIRMMVDVGNEKGAIEQSEKDMINNIFEFDDRNVSEVMTH 255

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R+ M  + ++ T+D  + + IE+  SR PV  ED D I GI+  KDLL  + +    F  
Sbjct: 256 RTDMTAVPKDVTIDRIVAIAIETGFSRIPVYDEDIDDIMGIVYVKDLLCLIGTPGVDFDA 315

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
            K +R A+ VPES     +  +F+ ++  +AIV+DE+GG +G+ ++ED+LE IVG I+ +
Sbjct: 316 QKYMRPALFVPESMSCVDLFAQFKQKKVMVAIVVDEYGGTAGIASMEDLLESIVGNIQ-D 374

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARG 254
             +++D +  ++S   +T+    SIED    F     ++ E DTIGGL+++    +P+  
Sbjct: 375 EYDDEDEEICKMSDGVYTLDGAVSIEDVERLFDIELDEDSEYDTIGGLLIEKLERIPSPH 434

Query: 255 ET--IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           E   +++ G +F V + + RRI ++  + P    Q 
Sbjct: 435 EHPALELSGVRFTVLLVEDRRIARIRAEKPSAPGQE 470


>UniRef50_A4VQY6 Metal ion transporter, putative n=2 Tax=Gammaproteobacteria
           RepID=A4VQY6_PSEU5
          Length = 280

 Score =  315 bits (808), Expect = 1e-84,   Method: Composition-based stats.
 Identities = 139/286 (48%), Positives = 198/286 (69%), Gaps = 7/286 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S     IS +K +    ++Q F  EPKNR ELL ++R++ QN L+D +   ++EG
Sbjct: 1   MSEDRS-----ISGQKTWLER-ITQAFAHEPKNRQELLEILREAHQNKLLDNEALAIVEG 54

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            + +AD +VRDIM+PRSQ+I++K +Q+  E L  II +AHSR+PV+ E  D + G+L+AK
Sbjct: 55  AIQVADLQVRDIMVPRSQVISIKADQSPREFLPAIIAAAHSRYPVVGESLDEVIGVLLAK 114

Query: 121 DLLPF-MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLLP  ++ D + F +  +LR A  VPESKR++ +L+EFR+   HMAIVIDE+GGV+GLV
Sbjct: 115 DLLPLILKEDQQNFDIKDLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLV 174

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVG+IEDE+D E+D   R L    + V+AL  I+ FNE FG+ F D+E DT+
Sbjct: 175 TIEDVLEQIVGDIEDEHDVEEDSYIRPLPSGDFLVKALTPIDSFNEYFGSAFPDDEFDTV 234

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            GLVM  FGHLP R E  +IDG++ +V  ADSRR+  + +   + +
Sbjct: 235 AGLVMSTFGHLPKRNEVTEIDGFRVRVLNADSRRVHMLRLSRLESA 280


>UniRef50_C7IJK2 CBS domain containing protein n=5 Tax=Firmicutes RepID=C7IJK2_9CLOT
          Length = 377

 Score =  314 bits (805), Expect = 2e-84,   Method: Composition-based stats.
 Identities = 85/275 (30%), Positives = 146/275 (53%), Gaps = 5/275 (1%)

Query: 14  NKKGFFSLLLSQLFHG--EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +   F  L       G  E    +E+  ++    +  +I +  ++M++ + +  ++ V +
Sbjct: 103 STNFFIKLFGGNPAGGDDEKVTEEEIRMMMEVGEERGVIQDSEKEMIDNIFEFDNKHVSE 162

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM  R+ +  +  +  L+  L V+    ++R PV SE+ D+I GIL  KDLL + +++A+
Sbjct: 163 IMTHRTDIDGIPVDSDLEYVLYVMNRDKYTRVPVYSENLDNIVGILHVKDLLEYTQNNAK 222

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            FS++K+ R A  VPESKR D + KE +  + H+A+VIDE+GG +G+VTIED+LE IVG 
Sbjct: 223 DFSLEKITRSAYFVPESKRTDELFKEMQKNKVHLAVVIDEYGGTAGIVTIEDLLEEIVGN 282

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DEYD E   D   L   T+      S++   E        ++ DT+GG +++  G +P
Sbjct: 283 IFDEYDIE-QKDIEYLENDTYVFDGAISLDRVEEVLDEELPVDDFDTLGGFILKLLGRIP 341

Query: 252 ARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
              E   +  +   F+V   +  RI +V     ++
Sbjct: 342 KVDEKPVVQYENIVFRVTEMEGMRIAKVQASKKEN 376


>UniRef50_A7NHB2 CBS domain containing protein n=1 Tax=Roseiflexus castenholzii DSM
           13941 RepID=A7NHB2_ROSCS
          Length = 435

 Score =  314 bits (805), Expect = 3e-84,   Method: Composition-based stats.
 Identities = 103/277 (37%), Positives = 164/277 (59%), Gaps = 10/277 (3%)

Query: 17  GFFSLLLSQLFHGEP------KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           G  +    ++  G+          +EL  L+    +  LI+ + R+M+EG+    D  VR
Sbjct: 145 GLLTRPFLRVASGQTTSSMPLVTEEELRMLVNVGEEEGLIEPEEREMIEGIFSFGDTTVR 204

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           ++MIPR  ++ L+   ++DE L++II + HSR PV  E  DHI GIL AKDLL ++RS  
Sbjct: 205 EVMIPRVDIVALEETASIDEALNIIITTGHSRIPVYRETIDHIVGILYAKDLLLWLRSGQ 264

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
              S+  +LR A  VP++ +VD +LK+ ++++ H+AIV+DE+GG +GL+TIED++E IVG
Sbjct: 265 RDASIGALLRTAHFVPDTMKVDALLKDLQARKIHLAIVVDEYGGTAGLITIEDVIEEIVG 324

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           EI+DEYD ++    R L+     V A   I+D N+  G   + EE D IGG+V +  G +
Sbjct: 325 EIQDEYDVDEQP-IRVLAPGDMEVDARVPIDDINDLTGLRLASEESDRIGGMVFERLGRV 383

Query: 251 PARGETIDI-DGYQFKVAMADSRRIIQVHV--KIPDD 284
           P  G+T+ I DG    V   D  R+ ++ +  ++P +
Sbjct: 384 PKVGDTVQIADGVTVVVLSMDGLRLRKLRLQYRLPQE 420


>UniRef50_D1N3F2 Putative uncharacterized protein n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N3F2_9BACT
          Length = 445

 Score =  313 bits (804), Expect = 4e-84,   Method: Composition-based stats.
 Identities = 81/281 (28%), Positives = 140/281 (49%), Gaps = 3/281 (1%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           ++      L    L + +    +E+  ++    +N  I+ D + M+E V +  +    ++
Sbjct: 166 ASVNFVLRLFGVTLGNSQEVTEEEIRMMVDIGEENGAIESDEKRMIENVFEFNNTTAAEV 225

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M  R++M+ L      +E   V++    SR PV  ED D I G L  ++ L        A
Sbjct: 226 MTHRTEMVALDIEAPPEEVEKVLMSCGFSRVPVYREDIDEIIGFLHFREYLSAKVQGNSA 285

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             + K+L+   + PE+ R + + +  +S+++ MAI++DEFGG SGLVTIED+LE IVG +
Sbjct: 286 PDIRKLLKPVYLAPETMRANILFRNMQSKKFGMAIILDEFGGTSGLVTIEDLLEEIVGSL 345

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DEYDE D I+  QL    W +     +++ +        +EE DTIGGLV      +P 
Sbjct: 346 YDEYDEAD-IEIEQLGEGEWRIDGSMRLDEISRRLDLALPEEEYDTIGGLVFGMLNEVPT 404

Query: 253 RGETID--IDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
            G T++  + G   +V   + RR+ +V ++      +   +
Sbjct: 405 VGATVELPVSGISIRVESVEERRVDKVILQYTPPQEEESGE 445


>UniRef50_A5UY55 Putative uncharacterized protein n=3 Tax=Chloroflexi (class)
           RepID=A5UY55_ROSS1
          Length = 479

 Score =  313 bits (802), Expect = 6e-84,   Method: Composition-based stats.
 Identities = 88/284 (30%), Positives = 152/284 (53%), Gaps = 10/284 (3%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           + +    LL        P   D+++AL+R+   +  + +  + ++  V   +D+ VR +M
Sbjct: 177 STEVVLRLLGRHNVAEMPVTEDDIMALVREGAADGTVADAEQTVIHNVFKFSDRTVRSLM 236

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR+Q+  L  +  ++E L +  ES +SR PV     DH+ GIL  KDLL F     E  
Sbjct: 237 TPRTQITALDVDTPIEEALRIATESGYSRIPVYEGSLDHVIGILYVKDLLAFW-GQCEPP 295

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           ++ ++LR  + V ES+R  +  ++ +  R  +AIV+DE+G V+G++TIED+LE +VG+I 
Sbjct: 296 NLRELLRPPMYVIESQRAAQAFQQLKQNRNALAIVLDEYGQVAGVITIEDMLEELVGDIS 355

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-----EVDTIGGLVMQAFG 248
           DEYD+E D    +    ++ V  L    D  E      +D+       +T+ G ++   G
Sbjct: 356 DEYDDETDESIVRRDDGSYLVDGLTPFADLRERLKLPPADDLVREHGFETLAGFLLALLG 415

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            +PA G+++  +GY F++   D RRI +V V      P+P +D+
Sbjct: 416 RIPAVGDSVKWEGYSFEIVDMDGRRIDKVLVV----PPRPAVDQ 455


>UniRef50_Q48DN5 Metal ion transporter, putative n=16 Tax=Proteobacteria
           RepID=Q48DN5_PSE14
          Length = 280

 Score =  313 bits (802), Expect = 7e-84,   Method: Composition-based stats.
 Identities = 143/282 (50%), Positives = 199/282 (70%), Gaps = 7/282 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S +      +K +   L +Q F  EPKNR ELL L+R++ QN L+D +   ++EG
Sbjct: 1   MSEDRSSNG-----QKSWLGKL-TQAFVHEPKNRQELLELLREAHQNKLLDSEALAIVEG 54

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            + +AD +VRDIM+PRSQMI++K  QT  E L  +I++AHSR+PVI E  D + G+L+AK
Sbjct: 55  AIQVADLQVRDIMVPRSQMISIKATQTPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAK 114

Query: 121 DLLPF-MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLLP  +++D ++  + K+LR A  VPESKR++ +L+EFR+   HMAIVIDE+GGV+GLV
Sbjct: 115 DLLPLILKADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLV 174

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVG+IEDE+D E+D   + L    + V+AL  +E+FNE F + FSD+E DT+
Sbjct: 175 TIEDVLEQIVGDIEDEHDVEEDSYIKPLPSGDFLVKALTPVENFNEFFDSAFSDDEFDTV 234

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           GGLVM AFGHLP R E  +I  Y+F++  ADSRRI  + V  
Sbjct: 235 GGLVMNAFGHLPKRNEITEIGAYRFRILSADSRRIHLLRVTP 276


>UniRef50_D0KZZ4 CBS domain containing protein n=1 Tax=Halothiobacillus neapolitanus
           c2 RepID=D0KZZ4_HALNC
          Length = 299

 Score =  312 bits (800), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 126/282 (44%), Positives = 182/282 (64%), Gaps = 5/282 (1%)

Query: 5   NSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDI 64
           +  SS + S++ G+F+ L  Q    + K+  ++L + + + +  +I   T  +++ V++ 
Sbjct: 2   DEDSSPSRSDEPGWFARLRQQWCISQVKSCSDILTVAKAAAEKQIIPHSTASLIDSVLEF 61

Query: 65  ADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP 124
            D RVRD+MIPR QM  +    TL + L  I E+ HSR+PVI E++D I GIL+ K+LL 
Sbjct: 62  HDSRVRDVMIPRGQMDVINITSTLPQILSEIAETGHSRYPVILENRDEITGILLVKELLH 121

Query: 125 FMR-----SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           F        D   F++   +R A+ VPESKR+D +L EFR  R HMAIV+DEFGGV+GLV
Sbjct: 122 FYAGTPSEEDIAGFTLKNHIRSALYVPESKRLDVLLAEFRLTRTHMAIVLDEFGGVAGLV 181

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVG+I+DEYD  + +  R+ S + +TVRAL  I++FN  FGT FSD+E DTI
Sbjct: 182 TIEDVLEEIVGDIDDEYDTAEPVHIREQSANRFTVRALTPIDEFNAHFGTDFSDDEYDTI 241

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           GG +    GHLP RGE + + GY+FK+  AD RR+  + V +
Sbjct: 242 GGFITHELGHLPRRGEVVCVGGYEFKILGADKRRLHLLLVTV 283


>UniRef50_Q3JVV5 Magnesium and cobalt efflux protein CorC n=105 Tax=Proteobacteria
           RepID=Q3JVV5_BURP1
          Length = 403

 Score =  312 bits (800), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 124/284 (43%), Positives = 184/284 (64%), Gaps = 6/284 (2%)

Query: 1   MSD--DNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDML 58
           M+D   +  SSD    K+     L + +   EP +R ELL +++D+ + +LID D+  M+
Sbjct: 109 MNDSYPSRKSSDKPHEKRSLLERL-TDIISPEPDSRAELLEILQDAHERNLIDADSLSMI 167

Query: 59  EGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILM 118
           EGV  ++D   RDIM+PR+QM  L      ++ +  ++E AHSR+PV  +++D++ G+L+
Sbjct: 168 EGVFQVSDLCARDIMVPRAQMDALNIADKPEDFIPFVLEKAHSRYPVYEDNRDNVIGVLL 227

Query: 119 AKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           AKDLL F     E F +  +LR AV +PESKR++ +L +FR  R H+AIV+DE+GGV+GL
Sbjct: 228 AKDLLRFYAE--EEFDVRGMLRPAVFIPESKRLNVLLHDFRVNRNHLAIVVDEYGGVAGL 285

Query: 179 VTIEDILELIVGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           +TIED+LE IVG+IEDEYD +E+  +        + VRAL  IE FNE FGT FSD+EVD
Sbjct: 286 ITIEDVLEQIVGDIEDEYDFDEEAGNIIAAPDGRYRVRALTEIEQFNETFGTDFSDDEVD 345

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           TIGGL+   FG +P RGE + +    F++   D+R+I  + V+ 
Sbjct: 346 TIGGLITHHFGRVPHRGEKVRLGELLFEIQRGDARQIHVLLVRR 389


>UniRef50_A7HLR9 Putative uncharacterized protein n=1 Tax=Fervidobacterium nodosum
           Rt17-B1 RepID=A7HLR9_FERNB
          Length = 443

 Score =  311 bits (798), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 99/297 (33%), Positives = 159/297 (53%), Gaps = 13/297 (4%)

Query: 9   SDTISNKKGFF---SLLLSQLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLE 59
           S  +S    FF   S    +LF G+          D++ + +    +   ID +   M+E
Sbjct: 137 SKLLSPLVSFFVTVSNYFVKLFGGQKVAEAPFITMDDIASYLEMGREEGTIDHEEGLMVE 196

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
             + + +  V++IMIPR  ++ ++  QTL E ++VIIE  +SR PV  +  D++ GI  A
Sbjct: 197 RTIAMDETLVKEIMIPRIDVVAVEETQTLGEVINVIIEEEYSRIPVYRDTIDNVVGICYA 256

Query: 120 KDLLPFMRSDA----EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGV 175
           KD+L F+            + +++R  + VPE   V  +LKEF+S++ HMAIV+DE+GG 
Sbjct: 257 KDILSFIAQRGSDVMNKVRVKELMRPPLFVPEVMPVSELLKEFKSKKVHMAIVVDEYGGT 316

Query: 176 SGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE 235
           +G+VT+EDILE I GEI DEYDE +    ++L   T+ V A  S+ D        F + E
Sbjct: 317 AGIVTMEDILEEIFGEIMDEYDEHESTGIKKLDDFTYLVDATLSLNDIERELRIEFPEGE 376

Query: 236 VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            +T+ G ++  F H+P  GE  +     +KV  A   RI +V +KI  D  + + ++
Sbjct: 377 FETLAGYLLDKFHHIPKVGEQYEDSNITYKVVAASRNRIEKVLMKINVDIDKEEKND 433


>UniRef50_Q1IYV3 CBS domain-containing protein DUF21 n=4 Tax=Bacteria
           RepID=Q1IYV3_DEIGD
          Length = 446

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 82/263 (31%), Positives = 141/263 (53%), Gaps = 3/263 (1%)

Query: 10  DTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           + + N       L     H    + +E+  ++  S Q  ++++D ++++  V D+++  V
Sbjct: 158 NALGNGVVRLFGLQGVAGHHTAYSEEEIRMIVSASSQEGVLEDDEKELVYNVFDLSETTV 217

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           R++M PR++M+T++    L   L++  E  +SR PV  +  D++ G+    D+L ++   
Sbjct: 218 REVMTPRTEMVTVEATCPLRRLLELNAEHGYSRVPVYQDSADNVVGVAHTSDVLRYLDRL 277

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            E   +  V+     VPE  +++ +L + R ++ HMAIV+DEFGG SGLVT+ED LE IV
Sbjct: 278 DETL-IADVMHPVFFVPEGMKINDLLAKMREKKSHMAIVVDEFGGTSGLVTLEDALEEIV 336

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD--EEVDTIGGLVMQAF 247
           GEI DE DEE+      L    + + A  ++ +  E  GT+  D   E DT+ G +   F
Sbjct: 337 GEIYDETDEEEQPLIEVLGEGIYLMDASLTVGEVEERLGTNLEDGEGEYDTLSGFMTSHF 396

Query: 248 GHLPARGETIDIDGYQFKVAMAD 270
           G +P  G++    G+ F V  AD
Sbjct: 397 GDIPEIGQSFVYGGWAFTVVDAD 419


>UniRef50_C7GAD7 CBS domain protein n=9 Tax=Bacteria RepID=C7GAD7_9FIRM
          Length = 426

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 93/278 (33%), Positives = 146/278 (52%), Gaps = 9/278 (3%)

Query: 19  FSLLLSQLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           FS+    L H +PK        +EL  ++  S +N +I+ +  +M+  + D  D + +++
Sbjct: 148 FSMGFLFLLHVDPKANNNQMTEEELRTIVDVSKENGVIESEEHEMINNLFDFGDAQAKEV 207

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           MIPR  M     N T DE +D+  E   +R PV  +  D++ GIL  KDLL  +  D E 
Sbjct: 208 MIPRPDMTFANVNNTYDELIDIFQEDKFTRLPVYEDTTDNVIGILNMKDLL--LCKDKEH 265

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
           FS+  ++R+     E K    +  E R     +AIV+DE+G  +GL+T+ED+LE IVGEI
Sbjct: 266 FSVRDIMREPYFTFEHKNTAELFIEMRKSSISLAIVLDEYGATAGLITLEDLLEEIVGEI 325

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DEYD +++     L+   + V    +++D  +    +FS E+ DTIGG ++    HLP 
Sbjct: 326 RDEYDTDEEDPILPLNDREFIVSGSTNLQDLCDELDLNFSSEDYDTIGGYLLGLLDHLPE 385

Query: 253 RGETIDI-DGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           + E I   D    +V   D  RI +V++K PD  P   
Sbjct: 386 KNEIIITDDNVLLRVEQMDKNRIEKVYIKKPDFPPDES 423


>UniRef50_Q9CM13 Magnesium and cobalt efflux protein corC n=264
           Tax=Gammaproteobacteria RepID=CORC_PASMU
          Length = 300

 Score =  310 bits (796), Expect = 3e-83,   Method: Composition-based stats.
 Identities = 181/280 (64%), Positives = 231/280 (82%), Gaps = 1/280 (0%)

Query: 5   NSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDI 64
           N++S+++   KK FF  L  + F GE KNR+EL+ +IRDS QN+LID++TR+M+EGVM+I
Sbjct: 8   NTYSTES-HQKKSFFQSLFGRFFQGELKNREELVEVIRDSEQNELIDQNTREMIEGVMEI 66

Query: 65  ADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP 124
           A+ RVRDIMIPRSQ++ +  +Q LD CLD II SAHSRFPVI++++D+I GIL AKDLL 
Sbjct: 67  AELRVRDIMIPRSQIVFIHTDQNLDSCLDTIIVSAHSRFPVITDERDNIAGILHAKDLLR 126

Query: 125 FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDI 184
           F+RS+AE F +  +LR AV+VPESKRVDRMLK+FRS+R+HMAIV+DEFG VSGLVTIEDI
Sbjct: 127 FLRSNAEEFDLMPLLRPAVIVPESKRVDRMLKDFRSERFHMAIVVDEFGAVSGLVTIEDI 186

Query: 185 LELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVM 244
           LE IVG+IEDE+DEE+ ++ RQLSRHT+ VRAL  IEDFN+ F THF+DEEVDTIGG+VM
Sbjct: 187 LEQIVGDIEDEFDEEEIVNIRQLSRHTYAVRALTDIEDFNQQFNTHFADEEVDTIGGVVM 246

Query: 245 QAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           QAFG+LP RGE I I+   FKV  ADSRR+IQ+ + + D+
Sbjct: 247 QAFGYLPKRGEEITIENIGFKVTSADSRRLIQLRITVTDE 286


>UniRef50_B7J5B5 Magnesium and cobalt efflux protein, putative n=2
           Tax=Acidithiobacillus ferrooxidans RepID=B7J5B5_ACIF2
          Length = 291

 Score =  310 bits (796), Expect = 3e-83,   Method: Composition-based stats.
 Identities = 120/290 (41%), Positives = 181/290 (62%), Gaps = 5/290 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S    +    +G++    +Q   G  +++D LL LIR++G+  +ID +T  M++G
Sbjct: 1   MSEDRS----SQERPRGWWER-FTQSLRGNVEDQDTLLELIREAGERQIIDAETARMVDG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           +  + +  VRD+MIPR+QM  ++ +  L E +  + E  HSRFPV+  D+D + GIL+AK
Sbjct: 56  IFRMGELTVRDVMIPRAQMEVIELDMPLAEIIARVSEVGHSRFPVVGHDRDDVRGILLAK 115

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL   R D  A  +  +LR A  +PESK +D +L EFR+ R+HMA+V+DE+GGV+GL+T
Sbjct: 116 DLLRGCRGDVPALRLTDLLRPATFIPESKHLDHLLYEFRTGRHHMAVVVDEYGGVAGLIT 175

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IED+LE+IVGEIEDEYD ++D+         + V AL  +E+FN  F TH  D   DT+G
Sbjct: 176 IEDVLEIIVGEIEDEYDIDEDVMIAPREDGDFLVNALIPLEEFNAHFVTHLEDGHADTLG 235

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           G V  A GH+P  GE ++    + +V  AD +R+  + V  P  +P P+ 
Sbjct: 236 GWVAAALGHVPRTGEVVEEGDLRLEVLRADRKRVQILRVTPPRGAPLPET 285


>UniRef50_Q7VRA4 Haemolysin-related protein n=2 Tax=Candidatus Blochmannia
           RepID=Q7VRA4_BLOFL
          Length = 291

 Score =  309 bits (793), Expect = 6e-83,   Method: Composition-based stats.
 Identities = 163/284 (57%), Positives = 221/284 (77%), Gaps = 2/284 (0%)

Query: 4   DNSHSSDTISN--KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGV 61
           +N++  ++I +  KK FF+L+L  LF    +NR++LL LIRD  +N LID DT+DMLEGV
Sbjct: 2   NNNYLEESIHSVRKKNFFALILKHLFRENFRNRNDLLNLIRDFEKNALIDSDTKDMLEGV 61

Query: 62  MDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKD 121
           ++I +Q+VRDIMIPRSQ+I LK  Q+ DE L +II+S+HSRFPV++ED D I+GIL+AKD
Sbjct: 62  LEIVEQKVRDIMIPRSQIIFLKNTQSWDEQLSIIIQSSHSRFPVLNEDLDQIKGILIAKD 121

Query: 122 LLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
           LLP +    + +++ ++LR A+VVPE+K VDRMLKEFR+Q  HMAIVIDEFG +SG++TI
Sbjct: 122 LLPLILKKNQPYNIGQILRPAMVVPENKGVDRMLKEFRAQHCHMAIVIDEFGSMSGIITI 181

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGG 241
           EDILELIVG IEDEYD ++D +  Q++  T+ + AL  +E+FN  F T+F +EE+DTIGG
Sbjct: 182 EDILELIVGNIEDEYDNKNDCNIYQVNHRTFLINALTPVEEFNIKFNTNFYNEEIDTIGG 241

Query: 242 LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            VMQ FGHLPARGE+IDI GY FK+ + D+ RIIQ+ V+IP + 
Sbjct: 242 FVMQTFGHLPARGESIDISGYIFKITVTDNHRIIQLLVQIPKNE 285


>UniRef50_D1B5K7 Putative uncharacterized protein n=1 Tax=Thermanaerovibrio
           acidaminovorans DSM 6589 RepID=D1B5K7_THEAS
          Length = 426

 Score =  309 bits (792), Expect = 9e-83,   Method: Composition-based stats.
 Identities = 86/253 (33%), Positives = 143/253 (56%), Gaps = 2/253 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
             R+E+  ++++   +  ++E+ R M+ G++   + RV +IM+PR+ ++ +    T+ + 
Sbjct: 168 VTREEIDHMVKEGSASGALEEEERKMIHGIISFEETRVSEIMVPRTDVVAVVAGSTVRDA 227

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           + + ++S HSR P+   D DH+ GIL  KDLL  +        ++   R  + VPE+ R+
Sbjct: 228 VRIFMDSGHSRMPIYEGDMDHVVGILYVKDLLRNLTQGDMDRPVEDCKRDCLFVPETMRI 287

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
             +    +  R HMA+V+DE+GG +GLVT+ED+LE IVGEI+DEYDEE  I   Q     
Sbjct: 288 GELFDRMKKARVHMAVVVDEYGGTAGLVTLEDLLEEIVGEIQDEYDEE--IPPIQEEGGV 345

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           + V+    +ED +EA G  F  E+VDT+ G V+   G  P  G+ I  D +  +V     
Sbjct: 346 FVVQGHVHLEDLSEALGHQFQAEDVDTVAGFVLSILGAFPEEGQGILYDDWSIEVTKVQG 405

Query: 272 RRIIQVHVKIPDD 284
            RI++V  +  +D
Sbjct: 406 HRIMEVRFRRLED 418


>UniRef50_D1Y8K6 CBS/transporter domain protein n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y8K6_9BACT
          Length = 421

 Score =  308 bits (791), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 90/250 (36%), Positives = 155/250 (62%), Gaps = 1/250 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
             ++E+  +++    +  I+E  R M++GV+   + RV +IMIPR++M  ++  +T+D+ 
Sbjct: 166 VTKEEIGQVVKIGEASGAIEESERQMIDGVISFDEIRVSEIMIPRTRMHMIESERTVDDA 225

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           L  I +   SR PV ++  D IEGI++ KDLL  +    +   + K +R  + VPE+  V
Sbjct: 226 LQFIEKMGDSRVPVFTDTPDRIEGIVLVKDLLTALMKGQKNAPVTKFMRTPLFVPETMYV 285

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
            ++ +  ++ R HMA+V+DE+GG +GL+T+ED+LE IVGEI+DEYD+E+      LS  T
Sbjct: 286 PKLFRIMQNVRMHMAVVVDEYGGTAGLITLEDLLEEIVGEIQDEYDKEEQ-TVTPLSDGT 344

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           +  +A   +E+ N+   +HF  ++VDT+GG ++  FG+ P  G+T+  DG+ F++A  D 
Sbjct: 345 YRAKASIPLEELNDVLNSHFVCDDVDTLGGFLLDRFGNFPHEGDTLASDGWLFEIASMDG 404

Query: 272 RRIIQVHVKI 281
            RI  V ++ 
Sbjct: 405 HRINDVMIRR 414


>UniRef50_Q74EV6 CBS domain protein n=9 Tax=Desulfuromonadales RepID=Q74EV6_GEOSL
          Length = 444

 Score =  308 bits (791), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 90/283 (31%), Positives = 153/283 (54%), Gaps = 4/283 (1%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           TISNK     + +          R+E+  ++ +  +  +     ++ +  + D     VR
Sbjct: 158 TISNKAVLAMMGIKAEGSQAFVTREEVQHIVAEGHEAGVFSATEQEYIRNIFDFTHTCVR 217

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           ++M+PR++M+ L   +   E +  ++++ +SR+PV  E  +++ G +  KDLL    +D 
Sbjct: 218 EVMVPRTRMVALDLARPRMELVREVLDNMYSRYPVYRESIENVVGFIHGKDLLGRTVTDP 277

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           E F+M+ ++R    VPE K+V+ +LKE +  R HMA+V+DE+GG+SGLVT ED+LE +VG
Sbjct: 278 E-FAMESIVRPPFYVPEGKKVNELLKEMQRLRIHMALVVDEYGGISGLVTTEDLLEELVG 336

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGH 249
           EIEDE+D  +    ++L   +  V AL SI D  +       ++   DT+ GL++   G 
Sbjct: 337 EIEDEHDIGEPGTVQRLPDGSLLVDALMSIGDLADLLKIKLEEDVPYDTLAGLILDQLGR 396

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            P RGET++ D +           I  V V+I ++ P    DE
Sbjct: 397 FPERGETVEWDRFSLICEEVKQTAI--VKVRIVENLPPQAGDE 437


>UniRef50_A1WVF4 CBS domain containing protein n=2 Tax=Ectothiorhodospiraceae
           RepID=A1WVF4_HALHL
          Length = 291

 Score =  308 bits (790), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 121/280 (43%), Positives = 179/280 (63%), Gaps = 1/280 (0%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M D  ++SS+       +   L   +   EP++RDEL+  +R S    L+D D   M+EG
Sbjct: 1   MPDGEANSSNGAGESVSWRDRLRRLVTQVEPRSRDELVDHLRRSQSVGLLDADALSMIEG 60

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V+ +++ + RDIMIPRSQ+ T+ R+    + L  I+ + +SRFPV  E KD + GIL+AK
Sbjct: 61  VLHVSELQARDIMIPRSQVTTVARDTAPHDLLPTIVRTGYSRFPVTGESKDDVIGILLAK 120

Query: 121 DLLP-FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLL  F       F + +VLR  + +PESKR+D +LK+FR  R HM++V+DE+GG++G+V
Sbjct: 121 DLLRLFYEEGHNGFRLREVLRPVLFIPESKRLDALLKQFRESRNHMSVVVDEYGGLAGIV 180

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED++E IVGEI+DE+D ++D         +W V+A+  IE FNEA      ++++DT+
Sbjct: 181 TIEDVIEQIVGEIDDEHDFDEDAPILARDDGSWIVKAVTPIEAFNEALSAGLKEDDLDTV 240

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           GGLV Q FGH+P RGE I   G++F+V  AD RRI  + V
Sbjct: 241 GGLVAQRFGHVPCRGERIVFAGFEFRVLRADQRRIHLLRV 280


>UniRef50_Q5ZVK1 Mg2+ and Co2+ transporter CorC n=6 Tax=Legionella
           RepID=Q5ZVK1_LEGPH
          Length = 296

 Score =  307 bits (788), Expect = 3e-82,   Method: Composition-based stats.
 Identities = 122/269 (45%), Positives = 179/269 (66%), Gaps = 1/269 (0%)

Query: 10  DTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           + + +   +FS L  Q   GEP+N++EL++L+RD+    LI+ +T  M+EG +  +  RV
Sbjct: 13  NKLEDGGSWFSRL-KQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRV 71

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           RDIM+P++QM+ + ++      + ++ ++ HSRFPV  E+ D + GIL AKDLL +   +
Sbjct: 72  RDIMLPKNQMVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPEN 131

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            E+F +  + RQ   VPES+R+D +L EFRS R HMAIV+DE+G VSG VTIEDI+E I+
Sbjct: 132 MESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVVDEYGEVSGFVTIEDIIEQII 191

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G+IEDE+D ++D   +    H + ++A   IE+FNE     FSDE  DTIGG+V+  FG+
Sbjct: 192 GDIEDEFDIDEDAYIKTHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGIVLNKFGY 251

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVH 278
           LP RGE I ID ++FKV  ADSRRI  + 
Sbjct: 252 LPQRGEVIIIDDFEFKVLNADSRRIKLLE 280


>UniRef50_Q47RN3 CBS domain protein n=1 Tax=Thermobifida fusca YX RepID=Q47RN3_THEFY
          Length = 439

 Score =  306 bits (786), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 91/253 (35%), Positives = 139/253 (54%), Gaps = 9/253 (3%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G     +EL  L+  + +  +ID + R M+  V  + D  VR++MIPR  ++ L+ N ++
Sbjct: 165 GPFATEEELRHLVDLAERGHVIDPEERQMIHSVFQLDDTTVREVMIPRPDIVFLEGNVSI 224

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR--------SDAEAFSMDKVLR 140
           +E L+  + S +SR PVI E  D + GI+  KDL+  +         + A   ++  V+R
Sbjct: 225 EEALEKALSSGYSRIPVIGESLDDVIGIVYLKDLVARLYDAWRANGGAPAPGRTIRDVMR 284

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
           +   VP+SK VD +L+E + QR H+A+VIDE+GG +G+VTIEDI+E IVGEI DEYD+E 
Sbjct: 285 EPTYVPDSKPVDELLREMQQQRIHLAVVIDEYGGTAGIVTIEDIVEEIVGEITDEYDDEV 344

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
                 L  +   V A   + +  E FG      +VDT+GGL+  A G +P  G   +  
Sbjct: 345 PP-IEWLDDNRARVTARLPLGELAELFGVEIDAPDVDTVGGLLAYALGRVPVPGSQAEYA 403

Query: 261 GYQFKVAMADSRR 273
           G +        RR
Sbjct: 404 GLRLVAEDPARRR 416


>UniRef50_D2LWG5 Putative uncharacterized protein n=3 Tax=Bacillus
           RepID=D2LWG5_BACS4
          Length = 415

 Score =  306 bits (786), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 91/264 (34%), Positives = 139/264 (52%), Gaps = 1/264 (0%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           F S L+ +         +EL  LI  S +  +IDE  R+++   +D  D  V +I+ PR 
Sbjct: 152 FVSKLIKKEKTAPSVTEEELKELISISEEEGVIDESERELVHRSLDFNDIIVAEIVTPRM 211

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            ++ +  N T+DE  +  I+  +SR PV   + D+I GIL  +D L           + K
Sbjct: 212 DIVAIDVNNTVDEIKNTFIKERYSRIPVYEGNIDNIIGILSERDFLKAYIQLEYDVDIRK 271

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
           +LR  V V ES R+  +L + +  + HMAIVIDE+GG  GL+T+EDILE IVGEI DE+D
Sbjct: 272 LLRDPVFVFESMRIHTLLPQLQKNKGHMAIVIDEYGGTEGLITLEDILEEIVGEIWDEHD 331

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
           E+ ++  +Q+   T  V A   ++DF         D    TIGG + + F  +P+  E +
Sbjct: 332 EDINL-LKQVDPSTLIVHADCPLDDFVRKTKIELPDTPYHTIGGWLSEVFQRIPSVNEEV 390

Query: 258 DIDGYQFKVAMADSRRIIQVHVKI 281
             +    K+  AD RRI  + V +
Sbjct: 391 QYEHISLKIIDADERRIRAIEVSL 414


>UniRef50_C1TQS8 CBS domain-containing protein n=2 Tax=Synergistaceae
           RepID=C1TQS8_9BACT
          Length = 425

 Score =  306 bits (785), Expect = 7e-82,   Method: Composition-based stats.
 Identities = 78/254 (30%), Positives = 140/254 (55%), Gaps = 1/254 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
             R+E+  ++     +  ++E  R M+ G++   D +V ++M+PR  M  +  + T++E 
Sbjct: 166 VTREEIEQVVTIGEASGALEESERRMIHGIISFEDTKVSEVMVPRIDMDVVDSDITIEEL 225

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           +  + E  HSR P+  +  D I GIL  KDL+  + S      +  + R A+ VPE+ +V
Sbjct: 226 IPHLEEHGHSRIPIYEDSLDDIIGILYVKDLIGLLYSGKTEVKLASLKRDALFVPETMKV 285

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
             +    +S+R HMA+V+DE+GG +G++T+ED+LE IVGEI+DEYD E      ++    
Sbjct: 286 PDLFNIMKSRRIHMAVVVDEYGGTAGIITLEDLLEEIVGEIQDEYDHELPA-IEEVEEGV 344

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           + V+    +ED ++  G  F  E+V+++GGL+    G  P  G ++    ++F V     
Sbjct: 345 YQVQGNMDLEDLSDFLGYPFESEDVESVGGLITDLSGDFPGTGSSVTYGPWEFTVLSLAD 404

Query: 272 RRIIQVHVKIPDDS 285
            R+++V ++  D  
Sbjct: 405 HRVMEVELRKIDSE 418


>UniRef50_Q2JP27 Putative transporter, HlyC/CorC (HCC) family n=2 Tax=Synechococcus
           RepID=Q2JP27_SYNJB
          Length = 480

 Score =  305 bits (783), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 77/264 (29%), Positives = 136/264 (51%), Gaps = 4/264 (1%)

Query: 31  PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDE 90
               +EL  LI  S ++  I+ + R++L  + +  +    ++MIPR+ +  +    T+ E
Sbjct: 204 TMTVEELQLLIASSVESGNIEAEERELLSNIFEFGETVASEVMIPRTSIDAVPETATVQE 263

Query: 91  CLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF--SMDKVLRQAVVVPES 148
            L  + ES HSR+PV  E  D I G++  K+L+  +   +      +   +R+A   PE+
Sbjct: 264 VLAEVAESGHSRYPVYGESLDDIRGLIHVKELIGQLAKGSIDLHSPITPFIREAHFEPEN 323

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE-DDIDFRQL 207
           K +  +L E R   + M +V+DEFGG +GL+TI+D++E IVG++ D  D    + D ++L
Sbjct: 324 KPIAELLPEMRQHHWPMVVVVDEFGGTAGLITIQDLVEEIVGKLSDGPDPNTKEPDIQEL 383

Query: 208 SRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
             +T  ++A   IE+ NE  G +    E+  T+GG ++     +P  GE       +F+V
Sbjct: 384 DENTLLIQAQLDIEEINERCGLNLPLHEDYQTLGGFLIYHMQKIPRAGEKFTYQEMEFQV 443

Query: 267 AMADSRRIIQVHVKIPDDSPQPKL 290
              +  R+ +V V     +P   L
Sbjct: 444 VRMEGPRVDRVKVARRPGTPANSL 467


>UniRef50_C5VQE4 CBS domain integral membrane protein n=9 Tax=Clostridiales
           RepID=C5VQE4_CLOBO
          Length = 429

 Score =  305 bits (783), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 83/277 (29%), Positives = 151/277 (54%), Gaps = 10/277 (3%)

Query: 12  ISNKKGFFSLLLSQLFH--------GEPK-NRDELLALIRDSGQNDLIDEDTRDMLEGVM 62
           ++     F+LL +++          G+P    +EL  ++  S +  +++ + R M+  V 
Sbjct: 138 LTPLTSIFTLLTNKIVRIFGGRADMGKPHITEEELKTIVDVSHEEGVLEVEERKMIYNVF 197

Query: 63  DIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL 122
           +  D +V+D+M+PR++MI++  + T DE ++++ +   SR PV  +  D+I G+L  K L
Sbjct: 198 EFGDSQVKDVMVPRTEMISIDVDSTYDEVIEILKKEQFSRMPVYKDSTDNIIGVLHIKRL 257

Query: 123 LPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIE 182
           + F  +  + F + K + +     E K    +  E R  R  M IV+DE+GG +G+VT+E
Sbjct: 258 V-FFDNSKDKFDIYKYMIKPYFTYEYKPTTELFDEMRKNRVAMTIVLDEYGGTAGMVTME 316

Query: 183 DILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGL 242
           D++E IVG+IEDEYD E + + + +    + V+    I++ NE   T    E+ D+IGG 
Sbjct: 317 DLVEEIVGDIEDEYDNEQNDEIKLIKEDEYIVKGSTKIDEVNEMLKTSIESEDFDSIGGF 376

Query: 243 VMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           V+   G  P +GE I+    +F +   D+ RI ++ +
Sbjct: 377 VIGEIGRFPKKGEVIEFGNIKFIIEEIDNNRIKKLKI 413


>UniRef50_B9KAC3 Hemolysin-related protein n=1 Tax=Thermotoga neapolitana DSM 4359
           RepID=B9KAC3_THENN
          Length = 466

 Score =  305 bits (783), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 73/256 (28%), Positives = 145/256 (56%), Gaps = 4/256 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              ++++++++  G+  +I+++   +++   ++    V++IM PR  ++ ++ NQT+ + 
Sbjct: 189 ITEEDIVSIVQVGGEMGVIEQEEERIVKRAFEMKQIAVKEIMTPRVDIVAIEENQTVRDL 248

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS----DAEAFSMDKVLRQAVVVPE 147
           +++I +  +SR PV  E  D+I G+  AKD+L  +      + +   +  ++R A+ VPE
Sbjct: 249 IELIEDEGYSRIPVYRETIDNIVGVCYAKDVLSILAEKDCEEVKNMKVKDIMRDALYVPE 308

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  +D +LK  +S++ H+AIV+DE+GG +G+VT+EDI+E + G+I DEYD ++    +++
Sbjct: 309 TMNIDELLKILKSKKIHIAIVVDEYGGTAGIVTLEDIIEELFGDIMDEYDYDEVSGIKKI 368

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
              T+ V     I D        F   E +TI G +++ F  +P  GE   I    FKV 
Sbjct: 369 GEKTYIVDGSTPINDLEIELRIQFPQTEYETIAGYLLEHFKRIPNVGEEAVIGNLYFKVL 428

Query: 268 MADSRRIIQVHVKIPD 283
                RI ++ +K+ +
Sbjct: 429 AVGKNRIEKIMIKVLE 444


>UniRef50_B8G2E5 Putative uncharacterized protein n=3 Tax=Clostridiales
           RepID=B8G2E5_DESHD
          Length = 437

 Score =  305 bits (782), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 78/256 (30%), Positives = 142/256 (55%), Gaps = 2/256 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +EL  L+  S ++ ++D+    +L+ V + +D+ V ++M+PR  M+ L    +++E 
Sbjct: 171 HTEEELRMLVDASQRHGILDKMEGKLLDNVFEFSDRVVSEVMVPRQDMMCLYIQDSMEEV 230

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           L+ +  S H+R+P+  +DKD++ G++  +DLL    S++   ++ ++ R  ++VPE   +
Sbjct: 231 LETVKTSGHTRYPLCDDDKDNVIGLVHMRDLLSL--SESSVKNIGELKRDILIVPEGMPI 288

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
             ++++ R QR H+A+V+DEFGG +G+VTIED++E +VGEI DE++  +  +  +     
Sbjct: 289 SHLVQKMRVQRTHLAVVVDEFGGTAGMVTIEDLIEELVGEIYDEFESAEQAEIIKSGESE 348

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           + +     ++D +E     F DE V TIGG V    G  P +G+ ID   Y F V     
Sbjct: 349 YLINGRVLLDDLSELLAVEFEDETVSTIGGFVFNRLGRKPVKGDRIDFMDYTFTVMEVVG 408

Query: 272 RRIIQVHVKIPDDSPQ 287
            RI +V          
Sbjct: 409 FRITRVKASRRPAPDS 424


>UniRef50_C7LZP2 CBS domain containing protein n=1 Tax=Acidimicrobium ferrooxidans
           DSM 10331 RepID=C7LZP2_ACIFD
          Length = 420

 Score =  304 bits (781), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 91/265 (34%), Positives = 148/265 (55%), Gaps = 1/265 (0%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
              +LL      G   +  ELLA+   + Q D+I+ D R+++  V+   D   R++M+PR
Sbjct: 149 SLSALLTPWRAPGATVSEAELLAMADAAEQGDVIETDERELIHSVISFGDTIAREVMVPR 208

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
             ++ +    T+   ++V+IE   SR PV     D++ GI++AKDLL    +      + 
Sbjct: 209 PDVVAVPAETTVAGAIEVVIEVGRSRLPVYESSLDNVLGIVLAKDLLALEHTGLRDVPVG 268

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
           + +R    VPE+K V  +LKE R  ++H+A+V+DE+G  +G+VT+ED++E +VGEI DE+
Sbjct: 269 QHMRPIHFVPETKPVADLLKEMRDGKFHLAVVVDEYGSTAGIVTLEDLIEELVGEIHDEF 328

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           D   +    +L    W VR   SI+D +E  G    + E D++GGL+M   GHLP  GE 
Sbjct: 329 DAGGE-GVVELGEGRWEVRGSVSIDDLSERIGEELPEGEWDSVGGLIMGLLGHLPRVGEE 387

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKI 281
           +D+DG + +V      R+  V V+ 
Sbjct: 388 VDVDGVRLQVRQVARHRVASVLVER 412


>UniRef50_C6L9Q9 CBS domain protein n=6 Tax=Clostridiales RepID=C6L9Q9_9FIRM
          Length = 424

 Score =  304 bits (780), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 89/278 (32%), Positives = 151/278 (54%), Gaps = 10/278 (3%)

Query: 19  FSLLLSQLFHGEP------KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
            S LL +L   +P         +EL   +  S ++ +I+++ + M+  V D  D + +DI
Sbjct: 148 LSNLLIRLLGVDPNAKGDVMTENELRTYVDVSHEDGVIEQEEKQMIYNVFDFGDTQAKDI 207

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           MIPR +M+++  N +  E L V  E   +R PV  E  D++ G+L  KD + F   D  +
Sbjct: 208 MIPRVEMVSIDVNASYQEVLKVFREEKFTRLPVYEESTDNVIGVLNIKDFIFF---DENS 264

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
           F M  ++R+     E K    ++ + R    +  IV+DE+G  +GL+T+ED+LE IVGEI
Sbjct: 265 FDMRSMMREPNFTYEYKSTSELMDQMRQSSVNFTIVLDEYGATAGLITLEDLLEEIVGEI 324

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DEYD++++   +++S   + +     ++D N+A       E+ D+IGGL++    HLPA
Sbjct: 325 RDEYDKDEEELIKKISDREYILPGFMKLDDVNDALDLLLHSEDYDSIGGLIIGELDHLPA 384

Query: 253 RGETIDI-DGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            GE++   DG +  V   D  RI QVH+ +P+   + +
Sbjct: 385 VGESVTTPDGIRLVVEAVDKNRINQVHLYLPEKKEETE 422


>UniRef50_B5JWG7 CBS domain containing protein n=3 Tax=Gammaproteobacteria
           RepID=B5JWG7_9GAMM
          Length = 298

 Score =  304 bits (779), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 133/294 (45%), Positives = 193/294 (65%), Gaps = 3/294 (1%)

Query: 1   MSDDNSHSSD--TISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDML 58
           M D+ S SS     +++  +   L       +P+N D++L ++RD+ +  L D     M+
Sbjct: 1   MKDEPSSSSRQGRSASQPNWLEKLGQAFGGNDPQNLDQILEVLRDAQERGLFDLHALAMV 60

Query: 59  EGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILM 118
           EGV ++ + RVRDIMIPRS M  L++     + L+++ ES HSRFPVI+ D+D + G+L+
Sbjct: 61  EGVFEVTEMRVRDIMIPRSHMTVLEQGADFGDVLNILTESGHSRFPVIAGDRDELVGVLL 120

Query: 119 AKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           AKD+L +     E F++D +LRQ V++PESKR+  +L EFRS R H+A+V+DE+GGVSGL
Sbjct: 121 AKDVLKY-AGRPEEFALDDILRQVVIIPESKRLITLLNEFRSSRNHLAMVVDEYGGVSGL 179

Query: 179 VTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDT 238
           VTIED+LE+IVGEI+DE+D E+D   R   +  +TV AL  IE+FN  F T  SDE+ DT
Sbjct: 180 VTIEDVLEVIVGEIDDEHDSEEDHYIRPHRKGHYTVHALTEIEEFNAFFKTTLSDEDADT 239

Query: 239 IGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           IGG VM+  GH+P RGE ++ +G  F V  ADSRRI ++ V   +   +P + E
Sbjct: 240 IGGYVMRLLGHVPKRGEQVESEGILFTVLGADSRRIYRLKVTTEESLDEPTMAE 293


>UniRef50_A9KQ60 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A9KQ60_CLOPH
          Length = 429

 Score =  303 bits (776), Expect = 7e-81,   Method: Composition-based stats.
 Identities = 81/267 (30%), Positives = 138/267 (51%), Gaps = 1/267 (0%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
            F L +           +EL  ++  S +  +I+ + R M+  V+D  D   +D+M+PR 
Sbjct: 152 LFILRVDPNKKYVTMTENELRTIVDVSHEEGVIESEERKMITNVVDFGDSLAKDVMVPRI 211

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            M     + +  + ++V  E  +SR PV  E++D I GI+  KD+  F R D   F++  
Sbjct: 212 NMAFASVDMSYSQLIEVFREEQYSRMPVYDENRDDIVGIINLKDVF-FFRGDYNEFNIRD 270

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
            +R+     E K+   +L E + +   M IV+DE+G  +GL+T+ED+LE IVGEI DEYD
Sbjct: 271 YMREPYYTYEYKKTSELLSEMKRESLPMVIVLDEYGATAGLITMEDLLEEIVGEIRDEYD 330

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
            +++    +L  + +     A +++ NE  G     E+ D+I G ++    HLP + E I
Sbjct: 331 YDEEDVITKLGENEYLADGSAKLDEINEFIGLSLDSEDYDSIAGHIIHLLDHLPEQDEQI 390

Query: 258 DIDGYQFKVAMADSRRIIQVHVKIPDD 284
             +   + V   +  RI +VH+KI  +
Sbjct: 391 TENNITYTVTKVEKNRIDKVHIKIEPE 417


>UniRef50_C3WJU6 Magnesium and cobalt efflux protein corC n=15 Tax=Fusobacterium
           RepID=C3WJU6_9FUSO
          Length = 427

 Score =  302 bits (774), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 88/271 (32%), Positives = 158/271 (58%), Gaps = 7/271 (2%)

Query: 18  FFSLLLSQLFHGE------PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           F S  + ++              +++++ +       +I+ED ++M+  ++ + +   ++
Sbjct: 148 FISRFVGRILGVNMESPQLLITEEDIISYVNVGNAEGIIEEDEKEMIHSIVTLGETSAKE 207

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M PR+ M +L+  +T++E  D I E+  SR PV  E  D+I GIL  KDL+  ++++  
Sbjct: 208 VMTPRTSMFSLEGEKTINEIWDEITENGFSRIPVYEETIDNIIGILYVKDLMEHVKNNEL 267

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              + + +R A  VPE+K +  +LKEFR+ + H+A+V+DE+GGV GLVTIED++E IVGE
Sbjct: 268 DIPIKQFVRSAYFVPETKSIIEILKEFRTLKVHIAMVLDEYGGVVGLVTIEDLIEEIVGE 327

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHL 250
           I DEYD+E+D  F++++ + + V A+  IE  N+         E+ +++GGL++   G +
Sbjct: 328 IRDEYDDEEDSFFKKIADNEYEVDAMTDIETINKELELELPISEDYESLGGLIVTTTGKI 387

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
              G+ + ID    KV   D  R+ +V +KI
Sbjct: 388 CEVGDEVQIDNIYLKVLEVDKMRVSKVFIKI 418


>UniRef50_C1ZDU6 CBS domain-containing protein n=1 Tax=Planctomyces limnophilus DSM
           3776 RepID=C1ZDU6_PLALI
          Length = 439

 Score =  301 bits (772), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 89/289 (30%), Positives = 158/289 (54%), Gaps = 12/289 (4%)

Query: 14  NKKGFFSLLLSQLF-HGEPKN------RDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           +   +   +  +L   GEP+        DE+  ++ +  +   +++  R M+  VM++ D
Sbjct: 147 SLAKWLDRMAHRLVGRGEPEEDDASVLSDEIRTVVDEGQREGYLEQGARVMIHRVMELQD 206

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
           + V  IM PR+ M ++    +L+E    +I S HSR PV+++  D I G+L +KDLL  +
Sbjct: 207 EDVGGIMTPRTDMFSIPLGASLEEARQKLISSGHSRVPVVADSPDEIVGLLYSKDLLKAL 266

Query: 127 R---SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIED 183
               +      + ++LR+   +PE+  +  +L+  + + + +AIV+DE+GGV+GLVT+ED
Sbjct: 267 DPACARDSLPKLSEILREPKYIPETTGIAALLEMMQREHFQLAIVLDEYGGVAGLVTMED 326

Query: 184 ILELIVGEIEDEYDE-EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGG 241
           ILE IVGEI DEYD  E +   ++++ +   + A   I+D NE F     ++ E DTIGG
Sbjct: 327 ILEEIVGEIADEYDTLEGESPVKKIAPNIVEIDARMHIDDLNEQFLYGLPEDGEFDTIGG 386

Query: 242 LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
            V    G +P+ GE  D +  +  +  AD R+I+++ ++ P +      
Sbjct: 387 FVFSQLGRMPSTGEIFDWNNLKMTIIEADKRKILRLRIEQPSEVTTESS 435


>UniRef50_Q3SVM7 Mg2+ and Co2+ transporter CorB family n=15 Tax=Alphaproteobacteria
           RepID=Q3SVM7_NITWN
          Length = 449

 Score =  301 bits (771), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 82/283 (28%), Positives = 145/283 (51%), Gaps = 9/283 (3%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +++    +L + ++   +     E+  LI +S ++  I+    + ++ V    D  V D+
Sbjct: 160 ASRAILRALRVKEVSQHDVLTGAEIEGLIGESAEHGGIESGEAEYIQNVFRFGDLAVSDV 219

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR---SD 129
           M+ R+ M+T+  +   ++ +  ++ S ++R P+  +  ++I G+L AKDLL  +     D
Sbjct: 220 MVHRTAMVTINADLPPEDLVREVLASEYTRIPLWRDKPENIVGVLHAKDLLRAIHASEGD 279

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
               +++ +      VPE + V   LK FR ++ H A+V+DE+G V G+VT+ED+LE IV
Sbjct: 280 IARINVNAIALPPWFVPEMRPVSDQLKAFRRRKTHFALVVDEYGEVEGMVTLEDVLEEIV 339

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G+I DE+D       RQ +  +  V     I D N A   H  DEE  TI GLV+     
Sbjct: 340 GDISDEHDVV-VAGVRQQADGSVVVDGSVPIRDLNRAMDWHLPDEEATTIAGLVIHEARS 398

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           +P RG+     G++F+V   +  RI  + ++     P P+  E
Sbjct: 399 IPERGQNFTFYGFRFRVLRRERNRITALRIQ-----PVPRGGE 436


>UniRef50_C6J8N4 Putative uncharacterized protein n=1 Tax=Ruminococcus sp.
           5_1_39BFAA RepID=C6J8N4_9FIRM
          Length = 459

 Score =  301 bits (771), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 83/281 (29%), Positives = 151/281 (53%), Gaps = 15/281 (5%)

Query: 18  FFSLLLSQLFHGE------PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           + + L +  F  E          +E+++++ ++ +  +I E+  +M++ ++   +    D
Sbjct: 177 WIARLAAVPFGVEINRTEKSVTEEEIISIVDEAHEQGVIQENEAEMIQNIISFNETEAHD 236

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM  R  ++       L   +D ++E  +SR+PV  E+ D+I+GI+  KD L FM  +  
Sbjct: 237 IMTHRKNVVAFDEEILLKNMIDTMLEEGNSRYPVYEENIDNIKGIVHYKDALKFMTQNPW 296

Query: 132 A-----FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
           A       +  ++RQA ++PE++ +  +    ++++ HMAIV+DE+G  +G+VT+EDILE
Sbjct: 297 AKFKPLKELPGIIRQASLIPETRGIGDLFHTMQARKIHMAIVVDEYGQTAGIVTMEDILE 356

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            IVG+I DEYD ED+I  R    ++  +  LA +ED  E     F D E +T+ G +   
Sbjct: 357 EIVGDILDEYD-EDEITIRAQKDNSLIIDGLAYLEDVEEELDADFGDTEFETLNGYLTNI 415

Query: 247 FGHLPA---RGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
            GH+PA      +I   GY F +    ++ I +V V+  ++
Sbjct: 416 LGHIPADKDVNTSIKAIGYCFTILSIGNKTIGKVKVERDNN 456


>UniRef50_A9BGT5 Putative uncharacterized protein n=1 Tax=Petrotoga mobilis SJ95
           RepID=A9BGT5_PETMO
          Length = 448

 Score =  300 bits (769), Expect = 4e-80,   Method: Composition-based stats.
 Identities = 73/272 (26%), Positives = 144/272 (52%), Gaps = 13/272 (4%)

Query: 23  LSQLFHGEPKN-------RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
             +LF GE           DE+++ +    +  +I++  + +++  +++ D  V++IM P
Sbjct: 159 FIKLFGGETITNAPPLITEDEIISYLDIGHEEGVIEKSEKYLMQRSLEMKDTSVKEIMTP 218

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  ++ ++  +T++E + +I E  +SR PV  E  D++ GI+ AKD+   +    +   +
Sbjct: 219 RVDILAIEDTKTMEELIKIINEEGYSRIPVFKETLDNVIGIVYAKDIFKKLDEVKDFTKL 278

Query: 136 D-----KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
                 +++ +   VP + ++  + + F +   HMAIV+DE+GG +GLVT+EDI+E + G
Sbjct: 279 QKLRVVEIMHKPFFVPITMKIRDVFRLFLNNHTHMAIVVDEYGGTAGLVTLEDIIEEMTG 338

Query: 191 EIEDEYDE-EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           EI DEYD+  D+ +  +++ +   V     I D        F + E +TIGG +++ F  
Sbjct: 339 EIFDEYDDYSDETNIIRVAENVILVDGTTPINDVERELDIEFPETEFETIGGFLLERFKR 398

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
            P  GE   I+  +F++      +I +V + +
Sbjct: 399 FPKPGEIYYIENIEFEIVSVTINKIDKVKITV 430


>UniRef50_B8KMV1 Magnesium and cobalt efflux protein CorC n=3 Tax=unclassified
           Gammaproteobacteria RepID=B8KMV1_9GAMM
          Length = 282

 Score =  299 bits (766), Expect = 9e-80,   Method: Composition-based stats.
 Identities = 144/283 (50%), Positives = 199/283 (70%), Gaps = 5/283 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MSDD + + +   +  G     ++Q F  EP+ R++L  +++ + +ND+I+ED+  +++G
Sbjct: 1   MSDDRNGNGNEEKSLLG----RIAQAFSSEPRTREDLQQILQLAMENDIIEEDSLSIIDG 56

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            M ++  + RDIM+PR QM+ +K   TL+E L  I ES HSR+PVI E  D I GIL+ K
Sbjct: 57  AMQVSGMQARDIMVPRPQMVVIKSESTLEEVLQHISESKHSRYPVIGESPDDILGILLVK 116

Query: 121 DLLPFMRS-DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLLP + S D E F + ++LRQ+VVVPESKR++ +L+EFR  R HMAIVIDE+GGV+GLV
Sbjct: 117 DLLPQILSEDRENFDIRQLLRQSVVVPESKRLNVLLREFRENRNHMAIVIDEYGGVAGLV 176

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVGEIEDE DEE+D   R++S   + VRAL  IEDFN+ F   FSD+E DTI
Sbjct: 177 TIEDVLEEIVGEIEDETDEEEDQFIRRISDDDFFVRALTPIEDFNDYFDVAFSDDEFDTI 236

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           GGLVM AFGH+P R E   I+G++FKV  AD R+I  + ++ P
Sbjct: 237 GGLVMHAFGHMPTRNEITHIEGFEFKVINADQRKIHSLRLRPP 279


>UniRef50_B7RC07 CBS domain integral membrane protein n=5 Tax=Thermotogaceae
           RepID=B7RC07_9THEM
          Length = 455

 Score =  299 bits (766), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 76/258 (29%), Positives = 147/258 (56%), Gaps = 4/258 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              ++++++++  G+  +I+E+   +++   ++    V++IM PR  ++ ++ NQT+ + 
Sbjct: 176 ITEEDIVSIVQVGGEMGVIEEEEERIIKRAFEMKQIAVKEIMTPRVDIVAIEENQTVKDL 235

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR----SDAEAFSMDKVLRQAVVVPE 147
           ++++ +  +SR PV  E  D+I GI  AKD+L  +      + +A  +  ++R+A+ VPE
Sbjct: 236 IELVEDEGYSRIPVYKETIDNIVGICYAKDVLSILAAKDCEEVKAMKVKDIMREALYVPE 295

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  +D +LK  ++++ H+AIV+DE+GG +G+VT+EDI+E + G I DEYD ++    R++
Sbjct: 296 TMNIDELLKILKAKKIHIAIVVDEYGGTAGIVTLEDIIEELFGNIMDEYDYDEISGIRKI 355

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
              T+ V     I D        F + E +TI G +++ F  +P  GE   I    FK+ 
Sbjct: 356 DERTFVVDGTTPINDIEMELRVQFPETEYETIAGYLLEHFKRIPNVGEEAVIGNLYFKIL 415

Query: 268 MADSRRIIQVHVKIPDDS 285
                RI +V +KI +  
Sbjct: 416 AVGKNRIEKVMIKILEGE 433


>UniRef50_A1AQM4 CBS domain containing protein n=9 Tax=Desulfuromonadales
           RepID=A1AQM4_PELPD
          Length = 296

 Score =  299 bits (766), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 84/276 (30%), Positives = 152/276 (55%), Gaps = 1/276 (0%)

Query: 9   SDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
            +  +   G F L    +   +     E+  LI+ S    +++E+  +M+  +  +    
Sbjct: 16  EEGSTITSGIFKLFERFVHGRKKMTAYEIQDLIKASEDEGVVNEEESEMIRSIFSLRSTV 75

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS 128
           VR++M+PR  M  +  + T+ E L+ I+   HSR PV     D++ G+L AKD+L +   
Sbjct: 76  VREVMVPRIDMACISVDATVREILETILACGHSRIPVFENSVDNVIGLLYAKDMLKYWGL 135

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
             +   +  ++R    +PE+K ++++L+EF+++  H+AIVIDE+GG SGL+TIED+LE I
Sbjct: 136 SEDLIRVRSIMRPPYFIPETKNLEQLLQEFKNKHVHLAIVIDEYGGTSGLITIEDLLEQI 195

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VG+I+DE+D E+ + F      + T  A   IE+  + F      ++ DT+GGL+    G
Sbjct: 196 VGDIQDEHDREEAL-FTTNDDGSLTADARLPIEELEQLFDMEIEHDKFDTVGGLIFHLTG 254

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
            + A G+T++ +     V  +D R+I +V +   ++
Sbjct: 255 KISAPGDTVENEQLVIAVLDSDERKIKRVCITRKNN 290


>UniRef50_B5YFP5 CBS domain protein n=1 Tax=Thermodesulfovibrio yellowstonii DSM
           11347 RepID=B5YFP5_THEYD
          Length = 432

 Score =  298 bits (765), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 88/262 (33%), Positives = 151/262 (57%), Gaps = 3/262 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           L         +++EL  LI +  +  + + D R ++      A+  V++IM+P  QM+T+
Sbjct: 169 LRAFSQRGFISQEELKLLIEEGEEKGIFEPDERQLIHSAFSFAEITVKEIMVPAPQMVTV 228

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQA 142
               +++E  ++I++   SR+P + +D + I GIL AKD    +  + +   + ++L+  
Sbjct: 229 SIYMSVNEIKEIIMDEKFSRYPALGKDLNDIRGILHAKDFYNALIKNPDLLDIKRLLKPP 288

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
           + VPE+ +++ +LKE + +R HMAIV+DE+G V+GLVT+EDILE +VGEI DEYD E  +
Sbjct: 289 MFVPETMKINILLKEMQKKRVHMAIVVDEYGVVTGLVTLEDILEELVGEIRDEYDIE--M 346

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDG 261
               L   +  + A  SI D  E +G    + EE DT+GG ++ +   +P  G+T+D+DG
Sbjct: 347 PVITLPDGSMIIDATISIRDLKEDYGIEIEESEEYDTLGGFILTSLQRIPHVGDTVDMDG 406

Query: 262 YQFKVAMADSRRIIQVHVKIPD 283
             FKV     +RI ++  +  D
Sbjct: 407 KIFKVIEMVGQRISKIKYEAID 428


>UniRef50_B8J2R3 CBS domain containing protein n=3 Tax=Desulfovibrio
           RepID=B8J2R3_DESDA
          Length = 371

 Score =  298 bits (764), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 99/279 (35%), Positives = 161/279 (57%), Gaps = 4/279 (1%)

Query: 10  DTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           D  S         LS+LF  +  +++ L   I ++     ++ D   ML G++   D +V
Sbjct: 2   DGGSEGHSTIWSRLSRLFGHD--DQESLEKAILEARAEGEVEPDEESMLLGILRFNDLQV 59

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR-S 128
           +D MIPR+ +  +  +  + E   +I+ S HSR PV  E +D+I GIL AKDLL  M   
Sbjct: 60  QDTMIPRTDIDCVPHDMPMAEVAAIIVRSGHSRIPVYKETRDNIVGILHAKDLLRSMLDG 119

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           + +  S+  ++R+   VPE+K +  +L+EFR+++ H+AI +DE+GG SGL+TIED+LE I
Sbjct: 120 EGKVSSLAGLIREPFFVPETKSIRTLLQEFRARKQHIAIALDEYGGTSGLITIEDVLEEI 179

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VG+IEDE+D   + D R +  + + +   A +ED  +  G     +EVDTIGG +    G
Sbjct: 180 VGDIEDEHDTPREEDIRPVGDNIYELTGRALLEDLED-MGVDLDSDEVDTIGGYLSMEAG 238

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           H+PA GE+  + G+ F V  AD + I+++ ++  D +  
Sbjct: 239 HVPAPGESFTLRGWTFTVLEADRKLILRLRMEPADSAAS 277


>UniRef50_Q72A49 CBS/transporter associated domain protein n=4 Tax=Desulfovibrio
           vulgaris RepID=Q72A49_DESVH
          Length = 464

 Score =  298 bits (764), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 74/255 (29%), Positives = 139/255 (54%), Gaps = 6/255 (2%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G     +++  ++ +  ++ ++ +  R M E VM + D+ V  IM  R+++  L      
Sbjct: 176 GPSVTDEDIRGMLAEGVRSGVVLDAERTMSERVMRLGDRSVTSIMTHRTRVAWLDSEAPQ 235

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
           ++ ++ +  S +SRFPV   D D++ G++ A++ L      A+  ++   +RQ V +PE+
Sbjct: 236 EDIIERLAASTYSRFPVCDGDLDNVLGVIKAREYLAACAEGAD-VTLKNFMRQPVFIPET 294

Query: 149 KRVDRMLKEFRSQ-RYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
            R   +L+ FR+    H A+V+ E+G V G+VT+ D+LE IVG+I    DE D+ +  + 
Sbjct: 295 ARALDLLEAFRTTPHVHFAMVVGEYGEVQGIVTLNDVLEAIVGDIPS-PDEADEPEAVRR 353

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDE---EVDTIGGLVMQAFGHLPARGETIDIDGYQF 264
           +  +W +  +  I+D  +  G    DE   + +T+ GL++Q  G LPA G+T+ +    F
Sbjct: 354 ADGSWLLDGMMHIDDMADVTGLRLPDEKHGDFETLAGLLLQHLGKLPAIGDTLRLGPLHF 413

Query: 265 KVAMADSRRIIQVHV 279
           ++   D RRI +V +
Sbjct: 414 EIVDMDGRRIDRVLL 428


>UniRef50_UPI0001C36BB6 hypothetical protein ChatD1_07246 n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C36BB6
          Length = 351

 Score =  298 bits (764), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 77/274 (28%), Positives = 149/274 (54%), Gaps = 12/274 (4%)

Query: 18  FFSLLLSQLFH-GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           F  L+   +    E    +++++++ +  +  +++    +M+  + ++ D+   DIM  R
Sbjct: 51  FLKLIGIDMMSDNENVTEEDIMSMVNEGHEQGVLEAREAEMITNIFELDDKDAGDIMTHR 110

Query: 77  SQMITLKRNQTLDECLDVIIESAH-SRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF-- 133
             ++ L  + TL E ++ I++  + SR+PV  +D D I GIL  KD L    + +     
Sbjct: 111 KNLVALDGSMTLREAVNFILKEGYNSRYPVYEKDIDDITGILHMKDALIAAENGSNGMVP 170

Query: 134 --SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +D +LR+A  +PE++ +D + KE +SQ+ HM IV+DE+G  +G+VT+EDILE IVG 
Sbjct: 171 ICEIDGLLREAHFIPETRNIDSLFKEMQSQKIHMVIVVDEYGQTAGIVTMEDILEEIVGS 230

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFG 248
           I DEYD +++    Q    ++ +  +A +++  +     F +++    DTI G ++    
Sbjct: 231 IMDEYDVDEEF-IAQAEDGSYIISGMAPLDEVAKTLDIEFEEDDYDSYDTINGFLISRLD 289

Query: 249 HLPARGE--TIDIDGYQFKVAMADSRRIIQVHVK 280
            +P  GE   ++  GY FK+   +++ I  + V+
Sbjct: 290 RIPQEGEQTEVEYQGYGFKILQVENKMIHTIRVQ 323


>UniRef50_Q1DCR5 CBS/transporter associated domain protein n=2 Tax=Cystobacterineae
           RepID=Q1DCR5_MYXXD
          Length = 455

 Score =  298 bits (764), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 82/237 (34%), Positives = 140/237 (59%), Gaps = 2/237 (0%)

Query: 45  GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFP 104
              + +D+    ++  + +++D+R RD+M+PR++++T+    T DE L ++ E  HSR P
Sbjct: 189 AAKNEVDKSAPQLIRSIFELSDKRCRDVMVPRTEVVTVDVTITPDELLRLLAEENHSRIP 248

Query: 105 VISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYH 164
           V  +D DH+ G+L A+D++P +    E   +  ++R A  VP  K +  +L++ + Q+ H
Sbjct: 249 VYRDDVDHVIGVLHARDIIPLL-QHPELIVLQDIIRPAHFVPWMKPIGDLLRDMQKQKIH 307

Query: 165 MAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN 224
           MAIV+DE+GG  G+VT+EDIL  IVG+I DE+ E ++    +L+  ++ V A   ++ F 
Sbjct: 308 MAIVVDEYGGFMGVVTLEDILREIVGDIGDEF-EVEEKQVEKLADGSFLVDAALEVDAFT 366

Query: 225 EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           + FG    + + DT+GG +    GHLP  GE     G+QF VA  +  RI +V +  
Sbjct: 367 QTFGFPLPEGDFDTLGGFLSSMAGHLPDVGERFAYSGWQFVVASKEGPRIDRVRMSR 423


>UniRef50_A6CBK3 Hemolysin protein n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CBK3_9PLAN
          Length = 436

 Score =  298 bits (764), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 90/254 (35%), Positives = 149/254 (58%), Gaps = 7/254 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+L+++ +  +  +++ +   M++ VM++ D+ V  IM  R  M  +  N TLDE L  
Sbjct: 171 EEILSVVEEGARGGILESEAGKMIQRVMELQDEDVGAIMTQRMDMEYISVNATLDEALLK 230

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD------AEAFSMDKVLRQAVVVPES 148
            I+  HSR PVI E  D I GIL A++LL     +       E  ++ K++     +PE+
Sbjct: 231 FIDVGHSRIPVIGESTDDIVGILYARELLKHFSKENQNSESPEELTIQKLMFSPFYIPET 290

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             +D +L+  + +  HMAIVIDE+GGV+GLVT+ED+LE IVG+I DE+DEE++    +  
Sbjct: 291 TGIDSLLETMQKEHVHMAIVIDEYGGVAGLVTMEDVLEEIVGDIVDEFDEEEEQMIFETG 350

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
           ++T  V A   I+D NE +  +  +  + DTIGG V+   G +P  GET+     + +V 
Sbjct: 351 QNTLEVDARVHIDDLNEQYNYNLPEGKDFDTIGGFVITQIGKVPQPGETLTWQQLRIEVL 410

Query: 268 MADSRRIIQVHVKI 281
            +D RRI ++ +++
Sbjct: 411 ESDERRINKLRIEL 424


>UniRef50_A9B0K1 Putative uncharacterized protein n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9B0K1_HERA2
          Length = 427

 Score =  298 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 85/254 (33%), Positives = 148/254 (58%), Gaps = 1/254 (0%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H      +EL  ++    +  +I+ + RDM+EG+ + +D  VR++M+PR  ++ L    +
Sbjct: 158 HPLIVTEEELKLMVNVGEEEGVIEAEERDMIEGIFEFSDTAVREVMVPRIDIVGLAATAS 217

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           ++E L++ I + HSR P+  E  DH+ G+L AKDL P +R       +  ++RQ+  VP+
Sbjct: 218 MEEALNLFISAGHSRLPIYDESIDHVLGVLYAKDLFPLLRDGLRDAPLRSLVRQSYFVPD 277

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           S +VD +++  +S++ HMAI++DE+G  +GLVTIED+LE IVGEI+DE+D E+    +Q+
Sbjct: 278 SIKVDDLMRALQSRKVHMAIIVDEYGSTAGLVTIEDLLEEIVGEIQDEFDSEEAP-IQQV 336

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
             H W      SI+  N+A      +++VD++GG V+   G +P  G+ I       +V 
Sbjct: 337 GPHEWLFDGRVSIDAVNDATELTLINDDVDSLGGFVLSMLGSMPKVGDVIQAGDTTIEVV 396

Query: 268 MADSRRIIQVHVKI 281
                R  ++ + +
Sbjct: 397 TIQGLRPQRLRLSL 410


>UniRef50_D1C4W4 Putative uncharacterized protein n=1 Tax=Sphaerobacter thermophilus
           DSM 20745 RepID=D1C4W4_SPHTD
          Length = 445

 Score =  298 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 88/276 (31%), Positives = 151/276 (54%), Gaps = 6/276 (2%)

Query: 18  FFSLLLSQLFHGEPK---NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           +        +  E       +EL  L+  S +   ++   ++M+  ++  AD     +M+
Sbjct: 168 WLLRPFGLRYQSESHLVYTVEELEMLVEASARGGQLETSEQEMIHRLLTFADLDAGQVMV 227

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAF 133
           PR++MI +  + TL E ++VI     SR+PV  +  D I GI+ +KDL P + +   + F
Sbjct: 228 PRTEMIAVPVDITLPELIEVIARERRSRYPVYDQTLDDIVGIVHSKDLFPILAAGKTDGF 287

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           S+ ++ R+A+ VP+S  +D++L   + +R H+AIVIDE+GG +GL+T+ED++E IVGE++
Sbjct: 288 SIREITREAMTVPDSLPIDQVLALMKQRRTHIAIVIDEYGGTAGLITMEDLVERIVGELQ 347

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DE++  +  +   L   +  +  L  IE+ NE FG    D   DTIGG V    G  P  
Sbjct: 348 DEFERPEQ-EVEVLPDGSVRINGLMLIEEVNERFGLDIHDPNFDTIGGYVFGQLGRKPEV 406

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           G+T+ +    F+V + D  RI ++ + I D  P  +
Sbjct: 407 GDTVQVGDVTFRVDVLDGLRIARLCL-IRDHVPSEE 441


>UniRef50_D2RIW5 CBS domain containing protein n=2 Tax=Acidaminococcus
           RepID=D2RIW5_ACIFE
          Length = 284

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 81/262 (30%), Positives = 146/262 (55%), Gaps = 2/262 (0%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   + D++  ++  S +   ID     +++ V D AD+  R++M+PR  M+ L  +  +
Sbjct: 21  GTSHSEDDIRKMVSASEKGGSIDPVESRLIDNVFDFADRVAREVMVPRQDMVCLFVDDPI 80

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
           +E + VI ES H+R+P+  ED+DHI G++  ++ +         F +  ++R+  VVPES
Sbjct: 81  EENMKVIRESGHTRYPLCEEDRDHILGMVHIREFMNADYKQP-GFDLRSIMREIDVVPES 139

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             + ++L+  + +   MA V DE+GG +GLVT+ED+LE IVG+I+DE+D  D  +  ++ 
Sbjct: 140 MSIAKILQLMQHKHVQMAAVADEYGGTAGLVTMEDLLEEIVGDIQDEHDT-DMPEINKMP 198

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
             ++    L  +++ +E  G  F D E DTIGG V    G  P  G++++ +G +F+V  
Sbjct: 199 DGSYVFDGLVLLDEVSEIMGIQFDDPEEDTIGGYVFGLIGRQPVVGDSVEENGCKFEVLD 258

Query: 269 ADSRRIIQVHVKIPDDSPQPKL 290
           +   R+++V V       +   
Sbjct: 259 STGFRVLRVRVIPLKKEKKEAA 280


>UniRef50_C9L5N7 Hemolysin-related protein n=1 Tax=Blautia hansenii DSM 20583
           RepID=C9L5N7_RUMHA
          Length = 463

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 83/286 (29%), Positives = 163/286 (56%), Gaps = 15/286 (5%)

Query: 19  FSLLLSQLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
            S ++ +LF  +P         +E+++++ D+ +  +I+E+  +M++ +M+ ++   +DI
Sbjct: 171 LSNVVVRLFGVDPHKQEDDVTEEEIISMVDDAHEQGVIEENEAEMIQNIMEFSETEAQDI 230

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR----S 128
           M  R  +  ++ N  L + L  ++++++SR+PV  ED D+I GIL  KD++  +      
Sbjct: 231 MTHRKNLHAIEENTLLKDALSYMLDNSNSRYPVYREDIDNIIGILHLKDVMRQITLPECE 290

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           +    S+  ++R+AV VPE++ ++ + K  ++++ H+ +V+DE+G  SG+VT+EDILE I
Sbjct: 291 NLPIGSIPNLVREAVYVPETRSINDLFKRMQAKKIHLVVVVDEYGQTSGIVTMEDILEEI 350

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VG I DEYDE+++   +  +  +  +  L  +E  ++   + F +EE DT+ G +    G
Sbjct: 351 VGNILDEYDEDENF-IQLQNDQSLVMNGLTPLEQVDDVLNSDFDEEEFDTLNGYLTSLLG 409

Query: 249 HLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           H+P   E   I   GY F +   ++  I +V V+   D  + K +E
Sbjct: 410 HVPNMAEDKEIKAKGYLFTILAVENNTIQKVRVEKLPD--EEKGEE 453


>UniRef50_D1AFV9 Putative uncharacterized protein n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1AFV9_SEBTE
          Length = 428

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 79/253 (31%), Positives = 158/253 (62%), Gaps = 2/253 (0%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H E    DE++ L+ ++ ++ L++++   +++ V +++++ V  +MIPR+ M  +     
Sbjct: 176 HEEIHTNDEIMLLLTENYKHGLLNKEELTLVDNVFELSEKNVMSVMIPRTDMQCIYMGDN 235

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           L++ +D +++  ++R+PV  E+KD+I G +  +DL   +  + E   ++ ++R+ + VP+
Sbjct: 236 LEKIMDFVLDGKYTRYPVCRENKDNIIGFVHIRDLCKQVILNTEN-DIEDIMREIIFVPD 294

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  V+ + K F+     +AIVIDE+GG +GLVT+EDILE +VGEI+DE+D  D  + +++
Sbjct: 295 TMSVNALFKRFQEDHSQIAIVIDEYGGTAGLVTLEDILEELVGEIQDEFDINDVSEIKKI 354

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
           S   ++V    +I+  N+    +    +V+TIGGL    +G LP  GE I  DGY+F + 
Sbjct: 355 SDTVYSVDGKVTIDRINKLLNINIET-KVETIGGLFSLEYGSLPEAGEKIIHDGYEFTII 413

Query: 268 MADSRRIIQVHVK 280
            ++++R+++V ++
Sbjct: 414 KSNNKRVLRVKIE 426


>UniRef50_B2V0V1 CBS/transporter domain protein n=18 Tax=Clostridiales
           RepID=B2V0V1_CLOBA
          Length = 439

 Score =  296 bits (759), Expect = 6e-79,   Method: Composition-based stats.
 Identities = 84/259 (32%), Positives = 152/259 (58%), Gaps = 4/259 (1%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  +++E+ +L+    ++ +I+E  ++M+  + +  D+   ++M PR+++  +  ++ L+
Sbjct: 182 EKVSKEEIKSLVEVGQEHGVINETEKEMINSIFEFDDKLADEVMTPRTEVYLINIDKPLE 241

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKD-LLPFMRSDAEAFSMDKVLRQAVVVPES 148
           E LD ++E  +SR PV  ED D+I GIL  KD +L   + + E  ++ ++L     VPE+
Sbjct: 242 EYLDELLEEKYSRVPVYEEDIDNIIGILYMKDFILEARKHEFENVNIREILHPPYFVPET 301

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K +D +  E +S + HMAI+IDE+GG SG+VTIED++E ++G I+DEYDEE+    +++ 
Sbjct: 302 KNIDDLFNELKSSKKHMAILIDEYGGFSGIVTIEDLVEEVMGNIDDEYDEEE-CFVQKID 360

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET--IDIDGYQFKV 266
            +T+ V  L  I+D N+        +E DTI G ++   G +P   E   I+ +   FK+
Sbjct: 361 SNTFIVNGLMPIDDLNDYLHIQLVSDECDTISGFLINIMGKIPNNIEEKVIEYENIIFKI 420

Query: 267 AMADSRRIIQVHVKIPDDS 285
                +RI ++ + I  D 
Sbjct: 421 ESIKEKRIEKIKICIQKDK 439


>UniRef50_Q2FTJ8 Putative uncharacterized protein n=4 Tax=Methanomicrobiales
           RepID=Q2FTJ8_METHJ
          Length = 429

 Score =  296 bits (759), Expect = 6e-79,   Method: Composition-based stats.
 Identities = 82/265 (30%), Positives = 152/265 (57%), Gaps = 7/265 (2%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +E+   I    +   I++D ++ML  V + +D RVR++M PR  ++ L+   + DE 
Sbjct: 164 ITEEEIKEWIDVGQEEGTIEKDEQEMLHSVFEFSDTRVREVMTPRIDVVMLEDTSSSDEA 223

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           L++   +  SR P+   + D I+GIL  KD +  +    E+  + ++L + + VPE+K +
Sbjct: 224 LEIFKNTGFSRLPIWHGNIDTIKGILNVKDAIFSVLETHESIPIVELLSEPLFVPETKNI 283

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D +L+E R+++ HMAIV+DE+G   G+VT+EDILE +VG+I DE+D E+  +  +++   
Sbjct: 284 DDLLRELRAKKTHMAIVLDEYGSFVGIVTVEDILEELVGDILDEFDTEEH-ELVRVAEDV 342

Query: 212 WTVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAFGHLPARGETIDI--DGYQFKVAM 268
           ++V A   +ED N+    H    E  +TI GLV++  G++P  G+  D+  +G +  +  
Sbjct: 343 YSVDARMWVEDLNKHLDLHLPTSETYETIAGLVIERLGNIPRIGDVCDLTEEGVRLVIIQ 402

Query: 269 ADSRRIIQ---VHVKIPDDSPQPKL 290
              +RI +   + +  P+ S + ++
Sbjct: 403 MTGKRINRLKLIRIHPPEPSDEQEM 427


>UniRef50_Q1YQV9 Magnesium and cobalt efflux protein CorC n=1 Tax=gamma
           proteobacterium HTCC2207 RepID=Q1YQV9_9GAMM
          Length = 279

 Score =  296 bits (759), Expect = 6e-79,   Method: Composition-based stats.
 Identities = 125/280 (44%), Positives = 190/280 (67%), Gaps = 5/280 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M+D+ + S+   S         +S +F   P++ +++  ++R +    +ID     ++EG
Sbjct: 1   MNDETTTSAAEKS-----IFKRISDVFSQTPRSSEDVADILRSAENESIIDASVLQIMEG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            + ++DQ+ R+IMIPRSQM+ +  + +L++ L V+I S HSRFPV+ E  D I+GIL+AK
Sbjct: 56  ALKVSDQQAREIMIPRSQMVIIDDDFSLEQVLKVVISSQHSRFPVVGESSDDIKGILLAK 115

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           ++LP + S  E+F +  +LR A ++PESKR++ +L+EFR QRYHMAIV+DE+GGVSGL+T
Sbjct: 116 EMLPLLLSGNESFDLKALLRPATIIPESKRLNVLLQEFREQRYHMAIVVDEYGGVSGLLT 175

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IEDILE IVGEIEDE DE ++   +  +  ++ V A+A + +FNE F    +D+E DT+G
Sbjct: 176 IEDILEEIVGEIEDETDEHEEAPIKATTSGSFNVEAIAEVSEFNEFFDVGLADDEFDTVG 235

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
           GLV+ AFG LP   E+ID DG+ FKV   D+R+I Q+ V 
Sbjct: 236 GLVLHAFGRLPEINESIDFDGFTFKVTDGDNRKITQLEVT 275


>UniRef50_D2LDC4 Putative uncharacterized protein n=1 Tax=Rhodomicrobium vannielii
           ATCC 17100 RepID=D2LDC4_RHOVA
          Length = 428

 Score =  296 bits (759), Expect = 6e-79,   Method: Composition-based stats.
 Identities = 87/284 (30%), Positives = 140/284 (49%), Gaps = 13/284 (4%)

Query: 10  DTISNKKGFFSLL-------LSQLFHGEPK-NRDELLALIRDSGQNDLIDEDTRDMLEGV 61
            TIS    FF  L       L+     EP+   +E+ ++I +  +  + ++  ++++E V
Sbjct: 146 ATISTPISFFLRLSTDAVLRLAGPMKAEPEVTEEEVKSMIAEGTEAGVFEKAEQEIIERV 205

Query: 62  MDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKD 121
           + +AD+ VR IM+PR  +I L  N + +   + I  S HSRFPV  +D D   G++ AK 
Sbjct: 206 LSVADRSVRSIMVPRRDIIWLDVNDSEEAIFNDIFSSGHSRFPVCRDDVDETFGVIHAKT 265

Query: 122 LLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
           LL   R   +  +++  +   + V ES  V ++L+ F++   HMAIV+DE G V G+VT 
Sbjct: 266 LLEQCRHGGK-INLEAAIMAPLYVHESTNVLKLLEMFKNTLVHMAIVLDEHGTVQGIVTP 324

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH---FSDEEVDT 238
            DIL  I GE+ +E  +       Q    +W + A   + +       +     D E  T
Sbjct: 325 ADILAGIAGELPEEEADIGQSAV-QREDGSWLLDAQMPVYEVERVLDVNGMAVDDAEYTT 383

Query: 239 IGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           + G V+   GH+PA GE      + F+V   D RRI +V    P
Sbjct: 384 LAGFVLAQLGHIPAVGEKFRWRSWVFEVIDLDGRRIDKVLAFRP 427


>UniRef50_P74409 UPF0053 protein sll0260 n=28 Tax=cellular organisms
           RepID=Y260_SYNY3
          Length = 448

 Score =  296 bits (759), Expect = 7e-79,   Method: Composition-based stats.
 Identities = 77/270 (28%), Positives = 138/270 (51%), Gaps = 6/270 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      L         P   +E+  +I    Q  +IDE  ++M+E V  + D+ V+ +M
Sbjct: 163 STDAVLRLFGITSKEASPITEEEIRVMIEQGAQAGMIDEAEQEMVERVFRLGDRPVKTLM 222

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR+ +  L      +E    I+++ +SRFPV  +  D   G +  KD+L    S  +  
Sbjct: 223 TPRTAIAWLDVESDWEENQQEILDTPYSRFPVGRDSLDECLGFVRVKDILNSQWSGQK-I 281

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           +++++++  + V E+ R   +L+ FR+   H+A++ DE+GG+ GLVT+ D++E IVG I 
Sbjct: 282 NLEEIVQPPLFVAENTRSLHVLEMFRASGTHLALITDEYGGIEGLVTLNDLIEAIVGSIP 341

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFGH 249
           ++ DE  +    Q    ++ +  L  I++F E F     S+EE     T+GG V+++ G 
Sbjct: 342 ND-DEIQEPQIIQREDGSYLLDGLLPIDEFKEIFDIETLSNEEEGHYHTLGGFVIESLGK 400

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHV 279
           +P  G+    D  + +V   D  RI +V V
Sbjct: 401 IPQSGDYFVSDTLRVEVVDMDGIRIDKVLV 430


>UniRef50_A3ZXV1 Hemolysin protein n=1 Tax=Blastopirellula marina DSM 3645
           RepID=A3ZXV1_9PLAN
          Length = 430

 Score =  296 bits (758), Expect = 7e-79,   Method: Composition-based stats.
 Identities = 88/256 (34%), Positives = 149/256 (58%), Gaps = 2/256 (0%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           +  ++ +  +  L++ED R+M+E V+++ D  V D+M  RS++  L    + ++ +  + 
Sbjct: 175 IRTIVTEGLREGLLEEDAREMIESVIELGDIDVADVMTSRSEVDALPIETSWEDVVKFVH 234

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPESKRVDRML 155
           E+  +R P   E  D I G+L  KD+L   ++  A+  S+  + R+A +VP+S  +D +L
Sbjct: 235 ETGRTRIPAYHEGLDQIVGVLYVKDMLSELVKPAADRKSLRDLARKAAMVPKSMPIDELL 294

Query: 156 KEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVR 215
           K+F  +R HMAIVIDE+  V+GL+TIEDILE IVGEI DE+D+ ++ +  ++SR    V+
Sbjct: 295 KQFLRERNHMAIVIDEYHAVAGLITIEDILEEIVGEIVDEHDQNEEEEIVRISRDQAEVQ 354

Query: 216 ALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
             A I+D NE  G      ++ DT+ G+V+     +P  G+ I +D  +  V  AD RRI
Sbjct: 355 GRAHIDDVNEELGLDLPVGDDYDTLAGMVISRLQKIPKTGDRIRVDDVEIVVIAADRRRI 414

Query: 275 IQVHVKIPDDSPQPKL 290
            ++ +   D +  P  
Sbjct: 415 QKLQLTKLDPAESPST 430


>UniRef50_C5PXG9 TlyC family hemolysin n=5 Tax=Sphingobacteriales RepID=C5PXG9_9SPHI
          Length = 437

 Score =  296 bits (758), Expect = 8e-79,   Method: Composition-based stats.
 Identities = 79/256 (30%), Positives = 149/256 (58%), Gaps = 3/256 (1%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           L  L+    ++  +D    ++++ V D  ++ V++IM+PR++++ + ++ T DE ++ + 
Sbjct: 184 LQYLLDKGKESGALDFSEHELIKNVFDFNERIVKNIMVPRTKIVAIDKDATADEFINTVT 243

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLK 156
           E  +SR P+  ++ D I GI+  KD+LP +    E   +  ++R+   +PE+K+++ ++ 
Sbjct: 244 EEGYSRIPIYDDNIDQIVGIVHTKDILPIIVKGKEVV-LKNIMRKPYFIPETKKINDLMA 302

Query: 157 EFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRA 216
           EF+ +R  +AIV+DEFGG +G+VT+EDI+E +VGEI+DEYDEE  +   ++S   + + A
Sbjct: 303 EFQLKRIQIAIVLDEFGGTAGMVTLEDIVEELVGEIQDEYDEETPV-VERISETEYMIDA 361

Query: 217 LASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRII 275
            AS+ D NE       +  + DT+ GLV   F  +P  GE  ++ GY F +     + I 
Sbjct: 362 GASVHDVNEYLPLELPESSDYDTMAGLVSDLFDKIPEVGEYKELYGYTFTIMKKTQQNIE 421

Query: 276 QVHVKIPDDSPQPKLD 291
            V +++ +       +
Sbjct: 422 FVKLELIETPHDEDEE 437


>UniRef50_C4Z1L1 Putative hemolysin n=2 Tax=Bacteria RepID=C4Z1L1_EUBE2
          Length = 293

 Score =  295 bits (757), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 78/284 (27%), Positives = 153/284 (53%), Gaps = 9/284 (3%)

Query: 4   DNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMD 63
           ++ H +D    K         +    E    +E++ ++ +S +  +++E+  +M+  + +
Sbjct: 2   NDGHPADGKEKKFSSLFKRFGRGKRDEDVT-EEIMDMVNESHEQGVLEENEAEMIGNIFE 60

Query: 64  IADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL 123
             +++  D+M  R+ ++ L  + T+ E  D ++E  +SR+PV   D D+I G+L  +DLL
Sbjct: 61  FGEKQASDVMTHRNNIVALDNDITVKEAFDRVMEENYSRYPVYDGDIDNITGVLHIRDLL 120

Query: 124 PFMRSDAEAFSM-----DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
                ++           ++L Q   +PE++ +  + ++ +S + HMAIV+DE+G  +G+
Sbjct: 121 KIYVEESNQSRKLGEVGKEILFQPYCIPETRNISPLFRQMQSDKIHMAIVVDEYGQTAGI 180

Query: 179 VTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDT 238
           +T+EDILE IVG I DEYD+E++      +  ++ +   A +ED     G  F  E++DT
Sbjct: 181 ITMEDILEEIVGNILDEYDDEEE-QIVTDADGSYIIEGQADLEDVEARLGIEFECEDIDT 239

Query: 239 IGGLVMQAFGHLPARGE--TIDIDGYQFKVAMADSRRIIQVHVK 280
           + G ++   G +P  GE   ++ +GY FK     +R I++V V+
Sbjct: 240 LSGFMIYKLGKIPDDGESFEVEYNGYIFKTLEVRNRMILKVKVE 283


>UniRef50_C3L2Y2 Transporter, HlyC/CorC family n=26 Tax=Bacteria RepID=C3L2Y2_CLOB6
          Length = 447

 Score =  295 bits (757), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 72/249 (28%), Positives = 138/249 (55%), Gaps = 3/249 (1%)

Query: 40  LIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA 99
           +I    +  + +   ++M+  + D  +   ++IM PR+ + T+  N +    ++ ++E  
Sbjct: 195 MIDLGEETGVFNSTEKEMINSIFDFDNTLAKEIMTPRTSVFTMDINDSPKNIINNMLEER 254

Query: 100 HSRFPVISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEF 158
           +SR P+  ED D+I GIL  KD+L  + + + +   +  +LR    +PE+K +D + KE 
Sbjct: 255 YSRVPIYDEDIDNIIGILHIKDILSIINKENIKKEDLINILRIPYFIPETKAIDFLFKEM 314

Query: 159 RSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA 218
           ++ + ++AI+IDE+GG SG+VT+ED++E ++G I DEYDE+   +  ++  +T+ + A  
Sbjct: 315 QTSKNYIAILIDEYGGFSGIVTMEDLIEEVMGNIFDEYDEDHTEEIIKMDANTFLLDASI 374

Query: 219 SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA--RGETIDIDGYQFKVAMADSRRIIQ 276
           +I+D NE        E  DT+GG ++   G +P       I  +   FK+    + RI +
Sbjct: 375 TIDDLNEKLNLELPSENFDTLGGFILDITGTIPKCNVNSEIQYNNLIFKIEKVSNNRIEK 434

Query: 277 VHVKIPDDS 285
           + + I + S
Sbjct: 435 IKLYINEKS 443


>UniRef50_B2V0W8 Putative membrane CBS domain protein n=14 Tax=Clostridiales
           RepID=B2V0W8_CLOBA
          Length = 417

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 85/263 (32%), Positives = 142/263 (53%), Gaps = 3/263 (1%)

Query: 18  FFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           F  +L       EP    +EL  ++  S +  +++   ++M+  V D AD +V+D+M+ R
Sbjct: 152 FIKILGGDPKASEPFITEEELKTMVGVSEEEGVLENVEKEMIFNVFDFADLQVKDVMVQR 211

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
             +  L    T D+ L +I E   SR P+ ++  D I GIL  KDLL  + +  E F M+
Sbjct: 212 VDVSALDSEATYDDVLKLIKEEQFSRIPIYNQTIDDIIGILNVKDLL-MLENPRENFKME 270

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
           K +R+     E K++  + KE + +R H+A+V+DE+GG  G++TIED++E IVG+IEDEY
Sbjct: 271 KYIREPYYTFEFKKIVELFKEMKKERNHIAVVLDEYGGTVGIITIEDLIEEIVGDIEDEY 330

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           D+  +     +  + + V     + D  +  G     +E D++GGL++   G +P   E 
Sbjct: 331 DDA-NTSIEVIKDNEYIVDGSVRLHDIGDLIGIDMESDEFDSVGGLIIGELGRMPEEKEE 389

Query: 257 IDIDGYQFKVAMADSRRIIQVHV 279
           I+ D  +F V   D  RI +V +
Sbjct: 390 IECDSMKFIVENIDKNRIKKVRI 412


>UniRef50_B7GEW2 Hemolysin related protein containing CBS domains n=8
           Tax=Bacillaceae RepID=B7GEW2_ANOFW
          Length = 421

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 86/268 (32%), Positives = 143/268 (53%), Gaps = 2/268 (0%)

Query: 16  KGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           K   S L+ Q         +E+  ++  S +  +ID   ++++   +D  D  V +I  P
Sbjct: 150 KKVVSKLVGQRADVPSVTEEEIKVMVNLSEEEGVIDNKEKELVHRSLDFNDILVGEIFTP 209

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  M+ ++ NQ ++E  D+ +   +SR PV   D D++ GIL   D    +    E  ++
Sbjct: 210 RIDMVAVEVNQPVEEIRDIFLRERYSRVPVYEGDIDNVIGILSESDFFSQLVQGKE-VNV 268

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
            ++LR  + V ES R+  +L E +  + HMAIVIDEFGG SGL+T+EDILE IVGEI DE
Sbjct: 269 RELLRTPLFVVESMRISTLLPELQKSKVHMAIVIDEFGGTSGLITLEDILEQIVGEIWDE 328

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
           +DE     F++++ + +   A   +++F    G    +    T+GG V + F  +P  GE
Sbjct: 329 HDEAVK-TFQKINDYEYEFNAELPLDEFCHILGIDELESSSHTLGGWVFEMFERIPTVGE 387

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           + + +     V   ++RRI +V V+I +
Sbjct: 388 SFEYETLTVTVRQVENRRIRKVLVRIRE 415


>UniRef50_Q1K126 CBS domain protein n=2 Tax=Desulfuromonadales RepID=Q1K126_DESAC
          Length = 282

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 93/283 (32%), Positives = 168/283 (59%), Gaps = 5/283 (1%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           T   ++ +   LL    H    + + L  LI  S +  +I+ +  +M   + +  +  VR
Sbjct: 4   TPETRRSWLQRLLGITHHV--TSEEHLQELIHASEEGGIINAEEGEMFSSIFEFGETIVR 61

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           ++MIPR++M +   + +LD  ++++++  HSR PV  E  D I G++ AKDLL F    +
Sbjct: 62  EVMIPRTEMRSCPVDASLDTFIEMVLKFGHSRIPVYEETIDRIVGLVYAKDLLKFWGQPS 121

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
              S+  ++R+   VPE+KR++ +L+EFR+QR H+AI IDE+GG SGL+T+ED++E I+G
Sbjct: 122 HEISLRDLMRKPYFVPETKRIEELLQEFRTQRMHIAIAIDEYGGTSGLITLEDLIEEIIG 181

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEEVDTIGGLVMQAFGH 249
           +I+DEYD +D+    +    T  V A  S+++  + +    F  ++ D++GGL++   G+
Sbjct: 182 DIKDEYDFDDNQLIEET-PGTIVVDARLSLDELEDHYDLPEFERDQFDSVGGLLLHRLGY 240

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           +P  GE + ++  +  V  +D R I ++ V I ++SP+  LD+
Sbjct: 241 VPKPGEEVVVEPLKMVVLQSDERMIHRIRV-IREESPEEPLDD 282


>UniRef50_D1Y8K5 Putative transporter n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y8K5_9BACT
          Length = 430

 Score =  294 bits (754), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 89/274 (32%), Positives = 147/274 (53%), Gaps = 7/274 (2%)

Query: 22  LLSQLFHGE------PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
             S LFH +         RDE+  L+++  ++  I+   R M++GV+   + RV +IM+P
Sbjct: 150 FFSDLFHVDMTLESAVVTRDEIEQLVKNGEESGAIEASERRMIDGVIAFDETRVSEIMVP 209

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  M  L+ N+T+     ++    HSR PV  E  D I G++  KD++P++R+      +
Sbjct: 210 RVSMDALEVNETIAGVASLMQNWEHSRIPVFRETPDDIVGVVYLKDMIPYLRAGKMDTPL 269

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
              +R+A+ VPE+ +V  +    R +  H A+V+DE+GG +G+VT+ED+LE IVG+I DE
Sbjct: 270 SAFMRRALFVPETMKVADLFGMMRGKHVHFAVVVDEYGGTAGIVTLEDLLEEIVGDIRDE 329

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
           YDEE      QL+ +++ V+   S+ED     G  F   +VD++GG V+  F   P +G+
Sbjct: 330 YDEE-SAPIVQLNENSYRVKCTESLEDLGAVVGYDFDCNDVDSVGGYVLDKFMGFPEKGD 388

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
               D +  KV      R+ +V         Q +
Sbjct: 389 IYRDDDWTIKVTDVGEHRVNEVIFTRSAHEVQKE 422


>UniRef50_B8JAD7 Putative uncharacterized protein n=4 Tax=Anaeromyxobacter
           RepID=B8JAD7_ANAD2
          Length = 464

 Score =  294 bits (754), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 87/300 (29%), Positives = 149/300 (49%), Gaps = 30/300 (10%)

Query: 9   SDTISNKKGFF-SLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           S  ++   G+    L            +E+  LI    +  ++DE   ++L  V++ AD+
Sbjct: 148 SAAVTRLTGWVVGRLGGGRAPTPAVTSEEIEYLIEMGTREGVLDEVKEELLNSVLEFADR 207

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
             +++MIPR++M+ + R    DE + ++ E+ +SR PV     D++ GIL+ +D++  +R
Sbjct: 208 VAKEVMIPRTRMVAVDRAVEPDELVRIVTENPYSRMPVYEGSIDNVVGILLVRDIIQELR 267

Query: 128 SDA-EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
                  ++D+ L+ A  VPE  ++ R+LKE + +R H+A+V+DEFGG SGLVT+ED++E
Sbjct: 268 HGPLRRIALDRYLKPAFFVPEQMKISRLLKEMQRRRTHLAVVVDEFGGTSGLVTMEDVIE 327

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG------------------ 228
            IVGEI+DE D E     + ++   W   A   + D                        
Sbjct: 328 EIVGEIQDEADVE-SAPVKAVAPGVWLADAAIPLHDLQSFLNEQREEPAPRPAGDDAPEP 386

Query: 229 --------THFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
                     F ++ + +T+GG V    G +P  G T+  DG  F V   D RR+ +V +
Sbjct: 387 EDGEPPPEIRFPEQGDYETLGGFVTATAGRVPPVGATLAWDGLTFTVRAGDERRVTRVEI 446


>UniRef50_P67130 UPF0053 protein Rv2366c/MT2435 n=36 Tax=Actinomycetales
           RepID=Y2366_MYCTU
          Length = 435

 Score =  294 bits (753), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 90/268 (33%), Positives = 148/268 (55%), Gaps = 5/268 (1%)

Query: 26  LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRN 85
             +G   +  EL  ++  + Q  ++  D R M+E V ++ D   R++M+PR++MI ++ +
Sbjct: 157 FRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPAREVMVPRTEMIWIESD 216

Query: 86  QTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM---RSDAEAFSMDKVLRQA 142
           +T  + + + + S HSR PVI E+ D I G++  KDL+       +     ++ +V+R A
Sbjct: 217 KTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYLKDLVEQTFCSTNGGRETTVARVMRPA 276

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
           V VP+SK +D +L+E +  R HMA+++DE+G ++GLV+IED+LE IVGEI DEYD+ +  
Sbjct: 277 VFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETA 336

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDG 261
               L    + V A   IED  E +G  F D+ +VDT+GGL+    G +P  G  +   G
Sbjct: 337 PVEDLGDKRFRVSARLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHG 396

Query: 262 YQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            +         R  +V +     SP   
Sbjct: 397 LRLHAEGGTDHR-GRVRIGTVLLSPAEP 423


>UniRef50_C7RRT5 CBS domain containing protein n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RRT5_9PROT
          Length = 281

 Score =  294 bits (753), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 132/283 (46%), Positives = 188/283 (66%), Gaps = 4/283 (1%)

Query: 8   SSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
            S + S K GFF  L S L   EP++R++L+ L+  + Q  L+D D   + EG +  ++ 
Sbjct: 2   DSSSPSGKPGFFERLSSLLVR-EPEDREQLVQLLHAAHQRKLLDADALSITEGALAASEM 60

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
            VR++M+PR QM  +    TLD+ +D +  +AHSRFPVI+ D+DH+ GIL+AKDLL   R
Sbjct: 61  IVREVMVPRPQMEVVDVGDTLDDVIDRVNTTAHSRFPVINGDRDHVVGILLAKDLLRVRR 120

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
                F++ + +R AV +PE KR+D +L+EFR  R HMAIVIDE+ G++GL+TIED+LE 
Sbjct: 121 D--APFNLREWVRPAVFIPEFKRLDVLLREFRVSRNHMAIVIDEYAGIAGLITIEDVLEQ 178

Query: 188 IVGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
           IVGEIEDEYD +E D + +      + V+A A++ DFN A GTHFSDE+ +T+GGLV+  
Sbjct: 179 IVGEIEDEYDFDEADENIQLDQNGLYRVKAHAAVADFNAALGTHFSDEKCNTVGGLVLHH 238

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            G +P   ETI IDG +F+V  ADSRRI  + V  P ++  P+
Sbjct: 239 LGRVPQFNETIVIDGTRFQVLRADSRRIYTLIVTRPPEADSPE 281


>UniRef50_A0PYY8 Integral membrane protein with CBS domains n=15 Tax=Clostridiaceae
           RepID=A0PYY8_CLONN
          Length = 422

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 78/260 (30%), Positives = 140/260 (53%), Gaps = 2/260 (0%)

Query: 12  ISNKKGFFSLLLSQLFHGEPK-NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           ++       +   +   G+P    +EL  ++  S +  +++ + R M+  V +  D +V+
Sbjct: 149 VALTNKIVGIFGGKASMGKPHITEEELKTIVDVSHEEGVLEVEERKMIYNVFEFGDSQVK 208

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           D+M+PR++M ++  + T DE L+V+ +   SR PV  +  D+I GIL  K L+ F  +  
Sbjct: 209 DVMVPRTEMASVDIDSTYDEILEVLKKEQFSRIPVYKDSTDNIIGILHIKKLV-FFDNSK 267

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           E F + K + +     E K    + +E R  R  M +V+DE+GG +G+VT+ED++E IVG
Sbjct: 268 EKFDITKYMVKPYFTYEYKPTTELFEEMRKDRVAMTVVLDEYGGTAGIVTMEDMVEEIVG 327

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           +IEDEYD E + + + +    + V+    I++ NE  G     E+ D+IGG V+   G  
Sbjct: 328 DIEDEYDNEQNDEIKLIKDDEYIVKGSTKIDEVNEMLGIDIESEDFDSIGGFVIGEVGRF 387

Query: 251 PARGETIDIDGYQFKVAMAD 270
           P +GE ++ D  +  +   +
Sbjct: 388 PKKGEFVEYDDVKLIIEEIE 407


>UniRef50_B9ZL46 CBS domain containing protein n=2 Tax=Gammaproteobacteria
           RepID=B9ZL46_9GAMM
          Length = 311

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 135/295 (45%), Positives = 195/295 (66%), Gaps = 6/295 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLE 59
           M +       T    + +     ++L    +P  R EL+  +RD+   +L+D +   MLE
Sbjct: 1   MPEPVPDEQPTW---RRWLERAKTRLWPRRDPATRRELIETLRDAHGRELVDPEALTMLE 57

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
           GV+++AD +VRDIMIPR+QM  ++R+  L E L  ++ SAHSR PV+ + +D + G+L+A
Sbjct: 58  GVLNVADMQVRDIMIPRAQMEVVRRDARLSEFLPDVVASAHSRLPVVGDHRDEVVGVLLA 117

Query: 120 KDLLPFM-RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           KDLL F    D  AF M ++LR AV VPESKR++ +LKEFR  R HMAIV+DE+GGV+GL
Sbjct: 118 KDLLRFFGEPDDAAFDMQEILRPAVFVPESKRLNVLLKEFRLSRNHMAIVVDEYGGVAGL 177

Query: 179 VTIEDILELIVGEIEDEYDEEDDI-DFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           VTIED+LE IVGEIEDE+D ED +    Q     +T++AL  +E+FN  F T +S+++ D
Sbjct: 178 VTIEDVLEQIVGEIEDEHDVEDYLTQIMQHPGGRYTIKALTPMEEFNAYFQTAYSEDDFD 237

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           TIGGLV+  FGH+P RGE I IDG +F+V  AD+RR+  + +++P+    P  D+
Sbjct: 238 TIGGLVLSHFGHVPRRGEQIVIDGMRFRVLRADNRRLHLLEMRLPEPDVAPASDD 292


>UniRef50_B5YET1 GldE n=2 Tax=Dictyoglomus RepID=B5YET1_DICT6
          Length = 377

 Score =  292 bits (750), Expect = 7e-78,   Method: Composition-based stats.
 Identities = 87/251 (34%), Positives = 143/251 (56%), Gaps = 5/251 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
             DE L L+    +  +I+++ ++++  V++  D  V +IM+PR  M+ +  +  L E  
Sbjct: 114 TVDEFLTLVNVGEKEGIIEKEEKELISNVLEFTDTEVHEIMVPRIDMVCVSVDSPLKEVW 173

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
             IIE  HSR PV     D+I GI+ AKD+L  +        +  +LR  + VPE+ +++
Sbjct: 174 KKIIEEGHSRIPVYEGSIDNIVGIVHAKDVLKALAEKDPNVKIKDILRDVIYVPENMKIN 233

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +  E R ++ H+AIV+DE+GG +GLVT+ED+LE +VGEIEDEYD+E++  F  L  +T 
Sbjct: 234 ELFNEMRKKKAHLAIVVDEYGGTAGLVTLEDVLEELVGEIEDEYDKEENK-FNFLDENTL 292

Query: 213 TVRALASIEDFNEAF----GTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
            V A  +I + N+      G    + E DT+GGL++     +P+RGE ID+      +  
Sbjct: 293 IVDAKMNIYELNDILEETWGITLPETEYDTLGGLILDLLNRVPSRGEQIDLGDLIIVIES 352

Query: 269 ADSRRIIQVHV 279
              +RI +V +
Sbjct: 353 VRRQRIEKVKI 363


>UniRef50_B9Z7Q6 Putative uncharacterized protein n=1 Tax=Lutiella nitroferrum 2002
           RepID=B9Z7Q6_9NEIS
          Length = 440

 Score =  292 bits (749), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 70/279 (25%), Positives = 134/279 (48%), Gaps = 7/279 (2%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
              L+ ++         +E+  L+       + D   ++++E +  + D++V  IM PR 
Sbjct: 160 ILRLMGAKKSKEPSITEEEIKVLMEQGADEGVFDRAEQELVENIFRLDDRKVASIMTPRK 219

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            +I+L           ++    +SR+PV     D + GI+ AK LL  + S   +     
Sbjct: 220 DIISLDIEDDHTSNCQLMQSHPYSRYPVCKGGMDQLIGIVDAKHLLDRLLSGG-SVDFTA 278

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
            +   + VP +  + ++L++F+  R HMA+V+DE+G + GLVT+ D+LE IVG +     
Sbjct: 279 GMHPPLYVPATVSLMQLLEQFKRARIHMALVVDEYGELEGLVTLHDVLESIVGGLPAGPQ 338

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH--FSDEE---VDTIGGLVMQAFGHLPA 252
           E++ +   Q   H+W V  + + ++  E F        E+   + T+GG+VM   G +P 
Sbjct: 339 EDEQLII-QRDEHSWLVDGMVAPDELREHFAIDSLLPGEDTGNIHTLGGVVMFQLGRVPV 397

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
             +  + +G+ F+V   D  R+ +V V     +  P+ +
Sbjct: 398 AADRFEWNGFAFEVVDMDKTRVDKVMVSRLQAASAPEEE 436


>UniRef50_D1C1Y5 CBS domain containing protein n=1 Tax=Sphaerobacter thermophilus
           DSM 20745 RepID=D1C1Y5_SPHTD
          Length = 424

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 95/276 (34%), Positives = 154/276 (55%), Gaps = 9/276 (3%)

Query: 21  LLLSQLFHGEPKNRDELLALIRDSGQND----LIDEDTRDMLEGVMDIADQRVRDIMIPR 76
            L+ +   GE  N ++      ++ +       I+ED ++M+ GV+ + +  VR+IM+PR
Sbjct: 150 RLVRRGAPGEAGNGED----AGEAHEGGNGDLDIEEDEQEMISGVLGLEEATVREIMVPR 205

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
             ++   ++ ++ E +D+   + HSR PV  +  D I G++ AKDLL F+   A    + 
Sbjct: 206 LDIVAAPQDMSISEVVDLARSAGHSRIPVYRDSIDSIVGVIYAKDLLRFVNEQATGVKLL 265

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
            +LR A  VPESK VD +L++ R  + H+AIV+DE+GG +GLVTIEDILE IVGEI+DEY
Sbjct: 266 DLLRPAYFVPESKHVDELLRDMRQAKVHIAIVVDEYGGTAGLVTIEDILEEIVGEIQDEY 325

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           D E  +   +L      V    ++++  + F T F++ E  TIGG V +  G +P  GE+
Sbjct: 326 DRETPL-IERLGAEEVIVDGRIAVDEIADIFETEFAEGETGTIGGFVQKRLGRIPKAGES 384

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           +  DG   +V   +  RI ++ V    +      +E
Sbjct: 385 LRADGLLIEVQAVEHHRIRKLRVVRVREDGTAVSEE 420


>UniRef50_B6IU27 CBS domain protein n=2 Tax=Rhodospirillum RepID=B6IU27_RHOCS
          Length = 434

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 74/278 (26%), Positives = 138/278 (49%), Gaps = 5/278 (1%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           ++ +    LL            +E+ +LI +   + + + + + M+EGV+ ++D+ VR I
Sbjct: 158 ASTEAMLKLLRIPDRPDSTVTEEEVKSLIAEGTASGVFEPEEKRMIEGVLRLSDRTVRSI 217

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR  +  L  +   D     I E+ HSR+ V   D D + G++  +DLL    +    
Sbjct: 218 MTPRLDVDWLDVDADPDSLRRDIQEAGHSRYVVCRGDLDDVVGVVHIRDLLEAQFAG-RP 276

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +    R A+VV +   V R+L+ F+     +A+ +DE+G V G+ T+ D++E I G++
Sbjct: 277 LDLRAATRDALVVHDGTEVMRLLELFKKTGQQIAVAVDEYGSVEGVATLTDVMEAIAGDL 336

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAF---GTHFSDEEVDTIGGLVMQAFGH 249
            +  +E ++ D  + +  ++ +  + ++E+             D E  TI G V+   GH
Sbjct: 337 PEAGEEGEEADVVRRADGSYLIDGMLAVEEVESLLSLRSLRDEDGEYHTIAGFVLFKLGH 396

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHV-KIPDDSP 286
           +P  GE    DG++F+V   D+RRI +V V ++    P
Sbjct: 397 IPKAGEGFSHDGWRFEVVDMDARRIDKVMVSRLTQQEP 434


>UniRef50_B9L251 Magnesium and cobalt efflux protein corC n=1 Tax=Thermomicrobium
           roseum DSM 5159 RepID=B9L251_THERP
          Length = 420

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 90/229 (39%), Positives = 135/229 (58%), Gaps = 1/229 (0%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           ++E V+ +     RDIM+PR+ ++ +    ++ + + V  ++ HSR PV     D I GI
Sbjct: 183 LIERVLRLDRLTARDIMVPRTDIVAVPFELSVRDAIAVARQTRHSRLPVYQGTIDRIVGI 242

Query: 117 LMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           +  +DLL F    AE   +  V+R+A  +PESKRVD +L++ + QR HMAIV+DEFGG +
Sbjct: 243 VHVRDLLRFALESAEGIKVGDVMREAYFIPESKRVDELLRDLQHQRVHMAIVVDEFGGTA 302

Query: 177 GLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEV 236
           G+VTIED+LE IVGEI+DEYD E  +   +LS     V    S+E+  + FG    +EE 
Sbjct: 303 GIVTIEDVLEEIVGEIQDEYDAEAPL-VERLSADEAIVDGRISLEEIADIFGVSLEEEES 361

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            TIGGLV    G +P  GE++ +DG +  V      R+ ++ V+    S
Sbjct: 362 STIGGLVQAHLGRIPQPGESVRVDGLEVTVLEVAGNRVRKLSVRRVAAS 410


>UniRef50_A5EY48 Transporter associated domain protein n=2 Tax=Cardiobacteriaceae
           RepID=A5EY48_DICNV
          Length = 288

 Score =  291 bits (747), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 131/293 (44%), Positives = 189/293 (64%), Gaps = 6/293 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDE-LLALIRDSGQNDLIDEDTRDMLE 59
           M+D+ S S  +   K    +LLL+     +P+N  +    L+ D   N  I++DT  M+E
Sbjct: 1   MNDEFSGSKSSWLKK---LALLLTD--KTQPENPQDAFHLLLDDYRHNQTINDDTATMME 55

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
            ++++    VRD+MIPR QM+ +  + +LD+ L VII+S HSR+PVI E  + I GIL+ 
Sbjct: 56  SLLELNHTHVRDVMIPRGQMVVIHEHWSLDKVLSVIIQSGHSRYPVIDESHEKILGILIT 115

Query: 120 KDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           KDLLP +  D E  +   V+R A VVPESK +D ML++FR+ R HMAIVIDE+G +SGLV
Sbjct: 116 KDLLPILVDDDENPNFMAVIRSATVVPESKPLDAMLRDFRTNRNHMAIVIDEYGNLSGLV 175

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED++E IVGEI+DE+D+  D + R L   ++ V+AL  IE FNE F TH  DE+ DTI
Sbjct: 176 TIEDVIEEIVGEIDDEHDQIPDAEIRTLPDGSYQVKALMMIEHFNEQFQTHLPDEDADTI 235

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           GG ++  FG +P  GE + IDG++  V+ A+ RRI+Q+ V   ++    K +E
Sbjct: 236 GGYLLHYFGRIPINGERLSIDGWEIIVSKANQRRILQLKVVATNEEHTEKAEE 288


>UniRef50_C8VVX2 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C8VVX2_DESAS
          Length = 446

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 84/259 (32%), Positives = 147/259 (56%), Gaps = 6/259 (2%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H    +  EL  L+ +S ++  +D+D   +L+ V +   +  R+I++PR +++ L R +T
Sbjct: 185 HEASHSEKELQMLVSESYKSGHLDKDEWRLLQNVFEFEKRIAREILVPRPEVVFLDRRKT 244

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           L + +++  +S H+RFP+   D D++ G++  KDL        +  S++ V R  ++VPE
Sbjct: 245 LQQNIEIARQSEHTRFPLCDGDNDNVVGLIHIKDLFKL----KDETSINDVKRNIMMVPE 300

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
              +DR+LK+F+  R  MA+V+DE+GG SG+VT+ED+LE +VGEI DE+D E      + 
Sbjct: 301 GIPLDRLLKQFQQCRQQMALVVDEYGGTSGIVTMEDVLEKLVGEIHDEFDNEIPKIIPE- 359

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
              T+ V     +E+  E F    +++ E DTIGG V    G  P  G+ +++  ++ +V
Sbjct: 360 KEGTFLVEGRLLLEEAKEMFHLPVTEDTEYDTIGGYVFGELGKRPKVGDIVELPNHRLEV 419

Query: 267 AMADSRRIIQVHVKIPDDS 285
                 RI Q+ + I D+ 
Sbjct: 420 TRIQGLRIQQIRLNILDNK 438


>UniRef50_C5EUB4 Membrane-anchored CBS domain-containing protein-domain containing
           protein n=5 Tax=cellular organisms RepID=C5EUB4_9FIRM
          Length = 496

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 80/284 (28%), Positives = 148/284 (52%), Gaps = 17/284 (5%)

Query: 12  ISNKKGFFSLLLSQLFHGEP------KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIA 65
           ++      S L+ +LF  +          +++++++ +  +  +++ D  +M+  + ++ 
Sbjct: 160 LTRLITLVSALVLRLFGVDIADDDDNVTEEDIMSMVNEGHEQGVLEADETEMITNIFELG 219

Query: 66  DQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA-HSRFPVISEDKDHIEGILMAKDLLP 124
           D+   DIM  R+ M  L  +  L + +  I+    ++R+PV  ED D I GIL  +D + 
Sbjct: 220 DKEASDIMTHRTNMTALDGSMLLGDAVHFILNEGINTRYPVYREDIDDIVGILHMRDAMV 279

Query: 125 FMR----SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           ++      D     +  +LR+A  +PE++ +D + KE +S + HM IV+DE+G  +GL+T
Sbjct: 280 YVEMEEYKDRPLLEVPGLLREANFIPETRSIDTLFKEMQSGKIHMEIVVDEYGQTAGLLT 339

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VD 237
           +EDILE IVG I DEYDEE+D         ++ +  L  ++D  +     F +E+    D
Sbjct: 340 MEDILEEIVGNIMDEYDEEEDF-ISVREDGSFIMSGLTPLDDVMDVLDIEFPEEDSDTYD 398

Query: 238 TIGGLVMQAFGHLPARGE--TIDIDGYQFKVAMADSRRIIQVHV 279
           T+ G ++     +P  GE   +   GY F+V  A ++ I  +HV
Sbjct: 399 TLNGYLISRLDRIPQEGENPRVGFGGYTFEVIKAGNKMIESIHV 442


>UniRef50_Q2NIR0 Hymolysin-related protein n=5 Tax=Candidatus Phytoplasma
           RepID=Q2NIR0_AYWBP
          Length = 423

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 72/257 (28%), Positives = 140/257 (54%), Gaps = 6/257 (2%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
            + DEL  ++  S Q  +ID+D   M++ + +     + ++M  R++++ +    T  E 
Sbjct: 165 ISEDELRLMLISSYQKGIIDKDENKMIQNIFEFDHTNIFEVMRHRTEVVAIDVEITKKEL 224

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD--AEAFSMDKVLRQAVVVPESK 149
           +  I    ++RFPV     D+I GIL  KD+  ++ S    + F + K +R+  +V +++
Sbjct: 225 IKTIQNEKYTRFPVYENSIDNIIGILHIKDIFNYLMSSNTNKIFDLKKFIRKPYLVQDAQ 284

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
               + +E +  + HMAIVIDE+GG +G++T ED++E I+GEI DEYD E+ +  +++++
Sbjct: 285 NTREIFREMKKNKTHMAIVIDEYGGTAGIITFEDLIEEILGEISDEYDNEE-LMIKEVAK 343

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE---TIDIDGYQFKV 266
           + + V   A +E+  E     F+ E+ DT+ G ++   G  P + +    I    ++FK+
Sbjct: 344 NEYIVNGFADLEEVAETIKLEFNTEDYDTLSGFLIGKLGRCPNQNDKNTEIIYKNFKFKI 403

Query: 267 AMADSRRIIQVHVKIPD 283
              + + I Q+ +   D
Sbjct: 404 LKHNDKVISQIKISKID 420


>UniRef50_C6W3X5 Putative uncharacterized protein n=1 Tax=Dyadobacter fermentans DSM
           18053 RepID=C6W3X5_DYAFD
          Length = 430

 Score =  290 bits (744), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 86/263 (32%), Positives = 145/263 (55%), Gaps = 3/263 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           ++     E  + DEL  L++    + +I+    D+++   D +++  R IMIPR Q++ +
Sbjct: 170 ITPSHGSEVHSSDELRYLVQQQKDSGMIEAADYDLIKNAFDFSERIARQIMIPRPQVVGI 229

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQA 142
             N   +  L+ +IE  +SR PV  +  D + G+L  KDLL  MR   +   + +++R  
Sbjct: 230 DVNDFTEAKLEKVIEEGYSRMPVYEDTLDQVIGVLHLKDLLLKMRQGKDIV-LRELIRPI 288

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
             V  SK +  +L+EF+  R  MA+++DE+GGV G+VT+EDILE +VGEI+DEYD E  I
Sbjct: 289 ATVHGSKPIGALLREFQVSRQQMAVIVDEYGGVDGIVTMEDILEELVGEIQDEYDNEAPI 348

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDG 261
             +  S +T+TV+  ASI D N+      +   + +T+ G ++   G +PA GE +    
Sbjct: 349 -VKNESDNTYTVQGAASIADLNDKLPHDITRRPDYETLAGYLIWKCGRIPAVGEKVKTKH 407

Query: 262 YQFKVAMADSRRIIQVHVKIPDD 284
           Y+F V       + QV + + + 
Sbjct: 408 YEFTVLKKQRSSVTQVKIAVLES 430


>UniRef50_C6IW85 Putative uncharacterized protein n=1 Tax=Paenibacillus sp. oral
           taxon 786 str. D14 RepID=C6IW85_9BACL
          Length = 452

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 76/254 (29%), Positives = 135/254 (53%), Gaps = 2/254 (0%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           +  + +EL  L+R+S  N  I++     +  +    D   +DIM+PR+ M+ L   ++ +
Sbjct: 175 DAHSEEELRILLRESLANGRINKSEYRFMNRIFAFDDLLAKDIMVPRTDMVCLDAAKSRE 234

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
           E L +I    ++RFPVI  +KD+I G++  K L      +     +  ++R  + V E+ 
Sbjct: 235 ENLRIIRREQYTRFPVIRGNKDNIIGVINTKALF-LAPENQADVPLASLVRPVMTVSENI 293

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            +  +L + + +R H+A++IDE+GG SG+VTIEDILE IVG+I DE+D E++ +  +++ 
Sbjct: 294 PLPALLTKMQKERSHIAVLIDEYGGTSGMVTIEDILEEIVGDIRDEFDAEEEQEITEVAA 353

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
           +   V    S+   NE       +++ DTIGG +      +   G  +     QF V   
Sbjct: 354 NHLIVDGKVSVSLINELLDADLKEDDADTIGGWIYGHNLDI-EEGTQLVYGDLQFTVLER 412

Query: 270 DSRRIIQVHVKIPD 283
           +  RI ++ +K  D
Sbjct: 413 EDTRIRKIEIKRLD 426


>UniRef50_Q310P2 CBS n=6 Tax=Desulfovibrionaceae RepID=Q310P2_DESDG
          Length = 298

 Score =  290 bits (743), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 93/266 (34%), Positives = 156/266 (58%), Gaps = 3/266 (1%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
              L S+ F    KN D +   I ++  +  +D +   ML  ++ + + +V +IM PR+ 
Sbjct: 35  LWSLFSRFFSA--KNGDSVEQAIIEAQDDGELDSEESTMLLSILRLDEMQVYEIMTPRTD 92

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS-DAEAFSMDK 137
           +       +L + +D+I+ S HSR PV  +++D+I G++ AKDLL  +      +  + +
Sbjct: 93  IDCADDQSSLGDIIDLIVSSGHSRIPVYRDNRDNIIGVVYAKDLLSVLTDTGQRSAPVTE 152

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
            +RQ + VPE+K+V  +L+EFR+++ H+AI +DE+GG SGLVTIED+LE+IVG+IEDE+D
Sbjct: 153 TMRQPIFVPETKKVSELLQEFRTRKNHLAIALDEYGGTSGLVTIEDVLEVIVGDIEDEHD 212

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
                D R L   T  V   A +ED +E  G     ++V+TIGG + +  GH+P  GE+ 
Sbjct: 213 APRQEDIRALDDGTLEVSGRAFLEDLSERLGVLLESDQVETIGGYLSEIAGHVPQAGESF 272

Query: 258 DIDGYQFKVAMADSRRIIQVHVKIPD 283
            +  + + V  AD+++I  + V   +
Sbjct: 273 TVGAHSYTVMEADAKQIKTIRVTPSE 298


>UniRef50_B8J8L5 CBS domain containing protein n=4 Tax=Anaeromyxobacter
           RepID=B8J8L5_ANAD2
          Length = 425

 Score =  290 bits (743), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 90/263 (34%), Positives = 149/263 (56%), Gaps = 4/263 (1%)

Query: 19  FSLLLSQLFHGEPKNRDEL-LALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           +S      F   P   DE+  AL   +G+     E TR+++  V +  ++  RD+M+PR+
Sbjct: 156 WSAGRRARFSLPPPPLDEMERALAEYAGRGGSGSEGTRELIHNVFEFREKVARDVMVPRT 215

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            ++ ++    + + +  + E  HSR PV  E  D I G+L A+DL+P +    E   +  
Sbjct: 216 DVVAVELGTPVPQIIRTLSEEGHSRMPVYRESLDQIAGVLHARDLVPLLAH-PELIVLAD 274

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED-EY 196
           +LR A  VP SK V+++L+E + +  HMA V+DEFGGV G+ TIED+LE IVG+I+D   
Sbjct: 275 ILRPAHFVPWSKPVEQLLREMQRRHLHMAFVVDEFGGVMGICTIEDVLEQIVGDIQDEFE 334

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGE 255
           +E++  +  Q +  ++TV+  A++ +FN A      ++   +T+ G V    G +PARG+
Sbjct: 335 EEDEGREVEQHADGSFTVQGAAAVAEFNRAAQAGVPEDQGFETMAGFVSSLAGAIPARGD 394

Query: 256 TIDIDGYQFKVAMADSRRIIQVH 278
                G+ F VA AD RR+++V 
Sbjct: 395 RFFWKGWVFTVAEADPRRVVKVR 417


>UniRef50_C8X404 CBS domain containing protein n=2 Tax=Desulfovibrionales
           RepID=C8X404_DESRD
          Length = 285

 Score =  290 bits (743), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 97/275 (35%), Positives = 161/275 (58%), Gaps = 4/275 (1%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
            + +G    L+ + F G+ +N   +  +I ++  +  ++     ML  V+ +  ++VR+I
Sbjct: 3   ESPEGKLWTLVRKFFSGKTENP--IEDVILEARTDGELEAFEASMLINVLRMGRKQVREI 60

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           MIPR+ +  +++N ++ +  ++IIE  HSR PV  E+KDHI G++ AKDLLP++ +  E 
Sbjct: 61  MIPRTDIQCVEQNASIQDVAELIIEHGHSRIPVYRENKDHIIGVVHAKDLLPYLLNHCET 120

Query: 133 FS--MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
               +  ++R    +PE+K V  M+ EF++Q+ HMAI +DE+GG SGLVT ED+LE IVG
Sbjct: 121 PPDPLSAIMRPPFFIPETKNVKNMIAEFQAQKVHMAIALDEYGGTSGLVTFEDVLEEIVG 180

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           EIEDEYD     D + +      V    S+ D  E  G   + ++V+TIGG V +  G +
Sbjct: 181 EIEDEYDLPRPEDIQVMEDGRHLVAGRTSLNDLEEETGVSLTSDQVETIGGFVTELAGRV 240

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           P  GE  D  G+ F++  ADS+++  V +    ++
Sbjct: 241 PMTGEEFDYLGHNFRIEEADSKQVYAVSILPRVET 275


>UniRef50_C9KJP9 CBS domain protein n=3 Tax=Veillonellaceae RepID=C9KJP9_9FIRM
          Length = 458

 Score =  289 bits (742), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 89/279 (31%), Positives = 143/279 (51%), Gaps = 7/279 (2%)

Query: 12  ISNKKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           +S   G   LLL    H E     DE+  LI    ++   ++  + M++ +  ++DQ   
Sbjct: 166 LSGSAGGVLLLLGINPHVEDTVTEDEVKDLIEQGTEDGTFEKSEQAMVDRIFHMSDQTAY 225

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
            +M PR+QM+ L    +L   L +I E   + FPV  E+ D   G+L AKDLL     + 
Sbjct: 226 SLMTPRTQMLWLDLTDSLRHNLRIIREHPQNVFPVGRENLDDFCGVLYAKDLLNASL-ER 284

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           ++  + + +R+ + VP S    R+L +FR    H A+V+DE+GGV G +T+ DIL+ I+G
Sbjct: 285 KSLDLAQYIRKPMFVPRSMETFRVLAKFRDTGIHEAMVLDEYGGVVGFITLNDILQEIIG 344

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEE---VDTIGGLVMQA 246
           +      E D I F     H+W V  L SI+DF E F      DE+     T+GG +   
Sbjct: 345 DSMSNV-EPDPIQFTPRDEHSWYVDGLCSIDDFKERFDIAELPDEDHDHYQTMGGFLTSY 403

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           FG++P   E  + +G+ F+V   D  RI ++ V   +++
Sbjct: 404 FGYIPKVAEKCEWNGFTFEVVDMDRARIDKILVTREENT 442


>UniRef50_A8PND0 Magnesium and cobalt efflux protein CorC n=1 Tax=Rickettsiella
           grylli RepID=A8PND0_9COXI
          Length = 289

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 123/274 (44%), Positives = 182/274 (66%), Gaps = 4/274 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           N++ +FS     +F   PKNR +L+ L+  + Q +L++     MLEGV+ I+D +VRDIM
Sbjct: 15  NRQSWFSRF--NVFKQAPKNRKQLIELLHYAKQRNLLNSQALKMLEGVLQISDSQVRDIM 72

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IP +++  +     L E L ++IESAHSRFPVI++++  + G+LMAKDLL +       F
Sbjct: 73  IPHAKITAISAKAPLSEILPLVIESAHSRFPVINDER-QVIGLLMAKDLLKYNPLSQNDF 131

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           ++  +LR  V +PESKR+D +LKEF+ + YHMAIV+DE+G  SGLVTIED+LE IVGEIE
Sbjct: 132 NIHTILRPVVFIPESKRLDSLLKEFQRKHYHMAIVVDEYGAASGLVTIEDVLEEIVGEIE 191

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DE+D +++I  ++ + H + V+A+  IE FN  F +H   ++ DTIGG++   FG+LP R
Sbjct: 192 DEHDTDEEIFIQEQTPHQFIVKAIMPIEAFNAFFNSHLETDQFDTIGGVIANRFGYLPKR 251

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKI-PDDSP 286
           G +  I  + FKV  AD+R I  + V I P + P
Sbjct: 252 GASTTIYPFHFKVLRADNRVIRLLQVTIEPVNKP 285


>UniRef50_C8WNW4 Putative uncharacterized protein n=1 Tax=Eggerthella lenta DSM 2243
           RepID=C8WNW4_EGGLE
          Length = 439

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 83/286 (29%), Positives = 144/286 (50%), Gaps = 12/286 (4%)

Query: 13  SNKKGFFSLLLSQLFH-GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           S   G   +L   + +  E    +E+  LI +S ++ LID +  + ++ + D+ D+    
Sbjct: 159 SITNGVMKMLGHDVANEHEVYTDEEIKLLIDESTESGLIDPEQNEYVDNIFDLGDKDAEA 218

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM PR+ ++ +  +  L+E L  +++  ++R+PV    KD I G +  KDL   M  DA 
Sbjct: 219 IMTPRTDVVCIDLDDPLEESLQTVLQYKYTRYPVCRGSKDRIVGFVHVKDLYT-MPKDAT 277

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +   +R    VPE   + ++L+  + +R  +A+VIDE GG +G+VT+ DI+E IVG 
Sbjct: 278 VDDLR--VRMIQAVPEGVPIAKLLQTLQEKRTKIAVVIDEHGGTAGIVTMSDIMEQIVGR 335

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEEVDTIGGLVMQAFGHL 250
           I+DEY      +  QL   ++ +     I++  E  G      EE +T GGL++  F  +
Sbjct: 336 IDDEYAHGGSDEIVQLDDGSYLIDGSLPIDEVGELIGFEPLESEECETAGGLLLTVFDRI 395

Query: 251 PARGETIDIDG----YQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           P  G+++ I+       F V   D  RI ++ V +      P+ DE
Sbjct: 396 PDEGDSVTIEDGDDRATFTVVDMDRHRIDKIRVVL---EHAPESDE 438


>UniRef50_C7DFD3 CBS domain protein n=6 Tax=Rhodobacteraceae RepID=C7DFD3_9RHOB
          Length = 456

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 81/281 (28%), Positives = 149/281 (53%), Gaps = 17/281 (6%)

Query: 18  FFSLLLSQLFHG--EPKN-----RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           +F   + ++F    +P +     R+E+   ++      +++++ RD + G +D+AD+ V 
Sbjct: 167 WFVRGVLRIFGVKIDPDSNVLAVREEIQGALQLGHSEGVVEKEDRDRILGALDLADRTVE 226

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM---- 126
           +IM+ RS +  +    T ++ L+  + S H+R P+  ++ ++I G++ AKDLL  +    
Sbjct: 227 EIMLHRSGIEMIDAGNTPEDILNQCLASKHTRLPIYKDEPENIIGVIHAKDLLRAVNTLL 286

Query: 127 ------RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
                  S    F++ +V  +   VPE+  +D  +++F ++  H A+V+DE+G + GL+T
Sbjct: 287 RTPGEDASSLADFNVIEVAMEPYFVPETTPLDDQMRQFLARHTHFALVVDEYGALQGLIT 346

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           +EDILE IVGEI DE+D  +D    Q    T+ V    +I D N A      D+E +T+ 
Sbjct: 347 LEDILEEIVGEITDEFDGGEDNQLAQSDDGTFMVEGNMTIRDLNRANDWSLPDDEANTVA 406

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           GLV+     +P  G+     G++F+V      RI  + V+ 
Sbjct: 407 GLVIHEAQMIPTVGQVFSFHGFRFEVTEKQKNRIATLKVRP 447


>UniRef50_C6NUU3 Magnesium and cobalt efflux protein CorC n=1 Tax=Acidithiobacillus
           caldus ATCC 51756 RepID=C6NUU3_9GAMM
          Length = 292

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 112/285 (39%), Positives = 178/285 (62%), Gaps = 5/285 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S    + S     +    +Q   G  +++D LL LIR++G+  +ID +   M++G
Sbjct: 1   MSEDRSSPERSRS-----WWARFTQSLRGNVEDQDTLLDLIREAGERQVIDAEAARMVDG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           +  + +  VRD+MIPR+QM  ++ +  + E +  ++E  HSRFPV+  D+D + GIL+AK
Sbjct: 56  IFRMGELSVRDVMIPRAQMEVIELDLPIPEIIARVVEVGHSRFPVVGNDRDDVRGILLAK 115

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL       E   + ++LR A  +PESK +D +L EFR+ R+HMA+V+DE+GGV+GL+T
Sbjct: 116 DLLRACGQGQEPPRLTELLRPATFIPESKHLDHLLYEFRTGRHHMALVVDEYGGVAGLIT 175

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IED+LE+IVGEIEDEYD E+D+         + V A+ ++ +FN  F T+  DE  DT+G
Sbjct: 176 IEDVLEIIVGEIEDEYDIEEDVMVVPREDGDFLVNAVITLPEFNTQFHTNLDDEYADTLG 235

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           G +    GH+P  GE + +DG + +V  AD +R+  + + +P  +
Sbjct: 236 GWLSNRLGHVPRVGEVVMVDGLRLEVLRADRKRVQILRLSLPRAA 280


>UniRef50_A8KYW4 CBS domain containing protein n=33 Tax=Actinomycetales
           RepID=A8KYW4_FRASN
          Length = 484

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 98/262 (37%), Positives = 150/262 (57%), Gaps = 5/262 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   +  EL  L+  + +N++I+ + RDM+  V ++ D  VR++M+PR  M+ ++ ++T+
Sbjct: 163 GPFASEAELRDLVDLAEENEVIEPEERDMIASVFELGDTLVREVMVPRPDMVFIESDKTV 222

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
            + + + + S  SR PVI E  D + GI   KD++ + R   E+  + +V+R  V+VPES
Sbjct: 223 RQAISLALRSGFSRIPVIGESIDDVVGIGFLKDMVGWEREGRESSRVAEVMRPPVLVPES 282

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K  D +L+E ++ R HMAIVIDE+GG +GLVTIED+LE IVGEI DEYD         L 
Sbjct: 283 KPADDLLREMQASRTHMAIVIDEYGGTAGLVTIEDVLEEIVGEITDEYDSATPP-VEWLD 341

Query: 209 RHTWTVRALASIEDFNEAFGT-HFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
             T  V A   ++D  + FG       ++V+T+GGL+  A G +P  G T D+ G +   
Sbjct: 342 DDTARVTARLDVDDLADLFGVEELPGAQDVETVGGLLANALGRVPIPGATADVAGLRLSA 401

Query: 267 AMADSRR--IIQVHVKIPDDSP 286
             A  RR  I  V V     +P
Sbjct: 402 ERAAGRRNQIGTVVVHRLSPAP 423


>UniRef50_D1AH17 Putative uncharacterized protein n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1AH17_SEBTE
          Length = 424

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 90/269 (33%), Positives = 149/269 (55%), Gaps = 4/269 (1%)

Query: 14  NKKGFFSLLLSQLFHGE--PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +   FFS L +   + +      D +   +    ++  I+E+ ++M+  ++D  D   ++
Sbjct: 145 SISKFFSRLFNVPINDDMFLITEDSIKTYVVQGKEDGAIEEEEQEMIHSIIDFTDTSAKE 204

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           I+ PR+ +  L+ N+ LDE  D II+   SR P+  E  D++ GIL +KDLL F R+  +
Sbjct: 205 ILTPRTSIFALEGNKCLDEVWDSIIDQGFSRIPIYEEQIDNVVGILYSKDLLKFDRTRDK 264

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              + ++ R A  +P +K +  +L+EFR ++ HMAIVIDE+GG  GLVTIED+LE IVGE
Sbjct: 265 DVKVSELKRDAYFIPGTKTLIELLEEFREKQNHMAIVIDEYGGTLGLVTIEDLLEEIVGE 324

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHL 250
           I DEYD E++ +  Q+    + ++    IE  N+    +    +E DTI G V    G +
Sbjct: 325 IRDEYDFEEE-NINQIKDEVFDIKGDTEIETVNKELDINIPISDEYDTIAGYVHYELGKV 383

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHV 279
               + ++ + Y  +V   DS RI +V +
Sbjct: 384 AEVNDKVNGEDYVIRVLHLDSHRIDKVRI 412


>UniRef50_C3X3R1 Magnesium and cobalt efflux protein n=1 Tax=Oxalobacter formigenes
           HOxBLS RepID=C3X3R1_OXAFO
          Length = 324

 Score =  288 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 120/288 (41%), Positives = 173/288 (60%), Gaps = 8/288 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M +   HS +T    + F   L S     EP  R ELL ++ D+ +  LID +   M+EG
Sbjct: 32  MPEHPEHSQNTNKPARTFLDRLAS-FISSEPDTRTELLDILHDAHERKLIDSECLSMIEG 90

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V  + D  VRD+MIPRSQM  +   + + E +  ++E+ HSR+P I  D + I GI+ AK
Sbjct: 91  VFRLFDSAVRDVMIPRSQMYVIDITRPVSEWIGEVMENGHSRYPAIEGDAEKIVGIVHAK 150

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL +     E FS+ ++L  AV +PESKR++ +L++FR+   HMAIV+DEFG +SGLVT
Sbjct: 151 DLLHY---REEGFSVREILHPAVFIPESKRLNVLLRDFRNTHNHMAIVVDEFGNISGLVT 207

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRH----TWTVRALASIEDFNEAFGTHFSDEEV 236
           IED+LE IVG+IEDE+D+++D     L        W + AL  ++DFN   GT  +D  V
Sbjct: 208 IEDVLEQIVGDIEDEFDDDEDDKIVALKAGATGPRWRIPALTEMDDFNRTLGTKLADSRV 267

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           DTIGG V    G +P +G+  DIDG  F+V  AD+R++  + V+    
Sbjct: 268 DTIGGYVANHLGRVPHKGDAFDIDGLHFEVVRADARQLHTLVVEKKPA 315


>UniRef50_B3QS78 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B3QS78_CHLT3
          Length = 460

 Score =  288 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 80/275 (29%), Positives = 142/275 (51%), Gaps = 10/275 (3%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
             L+  +  +      DE+  LI+   Q  + +    DM+  +  ++D+RV  IM PR+ 
Sbjct: 185 LHLIGIKNSNEPDVTEDEIKMLIKQGTQLGVFEAVEHDMVLRIFRLSDRRVSAIMTPRTD 244

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL----LPFMRSDAEAFS 134
           +  +    + DE  + +++  HSRF V   D D+++GI+  KD+         ++ +   
Sbjct: 245 IEWIDLEDSEDEIRNQLMQKTHSRFVVAHGDLDNVDGIIRVKDVAMTGFSTPIANLKVL- 303

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +   LR+ + VPE+  V  +++ F+ +R  MA++IDE G V G+VT+ DILE IVG++  
Sbjct: 304 LKSRLRKPLYVPETLPVFNLMENFKKKREQMALIIDEHGSVQGIVTLNDILESIVGDLPF 363

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFGHLP 251
           E DE ++    +    +W +  +  I++F E F    S EE     T+GG VM   G +P
Sbjct: 364 E-DEPEEQSILEREDGSWLIDGMLPIDEFWEFFNIKSSQEEEWGYQTLGGFVMTKLGRIP 422

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHV-KIPDDS 285
              +T D    +F+V   D +R+ +V V ++P+  
Sbjct: 423 VTSDTFDAHQMRFEVVDMDGKRVDKVLVSRLPNGE 457


>UniRef50_A9KLG3 Putative uncharacterized protein n=1 Tax=Clostridium
           phytofermentans ISDg RepID=A9KLG3_CLOPH
          Length = 487

 Score =  288 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 78/285 (27%), Positives = 158/285 (55%), Gaps = 8/285 (2%)

Query: 14  NKKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           N  G   L   +    E     +E+++++ +  +  +++ +  +M+  +++  ++  +DI
Sbjct: 164 NTNGILRLFGIRPSDLEDNVTEEEIMSMVNEGHEQGVLEAEEAEMISNIIEFNEKAAKDI 223

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL-LPFMRSDAE 131
           M  R +MI +     +++ L  +++  +SRFP+   D D+I G+L  KD+ L F+    +
Sbjct: 224 MTHRKKMIAINSALCIEDALRFMLDENYSRFPLYDGDIDNIVGLLHLKDVMLYFLDPRLK 283

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              + KV R+   +P+++ +D +  + ++++ HMAI IDE+G  +G+V +EDILE IVG+
Sbjct: 284 VEPLSKVAREPYFIPDTQSIDVLFHDMQTKKIHMAIAIDEYGQTAGIVAMEDILEEIVGD 343

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFG 248
           I+DEYD+E+++ + +L   ++ +   AS+ED  +     F++E+    DT+ GL++    
Sbjct: 344 IQDEYDDEEEL-YTRLEDDSYLLSGEASLEDLEDILSLPFAEEDIKNYDTLNGLIVSLLD 402

Query: 249 HLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           H+P   E  TI   GY++++    +R I  V V+   +      D
Sbjct: 403 HIPGDDERATIRYCGYEYELMEIQNRMITSVRVRKIPEEELKASD 447


>UniRef50_B0MHL2 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=B0MHL2_9FIRM
          Length = 443

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 73/259 (28%), Positives = 134/259 (51%), Gaps = 4/259 (1%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           +    +E+  ++    +   ID + ++ +E V +  D    D M   S++  +   Q+ +
Sbjct: 182 QTVTEEEIRLMMELGEEKGTIDSEEKEWIENVFEFGDTTAGDHMTHSSEVTAVSLAQSAE 241

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
           E L++I E+  SRFPV ++  + I GIL A+D L  +  + E  +++++LR A  VPE+ 
Sbjct: 242 EILNIIRETGLSRFPVYAKGFNDIRGILNARDFLMNLNENREK-TLEEMLRPAYFVPETI 300

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
               + ++ + ++ H+A+VIDE+G VSG+VT+ED+LE IVG I DE+D  +     + + 
Sbjct: 301 PSSVLFQDMQKKKIHLAVVIDEYGEVSGIVTMEDLLEEIVGNIYDEFDPSEPPKISKAAE 360

Query: 210 HTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDID--GYQFKV 266
           + W       +    E  G    D  + DT+GGLV      +P  G T +++  G    V
Sbjct: 361 NLWKCSGAVKLNTIAEELGVEIPDHPDYDTLGGLVFSRLHSIPKDGTTFELEICGLHIHV 420

Query: 267 AMADSRRIIQVHVKIPDDS 285
                R+I++  ++   + 
Sbjct: 421 KKMMGRKIVEAEIQKRKNP 439


>UniRef50_C9LMB7 Putative transporter n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LMB7_9FIRM
          Length = 436

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 77/262 (29%), Positives = 139/262 (53%), Gaps = 5/262 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
             DE+  ++ +S +   ++     +++   D  D  VRD+MIPR+ M+ L  N  +D   
Sbjct: 178 TEDEIRCIVEESHRGGRLNTLENTLIKNSFDFFDLDVRDVMIPRNDMVVLDFNDDMDVMR 237

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
             I ++ H+ +PV  EDKDHI G +  KD L  +      +++ +++R+ + VPE     
Sbjct: 238 RNISKTHHTCYPVCMEDKDHILGFIHVKDFLESLLRGE--YNIKRIMREILTVPEVMPAP 295

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+  +++R ++A+V+DE+GG SGLVT+ED++E + GEI    +     +  +++ H +
Sbjct: 296 ALLQMMKNKRTYLAVVVDEYGGTSGLVTLEDLMEELAGEIPQN-ESNAPAEILRVNDHVY 354

Query: 213 TVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
                  +ED +E     F DEE  +TIGGL+      +P  G+ I   G++F V     
Sbjct: 355 EFDGTVILEDVSERLQMEFDDEERNNTIGGLIFSKLERIPQVGDHISFGGWKFTVLKMYG 414

Query: 272 RRIIQVHVKI-PDDSPQPKLDE 292
            RI++V  ++   +  +P   E
Sbjct: 415 FRIMRVKAEMDRKEETEPDSHE 436


>UniRef50_B5Y9X2 CBS domain protein n=1 Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y9X2_COPPD
          Length = 434

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 83/271 (30%), Positives = 146/271 (53%), Gaps = 4/271 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           +  L + +    +ELL ++          ++  +M++ V++ +D  VR+IM PR  +  L
Sbjct: 164 VGSLEYTKVVTDEELLRIVERGRSEGQFLQEEEEMIKSVLEFSDTTVREIMTPRLAVFWL 223

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQA 142
            +N  ++E L ++++S +SR  +     D++ G++  KDL+          S++ + R  
Sbjct: 224 DKNVGVNEALQLMLDSGYSRALLCDGSLDNVLGVIHIKDLMKLHVQGDSEGSLESIKRDV 283

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD-EEDD 201
           + VPE++ ++ +  + R  R H+A+V+DE+G V+G+V++EDILE +VGEI DEYD EE+ 
Sbjct: 284 LFVPETEMINEVFFQMRRLRNHLAVVVDEYGAVAGVVSLEDILEELVGEIRDEYDQEEEP 343

Query: 202 IDFRQLSRH--TWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
           I   + S +     V    S+ D N+        EEVDTI G V+    H P  GE   +
Sbjct: 344 IRIVEKSENYVKAIVLGHVSLGDVNDVLDLDLEAEEVDTIAGFVLLQLQHFPEVGEKFRL 403

Query: 260 DGYQFKVAMADSRRIIQVHVKI-PDDSPQPK 289
           DG +F V    ++RI +V ++    +  QP 
Sbjct: 404 DGTKFTVLSVTNKRIDKVLIEREISEEDQPS 434


>UniRef50_A8DJD8 CBS domain protein n=1 Tax=Candidatus Chloracidobacterium
           thermophilum RepID=A8DJD8_9BACT
          Length = 427

 Score =  287 bits (737), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 77/264 (29%), Positives = 135/264 (51%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
              P   + + ALI    +  +I+ED  ++++ V++ +D  VR+IM  R  +I+++ + T
Sbjct: 163 STPPIEEESIQALIDVGEEAGIIEEDEGELIQSVIEFSDTAVREIMTQRPDIISVRASAT 222

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           + E  + +    HSR PV  +D D I G +  +D+L  +    +   +  ++R A  VPE
Sbjct: 223 VREASETMTRERHSRLPVFEQDSDDIVGFVFIRDVLDCLLHGRDQEPVRNIVRPAYFVPE 282

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           SK +  +L++ R     +A+VIDE+G V+GLVTIEDILE IVGEI+DE     + +    
Sbjct: 283 SKGIADLLEDMRKASVQIALVIDEYGDVAGLVTIEDILEEIVGEIQDEDQPSGEDEVLME 342

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
           +   W V     I           S ++  T+ G ++ A   +P+ GE   + G + +V 
Sbjct: 343 TDGAWLVHGSTEIRKIELVTERELSSDDFQTVNGFIVSALERVPSTGEHFIVRGLEVEVL 402

Query: 268 MADSRRIIQVHVKIPDDSPQPKLD 291
            +D R I +  ++    +  P  +
Sbjct: 403 ESDGRAIRRARLRKAPQTSPPTEE 426


>UniRef50_UPI0001BCCCA8 CBS domain-containing protein n=1 Tax=Aeromicrobium marinum DSM
           15272 RepID=UPI0001BCCCA8
          Length = 438

 Score =  287 bits (737), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 91/270 (33%), Positives = 153/270 (56%), Gaps = 6/270 (2%)

Query: 26  LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRN 85
              G   +  E+  L+  +  + LI+ D   M++ V ++ D  VR++M+PR+ ++ ++++
Sbjct: 161 FSEGPFASEVEVRELVDLAAASSLIESDESKMIQSVFELGDTIVREVMVPRTDIVFIEQH 220

Query: 86  QTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD---AEAFSMDKVLRQA 142
           +TL + + + + S +SR PV+ ++ D + G+   KD+   +  +     A  +  +LR  
Sbjct: 221 KTLRQSMSLALRSGYSRLPVVEDNLDDVVGMAYLKDVTKRVFDNHTAEHAERVSSILRPC 280

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
           + VP++K  D +LKE ++QR H+AIV+DEFGG +G+VTIEDILE IVGEI DEYD E D 
Sbjct: 281 LFVPDTKHADELLKEMQAQRTHVAIVVDEFGGTAGMVTIEDILEEIVGEITDEYDTEPD- 339

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGY 262
           +   L   +W V +   ++D  E  G    DE+VD++GGL+ +  G +P  G  I I+G 
Sbjct: 340 ELEVLVDGSWRVSSRYDVDDLAELTGVDLQDEDVDSVGGLLAKHLGKVPIPGSAIVIEGL 399

Query: 263 QFKVAMADSR--RIIQVHVKIPDDSPQPKL 290
           +        R  RI +V V    +   P+ 
Sbjct: 400 RLVAEAPSGRRNRIGRVLVTRLTEDDDPES 429


>UniRef50_A3EP54 Putative uncharacterized protein n=2 Tax=Leptospirillum sp. Group
           II RepID=A3EP54_9BACT
          Length = 455

 Score =  287 bits (736), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 76/283 (26%), Positives = 143/283 (50%), Gaps = 8/283 (2%)

Query: 13  SNKKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +  +G   +L  +      P + +EL  L+++  +  +I+   +D+++ V    D  VR+
Sbjct: 162 ATSQGLLRMLGVRNSRSAYPISPEELDLLLKEGTEQGVINRTEQDLIQSVFKFTDISVRE 221

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M+PR +M+ +  + T+++  + + +   SR+PV+      + GIL  KDL        +
Sbjct: 222 VMVPRMKMVVMDASMTIEQATNFLSDHRFSRYPVVRTGTGEVVGILYYKDLFENYVRSRQ 281

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  ++     +PES +V   LKE + +R  MA+V+ E+G + GLVT+ED+LE +VGE
Sbjct: 282 G-RLTDLVHAPFFIPESMKVAHTLKEMQKRRTQMALVLSEYGTLEGLVTMEDLLEELVGE 340

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHL 250
           IEDE D+       +L   ++ V A  SI D  E +     + ++ +T+ G V+     +
Sbjct: 341 IEDESDDIQKP-VERLRDGSYLVDASQSIRDLREDYHLDIPEGDDYETLAGFVVAQLQTI 399

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKI----PDDSPQPK 289
           P  GE   ++  +  +   D  R+ +V ++     PD  P P 
Sbjct: 400 PRGGEFFYMNHLKVTIVDMDKYRVSRVKIEPVPDMPDLPPAPA 442


>UniRef50_B6JNY8 Hemolysin domain-containing protein n=23 Tax=Campylobacterales
           RepID=B6JNY8_HELP2
          Length = 445

 Score =  287 bits (736), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 76/252 (30%), Positives = 140/252 (55%), Gaps = 2/252 (0%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H    + +EL  ++ +S +  +ID    ++++  +D +D   ++IM PR  M+ L    +
Sbjct: 188 HDGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVCLDEENS 247

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
            +E +D++++S  +R+P     KD+I G++  +DLL       +    ++++R+ ++VPE
Sbjct: 248 YEENIDIVLKSRFTRYPYCKGSKDNIIGMVHIRDLLSRSIFTPKMHDFNQIVRKMIIVPE 307

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           S  + ++L + + ++ H A+VIDE+GG +GL+T+EDI+E I+GEI DEYD + +    +L
Sbjct: 308 SASISQILIKMKKEQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQE-GVNKL 366

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
               + +  +  +E   E     F  E E  T+GG V      +P  G+TI   GY F+V
Sbjct: 367 EEGVFELEGMLDLESVEEVLHIEFDKECEQVTLGGYVFSLLERMPMEGDTIVSHGYSFEV 426

Query: 267 AMADSRRIIQVH 278
              D  RI ++ 
Sbjct: 427 LSVDGARIKRLK 438


>UniRef50_D1VUR6 CBS/transporter domain protein n=1 Tax=Peptoniphilus lacrimalis
           315-B RepID=D1VUR6_9FIRM
          Length = 439

 Score =  287 bits (735), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 88/261 (33%), Positives = 152/261 (58%), Gaps = 6/261 (2%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  + +EL + I+ S +  +I+    DM+  +MD  D+   +IM PR+ +  +  ++   
Sbjct: 179 EQISEEELKSYIKVSQEQGVINSTGEDMIINIMDFDDKMAYEIMTPRTAIFMVDYDEFSV 238

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAFSMDKVLRQAVVVPES 148
           + +  I+ + +SR PV  E+ D+I GI+  KDL   + +++ + F++DK L+    VPE+
Sbjct: 239 DSISEILATGYSRMPVYRENADNIIGIINIKDLFIEYEKNNYKNFNLDKCLKTPYFVPET 298

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K++DR+LKE ++ + ++AI+IDE+GG SG+VT+EDI+E IVGEIEDEYD        ++ 
Sbjct: 299 KKIDRLLKELQTSKNYVAILIDEYGGFSGMVTVEDIVEEIVGEIEDEYDRNTPS-MEKIG 357

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET----IDIDGYQF 264
            + + V    +IED NE   T    E  +TI GL+++  G++P   E     +  +G   
Sbjct: 358 PNEYMVDGYMTIEDINEELDTKLFSENHETISGLIIEKLGYIPEENEKKKLQVKTNGVML 417

Query: 265 KVAMADSRRIIQVHVKIPDDS 285
            V     +RI++  +KI D+ 
Sbjct: 418 TVLAIKDKRIVKAALKILDNK 438


>UniRef50_C8XF87 CBS domain containing protein n=11 Tax=Bacteria RepID=C8XF87_NAKMY
          Length = 537

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 98/270 (36%), Positives = 151/270 (55%), Gaps = 8/270 (2%)

Query: 24  SQLFHGEPKNRD-ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
            + F   P + D EL  L+  +G   +++E  R+ML+ V D+ D  VR++M+PR++ + +
Sbjct: 152 GRGFREGPFSSDIELRELVDIAGSRGVVEETEREMLQSVFDLGDTIVREVMVPRTETVWI 211

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP---FMRSDAEAFSMDKVL 139
           +R++TL + L +   S  SR PV+ ED D I G+   KDL+     +  D +   + +++
Sbjct: 212 ERDKTLRQALALASRSGMSRIPVVGEDLDDIVGVAYLKDLIAPAMNLAPDDQGPVLTQIM 271

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
           R+ V VPESK VD +L+E +  R H A+V+DE+GG +G+VTIEDILE IVGEI DEYD +
Sbjct: 272 REPVFVPESKNVDDLLREMQRDRTHFAVVVDEYGGTAGIVTIEDILEEIVGEITDEYDAD 331

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
                  L   ++ V A   +ED  E F     D+EVDT+GGL+ Q  G +P  G  + +
Sbjct: 332 TPAPVVPLPDGSFRVSARLPVEDLGELFDVELDDDEVDTVGGLLAQQLGRVPLPGSEVGV 391

Query: 260 DGYQFK----VAMADSRRIIQVHVKIPDDS 285
            G        V      R+  V V+    +
Sbjct: 392 AGLFLHGEPGVDRRGRPRVQTVLVRRLTAA 421


>UniRef50_C6QET7 Putative uncharacterized protein n=1 Tax=Hyphomicrobium
           denitrificans ATCC 51888 RepID=C6QET7_9RHIZ
          Length = 441

 Score =  286 bits (734), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 76/250 (30%), Positives = 129/250 (51%), Gaps = 4/250 (1%)

Query: 34  RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLD 93
            +E+   I    +   + +   +ML G++D+ D +V DIM+ R++M T+  +    + LD
Sbjct: 168 HEEIRGTIDLQAKEGTVAKGDAEMLGGILDLGDLQVADIMVHRTKMETVNADDPPAKILD 227

Query: 94  VIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLR---QAVVVPESKR 150
            +++S  +R P+  E+ ++I G+L  KDLL  +     A     +++       VP++  
Sbjct: 228 QLMKSQFTRVPIWKEEPENIVGVLHTKDLLLALSRTGWAPETLDIMKSASTPWFVPDTTT 287

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH 210
           +   L +F  ++  MA+V+DE+G V GL+T+EDILE IVG+I DE+D   D   R  S  
Sbjct: 288 LKDQLNQFLKKKTQMALVVDEYGEVQGLITLEDILEEIVGQITDEHD-NPDSHIRMQSDG 346

Query: 211 TWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
           T  V    +I D N        D+E  TI GLV+     +P  G+     GY+F++    
Sbjct: 347 TVNVDGTVAIRDLNRHLDWDLPDDEATTIAGLVIHEAQTIPEPGQVFTFHGYRFEILRKS 406

Query: 271 SRRIIQVHVK 280
             +I  + +K
Sbjct: 407 RNKITAIRIK 416


>UniRef50_B8GI66 Putative uncharacterized protein n=1 Tax=Methanosphaerula palustris
           E1-9c RepID=B8GI66_METPE
          Length = 435

 Score =  286 bits (734), Expect = 5e-76,   Method: Composition-based stats.
 Identities = 82/273 (30%), Positives = 133/273 (48%), Gaps = 6/273 (2%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
            ++L ++   G P   +E+  LIR+  Q  +  E+ + M+  ++ ++D+RV  +M PR +
Sbjct: 165 LAMLGAKNSSGSPVTEEEVKLLIREGTQAGVFLEEEQAMVSRILRLSDRRVSGLMTPRPE 224

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           +  +       E + ++  S HS FPVI  D D I G++  +DL   M    EA ++   
Sbjct: 225 ITAIDLRSPDLEQIALMRASGHSYFPVIDGDLDRIRGMVSVRDLWARMLDGQEA-TVRGA 283

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           L + + +PES    ++   FR    H+ +V DE+G V GLVT  DILE IVG +    D+
Sbjct: 284 LSEPLYIPESVPALKVPALFRDAGLHLGLVTDEYGSVQGLVTPHDILESIVGVLPS-PDQ 342

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEE---VDTIGGLVMQAFGHLPARG 254
           E + +  Q    +W V  +  ++ F +         EE     TIGGLVM      P  G
Sbjct: 343 EAEPEIVQRDDGSWLVDGMLPLDQFRDVVPLEDLPLEEKGYYHTIGGLVMMHLERRPQTG 402

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           +       QF+V   D  R+ +V V   D++ Q
Sbjct: 403 DRFTHGDLQFEVVDMDGNRVDKVLVTQVDEADQ 435


>UniRef50_A9VF50 Putative uncharacterized protein n=6 Tax=Bacillus
           RepID=A9VF50_BACWK
          Length = 437

 Score =  286 bits (733), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 78/255 (30%), Positives = 145/255 (56%), Gaps = 3/255 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H      +EL  ++ +S +   I++     +  + +  ++  ++IM+PR+++I L  + +
Sbjct: 175 HDVAHTEEELRLILSESYERGEINQAEYKYVNNIFEFDNRIAKEIMVPRTEIIGLHVDNS 234

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAF-SMDKVLRQAVVV 145
           L + + +I +  ++R+PV  EDKD I G++  KD    +M  + + F S+    R  + V
Sbjct: 235 LADHMKIIRDEKYTRYPVFGEDKDEIIGMVNVKDFFIRYMNKETKEFNSIQSYTRPVIEV 294

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFR 205
            E+  +  +L + + +R  +A++ DE+GG +G+VTIEDILE IVGEI DEYDE++    +
Sbjct: 295 IETIPIHNLLLQMQKKRIPLAVLYDEYGGTAGIVTIEDILEEIVGEIRDEYDEDERPPIQ 354

Query: 206 QLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
           Q++     V     I + N+  G H +D +VDTIGG ++     +   G+T++ +GY FK
Sbjct: 355 QMNEGHLVVEGKVLISELNDLLGLHMNDSDVDTIGGWILMQNYDI-QEGQTVNSEGYAFK 413

Query: 266 VAMADSRRIIQVHVK 280
           +   D  +I +V ++
Sbjct: 414 ILSKDPHQIKRVEIQ 428


>UniRef50_A2SJR8 CBS domain protein n=8 Tax=Burkholderiales RepID=A2SJR8_METPP
          Length = 439

 Score =  286 bits (733), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 69/272 (25%), Positives = 126/272 (46%), Gaps = 7/272 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      LL  +         +E+ A + +     +I+     M+  V  + ++++  +M
Sbjct: 157 STGAILGLLGIRDTQSRGVTEEEIAASLEEGFDAGVIEAQEHQMVRNVFRLDERQIGSMM 216

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR ++  L     + + L VI    HSR+PV     D + G++  + LL  + S  +  
Sbjct: 217 IPRGEIAWLDSTTPIADALAVIAAHEHSRYPVCRGGLDEVLGVVGTQHLLQQVTSG-KPL 275

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           S+ + L+  V VPE+     +L++FR     M  V+DE+G V G++T+ D+LE I GE  
Sbjct: 276 SLTEGLQPPVFVPETLTGMELLEQFRGSTTQMVFVVDEYGEVQGVITLRDVLEAITGEFT 335

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEE---VDTIGGLVMQAFGH 249
                 DD    Q    +W +  L  + +  +  G     DE+    +T+ G+ M   G 
Sbjct: 336 --TPTADDAWAVQRDDGSWLIDGLIPVPELKDRLGLKELPDEDRGRYNTLAGMTMLLLGR 393

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           LP   + ++  G++F+V   D +R+ +V V  
Sbjct: 394 LPQTADVVEWAGWRFEVVDLDGKRVDKVLVNR 425


>UniRef50_C2ECT1 Hemolysin n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2ECT1_9LACO
          Length = 453

 Score =  286 bits (733), Expect = 7e-76,   Method: Composition-based stats.
 Identities = 89/285 (31%), Positives = 152/285 (53%), Gaps = 9/285 (3%)

Query: 8   SSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           ++ ++ NK       ++        +  ++L +I +   N  +D +  +M++GV+ + D+
Sbjct: 150 TAVSLINKHFVIKRDVTDTAEDPTASWQDILDMIEEGRNNGELDTNEYEMIDGVISMHDK 209

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
             R+IM+PR+    +         +D I+    SR PV  EDKD++ GI+  K L+   R
Sbjct: 210 MAREIMVPRTDAFMVDVTNDNSRNIDSILGMDFSRVPVYHEDKDNVVGIVHIKTLVKLAR 269

Query: 128 S-DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
           +   +  ++ + +R A  VPE+  +D +L + +  R  MAI++DE+GGV GLVT+ED+LE
Sbjct: 270 NFGFDHITIRQAMRPAFFVPETMTLDELLFQMQKTRNQMAILLDEYGGVVGLVTLEDLLE 329

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            IVGEI+DE DE D + ++Q+S   + V+    I+DFN+ FGT     ++DTI G ++  
Sbjct: 330 EIVGEIDDESDEPDQL-YQQISSDEFLVQGKMPIDDFNDEFGTDLKINDIDTIAGFLIAK 388

Query: 247 FGHLPARGETIDI------DGYQFKVAM-ADSRRIIQVHVKIPDD 284
            G +P   E + +             A   D  RI +V V +PD 
Sbjct: 389 LGRIPDNDEVVSVTTESSEGDVVLTTAKIIDDARITEVKVTLPDA 433


>UniRef50_Q2FN37 Putative uncharacterized protein n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FN37_METHJ
          Length = 437

 Score =  286 bits (733), Expect = 7e-76,   Method: Composition-based stats.
 Identities = 71/280 (25%), Positives = 145/280 (51%), Gaps = 13/280 (4%)

Query: 19  FSLLLSQLFHGEPKN-----RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
            + ++ +LF   P        +E+  L+ +  ++ +IDE  +DM+E V +  D ++ D+M
Sbjct: 160 LTNIIVKLFGISPVTSPDVIEEEIHMLLEEGTESGIIDETEQDMVESVFEFGDSQIADLM 219

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR  ++ L  N  + +  ++I  + H+R+P+  +  D I GI+  +DL      + E  
Sbjct: 220 IPRPDIVALNLNDPITKNFEIIERTGHTRYPIYQDTLDSIIGIISIRDLWLIAHKNTE-V 278

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
              K+++  +VVP++ +   +++ F++    +A++IDE+G V GL+T+ D+LE +VG++ 
Sbjct: 279 DFSKIMQDILVVPDNMKALDLIRRFKTATSPLAVIIDEYGSVVGLITLHDLLEALVGDLS 338

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE----VDTIGGLVMQAFGH 249
               ++++    +    +W +    S E+  E  G   S+E       T+ G ++   G 
Sbjct: 339 RVDQDDEEPLITRRHDGSWLIDGRTSPEELYEITGIDCSEESSKGAFRTMAGFILYKMGS 398

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           +PA G+    DG +++V   D  RI ++ +      P P+
Sbjct: 399 IPATGDYFSYDGNEYEVVDMDGHRIDKILITR---LPSPE 435


>UniRef50_C7NDD7 CBS domain containing protein n=3 Tax=Leptotrichia
           RepID=C7NDD7_LEPBD
          Length = 427

 Score =  286 bits (732), Expect = 8e-76,   Method: Composition-based stats.
 Identities = 75/258 (29%), Positives = 141/258 (54%), Gaps = 2/258 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              DE+L  ++   ++ + +E   +M+  + + ++  V++I+ PR  +  L+    +D+ 
Sbjct: 171 ITEDEILTFLKAGTESGVFEEGEEEMITSIFEFSETTVKEILTPRRDVFALEAESKIDDV 230

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
            + I++   +R P+ +E  D I G +  KDLL + +   E   +   +++A  VP +K +
Sbjct: 231 WNEILDQGFTRIPIYTETIDKIVGTVHMKDLLRYDKQTGENPPIKDFMKEAYFVPITKPL 290

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
             +L+EF+ ++ HMAIVIDE+GG  G+VTIED+LE IVGEI DE+D+E++ + +Q+    
Sbjct: 291 VELLEEFKLKQLHMAIVIDEYGGTQGIVTIEDLLEEIVGEIRDEFDQEEE-NIQQIREKI 349

Query: 212 WTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
           + ++    IE+ N+         EE DTI G +    G +    + +  D +  KV   D
Sbjct: 350 FDIKGDTPIEEINDKLEIEIPLSEEYDTISGYIQDKLGKVADVFDQVKGDNFVLKVTDVD 409

Query: 271 SRRIIQVHVKIPDDSPQP 288
           ++R+ +V   I +   + 
Sbjct: 410 NKRVERVRAVIIEQEKEE 427


>UniRef50_C9KMQ2 CBS domain protein n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KMQ2_9FIRM
          Length = 445

 Score =  286 bits (732), Expect = 9e-76,   Method: Composition-based stats.
 Identities = 99/283 (34%), Positives = 157/283 (55%), Gaps = 6/283 (2%)

Query: 6   SHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIA 65
           +H ++ ++++ GF +       H      +E+  L+ +S +  LID+   D ++ V D  
Sbjct: 161 NHVANWVAHRMGFHTASEGDDAH----TEEEIRLLMEESHRQGLIDDTEVDFVDNVFDFT 216

Query: 66  DQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF 125
           D  VR+IM PR+ M+ L    T++E L  I+E   +R+P+  EDKDHI G L  KDL+  
Sbjct: 217 DLNVREIMTPRTDMVCLYLEDTMEENLHTILEEQLTRYPICHEDKDHIVGFLHVKDLMRI 276

Query: 126 MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDIL 185
           M    +  ++ ++ R+A++VPES  V  +LK  + QR  MAIV+DE+GG +G+VTIEDI+
Sbjct: 277 MAEGRKP-NLRRLARKALIVPESMDVSVLLKTMQKQRSQMAIVVDEYGGTAGMVTIEDIV 335

Query: 186 ELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQ 245
           E IVG+I+DE+DEE      +  +  ++V A   +E+  +       DE+VDTIGG +  
Sbjct: 336 EEIVGDIQDEFDEERPTA-ERRGKRIFSVDAKMLLEELEDILEIDIEDEDVDTIGGWLYD 394

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
             G  P  G+     G  F V   D  RI +V +   +D  + 
Sbjct: 395 QIGQTPRVGQMAASGGNLFYVEEVDGVRITRVLIHCAEDLEKE 437


>UniRef50_C4V614 TlyC family hemolysin n=14 Tax=cellular organisms
           RepID=C4V614_9FIRM
          Length = 447

 Score =  286 bits (732), Expect = 9e-76,   Method: Composition-based stats.
 Identities = 85/254 (33%), Positives = 141/254 (55%), Gaps = 2/254 (0%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           + +    +E+  L+++S +  LI+    D ++ V    +   R+IM+PR+ MI L  + +
Sbjct: 179 NEDAHTEEEIRLLMKESYRQGLINSTEADFVDKVFSFTELNAREIMVPRTDMICLYLDDS 238

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
             E +  I+E   +R+PV  EDKDHI G +  KDLL  +    E  ++ + +R+A++VPE
Sbjct: 239 PAERIKTILEEQQTRYPVCYEDKDHIIGFIHVKDLLAPLMRG-EQLNLRRYIRKALIVPE 297

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           S     +L+  + Q Y +AIV+DE+GG +G+VT+EDI+E IVG+I DE+D E +      
Sbjct: 298 SMDGSILLRTMQEQGYQLAIVVDEYGGTAGMVTVEDIIEQIVGDIRDEFDVERES-VEWR 356

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
                ++ A   +E+ N+  G    DE+VD+IGG +    G  P  G+    +G    V 
Sbjct: 357 DLDICSIDAKLLLEEVNDLLGIRIEDEDVDSIGGWLYDQLGEAPRVGQMAAHEGALLYVE 416

Query: 268 MADSRRIIQVHVKI 281
             D  RI +V V++
Sbjct: 417 EVDGIRITRVLVRL 430


>UniRef50_A0LG68 CBS domain containing protein n=1 Tax=Syntrophobacter fumaroxidans
           MPOB RepID=A0LG68_SYNFM
          Length = 276

 Score =  286 bits (732), Expect = 9e-76,   Method: Composition-based stats.
 Identities = 80/265 (30%), Positives = 144/265 (54%), Gaps = 4/265 (1%)

Query: 21  LLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI 80
             LS++   E     E+  LI +  Q  LI ED  +M++G+    D   R+IM+PR+  +
Sbjct: 4   RRLSRIGSSENI-EKEIQQLIDEGEQAGLISEDEGEMIQGIFSFRDTIAREIMVPRTDAV 62

Query: 81  TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLR 140
             +   T  + + +II+S HSR P+  +  D+I G L AKDLL +    ++   +  ++R
Sbjct: 63  YARAETTTADVIQLIIQSGHSRIPIYQDSIDNIIGTLHAKDLLKYW--GSDDVDLRAIIR 120

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
               +PESK++  +L++ R  + HMAIV+DE+GG +G++T+EDI+E I+G++ DEYD  D
Sbjct: 121 SPYFIPESKKISEVLEDLRDNKSHMAIVVDEYGGTAGILTLEDIIEEIIGDVMDEYD-AD 179

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
                +    + TV A   +E+  +       + + +++GG V+   G +P   E I  +
Sbjct: 180 VKLIVEHDDGSITVHARLDVEELEDFLDVKLPEGKFESVGGFVISLVGRVPGVNERIVFE 239

Query: 261 GYQFKVAMADSRRIIQVHVKIPDDS 285
             +  +  A +R+I ++ ++  D  
Sbjct: 240 NMEMVIEAASNRKIEKIRIRRVDPE 264


>UniRef50_C2MBP5 Gliding motility-associated protein GldE n=1 Tax=Porphyromonas
           uenonis 60-3 RepID=C2MBP5_9PORP
          Length = 452

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 95/278 (34%), Positives = 150/278 (53%), Gaps = 11/278 (3%)

Query: 20  SLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQM 79
            LL S+   G   + D+L   +  +      D    +M+  ++    +   +IM+PR  M
Sbjct: 173 KLLGSKARRGPELSVDDLSEAVALTTNG---DNKETEMIHEIVKFYHKTADEIMVPRVDM 229

Query: 80  ITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVL 139
           I +  +    + L   +++ +SR PV    +D I G+L  KDLLP M  + + F   K++
Sbjct: 230 IGVNYHWAYHQTLSFAVDTGYSRLPVYDGSQDSIRGVLYVKDLLPHMHEE-DTFPWQKII 288

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
           RQA  VPE+K++D +L+E + +R HMAIVIDEFGG SGL+T+EDILE IVGEI DEYD+E
Sbjct: 289 RQAYFVPENKKIDTLLEELQQERIHMAIVIDEFGGTSGLITLEDILEEIVGEIVDEYDDE 348

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-----DEEVDTIGGLVMQAFGHLPARG 254
           D   + +L+   + +    S+ D  +             EEVDT+GGL ++    +P  G
Sbjct: 349 DPP-YVRLAEGVYLIDGGMSLIDLCKLLDVEPEYFAPHYEEVDTVGGLFLEVLQEIPQVG 407

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKI-PDDSPQPKLD 291
           + I I    F V   +  RI+Q+ +++ P +    + D
Sbjct: 408 QQITISDIDFIVTRMERHRIMQLKMRLHPKEQTDTQTD 445


>UniRef50_C0CHP0 Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica
           DSM 10507 RepID=C0CHP0_9FIRM
          Length = 460

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 77/292 (26%), Positives = 160/292 (54%), Gaps = 9/292 (3%)

Query: 9   SDTISNKKGFFSLLLSQLFHGEP--KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           +  IS      + LL             +E+++++ ++ +  +I+E   +M++ ++  ++
Sbjct: 168 TSLISGISAGLTRLLGLDAKKVQGDVTEEEIISMVGEAHEQGVIEESEAEMIQNLISFSE 227

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
           +  +DIM PR  +  L    TL++ +++++E  +SR+PV  ED D+I G+L  +D++P +
Sbjct: 228 KEAKDIMTPRMNITALDAQMTLNDAIEIMLEEGYSRYPVYVEDLDNILGVLNFRDVVPII 287

Query: 127 -----RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
                  +     +  ++R  V +PE++ ++++L+  ++++ HM +V+DE+G   GLV +
Sbjct: 288 TKSERAGERPLRELPGLIRSVVFIPETRGINQILQGMQARKTHMVVVVDEYGQTEGLVAM 347

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGG 241
           EDILE IVGEI DEYDEE+  + +     +  +     +E+  E  G  F D+E++T+ G
Sbjct: 348 EDILEEIVGEIHDEYDEEE-ANIQPQLDQSVIIDGFTRLEELEEELGMEFGDQEMETLNG 406

Query: 242 LVMQAFGHLPARGE-TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            +     H+P   +  +  +GY+F++   ++  I +V  +    + Q  L+E
Sbjct: 407 YLTYMLDHIPTIKDKEVIANGYRFEILSVENNTIQKVKARKLPSAAQTPLEE 458


>UniRef50_A9F240 Conserved hypothetical membrane protein n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9F240_SORC5
          Length = 430

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 86/253 (33%), Positives = 147/253 (58%), Gaps = 4/253 (1%)

Query: 34  RDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLD 93
             E+  L+ +  ++ L   +  +M+  V++ AD   RD+M+PRS++  ++ +  L++ L+
Sbjct: 169 EAEVEILVDEVERSGLFGREPAEMIRNVLEFADLTARDVMVPRSKVEAIEISTPLEKVLE 228

Query: 94  VIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAFSMDKVLR-QAVVVPESKRV 151
           ++ ES HSR+PV  +  D+I G+L AKDL   +     +  ++ ++ R  A  V ES+ +
Sbjct: 229 IVTESGHSRYPVYKDQTDNIAGLLYAKDLFKVLEERRLKNTTLREITRSPANFVAESQPL 288

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD-IDFRQLSRH 210
             +L+E +S+R H+AIV+DEFGG+SG+VT+ED+LE IVG+I DE+DE DD    + L   
Sbjct: 289 SSLLREMKSRRQHLAIVVDEFGGMSGIVTLEDVLEEIVGDIRDEHDETDDGAAIQDLGDG 348

Query: 211 TWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
                A  S+ D +   G     + + D++GG++ Q  G +P  G  +   G +F V  +
Sbjct: 349 RLVADAAVSMSDLSAYLGAELDREGKYDSLGGMLTQHVGKVPEVGTAVSKFGLRFIVRDS 408

Query: 270 DSRRIIQVHVKIP 282
           D R I +V +  P
Sbjct: 409 DERHIGKVEIVRP 421


>UniRef50_Q7NMI1 Glr0785 protein n=2 Tax=Bacteria RepID=Q7NMI1_GLOVI
          Length = 477

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 79/274 (28%), Positives = 139/274 (50%), Gaps = 13/274 (4%)

Query: 17  GFFSLLLSQLF--------HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
            + S L+ + F        H  P   +EL  LI  S  +  +D+  +++LE V +  D  
Sbjct: 180 NWSSWLVLRAFGVKANVNTHTNPIGPEELQLLISSSSASG-LDKGEQELLENVFEFGDAV 238

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS 128
             D+M+PR+ +  L    T+ E L  +  + HSR+P+  +  D I+G +  KD++  +  
Sbjct: 239 AIDVMVPRTSIDALPFTATIQEVLFEVSRTGHSRYPLYEDSLDTIKGQVSIKDVITPLAK 298

Query: 129 DA--EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
                  ++  + R  + VPE+KR+  +L + + +R  M IV+DEFGG +GL+T+E++LE
Sbjct: 299 GEVQPTDTVGGLARPILFVPENKRISELLTQMQRERQAMVIVVDEFGGTAGLLTMENLLE 358

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQ 245
            +VG I DE D+    D  +L   T  ++A  ++E+ N+         +E  T+GG VM 
Sbjct: 359 ELVGNITDESDQATP-DIVKLDERTAIIQAQINLEELNDFLDLQLPISDEYKTLGGFVMY 417

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
               +P  GE    +  +F V   +  R+ +V +
Sbjct: 418 QLHKVPEAGEQFFYNELEFTVLEMEGPRLERVRL 451


>UniRef50_Q3ZYX1 Probable hemolysin-related protein n=5 Tax=Dehalococcoides
           RepID=Q3ZYX1_DEHSC
          Length = 424

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 76/271 (28%), Positives = 148/271 (54%), Gaps = 8/271 (2%)

Query: 17  GFFSLLLSQLFHGEP-----KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           G+ S   ++LF G          D++ A+I    +   ++ED  ++L  V + +D+ VR+
Sbjct: 146 GWISSGFTKLFGGPSLKSSLVAEDDIRAMITVGHKEGTVEEDKAELLHKVFEFSDRPVRE 205

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +++PR ++ ++++  TL + LD+  ES  SRFPV  E+ D++ GIL  KD+L  +     
Sbjct: 206 VIVPRPEVESVEKGSTLKDFLDLYAESPMSRFPVYEENMDNVLGILSIKDVLMALAKGTH 265

Query: 132 AF--SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
               S+D ++R A   PE+K + ++  E R + + M +VIDE+GG +G+V++  ++E IV
Sbjct: 266 TPQDSVDDLMRPAYFAPETKPIGKLFNEMREKNFRMCVVIDEYGGTAGIVSLSRLMEEIV 325

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G + DE  + +  D+  ++ +T+ V     IE+ N        + + +TI GL++   G+
Sbjct: 326 GPVGDELADAEK-DYESINEYTFQVDGSMRIEEANVEMDLDLPEGDYETIAGLILDRLGY 384

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
           +P +G+ I +   +  +      +I +V + 
Sbjct: 385 IPKQGQQIKLQNLKVVITHMKGMKIDEVLIT 415


>UniRef50_A2SSZ1 Putative uncharacterized protein n=1 Tax=Methanocorpusculum
           labreanum Z RepID=A2SSZ1_METLZ
          Length = 420

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 93/289 (32%), Positives = 146/289 (50%), Gaps = 18/289 (6%)

Query: 18  FFSLLLSQLF----------HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           F ++LLS LF          H      +E+   I        I+E+ ++M+  V+   D 
Sbjct: 130 FLTMLLSPLFYVYDRFRKKDHSPSVTEEEIREWIDVGEMEGAIEEEEKEMIYSVLKFNDT 189

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
             ++IM PR  +  ++   TL+E +    E+  SR PV  +  D+I G L  KDL     
Sbjct: 190 TAKEIMTPRPDVAVVEDTVTLEEAVSHFRETGFSRVPVYHDKTDNIVGTLNFKDLFNAYS 249

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
           +D    S+  ++     VPESK++D +L+E + +R HMAIV+DEFGG SG+VT EDILE 
Sbjct: 250 TDNRKASVKSLMLDVYCVPESKKIDVLLRELQVRRVHMAIVLDEFGGFSGVVTFEDILEE 309

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE--VDTIGGLVMQ 245
           +VG+I DE D ++  D   +    + + A   +   NE F     ++    +TIGGLV  
Sbjct: 310 LVGDIMDESDGDEVSDIIPIGDGLYMIDAQVRVALLNERFDISLPEDPGNYETIGGLVFS 369

Query: 246 AFGHLPARGETIDIDG--YQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
             GH+P  GE+I + G      V     R+I++V + +      P+ D+
Sbjct: 370 QLGHIPRLGESIPLPGDHITLVVTKMRGRQILKVKMIL----AAPEYDD 414


>UniRef50_Q30WW6 CBS n=5 Tax=Proteobacteria RepID=Q30WW6_DESDG
          Length = 442

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 76/283 (26%), Positives = 135/283 (47%), Gaps = 8/283 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      L+            +++ A++ +  Q  +I++   DM+  V  + D+++  +M
Sbjct: 156 STDALLRLVGKTELSSANLTEEDIHAILTEGSQAGVIEKHEHDMVRNVFRLDDRQIPSLM 215

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PRS ++ L   Q LD  LD ++ S HSRFPV       + G++ AK LL     +  A 
Sbjct: 216 TPRSDIVFLDITQPLDGFLDTVVASDHSRFPVCRGGLHEVLGVISAKRLLKQRLKNEPAE 275

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            +   L  AV VPES    ++L++FR     M  V+DE+G +SGL+T++D+LE + G+  
Sbjct: 276 KLTGYLLPAVYVPESLTGMKLLEQFRESGVQMVFVVDEYGDISGLITLQDLLEALTGKFR 335

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE----VDTIGGLVMQAFGH 249
               + D++   Q    +W +  L  + +  +        +E      T+ G++M  FG 
Sbjct: 336 --PRDPDEMWAVQRDDGSWLLDGLIPVPELKDRLDLKTVPDEAKVRYHTLSGMMMWLFGR 393

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD--DSPQPKL 290
           LP  G+  +  G+Q +V   D +RI +V        ++ QP  
Sbjct: 394 LPRTGDVAEWQGWQLEVVDLDGKRIDKVLASRISGYEASQPSA 436


>UniRef50_Q1IKR7 Putative uncharacterized protein n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IKR7_ACIBL
          Length = 455

 Score =  285 bits (730), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 84/289 (29%), Positives = 150/289 (51%), Gaps = 22/289 (7%)

Query: 20  SLLLSQLFH------GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +  + +LF       G   + +EL  ++  S +  L+     +M+   +D+ +  VR+IM
Sbjct: 163 ARFVLRLFGTKEMREGGVHSPEELKLMVTASRKFGLVPRLQEEMINRAIDLENISVREIM 222

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVI--SEDKDHIEGILMAKDLLPFMRSD-- 129
           +PR  + +L  + TLDE +  +++  HSR P+       +HI G+L AKDL+ +MR    
Sbjct: 223 VPRPDIFSLPGHMTLDEAVQRVVDEQHSRIPIYDAERGPEHIIGVLYAKDLMRWMRYRIA 282

Query: 130 ----------AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
                     A    +  ++R+ +VVPE+K +  +L+EF+ ++ H+A+V+DEFG  +G+V
Sbjct: 283 RLQQNRPARIASNLKVQHIMREVLVVPETKPLTDLLEEFKERKRHLAVVVDEFGSTAGVV 342

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDT 238
           T+ED+LE +VGEIEDE+D  ++         T  +    +I D    +      DE  +T
Sbjct: 343 TVEDVLEELVGEIEDEHDVPEESALTP-GGTTLVLDGGINIRDLESQYQVRLPRDEGFET 401

Query: 239 IGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           + G VM     +P  G++     Y+F V   + RRI  V +++   + +
Sbjct: 402 LAGFVMTRLQRIPREGDSFAFHNYRFTVLEMEGRRIDSVKLELIQQAEE 450


>UniRef50_Q67QV0 Putative hemolysin n=1 Tax=Symbiobacterium thermophilum
           RepID=Q67QV0_SYMTH
          Length = 452

 Score =  284 bits (727), Expect = 3e-75,   Method: Composition-based stats.
 Identities = 78/282 (27%), Positives = 133/282 (47%), Gaps = 12/282 (4%)

Query: 13  SNKKGFFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           ++      LL  Q    EP  + +EL   +    +N  + E  + M+ GV    D+ VR 
Sbjct: 159 ASTNLVVRLLGGQAQPAEPGISEEELRLYV---AENTGLQEAEKRMIAGVFSFGDRSVRQ 215

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M+PR++M  L ++  L E L  +      R+PV  ED D I G++  KDLL      A 
Sbjct: 216 VMVPRTEMACLHQDAPLPEALAEVRRHGFWRYPVYREDYDDIVGMVTVKDLLRHADPQAG 275

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
             ++  V+R A  VPESK+   +LKE ++    +A+V+DE+GGVSGLVT+ED+L      
Sbjct: 276 LRTVADVMRPAWFVPESKQALSLLKEMQAADEQLAVVVDEYGGVSGLVTMEDLL------ 329

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHL 250
            E   +  ++            +     +++  E            +T+ G ++   G +
Sbjct: 330 EEIIGEIAEEPSPPSAEPRELELDGGEPVDEVAEQLHIPIPRSPHYETLAGYILHHLGAI 389

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           P+ G+ + + G++ +V   D  RI +V   +PD    P   +
Sbjct: 390 PSEGDELAVSGWRLRVVRMDGHRIDRVRA-VPDAPDAPGASD 430


>UniRef50_A9I003 Magnesium and cobalt efflux protein n=5 Tax=Bordetella
           RepID=A9I003_BORPD
          Length = 298

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 115/294 (39%), Positives = 182/294 (61%), Gaps = 5/294 (1%)

Query: 1   MSDD-NSHSSDTISNKKGFFSLL--LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDM 57
           MSD   ++ ++T   +K   SLL  +  L   EP++R+ + A++  +    L+D ++  M
Sbjct: 1   MSDPYPANDANTNRARKPTKSLLDRMLALVRREPEDREGIKAVLDAAHDRALLDVESYGM 60

Query: 58  LEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGIL 117
           ++G + ++++ V DIM+PRS+M  L  +Q L + L  IIE+AHSRFPV  +D+D+I GIL
Sbjct: 61  IKGALAMSERSVADIMVPRSRMDLLDVSQPLPQQLAFIIETAHSRFPVYEDDRDNIIGIL 120

Query: 118 MAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSG 177
           +AKDLL  M        +  ++R AV +PE+KR++ +L++FR+   H+AIVIDE GG+SG
Sbjct: 121 LAKDLLRGMLEPG--IELRSLIRPAVFIPEAKRLNVLLRDFRASHNHLAIVIDEHGGISG 178

Query: 178 LVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           LVT+ED+LE IVG+IEDE+D++D+        + W + A   I  FNEAF T   D+E D
Sbjct: 179 LVTMEDVLEQIVGDIEDEFDDDDEQSIFPEGDNQWRLMASTEISHFNEAFSTDLPDDEYD 238

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           ++GG +    G +P RG++        +V  AD+RR + +  K   D+ +P  D
Sbjct: 239 SVGGWLGGQLGRIPRRGDSAAHGDLLIEVIRADARRALWLRAKRTSDAAKPGSD 292


>UniRef50_C2HJY2 HCC HlyC/CorC family transporter n=2 Tax=Finegoldia magna
           RepID=C2HJY2_PEPMA
          Length = 414

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 77/273 (28%), Positives = 139/273 (50%), Gaps = 7/273 (2%)

Query: 12  ISNKKGFFSLLLSQLFHGE-----PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           I       + L+ +LF GE         +EL  L+  S +  ++     +++   +++ +
Sbjct: 141 IVKVLNLLTRLVIKLFVGEDEDSSTLTEEELKTLVEVSEEEGVLKNQETEIMINALELKE 200

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
               DIM PR+ M ++       +  ++I    +SR PV  +  D I G+L  K+L   +
Sbjct: 201 TLAVDIMTPRTSMASVDIEDAESDLKEIIKNITYSRIPVYEDSIDDIIGVLHIKELAHKI 260

Query: 127 RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
             D   F +  +L+ A    E   V  + K+ R++   ++I+IDE+GG SG+VT+EDILE
Sbjct: 261 IEDDRDFKIRDILKPAFYAYEYIPVVDLFKQMRAKNISISIIIDEYGGTSGIVTMEDILE 320

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            +VGEI+DEYD E +    ++S + + V     I++ NE F      ++ D+IGG V++ 
Sbjct: 321 ELVGEIDDEYDNEKE--VTKISENEYLVDPEMRIDEVNERFDLDIQSDKFDSIGGFVIEL 378

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
              +P   + ++ +  +F V   D R+I Q+ +
Sbjct: 379 LDRMPKSKDEVEFENLKFVVVNVDKRKITQLMI 411


>UniRef50_C7HS55 Transporter n=3 Tax=Anaerococcus RepID=C7HS55_9FIRM
          Length = 406

 Score =  283 bits (725), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 82/274 (29%), Positives = 141/274 (51%), Gaps = 7/274 (2%)

Query: 17  GFFSLLLSQLF-----HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           G F+  L++       + +    ++L  ++    +  +I+ +  +++  V D A     D
Sbjct: 135 GLFTKYLTKKLSDGADNSDKVTEEDLKTIVDVGEEQGVINNEESEIINNVFDFAGSFASD 194

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM PR+ M  +  + T +E    +IES HSR PV  E  D+I G+L  KD++ F+    E
Sbjct: 195 IMTPRTNMEAIAIDSTKEELDKFLIESKHSRIPVYGESIDNIVGVLHMKDIVTFVAEGRE 254

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  +LRQ     E+  +  + K  +     +AIV+DE+GG  GLV+IEDI+E +VG+
Sbjct: 255 P-RLKDMLRQTYYAYENMNIIDLFKSMKKMNVSLAIVVDEYGGTEGLVSIEDIIEELVGD 313

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DEYD +D+  + ++S + + V A   I DFN+ F     + + D++GGLV+     LP
Sbjct: 314 IYDEYDPDDEKVY-KVSDNEFIVDASMHINDFNDYFNRDIKEVKNDSVGGLVIDYLNRLP 372

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
             G+ + +D         +  +I  + VK   +S
Sbjct: 373 KTGDIVKVDDVTLICEKVERYKINLLRVKFDSES 406


>UniRef50_Q164J1 CBS domain protein n=37 Tax=Rhodobacterales RepID=Q164J1_ROSDO
          Length = 435

 Score =  282 bits (724), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 75/255 (29%), Positives = 135/255 (52%), Gaps = 10/255 (3%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           E+   +       +++++ RD + G +D+ ++ V +IM+ RS +  +  +    + L   
Sbjct: 179 EIEGALTLGHSEGVVEKEHRDRILGALDLNERAVEEIMLHRSGIEMINADDDPQDILHQC 238

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLLPFM----------RSDAEAFSMDKVLRQAVVV 145
           ++S H+R PV  E  ++I G++ AKDLL  M           S   +F +  V  +   V
Sbjct: 239 LQSNHTRLPVFQEHPENIIGVIHAKDLLRAMYKIIGGPEGDASKLRSFKLSDVAMKPYFV 298

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFR 205
           PE+  +D  +++F  +R H A+V+DE+G + GL+T+EDILE IVGEI DE+D  D    +
Sbjct: 299 PETSTLDEQMRQFLRRRTHFALVVDEYGSLQGLITLEDILEEIVGEITDEHDPTDMAPIQ 358

Query: 206 QLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
           Q     + +    +I D N A   +  D+E +T+ GLV+     +P  G+     G++F+
Sbjct: 359 QTEDGQFVIDGAMTIRDLNRAADWNLPDDEANTVAGLVIHEAQMIPTTGQVFSFHGFRFE 418

Query: 266 VAMADSRRIIQVHVK 280
           V   +  RI ++ ++
Sbjct: 419 VCAREGNRITELKIR 433


>UniRef50_C4GJN3 Putative uncharacterized protein n=1 Tax=Kingella oralis ATCC 51147
           RepID=C4GJN3_9NEIS
          Length = 289

 Score =  282 bits (724), Expect = 7e-75,   Method: Composition-based stats.
 Identities = 126/286 (44%), Positives = 173/286 (60%), Gaps = 6/286 (2%)

Query: 11  TISNKKGFFSLLLSQLFH--GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
           T   K   F+ L  ++    G P+   + L L+  +   + +D+DT   LE +       
Sbjct: 5   TPQPKPTLFNRLFHRVSGSIGIPETPAQWLDLLHQAQAQNSLDDDTLLRLENLFKFNQLS 64

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS 128
           VRD M+ R+QM  +K    +D  +   +++AHSRFPVI EDKDHI GIL AKDLL     
Sbjct: 65  VRDAMMTRAQMDVIKTTDGIDRIIAYAVDTAHSRFPVIEEDKDHIIGILHAKDLLKCTL- 123

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           + E F ++ +LR AV VPESK ++ +LK+F++QR HMAIV+DE+GG+SGLVT ED++E I
Sbjct: 124 NPEQFKLEHILRPAVFVPESKSLNSLLKDFQTQRNHMAIVVDEYGGISGLVTFEDVIEQI 183

Query: 189 VGEIEDEYDEEDDID-FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           VG+IEDE+DE+D  D    +S   W ++A   I   NE FGT FSDEE DTIGGLV+   
Sbjct: 184 VGKIEDEFDEDDSADNIFPVSAERWRIKATTEIAAINEYFGTDFSDEEADTIGGLVIHEL 243

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP--DDSPQPKLD 291
           GHLP RGE + +    F VA AD+RR+  +    P       PK +
Sbjct: 244 GHLPVRGEKVQLGDLLFNVARADNRRLHTLMATRPGQKTETTPKAE 289


>UniRef50_D1BMR3 Transporter-associated region n=3 Tax=Veillonella
           RepID=D1BMR3_VEIPT
          Length = 443

 Score =  282 bits (724), Expect = 7e-75,   Method: Composition-based stats.
 Identities = 70/249 (28%), Positives = 132/249 (53%), Gaps = 3/249 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + +E+  +I  S +   +D+   ++++ V +  D+  +++M+PR  +  +      DE +
Sbjct: 184 SEEEIRMMISRSHEEGQLDQVESELIDNVFNFVDRMAKEVMVPRQDVDCVFVEDGYDEAM 243

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
            VI    H+R+P+  EDKDHI G++  KDL+   R +     +  + R  + VPE  ++ 
Sbjct: 244 KVIRSKVHTRYPLCVEDKDHIIGLVHIKDLME--RPNQARKDLRNIKRDILTVPEVMKLS 301

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+  R++R ++A+V+DE+GG+ GLV +EDI+E +VG+I+DE++          +  ++
Sbjct: 302 TLLQYMRTRRIYLAVVVDEYGGMVGLVGLEDIIEELVGDIQDEHEPHLPATM-SYADGSF 360

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
                  +++  E       + + DTIGG V       P  G+T+D  GY F+V      
Sbjct: 361 EFDGKVLVDEVEEIMNIEIDNSDSDTIGGYVFGLLERTPIVGDTVDAHGYTFEVTQMQGY 420

Query: 273 RIIQVHVKI 281
           RI ++ V  
Sbjct: 421 RISRIKVTP 429


>UniRef50_C7LQH5 Putative uncharacterized protein n=1 Tax=Desulfomicrobium baculatum
           DSM 4028 RepID=C7LQH5_DESBD
          Length = 433

 Score =  282 bits (724), Expect = 8e-75,   Method: Composition-based stats.
 Identities = 88/256 (34%), Positives = 132/256 (51%), Gaps = 3/256 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           HG     DEL  LI  S  +  I+E+ R ++    D       + MIPRS++  L    T
Sbjct: 176 HGSVYTEDELRMLIDASYSSGQIEEEKRRLIRRAFDFNTTEACEAMIPRSEIAALPVTST 235

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE-AFSMDKVLRQAVVVP 146
           LDE LD      +SR PV  ED D + G+L  +D+ PFM  +    FSM  +L     VP
Sbjct: 236 LDEVLDAFRIHGYSRLPVYGEDLDDVVGVLFRQDMEPFMAREPGLVFSMTGLLHPPTFVP 295

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
             KR+  +LK+ ++ R H+  V+DE+GG+ GLVT+ED+LE IVGEI DEYDEE      +
Sbjct: 296 SGKRLGSLLKQMQATRTHLIFVMDEYGGLEGLVTLEDVLEEIVGEINDEYDEEVRSQIVR 355

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
                + +  + ++ D N   G    ++E   T+ G ++   G +   G+ + I    FK
Sbjct: 356 -DGTAFILDGMLAVRDLNRKLGLKLPEDEAYTTVAGFLLSEAGRVLEAGDEVPIKEGVFK 414

Query: 266 VAMADSRRIIQVHVKI 281
           V   + RRI+++    
Sbjct: 415 VERLERRRIVRIRFTP 430


>UniRef50_C1XJH4 CBS domain-containing protein n=1 Tax=Meiothermus ruber DSM 1279
           RepID=C1XJH4_MEIRU
          Length = 458

 Score =  282 bits (724), Expect = 8e-75,   Method: Composition-based stats.
 Identities = 96/286 (33%), Positives = 158/286 (55%), Gaps = 6/286 (2%)

Query: 11  TISNKKGFFSLLLSQL----FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
            + N+ G F L L  L     H    + +EL  ++  S +  ++DE   +++  ++D+ +
Sbjct: 164 WLFNRSGNFFLRLMGLKEAPSHSMVGSAEELKLIVEASSKEGVLDESEGEIISQILDLEE 223

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
             VR IM+PR +M+T+    +L +   +  E  +SR PV  E  D+I G+   KDLL + 
Sbjct: 224 TLVRSIMVPRVEMVTISAEASLRDFWAMAREHRYSRVPVYQETIDNIIGVAYIKDLLEYS 283

Query: 127 RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
             + ++  +  +   A  VPE+     +L+E R ++ HMAIV+DEF G +GLVT+EDI+E
Sbjct: 284 GPELDSIKVGSICHPAYFVPETMGARELLREMRRRKTHMAIVVDEFKGTAGLVTLEDIIE 343

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            I+GEI DE DEE+    +Q++   + + A   +E+ ++  G    + E DT+ G +M  
Sbjct: 344 EIIGEIYDESDEEEVAPVQQIAEGVYLLDASVPLEEASKKLGIELPEGEYDTLSGFLMNE 403

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           FGH+P  GE ++  GY+F V  AD R I +V     +  P+P  DE
Sbjct: 404 FGHIPEVGEKLEYGGYEFIVETADPRGIERVR--AQNKIPEPLDDE 447


>UniRef50_D1Y9A3 CBS domain protein n=3 Tax=Propionibacterium acnes
           RepID=D1Y9A3_PROAC
          Length = 432

 Score =  282 bits (724), Expect = 8e-75,   Method: Composition-based stats.
 Identities = 87/270 (32%), Positives = 153/270 (56%), Gaps = 7/270 (2%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   +  EL  ++  +  +DLI+   R+M+  V ++ D   +++M+PR+ ++ + R + L
Sbjct: 163 GPFTSEAELREMVDYAEASDLIEAGEREMIHSVFELGDTLTKEVMVPRTDVVYIPRTKNL 222

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE---AFSMDKVLRQAVVV 145
            + + + + S  SR PV+ E  D I G++  KDL   +  + +     S++ ++R AV+ 
Sbjct: 223 RQAMSLALRSGFSRIPVVGEGFDDIRGVVYLKDLSQRVLDNPDGYATESVESIMRPAVLC 282

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFR 205
           P+SK VD++L+E +  R H+ IV+DEFGG +GLVTIEDI+E IVGEI DEYD E  +   
Sbjct: 283 PDSKPVDQVLREMQRDRNHLVIVVDEFGGTAGLVTIEDIVEEIVGEIVDEYDAEPTLT-E 341

Query: 206 QLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFK 265
           ++    + + +   ++D  E F     D++V+T+GGL+ +    +P  G  I  +G +  
Sbjct: 342 EIEDGVFRISSRLPVDDLGELFDLKVDDDDVETVGGLMAKELSVVPIPGSVIIWEGLEIT 401

Query: 266 VAMADSRR--IIQVHVKI-PDDSPQPKLDE 292
              A  RR  +    VK  P+++P  + D+
Sbjct: 402 AEKATGRRHQVDTCLVKRAPEETPDQEYDD 431


>UniRef50_Q6MCC0 Putative uncharacterized protein n=2 Tax=Parachlamydiaceae
           RepID=Q6MCC0_PARUW
          Length = 457

 Score =  282 bits (723), Expect = 9e-75,   Method: Composition-based stats.
 Identities = 79/239 (33%), Positives = 138/239 (57%), Gaps = 8/239 (3%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           +D   + ++EGVMD  D+  R++M+PR  + +L  + T+++   +I    +SR PV    
Sbjct: 205 LDPHDKKLIEGVMDFKDRIAREVMVPRVDIFSLAHDTTIEQAAVLIYNEGYSRIPVFKHT 264

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFS-------MDKVLRQAVVVPESKRVDRMLKEFRSQR 162
            D+I G+LM KD+L      +           +  +++  +  PE+K++  +L+EFR ++
Sbjct: 265 LDNIIGVLMYKDVLAKYMEFSRTQDTKILQAPISGLVKNVLYTPETKKISHLLQEFRKKQ 324

Query: 163 YHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIED 222
            H+AI++DE+GG  G+VTIEDILE IVG+I DEYDE ++  F  L    W + A  +I D
Sbjct: 325 VHLAIIVDEYGGTEGIVTIEDILEEIVGDIADEYDESEESLFVALPEGGWLIDARMTIFD 384

Query: 223 FNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
             E F    + D + DTIGG +    G++P++G  +    ++ KV  ++ RR+ ++ ++
Sbjct: 385 IEEQFDIEIAQDGDYDTIGGYIFHETGNIPSKGFVLTKPNFELKVIRSNDRRVEKLKIR 443


>UniRef50_D0MK91 CBS domain containing protein n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MK91_RHOM4
          Length = 416

 Score =  282 bits (723), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 83/254 (32%), Positives = 135/254 (53%), Gaps = 13/254 (5%)

Query: 34  RDELLALIRDSGQNDL----IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           + EL   +++          +DE    +L   +     RVRD M+PR+ ++ ++ +  L+
Sbjct: 169 QQELAWQVQEVEAETAPARDLDETESRLLANALAFEKLRVRDCMVPRTDIVAVEEHTDLE 228

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
                 IES +SR PV  E  D I G++ A DL        +  S+ +++R    VPESK
Sbjct: 229 TLRQRFIESGYSRLPVYREHIDQIIGVVFAYDLFR------QPSSLAEMIRPVRFVPESK 282

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF--RQL 207
               +LKEF      +AIVIDE+GG +GLVT ED+LE ++G+I+DE+D ++D ++  R+L
Sbjct: 283 PAHALLKEFLQTNTSIAIVIDEYGGTAGLVTQEDLLEELIGDIQDEFDVDEDEEYLLRRL 342

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
              TW V     I++  EA G    + + DT+ G +++  G +P   E  ++DGY+F + 
Sbjct: 343 DERTWLVSGRVDIDELREA-GLDLPEGDYDTVAGYLLEKLGTIPKPQEEFELDGYRFTIL 401

Query: 268 MADSRRIIQVHVKI 281
            A   RI  V +  
Sbjct: 402 KASQNRIELVRITR 415


>UniRef50_Q6MC55 Putative uncharacterized protein n=1 Tax=Candidatus Protochlamydia
           amoebophila UWE25 RepID=Q6MC55_PARUW
          Length = 419

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 74/241 (30%), Positives = 125/241 (51%), Gaps = 6/241 (2%)

Query: 44  SGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRF 103
             Q  +I E   DM+E +  + ++RV  +MIPR  +  L  N   +E L  I  S H+RF
Sbjct: 178 GSQAGVIREAEHDMVESIFRLGNRRVGILMIPRMDIEWLDLNHHTEELLQQINISPHNRF 237

Query: 104 PVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRY 163
           PV   + D + G++  KD+L  +    + F +  +++  + VPE+ RV ++L  F+    
Sbjct: 238 PVCDGELDKVIGLVTTKDVLNEILKTGK-FDLKTLVKAPLFVPENMRVVQLLDLFKKTPD 296

Query: 164 HMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDF 223
           H+A+V DE+GGV GL+T+ D+LE IVG++        +    Q    +W V  +  I++ 
Sbjct: 297 HIALVTDEYGGVQGLITLHDVLESIVGDVPS-TSILPETQIIQRKDGSWLVDGMLPIDEL 355

Query: 224 NEAFGTH-FSDEE---VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
            E F      +EE     T+GG  M+  G +P  G+T     ++F+V   + RR+ +V +
Sbjct: 356 KEQFDFDSLPEEEKGTYRTLGGFCMRQIGSIPNIGDTFTWQKFRFRVVKMNGRRVEKVLI 415

Query: 280 K 280
            
Sbjct: 416 H 416


>UniRef50_C3MCE9 Putative uncharacterized protein n=1 Tax=Rhizobium sp. NGR234
           RepID=C3MCE9_RHISN
          Length = 431

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 68/269 (25%), Positives = 135/269 (50%), Gaps = 4/269 (1%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
             L+  +    +    +E+ A++    ++  I++   +ML  ++ + D+ V+ IM  R++
Sbjct: 162 MRLMGMKAEDADHVTEEEVHAIMASGVESGAIEKSEHEMLRRIIRLDDRNVKSIMTHRTE 221

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           +  +  N +L+     I +  HSR+PVI      + G ++AK++L    +    F + K 
Sbjct: 222 VSFIDVNDSLETIGRKIRQFGHSRYPVIDGPAGDVVGAVLAKEILNAPIA--APFDIRKY 279

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R+ + +PE+    + L+ F++   +MA+++DE+G   G++T  DILE IVG I   YD+
Sbjct: 280 VREILTLPETATCLKALEAFKASSVNMAMIVDEYGSTEGIITTADILEAIVGVIPSNYDD 339

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTH--FSDEEVDTIGGLVMQAFGHLPARGET 256
            +    R     ++ V     I++ +   G     +D + +TI G ++Q     P  G+ 
Sbjct: 340 IEHAHIRAREDGSYLVDGRTPIDEIHLQIGIEGIDNDGDFETIAGFLVQQLRKTPEEGDC 399

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            +  GY+F+V   D RRI ++ V    + 
Sbjct: 400 AEAHGYRFEVLDMDGRRIDKILVSRRAEE 428


>UniRef50_A8SE58 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=A8SE58_9FIRM
          Length = 434

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 78/278 (28%), Positives = 144/278 (51%), Gaps = 8/278 (2%)

Query: 19  FSLLLSQLFHG---EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           +   L    H    +     EL+ ++ ++  +  + +   +++   ++  D  V +I+ P
Sbjct: 149 WKRFLGHFVHSTEEDTITEGELMTMVSEAENDGELTDRESELIRSAIEFDDVEVEEILTP 208

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  +I ++ +  L+E      ES +SR PV  +  D+I G++  KD   +M    +   +
Sbjct: 209 RVDVIAVEDDMPLEEVAQTFAESGYSRLPVYHDTIDNIIGVVHEKDF--YMARLKKETKL 266

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
           + +++  +    S ++ ++L+  R Q +HMA+V+DE+GG  G++T+EDILE +VGEI DE
Sbjct: 267 EDLVKPTLYTTGSTQISQLLRTLREQHHHMAVVVDEYGGTEGIITLEDILEELVGEIWDE 326

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARG 254
           +DE  + DFR+ S  +W V   A ++D  E  G    ++ + +T+ GLV +    LP  G
Sbjct: 327 HDEVTE-DFRKQSDGSWIVLGSAGVDDLYERLGLPEDEDIDSNTVNGLVQEKTCRLPKVG 385

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           +   +  Y   V     RR+ +V +  P + P  K DE
Sbjct: 386 DRFTLGSYDGVVTRTAKRRVTEVRLT-PAEKPDTKKDE 422


>UniRef50_C9RLZ8 CBS domain containing protein n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RLZ8_FIBSS
          Length = 441

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 84/251 (33%), Positives = 134/251 (53%), Gaps = 4/251 (1%)

Query: 45  GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFP 104
            + + ++++ R M+  + D  +  VR+IM PR  M  +  + +L++ + V+    HSR P
Sbjct: 186 SEGEGLEKEERQMILNIFDFVETPVREIMTPRVDMCAIDVDTSLEDLVKVLNNERHSRLP 245

Query: 105 VISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRY 163
           V  E  D+I GIL  +D L +      E F + K++   V VP  K++D +L E R    
Sbjct: 246 VYKETVDNIVGILSNRDFLEWYTEHHEEPFDLMKLVMPPVYVPYHKKIDDLLTELRKTGN 305

Query: 164 HMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDF 223
            +AIV+DE+GG +GLVT+EDILE IVGEI DE D ++D D ++L    + +  L ++ D 
Sbjct: 306 QLAIVVDEYGGTAGLVTLEDILEEIVGEIRDEDDMDEDEDVQKLKDGRYILDPLMTLSDL 365

Query: 224 NEAFGTHFSDEE---VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
                      E   V+T+ GL+    G +P+ G  + I GY F+V   D  R+ +V + 
Sbjct: 366 EYELDVELKPPENSHVETLSGLIQATLGIIPSPGAEVKIQGYTFRVLRMDGTRMEKVMMI 425

Query: 281 IPDDSPQPKLD 291
           +P     PK  
Sbjct: 426 LPAGVKGPKTQ 436


>UniRef50_B6FN86 Putative uncharacterized protein n=2 Tax=Clostridium
           RepID=B6FN86_9CLOT
          Length = 282

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 78/275 (28%), Positives = 144/275 (52%), Gaps = 11/275 (4%)

Query: 16  KGFFSLLLSQLFHGEPKNRDE----LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +G     + ++F GE +  ++    ++ ++ +  +  +       M+  +    ++  + 
Sbjct: 4   EGNLLSRMRKIFSGEMEEGEDAAEAVMDMVDEGYRQGVFLSSEAQMIRNIFAYGEKDAKS 63

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA- 130
           IM  R  M+ L   +TL+  L  I+E   SRFPV  ED D I G +  +D +    ++  
Sbjct: 64  IMTHRKHMVALDGEETLENALTFILEQNKSRFPVYEEDIDSIIGTIHLRDAMKCYFNEQL 123

Query: 131 ---EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
                  +++ +R    +PE++ +D++LK+ +  +YHMAIVIDE+G  +GLVT+EDI+E 
Sbjct: 124 RHIPIKQLEEYIRPVSFIPETRSIDKLLKKMQEGKYHMAIVIDEYGQTAGLVTMEDIIEE 183

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           IVG I+DEYDEE+++  RQ +  ++    +  +ED  E  G  F +E+ +T+ G ++   
Sbjct: 184 IVGNIQDEYDEEEEL-IRQEADGSYLADGMTEVEDLEELLGIQFEEEDYETLNGFLIFHL 242

Query: 248 GHLP--ARGETIDIDGYQFKVAMADSRRIIQVHVK 280
             +P       +   GY F+V   ++  I  V +K
Sbjct: 243 ERIPTEEENCVVSYGGYDFQVLSMENNIIKTVQIK 277


>UniRef50_A4EBJ7 Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens
           ATCC 25986 RepID=A4EBJ7_9ACTN
          Length = 457

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 82/263 (31%), Positives = 144/263 (54%), Gaps = 6/263 (2%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           +  + +E+  ++  S Q+DL+DE  + M+  + D+ D   R++M+PR      + ++T+ 
Sbjct: 179 QNVSEEEIKYMV--SEQDDLLDE-EKRMIHEIFDLGDTVAREVMVPRVDTTMCEDDETVA 235

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
           + L  + ++  SR PV  ED D++ GI   KDL+           +   LR A  VP++K
Sbjct: 236 DVLSTMRQTGFSRIPVYHEDPDNVAGIAHIKDLIQPALDGKGDQPIAGFLRDATFVPDTK 295

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            +  +L E ++    + +V+DE+GG +G++TIEDI+E IVGEIEDE+D  D+    +LSR
Sbjct: 296 DILPLLSEMQTSHDQIVVVVDEYGGTAGIITIEDIVEEIVGEIEDEFD-PDNKYLTRLSR 354

Query: 210 HTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
             W V    S +D  E  G    + ++ +TI G +++    +P  GE  ++ GY+FKV  
Sbjct: 355 REWLVDGRFSCDDAIE-LGWPLEESDDYETIAGWILELCDSVPDIGEVFEVAGYKFKVQS 413

Query: 269 ADSRRIIQVHVKIPDDSPQPKLD 291
              +RI  + V  P ++ +   +
Sbjct: 414 MRGQRISLIRVIAPAETDKKDSE 436


>UniRef50_D1CH59 Putative uncharacterized protein n=1 Tax=Thermobaculum terrenum
           ATCC BAA-798 RepID=D1CH59_THET1
          Length = 431

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 69/249 (27%), Positives = 129/249 (51%), Gaps = 4/249 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
            + +EL  L+R   +  +++     +     + AD     +M PR+++  +  +  L++ 
Sbjct: 184 HSVEELRFLVRGMREAGVVEPSEARIATRAFEFADVTAGSVMTPRTELEAVPVDTPLEQL 243

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           +     + HSR  V   D D+I G +   D+L  + +      +  ++R A++VPESK  
Sbjct: 244 VAKAATAQHSRLLVYDGDLDNILGDVHVHDILRAVYA-RRPVKLRDLIRPALLVPESKPA 302

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D +L+E R  R  +A+V+DE+GG +G+VTIED++E++VG IE+E         +      
Sbjct: 303 DDLLEEMRKARRPIAVVVDEYGGTAGIVTIEDLVEVLVGPIEEELPPGVREAMQPEEPQ- 361

Query: 212 WTVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
             +  L  + +  E  G    +E+ V+T+GGL+M   G +P  G+ ++I G++ +V   D
Sbjct: 362 -VLDGLMRLRELEEMLGVEIEEEDHVETLGGLIMARLGRIPQEGDEVEIGGHKLRVEKMD 420

Query: 271 SRRIIQVHV 279
             R+  V +
Sbjct: 421 GMRVDSVRL 429


>UniRef50_C1A9X1 Hypothetical membrane protein n=1 Tax=Gemmatimonas aurantiaca T-27
           RepID=C1A9X1_GEMAT
          Length = 433

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 80/263 (30%), Positives = 137/263 (52%), Gaps = 4/263 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
            G   + +EL  L+  +  +  +DE    ML GV D  ++R  D+M PR++M+ +  +  
Sbjct: 175 GGHVHSPEELRLLVMQARAHGTLDESDSAMLAGVFDFHNKRAVDVMRPRTEMVAIAEDVD 234

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
             E  +++    +SR+PV  E  D I G+ +AKD   ++R ++E+F + +VLR+ + VP 
Sbjct: 235 QQELEEILRRERYSRYPVYRETADDIVGVFLAKDF--WLRENSESFELRQVLREPLFVPA 292

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           ++  +R+L + R  R H+A+V+DEFGG +G+VT+ED++E +VG+I DEYD         L
Sbjct: 293 TRTAERVLDDLRRTRAHLAVVLDEFGGTAGIVTMEDLVEEVVGDIADEYDPLSRDAL--L 350

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
                 +    S+ D          + +  T+GG      G LP  G+ +   G   +V 
Sbjct: 351 FDGVLELAGSMSLVDVRSDHKLPIPEGDWSTLGGYAFATLGRLPHVGDRVAYPGGDLEVV 410

Query: 268 MADSRRIIQVHVKIPDDSPQPKL 290
             D RR+  + V    +S +P  
Sbjct: 411 AMDGRRVAALRVHKRVESTEPAA 433


>UniRef50_Q1IKR3 CBS domain protein n=1 Tax=Candidatus Koribacter versatilis
           Ellin345 RepID=Q1IKR3_ACIBL
          Length = 422

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 86/269 (31%), Positives = 151/269 (56%), Gaps = 7/269 (2%)

Query: 22  LLSQLFHGEPKNRDE-LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI 80
           L  +    EP++  E + ALI    +  +++E  R +++ V++  D+ VR++M PR ++ 
Sbjct: 154 LAKENAEEEPEHPSEAVDALIEAGTEEGILEESDRHLIQSVVEFGDKTVREVMTPRPRIF 213

Query: 81  TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLR 140
            +  + TL++  D + +  +SR PV     D++ GI+ ++DLL    +DA    +  ++R
Sbjct: 214 AVPTDWTLEQLTDALRDQGYSRIPVFRGSIDNLVGIVFSRDLLQIADTDARTRKVGDLVR 273

Query: 141 -QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
            + + VPE+KR   +L+E +     MA+VIDE+G V+GLVTIED++E IVGE+ DE    
Sbjct: 274 EELMFVPETKRGSELLREMQRDNVRMAVVIDEYGSVAGLVTIEDLIEEIVGELRDE---- 329

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETID 258
           D+ D  +   HT+ V     ++  NE FG    ++ E  T+ GLV +  G +P  GE ++
Sbjct: 330 DETDIVKEGEHTYVVPGSMDVDRLNELFGVRVDEDHESSTVAGLVSEIAGRIPQPGEVVE 389

Query: 259 IDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             G +F+V  +  RRI ++ +     +P 
Sbjct: 390 NLGLRFEVLASTDRRIERLRISEATQTPD 418


>UniRef50_D1VTC9 Integral membrane protein n=1 Tax=Peptoniphilus lacrimalis 315-B
           RepID=D1VTC9_9FIRM
          Length = 412

 Score =  281 bits (719), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 82/264 (31%), Positives = 131/264 (49%), Gaps = 1/264 (0%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           F  L  S   +      ++L   +       L+D +   M+E VMD  D   +DIM PR+
Sbjct: 148 FLKLTGSFDINEPLITEEDLYDAMNRGKAEGLLDHNESLMIENVMDFRDSYAKDIMTPRT 207

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            ++ +    +  E +D+I +   SR PV  ++ D+I GIL  KDL   M           
Sbjct: 208 DIVAIDIESSYSEIIDLICKENFSRMPVYEDNIDNIIGILNVKDLF-MMNKHKSLKENKS 266

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
             ++     E K V  +  + R+ +  +AIV DE+GG +G++TIED++E IVG I DEYD
Sbjct: 267 FFKKPYFTYEYKEVSSLFSDMRANKISVAIVADEYGGTTGMITIEDLIEKIVGAINDEYD 326

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
            EDD D  +L  + + V    +++D N+  G      E D+IGG +++     P + E I
Sbjct: 327 NEDDEDIIKLGPNKYLVDGAMNLDDLNQLTGLELESTEFDSIGGFIIEKIDRFPKKNEVI 386

Query: 258 DIDGYQFKVAMADSRRIIQVHVKI 281
            +D  +F V      RI +V ++I
Sbjct: 387 ILDNLKFTVKKTSKNRIDKVLLEI 410


>UniRef50_C8P0P9 CBS domain protein n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414
           RepID=C8P0P9_ERYRH
          Length = 442

 Score =  281 bits (719), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 73/263 (27%), Positives = 143/263 (54%), Gaps = 12/263 (4%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           +    +E+  ++        ID   ++M+  + +  +  V DIM  R++++ +  + +  
Sbjct: 176 DEVTEEEIRIMVD----AGEIDVTEKEMINNIFEFDNLDVADIMTHRTEVVGIDVSSSFA 231

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS--DAEAFSMDKVLRQAVVVPE 147
           + ++++ E  ++R+PV  +  D+I G++  +DLL +++   D E F + K++R+   VP+
Sbjct: 232 DIMELVDEERYTRYPVYEDSIDNIIGLIHLRDLLRYVKDHRDDEVFEIKKIIREPYYVPD 291

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           SKR D + +E ++ + H A+VIDE+GG +G+VT+ED++E I+G I DEYDEE++ +   +
Sbjct: 292 SKRTDELFRELQNSKMHFAVVIDEYGGTAGIVTMEDLIEEIMGNIMDEYDEEEEQEIVAV 351

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET------IDIDG 261
           +   + V     IED  +    +   E+ DT+ G V+   G LP   +       +   G
Sbjct: 352 NLDEYLVDGACDIEDLEDVININLPVEDYDTVSGFVVGQIGRLPTEEDVREDLSDVIYHG 411

Query: 262 YQFKVAMADSRRIIQVHVKIPDD 284
           Y+F +   D + I +V V    +
Sbjct: 412 YRFSIMELDEKVIARVRVTKEKE 434


>UniRef50_A5ZVW9 Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC
           29174 RepID=A5ZVW9_9FIRM
          Length = 315

 Score =  281 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 82/306 (26%), Positives = 161/306 (52%), Gaps = 15/306 (4%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFH------GEPKNRDELLALIRDSGQNDLIDEDT 54
           M D +       +    +   L  ++FH       +     E+++++ ++ +  ++ +D 
Sbjct: 1   MDDGSRLPRRGPAKVIDWIQGLFFRVFHFFKGEQEDSVTEKEIISMVDEAHEKGVLQKDE 60

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
            +M++ +    D+ V  +M  RS +     +  L + ++ ++E  +SR+PV  ED D I 
Sbjct: 61  AEMIQNIFAFEDKEVGVVMTHRSSVAAFAMDDLLKDVVNHMMEEENSRYPVCGEDMDDIR 120

Query: 115 GILMAKDLLPFMRSDAEA-----FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVI 169
           G++  KD L F   +  A       +  ++R+A  VPE++ + ++ +  ++++ HMA+V+
Sbjct: 121 GLIHYKDALKFFTQNPWAKFKPLKELPGLIRKATFVPETRHIGQLFRTMQARQVHMAVVV 180

Query: 170 DEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT 229
           DE+G  +G+VT+ED++E IVG+I DEYDE  D  FR    ++  +  LAS++D  +    
Sbjct: 181 DEYGQTAGIVTMEDLIEEIVGDIFDEYDESRD-TFRTQVDNSIIIDGLASLDDVEQELDI 239

Query: 230 HFSDEEVDTIGGLVMQAFGHLPARGE---TIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
            F D E++T+ G + +  GH+P+R +    I  +GY+FK+    +R I +V  +  +D  
Sbjct: 240 EFGDVEMETLNGYLTELLGHIPSREDLDKEIVANGYRFKILSLGNRTIGRVRAEKINDKE 299

Query: 287 QPKLDE 292
                E
Sbjct: 300 TKGESE 305


>UniRef50_A4FLP3 Magnesium and cobalt efflux protein CorC n=3 Tax=Actinomycetales
           RepID=A4FLP3_SACEN
          Length = 426

 Score =  281 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 77/257 (29%), Positives = 133/257 (51%), Gaps = 5/257 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
            +   ++EL  ++R + Q   +  + R +L    +  D+ + ++MIPR+++  L R  +L
Sbjct: 173 ADKVTQEELRDMVRTNEQ---LTVEERKLLTDAFEAGDRVLSEVMIPRTEVDFLDRTMSL 229

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE-AFSMDKVLRQAVVVPE 147
            + +  + +  HSR+PVI +  D + G L  +DLL     +   A ++  + R    +P 
Sbjct: 230 ADAVAKVRDQPHSRYPVIRDTADDVVGFLHVRDLLTTTHDNRSGARTIGDLARPVTSLPG 289

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           SK V   L   R +  H+A+V+DE+GG +G+VT+ED++E +VGEI DEYD       R  
Sbjct: 290 SKPVLSALTVMRRRGGHLAVVVDEYGGTAGIVTVEDLVEEVVGEIWDEYDT-GVAPVRPS 348

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
              ++ +  +    +  E  G    D   DT+ G VM   G +PA G+ ++  G++F V 
Sbjct: 349 PEGSYELDGMLHRSEVEEHTGISLPDGPFDTLAGFVMAELGRMPAEGDAVEALGHRFTVR 408

Query: 268 MADSRRIIQVHVKIPDD 284
             D RRI +V +    D
Sbjct: 409 ELDGRRIARVLITPLGD 425


>UniRef50_A1QYK9 Magnesium and cobalt efflux protein CorC n=21 Tax=Borrelia
           RepID=A1QYK9_BORT9
          Length = 259

 Score =  281 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 88/231 (38%), Positives = 132/231 (57%), Gaps = 2/231 (0%)

Query: 54  TRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHI 113
              +L+    + +  V++IMIPR  ++ +  + + DE L V+  S HSRFPV  E  D I
Sbjct: 28  ETSLLKNFNSLKETIVKEIMIPRISVVFVDYSWSKDEILKVVTSSNHSRFPVYRETIDDI 87

Query: 114 EGILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEF 172
            GI+  KD+L  M + D     +  ++R+ + VPESK++D +LKEF+    H+AIV+DE+
Sbjct: 88  IGIIHTKDILLHMWKRDFYEIDLRDIMRKVMFVPESKKIDSLLKEFQENHVHIAIVVDEY 147

Query: 173 GGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS 232
           GGV+GLVT+EDILE IVG+I+DE+D E D +   L   ++   A   IED NE  G    
Sbjct: 148 GGVAGLVTLEDILEEIVGDIQDEFDNELD-EIVPLDDGSYLCTARVLIEDLNEKLGLSLP 206

Query: 233 DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           D + DT+GG V   FG +P + E I  +   F +     R I  + +   +
Sbjct: 207 DGDFDTLGGFVYDLFGRIPLKNEKIKYNNLTFTIKNMHQRNIKVIKISQKE 257


>UniRef50_Q0G3C6 Putative uncharacterized protein n=2 Tax=Aurantimonadaceae
           RepID=Q0G3C6_9RHIZ
          Length = 444

 Score =  281 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 81/267 (30%), Positives = 142/267 (53%), Gaps = 5/267 (1%)

Query: 22  LLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT 81
            +S+    E    +++ ++I++  Q  +  E  R+MLEGV+ IAD+ VR IM+PR  +  
Sbjct: 167 FVSEDDKEEEVTEEDVRSMIKEGTQLGVFKEKEREMLEGVIRIADRNVRSIMVPRPDVDW 226

Query: 82  LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQ 141
           L  + + DE  + II + HSRFPV+  ++D I GI+  KDL    R +     +   +R+
Sbjct: 227 LSVHDSEDENFEEIIRAGHSRFPVLDTEEDAIVGIVQTKDLFELQRREGR-MDLKTAMRK 285

Query: 142 AVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD 201
            + V E+  + ++L+ FR    H+A+V+DE+G   G+ T +DIL  I G +  E  EED 
Sbjct: 286 PLYVNEAMPILKLLEAFRKANLHIAVVLDEYGSFEGIATPQDILTAIAGSLP-EGAEEDV 344

Query: 202 IDFRQLSRHTWTVRALASIEDFNEAFG-THFSDE-EVDTIGGLVMQAFGHLPARGETIDI 259
             FR+    +W V     ++ F        F ++ + +T+ G V++  GH+P  GE  + 
Sbjct: 345 SAFRRQ-DGSWLVDGAMPVDAFAYKLKTIEFPEDRDYETVAGFVLEQIGHIPGVGEIFEW 403

Query: 260 DGYQFKVAMADSRRIIQVHVKIPDDSP 286
           + ++ +V   D +RI ++       +P
Sbjct: 404 ENFRVEVVDLDGQRIDKLLFTEKAAAP 430


>UniRef50_C0FYH2 Putative uncharacterized protein n=1 Tax=Roseburia inulinivorans
           DSM 16841 RepID=C0FYH2_9FIRM
          Length = 316

 Score =  280 bits (718), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 72/279 (25%), Positives = 146/279 (52%), Gaps = 10/279 (3%)

Query: 7   HSSDTISNKKGFFSLLLSQLFHGEP--KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDI 64
               + +      S  L +LF  +      +E+++++ +  +  ++  +  +M+  + + 
Sbjct: 26  DDGGSPTTGMKKLSNRLMKLFGVDTDDVTEEEIISMVNEGHEQGVLQANEAEMIHNIFEF 85

Query: 65  ADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP 124
            D+  +DIM+ R  +I +    T  E LD  IE+ +SR+PV  +D D+I G+L  K++L 
Sbjct: 86  GDKDAKDIMVHRKNIIAIDGTMTFLEMLDFTIENNYSRYPVYIDDIDNIIGVLHIKEVLA 145

Query: 125 FMRSDA----EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
             +           +  ++R+   +PE++ ++ +    ++ + HM IV+DE+G  SG+V 
Sbjct: 146 LCQKQEIYHTAIKDIKGLIREVDFIPETRNINTLFTMMQNAKTHMVIVVDEYGQTSGIVA 205

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE-VDTI 239
           +EDILE IVG IEDE+D+E+ +   +L   ++ +  + S E+  E    H  +E+  +T+
Sbjct: 206 MEDILEEIVGNIEDEHDQEEKM-IEKLPDGSYLMDGMTSAEEALEILKIHIPEEDEFETL 264

Query: 240 GGLVMQAFGHLPARGETIDID--GYQFKVAMADSRRIIQ 276
            G+++     +P   E  + D  GY F+V   +++ I +
Sbjct: 265 NGILISLLDRIPNDDEKFETDAFGYHFEVLQVENKMIKK 303


>UniRef50_A0JX40 CBS domain containing protein n=4 Tax=Micrococcaceae
           RepID=A0JX40_ARTS2
          Length = 447

 Score =  280 bits (717), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 86/244 (35%), Positives = 145/244 (59%), Gaps = 4/244 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + +E   L+  + ++D+I+++  ++++ V D  D  VR +M+PR+ ++++    +L   +
Sbjct: 163 SEEEFRELVDRATESDMIEDNEAELIQSVFDFGDTLVRAVMVPRTDILSIDAGSSLHRAM 222

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS---DAEAFSMDKVLRQAVVVPESK 149
            + + S +SR PVI ++ D I GI+  KD+   +       E   +D + R+   VPESK
Sbjct: 223 SLFLRSGYSRIPVIRDNTDQILGIIYLKDVAAALHGLGPGEEPPIVDDLAREVRYVPESK 282

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
           +V  +L+E + +  H+AIVIDE+GG +GLVT+ED++E IVGEI DEYD E   +   L  
Sbjct: 283 QVSDLLRELQKESTHVAIVIDEYGGTAGLVTLEDLIEEIVGEIVDEYDTE-SAEAVALGN 341

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
            ++ V A   I+D  E F     D+EVDT+GGL+ +A G +P  G T+++DG   +    
Sbjct: 342 GSYRVSARMGIDDLGELFDVELDDDEVDTVGGLLAKALGRVPIVGSTVEVDGISLRAERL 401

Query: 270 DSRR 273
           + RR
Sbjct: 402 EGRR 405


>UniRef50_A8ZTS5 Putative uncharacterized protein n=2 Tax=Desulfobacteraceae
           RepID=A8ZTS5_DESOH
          Length = 422

 Score =  280 bits (717), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 76/272 (27%), Positives = 136/272 (50%), Gaps = 4/272 (1%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
            F   L  ++        +EL A+I  + +   ID + ++ +  +  + D    + M P 
Sbjct: 142 NFIPRLTGKMKPIPVMTEEELKAIIEVTEEEGEIDNEEKEFIHNIFKLDDTSASESMTPT 201

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
           + M  +  N+ L   L  I+++ ++R PV      +I GIL  KD+           ++ 
Sbjct: 202 TDMFAVDVNKKLP--LGAILKTGYTRIPVYEHHIGNIIGILNVKDVFRHYVQAKGPPNIR 259

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
            ++ +   +PESK+++ +LK+F+ +++HMAIVI+E G V GL+T+ED+LE +VG+I DE 
Sbjct: 260 SLMSKPYFIPESKKLNSLLKQFKLRKHHMAIVINEHGEVLGLITLEDVLEELVGDIIDET 319

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGE 255
           D   +    ++ + TW V     IE+ N     H  +  E DT  G ++   G +P  GE
Sbjct: 320 DR-YEPHIVKVKKQTWLVLGKTHIEETNAKLPMHIPESGEYDTFSGYLLYRIGRIPEEGE 378

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            I ID +   +   ++ RI+ + V+     P 
Sbjct: 379 IITIDNFVITIKRMEANRILSLLVEEKASPPS 410


>UniRef50_C0EHV3 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
           DSM 5476 RepID=C0EHV3_9CLOT
          Length = 428

 Score =  280 bits (717), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 71/282 (25%), Positives = 137/282 (48%), Gaps = 3/282 (1%)

Query: 12  ISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           + N     +   ++          EL  ++ +     ++++    ++   +D  +    +
Sbjct: 148 LFNGLKKLTERFTKSDSQPSVTEQELKVIVEEIESEGVLEDHESQLVRSALDFDETTAEE 207

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +++PR  +++++ N +++E   + +    SR PV     D+I G+L  KD       + E
Sbjct: 208 VLVPRVDIVSVEVNASVEEMKQLFLTERFSRVPVYERSIDNIVGVLYEKDFFRSYIQNGE 267

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  +L+Q + +P   ++  +LK+ +S R HMA+V D++GGV G+VT+ED+LE +VGE
Sbjct: 268 NIDIRGLLQQPLFIPPQTKISDLLKQIQSVRAHMAVVTDQYGGVEGIVTLEDVLEELVGE 327

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS--DEEVDTIGGLVMQAFGH 249
           I DE DEE   D ++L    + V    ++ED  E  G        + +T+GG V +   H
Sbjct: 328 IYDE-DEEIVEDVQRLGSGLYRVNPDMAVEDLFEEIGFEPKNFSSDSNTVGGWVFELLEH 386

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           +P  GE +  +     V     +RI  + V + + S   + D
Sbjct: 387 IPEPGEQVSFEELTLTVTDLSDQRIRSLEVHLGESSDPEQQD 428


>UniRef50_C2BH63 HCC HlyC/CorC family transporter n=2 Tax=Anaerococcus
           RepID=C2BH63_9FIRM
          Length = 415

 Score =  279 bits (716), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 80/266 (30%), Positives = 142/266 (53%), Gaps = 4/266 (1%)

Query: 17  GFFSLLLS--QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
            F + L+       G+    ++L  ++  S +  +I++   +++  V +  D  V DIM 
Sbjct: 150 NFLTRLIIGENAQKGDIVTEEDLKTIVDVSEEQGVINDQESEIINNVFEFGDSDVEDIMT 209

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
            R+ M  +  +    E  D +    HSR PV  +  D+I GIL  KD++ F+  D E  +
Sbjct: 210 ARTNMEAIAVDMEDKELKDFLKNCKHSRIPVYGKSIDNIIGILHMKDIVAFIAEDKE-LN 268

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +++++R A  V ++  +  + K+ R +   +AIVIDE+GG SG+VTIEDI+E +VGEIED
Sbjct: 269 IEEMVRPAFYVYDNMHIFDLFKQMRGENVSLAIVIDEYGGTSGIVTIEDIVEELVGEIED 328

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARG 254
           EYD   +    +++   + V     I DFN+ F T     + D+IGG ++   G +P  G
Sbjct: 329 EYDTHLE-TVLKINDKEYLVNPSIHINDFNDYFDTDLEQIKNDSIGGFLIDKLGRIPKLG 387

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVK 280
           ++++ DG +  V   +  ++  + V+
Sbjct: 388 DSVEEDGIKISVVQINRYKLEMLKVE 413


>UniRef50_UPI0001BC3544 hypothetical protein BcroD2_01764 n=1 Tax=Butyrivibrio crossotus
           DSM 2876 RepID=UPI0001BC3544
          Length = 443

 Score =  279 bits (716), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 78/260 (30%), Positives = 137/260 (52%), Gaps = 7/260 (2%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E    +E++ ++ +  +  +++    +M+  + ++ D+   DIM  RS +  ++   TLD
Sbjct: 173 ENVTEEEIITMVNEGQEQGVLEAGEAEMITNIFELGDKHAGDIMTHRSNIEAVESTITLD 232

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA----FSMDKVLRQAVVV 145
             +   IE  +SRFPV   D D+I G +  +D L F R+          +  +LR+  +V
Sbjct: 233 NFIQNHIEGKYSRFPVYEGDIDNIVGTIHIRDALIFYRNIPNRKKLLKDIKGLLRKPYMV 292

Query: 146 PESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFR 205
           PE+  +D MLK+ + ++ HM IV+DE+G  +G+V++EDI+E IVG I DEYD+E+++   
Sbjct: 293 PETMDIDDMLKDMQEKKIHMGIVVDEYGQTAGIVSMEDIIEEIVGNILDEYDDEEEVVEY 352

Query: 206 QLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET--IDIDGYQ 263
                T+ V  L  IED N   G     +  +T+ G ++   G + +  ET  I+  G+ 
Sbjct: 353 A-GDDTYVVDGLTDIEDINSLLGIKIESDGFETLNGFLISKLGRIASENETEVIEAYGFS 411

Query: 264 FKVAMADSRRIIQVHVKIPD 283
           FK+       I +V +   D
Sbjct: 412 FKILEVTGNVIRKVEITKID 431


>UniRef50_A4J4V5 Putative uncharacterized protein n=1 Tax=Desulfotomaculum reducens
           MI-1 RepID=A4J4V5_DESRM
          Length = 445

 Score =  279 bits (715), Expect = 8e-74,   Method: Composition-based stats.
 Identities = 82/257 (31%), Positives = 137/257 (53%), Gaps = 5/257 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H +  + +E+  ++  S +   I +    +    +  AD+   +IM+PR  M+ L  N +
Sbjct: 175 HHQIHSEEEIRMILLQSHKGGEITQTELQLARNSLHFADRVAAEIMVPRPDMVCLYTNLS 234

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD----KVLRQAV 143
            +E L +I E  ++R+PV   DKD+I G +  KDL     +D    +++    + LR+A+
Sbjct: 235 WEENLKIITEEKYARYPVCDGDKDYIIGFVNTKDLCFSGLTDLNMLNLEGFLKQALRKAM 294

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
           VV E   +D +LK+ +  R  MAIV DE+GG +GL+T+EDILE IVGEI+DE+DEE  + 
Sbjct: 295 VVTELTPIDEILKKMQKNRLQMAIVQDEYGGTAGLLTLEDILEEIVGEIQDEHDEERQL- 353

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
              L  + +++ A   I DFN  F      + V T+ G   +     P +G+T+     Q
Sbjct: 354 IESLGGNRYSLDARLPIADFNLEFDLDLKAKGVYTLAGWFQEESHRTPEKGQTVRYKNLQ 413

Query: 264 FKVAMADSRRIIQVHVK 280
           F ++  D   I ++ + 
Sbjct: 414 FSISEIDKNTIRRIEMT 430


>UniRef50_C0W312 HCC HlyC/CorC family transporter n=1 Tax=Actinomyces urogenitalis
           DSM 15434 RepID=C0W312_9ACTO
          Length = 432

 Score =  279 bits (715), Expect = 9e-74,   Method: Composition-based stats.
 Identities = 86/263 (32%), Positives = 151/263 (57%), Gaps = 7/263 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           ++L  +I + G+ + I+++ R ML  V+++    VR++M+PR+ M+T+  ++ +   + +
Sbjct: 168 EDLREMIDEIGEAETIEDEDRQMLRSVVELGQTLVREVMVPRTDMVTIDADKPVSAAMRL 227

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE--AFSMDKVLRQAVVVPESKRVD 152
            I+S  SR PVI +D D + G++  KDLL  + +  E     +   +R+AV VPE+K  D
Sbjct: 228 FIKSGFSRVPVIGQDADDVRGVVYLKDLLRRLDAQPEYAQREVVTCMREAVYVPETKLAD 287

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+E ++   HMA+ +DE+GG +GLVT+ED+LE +VG++ DE+D  +  +   L    +
Sbjct: 288 DLLREMQTDSVHMALAVDEYGGTAGLVTMEDLLEEVVGDMTDEHDHAEP-EVEDLGDGVY 346

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V A  S+++  E FG    D++VDT GGL+ +A G +P  G + ++ G       A  R
Sbjct: 347 RVPARLSLDELGELFGLEIDDDDVDTAGGLLTKAIGRVPLPGASGEVQGLHLVADQATGR 406

Query: 273 R--IIQVHV--KIPDDSPQPKLD 291
           R  +  + V    PD +     D
Sbjct: 407 RRQVTSLLVSASRPDTAQTTSKD 429


>UniRef50_B9Y7L5 Putative uncharacterized protein n=1 Tax=Holdemania filiformis DSM
           12042 RepID=B9Y7L5_9FIRM
          Length = 399

 Score =  279 bits (714), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 75/281 (26%), Positives = 141/281 (50%), Gaps = 9/281 (3%)

Query: 17  GFFSLLLSQLFHGE---PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
             +  LLS +F  E      ++ELL ++ ++     ++    D++   ++  D  V+DI+
Sbjct: 109 SLWKKLLSMMFKVENDDSMTQEELLTIVEEAQNEGDLEAHESDLICAAIEFNDLDVKDIL 168

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR  +I +    +LDE   +   +  SR PV     D+I G++  KD      +    F
Sbjct: 169 TPRVDVIAVDVTDSLDEIELMFRNNNFSRLPVYENSIDNIVGVIHEKDFYNLYYNHMGTF 228

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
               + +  +      ++  +LK+ +S + HMA+V+DE+GG +G++T+EDILE +VGEI 
Sbjct: 229 --KSITQTLLYTSPHVKISSLLKQLQSSKTHMAVVLDEYGGTAGIITLEDILEELVGEIY 286

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD--TIGGLVMQAFGHLP 251
           DE+D+  +  +++L  +T+ +     ++D  E FG    +E+ D  T+ G V+     +P
Sbjct: 287 DEHDQVKEY-YKELDPNTYLIECDMDLDDMFEFFGLE-DEEDYDFITVSGWVIHELERIP 344

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
             GE+         V   D+R++I+V V +       + D+
Sbjct: 345 KVGESFTYKNLVVTVTQTDARKVIEVKVSVIPQDQSEEDDD 385


>UniRef50_Q6N606 Probable HlyC/CorC family of transporters with 2 CBS domains n=12
           Tax=Alphaproteobacteria RepID=Q6N606_RHOPA
          Length = 431

 Score =  279 bits (714), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 77/277 (27%), Positives = 131/277 (47%), Gaps = 4/277 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           + K   +LL       +  + +E+ +L+ ++    +++   R M+ GVM + D+ V  +M
Sbjct: 157 SGKAMLALLGQSGEPEDKISEEEIHSLVMEAETAGILEPGERQMIAGVMRLGDRPVGAVM 216

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR ++  +  +   D+       S HSR P    D+D   GI+ +KD+L       E  
Sbjct: 217 TPRPEVDMIDLSDPPDQIRATFASSPHSRLPATDGDRDDPIGIIQSKDVLEVYLRG-ETP 275

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
               ++R A V+P S      L   R+   HM +V DEFGG  G+V+  DILE IVG   
Sbjct: 276 DFRALVRDAPVIPASADARDALIMLRNASVHMGLVYDEFGGFEGVVSTADILESIVGAFS 335

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPA 252
            E D   +    +    ++ V     +++F +  G       +  T+ GLV+   G LP+
Sbjct: 336 SE-DGPPEPAAVRRDDGSYLVAGWMPVDEFGDLLGMPVPAPRDYHTVAGLVLSHLGALPS 394

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHV-KIPDDSPQP 288
            G+  D  G++F++   D RRI ++   ++PDD   P
Sbjct: 395 VGDKFDFQGWRFEIMDLDHRRIDKILASRLPDDEASP 431


>UniRef50_C6J7K3 Putative uncharacterized protein n=2 Tax=Bacillales
           RepID=C6J7K3_9BACL
          Length = 454

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 78/243 (32%), Positives = 144/243 (59%), Gaps = 3/243 (1%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           +  L+  S ++ +ID+D   +++ + D +D   R++M+PR+ M  L  N + ++ + ++ 
Sbjct: 200 IRILMDQSAKSGVIDKDEMKLVDNIFDFSDMLAREVMLPRTDMDCLYTNLSWEDNMKIVA 259

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLK 156
            + HSR+PV  EDKD I G +   DLL  +    +   +++++R  + VPES  + ++L+
Sbjct: 260 NTKHSRYPVAVEDKDQIIGFVHITDLL--LPDSEKPLRLEEMVRPILNVPESMEISQVLR 317

Query: 157 EFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRA 216
             + +   + +V+DE+GG +GL+T E+ILE IVG++ DE+++E   D  +++   ++V  
Sbjct: 318 LMQKKHSQVTLVVDEYGGTAGLLTAEEILEEIVGDLHDEFEDERP-DIEKITDDVYSVDG 376

Query: 217 LASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ 276
              IE+ NE  G+   DEEVD+IGG + +     PA+G+   +D + F+V  A   RI +
Sbjct: 377 RLLIEEVNELVGSDIEDEEVDSIGGWLFKELEGTPAKGKRKQVDRFLFEVEEASRLRITR 436

Query: 277 VHV 279
           V V
Sbjct: 437 VKV 439


>UniRef50_Q01WS1 Putative uncharacterized protein n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01WS1_SOLUE
          Length = 446

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 85/263 (32%), Positives = 140/263 (53%), Gaps = 13/263 (4%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           HG     +EL  ++  S     + E   DM+  V+D+    VR+IMIPR+ ++++  + +
Sbjct: 178 HGNVHTSEELKLIVSSSRGLGYLPETQEDMIHRVLDLGALSVREIMIPRNDIVSISTDAS 237

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA---------EAFSMDKV 138
           LDE L  + E  HSR PV  +  + I G+L  KDLLP               ++F + ++
Sbjct: 238 LDEVLHTMNEQRHSRLPVYEKTPEKIVGLLHYKDLLPVWEERRLAIRSSRPSQSFRVSRL 297

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R  + VPE+K V  ML EFR  R HMA+++DEFG + G+VT+ED+LE IVG+IEDE+DE
Sbjct: 298 MRPLMFVPETKEVSAMLDEFRHGRSHMAMIVDEFGTIIGMVTVEDVLEQIVGQIEDEHDE 357

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETI 257
             +   RQ+      +     I D    +G     +   +T+ G ++   G +P     +
Sbjct: 358 RVE---RQVEADDVELDGTTRIRDLESEYGIEIPPDAGFETLAGFLLFKLGEIPRVESRV 414

Query: 258 DIDGYQFKVAMADSRRIIQVHVK 280
           + +G ++ V   +  RI +V ++
Sbjct: 415 EYEGRRYTVLEMERNRIARVRIE 437


>UniRef50_A9M203 Magnesium and cobalt transporter n=27 Tax=Neisseriaceae
           RepID=A9M203_NEIM0
          Length = 274

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 138/273 (50%), Positives = 178/273 (65%), Gaps = 3/273 (1%)

Query: 10  DTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           D    K  FF  L+++L   EP + +++L L+R + + ++ D DT   LE V+D +D  V
Sbjct: 2   DGAQPKTNFFERLIARLAR-EPDSAEDVLNLLRQAHEQEVFDADTLLRLEKVLDFSDLEV 60

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           RD MI RS+M  LK N +++     +I++AHSRFPVI EDKD + GIL AKDLL +M  +
Sbjct: 61  RDAMITRSRMNVLKENDSIERITAYVIDTAHSRFPVIGEDKDEVLGILHAKDLLKYMF-N 119

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            E F +  +LR AV VPE K +  +LKEFR QR HMAIVIDE+GG SGLVT EDI+E IV
Sbjct: 120 PEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVIDEYGGTSGLVTFEDIIEQIV 179

Query: 190 GEIEDEYDEEDDID-FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           GEIEDE+DE+D  D    +S   W + A   IED N  FGT +S EE DTIGGLV+Q  G
Sbjct: 180 GEIEDEFDEDDSADNIHAVSSERWRIHAATEIEDINTFFGTEYSSEEADTIGGLVIQELG 239

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           HLP RGE + I G QF VA AD+RR+  +    
Sbjct: 240 HLPVRGEKVLIGGLQFTVARADNRRLHTLMATR 272


>UniRef50_Q87DZ3 Hemolysin n=20 Tax=Xanthomonadaceae RepID=Q87DZ3_XYLFT
          Length = 448

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 68/258 (26%), Positives = 132/258 (51%), Gaps = 4/258 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +E+  L+ +S +  +ID+  R+M+  VM + D+    +M PR+++  L  +  L+  
Sbjct: 184 VTEEEIRLLVAESHEAGVIDDYERNMMNRVMRLGDRTADSLMTPRNRIAWLDNSADLEHN 243

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE-AFSMDKVLRQAVVVPESKR 150
           L+++ E   SR+PV       I GIL  K ++  + S  +   S+ + L + V V ES  
Sbjct: 244 LEIMREHQFSRYPVYRSSDQDIVGILEVKSVITRIDSQTQTTLSLFQELCEPVFVSESTH 303

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH 210
             ++L+ FR ++  MA+V+DE+G + GLVTI D++  ++G +++  + ++D         
Sbjct: 304 ALKLLEIFREEQQSMALVVDEYGEILGLVTISDLMGAVIGRLQNVENTDEDALMVTREDG 363

Query: 211 TWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
           ++ +     IE+  E  G    D E     T+ G+ +  FG +P  GE  D  G++ ++ 
Sbjct: 364 SFLIDGTLPIEELREVLGAELPDGEENNYHTLAGMCISYFGRIPHVGEYFDWAGWRIEIV 423

Query: 268 MADSRRIIQVHVKIPDDS 285
             D  RI ++ ++  +  
Sbjct: 424 DLDGARIDKLLLQRLNKE 441


>UniRef50_B3QY17 CBS domain containing protein n=1 Tax=Chloroherpeton thalassium
           ATCC 35110 RepID=B3QY17_CHLT3
          Length = 436

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 72/278 (25%), Positives = 133/278 (47%), Gaps = 12/278 (4%)

Query: 25  QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKR 84
           +         +E+ AL     +   + +    ++E ++D  +Q VR IM PR+ +  +  
Sbjct: 160 KSLSVSSLTNEEIKALAESGLERGELTDTEHLLIENILDFREQIVRKIMTPRADICAIDT 219

Query: 85  NQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--EAFSMDKVLRQA 142
             + DE +++I     S+ P+  +D D+I G+L AKDL+ F  +    +     K  R  
Sbjct: 220 EASWDELVELIRNKKISKIPLYEDDLDNILGVLHAKDLVKFTNAKRQLKPEDWHKNARPP 279

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
           + VPE++R+D +LK F+ +   +AIV+DE+GG SG+VT++DI++ I+GE+          
Sbjct: 280 IFVPETQRLDDLLKTFQKKHTQVAIVVDEYGGTSGIVTLDDIIQEILGELA--ATPPSQA 337

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFS--------DEEVDTIGGLVMQAFGHLPARG 254
           D++Q+    +   A   IE+  E                ++ DT+GG ++   G +P   
Sbjct: 338 DYKQIGTDCYRFDARIPIEEAFEVLNLPIHHPNKESDYSDDFDTLGGFILNLCGGIPNEK 397

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           + I  +    ++     +RI+ V +     SP     E
Sbjct: 398 QHIQYENLDIEIEKILGQRILSVIICTKQTSPPNPSQE 435


>UniRef50_Q8YM44 All5096 protein n=16 Tax=Cyanobacteria RepID=Q8YM44_ANASP
          Length = 436

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 73/270 (27%), Positives = 130/270 (48%), Gaps = 12/270 (4%)

Query: 23  LSQLFHGE--------PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           L +LF  E        P   +EL  +I    ++  ++   R++L  + +  D   +D+MI
Sbjct: 166 LLRLFGVEYTGQSWRPPVTPEELQLIISTERESTGLEMAERELLNNIFEFGDVTAQDVMI 225

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR+ +I L ++      L  +  + HSR+PVI E  D I GI+  +DL   +     +  
Sbjct: 226 PRNGIIALSKDANFQNLLQQMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAIGKLSLE 285

Query: 135 --MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +   +R    VPE   +  +L   + ++  M IV+DEFGG  GLVTI+D++  I+G  
Sbjct: 286 TQIQPWMRPVRFVPEHTPLSELLPMMQQEKPAMVIVVDEFGGTVGLVTIQDVIAEIIGN- 344

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLP 251
             E    +D+  + L + T+ V+A  ++ED NE    +     +  T+ G ++     +P
Sbjct: 345 AGETSSSEDLLIQMLDQETFLVQAQVNLEDLNEVLHLNLPLTRQYQTLAGFLLYQLQKMP 404

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
            +GE    D  +F +   D  R+ Q+ ++ 
Sbjct: 405 IKGEIFCYDNIEFTIVSVDGPRLHQIQLRR 434


>UniRef50_C6LCF2 CBS domain protein n=1 Tax=Bryantella formatexigens DSM 14469
           RepID=C6LCF2_9FIRM
          Length = 289

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 74/274 (27%), Positives = 145/274 (52%), Gaps = 9/274 (3%)

Query: 12  ISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           + +  G  S  L +   G  +  +E+++++ +  +  +I E    M++ + D+ D+  +D
Sbjct: 2   LKSLSGLLSRKLGKNPSGSDEYEEEIISMVNEGHEQGVIQESQAQMIQNIFDLTDKEAQD 61

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M  R  +  ++    L + L  +++  HSRFPV  ++ D+I GIL  KD + +   + +
Sbjct: 62  VMTHRRNITAIEGTMNLKDALAFMLDDTHSRFPVYLDNLDNIIGILFLKDAMRWHTRNPD 121

Query: 132 -----AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
                   +  +LR+AV +PE++ +  + K  ++Q+  M IV DE+G  +GLV +EDILE
Sbjct: 122 YDNWQIKDIPSLLRKAVFIPETRDLSPLFKSMQTQKLQMVIVSDEYGQTAGLVAMEDILE 181

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            IVG I+DEYD ++ +  +      + +   A +++ +EA      D E +T+ G ++  
Sbjct: 182 EIVGNIQDEYDNDEPVIEKAGDD--FLISGFAPLDEVSEALQLSLDDVEFETLNGFLISK 239

Query: 247 FGHLPARGE--TIDIDGYQFKVAMADSRRIIQVH 278
            G +P+  +   I  DGY F++    ++ I +V 
Sbjct: 240 LGRIPSDDDRSEIITDGYSFRILSVANKTIERVR 273


>UniRef50_A6LDG3 Hemolysin-related protein n=23 Tax=Bacteroidales RepID=A6LDG3_PARD8
          Length = 450

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 96/232 (41%), Positives = 143/232 (61%), Gaps = 7/232 (3%)

Query: 52  EDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKD 111
            + ++ML  ++   ++   +IM PR  M  ++   +  E +D II+S +SR PV SE +D
Sbjct: 203 PEEKEMLAEIIKFYNKTADEIMTPRLDMEDIEIKISFREVVDFIIKSGYSRIPVYSETED 262

Query: 112 HIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDE 171
           +I+GIL  KDLLP++    + F    ++R A  VPE+K++D +L+EFR+ + HMAIV+DE
Sbjct: 263 NIKGILYIKDLLPYI-DKPDTFRWQSLIRPAYFVPETKKIDDLLEEFRTNKIHMAIVVDE 321

Query: 172 FGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF 231
           FGG SG+VT+EDILE IVGEI DEYDE++    R L+  +    A   + DF        
Sbjct: 322 FGGTSGIVTMEDILEEIVGEISDEYDEDEQQFIR-LADGSLIFEAKILLTDFFRVIDADP 380

Query: 232 SD-----EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVH 278
           SD     EEV+T+ GL+++  G  P R E ID   Y+F+V   D+RRI++V 
Sbjct: 381 SDFGKLTEEVETLAGLLLEIKGDFPRRREIIDFKEYRFQVLEVDNRRILKVK 432


>UniRef50_Q1K2A8 Putative uncharacterized protein n=1 Tax=Desulfuromonas acetoxidans
           DSM 684 RepID=Q1K2A8_DESAC
          Length = 461

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 75/282 (26%), Positives = 130/282 (46%), Gaps = 9/282 (3%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +  G   LL  +         +++LA++ +  Q  +I++    +   V  + D+    +M
Sbjct: 180 STDGVLRLLGKEGHTSATLTEEDILAILLEGSQTGVIEKQEHTLARNVFRLDDRLAVSLM 239

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PRS ++ L   +  ++ LD ++ S H+RFPV  E  D + G++ A  LL +        
Sbjct: 240 TPRSDIVYLDVARPFEQSLDALMSSPHTRFPVCREGMDEVLGVVNASRLLKYHLEGNLQK 299

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
                L  AV VPES    ++L+ F++    M  VIDE+G + GL+T++D+ E + GE  
Sbjct: 300 PTKSDLTPAVYVPESLTGMKLLQRFQTSGVQMVFVIDEYGAIVGLITLQDLFEALSGEFS 359

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFGH 249
               +  D+   +     W +  L  I +  +        DEE     T+GG++M   G 
Sbjct: 360 S--SDPHDVWAVRHKDGAWMLDGLIPIPELKDRLELKQVPDEEKRHYHTLGGMMMCLIGK 417

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVH-VKIP--DDSPQP 288
           +P  G+     G+  +V   D  RI +V  V++P   DS  P
Sbjct: 418 VPRSGDVAKWQGWSLQVTALDGNRIDKVRAVRLPRRHDSTSP 459


>UniRef50_A6U9C9 Putative uncharacterized protein n=2 Tax=Sinorhizobium
           RepID=A6U9C9_SINMW
          Length = 430

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 65/256 (25%), Positives = 132/256 (51%), Gaps = 4/256 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +E+ A++ +  ++  I++   +ML  ++ + D+ V+ IM  R+++  +     L+  
Sbjct: 175 VTEEEVQAIMAEGVESGAIEKSEHEMLRRIIRLGDRNVKTIMTHRTEVSFIDIQDDLETI 234

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
              I +S HSR+PV+      + G ++AK++L   ++    F++   +R  + +PE+   
Sbjct: 235 GHKIRQSGHSRYPVVDGPAGDVIGAVLAKEILNVSQTGK--FNIRDYVRDILTLPETASC 292

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
            + L+ F++   +MA+++DE+G   G++T  DILE IVG I   YD+ +          +
Sbjct: 293 LKALEAFKTSSINMAMIVDEYGSTEGIITTADILEAIVGIIPSNYDDSEHALIHLRDDGS 352

Query: 212 WTVRALASIEDFNEAFGTH--FSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
           + V     I++ +   G     +D + +TI G ++Q     P  G+T +  GY+F+V   
Sbjct: 353 YLVDGRTPIDEIHLQIGIEGIDADSDFETIAGFLVQQLRKSPEEGDTAEAHGYRFEVIDM 412

Query: 270 DSRRIIQVHVKIPDDS 285
           D RRI ++ V    ++
Sbjct: 413 DGRRIDKILVSRAGEA 428


>UniRef50_B1I646 Putative uncharacterized protein n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I646_DESAP
          Length = 431

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 79/257 (30%), Positives = 140/257 (54%), Gaps = 5/257 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           + +    DEL  +I        +D + + +L  V D  D    D+M+PR+ ++ ++ + +
Sbjct: 179 NEDQVTEDELKQII---VNQSTLDREEQRLLWDVFDFGDAVAYDVMVPRTDVVGVETSTS 235

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           + + L ++ E+ HSR PV  ++ D I+GI   KDL+P++    E   ++KV+R A VVP 
Sbjct: 236 VADTLRLMSETGHSRIPVYGQNLDDIKGIAGIKDLVPYLLRGEEQAPVEKVVRPAYVVPN 295

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  + ++L++ + +   MA+++DEFGG  G+VT+E +LE +VGEI DEYD ED  +    
Sbjct: 296 TVPIRQLLRDLQKRGVSMAVIVDEFGGTDGVVTVETLLEELVGEIRDEYDREDQ-EILSS 354

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
                 V+  A +++ N        + EE  TI G ++     +P  G+ + +DG   +V
Sbjct: 355 EDGQAIVKGSAGVDEVNRQLKLAIPESEEYHTIAGFILDQLNKVPKAGDRVTLDGTVLEV 414

Query: 267 AMADSRRIIQVHVKIPD 283
           A   + RI+ V +K  D
Sbjct: 415 AKMKANRILMVSIKKED 431


>UniRef50_UPI0001C360F2 putative hemolysin-related protein n=2 Tax=Clostridium hathewayi
           DSM 13479 RepID=UPI0001C360F2
          Length = 436

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 83/275 (30%), Positives = 138/275 (50%), Gaps = 5/275 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
             K   SLL+ +         +ELLA++ ++ Q+  IDE    +++  ++  +    DI 
Sbjct: 162 QWKKLLSLLI-RTSGDPGITEEELLAIVEEAKQDGGIDEQEGSLIKSAIEFTELEATDIA 220

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR  +  +  +   +E   V  E+ +SR PV  E  D I GI+  KD    M       
Sbjct: 221 TPRVDVTGISIDADKEEIAAVFDETGYSRLPVYKETIDDITGIIYQKDFYNRMYRG--TC 278

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            ++ ++R A+ V +SK+++ +LKE +  + H+A+VIDEFGG  G+VT+EDILE +VGEI 
Sbjct: 279 GVEAIVRPALYVAKSKKINVLLKELQKNKMHIAVVIDEFGGTMGIVTLEDILEELVGEIW 338

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DE+D     +  ++S   + V   AS+E      G+  + E   T+ G VM+    +P  
Sbjct: 339 DEHDVVVQ-EIEKISDREYLVSGNASVEKLMGELGSEETFESF-TVSGWVMELAERIPEE 396

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           G+    D     V     RR+ QV + +  +  +P
Sbjct: 397 GDVFYYDHMSITVIKMRDRRVEQVRLVLEAEPMEP 431


>UniRef50_Q01P08 CBS domain containing protein n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01P08_SOLUE
          Length = 420

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 78/263 (29%), Positives = 142/263 (53%), Gaps = 4/263 (1%)

Query: 27  FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQ 86
            + EP   + + ALI    +  LI+E+ R +++ V++  D+ VR++M PR  ++ +  + 
Sbjct: 160 ANEEPTPAENIEALISAGTEEGLIEEEDRKLIQSVVEFGDKVVREVMTPRPNIVAIAADA 219

Query: 87  TLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVP 146
           TL++   ++I   +SR PV     D++ G +  +D+      + E  ++  ++R  ++VP
Sbjct: 220 TLEQLRQLVITEQYSRIPVYEGTIDNVIGFVHVRDMFELQEEEREKRTVRGLVRNIMLVP 279

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           E+K V  +++  + +  HM IV+DE+G  +GL T+ED+LE+I+GEI DE+  E D D  +
Sbjct: 280 ETKPVSVLMRRMQQENTHMVIVVDEYGNTAGLATMEDLLEVIIGEIRDEH--EPDSDVAE 337

Query: 207 LSRHTWTVRALASIEDFNEAFGT--HFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQF 264
             R  + V     ++   +   T     D E  T+GGLV +  G +P  GE ++ DG + 
Sbjct: 338 DGRGGFIVSGSFDLDRITDLIDTFHRGDDIESTTVGGLVSEWLGRVPKTGEFVERDGVRL 397

Query: 265 KVAMADSRRIIQVHVKIPDDSPQ 287
           +V  +D  R+ QV +       Q
Sbjct: 398 EVLASDELRVGQVRISKSQTVAQ 420


>UniRef50_B3WFB2 Transport protein n=8 Tax=Lactobacillus RepID=B3WFB2_LACCB
          Length = 448

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 91/269 (33%), Positives = 147/269 (54%), Gaps = 6/269 (2%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           GE   RDE++++I     +  ID D   M EG++ ++D   R++M+PR+    +   +  
Sbjct: 178 GETVTRDEMVSMIESGRNSGAIDPDEYQMFEGIISLSDTMAREVMVPRTDAFMVDAQEPD 237

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS-DAEAFSMDKVLRQAVVVPE 147
              +D I+ + +SR PV  EDKDH+ GI+  K+LL   R    +   ++ V+   V VPE
Sbjct: 238 HTAIDAILNNIYSRIPVYEEDKDHVVGIVHIKNLLKEARRVGFDHVKIESVMTAPVFVPE 297

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  VD +L E + ++  MAI++DE+GGV G+VTIED+LE IVGEI+DE D+ + + F + 
Sbjct: 298 TITVDDLLTEMQVKQQQMAILLDEYGGVVGIVTIEDLLEEIVGEIDDESDQVEKL-FTKQ 356

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARG--ETIDI-DGYQF 264
             H + V     I DFN+ F T     +VDTI G V+   G +P+    E + +  G   
Sbjct: 357 GDHDFVVSGRMPISDFNDLFKTDLDAPDVDTIAGYVLTQLGAIPSSHHSEKMQLAPGVLL 416

Query: 265 KVAMADSRRIIQVHVKIPDDS-PQPKLDE 292
                +  R++ VH+ +  +  P+    E
Sbjct: 417 ATGKVEGSRLVNVHIHLSSEPVPEEASHE 445


>UniRef50_UPI000050F785 CBS domain-containing protein n=1 Tax=Brevibacterium linens BL2
           RepID=UPI000050F785
          Length = 417

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 83/260 (31%), Positives = 145/260 (55%), Gaps = 5/260 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G     D+L  L+  + ++D+I++  R+M++ V +++D    ++M+PR+ ++T+     L
Sbjct: 159 GPFVTSDQLRDLVERASESDVIEDGEREMIQSVFNLSDTSANEVMVPRTDLVTVNSGTPL 218

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP--FMRSDAEAFSMDKVLRQAVVVP 146
            + +++   S  SR PV  ED D I G+   KD+     +  +     +D + R  + VP
Sbjct: 219 SKVMNLFFRSGFSRIPVSGEDLDDIRGVAYLKDVARRLHLHPEDAERPVDILARGVLFVP 278

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           E+K  D ++++ +    H+AI+IDE+GG +GLVTIEDI+E IVGEIEDEYD  DD +  +
Sbjct: 279 ETKPADDLMEQMQVDSTHLAILIDEYGGTAGLVTIEDIVEEIVGEIEDEYDTSDD-ELVE 337

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
           +   ++ V    SI DF + F     +++V+++GGL+ +  G +P  G    I+G   + 
Sbjct: 338 VDDGSFVVSTRMSISDFADYFDVKIDEDDVNSVGGLLTKLIGRVPIDGSNARIEGLIIEA 397

Query: 267 AMADSR--RIIQVHVKIPDD 284
                R  RI  V V   ++
Sbjct: 398 MEGQGRRHRITHVRVTKEEN 417


>UniRef50_A0LRV3 Putative uncharacterized protein n=1 Tax=Acidothermus
           cellulolyticus 11B RepID=A0LRV3_ACIC1
          Length = 438

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 75/257 (29%), Positives = 136/257 (52%), Gaps = 7/257 (2%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  + +EL  L+     ++ +  D R +++ V    D+R+R++++PR+++  L     + 
Sbjct: 177 ESMSEEELRGLV---TSHEALGRDERQLIDEVFTAGDRRLREVLVPRTEVEFLDATMPVG 233

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD-AEAFSMDKVLRQAVVVPES 148
           + L  +  + HSR+PV     D I G++  +DLL     +      +  ++R   ++P+ 
Sbjct: 234 QALAQLRSTMHSRYPVFRGSHDEIIGMVHVRDLLAAQAENRGRTVRVGDLVRPVKLLPDG 293

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             V + L E R + + +A+V+DE+GG +G+VT+ED++E I+GEI DE+  +        +
Sbjct: 294 LGVLQALSEMRREGHRLAVVVDEYGGTAGIVTLEDLVEEIIGEIRDEHAPD---GVDASA 350

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
                V  L   EDF E  G    D   +T+ G ++ A GH+P  GE +D+DGY+F VA 
Sbjct: 351 SGEMIVDGLTHTEDFAEETGIRLPDGPYETVAGFMLAALGHIPGLGEWVDVDGYRFTVAE 410

Query: 269 ADSRRIIQVHVKIPDDS 285
            D RR+ ++ +      
Sbjct: 411 LDGRRVAKIKITRRPTE 427


>UniRef50_C0QRS4 CBS/transporter-associated domain protein n=5 Tax=Aquificales
           RepID=C0QRS4_PERMH
          Length = 429

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 81/275 (29%), Positives = 148/275 (53%), Gaps = 3/275 (1%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
              + L         + D+L++++    +  +  E+ ++++E  + + +  V +IM PR 
Sbjct: 154 LKKMGLELPVESHKLSEDDLISIVNIGTEKKIFTEEEKEIIEATLQLHETAVSEIMTPRR 213

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            +  + +  T+ E L++I E  +SR PV   + D+I GIL  KD++ F++ + +   +D+
Sbjct: 214 DIFAIPKGLTVREVLELIKEKDYSRIPVYEGNLDNIIGILYIKDII-FLKFEGKEEKIDR 272

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
            LR+   VPE   +  ++K+F  ++ HMAIV+DE G V GLVT +DILE IVG+I  E  
Sbjct: 273 FLREPYFVPEFTPLLNLMKKFEEKKNHMAIVVDEHGTVVGLVTFQDILEFIVGDIP-EEY 331

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGET 256
           E ++   +Q+S + W V     +E   E  G    D+ E DT+GG ++      P  GE 
Sbjct: 332 EPEEPFIKQISMNKWEVSGKIEVEILEEVVGIKLPDDYEFDTVGGFILDVLKRFPEEGEE 391

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
              + Y+F++   +S RII V ++   ++ + + +
Sbjct: 392 FVYENYKFRILKMESNRIISVLIEKLPETVKEEEE 426


>UniRef50_C4GBW1 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
           DSM 14600 RepID=C4GBW1_9FIRM
          Length = 458

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 85/266 (31%), Positives = 137/266 (51%), Gaps = 3/266 (1%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
             E    +EL  ++  S +  +I+ + R+ +  + D  D  VR++MIPR  +     N +
Sbjct: 163 RRENLTEEELRTIVDVSQEAGVIEHEERNYIHNLFDFTDSNVREVMIPRIDVTVANVNWS 222

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
            D+ + V      +R PV  E+ D I GI+  KDLL  +  D   FS+   LR A    E
Sbjct: 223 YDKLISVFAGCMFTRLPVYDENSDSIVGIINMKDLL--LVKDKAHFSLRDYLRSAYFTFE 280

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
            K    + +E R     MAIV+DE+G  +G++++ED+LE +VGEI DEYD  ++ D  QL
Sbjct: 281 LKNTRELFEEMRQNSIAMAIVMDEYGAFAGIISLEDLLEELVGEIRDEYDSNEEDDIVQL 340

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET-IDIDGYQFKV 266
           +   + V    ++ED        +  E+ DTIGG +   F H P +GET +D +G   KV
Sbjct: 341 NEREYLVVGSMNLEDLMSIIPLGYESEDYDTIGGYLTGEFDHFPNQGETYVDSNGAILKV 400

Query: 267 AMADSRRIIQVHVKIPDDSPQPKLDE 292
                 RI ++ +++P+   +   +E
Sbjct: 401 EKVRKNRITKILIRLPEQIAKEVDEE 426


>UniRef50_A5CRB2 Conserved membrane protein n=4 Tax=Actinobacteria (class)
           RepID=A5CRB2_CLAM3
          Length = 440

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 83/252 (32%), Positives = 151/252 (59%), Gaps = 6/252 (2%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + ++LL+++ ++ + ++++ED R+++  + +  D  VR++MIPR+ M+ +++   +   L
Sbjct: 162 SEEQLLSMVDEATELEVLEEDDRELIHSIFEFNDTVVREVMIPRTDMVVVEQTAHVGSAL 221

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS---DAEAFSMDKVLRQAVVVPESK 149
            + +    SR PV   D D IEG+L  +DL   +     +AE  ++D++ R AV VPES+
Sbjct: 222 GLFLSRGISRAPVTGRDSDEIEGVLYLRDLARMVYERPEEAERTTVDQLARPAVFVPESQ 281

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
           + D +L++ + +  H+A+V+DE+GG++GLVT+ED++E +VG+I DEYD  D  +F  L  
Sbjct: 282 KADALLRQMQLESNHLAMVVDEYGGIAGLVTLEDLIEELVGDISDEYDR-DVPEFEDLGD 340

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
             + V A   I++  + FG    D++VD+ GGL+ +  G LP RG  + + G        
Sbjct: 341 GVYRVSARLPIDELGDLFGLELDDDDVDSAGGLLAKTLGRLPERGSVVRVGGLVLTADRV 400

Query: 270 DSR--RIIQVHV 279
           + R  RI  + V
Sbjct: 401 EGRRTRISTILV 412


>UniRef50_A9NGP1 Putative hemolysin-related protein n=2 Tax=Bacteria
           RepID=A9NGP1_ACHLI
          Length = 422

 Score =  277 bits (709), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 78/253 (30%), Positives = 145/253 (57%), Gaps = 5/253 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + DEL+ ++ +  ++  IDE +  ++   ++ AD    DI  PR  ++ +      ++  
Sbjct: 164 SEDELIMIVDEVQESGAIDESSGTLIRSAIEFADLEAVDIYTPRIDVVAVSTAARHEDIF 223

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
            V  ES +SR PV  E+ DHI G++  KD    +    E F + ++++  + +P++K+V 
Sbjct: 224 KVFKESGYSRIPVYEENIDHIIGVMNYKDFFMVLT---EGFDIKEIIKDVLFIPKTKKVK 280

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L E +  + HMA+VID++GG +G++T+EDILE +VG+I DE+D+  +   ++++ + +
Sbjct: 281 DLLLELQQSKSHMAVVIDDYGGTAGILTLEDILEELVGDIWDEHDDIIEA-VKKMNDNQY 339

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V   +SIEDF E  G+   +  V T+ G V++  G LP  G+T ++  Y F++   D +
Sbjct: 340 LVLGNSSIEDFLEIIGSK-EEPNVLTVNGWVVEKLGTLPVEGKTYEVKPYTFEIVKMDGK 398

Query: 273 RIIQVHVKIPDDS 285
           RI  V + I  + 
Sbjct: 399 RIDLVQITIEKEE 411


>UniRef50_C4L4N6 Putative uncharacterized protein n=2 Tax=Bacillales
           RepID=C4L4N6_EXISA
          Length = 424

 Score =  277 bits (709), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 72/265 (27%), Positives = 132/265 (49%), Gaps = 2/265 (0%)

Query: 16  KGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           K     ++           +EL  L+    +  ++ E   +++       D  V D++ P
Sbjct: 150 KKLTLRMIGMKDKEPSVTEEELKVLVDMGEEEGVLGETEAELVHSAFAFNDITVDDVLTP 209

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  ++ +  + +LDE  D I    HSR PV  +  D++ G+L  +D L  M  D E   +
Sbjct: 210 RIDILAVDIDDSLDEIKDTIFSGGHSRLPVYKDSIDNVIGVLSERDFLRSMMKD-EVTDV 268

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
             ++R    V    ++  +L   + ++ HMA+V+DEFGG +GL+T+ED+LE +VG+I DE
Sbjct: 269 RSLIRPLTYVSPQTKLIELLPILQQKQSHMAVVLDEFGGTAGLITLEDMLEELVGDIWDE 328

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
           +DE   +  R+L    +   A  ++++F E  G    D + +T+GG  ++  G +P +G 
Sbjct: 329 HDES-VVYLRRLREGVYECMADMNVDEFAEEMGIAEPDVDSNTMGGWFVELLGDIPEKGA 387

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVK 280
            +      F V   + RR+ ++ V+
Sbjct: 388 QVTYQDMTFTVLHVEKRRVRKLLVE 412


>UniRef50_Q609I4 CBS domain protein n=2 Tax=Proteobacteria RepID=Q609I4_METCA
          Length = 432

 Score =  277 bits (709), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 63/271 (23%), Positives = 131/271 (48%), Gaps = 6/271 (2%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
             LL ++         +E+  L++      + +E  + ++E ++ +  ++V  IM PR  
Sbjct: 162 LRLLGARPVRQPSVTEEEIKLLLQQGTLEGVFEEVEQKLVENILRLDSRKVGAIMTPRKD 221

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           ++ L   ++ +    ++ +  H   P+     D++ G +  KD+L  + +  +   + ++
Sbjct: 222 VVYLDVTKSYEANRGILTDHPHWIIPLCRGGVDNVLGFVKTKDVLNRLLAGEKP-ELAEL 280

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           + +A+ VP S  + ++L+ F+      A+V+DE+G ++GLVT+ D+LE IVG I  E  E
Sbjct: 281 VTRALFVPNSLSLMQLLEHFKRSHLQTALVVDEYGELTGLVTLTDVLEAIVGAIASETAE 340

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFGHLPARG 254
           E+     Q    +W +  +  IE F + F      +EE     T+ G VM   G++P   
Sbjct: 341 EEP-QVSQREDGSWLIDGMLDIERFKQLFDLDALPEEETGNFHTMAGFVMLRLGNVPKVT 399

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           ++ +    +F+V   D  R+ ++ V     +
Sbjct: 400 DSFEFQDLRFEVVDMDRNRVDKILVTRLPPA 430


>UniRef50_UPI000196CD6F hypothetical protein CATMIT_02806 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196CD6F
          Length = 427

 Score =  277 bits (709), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 81/266 (30%), Positives = 150/266 (56%), Gaps = 2/266 (0%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           G   +L   +      + ++L  ++  S +  +++++ ++M+  + D  D  +++IM PR
Sbjct: 151 GLIHILGGNIDPQPTLSEEDLKTIVNVSHEEGVLEDEEKEMMHNIFDFGDTDIKEIMTPR 210

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
             + T+  + T DE + V+ ES +SR PV+SE+ D I G+L  KD+L     D E F + 
Sbjct: 211 IHVATVDYDATYDEVVAVLQESQYSRLPVLSEEGDEIVGVLHIKDIL-MKPVDHEHFQVK 269

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
             +R A  V E   +  +    R +   +++V+DE+G ++G+VT+EDI+E IVGEI+DEY
Sbjct: 270 DYMRDAYFVYEFNHISDVFASMRKEHVSLSVVLDEYGVMAGIVTLEDIVEEIVGEIDDEY 329

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           D+  + + +++S++ + V    +I++ N+  GT F+ EE ++IGGLV+      P   + 
Sbjct: 330 DDNSE-EVKKISKNVYLVDGSLNIDEVNDRCGTEFASEEFESIGGLVLGQVNGSPNPHQK 388

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIP 282
           + +D   F +   D  RI  + + IP
Sbjct: 389 VYVDDCMFIIEKIDKNRIELLRLIIP 414


>UniRef50_A6CIW3 Probable hemolysin n=2 Tax=Bacillus RepID=A6CIW3_9BACI
          Length = 445

 Score =  277 bits (709), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 79/277 (28%), Positives = 146/277 (52%), Gaps = 11/277 (3%)

Query: 18  FFSLLLSQLFHGEP------KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           F S  + +LF  +P         +++  ++    +   I+   + M+  + +  D+   D
Sbjct: 159 FSSNTVIRLFGIDPNEQNEEATEEDIRMMVDIGRERGTINTVEKVMINNIFEFNDKIASD 218

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           I+  R+ M  L  +  L+E L+++ +  ++RFPV  + +D+I G+L +KDL  ++  D E
Sbjct: 219 IITHRTDMCVLSIDADLEEVLEMVSKEGYTRFPVYEKVRDNIVGVLHSKDLFQYIGKD-E 277

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            F +  V+R+   V ES+ +D +    ++   H+AIV+DEFGG  G++TIED++E IVGE
Sbjct: 278 DFDLRNVIRKPYFVLESQTIDVLFTTMQTNNVHIAIVLDEFGGTEGMITIEDVIEEIVGE 337

Query: 192 IED--EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           I      +   + + +Q+S + + V+ +A + +       HFS EE+DT+ G ++   G+
Sbjct: 338 IYSESIEEGIYEEEIKQISPNQYEVKGIARLWELEAVLKVHFSTEELDTLSGFLIHELGY 397

Query: 250 LPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
            P+  E   ID    QF+V      R+ +  V +  D
Sbjct: 398 FPSVQERPVIDYKHLQFEVLEIKDNRVEKAMVTVKTD 434


>UniRef50_C6HVJ5 Putative uncharacterized protein n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HVJ5_9BACT
          Length = 460

 Score =  277 bits (709), Expect = 4e-73,   Method: Composition-based stats.
 Identities = 83/242 (34%), Positives = 136/242 (56%), Gaps = 3/242 (1%)

Query: 47  NDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVI 106
           + +I+   +D+++ V    D  VR++M+PR +M+TL+   TL E + +  E+ +SR+PV+
Sbjct: 197 HGIINRTEQDLIQSVFKFTDISVREVMVPRVRMVTLRTGMTLSEIIGIFSENRYSRYPVL 256

Query: 107 SEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMA 166
             + + + GIL  KDL+  + +    F +DKVL     VPES +V  +LKE + +R  MA
Sbjct: 257 RAEGEEVAGILYYKDLVELLNAPG-TFRIDKVLHTPYFVPESMKVPYVLKEMQKRRTQMA 315

Query: 167 IVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEA 226
           +V+DE+G + GLVT+ED+LE IVGEIEDE DE       +L   ++ V A  SI D +E 
Sbjct: 316 LVLDEYGALDGLVTMEDLLEEIVGEIEDESDEVAKP-VERLRDGSYLVDASLSIRDLSED 374

Query: 227 FGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           +     + E+ +T+ G V+     +P  GE       +  V   D +R+ +V ++  D  
Sbjct: 375 YRIPIPEGEDYETLAGFVLSQLQTIPRGGEFFFSKNMKVTVVEVDRQRVSRVRIEFLDAP 434

Query: 286 PQ 287
             
Sbjct: 435 AS 436


>UniRef50_A7VCA4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VCA4_9CLOT
          Length = 433

 Score =  276 bits (708), Expect = 5e-73,   Method: Composition-based stats.
 Identities = 82/275 (29%), Positives = 148/275 (53%), Gaps = 4/275 (1%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           F+ L +      +    DEL+ ++  S +  +I+   ++M+  V+D  D RVRDIMIPR+
Sbjct: 156 FWILHMDTNESAKSITEDELITMVNVSEEEGVIENKEKEMITNVVDFGDSRVRDIMIPRT 215

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF-MRSDAEAFSMD 136
            +  +    T DE L   +E  ++R PV  + +D++ GIL  KDL  +    D   F + 
Sbjct: 216 DVTMVPVTATYDELLKQYMEVPYTRLPVYKDSRDNVIGILHVKDLFFYKATHDINNFDVT 275

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
            ++R+   V E ++ + +L   +S    + IV+DE+G   GL+++ED++E I+G+I+DEY
Sbjct: 276 NIVREPFYVYEFQKTNDLLANMKSSSNSIGIVLDEYGVCVGLISMEDLIEEIIGDIKDEY 335

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           D+ +  +  ++    +++     ++D N+A       E+ D+IGG ++Q   HLP+ G+T
Sbjct: 336 DDAEHNNIVKIDDTHYSIDGGIKLDDLNDALDLDIESEDYDSIGGYIIQLLDHLPSVGDT 395

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
                   KV   D  R+ +V ++I    P+P  D
Sbjct: 396 ASDGVISCKVTKLDKNRVSRVLLEI---LPKPNTD 427


>UniRef50_C7PAX6 Putative uncharacterized protein n=1 Tax=Chitinophaga pinensis DSM
           2588 RepID=C7PAX6_CHIPD
          Length = 433

 Score =  276 bits (708), Expect = 6e-73,   Method: Composition-based stats.
 Identities = 74/276 (26%), Positives = 144/276 (52%), Gaps = 12/276 (4%)

Query: 18  FFSLLLSQLFHGEPK-----NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
            F+  L  +F+ +P        +E+ ALI +   +  I+E  ++++E V  + D+ +  +
Sbjct: 156 IFTNFLVNIFNLKPTVDSNATEEEIKALINEGATSGAIEETEQEIIERVFHLGDRNITSL 215

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M  R+ ++ L  N   +     I ES HS +PV  ++ D+I GI+  KDL  +M +    
Sbjct: 216 MTHRTDIVWLDVNDPKEIIRSKIFESPHSVYPVCDDEIDNIRGIISIKDL--YMAAADNV 273

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
            ++  ++++ + VPE+    ++L++F+  + H A ++DE+G   G++T+ DILE IVG++
Sbjct: 274 HALAPIMKKPLFVPENNSAYQVLEKFKETQSHAAFIVDEYGTFLGMITLNDILEAIVGDM 333

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH----FSDEEVDTIGGLVMQAFG 248
             E  ++DD +  +    ++ V       DF   F         ++E DT+ G ++    
Sbjct: 334 P-ETGQDDDYEIVRREDGSYLVDGQIPFYDFLSKFDKEDWMAEFEQEFDTMAGFILHHQE 392

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           H+P  GE     G+ F++   D+ RI +V V+ P++
Sbjct: 393 HIPKIGEKFAWRGFTFEIVDMDAHRIDKVLVEAPEE 428


>UniRef50_C4ZBH2 Hemolysin n=1 Tax=Eubacterium rectale ATCC 33656 RepID=C4ZBH2_EUBR3
          Length = 303

 Score =  276 bits (707), Expect = 6e-73,   Method: Composition-based stats.
 Identities = 77/274 (28%), Positives = 145/274 (52%), Gaps = 9/274 (3%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           L  +   +    +E+++++R+  +   I     +++  V +  D+ V+DIM  R  +++L
Sbjct: 33  LDGILGNDDVTEEEIISMVREGHEQGTILASEAELIHNVFEFDDKEVKDIMTHRKNIVSL 92

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA----EAFSMDKV 138
             + +  + ++ II++  SRFPV   D D I G+L  KD   F   +         +D +
Sbjct: 93  DGSMSFIDAIEFIIDTGKSRFPVYENDVDSIIGVLHIKDAFTFFEKNEVYRSSIKDIDGL 152

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R    +PE+  ++ + K+ +S++ H+A+V+DE+G +SGL+ +EDILE +VG IEDE+DE
Sbjct: 153 IRPVDFIPETVNINDLFKKMQSKKSHLAMVVDEYGQISGLIAMEDILEELVGNIEDEHDE 212

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETID 258
           E++   R+    T+ +  +    D  EA      D+  +T+ G ++     +P  G+   
Sbjct: 213 EENY-IRKNDDETFIMDGMTEFSDVKEALSLPVDDDAYETLNGFIISLSDKIPEEGDKTV 271

Query: 259 ID--GYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           I   GY+F V   + + I QV +K    +P+ K 
Sbjct: 272 ISAYGYRFSVMSVEDKVIKQVMIKKL--APEEKK 303


>UniRef50_C9MVS3 CBS domain protein n=3 Tax=Fusobacteriaceae RepID=C9MVS3_9FUSO
          Length = 450

 Score =  276 bits (706), Expect = 8e-73,   Method: Composition-based stats.
 Identities = 79/262 (30%), Positives = 156/262 (59%), Gaps = 5/262 (1%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
           E  +++EL +L+    ++ +I+E  ++M+E +++  ++  R+IMIPR+++  + +N ++ 
Sbjct: 178 EKVSKEELRSLVEVGKEHGVINETEQEMIENIIEFDEKIAREIMIPRTKVFLIDKNISIH 237

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDL-LPFMRSDAEAFSMDKVLRQAVVVPES 148
           E  +      +SR PV   + D+I G+L+ KDL +   +   +   +  +L++A  VPE+
Sbjct: 238 ELFENKEIGKYSRIPVYENEADNIVGVLLTKDLMMEAYKKGFDNIKVADLLQEAYFVPET 297

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K V+ +  E + ++ H+ I+IDE+GG SG+VT+ED++E ++G I DE+D+ED +  RQLS
Sbjct: 298 KNVNELFNEMQLEKKHITILIDEYGGFSGIVTLEDLIEEVMGNIADEFDDED-LSIRQLS 356

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETID---IDGYQFK 265
           R+ + +    S+ D N+ F      +  DT+ G++++  G++P   E I+   I+G  FK
Sbjct: 357 RNKYLISGEVSLNDLNDNFNFELESKYYDTLSGILIENLGYIPEDNENIEPITINGVVFK 416

Query: 266 VAMADSRRIIQVHVKIPDDSPQ 287
                +++I +V +    D  +
Sbjct: 417 PQRVRNKKIEKVVMTFDKDKTE 438


>UniRef50_C2BV08 HCC HlyC/CorC family transporter n=3 Tax=Mobiluncus
           RepID=C2BV08_9ACTO
          Length = 426

 Score =  276 bits (706), Expect = 8e-73,   Method: Composition-based stats.
 Identities = 93/291 (31%), Positives = 163/291 (56%), Gaps = 13/291 (4%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKN--------RDELLALIRDSGQNDLIDEDTRDMLEGVM 62
           T  N    F +LLS       +          ++L  ++   G+ D I++  R+M+  V 
Sbjct: 137 TAWNAGKPFGMLLSIARGPSSQTDQEARDEVAEDLREMVDQMGEPDTIEDADREMIWSVF 196

Query: 63  DIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL 122
           ++    VR++M+PR  M+T++  +TLD+ L + + S++SR PVI ED D I GIL  KD+
Sbjct: 197 EMGRTLVREVMVPRVDMVTIESEKTLDKALTLFVRSSYSRVPVIGEDADDIRGILYLKDV 256

Query: 123 LPFMRSDA--EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           L  + SD      + ++ +R+A  +PE   VD  L++ +   YHMA+++DE+G ++GLVT
Sbjct: 257 LRRVNSDPAARQMTAEQAMREAKFIPEMNLVDDTLRDMQQNSYHMAVLVDEYGLIAGLVT 316

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           +ED++E ++GE+ DE+D  +  +       +W V A   + D N+  GT   DE+VDT+G
Sbjct: 317 LEDLVEEVIGEVSDEHDHAEK-EPELQPDGSWIVPARLPLVDLNDLLGTEIDDEDVDTVG 375

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRR--IIQVHVKIPDDSPQPK 289
           GL+ +A G +P  G +  ++G +     A+ RR  +  + V++   +P  +
Sbjct: 376 GLLTKAVGVVPLVGASATVEGLELCAVEAEGRRRQVSAISVRLVPPAPDEE 426


>UniRef50_A9BXY0 CBS domain containing protein n=17 Tax=cellular organisms
           RepID=A9BXY0_DELAS
          Length = 307

 Score =  275 bits (705), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 114/292 (39%), Positives = 167/292 (57%), Gaps = 8/292 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           +SD +   S    +K+ F    +++  H  P + DEL+  + D+  N +I  ++R MLE 
Sbjct: 15  VSDPHPARSSEKESKRSFLQK-VAEFIHPAPDSPDELIETLADAEDNQVIGPESRVMLER 73

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V+ +AD    D+M+   +M  +  +   DE L  +I +AHSRFPV   ++++I GIL+AK
Sbjct: 74  VIRMADMTAGDVMVAAPRMDLVNIDAPFDELLHQVITTAHSRFPVYQGERENIIGILLAK 133

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL   RS     ++  +LR A  VPESK ++ +L+EFR  R H+A+VIDEFG V+GLVT
Sbjct: 134 DLLKLQRSP--DLNIRALLRPAAFVPESKGLNDLLREFRGNRNHLAVVIDEFGRVAGLVT 191

Query: 181 IEDILELIVGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF----SDEE 235
           IED+LE IVGEIEDE+D  ED+ D   L+ +++ V    +IE  NE F         D+E
Sbjct: 192 IEDVLEEIVGEIEDEFDIPEDEGDIFALADNSYRVAGDTTIEHVNETFEVALHARDPDDE 251

Query: 236 VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            DTIGGL+    GH+P RGE I + G +F V       +    V     +  
Sbjct: 252 FDTIGGLIAHEMGHVPKRGEQIHLAGLEFTVLHTKGGAVRWFKVVRDPAADS 303


>UniRef50_A7VIV6 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VIV6_9CLOT
          Length = 268

 Score =  275 bits (704), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 77/269 (28%), Positives = 147/269 (54%), Gaps = 5/269 (1%)

Query: 21  LLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI 80
            L +     E K  +E+++++ +  +  LI +D  +M+  + + +++ VRD+M PRS ++
Sbjct: 2   KLFNNRKADEEKVEEEIISMVNEGNEQGLIHDDEVEMITNIFEFSEKEVRDVMTPRSDVV 61

Query: 81  TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLR 140
            + ++ T+DE + +++E+ +SR+PV  +D D+I GIL  KD +     D    ++++++ 
Sbjct: 62  GIDKHTTMDETIKIMLENNYSRYPVFDDDLDNIVGILYFKDFVKAYLQDKNQ-TIEQIMV 120

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
           +   V  +K +  + K  + ++ HM IV+DE+G   G++ +EDILE IVG I    + +D
Sbjct: 121 EPTFVHPTKNISELFKRMQKEKIHMVIVVDEYGQTEGIIAMEDILEEIVGNIF--DEYDD 178

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET--ID 258
           D D   L+ H + V   A +++ +E  G  F DE+  T+ G ++   G LP   E   I 
Sbjct: 179 DEDDIALAGHGYIVGGRAELDELSEHLGIEFPDEDFQTLNGFMLYELGRLPYENEKIDIT 238

Query: 259 IDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             GY F+      + I +V +   ++  Q
Sbjct: 239 YKGYNFETIGIKDKMIDKVRITKVENENQ 267


>UniRef50_A7VVN2 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VVN2_9CLOT
          Length = 431

 Score =  275 bits (704), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 70/265 (26%), Positives = 135/265 (50%), Gaps = 7/265 (2%)

Query: 30  EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLD 89
                 EL  ++       ++++   ++++  ++  ++ V++++ PR  M TL     L 
Sbjct: 162 PIVTEQELKFIVESIEDEGVLEKQESELVQHALEFDEKTVQEVLTPRVDMTTLDIEDDLQ 221

Query: 90  ECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESK 149
             + +++    SR PV     D I GIL  KDLL  +    +A  +  +++ A  V ++K
Sbjct: 222 TNIGLVLTERFSRIPVCRGTSDRIIGILHTKDLLEALVRG-DAIDLASMVQPAFFVYKTK 280

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
           ++  +L +F+  + H+AIV D++GG  G+VT+ED+LE +VG+I DE DEE   DF ++  
Sbjct: 281 KLSSLLADFKRNKTHVAIVTDDYGGTVGMVTMEDLLEELVGDIWDE-DEEIIRDFVRIDS 339

Query: 210 HTWTVRALASIEDFNEAFGTHFS--DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
             + +    +I +  +     FS  +    + GG  ++A GH+P  GE          + 
Sbjct: 340 QHFLISGDLTIRELFDHLDLPFSNLESNHTSCGGWALEALGHIPQAGEAFQFKNMTLTIQ 399

Query: 268 MADSRRIIQVHVKIPDDSPQPKLDE 292
             D +R+ ++ V +   +PQP+ +E
Sbjct: 400 EMDDQRVKKLSVYL---APQPEEEE 421


>UniRef50_D2RTA7 Putative uncharacterized protein n=3 Tax=Haloterrigena turkmenica
           DSM 5511 RepID=D2RTA7_9EURY
          Length = 467

 Score =  275 bits (704), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 89/265 (33%), Positives = 145/265 (54%), Gaps = 8/265 (3%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
             RDE+  +I    +  +++E+  +ML+ +    +  V+++M PR  M  + ++  +DE 
Sbjct: 192 VTRDEIQEMIESGEREGVLEEEEHEMLQRIFRFNNTIVKEVMTPRLDMTAVPKDAGIDEA 251

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDL---LPFMRSDAEAFSMDKVLRQAVVVPES 148
           ++  I+S H+R PV     D++ G++  +DL   L +  ++A+   ++ +++  + VPES
Sbjct: 252 IETCIQSGHARVPVYEGSLDNVLGVVHIRDLVRDLNYGETEADDLELEDLIQPTLHVPES 311

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K VD +L E R  R HMAIVIDEFG   GLVT+ED++E IVGEI    ++E      QL 
Sbjct: 312 KNVDELLTEMRENRMHMAIVIDEFGTTEGLVTVEDMIEEIVGEILKSGEDEP---IEQLD 368

Query: 209 RHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
             T  VR   +IED NEA      + EE +TI G +    G L   GE I  DG +  V 
Sbjct: 369 DRTVIVRGEVNIEDVNEALEIDLPEGEEFETIAGFIFNRAGRLVEEGEEITYDGVRITVE 428

Query: 268 MADSRRIIQVHVKIPDDSPQPKLDE 292
             ++ RI++  ++  +  P   L+E
Sbjct: 429 TVENTRIMKARLRKLEQ-PTESLEE 452


>UniRef50_C4G6D4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G6D4_ABIDE
          Length = 395

 Score =  274 bits (703), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 88/275 (32%), Positives = 148/275 (53%), Gaps = 7/275 (2%)

Query: 17  GFFSLLLSQLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
              S  + ++F  +P+        +ELL  +  S +  +I+ + ++M+  V+D  D   +
Sbjct: 107 NIISNGILKIFGIDPEENTSGITENELLTYVEVSHEEGIIENEEKEMITNVVDFGDSLAK 166

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           D+M+PR  M T+  + + DE L    E  +SR PV  E+ D+I GI+  KD+  F + D 
Sbjct: 167 DVMVPRVDMYTISDDISYDELLLAFEEDKYSRLPVYRENVDNIIGIVYLKDV-AFYKGDK 225

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           + F +  +LR A    E K+   +L E R     M IV+DE+G   GL+T+ED+LE IVG
Sbjct: 226 KDFKLGSILRPANFTYEFKKTSELLIEMRKSSLSMCIVLDEYGSAVGLITLEDLLEEIVG 285

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           +I DEYD ++  D  +L +  + V     ++DFN+ FGT +  ++ D+I G +++ F  L
Sbjct: 286 DIRDEYDVDEVDDIVRLDQDEFMVLGSTRLDDFNDFFGTEYISDDYDSIAGKLIELFERL 345

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           P +G+ I      F +   D RRI ++ V+    +
Sbjct: 346 PEKGDAITDGSLSFLIESIDHRRIEKIKVRKLPST 380


>UniRef50_Q0VN63 Metal ion transporter n=15 Tax=Gammaproteobacteria
           RepID=Q0VN63_ALCBS
          Length = 295

 Score =  274 bits (703), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 142/287 (49%), Positives = 193/287 (67%), Gaps = 8/287 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MSDD S +  +    + +    + Q F   P +R+ELL L+R      +ID DT  ++EG
Sbjct: 1   MSDDFSDNGTS----RSWLER-VGQFFSPTPGDRNELLELMRSMRDTHIIDGDTLGIIEG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            + +AD +VR+IMIPRSQM+++K +      L  II+ AHSRFPV+ +D D + GIL+AK
Sbjct: 56  AICVADMQVREIMIPRSQMVSIKASSDPRGFLPTIIDCAHSRFPVLGDDPDEVIGILLAK 115

Query: 121 DLLPFMRSDA--EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           DLLP +   A  E F++   +R A+VVPESKR+D +L+EFR  R HMAIV++E+GGV+GL
Sbjct: 116 DLLPLILDPARMERFAIKDHIRSAMVVPESKRLDSLLREFRISRNHMAIVVNEYGGVAGL 175

Query: 179 VTIEDILELIVGEIEDEYDEEDDI-DFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           VTIED+LE IVGEIEDE+D E+D    + L ++ +TV+AL  I+DFNE F   FS+EE D
Sbjct: 176 VTIEDVLEQIVGEIEDEHDIEEDDYLIKDLDKNEYTVKALTPIDDFNEHFHCQFSNEEFD 235

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           TIGGLVMQ FG LP R E+I +DG++  V  AD R I  + V  P D
Sbjct: 236 TIGGLVMQKFGRLPGRDESITLDGFRVTVLSADGRTIRLLRVTPPGD 282


>UniRef50_B1XKG2 CBS domain protein n=2 Tax=Chroococcales RepID=B1XKG2_SYNP2
          Length = 479

 Score =  274 bits (703), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 68/298 (22%), Positives = 135/298 (45%), Gaps = 27/298 (9%)

Query: 21  LLLSQLFHGEPK---------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
            LL +L    P            +EL  +I    ++  ++ + R++L  V++  D    +
Sbjct: 170 RLLLRLGGIAPIQQGLWYDRLTPEELQLIITTEQESMGLEAEERELLSNVIEFGDVVAEE 229

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM PR+++  +    TL + L  + ++ HS +PV  E  D I G +  +D    + +   
Sbjct: 230 IMTPRTKIHAIANGATLGKLLQKVSQTNHSAYPVYGESIDDIVGFVRFRDFAKPLAAGGM 289

Query: 132 AFS--MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
             +  +++ ++    V E   +  +L + +  +  M +V+DEFGG +GLVT++DI+  I+
Sbjct: 290 NLNTAINRWVKPIPFVAEGTPIADLLPKMQRTKQPMVMVVDEFGGTAGLVTLKDIINEII 349

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFG 248
           G+  D +     + F+ L R T+ V A   +E+ N+         ++  T+ G ++  + 
Sbjct: 350 GDELDSH-PNAPLHFKALDRQTFLVDAQIDLEELNDLLNVELPYTDDYQTLSGFLLYQWQ 408

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVK--------------IPDDSPQPKLDE 292
            +P  GE    +  +F+V   D  R+ QV +                P+    P ++E
Sbjct: 409 KIPETGEVFHFEDLKFQVMGIDGPRLQQVKITRDPSDIEAIAEFDFPPEPEDHPDMEE 466


>UniRef50_C7RN87 Putative uncharacterized protein n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RN87_9PROT
          Length = 480

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 80/280 (28%), Positives = 140/280 (50%), Gaps = 14/280 (5%)

Query: 14  NKKGFFSLLLSQLFHGEPKNR-----DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
           +  G   +   +   G  ++      +E+  ++  S ++  +D +   M+ GV  + +  
Sbjct: 170 SSNGLLWIFGQKDLRGHGESHFTMSVEEIRMILSASEKDGTLDPEETQMIRGVFKLDEHT 229

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR- 127
           VR+ M+PR+++  L +  TL + L V  +  H+RFPV  +  D I G++  K+LL  M  
Sbjct: 230 VREAMVPRTRIRALTQEDTLADALRVFRDVPHARFPVCDKSLDRITGVVAIKELLTVMAE 289

Query: 128 ------SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
                  +     + +  +   +VP SK +  +LKEF+  R  MAIVIDE+GG  G++T+
Sbjct: 290 SSGQTLEEVSRRPVGEFAQAPFIVPNSKSLSDLLKEFKHTRQQMAIVIDEYGGTEGIITL 349

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIG 240
           EDILE IVGE EDE+  +     ++L    + + A   + D        F  D++  T+ 
Sbjct: 350 EDILEEIVGEYEDEFTRQ-ARRVKKLVGSQYEIDASMRVSDLETLIDFPFPTDDDYVTLA 408

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
           GL  +  G +P  G+T+ ++G Q  V   D+ RI  +  +
Sbjct: 409 GLFYKKLGSVPKVGDTVKLEGGQLTVLEMDNHRITLLRFE 448


>UniRef50_A7HZ85 CBS domain containing protein n=1 Tax=Parvibaculum lavamentivorans
           DS-1 RepID=A7HZ85_PARL1
          Length = 319

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 91/283 (32%), Positives = 152/283 (53%), Gaps = 12/283 (4%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRDSGQ-NDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           G+   LL    +G+   R+ L  +I +    +  +  + R ML  ++   + RV D+M+P
Sbjct: 27  GWLRALLGLNGNGDGSLRESLEEVIEEHEDMHRSLTAEERHMLVNILKFGELRVDDVMVP 86

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE---- 131
           R+ +I ++ +  L+ECL +   S+HSR P+  E  D   G++  KD+L ++    E    
Sbjct: 87  RADVIGVEESCPLEECLRLFHVSSHSRMPIYRETLDDPIGMVHLKDVLAWLAPQEEEAPP 146

Query: 132 --AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
             AFS+  + R  + VP S     +L + ++ R H+A+VIDE+GG  GLV+IED++E IV
Sbjct: 147 RPAFSLRSIRRNILFVPPSMPALDLLVKMQATRIHLALVIDEYGGTDGLVSIEDLVEEIV 206

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF----SDEEVDTIGGLVMQ 245
           GEIEDE+D ++     +    T    A   IED  +  G        +++VDT+ GLV  
Sbjct: 207 GEIEDEHDTDEGPALVRREDGTIDADARCPIEDLEDMIGLRLVEEEHEDDVDTLAGLVFS 266

Query: 246 AFGHLPARGETIDID-GYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             G +P RGE +    G +F+V  AD+RRI ++ + +   + +
Sbjct: 267 LLGRVPLRGELVRHPAGLEFEVKDADARRIKRMRIHLLTAAEK 309


>UniRef50_O07589 UPF0053 protein yhdT n=119 Tax=Bacillales RepID=YHDT_BACSU
          Length = 461

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 85/257 (33%), Positives = 139/257 (54%), Gaps = 6/257 (2%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           H    + +EL  L+ +S +N  I+      +  + +  ++  ++IMIPR +M  +    T
Sbjct: 176 HDGSHSEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAKEIMIPRKEMAAVSTEMT 235

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAK----DLLPFMRSDAEAFSMDKVLRQAV 143
           + E L+V+++  ++R+PV   DKD + G++  K    DLL     +    ++   +R  +
Sbjct: 236 MAEMLEVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLFMTEEERMKMTIHPYVRPVI 295

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
            V E+  V  +L + + +R HMAI+ DE+GG SGLVT EDILE IVGEI DE+DE++   
Sbjct: 296 EVIETIPVHDLLIKMQRERIHMAILSDEYGGTSGLVTTEDILEEIVGEIRDEFDEDEQPL 355

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
            ++L    + +     I+  N   G     E+VDTIGGL+++    +   GE+I I  Y 
Sbjct: 356 IQKLGDGHYVMDGKVRIDQVNSLLGASI-QEDVDTIGGLILKENIDI-EAGESIRIGSYT 413

Query: 264 FKVAMADSRRIIQVHVK 280
            KV   D R I Q+ +K
Sbjct: 414 IKVLKMDGRLIKQIDIK 430


>UniRef50_UPI0001B44AE5 CBS domain protein n=1 Tax=Listeria monocytogenes FSL N1-017
           RepID=UPI0001B44AE5
          Length = 396

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 80/255 (31%), Positives = 136/255 (53%), Gaps = 4/255 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
            E   R+E+  LI    ++ +I+ +   ML GV ++ ++  R++M+PR+    +      
Sbjct: 131 NEKMTREEMQLLIETGRRDGVIEVEELQMLRGVFEMDNKYAREVMVPRTDAFMVDAEIES 190

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR-SDAEAFSMDKVLRQAVVVPE 147
           +E  D ++    SR PV + D+D + GIL  KD     R S  E   +  +++ A    E
Sbjct: 191 EELCDALLSENFSRVPVYTGDQDSVLGILHMKDFFAEARKSGFENIDVKALVKDAYFAQE 250

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  +D +LK  +  R  MAI++DE+GGV+G+VT+ED+LE IVGEI+DE D   D + +++
Sbjct: 251 TMFIDDLLKNMQRTRNQMAILMDEYGGVAGIVTVEDLLEEIVGEIDDENDVFSD-EVKKI 309

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE--TIDIDGYQFK 265
              T+ V    S++DFNE F        VDT+ G V+   G +P   +   ++    +F 
Sbjct: 310 DETTFIVEGRMSLDDFNEMFHVELPSRGVDTVAGFVLTLTGTIPEEDDKVVVEYGTLRFT 369

Query: 266 VAMADSRRIIQVHVK 280
           V   +  R++ V V+
Sbjct: 370 VEEMNDARLVSVRVE 384


>UniRef50_Q0C626 CBS/transporter domain protein n=7 Tax=Alphaproteobacteria
           RepID=Q0C626_HYPNA
          Length = 424

 Score =  274 bits (702), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 85/279 (30%), Positives = 131/279 (46%), Gaps = 6/279 (2%)

Query: 16  KGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
            G   L+            +E+   I        +D++    L G +D+ D  V D+MI 
Sbjct: 149 NGVLRLVGVGAAASPLSAEEEIRGAIDLHAAEGAVDKENHLRLVGALDLKDLTVEDVMIH 208

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF---MRSDAEA 132
           R  +  L  +    + +   + S H+R P+   +K+ I GIL AKDLL     +  D   
Sbjct: 209 RKNIYMLDADLEPRQLIMKALSSPHTRLPLYRGEKEEIIGILHAKDLLRAALPLGGDVSK 268

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +D +LR+   VPE+  V   L +F ++  H A+VIDE+G + GL+T+EDILE IVG I
Sbjct: 269 LDLDSILRKPWFVPETTPVQEQLNQFLARGQHFALVIDEYGELQGLITLEDILEEIVGAI 328

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DE+D +     R     +  V     I D N A G    DEE  T+ GLV+     +P 
Sbjct: 329 HDEHDVQIQ-GVRPQPDGSVNVDGWVPIRDLNRATGWDLPDEEAVTVAGLVIHEAQTIPE 387

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
            G++    GY+F V      ++  V+V     +P  ++D
Sbjct: 388 PGQSFVFHGYRFNVLRRQRNQVTGVNVSK--AAPVAEVD 424


>UniRef50_D2NSB8 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NSB8_9MICC
          Length = 444

 Score =  274 bits (702), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 66/263 (25%), Positives = 126/263 (47%), Gaps = 7/263 (2%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
           +  +EL +++R S +   +D D    ++  +  ++    ++M PR Q+  L+    + E 
Sbjct: 179 RTPEELSSMVRRSAEEGTLDSDAARFVDRTLRFSELTASEVMTPRGQVAMLEDTAPVAEV 238

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           + +   + HSRFP+   D D+I G++  K  +       E      +    + VPE+  +
Sbjct: 239 IKLARSTGHSRFPLYKGDHDNIVGVVHVKKAVGVPPEVRETLEAGALAEDVLQVPETLHL 298

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D +L + R     +A+V+DE+GG +G+ T+ED++E IVGE+ DE+D        +     
Sbjct: 299 DALLTQLRQGALQLAVVLDEYGGTAGIATLEDLVEEIVGEVSDEHDRGRTERPLRYGNGD 358

Query: 212 WTVRALASIEDFNEAF-GTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
           W    L   ++ N    G    +  E +T+GG +M+  G +P  G+++ + G   +V   
Sbjct: 359 WVFSGLRRPDEINALIPGLEVEESPEYETVGGFMMERLGRIPEVGDSVPVPGGTLRVDTL 418

Query: 270 DSRRIIQVHVKIPDDSPQPKLDE 292
           + RR+ ++        P P   E
Sbjct: 419 EGRRVDRIRFT-----PAPSAQE 436


>UniRef50_B8GZ20 Magnesium and cobalt efflux protein corC-like protein n=5
           Tax=Caulobacteraceae RepID=B8GZ20_CAUCN
          Length = 437

 Score =  274 bits (702), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 77/270 (28%), Positives = 136/270 (50%), Gaps = 4/270 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      L+  +         +E+ A++ +     LI+ + R M++ V+ + D+ VR  M
Sbjct: 160 STAAVLRLMGVRDERNTSVTSEEVEAVLAEGADAGLIEPEERSMIQEVLRLGDRPVRVAM 219

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPV-ISEDKDHIEGILMAKDLLPFMRSDAEA 132
            PR  +  +      +  L  I  SAHSR  V    D D   G+L+ KDLL    S  E 
Sbjct: 220 TPRRDLFWVSLADDTETVLKEIRASAHSRIVVATEGDLDGDVGVLLKKDLLDACLSG-EP 278

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +   ++Q + +PE+  + + L+ F+S   HMA+V+DEFG + G +T  D+LE+I G+ 
Sbjct: 279 LDLKAHVQQPLAIPETMSLLKALQLFKSTSLHMALVVDEFGSLQGAITPLDLLEMIAGDF 338

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLP 251
            +++D+++    R+     W + A   I++ N+  G +F  D    T+ GL++   G LP
Sbjct: 339 PEDHDDDEKRIIRR-EDGGWLIDARLDIQELNDHLGENFEADGGYHTVAGLILDRLGRLP 397

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
             GE ++I G+  ++   D  RI +V +K 
Sbjct: 398 TEGEHVEIGGFDLEIVDMDGSRIDKVILKP 427


>UniRef50_A9U7Q9 Predicted protein (Fragment) n=1 Tax=Physcomitrella patens subsp.
           patens RepID=A9U7Q9_PHYPA
          Length = 278

 Score =  274 bits (701), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 73/260 (28%), Positives = 140/260 (53%), Gaps = 3/260 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
            +  + +EL  L+ +S ++  I+++    +  +    +   +DIM+PR+ M+ L   ++ 
Sbjct: 3   SDAHSEEELRILLSESLESGQINKNEYSFMNRIFTFDELLAKDIMVPRTDMVCLDATKSR 62

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
           +E L +I +  ++RFPVI ++KD+I G++  K L      +     +  ++R  + V E+
Sbjct: 63  EENLRIIRQEQYTRFPVIRQNKDNIIGVINTKALF-LAPDNQAGAPLASLVRPVMTVSEN 121

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             +  +L + + +R H+A++IDE+GG SG+VTIEDILE IVG+I DE+D E++ +  +++
Sbjct: 122 IPLPALLTKMQKERTHIAVLIDEYGGTSGMVTIEDILEEIVGDIRDEFDAEEEQEITEVA 181

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
            +   V    S+   N+       +E+ DTIGG +      +   G  +     QF V  
Sbjct: 182 ANHLIVDGKVSVSLINDWLDAQLEEEDADTIGGWIYGQNLDI-EVGTQLVYGDLQFTVLE 240

Query: 269 ADSRRIIQVHVKIPDDSPQP 288
            +  RI ++ ++   + P P
Sbjct: 241 REDSRIRKIDIEKL-EPPAP 259


>UniRef50_A9NG07 Membrane-anchored CBS-domain containing protein n=1
           Tax=Acholeplasma laidlawii PG-8A RepID=A9NG07_ACHLI
          Length = 449

 Score =  274 bits (701), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 75/279 (26%), Positives = 142/279 (50%), Gaps = 11/279 (3%)

Query: 22  LLSQLFHGEPKNRDE------LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           L+ +LF   P++ D+      L+  +  S     ID    +M++ + +     V ++M  
Sbjct: 165 LIIRLFGINPQDDDDTLSEEELILELNASESKGFIDSSENEMIQNIFEFDSTTVEEVMTH 224

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM--RSDAEAF 133
           R+++  +  N T DE +  +    ++RFPV  E  D I G L  KDLL ++    D   F
Sbjct: 225 RTEVSAINVNSTRDELVKFVTNEKYTRFPVYEETLDKIVGTLHVKDLLKYLSEHEDKNEF 284

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + ++LR  + VP+SK    + +E +  + H+AIVIDE+GG +G++T ED++E I+G I 
Sbjct: 285 DIHEILRDPLFVPQSKNTRALFREMKLTKTHIAIVIDEYGGTAGIITFEDLIEEILGNI- 343

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
            +  +ED+ + + +S   + +  L  ++D  +        E+ DT+ G ++   G  P  
Sbjct: 344 SDEYDEDEEEIQAISEDRYEIDGLIDLDDVEDLIHAGLPIEDYDTLSGFLLGQLGRFPEA 403

Query: 254 GET--IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
            E+  +    Y+F+V   + + I +V V   ++ P  ++
Sbjct: 404 DESIVVVYGHYRFEVLSYEDKIIERVLVTRIEEEPIEEV 442


>UniRef50_D2NT77 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NT77_9MICC
          Length = 488

 Score =  274 bits (701), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 90/280 (32%), Positives = 150/280 (53%), Gaps = 14/280 (5%)

Query: 7   HSSDTISNKKGFFSLLLSQLFHGEPK-------NRDELLALIRDSGQNDLIDEDTRDMLE 59
           + S  +S   G    L  +L             + +EL   +  +   + I++D   M++
Sbjct: 136 YLSVLLSPATGLLDKLSVRLAPERSAEAPVGVFDEEELREFLDRASDAETIEDDEAQMVQ 195

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
            V ++ D R+R +M+PR+ M+T  R+  L E L + + S +SR PVI +  D I G+L  
Sbjct: 196 SVFEMDDTRIRSLMVPRTDMLTASRDTPLREALSLFLRSGYSRMPVIGDSSDEILGVLYL 255

Query: 120 KDLLPFMRSDAEA------FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFG 173
           KD +       EA       ++ +++R A   PESKR   +L+E + +  H+AI++DE+G
Sbjct: 256 KDAMRAFILHGEAPEGTALPTVVELMRPARFEPESKRAMDLLREMQRESTHVAIIVDEYG 315

Query: 174 GVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD 233
           G +GL+T+ED++E +VG+I DEYD E   ++      T+ + A   I++  E FG    D
Sbjct: 316 GTAGLITLEDLIEELVGDISDEYDHERP-EYTLNDDGTFRLSARLGIDELGEIFGRELDD 374

Query: 234 EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
           E+VDT+GGL+ +  G +P  G  I+IDG   +   +  RR
Sbjct: 375 EDVDTVGGLLAKHLGMVPIVGSEIEIDGIHIRAIGSSGRR 414


>UniRef50_C1F1N4 CBS/transporter domain protein n=1 Tax=Acidobacterium capsulatum
           ATCC 51196 RepID=C1F1N4_ACIC5
          Length = 457

 Score =  274 bits (701), Expect = 4e-72,   Method: Composition-based stats.
 Identities = 76/268 (28%), Positives = 136/268 (50%), Gaps = 15/268 (5%)

Query: 27  FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQ 86
             G   + +EL+ +   + +  ++ E    ++   +++ +   R+IM PR QM  L  + 
Sbjct: 176 HQGGVHSSEELMLMATAARRMGVLPEFEETLIHRSLELDELLTREIMTPRQQMFALPFDL 235

Query: 87  TLDECLDVIIESAHSRFPVISEDKDH--IEGILMAKDLLPFMRSDAEAFS---------- 134
            +++    I+   HSR PV    + H  I G++ AKD+   M   A A +          
Sbjct: 236 PIEQASARIVAEMHSRIPVYDPARGHEFIVGVVYAKDIARLMHFRASAQTRFSSEPFSGM 295

Query: 135 -MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + +V+R+ +VVPE+K V  +L+EF+ +R H+AIV+DE+G   GLVT+ED +E ++GE+E
Sbjct: 296 LLRQVMREVLVVPETKPVLDLLREFQQRRRHLAIVVDEYGSTIGLVTVEDAIEQLIGEVE 355

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPA 252
           DE+D        + S     +    ++ D           +  V+T+ G V+   G +P 
Sbjct: 356 DEFDLAPPSLLARTS-GELVLDGSVTLRDLETQMHWDLPREGGVETLAGFVLTQLGKIPE 414

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVK 280
           +GE+I  DG +  V   +  RI ++ V+
Sbjct: 415 QGESIVYDGRRLTVMEMEGNRISRIRVQ 442


>UniRef50_UPI0001973384 hypothetical protein ClM62_01605 n=1 Tax=Clostridium sp. M62/1
           RepID=UPI0001973384
          Length = 470

 Score =  273 bits (700), Expect = 5e-72,   Method: Composition-based stats.
 Identities = 84/253 (33%), Positives = 134/253 (52%), Gaps = 4/253 (1%)

Query: 36  ELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVI 95
           ++  +I    +   I ED  + ++ V D  D  +   M   S ++ L  + +  E L +I
Sbjct: 188 DIRMMIDLGKEKGTIAEDENEWIQNVFDFRDTSILSAMTRESDIVNLFEDSSEQEILKII 247

Query: 96  IESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRML 155
            ES  SR PV ++D + ++GIL  ++ L  + +  +  S+ ++L QA  VPES   D + 
Sbjct: 248 RESGLSRLPVYTKDHEDVKGILYTREYLLNLTA-KQPKSLSQLLHQAYFVPESIHADDLF 306

Query: 156 KEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVR 215
           ++ ++++ HMAIV+DE+G +SGL+T+ED+LE IVG I DE+D   D +  ++S + W   
Sbjct: 307 RDMQTKKVHMAIVVDEYGNISGLITMEDLLEEIVGSIYDEFDRVIDPEIERISENLWRFP 366

Query: 216 ALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGET--IDIDGYQFKVAMADSR 272
               IED  E       D EE DTIGG+V+     +P  G T  ++I+G          R
Sbjct: 367 GDTLIEDVEEQMDITLPDQEEYDTIGGMVLSCLHTIPKDGTTVDVEINGLSLHAEKIVGR 426

Query: 273 RIIQVHVKIPDDS 285
           RI  V VK  D  
Sbjct: 427 RIESVLVKKLDTE 439


>UniRef50_C1F7E2 CBS/transporter domain protein n=1 Tax=Acidobacterium capsulatum
           ATCC 51196 RepID=C1F7E2_ACIC5
          Length = 425

 Score =  273 bits (700), Expect = 5e-72,   Method: Composition-based stats.
 Identities = 90/275 (32%), Positives = 152/275 (55%), Gaps = 7/275 (2%)

Query: 18  FFSLLLSQLFHGEPKNRDE---LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           F S+      H E +  DE   + ALI    +  +++E  R+++   ++  D+ VR++M 
Sbjct: 149 FLSIAALAEPHTEARAEDESEAVEALIEAGEEEGILEESDRELIRSAVEFGDKVVREVMT 208

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR Q+  +  + TL++  +++ E+ +SR PV     DHI GI+ A DLL     DA   +
Sbjct: 209 PRPQLFAVPGSLTLEQFTEMLRENPYSRVPVYEGSVDHITGIIFAHDLLQITDEDARTRT 268

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +  + R A  VPESK+V+ +L+E + ++ HM +VIDE+GGV+GLVTIED+LE IVG I D
Sbjct: 269 VASLQRPASFVPESKKVNALLREMQMEKQHMRLVIDEYGGVAGLVTIEDLLEEIVGSITD 328

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS---DEEVDTIGGLVMQAFGHLP 251
           E+++ D     +    +  V     I    E          D +  T+ GLV +  G +P
Sbjct: 329 EHEDHDLAQVVREPSGSLIVPGTLEISTLEELLHEEVEIPQDMDATTVAGLVSELAGRIP 388

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHV-KIPDDS 285
             GE ++  G +F++  +  RRI ++ + ++P+D+
Sbjct: 389 MAGEVVEQLGMRFEILASTDRRIERMRIARLPEDT 423


>UniRef50_C1ZED0 CBS domain-containing protein n=1 Tax=Planctomyces limnophilus DSM
           3776 RepID=C1ZED0_PLALI
          Length = 453

 Score =  273 bits (699), Expect = 5e-72,   Method: Composition-based stats.
 Identities = 62/281 (22%), Positives = 128/281 (45%), Gaps = 5/281 (1%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
            K    +L  +    +  + +++  LI    +  ++ E  + M +  + + ++   +I+ 
Sbjct: 165 TKSVLLILGQKTEIRDSVSVEDIQHLIDAGHEAGILHEAEQQMAQQALKMRERTAAEILR 224

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR  +  +  +   +E L  +  S  SR PV     D I G +  KD+         +  
Sbjct: 225 PRIDIDAIDVDTPPEEVLGAMAMSGFSRVPVCEGSIDRIVGFIYIKDVFLENYLG-RSLD 283

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           + +V+R  + +P++  + ++L+ F+ +R  +AIV+DE+GG  G+VT+ED++E++VG I D
Sbjct: 284 IRRVMRAPLFIPKTLTISKLLELFQKERTQLAIVLDEYGGTEGMVTLEDVMEILVGSIHD 343

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT----HFSDEEVDTIGGLVMQAFGHL 250
           E+  +D+    + +  +    A  ++ +  EA             + TI GLV+      
Sbjct: 344 EHRRDDEQLIVRRADGSLLADAALNLHELQEALEFSKWPEPPPRGIATISGLVVALLKRP 403

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           P  G+ I     + +V   D  RI ++ V         + +
Sbjct: 404 PKIGDIIQWSQLRVEVVDMDGPRIDRLLVSRIVPESSNEAE 444


>UniRef50_B6BWN1 Putative uncharacterized protein n=1 Tax=beta proteobacterium KB13
           RepID=B6BWN1_9PROT
          Length = 280

 Score =  273 bits (699), Expect = 6e-72,   Method: Composition-based stats.
 Identities = 117/268 (43%), Positives = 178/268 (66%), Gaps = 5/268 (1%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           K      LL +L   +PK ++ELL L++ S Q +LID D+  MLEGV+ I+D + RD+MI
Sbjct: 6   KLKIIPKLLKRLI--QPKTKEELLILLQKSYQANLIDSDSLMMLEGVLGISDMQARDVMI 63

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PRSQ+  +  N ++D  +D  + +AHSRFPVI ED +++ GIL+AKDL+    +  +   
Sbjct: 64  PRSQVSFININDSVDVIIDTALHTAHSRFPVIDEDSNNVIGILLAKDLVRL--NKEKDLD 121

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +  +LR  V +PESK+++ +LKEFRS R H+AIV+DE+ G++G++TIED+LE IVGEIED
Sbjct: 122 LRDILRPPVYIPESKKLNVLLKEFRSNRNHIAIVVDEYAGIAGILTIEDVLEQIVGEIED 181

Query: 195 EYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           E+D +E++ +  Q    T+ ++A   +E+FNE F T++   E  T+GGLV+   GHLP +
Sbjct: 182 EFDYDENEDNIIQEETATFRIKASTELEEFNEFFKTNYPINEYQTVGGLVISKLGHLPKK 241

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKI 281
            E I  DG+  +V   DSRR+  +   +
Sbjct: 242 NEPIHFDGFDIEVLRRDSRRLYLLRFSV 269


>UniRef50_B6FYX0 Putative uncharacterized protein n=1 Tax=Clostridium hiranonis DSM
           13275 RepID=B6FYX0_9CLOT
          Length = 446

 Score =  272 bits (698), Expect = 7e-72,   Method: Composition-based stats.
 Identities = 81/261 (31%), Positives = 142/261 (54%), Gaps = 17/261 (6%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           +  ++        I+ D ++ ++ V D +D  VR+IM  +S+++ +  + +L E  + I 
Sbjct: 186 IRMMLEIGNTGGTINSDEKEWIDNVFDFSDSSVREIMTHKSEVVGIYTDDSLMEIEEKIH 245

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRS-------------DAEAFSMDKVLRQAV 143
           E+ +SR+PV  E+ + I+GIL AKD    + +             +    ++   LR+  
Sbjct: 246 ETGYSRYPVYGENDNDIKGILYAKDFFAEVYNCFAKEDDDLGVVVNKNELNIMDNLRKPY 305

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
            +P+S     + K  +    H+AIVI+E+G   GL+T+ED+LE IVG I DEYDE DD D
Sbjct: 306 FIPDSMSSLLLFKNMQKNNTHIAIVINEYGENIGLITMEDLLEEIVGNIYDEYDECDDGD 365

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDID-- 260
             ++S  TW ++   S++D ++ F   F D+ + DTI GL++     +P  GE  +I+  
Sbjct: 366 V-KISETTWKIKGSTSLDDLSDKFDIDFPDDLDYDTISGLILAKIQRIPNDGEKFEIEAF 424

Query: 261 GYQFKVAMADSRRIIQVHVKI 281
           G + KV   ++R+I +V + I
Sbjct: 425 GMKIKVEKVEARKIEEVIITI 445


>UniRef50_C0W0A3 HCC HlyC/CorC family transporter n=1 Tax=Actinomyces coleocanis DSM
           15436 RepID=C0W0A3_9ACTO
          Length = 429

 Score =  272 bits (698), Expect = 7e-72,   Method: Composition-based stats.
 Identities = 85/241 (35%), Positives = 142/241 (58%), Gaps = 3/241 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+  ++ + G+    +E+ R+ML  V ++    VR++M+PR++M+T+    T+DE LD+
Sbjct: 171 EEMREVVDEVGETSGFEEEDREMLRSVFELGYTLVREVMVPRTEMVTIAAETTIDEALDL 230

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFM--RSDAEAFSMDKVLRQAVVVPESKRVD 152
            + S +SR PVI +D D I GI+  KD++  +  R D +   +  V R+   VPE    D
Sbjct: 231 FVTSGYSRIPVIEDDIDDIVGIVYFKDVISRLRRRPDDKQVPVRNVCREPRFVPEVVLAD 290

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
             L++ ++ R H+A+V+DE+GG++GLVTIED+LE IVGE+ DE+D  +     ++S   W
Sbjct: 291 DELRQMQASRVHLALVVDEYGGIAGLVTIEDLLEEIVGELTDEHDR-NVTQPEEISEGVW 349

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V A  S+ +  E  G    DE+VD++GG + +  G +P  G++ + D        A  R
Sbjct: 350 RVPARFSLWELGELLGVELEDEDVDSVGGYLAKLLGKVPLPGDSAETDDIMITAEEAVGR 409

Query: 273 R 273
           R
Sbjct: 410 R 410


>UniRef50_C1DDZ1 Mg/Co transporter-like protein n=7 Tax=Pseudomonadaceae
           RepID=C1DDZ1_AZOVD
          Length = 426

 Score =  272 bits (697), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 76/283 (26%), Positives = 146/283 (51%), Gaps = 11/283 (3%)

Query: 17  GFFSLLLSQLFHGEPK-------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           G+ S  L +L    P+         +EL +++ +SG+   +  + R ML G++D+    V
Sbjct: 147 GWISNGLLRLAGIAPQGKGSASLTSEELRSMLHESGE--TLSPNRRGMLLGILDLERVSV 204

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RS 128
            DIMIPR++++ L  ++T++  ++++  ++H+R PV   D + IEG++  + +   + R+
Sbjct: 205 NDIMIPRNEVVGLDLDETMEAMVELLRSTSHTRLPVFRGDINRIEGVVHMRHIAHLLTRN 264

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
                ++ +  ++   VPE+  +   L +F+ Q+  +AIV+DE+G V G+VT+EDIL  I
Sbjct: 265 RLTKENLREACQEPYFVPENTPLAVQLIQFQQQKRRIAIVVDEYGDVQGIVTLEDILGEI 324

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VGE  +  D +   D R     +  +   A + + N+  G     +   T+ GL+ +A  
Sbjct: 325 VGEFTNR-DHQFAPDIRAQEDGSQIIDGAAHVREVNKTLGWQLPSDGPRTLNGLITEALQ 383

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           ++P  G  + I  Y+ ++      R+  V V   D  P P  +
Sbjct: 384 NIPDCGVCLSIGPYRLEILETSGNRVKNVRVWTADARPSPTHE 426


>UniRef50_D0RQJ3 CBS domain containing protein n=1 Tax=alpha proteobacterium HIMB114
           RepID=D0RQJ3_9RICK
          Length = 281

 Score =  272 bits (696), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 85/270 (31%), Positives = 154/270 (57%), Gaps = 7/270 (2%)

Query: 17  GFFSLLLSQ--LFHGEPKNRDELLALIRDSGQNDL----IDEDTRDMLEGVMDIADQRVR 70
              S L+ +          RD +  +I +    +     +    + +L  ++ I   +  
Sbjct: 8   NIISKLIKKINFLGNNQSLRDSIKDVIDEKSNEESQNIDLSSKEKSILSNILSINKLKAD 67

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           D+MIPR+ ++ + +N +    +D I + +HSR PV  +D D + G++  KD++ F  S+ 
Sbjct: 68  DVMIPRASIVAISQNSSFKNVIDTIDKESHSRMPVFRKDLDDVLGMIHIKDIIKFAGSNY 127

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
             F++ K++R+ + VP +  V  +L + ++ + HMA+VIDE GG  GL+TIED++E IVG
Sbjct: 128 NDFNIKKIMREVLFVPPTMPVMNLLLKMQATKLHMALVIDEHGGTDGLITIEDVIEEIVG 187

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           EIEDE+D++DD +F+++  +T+  +A  +++DFN        +E VDT+GG +      +
Sbjct: 188 EIEDEHDKDDDFNFKKIDSNTFEAKADMTLDDFNHESNLSIVEENVDTLGGYIFSKINRV 247

Query: 251 PARGETIDIDG-YQFKVAMADSRRIIQVHV 279
           P  GE I +D  YQF++  AD R+I ++ +
Sbjct: 248 PYAGEVIKVDNTYQFEIIEADPRKIKKIRI 277


>UniRef50_B2S3N8 Hemolysin n=5 Tax=Spirochaetaceae RepID=B2S3N8_TREPS
          Length = 265

 Score =  272 bits (696), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 81/230 (35%), Positives = 141/230 (61%), Gaps = 2/230 (0%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           ++E+ +DM+ G++D++D  VR++MIPR  +  L+ + + +  ++ + ES HSRFPV  + 
Sbjct: 21  LNEEKQDMIRGIVDLSDTSVREVMIPRIDVDFLELSMSGETLVEKVTESGHSRFPVYEQT 80

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVI 169
            D++ G+L  KDL+       +   ++++LR+   VPESKR+D +L+EF+ +  H+AI +
Sbjct: 81  IDNVVGVLYVKDLIKLF-GRPQEVRLERLLRKPFFVPESKRIDSLLREFKRRHVHIAIAV 139

Query: 170 DEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT 229
           DE+GGVSG+  +EDI+E IVG+I+DE+D E + D   L +  W   A   +ED +E   T
Sbjct: 140 DEYGGVSGIACMEDIIEEIVGDIQDEFDHERE-DIEPLGQGVWLCDARVDLEDLSECLHT 198

Query: 230 HFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
            F  +E  T+GG V   FG +P + E +    + F +   ++ +I  + +
Sbjct: 199 VFPSQEFGTLGGFVFNLFGKIPVKYEKVSWGAFDFIIQDMEAHKINTIKI 248


>UniRef50_C0GM71 CBS domain containing protein n=1 Tax=Desulfonatronospira
           thiodismutans ASO3-1 RepID=C0GM71_9DELT
          Length = 270

 Score =  271 bits (695), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 82/247 (33%), Positives = 150/247 (60%), Gaps = 2/247 (0%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           L  +IR++ +   I  +   ML  ++ + +++  +IM+PR+ ++  + N TL +  + I+
Sbjct: 25  LEEVIREASEEGEIKNEEVRMLLNILRLHEKQAVEIMVPRTDLVCAEENDTLKDVAESIL 84

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLK 156
           +S HSR PV  E+KDHI G++ AKDLL     + +  S++ ++R+   +PE+K V ++L 
Sbjct: 85  QSGHSRLPVYRENKDHIVGLIHAKDLLQHFFENKD-VSVNSLMREPHFMPETKNVRQILM 143

Query: 157 EFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRA 216
           +F++Q+ H+ +V+DE+GG SG+VT+ED+LE IVGEIEDEYD     + + +   T+ V  
Sbjct: 144 DFQNQKIHLGVVLDEYGGTSGIVTLEDVLEEIVGEIEDEYDPPRPQEVQTMDDGTYYVAG 203

Query: 217 LASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ 276
             S+++  +  G     E+V+TIGG +    G +P +GE    + + + V  A+++ I  
Sbjct: 204 RTSLDELAD-IGIKIPTEQVETIGGYISHLAGKVPVKGEEFSDEFFSYVVQEANTKNIQW 262

Query: 277 VHVKIPD 283
           + ++  D
Sbjct: 263 LTIRRLD 269


>UniRef50_C9LYN4 CBS domain protein n=2 Tax=Selenomonas RepID=C9LYN4_9FIRM
          Length = 481

 Score =  271 bits (695), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 80/250 (32%), Positives = 140/250 (56%), Gaps = 2/250 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +E+  L+ +S +   ID+   + ++ V D AD  VR+IMIPR+ M+ L    +L+E 
Sbjct: 195 HTEEEIRVLMEESHRQGFIDKTELEFVDNVFDFADLSVREIMIPRTDMVCLDLEDSLEES 254

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           +++ +E   +R+P+    KD+I G L  KD L  +    E   + K+ R A+VVPE+  V
Sbjct: 255 IEMAMEERLTRYPICDGGKDNIIGFLHIKDFLQTLYKKEEP-DLRKLARHALVVPEAMAV 313

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
            R+L+  + +R  +AIV+DE+GG +G+VTIED++E IVG+I+DE+D +  +   +     
Sbjct: 314 SRLLQTMQQERSQLAIVVDEYGGTAGMVTIEDVIEEIVGDIQDEFDTDRPL-VEKKGACL 372

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           ++V A   +E+  +       +EE+D++GG +     + P  G+       QF V   + 
Sbjct: 373 YSVDAKMLLEELEDILEVAIDEEEIDSVGGWLSAHVDNPPRIGQKAAFGDAQFFVEETEG 432

Query: 272 RRIIQVHVKI 281
            RI +V  ++
Sbjct: 433 VRITRVLCRL 442


>UniRef50_B3QAC3 CBS domain containing protein n=15 Tax=Rhizobiales
           RepID=B3QAC3_RHOPT
          Length = 381

 Score =  271 bits (695), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 93/309 (30%), Positives = 161/309 (52%), Gaps = 33/309 (10%)

Query: 17  GFFSLLLSQLFHGEPKN-RDELLALIRDSGQNDL-IDEDTRDMLEGVMDIADQRVRDIMI 74
            +    +  LF  +P + RD+L  ++  S  +D       R ML  ++ + D+R+ D+M+
Sbjct: 39  SWLIRAIRSLFGWKPGSVRDDLQVVLDTSPPDDTGFSTLERTMLRNILGLHDRRIADVMV 98

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS------ 128
            R+ ++ +K++  L E L +  ++AHSR  V +E  D   GI+  +DL+ FM +      
Sbjct: 99  HRADIVAIKQDIQLGELLSLFQDAAHSRLVVYNETLDDPVGIVHIRDLVAFMTAKAKVPP 158

Query: 129 --------------DAEAFSMD------KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIV 168
                         D  A  +        ++R+ + VP S R   +L + ++ R H+A+V
Sbjct: 159 ATVAKRKKALPAGLDLRAIDLKMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALV 218

Query: 169 IDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG 228
           +DE+GG  GLV+IEDI+E IVGEI+DE+D  +     + +  ++   A AS+ED     G
Sbjct: 219 VDEYGGTDGLVSIEDIVEQIVGEIDDEHDSTEPPSIVRQADGSFIADARASLEDVRAMIG 278

Query: 229 THF----SDEEVDTIGGLVMQAFGHLPARGETIDIDG-YQFKVAMADSRRIIQVHVKIPD 283
             F    + E+V+T+GG ++   G LP RGE I   G ++F+V  AD RR+ ++ +    
Sbjct: 279 DQFVTGEAGEDVETLGGYLVNHVGRLPVRGEVIAGPGTFEFEVLDADPRRVKRLRIGPRK 338

Query: 284 DSPQPKLDE 292
           + P P+  +
Sbjct: 339 ERPAPRTRD 347


>UniRef50_Q2W097 Putative Mg2+ and Co2+ transporter CorB n=1 Tax=Magnetospirillum
           magneticum AMB-1 RepID=Q2W097_MAGSA
          Length = 430

 Score =  271 bits (694), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 74/234 (31%), Positives = 123/234 (52%), Gaps = 4/234 (1%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           ML  ++++ D  V  +M  R  ++T        E L++++ S  SR P+  +D D+I G+
Sbjct: 196 MLRSILELGDVEVEQVMTHRRGVVTADAGLPAAEILELVVSSPFSRVPLWKDDPDNIVGV 255

Query: 117 LMAKDLLPFMR---SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFG 173
           + AKDLL  +R    + +   + ++      +P+S  +   L+ FRS+R H A+V+DE+G
Sbjct: 256 VHAKDLLRAVRALDGELDKLDVVELASPPWFIPDSTTLLEQLQAFRSRREHFALVVDEYG 315

Query: 174 GVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD 233
            + G+VT+EDILE IVG+I DE+D       R  S  ++ V    +I D N  F     D
Sbjct: 316 TLMGVVTLEDILEEIVGDIADEHDVA-VAGVRPQSDGSYIVDGSVTIRDLNREFEWRLPD 374

Query: 234 EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           EE  TI GL++     +P  G+     G++F++A     +I  + V  P  +P 
Sbjct: 375 EEAATIAGLILHEARQIPDVGQVFRFYGFRFEIARRQRNQITSIRVMPPAPAPS 428


>UniRef50_UPI0000510515 magnesium and cobalt efflux protein n=1 Tax=Brevibacterium linens
           BL2 RepID=UPI0000510515
          Length = 442

 Score =  271 bits (694), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 74/249 (29%), Positives = 138/249 (55%), Gaps = 2/249 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
           ++ +EL +L+R S +  ++DE T D+LE  +  +++   D+M PR++M ++ ++ T    
Sbjct: 179 RSPEELTSLVRHSAEEGMLDEQTADLLERTLSFSERTAEDVMTPRTRMSSVVKDTTARAI 238

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           ++   E+  SRFPV  EDKDHI G++  K       ++ +      ++ +   +PE+  +
Sbjct: 239 IEQARETGFSRFPVAGEDKDHIVGVVHVKQAFAVPLANRDDAYAGGLMTEVTEIPETLLL 298

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D +L E R+Q   MA+V+DEFGG +G+VT+ED++E +VGE+ DE+D    +  R     T
Sbjct: 299 DPLLMELRAQGLQMAVVVDEFGGTAGVVTLEDVVEELVGEVADEHDRMR-VAARPARDGT 357

Query: 212 WTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
           W V      ++ +   G    ++ + +T+ G V++  G +P  G+ +  D    +V    
Sbjct: 358 WIVPGQLRPDEVSSTVGLQIPEDSDYETLAGFVLKELGRIPEPGDQVRTDDALIRVERMH 417

Query: 271 SRRIIQVHV 279
            RRI ++ +
Sbjct: 418 GRRIERLRI 426


>UniRef50_B7K5Y6 Putative uncharacterized protein n=6 Tax=Cyanobacteria
           RepID=B7K5Y6_CYAP8
          Length = 463

 Score =  271 bits (694), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 75/263 (28%), Positives = 136/263 (51%), Gaps = 4/263 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +EL  +I   G++  ++   R +L+ + +  +    ++M+PR+Q++ +    T  + 
Sbjct: 191 VTSEELQLIIATEGESTGLEAKERALLKNIFEFGNVAAVEVMVPRTQLVAISEEATFSDL 250

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDL-LPFMRSDAEAF-SMDKVLRQAVVVPESK 149
           L+ + ++ HSR+PV  E  D I G +  KDL  P  R +     S  + L+    V ES 
Sbjct: 251 LEEVTKTGHSRYPVTGESLDDILGFIDFKDLAFPLARGELTPEASFRRWLKPVKFVSESM 310

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
            +D +L   +  +  M IV+DEFGG SGL+TI+D++  I+ + + E +  ++I  + L  
Sbjct: 311 PLDELLSLMQRSQLKMVIVVDEFGGTSGLITIQDLIAEII-DSDLEDNITENIALQMLDE 369

Query: 210 HTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
           HT+ V A  ++ED N          +E  T+GG ++  +  +P  GET+  +  +F V  
Sbjct: 370 HTFLVEAQINLEDLNTVLDLDLPLTDEYQTLGGFLLYQWQKIPHVGETLAYNNLEFTVVA 429

Query: 269 ADSRRIIQVHVKIPDDSPQPKLD 291
           AD  R++Q+ +   +   Q  LD
Sbjct: 430 ADEPRLLQIRLHRQNPPNQNPLD 452


>UniRef50_B4U6L1 CBS domain containing protein n=1 Tax=Hydrogenobaculum sp. Y04AAS1
           RepID=B4U6L1_HYDS0
          Length = 417

 Score =  271 bits (693), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 76/276 (27%), Positives = 141/276 (51%), Gaps = 6/276 (2%)

Query: 12  ISNKKGFFSLLLSQLFHGEPK-NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           ++  K    L   +    E K + + ++ +++         E+   M++ V  + +  VR
Sbjct: 142 VAPVKKILKLFGVENISLEKKFSLEHIVYIMQSPANAQEFSEEETQMIQKVSQMRETIVR 201

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           +IM PR  +  L+  QT+ E ++ I+E  HSR P+  + KD++ G +  KDL P  +   
Sbjct: 202 EIMTPRLDIFMLEATQTVKEVINDILEHEHSRIPIYKDTKDNVVGYIHIKDLTPVYQHKD 261

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           +   +   LR    +PE   +  +L+E +     + +V+DE G +SGL+T  D+LE + G
Sbjct: 262 DTLEI--FLRPIEFIPEVMSIKNLLQEMKKSSSQIMMVVDEHGAISGLITKHDLLEWLAG 319

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGH 249
           ++  E+++E++  F ++S   + V   ASIE+     G   S+  + DT+ G +M   G 
Sbjct: 320 DLPQEWEDENE--FTKMSSDVYIVEGSASIEEVAATVGFELSENYDYDTLSGFIMANMGK 377

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           +P  G+  +  G++F V   D ++I  V +KIP D 
Sbjct: 378 IPKEGDEFEYKGFKFIVDKMDGKKIEHVLIKIPTDK 413


>UniRef50_C4GB29 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
           DSM 14600 RepID=C4GB29_9FIRM
          Length = 290

 Score =  271 bits (693), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 76/276 (27%), Positives = 152/276 (55%), Gaps = 8/276 (2%)

Query: 13  SNKKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           S+K  FFS L  +     E +  ++L++ IR+  +  ++      M+  +   AD+ V+D
Sbjct: 6   SSKNKFFSRLFHRDEALSEDEFEEDLISKIREGHEQGVLSAREVTMIRNIFAFADKDVKD 65

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM  RS ++ +    T+ E ++ +IE+ +SR+PV  ++ D+I G++  KD L ++    +
Sbjct: 66  IMQHRSNIVAIDGESTMQEAVEQMIENHYSRYPVYIKNLDNIIGLVHIKDTLRYVAEGHD 125

Query: 132 ----AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
                  ++ ++R+ + VP++  +D +L + + ++ HM +V DE+G   GL+++ED++E 
Sbjct: 126 MSVKLRDLEYMVRRVIFVPQTHSIDTLLAQMQHRKNHMILVQDEYGQTCGLLSMEDVIEE 185

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           IVG I+DEYD+ED++   +L    + ++    ++   +  G   SDEE +T+ G +++  
Sbjct: 186 IVGNIQDEYDDEDEL-VARLGDGAYMMQGSTPLDTVADTLGIDLSDEEAETLNGFLLEKL 244

Query: 248 GHLPARGETIDI--DGYQFKVAMADSRRIIQVHVKI 281
           G +P   E+ D+   GY F V   +    + V +  
Sbjct: 245 GRIPQDHESFDVTARGYHFHVIDVEHMVALGVRISR 280


>UniRef50_C6D831 Putative uncharacterized protein n=6 Tax=Bacillales
           RepID=C6D831_PAESJ
          Length = 445

 Score =  271 bits (693), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 75/251 (29%), Positives = 140/251 (55%), Gaps = 2/251 (0%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           +  ++ DS Q+  I+      +  +    +   ++IM+PR+ MI L  N ++ E +D+I 
Sbjct: 187 IQIILNDSFQSGKINNTEYGYVSRIFAFDEMLAKEIMVPRTDMICLYTNNSMMENMDIIR 246

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLK 156
           +  ++RFPV +  KD+I G++  K L    + + E F+  K++   + V E   V  +LK
Sbjct: 247 KEQYTRFPVATGSKDNIVGMINTKQLFLEFQENKE-FNFQKLVHPVLAVSEVLPVKTLLK 305

Query: 157 EFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRA 216
             + +R H+A+++DE+GG SG++TIEDILE IVGEI DE+D ++  +  +L+ + + +  
Sbjct: 306 RMQQERVHIAVLMDEYGGTSGMITIEDILEEIVGEIRDEFDTDERKEIEKLADNCYLLDG 365

Query: 217 LASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ 276
             S++  +E  G     E+VDT+GG +   F   P  G+ +  +  +F +      RI +
Sbjct: 366 KVSLDHVSEITGVAIDQEDVDTVGGWLFTEFTD-PKPGKEMHYENLRFIIREVGKHRIKK 424

Query: 277 VHVKIPDDSPQ 287
           V + I +++ +
Sbjct: 425 VELIIEEEADE 435


>UniRef50_C0QYZ5 Hemolysin protein n=2 Tax=Brachyspira RepID=C0QYZ5_BRAHW
          Length = 444

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 77/254 (30%), Positives = 133/254 (52%), Gaps = 6/254 (2%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + +++  +I    +  +I E T +ML GV+D  ++ V +IM PR  M+ ++    ++E +
Sbjct: 162 SMEDITTIIHLGHKEGIIKEYTHEMLTGVIDFRNKTVEEIMTPRVDMVCIEAETDVNEII 221

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLP-FMRSDAEAFSMD----KVLRQAVVVPE 147
            + +ES  SRFPV  E  DHI GI   + L   +++   +   +       +     VPE
Sbjct: 222 KLTVESGLSRFPVYEETVDHIIGIFHTRALFKEYVKGGGKMNKVKKKAIDYIMLPYFVPE 281

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +K +  +  + + ++  M I IDE+GG +GLVT+EDI+E I+G+IEDE D+++    R  
Sbjct: 282 TKTISSLFSDMQKKKLQMVITIDEYGGTAGLVTMEDIIEEIMGDIEDESDKKEADVIRFK 341

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
            +    +   ASIED N+        EE  TI G V+    H+P   E   + GY+ ++ 
Sbjct: 342 GK-RIIINGNASIEDVNKTLKLELEHEEYQTIAGYVIDMLDHIPETNERFILKGYRVRIM 400

Query: 268 MADSRRIIQVHVKI 281
             + RRI+++    
Sbjct: 401 KVEDRRIVEMEFTP 414


>UniRef50_UPI00016C05A3 CBS/transporter-associated domain protein n=1 Tax=Epulopiscium sp.
           'N.t. morphotype B' RepID=UPI00016C05A3
          Length = 282

 Score =  270 bits (692), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 70/264 (26%), Positives = 146/264 (55%), Gaps = 5/264 (1%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
           F   L +    +  + + +L LI +  +  +ID  +++M+EG++D   +   ++M PR +
Sbjct: 12  FWGSLFRRQEKKSVSEESILRLIDEGSKEGIIDVTSKEMIEGILDFHGKNANEVMTPRPE 71

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM---RSDAEAFSM 135
           ++ +  ++ +DE +D ++E++ +R PV   D   + G+L  +  L  +   + + +A  +
Sbjct: 72  IVAIDISKDIDEIIDFVLETSFARLPVYEGDVHKVIGVLHVQTFLGHLYKCQRELKAVIL 131

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
           + VL +  +VPE+K + ++LKE ++++ HMAI+ DE+G VSG+VT+ DI+  I+G+I+D 
Sbjct: 132 EDVLDKPYIVPEAKNIKKLLKEMQAEKKHMAIICDEYGDVSGIVTLNDIMLEIIGDIQD- 190

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGE 255
            D+ +D         ++ V  LA ++D N+        E  DT+ G V+   G +P    
Sbjct: 191 -DDSEDTAITLQDDGSYLVDGLAHLDDINKRLNIDLECEHYDTVSGFVIHLLGEIPKDLV 249

Query: 256 TIDIDGYQFKVAMADSRRIIQVHV 279
            ++ +G  F++      R+ ++ +
Sbjct: 250 KVNYNGITFEIKNIKGNRVEKLQI 273


>UniRef50_C1D3R1 Putative hemolysin; putative membrane protein n=1 Tax=Deinococcus
           deserti VCD115 RepID=C1D3R1_DEIDV
          Length = 437

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 84/276 (30%), Positives = 139/276 (50%), Gaps = 7/276 (2%)

Query: 11  TISNKKGFFSLLLSQL----FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           ++ N   FF +   +L     H    + +EL  L R S +  LID   R+M+ GV+++ D
Sbjct: 153 SLFNGTAFFLMRALKLQVDHSHAHVHSPEELEDLYRQSARGGLIDASERNMVAGVLNVED 212

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
           + VR+IM PR++++ +  + T+ E L  +  + ++RFPV  +  D + GI+  + L    
Sbjct: 213 RVVREIMTPRTKLVVVPGHLTVREALARLANTPYTRFPVSGDTPDDVTGIIHLRQLFLAG 272

Query: 127 RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
            S      +  V R  ++V ES  V  + +  R    H AI +DE+GGV+G+ T+ED LE
Sbjct: 273 ESQPGRL-VSDVARPPLIVAESMPVPELWRRLREASRHAAIAVDEYGGVAGMATLEDALE 331

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            I GE++DE+D E+D     +      VR    I+  N+ F      +EVDT+ GL+   
Sbjct: 332 EIFGEMQDEFDHEEDPI--TVDGDRVLVRGDVLIDLLNDRFELDLPTDEVDTVSGLMWHE 389

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
            G LP  G+   +     +V   D R + +    +P
Sbjct: 390 LGRLPMVGDEAGVRNLTLRVEAMDRRAVQRASFILP 425


>UniRef50_Q18E42 CBS domain protein n=11 Tax=Halobacteriaceae RepID=Q18E42_HALWD
          Length = 499

 Score =  270 bits (691), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 80/262 (30%), Positives = 133/262 (50%), Gaps = 4/262 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
             RDE+  LI+   +  +I+ED R+ML+ +       V+++M PR  M  + ++ T++E 
Sbjct: 197 VTRDEIQDLIQTGEREGVIEEDEREMLDRIFQFNQTIVKEVMTPRLDMTAVAKDATIEEA 256

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           ++  + S H R PV   + D++ G +  +DL+           +  +++  + VPESK V
Sbjct: 257 IETCVHSDHERIPVYDGNLDNVIGTVTVRDLVREKHYGEGDIPLTDIVQPTLHVPESKNV 316

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D +L E +  R  M IVIDEFG   GLVT+ED++E IVG+I ++ +EE          + 
Sbjct: 317 DELLTEIQDNRLRMVIVIDEFGTTEGLVTLEDMVEEIVGDILEDDEEEAFEFI---DTNE 373

Query: 212 WTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
             VR   +I++ N+       + EE +T+ G +    G L   GE I  D     +   D
Sbjct: 374 TLVRGEVNIDEVNDELELDLPEGEEFETLAGFIFNRVGRLVEEGEQITFDNITICIEQVD 433

Query: 271 SRRIIQVHVKIPDDSPQPKLDE 292
           + RI++  V  PD S   +  E
Sbjct: 434 NTRIMKARVITPDSSTTKEYSE 455


>UniRef50_C6BSI1 CBS domain containing protein n=2 Tax=Desulfovibrio
           RepID=C6BSI1_DESAD
          Length = 272

 Score =  270 bits (691), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 85/265 (32%), Positives = 148/265 (55%), Gaps = 4/265 (1%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
            ++ +++     +    + +L    ++ ++  I E+   ML  V+++ D    +IMIPR+
Sbjct: 9   LWAKMVNIFKKSDSPLEEHIL----EASEDGEIKEEVVSMLLNVLELKDTEAHEIMIPRT 64

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            MI ++ + +L +  + IIE  HSR PV  E KD I GIL AKD++  +        ++ 
Sbjct: 65  DMIGVEVSSSLSDVAEEIIEHGHSRIPVFKETKDRIVGILHAKDIIAPLLRGKTDTPLED 124

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
           ++R+     E  +V  +L EF++ R H+AI+ DE+GG SGL+T+ED+LE IVG+I DE+D
Sbjct: 125 IMRKPFFASEHIKVKTLLTEFQTGRIHLAILQDEYGGTSGLITMEDVLEEIVGDISDEHD 184

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
            +   DF +L    + +     + + +E        E V++IGG + +  G +P  GE I
Sbjct: 185 ADRPSDFNELENGKFLISGRVPLTEVSERLNLSLDSEHVESIGGYISELTGRIPHVGEFI 244

Query: 258 DIDGYQFKVAMADSRRIIQVHVKIP 282
           +I GY+F V   D+++II + +  P
Sbjct: 245 NISGYKFTVHEGDAKQIISILIDPP 269


>UniRef50_D0LKP6 Putative uncharacterized protein n=1 Tax=Haliangium ochraceum DSM
           14365 RepID=D0LKP6_HALO1
          Length = 420

 Score =  270 bits (691), Expect = 5e-71,   Method: Composition-based stats.
 Identities = 80/272 (29%), Positives = 134/272 (49%), Gaps = 5/272 (1%)

Query: 12  ISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDL--IDEDTRDMLEGVMDIADQRV 69
           +S+     + +L          RDEL  +I    +     I ++ R M+  V++++    
Sbjct: 144 LSSFASTMTRVLGTPAERALITRDELAMIIEAEPREGASEITQEERQMIANVLELSQAGA 203

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF-MRS 128
            D+M+P S++  L  +  L +    + +  HSR PV     D++ G++   DLL     S
Sbjct: 204 VDVMVPLSEVTALPESTPLADAALEVADKQHSRMPVYEGRVDNVIGVVHVFDLLQASTES 263

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
            A   ++ +V R A  VPE+     +L E +    HMAIV+DE+GG  G+VT+ED+LE +
Sbjct: 264 AAGTRTVAEVARPATFVPETMPAGDLLVELQKTGRHMAIVVDEYGGAVGIVTVEDLLEEV 323

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAF 247
           VGEI+DE+D       R      W V A   +E  NE       + E+ +T+ GL++  F
Sbjct: 324 VGEIDDEHDR-PPALIRPERPGVWWVAARTPVERLNEELSLSLPESEDYETVAGLLLDHF 382

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
             +P +GE++ I+    +V  A  R +  V +
Sbjct: 383 KRIPEQGESMVIEQVTIRVLEASERAVEAVQI 414


>UniRef50_C0K042 Hemolysin-related protein n=1 Tax=uncultured bacterium 34R1
           RepID=C0K042_9BACT
          Length = 353

 Score =  269 bits (690), Expect = 6e-71,   Method: Composition-based stats.
 Identities = 87/262 (33%), Positives = 148/262 (56%), Gaps = 9/262 (3%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
             +  + ++L   +  S   DL   D ++ML G++   D+ V +IM PR  ++ L     
Sbjct: 89  KADDISVEDLSRALEAS---DLKSTDEKEMLRGILTFGDKTVSEIMRPRVDVVDLDIELG 145

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
            D+ +  ++E+ +SR PV  E+ D+I+GIL AKDLLP++    + F    ++R A  VPE
Sbjct: 146 FDDVVKAVVENGYSRMPVYEENPDNIKGILYAKDLLPYIGKKDDTFKWQSLMRPAYFVPE 205

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           S+ +D +L++FR ++ HMA+++DEFG   G+ T+ED+LE IVG+I+DEYD E+   F ++
Sbjct: 206 SRMIDDLLEDFRKKKIHMAVIVDEFGCTQGIATLEDVLEEIVGDIDDEYDTEEKY-FTRV 264

Query: 208 SRHTWTVRALASIEDFNEAFGTH---FSD--EEVDTIGGLVMQAFGHLPARGETIDIDGY 262
           + +T+   A   ++DF EA       F+D  +E +T+ GL++   G      E +     
Sbjct: 265 AENTYIFDAKTPLDDFFEATCIDENNFADHLDEAETLAGLLLSLKGDFLKEKEELKTAPC 324

Query: 263 QFKVAMADSRRIIQVHVKIPDD 284
            F V      RI +V V++  +
Sbjct: 325 TFTVLKVKKYRIAKVKVEVKPE 346


>UniRef50_C3RN25 Putative uncharacterized protein n=1 Tax=Mollicutes bacterium D7
           RepID=C3RN25_9MOLU
          Length = 428

 Score =  269 bits (690), Expect = 6e-71,   Method: Composition-based stats.
 Identities = 81/264 (30%), Positives = 138/264 (52%), Gaps = 1/264 (0%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           F  +L      G     ++L  ++    +  +++E  ++M+  V +  +  +++IM PR 
Sbjct: 154 FIKILGGARDSGPTMTEEDLKTIVTVGHEEGVLEEQEKEMIHNVFEFGETEIKEIMTPRI 213

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            + ++  + +  E +++   S  SR+PV SE  D I G+L  KDLL F   D + F +  
Sbjct: 214 HVESIPDDCSYQELMEIYQRSQFSRYPVHSESFDEIVGVLNVKDLL-FFNIDPDEFVVKD 272

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
            +R   VV E   V  +    R +   +AIV+DE+G +SG+VT EDI+E IVGEI+DEYD
Sbjct: 273 FMRDTFVVYEFNEVADVFASMRKEHATLAIVLDEYGVMSGIVTFEDIVEEIVGEIDDEYD 332

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
            E+D     L  + + +    ++ + N+  GT F  E+ ++IGGLV+     +P   + +
Sbjct: 333 AEEDEMIIFLGENEYLIDGSLNLNEVNDRVGTDFDSEDFESIGGLVLGEVSGVPEIDDEV 392

Query: 258 DIDGYQFKVAMADSRRIIQVHVKI 281
            I+   FK+      RI Q+ V I
Sbjct: 393 QIENVIFKIVKMHKNRIAQLKVTI 416


>UniRef50_Q6ZUX1 cDNA FLJ43252 fis, clone HEART2006909 n=23 Tax=cellular organisms
           RepID=Q6ZUX1_HUMAN
          Length = 307

 Score =  269 bits (690), Expect = 6e-71,   Method: Composition-based stats.
 Identities = 88/254 (34%), Positives = 148/254 (58%), Gaps = 9/254 (3%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + D+L   +  + ++D+  +D + ML+G++   D+  +++M  R  ++ L  + T  E L
Sbjct: 54  SVDDLEQALELTDKDDI--KDEQSMLKGIIRFGDETAKEVMTSRQNIVDLDIHSTYPEVL 111

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
             I E+ +SR PV  ++ D+I GIL  KDLLP +     +F    ++R    VPE+K++D
Sbjct: 112 KCIAENNYSRIPVYQDNTDNIRGILYIKDLLPHL-EKPVSFRWQSLIRPPYFVPETKKID 170

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+EF+  + H+AIV+DEFGG SG+VT+EDILE IVGEI DEYDEE+   + +L+ +T+
Sbjct: 171 DLLREFQENKVHIAIVVDEFGGTSGIVTLEDILEEIVGEINDEYDEEEKF-YSKLNYNTF 229

Query: 213 TVRALASIEDFNEAFG-----THFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
                  + DF +            + + DT+ GL+++  G  P+  E I+   Y F+V 
Sbjct: 230 IFEGKTLLTDFCKILNVDDEEFEEVEGDADTLAGLLLEIKGDFPSIHEKIEYKNYSFEVL 289

Query: 268 MADSRRIIQVHVKI 281
             + RRI ++ V +
Sbjct: 290 GVEERRISRIKVVV 303


>UniRef50_B8FGS6 Putative uncharacterized protein n=1 Tax=Desulfatibacillum
           alkenivorans AK-01 RepID=B8FGS6_DESAA
          Length = 412

 Score =  269 bits (690), Expect = 7e-71,   Method: Composition-based stats.
 Identities = 79/267 (29%), Positives = 144/267 (53%), Gaps = 5/267 (1%)

Query: 18  FFSLLLSQLFHG---EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
             S+LL++            DE+ +++    +   ++ED R M+  +   +D    +IM 
Sbjct: 145 LLSVLLAKPLKSSAQPIITEDEIKSVVTLGEEIGEVEEDERIMIHNIFRFSDLEAYEIMT 204

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
            R+ + +     T+++    ++   +SR P+    +D+I GIL AKD+L  + S  E  +
Sbjct: 205 DRTAIFSAPAEFTVEKVAKEVVLRGYSRIPIYENKRDNIVGILYAKDMLNALISGKEKAA 264

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           + ++ R  + VPE+  +D +LK+F+ +R HMA+V+DE GGV GL+TIED+LE IVG+I D
Sbjct: 265 LKELARPVMFVPETILLDDLLKQFQKERVHMAMVVDEHGGVGGLITIEDLLEEIVGDIVD 324

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPAR 253
           E D+E  +   +  +    V+    +E+ N       S+ E+ +TI G ++     +P  
Sbjct: 325 ETDKE-QVMIHKTGKKKALVKGQTEVEEVNRVLHLGISEHEDFETISGFILSKMRKIPEP 383

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVK 280
           GE ++I     ++  AD+R I +V ++
Sbjct: 384 GEELNIGDIVIRITKADNRHIEEVEIE 410


>UniRef50_D0M5E7 Hemolysin n=15 Tax=Vibrionales RepID=D0M5E7_VIBSE
          Length = 434

 Score =  269 bits (690), Expect = 7e-71,   Method: Composition-based stats.
 Identities = 70/282 (24%), Positives = 128/282 (45%), Gaps = 8/282 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +   F  LL     +GE    +++ A++ +  ++  I+   + M+  ++ + D+    +M
Sbjct: 155 STDTFLRLLRQNDSNGEIVTEEDIFAIVSEGSESGAIEPQEQLMIRNLLHLNDRLALSLM 214

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR  +  L  NQ +D  L  + ++ HS +PV     D+I G + +K LL     +    
Sbjct: 215 TPRCDIHYLDANQPIDVILTDLRQTQHSVWPVCKGSLDNIIGTISSKVLLDEY-DELSIS 273

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + K L++   VPES +   +L   +     M  ++DE+G V GLVT+ D+L+ I GE+ 
Sbjct: 274 KLAKQLKRPRFVPESMKGLPLLNYMQQTSAEMVFIVDEYGDVQGLVTLYDLLKSIAGEL- 332

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH----FSDEEVDTIGGLVMQAFGH 249
                   +  +Q    +W + AL  + +               E   T+ GL+   +G 
Sbjct: 333 --GMAPQQVWAKQQKDGSWLMDALIPLNELKNKLELSSIEGEEREGFQTLNGLLTWLYGR 390

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           +P  GE I   G++F + +    RI+QV V    D+P    +
Sbjct: 391 VPNVGEHIHYQGWRFDILLVKKHRIMQVRVTKDTDTPTNNSE 432


>UniRef50_C7MLQ1 CBS domain-containing protein n=8 Tax=Coriobacteriaceae
           RepID=C7MLQ1_CRYCD
          Length = 443

 Score =  269 bits (689), Expect = 7e-71,   Method: Composition-based stats.
 Identities = 85/254 (33%), Positives = 142/254 (55%), Gaps = 12/254 (4%)

Query: 23  LSQLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           L++LFH +        + DE+  +++D+ +   +  D + M+  ++D+AD   RDIM PR
Sbjct: 164 LARLFHVKSVDERQAVSEDEIKYIVKDNEE---LLPDEKRMIHEILDLADATARDIMTPR 220

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
           + +I ++  +T+ E L+ +  + +SR PV  ED D I G++  KDL+P +  D E  ++D
Sbjct: 221 ADIIFVEDTETVKETLNRMRGTGYSRLPVYHEDYDRIVGVVKYKDLIPAIMDDREDATVD 280

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
           +   +   VPE+K +  +L E ++ R  +AIV+DE+GG  GL+TIEDI+E IVGEI DE 
Sbjct: 281 EFTDEVYFVPETKDIFPLLSEMQTNRQQIAIVVDEYGGTDGLITIEDIVEEIVGEIIDET 340

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGE 255
           D E      QL+   W V     ++D  E       + ++ +TI G ++     +P  G+
Sbjct: 341 DLESRY-VTQLTDGEWLVDGSLPVDDAIE-LSWPLEESDDYETIAGWLIDMVDTIPQIGD 398

Query: 256 TIDIDGYQFKVAMA 269
           + D  GY+F V   
Sbjct: 399 SYDFGGYRFTVQSM 412


>UniRef50_C3J7T2 CBS domain pair n=4 Tax=Bacteria RepID=C3J7T2_9PORP
          Length = 435

 Score =  269 bits (689), Expect = 8e-71,   Method: Composition-based stats.
 Identities = 82/240 (34%), Positives = 138/240 (57%), Gaps = 7/240 (2%)

Query: 51  DEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDK 110
           +E    ++  ++   D+   +IM+PR  M+ +         L  ++++ +SR PV    +
Sbjct: 195 NETQSKLIGEIIKFHDKTADEIMVPRVDMVMIDYQWDFATTLRFVLDAGYSRIPVFLGTQ 254

Query: 111 DHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVID 170
           D I+GIL  KD LP+  + ++ F    ++R A  VPE+K++D +L+EFRS+  H++IV+D
Sbjct: 255 DVIKGILYIKDCLPYTTAGSD-FDWHTLIRPANFVPENKKIDDLLEEFRSEHRHISIVVD 313

Query: 171 EFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH 230
           E+GG SGL+T+EDILE IVGEI DEYD ED++ + +L+  ++       I DF       
Sbjct: 314 EYGGTSGLITLEDILEEIVGEITDEYD-EDELPYTRLADGSFLFEGKTQINDFCRYLSLE 372

Query: 231 FS-----DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            S      +E+DT+GG+ ++    LP  G  +   GY+F++   +  RI+Q+ V  P  +
Sbjct: 373 DSLFEPLTQEIDTLGGVFLELKQELPRVGAFVTYRGYRFEITKVEKHRIMQMRVIPPATA 432


>UniRef50_UPI0001C3727C hypothetical protein RflaF_01904 n=1 Tax=Ruminococcus flavefaciens
           FD-1 RepID=UPI0001C3727C
          Length = 440

 Score =  269 bits (689), Expect = 9e-71,   Method: Composition-based stats.
 Identities = 72/275 (26%), Positives = 127/275 (46%), Gaps = 5/275 (1%)

Query: 11  TISNKKGFFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           T ++  G   L       G E    +E+L +     +   ID+D   +++ V    D   
Sbjct: 157 TNASANGILRLFGIDPDSGAETVTEEEILMMSDAGAEKGTIDQDENRIIKNVFAFDDLTA 216

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
             +   R+ +  L      +   + I  + HS FPV  E  D++ G+L AKD        
Sbjct: 217 EQVCTHRTDVSVLWSKDDTEVWEETIHRTRHSVFPVCGESVDNVIGVLDAKDYFRLDDKS 276

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRY-HMAIVIDEFGGVSGLVTIEDILELI 188
            +   M+  +R+ + V E+ + DR+ ++ +     H A+V+DE+GG+SG+VTI D++E +
Sbjct: 277 RDNI-MENAVREPLFVHENMKADRLFEQMKQDGSDHFAVVVDEYGGMSGIVTITDLVEQL 335

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VG+  D+ ++E  +   Q     WTV  ++++ +  +        ++ DT GG V+   G
Sbjct: 336 VGDFADDPEDEPAVKLTQTGDDEWTVPGISALTEVCDELDITLPADKYDTFGGYVIDRLG 395

Query: 249 HLPARGETI--DIDGYQFKVAMADSRRIIQVHVKI 281
           H+P  G  +  D DG    V      RI    VK+
Sbjct: 396 HIPKNGTQVSLDTDGLHIDVTEVKHHRIEVCKVKV 430


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q5SKB4 Hemolysin-related protein n=3 Tax=Thermus RepID=...   349   8e-95
UniRef50_B8G6A7 Putative uncharacterized protein n=3 Tax=Chlorof...   343   6e-93
UniRef50_B8I559 Putative uncharacterized protein n=1 Tax=Clostri...   337   2e-91
UniRef50_Q1AX40 Putative uncharacterized protein n=1 Tax=Rubroba...   336   5e-91
UniRef50_D1CDD2 CBS domain containing protein n=1 Tax=Thermobacu...   336   7e-91
UniRef50_A9WFQ5 CBS domain containing protein n=4 Tax=Chloroflex...   334   2e-90
UniRef50_D2DIN9 CBS domain-containing protein n=1 Tax=uncultured...   334   3e-90
UniRef50_D1N3F2 Putative uncharacterized protein n=1 Tax=Victiva...   334   3e-90
UniRef50_C1SMP1 CBS domain-containing protein n=1 Tax=Denitrovib...   332   7e-90
UniRef50_C7IJK2 CBS domain containing protein n=5 Tax=Firmicutes...   331   2e-89
UniRef50_B7IDY0 Integral membrane protein with CBS domains n=4 T...   331   2e-89
UniRef50_B8CXI7 Putative membrane CBS domain protein n=1 Tax=Hal...   330   3e-89
UniRef50_D0MD79 CBS domain containing protein n=1 Tax=Rhodotherm...   330   4e-89
UniRef50_A5UY55 Putative uncharacterized protein n=3 Tax=Chlorof...   327   2e-88
UniRef50_B2I8U5 CBS domain containing protein n=17 Tax=Xanthomon...   327   2e-88
UniRef50_B0PAE4 Putative uncharacterized protein n=2 Tax=Clostri...   326   4e-88
UniRef50_A7HLR9 Putative uncharacterized protein n=1 Tax=Fervido...   326   5e-88
UniRef50_Q3A2F6 Uncharacterized CBS domain-containing protein n=...   325   9e-88
UniRef50_Q47RN3 CBS domain protein n=1 Tax=Thermobifida fusca YX...   324   2e-87
UniRef50_A7NHB2 CBS domain containing protein n=1 Tax=Roseiflexu...   324   3e-87
UniRef50_D1B5K7 Putative uncharacterized protein n=1 Tax=Therman...   324   3e-87
UniRef50_Q1IYV3 CBS domain-containing protein DUF21 n=4 Tax=Bact...   323   4e-87
UniRef50_C7GAD7 CBS domain protein n=9 Tax=Bacteria RepID=C7GAD7...   322   9e-87
UniRef50_C5VQE4 CBS domain integral membrane protein n=9 Tax=Clo...   321   2e-86
UniRef50_B8G2E5 Putative uncharacterized protein n=3 Tax=Clostri...   321   2e-86
UniRef50_Q74EV6 CBS domain protein n=9 Tax=Desulfuromonadales Re...   321   3e-86
UniRef50_C1TQS8 CBS domain-containing protein n=2 Tax=Synergista...   321   3e-86
UniRef50_D2LWG5 Putative uncharacterized protein n=3 Tax=Bacillu...   320   5e-86
UniRef50_A4VQY6 Metal ion transporter, putative n=2 Tax=Gammapro...   319   5e-86
UniRef50_C6L9Q9 CBS domain protein n=6 Tax=Clostridiales RepID=C...   319   7e-86
UniRef50_Q3JVV5 Magnesium and cobalt efflux protein CorC n=105 T...   318   1e-85
UniRef50_D1Y8K6 CBS/transporter domain protein n=1 Tax=Pyramidob...   318   1e-85
UniRef50_B9KAC3 Hemolysin-related protein n=1 Tax=Thermotoga nea...   316   5e-85
UniRef50_Q48DN5 Metal ion transporter, putative n=16 Tax=Proteob...   316   7e-85
UniRef50_Q2JP27 Putative transporter, HlyC/CorC (HCC) family n=2...   316   8e-85
UniRef50_A9BGT5 Putative uncharacterized protein n=1 Tax=Petroto...   315   1e-84
UniRef50_A9KQ60 Putative uncharacterized protein n=8 Tax=Clostri...   315   1e-84
UniRef50_Q3SVM7 Mg2+ and Co2+ transporter CorB family n=15 Tax=A...   315   1e-84
UniRef50_A1WVF4 CBS domain containing protein n=2 Tax=Ectothiorh...   314   2e-84
UniRef50_B5YFP5 CBS domain protein n=1 Tax=Thermodesulfovibrio y...   314   3e-84
UniRef50_C7LZP2 CBS domain containing protein n=1 Tax=Acidimicro...   313   4e-84
UniRef50_C1ZDU6 CBS domain-containing protein n=1 Tax=Planctomyc...   313   4e-84
UniRef50_Q72A49 CBS/transporter associated domain protein n=4 Ta...   313   5e-84
UniRef50_UPI0001C36BB6 hypothetical protein ChatD1_07246 n=1 Tax...   312   6e-84
UniRef50_D0KZZ4 CBS domain containing protein n=1 Tax=Halothioba...   312   8e-84
UniRef50_A1AQM4 CBS domain containing protein n=9 Tax=Desulfurom...   312   9e-84
UniRef50_C5PXG9 TlyC family hemolysin n=5 Tax=Sphingobacteriales...   312   1e-83
UniRef50_C3WJU6 Magnesium and cobalt efflux protein corC n=15 Ta...   312   1e-83
UniRef50_B7GEW2 Hemolysin related protein containing CBS domains...   312   1e-83
UniRef50_D2RIW5 CBS domain containing protein n=2 Tax=Acidaminoc...   311   2e-83
UniRef50_B7RC07 CBS domain integral membrane protein n=5 Tax=The...   311   2e-83
UniRef50_A9B0K1 Putative uncharacterized protein n=1 Tax=Herpeto...   311   3e-83
UniRef50_D1AFV9 Putative uncharacterized protein n=1 Tax=Sebalde...   311   3e-83
UniRef50_D1C4W4 Putative uncharacterized protein n=1 Tax=Sphaero...   311   3e-83
UniRef50_B9Z7Q6 Putative uncharacterized protein n=1 Tax=Lutiell...   310   4e-83
UniRef50_P74409 UPF0053 protein sll0260 n=28 Tax=cellular organi...   309   5e-83
UniRef50_A9KLG3 Putative uncharacterized protein n=1 Tax=Clostri...   309   6e-83
UniRef50_B7J5B5 Magnesium and cobalt efflux protein, putative n=...   309   7e-83
UniRef50_C4Z1L1 Putative hemolysin n=2 Tax=Bacteria RepID=C4Z1L1...   309   8e-83
UniRef50_C9L5N7 Hemolysin-related protein n=1 Tax=Blautia hansen...   309   8e-83
UniRef50_B8JAD7 Putative uncharacterized protein n=4 Tax=Anaerom...   309   9e-83
UniRef50_C6J8N4 Putative uncharacterized protein n=1 Tax=Ruminoc...   309   1e-82
UniRef50_Q2FTJ8 Putative uncharacterized protein n=4 Tax=Methano...   308   1e-82
UniRef50_B3QS78 Putative uncharacterized protein n=3 Tax=Bacteri...   308   1e-82
UniRef50_A3ZXV1 Hemolysin protein n=1 Tax=Blastopirellula marina...   308   1e-82
UniRef50_B2V0W8 Putative membrane CBS domain protein n=14 Tax=Cl...   307   2e-82
UniRef50_A0PYY8 Integral membrane protein with CBS domains n=15 ...   307   3e-82
UniRef50_B8J2R3 CBS domain containing protein n=3 Tax=Desulfovib...   307   3e-82
UniRef50_Q1DCR5 CBS/transporter associated domain protein n=2 Ta...   307   4e-82
UniRef50_B6IU27 CBS domain protein n=2 Tax=Rhodospirillum RepID=...   307   4e-82
UniRef50_P67130 UPF0053 protein Rv2366c/MT2435 n=36 Tax=Actinomy...   307   4e-82
UniRef50_B5JWG7 CBS domain containing protein n=3 Tax=Gammaprote...   306   4e-82
UniRef50_D1C1Y5 CBS domain containing protein n=1 Tax=Sphaerobac...   306   7e-82
UniRef50_Q5ZVK1 Mg2+ and Co2+ transporter CorC n=6 Tax=Legionell...   306   7e-82
UniRef50_B5YET1 GldE n=2 Tax=Dictyoglomus RepID=B5YET1_DICT6          306   7e-82
UniRef50_Q9KTE3 Magnesium and cobalt efflux protein corC n=42 Ta...   305   1e-81
UniRef50_D1Y8K5 Putative transporter n=1 Tax=Pyramidobacter pisc...   305   1e-81
UniRef50_C6IW85 Putative uncharacterized protein n=1 Tax=Paeniba...   305   1e-81
UniRef50_B0MHL2 Putative uncharacterized protein n=2 Tax=Bacteri...   304   2e-81
UniRef50_A3EP54 Putative uncharacterized protein n=2 Tax=Leptosp...   304   2e-81
UniRef50_A6CBK3 Hemolysin protein n=1 Tax=Planctomyces maris DSM...   304   2e-81
UniRef50_C5EUB4 Membrane-anchored CBS domain-containing protein-...   304   2e-81
UniRef50_B2V0V1 CBS/transporter domain protein n=18 Tax=Clostrid...   304   2e-81
UniRef50_C3L2Y2 Transporter, HlyC/CorC family n=26 Tax=Bacteria ...   304   3e-81
UniRef50_B9L251 Magnesium and cobalt efflux protein corC n=1 Tax...   304   3e-81
UniRef50_UPI0001BCCCA8 CBS domain-containing protein n=1 Tax=Aer...   304   3e-81
UniRef50_C7DFD3 CBS domain protein n=6 Tax=Rhodobacteraceae RepI...   304   3e-81
UniRef50_C8WNW4 Putative uncharacterized protein n=1 Tax=Eggerth...   303   4e-81
UniRef50_A8KYW4 CBS domain containing protein n=33 Tax=Actinomyc...   303   5e-81
UniRef50_D2LDC4 Putative uncharacterized protein n=1 Tax=Rhodomi...   302   8e-81
UniRef50_Q7VRA4 Haemolysin-related protein n=2 Tax=Candidatus Bl...   302   9e-81
UniRef50_B9ZL46 CBS domain containing protein n=2 Tax=Gammaprote...   302   9e-81
UniRef50_C6W3X5 Putative uncharacterized protein n=1 Tax=Dyadoba...   302   1e-80
UniRef50_B5Y9X2 CBS domain protein n=1 Tax=Coprothermobacter pro...   301   2e-80
UniRef50_Q1K126 CBS domain protein n=2 Tax=Desulfuromonadales Re...   301   3e-80
UniRef50_A4FLP3 Magnesium and cobalt efflux protein CorC n=3 Tax...   301   3e-80
UniRef50_C8VVX2 Putative uncharacterized protein n=2 Tax=Clostri...   301   3e-80
UniRef50_Q1YQV9 Magnesium and cobalt efflux protein CorC n=1 Tax...   301   3e-80
UniRef50_Q2NIR0 Hymolysin-related protein n=5 Tax=Candidatus Phy...   300   3e-80
UniRef50_A8DJD8 CBS domain protein n=1 Tax=Candidatus Chloracido...   300   4e-80
UniRef50_C8XF87 CBS domain containing protein n=11 Tax=Bacteria ...   300   4e-80
UniRef50_D1AH17 Putative uncharacterized protein n=1 Tax=Sebalde...   300   5e-80
UniRef50_C2MBP5 Gliding motility-associated protein GldE n=1 Tax...   300   5e-80
UniRef50_A2SJR8 CBS domain protein n=8 Tax=Burkholderiales RepID...   299   5e-80
UniRef50_C9KJP9 CBS domain protein n=3 Tax=Veillonellaceae RepID...   299   8e-80
UniRef50_Q609I4 CBS domain protein n=2 Tax=Proteobacteria RepID=...   299   9e-80
UniRef50_C7NDD7 CBS domain containing protein n=3 Tax=Leptotrich...   299   1e-79
UniRef50_B6JNY8 Hemolysin domain-containing protein n=23 Tax=Cam...   298   1e-79
UniRef50_A9F240 Conserved hypothetical membrane protein n=1 Tax=...   298   2e-79
UniRef50_A4EBJ7 Putative uncharacterized protein n=1 Tax=Collins...   297   2e-79
UniRef50_C8X404 CBS domain containing protein n=2 Tax=Desulfovib...   297   2e-79
UniRef50_C0CHP0 Putative uncharacterized protein n=1 Tax=Blautia...   297   2e-79
UniRef50_C7RRT5 CBS domain containing protein n=1 Tax=Candidatus...   297   3e-79
UniRef50_C3MCE9 Putative uncharacterized protein n=1 Tax=Rhizobi...   297   3e-79
UniRef50_B8GI66 Putative uncharacterized protein n=1 Tax=Methano...   297   3e-79
UniRef50_A5EY48 Transporter associated domain protein n=2 Tax=Ca...   297   3e-79
UniRef50_C1ZED0 CBS domain-containing protein n=1 Tax=Planctomyc...   297   3e-79
UniRef50_C4V614 TlyC family hemolysin n=14 Tax=cellular organism...   297   3e-79
UniRef50_C6QET7 Putative uncharacterized protein n=1 Tax=Hyphomi...   297   3e-79
UniRef50_D1VUR6 CBS/transporter domain protein n=1 Tax=Peptoniph...   297   3e-79
UniRef50_Q310P2 CBS n=6 Tax=Desulfovibrionaceae RepID=Q310P2_DESDG    297   4e-79
UniRef50_B9Y7L5 Putative uncharacterized protein n=1 Tax=Holdema...   297   4e-79
UniRef50_Q2FN37 Putative uncharacterized protein n=1 Tax=Methano...   297   4e-79
UniRef50_Q30WW6 CBS n=5 Tax=Proteobacteria RepID=Q30WW6_DESDG         297   4e-79
UniRef50_Q1IKR7 Putative uncharacterized protein n=1 Tax=Candida...   296   5e-79
UniRef50_Q67QV0 Putative hemolysin n=1 Tax=Symbiobacterium therm...   296   5e-79
UniRef50_C8P0P9 CBS domain protein n=1 Tax=Erysipelothrix rhusio...   296   5e-79
UniRef50_C0EHV3 Putative uncharacterized protein n=1 Tax=Clostri...   296   7e-79
UniRef50_Q9CM13 Magnesium and cobalt efflux protein corC n=264 T...   296   7e-79
UniRef50_A2SSZ1 Putative uncharacterized protein n=1 Tax=Methano...   296   9e-79
UniRef50_Q164J1 CBS domain protein n=37 Tax=Rhodobacterales RepI...   296   9e-79
UniRef50_A8SE58 Putative uncharacterized protein n=2 Tax=Bacteri...   296   9e-79
UniRef50_Q7NMI1 Glr0785 protein n=2 Tax=Bacteria RepID=Q7NMI1_GLOVI   296   1e-78
UniRef50_A0LG68 CBS domain containing protein n=1 Tax=Syntrophob...   295   1e-78
UniRef50_A0LRV3 Putative uncharacterized protein n=1 Tax=Acidoth...   295   1e-78
UniRef50_C7HS55 Transporter n=3 Tax=Anaerococcus RepID=C7HS55_9FIRM   295   1e-78
UniRef50_C0FYH2 Putative uncharacterized protein n=1 Tax=Rosebur...   295   1e-78
UniRef50_C9LMB7 Putative transporter n=1 Tax=Dialister invisus D...   295   1e-78
UniRef50_B8J8L5 CBS domain containing protein n=4 Tax=Anaeromyxo...   295   1e-78
UniRef50_C9KMQ2 CBS domain protein n=1 Tax=Mitsuokella multacida...   294   2e-78
UniRef50_A5ZVW9 Putative uncharacterized protein n=1 Tax=Ruminoc...   294   2e-78
UniRef50_D1Y9A3 CBS domain protein n=3 Tax=Propionibacterium acn...   294   2e-78
UniRef50_B8KMV1 Magnesium and cobalt efflux protein CorC n=3 Tax...   294   2e-78
UniRef50_Q6MCC0 Putative uncharacterized protein n=2 Tax=Parachl...   294   3e-78
UniRef50_C2ECT1 Hemolysin n=1 Tax=Lactobacillus ruminis ATCC 256...   294   3e-78
UniRef50_UPI0001BC3544 hypothetical protein BcroD2_01764 n=1 Tax...   294   3e-78
UniRef50_C2HJY2 HCC HlyC/CorC family transporter n=2 Tax=Finegol...   294   3e-78
UniRef50_Q0C626 CBS/transporter domain protein n=7 Tax=Alphaprot...   293   4e-78
UniRef50_D1VTC9 Integral membrane protein n=1 Tax=Peptoniphilus ...   293   4e-78
UniRef50_D1CH59 Putative uncharacterized protein n=1 Tax=Thermob...   293   5e-78
UniRef50_A9VF50 Putative uncharacterized protein n=6 Tax=Bacillu...   293   5e-78
UniRef50_A8ZTS5 Putative uncharacterized protein n=2 Tax=Desulfo...   293   5e-78
UniRef50_C2BH63 HCC HlyC/CorC family transporter n=2 Tax=Anaeroc...   293   6e-78
UniRef50_Q3ZYX1 Probable hemolysin-related protein n=5 Tax=Dehal...   292   6e-78
UniRef50_Q6N606 Probable HlyC/CorC family of transporters with 2...   292   1e-77
UniRef50_D1BMR3 Transporter-associated region n=3 Tax=Veillonell...   292   1e-77
UniRef50_C4L4N6 Putative uncharacterized protein n=2 Tax=Bacilla...   292   1e-77
UniRef50_C4GBW1 Putative uncharacterized protein n=1 Tax=Shuttle...   292   1e-77
UniRef50_C3X3R1 Magnesium and cobalt efflux protein n=1 Tax=Oxal...   291   1e-77
UniRef50_A8PND0 Magnesium and cobalt efflux protein CorC n=1 Tax...   291   1e-77
UniRef50_UPI0001C360F2 putative hemolysin-related protein n=2 Ta...   291   2e-77
UniRef50_C1A9X1 Hypothetical membrane protein n=1 Tax=Gemmatimon...   291   2e-77
UniRef50_B1I646 Putative uncharacterized protein n=1 Tax=Candida...   291   2e-77
UniRef50_A6U9C9 Putative uncharacterized protein n=2 Tax=Sinorhi...   291   2e-77
UniRef50_A1QYK9 Magnesium and cobalt efflux protein CorC n=21 Ta...   291   2e-77
UniRef50_Q87DZ3 Hemolysin n=20 Tax=Xanthomonadaceae RepID=Q87DZ3...   290   3e-77
UniRef50_C6LCF2 CBS domain protein n=1 Tax=Bryantella formatexig...   290   3e-77
UniRef50_B6FN86 Putative uncharacterized protein n=2 Tax=Clostri...   289   5e-77
UniRef50_Q6MC55 Putative uncharacterized protein n=1 Tax=Candida...   289   6e-77
UniRef50_C0W312 HCC HlyC/CorC family transporter n=1 Tax=Actinom...   289   6e-77
UniRef50_A9I003 Magnesium and cobalt efflux protein n=5 Tax=Bord...   289   6e-77
UniRef50_UPI000050F785 CBS domain-containing protein n=1 Tax=Bre...   289   7e-77
UniRef50_UPI000196CD6F hypothetical protein CATMIT_02806 n=1 Tax...   289   7e-77
UniRef50_A6CIW3 Probable hemolysin n=2 Tax=Bacillus RepID=A6CIW3...   289   7e-77
UniRef50_A0JX40 CBS domain containing protein n=4 Tax=Micrococca...   289   9e-77
UniRef50_A7VVN2 Putative uncharacterized protein n=1 Tax=Clostri...   289   9e-77
UniRef50_C4ZBH2 Hemolysin n=1 Tax=Eubacterium rectale ATCC 33656...   289   1e-76
UniRef50_Q01WS1 Putative uncharacterized protein n=1 Tax=Candida...   289   1e-76
UniRef50_UPI0001973384 hypothetical protein ClM62_01605 n=1 Tax=...   289   1e-76
UniRef50_C7LQH5 Putative uncharacterized protein n=1 Tax=Desulfo...   289   1e-76
UniRef50_Q1IKR3 CBS domain protein n=1 Tax=Candidatus Koribacter...   289   1e-76
UniRef50_C7RN87 Putative uncharacterized protein n=1 Tax=Candida...   288   1e-76
UniRef50_Q8YM44 All5096 protein n=16 Tax=Cyanobacteria RepID=Q8Y...   288   2e-76
UniRef50_C9RLZ8 CBS domain containing protein n=1 Tax=Fibrobacte...   287   3e-76
UniRef50_A4J4V5 Putative uncharacterized protein n=1 Tax=Desulfo...   287   3e-76
UniRef50_A9NGP1 Putative hemolysin-related protein n=2 Tax=Bacte...   287   3e-76
UniRef50_B3WFB2 Transport protein n=8 Tax=Lactobacillus RepID=B3...   287   4e-76
UniRef50_D0MK91 CBS domain containing protein n=1 Tax=Rhodotherm...   287   4e-76
UniRef50_C4GJN3 Putative uncharacterized protein n=1 Tax=Kingell...   286   4e-76
UniRef50_C6NUU3 Magnesium and cobalt efflux protein CorC n=1 Tax...   286   6e-76
UniRef50_Q9LG18 F14J16.20 n=17 Tax=Magnoliophyta RepID=Q9LG18_ARATH   286   6e-76
UniRef50_C6HVJ5 Putative uncharacterized protein n=1 Tax=Leptosp...   286   6e-76
UniRef50_D2NSB8 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NS...   286   7e-76
UniRef50_A6LDG3 Hemolysin-related protein n=23 Tax=Bacteroidales...   286   7e-76
UniRef50_A9U7Q9 Predicted protein (Fragment) n=1 Tax=Physcomitre...   286   7e-76
UniRef50_UPI0001C3727C hypothetical protein RflaF_01904 n=1 Tax=...   286   7e-76
UniRef50_Q1K2A8 Putative uncharacterized protein n=1 Tax=Desulfu...   285   8e-76
UniRef50_Q0G3C6 Putative uncharacterized protein n=2 Tax=Auranti...   285   9e-76
UniRef50_A7HZ85 CBS domain containing protein n=1 Tax=Parvibacul...   285   1e-75
UniRef50_A7VCA4 Putative uncharacterized protein n=2 Tax=Clostri...   285   1e-75
UniRef50_B8GZ20 Magnesium and cobalt efflux protein corC-like pr...   285   1e-75
UniRef50_C0QRS4 CBS/transporter-associated domain protein n=5 Ta...   285   1e-75
UniRef50_A6T3M6 Hemolysin n=3 Tax=Oxalobacteraceae RepID=A6T3M6_...   285   1e-75
UniRef50_C9MVS3 CBS domain protein n=3 Tax=Fusobacteriaceae RepI...   285   1e-75
UniRef50_A7VIV6 Putative uncharacterized protein n=2 Tax=Clostri...   285   1e-75
UniRef50_C0QYZ5 Hemolysin protein n=2 Tax=Brachyspira RepID=C0QY...   285   1e-75
UniRef50_C1DQL5 Hemolysin-like protein n=2 Tax=Proteobacteria Re...   285   1e-75
UniRef50_D0LKP6 Putative uncharacterized protein n=1 Tax=Haliang...   285   2e-75
UniRef50_D2BD19 Putative uncharacterized protein n=1 Tax=Strepto...   285   2e-75
UniRef50_C1DDZ1 Mg/Co transporter-like protein n=7 Tax=Pseudomon...   285   2e-75
UniRef50_D2NT77 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NT...   285   2e-75
UniRef50_B1YJR8 Putative uncharacterized protein n=1 Tax=Exiguob...   285   2e-75
UniRef50_Q01P08 CBS domain containing protein n=1 Tax=Candidatus...   284   2e-75
UniRef50_C4G6D4 Putative uncharacterized protein n=1 Tax=Abiotro...   284   2e-75
UniRef50_C8NR98 Transport protein n=2 Tax=Corynebacterium effici...   284   3e-75
UniRef50_A5CRB2 Conserved membrane protein n=4 Tax=Actinobacteri...   283   4e-75
UniRef50_C9LYN4 CBS domain protein n=2 Tax=Selenomonas RepID=C9L...   283   4e-75
UniRef50_C0W0A3 HCC HlyC/CorC family transporter n=1 Tax=Actinom...   283   4e-75
UniRef50_A9BXY0 CBS domain containing protein n=17 Tax=cellular ...   283   4e-75
UniRef50_B6FYX0 Putative uncharacterized protein n=1 Tax=Clostri...   283   4e-75
UniRef50_Q8PS13 Conserved protein n=2 Tax=Methanosarcina RepID=Q...   283   5e-75
UniRef50_UPI0001B44AE5 CBS domain protein n=1 Tax=Listeria monoc...   283   5e-75
UniRef50_Q2W097 Putative Mg2+ and Co2+ transporter CorB n=1 Tax=...   283   5e-75
UniRef50_C0GM71 CBS domain containing protein n=1 Tax=Desulfonat...   283   5e-75
UniRef50_C7MLQ1 CBS domain-containing protein n=8 Tax=Coriobacte...   283   5e-75
UniRef50_C6J7K3 Putative uncharacterized protein n=2 Tax=Bacilla...   283   6e-75
UniRef50_C1F1N4 CBS/transporter domain protein n=1 Tax=Acidobact...   282   8e-75
UniRef50_C4GB29 Putative uncharacterized protein n=1 Tax=Shuttle...   282   9e-75
UniRef50_A9NG07 Membrane-anchored CBS-domain containing protein ...   282   9e-75
UniRef50_C1F7E2 CBS/transporter domain protein n=1 Tax=Acidobact...   282   1e-74
UniRef50_C2BV08 HCC HlyC/CorC family transporter n=3 Tax=Mobilun...   282   1e-74
UniRef50_B0PH06 Putative uncharacterized protein n=1 Tax=Anaerot...   282   1e-74
UniRef50_C6D831 Putative uncharacterized protein n=6 Tax=Bacilla...   281   2e-74
UniRef50_B2UP23 Putative uncharacterized protein n=1 Tax=Akkerma...   281   2e-74
UniRef50_C1A9F4 Putative uncharacterized protein n=1 Tax=Gemmati...   281   2e-74
UniRef50_B3QY17 CBS domain containing protein n=1 Tax=Chloroherp...   281   2e-74
UniRef50_B0MM65 Putative uncharacterized protein n=1 Tax=Eubacte...   281   2e-74
UniRef50_C1YNF1 CBS domain-containing protein n=1 Tax=Nocardiops...   281   2e-74
UniRef50_C7PAX6 Putative uncharacterized protein n=1 Tax=Chitino...   281   2e-74
UniRef50_B5JS09 Magnesium and cobalt efflux protein CorB n=5 Tax...   280   3e-74
UniRef50_C1A944 Transporter n=1 Tax=Gemmatimonas aurantiaca T-27...   280   3e-74
UniRef50_C7HAW4 CBS domain protein n=2 Tax=Ruminococcaceae RepID...   280   3e-74
UniRef50_D2RTA7 Putative uncharacterized protein n=3 Tax=Haloter...   280   3e-74
UniRef50_B8FGS6 Putative uncharacterized protein n=1 Tax=Desulfa...   280   3e-74
UniRef50_UPI00016C05A3 CBS/transporter-associated domain protein...   280   3e-74
UniRef50_C0K042 Hemolysin-related protein n=1 Tax=uncultured bac...   280   3e-74
UniRef50_A8U4Z8 Hemolysin n=1 Tax=Carnobacterium sp. AT7 RepID=A...   280   4e-74
UniRef50_B2S3N8 Hemolysin n=5 Tax=Spirochaetaceae RepID=B2S3N8_T...   280   4e-74
UniRef50_O07589 UPF0053 protein yhdT n=119 Tax=Bacillales RepID=...   280   5e-74
UniRef50_UPI0000510515 magnesium and cobalt efflux protein n=1 T...   280   5e-74

Sequences not found previously or not previously below threshold:


CONVERGED!
>UniRef50_Q5SKB4 Hemolysin-related protein n=3 Tax=Thermus RepID=Q5SKB4_THET8
          Length = 445

 Score =  349 bits (896), Expect = 8e-95,   Method: Composition-based stats.
 Identities = 86/249 (34%), Positives = 144/249 (57%), Gaps = 1/249 (0%)

Query: 26  LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRN 85
                  + +EL  ++  + ++  I+    +M+  ++++ +  VR+IM PR +M+ ++  
Sbjct: 180 PRGTPLVSEEELKLILAGAEESGAIEPQEEEMIHSILELEETPVREIMTPRVEMVAIEDE 239

Query: 86  QTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-RSDAEAFSMDKVLRQAVV 144
            TL++ L +  E  +SR PV  E  DHI G+   +DLL +    D +AF +  +      
Sbjct: 240 ATLEDLLALYREHRYSRVPVYRESVDHIVGVAYVQDLLTYYCEEDLKAFKVASIAHPPYF 299

Query: 145 VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF 204
           VPE+     +LKE R ++ HMAIV+DEFGG +GLVT+ED++E IVGEI DE DE ++   
Sbjct: 300 VPENMDAWSLLKELRRRKVHMAIVVDEFGGTAGLVTLEDVIEEIVGEIYDESDEPEEHPI 359

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQF 264
           R L    ++++A   I++ +EA G    + E DT+ G +   FG +P+ GE+++  G++F
Sbjct: 360 RLLPDGAYSIQAQTPIDEVSEALGVELPEGEYDTLSGFLYALFGRIPSVGESLEWQGFRF 419

Query: 265 KVAMADSRR 273
            V  AD RR
Sbjct: 420 VVESADQRR 428


>UniRef50_B8G6A7 Putative uncharacterized protein n=3 Tax=Chloroflexus
           RepID=B8G6A7_CHLAD
          Length = 441

 Score =  343 bits (880), Expect = 6e-93,   Method: Composition-based stats.
 Identities = 83/283 (29%), Positives = 146/283 (51%), Gaps = 4/283 (1%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           ++ +   +L+       E    +++ AL+R+  +   ++   +  ++ V   +D+ VR I
Sbjct: 156 ASTRLILTLIGRANVEEERVTEEDIRALVREGAETGEVEPQEQQFIDRVFRFSDRAVRHI 215

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR ++  ++ N+TL E +D ++ S +SRFPV  E  D I GI+  +DLL   R   E 
Sbjct: 216 MTPRHEVEMVEANRTLGEVIDELLASGYSRFPVYEETPDQIVGIVHVRDLLLLYRKKGEQ 275

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             + + +   + VPE+ R   +L  FR  R HMA+V+ E GG+ G+VT+ED+LE IVGEI
Sbjct: 276 ALVREAVSPPLYVPENSRASALLTTFRRSRRHMALVVGELGGIEGVVTLEDVLEEIVGEI 335

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFG 248
           +DEYD+       +    ++ V     +++           DE+    +T+ GLV+   G
Sbjct: 336 DDEYDDATPPPIVRREDGSYLVEGSLPVDEVRALLEVDELPDEDTFRYETLAGLVISLIG 395

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           H+P  G+ +   G++F+V   D  R+ +V +     +  P   
Sbjct: 396 HIPTAGDVVRWSGWRFEVVDMDGLRVDKVLIARDSTTNHPSTS 438


>UniRef50_B8I559 Putative uncharacterized protein n=1 Tax=Clostridium cellulolyticum
           H10 RepID=B8I559_CLOCE
          Length = 434

 Score =  337 bits (867), Expect = 2e-91,   Method: Composition-based stats.
 Identities = 79/275 (28%), Positives = 148/275 (53%), Gaps = 5/275 (1%)

Query: 14  NKKGFFSLLLSQLFHG--EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +   F  +       G  E    +E+  ++    +  +I +  ++M++ + +  ++ V +
Sbjct: 160 STNFFIKVFGGNPAGGDDEKVTEEEIRMMMEVGEERGVIQDTEKEMIDNIFEFDNKSVSE 219

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM  R+ ++ +  +  ++  L ++    ++R P+ +++ D+I GIL  KDLL + +S  +
Sbjct: 220 IMTHRTNIVGIPVDSDINYVLYIMNRDKYTRVPIYNDNIDNIVGILHVKDLLEYTQSHNK 279

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            FS+ K++R A  VPESKR D + KE +  + H+A+VIDE+GG +G+VTIED+LE IVG 
Sbjct: 280 DFSLKKIIRSAYFVPESKRTDELFKEMQKNKVHLAVVIDEYGGTAGIVTIEDLLEEIVGN 339

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DEYD  +  D   L  +T+       ++   E        ++ DT+GG +++  G +P
Sbjct: 340 IFDEYDI-EQKDIEYLENNTYIFDGAIDLDKVEEVLDEDLPVDDFDTLGGFILKLLGRIP 398

Query: 252 ARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
              E  T+  +   FKV   + +RI++V     ++
Sbjct: 399 KVDEKPTVPYENIVFKVVKMEGKRIVKVQASKQEN 433


>UniRef50_Q1AX40 Putative uncharacterized protein n=1 Tax=Rubrobacter xylanophilus
           DSM 9941 RepID=Q1AX40_RUBXD
          Length = 442

 Score =  336 bits (864), Expect = 5e-91,   Method: Composition-based stats.
 Identities = 90/276 (32%), Positives = 150/276 (54%), Gaps = 2/276 (0%)

Query: 13  SNKKGFFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           ++          +L  G E  + +EL  +I  S  + ++D + RD L  V D  D+  R+
Sbjct: 164 ASTNLVLRPWGIRLGEGMEVHSEEELRIMISSSAASGVLDPEERDYLNNVFDFGDRVARE 223

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M+PR  ++ L  + +  E +       ++R+PV   D DH+ G++  KD+         
Sbjct: 224 VMVPRPDIVALSSDLSPQEMVQEAAFGRYTRYPVYEGDLDHVLGVVHVKDIFRASLESPG 283

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            F + K++R A+VVPE+K ++++L+EF+ ++  MAIVIDE+G V GLVTIED+LE IVGE
Sbjct: 284 GFDVRKIVRDALVVPENKPIEQLLREFQRRKLQMAIVIDEWGSVEGLVTIEDVLEEIVGE 343

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I+DE+D E++    +L    + V     I + NE F      E+ +TIGG V+   G  P
Sbjct: 344 IQDEFD-EEEARIEELGGGLYAVDGRIPIVEVNEFFELDLPHEDFETIGGYVLGTLGRPP 402

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             G+ ++ DG   +V   D  R+  + ++  + SP 
Sbjct: 403 RPGDVVEADGATLQVKSVDGPRVSMLTLRRKERSPS 438


>UniRef50_D1CDD2 CBS domain containing protein n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CDD2_THET1
          Length = 434

 Score =  336 bits (862), Expect = 7e-91,   Method: Composition-based stats.
 Identities = 102/283 (36%), Positives = 157/283 (55%), Gaps = 7/283 (2%)

Query: 15  KKGFFSLLLSQ-LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
              F  +   + +        D+L  L+    +  +I+++ RDM+ G++   D    ++M
Sbjct: 153 TNTFLGIFGVKDMPRNPFITEDDLRMLVNAGEEEGVIEQEERDMIAGILRFGDIAAHEVM 212

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           +PR  ++ +  N  L   LD+ +E  HSR PV  E  D++ GI+  KDL   + S +   
Sbjct: 213 VPRPDIVAVDVNTDLRTALDLALEKGHSRLPVYEESLDNVVGIVYLKDLARAIVS-SSNV 271

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           S+  + R AV +PESKR+  +L+EF+S + HMAIV+DE+GG +GL+TIEDILE IVGEI+
Sbjct: 272 SLRDLARPAVFIPESKRLGELLQEFQSSKVHMAIVVDEYGGTAGLITIEDILEEIVGEIQ 331

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DEYD E   D  ++S   W +RA   ++D NE  G H   EE DT+GG +      LP  
Sbjct: 332 DEYDVEL-PDIEKISEDEWIIRAKIDLDDVNELLGIHLPAEEYDTLGGFITAQLERLPVP 390

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPD----DSPQPKLDE 292
           G+ ++++G   KV   + RR+ +V VK          Q + DE
Sbjct: 391 GDEVEVEGVLMKVLDIEKRRVGRVLVKRLPVPTTSENQEEADE 433


>UniRef50_A9WFQ5 CBS domain containing protein n=4 Tax=Chloroflexaceae
           RepID=A9WFQ5_CHLAA
          Length = 450

 Score =  334 bits (859), Expect = 2e-90,   Method: Composition-based stats.
 Identities = 94/277 (33%), Positives = 143/277 (51%), Gaps = 2/277 (0%)

Query: 15  KKGFFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
            +  F+LL  Q     P    +EL  ++    +   I+ + R+M+EGVMD  D  VR+IM
Sbjct: 153 TRPIFTLLSGQPAPPTPLVTEEELRLMMSAGEKAGWIEHEEREMIEGVMDFGDTLVREIM 212

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR  ++ L+ N  L   LDV I   HSR PV  E  D++ GIL  KDL+P +R      
Sbjct: 213 IPRVDVVALEVNSPLKRALDVAITRGHSRIPVYEETIDNVVGILYVKDLIPVLRDGKHDT 272

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            +  +LR A  VP + +V  +L++ + +R HMAIV+DE+GG +G+VT+ED++E IVGEI 
Sbjct: 273 PLRDLLRPAYFVPVTMKVAALLEDLQRRRVHMAIVVDEYGGTAGIVTLEDLIEQIVGEIR 332

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DEYD E+     ++  +   V A   I+D        F +   D IGGLV +  G +P  
Sbjct: 333 DEYDTEEPA-IVEVGPNELIVDARVPIDDVAGLLEVEFPETTADRIGGLVYEQLGRIPRE 391

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           G+ +  +     V      R  ++ +     +     
Sbjct: 392 GDQVVCNDVTITVLSIKGIRAERLRIVRQAPAEITAA 428


>UniRef50_D2DIN9 CBS domain-containing protein n=1 Tax=uncultured Chloroflexi
           bacterium 1i19 RepID=D2DIN9_9CHLR
          Length = 455

 Score =  334 bits (857), Expect = 3e-90,   Method: Composition-based stats.
 Identities = 98/285 (34%), Positives = 159/285 (55%), Gaps = 11/285 (3%)

Query: 12  ISNKKGFFSLLLSQLFHGE--------PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMD 63
           ++        L S     E          + D L  LI       +I+ED + M+ G+ +
Sbjct: 138 LAPLSILLRRLASSARGDEDEVTAESVFLSEDGLRFLIHVGEGEGVIEEDEKQMIAGIFE 197

Query: 64  IADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL 123
             +  VR+IM+PR  ++ ++    L + LD+II + HSR PV  +  DH+ G+L AKDLL
Sbjct: 198 FGETTVREIMVPRLDIVAVEVTAPLSQALDLIIGNGHSRIPVYEDSIDHLLGVLYAKDLL 257

Query: 124 PFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIED 183
             +R  ++  S+ ++LR+A  VP+SK++D + +E ++ R HMA+ +DE+GG +GLVTIED
Sbjct: 258 LCLRDGSQDISVRQLLRKAYFVPQSKKLDELFEEMQAHRIHMALAVDEYGGTAGLVTIED 317

Query: 184 ILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD--EEVDTIGG 241
           +LE IVGEI+DEYD E+    ++L+   +   A   I++ +       S   E +DT+GG
Sbjct: 318 LLEEIVGEIQDEYDSEE-PQLKKLAPEIYIFNARYDIDEVSRLIDVDLSAGRENIDTLGG 376

Query: 242 LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
            +    G +P +GE+I    ++F V   DSRRI +V V+    + 
Sbjct: 377 FIYSQLGRVPEQGESIQFKDWRFTVLSVDSRRIEEVRVEPHHSAD 421


>UniRef50_D1N3F2 Putative uncharacterized protein n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N3F2_9BACT
          Length = 445

 Score =  334 bits (857), Expect = 3e-90,   Method: Composition-based stats.
 Identities = 81/281 (28%), Positives = 140/281 (49%), Gaps = 3/281 (1%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           ++      L    L + +    +E+  ++    +N  I+ D + M+E V +  +    ++
Sbjct: 166 ASVNFVLRLFGVTLGNSQEVTEEEIRMMVDIGEENGAIESDEKRMIENVFEFNNTTAAEV 225

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M  R++M+ L      +E   V++    SR PV  ED D I G L  ++ L        A
Sbjct: 226 MTHRTEMVALDIEAPPEEVEKVLMSCGFSRVPVYREDIDEIIGFLHFREYLSAKVQGNSA 285

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             + K+L+   + PE+ R + + +  +S+++ MAI++DEFGG SGLVTIED+LE IVG +
Sbjct: 286 PDIRKLLKPVYLAPETMRANILFRNMQSKKFGMAIILDEFGGTSGLVTIEDLLEEIVGSL 345

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DEYDE  DI+  QL    W +     +++ +        +EE DTIGGLV      +P 
Sbjct: 346 YDEYDEA-DIEIEQLGEGEWRIDGSMRLDEISRRLDLALPEEEYDTIGGLVFGMLNEVPT 404

Query: 253 RGETIDID--GYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
            G T+++   G   +V   + RR+ +V ++      +   +
Sbjct: 405 VGATVELPVSGISIRVESVEERRVDKVILQYTPPQEEESGE 445


>UniRef50_C1SMP1 CBS domain-containing protein n=1 Tax=Denitrovibrio acetiphilus DSM
           12809 RepID=C1SMP1_9BACT
          Length = 434

 Score =  332 bits (854), Expect = 7e-90,   Method: Composition-based stats.
 Identities = 109/279 (39%), Positives = 158/279 (56%), Gaps = 4/279 (1%)

Query: 16  KGFFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           KG   L   +L         DEL   I +S +  +I+     ML+ + DI++  V+++M+
Sbjct: 149 KGMIILSGGKLDRNKNQITEDELEFYICESEKEGIIENGKSRMLQNIFDISEIYVKEVMV 208

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR+ M+ +     ++  +D I  S  SR PV  E  D I GIL  KDLL F+  D+  F 
Sbjct: 209 PRTDMVAIDIEDPVESYIDKIHASEFSRIPVYEETIDKIIGILYVKDLLRFVNEDSTQFD 268

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           + KVLR+   +PE+K++D ML EF+  R HMAIVIDE+GGV GLVT+EDILE IVGEI D
Sbjct: 269 LRKVLRKPYFIPETKKIDSMLSEFQRNRNHMAIVIDEYGGVDGLVTLEDILEEIVGEIWD 328

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH--FSDEEVDTIGGLVMQAFGHLPA 252
           EYD E+  +  ++S +T+ V     I+DF E FG       +E +T+GGLV      +P 
Sbjct: 329 EYDTEEQ-EVTEISENTFIVDVRMDIDDFCEKFGLEKTHEMDEYETVGGLVFDIAEKIPE 387

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
            GE    + YQFK+     RR+ +V ++  +  P  K +
Sbjct: 388 VGEQYVYENYQFKILNKHERRLDKVELRRIEKEPDEKQE 426


>UniRef50_C7IJK2 CBS domain containing protein n=5 Tax=Firmicutes RepID=C7IJK2_9CLOT
          Length = 377

 Score =  331 bits (850), Expect = 2e-89,   Method: Composition-based stats.
 Identities = 84/275 (30%), Positives = 146/275 (53%), Gaps = 5/275 (1%)

Query: 14  NKKGFFSLLLSQLFHG--EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +   F  L       G  E    +E+  ++    +  +I +  ++M++ + +  ++ V +
Sbjct: 103 STNFFIKLFGGNPAGGDDEKVTEEEIRMMMEVGEERGVIQDSEKEMIDNIFEFDNKHVSE 162

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM  R+ +  +  +  L+  L V+    ++R PV SE+ D+I GIL  KDLL + +++A+
Sbjct: 163 IMTHRTDIDGIPVDSDLEYVLYVMNRDKYTRVPVYSENLDNIVGILHVKDLLEYTQNNAK 222

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            FS++K+ R A  VPESKR D + KE +  + H+A+VIDE+GG +G+VTIED+LE IVG 
Sbjct: 223 DFSLEKITRSAYFVPESKRTDELFKEMQKNKVHLAVVIDEYGGTAGIVTIEDLLEEIVGN 282

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DEYD  +  D   L   T+      S++   E        ++ DT+GG +++  G +P
Sbjct: 283 IFDEYDI-EQKDIEYLENDTYVFDGAISLDRVEEVLDEELPVDDFDTLGGFILKLLGRIP 341

Query: 252 ARGET--IDIDGYQFKVAMADSRRIIQVHVKIPDD 284
              E   +  +   F+V   +  RI +V     ++
Sbjct: 342 KVDEKPVVQYENIVFRVTEMEGMRIAKVQASKKEN 376


>UniRef50_B7IDY0 Integral membrane protein with CBS domains n=4 Tax=Thermotogaceae
           RepID=B7IDY0_THEAB
          Length = 430

 Score =  331 bits (849), Expect = 2e-89,   Method: Composition-based stats.
 Identities = 89/281 (31%), Positives = 157/281 (55%), Gaps = 5/281 (1%)

Query: 11  TISNKKGFFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
            +S       ++        P    ++++  +    +   I  +   ML+  +++ +  V
Sbjct: 150 LVSISNFVIRIIGGTYVEEAPFITTEDIIMYVEVGREEGTIKHEESFMLKRTLEMEESVV 209

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           R+IMIPR  ++ ++ ++TLD+ +++I E  +SR PV  E  D++ GI  AKD+L F+   
Sbjct: 210 REIMIPRVDIVAIEESETLDKVMEIIKEEEYSRIPVYKETIDNVVGICYAKDVLAFISDR 269

Query: 130 A----EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDIL 185
                E   + +++R+ + VPE+ +V  +LK F+ Q+ HMAIV+DE+GG +GLVT+EDIL
Sbjct: 270 GSEICEKVKVKELMREPLFVPETMKVSELLKIFKEQKMHMAIVVDEYGGTAGLVTMEDIL 329

Query: 186 ELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQ 245
           E I GEI DEYD+ +++  ++L   ++ V A   I D        F + + +T+ G +++
Sbjct: 330 EEIFGEIMDEYDQNENLGIKKLENGSYIVDATVPINDIERELKIEFPETDYETLAGYILE 389

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
               +P  GE I ID ++FK+  A   RI +V VK+  D+ 
Sbjct: 390 HLQRIPKVGEEIIIDKFKFKIIAASKNRIEKVLVKVVKDNE 430


>UniRef50_B8CXI7 Putative membrane CBS domain protein n=1 Tax=Halothermothrix orenii
           H 168 RepID=B8CXI7_HALOH
          Length = 420

 Score =  330 bits (848), Expect = 3e-89,   Method: Composition-based stats.
 Identities = 84/257 (32%), Positives = 140/257 (54%), Gaps = 2/257 (0%)

Query: 25  QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKR 84
            L   +  + +E+   +  S +  +I  D R M+  + +  D  V++IM+PR  M+ +K 
Sbjct: 153 DLLSSKLLSEEEIKRFVNVSEEEGVIKTDERRMINSIFEFDDTTVKEIMVPRIDMVCIKS 212

Query: 85  NQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVV 144
           +  L E + + ++  HSR PV     D I G++  KDLL ++        +   +R    
Sbjct: 213 DTELSEVIKIAVDRGHSRIPVYKNTIDEIIGVVYVKDLLGYLTKPENDARLADFIRSPYY 272

Query: 145 VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF 204
           VPESK+++ +L E + ++ HMAIV+DE+GG SGLVTIEDILE IVG+I+DEYD  +    
Sbjct: 273 VPESKKINELLTEMKKKKVHMAIVLDEYGGTSGLVTIEDILEEIVGDIQDEYDT-EPSQI 331

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
             ++     + A   I+D NE        +E+ +TI G ++   G++P  GE +++DG  
Sbjct: 332 EFINDKELLIDARVDIDDLNEILPEPLPGEEDYETISGFILHYLGYVPKTGEELELDGLH 391

Query: 264 FKVAMADSRRIIQVHVK 280
             V  +   +I +V +K
Sbjct: 392 ILVEESSKHQIKKVRLK 408


>UniRef50_D0MD79 CBS domain containing protein n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MD79_RHOM4
          Length = 421

 Score =  330 bits (847), Expect = 4e-89,   Method: Composition-based stats.
 Identities = 95/264 (35%), Positives = 153/264 (57%), Gaps = 6/264 (2%)

Query: 26  LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRN 85
                P + DEL AL  +  Q+ ++ ED R++L  +++  +  VR+IM+ R  ++ +   
Sbjct: 150 RAPERPLSPDELKAL--EVAQDGMLGEDERELLAAILEFGETTVREIMVSRLDIVAIPET 207

Query: 86  QTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM--RSDAEAFSMDKVLRQAV 143
            T  E L  I  S HSR P+ +E  D+I GI+ AKDLLP++      +  +   + R A+
Sbjct: 208 ATFGEVLACIRTSGHSRLPLYAEHLDNILGIVYAKDLLPYLGRAELDQPLNWRDIARPAM 267

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
            VP SKR+D +L++F+ ++ HMAIV+DE+GG +GLVT+ED+LE IVG+I DE+DE + + 
Sbjct: 268 FVPLSKRLDDLLRDFQRRKTHMAIVVDEYGGTAGLVTLEDVLEEIVGDIRDEHDETEPVL 327

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDE--EVDTIGGLVMQAFGHLPARGETIDIDG 261
           + QL  HT+ V A  +++D  E  G     E  + +T+GGL+    G +P  G+ +    
Sbjct: 328 YEQLDEHTYRVDARMNLDDLAELLGIELDTESFDFETLGGLIFHLLGVIPEPGDEVQYGP 387

Query: 262 YQFKVAMADSRRIIQVHVKIPDDS 285
              +V   D+ RI QV V++    
Sbjct: 388 LHLRVETVDNHRIGQVLVRVEPTP 411


>UniRef50_A5UY55 Putative uncharacterized protein n=3 Tax=Chloroflexi (class)
           RepID=A5UY55_ROSS1
          Length = 479

 Score =  327 bits (841), Expect = 2e-88,   Method: Composition-based stats.
 Identities = 86/277 (31%), Positives = 148/277 (53%), Gaps = 6/277 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           + +    LL        P   D+++AL+R+   +  + +  + ++  V   +D+ VR +M
Sbjct: 177 STEVVLRLLGRHNVAEMPVTEDDIMALVREGAADGTVADAEQTVIHNVFKFSDRTVRSLM 236

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR+Q+  L  +  ++E L +  ES +SR PV     DH+ GIL  KDLL F     E  
Sbjct: 237 TPRTQITALDVDTPIEEALRIATESGYSRIPVYEGSLDHVIGILYVKDLLAFW-GQCEPP 295

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           ++ ++LR  + V ES+R  +  ++ +  R  +AIV+DE+G V+G++TIED+LE +VG+I 
Sbjct: 296 NLRELLRPPMYVIESQRAAQAFQQLKQNRNALAIVLDEYGQVAGVITIEDMLEELVGDIS 355

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-----EVDTIGGLVMQAFG 248
           DEYD+E D    +    ++ V  L    D  E      +D+       +T+ G ++   G
Sbjct: 356 DEYDDETDESIVRRDDGSYLVDGLTPFADLRERLKLPPADDLVREHGFETLAGFLLALLG 415

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            +PA G+++  +GY F++   D RRI +V V  P  +
Sbjct: 416 RIPAVGDSVKWEGYSFEIVDMDGRRIDKVLVVPPRPA 452


>UniRef50_B2I8U5 CBS domain containing protein n=17 Tax=Xanthomonadaceae
           RepID=B2I8U5_XYLF2
          Length = 323

 Score =  327 bits (840), Expect = 2e-88,   Method: Composition-based stats.
 Identities = 128/291 (43%), Positives = 187/291 (64%), Gaps = 5/291 (1%)

Query: 1   MSDDNSHSSDTISN--KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDML 58
           MS+D+ H + T S   ++ +   L S  F G+P   D+L+ ++R +  + +I  DT  M+
Sbjct: 31  MSEDDDHRTITESQEKRRSWLERL-SAAFSGDPHTLDDLMVILRSAEHHGIIATDTLRMM 89

Query: 59  EGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILM 118
           EG + IAD  V D+M+PRSQM++L     L      ++ES HSRFPV  E+KD + GIL+
Sbjct: 90  EGAIAIADLTVGDVMVPRSQMVSLPVESDLQTITKQMVESGHSRFPVHGENKDEVLGILL 149

Query: 119 AKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           AKDLL  + ++    ++ ++LR   ++PESK+++ +LKEFR    HMAIV+DE+GGV+GL
Sbjct: 150 AKDLLRGVSANHTITNVHELLRPVGMIPESKKLNVLLKEFRLSHNHMAIVVDEYGGVAGL 209

Query: 179 VTIEDILELIVGEIEDEYDEEDDID--FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEV 236
           VTIEDILE IVG+I+DE+DE +D        +   + V AL  IEDFNE F   F D++ 
Sbjct: 210 VTIEDILEQIVGDIDDEHDETEDQTNMIAIQADGCYIVDALTPIEDFNERFNAEFPDDDY 269

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           DTIGGLV +A GHLP  G+ + I  + F+VA A++RRI  +HV +   + Q
Sbjct: 270 DTIGGLVTEAIGHLPETGDELTIGRFAFRVAKANARRIHILHVTVLPPNEQ 320


>UniRef50_B0PAE4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0PAE4_9FIRM
          Length = 472

 Score =  326 bits (838), Expect = 4e-88,   Method: Composition-based stats.
 Identities = 80/276 (28%), Positives = 146/276 (52%), Gaps = 6/276 (2%)

Query: 18  FFSLLLSQLFHGEP--KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
             S L       E      +E+  ++    +   I++  +DM+  + +  D+ V ++M  
Sbjct: 196 LLSRLFGARGGDETERVTEEEIRMMVDVGNEKGAIEQSEKDMINNIFEFDDRNVSEVMTH 255

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R+ M  + ++ T+D  + + IE+  SR PV  ED D I GI+  KDLL  + +    F  
Sbjct: 256 RTDMTAVPKDVTIDRIVAIAIETGFSRIPVYDEDIDDIMGIVYVKDLLCLIGTPGVDFDA 315

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
            K +R A+ VPES     +  +F+ ++  +AIV+DE+GG +G+ ++ED+LE IVG I+ +
Sbjct: 316 QKYMRPALFVPESMSCVDLFAQFKQKKVMVAIVVDEYGGTAGIASMEDLLESIVGNIQ-D 374

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARG 254
             +++D +  ++S   +T+    SIED    F     ++ E DTIGGL+++    +P+  
Sbjct: 375 EYDDEDEEICKMSDGVYTLDGAVSIEDVERLFDIELDEDSEYDTIGGLLIEKLERIPSPH 434

Query: 255 ET--IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           E   +++ G +F V + + RRI ++  + P    Q 
Sbjct: 435 EHPALELSGVRFTVLLVEDRRIARIRAEKPSAPGQE 470


>UniRef50_A7HLR9 Putative uncharacterized protein n=1 Tax=Fervidobacterium nodosum
           Rt17-B1 RepID=A7HLR9_FERNB
          Length = 443

 Score =  326 bits (838), Expect = 5e-88,   Method: Composition-based stats.
 Identities = 93/286 (32%), Positives = 154/286 (53%), Gaps = 5/286 (1%)

Query: 12  ISNKKGFFSLLLS-QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           ++    F  L    ++        D++ + +    +   ID +   M+E  + + +  V+
Sbjct: 148 VTVSNYFVKLFGGQKVAEAPFITMDDIASYLEMGREEGTIDHEEGLMVERTIAMDETLVK 207

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           +IMIPR  ++ ++  QTL E ++VIIE  +SR PV  +  D++ GI  AKD+L F+    
Sbjct: 208 EIMIPRIDVVAVEETQTLGEVINVIIEEEYSRIPVYRDTIDNVVGICYAKDILSFIAQRG 267

Query: 131 EAF----SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
                   + +++R  + VPE   V  +LKEF+S++ HMAIV+DE+GG +G+VT+EDILE
Sbjct: 268 SDVMNKVRVKELMRPPLFVPEVMPVSELLKEFKSKKVHMAIVVDEYGGTAGIVTMEDILE 327

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            I GEI DEYDE +    ++L   T+ V A  S+ D        F + E +T+ G ++  
Sbjct: 328 EIFGEIMDEYDEHESTGIKKLDDFTYLVDATLSLNDIERELRIEFPEGEFETLAGYLLDK 387

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           F H+P  GE  +     +KV  A   RI +V +KI  D  + + ++
Sbjct: 388 FHHIPKVGEQYEDSNITYKVVAASRNRIEKVLMKINVDIDKEEKND 433


>UniRef50_Q3A2F6 Uncharacterized CBS domain-containing protein n=2
           Tax=Desulfuromonadales RepID=Q3A2F6_PELCD
          Length = 417

 Score =  325 bits (835), Expect = 9e-88,   Method: Composition-based stats.
 Identities = 95/278 (34%), Positives = 163/278 (58%), Gaps = 2/278 (0%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
            +         L  +       + +E+  LI    Q+ ++ +D R ML+G+ D++   VR
Sbjct: 142 WLVTGFSRLLTLFVKSEPQPVISEEEIRTLITVGEQSGVVGKDKRKMLDGIFDLSQICVR 201

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           D+MIPR+++  L  + +  E L ++ +S+HSRFP+     D++ GI+ +KD+L ++    
Sbjct: 202 DVMIPRTEIAALDVSFSFAEVLRLVQQSSHSRFPIYEGSLDNVIGIIHSKDILRYVHISE 261

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           E FS++K+ R+   VPESKR++ +L  F+ ++ HMA+V+DE+GGV GLVT+ED++E IVG
Sbjct: 262 E-FSLEKLARKPYFVPESKRINTLLPAFQRRQVHMAVVVDEYGGVEGLVTLEDVVEEIVG 320

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           EI DEYD ++D+   +L    + + A  S+   N+ FG   S+E   T+ G ++   G +
Sbjct: 321 EIRDEYDIDEDM-VCELRPGRYLLDASISLRAVNQRFGLELSEEHASTLAGFLLGVLGSI 379

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           P  G++ ++D   F V      RI ++ + +P DSP P
Sbjct: 380 PRVGDSCEVDKSHFIVRKVIHHRIEEIELLLPPDSPDP 417


>UniRef50_Q47RN3 CBS domain protein n=1 Tax=Thermobifida fusca YX RepID=Q47RN3_THEFY
          Length = 439

 Score =  324 bits (832), Expect = 2e-87,   Method: Composition-based stats.
 Identities = 93/289 (32%), Positives = 145/289 (50%), Gaps = 11/289 (3%)

Query: 9   SDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
           +  +                G     +EL  L+  + +  +ID + R M+  V  + D  
Sbjct: 145 ARLLVRAGQLLLPRGGTDREGPFATEEELRHLVDLAERGHVIDPEERQMIHSVFQLDDTT 204

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS 128
           VR++MIPR  ++ L+ N +++E L+  + S +SR PVI E  D + GI+  KDL+  +  
Sbjct: 205 VREVMIPRPDIVFLEGNVSIEEALEKALSSGYSRIPVIGESLDDVIGIVYLKDLVARLYD 264

Query: 129 DAEA--------FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
              A         ++  V+R+   VP+SK VD +L+E + QR H+A+VIDE+GG +G+VT
Sbjct: 265 AWRANGGAPAPGRTIRDVMREPTYVPDSKPVDELLREMQQQRIHLAVVIDEYGGTAGIVT 324

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IEDI+E IVGEI DEYD+E       L  +   V A   + +  E FG      +VDT+G
Sbjct: 325 IEDIVEEIVGEITDEYDDEVPP-IEWLDDNRARVTARLPLGELAELFGVEIDAPDVDTVG 383

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRII--QVHVKIPDDSPQ 287
           GL+  A G +P  G   +  G +        RR     V V+    + +
Sbjct: 384 GLLAYALGRVPVPGSQAEYAGLRLVAEDPARRRRKTATVLVERLPAAVE 432


>UniRef50_A7NHB2 CBS domain containing protein n=1 Tax=Roseiflexus castenholzii DSM
           13941 RepID=A7NHB2_ROSCS
          Length = 435

 Score =  324 bits (831), Expect = 3e-87,   Method: Composition-based stats.
 Identities = 102/278 (36%), Positives = 161/278 (57%), Gaps = 8/278 (2%)

Query: 17  GFFSLLLSQLFHGEP------KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           G  +    ++  G+          +EL  L+    +  LI+ + R+M+EG+    D  VR
Sbjct: 145 GLLTRPFLRVASGQTTSSMPLVTEEELRMLVNVGEEEGLIEPEEREMIEGIFSFGDTTVR 204

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           ++MIPR  ++ L+   ++DE L++II + HSR PV  E  DHI GIL AKDLL ++RS  
Sbjct: 205 EVMIPRVDIVALEETASIDEALNIIITTGHSRIPVYRETIDHIVGILYAKDLLLWLRSGQ 264

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
              S+  +LR A  VP++ +VD +LK+ ++++ H+AIV+DE+GG +GL+TIED++E IVG
Sbjct: 265 RDASIGALLRTAHFVPDTMKVDALLKDLQARKIHLAIVVDEYGGTAGLITIEDVIEEIVG 324

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           EI+DEYD ++    R L+     V A   I+D N+  G   + EE D IGG+V +  G +
Sbjct: 325 EIQDEYDVDEQP-IRVLAPGDMEVDARVPIDDINDLTGLRLASEESDRIGGMVFERLGRV 383

Query: 251 PARGETIDI-DGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           P  G+T+ I DG    V   D  R+ ++ ++       
Sbjct: 384 PKVGDTVQIADGVTVVVLSMDGLRLRKLRLQYRLPQED 421


>UniRef50_D1B5K7 Putative uncharacterized protein n=1 Tax=Thermanaerovibrio
           acidaminovorans DSM 6589 RepID=D1B5K7_THEAS
          Length = 426

 Score =  324 bits (831), Expect = 3e-87,   Method: Composition-based stats.
 Identities = 86/263 (32%), Positives = 145/263 (55%), Gaps = 2/263 (0%)

Query: 22  LLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT 81
           +  +L       R+E+  ++++   +  ++E+ R M+ G++   + RV +IM+PR+ ++ 
Sbjct: 158 MGIRLDTASLVTREEIDHMVKEGSASGALEEEERKMIHGIISFEETRVSEIMVPRTDVVA 217

Query: 82  LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQ 141
           +    T+ + + + ++S HSR P+   D DH+ GIL  KDLL  +        ++   R 
Sbjct: 218 VVAGSTVRDAVRIFMDSGHSRMPIYEGDMDHVVGILYVKDLLRNLTQGDMDRPVEDCKRD 277

Query: 142 AVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD 201
            + VPE+ R+  +    +  R HMA+V+DE+GG +GLVT+ED+LE IVGEI+DEYDEE  
Sbjct: 278 CLFVPETMRIGELFDRMKKARVHMAVVVDEYGGTAGLVTLEDLLEEIVGEIQDEYDEEIP 337

Query: 202 IDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDG 261
               Q     + V+    +ED +EA G  F  E+VDT+ G V+   G  P  G+ I  D 
Sbjct: 338 P--IQEEGGVFVVQGHVHLEDLSEALGHQFQAEDVDTVAGFVLSILGAFPEEGQGILYDD 395

Query: 262 YQFKVAMADSRRIIQVHVKIPDD 284
           +  +V      RI++V  +  +D
Sbjct: 396 WSIEVTKVQGHRIMEVRFRRLED 418


>UniRef50_Q1IYV3 CBS domain-containing protein DUF21 n=4 Tax=Bacteria
           RepID=Q1IYV3_DEIGD
          Length = 446

 Score =  323 bits (830), Expect = 4e-87,   Method: Composition-based stats.
 Identities = 83/262 (31%), Positives = 141/262 (53%), Gaps = 5/262 (1%)

Query: 13  SNKKGFFSLLLSQLF--HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           +   G   L   Q    H    + +E+  ++  S Q  ++++D ++++  V D+++  VR
Sbjct: 159 ALGNGVVRLFGLQGVAGHHTAYSEEEIRMIVSASSQEGVLEDDEKELVYNVFDLSETTVR 218

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           ++M PR++M+T++    L   L++  E  +SR PV  +  D++ G+    D+L ++    
Sbjct: 219 EVMTPRTEMVTVEATCPLRRLLELNAEHGYSRVPVYQDSADNVVGVAHTSDVLRYLDRLD 278

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           E   +  V+     VPE  +++ +L + R ++ HMAIV+DEFGG SGLVT+ED LE IVG
Sbjct: 279 ETL-IADVMHPVFFVPEGMKINDLLAKMREKKSHMAIVVDEFGGTSGLVTLEDALEEIVG 337

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD--EEVDTIGGLVMQAFG 248
           EI DE DEE+      L    + + A  ++ +  E  GT+  D   E DT+ G +   FG
Sbjct: 338 EIYDETDEEEQPLIEVLGEGIYLMDASLTVGEVEERLGTNLEDGEGEYDTLSGFMTSHFG 397

Query: 249 HLPARGETIDIDGYQFKVAMAD 270
            +P  G++    G+ F V  AD
Sbjct: 398 DIPEIGQSFVYGGWAFTVVDAD 419


>UniRef50_C7GAD7 CBS domain protein n=9 Tax=Bacteria RepID=C7GAD7_9FIRM
          Length = 426

 Score =  322 bits (827), Expect = 9e-87,   Method: Composition-based stats.
 Identities = 91/280 (32%), Positives = 144/280 (51%), Gaps = 4/280 (1%)

Query: 15  KKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
             GF  LL      +      +EL  ++  S +N +I+ +  +M+  + D  D + +++M
Sbjct: 149 SMGFLFLLHVDPKANNNQMTEEELRTIVDVSKENGVIESEEHEMINNLFDFGDAQAKEVM 208

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR  M     N T DE +D+  E   +R PV  +  D++ GIL  KDLL  +  D E F
Sbjct: 209 IPRPDMTFANVNNTYDELIDIFQEDKFTRLPVYEDTTDNVIGILNMKDLL--LCKDKEHF 266

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           S+  ++R+     E K    +  E R     +AIV+DE+G  +GL+T+ED+LE IVGEI 
Sbjct: 267 SVRDIMREPYFTFEHKNTAELFIEMRKSSISLAIVLDEYGATAGLITLEDLLEEIVGEIR 326

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DEYD +++     L+   + V    +++D  +    +FS E+ DTIGG ++    HLP +
Sbjct: 327 DEYDTDEEDPILPLNDREFIVSGSTNLQDLCDELDLNFSSEDYDTIGGYLLGLLDHLPEK 386

Query: 254 GETIDI-DGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            E I   D    +V   D  RI +V++K PD  P     +
Sbjct: 387 NEIIITDDNVLLRVEQMDKNRIEKVYIKKPDFPPDESDKQ 426


>UniRef50_C5VQE4 CBS domain integral membrane protein n=9 Tax=Clostridiales
           RepID=C5VQE4_CLOBO
          Length = 429

 Score =  321 bits (824), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 80/275 (29%), Positives = 145/275 (52%), Gaps = 2/275 (0%)

Query: 15  KKGFFSLLLSQLFHGEPK-NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
                 +   +   G+P    +EL  ++  S +  +++ + R M+  V +  D +V+D+M
Sbjct: 149 TNKIVRIFGGRADMGKPHITEEELKTIVDVSHEEGVLEVEERKMIYNVFEFGDSQVKDVM 208

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           +PR++MI++  + T DE ++++ +   SR PV  +  D+I G+L  K L+ F  +  + F
Sbjct: 209 VPRTEMISIDVDSTYDEVIEILKKEQFSRMPVYKDSTDNIIGVLHIKRLV-FFDNSKDKF 267

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + K + +     E K    +  E R  R  M IV+DE+GG +G+VT+ED++E IVG+IE
Sbjct: 268 DIYKYMIKPYFTYEYKPTTELFDEMRKNRVAMTIVLDEYGGTAGMVTMEDLVEEIVGDIE 327

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DEYD E + + + +    + V+    I++ NE   T    E+ D+IGG V+   G  P +
Sbjct: 328 DEYDNEQNDEIKLIKEDEYIVKGSTKIDEVNEMLKTSIESEDFDSIGGFVIGEIGRFPKK 387

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           GE I+    +F +   D+ RI ++ +    +    
Sbjct: 388 GEVIEFGNIKFIIEEIDNNRIKKLKILKNSNLKPE 422


>UniRef50_B8G2E5 Putative uncharacterized protein n=3 Tax=Clostridiales
           RepID=B8G2E5_DESHD
          Length = 437

 Score =  321 bits (823), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 79/275 (28%), Positives = 144/275 (52%), Gaps = 4/275 (1%)

Query: 15  KKGFFSLLLSQLFHGE--PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
                 L      +        +EL  L+  S ++ ++D+    +L+ V + +D+ V ++
Sbjct: 152 ANLILKLGGISPANESDLAHTEEELRMLVDASQRHGILDKMEGKLLDNVFEFSDRVVSEV 211

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M+PR  M+ L    +++E L+ +  S H+R+P+  +DKD++ G++  +DLL    S++  
Sbjct: 212 MVPRQDMMCLYIQDSMEEVLETVKTSGHTRYPLCDDDKDNVIGLVHMRDLLSL--SESSV 269

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
            ++ ++ R  ++VPE   +  ++++ R QR H+A+V+DEFGG +G+VTIED++E +VGEI
Sbjct: 270 KNIGELKRDILIVPEGMPISHLVQKMRVQRTHLAVVVDEFGGTAGMVTIEDLIEELVGEI 329

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DE++  +  +  +     + +     ++D +E     F DE V TIGG V    G  P 
Sbjct: 330 YDEFESAEQAEIIKSGESEYLINGRVLLDDLSELLAVEFEDETVSTIGGFVFNRLGRKPV 389

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           +G+ ID   Y F V      RI +V          
Sbjct: 390 KGDRIDFMDYTFTVMEVVGFRITRVKASRRPAPDS 424


>UniRef50_Q74EV6 CBS domain protein n=9 Tax=Desulfuromonadales RepID=Q74EV6_GEOSL
          Length = 444

 Score =  321 bits (823), Expect = 3e-86,   Method: Composition-based stats.
 Identities = 86/281 (30%), Positives = 153/281 (54%), Gaps = 5/281 (1%)

Query: 14  NKKGFFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           + K   +++  +    +    R+E+  ++ +  +  +     ++ +  + D     VR++
Sbjct: 160 SNKAVLAMMGIKAEGSQAFVTREEVQHIVAEGHEAGVFSATEQEYIRNIFDFTHTCVREV 219

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M+PR++M+ L   +   E +  ++++ +SR+PV  E  +++ G +  KDLL    +D E 
Sbjct: 220 MVPRTRMVALDLARPRMELVREVLDNMYSRYPVYRESIENVVGFIHGKDLLGRTVTDPE- 278

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
           F+M+ ++R    VPE K+V+ +LKE +  R HMA+V+DE+GG+SGLVT ED+LE +VGEI
Sbjct: 279 FAMESIVRPPFYVPEGKKVNELLKEMQRLRIHMALVVDEYGGISGLVTTEDLLEELVGEI 338

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLP 251
           EDE+D  +    ++L   +  V AL SI D  +       ++   DT+ GL++   G  P
Sbjct: 339 EDEHDIGEPGTVQRLPDGSLLVDALMSIGDLADLLKIKLEEDVPYDTLAGLILDQLGRFP 398

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            RGET++ D +           I  V V+I ++ P    DE
Sbjct: 399 ERGETVEWDRFSLICEEVKQTAI--VKVRIVENLPPQAGDE 437


>UniRef50_C1TQS8 CBS domain-containing protein n=2 Tax=Synergistaceae
           RepID=C1TQS8_9BACT
          Length = 425

 Score =  321 bits (823), Expect = 3e-86,   Method: Composition-based stats.
 Identities = 79/261 (30%), Positives = 143/261 (54%), Gaps = 1/261 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
             R+E+  ++     +  ++E  R M+ G++   D +V ++M+PR  M  +  + T++E 
Sbjct: 166 VTREEIEQVVTIGEASGALEESERRMIHGIISFEDTKVSEVMVPRIDMDVVDSDITIEEL 225

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           +  + E  HSR P+  +  D I GIL  KDL+  + S      +  + R A+ VPE+ +V
Sbjct: 226 IPHLEEHGHSRIPIYEDSLDDIIGILYVKDLIGLLYSGKTEVKLASLKRDALFVPETMKV 285

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
             +    +S+R HMA+V+DE+GG +G++T+ED+LE IVGEI+DEYD E      ++    
Sbjct: 286 PDLFNIMKSRRIHMAVVVDEYGGTAGIITLEDLLEEIVGEIQDEYDHELPA-IEEVEEGV 344

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           + V+    +ED ++  G  F  E+V+++GGL+    G  P  G ++    ++F V     
Sbjct: 345 YQVQGNMDLEDLSDFLGYPFESEDVESVGGLITDLSGDFPGTGSSVTYGPWEFTVLSLAD 404

Query: 272 RRIIQVHVKIPDDSPQPKLDE 292
            R+++V ++  D     + D+
Sbjct: 405 HRVMEVELRKIDSEECVEDDD 425


>UniRef50_D2LWG5 Putative uncharacterized protein n=3 Tax=Bacillus
           RepID=D2LWG5_BACS4
          Length = 415

 Score =  320 bits (821), Expect = 5e-86,   Method: Composition-based stats.
 Identities = 91/264 (34%), Positives = 139/264 (52%), Gaps = 1/264 (0%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           F S L+ +         +EL  LI  S +  +IDE  R+++   +D  D  V +I+ PR 
Sbjct: 152 FVSKLIKKEKTAPSVTEEELKELISISEEEGVIDESERELVHRSLDFNDIIVAEIVTPRM 211

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            ++ +  N T+DE  +  I+  +SR PV   + D+I GIL  +D L           + K
Sbjct: 212 DIVAIDVNNTVDEIKNTFIKERYSRIPVYEGNIDNIIGILSERDFLKAYIQLEYDVDIRK 271

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
           +LR  V V ES R+  +L + +  + HMAIVIDE+GG  GL+T+EDILE IVGEI DE+D
Sbjct: 272 LLRDPVFVFESMRIHTLLPQLQKNKGHMAIVIDEYGGTEGLITLEDILEEIVGEIWDEHD 331

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
           E+ ++  +Q+   T  V A   ++DF         D    TIGG + + F  +P+  E +
Sbjct: 332 EDINL-LKQVDPSTLIVHADCPLDDFVRKTKIELPDTPYHTIGGWLSEVFQRIPSVNEEV 390

Query: 258 DIDGYQFKVAMADSRRIIQVHVKI 281
             +    K+  AD RRI  + V +
Sbjct: 391 QYEHISLKIIDADERRIRAIEVSL 414


>UniRef50_A4VQY6 Metal ion transporter, putative n=2 Tax=Gammaproteobacteria
           RepID=A4VQY6_PSEU5
          Length = 280

 Score =  319 bits (820), Expect = 5e-86,   Method: Composition-based stats.
 Identities = 139/286 (48%), Positives = 198/286 (69%), Gaps = 7/286 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S     IS +K +    ++Q F  EPKNR ELL ++R++ QN L+D +   ++EG
Sbjct: 1   MSEDRS-----ISGQKTWLER-ITQAFAHEPKNRQELLEILREAHQNKLLDNEALAIVEG 54

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            + +AD +VRDIM+PRSQ+I++K +Q+  E L  II +AHSR+PV+ E  D + G+L+AK
Sbjct: 55  AIQVADLQVRDIMVPRSQVISIKADQSPREFLPAIIAAAHSRYPVVGESLDEVIGVLLAK 114

Query: 121 DLLPF-MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLLP  ++ D + F +  +LR A  VPESKR++ +L+EFR+   HMAIVIDE+GGV+GLV
Sbjct: 115 DLLPLILKEDQQNFDIKDLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLV 174

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVG+IEDE+D E+D   R L    + V+AL  I+ FNE FG+ F D+E DT+
Sbjct: 175 TIEDVLEQIVGDIEDEHDVEEDSYIRPLPSGDFLVKALTPIDSFNEYFGSAFPDDEFDTV 234

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            GLVM  FGHLP R E  +IDG++ +V  ADSRR+  + +   + +
Sbjct: 235 AGLVMSTFGHLPKRNEVTEIDGFRVRVLNADSRRVHMLRLSRLESA 280


>UniRef50_C6L9Q9 CBS domain protein n=6 Tax=Clostridiales RepID=C6L9Q9_9FIRM
          Length = 424

 Score =  319 bits (819), Expect = 7e-86,   Method: Composition-based stats.
 Identities = 87/278 (31%), Positives = 148/278 (53%), Gaps = 5/278 (1%)

Query: 15  KKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
                 LL       G+    +EL   +  S ++ +I+++ + M+  V D  D + +DIM
Sbjct: 149 SNLLIRLLGVDPNAKGDVMTENELRTYVDVSHEDGVIEQEEKQMIYNVFDFGDTQAKDIM 208

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR +M+++  N +  E L V  E   +R PV  E  D++ G+L  KD + F   D  +F
Sbjct: 209 IPRVEMVSIDVNASYQEVLKVFREEKFTRLPVYEESTDNVIGVLNIKDFIFF---DENSF 265

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            M  ++R+     E K    ++ + R    +  IV+DE+G  +GL+T+ED+LE IVGEI 
Sbjct: 266 DMRSMMREPNFTYEYKSTSELMDQMRQSSVNFTIVLDEYGATAGLITLEDLLEEIVGEIR 325

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DEYD++++   +++S   + +     ++D N+A       E+ D+IGGL++    HLPA 
Sbjct: 326 DEYDKDEEELIKKISDREYILPGFMKLDDVNDALDLLLHSEDYDSIGGLIIGELDHLPAV 385

Query: 254 GETIDI-DGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           GE++   DG +  V   D  RI QVH+ +P+   + + 
Sbjct: 386 GESVTTPDGIRLVVEAVDKNRINQVHLYLPEKKEETEE 423


>UniRef50_Q3JVV5 Magnesium and cobalt efflux protein CorC n=105 Tax=Proteobacteria
           RepID=Q3JVV5_BURP1
          Length = 403

 Score =  318 bits (817), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 124/286 (43%), Positives = 184/286 (64%), Gaps = 6/286 (2%)

Query: 1   MSD--DNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDML 58
           M+D   +  SSD    K+     L + +   EP +R ELL +++D+ + +LID D+  M+
Sbjct: 109 MNDSYPSRKSSDKPHEKRSLLERL-TDIISPEPDSRAELLEILQDAHERNLIDADSLSMI 167

Query: 59  EGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILM 118
           EGV  ++D   RDIM+PR+QM  L      ++ +  ++E AHSR+PV  +++D++ G+L+
Sbjct: 168 EGVFQVSDLCARDIMVPRAQMDALNIADKPEDFIPFVLEKAHSRYPVYEDNRDNVIGVLL 227

Query: 119 AKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           AKDLL F     E F +  +LR AV +PESKR++ +L +FR  R H+AIV+DE+GGV+GL
Sbjct: 228 AKDLLRFYAE--EEFDVRGMLRPAVFIPESKRLNVLLHDFRVNRNHLAIVVDEYGGVAGL 285

Query: 179 VTIEDILELIVGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           +TIED+LE IVG+IEDEYD +E+  +        + VRAL  IE FNE FGT FSD+EVD
Sbjct: 286 ITIEDVLEQIVGDIEDEYDFDEEAGNIIAAPDGRYRVRALTEIEQFNETFGTDFSDDEVD 345

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           TIGGL+   FG +P RGE + +    F++   D+R+I  + V+   
Sbjct: 346 TIGGLITHHFGRVPHRGEKVRLGELLFEIQRGDARQIHVLLVRRAP 391


>UniRef50_D1Y8K6 CBS/transporter domain protein n=1 Tax=Pyramidobacter piscolens
           W5455 RepID=D1Y8K6_9BACT
          Length = 421

 Score =  318 bits (817), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 90/261 (34%), Positives = 155/261 (59%), Gaps = 1/261 (0%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
                 ++E+  +++    +  I+E  R M++GV+   + RV +IMIPR++M  ++  +T
Sbjct: 162 KDSFVTKEEIGQVVKIGEASGAIEESERQMIDGVISFDEIRVSEIMIPRTRMHMIESERT 221

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPE 147
           +D+ L  I +   SR PV ++  D IEGI++ KDLL  +    +   + K +R  + VPE
Sbjct: 222 VDDALQFIEKMGDSRVPVFTDTPDRIEGIVLVKDLLTALMKGQKNAPVTKFMRTPLFVPE 281

Query: 148 SKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQL 207
           +  V ++ +  ++ R HMA+V+DE+GG +GL+T+ED+LE IVGEI+DEYD+E+      L
Sbjct: 282 TMYVPKLFRIMQNVRMHMAVVVDEYGGTAGLITLEDLLEEIVGEIQDEYDKEEQT-VTPL 340

Query: 208 SRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
           S  T+  +A   +E+ N+   +HF  ++VDT+GG ++  FG+ P  G+T+  DG+ F++A
Sbjct: 341 SDGTYRAKASIPLEELNDVLNSHFVCDDVDTLGGFLLDRFGNFPHEGDTLASDGWLFEIA 400

Query: 268 MADSRRIIQVHVKIPDDSPQP 288
             D  RI  V ++        
Sbjct: 401 SMDGHRINDVMIRRNSSEAGE 421


>UniRef50_B9KAC3 Hemolysin-related protein n=1 Tax=Thermotoga neapolitana DSM 4359
           RepID=B9KAC3_THENN
          Length = 466

 Score =  316 bits (812), Expect = 5e-85,   Method: Composition-based stats.
 Identities = 75/274 (27%), Positives = 149/274 (54%), Gaps = 5/274 (1%)

Query: 15  KKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
             G  +L   +    +     ++++++++  G+  +I+++   +++   ++    V++IM
Sbjct: 171 SDGIIALRHGKKISEDLFITEEDIVSIVQVGGEMGVIEQEEERIVKRAFEMKQIAVKEIM 230

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--- 130
            PR  ++ ++ NQT+ + +++I +  +SR PV  E  D+I G+  AKD+L  +       
Sbjct: 231 TPRVDIVAIEENQTVRDLIELIEDEGYSRIPVYRETIDNIVGVCYAKDVLSILAEKDCEE 290

Query: 131 -EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            +   +  ++R A+ VPE+  +D +LK  +S++ H+AIV+DE+GG +G+VT+EDI+E + 
Sbjct: 291 VKNMKVKDIMRDALYVPETMNIDELLKILKSKKIHIAIVVDEYGGTAGIVTLEDIIEELF 350

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G+I DEYD ++    +++   T+ V     I D        F   E +TI G +++ F  
Sbjct: 351 GDIMDEYDYDEVSGIKKIGEKTYIVDGSTPINDLEIELRIQFPQTEYETIAGYLLEHFKR 410

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           +P  GE   I    FKV      RI ++ +K+ +
Sbjct: 411 IPNVGEEAVIGNLYFKVLAVGKNRIEKIMIKVLE 444


>UniRef50_Q48DN5 Metal ion transporter, putative n=16 Tax=Proteobacteria
           RepID=Q48DN5_PSE14
          Length = 280

 Score =  316 bits (810), Expect = 7e-85,   Method: Composition-based stats.
 Identities = 142/286 (49%), Positives = 194/286 (67%), Gaps = 7/286 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S +       K +   L     H EPKNR ELL L+R++ QN L+D +   ++EG
Sbjct: 1   MSEDRSSNGQ-----KSWLGKLTQAFVH-EPKNRQELLELLREAHQNKLLDSEALAIVEG 54

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            + +AD +VRDIM+PRSQMI++K  QT  E L  +I++AHSR+PVI E  D + G+L+AK
Sbjct: 55  AIQVADLQVRDIMVPRSQMISIKATQTPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAK 114

Query: 121 DLLPFMRS-DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLLP +   D ++  + K+LR A  VPESKR++ +L+EFR+   HMAIVIDE+GGV+GLV
Sbjct: 115 DLLPLILKADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLV 174

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVG+IEDE+D E+D   + L    + V+AL  +E+FNE F + FSD+E DT+
Sbjct: 175 TIEDVLEQIVGDIEDEHDVEEDSYIKPLPSGDFLVKALTPVENFNEFFDSAFSDDEFDTV 234

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           GGLVM AFGHLP R E  +I  Y+F++  ADSRRI  + V      
Sbjct: 235 GGLVMNAFGHLPKRNEITEIGAYRFRILSADSRRIHLLRVTPISRP 280


>UniRef50_Q2JP27 Putative transporter, HlyC/CorC (HCC) family n=2 Tax=Synechococcus
           RepID=Q2JP27_SYNJB
          Length = 480

 Score =  316 bits (810), Expect = 8e-85,   Method: Composition-based stats.
 Identities = 77/284 (27%), Positives = 141/284 (49%), Gaps = 8/284 (2%)

Query: 14  NKKGFFSLLLSQLFHG----EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           + +    +L  ++            +EL  LI  S ++  I+ + R++L  + +  +   
Sbjct: 183 SSRCVLRILGVRIPEATSFYSTMTVEELQLLIASSVESGNIEAEERELLSNIFEFGETVA 242

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
            ++MIPR+ +  +    T+ E L  + ES HSR+PV  E  D I G++  K+L+  +   
Sbjct: 243 SEVMIPRTSIDAVPETATVQEVLAEVAESGHSRYPVYGESLDDIRGLIHVKELIGQLAKG 302

Query: 130 AEAF--SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
           +      +   +R+A   PE+K +  +L E R   + M +V+DEFGG +GL+TI+D++E 
Sbjct: 303 SIDLHSPITPFIREAHFEPENKPIAELLPEMRQHHWPMVVVVDEFGGTAGLITIQDLVEE 362

Query: 188 IVGEIEDEYDEE-DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQ 245
           IVG++ D  D    + D ++L  +T  ++A   IE+ NE  G +    E+  T+GG ++ 
Sbjct: 363 IVGKLSDGPDPNTKEPDIQELDENTLLIQAQLDIEEINERCGLNLPLHEDYQTLGGFLIY 422

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
               +P  GE       +F+V   +  R+ +V V     +P   
Sbjct: 423 HMQKIPRAGEKFTYQEMEFQVVRMEGPRVDRVKVARRPGTPANS 466


>UniRef50_A9BGT5 Putative uncharacterized protein n=1 Tax=Petrotoga mobilis SJ95
           RepID=A9BGT5_PETMO
          Length = 448

 Score =  315 bits (809), Expect = 1e-84,   Method: Composition-based stats.
 Identities = 72/285 (25%), Positives = 144/285 (50%), Gaps = 8/285 (2%)

Query: 15  KKGFFSLLLSQLFHGEP--KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
              F  L   +     P     DE+++ +    +  +I++  + +++  +++ D  V++I
Sbjct: 156 TNVFIKLFGGETITNAPPLITEDEIISYLDIGHEEGVIEKSEKYLMQRSLEMKDTSVKEI 215

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR  ++ ++  +T++E + +I E  +SR PV  E  D++ GI+ AKD+   +    + 
Sbjct: 216 MTPRVDILAIEDTKTMEELIKIINEEGYSRIPVFKETLDNVIGIVYAKDIFKKLDEVKDF 275

Query: 133 FSMD-----KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
             +      +++ +   VP + ++  + + F +   HMAIV+DE+GG +GLVT+EDI+E 
Sbjct: 276 TKLQKLRVVEIMHKPFFVPITMKIRDVFRLFLNNHTHMAIVVDEYGGTAGLVTLEDIIEE 335

Query: 188 IVGEIEDEYDE-EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
           + GEI DEYD+  D+ +  +++ +   V     I D        F + E +TIGG +++ 
Sbjct: 336 MTGEIFDEYDDYSDETNIIRVAENVILVDGTTPINDVERELDIEFPETEFETIGGFLLER 395

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           F   P  GE   I+  +F++      +I +V + +         +
Sbjct: 396 FKRFPKPGEIYYIENIEFEIVSVTINKIDKVKITVHPKMQTENQE 440


>UniRef50_A9KQ60 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A9KQ60_CLOPH
          Length = 429

 Score =  315 bits (808), Expect = 1e-84,   Method: Composition-based stats.
 Identities = 81/267 (30%), Positives = 138/267 (51%), Gaps = 1/267 (0%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
            F L +           +EL  ++  S +  +I+ + R M+  V+D  D   +D+M+PR 
Sbjct: 152 LFILRVDPNKKYVTMTENELRTIVDVSHEEGVIESEERKMITNVVDFGDSLAKDVMVPRI 211

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            M     + +  + ++V  E  +SR PV  E++D I GI+  KD+  F R D   F++  
Sbjct: 212 NMAFASVDMSYSQLIEVFREEQYSRMPVYDENRDDIVGIINLKDVF-FFRGDYNEFNIRD 270

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
            +R+     E K+   +L E + +   M IV+DE+G  +GL+T+ED+LE IVGEI DEYD
Sbjct: 271 YMREPYYTYEYKKTSELLSEMKRESLPMVIVLDEYGATAGLITMEDLLEEIVGEIRDEYD 330

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
            +++    +L  + +     A +++ NE  G     E+ D+I G ++    HLP + E I
Sbjct: 331 YDEEDVITKLGENEYLADGSAKLDEINEFIGLSLDSEDYDSIAGHIIHLLDHLPEQDEQI 390

Query: 258 DIDGYQFKVAMADSRRIIQVHVKIPDD 284
             +   + V   +  RI +VH+KI  +
Sbjct: 391 TENNITYTVTKVEKNRIDKVHIKIEPE 417


>UniRef50_Q3SVM7 Mg2+ and Co2+ transporter CorB family n=15 Tax=Alphaproteobacteria
           RepID=Q3SVM7_NITWN
          Length = 449

 Score =  315 bits (808), Expect = 1e-84,   Method: Composition-based stats.
 Identities = 80/275 (29%), Positives = 139/275 (50%), Gaps = 5/275 (1%)

Query: 13  SNKKGFFSLLLSQ-LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           S  +     L  + +   +     E+  LI +S ++  I+    + ++ V    D  V D
Sbjct: 159 SASRAILRALRVKEVSQHDVLTGAEIEGLIGESAEHGGIESGEAEYIQNVFRFGDLAVSD 218

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS--- 128
           +M+ R+ M+T+  +   ++ +  ++ S ++R P+  +  ++I G+L AKDLL  + +   
Sbjct: 219 VMVHRTAMVTINADLPPEDLVREVLASEYTRIPLWRDKPENIVGVLHAKDLLRAIHASEG 278

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           D    +++ +      VPE + V   LK FR ++ H A+V+DE+G V G+VT+ED+LE I
Sbjct: 279 DIARINVNAIALPPWFVPEMRPVSDQLKAFRRRKTHFALVVDEYGEVEGMVTLEDVLEEI 338

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VG+I DE+D       RQ +  +  V     I D N A   H  DEE  TI GLV+    
Sbjct: 339 VGDISDEHDVV-VAGVRQQADGSVVVDGSVPIRDLNRAMDWHLPDEEATTIAGLVIHEAR 397

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
            +P RG+     G++F+V   +  RI  + ++   
Sbjct: 398 SIPERGQNFTFYGFRFRVLRRERNRITALRIQPVP 432


>UniRef50_A1WVF4 CBS domain containing protein n=2 Tax=Ectothiorhodospiraceae
           RepID=A1WVF4_HALHL
          Length = 291

 Score =  314 bits (807), Expect = 2e-84,   Method: Composition-based stats.
 Identities = 121/290 (41%), Positives = 179/290 (61%), Gaps = 1/290 (0%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M D  ++SS+       +   L   +   EP++RDEL+  +R S    L+D D   M+EG
Sbjct: 1   MPDGEANSSNGAGESVSWRDRLRRLVTQVEPRSRDELVDHLRRSQSVGLLDADALSMIEG 60

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V+ +++ + RDIMIPRSQ+ T+ R+    + L  I+ + +SRFPV  E KD + GIL+AK
Sbjct: 61  VLHVSELQARDIMIPRSQVTTVARDTAPHDLLPTIVRTGYSRFPVTGESKDDVIGILLAK 120

Query: 121 DLLP-FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLL  F       F + +VLR  + +PESKR+D +LK+FR  R HM++V+DE+GG++G+V
Sbjct: 121 DLLRLFYEEGHNGFRLREVLRPVLFIPESKRLDALLKQFRESRNHMSVVVDEYGGLAGIV 180

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED++E IVGEI+DE+D ++D         +W V+A+  IE FNEA      ++++DT+
Sbjct: 181 TIEDVIEQIVGEIDDEHDFDEDAPILARDDGSWIVKAVTPIEAFNEALSAGLKEDDLDTV 240

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           GGLV Q FGH+P RGE I   G++F+V  AD RRI  + V          
Sbjct: 241 GGLVAQRFGHVPCRGERIVFAGFEFRVLRADQRRIHLLRVMPVGSEGHED 290


>UniRef50_B5YFP5 CBS domain protein n=1 Tax=Thermodesulfovibrio yellowstonii DSM
           11347 RepID=B5YFP5_THEYD
          Length = 432

 Score =  314 bits (805), Expect = 3e-84,   Method: Composition-based stats.
 Identities = 87/267 (32%), Positives = 151/267 (56%), Gaps = 4/267 (1%)

Query: 14  NKKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +          + F      +++EL  LI +  +  + + D R ++      A+  V++I
Sbjct: 159 STNFLLKPFGLRAFSQRGFISQEELKLLIEEGEEKGIFEPDERQLIHSAFSFAEITVKEI 218

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M+P  QM+T+    +++E  ++I++   SR+P + +D + I GIL AKD    +  + + 
Sbjct: 219 MVPAPQMVTVSIYMSVNEIKEIIMDEKFSRYPALGKDLNDIRGILHAKDFYNALIKNPDL 278

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             + ++L+  + VPE+ +++ +LKE + +R HMAIV+DE+G V+GLVT+EDILE +VGEI
Sbjct: 279 LDIKRLLKPPMFVPETMKINILLKEMQKKRVHMAIVVDEYGVVTGLVTLEDILEELVGEI 338

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLP 251
            DEYD E  +    L   +  + A  SI D  E +G    + EE DT+GG ++ +   +P
Sbjct: 339 RDEYDIE--MPVITLPDGSMIIDATISIRDLKEDYGIEIEESEEYDTLGGFILTSLQRIP 396

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVH 278
             G+T+D+DG  FKV     +RI ++ 
Sbjct: 397 HVGDTVDMDGKIFKVIEMVGQRISKIK 423


>UniRef50_C7LZP2 CBS domain containing protein n=1 Tax=Acidimicrobium ferrooxidans
           DSM 10331 RepID=C7LZP2_ACIFD
          Length = 420

 Score =  313 bits (804), Expect = 4e-84,   Method: Composition-based stats.
 Identities = 91/267 (34%), Positives = 148/267 (55%), Gaps = 1/267 (0%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
              +LL      G   +  ELLA+   + Q D+I+ D R+++  V+   D   R++M+PR
Sbjct: 149 SLSALLTPWRAPGATVSEAELLAMADAAEQGDVIETDERELIHSVISFGDTIAREVMVPR 208

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
             ++ +    T+   ++V+IE   SR PV     D++ GI++AKDLL    +      + 
Sbjct: 209 PDVVAVPAETTVAGAIEVVIEVGRSRLPVYESSLDNVLGIVLAKDLLALEHTGLRDVPVG 268

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
           + +R    VPE+K V  +LKE R  ++H+A+V+DE+G  +G+VT+ED++E +VGEI DE+
Sbjct: 269 QHMRPIHFVPETKPVADLLKEMRDGKFHLAVVVDEYGSTAGIVTLEDLIEELVGEIHDEF 328

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           D   +    +L    W VR   SI+D +E  G    + E D++GGL+M   GHLP  GE 
Sbjct: 329 DAGGE-GVVELGEGRWEVRGSVSIDDLSERIGEELPEGEWDSVGGLIMGLLGHLPRVGEE 387

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPD 283
           +D+DG + +V      R+  V V+   
Sbjct: 388 VDVDGVRLQVRQVARHRVASVLVERHP 414


>UniRef50_C1ZDU6 CBS domain-containing protein n=1 Tax=Planctomyces limnophilus DSM
           3776 RepID=C1ZDU6_PLALI
          Length = 439

 Score =  313 bits (804), Expect = 4e-84,   Method: Composition-based stats.
 Identities = 86/291 (29%), Positives = 155/291 (53%), Gaps = 12/291 (4%)

Query: 12  ISNKKGFFSLLLSQLFH-------GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDI 64
           + +   +   +  +L               DE+  ++ +  +   +++  R M+  VM++
Sbjct: 145 LLSLAKWLDRMAHRLVGRGEPEEDDASVLSDEIRTVVDEGQREGYLEQGARVMIHRVMEL 204

Query: 65  ADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP 124
            D+ V  IM PR+ M ++    +L+E    +I S HSR PV+++  D I G+L +KDLL 
Sbjct: 205 QDEDVGGIMTPRTDMFSIPLGASLEEARQKLISSGHSRVPVVADSPDEIVGLLYSKDLLK 264

Query: 125 FMR---SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
            +    +      + ++LR+   +PE+  +  +L+  + + + +AIV+DE+GGV+GLVT+
Sbjct: 265 ALDPACARDSLPKLSEILREPKYIPETTGIAALLEMMQREHFQLAIVLDEYGGVAGLVTM 324

Query: 182 EDILELIVGEIEDEYDE-EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTI 239
           EDILE IVGEI DEYD  E +   ++++ +   + A   I+D NE F     ++ E DTI
Sbjct: 325 EDILEEIVGEIADEYDTLEGESPVKKIAPNIVEIDARMHIDDLNEQFLYGLPEDGEFDTI 384

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           GG V    G +P+ GE  D +  +  +  AD R+I+++ ++ P +      
Sbjct: 385 GGFVFSQLGRMPSTGEIFDWNNLKMTIIEADKRKILRLRIEQPSEVTTESS 435


>UniRef50_Q72A49 CBS/transporter associated domain protein n=4 Tax=Desulfovibrio
           vulgaris RepID=Q72A49_DESVH
          Length = 464

 Score =  313 bits (803), Expect = 5e-84,   Method: Composition-based stats.
 Identities = 77/289 (26%), Positives = 145/289 (50%), Gaps = 14/289 (4%)

Query: 12  ISNKKGFFSLLLSQLFH--------GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMD 63
           +S    +   L S+           G     +++  ++ +  ++ ++ +  R M E VM 
Sbjct: 151 LSMPAVWLLSLSSRAASTILRIREDGPSVTDEDIRGMLAEGVRSGVVLDAERTMSERVMR 210

Query: 64  IADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL 123
           + D+ V  IM  R+++  L      ++ ++ +  S +SRFPV   D D++ G++ A++ L
Sbjct: 211 LGDRSVTSIMTHRTRVAWLDSEAPQEDIIERLAASTYSRFPVCDGDLDNVLGVIKAREYL 270

Query: 124 PFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQ-RYHMAIVIDEFGGVSGLVTIE 182
                 A+  ++   +RQ V +PE+ R   +L+ FR+    H A+V+ E+G V G+VT+ 
Sbjct: 271 AACAEGAD-VTLKNFMRQPVFIPETARALDLLEAFRTTPHVHFAMVVGEYGEVQGIVTLN 329

Query: 183 DILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE---EVDTI 239
           D+LE IVG+I    DE D+ +  + +  +W +  +  I+D  +  G    DE   + +T+
Sbjct: 330 DVLEAIVGDIPS-PDEADEPEAVRRADGSWLLDGMMHIDDMADVTGLRLPDEKHGDFETL 388

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
            GL++Q  G LPA G+T+ +    F++   D RRI +V +         
Sbjct: 389 AGLLLQHLGKLPAIGDTLRLGPLHFEIVDMDGRRIDRVLLSTAATVKDE 437


>UniRef50_UPI0001C36BB6 hypothetical protein ChatD1_07246 n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C36BB6
          Length = 351

 Score =  312 bits (802), Expect = 6e-84,   Method: Composition-based stats.
 Identities = 77/276 (27%), Positives = 149/276 (53%), Gaps = 12/276 (4%)

Query: 18  FFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           F  L+   +    E    +++++++ +  +  +++    +M+  + ++ D+   DIM  R
Sbjct: 51  FLKLIGIDMMSDNENVTEEDIMSMVNEGHEQGVLEAREAEMITNIFELDDKDAGDIMTHR 110

Query: 77  SQMITLKRNQTLDECLDVIIESAH-SRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF-- 133
             ++ L  + TL E ++ I++  + SR+PV  +D D I GIL  KD L    + +     
Sbjct: 111 KNLVALDGSMTLREAVNFILKEGYNSRYPVYEKDIDDITGILHMKDALIAAENGSNGMVP 170

Query: 134 --SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +D +LR+A  +PE++ +D + KE +SQ+ HM IV+DE+G  +G+VT+EDILE IVG 
Sbjct: 171 ICEIDGLLREAHFIPETRNIDSLFKEMQSQKIHMVIVVDEYGQTAGIVTMEDILEEIVGS 230

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFG 248
           I DEYD +++    Q    ++ +  +A +++  +     F +++    DTI G ++    
Sbjct: 231 IMDEYDVDEE-FIAQAEDGSYIISGMAPLDEVAKTLDIEFEEDDYDSYDTINGFLISRLD 289

Query: 249 HLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIP 282
            +P  GE   ++  GY FK+   +++ I  + V+  
Sbjct: 290 RIPQEGEQTEVEYQGYGFKILQVENKMIHTIRVQKL 325


>UniRef50_D0KZZ4 CBS domain containing protein n=1 Tax=Halothiobacillus neapolitanus
           c2 RepID=D0KZZ4_HALNC
          Length = 299

 Score =  312 bits (801), Expect = 8e-84,   Method: Composition-based stats.
 Identities = 129/296 (43%), Positives = 185/296 (62%), Gaps = 8/296 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M +D   SS + S++ G+F+ L  Q    + K+  ++L + + + +  +I   T  +++ 
Sbjct: 1   MDED---SSPSRSDEPGWFARLRQQWCISQVKSCSDILTVAKAAAEKQIIPHSTASLIDS 57

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V++  D RVRD+MIPR QM  +    TL + L  I E+ HSR+PVI E++D I GIL+ K
Sbjct: 58  VLEFHDSRVRDVMIPRGQMDVINITSTLPQILSEIAETGHSRYPVILENRDEITGILLVK 117

Query: 121 DLLPFMR-----SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGV 175
           +LL F        D   F++   +R A+ VPESKR+D +L EFR  R HMAIV+DEFGGV
Sbjct: 118 ELLHFYAGTPSEEDIAGFTLKNHIRSALYVPESKRLDVLLAEFRLTRTHMAIVLDEFGGV 177

Query: 176 SGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE 235
           +GLVTIED+LE IVG+I+DEYD  + +  R+ S + +TVRAL  I++FN  FGT FSD+E
Sbjct: 178 AGLVTIEDVLEEIVGDIDDEYDTAEPVHIREQSANRFTVRALTPIDEFNAHFGTDFSDDE 237

Query: 236 VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
            DTIGG +    GHLP RGE + + GY+FK+  AD RR+  + V +   S      
Sbjct: 238 YDTIGGFITHELGHLPRRGEVVCVGGYEFKILGADKRRLHLLLVTVMTPSQIENES 293


>UniRef50_A1AQM4 CBS domain containing protein n=9 Tax=Desulfuromonadales
           RepID=A1AQM4_PELPD
          Length = 296

 Score =  312 bits (801), Expect = 9e-84,   Method: Composition-based stats.
 Identities = 84/282 (29%), Positives = 151/282 (53%), Gaps = 1/282 (0%)

Query: 9   SDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
            +  +   G F L    +   +     E+  LI+ S    +++E+  +M+  +  +    
Sbjct: 16  EEGSTITSGIFKLFERFVHGRKKMTAYEIQDLIKASEDEGVVNEEESEMIRSIFSLRSTV 75

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS 128
           VR++M+PR  M  +  + T+ E L+ I+   HSR PV     D++ G+L AKD+L +   
Sbjct: 76  VREVMVPRIDMACISVDATVREILETILACGHSRIPVFENSVDNVIGLLYAKDMLKYWGL 135

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
             +   +  ++R    +PE+K ++++L+EF+++  H+AIVIDE+GG SGL+TIED+LE I
Sbjct: 136 SEDLIRVRSIMRPPYFIPETKNLEQLLQEFKNKHVHLAIVIDEYGGTSGLITIEDLLEQI 195

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VG+I+DE+D E+   F      + T  A   IE+  + F      ++ DT+GGL+    G
Sbjct: 196 VGDIQDEHDREE-ALFTTNDDGSLTADARLPIEELEQLFDMEIEHDKFDTVGGLIFHLTG 254

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
            + A G+T++ +     V  +D R+I +V +   ++      
Sbjct: 255 KISAPGDTVENEQLVIAVLDSDERKIKRVCITRKNNMETDNE 296


>UniRef50_C5PXG9 TlyC family hemolysin n=5 Tax=Sphingobacteriales RepID=C5PXG9_9SPHI
          Length = 437

 Score =  312 bits (801), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 79/256 (30%), Positives = 149/256 (58%), Gaps = 3/256 (1%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           L  L+    ++  +D    ++++ V D  ++ V++IM+PR++++ + ++ T DE ++ + 
Sbjct: 184 LQYLLDKGKESGALDFSEHELIKNVFDFNERIVKNIMVPRTKIVAIDKDATADEFINTVT 243

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLK 156
           E  +SR P+  ++ D I GI+  KD+LP +    E   +  ++R+   +PE+K+++ ++ 
Sbjct: 244 EEGYSRIPIYDDNIDQIVGIVHTKDILPIIVKGKEVV-LKNIMRKPYFIPETKKINDLMA 302

Query: 157 EFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRA 216
           EF+ +R  +AIV+DEFGG +G+VT+EDI+E +VGEI+DEYDEE  +   ++S   + + A
Sbjct: 303 EFQLKRIQIAIVLDEFGGTAGMVTLEDIVEELVGEIQDEYDEETPV-VERISETEYMIDA 361

Query: 217 LASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRII 275
            AS+ D NE       +  + DT+ GLV   F  +P  GE  ++ GY F +     + I 
Sbjct: 362 GASVHDVNEYLPLELPESSDYDTMAGLVSDLFDKIPEVGEYKELYGYTFTIMKKTQQNIE 421

Query: 276 QVHVKIPDDSPQPKLD 291
            V +++ +       +
Sbjct: 422 FVKLELIETPHDEDEE 437


>UniRef50_C3WJU6 Magnesium and cobalt efflux protein corC n=15 Tax=Fusobacterium
           RepID=C3WJU6_9FUSO
          Length = 427

 Score =  312 bits (800), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 88/272 (32%), Positives = 158/272 (58%), Gaps = 7/272 (2%)

Query: 18  FFSLLLSQLFHGE------PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           F S  + ++              +++++ +       +I+ED ++M+  ++ + +   ++
Sbjct: 148 FISRFVGRILGVNMESPQLLITEEDIISYVNVGNAEGIIEEDEKEMIHSIVTLGETSAKE 207

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M PR+ M +L+  +T++E  D I E+  SR PV  E  D+I GIL  KDL+  ++++  
Sbjct: 208 VMTPRTSMFSLEGEKTINEIWDEITENGFSRIPVYEETIDNIIGILYVKDLMEHVKNNEL 267

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              + + +R A  VPE+K +  +LKEFR+ + H+A+V+DE+GGV GLVTIED++E IVGE
Sbjct: 268 DIPIKQFVRSAYFVPETKSIIEILKEFRTLKVHIAMVLDEYGGVVGLVTIEDLIEEIVGE 327

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHL 250
           I DEYD+E+D  F++++ + + V A+  IE  N+         E+ +++GGL++   G +
Sbjct: 328 IRDEYDDEEDSFFKKIADNEYEVDAMTDIETINKELELELPISEDYESLGGLIVTTTGKI 387

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
              G+ + ID    KV   D  R+ +V +KI 
Sbjct: 388 CEVGDEVQIDNIYLKVLEVDKMRVSKVFIKIL 419


>UniRef50_B7GEW2 Hemolysin related protein containing CBS domains n=8
           Tax=Bacillaceae RepID=B7GEW2_ANOFW
          Length = 421

 Score =  312 bits (800), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 86/276 (31%), Positives = 145/276 (52%), Gaps = 2/276 (0%)

Query: 9   SDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
           +  +   K   S L+ Q         +E+  ++  S +  +ID   ++++   +D  D  
Sbjct: 143 TALLVMLKKVVSKLVGQRADVPSVTEEEIKVMVNLSEEEGVIDNKEKELVHRSLDFNDIL 202

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS 128
           V +I  PR  M+ ++ NQ ++E  D+ +   +SR PV   D D++ GIL   D    +  
Sbjct: 203 VGEIFTPRIDMVAVEVNQPVEEIRDIFLRERYSRVPVYEGDIDNVIGILSESDFFSQLVQ 262

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
             E  ++ ++LR  + V ES R+  +L E +  + HMAIVIDEFGG SGL+T+EDILE I
Sbjct: 263 GKE-VNVRELLRTPLFVVESMRISTLLPELQKSKVHMAIVIDEFGGTSGLITLEDILEQI 321

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VGEI DE+DE     F++++ + +   A   +++F    G    +    T+GG V + F 
Sbjct: 322 VGEIWDEHDEAVKT-FQKINDYEYEFNAELPLDEFCHILGIDELESSSHTLGGWVFEMFE 380

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
            +P  GE+ + +     V   ++RRI +V V+I + 
Sbjct: 381 RIPTVGESFEYETLTVTVRQVENRRIRKVLVRIREP 416


>UniRef50_D2RIW5 CBS domain containing protein n=2 Tax=Acidaminococcus
           RepID=D2RIW5_ACIFE
          Length = 284

 Score =  311 bits (798), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 81/262 (30%), Positives = 146/262 (55%), Gaps = 2/262 (0%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   + D++  ++  S +   ID     +++ V D AD+  R++M+PR  M+ L  +  +
Sbjct: 21  GTSHSEDDIRKMVSASEKGGSIDPVESRLIDNVFDFADRVAREVMVPRQDMVCLFVDDPI 80

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
           +E + VI ES H+R+P+  ED+DHI G++  ++ +         F +  ++R+  VVPES
Sbjct: 81  EENMKVIRESGHTRYPLCEEDRDHILGMVHIREFMNADYKQP-GFDLRSIMREIDVVPES 139

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             + ++L+  + +   MA V DE+GG +GLVT+ED+LE IVG+I+DE+D  D  +  ++ 
Sbjct: 140 MSIAKILQLMQHKHVQMAAVADEYGGTAGLVTMEDLLEEIVGDIQDEHDT-DMPEINKMP 198

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
             ++    L  +++ +E  G  F D E DTIGG V    G  P  G++++ +G +F+V  
Sbjct: 199 DGSYVFDGLVLLDEVSEIMGIQFDDPEEDTIGGYVFGLIGRQPVVGDSVEENGCKFEVLD 258

Query: 269 ADSRRIIQVHVKIPDDSPQPKL 290
           +   R+++V V       +   
Sbjct: 259 STGFRVLRVRVIPLKKEKKEAA 280


>UniRef50_B7RC07 CBS domain integral membrane protein n=5 Tax=Thermotogaceae
           RepID=B7RC07_9THEM
          Length = 455

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 79/277 (28%), Positives = 152/277 (54%), Gaps = 5/277 (1%)

Query: 15  KKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
             G  SL   +    +     ++++++++  G+  +I+E+   +++   ++    V++IM
Sbjct: 158 ADGIISLRDGKKVSEDLFITEEDIVSIVQVGGEMGVIEEEEERIIKRAFEMKQIAVKEIM 217

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR----SD 129
            PR  ++ ++ NQT+ + ++++ +  +SR PV  E  D+I GI  AKD+L  +      +
Sbjct: 218 TPRVDIVAIEENQTVKDLIELVEDEGYSRIPVYKETIDNIVGICYAKDVLSILAAKDCEE 277

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            +A  +  ++R+A+ VPE+  +D +LK  ++++ H+AIV+DE+GG +G+VT+EDI+E + 
Sbjct: 278 VKAMKVKDIMREALYVPETMNIDELLKILKAKKIHIAIVVDEYGGTAGIVTLEDIIEELF 337

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G I DEYD ++    R++   T+ V     I D        F + E +TI G +++ F  
Sbjct: 338 GNIMDEYDYDEISGIRKIDERTFVVDGTTPINDIEMELRVQFPETEYETIAGYLLEHFKR 397

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
           +P  GE   I    FK+      RI +V +KI +   
Sbjct: 398 IPNVGEEAVIGNLYFKILAVGKNRIEKVMIKILEGEE 434


>UniRef50_A9B0K1 Putative uncharacterized protein n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9B0K1_HERA2
          Length = 427

 Score =  311 bits (797), Expect = 3e-83,   Method: Composition-based stats.
 Identities = 84/256 (32%), Positives = 148/256 (57%), Gaps = 1/256 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +EL  ++    +  +I+ + RDM+EG+ + +D  VR++M+PR  ++ L    +++E 
Sbjct: 162 VTEEELKLMVNVGEEEGVIEAEERDMIEGIFEFSDTAVREVMVPRIDIVGLAATASMEEA 221

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           L++ I + HSR P+  E  DH+ G+L AKDL P +R       +  ++RQ+  VP+S +V
Sbjct: 222 LNLFISAGHSRLPIYDESIDHVLGVLYAKDLFPLLRDGLRDAPLRSLVRQSYFVPDSIKV 281

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D +++  +S++ HMAI++DE+G  +GLVTIED+LE IVGEI+DE+D E+    +Q+  H 
Sbjct: 282 DDLMRALQSRKVHMAIIVDEYGSTAGLVTIEDLLEEIVGEIQDEFDSEEAP-IQQVGPHE 340

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           W      SI+  N+A      +++VD++GG V+   G +P  G+ I       +V     
Sbjct: 341 WLFDGRVSIDAVNDATELTLINDDVDSLGGFVLSMLGSMPKVGDVIQAGDTTIEVVTIQG 400

Query: 272 RRIIQVHVKIPDDSPQ 287
            R  ++ + +     +
Sbjct: 401 LRPQRLRLSLAHAEHE 416


>UniRef50_D1AFV9 Putative uncharacterized protein n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1AFV9_SEBTE
          Length = 428

 Score =  311 bits (797), Expect = 3e-83,   Method: Composition-based stats.
 Identities = 79/271 (29%), Positives = 161/271 (59%), Gaps = 4/271 (1%)

Query: 14  NKKGFFSLLLSQL--FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +      +   +    H E    DE++ L+ ++ ++ L++++   +++ V +++++ V  
Sbjct: 160 STNFILRIFGIKNISTHEEIHTNDEIMLLLTENYKHGLLNKEELTLVDNVFELSEKNVMS 219

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +MIPR+ M  +     L++ +D +++  ++R+PV  E+KD+I G +  +DL   +  + E
Sbjct: 220 VMIPRTDMQCIYMGDNLEKIMDFVLDGKYTRYPVCRENKDNIIGFVHIRDLCKQVILNTE 279

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              ++ ++R+ + VP++  V+ + K F+     +AIVIDE+GG +GLVT+EDILE +VGE
Sbjct: 280 N-DIEDIMREIIFVPDTMSVNALFKRFQEDHSQIAIVIDEYGGTAGLVTLEDILEELVGE 338

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I+DE+D  D  + +++S   ++V    +I+  N+    +   + V+TIGGL    +G LP
Sbjct: 339 IQDEFDINDVSEIKKISDTVYSVDGKVTIDRINKLLNINIETK-VETIGGLFSLEYGSLP 397

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
             GE I  DGY+F +  ++++R+++V ++  
Sbjct: 398 EAGEKIIHDGYEFTIIKSNNKRVLRVKIEKI 428


>UniRef50_D1C4W4 Putative uncharacterized protein n=1 Tax=Sphaerobacter thermophilus
           DSM 20745 RepID=D1C4W4_SPHTD
          Length = 445

 Score =  311 bits (797), Expect = 3e-83,   Method: Composition-based stats.
 Identities = 86/279 (30%), Positives = 150/279 (53%), Gaps = 5/279 (1%)

Query: 18  FFSLLLSQLFHGEPK---NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           +        +  E       +EL  L+  S +   ++   ++M+  ++  AD     +M+
Sbjct: 168 WLLRPFGLRYQSESHLVYTVEELEMLVEASARGGQLETSEQEMIHRLLTFADLDAGQVMV 227

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAF 133
           PR++MI +  + TL E ++VI     SR+PV  +  D I GI+ +KDL P + +   + F
Sbjct: 228 PRTEMIAVPVDITLPELIEVIARERRSRYPVYDQTLDDIVGIVHSKDLFPILAAGKTDGF 287

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           S+ ++ R+A+ VP+S  +D++L   + +R H+AIVIDE+GG +GL+T+ED++E IVGE++
Sbjct: 288 SIREITREAMTVPDSLPIDQVLALMKQRRTHIAIVIDEYGGTAGLITMEDLVERIVGELQ 347

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DE++  +  +   L   +  +  L  IE+ NE FG    D   DTIGG V    G  P  
Sbjct: 348 DEFERPEQ-EVEVLPDGSVRINGLMLIEEVNERFGLDIHDPNFDTIGGYVFGQLGRKPEV 406

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           G+T+ +    F+V + D  RI ++ +       + +  E
Sbjct: 407 GDTVQVGDVTFRVDVLDGLRIARLCLIRDHVPSEEQAGE 445


>UniRef50_B9Z7Q6 Putative uncharacterized protein n=1 Tax=Lutiella nitroferrum 2002
           RepID=B9Z7Q6_9NEIS
          Length = 440

 Score =  310 bits (795), Expect = 4e-83,   Method: Composition-based stats.
 Identities = 71/282 (25%), Positives = 134/282 (47%), Gaps = 7/282 (2%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
                 L+ ++         +E+  L+       + D   ++++E +  + D++V  IM 
Sbjct: 157 TDAILRLMGAKKSKEPSITEEEIKVLMEQGADEGVFDRAEQELVENIFRLDDRKVASIMT 216

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR  +I+L           ++    +SR+PV     D + GI+ AK LL  + S   +  
Sbjct: 217 PRKDIISLDIEDDHTSNCQLMQSHPYSRYPVCKGGMDQLIGIVDAKHLLDRLLSGG-SVD 275

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
               +   + VP +  + ++L++F+  R HMA+V+DE+G + GLVT+ D+LE IVG +  
Sbjct: 276 FTAGMHPPLYVPATVSLMQLLEQFKRARIHMALVVDEYGELEGLVTLHDVLESIVGGLP- 334

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH--FSDEE---VDTIGGLVMQAFGH 249
              +ED+    Q   H+W V  + + ++  E F        E+   + T+GG+VM   G 
Sbjct: 335 AGPQEDEQLIIQRDEHSWLVDGMVAPDELREHFAIDSLLPGEDTGNIHTLGGVVMFQLGR 394

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           +P   +  + +G+ F+V   D  R+ +V V     +  P+ +
Sbjct: 395 VPVAADRFEWNGFAFEVVDMDKTRVDKVMVSRLQAASAPEEE 436


>UniRef50_P74409 UPF0053 protein sll0260 n=28 Tax=cellular organisms
           RepID=Y260_SYNY3
          Length = 448

 Score =  309 bits (794), Expect = 5e-83,   Method: Composition-based stats.
 Identities = 74/274 (27%), Positives = 135/274 (49%), Gaps = 6/274 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      L         P   +E+  +I    Q  +IDE  ++M+E V  + D+ V+ +M
Sbjct: 163 STDAVLRLFGITSKEASPITEEEIRVMIEQGAQAGMIDEAEQEMVERVFRLGDRPVKTLM 222

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR+ +  L      +E    I+++ +SRFPV  +  D   G +  KD+L    S  +  
Sbjct: 223 TPRTAIAWLDVESDWEENQQEILDTPYSRFPVGRDSLDECLGFVRVKDILNSQWSGQK-I 281

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           +++++++  + V E+ R   +L+ FR+   H+A++ DE+GG+ GLVT+ D++E IVG I 
Sbjct: 282 NLEEIVQPPLFVAENTRSLHVLEMFRASGTHLALITDEYGGIEGLVTLNDLIEAIVGSIP 341

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH----FSDEEVDTIGGLVMQAFGH 249
           ++ DE  +    Q    ++ +  L  I++F E F         +    T+GG V+++ G 
Sbjct: 342 ND-DEIQEPQIIQREDGSYLLDGLLPIDEFKEIFDIETLSNEEEGHYHTLGGFVIESLGK 400

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           +P  G+    D  + +V   D  RI +V V    
Sbjct: 401 IPQSGDYFVSDTLRVEVVDMDGIRIDKVLVNQLP 434


>UniRef50_A9KLG3 Putative uncharacterized protein n=1 Tax=Clostridium
           phytofermentans ISDg RepID=A9KLG3_CLOPH
          Length = 487

 Score =  309 bits (794), Expect = 6e-83,   Method: Composition-based stats.
 Identities = 77/285 (27%), Positives = 158/285 (55%), Gaps = 8/285 (2%)

Query: 14  NKKGFFSLLLSQLFH-GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           N  G   L   +     +    +E+++++ +  +  +++ +  +M+  +++  ++  +DI
Sbjct: 164 NTNGILRLFGIRPSDLEDNVTEEEIMSMVNEGHEQGVLEAEEAEMISNIIEFNEKAAKDI 223

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL-LPFMRSDAE 131
           M  R +MI +     +++ L  +++  +SRFP+   D D+I G+L  KD+ L F+    +
Sbjct: 224 MTHRKKMIAINSALCIEDALRFMLDENYSRFPLYDGDIDNIVGLLHLKDVMLYFLDPRLK 283

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              + KV R+   +P+++ +D +  + ++++ HMAI IDE+G  +G+V +EDILE IVG+
Sbjct: 284 VEPLSKVAREPYFIPDTQSIDVLFHDMQTKKIHMAIAIDEYGQTAGIVAMEDILEEIVGD 343

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFG 248
           I+DEYD+E+++ + +L   ++ +   AS+ED  +     F++E+    DT+ GL++    
Sbjct: 344 IQDEYDDEEEL-YTRLEDDSYLLSGEASLEDLEDILSLPFAEEDIKNYDTLNGLIVSLLD 402

Query: 249 HLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           H+P   E  TI   GY++++    +R I  V V+   +      D
Sbjct: 403 HIPGDDERATIRYCGYEYELMEIQNRMITSVRVRKIPEEELKASD 447


>UniRef50_B7J5B5 Magnesium and cobalt efflux protein, putative n=2
           Tax=Acidithiobacillus ferrooxidans RepID=B7J5B5_ACIF2
          Length = 291

 Score =  309 bits (793), Expect = 7e-83,   Method: Composition-based stats.
 Identities = 120/290 (41%), Positives = 180/290 (62%), Gaps = 5/290 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S         +G++    +Q   G  +++D LL LIR++G+  +ID +T  M++G
Sbjct: 1   MSEDRSSQERP----RGWWERF-TQSLRGNVEDQDTLLELIREAGERQIIDAETARMVDG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           +  + +  VRD+MIPR+QM  ++ +  L E +  + E  HSRFPV+  D+D + GIL+AK
Sbjct: 56  IFRMGELTVRDVMIPRAQMEVIELDMPLAEIIARVSEVGHSRFPVVGHDRDDVRGILLAK 115

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL   R D  A  +  +LR A  +PESK +D +L EFR+ R+HMA+V+DE+GGV+GL+T
Sbjct: 116 DLLRGCRGDVPALRLTDLLRPATFIPESKHLDHLLYEFRTGRHHMAVVVDEYGGVAGLIT 175

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IED+LE+IVGEIEDEYD ++D+         + V AL  +E+FN  F TH  D   DT+G
Sbjct: 176 IEDVLEIIVGEIEDEYDIDEDVMIAPREDGDFLVNALIPLEEFNAHFVTHLEDGHADTLG 235

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           G V  A GH+P  GE ++    + +V  AD +R+  + V  P  +P P+ 
Sbjct: 236 GWVAAALGHVPRTGEVVEEGDLRLEVLRADRKRVQILRVTPPRGAPLPET 285


>UniRef50_C4Z1L1 Putative hemolysin n=2 Tax=Bacteria RepID=C4Z1L1_EUBE2
          Length = 293

 Score =  309 bits (792), Expect = 8e-83,   Method: Composition-based stats.
 Identities = 80/292 (27%), Positives = 155/292 (53%), Gaps = 11/292 (3%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M+D   H +D    K         +    E    +E++ ++ +S +  +++E+  +M+  
Sbjct: 1   MNDG--HPADGKEKKFSSLFKRFGRGKRDEDVT-EEIMDMVNESHEQGVLEENEAEMIGN 57

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           + +  +++  D+M  R+ ++ L  + T+ E  D ++E  +SR+PV   D D+I G+L  +
Sbjct: 58  IFEFGEKQASDVMTHRNNIVALDNDITVKEAFDRVMEENYSRYPVYDGDIDNITGVLHIR 117

Query: 121 DLLPFMRSDAEAFSM-----DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGV 175
           DLL     ++           ++L Q   +PE++ +  + ++ +S + HMAIV+DE+G  
Sbjct: 118 DLLKIYVEESNQSRKLGEVGKEILFQPYCIPETRNISPLFRQMQSDKIHMAIVVDEYGQT 177

Query: 176 SGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE 235
           +G++T+EDILE IVG I DEYD+E++      +  ++ +   A +ED     G  F  E+
Sbjct: 178 AGIITMEDILEEIVGNILDEYDDEEE-QIVTDADGSYIIEGQADLEDVEARLGIEFECED 236

Query: 236 VDTIGGLVMQAFGHLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           +DT+ G ++   G +P  GE   ++ +GY FK     +R I++V V+  +  
Sbjct: 237 IDTLSGFMIYKLGKIPDDGESFEVEYNGYIFKTLEVRNRMILKVKVEKENRE 288


>UniRef50_C9L5N7 Hemolysin-related protein n=1 Tax=Blautia hansenii DSM 20583
           RepID=C9L5N7_RUMHA
          Length = 463

 Score =  309 bits (792), Expect = 8e-83,   Method: Composition-based stats.
 Identities = 81/284 (28%), Positives = 161/284 (56%), Gaps = 13/284 (4%)

Query: 19  FSLLLSQLFHGEPK------NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
            S ++ +LF  +P         +E+++++ D+ +  +I+E+  +M++ +M+ ++   +DI
Sbjct: 171 LSNVVVRLFGVDPHKQEDDVTEEEIISMVDDAHEQGVIEENEAEMIQNIMEFSETEAQDI 230

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR----S 128
           M  R  +  ++ N  L + L  ++++++SR+PV  ED D+I GIL  KD++  +      
Sbjct: 231 MTHRKNLHAIEENTLLKDALSYMLDNSNSRYPVYREDIDNIIGILHLKDVMRQITLPECE 290

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           +    S+  ++R+AV VPE++ ++ + K  ++++ H+ +V+DE+G  SG+VT+EDILE I
Sbjct: 291 NLPIGSIPNLVREAVYVPETRSINDLFKRMQAKKIHLVVVVDEYGQTSGIVTMEDILEEI 350

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VG I DEYDE+++   +  +  +  +  L  +E  ++   + F +EE DT+ G +    G
Sbjct: 351 VGNILDEYDEDEN-FIQLQNDQSLVMNGLTPLEQVDDVLNSDFDEEEFDTLNGYLTSLLG 409

Query: 249 HLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           H+P   E   I   GY F +   ++  I +V V+   D  + + 
Sbjct: 410 HVPNMAEDKEIKAKGYLFTILAVENNTIQKVRVEKLPDEEKGEE 453


>UniRef50_B8JAD7 Putative uncharacterized protein n=4 Tax=Anaeromyxobacter
           RepID=B8JAD7_ANAD2
          Length = 464

 Score =  309 bits (792), Expect = 9e-83,   Method: Composition-based stats.
 Identities = 86/303 (28%), Positives = 148/303 (48%), Gaps = 30/303 (9%)

Query: 9   SDTISNKKGFFS-LLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           S  ++   G+    L            +E+  LI    +  ++DE   ++L  V++ AD+
Sbjct: 148 SAAVTRLTGWVVGRLGGGRAPTPAVTSEEIEYLIEMGTREGVLDEVKEELLNSVLEFADR 207

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
             +++MIPR++M+ + R    DE + ++ E+ +SR PV     D++ GIL+ +D++  +R
Sbjct: 208 VAKEVMIPRTRMVAVDRAVEPDELVRIVTENPYSRMPVYEGSIDNVVGILLVRDIIQELR 267

Query: 128 SDA-EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
                  ++D+ L+ A  VPE  ++ R+LKE + +R H+A+V+DEFGG SGLVT+ED++E
Sbjct: 268 HGPLRRIALDRYLKPAFFVPEQMKISRLLKEMQRRRTHLAVVVDEFGGTSGLVTMEDVIE 327

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG------------------ 228
            IVGEI+DE D  +    + ++   W   A   + D                        
Sbjct: 328 EIVGEIQDEAD-VESAPVKAVAPGVWLADAAIPLHDLQSFLNEQREEPAPRPAGDDAPEP 386

Query: 229 --------THFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
                     F +  + +T+GG V    G +P  G T+  DG  F V   D RR+ +V +
Sbjct: 387 EDGEPPPEIRFPEQGDYETLGGFVTATAGRVPPVGATLAWDGLTFTVRAGDERRVTRVEI 446

Query: 280 KIP 282
              
Sbjct: 447 ARR 449


>UniRef50_C6J8N4 Putative uncharacterized protein n=1 Tax=Ruminococcus sp.
           5_1_39BFAA RepID=C6J8N4_9FIRM
          Length = 459

 Score =  309 bits (792), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 83/289 (28%), Positives = 152/289 (52%), Gaps = 15/289 (5%)

Query: 10  DTISNKKGFFSLLLSQLFHGE------PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMD 63
              +    + + L +  F  E          +E+++++ ++ +  +I E+  +M++ ++ 
Sbjct: 169 KPFTVSVTWIARLAAVPFGVEINRTEKSVTEEEIISIVDEAHEQGVIQENEAEMIQNIIS 228

Query: 64  IADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL 123
             +    DIM  R  ++       L   +D ++E  +SR+PV  E+ D+I+GI+  KD L
Sbjct: 229 FNETEAHDIMTHRKNVVAFDEEILLKNMIDTMLEEGNSRYPVYEENIDNIKGIVHYKDAL 288

Query: 124 PFMRSDAEA-----FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
            FM  +  A       +  ++RQA ++PE++ +  +    ++++ HMAIV+DE+G  +G+
Sbjct: 289 KFMTQNPWAKFKPLKELPGIIRQASLIPETRGIGDLFHTMQARKIHMAIVVDEYGQTAGI 348

Query: 179 VTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDT 238
           VT+EDILE IVG+I DEYD ED+I  R    ++  +  LA +ED  E     F D E +T
Sbjct: 349 VTMEDILEEIVGDILDEYD-EDEITIRAQKDNSLIIDGLAYLEDVEEELDADFGDTEFET 407

Query: 239 IGGLVMQAFGHLPA---RGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           + G +    GH+PA      +I   GY F +    ++ I +V V+  ++
Sbjct: 408 LNGYLTNILGHIPADKDVNTSIKAIGYCFTILSIGNKTIGKVKVERDNN 456


>UniRef50_Q2FTJ8 Putative uncharacterized protein n=4 Tax=Methanomicrobiales
           RepID=Q2FTJ8_METHJ
          Length = 429

 Score =  308 bits (791), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 82/269 (30%), Positives = 151/269 (56%), Gaps = 5/269 (1%)

Query: 27  FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQ 86
           F       +E+   I    +   I++D ++ML  V + +D RVR++M PR  ++ L+   
Sbjct: 159 FAHHMITEEEIKEWIDVGQEEGTIEKDEQEMLHSVFEFSDTRVREVMTPRIDVVMLEDTS 218

Query: 87  TLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVP 146
           + DE L++   +  SR P+   + D I+GIL  KD +  +    E+  + ++L + + VP
Sbjct: 219 SSDEALEIFKNTGFSRLPIWHGNIDTIKGILNVKDAIFSVLETHESIPIVELLSEPLFVP 278

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           E+K +D +L+E R+++ HMAIV+DE+G   G+VT+EDILE +VG+I DE+D E+  +  +
Sbjct: 279 ETKNIDDLLRELRAKKTHMAIVLDEYGSFVGIVTVEDILEELVGDILDEFDTEEH-ELVR 337

Query: 207 LSRHTWTVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAFGHLPARGET--IDIDGYQ 263
           ++   ++V A   +ED N+    H    E  +TI GLV++  G++P  G+   +  +G +
Sbjct: 338 VAEDVYSVDARMWVEDLNKHLDLHLPTSETYETIAGLVIERLGNIPRIGDVCDLTEEGVR 397

Query: 264 FKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
             +     +RI ++ +      P+P  ++
Sbjct: 398 LVIIQMTGKRINRLKLIRI-HPPEPSDEQ 425


>UniRef50_B3QS78 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B3QS78_CHLT3
          Length = 460

 Score =  308 bits (791), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 79/281 (28%), Positives = 140/281 (49%), Gaps = 9/281 (3%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      L+  +  +      DE+  LI+   Q  + +    DM+  +  ++D+RV  IM
Sbjct: 180 SANLVLHLIGIKNSNEPDVTEDEIKMLIKQGTQLGVFEAVEHDMVLRIFRLSDRRVSAIM 239

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL----LPFMRSD 129
            PR+ +  +    + DE  + +++  HSRF V   D D+++GI+  KD+         ++
Sbjct: 240 TPRTDIEWIDLEDSEDEIRNQLMQKTHSRFVVAHGDLDNVDGIIRVKDVAMTGFSTPIAN 299

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            +   +   LR+ + VPE+  V  +++ F+ +R  MA++IDE G V G+VT+ DILE IV
Sbjct: 300 LKVL-LKSRLRKPLYVPETLPVFNLMENFKKKREQMALIIDEHGSVQGIVTLNDILESIV 358

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQA 246
           G++  E DE ++    +    +W +  +  I++F E F    S EE     T+GG VM  
Sbjct: 359 GDLPFE-DEPEEQSILEREDGSWLIDGMLPIDEFWEFFNIKSSQEEEWGYQTLGGFVMTK 417

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            G +P   +T D    +F+V   D +R+ +V V    +   
Sbjct: 418 LGRIPVTSDTFDAHQMRFEVVDMDGKRVDKVLVSRLPNGES 458


>UniRef50_A3ZXV1 Hemolysin protein n=1 Tax=Blastopirellula marina DSM 3645
           RepID=A3ZXV1_9PLAN
          Length = 430

 Score =  308 bits (790), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 88/256 (34%), Positives = 148/256 (57%), Gaps = 2/256 (0%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           +  ++ +  +  L++ED R+M+E V+++ D  V D+M  RS++  L    + ++ +  + 
Sbjct: 175 IRTIVTEGLREGLLEEDAREMIESVIELGDIDVADVMTSRSEVDALPIETSWEDVVKFVH 234

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAFSMDKVLRQAVVVPESKRVDRML 155
           E+  +R P   E  D I G+L  KD+L  +   A +  S+  + R+A +VP+S  +D +L
Sbjct: 235 ETGRTRIPAYHEGLDQIVGVLYVKDMLSELVKPAADRKSLRDLARKAAMVPKSMPIDELL 294

Query: 156 KEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVR 215
           K+F  +R HMAIVIDE+  V+GL+TIEDILE IVGEI DE+D+ ++ +  ++SR    V+
Sbjct: 295 KQFLRERNHMAIVIDEYHAVAGLITIEDILEEIVGEIVDEHDQNEEEEIVRISRDQAEVQ 354

Query: 216 ALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRI 274
             A I+D NE  G      ++ DT+ G+V+     +P  G+ I +D  +  V  AD RRI
Sbjct: 355 GRAHIDDVNEELGLDLPVGDDYDTLAGMVISRLQKIPKTGDRIRVDDVEIVVIAADRRRI 414

Query: 275 IQVHVKIPDDSPQPKL 290
            ++ +   D +  P  
Sbjct: 415 QKLQLTKLDPAESPST 430


>UniRef50_B2V0W8 Putative membrane CBS domain protein n=14 Tax=Clostridiales
           RepID=B2V0W8_CLOBA
          Length = 417

 Score =  307 bits (789), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 85/268 (31%), Positives = 143/268 (53%), Gaps = 3/268 (1%)

Query: 13  SNKKGFFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +    F  +L       EP    +EL  ++  S +  +++   ++M+  V D AD +V+D
Sbjct: 147 AISSFFIKILGGDPKASEPFITEEELKTMVGVSEEEGVLENVEKEMIFNVFDFADLQVKD 206

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M+ R  +  L    T D+ L +I E   SR P+ ++  D I GIL  KDLL  + +  E
Sbjct: 207 VMVQRVDVSALDSEATYDDVLKLIKEEQFSRIPIYNQTIDDIIGILNVKDLL-MLENPRE 265

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            F M+K +R+     E K++  + KE + +R H+A+V+DE+GG  G++TIED++E IVG+
Sbjct: 266 NFKMEKYIREPYYTFEFKKIVELFKEMKKERNHIAVVLDEYGGTVGIITIEDLIEEIVGD 325

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           IEDEYD+  +     +  + + V     + D  +  G     +E D++GGL++   G +P
Sbjct: 326 IEDEYDDA-NTSIEVIKDNEYIVDGSVRLHDIGDLIGIDMESDEFDSVGGLIIGELGRMP 384

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHV 279
              E I+ D  +F V   D  RI +V +
Sbjct: 385 EEKEEIECDSMKFIVENIDKNRIKKVRI 412


>UniRef50_A0PYY8 Integral membrane protein with CBS domains n=15 Tax=Clostridiaceae
           RepID=A0PYY8_CLONN
          Length = 422

 Score =  307 bits (787), Expect = 3e-82,   Method: Composition-based stats.
 Identities = 78/260 (30%), Positives = 140/260 (53%), Gaps = 2/260 (0%)

Query: 12  ISNKKGFFSLLLSQLFHGEPK-NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           ++       +   +   G+P    +EL  ++  S +  +++ + R M+  V +  D +V+
Sbjct: 149 VALTNKIVGIFGGKASMGKPHITEEELKTIVDVSHEEGVLEVEERKMIYNVFEFGDSQVK 208

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           D+M+PR++M ++  + T DE L+V+ +   SR PV  +  D+I GIL  K L+ F  +  
Sbjct: 209 DVMVPRTEMASVDIDSTYDEILEVLKKEQFSRIPVYKDSTDNIIGILHIKKLV-FFDNSK 267

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           E F + K + +     E K    + +E R  R  M +V+DE+GG +G+VT+ED++E IVG
Sbjct: 268 EKFDITKYMVKPYFTYEYKPTTELFEEMRKDRVAMTVVLDEYGGTAGIVTMEDMVEEIVG 327

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           +IEDEYD E + + + +    + V+    I++ NE  G     E+ D+IGG V+   G  
Sbjct: 328 DIEDEYDNEQNDEIKLIKDDEYIVKGSTKIDEVNEMLGIDIESEDFDSIGGFVIGEVGRF 387

Query: 251 PARGETIDIDGYQFKVAMAD 270
           P +GE ++ D  +  +   +
Sbjct: 388 PKKGEFVEYDDVKLIIEEIE 407


>UniRef50_B8J2R3 CBS domain containing protein n=3 Tax=Desulfovibrio
           RepID=B8J2R3_DESDA
          Length = 371

 Score =  307 bits (787), Expect = 3e-82,   Method: Composition-based stats.
 Identities = 96/273 (35%), Positives = 155/273 (56%), Gaps = 5/273 (1%)

Query: 16  KGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
              +S L     H +   ++ L   I ++     ++ D   ML G++   D +V+D MIP
Sbjct: 9   STIWSRLSRLFGHDD---QESLEKAILEARAEGEVEPDEESMLLGILRFNDLQVQDTMIP 65

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS- 134
           R+ +  +  +  + E   +I+ S HSR PV  E +D+I GIL AKDLL  M       S 
Sbjct: 66  RTDIDCVPHDMPMAEVAAIIVRSGHSRIPVYKETRDNIVGILHAKDLLRSMLDGEGKVSS 125

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +  ++R+   VPE+K +  +L+EFR+++ H+AI +DE+GG SGL+TIED+LE IVG+IED
Sbjct: 126 LAGLIREPFFVPETKSIRTLLQEFRARKQHIAIALDEYGGTSGLITIEDVLEEIVGDIED 185

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARG 254
           E+D   + D R +  + + +   A +ED  +  G     +EVDTIGG +    GH+PA G
Sbjct: 186 EHDTPREEDIRPVGDNIYELTGRALLEDLED-MGVDLDSDEVDTIGGYLSMEAGHVPAPG 244

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           E+  + G+ F V  AD + I+++ ++  D +  
Sbjct: 245 ESFTLRGWTFTVLEADRKLILRLRMEPADSAAS 277


>UniRef50_Q1DCR5 CBS/transporter associated domain protein n=2 Tax=Cystobacterineae
           RepID=Q1DCR5_MYXXD
          Length = 455

 Score =  307 bits (787), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 82/240 (34%), Positives = 140/240 (58%), Gaps = 2/240 (0%)

Query: 45  GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFP 104
              + +D+    ++  + +++D+R RD+M+PR++++T+    T DE L ++ E  HSR P
Sbjct: 189 AAKNEVDKSAPQLIRSIFELSDKRCRDVMVPRTEVVTVDVTITPDELLRLLAEENHSRIP 248

Query: 105 VISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYH 164
           V  +D DH+ G+L A+D++P +    E   +  ++R A  VP  K +  +L++ + Q+ H
Sbjct: 249 VYRDDVDHVIGVLHARDIIPLL-QHPELIVLQDIIRPAHFVPWMKPIGDLLRDMQKQKIH 307

Query: 165 MAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFN 224
           MAIV+DE+GG  G+VT+EDIL  IVG+I DE+ E ++    +L+  ++ V A   ++ F 
Sbjct: 308 MAIVVDEYGGFMGVVTLEDILREIVGDIGDEF-EVEEKQVEKLADGSFLVDAALEVDAFT 366

Query: 225 EAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           + FG    + + DT+GG +    GHLP  GE     G+QF VA  +  RI +V +     
Sbjct: 367 QTFGFPLPEGDFDTLGGFLSSMAGHLPDVGERFAYSGWQFVVASKEGPRIDRVRMSRVKS 426


>UniRef50_B6IU27 CBS domain protein n=2 Tax=Rhodospirillum RepID=B6IU27_RHOCS
          Length = 434

 Score =  307 bits (787), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 73/277 (26%), Positives = 135/277 (48%), Gaps = 4/277 (1%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           ++ +    LL            +E+ +LI +   + + + + + M+EGV+ ++D+ VR I
Sbjct: 158 ASTEAMLKLLRIPDRPDSTVTEEEVKSLIAEGTASGVFEPEEKRMIEGVLRLSDRTVRSI 217

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR  +  L  +   D     I E+ HSR+ V   D D + G++  +DLL    +    
Sbjct: 218 MTPRLDVDWLDVDADPDSLRRDIQEAGHSRYVVCRGDLDDVVGVVHIRDLLEAQFAGR-P 276

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +    R A+VV +   V R+L+ F+     +A+ +DE+G V G+ T+ D++E I G++
Sbjct: 277 LDLRAATRDALVVHDGTEVMRLLELFKKTGQQIAVAVDEYGSVEGVATLTDVMEAIAGDL 336

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAF---GTHFSDEEVDTIGGLVMQAFGH 249
            +  +E ++ D  + +  ++ +  + ++E+             D E  TI G V+   GH
Sbjct: 337 PEAGEEGEEADVVRRADGSYLIDGMLAVEEVESLLSLRSLRDEDGEYHTIAGFVLFKLGH 396

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
           +P  GE    DG++F+V   D+RRI +V V       
Sbjct: 397 IPKAGEGFSHDGWRFEVVDMDARRIDKVMVSRLTQQE 433


>UniRef50_P67130 UPF0053 protein Rv2366c/MT2435 n=36 Tax=Actinomycetales
           RepID=Y2366_MYCTU
          Length = 435

 Score =  307 bits (787), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 92/279 (32%), Positives = 151/279 (54%), Gaps = 10/279 (3%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
                +G   +  EL  ++  + Q  ++  D R M+E V ++ D   R++M+PR++MI +
Sbjct: 154 GRGFRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPAREVMVPRTEMIWI 213

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR---SDAEAFSMDKVL 139
           + ++T  + + + + S HSR PVI E+ D I G++  KDL+       +     ++ +V+
Sbjct: 214 ESDKTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYLKDLVEQTFCSTNGGRETTVARVM 273

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
           R AV VP+SK +D +L+E +  R HMA+++DE+G ++GLV+IED+LE IVGEI DEYD+ 
Sbjct: 274 RPAVFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQA 333

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETID 258
           +      L    + V A   IED  E +G  F D+ +VDT+GGL+    G +P  G  + 
Sbjct: 334 ETAPVEDLGDKRFRVSARLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVI 393

Query: 259 IDGYQFKVAMADSR----RIIQVHVKI--PDDSPQPKLD 291
             G +             RI  V +    PD +   + D
Sbjct: 394 SHGLRLHAEGGTDHRGRVRIGTVLLSPAEPDGADDEEAD 432


>UniRef50_B5JWG7 CBS domain containing protein n=3 Tax=Gammaproteobacteria
           RepID=B5JWG7_9GAMM
          Length = 298

 Score =  306 bits (786), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 133/294 (45%), Positives = 193/294 (65%), Gaps = 3/294 (1%)

Query: 1   MSDDNSHSSD--TISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDML 58
           M D+ S SS     +++  +   L       +P+N D++L ++RD+ +  L D     M+
Sbjct: 1   MKDEPSSSSRQGRSASQPNWLEKLGQAFGGNDPQNLDQILEVLRDAQERGLFDLHALAMV 60

Query: 59  EGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILM 118
           EGV ++ + RVRDIMIPRS M  L++     + L+++ ES HSRFPVI+ D+D + G+L+
Sbjct: 61  EGVFEVTEMRVRDIMIPRSHMTVLEQGADFGDVLNILTESGHSRFPVIAGDRDELVGVLL 120

Query: 119 AKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           AKD+L +     E F++D +LRQ V++PESKR+  +L EFRS R H+A+V+DE+GGVSGL
Sbjct: 121 AKDVLKY-AGRPEEFALDDILRQVVIIPESKRLITLLNEFRSSRNHLAMVVDEYGGVSGL 179

Query: 179 VTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDT 238
           VTIED+LE+IVGEI+DE+D E+D   R   +  +TV AL  IE+FN  F T  SDE+ DT
Sbjct: 180 VTIEDVLEVIVGEIDDEHDSEEDHYIRPHRKGHYTVHALTEIEEFNAFFKTTLSDEDADT 239

Query: 239 IGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           IGG VM+  GH+P RGE ++ +G  F V  ADSRRI ++ V   +   +P + E
Sbjct: 240 IGGYVMRLLGHVPKRGEQVESEGILFTVLGADSRRIYRLKVTTEESLDEPTMAE 293


>UniRef50_D1C1Y5 CBS domain containing protein n=1 Tax=Sphaerobacter thermophilus
           DSM 20745 RepID=D1C1Y5_SPHTD
          Length = 424

 Score =  306 bits (785), Expect = 7e-82,   Method: Composition-based stats.
 Identities = 95/285 (33%), Positives = 156/285 (54%), Gaps = 9/285 (3%)

Query: 12  ISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQND----LIDEDTRDMLEGVMDIADQ 67
           ++        L+ +   GE  N ++      ++ +       I+ED ++M+ GV+ + + 
Sbjct: 141 LTTVADLIIRLVRRGAPGEAGNGED----AGEAHEGGNGDLDIEEDEQEMISGVLGLEEA 196

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
            VR+IM+PR  ++   ++ ++ E +D+   + HSR PV  +  D I G++ AKDLL F+ 
Sbjct: 197 TVREIMVPRLDIVAAPQDMSISEVVDLARSAGHSRIPVYRDSIDSIVGVIYAKDLLRFVN 256

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
             A    +  +LR A  VPESK VD +L++ R  + H+AIV+DE+GG +GLVTIEDILE 
Sbjct: 257 EQATGVKLLDLLRPAYFVPESKHVDELLRDMRQAKVHIAIVVDEYGGTAGLVTIEDILEE 316

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           IVGEI+DEYD E  +   +L      V    ++++  + F T F++ E  TIGG V +  
Sbjct: 317 IVGEIQDEYDRETPL-IERLGAEEVIVDGRIAVDEIADIFETEFAEGETGTIGGFVQKRL 375

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           G +P  GE++  DG   +V   +  RI ++ V    +      +E
Sbjct: 376 GRIPKAGESLRADGLLIEVQAVEHHRIRKLRVVRVREDGTAVSEE 420


>UniRef50_Q5ZVK1 Mg2+ and Co2+ transporter CorC n=6 Tax=Legionella
           RepID=Q5ZVK1_LEGPH
          Length = 296

 Score =  306 bits (785), Expect = 7e-82,   Method: Composition-based stats.
 Identities = 122/269 (45%), Positives = 179/269 (66%), Gaps = 1/269 (0%)

Query: 10  DTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           + + +   +FS L  Q   GEP+N++EL++L+RD+    LI+ +T  M+EG +  +  RV
Sbjct: 13  NKLEDGGSWFSRL-KQFLQGEPQNQEELVSLLRDAQIRSLINSETLAMIEGAILFSKMRV 71

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           RDIM+P++QM+ + ++      + ++ ++ HSRFPV  E+ D + GIL AKDLL +   +
Sbjct: 72  RDIMLPKNQMVCINKDDDFKHIISIVTQTGHSRFPVTGENSDEVVGILHAKDLLKYQPEN 131

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            E+F +  + RQ   VPES+R+D +L EFRS R HMAIV+DE+G VSG VTIEDI+E I+
Sbjct: 132 MESFDLLDICRQVTFVPESRRLDSLLSEFRSNRNHMAIVVDEYGEVSGFVTIEDIIEQII 191

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G+IEDE+D ++D   +    H + ++A   IE+FNE     FSDE  DTIGG+V+  FG+
Sbjct: 192 GDIEDEFDIDEDAYIKTHEGHCYIIKAHTPIEEFNEQLNADFSDETYDTIGGIVLNKFGY 251

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVH 278
           LP RGE I ID ++FKV  ADSRRI  + 
Sbjct: 252 LPQRGEVIIIDDFEFKVLNADSRRIKLLE 280


>UniRef50_B5YET1 GldE n=2 Tax=Dictyoglomus RepID=B5YET1_DICT6
          Length = 377

 Score =  306 bits (784), Expect = 7e-82,   Method: Composition-based stats.
 Identities = 89/279 (31%), Positives = 148/279 (53%), Gaps = 7/279 (2%)

Query: 9   SDTISNKKGFFSLLLSQLFHG--EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           +  I      F   + +           DE L L+    +  +I+++ ++++  V++  D
Sbjct: 88  TRLILGFSNIFYKFMGKTRENISPFATVDEFLTLVNVGEKEGIIEKEEKELISNVLEFTD 147

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
             V +IM+PR  M+ +  +  L E    IIE  HSR PV     D+I GI+ AKD+L  +
Sbjct: 148 TEVHEIMVPRIDMVCVSVDSPLKEVWKKIIEEGHSRIPVYEGSIDNIVGIVHAKDVLKAL 207

Query: 127 RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
                   +  +LR  + VPE+ +++ +  E R ++ H+AIV+DE+GG +GLVT+ED+LE
Sbjct: 208 AEKDPNVKIKDILRDVIYVPENMKINELFNEMRKKKAHLAIVVDEYGGTAGLVTLEDVLE 267

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAF----GTHFSDEEVDTIGGL 242
            +VGEIEDEYD+E++  F  L  +T  V A  +I + N+      G    + E DT+GGL
Sbjct: 268 ELVGEIEDEYDKEENK-FNFLDENTLIVDAKMNIYELNDILEETWGITLPETEYDTLGGL 326

Query: 243 VMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
           ++     +P+RGE ID+      +     +RI +V +  
Sbjct: 327 ILDLLNRVPSRGEQIDLGDLIIVIESVRRQRIEKVKIIR 365


>UniRef50_Q9KTE3 Magnesium and cobalt efflux protein corC n=42 Tax=Proteobacteria
           RepID=CORC_VIBCH
          Length = 291

 Score =  305 bits (783), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 189/283 (66%), Positives = 233/283 (82%), Gaps = 2/283 (0%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M++DNS +S+  S  K FF  L SQLF GEPK+R EL+ +IRDS  NDLID DTRDMLEG
Sbjct: 1   MNEDNSQNSEGPSR-KSFFERL-SQLFQGEPKDRQELVDVIRDSEVNDLIDHDTRDMLEG 58

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           VM+IA+ RVRDIMIPRSQM+T+ R   LD  + ++ ++ HSR+PVISEDKDH+EGIL+AK
Sbjct: 59  VMEIAEMRVRDIMIPRSQMVTIDRTHNLDALVAIMTDAQHSRYPVISEDKDHVEGILLAK 118

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL ++ S+   F++ +V+R AVVVPESKRVDR+LKEFR +RYHMAIV+DEFGGVSGLVT
Sbjct: 119 DLLKYLGSNCAPFNIQEVIRPAVVVPESKRVDRLLKEFREERYHMAIVVDEFGGVSGLVT 178

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IEDILE IVG+IEDE+D+E+  D RQLS+HT++V+AL +IEDFN  FGT FSDEEVDT+G
Sbjct: 179 IEDILEEIVGDIEDEFDDEEQKDIRQLSKHTFSVKALTTIEDFNHTFGTKFSDEEVDTVG 238

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           GLVM AFGHLPARGE +DI GY FKV  ADSRR++ + V +PD
Sbjct: 239 GLVMTAFGHLPARGEVVDIAGYNFKVTAADSRRVVALQVTVPD 281


>UniRef50_D1Y8K5 Putative transporter n=1 Tax=Pyramidobacter piscolens W5455
           RepID=D1Y8K5_9BACT
          Length = 430

 Score =  305 bits (783), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 84/258 (32%), Positives = 142/258 (55%), Gaps = 1/258 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
             RDE+  L+++  ++  I+   R M++GV+   + RV +IM+PR  M  L+ N+T+   
Sbjct: 166 VTRDEIEQLVKNGEESGAIEASERRMIDGVIAFDETRVSEIMVPRVSMDALEVNETIAGV 225

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
             ++    HSR PV  E  D I G++  KD++P++R+      +   +R+A+ VPE+ +V
Sbjct: 226 ASLMQNWEHSRIPVFRETPDDIVGVVYLKDMIPYLRAGKMDTPLSAFMRRALFVPETMKV 285

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
             +    R +  H A+V+DE+GG +G+VT+ED+LE IVG+I DEYD E+     QL+ ++
Sbjct: 286 ADLFGMMRGKHVHFAVVVDEYGGTAGIVTLEDLLEEIVGDIRDEYD-EESAPIVQLNENS 344

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           + V+   S+ED     G  F   +VD++GG V+  F   P +G+    D +  KV     
Sbjct: 345 YRVKCTESLEDLGAVVGYDFDCNDVDSVGGYVLDKFMGFPEKGDIYRDDDWTIKVTDVGE 404

Query: 272 RRIIQVHVKIPDDSPQPK 289
            R+ +V         Q +
Sbjct: 405 HRVNEVIFTRSAHEVQKE 422


>UniRef50_C6IW85 Putative uncharacterized protein n=1 Tax=Paenibacillus sp. oral
           taxon 786 str. D14 RepID=C6IW85_9BACL
          Length = 452

 Score =  305 bits (782), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 77/272 (28%), Positives = 139/272 (51%), Gaps = 4/272 (1%)

Query: 14  NKKGFFSLLLSQLF--HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +     + L  +      +  + +EL  L+R+S  N  I++     +  +    D   +D
Sbjct: 157 SSGRIVAWLGLKPAADWDDAHSEEELRILLRESLANGRINKSEYRFMNRIFAFDDLLAKD 216

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM+PR+ M+ L   ++ +E L +I    ++RFPVI  +KD+I G++  K L      +  
Sbjct: 217 IMVPRTDMVCLDAAKSREENLRIIRREQYTRFPVIRGNKDNIIGVINTKALF-LAPENQA 275

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  ++R  + V E+  +  +L + + +R H+A++IDE+GG SG+VTIEDILE IVG+
Sbjct: 276 DVPLASLVRPVMTVSENIPLPALLTKMQKERSHIAVLIDEYGGTSGMVTIEDILEEIVGD 335

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DE+D E++ +  +++ +   V    S+   NE       +++ DTIGG +      + 
Sbjct: 336 IRDEFDAEEEQEITEVAANHLIVDGKVSVSLINELLDADLKEDDADTIGGWIYGHNLDI- 394

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
             G  +     QF V   +  RI ++ +K  D
Sbjct: 395 EEGTQLVYGDLQFTVLEREDTRIRKIEIKRLD 426


>UniRef50_B0MHL2 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=B0MHL2_9FIRM
          Length = 443

 Score =  304 bits (781), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 75/277 (27%), Positives = 139/277 (50%), Gaps = 5/277 (1%)

Query: 13  SNKKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           ++      +L  +    E     +E+  ++    +   ID + ++ +E V +  D    D
Sbjct: 164 ASTNIVLKILHMKTEAEEQTVTEEEIRLMMELGEEKGTIDSEEKEWIENVFEFGDTTAGD 223

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
            M   S++  +   Q+ +E L++I E+  SRFPV ++  + I GIL A+D L  +  + E
Sbjct: 224 HMTHSSEVTAVSLAQSAEEILNIIRETGLSRFPVYAKGFNDIRGILNARDFLMNLNENRE 283

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
             +++++LR A  VPE+     + ++ + ++ H+A+VIDE+G VSG+VT+ED+LE IVG 
Sbjct: 284 K-TLEEMLRPAYFVPETIPSSVLFQDMQKKKIHLAVVIDEYGEVSGIVTMEDLLEEIVGN 342

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHL 250
           I DE+D  +     + + + W       +    E  G    D  + DT+GGLV      +
Sbjct: 343 IYDEFDPSEPPKISKAAENLWKCSGAVKLNTIAEELGVEIPDHPDYDTLGGLVFSRLHSI 402

Query: 251 PARGETIDID--GYQFKVAMADSRRIIQVHVKIPDDS 285
           P  G T +++  G    V     R+I++  ++   + 
Sbjct: 403 PKDGTTFELEICGLHIHVKKMMGRKIVEAEIQKRKNP 439


>UniRef50_A3EP54 Putative uncharacterized protein n=2 Tax=Leptospirillum sp. Group
           II RepID=A3EP54_9BACT
          Length = 455

 Score =  304 bits (781), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 74/277 (26%), Positives = 141/277 (50%), Gaps = 4/277 (1%)

Query: 13  SNKKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +  +G   +L  +      P + +EL  L+++  +  +I+   +D+++ V    D  VR+
Sbjct: 162 ATSQGLLRMLGVRNSRSAYPISPEELDLLLKEGTEQGVINRTEQDLIQSVFKFTDISVRE 221

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M+PR +M+ +  + T+++  + + +   SR+PV+      + GIL  KDL        +
Sbjct: 222 VMVPRMKMVVMDASMTIEQATNFLSDHRFSRYPVVRTGTGEVVGILYYKDLFENYVRSRQ 281

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  ++     +PES +V   LKE + +R  MA+V+ E+G + GLVT+ED+LE +VGE
Sbjct: 282 G-RLTDLVHAPFFIPESMKVAHTLKEMQKRRTQMALVLSEYGTLEGLVTMEDLLEELVGE 340

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHL 250
           IEDE D+       +L   ++ V A  SI D  E +     + ++ +T+ G V+     +
Sbjct: 341 IEDESDDIQKP-VERLRDGSYLVDASQSIRDLREDYHLDIPEGDDYETLAGFVVAQLQTI 399

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           P  GE   ++  +  +   D  R+ +V ++   D P 
Sbjct: 400 PRGGEFFYMNHLKVTIVDMDKYRVSRVKIEPVPDMPD 436


>UniRef50_A6CBK3 Hemolysin protein n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CBK3_9PLAN
          Length = 436

 Score =  304 bits (781), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 90/265 (33%), Positives = 151/265 (56%), Gaps = 7/265 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+L+++ +  +  +++ +   M++ VM++ D+ V  IM  R  M  +  N TLDE L  
Sbjct: 171 EEILSVVEEGARGGILESEAGKMIQRVMELQDEDVGAIMTQRMDMEYISVNATLDEALLK 230

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD------AEAFSMDKVLRQAVVVPES 148
            I+  HSR PVI E  D I GIL A++LL     +       E  ++ K++     +PE+
Sbjct: 231 FIDVGHSRIPVIGESTDDIVGILYARELLKHFSKENQNSESPEELTIQKLMFSPFYIPET 290

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             +D +L+  + +  HMAIVIDE+GGV+GLVT+ED+LE IVG+I DE+DEE++    +  
Sbjct: 291 TGIDSLLETMQKEHVHMAIVIDEYGGVAGLVTMEDVLEEIVGDIVDEFDEEEEQMIFETG 350

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDIDGYQFKVA 267
           ++T  V A   I+D NE +  +  +  + DTIGG V+   G +P  GET+     + +V 
Sbjct: 351 QNTLEVDARVHIDDLNEQYNYNLPEGKDFDTIGGFVITQIGKVPQPGETLTWQQLRIEVL 410

Query: 268 MADSRRIIQVHVKIPDDSPQPKLDE 292
            +D RRI ++ +++     +    +
Sbjct: 411 ESDERRINKLRIELDTSLVEEYDTD 435


>UniRef50_C5EUB4 Membrane-anchored CBS domain-containing protein-domain containing
           protein n=5 Tax=cellular organisms RepID=C5EUB4_9FIRM
          Length = 496

 Score =  304 bits (780), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 80/291 (27%), Positives = 149/291 (51%), Gaps = 17/291 (5%)

Query: 12  ISNKKGFFSLLLSQLFH------GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIA 65
           ++      S L+ +LF        +    +++++++ +  +  +++ D  +M+  + ++ 
Sbjct: 160 LTRLITLVSALVLRLFGVDIADDDDNVTEEDIMSMVNEGHEQGVLEADETEMITNIFELG 219

Query: 66  DQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA-HSRFPVISEDKDHIEGILMAKDLLP 124
           D+   DIM  R+ M  L  +  L + +  I+    ++R+PV  ED D I GIL  +D + 
Sbjct: 220 DKEASDIMTHRTNMTALDGSMLLGDAVHFILNEGINTRYPVYREDIDDIVGILHMRDAMV 279

Query: 125 FM----RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           ++      D     +  +LR+A  +PE++ +D + KE +S + HM IV+DE+G  +GL+T
Sbjct: 280 YVEMEEYKDRPLLEVPGLLREANFIPETRSIDTLFKEMQSGKIHMEIVVDEYGQTAGLLT 339

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VD 237
           +EDILE IVG I DEYDEE+D         ++ +  L  ++D  +     F +E+    D
Sbjct: 340 MEDILEEIVGNIMDEYDEEED-FISVREDGSFIMSGLTPLDDVMDVLDIEFPEEDSDTYD 398

Query: 238 TIGGLVMQAFGHLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
           T+ G ++     +P  GE   +   GY F+V  A ++ I  +HV    +  
Sbjct: 399 TLNGYLISRLDRIPQEGENPRVGFGGYTFEVIKAGNKMIESIHVFKDQEEE 449


>UniRef50_B2V0V1 CBS/transporter domain protein n=18 Tax=Clostridiales
           RepID=B2V0V1_CLOBA
          Length = 439

 Score =  304 bits (780), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 85/277 (30%), Positives = 156/277 (56%), Gaps = 5/277 (1%)

Query: 13  SNKKGFFSLLLSQLFH-GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           ++     SL         E  +++E+ +L+    ++ +I+E  ++M+  + +  D+   +
Sbjct: 164 ASTNILVSLAGLDKEGLDEKVSKEEIKSLVEVGQEHGVINETEKEMINSIFEFDDKLADE 223

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKD-LLPFMRSDA 130
           +M PR+++  +  ++ L+E LD ++E  +SR PV  ED D+I GIL  KD +L   + + 
Sbjct: 224 VMTPRTEVYLINIDKPLEEYLDELLEEKYSRVPVYEEDIDNIIGILYMKDFILEARKHEF 283

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           E  ++ ++L     VPE+K +D +  E +S + HMAI+IDE+GG SG+VTIED++E ++G
Sbjct: 284 ENVNIREILHPPYFVPETKNIDDLFNELKSSKKHMAILIDEYGGFSGIVTIEDLVEEVMG 343

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
            I+DEYD E++   +++  +T+ V  L  I+D N+        +E DTI G ++   G +
Sbjct: 344 NIDDEYD-EEECFVQKIDSNTFIVNGLMPIDDLNDYLHIQLVSDECDTISGFLINIMGKI 402

Query: 251 PARGET--IDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           P   E   I+ +   FK+     +RI ++ + I  D 
Sbjct: 403 PNNIEEKVIEYENIIFKIESIKEKRIEKIKICIQKDK 439


>UniRef50_C3L2Y2 Transporter, HlyC/CorC family n=26 Tax=Bacteria RepID=C3L2Y2_CLOB6
          Length = 447

 Score =  304 bits (780), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 72/249 (28%), Positives = 137/249 (55%), Gaps = 3/249 (1%)

Query: 40  LIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESA 99
           +I    +  + +   ++M+  + D  +   ++IM PR+ + T+  N +    ++ ++E  
Sbjct: 195 MIDLGEETGVFNSTEKEMINSIFDFDNTLAKEIMTPRTSVFTMDINDSPKNIINNMLEER 254

Query: 100 HSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EAFSMDKVLRQAVVVPESKRVDRMLKEF 158
           +SR P+  ED D+I GIL  KD+L  +  +  +   +  +LR    +PE+K +D + KE 
Sbjct: 255 YSRVPIYDEDIDNIIGILHIKDILSIINKENIKKEDLINILRIPYFIPETKAIDFLFKEM 314

Query: 159 RSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA 218
           ++ + ++AI+IDE+GG SG+VT+ED++E ++G I DEYDE+   +  ++  +T+ + A  
Sbjct: 315 QTSKNYIAILIDEYGGFSGIVTMEDLIEEVMGNIFDEYDEDHTEEIIKMDANTFLLDASI 374

Query: 219 SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA--RGETIDIDGYQFKVAMADSRRIIQ 276
           +I+D NE        E  DT+GG ++   G +P       I  +   FK+    + RI +
Sbjct: 375 TIDDLNEKLNLELPSENFDTLGGFILDITGTIPKCNVNSEIQYNNLIFKIEKVSNNRIEK 434

Query: 277 VHVKIPDDS 285
           + + I + S
Sbjct: 435 IKLYINEKS 443


>UniRef50_B9L251 Magnesium and cobalt efflux protein corC n=1 Tax=Thermomicrobium
           roseum DSM 5159 RepID=B9L251_THERP
          Length = 420

 Score =  304 bits (779), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 89/236 (37%), Positives = 136/236 (57%), Gaps = 1/236 (0%)

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           ++E V+ +     RDIM+PR+ ++ +    ++ + + V  ++ HSR PV     D I GI
Sbjct: 183 LIERVLRLDRLTARDIMVPRTDIVAVPFELSVRDAIAVARQTRHSRLPVYQGTIDRIVGI 242

Query: 117 LMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           +  +DLL F    AE   +  V+R+A  +PESKRVD +L++ + QR HMAIV+DEFGG +
Sbjct: 243 VHVRDLLRFALESAEGIKVGDVMREAYFIPESKRVDELLRDLQHQRVHMAIVVDEFGGTA 302

Query: 177 GLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEV 236
           G+VTIED+LE IVGEI+DEYD  +     +LS     V    S+E+  + FG    +EE 
Sbjct: 303 GIVTIEDVLEEIVGEIQDEYD-AEAPLVERLSADEAIVDGRISLEEIADIFGVSLEEEES 361

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            TIGGLV    G +P  GE++ +DG +  V      R+ ++ V+    S     ++
Sbjct: 362 STIGGLVQAHLGRIPQPGESVRVDGLEVTVLEVAGNRVRKLSVRRVAASVSASDED 417


>UniRef50_UPI0001BCCCA8 CBS domain-containing protein n=1 Tax=Aeromicrobium marinum DSM
           15272 RepID=UPI0001BCCCA8
          Length = 438

 Score =  304 bits (779), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 91/273 (33%), Positives = 153/273 (56%), Gaps = 6/273 (2%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
                 G   +  E+  L+  +  + LI+ D   M++ V ++ D  VR++M+PR+ ++ +
Sbjct: 158 GRGFSEGPFASEVEVRELVDLAAASSLIESDESKMIQSVFELGDTIVREVMVPRTDIVFI 217

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD---AEAFSMDKVL 139
           ++++TL + + + + S +SR PV+ ++ D + G+   KD+   +  +     A  +  +L
Sbjct: 218 EQHKTLRQSMSLALRSGYSRLPVVEDNLDDVVGMAYLKDVTKRVFDNHTAEHAERVSSIL 277

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
           R  + VP++K  D +LKE ++QR H+AIV+DEFGG +G+VTIEDILE IVGEI DEYD E
Sbjct: 278 RPCLFVPDTKHADELLKEMQAQRTHVAIVVDEFGGTAGMVTIEDILEEIVGEITDEYDTE 337

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
            D +   L   +W V +   ++D  E  G    DE+VD++GGL+ +  G +P  G  I I
Sbjct: 338 PD-ELEVLVDGSWRVSSRYDVDDLAELTGVDLQDEDVDSVGGLLAKHLGKVPIPGSAIVI 396

Query: 260 DGYQFKVAMADSR--RIIQVHVKIPDDSPQPKL 290
           +G +        R  RI +V V    +   P+ 
Sbjct: 397 EGLRLVAEAPSGRRNRIGRVLVTRLTEDDDPES 429


>UniRef50_C7DFD3 CBS domain protein n=6 Tax=Rhodobacteraceae RepID=C7DFD3_9RHOB
          Length = 456

 Score =  304 bits (779), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 79/281 (28%), Positives = 145/281 (51%), Gaps = 12/281 (4%)

Query: 16  KGFFSLLLSQLFHGEPK--NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +G   +   ++         R+E+   ++      +++++ RD + G +D+AD+ V +IM
Sbjct: 170 RGVLRIFGVKIDPDSNVLAVREEIQGALQLGHSEGVVEKEDRDRILGALDLADRTVEEIM 229

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM------- 126
           + RS +  +    T ++ L+  + S H+R P+  ++ ++I G++ AKDLL  +       
Sbjct: 230 LHRSGIEMIDAGNTPEDILNQCLASKHTRLPIYKDEPENIIGVIHAKDLLRAVNTLLRTP 289

Query: 127 ---RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIED 183
               S    F++ +V  +   VPE+  +D  +++F ++  H A+V+DE+G + GL+T+ED
Sbjct: 290 GEDASSLADFNVIEVAMEPYFVPETTPLDDQMRQFLARHTHFALVVDEYGALQGLITLED 349

Query: 184 ILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLV 243
           ILE IVGEI DE+D  +D    Q    T+ V    +I D N A      D+E +T+ GLV
Sbjct: 350 ILEEIVGEITDEFDGGEDNQLAQSDDGTFMVEGNMTIRDLNRANDWSLPDDEANTVAGLV 409

Query: 244 MQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           +     +P  G+     G++F+V      RI  + V+    
Sbjct: 410 IHEAQMIPTVGQVFSFHGFRFEVTEKQKNRIATLKVRPLQP 450


>UniRef50_C8WNW4 Putative uncharacterized protein n=1 Tax=Eggerthella lenta DSM 2243
           RepID=C8WNW4_EGGLE
          Length = 439

 Score =  303 bits (778), Expect = 4e-81,   Method: Composition-based stats.
 Identities = 82/286 (28%), Positives = 143/286 (50%), Gaps = 12/286 (4%)

Query: 13  SNKKGFFSLLLSQLFHGEPK-NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           S   G   +L   + +       +E+  LI +S ++ LID +  + ++ + D+ D+    
Sbjct: 159 SITNGVMKMLGHDVANEHEVYTDEEIKLLIDESTESGLIDPEQNEYVDNIFDLGDKDAEA 218

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM PR+ ++ +  +  L+E L  +++  ++R+PV    KD I G +  KDL   M  DA 
Sbjct: 219 IMTPRTDVVCIDLDDPLEESLQTVLQYKYTRYPVCRGSKDRIVGFVHVKDLYT-MPKDAT 277

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +   +R    VPE   + ++L+  + +R  +A+VIDE GG +G+VT+ DI+E IVG 
Sbjct: 278 VDDLR--VRMIQAVPEGVPIAKLLQTLQEKRTKIAVVIDEHGGTAGIVTMSDIMEQIVGR 335

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEEVDTIGGLVMQAFGHL 250
           I+DEY      +  QL   ++ +     I++  E  G      EE +T GGL++  F  +
Sbjct: 336 IDDEYAHGGSDEIVQLDDGSYLIDGSLPIDEVGELIGFEPLESEECETAGGLLLTVFDRI 395

Query: 251 PARGETIDIDG----YQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           P  G+++ I+       F V   D  RI ++ V +      P+ DE
Sbjct: 396 PDEGDSVTIEDGDDRATFTVVDMDRHRIDKIRVVL---EHAPESDE 438


>UniRef50_A8KYW4 CBS domain containing protein n=33 Tax=Actinomycetales
           RepID=A8KYW4_FRASN
          Length = 484

 Score =  303 bits (777), Expect = 5e-81,   Method: Composition-based stats.
 Identities = 98/262 (37%), Positives = 150/262 (57%), Gaps = 5/262 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
           G   +  EL  L+  + +N++I+ + RDM+  V ++ D  VR++M+PR  M+ ++ ++T+
Sbjct: 163 GPFASEAELRDLVDLAEENEVIEPEERDMIASVFELGDTLVREVMVPRPDMVFIESDKTV 222

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
            + + + + S  SR PVI E  D + GI   KD++ + R   E+  + +V+R  V+VPES
Sbjct: 223 RQAISLALRSGFSRIPVIGESIDDVVGIGFLKDMVGWEREGRESSRVAEVMRPPVLVPES 282

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
           K  D +L+E ++ R HMAIVIDE+GG +GLVTIED+LE IVGEI DEYD         L 
Sbjct: 283 KPADDLLREMQASRTHMAIVIDEYGGTAGLVTIEDVLEEIVGEITDEYDSATPP-VEWLD 341

Query: 209 RHTWTVRALASIEDFNEAFGT-HFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
             T  V A   ++D  + FG       ++V+T+GGL+  A G +P  G T D+ G +   
Sbjct: 342 DDTARVTARLDVDDLADLFGVEELPGAQDVETVGGLLANALGRVPIPGATADVAGLRLSA 401

Query: 267 AMADSRR--IIQVHVKIPDDSP 286
             A  RR  I  V V     +P
Sbjct: 402 ERAAGRRNQIGTVVVHRLSPAP 423


>UniRef50_D2LDC4 Putative uncharacterized protein n=1 Tax=Rhodomicrobium vannielii
           ATCC 17100 RepID=D2LDC4_RHOVA
          Length = 428

 Score =  302 bits (776), Expect = 8e-81,   Method: Composition-based stats.
 Identities = 85/284 (29%), Positives = 138/284 (48%), Gaps = 13/284 (4%)

Query: 10  DTISNKKGFFSLL----LSQLFH----GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGV 61
            TIS    FF  L    + +L            +E+ ++I +  +  + ++  ++++E V
Sbjct: 146 ATISTPISFFLRLSTDAVLRLAGPMKAEPEVTEEEVKSMIAEGTEAGVFEKAEQEIIERV 205

Query: 62  MDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKD 121
           + +AD+ VR IM+PR  +I L  N + +   + I  S HSRFPV  +D D   G++ AK 
Sbjct: 206 LSVADRSVRSIMVPRRDIIWLDVNDSEEAIFNDIFSSGHSRFPVCRDDVDETFGVIHAKT 265

Query: 122 LLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
           LL   R   +  +++  +   + V ES  V ++L+ F++   HMAIV+DE G V G+VT 
Sbjct: 266 LLEQCRHGGK-INLEAAIMAPLYVHESTNVLKLLEMFKNTLVHMAIVLDEHGTVQGIVTP 324

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH---FSDEEVDT 238
            DIL  I GE+ +E  +       Q    +W + A   + +       +     D E  T
Sbjct: 325 ADILAGIAGELPEEEADIGQSAV-QREDGSWLLDAQMPVYEVERVLDVNGMAVDDAEYTT 383

Query: 239 IGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           + G V+   GH+PA GE      + F+V   D RRI +V    P
Sbjct: 384 LAGFVLAQLGHIPAVGEKFRWRSWVFEVIDLDGRRIDKVLAFRP 427


>UniRef50_Q7VRA4 Haemolysin-related protein n=2 Tax=Candidatus Blochmannia
           RepID=Q7VRA4_BLOFL
          Length = 291

 Score =  302 bits (775), Expect = 9e-81,   Method: Composition-based stats.
 Identities = 163/285 (57%), Positives = 221/285 (77%), Gaps = 2/285 (0%)

Query: 4   DNSHSSDTISN--KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGV 61
           +N++  ++I +  KK FF+L+L  LF    +NR++LL LIRD  +N LID DT+DMLEGV
Sbjct: 2   NNNYLEESIHSVRKKNFFALILKHLFRENFRNRNDLLNLIRDFEKNALIDSDTKDMLEGV 61

Query: 62  MDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKD 121
           ++I +Q+VRDIMIPRSQ+I LK  Q+ DE L +II+S+HSRFPV++ED D I+GIL+AKD
Sbjct: 62  LEIVEQKVRDIMIPRSQIIFLKNTQSWDEQLSIIIQSSHSRFPVLNEDLDQIKGILIAKD 121

Query: 122 LLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
           LLP +    + +++ ++LR A+VVPE+K VDRMLKEFR+Q  HMAIVIDEFG +SG++TI
Sbjct: 122 LLPLILKKNQPYNIGQILRPAMVVPENKGVDRMLKEFRAQHCHMAIVIDEFGSMSGIITI 181

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGG 241
           EDILELIVG IEDEYD ++D +  Q++  T+ + AL  +E+FN  F T+F +EE+DTIGG
Sbjct: 182 EDILELIVGNIEDEYDNKNDCNIYQVNHRTFLINALTPVEEFNIKFNTNFYNEEIDTIGG 241

Query: 242 LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
            VMQ FGHLPARGE+IDI GY FK+ + D+ RIIQ+ V+IP +  
Sbjct: 242 FVMQTFGHLPARGESIDISGYIFKITVTDNHRIIQLLVQIPKNEH 286


>UniRef50_B9ZL46 CBS domain containing protein n=2 Tax=Gammaproteobacteria
           RepID=B9ZL46_9GAMM
          Length = 311

 Score =  302 bits (775), Expect = 9e-81,   Method: Composition-based stats.
 Identities = 135/295 (45%), Positives = 194/295 (65%), Gaps = 6/295 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLE 59
           M +       T      +     ++L    +P  R EL+  +RD+   +L+D +   MLE
Sbjct: 1   MPEPVPDEQPTWRR---WLERAKTRLWPRRDPATRRELIETLRDAHGRELVDPEALTMLE 57

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
           GV+++AD +VRDIMIPR+QM  ++R+  L E L  ++ SAHSR PV+ + +D + G+L+A
Sbjct: 58  GVLNVADMQVRDIMIPRAQMEVVRRDARLSEFLPDVVASAHSRLPVVGDHRDEVVGVLLA 117

Query: 120 KDLLPFMRS-DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           KDLL F    D  AF M ++LR AV VPESKR++ +LKEFR  R HMAIV+DE+GGV+GL
Sbjct: 118 KDLLRFFGEPDDAAFDMQEILRPAVFVPESKRLNVLLKEFRLSRNHMAIVVDEYGGVAGL 177

Query: 179 VTIEDILELIVGEIEDEYDEEDDI-DFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           VTIED+LE IVGEIEDE+D ED +    Q     +T++AL  +E+FN  F T +S+++ D
Sbjct: 178 VTIEDVLEQIVGEIEDEHDVEDYLTQIMQHPGGRYTIKALTPMEEFNAYFQTAYSEDDFD 237

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           TIGGLV+  FGH+P RGE I IDG +F+V  AD+RR+  + +++P+    P  D+
Sbjct: 238 TIGGLVLSHFGHVPRRGEQIVIDGMRFRVLRADNRRLHLLEMRLPEPDVAPASDD 292


>UniRef50_C6W3X5 Putative uncharacterized protein n=1 Tax=Dyadobacter fermentans DSM
           18053 RepID=C6W3X5_DYAFD
          Length = 430

 Score =  302 bits (774), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 86/272 (31%), Positives = 144/272 (52%), Gaps = 4/272 (1%)

Query: 15  KKGFFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
                        HG E  + DEL  L++    + +I+    D+++   D +++  R IM
Sbjct: 161 ANVILKGFGITPSHGSEVHSSDELRYLVQQQKDSGMIEAADYDLIKNAFDFSERIARQIM 220

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR Q++ +  N   +  L+ +IE  +SR PV  +  D + G+L  KDLL  MR   +  
Sbjct: 221 IPRPQVVGIDVNDFTEAKLEKVIEEGYSRMPVYEDTLDQVIGVLHLKDLLLKMRQGKDIV 280

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + +++R    V  SK +  +L+EF+  R  MA+++DE+GGV G+VT+EDILE +VGEI+
Sbjct: 281 -LRELIRPIATVHGSKPIGALLREFQVSRQQMAVIVDEYGGVDGIVTMEDILEELVGEIQ 339

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPA 252
           DEYD  +    +  S +T+TV+  ASI D N+      +   + +T+ G ++   G +PA
Sbjct: 340 DEYD-NEAPIVKNESDNTYTVQGAASIADLNDKLPHDITRRPDYETLAGYLIWKCGRIPA 398

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
            GE +    Y+F V       + QV + + + 
Sbjct: 399 VGEKVKTKHYEFTVLKKQRSSVTQVKIAVLES 430


>UniRef50_B5Y9X2 CBS domain protein n=1 Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y9X2_COPPD
          Length = 434

 Score =  301 bits (773), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 81/271 (29%), Positives = 146/271 (53%), Gaps = 4/271 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           +  L + +    +ELL ++          ++  +M++ V++ +D  VR+IM PR  +  L
Sbjct: 164 VGSLEYTKVVTDEELLRIVERGRSEGQFLQEEEEMIKSVLEFSDTTVREIMTPRLAVFWL 223

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQA 142
            +N  ++E L ++++S +SR  +     D++ G++  KDL+          S++ + R  
Sbjct: 224 DKNVGVNEALQLMLDSGYSRALLCDGSLDNVLGVIHIKDLMKLHVQGDSEGSLESIKRDV 283

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
           + VPE++ ++ +  + R  R H+A+V+DE+G V+G+V++EDILE +VGEI DEYD+E++ 
Sbjct: 284 LFVPETEMINEVFFQMRRLRNHLAVVVDEYGAVAGVVSLEDILEELVGEIRDEYDQEEEP 343

Query: 203 D-FRQLSRH--TWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
               + S +     V    S+ D N+        EEVDTI G V+    H P  GE   +
Sbjct: 344 IRIVEKSENYVKAIVLGHVSLGDVNDVLDLDLEAEEVDTIAGFVLLQLQHFPEVGEKFRL 403

Query: 260 DGYQFKVAMADSRRIIQVHVKI-PDDSPQPK 289
           DG +F V    ++RI +V ++    +  QP 
Sbjct: 404 DGTKFTVLSVTNKRIDKVLIEREISEEDQPS 434


>UniRef50_Q1K126 CBS domain protein n=2 Tax=Desulfuromonadales RepID=Q1K126_DESAC
          Length = 282

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 90/282 (31%), Positives = 163/282 (57%), Gaps = 4/282 (1%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           T   ++ +   LL    H    + + L  LI  S +  +I+ +  +M   + +  +  VR
Sbjct: 4   TPETRRSWLQRLLGITHHVT--SEEHLQELIHASEEGGIINAEEGEMFSSIFEFGETIVR 61

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           ++MIPR++M +   + +LD  ++++++  HSR PV  E  D I G++ AKDLL F    +
Sbjct: 62  EVMIPRTEMRSCPVDASLDTFIEMVLKFGHSRIPVYEETIDRIVGLVYAKDLLKFWGQPS 121

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
              S+  ++R+   VPE+KR++ +L+EFR+QR H+AI IDE+GG SGL+T+ED++E I+G
Sbjct: 122 HEISLRDLMRKPYFVPETKRIEELLQEFRTQRMHIAIAIDEYGGTSGLITLEDLIEEIIG 181

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEEVDTIGGLVMQAFGH 249
           +I+DEYD +D+    +    T  V A  S+++  + +    F  ++ D++GGL++   G+
Sbjct: 182 DIKDEYDFDDNQLIEETP-GTIVVDARLSLDELEDHYDLPEFERDQFDSVGGLLLHRLGY 240

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           +P  GE + ++  +  V  +D R I ++ V   +   +P  D
Sbjct: 241 VPKPGEEVVVEPLKMVVLQSDERMIHRIRVIREESPEEPLDD 282


>UniRef50_A4FLP3 Magnesium and cobalt efflux protein CorC n=3 Tax=Actinomycetales
           RepID=A4FLP3_SACEN
          Length = 426

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 78/273 (28%), Positives = 136/273 (49%), Gaps = 6/273 (2%)

Query: 14  NKKGFFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +      L+        +   ++EL  ++R + Q   +  + R +L    +  D+ + ++
Sbjct: 157 STNAVVRLVGIDPRSDADKVTQEELRDMVRTNEQ---LTVEERKLLTDAFEAGDRVLSEV 213

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE- 131
           MIPR+++  L R  +L + +  + +  HSR+PVI +  D + G L  +DLL     +   
Sbjct: 214 MIPRTEVDFLDRTMSLADAVAKVRDQPHSRYPVIRDTADDVVGFLHVRDLLTTTHDNRSG 273

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
           A ++  + R    +P SK V   L   R +  H+A+V+DE+GG +G+VT+ED++E +VGE
Sbjct: 274 ARTIGDLARPVTSLPGSKPVLSALTVMRRRGGHLAVVVDEYGGTAGIVTVEDLVEEVVGE 333

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DEYD       R     ++ +  +    +  E  G    D   DT+ G VM   G +P
Sbjct: 334 IWDEYDTGVAP-VRPSPEGSYELDGMLHRSEVEEHTGISLPDGPFDTLAGFVMAELGRMP 392

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           A G+ ++  G++F V   D RRI +V +    D
Sbjct: 393 AEGDAVEALGHRFTVRELDGRRIARVLITPLGD 425


>UniRef50_C8VVX2 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C8VVX2_DESAS
          Length = 446

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 84/274 (30%), Positives = 149/274 (54%), Gaps = 8/274 (2%)

Query: 15  KKGFFSLLLSQLF--HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
                 ++  Q    H    +  EL  L+ +S ++  +D+D   +L+ V +   +  R+I
Sbjct: 170 ANSILHIIGIQRTSEHEASHSEKELQMLVSESYKSGHLDKDEWRLLQNVFEFEKRIAREI 229

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           ++PR +++ L R +TL + +++  +S H+RFP+   D D++ G++  KDL        + 
Sbjct: 230 LVPRPEVVFLDRRKTLQQNIEIARQSEHTRFPLCDGDNDNVVGLIHIKDLFKL----KDE 285

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
            S++ V R  ++VPE   +DR+LK+F+  R  MA+V+DE+GG SG+VT+ED+LE +VGEI
Sbjct: 286 TSINDVKRNIMMVPEGIPLDRLLKQFQQCRQQMALVVDEYGGTSGIVTMEDVLEKLVGEI 345

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLP 251
            DE+D  +          T+ V     +E+  E F    +++ E DTIGG V    G  P
Sbjct: 346 HDEFD-NEIPKIIPEKEGTFLVEGRLLLEEAKEMFHLPVTEDTEYDTIGGYVFGELGKRP 404

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
             G+ +++  ++ +V      RI Q+ + I D+ 
Sbjct: 405 KVGDIVELPNHRLEVTRIQGLRIQQIRLNILDNK 438


>UniRef50_Q1YQV9 Magnesium and cobalt efflux protein CorC n=1 Tax=gamma
           proteobacterium HTCC2207 RepID=Q1YQV9_9GAMM
          Length = 279

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 125/284 (44%), Positives = 190/284 (66%), Gaps = 5/284 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M+D+ + S+   S         +S +F   P++ +++  ++R +    +ID     ++EG
Sbjct: 1   MNDETTTSAAEKS-----IFKRISDVFSQTPRSSEDVADILRSAENESIIDASVLQIMEG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            + ++DQ+ R+IMIPRSQM+ +  + +L++ L V+I S HSRFPV+ E  D I+GIL+AK
Sbjct: 56  ALKVSDQQAREIMIPRSQMVIIDDDFSLEQVLKVVISSQHSRFPVVGESSDDIKGILLAK 115

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           ++LP + S  E+F +  +LR A ++PESKR++ +L+EFR QRYHMAIV+DE+GGVSGL+T
Sbjct: 116 EMLPLLLSGNESFDLKALLRPATIIPESKRLNVLLQEFREQRYHMAIVVDEYGGVSGLLT 175

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IEDILE IVGEIEDE DE ++   +  +  ++ V A+A + +FNE F    +D+E DT+G
Sbjct: 176 IEDILEEIVGEIEDETDEHEEAPIKATTSGSFNVEAIAEVSEFNEFFDVGLADDEFDTVG 235

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           GLV+ AFG LP   E+ID DG+ FKV   D+R+I Q+ V     
Sbjct: 236 GLVLHAFGRLPEINESIDFDGFTFKVTDGDNRKITQLEVTKITP 279


>UniRef50_Q2NIR0 Hymolysin-related protein n=5 Tax=Candidatus Phytoplasma
           RepID=Q2NIR0_AYWBP
          Length = 423

 Score =  300 bits (770), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 73/279 (26%), Positives = 145/279 (51%), Gaps = 8/279 (2%)

Query: 12  ISNKKGFFSLLLSQLFHGEPK--NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           ++     F ++     +      + DEL  ++  S Q  +ID+D   M++ + +     +
Sbjct: 143 LTQVSNLFLIVFGLNPNKNSIQISEDELRLMLISSYQKGIIDKDENKMIQNIFEFDHTNI 202

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
            ++M  R++++ +    T  E +  I    ++RFPV     D+I GIL  KD+  ++ S 
Sbjct: 203 FEVMRHRTEVVAIDVEITKKELIKTIQNEKYTRFPVYENSIDNIIGILHIKDIFNYLMSS 262

Query: 130 AEA--FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
                F + K +R+  +V +++    + +E +  + HMAIVIDE+GG +G++T ED++E 
Sbjct: 263 NTNKIFDLKKFIRKPYLVQDAQNTREIFREMKKNKTHMAIVIDEYGGTAGIITFEDLIEE 322

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           I+GEI DEYD E+ +  ++++++ + V   A +E+  E     F+ E+ DT+ G ++   
Sbjct: 323 ILGEISDEYDNEE-LMIKEVAKNEYIVNGFADLEEVAETIKLEFNTEDYDTLSGFLIGKL 381

Query: 248 GHLPARGE---TIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           G  P + +    I    ++FK+   + + I Q+ +   D
Sbjct: 382 GRCPNQNDKNTEIIYKNFKFKILKHNDKVISQIKISKID 420


>UniRef50_A8DJD8 CBS domain protein n=1 Tax=Candidatus Chloracidobacterium
           thermophilum RepID=A8DJD8_9BACT
          Length = 427

 Score =  300 bits (770), Expect = 4e-80,   Method: Composition-based stats.
 Identities = 77/289 (26%), Positives = 138/289 (47%), Gaps = 6/289 (2%)

Query: 9   SDTISNKKGFFSLLLSQLFHG------EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVM 62
              +   +        +           P   + + ALI    +  +I+ED  ++++ V+
Sbjct: 138 QPLVRPMRKLIQRFRVEPERSLVPDSTPPIEEESIQALIDVGEEAGIIEEDEGELIQSVI 197

Query: 63  DIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL 122
           + +D  VR+IM  R  +I+++ + T+ E  + +    HSR PV  +D D I G +  +D+
Sbjct: 198 EFSDTAVREIMTQRPDIISVRASATVREASETMTRERHSRLPVFEQDSDDIVGFVFIRDV 257

Query: 123 LPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIE 182
           L  +    +   +  ++R A  VPESK +  +L++ R     +A+VIDE+G V+GLVTIE
Sbjct: 258 LDCLLHGRDQEPVRNIVRPAYFVPESKGIADLLEDMRKASVQIALVIDEYGDVAGLVTIE 317

Query: 183 DILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGL 242
           DILE IVGEI+DE     + +    +   W V     I           S ++  T+ G 
Sbjct: 318 DILEEIVGEIQDEDQPSGEDEVLMETDGAWLVHGSTEIRKIELVTERELSSDDFQTVNGF 377

Query: 243 VMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           ++ A   +P+ GE   + G + +V  +D R I +  ++    +  P  +
Sbjct: 378 IVSALERVPSTGEHFIVRGLEVEVLESDGRAIRRARLRKAPQTSPPTEE 426


>UniRef50_C8XF87 CBS domain containing protein n=11 Tax=Bacteria RepID=C8XF87_NAKMY
          Length = 537

 Score =  300 bits (769), Expect = 4e-80,   Method: Composition-based stats.
 Identities = 99/296 (33%), Positives = 156/296 (52%), Gaps = 13/296 (4%)

Query: 4   DNSHSSDTISNKKGFFSLLL-----SQLFHGEPKNRD-ELLALIRDSGQNDLIDEDTRDM 57
                +  ++       L+       + F   P + D EL  L+  +G   +++E  R+M
Sbjct: 127 PTRALARLLAPVASLLILIGNAITPGRGFREGPFSSDIELRELVDIAGSRGVVEETEREM 186

Query: 58  LEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGIL 117
           L+ V D+ D  VR++M+PR++ + ++R++TL + L +   S  SR PV+ ED D I G+ 
Sbjct: 187 LQSVFDLGDTIVREVMVPRTETVWIERDKTLRQALALASRSGMSRIPVVGEDLDDIVGVA 246

Query: 118 MAKDLLPF---MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGG 174
             KDL+     +  D +   + +++R+ V VPESK VD +L+E +  R H A+V+DE+GG
Sbjct: 247 YLKDLIAPAMNLAPDDQGPVLTQIMREPVFVPESKNVDDLLREMQRDRTHFAVVVDEYGG 306

Query: 175 VSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE 234
            +G+VTIEDILE IVGEI DEYD +       L   ++ V A   +ED  E F     D+
Sbjct: 307 TAGIVTIEDILEEIVGEITDEYDADTPAPVVPLPDGSFRVSARLPVEDLGELFDVELDDD 366

Query: 235 EVDTIGGLVMQAFGHLPARGETIDIDGYQFK----VAMADSRRIIQVHVKIPDDSP 286
           EVDT+GGL+ Q  G +P  G  + + G        V      R+  V V+    + 
Sbjct: 367 EVDTVGGLLAQQLGRVPLPGSEVGVAGLFLHGEPGVDRRGRPRVQTVLVRRLTAAE 422


>UniRef50_D1AH17 Putative uncharacterized protein n=1 Tax=Sebaldella termitidis ATCC
           33386 RepID=D1AH17_SEBTE
          Length = 424

 Score =  300 bits (769), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 90/281 (32%), Positives = 151/281 (53%), Gaps = 4/281 (1%)

Query: 14  NKKGFFSLLLSQLFHGE--PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +   FFS L +   + +      D +   +    ++  I+E+ ++M+  ++D  D   ++
Sbjct: 145 SISKFFSRLFNVPINDDMFLITEDSIKTYVVQGKEDGAIEEEEQEMIHSIIDFTDTSAKE 204

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           I+ PR+ +  L+ N+ LDE  D II+   SR P+  E  D++ GIL +KDLL F R+  +
Sbjct: 205 ILTPRTSIFALEGNKCLDEVWDSIIDQGFSRIPIYEEQIDNVVGILYSKDLLKFDRTRDK 264

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              + ++ R A  +P +K +  +L+EFR ++ HMAIVIDE+GG  GLVTIED+LE IVGE
Sbjct: 265 DVKVSELKRDAYFIPGTKTLIELLEEFREKQNHMAIVIDEYGGTLGLVTIEDLLEEIVGE 324

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHL 250
           I DEYD E++ +  Q+    + ++    IE  N+    +    +E DTI G V    G +
Sbjct: 325 IRDEYDFEEE-NINQIKDEVFDIKGDTEIETVNKELDINIPISDEYDTIAGYVHYELGKV 383

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
               + ++ + Y  +V   DS RI +V +         + +
Sbjct: 384 AEVNDKVNGEDYVIRVLHLDSHRIDKVRIIKLVTEINEEDN 424


>UniRef50_C2MBP5 Gliding motility-associated protein GldE n=1 Tax=Porphyromonas
           uenonis 60-3 RepID=C2MBP5_9PORP
          Length = 452

 Score =  300 bits (769), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 95/279 (34%), Positives = 151/279 (54%), Gaps = 13/279 (4%)

Query: 20  SLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQM 79
            LL S+   G   + D+L   +  +      D    +M+  ++    +   +IM+PR  M
Sbjct: 173 KLLGSKARRGPELSVDDLSEAVALTTNG---DNKETEMIHEIVKFYHKTADEIMVPRVDM 229

Query: 80  ITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVL 139
           I +  +    + L   +++ +SR PV    +D I G+L  KDLLP M  + + F   K++
Sbjct: 230 IGVNYHWAYHQTLSFAVDTGYSRLPVYDGSQDSIRGVLYVKDLLPHMHEE-DTFPWQKII 288

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
           RQA  VPE+K++D +L+E + +R HMAIVIDEFGG SGL+T+EDILE IVGEI DEYD+E
Sbjct: 289 RQAYFVPENKKIDTLLEELQQERIHMAIVIDEFGGTSGLITLEDILEEIVGEIVDEYDDE 348

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD------EEVDTIGGLVMQAFGHLPAR 253
           D   + +L+   + +    S+ D  +       +      EEVDT+GGL ++    +P  
Sbjct: 349 DPP-YVRLAEGVYLIDGGMSLIDLCKLLDVE-PEYFAPHYEEVDTVGGLFLEVLQEIPQV 406

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKI-PDDSPQPKLD 291
           G+ I I    F V   +  RI+Q+ +++ P +    + D
Sbjct: 407 GQQITISDIDFIVTRMERHRIMQLKMRLHPKEQTDTQTD 445


>UniRef50_A2SJR8 CBS domain protein n=8 Tax=Burkholderiales RepID=A2SJR8_METPP
          Length = 439

 Score =  299 bits (768), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 69/278 (24%), Positives = 127/278 (45%), Gaps = 7/278 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      LL  +         +E+ A + +     +I+     M+  V  + ++++  +M
Sbjct: 157 STGAILGLLGIRDTQSRGVTEEEIAASLEEGFDAGVIEAQEHQMVRNVFRLDERQIGSMM 216

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR ++  L     + + L VI    HSR+PV     D + G++  + LL  + S  +  
Sbjct: 217 IPRGEIAWLDSTTPIADALAVIAAHEHSRYPVCRGGLDEVLGVVGTQHLLQQVTSG-KPL 275

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           S+ + L+  V VPE+     +L++FR     M  V+DE+G V G++T+ D+LE I GE  
Sbjct: 276 SLTEGLQPPVFVPETLTGMELLEQFRGSTTQMVFVVDEYGEVQGVITLRDVLEAITGEFT 335

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEE---VDTIGGLVMQAFGH 249
                 DD    Q    +W +  L  + +  +  G     DE+    +T+ G+ M   G 
Sbjct: 336 --TPTADDAWAVQRDDGSWLIDGLIPVPELKDRLGLKELPDEDRGRYNTLAGMTMLLLGR 393

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           LP   + ++  G++F+V   D +R+ +V V     +  
Sbjct: 394 LPQTADVVEWAGWRFEVVDLDGKRVDKVLVNRLGGADA 431


>UniRef50_C9KJP9 CBS domain protein n=3 Tax=Veillonellaceae RepID=C9KJP9_9FIRM
          Length = 458

 Score =  299 bits (767), Expect = 8e-80,   Method: Composition-based stats.
 Identities = 85/276 (30%), Positives = 139/276 (50%), Gaps = 6/276 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +  G   LL       +    DE+  LI    ++   ++  + M++ +  ++DQ    +M
Sbjct: 169 SAGGVLLLLGINPHVEDTVTEDEVKDLIEQGTEDGTFEKSEQAMVDRIFHMSDQTAYSLM 228

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR+QM+ L    +L   L +I E   + FPV  E+ D   G+L AKDLL       ++ 
Sbjct: 229 TPRTQMLWLDLTDSLRHNLRIIREHPQNVFPVGRENLDDFCGVLYAKDLLNASLE-RKSL 287

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + + +R+ + VP S    R+L +FR    H A+V+DE+GGV G +T+ DIL+ I+G+  
Sbjct: 288 DLAQYIRKPMFVPRSMETFRVLAKFRDTGIHEAMVLDEYGGVVGFITLNDILQEIIGDSM 347

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEE---VDTIGGLVMQAFGH 249
               E D I F     H+W V  L SI+DF E F      DE+     T+GG +   FG+
Sbjct: 348 SNV-EPDPIQFTPRDEHSWYVDGLCSIDDFKERFDIAELPDEDHDHYQTMGGFLTSYFGY 406

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           +P   E  + +G+ F+V   D  RI ++ V   +++
Sbjct: 407 IPKVAEKCEWNGFTFEVVDMDRARIDKILVTREENT 442


>UniRef50_Q609I4 CBS domain protein n=2 Tax=Proteobacteria RepID=Q609I4_METCA
          Length = 432

 Score =  299 bits (766), Expect = 9e-80,   Method: Composition-based stats.
 Identities = 62/277 (22%), Positives = 132/277 (47%), Gaps = 6/277 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      LL ++         +E+  L++      + +E  + ++E ++ +  ++V  IM
Sbjct: 157 STDIVLRLLGARPVRQPSVTEEEIKLLLQQGTLEGVFEEVEQKLVENILRLDSRKVGAIM 216

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR  ++ L   ++ +    ++ +  H   P+     D++ G +  KD+L  + +  +  
Sbjct: 217 TPRKDVVYLDVTKSYEANRGILTDHPHWIIPLCRGGVDNVLGFVKTKDVLNRLLAGEKP- 275

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + +++ +A+ VP S  + ++L+ F+      A+V+DE+G ++GLVT+ D+LE IVG I 
Sbjct: 276 ELAELVTRALFVPNSLSLMQLLEHFKRSHLQTALVVDEYGELTGLVTLTDVLEAIVGAIA 335

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFGH 249
            E   E++    Q    +W +  +  IE F + F      +EE     T+ G VM   G+
Sbjct: 336 SET-AEEEPQVSQREDGSWLIDGMLDIERFKQLFDLDALPEEETGNFHTMAGFVMLRLGN 394

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
           +P   ++ +    +F+V   D  R+ ++ V     + 
Sbjct: 395 VPKVTDSFEFQDLRFEVVDMDRNRVDKILVTRLPPAA 431


>UniRef50_C7NDD7 CBS domain containing protein n=3 Tax=Leptotrichia
           RepID=C7NDD7_LEPBD
          Length = 427

 Score =  299 bits (766), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 75/258 (29%), Positives = 141/258 (54%), Gaps = 2/258 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              DE+L  ++   ++ + +E   +M+  + + ++  V++I+ PR  +  L+    +D+ 
Sbjct: 171 ITEDEILTFLKAGTESGVFEEGEEEMITSIFEFSETTVKEILTPRRDVFALEAESKIDDV 230

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
            + I++   +R P+ +E  D I G +  KDLL + +   E   +   +++A  VP +K +
Sbjct: 231 WNEILDQGFTRIPIYTETIDKIVGTVHMKDLLRYDKQTGENPPIKDFMKEAYFVPITKPL 290

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
             +L+EF+ ++ HMAIVIDE+GG  G+VTIED+LE IVGEI DE+D+E++ + +Q+    
Sbjct: 291 VELLEEFKLKQLHMAIVIDEYGGTQGIVTIEDLLEEIVGEIRDEFDQEEE-NIQQIREKI 349

Query: 212 WTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMAD 270
           + ++    IE+ N+         EE DTI G +    G +    + +  D +  KV   D
Sbjct: 350 FDIKGDTPIEEINDKLEIEIPLSEEYDTISGYIQDKLGKVADVFDQVKGDNFVLKVTDVD 409

Query: 271 SRRIIQVHVKIPDDSPQP 288
           ++R+ +V   I +   + 
Sbjct: 410 NKRVERVRAVIIEQEKEE 427


>UniRef50_B6JNY8 Hemolysin domain-containing protein n=23 Tax=Campylobacterales
           RepID=B6JNY8_HELP2
          Length = 445

 Score =  298 bits (765), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 77/269 (28%), Positives = 143/269 (53%), Gaps = 3/269 (1%)

Query: 18  FFSLLLSQLF-HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
           F   +      H    + +EL  ++ +S +  +ID    ++++  +D +D   ++IM PR
Sbjct: 177 FLKKVGINPKEHDGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPR 236

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
             M+ L    + +E +D++++S  +R+P     KD+I G++  +DLL       +    +
Sbjct: 237 KDMVCLDEENSYEENIDIVLKSRFTRYPYCKGSKDNIIGMVHIRDLLSRSIFTPKMHDFN 296

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
           +++R+ ++VPES  + ++L + + ++ H A+VIDE+GG +GL+T+EDI+E I+GEI DEY
Sbjct: 297 QIVRKMIIVPESASISQILIKMKKEQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEY 356

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGE 255
           D + +    +L    + +  +  +E   E     F  E E  T+GG V      +P  G+
Sbjct: 357 DLKQE-GVNKLEEGVFELEGMLDLESVEEVLHIEFDKECEQVTLGGYVFSLLERMPMEGD 415

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           TI   GY F+V   D  RI ++     + 
Sbjct: 416 TIVSHGYSFEVLSVDGARIKRLKASKENK 444


>UniRef50_A9F240 Conserved hypothetical membrane protein n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9F240_SORC5
          Length = 430

 Score =  298 bits (764), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 89/281 (31%), Positives = 154/281 (54%), Gaps = 8/281 (2%)

Query: 12  ISNKKGFF-SLLLSQLFHGEP---KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           ++   G+  S L  +             E+  L+ +  ++ L   +  +M+  V++ AD 
Sbjct: 143 LAVPLGWIGSKLGPRDGEQPSDPRVAEAEVEILVDEVERSGLFGREPAEMIRNVLEFADL 202

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
             RD+M+PRS++  ++ +  L++ L+++ ES HSR+PV  +  D+I G+L AKDL   + 
Sbjct: 203 TARDVMVPRSKVEAIEISTPLEKVLEIVTESGHSRYPVYKDQTDNIAGLLYAKDLFKVLE 262

Query: 128 SDA-EAFSMDKVLR-QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDIL 185
               +  ++ ++ R  A  V ES+ +  +L+E +S+R H+AIV+DEFGG+SG+VT+ED+L
Sbjct: 263 ERRLKNTTLREITRSPANFVAESQPLSSLLREMKSRRQHLAIVVDEFGGMSGIVTLEDVL 322

Query: 186 ELIVGEIEDEYDEEDD-IDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLV 243
           E IVG+I DE+DE DD    + L        A  S+ D +   G     + + D++GG++
Sbjct: 323 EEIVGDIRDEHDETDDGAAIQDLGDGRLVADAAVSMSDLSAYLGAELDREGKYDSLGGML 382

Query: 244 MQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
            Q  G +P  G  +   G +F V  +D R I +V +  P  
Sbjct: 383 TQHVGKVPEVGTAVSKFGLRFIVRDSDERHIGKVEIVRPRA 423


>UniRef50_A4EBJ7 Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens
           ATCC 25986 RepID=A4EBJ7_9ACTN
          Length = 457

 Score =  297 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 79/279 (28%), Positives = 145/279 (51%), Gaps = 7/279 (2%)

Query: 15  KKGFFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
             G   +L  +     +  + +E+  ++    + D + ++ + M+  + D+ D   R++M
Sbjct: 163 SDGLARILRIKSADDRQNVSEEEIKYMVS---EQDDLLDEEKRMIHEIFDLGDTVAREVM 219

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           +PR      + ++T+ + L  + ++  SR PV  ED D++ GI   KDL+          
Sbjct: 220 VPRVDTTMCEDDETVADVLSTMRQTGFSRIPVYHEDPDNVAGIAHIKDLIQPALDGKGDQ 279

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            +   LR A  VP++K +  +L E ++    + +V+DE+GG +G++TIEDI+E IVGEIE
Sbjct: 280 PIAGFLRDATFVPDTKDILPLLSEMQTSHDQIVVVVDEYGGTAGIITIEDIVEEIVGEIE 339

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPA 252
           DE+D  D+    +LSR  W V    S +D  E  G    + ++ +TI G +++    +P 
Sbjct: 340 DEFD-PDNKYLTRLSRREWLVDGRFSCDDAIE-LGWPLEESDDYETIAGWILELCDSVPD 397

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
            GE  ++ GY+FKV     +RI  + V  P ++ +   +
Sbjct: 398 IGEVFEVAGYKFKVQSMRGQRISLIRVIAPAETDKKDSE 436


>UniRef50_C8X404 CBS domain containing protein n=2 Tax=Desulfovibrionales
           RepID=C8X404_DESRD
          Length = 285

 Score =  297 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 96/274 (35%), Positives = 160/274 (58%), Gaps = 4/274 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           + +G    L+ + F G+    + +  +I ++  +  ++     ML  V+ +  ++VR+IM
Sbjct: 4   SPEGKLWTLVRKFFSGK--TENPIEDVILEARTDGELEAFEASMLINVLRMGRKQVREIM 61

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE-- 131
           IPR+ +  +++N ++ +  ++IIE  HSR PV  E+KDHI G++ AKDLLP++ +  E  
Sbjct: 62  IPRTDIQCVEQNASIQDVAELIIEHGHSRIPVYRENKDHIIGVVHAKDLLPYLLNHCETP 121

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  ++R    +PE+K V  M+ EF++Q+ HMAI +DE+GG SGLVT ED+LE IVGE
Sbjct: 122 PDPLSAIMRPPFFIPETKNVKNMIAEFQAQKVHMAIALDEYGGTSGLVTFEDVLEEIVGE 181

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           IEDEYD     D + +      V    S+ D  E  G   + ++V+TIGG V +  G +P
Sbjct: 182 IEDEYDLPRPEDIQVMEDGRHLVAGRTSLNDLEEETGVSLTSDQVETIGGFVTELAGRVP 241

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
             GE  D  G+ F++  ADS+++  V +    ++
Sbjct: 242 MTGEEFDYLGHNFRIEEADSKQVYAVSILPRVET 275


>UniRef50_C0CHP0 Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica
           DSM 10507 RepID=C0CHP0_9FIRM
          Length = 460

 Score =  297 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 76/292 (26%), Positives = 160/292 (54%), Gaps = 9/292 (3%)

Query: 9   SDTISNKKGFFSLLLSQLFH--GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           +  IS      + LL             +E+++++ ++ +  +I+E   +M++ ++  ++
Sbjct: 168 TSLISGISAGLTRLLGLDAKKVQGDVTEEEIISMVGEAHEQGVIEESEAEMIQNLISFSE 227

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
           +  +DIM PR  +  L    TL++ +++++E  +SR+PV  ED D+I G+L  +D++P +
Sbjct: 228 KEAKDIMTPRMNITALDAQMTLNDAIEIMLEEGYSRYPVYVEDLDNILGVLNFRDVVPII 287

Query: 127 RS-----DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
                  +     +  ++R  V +PE++ ++++L+  ++++ HM +V+DE+G   GLV +
Sbjct: 288 TKSERAGERPLRELPGLIRSVVFIPETRGINQILQGMQARKTHMVVVVDEYGQTEGLVAM 347

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGG 241
           EDILE IVGEI DEYD E++ + +     +  +     +E+  E  G  F D+E++T+ G
Sbjct: 348 EDILEEIVGEIHDEYD-EEEANIQPQLDQSVIIDGFTRLEELEEELGMEFGDQEMETLNG 406

Query: 242 LVMQAFGHLPARGE-TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            +     H+P   +  +  +GY+F++   ++  I +V  +    + Q  L+E
Sbjct: 407 YLTYMLDHIPTIKDKEVIANGYRFEILSVENNTIQKVKARKLPSAAQTPLEE 458


>UniRef50_C7RRT5 CBS domain containing protein n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RRT5_9PROT
          Length = 281

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 131/283 (46%), Positives = 187/283 (66%), Gaps = 4/283 (1%)

Query: 8   SSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
            S + S K GFF  L S L   EP++R++L+ L+  + Q  L+D D   + EG +  ++ 
Sbjct: 2   DSSSPSGKPGFFERLSSLLVR-EPEDREQLVQLLHAAHQRKLLDADALSITEGALAASEM 60

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
            VR++M+PR QM  +    TLD+ +D +  +AHSRFPVI+ D+DH+ GIL+AKDLL    
Sbjct: 61  IVREVMVPRPQMEVVDVGDTLDDVIDRVNTTAHSRFPVINGDRDHVVGILLAKDLLRV-- 118

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
                F++ + +R AV +PE KR+D +L+EFR  R HMAIVIDE+ G++GL+TIED+LE 
Sbjct: 119 RRDAPFNLREWVRPAVFIPEFKRLDVLLREFRVSRNHMAIVIDEYAGIAGLITIEDVLEQ 178

Query: 188 IVGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
           IVGEIEDEYD +E D + +      + V+A A++ DFN A GTHFSDE+ +T+GGLV+  
Sbjct: 179 IVGEIEDEYDFDEADENIQLDQNGLYRVKAHAAVADFNAALGTHFSDEKCNTVGGLVLHH 238

Query: 247 FGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            G +P   ETI IDG +F+V  ADSRRI  + V  P ++  P+
Sbjct: 239 LGRVPQFNETIVIDGTRFQVLRADSRRIYTLIVTRPPEADSPE 281


>UniRef50_C3MCE9 Putative uncharacterized protein n=1 Tax=Rhizobium sp. NGR234
           RepID=C3MCE9_RHISN
          Length = 431

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 68/271 (25%), Positives = 135/271 (49%), Gaps = 4/271 (1%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
             L+  +    +    +E+ A++    ++  I++   +ML  ++ + D+ V+ IM  R++
Sbjct: 162 MRLMGMKAEDADHVTEEEVHAIMASGVESGAIEKSEHEMLRRIIRLDDRNVKSIMTHRTE 221

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           +  +  N +L+     I +  HSR+PVI      + G ++AK++L    +    F + K 
Sbjct: 222 VSFIDVNDSLETIGRKIRQFGHSRYPVIDGPAGDVVGAVLAKEILNAPIA--APFDIRKY 279

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R+ + +PE+    + L+ F++   +MA+++DE+G   G++T  DILE IVG I   YD+
Sbjct: 280 VREILTLPETATCLKALEAFKASSVNMAMIVDEYGSTEGIITTADILEAIVGVIPSNYDD 339

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTH--FSDEEVDTIGGLVMQAFGHLPARGET 256
            +    R     ++ V     I++ +   G     +D + +TI G ++Q     P  G+ 
Sbjct: 340 IEHAHIRAREDGSYLVDGRTPIDEIHLQIGIEGIDNDGDFETIAGFLVQQLRKTPEEGDC 399

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            +  GY+F+V   D RRI ++ V    +   
Sbjct: 400 AEAHGYRFEVLDMDGRRIDKILVSRRAEEHS 430


>UniRef50_B8GI66 Putative uncharacterized protein n=1 Tax=Methanosphaerula palustris
           E1-9c RepID=B8GI66_METPE
          Length = 435

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 82/278 (29%), Positives = 134/278 (48%), Gaps = 6/278 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +     ++L ++   G P   +E+  LIR+  Q  +  E+ + M+  ++ ++D+RV  +M
Sbjct: 160 STDLVLAMLGAKNSSGSPVTEEEVKLLIREGTQAGVFLEEEQAMVSRILRLSDRRVSGLM 219

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR ++  +       E + ++  S HS FPVI  D D I G++  +DL   M    EA 
Sbjct: 220 TPRPEITAIDLRSPDLEQIALMRASGHSYFPVIDGDLDRIRGMVSVRDLWARMLDGQEA- 278

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           ++   L + + +PES    ++   FR    H+ +V DE+G V GLVT  DILE IVG + 
Sbjct: 279 TVRGALSEPLYIPESVPALKVPALFRDAGLHLGLVTDEYGSVQGLVTPHDILESIVGVLP 338

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT-HFSDEE---VDTIGGLVMQAFGH 249
              D+E + +  Q    +W V  +  ++ F +         EE     TIGGLVM     
Sbjct: 339 S-PDQEAEPEIVQRDDGSWLVDGMLPLDQFRDVVPLEDLPLEEKGYYHTIGGLVMMHLER 397

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            P  G+       QF+V   D  R+ +V V   D++ Q
Sbjct: 398 RPQTGDRFTHGDLQFEVVDMDGNRVDKVLVTQVDEADQ 435


>UniRef50_A5EY48 Transporter associated domain protein n=2 Tax=Cardiobacteriaceae
           RepID=A5EY48_DICNV
          Length = 288

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 131/292 (44%), Positives = 187/292 (64%), Gaps = 4/292 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M+D+ S S    S+     +LLL+     E   +D    L+ D   N  I++DT  M+E 
Sbjct: 1   MNDEFSGSK---SSWLKKLALLLTDKTQPEN-PQDAFHLLLDDYRHNQTINDDTATMMES 56

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           ++++    VRD+MIPR QM+ +  + +LD+ L VII+S HSR+PVI E  + I GIL+ K
Sbjct: 57  LLELNHTHVRDVMIPRGQMVVIHEHWSLDKVLSVIIQSGHSRYPVIDESHEKILGILITK 116

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLLP +  D E  +   V+R A VVPESK +D ML++FR+ R HMAIVIDE+G +SGLVT
Sbjct: 117 DLLPILVDDDENPNFMAVIRSATVVPESKPLDAMLRDFRTNRNHMAIVIDEYGNLSGLVT 176

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IED++E IVGEI+DE+D+  D + R L   ++ V+AL  IE FNE F TH  DE+ DTIG
Sbjct: 177 IEDVIEEIVGEIDDEHDQIPDAEIRTLPDGSYQVKALMMIEHFNEQFQTHLPDEDADTIG 236

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           G ++  FG +P  GE + IDG++  V+ A+ RRI+Q+ V   ++    K +E
Sbjct: 237 GYLLHYFGRIPINGERLSIDGWEIIVSKANQRRILQLKVVATNEEHTEKAEE 288


>UniRef50_C1ZED0 CBS domain-containing protein n=1 Tax=Planctomyces limnophilus DSM
           3776 RepID=C1ZED0_PLALI
          Length = 453

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 62/281 (22%), Positives = 128/281 (45%), Gaps = 5/281 (1%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
            K    +L  +    +  + +++  LI    +  ++ E  + M +  + + ++   +I+ 
Sbjct: 165 TKSVLLILGQKTEIRDSVSVEDIQHLIDAGHEAGILHEAEQQMAQQALKMRERTAAEILR 224

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR  +  +  +   +E L  +  S  SR PV     D I G +  KD+         +  
Sbjct: 225 PRIDIDAIDVDTPPEEVLGAMAMSGFSRVPVCEGSIDRIVGFIYIKDVFLENYLGR-SLD 283

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           + +V+R  + +P++  + ++L+ F+ +R  +AIV+DE+GG  G+VT+ED++E++VG I D
Sbjct: 284 IRRVMRAPLFIPKTLTISKLLELFQKERTQLAIVLDEYGGTEGMVTLEDVMEILVGSIHD 343

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT----HFSDEEVDTIGGLVMQAFGHL 250
           E+  +D+    + +  +    A  ++ +  EA             + TI GLV+      
Sbjct: 344 EHRRDDEQLIVRRADGSLLADAALNLHELQEALEFSKWPEPPPRGIATISGLVVALLKRP 403

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           P  G+ I     + +V   D  RI ++ V         + +
Sbjct: 404 PKIGDIIQWSQLRVEVVDMDGPRIDRLLVSRIVPESSNEAE 444


>UniRef50_C4V614 TlyC family hemolysin n=14 Tax=cellular organisms
           RepID=C4V614_9FIRM
          Length = 447

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 85/257 (33%), Positives = 142/257 (55%), Gaps = 2/257 (0%)

Query: 25  QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKR 84
           +  + +    +E+  L+++S +  LI+    D ++ V    +   R+IM+PR+ MI L  
Sbjct: 176 KGENEDAHTEEEIRLLMKESYRQGLINSTEADFVDKVFSFTELNAREIMVPRTDMICLYL 235

Query: 85  NQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVV 144
           + +  E +  I+E   +R+PV  EDKDHI G +  KDLL  +    E  ++ + +R+A++
Sbjct: 236 DDSPAERIKTILEEQQTRYPVCYEDKDHIIGFIHVKDLLAPLMRG-EQLNLRRYIRKALI 294

Query: 145 VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF 204
           VPES     +L+  + Q Y +AIV+DE+GG +G+VT+EDI+E IVG+I DE+D E +   
Sbjct: 295 VPESMDGSILLRTMQEQGYQLAIVVDEYGGTAGMVTVEDIIEQIVGDIRDEFDVERES-V 353

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQF 264
                   ++ A   +E+ N+  G    DE+VD+IGG +    G  P  G+    +G   
Sbjct: 354 EWRDLDICSIDAKLLLEEVNDLLGIRIEDEDVDSIGGWLYDQLGEAPRVGQMAAHEGALL 413

Query: 265 KVAMADSRRIIQVHVKI 281
            V   D  RI +V V++
Sbjct: 414 YVEEVDGIRITRVLVRL 430


>UniRef50_C6QET7 Putative uncharacterized protein n=1 Tax=Hyphomicrobium
           denitrificans ATCC 51888 RepID=C6QET7_9RHIZ
          Length = 441

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 77/249 (30%), Positives = 128/249 (51%), Gaps = 4/249 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+   I    +   + +   +ML G++D+ D +V DIM+ R++M T+  +    + LD 
Sbjct: 169 EEIRGTIDLQAKEGTVAKGDAEMLGGILDLGDLQVADIMVHRTKMETVNADDPPAKILDQ 228

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS---DAEAFSMDKVLRQAVVVPESKRV 151
           +++S  +R P+  E+ ++I G+L  KDLL  +       E   + K       VP++  +
Sbjct: 229 LMKSQFTRVPIWKEEPENIVGVLHTKDLLLALSRTGWAPETLDIMKSASTPWFVPDTTTL 288

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
              L +F  ++  MA+V+DE+G V GL+T+EDILE IVG+I DE+D   D   R  S  T
Sbjct: 289 KDQLNQFLKKKTQMALVVDEYGEVQGLITLEDILEEIVGQITDEHDNP-DSHIRMQSDGT 347

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
             V    +I D N        D+E  TI GLV+     +P  G+     GY+F++     
Sbjct: 348 VNVDGTVAIRDLNRHLDWDLPDDEATTIAGLVIHEAQTIPEPGQVFTFHGYRFEILRKSR 407

Query: 272 RRIIQVHVK 280
            +I  + +K
Sbjct: 408 NKITAIRIK 416


>UniRef50_D1VUR6 CBS/transporter domain protein n=1 Tax=Peptoniphilus lacrimalis
           315-B RepID=D1VUR6_9FIRM
          Length = 439

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 91/283 (32%), Positives = 154/283 (54%), Gaps = 8/283 (2%)

Query: 10  DTISNKKGFFSLLLSQLFH--GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
             +S        LL +      E  + +EL + I+ S +  +I+    DM+  +MD  D+
Sbjct: 157 KLLSISTVLVLKLLGKYSEDVEEQISEEELKSYIKVSQEQGVINSTGEDMIINIMDFDDK 216

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
              +IM PR+ +  +  ++   + +  I+ + +SR PV  E+ D+I GI+  KDL     
Sbjct: 217 MAYEIMTPRTAIFMVDYDEFSVDSISEILATGYSRMPVYRENADNIIGIINIKDLFIEYE 276

Query: 128 SDA-EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
            +  + F++DK L+    VPE+K++DR+LKE ++ + ++AI+IDE+GG SG+VT+EDI+E
Sbjct: 277 KNNYKNFNLDKCLKTPYFVPETKKIDRLLKELQTSKNYVAILIDEYGGFSGMVTVEDIVE 336

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            IVGEIEDEYD        ++  + + V    +IED NE   T    E  +TI GL+++ 
Sbjct: 337 EIVGEIEDEYDRNTPS-MEKIGPNEYMVDGYMTIEDINEELDTKLFSENHETISGLIIEK 395

Query: 247 FGHLPARGET----IDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            G++P   E     +  +G    V     +RI++  +KI D+ 
Sbjct: 396 LGYIPEENEKKKLQVKTNGVMLTVLAIKDKRIVKAALKILDNK 438


>UniRef50_Q310P2 CBS n=6 Tax=Desulfovibrionaceae RepID=Q310P2_DESDG
          Length = 298

 Score =  297 bits (761), Expect = 4e-79,   Method: Composition-based stats.
 Identities = 92/270 (34%), Positives = 156/270 (57%), Gaps = 3/270 (1%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
                  L S+ F  +  N D +   I ++  +  +D +   ML  ++ + + +V +IM 
Sbjct: 31  SDSRLWSLFSRFFSAK--NGDSVEQAIIEAQDDGELDSEESTMLLSILRLDEMQVYEIMT 88

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS-DAEAF 133
           PR+ +       +L + +D+I+ S HSR PV  +++D+I G++ AKDLL  +      + 
Sbjct: 89  PRTDIDCADDQSSLGDIIDLIVSSGHSRIPVYRDNRDNIIGVVYAKDLLSVLTDTGQRSA 148

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + + +RQ + VPE+K+V  +L+EFR+++ H+AI +DE+GG SGLVTIED+LE+IVG+IE
Sbjct: 149 PVTETMRQPIFVPETKKVSELLQEFRTRKNHLAIALDEYGGTSGLVTIEDVLEVIVGDIE 208

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DE+D     D R L   T  V   A +ED +E  G     ++V+TIGG + +  GH+P  
Sbjct: 209 DEHDAPRQEDIRALDDGTLEVSGRAFLEDLSERLGVLLESDQVETIGGYLSEIAGHVPQA 268

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           GE+  +  + + V  AD+++I  + V   +
Sbjct: 269 GESFTVGAHSYTVMEADAKQIKTIRVTPSE 298


>UniRef50_B9Y7L5 Putative uncharacterized protein n=1 Tax=Holdemania filiformis DSM
           12042 RepID=B9Y7L5_9FIRM
          Length = 399

 Score =  297 bits (761), Expect = 4e-79,   Method: Composition-based stats.
 Identities = 73/284 (25%), Positives = 143/284 (50%), Gaps = 7/284 (2%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
             S  K   S++  ++ + +   ++ELL ++ ++     ++    D++   ++  D  V+
Sbjct: 107 LFSLWKKLLSMMF-KVENDDSMTQEELLTIVEEAQNEGDLEAHESDLICAAIEFNDLDVK 165

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           DI+ PR  +I +    +LDE   +   +  SR PV     D+I G++  KD      +  
Sbjct: 166 DILTPRVDVIAVDVTDSLDEIELMFRNNNFSRLPVYENSIDNIVGVIHEKDFYNLYYNHM 225

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
             F    + +  +      ++  +LK+ +S + HMA+V+DE+GG +G++T+EDILE +VG
Sbjct: 226 GTF--KSITQTLLYTSPHVKISSLLKQLQSSKTHMAVVLDEYGGTAGIITLEDILEELVG 283

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD--TIGGLVMQAFG 248
           EI DE+D+  +  +++L  +T+ +     ++D  E FG    +E+ D  T+ G V+    
Sbjct: 284 EIYDEHDQVKE-YYKELDPNTYLIECDMDLDDMFEFFGLE-DEEDYDFITVSGWVIHELE 341

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            +P  GE+         V   D+R++I+V V +       + D+
Sbjct: 342 RIPKVGESFTYKNLVVTVTQTDARKVIEVKVSVIPQDQSEEDDD 385


>UniRef50_Q2FN37 Putative uncharacterized protein n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FN37_METHJ
          Length = 437

 Score =  297 bits (761), Expect = 4e-79,   Method: Composition-based stats.
 Identities = 69/286 (24%), Positives = 142/286 (49%), Gaps = 10/286 (3%)

Query: 10  DTISNKKGFFSLLLSQLFHGEPKN-----RDELLALIRDSGQNDLIDEDTRDMLEGVMDI 64
              S      + ++ +LF   P        +E+  L+ +  ++ +IDE  +DM+E V + 
Sbjct: 151 SPFSYLTSGLTNIIVKLFGISPVTSPDVIEEEIHMLLEEGTESGIIDETEQDMVESVFEF 210

Query: 65  ADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP 124
            D ++ D+MIPR  ++ L  N  + +  ++I  + H+R+P+  +  D I GI+  +DL  
Sbjct: 211 GDSQIADLMIPRPDIVALNLNDPITKNFEIIERTGHTRYPIYQDTLDSIIGIISIRDLW- 269

Query: 125 FMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDI 184
            +          K+++  +VVP++ +   +++ F++    +A++IDE+G V GL+T+ D+
Sbjct: 270 LIAHKNTEVDFSKIMQDILVVPDNMKALDLIRRFKTATSPLAVIIDEYGSVVGLITLHDL 329

Query: 185 LELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE----VDTIG 240
           LE +VG++     ++++    +    +W +    S E+  E  G   S+E       T+ 
Sbjct: 330 LEALVGDLSRVDQDDEEPLITRRHDGSWLIDGRTSPEELYEITGIDCSEESSKGAFRTMA 389

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
           G ++   G +PA G+    DG +++V   D  RI ++ +       
Sbjct: 390 GFILYKMGSIPATGDYFSYDGNEYEVVDMDGHRIDKILITRLPSPE 435


>UniRef50_Q30WW6 CBS n=5 Tax=Proteobacteria RepID=Q30WW6_DESDG
          Length = 442

 Score =  297 bits (761), Expect = 4e-79,   Method: Composition-based stats.
 Identities = 77/283 (27%), Positives = 135/283 (47%), Gaps = 8/283 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      L+            +++ A++ +  Q  +I++   DM+  V  + D+++  +M
Sbjct: 156 STDALLRLVGKTELSSANLTEEDIHAILTEGSQAGVIEKHEHDMVRNVFRLDDRQIPSLM 215

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PRS ++ L   Q LD  LD ++ S HSRFPV       + G++ AK LL     +  A 
Sbjct: 216 TPRSDIVFLDITQPLDGFLDTVVASDHSRFPVCRGGLHEVLGVISAKRLLKQRLKNEPAE 275

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            +   L  AV VPES    ++L++FR     M  V+DE+G +SGL+T++D+LE + G+  
Sbjct: 276 KLTGYLLPAVYVPESLTGMKLLEQFRESGVQMVFVVDEYGDISGLITLQDLLEALTGKFR 335

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFGH 249
               + D++   Q    +W +  L  + +  +        DE      T+ G++M  FG 
Sbjct: 336 --PRDPDEMWAVQRDDGSWLLDGLIPVPELKDRLDLKTVPDEAKVRYHTLSGMMMWLFGR 393

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD--DSPQPKL 290
           LP  G+  +  G+Q +V   D +RI +V        ++ QP  
Sbjct: 394 LPRTGDVAEWQGWQLEVVDLDGKRIDKVLASRISGYEASQPSA 436


>UniRef50_Q1IKR7 Putative uncharacterized protein n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IKR7_ACIBL
          Length = 455

 Score =  296 bits (760), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 83/289 (28%), Positives = 150/289 (51%), Gaps = 17/289 (5%)

Query: 15  KKGFFSLLLSQ-LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
            +    L  ++ +  G   + +EL  ++  S +  L+     +M+   +D+ +  VR+IM
Sbjct: 163 ARFVLRLFGTKEMREGGVHSPEELKLMVTASRKFGLVPRLQEEMINRAIDLENISVREIM 222

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVI--SEDKDHIEGILMAKDLLPFMRSD-- 129
           +PR  + +L  + TLDE +  +++  HSR P+       +HI G+L AKDL+ +MR    
Sbjct: 223 VPRPDIFSLPGHMTLDEAVQRVVDEQHSRIPIYDAERGPEHIIGVLYAKDLMRWMRYRIA 282

Query: 130 ----------AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
                     A    +  ++R+ +VVPE+K +  +L+EF+ ++ H+A+V+DEFG  +G+V
Sbjct: 283 RLQQNRPARIASNLKVQHIMREVLVVPETKPLTDLLEEFKERKRHLAVVVDEFGSTAGVV 342

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDT 238
           T+ED+LE +VGEIEDE+D  ++         T  +    +I D    +      DE  +T
Sbjct: 343 TVEDVLEELVGEIEDEHDVPEESALTP-GGTTLVLDGGINIRDLESQYQVRLPRDEGFET 401

Query: 239 IGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           + G VM     +P  G++     Y+F V   + RRI  V +++   + +
Sbjct: 402 LAGFVMTRLQRIPREGDSFAFHNYRFTVLEMEGRRIDSVKLELIQQAEE 450


>UniRef50_Q67QV0 Putative hemolysin n=1 Tax=Symbiobacterium thermophilum
           RepID=Q67QV0_SYMTH
          Length = 452

 Score =  296 bits (760), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 78/282 (27%), Positives = 133/282 (47%), Gaps = 12/282 (4%)

Query: 13  SNKKGFFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           ++      LL  Q    EP  + +EL   +    +N  + E  + M+ GV    D+ VR 
Sbjct: 159 ASTNLVVRLLGGQAQPAEPGISEEELRLYV---AENTGLQEAEKRMIAGVFSFGDRSVRQ 215

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M+PR++M  L ++  L E L  +      R+PV  ED D I G++  KDLL      A 
Sbjct: 216 VMVPRTEMACLHQDAPLPEALAEVRRHGFWRYPVYREDYDDIVGMVTVKDLLRHADPQAG 275

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
             ++  V+R A  VPESK+   +LKE ++    +A+V+DE+GGVSGLVT+ED+L      
Sbjct: 276 LRTVADVMRPAWFVPESKQALSLLKEMQAADEQLAVVVDEYGGVSGLVTMEDLL------ 329

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHL 250
            E   +  ++            +     +++  E            +T+ G ++   G +
Sbjct: 330 EEIIGEIAEEPSPPSAEPRELELDGGEPVDEVAEQLHIPIPRSPHYETLAGYILHHLGAI 389

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           P+ G+ + + G++ +V   D  RI +V   +PD    P   +
Sbjct: 390 PSEGDELAVSGWRLRVVRMDGHRIDRVRA-VPDAPDAPGASD 430


>UniRef50_C8P0P9 CBS domain protein n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414
           RepID=C8P0P9_ERYRH
          Length = 442

 Score =  296 bits (760), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 75/288 (26%), Positives = 148/288 (51%), Gaps = 13/288 (4%)

Query: 14  NKKGFFSLLLSQLFHGE-PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +      ++       E     +E+  ++        ID   ++M+  + +  +  V DI
Sbjct: 159 STNLVLRIIGIDPDKAEDEVTEEEIRIMVD----AGEIDVTEKEMINNIFEFDNLDVADI 214

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM--RSDA 130
           M  R++++ +  + +  + ++++ E  ++R+PV  +  D+I G++  +DLL ++    D 
Sbjct: 215 MTHRTEVVGIDVSSSFADIMELVDEERYTRYPVYEDSIDNIIGLIHLRDLLRYVKDHRDD 274

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           E F + K++R+   VP+SKR D + +E ++ + H A+VIDE+GG +G+VT+ED++E I+G
Sbjct: 275 EVFEIKKIIREPYYVPDSKRTDELFRELQNSKMHFAVVIDEYGGTAGIVTMEDLIEEIMG 334

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
            I DEYDEE++ +   ++   + V     IED  +    +   E+ DT+ G V+   G L
Sbjct: 335 NIMDEYDEEEEQEIVAVNLDEYLVDGACDIEDLEDVININLPVEDYDTVSGFVVGQIGRL 394

Query: 251 PARGET------IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           P   +       +   GY+F +   D + I +V V    +     L++
Sbjct: 395 PTEEDVREDLSDVIYHGYRFSIMELDEKVIARVRVTKEKEVDLDSLED 442


>UniRef50_C0EHV3 Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum
           DSM 5476 RepID=C0EHV3_9CLOT
          Length = 428

 Score =  296 bits (759), Expect = 7e-79,   Method: Composition-based stats.
 Identities = 71/282 (25%), Positives = 137/282 (48%), Gaps = 3/282 (1%)

Query: 12  ISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           + N     +   ++          EL  ++ +     ++++    ++   +D  +    +
Sbjct: 148 LFNGLKKLTERFTKSDSQPSVTEQELKVIVEEIESEGVLEDHESQLVRSALDFDETTAEE 207

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +++PR  +++++ N +++E   + +    SR PV     D+I G+L  KD       + E
Sbjct: 208 VLVPRVDIVSVEVNASVEEMKQLFLTERFSRVPVYERSIDNIVGVLYEKDFFRSYIQNGE 267

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  +L+Q + +P   ++  +LK+ +S R HMA+V D++GGV G+VT+ED+LE +VGE
Sbjct: 268 NIDIRGLLQQPLFIPPQTKISDLLKQIQSVRAHMAVVTDQYGGVEGIVTLEDVLEELVGE 327

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS--DEEVDTIGGLVMQAFGH 249
           I DE DEE   D ++L    + V    ++ED  E  G        + +T+GG V +   H
Sbjct: 328 IYDE-DEEIVEDVQRLGSGLYRVNPDMAVEDLFEEIGFEPKNFSSDSNTVGGWVFELLEH 386

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           +P  GE +  +     V     +RI  + V + + S   + D
Sbjct: 387 IPEPGEQVSFEELTLTVTDLSDQRIRSLEVHLGESSDPEQQD 428


>UniRef50_Q9CM13 Magnesium and cobalt efflux protein corC n=264
           Tax=Gammaproteobacteria RepID=CORC_PASMU
          Length = 300

 Score =  296 bits (758), Expect = 7e-79,   Method: Composition-based stats.
 Identities = 182/292 (62%), Positives = 232/292 (79%), Gaps = 2/292 (0%)

Query: 3   DDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVM 62
           + ++  S     KK FF  L  + F GE KNR+EL+ +IRDS QN+LID++TR+M+EGVM
Sbjct: 5   EQSNTYSTESHQKKSFFQSLFGRFFQGELKNREELVEVIRDSEQNELIDQNTREMIEGVM 64

Query: 63  DIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL 122
           +IA+ RVRDIMIPRSQ++ +  +Q LD CLD II SAHSRFPVI++++D+I GIL AKDL
Sbjct: 65  EIAELRVRDIMIPRSQIVFIHTDQNLDSCLDTIIVSAHSRFPVITDERDNIAGILHAKDL 124

Query: 123 LPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIE 182
           L F+RS+AE F +  +LR AV+VPESKRVDRMLK+FRS+R+HMAIV+DEFG VSGLVTIE
Sbjct: 125 LRFLRSNAEEFDLMPLLRPAVIVPESKRVDRMLKDFRSERFHMAIVVDEFGAVSGLVTIE 184

Query: 183 DILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGL 242
           DILE IVG+IEDE+DEE+ ++ RQLSRHT+ VRAL  IEDFN+ F THF+DEEVDTIGG+
Sbjct: 185 DILEQIVGDIEDEFDEEEIVNIRQLSRHTYAVRALTDIEDFNQQFNTHFADEEVDTIGGV 244

Query: 243 VMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD--SPQPKLDE 292
           VMQAFG+LP RGE I I+   FKV  ADSRR+IQ+ + + D+  +   K +E
Sbjct: 245 VMQAFGYLPKRGEEITIENIGFKVTSADSRRLIQLRITVTDEQLAEIEKAEE 296


>UniRef50_A2SSZ1 Putative uncharacterized protein n=1 Tax=Methanocorpusculum
           labreanum Z RepID=A2SSZ1_METLZ
          Length = 420

 Score =  296 bits (758), Expect = 9e-79,   Method: Composition-based stats.
 Identities = 87/275 (31%), Positives = 139/275 (50%), Gaps = 8/275 (2%)

Query: 22  LLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMIT 81
              +  H      +E+   I        I+E+ ++M+  V+   D   ++IM PR  +  
Sbjct: 144 RFRKKDHSPSVTEEEIREWIDVGEMEGAIEEEEKEMIYSVLKFNDTTAKEIMTPRPDVAV 203

Query: 82  LKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQ 141
           ++   TL+E +    E+  SR PV  +  D+I G L  KDL     +D    S+  ++  
Sbjct: 204 VEDTVTLEEAVSHFRETGFSRVPVYHDKTDNIVGTLNFKDLFNAYSTDNRKASVKSLMLD 263

Query: 142 AVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDD 201
              VPESK++D +L+E + +R HMAIV+DEFGG SG+VT EDILE +VG+I DE D ++ 
Sbjct: 264 VYCVPESKKIDVLLRELQVRRVHMAIVLDEFGGFSGVVTFEDILEELVGDIMDESDGDEV 323

Query: 202 IDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE--VDTIGGLVMQAFGHLPARGETIDI 259
            D   +    + + A   +   NE F     ++    +TIGGLV    GH+P  GE+I +
Sbjct: 324 SDIIPIGDGLYMIDAQVRVALLNERFDISLPEDPGNYETIGGLVFSQLGHIPRLGESIPL 383

Query: 260 DG--YQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            G      V     R+I++V + +      P+ D+
Sbjct: 384 PGDHITLVVTKMRGRQILKVKMIL----AAPEYDD 414


>UniRef50_Q164J1 CBS domain protein n=37 Tax=Rhodobacterales RepID=Q164J1_ROSDO
          Length = 435

 Score =  296 bits (758), Expect = 9e-79,   Method: Composition-based stats.
 Identities = 76/277 (27%), Positives = 138/277 (49%), Gaps = 12/277 (4%)

Query: 16  KGFFSLLLSQLFHGEPK--NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +G   L    +           E+   +       +++++ RD + G +D+ ++ V +IM
Sbjct: 157 RGVLRLFGVTIDPDSNILDVHAEIEGALTLGHSEGVVEKEHRDRILGALDLNERAVEEIM 216

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS----- 128
           + RS +  +  +    + L   ++S H+R PV  E  ++I G++ AKDLL  M       
Sbjct: 217 LHRSGIEMINADDDPQDILHQCLQSNHTRLPVFQEHPENIIGVIHAKDLLRAMYKIIGGP 276

Query: 129 -----DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIED 183
                   +F +  V  +   VPE+  +D  +++F  +R H A+V+DE+G + GL+T+ED
Sbjct: 277 EGDASKLRSFKLSDVAMKPYFVPETSTLDEQMRQFLRRRTHFALVVDEYGSLQGLITLED 336

Query: 184 ILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLV 243
           ILE IVGEI DE+D  D    +Q     + +    +I D N A   +  D+E +T+ GLV
Sbjct: 337 ILEEIVGEITDEHDPTDMAPIQQTEDGQFVIDGAMTIRDLNRAADWNLPDDEANTVAGLV 396

Query: 244 MQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
           +     +P  G+     G++F+V   +  RI ++ ++
Sbjct: 397 IHEAQMIPTTGQVFSFHGFRFEVCAREGNRITELKIR 433


>UniRef50_A8SE58 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=A8SE58_9FIRM
          Length = 434

 Score =  296 bits (758), Expect = 9e-79,   Method: Composition-based stats.
 Identities = 75/278 (26%), Positives = 142/278 (51%), Gaps = 7/278 (2%)

Query: 19  FSLLLSQLFH---GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           +   L    H    +     EL+ ++ ++  +  + +   +++   ++  D  V +I+ P
Sbjct: 149 WKRFLGHFVHSTEEDTITEGELMTMVSEAENDGELTDRESELIRSAIEFDDVEVEEILTP 208

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  +I ++ +  L+E      ES +SR PV  +  D+I G++  KD   +M    +   +
Sbjct: 209 RVDVIAVEDDMPLEEVAQTFAESGYSRLPVYHDTIDNIIGVVHEKDF--YMARLKKETKL 266

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
           + +++  +    S ++ ++L+  R Q +HMA+V+DE+GG  G++T+EDILE +VGEI DE
Sbjct: 267 EDLVKPTLYTTGSTQISQLLRTLREQHHHMAVVVDEYGGTEGIITLEDILEELVGEIWDE 326

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARG 254
           +DE  + DFR+ S  +W V   A ++D  E  G    ++ + +T+ GLV +    LP  G
Sbjct: 327 HDEVTE-DFRKQSDGSWIVLGSAGVDDLYERLGLPEDEDIDSNTVNGLVQEKTCRLPKVG 385

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           +   +  Y   V     RR+ +V +   +     K +E
Sbjct: 386 DRFTLGSYDGVVTRTAKRRVTEVRLTPAEKPDTKKDEE 423


>UniRef50_Q7NMI1 Glr0785 protein n=2 Tax=Bacteria RepID=Q7NMI1_GLOVI
          Length = 477

 Score =  296 bits (758), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 79/289 (27%), Positives = 141/289 (48%), Gaps = 13/289 (4%)

Query: 14  NKKGFFSLLLSQLF--------HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIA 65
           +   + S L+ + F        H  P   +EL  LI  S  +  +D+  +++LE V +  
Sbjct: 177 SFLNWSSWLVLRAFGVKANVNTHTNPIGPEELQLLISSSSASG-LDKGEQELLENVFEFG 235

Query: 66  DQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF 125
           D    D+M+PR+ +  L    T+ E L  +  + HSR+P+  +  D I+G +  KD++  
Sbjct: 236 DAVAIDVMVPRTSIDALPFTATIQEVLFEVSRTGHSRYPLYEDSLDTIKGQVSIKDVITP 295

Query: 126 MRSDA--EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIED 183
           +         ++  + R  + VPE+KR+  +L + + +R  M IV+DEFGG +GL+T+E+
Sbjct: 296 LAKGEVQPTDTVGGLARPILFVPENKRISELLTQMQRERQAMVIVVDEFGGTAGLLTMEN 355

Query: 184 ILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGL 242
           +LE +VG I DE D+    D  +L   T  ++A  ++E+ N+         +E  T+GG 
Sbjct: 356 LLEELVGNITDESDQAT-PDIVKLDERTAIIQAQINLEELNDFLDLQLPISDEYKTLGGF 414

Query: 243 VMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           VM     +P  GE    +  +F V   +  R+ +V +           +
Sbjct: 415 VMYQLHKVPEAGEQFFYNELEFTVLEMEGPRLERVRLVWRTREEVEAAE 463


>UniRef50_A0LG68 CBS domain containing protein n=1 Tax=Syntrophobacter fumaroxidans
           MPOB RepID=A0LG68_SYNFM
          Length = 276

 Score =  295 bits (757), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 80/265 (30%), Positives = 144/265 (54%), Gaps = 4/265 (1%)

Query: 21  LLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI 80
             LS++   E     E+  LI +  Q  LI ED  +M++G+    D   R+IM+PR+  +
Sbjct: 4   RRLSRIGSSENI-EKEIQQLIDEGEQAGLISEDEGEMIQGIFSFRDTIAREIMVPRTDAV 62

Query: 81  TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLR 140
             +   T  + + +II+S HSR P+  +  D+I G L AKDLL +    ++   +  ++R
Sbjct: 63  YARAETTTADVIQLIIQSGHSRIPIYQDSIDNIIGTLHAKDLLKYW--GSDDVDLRAIIR 120

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
               +PESK++  +L++ R  + HMAIV+DE+GG +G++T+EDI+E I+G++ DEYD  D
Sbjct: 121 SPYFIPESKKISEVLEDLRDNKSHMAIVVDEYGGTAGILTLEDIIEEIIGDVMDEYD-AD 179

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
                +    + TV A   +E+  +       + + +++GG V+   G +P   E I  +
Sbjct: 180 VKLIVEHDDGSITVHARLDVEELEDFLDVKLPEGKFESVGGFVISLVGRVPGVNERIVFE 239

Query: 261 GYQFKVAMADSRRIIQVHVKIPDDS 285
             +  +  A +R+I ++ ++  D  
Sbjct: 240 NMEMVIEAASNRKIEKIRIRRVDPE 264


>UniRef50_A0LRV3 Putative uncharacterized protein n=1 Tax=Acidothermus
           cellulolyticus 11B RepID=A0LRV3_ACIC1
          Length = 438

 Score =  295 bits (757), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 77/274 (28%), Positives = 135/274 (49%), Gaps = 8/274 (2%)

Query: 15  KKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
                 LL        E  + +EL  L+           D R +++ V    D+R+R+++
Sbjct: 161 TNAIVRLLGGDPKAARESMSEEELRGLVTSHEALG---RDERQLIDEVFTAGDRRLREVL 217

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-EA 132
           +PR+++  L     + + L  +  + HSR+PV     D I G++  +DLL     +    
Sbjct: 218 VPRTEVEFLDATMPVGQALAQLRSTMHSRYPVFRGSHDEIIGMVHVRDLLAAQAENRGRT 277

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +  ++R   ++P+   V + L E R + + +A+V+DE+GG +G+VT+ED++E I+GEI
Sbjct: 278 VRVGDLVRPVKLLPDGLGVLQALSEMRREGHRLAVVVDEYGGTAGIVTLEDLVEEIIGEI 337

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DE+  +        +     V  L   EDF E  G    D   +T+ G ++ A GH+P 
Sbjct: 338 RDEHAPD---GVDASASGEMIVDGLTHTEDFAEETGIRLPDGPYETVAGFMLAALGHIPG 394

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
            GE +D+DGY+F VA  D RR+ ++ +       
Sbjct: 395 LGEWVDVDGYRFTVAELDGRRVAKIKITRRPTEA 428


>UniRef50_C7HS55 Transporter n=3 Tax=Anaerococcus RepID=C7HS55_9FIRM
          Length = 406

 Score =  295 bits (757), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 80/266 (30%), Positives = 135/266 (50%), Gaps = 2/266 (0%)

Query: 20  SLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQM 79
             L     + +    ++L  ++    +  +I+ +  +++  V D A     DIM PR+ M
Sbjct: 143 KKLSDGADNSDKVTEEDLKTIVDVGEEQGVINNEESEIINNVFDFAGSFASDIMTPRTNM 202

Query: 80  ITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVL 139
             +  + T +E    +IES HSR PV  E  D+I G+L  KD++ F+    E   +  +L
Sbjct: 203 EAIAIDSTKEELDKFLIESKHSRIPVYGESIDNIVGVLHMKDIVTFVAEGREP-RLKDML 261

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
           RQ     E+  +  + K  +     +AIV+DE+GG  GLV+IEDI+E +VG+I DEYD +
Sbjct: 262 RQTYYAYENMNIIDLFKSMKKMNVSLAIVVDEYGGTEGLVSIEDIIEELVGDIYDEYDPD 321

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
           D+    ++S + + V A   I DFN+ F     + + D++GGLV+     LP  G+ + +
Sbjct: 322 DEK-VYKVSDNEFIVDASMHINDFNDYFNRDIKEVKNDSVGGLVIDYLNRLPKTGDIVKV 380

Query: 260 DGYQFKVAMADSRRIIQVHVKIPDDS 285
           D         +  +I  + VK   +S
Sbjct: 381 DDVTLICEKVERYKINLLRVKFDSES 406


>UniRef50_C0FYH2 Putative uncharacterized protein n=1 Tax=Roseburia inulinivorans
           DSM 16841 RepID=C0FYH2_9FIRM
          Length = 316

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 72/283 (25%), Positives = 145/283 (51%), Gaps = 11/283 (3%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M D  S ++           L        +    +E+++++ +  +  ++  +  +M+  
Sbjct: 25  MDDGGSPTTGMKKLSNRLMKLFGVDT---DDVTEEEIISMVNEGHEQGVLQANEAEMIHN 81

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           + +  D+  +DIM+ R  +I +    T  E LD  IE+ +SR+PV  +D D+I G+L  K
Sbjct: 82  IFEFGDKDAKDIMVHRKNIIAIDGTMTFLEMLDFTIENNYSRYPVYIDDIDNIIGVLHIK 141

Query: 121 DLLPFMRSDA----EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           ++L   +           +  ++R+   +PE++ ++ +    ++ + HM IV+DE+G  S
Sbjct: 142 EVLALCQKQEIYHTAIKDIKGLIREVDFIPETRNINTLFTMMQNAKTHMVIVVDEYGQTS 201

Query: 177 GLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE- 235
           G+V +EDILE IVG IEDE+D+E+ +   +L   ++ +  + S E+  E    H  +E+ 
Sbjct: 202 GIVAMEDILEEIVGNIEDEHDQEEKM-IEKLPDGSYLMDGMTSAEEALEILKIHIPEEDE 260

Query: 236 VDTIGGLVMQAFGHLPARGETIDID--GYQFKVAMADSRRIIQ 276
            +T+ G+++     +P   E  + D  GY F+V   +++ I +
Sbjct: 261 FETLNGILISLLDRIPNDDEKFETDAFGYHFEVLQVENKMIKK 303


>UniRef50_C9LMB7 Putative transporter n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LMB7_9FIRM
          Length = 436

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 77/264 (29%), Positives = 139/264 (52%), Gaps = 5/264 (1%)

Query: 31  PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDE 90
               DE+  ++ +S +   ++     +++   D  D  VRD+MIPR+ M+ L  N  +D 
Sbjct: 176 TYTEDEIRCIVEESHRGGRLNTLENTLIKNSFDFFDLDVRDVMIPRNDMVVLDFNDDMDV 235

Query: 91  CLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKR 150
               I ++ H+ +PV  EDKDHI G +  KD L  +      +++ +++R+ + VPE   
Sbjct: 236 MRRNISKTHHTCYPVCMEDKDHILGFIHVKDFLESLLRGE--YNIKRIMREILTVPEVMP 293

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRH 210
              +L+  +++R ++A+V+DE+GG SGLVT+ED++E + GEI    +     +  +++ H
Sbjct: 294 APALLQMMKNKRTYLAVVVDEYGGTSGLVTLEDLMEELAGEIPQN-ESNAPAEILRVNDH 352

Query: 211 TWTVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
            +       +ED +E     F DEE  +TIGGL+      +P  G+ I   G++F V   
Sbjct: 353 VYEFDGTVILEDVSERLQMEFDDEERNNTIGGLIFSKLERIPQVGDHISFGGWKFTVLKM 412

Query: 270 DSRRIIQVHVKI-PDDSPQPKLDE 292
              RI++V  ++   +  +P   E
Sbjct: 413 YGFRIMRVKAEMDRKEETEPDSHE 436


>UniRef50_B8J8L5 CBS domain containing protein n=4 Tax=Anaeromyxobacter
           RepID=B8J8L5_ANAD2
          Length = 425

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 86/276 (31%), Positives = 150/276 (54%), Gaps = 3/276 (1%)

Query: 10  DTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
             ++    + +   ++     P   +   AL   +G+     E TR+++  V +  ++  
Sbjct: 148 RPLARAVAWSAGRRARFSLPPPPLDEMERALAEYAGRGGSGSEGTRELIHNVFEFREKVA 207

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           RD+M+PR+ ++ ++    + + +  + E  HSR PV  E  D I G+L A+DL+P +   
Sbjct: 208 RDVMVPRTDVVAVELGTPVPQIIRTLSEEGHSRMPVYRESLDQIAGVLHARDLVPLLAH- 266

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            E   +  +LR A  VP SK V+++L+E + +  HMA V+DEFGGV G+ TIED+LE IV
Sbjct: 267 PELIVLADILRPAHFVPWSKPVEQLLREMQRRHLHMAFVVDEFGGVMGICTIEDVLEQIV 326

Query: 190 GEIED-EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAF 247
           G+I+D   +E++  +  Q +  ++TV+  A++ +FN A      ++   +T+ G V    
Sbjct: 327 GDIQDEFEEEDEGREVEQHADGSFTVQGAAAVAEFNRAAQAGVPEDQGFETMAGFVSSLA 386

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           G +PARG+     G+ F VA AD RR+++V      
Sbjct: 387 GAIPARGDRFFWKGWVFTVAEADPRRVVKVRAARVK 422


>UniRef50_C9KMQ2 CBS domain protein n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KMQ2_9FIRM
          Length = 445

 Score =  294 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 98/286 (34%), Positives = 158/286 (55%), Gaps = 6/286 (2%)

Query: 6   SHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIA 65
           +H ++ ++++ GF     +     +    +E+  L+ +S +  LID+   D ++ V D  
Sbjct: 161 NHVANWVAHRMGF----HTASEGDDAHTEEEIRLLMEESHRQGLIDDTEVDFVDNVFDFT 216

Query: 66  DQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF 125
           D  VR+IM PR+ M+ L    T++E L  I+E   +R+P+  EDKDHI G L  KDL+  
Sbjct: 217 DLNVREIMTPRTDMVCLYLEDTMEENLHTILEEQLTRYPICHEDKDHIVGFLHVKDLMRI 276

Query: 126 MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDIL 185
           M    +  ++ ++ R+A++VPES  V  +LK  + QR  MAIV+DE+GG +G+VTIEDI+
Sbjct: 277 MAEGRKP-NLRRLARKALIVPESMDVSVLLKTMQKQRSQMAIVVDEYGGTAGMVTIEDIV 335

Query: 186 ELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQ 245
           E IVG+I+DE+DEE      +  +  ++V A   +E+  +       DE+VDTIGG +  
Sbjct: 336 EEIVGDIQDEFDEERPTA-ERRGKRIFSVDAKMLLEELEDILEIDIEDEDVDTIGGWLYD 394

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
             G  P  G+     G  F V   D  RI +V +   +D  +   +
Sbjct: 395 QIGQTPRVGQMAASGGNLFYVEEVDGVRITRVLIHCAEDLEKEHDE 440


>UniRef50_A5ZVW9 Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC
           29174 RepID=A5ZVW9_9FIRM
          Length = 315

 Score =  294 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 82/306 (26%), Positives = 161/306 (52%), Gaps = 15/306 (4%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFH------GEPKNRDELLALIRDSGQNDLIDEDT 54
           M D +       +    +   L  ++FH       +     E+++++ ++ +  ++ +D 
Sbjct: 1   MDDGSRLPRRGPAKVIDWIQGLFFRVFHFFKGEQEDSVTEKEIISMVDEAHEKGVLQKDE 60

Query: 55  RDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIE 114
            +M++ +    D+ V  +M  RS +     +  L + ++ ++E  +SR+PV  ED D I 
Sbjct: 61  AEMIQNIFAFEDKEVGVVMTHRSSVAAFAMDDLLKDVVNHMMEEENSRYPVCGEDMDDIR 120

Query: 115 GILMAKDLLPFMRSDAEA-----FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVI 169
           G++  KD L F   +  A       +  ++R+A  VPE++ + ++ +  ++++ HMA+V+
Sbjct: 121 GLIHYKDALKFFTQNPWAKFKPLKELPGLIRKATFVPETRHIGQLFRTMQARQVHMAVVV 180

Query: 170 DEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT 229
           DE+G  +G+VT+ED++E IVG+I DEYDE  D  FR    ++  +  LAS++D  +    
Sbjct: 181 DEYGQTAGIVTMEDLIEEIVGDIFDEYDESRDT-FRTQVDNSIIIDGLASLDDVEQELDI 239

Query: 230 HFSDEEVDTIGGLVMQAFGHLPARGE---TIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
            F D E++T+ G + +  GH+P+R +    I  +GY+FK+    +R I +V  +  +D  
Sbjct: 240 EFGDVEMETLNGYLTELLGHIPSREDLDKEIVANGYRFKILSLGNRTIGRVRAEKINDKE 299

Query: 287 QPKLDE 292
                E
Sbjct: 300 TKGESE 305


>UniRef50_D1Y9A3 CBS domain protein n=3 Tax=Propionibacterium acnes
           RepID=D1Y9A3_PROAC
          Length = 432

 Score =  294 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 86/272 (31%), Positives = 152/272 (55%), Gaps = 7/272 (2%)

Query: 27  FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQ 86
             G   +  EL  ++  +  +DLI+   R+M+  V ++ D   +++M+PR+ ++ + R +
Sbjct: 161 AEGPFTSEAELREMVDYAEASDLIEAGEREMIHSVFELGDTLTKEVMVPRTDVVYIPRTK 220

Query: 87  TLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE---AFSMDKVLRQAV 143
            L + + + + S  SR PV+ E  D I G++  KDL   +  + +     S++ ++R AV
Sbjct: 221 NLRQAMSLALRSGFSRIPVVGEGFDDIRGVVYLKDLSQRVLDNPDGYATESVESIMRPAV 280

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
           + P+SK VD++L+E +  R H+ IV+DEFGG +GLVTIEDI+E IVGEI DEYD  +   
Sbjct: 281 LCPDSKPVDQVLREMQRDRNHLVIVVDEFGGTAGLVTIEDIVEEIVGEIVDEYD-AEPTL 339

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
             ++    + + +   ++D  E F     D++V+T+GGL+ +    +P  G  I  +G +
Sbjct: 340 TEEIEDGVFRISSRLPVDDLGELFDLKVDDDDVETVGGLMAKELSVVPIPGSVIIWEGLE 399

Query: 264 FKVAMADSRR--IIQVHVKI-PDDSPQPKLDE 292
                A  RR  +    VK  P+++P  + D+
Sbjct: 400 ITAEKATGRRHQVDTCLVKRAPEETPDQEYDD 431


>UniRef50_B8KMV1 Magnesium and cobalt efflux protein CorC n=3 Tax=unclassified
           Gammaproteobacteria RepID=B8KMV1_9GAMM
          Length = 282

 Score =  294 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 143/286 (50%), Positives = 198/286 (69%), Gaps = 5/286 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MSDD + + +   +  G     ++Q F  EP+ R++L  +++ + +ND+I+ED+  +++G
Sbjct: 1   MSDDRNGNGNEEKSLLG----RIAQAFSSEPRTREDLQQILQLAMENDIIEEDSLSIIDG 56

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
            M ++  + RDIM+PR QM+ +K   TL+E L  I ES HSR+PVI E  D I GIL+ K
Sbjct: 57  AMQVSGMQARDIMVPRPQMVVIKSESTLEEVLQHISESKHSRYPVIGESPDDILGILLVK 116

Query: 121 DLLPF-MRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLV 179
           DLLP  +  D E F + ++LRQ+VVVPESKR++ +L+EFR  R HMAIVIDE+GGV+GLV
Sbjct: 117 DLLPQILSEDRENFDIRQLLRQSVVVPESKRLNVLLREFRENRNHMAIVIDEYGGVAGLV 176

Query: 180 TIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTI 239
           TIED+LE IVGEIEDE DEE+D   R++S   + VRAL  IEDFN+ F   FSD+E DTI
Sbjct: 177 TIEDVLEEIVGEIEDETDEEEDQFIRRISDDDFFVRALTPIEDFNDYFDVAFSDDEFDTI 236

Query: 240 GGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           GGLVM AFGH+P R E   I+G++FKV  AD R+I  + ++ P   
Sbjct: 237 GGLVMHAFGHMPTRNEITHIEGFEFKVINADQRKIHSLRLRPPGAE 282


>UniRef50_Q6MCC0 Putative uncharacterized protein n=2 Tax=Parachlamydiaceae
           RepID=Q6MCC0_PARUW
          Length = 457

 Score =  294 bits (754), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 81/251 (32%), Positives = 141/251 (56%), Gaps = 9/251 (3%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           +D   + ++EGVMD  D+  R++M+PR  + +L  + T+++   +I    +SR PV    
Sbjct: 205 LDPHDKKLIEGVMDFKDRIAREVMVPRVDIFSLAHDTTIEQAAVLIYNEGYSRIPVFKHT 264

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFS-------MDKVLRQAVVVPESKRVDRMLKEFRSQR 162
            D+I G+LM KD+L      +           +  +++  +  PE+K++  +L+EFR ++
Sbjct: 265 LDNIIGVLMYKDVLAKYMEFSRTQDTKILQAPISGLVKNVLYTPETKKISHLLQEFRKKQ 324

Query: 163 YHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIED 222
            H+AI++DE+GG  G+VTIEDILE IVG+I DEYDE ++  F  L    W + A  +I D
Sbjct: 325 VHLAIIVDEYGGTEGIVTIEDILEEIVGDIADEYDESEESLFVALPEGGWLIDARMTIFD 384

Query: 223 FNEAFGTHFS-DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
             E F    + D + DTIGG +    G++P++G  +    ++ KV  ++ RR+ ++ ++ 
Sbjct: 385 IEEQFDIEIAQDGDYDTIGGYIFHETGNIPSKGFVLTKPNFELKVIRSNDRRVEKLKIRS 444

Query: 282 PDDSPQPKLDE 292
                  + DE
Sbjct: 445 IR-LDSEEKDE 454


>UniRef50_C2ECT1 Hemolysin n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2ECT1_9LACO
          Length = 453

 Score =  294 bits (753), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 89/291 (30%), Positives = 153/291 (52%), Gaps = 9/291 (3%)

Query: 5   NSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDI 64
            + ++ ++ NK       ++        +  ++L +I +   N  +D +  +M++GV+ +
Sbjct: 147 PTVTAVSLINKHFVIKRDVTDTAEDPTASWQDILDMIEEGRNNGELDTNEYEMIDGVISM 206

Query: 65  ADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLP 124
            D+  R+IM+PR+    +         +D I+    SR PV  EDKD++ GI+  K L+ 
Sbjct: 207 HDKMAREIMVPRTDAFMVDVTNDNSRNIDSILGMDFSRVPVYHEDKDNVVGIVHIKTLVK 266

Query: 125 FMRS-DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIED 183
             R+   +  ++ + +R A  VPE+  +D +L + +  R  MAI++DE+GGV GLVT+ED
Sbjct: 267 LARNFGFDHITIRQAMRPAFFVPETMTLDELLFQMQKTRNQMAILLDEYGGVVGLVTLED 326

Query: 184 ILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLV 243
           +LE IVGEI+DE DE D + ++Q+S   + V+    I+DFN+ FGT     ++DTI G +
Sbjct: 327 LLEEIVGEIDDESDEPDQL-YQQISSDEFLVQGKMPIDDFNDEFGTDLKINDIDTIAGFL 385

Query: 244 MQAFGHLPARGETIDI------DGYQFKVAM-ADSRRIIQVHVKIPDDSPQ 287
           +   G +P   E + +             A   D  RI +V V +PD    
Sbjct: 386 IAKLGRIPDNDEVVSVTTESSEGDVVLTTAKIIDDARITEVKVTLPDALAS 436


>UniRef50_UPI0001BC3544 hypothetical protein BcroD2_01764 n=1 Tax=Butyrivibrio crossotus
           DSM 2876 RepID=UPI0001BC3544
          Length = 443

 Score =  294 bits (753), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 75/279 (26%), Positives = 137/279 (49%), Gaps = 8/279 (2%)

Query: 15  KKGFFSLLLSQ-LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
            KG   +   +     E    +E++ ++ +  +  +++    +M+  + ++ D+   DIM
Sbjct: 157 AKGILRIFGIKNPDAEENVTEEEIITMVNEGQEQGVLEAGEAEMITNIFELGDKHAGDIM 216

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA- 132
             RS +  ++   TLD  +   IE  +SRFPV   D D+I G +  +D L F R+     
Sbjct: 217 THRSNIEAVESTITLDNFIQNHIEGKYSRFPVYEGDIDNIVGTIHIRDALIFYRNIPNRK 276

Query: 133 ---FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
                +  +LR+  +VPE+  +D MLK+ + ++ HM IV+DE+G  +G+V++EDI+E IV
Sbjct: 277 KLLKDIKGLLRKPYMVPETMDIDDMLKDMQEKKIHMGIVVDEYGQTAGIVSMEDIIEEIV 336

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G I  +  ++++         T+ V  L  IED N   G     +  +T+ G ++   G 
Sbjct: 337 GNIL-DEYDDEEEVVEYAGDDTYVVDGLTDIEDINSLLGIKIESDGFETLNGFLISKLGR 395

Query: 250 LPARGET--IDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
           + +  ET  I+  G+ FK+       I +V +   D   
Sbjct: 396 IASENETEVIEAYGFSFKILEVTGNVIRKVEITKIDKKE 434


>UniRef50_C2HJY2 HCC HlyC/CorC family transporter n=2 Tax=Finegoldia magna
           RepID=C2HJY2_PEPMA
          Length = 414

 Score =  294 bits (753), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 76/268 (28%), Positives = 138/268 (51%), Gaps = 7/268 (2%)

Query: 17  GFFSLLLSQLFHGE-----PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
              + L+ +LF GE         +EL  L+  S +  ++     +++   +++ +    D
Sbjct: 146 NLLTRLVIKLFVGEDEDSSTLTEEELKTLVEVSEEEGVLKNQETEIMINALELKETLAVD 205

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM PR+ M ++       +  ++I    +SR PV  +  D I G+L  K+L   +  D  
Sbjct: 206 IMTPRTSMASVDIEDAESDLKEIIKNITYSRIPVYEDSIDDIIGVLHIKELAHKIIEDDR 265

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            F +  +L+ A    E   V  + K+ R++   ++I+IDE+GG SG+VT+EDILE +VGE
Sbjct: 266 DFKIRDILKPAFYAYEYIPVVDLFKQMRAKNISISIIIDEYGGTSGIVTMEDILEELVGE 325

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I+DEYD E +    ++S + + V     I++ NE F      ++ D+IGG V++    +P
Sbjct: 326 IDDEYDNEKE--VTKISENEYLVDPEMRIDEVNERFDLDIQSDKFDSIGGFVIELLDRMP 383

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHV 279
              + ++ +  +F V   D R+I Q+ +
Sbjct: 384 KSKDEVEFENLKFVVVNVDKRKITQLMI 411


>UniRef50_Q0C626 CBS/transporter domain protein n=7 Tax=Alphaproteobacteria
           RepID=Q0C626_HYPNA
          Length = 424

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 83/275 (30%), Positives = 127/275 (46%), Gaps = 4/275 (1%)

Query: 16  KGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
            G   L+            +E+   I        +D++    L G +D+ D  V D+MI 
Sbjct: 149 NGVLRLVGVGAAASPLSAEEEIRGAIDLHAAEGAVDKENHLRLVGALDLKDLTVEDVMIH 208

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF---MRSDAEA 132
           R  +  L  +    + +   + S H+R P+   +K+ I GIL AKDLL     +  D   
Sbjct: 209 RKNIYMLDADLEPRQLIMKALSSPHTRLPLYRGEKEEIIGILHAKDLLRAALPLGGDVSK 268

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +D +LR+   VPE+  V   L +F ++  H A+VIDE+G + GL+T+EDILE IVG I
Sbjct: 269 LDLDSILRKPWFVPETTPVQEQLNQFLARGQHFALVIDEYGELQGLITLEDILEEIVGAI 328

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DE+D +     R     +  V     I D N A G    DEE  T+ GLV+     +P 
Sbjct: 329 HDEHDVQIQ-GVRPQPDGSVNVDGWVPIRDLNRATGWDLPDEEAVTVAGLVIHEAQTIPE 387

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            G++    GY+F V      ++  V+V       +
Sbjct: 388 PGQSFVFHGYRFNVLRRQRNQVTGVNVSKAAPVAE 422


>UniRef50_D1VTC9 Integral membrane protein n=1 Tax=Peptoniphilus lacrimalis 315-B
           RepID=D1VTC9_9FIRM
          Length = 412

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 82/272 (30%), Positives = 133/272 (48%), Gaps = 1/272 (0%)

Query: 12  ISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +   + F  L  S   +      ++L   +       L+D +   M+E VMD  D   +D
Sbjct: 142 LKISQVFLKLTGSFDINEPLITEEDLYDAMNRGKAEGLLDHNESLMIENVMDFRDSYAKD 201

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM PR+ ++ +    +  E +D+I +   SR PV  ++ D+I GIL  KDL   M     
Sbjct: 202 IMTPRTDIVAIDIESSYSEIIDLICKENFSRMPVYEDNIDNIIGILNVKDLF-MMNKHKS 260

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
                   ++     E K V  +  + R+ +  +AIV DE+GG +G++TIED++E IVG 
Sbjct: 261 LKENKSFFKKPYFTYEYKEVSSLFSDMRANKISVAIVADEYGGTTGMITIEDLIEKIVGA 320

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DEYD EDD D  +L  + + V    +++D N+  G      E D+IGG +++     P
Sbjct: 321 INDEYDNEDDEDIIKLGPNKYLVDGAMNLDDLNQLTGLELESTEFDSIGGFIIEKIDRFP 380

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
            + E I +D  +F V      RI +V ++I  
Sbjct: 381 KKNEVIILDNLKFTVKKTSKNRIDKVLLEIKK 412


>UniRef50_D1CH59 Putative uncharacterized protein n=1 Tax=Thermobaculum terrenum
           ATCC BAA-798 RepID=D1CH59_THET1
          Length = 431

 Score =  293 bits (752), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 72/274 (26%), Positives = 134/274 (48%), Gaps = 6/274 (2%)

Query: 9   SDTISNKKGFFSLLLSQLFHG--EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIAD 66
           +   +   G   L   Q         + +EL  L+R   +  +++     +     + AD
Sbjct: 159 TALNAIGNGILLLFGLQPATETESVHSVEELRFLVRGMREAGVVEPSEARIATRAFEFAD 218

Query: 67  QRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM 126
                +M PR+++  +  +  L++ +     + HSR  V   D D+I G +   D+L  +
Sbjct: 219 VTAGSVMTPRTELEAVPVDTPLEQLVAKAATAQHSRLLVYDGDLDNILGDVHVHDILRAV 278

Query: 127 RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
            +      +  ++R A++VPESK  D +L+E R  R  +A+V+DE+GG +G+VTIED++E
Sbjct: 279 YA-RRPVKLRDLIRPALLVPESKPADDLLEEMRKARRPIAVVVDEYGGTAGIVTIEDLVE 337

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQ 245
           ++VG IE+E         +        +  L  + +  E  G    +E+ V+T+GGL+M 
Sbjct: 338 VLVGPIEEELPPGVREAMQPEEPQ--VLDGLMRLRELEEMLGVEIEEEDHVETLGGLIMA 395

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHV 279
             G +P  G+ ++I G++ +V   D  R+  V +
Sbjct: 396 RLGRIPQEGDEVEIGGHKLRVEKMDGMRVDSVRL 429


>UniRef50_A9VF50 Putative uncharacterized protein n=6 Tax=Bacillus
           RepID=A9VF50_BACWK
          Length = 437

 Score =  293 bits (752), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 76/265 (28%), Positives = 146/265 (55%), Gaps = 5/265 (1%)

Query: 21  LLLSQLFHGE--PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
           +   +           +EL  ++ +S +   I++     +  + +  ++  ++IM+PR++
Sbjct: 166 MFGLKPASEHDVAHTEEELRLILSESYERGEINQAEYKYVNNIFEFDNRIAKEIMVPRTE 225

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLL-PFMRSDAEAFS-MD 136
           +I L  + +L + + +I +  ++R+PV  EDKD I G++  KD    +M  + + F+ + 
Sbjct: 226 IIGLHVDNSLADHMKIIRDEKYTRYPVFGEDKDEIIGMVNVKDFFIRYMNKETKEFNSIQ 285

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
              R  + V E+  +  +L + + +R  +A++ DE+GG +G+VTIEDILE IVGEI DEY
Sbjct: 286 SYTRPVIEVIETIPIHNLLLQMQKKRIPLAVLYDEYGGTAGIVTIEDILEEIVGEIRDEY 345

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           DE++    +Q++     V     I + N+  G H +D +VDTIGG ++     +   G+T
Sbjct: 346 DEDERPPIQQMNEGHLVVEGKVLISELNDLLGLHMNDSDVDTIGGWILMQNYDI-QEGQT 404

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKI 281
           ++ +GY FK+   D  +I +V ++ 
Sbjct: 405 VNSEGYAFKILSKDPHQIKRVEIQK 429


>UniRef50_A8ZTS5 Putative uncharacterized protein n=2 Tax=Desulfobacteraceae
           RepID=A8ZTS5_DESOH
          Length = 422

 Score =  293 bits (751), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 76/276 (27%), Positives = 137/276 (49%), Gaps = 4/276 (1%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPR 76
            F   L  ++        +EL A+I  + +   ID + ++ +  +  + D    + M P 
Sbjct: 142 NFIPRLTGKMKPIPVMTEEELKAIIEVTEEEGEIDNEEKEFIHNIFKLDDTSASESMTPT 201

Query: 77  SQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMD 136
           + M  +  N+ L   L  I+++ ++R PV      +I GIL  KD+           ++ 
Sbjct: 202 TDMFAVDVNKKLP--LGAILKTGYTRIPVYEHHIGNIIGILNVKDVFRHYVQAKGPPNIR 259

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
            ++ +   +PESK+++ +LK+F+ +++HMAIVI+E G V GL+T+ED+LE +VG+I DE 
Sbjct: 260 SLMSKPYFIPESKKLNSLLKQFKLRKHHMAIVINEHGEVLGLITLEDVLEELVGDIIDET 319

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGE 255
           D   +    ++ + TW V     IE+ N     H  +  E DT  G ++   G +P  GE
Sbjct: 320 DR-YEPHIVKVKKQTWLVLGKTHIEETNAKLPMHIPESGEYDTFSGYLLYRIGRIPEEGE 378

Query: 256 TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
            I ID +   +   ++ RI+ + V+     P    +
Sbjct: 379 IITIDNFVITIKRMEANRILSLLVEEKASPPSLDAE 414


>UniRef50_C2BH63 HCC HlyC/CorC family transporter n=2 Tax=Anaerococcus
           RepID=C2BH63_9FIRM
          Length = 415

 Score =  293 bits (751), Expect = 6e-78,   Method: Composition-based stats.
 Identities = 80/271 (29%), Positives = 143/271 (52%), Gaps = 4/271 (1%)

Query: 12  ISNKKGFFSLLLS--QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           +     F + L+       G+    ++L  ++  S +  +I++   +++  V +  D  V
Sbjct: 145 LQAITNFLTRLIIGENAQKGDIVTEEDLKTIVDVSEEQGVINDQESEIINNVFEFGDSDV 204

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
            DIM  R+ M  +  +    E  D +    HSR PV  +  D+I GIL  KD++ F+  D
Sbjct: 205 EDIMTARTNMEAIAVDMEDKELKDFLKNCKHSRIPVYGKSIDNIIGILHMKDIVAFIAED 264

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            E  ++++++R A  V ++  +  + K+ R +   +AIVIDE+GG SG+VTIEDI+E +V
Sbjct: 265 KE-LNIEEMVRPAFYVYDNMHIFDLFKQMRGENVSLAIVIDEYGGTSGIVTIEDIVEELV 323

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           GEIEDEYD   +    +++   + V     I DFN+ F T     + D+IGG ++   G 
Sbjct: 324 GEIEDEYDTHLET-VLKINDKEYLVNPSIHINDFNDYFDTDLEQIKNDSIGGFLIDKLGR 382

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
           +P  G++++ DG +  V   +  ++  + V+
Sbjct: 383 IPKLGDSVEEDGIKISVVQINRYKLEMLKVE 413


>UniRef50_Q3ZYX1 Probable hemolysin-related protein n=5 Tax=Dehalococcoides
           RepID=Q3ZYX1_DEHSC
          Length = 424

 Score =  292 bits (750), Expect = 6e-78,   Method: Composition-based stats.
 Identities = 74/277 (26%), Positives = 144/277 (51%), Gaps = 3/277 (1%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
             GF  L             D++ A+I    +   ++ED  ++L  V + +D+ VR++++
Sbjct: 149 SSGFTKLFGGPSLKSSLVAEDDIRAMITVGHKEGTVEEDKAELLHKVFEFSDRPVREVIV 208

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF- 133
           PR ++ ++++  TL + LD+  ES  SRFPV  E+ D++ GIL  KD+L  +        
Sbjct: 209 PRPEVESVEKGSTLKDFLDLYAESPMSRFPVYEENMDNVLGILSIKDVLMALAKGTHTPQ 268

Query: 134 -SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
            S+D ++R A   PE+K + ++  E R + + M +VIDE+GG +G+V++  ++E IVG +
Sbjct: 269 DSVDDLMRPAYFAPETKPIGKLFNEMREKNFRMCVVIDEYGGTAGIVSLSRLMEEIVGPV 328

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DE  + +  D+  ++ +T+ V     IE+ N        + + +TI GL++   G++P 
Sbjct: 329 GDELADAEK-DYESINEYTFQVDGSMRIEEANVEMDLDLPEGDYETIAGLILDRLGYIPK 387

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           +G+ I +   +  +      +I +V +     +    
Sbjct: 388 QGQQIKLQNLKVVITHMKGMKIDEVLITKEKRAASKN 424


>UniRef50_Q6N606 Probable HlyC/CorC family of transporters with 2 CBS domains n=12
           Tax=Alphaproteobacteria RepID=Q6N606_RHOPA
          Length = 431

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 73/275 (26%), Positives = 125/275 (45%), Gaps = 3/275 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           + K   +LL       +  + +E+ +L+ ++    +++   R M+ GVM + D+ V  +M
Sbjct: 157 SGKAMLALLGQSGEPEDKISEEEIHSLVMEAETAGILEPGERQMIAGVMRLGDRPVGAVM 216

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR ++  +  +   D+       S HSR P    D+D   GI+ +KD+L          
Sbjct: 217 TPRPEVDMIDLSDPPDQIRATFASSPHSRLPATDGDRDDPIGIIQSKDVLEVYLRGETP- 275

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
               ++R A V+P S      L   R+   HM +V DEFGG  G+V+  DILE IVG   
Sbjct: 276 DFRALVRDAPVIPASADARDALIMLRNASVHMGLVYDEFGGFEGVVSTADILESIVGAFS 335

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPA 252
            E D   +    +    ++ V     +++F +  G       +  T+ GLV+   G LP+
Sbjct: 336 SE-DGPPEPAAVRRDDGSYLVAGWMPVDEFGDLLGMPVPAPRDYHTVAGLVLSHLGALPS 394

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            G+  D  G++F++   D RRI ++      D   
Sbjct: 395 VGDKFDFQGWRFEIMDLDHRRIDKILASRLPDDEA 429


>UniRef50_D1BMR3 Transporter-associated region n=3 Tax=Veillonella
           RepID=D1BMR3_VEIPT
          Length = 443

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 70/251 (27%), Positives = 132/251 (52%), Gaps = 3/251 (1%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + +E+  +I  S +   +D+   ++++ V +  D+  +++M+PR  +  +      DE +
Sbjct: 184 SEEEIRMMISRSHEEGQLDQVESELIDNVFNFVDRMAKEVMVPRQDVDCVFVEDGYDEAM 243

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVD 152
            VI    H+R+P+  EDKDHI G++  KDL+   R +     +  + R  + VPE  ++ 
Sbjct: 244 KVIRSKVHTRYPLCVEDKDHIIGLVHIKDLME--RPNQARKDLRNIKRDILTVPEVMKLS 301

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+  R++R ++A+V+DE+GG+ GLV +EDI+E +VG+I+DE++          +  ++
Sbjct: 302 TLLQYMRTRRIYLAVVVDEYGGMVGLVGLEDIIEELVGDIQDEHEPHLPATM-SYADGSF 360

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
                  +++  E       + + DTIGG V       P  G+T+D  GY F+V      
Sbjct: 361 EFDGKVLVDEVEEIMNIEIDNSDSDTIGGYVFGLLERTPIVGDTVDAHGYTFEVTQMQGY 420

Query: 273 RIIQVHVKIPD 283
           RI ++ V    
Sbjct: 421 RISRIKVTPIP 431


>UniRef50_C4L4N6 Putative uncharacterized protein n=2 Tax=Bacillales
           RepID=C4L4N6_EXISA
          Length = 424

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 72/268 (26%), Positives = 133/268 (49%), Gaps = 2/268 (0%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +  K     ++           +EL  L+    +  ++ E   +++       D  V D+
Sbjct: 147 TGLKKLTLRMIGMKDKEPSVTEEELKVLVDMGEEEGVLGETEAELVHSAFAFNDITVDDV 206

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           + PR  ++ +  + +LDE  D I    HSR PV  +  D++ G+L  +D L  M  D E 
Sbjct: 207 LTPRIDILAVDIDDSLDEIKDTIFSGGHSRLPVYKDSIDNVIGVLSERDFLRSMMKD-EV 265

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +  ++R    V    ++  +L   + ++ HMA+V+DEFGG +GL+T+ED+LE +VG+I
Sbjct: 266 TDVRSLIRPLTYVSPQTKLIELLPILQQKQSHMAVVLDEFGGTAGLITLEDMLEELVGDI 325

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DE+D E  +  R+L    +   A  ++++F E  G    D + +T+GG  ++  G +P 
Sbjct: 326 WDEHD-ESVVYLRRLREGVYECMADMNVDEFAEEMGIAEPDVDSNTMGGWFVELLGDIPE 384

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVK 280
           +G  +      F V   + RR+ ++ V+
Sbjct: 385 KGAQVTYQDMTFTVLHVEKRRVRKLLVE 412


>UniRef50_C4GBW1 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
           DSM 14600 RepID=C4GBW1_9FIRM
          Length = 458

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 86/280 (30%), Positives = 140/280 (50%), Gaps = 4/280 (1%)

Query: 15  KKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
                 L+ +      E    +EL  ++  S +  +I+ + R+ +  + D  D  VR++M
Sbjct: 149 ANAMIRLMGTDPHRRRENLTEEELRTIVDVSQEAGVIEHEERNYIHNLFDFTDSNVREVM 208

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IPR  +     N + D+ + V      +R PV  E+ D I GI+  KDLL  +  D   F
Sbjct: 209 IPRIDVTVANVNWSYDKLISVFAGCMFTRLPVYDENSDSIVGIINMKDLL--LVKDKAHF 266

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           S+   LR A    E K    + +E R     MAIV+DE+G  +G++++ED+LE +VGEI 
Sbjct: 267 SLRDYLRSAYFTFELKNTRELFEEMRQNSIAMAIVMDEYGAFAGIISLEDLLEELVGEIR 326

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DEYD  ++ D  QL+   + V    ++ED        +  E+ DTIGG +   F H P +
Sbjct: 327 DEYDSNEEDDIVQLNEREYLVVGSMNLEDLMSIIPLGYESEDYDTIGGYLTGEFDHFPNQ 386

Query: 254 GET-IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           GET +D +G   KV      RI ++ +++P+   +   +E
Sbjct: 387 GETYVDSNGAILKVEKVRKNRITKILIRLPEQIAKEVDEE 426


>UniRef50_C3X3R1 Magnesium and cobalt efflux protein n=1 Tax=Oxalobacter formigenes
           HOxBLS RepID=C3X3R1_OXAFO
          Length = 324

 Score =  291 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 119/293 (40%), Positives = 173/293 (59%), Gaps = 8/293 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           M +   HS +T    + F   L S     EP  R ELL ++ D+ +  LID +   M+EG
Sbjct: 32  MPEHPEHSQNTNKPARTFLDRLAS-FISSEPDTRTELLDILHDAHERKLIDSECLSMIEG 90

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V  + D  VRD+MIPRSQM  +   + + E +  ++E+ HSR+P I  D + I GI+ AK
Sbjct: 91  VFRLFDSAVRDVMIPRSQMYVIDITRPVSEWIGEVMENGHSRYPAIEGDAEKIVGIVHAK 150

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL +       FS+ ++L  AV +PESKR++ +L++FR+   HMAIV+DEFG +SGLVT
Sbjct: 151 DLLHYREEG---FSVREILHPAVFIPESKRLNVLLRDFRNTHNHMAIVVDEFGNISGLVT 207

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRH----TWTVRALASIEDFNEAFGTHFSDEEV 236
           IED+LE IVG+IEDE+D+++D     L        W + AL  ++DFN   GT  +D  V
Sbjct: 208 IEDVLEQIVGDIEDEFDDDEDDKIVALKAGATGPRWRIPALTEMDDFNRTLGTKLADSRV 267

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
           DTIGG V    G +P +G+  DIDG  F+V  AD+R++  + V+      +  
Sbjct: 268 DTIGGYVANHLGRVPHKGDAFDIDGLHFEVVRADARQLHTLVVEKKPAIAEKN 320


>UniRef50_A8PND0 Magnesium and cobalt efflux protein CorC n=1 Tax=Rickettsiella
           grylli RepID=A8PND0_9COXI
          Length = 289

 Score =  291 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 121/270 (44%), Positives = 179/270 (66%), Gaps = 3/270 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           N++ +FS     +F   PKNR +L+ L+  + Q +L++     MLEGV+ I+D +VRDIM
Sbjct: 15  NRQSWFSRF--NVFKQAPKNRKQLIELLHYAKQRNLLNSQALKMLEGVLQISDSQVRDIM 72

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           IP +++  +     L E L ++IESAHSRFPVI++++  + G+LMAKDLL +       F
Sbjct: 73  IPHAKITAISAKAPLSEILPLVIESAHSRFPVINDER-QVIGLLMAKDLLKYNPLSQNDF 131

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           ++  +LR  V +PESKR+D +LKEF+ + YHMAIV+DE+G  SGLVTIED+LE IVGEIE
Sbjct: 132 NIHTILRPVVFIPESKRLDSLLKEFQRKHYHMAIVVDEYGAASGLVTIEDVLEEIVGEIE 191

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DE+D +++I  ++ + H + V+A+  IE FN  F +H   ++ DTIGG++   FG+LP R
Sbjct: 192 DEHDTDEEIFIQEQTPHQFIVKAIMPIEAFNAFFNSHLETDQFDTIGGVIANRFGYLPKR 251

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           G +  I  + FKV  AD+R I  + V I  
Sbjct: 252 GASTTIYPFHFKVLRADNRVIRLLQVTIEP 281


>UniRef50_UPI0001C360F2 putative hemolysin-related protein n=2 Tax=Clostridium hathewayi
           DSM 13479 RepID=UPI0001C360F2
          Length = 436

 Score =  291 bits (747), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 82/272 (30%), Positives = 136/272 (50%), Gaps = 8/272 (2%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
              LL +         +ELLA++ ++ Q+  IDE    +++  ++  +    DI  PR  
Sbjct: 166 LLSLLIRTSGDPGITEEELLAIVEEAKQDGGIDEQEGSLIKSAIEFTELEATDIATPRVD 225

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           +  +  +   +E   V  E+ +SR PV  E  D I GI+  KD    M        ++ +
Sbjct: 226 VTGISIDADKEEIAAVFDETGYSRLPVYKETIDDITGIIYQKDFYNRMYRG--TCGVEAI 283

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R A+ V +SK+++ +LKE +  + H+A+VIDEFGG  G+VT+EDILE +VGEI DE+D 
Sbjct: 284 VRPALYVAKSKKINVLLKELQKNKMHIAVVIDEFGGTMGIVTLEDILEELVGEIWDEHDV 343

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD--TIGGLVMQAFGHLPARGET 256
               +  ++S   + V   AS+E      G   S+E  +  T+ G VM+    +P  G+ 
Sbjct: 344 VVQ-EIEKISDREYLVSGNASVEKLMGELG---SEETFESFTVSGWVMELAERIPEEGDV 399

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
              D     V     RR+ QV + +  +  +P
Sbjct: 400 FYYDHMSITVIKMRDRRVEQVRLVLEAEPMEP 431


>UniRef50_C1A9X1 Hypothetical membrane protein n=1 Tax=Gemmatimonas aurantiaca T-27
           RepID=C1A9X1_GEMAT
          Length = 433

 Score =  291 bits (747), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 80/278 (28%), Positives = 138/278 (49%), Gaps = 6/278 (2%)

Query: 15  KKGFFSLLLSQLF--HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
                     +     G   + +EL  L+  +  +  +DE    ML GV D  ++R  D+
Sbjct: 160 ANRMLKWFGIEPVSEGGHVHSPEELRLLVMQARAHGTLDESDSAMLAGVFDFHNKRAVDV 219

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR++M+ +  +    E  +++    +SR+PV  E  D I G+ +AKD   ++R ++E+
Sbjct: 220 MRPRTEMVAIAEDVDQQELEEILRRERYSRYPVYRETADDIVGVFLAKDF--WLRENSES 277

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
           F + +VLR+ + VP ++  +R+L + R  R H+A+V+DEFGG +G+VT+ED++E +VG+I
Sbjct: 278 FELRQVLREPLFVPATRTAERVLDDLRRTRAHLAVVLDEFGGTAGIVTMEDLVEEVVGDI 337

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DEYD         L      +    S+ D          + +  T+GG      G LP 
Sbjct: 338 ADEYDPLSRDAL--LFDGVLELAGSMSLVDVRSDHKLPIPEGDWSTLGGYAFATLGRLPH 395

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
            G+ +   G   +V   D RR+  + V    +S +P  
Sbjct: 396 VGDRVAYPGGDLEVVAMDGRRVAALRVHKRVESTEPAA 433


>UniRef50_B1I646 Putative uncharacterized protein n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I646_DESAP
          Length = 431

 Score =  291 bits (747), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 80/267 (29%), Positives = 142/267 (53%), Gaps = 6/267 (2%)

Query: 19  FSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
             L   +   + +    DEL  +I        +D + + +L  V D  D    D+M+PR+
Sbjct: 169 LRLFGLKPGVNEDQVTEDELKQII---VNQSTLDREEQRLLWDVFDFGDAVAYDVMVPRT 225

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDK 137
            ++ ++ + ++ + L ++ E+ HSR PV  ++ D I+GI   KDL+P++    E   ++K
Sbjct: 226 DVVGVETSTSVADTLRLMSETGHSRIPVYGQNLDDIKGIAGIKDLVPYLLRGEEQAPVEK 285

Query: 138 VLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYD 197
           V+R A VVP +  + ++L++ + +   MA+++DEFGG  G+VT+E +LE +VGEI DEYD
Sbjct: 286 VVRPAYVVPNTVPIRQLLRDLQKRGVSMAVIVDEFGGTDGVVTVETLLEELVGEIRDEYD 345

Query: 198 EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGET 256
            ED  +          V+  A +++ N        + EE  TI G ++     +P  G+ 
Sbjct: 346 REDQ-EILSSEDGQAIVKGSAGVDEVNRQLKLAIPESEEYHTIAGFILDQLNKVPKAGDR 404

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPD 283
           + +DG   +VA   + RI+ V +K  D
Sbjct: 405 VTLDGTVLEVAKMKANRILMVSIKKED 431


>UniRef50_A6U9C9 Putative uncharacterized protein n=2 Tax=Sinorhizobium
           RepID=A6U9C9_SINMW
          Length = 430

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 65/269 (24%), Positives = 136/269 (50%), Gaps = 4/269 (1%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
             ++  +    +    +E+ A++ +  ++  I++   +ML  ++ + D+ V+ IM  R++
Sbjct: 162 MRIMGMRPEDADHVTEEEVQAIMAEGVESGAIEKSEHEMLRRIIRLGDRNVKTIMTHRTE 221

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           +  +     L+     I +S HSR+PV+      + G ++AK++L   ++    F++   
Sbjct: 222 VSFIDIQDDLETIGHKIRQSGHSRYPVVDGPAGDVIGAVLAKEILNVSQTGK--FNIRDY 279

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R  + +PE+    + L+ F++   +MA+++DE+G   G++T  DILE IVG I   YD+
Sbjct: 280 VRDILTLPETASCLKALEAFKTSSINMAMIVDEYGSTEGIITTADILEAIVGIIPSNYDD 339

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTH--FSDEEVDTIGGLVMQAFGHLPARGET 256
            +          ++ V     I++ +   G     +D + +TI G ++Q     P  G+T
Sbjct: 340 SEHALIHLRDDGSYLVDGRTPIDEIHLQIGIEGIDADSDFETIAGFLVQQLRKSPEEGDT 399

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
            +  GY+F+V   D RRI ++ V    ++
Sbjct: 400 AEAHGYRFEVIDMDGRRIDKILVSRAGEA 428


>UniRef50_A1QYK9 Magnesium and cobalt efflux protein CorC n=21 Tax=Borrelia
           RepID=A1QYK9_BORT9
          Length = 259

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 88/231 (38%), Positives = 132/231 (57%), Gaps = 2/231 (0%)

Query: 54  TRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHI 113
              +L+    + +  V++IMIPR  ++ +  + + DE L V+  S HSRFPV  E  D I
Sbjct: 28  ETSLLKNFNSLKETIVKEIMIPRISVVFVDYSWSKDEILKVVTSSNHSRFPVYRETIDDI 87

Query: 114 EGILMAKDLLPFM-RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEF 172
            GI+  KD+L  M + D     +  ++R+ + VPESK++D +LKEF+    H+AIV+DE+
Sbjct: 88  IGIIHTKDILLHMWKRDFYEIDLRDIMRKVMFVPESKKIDSLLKEFQENHVHIAIVVDEY 147

Query: 173 GGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS 232
           GGV+GLVT+EDILE IVG+I+DE+D E D +   L   ++   A   IED NE  G    
Sbjct: 148 GGVAGLVTLEDILEEIVGDIQDEFDNELD-EIVPLDDGSYLCTARVLIEDLNEKLGLSLP 206

Query: 233 DEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           D + DT+GG V   FG +P + E I  +   F +     R I  + +   +
Sbjct: 207 DGDFDTLGGFVYDLFGRIPLKNEKIKYNNLTFTIKNMHQRNIKVIKISQKE 257


>UniRef50_Q87DZ3 Hemolysin n=20 Tax=Xanthomonadaceae RepID=Q87DZ3_XYLFT
          Length = 448

 Score =  290 bits (744), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 68/276 (24%), Positives = 134/276 (48%), Gaps = 4/276 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           + +    +             +E+  L+ +S +  +ID+  R+M+  VM + D+    +M
Sbjct: 166 STQLVLRVFGFGKIPSSAVTEEEIRLLVAESHEAGVIDDYERNMMNRVMRLGDRTADSLM 225

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD-AEA 132
            PR+++  L  +  L+  L+++ E   SR+PV       I GIL  K ++  + S     
Sbjct: 226 TPRNRIAWLDNSADLEHNLEIMREHQFSRYPVYRSSDQDIVGILEVKSVITRIDSQTQTT 285

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
            S+ + L + V V ES    ++L+ FR ++  MA+V+DE+G + GLVTI D++  ++G +
Sbjct: 286 LSLFQELCEPVFVSESTHALKLLEIFREEQQSMALVVDEYGEILGLVTISDLMGAVIGRL 345

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEE---VDTIGGLVMQAFGH 249
           ++  + ++D         ++ +     IE+  E  G    D E     T+ G+ +  FG 
Sbjct: 346 QNVENTDEDALMVTREDGSFLIDGTLPIEELREVLGAELPDGEENNYHTLAGMCISYFGR 405

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           +P  GE  D  G++ ++   D  RI ++ ++  +  
Sbjct: 406 IPHVGEYFDWAGWRIEIVDLDGARIDKLLLQRLNKE 441


>UniRef50_C6LCF2 CBS domain protein n=1 Tax=Bryantella formatexigens DSM 14469
           RepID=C6LCF2_9FIRM
          Length = 289

 Score =  290 bits (744), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 74/279 (26%), Positives = 145/279 (51%), Gaps = 9/279 (3%)

Query: 12  ISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           + +  G  S  L +   G  +  +E+++++ +  +  +I E    M++ + D+ D+  +D
Sbjct: 2   LKSLSGLLSRKLGKNPSGSDEYEEEIISMVNEGHEQGVIQESQAQMIQNIFDLTDKEAQD 61

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M  R  +  ++    L + L  +++  HSRFPV  ++ D+I GIL  KD + +   + +
Sbjct: 62  VMTHRRNITAIEGTMNLKDALAFMLDDTHSRFPVYLDNLDNIIGILFLKDAMRWHTRNPD 121

Query: 132 -----AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
                   +  +LR+AV +PE++ +  + K  ++Q+  M IV DE+G  +GLV +EDILE
Sbjct: 122 YDNWQIKDIPSLLRKAVFIPETRDLSPLFKSMQTQKLQMVIVSDEYGQTAGLVAMEDILE 181

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            IVG I+DEYD ++ +   +     + +   A +++ +EA      D E +T+ G ++  
Sbjct: 182 EIVGNIQDEYDNDEPV-IEKAGDD-FLISGFAPLDEVSEALQLSLDDVEFETLNGFLISK 239

Query: 247 FGHLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPD 283
            G +P+  +   I  DGY F++    ++ I +V      
Sbjct: 240 LGRIPSDDDRSEIITDGYSFRILSVANKTIERVRAHRLP 278


>UniRef50_B6FN86 Putative uncharacterized protein n=2 Tax=Clostridium
           RepID=B6FN86_9CLOT
          Length = 282

 Score =  289 bits (742), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 75/275 (27%), Positives = 137/275 (49%), Gaps = 10/275 (3%)

Query: 17  GFFSLLLSQLFHGEPKNR---DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
              S +         +     + ++ ++ +  +  +       M+  +    ++  + IM
Sbjct: 6   NLLSRMRKIFSGEMEEGEDAAEAVMDMVDEGYRQGVFLSSEAQMIRNIFAYGEKDAKSIM 65

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--- 130
             R  M+ L   +TL+  L  I+E   SRFPV  ED D I G +  +D +    ++    
Sbjct: 66  THRKHMVALDGEETLENALTFILEQNKSRFPVYEEDIDSIIGTIHLRDAMKCYFNEQLRH 125

Query: 131 -EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
                +++ +R    +PE++ +D++LK+ +  +YHMAIVIDE+G  +GLVT+EDI+E IV
Sbjct: 126 IPIKQLEEYIRPVSFIPETRSIDKLLKKMQEGKYHMAIVIDEYGQTAGLVTMEDIIEEIV 185

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGH 249
           G I+DEYDEE+++  RQ +  ++    +  +ED  E  G  F +E+ +T+ G ++     
Sbjct: 186 GNIQDEYDEEEEL-IRQEADGSYLADGMTEVEDLEELLGIQFEEEDYETLNGFLIFHLER 244

Query: 250 LP--ARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           +P       +   GY F+V   ++  I  V +K  
Sbjct: 245 IPTEEENCVVSYGGYDFQVLSMENNIIKTVQIKKR 279


>UniRef50_Q6MC55 Putative uncharacterized protein n=1 Tax=Candidatus Protochlamydia
           amoebophila UWE25 RepID=Q6MC55_PARUW
          Length = 419

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 77/266 (28%), Positives = 137/266 (51%), Gaps = 6/266 (2%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
            + LL++    +    +E+  ++ +  Q  +I E   DM+E +  + ++RV  +MIPR  
Sbjct: 153 IAKLLARGKTHDKITEEEIKLILEEGSQAGVIREAEHDMVESIFRLGNRRVGILMIPRMD 212

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138
           +  L  N   +E L  I  S H+RFPV   + D + G++  KD+L  +    + F +  +
Sbjct: 213 IEWLDLNHHTEELLQQINISPHNRFPVCDGELDKVIGLVTTKDVLNEILKTGK-FDLKTL 271

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           ++  + VPE+ RV ++L  F+    H+A+V DE+GGV GL+T+ D+LE IVG++      
Sbjct: 272 VKAPLFVPENMRVVQLLDLFKKTPDHIALVTDEYGGVQGLITLHDVLESIVGDVPS-TSI 330

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFGHLPARG 254
             +    Q    +W V  +  I++  E F      +EE     T+GG  M+  G +P  G
Sbjct: 331 LPETQIIQRKDGSWLVDGMLPIDELKEQFDFDSLPEEEKGTYRTLGGFCMRQIGSIPNIG 390

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVK 280
           +T     ++F+V   + RR+ +V + 
Sbjct: 391 DTFTWQKFRFRVVKMNGRRVEKVLIH 416


>UniRef50_C0W312 HCC HlyC/CorC family transporter n=1 Tax=Actinomyces urogenitalis
           DSM 15434 RepID=C0W312_9ACTO
          Length = 432

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 86/263 (32%), Positives = 151/263 (57%), Gaps = 7/263 (2%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           ++L  +I + G+ + I+++ R ML  V+++    VR++M+PR+ M+T+  ++ +   + +
Sbjct: 168 EDLREMIDEIGEAETIEDEDRQMLRSVVELGQTLVREVMVPRTDMVTIDADKPVSAAMRL 227

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE--AFSMDKVLRQAVVVPESKRVD 152
            I+S  SR PVI +D D + G++  KDLL  + +  E     +   +R+AV VPE+K  D
Sbjct: 228 FIKSGFSRVPVIGQDADDVRGVVYLKDLLRRLDAQPEYAQREVVTCMREAVYVPETKLAD 287

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
            +L+E ++   HMA+ +DE+GG +GLVT+ED+LE +VG++ DE+D  +  +   L    +
Sbjct: 288 DLLREMQTDSVHMALAVDEYGGTAGLVTMEDLLEEVVGDMTDEHDHAE-PEVEDLGDGVY 346

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V A  S+++  E FG    D++VDT GGL+ +A G +P  G + ++ G       A  R
Sbjct: 347 RVPARLSLDELGELFGLEIDDDDVDTAGGLLTKAIGRVPLPGASGEVQGLHLVADQATGR 406

Query: 273 R--IIQVHV--KIPDDSPQPKLD 291
           R  +  + V    PD +     D
Sbjct: 407 RRQVTSLLVSASRPDTAQTTSKD 429


>UniRef50_A9I003 Magnesium and cobalt efflux protein n=5 Tax=Bordetella
           RepID=A9I003_BORPD
          Length = 298

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 112/295 (37%), Positives = 180/295 (61%), Gaps = 7/295 (2%)

Query: 1   MSDD----NSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRD 56
           MSD     +++++      K     +L+ L   EP++R+ + A++  +    L+D ++  
Sbjct: 1   MSDPYPANDANTNRARKPTKSLLDRMLA-LVRREPEDREGIKAVLDAAHDRALLDVESYG 59

Query: 57  MLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGI 116
           M++G + ++++ V DIM+PRS+M  L  +Q L + L  IIE+AHSRFPV  +D+D+I GI
Sbjct: 60  MIKGALAMSERSVADIMVPRSRMDLLDVSQPLPQQLAFIIETAHSRFPVYEDDRDNIIGI 119

Query: 117 LMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVS 176
           L+AKDLL  M        +  ++R AV +PE+KR++ +L++FR+   H+AIVIDE GG+S
Sbjct: 120 LLAKDLLRGMLEPG--IELRSLIRPAVFIPEAKRLNVLLRDFRASHNHLAIVIDEHGGIS 177

Query: 177 GLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEV 236
           GLVT+ED+LE IVG+IEDE+D++D+        + W + A   I  FNEAF T   D+E 
Sbjct: 178 GLVTMEDVLEQIVGDIEDEFDDDDEQSIFPEGDNQWRLMASTEISHFNEAFSTDLPDDEY 237

Query: 237 DTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           D++GG +    G +P RG++        +V  AD+RR + +  K   D+ +P  D
Sbjct: 238 DSVGGWLGGQLGRIPRRGDSAAHGDLLIEVIRADARRALWLRAKRTSDAAKPGSD 292


>UniRef50_UPI000050F785 CBS domain-containing protein n=1 Tax=Brevibacterium linens BL2
           RepID=UPI000050F785
          Length = 417

 Score =  289 bits (742), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 87/283 (30%), Positives = 150/283 (53%), Gaps = 11/283 (3%)

Query: 12  ISNKKGFFSLLLSQL------FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIA 65
           +        LL + L        G     D+L  L+  + ++D+I++  R+M++ V +++
Sbjct: 136 LKPLTKILVLLGNLLTPDRVYKDGPFVTSDQLRDLVERASESDVIEDGEREMIQSVFNLS 195

Query: 66  DQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF 125
           D    ++M+PR+ ++T+     L + +++   S  SR PV  ED D I G+   KD+   
Sbjct: 196 DTSANEVMVPRTDLVTVNSGTPLSKVMNLFFRSGFSRIPVSGEDLDDIRGVAYLKDVARR 255

Query: 126 MRSDAEA--FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIED 183
           +    E     +D + R  + VPE+K  D ++++ +    H+AI+IDE+GG +GLVTIED
Sbjct: 256 LHLHPEDAERPVDILARGVLFVPETKPADDLMEQMQVDSTHLAILIDEYGGTAGLVTIED 315

Query: 184 ILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLV 243
           I+E IVGEIEDEYD  DD +  ++   ++ V    SI DF + F     +++V+++GGL+
Sbjct: 316 IVEEIVGEIEDEYDTSDD-ELVEVDDGSFVVSTRMSISDFADYFDVKIDEDDVNSVGGLL 374

Query: 244 MQAFGHLPARGETIDIDGYQFKVAMADSR--RIIQVHVKIPDD 284
            +  G +P  G    I+G   +      R  RI  V V   ++
Sbjct: 375 TKLIGRVPIDGSNARIEGLIIEAMEGQGRRHRITHVRVTKEEN 417


>UniRef50_UPI000196CD6F hypothetical protein CATMIT_02806 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196CD6F
          Length = 427

 Score =  289 bits (741), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 81/270 (30%), Positives = 151/270 (55%), Gaps = 2/270 (0%)

Query: 13  SNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +   G   +L   +      + ++L  ++  S +  +++++ ++M+  + D  D  +++I
Sbjct: 147 AVSHGLIHILGGNIDPQPTLSEEDLKTIVNVSHEEGVLEDEEKEMMHNIFDFGDTDIKEI 206

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR  + T+  + T DE + V+ ES +SR PV+SE+ D I G+L  KD+L     D E 
Sbjct: 207 MTPRIHVATVDYDATYDEVVAVLQESQYSRLPVLSEEGDEIVGVLHIKDILMKPV-DHEH 265

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
           F +   +R A  V E   +  +    R +   +++V+DE+G ++G+VT+EDI+E IVGEI
Sbjct: 266 FQVKDYMRDAYFVYEFNHISDVFASMRKEHVSLSVVLDEYGVMAGIVTLEDIVEEIVGEI 325

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
           +DEYD+  + + +++S++ + V    +I++ N+  GT F+ EE ++IGGLV+      P 
Sbjct: 326 DDEYDDNSE-EVKKISKNVYLVDGSLNIDEVNDRCGTEFASEEFESIGGLVLGQVNGSPN 384

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
             + + +D   F +   D  RI  + + IP
Sbjct: 385 PHQKVYVDDCMFIIEKIDKNRIELLRLIIP 414


>UniRef50_A6CIW3 Probable hemolysin n=2 Tax=Bacillus RepID=A6CIW3_9BACI
          Length = 445

 Score =  289 bits (741), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 76/282 (26%), Positives = 142/282 (50%), Gaps = 6/282 (2%)

Query: 14  NKKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +      L         E    +++  ++    +   I+   + M+  + +  D+   DI
Sbjct: 160 SSNTVIRLFGIDPNEQNEEATEEDIRMMVDIGRERGTINTVEKVMINNIFEFNDKIASDI 219

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           +  R+ M  L  +  L+E L+++ +  ++RFPV  + +D+I G+L +KDL  ++  D E 
Sbjct: 220 ITHRTDMCVLSIDADLEEVLEMVSKEGYTRFPVYEKVRDNIVGVLHSKDLFQYIGKD-ED 278

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
           F +  V+R+   V ES+ +D +    ++   H+AIV+DEFGG  G++TIED++E IVGEI
Sbjct: 279 FDLRNVIRKPYFVLESQTIDVLFTTMQTNNVHIAIVLDEFGGTEGMITIEDVIEEIVGEI 338

Query: 193 ED--EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
                 +   + + +Q+S + + V+ +A + +       HFS EE+DT+ G ++   G+ 
Sbjct: 339 YSESIEEGIYEEEIKQISPNQYEVKGIARLWELEAVLKVHFSTEELDTLSGFLIHELGYF 398

Query: 251 PARGET--IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           P+  E   ID    QF+V      R+ +  V +  D    + 
Sbjct: 399 PSVQERPVIDYKHLQFEVLEIKDNRVEKAMVTVKTDDLSKEA 440


>UniRef50_A0JX40 CBS domain containing protein n=4 Tax=Micrococcaceae
           RepID=A0JX40_ARTS2
          Length = 447

 Score =  289 bits (741), Expect = 9e-77,   Method: Composition-based stats.
 Identities = 87/275 (31%), Positives = 153/275 (55%), Gaps = 6/275 (2%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
            ++       + +E   L+  + ++D+I+++  ++++ V D  D  VR +M+PR+ ++++
Sbjct: 153 GARAGDEASFSEEEFRELVDRATESDMIEDNEAELIQSVFDFGDTLVRAVMVPRTDILSI 212

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL---LPFMRSDAEAFSMDKVL 139
               +L   + + + S +SR PVI ++ D I GI+  KD+   L  +    E   +D + 
Sbjct: 213 DAGSSLHRAMSLFLRSGYSRIPVIRDNTDQILGIIYLKDVAAALHGLGPGEEPPIVDDLA 272

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
           R+   VPESK+V  +L+E + +  H+AIVIDE+GG +GLVT+ED++E IVGEI DEYD  
Sbjct: 273 REVRYVPESKQVSDLLRELQKESTHVAIVIDEYGGTAGLVTLEDLIEEIVGEIVDEYDT- 331

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
           +  +   L   ++ V A   I+D  E F     D+EVDT+GGL+ +A G +P  G T+++
Sbjct: 332 ESAEAVALGNGSYRVSARMGIDDLGELFDVELDDDEVDTVGGLLAKALGRVPIVGSTVEV 391

Query: 260 DGYQFKVAMADSR--RIIQVHVKIPDDSPQPKLDE 292
           DG   +    + R  R+  +          P+  +
Sbjct: 392 DGISLRAERLEGRRNRVSHIIAAPVAKGAVPEQTD 426


>UniRef50_A7VVN2 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VVN2_9CLOT
          Length = 431

 Score =  289 bits (741), Expect = 9e-77,   Method: Composition-based stats.
 Identities = 66/270 (24%), Positives = 131/270 (48%), Gaps = 4/270 (1%)

Query: 24  SQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLK 83
            +          EL  ++       ++++   ++++  ++  ++ V++++ PR  M TL 
Sbjct: 156 IKEEETPIVTEQELKFIVESIEDEGVLEKQESELVQHALEFDEKTVQEVLTPRVDMTTLD 215

Query: 84  RNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAV 143
               L   + +++    SR PV     D I GIL  KDLL  +    +A  +  +++ A 
Sbjct: 216 IEDDLQTNIGLVLTERFSRIPVCRGTSDRIIGILHTKDLLEALVRG-DAIDLASMVQPAF 274

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
            V ++K++  +L +F+  + H+AIV D++GG  G+VT+ED+LE +VG+I DE DEE   D
Sbjct: 275 FVYKTKKLSSLLADFKRNKTHVAIVTDDYGGTVGMVTMEDLLEELVGDIWDE-DEEIIRD 333

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFS--DEEVDTIGGLVMQAFGHLPARGETIDIDG 261
           F ++    + +    +I +  +     FS  +    + GG  ++A GH+P  GE      
Sbjct: 334 FVRIDSQHFLISGDLTIRELFDHLDLPFSNLESNHTSCGGWALEALGHIPQAGEAFQFKN 393

Query: 262 YQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
               +   D +R+ ++ V +     + +  
Sbjct: 394 MTLTIQEMDDQRVKKLSVYLAPQPEEEEKS 423


>UniRef50_C4ZBH2 Hemolysin n=1 Tax=Eubacterium rectale ATCC 33656 RepID=C4ZBH2_EUBR3
          Length = 303

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 74/267 (27%), Positives = 140/267 (52%), Gaps = 7/267 (2%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
             +    +E+++++R+  +   I     +++  V +  D+ V+DIM  R  +++L  + +
Sbjct: 38  GNDDVTEEEIISMVREGHEQGTILASEAELIHNVFEFDDKEVKDIMTHRKNIVSLDGSMS 97

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA----EAFSMDKVLRQAV 143
             + ++ II++  SRFPV   D D I G+L  KD   F   +         +D ++R   
Sbjct: 98  FIDAIEFIIDTGKSRFPVYENDVDSIIGVLHIKDAFTFFEKNEVYRSSIKDIDGLIRPVD 157

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
            +PE+  ++ + K+ +S++ H+A+V+DE+G +SGL+ +EDILE +VG IEDE+DEE++  
Sbjct: 158 FIPETVNINDLFKKMQSKKSHLAMVVDEYGQISGLIAMEDILEELVGNIEDEHDEEEN-Y 216

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID--G 261
            R+    T+ +  +    D  EA      D+  +T+ G ++     +P  G+   I   G
Sbjct: 217 IRKNDDETFIMDGMTEFSDVKEALSLPVDDDAYETLNGFIISLSDKIPEEGDKTVISAYG 276

Query: 262 YQFKVAMADSRRIIQVHVKIPDDSPQP 288
           Y+F V   + + I QV +K      + 
Sbjct: 277 YRFSVMSVEDKVIKQVMIKKLAPEEKK 303


>UniRef50_Q01WS1 Putative uncharacterized protein n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01WS1_SOLUE
          Length = 446

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 85/267 (31%), Positives = 140/267 (52%), Gaps = 13/267 (4%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
           HG     +EL  ++  S     + E   DM+  V+D+    VR+IMIPR+ ++++  + +
Sbjct: 178 HGNVHTSEELKLIVSSSRGLGYLPETQEDMIHRVLDLGALSVREIMIPRNDIVSISTDAS 237

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA---------EAFSMDKV 138
           LDE L  + E  HSR PV  +  + I G+L  KDLLP               ++F + ++
Sbjct: 238 LDEVLHTMNEQRHSRLPVYEKTPEKIVGLLHYKDLLPVWEERRLAIRSSRPSQSFRVSRL 297

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +R  + VPE+K V  ML EFR  R HMA+++DEFG + G+VT+ED+LE IVG+IEDE+DE
Sbjct: 298 MRPLMFVPETKEVSAMLDEFRHGRSHMAMIVDEFGTIIGMVTVEDVLEQIVGQIEDEHDE 357

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETI 257
             +   RQ+      +     I D    +G     +   +T+ G ++   G +P     +
Sbjct: 358 RVE---RQVEADDVELDGTTRIRDLESEYGIEIPPDAGFETLAGFLLFKLGEIPRVESRV 414

Query: 258 DIDGYQFKVAMADSRRIIQVHVKIPDD 284
           + +G ++ V   +  RI +V ++    
Sbjct: 415 EYEGRRYTVLEMERNRIARVRIEKLQP 441


>UniRef50_UPI0001973384 hypothetical protein ClM62_01605 n=1 Tax=Clostridium sp. M62/1
           RepID=UPI0001973384
          Length = 470

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 89/291 (30%), Positives = 143/291 (49%), Gaps = 13/291 (4%)

Query: 14  NKKGFFSLLLSQ-LFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +      LL  +     E    +++  +I    +   I ED  + ++ V D  D  +   
Sbjct: 165 STNLVLRLLGMKTEAEEEGVTEEDIRMMIDLGKEKGTIAEDENEWIQNVFDFRDTSILSA 224

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M   S ++ L  + +  E L +I ES  SR PV ++D + ++GIL  ++ L  + +  + 
Sbjct: 225 MTRESDIVNLFEDSSEQEILKIIRESGLSRLPVYTKDHEDVKGILYTREYLLNLTA-KQP 283

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
            S+ ++L QA  VPES   D + ++ ++++ HMAIV+DE+G +SGL+T+ED+LE IVG I
Sbjct: 284 KSLSQLLHQAYFVPESIHADDLFRDMQTKKVHMAIVVDEYGNISGLITMEDLLEEIVGSI 343

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLP 251
            DE+D   D +  ++S + W       IED  E       D EE DTIGG+V+     +P
Sbjct: 344 YDEFDRVIDPEIERISENLWRFPGDTLIEDVEEQMDITLPDQEEYDTIGGMVLSCLHTIP 403

Query: 252 ARGET--IDIDGYQFKVAMADSRRIIQVHVKIPDDS--------PQPKLDE 292
             G T  ++I+G          RRI  V VK  D             + DE
Sbjct: 404 KDGTTVDVEINGLSLHAEKIVGRRIESVLVKKLDTEQSSSAPTGESEEQDE 454


>UniRef50_C7LQH5 Putative uncharacterized protein n=1 Tax=Desulfomicrobium baculatum
           DSM 4028 RepID=C7LQH5_DESBD
          Length = 433

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 91/277 (32%), Positives = 136/277 (49%), Gaps = 7/277 (2%)

Query: 13  SNKKGFFSLLLSQLF--HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
            +      LL       HG     DEL  LI  S  +  I+E+ R ++    D       
Sbjct: 159 WSGTRTVRLLGFTPSATHGSVYTEDELRMLIDASYSSGQIEEEKRRLIRRAFDFNTTEAC 218

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           + MIPRS++  L    TLDE LD      +SR PV  ED D + G+L  +D+ PFM  + 
Sbjct: 219 EAMIPRSEIAALPVTSTLDEVLDAFRIHGYSRLPVYGEDLDDVVGVLFRQDMEPFMAREP 278

Query: 131 EA-FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
              FSM  +L     VP  KR+  +LK+ ++ R H+  V+DE+GG+ GLVT+ED+LE IV
Sbjct: 279 GLVFSMTGLLHPPTFVPSGKRLGSLLKQMQATRTHLIFVMDEYGGLEGLVTLEDVLEEIV 338

Query: 190 GEIEDEYDEEDDIDFRQLSRHT-WTVRALASIEDFNEAFGTHFSDEE-VDTIGGLVMQAF 247
           GEI DEYDEE      +    T + +  + ++ D N   G    ++E   T+ G ++   
Sbjct: 339 GEINDEYDEEVRSQIVR--DGTAFILDGMLAVRDLNRKLGLKLPEDEAYTTVAGFLLSEA 396

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           G +   G+ + I    FKV   + RRI+++       
Sbjct: 397 GRVLEAGDEVPIKEGVFKVERLERRRIVRIRFTPEAH 433


>UniRef50_Q1IKR3 CBS domain protein n=1 Tax=Candidatus Koribacter versatilis
           Ellin345 RepID=Q1IKR3_ACIBL
          Length = 422

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 83/276 (30%), Positives = 147/276 (53%), Gaps = 6/276 (2%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
                +L             + + ALI    +  +++E  R +++ V++  D+ VR++M 
Sbjct: 148 TISVAALAKENAEEEPEHPSEAVDALIEAGTEEGILEESDRHLIQSVVEFGDKTVREVMT 207

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR ++  +  + TL++  D + +  +SR PV     D++ GI+ ++DLL    +DA    
Sbjct: 208 PRPRIFAVPTDWTLEQLTDALRDQGYSRIPVFRGSIDNLVGIVFSRDLLQIADTDARTRK 267

Query: 135 MDKVLR-QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
           +  ++R + + VPE+KR   +L+E +     MA+VIDE+G V+GLVTIED++E IVGE+ 
Sbjct: 268 VGDLVREELMFVPETKRGSELLREMQRDNVRMAVVIDEYGSVAGLVTIEDLIEEIVGELR 327

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPA 252
           DE    D+ D  +   HT+ V     ++  NE FG    ++ E  T+ GLV +  G +P 
Sbjct: 328 DE----DETDIVKEGEHTYVVPGSMDVDRLNELFGVRVDEDHESSTVAGLVSEIAGRIPQ 383

Query: 253 RGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
            GE ++  G +F+V  +  RRI ++ +     +P  
Sbjct: 384 PGEVVENLGLRFEVLASTDRRIERLRISEATQTPDQ 419


>UniRef50_C7RN87 Putative uncharacterized protein n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RN87_9PROT
          Length = 480

 Score =  288 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 80/280 (28%), Positives = 138/280 (49%), Gaps = 14/280 (5%)

Query: 14  NKKGFFSLLLSQLFHGE-----PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
           +  G   +   +   G        + +E+  ++  S ++  +D +   M+ GV  + +  
Sbjct: 170 SSNGLLWIFGQKDLRGHGESHFTMSVEEIRMILSASEKDGTLDPEETQMIRGVFKLDEHT 229

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-- 126
           VR+ M+PR+++  L +  TL + L V  +  H+RFPV  +  D I G++  K+LL  M  
Sbjct: 230 VREAMVPRTRIRALTQEDTLADALRVFRDVPHARFPVCDKSLDRITGVVAIKELLTVMAE 289

Query: 127 -----RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181
                  +     + +  +   +VP SK +  +LKEF+  R  MAIVIDE+GG  G++T+
Sbjct: 290 SSGQTLEEVSRRPVGEFAQAPFIVPNSKSLSDLLKEFKHTRQQMAIVIDEYGGTEGIITL 349

Query: 182 EDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIG 240
           EDILE IVGE EDE+        ++L    + + A   + D        F  D++  T+ 
Sbjct: 350 EDILEEIVGEYEDEF-TRQARRVKKLVGSQYEIDASMRVSDLETLIDFPFPTDDDYVTLA 408

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
           GL  +  G +P  G+T+ ++G Q  V   D+ RI  +  +
Sbjct: 409 GLFYKKLGSVPKVGDTVKLEGGQLTVLEMDNHRITLLRFE 448


>UniRef50_Q8YM44 All5096 protein n=16 Tax=Cyanobacteria RepID=Q8YM44_ANASP
          Length = 436

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 70/275 (25%), Positives = 128/275 (46%), Gaps = 7/275 (2%)

Query: 14  NKKGFFSLLLSQLFHG---EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVR 70
           +      L   +        P   +EL  +I    ++  ++   R++L  + +  D   +
Sbjct: 162 STSYLLRLFGVEYTGQSWRPPVTPEELQLIISTERESTGLEMAERELLNNIFEFGDVTAQ 221

Query: 71  DIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA 130
           D+MIPR+ +I L ++      L  +  + HSR+PVI E  D I GI+  +DL   +    
Sbjct: 222 DVMIPRNGIIALSKDANFQNLLQQMTATGHSRYPVIGESLDDIRGIVYFRDLANPLAIGK 281

Query: 131 EAFS--MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
            +    +   +R    VPE   +  +L   + ++  M IV+DEFGG  GLVTI+D++  I
Sbjct: 282 LSLETQIQPWMRPVRFVPEHTPLSELLPMMQQEKPAMVIVVDEFGGTVGLVTIQDVIAEI 341

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAF 247
           +G    E    +D+  + L + T+ V+A  ++ED NE    +     +  T+ G ++   
Sbjct: 342 IGN-AGETSSSEDLLIQMLDQETFLVQAQVNLEDLNEVLHLNLPLTRQYQTLAGFLLYQL 400

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
             +P +GE    D  +F +   D  R+ Q+ ++  
Sbjct: 401 QKMPIKGEIFCYDNIEFTIVSVDGPRLHQIQLRRL 435


>UniRef50_C9RLZ8 CBS domain containing protein n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RLZ8_FIBSS
          Length = 441

 Score =  287 bits (736), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 83/251 (33%), Positives = 134/251 (53%), Gaps = 4/251 (1%)

Query: 45  GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFP 104
            + + ++++ R M+  + D  +  VR+IM PR  M  +  + +L++ + V+    HSR P
Sbjct: 186 SEGEGLEKEERQMILNIFDFVETPVREIMTPRVDMCAIDVDTSLEDLVKVLNNERHSRLP 245

Query: 105 VISEDKDHIEGILMAKDLLPFMRSD-AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRY 163
           V  E  D+I GIL  +D L +      E F + K++   V VP  K++D +L E R    
Sbjct: 246 VYKETVDNIVGILSNRDFLEWYTEHHEEPFDLMKLVMPPVYVPYHKKIDDLLTELRKTGN 305

Query: 164 HMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDF 223
            +AIV+DE+GG +GLVT+EDILE IVGEI DE D ++D D ++L    + +  L ++ D 
Sbjct: 306 QLAIVVDEYGGTAGLVTLEDILEEIVGEIRDEDDMDEDEDVQKLKDGRYILDPLMTLSDL 365

Query: 224 NEAFGTHF---SDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
                       +  V+T+ GL+    G +P+ G  + I GY F+V   D  R+ +V + 
Sbjct: 366 EYELDVELKPPENSHVETLSGLIQATLGIIPSPGAEVKIQGYTFRVLRMDGTRMEKVMMI 425

Query: 281 IPDDSPQPKLD 291
           +P     PK  
Sbjct: 426 LPAGVKGPKTQ 436


>UniRef50_A4J4V5 Putative uncharacterized protein n=1 Tax=Desulfotomaculum reducens
           MI-1 RepID=A4J4V5_DESRM
          Length = 445

 Score =  287 bits (736), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 84/273 (30%), Positives = 142/273 (52%), Gaps = 7/273 (2%)

Query: 14  NKKGFFSLLLSQLF--HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           + +    L+  Q+   H +  + +E+  ++  S +   I +    +    +  AD+   +
Sbjct: 159 SARYIIKLIGLQVVSEHHQIHSEEEIRMILLQSHKGGEITQTELQLARNSLHFADRVAAE 218

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM+PR  M+ L  N + +E L +I E  ++R+PV   DKD+I G +  KDL     +D  
Sbjct: 219 IMVPRPDMVCLYTNLSWEENLKIITEEKYARYPVCDGDKDYIIGFVNTKDLCFSGLTDLN 278

Query: 132 AFSMDKV----LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
             +++      LR+A+VV E   +D +LK+ +  R  MAIV DE+GG +GL+T+EDILE 
Sbjct: 279 MLNLEGFLKQALRKAMVVTELTPIDEILKKMQKNRLQMAIVQDEYGGTAGLLTLEDILEE 338

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           IVGEI+DE+DEE  +    L  + +++ A   I DFN  F      + V T+ G   +  
Sbjct: 339 IVGEIQDEHDEERQL-IESLGGNRYSLDARLPIADFNLEFDLDLKAKGVYTLAGWFQEES 397

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
              P +G+T+     QF ++  D   I ++ + 
Sbjct: 398 HRTPEKGQTVRYKNLQFSISEIDKNTIRRIEMT 430


>UniRef50_A9NGP1 Putative hemolysin-related protein n=2 Tax=Bacteria
           RepID=A9NGP1_ACHLI
          Length = 422

 Score =  287 bits (736), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 77/263 (29%), Positives = 146/263 (55%), Gaps = 5/263 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           + +       + DEL+ ++ +  ++  IDE +  ++   ++ AD    DI  PR  ++ +
Sbjct: 154 IVKPNSKAHLSEDELIMIVDEVQESGAIDESSGTLIRSAIEFADLEAVDIYTPRIDVVAV 213

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQA 142
                 ++   V  ES +SR PV  E+ DHI G++  KD    +      F + ++++  
Sbjct: 214 STAARHEDIFKVFKESGYSRIPVYEENIDHIIGVMNYKDFFMVLTEG---FDIKEIIKDV 270

Query: 143 VVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDI 202
           + +P++K+V  +L E +  + HMA+VID++GG +G++T+EDILE +VG+I DE+D+  + 
Sbjct: 271 LFIPKTKKVKDLLLELQQSKSHMAVVIDDYGGTAGILTLEDILEELVGDIWDEHDDIIEA 330

Query: 203 DFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGY 262
             ++++ + + V   +SIEDF E  G+   +  V T+ G V++  G LP  G+T ++  Y
Sbjct: 331 -VKKMNDNQYLVLGNSSIEDFLEIIGSK-EEPNVLTVNGWVVEKLGTLPVEGKTYEVKPY 388

Query: 263 QFKVAMADSRRIIQVHVKIPDDS 285
            F++   D +RI  V + I  + 
Sbjct: 389 TFEIVKMDGKRIDLVQITIEKEE 411


>UniRef50_B3WFB2 Transport protein n=8 Tax=Lactobacillus RepID=B3WFB2_LACCB
          Length = 448

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 94/289 (32%), Positives = 152/289 (52%), Gaps = 8/289 (2%)

Query: 11  TISNKKGFFSLLLSQLFH--GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
            +S        L    F+  GE   RDE++++I     +  ID D   M EG++ ++D  
Sbjct: 158 LLSASTKLLMKLTPMEFNHEGETVTRDEMVSMIESGRNSGAIDPDEYQMFEGIISLSDTM 217

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS 128
            R++M+PR+    +   +     +D I+ + +SR PV  EDKDH+ GI+  K+LL   R 
Sbjct: 218 AREVMVPRTDAFMVDAQEPDHTAIDAILNNIYSRIPVYEEDKDHVVGIVHIKNLLKEARR 277

Query: 129 -DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
              +   ++ V+   V VPE+  VD +L E + ++  MAI++DE+GGV G+VTIED+LE 
Sbjct: 278 VGFDHVKIESVMTAPVFVPETITVDDLLTEMQVKQQQMAILLDEYGGVVGIVTIEDLLEE 337

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           IVGEI+DE D+ + + F +   H + V     I DFN+ F T     +VDTI G V+   
Sbjct: 338 IVGEIDDESDQVEKL-FTKQGDHDFVVSGRMPISDFNDLFKTDLDAPDVDTIAGYVLTQL 396

Query: 248 GHLPARG--ETIDI-DGYQFKVAMADSRRIIQVHVKIPDDS-PQPKLDE 292
           G +P+    E + +  G        +  R++ VH+ +  +  P+    E
Sbjct: 397 GAIPSSHHSEKMQLAPGVLLATGKVEGSRLVNVHIHLSSEPVPEEASHE 445


>UniRef50_D0MK91 CBS domain containing protein n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MK91_RHOM4
          Length = 416

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 84/269 (31%), Positives = 137/269 (50%), Gaps = 13/269 (4%)

Query: 20  SLLLSQLFHGEPKNRDELLALIRDSGQNDL----IDEDTRDMLEGVMDIADQRVRDIMIP 75
             L  +        + EL   +++          +DE    +L   +     RVRD M+P
Sbjct: 155 RRLSVEADTVATFMQQELAWQVQEVEAETAPARDLDETESRLLANALAFEKLRVRDCMVP 214

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R+ ++ ++ +  L+      IES +SR PV  E  D I G++ A DL        +  S+
Sbjct: 215 RTDIVAVEEHTDLETLRQRFIESGYSRLPVYREHIDQIIGVVFAYDLFR------QPSSL 268

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
            +++R    VPESK    +LKEF      +AIVIDE+GG +GLVT ED+LE ++G+I+DE
Sbjct: 269 AEMIRPVRFVPESKPAHALLKEFLQTNTSIAIVIDEYGGTAGLVTQEDLLEELIGDIQDE 328

Query: 196 YDEEDDIDF--RQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           +D ++D ++  R+L   TW V     I++  EA G    + + DT+ G +++  G +P  
Sbjct: 329 FDVDEDEEYLLRRLDERTWLVSGRVDIDELREA-GLDLPEGDYDTVAGYLLEKLGTIPKP 387

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIP 282
            E  ++DGY+F +  A   RI  V +   
Sbjct: 388 QEEFELDGYRFTILKASQNRIELVRITRL 416


>UniRef50_C4GJN3 Putative uncharacterized protein n=1 Tax=Kingella oralis ATCC 51147
           RepID=C4GJN3_9NEIS
          Length = 289

 Score =  286 bits (734), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 125/291 (42%), Positives = 173/291 (59%), Gaps = 10/291 (3%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFH--GEPKNRDELLALIRDSGQNDLIDEDTRDML 58
           M D       T+      F+ L  ++    G P+   + L L+  +   + +D+DT   L
Sbjct: 1   MDDTTPQPKPTL------FNRLFHRVSGSIGIPETPAQWLDLLHQAQAQNSLDDDTLLRL 54

Query: 59  EGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILM 118
           E +       VRD M+ R+QM  +K    +D  +   +++AHSRFPVI EDKDHI GIL 
Sbjct: 55  ENLFKFNQLSVRDAMMTRAQMDVIKTTDGIDRIIAYAVDTAHSRFPVIEEDKDHIIGILH 114

Query: 119 AKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           AKDLL     + E F ++ +LR AV VPESK ++ +LK+F++QR HMAIV+DE+GG+SGL
Sbjct: 115 AKDLLKCTL-NPEQFKLEHILRPAVFVPESKSLNSLLKDFQTQRNHMAIVVDEYGGISGL 173

Query: 179 VTIEDILELIVGEIEDEYDEEDDID-FRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVD 237
           VT ED++E IVG+IEDE+DE+D  D    +S   W ++A   I   NE FGT FSDEE D
Sbjct: 174 VTFEDVIEQIVGKIEDEFDEDDSADNIFPVSAERWRIKATTEIAAINEYFGTDFSDEEAD 233

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           TIGGLV+   GHLP RGE + +    F VA AD+RR+  +    P    + 
Sbjct: 234 TIGGLVIHELGHLPVRGEKVQLGDLLFNVARADNRRLHTLMATRPGQKTET 284


>UniRef50_C6NUU3 Magnesium and cobalt efflux protein CorC n=1 Tax=Acidithiobacillus
           caldus ATCC 51756 RepID=C6NUU3_9GAMM
          Length = 292

 Score =  286 bits (734), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 111/285 (38%), Positives = 180/285 (63%), Gaps = 5/285 (1%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           MS+D S    +    + +++   +Q   G  +++D LL LIR++G+  +ID +   M++G
Sbjct: 1   MSEDRSSPERS----RSWWARF-TQSLRGNVEDQDTLLDLIREAGERQVIDAEAARMVDG 55

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           +  + +  VRD+MIPR+QM  ++ +  + E +  ++E  HSRFPV+  D+D + GIL+AK
Sbjct: 56  IFRMGELSVRDVMIPRAQMEVIELDLPIPEIIARVVEVGHSRFPVVGNDRDDVRGILLAK 115

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL       E   + ++LR A  +PESK +D +L EFR+ R+HMA+V+DE+GGV+GL+T
Sbjct: 116 DLLRACGQGQEPPRLTELLRPATFIPESKHLDHLLYEFRTGRHHMALVVDEYGGVAGLIT 175

Query: 181 IEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG 240
           IED+LE+IVGEIEDEYD E+D+         + V A+ ++ +FN  F T+  DE  DT+G
Sbjct: 176 IEDVLEIIVGEIEDEYDIEEDVMVVPREDGDFLVNAVITLPEFNTQFHTNLDDEYADTLG 235

Query: 241 GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           G +    GH+P  GE + +DG + +V  AD +R+  + + +P  +
Sbjct: 236 GWLSNRLGHVPRVGEVVMVDGLRLEVLRADRKRVQILRLSLPRAA 280


>UniRef50_Q9LG18 F14J16.20 n=17 Tax=Magnoliophyta RepID=Q9LG18_ARATH
          Length = 930

 Score =  286 bits (733), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 83/309 (26%), Positives = 154/309 (49%), Gaps = 36/309 (11%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
             G   +L  +         DEL  ++R +  +  I+E+ +DM+E V++I D  VR++M 
Sbjct: 573 SMGILKILGLKGRSEPYVTEDELKLMLRGAELSGAIEEEEQDMIENVLEIKDTHVREVMT 632

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--EA 132
           P   ++ +  + +L +  +  +   +SR PV  +  D+I GI  A DLL ++      E+
Sbjct: 633 PLVDVVAIDGSGSLVDFHNFWVTHQYSRVPVFEQRIDNIVGIAYAMDLLDYVPKGKLLES 692

Query: 133 FSMDKVLR-QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            ++  +    A  VP+S  V  +L+EFR ++ HMA+V++E+GG  G+VT+ED++E IVGE
Sbjct: 693 TTVVDMAHKPAFFVPDSMSVWNLLREFRIRKVHMAVVLNEYGGTIGIVTLEDVVEEIVGE 752

Query: 192 IEDEYDEEDDID-----FRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQ 245
           I DE D +++I          +   + V A  SI+  +E      ++  + +T+ G V +
Sbjct: 753 IFDENDSKEEIQKKTGYIVMRAEGIYDVDANTSIDQLSEELNIKMAEGHQYETVSGFVCE 812

Query: 246 AFGHLPARGETIDI--------------DG-------------YQFKVAMADSRRIIQVH 278
           AFG++P  GE++ +              +G             Y+ ++   ++R++  V 
Sbjct: 813 AFGYIPKTGESVTVVLEKENWEENDEQDEGKHERQDQKEKHQIYRLEILAGNARKVSAVR 872

Query: 279 VKIPDDSPQ 287
            +   D  Q
Sbjct: 873 FERVSDMDQ 881


>UniRef50_C6HVJ5 Putative uncharacterized protein n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HVJ5_9BACT
          Length = 460

 Score =  286 bits (733), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 83/247 (33%), Positives = 137/247 (55%), Gaps = 3/247 (1%)

Query: 47  NDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVI 106
           + +I+   +D+++ V    D  VR++M+PR +M+TL+   TL E + +  E+ +SR+PV+
Sbjct: 197 HGIINRTEQDLIQSVFKFTDISVREVMVPRVRMVTLRTGMTLSEIIGIFSENRYSRYPVL 256

Query: 107 SEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMA 166
             + + + GIL  KDL+  + +    F +DKVL     VPES +V  +LKE + +R  MA
Sbjct: 257 RAEGEEVAGILYYKDLVELLNA-PGTFRIDKVLHTPYFVPESMKVPYVLKEMQKRRTQMA 315

Query: 167 IVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEA 226
           +V+DE+G + GLVT+ED+LE IVGEIEDE DE       +L   ++ V A  SI D +E 
Sbjct: 316 LVLDEYGALDGLVTMEDLLEEIVGEIEDESDEVAKP-VERLRDGSYLVDASLSIRDLSED 374

Query: 227 FGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
           +     + E+ +T+ G V+     +P  GE       +  V   D +R+ +V ++  D  
Sbjct: 375 YRIPIPEGEDYETLAGFVLSQLQTIPRGGEFFFSKNMKVTVVEVDRQRVSRVRIEFLDAP 434

Query: 286 PQPKLDE 292
                 +
Sbjct: 435 ASSGTPD 441


>UniRef50_D2NSB8 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NSB8_9MICC
          Length = 444

 Score =  286 bits (733), Expect = 7e-76,   Method: Composition-based stats.
 Identities = 63/281 (22%), Positives = 127/281 (45%), Gaps = 4/281 (1%)

Query: 14  NKKGFFSLLLSQLFHG--EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +          +        +  +EL +++R S +   +D D    ++  +  ++    +
Sbjct: 159 SANWILGRFGMEAKEELSAARTPEELSSMVRRSAEEGTLDSDAARFVDRTLRFSELTASE 218

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           +M PR Q+  L+    + E + +   + HSRFP+   D D+I G++  K  +       E
Sbjct: 219 VMTPRGQVAMLEDTAPVAEVIKLARSTGHSRFPLYKGDHDNIVGVVHVKKAVGVPPEVRE 278

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
                 +    + VPE+  +D +L + R     +A+V+DE+GG +G+ T+ED++E IVGE
Sbjct: 279 TLEAGALAEDVLQVPETLHLDALLTQLRQGALQLAVVLDEYGGTAGIATLEDLVEEIVGE 338

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAF-GTHFSDE-EVDTIGGLVMQAFGH 249
           + DE+D        +     W    L   ++ N    G    +  E +T+GG +M+  G 
Sbjct: 339 VSDEHDRGRTERPLRYGNGDWVFSGLRRPDEINALIPGLEVEESPEYETVGGFMMERLGR 398

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           +P  G+++ + G   +V   + RR+ ++       + +   
Sbjct: 399 IPEVGDSVPVPGGTLRVDTLEGRRVDRIRFTPAPSAQEQTE 439


>UniRef50_A6LDG3 Hemolysin-related protein n=23 Tax=Bacteroidales RepID=A6LDG3_PARD8
          Length = 450

 Score =  286 bits (733), Expect = 7e-76,   Method: Composition-based stats.
 Identities = 98/258 (37%), Positives = 150/258 (58%), Gaps = 10/258 (3%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
            + DEL   +  +        + ++ML  ++   ++   +IM PR  M  ++   +  E 
Sbjct: 186 ISVDELSKALELTSTE---IPEEKEMLAEIIKFYNKTADEIMTPRLDMEDIEIKISFREV 242

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           +D II+S +SR PV SE +D+I+GIL  KDLLP++    + F    ++R A  VPE+K++
Sbjct: 243 VDFIIKSGYSRIPVYSETEDNIKGILYIKDLLPYIDK-PDTFRWQSLIRPAYFVPETKKI 301

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
           D +L+EFR+ + HMAIV+DEFGG SG+VT+EDILE IVGEI DEYDE++     +L+  +
Sbjct: 302 DDLLEEFRTNKIHMAIVVDEFGGTSGIVTMEDILEEIVGEISDEYDEDEQQFI-RLADGS 360

Query: 212 WTVRALASIEDFNEAFGTHFSD-----EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKV 266
               A   + DF        SD     EEV+T+ GL+++  G  P R E ID   Y+F+V
Sbjct: 361 LIFEAKILLTDFFRVIDADPSDFGKLTEEVETLAGLLLEIKGDFPRRREIIDFKEYRFQV 420

Query: 267 AMADSRRIIQVHVKIPDD 284
              D+RRI++V      +
Sbjct: 421 LEVDNRRILKVKFNRILE 438


>UniRef50_A9U7Q9 Predicted protein (Fragment) n=1 Tax=Physcomitrella patens subsp.
           patens RepID=A9U7Q9_PHYPA
          Length = 278

 Score =  286 bits (733), Expect = 7e-76,   Method: Composition-based stats.
 Identities = 73/263 (27%), Positives = 140/263 (53%), Gaps = 3/263 (1%)

Query: 29  GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTL 88
            +  + +EL  L+ +S ++  I+++    +  +    +   +DIM+PR+ M+ L   ++ 
Sbjct: 3   SDAHSEEELRILLSESLESGQINKNEYSFMNRIFTFDELLAKDIMVPRTDMVCLDATKSR 62

Query: 89  DECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPES 148
           +E L +I +  ++RFPVI ++KD+I G++  K L      +     +  ++R  + V E+
Sbjct: 63  EENLRIIRQEQYTRFPVIRQNKDNIIGVINTKALF-LAPDNQAGAPLASLVRPVMTVSEN 121

Query: 149 KRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLS 208
             +  +L + + +R H+A++IDE+GG SG+VTIEDILE IVG+I DE+D E++ +  +++
Sbjct: 122 IPLPALLTKMQKERTHIAVLIDEYGGTSGMVTIEDILEEIVGDIRDEFDAEEEQEITEVA 181

Query: 209 RHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
            +   V    S+   N+       +E+ DTIGG +      +   G  +     QF V  
Sbjct: 182 ANHLIVDGKVSVSLINDWLDAQLEEEDADTIGGWIYGQNLDI-EVGTQLVYGDLQFTVLE 240

Query: 269 ADSRRIIQVHVKIPDDSPQPKLD 291
            +  RI ++ ++   + P P   
Sbjct: 241 REDSRIRKIDIEKL-EPPAPGSS 262


>UniRef50_UPI0001C3727C hypothetical protein RflaF_01904 n=1 Tax=Ruminococcus flavefaciens
           FD-1 RepID=UPI0001C3727C
          Length = 440

 Score =  286 bits (733), Expect = 7e-76,   Method: Composition-based stats.
 Identities = 71/287 (24%), Positives = 130/287 (45%), Gaps = 7/287 (2%)

Query: 9   SDTISNKKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
           + T ++  G   L         E    +E+L +     +   ID+D   +++ V    D 
Sbjct: 155 AVTNASANGILRLFGIDPDSGAETVTEEEILMMSDAGAEKGTIDQDENRIIKNVFAFDDL 214

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
               +   R+ +  L      +   + I  + HS FPV  E  D++ G+L AKD      
Sbjct: 215 TAEQVCTHRTDVSVLWSKDDTEVWEETIHRTRHSVFPVCGESVDNVIGVLDAKDYFRLDD 274

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRY-HMAIVIDEFGGVSGLVTIEDILE 186
              +   M+  +R+ + V E+ + DR+ ++ +     H A+V+DE+GG+SG+VTI D++E
Sbjct: 275 KSRDNI-MENAVREPLFVHENMKADRLFEQMKQDGSDHFAVVVDEYGGMSGIVTITDLVE 333

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            +VG+  D+ ++E  +   Q     WTV  ++++ +  +        ++ DT GG V+  
Sbjct: 334 QLVGDFADDPEDEPAVKLTQTGDDEWTVPGISALTEVCDELDITLPADKYDTFGGYVIDR 393

Query: 247 FGHLPARGETIDID--GYQFKVAMADSRRII--QVHVKIPDDSPQPK 289
            GH+P  G  + +D  G    V      RI   +V V   D   + +
Sbjct: 394 LGHIPKNGTQVSLDTDGLHIDVTEVKHHRIEVCKVKVLSRDTEVEEE 440


>UniRef50_Q1K2A8 Putative uncharacterized protein n=1 Tax=Desulfuromonas acetoxidans
           DSM 684 RepID=Q1K2A8_DESAC
          Length = 461

 Score =  285 bits (732), Expect = 8e-76,   Method: Composition-based stats.
 Identities = 70/274 (25%), Positives = 123/274 (44%), Gaps = 6/274 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +  G   LL  +         +++LA++ +  Q  +I++    +   V  + D+    +M
Sbjct: 180 STDGVLRLLGKEGHTSATLTEEDILAILLEGSQTGVIEKQEHTLARNVFRLDDRLAVSLM 239

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PRS ++ L   +  ++ LD ++ S H+RFPV  E  D + G++ A  LL +        
Sbjct: 240 TPRSDIVYLDVARPFEQSLDALMSSPHTRFPVCREGMDEVLGVVNASRLLKYHLEGNLQK 299

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
                L  AV VPES    ++L+ F++    M  VIDE+G + GL+T++D+ E + GE  
Sbjct: 300 PTKSDLTPAVYVPESLTGMKLLQRFQTSGVQMVFVIDEYGAIVGLITLQDLFEALSGEFS 359

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFGH 249
               +  D+   +     W +  L  I +  +        DEE     T+GG++M   G 
Sbjct: 360 SS--DPHDVWAVRHKDGAWMLDGLIPIPELKDRLELKQVPDEEKRHYHTLGGMMMCLIGK 417

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPD 283
           +P  G+     G+  +V   D  RI +V      
Sbjct: 418 VPRSGDVAKWQGWSLQVTALDGNRIDKVRAVRLP 451


>UniRef50_Q0G3C6 Putative uncharacterized protein n=2 Tax=Aurantimonadaceae
           RepID=Q0G3C6_9RHIZ
          Length = 444

 Score =  285 bits (732), Expect = 9e-76,   Method: Composition-based stats.
 Identities = 82/275 (29%), Positives = 144/275 (52%), Gaps = 5/275 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           + K      +S+    E    +++ ++I++  Q  +  E  R+MLEGV+ IAD+ VR IM
Sbjct: 159 STKVVTKPFVSEDDKEEEVTEEDVRSMIKEGTQLGVFKEKEREMLEGVIRIADRNVRSIM 218

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           +PR  +  L  + + DE  + II + HSRFPV+  ++D I GI+  KDL    R +    
Sbjct: 219 VPRPDVDWLSVHDSEDENFEEIIRAGHSRFPVLDTEEDAIVGIVQTKDLFELQRREGR-M 277

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            +   +R+ + V E+  + ++L+ FR    H+A+V+DE+G   G+ T +DIL  I G + 
Sbjct: 278 DLKTAMRKPLYVNEAMPILKLLEAFRKANLHIAVVLDEYGSFEGIATPQDILTAIAGSLP 337

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG-THFSDE-EVDTIGGLVMQAFGHLP 251
            E  EED   FR+    +W V     ++ F        F ++ + +T+ G V++  GH+P
Sbjct: 338 -EGAEEDVSAFRRQ-DGSWLVDGAMPVDAFAYKLKTIEFPEDRDYETVAGFVLEQIGHIP 395

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSP 286
             GE  + + ++ +V   D +RI ++       +P
Sbjct: 396 GVGEIFEWENFRVEVVDLDGQRIDKLLFTEKAAAP 430


>UniRef50_A7HZ85 CBS domain containing protein n=1 Tax=Parvibaculum lavamentivorans
           DS-1 RepID=A7HZ85_PARL1
          Length = 319

 Score =  285 bits (732), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 91/283 (32%), Positives = 152/283 (53%), Gaps = 12/283 (4%)

Query: 17  GFFSLLLSQLFHGEPKNRDELLALIRDSGQ-NDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           G+   LL    +G+   R+ L  +I +    +  +  + R ML  ++   + RV D+M+P
Sbjct: 27  GWLRALLGLNGNGDGSLRESLEEVIEEHEDMHRSLTAEERHMLVNILKFGELRVDDVMVP 86

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE---- 131
           R+ +I ++ +  L+ECL +   S+HSR P+  E  D   G++  KD+L ++    E    
Sbjct: 87  RADVIGVEESCPLEECLRLFHVSSHSRMPIYRETLDDPIGMVHLKDVLAWLAPQEEEAPP 146

Query: 132 --AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
             AFS+  + R  + VP S     +L + ++ R H+A+VIDE+GG  GLV+IED++E IV
Sbjct: 147 RPAFSLRSIRRNILFVPPSMPALDLLVKMQATRIHLALVIDEYGGTDGLVSIEDLVEEIV 206

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF----SDEEVDTIGGLVMQ 245
           GEIEDE+D ++     +    T    A   IED  +  G        +++VDT+ GLV  
Sbjct: 207 GEIEDEHDTDEGPALVRREDGTIDADARCPIEDLEDMIGLRLVEEEHEDDVDTLAGLVFS 266

Query: 246 AFGHLPARGETIDID-GYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             G +P RGE +    G +F+V  AD+RRI ++ + +   + +
Sbjct: 267 LLGRVPLRGELVRHPAGLEFEVKDADARRIKRMRIHLLTAAEK 309


>UniRef50_A7VCA4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VCA4_9CLOT
          Length = 433

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 79/269 (29%), Positives = 144/269 (53%), Gaps = 1/269 (0%)

Query: 18  FFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRS 77
           F+ L +      +    DEL+ ++  S +  +I+   ++M+  V+D  D RVRDIMIPR+
Sbjct: 156 FWILHMDTNESAKSITEDELITMVNVSEEEGVIENKEKEMITNVVDFGDSRVRDIMIPRT 215

Query: 78  QMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF-MRSDAEAFSMD 136
            +  +    T DE L   +E  ++R PV  + +D++ GIL  KDL  +    D   F + 
Sbjct: 216 DVTMVPVTATYDELLKQYMEVPYTRLPVYKDSRDNVIGILHVKDLFFYKATHDINNFDVT 275

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
            ++R+   V E ++ + +L   +S    + IV+DE+G   GL+++ED++E I+G+I+DEY
Sbjct: 276 NIVREPFYVYEFQKTNDLLANMKSSSNSIGIVLDEYGVCVGLISMEDLIEEIIGDIKDEY 335

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
           D+ +  +  ++    +++     ++D N+A       E+ D+IGG ++Q   HLP+ G+T
Sbjct: 336 DDAEHNNIVKIDDTHYSIDGGIKLDDLNDALDLDIESEDYDSIGGYIIQLLDHLPSVGDT 395

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDS 285
                   KV   D  R+ +V ++I    
Sbjct: 396 ASDGVISCKVTKLDKNRVSRVLLEILPKP 424


>UniRef50_B8GZ20 Magnesium and cobalt efflux protein corC-like protein n=5
           Tax=Caulobacteraceae RepID=B8GZ20_CAUCN
          Length = 437

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 76/270 (28%), Positives = 135/270 (50%), Gaps = 4/270 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      L+  +         +E+ A++ +     LI+ + R M++ V+ + D+ VR  M
Sbjct: 160 STAAVLRLMGVRDERNTSVTSEEVEAVLAEGADAGLIEPEERSMIQEVLRLGDRPVRVAM 219

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPV-ISEDKDHIEGILMAKDLLPFMRSDAEA 132
            PR  +  +      +  L  I  SAHSR  V    D D   G+L+ KDLL    S  E 
Sbjct: 220 TPRRDLFWVSLADDTETVLKEIRASAHSRIVVATEGDLDGDVGVLLKKDLLDACLSG-EP 278

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +   ++Q + +PE+  + + L+ F+S   HMA+V+DEFG + G +T  D+LE+I G+ 
Sbjct: 279 LDLKAHVQQPLAIPETMSLLKALQLFKSTSLHMALVVDEFGSLQGAITPLDLLEMIAGDF 338

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVDTIGGLVMQAFGHLP 251
            +++D+++     +     W + A   I++ N+  G +F  D    T+ GL++   G LP
Sbjct: 339 PEDHDDDEKR-IIRREDGGWLIDARLDIQELNDHLGENFEADGGYHTVAGLILDRLGRLP 397

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKI 281
             GE ++I G+  ++   D  RI +V +K 
Sbjct: 398 TEGEHVEIGGFDLEIVDMDGSRIDKVILKP 427


>UniRef50_C0QRS4 CBS/transporter-associated domain protein n=5 Tax=Aquificales
           RepID=C0QRS4_PERMH
          Length = 429

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 82/280 (29%), Positives = 152/280 (54%), Gaps = 4/280 (1%)

Query: 14  NKKGFFSLLLSQLF-HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           + + F   +  +L       + D+L++++    +  +  E+ ++++E  + + +  V +I
Sbjct: 149 SAEYFLKKMGLELPVESHKLSEDDLISIVNIGTEKKIFTEEEKEIIEATLQLHETAVSEI 208

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR  +  + +  T+ E L++I E  +SR PV   + D+I GIL  KD++ F++ + + 
Sbjct: 209 MTPRRDIFAIPKGLTVREVLELIKEKDYSRIPVYEGNLDNIIGILYIKDII-FLKFEGKE 267

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +D+ LR+   VPE   +  ++K+F  ++ HMAIV+DE G V GLVT +DILE IVG+I
Sbjct: 268 EKIDRFLREPYFVPEFTPLLNLMKKFEEKKNHMAIVVDEHGTVVGLVTFQDILEFIVGDI 327

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLP 251
             E  E ++   +Q+S + W V     +E   E  G    D+ E DT+GG ++      P
Sbjct: 328 P-EEYEPEEPFIKQISMNKWEVSGKIEVEILEEVVGIKLPDDYEFDTVGGFILDVLKRFP 386

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
             GE    + Y+F++   +S RII V ++   ++ + + +
Sbjct: 387 EEGEEFVYENYKFRILKMESNRIISVLIEKLPETVKEEEE 426


>UniRef50_A6T3M6 Hemolysin n=3 Tax=Oxalobacteraceae RepID=A6T3M6_JANMA
          Length = 443

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 70/282 (24%), Positives = 127/282 (45%), Gaps = 12/282 (4%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
            +    +L       +    +E+  L R+     L ++   D++   + + DQRV  +M 
Sbjct: 157 TEFILRVLGMHHKKDDAVTEEEIAGLFREGTDAGLFEKTEHDIVSRALRLDDQRVAGLMT 216

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--EA 132
           PR  +  +     ++  L  I +S+++RFPV   D  H+ GI+ A  L            
Sbjct: 217 PRLDVHFIDLEDPIEVNLAKIADSSYNRFPVCKGDISHVIGIVHAGSLFEQAIRGKAINT 276

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             +    R  + VPE+    ++L+  +  R  +A+VIDE+G + G+VT+ D+L  +VG++
Sbjct: 277 VDIAAATRPPLFVPETISAMQLLETLKKNRAELALVIDEYGEIEGIVTLSDVLGALVGDV 336

Query: 193 E--DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAF--GTHFSDE---EVDTIGGLVMQ 245
              DE+ E D     +    +W +    S + F E       F +E      T+ G VM 
Sbjct: 337 SVIDEHHEVDG---VRRDDGSWLIDGGVSFDRFRELLETDVRFPEEASGTYHTLAGFVMT 393

Query: 246 AFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             GH+P   ++ + +GY+ +V   D  RI ++ +   D  P 
Sbjct: 394 FLGHIPQMSDSFEWEGYRIEVVDMDRNRIDRLLITKLDPGPD 435


>UniRef50_C9MVS3 CBS domain protein n=3 Tax=Fusobacteriaceae RepID=C9MVS3_9FUSO
          Length = 450

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 79/282 (28%), Positives = 163/282 (57%), Gaps = 6/282 (2%)

Query: 14  NKKGFFSLLLSQLFH-GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +     ++L  +  +  E  +++EL +L+    ++ +I+E  ++M+E +++  ++  R+I
Sbjct: 161 STNLVLTILKMKEDNIEEKVSKEELRSLVEVGKEHGVINETEQEMIENIIEFDEKIAREI 220

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL-LPFMRSDAE 131
           MIPR+++  + +N ++ E  +      +SR PV   + D+I G+L+ KDL +   +   +
Sbjct: 221 MIPRTKVFLIDKNISIHELFENKEIGKYSRIPVYENEADNIVGVLLTKDLMMEAYKKGFD 280

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              +  +L++A  VPE+K V+ +  E + ++ H+ I+IDE+GG SG+VT+ED++E ++G 
Sbjct: 281 NIKVADLLQEAYFVPETKNVNELFNEMQLEKKHITILIDEYGGFSGIVTLEDLIEEVMGN 340

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DE+D ++D+  RQLSR+ + +    S+ D N+ F      +  DT+ G++++  G++P
Sbjct: 341 IADEFD-DEDLSIRQLSRNKYLISGEVSLNDLNDNFNFELESKYYDTLSGILIENLGYIP 399

Query: 252 ARGETID---IDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
              E I+   I+G  FK     +++I +V +    D  + + 
Sbjct: 400 EDNENIEPITINGVVFKPQRVRNKKIEKVVMTFDKDKTEDEK 441


>UniRef50_A7VIV6 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A7VIV6_9CLOT
          Length = 268

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 77/269 (28%), Positives = 147/269 (54%), Gaps = 5/269 (1%)

Query: 21  LLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI 80
            L +     E K  +E+++++ +  +  LI +D  +M+  + + +++ VRD+M PRS ++
Sbjct: 2   KLFNNRKADEEKVEEEIISMVNEGNEQGLIHDDEVEMITNIFEFSEKEVRDVMTPRSDVV 61

Query: 81  TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLR 140
            + ++ T+DE + +++E+ +SR+PV  +D D+I GIL  KD +     D    ++++++ 
Sbjct: 62  GIDKHTTMDETIKIMLENNYSRYPVFDDDLDNIVGILYFKDFVKAYLQDKNQ-TIEQIMV 120

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
           +   V  +K +  + K  + ++ HM IV+DE+G   G++ +EDILE IVG I    + +D
Sbjct: 121 EPTFVHPTKNISELFKRMQKEKIHMVIVVDEYGQTEGIIAMEDILEEIVGNIF--DEYDD 178

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET--ID 258
           D D   L+ H + V   A +++ +E  G  F DE+  T+ G ++   G LP   E   I 
Sbjct: 179 DEDDIALAGHGYIVGGRAELDELSEHLGIEFPDEDFQTLNGFMLYELGRLPYENEKIDIT 238

Query: 259 IDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             GY F+      + I +V +   ++  Q
Sbjct: 239 YKGYNFETIGIKDKMIDKVRITKVENENQ 267


>UniRef50_C0QYZ5 Hemolysin protein n=2 Tax=Brachyspira RepID=C0QYZ5_BRAHW
          Length = 444

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 79/277 (28%), Positives = 133/277 (48%), Gaps = 6/277 (2%)

Query: 20  SLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQM 79
             L          + +++  +I    +  +I E T +ML GV+D  ++ V +IM PR  M
Sbjct: 149 KRLRDAEKRSALSSMEDITTIIHLGHKEGIIKEYTHEMLTGVIDFRNKTVEEIMTPRVDM 208

Query: 80  ITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS----- 134
           + ++    ++E + + +ES  SRFPV  E  DHI GI   + L           +     
Sbjct: 209 VCIEAETDVNEIIKLTVESGLSRFPVYEETVDHIIGIFHTRALFKEYVKGGGKMNKVKKK 268

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
               +     VPE+K +  +  + + ++  M I IDE+GG +GLVT+EDI+E I+G+IED
Sbjct: 269 AIDYIMLPYFVPETKTISSLFSDMQKKKLQMVITIDEYGGTAGLVTMEDIIEEIMGDIED 328

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARG 254
           E D+++    R   +    +   ASIED N+        EE  TI G V+    H+P   
Sbjct: 329 ESDKKEADVIRFKGK-RIIINGNASIEDVNKTLKLELEHEEYQTIAGYVIDMLDHIPETN 387

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           E   + GY+ ++   + RRI+++       +   + D
Sbjct: 388 ERFILKGYRVRIMKVEDRRIVEMEFTPIKFARTNESD 424


>UniRef50_C1DQL5 Hemolysin-like protein n=2 Tax=Proteobacteria RepID=C1DQL5_AZOVD
          Length = 432

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 72/279 (25%), Positives = 119/279 (42%), Gaps = 7/279 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      L+        P   +E+  L+    +  +  E  +  +  V+ + +Q V  IM
Sbjct: 156 SCNLLLRLIGIGRRDEPPITDEEIQVLMEQGAEAGVFHESEQAFVANVLHLDEQPVGAIM 215

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
            PR Q+  +  +   +E L  + ES ++R  V       + G+L   DLL       +  
Sbjct: 216 SPRQQVYAIDLDDPREEQLRRLAESPYTRVLVCRGGLHRLVGVLHRGDLLKPALQG-QPI 274

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            + +  R    V ES     +L++FR  R   A+V+DEF  + G+VT+ D+L  IVGEI 
Sbjct: 275 DLQRSARPPFYVEESASSTGLLEDFRRTRNEFAVVVDEFDDLQGIVTLRDVLTAIVGEIP 334

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH--FS---DEEVDTIGGLVMQAFG 248
           D    + +    +    +W V     IE    A      F    D    T+ GLVM    
Sbjct: 335 DAL-HDGEPAIVRREDGSWLVDGGMGIEQLKTALDIDAAFPGEADNAYRTLAGLVMHCLQ 393

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            +P+  +  ++DG++F+V   D  RI +V V  P   P 
Sbjct: 394 RVPSVSDHFELDGWRFEVVDMDRTRIDKVLVMRPSAPPA 432


>UniRef50_D0LKP6 Putative uncharacterized protein n=1 Tax=Haliangium ochraceum DSM
           14365 RepID=D0LKP6_HALO1
          Length = 420

 Score =  285 bits (730), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 79/275 (28%), Positives = 133/275 (48%), Gaps = 5/275 (1%)

Query: 12  ISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDL--IDEDTRDMLEGVMDIADQRV 69
           +S+     + +L          RDEL  +I    +     I ++ R M+  V++++    
Sbjct: 144 LSSFASTMTRVLGTPAERALITRDELAMIIEAEPREGASEITQEERQMIANVLELSQAGA 203

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
            D+M+P S++  L  +  L +    + +  HSR PV     D++ G++   DLL      
Sbjct: 204 VDVMVPLSEVTALPESTPLADAALEVADKQHSRMPVYEGRVDNVIGVVHVFDLLQASTES 263

Query: 130 AE-AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
           A    ++ +V R A  VPE+     +L E +    HMAIV+DE+GG  G+VT+ED+LE +
Sbjct: 264 AAGTRTVAEVARPATFVPETMPAGDLLVELQKTGRHMAIVVDEYGGAVGIVTVEDLLEEV 323

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAF 247
           VGEI+DE+D       R      W V A   +E  NE       + E+ +T+ GL++  F
Sbjct: 324 VGEIDDEHDRP-PALIRPERPGVWWVAARTPVERLNEELSLSLPESEDYETVAGLLLDHF 382

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIP 282
             +P +GE++ I+    +V  A  R +  V +   
Sbjct: 383 KRIPEQGESMVIEQVTIRVLEASERAVEAVQILRR 417


>UniRef50_D2BD19 Putative uncharacterized protein n=1 Tax=Streptosporangium roseum
           DSM 43021 RepID=D2BD19_STRRD
          Length = 533

 Score =  285 bits (730), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 84/280 (30%), Positives = 146/280 (52%), Gaps = 9/280 (3%)

Query: 14  NKKGFFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +  G   LL        E  + +EL  ++    Q   +D   R ++  V     +++R++
Sbjct: 160 STDGVVKLLGGNPEADREEISTEELRDMV-VGHQELTLD--ERHLIAEVFAAGKRQLREV 216

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M+PR+++  +  +  L E   +     HSRFP+  +  D I G +  +DLL  + +    
Sbjct: 217 MLPRTEVEFMSADTRLAEAAVLAAAMPHSRFPIYRDSYDDIVGFVHIRDLLDPVLTG-SI 275

Query: 133 FSMDKV--LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
             + ++  +R   +VP SKRV   L E R + +H+AIV+DE+GG +G+VT+ED++E ++G
Sbjct: 276 EPISELVPIRPVKLVPTSKRVLATLSEMRGEGHHLAIVVDEYGGTAGIVTLEDLVEELIG 335

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHL 250
           +I DE+D ED+     L      +  LA++++     G   +D   +T+GG VM A GHL
Sbjct: 336 DIRDEHDVEDEQVV--LPAGEVELDGLANLDEVATETGIRLADGPYETLGGFVMAALGHL 393

Query: 251 PARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKL 290
           P  GE ++I G++  V   D RR+ +V +K     P+   
Sbjct: 394 PTLGERVEIPGFEMSVTDMDGRRVSRVRIKRRTVPPETPD 433


>UniRef50_C1DDZ1 Mg/Co transporter-like protein n=7 Tax=Pseudomonadaceae
           RepID=C1DDZ1_AZOVD
          Length = 426

 Score =  285 bits (730), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 73/280 (26%), Positives = 139/280 (49%), Gaps = 6/280 (2%)

Query: 15  KKGFFSLLLS--QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
             G   L     Q         +EL +++ +SG+   +  + R ML G++D+    V DI
Sbjct: 150 SNGLLRLAGIAPQGKGSASLTSEELRSMLHESGE--TLSPNRRGMLLGILDLERVSVNDI 207

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA-E 131
           MIPR++++ L  ++T++  ++++  ++H+R PV   D + IEG++  + +   +  +   
Sbjct: 208 MIPRNEVVGLDLDETMEAMVELLRSTSHTRLPVFRGDINRIEGVVHMRHIAHLLTRNRLT 267

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
             ++ +  ++   VPE+  +   L +F+ Q+  +AIV+DE+G V G+VT+EDIL  IVGE
Sbjct: 268 KENLREACQEPYFVPENTPLAVQLIQFQQQKRRIAIVVDEYGDVQGIVTLEDILGEIVGE 327

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
                D +   D R     +  +   A + + N+  G     +   T+ GL+ +A  ++P
Sbjct: 328 FT-NRDHQFAPDIRAQEDGSQIIDGAAHVREVNKTLGWQLPSDGPRTLNGLITEALQNIP 386

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
             G  + I  Y+ ++      R+  V V   D  P P  +
Sbjct: 387 DCGVCLSIGPYRLEILETSGNRVKNVRVWTADARPSPTHE 426


>UniRef50_D2NT77 Hemolysin n=2 Tax=Rothia mucilaginosa RepID=D2NT77_9MICC
          Length = 488

 Score =  285 bits (730), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 88/280 (31%), Positives = 148/280 (52%), Gaps = 14/280 (5%)

Query: 7   HSSDTISNKKGFFSLLLSQLFHGEPK-------NRDELLALIRDSGQNDLIDEDTRDMLE 59
           + S  +S   G    L  +L             + +EL   +  +   + I++D   M++
Sbjct: 136 YLSVLLSPATGLLDKLSVRLAPERSAEAPVGVFDEEELREFLDRASDAETIEDDEAQMVQ 195

Query: 60  GVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMA 119
            V ++ D R+R +M+PR+ M+T  R+  L E L + + S +SR PVI +  D I G+L  
Sbjct: 196 SVFEMDDTRIRSLMVPRTDMLTASRDTPLREALSLFLRSGYSRMPVIGDSSDEILGVLYL 255

Query: 120 KDLLPFM------RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFG 173
           KD +                ++ +++R A   PESKR   +L+E + +  H+AI++DE+G
Sbjct: 256 KDAMRAFILHGEAPEGTALPTVVELMRPARFEPESKRAMDLLREMQRESTHVAIIVDEYG 315

Query: 174 GVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD 233
           G +GL+T+ED++E +VG+I DEYD E   ++      T+ + A   I++  E FG    D
Sbjct: 316 GTAGLITLEDLIEELVGDISDEYDHER-PEYTLNDDGTFRLSARLGIDELGEIFGRELDD 374

Query: 234 EEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRR 273
           E+VDT+GGL+ +  G +P  G  I+IDG   +   +  RR
Sbjct: 375 EDVDTVGGLLAKHLGMVPIVGSEIEIDGIHIRAIGSSGRR 414


>UniRef50_B1YJR8 Putative uncharacterized protein n=1 Tax=Exiguobacterium sibiricum
           255-15 RepID=B1YJR8_EXIS2
          Length = 427

 Score =  285 bits (730), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 79/272 (29%), Positives = 132/272 (48%), Gaps = 2/272 (0%)

Query: 21  LLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI 80
           LL+     G      EL AL+  S +  ++DE   +++   +D  +  V + + PR+ + 
Sbjct: 155 LLIGADPKGPLVTEQELRALVDISEEEGVMDEAGAEIVHRAVDFKNVTVEEALTPRTNIQ 214

Query: 81  TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLR 140
            +  +   DE L  + +   SR PV  +  DHI G+L  +D L           + +++R
Sbjct: 215 AIDIDAGFDEILREVQKDGFSRLPVYKDSIDHIIGVLSERDFLREFVKHGR-VEIRELIR 273

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
               V     +  +L E + ++ HMA+V+DEFGG +GL+T+EDILE +VGEI DE+DE  
Sbjct: 274 PVSFVVPQTHIIDLLPELKVKQSHMAVVLDEFGGTAGLITLEDILEELVGEIWDEHDESL 333

Query: 201 DIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDID 260
           +   +Q+S + +   A   IEDF   F     + E  ++GG +M+  GH+P  G  +   
Sbjct: 334 EYT-KQVSPNRYECLAEYDIEDFCHQFDLAMPETEAQSLGGWIMEDVGHIPEVGTQMVYG 392

Query: 261 GYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
                V   ++RR+  V        P    D+
Sbjct: 393 PLTLTVLHVENRRVRTVSAVFSQHEPSEGTDD 424


>UniRef50_Q01P08 CBS domain containing protein n=1 Tax=Candidatus Solibacter
           usitatus Ellin6076 RepID=Q01P08_SOLUE
          Length = 420

 Score =  284 bits (729), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 78/263 (29%), Positives = 142/263 (53%), Gaps = 4/263 (1%)

Query: 27  FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQ 86
            + EP   + + ALI    +  LI+E+ R +++ V++  D+ VR++M PR  ++ +  + 
Sbjct: 160 ANEEPTPAENIEALISAGTEEGLIEEEDRKLIQSVVEFGDKVVREVMTPRPNIVAIAADA 219

Query: 87  TLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVP 146
           TL++   ++I   +SR PV     D++ G +  +D+      + E  ++  ++R  ++VP
Sbjct: 220 TLEQLRQLVITEQYSRIPVYEGTIDNVIGFVHVRDMFELQEEEREKRTVRGLVRNIMLVP 279

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           E+K V  +++  + +  HM IV+DE+G  +GL T+ED+LE+I+GEI DE+  E D D  +
Sbjct: 280 ETKPVSVLMRRMQQENTHMVIVVDEYGNTAGLATMEDLLEVIIGEIRDEH--EPDSDVAE 337

Query: 207 LSRHTWTVRALASIEDFNEAFGT--HFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQF 264
             R  + V     ++   +   T     D E  T+GGLV +  G +P  GE ++ DG + 
Sbjct: 338 DGRGGFIVSGSFDLDRITDLIDTFHRGDDIESTTVGGLVSEWLGRVPKTGEFVERDGVRL 397

Query: 265 KVAMADSRRIIQVHVKIPDDSPQ 287
           +V  +D  R+ QV +       Q
Sbjct: 398 EVLASDELRVGQVRISKSQTVAQ 420


>UniRef50_C4G6D4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G6D4_ABIDE
          Length = 395

 Score =  284 bits (729), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 86/274 (31%), Positives = 142/274 (51%), Gaps = 2/274 (0%)

Query: 15  KKGFFSLLLSQLFHGEP-KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
             G   +              +ELL  +  S +  +I+ + ++M+  V+D  D   +D+M
Sbjct: 110 SNGILKIFGIDPEENTSGITENELLTYVEVSHEEGIIENEEKEMITNVVDFGDSLAKDVM 169

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
           +PR  M T+  + + DE L    E  +SR PV  E+ D+I GI+  KD+  F + D + F
Sbjct: 170 VPRVDMYTISDDISYDELLLAFEEDKYSRLPVYRENVDNIIGIVYLKDV-AFYKGDKKDF 228

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            +  +LR A    E K+   +L E R     M IV+DE+G   GL+T+ED+LE IVG+I 
Sbjct: 229 KLGSILRPANFTYEFKKTSELLIEMRKSSLSMCIVLDEYGSAVGLITLEDLLEEIVGDIR 288

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPAR 253
           DEYD ++  D  +L +  + V     ++DFN+ FGT +  ++ D+I G +++ F  LP +
Sbjct: 289 DEYDVDEVDDIVRLDQDEFMVLGSTRLDDFNDFFGTEYISDDYDSIAGKLIELFERLPEK 348

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           G+ I      F +   D RRI ++ V+    +  
Sbjct: 349 GDAITDGSLSFLIESIDHRRIEKIKVRKLPSTSD 382


>UniRef50_C8NR98 Transport protein n=2 Tax=Corynebacterium efficiens
           RepID=C8NR98_COREF
          Length = 445

 Score =  284 bits (727), Expect = 3e-75,   Method: Composition-based stats.
 Identities = 71/291 (24%), Positives = 134/291 (46%), Gaps = 19/291 (6%)

Query: 14  NKKGFFSLLLSQL-FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
           +      LL        E    +E++ ++         ++  R+++  V +  D+ V +I
Sbjct: 159 SSNLLLRLLGFDPDARTEDMTEEEVVEIVTSFE---GFEQGEREIVADVFEANDRLVTEI 215

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M  RS ++  + ++++ E +D I    +SR+PV  E  D   G +  + LL         
Sbjct: 216 MRHRSDVVAFEASESVAEVVDAIRNQPYSRYPVYEETIDDTIGFIHVRGLLEAATRGEGD 275

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
             + ++ R     P + R+   +++ R+   H+A+V+DE+GG  GLVT+ED+LE +VGEI
Sbjct: 276 LPLREIARPIQYFPGTLRLPAAMRQMRASGNHIAMVVDEYGGTDGLVTLEDLLEELVGEI 335

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPA 252
            DEYD ++     QL   +  + A  ++EDF +  G    +   +T+ G ++   G L  
Sbjct: 336 WDEYDRDEHRAVMQLHE-SQLMDASTNLEDFADVSGILLPEGPYETVAGWIVMKLGRLGR 394

Query: 253 RGETIDID--------------GYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            G+ ++I                Y+ ++A     RI +V +   D  P  +
Sbjct: 395 VGDVVEIPADYTIDAEDDAGDIRYELEIAEVRGNRITRVKLSKTDGPPTQE 445


>UniRef50_A5CRB2 Conserved membrane protein n=4 Tax=Actinobacteria (class)
           RepID=A5CRB2_CLAM3
          Length = 440

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 82/252 (32%), Positives = 149/252 (59%), Gaps = 6/252 (2%)

Query: 33  NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECL 92
           + ++LL+++ ++ + ++++ED R+++  + +  D  VR++MIPR+ M+ +++   +   L
Sbjct: 162 SEEQLLSMVDEATELEVLEEDDRELIHSIFEFNDTVVREVMIPRTDMVVVEQTAHVGSAL 221

Query: 93  DVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA---FSMDKVLRQAVVVPESK 149
            + +    SR PV   D D IEG+L  +DL   +    E     ++D++ R AV VPES+
Sbjct: 222 GLFLSRGISRAPVTGRDSDEIEGVLYLRDLARMVYERPEEAERTTVDQLARPAVFVPESQ 281

Query: 150 RVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSR 209
           + D +L++ + +  H+A+V+DE+GG++GLVT+ED++E +VG+I DEYD  D  +F  L  
Sbjct: 282 KADALLRQMQLESNHLAMVVDEYGGIAGLVTLEDLIEELVGDISDEYDR-DVPEFEDLGD 340

Query: 210 HTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMA 269
             + V A   I++  + FG    D++VD+ GGL+ +  G LP RG  + + G        
Sbjct: 341 GVYRVSARLPIDELGDLFGLELDDDDVDSAGGLLAKTLGRLPERGSVVRVGGLVLTADRV 400

Query: 270 DSR--RIIQVHV 279
           + R  RI  + V
Sbjct: 401 EGRRTRISTILV 412


>UniRef50_C9LYN4 CBS domain protein n=2 Tax=Selenomonas RepID=C9LYN4_9FIRM
          Length = 481

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 80/260 (30%), Positives = 143/260 (55%), Gaps = 2/260 (0%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
              +E+  L+ +S +   ID+   + ++ V D AD  VR+IMIPR+ M+ L    +L+E 
Sbjct: 195 HTEEEIRVLMEESHRQGFIDKTELEFVDNVFDFADLSVREIMIPRTDMVCLDLEDSLEES 254

Query: 92  LDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRV 151
           +++ +E   +R+P+    KD+I G L  KD L  +    E   + K+ R A+VVPE+  V
Sbjct: 255 IEMAMEERLTRYPICDGGKDNIIGFLHIKDFLQTLYKKEEP-DLRKLARHALVVPEAMAV 313

Query: 152 DRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHT 211
            R+L+  + +R  +AIV+DE+GG +G+VTIED++E IVG+I+DE+D +  +   +     
Sbjct: 314 SRLLQTMQQERSQLAIVVDEYGGTAGMVTIEDVIEEIVGDIQDEFDTDRPL-VEKKGACL 372

Query: 212 WTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADS 271
           ++V A   +E+  +       +EE+D++GG +     + P  G+       QF V   + 
Sbjct: 373 YSVDAKMLLEELEDILEVAIDEEEIDSVGGWLSAHVDNPPRIGQKAAFGDAQFFVEETEG 432

Query: 272 RRIIQVHVKIPDDSPQPKLD 291
            RI +V  ++  +  +   +
Sbjct: 433 VRITRVLCRLGRELQKEHDE 452


>UniRef50_C0W0A3 HCC HlyC/CorC family transporter n=1 Tax=Actinomyces coleocanis DSM
           15436 RepID=C0W0A3_9ACTO
          Length = 429

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 86/260 (33%), Positives = 145/260 (55%), Gaps = 5/260 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           +E+  ++ + G+    +E+ R+ML  V ++    VR++M+PR++M+T+    T+DE LD+
Sbjct: 171 EEMREVVDEVGETSGFEEEDREMLRSVFELGYTLVREVMVPRTEMVTIAAETTIDEALDL 230

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS--DAEAFSMDKVLRQAVVVPESKRVD 152
            + S +SR PVI +D D I GI+  KD++  +R   D +   +  V R+   VPE    D
Sbjct: 231 FVTSGYSRIPVIEDDIDDIVGIVYFKDVISRLRRRPDDKQVPVRNVCREPRFVPEVVLAD 290

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
             L++ ++ R H+A+V+DE+GG++GLVTIED+LE IVGE+ DE+D        ++S   W
Sbjct: 291 DELRQMQASRVHLALVVDEYGGIAGLVTIEDLLEEIVGELTDEHDRNVTQP-EEISEGVW 349

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V A  S+ +  E  G    DE+VD++GG + +  G +P  G++ + D        A  R
Sbjct: 350 RVPARFSLWELGELLGVELEDEDVDSVGGYLAKLLGKVPLPGDSAETDDIMITAEEAVGR 409

Query: 273 R--IIQVHVKIPDDSPQPKL 290
           R  +  V      ++     
Sbjct: 410 RRQVGTVVATRKTEAESEAE 429


>UniRef50_A9BXY0 CBS domain containing protein n=17 Tax=cellular organisms
           RepID=A9BXY0_DELAS
          Length = 307

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 114/292 (39%), Positives = 167/292 (57%), Gaps = 8/292 (2%)

Query: 1   MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEG 60
           +SD +   S    +K+ F    +++  H  P + DEL+  + D+  N +I  ++R MLE 
Sbjct: 15  VSDPHPARSSEKESKRSFLQK-VAEFIHPAPDSPDELIETLADAEDNQVIGPESRVMLER 73

Query: 61  VMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK 120
           V+ +AD    D+M+   +M  +  +   DE L  +I +AHSRFPV   ++++I GIL+AK
Sbjct: 74  VIRMADMTAGDVMVAAPRMDLVNIDAPFDELLHQVITTAHSRFPVYQGERENIIGILLAK 133

Query: 121 DLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVT 180
           DLL   RS     ++  +LR A  VPESK ++ +L+EFR  R H+A+VIDEFG V+GLVT
Sbjct: 134 DLLKLQRS--PDLNIRALLRPAAFVPESKGLNDLLREFRGNRNHLAVVIDEFGRVAGLVT 191

Query: 181 IEDILELIVGEIEDEYD-EEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHF----SDEE 235
           IED+LE IVGEIEDE+D  ED+ D   L+ +++ V    +IE  NE F         D+E
Sbjct: 192 IEDVLEEIVGEIEDEFDIPEDEGDIFALADNSYRVAGDTTIEHVNETFEVALHARDPDDE 251

Query: 236 VDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
            DTIGGL+    GH+P RGE I + G +F V       +    V     +  
Sbjct: 252 FDTIGGLIAHEMGHVPKRGEQIHLAGLEFTVLHTKGGAVRWFKVVRDPAADS 303


>UniRef50_B6FYX0 Putative uncharacterized protein n=1 Tax=Clostridium hiranonis DSM
           13275 RepID=B6FYX0_9CLOT
          Length = 446

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 81/262 (30%), Positives = 142/262 (54%), Gaps = 17/262 (6%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           +  ++        I+ D ++ ++ V D +D  VR+IM  +S+++ +  + +L E  + I 
Sbjct: 186 IRMMLEIGNTGGTINSDEKEWIDNVFDFSDSSVREIMTHKSEVVGIYTDDSLMEIEEKIH 245

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRS-------------DAEAFSMDKVLRQAV 143
           E+ +SR+PV  E+ + I+GIL AKD    + +             +    ++   LR+  
Sbjct: 246 ETGYSRYPVYGENDNDIKGILYAKDFFAEVYNCFAKEDDDLGVVVNKNELNIMDNLRKPY 305

Query: 144 VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDID 203
            +P+S     + K  +    H+AIVI+E+G   GL+T+ED+LE IVG I DEYDE DD D
Sbjct: 306 FIPDSMSSLLLFKNMQKNNTHIAIVINEYGENIGLITMEDLLEEIVGNIYDEYDECDDGD 365

Query: 204 FRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARGETIDID-- 260
             ++S  TW ++   S++D ++ F   F D+ + DTI GL++     +P  GE  +I+  
Sbjct: 366 V-KISETTWKIKGSTSLDDLSDKFDIDFPDDLDYDTISGLILAKIQRIPNDGEKFEIEAF 424

Query: 261 GYQFKVAMADSRRIIQVHVKIP 282
           G + KV   ++R+I +V + I 
Sbjct: 425 GMKIKVEKVEARKIEEVIITIV 446


>UniRef50_Q8PS13 Conserved protein n=2 Tax=Methanosarcina RepID=Q8PS13_METMA
          Length = 436

 Score =  283 bits (726), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 75/275 (27%), Positives = 132/275 (48%), Gaps = 6/275 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      LL  +   G P   +E+  +I +  +  + +     M+EGV DI D+RV  +M
Sbjct: 160 STDAVLRLLRVRKIIGPPVTEEEIKIMIEEGTEAGVFERAEMSMIEGVFDIGDRRVESLM 219

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAF 133
             RS +I L  +  +DE L  +I S  S FPV   D D + GI+  KD+L  +    +  
Sbjct: 220 THRSDIIALDLDDPVDENLKKMIASGRSNFPVYERDLDDVIGIVSVKDVLAKLVESGK-V 278

Query: 134 SMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIE 193
            +   + + +  PE+  + ++L+ F+    H+A++ DE+G V G++T+ DILE IVG++ 
Sbjct: 279 DIRASVTKPLFAPEAITILKLLESFKETGMHIALITDEYGSVQGIITLHDILEAIVGDVR 338

Query: 194 DEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTH-FSDEE---VDTIGGLVMQAFGH 249
              + E++     L   +W +     +           F  EE     TI GL+M     
Sbjct: 339 SLGEPEEE-QITVLENGSWLIDGDTPVNKLKYVLSVDSFPGEEQGYYLTIAGLIMYILQR 397

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
           +P  G+ ++ +G +++V   D  RI +V V    +
Sbjct: 398 IPKTGDHMEFNGLRYEVVDMDGIRIDKVMVTKVPE 432


>UniRef50_UPI0001B44AE5 CBS domain protein n=1 Tax=Listeria monocytogenes FSL N1-017
           RepID=UPI0001B44AE5
          Length = 396

 Score =  283 bits (726), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 81/275 (29%), Positives = 139/275 (50%), Gaps = 6/275 (2%)

Query: 12  ISNKKGFFSLLLS--QLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           +S        L    +    E   R+E+  LI    ++ +I+ +   ML GV ++ ++  
Sbjct: 112 LSFSTDILVKLTRMEKNTDNEKMTREEMQLLIETGRRDGVIEVEELQMLRGVFEMDNKYA 171

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS- 128
           R++M+PR+    +      +E  D ++    SR PV + D+D + GIL  KD     R  
Sbjct: 172 REVMVPRTDAFMVDAEIESEELCDALLSENFSRVPVYTGDQDSVLGILHMKDFFAEARKS 231

Query: 129 DAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELI 188
             E   +  +++ A    E+  +D +LK  +  R  MAI++DE+GGV+G+VT+ED+LE I
Sbjct: 232 GFENIDVKALVKDAYFAQETMFIDDLLKNMQRTRNQMAILMDEYGGVAGIVTVEDLLEEI 291

Query: 189 VGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFG 248
           VGEI+DE D   D + +++   T+ V    S++DFNE F        VDT+ G V+   G
Sbjct: 292 VGEIDDENDVFSD-EVKKIDETTFIVEGRMSLDDFNEMFHVELPSRGVDTVAGFVLTLTG 350

Query: 249 HLPARGET--IDIDGYQFKVAMADSRRIIQVHVKI 281
            +P   +   ++    +F V   +  R++ V V+ 
Sbjct: 351 TIPEEDDKVVVEYGTLRFTVEEMNDARLVSVRVEK 385


>UniRef50_Q2W097 Putative Mg2+ and Co2+ transporter CorB n=1 Tax=Magnetospirillum
           magneticum AMB-1 RepID=Q2W097_MAGSA
          Length = 430

 Score =  283 bits (725), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 80/276 (28%), Positives = 134/276 (48%), Gaps = 7/276 (2%)

Query: 17  GFFSLLLSQLFHGEPK--NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           G F L  ++         +  EL   I      +    + R ML  ++++ D  V  +M 
Sbjct: 155 GLFRLFGAKYSTAVSVEASMMELKGAIEV-HAGEEEVREERRMLRSILELGDVEVEQVMT 213

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPF---MRSDAE 131
            R  ++T        E L++++ S  SR P+  +D D+I G++ AKDLL     +  + +
Sbjct: 214 HRRGVVTADAGLPAAEILELVVSSPFSRVPLWKDDPDNIVGVVHAKDLLRAVRALDGELD 273

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
              + ++      +P+S  +   L+ FRS+R H A+V+DE+G + G+VT+EDILE IVG+
Sbjct: 274 KLDVVELASPPWFIPDSTTLLEQLQAFRSRREHFALVVDEYGTLMGVVTLEDILEEIVGD 333

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DE+D       R  S  ++ V    +I D N  F     DEE  TI GL++     +P
Sbjct: 334 IADEHDVA-VAGVRPQSDGSYIVDGSVTIRDLNREFEWRLPDEEAATIAGLILHEARQIP 392

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             G+     G++F++A     +I  + V  P  +P 
Sbjct: 393 DVGQVFRFYGFRFEIARRQRNQITSIRVMPPAPAPS 428


>UniRef50_C0GM71 CBS domain containing protein n=1 Tax=Desulfonatronospira
           thiodismutans ASO3-1 RepID=C0GM71_9DELT
          Length = 270

 Score =  283 bits (725), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 82/248 (33%), Positives = 150/248 (60%), Gaps = 2/248 (0%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           L  +IR++ +   I  +   ML  ++ + +++  +IM+PR+ ++  + N TL +  + I+
Sbjct: 25  LEEVIREASEEGEIKNEEVRMLLNILRLHEKQAVEIMVPRTDLVCAEENDTLKDVAESIL 84

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLK 156
           +S HSR PV  E+KDHI G++ AKDLL     + +  S++ ++R+   +PE+K V ++L 
Sbjct: 85  QSGHSRLPVYRENKDHIVGLIHAKDLLQHFFENKD-VSVNSLMREPHFMPETKNVRQILM 143

Query: 157 EFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRA 216
           +F++Q+ H+ +V+DE+GG SG+VT+ED+LE IVGEIEDEYD     + + +   T+ V  
Sbjct: 144 DFQNQKIHLGVVLDEYGGTSGIVTLEDVLEEIVGEIEDEYDPPRPQEVQTMDDGTYYVAG 203

Query: 217 LASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ 276
             S+++  +  G     E+V+TIGG +    G +P +GE    + + + V  A+++ I  
Sbjct: 204 RTSLDELAD-IGIKIPTEQVETIGGYISHLAGKVPVKGEEFSDEFFSYVVQEANTKNIQW 262

Query: 277 VHVKIPDD 284
           + ++  D 
Sbjct: 263 LTIRRLDP 270


>UniRef50_C7MLQ1 CBS domain-containing protein n=8 Tax=Coriobacteriaceae
           RepID=C7MLQ1_CRYCD
          Length = 443

 Score =  283 bits (725), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 82/261 (31%), Positives = 141/261 (54%), Gaps = 7/261 (2%)

Query: 11  TISNKKGFFSLLLSQLFHG-EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRV 69
           T ++      L   +     +  + DE+  +++D+ +   +  D + M+  ++D+AD   
Sbjct: 157 TAASSNALARLFHVKSVDERQAVSEDEIKYIVKDNEE---LLPDEKRMIHEILDLADATA 213

Query: 70  RDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD 129
           RDIM PR+ +I ++  +T+ E L+ +  + +SR PV  ED D I G++  KDL+P +  D
Sbjct: 214 RDIMTPRADIIFVEDTETVKETLNRMRGTGYSRLPVYHEDYDRIVGVVKYKDLIPAIMDD 273

Query: 130 AEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIV 189
            E  ++D+   +   VPE+K +  +L E ++ R  +AIV+DE+GG  GL+TIEDI+E IV
Sbjct: 274 REDATVDEFTDEVYFVPETKDIFPLLSEMQTNRQQIAIVVDEYGGTDGLITIEDIVEEIV 333

Query: 190 GEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFG 248
           GEI DE D  +     QL+   W V     ++D  E       + ++ +TI G ++    
Sbjct: 334 GEIIDETDL-ESRYVTQLTDGEWLVDGSLPVDDAIE-LSWPLEESDDYETIAGWLIDMVD 391

Query: 249 HLPARGETIDIDGYQFKVAMA 269
            +P  G++ D  GY+F V   
Sbjct: 392 TIPQIGDSYDFGGYRFTVQSM 412


>UniRef50_C6J7K3 Putative uncharacterized protein n=2 Tax=Bacillales
           RepID=C6J7K3_9BACL
          Length = 454

 Score =  283 bits (725), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 78/246 (31%), Positives = 144/246 (58%), Gaps = 3/246 (1%)

Query: 37  LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVII 96
           +  L+  S ++ +ID+D   +++ + D +D   R++M+PR+ M  L  N + ++ + ++ 
Sbjct: 200 IRILMDQSAKSGVIDKDEMKLVDNIFDFSDMLAREVMLPRTDMDCLYTNLSWEDNMKIVA 259

Query: 97  ESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLK 156
            + HSR+PV  EDKD I G +   DLL  +    +   +++++R  + VPES  + ++L+
Sbjct: 260 NTKHSRYPVAVEDKDQIIGFVHITDLL--LPDSEKPLRLEEMVRPILNVPESMEISQVLR 317

Query: 157 EFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRA 216
             + +   + +V+DE+GG +GL+T E+ILE IVG++ DE+ E++  D  +++   ++V  
Sbjct: 318 LMQKKHSQVTLVVDEYGGTAGLLTAEEILEEIVGDLHDEF-EDERPDIEKITDDVYSVDG 376

Query: 217 LASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ 276
              IE+ NE  G+   DEEVD+IGG + +     PA+G+   +D + F+V  A   RI +
Sbjct: 377 RLLIEEVNELVGSDIEDEEVDSIGGWLFKELEGTPAKGKRKQVDRFLFEVEEASRLRITR 436

Query: 277 VHVKIP 282
           V V   
Sbjct: 437 VKVIRL 442


>UniRef50_C1F1N4 CBS/transporter domain protein n=1 Tax=Acidobacterium capsulatum
           ATCC 51196 RepID=C1F1N4_ACIC5
          Length = 457

 Score =  282 bits (724), Expect = 8e-75,   Method: Composition-based stats.
 Identities = 79/294 (26%), Positives = 142/294 (48%), Gaps = 16/294 (5%)

Query: 13  SNKKGFFSLLLSQLFH-GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           S+         + + H G   + +EL+ +   + +  ++ E    ++   +++ +   R+
Sbjct: 161 SSAALVLRAFDTPIAHQGGVHSSEELMLMATAARRMGVLPEFEETLIHRSLELDELLTRE 220

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDH--IEGILMAKDLLPFMRSD 129
           IM PR QM  L  +  +++    I+   HSR PV    + H  I G++ AKD+   M   
Sbjct: 221 IMTPRQQMFALPFDLPIEQASARIVAEMHSRIPVYDPARGHEFIVGVVYAKDIARLMHFR 280

Query: 130 AEAFS-----------MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGL 178
           A A +           + +V+R+ +VVPE+K V  +L+EF+ +R H+AIV+DE+G   GL
Sbjct: 281 ASAQTRFSSEPFSGMLLRQVMREVLVVPETKPVLDLLREFQQRRRHLAIVVDEYGSTIGL 340

Query: 179 VTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-DEEVD 237
           VT+ED +E ++GE+EDE+D        + S     +    ++ D           +  V+
Sbjct: 341 VTVEDAIEQLIGEVEDEFDLAPPSLLARTS-GELVLDGSVTLRDLETQMHWDLPREGGVE 399

Query: 238 TIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
           T+ G V+   G +P +GE+I  DG +  V   +  RI ++ V+          D
Sbjct: 400 TLAGFVLTQLGKIPEQGESIVYDGRRLTVMEMEGNRISRIRVQELPSMKDDTGD 453


>UniRef50_C4GB29 Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles
           DSM 14600 RepID=C4GB29_9FIRM
          Length = 290

 Score =  282 bits (723), Expect = 9e-75,   Method: Composition-based stats.
 Identities = 76/282 (26%), Positives = 152/282 (53%), Gaps = 8/282 (2%)

Query: 13  SNKKGFFSLLLSQLFH-GEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           S+K  FFS L  +     E +  ++L++ IR+  +  ++      M+  +   AD+ V+D
Sbjct: 6   SSKNKFFSRLFHRDEALSEDEFEEDLISKIREGHEQGVLSAREVTMIRNIFAFADKDVKD 65

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM  RS ++ +    T+ E ++ +IE+ +SR+PV  ++ D+I G++  KD L ++    +
Sbjct: 66  IMQHRSNIVAIDGESTMQEAVEQMIENHYSRYPVYIKNLDNIIGLVHIKDTLRYVAEGHD 125

Query: 132 ----AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
                  ++ ++R+ + VP++  +D +L + + ++ HM +V DE+G   GL+++ED++E 
Sbjct: 126 MSVKLRDLEYMVRRVIFVPQTHSIDTLLAQMQHRKNHMILVQDEYGQTCGLLSMEDVIEE 185

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           IVG I+DEYD+ED++   +L    + ++    ++   +  G   SDEE +T+ G +++  
Sbjct: 186 IVGNIQDEYDDEDEL-VARLGDGAYMMQGSTPLDTVADTLGIDLSDEEAETLNGFLLEKL 244

Query: 248 GHLPARGETIDI--DGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           G +P   E+ D+   GY F V   +    + V +        
Sbjct: 245 GRIPQDHESFDVTARGYHFHVIDVEHMVALGVRISREASLED 286


>UniRef50_A9NG07 Membrane-anchored CBS-domain containing protein n=1
           Tax=Acholeplasma laidlawii PG-8A RepID=A9NG07_ACHLI
          Length = 449

 Score =  282 bits (723), Expect = 9e-75,   Method: Composition-based stats.
 Identities = 71/285 (24%), Positives = 136/285 (47%), Gaps = 7/285 (2%)

Query: 11  TISNKKGFFSLLLSQLFHGEPKNRDELLALI--RDSGQNDLIDEDTRDMLEGVMDIADQR 68
            +++       L       +     E   ++    S     ID    +M++ + +     
Sbjct: 158 LLTSSANLIIRLFGINPQDDDDTLSEEELILELNASESKGFIDSSENEMIQNIFEFDSTT 217

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFM-- 126
           V ++M  R+++  +  N T DE +  +    ++RFPV  E  D I G L  KDLL ++  
Sbjct: 218 VEEVMTHRTEVSAINVNSTRDELVKFVTNEKYTRFPVYEETLDKIVGTLHVKDLLKYLSE 277

Query: 127 RSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
             D   F + ++LR  + VP+SK    + +E +  + H+AIVIDE+GG +G++T ED++E
Sbjct: 278 HEDKNEFDIHEILRDPLFVPQSKNTRALFREMKLTKTHIAIVIDEYGGTAGIITFEDLIE 337

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            I+G I  +  +ED+ + + +S   + +  L  ++D  +        E+ DT+ G ++  
Sbjct: 338 EILGNI-SDEYDEDEEEIQAISEDRYEIDGLIDLDDVEDLIHAGLPIEDYDTLSGFLLGQ 396

Query: 247 FGHLPARGET--IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            G  P   E+  +    Y+F+V   + + I +V V   ++ P  +
Sbjct: 397 LGRFPEADESIVVVYGHYRFEVLSYEDKIIERVLVTRIEEEPIEE 441


>UniRef50_C1F7E2 CBS/transporter domain protein n=1 Tax=Acidobacterium capsulatum
           ATCC 51196 RepID=C1F7E2_ACIC5
          Length = 425

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 87/277 (31%), Positives = 147/277 (53%), Gaps = 6/277 (2%)

Query: 18  FFSLLLSQLFHGEPKNRDE---LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
           F S+      H E +  DE   + ALI    +  +++E  R+++   ++  D+ VR++M 
Sbjct: 149 FLSIAALAEPHTEARAEDESEAVEALIEAGEEEGILEESDRELIRSAVEFGDKVVREVMT 208

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
           PR Q+  +  + TL++  +++ E+ +SR PV     DHI GI+ A DLL     DA   +
Sbjct: 209 PRPQLFAVPGSLTLEQFTEMLRENPYSRVPVYEGSVDHITGIIFAHDLLQITDEDARTRT 268

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +  + R A  VPESK+V+ +L+E + ++ HM +VIDE+GGV+GLVTIED+LE IVG I D
Sbjct: 269 VASLQRPASFVPESKKVNALLREMQMEKQHMRLVIDEYGGVAGLVTIEDLLEEIVGSITD 328

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIED--FNEAFGTHFSDE-EVDTIGGLVMQAFGHLP 251
           E+++ D     +    +  V     I               + +  T+ GLV +  G +P
Sbjct: 329 EHEDHDLAQVVREPSGSLIVPGTLEISTLEELLHEEVEIPQDMDATTVAGLVSELAGRIP 388

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
             GE ++  G +F++  +  RRI ++ +    +  Q 
Sbjct: 389 MAGEVVEQLGMRFEILASTDRRIERMRIARLPEDTQE 425


>UniRef50_C2BV08 HCC HlyC/CorC family transporter n=3 Tax=Mobiluncus
           RepID=C2BV08_9ACTO
          Length = 426

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 87/259 (33%), Positives = 155/259 (59%), Gaps = 5/259 (1%)

Query: 35  DELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDV 94
           ++L  ++   G+ D I++  R+M+  V ++    VR++M+PR  M+T++  +TLD+ L +
Sbjct: 169 EDLREMVDQMGEPDTIEDADREMIWSVFEMGRTLVREVMVPRVDMVTIESEKTLDKALTL 228

Query: 95  IIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--EAFSMDKVLRQAVVVPESKRVD 152
            + S++SR PVI ED D I GIL  KD+L  + SD      + ++ +R+A  +PE   VD
Sbjct: 229 FVRSSYSRVPVIGEDADDIRGILYLKDVLRRVNSDPAARQMTAEQAMREAKFIPEMNLVD 288

Query: 153 RMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTW 212
             L++ +   YHMA+++DE+G ++GLVT+ED++E ++GE+ DE+D  +  +       +W
Sbjct: 289 DTLRDMQQNSYHMAVLVDEYGLIAGLVTLEDLVEEVIGEVSDEHDHAEK-EPELQPDGSW 347

Query: 213 TVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSR 272
            V A   + D N+  GT   DE+VDT+GGL+ +A G +P  G +  ++G +     A+ R
Sbjct: 348 IVPARLPLVDLNDLLGTEIDDEDVDTVGGLLTKAVGVVPLVGASATVEGLELCAVEAEGR 407

Query: 273 R--IIQVHVKIPDDSPQPK 289
           R  +  + V++   +P  +
Sbjct: 408 RRQVSAISVRLVPPAPDEE 426


>UniRef50_B0PH06 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
           DSM 17241 RepID=B0PH06_9FIRM
          Length = 393

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 74/271 (27%), Positives = 141/271 (52%), Gaps = 8/271 (2%)

Query: 21  LLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI 80
            L+           +EL  ++    Q  +++E   D+++  +D  +   ++I+ PR  ++
Sbjct: 118 RLVKGPAAQPSVTEEELKYIVESIEQEGVLEEQESDLVQSALDFDEITAQEILTPRVDLV 177

Query: 81  TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLR 140
           TL    ++DE L V++++ +SR PV     D I G+L  +DLL  + +  +   +D ++ 
Sbjct: 178 TLDVEDSIDEALKVVLDAHYSRIPVYRGTVDSIIGVLQVRDLLKAVVTGRQT-QLDHLIS 236

Query: 141 QAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEED 200
             V V ++ ++  +L EF++++ H+A+V D++GG  G+VT+ED+LE +VG+I DE D E 
Sbjct: 237 DCVFVHKTMKISALLAEFKAKKLHLAVVTDDYGGTMGIVTMEDVLEQLVGDIWDESD-EV 295

Query: 201 DIDFRQLSRHTWTVRALAS----IEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGET 256
             DF Q    T+ V    +    +E+  E     F D + +T GG  ++  GH+P+ GE 
Sbjct: 296 HHDFVQTGPDTYLVSGDMNVFSMLEELEED-DRDF-DSDYNTAGGWALEMLGHIPSAGEQ 353

Query: 257 IDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
                 +  V   + +RI+ + V+      +
Sbjct: 354 YAFRDLRVTVVAVEEQRILSLRVEKLLPPDE 384


>UniRef50_C6D831 Putative uncharacterized protein n=6 Tax=Bacillales
           RepID=C6D831_PAESJ
          Length = 445

 Score =  281 bits (721), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 77/280 (27%), Positives = 147/280 (52%), Gaps = 4/280 (1%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDE--LLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           +  G   +   +      +   E  +  ++ DS Q+  I+      +  +    +   ++
Sbjct: 162 SATGLIRMFGLKAVKEHEEAHSEEEIQIILNDSFQSGKINNTEYGYVSRIFAFDEMLAKE 221

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAE 131
           IM+PR+ MI L  N ++ E +D+I +  ++RFPV +  KD+I G++  K L    + + E
Sbjct: 222 IMVPRTDMICLYTNNSMMENMDIIRKEQYTRFPVATGSKDNIVGMINTKQLFLEFQENKE 281

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
            F+  K++   + V E   V  +LK  + +R H+A+++DE+GG SG++TIEDILE IVGE
Sbjct: 282 -FNFQKLVHPVLAVSEVLPVKTLLKRMQQERVHIAVLMDEYGGTSGMITIEDILEEIVGE 340

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
           I DE+D ++  +  +L+ + + +    S++  +E  G     E+VDT+GG +   F   P
Sbjct: 341 IRDEFDTDERKEIEKLADNCYLLDGKVSLDHVSEITGVAIDQEDVDTVGGWLFTEFTD-P 399

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLD 291
             G+ +  +  +F +      RI +V + I +++ +   +
Sbjct: 400 KPGKEMHYENLRFIIREVGKHRIKKVELIIEEEADESTHE 439


>UniRef50_B2UP23 Putative uncharacterized protein n=1 Tax=Akkermansia muciniphila
           ATCC BAA-835 RepID=B2UP23_AKKM8
          Length = 443

 Score =  281 bits (721), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 76/261 (29%), Positives = 142/261 (54%), Gaps = 5/261 (1%)

Query: 32  KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDEC 91
            + DEL+ L+ +S ++  + +   ++ +  +++ D  V+D+M PRS++  +      +E 
Sbjct: 185 HSTDELMYLVEESERSRELTKQEAEISKNALELNDMCVKDVMTPRSEVDVMDLTAPFEEN 244

Query: 92  LDVIIESAHSRFPVISED-KDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKR 150
            ++  +S H+RFP++  D  D ++G +  KDLL  +    E   +  V R+  VVP++  
Sbjct: 245 WELARKSRHTRFPLVEGDHLDEVKGWVHVKDLLKLV--GRENPDLRSVRRELRVVPDTMP 302

Query: 151 VDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG-EIEDEYDEEDDIDFRQLSR 209
           +D +L  F  +  H A+V+DEFG   GLV ++D+LE IVG +I+DE+D+E+  +F +  +
Sbjct: 303 LDSLLTFFLKEHAHFALVVDEFGDSIGLVFLDDVLEQIVGDDIQDEFDQEEMREFVKTGK 362

Query: 210 HTWTVRALASIEDFNEAF-GTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAM 268
            T+ V    ++ D  +           V T+GG V+   G++P  GE + I  Y+  V  
Sbjct: 363 DTYAVNGAITLFDLADYLPEMDLDCPGVTTLGGYVISRMGYIPEEGEELRIGRYRAVVTG 422

Query: 269 ADSRRIIQVHVKIPDDSPQPK 289
           +D RRI Q+ +    +  + +
Sbjct: 423 SDGRRITQILLARLPEEQEEE 443


>UniRef50_C1A9F4 Putative uncharacterized protein n=1 Tax=Gemmatimonas aurantiaca
           T-27 RepID=C1A9F4_GEMAT
          Length = 439

 Score =  281 bits (721), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 68/280 (24%), Positives = 126/280 (45%), Gaps = 8/280 (2%)

Query: 14  NKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIM 73
           +      +L             ++ AL+    +  ++    ++++E    + D+ V  IM
Sbjct: 162 STNLILRMLGLGTVSEPGVTEQDIRALVEQGAETGVVQSAEQEIVENTFRLGDRTVESIM 221

Query: 74  IPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSD---A 130
            PR  ++ +    + D   D I ++A  RF V + + D++ G++ A+DL+          
Sbjct: 222 TPRPDVLWVDLADSADAVRDQIADAARERFLVCNGEIDNVIGVVFAEDLVLEAVKGVRID 281

Query: 131 EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVG 190
           +A +M ++ R  + VP    V  +L  FRS R H A+V+DE+GGV+GLV ++D+L  +VG
Sbjct: 282 DADAMRRLARTPIYVPTMMPVYELLATFRSARLHSAVVLDEYGGVAGLVALDDLLSALVG 341

Query: 191 EIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE---EVDTIGGLVMQAF 247
           ++       D   F +    +W +     +++          +    E+ T+GG VM   
Sbjct: 342 DVPS--APGDIAPFVKRPDASWDIDGTTPLDEIEARLDLEVPERERAEILTLGGWVMNRL 399

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
           G LP  G+    DG +  V     RR+ +V +       Q
Sbjct: 400 GRLPREGDEFQWDGRRVSVLRMKGRRVDRVLIGPLPKVNQ 439


>UniRef50_B3QY17 CBS domain containing protein n=1 Tax=Chloroherpeton thalassium
           ATCC 35110 RepID=B3QY17_CHLT3
          Length = 436

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 72/284 (25%), Positives = 134/284 (47%), Gaps = 12/284 (4%)

Query: 19  FSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQ 78
             +   +         +E+ AL     +   + +    ++E ++D  +Q VR IM PR+ 
Sbjct: 154 VRIKGMKSLSVSSLTNEEIKALAESGLERGELTDTEHLLIENILDFREQIVRKIMTPRAD 213

Query: 79  MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDA--EAFSMD 136
           +  +    + DE +++I     S+ P+  +D D+I G+L AKDL+ F  +    +     
Sbjct: 214 ICAIDTEASWDELVELIRNKKISKIPLYEDDLDNILGVLHAKDLVKFTNAKRQLKPEDWH 273

Query: 137 KVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEY 196
           K  R  + VPE++R+D +LK F+ +   +AIV+DE+GG SG+VT++DI++ I+GE+    
Sbjct: 274 KNARPPIFVPETQRLDDLLKTFQKKHTQVAIVVDEYGGTSGIVTLDDIIQEILGELA--A 331

Query: 197 DEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS--------DEEVDTIGGLVMQAFG 248
                 D++Q+    +   A   IE+  E                ++ DT+GG ++   G
Sbjct: 332 TPPSQADYKQIGTDCYRFDARIPIEEAFEVLNLPIHHPNKESDYSDDFDTLGGFILNLCG 391

Query: 249 HLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
            +P   + I  +    ++     +RI+ V +     SP     E
Sbjct: 392 GIPNEKQHIQYENLDIEIEKILGQRILSVIICTKQTSPPNPSQE 435


>UniRef50_B0MM65 Putative uncharacterized protein n=1 Tax=Eubacterium siraeum DSM
           15702 RepID=B0MM65_9FIRM
          Length = 425

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 75/288 (26%), Positives = 139/288 (48%), Gaps = 11/288 (3%)

Query: 12  ISNKKGFFSLLLSQLFHGE---PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQR 68
           +S        L ++LF  +        EL+A+I +     +++E  RD+++  ++  +  
Sbjct: 139 LSALFILLKKLANKLFGNKKEVTVTEQELMAIIDEIEDEGVLEEQERDLVKSALEFDETV 198

Query: 69  VRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR- 127
           V +I+  R  +I +  N+ ++   +  I   +SR P+     DHI G +  KD       
Sbjct: 199 VDEIITHRVDVIAVDVNEDIETVKETFINEEYSRLPIYEGSIDHIIGFVSQKDFFKKYLT 258

Query: 128 -SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
             D E F +  ++++   VP   ++  ++K+ +  + HMA+V+D++GG  G+VT+EDILE
Sbjct: 259 KKDDETFLLRDIMQEIHYVPHLMKISDIMKQMQKDKVHMAVVLDQYGGTLGIVTLEDILE 318

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFS-----DEEVDTIGG 241
            +VGEI DE DE        +S + + V    S+  F   +          D    T+GG
Sbjct: 319 QLVGEIWDENDEIIAP-VTFVSENEFNVNGDVSLTAFKRYWHNRTGDSPKIDGNAKTVGG 377

Query: 242 LVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            V++ FG +P   E++  D ++  V     RRI++V + +   S   +
Sbjct: 378 WVLELFGKIPETNESVTTDDFRITVLKVSERRIVKVRLTVIPKSENKE 425


>UniRef50_C1YNF1 CBS domain-containing protein n=1 Tax=Nocardiopsis dassonvillei
           subsp. dassonvillei DSM 43111 RepID=C1YNF1_NOCDA
          Length = 454

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 90/277 (32%), Positives = 140/277 (50%), Gaps = 13/277 (4%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
            G      EL  L+  + + ++ID +   M+  V  + D  VR++M+PR  ++   R   
Sbjct: 169 EGPFSTEVELRQLVDLAERGEVIDPEESQMIHSVFKLDDTPVREVMVPRPDIVFTSREAD 228

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR---------SDAEAFSMDKV 138
            D  L + + S +SR PV  ED+D + GI+  KDL+  +R          D    +   V
Sbjct: 229 ADAVLTLALASGYSRIPVTGEDEDDVVGIVYLKDLVYQLRDRWAAAAGTDDEVPLTAGDV 288

Query: 139 LRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDE 198
           +RQA  VP++K +D +L+E + QR H+A+ IDE+GG +GLVT+EDI+E IVGEI DEYD 
Sbjct: 289 MRQANYVPDTKPIDELLREMQQQRNHVAVAIDEYGGTAGLVTLEDIVEEIVGEITDEYDH 348

Query: 199 EDDIDFRQLSRHTWTVRALASIEDFNEAF-GTHFSDEEVDTIGGLVMQAFGHLPARGETI 257
           E       L      V A   + + +E F        +V+T+GGLV    G +P  G+  
Sbjct: 349 EIPP-VAWLDADRVRVTARLPLGELDELFPDRDLDVADVETVGGLVAFVLGRVPVGGDRA 407

Query: 258 DIDGYQFKVAMADSR--RIIQVHVKIPDDSPQPKLDE 292
           +  G +  +    SR  R+  V V+      +   +E
Sbjct: 408 EYAGLRLTLEGKSSRRSRMTTVLVERLPADAEGAPEE 444


>UniRef50_C7PAX6 Putative uncharacterized protein n=1 Tax=Chitinophaga pinensis DSM
           2588 RepID=C7PAX6_CHIPD
          Length = 433

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 71/279 (25%), Positives = 139/279 (49%), Gaps = 9/279 (3%)

Query: 15  KKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
                ++   +         +E+ ALI +   +  I+E  ++++E V  + D+ +  +M 
Sbjct: 158 TNFLVNIFNLKPTVDSNATEEEIKALINEGATSGAIEETEQEIIERVFHLGDRNITSLMT 217

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
            R+ ++ L  N   +     I ES HS +PV  ++ D+I GI+  KDL      +  A  
Sbjct: 218 HRTDIVWLDVNDPKEIIRSKIFESPHSVYPVCDDEIDNIRGIISIKDLYMAAADNVHA-- 275

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           +  ++++ + VPE+    ++L++F+  + H A ++DE+G   G++T+ DILE IVG++  
Sbjct: 276 LAPIMKKPLFVPENNSAYQVLEKFKETQSHAAFIVDEYGTFLGMITLNDILEAIVGDMP- 334

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG-----THFSDEEVDTIGGLVMQAFGH 249
           E  ++DD +  +    ++ V       DF   F        F ++E DT+ G ++    H
Sbjct: 335 ETGQDDDYEIVRREDGSYLVDGQIPFYDFLSKFDKEDWMAEF-EQEFDTMAGFILHHQEH 393

Query: 250 LPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQP 288
           +P  GE     G+ F++   D+ RI +V V+ P++  + 
Sbjct: 394 IPKIGEKFAWRGFTFEIVDMDAHRIDKVLVEAPEEDIEE 432


>UniRef50_B5JS09 Magnesium and cobalt efflux protein CorB n=5
           Tax=Gammaproteobacteria RepID=B5JS09_9GAMM
          Length = 398

 Score =  280 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 66/273 (24%), Positives = 129/273 (47%), Gaps = 8/273 (2%)

Query: 15  KKGFFSLLLSQLFHGEPK--NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
             G   L             N DEL +++ +      I    ++ML  V+D+    V DI
Sbjct: 123 ANGLLRLFGIDPKAQASLALNADELKSVLNEG---GTIPRTHQEMLANVLDLEQVTVDDI 179

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS-DAE 131
           M+PR++++ +      ++ ++ + +S H+R P   E  D+I G +  + +L  M   D  
Sbjct: 180 MVPRNELVGIDLEDDWEDIIEQVTQSQHTRLPAYRESIDNIVGFIHLRKVLFLMHEQDFN 239

Query: 132 AFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGE 191
             + + ++R A  VPE   + + L  F++++  + +V+DE+G + GL+T+EDILE IVGE
Sbjct: 240 RENFESLIRDAYYVPEGTTLTKQLLSFQNEKRRVGLVVDEYGDIQGLITLEDILEEIVGE 299

Query: 192 IEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLP 251
                D     +       ++ V    S+ D N+A       +   T+ GL+ +    +P
Sbjct: 300 FT--TDPLATKEIFPQHDGSFIVDGGTSLRDINKALNWALPTDGPRTLNGLITEHMEMIP 357

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHVKIPDD 284
             G ++ ++G+  +V +A++  I    +   + 
Sbjct: 358 ESGTSLKLEGHTIEVVIAENNAIKTARLFPTNH 390


>UniRef50_C1A944 Transporter n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A944_GEMAT
          Length = 432

 Score =  280 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 88/239 (36%), Positives = 136/239 (56%), Gaps = 2/239 (0%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           +  D R++L GV D  +    ++M+PR  +  ++R     E LD I  + HSR PV    
Sbjct: 186 VSRDERELLLGVFDFGETTAEEVMVPRVDITGVERETPWSEMLDRIRSAEHSRIPVYEGS 245

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFS-MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIV 168
            D I GIL  KD+LP + +D E       V+R  V +P SKR+  +L+EFR  R H+AIV
Sbjct: 246 IDEIVGILYVKDVLPAVLADEEPAEGWTSVMRSPVFIPTSKRIADLLREFRQARRHIAIV 305

Query: 169 IDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFG 228
            DE+GG +GLVTIED+LE +VGEI DEYD+E+           + V    +++D ++A  
Sbjct: 306 ADEYGGTAGLVTIEDVLEELVGEIGDEYDDEE-RLVESEEGTRYWVSGRLTLDDLSKALS 364

Query: 229 THFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQ 287
             F+ ++V T+GGLV++  G +P  GE++ I  ++  V     R+I +V ++   D+  
Sbjct: 365 HDFTRDDVSTVGGLVLELLGRVPKAGESLTIGPFRAIVERVVRRKIERVFLERVPDTTD 423


>UniRef50_C7HAW4 CBS domain protein n=2 Tax=Ruminococcaceae RepID=C7HAW4_9FIRM
          Length = 439

 Score =  280 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 75/278 (26%), Positives = 143/278 (51%), Gaps = 7/278 (2%)

Query: 19  FSLLLSQLFHG---EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIP 75
           +  LL    H    +     EL+ ++ ++  +  + +   +++   ++  D  V +I+ P
Sbjct: 149 WKKLLGHFVHSGEADTITEGELMTMVSEAENDGELTDRESELIRSAIEFDDVEVEEILTP 208

Query: 76  RSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSM 135
           R  ++ ++ +  L+E      ES +SR PV     D+I G++  KD   ++    +A  +
Sbjct: 209 RVDVVAVEDDIPLEELAQTFAESGYSRLPVYHGTIDNIIGVVHEKDF--YIARLKKATKI 266

Query: 136 DKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDE 195
           D ++   +    S ++ ++L+  R Q +H+A+V+DE+GG  G++T+EDILE +VGEI DE
Sbjct: 267 DDLVVPTLYTTGSTQISQLLRTLREQHHHLAVVVDEYGGTEGIITLEDILEELVGEIWDE 326

Query: 196 YDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLPARG 254
           +DE  + DFR+ S  +W V   AS++D  E       ++ + +T+ GLV +   HLP  G
Sbjct: 327 HDEVTE-DFRKQSDGSWLVSGSASVDDLYEELDLPEEEDIDSNTVNGLVQEKTCHLPKVG 385

Query: 255 ETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           +   +  Y   V     RR+ +V +     +   + D+
Sbjct: 386 DRFTLGEYDGVVTRTAKRRVTEVRLTPAAPAEDAEKDD 423


>UniRef50_D2RTA7 Putative uncharacterized protein n=3 Tax=Haloterrigena turkmenica
           DSM 5511 RepID=D2RTA7_9EURY
          Length = 467

 Score =  280 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 89/269 (33%), Positives = 144/269 (53%), Gaps = 8/269 (2%)

Query: 28  HGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQT 87
                 RDE+  +I    +  +++E+  +ML+ +    +  V+++M PR  M  + ++  
Sbjct: 188 ESPYVTRDEIQEMIESGEREGVLEEEEHEMLQRIFRFNNTIVKEVMTPRLDMTAVPKDAG 247

Query: 88  LDECLDVIIESAHSRFPVISEDKDHIEGILMAKDL---LPFMRSDAEAFSMDKVLRQAVV 144
           +DE ++  I+S H+R PV     D++ G++  +DL   L +  ++A+   ++ +++  + 
Sbjct: 248 IDEAIETCIQSGHARVPVYEGSLDNVLGVVHIRDLVRDLNYGETEADDLELEDLIQPTLH 307

Query: 145 VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDF 204
           VPESK VD +L E R  R HMAIVIDEFG   GLVT+ED++E IVGEI       +D   
Sbjct: 308 VPESKNVDELLTEMRENRMHMAIVIDEFGTTEGLVTVEDMIEEIVGEIL---KSGEDEPI 364

Query: 205 RQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPARGETIDIDGYQ 263
            QL   T  VR   +IED NEA      + EE +TI G +    G L   GE I  DG +
Sbjct: 365 EQLDDRTVIVRGEVNIEDVNEALEIDLPEGEEFETIAGFIFNRAGRLVEEGEEITYDGVR 424

Query: 264 FKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
             V   ++ RI++  ++   + P   L+E
Sbjct: 425 ITVETVENTRIMKARLRKL-EQPTESLEE 452


>UniRef50_B8FGS6 Putative uncharacterized protein n=1 Tax=Desulfatibacillum
           alkenivorans AK-01 RepID=B8FGS6_DESAA
          Length = 412

 Score =  280 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 78/269 (28%), Positives = 144/269 (53%), Gaps = 5/269 (1%)

Query: 18  FFSLLLSQLFHG---EPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMI 74
             S+LL++            DE+ +++    +   ++ED R M+  +   +D    +IM 
Sbjct: 145 LLSVLLAKPLKSSAQPIITEDEIKSVVTLGEEIGEVEEDERIMIHNIFRFSDLEAYEIMT 204

Query: 75  PRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFS 134
            R+ + +     T+++    ++   +SR P+    +D+I GIL AKD+L  + S  E  +
Sbjct: 205 DRTAIFSAPAEFTVEKVAKEVVLRGYSRIPIYENKRDNIVGILYAKDMLNALISGKEKAA 264

Query: 135 MDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIED 194
           + ++ R  + VPE+  +D +LK+F+ +R HMA+V+DE GGV GL+TIED+LE IVG+I D
Sbjct: 265 LKELARPVMFVPETILLDDLLKQFQKERVHMAMVVDEHGGVGGLITIEDLLEEIVGDIVD 324

Query: 195 EYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSD-EEVDTIGGLVMQAFGHLPAR 253
           E D+ + +   +  +    V+    +E+ N       S+ E+ +TI G ++     +P  
Sbjct: 325 ETDK-EQVMIHKTGKKKALVKGQTEVEEVNRVLHLGISEHEDFETISGFILSKMRKIPEP 383

Query: 254 GETIDIDGYQFKVAMADSRRIIQVHVKIP 282
           GE ++I     ++  AD+R I +V ++  
Sbjct: 384 GEELNIGDIVIRITKADNRHIEEVEIEKV 412


>UniRef50_UPI00016C05A3 CBS/transporter-associated domain protein n=1 Tax=Epulopiscium sp.
           'N.t. morphotype B' RepID=UPI00016C05A3
          Length = 282

 Score =  280 bits (719), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 69/266 (25%), Positives = 145/266 (54%), Gaps = 5/266 (1%)

Query: 23  LSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITL 82
           L +    +  + + +L LI +  +  +ID  +++M+EG++D   +   ++M PR +++ +
Sbjct: 16  LFRRQEKKSVSEESILRLIDEGSKEGIIDVTSKEMIEGILDFHGKNANEVMTPRPEIVAI 75

Query: 83  KRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRS---DAEAFSMDKVL 139
             ++ +DE +D ++E++ +R PV   D   + G+L  +  L  +     + +A  ++ VL
Sbjct: 76  DISKDIDEIIDFVLETSFARLPVYEGDVHKVIGVLHVQTFLGHLYKCQRELKAVILEDVL 135

Query: 140 RQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEE 199
            +  +VPE+K + ++LKE ++++ HMAI+ DE+G VSG+VT+ DI+  I+G+I+D  D+ 
Sbjct: 136 DKPYIVPEAKNIKKLLKEMQAEKKHMAIICDEYGDVSGIVTLNDIMLEIIGDIQD--DDS 193

Query: 200 DDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDI 259
           +D         ++ V  LA ++D N+        E  DT+ G V+   G +P     ++ 
Sbjct: 194 EDTAITLQDDGSYLVDGLAHLDDINKRLNIDLECEHYDTVSGFVIHLLGEIPKDLVKVNY 253

Query: 260 DGYQFKVAMADSRRIIQVHVKIPDDS 285
           +G  F++      R+ ++ +    + 
Sbjct: 254 NGITFEIKNIKGNRVEKLQIYKKKNE 279


>UniRef50_C0K042 Hemolysin-related protein n=1 Tax=uncultured bacterium 34R1
           RepID=C0K042_9BACT
          Length = 353

 Score =  280 bits (718), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 85/263 (32%), Positives = 146/263 (55%), Gaps = 9/263 (3%)

Query: 27  FHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQ 86
              +  + ++L   +  S        D ++ML G++   D+ V +IM PR  ++ L    
Sbjct: 88  KKADDISVEDLSRALEASDLKST---DEKEMLRGILTFGDKTVSEIMRPRVDVVDLDIEL 144

Query: 87  TLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVP 146
             D+ +  ++E+ +SR PV  E+ D+I+GIL AKDLLP++    + F    ++R A  VP
Sbjct: 145 GFDDVVKAVVENGYSRMPVYEENPDNIKGILYAKDLLPYIGKKDDTFKWQSLMRPAYFVP 204

Query: 147 ESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQ 206
           ES+ +D +L++FR ++ HMA+++DEFG   G+ T+ED+LE IVG+I+DEYD E+   F +
Sbjct: 205 ESRMIDDLLEDFRKKKIHMAVIVDEFGCTQGIATLEDVLEEIVGDIDDEYDTEEK-YFTR 263

Query: 207 LSRHTWTVRALASIEDFNEAFGTH---FSD--EEVDTIGGLVMQAFGHLPARGETIDIDG 261
           ++ +T+   A   ++DF EA       F+D  +E +T+ GL++   G      E +    
Sbjct: 264 VAENTYIFDAKTPLDDFFEATCIDENNFADHLDEAETLAGLLLSLKGDFLKEKEELKTAP 323

Query: 262 YQFKVAMADSRRIIQVHVKIPDD 284
             F V      RI +V V++  +
Sbjct: 324 CTFTVLKVKKYRIAKVKVEVKPE 346


>UniRef50_A8U4Z8 Hemolysin n=1 Tax=Carnobacterium sp. AT7 RepID=A8U4Z8_9LACT
          Length = 448

 Score =  280 bits (717), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 86/288 (29%), Positives = 149/288 (51%), Gaps = 6/288 (2%)

Query: 10  DTISNKKGFFSLLLSQLFHGEP--KNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQ 67
             +S        L    F  E     RDE  A +  S     ID D   ML+G++ +  +
Sbjct: 158 KLLSFSTNILKRLTPIDFTEEKEKMTRDEFRAYLEHSQIAGAIDPDEFTMLKGILSMDTK 217

Query: 68  RVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMR 127
             R+IM+PR+    +   +     +  +++  +SR PV  EDKD I GI+  K+LL   R
Sbjct: 218 MAREIMVPRTDTFMIDYKEGSAVNIPQLLDIPYSRVPVYLEDKDSIIGIVHVKNLLKASR 277

Query: 128 SDA-EAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186
           +   +   +  +L + + VPE+  +D +L E R  R  +A++ DE+GGV G+VT+ED+LE
Sbjct: 278 TTKIDDIDLKDILNEPLYVPETIHIDDLLYELRRTRNQLAVLNDEYGGVVGIVTLEDLLE 337

Query: 187 LIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQA 246
            IVG+I+DEYDE  ++   ++S   + V     +  FNE FGT     +VD+I G  +  
Sbjct: 338 EIVGDIDDEYDETYNM-IEKVSESIYLVDGSTQLSKFNEYFGTEIESNDVDSIAGYFITQ 396

Query: 247 FGHLPARGE--TIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE 292
           +G++P  G+   ++ + Y  K    +  R++ ++V+  + +   + +E
Sbjct: 397 YGNIPQPGDNANVEYENYLLKSNKVEGSRLVSLYVERLNTTNDDEENE 444


>UniRef50_B2S3N8 Hemolysin n=5 Tax=Spirochaetaceae RepID=B2S3N8_TREPS
          Length = 265

 Score =  280 bits (717), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 81/241 (33%), Positives = 142/241 (58%), Gaps = 2/241 (0%)

Query: 50  IDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISED 109
           ++E+ +DM+ G++D++D  VR++MIPR  +  L+ + + +  ++ + ES HSRFPV  + 
Sbjct: 21  LNEEKQDMIRGIVDLSDTSVREVMIPRIDVDFLELSMSGETLVEKVTESGHSRFPVYEQT 80

Query: 110 KDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVI 169
            D++ G+L  KDL+  +    +   ++++LR+   VPESKR+D +L+EF+ +  H+AI +
Sbjct: 81  IDNVVGVLYVKDLIK-LFGRPQEVRLERLLRKPFFVPESKRIDSLLREFKRRHVHIAIAV 139

Query: 170 DEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGT 229
           DE+GGVSG+  +EDI+E IVG+I+DE+D E + D   L +  W   A   +ED +E   T
Sbjct: 140 DEYGGVSGIACMEDIIEEIVGDIQDEFDHERE-DIEPLGQGVWLCDARVDLEDLSECLHT 198

Query: 230 HFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPK 289
            F  +E  T+GG V   FG +P + E +    + F +   ++ +I  + +          
Sbjct: 199 VFPSQEFGTLGGFVFNLFGKIPVKYEKVSWGAFDFIIQDMEAHKINTIKIVSVLRGDSEP 258

Query: 290 L 290
            
Sbjct: 259 A 259


>UniRef50_O07589 UPF0053 protein yhdT n=119 Tax=Bacillales RepID=YHDT_BACSU
          Length = 461

 Score =  280 bits (717), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 84/273 (30%), Positives = 142/273 (52%), Gaps = 8/273 (2%)

Query: 14  NKKGFFSLLLSQLFHGE--PKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRD 71
           + +    +   +         + +EL  L+ +S +N  I+      +  + +  ++  ++
Sbjct: 160 SARLLCGMFGLKPASEHDGSHSEEELRMLLSESLKNGEINPSEYKYVNKIFEFDNRIAKE 219

Query: 72  IMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAK----DLLPFMR 127
           IMIPR +M  +    T+ E L+V+++  ++R+PV   DKD + G++  K    DLL    
Sbjct: 220 IMIPRKEMAAVSTEMTMAEMLEVMLKEKYTRWPVTDGDKDSVLGLVNTKHLFSDLLFMTE 279

Query: 128 SDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILEL 187
            +    ++   +R  + V E+  V  +L + + +R HMAI+ DE+GG SGLVT EDILE 
Sbjct: 280 EERMKMTIHPYVRPVIEVIETIPVHDLLIKMQRERIHMAILSDEYGGTSGLVTTEDILEE 339

Query: 188 IVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAF 247
           IVGEI DE+DE++    ++L    + +     I+  N   G     E+VDTIGGL+++  
Sbjct: 340 IVGEIRDEFDEDEQPLIQKLGDGHYVMDGKVRIDQVNSLLGASI-QEDVDTIGGLILKEN 398

Query: 248 GHLPARGETIDIDGYQFKVAMADSRRIIQVHVK 280
             +   GE+I I  Y  KV   D R I Q+ +K
Sbjct: 399 IDI-EAGESIRIGSYTIKVLKMDGRLIKQIDIK 430


>UniRef50_UPI0000510515 magnesium and cobalt efflux protein n=1 Tax=Brevibacterium linens
           BL2 RepID=UPI0000510515
          Length = 442

 Score =  280 bits (717), Expect = 5e-74,   Method: Composition-based stats.
 Identities = 74/268 (27%), Positives = 138/268 (51%), Gaps = 4/268 (1%)

Query: 15  KKGFFSLLLSQLFHGEPK--NRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDI 72
                     +         + +EL +L+R S +  ++DE T D+LE  +  +++   D+
Sbjct: 160 ANKILLSFGIEPQEEGSVGRSPEELTSLVRHSAEEGMLDEQTADLLERTLSFSERTAEDV 219

Query: 73  MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132
           M PR++M ++ ++ T    ++   E+  SRFPV  EDKDHI G++  K       ++ + 
Sbjct: 220 MTPRTRMSSVVKDTTARAIIEQARETGFSRFPVAGEDKDHIVGVVHVKQAFAVPLANRDD 279

Query: 133 FSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEI 192
                ++ +   +PE+  +D +L E R+Q   MA+V+DEFGG +G+VT+ED++E +VGE+
Sbjct: 280 AYAGGLMTEVTEIPETLLLDPLLMELRAQGLQMAVVVDEFGGTAGVVTLEDVVEELVGEV 339

Query: 193 EDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDE-EVDTIGGLVMQAFGHLP 251
            DE+D    +  R     TW V      ++ +   G    ++ + +T+ G V++  G +P
Sbjct: 340 ADEHDRMR-VAARPARDGTWIVPGQLRPDEVSSTVGLQIPEDSDYETLAGFVLKELGRIP 398

Query: 252 ARGETIDIDGYQFKVAMADSRRIIQVHV 279
             G+ +  D    +V     RRI ++ +
Sbjct: 399 EPGDQVRTDDALIRVERMHGRRIERLRI 426


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.314    0.201    0.648 

Lambda     K      H
   0.267   0.0614    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,566,710,946
Number of Sequences: 3077464
Number of extensions: 170603095
Number of successful extensions: 428680
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 2271
Number of HSP's successfully gapped in prelim test: 2238
Number of HSP's that attempted gapping in prelim test: 417118
Number of HSP's gapped (non-prelim): 6623
length of query: 292
length of database: 1,040,396,356
effective HSP length: 127
effective length of query: 165
effective length of database: 649,558,428
effective search space: 107177140620
effective search space used: 107177140620
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (20.9 bits)
S2: 94 (40.2 bits)
