>ss_pred
CCCCCCCCCCEEEECCCHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCEEEECCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEECCCCEECCCCCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
>ss_conf
9888767752686424478852976567568998999870857576855699899999999986406894799999999886163688999986387650605477279999987753047842698426800689998608752742999836420103335786642215889999987349987560346783278827875186214764656780568999999999999868980697202778216999999861398260685116999999999776750882211069997466889999999999998749994674236999828961648877888678763035466420246455588899996259989998058888869999998760489978985068996344798999961399899995787777103893746664203465668989888616500588999999999986279665258751588457565459999999999998698778996689999997267874768623679
>batch____
MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIISQTQREGLSEEAARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGMVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI
>UniRef50_Q6FFL8(4-563:566) NAD-dependent malic enzyme n=84 Tax=cellular organisms RepID=MAO1_ACIAD  E=0 s/c=1.41 id=68% cov=99%
-ETNTNKH-PLYIPYAGYTLLELPLLNKGSAFTQEERSHFNLHGLIPHVIETIEEQSQRSYQQYGAFNDDINKHIYLRNIQDTNETLFYRLINDHLEEMMPIIYTPTVGEACQRFSDIYRRHRGIFISYPDREHIDDILQNVSKRNVKVIVITDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPITIDVGTNNQQLLNDPIYMGWRQPRISGDEYYEFIDQVLTGIRRRWPHALIQFEDFAQKNAMPLLTKYRDKFCCFNDDIQGTAAVSVGSLIAASRAAGKQLKDQTITFLGAGSAGCGIAEQIVAQMVAEGLTDAQARARVYMVDRFGLITENQPNLLDFQRKLAQKAEVVSDWGNVEEVISLLDVVKNAKPTVLIGVSGQPGLFTEEVIRTLAENCERPIVMPLSNPTSRVEALPSDVIQWTNGRALIATGSPFAPVNYQGKLYNISQCNNSYIFPGIGLGVIASGAKRVTDNMLMASSNALADCSPLLQNPNADLLPAIADIQDVSKRIAFKVAKAAIEDGVALNMSDEVLLQNIEKEFWKPKYRGYKR---
>UniRef50_A5IBD3(15-569:574) Malate oxidoreductase n=12 Tax=Legionellales RepID=A5IBD3_LEGPC   E=1e-153 s/c=0.98 id=46% cov=98%
----------LYIetSLCGKPLLTTPQLNKGTAFTQEERKDFGLLGKLPHRVETLDEQVKRAYLQYSSYTTRLQQHIYLNNLHDKNQIVFYKLLSRHLGEMLPIIYTPIVGAAAKRFSHEYRQPRGLYIAHSDKNQLEEIINNRSNPDIDLVVVTDGEGVLGIGDQGIGGMDIPVAKLMVYSLCGGIDPTRTLPIFLDVGTNNQELLNDPMYLGCRHPRIKSSEYDDFIKTFVNEIHKQFPNAFLHWEDFGRGNARRILDQFQDELCTFNDDIQGTGAVTLAAILAACDVTGLPLHEHRIVVFGAGSAGTGISDQIVDAMVKSGLSLTDAYDRFWLIDKQGLLLATDQELTDAQKPYARNPIDIQSWEINNKQHpSFTDTIRHVKPTILIGCSAQTGAFSQDIVETMSTACERPIIFPLSNPDEKCEAQPSDILAWSKGRALIATGTAFAPIEYQNRMVQIAQCNNALVFPGIGLGVLAVSASRLTKDMILAAAQTLSKFAPSKKDSFLPLLPSLDNAQIVAKEIAIAVAQCAIDSGYAQKNQDKDLPRLIDELFWEPRYLPFRK---
>UniRef50_Q0AIF8(2-536:536) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=2 Tax=Nitrosomonas RepID=Q0AIF8_NITEC  E=1e-128 s/c=0.86 id=44% cov=94%
--------KSLY----GKTLLNDPVQNKSTAFTREEREHYGLQGLLPYGVTDIKKQQQRVLANLRNKSSNIEKYIYLNDLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDRGEIISRLKNWPETDVQIIVVTDGERILGLGDLGANGMGIPIGKISLYVACAGIYPDRCMPVMLDVGTGNQALREDPLYLGYPYPRLVGQDYLSLVDEFVEAVQHRYPDALIQFEDFSSRNAFTLLDRYAASVRCFNDDIQGTAAVTLAGIYASCRITHKSFADLKIMLLGTGSAATGVAELLLPAFKAAGLGEAEAHSRISFVDRRGLVTAAHELIKPRICPFVSERE----------AMSFVDAITAIQPDVLIGATGTAGAFNEAVIREMARCQERPVIIALSNPTSHTECTAEQAYRWSEGRVIFASGSPFAPVTFNKRTHYPAQGNNVYIYPGIGLGVMASRARLVVERMFLVAAEELANR---VLSGEierGSIYPDIARVRDISQGIAIKVCQVAWQDSLAGGNLPEDLEANVQALIYEPGY--------
>UniRef50_Q99KE1(11-562:589) NAD-dependent malic enzyme, mitochondrial n=98 Tax=Eukaryota RepID=MAOM_MOUSE  E=1e-119 s/c=0.78 id=41% cov=96%
--------RRVHLKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACCQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIQPEKCLPVCIDVGTDNMALLKDPFYMGLYQKRDRSQLYDDLMDEFMKAITDRYgRNTLIQFEDFGNHNAFRFLRKYQQKYCTFNDDIQGTAAVALSGLLAAQRVINKPVSEHKILFLGAGEAALGIANLIVLSMVESGLSEEEAQRKIWMFDKSGLLVKGR------TASIDSNQEPYAHAAPESIPATFEDAVNKLKPSVIIGVAGAGPLFTHGVIKAMASINERPIIFALSNPTAQAECTAEDAYTLTEGRCLFASGSPFEPVKLQDgRVFTPGQGNNAYIFPGVALAVILCEARHISDTVFLEAAKALTTQLTDAELAQGRLYPSLANIQEVSANIAIKLAEYLYANKMAFRyPEPEDKARYVRERIWRSNY--------
>UniRef50_C8V365(14-580:581) Malic enzyme n=22 Tax=cellular organisms RepID=C8V365_EMENI   E=1e-119 s/c=0.76 id=42% cov=98%
-------QGPIKCPYKGAALLGNANYNKGSAHSERERREFNLHGLLPPNIQTLDEQVERAYQQYKSRPDDLAKNTFMASMKSQNQVLYYRLLQTHLKEMFSVIYTPTEADAIQNYSRLFRKPEGCYLSIRDHgeKEIDECFANFSgGDDVDYIVVSDGEqwQILGIGDQGVGAILISVAKLVITTACAGIHPSRQLPVVLDCGTNNEELLNDKLYLGLRQRRAQGEEYDKFVDKFVRMARKRFPNAYIHLcsEDFGLQNAKRILDRYRSQLPCFNDDIQGTGCVTLAALMAGLHVSNVKLKDVRVVCYGSGSAGTGIADQISDAIATEaGFSKSDALKQIWCIDKQGLLLKSQGDALTASQKYFAKEDN--EWPEGQDI-DLYSVIKHVKPHVLIGTSTKPGSFTEETIREMAKHVDRPIIFPLSNPTRLHEAQPQDITKWTDGKALIATGSPFPPVEYNGTKTEIvsAECNNSTAFPGIGLGAVLSRASRLSEKMVVAASKALAAKAPALEDPNKPLLPDVENVRELSLNVAKAVIQTAVKEGLAqeegIPEDEKDLEDWIRAQMWEATYRDLEK---
>UniRef50_Q6TU48(8-539:544) NADP-dependent malic enzyme n=2 Tax=Amoebozoa RepID=MAOX_DICDI   E=0 s/c=1.55 id=43% cov=94%
-------------------ILRNPSANKGTGFNNEEREKLGLKGLLPPKVESLQEQSDRALSQFTSFNTNLERYIFLNCLRDRNETLFYYLLSNNLELMMPIIYTPTVGEACQKFGNEFRFAQGMYFASQDKGNIRAMMDNWPAEGVDIIVVSDGSRILGLGDLGTNGMGIPVGKLQLYVAGAGFCPTRTLPVIIDSGTNTKKYLEDKYYLGERHPRIPDSEYYPLVDEFLAAAFNKWPKVIVQFEDISNDHCFNLLDEYRNKYLCFNDDIQGTGSVILSGFINAVRSVQKPIKEHRMVFLGAGSAGIGVADCIMSLFDEAGVSKEEARKSFWFVDSKGLITTTRGDELTSQKK------QYAREDYTYQLKSLLEVVRDVKPTAIIGLSGIGGSFSQEVIEEMAKHVEKPIVFALSNPTTNAECTAEQAYQWTDGRCIFASGSPFKPVEYKGKTFVPGQGNNMYIFPGLGLAASVCEAKHVTDAMIITAAKTLASFVEDSEVLTGKIYPGLQHIREISTRIAVKVIEKAYEEGMAQLPRPDNIEALVKSRQYVPSY--------
>UniRef50_B8FJN7(52-597:609) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=6 Tax=Bacteria RepID=B8FJN7_DESAA  E=0 s/c=1.51 id=45% cov=97%
-----KMRRLENIPH-GAAILRDPYLNKGTAFTKEERELLGLNGLLPPRVHTMEAQVMRILENLRKIENDLDKYVYLNSLSDRNKTLYYRVLMENIEELMPVVYTPTVGQACQEYAHIFRRSRGIYISAEDKGRVADVLRNWPQKDVRLIVVTDGERILGLGDLGADGMGIPVGKLALYSACAGIHPSLSLPVTIDVGTENKELLEDPLYFGLTQNRLRGDAYDELLEEFVVAVQQVFPRCLIQFEDFSNANAFRLLDKYRDEVLCFNDDIQGTAAVALACIYSALRYTGGSMADQKFLFLGAGEAGMGAANLIVSALVDEGVSEEKARQCCWFVDSKGLVVKSRNNLNAHKREFAHDHAPAS---------SLLEAVESVRPTAIIGVSGQGKMFTKEILERMADYNEKPIVFPLSNPTTKAECTAEDACQWTDGRAVFASGSPFKPFTYAGEKRFPAQGNNVYIFPGVGMGCMACWSRKVTDEMFLAAARVLSGLVTPEEQKQGMLLPPLTRIREVSLEIASAVAEVAYDQGLATHPRPSSLETHIASLMYIPTYMDY-----
>UniRef50_B7FRZ7(81-629:638) Malic enzyme n=3 Tax=stramenopiles RepID=B7FRZ7_PHATR   E=0 s/c=1.47 id=44% cov=96%
---------PIRISVRGTDILLDPLYNKGTAFKTGERDRLRFRGMLPHRIMNIHLQKERFLQALRAEDSNIRKNVMLEDLHDRNETLYHRVLVDHIEEMAPYIYTPTVGQACMEFATRYRRPRGMYFTEEDRGHMAAMVYNWPHRDVHVICVTDGSRILGLGDLGANGMGIPIGKLALYCAAGGIAPHRVLPVVFDAGTNNEALLQDKYYLGVQRKRLKGAAYFRMMDEFMDAVRFRWPNVLVQFEDFSSEVAQTLLDRYRDDHLCFNDDIQGTGATTLAGVLGALRAKGeevTSLGDQRIVIAGAGSAGIGIAQVLMQAMEEQGRTPEEAKNAFYILDQNGLLgTDRANDLNAEQRVFVRSADN---------NLSLMDVVKKYKPTILLGVTTVGGLFTGDLIREMHSSCERPIIFPLSNPTNKAECTAEQAYEWTNGQCIFASGSPFDTIEFEdGRVFYPSQCNNMYVFPGLGLGASVCGAQKVTDRMLYVAAETLANFVSKKDMEEGRLFPQLTRIREVSHRIAVAVVEEALREGLATKVKPAdanDLDSFVGRKMYFPEYVP------
>UniRef50_A8IGQ2(14-558:558) Malic enzyme n=16 Tax=cellular organisms RepID=A8IGQ2_AZOC5   E=0 s/c=1.39 id=37% cov=95%
---------------SGLALLHEPNQNKGTAFSRDERQALGLEGLLPHAVESLDRQVERVLSHLDTKMDDLERYIYLIGLEDRNETVFYKTIMSDPKRFIPILYDPTVADACLTFGNLYRRARGMYITRHMKGRIAEVLRNWPRKDVRFICVSTGGRILGLGDIGANGMGIPIGKLQLYTACAAVPPDCLLPVLFDIGTTNESLRADPFYLGTREPPLAEAELDELTEEFITAVQEVFPDCCVHFEDWKGTDAIRMLDRYRDRILTYNDDIQGTASVALAGIAAAMNITGGKLSEQRVLFLGAGSAGIGISKLIAAEMQTKGLTAEEARARIALFDVNGLVEASRTDLTEAQKLYAHKGPPTKDF---------VKFIKEFKPTVLIGVSTKAGAFNQQVVEAMSQLNERPVIFALSNPTTKAECTAEQAYTWSKGKALFAAGVQFDDVEFEGKIYRPGQANNFYIYPAIGLATYVARPKRLTDECFIVAAHATADQVGPALCAKGMLYPSQDQILETEVTTATRIVEYMFDAGLAQVERPRDIRAWIEGQLYKPHY--------
>UniRef50_A4RQC9(7-543:549) Malic enzyme n=2 Tax=Ostreococcus RepID=A4RQC9_OSTLU   E=0 s/c=1.40 id=41% cov=94%
----------------GTAVLDSPSLNKGTGFTFTQRERLGLRGLLPRKYETVEIQVKRAWTQLCAFEEDMNRYIFLENLHMQNERLFYRVLVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFSRLDSGVMRRMLDNWPSPETEIIVVTDGGRVLGLGDLGTNGMAISVGKVSLYVASGGFDPAKSMPVCLDLGTSNVALRAHDFYLGADEPRLTGDAHLAVVTEFCLAVKDKWPNCLIQFEDFKTEDAFRILDHMRHKVLCFNDDIQGTGATILAGLINALRAQGTPTKDARIIFFGAGSSAIGVSTQIIQLLMSEGLSEEDARQSIYLMDSKGLITDQREDfagLSDQKKQFAQ--------VGVEPCDDLGALIQRVKPHALFGLSGFGPVFTREHIEMLCDHIGKPIVFPLSNPTSKAEITALDAYTWSKGKCLFAAGSPFDPVVIDGKTYTPGQGNNMFIFPGVGFAAVSIQAEYVPDSFFLCAARALAAIVPDEDVRSGTIYPSVSIIRDISRQVAVAVANHAYDVGVAkLYPRPGDMNAFIAERMYFP----------
>UniRef50_Q9HE50(462-1023:1023) Malic enzyme n=13 Tax=Eukaryota RepID=Q9HE50_NEUCR   E=0 s/c=1.33 id=41% cov=95%
----------------GYQVLNQPHWNkvadfrispKGTSFTPEERVAKNLTGLIPHVMEDSEKQVERALKMIRTRQTDIDRYLYLSTIKSQNVDLFYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTILRNWPYPQPEICVVTDGSRILGLGDLGVNGVGIPIGKLALYTAAAGIHPDKTLPIVLDCGTANETNLKDPLYLGLRQKRIPVAEQQEFMDEFMEAAAEVFPDMVVQFEDFESEKAFNYLDRYRDQYKCFNDDIQGTGAVVLAGYIGAVNLSNVPIEEQRLVFMGAGSAGVGVAKQLVEYYTKRGLSEQQAKDKFWLVDTKGLVTKDRGDKLAEHKKYFARTDN-----NGHQFRTLEEVIEYVKPSALVGLTATHGVFTESVVRALKASVDagglgrRPILFPLSNPLTKAECTFKEAIDWTDGTVLFASGSPFSSYTTNGVTYHPNQGNNVYVFPGIGLGAILAKATRVTDDMIYTSAAALANSLNADEVKQGLIYPRIDRVREASVIVAREVMKSARREGVSTLPeeqwleweewGDVDLERYIKQHIYDPKF--------
>UniRef50_Q86NT5(56-580:610) Malic enzyme n=10 Tax=Drosophila RepID=Q86NT5_DROME   E=0 s/c=1.40 id=39% cov=93%
--------------------------NKALAFTLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYERLYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPmRRSVKAICVTDGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSLHEDPLYIGLRDERLKGDEYVCFVDEFMEAVVSTFGDqTLIHFEDFATPNAFMFLNRYQHCYCHFNDDIQGTAAVGLGGLLGIQRITKKPLEEHVIVFAGAGSAAMGIAYLLKMELMSRGLSEADAAKNIYFYDQDGVLTTARKSIPDILCVFAKNMKETK---------SLETLVEQVKPSIIMGATSAPGLFTEKIIRTMAASHERPGIFAFSNPTIKSECTAEQAYKFSDGKAIYSAGSPFPPVEFNGKRLTPGQANNCFAFPALVLATMTVLATRMPDEIFLLAAHELAEFPTNEEMQSGRIYPLVKQANEVAYKIGVKVAKYLIENGYAKRNlEPEDVEEYIEKNSYKLTY--------
>UniRef50_C0NM72(37-575:618) Malic enzyme n=5 Tax=Ajellomyces RepID=C0NM72_AJECG   E=0 s/c=1.36 id=44% cov=90%
-------------------------------------------GLTPPRVESYETQKTRCLRQLAVKATAIDKFLYLSTLRRNNVHLFYRLVVDHLKELTPLIYTPVVGEACQRWSEIYQQPEgclGMYISYEDRGNIAAVIQNWPQPHVDITVITDGSRILGLGDLGINGMGIPIGKLALYTACAGIRPEATLPLTLDLGTSNKALREDPLYLGSRRNKVSPEQELEFMDELMTALTEKWPGhslllclankilsVVIQFEDF--KNPFPALERYRHRFTCFNDDIQGTGAVILAGVINAVKQSGIPAKEHKAVFLGAGSAGVGVAKQIVDFFVREGMTEDEAKACFYLVDTKGLVTADRGDQLASHKVYFARTDN-----QGLQLKTLSEVVDHVKPTMLMGLSTLGGVFTPEILRSMASFSKRPIIFPLSNPSANSECDFESAIIHTDGQALFASGSPFQPFSYKNsagqiKTYYPGQGNNMYVFPGIGLGTILSKAVEVTDSMIYASGEALSKTLTSEELEHGLLYPDLTRIRDVSVIVARGVIRAAQEAKVDRETGIRDLSNadmdaWIRSKMYAPH---------
>UniRef50_Q5KEY3(45-626:629) Malic enzyme n=1 Tax=Filobasidiella neoformans RepID=Q5KEY3_CRYNE   E=0 s/c=1.19 id=44% cov=98%
---------PIRTNLRGSALLNTPRLNKGAGFTREERQIFGLEGFLPYDVHSLEKQCLRAYNQLCKQPSVILKHAFLASLRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFPNQDGMRAQLeghltdvnrtadvaydSNKPDDAIDLVVVTDAEAILGIGDQGVGGITISTSKAALYTLGAGINPNRILPVVLDCGTDNHALFSDPLYMGWKRTRIRGKNYDQFIDRFITNCRELFPNAIIHFEDFGMANAYRLMEKYKN-IPMFNDDIQGTGAVALAALLSAIKVAGSRLSDQRIVIYGAGSAGMGIADQIKDgLMILEGLNKDEAARRFWCVDRNGLLVESMGNgLRHSQMPYARPDAEVEHWnkeDEDRNGIWLMDVIKNVKPTVLIGTSTHSRAFSEELVREMGKHVERPIIFPMSNPTALCEVDPADALAWTENRALVATGSPFPPVQLgNGQEYIVAQTNNALIYPALGLGAILARSKTISNSMLMAGVNSLASLSPALSNSEASLLPDLADVRKVSVDVAAAVVRQAVEDGNAydentikyvKGKGDVSLEEYIRSRMWDAVYRPLE----
>UniRef50_C1FFL1(1-524:525) Malic enzyme n=2 Tax=Micromonas RepID=C1FFL1_9CHLO   E=0 s/c=1.25 id=36% cov=92%
-----------------------------MAFSEEERYKMHLLGLLPPGKFTQNTQVKRVMRVIRGLSDPTEQHLHLLGLLERNERLFYRVLVEHQDELFPIIYTPTVGRVCKKFSEVFYGPRALYITSRDKGRIYDILKNWPEKHLKLLVVTDGERVMGLGDLGVQGIGVAVAKSCLYTSMGGLDPADVLPVCIDVGTNNESLLNDPLYIGQKTRRVEGEAYDELMDEFVDAVKLRFGdRVIVQFEDFSNQNGKRLQERYATRAATFNDDISGVAATTLAGVIASLPKTGmKKVGDHTFLVAGAGETGTGIGEMIAEYIaQDEKIPINEARKRVWMVDSKGLITRSRAEK---EEDLALHKLPWAHG-GKRECATVLEAVEAVRPTALIGA----------VLQKMGECAQAPLVFALSRPENIAECTAKEAYDATGGRCVFAGGCQVEPFVHAGRGVEIRASTSAYVFPGFAYGLTLADAHRVRTPMWLEAAEAVASMVTEEDLGKGAVYPRMAKIREVSAMVAARVAMKCHEMGVAsipgKPPSSAKMLADAKRLMYNPAYRCY-----
>UniRef50_C1EDY1(149-665:716) Malic enzyme n=1 Tax=Micromonas sp. RCC299 RepID=C1EDY1_9CHLO   E=0 s/c=1.25 id=39% cov=91%
----------------GYANLHDPRVFNGLATP--DRTNRSLDGLIPAGEAPPDVEVARAAAALEACDTPMQKYRQLVSLQNTDETTFYALLELKTAELLPVLYTPTVGDACLQFGTLTQRPPGLYVSLENIGNVRALVDNWPANDVRIAVLTDGERILGLGDQGVNGMGISAGKSMVYAAC-GIKPGWLLPVQVDNGTNNTKLLADPLYVGTRRERVRGEAYDRLLDETVQAIQGRYGaRTVIHWEDFAPRNAFRNLQRFRTKgAITYNDDIQGTAAVTVAGILASLRVTKRALREQRVLFFGAGQANIGAAELLVRALTEEGVDESLARSNVFLFDSKGLVVDGR----PAEYTISDDKAPFAAKVGTPFTSSLEEAVKSVRPTALVGAAAQPQVFTKRVIESMCAFNPRPVIFALSNPTSKAECTATQAYEWSKGKAVFASGTLFAPVNYKGVRFAPGFANNAFIFPGVALGSLASGASSVTDAMFLAAARSLASQVSEENLAVGAVYPPTSTIREAAVVVGAAVAAAADEGGVA-----------------------------
>UniRef50_A4RZU1(4-530:539) Malic enzyme n=3 Tax=Mamiellales RepID=A4RZU1_OSTLU   E=1e-180 s/c=1.20 id=39% cov=87%
--------------------------------------------------------VRRAMEAFRAIADPLERYVYLRELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYITADDAGRVGAKLRgHWdraaaarararegldgeaakrrgvdrrarADDGVAVAVVTDGERILGLGDLGAGGMGISEGKILLYTVCAGVRPSACLPVCLDVGTNNQRLLDDPNYKGLRRTRLKGEAYDALVDEFMREMRAWQPRCLVQFEDFGNANAFRILEKYRTTGPCFNDDIQGTAAITLAALLSSLRATKGKLEDQKVLFYGAGEAGVGIGELIAMAMEKTGMSHKEAMERCYFMDSKGLVCKSRlDGLQPHKVAFAHDVEYQPD---------LLSAISAVKPTALIGVSTIGGAFTEDVVKEMCALNERPIIFPLSNPTSKSECTFEQAMAWSDGKVVFASGSPFDPVVRPrdGVKVFPAQANNAYVFPALGFAAALTGASQITDDLFLAAAESLASITTDAEIDAGHLFPDMNSIRQVSVTLTAEICEMIVKSGLGRAPSGvsthADWLAYIESHQYDP----------
>UniRef50_B4J7G1(47-589:615) Malic enzyme n=3 Tax=Drosophila RepID=B4J7G1_DROGR   E=1e-180 s/c=1.17 id=29% cov=95%
---------------SGLKMLRIASLNKSSAFSHRERQLYNIHGLLPVAVRSIDRQVEACSKYLATLTTYYQKHIFLTELETHDRKLFYSMLMSNPEKYLSVYHSSSAKDSVIHYSHLFTKCKGMFVTIKDRGHVLQVLSNWPHRHaVRYLIVTNGEVVLNMGDHGVNGYPMVFSKLHQSVVYGRVPPETCLPIMLDCGTNNEHLLQDPLYVGWPHRRITGPEYESFFEEFMLAVMRLFgPRTLIQTKNFNIKDSIKQLELYRKRQCIMDIDLQCLGACGLAGLLVANRISNRKLTDNTILLYGYGAFNVGMAYTCLAQLKHMRLDESAARDRIWFCDDKGLVVHSRcDDTVPVHlLKFVKRHEPIS---------SLCEAIEAIKPNVLVGCSKQPNVFSKEVIKAMEQSCKQPIIYSMTRQSELAECSANDAFVYTKGRCIFISASELPPLKYANKWYQPGYCNVNYMLPGLTLGVMLSGMTSVPDDTFLVAAQRLANLVWPNDLEMRNCFPPIRKLKCINQQITDTVFSYAYRRRIATlWPEPSNPTSYIESMMYQTDY--------
>UniRef50_C1E598(7-507:514) Malic enzyme n=4 Tax=Chlorophyta RepID=C1E598_9CHLO   E=1e-180 s/c=1.27 id=38% cov=88%
-----------------------------------------------------------ALNGFRAASRAIDKYVFLRQLQHEDAGVFYRLLVNNAMEIMPYVYTPTVGEACQTYHTLPIAQQGVYITADDKGRVGEALRSRAppslANDLKVAVVTDGERILGLGDLGAGGMGIAEGKILLYSVCAGIRPNQCLPVCIDVGTDNKSLLEDPMYKGLRRERLRGREYDEVVEEFMSEMRSWQPRCLVQFEDFGNTNAFRILERYRHRQPCFNDDIQGTACIALAGVLSGLRTTGADLTEQRILFYGAGEAGVGIGELIAMALEKRGMSHHDAINRCYFMDSKGLVCKQRLD-APQTPKHALQPHKVAFAHDVPYEPDLLSAIDAIKPTVLIGVSTIHGAFDERVVRKMAAINPRPVIMPLSNPTSKAECTFEQAVTWTEGRVVFASGSPFPAMTYRGKTLHPAQANNAYVFPALGHAAVLAGAREVSDDAFLAAAEALSAMTTEAELAAGKLFPDFDSIREVSHDLTARVCELMERDGQGVKPAGvTDWKKYVDSQFWEPE---------
>UniRef50_A8HPY0(144-719:824) Malic enzyme n=1 Tax=Chlamydomonas reinhardtii RepID=A8HPY0_CHLRE   E=1e-150 s/c=0.93 id=36% cov=88%
--------------------LREPSLNRGLATPAAVRRELGLEGLLPAPVTPPELEVARAAAGVERagAGGPLLAYEALMGLRERDRDTFFALVQGDVERYLPLIYTPTVGDACVSWGSLLLRPTGLTISLADAGRVQQLVDNWAagQPQARIAVITDGERILGLGDLGAHGLGIPVGKAAVYGA-AGVEPSWVVPVVLDVGCDTPEVVTDPLYVGLRRRRERGPAYYQLVDEAVAALRRTYgPGLLVHWEDVGGSHAVPLLQRLQAAgVPTFNDDIQATAAVALAALLGAERVPGVpPLQQQTFLFFGAGQANLGVAALLVSELVSRGVSEEAARGAVWLVDSRGLVTDDRPNLSRSKAVFAKPRPPALGAPGSSGLAslglgasnavgggagggaagggggdSLADLVQGLRPTALIGAAAVGGAFDREVLELLAQVQPsgssRPIVFALSNPTSKAECSFEQAWRYTGGRAVFASGTQFAALTapapsrslfdallpsssshnsttnnnssnnssgspaggfaYGGRTLVPAQANNCLVFPGLGQGCVVSGAVAVTDGMLLAAARAVAAMATPADLEAECVLPRVGRL--------------------------------------------------
>UniRef50_A5C6I9(40-493:498) Malic enzyme n=2 Tax=rosids RepID=A5C6I9_VITVI   E=1e-128 s/c=1.02 id=40% cov=68%
-------------------------------------------------------------------------------------------------------------------------------------------------QVDMIVITDGSRILGLGDLGVQGIGIPIGKLDMYVAAAGINPQRILPIMLDVGTNNQRLLEDRLYLGLRQPRLEGEEYLSVVDELMEAIFTRWPKAIVqvhffksttivifylmhvilltgwmgksyQFEDFQMKWAFETLQRYRKKFCMFNDDIQGTAGVALAGLLGTVRAQGRPLTDfvnQKXVVVGAGSAGIGVLNMAAQAASRiAGNTGASPNHQFYLLDKDGLITKERKNIDPAAAPFAKGPGEI---EGLREGASLLEVVKKVKPHVLLGLSGVGGVFNEEVLKAMRESdSTKPAIFAMSNPTMNAECTAADAFKHAGENIVFASGSPFANVNL--------------------------GAHFISDGMLQAAAewvyiedhtlslidfvkwlfvrygESLASYMSDEETQNGILYPSIDSIRHITAEVGAAVLRAAVAEELAeghgdvgprelEHMSKEETVEYIIRNMWFPIYSP------
>UniRef50_UPI0001B4344E(5-319:321) malate dehydrogenase n=1 Tax=Listeria monocytogenes FSL J1-208 RepID=UPI0001B4344E  E=1e-120 s/c=1.38 id=43% cov=55%
---------------SGFDYMNNPLLNKGTAFSKEERASYQLDGLLPPIIETIEQQAVRIESQIENLETPLHKHQLLTNLYNENRTLYYYVVTKNVTDYLPIIYTPTIGDAVIHYHADYNAPdEALFIDAFAPEKLSASIKNYAknNPNIDMIVITDGEGVLGIGDWGVNGVKIAVGKLAVYTVAAGLAPDRVLPVVIDAGTNNETLLNNPMYLGNKRPRLAESEYDAFIASFVEVMKEVFPKAILHWEDFGRANASRILHNYRDKICTFNDDIQGTGAMVVAAVLATIQVSQIPLSEQKIIIFGAGTAGIGIADQLSAQLMREtGLPFE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P16468(113-471:478) NAD-dependent malic enzyme n=137 Tax=cellular organisms RepID=MAOX_BACST  E=1e-45 s/c=0.52 id=29% cov=58%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDGTAVLGLGDIGPYaAMPVMEGKAMLFKEFAGVD---AFPICLDT-KDTEEIIQ-----------------------IVKAIAPAFGG--INLEDISAPRCFEIEKRLKEEldIPVFHDDQHGTAVVLLAGLLNALKIVDKKLEDIKVVLTGIGAAGIACTKILLAAGVR----------NIIGVDRHGAIHRDETYENPYWQEYAQ------LTNPDNLKGSLSDVIAGA--DVFIGVSA-PGILKVEDVKKMARD---PIVFAMANPIP--EIDPELA-------------EPYVRVMATGRSDYPNQINNVLCFPGIFRGALDCRAREINEEMKLAAAKAIASVVTEDELNETYIIPSVFNSKVVER-VRQAVVEAAYRTGVARKDNIP-----------------------
>UniRef50_Q8PTT0(72-407:439) NAD-dependent malic enzyme n=2 Tax=cellular organisms RepID=Q8PTT0_METMA  E=7e-39 s/c=0.49 id=34% cov=53%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVTDGSAVLGLGNIGPYaALPIMEGKAIIFKEFAGID---AFPICL--GT------QD-------------------TEEVIKAVKNMAP-AFggINLEDISAPRCFEIEARLREelEIPVLHDDQHGTAIVVFAGLLNALKIVKKDLAELKIVISGLGAAGVAI----LKFLVRAGANP----AKILACDSQGIVYEGRE------KGMNTIKDEISRITNPERLKGEL---KEVFPGAdlFIGVS-VGGIVTGSMVRSMAKDA---IVMAMANPVP--EIMPEAAKRA--GARIVATGrSDF-----------PNQLNNCLSFPGIFKGALGTCARKITPEMEMAAAHALANVVTSGELSEDHIIPD------------------------------------------------------
>UniRef50_A2BJ64(52-386:465) Malic enzyme n=27 Tax=cellular organisms RepID=A2BJ64_HYPBU   E=5e-37 s/c=0.47 id=33% cov=53%
------------------------------------------------------------------------------------------------------------------------------------------------------VVSDGTRVLGLGAIGPEG-ALPVmeGKALLFKALGGVD---AVPLV---------------------HRARDRE--KFL-ELLVLIEPSFGG--INLEDIESPKCFYLLDEARKRlnIPIWHDDQQGTATVTLAGLINAAKLTGRDLRKMRIALIGAGAANT----ALYRLLKAYGVDP----KNMVVVDSKGVLHSQREDIEKLKEKNPWKYQiavetdggwnQLRGGGIKEALEGAEAVVAASKPG--------PGVIKPEWIKLMDKD---PIVFAEANPVP--EIWPWEAKEA--GARVVATGrSDF-----------PNQVNNSLAFPSIFRGVLDVRARTITDTMAIAAAEELARFAEEKGLREDYIIPSMEE---------------------------------------------------
>UniRef50_B2S8E0(80-390:466) NADP-dependent malic enzyme n=20 Tax=Brucella RepID=B2S8E0_BRUA1   E=1e-35 s/c=0.50 id=32% cov=51%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVISNGTAILGLGNLGAlASKPVMEGKAVLFKRFADVD-------SIDLEIDTTD-----------------------IDAFINAVRYLGPSfGGINLEDIKAPDCFIIESRLRElmDIPVFHDDQHGTAIIAAAGLINALHLTGRDMKTTKLVCNGAGSA--GIA--CIELIKAMGF----APENVILCDTKGVVYQGREEGMN-QWKSAHA--------VKTDRRSLADAMKDA--DVFFGVSAK-GALTQDMVRSMA---PNPIIFAMANPDP--EITPEEVERIRD-DAIVATG----------RSDYPNQVNNVLGFPYIFRGALDVRATTINDAMKIAAVNALAELARED----------------------------------------------------------------
>UniRef50_A0LVF9(131-496:504) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=1 Tax=Acidothermus cellulolyticus 11B RepID=A0LVF9_ACIC1  E=1e-35 s/c=0.42 id=30% cov=55%
----------------------------------------------------------------------------------------------------------------------------------------------------VAIVTDGTAVLGLGNIGpLAALPVMEGKSLIFKEFGGVNAY---PICLNAPT--------P---------------DAVVEATI-AIAPGFGG--INLEDIAAPACFGIEARLQAEldIPVFHDDQHGTAIVVLAALLNACRITGRTFPDIRVVLVGCGAAGTAISLALLEAGVRDLV----------IADRDG-VLHDGNAALPHHRELAARSNPRGIRDVRTAMHDA---------DVFIGT-ARRGSIDPEWVKLMS---PHPIVFALSNPEP--EILPHEV----GPDALLATG----------RTDLPNQINNALCFPGFFRGALDARATRVTSAMKLAATRAIADTVTDEQRAIGVIVPTMFQA-ALHQAVAKAVA--------------------------------------
>UniRef50_A7HKA3(14-359:376) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=1 Tax=Fervidobacterium nodosum Rt17-B1 RepID=A7HKA3_FERNB  E=1e-35 s/c=0.44 id=33% cov=55%
------------------------------------------------------------------------------------------------EENLKLLYTPGVADVaklCAE------NPEKTFIYTRRKHTI--------------AVLSDGSTVLGLGNIGPYG-ALPVmeGKAVLFKQFGDLD---AFPICIDT-QDVEQIIN-----------------------IVKVLEPSFGG--INLEDISAPRCFEVLERLNNEmnIPVFHDDQQGTAVVVIAGLLNALKLAEKKIDEVKIVVNGIGAAGYNIVKLLI----------EIGAKHIVPCDINGII-NRKTALHKYHLEVSELTGNL------NNSGNLKDAI--IDADVFIGVS-KGGILKGSDIRKMSK---KPIIFALANPVP--EIFPDEAYE--DGAFIVATGrSDF-----------PNQVNNLLAFPGI-MKVAVEKQVKITKEMLIRAAEILSN---------------------------------------------------------------------
>UniRef50_A4X4W4(139-467:513) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=179 Tax=root RepID=A4X4W4_SALTO  E=1e-34 s/c=0.46 id=32% cov=53%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDGSAVLGLGNLGpAASLPVMEGKAALFKRFGGVDAW---PVVLD-----------------------TQDTDEIV-AIVKAIAPAYGG--INLEDIAAPRCFEIEAQLRAalDIPVFHDDQHGTAICVLAALTNALRVVGKELAQVRVVVSGAGAAGTAIMKLLL----RQGVGD------IIAYDRRGALHRGMTGLNPAWQWLAE------HTNRENYSGDLAGAVRDA--DVFIGVSA-PNLLTGDDIAAMAKDA---IVFALANPDP--EVDPREARKHA---AVVATG----------RSDQPNQINNVLAFPGVFRGMLDAHAEEFTEEMAIAAARAIADVVGEEKINPTVIVPSV-----------------------------------------------------
>UniRef50_P27443(72-614:643) NAD-dependent malic enzyme, mitochondrial (Fragment) n=20 Tax=cellular organisms RepID=MAOM_ASCSU  E=0 s/c=1.37 id=41% cov=96%
----TPKKRS-------AELLKEPRLNKGMGFSLYERQYLGLHGLLPPAFMTQEQQAYRVITKLREQPNDLARYIQLDGLQDRNEKLFYRVVCDHVKELMPIVYTPTVGLACQNFGYIYRKPKGLYITINDNsvSKIYQILSNWHEEDVRAIVVTDGERILGLGDLGAYGIGIPVGKLALYVALGGVQPKWCLPVLLDVGTNNMDLLNDPFYIGLRHKRVRGKDYDTLLDNFMKACTKKYGqKTLIQFEDFANPNAFRLLDKYQDKYTMFNDDIQGTASVIVAGLLTCTRVTKKLVSQEKYLFFGAGAASTGIAEMIVHQMQNEGISKEEACNRIYLMDIDGLVTKNRKEMNPRHVQFAKDMPE---------TTSILEVIRAARPGALIGASTVRGAFNEEVIRAMAEINERPIIFALSNPTSKAECTAEEAYTFTNGAALYASGSPFPNFELNGHTYKPGQGNNAYIFPGVALGTILFQIRHVDNDLFLLAAKKVASCVTEDSLKVGRVYPQLKEIREISIQIAVEMAKYCYKNGTAnLYPQPEDLEKYVRAQVYNTEYEE------
>UniRef50_A2QY66(49-605:609) Malic enzyme n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2QY66_ASPNC  E=0 s/c=1.31 id=41% cov=97%
---------PLVCPFEGRDALQSCQFNKGSAFTEEERKTFKLHGLLPPNIQTLEEQVQRAYEQYSSRDNDLAKNTFMASMKAQNEVLYYKLIDTHLKEMLSIIYTPTEGDAIQNYSRLFRKPEGCFLNIRDQDRIEECLSNFSRgEEVDYIVVSDGEEILGIGDQGVGAILISVAKLALTTLCAGIHPSRQLPVVLDCGTDNESLLTDELYLGLRQSRVRGEEYDQFVEKFVETARKRFPRAYIHFEDFGLHNAKRILDKFKSRIPCFNDDIQGTGCVTLAALLSGFHVGGIELEDARVVVFGSGSAGTGIAEQLADTIATEThKPKEEASKQIWCLDKPGLLVKSLGDqLTPAQVPFARDDKEW----PDADSRDLLSVVKKVKPHALIGTSTKPNSFTEDVIREMAKHVEKPIIFPLSNPTRLHEAQPEDINRWTDGRALIATGSPFPPVDRNGGKYEIAECNNSTCFPGIGLGAVLSRTRTLSNKMLVSAVKALAARSPALQDPNGPLLPDVRDVRELSVDIAKAIIKTAVKEGHAeeegIPTNEDELEEWIRAQMWEPVYRPLVK---
>UniRef50_P37225(25-597:601) NAD-dependent malic enzyme 59 kDa isoform, mitochondrial n=14 Tax=Eukaryota RepID=MAON_SOLTU  E=0 s/c=1.27 id=40% cov=95%
----------------GADILHDPWFNKDTGFPMTERDRLGLRGLLPPRVISFEQQYDRFMESFRSLEKNtegqpdsvvsLAKWRILNRLHDRNETLYYRVLIDNIKDFAPIIYTPTVGLVCQNYSGLFRRPRGMYFSAKDKGEMMSMIFNWPSTQVDMIVLTDGSRILGLGDLGVQGIGIPIGKLDMYVAAAGINPQRVLPVMLDVGTNNQKLLEDPLYLGLRQPRLEGEEYLSIVDEFVEAVHARWPKAVVQFEDFQAKWAFETLDRYRKKFCMFNDDIQGTAGVALAGLLGTVRAQGRPLTDfanQKIVVVGAGSAGLGVLKMALQAVSR--MTGPSADPHFFLLDKNGLITKDRKDIDPAALPFAKAHHEIEGLGLQEG-AGLAEVVKKVKPHVLLGLSGVGGIFHEEVLRAMKEsDSVRPAIFAMSNPTNNAECCPVDAFKLAGEDIVFASGSPFANVDLgNGKIGHVNQANNMYLFPGIGLGALLSGARNISDTMLEAAAECLASYMSDDEINRGILYPSIDDIRDITAEVGAAVLRAAVAEDLAeghgdvgvkelQHMSKEETIEHVRQNMWYPVY--------
>UniRef50_C1F344(9-563:564) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F344_ACIC5  E=0 s/c=1.29 id=47% cov=98%
--PRTRK-----VNVAGFNLINSPRLNKGTAFTNRERDLFSLHGLLPPHVGTLEEQVDRRMRAFDDQRTAFHQYAFLRDLQDLNETLFYALLVRNIEKLLPIVYTPTVGEGCMRFSEIWRKPRGVFLSYPNKDRMRQILSHPRYDKVRCIVVSDGERILGLGDQGAGGMGIPIGKMALYTALGGIPPEQCLPVLLDVGTDNEERLANPIYMGWRHARIRGLEYDDFVDAFVQCVKERWPHVLLQWEDFAGANASRLLARYRHQLCTFNDDIQGTAAIAAATLISAIHITGVPLTEQRIVLFGFGSAGLGIANLLVRLMQQKGCTPEKAQERIHAIDVDGLLVEGRANIKDEQKMYARTAESVKGWKQENGAIRIEEVIRQVRPTALIGVSGQAGAFTEEVVRTMAQHVERPIIFPLSNPTSRSEAHPHDLLTWTDGRALVGTGSPFEPMTLRGKTLQVAQTNNSYIFPGLALGIISAKARHVTEDMILAATTELILHLPTCSDSNACLLPPISEARTIARHIGEAVGRQALREGQAQVADEAELLRALDENHWEPAYEEYER---
>UniRef50_B7FZD7(5-543:555) Malic enzyme n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FZD7_PHATR  E=0 s/c=1.30 id=42% cov=95%
------------LPVTGVEVVRDTIRYSGVSTPISEREGLGIRGLVPAAFLPLELDVERCMLQMRSKESPLEKYIYLHNIQDVSERLFYAILCKYTSEVMPLVYTPTVGEACQNFSAIYRGTlRGMYFSLEDSGKIRTLLDNWFTSKITTIVVTDGERILGLGDLGVNGMGIPIGKLALYTACGGIDPAKVLPVHIDVGTNNEENLNDPYYLGLRRPRERGQAYDDLIAEFFEAAQNKFGaNVMIQFEDFGNLNAFRLLSAWQDKACTFNDDIQGTAAVALAGLLASNRLTGKDLIDHIFLFAGAGEAGTGIAELLALAIAEKGhLPIEQARKKIFLVDSKGLVTKSRLDsLQHHKVDFAHDVD---------DCPNLLAAIDMLKPTGLIGVSAIPNSFTKEICENMAAHNKIPVIFALSNPTSKAECTAQEAYEWTDGRAIFCSGSPFDPVTLQdGRQRVPGQGNNAYIFPGIGLGVLAAGSTRITNYDMLLAAETLAAEVGPEELDVGCMYPPLSRIRQVSKNIAIAVANQAHETGVATEQRPVDMGKYVESLMYDP----------
>UniRef50_B4MPG5(261-782:801) Malic enzyme n=1 Tax=Drosophila willistoni RepID=B4MPG5_DROWI   E=0 s/c=1.32 id=36% cov=92%
----------------------------GLAFTMEERQILGVHGLWPCSYRTIHDQLYAVMANFNARSDNIGRFTYLLSLSRRHQRLFFRFLREHLEKVMPIVYTPTVADVVNAYGLLFRDPTGLYVTIFDRGHIIDVLKNWrAEKQVRAVCVSDGGRVLGLGDMGASSMGICVGKMALYTALGGVPPNQLLPIALDVGTDNEELLNDPLYVGARTKRVQGDEYEEFVQEFVDAVLECFgPNTCIHFEDFATPNAFKFLEKYQRSFCCFNDDIQGTGAMSLAGFFNVERVVQRKLEDHVFLFAGIGSACLGIANMLLSELKRRGLKQKDACQNIYMINEHGLLNDALPGCVNEARKFAK----------PLDCVKLDEAVEQLKPSILVGGSSVRGLFTEEVLRLMAKYNERPVIFALSNPTNKAECTAEQAYQYTEGRAIFCGGSPFPPVTYNGKRLQPGQANNCLIYPGLALGAISARASYLPNEVFSVAASTIAKFTSEENLNSGNMYPSMRDANEVSFHVGVSVAEYLIENDISnLRPLPENICEYMKNRQYSLDY--------
>UniRef50_A9G3I5(50-606:607) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=12 Tax=Bacteria RepID=A9G3I5_SORC5  E=0 s/c=1.23 id=44% cov=97%
--------------FDGIALLRLVMTNKGTAFTPEERVNLGLDGLLPPQVNTMDQQLARVYGGFRREPTPIAKYQYLRALQERNEILYYALLNRHLGEMLPIVYTPTVGEAVQQFNFLYQSARGVSFSPVNIDRAERVLASFPWEDVRMIVATDSSAILGIGDQGYGGLAIPIGKLALYTAGGGVSPFHTMPVVLDVGTDRADLIEDPFYLGVRQRRLRGDAYFDFFDRFVDAVKSSCPRAVIQWEDLSKEAAFSVLDRYRKVIPSFNDDIQGTGAVTLAGVVAACRLRGERLRDQAVVIHGAGAGGVGVAWAICQGMLREGLTEDEALARIFVLDSKGLLAKDRP-MEEYKRKFAQDPAKIAAWKKAGAVPTLLETLENTRATVLLGLSGQPRSFSEPVIKAMAANTPRPVIFALSNPTSACEALPEEILALTEGRALVATGSPFPPVELDGKTLPIGQGNNAFIFPGLGFGSILSDAREITDGMVLAAAYALVDYTAEKHLDKGLIYPPVEELQEVSTRVAIAVIRAAFEDGVARskKVDSGNVEAYVKARFWQPKYLPFVR---
>UniRef50_A1SVL3(20-570:571) Malic enzyme aka malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=4 Tax=Gammaproteobacteria RepID=A1SVL3_PSYIN  E=0 s/c=1.22 id=41% cov=98%
------------VSLTGNELLNNRTLNKSTAFTYQEREDFDLNGLLPPRVQTFEDQLKRVYQGFSASSTDIEKYQYLRALQDRNETLFYALISRNIEEMTPIIYTPTVGKACQEFSHRFQIARGLYLTTDNIHDVGSMAREFTGKDIQIIVVTDSQGILGIGDQGVGGMGIPIGKLSLYTLGAGIHPDHCMPIALDIGTDNQDLLADPMYLGIPKKRLTGEPYKAFIKTFVEQVKLHFPKAVLQWEDFSKSNAFDNLSDYEDELPSFNDDVQGTGAVVLAGIIGSTKMKGETLIDQTYAVYGAGAGGVGVADQIFAGLLKEGLSHQEARDRIFILDSRGVVFADREGLDEYKKRFAKPVELAKDWQlADSNKVNLTELLDNVPVTVLLGCSGVGGAFKEHHIKKMLDHTARPMIFPLSNPTSCCEAVPEDIYKWSDGQAIVATGSPFADLHFKDNIYRIGQGNNIFIFPGVGLAAITAEVKKITKDMFTTASFALADYVSQEDLDAGCVFPKISELRDVSLHVAKAILEQIQQTDPECHLRDKDITKELALRMWEPAYLPYRR---
>UniRef50_A4IYN9(21-601:604) NAD-dependent malic enzyme n=17 Tax=Francisella RepID=A4IYN9_FRATW   E=0 s/c=1.13 id=44% cov=97%
--------------LTGRQLLNNRVLNKDVAFSQEERVAFDLIGYLPEKVESLEEQAIRVRRQLDLKPNSLEKYVFLNRLHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHKKHIARILERYEYNSIDLVLVTDGEAVLGIGDQGIGGMNISIGKIMVYVAASGIDPARVLPVQLDMGTNNDALLNAPGYLGVRLPRVSGETYDEFIEEFVTQVKARFPNVFLHWEDLGRDNATRILEKYKDKLCTFNDDIEGTGIVATANCIAGVKTASTirinageitveealsGICDIKVVIFGAGSAGCGIARQLADVIAdRAGVSIEKARSSIYLVDRYGLVCDRLraKRITPEQKLFVKTSEEIDKWKvEDFNYITLEETVKNTKCDILIGTSGQPGSFTKEIIKTMAKNNNYPIIMPLSNPTSLCEALPEDIIKWTNGKALIAAGSPFPDVTYNGRDYRISQGNNAFIFPGLGLGSVAVHARVLTKGMIRAACYRLSELSPMviNEDITQPLLARITDLVDVTKEITKAVAKQAILEGVHGVdidledltetELDEEIERLINLSSWTPTYAPY-----
>UniRef50_A0AK20(6-545:547) MalS protein n=16 Tax=Listeria RepID=A0AK20_LISW6   E=0 s/c=1.21 id=40% cov=95%
----------------GFDIMNNPLLNKGTAFTKEERSNYNLDGLLPPIIETMEQQAIRIENQIKNLETALHKHQLLTNLYNENRTLYYYVVSKNVTEYLPLIYTPTIGDAVINYHKEYSAPdEALFIDAFAPEKLKTSIENYAknNPAIDMIVITDGEGVLGIGDWGVNGVKIAVGKLAVYTVAAGLAPDRVLPVVIDAGTNNKSLLDDPLYLGNKRPRLSEKEYDLFIASFVAIMNEVFPKAILHWEDFGRANASRILQHYRDKICTFNDDIQGTGAMVVAAALATIHVSHIPLNKQKIIIFGAGTAGIGIADQLSAQLMREtGLPFDTAKKHFYLVDRNGLILDNMTDLTTGQKKYAQQASEWASM----PAGTLEELVEAIHPTMLIGCSGVTGAFKESIVRKMSDHTERPAILPLSNPTKLAEATAADLINWTDGKALIVTGSPSEPVEYQNTTYEIGQANNALLYPGLGLGALVTRAKFITDGMLAAASKAVADQISPSEPG-AALLPHVRTLRETSQAVAIAVANEAVKENIHQI-ELTNIREAVEREMWHPTYK-------
>UniRef50_Q7K3R0(69-606:633) Malic enzyme n=9 Tax=Sophophora RepID=Q7K3R0_DROME   E=0 s/c=1.19 id=31% cov=95%
---------------DGLWMLNQSNYNKGLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTNNVQQYIYLTYLSRRNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICIKDLGHVSQILSNWPFRCVRCLLVSNGASVLSVGDLGVDEMPILFSNLHQNVVYGGIHPAYCLAVMLDVGTNNEELLNDPMYTGLRERRCSEKLYDQLFEEFTLSVMQQYgPRALILCKDFEAQKAKKQLELYRERQCIVDVDFQCFAAVALAGVIVCNRLKRVFFSSNVFLFYGAEAINIGMARLCMVLLKREGLIEMKAREKIWFFDANGLVVLGRKDIPEELLEFANQRDPILD---------LVEAIQELKPNILVGGSSLPNTFTPDVLRAMEKSADQPVIFALSRPLEQTECSAEDAFSYTKGHCIFISGSKLPPLKYANKWYQPGHCTSSYLVAGISCGVMLAGFTNIPDEAFCVAAERLASLVWPCDLEKRNVYPPMRKIQCISLQIAEAIFSYAFGRGLATlYPQPENPMEYIKNSMYNPEYR-------
>UniRef50_A8HYN3(69-617:617) Malic enzyme n=1 Tax=Chlamydomonas reinhardtii RepID=A8HYN3_CHLRE   E=1e-178 s/c=1.14 id=38% cov=95%
---------------SGVDLMRHPKYNKGLAFSDAERDRLYLRGLLPPAVLSQEVQLERTLLNIRSKDSDLEKSTYMQSLQERNERLFHRVLVENMEELLPVVYTPTVRLACQKYGLMFKSlPRGLFITLEDRGRVFRILKNWPERNVKLLVVSDGERVGDLGDLGVQAVGVPISKISLYTACGGISPSITMPVMVDVGTDNEELLRSPFYVGVRHKRVRGDPYYELMDEFLTAVKRRFGNtVLVQFEDMAYDNASKLLNMYRTEFPCFNDDMSGTAAAVLAGVLAALPRTGGRLADHRIVFVGEGAVVACIAELFATAVATAtNQTVLDARKRMWLVDSQGLVTRERGDsstLESFKLPFCHS--------VGSECRDLASAVQLLQPTVLVGLSTtgpaPPWAFSQDVLQAMAASCRHPLIFPLSAASP--ECSAEDAYRATDGRALVATEQRVAPVTLPsGRTLHPSQCTSTYIFPGVGLGSLIARCTKLRDEQFIAAADAVSRLVGEEDLARGSLYPPLSRIRDVSAAVAKAVAQKAYEGGFATAlPKPHNLYEAARQSMYHPQYRRYR----
>UniRef50_Q95061(1-557:557) Malic enzyme n=3 Tax=Giardia intestinalis RepID=Q95061_GIALA   E=1e-161 s/c=1.02 id=37% cov=96%
------------MPITISTVLRNKDCNKDTAFTAAEREAHHIVARLPARVETIEQQISRCRAQFDVLTTPTEKWLYLTRLQEVNETLFSGFCLKYLKEVLPIVYTPTVGTACSNYSLLWQgYPRGFYLNRTHLGKVKQIFDQWPY-SPRIIVATDGTRILGLGDLGTGGHQICVGKLTLYSLGGGFAPEHTLPISFDFGCNTDKIREDPHYLGIPEKRNKDDTYYGIIKETIEAVHSKWPDCIFQFEDFSNDTAFTLLKKHRDAGPVFNDDIQGTGCIAAATIAAGLRAISLKMnrtakaSEQVYVMFGAGAGGIGVADNIASLSVSEGYTLEQARKQFYVIDSQGLLTADRDDFVNGTMP-GHKLPYVRHDLSIKGHTTLLSVIKAVKPTCLLGLSTVGKSFTREILETMCEGLPTgqpPIVLALSNPTEKCECTFAECMEYTNNTAYYASGSLMPSLTLpNGTTIQPAQCNNFYVFPGIGLGAYVCRAKKITDEMITGVSGALAQMVPEEKLRRGELLPDLDEIREISCQCALGLIRIAEKQGQSRRILPSsdtELLAQLRDTQWSPKY--------
>UniRef50_A4SKB8(7-512:516) NAD-dependent malic enzyme n=3 Tax=Aeromonas RepID=A4SKB8_AERS4   E=1e-154 s/c=1.08 id=45% cov=90%
----------------------------GTSLPYAERKRQGLMGRMPHKEESLAQQRRRIYRLVSAMQSPFDQHLLLRQLQEDNPVLFYDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDRDDLDAIFA-AVEQEVDVIVISDGERVLGLGDLGIGGMGICIGKLALYSAAGGINPARTLPLCVDVGTNNPELLEDDSYLGWQANRVDGESYYHFMDKVVAAIRTRWPQVVLQFEDFAGKHAANLLARYRDELCMFNDDIQGTAAVASACVLAGLQQAGTTLADTPVLIVGAGSAGCGIAAMLARL--------AGSPERVQLFDQDGLVCLDRANLTPSQRPFARPAQEA--------CAELPALIERLRPGVLIGVSGQGGLFTEAVLGAMGEVCERPVILPLSNPTRSAEATPEQVWQATAGRALLATGSPFAPVTVAGEARVVSQCNNVYVFPGIGLGACAVKARRISDGMLQAAVRAVGAYP----LAEGRLLPPIEQVGEVARAVARAVALTARDEGLADFGGDPAPL--IDQTWWRPHY--------
>UniRef50_A3YYQ0(2-515:517) Malate oxidoreductase n=1 Tax=Synechococcus sp. WH 5701 RepID=A3YYQ0_9SYNE  E=1e-152 s/c=1.05 id=42% cov=91%
--------------------------------------------------ESLETQVERHWQAFLSLRNDLERFRFAVALRQANLTLFHRFLADHIEAVMPIVYTPTVGAAIQRFSLDYRTPSgGVFLAAPDLERIESVLSQAATGPVDLILITDSQGILGIGDQGIGGIEICLGKLAVYTLCAGLDPARVLPLVLDVGTDRVELLENPLYPGWRHPRLDGLDYDRFLARSVEALQRQFPGALLHWEDFGTGHAHQLLERYRLQLPSFNDDIQGTRGVACAVVKAASHGAGLPLEDHRIVVFGAGTAGCGIAEGLVRLLTRAGLSEPEARRRIWAIDREGLVLADQPGLSPMALALARDPSERSLFEHDTqGRIGLLEVVRAIQPTVLIGTSTVTGAFSREVVDTMAAAVERPIILPLSNPTRLAEATPADLYAWTGGRALVASGSPFEPVSWQGSLRRIGQCNNCFLFPGLGFASVAVGATQVSEGMIDAGLDALADRIPAFRDPEAPLMPELTQVQAVSRAVAEAVALAAVHEGLASRAASAEEAiERLDQATWTAAYRELE----
>UniRef50_Q4T5P0(5-289:306) Malic enzyme (Fragment) n=1 Tax=Tetraodon nigroviridis RepID=Q4T5P0_TETNG  E=4e-93 s/c=1.21 id=37% cov=50%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DCLIQFEDFANINAFRLLSKYRDMYCTFNDDIQGTAAVAVAGLLAALRITETKMSDHTIVFQGAGEAAMGIAELITMAMKKEGLPEQECLKKIWMVDSKGLIVKGREHLTHEKERFAHEHQQMKK---------LEDVVKELKPTAII--------------------VTQP---------AKAECTAEQCYTLTEGRGIFASGSPFDAVTLPdGRTLHPGQGNNAYIFPGVGLGVTACSIRHITEDIFLTAAEALANLVTEKDLNEGRLYPPLSSIAGVSLKLAVKIMEYAYKHNLATlRPEPSDKEAYVRALIYSTEYDEF-----
>UniRef50_Q2LPM4(110-467:479) NAD-dependent malic enzyme n=114 Tax=cellular organisms RepID=Q2LPM4_SYNAS  E=7e-85 s/c=0.89 id=32% cov=57%
----------------------------------------------------------------------------------------------------------------------------------------------------VAIVTDGSAVLGLGDIGPEaALPVMEGKAVLFKSFGGVD---AFPICLN--TKNPE-------------------------EIIQAVKWIAPGfGGINLEDISAPRCFEIEQRLKKEldIPVFHDDQHGTAVVILAGLINALKIVGKRIEEITVVVNGLGAAGIASISLLSAAGVR----------KIIGCDRGGILYRGRqEDMNPFKAELA------LTTNPEGLKGGLADALRGA--DVFIGLS-RPGLLQGKDISKMARD---PIVFAMANPVP--EILPEEA-------------EPYAAVVATGRSDYNNQVNNVLCFPGLFRGALDCHARDINQEMLLAAVHAIATAVKADALRRDFIIPSIFD-PTVQPRVAAAVMEAARKTGAA-----------------------------
>UniRef50_D1C9C4(494-837:841) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=14 Tax=cellular organisms RepID=D1C9C4_SPHTD  E=4e-82 s/c=0.90 id=28% cov=60%
----------------------------------------------------------------------------------------------------------------------------------------------------VAIVTDGSAVLGLGDIGPQaALPVMEGKAVLFQSLAGVE---AFPICV--------AERDP----------------QAIVDIVTAIAPSFGG--INLEDISAPRCFEIEAALKERldLPVFHDDQHGTAIIVLAALLNACTLRGTPLEEVKIVINGAGSAGVAVARLLLTVGVGD----------IILCDRRGIVHRGRQDLNRVKEELAR------LTNKEQITGTLTEAL--VGADVFIGVS-VAGALTQEMIRSMA---PDPIIFALANPEP--EILPDEAKEA--GAFVVATG----------RSDYPNQVNNSLAFPGVFRGALDARATDINDAMKLAAARAIADLVSPKELSRDFVIPGALDLHVPAAVAAAV-ARAAVETGVARIPvDPEEVAARTQELIYE-----------
>UniRef50_D1C9C4(34-420:841) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=14 Tax=cellular organisms RepID=D1C9C4_SPHTD  E=1e-65 s/c=0.65 id=29% cov=67%
--------------------------------------------------------------------------------------------------VLSLVYTPGVAEACRVISEDPLSS----FELTSRGN-------------TVAIVTDGSDLFGLAAgLPEAALPLLEAKSVLFKTFAGID---AFPICLD--------QRDPL----------------SVVETILALTPTFGAICLDH--ISAPHSFTIADHLEKgsNIPVFSNQHHGSAILVLGALMNALKVVGKQLNEIRVVIGGAGVAGIGIARLLHRVGVRD----------LVVCDRAGAIYPYRPYRMNWAKAYVAK-----ESNPEHRRGSLAEMLRGA--DVFIGVST-GDAVTPEMIAEMARD---PIVFAMALPTP--EISPQEAKAAG------------AAVVGTGRSDHPNMMDISLVFPGVFRGLLDSGARNIRLRTLVYAAEALAGLVPDDELHADNIVPRIFDFR-VAPTLAAAVVRAAKETGEAVHDvEPEEVAEntlrYVYEGMPTARTRP------
>UniRef50_Q5Y0M3(52-444:444) Malate oxidoreductase n=4 Tax=Archaea RepID=Q5Y0M3_9ARCH   E=7e-82 s/c=0.78 id=29% cov=62%
----------------------------------------------------------------------------------------------------------------------------------------------------VAIVTDGTRVLGLGDVGAEaALPVMEGKAMLFKYLGGVD---AFPLCLDT-SDAEDIIN-----------------------TVKWVAPTFGG--VNLEDIESPKCYYILERLQEELgmPVWHDDQQGTALVILAGAINALKVVGKRLSEIAISLVGAGAANMNVAKYLCLAGAKEG--------NIVMVDSKGILNRER---MEDVKRDENKRDMCEKTNKEGRKGGIKEAMRDT--DLCIALSTPgPGVIKKEWVADMANDA---IVFACANPVP--EIWPVEAEE--GGARIVATG----------RSDFNNQVNNSLGFPAVFRGALDVRAARITDGMCIAAANAIARYTeeegkgKEKGISESRIIPRMEE-SEMYVCEAVAVGMKAIEQGVAEKgMSMKALEERVREKISDKTTKPF-----
>UniRef50_B9DS04(34-384:385) NAD-dependent malic enzyme n=5 Tax=cellular organisms RepID=B9DS04_STRU0  E=1e-78 s/c=0.84 id=29% cov=53%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDGSAVLGLGNIGAtAAMPVMEGKAALFKAFAGVD---AIPIVLD--TNDTEE----------------------IIRIVKAISPTFGG--INLEDISAPRCFEIEQRLIEEcdIPVFHDDQHGTAIVVLAAIFNALKLIEKTIEEVKVVVNGGGSAGLSITRKLLAAGAKD----------ITVVDKFGII-----NEKESHKLQPHHQDIAKLTNRDFKSGNLEEALDGA--DIFIGVSA-PGALKAEWISKMA---EKPVIFAMANPVP--EIYPDQALEA--GAYIVGTG----------RSDFPNQINNVLAFPGIFRGALDARAKKITVDMQIAAAKGIASLIPEDELSTTNIIPD------------------------------------------------------
>UniRef50_Q8PTT0(72-410:439) NAD-dependent malic enzyme n=2 Tax=cellular organisms RepID=Q8PTT0_METMA  E=4e-77 s/c=0.86 id=32% cov=53%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVTDGSAVLGLGNIGPyAALPIMEGKAIIFKEFAGID---AFPICL--GTQDTE-------------------------EVIKAVKNMAPAfGGINLEDISAPRCFEIEARLREelEIPVLHDDQHGTAIVVFAGLLNALKIVKKDLAELKIVISGLGAAGVAILKFLVRAGAN--------PAKILACDSQGIVYEGREKGMNTIK-----DEISRITNPERLKGELKEVFPGA--DLFIGVS-VGGIVTGSMVRSMAKDA---IVMAMANPVP--EIMPEAAKRA--GARIVATG----------RSDFPNQLNNCLSFPGIFKGALGTCARKITPEMEMAAAHALANVVTSGELSEDHIIPD------------------------------------------------------
>UniRef50_Q3JAT5(33-423:783) Malate dehydrogenase (Oxaloacetate decarboxylating) (NADP+) n=2 Tax=Nitrosococcus oceani RepID=Q3JAT5_NITOC  E=5e-76 s/c=0.73 id=28% cov=65%
-------------------------------------------------------------------------------------------------------YSPGVAEPCR---EIHRSPDDVYL-YTGKGNL-------------VAVVTNGTAVLGLGPLGPlASKPVMEGKGVLFKRFADID-------VFDIELNAPTA-----------------------EEVIQACQLLEPTfGGINLEDIAAPDCFHIEERLREtlTIPVFHDDQHGTAIISGAALLNACELAGKRLEDIKLVMNGAGAASIACAK----FYLTLGVDPD----NLLLCDSKGVLYKGREDLMPGRPRY---NEYKAQFIRPTRLRTLPEAL--AGADAFCGLS-VANVVTPDMVRSM---NDNPIIFALANPDP--EITYPDAL-AARPDVIMATG----------RSDYPNQVNNVLGFPFIFRGALDVRARAINEAMKVAaaqalaalakegVPESVCRAYGMERIEFGreYLIPKPFD-PQVLLEVTTAVAKAAGESGVARVP-IRDFRAYREQ---------------
>UniRef50_D2RJ33(36-409:416) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=6 Tax=Veillonellaceae RepID=D2RJ33_ACIFE  E=8e-76 s/c=0.77 id=31% cov=60%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVISDGTRVLGLGDIGPEaAMPVMEGKAVLYKKFGDVD---SVPICIDT--------KDP-------------------EEFVNIVEKLQPSfGGINLEDISSPKCYAIEAELikRCKIPVFHDDQHGTAIIACAAIMGALRYVKKDIGKVKVVVNGCGAAGSAIGKLLVRLGVKD----------LTMIDVHGAVYEGRPGDMDMATAY-----LASVTNKDHYQGDLKGAVKGA--DVLLGVSA-PRLFTKEIIQSMNKDA---VVFALANPVP--ETTYEEAKAAG------------AAVAGTGRSDAPNQVNNVCVFPGIFRGALAVRASAITEEMKVAAVKAITGLIADDELKEDYVVPGAFD-RRIVPAIAAAVAKTAMEQGIARiRRDPEDIRKEAAER--------------
>UniRef50_O30808(45-425:761) NADP-dependent malic enzyme n=248 Tax=cellular organisms RepID=MAO2_RHIME  E=7e-69 s/c=0.69 id=31% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVISNGTAILGLGNLGAlASKPVMEGKAVLFKRFADVD-----SIDLEVDTEN-------------------------VDEFVNCVRFLGPSfGGINLEDIKAPDCFIIEQRLREvmDIPVFHDDQHGTAIIAAAGLVNALTLTGRDFKTAKLVCNGAGAAAIACIELI----KAMGFNPE----NIILCDTKGVIYKGRTDGMN-QWKSAHAVE--------TDRRTLAEALDGA--DVFFGLSAK-GALSADMVRSMGA---RPIIFAMANPDP--EITPEEVALIRD-DAIVATG----------RSDYPNQVNNVLGFPYIFRGALDVRASTINDAMKIAAAEALANLAKEDvpddvaaayqgnrpRFGPQYIIPVPFDPRLISA-IPMAVAKAAMETGVARKP-IEDLKAY------------------
>UniRef50_C1TL57(52-412:415) Malic enzyme n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TL57_9BACT  E=4e-67 s/c=0.71 id=28% cov=61%
---------------------------------------------------------------------------------------------------------------------------------------------------RLAIVSNGTSVLGFGDYGPEaALPMIEGKSLLYKHFGDID---AIPLCIKS--------ND-------------------MDEIMSFCRLLEPSfGAINVEDVKSPIDFDLVKRLRKelEIPIFGDDMHCSSVVILGSLINALKVVEKDLSLAKIVIVGAGTSAVATAELMLYAGAT----------NVVMLNRRGIIHEDMDDLNGVQRFI------LDRLNPEGIRGGIKEAAKDA--DILIGLTGKVGAFGRDDVALMA---PRSIVFPLSRPEP--EMDPEEAKAAG------------AEVVGCGLIEGPNTMPNLKVFPGITRGLLDVRATGLNFNVQMEAAKEYAANVDPRRLRADHITPFIFS-DELTPRIAEAVAQSCIREGLARISPSP---QEVFENTWKRLYGGY-----
>UniRef50_Q5BXZ0(1-146:166) Malic enzyme (Fragment) n=1 Tax=Schistosoma japonicum RepID=Q5BXZ0_SCHJA  E=5e-44 s/c=1.25 id=34% cov=25%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTSKSECTAERAYRITEGRCVFASGSPFNDVALKisgmEVHFQPGQCNNSYIFPGMGLAITLCQIRPVLQELFVIAAECLADQVEEKDLNVGRVFPPLKNIRNVSLAIAVRVAEYAYSKGLcNRKPQPEDIELYLSKKMYDPNYIP------
>UniRef50_B9TD70(4-153:161) Malic enzyme n=1 Tax=Ricinus communis RepID=B9TD70_RICCO   E=2e-28 s/c=0.87 id=31% cov=24%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VFLGVSG-PGVLSQADVQRMK---PQPIVFTLANPEP--ELRPE-LVREVAPDAIIATG----------RSDYPNQINNALCFPYLFRAALDSGATTINQEMKRACVVALADMArSDARFSKDYIVPGLLDPRLLS-GVTPKIATAAYRSGVARK---------------------------
>UniRef50_P23368(17-567:584) NAD-dependent malic enzyme, mitochondrial n=92 Tax=cellular organisms RepID=MAOM_HUMAN  E=0 s/c=1.34 id=41% cov=96%
--------RHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMKAITDRYGrNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGR------KAKIDSYQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTdGRVFTPGQGNNVYIFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMAfRYPEPEDKAKYVKERTWRSEY--------
>UniRef50_D2VW96(207-759:761) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VW96_NAEGR   E=0 s/c=1.29 id=41% cov=95%
--------------------LYNPMLNKDTAFTVEDREKLGLRGLLPPHVETITHQLVRCLRQFRNFKNPLDKYVYLMSLQGRNQTLFFKLLIDNMVEMLPIVYTPTVGDACLQFDQIWRVAQGMYISLEDKGSISAILKNWEPKQPDIIVVSDGSRILGLGDLGANGMGIPIGKLNLYVAAAGFHPDKTLPICIDVGTNNPGLLEDDLYLGLKRKRVRGQEFFDFMKEFMIAVKTTWPNCLVQFEDFSNDVCFDLLDQYRNEQLCFNDDIQGTGAVIVAGFINAAKITGKRTYQHKLLFMGAGSAATGVADQCVGVMKlqaeEDGLSKEEidamSEHWVYLVDSKGLVTQTRSDyeeMPHHKKKYAKKGDE---TLGNFQSKSLLEIVQKTQPTALIGLCGQSGVFTQDIIEEMAKINQKPIVFALSNPTKNSECTAKEAIEYSSGRAIFASGSPFEDVTYNGKTYQLSQGNNLYIFPALGLGAVVTRSKHVSDVMILRAAQTLADLTSQDRLDNGLLYPSLTNIREIAQKIAVQVGKQSVKEGLSQlteeqlPKSEEEWVKIVKDYVYTPDYES------
>UniRef50_Q0C9G5(87-619:657) Malic enzyme n=22 Tax=Leotiomyceta RepID=Q0C9G5_ASPTN   E=0 s/c=1.30 id=43% cov=93%
--------------------------NYDTANPPYIRKYLRTYGLTPPRAESYEVQKTRCLAQLALKQTPIDKFLYLSTLRKNNVHLFYRLVTDHLRELTPLIYTPVVGEACQRWSEIYQQPEGMYLSWEDRGNLAAVIANWPQHNVEITCITDGSRILGLGDLGINGMGIPIGKLALYTACAGIRPEATLPLTLDLGTSNKTLREDPLYMGSRRDKVTPEEEKEFMDELMAALTERWPGIVIQFEDFKNP--FPALERYRDVYTCFNDDIQGTGAVILGGVINAVKRSGLPCKDHRAVFLGAGSAGVGVAKQIVDFFVREGMTEDEARACFYLVDTKGLVTLDRGDKLADHKVYFARND-----NNGQQFKTLEEVVDHVKPTILMGLSTIGGVFTPEILRKMADWNTRPIIFPLSNPSSKSECDYESAVTHTDGRCLFASGSPFQPFSFTNskgetQTYYPGQGNNMYVFPGIGLGTILSKAVKVTDSMIYASGEALSTALTAEEIDRGLLYPDLTRIRPVSVVVARKVIRAAQEAGVDREtnlrtMSDEALDAWIKTRMYDAH---------
>UniRef50_P36013(85-658:669) NAD-dependent malic enzyme, mitochondrial n=27 Tax=Saccharomyceta RepID=MAOM_YEAST  E=0 s/c=1.17 id=44% cov=96%
-------------PLESFQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKNDFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDSIECRLATYgGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPVCLDVGTNNKKLARDELYMGNKFSRIRGKQYDDFLEKFIKAVKKVYPSAVLHFEDFGVKNARRLLEKYRYELPSFNDDIQGTGAVVMASLIAALKHTNRDLKDTRVLIYGAGSAGLGIADQIVNHMVTHGVDKEEARKKIFLMDRRGLILQSyEANSTPAQHVYAKSDAEWAGINT----RSLHDVVENVKPTCLVGCSTQAGAFTQDVVEEMHKHNPRPIIFPLSNPTRLHEAVPADLMKWTNNNALVATGSPFPPVDG----YRISENNNCYSFPGIGLGAVLSRATTITDKMISAAVDQLAELSPLREgDSRPGLLPGLDTITNTSARLATAVILQALEEGTARIEQEqvpggapgetvkvprdfDECLQWVKAQMWEPVYRPMIK---
>UniRef50_B6DZK1(15-566:568) Malic enzyme n=15 Tax=Trichomonadida RepID=B6DZK1_9EUKA   E=1e-180 s/c=1.15 id=40% cov=95%
----------------GMTLLQDGDLSKGSAFTKEERDRLNLRGLLPYKVFTKDEQAARIRRQFELMPTPLLKYIFLANEREKNSQSFWRFLFTHpPEETMPVLYTPTVGEACQKWATHRQSYRGIYITPEDSGKIKDILRNYPRQDIRCIVVTDAGRILGLGDLGASGLGIPVGKLMLYTLCGQVNPYYTLPIQLDVGTDRKEILNDPLYEGWRHPRLRGDEHLKFVSEFVEAVKEVYGaTCLIQWEDFEMETAFRLLDHFRWRCNCFNDDIEGTAAVTAAAVACAPRIRGvKPLWEQKIIFIGAGSAATGIANLIVDMAQSQsKLPREQLLKNIIMFDSKGMVTADRKDLYPFNKPFQHKMHRYE---------SVLEACQKWGATGIIGVSGCPGLITKEIVEQLCKNTERPIVFALSNPTIKAECTAEQAYKWSNEKALFCSGSPFPDyVAKSGKTLVPSQANNSWIFPAVGFALVATRARHCPSKVFEVAALSLAKLTTKEDLERSALLPPMNLIREKARDIALDVAKYLYDNELATEPIPPhmTLAEFLESQRFNPsgEYEH------
>UniRef50_Q48796(5-541:541) Malolactic enzyme n=97 Tax=Bacteria RepID=MLES_OENOE   E=1e-177 s/c=1.16 id=38% cov=95%
------------------SILNDPFINKGTAFTEAEREELGLNGLLPAKVQALQEQVDQTYAQFQSKVSNLEKRLFLMEIFNTNHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGaAFLDINHPENIQSTLKNAANgRDIKLLVVSDAEGILGIGDWGVQGVDIAVGKLMVYTVAAGIDPSTVLAVVIDAGTNNEKLLKDPMYLGNKFNRVRGDKYYDFIDKFVNHAESLFPNLYLHWEDFGRSNASNILNSYKDKIATFNDDIQGTGIVVLAGVLGALKISGQKLTDQTYMSFGAGTAGMGIVKQLHEEMVEQGLSDEEAKKHFFLVDKQGLLFDDDPDLTPEQKPFAAKRSDFKNAN---QLTNLQAAVEAVHPTILVGTSTHPNSFTEEIVKDMSGYTERPIIFPISNPTKLAEAKAEDVLKWSNGKALIGTGVPVDDIEYEGNAYQIGQANNALIYPGLGFGAIAAQSKLLTPEMISAAAHSLGGIVDTTKVGA-AVLPPVSKLADFSRTVAVAVAKKAVEQGLNRQP-IDDVEKAVDDLKWDPKY--------
>UniRef50_Q5KBK5(22-578:584) Malic enzyme n=3 Tax=Agaricomycotina RepID=Q5KBK5_CRYNE   E=1e-171 s/c=1.08 id=41% cov=96%
------------VALRGGAILNNPRFNKGSAFTHQERSEFALRGRLPYAVDSLEIQVKRAYEQYKSRETNILKNSFLQSMKAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLTPPGEKNMEEdFLDACEGRELELIVVSDGEAILGIGDQGSGGIGISGAKAVIYSLIAGVDPAKCLAITLDVGTNNQDLLNDPLYIGYREKRLRDDRYDQFVDKFVGLVKKHQPECLLHFEDLVSP----MLNDSSEDIgARFNDDIQGTGAVTLAAVQAAISVTKSSLKDQRIVIYGSGSAGLGIARQLRDAIALDSSgSPSEAAKQFWLIDKHGLIKKSLGKdkiRSEIEDEFIRDEGDWGEGET-----GLKEVVKKIKPTILVGTSTQAGAFTEEVVKEMSKHVDRPIIFPLSNPTRLCEAQPKDVSEWSKGKALMSTGSPFDPVDIsdSGEKYIVAECNNALIYPGLGLGSILAKSSKMTDKMIIAGAQRLGQLAPAlvKKNANKSLLPDFGDAQKVNFEVALAVLEQAMEDGVARakdiPEDKDERRKWAENNRWSPGYPNFK----
>UniRef50_A4RWC0(19-512:547) Malic enzyme n=3 Tax=Mamiellales RepID=A4RWC0_OSTLU   E=1e-163 s/c=1.17 id=37% cov=86%
----------------GYATLRDAGTYRGLAT--VDREGRGLRGLLPPNVVEDDVEVRRAREALGQCDGAFESYKQLVALQTTDERTFYKLLRSDTERLLPLLYTPTVGEACLRFGTLIQRPMGVWVSSDDAGNVRELMRNWPRDDVKIAVITDGERILGLGDQGANGMGISAGKSMVYAAC-GVPPSALLPIQIDTGTNNKTLLDDPLYIGLKRERDRSQAYDALLDEVVVSIRERFgPNTIIHWEDFAPRNAFRVLKKYysAPDVVTYNDDIQGTAAVTVSGILASVRAleRGGDVTQQRVLFFGAGQANIGAAELFVLALTKRGVAEADARKRVWLFDSKGLVVRSRASqLSDDKLPFAQDA---------REETDLASAIESIKPTVLVGAAAVPGAFTQKVVKSMSKLNDQPIIFALSNPTSKAECTAEQAYAWSNGRAIFASGTRFPPVRFsAEKTFAPGFANNAFIFPPIALATIVSGAKQVTPDMFLTAAEALAESVDANLFAVGAVYPPVDRI--------------------------------------------------
>UniRef50_Q5K758(82-600:600) Malic enzyme n=1 Tax=Filobasidiella neoformans RepID=Q5K758_CRYNE   E=1e-163 s/c=1.11 id=37% cov=89%
---------------------------------------------------TPAQNLLRLKAHLQNLPTPLLKHVHLSKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYSGPEGLYLNIEDKDRIPEILHQYASKLVappQILVVTDGSRILGLGDLGIGGMGISVGKLNLYVAGGGVNPHGCLPVVLDMGTNNEAVRNDPLYIGLKQPRVGLEEATEFMDAFMAAASEAFPKAVIQHEDFYSEAAFDFLARYKEKYRMFNDDIEGTGSVILAGFLAAAKhaseASGKPLRDHKVVFLGGGSAAVGVAKEMMNFFMMQGLTEDEARERFWLIDTKGLITSTRADVVSGKVA-SHKKFFIRNDTEGKEYPSLESVIEYVQPTALVGLSTTFGAFSESAVRRMAELNQSPIIFPLSNPTSKCELAFSDALEWTDGRVLFASGSPYAPQQFKGTFREPGQGNNFLVFPGIGFGALQAGCKRITTGMITASAIALSEALTPEEKQKGLLYPRLERIRAVSARVAAGVVKQAQEDGVDTNEklrglDIETLTEEMNKAQWWP----------
>UniRef50_C8WQM6(131-497:503) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WQM6_ALIAD  E=7e-87 s/c=0.88 id=28% cov=64%
---------------------------------------------------------------------------------------------------LAVVYTPGVARVCEAIRD--RRDRAFEFTI---------------RKNTVAVVSDGSAVLGLGNIGPEaAMPVMEGKAMLFKRFADVD---AFPICL---------------------------ATQDVDEIVETVERMAPSfGGINLEDISSPRCFEIEERLRKRldIPVFHDDQHGTAVVMLAGLINALKIVNKRMQDVSVVVAGVGAAGVACTKILLAAGV----------GHIVGVDRVGIIERGRHYDNPVKQWYA------ENTNSENRRGTLEEAVRGA--DVFIGVSG-PGILTVGHVKQMARD---PIVFAMANPIP--EILPEVAAGHVR-------------VMATGRSDYPNQINNVLCFPGMFRGALDVRARDITEEMKQAAALAIAECVPEEQLSEQYIIPSPFD-PNVVPAVSRAVQAAAVRSGVARAAAPLELEE-------------------
>UniRef50_Q9ZFV8(35-426:759) NADP-dependent malic enzyme n=153 Tax=Bacteria RepID=MAO2_SALTY   E=3e-85 s/c=0.81 id=27% cov=61%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVISNGTAVLGLGNIGAlAGKPVMEGKGVLFKKFAGID-------VFDIEVDEL----DP---------------DKFIN-VVAALEPTFGG--INLEDIKAPECFYIEQKLRERmnIPVFHDDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGMQ--------KHNIVVCDSKGVIYKGRePNMAETKAAYA---------VDDSGKRTLDEVIDGA--DIFLGCSG-PKVLTQEMVKKMARA---PMILALANPEP--EILPPLAKE-VRPDAIICTG----------RSDYPNQVNNVLCFPFIFRGALDVGATAINEEMKLAAVRAIAELAHAEQsevvasaygdqdlsFGPEYIIPKPFDPRLI-VKIAPAVAKAAMDSGVATRP-IADFDAYIDKLT-EFVYK-------
>UniRef50_C8PMT2(65-444:499) Malate dehydrogenase n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PMT2_9SPIO  E=8e-85 s/c=0.83 id=29% cov=61%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDSTRVLGDGDCsPSGGLGVMEGKCMLMKYLGGVDAY---PICIDSYVKPHEEKKYNFPAGKHCP-----------DKIIDFVRMLEPSVGaVNLEDIQQPDCFKVLDTLREEcdIPVWHDDAQGTACITLAGLLNALKLAGKKIGDSRIVLLGAGASNTTIARLILQ----DGGDP----AKMIICDSQGALHAGRDDIKADARYY--RKWELCQATNPKRISSFDEALKGA--DVLIALSKPgPNTVTKEQIASMG---DKPIVFTCANPIP--EIWPHDAKAAGA----FITG--------TGRGDFPNQINNSICFPGILKGALLVRARKISDGMAIRCAHSIADYSEKKGITPDNIVVKMDD-EDVFAVEAADVAMQAIKEGLA-----------------------------
>UniRef50_D2EFN2(36-399:419) Malic protein domain protein n=1 Tax=Candidatus Parvarchaeum acidiphilum ARMAN-4 RepID=D2EFN2_9EURY  E=2e-78 s/c=0.81 id=29% cov=58%
----------------------------------------------------------------------------------------------------------------------------------------------------IFIITNGTRVLGLGDIGPlASLPVMEGKSLIYKEFGGVN---AIPIPIET---------------------------KEVDEFVNVVKNiSVTSGGIHLEDIESPFCFEVLERLQQelKVPVWHDDQQGTAAAALAGLINATKLADKDLKKSKIVMIGAGAANIALFRILEKYGIDTG--------NIIIGDSKGPLYNGRDDTEIIKTTNRWKYEVMKKSNKD----SVTDADKSFeGADIVIGFS-REGSIKPEWIRKM---NSKPIVFADANPNP--EISPEEAYKA--GADIVSTG----------RSDYPNQINNSLIFPALFRGVLDSKAKKIDDYTAIVAAEELAKFAQERGLKKDYIVPNMEE-RELYPRIASGVAEDLVKRGLS-----------------------------
>UniRef50_D2S3Z0(133-468:500) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=4 Tax=Bacteria RepID=D2S3Z0_9ACTO  E=3e-74 s/c=0.84 id=33% cov=53%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVTDGSAVLGLGDIGPGaAMPVMEGKAVLFKRFADIDAW---PICLDT---------------------------QDVDEIVRTVELIAPGfGGINLEDIAAPRCFEIEARLREKldIPVFHDDQHGTAIVALAAMRNALRVVDKQLEDVKIVVAGGGAAGTAIVHLMLKAGARHVL--------VW--DREGILSPDDERLSPAKLDLAQR------TNPECVRGELPDALDGA--DVFIGVSA-ANVLPVEALARMA---PKAVVFPMANPTP--EVDPVRARQH---AAVVASG----------RSDLPNQINNVLAFPGMFRGLLDARAREISDGMLLAAAEAIASVVKDDQLNANYIIPSV-----------------------------------------------------
>UniRef50_Q27IE1(113-260:260) Malic enzyme (Fragment) n=1 Tax=Hydrilla verticillata RepID=Q27IE1_HYDVE  E=1e-57 s/c=1.53 id=43% cov=26%
---------------SGNSLLRDPRLNKGLAFTEKERDAHYLRGLLPPVFLTQEIQEKKLMTNLRQYQVPLQRYMAMMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQGLYISLREKGKILEVLKNWPERNIEVIVVTDGERILGLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q27113(101-314:434) Malic enzyme (Fragment) n=1 Tax=Trichomonas vaginalis RepID=Q27113_TRIVA  E=6e-57 s/c=1.05 id=41% cov=37%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHLKFVTEFVEAVKEVFGDtCLVQFEDFEMETAFKLLDHFRWRCNCFNDDIEGTAAVAAATLASATHMEGVPdLKNQKIIFIGAGSAAIGIANLIVDMTVsRGGITKEQAFKNIIMFDHRGMVHAGRKDLYDFNKPYMHDMEVY---------GSVLEAVKKFKATCVIGVSGVPGLITKEIVQATLKNAEHPVIMPLSNPTPKAEATPHDVYLWSNAR--------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P48163(1-549:572) NADP-dependent malic enzyme n=129 Tax=cellular organisms RepID=MAOX_HUMAN  E=0 s/c=1.43 id=42% cov=97%
MEPEAPRRRHTH--QRGYLLTRNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTENEELLKDPLYIGLRQRRVRGSEYDDFLDEFMEAVSSKYGmNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTILFQGAGEAALGIAHLIVMALEKEGLPKEKAIKKIWLVDSKGLIVKGRASLTQEKEKFAHEHEEMK---------NLEAIVQEIKPTALIGVAAIGGAFSEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKITKGRAIFASGSPFDPVTLpNGQTLYPGQGNNSYVFPGVALGVVACGLRQITDNIFLTTAEVIAQQVSDKHLEEGRLYPPLNTIRDVSLKIAEKIVKDAYQEKTATvYPEPQNKEAFVRSQMYSTDY--------
>UniRef50_A7MN74(1-566:566) NAD-dependent malic enzyme n=2 Tax=Cronobacter RepID=MAO1_ENTS8   E=0 s/c=1.39 id=84% cov=100%
MEIKHKKNRSLYIPYAGPVLLEFPLLNKGSAFSMEERSNFNLLGLLPEVVETIEEQAERAWRQFEDFKTDIDKHIYLRNIQDTNETLFYRLLENHLEVMMPIIYTPTVGSACERFSEIYRRARGVFISWPNRHNMDDILQNVPIHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPIVLDVGTNNQQLLNDPLYMGWRHPRITDDEYYAFVDDFIQAVKQRWPNVLLQFEDFAQKNAMPLLERYRDEICCFNDDIQGTAAVTLGTLIAASRAAGSQLSEQKIVFLGAGSAGCGIAEQIIAWMRTEgGLSDEQARARVFMVDRFGLLTDNMPNLLSFQSKLVQKRDSLKGWDTQSDSISLLDVVRNAKPDILIGVSGQTGLFTEEIIREMHKHCARPIVMPLSNPTSRVEATPHDILNWTDGAALVATGSPFQPVTVKEKTYPIAQCNNAYIFPGIGLGIISSGALRVTDEMMMAASEALASHSPLVNTGSGLVLPPLTDIQQVSKDIAFAVGKMAQQQGVAVKTSAEALLQAIEENFWLPEYRSYRRTSI
>UniRef50_P43279(98-639:639) NADP-dependent malic enzyme, chloroplastic n=103 Tax=Embryophyta RepID=MAOC_ORYSJ  E=0 s/c=1.41 id=43% cov=95%
---------------SGYTLLRDPHHNKGLAFSEKERDAHYLRGLLPPAVVSQDLQVKKIMHNLRQYSVPLQRYMAMMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKVLDVLRNWPERNIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSACLPITIDVGTNNEQLLNDEFYIGLRQRRATGKEYHELMEEFMSAVKQIYGeKVLIQFEDFANHNAFDLLAKYSKSHLVFNDDIQGTASVVLAGLLSSLKVVGGTLAEHTYLFLGAGEAGTGIAELIALEISKQtKAPIEECRKKVWLLDSKGLIVNSRkESLQAFKKPWAHEHEPV---------TTLLDAVQSIKPTVLIGTSGVGKTFTKEVIEAMASFNERPVIFSLSNPTSHSECTAEEAYNWSQGRAVFASGSPFDPVEYNGKIHVPGQSNNAYIFPGFGLGVVISGAVRVHEDMLLAASETLADQATQENFEKGSIFPPFTNIRKISARIAASVAAKAYELGLATRlPQPRDLEKYAESCMYTPVYRSYR----
>UniRef50_A5F1Z0(5-561:562) NAD-dependent malic enzyme n=261 Tax=cellular organisms RepID=MAO1_VIBC3  E=0 s/c=1.37 id=70% cov=99%
-------KRPLYISYAGPALLSTPLLNKGSAFSAEERASFNLEGLLPEATETIQEQVVRAYQQYRGFESDMDKHIYLRNIQDTNETLFYRLVQNHISEMMPIIYTPTVGAACENFSNIYRRGRGLFISYANRDRIDDLLNNAANHNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNPQRLADPMYMGWRHPRITGPDYDNFVEEFMQAVQRRWPDALIQFEDFAQKNAMPLLERYKNRVCCFNDDIQGTAAVTVGSLLAACKAAGSQLSQQRITFLGAGSAGCGIAEAIIAQMVSEGISDEQARSQVYMVDRWGLLEEGMPNLLDFQQRLVQKKANTQHWTTENNGYSLHDVIRNAKPTVLVGVSGAPGLFSEEIIKEMHQHCPRPIVFPLSNPTSRVEALPSDIIRWTNGEALVATGSPFDPVLHEGKTYPIVQCNNSYIFPGIGLGVLAANARRVTDEMLMESSRALASCSPLAINGHGPLLPPLESIHSVSKKIAFAVAKKAIEQGVAPEVTDEALEASIEQHFWQPVYRRYKRTA-
>UniRef50_C5KT55(256-789:845) Malic enzyme n=6 Tax=cellular organisms RepID=C5KT55_9ALVE   E=0 s/c=1.41 id=47% cov=94%
----------------GLHLMRNPVYNKAEAFTEAEREELGLIGLLPPKVLSIDTQVERCMQQLRTKDTDIGRYIYLEGVHNRNETLYYRLLLDNITDLMPIVYTPSVGQACKDFDRIFRGSRGIYFNISEKGNFKQVIWNSNVRDADIIVVTDGSRILGLGDLGTNGMGIPIGKLSLYVACAGINPGRTVPVTLDVGTNNPDLLNDDMYLGERHKRVDGEEYYAAVDEFVDAVRSRWPGVLIQFEDFTNDHAFPLLKRYQENILCFNDDIQGTGSVALAGVLTAMRAKSEALADQRIVFFGAGSAAVGVADSIVSAMVQQGLTIEEARQRFWLVDSRGLVTSKRGGeLQEHKIRFCRDDEPLE---------SLLEVVQVVKPTILLGLSGQYGAFTEEIIKEMHAHCPAPVIFALSNPTPKAEATPEQLYIWTGGEAWVATGSPFKPVTYNGKIYIPGQGNNMYIFPGVGLAAIVGKFKNIPDTMFYRAAKTLSEKVAEEDLAQGLLYPQINRIRELSHAIAVACIKEALDTGIAQISRPDDLNQLVQDAMWQPEY--------
>UniRef50_C4Q083(33-586:603) Malic enzyme n=1 Tax=Schistosoma mansoni RepID=C4Q083_SCHMA   E=0 s/c=1.34 id=42% cov=96%
-----------FIRLHGIDVVRDPRTNRGTAFTLNERQLLGIHGLLPPSVLTLDQQVSKMMANLKNMNDNLQRYVYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRGLYITVHDRHHIPEILNNWPEPIVKAIVFTDGERILGLGDLGAYGMGIPIGKLSLYTALAGVHPKHCLPILLDVGTDNQELLNDPVYTGIRHKRIRDERYDELIENFMQAVAERYGNhCLVQFEDFGNHNAFRLLERYQDSYCTFNDDIQGTAAVTVAGLLAAGRITKRKLTDNIYLFVGAGEAATGIAQLLATSLQLNGLDEKEALSKIYMFDKDGLLTHSRqeGSLTDHNKVFARDD--------IENIRKLEDAVEKLKPTVIIGASGQGGIFTDAILQQMVKNSERPIIFSLSNPTSKSECTAERAYRITEGRCVFAGGSPFNDVLLkvsgKEVHFQPGQCNNSYIFPGVGLAITLCQIRPVLQELFVIAAECLAGQVDEKDLDVGRVFPPLRDIRNVSLAIAVRVAEYAYSKGIcHYEPQPKDIELYLSQKMYDPNYIP------
>UniRef50_UPI0001926CE9(70-616:621) PREDICTED: similar to predicted protein n=1 Tax=Hydra magnipapillata RepID=UPI0001926CE9  E=0 s/c=1.35 id=43% cov=95%
---------------KGFDILRNPKLNKSTAFTLAERQILGIHGLLPPAINNQKLQMDRAMTQIRRLQTDLQKYILLTQILSRNERLFYQLLMDNIEELTPIVYTPTVGQACQEYGLIFRDPRGLFITIHDIGHIYDIISNWPERRVQAVVMTDGERILGLGDLGCNGMGIPIGKLALYTACGGIHPSACLPIMIDVGTNNTKLLDDPLYIGLRQKRNNTKLYDQLIDEIIQALRQRFgPNVLIQYEDFGSHNSFRLLERYRHKMCTFNDDIQGTAAVALGGLLASLKASHMKLPDHKFLFFGAGGAACGIAQLLVKALINEGLSKEEAVKHIYMFDKDGLVTKNRsvGELTPERALFAHDAEF---------SNSFEHVVKYLKPTAIIGVAGSGRAFTETVCKQMLLNCDKPVIFALSNPTTHAECTAEQAITWTNGKCLFASGSPFEPVTLKdGQVVYPGQGNNVYIFPGLALGVIASGSRIITEEMFLAAAQSLSEQVTDEDIAEGRLYPPLRKIKEVSFEIALKVADIAYKQGIATmIPEPSDKRKLVRSIIYNPNYMSF-----
>UniRef50_D2W4D9(64-631:636) Predicted protein n=3 Tax=Naegleria gruberi RepID=D2W4D9_NAEGR   E=0 s/c=1.24 id=44% cov=95%
---------------SGIDVMNNGLLNKGTSFSKTERDRLGIRGLIPPTVSNIDTQLMRLKERFSTIQTDIEKYQFCTQLHDRNETLFYYFIVNNIKELAPIIYTPTVGKACENFSHIFRKPRGMFFSTLDKGEMKSMVYNWPVEEVDVIVVTDGGRILGLGDLGANGDGIPIGKLSLYVAAGGINPGRVLPVLLDVGTNNEKLFNDPLYLGLRQKRLTGPEYYELVEEWVDAIVSRWPNVLIQWEDFSSDKADALLQKYRDRILCFNDDIQGTASVILSGVLNCLRATGQSFSDitkQKILIVGSGAAGMGVVSGLKEAMKREGLTEEEALKNFYIVDKDGLLTSERLNemgstLSDTAKMFAYARNDMKEG------SSLLDVVKQAEPDILLGMSSQPGLFCEEVLTYFNSACKRkgktPIVFPLSNPTSKAECTAESVFKITDGNAIFASGSPFNPVPLpNGQVIQTSQANNMFAYPGVGLAAVLSGCNTISDNMFYAASKSLAATVSDEALKRKEIYPHVEDIREVSKKVAIGVMRQAYYEGNAKKlkhlpkefiDSDIEMDKYVSTRMWTPKYVP------
>UniRef50_Q875H8(36-614:617) Malic enzyme n=1 Tax=Mucor circinelloides RepID=Q875H8_MUCCI   E=0 s/c=1.20 id=42% cov=99%
-DPRHDKNVHVMHS-RGVNLLHDPLLSKGTAFSIAERERLSIRGLVPPRCQEMDKQLLRIKRNLDACETPLAKFVFLAALHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDRGQMSAMVYNWPHDKVDVIVVTDGSRVLGLGDLGANGMEIPIGKLSLYVAAGGIRPRAVLPVVLDVGTNNQDLLNDPLYLGMSHPRLEGEEYYSFIDEWVTAITSRWPDTLIQFEDFKYPHAYNLLAKYRNRITCFNDDIQSTSSITLAGILASLKSRGmsqEDLSNERIICVGAGSAGVGVCEGIIDCMVAQGRvkSREEAYSKIYMLDQYGLLGNpgvhlpsDEEHGHPYQPRTTKldDRQYCYVKHDLRDQMGLEELVRKVKPTVLLGLTGIQGVXSEEAVREMAKHHERPVIFPLSNPDTHAECTAEEAFKWTDGRAIFASGSPFKDVELpNGKIGRTNQCNNSYSFPvsGLGXGITVSRASRVTPNMFLETARTIADMATPSQLKEGILFPGVSQLREVALNVGTRVCEVAFEEGYATAklEEGEILSEVVRSSAYQPEYVP------
>UniRef50_P37221(37-619:626) NAD-dependent malic enzyme 62 kDa isoform, mitochondrial n=29 Tax=Embryophyta RepID=MAOM_SOLTU  E=0 s/c=1.17 id=40% cov=98%
----TEGHRPTIVHKRSLDILHDPWFNKGTAFSFTERDRLHIRGLLPPNVMSFEQQIARFMADLKRLEVQardgpsdpyvLAKWRILNRLHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYFSAEDRGEMMSMVYNWPADQVDMIVVTDGSRILGLGDLGIQGIGIAIGKLDLYVAAAGINPQRVLPVMIDVGTDNENLLKDPLYLGLQDHRLDGEEYIEVIDEFMEAVFTRWPHVIVQFEDFQSKWAFKLLQRYRNNYRMFNDDIQGTAGVAIAGLLGAVRAQGRPMIDfpkMKIVVAGAGSAGIGVLNAARKTMARMlGNTEiafESARSQFWVVDAKGLITEARENVDPDARPFARKIKEIER-QGLSEGATLAEVVREVKPDVLLGLSACGGLFSKEVLEALkHSTSTRPAIFPMSNPTRNAECTPEEAFSILGENIIFASGSPFKDVDLgNGHVGHCNQANNMFLFPGIGLGTLLSGSRIVSDGMLQAAAECLAAYITEEEVLKGIIYPSISRIRDITKEVAAAVVKEAIEEDLAegyremdsrelRKLDEAQISEFVENNMWSPDY--------
>UniRef50_Q4PC56(80-628:634) Malic enzyme n=3 Tax=Basidiomycota RepID=Q4PC56_USTMA   E=0 s/c=1.24 id=39% cov=95%
-------------------IISDPFPNQDTGFSYEKRDQLGLRGLLPPAKQSLNTQVLRVLHQLRSKSTPLEKHVMLASLRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKIASIVENWPVPagSPRIAVITDGSRILGLGDLGWNGQGISIGKLSLYVAGAGIHPRATLPIVVDLGTNNKKNLEDPLYLGLRRERASTEEYIEFMDEVMHALHTRYPNLIIQFEDFTSENAFRFLERYQGKYPMFNDDIQGTGSVILAGFTNAARIAskesGRPLHDHRILMAGAGSAAVGVGKQLMSFFTRQGLSADEARERIFITDSKGLVTKDRGDKLAEHKVFFARDD-----NAGKQIKDLGEIIDYVKPTAILGLSTIKGTFDENVIRKMATLNKRPIIFPLSNPTDNSECTFEEAVKYTEGRVLFAAGSPFAEIDAasspTGKRMIPGQGNNFLVFPGIGLCAALCKAGRVTNEMITESALALSDALTDQERAEGRLYPNTERIREISRDIAVKCIQMANKQGVTRdggktaAMDEEQLRDWVQGEMWTPKY--------
>UniRef50_B4MPG5(1-260:801) Malic enzyme n=1 Tax=Drosophila willistoni RepID=B4MPG5_DROWI   E=5e-92 s/c=1.31 id=41% cov=46%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGISVGKLELYTALGRIDPQYALPVTLDVGTNNEKLLNDPLYIGIREKRMTGEEYEDFVDEFIDAVTETWsHKTLVHFEDFSTVHAFRFLDKYQNCYTFINDDVQGTASTVLSGFLVIEKITKKPLNEHVFLFAGAGSAATGTADLLVKELIQRGLEKDEAVKNIYLCDEKGLVTKDRPDMLERLKPLAKDTSMA--------IKSVAECVEKLKPSILVGATGVGGIFTEQILQNMAKNHEKPGIIALSNPTDKSECTAEQAYKHTE----------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4QAQ6(16-562:573) Malic enzyme n=23 Tax=Trypanosomatidae RepID=Q4QAQ6_LEIMA   E=0 s/c=1.22 id=40% cov=96%
-------------PGRGVDYLRNRFTNKGTAFTAAERSHMNVEGLLPPSVETLDDQVERYWDQLNRFNEPINRYQLLRNVQNTNVTLYYAILTRYLKQTLPIVYTPTVGEACQRYGDLYQKDHGLYLDVASKGKVRRLIQNLRKTNIDVIVITDGSRILGLGDLGSNGIGISIGKCSLYVAAGGVKPSRVLPVVMDVGTNNLELRNNPLYLGLRKPRCGDADFYALLDEFMEAVKDTWPSAVVQFEDFSNNHCFDMLERYQKKYRCFNDDIQGTGAVIAAGFHTAVKLSKIPLEQQRIVFFGAGSAATGVAESIADLAAETGVKKEGIKKNTFFVDSMGMVATNRGDKL-AKHKLGWARTDIPDADIAS-LKTLEDVVRYVRPTALIGLGATANVFSREIVEFLHSCCPHPIIFPLSNPSSKAEIVPANAYKWTNGDAIVASGSPFPETVVSGRTLQSSQGNNLYIFPGVGLGCCIAQPPYIPQEVLVAAAACLSTLATPDDLAKGQLYPPIEEVRRVSREVAVACIQKLQELGLAKADLPdnrPDLMKLVKTAFWEPRYLP------
>UniRef50_P78715(36-586:592) Malic enzyme, hydrogenosomal n=1 Tax=Neocallimastix frontalis RepID=MAOH_NEOFR  E=0 s/c=1.21 id=40% cov=97%
------KKQVIVTKKTGLDILNDPKLNKGSAFTADEKDRLGIRGLVPPRPQSLEAQYKRCKTNLDKISDPLEKFIYLNHLQNRNETLYYKMILENFVELAPIIYTPVVGEACQKFHKIFTQTRGMYFSTADRGQMSAVAANWPYDDVDVIVVTDGSRILGLGDLGAGGMQIPIGKLTLYVCGGGINPRNVLPIVLDVGTNNKELLNDPLYLGMQHPRLQGEEFHAFVDEWVSAITDRFPKAVIQFEDFMMPNALDLLLKYKDQICMFNDDIQSTGAITLASVLATMRARGGTFADIKketFLCLGAGSSGVGVCETIVDCIVAEGATREEAYAQFYMFDHKGLLGKGRDDLLPSQQVFMRK--------EIEGGKTPAELLKKIKPTCLLGLSTCPKLFNKEMLSYVASYCEKPGIFPLSNPTSRSECTAEEAVEFTDGNLIFASGSPFDPVEWKGKTIQTNQCNNSYSFPGIGLGLVSSRATRVPFETFQVCARVIASLGTPEMLATGKIFPDLDNLRAVSLEVGIEVAKMAERMNIATQFPPKgmDWREWLKHNMWQPEYPH------
>UniRef50_B3WC28(7-546:555) Malolactic enzyme n=40 Tax=Bacteria RepID=B3WC28_LACCB   E=0 s/c=1.23 id=39% cov=95%
------------------QIINDPFLNKGTAFTQAERNQYGLNGLLPPAVQTLDQQVKQAYAQLTTKPTDLAKRQFLMTLFNENHVLFYKLFSEHINEFMPIVYDPTIADTIENYSALFVNPQnATYLSIDDPDHIESALKHSANgRDIRLLVVSDAEGILGIGDWGTQGVDISVGKLMVYTAAAGIDPSQVLPVVLDVGTNNEALLNDDLYLGNRHKRVYGPKYRSFVDQFVTTAEKLFPNLYLHFEDFGRSNAADILNEYKDQITTFNDDIQGTGIIVLAGLLGAMNISKQKLTDQVYLSFGAGTAGAGITSRVYEAFIEEGLSPEEAKKHFYLVDKQGLLFDDMSDLTPEQKPFARKRSEFANADA---LTNLEAVVKAVHPTVLVGTSTVPGTFTESIVKEMAAHTERPIIFPLSNPTKLAEAKADDLIKWTDGRGLIATGVPAANVDYQGVSYAIGQANNALVYPGLGLGTIASTAKLLTDSMISAAAHSLGGIVDPDQPGA-AVLPPVSKLDQFSQTVAIAVAEDAVKHGLNQKP-IKDAKQAVANMTWQPEYRP------
>UniRef50_C4UY62(10-591:595) NAD-dependent malic enzyme 2 n=9 Tax=Bacteria RepID=C4UY62_YERRO   E=0 s/c=1.13 id=41% cov=98%
-------KRKIQTTARGYNVLRDPSLNKGSSFTKEERERLGLNGILPPVITSdMEVQLNRSYNVYHSHKSDLEKHVYMWQLHDNNSTLFYALLQRHMLEMLPVVYDPVVGDAIENYSEIETRPRGIFISINEPELIEEKLRAFGaqPEEIRLLVTTDAEEILGIGDWGSNGIDISVGKLAVYTAAAGVDPHSVIPVVLDVGTNNEKLLNDPAYVGNRHERITGQVYDDFIDSYVKAVRNIYPEAVLHWEDFGSTNARRIINKYRDNFATFNDDMQGTGAIVLAGLLNAVKLSKTPWTEQRVVIFGSGTAGCGIADQIRDQMMKSGLSKEEAISRIWLVDLPGLITSDMtDDLLFYQRDYAKNIADVSsyprtkvdisvesrtrfpemaniliKQNSDKGIIDLAAVVNKVKPTVLIGTSTTPGAFTESIVRDMVSNVERPIIFPLSNPTLLHEATPQHLIEWTDGKVFTATGAPFDDVNYKGITYKIGQANNAALYPGLGFGAIVSKASKITDEMIFAAVEAVASQATLGAEGA-SLLPSNADLRVTSSIVALNVLRTAQSQGLSKVDTNQSDVELVREAAWWPVYVP------
>UniRef50_C1FDT6(69-624:636) Malic enzyme n=4 Tax=Mamiellales RepID=C1FDT6_9CHLO   E=0 s/c=1.18 id=41% cov=96%
----------------GIEVLLNPIYNKGTGFSLAEKERLGIRGLTPPRYFTIEQQCKKIWTNLTEKgKTGMFRWRSMQALQDRNETLFYRLLVDHIEELAPVIYTPTVGEACLQYSRLFRRPRGMYFSADDVGHFNAMMYNW-KNDVSVIVVTDGSRVLGLGDLGAHGMGISVGKLDLYVAGAGIEPSSVLPCVLDVGTDNEELLADPYYFGLPQKRIKGDAFMNIVDEFIQAVKNRWPKALVQFEDFSTDHAMPILKRHRENVLCFNDDIQGTAVVVLAGIYGAMAAMGKSsgaITEQTFVVCGAGSAGMGIANFIHAALVHHGLSPQQAFERFYILDKHGLITNNRE-LKEGEPGVDDLRPFAESRRDLPDGINLREVIESAKPTALLGASTVSGLFTHEILTRMGELNKNPIIMPLSNPTSRAECTAEAAANATEGRAIFSAGSPFDDVSRGGVTMVANQGNNLYVFPGLGLGSILVGSNYISDGMLNAAAEAIPKTLHDGAIRRRAIYPRIADIRDVSVKVAAAVMKQAVDEDrenrggkiahMISREGIEGLERYVRSSMYYPEYRP------
>UniRef50_A1ZAF7(41-581:603) Malic enzyme n=8 Tax=melanogaster subgroup RepID=A1ZAF7_DROME   E=0 s/c=1.21 id=36% cov=93%
------------------------KYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRRLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGVKAICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVGARIPRVKGPEYDELVDEFMESAVKCFGnNTFIHFEDFATPNALKFLEKYQYKYCCFNDDIQGTGATGLAAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATKNIYLMDVNGILTPESPNPPEMGKIFIKSMEPMKD---------MMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFPLSNPTANSECTAEQAFTHTEvrlGRVLFGSGSPFPPVVINGKRYRPAQANNCLTFPGIALAAITAKARYLPNEVFSVVSHELARNTPQELLDEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSnVYPKPDDICEFVKRSLYKFDYRN------
>UniRef50_C5LC75(628-1187:1270) Malic enzyme n=2 Tax=Perkinsus marinus ATCC 50983 RepID=C5LC75_9ALVE   E=1e-175 s/c=1.10 id=34% cov=93%
----------MLVSSRGANLLRDPVLNKGTQFSEIERDELSLRGLIPVRQCTIEMQMSRNMERLRMRDTDLSRFLDLQAIFDRNETLYYRLLVDNLEELHRIVFIPTVGDVCKQFGSVWRFPRGLYFTYSDKGHFQEVVYNCPNEDVDLVVVTDGSRILSLGDLGANGMGVSVGKISLYVACAGLNPGRVLPCILDIGTDNEDLLNDPRYIGEHTRRLKGNDYFAMVDEFVSAVLTRWPNAVIQWEDFSYPNAFMILDNYSNSIRTFNDDVQGTAGVVLAAILAGLKTRaylqskksnanQPRLTKKRYSLDGqrfvfagAGGAAVGIVRLICEALVQEGVPFEEAKSRIWLIDSKGLVSTDRQTSMK---------------------------LRRAEQTLSFRVSAQSGLFSSEVLQAMNANCEYPIVFSLSNPTNCCECTAEEAYRATDGKCLFASGSPMPAYHVPtqnsyklssrvfpetDEHFIPAQASNMYVFPGIGLAASTGNLATIPNQLFYIAARTIASMVTVEEMKTRTLLPPMSKLRETACKVAAQCIIYGSKKGLTRIQTPLDAEVFVKSKMWYPEYKHYLPTA-
>UniRef50_C8R2L8(18-575:584) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8R2L8_9DELT  E=1e-170 s/c=1.08 id=41% cov=97%
--------REIEILARGIDVYDNSFINKGTAFTQEERELFALHGTLPPSIRSLANQMANSRQTCAQKSSDLEKFIYLRSLFDRNVALAHALIASDLERYLPIIYTPTVGEACRHYSSMFRKANGLFFYPGNIDRAEEILRRFVPRQIRVAVVTDNQGILGIGDQGVGGIAICLGKLMLYTQGAGIAPWHCLPISLDVGTDNPELLNDDNYLGWRHPRLRDDDYVAFVQRFALAFKAVFPHALCQWEDFSKQNAFAIRDAYLHRLISFNDDIQGTGAVALAAILAALRSKGEKLGDQVFLVHGAGAGGIGIAEQLAVALQEEGLDETAARARIFTVDRRGLVTTDR-SLEPYKKKFAHDPATLP-WLRETGAGSLAELVRKAGVTVLIGTSGQADAFGRELVQAMLANTARPVILPLSNPTGQSEARPAELAQWSQGRALVATGSPFPPLLSQGRMVRVGQCNNVFIFPGVGLGVLASGAAEVRPEFFTAAARAVADRVAPADLAAGVLLPEVGELREVSRAVAVAVGESAIKAGVAGpcavstyqhHNDPTRLARLIDGMRWRPGYLP------
>UniRef50_B5IJQ0(286-834:840) Malate oxidoreductase n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5IJQ0_9CHRO  E=1e-165 s/c=1.07 id=42% cov=96%
---------------EGTTLLADPRHNRDTAFSREERQLLRLDALLPAAVETLEQQVERAWRGFEALQGELERFVYLDRLRRSNRTLFHAFLQEHIEAALPVVYTPTVGRVIQGYSHSHQPSDlGVFLTPEQQDRLPELLRQASDGPVDLLLITDAEGILGLGDQGVGGIHICQGKLAVYTLCSGLHPSRVLAVVLDVGTDNPQLLADPLYPGRRQPRLRGEAYDRFLDAVVAAATQVFPGVFLHWEDFGKSQARRVLDRYRDRAPSFNDDIQGTSGVAAAVVLAACRGLNAGLTDQRIVIFGAGTAGCGIAERLLRLLQAAGLSADQARERLWALDRHGLIVEGQPGLGGPAGGLARAAQEGAHYQRDADgRIGLLEVVRQVRPTVLIGTSTVAGAFSQAVVEAMAAGCERPLILPLSNPTALAEATPADLLAWSGGRALVATGSPFAPVVWHGRERVIGQCNNCFLYPGLGFAAVAVGAERVSEAMVDAALEALAAAIPAAQDPEAPLMPSLRQVRAVSRAVAEAVATTAVAAGLARlATTPEEARRCLDQVTWEATY--------
>UniRef50_C5KT56(1-344:395) Malic enzyme n=5 Tax=Eukaryota RepID=C5KT56_9ALVE   E=1e-123 s/c=1.29 id=43% cov=61%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MYLGERHKRVDGEEYYAAVDEFVDAVRSRWPGVLIQFEDFTNDHAFPLLKRYQENILCFNDDIQGTGSVALAGLVSAMRVKKEKLEDQRIVFLGAGAAAVGIADCIVAAMVHDGLSPEDARKRFWFVDSRGLVTwKRGGNIQDHKVPYCRDDAE--------PMTSLLEVVKAIKPTVLLGLSGQSGSFTEDIIKAMYANCPQPVIFALSNPTPKAEATPEQLYTWTDGNAWVCTGSPFGPVTYNGKVYQSGQGNNMYIFPGVGLAGILGKFKWIPDSMFYTAAKTLAERVTEEDIARGTLYPCLTRIRELSHDIAVSCIKEAFDLGIACIERPADLDKFVWDHMWKPEY--------
>UniRef50_O34962(32-406:410) Probable NAD-dependent malic enzyme 4 n=82 Tax=cellular organisms RepID=MAO4_BACSU  E=2e-85 s/c=0.85 id=32% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVTDGTAVLGLGNIGPEaALPVMEGKAVLFKSFAGVD---AFPIALN--TND----------------------VDKIVETVKLLEPTFGG--VNLEDIAAPNCFIIEERLKKetNIPVFHDDQHGTAIVTVAGLVNALKLSGKSMSSIKVVANGAGAAGIAIIKLLHHYGVRD----------IVMCDSKGAIYEGRPNGMNDVK-----NEVAKFTNQDRKDGSLKDVI--VDADVFIGVS-VAGALTKEMVQSMAKD---PIIFAMANPNP--EIMPEDAREA--GASVVGTG----------RSDFPNQVNNVLAFPGIFRGALDVRATHINEEMKIAAVEAIASLVSEDELSADYVIPAPFDKRVAPAVAKAV-AKAAMETGVARITvDPEEVAE-------------------
>UniRef50_C7HAW1(130-467:488) NADP-dependent malic enzyme n=3 Tax=Firmicutes RepID=C7HAW1_9FIRM   E=2e-84 s/c=0.93 id=30% cov=53%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSNGTAVLGLGDIGPEaGLPVMEGKAVLFKEFGGVD---AFPICID------------------------AHDAASVIAACKAIAPTFGG--INLEDIKSPECFEIEETLEREldIPVFHDDQHGTAIVVTAALINALRVVGKKMEDVHIVLNGPGAAGTAIIKMLMTAGAKD----------IVAVDQFGTLYKGCNSAE------AHKNWLGEVTNPRQIKGGLKEAIEGA--DVFIGVS-RPGILTTELCKTMNKDA---IVFAMANPTP--EIMPDDAK--AGGVRVMATG----------RSDFPNQVNNVLCFPGLFKGALSVRARDINDQMKLAAAYAIADLITDADRSEENIIP-------------------------------------------------------
>UniRef50_B7L0I3(39-423:777) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase n=73 Tax=cellular organisms RepID=B7L0I3_METC4  E=5e-75 s/c=0.74 id=28% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVLSNGTAVLGLGDIGPlASKPVMEGKAVLFKKFAGID-------VFDIEVDQKDV-------------------DKLVD-VVCALEPTFGG--INLEDIKAPECFEVEERCRERmnIPVFHDDQHGTAIIVAAAVLNALELAGKRLSDAKIV--------TSGAGAAALACLNLLVSLGATRENITVTDIKGVVYKGRAELMDrWKDVYAQ----------ETDARTLAEVIPGA--DVFIGLSA-GGVLKPEYLEKMA---EKPLIMALANPYP--EIMPDLAEQA-RPDAMICTG----------RSDFPNQVNNVLCFPYIFRGALDVGAHKINEEMKKAAvkaiaalaretpSDVVARAYGGEARPFGPrsLIPSPFDPRLI-VRIAPAVAKAAMDSGVAGRPV-ENIDAYAES---------------
>UniRef50_D0KVP8(96-476:478) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=1 Tax=Halothiobacillus neapolitanus c2 RepID=D0KVP8_HALNC  E=3e-72 s/c=0.72 id=29% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVISDGSAILGLGNLGAlASKPVMEGKALLFKKFANIDA-----IDLEVET---------------------QEPMELID-TVRRLGASFGG--INLEDISAPRCFEIEAALIEamDIPVFHDDQHGTAIIIAAGLVNALHIQNKKLEDIRLVLVGAGAAGTATLRLLL----EMGLNREQLR----VVDKVGVLHSGLTDLPEHHAAVVADTDD----------RTLEDALRGA--DVFIGLSA-PNLLSAEMLSSMA---DQPVVFALANPDP--EIRPELAHSVRD-DLIMATG----------RSDYPNQVNNVLAFPFIFRGTLDCRASRITANMKIACVEALAALAREpvpqsvlaaynldsLTFGAEYILPKPFDPRLI-ERLPAAVAAAAERDGVAR-----------------TAYRPYPRVT-
>UniRef50_B4SG57(41-394:409) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=4 Tax=Chlorobium/Pelodictyon group RepID=B4SG57_PELPB  E=7e-69 s/c=0.75 id=28% cov=50%
---------------------------------------------------------------------------------------------------------------------------------------------------QVAIVSDGTAILGLGDLGPEaAMPVMEGKAIIFKEFADID---AIPLCINS-TDVEEIIQ-----------------------FCKMIEPSF--AGINLEDISAPRCFEIFERLEKElsIPVFHDDQDGTAIVTMAAIINACRITGKKIGDLTVIINGAGAAGIAIARLLIHAQVKEVM----------LVDTQGALYEGRPGMNSIKQGIAAISNKAKHQGDLQSSM--------VGADVFVGVS-IGNIVTPAMVEGM---NSSPFIFAMANPEP--EIMPDLAYKA--GASVVGTG----------RSDLPNQVNNALVFPGLFKGLFLSGIKKVTPEIKMAVATSIA----------------------------------------------------------------------
>UniRef50_Q61829(99-275:332) Malic enzyme (Fragment) n=1 Tax=Mus musculus RepID=Q61829_MOUSE   E=1e-57 s/c=1.28 id=34% cov=31%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKGRASLTEEKEVFAHEHEEMK---------NLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSSPTSKAECSADECYKVTKGRAIFASGSPFDPVTLPdGRTLFPGQGNNSYVFPGVALGVVACGLRHIDDKVFLTTREVISQQVSDKHLQEGRLYPPLNTIRGVSLKIAVKV---------------------------------------
>UniRef50_C5JAR0(35-245:440) Malic oxidoreductase family protein n=1 Tax=uncultured bacterium RepID=C5JAR0_9BACT  E=2e-40 s/c=0.81 id=27% cov=31%
------------------------------------------------------------------------------------------------------------------------------------------------------VVTNGTAVLGLGNIGPlAAKPVMEGKGVLFKKFAGID-------VFDIE-------------------ISEADPDKLV-EIIASLEPTFGG--INLEDIKAPECFVVESKLRERmkIPVFHDDQHGTAIIVGAAVLNALRVVGKKIEEVRLVCSGAGAAALSCLDVLVSLGMK--------REHIIVCDIEGVVYEGRTSLMdPYKIRYAQDRD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9TLV5(79-260:606) Malic enzyme n=2 Tax=Proteobacteria RepID=C9TLV5_9RHIZ   E=2e-35 s/c=0.84 id=31% cov=28%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DARTLADVIGGA--DVFLGLSA-AGVLKPELLKQMA---EKPLIMALANP--KPEIMPEEARAARA-DAMICTG----------RSDFPNQVNNVLCFPYIFRGALDVGATVINEEMKLAAVRAIASLAREEpsdvaaraysgdtpTFGPDYIIPSPFDQRLI-LRIAPAVAKAAMETGVATRP-IEDMEAYLD----------------
>UniRef50_C5JVF7(17-224:260) Malic enzyme n=1 Tax=Ajellomyces dermatitidis SLH14081 RepID=C5JVF7_AJEDS  E=5e-33 s/c=0.70 id=41% cov=34%
----------------------------GMSVPDDERQTFKLHGLLPSNVQTLDE---------RGRES----------------------------------------------SRTFRPPEGCFLNIRDQDRIDECLANLANfgasgEEIDCIVITDGERglmILGIGDQGDQGeqrdLDFP-GQAGPHGAMG----TRQLPVVLDCGISVKNAL-------------SGRNTMNFVDKFVKAARKS--------EDFPLPNAQRT-----------GDDIQGTGCVTLAALLAALQVSKVKLTDDVpVVCFGAGPAGVSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P45868(22-577:582) Probable NAD-dependent malic enzyme 2 n=131 Tax=Bacteria RepID=MAO2_BACSU  E=0 s/c=1.24 id=44% cov=98%
---KKTKEGHLETTLRGKEVLSIPTLNKGVAFSLEERQELGLEGLLPPTVLSLDQQAQRAYEQFQAQPDRLRQNVYLSDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYLSIDNIDGIEKAFENLhaTAGDIDLIVATDSESILGIGDWGVGGINIAIGKLAVYTAAAGIDPSRVIPVVLDVGTNNEKLLNDPLYIGNKHERVQGERYEAFIDAYVKAALKFFPKALLHWEDLGNKNARNIMKKYNHEILTFNDDIQGTGAITLAGVLAAMKKTGASIKDQRVVIFGAGSAGIGIADQIRDTMVLAGLSEEEANKRFYTLDYRGLLTEDIEGILDFQKPYLRNADEVKDWKrDEKGQIPFDEVVRQAKPTILIGTSGVSGAFTEEIVKEMASHVDRPVIMPMSNPTHLAEAVPEDLFKWTDGKVLIATGSPFDNVEYNGVSYEIGQSNNAFAFPGLGLGSIVAEARIITPAMFAATADAIAEMVDLETPGAG-LLPSIDKLQEVSIQVAIAVAEAAIKDGVANR-QPEDVKQAVLDAMWTPEYK-------
>UniRef50_C6N6R2(7-568:569) Malate dehydrogenase n=2 Tax=Legionella RepID=C6N6R2_9GAMM   E=0 s/c=1.22 id=50% cov=96%
-----------------YNLLNNSRLNKGTAFTQSERDEFALHGLLPPHIGTLANQEQRRYEGLTSLQTPLEKYSFLRDLQDTNETLFYSLIAHHIEETLPIVYTPVVGEGCQQFSEVFRKPRGLFLSYPNKDLIDKILAHPRYDVIKCIVVSDGERILGLGDQGAGGMGIPIGKMALYTALAGIPPEYCLPILLDVGTDNEERLNDPLYIGWRNRRIRGPEYDEFVDMFVSAVKRRWPNILLQWEDFAGVNAARFLERYRNQLCTFNDDIQGTAAMATGTLLAAINVTGIPMKEQKVVFFGFGGTGHGIAQLIRAAMRDAGLTDQEAGERIYAVDRYGLLVEGGKGLSVDQESFAHTRSEVAKWQvANSEDISLLDVVRNVQPTVLIGVSAQQGAFTEEVVRTMAKNTARPVIFPLSNPTSHSEATPQDIIDWTDGRALIGTGSPFAPVKINGKEVHIDQTNNSYIFPGLALGIIASHAKRVSDAMIKAAALALAARSPAREDKEANLLPPLSSLRIISLDVAKAVGKQAIAEGLAGVDE-AGFVKELAANIWEPVYKTYIR---
>UniRef50_C6N039(10-569:584) Malate dehydrogenase n=2 Tax=Legionella RepID=C6N039_9GAMM   E=0 s/c=1.23 id=46% cov=99%
---EHTGERYIETSLCGKPLLTTPQLNKGTAFTNEERKEFGLLGKLPYRVETLDEQVKRAYLQYSSYTTRLKQNIYLNNLHDKNQVLFYKLLHRHLGEMLPTIYTPIVGTAVKRFSLEYRQPRGLYIAHSDKNYIEEIIKNRSNPEIDVIVVTDGEGVLGIGDQGIGGMDIPVAKLMVYCLCGGIDPTRTLPVFLDAGTNNQDLLNDPMYLGCRHPRISGAAYDDFIATFVHEIHKQFPNAFLHWEDLGRGNARRILDQFQNELCTFNDDIQGTGAVTLAALLAACDVTGSKLQDQRIVVFGAGSAGTGISDQIIDLLMRDGLSVEEAYQRFWLIDRQGLLLNNDLDLTEAQKPYARDRKEVAKWHiNEKQHPSLTDTIRHVKPTILIGCSAQPGAFSQDIIETMTKTCERPIIFPLSNPDEKCEAKPSDILTWSKGKALIATGTAFAPIEYHKRMVQIAQCNNALVFPGIGLGVLAVNATKLTKEMILAAAETLCKFAPSKKDSFLPLLPSLDDAQAVAKAIAVAVARSAIESGHAQRNQDADLEKLVDNLFWKPRYLPFKR---
>UniRef50_B4J7G0(52-587:608) Malic enzyme n=1 Tax=Drosophila grimshawi RepID=B4J7G0_DROGR   E=0 s/c=1.24 id=40% cov=93%
----------------------DPKYNKGLGFTHEERQKLSVIGLLPCAYRTEAEQLYAANVNFNSQESNMGRYLYLRTLRSRQERLYYRFVSEYVEKVMPIIYTPTVGAVCQRFSSIYSSSMGLYVCKYDRGNMYHVLNNWPGKDIRAVCVTDGERVLGLGDLGAHGMGIAVGKLDLYTALGKIPPQYLMPVVLDVGTNNKMLLADPLYIGVREKRCTGKEYEDLVQEFMDGVVSSWGHeTLIHFEDFATPNAFKFISKYQDNYCYFNDDIQGTAATGLAGFLAVERITKRPLNEHLILFVGAGSAALGIGKLVVKELMSRKMSAEEAMKNIYLMDSFGVVTKDRKDfILPDIEPFAKDMPPLTD---------LEQVVKELKPSILLGATGQGGIFTENVLRLMAQDQKQPAIFACSNPTSKAECTAEQAYNFTEGRALFASGSPFPPVLMDGKRLTPSQANNAFAFPGVALGAMCAKPHTIPDEVYLITARTLADYAVEEYPDSVILYPPVMDAANVAFKVGVAVAEYLFDTGLATKfPIPDDVCAFVSGYQYN-----------
>UniRef50_Q4S0L0(49-677:694) Malic enzyme n=4 Tax=Eukaryota RepID=Q4S0L0_TETNG   E=0 s/c=1.05 id=38% cov=95%
----------------GYDITRNPHLNKGMAFTLEERLQMGIHGLLPPCFLSQDVQVLRVMKSYETRSNPLDKYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYGLAFRRPRGLFITIHDRGHIATMLNSWPEEDIKAVVVTDGERILGLGDLGSYGMGIPVGKLALLHRLRRRAAaavppgaagrGHRQPGSVPGGVCVQVLLDDPLYIGLKHKRVRGKDYDGLIEEFMQAVTDKYGmNCLIQFEDFANSNAFRILNKYRNRYCTFNDDIQG-GQQAARGLAEGGRPAGPPAgltslsfrhgvrgcgrslgrsEDHQEPAQGAhlcvpggrrgeaappalplCQAALGIAHLLIMAMAKEGLSKEEAARRIWMVDSRGLIVKGRSHLNHEKEEFAHDHPHL---------RTLEEVVHTIRPTAIIGKSsltvltveaplplssgvaAIAGAFTEKIIRDMAAFNERPIIFALSNPTSKAECTAEQCYTLTEGRGIFASGSPFDKVVLAdGRTFYPGQGNNAYVFPGVALGVIACGVRHISDDIFLTTAEvsrstashwnrAIADMVTEENLAEGRLYPPLSTIREVSFKIAVQVISYAYKHNVASvYPEPKDKEAFVLSHIYSPNYDSF-----
>UniRef50_A4RZA5(9-555:555) Malic enzyme n=2 Tax=Ostreococcus RepID=A4RZA5_OSTLU   E=0 s/c=1.19 id=36% cov=95%
---------------SGVELLRSGKYNKGMSFTRDERDRLNLRGLLPPAVFDQSVQVERVIERLRRVTNDVEKHAWLASLYERNERLFYRVVKDHLEELLPILSAPTVWQVCAEFGLMYRRPRGLYISIKDRGSVYRLLKNWPVRDVKAIVLTDGQRVTGLGDLGVQGMGTAVGKSTLFTALGGLDPADVLPICIDVGTDNQALLEDKFYIGLRQKRTGGEEYDDLLDEVVYGLKRRFgPRVLLCFEEFSNKNAKRLLDRYNSNSVAYCDDLQGIAATTLAAIISALPQMGGSLREQRFLFAGAGETGAHTADLLATYIsQQHGISLPEARENIYFIDRKGLVTRDRaqreDDLEIHKLPYAHDME---------GAASVRESVELIKPTALIGvLLKDEKLFTEDVLRAMAKHSEKPLIMALSRPSALRECTAKEAYEATNGKCIFVGGCKSTPFEYAGREIAPSECSTEYVFPGLGLGLTIAEGTRVRDSLLMEAAEVVANSATPGDIARGAVFPRKRHIPDVSARVAARVAGKAFASGLsALPGKPMDWLRLAKSWMFDPTYRPY-----
>UniRef50_A8NR40(3-541:557) Malic enzyme n=2 Tax=Agaricales RepID=A8NR40_COPC7   E=1e-180 s/c=1.18 id=40% cov=87%
--------------------------------------------------------AQRVLAQLRSKHNGLEKYIYLNGLKERDPNLFYELLLANMLEMVPILYTPTgllqVGDACSNYSHIWRRPEGLYVTIENKGHIREVLRTWPAGQaARIAVVTDGSRILGLGDLGANGLPISIGKLDLYVAGAGIKPTTTLPICLDLGTNTQRFLEDPLYIGVRRKRPATAEMDEFMHEFMEAMREVFPQLLVQFEDFSTDNAFRYLDLFRNQYRVFNDDTtypRGIGSVILSGFLNAARIaseaAGTPLTEHRILFFGAGSAGIGVAKQLLSFFTLQGMSVEEAKKRIYTVDSKGLITADRKGLQEHKIFFARTDYQ------GPPLTNLVDVINYVKPTALLGLSTVRNAFPEEVVRLMASLNTRPIIFPLSNPVSLCEVDYADAIKWTNGSVIFASGSPYKPVEYEGKTYEPGQGNNMYVFPGIGMGAILSKARHVTDSMVEQASIALASSLTPEEKAAGLVYPRLVRIRDISAQVALAVIRAAQkdhalqnvdENSLFRNLSDDALLEYIKAKQWQP----------
>UniRef50_B0DZ00(7-606:613) Malic enzyme n=5 Tax=Agaricomycetes RepID=B0DZ00_LACBS   E=1e-171 s/c=1.00 id=42% cov=98%
-------KPPLQLALRGDSLLTSPRFNKGAGFPANERTAFGLIGRLPYRTNTLDEQCERAYEQLTSRDSAIRKNTFLQSLKDQNWTLYYSLLARHLKELVPVIYTPTEAEAIANYSHLFRRSEGLYLTFPSQERMEEdFLEQTEGRDIDLFVCTDSEAILGIGDQGV---GISTAKSVMYTLVGGLDPSRSVSVVLDVGTNNEELLNDPLYVGWPSKRIRGEEYDNFIDKFVQLVRKCHPHSLLHFEDFGVTNAHRLLDRYRESHAAFNDDIQGTGAVTLACILAAIGISsrssksgqGKRLSDQRYVILGAGSAGMGIAVQLRDAMVaDDGVSRAEANQRFWLVDRQGLLFDSGTALLSqtdsaERREFIRPESEYWEElvvGGREKTIGLLEVVKRVKPTVLIGCSTAAGAFTEDVVKAMAAALQaedpgaRPIITPLSNPSRLVEATPENIMRWTKGRALVATGSPFDSVHLEvdGKKKEIAECNNALIYPGLGFGAILSQSRQMTDTMLIAGARRLAALSPAITLARraeekgeeyeyngEALLPDFGEAPEVNFEVAAAVAEQAVKEGVAQVDwavglGSEQLTNVVRerghERIWLPRYADY-----
>UniRef50_Q2HCG7(25-563:586) Malic enzyme n=1 Tax=Chaetomium globosum RepID=Q2HCG7_CHAGB   E=1e-169 s/c=1.11 id=43% cov=89%
---------PLECALKGTVLLNHSYFNKGSAFTKEERRDFELSGLLPQSIQTLDQQVQRAYEQYSARPDDLAKNTFLTSMKEQNEVLYFK--------MFSVVYTPTEGDAIENFSRLFRRPQGVFLNVHDCDRVHHDLSLWGmPDDIDYIVVTgatfhprarsrlryqltklDGEEILGIGDQGCGGILISVAKLALMTLCAGIHPNRVLPVVLDCGTDNETLLNDPLYLGLREKRVR---------------------------------ARRLLDRWRPDIPCFNDDVQGTGCVTLAAIFAGLHVSKTKLGDLRMVVFGGGTAGVGIADQVRDAIATErGITKEEAARQIWLIDKPGLLTNQVERLSDAQKTYARS-EDWTDKETD-----LLGVVKEVKPNVLVGTSTVPKAFTEEIVREMAAHVERPIILPLSNPTRLHEAAPANLLSWTNGKALVATGSPFKPVKGPwgpdGKEVQIevAECNNSVVFPGIGLGSVLCRARLVTDKMLIAAVNGVVGHSPALANDTAPLLPGVDKVREVSVRVAREVIQAAVEEGVATEEGIPkdekELDGWIMEQMWDPVYRP------
>UniRef50_Q5CS07(53-613:614) Malic enzyme (Fragment) n=3 Tax=Cryptosporidium RepID=Q5CS07_CRYPV   E=1e-167 s/c=1.06 id=37% cov=96%
MAPSLRKKP---IELKGIELLRNPFYNKGLSFTMEERKEYGLEGLLPAKYETIDEQVSRLWTAINKIDSNIGKYTFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTVGEGCIEFSRNPTirnwLGSGLYLNKSHKGRIYEILKDFKSDDIEIIVLTDGGRILGLGDLGLNGMGIPMGKLSLYITLGGIDPSKVLPISLDIGTNTNDILSDKYYLGICEKRIDNDEYFPLMDEITKAIFKRWPNTVLQWEDLTTSRAIDILDIYQDKFRCFNDDIQGTASIVLAGLVSSLKIAGKNFEDQRILICGAGSASIGIVNLIIKSMEIKGIPYQSALEKFWLVDSKGLITNSRDlnSLDKFKVPFIRK-------NIDRSITDLVEIVELVKPTILLGVSGQGGIFNEQVIKTMALNVERPIVFALSNPTNKAECNASDAYKWTNGKVIFASGSPMNPIKAiDGTEFIPSQCNNMYVFPGIGLAAQIGQLSHIPDICFIEAAYSVSNFIHIDSNSN-ILFPPLTASvgREISASIAADIILRAKEMNIINKsvcpdlplDNRENILNYIKDRMWLP----------
>UniRef50_A6XP71(109-655:669) Malic enzyme n=3 Tax=Mucoromycotina RepID=A6XP71_MORAP   E=1e-164 s/c=1.06 id=39% cov=92%
----------------------------GTATPTELRSALHLQGLTPAKVESFELQKKRALAQLRSKSSDIEKYVFLAWLRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPflappgQPDGLFLSINDLPNLTQIIQNYkpfpqdPSLTPQIAVITDGSRILGLGDLGVGGMGIPVGKLQLYVAGAGIDPRRTLPITLDLGTNNEDKLKDEFYLGLREKRAGDDKFFPFVDAVIEALTSLYPKLLIQFEDFSSEHAFQLLDKYQPKKFCFNDDIQGTGAVILAGFMNAINLAGIPAKDHKILFFGAGSAAVCVAKQLAAYFVNDhGMTEDEAREMVWLVDSKGLVTLDRGDKLAEHKLYFARKD-----NAGSQYPSIASVIEHVRPTALFGLSSQSGAFSEDVLKSMATLNQRPIVFPLSNPAYQAECSFEQAMIHTKGKVIFASGTAFPKYTDPNTGLisAPGQGNNMYIFPGLGLGGILAQPETISDRLIYSAARACANALTVEERSQGLLYPVLPRIRQVSAEVAAAVVTEAVAEGTATNEeaiklvkshDKAALLNFVNSNMWT-----------
>UniRef50_C4Q3C2(16-522:527) Malic enzyme n=2 Tax=Schistosoma mansoni RepID=C4Q3C2_SCHMA   E=1e-163 s/c=1.14 id=32% cov=88%
----------------GIEILRDPRTNKGSSYTLHERQLLGIHGLLPPNPQNQDVEGQRVISNLYQLDDNLSRYMMLMSLQDLNEKLFYRTIRTHLEYCLPLIYTPTVGLACLNFGFVFRRPRGIYITIQDKGHIFTLLKNWPADTIKTVVMTDGERILGFGDMGANGMAIPLSKAVLYTALGGLQPNHCLPVMLDVGTNNEKLLEDEFYVGLRRKRASGEEYISFMDEVVESLSAQF-------------------------CCGYCIRSD-----------NCVQVTQKKISENNYLFYGGGGASIGIARLLVQAIMEEGFSEDEAKSRIFIMDSKGLIVTSRE-LSAAKSEFARSDYP--------QIDSLLEAIRFIRPSVLIGASAQSGAFTRDILRELSTIHKTPIIFVLSNQSNLGECTSQMAYKATEWRCIFVSGSPSEPVRTPdNRILKPSQGNNCYVFPSLVNALSLAAIRPLTNKLLLTAAKKLSELVTDDDIRQGSMYPSIARLPTITKEVSCAIMEQAYKDKIAFFtPEPDNKMEFIESYYYDHRYINF-----
>UniRef50_C4JEJ1(19-524:625) Malic enzyme n=2 Tax=Onygenales RepID=C4JEJ1_UNCRE   E=1e-158 s/c=1.11 id=39% cov=85%
------------------------------------RKYLRTYGLTPPHVDSYEVQKTRCKQSILTAMSRLgpvsspDAGTDTIDLHSCG----WRSLSEVVGDL------PTTR------------------SYEDRGNIAAILNNWPQPNVEITCITDGSRILGLGDLGINGMGIPIGKLALYTACAGIRPEATLPLTLDLGTSNKALREDPLYMGSRRDKVTPAQELEFLDELMVALTEKWPGIVVQFEDFKNP--FPALERYRHKYTSFNDDIQGTGAVILAGVMNAVKKSGIPPRNHKAVFLGAGSAGVGVAKQIVDFFVREGMSEDDARACFYLVDTKGLVTADRGDKLAPHKVYFARTD-----NAGQQFKTLEDVVNYVKPTMLMGLSTLGGVFTPQILKKMSDWNRTPIIFPLSNPSANSECNFESAIVNTDGRCLFASGSPFQPFSYTNhagetKTHYPGQ--------GIGLGTILSKAVEITDSMIYASAQALSTALTKEETDLGLLYPDITRIREVSVTVARGVIRAAQDAKVDRETgirslSDSDLDAWIKTRMYNPH---------
>UniRef50_A7T6B8(12-365:365) Malic enzyme (Fragment) n=1 Tax=Nematostella vectensis RepID=A7T6B8_NEMVE  E=1e-136 s/c=1.38 id=45% cov=62%
----------------GTDIMRDSHLNKGLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDLEKYIQLMALLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGHIRDIVSNWPTTEVKAIVMTDGERILGLGDLGCCGMGIPVGKLALYTVCGGIDPEGCLPVMIDVGTNNEELLDDPFYIGVRQKRCNTEDYDELIDEFIQAALQR--------------------------------------SV---------------LKDEK--------AAIGIANLLVLAMKKEGLTEEQAKKKIWLVDSRGLVVKDRDcgGLTEQKLAFAKEHEYI---------DNLTDVVKHIKPTTIVGVAAVPGAFTEEICRDMASFNDRPVIFALSNPTSKAECTALNCYTWTE----------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1IKG6(37-419:432) Malic enzyme (Fragment) n=5 Tax=Magnoliophyta RepID=D1IKG6_VITVI   E=1e-132 s/c=1.24 id=40% cov=68%
-----------HIRTSGYTLLRDPHHNKGLAFTEKERDAHYLRGLLPPAVLNQDLQEKRLMHNLRQYKVPLQRYMAMMDFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKILEVLKNWPERSIQVIVVTNGERILGLGDLGCQGMGIPVGKLSLYTTLGGLHPSVCLPVTIDVGTNNEQLLKDEFYIGLKQRRATGQEYAELLHELMCAVKQNYGERVLIHVNFANHNAFELLAKYSKTHL-------GTTSVVLAELIASLKLVGGSLAELTFLFLGAGEAGTGIAELIALEISKQtKAPLEETRKKIWLVNSKGLIVHSRmESLQHFKKPWAHEHEPIRA---------LVDAVQSIKPTVLIGSLGIGKTFTKEVVEAMTSFN-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5IRR3(42-419:444) Malic enzyme, NAD binding domain protein n=1 Tax=Thermococcus barophilus MP RepID=B5IRR3_9EURY  E=8e-96 s/c=0.93 id=31% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDGSRILGLGNIGAlAGLPVMEGKALLFKHFGGVD---AFPIMID--------EQDP---------------DKFI-EIVKAIAPTFGG--INLEDIASPKCFYILERLRKEldIPVFHDDQQGTAAVVLAGLLNALKVVGKKLDETTIALFGAGAAGFATLRILTKAGVKPG-----NVRVVELVNGKPTVLTSDMDL---EKLFPYRGWLLSKTNAEEITGGPEEAVNGA--DVLISFTKPgPGVIKPEWIAKM---NDDAIVFPLANPVP--EILPDEAKKA--GAKIVATG----------RSDYPNQINNVLGFPGIFRGALDVRAKTITDTMIIEAAKAIASVVGDEELTEEYIIPSPLN-PEVYPREARAVAEQAMKEGVARR---------------------------
>UniRef50_C4L8H3(113-466:477) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=1 Tax=Tolumonas auensis DSM 9187 RepID=C4L8H3_TOLAT  E=1e-93 s/c=0.98 id=27% cov=57%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDGTAVLGLGDIGPEaAMPVMEGKAALFKQFAGVD---AFPICLDT-KDTEEIIM-----------------------IVKALAPTFGG--INLEDISAPRCFEIEERLKQEldIPVFHDDQHGTAVTVLAGFLNALKVCEKNIADVKVVLVGIGAAGIAVSKMLLNAGV----------KNLIGVDRNGAIHRGEPYSNESWNEYAR------LTNPDNLQGPLSDVIEGA--DVFIGLSG-PGVLKVDYLKTMAKD---PIVFAMANPAP--EISPEEA-------------APYVRVMATGRSDYPNQLNNVLCFPGIFRGALDCGARQITEEMKLEVAKAIASAVSDEELSETYIIPDIFN-KEVVKRVRDAVVETAHRTGMA-----------------------------
>UniRef50_Q0STR8(26-377:381) Malate oxidoreductase (NAD) n=7 Tax=Firmicutes RepID=Q0STR8_CLOPS   E=7e-77 s/c=0.83 id=29% cov=50%
----------------------------------------------------------------------------------------------------------------------------------------------------IAVITDGTAVLGLGNIGtLAGYPIVEAKALVYKDLAGVN---AIPLCVDqIGCN----------------------------ELIKTIKNIYSSfSGIHLEDIKAPECFYIEDELKKtlNIPVYHDDQHGTAIAVLGALYNASKVVNKDFSKLKVLILGAGASGIATAKLLLKAGIED----------IILVDKNGALVSGDETLNDPQKEMAK------ITNKELKKGTLEEVIKGR--DVFIGLS-EGNLVTKEMVESM---NEDPIIFALANPTP--EIKPEIAKEA--GARVIATGGPS----------YPNQINNILVFPGLFKGLLEAKATDVTYGVMIAVSKKLASLV-------------------------------------------------------------------
>UniRef50_B9L3E5(489-833:837) NAD-dependent malic enzyme (NAD-ME) n=161 Tax=cellular organisms RepID=B9L3E5_THERP  E=3e-72 s/c=0.80 id=28% cov=61%
----------------------------------------------------------------------------------------------------------------------------------------------------VAIVTDGSAVLGLGDIGPQaALPVMEGKAVLFQSLGGVE---AFPICI--------AERDP---------------DRIVD-IVAAIAPSFGG--INLEDIAAPRCFEIESALKERLdmPVFHDDQHGTAIVVLAALINAFKLRGTPLAEARVVINGAGAAGIATAKLLLVYGVGD----------VILCDRLGAIYREREAGMNR-----YKMEIARLTNKAGVRGDLATAL--VGADAFIGLSS-PNILTPEMIRSMA---PDPIVFALANPDP--EIHPDLALEA--GALVVATG----------RSDFPNQVNNSLAFPGVFRGALDVRARDINDAMKLAAAQAIAELVSPRQLSPQYVIPDSLDLSVPPAVAAAV-ARAAVETGVARlQVDPDDIAARTRELLYE-----------
>UniRef50_C6XH65(50-434:779) Malic enzyme n=1 Tax=Candidatus Liberibacter asiaticus str. psy62 RepID=C6XH65_LIBAP  E=3e-72 s/c=0.71 id=27% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSNGSAVLGLGDIGPlASKPVMEGKAVLFKKFAGIN-------VFDIEINAKDV--------------------DTMVSTIVALEPTFGG--INLEDIKAPECFEVERILSQklKIPFLHDDQHGTAVTVTAATLNGMKLVGKKFSDIKIV--------TLGAGAAALACLNLLVTMGVRRENIWVYDLEGLVYEGRE------KKFDKWKSVYAQKSGPKP---LSETMNNA--DVFLGLS-VAGALDPAILKFMA---EKPLIMVLANPNP--EAMPDEIKK-VRPDAMICTG----------RSDFSNQVNNVLCFPYIFRGALDCGATAITEEMKVAAARAMAVLVRDVPpdvvfdnfakespvFGPNYLIPSPFDPNLISY-IAPAVAKAAEEAGVASSP-IEDYEVYRDS---------------
>UniRef50_B1MWL7(66-385:386) Malic enzyme n=42 Tax=Lactobacillales RepID=B1MWL7_LEUCK   E=6e-69 s/c=0.82 id=32% cov=50%
------------------------------------------------------------------------------------------------------------------------------------------------------VITDGSAVLGLGNIGPaAGLPIVEGKALIYKNFADVN---AIPMALN---------------------------QVSVDEFVNSVKAMAPSfAGIHLEDIAAPRVFEIERRLSEelNIPVYHDDQTGTAIVVLAGLINAAKVVHKKLSELKVIINGVGAAGVATAKILIAAGMT----------KITLIDVHGVVSQNDDRYNSYQRELARKVSQAAG-------ETLDDVI--TGQDVFIGLSDAHVLSGEQV----AKMGARPIIFALANPVP--EILPEEALAA--GAKVVATGS----------SQWPNQVNNVLVFPGLFKGLLASGLKHVDMALQVQIAKALANMMTD-----------------------------------------------------------------
>UniRef50_B2KBV2(62-451:489) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=7 Tax=cellular organisms RepID=B2KBV2_ELUMP  E=1e-68 s/c=0.67 id=27% cov=61%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDSTRVLGDGDCtSPGGLGVMEGKSYLMKLLADVDATS---LCID------------------SKDETGKNSAQKIIDFVLMAQHSFGA--VNLEDISQPNCYKVLDELRKRaiIPVWHDDAQGTATILAAGLINALELAYKKMETVKIVFFGAGAANITACDLIIKMGAD--------PKKIILIDEKGPLNKNRKDLKGSSDFY--KQWAFCLQTNPLNISEVDEAVKGA--DVLIALSKPgPGTIKPKQIKSM---NDKAIVFTCANPVP--EIYPHAAKKA--GAFITATG----------RGDFDNQLNNSVCFPGILKGTLLCGAKTITDNMAVAAARAIADFAKKRGITSDNIVPKMEE-SDIYPTVAAAVAEAAVKEGVASvYLDPKAIYE-------------------
>UniRef50_Q3LR75(103-216:216) Malic enzyme (Fragment) n=2 Tax=Zea mays RepID=Q3LR75_MAIZE   E=2e-41 s/c=1.52 id=37% cov=20%
---------------SGYTLLRDPHHNKGLAFTEKERDAHHSRGLLPPAVLSQELQIKKFMNTLRQYQTPLQRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q16798(42-587:604) NADP-dependent malic enzyme, mitochondrial n=29 Tax=cellular organisms RepID=MAON_HUMAN  E=0 s/c=1.42 id=42% cov=96%
--------RPVPLKKRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGiNCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEMFAQDHPEV---------NSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLEdGKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASyYPEPKDKEAFVRSLVYTPDYDSF-----
>UniRef50_UPI0001B4F654(3-557:559) malate dehydrogenase n=1 Tax=Streptomyces viridochromogenes DSM 40736 RepID=UPI0001B4F654  E=0 s/c=1.24 id=50% cov=98%
-QPKTHRPRTTDSPA--VTTLADPLVNKGTAFSRQEREELGLDGLLPPAVETLDEQAARAYEAFHGYDKPLNRHIYLRQLQDTNEVLFYRLVTEHLEELLPVVYTPTVGEACRRFSEIYRRPRGLFLTWEDRHRFRDILRNRPHgrQDVDVIVVTDGQRILGLGDQGVGGMGIPIGKLSLYTAIGGIHPARTLPILLDVGTDNEDLLGNPRYLGRRDRRLTGAEYDEMIEAFVSAVEAELPGTLLQWEDFATAHAHPILARYRDRLLTFNDDIQGTAAVALGALSTAADVAGTPLTEQRLVILGAGSAAIGVADMIRTAMIDEGLPEDEATARFWILDVDGLLVRSRDELTPQQRMFARDDSEVSDWDG----TGLAEAVRRVEPTALIGLSTAHGAFTEEIVRQMAATCERPVVFPLSNPTSHSEADPADLTRWTDGRALIATGSPFPPLTVDGREVPVAQSNNVYVFPAMGLAVTASRATRVTDRMLVAAARAVARCAVRAADGDDmpvPLLPPLSGMRESAREIALATALAAVEDGVAPQQTKEELRTAIAQAQWTPRY--------
>UniRef50_B0DB82(29-579:579) Malic enzyme n=1 Tax=Laccaria bicolor S238N-H82 RepID=B0DB82_LACBS   E=0 s/c=1.18 id=40% cov=91%
-------------------------------------------GLTPPALNA-SIHAQRCLAQLRSKDKSIEKYIYLSHLKNEDPSIFYKLCLENMVEITPIIYTPTVGDACLQFSHIYRRPEGLYVSIKDKGNIRSVLNNWPKlDEARISVVTDGSRILGLGDLGVNGMGISIGKLSLYIAGAGIRPESTIPICLDLGTNNQKFLDDPFYLGNRHQRVSDKEMEEFMDEFMHEMSRAYPKLMVQFEvsydyilrlqcphlmpnqDFSSDNAFKYLDRYRNKYAVFNDDIQGTGAVVLSGFLNAAKIAsaasGRPLTSHRILFFGAGSAGVGVAIQLQSFFTLQGLSTEEARQQIYLIDSQGLVYNARGRLAEYKKCMlpfslfpswmysSSKPDFSRDDYSGPPMTNILDIIDYVKPTALFGLSTITGAFTPEVIRAMAANNPRPIIFPLSNPVRLSECSFADAVEHTQGAVLFASGSPFPQQQYEGRTLYPGQGNNMYIFPGLGLGAILARVSSVTDSMVKASSLGLADSLTDEERSLGLLYPRIERIREISAHIAKAVIRAAQNADVDrsidlRNVSDSELLRFIHGKMWKP----------
>UniRef50_C7NII8(11-567:609) Malic enzyme n=11 Tax=Bacteria RepID=C7NII8_KYTSD   E=0 s/c=1.16 id=45% cov=96%
------------IAVRGRQVLARPMLNRGSAFTTEQRDALGLRGLIPPAVNSIDDQVRRCYGQFQMQPTNLAKYVYLNTLQDLNEILFHRLVAEHLEEMMPIIYTPTVGEAIQQFSSTFDRQRGIYLSIEDGADAESIATalaaygNGPDDVDIVVVTD-SEGILGIGDQGVGGIRIAIGKSAVYTTAAGIHPLRVLPVVLDVGTDNLALLHDPNYLGLRRERVRGEEYDEFIASFVEAVQERFPTALLHWEDFGATNAHQILERYRDQVCTFNDDIQGTAAIVVASALAACKTKHEQLSEQRVVIHGAGTAGIGIADLMRDIMISEGLDPDEATQRFWGLGSRGLIHTG-GKMRPFQERYARDAAELAEWEADEaGNYSLDEVVRRVQPTILIGTSAQAGAFHEQLVRTMAEGCERPIILPLSNPTSKAEAVPEDLMEWTDGKALIATGSPFKPVVRDEVTHTIAQANNALVFPGMGLGTIAVRATRLTDGMITAAAQAVAEM-TAVGVEGAAILPSMRELRSVSAAVAERVAAAAVEEGVAT-LELENPRAEIEKLMWAPEYPD------
>UniRef50_Q0UYN1(91-556:588) Malic enzyme n=1 Tax=Phaeosphaeria nodorum RepID=Q0UYN1_PHANO   E=1e-170 s/c=1.29 id=42% cov=82%
------------------------------------RRQLGTYGLTPPAVETFEIQSQRCLRLLAMKPTPIEKFQYLVHLKATNPHLFYRVLSQNIKELTPLIYTPTVGEACVRWHEIWTQPEGMYLSFSDRGNLRQILDNWPH-QVDITVLTDGSRILGLGDLGVNGMGIPVGKLALYTACAGIKPDSTLPLTLDLGTNNKALREDPLYMGSRREKVTAAEEKEFLDELMAALTDKWPNIVIQFEDFKNP--FPALERYQNSYAMFNDDVQGTGAVIVGGFINAIKASGVPVRDHRAIFLGAGSAGTGVAMQIVEFF--RGGSDRESAPQFWFVDSNGLVTADR-----------------------------------------------------SILQKMAKLNDRPIIFPLSNPSSKSECTFEEAVVNTNGRCLFASGSPFPSMEWNERTLTPGQGNNMYVFPGIGLGAILSQAVSITQDMIYASAESLSTSLNKQEVADGWLYPDIRRIREVSVVVTRGVIRAAQKNGVDRATElrqlnDASLDAYIVERMYDP----------
>UniRef50_C3MSM1(36-416:432) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=13 Tax=Archaea RepID=C3MSM1_SULIM  E=5e-90 s/c=0.88 id=30% cov=66%
-----------------------------------------------------------------------------------------------------LIYTPGVAEV----------SKAIY---KDPDKSFELTSRWN----TIAVVTDGTRVLGLGNIGPtAAMPVMEGKSLLFKYLGGVD---AIPLPINV-----------------------KSADEFTN-VVKALETSFGG--INLEDIESPKCFYILEKLQSmlNIPVWHDDQQGTAAAILAGLINAMILTNKDPKESKVVFYGAGASNIAAARILAKYGFK--------YENIVMIDSKGPLYADREDvdhlMLHHKWKY-----ELAIKTNKWEAKEIKDAFSGA--DAVVAASTPgPNVIKKEWISLMNKDA---IVFALANPVP--EIWPQDAKEA--GAKIVATG----------RSDFPNQVNNSLIFPAIFRGVLDSRAKAITDEMTIAASEALAKYARDRGINENYIIPRMDEW-EAFYEEAAAVASKAVELGLARvKKSREEFREIAKERI-------------
>UniRef50_O59029(32-409:439) 439aa long hypothetical malate oxidoreductase (NAD) [malic enzyme] n=1 Tax=Pyrococcus horikoshii RepID=O59029_PYRHO  E=2e-84 s/c=0.84 id=30% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDGSRILGLGNIGPlAGLPVMEGKALLFKRFGGVD---AFPIMI-----------------------KEQEPNKFID-IVKAIAPTFGG--INLEDIASPKCFYILERLREEldIPVFHDDQQGTAAVVLAGLLNALKVVGKKISEITLALFGAGAAGFATLRILTEAGVK-----PENVRVVELVNGKPRILTSDLDL---EKLFPYRGWLLKKTNGENIEGGPQEALKDA--DVLISFTRPgPGVIKPQWIEKM---NEDAIVFPLANPVP--EILPEEAKKA--GARIVATG----------RSDYPNQINNLLGFPGIFRGALDVRARTITDSMIIAAAKAIASIV--EEPSEENIIPSPLN-PIVYAREARAVAEEAMKEGVAR----------------------------
>UniRef50_A6TT49(37-394:395) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=8 Tax=Bacteria RepID=A6TT49_ALKMQ  E=2e-83 s/c=0.87 id=29% cov=57%
----------------------------------------------------------------------------------------------------------------------------------------------------VAILTNGTAVLGLGNIGPEaGLPVIEGKALLLKKFGQVD---AMPICLDS-TDSDAII-----------------------KTIQMIAPGFGG--IHLEDIKAPECFYIEEKLREllDIPVYHDDQHGTAIAVLAGLYNALKVTGKSIEDAKIVINGAGASGIATAKLLISAGV----------KHIVLCDLEGTLLEGDTGLNEAQQSIAQ------VTNRQLEKGSLRDIIKN--KDVFIGVSA-GNVVDEAMVRSMNADS---IIFALANPLPEVHPTVAKA----GGARIIATG----------RSDFPNQINNVLVFPGMFKGVLKVRAKDICSEMKIAAAKAIADLVREEELKEDYIVPNVFDKR-VSIGVAKAVMKAAREVGIA-----------------------------
>UniRef50_D1VWF1(35-419:772) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=1 Tax=Prevotella timonensis CRIS 5C-B1 RepID=D1VWF1_9BACT  E=1e-79 s/c=0.78 id=28% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVISNGTAVLGLGDIGAiSGKPVMEGKGLLFKIYGGID-------VFDIELDEK----DP----------------EKFCETVERIAPTFGG--INLEDIKAPECFYIEQRLKKtlDIPVMHDDQHGTAIISAAGLKNALEVAGKDVKTAKLVINGAGAAAISCTNLYMALGIQ--------KENIVMLDSHGVITVDREDLNPQKAAFATNR---------TDIHTLQEAIKGA--DVFVGLS-KGKVLTKDMIRSMA---DRPIVFALANPIP--EISYEEAIE-SRPDVIMSTG----------RSDYPNQINNVIGFPYIFRGALDVHAKAINEEMKMAAVQAIADLAKqpipdvvnevyhinDLVFGPAYFIPKPIDPRLIT-EVSVAVAKAAVKSGVARTP-IEDWGAYRES---------------
>UniRef50_A2BJ64(40-408:465) Malic enzyme n=27 Tax=cellular organisms RepID=A2BJ64_HYPBU   E=3e-79 s/c=0.81 id=30% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSDGTRVLGLGAIGPEGaLPVMEGKALLFKALGGVD---AVPLV---------------------HRARDRE--KFLELLVL-IEPSFGG--INLEDIESPKCFYLLDEARKRlnIPIWHDDQQGTATVTLAGLINAAKLTGRDLRKMRIALIGAGAANTALYRLLKAYGVD--------PKNMVVVDSKGVLHSQREDIEKLKEKNPWKYQIAVETDGGWNQlrgGGIKEALEGAE--AVVAASKPgPGVIKPEWIKLMDKD---PIVFAEANPVP--EIWPWEAKEA--GARVVATG----------RSDFPNQVNNSLAFPSIFRGVLDVRARTITDTMAIAAAEELARFAEEKGLREDYIIPSMEEW-EVYPRVAAATAVRAVEEGVA-----------------------------
>UniRef50_A8L3S1(104-443:464) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=7 Tax=Bacteria RepID=A8L3S1_FRASN  E=1e-77 s/c=0.86 id=29% cov=52%
----------------------------------------------------------------------------------------------------------------------------------------------------VIVVTDGTAVLGLGDIGPaAALPVMEGKAALFKHFGGVD---AVPICLDC-TD--------------------------VEEIVDTVARLAPGfGGVNLEDISAPRCFAIESMLQDRvdIPVFHDDQHGTAIVALAALENAARLTGRTLGDLRAVVSGAGAAGVAVTRILLAAGIGD----------IAVGDSRGMIYPGRDGLTTVKAALA------AETNKAGLRGSINEAL--AGADVYLGLSA--GKVPEEAVATMA---PEAIVFAMANPDP--EIDPEIAHKYAR---IVATG----------RSDYPNQINNVLAFPGVFRGALDVRASRVTEGMKLAAARALADVIADE-LADDNIIPSV-----------------------------------------------------
>UniRef50_B9L3E5(34-411:837) NAD-dependent malic enzyme (NAD-ME) n=161 Tax=cellular organisms RepID=B9L3E5_THERP  E=4e-74 s/c=0.75 id=24% cov=67%
--------------------------------------------------------------------------------------------------MLSLVYTPGVAEACRVISQDEVSS----FDLTGRGNTVAIL-------------TDASDLFGPTRAPVEaALPLLEAKAVLFKTFAGVD---AVPIAVD--------LQDPL----------------AIVEVARSLIPTFGAFCLDH--IRAPHSFTIQDHLEKAapIPVFSNQHHGTAILVLGALKNALEVVGKRLEEVRVVIAGAGLAGIGVARLLTRVGVKD----------LIVCDRAGAIYLGRPYRMNWAKAYLAK-----ETNPERRRGTLAEVLKGA--DVFIGL-ARGNILSPEMVAAMA---PDPIVFALALPTP--EIDPDLARQA--GAAVVATG----------RSDYPNMMDVSLVFPGVFRGLLDSGARNIRLRTLIYAAEALASLVPPEQRGPEHIVPQIFDFRVAPAIAAAVVQAALETKEATREVDPQQVAENTRRYIYE-----------
>UniRef50_A0DE35(319-669:687) Malic enzyme n=3 Tax=Paramecium tetraurelia RepID=A0DE35_PARTE   E=4e-74 s/c=0.80 id=28% cov=57%
----------------------------------------------------------------------------------------------------------------------------------------------------AAIITNGTAILGLGNIGPsAGLPVMEGKSVLFNALGGID---LMPICLK--------EKDP------HKLVR----------IIKCIAPIF--SAINLEDLRAPDCFPIEEEAVQSlhIPLMHDDQHGTAVVSLAAVINYLKLTKKNVKDLKLVIN----------GAGAAGVAIGKLLYGHGIEDIVMCDTSGIIYEGRPqNMNNFKNDLAK------FTNKGKIQGTLADAVKGR--DLFVGVSS-AGALTQDMVRAMNKD---PFILALANPVP--EIMPDEAIEA--GAFIVATG----------RSDFNNQVNNSLAFPGIFRGAIDTRAKEINLEMKIAAAYAIANSIKDSELSTTKILPGALTA-EIPANVARAVAIAAMKTGVA-----------------------------
>UniRef50_B4EEY3(60-440:785) NADP-dependent malic enzyme n=246 Tax=Bacteria RepID=B4EEY3_BURCJ   E=1e-73 s/c=0.73 id=29% cov=58%
------------------------------------------------------------------------------------------------------------------------------------------------------VVTNGTAVLGLGNIGPlASKPVMEGKAVLFKKFAGID-------VFDIELNE----SDP---------------HKLVD-VIAALEPTFGG--INLEDIKAPDCFIVEREARKRmkIPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVA----SGAGAAALACLDLLVDIGLPLE----NITVTDLAGVVYKGRAELMdPDKERFAR----------ETDARTLAEVIDGA--DIFLGLSA-AGVLKQEMVKGMA---ERPLILALANPTP--EILPELALE-VRPDAVLATG----------RTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQHEQsdivataygiqdlsFGPEYLIPKPFDPRLI-VKIAPAVAQAAMDGGVATRP-IEDMEAY------------------
>UniRef50_B3SF22(302-470:470) Malic enzyme (Fragment) n=2 Tax=cellular organisms RepID=B3SF22_TRIAD  E=3e-66 s/c=1.51 id=51% cov=30%
----------------------------GTAFSEQERDLFDLRGFLPPGIEDQEVQVSRARMQLSHMPNDLAKYIYLANLQSQNETIFYRLLMSDPAKYLPIVYDPTVGEACTKFGHIYRASRGLYISIKDKGKVKDILSKWPRKDVKFIVVTDGERILGLGDLGVNGMGIPIGKLALYTAVAGVPPEAQLPIFLDV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9VG31(215-760:763) Malic enzyme n=12 Tax=Diptera RepID=Q9VG31_DROME   E=0 s/c=1.38 id=41% cov=95%
-------------SLSGFTRLLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETDVRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRERRATGDLYDEFIDEFMHACVRRFGqNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAVAGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRDRPkgGLTEHKLHFAQLHEPI---------DTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNNKKFYPGQGNNSYIFPGVALGVLCAGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATvRPEPVNKLAFIKAQMYDLDYPR------
>UniRef50_Q299P1(277-822:825) Malic enzyme n=8 Tax=Arthropoda RepID=Q299P1_DROPS   E=0 s/c=1.38 id=40% cov=95%
---------------SGLTRLHDKRYAKGLAFTHEERQQLGIHGLLPYVVRDDEEQVKHSRILLDRLENDLDKYMYLISLSESNERLFYKVLSSDIAHMMPLVYTPTVGLACQKYSLIYQHAKGMYISIKDKGHVYEVLKNWPETDVRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYVGLRQKRPTGALYDEFIEEFMKGCVRRFGqNCLIQFEDFANANAFRLLSKYRDSYCTFNDDIQGTASVAVAGLLASLKIKKTTLKDNVLLFLGAGEAALGIATLCTMAMKAEGLTDDEAKARIWMVDSRGVIVRDRPkgGLTEHKLQFAQTHVPI---------DTLEEAVRRVRPNVLIGAAAQGGAFTKEILEKMAEINETPIIFALSNPTSKAECTAEEAYTHTQGKCIFASGSPFAPVTYNGRKFYPGQGNNSYIFPGVALGVLCAGMLTIPEEVFLVSAERLAELVSKDDLNRGSLYPPLTSIVNCSIAIAEKIVEYAYKNGLATvYPEPANKVAFIKAQMYDLDYPR------
>UniRef50_B6HKM0(76-627:628) Malic enzyme n=2 Tax=cellular organisms RepID=B6HKM0_PENCW   E=0 s/c=1.27 id=42% cov=96%
---------------DGKSLLQSSQLNKGSAFPDHERSTFKLHSLLPPNIQTLDEQVQRAYQQYQSRPDDLAKNTFLASMKAQNEVLYYKLVQTHLMEMFSVIYTPTEGDAIQNYSRLFRKPEGCFLNINDQDHFAEYLAEFGtADDVDYIVVSDGEEILGIGDQGVGAILISVAKLVITTLCAGIHPSRQLPVVLDCGTDNEELLNDELYLGLRQGRVRGEKYDEFVDRFVHAARKRFPKAYIHFEDFGLQNARRILKRYQEQIPCFNDDIQGTGCVTLAAMLAALQVSRVELEDVRVVIFGSGTAGIGIAGQILDTIATEtGKPKHEASNQIWCIDKPGLLIKSLGDkLTEGQQSFARDDDEWSDSDRD-----LLSVVKKVHPHVLIGTSTKPGAFTEDVIREMAENVERPIIFPLSNPTRLHEAKPADLYHWTDGRALVATGSPFPPVTHNGTQYEIAECNNSTCFPGIGLGAVLSECRLVSKKMLVAAVKALKARSPALKNSDKPLLPDVQDVRDISVDIAAAVILCAVEEGLAQAEDIPtidsDLREWIRIQMWEAEYRPLVYT--
>UniRef50_P40375(1-565:565) NAD-dependent malic enzyme n=3 Tax=Schizosaccharomyces RepID=MAOX_SCHPO  E=0 s/c=1.18 id=40% cov=99%
MPAGTKEQ--IECPLKGVTLLNSPRYNKDTAFTPEERQKFEISSRLPPIVETLQQQVDRCYDQYKAIgDEPLQKNLYLSQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDIDhnDLSYIKQQLSEFGkSDSVEYIIITDSEGILGIGDQGVGGVLISVAKGHLMTLCAGLDPNRFLPIVLDVGTNNETHRKNHQYMGLRKDRVRGEQYDSFLDNVIKAIREVFPEAFIHFEDFGLANAKRILDHYRPDIACFNDDIQGTGAVALAAIIGALHVTKSPLTEQRIMIFGAGTAGVGIANQIVAGMVTDGLSLDKARGNLFMIDRCGLLLERHAKIaTDGQKPFLKKDSDFK--EVPSGDINLESAIALVKPTILLGCSGQPGKFTEKAIREMSKHVERPIIFPISNPTTLMEAKPDQIDKWSDGKALIATGSPLPPLNRNGKKYVISQCNNALLYPALGVACVLSRCKLLSDGMLKAASDALATVPRSLFAADEALLPDLNNAREISRHIVFAVLKQAVSEGMSTVDLPKDdakLKEWIIEREWNPEYKPF-----
>UniRef50_Q291T3(43-572:597) Malic enzyme n=4 Tax=Drosophila RepID=Q291T3_DROPS   E=0 s/c=1.25 id=36% cov=93%
--------------------------NKGLSFTIEERQRLGVHGLWPCSTRNMEEQLYAVGINFQARKDNISKFTYINSLSQRHQRLFYRFLRDYTEAVLPVIYTPTVGEIITSFGLHFKYPDGLYITIFDRGHIRDVLTNWKAKHVRAMCVTDGGRVLGLGDMGANGMGISIGKIALYTALAGVPPDQLLPVCLDVGTDNEELLGDPLYVGARIKRVRGAEYEDFVNEFMEAAVDTFGtDTFIHHEDFATPDAIKFLKKYQYSYCCFNDDVQGTGATGLAGMLNVERVTKRKLQDMVFLFAGAGSAALGIANMLLTALKSRGLTSEEAASKIYLFDQNGLVTCASDKIEAQARKFAKPMDPIKD---------LASAVDHLKPSILLGATGVGSLFSEQVLRSLAKHQERPAVFALSNPTNRTECTAEQAYNFTEGRVLFCSGSPFPPVVFNGKRFTPAQANNCLVFPGIALGAICARARFLPDDVYSEVAVTLAKSTSEERLAAGSLYPAIKEAHSLALDVGVTVCQYLFENGLSnIYPVPKDVCEFVQKTQYRLVYES------
>UniRef50_C0Q8Z2(19-574:576) Mae n=2 Tax=Desulfobacterales RepID=C0Q8Z2_DESAH   E=1e-175 s/c=1.11 id=38% cov=96%
---------------SGSDVLQYKNISKGTAFTEQERQKLHLCGYLPPRVKSLEDQVISSLKVIDEKESDLERFVYIRSLYDRNVTLAHAVIASDISRFLSIIYTPTVGLACQHYSSMFRRANGIHLYPGNIDQAEEILKRYSDRDIRVAVVTDNQGILGIGDQGAGGIAICLGKLMLYTQGAGIAPWHCLPISLDVGTDNKALLDDVTYLGWRKPRLKGEDYLDFIKKFARAFKAVFPKALCQWEDFSKQNAFTIRDVYLNDLISFNDDIQGTGAVALAGILAAMKIKKEKLVDQVFLINGAGAGGIGIAEQIETELIEEGLDGIEARKRIFTMDSKGVVTTDRT-LEPYKEKFAKNPLSLA-WLSSPGDNTLINVIKNEKVTVLIGTSGQPGTFTREVVLAVAANTDQPVILPLSNPTTKAEALPQDVYDWTDGKALVATGSPFAPVTHGGKQIRVGQMNNAFIFPGVGLGILASGALEVLPTFFSAAAHAVAESVTEENLKDGILFPPVDEFRKVSLKVARFVGAESIRGGVSSncaysryqhNNDLERLNTLIEKMCWNPEYLP------
>UniRef50_Q337F1(42-514:532) Malic enzyme n=2 Tax=Eukaryota RepID=Q337F1_ORYSJ   E=1e-172 s/c=1.28 id=43% cov=80%
----------------GTDILHDPWFNKDTAFPMTERDRLGLRGLLPPRVMSFEQQYDRFINSFRSLEHNtrgepdtivaLAKWRILNRLHDRNETLYYRVLIDNIKDFAPIIYTPTVGLVCENYSGLFRRPRGMYFSAKDKGEMMSMIYNWPAEKVDMIVVTDGSRILGLGDLGVQGIGIPIGKLDVYVAAAGINPQKVLPIMLDVGTNNTKLLEDKLYLGLRQPRLEGEEYLSVVDEFMEAVHARWPKAVVQFEDFQMKWAFETLQRYRNRFCMFNDDVQGTAGVALAGLLGAVRAQGRPLSDftkQKIVVVGAGSAGIGVLNMAKQAMLRMpGINRSgEGHNQFWVLDKDGLITKSRKGLDPAVARYARGFGP-EEVQDLHEGASLVEVVRKVKPHVLLGLSGVGGIFNEEVLKAMKEsDSPRPAIFAMSNPTTKAECTPEDVFKYVGDNAVFASGSPFSNVTLgNGRQGYANQANNMYLFPG------------------------------------------------------------------------------------------------
>UniRef50_C6E1I4(33-415:780) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase n=71 Tax=cellular organisms RepID=C6E1I4_GEOSM  E=2e-90 s/c=0.88 id=29% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSNGTAVLGLGNIGAlAGKPVMEGKGVLFKRFADVD-------VFDIELNSE----DP-------------------DEIIRAVQLLEPTfGGINLEDIKAPECFYIEEELKKtmNIPVFHDDQHGTAIISAAGLINALELVGKKIEDVKIVVNGAGASANACANLAISLGLK--------LENLIMCDTKGVIYKGRvEGMNKYKERFAAD----------TPLRTLEEA--AVGADVMYGLSAK-GAITPEMVRSMAAN---PIIFAMANPDP--EITPEEAH-AVRGDVLIATG----------RSDYPNQVNNVLGFPFIFRGALDVRATTINEEMKKAAVFALAELAREEcpdsvcraygdvkfSFGRDYIIPKPFDPRAL-LRVAPAIAKAAMETGVARQP-IADMNKYVE----------------
>UniRef50_Q5C370(1-264:264) Malic enzyme (Fragment) n=1 Tax=Schistosoma japonicum RepID=Q5C370_SCHJA  E=3e-81 s/c=1.16 id=34% cov=46%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGEEYISFMDEVVESLSAHYgPNVCLHFADLKNSNAFQLLERYRPNYITFNDDIQGSAVVIVSGLLTASRITKKKISQNTYLFYGSGGASIGIARLLVQAIIEEGFTEDEAKSRIFMMDSRGLLVTNRE-LTKAKSEFARSDYP--------QIDSLLEAIRLIRPSVLIGSSAQSGAFSRDILRELSAISRIPIIFVLSNSSNLGECTAQMAYKATEWRCIFVSGSPSEPVLTPdDRILKPSQGNNCYVFPSLINALSLAVIRPLTNKLLL-----------------------------------------------------------------------------
>UniRef50_O30807(48-432:770) NAD-dependent malic enzyme n=470 Tax=root RepID=MAO1_RHIME   E=1e-73 s/c=0.73 id=28% cov=59%
----------------------------------------------------------------------------------------------------------------------------------------------------VAVVSNGTAVLGLGNIGPlASKPVMEGKAVLFKKFAGID-------VFDIEIDAPTV-------------------DRMVD-VISALEPTFGG--INLEDIKAPECFEVERRLREKmeIPVFHDDQHGTAIIVAAAVLNGLELAGKDIAEAKIVAS--------GAGAAALACLNLLVTLGARRENIWVHDIEGLVYKGREALMDEWK---------AVYAQESDNRVLADSIGGA--DVFLGLSA-AGVLKPELLARMA---EKPLIMALANPTP--EIMPEVA-RAARPDAMICTG----------RSDFPNQVNNVLCFPHIFRGALDCGARTINEEMKMAAVRAIAGLAREEPsdvaaraysgetpvFGPDYLIPSPFDQRLI-LRIAPAVAKAAAESGVATRP-IQDFDAYLDK---------------
>UniRef50_D1B9U0(58-407:414) Malate dehydrogenase (Oxaloacetate-decarboxylating) n=1 Tax=Thermanaerovibrio acidaminovorans DSM 6589 RepID=D1B9U0_THEAS  E=2e-73 s/c=0.80 id=27% cov=60%
---------------------------------------------------------------------------------------------------------------------------------------------------RVAVVTDGSAVLGLGDVGPaAALPVMEGKCLLFKLFGDIN---AFPMCLDT--------NDP-------------------DEVVHCVRLMAPTlGGVNVEDISSPNTFTVVRKLRStlDIPVLCDDQHGTSVLMLAALKNSLKLVEKRLEDVRIVIIGAGAAGVATVELLLAAGAR----------NVVCLNSSGVLGEENPRMDHIQAELAQR------TNPEGIRGGIAEALKGA--DVMIGLS-RGGLVSPNHVASMSKGA---VVFAMALPDP--EISYEEAVSAG------------AAVVATGSVEHPNPLLNLQAFPGIMRGALDVRATAISDSMLIAAADALASVTEDHELSPQNVLADPF-CDETAPRVAEAVAQAAIREGLASNILPPG---QVYNETWQRIY--------
>UniRef50_C7DHL6(30-413:429) Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) n=1 Tax=Candidatus Micrarchaeum acidiphilum ARMAN-2 RepID=C7DHL6_9EURY  E=8e-72 s/c=0.71 id=27% cov=60%
----------------------------------------------------------------------------------------------------------------------------------------------------IAIVSDGTRILGLGNIGPEaGLPVMEGKALLFKKFGAVD---AIPLCI--GTTDEQE----------------------IIKFVKNIAPTFGAVNI--EDIESPKCFDIVDSLSDSlgIPVFHDDQHGTSVVITAGLINALKLAGKTIKNINIVINGAGAAGLGEVRMLNYMGV----------KNILVLDKAGIIYEGRqENMNKYKDEIAK------ATNPSKKSGTLEDAVKNA--DVLIGVSS-AGSFNKNLISLMG---DKPIVFALANPVP--EIGYEDAKAAG------------AFVAATGQSGKPNQVNNVLSFPAIMRGILDARVIKIKYDLLYYAAKALSQAAG-KNLAVEHILPDPSnrkEMRRVVENVAVAIGEAALKSNntMVKEIDPSAMRRSIAERL-------------
>UniRef50_B5Y841(24-396:399) Malate oxidoreductase n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y841_COPPD  E=8e-65 s/c=0.67 id=27% cov=59%
------------------------------------------------------------------------------------------------------------------------------------------------------VISNGTRILGLGNIGPEaGLPVMEGKAVLYKYYAGID---AIPLCIRAET------------------------EEAILAFLSAIEPSLGG--INLEDIKQPDAFNVLTEARKflRIPIIHDDMEGTGIIMLAAVLASSSMAGLKLESEKIVLLGAGSANMG-------FLQLLDELLLGNIGNVIVVDRD-LVYNSENSQQ-------HWMGNILSKTNKLGSSNLEEALKGA--SFLIAASRPgPGVFPLEYLRNMKKPNT---VLSLANPVP--EVSREEACAM--GVTIYGSG----------RSDDPNQVNNSLIFPGLMLGLLVTQQQYNT-----AVGIEVAKALSELAMKKQRIVPQMDS--EVHQFVARTVVEH-FSKKCASKENASMWAEELNWRM-------------
>UniRef50_P54572(111-398:439) Probable NAD-dependent malic enzyme 1 n=5 Tax=Bacteria RepID=MAO1_BACSU  E=1e-51 s/c=0.72 id=31% cov=50%
------------------------------------------------------------------------------------------------------VYTPGVADVCR---LIEKEPE--------KASIYTTISN------SVAIVTDGTAILGLGNIGsVAGMPVMEGKAALFDQLAGI---SGIPILLDT--------SDP-------------------EEIIKTVKHISPGfSGILLEDIGSPHCFEIEDRLKEelNIPVMHDDQHGTAVVTLAAAISACRSAGVDLKEAKVGQIGLGAAGVAICRMFMAYGVNA----------VYGTD---------------KSESAMNRLEQYGGQAVSSIEELMETC-----DIVIATTGVPGLIKPAFVRSGQ------VILALSNP--KPEIEPEAALQAG------------AAYAADGRS-----VNNVLGFPGIFRGALNAKSTEINHDML------------------------------------------------------------------------------
