Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	I	I	S	T	K	Y	L	L	Q	D	A	Q	A	N	G	Y	A	V	P	A	F	N	I	H	N	A	E	T	I	Q	A	I	L	E	V	C	S	E	M	R	S	P	V	I	L	A	G	T	P	G	T	F	K	H	I	A	L	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	I	Y	A	L	C	S	A	Y	S	T	T	Y	N	M	P	L	A	L	H	L	D	H	H	E	S	L	D	D	I	R	R	K	V	H	A	G	V	R	S	A	M	I	D	G	S	H	F	P	F	A	E	N	V	K	L	V	K	S	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	D	F	C	H	S	Q	D	C	S	V	E	A	E	L	G	R	L	G	G	V	E	D	D	M	S	V	D	A	E	S	A	F	L	T	D	P	Q	E	A	K	R	F	V	E	L	T	G	V	D	S	L	A	V	A	I	G	T	A	H
Secondary structure
SS confidence
Disorder																				?		?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	L	Y	S	K	T	P	K	I	D	F	Q	R	L	A	E	I	R	E	V	V	D	V	P	L	V	L	H	G	A	S	D	V	P	D	E	F	V	R	R	T	I	E	L	G	V	T	K	V	N	V	A	T	E	L	K	I	A	F	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Sequence		G	A	V	K	A	W	F	A	E	N	P	Q	G	N	D	P	R	Y	Y	M	R	V	G	M	D	A	M	K	E	V	V	R	N	K	I	N	V	C	G	S	A	N	R	I	S	A
Secondary structure
SS confidence
Disorder												?																															?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1gvf chain A Region: 2 - 285 Aligned: 273 Modelled: 284 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class II FBP aldolase Phyre2 PDB 3q94 chain B Region: 2 - 284 Aligned: 273 Modelled: 273 Confidence: 100.0% Identity: 40% PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor' Phyre2 PDB 1rvg chain A Region: 3 - 284 Aligned: 275 Modelled: 282 Confidence: 100.0% Identity: 43% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class II FBP aldolase Phyre2 PDB 3c52 chain B Region: 3 - 284 Aligned: 270 Modelled: 282 Confidence: 100.0% Identity: 41% PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor Phyre2 PDB 1dos chain A Region: 1 - 284 Aligned: 284 Modelled: 284 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class II FBP aldolase Phyre2 PDB 3elf chain A Region: 2 - 284 Aligned: 270 Modelled: 283 Confidence: 100.0% Identity: 26% PDB header:lyase Chain: A: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase Phyre2 PDB 3qm3 chain C Region: 1 - 283 Aligned: 280 Modelled: 278 Confidence: 100.0% Identity: 26% PDB header:lyase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni Phyre2 PDB 2isw chain B Region: 2 - 285 Aligned: 256 Modelled: 267 Confidence: 100.0% Identity: 44% PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate Phyre2 PDB 3pm6 chain B Region: 6 - 285 Aligned: 248 Modelled: 264 Confidence: 100.0% Identity: 32% PDB header:lyase Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase; PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr Phyre2 PDB 2fiq chain A domain 1 Region: 7 - 264 Aligned: 251 Modelled: 257 Confidence: 99.4% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: GatZ-like Phyre2 PDB 2qjh chain H Region: 16 - 267 Aligned: 200 Modelled: 220 Confidence: 99.1% Identity: 19% PDB header:lyase Chain: H: PDB Molecule:putative aldolase mj0400; PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate Phyre2 PDB 2ze3 chain A Region: 1 - 249 Aligned: 226 Modelled: 246 Confidence: 98.7% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus Phyre2 PDB 3gr7 chain A Region: 16 - 235 Aligned: 195 Modelled: 196 Confidence: 98.6% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form Phyre2 PDB 1thf chain D Region: 34 - 235 Aligned: 193 Modelled: 202 Confidence: 98.6% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Histidine biosynthesis enzymes Phyre2 PDB 2c3z chain A Region: 2 - 237 Aligned: 202 Modelled: 217 Confidence: 98.6% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus Phyre2 PDB 1ps9 chain A domain 1 Region: 28 - 235 Aligned: 183 Modelled: 190 Confidence: 98.5% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: FMN-linked oxidoreductases Family: FMN-linked oxidoreductases Phyre2 PDB 2h90 chain A Region: 28 - 235 Aligned: 181 Modelled: 181 Confidence: 98.4% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin Phyre2 PDB 3hf3 chain A Region: 20 - 235 Aligned: 191 Modelled: 192 Confidence: 98.4% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 Phyre2 PDB 1j5t chain A Region: 35 - 246 Aligned: 179 Modelled: 193 Confidence: 98.3% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 3gnd chain C Region: 73 - 262 Aligned: 161 Modelled: 174 Confidence: 98.3% Identity: 20% PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate Phyre2 1 d1gvfa_ 2 c3q94B_ 3 d1rvga_ 4 c3c52B_ 5 d1dosa_ 6 c3elfA_ 7 c3qm3C_ 8 c2iswB_ 9 c3pm6B_ 10 d2fiqa1 11 c2qjhH_ 12 c2ze3A_ 13 c3gr7A_ 14 d1thfd_ 15 c2c3zA_ 16 d1ps9a1 17 c2h90A_ 18 c3hf3A_ 19 d1j5ta_ 20 c3gndC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499