Phyre 2 Results for P77173

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | P77173
Date | Thu Jan 5 12:25:58 GMT 2012
Unique Job ID | e842081890ccb440

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1f46a_
Top template information
Fold:TBP-like Superfamily:Cell-division protein ZipA, C-terminal domain Family:Cell-division protein ZipA, C-terminal domain
Confidence and coverage
Confidence: | 100.0% | Coverage: | 42%
138 residues ( 42% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Warning: 55% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | M | Q | D | L | R | L | I | L | I | I | V | G | A | I | A | I | I | A | L | L | V | H | G | F | W | T | S | R | K | E | R | S | S | M | F | R | D | R | P | L | K | R | M | K | S | K | R | D | D | D | S | Y | D | E | D | V | E | D | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | E | G | V | G | E | V | R | V | H | R | V | N | H | A | P | A | N | A | Q | E | H | E | A | A | R | P | S | P | Q | H | Q | Y | Q | P | P | Y | A | S | A | Q | P | R | Q | P | V | Q | Q | P | P | E | A | Q | V | P | P | Q | H | A | P | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | P | A | Q | P | V | Q | Q | P | A | Y | Q | P | Q | P | E | Q | P | L | Q | Q | P | V | S | P | Q | V | A | P | A | P | Q | P | V | H | S | A | P | Q | P | A | Q | Q | A | F | Q | P | A | E | P | V | A | A | P | Q | P | E | P | V | A | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | P | A | P | V | M | D | K | P | K | R | K | E | A | V | I | I | M | N | V | A | A | H | H | G | S | E | L | N | G | E | L | L | L | N | S | I | Q | Q | A | G | F | I | F | G | D | M | N | I | Y | H | R | H | L | S | P | D | G | S | G | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | A | L | F | S | L | A | N | M | V | K | P | G | T | F | D | P | E | M | K | D | F | T | T | P | G | V | T | I | F | M | Q | V | P | S | Y | G | D | E | L | Q | N | F | K | L | M | L | Q | S | A | Q | H | I | A | D | E | V | G | G | V | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | .
Sequence |  | L | D | D | Q | R | R | M | M | T | P | Q | K | L | R | E | Y | Q | D | I | I | R | E | V | K | D | A | N | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1f46a_ |

### PDB 1f46 chain A

Region: 191 - 328
Aligned: 138
Modelled: 138
Confidence: 100.0%
Identity: 99%
Fold: TBP-like
Superfamily: Cell-division protein ZipA, C-terminal domain
Family: Cell-division protein ZipA, C-terminal domain

Phyre2
2 |
| c1qmiC_ |

### PDB 1qmi chain C

Region: 212 - 292
Aligned: 75
Modelled: 81
Confidence: 79.0%
Identity: 13%
PDB header:rna 3'-terminal phosphate cyclase
Chain: C: PDB Molecule:rna 3'-terminal phosphate cyclase;
PDBTitle: crystal structure of rna 3'-terminal phosphate cyclase, an2 ubiquitous enzyme with unusual topology

Phyre2
3 |
| c2kncA_ |

### PDB 2knc chain A

Region: 7 - 39
Aligned: 33
Modelled: 33
Confidence: 75.4%
Identity: 18%
PDB header:cell adhesion
Chain: A: PDB Molecule:integrin alpha-iib;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2
4 |
| c3sokB_ |

### PDB 3sok chain B

Region: 4 - 34
Aligned: 31
Modelled: 31
Confidence: 55.5%
Identity: 19%
PDB header:cell adhesion
Chain: B: PDB Molecule:fimbrial protein;
PDBTitle: dichelobacter nodosus pilin fima

Phyre2
5 |
| d2pila_ |

### PDB 2pil chain A

Region: 4 - 34
Aligned: 31
Modelled: 31
Confidence: 48.9%
Identity: 32%
Fold: Pili subunits
Superfamily: Pili subunits
Family: Pilin

Phyre2
6 |
| c2kncB_ |

### PDB 2knc chain B

Region: 5 - 27
Aligned: 23
Modelled: 23
Confidence: 45.6%
Identity: 35%
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex

Phyre2
7 |
| d2axtj1 |

### PDB 2axt chain J domain 1

Region: 7 - 24
Aligned: 18
Modelled: 18
Confidence: 45.0%
Identity: 33%
Fold: Single transmembrane helix
Superfamily: Photosystem II reaction center protein J, PsbJ
Family: PsbJ-like

Phyre2
8 |
| c1afoB_ |

### PDB 1afo chain B

Region: 3 - 30
Aligned: 28
Modelled: 28
Confidence: 43.6%
Identity: 36%
PDB header:integral membrane protein
Chain: B: PDB Molecule:glycophorin a;
PDBTitle: dimeric transmembrane domain of human glycophorin a, nmr,2 20 structures

Phyre2
9 |
| c2k21A_ |

### PDB 2k21 chain A

Region: 7 - 33
Aligned: 27
Modelled: 27
Confidence: 41.0%
Identity: 15%
PDB header:membrane protein
Chain: A: PDB Molecule:potassium voltage-gated channel subfamily e
PDBTitle: nmr structure of human kcne1 in lmpg micelles at ph 6.0 and2 40 degree c

Phyre2
10 |
| c2jwaA_ |

### PDB 2jwa chain A

Region: 7 - 33
Aligned: 27
Modelled: 27
Confidence: 40.6%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-2;
PDBTitle: erbb2 transmembrane segment dimer spatial structure

Phyre2
11 |
| d1oqwa_ |

### PDB 1oqw chain A

Region: 4 - 34
Aligned: 31
Modelled: 31
Confidence: 39.3%
Identity: 29%
Fold: Pili subunits
Superfamily: Pili subunits
Family: Pilin

Phyre2
12 |
| c3pqvD_ |

### PDB 3pqv chain D

Region: 212 - 300
Aligned: 84
Modelled: 89
Confidence: 38.3%
Identity: 17%
PDB header:unknown function
Chain: D: PDB Molecule:rcl1 protein;
PDBTitle: cyclase homolog

Phyre2
13 |
| c2l9uA_ |

### PDB 2l9u chain A

Region: 3 - 31
Aligned: 29
Modelled: 29
Confidence: 38.1%
Identity: 24%
PDB header:membrane protein
Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-3;
PDBTitle: spatial structure of dimeric erbb3 transmembrane domain

Phyre2
14 |
| c2it3B_ |

### PDB 2it3 chain B

Region: 195 - 224
Aligned: 28
Modelled: 30
Confidence: 33.2%
Identity: 25%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:upf0130 protein ph1069;
PDBTitle: structure of ph1069 protein from pyrococcus horikoshii

Phyre2
15 |
| c2dvkA_ |

### PDB 2dvk chain A

Region: 195 - 223
Aligned: 27
Modelled: 29
Confidence: 32.2%
Identity: 19%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:upf0130 protein ape0816;
PDBTitle: crystal structure of hypothetical protein from aeropyrum pernix

Phyre2
16 |
| d2o02a1 |

### PDB 2o02 chain A domain 1

Region: 282 - 325
Aligned: 43
Modelled: 44
Confidence: 31.3%
Identity: 14%
Fold: alpha-alpha superhelix
Superfamily: 14-3-3 protein
Family: 14-3-3 protein

Phyre2
17 |
| c2qg3B_ |

### PDB 2qg3 chain B

Region: 195 - 224
Aligned: 28
Modelled: 30
Confidence: 31.0%
Identity: 32%
PDB header:unknown function
Chain: B: PDB Molecule:upf0130 protein af_2059;
PDBTitle: crystal structure of a tyw3 methyltransferase-like protein (af_2059)2 from archaeoglobus fulgidus dsm 4304 at 1.95 a resolution

Phyre2
18 |
| d1fftb2 |

### PDB 1fft chain B domain 2

Region: 1 - 35
Aligned: 35
Modelled: 35
Confidence: 30.7%
Identity: 20%
Fold: Transmembrane helix hairpin
Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region
Family: Cytochrome c oxidase subunit II-like, transmembrane region

Phyre2
19 |
| c2jp3A_ |

### PDB 2jp3 chain A

Region: 8 - 42
Aligned: 35
Modelled: 35
Confidence: 30.3%
Identity: 20%
PDB header:transcription
Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4;
PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles

Phyre2
20 |
| c2c1nA_ |

### PDB 2c1n chain A

Region: 282 - 325
Aligned: 43
Modelled: 44
Confidence: 28.5%
Identity: 14%
PDB header:signaling protein
Chain: A: PDB Molecule:14-3-3 protein zeta/delta;
PDBTitle: molecular basis for the recognition of phosphorylated and2 phosphoacetylated histone h3 by 14-3-3

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1f46a_ |
|  | 100.0 | 99 | Fold:TBP-like Superfamily:Cell-division protein ZipA, C-terminal domain Family:Cell-division protein ZipA, C-terminal domain
2 | c1qmiC_ |
|  | 79.0 | 13 | PDB header:rna 3'-terminal phosphate cyclase Chain: C: PDB Molecule:rna 3'-terminal phosphate cyclase; PDBTitle: crystal structure of rna 3'-terminal phosphate cyclase, an2 ubiquitous enzyme with unusual topology
3 | c2kncA_ |
|  | 75.4 | 18 | PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
4 | c3sokB_ |
|  | 55.5 | 19 | PDB header:cell adhesion Chain: B: PDB Molecule:fimbrial protein; PDBTitle: dichelobacter nodosus pilin fima
5 | d2pila_ |
|  | 48.9 | 32 | Fold:Pili subunits Superfamily:Pili subunits Family:Pilin
6 | c2kncB_ |
|  | 45.6 | 35 | PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
7 | d2axtj1 |
|  | 45.0 | 33 | Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein J, PsbJ Family:PsbJ-like
8 | c1afoB_ |
|  | 43.6 | 36 | PDB header:integral membrane protein Chain: B: PDB Molecule:glycophorin a; PDBTitle: dimeric transmembrane domain of human glycophorin a, nmr,2 20 structures
9 | c2k21A_ |
|  | 41.0 | 15 | PDB header:membrane protein Chain: A: PDB Molecule:potassium voltage-gated channel subfamily e PDBTitle: nmr structure of human kcne1 in lmpg micelles at ph 6.0 and2 40 degree c
10 | c2jwaA_ |
|  | 40.6 | 26 | PDB header:transferase Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-2; PDBTitle: erbb2 transmembrane segment dimer spatial structure
11 | d1oqwa_ |
|  | 39.3 | 29 | Fold:Pili subunits Superfamily:Pili subunits Family:Pilin
12 | c3pqvD_ |
|  | 38.3 | 17 | PDB header:unknown function Chain: D: PDB Molecule:rcl1 protein; PDBTitle: cyclase homolog
13 | c2l9uA_ |
|  | 38.1 | 24 | PDB header:membrane protein Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-3; PDBTitle: spatial structure of dimeric erbb3 transmembrane domain
14 | c2it3B_ |
|  | 33.2 | 25 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:upf0130 protein ph1069; PDBTitle: structure of ph1069 protein from pyrococcus horikoshii
15 | c2dvkA_ |
|  | 32.2 | 19 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0130 protein ape0816; PDBTitle: crystal structure of hypothetical protein from aeropyrum pernix
16 | d2o02a1 |
|  | 31.3 | 14 | Fold:alpha-alpha superhelix Superfamily:14-3-3 protein Family:14-3-3 protein
17 | c2qg3B_ |
|  | 31.0 | 32 | PDB header:unknown function Chain: B: PDB Molecule:upf0130 protein af_2059; PDBTitle: crystal structure of a tyw3 methyltransferase-like protein (af_2059)2 from archaeoglobus fulgidus dsm 4304 at 1.95 a resolution
18 | d1fftb2 |
|  | 30.7 | 20 | Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region
19 | c2jp3A_ |
|  | 30.3 | 20 | PDB header:transcription Chain: A: PDB Molecule:fxyd domain-containing ion transport regulator 4; PDBTitle: solution structure of the human fxyd4 (chif) protein in sds2 micelles
20 | c2c1nA_ |
|  | 28.5 | 14 | PDB header:signaling protein Chain: A: PDB Molecule:14-3-3 protein zeta/delta; PDBTitle: molecular basis for the recognition of phosphorylated and2 phosphoacetylated histone h3 by 14-3-3
21 | d1tlja_ |
| not modelled | 26.6 | 25 | Fold:SSo0622-like Superfamily:SSo0622-like Family:SSo0622-like
22 | c1tljA_ |
| not modelled | 26.6 | 25 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical upf0130 protein sso0622; PDBTitle: crystal structure of conserved protein of unknown function2 sso0622 from sulfolobus solfataricus
23 | d1q1la_ |
| not modelled | 25.0 | 15 | Fold:Chorismate synthase, AroC Superfamily:Chorismate synthase, AroC Family:Chorismate synthase, AroC
24 | d1hywa_ |
| not modelled | 24.0 | 21 | Fold:gpW/XkdW-like Superfamily:Head-to-tail joining protein W, gpW Family:Head-to-tail joining protein W, gpW
25 | c1ztbA_ |
| not modelled | 22.9 | 16 | PDB header:ligase Chain: A: PDB Molecule:chorismate synthase; PDBTitle: crystal structure of chorismate synthase from mycobacterium2 tuberculosis
26 | d1xrda1 |
| not modelled | 22.8 | 30 | Fold:Light-harvesting complex subunits Superfamily:Light-harvesting complex subunits Family:Light-harvesting complex subunits
27 | d1wfya_ |
| not modelled | 22.5 | 12 | Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:Ras-binding domain, RBD
28 | c2jo1A_ |
| not modelled | 22.1 | 33 | PDB header:hydrolase regulator Chain: A: PDB Molecule:phospholemman; PDBTitle: structure of the na,k-atpase regulatory protein fxyd1 in2 micelles
29 | c2k1aA_ |
| not modelled | 21.9 | 14 | PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: bicelle-embedded integrin alpha(iib) transmembrane segment
30 | d1ijda_ |
| not modelled | 21.6 | 60 | Fold:Light-harvesting complex subunits Superfamily:Light-harvesting complex subunits Family:Light-harvesting complex subunits
31 | c2x2oA_ |
| not modelled | 21.1 | 15 | PDB header:flavoprotein Chain: A: PDB Molecule:nrdi protein; PDBTitle: the flavoprotein nrdi from bacillus cereus with the2 initially oxidized fmn cofactor in an intermediate3 radiation reduced state
32 | d1o9da_ |
| not modelled | 18.4 | 7 | Fold:alpha-alpha superhelix Superfamily:14-3-3 protein Family:14-3-3 protein
33 | d1mx3a2 |
| not modelled | 17.9 | 19 | Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain
34 | d1nkza_ |
| not modelled | 17.5 | 43 | Fold:Light-harvesting complex subunits Superfamily:Light-harvesting complex subunits Family:Light-harvesting complex subunits
35 | c2mltB_ |
| not modelled | 17.2 | 33 | PDB header:toxin (hemolytic polypeptide) Chain: B: PDB Molecule:melittin; PDBTitle: melittin
36 | c2npmB_ |
| not modelled | 16.9 | 7 | PDB header:protein binding Chain: B: PDB Molecule:14-3-3 domain containing protein; PDBTitle: crystal structure of cryptosporidium parvum 14-3-3 protein2 in complex with peptide
37 | c2mltA_ |
| not modelled | 16.9 | 33 | PDB header:toxin (hemolytic polypeptide) Chain: A: PDB Molecule:melittin; PDBTitle: melittin
38 | d1c99a_ |
| not modelled | 16.0 | 26 | Fold:Transmembrane helix hairpin Superfamily:F1F0 ATP synthase subunit C Family:F1F0 ATP synthase subunit C
39 | d1qw1a1 |
| not modelled | 16.0 | 16 | Fold:SH3-like barrel Superfamily:C-terminal domain of transcriptional repressors Family:FeoA-like
40 | d1qxoa_ |
| not modelled | 15.9 | 14 | Fold:Chorismate synthase, AroC Superfamily:Chorismate synthase, AroC Family:Chorismate synthase, AroC
41 | c1qcrD_ |
| not modelled | 15.1 | 25 | PDB header: PDB COMPND:
42 | c1fftG_ |
| not modelled | 14.2 | 18 | PDB header:oxidoreductase Chain: G: PDB Molecule:ubiquinol oxidase; PDBTitle: the structure of ubiquinol oxidase from escherichia coli
43 | c2kluA_ |
| not modelled | 14.1 | 32 | PDB header:immune system, membrane protein Chain: A: PDB Molecule:t-cell surface glycoprotein cd4; PDBTitle: nmr structure of the transmembrane and cytoplasmic domains2 of human cd4
44 | c3u5eL_ |
| not modelled | 14.0 | 14 | PDB header:ribosome Chain: L: PDB Molecule:60s ribosomal protein l13-a; PDBTitle: the structure of the eukaryotic ribosome at 3.0 resolution
45 | c3e6yB_ |
| not modelled | 13.5 | 9 | PDB header:signaling protein Chain: B: PDB Molecule:14-3-3-like protein c; PDBTitle: structure of 14-3-3 in complex with the differentiation-inducing agent2 cotylenin a
46 | c2kxhB_ |
| not modelled | 13.5 | 50 | PDB header:protein binding Chain: B: PDB Molecule:peptide of far upstream element-binding protein 1; PDBTitle: solution structure of the first two rrm domains of fir in the complex2 with fbp nbox peptide
47 | d2o8pa1 |
| not modelled | 13.1 | 17 | Fold:alpha-alpha superhelix Superfamily:14-3-3 protein Family:14-3-3 protein
48 | c4a1bO_ |
| not modelled | 12.9 | 22 | PDB header:ribosome Chain: O: PDB Molecule:rpl28; PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 26s rrna and3 proteins of molecule 3.
49 | c2k9yA_ |
| not modelled | 12.8 | 23 | PDB header:transferase Chain: A: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0
50 | c2k9yB_ |
| not modelled | 12.8 | 23 | PDB header:transferase Chain: B: PDB Molecule:ephrin type-a receptor 2; PDBTitle: epha2 dimeric structure in the lipidic bicelle at ph 5.0
51 | c2hg5D_ |
| not modelled | 12.2 | 4 | PDB header:membrane protein Chain: D: PDB Molecule:kcsa channel; PDBTitle: cs+ complex of a k channel with an amide to ester substitution in the2 selectivity filter
52 | c2zxeG_ |
| not modelled | 12.2 | 20 | PDB header:hydrolase/transport protein Chain: G: PDB Molecule:phospholemman-like protein; PDBTitle: crystal structure of the sodium - potassium pump in the e2.2k+.pi2 state
53 | d1ydla1 |
| not modelled | 11.9 | 20 | Fold:TFB5-like Superfamily:TFB5-like Family:TFB5-like
54 | c3bwwA_ |
| not modelled | 11.8 | 23 | PDB header:metal binding protein Chain: A: PDB Molecule:protein of unknown function duf692/cog3220; PDBTitle: crystal structure of a duf692 family protein (hs_1138) from2 haemophilus somnus 129pt at 2.20 a resolution
55 | c3cs5B_ |
| not modelled | 11.6 | 27 | PDB header:photosynthesis Chain: B: PDB Molecule:phycobilisome degradation protein nbla; PDBTitle: nbla protein from synechococcus elongatus pcc 7942
56 | c2j7aC_ |
| not modelled | 11.2 | 20 | PDB header:oxidoreductase Chain: C: PDB Molecule:cytochrome c quinol dehydrogenase nrfh; PDBTitle: crystal structure of cytochrome c nitrite reductase nrfha2 complex from desulfovibrio vulgaris
57 | d2nlya1 |
| not modelled | 10.7 | 12 | Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:Divergent polysaccharide deacetylase
58 | c3dgpB_ |
| not modelled | 10.5 | 21 | PDB header:transcription Chain: B: PDB Molecule:rna polymerase ii transcription factor b subunit 5; PDBTitle: crystal structure of the complex between tfb5 and the c-terminal2 domain of tfb2
59 | d1ul7a_ |
| not modelled | 10.5 | 3 | Fold:TBP-like Superfamily:KA1-like Family:Kinase associated domain 1, KA1
60 | c2pcrA_ |
| not modelled | 10.5 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:inositol-1-monophosphatase; PDBTitle: crystal structure of myo-inositol-1(or 4)-monophosphatase (aq_1983)2 from aquifex aeolicus vf5
61 | d1v54i_ |
| not modelled | 9.0 | 13 | Fold:Single transmembrane helix Superfamily:Mitochondrial cytochrome c oxidase subunit VIc Family:Mitochondrial cytochrome c oxidase subunit VIc
62 | c3mk7F_ |
| not modelled | 9.0 | 19 | PDB header:oxidoreductase Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p; PDBTitle: the structure of cbb3 cytochrome oxidase
63 | d2bkra1 |
| not modelled | 8.8 | 6 | Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Adenain-like
64 | d1rlja_ |
| not modelled | 8.8 | 15 | Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavoprotein NrdI
65 | c3n23E_ |
| not modelled | 8.5 | 27 | PDB header:hydrolase Chain: E: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the high affinity complex between ouabain and the2 e2p form of the sodium-potassium pump
66 | c2latA_ |
| not modelled | 8.2 | 12 | PDB header:membrane protein Chain: A: PDB Molecule:dolichyl-diphosphooligosaccharide--protein PDBTitle: solution structure of a human minimembrane protein ost4
67 | d1xzpa3 |
| not modelled | 8.1 | 20 | Fold:Folate-binding domain Superfamily:Folate-binding domain Family:TrmE formyl-THF-binding domain
68 | c1xzqB_ |
| not modelled | 8.1 | 20 | PDB header:hydrolase Chain: B: PDB Molecule:probable trna modification gtpase trme; PDBTitle: structure of the gtp-binding protein trme from thermotoga2 maritima complexed with 5-formyl-thf
69 | c2q74B_ |
| not modelled | 7.8 | 21 | PDB header:hydrolase Chain: B: PDB Molecule:inositol-1-monophosphatase; PDBTitle: mycobacterium tuberculosis suhb
70 | c2g2bA_ |
| not modelled | 7.7 | 7 | PDB header:immune system Chain: A: PDB Molecule:allograft inflammatory factor 1; PDBTitle: nmr structure of the human allograft inflammatory factor 1
71 | c2i7gA_ |
| not modelled | 7.6 | 31 | PDB header:oxidoreductase Chain: A: PDB Molecule:monooxygenase; PDBTitle: crystal structure of monooxygenase from agrobacterium tumefaciens
72 | c3otbB_ |
| not modelled | 7.4 | 23 | PDB header:transferase Chain: B: PDB Molecule:trna(his) guanylyltransferase; PDBTitle: crystal structure of human trnahis guanylyltransferase (thg1) - dgtp2 complex
73 | c2qflA_ |
| not modelled | 7.3 | 21 | PDB header:hydrolase Chain: A: PDB Molecule:inositol-1-monophosphatase; PDBTitle: structure of suhb: inositol monophosphatase and extragenic2 suppressor from e. coli
74 | c1s7fA_ |
| not modelled | 7.3 | 6 | PDB header:transferase Chain: A: PDB Molecule:acetyl transferase; PDBTitle: riml- ribosomal l7/l12 alpha-n-protein acetyltransferase crystal form2 i (apo)
75 | c2l2tA_ |
| not modelled | 7.2 | 14 | PDB header:membrane protein Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-4; PDBTitle: solution nmr structure of the erbb4 dimeric membrane domain
76 | c1qleB_ |
| not modelled | 7.2 | 16 | PDB header:oxidoreductase/immune system Chain: B: PDB Molecule:cytochrome c oxidase polypeptide ii; PDBTitle: cryo-structure of the paracoccus denitrificans four-subunit2 cytochrome c oxidase in the completely oxidized state3 complexed with an antibody fv fragment
77 | c1ar1B_ |
| not modelled | 7.2 | 16 | PDB header:complex (oxidoreductase/antibody) Chain: B: PDB Molecule:cytochrome c oxidase; PDBTitle: structure at 2.7 angstrom resolution of the paracoccus2 denitrificans two-subunit cytochrome c oxidase complexed3 with an antibody fv fragment
78 | c3ih5A_ |
| not modelled | 7.2 | 18 | PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: crystal structure of electron transfer flavoprotein alpha-2 subunit from bacteroides thetaiotaomicron
79 | d3clsd1 |
| not modelled | 6.8 | 12 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits
80 | c3dwcA_ |
| not modelled | 6.7 | 21 | PDB header:hydrolase Chain: A: PDB Molecule:metallocarboxypeptidase; PDBTitle: trypanosoma cruzi metallocarboxypeptidase 1
81 | d1ap4a_ |
| not modelled | 6.7 | 17 | Fold:EF Hand-like Superfamily:EF-hand Family:Calmodulin-like
82 | c2rmzA_ |
| not modelled | 6.5 | 35 | PDB header:cell adhesion Chain: A: PDB Molecule:integrin beta-3; PDBTitle: bicelle-embedded integrin beta3 transmembrane segment
83 | c1bh1A_ |
| not modelled | 6.2 | 33 | PDB header:toxin Chain: A: PDB Molecule:melittin; PDBTitle: structural studies of d-pro melittin, nmr, 20 structures
84 | c2l16A_ |
| not modelled | 6.0 | 38 | PDB header:protein transport Chain: A: PDB Molecule:sec-independent protein translocase protein tatad; PDBTitle: solution structure of bacillus subtilits tatad protein in dpc micelles
85 | d1ueka2 |
| not modelled | 6.0 | 31 | Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE
86 | c3tcvB_ |
| not modelled | 5.9 | 29 | PDB header:transferase Chain: B: PDB Molecule:gcn5-related n-acetyltransferase; PDBTitle: crystal structure of a gcn5-related n-acetyltransferase from brucella2 melitensis
87 | d1fi5a_ |
| not modelled | 5.8 | 15 | Fold:EF Hand-like Superfamily:EF-hand Family:Calmodulin-like
88 | c1fi5A_ |
| not modelled | 5.8 | 15 | PDB header:contractile protein Chain: A: PDB Molecule:protein (troponin c); PDBTitle: nmr structure of the c terminal domain of cardiac troponin2 c bound to the n terminal domain of cardiac troponin i.
89 | d1a0pa1 |
| not modelled | 5.7 | 11 | Fold:SAM domain-like Superfamily:lambda integrase-like, N-terminal domain Family:lambda integrase-like, N-terminal domain
90 | d1lf6a2 |
| not modelled | 5.6 | 14 | Fold:Supersandwich Superfamily:Galactose mutarotase-like Family:Bacterial glucoamylase N-terminal domain-like
91 | d3ehbb2 |
| not modelled | 5.5 | 16 | Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region
92 | d1yoba1 |
| not modelled | 5.4 | 18 | Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related
93 | d2fcka1 |
| not modelled | 5.4 | 16 | Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT
94 | c2b19A_ |
| not modelled | 5.4 | 22 | PDB header:neuropeptide Chain: A: PDB Molecule:neuropeptide k; PDBTitle: solution structure of mammalian tachykinin peptide,2 neuropeptide k
95 | d3dtub2 |
| not modelled | 5.3 | 19 | Fold:Transmembrane helix hairpin Superfamily:Cytochrome c oxidase subunit II-like, transmembrane region Family:Cytochrome c oxidase subunit II-like, transmembrane region
96 | c3kdpH_ |
| not modelled | 5.3 | 27 | PDB header:hydrolase Chain: H: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump
97 | c3kdpG_ |
| not modelled | 5.3 | 27 | PDB header:hydrolase Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump
98 | c3owcA_ |
| not modelled | 5.3 | 16 | PDB header:transferase Chain: A: PDB Molecule:probable acetyltransferase; PDBTitle: crystal structure of gnat superfamily protein pa2578 from pseudomonas2 aeruginosa
99 | c3fj2A_ |
| not modelled | 5.2 | 14 | PDB header:unknown function Chain: A: PDB Molecule:monooxygenase-like protein; PDBTitle: crystal structure of a monooxygenase-like protein (lin2316) from2 listeria innocua at 1.85 a resolution

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0