Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	S	S	A	K	Q	E	E	L	V	K	A	F	K	A	L	L	K	E	E	K	F	S	S	Q	G	E	I	V	A	A	L	Q	E	Q	G	F	D	N	I	N	Q	S	K	V	S	R	M	L	T	K	F	G	A	V	R	T	R	N
Secondary structure
SS confidence
Disorder		?	?	?	?																	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	K	M	E	M	V	Y	C	L	P	A	E	L	G	V	P	T	T	S	S	P	L	K	N	L	V	L	D	I	D	Y	N	D	A	V	V	V	I	H	T	S	P	G	A	A	Q	L	I	A	R	L	L	D	S	L	G	K	A	E	G
Secondary structure
SS confidence
Disorder													?	?	?	?	?																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.
Sequence		I	L	G	T	I	A	G	D	D	T	I	F	T	T	P	A	N	G	F	T	V	K	D	L	Y	E	A	I	L	E	L	F	D	Q	E	L
Secondary structure
SS confidence
Disorder																																		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3v4g chain A Region: 6 - 155 Aligned: 144 Modelled: 150 Confidence: 100.0% Identity: 72% PDB header:dna binding protein Chain: A: PDB Molecule:arginine repressor; PDBTitle: 1.60 angstrom resolution crystal structure of an arginine repressor2 from vibrio vulnificus cmcp6 Phyre2 PDB 1b4a chain A Region: 9 - 152 Aligned: 142 Modelled: 144 Confidence: 100.0% Identity: 28% PDB header:repressor Chain: A: PDB Molecule:arginine repressor; PDBTitle: structure of the arginine repressor from bacillus stearothermophilus Phyre2 PDB 3ere chain D Region: 7 - 151 Aligned: 143 Modelled: 145 Confidence: 100.0% Identity: 30% PDB header:dna binding protein/dna Chain: D: PDB Molecule:arginine repressor; PDBTitle: crystal structure of the arginine repressor protein from mycobacterium2 tuberculosis in complex with the dna operator Phyre2 PDB 1aoy chain A Region: 1 - 76 Aligned: 76 Modelled: 76 Confidence: 99.9% Identity: 100% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Arginine repressor (ArgR), N-terminal DNA-binding domain Phyre2 PDB 3cag chain F Region: 76 - 152 Aligned: 76 Modelled: 77 Confidence: 99.9% Identity: 30% PDB header:dna binding protein Chain: F: PDB Molecule:arginine repressor; PDBTitle: crystal structure of the oligomerization domain hexamer of the2 arginine repressor protein from mycobacterium tuberculosis in complex3 with 9 arginines. Phyre2 PDB 1f9n chain A domain 1 Region: 3 - 81 Aligned: 74 Modelled: 79 Confidence: 99.9% Identity: 20% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Arginine repressor (ArgR), N-terminal DNA-binding domain Phyre2 PDB 1b4a chain A domain 1 Region: 8 - 81 Aligned: 73 Modelled: 74 Confidence: 99.9% Identity: 23% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Arginine repressor (ArgR), N-terminal DNA-binding domain Phyre2 PDB 1xxa chain A Region: 82 - 154 Aligned: 73 Modelled: 71 Confidence: 99.9% Identity: 97% Fold: DCoH-like Superfamily: C-terminal domain of arginine repressor Family: C-terminal domain of arginine repressor Phyre2 PDB 1b4b chain A Region: 82 - 152 Aligned: 70 Modelled: 71 Confidence: 99.9% Identity: 33% Fold: DCoH-like Superfamily: C-terminal domain of arginine repressor Family: C-terminal domain of arginine repressor Phyre2 PDB 2p5m chain A domain 1 Region: 82 - 152 Aligned: 70 Modelled: 71 Confidence: 99.9% Identity: 36% Fold: DCoH-like Superfamily: C-terminal domain of arginine repressor Family: C-terminal domain of arginine repressor Phyre2 PDB 2p5k chain A domain 1 Region: 7 - 69 Aligned: 62 Modelled: 63 Confidence: 99.8% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Arginine repressor (ArgR), N-terminal DNA-binding domain Phyre2 PDB 1bia chain A domain 1 Region: 1 - 53 Aligned: 43 Modelled: 53 Confidence: 96.1% Identity: 21% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Biotin repressor-like Phyre2 PDB 2fe3 chain B Region: 1 - 73 Aligned: 69 Modelled: 73 Confidence: 95.4% Identity: 14% PDB header:dna binding protein Chain: B: PDB Molecule:peroxide operon regulator; PDBTitle: the crystal structure of bacillus subtilis perr-zn reveals a novel2 zn(cys)4 structural redox switch Phyre2 PDB 2xig chain A Region: 8 - 74 Aligned: 66 Modelled: 67 Confidence: 95.3% Identity: 20% PDB header:transcription Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: the structure of the helicobacter pylori ferric uptake2 regulator fur reveals three functional metal binding sites Phyre2 PDB 1mzb chain A Region: 1 - 74 Aligned: 70 Modelled: 74 Confidence: 95.2% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: FUR-like Phyre2 PDB 3eyy chain A Region: 1 - 74 Aligned: 69 Modelled: 74 Confidence: 95.1% Identity: 17% PDB header:transport Chain: A: PDB Molecule:putative iron uptake regulatory protein; PDBTitle: structural basis for the specialization of nur, a nickel-2 specific fur homologue, in metal sensing and dna3 recognition Phyre2 PDB 2w57 chain A Region: 1 - 74 Aligned: 69 Modelled: 74 Confidence: 95.0% Identity: 22% PDB header:metal transport Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: crystal structure of the vibrio cholerae ferric uptake2 regulator (fur) reveals structural rearrangement of the3 dna-binding domains Phyre2 PDB 1stz chain A domain 1 Region: 4 - 53 Aligned: 46 Modelled: 50 Confidence: 94.6% Identity: 11% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Heat-inducible transcription repressor HrcA, N-terminal domain Phyre2 PDB 3k2z chain A Region: 4 - 53 Aligned: 44 Modelled: 50 Confidence: 94.3% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:lexa repressor; PDBTitle: crystal structure of a lexa protein from thermotoga maritima Phyre2 PDB 3mwm chain A Region: 8 - 75 Aligned: 67 Modelled: 68 Confidence: 94.0% Identity: 27% PDB header:transcription Chain: A: PDB Molecule:putative metal uptake regulation protein; PDBTitle: graded expression of zinc-responsive genes through two regulatory2 zinc-binding sites in zur Phyre2 1 c3v4gA_ 2 c1b4aA_ 3 c3ereD_ 4 d1aoya_ 5 c3cagF_ 6 d1f9na1 7 d1b4aa1 8 d1xxaa_ 9 d1b4ba_ 10 d2p5ma1 11 d2p5ka1 12 d1biaa1 13 c2fe3B_ 14 c2xigA_ 15 d1mzba_ 16 c3eyyA_ 17 c2w57A_ 18 d1stza1 19 c3k2zA_ 20 c3mwmA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3v4gA_ 100.0 72 PDB header:dna binding protein Chain: A: PDB Molecule:arginine repressor; PDBTitle: 1.60 angstrom resolution crystal structure of an arginine repressor2 from vibrio vulnificus cmcp6 2 c1b4aA_ 100.0 28 PDB header:repressor Chain: A: PDB Molecule:arginine repressor; PDBTitle: structure of the arginine repressor from bacillus stearothermophilus 3 c3ereD_ 100.0 30 PDB header:dna binding protein/dna Chain: D: PDB Molecule:arginine repressor; PDBTitle: crystal structure of the arginine repressor protein from mycobacterium2 tuberculosis in complex with the dna operator 4 d1aoya_ 99.9 100 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Arginine repressor (ArgR), N-terminal DNA-binding domain 5 c3cagF_ 99.9 30 PDB header:dna binding protein Chain: F: PDB Molecule:arginine repressor; PDBTitle: crystal structure of the oligomerization domain hexamer of the2 arginine repressor protein from mycobacterium tuberculosis in complex3 with 9 arginines. 6 d1f9na1 99.9 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Arginine repressor (ArgR), N-terminal DNA-binding domain 7 d1b4aa1 99.9 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Arginine repressor (ArgR), N-terminal DNA-binding domain 8 d1xxaa_ 99.9 97 Fold:DCoH-like Superfamily:C-terminal domain of arginine repressor Family:C-terminal domain of arginine repressor 9 d1b4ba_ 99.9 33 Fold:DCoH-like Superfamily:C-terminal domain of arginine repressor Family:C-terminal domain of arginine repressor 10 d2p5ma1 99.9 36 Fold:DCoH-like Superfamily:C-terminal domain of arginine repressor Family:C-terminal domain of arginine repressor 11 d2p5ka1 99.8 19 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Arginine repressor (ArgR), N-terminal DNA-binding domain 12 d1biaa1 96.1 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Biotin repressor-like 13 c2fe3B_ 95.4 14 PDB header:dna binding protein Chain: B: PDB Molecule:peroxide operon regulator; PDBTitle: the crystal structure of bacillus subtilis perr-zn reveals a novel2 zn(cys)4 structural redox switch 14 c2xigA_ 95.3 20 PDB header:transcription Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: the structure of the helicobacter pylori ferric uptake2 regulator fur reveals three functional metal binding sites 15 d1mzba_ 95.2 19 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FUR-like 16 c3eyyA_ 95.1 17 PDB header:transport Chain: A: PDB Molecule:putative iron uptake regulatory protein; PDBTitle: structural basis for the specialization of nur, a nickel-2 specific fur homologue, in metal sensing and dna3 recognition 17 c2w57A_ 95.0 22 PDB header:metal transport Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: crystal structure of the vibrio cholerae ferric uptake2 regulator (fur) reveals structural rearrangement of the3 dna-binding domains 18 d1stza1 94.6 11 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Heat-inducible transcription repressor HrcA, N-terminal domain 19 c3k2zA_ 94.3 14 PDB header:hydrolase Chain: A: PDB Molecule:lexa repressor; PDBTitle: crystal structure of a lexa protein from thermotoga maritima 20 c3mwmA_ 94.0 27 PDB header:transcription Chain: A: PDB Molecule:putative metal uptake regulation protein; PDBTitle: graded expression of zinc-responsive genes through two regulatory2 zinc-binding sites in zur 21 c2fu4B_ not modelled 93.2 22 PDB header:dna binding protein Chain: B: PDB Molecule:ferric uptake regulation protein; PDBTitle: crystal structure of the dna binding domain of e.coli fur (ferric2 uptake regulator) 22 c2o03A_ not modelled 92.9 24 PDB header:gene regulation Chain: A: PDB Molecule:probable zinc uptake regulation protein furb; PDBTitle: crystal structure of furb from m. tuberculosis- a zinc uptake2 regulator 23 d2d1ha1 not modelled 92.9 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:TrmB-like 24 d1j5ya1 not modelled 92.8 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Biotin repressor-like 25 c2x4hA_ not modelled 92.6 16 PDB header:transcription Chain: A: PDB Molecule:hypothetical protein sso2273; PDBTitle: crystal structure of the hypothetical protein sso2273 from2 sulfolobus solfataricus 26 d1r1ua_ not modelled 92.2 26 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ArsR-like transcriptional regulators 27 c2jscB_ not modelled 91.3 22 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator rv1994c/mt2050; PDBTitle: nmr structure of the cadmium metal-sensor cmtr from mycobacterium2 tuberculosis 28 c1r22B_ not modelled 90.9 24 PDB header:transcription repressor Chain: B: PDB Molecule:transcriptional repressor smtb; PDBTitle: crystal structure of the cyanobacterial metallothionein2 repressor smtb (c14s/c61s/c121s mutant) in the zn2alpha5-3 form 29 c2oqgA_ not modelled 90.6 15 PDB header:transcription Chain: A: PDB Molecule:possible transcriptional regulator, arsr family protein; PDBTitle: arsr-like transcriptional regulator from rhodococcus sp. rha1 30 c3pqkD_ not modelled 90.6 22 PDB header:transcription Chain: D: PDB Molecule:biofilm growth-associated repressor; PDBTitle: crystal structure of the transcriptional repressor bigr from xylella2 fastidiosa 31 c2it0A_ not modelled 89.9 16 PDB header:transcription/dna Chain: A: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of a two-domain ider-dna complex crystal2 form ii 32 d1r1ta_ not modelled 89.9 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ArsR-like transcriptional regulators 33 c3f6vA_ not modelled 89.0 22 PDB header:transcription regulator Chain: A: PDB Molecule:possible transcriptional regulator, arsr family PDBTitle: crystal structure of possible transcriptional regulator for2 arsenical resistance 34 d1jhfa1 not modelled 86.8 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:LexA repressor, N-terminal DNA-binding domain 35 c2zkzC_ not modelled 86.5 21 PDB header:transcription Chain: C: PDB Molecule:transcriptional repressor pagr; PDBTitle: crystal structure of the transcriptional repressor pagr of bacillus2 anthracis 36 c2kpjA_ not modelled 86.1 9 PDB header:transcription regulator Chain: A: PDB Molecule:sos-response transcriptional repressor, lexa; PDBTitle: solution structure of protein sos-response transcriptional2 repressor, lexa from eubacterium rectale. northeast3 structural genomics consortium target err9a 37 c2o8kA_ not modelled 84.9 28 PDB header:transcription/dna Chain: A: PDB Molecule:rna polymerase sigma factor rpon; PDBTitle: nmr structure of the sigma-54 rpon domain bound to the-242 promoter element 38 c6paxA_ not modelled 84.8 21 PDB header:gene regulation/dna Chain: A: PDB Molecule:homeobox protein pax-6; PDBTitle: crystal structure of the human pax-6 paired domain-dna2 complex reveals a general model for pax protein-dna3 interactions 39 c3f6oB_ not modelled 84.6 14 PDB header:transcription regulator Chain: B: PDB Molecule:probable transcriptional regulator, arsr family PDBTitle: crystal structure of arsr family transcriptional regulator,2 rha00566 40 c3cuoB_ not modelled 84.1 17 PDB header:transcription regulator Chain: B: PDB Molecule:uncharacterized hth-type transcriptional regulator ygav; PDBTitle: crystal structure of the predicted dna-binding transcriptional2 regulator from e. coli 41 d2ev0a1 not modelled 82.7 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Iron-dependent repressor protein 42 c2kkoB_ not modelled 82.1 22 PDB header:dna binding protein Chain: B: PDB Molecule:possible transcriptional regulatory protein PDBTitle: solution nmr structure of the homodimeric winged helix-turn-2 helix dna-binding domain (fragment 1-100) mb0332 from3 mycobacterium bovis, a possible arsr-family transcriptional4 regulator. northeast structural genomics consortium target5 mbr242e. 43 c3jthA_ not modelled 81.3 25 PDB header:transcription Chain: A: PDB Molecule:transcription activator hlyu; PDBTitle: crystal structure of a transcriptional regulator hlyu from2 vibrio vulnificus cmcp6 44 c2dbbA_ not modelled 81.2 13 PDB header:transcriptional regulator Chain: A: PDB Molecule:putative hth-type transcriptional regulator ph0061; PDBTitle: crystal structure of ph0061 45 c2vbzA_ not modelled 79.9 13 PDB header:dna-binding protein Chain: A: PDB Molecule:transcriptional regulatory protein; PDBTitle: feast or famine regulatory protein (rv3291c)from m.2 tuberculosis complexed with l-tryptophan 46 c2fjrB_ not modelled 79.8 18 PDB header:transcription regulator Chain: B: PDB Molecule:repressor protein ci; PDBTitle: crystal structure of bacteriophage 186 47 c1f5tA_ not modelled 79.3 16 PDB header:transcription/dna Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: diphtheria tox repressor (c102d mutant) complexed with2 nickel and dtxr consensus binding sequence 48 c1iufA_ not modelled 79.0 19 PDB header:dna binding protein Chain: A: PDB Molecule:centromere abp1 protein; PDBTitle: low resolution solution structure of the two dna-binding2 domains in schizosaccharomyces pombe abp1 protein 49 d1u2wa1 not modelled 78.8 25 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ArsR-like transcriptional regulators 50 d1ub9a_ not modelled 75.6 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators 51 d2p4wa1 not modelled 74.8 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:PF1790-like 52 d1g3wa1 not modelled 74.8 16 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Iron-dependent repressor protein 53 c2e1cA_ not modelled 72.0 14 PDB header:transcription/dna Chain: A: PDB Molecule:putative hth-type transcriptional regulator ph1519; PDBTitle: structure of putative hth-type transcriptional regulator ph1519/dna2 complex 54 c1j5yA_ not modelled 70.4 13 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, biotin repressor family; PDBTitle: crystal structure of transcriptional regulator (tm1602) from2 thermotoga maritima at 2.3 a resolution 55 d1pdnc_ not modelled 70.1 17 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Paired domain 56 d2isya1 not modelled 69.9 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Iron-dependent repressor protein 57 d1z05a1 not modelled 69.8 10 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ROK associated domain 58 c2h09A_ not modelled 64.9 23 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator mntr; PDBTitle: crystal structure of diphtheria toxin repressor like protein2 from e. coli 59 c1fx7C_ not modelled 64.2 18 PDB header:signaling protein Chain: C: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of the iron-dependent regulator (ider)2 from mycobacterium tuberculosis 60 d1sfxa_ not modelled 62.9 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:TrmB-like 61 c2w48D_ not modelled 62.8 24 PDB header:transcription Chain: D: PDB Molecule:sorbitol operon regulator; PDBTitle: crystal structure of the full-length sorbitol operon2 regulator sorc from klebsiella pneumoniae 62 d2foka3 not modelled 60.8 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Restriction endonuclease FokI, N-terminal (recognition) domain 63 c3bdnB_ not modelled 56.9 21 PDB header:transcription/dna Chain: B: PDB Molecule:lambda repressor; PDBTitle: crystal structure of the lambda repressor 64 d2cg4a1 not modelled 56.5 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Lrp/AsnC-like transcriptional regulator N-terminal domain 65 d1i1ga1 not modelled 55.7 17 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Lrp/AsnC-like transcriptional regulator N-terminal domain 66 c2hoeA_ not modelled 55.5 15 PDB header:transferase Chain: A: PDB Molecule:n-acetylglucosamine kinase; PDBTitle: crystal structure of n-acetylglucosamine kinase (tm1224) from2 thermotoga maritima at 2.46 a resolution 67 d1foka3 not modelled 55.2 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Restriction endonuclease FokI, N-terminal (recognition) domain 68 d2b5aa1 not modelled 54.9 14 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:SinR domain-like 69 c2wteB_ not modelled 54.6 20 PDB header:antiviral protein Chain: B: PDB Molecule:csa3; PDBTitle: the structure of the crispr-associated protein, csa3, from2 sulfolobus solfataricus at 1.8 angstrom resolution. 70 c1g3wA_ not modelled 52.3 16 PDB header:gene regulation Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: cd-cys102ser dtxr 71 c2jsxA_ not modelled 52.1 11 PDB header:chaperone Chain: A: PDB Molecule:protein napd; PDBTitle: solution structure of the e. coli tat proofreading2 chaperone protein napd 72 c2e7xA_ not modelled 51.1 13 PDB header:transcription regulator Chain: A: PDB Molecule:150aa long hypothetical transcriptional regulator; PDBTitle: structure of the lrp/asnc like transcriptional regulator from2 sulfolobus tokodaii 7 complexed with its cognate ligand 73 c3sqnB_ not modelled 50.4 15 PDB header:transcription regulator Chain: B: PDB Molecule:conserved domain protein; PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis 74 c2k27A_ not modelled 50.0 16 PDB header:transcription regulator Chain: A: PDB Molecule:paired box protein pax-8; PDBTitle: solution structure of human pax8 paired box domain 75 d1au7a2 not modelled 49.7 21 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:POU-specific domain 76 c1u78A_ not modelled 49.4 10 PDB header:dna binding protein/dna Chain: A: PDB Molecule:transposable element tc3 transposase; PDBTitle: structure of the bipartite dna-binding domain of tc32 transposase bound to transposon dna 77 c2ev5B_ not modelled 49.3 25 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator mntr; PDBTitle: bacillus subtilis manganese transport regulator (mntr)2 bound to calcium 78 d1okra_ not modelled 48.8 12 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Penicillinase repressor 79 c1z05A_ not modelled 48.6 10 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, rok family; PDBTitle: crystal structure of the rok family transcriptional regulator, homolog2 of e.coli mlc protein. 80 c3cecA_ not modelled 47.0 6 PDB header:transcription Chain: A: PDB Molecule:putative antidote protein of plasmid maintenance system; PDBTitle: crystal structure of a putative antidote protein of plasmid2 maintenance system (npun_f2943) from nostoc punctiforme pcc 73102 at3 1.60 a resolution 81 d2a6ca1 not modelled 46.8 22 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:NE1354 82 c1z6rC_ not modelled 46.8 12 PDB header:transcription Chain: C: PDB Molecule:mlc protein; PDBTitle: crystal structure of mlc from escherichia coli 83 d1p6ra_ not modelled 46.7 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Penicillinase repressor 84 c3hhhA_ not modelled 45.6 20 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, padr family; PDBTitle: crystal structure of transcriptional regulator, a member of padr2 family, from enterococcus faecalis v583 85 c3iwfA_ not modelled 45.5 11 PDB header:transcription regulator Chain: A: PDB Molecule:transcription regulator rpir family; PDBTitle: the crystal structure of the n-terminal domain of a rpir2 transcriptional regulator from staphylococcus epidermidis to 1.4a 86 d1e3oc2 not modelled 44.1 25 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:POU-specific domain 87 c3ctaA_ not modelled 41.6 15 PDB header:transferase Chain: A: PDB Molecule:riboflavin kinase; PDBTitle: crystal structure of riboflavin kinase from thermoplasma2 acidophilum 88 d1y7ya1 not modelled 41.1 20 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:SinR domain-like 89 c3by6C_ not modelled 41.0 22 PDB header:transcription regulator Chain: C: PDB Molecule:predicted transcriptional regulator; PDBTitle: crystal structure of a transcriptional regulator from oenococcus oeni 90 c3hhgF_ not modelled 40.5 25 PDB header:transcription regulator Chain: F: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: structure of crga, a lysr-type transcriptional regulator from2 neisseria meningitidis. 91 d3bl9a2 not modelled 40.1 14 Fold:mRNA decapping enzyme DcpS N-terminal domain Superfamily:mRNA decapping enzyme DcpS N-terminal domain Family:mRNA decapping enzyme DcpS N-terminal domain 92 d1adra_ not modelled 38.8 18 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:Phage repressors 93 c3op9A_ not modelled 38.3 21 PDB header:transcription regulator Chain: A: PDB Molecule:pli0006 protein; PDBTitle: crystal structure of transcriptional regulator from listeria innocua 94 c3eusB_ not modelled 38.3 15 PDB header:dna binding protein Chain: B: PDB Molecule:dna-binding protein; PDBTitle: the crystal structure of the dna binding protein from silicibacter2 pomeroyi 95 c2l4aA_ not modelled 37.0 10 PDB header:dna binding protein Chain: A: PDB Molecule:leucine responsive regulatory protein; PDBTitle: nmr structure of the dna-binding domain of e.coli lrp 96 c1b0nA_ not modelled 34.8 27 PDB header:transcription regulator Chain: A: PDB Molecule:protein (sinr protein); PDBTitle: sinr protein/sini protein complex 97 c3ispA_ not modelled 34.3 21 PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional regulator PDBTitle: crystal structure of argp from mycobacterium tuberculosis 98 d2cyya1 not modelled 34.0 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Lrp/AsnC-like transcriptional regulator N-terminal domain 99 c3mkzU_ not modelled 33.8 20 PDB header:dna-binding protein/dna Chain: U: PDB Molecule:protein sopb; PDBTitle: structure of sopb(155-272)-18mer complex, p21 form 100 c2qfcB_ not modelled 33.7 30 PDB header:transcription regulation Chain: B: PDB Molecule:plcr protein; PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr 101 c1xmlA_ not modelled 33.4 14 PDB header:chaperone Chain: A: PDB Molecule:heat shock-like protein 1; PDBTitle: structure of human dcps 102 d1lfpa_ not modelled 33.0 13 Fold:YebC-like Superfamily:YebC-like Family:YebC-like 103 c3frwF_ not modelled 32.6 16 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:putative trp repressor protein; PDBTitle: crystal structure of putative trpr protein from ruminococcus obeum 104 c2qwwB_ not modelled 32.5 14 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, marr family; PDBTitle: crystal structure of multiple antibiotic-resistance repressor (marr)2 (yp_013417.1) from listeria monocytogenes 4b f2365 at 2.07 a3 resolution 105 c3t1bB_ not modelled 32.2 15 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: crystal structure of the full-length aphb n100e variant 106 d2fxaa1 not modelled 32.1 17 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators 107 d1y9qa1 not modelled 31.4 13 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:Probable transcriptional regulator VC1968, N-terminal domain 108 d1ixca1 not modelled 31.3 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:LysR-like transcriptional regulators 109 d1b0na2 not modelled 31.3 24 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:SinR domain-like 110 d1iufa1 not modelled 30.8 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Centromere-binding 111 c3g3zA_ not modelled 30.8 20 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, marr family; PDBTitle: the structure of nmb1585, a marr family regulator from neisseria2 meningitidis 112 d2cfxa1 not modelled 30.4 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Lrp/AsnC-like transcriptional regulator N-terminal domain 113 c1i1gA_ not modelled 29.8 15 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator lrpa; PDBTitle: crystal structure of the lrp-like transcriptional regulator from the2 archaeon pyrococcus furiosus 114 c3fmyA_ not modelled 29.3 26 PDB header:dna binding protein Chain: A: PDB Molecule:hth-type transcriptional regulator mqsa PDBTitle: structure of the c-terminal domain of the e. coli protein2 mqsa (ygit/b3021) 115 c2ppxA_ not modelled 29.3 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu1735; PDBTitle: crystal structure of a hth xre-family like protein from agrobacterium2 tumefaciens 116 d2ppxa1 not modelled 29.3 21 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:SinR domain-like 117 c3fzjC_ not modelled 28.6 15 PDB header:transcription regulator Chain: C: PDB Molecule:lysr type regulator of tsambcd; PDBTitle: tsar low resolution crystal structure, tetragonal form 118 c1iz1B_ not modelled 27.5 15 PDB header:dna binding protein Chain: B: PDB Molecule:lysr-type regulatory protein; PDBTitle: crystal structure of cbnr, a lysr family transcriptional2 regulator 119 d2esna1 not modelled 27.2 31 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:LysR-like transcriptional regulators 120 c2o38A_ not modelled 27.1 37 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: putative xre family transcriptional regulator

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0