Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	L	N	P	G	Q	Q	Q	A	V	E	F	V	T	G	P	C	L	V	L	A	G	A	G	S	G	K	T	R	V	I	T	N	K	I	A	H	L	I	R	G	C	G	Y	Q	A	R	H	I	A	A	V	T	F	T	N	K	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	E	M	K	E	R	V	G	Q	T	L	G	R	K	E	A	R	G	L	M	I	S	T	F	H	T	L	G	L	D	I	I	K	R	E	Y	A	A	L	G	M	K	A	N	F	S	L	F	D	D	T	D	Q	L	A	L	L	K	E	L
Secondary structure
SS confidence
Disorder															?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	E	G	L	I	E	D	D	K	V	L	L	Q	Q	L	I	S	T	I	S	N	W	K	N	D	L	K	T	P	S	Q	A	A	A	S	A	I	G	E	R	D	R	I	F	A	H	C	Y	G	L	Y	D	A	H	L	K	A	C	N	V
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	D	F	D	D	L	I	L	L	P	T	L	L	L	Q	R	N	E	E	V	R	K	R	W	Q	N	K	I	R	Y	L	L	V	D	E	Y	Q	D	T	N	T	S	Q	Y	E	L	V	K	L	L	V	G	S	R	A	R	F	T	V	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	D	D	D	Q	S	I	Y	S	W	R	G	A	R	P	Q	N	L	V	L	L	S	Q	D	F	P	A	L	K	V	I	K	L	E	Q	N	Y	R	S	S	G	R	I	L	K	A	A	N	I	L	I	A	N	N	P	H	V	F	E	K
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	L	F	S	E	L	G	Y	G	A	E	L	K	V	L	S	A	N	N	E	E	H	E	A	E	R	V	T	G	E	L	I	A	H	H	F	V	N	K	T	Q	Y	K	D	Y	A	I	L	Y	R	G	N	H	Q	S	R	V	F	E	K
Secondary structure
SS confidence
Disorder					?	?	?	?																														?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		F	L	M	Q	N	R	I	P	Y	K	I	S	G	G	T	S	F	F	S	R	P	E	I	K	D	L	L	A	Y	L	R	V	L	T	N	P	D	D	D	S	A	F	L	R	I	V	N	T	P	K	R	E	I	G	P	A	T	L	K	K
Secondary structure
SS confidence
Disorder																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		L	G	E	W	A	M	T	R	N	K	S	M	F	T	A	S	F	D	M	G	L	S	Q	T	L	S	G	R	G	Y	E	A	L	T	R	F	T	H	W	L	A	E	I	Q	R	L	A	E	R	E	P	I	A	A	V	R	D	L	I	H
Secondary structure
SS confidence
Disorder																							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		G	M	D	Y	E	S	W	L	Y	E	T	S	P	S	P	K	A	A	E	M	R	M	K	N	V	N	Q	L	F	S	W	M	T	E	M	L	E	G	S	E	L	D	E	P	M	T	L	T	Q	V	V	T	R	F	T	L	R	D	M	M
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?																						?	?	?	?	?	?	?													?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		E	R	G	E	S	E	E	E	L	D	Q	V	Q	L	M	T	L	H	A	S	K	G	L	E	F	P	Y	V	Y	M	V	G	M	E	E	G	F	L	P	H	Q	S	S	I	D	E	D	N	I	D	E	E	R	R	L	A	Y	V	G	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?																															?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		T	R	A	Q	K	E	L	T	F	T	L	C	K	E	R	R	Q	Y	G	E	L	V	R	P	E	P	S	R	F	L	L	E	L	P	Q	D	D	L	I	W	E	Q	E	R	K	V	V	S	A	E	E	R	M	Q	K	G	Q	S	H	L
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?	?	?	?	?	?	?	?																	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.
Sequence		A	N	L	K	A	M	M	A	A	K	R	G	K
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1uaa chain B Region: 2 - 642 Aligned: 633 Modelled: 641 Confidence: 100.0% Identity: 100% PDB header:hydrolase/dna Chain: B: PDB Molecule:protein (atp-dependent dna helicase rep.); PDBTitle: e. coli rep helicase/dna complex Phyre2 PDB 2is6 chain B Region: 2 - 659 Aligned: 643 Modelled: 658 Confidence: 100.0% Identity: 37% PDB header:hydrolase/dna Chain: B: PDB Molecule:dna helicase ii; PDBTitle: crystal structure of uvrd-dna-adpmgf3 ternary complex Phyre2 PDB 1w36 chain E Region: 1 - 659 Aligned: 623 Modelled: 631 Confidence: 100.0% Identity: 20% PDB header:recombination Chain: E: PDB Molecule:exodeoxyribonuclease v beta chain; PDBTitle: recbcd:dna complex Phyre2 PDB 1pjr chain A Region: 2 - 642 Aligned: 610 Modelled: 628 Confidence: 100.0% Identity: 42% PDB header:helicase Chain: A: PDB Molecule:pcra; PDBTitle: structure of dna helicase Phyre2 PDB 3lfu chain A Region: 2 - 639 Aligned: 621 Modelled: 627 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: A: PDB Molecule:dna helicase ii; PDBTitle: crystal structure of e. coli uvrd Phyre2 PDB 2pjr chain F Region: 2 - 540 Aligned: 535 Modelled: 539 Confidence: 100.0% Identity: 40% PDB header:hydrolase/dna Chain: F: PDB Molecule:protein (helicase pcra); PDBTitle: helicase product complex Phyre2 PDB 1w36 chain F Region: 26 - 633 Aligned: 595 Modelled: 608 Confidence: 100.0% Identity: 15% PDB header:recombination Chain: F: PDB Molecule:exodeoxyribonuclease v gamma chain; PDBTitle: recbcd:dna complex Phyre2 PDB 1uaa chain A domain 2 Region: 308 - 640 Aligned: 330 Modelled: 330 Confidence: 100.0% Identity: 98% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 1uaa chain A domain 1 Region: 2 - 307 Aligned: 306 Modelled: 306 Confidence: 100.0% Identity: 100% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 1pjr chain A domain 1 Region: 2 - 309 Aligned: 304 Modelled: 308 Confidence: 100.0% Identity: 45% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 1w36 chain B domain 1 Region: 1 - 307 Aligned: 299 Modelled: 301 Confidence: 100.0% Identity: 23% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 1pjr chain A domain 2 Region: 311 - 640 Aligned: 302 Modelled: 304 Confidence: 100.0% Identity: 39% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 1w36 chain B domain 2 Region: 320 - 629 Aligned: 278 Modelled: 282 Confidence: 100.0% Identity: 17% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 2wjy chain A Region: 1 - 611 Aligned: 360 Modelled: 373 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:regulator of nonsense transcripts 1; PDBTitle: crystal structure of the complex between human nonsense2 mediated decay factors upf1 and upf2 orthorhombic form Phyre2 PDB 2xzl chain A Region: 2 - 611 Aligned: 362 Modelled: 376 Confidence: 100.0% Identity: 20% PDB header:hydrolase/rna Chain: A: PDB Molecule:atp-dependent helicase nam7; PDBTitle: upf1-rna complex Phyre2 PDB 1qhh chain B Region: 159 - 419 Aligned: 261 Modelled: 260 Confidence: 100.0% Identity: 46% PDB header:hydrolase Chain: B: PDB Molecule:protein (pcra (subunit)); PDBTitle: structure of dna helicase with adpnp Phyre2 PDB 1w36 chain C domain 2 Region: 299 - 633 Aligned: 332 Modelled: 335 Confidence: 100.0% Identity: 17% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 2gk7 chain A Region: 2 - 611 Aligned: 361 Modelled: 375 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:regulator of nonsense transcripts 1; PDBTitle: structural and functional insights into the human upf1 helicase core Phyre2 PDB 1qhh chain A Region: 2 - 155 Aligned: 153 Modelled: 154 Confidence: 100.0% Identity: 45% PDB header:hydrolase Chain: A: PDB Molecule:protein (pcra (subunit)); PDBTitle: structure of dna helicase with adpnp Phyre2 PDB 3e1s chain A Region: 1 - 611 Aligned: 339 Modelled: 354 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:exodeoxyribonuclease v, subunit recd; PDBTitle: structure of an n-terminal truncation of deinococcus radiodurans recd2 Phyre2 1 c1uaaB_ 2 c2is6B_ 3 c1w36E_ 4 c1pjrA_ 5 c3lfuA_ 6 c2pjrF_ 7 c1w36F_ 8 d1uaaa2 9 d1uaaa1 10 d1pjra1 11 d1w36b1 12 d1pjra2 13 d1w36b2 14 c2wjyA_ 15 c2xzlA_ 16 c1qhhB_ 17 d1w36c2 18 c2gk7A_ 19 c1qhhA_ 20 c3e1sA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499