>ss_pred
CCCCEEEEECCCCEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCEEECHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHCHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCC
>ss_conf
99851899258976016989999999998607788898999999985228998799999999999986225368889999999999999998730100134899998665315314789999979999999976343200015978999998731221778980560999999999999731386321168999999999739802278321068888887258240587699889999999999999632950310236466886143679978750169999999999998279373415899868812289899851557764221001012132699999999739981456656733220234332788999999863078704664059999999999999728952781124402288743477587007642111345555554454575100001430288820899999999999999999986047881899998863197037202479899973899899899999999999999999999999998728998777780000322155531011223344111698999999987282101102357732899981999882867310689972788520336835754652340000485899999999762320152201587257668866789999999999999729707833226420234432100111003436342119
>batch____
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>UniRef50_P74240(33-763:767) Ribonucleoside-diphosphate reductase subunit alpha n=12 Tax=Cyanobacteria RepID=RIR1_SYNY3  E=6e-76 s/c=0.39 id=32% cov=92%
------VIRRDGSSTPLNIGKIRAVVDWACLGLEVNSIA-LEAGLTTRLREGISTREIQDNLISCALEMCSPNEPDWRYVAGRLHVWSLWKDTlvrrgyqYGQY-----LRTVQTKVTNGEYDSRILT-YSEGELQEAGCWINSDWDTDYDYAGAVLLTSRYLLPNELPQEALLTCALLLASVEA-------PDRRLQWARRFYESIAARRISLATPILANLRVPGGSLTSCFIVAMEDNLESIFGEITNAARISKNGGGVGVNVSRIRATGSWVMGKPNASGGVIPWTKLLNDTAIAVNQGGRRAGAVTVGLDVWHLDVPEFLEMQAENGDQRRKAYDIFPQLILPDEFMRRVINKEDWTLVDPYEVREKMGIELAElwGEQFEGAYREIESnlDTTITlYKRINARELFKQIMRTQVETGMPYLSFKDTINKANP-NKHLGYIPGTNLCCESFSNVTPGQDAH-------CCNLVSLNLANL-DLQDIAGVSQIAVRMLDNTIELTAPPFADAKSHNNKYRTIGVGAMGLADWLAKRRLNYDELADIN---RLFEEIGYWCTQSSMELAKERGAYPAFPGSDWQKGLLigskPVSWFQ------ANAAKPERWEKLSNDIQTHGIRNSHITAIAPNTSSSLVQGCTASILP----VYSRFFYDKWAKGTVPIAPPFIG--NCFWFYPENKTMdqrkvVKAVAAIQQWTDTGISMellfNLNagiYFPEE-PERSLNAKDIFDTLVMAWEAGCKAIYYIRTvqKDDFKDSSDGCV---------------
>UniRef50_B4E5V9(163-810:1003) Ribonucleoside-diphosphate reductase n=71 Tax=cellular organisms RepID=B4E5V9_BURCJ  E=4e-71 s/c=0.42 id=34% cov=81%
----------NGVTRPLDLNALRALIVSACDGLgAAVNPDPIVAETVKNLYDGVPMSQVYDSAILAARTMIEKD-PAYSQVTARILLHTIRREILGeevvQAEMSTRYaeyfpQFLKRGVDAGLLDDKLL----QFDLKRLGEALDANRDLQFGYLGLQTLYDRYFLH--VDGTRIEMPQAFFMRVAMGLSLNeIDRETR---AIEFYNVLSSFDFMSSTPTLFNSGTHRSQLSSCYLTTVADDLDGIYEALKENALLSKFAGGLGNDWTRVRALGSHIKGTNGKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLESWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVMEGADWTLFSPSTCPDLHDKFGAD---FEKAYTAYE--DKVARGEIKlfkkipAQQLWRKMLGMLFETGHPWITFKDPCNVRSP-QQHVGVVHSSNLCTEITL--------NTSDTEIAVCNLGSVNLVAhlvkqadgsyALDHDKLKRTISVAMRMLDNVIDINYYAVPKARNSNLKHRPVGMGIMGFQDCLHLLRTPYASEAAVEFADRSMEAVCYYAYYASTELAEERGRYSSYRGSLWDRGILPQDTLKlltearggyVEVDT--SESL--DWTTLRSRIAAHGMRNSNCVAIAPTATISNIIGVSACIEPTFQNLYVKSNLSG---------------------------------------------------------------------------------------------------------------
>UniRef50_C1FEX6(3-780:841) Ribonucleoside-diphosphate reductase n=4 Tax=Chlorophyta RepID=C1FEX6_9CHLO  E=1e-69 s/c=0.34 id=34% cov=93%
----MYVVKRDGRQEPVHFDKITARINKLAYGLNQEFCDPVLVaqKVAVGVYKGVTTSELDELAAETAASMTSKH-PDYAQLAARIAVSNLHKNTLKSFSEtmKVMYEHVNK--RNGKWSPLLADDVYEiikENADRFDSEIVYDRDFDYDYFGYKTLERSYLL--RVDGKIVERPQHLLMRVAIGIHKDVEKAIDT------YHMLSERWMTHASPTLFNSGTPRPQLSSCFLIAMKeDSIEGIYDTLKECACISKSAGGIGLSIHDIRATSSYIRGTNGTSNGIIPMLRVFNDTARYVDQgGGKRKGAFAIYLEPWHADIFDWLDLRKNHGKEEARARDLFYGLWTNDLFMKRVEANGEWTLFCPNEAPGLADCW---GEEFEALYEKYEAEGKGKKT-VKAQQLWFAILESQVETGNPYMLFKDACNRKSN-QQNLGTIRSSNLCTEIVEYTSP--------EETAVCNLASIALprfviennpqsptgrteakklrgsiGAANryfDHDKLAEITRKVTRNLNRIIDVNYYPVETARRSNMKHRPIGLGVQGLADVFILLGMPFDSPEAKKLNAEIFETIYFAALTESNDIAKRDGTYESYPGSPVSNGVLQPDMW--GLTEMPGGDRH-DWTGLRTKISEHGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYARRVLSGEF--TVVNQHLLSDLTEMgLWdpslknELIANNGSVQSLDIPDNlkeiyktvweikqrilvdmaadrgaFIDQSQSFNVHMSDAN--SGKLTSLHFY-----AWKKGLKTgMYYLRSRAAADAVKFTVDPN-------------
>UniRef50_B0RGP9(2-757:834) Ribonucleoside-diphosphate reductase n=15 Tax=Bacteria RepID=B0RGP9_CLAMS  E=8e-64 s/c=0.33 id=29% cov=92%
---SITVVKRDGSKEPYDANRINLAIEDATQGLdENIGwVTQIASELEITLFDGITTQQLDEAVIQVALQNV-KDDPAFDTVAARLLLKTIYKRVLGDYSSPEELkrlhaEHFARNIQRG-VDEMLLDSRLVQLFdlERLAQALEPAHDELLKYIGVVTLNNRYGIKGR-NGDALEVPQYFWMRIAMGLTLNeqNPTETAIA----FYEKMSKLEYLAAGSTLVNAGTIYPQLANCFVMEMQDDIEHIAKTTRDVMWLTKGTGGIGLSVSKLRAQGSPIRSNNTTSTGPIPFMHTIDSVLRAVSRGGKKFGALCFYMENWHLDFPEFLDLRQNSGDPYRRTRTANTAVWISDEFMKRVQNDEDWYLFDPlevSDLNELYGKAFSERYAF---YVGEAEAGRIRMfKRINAREQFKSILISLQTTSHPWLTWKDTINNRA-LNNNTGTIHLSNLCTEITLP-------QDEDN-VSVCNLASINLSqhfADGKVDfaKIEQSARLAVRQLDNLIDITRSSVKEADFSNQQNRAVGLGVMGFTDIVEKLGFSYESEESYDLIDEIMEHVSYAAIDESADLAKERGAYPNFEGSRWSEGLVPLDSIAlmeadRGVPVKVNRTTRLDWDALRAKVK-GGMRNATLMAIAPTASIGLVAGTTPGLDPQFSQIFSRSTSSGkfleVNRNLVKDLQELG-----IWETVRENilrsqgdiqniaaipdhvkatyrtsfqlspyAFLEVAARAQKWIDQAISRNM-YLETR------DLGDMMDIYFAGWERGVKTTYY------------------------------
>UniRef50_C1VDU7(2-761:845) Ribonucleoside-diphosphate reductase n=1 Tax=Halogeometricum borinquense DSM 11551 RepID=C1VDU7_9EURY  E=2e-62 s/c=0.32 id=33% cov=90%
-----------------QTNDVRTILNQARTGYEDVLTDEVMDRlvteTERNLYDGASIDEVYEALEGVTTARIERD-PAYKYVAADIHRRRYFRRVTGeQLSETADDDTATTYRETfaANLERGVDEDLLDERLLDGRFDIDEladalvlERDDKFDYIAMSTLTQRYFIKTEVDGDPLELPQAFWMRVAMGLAieEDDPQARALE----FYDVLSRllFTPSTPTLFHSGTTHP--QLSSCYLTTVEDDLEHIFDSYKHHAQLSKWSGGLGNDWTNLRAEGALIESTGVESTGTVPFLKISNDVTAAINRSGKRRGAACGYLEAWHMDFPAFLDLRRNTGDERRRTHDMNTAAWVPDLFMERVENDETWTLFSPDEVPELHETY---GEEFAELYREYEEKAEAGELRqyetVDAADLWRTMLTRLFETGHPWITFKDPCNVRSPQD-HVGTVHSSNLCTEITLNTSA--------EEHAVCNLGSVNLSNHVADSELDREALadtieTATRMLDNVVDLCFYPTDEAEYSNMRHRPVGLGVMGFHDALMQVGTSMASEEAVEAANRWQEFVSYHTILNSSRLAKERGAYETFEGSKWDRGILPHDTVDrleaergREIPTDRSETM--DWDRVRDHIAEHGMRNSNTMAIAPTATISTINGTTPSIEPIYSNLYVKSNMSGdftvINEQLVDDLkaEGLWDD-EMVDQIKFFDGSIQEVSAIPeemrelyrsafeidprhqlrltahrgQWIDQSISHNV-----FFPSTD---GSLLDDVYkTAWRLGVKTTYYLRT---------------------------
>UniRef50_A4XD09(115-849:909) Ribonucleoside-diphosphate reductase n=44 Tax=Bacteria RepID=A4XD09_SALTO  E=3e-59 s/c=0.32 id=31% cov=90%
----MGVRKRNGDTEPVDVNKIVRAVErWVAD-LDEVDPLRVATKTISGLYDGATTAELDRLSIQTAAELIGEE-PQYSKLAARLLAAYVDKEVRGQqvasFSQSIRYAHGLGLI------SDETAAFVSRNARKLDDAVDPAGDLRFEYFGLRTVADRYLLRHPQSRLVVETPQY-WLLRVACGLSGTPAE-----AIGFYRLMSSLAYlpSSPTLFNSGTRHT--QMSSCFLVDSPrDELDSIYQRYHQVAKLSKFSGGIGIAWSRVRGRGALIRGTNGRSNGIVPFLKTLDAGVAAVNQGGRRKGAACVYLEPWHPDIEEFLELRDNTGEDARRTHNLNLANWLPDEFMRRVEADGDWSLIDPSEAPELPDLY---GEEFDAAYRVAEK-KAVRT--VKARDLYGRMMRTLAQTGNGWMTFKDRSNTLSnqTGEPGNT-IHLSNLCTEIL-------EVNN-DAETAVCNLGSVNLGAHVTADgvdweKLRDTVRTAVVFLDRVIDINYYPAEQAAASNPRWRPVGLGLMGLQDAFFTLRLPFDSAEASELSTRVQEEIFLTALETSAGLAERFGPHPAYAQTRAARG----DLHPELWGAVPSQPQR--WAGLKARVGEHGLRNSLLVAIAPTATIASIAGCYECIEPqvsnlfkretmsgeflqvntylvgelkARGLwtASIRdqiKRAEGSVQGLAELPAEVRELFRTAWELP-QRALIDLAAARAPYIDQSQSLNL------FLAAPT-IGKLSSMYLYAWKSGLKTTYYLRSR--------------------------
>UniRef50_C7NVI1(10-755:815) Ribonucleoside-diphosphate reductase n=2 Tax=Halobacteriaceae RepID=C7NVI1_HALUD  E=1e-57 s/c=0.30 id=31% cov=89%
-------------------DRIASILDRATDGEPTVTESdRTALRRAIdeNCYAGADRAEVYEAILGTLSARIEA-KPAYKRVAARV----FRQRYYHEVIGEDLTgteldrayrtifrENIERGVATDLLDTRLVDRF---DLDALAEYLAPERDEHFEYLAMETLYQRYFLRTN-DGEHLELPQAFWMRVAMGL--AVEEDDPNARAKEFYDVLSKLEFTPSTPTLFHSGTTHPQLSSCYLTTVPDDLEGIFDAYKHHAQLSKWSGGLGNDWTPLRAEGALIESTGVESTGVVPFLRISNDVTAAINRSGKRRGAACAYLAIWHLDFPAFVDLKRATGDERRRTPDMNTAAWIPDLFMERVQAGESWTLFSPDEVGDLHEAT---GEAFAEKYREYEQaaenGDIENFETVEAAELWRTLLTRLFETGHPWVTFKDPCNIGSPQDHE-GTIRSSNLCTEITL--------NTSTDEHAVCNLGSVNFathmrdGELDR-DYLEDTVETAMRMLDNVVDLCFYPTEEAEDSNMRHRPVGLGTMGFHEALMEIGVPMNSNEAVEKANRWQEFVAYHAIRTSSELAGERGAYPSFEGSKWDRDILPQDTVDlleeergREIPTERTETL--EWDAVRKSIAEHGMRNSNTMAIAPTATVSTINGTTASIEPQYSNLYVKSNmsgdftivndhlvadlrerdlwddemrdrikyHDGSIQEIEAIPEDLRELYRGAFEIDPRH-QLRLTAHRQTWIDQSVSHNVF-----FPSTD---GTLLDDIyTTAWELGLKTTYYLRT---------------------------
>UniRef50_Q8JKL8(7-657:939) Ribonucleoside-diphosphate reductase n=1 Tax=Heliothis zea virus 1 RepID=Q8JKL8_9VIRU  E=2e-55 s/c=0.34 id=30% cov=82%
-----MIVKRNGSVERFDPSKlyarIERCMTMSEPRLTTAFINIAGIVADVEkgLYDRVSTLEL-DTLLSETCASMSTAHPDHSILAARIAMQALHKRTRSKFS-----ETIRDLYEANIVPQYYF-DLVQEHADTLDSAIVDDRDFqSLTYFAYKTLERTYLIK-LADGKICERVQHMYMRTALGIHGR-----DIESVIETYNLLSNRYYVHSTPTLCHAATNRSNYASCYLLELKeDSIGGVMDTLKDAATISKHCGGVGLHVHKLRCKNSTIHSTNGNASGLVPMLRMYNAMSRYVTQGGnKRPGAIAVYLEPWHADVFDFIEMRKNSGFEEARARDLFYALWVPDLFMKRVNDGGYWSLMCPDSSPGLSDCW---GEEFEAKYTAYEQEGRYVR-RVDARELWKAIVTAQVETGTPYILYKDTVNRNSN-QRHLGTIKGSNLCTEIVEYASP--------DETAVCVLASVNLpkfveGKVFNLNLLAKTVRLVTRNLNKIIDNALYPIPSAAKSNFKHRPIGIGVQGYADALAMMGIAYED--SMQLNRDIFETIYHAALTESCQLARVHGVYESYHGSPTSRGELHFDRY-----SVHSQKC--DWSSLRKDIARYGLRNSLLVAPMPTATTSQVFGNAESFEPFTSNMYQRRTQSGEFQltnvHLVRDLERLN--------------------------------------------------------------------------------------------------
>UniRef50_Q75BW6(58-793:864) Ribonucleoside-diphosphate reductase n=2 Tax=Saccharomycetaceae RepID=Q75BW6_ASHGO  E=1e-53 s/c=0.29 id=32% cov=88%
----------------------------------------------------IRDSELVAYIGETLASMITRH-PDFSLLAARVEIKVLHKRLLGL----GFTGNLAVLCESGDSpEGHAtkrkramspctrgpvrreLYDLAVQHRNIIDQAIDDTLDFTFTYFGWKTLCKSYLLKHQ--GRVHETPQYMFMRVALALHGPSGDIDRVLETYRLM-ANKYFIHASPTLFNAG--TTSQFLSSCFLL--GIHEDSIDGIYNALHKAAlisKASGGIGIHVSDIRANGSYISGTNGTSNGLVPMLSVFNSTARYVDQGGnKRPGAFCIYLEPWHADVFDFLRLRRNHGKEEMRARDLFYGLWIPDLFMKRVENNGEWSLFSPNEAVGLSDCY---GEAFEQLYVRYERELEPYR-RVKAQELWREILLSQTETGGPFMLYKDACNSKSN-QKNLGTIKSSNLCCEIVEYSS--------RDEVAVCNLASVALPTFVSVTsdaitfdyaRLHSVVKVMTRNLDKAIDIGDYPVPEAERSNKKHRPLALGVQGLADVFMLMRFPFNGEEAAQMNREIFETIYHAAVETSIELAAEYGVYASFVGSPASKGELQFDLWGRNKDNY--QFLYDDWDELKEKIKSGpGLRNSLLVGPMPTASTSQILGFTESFEPMTSMIYTRRVLSGeytlVNKYMVQDFcdlgiwseelknriikdggsiqgidgipPDLKDLYKTVWELPQRK-LIDLSADRAPFVDQSQSLNLFLkEPT--------MGKLTSMHFYAWKKGLKTgMYYLRTQAAANAIQFTLT----DENTLSGPVKL
>UniRef50_B7XJ88(62-778:778) Ribonucleoside-diphosphate reductase n=2 Tax=Enterocytozoon bieneusi H348 RepID=B7XJ88_ENTBH  E=5e-53 s/c=0.30 id=30% cov=86%
--------------------------------------------------------------------------PSYNKLAAIILIKHLHENTFNTFSDKMMYIQQEKNI----FDDHIME-LIINNMNVYNSIVKYERDYNFDYFALISLQKSYQIQ--VNNTVIERPQDIYMRVAIELHGD-----DFNNVQKTYDLLSQQYYTHATPTLYNSCFKKNQLASCFLLGMkSDTIAGIFDTIKEAAIYSKLSGGVGLHISNLRCDKSQLVTTGGYSKGIIPIVKLINDSMKYINQGGARRCATCAFYlEPWHKDILKFLDLRKNTGIEEERARDSFTALWINDLFMERVEKNEMWSLFDPNIAKGLQDV-WGDQ--FNKLYAYYE--ETIERTTIPAQKLWKEIICSQIETGTPYMCYKDTCNRYSN-QNNIGTIKSSNLCAEI---------IQYSDSDItAVCNLASICLPkyvKINsttsnyyfDFQELYTVVKIVTYNMNKMIDKSAFPTEESKKGNSLFRPIGIGVQGLADVFFLMGYSFESKEARDLNKMIFETLYFGALEASCELAQKHGPYSYYQGSMYSQGIFHFEKFCEGRINV-NEILSgmWNWEELRIKMKTYGVRNSLTLALMPTASTSQICGNSECIEPIQSNIFTRRTfagefqivnkylmKDLIklglwnneIKQLIIEYEgsiqkipiipqHVKDLYKTVWELKMK-SVLDMAIDRQAFVDQSQSLNLFVkEPTygilssmHFYGWKNKLKTGMYYLRTcplakAIKFTVDKELILKTLSSFKDSENDKKLNKENDYCEGCSC--
>UniRef50_B2V806(4-754:850) Ribonucleoside-diphosphate reductase n=2 Tax=Aquificales RepID=B2V806_SULSY  E=1e-44 s/c=0.25 id=30% cov=89%
-HKNRIVVKRDGTQEKFQMKKLVDAIFALLEGLDLPDdyeiVFKITKELDLKIPEVVTTEELDYLVLKAIEHLIPTGSI-YDTIATRqlLKIINRRiERRFSSFKDYINYAVNEKLLkpELLNFDIDLLE-----------SKIDYSRDNNLDYFGLSTLKDRYLTKDR-NFETIEKPQWFFMRVAMGI-GNTEEE-----ILKIYDKLSNLEYLHSTPTLFNSGTLTNQYSSCYVNVVDDSLESIMDKAKETAFLAKYAGGVGTDITRIRATGSKIHSLNAKSSGIIPFIKIFDTIVNAIQQGGRRRSSQVMYLQPWHLDVEAFLDLRETTGNPYFRTPSLNTALWMPDEIMRRIKEGEPIYLFDPAECRELVTSY---GEEFAKKYQecieKAERGELELWKKIDSRDFYKKYLFKLAKTGHPWLTFKDAHNRHNPC-PKYSVINSSNLCTEISIPNSPQS--------TAVCTLASVNLArhlkkveretsdvkreelSPNekntshlltyspthsiDWDKLKDTLETMVVALDNILDKNFYPSEESRKNTMDLRPIGIGLMGFHEALIYLGIPYDSDEAIELAKEIAKFMRETVYRKSEELAKERGAFPHYYEVS-----------KRESEKVKSEELNPN-----EKTPTHLLtyspthpynypprRNAVLLAIAPTASISIIAGTSSSID---NYFSNIFSRDTLSGKFIvvnkPLMKMLEEKgiwnEEMLEKIKANQGSIQYIDELEGVVDKRL-FKTAYEVS-------PYRQI--DIAAAFQQYIdqavsKSLYIE------EDLRDDM----------------
>UniRef50_UPI0001792B32(4-688:766) PREDICTED: similar to AGAP010198-PA n=1 Tax=Acyrthosiphon pisum RepID=UPI0001792B32  E=4e-33 s/c=0.21 id=26% cov=84%
LKKHLYVQKRDGTIEKVHYDEIIARIKQLCYGLEKIDPAATAIHVIKKcLFAGITTSQLDD----AAAEMaitMATIHPDYEKLAARIAISNLHKQTKEKFSD--VIDDIHKNDDY--WNTGLSDDIYEIIMKNKDRLneaINYENDYILDYFGFKYLTQNFLVKSE--NQTIERPQHLFMKVAVGIHGD-----DIDSAIETYKMLSQ-KLCMFSPVVMQLQPAARKLNVSVISHysvamIADSIDGIYDTLNRLSTFILPYSSVAVHVHKIRAAGTYIKGSNGKSSGLPLMLKQYDSMV-HCKEtlerpKSIKGVA--IYCELWHADIMKIIDQIRKTTIADIKLKNSQLALWIPDEFMRRVENDQMWSFMSPDHCPGLIDVH---GEEFDNLYKEYElKSKSFVMRQIEAKKLWSQIIQSQIETGLPLLLFKDACNAKS---------NESHLG-TIQCAGRNGDTVQfTASDEVATCTTASISVDMfltsenIFDFSKLKETAKKITYDLNKIIENNNVILNKEDQLKLGLKqnqlAIGIGIQGLADLFIKMRYPFDNKEARYLNIQIHETIYYGALEASCELASKNGPYKTYPNSPTSKGLLQFDLWNVKPSNL------WDWNSLKTKIAQHGLRNSLVTVTSNTEVESTIFGNVNSIEPldtnvKRRYISLGESKPKEI-QVVNPYllKDLHDRKlwdeKLIPELVNNMGSIQ---------------------------------------------------------------------------------
>UniRef50_C8WWY9(26-771:772) Ribonucleoside-diphosphate reductase n=15 Tax=Firmicutes RepID=C8WWY9_ALIAD  E=0 s/c=1.29 id=31% cov=96%
--KTFTVEKRDGRIEPLSLDKIFAFLKRGCEAAEGCDPERLAADVWPQLRDGMRTSEIARVAIQAAVEKTSVAEPGWQFVAARLLLFDAYKQAsrnrgYRHLGYGDFYQLIVELERIGRYGTYIRQHYSEDEIAELAAYIKPERDYLFNYVGLKQLLDRYAIRNLDNG-IMELPQELFMGVSMHLAMKEK--DKVAWAKRFYDMLSTLQATVATPTLSNARKPFHQLSSCFIDMPEDDLVSIYATDEAFARVSKFGGGMGIYVGKIRARGSAIRNHPGASGGVVPWIRNFNNTAVSCNQLGMRAGAAAVYLDVWHKDILDFLQLRTNNGDERMKAHDIFPGVCIPDLFMRRVEERGMWYLFCPYEVRKVMGFSLEDswGEEFERRYEACVENPNLPRVEIPAIEIMKRIMQSAFETGTPFIFFRDTANRLNP-NKHAGMVYCSNLCTEIIQNMSPSRRIEeteeggiitmkTEAGDFVVCNLSSLNLGRCRDLDSIREIVRRQIRAMDNVIDLNHYPVPQAAVTNRKYRAVGLGVSGYHQYLAEKGIPWESEAHVKHADELFEWINFFAIEASMELAREKGPYPLFEGSDWQTGRY------FDLRGYRTRPGGPDWDGLRREVAEHGVRNAYLVAIAPTSSTSLIAGSTAGIDPVYARFFLEEKKNGVVPQTAPNLNDKTFWYYKEAHTIDQRWSIEACAARQRHVDQSQSFNLYITP------GISARQFLDLYLLAWKRGLKTVYYVRSK------------SVEVEDCVACS---
>UniRef50_P48591(12-765:812) Ribonucleoside-diphosphate reductase large subunit n=94 Tax=root RepID=RIR1_DROME  E=0 s/c=1.25 id=30% cov=93%
----LYVIKRDGRQEEVHFDKITSRIQKLCYNLNMDFVDPVTITLQVinGLYCGVTTQELDNLAAEIAAGLTC-NHPDYAILAARIAVSNLHKETKKAFSDvfEDLYNHVNKETNQKVpLVSEFHYNVVKKNATRLNSSIIYDRDFGYNYFGFKTLERSYLLKR--NGKIAERPQHMLMRVAIGIHG-----EDIDAAVETYNLLSERYFTHASPTLFAAATNRPQLSSCFLLTMtADSIEGIFKSVEQCAMISKSAGGIGLNVHCIRAKGTSICGTNGTSNGLVPMLRVFNNVARYVDQgGGKRPGAFAIYLEPWHSDVFEFLELKKNTGKEENRARDLFYALWIPDLFMKRVEANGDWSLMCPHKCPGLHDVW---GDEFEKLYEKYEQEGRANR-TVKAQSLWFAIIEAQVETGNPYMLFKDACNRKSN-QQNVGTIKCSNLCTEIVEYSAP--------DEIAVCNLASIALNMFvtpektYDFKKLKEVTKIVTKNLNKIIDINYYPLPEARKSNLRHRPVGIGIQGFADALILMRFPYESEEAGLLNQQIFETIYYGALEASCELAQTEGPYETYEGSPVSKGILQYDMWDKVPTNL------WDWQKLKESIRMHGVRNSLLVAPMPTASTAQIMGNNESFEPYTTNIYTRRVLSGEFqvvnhhllrdlteldlwdddmknqiissrgsiQNIETIPPKVRDLYKTVWEI-SVKSTIKMAADRGAFIDQSQSFNIHVAEPNY-------GKLTSIHFYSWKAGLKTgMYYLRTKPAANAIQFT-----------------
>UniRef50_D1BPH5(3-759:760) Ribonucleoside-diphosphate reductase n=3 Tax=Veillonella RepID=D1BPH5_VEIPT  E=0 s/c=1.15 id=29% cov=95%
----IMIKKRDGHFEPLSVEKTKRMIAFACLGLDSCDPLELEMDAKLQFVDGMTTKEIQKTLVQTAIEKviskkddgfgnqVNKMNQDWQFVAARLFLFDLYKEAaitrrYKAFGYGNFPNLVNMLVEEKKYADFFVTEYTADELQELGDYIKPKRDYLFNYEGLKLLADRYLVKG-FNKEIFELPQERFMAIAMHLALVEGK-NKVKYAKKFYDLMSQLKMTTATPTLANAGTPFHQLSSCFISGVDDNLWSIYDVNSKFSRVSKHGGALGIYLGKVRALNSDIRGFKNSSGGVIPWIRLYNDTAVAVDQLGKRKGGATVTLDIWHKDFYEFVELRTNNGDDRRKAHDIFPAISVPNIFMERMLARENFTLFDPHEILAVKGYSLEnyfdtdDKKEFTKRYIECEQDPNLHGIEVPALDMMKKIMRSAVETGTPFIFFRDTVNAANP-NKHAGMIYASNLCHEIAQNVGFTNLAEeiinedgtittkTNTGDMVTCNLNSISLGRITD-EELEENIALQIRMLDNVISINQAPVPESRMTSDKYRAIGLGTSGYHHYLVNHDIQWESDEHIEVADKLFENIAFYAIKASMELAKEKGAYPAFKGSEWETG-----EYFTRRGYTSDR-----WKQLAADVAKYGIRNGYLMAVAPTGSTSNIANTTAGIDPIFKKFFIEEKKGSFTPKTAPDLNDKTFWLYKEAHTIDQQWSIKACGVRQRHIDQAQSFNLYITP------QMKAKEILDLYVEAYKQGIKTIYYIRNQ------------SLEMDECTSCS---
>UniRef50_A9KRT3(2-763:764) Ribonucleoside-diphosphate reductase n=2 Tax=Clostridiales RepID=A9KRT3_CLOPH  E=0 s/c=1.14 id=29% cov=95%
---DIMIKKRNQTYEPLCVEKTKRMIAFACEGLEGCDPIELELDARIQFVDGMSTKEIQKMLVQTAIEKVIHTKKDefgnimrethtnWQYVAARLFVFDLYKEAaierhYKHFGYGDFLNLVNSLVEEELYGSYLTDAYTQLEIKELGAYIKPERDYLFNYEGVKLLSDRYLVKG-LKKEVFELPQERFMVIAMHLAIPEEKAKRMEYAKKFYDLLSSLQMTVATPTLANAGTPFYQLSSCFISVVGDNLWSIYDVNQKFSSVSKHGGALGIYVGKIRALNSEIRGNKNASGGVIPWVRLYNDTAIAVDQLGRRKGGATITLDIWHADLYDFLDLKTNNGDDRRKAHDIFTALSVPNLFMERLERREEWSLFDPYLVNKVMGFSLEDSYdevaenEFTKRYLACEECKELPRITVPALEVMKRIMKSAVETGAPFIFFRDTVNQANP-NKHAGMIYSSNLCQEITQNMSESELREEliqdesgakviitkiKPGDMVTCNLNSISLGRIEKKD-LAVNIPLQIRMLDNVITLNQTPVAEARITSDKYRAIGLGTSGYHHYLVNHGIGWETQKHLEEADDLFEEIAYQAIKASMELAKEKGKYEAFHGSEWETG-----EYFKRRDYTSDR-----WLALSKEVAEHGMRNGYITAVAPTGSTSNIANTSAGIDPIFKRYFIEEKKGSFIPKTAPDLNTSNFWLYKEAHTIDQQFSIRACGIRQRHIDQSQSFNLYITP------EYKAIDILNLYMEAWRKGLKTIYYVRNQ------------SLEMDECTSCS---
>UniRef50_O83972(133-834:845) Ribonucleoside-diphosphate reductase subunit alpha n=48 Tax=Bacteria RepID=RIR1_TREPA  E=0 s/c=1.15 id=27% cov=87%
----------------------------------------------------------MQLLIKAAVELTAQEAPQWELIAARLLMLDFSlalGTSLEKLNIHSFYEKITYLEEAGLYGVYIRTHYSRAEIEEAATYLECSRDKLFTYSSLDMILRRYVIRTRAH-VPLETPQEMFLGIALHLAMNET-QDRMQWVKRFYTVLSKLQVTVATPTLSNARKPFHQLSSCFVDTVPDSLDGIYRSIDNFSQVSKFGGGMGLYFGKVRAVGAPIRGFQGAAGGILRWIKLANDTAVAVDQLGVRQGSVAVYLDVWHKDIPEFLQLRTNNGDDRMKAHDVFPAVCYPDLFWKTVRDNlgASWYLMCPHEILTVKGYALEDfyAEEWEKRYWDCVKDARISKRTIPIKELVRLVLKSVVETGTPFAFYRDHANRANP-NGHRGIIYCSNLCTEIAQNMSAINLVSvkitevdgqkvvvqtTRPGDFVVCNLASLVLSNIDlsDDKELREVVRVAVRALDNVIDLTYYPVPYAQVTNAYYRAIGLGVSGYHHVLAQQGIDWESDEHLAFADRIFERINRAAIEASMTIAREKGAYGCFTGSDWCTG-----AYFRKRGYVSE-----DWQRLQREVATHGMRNGYLLAVAPTSSTSIIAGTTAGVDPIMKQYFLEEKKGMLMPRVAPSLsQKTCPLYKSA-HAVEQRWSIRAAGLRQRHIDQAQSVNLYI------TTDFTLKQVLDLYVYAWEVGMKSLYYVRSQS-------------------------
>UniRef50_C8XUI7(2-759:759) NrdA ribonucleoside-diphosphate reductase alpha subunit n=1 Tax=Shigella phage phiSboM-AG3 RepID=C8XUI7_9CAUD  E=0 s/c=1.05 id=49% cov=96%
------VIKRDGSSVPFDIEKPHEVVDRACDGLTGVSMSEVIAASKIQFTDNMRTDRIQDILIQAAASLISVDKPNYQYVAARLKSYDLRKAVYGQYKPPHLLDIFVKNIKQRVYDREFLDLYTTEEFNELNDVINHKRDKNFTWAAMGQLTEKYLLRDRSKKDskiFYETPQVMYMGIAMALFSNWDKDSRLEMVKKFYEYASTGKFSLPTPIMAGVRTPTRQFSSCVLIKTGDTLDSINATAKTIVDYVSKRAGIGFDVGAIRGIGSPIRGGEMVHTGLIPFIKYLTGALKSCSQGGIRGGAATAYIPLWHYQFDDVVVLKNNRGTEENRERRIDYGIQINRVMFERLVAKQPLYLFDPKDNREMYEAYFADVDKFRTLYEnmiKAADAGLVRSKKLQAEEVFQMLLDQRSDTGRIYIAFVDHMNEYSPFN--LDTIYSSNLCLEIALPTREFEQYNDENGRVALCTLASFNLTAFEDPTEMEDVAFVLVSALDMLLEYQDYPAIQARKAVEDYRPLGVGIVNVAHFLAKNFTGYGSPAGLEMLDAWMAHLHFYLVKASNRLAMKFGACK--RGTIHGMGQVTADLQPLPLDILPNGKKPEgmayglDWDDLKDDLKTYGIRNATLLAVAPTESSSQVLNATNGIEPPKGLVSIKGSKDGTYKQVVPDVETLGPLYDLKWDLDCIE-YLKTAAVIQRWVDQSISTNTWYDPEKYPDGKIPRAKMMQDILSFYMWGGKTLYYNTNKDAKEDEE-------------------
>UniRef50_A7KUZ9(55-755:767) Nrd alpha subunit n=2 Tax=root RepID=A7KUZ9_9CAUD   E=0 s/c=1.03 id=27% cov=86%
-----------------------------------------------------------------ALNNIDMGAPDWTFVAANMKLQQMYKTASEnrgysrSLKYGSFYKLIKTLTEMGIYSPAILASYSEEEINEIGRMIDPSKDSLFNFIGLFLLNDRYAATD-YQGSLYELPQERLMMIAVTTMINEPKATRLAHIKELYWALSNLYATAATPTFANAGKSYGQLSSCFIDKVDDSLDGIYLSNMDAARLSKDGGGVALYFSKVRALGSPIKGFEGKSSGTTPWIKMFNQTAITVDQLGQRKGAFAIYMCLDHKDIMKFLELGLNNGDEADRAREIFTGVAVPDLFMKKldeVDENgrsiGQWHTFCPHQIKQhmqwkdengnlltLDDFYDEkDTKYYEEKYMEAVNNPLLPRDTHRAMDIMVRIMEIQLETGMPYMFYRDQVNRMNPNKHVHGIgrtaIYCSNLCTEIAQNqvsSMIIGEYIDENenihmvrspGEYVVCNLASVNLAKAVPAGVLARVIRIVTRMLDNIIDINTISVLQAGITNKRYRPIGMGAYGWHHLLAILGLDWESEAAVNYADTLYEEFAYHVIDSSVELAKEKGTYKYFEGSAWHTG-----EYFDQRDYVSAK-----WKALKEKVAKFGVRNGWMMALAPNATTAKVGGSTDGNDPITAVEGAEEKGNFKFKVTAPGLDHnTYNVYRKTRHHIDQLWSVKQTAKKQRHIDQSISFNLYVA------SDIDGAELLNIHKTAHKLGIKTTYYVK----------------------------
>UniRef50_O12935(23-751:770) Ribonucleoside-diphosphate reductase n=1 Tax=Spodoptera exigua MNPV RepID=O12935_9ABAC  E=0 s/c=0.98 id=26% cov=90%
-------------------ENLTLLLNSLCKNIDTryVDVPKLVHKVVAESGD-IGFDKIKLYCADVAASM-TYVHYDYALLAGRILVEDLHSKVSSCF-VTIANDLFSRNVLSDEFNQ-----LVKKHGAILNNEIKHERDYNYKYFGFKTLTNGYLLK--IDDVIMERPQHMLMRVALAIHGD-----DVKSVIETYQLMSLGTFTHASPTLFSAGTRRQQMCSCFLQSIkDDSVDGIYKTLHESALISNLGGGLGLSAQN--SGGS----------GLVNMLRVFNNMVRHVDQGGKRKGALAAYIEPWHPEIYEFLNLRRNMGSEDTKARDLMLGLWIPDLFMKRVKNNQMWSLFSHKTCPDLADKYGFD---FEMRYCDYENAQVYERQ-VKARDLFRFIVETNVETGGPYMLYKDHCNNFSN-QKNLGTIKCSNLCAEIVQY--------CDENETAVCNLASIAVNKCVDVDAktfdyvlLKHLTKIIVRNLNKIIDVNHYPTAESERSNKKHRPIGVGIQGLADAFVLLDIAYDSDDARFVNYSIAETIYFAALEASCELAKINGPYESYTDSPVSRGILHFHNYDDENGVYHSNNL-WDWNELQCNINKYGVRNSLLVAYMPTATTAQILGNNESFEPFTSNVYLRRVLAGEFQVVNQYLvkalidldiytpelrnkilaengsvqnideipQHVKNLFKTAWEIKSK-CIINMAADRAPFIDQSQSLNLFVAEPTY-------SVVSSIHFYAWEKKLKTgMYYLRTKPAAQATKF----TVDVETVASCS---
>UniRef50_C1DPR2(145-442:1338) Ribonucleoside-diphosphate reductase n=14 Tax=cellular organisms RepID=C1DPR2_AZOVD  E=5e-83 s/c=1.05 id=26% cov=38%
-HPSIRVARADGVLVPLDMGRLDTIIGEACEGLAEVDAALIQKETLKNLYDGVAEKDVNTALVMTARTLVERE-PNYSYVTARLLMDTLRAEALGFLGVAESATHHEMadlyaralpvYVEKGIEFELLDPKLREFDLVRLGAALDHERDQQFTYLGLQTLYDRYFLHK--DGIRFELPQVFFMRVAMGLAIEEPQKE--ERAIEFYNLLSSFDYMASTPTLFNAGTLRPQLSSCYLTTVPDDLSGIYNAIHDNAMLSKFAGGLGNDWTPVRALGSYIKGTNGKSQGVVPFLKVVNDTAVAVNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1HSG6(50-685:697) Ribonucleoside-diphosphate reductase n=2 Tax=Bacillaceae RepID=B1HSG6_LYSSC  E=1e-154 s/c=0.86 id=24% cov=81%
-------------------------------------------------------------------------------------------------------EKIRYLVDEGYYEKAFIDMYEMDFIKKLYKKA-YDYNFRFpSFMSASKFYDSYAMKSRDGEEILEKYEDRIVIIALYLA-----QGNTVLAERSVEAMME-AYQPATPTALNSGkKARGELVSCFKLSMDDSMNSIAENIGYCLELSRLGGGVGVNLTDLRPLGDPIKEILNRASGVIPVAKLLENSFSYSNQLGQRNGSGVVYLNIFHADIENFISSKKPNADDKIRLATLSTGIIIPSIFFELMKRDKDIVLFSPYDIFKVYGKRMSEI-SISEMYYELLDNPKIRKiKRLNARRLYTEVKKAQFESGYPFEIFDDNVNDVHPL-KNIGRVKMSNLCTEIlqVQETSVITD-QDQPNEYGLdvsCNLGSIDIHAASKVNDFEALIDTAMHLLTNVSQMTHIKnVPSVAKANQLMHSVGLGCMNLHGHLVTEGIMYGSKDSIHFMDRFMEAMNYYSLKSSMEMAKEKAETFYrFEDSDYASGIY-FDQYVNKteeelspavLKALGNIPIITSkmWGLLKQDVMQYGLFHSYRLAIAPTGSISYIRSCTASISPCTERVEVRDYADS--RTIYPMPHLTNENSHLYVEAYDVDPYdlIDLYAASQKHVDQGISMTLYV------TDNWTTEQLAKVYIYAWVKGIKSVYYVRQR--------------------------
>UniRef50_C1DWR9(3-214:1222) Ribonucleoside-diphosphate reductase n=3 Tax=Hydrogenothermaceae RepID=C1DWR9_SULAA  E=3e-47 s/c=0.91 id=24% cov=27%
----RIVVKRDGSVEKFQMKKLVDAIFALLEGLELPDdyeiVFKVAKELDLKIPEKVTTEELDYLVLKAIEHLIPKNYI-YDTLATRQLLKIINRRIDRRFN--SFKDYINYAVEEKLLKPELLQ----FDIDRLEKSIDYSRDYNLDYFGLSTLKDRYLMKDR-DFETIEKPQWFFMRVAMGIGNTEDE------IIKIYNKLSNLEYLHSTPTLFNSGTLTNQYSSCF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P50620(50-699:700) Ribonucleoside-diphosphate reductase subunit alpha n=170 Tax=root RepID=RIR1_BACSU  E=1e-138 s/c=0.76 id=22% cov=83%
----------------------------------------------------------------------------------------------------NLKEKLDYLVENQYYEEEFLSLYSFEDIKEVFKTAYAKKFRFPSFMSAFKFYNDYALKTNDKKKILERYEDRISIVALFFA-----NGDTEKAKEYVNLMINQEYQPSTPTFLNAgRKRRGELVSCFLLEVNDSLNDISRAIDISMQLSKLGGGVSLNLSKLRAKGEAIKDVENATKGVVGVMKLLDNAFRYADQMGQRQGSGAAYLNIFHRDINDFLDTKKISADEDVRVKTLSIGVVIPDKFVELAREDKAAYVFYPHTIYKEYGQHMDEMD-MNEMYDKFVDNPRVKKEKINPRKLLEKLAMLRSESGYPYIMFQDNVNKVHANN-HISKVKFSNLCSEVLQASQVSSYTDyDEEDEIGLdisCNLGSLNILNVMEHKSIEKTVKLATDSLTHVSETTDIrNAPAVRRANKAMKSIGLGAMNLHGYLAQNGIAYESPEARDFANTFFMMVNFYSIQRSAEIAKEKGeTFDQYEGSTYATGEY-FDKYVstdfspkyEKIANLFEGmhiPTTEDWKKLKAFVAEHGMYHSYRLCIAPTGSISYVQSSTASVMPIMERIEERTYGNSKTYYPMPGLASNNWfFYKEAYDMDMFK-VVDMIATIQQHIDQGISFTLFLKDT------MTTRDLNRIDLYAHHRGIKTIYYARTKDTGQDSCLSCV---------------
>UniRef50_D2BQ84(46-720:722) Ribonucleoside-diphosphate reductase n=32 Tax=Lactobacillales RepID=D2BQ84_LACLK  E=1e-134 s/c=0.71 id=26% cov=84%
------------------------------------------------------------------------------------------------YEADTYIDKLNWLVKEEYLEAEFLEKYKPEFITNLRKEL-SKFEFHFDsFMAAYKFYNQYAMKNNDGSLYLEDFEDRVLMNALYMAdGDEKLANNLAFA------MINRRYQPATPTFLNAgRKRRGEFVSCFLLQLTDDMNSIGRTINSALQLSKNGGGVGLNLTNLRAAGAPIKGYDGVAAGVVPVMKLFEDAFSYANQLGQRQGAGVVYLSLFHPDIMEFLSTKKENADEKIRVKTLSLGVTVPDKFYELVKKGETMYLFEPYFVEKYYGKPFAEVD-ITAEYDKMVANPEIRKTPINSRELEQELSKLQQESGYPYIVNVDTVNQANPVD---GVISMSNLCSEILQVQTPSVLNDDQTykvvGTDVACNLGSTNvLNMMTSSNEFGTSIEAMVRALTFISETsNLDTVPTVRKGNDEMHAIGLGAMGLHSFLAQNQIHYDSKEAVEFTSVYFMLLNYYTLVASNKLAVEKGsSFKNFEKSAYADGSY-FDKYlthdyfaavsskVQELFKGIAVPTIEDWTALRDTVKTSGLYNSYRMAVAPNGSISYINDCSSSIHPIVNRIEERqEKKVGKIYYPAAGLAtETIPYYKSAYDTDM-RAVIDVYAAATEHVDQGLSLTLFMRSTlpeglyewKVANNKMTTRDLSILRNYAYKKGIKTIYYIRT---FTDDQEEVGAN----QCESC----
>UniRef50_A7IY07(756-1102:1103) Ribonucleoside-diphosphate reductase n=3 Tax=Chlorovirus RepID=A7IY07_PBCVN  E=3e-85 s/c=0.92 id=26% cov=39%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNEIVEYTS--------KEETAVCVIGSVVLKNYvkndkFDFDDLRKNVKILAKNLDRSIDVMAYPIKEAETSNKLRRPIGVGVQGLQDVFFKLRFSYDSPEARDLNREIFEHIYYAAVEASVELAEIHGPYPTFEGSPASKGILQYHLWDVTPKS------NLDWRGLEERVKK-GIRNSLVTALMPTASTAQICGSVEAFEPITSNLYSRRTLAGEFPVINSYLvreliergtwneqmknqiianggsiqkvigihPSVKAVYKTAWDLSMK-SVIDMASDRGAFVDQTQSMNLFLAQP-------TLKNVTSMLFYGWKSGLKTLqYYLRSKPASSAIAVTI-----DNDCLVCS---
>UniRef50_Q2N7C2(87-660:681) Ribonucleoside-diphosphate reductase n=90 Tax=root RepID=Q2N7C2_ERYLH  E=1e-121 s/c=0.76 id=28% cov=70%
--------------------------------------------------------------------------------------------------------------------------------------IDESRDVNLTEFGKETLIDRYLLPG-------EKFQDLFARVA------DAYADDQEHAQRLYDYISRLWFMPATPVLSNGGTNRGLPISCYLNSVSDSLDGIVGTWNENVWLASKGGGIGTYWGNVRGIGEPV-GLNGKTSGIIPFVRVMDSLTLAISQGSLRRGSAACYIDIHHPEIEEFLEIRKPSGDFNRKALNLHHGVLITDAFMEAVREGAEFDLKSP-------------------------KDGSVR-GTVDARSLFQKLVETRLATGEPYIVFADTVNRMMP-KHHRDLglkVSTSNLCSEITLPTGVDHL---GNDRTAVCCLSSLNLEKWDEWNGEKDFIEDVMRFLDNVlqdyIDRAPDEMARAKYSASRERSVGMGVMGFHSFLQSKNLPLEGPMAKAWNDKMFKQIHAKANEASMLLAKERGPCPDAEEMGAME------------------------------------RFSCKMAIAPTASISIICgGTSACIEPIPANIYTHKTLSGSFIVKNPYLekllkkkskdstavwnsilerggsvahldfltPEEKAVFKTSFEI-DQRYLLEFAADRAPYIDQAQSLNLFI------PADVDKWDLMMLHFQAWEKGIKSLYYLRSKSVQRA---GFAGGVEADNTKDAA---
>UniRef50_B1L7R7(6-793:876) Ribonucleoside-diphosphate reductase n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L7R7_KORCO  E=1e-111 s/c=0.52 id=25% cov=86%
------VVKRDGRVVEFDSFRIRRAIEMAMR--------------EVGKFDEAILDKVVKYVLDVIDSTFSDERPPHVEEIQDIVELALMK--YDLFEVAKAYIVYRKEREK----------IRKEKMAILGKDYVDDVDKRLSLNAVRLLASRYLQKGP-DGRFLEDPKGLFIRIAslvvipdilydplifdkegeqevhpteyfnpeewagkVGLGGGDPEnhlappfvwnahhlermkalydelnsqgKMRVSWSqffdmlrdgrfdhhykdfLEYYRLMVDLKFIPNSPTLFNAGTMLGQLSACFVLPIEDSLESIMRSATEAAMIFKSGGGVGINYSKLRPQGDIVRSTGGQASGPVSFMRIIDVITDVVKQGGRRRGANMGILEIWHPDIMKFIEAKAKPGN----LENFNLSVMITEDFWKYYEEGKDYPLINP-------------------------RNGEV-WGSIDPREAFRKIAEMAWRTGDPGVLFADNINRRNILREHLGEIKSTNPCGE--EPLYPYES----------CNLGSMNLYAyirrenglvTFDWDEYSRDIRKALRFLDNIIDVNKFPIPEIEKTTKRTRKVGLGLMGLADTLFALRIPYNSEEGFNFMRRAAEYLTYFAMLESVERAKERGSFPLFPESGYVRGEMPVEGF------YHPEIWNLDWDYLREQIMRNGIRNAEVTTIAPTGSISMIAEVSSGIEPQFALVFEKRVTVGSFFYVDAEFerqlkenglysekilrdiaenggslygieapegkedviERMKRIFLVAYDIPWWDH-IRAEAEISRWICAAVSKTINM------PNWVSVSDIEKAYLFAHRLGLKgiTVY----RDGSKSAQ-------------------
>UniRef50_C0QPQ0(5-765:847) Ribonucleoside-diphosphate reductase n=2 Tax=Hydrogenothermaceae RepID=C0QPQ0_PERMH  E=1e-111 s/c=0.53 id=24% cov=86%
------IRKRDGRIVPFNPEKITNAIWKAMQAVGEKDFStaekiskEVVRELERTLKPGeIPDvEQIQDIverkLIEAGLARVAKAYILYRQkraeirkekqqilnkkeidevdkrfdinalrvLAARYLNKDRAGKIIESPKQLFQRVAVNTALPSLLYDERV---YSKKELKKQPvEDFDPERyegklkigDYTLNRYHLEGLKRVY---DRLNNE-------RRMKIPFSKLLKMIEKGDFESygreIDQYYSIMVEKKFMPNTPVLVNFGNPLGMGMACFVLDMEDSIESIMETLKRAALIFKAGGGCGYNFSKLRPKGDFISTTHGKSSGPIAFMTLYDKMTDVIKQGGVRRGANMGILNSDHPDIEEFIVAKKGN----VQLTNFNISVFLKEDFWDYYRENKPYPLINP-------------------------RDGKV-WKYVNPRNLFDTIVYEGWESAEPGLLFDDNINRYNPFLETFGRIQATNPCGEVLLYPNES------------CDLGSINLWAFikeyydgngrkveVDWDGLEKTVRIATRFLDNVLDINKYPFKEIEKETLKNRKIGLGIMGLADFLFELEIPYNSEDGRRWMERVMEFVNYYSKEESIQLAKERGKFPSYNKSFYRKGKLPIRGFEEK------ESWNLDWDKLIDKIKKHGLRNAFTTVIAPTGSISMIAGTTSGIEPIFALVYEKKVTVGTFYYVDPVFEKTMEREgifddTLIKDVSKNEGSIqdikyipekwkkvfvtamdisaedhvKALASVQKWTDSSVSKTINF------PEDATVEDMKRAYLLAHYLGCKglTVY-------------------------------
>UniRef50_A9WCH6(19-603:822) Ribonucleoside-diphosphate reductase n=3 Tax=Chloroflexus RepID=A9WCH6_CHLAA  E=1e-103 s/c=0.65 id=23% cov=71%
------------------------------------------------------------------------------------------------------------------------------------------------------LKKRYLLKNE-HGDVIETPETMFWRVAETIAAvdaryGASAEQVEERAERFYHLMTQGYFEPNSPTLMNAGRPLGQLSACFVLPIDDNLTSIYETLKHQALIHQSGGGTGFSFSRLRPRNDVVRSTMGVASGPVSFMDVYNHSTEAIKQGGTRRGANMGILRCDHPDILEFITCKLDTT----KITNFNISVAITDAFMRAVERDEEYDLINPRT--GLGQIASRDGLKHPLTGEVLVPAGQPMR--LRARMVFDLIVQCAHATGEPGLFFIDRANEYNPV-PHLGEYEATNPCGE--QPLLAYD----------VCNLGSINLGKFVtdagtiDWESLRDVVHESTRFLDNVIDANHYPLEQITQLSQRIRRIGLGVMGWADMLVRLGIPYNSAQAIDLARQVMRFIDEESKVASEQLARERGPFPEWEYSIWG----PDATCARRPDGSRIRPQRL-------------LRNCNVTTVAPTGTISIIAGCSSGIEPLFAIAFWRYQADTRMLDINQDFvaqakregwysDELMERIadtghihhpevpasvQRVWvtaHDIAPEWHVRMQAAFQEYTDSAISKTINFPHEATPD------QVREAYELAFRLGCKgiTVY----RDGSRANQ-------------------
>UniRef50_B5YGJ2(11-542:584) Ribonucleoside-diphosphate reductase n=12 Tax=cellular organisms RepID=B5YGJ2_THEYD  E=1e-100 s/c=0.69 id=25% cov=65%
------------------------------------------------------------------------------------------------------------------------------------------------------LEIRYLLKNE-KGEPIENPEQLFQRVSSYIAQAEKiyKKNSFEWEEKFHELISSLRFLPNSPALMNAGKPKAQLAACFVLPIEDSIESIFKTLKDAALILQSGGGTGFNFSSLRPKGDVVRSTGGVASGPVSFMKIFDKASDIIKQGGARRGANMGVLRVDHPDIFEFIRIKRIES-----LSNFNISVAVTDSFMEALFKNDYFPLINPRT--------------------------KEVVRKVKAKDIFDEIVESAWETGDPGVIFIDTINRSNPT-PHIGQIDSTNPCGE--QPLLPYEA----------CILGSLNLSKYVkegkiDFERLEHDVKTATRFLDDAIDVTHYPVPEVEKMHKGNRKIGLGIMGWADCLVELGIPYNHKKALALAEQVMQFISEKSHKASQELAQERGVFPNFKGSVWEKKGIP-------------------------------MRNATTTTIAPTGTISIIADCSSGIEPYFLLAYKQRILDTEFEIINKYLIEiaqkqgfysedfinqlrqkgtlrgmkevplrIKRLFKTALEITPEEH-IQMQASFQKYTDNAVSKTINL------SQRTRKEDVARIFILAYKKGLK----------------------------------
>UniRef50_C1A6X4(22-596:859) Ribonucleoside-diphosphate reductase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A6X4_GEMAT  E=1e-99 s/c=0.64 id=23% cov=70%
------------------------------------------------------------------------------------------------------------------------------------------------------LEKRYLVKDK-SGKPVEKPEDMFWRVATTVAEADRRYGASDgavqaIAEEFYFLMTQRRFEPNSPTLMNAGRPLGQLSACFVLPVDDALsngqSGIYDTLRSMALIHQSGGGTGFSFSRLRSRGSMVRSTTGVASGPVSFMQLYDASTDAVKQGGTRRGANMGILRVDHPDVMEFIACK----EDLTKITNFNISVGITTKFMDAVKADANYDLVDPVS--------------------------KKVTGELRAREVWDKMILGAWRTGEPGVFFIDEANRYNPV-PHLGDYEATNPCGE--QPLLAYD----------VCNLGSVNVGHyvsngVVDWEAMRRDIALSTHFLDNIIDVNKYPLPEIDALSKRIRRIGLGVMGFADMLVRLGIPYDSAEGVEMGRKVMEFLDVEGKKESERLARERGAFPEWAQSIWG----PDETCARDANGQRIRPMQL-------------LRNCNVTTVAPTGTISIIAGCSSGLEPLFAVAFMRNQAGVMMPDVNEDFvaiakaegwysDELMERiaktgsvqhaevpakWQSVFNTANNispEYHIRMQAAYQLHCDSAISKTTNF------GFAATVDDVRAIYEMAYEMKCKgvTVY----RDGSRDNQVLSTGATQD----------
>UniRef50_B5Y7X0(9-568:796) Ribonucleoside-diphosphate reductase n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y7X0_COPPD  E=2e-98 s/c=0.65 id=24% cov=66%
--------------------------------------------------------------------------------------------------------------------------------------------------ALRVLEQRYLLRDE-NGNIVETPEQLMHRVAHGLAQIETVWGATSEQIssveqDFFDILWKRDFLPNTPTLFHAGLPkdpkyrgRRFMSACIVLPIEDSIDGIFKTLWDAAKIMQAGGGVGYAFSRLRPKGSLVKSSGGKSSGPVSFMHIYDVMVDVVAQGGKRRGAQMGVLNVHHPDILEFIDAKKENTSGQGPLHNFNISVAVTEEFVQAYKEDTTFKLVAPHT-GEVVG-------------------------ELNAREVMHKIAENAWRTGDPGIIFIDRINQLDYLDD--GRIEATNPCGE--QPLPPYGS----------CNLGSINLKHMLkktdsgyqwDWEKFQRTIRLAVRFLDNVIEANDYPIPELEDYAKKARRIGLGVMGWADALSLLGIPYDSEEALEEARKVGAFLKEKSHLASQELAQERGVFEFYDQSKWKELGIP-------------------------------MRNAAVTTIAPTGTLSILANVNSGIEPYFALAFERKITAGTFHEVQPtlldvlkerelyseelvqriienegklrdledLPEDIRNAFPTAMEV-APEWHVRMQAAWQENIDSSISKTVNLPYQS------TVEDIENIYLLAYELGTKsiTVY-------------------------------
>UniRef50_B6YVI2(6-771:910) Ribonucleoside-diphosphate reductase n=1 Tax=Thermococcus onnurineus NA1 RepID=B6YVI2_THEON  E=6e-97 s/c=0.47 id=24% cov=85%
------VMKRDGRIVPFDKERIKWAIQRAM--------------LEVGVRDEKLLNRVVRRVVKRVNELYDGQVPHIENIQDIVELELMRVGLFDVAKAYILYRKKK-------------AEIREEKKKILNKDKLDEIDKRFSINALRVLASRYLIRNE-KGEIIESPRELFERVAtlvvipdllydervfdregnheqdlsnvekymekldeydrklsigrfklnkyhferllnlyrelaqkgqmkvsidevIGMLENGAFDKYEDEIEEYFRLMTSQTFMPNTPALINSGRPLGMLSACFVVPIEDDMESIMKAAHDVAMIQKMGGGTGLNFSKLRPEGDLVGTTTGAASGPVSFMHLIDAVSDVIKQGGVRRGANMGILEVWHPDIEKFIHAKeKNIGTNVLANFNISVGIW-SD-FWEALREGKRYPLINPRTGEKV--------------------------KEIDPKSLFEELAFMAWAKADPGVIFFDVINRRNVLEPAKGeKIRATNPCGEEPLY------------EYESCNLASINLAKFvkydeegkpyFDWDEYAYVIQKVAKYLDNAIDVNKFPLPEIDYNTKLTRRIGVGMMGLADALFKLGIAYNSKEGYDFMRKATEYLTFYAYKYSVEAAKKRGPFPLYEKTRYKDGELPVEGY------YHREVWTLPWDELVEEIKKYGVRNGMVTTCPPTGSVSMIADTSSGIEPIFALVYKKSVTVGEFYYVDPVFEaELKkrglWSDELLRKISDNYGSVQgleeipedmqrvfvtsmdihwldhilAQANIQLWLTDSASKTINM------PNDATVEDVKAAYLLAYKLGCKgiTVY-------------------------------
>UniRef50_Q67KQ2(1-577:776) Ribonucleoside-diphosphate reductase n=1 Tax=Symbiobacterium thermophilum RepID=Q67KQ2_SYMTH  E=1e-96 s/c=0.62 id=23% cov=67%
-------------------------------------------------------------------------------------------------------------------------------------------------------EKRYLRMKEDGTR--ETPDEMLRRVARVIAAVEEKygasKKEIRAVEErFYQLMDRQDFMPNSPTFTGAGTALGQLSACFVLPVGDSLPEIYETMKQAALIHQTGGGTGFAFSRLRPAGDVVRSSQGVASGPVSFLRVYNASTEAIKQGGTRRGANMGILRVDHPDILQFIESKA----DITQITNFNISVAITDAFMEALEKGTEYELINP-------------------------RNGEVTGK-LSAKLVWDKLVENAWKTGEPGIVFIDRINRRNPNN-HVEVIEATNPCGE--QPLPPYGS----------CNLGSINLANFvknpytdraeVDWERLGEVARTATRFLDNVIDANKYPLPQIAEKALRDRRIGLGIMGWAEMLVQMGLPYDSEEAVALGNRVMTFIKQKALEESMALAEVRGPYPEWEGSQWHK------------------------AGLK-------VRNATLTTVAPTGTISLFAArpdlpCSGGIEPKFALVFTRNQAGalmldvdgqfasiarregwysdelmqqvadrGTARGVSGVPEKWQRIFATSHDI-TPEWHVRMQAAFQGGdglpVDQ-QPVDAAVSKTINFPHHATVEDVGKSYALAWQLGLKgiTVY----RDGSRASQ-------------------
>UniRef50_A3EPA5(7-563:732) Ribonucleoside-diphosphate reductase n=3 Tax=Leptospirillum RepID=A3EPA5_9BACT  E=5e-96 s/c=0.64 id=25% cov=67%
--------------------------------------------------------------------------------------------------------------------------------------------------ALKVLEKRYLGKDEA-GIVRENPEQMFRRIADAIAsSNSQSSEREFLAEEYYRFMASLDFLPNSPTIMNAGRPLGQLSACFVLPVGDSMPEIFDTVKATALIHQTGGGTGFSFSRLRPKGAVVRSTGGQASGPVSFMKVINASTDAIKQGGTRRGANMGILRVDHPDILEFIDCKM----DLTQVTNFNISVAITDVFMQAVKEDGEYDLIAPH-------------------------NGEVV-GRLRAREVFDKIAHNAWANGEPGLFFIDTANRANPT-PSRWTYEATNPCGEQVL------------GPYESCNLGSINLERHvrssatgkpeVDWERLGRSVYLAVRFLDNVVDANRFPIPELAAVNQGTRRIGLGIMGFARLLMRLEIPYDSEEGLEMAEKVMSFIRDEAERTSQDLAKVHGPFPYYEGIGTRK------------------------------------RNSHLLTIAPTGTISMIADTSSGCEPEFSIIWYKNVMDGThLPYTLEMFEivarregfwsdglaekivQNHGSCRGLSEVPEKwqkvfatahdiapRWHVRMQAAFQKYIDAAVSKTINL------PQEATVEDVEDAYLLSFELGCKgiTVY----RDGSRHNQ-------------------
>UniRef50_B2A494(11-561:752) Ribonucleoside-diphosphate reductase n=16 Tax=cellular organisms RepID=B2A494_NATTJ  E=1e-94 s/c=0.64 id=24% cov=67%
------------------------------------------------------------------------------------------------------------------------------------------------------LEKRYL-KTNEKGET-ENPEDMLKRVADNIAQVEKdvyqkdKQEVSKVSQNFFDLMDNQYFMPNSPTLMNAGRELQQLAACFVLPIEDSMESIFEAIKNAALIHKSGGGTGFSFSNLRPKNDIVLSTGGVASGPVSFMKVFNSATEAVKQGGTRRGANMGILRVDHPDIQEFITCKR----DSDEINNFNISVGITEEFMEAVKQDGEYSLKNP-------------------------KNGQAVK-TLRAREVFDKIVEMAWGNGEPGIVFIDKMNENNPT-PHIGEIESTNPCGE--QPLLPFES----------CNLGSVNLSKMvnngaVDYQLLKETVHTAVHFLDNVIDANRYPLPEIEKTSKENRKIGLGVMGFGDMLFKLRIPYNSQEALDLAEKVMGYIDQESKAKSQELAKERGAFPNFKGSIY--------------DQKGEEP----------------IRNATTTTIAPTGTISILCGTSSGIEPLFALAFTRNVLDndklvevnpvfkeateeagcysselmekvadkGSIQDIDEIPDSIKKVFVTSHDISP-EWHLKMQAAFQKATDNAVSKTVNL------PNEADLKDVYEIYNLAHELNCKgvTVY----RDGSRDTQ-------------------
>UniRef50_A7I485(9-552:741) Ribonucleoside-diphosphate reductase n=6 Tax=Methanomicrobia RepID=A7I485_METB6  E=2e-94 s/c=0.64 id=24% cov=64%
-----------------------------------------------------------------------------------------------------------------------------------------------------ILSARYLRKGEKDFTDICR------RVASALADDENERAR------FYEAMISLRFLPNSPTLMNAGTEIGQLSACFTLPVPDTIDGIFDAMKEGAIIHKTGGGTGYNFSHIRPEGSPVQSTDGVASGPISFMRVFNAATDVIKQGGRRRGANMGILNVWHPDILAFISAKKKEGE----FSNFNISVMVNDKFMDLVAA-----------------------KSFETVWLT--KGGTGEKITVG--QIWNGIVEGIWKNGEPGILFYDEINRHNPT-PQLGEIDTTNPCGE--QPLLPYES----------CVLGSINLAAcvregAFDEDLLRDTSRMATRFLDLVIEKNVFPIPQIAEATRKTRKIGLGVMGVHDAMLMLGLSYDSEKGRAWCEWVMKVITETAIEESHRLAEKLGTFPAWQGSIW---------------------------------KDYEVRNAAMTTVAPTGTISLLAGCSSGIEPIFSFAYTRKNTVGKVFVIVNPVfkeallhtltgmgyagderekkagevishvhetgsmqdvawlsAEFRGLFKTALDIPWREHIL-MQACFQKYVHASISKTINM------PGSATKDDCAEALLMAWKLGLKgiTIY-------------------------------
>UniRef50_A9A645(13-781:884) Ribonucleoside-diphosphate reductase n=10 Tax=cellular organisms RepID=A9A645_NITMS  E=4e-92 s/c=0.44 id=25% cov=87%
------IRKRSGAVTAFNKDKISNAIykalaatSKADRGLADQLADNVVNKLVEQGFTSTrspTVEDIQDivesTLIDSGNSDIAKAYIVYRHerrklrdekmkvlnlkaldpvskkfdlnclrvLASRYLFRNGKNEIIE--SPTQMFERVAILVGIGdlMYDAQVFDKSgnTKQDVEEAKSYLekldafDYKfkvGDYFFNKWHFRSLINHYVTLANKGH----------MKISfkelLTLLAAKKLDGYADKITEYFDLMVSQDFLPNSPTMMNAGGRLGQLSACFVLGMQDGMEEIMKSTSDAALIFKSGGGVGINYSDLREEGDIVASTSGVASGPVSFMNIINTVTEVVKQGGKRRGANMGIIEAWHPDVEKFITNKTEPGVLEN--FNVSVGVW--EDFWHALVNtsDGNYVLRSPRD--------------------------KKPVKEINAHQLIDLIALSAWKSAEPGLIFFDQINKYNVFAKARqAPLRATNPCGEQSLYPYES------------CNLGSINLVNLvkrqadgtyeFDWQRYEETIRKTTRFLDNIIDVNHYPVPEINVASKESRRIGLGVMGVADLLYKLRIPYNSKEGYELQSKLSEALTYYSMEESVALAKSRGEFPLCSKTEYPEGKIPVAGYYEK----PKESHSYEWDALVEKIKQYGIRNVLTTTVAPTGTLSMIADCSNGMEPAFALVFEKRVTVGRFFYTNKIVEQVlkeNNLYndEILAKIADNYGSLKGIDEIpqwmqdvfvtamdihwsdhlmaqgvwQDWIGNAIAKTINMPY------DVTAEDVKSAYLLAHEIGLKgiTVY-------------------------------
>UniRef50_C1D7Z3(37-575:947) Ribonucleoside-diphosphate reductase n=5 Tax=Betaproteobacteria RepID=C1D7Z3_LARHH  E=3e-91 s/c=0.63 id=25% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVAAALAGQEQEPSR--HAESFYWAMEQG-FIPGGRINSAAGTeLSATLINCFVQPVGDSVSetrdgkvGIYEALLQAAETMRRGGGVGYNFTRIRPKGARVKGTNSRASGPVSYMRVFDRSCETVESAGARRGAQMGVLDCDHPDIESFIHAKD-AGD----LRNFNISVGVSDAFMQAVEADGSW---------ELVHKEEPDRKEFPDACQR--ADGKWVYRAVRARDLWNQIMESTYDHAEPGVLFMSKINRDNNL-SYCEVIESTNPCGEQPLP------------DYGCCDLGSINLTRFvrdpftakagFDFATFDKVVRQSVRMLDNVLDLTVWPLPEQQREAQSKRRIGLGFTGLGDALIMLTIKYSSDAGRAFAARVSEAMRNSAYDASVDLAIEKGAFPLFD----------ADQYLAEPHCASRLP-----KEIKARIKKHGIRNSHLLSIAPTGTISLAFadNASNGIEPPFSWFYTRKKrmADGtqqeyrvedhayrVYRELGGDVSSLPDYFVSALEMSALDHM-SMVAAVAPFIDTAISKTVNV------PADYPFADFESLYIEAWRAGLKgiTTY-------------------------------
>UniRef50_O41962(13-751:783) Ribonucleoside-diphosphate reductase n=3 Tax=Murid herpesvirus 4 RepID=O41962_MHV68  E=1e-88 s/c=0.45 id=22% cov=76%
------------------------------------------------------------------------------------------------------------------------------------------------YLAAARFYDTYVLRNDVK---YESVPHMFMRISafcayhciqneclfktlkhMELDRGNVVENAMDLITYFFEMIASQQVCCATPVMRSAGLRDANLSSCFIFAPAlDSEEKtVDAVFSELTKLLACKSGVGMDLS------TYSHGKNLHA-----VLKALDGQITYFNDHNIRPVSVAAYMEIWHTNIMDFLTAKLPENPE--RCGNLFQGVCIPEIFFRTYKNDpeSNWYLFDPKKAEVLTNTY---GYMFSIAYAGLVEQGAYE-AVVPIKSVMFALVSCIIKTGGPYILNKKAINRHDWHEwstHQYRAINCANLCAEVIQY----------PGEnVSTCNLANICLPKCleddkfvsgksclltyereFSIERLERATEAAVFIINACIHGGTLPTQRARRG-QSDRSMGIGVQGLADTFAMMGLGYFDAGSEILDQKIAETLYFNALNTSINFVKiGKGePYANYEQSKHSIGVLHWHDWDMCSPMVY---TRDEWEDLARSCEVHGVYNSQFVAYMPTAGTGQITGYSDSFYPFYSSMSSKVSNKEEILRpnmtlmsrmsdsevqtlrecnwdIAKLPEPLLQKYRIFLSAFDYEPslYVRRAMLRAPFIDQSQSMTLFLNE----DYASSASNIKNLLMYGWECGLKTlMYYCRIRKTATSNEFECVRRNSQQkyvNCADG----
>UniRef50_Q160T8(16-572:832) Ribonucleoside-diphosphate reductase n=25 Tax=Alphaproteobacteria RepID=Q160T8_ROSDO  E=9e-88 s/c=0.59 id=26% cov=62%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WEEKFYAALEDFKYLPAGRITAGAGTARSvTLFNCFVMgTVPDSMGGIFDMLKEAALTMQQGGGIGYDFSTIRPKGADVKGVAADASGPLSFMDVWDAMCRTIMSAGSRRGAMMATMRCDHPDVEDFIAAK----SDPARLRMFNMSVLITDPFMEAVKADGPWDLV------------------FDGK----------VYRTVQARDLWNRIMQATYDYAEPGVIFIDRINQANNL-SYCETIAATNPCGE--QPLPPYGA----------CLLGSINLARLVsnpfedtaalDEAALDDLVATAVRMMDNVVDASKFPLEAQAREAQAKRRIGLGVTGLADALLMMGLRYGSDEAARQTDRWLHSIARAAYLASVDLAREKGAFPLFDADKY----------------LASGTMQAMDEDVRDAVREHGIRNALLTSIAPTGTISLYAGNvSSGIEPVFAYAYTRKVlqKDGSrtEEEVVDYAVQLWREKFGDKELPDYFVnaqtlapleHVKMQAAAQKWVDSSISKTINC------PEDIGFDAFKDVYMEAWDSGCKgcTTY-------------------------------
>UniRef50_D0J9D2(28-558:571) Ribonucleoside-diphosphate reductase n=2 Tax=Blattabacterium RepID=D0J9D2_BLASP  E=6e-86 s/c=0.60 id=29% cov=59%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKFFNILWKGWLIPSTPVMVNLGTEKGLPISCFSGRVGDSMYEIYRKNLEMAILSKHGGGTSYDFSLIRSVGSPIKnGTLGTSDGIIPFVKSYDSAIIASKQGSTRRGAVAIYLNIEHQEYPEFLKIREPKGDINRQCHNVHQGVILSNSFMEKVLKK--------------------NGKE---------------------RSLWINTLKERVKTGEPYLFFKDNANRNLPENwkKNGLKIHHSNLCSEIMLPT--------DESHTLVCCLSSLNLYKYVEWKD-TQTVFYAILFLDAVLQefinkgKNIKGIEDAVRFAEKSRALGLGALGWHSYLQSEMIPFISVKSEILTHDIFGKIRSESQKATQYLAKEYG------ESEWNIGT--------------------------------GRRNLTLMAMAPNRSSAKLAGGlSQGVEPLAANIYVDDDAKGMHIRKNPYLEKilIKSGYNLpeVWEQIANEKgsclgltglsekeknvflcfkeinqleLIKQASIRQKYIDQGQSINLAF------HQNTPAKFINKVHLEAWKIGLKSLYYYRSES-------------------------
>UniRef50_B5IVI5(6-924:1042) Ribonucleoside-diphosphate reductase n=1 Tax=Thermococcus barophilus MP RepID=B5IVI5_9EURY  E=1e-85 s/c=0.35 id=24% cov=87%
------VMKRDGRIVPFDEGRIRWAIQRAMWEVGVRDeklLDKVVKDVVGRIN------ELYDGKI-----------PHIENIQDIVELELMRNGLFDVAKAYILYRKKK-------------AEIREEKKKILNKDKLDEIDKRFSINALRVLASRYLMKNE-EGKIIESPRELFERVAiLAVIPDLLYDDRVfskeggfaqdlkrvdyyrehldefdkklsigrfklnkyhferflslyqelaekgqmkvsideivkmledgafdkyeKEIEEYFRLMTNQIFMPNTPALINAGRPLGMLSACFVVPIEDDMESIMKAAHDVAMIQKMGGGTGVNFSKLRPEGDLVGTTTGAASGPVSFMHLIDAVSDVIKQGGVRRGANMGILEVWHPDIEKFIHAKeKNIGTNVLSNFNISVGIW--EDFWEALKEGRKYPLINPRTGKKV--------------------------REVDPKALFEELAYMAWAKADPGVVFFDVINRRNVLEKAKGQkIRATNPCvvgdtrilTEkgeieieklfelakeanidrlevldegalgeraekyayllpfkvIASNGKPVEAYVWKVGfkpsikivledgreltgdeehkvkvgdnyielknikvgdcievfkegckkvvevasvgnqlvytltmkevheyvansiisrncgeeplyEYESCNLASINLAKFvkyddegkpyFDWDEYAYVIQKVAKYLDNSIDVNKFPLPEIDYNTKLTRRIGVGMMGLADALFKLGIPYNSKEGFDFMRKATEYLTFYAYKYSVEAAKKRGTFPLYDKSDYPEGKLPVEGF------YHREIWNLPWDELAEEIKKYGVRNAMVTTCPPTGSVSMIADTSSGIEPIFALVYKKSVTVGEFYYVDPVFEaelKKRGLYsdELLAKISNNYGSVQgleeIPEDMQRvfvtamdvhWLDhilaQA-SIQLWLTDSASKTINMPndatVEDVKAAYLLAYKLGCKgvTVY-------------------------------
>UniRef50_B4W8S5(30-555:753) Ribonucleoside-diphosphate reductase n=2 Tax=Caulobacteraceae RepID=B4W8S5_9CAUL  E=1e-85 s/c=0.61 id=27% cov=65%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------WDRVAAALAEAEPTKTRARWRARFRETLDAYRFLPAGRILAGAGTGRAvTLFNCFVMGvVPDDLDGIFQHLREAAVTLQQGGGVGMDFSTVRPSGALVRGVGAEASGPLSFMDVWDSMCRTIMSAGQRRGAMMGCLRIDHPDIEAFIDAKR----DAVRFRNFNLSVLVPDAFMAALDADADWPLV-------------FDGE---------------IRRTVRATDLWTRLMQATYDAAEPGVIFIDRVNAANNL-AHCEVIAASNPCGEQMLPP------------YGACLLGSINLARLVsapfepdaalDEQKLADLTRTAVRMLDNVIDISRFPLPAQEAEARAKRRLGLGVTGLADALIFCGARYGEDRAVALTGRWLGLIRREAYRASAELAAEKGAFPLY------------DPAMLQRPNLASLDAET-----RELIGLHGLRNGCLTSIAPTGTTSLLAGNvSSGIEPVFAFAYTRKVMqpDGTRReEAVEDYALALWKTLKGPDAPldsapgdafvsaqtlTPEHHLRMQAAAQAQIDSSISKTINC------PENIDFEAFSDVYRQGYRMGCKglTTY-------------------------------
>UniRef50_Q66663(41-765:799) Ribonucleoside-diphosphate reductase n=8 Tax=root RepID=Q66663_EHV2   E=2e-85 s/c=0.44 id=23% cov=75%
---------------------------------------------------------------------------------------------------------------------------------------------------AKRMYDTYVLRTEEGggeGAVYESALQMYARMAAfftcqcfaypslrkTVSEVEGGSGRMESGLDffayFFKILASQLVSCATPVMRSAGLRQSYLASCFIMNPDMSTEDktLSAVFRDLSPLLCSKSGVGMNLTNFSSGGKNVQSC----------LRLINSQVEFCNDKNLRPVSVAAYMELWHEQIEEFLAAKLPENPE--RCQSIFQGVCVPGLFFRLYEQNPDsqWHLFSPKVGGHLAGLY---GDKFDEEYARLVRHGLYS-SSLPAKSLMFALISAIIKTGSPYILSKDAINRHHWFETQGNAISYANLCAEVVQQPHEF---------TSTCNLANVCLPACLRargegegagaagegegadrlspltpdlefcFDTLRAAVRAAVYMINASILGGVCPTPGVRVM-QAERSAGIGVQGLADVFAKLGRGYMDAESALLDARIFEVMYYQAVRASNQLVTVGGapPHANWKNSKLSRGEFHWESWGVQYDSLFIE--RQLWEELRESVTKHGTFNSQFIALMPTAGTSQLTGLSESFYPFYANVSSKVSNkeevmkpnitflervspsdvpllkyhGGDVSKLPPPLAAKYRNFLTAFDYSPEDQ-IRRAAARSPFVDQSQSFSFFLKEANVKSASYVKNLILLGHGLG----LKTiMYYCRIQ------KQTSLTALECLQCTESP---
>UniRef50_Q196Z5(4-602:630) Ribonucleoside-diphosphate reductase large subunit n=1 Tax=Invertebrate iridescent virus 3 RepID=RIR1_IIV3  E=1e-84 s/c=0.53 id=27% cov=69%
--------------------------------------------------------------------------------------------------------------------------------------IDESRNNLFDALGLQRLKDSYMKEDES------SPQERFAFIARQFCADDEP-----LAQRLYDYMSQHWLSPSSPQLSFGRTKQGLPIACFLPYLHDTARGLIDTWAEVSELSMIG--------GGIGLGVGIRQPDEKSVGIIPHLRTYDASCTAYKQGQTRRGSYAAYLDISHPEILSFLNTRRVGGDHNYKLLNLHNGVNVPDSFMKKI-----WILstlapfvkMDPcpttetlfkKAVTTLKDSrYFGADDRWlgEVSFAALAEQLDVvnrwdlidphtgkVKETIKATELWERIILTRAETGEPYIHWIDTSNRALPqFQKNLGLsIRQSNLCSEVVLPT--------DETRTAVCCLASLNLDYFDKWCNNEQFYLDVATYLDNVlqyfIDHAPPTLKRAVHSARSERAIGIGALGFHSYLQSKMVDIESLPAYLINKKIFKTISSHLERVNLELGELRGEAPDCVGT--------------------------------------GRRFSHMTAIAPNATSSIIMGNTsPSCEPFRANIYKQDTISGSFVTYNKHLKRLleeripdNQARERVWsSIKMHDGSVQhlnqltvqekkvfktwpeinqlslvmLAADRQKWIDQSQSTSLFFNPDERISY------VHKIHLKAWLHGLKTLYYFRSR--------------------------
>UniRef50_C4RH87(22-567:611) Ribonucleoside-diphosphate reductase n=1 Tax=Micromonospora sp. ATCC 39149 RepID=C4RH87_9ACTO  E=1e-84 s/c=0.58 id=26% cov=61%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WAARFRALMAENRFWPSGRILNNCGTRQGQLASCFVLPVEDDLGAIFDTLKLAASCHRTGGGTGFDLTPLRERGAPISTAEAAgSSGPVSWLHLFDAETGVVMQGGKMRGANLASLSVRHPDVFEFIDAKAVVG----RLANFNLSVTVDDAFMRTLIDGGEIDLVSP--------------------------VGGRPRRRVPAAEIWRRISAQAWRTGDPGLLFTDMINRANPLLDRLGPIRTTNPCGEQTLYPYEPS------------TLGSVNLRAMTgpdgrlDTARLERTVEDAVRLLDNSIDASHYPDPRITAMARGNRRLGLGVMGFADLLIALGVRYDSTRALAVVDEVGGRIRAVAEATTRRLAAERGTFPNF------------------------DPARFD----------APVRNCAVTTIAPTGTISMVAGCSSGIEPRFAPIWRKNVLvDGGVSYVdedlaadvcahggvdpeqarrlirerpvteLPMPEPVRDRYRYAHDVPG-EWHVRIAAQWQRHIDNAVSKTVNL------PRDCSVDDVAEVLTASWRLGCKgvSVY--RQGSREQDLQ-------------------
>UniRef50_C6P0N4(64-605:981) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Sideroxydans lithotrophicus ES-1 RepID=C6P0N4_9PROT  E=6e-84 s/c=0.58 id=23% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVARGLAQAETPEQRAKWEEAFF-LAQENGFVPAGRINSAAGlKIQATLINCFVQPVGDAISgtndgkpGIYDALQQAAETMRRGGGVGYDFSSIRPEGAHVKGTNSRASGPISYMRVFDRSCETVESAGARRGAQMGVLRCDHPDIEKFISAKDQ-GD----LRNFNISVGVTDALMQAVEKDEEFELVHSAEPSTAIKEAGATRRE----------DGKWIYRKVRATDLWKQIIASTYDHAEPGVLFIDLMNRDNNL-SYCEIIEATNPCAE--QPLPPY----------GCCCLGSIDLTRMvknpfskhagFDYEPFKQLVRVAVRMLDNVLDVTAWPLPEQQQEAKNKRRIGLGFTGLGDALVMMGLRYDTDAARAFASDITRIMRDEAYLASVDLAVERGKFP----------LLDADKYLSAPRFASRLP-----DEIKDKIRKHGIRNSHLLSIAPTGTISLAFadNASNGIEPAFSWFYTRKKrmMDGttkdypvedhawrVFKQQGGDVSHLPPSFVTALEISAIDHM-KMVAAVAPYIDTSISKTVNV------PADYPYEDFKDLYTEAWKAGLK----------------------------------
>UniRef50_Q6AJC4(74-622:785) Ribonucleoside-diphosphate reductase n=1 Tax=Desulfotalea psychrophila RepID=Q6AJC4_DESPS  E=1e-81 s/c=0.56 id=25% cov=61%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFTMIYQLDFLPNSPCLMNAGTEIGQLSACFVLPVEDSMDGIFTAIRNGALVHKTGGGTGYSFSRIRACNASVKSTHGVASGPLSFAAVFDAATETIKQGGKRRGANMGVLRVDHPDIMAFISAK----EDQDKFNNFNFSVAITDLFMAALEAD--------------------------KEYDLIEPSTGEVMGQLNAVEVFAKIVDLAWHNGEPGVLFIDAANR-DNTTPQLGDFEATNPCGE--QWLLPYES----------CNLGSINLGNFVKNDEvdysrLGQIVKTATCFLDNVIDCNVFPIPEIGEMTLKTRKIGLGIMGLHDLLIQLAIPYGSEEGRLLAAEVMQFIRDRCEEQSRKLAEEKGAFPAYD--------AEINLYPAR-------------------------RNAALTSIQPTGTVSMIADCASGCEPYFSIVMMKHVMDGDRLLMVNkhfekiareqgfysddlmvkvaesgtvvghaeIPEKWQEAFRTAQDISPEDH-IRMQAILQNSgVDSSISKTINLPKTA------TREDVKYSYISGYKLGCKglTVY----RDGSRDDQ-------------------
>UniRef50_D2EFV5(20-576:756) Ribonucleoside-diphosphate reductase n=1 Tax=Candidatus Parvarchaeum acidiphilum ARMAN-4 RepID=D2EFV5_9EURY  E=3e-80 s/c=0.54 id=24% cov=68%
----------------------------------------------------------------------------------------------------------------------------------------------------RIFYEKYSLSDLEGNRTEKTPIEMWKRISRELASVEKDDKKKDIENNFYRLLEDFKFVPGGRILFGAGANHkATLLNChHLPITKDSLEAIHDTAKEMARTYSYGGGVGIDISIVRPERS--------SSGImqqdfrlasVSFMKLYSITTGIIGQTGRR-GAWMITLDVTHPDIESFVTIKK----DKKSVRYANISVKVYDDFMDAVENDKIFTL-----------HFKNEKVEF--------------KKEIKALDLWKKRIDTAVNTGDPGIMFWDRMKSESPTEYDEKMaIKGTNPCSE-----QPLENY-------GACDLGAINLDYFvknqctdkaeVDWENLDKTVRYGVRFLDNVLDysYNRHALKEQADETVYARRIGLGIMGLANMLISMNLRYDSDKAIEFVDSLMKKIKETAYDESSNLAVEKGSFPAF----VAEKHLQRNFVKRLD------------KKLLDKISKNGLRNACILTVAPTGSISSMAGVSGGIEPICALSYTRRSESlseGKFEVLDPFVKRYMDKFKirdksTLPELfvtahkIDPFFRVKMQATIQKHIDSSISSTVNL------SADTDAETVDKIYRYAWKLGCKsiTVYREGSKDD------------------------
>UniRef50_B1HS20(132-805:866) Ribonucleoside-diphosphate reductase n=28 Tax=Bacteria RepID=B1HS20_LYSSC  E=1e-79 s/c=0.45 id=24% cov=72%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNATGLAIVEKtPEKRQEWFEKFYDQLVSLKFIPAGRVIYGAGSeTDVTFFNCYVMPfVADSREGISDHRKQVMEIMSRGGGVGTNGSTLRPRNTLARGVNGKSSGSVSWLDDIAKLTHLVEQGGSRRGAQMIMLADWHPDIVEFIIskmqnprilryLIENTTDEtiirlakeklnfkplsmqeeamyqgivnyksieglggfdtaiireaENKLRDggtytvhnpefltgANISVTLTKEFMEAVENDDDFEL----RFPAVEEYSKEEMSAYNTEWhnvgdvREWEKMGyKIRtYRTIKAKELWNLINVCATYSAEPGIFFIDNANDMTNAKAYGQSVVATNPCGE--QPLAPYS----------VCNLAAVNLAQFankdnqtVDYEALRETVRVGVRMQDNVIDATPYFLEENRVQALGERRVGLGVMGLADLLIYCEKEYGSEAGNALVDEIFKTIAETAYEASTELAKERGSFPFLVGA-TDEETARLRKAFTETGFMEKMPAH-----IKEQILATGIRNSHLLTVAPTGSTGTMVGVATGLEPYFSFTYYRSGRLGKFIEVKAEIvkeyldrhpeaneQELPEWFVTAMELKP-EAHADVQCIIQKWIDSSISKTVN------APKGYTVQQVEKVYERLYKGGAKggTVYVDGSRDSqvltLKAEENDMDQLSFEEE--------
>UniRef50_Q11ZE1(21-608:858) Ribonucleotide reductase large subunit n=2 Tax=Burkholderiales RepID=Q11ZE1_POLSJ  E=2e-79 s/c=0.51 id=24% cov=67%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------EIFARVAKGIAQAEQPELREKYERVFFDNMMRGAIG-AGRIMSAAGTgIKATLANCFVQPVGDAIQgvdtegypGIYEALREAAETMRRGGGVGYDFSRIRPRGSVVKGTASSASGPCSYIDVFDASCKTVESAGARRGAQMGVMKISHPDILEFITAKREVG----RWNNFNVSVGIVDGFMAAVEANEMW--------PLVHKAEPSVEQQRAGAYLR-ESDGLWVYREVPAAEIWDTVMKSCYDFAEPGIVFLDLMNLDNNL-SYVETIEATNPCAE--QPLPPY----------GCCDLGPIILPKFvsrafteraaFDDEGFKAAVKIQTRFLDNVLSVTHWPLEQQRKEAEAKRRIGAGFTGLGDMLAMLGIRYNSIEGVEFSRHVALMMRDAAYEASIDLAIEKGPFPLFD----------ADKYLKKGTFASRLP-----KSLKDRIRRHGIRNSHLLSIAPTGTVSLAFadNASNGIEPPFALAYTRKKRVGdghvnynvvdhafrVFLETVcaqelraPLLEAVS-RYQPAFEVAGKTYQVKdcippsivtaqemsaaehlaVMAAVQPLIDTAISKTVNV------PEDYPYDDFKNLYMQAWKANLK----------------------------------
>UniRef50_A7HK53(2-634:841) Ribonucleoside-diphosphate reductase n=11 Tax=Thermotogaceae RepID=A7HK53_FERNB  E=2e-78 s/c=0.47 id=23% cov=72%
---------------------------------------------------------------------------------------------------------------------------------TLTSVIEHWKDVELSKNAYKILSERYFLKTP-SGEFLEKSWDDICRrvarvIATAELVNNPelkeksPFEQLDEVKfwesTFFDFLKSRIFIPNSPTLFNAgmgvrhellwksiddmtledyweiynsRNHLHMLSACFVVPVEDSIEGIFEAVKEYALITKAGGGIGSNFSRLRPKGSFVAGTHGQASGPVSFMHVFNSAVGVVEQGYRRRGALMGILNIDHPDIEEFITAKEgNDGEKVLKFFNISVGIT-----MDR---------------QELLKLYMEDGE-IELKHPKCNGS-----KRVKVRELINKIAKNAWKTGDPGLAFLSEMNKYYAMYPEM-TIESTNPCGEIGLAPYEA------------CNLGSIDVAKFYMngefyWEAFAQATRLAVRFLDDVIDVNVFPLEKIRKAVTDSRRIGLGIMGFADLLYMMDIPYNSHEGRQFAADMTAYMAIHGHDESNKLAQLKGSFPLFEKSRYYRedEFAPFAMGMSKYDNELKEVFKES---------KKGKRNVAVLTIAPTGSISNIADTSSGLEPNFLLAYVRymnkhdgtkealfyvnkvlesklnkeileRVKDklverGSLQDIPEIPEEIKRVFVTAMDISPMDHLL-MQDAFQRYVDNNISKTINM------PNSATEEDVLNIYLEAMKLNIRglTIY-------------------------------
>UniRef50_C4NT50(16-572:776) Putative ribonucleoside-diphosphate redutase n=2 Tax=unclassified N4-like viruses RepID=C4NT50_9CAUD  E=5e-77 s/c=0.52 id=25% cov=64%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HFHNNHAEREALEA--RFYNALYDFKFLPAGRINSGAGTGRNvTLFNCYVMgTIPDSLDGIFDMLKEAALTMQQGGGIGYDFSTLRPKGALVKGVESFSSGPLTFMDVWDSMCKTIMSAGSRRGAMMATMRCDHPDIMEFVTAKQ----DPLRLRNFNVSVLCTDEFMEAVAADSDWDLM------------------FDGK----------VYQTIKAKELWETILWNTYNYAEPGVIFIDRINKENNL-WFLETIAATNPCGE--QPLPPYGA----------CLLGSVNLAKHVvfpfvkgqaeiDMKALEESVRTGVRILDSVVETSLFPLEAQRDEARFKRRQGLGVTGLADALFMTGHRYGNQQAVNFTDTIMMNIAIWAYEESIQMAKEMGPAPC---------LVPLEAREKFIQSGFMQRMP---EYIKDDILEWGIRNSHLLSVAPTGTISMYAGNvSSGGEPIFAPKYQRKvtNDDGTKRtETVYDYAVLKFEEHfgendnpeaiWWWENYMATAQdltpsdhIVMQAVLQKWVDSSISKTVNL------PEDISFDDFKAVYDHAYTTGCKgcTTY-------------------------------
>UniRef50_B2KX75(219-811:850) Ribonucleoside-diphosphate reductase n=2 Tax=Spodoptera frugiperda MNPV RepID=B2KX75_NPVSF  E=7e-71 s/c=0.46 id=21% cov=65%
--------------------------------------------------------------------------------------------------------------------------------EELNKVLRHDRDYTYD-----------LRLYENKNNLLERVQHMFMRVALTMYGD-----DIQKVIESYHMMSLRMYAHSDLAFACAGTNSTQLANdykLYVDNCSDNIFLSYKIIQECATIMNCGGAVDLYMQNV----------------SVKMLPVFNNMVRHILHKNKIVKLPTIHIELWHHEVKNFIETIRNNSD---KVNFLQFTVDIPDIFMNRVKNNGYWTLLDPESCTSLSSKY---GDKFEQAYVKFEKE-HINAKIVKAKDLLKLIIDTMRINGNLSVMFKDTFN--NNFS--------------IEDEQVKYNIVFSASVAVDKC----VNLeTKQFDYNLLRRITKNVVRDLDAMININMYPLDKFE--NKKH-NIAVGMQGFAETLLLLGYTFDMVEAKALNKLIAETIYYGAIEASNELAEaskelnESGKKKSHRNEKITQQIYNV--------YTDNETLMWDWQSLHEKVERYGVKH--VTFVSNTYKTAfEILGTKTTSGPFNSFLYQIEkinyieevlvralahenlntptvinsilaTKNGSVQNNDLIPDHIKKVFKLNTETDCKQ--LDYMIENSPYIDQTQELILH---------------------------------------------------------------
>UniRef50_O31875(766-1084:1084) Bsu nrdEB intein n=33 Tax=root RepID=NRDEB_BACSU   E=7e-57 s/c=0.71 id=24% cov=40%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CSEVLQSSQVSvytdYDKEDEIGLDISCNLGSMNIVNVMSNQSIASTVRIAIDSLTTVTRKTNIVnAPAVARANTLMRSIGLGQMNLHGFLAQNNIAYESEEAKDFANTYFMMVNFYSLQRSMEIARETGeTYYKFDGSTYKSGEYfekyvtndysPQYEKVKKLFGDQHIPNIQDWMKLKEDVMKYGLYHSYRQAIAPTGSISYVQSSTAGVMPIMERIEERTYGNSKTYYPMPGLSaQNWFFYKEAYDMDMFK-VVDLIATIQQHVDQGISFTLFLKDT------MTTRDLNRIDLYAHHRGIKTLYYARTKD------------TTQEGCLSCVV--
>UniRef50_Q120H3(19-608:784) Ribonucleotide reductase large subunit n=1 Tax=Polaromonas sp. JS666 RepID=Q120H3_POLSJ  E=1e-68 s/c=0.45 id=23% cov=61%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFVQPVGDSMSgsnqdgqpGIMDALRESAETMRRGGGVGYDFSSIRPVGARVKGTDSKASGPVSYMRVFDRMCQTVESAGARRGAQMGVMRVDHPDIEMFIDAKKtpdfsQMGLDKKDADglldlvrknqgfgwslrsafatlsNFNISVAVTDEFMNAVVNDSDFDLVhDAEPVEACPTKVCTDGK------------ARFVYRTVKAIEIWTKIMRNTYYGAEPGVLFIDRINQDNNL-RYCEVIKATNPCGEQTLPP------------YGCCCLGSPNLTRFvsnpftlmasFDFDGLSKVVAKAVEMLDKVLDKTHWPLPQQASEAANKRRIGLGHFGLADAMAMLGIRYDSQQGADFAAHVSEVLRDSAYMASVNLAKTLGAFPFFDAEKY----LEEGTFASRLP-----------EKIKDAIRMYGIRNSHLLSIAPTGTISMAFGDNASsgIEPIFSLRQQRNKMMADGSRQIFELEDYayrqfklskgEDAKSDVFVTAMQMTVadhLRVLGAVAPYIDSAISKTVNV------PADYPFEDFQQVYMDAWRMGLKgiTTY-------------------------------
>UniRef50_B6YRR4(11-630:867) Ribonucleoside-diphosphate reductase n=21 Tax=root RepID=B6YRR4_AZOPC  E=4e-66 s/c=0.41 id=25% cov=69%
--------------------------------------------------------------------------------------------------------------------------------------------------AAKVFVDKYALKSN-KGEYFEsTPNEMHQRIAREIVRIEQKyPNPILTEKNILEVISDFNYLIPqGGNMFGIGNSYqlTSLSNCFVIGNrTDSYGGIMRTDEEQIQLMKRRGGVGHDLSHIRPRGSPVNNSAITSTGMVPFMERYSNSTREVAQEGRR-GALMLSMSVEHPEIESFIDAK----IEEGKVTGANISVKLTDEFMRAVESNRS----------------------FIQRFPIDSENPQIIKE-IDAKDLWNKIIHNAWQSAEPGVLFWDTILRESipdcYIDSGFGTV-STNPCGEI--PLCPYDS----------CRLLAINLysyvkqpfkkEAEFDFDLFEEHVALAQRMMDNIVDlevekidailmkiISDYESDEIKHTEQllwekiRHktligRRIGIGITAEGDMLAALGFRYGTEEATNFAERIQKVLALSVYRASVEVAKERGAFEIFN------------IELEKNNPFIHRLKEVD-SQLIEDMQQFGRRNIACLTIAPTGTTSLMSQTTSGIEPVFLPVYKRRRKVNPSDEITKidfvDEMGDSWVEYTVFHHKFVKWMevqgypttrkyaqreidalvakspyykstsndvdwlqkVKMQGRIQRWVDHSISVTINL------PNETKEELVNYLYIEAWKSGCKgcTVY-------------------------------
>UniRef50_Q5DN91(53-590:602) Ribonucleotide reductase n=1 Tax=Phage phiJL001 RepID=Q5DN91_9CAUD   E=7e-66 s/c=0.47 id=25% cov=60%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CYVSgTIEDSfIDGhgsIMERAKQAAATMRMGGGIGYDFSTLRPNGALIKKLQSRSSGPLSFMQIYDSVCKCVASSGHRRGAQMGVLRVDHPDIEEFIRAKHN----EDNLTGFNTSIAITDRFMECVISGEPFPL-----------TFGGE-----------------TYRSINAENLWEMIMRSTWDWAEPGTLFIDQINRMNNL-KYCETIAATNPCGE--QPLPPYGA----------CLLGSFNLVKyvkpftgrvfvvgadsrwTFDWDLFATDVYAVVRAMDNVVDRAIYPLFEQEKEAKSKRRMGLGVTALANAAEALGMPYGSIEFLKFEGQVLETLACNSYQASVELAQEKGAFPLYDEryldSEYVRQVLP--------------------EELQEDIGRYGIRNSHLTSIAPTGTISLTAdNVSSGIEPVFSYGYDRTVhmPDGVRTERVDDYGvRVFGVEGKTSDQVTAEEHVDVLTVAQGFVDSAVSKTCNVAP------DMPWEDFKQIYFRAWEGGAKgcTTF--NSggkRFGVLRSDDDDQSNIEGEAC-------
>UniRef50_A2BL44(67-900:991) Ribonucleoside-diphosphate reductase n=2 Tax=Desulfurococcales RepID=A2BL44_HYPBU  E=9e-66 s/c=0.30 id=24% cov=74%
-------------------------------------------------------------------------------------------------------------------------------------------DKGFTYNAIRVLLARYMVRNEY-GVPMETPSMVMARVAWGF------STRVDPV-KLYRLLIARKFMFNSPTLFNMYVdgAYGTLSACYVTPVYDDMKAIMDAATVQAMTFKWGGGQGFSFSELRPRWDIVRSTGGQASGPLSFMQIYDMVTETVKQGGKRRGANMGIMHAWHPDIYNphfnpwhalrnmlppqlkalidttkrliehleregyeidpvykeivmrlseegwetvedagFIQAKEPPLQDANLT-NFNISVAANDAFMQAILRGEDWWMVNPRYsdsgdgvyrlhysvsratglgrLGELLERYPWLLENpylniFEdvleeaktkalealkeqARYTGWETSPEQKNPyawKYPARKLWEKIVENAWASGDPGLFFPDNHNKWNPT-PWLGAVYATNPCGE--QPLYPFES----------CNLGSMSIDKYisdgkFDLAQFMSDIQLAVDSMDAVIDFNKHPDPRQTVANKFTRKIGLGIMGLADALAKLGYPYDSEEAVAFTLIVMAALEVYSWKRSWELGAKLGHAPAFEcrrydwksmrcvekaepeelvelhtpallkASRISRvedGWLkvcyhaveiPEDMLERLVGEAKSRIEPngtvklVRWEAVekvlrevfgvtREDyeralrsspvivvnspklllalavynpeaawkvLKAYGRslgarapRNTVMTTVAPTGTISIIAGTSSGIEPYFALVYRRVVAIGEFLEVVKPFREKlleaarrynvpLDAVKVVYEtIGRHKGSLRWAlgevrekliqmgimngflaeveklarlftmsmdfdlwyhlahqIAAQLYVDQAISKTINL------RKDATKDEVYTAYLVAWLGGLKgvTVY-------------------------------
>UniRef50_C9DFZ9(25-595:711) Ribonucleotide-diphosphate reductase subunit alpha n=1 Tax=Deftia phage phiW-14 RepID=C9DFZ9_9CAUD  E=1e-65 s/c=0.44 id=22% cov=63%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAHAQRLYDYASKDDFIWASPAFSNATLPGEKIRampiSCFLPDVPDSVPGLLYQKAELSLLS-------VLGGGVGQNFGGIRSVSDKAPGPIPFIAENDSAILAWKQGKIRRGALSANLGVTHPDTMEFMRIRVPTGDIERKSLNIHHGFNVTDEYMQAVVDGiETLPLIDP------TGKQVGSM---------------------NPREHFREMVTVRSRTGEPFMYFIDRAQEYlSLPQKLIGMAcKATNICTEITLAAT--------KDRTPVCCLCSINAERYEDFKpYYQEMVSDLIEMLDNIIeffvqnvekvaegyadqldrDLIRLLVQKVKKSAECERSVGLGVMGLAYMLQRADMVFAGEDSREYELEFFRQLKDFSHAASCRLGIERGVPPDIQ------------AYLEKCKELGIEPDPY-W------VNR---RNLHLLAIAPNANSSVILNTSASIEFMYSNVYSREMRTGTFEvrnrylekllesqgrnteevwnqikadsGSVKGLDFLTEHQKRVYAVPEEMNMMDVvvrAGERQVYICQAQSLNLFFPPGSDINF------VMAVHILAWKVGVKSLYYYKTES-------------------------
>UniRef50_C8WXT6(93-298:1065) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WXT6_ALIAD  E=3e-13 s/c=0.39 id=19% cov=26%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------LLETsPRQMWRRVARGAAAVTRQPE--VWEEAFYELQKGWRYVPGGRINASLGTGM-QVTSynCFVIpNVGPDLRDYAESFGQTLEIQARSGGVGMNLSRIPPQGTLI-----------PV-----STAS-------RKAELMLVLDAWHPDLVDFLETEYPHSTKLVRADAA---------FWRAVEEDDEWVFRFPDtSVEGYDEKWAGDLDAWLRQGLPVEEHGRIR-----ARELMEKIL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9J500(3-531:580) Putative uncharacterized protein gp07 n=2 Tax=unclassified Siphoviridae RepID=A9J500_9CAUD  E=1e-59 s/c=0.44 id=22% cov=58%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIMVRAAEAAATMRMGGGIGYDFSTLRPRGDLIRKLQSHSSGPISFMHIFDAICKCVASSGHRRGAQMGVMRVDHPDIEEFIHAKQPG-------KDVQP-LW--DLVAELPEGAQKQQLiMSLQQTLKLTGFNVSV--AITDKFMECVASGEPfpltfegrTYREVDARALWDAIMRGTWDWAEPGVLFIDAINRMNNLWYCE-TIAATNPCGE--QPLPPYGA----------CLLGSFNLVKyiykdgagcfAFDWDQYREDIPQVVRAMDNVVDRAIYPLPQQKQEAKDKRRMGLGITGLANAAEALGHEYGSPAFLAFEAEVLDTLRDESYLASAHIAKVKGSFPKFDKDKYLQGQFIKTLR----------------EDVRDAIAKYGIRNSHLTSIAPTGTISLCAdNVSSGIEPVFAYSFDRTVIefSGPRVETVEDYgaRVFGVRGKTCSRVTVQEHVAALTVAAQR-VDSAVS------KTCNVPSDISWEDFKNVYVSAWEGGAK----------------------------------
>UniRef50_B2UIU6(20-596:605) Ribonucleoside-diphosphate reductase n=3 Tax=Ralstonia RepID=B2UIU6_RALPJ  E=9e-58 s/c=0.40 id=20% cov=71%
------------------------------------------------------------------------------------------------------------------------------------------------------LADRYLAPGET------TCNDVFKRVAHALAAAEQPDQRAHFTRLFYANLLQGAIG-AGRIMANAGSaNHGTMVNCFVHPIGASEQSVADasdverALHAAQRTLQMGGGVGYDFSVIAPADAEQATSNSGTGSVCAVLDSFDRVCATQALVNTRGGAQMAVLRCDHPDLATFITAKRG----RRRWATFNLSVAVTDAFMRAVADDGLWCL-QHRAVPNAQRLATG---------AHALSNGKWCYAVVPARQLWNMIAEAAHHSAEPGLLFIDTINAANDLAE-IETIAATNPCGE--QPLPPWGS----------CVLGPIDVSRWvqwpfgmggqplFDFVGLSRAVRVQVRMLDNAIEITRWPLPEHMHEAQAKRRIGVGVTGLADALTMMCLPYDAPAARCFAAQIGRCLRDSAYAASAALACERGPYPLF--SP-ERSLAPGHFSAALPKAVC------------EAVAKHGLRNSHLLSLAPTGSVSLAFGdnCSSGIEPAFDWVYQRRVR--IQHRAPQLYRTENRAYRLFRALYGQRAAlpgyfvtarqidgldhLRMVATLQPFVDASIS------KTVLLPCSASCAQVAALLFHAWQLRLKGITIFRPDTGPDDVLSELPP--------------
>UniRef50_C9M6M1(154-704:881) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Jonquetella anthropi E3_33 E1 RepID=C9M6M1_9BACT  E=2e-57 s/c=0.41 id=21% cov=62%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTANQQLFACFVVSVPDSIEGIFDAVKDAAIISKYGGGVGANFGHLRESGAPIKgGTGGKASGPVSFMETWNTMGSVVVQGGRRRAALMGMLPDNHPDIERFMDAKT----EDGRLPYFNISVCVSDRLVNAAREGGDFPLVS-----------RVDGK---------------TAATVPAAQLWDKLCSNAWRRGDPGVFFIDRAGADNLLREDpEFVIESTNPCGEQPLPNYTS------------CNLGSINLSAFvapdgsgqlaFDEARFVDQVYRSMVYLDLVIDSCSYPLERIGRRTRQIRPVGLGLMGLSDAAIASGLVYGSPEFSGFCDRLASVMAVCALLATVDSVDHLGKEP-FAASSAVVKLFAPLRDELGGDLFMSQTMETldeegflrvvgrmkelglpytlcntlqaapgvlkrleggSPEELRRllgAVLGGRMRNSRRLSIAPTGSISMLLDASAGIEPnfawswnrkvmksdgngyETRQYFHRLVTDEGKRQLSAGGKLEDPRFVTAYDLSP-EGHVEVTGIFARYVDSGISKTVNL------PSSATVDDVKAVYERCYDLGCKgiTIY----RDGSRSEQ-------------------
>UniRef50_D0LZM4(137-705:963) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Bacteria RepID=D0LZM4_HALO1  E=3e-57 s/c=0.40 id=20% cov=64%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DELVHLLVNQKMAFNSPVWFNVGVeTEPQCSACFINSVDDSMSSILTLARTEGMLFKYGSGTGSNLSSLRSSAENLHGG-GTASGPVSFMRGFDAFAGAIKSGGKtRRAAKMVILDAEHPDIVDFVECK---AKEEQKAwalidagydggfnepggaydsvnyQNANHSVRVSDSFMQAVVDDSSWTTHAVLDGRDIH--------------------------TMPARELMRKIADAAHLCGDPGMQFDSTINDWNPC---IGTarINASNPCSE-------YMFLDDSA-----CNLASLNLRRFqsedgnFDVEAYKHAIEITTLAMEIIVDNASYPTPKIGENSHRFRPLGLGYANLGALLMSRGLPYDSEPGRAYAAALTAILCGQAYRTSARIAADaTGPFAGYDEnrepflrvmNKHRKAVADIDAALVPYDLM--EAARGAWNDVVELGEKHGFRNAQTTVLAPTGTIAFLMDCdTTGVEPDIALVKYKRLVGGgmlkMVNQTVPEaLRRLGYSEQQLEgiinHIDTQESIegtsvlkeehlpvfdcafrspsgtrsihymghIRMMSAVQPFLSGAISKTVNL------PSDCTVGDIEDAYLQAWKLGLKAI--------------------------------
>UniRef50_A4L245(22-682:683) Ribonucleotide reductase large subunit n=1 Tax=Gryllus bimaculatus nudivirus RepID=A4L245_9VIRU  E=3e-57 s/c=0.34 id=20% cov=74%
--------------------------------------------------------------------------------------------------------------------------------------------YIFTGAAIQLLQERYLNKG-------ENIQEGFARIAsyFCDNSNVPLWRNIykclsatnilvsSVIARYQDTYSSSYATVAGVTRDEDTTTKGK--ACLLAVMPEKYNEDALRLMwKLFDYLAKGIGIGLCIDNVPKYGSdgyeYIKGG----------IHEFLDLLSHVNgvRITKRESNFAVYISIYRDTLYDVLNIRQRN---KNKLLNVFPAVKIPNMFMKKVRNNEAWYLFDVTES-QLLDKTKNE-KEFEELYETFVSEQKYTNMY-ESRKIFKDIIKNILMTGSPYIIFIDNVNKFNNI-KHLGKIKTLNLCSEITNY--------CNEDVISTCLLLSVNVANFKHQWDLVSSLENILskefnvnfKDDDFVIELDetsklcwsyckimgFLATVCLNYflGSSKRREIGVSPLGVYDAIIISKT----DQPLFFCKLISESLYKGCVLASVAWSKKFGiRCKNFENSCFSRGEFQFDLRNLTYKNIS------DWSSLKRDVLLYGMANSLLTCQAPTATTSLLADVTPSVtEPhdccdfiCREHSFRSLSLSYVMKNffIKNNVEMINFSKKLF----QLKLSKNLYKVSLPYIDQSQSVILN--------GNFSSLELMEYLIYAYNNDFKTaLYYINLKSTGTSMLYD-DTKKENEICDSCS---
>UniRef50_O69981(132-718:967) Vitamin B12-dependent ribonucleotide reductase n=38 Tax=Actinomycetales RepID=NRDJ_STRCO  E=3e-57 s/c=0.39 id=24% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSFNSPVWFNVGTPQPqQVSACFILSVDDSMESILDWYKEEGMIFKGGSGAGLNLSRIRSSKELLSSGGNAS-GPVSFMRGADASAGTIKSGGaTRRAAKMVILDVDHPDIEDFIQTKV---KEEEKIRalrdagfDMDLGgdditsvqyqnannsVRVNDTFMKAVQDGGKFGLTS-----------RMTGEVIEE---------------VDAKALFRKMAEAAWACADPGIQYDDTINAWHTC-PESGRINGSNPCSE------------YMHLDNTSCNLASLNLMKFlkddgkgnqsFDAERFSKVVELVITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYDSDGGRALAGAITSLMTGTSYRRSAELAAIVGPYDGY-----ARNAKPHLRVMKQHSDENAKAVRMDdldtpiwaaateaWQDVLRLGEKNGFRNSQASVIAPTGTIGLAMSCdTTGLEPDLALVKFKKLVGGGSMQIVNgtvpqalrrlgyqeeqieaivahiaengnviDAPGLKPEHYEVFDCAMGERSIsamghvRMMAAIQPWISGALSKTVNLPESA------TVEDVEEVYFEAWKMGVKAL--------------------------------
>UniRef50_C9MSK4(68-703:902) Ribonucleoside-diphosphate reductase n=8 Tax=Prevotella RepID=C9MSK4_9BACT  E=2e-56 s/c=0.35 id=25% cov=69%
--------------------------------------------------------------------------------------------------------------------------------------------------------NKYAMKDSLGNIYEKSPEQMHRRIAKEIARIEHKYKNPLTEEEIFNLLDHFRYIIPagSPmTGIGNDHQVASLSNCFVIGLDgdaDSYGAILRIDEEQVQLMKRRGGVGHDLSHIRPKGSPVHNSALTSTGLVPFMERYSNSTREVAQDGRR-GALMLSVSIKHPDSEAFIDAKM----EEGKVTGANVSVKITDEFMRAAIDDK------PYE-----QQFPIDSTE-----------PKCTKK-VSAKALWEKIVHNAWKSAEPGVLFWDTIIRESIPDCYADLGFrtvSTNPCGEI--PLCPYDS----------CRLLSLNLysyvldpftdHACFDFDLFSKHAQLAQRIMDDIVDLemekidlimakvkSDPQVDEVKeaeyhlwekikdKSGKGRRT-GVGITAEGDMIAAMGLRYGTQEATDFSVSVHRALALNAYRSSVRMAEERGAFAIYDAKR--EEHNPFILRLKEADA-----------QLYEEMIRYGRRNIACLTIAPTGTTSLMTQTTSGIEPVFMPVYKRRRKvnPNDTDVHVDFVDEVGDSFEEYivyhrkfltWmevngidtqkkysqeEIDtlvkrspyykatanDVDWLmkVRMQGTIQKWVDHSISVTVNL------PNSVDEALVNKLYVEAWRSGCKgcTIYRDGSRSG------------------------
>UniRef50_Q3AEA3(627-904:1101) Ribonucleoside-diphosphate reductase n=2 Tax=Bacteria RepID=Q3AEA3_CARHZ  E=7e-52 s/c=0.75 id=30% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLGSINLANMVkdgeiDWEHLEKTVKLAVRFLDNVIDVNHYPLPEIEKMTKKTRKIGLGVMGFADMLIKLNIPYDSEEALNLADKVMEFINKKSKEASAELARVRGTFPAWKKSVWAK------------------------KGLK-------LRNATTTTIAPTGSISIIAGVSSGIEPVFALAFKRHILDrkdivevhrlfeqharengyyseklmnevaktGRITGIAGVPEEAKRLFVTALDI-APEWHVKMQAVFQKHTDNAVSKTINM------PNSATVEDVKESYLLAYKLGCKglTVY----RDGSREEQ-------------------
>UniRef50_D2RTR9(143-654:1042) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Halobacteriaceae RepID=D2RTR9_9EURY  E=2e-54 s/c=0.42 id=21% cov=56%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVAEEFQGMMENLDFMPNSPTLMNAGDELQQLSACFVDSPDDDIDDIHQTAKEAAQVFQSGGGMGYAFWQLRPYGDAVGSTGGIASGPITFMRTYDQMCETIAQGGARRGAQMGVMRVSHPDVIQFIHaknkdvslaetLRLNDPDDfthnsfqealdeareliddegkvpkhlrnavEGHLSNFNISVGITDDFMEALQNGEEFTFTNPRtgephiataETKELYDMFGLGD------YVEVGEELS-----IPAEELWDDIVEGAHENGEPGVIYLERVNKQHSFdveKHPDHRILATNPCGE-----QPLEEYEA-------CNLGHINLStladleapdwrvwydehgeeydsledavdafleEAIDFEEFDRRIEMGTRFLENVVTMSDFPVEKIEQKVREMRKIGLGIMGLAQLYIQLGMEYGSETSNEVARQLMRHINHGSKWASHELAEERGSFDEWDNSKYAN-PTEYREWFEKQTGLDAD----EWED------GFSIRNHNTTTIAPTGTTSMVGNTTGGCEPIYNVAYYKNVSD----------------------------------------------------------------------------------------------------------------
>UniRef50_D1JF25(616-882:919) Ribonucleoside-diphosphate reductase n=1 Tax=uncultured archaeon RepID=D1JF25_9ARCH  E=7e-39 s/c=0.62 id=23% cov=30%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLGSINVSKFVengeiDWERLKEAVWSSVRFLDDVIDENRYPLSKIEKMTKANRKIGLGIMGLAELLIKLKIAYDSKDAVLMAEKLMQFITNEARQCSTELGLEKGSFPNFELSVWST----YDA----------------------------MRNATVTTIAPTGTIGIIGNCSSGIEPLFAVAFVRNVMGGMleinklfeeiakekgfyskeliaeiakrgsIQDIAGIPEDIKRVFVTALDISP-EWHVRMQAAFQRYTDNAVSKTVNL------PSDATRGDVKRVFLLAYKLKCKgvTVY-------------------------------
>UniRef50_B9L1R5(196-661:1122) B12-dependent ribonucleoside diphosphate reductase n=2 Tax=Bacteria RepID=B9L1R5_THERP  E=7e-51 s/c=0.44 id=25% cov=53%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFIQSVEDDLvnpGGIFDLVLREARVFKYGAGSGTNFSKIRAEGEPLSGG-GTSSGLMSFLKVFDRAAGAIKSGGtTRRAAKMVVVDIDHPDIEKFIRWK---AEEEKKVaalvaagysadfngeayatvsgQNSNNSVRVPDEFIRAVLEDRDWHL-----------RWRTDG--------------RIAK-TVRARELWQMIAEAAWQCADPGIQYDTTINDWHTC-PASGRINASNPCSEYMF-----------LDDTA-CNLASLNLLKFYDAKSGRfdiAAFRHAVRLWTIVLEITvlmaQYPSREIAWNSYRFRTLGLGYANLGSLLMTMGLPYDSDRARAVAAAITAIMTGEAYATSAEMAAILGPFPAFPENREHMLRVirnhrraAYDAHPEEYEGLHIAPQGLDathcppelvaaareaWDRALELGERFGYRNAQATLLAPTGTIGLLMDCdTTGIEPDFALVKFKKLAGGgyfkiVNRSVAPALERLGYTPEQIQDI-----------------------------------------------------------------------------------------
>UniRef50_A4WLF4(823-1182:1240) Ribonucleoside-diphosphate reductase n=2 Tax=Thermoproteaceae RepID=A4WLF4_PYRAR  E=3e-43 s/c=0.50 id=27% cov=31%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VCNLTHINLVKFVkdncgggsfeeklgciDWDGLAQAARVGTRFLDDAIDRSKTGIEVIDEMNAATRKNGLGIMGFAELLIKLGVPYASWEAVELINRIMGWIYVNALDESAELAREKGPFKFFHKSIYARGEIPVlkfqdhvwsrwerikRVYPRELqeagDKLRDITMRTRqWlgpylDKLSEKV-RGGVRNSVVLSIAPTGRTSILAGTTSGVEPVFALAFLRNVTVGtlveyyepgiellksrglWTPQVrkvveetgmlrdAPVPEDVKHLLATAMEI-GWLWHVLMQASAQQWVDQGISKTINM--------------------------------------------------------------
>UniRef50_Q5JJ43(6-301:1746) Ribonucleoside-diphosphate reductase n=3 Tax=Thermococcaceae RepID=Q5JJ43_PYRKO  E=6e-14 s/c=0.28 id=19% cov=29%
------VMKRDGRIVPFDKERIRWAIQRAMLEVGVRDEKLLNRVVRRVVR---RVNELYDGQI-----------PNIENIQDIVELELMRAGLFDVAKAYILYRKKK-------------AEIREEKKKILNKDKLDEIDKRFSLNALRVLASRYLIKNE-KGEIIESPRELFERVAiLAVIPDILYDERVfdknggheqdvsaieryrenldeydgkfsigrfrlnkwhferllnlyrelaekgqmklpidevlkmlengafdnyeDEIEEYFRLMTGQYFMPNTPALINSGRPLGMLSACFVVPIEDDMESIMKAAHDVAMIQKAGGG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8G0R6(661-941:1153) Ribonucleoside-diphosphate reductase n=5 Tax=Bacteria RepID=B8G0R6_DESHD  E=3e-42 s/c=0.63 id=30% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLGSINLklmvtekngKVVVDWERLGQITRLATRFLDNVIEANTYPLPSIEEMVKGNRKIGLGVMGFADMLILLQTSYASEDAVEYAEKVMNFIQTEARLESQRLAEERGTFPNYQGSIYD-GVRP-------------------------------LRNATLTTIAPTGTISMICGASSGVEPLFAVAYTKTVMDGTpLIEVNPIFQSLAEDYGFnspelmrkiaekgtvlgFPEVPNwvqevfvtaqeiePEWHIRIQAAFQKYTDNAVSKTINFA------NEATHEDIAKAYELAHELNCKglTVY----RDGSREEQ-------------------
>UniRef50_Q9UYA0(6-301:2122) Ribonucleoside-diphosphate reductase n=2 Tax=Pyrococcus RepID=Q9UYA0_PYRAB  E=2e-14 s/c=0.28 id=19% cov=29%
------VMKRDGRIVPFDESRIRWAVQRAMW--------------EVGVRDERKLDEVVKNIVKRINELYDGKIPHIENIQDIVELELMRAGLFEVAKAYILYRKKK-------------AEIREEKKRILNKKELDEIDKRFSINALRVLASRYLKRDE-NGNIIESPRELFERVSiLAVIPDLLYDERVfdkdgnykqdlkrveyylenfekfdgkysigkyklnkyhfermvnlyrelaekgkmkvsideflsmlergefdkyeKEIEEYFKLMTNQVFMPNTPALINSGRPLGMLSACFVVPIEDDMESIMKAAHDVAMIQKMGGG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1F6S8(181-752:1083) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F6S8_ACIC5  E=3e-48 s/c=0.34 id=22% cov=60%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQCSACFINAVDDSLDSILTLAKTEGMLFKWGSGTGTNLSPIRGSMEQLSGG-GTASGPLSFMRGFDAFAGVIKSGGKtRRAAKMVILNVDHPDIVDFIECKM---KEEAKAwalmregydgssgpdseayssiffQNANNSVRVNDEFMRAVEKDGEFT-------------------------TRTVKDGAAVKTY-KAREIMHKIAEATWQCGDPGMQYDSTINRWH-TSKNSGRINASNPCSEYMFL------------DNSACNLASFNLLKFmtpagtFDIRAYRHAIDVLITAMEILVDNSGYPTENIARNSHDYRPLGLGYANLGALLMALGLPYDSDAGRDFAATLTAIMCGEAYLQSSRIAEkcpplasatpltasvERngGACPGFYvnrepfldvirmhraevnkigKSKTSSEPFKVP----ELDALITASKEC-WDQALAHGEKYGYRNSQVTVLAPTGTIGFMMDCdTTGIEPDLALVKYKKLVGGGMIKIVNNTVPA-ALFKLGYKNEDVDAIvsyidatgtiegapgikpehlavfdcsfkpakgtrsihylghIKMMAATQPFLSGAISKTVNM------PHDSNIDDIAEAYLESWRQGLK----------------------------------
>UniRef50_Q6QXF6(17-614:615) ORF37 n=3 Tax=Baculoviridae RepID=Q6QXF6_GVAS   E=2e-46 s/c=0.32 id=20% cov=69%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------VETPEEFCQRISRGMVKLDDEEKKIAHATA---LLSSVSIIPSSALcqHLNLQRNDTTPSACHLTVFSHSYEafSKLNELDRIAKMAIMGTGVGVGGDYLRYKGSNVAGELKNS--FVEICQYLNAATTLN--VSARKSRVAVFLSLHHICSMICLTLRQQNA---RVTSNIFYGVMIPNFFMEmqRKDKNAMWYFFDGNTTLEGLSLNDCYGEEYESLYWRMVEKKLYVKK-MYATQVLGELISCLTENGFPYVVWRDHVNMFNNHRD-LGTIQTLNLCTEICQ--------HAGSDSSSMCTLMTVNIAAYcedYPLCKMYEeiVEELAEYGLHQCC-PQFDETNEARllmhcftasytSTFLLNRLLGdktsrreLGVtpTGLFDAVYILcgRDAAYNDAMIHYSALVAEYMYIGCVLSSIVYNRKFNViCVNFSKSEFAKGLFQFDLRN------VTPSLSLLWNRIRPFMKK-GMANSMLTAQAPTATTSLLTNVTESVQFPMSGAVQTTKNSGTGRFANIPF----FLYKSNEtDIGFNRPVtiakqVQVFAKMAPYVDQSQSV--------IINCSSTYEDVFRILRYTYDNKLKTaLYY------------------------------
>UniRef50_Q8UEM4(193-772:1272) Vitamin B12-dependent ribonucleotide reductase n=163 Tax=root RepID=NRDJ_AGRT5  E=3e-43 s/c=0.31 id=23% cov=54%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPQPHACFIQSVEDDLvneGGIMDLWVREARLFKYGSGTGSNFSYLRGEGEKLSGG-GKSSGLMSFLKIGDRAAGAIKSGGtTRRAAKMVVVDADHPDIEAYIDWKVN---EEQKVAALVTGSKIVakhlKAIMKACVNceadNGD--CFDPAKNPALkreiraakkdmvPENYVKRVIQFaeqgykdiqfktydtdwdSEAYltvsgqnsnnsvslkddflRAVENDGNWnltarkdgkVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWH-TSPAEGPIRASNPCSEYMF-----------LDDTA-CNLASLNLLQFKDAKtkridiaDYEHAVRLWTVVLEVSVMMAQFPSRQIAERSYEYRTLGLGYANIGGLLMSSGIPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSFApnrdnmlrvirnhrraahgQSEGYEGLsvnpvALIHADCTDQDLVAHATAA--WDKALELGEKHGYRNAQTTVIAPTGTIGLVMDCdTTGIEPDFALVKFKKLAGG---------------------------------------------------------------------------------------------------------------
>UniRef50_Q97K72(4-665:987) Ribonucleotide reductase, vitamin B12-dependent n=2 Tax=Clostridiales RepID=Q97K72_CLOAB  E=4e-43 s/c=0.27 id=22% cov=56%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRTQASACFIISIEDKLlgsHSISEQYVTETKLFKGGSGTGTNFSTIRAKGEKLSGG-GISSGLMSFLKGLDRNAGAIKSGGtTRRAAKMLCLNVDHPEIMDYITWK---AKEEDKVKALgkmgydasfegeayetvsgqnaNNSVMLSDEFMKKVCNLKN----NPDETIELKGRVDSSVNKVEKI-----------------SNLWEAFNKSSWRCADPSPLFSDTLNAWHtcpggedgNFNADYNKINSTNPCGE-------YAFLDDTS-----CNLASINLykfydteNKTFDLEGYKHVIGLVQLLLEASIHWGQFPTEDVARKTHMFRTTGLGISNLAALLMVMGYPYDSEEGRAISSSLIGVLTGYSYYISSLMAKEVGAFEKYNinkehmlkvlrNSARAAGSIdtPFEKIGykplvvnhsileKEDLRYISSELKNSWNSALESGEKYGFRNAQVSVMAPTGTISFAMDCaSTSVEPFFSHvIYKKLSGGGYMTLTNPLIQEsLKHLGYSENEIEDITNYI----------------------------------------------------------------------------------
>UniRef50_C1TR30(36-828:994) Ribonucleoside-diphosphate reductase n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TR30_9BACT  E=1e-42 s/c=0.22 id=24% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TESQQLFACFVISVEDSIEGIFDSVKDAAVISKYGGGVGGNFGNLREFGSDIKgGTGGKASGPVSFMETWNTMGSVVVQGGRRRAALMGMLYDDHPDVERFMDAK----VEDGKLPYFNISVSVSDELLTKAAQGGDFHLRS-------------------------RADGSVAK-TVKAADLWNKLCRNAWRRGDPGVFFGDRANVDNILKKAPQwRIESTNPCvtgdtwvmtdegpkqavdlvgrpttllvdgkgheTEGFFSTgvKPVFELKTKEghslkltadhkvmvdvdgewswipagelsegsilrlhdhsgeekiskamfdslvpcGEEAVfdvqvpgvnafdanglyvhncgeqplpnytsCNLGSVNLeafvssessgEAVFDMDSFVDQVFRSVYYLDLVIDATSYPLERIADRTKMIRPVGLGLMGLADAAIMLGISYGSESFNRFCRSLGGTMASAALAATVRIVSEEGkdPFPEHRlvselmESFRCEAGLP-DAVDRWLERMDEGGFREllermrrtdtvpytlvntleallsaasvhkgDGMGLVREVLEalfsGRMRNSRRLSVAPTGSISMLLDASPGIEPNFAWSWSRKVMSSTGDGGYETREYFHRLmtaehkdefrrtggisdprFVTAYDI-GTDSHVEVTGIFAAVVDSGISKTVNL------PSEATVDDVRRVYEDCYRMGCKgiTIY----RDGSRSDQ-------------------
>UniRef50_B6IYQ9(669-942:1191) Ribonucleoside-diphosphate reductase n=1 Tax=Rhodospirillum centenum SW RepID=B6IYQ9_RHOCS  E=1e-41 s/c=0.64 id=29% cov=33%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CLLGSVNLAALVrdpftpaarlDREELARVVPLAVRMMDNVVDVSRFPLEAQEAEAQAKRRIGLGVTGLADALILCGVRYGSEAGVRLTEEWLRAIQVAAYRTSAALAAEKGAFPLFD-----------REAFLERPMVRALPP-----DVREAIAAQGVRNALVTSIAPTGTISLFAGNvSSGIEPVFAYEYQRAVLmpDGSRRtETVQDLAYRLYRERMGPDAPLTDAFVDaqslepaahlvMQAAAQRHVDSAISKTINC------PADLPFEAFKDVYRQAYELGCKgcTTY-------------------------------
>UniRef50_Q65357(1-207:216) Putative uncharacterized protein n=1 Tax=Mamestra brassicae MNPV RepID=Q65357_NPVMB  E=2e-38 s/c=0.79 id=24% cov=27%
----MYVVKRDGRLEQVSSSKLYQRIHRLCHDLNSqfVHPRAVSLKVIKGLSDNTTTEDIDIYAASVAATL-TYKHYDYDTLAGRLLVTNMHKYVDESFTKVVQELHKHNLV------SDELLSVTIKHSKIIEENIDMKLDLDYNYFGYQTLKNGYLIK--INEKVAETIQHMHMRIALGIFGD-----DIDSAIKSYKFLSRKMYTHASPTMFAAGTLTPQTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q96525(1-198:236) Ribonucleotide reductase RNR1 like protein (Fragment) n=6 Tax=Viridiplantae RepID=Q96525_ARATH  E=8e-35 s/c=0.76 id=25% cov=22%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GILQPDMWNVIPSD------RWDWAVLRDMISKNGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYSRXVLSGEFVVVNKhllhdltdmglwtptlknklinengsivtcllrYPDDLKAIYRTVWEIITXRQWVNWAADCGCNIDQSQGLKL-------TTWTNPTSQNSFVHFYTWKRVWKTgMYYLRSRAAADAIKFTVDTAMLKE---------
>UniRef50_Q122S1(686-961:1189) Ribonucleoside reductase n=3 Tax=Proteobacteria RepID=Q122S1_POLSJ   E=6e-30 s/c=0.49 id=26% cov=31%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FDFDAFGKSVTTQVRALDNVLDLTFWPLPQQQAESAAKRRIGVGFTGLGNALVMLCLRYDAPEGREMAARIAVCMRDAAYAASVALAKEKGAFLKFD----AEGYLAPGTFANRLPA-----------GLQQAIRAHGIRNSHLLSIAPTGTVSLAFadNASNGIEPSFSWMYRRRKRESdgsttdyavedhawrLYRELGGDVDRLPGYFVSALEMSAA-SHIAMMEAVQPFVDTAISKTVNV-PVDYAYDDFKG-----LYQQAWRARLK----------------------------------
>UniRef50_C7LZ05(762-1094:1331) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7LZ05_ACIFD  E=1e-23 s/c=0.34 id=24% cov=37%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASINLLAYldedgnFDVEGFRHTARVLITAQDILAGNADYPTPRIAETSRAYRQLGLGYANLGAMLMALGLPYDSDGGRAYAAAVTALMTGAAYERSAELAERLGPFAGYaddAESMLRVLGMHRDALAKvdGAPEAIVEAARASWDMAIARASEVGVRNAQASLLAPTGTIGFLMDCdTTGIEPDFSLVKYKTLVGGGTMKIVNqtVPRALRTLGYPEHEIDQITAYlaehdsivgapglkpeheavfacavgeypisptghLAMMGAVQPFLSGAISKTVNLPSTS------TVEDVEQTYLDAWRLGIKavALY----RDGSKVGQPLSTTHEEDSE--------
>UniRef50_D0MFS7(763-1090:1354) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MFS7_RHOM4  E=4e-26 s/c=0.38 id=24% cov=35%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASLNLRKFqredgsFDVERFRAAVRIFITAMEILVDNAGYPSEKIAQNSHDYRPLGLGFANLGAMLMAMGLPYDSDEGRAVAGAITAIMHAEAYARSAEIAaiEHIGPFPGFEKNREPM-LEVMRMHQAAVEDIHLSCPAYLKEAARESMArmvalgeRYGYRNAQATVLAPTGTISFMMDCdTTGIEPDIALVKYKllaGKGDGMFKivnNTVPIalrrlgyseeqikdilaYIEENDTIEGAPHLKEEhlpvfdcafkpykgqrfihyMGHIKMMAACQPFISGAISKTVNMPEH------VTVEEIMDAYIQGWKLGLKalAIYRENSK--------------------------
>UniRef50_Q9DWE5(576-1027:1064) PR45 n=1 Tax=Rat cytomegalovirus Maastricht RepID=Q9DWE5_RCMVM   E=4e-22 s/c=0.24 id=23% cov=45%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLYAVNVPQFFWERyVEEGasGRWQVFQKSECKSLCRV---DEKGFRTAYERLELEGNglslSPWWVVRHLDacvalgntavVYPYNLKSAMvgETGRLLLC--------GPelslvCNSFLGVFPENkiDVCLEncLLEGSGADDAAAATEGEVPV-------LGHevFFSFRSLRVLVRDAVvignVLMDAVIRDNVF---GAGDVMCLYRPLQLRVLGFHAVLGRLGLLYTDDASVLLGRRIAEFVHYAAVRASVDLcvhgAE---PFPKFSRSLFATGRLYPDLFDDPLQETSSLPAGH-WAQLREDVVRYGVRNSAFVCGGLGEESANVAGTTPGMFPRAYNLSLEPSPllaaprdrcLGEALRVAEDLrldlpnasdrsllalvgnqrvylpvvnrylaeiprsravlavrmgyaaglyagveeeDEDRASLETGW-MTSQEAVLKMAVDRQPYVDQGQGLPLF---------------------------------------------------------------
>UniRef50_Q3B5C1(835-1085:1521) Ribonucleotide reductase family protein n=9 Tax=Bacteria RepID=Q3B5C1_PELLD  E=7e-22 s/c=0.43 id=23% cov=26%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASLNLIHFVDEEsghvkinELRHAAALWTVVLEISVLMAHFPSPDIARLSYEYRTLGLGFANLGTVLMVLGIPYDSPKALALAGAISAIITGQAYVTSAEISRDLGPFDGYQaNSKemlrvirnhrrAARNESEEEYEELSVKPRGIDSEYCPkelfeaagsvWDEALQKGKKYGFRNAQVSVIAPTGTIGLVMDCdTTGIEPEFAIVKFKKLAGGGYFKIVN--------------------------------------------------------------------------------------------------------
>UniRef50_B3QY00(831-1025:1966) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Bacteria RepID=B3QY00_CHLT3  E=1e-14 s/c=0.43 id=25% cov=21%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASLNLIHFvnektgdVDTDALRHAARVWTLTLEISVLMAQYPSPKIAQQSYDYRTLGLGFANLGSLLMVSGTPYDSPKALAVAGAISAIMTGEAYATSAEMAADIGAFPKFAHNRDAMLRVVRNHRhaahnapKEDYEDLSVVPMSLDpahcpkklckvagetWDRALKLGEKHGFRNAQVSVIAPTG------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9XD73(8-333:599) Vitamin B12-dependent ribonucleotide reductase (Fragment) n=15 Tax=Actinomycetales RepID=NRDJ_STRCT  E=6e-18 s/c=0.29 id=22% cov=35%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASLNLMKFlrddtasdgasgaggnmsLDAERFAKVVELVITAMDISICFADFPTEKIGETTRAFRQLGIGYANLGALLMATGHAYDSDGGRALAGAITSLMTGTSYRRSAELAAVVGPYEGYaRNADAHKRVMRQHADANTAAQRMDDLDTPVWAAATEawqDVLRLGeqnrFRNAQASVLAPTGTIGLMMDCdTTGVEPDLALVKFKKLVGGGSMQIVNNtvpkaLKRLGYQPEQVeavvahiaehgnvidapglkpehYEVFDcamgeraisPMGHVRMMAAAQPFLSGAISKTVNMPESATVEEIEEIYY------EGWKLGLKAL--------------------------------
>UniRef50_C9LEN5(34-500:775) Ribonucleoside-diphosphate reductase n=1 Tax=Prevotella tannerae ATCC 51259 RepID=C9LEN5_9BACT  E=5e-15 s/c=0.18 id=22% cov=42%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHVSLSTPMLAGLGNPHRQapVSDAFTIGFGPKAYSYNDllqADEEEVYLLRRGAALGHDLSRIYPAQLQTEQSEKATPDVVsaleRYARSRQEAARltAC-------GAITLSLSIKHPDAEAFID----AGARMRTTAGVNCCLLIDDDFMYAVAKGESYRQQFPVDA-----------------------ESPLLATNIDARRLWEKLLRKAMRNEAPEIHFSD-----NMLKEQLAGCYAG---------ARPQALAATLNATIPLATydssrLLTVNLysyveqpfteQAIFDHKLFRRHLFLVQRLADDLVDIEEEKIdsmlqniadaevpaeakmieqklwEKVRRHLLTYRPTGLLLTGEAETLAALGLSQDTPAAGAHTRALKQSLAIATCESTVKMAEERGAF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_O66503(2-801:801) Ribonucleoside-diphosphate reductase subunit alpha n=1 Tax=Aquifex aeolicus RepID=RIR1_AQUAE  E=0 s/c=1.08 id=33% cov=97%
----MYVIKRSGRKEKLDINKIRIAIKFACEGLN-VDPLELEADAQIQFRDGITTKEIQQLLIKTAAEKVSAERPDWTYTAARLLLYDLYKDVahlrgyslrddlgkYKPYNRKNFYSFVKEYVEKGIYGEYLLENYSEEDFNKLANYIKPERDLYFTYTGIKILYDRYLVRDE-EGRVIELPQEMYMLIAMTLAVPEKPEERLKWAKKFYDVLSEHKVTVATPTLMNARRPFTQLSSCFVLTVDDDLFDIFDNVKKAGMISKFAGGLGVYLGKIRATGAPIRKFKGASSGVIPVVKLINDTMTYVDQLGMRKGSASITLDIWHKDILDFLEVKTNVGDERKKAHDIHPAVSIPDLFMKRLKNREDWTLIDPYwarqyitrkiydgkykEVKPLPGSHYyvgikedgtqdilepkgledFYGEEFEKWYLELEENlPSYAKKKVNSFELWKRLLTVAFETGEPYIFFRDEANRKNP-NKHTGMVYSSNLCHEIVQTMSPSKhekpvldpetgeiTYKKEAGDLPVCNLGSVNLGKVHTEEEIKEVLPLLVRMLDNVIEMNFYAIPEAEYTNKRYRAIGIGVSNYHYCLVKNGIKWESEEHLKFADKLFELIAFYALKGSLELAKERGRYKLFDGSNWSKGILFGRSVEEIEENSRQNGNNLPWRELAEEIKKYGIRNAYLLALMPTGSTSLILGATPSIDPIFARFYKEENMSGILPQVPPEVDRFYWHYKTAYTI-DHEWTIRAAAVRQKWIDQAQSLNLFVD-----PQNIDGPRLSRLYELAWELGLKTIYYLRSRSAMDI-----------EECEACSV--
>UniRef50_C5LWW8(3-765:1504) Ribonucleoside-diphosphate reductase n=4 Tax=Eukaryota RepID=C5LWW8_9ALVE  E=0 s/c=1.10 id=30% cov=93%
----MYVIKRNGQKADVQFDKITKRIRPLTRGLNEdyVDVTQITQKVAEGIYPGVTTTELDSLAAETCAYM-SQVHPDFSTLAARIAVSNLHKNTHESFSETIteLYNITDSRGRSSPLVSEEVYNIVKMNADKLDKAIDYDRDFDYDYFGFKTLERSYLLKRPSDKTCIERPQHMIMRVAVGIHGD-----DVDAAIETYALMSTRVFTHATPTLFNSGTPHPQMSSCFLLSIkEDSIEGIYDTLKQCAMISKTAGGIGVAITGIRATESYIRGTNGFSNGIVPMLRVFNDTARYVDQgGGKRKGSFAVYLEPWHADVFEFLDLKKNHGKEEHRARDLFYALWIPDLFMKRVMANGDWTLFCPNEAPGLQDTY---GEEFEALYEKYEKDG-IGRKTVKAQSLWFKILESQQETGIPYMLYKDSANRKSN-QKNLGTIRCSNLCCEIIEYTS--------SDEVAVCNLASIALNMFvdkktrtYDFDRLHRVAKVVTKNLNKVIDRNYYPVPEARKSNMRHRPIGIGVQGLADAFLLMRYPYESPEALKLNNDIFETIYHAACEASMELAKRDGPYETFQGSPASEGILQFDMWDVIPD-----SGRWDWASLKEEIKKNGMRNSLLIAPMPTASTAQILGNNEAFEPYTQNIYVRRVLAGEFVQVNrhlvddlmelglwndeikdkiirkkgsvqgveEIPSEIQDLYKTVWEIK-QKKILDMAAGRGPYIDQSQSLNIHM-------TNCTNAKLSSMHFYGWKLGLKTgQYYLRTKAAADAIQFTLD---------------
>UniRef50_A4XD09(114-859:909) Ribonucleoside-diphosphate reductase n=44 Tax=Bacteria RepID=A4XD09_SALTO  E=0 s/c=1.06 id=28% cov=93%
-RQVMGVRKRNGDTEPVDVNKIVRAVERWVADLDEVDPLRVATKTISGLYDGATTAELDRLSIQTAAELIG-EEPQYSKLAARLLAAYVDKEVRGQ-QVASFSQSIRYAHGLGLISDE-TAAFVSRNARKLDDAVDPAGDLRFEYFGLRTVADRYLLRHPQSRLVVETPQYWLLRVACGLSGTPAE------AIGFYRLMSSLAYLPSSPTLFNSGTRHTQMSSCFLVDSPrDELDSIYQRYHQVAKLSKFSGGIGIAWSRVRGRGALIRGTNGRSNGIVPFLKTLDAGVAAVNQGGRRKGAACVYLEPWHPDIEEFLELRDNTGEDARRTHNLNLANWLPDEFMRRVEADGDWSLIDPSEAPELPDLY---GEEFDAAYRVAEKKAV---RTVKARDLYGRMMRTLAQTGNGWMTFKDRSNTLSNQTGEPGnTIHLSNLCTEILE--------VNNDAETAVCNLGSVNLGAHvtadgVDWEKLRDTVRTAVVFLDRVIDINYYPAEQAAASNPRWRPVGLGLMGLQDAFFTLRLPFDSAEASELSTRVQEEIFLTALETSAGLAERFGPHPAYAQTRAARGDLHPELWG----AVPSQPQR--WAGLKARVGEHGLRNSLLVAIAPTATIASIAGCYECIEPQVSNLFKRETMSGEFLQVNtylvgelkarglwtasirdqikraegsvqglaELPAEVRELFRTAWELP-QRALIDLAAARAPYIDQSQSLNLFLAAP-------TIGKLSSMYLYAWKSGLKTTYYLRSRPATRIQQ-------------------
>UniRef50_Q9QAL9(5-797:848) Ribonucleoside-diphosphate reductase n=2 Tax=Shrimp white spot syndrome virus RepID=Q9QAL9_WSSV  E=0 s/c=0.99 id=27% cov=95%
-----FISKRNGTKQEISLEKIIKRIENAClpvnqyvpkLDKNAINPQELASHIMDRLPATISFQEMDDFLADYAKTKI-VDHPDFGKLAGRFICSNIHKNTkeWNSFSATTQKLRHAIHPGTGKPASVVNDTYYENvmaNAEILDAVIDYKMDYLFTCFGLRTLEYSYLIKigsptDRKKRILVERPQDMIMRVAVGIHG-----SDIKSVIETYDLMSRHYFTHASPTLFNCGTVTPQLSSCFLLGLqDDSIEGIYDTLKEAAIISKTAGGLGIHFHDLRAKGSPISSWSGTHPGLMAFLQIFNVSVKKVSQGGdKRRGAAAIYISDWHLDVKDFIDCRKNAGNEDLRTRDLFPAIWVSDLFMERVKAGKNWSLMCPHECPGLSDVH---GEEFKALYEKYEAEGK-GKEVVKARALFDQINSARIETGTPYVCFKDTINRKSN-QENVGIIKSSNLCTEIVQYS--------DSEETAVCNLASIAVNKFvkyspipslrpyVDYREMKRVVKIMTRNLDKVIDVNFYAVDKTRISNMKTRPMGLGVQGLADLFFKLRIPFESEEAALINKRIFETIYYGALEASCEIAKEKGeTYELFEGSPLSKGIFQFDMGKeniKNRDIYFNSLPIHDWEQLRRDIMKYGVHNSMFVAPMPTASTAQILGNSESFEPLTSNMYNRNVLSGSFQVVNEYvireliklgewnsvtkqrimasggsiqtlpniPKSTKELFKTVWEI-NPRTTLDMAIQRGMFVDQAQSLNLFVEEPE-------LSKVRSMTMYAWEKGIKTLYYLRTKGAARAVQFTVDKNVLQE---------
>UniRef50_UPI0001AF06E2(1-759:790) ribonucleotide-diphosphate reductase subunit alpha n=1 Tax=Acinetobacter baumannii AB900 RepID=UPI0001AF06E2  E=0 s/c=1.03 id=30% cov=96%
----MNVTKRNGATEPFSPSKIEKAVNWAVDG-TSVESQEVIDKAILLIYDGIKTSDIQQALIKGAAKLVSATKADASLVSARLLLLDLYKTVCGVNGKVSgggfQYPHIKDYLEKGVSLKLLDPELLNYDLERINAAIKPERDLSFHYLGLDTLADRYFIRanrdirleketGNMSGNIIELPQHFWMRVAMGVALKEKPEIRTSVALAYYELYSKLEYVSSTPTLFNAGTLHPQLSSCYLNQVSDTIaadegdnrfASIFGAIEETALLSKFAGGIGTDWTPVRGENELIFGTNGISSGVVPYIKVQNNTAVAVNQGGKRKGSVAPYLEAWHPDFMAFCELKRESGDDRRRAHDVFPAAWVPDLLIERKEDpNAMWSFFSPKRFPELHELY---GEDFVKRYEELEAAGEYDFQ-LPAIQVWRHLLTNLFETGHPWITYKDECNRRNP-QQHAGVIHHSNLCTEITLNTS--------KDETAVCNLGSINLSQVMSapnpLERLREVIRLAIRNLDSVIDVNYYPSDRASNSNFKHRPIGLGVMGYYEWLVKQGVDFESEEHLKQADALFEAISYFAIEASADLAQERGSYPSFEGSNWSKGILPIDNAKLMEDGKPffDQPRRFDWEALREKVKK-GMRNSNVMAIAPTATISNIAGTTQCTEPPFLLEYFKSNLGGTYQVVDPAIAHVGDKYHLLKESYYVDQlyIIKAAAVRQKWIDQSQSTNLF------AKQGTTGRDLDLWYTTAKKLGLKTTYYLRNQSDAEKSASMRTKVIAE----------
>UniRef50_D2E8G7(3-781:833) Ribonucleoside-diphosphate reductase n=1 Tax=Anguillid herpesvirus 1 RepID=D2E8G7_9VIRU  E=0 s/c=0.98 id=28% cov=93%
---NFSVRKHSGRTEMWSTKKMLSKLESLSYGLNTdfVDLDRLVTATMDGLYDGITTKELDDVMARTAAGFTSYHF-DYSLLAGRIVVNSIHKYTVGNFLQGAVL--LQNMDETKPHVTDELVAVARKYENQIQGAIDYSRDYTFNFFAIRTLERAYLLK--VNERVMERPQHLFMRIAIGIHGF-----DLESVLETYRCLSEKRFSHASPTLFHAGTNFAKLASCYLVTLaDDSIAGIYSTLQECAQIAKCSGGIGAAISNVRAEGSAINSTNGTANGLVPMLRVFNAMTRMVDQGGnKRPGAMAVWLEPWHADIAAWLDLKKNLGDDGIRARDLFYGLWISDLFMERVKDDQMWSLMCPKKCPGLMDVYGSD---FVALYTKYESQGMYVKQ-VEARELWTHILRSQMENGMPFMMYKDSCNRKSN-QQHVGVVKCGNLCTEIVEVSEPHRP--------AVCNLAAVCLPtcvacecgirqasrtevassassavqacedptcrKSFDFGELGRLTEVLVKNLNRVIDKSDYAFDGANHRNSQDRPLGIGVQGLADVFAMLGLAFDGTEAARLNVQIFETMYYHAMAASCKLAEEDQPYPTYKGSPVSQGIFQFDMWGVKPSAMH------DWTSLKRRVQKYGVRNSLLLAPMPTASTAQIFGNNEAFEPFTNNLFTRGVLSGDFQIINPhlvrelirlgmwgeetrmrlmadngsirtwedVPQHTRDVFKTVWEIS-QKTIINMAADRAPFIDQSQSLNIHMADPN-------VSKLSSMHMYGWQKGLKTgMYYLRSRPAVNAIQFTVDKT-------------
>UniRef50_C8WK91(126-844:845) Ribonucleoside-diphosphate reductase n=27 Tax=Bacteria RepID=C8WK91_EGGLE  E=0 s/c=1.01 id=27% cov=88%
-------------------------------------------------------------LVKAAVELTTQEAPRWEIIAARLLMVQFDRALAERLAArhiETFAQKVAFLTEEGLYGDYILQHYTPAELDEAAGFIDLSRNDLFTYAGLQLLLDRYVIRTH-QGAPLESPQEMFLGIALHLAMEERASERMGWVRRFYDMLSTLKVTMATPTLSNARKPFHQLSSCFIDTVPDSLDGIYRSIDNFAKVSKYGGGMGLYFGKVRASGSAIRGFDGAAGGVIRWIRLANDTAVAVDQLGMRQGAVAVYLDAWHRDLPEFLALRTNNGDDRMKAHDVFPAVCYPDYFWQQARDNieGDWYLMCPHEILTVKGYALEDcyGEEWTRKYLECVADARIKKRAIPIKDVIRLIIKSAVETGTPFTFNRDAVNRANP-NKHRGMIYCSNLCTEIAQNMGAIEQLEqriedvdgeqvvvtvTKPGAFVVCNLASLSLGHIdmDDPHELAHVTESAVRALDNVIDLNFFPVPYAEINNRQYRPIGLGVSGYHHLLAKSGIRWESEEHLAFAERVFGDVHYAAVRASCAIAREKGAYGFFEGSGWQTGEYFRDRGLTDG----------RWAELARDVAEHGLRNGYLLAVAPTSSTSIIAGTTAGLDPVMNRYFLEEKKNGLMPRVAPELSMDTFWYYKNAHLIDQTWSVRACGVRQRHIDQAQSMNLYI------TNEYTFRRVLDLYLLAWEEGVKTIYYVRSKS------------LEVEECEVCS---
>UniRef50_Q2P8D3(64-831:832) Ribonucleoside-diphosphate reductase n=66 Tax=root RepID=Q2P8D3_XANOM  E=0 s/c=0.92 id=26% cov=94%
------ITKEAGnRKIPFEPERLERAIDQIHAEFPQLDVADYKRSVfgFVERKDSVNADDLVDHLIREAEARVDLTTPEWEHFAARLYLRRLYKRASRnrfydaSQKYGSFVGLQESLADRNVYSNDILRRYSKDELIEAGKMIEPERDKLFAYNGLYLLATRYLATDSSRG-VFELPQERWLTIALYLMQDEigtgkgSRERRMQLVGEAYWALSNLYMTVATPTLANAGKVGGQLSSCFIDTVDDSLQGIYDSNTDVARVSKHGGGVGAYLGYVRSSGSAIRGVSNSSGGVVPWIKQLNNTAVSVDQLGQRKGAIAVYLDIFHRDIEAFLDLRLNNGDQRLRAHDVFTSVCIPDLFMEAVERRGDWYLFDPHEVKRVKGWYLQDFYDekkgdanssFRRKYEEVVADERITRKTVKAIEIFKRIMVSQLETGNPFMFYRDEVNRKNP-NKHEGMVYSSNLCTEILQNMSPTRMMQEiisgnqivttkKAGDFVVCNLSSINLGRAITVqadqadllgaDVLERLIPIQVRMLDNVIDLNQLPVPQATITNQKYRAIGLGTFGWHHLLAQKAIHWNAKEAEDYSDELYERINYLTIQASMELAKEKGTYSVFRGSDWHNGE-----YFRARDYNSPQ-----WLELSAQVAVNGVRNAWMLAVAPNMSTAQIAGSTASIDPIYSAFYYEEKKDFRRPVAAPGLSlDTWPYYEKGAYKVDQFASVRQNARRQRHVDQSISFNFYV------PSTIRASTLLDLHMTAWREGLKTTYYVRSND-------------------------
>UniRef50_A2PYM5(3-742:742) Ribonucleoside-diphosphate reductase n=4 Tax=Myoviridae RepID=A2PYM5_9CAUD  E=0 s/c=0.91 id=28% cov=95%
------VIHTDGSRTPYDANRAIEVINWACEGLE-VDPDKLSRRLSRRFNADITTEEIQNGLIRTAAELADLQYPDWLKVSGRLRMWDWRRKVkaRRGYLYGNYPVAFEYLRSEGLYEGDLikkfLDTYSADDIAEAGTWIDPERDMRFDISGADLLTARYLLEG-------ELLQEMWLTQALLLSMLEPAHERMTFAHKAYDLLSLGKISLATPLMSNLRQADGSLSSCHIIDIDDSRESIFDNISQLAAMSANGGGVGVRISKVRARGSRIRKKKGASGGVCPWIKIINATIVATNQRGVRAGACTVGIDVWHADLLEYMDLRGDAGSEHTKARDILLQFIISDEFMRRVILDKDWYLVCPTEIKNVFGYQLADmyGDEFTNAYHVIEAYinssapPLDVVKKVSAKAIWKKMLMLLLETGTPYVAFKDRINALNP-NKHEGIIGGVNLCVE--------SYSLFNSSYSHCCMLLSLVLPRIAD-DEMADVSRTAVRLLDAACDLTTSPTPEARAHVNRYRTIGVGVMGLADWLAIRHLRYQD---LNLIEKLFEDICFYTTQASVELAEERGAYPAFPGSEWSKGLILGGRDKEWVRDNSTDPER--WYALMERIIVSGIRNSHILATAPNSSTSLVQGATASFLPVFSRLTIDKNGAGINTIVPLYIKEaFHFYQESRYTHPSV--VVSAAATIQKWVDTGLSTELlfNFNEHAYGFDYvATAKDLNDVYMQAWREGLKTVYYVRS-----MWQDTVTEKSECHSCAS-----
>UniRef50_B8HJ14(68-724:726) Ribonucleoside-diphosphate reductase n=158 Tax=root RepID=B8HJ14_ARTCA  E=1e-166 s/c=0.89 id=25% cov=82%
------------------------------------------------------------------------------------------------------------LVENRYYEPELLEQYGFEFVKSLFQRAYKKKFRFETFLGAFKFYTSYTLKTFDGKRFLERYEDRVTMVALGLAA-----GDKALAEKLVDEIIDGRFQPATPTFLNSGKAqRGELVSCFLLRIEDNMESISRAINSALQLSKRGGGVAFALTNVRETGAPIKQIENQSSGVIPVMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKKDEDMYLFSPYDVEKVYGMPFSDI-NVTEKYYEMVDDARIKKTKIKAREFFQTLAEIQFESGYPYIMFEDTVNRANPIE---GKIIMSNLCSEILQVSTPTTYNEnlnyevDGIGKDISCNLGSMNIAKAMDGGDLGATVEIAIRALTAVSDqSNITAVESVARGNRMSHAIGLGQMNLHGFLAREHVYYGSPESIDFFGKYMAAVAFHAIRASNLIAKERGvTFDGFERSKYASGEF-FDKYVTRSWLPTTErgqelfakfgitlPTIADWEELKASVMEHGIYNQNLQAVPPTGSISYINNSTASIHPIAAKIEIRKeGKIGRTYFPAPYLtNENLEYYQDAYEIGYEK-IVDMYAAATEHVDQGLSLTLFFKDT------ATTRDINKAQIYAWKKGIKTIYYIRLRQMA-------LEGTEVTGCVSC----
>UniRef50_P0A5W9(72-723:725) Ribonucleoside-diphosphate reductase subunit alpha n=348 Tax=Bacteria RepID=RIR1_MYCBO  E=1e-165 s/c=0.89 id=25% cov=82%
------------------------------------------------------------------------------------------------------------LIRENYYEREVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAA-----GDTALAELLVDEIIDGRFQPATPTFLNSGKKqRGEPVSCFLLRVEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFADI-SVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPID---GKITHSNLCSEILQVSTPSLFNEDLSyakvGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRALTAVSDQTHIkSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTVLYHALRASNRIAIERGThFKGFERSKYASGEF-FDKYTDQiwepktqkvrqlfADAGIRIPTQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKeGKIGRVYYPAPYMTNDNlEYYEDAYEIGYEK-IIDTYAAATQHVDQGLSLTLFFKDT------ATTRDVNKAQIYAWRKGIKTLYYIRLRQMA-------LEGTEVEGCVSC----
>UniRef50_Q6R7H4(70-834:835) Ribonucleoside-diphosphate reductase large subunit n=1 Tax=Ostreid herpesvirus 1 RepID=RIR1_OSHV1  E=1e-159 s/c=0.74 id=26% cov=81%
-------------------------------------------------------------------------------------------------------------------------DFVNEHGARLDGMIDDVRDYSHNYMGITGLLNGVAIK--VNKKLYERPQYVFMRVAMAM-TDLSSETALEDIWQTYMLISGQCLSMASPVLFNGGTSSSNTASCFLLDMGDNMVSITKKVAQTMTLIAKNGGIGINFSKLRATGSKI-GMAGKSSGIGGKLNLFDRVAQSVDQGeNKRPGAIAGYLTDWHADMYDWLYSRySGSGNEVNKRHVLNMGLVMSDLFMERVENDKEWSLFSPNDVVGLEELY---GEKFVRAYRAHEANPKIKRTTVSARKLFSDIANMMWSTGEPYILFKDAVNERSNH-KHLGTIKNSNLCCEIVQY--------CDTNEIAVCNLATICVSNFVnvetgeiDFEGIADAAGVACKGINNLIDKQNYDLgneqlmrladertEEVVevngikfdakynlvsYSNLKHRPQGIGMQGLHDVFMKLKIPYDSEMAFRLAALIQEAIYYGAVRESVKIAEEKGPYPSYywDNNTHREGKLQFDFLEGFDRDRDLTHELFNWREVLKKFEKFGINNSVVTAQPPSASSSQLNDNVESIEAITSNRFTKGIKDGKFIIINKhlqkdledlgmwdaqmvgdieandgsiqnierIPKNIREIYKTAREI-DHKAVVKICAAIQPFIDQTISKNMFVPK----NVDNPVQLIMENVILGHKMKLKTgMYYTRGIPAMKqqnfgkmnfQDKDIGKPVPELVDCEACS---
>UniRef50_B1V8V8(207-856:856) Ribonucleoside-diphosphate reductase n=61 Tax=Bacteria RepID=B1V8V8_PHYAS  E=1e-151 s/c=0.83 id=23% cov=83%
----------------------------------------------------------------------------------------------------TLKEKLTFLQTNEYYETDFLSQYNEQQIKDIYKIAYQKQFRFSTFMGAFKFYNDYALKSRDKKYYLETYEDR-----LCVNALYHAQGDFEIAKRLIKSLINQDFTPATPTLLNAGKKHrGEFVSCFLLEAGDSLNDIARINEFSMQLSKIGGGVSINITNLRAKGESIKGIKGVCKGVVGVCKLLDHSFRYADQMGQRTGAGAVYLSVFHADIEDFLSTKKLNADEDVRVKTLSLGVIVPNKMIELARKNEVMYTFYPHTVFLEYEKNFADIAvNMDYWYDILVSNPKVRKKAIQPRQLLELIARMQGESGYPYLMFCDNVNQNNTSHLQ---VKFSNLCTEILQPtitshyTDYNHTQEDKIGMDVSCNLASGHMSNMINNNTIKETVFMAMEVMNTVSMKTNINyVPAVAKANRLNRSVGFGIMGHHGFLAQNYIAFGSEENKDLIDVFFNAINYYSLLHSCQKAKKTGqKFYLFEKSHYADGsyfkgrgeILPKTDKIKKMFANIPLPSEKDWQQLKKDVQQFGLFNSHRLAVAPNGTIGYIMGTTPSLTPIKQLVEERTYGNSKTYCPMPGLKETSFMYVTAYKM-NKYQLIDVIATAQKHVDQGISFEL------GITSDITTRELQRYYLYAHHKGIKTLYYTRTQK------------LKVDECEACGV--
>UniRef50_Q2RP92(10-575:786) Ribonucleotide reductase large subunit n=1 Tax=Rhodospirillum rubrum ATCC 11170 RepID=Q2RP92_RHORT  E=1e-140 s/c=0.89 id=24% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHAGAGTDRRvTLINCFVnMIVPDRMDGIMEALTRAALTMQQGGGIGTDFSTLRPRGAKVRRTGSVSSGPLSFMEIWHAMCGTIMSGGARRGAMMGTMICDHPDLPAFITAKAQAG----RLTNFNVSVLVTDAFMRAVDEDATWDLgfsVPPADPARLVAVTERNGEPW------------YVYERLSARALWEKIIRTTYDHAEPGVIFIDRVNERNNLA-YCETISCTNPCGEQPLPP------------NGDCNLGCVNLAvlvrdpftpqARFDDARLAEVAAIGVRFLDNVLDVSNFPVEDQAKEAQAKRRLGLGIMGLGNALQMLGLRYGSPAAIAETRRIMALLRDAAYRASAELAGERGPFPLYDR----------------DQLLARPFIQELPDDLRAKIAEQGLRNGVMLTIAPTGTTAiYYNNVSSGLEPTFGWRYFRKVLrpDGghdEFAVIDAGFESwcrtrgldpatapltgLPDSMVTALELSVED-HLRMQAACQEFIDASISKTINC------PADMSYDSFAAVYKLAYEMGCKgcTTY-------------------------------
>UniRef50_C6JQA3(11-547:754) Putative uncharacterized protein n=2 Tax=Fusobacterium RepID=C6JQA3_FUSVA  E=1e-120 s/c=0.81 id=24% cov=59%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSNCYVIaPPEDNLESIFDTAKKLARTYSYGGGCGVDISKLRPRGSEVNNSAKHTTGSISFMELYNLTTDIIGQKG-RRGALMISIDVNHPDVSEFISIK----SDLNKIQKANISVRVDANFMKAVIE----------------------GMQFVTEFL-VEDTGEVVTKEIDARKLFKELARQNWKFAEPGILFWDRISKWNLLSEDEEFEYAgTNPCAEEPLPAG------------GSCLLGSLILPTFvegkeFNFDRLAKVVQKSVKALNDVLDegLPLHPLEEQRESVRDWRQIGLGILGVGDLLIKIGMKYGSPESLEFCDKIAKVIVDNALKASALLAKDFGAYPKYKADKVLKSEF---------------LLENASIETLELIEKYGLRNSQLLTIAPTGSIGTMLETSTGIEPNFAFSYVRKTESlhgedvfyKVFIPIAKKYmeennitdeEDLPEYFVTAQSLNPYDR-IKMQGVWQKRIDASISSTINLV------NKVSVEEVEKLYLEAWKNGLKgmTIY-------------------------------
>UniRef50_C1XXN0(8-774:1014) Ribonucleoside-diphosphate reductase n=1 Tax=Meiothermus silvanus DSM 9946 RepID=C1XXN0_9DEIN  E=1e-118 s/c=0.56 id=22% cov=68%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFRRVADWVAGAEKPEARAYWSEEFFRLMASKRFCPGGRVLAGAGTRHGNVLNCFvqgatendpssfngvlevakklalvtkvgggngvnldpypprhggagkaagprrtvrgfaylradhpdvqdfiqgmmrppinpdgekepitvrnwtrvvyglvspelaalarrhgvltvrerpqgVLEVPDDMGGIIDTARDAVAMAGKGQEPHVDFSLLRPEGTPIKGSGGTSSGPVSFlLEIFDNflewgnlgaeksgpvatlryvyspVLRVVRQGGTRRGAGMATLSIDHPDLLDFLTAKDlDREAAEGDISTFNISILVTEAFWNTLQADGLWA-VEPAEVPGKYYPYLVQGEytgalpELPDREVDGARAIPVYEGKVPAKWLWHEIAWHAWATGEPGLIFVDRINELSALKHLGEryRIRATNPCGEIPLTVGEP------------CDLGAINLAAYvredktFDYATFRADVRTCIRFLDNVLDVNVFALEDNRIASQSLRRLGLGVMGLADALIKMGLPYSSEEGRQAVAKIMNAMREEAILASERLGEERGVFPIYAQ--------HPEKFPEIRPR----------------------RNVAVLTVAPTGTTSMLMGVSSGIEPMFSPFMWRRIGGqykallhplfveqmekypptppfekegawdwdklieaiqahhGSVRGIEGIPTEIQAVFEGAHDVPPLD-HVRMQGVVQRAFDafglaaNSLSKTINL------PNQATVADVEAAYTEAYLTGCKgiTVY----RDGSRDLQ-------------------
>UniRef50_C9L7Y1(13-549:763) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Blautia hansenii DSM 20583 RepID=C9L7Y1_RUMHA  E=1e-117 s/c=0.79 id=21% cov=58%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSNCYVVePPEDNIESIFDCAKKLARTYSYGGGCGVDISKLAPKGARVTNTAKETSGSVSFMDLYSLVTGLIGQNG-RRGALMISIACDHPDLEEFIEIK----SDLDKVTKANISIRITDKFMLAVKMRKPFVL------------------SFTR-----EETGETIRKEIDAYSVFHKLCEMNWDYAEPGMLFWDRIENWNLLSADKEFSYAgTNPCAEEPLPAG------------GSCLLGSINLSEFvtenktFNFTDFKKTVDIAVRALNIVLDegLPLHPLKEQRESVRDWRQIGLGIFGLADLLIKIGIKYGSPESIDLCDMIGHAMAYQAIMTSNSIAIEVGSYPKYKPDAVKQSPFFTEHIDELY---------------RENISEIGLCNSQLLTIAPTGSLSSMLGVSGGIEPVYANYYTRKTESlhGhdeyykvytpIVKKYIDEYglkddSELPDFFVTAQTLNYKER-IDMQSIWQRHIDASISSTVNV------PNNFTVKDTEDLYLYAWEKGLK----------------------------------
>UniRef50_Q5L9C8(10-696:882) Ribonucleoside-diphosphate reductase n=26 Tax=Bacteroidetes RepID=Q5L9C8_BACFN  E=1e-116 s/c=0.62 id=24% cov=69%
--------------------------------------------------------------------------------------------------------------------------------------------------------NKYAVKDSFGNIYEKSPKDMHWRLANEVARIEAKYPNALSSEQLFELFDHFKYIVPqGSPMTGIGNDYQvaSLSNCFVIGIDgsaDSYGAIIKIDEEQVQLMKRRGGVGHDLSHIRPKGSPVKNSALTSTGLVPFMERYSNSTREVAQDG-RRGALMLSVSIKHPDSEAFIDAKMTEG----KVTGANVSVKLDDAFMSAAVEGRKYTQQYP-----------------------IDSDHPTTVKEIEASNLWKKIVHNAWKSAEPGVLFWDTIIRESVPDCYADLGYktvSTNPCGEI--PLCPYD----------SCRLLAINLysyvvnpftkDAYFDFDLFHKHVALAQRIMDDIIDLelekieriiekidQDPENEEVKHTERGLwekiykksgqgRRTGVGITAEGDMLAALGMRYGTEEATEFSEKVHKAVALGAYRSSVDMAKERGAFDVYDS-------------EREKNNPFINRLREADPALYEDMKKYGRRNIACLTIAPTGTTSLMTQTTSGIEPVFLPVYKRRrkVNPNDTNVRVDFVDETGDAFEeyivfhhkfvtwmeangydpakryTQEEIDelvakspyykatsnDVDWLmkVRMQGKIQKWVDHSISVTINL------PNDVDEELVNRLYVEAWKSGCKgcTVYRDGSRSG------------------------
>UniRef50_P50643(244-833:835) Ribonucleoside-diphosphate reductase large subunit n=21 Tax=Herpesviridae RepID=RIR1_SUHVK  E=1e-113 s/c=0.70 id=25% cov=70%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YFRALATQAIVPATPLMLFAGRARGSLASCYLLNPLPrtTEEAVRAITDEVAPILLRRGGVGLSLQSFNrtPSGDCTR-------GIMAVLKALDSMTAAINSDSERPTGVCVYVEPWHADVRAVLNMRGMlAADESLRCDNIFSCLWTPDLFFQRYQRHLDgeravkWTLFD-DRASHLASLHGPD---FAREYERLERLGLGV-ESLPIQDMAFLIVRSAVMTGSPFLMMKDACNRHFHTDTRGAALATSNLCTEIVQRATP--------GENGVCNLASVNLPAClaggaFDFAALRRAARVAAVFVNAMMRIGNYPTGASVEGVRRSRSLGIGLQGLHTTVLALDMDMADPAARRLNAAIAEELLYGVMDASVELC-ERGlrPFDGFEHSRYARGVMPFDAYER-----VSLREPMRWDALRVRIAEHGVYNAQFVALMPTVSSSQVTESSEGFSPTFTNMFSKVTISGELLRPNlPLMETLRRLfprecarrdavarleraqwsvaaafgelpaghplakFKTAFE-YDQELLIDMCADRAPFVDHSQSMSLFLTEPA--DGKLHASRVMGLLMRAYNLGLKTgMYYCKIRKATNNGVFTGGDLV----CTSC----
>UniRef50_B4RFH2(48-548:570) Ribonucleoside-diphosphate reductase alpha chain n=1 Tax=Phenylobacterium zucineum HLK1 RepID=B4RFH2_PHEZH  E=1e-106 s/c=0.77 id=25% cov=54%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGGVGCDVSGAPPAGAAAERGP-PAPGPVGYLHLWDAACRVFLAGATRQGALMGALRCDHPDVEAFAAAKTAPGALSR----FNLSVAVTEAFMAAVAADADWPLRFPVET-------------------------GPVVRTVRARGLWTRILRCAYETGDPGVLFIDRINAENPLAW-RERLAATNPCGEVPLP------------DYGACDLGSLNLTRFVaapftpearlDLAGLAEAAAAAVRLLDDVIDISAFPLAAQADEARATRRIGLGITGLADALVMLGLRYGEAASLRAAGEAMRTIRDAAYGASAGLAREKGAFPACEAERLLAGPFARRLP----------------EPLRAAIARHGLRNSHLLAVAPAGSISLLAgGISPGLEPIFAAVQERtlRTSPGETRAVrwtaasvalwrraTGEAAGLPPAFAAAHDIPA-DAHLDMQAALQPYVDQAISKTVNV------PVETPFEDFARIYAGAHARGLK----------------------------------
>UniRef50_Q897Z5(13-795:1047) Ribonucleoside-diphosphate reductase (Vitamin B12-dependent) n=3 Tax=Clostridium RepID=Q897Z5_CLOTE  E=9e-98 s/c=0.46 id=23% cov=63%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTQASACFILSIEDKLlgsHSISDQYVNETKLFKGGSGTGTNFSTIRAKGEKLSG-GGVSSGLMSFLKGLDRNAGAIKSGGtTRRAAKMVCLDIDHPEILDFITWKAREEDkvralgkmgydmdidgeayETVSGQNSNNSIRFSDFFMEKVKNLDSM----PDDTIELEG-----------------RVDSSVNQKVKVKDLWDSFAKSTWMCADPAPQFSDTFNAWHtcpagedgNVNAKHNKINSTNPCGEYAF------------LDNSSCNLASINIYKFYdgkekniDLESYLHVVGLVQLALEASIYWGQFPTKDIAQKTYMFRATGLGITNLASLLMVLGYPYNSTEARNISSALVGLLTGYSYYISSLMAKEIGTFEKFSINKphmlkvirnhakvagsinglyedlnYNPVKVDHNLLENIGFSDLSNLLKKSWLKALNSGEEHGYRNAQVSVIAPTGTISFAMDCgATSIEPFFSHvVYKKLSGGGMMTVTNPVIElslknlgyskeqikdilqyvlekevvqtkegfkyekvldgkiegapHLKKEHYAIFDTANKcgsgkryiepMGHVKMVAALTPLISGAISKTVNL------PNNATIEDFKKVILNSWELGVKgiALY----RDGCKASQ-------------------
>UniRef50_C6BZ68(29-727:894) Ribonucleoside-diphosphate reductase n=1 Tax=Desulfovibrio salexigens DSM 2638 RepID=C6BZ68_DESAD  E=1e-95 s/c=0.51 id=22% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELLQSGRFIPAGSILSGLGNEHAKcsLSNCYLAKIEsDSLEGIFEAQKKLARTYSYRGGSGIDITILRPSGDPVNNAAVTSSGAVSFMPLFSELTNTIGQNG-RRGALMISIDIRHPETRRFIWCKSKPeeifGVDSltGKVQDVfgaNISLKVTDEFMQAVEEDKDWTFIFPDrfkisgkiinestlqllpEVYEALSPQVGDRIEaeitykvigidskkhqikvqpdlpinedstalseenltfilsrkrnetsdifdpvksvyntlWDGDYSRWQELGLPLRKydTVKARDLLEEISESAWKSGDPGILYQDTTQRNTPgtyIDPLRLKPMSTNPCGEQAL------------GYWSNCLLGAMVLYRYvvnpftkearFDSDLFHDDLTRTMAFMDTMSDLNQnkHPLQKHRDADKYGKRIGIEFTGLGDMLAMLGMRYGSEESIEFIKEIMRDKAITEISVSANIAERFGEVEALKTKDARQRFL-------DCPYISKLGLP---NKLQKKILKTGLRHTAFNTVGPSGSISIMSdNCTSGIEPVFMFSYARETrleagKVFEFIHMPPLKWMLetnqehlfgkytalqlkeKLNYVQADELDYMDR-IRMQAAIQQYTDSSISSTINLAE------ETPKETIFEIYLESWKHGLK----------------------------------
>UniRef50_UPI000155436D(4-562:563) hypothetical protein ORF029 n=1 Tax=Pseudomonas phage PA11 RepID=UPI000155436D  E=6e-95 s/c=0.63 id=24% cov=65%
--------------------------------------------------------------------------------------------------------------------------------------------------GWQLFKEKYLWEARGLKDTYE-------RIAKTAAQHTDDPDK--WAAKFFDVLWRGWLAASTPVLSNMGTIKGMPVSCSGQYIEDSIDGFYSAYHETAMLTKNGFGTSGYLGDIRPRGSII-STGGKASGTLPIFKHFVQDMRDVAQGTSRRGAWAGYLPIDHGDFYEIVDYLKNFPD------DLNIGWNLSQAFIDRLEVGD-----------------------------------------VDAVQRFQRAMYVKAITGKGYFFKPDTVNAMNPQvyKDRGLEVKASNLCTEITL--------FSDEDHTFTCVLSSMNLEKYDEWKN-TDAVFVSTVFLDCVAQefirlaKGQKGFEKSVRFTEASRALGLGALGFHTYLQAKMIPLESFEAHMINLEIFQHLHEEATRATKWMAKAWGEPEWCKG--------------------------------------YGVRNTHLLAIAPNTSSALICgGVSQGIEPVVANLYNQPTSAGEIYRVNPVFLNLakkrvgwtdelvkdliksegsvqhldwlspkeKAVFKTAYEV-DQAALVRLAAARQPYICQAQSINLFFD------ANESEAYIAQIHKEALLNpQIKSLYYMRTKAGVQASKG---------ECEACS---
>UniRef50_A4WLF4(1-442:1240) Ribonucleoside-diphosphate reductase n=2 Tax=Thermoproteaceae RepID=A4WLF4_PYRAR  E=7e-87 s/c=0.73 id=19% cov=52%
----MSVNKLDGRVEPFSMEKLKISIAKAGADVGVDTNVDVSLEVKKEV---VWSWELADMVQLELLKR-AIDRPELALVAQSHLLGRVYKEAFGKDFLKTKVGYgeraaarFKSLVDAGLLKREALEFLSKFEPR-------PEFDRSLSYNALRLFTNgNYALRDQ-NFRLAETPSMAAWRVATAVARE------LERARLYYDYITKLKIVPASPFWFNAWTKKEMFASCFTLEVEDCLSSithpgrycIYDALAYSGIIQQLGGGVGYDFSLLRPEGDVVRGSVGVASGPISFMRLFDTNVDVIKQGGKRRGAQMGTLHVWHPDIRKFIKAKTGELKD-AHLQNFNISVFADDTFMEKalgIDQNPKYKLINPRAFVEKTGT--KPVEYVDEREVAIPEEA--VWGEINAKELFKEIAHGAWDSGDPGMIFKSNLNASNP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4XRN9(1-267:1096) Ribonucleoside-diphosphate reductase n=2 Tax=Desulfovibrio RepID=C4XRN9_DESMR  E=2e-80 s/c=1.13 id=24% cov=34%
------------------------------------------------------------------------------------------------------------------------------------------------------LSKRYLKKSP-EGAPEEDVQGLFWRVAGAIASEEAKYAASPWqpealARKFYDLMVGMRFLPNSPTLMNAGTPLGQLAACFVLPVGDSMDEIFDAVKFAALIHKSGGGTGFSFSRLRPKKSRVGSTGGVASGPVSFMRIFNTATEQVKQGGTRRGANMGILRIDHPDILEFIACKEREGE----LTNFNISVALTERFMQAVEKGEDYDLIDPRDGSK--------------------------RGSLSAPEVFALLVRKAWESGDPGIVFLDRINRDNPT-PALGAIESTNPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9RBG7(657-952:955) Ribonucleoside-diphosphate reductase n=1 Tax=Ammonifex degensii KC4 RepID=C9RBG7_AMMDK  E=2e-70 s/c=0.91 id=28% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLGSINLLNMVDgagfsWEKLREVVHLAVRFLDDVIEVNNFPVPAIAAATRRTRKVGLGVMGWADALFKLGIPYDSEAALGLGAEVMRFIREEARAASRQLAEERGTFPAWEDSVY----------------YPHLP----------------LRNATLTTIAPTGSISAIAGVSPGIEPVFALAYTRMVLDGKKLLVVdkvfqeyveqnfppsrreeimagvsrtgnlglcaeelDLPEDMRRLFKTALEIAP-EWHLRHQATFQQYTDNAVSKTINL------PSDSSPEEVGQIFWKAFELKVKglTVY----RTGSRREQPLLLPT-------------
>UniRef50_D1GPW6(25-380:1091) Ribonucleoside-diphosphate reductase n=1 Tax=Staphylococcus aureus subsp. aureus TW20 RepID=D1GPW6_STAA0  E=2e-69 s/c=0.75 id=22% cov=43%
------------------------------------------------------------------------------------------------------------LVEEDYYID-VFKDYSEETLLELLDYAYSFGFEFQSFMAASKFYDTYALKTRDKSQWLEDFEQHNVIVSLYLAG-----GDVDLAKRYIKAHTLQTVQTATPTYLNAGRKHrGELASCYLFTMDDTLNSINFIRSQVSQASKIAGGVAVNLTRLRGRGATLKGVKNVGKGIVPVAKLIEGEVSYADQLGQRAGAGAAYLNIFHSDVIELLNTKKVNADEDTRLATLSIGLIVPSLFFDLAKEDKDLYMFEPYSIQEEFGKDVIlDDININDWYDKFVENENVIKHKINAREMLNLIAQIQLQSGYPYIMYKDNANKNHALNE-LGEIKMSNLC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1GPW6(757-1091:1091) Ribonucleoside-diphosphate reductase n=1 Tax=Staphylococcus aureus subsp. aureus TW20 RepID=D1GPW6_STAA0  E=6e-63 s/c=0.73 id=24% cov=40%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CTEIFQYMHVSDikdyNEQDELGQDIICNLASLNMVKSIEEKEIEESIRTGMRALTFVANNSRIEhLPTVHKANKNNRAVGLGVMSFHSMCAKNKIRYGSEESLDLLNVYCMMMDYYSLDESMKIAverndkfygfdqtdykakddKEFGEY-FYKNNRVTKNVEPITPKIKEIFKGIYIPTKEDWQRLAREVDKNGLYNSYRLSIAPyrTQSISYITNCSSALTPVVDVVEKRKYGNSETYYPMPYlsPETMWFYSPTAFDIP-QEHIINVAAVAQKWIDQGVSTILFVN------SEIETNKLARLYAYAHDRGLKSLYYTRNKLISIA------------ECTSCAV--
>UniRef50_Q122S1(21-300:1189) Ribonucleoside reductase n=3 Tax=Proteobacteria RepID=Q122S1_POLSJ   E=1e-68 s/c=0.94 id=21% cov=32%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDLYRRVARALASVEPEAARAEHEALFLENLHAGAIG-AGRIMSAAGTSiQATLINCFVQPVGDCIQgmddggypGIYEALREAAETMRRGGGVGYDFSRIRPRGAEVKATASMASGPCSYINVFDQSCSTVESAGARRGAQMGVLRIDHPDVFEFITAKRTPG----RWNNFNVSVGVSDAFMQALGDDQPWELVH----RAKPGARLIAQGAFQR------ADGLWVYQTLAASELWDTVMRSAYDFAEPGILFLDHINQDNN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8GMT3(701-1032:1137) Ribonucleoside-diphosphate reductase n=3 Tax=Thioalkalivibrio RepID=B8GMT3_THISH  E=2e-62 s/c=0.73 id=24% cov=35%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CLLGSVDLTRFvqhpftgklrFDWDTYREVVAVFTRMLDNVVEIHGLPLAQQAEALERTRRHGMGFLGLGSALAMMGIRYDSPEAAAFTERAARELALTGWRTGLELAREKGPaplmYERFTVTEHLLARYPalAEDGIRVGDVLPGRVLHARYSPYMRRIagldpalvaalAEEGARFTHHSAIAPTGTIALSFGNnvSNGIEPSFAHTYLRNIlgRDGATRDTVPVtayellawralvdpdadpeakqgPHRLPEAFVTAGDIAP-RAHLAIQAAAQPWIDAAISKTINV------PTDCPFEDFRDLYREAHALGLKgcTTYRLN----------------------------
>UniRef50_O55716(6-272:959) IIV-6 RIR1 intein n=1 Tax=Invertebrate iridescent virus 6 RepID=RIR1_IIV6  E=6e-57 s/c=0.84 id=25% cov=34%
--------------------------------------------------------------------------------------------------------------------------------------IDLSRDSKFDELGLKRLRESYMMREET------SPQERFAYVCKQV------GTDRDHSQRLYEYTSKHWLSLSTPILSFGKANHGLPISCYLSWIEDTKEGLIDTLSEVNQLSM--------LGGGVGVGVGIRTSDNKSTGVMSHLNTYDACSLAYKQDGVRRGSYAMYLNNNHPDVLQFIEMRKPTGDHNIRCLNLHHGLNISDEFMELIEKcdgggniDDTWNLIDPHTKK---------------------------ITTVGARDLWQRILETRMKTGEPYICFIDTCNKHmYDFQKKKGlTIKQSNLC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2S696(632-932:932) Ribonucleoside-diphosphate reductase, alpha chain n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S696_SALRD  E=9e-57 s/c=0.74 id=28% cov=35%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CSEIALPSGP--------DESFVCCLSSMNALHYDDWKD-TDAVETLTQFLDAVmqefIDgaKGMAHMDRAVRFAERHRAIGIGILGWHSYLQSNRIPFESAEASLTGAEIAKTIKERSYAASAELADRFGEPPVLEG--------------------------------------YGRRNATTMAVAPTKSSSFILGqVSPSIEPIKSNYFVQDrakmkvtyknphlqallqekgrdtdavwdeiaLRDGSVQHLDFLSDEEKDVFKTFSEIS-QMAIIDQAAGRQKHIDQSQSLNLAID-----PGSTPVKDINRLYVEAWKKGVKSLYY---QHGVNAAQSFSRDLLACKACEA-----
>UniRef50_Q91TP4(433-917:1035) T45 n=1 Tax=Tupaiid herpesvirus 1 RepID=Q91TP4_TUHV1   E=5e-54 s/c=0.44 id=22% cov=44%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARLCRSRQRRATFVRVYFDLWHTQAAAILELIERSASG---LDGVEFAVNVPNLFFERERhAKSHWTMFPYEHCAELNERT---GAEFATVYVQKERNR--CGWSVSLGWLYARLVR-AVLTGRLAVVFPDNVGVYGPLlgtmqnVPTLGPhVDMLNVCVERHVPVVRFNVNVDDcyeenvpDGRVSEMDLYIVSSGLAISLCHFRRLVRAAVVAGDLLLeEIFEQQGPQLGVAFQRYRPLCVGYSGLHTLLLRVGVEYDSDEAVTVAERLAEHLYYEALRTSVDLCIAGLPaCSWFGHTRYSRGLFAFERHGRRPCSVPERL----WDALREDMSAFGMRNAQLVSLGPGWEQARLAGVSASFYP----------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3QY00(112-456:1966) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Bacteria RepID=B3QY00_CHLT3  E=2e-46 s/c=0.55 id=22% cov=29%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRPQAHACFIQSVQDDLvneGGIFDLVVREARVFKFGSGTGTNFSNIRAEGEMLSG-GGTSSGLMSFLKIFDAAAGAIKSGGtTRRAAKMVIVNIDHPDIEEFIEWK---AKEEEKVAAMVAGSKINSTFLKAILHEALENGADRKTNPALNDLIQRalyrgvpmnyilrtlslvsqgftslDFESYDTHYEseaystvsgqnsnntirltnefmQAVENDEMwelrwrtdgsVCRTVRAAELWNKIAFSAWKCADPGLQFDTTINEWHTC-PNDGRINASNPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3B5C1(47-456:1521) Ribonucleotide reductase family protein n=9 Tax=Bacteria RepID=Q3B5C1_PELLD  E=1e-38 s/c=0.40 id=21% cov=29%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRPQAHACFIQSVNDDLvneGGIFDLAVREARVFKFGSGSGTNYSNLRSSGEKLSGGGSSSG-LMSFLKIFDSAAGAIKSGGtTRRAAKMVIIDIDHPDVEKFIEWK---AREEDKVASLVAGSRICSRFLQAIVEEAILNGADRLENPKLqrlienalhravpmsyiirvlalveQGYTTLDFEEYDTHYESEayqtvggqnsnntvrvtnafmkavennelwmlkERTTGKTARAVNARELWEKILLSAWKCADPGLQFDTTINEWHTC-PAAGRINASNPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P16782(237-799:906) Ribonucleoside-diphosphate reductase large subunit-like protein UL45 n=18 Tax=Cytomegalovirus RepID=RIR1_HCMVA  E=2e-43 s/c=0.32 id=25% cov=39%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YAFNVPSVLMKRYRAREQrYSLFGRPVSRRLSD--LGQESAFEKEYSRCEQ--SCPKVVVNTDDFLKKMLLCALK-GRASVVFVHHVVKYSIMADSVCLPPCLSPDMASCHFGECDMPVQRLTVNVARCvfarsdeqklHLPDVVLGntrRYFDLSVLRELVTEAVVwgnaRLDALMSASEWWVESA---LEKLRPLHIGVAGLHTALMRLGFTY--FASWDLIERIFEHMYFAAVRASVDLCKSGLPrCEWFERTIYQEGKFIFELYRLPRLSIAS----ARWEALRADMLEFGLRNCQFLAVGPDDEVAHLWGVTPSVWASRGTVFEEET------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI00016C6541(28-547:706) ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Clostridium difficile QCD-76w55 RepID=UPI00016C6541  E=1e-10 s/c=0.14 id=19% cov=25%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------INYSYVRDAGEPLKRFGGRASGhesLLVMFKKINNITLGIKKLST--------INC--LDIATIIS--ENVVCGGVRRSSLII-LCDPDD-IDLINAKKDIYSID------KNGNFLID----ESVGHRRMSNNSILFQSKPSINKIKEVMESIKNNGEPGFL-----NGENALKRKSD-FEGCNPCGEILLKSK------------SCCNLTTTNLVNFISNDKldidalksvLRLSVRIALRM---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1CID8(11-782:819) Ribonucleoside-diphosphate reductase n=7 Tax=Bacteria RepID=D1CID8_THET1  E=0 s/c=1.01 id=28% cov=95%
------VVSPEGGLVPLDPDRVRRHLQHACRGLPECDPDELANEVVRSLYDRVTPEQIRSAMILAARARIERD-PAYDKVASRLMLEQIYQESWGwvpseAELAATYREMFPRYVHACISAGRLSEELARFDLARLASALRPERDEKLRYIGLQTLYDRYLL--DVEGRRLEAPQYFWMRVAMGLALRE--DDPNARAAQFYDLLSSLRFVSATPTLFNSGTPHPQLSSCYLSTVEDDLEHIFKVIGDNAKLSKWAGGLGNDWTRVRATGALIRGTHGKSQGVIPFLKIVNDTAVAVNQGGKRKGAVCCYLEPWHLDFEEFLELRKNTGDERRRTHDMHTASWVPDLFMRRVQEGGTWTLFSPNEVPDLHELYGRAFERRYVEYERMAEEGKLRqHKRVDAKMLWRKMLSMLWETGHPWIAFKDPSNIRSA-QDHVGVIHSSNLCTEILLPTS--------REETAVCNLGSINLVEHlsgdgLDEAKLAETVRTAVRMLDNVIDINFYPTPEARRSNLRHRPIGLGIMGFHDALLALRIPYASPQAVEFSDQTMELISWHAIMASSELAAERGRYPSYQGSKWSRGLLPIDTielleRERGGDLEMDRTARLDWGPVREAVARWGVRNSQIMAIAPTATISNIAGVSQSIEPHYRNLFVKSNLSGDFTIVNPYlvedlkrlglwsqemldrikyydgsilpieeiPDEVKHLYLTAHEIDPL-WLIECASRRQKWVDMGQSLNIYVAEP-------SGKKLHEIYFAAWRKGLKTTYYLRAVGATNVEKASMDIN-------------
>UniRef50_C5DEU8(6-791:867) Ribonucleoside-diphosphate reductase n=2 Tax=Saccharomycetales RepID=C5DEU8_LACTC  E=0 s/c=0.94 id=28% cov=95%
-----VVSDRNGEANKLTSQALAQSLKQLAGGLqiEDADFDAVSRRILDAVPPSATHSSVVQFGGEVLAAM-STTHPDFANLAARWEISELHKKLQGlsftenlallqklrsSSKAPTVKRHKTSTSHNDKnLISAAFYEMALRYQTTLDAAIQPDRDFDFSYFGWKTLSKSYLIK-RKNEETHETPQFLFMRVALAIHG---PRGDIDAVLETYDLMSRKFFIHASPTLFNAGTVNQYLSSCFLVAmIEDSIDGIYRTLHKTAMISKASGGVGVHVSNVRGTGAYISGSNGTSNGLVPMLRVFNNTARYVDQGGnKRPGAFCIYLEPWHSDVLDFLQLRKNQGKEELRARDLFLALWIPDLFMERVEQNGSWCLFSPDEAPGLQECF---GEEFKKLYETYEKTLAPAKK-MPAQKLWSEILQSQVETGGPFMLYKDSCNNKSN-QKNLGTIKSSNLCCEIVQYSSPS--------ETAVCNLASVALPSFvklqreqaiFDFESLHKIVKVLTKNLDSVIDICDYPVEDAKFSNEKNRPIAIGVQGLADALMILRIPFHSESARVLNKQIFETIYHAAVETSIERSKKLGPYPSFDNSPVSRGEFQFDLWGLNDDNY--EFLFSDWKEMREKVKQHGIRNSLLVGPMPTASTSQILGFTESFEPMTSNIYTRRVLSGEFTVINKYmvddfcrlgiwneklknriieqngsiqgiegiPSNLKELYRTVWEI-PQRVMIDLSADRGPFIDQSQSLNLFLREP-------TMGKLTSMHFYGWKKGLKTgMYYLRTQAASGAIKFT----INQENTLRGAVSI
>UniRef50_P74240(31-766:767) Ribonucleoside-diphosphate reductase subunit alpha n=12 Tax=Cyanobacteria RepID=RIR1_SYNY3  E=0 s/c=0.92 id=30% cov=95%
------VIRRDGSSTPLNIGKIRAVVDWACLGLE-VNSIALEAGLTTRLREGISTREIQDNLISCALEMCSPNEPDWRYVAGRLHVWSLWKDTLvrRGYQYGQYLRTVQTKVTNGEYDSRILT-YSEGELQEAGCWINSDWDTDYDYAGAVLLTSRYLLPN-------ELPQEALLTCALLLASVEAPDRRLQWARRFYESIAARRISLATPILANLRVPGGSLTSCFIVAMEDNLESIFGEITNAARISKNGGGVGVNVSRIRATGSWVMGKPNASGGVIPWTKLLNDTAIAVNQGGRRAGAVTVGLDVWHLDVPEFLEMQAENGDQRRKAYDIFPQLILPDEFMRRVINKEDWTLVDPYEVREKMGIELAElwGEQFEGAYREIESNLDTTitlYKRINARELFKQIMRTQVETGMPYLSFKDTINKANP-NKHLGYIPGTNLCCESFSNVTPGQDA-------HCCNLVSLNLAN-LDLQDIAGVSQIAVRMLDNTIELTAPPFADAKSHNNKYRTIGVGAMGLADWLAKRRLNYDE---LADINRLFEEIGYWCTQSSMELAKERGAYPAFPGSDWQKGLLIGSKPVSWFQANAAKPER--WEKLSNDIQTHGIRNSHITAIAPNTSSSLVQGCTASILPVYSRFFYDKWAKGTVPIAPPFIGNCFWFYPENKTM-DQRKVVKAVAAIQQWTDTGISMELlfNLNAGIYFPEEpersLNAKDIFDTLVMAWEAGCKAIYYIRTvqKDDFKDS---------SDGCVACA---
>UniRef50_C9KMB2(34-754:755) Ribonucleoside-diphosphate reductase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KMB2_9FIRM  E=0 s/c=0.93 id=27% cov=88%
-----------------------------------------------------------QALVRAAVELASAEAPHWDKIAARLRYLVFARQLSEDEarrGITNFVAKLRYLTAKGLYGSYILEHYTERELSAAARFMAEERNHLYTYAGLDLLLSRYVIHTH-HGVALESPQEMYLGIALHLAMLELPAVRMDWVRRFYDMLSLQQVTMATPTLANARKPYHQLSSCFIDTVPDSLEGIYRSLDSFAKVSKWGGGMGLYFGKVRATGAAIRGFEGAAGGVIRWIRLVNDTAVAVDQLGVRQGACAVYLDAWHKDLPEFLQLRTNNGDDRMKAHDIFPAVCYPDLFWKLAKEdlDAPWFLMDPHEIEMVMGYALEDfwGEEWEKRYRACVAEPRIDKRVISVKEIVRLILKSVVETGTPFAFYRDTVNRLNP-NPQAGMIYCSNLCTEIAQNMSPVEAVSTEirtkdgdtvvqvttrPGDFVVCNLASLNLGRIDvtSHEELRTVVRTAVRALDNVIDLNEAPLAYAKLTNAKYRSIGLGVSGYHHMLAKNAIRWESEEHLAFVDDVFARINYAAIEASSDLAAEKGTYGCFAGSDWQTG-----AYFKKRGYMS-----EAWQKLAAKVRAQGMRNAYLLAVAPTSSTSILVGTTAGVDPIMKRFFLEEKKGAILPRIAPDLSMKTYWYYKSAHTVDQNWSVRAAGVRQRHIDQAQSVNLYIT------NDFTFRQVLALYIRAYEEGVKTIYYVRSKS------------LEVEECESCS---
>UniRef50_B4UA32(1-900:1005) Ribonucleoside-diphosphate reductase n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4UA32_HYDS0  E=0 s/c=0.74 id=29% cov=92%
----MEVIKRSGAREKLDLLKIRTVLenalsllkewkttkdisaqdieEWTMEDLNEINIDEIMEDIEINIFDGIETAAIFQHILHSLLTR-AIDDPIYDAMARNVLLQRIYKQAFGGmYSPKKAYkelfiDYIDNAVELGLLDEKLASYY---DLEMLALELVPKRDQLLKFNGLYNLMDRYLIKDLDTGNILEAPQWFWMRVAMGVALVEKtPEDRNHWAIEFYHMMSSMEFIPSTPTLFNSGTRFPQLSSCFVVDEEDDLSKIFETVKQVGMLNKHAGGVGLPATKLRAKDSIIRSIQGKSSGIIPFLKIIDETITAVSQGGRRRGSALASLEPWHLDVFDFVRTKRKWGDDSQRFKNLKIALFLNDEFMRRVEENGDWYLFDPADCPKLVSTY---GKKFSREYSKCIRKalsGKIRHKKIKAVELFKEAIENTIQTGEPWYTFKDPINIRHP-NKHTGTILTTNLCTEQLLVSTY--------DSIESCNLGSLVLPRAllthfrvnehaqplnssengskhtkflsnntFDWEKFKAVIRKAIRFLDNVIDANYYALEAVEKGTKQSRKIGLGFMGYQDMIEKLKLPVDSKEALKLLDKIGETMSYVAIETSVELAKERGTYPNFDGSDWSKGILPIDTlehlfrersltndkyttpyndmvqnyadenravqsrfddrehaqplnssengarhtidYKKLVDKYVGLQVYHDsddiaedesraisshfdakeqdksttvsqtlqssenglehtlpafnWEELREKVKQ-GIRNACQTTLAPTATISIIAGTSQSFEPYYALVYSRTNIAGRFLEVNenfirdlkklglwdrlredvllqqgsiqdikEIPQEIKDIYKTAYEIDT-EVYIKQAAVLQKWIDSSISRNLYFNTRDP-------QKIMEIYLKAWKYGLKATYY------------------------------
>UniRef50_A5TVY2(6-754:755) Ribonucleoside-diphosphate reductase n=15 Tax=Fusobacterium RepID=A5TVY2_FUSNP  E=0 s/c=0.87 id=30% cov=96%
------VINRDNIVEDLNIEKIREKLLRACEGLE-VNMVELESNIDSIYEENITTQKIQASLINTAVAMTTFEESDWSYVAGRLLMMEAEREVYhsRGFSYGDFSKTIRKMVELGLYDERLLS-YTEEELNQIAQLIDVNRDMVYDYAGANMFVNRYLIK--YDGKTYELPQETFMAISMMLALNEKAgETRVEIVKEFYNALSLRKLSLATPILANLRIPHGNLSSCFITAIDDNIESIFYNIDSIARISKNGGGVGVNVSRIRAKGSMVNGYYNASGGVVPWIRIINDTAVAVNQQGRRAGAVTVALDTWHLDIETFLELQTENGDQRGKAYDIYPQVVCSNLFMKRVKNNETWTLLDPYEIRKKYGIELCElyGYEFENLYEKIENDPNIKlKKVLSAKELFKSIMKTQLETGMPYIFFKDRANEVN-HNSHMGMIGNGNLCMESFSNFKPTINFVEEEegntsirrsemGEIHTCNLISINLAELTS-EELEKHVALAVRALDNTIDLTVTPLKESNKHNLLYRTIGVGAMGLADYLAREYMIY--EESINEINELFERIALYSIKASALLAKDRGAYKAFKGSKWDQGIFYG---KKREWYDTNSKFKDEWNEAFYLVETNGLRNGELTAIAPNTSTSLLMGSTASVTPTFSRFFIEKNQRGAIPRTVKHLKDRAWFYPEFKNVNPI-SYVKIMAKIGSWVTQGVSMEMVFDLNK----DIKAKDIYDTLITAWEEGCKSVYYIRT------IQKNTNNISDKEECESCS---
>UniRef50_UPI000194E523(45-811:847) PREDICTED: ribonucleoside-diphosphate reductase M1 chain n=1 Tax=Taeniopygia guttata RepID=UPI000194E523  E=1e-177 s/c=0.81 id=26% cov=88%
----------DGRQERVMFDKITSRIQKLCYGLNADFVDPLCVSS----FPGAQFLLWDLDLLVPEASQASSNPP----------------KTCDVMEDLYTYINPHNGKHSPMISKETLD-IVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLK--INSKVAERPQHMLMRVSVGIHKA-----DIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLCMkDDSIEGIYDTLKQCALISKSAGGIGLAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGnKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDDVW---GEEFEKLYESYERQGR-VRRVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSN-QQNLGTIKCSNLCTEIVEYTS--------REEVAVCNLASIALNMYvtpehsYDFKKLAEVTKVIVRNLNKIIDINYYPVPEdlnraqfvrgaphAELSSEETwlpqtpRSpealpgfWGSGLTGL-----RVRCSYERQGRVRRVVK-AQQLWYAIIESQTETGT---PYMLYKDSCnrksnqqnlgtikcsnlcteiveytSREEILQYDMWNVTPSDL------WDWKALKEKIAKYGVRNSLLISPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQVVNPhllkdlterglwneemknqiiahngsiqnipeIPDDLKQLYKTVWEIS-QKTILKMAADRGAFIDQSQSLNIHIAEPNYG-------KLTSMHFYGWKQGLKTgMYYLRTKPAANPIQFTL----------------
>UniRef50_A0B8R8(16-686:688) Ribonucleoside-diphosphate reductase n=2 Tax=Methanomicrobia RepID=A0B8R8_METTP  E=1e-175 s/c=0.92 id=22% cov=79%
------IRKRDGRIVDFDPSRISRAISKAFNALGIVDEKtpvelagRVVDVVDERFRDEIPSVEDVQDIVEE------------------VLIDAGYAQVAKAY---------------------ILYRQRRSEIREAKHYLGVADDLKLSVNAIEVLKKRYLKRDEF-GNVVETPGEMFERVASAVSAVERRYegDADDARKKFLSMMRSLSFLPNSPTLMNAGLPLGQLSACFVVPVEDSIAGIFDALKYMALIHQSGGGTGFSFSRLRPKGDVVRSTGGIASGPVSFMRIFDAATDVIKQGGRRRGANMGILRVDHPDITEFIACKDRGGMD-----NFNISVAITEEFMRQCERDGSVELINPRTGEA--------------------------TGEMSARDLMVMMATYAWRRGDPGVVFIDRINALHPVP---GIIEATNPCGEQPLLP------------FESCNLGSVNLSRMVErgeisWDRLEETVRLAVRFLDDVIDANRFPLKQIEDATLRTRKIGLGVMGFAEMLIQLGVSYASQDALRIAEELMAFITKTAREESCALGRERGSFPLFEESSLKK-----------------------WDA---------MRNATVTTIAPTGTISIIAGTSSGIEPLFAVSFVRHVLEgarliessplfermasergimtpalraevarrGSIQEIPGIPDDIKELFLTALDISP-EQHVRIQAAFQKHTDNAVSKTVNL------PEKASVSDVIKVYRLAYELGCKgiTVY-------------------------------
>UniRef50_A3MX47(4-806:853) Ribonucleoside-diphosphate reductase n=3 Tax=Pyrobaculum RepID=A3MX47_PYRCJ  E=1e-160 s/c=0.71 id=22% cov=91%
------VLKLNGSVEPFQPEKLRRSIERAAQDAGV----EVDGAADIKVERDVGSWELAD-LVHVELLKKAIERPELAEVAKSHLLGRIYKEIFGRDFLRVKSD--EEYQRRALAAFEKLAGVIKPEALELLRQLKlrPEFDRSLSYNALRLFTNgNYALR-RLDFQLAETPSM------AAARVATAVARDVERARLYYDYITSLKLIPASPYWFNAWTSKEMFASCFILMIEDCLSSithpgkrcIYDVLTRSGLIQQAGGGVGYDFSLLRPEGDVVRGSAGVASGPISFMKLFDANVEVIKQGGKRRGAQMGTLHVWHPDIRKFIKAKTGELKD-VHLQNFNISVVVDDAFMEKaldVDKDPNYPLVNPRIVVEKLGIKPIEVLELTRE-VQLPKDATV--GSVNAKELFREIVEGAWDSGDPGLIFKSNMNASNsllyvNVDGDRYVWFGTNPCAEVP------------GADKDVCNLTHINLVKFVkegcsgrtleekleciDWAGLAETARVGVRFLDDAVDISTTGMKDVDETYRKIRKIGLGVMGLAEMLIKLEIPYASWDAVTLVNRVLAWIYLNALDESAELARERGPFKYFHQSDYARGVIPVLKYQdfvwsrwervraayppeyrelgdrlkaityetrRWLDAMAKRFGKPTLAELSEKV-KGGVRNSVVMSVAPTGRTSILAGTTSGVEPVFALAFLRNVTVGTLVEYywpgveylrarglwtpevrraveesgmlrdAPVPEDVKHLLATAMEIHWA-WHVLMQASAQQWVDQGISKTINM------PANATKDDVYWAFALAWALGVKgiTVY----RDKSKSVQ-------------------
>UniRef50_C3XAC6(27-589:963) Ribonucleoside-diphosphate reductase n=3 Tax=Betaproteobacteria RepID=C3XAC6_OXAFO  E=1e-157 s/c=0.99 id=24% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVAQALAEVEAPKNKKKYAEEFLWALQNG-FIPAGRVSSAAGTGLQtTLINCFVQPVGDSITnmvdgkpGIYTALAQAAETMRRGGGVGYNFSSIRPRGAKVRGTGSSASGPISYMKVFDRSCETVESAGARRGAQMAVLNIDHPDIVEFITIKQ----EQNQLSNFNVSVGVTDKFMQAVESDGDFELAHVAEPNN----------ELKEKGSYKRADGKWVYSKVKARDIWDLVMKSTYNAAEPGVLYIDRINRENNLA-YCEVIEATNPCGEQPLP------------DYGCCCLGSLNLTSFvtapfsahplFDFNLFARVTKIAVRMLDNVLTATKWPLEEQAKEAAAKRRIGLGFTGLGDALIMLGIRYDSEEARILSSEISKAMRDAAYSGSIDLAKERGAFPMLDVENYLKGGFVSRL----------------PEEMKAQIRKHGIRNSHLTSIAPTGTISLAFadNASNGIEPAFSWFYNRvkRMPDGSkknytvedhayriYRSMGNDVSKLPDYFVSALEISAIDHML-MVAAVAPYIDAAISKTVNVAE------EYPYEDFKNLYMEAWKKGLKgiTTY-------------------------------
>UniRef50_C6IVG4(86-644:864) Ribonucleoside-diphosphate reductase n=2 Tax=Bacillales RepID=C6IVG4_9BACL  E=1e-152 s/c=0.97 id=23% cov=70%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------TPEEMWDRLAKAMASVEEtPEKQKEWEEKFRYILDDWKLVPGGRIAAGAGASDElTLFNCYVIPSPkDSRGGIMETLSEMTEIMARGGGVGINLSSLRPRRAIVRGVNGSSSGAVSWGGLFSYTTGLIEQGGSRRGALMLMINDWHPDVLDFITVKQTMG----QVTNANLSVCVSNAFMKAVKEDLDWDLVFPDTTyEDYNEVWDGDLDKWKADGRKV-----IHYRTVKAREIWHTIIESAWKSAEPGVVFMEYYNQMSN-SWYFNPIICTNPCGEQGLPGW------------GVCNLSAMNLSKFYDeekhdvaWDELATTTRYSVRFLDNVINKTPYHFEENEKNQKKERRVGLGTMGLAELMIKLNIRYGSPESLEFLDKLYGFIAKEAYLASADIAEEKGSFPAFEADKFLQSGFMKNMTEVYP-------------EVGEAVRTKGIRNVTIITQAPTGSTGTMVGTSTGIEPYFAFKYYRQSRLGFDEQFVPIAQEwmdahpgepLPDYFVTAMDLSAED-HIRVQAAIQRWVDSSISKTANC------PSDFTVEDTKRLYELAFDLGCKgvTIY----RDGSRDVQ-------------------
>UniRef50_C6D5S5(82-644:864) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Paenibacillus RepID=C6D5S5_PAESJ  E=1e-152 s/c=0.96 id=22% cov=70%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------TPEEMWNRLAGAMAGVEQgEEKRRTWTERFRYILDDWKLVPGGRIAAGAGASDElTLFNCYVIPSPkDSRGGIMTTLSEMTEIMARGGGVGINLSSLRPRRAVVAGVNGSSSGAVSWGGLFSYTTGLIEQGGSRRGALMLMINDWHPDVLDFITVKQTMG----QVTNANLSVCVSNAFMKAVKEDLDWELVFPDTKEtDYDELWDGDLEAWKKLGKKVV-----HYKTVRARDVWHTIIESAWKSAEPGVVFMEYYNQMSN-SWYFNPIICTNPCGEQGLPGW------------GVCNLSAINLSKFYDeskhdvnWEELGKVTQWSVRFLDNVIDTTPYHFEENEKNQKKERRVGLGTMGLAELMIKLGVRYGSPESLLFLDKIYGFMAREAYLASAEIASEKGSFEAFDAEKFLQSGFMKNMVSEFP-------------EVGEAVLAKGMRNVTVITQAPTGSTGTMVGTSTGIEPYFAFEYFRQSRLGFDKQLVPIAqawkdahpgEELPDYFVTAMNLSAKD-HIRVQAAIQRWVDSSISKTANC------PSDFTVEETKELYEMAFDLGCKgvTIY----RDGSRDVQ-------------------
>UniRef50_Q2T3W9(53-647:881) Ribonucleotide reductase system n=37 Tax=Burkholderiales RepID=Q2T3W9_BURTA  E=1e-151 s/c=0.90 id=23% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YRRVARGVAQAEPPELRDEIEARFVEHLQRGALG-AGRIMSAAGSSiAATLINCFVQPVGDCIQgvderglpGIYVALLQAAETMRRGGGVGYNFSAIRPRGAYVHSTGSSASGPCSYIDVFDASCRTVESAGARRGAQMAVLDCDHPDLLEFIEAKHSKG----RWNNFNISVAVTDAFMNAVEQDLPWQLVHRAEPSPALRAAGD---------LHRRDDGMWVYAERRARAIWDKIMRSTYDVAEPGVVFISKMNDDNNLR-AIESIRATNPCGEQPLPAY------------GCCNLGPLNLTRFvidpfarldggesvFDWDALAERTRTQVRFLDDVLDVTLWPLPEQRHEAQQKRRIGIGFTGLGDTLVMLGLRYDAQEGRDFAARVAREMRDAAYRASVELACERGAFPLFDASRYLE---------------EGTFASRLPDDIREAIRRDGIRNSHLLSIAPTGTVSLAFadNASNGIEPAFSWTYQRTkiMADGSrqtfavedyayrlYRELGGDVDALPGYFVSALQMSAHD-HLAMMAAVQPYIDTSISKTVNV------PADYPFDDFESLYFDAWKSGLK----------------------------------
>UniRef50_A7HK53(4-642:841) Ribonucleoside-diphosphate reductase n=11 Tax=Thermotogaceae RepID=A7HK53_FERNB  E=1e-144 s/c=0.81 id=22% cov=72%
---------------------------------------------------------------------------------------------------------------------------------TLTSVIEHWKDVELSKNAYKILSERYFLKTPSGEFLEKSWDDICRRVARVIATAELVNNPELkekspfeqldevkfWESTFFDFLKSRIFIPNSPTLFNAGmgvrhellwksiddmtledyweiynsrNHLHMLSACFVVPVEDSIEGIFEAVKEYALITKAGGGIGSNFSRLRPKGSFVAGTHGQASGPVSFMHVFNSAVGVVEQGYRRRGALMGILNIDHPDIEEFITAKEGN-DGEKVLKFFNISVGIT---MDR---------------QELLKLYMEDG-EIELKHPKCNGS-----KRVKVRELINKIAKNAWKTGDPGLAFLSEMNKYYAMYPEM-TIESTNPCGEIGLAPYE------------ACNLGSIDVAKFymngeFYWEAFAQATRLAVRFLDDVIDVNVFPLEKIRKAVTDSRRIGLGIMGFADLLYMMDIPYNSHEGRQFAADMTAYMAIHGHDESNKLAQLKGSFPLFEKSRY---------YREDEFAPFAMGMSKYDNELKEVFKesKKGKRNVAVLTIAPTGSISNIADTSSGLEPNFLLAYVRymnkhdgtkealfyvnkvlesklnkeileRVKDklverGSLQDIPEIPEEIKRVFVTAMDISPMDHLL-MQDAFQRYVDNNISKTINM------PNSATEEDVLNIYLEAMKLnirGL-TIY-------------------------------
>UniRef50_B1HSG6(50-695:697) Ribonucleoside-diphosphate reductase n=2 Tax=Bacillaceae RepID=B1HSG6_LYSSC  E=1e-144 s/c=0.80 id=22% cov=81%
-------------------------------------------------------------------------------------------------------EKIRYLVDEGYYEKAFIDMYEMDFIKKLYKKAYDYNFRFPSFMSASKFYDSYAMKSRDGEEILEKYEDRIVIIALYLAQ-----GNTVLAERSVEAMME-AYQPATPTALNSGKKaRGELVSCFKLSMDDSMNSIAENIGYCLELSRLGGGVGVNLTDLRPLGDPIKEILNRASGVIPVAKLLENSFSYSNQLGQRNGSGVVYLNIFHADIENFISSKKPNADDKIRLATLSTGIIIPSIFFELMKRDKDIVLFSPYDIFKVYGKRMSEIS-ISEMYYELLDNPKIRKiKRLNARRLYTEVKKAQFESGYPFEIFDDNVNDVHPL-KNIGRVKMSNLCTEILQVQETSVITDQDQpneyGLDVSCNLGSIDIHAASKVNDFEALIDTAMHLLTNVSQMTHIKnVPSVAKANQLMHSVGLGCMNLHGHLVTEGIMYGSKDSIHFMDRFMEAMNYYSLKSSMEMAKEKAeTFYRFEDSDYASGIYFDQYVNKTEEELSPAVLKALgnipiitskmWGLLKQDVMQYGLFHSYRLAIAPTGSISYIRSCTASISPCTERVEVRDYADSRTIYPMPHLtNENSHLYVEAYDVDPYD-LIDLYAASQKHVDQGISMTLYVTD------NWTTEQLAKVYIYAWVKGIKSVYYVRQR--------------------------
>UniRef50_Q3SMN2(32-589:600) Ribonucleoside-diphosphate reductase n=1 Tax=Thiobacillus denitrificans ATCC 25259 RepID=Q3SMN2_THIDA  E=1e-137 s/c=0.88 id=24% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------WQRVAQAVAQAE-VDARALWADRFYALLDDFRFLPGGRILAGAGSGHRvTLFNCFVMgEIADDIEDIFEALKEGALTMQHGGGVGYDFSTLRPAGTIAQATGTIASGPVSFMHIWDAMCATVLSTGARRGAMMATLRCDHPDIEAFVDAKRDPAV----LRHFNLSVQVSDAFIAAVDADADWPLVFP-----LRDGEPADGAVVRRHWTgSTTAVPCRVLRTVRARALWQRILRAAYDTAEPGVLFVDTINRDNTLAGR-ETLTTTNPCGEIPLPAY------------GACDLGSLNLTAFVvapfaadarlDLAALGDAAALAVRFLDDVIDVSRYPLQAQAREARFKRRIGLGITGLADALVLLGLDYDSEPARQLAERAMRTVRDAAYRASIDLAREKGGFPALERSAFLASGFAGRLPP----------------EIRDGIARDGIRNSHLLAIAPAGTISLLANNlSSGIEPIFAAEASRRILqpDGSYRsHAVSDYACLlwrahggvgqPPALVEAQQLDPV-AHLAMQAALQPAVDNAISKTINVA------ADIAFARFEALYRQAHALGLK----------------------------------
>UniRef50_B9KZV2(22-576:589) Ribonucleoside-diphosphate reductase n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9KZV2_THERP  E=1e-136 s/c=0.88 id=24% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------------------------------GRIIETEEELFWRVARAVAAAEDAFPRgprsAEIAEKFYELMTTLRFLPNTPALINAGTQLGQLFACFVIPVPDSLDGIFGAVRDAAKIQQTGGGTGFSFSHLRPRGDLVRSTRRPSSGAVSFIRIFDVASDVIATESVRGGANMAVLRCDHPDVREFIDAKRNPALFSR----FNFSVLVTDDFLRAAIERREIALINPRTG--------------------------LPFAQANAGELFDAMVDAAWEVGDPGLLFYDRIQRDNAV-PALGPLEATNPCGEVPLHPWE------------ACVLGSLNLRAFIvergdraflDEAGLQESARLALRFLDNMVEVSRYPKVEIETICRANRKVGLGIMGFADLLLALRIPYGSDESVAVADRVMGLVQAAAVEASRRLAEERGPFPNFPISRYAARGEPPR------------------------------RNATVTTVAPTGSISIIAGCSSGIEPLYALAYrhvgefvgivephpllLRELsrigkydpallheieVTGRIGHRTDLPEELRRLFRVATEISPEE-HIRVQAAVQRHVENAVSKTINL------PYEATRDDVRRAFLLAHELGCKgvTVY-------------------------------
>UniRef50_A4IY36(11-588:590) Ribonucleoside-diphosphate reductase n=26 Tax=root RepID=A4IY36_FRATW  E=1e-125 s/c=0.78 id=25% cov=67%
--------------------------------------------------------------------------------------------------------------------------------------IDLSRDRELSEQAQQLLTNYYCLQNEP------SPQYAFARAAVA-----YSFGDMNLAQRIYAAAAKGWFMFASPVLSNAPLPGVKvkslPISCFLSYVPDSLEGLIEHSSELRWLSVKGGGVGGHWSSVRA-------VSDKAPGPIPFMHTVDADMVAYRQGKTRKGSYAAYMDISHPDIIEFLGIRVPTGDVNRKCLNLHHAVNLTDDFMQAVANDQDWKLIDPDD--------------------------KTVRDVIKARKIWETILETRYRTGEPYLNFIDTANRALPkSQKDLGlTIKGSNLCNEIHL--------VTDEKRTAVCCLSSVNLERYDEWKD-TSLIKDLIRFLDNVlqffIDHAGDEISKARYSASRERSLGLGAMGFHSYLQLHRVPFESQRAKEINEEIFKRIKEQALEETLILGAEKGEAP--------------------------------------DMAGTGRRNAHLLAIAPNANSSLILNTSPSIEPWKANAFTSRTRVGSHLNKNKYLEqelekigknteevwsdiitnggsvqqldflskELKEVFKTAIEM-DQDWLVYLGGERQKYLCQGQSLNVFF------PAGASRGYLHKVHFNAWKYGCKGLYYLRTETSNRAE--------------------
>UniRef50_D0LZM4(89-722:963) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Bacteria RepID=D0LZM4_HALO1  E=1e-123 s/c=0.71 id=19% cov=65%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DELVHLLVNQKMAFNSPVWFNVGVETePQCSACFINSVDDSMSSILTLARTEGMLFKYGSGTGSNLSSLRSSAENLHG-GGTASGPVSFMRGFDAFAGAIKSGGKtRRAAKMVILDAEHPDIVDFVECKAKEeqkawalidagydggfnepggAYDSVNYQNANHSVRVSDSFMQAVVDDSSWTTHAVLDGRDIH--------------------------TMPARELMRKIADAAHLCGDPGMQFDSTINDWNPCIG-TARINASNPCSEYMF------------LDDSACNLASLNLRRFqsedgnFDVEAYKHAIEITTLAMEIIVDNASYPTPKIGENSHRFRPLGLGYANLGALLMSRGLPYDSEPGRAYAAALTAILCGQAYRTSARIAADaTGPFAGYDENREPflrvmnkHRKAVADIDAALVPYDLMEAARGAWNDVVELGEKHGFRNAQTTVLAPTGTIAFLMDCdTTGVEPDIALVKYKRLVGGGMLKMVNqtVPEALRRLGYSEQqlegiinHIDTQEsiegtsvlkeehlpvfdcafrspsgtrsihymGHIRMMSAVQPFLSGAISKTVNL------PSDCTVGDIEDAYLQAWKLGLKAI--------------------------------
>UniRef50_B6YRR4(2-638:867) Ribonucleoside-diphosphate reductase n=21 Tax=root RepID=B6YRR4_AZOPC  E=1e-120 s/c=0.68 id=24% cov=69%
--------------------------------------------------------------------------------------------------------------------------------------------------AAKVFVDKYALKSNKGEYFESTPNEMHQRIAREIVRIEQKYPNpILTEKNILEVISDFNYlIPQGGNMFGIGNSYQltSLSNCFVIGNrTDSYGGIMRTDEEQIQLMKRRGGVGHDLSHIRPRGSPVNNSAITSTGMVPFMERYSNSTREVAQEG-RRGALMLSMSVEHPEIESFIDAK----IEEGKVTGANISVKLTDEFMRAVESNRSFIQRFPIDS----------------------ENPQIIK-EIDAKDLWNKIIHNAWQSAEPGVLFWDTILRESIPDCYIdsgfGTV-STNPCGEIPLCPYDS------------CRLLAINLYSYvkqpfkkeaeFDFDLFEEHVALAQRMMDNIVDlevekidailmkiISDYESDEIKHTEQLLwekirhktligRRIGIGITAEGDMLAALGFRYGTEEATNFAERIQKVLALSVYRASVEVAKERGAFEIFN-------------IELEKNNPFIHRLKEVDSQLIEDMQQFGRRNIACLTIAPTGTTSLMSQTTSGIEPVFLPVYKRRRKVNPSDEItkIDFVDEMGDSWVeyTVFHHKFVKWMevqgypttrkyaqreidalvakspyykstsndvdwlqkVKMQGRIQRWVDHSISVTINL------PNETKEELVNYLYIEAWKSGCKgcTVY-------------------------------
>UniRef50_Q1J1T0(11-781:1010) Ribonucleoside-diphosphate reductase n=3 Tax=Deinococci RepID=Q1J1T0_DEIGD  E=1e-118 s/c=0.56 id=22% cov=68%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFRRIADWVAAAEAPEARERWAQKYYDLMAQKRFCPGGRVLAGAGTQHGNVLNCFVQGatehapesfdgimevakklalvtkvgggngvnldvytpraqgsrpdagvrgwvymsaahpdvgdfieglmrpptqpdgdkqpvavrnwtrvvygealpadlvararqngvqivralpggvqaVPDDMGGIIDAARAVAESAKVGVEPRIDLSQMRPEGAPIKGSGGTSSGPVSFlMEIFDNflewanrggetsgpintlryvyapVLRVVRQGGTRRGAGMATIAIEHPDVLDFLTAKDlDREAAEGDISTFNISILVSEQFWQALEGDALWH-VDVQEVPGKYYLAPqsgpydghlptlperaEDGARGVPLYRGAPRGrsqPADARPGVPAKWLWDQIAEHAWATGEPGLIFVDRVNEHSALKnlGKRYEIRSTNPCGEIPLTVGEP------------CDLGAINLAAYvqnsrFDFAAFRADVRTCVRFLDDVLDVNVFALEDNRVASQDLRRLGLGVMGLADALIKLGLRYDSEAGRAAIAEIMTALREEAVAESERLGQERGVYPVYERN-------------------------------AQKIPHSPRRNVAVLTVAPTGTTSMLMGVSSGIEPVFSPFIWRKIGAeyrallhplfmellnqyppaanmddgqggwnwdrvteavsenhGSVVGLAFIPEALQQVFVCAHDIKPLD-HVRMQGVVQQAFDaggqhaaNSLSKTINL------PNSATVADVRAAYAEAYRTGCKgiTVY----RDGSRQFQ-------------------
>UniRef50_B4D0S2(18-784:1043) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Verrucomicrobia RepID=B4D0S2_9BACT  E=1e-115 s/c=0.55 id=20% cov=64%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPQGSACFIQSVDDNMEDIMRLAMSEAMLFKYGSGTGSDLSTLRSTREKLSG-GGRPSGPLSFLKVYDQVANVVKSGGKtRRAAKMNTLKDWHPDIEEFIEAKTKeekkawalieqgydgsyNGDAYGSImyQNENLSVRVSDEFMNAAVEGKEW-------------------------WTKRVTDGKPCEKK-EAKALLRKIAEGTHLCGDPGVQFDTTIDKWHTCKG-TGRQNSTNPCSEYLF------------LDNTACNLASLNLLKFkkadggFDVERFKAAVRVFITAQEIIVDNASYPIKEIAENSHIFRTLGLGYANLGALIMSYGLGYDTDEGRALAGAITSIMTGHAYEQSAKLAKTMGPFPGYKDTRASGVKKTVDSTNEsymlevidlhrshvsriqdsDRFGYLKEEAQKCWDGALAQGKKHGYRNAQVTVLAPTGTIGFLMDCdTTGIEPDIALVKYKLLAGGGMLKIVnqtvkPALQNLGysfaeiegvvahiDKFDTIEDVTDEDgttipsglkpehlpvfdcafkphrgsrslhyrGHIRMMAAAQPFLSGAISKTVNL------PEEATVEDIVNTYVEGWQLGLKaiAIY----RDGSKRSAPLNVKKTKDMGTA------
>UniRef50_B0C346(20-649:649) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Acaryochloris marina MBIC11017 RepID=B0C346_ACAM1  E=1e-115 s/c=0.66 id=21% cov=69%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WQEKFLSILQPMKFVPGGSILANCDHGTRGLLNCFVLSAEDHIHDITKLVSDSVLTTKFRGGVGINIgaegskGYIRQKGAPFQ--DGKALGPCAVLDMVSENSKKITTGNKaRRGAFLFSMNWKHPDIWEFIQAKTQSTI------DANFAKSVMEELAQLAQQDEPsqgkqEKLKALHTEVGtaWVETHLNPEGKRDRRWHNAnisvqlddEFFAKLDQGDEEANKLWQAMAENAHATADPGLLLIDNAKRRSPIRDF---VTCTNPCGEIFLPP------------NSACNLGSLVLTKFVrrtaegnieiDWDDLAETVRIAIRFLDNVLDVSEFATPDQKHNVRDvFRQLGLGIMGWADYLKLARIPYDSARHLEEIDRWGSWIAAHAYRTSEAIAAEKGACGVWDQIKDIQTGNPFERWMDSEGNYYNGTEAHHND--RQDLTQVPRRNSTVLSIAPTGSIAQLAACSWAFEPDFGLTLWKqvfvdasRSQQNWVQILNPYLDELNlpeadaeivkqtgsladtnygkqhpeiaRSFKIAREIPPG-WHILVQSKWQSWIDSSISKTINL------PAHATVDEIKQIYRLAEKAGLKgvTIY----RSGTLDSEPIKVGNSEKD---------
>UniRef50_C9LXZ2(7-581:749) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Veillonellaceae RepID=C9LXZ2_9FIRM  E=1e-112 s/c=0.71 id=23% cov=59%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSNCYIMPSPtDDIESIFTVNQQIAKIFSYGGGIGVNISGLRPKDSRVNNVARSSTGAVSFLKIFNTTGEVISQNG-RRGAMLVALDSEHPDIYEFLHMKQ----ENEKLASMNLSILFSDAFMQAVIDDAEYELTF-----------------------DVEATGEKIRRTIRAAEFFDEYCQTQWDWGDPGALFKDRLNDYTLLSGYDEyKIEVTNPCGEFGGNAYNS------------CNLMSLNLYSFIEdkfgdaphiaEEEFRAAIQTAVRALDEVLDYGFDtqPLEENRQCIRDWRSVGLGLFGVADAFVAMKLAYGSRESCDFIQGVLRTMFTEAARTSAALAKEKGAFGKYD-------------WEKTKKSPLIQRLAEEAPEVYAEIKEYGLRNGTLLSIAPTGTISLLMGVfSGGCEPLYQISYERTThkmeeGSGSFRVYAHSVSDLLDYHKLPHDLTNEDikkrfpwvieshdvpylHRVELQAAMQKYVDNSISSTVNLK------HAATPADIRNIYLAAWKSRCK----------------------------------
>UniRef50_C1TR30(3-839:994) Ribonucleoside-diphosphate reductase n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TR30_9BACT  E=1e-105 s/c=0.46 id=23% cov=64%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TESQQLFACFVISVEDSIEGIFDSVKDAAVISKYGGGVGGNFGNLREFGSDIKgGTGGKASGPVSFMETWNTMGSVVVQGGRRRAALMGMLYDDHPDVERFMDAK----VEDGKLPYFNISVSVSDELLTKAAQGGDFHLRSRADGS--------------------------VAKTVKAADLWNKLCRNAWRRGDPGVFFGDRANVDNILKKAPQwRIESTNPCVTgdtwvmtdegpkqaVDLVGRPTTLLVDGKGhetegffstgvkpvfelktkeghslkltadhkvmvdvdgewswipagelsegsilrlhdhsgeekiskamfdslvpcgeeavfdvqvpgvnafdanglyvhncgeqplpNYTSCNLGSVNLEAFvssessgeavFDMDSFVDQVFRSVYYLDLVIDATSYPLERIADRTKMIRPVGLGLMGLADAAIMLGISYGSESFNRFCRSLGGTMASAALAATVRIVSEEGkdPFPEHRlvselmESFRCEAGLPdaVDRWLERMDEggfrellermrrtdtvpytlvntleallSAASVHKGDGMGLVREVLEalfsGRMRNSRRLSVAPTGSISMLLDASPGIEPNFAWSWSRKVMSStgdGGYETREYFHRLMtaehkdefrrtggisdPRFVTAYDIGT-DSHVEVTGIFAAVVDSGISKTVNL------PSEATVDDVRRVYEDCYRMGCKgiTIY----RDGSRSDQ-------------------
>UniRef50_A4WLF4(823-1193:1240) Ribonucleoside-diphosphate reductase n=2 Tax=Thermoproteaceae RepID=A4WLF4_PYRAR  E=8e-69 s/c=0.71 id=26% cov=36%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VCNLTHINLVKFVkdncgggsfeeklgciDWDGLAQAARVGTRFLDDAIDRSKTGIEVIDEMNAATRKNGLGIMGFAELLIKLGVPYASWEAVELINRIMGWIYVNALDESAELAREKGPFKFFHKSIYARGEIPvlkfqdhvWSRWERIKRVYPRELQEAgdklrditmrtrQWlgpylDKLSEKV-RGGVRNSVVLSIAPTGRTSILAGTTSGVEPVFALAFLRNVTVGTLVEYyepgiellksrglwtpqvrkvveetgmlrdAPVPEDVKHLLATAMEIGWL-WHVLMQASAQQWVDQGISKTINM------PANAPEEDVYWAFAFAWAVGVKgiTVY----RDKSKSVQ-------------------
>UniRef50_Q18GD3(567-1036:1909) Ribonucleoside-diphosphate reductase n=1 Tax=Haloquadratum walsbyi DSM 16790 RepID=Q18GD3_HALWD  E=9e-82 s/c=0.65 id=22% cov=41%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGGMGYAFWKLRPYGDSVGSTGGIASGPITFMRTYDQMCETIAQGGARRGAQMGVMRISHPDVIQFIHAKnkdvslahslrlndpddfthtsfadaleeaRELIDEEGRvpehlrnaveghLSNFNISVGVTDEFMEALFADEEFTFTNPRtEDPHIATPETKELYELHDLGEHVEVGEEL---SVPAEELWDHIVSGAHENGEPGVIYLERVNKEHSFdveKHSEHEILATNPCGEQPL------------EEYEACNLGHINLSTladkdapdwrvwydnngdaynnlddaaeafiyeAIDMNAFNRRIESGTRFLENVVTMSDFPVDEIEATVRDMRKIGLGIMGLAQLYIQIGVRYGSQEANAIAEQLMTHINHESKWASHELAKERGTFNDWTESKY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2LPU1(1-298:355) Ribonucleotide reductase large subunit n=3 Tax=Euryarchaeota RepID=D2LPU1_9EURY  E=5e-77 s/c=0.98 id=24% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLGSINLSLFVEngkikWDDLRDTVHTAVHFMDNVIDANNYPLPQVAEMTRRSRKIGLGVMGWAEMLIKLGIPYDSEEAVELAEKVMKFINEESHRASMKLAEKRGVFPAWEGSEWWKKGMKIRNATTTTIAPTGTI-------------------------------SIIAGTSSSIEPLFAIAFIRRVLDgqellevnplfeeimkreglyseelmhkvaetGSVQHIDDVPENIKRLFRTAHDIDPV-WHVRMQAAFQKYVDNAVSKTVNLR------HDASISDVEDTYILAWKLKCKgiTIY----RDGSKNVQ-------------------
>UniRef50_A1TJY2(24-382:1226) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=3 Tax=Comamonadaceae RepID=A1TJY2_ACIAC  E=5e-73 s/c=0.77 id=21% cov=34%
---------------------------------------------------------------------------------------------------------------------------------------------------LDVLREKYLKPGEADAET------LYRRVARALASVEAPEVREAIEARFLANLRAGAIG-AGRIMSAAGTAIQaTLINCFVQPVGDCIQgmdeggypGIYEALREAAETMRRGGGVGYDFSRIRPRGAEVKGTASMASGPCSYINVFDQSCATVESAGARRGAQMGVLRIDHPDVLDFITAKRTPG----RWNNFNVSVGVPDAFVQAVLDDAPWELVHPAR----------PGAALREEGARQRADGQWVYRTLPARELWDTIMRSAYDFAEPGILFLDRVNTDNN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1I483(639-942:1121) Ribonucleoside-diphosphate reductase n=1 Tax=Candidatus Desulforudis audaxviator MP104C RepID=B1I483_DESAP  E=3e-62 s/c=0.80 id=23% cov=30%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CLLGSVNLARMlkpgrdgyvVDWELLRDTVRLGIRFLDNLIDVAEYPLEFIAEATRATRKVGLGYTGLHDLLIKMGLPYDAEEGRRFAGTVFKAVQDAALAYSRELAGERGCFPEWERS-----VFHPHEK---------------------------RRNAACITVAPTGSVTTIAGCEGyGIEPIFAVAYTKDTdvagsfevfsplfleacerlgvsrevmsevaRRGGCQGVEGVPPELARIFKGAQEISPRD-HILMQAEVQKYVCNAVSKTINL------PNSATIHDIETCYRLAYELGLK----------------------------------
>UniRef50_Q0A8L7(703-1037:1095) Ribonucleoside-diphosphate reductase n=3 Tax=Ectothiorhodospiraceae RepID=Q0A8L7_ALHEH  E=5e-63 s/c=0.73 id=24% cov=34%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CLLGSVNLTKFvrdpftekarFDWQEYAEVVSVFTRMLDNVVEINGLPLDEQRREIERKRRHGMGFLGLGSTLTMLRMKYGEAESLAFTEKVSREMALAGWRTGVELAEEKGPAPIMDETytvdeamLAKRPEMAVDGYKVGDKVkgrvllaryshYMQRVAEVD-AELVEAIAEKGARFSHHTSIAPTGTISLSLanNASNGIEPSFAHHYFRNViREGRkskekvdvfsfellayrhfidpeaVPSTDPETRNLPDYFITADSVTPK-QHVDIQAAAQKWVDSSISKTANV------PTDYPYEDFKDIYRYAYQQGLK----------------------------------
>UniRef50_C9LEN5(34-490:775) Ribonucleoside-diphosphate reductase n=1 Tax=Prevotella tannerae ATCC 51259 RepID=C9LEN5_9BACT  E=5e-46 s/c=0.41 id=19% cov=43%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHVSLSTPMLAGLGNPHRQapVSDAFTIGFGPkaySYNDLLQADEEEVYLLRRGAALGHDLSRIYPAQLQTEQSEKATPDVVSALERYARS----RQEAARLtacGAITLSLSIKHPDAEAFIDA----GARMRTTAGVNCCLLIDDDFMYAVAKGESYRQQFPVD-----------------------AESPLLATNIDARRLWEKLLRKAMRNEAPEIHFSD-----NMLKEQLAGCYA----GARPQALAATLNATIPLATYDSSRLLTVNLYsyveqpfteqAIFDHKLFRRHLFLVQRLADDLVDIeeekidsmlqniadAEVPaeakmieqklWEKVRRHLLTYRPTGLLLTGEAETLAALGLSQDTPAAGAHTRALKQSLAIATCESTVKMAEERGAFSDYD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2LQG3(19-305:305) ATP-cone domain protein (Fragment) n=1 Tax=Aciduliprofundum boonei T469 RepID=D2LQG3_9EURY  E=1e-36 s/c=0.55 id=20% cov=29%
----MKVIKRDGRIVDFSEDKIFQAIMKAMNsigGYGEEDAQRVTRKVVEKIKESrverITVEKIQDIVEET-------------------LMLEGYINVAKSY---------------------ILYREERRKIRQAKKVIGVQDDLKLTVNAIKVLEARYLLKDE-NGNVIETPRQMFERTARYLALVDifyeddiydkegkqkerkidveekpeflsiwefnmlkraftyfskegymkvdfsyvldslkSKWDKIERVKnKFAEVMLHRKYVPNSPTLMNANTKLGQLSACFVLPVPDSIEGIFNAVKYAAMIHKSGGGTGFSFSRLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6Q367(24-580:650) Probable adenosylcobalamin-dependent ribonucleoside-triphosphate reductase n=1 Tax=Nitratiruptor sp. SB155-2 RepID=RTPR_NITSB  E=2e-30 s/c=0.24 id=20% cov=30%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DYSKIRPAGSPLKTFGGIAPGPEPLKRL-------------------------HKKIEQILDDYLDKKIDKTRCvVDLfnNIGLCVVSGNIRRSAE------IAIGRPGDKTFLHLKDYEKFpERKEYGWISNNSVVIENLDDFHYIDAITSLIASNGEPGVLHLENMQKYGRFGEIVpDRAWLSNPCGEIALESYE------------LCNLSEIFISKCSNEEDFQKLIEYATFYASTV---NLLPThrPETNEIIARNRRIGVSVSGVADAIEKFGL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9G0G5(176-670:671) RP ribonucleotide reductase n=6 Tax=root RepID=Q9G0G5_9CAUD   E=4e-13 s/c=0.16 id=24% cov=31%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLVEVDWGKFLgDHGGLERAVWLAARAnyrqtcvnLDDgVLQRSWHEL------NEFLRLCGVGGTGIVKFL-------DHYTGRNNVASMLQSLRAQAHKGANSMAEEFGT------------PMPK----------------------------------AVTTVKPSGTLSKIMDTTEGVHkplgkyiinnitfskddPIIAsleaagyKVFDKPFEPSSKLVAMPVcYDDVSFDEV---ETDRGTVHVNLESAVEQldrykllmdnYVDHNCSVTISYDPSEVPaiidwiltnwdtyvgvsfiyrnDPTKTAEDLGYAYLpqeviteEAY------VAYTSQLKPLDLSGLTSDDDLVDEACATGACPI
>UniRef50_A6TN19(4-518:710) Anaerobic ribonucleoside-triphosphate reductase n=23 Tax=cellular organisms RepID=A6TN19_ALKMQ  E=2e-05 s/c=0.11 id=15% cov=62%
----MKVQKRNGEIVDFDAIKIKEAIFSAAKSVGG--------------KDEMTASRLSKLAVDIVSETYAANIPsveDIQDIVEKVLIEEGHAKTAKSYILYRKKQKDIREVKNLFMDAEVM---VEEYVNLEDWRVNENANMGFSLQGL-------------NNHIVESITKKYW-----LNKIYTKELRDAHIQGDLHIHDLGLLAP----------------YCCGWDLEAFLKDGFKGAKG-----KVESKPPKHFeSALGQLVNLLYTLQGEAAGaqAVSSIDTYLAPFIYYD--------KMSYEQVKKA-IQRFVFNLNVPTRVGFQTPFTNVTLDItPHELLKkqRVIIGGENMDKNYGEFQKEMDLFNMAFCEVMMEGDGAGRAFSFPIPTVNItkdfpwdTEVVNAIMEMTRKFGTPY--FANFIN--SDMAPEDIRSMCCRLRLDNRELRKRGGGLFGANPLTGSINVVTLNMARIgytsKNMEEFKSKVRELMqnakqicedkrVILEQYMDVGLYPysryyLRDVKSATGEYfknhfSTIGLNGMNEA-CLNLLGVDITTEEGNEFAVEIMEFM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8P6Y3(10-778:1061) Ribonucleoside-diphosphate reductase n=1 Tax=Brugia malayi RepID=A8P6Y3_BRUMA  E=0 s/c=1.03 id=30% cov=93%
---NSYVVKRDGRHEAVSFDKIARRIMKLCYGLsqDRVDHIEISQKVIAGLYKGVTTVELDNLAAEIAADMITK-HPDYATLASRITVSNLHKKTEKSFSKLSRRLYNATHPKSGRHMPLIskeLFDIIQNNANLLDSAIVHERDYLYTYFGLKTLERSYLLQ--INGELAERPQHMLMRVALGIHG-----EDIEAALETYNLMSERWFTHATPTLFNSGTCTPQMSSCFLLTMfEDSIEGIFETLKKCALISKSAGGIGLNVHCIRASGSAIAGTNGVSNGLVPMLRVFNNAARYVDQGGnKRPGAFAVYLEPWHADIFDFLELRKNVGDELERCRDLFFGLWVPDLFMERVRDDKIWSLMCPAECPGLEDSW---GEAFEKLYTQYEEEGRYRKQ-VPARKLWETIVFTQIETGMPYMVYKDTCNRKTN-QQNLGTIKCSNLCTEVVLYSSR--------EEIAVCNLASIALGRFvtsemkYDFKMLHEVTKVVVKNLNKVIDRNYYPIPEAERSNKRHRPIGIGVQGLADAFILMRYPFTSEKARDLNKRIFETIYYAALEASCDLAKEQGPYESYEGSPISKGILQFDMWGVTPTD------QCDWGTLREKIAKFGIRNSVLLSPMPTASTAQILGNNESIEPYTSNVYTRNVLSGSFqifnmhlmndlmhldlwdddmkleiiknkgsiQNIERIPQEIRDLYRTVWEMS-QRDIIDMAADRGAFIDQSQSLNIFIARPNYGN-------ITSMHFYGWQkvctaflmyKGLKTgMYYLRTRPAVDAVQFTVDKT-------------
>UniRef50_A8URA6(1-767:767) Ribonucleoside-diphosphate reductase n=1 Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8URA6_9AQUI  E=0 s/c=1.03 id=30% cov=97%
----MEVVKRSGKREQLDINKIRIALEFAFKGLN-VDPLELETDAQIQFRDGITTEEIQAVLIRTAAEKVSPETPDWQFAAARLLLYDLYKKVahirgyevrdelskdYKPYNTEGFYEFINRFVGEGIYGDYLLKHYSESDIRDLAKHIKPERDLYFNYTGIKILTDRYLARDE-DGRIIELPQEMYMLISMTLAIPEKEGDRVKWAKEFYDLLSEHLITVATPTLMNARRPFTQLSSCFILTVDDDLYDIFDNVQKAAQISKHAGGLGIYIGKLRATGAPIRKFKGASSGIIPVVKVINDVMTYVDQLGMRKGSASITLDIWHKDILDFLEVKTNAGDERKKAHDIHPAISIPDLFMKRVKNREKWTLLDPYYTKNVRDGKNLEdlwGEAFEEEYERLEKElPEDAKKEVDAFELWKRLLTVAFETGEPYLFFRDHANRINP-NKHAGMVYSSNLCHEIVQNMSPTKHLGKEldpetgeivhrkkSGDVVVCNLGSVNLGKVYTKETMEQVVPKLVRLLDNVIEMNYYAIPEAEYTNKRYRAIGIGVSNYHYCLVKNGVNWESEDHLKFADKLFELLGFYAIKGSMELAKERGKYRLFEGSDWSRGIFFGRKAEELEENSKENGNDLPWKDLAEDVRENGIRNSYLLALMPTGSTSLILGATPSVDPIFAKYYKEENMSGILPQVPPEIDRFFWHYKSAYNI-DQEWVVRAAAVRQKWIDQAQSLNLFID-----PEKIDGPTLSKIYQLAWELGLKTIYYLRSKSITDI-----------EECESCAV--
>UniRef50_B2SYU1(156-922:1001) Ribonucleoside-diphosphate reductase n=15 Tax=cellular organisms RepID=B2SYU1_BURPP  E=0 s/c=0.98 id=29% cov=94%
----------NGVTRPLDMAALRGIIELACSNLGDaVSADPIIAETVKNLYDGVPMSQVYDSAILAARTMIEKD-PAYSQVTARILLHTIRREILKEEVTQTemgerYAEYFPQFIKRGVQAELLDDKLLQFDLKRLGAALDNNRDLQFGYLGLQTLYDRYFLHH--DGVRIEMPQAFFMRVAMGLSLNE--IDREARAIEFYNVLSSFDFMSSTPTLFNSGTRRSQLSSCYLTTVDDDLDGIYEALKENALLSKFAGGLGNDWTRVRALGSHIKGTNGKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLESWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVMEGGDWTLFSPSTCPDLHDLFGADFEKAYTAYEDKVARGEIKlFKKIPAAQLWRKMLGMLFETGHPWITFKDPCNVRSP-QQHVGVVHSSNLCTEITLNTS--------DAEIAVCNLGSVNLVAHlkeqadgtlvLDHDKLKRTVSVAMRMLDNVIDINYYAVAKARNSNLKHRPVGMGIMGFQDCLHLLRTPYASEEAVKFADTSMEAVCYYAYYASTELAQERGRYSSYRGSLWDRGILPQDSVKLLADArggyvEVDSSESMDWTELRSRIATYGMRNSNCVAIAPTATISNIIGVSACIEPTFQNLYVKSNLSGEFTVVNDYlvrdlkarglwdevmvadlkyfdgtlsridriPADLRAIYATAFEVDPK-WLVEAASRRQKWIDQAQSLNIYM-------GGASGKKLDEIYKLAWVRGLKTTYYLRTMAATHVEKST-----------------
>UniRef50_Q8K9W3(1-763:763) Ribonucleoside-diphosphate reductase subunit alpha n=180 Tax=root RepID=RIR1_BUCAP  E=0 s/c=0.99 id=73% cov=100%
MKNSLFVTKRNGKKEKINLDKIHKVLNWAAKGLENISVSQVELRSRIQFYNNISTVNIHETIIKAAADLISENTPDYQYMAARLAIFHLRKKAYGQFEPPNLYYHVKKMVQLGKYDEKLLQNYSFEEYVEMNSFVDHRRDMNFSYAAVKQLEAKYLLQNRVTGQIYESAQFLYILISACLFSKYEKKVRMNYIQRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECADNLNSINATTSAIVKYVSQRAGIGINAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGGVRGGAATVFYPIWHLEIESLLVLKNNRGIEENRVRHLDYAVQINKLMYQRMLLGQKITLFSPSDVPKLYEFFFSDQKKFKEIYIKYEKNRNIRKKSINAIDLFCLIMRERASTGRIYIQHVDHCNSHSAFNSKLATIRQSNLCLEITLPTKPLNNIDDKNGEIALCTLSALNLGLINDLHDLKELSTLSVRALDEILEYQNYPVVCAKKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAKNLTHKTFEAIQYYLLKASCELAKEKGSCSLFNQTNYYLGKFPIDTYKKDIDSICNEPLHLNWNLLRKKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRGFISIKSSKDGMLRQVVPEYKKLKSEYELLWEIPNNIGYLELVAIMQKFVDQSISANTNYDPKRFLNEKIPMKQLIYDLLVAYKLGIKTLYYQNTRDGAEDNQNLnkSIENIKEDNCTSGSCTI
>UniRef50_Q75BW6(5-793:864) Ribonucleoside-diphosphate reductase n=2 Tax=Saccharomycetaceae RepID=Q75BW6_ASHGO  E=0 s/c=0.94 id=29% cov=96%
-KKIFIISDDSGLTEAFDERKLLESLRKLQFGLkiNDADIDKAVKRIAAGIGGDIRDSELVAYIGETLASMITR-HPDFSLLAARVEIKVLHKRLLGLGFTGNLavlcesgdspeghatKRKRAMSPCTRGPVRRELYDLAVQHRNIIDQAIDDTLDFTFTYFGWKTLCKSYLLKHQ--GRVHETPQYMFMRVALALHG---PSGDIDRVLETYRLMANKYFIHASPTLFNAGTTSQFLSSCFLLGIhEDSIDGIYNALHKAALISKASGGIGIHVSDIRANGSYISGTNGTSNGLVPMLSVFNSTARYVDQGGnKRPGAFCIYLEPWHADVFDFLRLRRNHGKEEMRARDLFYGLWIPDLFMKRVENNGEWSLFSPNEAVGLSDCY---GEAFEQLYVRYERELE-PYRRVKAQELWREILLSQTETGGPFMLYKDACNSKSN-QKNLGTIKSSNLCCEIVEYSSR--------DEVAVCNLASVALPTFvsvtsdaitFDYARLHSVVKVMTRNLDKAIDIGDYPVPEAERSNKKHRPLALGVQGLADVFMLMRFPFNGEEAAQMNREIFETIYHAAVETSIELAAEYGVYASFVGSPASKGELQFDLWGRNKDNY--QFLYDDWDELKEKIKSGpGLRNSLLVGPMPTASTSQILGFTESFEPMTSMIYTRRVLSGEYtlvnkymvqdfcdlgiwseelknriikdggsiQGIDGIPPDLKDLYKTVWEL-PQRKLIDLSADRAPFVDQSQSLNLFLKEP-------TMGKLTSMHFYAWKKGLKTgMYYLRTQAAANAIQFTLT----DENTLSGPVKL
>UniRef50_C0QPQ0(4-773:847) Ribonucleoside-diphosphate reductase n=2 Tax=Hydrogenothermaceae RepID=C0QPQ0_PERMH  E=0 s/c=0.84 id=25% cov=84%
------IRKRDGRIVPFNPEKITNAIWKAMQAVGEKDFSTAEK----------ISKEVVRELERT---LKPGEIPDVEQIQDIVERKLIEAGLARVAKAYILYRQKR-------------AEIRKEKQQILNKKEIDEVDKRFDINALRVLAARYLNKDRA-GKIIESPKQLFQRVAVntalpsllydervyskkelkkqpvedfdperyegklkigdytlnryHLEGLKRVYDRLNNERRmkipfskllkmiekgdfesygreidqYYSIMVEKKFMPNTPVLVNFGNPLGMGMACFVLDMEDSIESIMETLKRAALIFKAGGGCGYNFSKLRPKGDFISTTHGKSSGPIAFMTLYDKMTDVIKQGGVRRGANMGILNSDHPDIEEFIVAKKGN----VQLTNFNISVFLKEDFWDYYRENKPYPLINPRDGK--------------------------VWKYVNPRNLFDTIVYEGWESAEPGLLFDDNINRYNPFLETFGRIQATNPCGEVLLYP------------NESCDLGSINLWAFikeyydgngrkveVDWDGLEKTVRIATRFLDNVLDINKYPFKEIEKETLKNRKIGLGIMGLADFLFELEIPYNSEDGRRWMERVMEFVNYYSKEESIQLAKERGKFPSYNKSFYRKGKLPIRGFEEK------ESWNLDWDKLIDKIKKHGLRNAFTTVIAPTGSISMIAGTTSGIEPIFALVYEKKVTVGTFYYVDPvfektmeregifddtlikdvsknegsiqdikyIPEKWKKVFVTAMDISAED-HVKALASVQKWTDSSVSKTINF------PEDATVEDMKRAYLLAHYLGCKglTVY-------------------------------
>UniRef50_B8J271(20-598:781) Ribonucleoside-diphosphate reductase n=11 Tax=Bacteria RepID=B8J271_DESDA  E=1e-168 s/c=1.03 id=26% cov=67%
------------------------------------------------------------------------------------------------------------------------------------------------------LQKRYLRKN-LDGKIIEAPRDLFWRVAAAIAAQEENYKNSsrtpnQLARDFYDLMTSWKFLPNSPTLMNAGTELGQLSACFVLPVGDSIEEIFDAVKYAAMIHKSGGGTGFSFSRLRPKDSRVGSTGGVASGPVSFLRIFNTATEQIKQGGTRRGANMGILRVDHPDILEFIRAKEKEGE----FNNFNLSVGLTESFMQAVENDEQYDLVSP--------------------------NNGEVMKRLPARDVFDLLVRKAWQSGDPGIVFLDRINRDNPTPDQ-GEIESTNPCGEQPLLP------------FEACNLGSINLSCFhvpghensadpaagIDWDELRRVVHLSVRFLDNVIDASRFPLDRIGETVRKNRKIGLGVMGFADLLFQLGVPYDSQQGLDLGERIMAFVQGEGHRASAELALERGPFPAYGSSVFARKKL------------------------------GPYRNATVTTIAPTGTLSIIAGCSSGVEPLFALCFTRNILDGErLVEINPHFEAalesgglfshelmdavvakgsiqdmdylpapLRKTFVTAMDIAPQ-WHLRMQAAFQRHTDNAVSKTVNL------SNSATEQDIREIYWLAYQEGCKgvTVY----RDGCKSIQ-------------------
>UniRef50_D1CDG6(20-605:811) Ribonucleoside-diphosphate reductase n=1 Tax=Thermobaculum terrenum ATCC BAA-798 RepID=D1CDG6_THET1  E=1e-163 s/c=0.98 id=23% cov=69%
----------------------------------------------------------------------------------------------------------------------------------------------------KIFLDRYARKDPNGTPLEHYPEEMWLRVAKAIAAVEPnPEAQRQWTLRFYDILQGFRFVPGGRILSGAGSGAEvTYYNCFVIPsPEDSVEGIFRNITTAAHIMRRSGGVGVNLSSLRPRGAYIKTVNGTSSGPCSWAILYSDMTgKVIIQGGSRRGALMIMLDDDHPDIEEFVEYKRKNP---GHIDHANLSVAVSDAFMEAVKKDLPWDL------------------KWQGK----------VWKTIRARDLWRKIAESAWAYAEPGLVFIDRYNKRSNT-WYFENIRCVNPCGEQGLPPW------------GVCNLGALNLLAFvkhidgetyFDFEDLANTARVAIRFLDNVIDATVYPFPENEEAQKhGARRTGLGTMGLADVLIKLGVKYGSPEAEPLVERIYRTIRDAAYDASADLAAEKGPFPKFDRDKYMQGEF----------------IRELPEEIQAKIRRQGIRNAVLLTQAPTGTTSSLAGVNSGIEPVFAFVTKRRDRLGEHLLYHPLAQEwmdahpgkpLPDYFVSSADLTPEE-HIRIQAVVQKYTDSSISKTVN------GPEDNTVEDVERLYMLAYDTGCKGITYYRqgSRDA------------------------
>UniRef50_Q1IXG5(1-649:649) Ribonucleoside-diphosphate reductase n=6 Tax=Bacteria RepID=Q1IXG5_DEIGD  E=1e-158 s/c=0.87 id=25% cov=81%
------------------------------------------------------------------------------------------------------------MVERGFWDGEMLARYRPEEVKAVFNRAYSHRFRFQSFMGAQKFYAEYATKTPDGSRYLERYEDRMSMVALARAG-----GNAELALTLVDHLVRQTFVPATPTLMNSGKaNTGRLTSCFLLqDCTDSLDSIMKTQHFAADLSKNGGGVGIDLSNLRARGESLRHLQGVTKGAAAVAKLFDVLFRYADQAGQRQGAAVVNLNVMHPDFQELLAGKKIATDEDARLKTLSICAVIPDVFMQAVRDDKDVYQVYPRSYEQATGRIFTDID-WDTEYASIVENPNIRKRRVSARQLLQEIALTQGESGYPYLLFTGNANRANPV-PNVGTVKMTNLCSEIMQPTLPSsfhpygEEARDEIGLDVSCNLASLHIGNALKSGDLGGVVRAAISMLDDVAQSTNItEVPAVARANREMRSIGLGAMGLHGHLAEHGIAYGSPEALAFCDLFFEAVHFHARRASMELARDTGfVFAGFQGSRYQSGEYFAPYTEREREPAQDlapevraalqgawLPTREDWRQLVSDIQRYGLAHSHVMAIAPTGSISYVANATASVMPITERVETRTSGKGKTIYPMPGLnEQTEWFYEEAYDMDM-RRVIDTVATIQRHVDQGISCTLFVR------SNVTTADLARLYISAYRKGLKSLYYLRQRRA------------------------
>UniRef50_P26685(6-777:779) Ribonucleoside-diphosphate reductase large subunit n=7 Tax=African swine fever virus RepID=RIR1_ASFM2  E=1e-152 s/c=0.70 id=27% cov=87%
---------------------------------------------------------------------------DYSTLAARLSVYLLHQSTASSFSKAVSLQAAQSCSRLSSHFVDVVYKYK----AIFDSYIDYSRDYKLSLLGIETMKNSYLLKNK-DGVIMERPQDAYMRVAIMIHG-MGRVVNMKMILLTYDLLSRHVITHASPTMFNAGTKKPQLSSCFLLNVNDNLENLYDMVKTAGIISGGGGGIGLCLSGIRAKNSFISGSGLRSNGIQNYIVLQNASQCYANQGGLRPGAYAVYLELWHQDIFTFLQmprLKGQMAEQRLNAPNLKYGLWVPDLFMEILEDqihnrgDGTWYLFSPDQAPNLHKVFDLERsqhenahREFKKLYYQYVAEKRYTGVT-TAKEIIKEWFKTVVQVGNPYIGFKDAINRKSNL-SHVGTITNSNLCIEITIPCWEGN-----EAEQGVCNLAAVNLAAFiressYDYRGLIEAAGNVTENLDNIIDNGYYPTEATRRSNMRHRPIGIGVFGLADVFASLKMKFGSPEAIAIDEAIHAALYYGAMRRSIELAKEKGSHPSFPGSAASKGLLQPDLWVRCGDLIPSWENRvaqttqgvltpKKWWQLR-LAAIQGVRNGYLTALMPTATSSNSTGKNECFEPFTSNLYTRRTLSGEFiilnkylmddleeinlwsediqqqllnaggsiQHILDIPAEIRERYKTSREM-NQKILTKHAAARNPFVSQSMSLNYYFYEPE-------LSQVLTVLVLGWKKGLTTgSYYCHFSPGAG-TQKKIIRNSEkacNADCEAC----
>UniRef50_O26748(4-682:703) Ribonucleoside-diphosphate reductase n=1 Tax=Methanothermobacter thermautotrophicus str. Delta H RepID=O26748_METTH  E=1e-151 s/c=0.79 id=24% cov=63%
--------------------------------------------------------------------------------------------------------------------------------------------------ALKVLEERYLLRGE-GGEVVETPEEMFRRVARAVASADEAYGDDPAVAEeaFYSVMGNLEFLPNSPTLMNAGTPINQLSACFVLPVEDSIDSIFSSLRDMAIIHKSGGGVGFSFSRLRPRGDIVASTMGVASGPVSFMRIFDVAVDVIKQGGRRRGANMGVLHVSHPDIFSFIDAKSREGP----LRNFNLSVAVPDEFM----DDRPVDLINP-------------------------RNGEVV-DSVESRVILKRIVEAAWRSGDPGILFEDRINRYNPT-PQLGRIEATNPCVsgdTIVMTSGGPRTVAELEGKpftalirgsgypcpsgffrtcerdvydlrtreghclrlthdhrvlvmdgglewraagelergdrlvmddaagefpalatfrglrgagrqdvydatvygasaftangfivhncgeqplltHESCNLGSVNLSLMVgpsgiNWEKLRRTIHVAVHFLDNVIDVNSYPLRPVEEMTLRTRKIGLGVMGFADMLIKLGIPYNSVAALEVAGRVMSFISSEARRASMELARERGSFPEFKGSIWDIQGFEC------------------------------MRNATLTTIAPTGSLSIIAGTSSGIEPLFAVSFTRNILGrsfhelhplfktmagrldkrsleaiesrGSLRGVPGVPARIRRLFVTAHEIDPVF-HVKMQAAFQRYVDNAVS-------------------------------------------------------------------
>UniRef50_P78027(58-719:721) Ribonucleoside-diphosphate reductase subunit alpha n=50 Tax=Bacteria RepID=RIR1_MYCPN  E=1e-150 s/c=0.81 id=25% cov=83%
------------------------------------------------------------------------------------------------------------LVKNDYYDENIINMYSFEQFEEITRKAYAYRFRYANFMGAFKFYNAYALKTFDGKWYLENYEDRVVMNVLFLA-----NGNYNKALKLLKQIITNRFQPATPTFLNAGrKKRGEFVSCYLLRIEDNMESIGRAITTTLQLSKRDGGVALLLTNIRESGAPIKKIENQSSGIIPIMKLLEDSFSYANQLGQRQGAGAVYLHAHHPDVMQFLDTKRENADEKIRIKSLSLGLVIPDITFTLAKNNEEMALFSPYDVYEEYGKPLSDIS-VTEMYYELLANQRIKKTFINARKFFQTVAELHFESGYPYILFDDTVNRRNA---HPNRIVMSNLCSEIVQPSTPSEFHHDlafkKVGNDISCNLGSLNIAKAMESGpEFSELVKLAIESLDLVSRVSNLETaPSIQKGNSENHALGLGAMNLHGFLATNQIYYNSPEAIDFTNIFFYTVAYHAFKASSELALEKGKFKNFENTKFADGSY-FDKYIKVEPDFwtpktervkalfqkyqVEIPTRENWKELALNIQKNGLANSHLLAIAPTGSISYLSSCTPSLQPVVSPVEVRK--EGRLGRIyVPAYQLNKDSYPfykdGAYELGP-EPIINIAAAAQQHVDQAISLTLFMTD------KATTRDLNKAYIYAFKKGCSSIYYVRVRQ--EVLEDSEDHTIQMQQCEAC----
>UniRef50_Q66LW9(38-788:811) Ribonucleoside-diphosphate reductase 1 alpha chain n=4 Tax=Siphoviridae RepID=Q66LW9_BPT5  E=1e-147 s/c=0.70 id=39% cov=94%
------VIKRDGTVEDFAPEKLNGWAEYGCKTVD-VSWSAITMAAQKTLPKGVVDSDtLMDALIKAAESLI-KDNPAYDVPAKELRLAQMRKRLYDSFEPPSLRFFHDHMVSVGAWE-DMSAWITDEQFEALNQVIDHDRDRLFTSGGLKQFFDKYSRRNIATGEIYETPQFAYMGMAMAMLS--QPNWTILDAIDLYNAMSLHKINVPTPPLVGLRSSDRGFASCCLVDSTDTLDSIDTAEHIVFKMVAARAGIGYHLES-RSIADPVRNGAFPHSGKLPYYRHIDRSVKANTQ-QTRGGSATVSYPYFDPEIIQLMQVKQQRATDENKIDKMDYSLSFNNLLLKRYLKNEDITLMSYFYAPEVHEAFYSDDEaKFEEIYVAAEKrvasltkidhegKTVPTAPKVSAKEILDTWLRIRMETGRMYAHHIGESNRHGNF---LDPIRMTNLCVEITQPTRPFHHITelyktkeqldqmkpEDIGEVSLCNLGGVVLGRMESLAEWEKTCYILLKFVDTIIEIQDYPFPTMEYTAKKRRNVGIGLMNAAGAMAAEGLAYEGIEARNWIHREAEKLSYFLHKASVRLAKEQGACEWFNRTKPSKGILVIDTYKKTVDELVSVGLEMDWESLRADILKYGMRNSVLTAQMPGESSSVLLGVTNSIEPPRKIVSIKGSAVNKVIAIAPgatDWETLM-SYKLAYDVDRIEW-IKWVATMQKFFSQSISTNMYYDYTKFENEIIPGPVVVRDFMTAVKYGWKTWYYAN----------------------------
>UniRef50_D2XAL3(29-915:916) Ribonucleoside diphosphate reductase alpha subunit n=1 Tax=Marseillevirus RepID=D2XAL3_9VIRU  E=1e-139 s/c=0.56 id=26% cov=86%
----------------------------------------------------------------------SFIHPDWGVLAGRAEIRKLWSETPEKFSQMAK--------GMKSVLDEKFYEFVASHSQELDNICSHERDNRFDWMAINTLEKSYLLKKKcfdGKLRVFERPQHMYLRVATQLWMP-----DVQKIKEFYDGLSLGFYTVASPIFFNAGLKKFSGSSCFLGKIPDDLIGIIDTWKQMAIISSRSGGVGYSASSVRH--SDIGGGLGESSGVVSLLRVPDAVLGYVDQGGRRKGSGTFFLACWHIDIFTFVDAKKPGGDDLKKARQLFYAIWTSDLFMKRVETDGNWSLFCPKEAPGLDEIY---GKDFEDLYERYEKEGR-ARTTVKAQELWHHILVAQAEVGMPFIVYKDAICRKNN-QKHTGIPHSLNLCVAgntriltkekghveiesvmgqelhvwngeewsltkiirtatnqdllkvefsngavlectpqhrffverehkilevrtvnlkegeclegwkVPENPKIFEEgvrvvsvsegrknmdtfcfkeekrgrgmfegivtgqcleitENTSDEEIASCNLSSVCLNSFvdkeskkYDFGALASSVRFIVRSLNNVVDRNYYPseLPSIKTTNLRHRPLGIGVQGLADTFAMMDICWGDEEARNLNRKIFETMYHAAVTESRKISKERASlgfqtpyYETFPGSPLSKGFFAHDLWDaealhkesgipfdsitveqvksyRKKKGIPESFCGFDWDKERLETMRDGVYNSLLIALMPTASTAQILRNNESFEAFTSIIGKRTVLSGAFAVVNrhfiddmiglgvwnkknmliclkgqgsvqgittdditkfERLEHIKRKYLNAFELS-QKRLCQLGIDRSRYVCQSSSHNCFMRNP-------TYQKLTSYHFFQWENGAKTgMYYLRTSAPGVA-----VSVAAEAECLMCS---
>UniRef50_A4VFR5(55-712:745) Ribonucleoside-diphosphate reductase n=32 Tax=Proteobacteria RepID=A4VFR5_PSEU5  E=1e-137 s/c=0.75 id=23% cov=72%
--------------------------------------------------------------------------------------------------------------------------------------------------------QKYRLSSKDGTPIDQTVDDTWQRVARALADVEPAKQREHWYERFLWALRNGA-IPAGRIISNAGaqdyKPATSTINCTVSgSITDSMDDILGKVHEAGLTLKAGCGIGYEFSTLRPRGSFVSGAGAHTSGPLSFMDIFDKMCFTVSSAGGRRGAQMGTFDVGHPDVREFIRAKR----EDGRLRQFNLSLLITDEFMQTVEADGEWPLIFPVHAKEAAELDLADdaqviWREWPVHDGYIVRDDGLVackiYGRVKARHLWDMIMVSTYDYAEPGFILIDRVNQLNN-NWWCEAIRATNPCGEQPLPPY------------GSCLLGSINLTHFvidpfgvearFDWDKYREVVRVFTRMLDNVVEINGLPLEQQRHEIESKRRHGMGFLGLGSTLTLLKLRYGSPEACVFTEEVSREMALVGWEQALELSKEKGPAPLLSQNfevtaemLRKRPEMAKDGYKVG-DQIAGRVLHAKYSRYMQKIAEYapdliealaeqGARFTHHSSIAPTGTISLSLanNASNGIEPSFAHHYSRNlIRPGRkakekievfsyellayrtlinaraKPGSDEPGEKLPDYFITADDVSPT-QHVDIQAAAQKWVDSSISKTANV------PTDYPFEAFKDIYRYAWRQGLK----------------------------------
>UniRef50_A0MN59(12-762:797) Ribonucleotide reductase alpha subunit n=1 Tax=Thermus phage phiYS40 RepID=A0MN59_9CAUD  E=1e-124 s/c=0.60 id=23% cov=81%
-------------------------------------------------------------------------------------------------------DTFEKFLEYGEPENALTKEEINNVFTELEKlgLIEEIKDELSSFYKVKKedlidgffvqnisseiYKQKYQLKDGKNKNelVDLTPYHTFVRVALAVALVNARYSKrlekygldafktfVDDFLSFFYILATGRSTGAGRVMSNAGsklyKTYTTLINCTVMrQIPDSMHGIMETLTEASLTLKAGAGTGYDFSSIRPKGAFVHGAGAETSGVVSFAEIFDKMCSTIMSAGGRRGAQMLVIDVRHPESIDLFMAKRNDGV----LRYFNISLLFPNSLMEKVKNDEEfeqwfWTFemtFTPSEVIEKNGNNvffigdkevvivengklPYEYEEYDyfafgedhqvMKYENFGKDkyriyKKEVFKRVRAREIYDIVMQSTYDYAEPGIIFIDNVNNKNVLKGK-EYIRATNPCGEQPLPPY------------GSCNLGSIFLHRFvkepfnydlkpeenFDFDKLFEVSRLMNRFLDFVNDITNLPLVQLKEAAFTKRRHGLGISGIADTLIMVGLRYGSEEAAKFLEKIMYTIQLASAVENVRMADIYGPAPV--GVTLKEWVDVFGHLKEKLEEIYG-----------EDFYKLPLRYSHAISIAPTGTISLTFGNNvaNGIEPTFALSYMRNIRlPGKKTKTQEEVYSFaailfknyfghtnyNEYFVTTNDI-TVDEHIRMQASAQKYVDSAISKTCNV------PTDYPFEMFKEAYIKAYELGLKgfTTFRFNPKFsvGVLVKKDDLENLLIEFETDTG----
>UniRef50_C9MSK4(59-698:902) Ribonucleoside-diphosphate reductase n=8 Tax=Prevotella RepID=C9MSK4_9BACT  E=1e-122 s/c=0.69 id=22% cov=69%
--------------------------------------------------------------------------------------------------------------------------------------------------------NKYAMKDSLGNIYEKSPEQMHRRIAKEIARIEHKYKNPLTEEEIFNLLDHFRYiIPAGSPMTGIGNDHQvaSLSNCFVIGLDgdaDSYGAILRIDEEQVQLMKRRGGVGHDLSHIRPKGSPVHNSALTSTGLVPFMERYSNSTREVAQDG-RRGALMLSVSIKHPDSEAFIDAKM----EEGKVTGANVSVKITDEFMRAAIDDKPYEQQFPIDSTE-----------------------PKCTKKVSAKALWEKIVHNAWKSAEPGVLFWDTIIRESIPDCYADlgfRTVSTNPCGEIPLCPY------------DSCRLLSLNLYsyvldpftdhACFDFDLFSKHAQLAQRIMDDIVDLemekidlimakvksdpqvdevkeaEYHLWEKIKDKSGKGRRTGVGITAEGDMIAAMGLRYGTQEATDFSVSVHRALALNAYRSSVRMAEERGAFAIYDA-------------KREEHNPFILRLKEADAQLYEEMIRYGRRNIACLTIAPTGTTSLMTQTTSGIEPVFMPVYKRRrkVNPNDTDVHVDFVDEVGDSFEeyivyhrkflTWMEVngidtqkkysqeeidtlvkrspyykataNDVDWLmkVRMQGTIQKWVDHSISVTVNL------PNSVDEALVNKLYVEAWRSGCKgcTIYRDGSRSG------------------------
>UniRef50_A2BL44(13-908:991) Ribonucleoside-diphosphate reductase n=2 Tax=Desulfurococcales RepID=A2BL44_HYPBU  E=1e-119 s/c=0.48 id=24% cov=75%
-------------------------------------------------------------------------------------------------------------------------------------------DKGFTYNAIRVLLARYMVRNEY-GVPMETPSMVMARVAWGF------STRVDPV-KLYRLLIARKFMFNSPTLFNMyvDGAYGTLSACYVTPVYDDMKAIMDAATVQAMTFKWGGGQGFSFSELRPRWDIVRSTGGQASGPLSFMQIYDMVTETVKQGGKRRGANMGIMHAWHPDIYNphfnpwhalrnmlppqlkalidttkrliehleregyeidpvykeivmrlseegwetvedagFIQAKEPPLQDAN-LTNFNISVAANDAFMQAILRGEDWWMVNPRysdsgdgvyrlhysvsratglgrlgellerypwllenpylnifeDVLEEAKTKALEALKEQARYTGWETSPEqknPYAWKYPARKLWEKIVENAWASGDPGLFFPDNHNKWNPT-PWLGAVYATNPCGEQPLYP------------FESCNLGSMSIDKYisdgkFDLAQFMSDIQLAVDSMDAVIDFNKHPDPRQTVANKFTRKIGLGIMGLADALAKLGYPYDSEEAVAFTLIVMAALEVYSWKRSWELGAKLGHAPAFEcrrydwksmrcvekaepeelvelhtpallkasrisrvedgwlKVCYHAVEIPEDMLERLVGEAKSRIEPNgtvklvRWEAVekvlrevfgvtREDyeralrsspvivvnspklllalavynpeaawkvLKAYGRslgarapRNTVMTTVAPTGTISIIAGTSSGIEPYFALVYRRVVAIGEFLEVVKpfreklleaarrynvPLDAVKVVYETigrhkgslrwalgevrekliqmgimngflaeveklarlfTMSMDFDLWyHLAHQIAAQLYVDQAISKTINLRK------DATKDEVYTAYLVAWLGGLKgvTVY----RDESKGVQ-------------------
>UniRef50_D1Y8J0(2-700:894) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Pyramidobacter piscolens W5455 RepID=D1Y8J0_9BACT  E=1e-117 s/c=0.61 id=23% cov=62%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDNQQLFACFVIDIPDSIEGIFDSVRAAAVISKYGGGVGGNFGRLRERGADIKgGTGGKASGPVSFMETWNTMGCVVVQGGRRRAALMGMLPDDHPDIEQFMDAKT----EEGKLSYFNISVCVSDELVGAAREKRPFALRSR-------------------------ANGKVVR-TVSGDELWNKLCQNAWRRGDPGVFFIDRANDDNLLKLSGDFdIESTNPCGEQPLPTYT------------SCNLGSVNLVKFvrpdetgrqsFDMEGFMDQVYRSIYYLDLVIDATSYPLQRIGERTKRIRPVGLGLMGLADAAILSGDVYGSESFKSFCDSLGAHMAGAALMATVDAVAHMGKEP-FSESfavarlfeeehRAHGGELFARQWIDEMDlnsyrefiarmrthgqvpytllntleilpDVLGDEALPELKRLMTALLEGKLRNSRRLSIAPTGSISMIFDSSAGIEPNFAWRWSRKVMksDGDGWEVREYFhplitqkeaDELRgsgvisdPRYVTAYDISP-EQHVDVTGIFARYVDSGISKTVNL------SSSATVDDVRKVYETCYDMGCKgiTIY----RDGSRDNQ-------------------
>UniRef50_B7KJK7(818-1122:1123) Ribonucleoside-diphosphate reductase n=4 Tax=Cyanobacteria RepID=B7KJK7_CYAP7  E=2e-71 s/c=0.90 id=28% cov=39%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CTESFSNVKPGL-------ESHCCNLVSLNLAN-LDNSDLEDTCKIAVRLLDNTIDLTHPPFEAAKNHNNLYRTIGVGCMGLADWLAKRRLSY---EHLTDISHLFEEIGYWCTLSSMELSQERGAYACFPGSDWSQGKLIGSKPVEWFIENAHHPER--WAKLAEDIQLYGIRNSHITAIAPNTSSSLVQGCTASVLPVYSRFFYDKWAKGAVPIAPPFIKESFWFYPEN-KTYDQNKVVKAIAVMQQWIDTGISMELlfNLNQGVYFPEDperfLKAKDIYDTLILAWREGCKAVYYIRTvqKDNFKDS---------DNSCSSCA---
>UniRef50_C1F6S8(51-769:1083) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F6S8_ACIC5  E=1e-112 s/c=0.57 id=22% cov=62%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQCSACFINAVDDSLDSILTLAKTEGMLFKWGSGTGTNLSPIRGSMEQLSG-GGTASGPLSFMRGFDAFAGVIKSGGKtRRAAKMVILNVDHPDIVDFIECKMKeeakawalmregydgssgpdsEAYSSIFFQNANNSVRVNDEFMRAVEKDGEFT-------------------------TRTVKDGAAVK-TYKAREIMHKIAEATWQCGDPGMQYDSTINRWH-TSKNSGRINASNPCSEYMFL------------DNSACNLASFNLLKFmtpagtFDIRAYRHAIDVLITAMEILVDNSGYPTENIARNSHDYRPLGLGYANLGALLMALGLPYDSDAGRDFAATLTAIMCGEAYLQSSRIAEKcpplasatpltasvernGGACPGFyvnrepfldvirmhraEVNKIGKSKTSSEPFKVPELDALITASKECWDQALAHGEKYGYRNSQVTVLAPTGTIGFMMDCdTTGIEPDLALVKYKKLVGGGMIKIVNNtvpaalfklgyknedvdaivsYIDATGTIEGAPGIKPEHlavfdcsfkpakgtrsihylGHIKMMAATQPFLSGAISKTVNM------PHDSNIDDIAEAYLESWRQGLKavAIY----RDGSKGAQ-------------------
>UniRef50_Q77MS1(236-820:822) Ribonucleoside-diphosphate reductase n=9 Tax=Herpesviridae RepID=Q77MS1_GAHVM  E=1e-110 s/c=0.69 id=24% cov=69%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFLALANQLFVPSTPCMLFLGREGTSTASCYLMDPrtnntQDTLKAI---TEDVVPHLLARGGIGISLQHLNGKF-----------GLMHVMKVLDSLVMAANVNESRPTGICVYLEPWHADIMSALNMRgMVAAEESRRCDNVFLALWSCDLLFKRYlrhvngEKNVIWTLFDSRASI----LTKLHSEEFEKEYERLESEGLGV-ASIPIRDMMFAIIKSAASTGSPFILFKDACNRHYITNTQGDAIAGSNLCTEIIQ--------KTDANTNGVCSLASINLARCvrnidgnrqFDFDALRYAVRLATVFVNAIMEGSDVPTEKSHSGRERNRSMGIGVQGFHTAFLSMGLDLCDERARSLNKLIFEFMLLEAMTVSCEFC-ERGlpPFADFSNSYYARGRLHFDGWAN-----VELAAVEEWNMLRDRIVSAGLYNAQFIALMPTAASAQVTEVSEGFSPLFSNMFSKVTSTGELLRPNiQLMEELRTIyldnenqrlatiaalesanwniqtalgnkpechsllkYKTAFD-YDQALLIDLCSDRAPFVDQSQSMTLFITETADGTLLASR--VMNLLLHAYKAGLKTgMYYCKIRKATNAGVFCGDGELTCSSC-------
>UniRef50_Q97K72(5-788:987) Ribonucleotide reductase, vitamin B12-dependent n=2 Tax=Clostridiales RepID=Q97K72_CLOAB  E=1e-103 s/c=0.48 id=22% cov=63%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRTQASACFIISIEDKLlgsHSISEQYVTETKLFKGGSGTGTNFSTIRAKGEKLSG-GGISSGLMSFLKGLDRNAGAIKSGGtTRRAAKMLCLNVDHPEIMDYITWKAKEEDkvkalgkmgydasfegeayETVSGQNANNSVMLSDEFMKKVCNLKN----NPDETIELKGRVDSSVNKVE-----------------KISNLWEAFNKSSWRCADPSPLFSDTLNAWHtcpggedgNFNADYNKINSTNPCGEYAFL------------DDTSCNLASINLYKFydtenktFDLEGYKHVIGLVQLLLEASIHWGQFPTEDVARKTHMFRTTGLGISNLAALLMVMGYPYDSEEGRAISSSLIGVLTGYSYYISSLMAKEVGAFEKYNINKehmlkvlrnsaraagsidtpfekigYKPLVVNHSILEKEDLRYISSELKNSWNSALESGEKYGFRNAQVSVMAPTGTISFAMDCaSTSVEPFFSHVIYKKLSGGGYMTLTNPLiqESLKHLGYSENEIEDitnyilrkkkvktddgteyetildgkiegaphlkkehlaifdtankcgsgnrfisPMGHILMVASIVPLISGSVSKTVNL------PKDASVEDFKNVIINSWKLGVKgiTLY----RDSSKESQ-------------------
>UniRef50_Q8UEM4(46-923:1272) Vitamin B12-dependent ribonucleotide reductase n=163 Tax=root RepID=NRDJ_AGRT5  E=1e-100 s/c=0.42 id=21% cov=65%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPQPHACFIQSVEDDLvneGGIMDLWVREARLFKYGSGTGSNFSYLRGEGEKLSG-GGKSSGLMSFLKIGDRAAGAIKSGGtTRRAAKMVVVDADHPDIEAYIDWKVN---EEQKVAALVTGSKIVakhlKAIMKACVncEADNGDCFDPAKNPALkreiraakkdmvPENYVKRVIQFAEQGYKdiqfktydtdwdseayltvsgqnsnnsvslkddflraVENDGNWnltarkdgkVMKTLKARDLWEKISHAAWASADPGLHFNTTMNDWH-TSPAEGPIRASNPCSEYMFL------------DDTACNLASLNLlqfkdakTKRIDIADYEHAVRLWTVVLEVSVMMAQFPSRQIAERSYEYRTLGLGYANIGGLLMSSGIPYDSDEGRAIAGALTAIMTGVSYATSAEMAGELGPFPSFAPNRDNMLRVIRNHrraahgqsegyeglsvnpvaliHADCTDQDLVAHATAAWDKALELGEKHGYRNAQTTVIAPTGTIGLVMDCdTTGIEPDFALVKFKKLAGGGYFKIINraVPESLRslgysesqiaeiEAYavghgnlnqapainpstlkakgftdekieavnaalKSAFDIKfvfnqwtlgadflkgtlkvsdeqlsdmsfnlldhlgfakkdieaanvhvcgamtlegapflknehlavfdcanpcgkigkrylSVESHIRMMAAAQPFISGAISKTINM------PNDATVEDCGAAYMLSWKLALKanALY----RDGSKLSQ-------------------
>UniRef50_A4L245(22-682:683) Ribonucleotide reductase large subunit n=1 Tax=Gryllus bimaculatus nudivirus RepID=A4L245_9VIRU  E=1e-80 s/c=0.46 id=20% cov=74%
--------------------------------------------------------------------------------------------------------------------------------------------YIFTGAAIQLLQERYLNKG-------ENIQEGFARIAsyFCDNSNVPLWRNIykclsatnilvsSVIARYQDTYSSSYATVAGVTRDEDTTTKGK--ACLLAVMPEKYnEDALRLMWKLFDYLAKGIGIGLCIDNVPKYGSD--GYEYIKGGIHEFLDLLSHVNGV--RITKRESNFAVYISIYRDTLYDVLNIRQRN---KNKLLNVFPAVKIPNMFMKKVRNNEAWYLFDVTESQLLDKT--KNEKEFEELYETFVSEQKYTNM-YESRKIFKDIIKNILMTGSPYIIFIDNVNKFNNI-KHLGKIKTLNLCSEITNY--------CNEDVISTCLLLSVNVANFKHQWDLVSSLENILskefnvnfKDDDFVIEldetsklcwsyckiMGFLATVCLNYflGSSKRREIGVSPLGVYDAIIISK----TDQPLFFCKLISESLYKGCVLASVAWSKKFGiRCKNFENSCFSRGEFQFDLRNLTYKNIS------DWSSLKRDVLLYGMANSLLTCQAPTATTSLLADVTPSVtEPhdccdficrehsFRSLSLSYVMKNFFIKNNVEMINFSKKLFQLKLSKNLYKVSL-------PYIDQSQSVILN--------GNFSSLELMEYLIYAYNNDFKTaLYYINLKSTGTSMLYD-DTKKENEICDSCS---
>UniRef50_B8G0R6(15-306:1153) Ribonucleoside-diphosphate reductase n=5 Tax=Bacteria RepID=B8G0R6_DESHD  E=2e-80 s/c=1.04 id=22% cov=34%
-----------------------------------------------------------------------------------------------------------------------------------------------------ILEKRYL--KQENGEVAESPEDMLYRVASIIAQVEETFGKTkkevkELAKSFYEMMAKLEFMPNSPTLMNAGRDLGQLSACFVLPVEDSMEEIFDAIKSAAIIHKSGGGTGFSFSRLRPKNSTVRSTGGVASGPVSFMKVFNAATEAVKQGGTRRGANMGILRVDHPDIREFITCK----EDNKEITNFNISVGITEEFMKAVQEKRHYNLIDPHTK---------------------EADGQLY-----APEVFQLIVDHAWRNGEPGIIFLDRLNRDNPT-PQLGEIEATNPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3QTY4(57-736:737) Ribonucleotide reductase large subunit n=2 Tax=Oryctes rhinoceros virus RepID=A3QTY4_9VIRU  E=2e-79 s/c=0.44 id=20% cov=73%
------------------------------------------------------------------------------------------------------------------------------------SWLDTDRDFIYSSHGMRLLKNRYLL-------PAEPIQYCMLRIAKlfsrrnssnnssSSDGNSIDDINFQLWRLMYDVLSCG-YMHTSSILADADNADKNIVPgeaCRLLVCNPDYDRAFvNQINEICNLISLGVGVGMSASTVPLHGYAVNG--KIRGGFKSFARKLDSCNYLSIY--ERKPKIAIYIEMHNNTIYEAFELRNPLT---NHLENVFVGIMVPDYFIECYENDEDWYLFPGDAKLDGRTLCEFTGDEYKRMYKRFVEANLYTNK-VSSSALMDDLVTCISETGSPYVVWSDNVNRFSNH-KHLGKIKTLNLCAEIANYAS--------VGKSSSCTLMSVNFAMYREFPDVLDRVYAFVEehsefdagyngFHRAASEFQHATMSKYAYAmgfvatwalnmfmgvTRKQRELGVSPLGAYDMAIMDGV-----DPVKVIAELSEAMYKGCIYSSCKFARMYDVeCAYYKGSPFSEGIPQWLLRDER------KIITTDWTKTCELMRTK-MANSQLTAQAPTATTSMLVGEAESVTIPMSIVMARESENGRNDLICygLLYKLLMEPAEPLHLDNDIDRQLLMYARSAPFIDQSQS-TMF-------SIVLSRQNILNLIMDTYYLKLKTaIYY------------------------------
>UniRef50_Q91ES8(27-604:624) ORF127 RR1 n=2 Tax=Baculoviridae RepID=Q91ES8_GVCP   E=1e-76 s/c=0.50 id=22% cov=62%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVFSKDHNVDAKFEELTRIARVAIKGTGVGIgadslkNKSTTRAPGE-LRNTY------VDFCKSLNHLINL--SVTVRQSRVAVYVSLHNTTAYESLFLRQ---TGNIQTENIFYGIMVPDLFVRKQKEGGVWHFFDNDAQVDGKSLNDCYGEEYERLYEEMVRRG-IQIKSVNVWELWGEIVNCLATNGYPYIVWRDTVNKYNN-QQALGVVKTLNLCAEVCQ----HATDSTVDTNTSLCTLMTLNVAAFcEDYTQHWHLIYDDLRQCqipeqcipplgeNKILDHCFYGgymstfVLNCVLGESKRREIGVSPTGLFDAL---HIMYGAAATYEYAmddysARVAEYIYLGCVVGSVVYNRLYGVeCVNFRASRFSEGVFQFDLRGVTP------SLTLQWACIRPHAMR-GMANSMLTTQAPTATTSQITNVTESVqYPLPGRITTKNSETGRFADL-PFYAHFTNQPPSRHPHVSPLRQIKVYANTAPYVDQSQSTIIYCEPKN--------DEISKVLVYTHKAQLKTgVYYL-----------------------------
>UniRef50_A3JKM6(695-1043:1087) Ribonucleoside reductase n=1 Tax=Marinobacter sp. ELB17 RepID=A3JKM6_9ALTE  E=1e-59 s/c=0.67 id=23% cov=37%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CLLGSVNLTMFVDdpftdkasfnYEKYKKVVGIFTRMLDNVVEINGLPLAQQRHEITYKRRHGMGILGLGSTLAMLRMPYGSEESVVFTEDVVREMAVEGWRQSLALGKEKGAAPimddEFEITPKLLGKCPQLTADgyNLGDKLKGRVLHAKYSRYMQRIaevepelvaqlAEKGGRFTHHTSIAPTGTISLSLanNASNGIEPSFSHHYARNiiregrktkekvdvfsfellayrhlSNPGAMPFSDDADKKLPDYFTTSDDVTPA-QHVDIQAAAQLWIDSSISKTANV------PTDFPYKNFKDIYLYAFDKGLKgcTTF----RFNAEAFQGVLVKESDLENT-------
>UniRef50_Q9XD73(4-358:599) Vitamin B12-dependent ribonucleotide reductase (Fragment) n=15 Tax=Actinomycetales RepID=NRDJ_STRCT  E=3e-58 s/c=0.65 id=21% cov=34%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASLNLMKFlrddtasdgasgaggnmsLDAERFAKVVELVITAMDISICFADFPTEKIGETTRAFRQLGIGYANLGALLMATGHAYDSDGGRALAGAITSLMTGTSYRRSAELAAVVGPYEGYARNaDAHKRVMRQHadantaaQRMDDLDTPVWAAATEAWQDVLRLGEQNRFRNAQASVLAPTGTIGLMMDCdTTGVEPDLALVKFKKLVGGGSMQIVNNtvPKALKRLgyqpeqveavvahiaehgnvidapglkpeHYEVFDCAMgeraisPMGHVRMMAAAQPFLSGAISKTVNM------PESATVEEIEEIYYEGWKLGLK----------------------------------
>UniRef50_O64240(169-692:693) Putative adenosylcobalamin-dependent ribonucleoside-triphosphate reductase n=5 Tax=Siphoviridae RepID=VG50_BPMD2  E=1e-53 s/c=0.41 id=23% cov=52%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDVSRVRAAGRKLKTFGGTASGPVPLAKMLtevseilsrcaregeqyrfedggaltgldameidHAIAQCVVAGGVRRSARMAMMHWADWQVETFTNIKQDSGSHW----TTNISVEVDDAFWSLAKA--PVDPLNPRST--------------------------------KAHRVLKALSEGAVRNGEPGMWDSSLSNVGEPNE-----VVCTNPCGEITLEPWEP------------CNLGHINLAAFVtdagktDYIDLIRAHRLMTRFL---IRATFSAVadPKSREVLDRNRRIGVGHLGVASYLALTGRRYsqapGDKRFTAFLREMAAEVDRAAEEFSHEL------------------RIPVPVKKR--------------------------------TVAPTGTIAKMPGVSEGIHPIFSRYFIRRIRFSVLdndqfltasQYAADGYHVEKDQYDksgntWVVEIPTKDTLVEAVAARfgrdaedivesaneltlhqllafQAlyqtcWADNAVSFTANVDPDAYEGVDV-AADLQR--FSGLIKG-STIFpeesfpqapYERiTKQQYEAAAIKAVADGVDEECANGACPI
>UniRef50_O55716(592-913:959) IIV-6 RIR1 intein n=1 Tax=Invertebrate iridescent virus 6 RepID=RIR1_IIV6  E=2e-51 s/c=0.64 id=26% cov=35%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CSEIILP--------TDSTRTAVCCLSSLNLEYYDEWKDNDLFIKDVMEMLDNAltifIEKAPPTISRAVNSAKKERSIGIGVLGFHSFLQQKNISFESDEAAKLNIDIFTKLR----------------------SK-------IDTFNLVLGSLRGSP---------EDAEGTGRRFCCTMAVAPTATSSIIMGNTSpSVEPFRANAYRQDTLSGSFLNKNRYLsrilsqrlnvkeinevwsnivsnggsvqqlpnnllsEQEKQVFKTAFEI-NQKWVIKHAADRQKYIDQSQSINLFLKP------DIHKRELHSLHLNAWKSGLKTLYYLRSEKIADADKISSNHMINSIN--------
>UniRef50_A7NFN4(29-614:769) Ribonucleoside-triphosphate reductase n=3 Tax=Chloroflexi (class) RepID=A7NFN4_ROSCS  E=7e-45 s/c=0.32 id=16% cov=52%
------IIKRDGRVVPFDVTRIENAMARCFasfgrtpdtpiPELAQRVVNIVAAKSQGKPPTVEGVQDIVEMVLQAAGEFEA---------AKRYILYRAERARERERRP--IPDHVRRAFDEArvyfptpLQQFQFFDKYSRFNYDlgRRETWIetvDRAVDYLHELAGDRLPRETY---ERIRRSILEmraMPSMRLLAMAgpaarrNAVAIYNCSYQPVESIDSFVEALIismagcGVGFSVESRYVENFpRIKRQTGKPPTTFVVEDSAEGWADALRYGLETWFEGGDVHFDLSHLRPAGAPLRTKGGRASGPEPFRAMLDFVRNRIF---ARQGSF---LRP--IDAHDIMCAVGNAAVSGGVRRTAMISLFdYDDDEMRLAKSG--------------------DFERENSQRWNANNSAVWPRGGLTQLEFIRHFMEMVeSQRGEPGIFNREASNLMKPARRKEAEF-GTNPCGEIVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3QY00(831-1025:1966) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Bacteria RepID=B3QY00_CHLT3  E=1e-33 s/c=0.76 id=23% cov=21%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASLNLIHFvnektgdVDTDALRHAARVWTLTLEISVLMAQYPSPKIAQQSYDYRTLGLGFANLGSLLMVSGTPYDSPKALAVAGAISAIMTGEAYATSAEMAADIGAFPKFAHNRDAMlrvvrnhrhaahnapkedyedlSVVPMSLDPAHCPKKLCKVAGETWDRALKLGEKHGFRNAQVSVIAPTG------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B1ZWW1(37-684:842) ATP-cone domain protein n=2 Tax=Opitutaceae RepID=B1ZWW1_OPITP   E=1e-43 s/c=0.28 id=18% cov=70%
----RMVIKRDGSKVRFDQSKVTRALALAFHEVRTDNaPNPYRDHLLACFGLDTETFNEVSRISGAVAQMLelyyrDGKHPSIEQVQDAAEKAIAAAGHWEVARAYMLYrarhaeRRLAHYVDNGMADYIAMAKYARYRPDLGRREIFTEgvervRDMHLTFFADKLerqlssalpaeitdLAGKnaeLLVRSIGGMRLDQIIADAFTQVATkkvlpsmrsmqfggpAILKNHSRIfncsfanvDRIEFFREYFFLLLSGcgvgfsvqkhhiAMLPPLP-------PRGAENDLPVvhFHIEDTIEGWSDALHALIMSFYEGTKIEFDYSRIRPRGSLLKTSGGKAPGHLPLKKALGKVEALLHEAAGR---ALRPIEVY--DLNMFI-AKAVLAGGIRRSAT--ICLFSPDdeEMMNA--KTGNWFDKHPHR--------------------SASNNSAVLSRSDKNIEHFKKLFKAQKEFGEPGFFFNDH--------PDAG----CNPCAEInLLPVVNWELSQDEVAKLFAngykgdlpgttrlsgfqhCNLTTIN----------GQAATTETAFYKACIAATVIGTLQAAYTDMPY----LGpitkLINEHDSL--LGVS------------ICGFMDN--------------PGVLFDQEILTSGAKLCRATNRLVAKLIGIQPA-----------------AKLSTCKPEGTASLILGAASGIHPHHARRYFRRV------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9DWE5(449-1048:1064) PR45 n=1 Tax=Rat cytomegalovirus Maastricht RepID=Q9DWE5_RCMVM   E=1e-39 s/c=0.28 id=21% cov=46%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLYAVNVPQFFWERYVEEgasGRWQVFQKSECKSLCRV---DEKGFRTAYERLELEGNglslSPWWVVRHLDacvalgntavVYPYNLKSAMvgETGRLLLCGPELS---LVCNSFLGVFPENkiDVCLENCLLEGSGADDAAAATEGEVPVLGH---EVFFSFRSLRVLVRDAVvignVLMDAVIRDNVFG---AGDVMCLYRPLQLRVLGFHAVLGRLGLLYTDDASVLLGRRIAEFVHYAAVRASVDLCVHGAePFPKFSRSLFATGRLYPDLFDDPLQETSSLPAGH-WAQLREDVVRYGVRNSAFVCGGLGEESANVAGTTPGMfpraynlslEPSPLLAAPRDRCLGEALRVAEDLrldlpnasdrsllalvgnqrvylpvvnrylaeiprsravlavrmgyaaglyagveeeDEDRASLETGW-MTSQEAVLKMAVDRQPYVDQGQGLPLF---------------------------------------------------------------
>UniRef50_C1FEX6(3-783:841) Ribonucleoside-diphosphate reductase n=4 Tax=Chlorophyta RepID=C1FEX6_9CHLO  E=0 s/c=1.02 id=31% cov=94%
----MYVVKRDGRQEPVHFDKITARINKLAYGLNQefCDPVLVAQKVAVGVYKGVTTSELDELAAETAASMTSK-HPDYAQLAARIAVSNLHKNTLKSFSETMKVMYEHVNKRNGKWSPLLaddVYEIIKENADRFDSEIVYDRDFDYDYFGYKTLERSYLLR--VDGKIVERPQHLLMRVAIGIH------KDVEKAIDTYHMLSERWMTHASPTLFNSGTPRPQLSSCFLIAMkEDSIEGIYDTLKECACISKSAGGIGLSIHDIRATSSYIRGTNGTSNGIIPMLRVFNDTARYVDQgGGKRKGAFAIYLEPWHADIFDWLDLRKNHGKEEARARDLFYGLWTNDLFMKRVEANGEWTLFCPNEAPGLADCW---GEEFEALYEKYEAEGK-GKKTVKAQQLWFAILESQVETGNPYMLFKDACNRKSN-QQNLGTIRSSNLCTEIVEYTSP--------EETAVCNLASIALPRFviennpqsptgrteakklrgsigaanryFDHDKLAEITRKVTRNLNRIIDVNYYPVETARRSNMKHRPIGLGVQGLADVFILLGMPFDSPEAKKLNAEIFETIYFAALTESNDIAKRDGTYESYPGSPVSNGVLQPDMWGLTE---MPGGDRHDWTGLRTKISEHGVRNSLLVAPMPTASTSQILGNNECFEPYTSNIYARRVLSGEFTVVNqhllsdltemglwdpslknelianngsvqslDIPDNLKEIYKTVWEIK-QRILVDMAADRGAFIDQSQSFNVHM-------SDANSGKLTSLHFYAWKKGLKTgMYYLRSRAAADAVKFTVDPN-------------
>UniRef50_Q9ZLF9(2-788:788) Ribonucleoside-diphosphate reductase subunit alpha n=54 Tax=Epsilonproteobacteria RepID=RIR1_HELPJ  E=0 s/c=0.98 id=28% cov=97%
----ITVVKRNGRIEPLDITKIQKYTKDATDNLEGVSQSELEVDARLQFRDKITTEEIQQTLIKTAVDKIDIDTPNWSFVASRLFLYDLYHKVSGFTGYRHLKEYFENAEEKGRILKGFKEKF---DLEFLNSQIKPERDFQFNYLGIKTLYDRYLLKD-ANNHPIELPQHMFMSIAMFLAQNEQELNKI--ALEFYEVLSKFEAMCATPTLANARTTKHQLSSCYIGSTPDNIEGIFDSYKEMALLSKYGGGIGWDFSLVRSIGSYIDGHKNASAGTIPFLKIANDVAIAVDQLGTRKGAIAVYLEIWHIDVMEFIDLRKNSGDERRRAHDLFPALWVCDLFMKRVLEDAMWTLFDPYECKDLTELYGQD---FEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLPFLAFKDNANRCNP-NAHAGIIRSSNLCTEIFQNTAPNHYYmqieytdgaieffeekelvttdsnitkcankltstdilkgkkiyiatkVAKDGQTAVCNLASINLSKINTEEDIKRVVPIMVRLLDNVIDLNFYPNRKVKATNLQNRAIGLGVMGEAQMLAEHQIAWGSKEHLEKIDALMEQISYHAIDTSANLAKEKGVYKDFENSEWSKGIFPIDKANNEALKLTEKGLfnhACDWQGLREKVKANGMRNGYLMAIAPTSSISILVGTTQTIEPIYKKKWFEENLSGLIPVVVPNLNVETWNFYTsAYDIDAKD-LIKAAAVRQKWIDQGQSINVFLR-----IENASGKTLHEIYTLAWKLGLKSTYYLRSESPSIDEKSVLDRSVECFNCQ------
>UniRef50_C7NLI3(33-813:875) Ribonucleoside-diphosphate reductase n=1 Tax=Kytococcus sedentarius DSM 20547 RepID=C7NLI3_KYTSD  E=0 s/c=0.94 id=28% cov=93%
----MRVVKRSGEHEQVDVTKIVAAVERCCDGLPEVDPLRVATKTISGLYDGATTAELDKLAIATAAEMTATE-PQYSRLAGRLLAGVIDKEVRGQ-GIGSFSAAVRTGHEQGLIGDE-TAAFVAEHASRLDDAVYRAQaahaDWRFDYFGLRTVYDRYLLRHPLTRAVVESPQYWLMRVSAGLSHTG------EEAVEFFELLSSLAYLPSSPTLFNSGTRHTQMSSCYLIDsPQDDLDSIYERYHQVAKLSKFAGGIGLAFSRIRSRGALIRGTNGHSNGIVPWLRTLDASVAAVNQGGRRKGAACIYLEPWHPDVEEFLELRDNTGEDARRTHNLNLAHWIPDEFMRRVEADGQWSLIDPDAVPELPDLW---GPAFDAAYRAAEERGDVVR-TVSARYLYGRMMRTLAQTGQGWMTFKDASNRACNQTSDDQTprvaadgtvqpapvVHLSNLCTEIIE--------VTSNDETAVCNLGSVNLAAHlqwsdgttgvrptdpaaratgIDTDRLRSTVRLAVTYLDRVIDINYYPSEQAAASNPRWRPIGLGSMGLQDVFFALRMPFDAPEAKELSTRIAEEIQLSALERSAELAEQFGAHPAFAETRAARGQLQHDLQGVEP------TQTERWAAVRQRIADHGLRNSLMIAIAPTATIASIAGCYECIEPQVSNLFKRETLSGEFMQVNtalvgelkslglwteavreklkadngsvagiaDLPEETRRLFRTAWEL-PQKALIEMAAARQAYVDQSQSLNLFMESPNIG-------KLSSMYLYAWKAGLKTTYYLRSRPATRIQQ-------------------
>UniRef50_O84834(239-1008:1047) Ribonucleoside-diphosphate reductase subunit alpha n=148 Tax=cellular organisms RepID=RIR1_CHLTR  E=0 s/c=0.94 id=30% cov=93%
------VLSKDGSTYTMTHSQLLAHLARACSRFpETTDAALLTDMAFANFYSGIKESEVVLACIMAARANIEKE-PDYAFVAAELLLDVVYKEALGKSKYaedleQAHRDHFKRYIAEGDTYRLNAELKHLFDLDALADAMDLSRDLQFSYMGIQNLYDRYFNHHE--GCRLETPQIFWMRVAMGLALNEQ--DKTSWAITFYNLLSTFRYTPATPTLFNSGMRHSQLSSCYLSTVQDNLVNIYKVIADNAMLSKWAGGIGNDWTAIRATGALIKGTNGRSQGVIPFIKVTNDTAVAVNQGGKRKGAVCVYLEVWHLDYEDFLELRKNTGDERRRAHDVNIASWIPDLFFKRLQQKGTWTLFSPDDVPGLHDAYGEEFERLYEEYERKVDTGEIRlFKKVEAEDLWRKMLSMLFETGHPWMTFKDPSNIRSA-QDHKGVVRCSNLCTEILLNCSET--------ETAVCNLGSINLVQHIvgdglDEEKLSETISIAVRMLDNVIDINFYPTKEAKEANFAHRAIGLGVMGFQDALYKLDISYASQEAVEFADYSSELISYYAIQASCLLAKERGTYSSYKGSKWDRGLLPIDTiqllanYRGEANLQMDTSSRKDWEPIRSLVKEHGMRHCQLMAIAPTATISNIIGVTQSIEPTYKHLFVKSNLSGEFtipnvylieklkklgiwdadmlddlkyfdgslLEIERIPDHLKHIFLTAFEIEP-EWIIECASRRQKWIDMGQSLNLYLAQPDG-------KKLSNMYLTAWKKGLKTTYYLRSSSA------------------------
>UniRef50_C1VDU7(8-775:845) Ribonucleoside-diphosphate reductase n=1 Tax=Halogeometricum borinquense DSM 11551 RepID=C1VDU7_9EURY  E=0 s/c=0.93 id=27% cov=94%
-----------------QTNDVRTILNQARTGYEDVLTDEVmdrlVTETERNLYDGASIDEVYEALEGVTTARIERD-PAYKYVAADIHRRRYFRrvtgeqlsETADDDTATTYRETFAANLERGVDEDLLDERLLdgRFDIDELADALVLERDDKFDYIAMSTLTQRYFIKTEVDGDPLELPQAFWMRVAMGLAIEE--DDPQARALEFYDVLSRLLFTPSTPTLFHSGTTHPQLSSCYLTTVEDDLEHIFDSYKHHAQLSKWSGGLGNDWTNLRAEGALIESTGVESTGTVPFLKISNDVTAAINRSGKRRGAACGYLEAWHMDFPAFLDLRRNTGDERRRTHDMNTAAWVPDLFMERVENDETWTLFSPDEVPELHETYGEEFAELYREYEEKAEAGELRqYETVDAADLWRTMLTRLFETGHPWITFKDPCNVRSP-QDHVGTVHSSNLCTEITLNTS--------AEEHAVCNLGSVNLSNHVadselDREALADTIETATRMLDNVVDLCFYPTDEAEYSNMRHRPVGLGVMGFHDALMQVGTSMASEEAVEAANRWQEFVSYHTILNSSRLAKERGAYETFEGSKWDRGILPHDTVDrleaeRGREIPTDRSETMDWDRVRDHIAEHGMRNSNTMAIAPTATISTINGTTPSIEPIYSNLYVKSNMSGDFTVINEqlvddlkaeglwddemvdqikffdgsiqevsaIPEEMRELYRSAFEIDP-RHQLRLTAHRGQWIDQSISHNVFFPSTDGSLLD-------DVYKTAWRLGVKTTYYLRTLGASQIEKSTLDMA-------------
>UniRef50_C7NVI1(3-769:815) Ribonucleoside-diphosphate reductase n=2 Tax=Halobacteriaceae RepID=C7NVI1_HALUD  E=0 s/c=0.91 id=28% cov=94%
------------HQTPTQTDRIASILDRATDGEPTVtesDRTALRRAIDENCYAGADRAEVYEAILGTLSARIEAK-PAYKRVAARVFRQRYYHEVIGEdltgteldrAYRTIFRENIERGVATDLLDTRLVDRF---DLDALAEYLAPERDEHFEYLAMETLYQRYFLRTN-DGEHLELPQAFWMRVAMGLAVEE--DDPNARAKEFYDVLSKLEFTPSTPTLFHSGTTHPQLSSCYLTTVPDDLEGIFDAYKHHAQLSKWSGGLGNDWTPLRAEGALIESTGVESTGVVPFLRISNDVTAAINRSGKRRGAACAYLAIWHLDFPAFVDLKRATGDERRRTPDMNTAAWIPDLFMERVQAGESWTLFSPDEVGDLHEATGEAFAEKYREYEQAAENGDIEnFETVEAAELWRTLLTRLFETGHPWVTFKDPCNIGSP-QDHEGTIRSSNLCTEITLNTS--------TDEHAVCNLGSVNFATHMrdgelDRDYLEDTVETAMRMLDNVVDLCFYPTEEAEDSNMRHRPVGLGTMGFHEALMEIGVPMNSNEAVEKANRWQEFVAYHAIRTSSELAGERGAYPSFEGSKWDRDILPQDTVDlleeeRGREIPTERTETLEWDAVRKSIAEHGMRNSNTMAIAPTATVSTINGTTASIEPQYSNLYVKSNMSGDFTIVNDhlvadlrerdlwddemrdrikyhdgsiqeieaIPEDLRELYRGAFEIDP-RHQLRLTAHRQTWIDQSVSHNVFFPSTDGTLLD-------DIYTTAWELGLKTTYYLRTLGASQVEKSTLDLS-------------
>UniRef50_B0RGP9(2-778:834) Ribonucleoside-diphosphate reductase n=15 Tax=Bacteria RepID=B0RGP9_CLAMS  E=0 s/c=0.89 id=26% cov=95%
---SITVVKRDGSKEPYDANRINLAIEDATQGLDENIgwVTQIASELEITLFDGITTQQLDEAVIQVALQNV-KDDPAFDTVAARLLLKTIYKRVLGDYSSPEELkrlhaEHFARNIQRGVDEMLLDSRLVQlFDLERLAQALEPAHDELLKYIGVVTLNNRYGIKGR-NGDALEVPQYFWMRIAMGLTLNEQ--NPTETAIAFYEKMSKLEYLAAGSTLVNAGTIYPQLANCFVMEMQDDIEHIAKTTRDVMWLTKGTGGIGLSVSKLRAQGSPIRSNNTTSTGPIPFMHTIDSVLRAVSRGGKKFGALCFYMENWHLDFPEFLDLRQNSGDPYRRTRTANTAVWISDEFMKRVQNDEDWYLFDPLEVSDLNELYGKAFSERYAFYVGEAEAGRIRMfKRINAREQFKSILISLQTTSHPWLTWKDTINNR-ALNNNTGTIHLSNLCTEITLP--------QDEDNVSVCNLASINLSQHFadgkvDFAKIEQSARLAVRQLDNLIDITRSSVKEADFSNQQNRAVGLGVMGFTDIVEKLGFSYESEESYDLIDEIMEHVSYAAIDESADLAKERGAYPNFEGSRWSEGLVPLDsialmEADRGVPVKVNRTTRLDWDALRAKV-KGGMRNATLMAIAPTASIGLVAGTTPGLDPQFSQIFSRSTSSGKFLEVNRnlvkdlqelgiwetvrenilrsqgdiqniaaIPDHVKATYRTSFQLSPY-AFLEVAARAQKWIDQAISRNMYLETRDLG-------DMMDIYFAGWERGVKTTYYLHMKPRHTAEQST-----------------
>UniRef50_C4V8X4(60-800:800) Ribonucleoside-diphosphate reductase n=1 Tax=Nosema ceranae BRL01 RepID=C4V8X4_NOSCE  E=0 s/c=0.91 id=26% cov=89%
------------------------------------------LKIESGLCDDITVEEFISFAAETADSMTTK-HYDYGRFSAKILMEYLKENTLDSFFAKVDYIY-----KNGDFYSEKFYNIVLDNKKFLDELVDYSKDDSWTYFAILTLKRAYLLT--LDGQTIERPQDMLLRVAVQLHG-----DNLENVKETYELLSNNMYTHGSPTIFNSGSKKSQLASCFLLtPIEETVEGLFETVKRCVQISKSGGGVALDLHDMAAKGTSIRKTGGISKGIIPYIQVLNWSLKYIGQAGSRRsGCPAIYLEPWHKDIFDFLDLRKSIGKDELRARDVFTGMWINDLFMKRVEANEDWSLFCPKSVPGLSNAY---GKEFEDMYLEYEK--KVDCVVVPAQKVWKAIIESQIETGTPYMLYKDTINNLSN-QKNIGTIRCSNLCTEIVQYTSP--------DEVAVCNLASICLPKFvingeFDFNLFKSVVKIVTKNANIVIDCNFYPLKEAEKSNKKHRPIGLGVQGLADVFLMLRLPYESEGARKLNKEIFETLYFGALESSCEEAEKYGPYESYNGSPISKGIFHWEMAN------SSTTGRWNWEELRKKILKYGVRNSLLIAPMPTAGTSQIFNNNEAFEPFTSNIYTRRTACGEFQMVNrylmndliklnmwspeiknyiveqegsiqnisGIPEEIKELYKTVWEIKMK-CVIDLAADRQAFVDQTQSLNLFVAKPTYPI-------LSSMHFYGWKRGLKTgMYYLRTRPITSAIKFTVDLDMlkkvekneatneelkeneinKSDICESCSC--
>UniRef50_B7SW23(170-902:904) Ribonucleoside-diphosphate reductase n=1 Tax=Spodoptera litura nucleopolyhedrovirus II RepID=B7SW23_9ABAC  E=0 s/c=0.92 id=27% cov=87%
---------------------------------------------------GVSFEQMKLYCADVAASM-TYIHYDYALLAGRILVEDLHNKVCPCFVEVTNYLAQNNVV------SHEFNNLVVKHGALLNREIKHNRDYDYKYFGFKTLTNGYLLK--VNDVIAERPQHMLMRVALAIHG-----DDVMSAIETYQLMSLGTFTHASPTLFAAGTCRPQMCSCFLQCIkEDSIDGIYKTLHESALISNLGGGLGLSVQSVSAQ----YNGTTKSGGLVSMLRVFNNMVRHVDQGGKRKGALAAYVEPWHPEIYDVLNLRRNMGSEDAKARDLMLGLWIPDLFMERVKENKEWSLFCPKKYPGLLDEY---GSSFEILYEKYEKN-KLYERQVKARDLFRFIVETNVETGGPYMLYKDPCNKFSN-QKNLGIIKCSNLCAEIVQY--------CDKDETAVCNLASIAVNKCvnvktktFDYVLLNRLTKIVVRNLNKIIDSNHYPTAGAANSNKKHRPVGVGIQGLADAFVLLDIPYDSEEARSVNYMIAETIYFSALEASCELAKIDGPYESYENSPLFRGTMHYDNYN-----IYPTDHLWNWSKLREKIQRHGVRNSLLVAYMPTATTAQILGNNESFEPFTSNVYLRRVLAGEFQVVNqylikalvdlniytpelrnkilaengsvqnidEIPQHVKDLFKTAWEIKSK-CMIDMAADRAPFIDQSQSLNLFVAEP-------TYSVMSSIHFYTWQKQLKTgMYYLRTKPAAQATQFTVDaeaaascgkkRKMDDDGTEECmSC--
>UniRef50_B7XJ88(31-778:778) Ribonucleoside-diphosphate reductase n=2 Tax=Enterocytozoon bieneusi H348 RepID=B7XJ88_ENTBH  E=0 s/c=0.89 id=27% cov=88%
----------------------------------------------------MTPTEMTKYCSEIAATMITI-HPSYNKLAAIILIKHLHENTFNTFSDKMMYIQQEKNI----FDDHIMELII-NNMNVYNSIVKYERDYNFDYFALISLQKSYQIQ--VNNTVIERPQDIYMRVAIELHG-----DDFNNVQKTYDLLSQQYYTHATPTLYNSCFKKNQLASCFLLGMkSDTIAGIFDTIKEAAIYSKLSGGVGLHISNLRCDKSQLVTTGGYSKGIIPIVKLINDSMKYINQGGARRCATCAfYLEPWHKDILKFLDLRKNTGIEEERARDSFTALWINDLFMERVEKNEMWSLFDPNIAKGLQDVW---GDQFNKLYAYYEET--IERTTIPAQKLWKEIICSQIETGTPYMCYKDTCNRYSNQN-NIGTIKSSNLCAEIIQYS--------DSDITAVCNLASICLPKyvkinsttsnyYFDFQELYTVVKIVTYNMNKMIDKSAFPTEESKKGNSLFRPIGIGVQGLADVFFLMGYSFESKEARDLNKMIFETLYFGALEASCELAQKHGPYSYYQGSMYSQGIFHFEKFCEGRINVNEILSgMWNWEELRIKMKTYGVRNSLTLALMPTASTSQICGNSECIEPIQSNIFTRRTFAGEFQIVNKYlmkdliklglwnneikqliieyegsiqkipiiPQHVKDLYKTVWELKMK-SVLDMAIDRQAFVDQSQSLNLFVKEPTYGI-------LSSMHFYGWKNKLKTgMYYLRTCPLAKAIKFTVDKelilktlssfkdsendkklNKENDYCEGCSC--
>UniRef50_C3N5F1(11-783:838) Ribonucleoside-diphosphate reductase n=12 Tax=Sulfolobaceae RepID=C3N5F1_SULIA  E=1e-180 s/c=0.82 id=24% cov=87%
------VIKRDGRVDEFKLEKILSKLSS----VPDEVTDGIVNDVQANVKDNaIDTRAIADIVERNLIEN-SLKYPFLMELAKRYVLARIYNHVFGK----------------GKWKDF------------------NEKDLLLSYNALKVLEARYLLKDPNTLRYIETPQMLFRRVARFLASVERKYGKSEaevkqLEEKFYEMISSLKFVPNSPTLMNSETRLGILSACFVIPVKDAMttpegDGIYDALRATALVHQQGGGTGFDFSELRPKGDVVASTAGVASGPVSFMKVFDASTDVIKQGGKRRGANMGVMHAWHADIEDFIRAKTGQLKD-VQLQNFNISVGAYDYFMEAVVKGESVPLINPRKTKiagrdheyyiTKARGYMNEEWIQEVIISELEEKGGVvsldeskvitvdealiiaskegaVVRYVNAKSLFDEIVKGAWDSGDPGLLFIDTINRRHPV-WYLGKINATNPCGEEPLLPWE------------SCNLGSINLEKFiierngkveIDWDGLAEIISYGVRFLDNVIDANRYPLKQIEDATKRTRKVGLGVMGLARMFIKLGIAYDSVDAIYLSYQLAKFIFYHAYKASIEVAKEKGPFPTYDSKLYRdiwesaldfNSLLQIAEVADKPSDYVKKLTgvvdKLDFDLLKDERLKYGLRNSTIVSIAPTGTISIIAGTSSSIEPLFALAFVRNVAVGKFIEIDPLfleylrkyelddpeviqkiaesgiigdnvfmPRSLRKLFRTAHEVPPIY-HVLHQAAWQQWNDSGTSKTINLRSEEPP------ETVEKVYLLAWKLGIKgiTVY-------------------------------
>UniRef50_C7DGU7(4-700:762) Ribonucleoside-diphosphate reductase n=1 Tax=Candidatus Micrarchaeum acidiphilum ARMAN-2 RepID=C7DGU7_9EURY  E=1e-178 s/c=0.90 id=24% cov=82%
-----VVIKRDDSKVDFDRTKIENAVFKAYKSVYDSNV----KEAELRKRAENSTTDIVKEIEATG------------------------KKEIRVEEIQDIVEKVLMLKDQTVAKSYILYRHKKAEIRAFRASLGiPDDGLKLPINTLIVLASRYLLKGP-DGKIAESPKQLFTRVSHYIAAAEKKFGKSDdetnaLEMEFYDAITNFKFMPNSPTLMNAGTKLGQLSACFVLPVGDSIVEIFDAVKYAAIIHQSGGGTGFSFSRLRPTNDMVKSTGGVASGPVSFMKVFDIATEQVKQGGKRRGANMGILRVDHPSILDFIVAKENEGT----LRNFNISVAITDEFMKALEANRDYSLVNP-------------------------RNGKVV-GKLNARAVWNLIITMAWKTGDPGLVFLDRINsSYSNPVPTLGPVESTNPCGEQPLYPY------------DSCNLGSINMAKMlkkndgqydIDWDELKRITRMGVRFLDNVIESNTYPLKEIEDVTKKIRRIGLGIMGWADMLIKLGIRYDSNEALMLAEKVMSFITENARKMSEELAEERGPFPAFKDSIWYKLGY------------------------------KPLRNSTVTTIAPTGTISIIAgGASQGIEPIFSVVYMRNVHESlgsnlievnnefeamaiennfysdelmkklagrvSIQDVEEIPQEIRRLFVTAYDIAP-EWHVRMQAAFQKYVDNAVSKTINF------PSWATPQDIEKAYVLAYKLGCKgiTVY----RDSSKSVQ-------------------
>UniRef50_C5A3W2(5-787:911) Ribonucleoside-diphosphate reductase n=2 Tax=Thermococcus RepID=C5A3W2_THEGJ  E=1e-177 s/c=0.80 id=23% cov=86%
------VMKRDGRIVPFDRERIRWAIKRAMLEVGVHDDKLLNRVVRRV--------------VRRINELYDGQVPHIENIQDIVELELMRAGLFEVAKAYILYRKKK-------------AEIREEKKKILNKDRLDEIDKRFSLNALRVLASRYLIRNE-KGEIIESPRELFERVAtlavipdllydervydkngkheqdlsrvkyylehfeefdgrysigrfklnkyhferlvnlyrelaekgrmkvsidefLGMLENGAFDDYESEVEEYFRLMTGQVFMPNTPALINSGRPLGMLSACFVVPIEDDMESIMKAAHDVAMIQKSGGGTGLNFSKLRPEGDFVGSTAGAASGPVSFMHLIDAVSDVIKQGGVRRGANMGILEVWHPDIEKFIHAKEKN-IGTNVLSNFNISVGIWEDFWEALRDGKRYPLVNPRTGEKV--------------------------KEIDPKSLFEELAFMAWSKADPGVIFFDVINRRNVLEPaKGGPIRATNPCGEEPLY------------EYESCNLASINLAKFvkyddegkpyFDWDEYAYVIQKVAKYLDNAIDVNRFPLPEIDYNTKLTRRIGVGMMGLADALFKLGIPYNSEEGFAFMRKATEYLTFYAYKYSVEAAKKRGTFPLYEKSRYKDGELPVEGF------YHREIWNLPWDELVEEIKKHGVRNGMVTTCPPTGSVSMIADTSSGIEPIFALVYKKSVTVGEFYYVDPvfeaelkkrglwsdeilkkisdnygsvqgleeIPEDMQRVFVTSMDVHWLD-HILAQANIQLWLTDSASKTINM------PNDATVEDVKAAYLLAYKLGCKgiTVY----RDGSLSVQ-------------------
>UniRef50_C0QY27(8-772:773) Ribonucleoside-diphosphate reductase n=2 Tax=Brachyspira RepID=C0QY27_BRAHW  E=1e-171 s/c=0.79 id=32% cov=96%
--KKHIIIKRDGREEPFNEEKLRKVIDWATEGKEA-FTNQLLEGLNIKINDKMKIEVLYDELINTAVNMISPLYPMYDTIAEKLYLMKIYKETCGLkkiGSYPHIKNFLKKGIKYKIYDKDIIQLFTDKELDKINSMIDPNRDLLFTYKGLAIFYKKYC--KNIGNKKLELPQITYMVAAMFSFYDDyykgenkdkleiSKSERLKYIKRTYDMLSRHEVTFATPRIANSMTIKAQLASCILNTPADDTWSLNQTDGNMALYSKFSGGIAYDASYIRASGSTIQTNRGRSDGPIPFIKRVEQTISSFNQGGVRKGACVVTFPWWHLDVLDLIMLKDAGGTEDTRARKLVYSIRISNIFRERVNKDGYVTLFDPKETPLLNEEY---GEKFNVAYIYYESKSSIRKKKIKAKDLLFQILKVRQETGNLYLTFVDNINEQNMVNRFVG---ASNLCQEIVIPSYPSKLIKEkyvinedgeyeiiqrkKSGEIGICNLVSVNLMSWVNFspEKKKSFCYTLLRGCDNIIDTQFYPVKEGEIANKKNRPIGIGVINYANLLASNKIKYTDKEALEFTNKVFDDLYYHIYEASNILARERGPYKTFNESKWKEGLTPFHISLLNNNKKNNLNVSVDkekWDKLAENIKNNGVRFSFHGAIAPTATSGKSVSATESIEPIVDLFFIEEGIQ-TLPSLVPNIKKNREYYERCWNIPAK-TIIELAAVRQRYIDQSQSLNLYYVKPD------SAKELWDDIQYAMDLGLKTLYYMKTpKSNFEL----------EEVCESC----
>UniRef50_B7R7T8(11-564:724) Ribonucleoside-diphosphate reductase n=2 Tax=Thermoanaerobacteraceae RepID=B7R7T8_9THEO  E=1e-164 s/c=1.05 id=24% cov=70%
----------------------------------------------------------------------------------------------------------------------------------------------------KVFLDRYALKDREGKPVEKKPEEMFKRVAKAIATNEKEE------EMFYKVMSEWKFIPGGRILAGAGTGREvTYFNCFVIPVEandpkkgnDSRAAIMDTIAKMLEINSRGGGVGINWSTLRPRGAYVKGVGGTSSGAVSWMLAANEVATQVEQGGSRRAALMFMLWDWHPDIEEFIKVKK----DLTKMQQANLSVAVSDAFMEAVAQDKMWKLEFPDTShPNYDAEWKGDLNEWKAKGY-----PTVVYKEIPARELWNKIVTAAWESAEPGVVFLERYNKLSNT-YYITKIISTNPCGELGLEPY------------GVCNLGAINLVAFVengriNFEELEETVKIAVRFLDNVLDLGAYVLPQNKEMAQKLRRVGLGLMGLADALILMNLRYGSEESLKATEEIVKRIRDAAYRASVELAKEKGPFPEFVADKYLKGQFIQRL----------------PKDIRDEIAKYGIRNATILTQAPTGTTSILAGVSSGIEPNFAKEYVRKDRTGT--HTVKHWLADYPAFVSAHEVTPEE-HVKMQAVLQKYIDSSISKTINL------PRTATVDDIDNIYRLAYELGCKgiTVY-------------------------------
>UniRef50_Q3ZZA0(20-590:761) Ribonucleoside-diphosphate reductase n=27 Tax=cellular organisms RepID=Q3ZZA0_DEHSC  E=1e-163 s/c=1.01 id=23% cov=67%
------------------------------------------------------------------------------------------------------------------------------------------------------LERRYLKKDK-QGKTTETVEDMFRRVARTIAMGEliynPKADVRSREDEFFNLMTRLEFLPNSPTLMNAGRELGQLSACFVLPVDDSIESIFDAVKHTAMIHKSGGGTGFSFSRLRPEQDRVGTTGGVASGPVSFMRAFDVATDVIKQGGTRRGANMAILSIDHPDIMKFVHAKDKAGV----LTNFNLSVAITDKFMQAVKDGVDYDLLNPH-------------------------NGEVV-SSLNASEVFNKIVHMAWKTGDPGIVFIDRINAYNPT-PQLGRIESTNPCGEQPLLPYE------------SCNLGSINLSRMvtvsggqntVDYKKLSRVIKSAVRFLDNVIDVNKFPLPQIDEMTKKSRKIGLGVMGFADMLLELGVPYNSENSIKLAEEIMCFVNDEAHKFSSELAVERGVFPAYRGSIYEKSGRP-------------------------------MRNASCTTIAPTGTLSIIAGCSSGIEPHFALCFTRNILDGtKMIEVNPYferaakeggyyseelikslaegahldevdvPQDAKDLFVTAHQIVP-EWHVRIQAAFQKCTDNAVSKTVNF------SRDAGECDVAEVYKMAHARNLKgiTIY----RDGSREDQ-------------------
>UniRef50_B0KCF5(1-563:770) Ribonucleoside-diphosphate reductase n=24 Tax=Bacteria RepID=B0KCF5_THEP3  E=1e-162 s/c=1.02 id=25% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------------------KVLEKRYLAKDE-NGKPIETVEEMFERVAKTIAEVDLIYDQNADVEavkkRFYDMMVDLDFLPNSPTLMNAGRPLGQLSACFVLPVGDSMEEIFDAVKYAAIIHKSGGGTGFSFSRLRPKGATVRSTGGVASGPVSFMKVFNAATEAVKQGGTRRGANMGILRVDHPDILEFIQCKK----DNNEITNFNISVAITEEFMKAVEEDREYDLIDPHTGK--------------------------VVNRLRAREVFDLIVEMAWRNGEPGIVFLDRINEKNPT-PEVGEIESTNPCGEQPLLPYE------------SCNLGSINLENMlkkvegryvIDYDKLRETVYDAVHFLDNVIDANKYPLPQIEEMTKGTRKIGLGVMGFANMLLRLGIPYDSDEAVKLGEELMEFIDETSKEASIKLAEQRGTFGFYDKSIYKKMGIKIRNATTTTIAPTGTI-------------------------------SIIAGTSSGIEPVFAIAMTRNVMDntelvevnpvfkevaiergfyseelmreiarrGSLKDIKGIPEDVKRVFVIAHDI-DHEWHVKMQAAFQKHVDNAVSKTVNFR------NEATVEDVRRTYLLAYKLGCKgvTIY----RDGSRESQ-------------------
>UniRef50_A8LK99(16-579:765) Ribonucleoside-diphosphate reductase n=25 Tax=Bacteria RepID=A8LK99_DINSH  E=1e-156 s/c=0.98 id=24% cov=68%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------WRRIARALASVE--SDPAAWEPKFYAALEDFKFLPAGRITAGAGTERSvTLFNCFVMgTVPDDMGGIFEGLKEAALTMQQGGGIGYDFSTIRPKGAAVKGVAADASGPLSFMDVWDAMCRTIMSAGSRRGAMMATMRCDHPDIEAFIAAKSDPA----RLRMFNVSVLVTDAFMEAVKADGSWDLVF-------------DGK---------------VYHTVEARDLWNKIMKATFEYAEPGVIFIDRINAANNL-SYCETIAATNPCGEQPLPPY------------GACLLGSINLSRLIsdpfgegaalDEAALEELVATAVRMMDNVVDASRFPLEAQAAEARAKRRIGLGVTGLADALLMVGLRYGSEAAARQTERWLHRIARAAYLASVQLATEKGAFPLFEADAYLQ----------------SGTMQTMDADVRAAIAEHGIRNALLTSIAPTGTISLYAGNvSSGIEPVFAYSYTRKVlqKDGSRTeeEVVDYAvqlwrekfgdADLPDHFVNAQTLAPLD-HVRMQAAAQKWVDSSISKTINC------PEDISFAEFKDVYMAAWDQGCKgcTTY--RPNAVTGSVLSVSDSATKDSEAEKGEVK-
>UniRef50_C5WF13(49-726:728) Ribonucleoside-diphosphate reductase n=8 Tax=Bacteria RepID=C5WF13_STRDG  E=1e-149 s/c=0.78 id=24% cov=85%
---------------------------------------------------------------------------------------------------PSLEEKLAYLIKEGYYEQAIFDLYPDDVIKEAFQYAYQQDYRFLNLMGAMKFYQSYALKTLDGKYYLETVEDRVVMNALFLA-----NGDQTLLFNLIKDMLHRRFQPATPTFLNAGkKRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREIGAPIKEIENQATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIKSLALGLVIPDITFQLAKENKEMALFSPYDIKRVYGKDMSDIS-ITEEYNKLLANPAIKKTYISARKLFQLIAELHFESGYPYLLFDDTVNQRNPHAQK-GRIVMSNLCSEIAQVSTESTYNDDlsfkDIGEDICCNLGSINIAeAMTDAKHFSQLITTSIRALDQVSRASDLScAPSIEKGNAANHAVGLGAMNLHGFLATNHLYYDSEEAVDFTDLFFHTMAYHAFKASCQLAKEKGAFADFERSTYADGSYFKQYVIEDAKPKTKRiaallksygfqlPTVADWKALVRDIQTYGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRK-EGNLGRIYVPAYQINQENYayyeRGAYEMGP-EPIIKIVAAAQKHVDQAISLTLFMTDQ------ATTRDLNRSYIQAFKLKCASIYYVRVRQEvlAGSEQYDEDSQLDSvdkngltdtiNECQSC----
>UniRef50_A2DI13(20-612:614) Ribonucleoside-diphosphate reductase n=1 Tax=Trichomonas vaginalis RepID=A2DI13_TRIVA  E=1e-148 s/c=0.89 id=22% cov=69%
----------------------------------------------------------------------------------------------------------------------------------------------FTSNAIKVMKARYLVHNEE-GKVYETPEQMFTRVAKALASVET--DKEKWTKKFEKVMMNFEFIPAGRTLANAGAKTDLVSNCVVLHMEDSLDSIFQTLQDAALLQQAGSGIGFPFHKLRPAGYKCKRTLGSSSGPLSFLRIYAEAFRIIQQHG-RHGANMAIMRVDHPDIIEFIHAKEQPGTYE----NFNFSVAFTDEFMERVIKNDP----SPWMCK-------WNGEKMAPRYITRDAAGRVENIqplTISAPELMNEIIHLAWTNGEPGCVFIDTVNKANPL-PGLGPIECCNPCGEQFLHSGD------------ACNLGAINLEKFVvdgkiDFKHLEEVTRTAIRMLDNVVSLTKFPVQRVTDMFTNNRRIGLGIMGLADLLFLMKLPYDSEEGRACAEEVMKCVQDSAIDESKRLGLEKGSFPNFEKSVWADKVPA-------------------------------MRNTSLTNVAPTGSTSMLLDVSSGVEPYFALAYRRgnclagpmkpfvnkhlqkaledcgcftdKIMDkiletGTLANVTEVPEQLRRVFVTSLDIKAED-HIAMQARVQKHCCNAISKTINFRR------EATEDDVRAGFIEGWKNGCKglTVYRNGSRDA------------------------
>UniRef50_Q2LW62(6-537:551) Ribonucleoside-diphosphate reductase n=1 Tax=Syntrophus aciditrophicus SB RepID=Q2LW62_SYNAS  E=1e-145 s/c=0.97 id=22% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------------------LRERYLIRDEA-GTLLETPEELFRRVACSVSQGEnndPEGRSAEMEEAFYEMMTSLEFLPNSPTLMNAGRPLGQLAACFVLPVEDSLDSIFDSVKLTAKIHQTGGGTGFSFSRLRPKNDVVKSTMGVASGPVSFIRVFNCATEAIKQGGTRRGANMGILRIDHPDIMEFVAIKRDPAE----LTNFNLSVAITDEFMRSYEENRDVALINPRT--------------------------KKAAGKVNARELLRFIAEAAWASGEPGVIFLDAINRANPT-PHVGEIEATNPCGEQPLLPYE------------SCCLGSINLSRIVrnggiDWQRLQKLTHLGVRFLDDVVEVSTYPSEEIRAMTSGNRKIGLGVMGFAHLLIRLGIPYDSPDAERTGGEIIRLIERESKIASNRLAEKRGPFPNFKGSVWDRKNLLQRNATTTTIAPTGTL-------------------------------SILAGTSSGVEPIYDIRYKRILPGGIEVEVEdplwrkakdrPDADELrRRLFRKAYEVSP-FAHLNIQRTFQSSVDNAVSKTVNL------PETATADDILDIYVAAYRMGLKGTTVFRNKS-------------------------
>UniRef50_C1DWR9(643-1163:1222) Ribonucleoside-diphosphate reductase n=3 Tax=Hydrogenothermaceae RepID=C1DWR9_SULAA  E=1e-134 s/c=0.93 id=29% cov=60%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CYVNVIDDSLESIMDKAKETAFLAKYAGGVGTDVTRIRATGSKIHSLNAKSSGIIPFIKIFDTIVNAIQQGGRRRSSQVMYLQPWHLDVEAFLDLRETTGNPYFRTPSLNTALWMPDELMRRIKEGEPIYLFDPAECPKLVTAW---GEEFKKEYESCiekaEKGELKLWKKIDSRDFYKKYLFKLAKTGHPWLTFKDRHNEKNPCPQYS-VINSSNLCTEISIPNSP--------ESTAVCTLASVNLARHvkedksdFDWDKLKDTLETMVVALDNILDKNFYPSEESRKNTMDLRPIGIGVMGFHEALIKLGIPYDSDKAVETARKIAKFMREVTYAKSEELAKERGAFPHYYEANYN---YPPR------------------------------RNAVLLAVAPTASISIIAGTSSSIDNYFSNIFSRDTLSGKFIVINkPLMKELeekglwseelaekikahqgsiqyieeldgkidKSLYKTAYEVSPYRQ-IDIAAAFQEYIDQAVSKSLYIEEDLR-------DKMEDIYMYAWEKGLKSTYY------------------------------
>UniRef50_Q18BC3(3-648:729) Putative ribonucleotide-diphosphate reductase n=6 Tax=Clostridium difficile RepID=Q18BC3_CLOD6  E=1e-130 s/c=0.73 id=22% cov=78%
-----YIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISRKIandYNSMekclSVEEIQDIVEV-------------------LLMESNRKDIAKHY---ILYRERRSEIRTKAW-----------EFDELQKSI---------------WKNKY----RHNG---ESFDEWIKRISNNSSRISK-------------LIRQKRFLFAGRILANRGLQKEgkkvTYSNCYVIEPPkDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTGAVSFMELYSMTTGLIGQRG-RRGALMISMDVNHPEIEDFIDIKT----DLEKVTKANISVRVTDEFMQAVREKKLYNCTF-----------------------EVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIKTYNfMSEDKNFCFSGVNPCAEEPLPSG------------GSCLLGSINLSEFiiqpfgehatFDINKLKSCVREAVVALNDVLDegLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDESLELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDT---------------KEMVKKYGLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESlhdedvyyKVYTPIVKEYmdkkgitdeECLPDFFVTAMNIGYEER-INMQKVWQKYIDASISSTINI------PFETTVEDVFNIYIKAWEAGLK----------------------------------
>UniRef50_Q6MNP6(55-717:764) Vitamin B12-dependent ribonucleotide reductase n=1 Tax=Bdellovibrio bacteriovorus RepID=NRDJ_BDEBA  E=1e-127 s/c=0.69 id=22% cov=62%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPQCSACFIQSVDDSIESIFDLAKTEAKLFKYGSGTGSNFSKIRSKYEAT-GSGGKSSGLISFLEVLDKGAGAIKSGGtTRRAAKMVVVDIDHPEVLDFIDWKMREEQkahlliaaglsadfegEAYRTvsgQNANNSVRVSDAFMKAVEQERPWKLKARLTGKVL--------------------------REIPAGEVWNRITRAAWMCADPGIQFHDTINKWHTC-PETDIIHSSNPCSEYMFL------------DDSACNLASINLVKFlndtgdFDFESFIHTARTLFVAQEILVDYSSYPTQRVAQNSHDYRPLGLGFANLGSLLMRKGVAYDSDEGRAWAGALTSLMSGVAYLTSSEMARAKGPFAGYrKNSKSMLKVMKMHERAlnqvawKMLPAGIDKAVRNLWKGVLYNGEKYGYRNAQATVIAPTGTIGLLMDCdTTGIEPDFSLIKFKKLVGGGEIQIVNqsvdaalaslqyfederqailkyveennsvvgapqmHPEDLP-VFDTATAMPGQrvlspESHVKMMAAVQPFISGAISKTVNM------PSTATEEDISRIYFLAWKLGVKavAVY----RDGSKQSQ-------------------
>UniRef50_O69981(120-718:967) Vitamin B12-dependent ribonucleotide reductase n=38 Tax=Actinomycetales RepID=NRDJ_STRCO  E=1e-122 s/c=0.74 id=22% cov=63%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSFNSPVWFNVGTPQPqQVSACFILSVDDSMESILDWYKEEGMIFKGGSGAGLNLSRIRSSKELL-SSGGNASGPVSFMRGADASAGTIKSGGaTRRAAKMVILDVDHPDIEDFIQTKVKEEEKIRALRdagfdmdlggdditsvqyqNANNSVRVNDTFMKAVQDGGKFGLTSRMTGE--------------------------VIEEVDAKALFRKMAEAAWACADPGIQYDDTINAWHTC-PESGRINGSNPCSEYMHL------------DNTSCNLASLNLMKFlkddgkgnqsFDAERFSKVVELVITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYDSDGGRALAGAITSLMTGTSYRRSAELAAIVGPYDGYARNakphlrvmKQHSDENAKAVRMDDLDTPIWAAATEAWQDVLRLGEKNGFRNSQASVIAPTGTIGLAMSCdTTGLEPDLALVKFKKLVGGGSMQIVNgtVPQALRRLgyqeeqieaivahiaengnvidapglkpeHYEVFDCAMGErsisamGHVRMMAAIQPWISGALSKTVNL------PESATVEDVEEVYFEAWKMGVK----------------------------------
>UniRef50_Q7UI46(10-773:1040) Vitamin B12-dependent ribonucleotide reductase n=3 Tax=Planctomycetaceae RepID=NRDJ_RHOBA  E=1e-119 s/c=0.56 id=20% cov=64%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPQGSACFIQSVDDNMEDIMRLACSEAMLFKFGSGTGTDLSTIRSQREKLSG-GGTPSGPLSFMRVYDSIAGVVKSGGKtRRAAKMQSLKVWHPDILEFIECKwaeekkahaliregydsnfNGEAYASVCFQNANLSVRLTDDYMEAVRKNEN----------------------FQTRW--ITDKPTTEPPSYVAKELLNKMAECAWHCGDPGVQYDTTINKWHTC-PNSGAINASNPCSEYMFL------------DDTACNLASINLMKFvqqdgsFDHERFRAACRTFFIAQEILVDHASYPTEPIARNSHKFRPLGLGYSNLGSVIMTAGLPYDSDAARGMCGSLTALLHGEANRTSAELASVVGTFDGYVENEAPMLRVmqmhrdACDQINDDGPAELKEAARELWDGVLEIGEKYGFRNAQATVLAPTGTISFMMDCdTTGIEPDIALVKYKQLAGGGMLKIVNqtvklGLKTLGYDADTIDEIlkyvdandtiegapglqdehlavfdcafkpangvrsIGWRAHITMMAAAQPFLSGAISKTVNM------PTDVTPQDIADAYFWGWELGLKaiAIY----RDGSKQSQPLNTKSDE-----------
>UniRef50_C6LFM8(41-569:757) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=4 Tax=Bacteria RepID=C6LFM8_9FIRM  E=1e-118 s/c=0.81 id=24% cov=59%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSNCYVITPPkDEIEDIFECAKKLARTYSYGGGCGIDISGLAPRGARIHNAAKETSGAVSFMELYSMVTALIGQNG-RRGALMISIDSSHPDVEEFINLKT----DLEKVTKANISVRIHEDFMKAVKENGEYLLSFTREV-----------------------TGERIEKTVQAKELFHKIALTNWDYAEPGALFWDRITGWNLLSNTKEFSYAgVNPCAEEPLPAG------------GSCLLGSINLSEFvqypfteaatFDMEGFRKCVQASVRALNEVLEegLPLHPLQEQRESVAKWRQIGLGIMGLADALLKLGLTYGEQDAVAMCDKIGFAMADAAIATSAELAKEQGAFPACNAEEIMETPY---------------FLANTSEKTRELVRKYGLRNSQLLTIAPTGTLSTMLGISGGIEPVYANSYQRKTESlhgtdvyyKVYTKIVDEYmkqhgiteeNALPGYFVTAM-MLDYHQRIDMQSIWQTHIDASISSTVNV------PNSFTVEETESLYLYAWERGLKgiTIY-------------------------------
>UniRef50_B9LSK3(26-790:1056) Ribonucleoside-diphosphate reductase n=9 Tax=root RepID=B9LSK3_HALLT  E=1e-114 s/c=0.54 id=22% cov=74%
-----------------------------------------------------------------------------------------------------------------------------------------------------ILPARYLRKN-ADGEPIENPEGLFDRVARNVALAEAVFEAEKqgvevtvtpdqlkpdhprrdelaadvfgtgttatddvettltahnvnkfaystvvpelpegvrehveaTADRFRDGMESLSFMPNSPTLMNAGDELQQLSACFVDSPADDITDIHQTAKEAAEVFQSGGGMGYAFWKLRPYGDAVGSTGGIASGPITFMRTFDQMCETIAQGGARRGAQMGVMRVSHPDVIQFIHSKNkdvslahslrlNDPDDfthnsfadaleearelidedgkvpehlrnavEGHLSNFNISVGVTDDFMEALYNDEEFTFTNPRtEEPHIATPETKEIYDMFGLGEHVEVGEVL---SIPADELWDDMIEGAHENGEPGVIYLERVNKEHSFDTKEhpdHRILATNPCGEQPL------------EEYEACNLGHINLSTlaaqdapdwrvwsdehadeydteeaamsafleeAIDFEEFDERIDYGTRFLENVVTMSDFPVEKIEQKVRDMRKIGLGVMGLAQLYIQLGIQYGTEPGNEVARQLMTHINHASKQTSHELATERGTFNDWEESKYANPTEYRDWFEHYTGLDADE-----WED------GFPIRNHNTTTIAPTGTTSMIGNTTGGCEPIYNVAYYKNVSDdvqgdemlvefddyflrtleendvdvdavkqeaqeqmatNEFDGVDGletVPDAIGELFVVTGDLSGK-QHASVQCACQEGVDSAISKTCNF------PNDATAEEMEEVYRYIYDHGGKgvTVY----RDGTRSKQVLTTRA-------------
>UniRef50_D1C7D7(135-867:1139) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Sphaerobacter thermophilus DSM 20745 RepID=D1C7D7_SPHTD  E=1e-113 s/c=0.56 id=22% cov=63%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFIQSVEDDLvnpGGIFDLVTREARVFKYGSGSGTNFSKIRAEGEPLSG-GGTSSGLMSFLKIFDRAAGAIKSGGtTRRAAKMVVVDVDHPDIEAFINWKAEEEKKVAALiaagysadfngeayatvsgQNSNNSVRVTDEFIRAVLTDGEWHL-------------------------RWRTDGRIAK-TVRARDLWHQIAQAAWQCADPGVQFDTTINAWHTC-PASGRINASNPCSEYMFL------------DDTACNLASLNLMKFydaerrtFDIERFRHAVRLWTIVLEISVLMAQFPSEAIARKSYEFRTLGLGYANLGSMLMTMGLPYDSDRARGIAAAVTAIMTGEAYAASAEMASVLGPFPAFAENREHMlrvirnhrraaynahpgeyeglSVAPVGLDPATCPEDLVQAAREAWDRALAMGEQYGYRNAQTTLLAPTGTIGLLMDCdTTGVEPDFALVKFKKLAGGGYFKIANqsiapalrtlgyteeqiedilryvlgtlsldnaphinraslmekgltseevdrleqalpsvfeltyaftpwtlgeealrrlgftpeqwqrpgfnllrelgftpqqiaeandvicgmqtieGAPHLKDEHLPVFDCANKcgkhgrrfihhMGHIRMMAAVQPFLSGAISKTINM------PNEVTVEDIEEAYMASWRLGLKAMalY----RDGSKLSQPLSSASKQD----------
>UniRef50_Q6VMN2(76-796:796) Ribonucleoside-diphosphate reductase n=10 Tax=Tortoise herpesvirus RepID=Q6VMN2_9HERP  E=1e-112 s/c=0.57 id=27% cov=70%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFNLLSHNIIIPPTPAMLFMGRKNRSLASCYLLDPPQktTLEAMSAVAQDIIPILNHRGGIGINVNDYNQT-----PREGRKLGFLGLAKLIDTCVLLSNSDSERPTGVCMFMEPWNADVESFLGIKGLTTLEHHlRCDNIFNALWIPDLFMKRYMADPNttWSLFD-DRCNHLAKLY---GKEFEDEYHRLETAGMAVRQ-MPIKELLFKIIRSAIMTGSPFIMFKDSCNRHYYMDTQGQAIRGSNLCTEIIHHTEP--------DSDGVCNLMNVNLPAFltlsfnketyclsddtlwqehnkfctpgghryFNFEKLTEAVTAATIFINVMIDRSVHPTTKTQNGAKNFRSMGIGFQGLNTLCWILGETLVTPKARKLGKTICEAMYLSAAEASNELCQ-LGlsPFKRFSESRYARGIMHFDAW----DNVGSLTFQDRWSALRPKIIKYGLYNSQFIALMPTVSSSQITESSEAFYPVFTNLYSKLSVNGETVKPNvmllrdlgsvfkgkdytdaleklerhkwvvgeafPDLptDHAIRKYLTAFE-YDQNTLLELTADRAPFVDHSQSNTLYFLEGKTP---ISAKYIMNHLVTAYKLGLKTgMYYCRIKKATDASIFMCAGQEICSTCQ------
>UniRef50_A5FCJ4(30-565:565) Ribonucleoside-diphosphate reductase, alpha chain n=1 Tax=Flavobacterium johnsoniae UW101 RepID=A5FCJ4_FLAJ1  E=1e-111 s/c=0.76 id=27% cov=60%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVEMIERGWMSISSPVWANMGTERGLPISCFNVHVPDKIEGITHKLGEVIMQTKIGGGTSGYFGELRERGSAV-TDNGKSSGAVSFMKLFDTAMDTISQGGVRRGAFAAYLDIDHPDIEEFLKIK----SIGNPIQNLFTGICVPDYWMQEMIDGDA-----------------------------------------DKRQIWAKVLESRQQKGLPYIFFSDNVNKNKPQvyKDQNLRINASNLCSEIMLPSTH--------DESFICCLSSMNLELYEEWKD-TEAVKLAIFFLDAVlqefIEKTEgnYYLSAANKFAKRHRALGLGVLGWHSYLQKNMIPFEGMEAKMKTTEIFKHISDKADKASQELARIYGEPELLKG--------------------------------------YGRRNTTTMAIAPTTSSSAILGqTSPGIEPFSSNYYkaglskgnfMRKNKylkklleekgldneevwrgimlnGGSVQHMSQLTQQEKDVFKTFKEISQLE-IVQQAGIRQKFVDQGQSLNLNI------PAELAIKDVNRLMIEAWQQGVKSLYYQRSQSVSKE---LVTSLVSCSSCES-----
>UniRef50_B9L1R5(126-865:1122) B12-dependent ribonucleoside diphosphate reductase n=2 Tax=Bacteria RepID=B9L1R5_THERP  E=1e-110 s/c=0.54 id=22% cov=64%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFIQSVEDDLvnpGGIFDLVLREARVFKYGAGSGTNFSKIRAEGEPLSG-GGTSSGLMSFLKVFDRAAGAIKSGGtTRRAAKMVVVDIDHPDIEKFIRWKAEEEKKVAALvaagysadfngeayatvsgQNSNNSVRVPDEFIRAVLEDRDWHL-------------------------RWRTDGRIAK-TVRARELWQMIAEAAWQCADPGIQYDTTINDWHTC-PASGRINASNPCSEYMFL------------DDTACNLASLNLLKFydaksgrFDIAAFRHAVRLWTIVLEITVLMAQYPSREIAWNSYRFRTLGLGYANLGSLLMTMGLPYDSDRARAVAAAITAIMTGEAYATSAEMAAILGPFPAFPENREHMLRVIRNHRRAAYDAHPEEyeglhiapqgldathcppelvaAAREAWDRALELGERFGYRNAQATLLAPTGTIGLLMDCdTTGIEPDFALVKFKKLAGGGYFKIVnrsvapalerlgytpeqiqdiltyvlgtlrldgaphinretlrargltedelqrieaalpsvfelrhafsphvigeaalrrlgfspeqwsqPGFDLLAALGFTAEEIEEandvicgrqtvegaphlapehlpvfdcankcgkhgtrfihYMGHIRMMAAVQPFLSGAISKTINM------PHEVTVEDVANAYFEGWRLGLKalAIY----RDGSKLSQPLSTRSSEKEKSERAS---
>UniRef50_Q76Z42(1-440:473) NrdA-A aerobic NDP reductase large subunit n=1 Tax=Aeromonas phage Aeh1 RepID=Q76Z42_9CAUD  E=1e-104 s/c=0.87 id=54% cov=58%
----MLVRKSSGITENFEPKKLLKILGFATAG-TRIDPNEILNGIMPSITDGMSTKNIQKLAIKFAADRISIEQSDYQYVAARLQMYAIRKDVYNQFDPIHLKRHTLDLVQDGIYDKDLAIKWTDDEFNELNAYIKHDRDFDLAYAGVMQFKEKYLAKDRSTDQIYETPQILYMLVAMCLHQDE-KTDRIAKVKNFYDVTSLGKLSLPTPILAGVRTPTRQFSSCVKIESGDELDSINATASSIVDYISKRAGIGINGGAIRAEGSRIRSGEVRHTGIIPFWKYFQTAVKSCSQGGVRGGAATLYYPMWHLEVEKILVLKNNKGVEENRIRQLDYGIQINKLFFERLKNDDYITLFSPDvQNGELYDLFYKDPVKFKELYEMLENEPWCRKKRIKASELFNLFAQERTGTGRIYPMFVDNVNSATPYK---EPIRMGNLCIEIALPTVP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2UNR7(63-932:1180) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Verrucomicrobiales RepID=B2UNR7_AKKM8  E=5e-85 s/c=0.37 id=23% cov=64%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPQCSACFLTEVGDSMEDILDHLTTEGRIFASGSGVGINLSTLRSSKEPISG-KGRSSGPISFDRGWDRMAGAIKSGGKtRRAARMVLMFSDHPDIFEFINTKNRQEDIAKvilREHNVHVELkqiaetkLVAGTPAEKAAARVILSLplatrnsFDPHMDALLYGETLSHqnanhsvslkGDFWQALanngntYTRWVTNPAHIEQTFRAQELLEAMAQSIWDNGEPGVHNNDVINLWNPVKS-IGTITTSNPCSEYVFL------------NNTSCNLSSFNAYRFlikgedgkpvFDADALTHAARLAMVCADLNVERGGFPIEEIAEGTYKYRTTGIGFANVGGSLMALGVPYDSDEGRWIASQLCSALTAACWTASAEMGAELGSYVEYPASKkdllavlrlhnaaqklasalpsqkdsktlddlieniianaggilpeaqgltasyalhaYLKSFKAPTMMNRERIAPAAKLAEAASDMWAKVIKATAHRNAFVSVMAPTGTISAPLGCydegTTSIEPDYTLVKWKQLAGGGSLKMFNrlaleglrslgYPEDFvneaalevagldglisafqgnMDYVVnqlivdpcndqagpvrlawrrllsgtesrseiqekvayisnpanmavlTADELAvvngaahiesipwlnkkdlpvfdcaatngngiraiSPAGHVLMLGALQPFISGACSKTVNM------PVSASVQDIYDSLIMSHELGVK----------------------------------
>UniRef50_C4XRN9(594-935:1096) Ribonucleoside-diphosphate reductase n=2 Tax=Desulfovibrio RepID=C4XRN9_DESMR  E=4e-69 s/c=0.77 id=30% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLGSINLSVFYdpsapdgiDWAGLAETVHLAVRFLDNVIDASRYPLDQITEMVRANRKIGLGVMGFADLLYLLRIPYDSTEALTLAEKLMETVQAEARSASKTLAAERGAFPAYPESIYGKRNL------------------------------GPYRNATTTTIAPTGTLSIIAGCSSGIEPLFALSFARHVMDGEkLVEANPhfvtalreagahsdalmeevtrkgsiahiglLPEALREVFVTAMDIEPV-WHLKMQAAFQKYTDNAVSKTVNL------PNSATKEEIREIYWLAYELGCKgvTVY----RDGCKSNQVLCT---------------
>UniRef50_B8GMT3(19-325:1137) Ribonucleoside-diphosphate reductase n=3 Tax=Thioalkalivibrio RepID=B8GMT3_THISH  E=3e-68 s/c=0.85 id=18% cov=37%
--------------------------------------------------------------------------------------------------------------------------------------------------------RKYRLRDATGRPLEDTPAETLARVARALADVEAtPALREHWRERFLWAL-NHGALPAGRILANAGARDHKrgtsTINCTVSgTIHDTLDEILGKLREAGLTLQSGAGIGYEFSTLRPKGAWVAGAGARSSGPLSFMDVYDQMCRTIASAGDRRGAQMATFHIGHPDVLEFIEAKREPG----RLRQFNLSLLVPDAFMAALDAGADWPLAFPlspaeqaRTGADLQDPKQVVWRHWpETEGYITDGHGRVacrVQQWIPAAALWEQVMRATYDHAEPGVIFIDRVNAENN-NGFCESIRAANPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7LZ05(47-352:1331) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7LZ05_ACIFD  E=2e-54 s/c=0.71 id=19% cov=25%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QASACFILSVDDTMESILNWYHEEGIIFKGGSGAGVNLSTIRSSVEPLAG-GGTASGPVSFMRGADASAGTIKSGGKtRRAAKMVILNVDHPDVEEFVWTKAIEERKARVLaeagfdmgvdgkdafsiqyQNANNSVRVTDEFMQAVVEDREWEL-------------------------RAVTTGEVTK-TVRARDLFHQIAEAAWECADPGLQFDTTINRWHTT-PNAGRINGSNPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9RRW1(79-554:1418) Ribonucleoside-diphosphate reductase n=1 Tax=Deinococcus radiodurans RepID=Q9RRW1_DEIRA  E=2e-53 s/c=0.45 id=20% cov=34%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFWRIADWVAGAEAPEARQGWAQQYYDLMAEKKFCPGGRVLAGAGTQHGNVLNCFVQGatehdpssfegvmevakklalvtkvgggngvnldvyrpraqssrsdngvrgwvymsaehadvqdfieglmrpptqpdgekqpvsvrnwtrvvygqaispelvasarangvqivrtlpegvtaVADDMGGIIDAARQVAEIAKLNIEPRIDLSAMRPEGAPIKGSGGTSSGPVSFlMEIFDNfiewanrgaedsgpintlryvyapVLRVVRQGGTRRGAGMATISIGHPDVLDFLTAKDlDREAAEGDISTFNISILVDTKFWDTLQADGVWT-IDAQDVPGKYFPVPQEGEYagtFPELPTRAEDGAKgvpVYGSGIPARWLWDQIAQHAWSTGEPGLIFNDRVNEYSALK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9DC34(167-676:677) Gp50 n=2 Tax=root RepID=C9DC34_9CAUD   E=5e-55 s/c=0.43 id=24% cov=51%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDVSRVRPFGAKLKTFGGRASGPLPLARMLIDVCEVlseiatvggslngiaameidhaiaqcVVAGGVRRSARMSMMHWQDPQIEEFVRCKQETGKHW----TTNISVVVDDLFWTA--------LNMPNQVS--------------------------IMVRDQAHKALTWITDGMVANGEPG--FWD-----SSLSSQGEPneVVCTNPCGEITL------------QEWEPCNLGHINLAAFvkdngkVDTIDLIRSHRLMARFL---IRATFSPVgdPKSREVLDRNRRIGVGHLGVASYLAMTGRRYSkaplDKHFRKTLRELAKEVEQSAQQFSHEL------------------RIPVPVKTR--------------------------------TVAPTGTIAKMPGVSEGIHPIFAKYFNRRirfskgdaeleklidqgydfepcqyaqntvvvtipTKDTLVQEVVDRFGRDAEEIVESAEDLTLNQLLAFQAMYQMlWADNAVSFTANVDPDRYKPHVVgeQLRTFGGLLKGA------TIFpessmpqapYERiTKKQYKAATTKAVADSVDEECASGACPI
>UniRef50_Q2PDF6(148-649:729) Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase n=1 Tax=Euglena gracilis RepID=RTPR_EUGGR  E=1e-29 s/c=0.27 id=18% cov=45%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DYSKIREMGTKLKTFGGTSSGPGPLINL-------------------------HKSIRKILVGEKGKPISVTCITDIMnlIGVCTVAGNIRRSAEIA----FGEADCKEFLDLKSYETNPHRVEYGWASNNSIFAKVGMD----YSDACERVRTNGEPGFAWLSNMQAFSRMNGKPDyrdqRVLGGNPCLEQSL------------ESMELCCLVETFPDKHETLEDFKRTLYSALLYAKTVTLLPLH-WRESNEIMLRNRRIGCSVSGIAQFITNRGLH----ELKTWLEEGYDILHQYDCQIS------------------------------------------EWLCIRQSIK--------LTSVKPSGTISLVAGATPGVHYPESCYYTRRlrmardspllerlIKAGyhvepccvapDVTAIVEFPVAAGNSIRTTRDITMWEQ-LSLAAFMQRyWADNQVSATITFDPE-----------------------------------------------------------
>UniRef50_P23921(1-755:792) Ribonucleoside-diphosphate reductase large subunit n=248 Tax=root RepID=RIR1_HUMAN  E=0 s/c=1.05 id=30% cov=93%
----MHVIKRDGRQERVMFDKITSRIQKLCYGLNMdfVDPAQITMKVIQGLYSGVTTVEL-DTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKstlDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLK--INGKVAERPQHMLMRVSVGIH-----KEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMkDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGnKRPGAFAIYLEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVW---GEEFEKLYASYEKQGR-VRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSN-QQNLGTIKCSNLCTEIVEYTS--------KDEVAVCNLASLALNMYvtsehtYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDL------WDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPhllkdlterglwheemknqiiacngsiqsipeIPDDLKQLYKTVWEIS-QKTVLKMAAERGAFIDQSQSLNIHIAEPNYG-------KLTSMHFYGWKQGLKTgMYYLRTRPAANPIQFTL----------------
>UniRef50_Q8JKL8(3-753:939) Ribonucleoside-diphosphate reductase n=1 Tax=Heliothis zea virus 1 RepID=Q8JKL8_9VIRU  E=0 s/c=0.98 id=28% cov=93%
-RNPRMIVKRNGSVERFDPSKLYARIERCMTMSEPrlttafINIAGIVADVEKGLYDRVSTLELDTLLSETCASM-STAHPDHSILAARIAMQALHKRTRSKFSETIRDLYEANIVPQYYFD------LVQEHADTLDSAIVDDRDFQsLTYFAYKTLERTYLIK-LADGKICERVQHMYMRTALGIHG-----RDIESVIETYNLLSNRYYVHSTPTLCHAATNRSNYASCYLLELkEDSIGGVMDTLKDAATISKHCGGVGLHVHKLRCKNSTIHSTNGNASGLVPMLRMYNAMSRYVTQGGnKRPGAIAVYLEPWHADVFDFIEMRKNSGFEEARARDLFYALWVPDLFMKRVNDGGYWSLMCPDSSPGLSDCW---GEEFEAKYTAYEQEGRYVRR-VDARELWKAIVTAQVETGTPYILYKDTVNRNSN-QRHLGTIKGSNLCTEIVEYASP--------DETAVCVLASVNLPKFvegkvFNLNLLAKTVRLVTRNLNKIIDNALYPIPSAAKSNFKHRPIGIGVQGYADALAMMGIAY--EDSMQLNRDIFETIYHAALTESCQLARVHGVYESYHGSPTSRGELHFDRYSV-------HSQKCDWSSLRKDIARYGLRNSLLVAPMPTATTSQVFGNAESFEPFTSNMYQRRTQSGEFqltnvhlvrdlerlnlwnddmaqlimynngsiQNITIIPEELRRIYKTVWEIPTK-TLIDMAADRGAYIDQSQSFNLYVAEP-------TYSRMTSIHFYAWNKGLKTgMYYLRTKSATNAIPFTVDVN-------------
>UniRef50_C5DY80(16-796:875) Ribonucleoside-diphosphate reductase n=1 Tax=Zygosaccharomyces rouxii RepID=C5DY80_ZYGRO  E=0 s/c=0.93 id=28% cov=94%
---------------EYNPPLMRQKLRELSFGLNLDylDFDKIVQKISSGVPDDVEGWQVIRHAAETVASLTSI-HPDHSILAARLEIDELHKSLRgitftenlkqlrsstrvtseGDNRVPSKRQKVMRAPKKGVISEEFLQMALKYE-KKLNDAIVHERDFNFTYFGWKTLCQSYLIKKNAD-QIHETPQFLFMRVALAIHG---PFEDIDSVIETYELMSRKYFIHASPTLFNAGTVNQYLSSCFLVGMkEDSIEGIFKTLEDTALISKASGGIGIHVSNIRASGAHVSGSNGTSNGIVPMLRVFNNTARYVDQGGnKRPGAYCIYLEPWHSDVFDFLQLRKNHGKDELRARDLFFALWIPDLFMKRVQCNGEWSLFSPDEAPGLSDVY---GKEFEELYEQYEATA-LPMKRVKAQKLWSEILQAQVETGGPFMLYKDSCNLKSN-QKNLGTIKSSNLCCEIVEYSS--------KDETAVCNLASVALPTFvvqvtnkgsiFDFVKLHAVVKTITRNLDRVIDVCKYPIPQAQYSNLRNRPEAIGVQGLADVFLMLRIPYESQEARILNTQIFETIYHAAVETSIELAEEYGAYETFQGSPASQGLLQFDLWGLNEDNY--DFLYRDWGELKHRIQNGrGLRNSLLLGPMPTASTSQILGYTESFEPMTSNVYARRVLSGEFINVNQYmvdhfcqlgiwneklknriiadngsvqniqglPDWIKKIYRTVWEI-PQRPLIDMARDRSPFIDQSQSLNLFMKTP-------TMGKLTSMHFHAWRHGLKTgMYYLRTQAASAAIQFT----VNDENTLTGSVEL
>UniRef50_B0R7R5(16-774:804) Ribonucleoside-diphosphate reductase n=2 Tax=Halobacterium salinarum RepID=B0R7R5_HALS3  E=0 s/c=0.93 id=28% cov=91%
--------------------------------------DRILTEATRNAYDDATTDERYDALLGALTGRIDR-HPAYKTVAGRVLRERLERRLVDDYDPATRdaatRQAFRDGIQRGLDADLLDERMGDYDLNRLADAITPARDDRLDYMAMDTLRQRYFLR-EPDADPFELPQPFWMRVAMGVALREDPADREEYAIEFYDALSTLRFVHSTPTLFHAGTTHAQLSSCYLTTVPDDLDGIFDAYKEHAKLSKWSGGLGNDWTPLRAAGSLIESTGVESTGTVPFLKISNDVTAAINRSGKRRGAAAAYLACWHLDFPAFCDLRRNTGDERRRTHDMNTAAWIPDLFMERVRADKQWTLFSPKETGDLYELYGSDFAERYREYEAMADDGDIqRFERVDATDLWRTMLTRLFETGHPWLTFKDPCNVRSP-QDHAGTVRSSNLCTEITLNTS--------EEETAVCNLGSVNLARHlddgdIDREQLSETVETAMRMLDNVVDLNFYPTENAERSNMRHRPVGLGVMGFHDALQQMRVPMASDDALDRADALQEYVAYHAIGASADLAAERGTYESYEGSKWDRDVFPQDTVDrleseRGREIPVPREERLDWSDVRQRVATHGMRNSNTMAVAPTATISTIAGTTPSIEPVYSNLYVKSNMSGDFTVVNDrlvadleerdlwteelrdkltyhdgsvqeldaVPEDVQELYRTAFEIDP-RHQLRLAARRGVWIDQSQSVNVFFPETDG-------SKLSEVYQTAWELGLKTTYYLRTLGASQIEKTTLDMDEYDD---------
>UniRef50_Q7T6Y8(74-831:881) Ribonucleoside-diphosphate reductase large subunit n=1 Tax=Acanthamoeba polyphaga mimivirus RepID=RIR1_MIMIV  E=0 s/c=0.91 id=26% cov=93%
---------HNGSIQVITSEIIRTYVEKIFEkmEVTHLDIDKMTKNIFPKLKSINTIKDIDNQIISTASEMVT-DHYDYPKIAVWILMTNLHDNTSDDFLETAekLYNNKSESNKNAPIISENIYNFIKKHIKEINRVIRYDRDYNLTIFGFRTLEKSYLKR--INKKIVERPQHLFMRVAITLH---YRKNDLDRIFETYKYLSKGYFTHATPTLFNAGTTHEQLSSCFLLGIGDSLEEISECWKECALISKHAGGIGIHMTNIRVEGAYIASTQGEAGG-LRVLTIFNDISRYANQGGKRPGSFAIFIEPWHGDIFFFLDLKKNTGAETERARDLFLGLMINDIFMERVYKDDVWSLMCPSQCPNLLNKY---GDEFTKEYLKYESEGIYLKQ-IRAIDLWFKIMESQIETGVPYVMFKDAINDKSN-QINIGVVNGSNLCCEIVE--------VSDKNNFSVCNLSSICLPRFvkiidevptFNYQKLFKISRILTRNLNNIIDINFYPLDKTRITNLRDRPIGIGVQGLADVFAMFKTPFDSEIARDLNRKIFETIYYGALTESNKLAREFGTYQTYQGSPISQGKFQFDLWNFDKSQLSG---MWDWELLRQEILNHGVRNSLVTTCMPTASTSQIMGWNECIEPYTENIYSRSTMAGEYFVINkhlikdlielgvwnsemvdlikyykgsvanipNIPDNIKAIYRTVWEI-PQKSIIEMAADRAPFVDQTQSMNLYIDKP-------SFARLNSCLFYAWRKGLKTgMYYLRSKPASSANQFGID---------------
>UniRef50_B9L2K7(21-733:770) Ribonucleoside-diphosphate reductase n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9L2K7_THERP  E=0 s/c=0.94 id=30% cov=86%
-----------------------------------------------------------------------PDRPEAEREAAALLLEKIAREA-DDGTPLPYPEHFRRFVERGIARGALDPRLRTFQLDVLARALDPARDALLGYAALATLADRYLVRDPETRQLLERPQALFMRVAMGLALVEPPETRTSWALRWYDLMSSLRYLPSTPTLFNAGTPHHQLASCYLAEVEDSLESILGSAYEFGMLAKYAGGIGTAVTRIRATGAPVRGINGTSGGLIPFLHLYDALIASISQGGRRRGTMCVYLEPWHLEVEAFLDLRRNAGDPYRRTHQLNTALWIPDEFLRRVETDDLWYLFDPIVAPELPDLVGAAFSErYRELCRQAEAGmlPRRAWRRLPARELWLAILASLMETGHPWLTFKDAGNLRSQLRG-IGVIHSSNLCTEIFLPTSR--------DEVAVCNLGSVNLARHctptgeLDWEQLAATVRLAMRALDNVIDANLYPSERAARANQLNRPVGLGLMGFAELLARRAVSYAEPAAADLADQIAEFLSYHAISASCALAEERGAFPNFAFSRWAAGVLPIDTldelaADRGLPVEVDRTRRLDWEPLRQRVRR-GMRNGAVMAVAPTATIALLAGTTPSLDPYYANVFSRQTLSGKFLEVNPILvEELRRrglweqllpglvaargdlravpgcppdlvaRFPTAYQVPA-ESYIEVAARVQKWVDMGVSRNLYHAADRPG-------QMSAVYLAAWRKGLKSTYYCFVRPRMEIEQST-----------------
>UniRef50_A8MCH3(9-844:877) Ribonucleoside-diphosphate reductase n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8MCH3_CALMQ  E=1e-179 s/c=0.76 id=24% cov=93%
----ITVIKRNGLREEFNPVKLLNSLKLA----GAPNPERILEEVTSQIkgKGEVTSSEISDSVQLMMLNLISEDFK-WHDAARNYLLFSIYKQAWGKEVVKSinsgsltlseayrrgLRDWFNQGLNQGLWSLDA-AKFYEKHLDELMNKLDPSRDLLLTYNGVRTLMSRYLMK-RLDGSFFETPQYMWMRIAMGVAYSEVKYGNdpIKWVEKFYDLVSQLKFLPNSPTMFNALTKLGELSACFVIPVDDCLSkdsnrdnpncffGIMDAAKLAALLFQAGAGVGYQFGELRPEGDVVKSTSGVASGPLSFMRLFDTLVDVIKQGGKRRGAQMGMLFWWHPDIEKFITSKTGRLKD-VQLQNFNISVTIDDYFMTKALRGEDVYLLNPRECTCLYQTW---GQEFIKCYEECVSKVKAglvkVWRRVNAGELWSKIVESAWDSGDPGLWNRDVANMKieyvnDVVSEKYRVINGTNPCGEVALYP------------FESCNLGSINLTKYingnsIDWVSLANDIMLAVRFLDDVIDSNQHPHEYLDRANKASRRIGLGINGWADVLVSLDIPYDSPKAIALADVVMGFVARVAVRASVELAKEKGPFPLWPSSKWRSGFLPWRVHDERVSKMLEvkgvssdveeyleilklgygelgglpnkaeeylAKLRATDDELIKDASTVGVRNGALISIAPEGSRSLIAGVNSSIEPIFAIAYVRNLSIGKLIEYNytalrklkdsnaldnettskvlesgmlPSNHVMHPVLKTANEIHW-RWHVFMQVTFAKWSDSGVSKTINM------PSNATKEDVNGAYRLAWALGAfgITVY----RDKSKAVQ-------------------
>UniRef50_B5IVI5(5-941:1042) Ribonucleoside-diphosphate reductase n=1 Tax=Thermococcus barophilus MP RepID=B5IVI5_9EURY  E=1e-164 s/c=0.62 id=23% cov=87%
------VMKRDGRIVPFDEGRIRWAIQRAMWEVGVRDEKLL--------------DKVVKDVVGRINELYDGKIPHIENIQDIVELELMRNGLFDVAKAYILYRKKK-------------AEIREEKKKILNKDKLDEIDKRFSINALRVLASRYLMKNEE-GKIIESPRELFERVAIlavipdllyddrvfskegGFAQDLKRvdyyrehldefdkklsigrfklnkyhferflslyqelaekgqmkvsideivkmledgafDKYEKEIEEYFRLMTNQIFMPNTPALINAGRPLGMLSACFVVPIEDDMESIMKAAHDVAMIQKMGGGTGVNFSKLRPEGDLVGTTTGAASGPVSFMHLIDAVSDVIKQGGVRRGANMGILEVWHPDIEKFIHAKEKN-IGTNVLSNFNISVGIWEDFWEALKEGRKYPLINPRTGKKV--------------------------REVDPKALFEELAYMAWAKADPGVVFFDVINRRNVLEKAKGqKIRATNPCvvgdtriltekGEieieklfelakeanidrlevldegalgeraekyayllpfkvIASNGKPVEAYVWKVGfkpsikivledgreltgdeehkvkvgdnyielknikvgdcievfkegckkvvevasvgnqlvytltmkevheyvansiisrncgeeplyEYESCNLASINLAKFvkyddegkpyFDWDEYAYVIQKVAKYLDNSIDVNKFPLPEIDYNTKLTRRIGVGMMGLADALFKLGIPYNSKEGFDFMRKATEYLTFYAYKYSVEAAKKRGTFPLYDKSDYPEGKLPVEGF------YHREIWNLPWDELAEEIKKYGVRNAMVTTCPPTGSVSMIADTSSGIEPIFALVYKKSVTVGEFYYVDPvfeaelkkrglysdellakisnnygsvqgleeIPEDMQRVFVTAMDVHWLD-HILAQASIQLWLTDSASKTINM------PNDATVEDVKAAYLLAYKLGCKgvTVY----RDGSLSVQ-------------------
>UniRef50_A1KG47(8-639:710) Ribonucleoside-diphosphate reductase n=20 Tax=Mycobacterium RepID=A1KG47_MYCBP  E=1e-157 s/c=0.88 id=24% cov=75%
------VRRRDGTLVPFDIARIEAAVTRAAREVACDDPDMpgtVAKAVADALGRGIAPVEDIQDCVEARLGEAGLDD------VARVYIIYRQRRA---------------------------------ELRTAKALLGVRDELKLSLAAVTVLRERYLLHDE-QGRPAESTGELMDRSARCVAAAEDQYEPgssRRWAERFATLLRNLEFLPNSPTLMNSGTDLGLLAGCFVLPIEDSLQSIFATLGQAAELQRAGGGTGYAFSHLRPAGDRVASTGGTASGPVSFLRLYDSAAGVVSMGGRRRGACMAVLDVSHPDICDFVTAKAESPSE---LPHFNLSVGVTDAFLRAVERNGLHRLVNPRTGKIVA--------------------------RMPAAELFDAICKAAHAGGDPGLVFLDTINRANPV-PGRGRIEATNPCGEVPLLPYE------------SCNLGSINLARMladgrVDWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKIGLGVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLAEERGAFPAFTDSRFARSG--------------------------------PRRNAQVTSVAPTGTISLIAGTTAGIEPMFAIAFTRAIVGRHLLEVNPcfdrlardrgfyrdeliaeiaqrggvrgyprLPAEVRAAFPTAAEIAPQ-WHLRMQAAVQRHVEAAVS-------------------------------------------------------------------
>UniRef50_D0ME23(19-590:620) Ribonucleoside-diphosphate reductase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0ME23_RHOM4  E=1e-156 s/c=0.97 id=25% cov=68%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------WRRVARALAAAEPESERARWAERFYQVLYGFKFLPGGRILAGAGTRHRvTLFNCFVMGiIEDSLDGIFDSLKEGALTMQQGGGVGYDFSTLRPAGTRARTTGTIASGPVSFMHIWDAMCATLLSTGARRGAMMATLRCDHPDIETFVTAKHRPGV----LTHFNLSVQVFDEFMEAVRRDADWPLVFPAAA--LEDEGMGDGPIVYRRWTGTDgPVPCRVLRVVKARALWEQILRATYDYAEPGVLFIDTINRMNNLA-YREHITATNPCGEQPLPPY------------GACDLGSINLTRFVrapftpeadlDWEGIRETVAVAVRMLDNVIDVSGFPLPAQAEQARGTRRIGLGITGLADALIMLGLHYASEEARQLAARVMQTICHTAYRTSIALAREKGVFPFFERERYLESPF----------------IQALPEDIRKGIATYGIRNSHLLSIAPTGTISLLANNvSSGIEPVFAYRYTRYIlgLDGERraytltdyalrlwQRLHGDSEMLPEAFVDAQHLDPYD-HLKMQAALQPYVDGAISKTVNV------PADTPFNAFRQLYDWAYDHGLKgcTTY-------------------------------
>UniRef50_B1XZE5(38-629:1007) Ribonucleoside-diphosphate reductase n=11 Tax=Betaproteobacteria RepID=B1XZE5_LEPCP  E=1e-152 s/c=0.91 id=25% cov=66%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVAAALASVEAPEARELWTERFLAAQERG-FVPAGRIASAAGTTLSaTLINCFVQPVGDSIaepeegfPGIYTALTEAAETMRRGGGVGYDFSRIRPYGAWVGSTQSHASGPVSYMRVFDRSCETVESAGSRRGAQMGVLRCDHPDVEAFIHAK-----DKGDLKNFNISVGVTDVFMKAVEADTDVDLVHKAE----------PGEKQKAAGARQRADGLWVYRSVRARDLWDQIMRSTYDHAEPGVLFLDRINQDNNL-SYCETIAATNPCAEQPLPPY------------GCCCLGSVDLTHFvqrpfesdasFDDAAFAEVCATATRMLDNVLDATVWPLPAQQQEAANKRRVGLGFTGLGDALIMLGLRYDTPAARAMATHISEVMRDAAYIASSDLAQERGAFPLFNADLYLSG---------------NSFASRLPAAVKEHIRVNGLRNSHLLSIAPTGTISLAFadNASNGIEPPFSWTYTRKKReaDGTFKEFAvedhawRLYRHLKgadapltDAFVTALEMSA-EAHESMVAAVAPCIDTSISKTVNV------PADYPYEDFQGLYMAAWKSGLK----------------------------------
>UniRef50_Q120H3(19-627:784) Ribonucleotide reductase large subunit n=1 Tax=Polaromonas sp. JS666 RepID=Q120H3_POLSJ  E=1e-139 s/c=0.82 id=22% cov=60%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFVQPVGDSMSgsnqdgqpGIMDALRESAETMRRGGGVGYDFSSIRPVGARVKGTDSKASGPVSYMRVFDRMCQTVESAGARRGAQMGVMRVDHPDIEMFIDAKKTPdfsqmGLDKKDADglldlvrknqgfgwslrsafatlsNFNISVAVTDEFMNAVVNDSDFDLVHDAEPVEACPTKVCTDGK-----------ARFVYRTVKAIEIWTKIMRNTYYGAEPGVLFIDRINQDNNLR-YCEVIKATNPCGEQTLPPY------------GCCCLGSPNLTRFvsnpftlmasFDFDGLSKVVAKAVEMLDKVLDKTHWPLPQQASEAANKRRIGLGHFGLADAMAMLGIRYDSQQGADFAAHVSEVLRDSAYMASVNLAKTLGAFPFFDAEKYLE---------------EGTFASRLPEKIKDAIRMYGIRNSHLLSIAPTGTISMAFGdnASSGIEPIFSLRQQRNKMmaDGSRQifeledyayrqfKLSKGEDAKSDVFVTAMQMTVAD-HLRVLGAVAPYIDSAISKTVNV------PADYPFEDFQQVYMDAWRMGLK----------------------------------
>UniRef50_Q21U31(14-574:589) Ribonucleoside-diphosphate reductase n=1 Tax=Rhodoferax ferrireducens T118 RepID=Q21U31_RHOFD  E=1e-138 s/c=0.88 id=24% cov=67%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------WARVALAVSGAEPHHQN-DWRERFLAMLSDWRFLPGGRILAGAGTSRRvTLFNCLAMgPIEDSVQGIFNALREAMQCLQAGGAIGIDFSTLRPALALAQSSGAVASGPVSFMNVWQAANAVLEAGNRRRSAMLATLRCDHPDIEAFIDAKLDTGA----LSHFKLSVLLNDEFMQALQEDGPWPLVFP-----LGEHPIPVGGEVCERVWSDGGPPQLcmVHRRVPARALWEKLLQAQHASGEPGVLFIDRINRANNL-WYDEHLTVANPDGGVPLPPW------------GACNLGSINLSRFvqqpfaahpsVDLGGLRAVAAVATRFLDDVYDISLFPLKAQQKSALASRRIGLGVTGLADMLAMLGLRYGSAASIDLTREIMGAIRDTAYRTSVELAQEKGAFPACDKLKYGASPFVLELDR----------------ALQDAIAQHGIRNSHLLAVAPTESISLLANNvSNGIEPMRAFQAMRRVRGAEGQAVFFDVEDaacrqyqalhgpdapWPKHFVQAADVSAEDQ-LQLMAAVQSHVDNALSKTVYL------PASASVQDVGLVLQQAWELGLK----------------------------------
>UniRef50_Q8SCB8(51-705:705) Large subunit ribonucleotide reductase n=6 Tax=unclassified SPO1-like viruses RepID=Q8SCB8_9CAUD  E=1e-134 s/c=0.73 id=23% cov=83%
-------------------------------------------------------------------------------------------------------ERVRTLTKEGTYDK-VFDSIPDTIIEEMTKLAYSFNFQFQSFMACQKFYESYAVTqyDKDDNPIFvEDYEQHNVREALYLFQDDYVKAREMLIQ-----LMEQTLQPATPVYLNSGLgKRGELSSCYLFIVDDDtIESINFITDSVRQASKNAGGCAVDLTRLRPRGTEVNGVPNASKGVIPFAKNIEQSVSYFNQGGKREGSAVCYLNIFHPDIHEFSSSKKINASDKVRLDTLSIGVTIPNKFMELLKEDKYYYTFNVYDVKQKYGFTLNEIN-MSEYYDIFVNDDDIRKEKYYTRDIMTDIARTQLESGYPYVFYIDNANDNHPLKK-LGKVQMSNLCCEVTQLQEVSDifpylqSHNDTIGNDVVCTLGSLNLVNVVEKGLLKESVDSGIRSLSKVTDLMNVPfLPSVQKANDELRAIGLGAMNWHGLLAKNMLSYGSRESLDIANSLFSAIRYYSIKSSMELAKETGkVFKGFKESEYYTGEVfssyiqkshePRTKKAKKVLEKVYIPTEEDWNSLSKDVKEYGMYNGYLNNLAPTQSISYVQNATSSIMPVPSPIENRRYGNMDTYIPMPFMSPITQFFyesETAYKLDNKR-IINTSAVIQKHVDQAISTILYVE------SEIPTNKLVSLYYYAWEKGLKSLYYTRSQ------------TLKVIECESCSV--
>UniRef50_A7IYE5(34-864:865) Putivate ribonucleotide reductase n=5 Tax=root RepID=A7IYE5_9CAUD   E=1e-132 s/c=0.57 id=22% cov=82%
-----------------------------------------------------------------------------------------------------------------LWDKDVVLRYGFEDLKRLMKQAYGHKFRFKTYMGALKFYNSYALKTNDGKRYYERYEDRV--VLTAIHYSE----DFEHAESLVDLIIKGIFQPATPTFLNAGLLDaGKPVSCFILDVQDTMGSIGRIVQDSLQLSKRGGGVGIGFSNLREAGAPIKGREGQASGVIPVMKILEDSFSYSNQLGARQGAGAVYLNAHHPDILAFLDTKRENADEKIRIKTLSLGVIVPDVTFRLAKESEPMALFSPYDINKVYGKSLSEFS-VTEMYDTWLKDDRIAKTFIDARKLFQTIAEVQFESGYPYLMFDDAANRGNP-APNIGRIKSSNLCVtgdtqiltsrgyrradvlwetqedfevvvderartmnlkstgtsvqksskmfktatdadvykvttaegheikatewhkfyvdrdgelvkiplaelevgdrllaqgsespsrsenhyvpshkshatvhsiefygvedvydptvenghsviynglvtgncsEIFQPSSPSEFSEDsfftKTGRDISCNLGSLNVARlsALDTDDFHTAVKDAYKFLNQVAVQTEIGsSPTVVRGNRESRAIGLGQMNLHGALIELGLDYNSQEARDWFEWYMMRVTFSVISASVDKAEEMGSgFKGAEGSRWgdiisghrDRAMALIDRITASGNAMENSdvAWSYEWLRLLERFRLHGIYNQNLQAIPPTGSISYINHATASIHPVTSPVEVRKeGKLGRVYYPqYGVTNENVESIDSAYAIGPN-PIIDMYAVASPWVDQGMSLTLFF------PDTATTRDINRAQIYAHKKGLKSLYYIRTSAKS-------VEGTEVEGCLSCA---
>UniRef50_B1HS20(132-805:866) Ribonucleoside-diphosphate reductase n=28 Tax=Bacteria RepID=B1HS20_LYSSC  E=1e-131 s/c=0.70 id=24% cov=72%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNATGLAIVEKtPEKRQEWFEKFYDQLVSLKFIPAGRVIYGAGSeTDVTFFNCYVMPfVADSREGISDHRKQVMEIMSRGGGVGTNGSTLRPRNTLARGVNGKSSGSVSWLDDIAKLTHLVEQGGSRRGAQMIMLADWHPDIVEFIISKmqnprilryliENTTDEtiirlakeklnfkplsmqeeamyqgivnyksieglggfdtaiireaENKLRDggtytvhnpefltgANISVTLTKEFMEAVENDDDFELRFPAveeyskeemSAYNTEWHNVGDVREWEKMGYKIR-----TYRTIKAKELWNLINVCATYSAEPGIFFIDNANDMTNAKAYGQSVVATNPCGEQPLAPY------------SVCNLAAVNLAQFankdnqtVDYEALRETVRVGVRMQDNVIDATPYFLEENRVQALGERRVGLGVMGLADLLIYCEKEYGSEAGNALVDEIFKTIAETAYEASTELAKERGSFP------FLVGATDEETARLRKAFTETGFMEKMPAHIKEQILATGIRNSHLLTVAPTGSTGTMVGVATGLEPYFSFTYYRSGRLGKFIevkaEIVKEYldrhpeaneQELPEWFVTAMELKP-EAHADVQCIIQKWIDSSISKTVN------APKGYTVQQVEKVYERLYKGGAKggTVYVDGSRDSQvltlKAEENDMDQLSFEEE--------
>UniRef50_Q8V6N4(31-732:805) Ribonucleotide reductase n=2 Tax=Haloviruses RepID=Q8V6N4_9VIRU   E=1e-128 s/c=0.66 id=24% cov=73%
-----------------------------------------------------------------------------------------------------------------------------------------------------ILPARYFRKD-SEGNIIEGADDLFRRVAENVAGAEEDGDFDTWADEFEHQMKTLRFMPNSPTLMNAGTDMNQLSACFVIEPRDDMEDIFETAQQAALIFQSGGGVGYAFSHLRPKGAFINSTGGEASGPVSFMRVFDETCNQVKQGGKRRGAQMGILRADHPDIGRFIVAKRNEGE----FANFNISVATTDNFIEAVDAQESYTLYDpetdyeePYTVRELSAHFYSpeyqdnprdafdDGEgavveenlwrdyadeiecelygERVTLREKWEGHEGLRLEvgepmELPAAFIWDVMIDGAWRNGEPGLFNFEESNRQHSFDVEEYpefRMNATNPCAEQML------------VEYEACNLGHINLSLMlsedaptydeflsdkledvasgdlstreavewyfetaVDFNELDRTIEAGTRFLDNVVTQSDFPIPEITERVGGMRKIGLGIMGFAQMLYQMGVPYGTQDSYEVARCVMRYIDRRGTWASHRLALERGAFSYWDKSKYADPTE-YDEWFAARTGLDPE----DWAG------GFPIRNHNITTIAPTGTTSMIGNTTGGCEPAYNVANFKNVsediqgddllvefddyflrtleendldvdavkeeaetlmRNNEFDGVNDlsIPDEIAEIFVTTQDLSS-EQHGLMQRAFQEFCDSGISKTVNL------PNEATHDDVADAYQLALDEGrrgavIKglTVY----RDGSRDQQ-------------------
>UniRef50_P09853(506-1143:1144) Ribonucleoside-diphosphate reductase large subunit n=10 Tax=Alphaherpesvirinae RepID=RIR1_HHV23  E=1e-119 s/c=0.68 id=25% cov=70%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFHRLYDHQIVPSTPAMLNLGTRNYYTSSCYLVNPQATTNqaTLRAITGNVSAILARNGGIGLCMQAFNDA------SPGTAS-IMPALKVLDSLVAAHNKQSTRPTGACVYLEPWHSDVRAVLRMKGVlAGEEAQRCDNIFSALWMPDLFFKRLirhldgEKNVTWSLFDRDTSMSLADFH---GEEFEKLYEHLEAMGF--GETIPIQDLAYAIVRSAATTGSPFIMFKDAVNRHYIYDTQGAAIAGSNLCTEIVHPSS--------KRSSGVCNLGSVNLARCvsrrtFDFGMLRDAVQACVLMVNIMIDSTLQPTPQCARGHDNLRSMGIGMQGLHTACLKMGLDLESAEFRDLNTHIAEVMLLAAMKTSNALC-VRGarPFSHFKRSMYRAGRFHWERFSNASPRYEGE-----WEMLRQSMMKHGLRNSQFIALMPTAASAQISDVSEGFAPLFTNLFSKVTRDGETLRPNtlllkelertfggkrlldamdgleakqwsvaqalpcLDPAHPLRRFKTAFD-YDQELLIDLCADRAPYVDHSQSMTLYV--TEKADGTLPASTLVRLLVHAYKRGLKTgMYYCKVRKATNSGVFAGDDNIVCTSCA------
>UniRef50_B7KJK7(36-470:1123) Ribonucleoside-diphosphate reductase n=4 Tax=Cyanobacteria RepID=B7KJK7_CYAP7  E=1e-112 s/c=0.94 id=30% cov=56%
------VVKRDGSKAALNIAKIREVVEWACVG-KDVNPIALEAGLTTRLRNGITTREIQDNLINCALEMCSPEEPDWRYVAGRLHIWSLWKDTLanRGYQYGNYDQTVKTKIDHNQYDRRIL-VYSSEELQEAGTWINSDWDTDYDYAGAVLLTSRYLLPD-------ELPQEALLTCALLLASVETPENRLKWARKFYEAIAKRQISLATPILANLRVPNGSLTSCFISAIDDNLESIFSEVTNTAKISKNGGGVGINVSRIRATGSWVMNKPNASGGVIPWIKILNDTAIAVNQGGRRAGAVTISLDIWHLDVPEFLEMQTENGDQRRKAYDIFPQLVMADEFMRRVIHKQEWTLVDPYEIRTKFGVELAElwGEEFEQVYSKIETaihNGEITlYKRVNARELFKHIMRSQLETGMPYLAFKDTINRANP-NKHEGYIPGVNLC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2RTR9(1-790:1042) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Halobacteriaceae RepID=D2RTR9_9EURY  E=1e-110 s/c=0.51 id=21% cov=72%
-----------------------------------------------------------------------------------------------------------------------------------------------------ILPARYLRKD-ADGELIEDQEDLFDRVgkniALAEAVFEARKRDVEItvtpnqlkpdhprrdelatevfgkgttadddaeatlsiynvnkfaydtvvpelpdeirahvedvAEEFQGMMENLDFMPNSPTLMNAGDELQQLSACFVDSPDDDIDDIHQTAKEAAQVFQSGGGMGYAFWQLRPYGDAVGSTGGIASGPITFMRTYDQMCETIAQGGARRGAQMGVMRVSHPDVIQFIHAKNkdvslaetlrlNDPDDfthnsfqealdeareliddegkvpkhlrnavEGHLSNFNISVGITDDFMEALQNGEEFTFTNPRTGePHIATAETKELYDMFGLGDYVEVGEEL---SIPAEELWDDIVEGAHENGEPGVIYLERVNKQHSFdveKHPDHRILATNPCGEQPL------------EEYEACNLGHINLSTladleapdwrvwydehgeeydsledavdafleeAIDFEEFDRRIEMGTRFLENVVTMSDFPVEKIEQKVREMRKIGLGIMGLAQLYIQLGMEYGSETSNEVARQLMRHINHGSKWASHELAEERGSFDEWDNSKYANPTEYREWFEKQTGLDADE-----WED------GFSIRNHNTTTIAPTGTTSMVGNTTGGCEPIYNVAYYKNVSDdvqGDemlvefddyFLRVLEDndidvdavkeeaqeqmatnqfngveglstvPDAIGELFVTTGDLSAKE-HAGVQVACQQGVDSAISKTVN------APNDSTLEDAKDVFEYIYEHGGKGVTYYR----------------------------
>UniRef50_D1JF25(1-919:919) Ribonucleoside-diphosphate reductase n=1 Tax=uncultured archaeon RepID=D1JF25_9ARCH  E=1e-110 s/c=0.44 id=20% cov=73%
-------------------------------------------------------------------------------------------------------------------------------------------DLNLSANAAEVLKRRYLLKDELE-RVIETPSQMFARVAKAIARAEQNYGKSkaevkKIEQRFYLLMHSLEFLPNSPTLMNAGTDLGQLAACFVIPVEDSIEGIFGAVKDMARIHQSGGGTGFSFSRLRPKGDVVKSTGGVASGPVSFMRVFDVATDVIKQGGKRRGANMGIICADHPDILEFIRAK-----ERGEFANFNTSVAVTDEFMHAVDRNEEYELINPRTKEEV--------------------------RKIKAGEVFNEIVTYAWKIGDPGIIFLDEINRHNPV-SAVGRIEATNPCVTADSWVMTAEGPRQVEELIGKKFVAIINgeegesseegffetgvkqvyrLKTAEGFElrltadhpimRLERMTRYKVeaqwsnaRDLklgDKIIinnhrDFGNWGVkskytggegyliglllgdgtikklnpgkkeitEKIEKSSSDFcRCLlrGLfdadgSVQGnqskgvsvrLAQsdveilkAVQRMLLRFGIFSGIYMNRRgerkvkmpdgkggvkeyITkpqhelviskENILYFAERvgfsdiekmeklenairnykrkmnrerfvASVEEVVPDGVEKVYDvqipginafdangfivHNCGEQPLLPYDSCNLGSINVSKfvENGEIDWERLKEAVwssvrflddvidenryplskiekmtkanRKIGlgimglaelliklkiaydskdavlmaeklmqfitnearqcstelglekgsfpnfelsvwstydaMRNATVTTIAPTGTIGIIGNCSSGIEPLFAVAFVRNVMGgmleinklfeeiakekgfyskeliaeiakrGSIQDIAGIPEDIKRVFVTALDISP-EWHVRMQAAFQRYTDNAVSKTVNL------PSDATRGDVKRVFLLAYKLKCKgvTVY-------------------------------
>UniRef50_Q196Z5(4-628:630) Ribonucleoside-diphosphate reductase large subunit n=1 Tax=Invertebrate iridescent virus 3 RepID=RIR1_IIV3  E=1e-109 s/c=0.64 id=25% cov=70%
--------------------------------------------------------------------------------------------------------------------------------------IDESRNNLFDALGLQRLKDSYMKEDES------SPQERFAFIARQFCADDEP-----LAQRLYDYMSQHWLSPSSPQLSFGRTKQGLPIACFLPYLHDTARGLIDTWAEVSELSMIGGGIGLGVGI--------RQPDEKSVGIIPHLRTYDASCTAYKQGQTRRGSYAAYLDISHPEILSFLNTRRVGGDHNYKLLNLHNGVNVPDSFMKKIwilstlapfvkmdpcpttetlfkkavttLKDSRYFGADDRWLGEVSFAALAEQLDVVNRWDLIDPHTGKVKETIKATELWERIILTRAETGEPYIHWIDTSNRALPqFQKNLGlSIRQSNLCSEVVLP--------TDETRTAVCCLASLNLDYFDKWCNNEQFYLDVATYLDNVlqyfIDHAPPTLKRAVHSARSERAIGIGALGFHSYLQSKMVDIESLPAYLINKKIFKTISSHLERVNLELGELRGEAPDCVGT--------------------------------------GRRFSHMTAIAPNATSSIIMGNTSpSCEPFRANIYKQDTISGSFVTYNKHLKRLleeripdnqarervwssikmhdgsvqhlnqltvqeKKVFKTWPEI-NQLSLVMLAADRQKWIDQSQSTSLFFNP------DERISYVHKIHLKAWLHGLKTLYYFRSR--------------------------
>UniRef50_A7IY07(6-438:1103) Ribonucleoside-diphosphate reductase n=3 Tax=Chlorovirus RepID=A7IY07_PBCVN  E=1e-108 s/c=0.91 id=32% cov=55%
MNRLMVVLKRDGSKENISFDKILQRIQRLCWPINskpvykgsramtglSVDVSKIVASVCASIVDGISTVQLDELTADKSASMTT-EHPDYGILAARISVSNLQKQTHD--KITDAYAEIAHLLSNDFKEN------IEKHADEYQSFIDYDRDYDFDYFGFKTMERLYLTK--VNNKIVERPQHVYLRVAIGLWG-----SDIARVKETYDALSCRKFTHASPTLFNAGFKKAQLASCFLVTVEDSLGDIYKVLGDCAQLSKHGGGLGINISEIRGRGSRINGTNGESDGIVPMLKVFDTTSAYANQGGRRKGSFAIYLEPHHSDVMDFLLMKRNQGEESLRARNLFYAVWLNDLFMKRVETDAQWSLFDPSECPGLTDAF---GDEYAELYERYEAEGK-AKNVVKARDVWNTMVTTIIETGQPYVSNKDAVNKKNM-QMNAGTIRGSNLC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q01037(94-729:767) Ribonucleoside-diphosphate reductase large subunit n=6 Tax=root RepID=RIR1_SHV21  E=1e-102 s/c=0.59 id=24% cov=74%
---------------------------------------------------------------------------------------------------------------------------------------------------AKRFYDTYVLppRTEMNGK-YESIPHFFARIAAYCAwncimceplkdtlvyvqkrdWNVEIKTDMQIFKYFYKVISSQLVCCATPVMRSAGVAGENLSSCFIIAPTlDTEKStISSIFGELAPLLASRSGVGVDVTKFSFGGKNIH----------SCLKLINAQVEFFNDKSVRPVSVATYIEVWHCQIHEFLSAKLPENPD--RCNSIFQGVCVPSLFFKMYESDpnGLWYLFDPQDAPNLTRLY---GLEFEEEYLRLVSEKKY-KQSVTLKSLMFSLINTIIKTGSPYVISKEAMNKHHWYETQGEAINCSNLCAEIVQQPKQF---------TSTCNLANVCLPKClnssnfpytcsntaqFDFSKLEYAVQAAVFIINACI-LSPSPTSSATVG-QRERSMGIGCHGLADVFSEMGYGYLDLESECLDRDIFETMYYTAVKTSSEICSvgKGQPFAGFRKSKLAHGVFHWATW----DAMPQRVPMKQWIHLQDNIKKFGVFNSQFIALMPTAGTSQLTGYTDSFYPYFANMsskvsnkeeimkpnitFLKNVKpqdlctvrfyGGDVSMMPEDVSTRYKHFLTAFD-YCPEAQMRRASIRAPYVDQSQSLTLFLTEENVQSAKY----LKDLLLLGFRLGLKTiMYYCRVKKTTKLLQLEC----------------
>UniRef50_A5EVD2(40-573:573) Ribonucleotide reductase, alpha subunit n=30 Tax=root RepID=A5EVD2_DICNV  E=1e-93 s/c=0.65 id=29% cov=58%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RFFHYLARGYYSFSSPIWSNFGLARGLPISCFGSYIGDSIYDIMRTTAEVGMMSKIGGGTSAYFGAIRPRGSDIR-DNGKSDGSFNFSKLFDTVIDVISQGTSRKGQFAGYIDIEHGDIEEWLDIHT----EGNPIQLMYYGVCISHQW--------------------LAEMKAGDSEK---------------------RRIWAKVLQRKSETGIPYLFFKDNANAGRPdvYKDLNLPIYASNLCTEIMLPAS--------EEESFVCCLSSMNLLYYEEWKN-TDAVELLVYFLDAVMTefiekSADLPfLERARRFAMRHRALGLGVLGWHSYLQSQHLPFDSLAAMQKNNEIFQLLQRKTLSASRTLAEHLGEPEILRG--------------------------------------YGRRNTTLMSVAPTKSSSFILGsVSPSVEPLKSNYHVKDLAkikttyknpflvallaekgldtettwesillnDGSVQHLPDLSDEEKAIFKTFSEI-NQLSIIQQAAQRQKYIDQGQSINLMIHP------DTPTRDINQLYLTAAELGVKSIYYQHSMSAA-----------------------
>UniRef50_Q3JIM4(59-639:639) Ribonucleoside reductase, intein-containing n=47 Tax=Burkholderia RepID=Q3JIM4_BURP1  E=2e-93 s/c=0.60 id=19% cov=69%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVARALALAEPMATRSGAARRFYRNLLNGAFG-AGRIMARAGaAPDQTMASCFVHPIraPAALTrfhpNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALP------------GADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGR-ERIDATSPCGAQPLPPYGSAM------------LGAIDLSRFvrnpfgaggeprFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDR------HAHLDALRAGPPLPH---------AVCHAIERDGLRHSHLTSFAPVIGVSLAFGdhCSPGIEPARAWIEHRPVRAGAagapgmraenhahrlFRSLRGERAALPDYFATDADVAPGER-LAMRVALQPYVDAGIDNTLTLA------NHYSLEEVNALLFAAWRAKLKSV-AIRRADLARDAQPSDDDGV------------
>UniRef50_Q3KSU5(10-749:826) Ribonucleoside-diphosphate reductase large subunit n=5 Tax=Lymphocryptovirus RepID=RIR1_EBVG  E=5e-93 s/c=0.46 id=23% cov=72%
-------------------------------------------------------------------------------------------------------------------------------------------------------YDTYLYVGRSGKQ--ESVQHFYMRLAgfcasttclyaglrAALQRARPEiESDMEVFDYYFEHLTSQTVCCSTPFMRFAGVENSTLASCILTTP--DLSSEWDVTQALYRHL------GRYLFQ-RAGVGVGVTGAGQDGKHISlLMRMINSHVEYHNYGCKRPVSVAAYMEPWHSQIFKFLETKLPENHE--RCPGIFTGLFVPELFFKLFRDTpwSDWYLFDPKDAGDLERLY---GEEFEREYYRLVTAGKF-CGRVSIKSLMFSIVNCAVKAGSPFILLKEACNAHFWRDLQGEAMNAANLCAEVLQPSRKS---------VATCNLANICLPRClvnaplavraqradtqgdelllalprlsvtlpgegaigdgFSLARLRDATQCATFVVACSI-LQGSPTYDSRDMA----SMGLGVQGLADVFADLGWQYTDPPSRSLNKEIFEHMYFTALCTSSLIGLHtRKIFPGFKQSKYAGGWFHWHDWAGTDLSIPREI----WSRLSERIVRDGLFNSQFIALMPTSGCAQVTGCSDAFYPFYANASTKvtnkeealrpnrsfwrhvrlddrealNLVGGRVSCLPEALRQRYLRFQTAFD-YNQEDLIQMSRDRAPFVDQSQSHSLFLREEDA----ARASTLANLLVRSYELGLKTiMYYCRIEKAAD----------------------
>UniRef50_D1ABC6(64-547:1370) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=3 Tax=Actinomycetales RepID=D1ABC6_THECD  E=7e-93 s/c=0.71 id=22% cov=43%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FSFNSPVWFNVGTKSPwQVSACFILSVDDTMESILDWYKEEGIIFKGGSGAGLNLSRIRSSKELL-SSGGTASGPVSFMRGADASAGTIKSGGaTRRAAKMVVLDVDHPDIEEFIWTKAREEDKIRALRdagfdmdlggkditsvqyqNANNSVRVSDEFMRAVENDEEFGLRARLTGE--------------------------VIETVRARDLFRAMAQAAWECADPGIQYDDTINDWH-TNPETGRITASNPCSEYM------------SLDNSSCNLASINLLKFlreddtFDITRFVKLTELIITAMDISITFADFPTEKIAETTRAYRQLGIGYANLGALLMATGHAYDSEGGRSLAAAITSLMTATAYRRSAELAGIVGAYDGY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001923DF2(151-472:472) PREDICTED: hypothetical protein, partial n=1 Tax=Hydra magnipapillata RepID=UPI0001923DF2  E=4e-77 s/c=0.91 id=27% cov=33%
--------------------------------------------------------------------------------------------------------------------------------RRLQNSIRYDRDYLFDYFGIKTLERSYLYKlHFTKFKIIERPQHMIMRVAIGIHG-----EDIDSVIETYDLISQKYFTHATPTLFNAGTRRAQMSSCFLQAIDDNIESIFEAVRDIAFTSKWAGGIGVHMSALRCRGSLIRGTNGIASGVVPLCILLNKLAKYINQGGRRNGSIACYLEPHHADIFDFCDLRKNTGNDDDRARDLYLALWVPSLFMKRVRDDLTWSLMCPDQCPGLNKVHS---EEYVKLYEMYESEGN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_O31875(49-383:1084) Bsu nrdEB intein n=33 Tax=root RepID=NRDEB_BACSU   E=8e-76 s/c=0.86 id=21% cov=44%
----------------------------------------------------------------------------------------------------DLKEKLDYLIKNDYYEEEFLSKYTFEQIKSIYKIAYSYKFRFPSFMSAFKFYNDYALKTNDKTKILERYEDRVSIVALYCA-----DGDYEKAVEEVHTMMKQEYQPATPTFLNAGrKRRGEMVSCFLLEVGDSLNDISRAIDISMQLSKLGGGVALNLNKLRAKGEAIKDVENATKGVVGVMKLLDNAFRYADQMGQRQGSGAVYLSVFHPDITDFLDTKKISADEDVRVKTLSIGVVVPDKFIELAREDKDYYMFYPHSVYKEYGQYL-DELDINEMYDELVENPRVRKAKGNARKLLEQLAILRSESGYPYIMFADNVNKVHP-NEHISKVKFSNLC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1TJY2(690-979:1226) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=3 Tax=Comamonadaceae RepID=A1TJY2_ACIAC  E=1e-70 s/c=0.93 id=30% cov=31%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FDFDAFAASVATQVRALDNVLDVTFWPLPQQRAESAAKRRIGVGFTGLGNTLAMLRLRYDTDAGRAMAMRIAECMRDAAYAASVELAKEKGVFPKFDAAGY---------------LAPGTFASRLPAALQEAIRTHGIRNSHLLSIAPTGTVSLAFadNASNGIEPPFSWTYTRRKReaDGSTSEYAvedhawrlygalgGDVNALPDYFVSALQMPAA-GHIAMMEAVQPFIDTAISKTVNM------PADYPYEDFKNLYLHAWRARLK----------------------------------
>UniRef50_B1I483(6-298:1121) Ribonucleoside-diphosphate reductase n=1 Tax=Candidatus Desulforudis audaxviator MP104C RepID=B1I483_DESAP  E=2e-71 s/c=0.93 id=22% cov=34%
--------------------------------------------------------------------------------------------------------------------------------------------------GQKVFEARYAAKDE-QGRVTETFEQAVHRLARTTALAEKAQDRAAWEEKFAASIGGLLFVPSTPIWANIGKTDRpwQPGACFVLAVEDSLESMYQTLKDTAMVFKSGGGVGYNFSAIRPRGSMVRSTKGQASGVVELIRLYDASSGMVMQGGVRRGASMGILNIDHPEIIHFINSKR-----GGDITHFNLSVGVTDAFMEALERDEDWPLVFNGE----------------------------VHQTVPARELWDLITESAHACGDPGIIFLDRLQRDNPVPEK--KINATNPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0A8L7(16-347:1095) Ribonucleoside-diphosphate reductase n=3 Tax=Ectothiorhodospiraceae RepID=Q0A8L7_ALHEH  E=3e-69 s/c=0.80 id=20% cov=35%
--------------------------------------------------------------------------------------------------------------------------------------------------------KKYRLKSKDGQVIDETVDHTWQRVARALAEVEKtKKLREHWYERFLWALRRGA-IPAGRITSNAGawahKPATSTINCTVSgTIQDSMDDILQKVHEAGLTLKAGCGIGYEFSTLRPRGAYVSGAGAYTSGSLSFMDIYDRMCFTVSSAGGRRGAQMATFDVGHPDVLDFIRAKR----EDGRLRQFNLSLLITEEFMQAVEDDAQWPLAFPltkheaeTDNIDLTDSEQVIWREWPTTEPYISDEQGLVacriYRTVKARRLWDMIMTSTYDFAEPGFILIDRVNEMNN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0MFS7(759-1108:1354) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MFS7_RHOM4  E=1e-68 s/c=0.75 id=21% cov=38%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASLNLRKFqredgsFDVERFRAAVRIFITAMEILVDNAGYPSEKIAQNSHDYRPLGLGFANLGAMLMAMGLPYDSDEGRAVAGAITAIMHAEAYARSAEIAaiEHIGPFPGFEKNREPMLEVmrmhqaAVEDIHLSCPAYLKEAARESMARMVALGERYGYRNAQATVLAPTGTISFMMDCdTTGIEPDIALVKYKLLAgkgDGMFKIVNNtvpialrrlgyseeqikdilayieendtieGAPHLKEEHLPVFDCAFKpykgqrfihyMGHIKMMAACQPFISGAISKTVNM------PEHVTVEEIMDAYIQGWKLGLKalAIY----RENSKRSQPLSTRKEDKKGETSG----
>UniRef50_A3JKM6(17-341:1087) Ribonucleoside reductase n=1 Tax=Marinobacter sp. ELB17 RepID=A3JKM6_9ALTE  E=7e-65 s/c=0.77 id=19% cov=33%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YERVAQALSEVENKDLRAKHYKDFAWALKHGA-IPAGRIISNAGAQSHKPatstINCTVSGnINDSMNDILGKNHEAGLTLKAGCGIGYEFSTLRPRGAYVAGAGATTSGPLSFMDIFDRMCFTVSSAGGRRGAQMATFDIHHPDIIDFIQAKR----EDGRLRQFNLSLLITEDFINAVRDNADWSLSFPVTDKEVeeEDLDLTDTAKFVYRDFPVVKDyvmnaegkvACRIYRTLKAQFIWDTIMTSTYDYAEPGFILIDKVNQMNN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8MLU7(2-783:784) Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Alkaliphilus RepID=A8MLU7_ALKOO  E=2e-61 s/c=0.31 id=17% cov=86%
------VMKRNGRLVEFNPSKITNAIKKAMAetklGVDHNLSVKITEEIKEKIQNNAKpihVEEIQDIVEML---LMSSDRKD---VAKRYIIYRNERakiranqkssdeKLLTDEFISQYKHQIPPLNQLGNFVYYRTYsRWLQEEGRREYWWETVRRAVEYNCSlvptrreeAEKLFDNVYNLRQFLSGRTfwvggtsvaknypmsnyncsfvvidsFEAFRDLFyllmigsgvgARVLKEDVQNLPKiRTDYEIIHKDYVNISIKDREDNTSLVF-------SHNNSVKITVGDSKEGWIQSLDFFFKLLysneyRNIKTIIVDYDHVRPKGAKLKSFGGTASGHESLKNMFYKIDKVIKNSRKVNGSGKIKLRpIDCLDIANIIG--ENVVVGGVRRTAEMILIDADDK--ECVEAKSNLY-------KQIDGQWIVDQNII----HRQMSNNSIYYTEKPSREKLHWQIQQMRYSGEPGWINAEAAAKRRPN------MNGVNPCGEILL------------DSQGLCNLTTINVMAFVkedgtlDLEGIIEAQKLSVRAgyrMTCV----ELELPHWDKVQQRDKLVGCSLTGWQDLVNATTMDIEAQ------KKLLSMLRKAARNEVDAYAKEIG---------------------------QNIPL-------------------LVTTVKPEGTLSQLPTVSSGVHYSHSPYYIRRIRISAHDPLVKVCEELeYPVYPEVgqdWDTCSTKVVefpVKAPAGRTKydisaieqlenyklfmesYVDHNCSITIHVRNHEWEEVEEWvwnhWDDVVALSFLAlednfyqllpyesideeeYNKRLRSMKAFIPSLISKYEEKEMDLDIGSDSCDNGICPI
>UniRef50_Q9RRW1(902-1212:1418) Ribonucleoside-diphosphate reductase n=1 Tax=Deinococcus radiodurans RepID=Q9RRW1_DEIRA  E=2e-61 s/c=0.77 id=25% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CDLGAINLAAYvrgsdFDFAAFRADVRTCVRFLDDVLDVNVFALEDNRVASQDLRRLGLGVMGLADALIKMGLRYDNESGRQAIYDIMSALREEAVAESERLGQERGFYPVYERN-------------------------------REQVPHDPRRNVAVLTVAPTGTTSMLMGVSSGIEPVFSPFIWRKIGSeyrallaplfvellesypapkgmekdggwdwdkvteavsenhGSVVGLSFIPDALQQVFVCAHDISPVD-HVRMQGTVQRAFDdggqlaaNSLSKTINL------PNSASVDDVKSAYEEAYRTGCKgiTVY----RDGSRQFQ-------------------
>UniRef50_Q39UD5(10-271:279) Ribonucleotide reductase large subunit n=3 Tax=cellular organisms RepID=Q39UD5_GEOMG  E=5e-55 s/c=0.83 id=27% cov=29%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DFPSLAEDIKTAVRFLDDTIDANIYPLPAIELMHKGNRKIGLGVMGWADLLLRLGLPYNHPQSFALARSLMKFVRDTSRKASAELAEERGVFPNFAGSVYDAPDRPR------------------------------VRNATTTTIAPTGTLATIADCSSGIEPLFALAYKRNVLGTELTEINGYflnvakerglfsdelmqkvmeqgnlrgitgiPADIRRLFKTALEIPAAD-HIEMQAAFQEYTDNAVSKTVNL------PARATRGDVAKAFLLAYEKGVK----------------------------------
>UniRef50_Q2S696(22-281:932) Ribonucleoside-diphosphate reductase, alpha chain n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S696_SALRD  E=3e-41 s/c=0.67 id=24% cov=27%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADRFYEYMARGYYSLASPVWANFGLDRGLPISCFGSYIDDSMEAILNTHAEVGMMTKVGGGTSGYFGDVRPRGASI-TNNGTSNGTYPFAQLFDKIINVVSQGETRRGHFAGYIDIEHPDVEEWLNIQT----EGDAIQTMMYGVVVGDDWMEAMIDGDS-----------------------------------------DKRALWAKVVESRMNLGIPYILFRGNVQDGRPQvyKDKGYDVHASNLC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P50641(50-663:806) Ribonucleoside-diphosphate reductase large subunit-like protein U28 n=2 Tax=Human herpesvirus 7 RepID=RIR1_HHV7J  E=3e-50 s/c=0.33 id=21% cov=43%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIYLEIWHLSLLMWLDF----CEILPTTVQVKFCLILPEIFMERLKtENSYWSVFHKALAINLG---LYDESDFTSKYLECERTAEHAR--IKTETLLDNICRCL-RRGQMGFIFRKNIHKYSMLPQiasyclgnSMDVIpfeYGLNTAFRIALNLSYFVENVSEEQKSHT-NIDMFHYrDKIFNLKKMRKTVTELVLIGNAVID---YALENRDflmDGIVNARSLAICVTGLHSALMSMNLPFNSQLGCQLYRIVCENIYYSSVRTSMNCCKKGAePCSFFQRSKYAQGILHCDLYDNVEYTLPN----VLWTNLRSDIKKYGLRNLTFVSGSAMSKEFDLLNCSQSFCPIEGNKILKRS------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI00016C6541(209-705:706) ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Clostridium difficile QCD-76w55 RepID=UPI00016C6541  E=1e-31 s/c=0.28 id=17% cov=32%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CCNLTTTNLVNFIsndklDIDALKSVlrlsVRIALRM--TLIDA---ELKEWDKVMKSDRVIGVSLTGIMDMFNLTNMTY--RELGEILNTLRAVVHDEGERYSKVLGIE---APN-----------------------------------------------LMTTIKPEGSISTLPEVSSGIHFSHAPFFIRRVRISSSDPLYKAIEKDN-SFPIFDEIGSPnikviEIPVKSYAGKTKynvsaleqlelykltmenWTDHNTSITVHVREEEWDSvskwvyenfnsivgitflplteETYPLMPFEKISEEEYYRRLKDIKPIN-KDYLRLLESDSfeEQEIYENTCTSGACPI
>UniRef50_B9R6L5(162-683:684) Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Labrenzia alexandrii DFL-11 RepID=B9R6L5_9RHOB  E=3e-29 s/c=0.25 id=18% cov=49%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDFTQIRSAGERLKGYGWISSGDETFSKALFEICNILN---RRAGQLLTKIDIM--DIMNWL------GTTLSSRRSAEICVMPSSdpealDFAVAKKNHYSWKWPDGSLVEFPEDCFGEAYEEFIREitekgaYWnpqRAQSNNSLLFWEKPTKLEIKGLFQMMVDAGgsEPGF-----INAA-AAKARGGWFKGCNPCAEILL------------GDKSFCNLVEVDMAKFIgDEGGLWYAIYLAARAnyrQTCVNLRDGVLSDSWHELNEFLRLTGVGLTGI--------VKWIDGGSHKRPDIILGHCRYYAQEGVTTMADELG--------------LPLSK--------------------------------ATTTVKPSGTLGKIMDTSEGVHRPIAKYIINNVR---FSKEDPLVPLLRDAGYRVFDDPYASDGVLAAlpvvndgvkfdevngllidnesAVSQlerykllmdNYVDHNCSITVSYRVEEIP-------EIVDWLFENW---------------------------------------
>UniRef50_Q54CW7(261-670:758) Probable adenosylcobalamin-dependent ribonucleoside-triphosphate reductase n=2 Tax=Eukaryota RepID=RTPR_DICDI  E=4e-28 s/c=0.31 id=19% cov=46%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DYSSIRKKGEPIKGFGGVCCGYEPLKELHDEIRALLN--------KCIGKPISSTNIVDLMNLIGKCVVSGNVRQAAEIAFGDPNS--QEYIDLKNYQ-INPQRA---SFGWCSNNSVFAELGMDY-----------------SKVCQSILHNGEPGLAWLDNMKAYSRmvpteLDYKDRRAMGGNPCLEQTLESYE------------LCCLVETFPNNHESLEDYLKTLKYAFLYAKTV-TLGSTQWPDTNKVLLRNRRIGCSMSGIAQFIHFNGLH----QLKDWCVNGFKLLNELDEKYS------------------------------------------EWLAIPKSIKR--------TSIKPSGTVSLLAGATPGMHYPISEYYIRRIRiqkesnlipplveagyhvepafENSTNVVVEIPIHSGKGIRSANSITMWEQ-LSLASFLQKyWADNQVSCTVSFDPIK----------------------------------------------------------
>UniRef50_A7KA98(15-575:627) Putative uncharacterized protein Z838L n=1 Tax=Acanthocystis turfacea Chlorella virus 1 RepID=A7KA98_9PHYC  E=2e-27 s/c=0.23 id=16% cov=39%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WDVSGIRPPGARLKTFGGRASGPKPLVELFWFVVKTFKGAAGRK---LTTLECH--DIMCKIGEIVVSG-GVRRSAMISLS-DLDDDRMRSAKSG-PWWETAPHRAlannSAVYNTKPTVG-KFMTEWLSLYNSHAGERGIVN-REAMKKIAKK--------------HGRDSSFE------FGTNPCAEIILRPYQF------------CNLTEVVVRATDTKETLMKKIRVATIIGTVQSTFSKFPYLRkiWKKNTEEERLLGVSLTGIFD---NTNMCTNTKD----LEDTLESLRDYSKQVNSEFAERLGIPKS----------------------------------------------TAITCVKPSGTVSQLVDSASGIHPRHSKYYIRR-------------------------------------------------------------------------------------------------------------------
>UniRef50_Q035U1(228-664:748) Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase n=16 Tax=Lactobacillus RepID=RTPR_LACC3  E=7e-26 s/c=0.28 id=21% cov=26%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDITNIRPKGARIHGFGGTASGPMPLIEMLldinkllnarvgqhltavdatdigNLIGKTVVAGNVRRSAEM---SLGSADDEDFITMKQDQKQLYHHRWASNNSVAINTQF-----------------------------------------------------DAYSPIALAIAKNGEPGIVNLelsrrfgriaDRENAENDPD-----VEGTNPCGEISLANGEP------------CNLFEVFpVVAVEQGWKLKQAFTLAARFAKRV-TFSHYDWQVSRDIIKKNRRIGVSMSGIQDWF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8YMB4(29-375:375) Ribonucleoside-diphosphate reductase (Fragment) n=2 Tax=Human herpesvirus 3 RepID=B8YMB4_HHV3  E=2e-25 s/c=0.35 id=20% cov=21%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFTALACQKIVPATPVMMFLGRETGATASCYLMDPESITVGraVRAITGDVGTVLQSRGGVGISLQSLN-----LIPTENQTKGLLAVLKLLDCMVMAINSDCERPTGVCVYIEPWHVDLQTVLATRGMLVrDEIFRCDNIFCCLWTPDLFFERYlsylkgASNVQWTLFD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7FY00(66-812:926) Ribonucleoside-diphosphate reductase n=2 Tax=Bacillariophyta RepID=B7FY00_PHATR  E=0 s/c=0.93 id=29% cov=92%
----LHVSKRDGRLELLDSTKLLQRLTDLSDGLDMRFLNLVAltESIVRGMYPNVTTHEIDVLAAETAASLGTQ-HPDYGRLAARILITQNHKTT-----PTCFSEAIETLYNSGKgFIDHKVGELVRRRGPEIDSRIVHERDLEMTYFGYKTLERAYLLKKDNGNQVLERPQYLMMRVALGIHCTSKMSSRseddcLEAAFETYDLMSRGFFTHASPTLFHAGTTHPQLSSCFLVQMsEDSINGIYDTLKRCAVISKAAGGIGLSVHNIRARGTPIQGTRGVSNGLVPMLRVFDVTSRYVDQgGGKRPGAFAIYLEPWHADIFDVLSLKKNHGKEEQRARDLFYGLWIPDLFMKRVEEDDVWSLMCPHQCPGLAHCY---GAKFEALYQHYEQEGKFVRQ-VRARELWGAILESQIETGTPYMLYKDTCNTKSN-QQNIGTIQCSNLCTEIIQYS--------DQEETAVCNLASICLPRfvvsergtfgsispesgsaFFDHEALHRAAKIVTRNLNSIIDVNSYPVDGAKTSNFKHRPIGIGVSGLADAFLRLGLPFTSAAAKKLNEAIFETIYHAALEASAELAEKEGPYETFAGSPASQGKLQFNLWGLSDDETPshkyalaketpvpiqmypnsSNVCGYDWESLRRRIVKTGLRNS--LSWASTSVSSLSAQT-------FRNQMMRD--GGSVQNIPDIPDRLKELYKTVWEIKMKD-IIDMGADRGKFIDQ----NPNM------------DKLTAMHFYAWKKGLKTgMYYLRTKPAVNAIQYTVEK--------------
>UniRef50_B2V806(4-792:850) Ribonucleoside-diphosphate reductase n=2 Tax=Aquificales RepID=B2V806_SULSY  E=0 s/c=0.82 id=26% cov=90%
-HKNRIVVKRDGTQEKFQMKKLVDAIFALLEGLDLPDdyeiVFKITKELDLKIPEVVTTEELDYLVLKAIEHLIPTGSI-YDTIATRQLLKIINRRIERRFS--SFKDYINYAVNEKLLKPELLN----FDIDLLESKIDYSRDNNLDYFGLSTLKDRYLTKDR-NFETIEKPQWFFMRVAMGIGNTE------EEILKIYDKLSNLEYLHSTPTLFNSGTLTNQYSSCYVNVVDDSLESIMDKAKETAFLAKYAGGVGTDITRIRATGSKIHSLNAKSSGIIPFIKIFDTIVNAIQQGGRRRSSQVMYLQPWHLDVEAFLDLRETTGNPYFRTPSLNTALWMPDEIMRRIKEGEPIYLFDPAECRELVTSY---GEEFAKKYqeciEKAERGELELWKKIDSRDFYKKYLFKLAKTGHPWLTFKDAHNRHNPCPKYS-VINSSNLCTEISIPNSP--------QSTAVCTLASVNLARHlkkveretsdvkreelspnekntshlltyspthsIDWDKLKDTLETMVVALDNILDKNFYPSEESRKNTMDLRPIGIGLMGFHEALIYLGIPYDSDEAIELAKEIAKFMRETVYRKSEELAKERGAFPhYYEVSK---------RESEKVKSEELNPNEKTPTHLLTYSPTHPYnypprRNAVLLAIAPTASISIIAGTSSSIDNYFSNIFSRDTLSGKFIVVNKplmkmleekgiwneemlekikanqgsiqYIDELegvvdKRLFKTAYEVSPYRQ-IDIAAAFQQYIDQAVSKSLYIEEDLR-------DDMENIYMYAWEKGLKSTYY------------------------------
>UniRef50_B3RGP4(4-770:771) Ribonucleoside triphosphate reductase alpha chain n=5 Tax=unclassified Myoviridae RepID=B3RGP4_9CAUD  E=1e-160 s/c=0.74 id=34% cov=97%
------VIKSNGCEVAFDPERLNKAAIFGDDG--NGNWSHIALDAYKRLYDGCTTKEVNQAIIDSCVSRKDEEH---SRMAGRVLIGQIYKEAFGGFtKIPSLPSFYNTMVEKGYWEDM---GYSFTELNTLDAVIDHSKDLGYGYAVLKQFRDKYGIKDTLKDTLFESPQMMFMGIAMAVMKNMPKERRINDVVKLYTYLSDLKINAPTPYLNGLRTGKTGYASCCVIKADDTAKSIGVAREVAYTMTVNQAGIGYYLSS-RSAGDGVRGNTIKHMGKIPYYRGIDAGVKENRQQ-SRGGSATVSFLALDPQIDELIRLRNPMTVASKRINTMDYSIGINRSFINRVAKNLDWMLVSYKHAPQLHeGIFTMSMEEFDAEVDRIAKDDSIPKTWIRARDLAVELLTQRIEVGRLFVYWTDEMNRHTPFK---DVIYSSNLCAEIALPTKGYSDMRNifkhdvDDGEVALCFLSSLVAGR-VTPEEYEDVAYYTVLMIDNVMEIMTYPYENMESTVKKRRSIGVGLTNVAHFIASHKVTYGSPESKQLVHDLAELHSYSLHKASLRLAKERGVCEWMHKTKYPEGWLPIDTYNKEVDSVVKDPsLKQDWEGLRKEIIENgGLRNSVLEAYMPNESSSLATNTTNGVYPVREHIIFKKSPQGQVLFIVPDYDELKEYYTSAWDVDTND-MIDMYAVIQKFTGQAISADLYIDYTKLKDGKISMKEQLGYLIRATKFGMKTWYYLNSRVGAGDSLAEelhakkqaedetrknypliADSSVEDPYCESCA---
>UniRef50_UPI0001792B32(4-766:766) PREDICTED: similar to AGAP010198-PA n=1 Tax=Acyrthosiphon pisum RepID=UPI0001792B32  E=1e-156 s/c=0.73 id=23% cov=93%
LKKHLYVQKRDGTIEKVHYDEIIARIKQLCYGLEKIDPAATAIHVIKKcLFAGITTSQLDDAAAEMAITM-ATIHPDYEKLAARIAISNLHKQTKEKFSDVIDDIHKNDDYWNTGLSDDI-YEIIMKNKDRLNEAINYENDYILDYFGFKYLTQNFLVKSE--NQTIERPQHLFMKVAVGIHG-----DDIDSAIETYKMLS-QKLCMFSPVVMQLQPAARKLNVSVISHysvamIADSIDGIYDTLNRLSTFILPYSSVAVHVHKIRAAGTYIKGSNGKSSGLPLMLKQYDSMV-HCKETLERPKSikgVAIYCELWHADIMKIIDQIRKTTIADIKLKNSQLALWIPDEFMRRVENDQMWSFMSPDHCPGLIDVH---GEEFDNLYKEYElKSKSFVMRQIEAKKLWSQIIQSQIETGLPLLLFKDACNAKSN-ESHLGTIQC---------AGRNGDTVQfTASDEVATCTTASISVDMFltseniFDFSKLKETAKKITYDLNKIIENNNVILNKEDQLKLGLKqnqlAIGIGIQGLADLFIKMRYPFDNKEARYLNIQIHETIYYGALEASCELASKNGPYKTYPNSPTSKGLLQFDLWNVKPSNL------WDWNSLKTKIAQHGLRNSLVTVTSNTEVESTIFGNVNSIEPLDTNVKRRyislgESKPKEIQVVNPYllkdlhdrklwdeklipelvnnmgsiqeinlPDDLKQLYRTKWEI-DQKVLVTMAADRAPFIDQSQAFSLNMVKANEDI-------ISEMHISTWKMGLKTgVCQLRIKQTEEDLRD------------------
>UniRef50_C6QBB0(15-567:809) Ribonucleoside-diphosphate reductase n=2 Tax=Hyphomicrobiaceae RepID=C6QBB0_9RHIZ  E=1e-146 s/c=0.95 id=24% cov=65%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------FRRVALAAASAEKGGKRQQqkWAGTFYEAMADFGFQPAGRILAGAGTDRNvTLFNCFVLgEIADDLSSIFESVKEAALTMQSGGGIGHDFSTLRPRGAPVKSIGADASGPVSFMDVWDAMCRTIMSAGQRRGAMMATLRCDHPDIEAFIAAKA----DSQRLRNFNLSVLVTDAFMDAVRRDAPWDLIF----------------------------SGKVYKTIPARALWDQIMRATFDYAEPGVIFIDRINAANNLQ-YCETISATNPCGEQPLPPY------------GACLLGSINLARlveepftataHVDIAKLEARVATAVRFLDNVIDISRYPVPQQAQEARAKRRIGLGVTGLADALIFLGLPYGSAAAREQAARWMAIIQNAAYRASAALAAEKGAFPLYDANV----------------VLTRPNITRLDDDVREAIAANGLRNGCLTSIAPTGTISLLAGNvSSGIEPVFDFVFRRRVLsdgGGAEEETVEDFAHrafrdafgddavLPEAFVTAETLTPSE-HVAMQATLQPYVDSAISKTINC------PEDISFESFRDIYIEAYDSGLKgcTTY-------------------------------
>UniRef50_Q8SCK6(21-779:779) PHIKZ306 n=2 Tax=phiKZ-like viruses RepID=Q8SCK6_9CAUD   E=1e-141 s/c=0.67 id=33% cov=98%
------IIKLDGTEEAYSPAKINGWGEWAAQHLGDkVDWSSVVMDAVQALGDKTSSQELQLQLIE---ECLNRKTWSYYLMAGRLYAIYLRKKFYGLNGIPTVKALQTRMRKDGIIVKL---DYSSKEYAQIEKIIDHDLDLLCPHFSLHHIRGKYALRNRKTGQEYETAQFVYMRMAMALAEKEPAETRMTHVENYYKLLSNKILSAPTPNYVNLGTKLRGFASCCLFASGDNGVSLAMGDYIANIMTQSSAGIGVNL-MTRSIGDPIRNGLIIHQGKKPYIDVIGKAVRANLQNG-RGGAVTCYYSAFDPEADMITQLRNPRSTEDRKNRDLHYAFLSNKFFAkKAAQKDGMIFVFNPFTAPDLHDaFYSGDIDKFIKLYEKYEADPKFEKTYVNARDLLKSMLVEAYETGTIYSAQIDELNHHTPFK---EPIYSSNLCLEIAEPTKPYYRMEDlyssedhGRGEIATCSLAAIAVDNVPDKQTYEMAAYYALKMIDYCILNAEYAFPHLALTAKNRMSAGVGIMGLATHMARAGLKYSSDAGKAEIHFIAERHMYFLIKASLKISKERGNAPWIHKTKWPEGWTPRKTYNKSVDTIIEGGFEelYPWDELEKEIKENgGIAHSVLAAYMPGEASSKALGSTNGPYPVRRLILNKTDNGARVLWAAPYGDDDSYVYESAYDIPTKD-LIDCYAIIQKWTDQTISADLY--RRIVGSEKISSNEMLGNHFYMVKRGMKTRYYVNLETAAGLDIKSLERAVEvtntEVGCAGGSCTL
>UniRef50_B3SZX1(3-618:817) Putative Ribonucleotide reductase, barrel domain protein n=1 Tax=uncultured marine microorganism HF4000_001A02 RepID=B3SZX1_9ZZZZ  E=1e-140 s/c=0.81 id=23% cov=68%
-----------------------------------------------------------------------------------------------------------------------------------------------DSLGADVLKNKYLAPWENH------PYELWQRQAKALASVErTKKLRDTWEKKFYYILEDFRFTPGGRIMHGAGREDitTTLNNCYVVGIqDDSINSIYRTIEEEARTYKYGGGCGHDLSVLRPSGDAIKGTGGESCGPVGFMNLFSENTNTIAQHG-RRGANMQTLRVDHPDIEKFIEIKTG---DIHMVKYSNISVLLTHRFMEAVENDSEFDL------------------KWNDQ----------VYKTIKARQLWNKIIEHAHTSAEPGLLFWDTMIDYHN-AEYCSPLVSTNPCAEQPLP------------DGGCCNLGSINLERFVDgegnfmIDEFKDTVGIATRFLDNVIDYNleRHALESQKDNATKDRRIGLGILGLGDMLVRMGIKYDSDDAIQTVEQVMQIFRDGAYETSVELANEKGSFPSFDWAGYRKSQFIKNLPRN----------------LNNKIKENGIRNSTVLTVPPTGSGAIVARVTSGIEPIFATSYTRRVKKNdGFGKTFNEYkvyhpiikklfgndENLPDYVISAHDIDPYSR-VKMQGVIQKYIDSSISSTVNLKE------DVTLETVADIYMTAYKTGLKgiTVYREGSREG------------------------
>UniRef50_C1DPR2(807-1300:1338) Ribonucleoside-diphosphate reductase n=14 Tax=cellular organisms RepID=C1DPR2_AZOVD  E=1e-134 s/c=0.98 id=30% cov=57%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKRKGAVCAYLETWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVFEDGQWTLFSPSDVRDLHDLTGRAFEERYEYYEALTQYGKIKlFKTIAAKDLWRKMLSMLFETGHPWLTFKDPCNLRSP-QQHVGVVHSSNLCTEITLNTS--------DSEIAVCNLGSINLVNHIndgrlDTEKLSRTVKTAVRMLDNVIDINYYSVDTARNANFRHRPVGLGIMGFQDALYLQHIAYGSEAAIAFADRSMEAISYYAIQASCDLAEERGAYSSFEGSLWSRGILPLDSLDILAEQrgtkyiEVDRSSTLDWAPLRERVKK-GMRNSNIMAIAPTATISNIVGVSQSIEPTYQNLYVKSNLSGEFTVINPYlvhdlkarelwdgvmvndlkyydgsvqqieriPTDLKALYATAFEVETK-WIVEAASRRQKWIDQAQSLNLYIAGASGKKLDVT-------YRMAWFRGLKTTYYLRALAATSAEKST-----------------
>UniRef50_A7HCF4(53-717:929) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=5 Tax=Cystobacterineae RepID=A7HCF4_ANADF  E=1e-123 s/c=0.67 id=21% cov=66%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KMSFNSPVWFNVGVeEHPQCSACFINSVGDSMDSILRLAHTEGMLFKYGSGAGSNLSKIRSSKERLSG-GGEASGPVSFMRGFDAFAGVIKSGGKtRRAAKMVILDADHPDIGEFVSCKadeekkawalidagydggfnvKGGAYDSVFFQNANHSIRVTDGFMRSVLDDRAWELTARTDGHAL--------------------------ESIRARDLMRQITEAAWLCGDPGMQFDTTINAWHTC-PATDRINASNPCSEYMFL------------DDSACNLASLNLMHFrgidgaFDVESFKRAVDLTVLAQEILVSNAKYPTEQIGKNSEDYRPLGLGYANLGALLMASGLPYDSDGGRACAGAITALMTGEAYAMSARIAERMGPFAGYERNRepfLGVVRKHANHVDRIDPTFVERPLldaaRDAWGDALRLGTQSGYRNAQLTVLAPTGTIGFMMDCdTTGIEPDIALVKYKKLVGGGVLKIVNNtvplalqrlgysadaiastlefidkvetiegAPELRDAHLPVFDCAFKpqngtrsihyMGHIRMMGAVQPFLSGAISKTVNM------PTEATPADIETAYLEAWKLGLKAIavY----RDGCKRSQPLNTGKAKEEE--------
>UniRef50_D2R4B9(55-746:1041) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R4B9_9PLAN  E=1e-121 s/c=0.63 id=21% cov=63%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPQGSACFIQSVDDNMEAIMRLATSEAMLFKFGSGTGTDLSTLRSHREKLSG-GGKPSGPLSFMRVYDQIAAVVKSGGKtRRAAKMQSLKVWHPDILEFVECKWKEERKAHVLiekggyeanfngeayssilfQNANLSVRLTDEFMQAHEKNEKW-----------ATHWITDASKEGPVYE--------------ARWLLNRMAECAWQCGDPGVQYDTTINKWHTC-PNSGRINASNPCSEYMFL------------DDTACNLSSINLMKFreadgsFNVDRFKTACRLFFIAQEILVDHASYPTEQIARNSHAFRPLGLGYSNLGSLIMSNGLPYDSEAAYGLCGSVTALLHGAANLASAEMAAVVGPFEGYEANRepfLRVMQMHRDAVEDINPAGPadlQEAARATWDQVLALGRRTGFRNAQATVLAPTGTISFMMDCdTTGIEPDIALVKYKQLAGGGMLKIVNGtvpmalgklgyddpqikgilkYVNENDTIEGAPELADehlavfdcafkpangvrsinWRAHIRMMAAAQPFLSGAISKTVNM------PTDVTPADIGDAYTWGWQLGLKalAIY----RDGSKQSQ-------------------
>UniRef50_C8WXT6(309-861:1065) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WXT6_ALIAD  E=1e-121 s/c=0.79 id=23% cov=62%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FCLSPGDSRSTIARTLGDMWEAMRDGKRVSLVLSSLRPRYSYVRGVNGRSSGAYSWGLLYDKgnqvfgegfgpvgvgeimsvGCQLTLQGGSRRGALMLILNDRHADLPKFIRAKQVDGV----ITGANISVGVSEEFMQAKRRGESWQLgFVPPSHREAFDGDFGRWLE--------EGKPFEVTETISAAKLWRDICESAWKSAEPGVVFLGRANAMSN-SWYFNPLVATNPCGEQPLPPY------------GICNLGAVVLARFANgfrdsgvrtefsdpereayvrslllekfpadeaefllhhirWEELELTTRRGIRFQDAVIDATYYPFEENRQNQMSERRVGLGIMGLHDLMLYCGIRYGSEESVKLIDVLMGLMAEWAYLESVELAKEYGPFPKFDAEKFLQSGFMRHMAAERP-------------HVVEAIRKHGVRNVTTMTIAPTGTTGTMVGCSTGCEPYYAWSYFRNSRLGLFEEhaaIVEQYrrehpseESLPPYFVTAMELTPEE-HVRVQAALQRWIDSSISKTCN------APHSYTVEDTVKLYDLAYELGCKgiTIY----RDGSRSEQ-------------------
>UniRef50_Q6UDJ2(157-810:811) Ribonucleoside-diphosphate reductase n=2 Tax=Iltovirus RepID=Q6UDJ2_9ALPH  E=1e-119 s/c=0.66 id=26% cov=67%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FFMALCRQEIVPPTPVMLFAGTESRSYASCFLLDVrgrhtRDVLTSIAE---EIIPVMHSHGGIGLYMDCD-------SNWDDNSSGMMLALKALDSIIAASNAVSARPSGLCVYVEPWHRDIMKILRCRGVlAGNEETRCDNTFFALWMPDLFMKRFEANGTWTLFDGR-AAHLSDLY---GEEFEKEYELLERKN-VGIATYPARDVMFALIKSAVSTGTPFVMFKHAVNRNYFFDMAGRAMKCSNLCTEIVH--------MTDDESVGVCNLTSLNLAAFvtrrnalpgtppigtFDYSSFRDACAVATVFINALMSLSNLPIKRATTGNERLRSIGIGVQGFHTACLLQGFGLDSVEACRFNGKLFEALALTTFQTSCRIC-ELGmnPFRGFSESKYAKGWLHMDGWPARHLYFDG------WDRLRENIKAYGLYNCQLVALMPTASSSQLTEVSEGIHPVFGNIFSKITTTGEDIQLNvalmetieclypnkaerrDILERLHKnkwstrgafgaalpsqhpltKFDTAFE-ADQEHLLRLSADRAPFVDHSQSTTLYVVEEDDGAVRASR--VAHLLTTAFKYGLKTgMYYCKVRKATD----------------------
>UniRef50_Q2S5T5(68-725:894) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S5T5_SALRD  E=1e-117 s/c=0.65 id=23% cov=67%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WTQRFYQLLSGkglgtgpFPFTPGGRIFANAGTGLGKatLINCFVSGFqghdQDSMDEIQAELTRQAKILASEGGYGFCAHIMRPRGARIGGVGSMTPGAVQMLDVWNKQAATIVAGSgmksdrddvkdkIRKGAQMVTMGIWHPDIIEFIEAKQEPG----RLHKFNMSVLITDEFMEAVKNDDTWALRFPDYENEK-EFYKQHWDGNLKAYQ--EKGGTVKTWTDPatgepavyeAREIWNRIMDSTYNRNEPGVIFVDTINKENNL-GYVEHINATNPCGEQVLPVG------------GVCLLGNLNVTQLVdreagtiDYDLVDDLVPLAVRFLDNVNDLSYVPLEEQQRNLQEKRRIGLGHYGDGSALMMMKTRYGSEEGARVMREFQEHLANQAYQASARLAEEKGAFPLFDKDEYLSSPFVQRLSDKT----------------KEMIGDLGLRNSHLLSIQPTGNTSTLGNApSSGIEPVFMHSYIRTSEQPALPDGINRPPMSPNAYEVGQDIDadgtawtaeeqgdetvlrcqeeghthwqihptrdickdqevkdyavrhmetdgtwdpdadwavttrdlDVDDHLTQMKALAPFVDSSMSKTVNV------PNDYPFEDFKELYKKAHDTGvIKgvTTYRAGTMSAVLSGEDD-----------------
>UniRef50_Q1ISM3(26-757:1004) Ribonucleoside-diphosphate reductase n=3 Tax=Bacteria RepID=Q1ISM3_ACIBL  E=1e-116 s/c=0.58 id=21% cov=61%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GYTRPQCSACFINSVHDSLDSILTLAKTEGMLFKWGSGTGTNLSPLRSSNEQLSG-GGTASGPLSFMRGFDAFAGVIKSGGKtRRAAKMVILNIEHPDIVEFIDCKAKeeakawalmqqgydgsspdaEAYSSIFFQNANNSVRVTDDFMYAVVRDADFS-------------------------TKAVKSGDVVK-TFKARWLLSKISEATWQCGDPGMQYDTTVNRWH-TSKNTARINASNPCSEYMFL------------DDSACNLASLNLMKFapngtFDVAAYRHACAITITAQEILVDNAGYPTESIMKNSHDYRPLGLGYANLGALLMAAGLPYDSDAGRDYAACVTAIMCGEAYLQSSKIA-ELGqpltpatpitqsveitgsACPGWYVNRepfLDVIRMHRASVNninqKNVPAPVFEAAKATWDEALQHGERHGYRNSQVTVLAPTGTIGFMMDCdTTGIEPDLALVKYKKLVGGGMIKIVNntVPAALFKLGYTsdqanatvsyidatgtiegAPHIKDEhlavfdcsfkpakgtrtisyMGHVKMMAATQPFISGAISKTVNL------PKDATIDDIMEAYIQSWKLGLK----------------------------------
>UniRef50_Q3AEA3(3-912:1101) Ribonucleoside-diphosphate reductase n=2 Tax=Bacteria RepID=Q3AEA3_CARHZ  E=1e-109 s/c=0.44 id=23% cov=72%
--------------------------------------------------------------------------------------------------------------------------------------------------ALKVLEARYLARNE-KGEVIETPEEMFWRVARAIAQAEKNYaenDEEEIAREFYNFMTALDFLPNTPTLVNAGRPLGQLSACFVLPVGDSMEEIFDAVKYSALIHKSGGGTGFSFSRLRAKGARVRSTGGIASGPVSFMKVFNAATEAVKQGGVRRGANMGVLRCDHPDILEFITAK----EDNRDITNFNISVALTDKFMKALEEDGEYELIEPSTGE--------------------------VVGRLRAREVFERIARNAWKNGEPGVIFIDRINAAN-VVPELGEIESTNPCVtgdtlvftdkgliearklevgmkvwsgdgwneikevinngvkpvlklklktgleikvteehkiftgegwkeakdlkvgdklylpvsypELDFPVkeendfYEFLGYFLGDGSLSVSNHVSLHVGNdkelalYFkeKVEKYAGAAYLIERDGQYIIDVHR------KEFAEKIKKIfGIEITdskekdipssllavnseamkallrGLFSAdgsvydangsitvalsstsypllrkvqilLLSLGIPstltgekdqdvkiikgneYETlptyrliisgERASLFFNKIgligekkkkflelmagkttYSTLNNHLYQEivSIEPAGEEEVFDITAPPKYTwitngilsldcgeQPLLPYESCNLGSINLANmvKDGEIDWEHLEKTVKlavrfldnvidvnhyplpeiekmtkktrkiglgvmgfadmliklnipydseealnladkvmefinkkskeasaelarvrgtfpawkksvwaKKGlkLRNATTTTIAPTGSISIIAGVSSGIEPVFALAFKRHILDrkdivevhrlfeqharengyyseklmnevaktGRITGIAGVPEEAKRLFVTALDIAP-EWHVKMQAVFQKHTDNAVSKTINM------PNSATVEDVKESYLLAYKLGCKglTVY----RDGSREEQ-------------------
>UniRef50_UPI00019240FD(3-389:416) PREDICTED: similar to ribonucleotide-diphosphate reductase large subunit, putative, partial n=1 Tax=Hydra magnipapillata RepID=UPI00019240FD  E=3e-92 s/c=0.88 id=30% cov=45%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RQIKARDLWRHILEAQSETGFPYILYKDNSNIKSN-QKNLGTIRSSNLCAEIIQYS--------DEHETAVCNLASICLPMFietnnnvkiYNFDKLGKVCRVAVRNLDKIIDRNYYPTEKTKRSNLRHRPMGIGAQGLADVYNIMGFGFSTHSAYELNKKIFETIYFACIDESKELAKKFGQYSTFKGSPASQGQLQFHMWGFNEDQLL---MGFDWKTLISEVKKYGLRNSLLTALMPTASTSQIMGNSECIEPYMSNIFKRSTLAGEFIVINKhlmkdlihlnlwnddmrkriiiengsvqnielIPEKLKNVYETAFETK-QMHIVRQSADRGIFIDQSQSLNLFMAEP-------DFDVLTSALFESHDIGNKTgMYYYRSLPAINPISFGID--IEDIKRLSG----
>UniRef50_Q19CR5(27-568:570) Ribonucleotide reductase A subunit n=3 Tax=unclassified T4-like viruses RepID=Q19CR5_9CAUD  E=2e-84 s/c=0.58 id=24% cov=62%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------FRRVASTLA---KHDIRPEAEERYFDLLWSGKLAMATPVFCNTGTDRGMPVSCAGSYVGDSVLDFYEGQTEVAMLAKNGFGTASYLGDIRPRGSDISTSHNKADGLVPVFDNFVNTKTKVAAAG-RRGEWAGYVDFSHGD------------------------------FWEL----QGYVLKNPASA---HVGWVFEKEDYEKL---LARDPEYMAR-------WNELLYMRARTGKGYMWKNWIANDLAPqaIKNSGIRIRSSQLCTEIALPS--------DDMHTFTCILSSLNLARWDEIS--AEDIKWAVRFLDSVCSeflekakkLPYDTLHKAIRFTEKARALGLGTLGFHTYLQMNDTAFESGAAHILNNSIYSQIKVYAEAASRELAEEHGEPEWCVGT--------------------------------------GMRNATLITIAPNMSSALLAgGVSQGVEPLVCNSFIQQSNAGDFVRSNPVLakvlsdrlsdkeikdlmeniatyhngsvqhldiltDHEKMVFKTAYEI-DQHAIIRLASARQRHIDQAQSINLFFAADEKESVVAS---VHKAFMD--DPRLKSLYYLRSERGVKAS-------TGEVECLAC----
>UniRef50_C9RBG7(18-289:955) Ribonucleoside-diphosphate reductase n=1 Tax=Ammonifex degensii KC4 RepID=C9RBG7_AMMDK  E=8e-78 s/c=1.08 id=23% cov=34%
-----------------------------------------------------------------------------------------------------------------------------------------------------ILEGRYLKRDEA-GNVVETPEEMFWRVARAVAEAEARFGAsaqevEEWARRFFELMASLDFLPNSPTLINAGRELGQLAACFVLPIEDSIESIFETLKYAALIHKSGGGTGFDFSRLRPKGDPVRSTGGVASGPVSFMRIFNAATEEIKQGGVRRGANMGILRADHPDIMEFVACKEEEGA----FRNFNISVAVTDAFFETLARSGEWELVFRGK----------------------------VYRRLPARELFDWIVQHAHANGEPGLLFLDAINRANPT-PALGRIEATNPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6IYQ9(29-302:1191) Ribonucleoside-diphosphate reductase n=1 Tax=Rhodospirillum centenum SW RepID=B6IYQ9_RHOCS  E=1e-73 s/c=1.03 id=20% cov=31%
---------------------------------------------------------------------------------------------------------------------------------------------------------KYRLKAPDGAPVDATVADTWTRVARALAAPER--DPAAWEERFRSALEGFRFLPAGRILAGAGTRRTvTLFNCFVMgTVPDDMGGIFAHLREAALTLQQGGGIGYDFSTLRPKGAPVAGVGADASGPVSFMDVWDSMCRTIMSAGSRRGAMMATLRCDHPDIELFIDAKREPG----RLRNFNLSVLATDDFMAAVREDRPWPLRF-------------DGRVF---------------RTVPARALWDRIMRATYDYAEPGVIFIDRINEQNN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0MFS7(88-399:1354) Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MFS7_RHOM4  E=2e-45 s/c=0.60 id=19% cov=25%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RPQASACFIISVEDSIDDIWQLMAESARLFKFGSGVGADWSKLRSTKEKLSG-GGRPSGPVSFMRVQDATGATIKSGGKtRRAAIMQTLKVWHPDIMEFVTAKakeekkawalieqgydgsfNGEAYSSVAFQNVNQSVRVTDEFMEAVLARRKFPL-------------------------KAVTTGKVI-EEIDAYELLYKVAEGTWICGDPGLQYEDTIQRWHTCK-NSGPINSSNPC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3UXH6(519-1141:1180) Ribonucleotide reductase n=7 Tax=Murid herpesvirus 1 RepID=B3UXH6_MUHV1  E=8e-54 s/c=0.34 id=21% cov=50%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYFDIWSVDALKIFSFILDVGREYEGL--ISFAVNTPRIFWDRYLDssgDKMWLMFARREAAALCGL---DLKSFRNVYEKMERDGRSAITVSP----WWAVCQldACVARGNTAVVF--PHNVKSMIPENIGRpavcgpgvsvvsggFVGCTPIHELCINLENCVLEGAAVESSVDVVLG---LGCRFSFKALESLVRDAVVLGNLLIDMTvRTNAYGAGKLLTLYRDLHIGVVGFHAVVNRLGQKFADMESYDLNQRIAEFIYYTAVRASVDLCMAGAdPFPKFPKSLYAAGRFYPDLFDDDERGPRRMTKEFL-EKLREDVVKHGIRNASFITGCSADEAANLAGTTPGFWPRRDNVFLEQtplmmtptkdqmldecvrsvkiephrlheedlsclgenrpvelpVLNSRLRQIskesatvavrrgrsAPFYDDSDDEdevacSETGWTVST-DAVIKMCVDRQPFVDHAQSL------------------------------------------------------------------
>UniRef50_Q3B5C1(831-1277:1521) Ribonucleotide reductase family protein n=9 Tax=Bacteria RepID=Q3B5C1_PELLD  E=3e-50 s/c=0.45 id=23% cov=37%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNLASLNLIHFVDEEsghvkinELRHAAALWTVVLEISVLMAHFPSPDIARLSYEYRTLGLGFANLGTVLMVLGIPYDSPKALALAGAISAIITGQAYVTSAEISRDLGPFDGYQANskemlrvirnhrraarneseeeYEELSVKPRGIDSEYCPKELFEAAGSVWDEALQKGKKYGFRNAQVSVIAPTGTIGLVMDCdTTGIEPEFAIVKFKKLAGGGYFKIVNqsVHKALKRLGYAAQEIEeiekyckgsgslegcpsinsqwlmnrgfteekiallesnlaavfdirfafnkwilgeefcqslgfteaqlndpgfdmlqalgasaedaeaandficgtmtiegaphlklehlpvfdcasrcgqkglrfiNHMAHVRMMSSVQPFISGAISKTVNM------PATATTAEIGEVYLSGWQHMVKaiTVY----RDGSKLSQPLNISSYQD----------
>UniRef50_P52343(279-672:804) Ribonucleoside-diphosphate reductase large subunit-like protein U28 n=5 Tax=Human herpesvirus 6 RepID=RIR1_HHV6U  E=2e-45 s/c=0.47 id=20% cov=42%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVYVEVWHVSALMWLDLYEALPQTSRVT----FCLIIPGIFMDRYElKRAQWSLFHKNIAFELGKC---DEITFSTKYLEFERTTDHAKITMSS--FIEKICLCL-KGGRMGLIFRKNVYQYSMIPHV--PLYCGgdfldvlpvrdgiNTCMRMLLNVVHFLGDEVSDELTEEIDFVRLQC-KFFMFNELRRVVRKMVLVANAVID---YAVENKDflcEGIEDGRSLGICVTGLHSVFMTVGLSYAHPDARRLYRMICEHIYYTCVRTSVDCCMKGAePCNLFDRSKYALGMLYFDHFDNVECTLPEEL----WTTLRKDVLMHGVRNIHF-----TAGTAMqkefdIINSSESFWPMEDNKILRRS------------------------------------------------------------------------------------------------------------------
>UniRef50_O55567(10-203:222) P25 n=1 Tax=Leucania separata nuclear polyhedrosis virus RepID=O55567_NPVLS  E=1e-40 s/c=0.88 id=21% cov=24%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SCFLLTMEsDSIRGIYNTLNDCAMISKHGGGIGLNVNSVRGRNSKIKSTNGTASGLLPMLRVFNNMVRHVIKVASEKAPKQCTLNRGIGDIMDVLHMRRNIGSEDTKARDLMNALWVPDIFMKRVEENGIWSLMCPNECPKLNDTY---GDDFEYWYKHYEDKGQF-REQMPAVTLMRNIIEIQAETAH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7XXH5(167-591:661) Ribonucleoside-triphosphate reductase n=2 Tax=unclassified Siphoviridae RepID=A7XXH5_9CAUD  E=1e-34 s/c=0.35 id=18% cov=39%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNLNSVRPLGSPLKRFGGFASGPGPLEDFF--LNAAFILGGTKPEGWT---DVKALDVANLIG-RMVVAGGTRRSAQISLGDWDSKNFIAA-----------------------KTGNWWATAPWRAQSNNSVLFYAKPDRDTLLAFFDAVLQYGEPGF-----VNAQTALKRRED-FRGVNPCSEILLRNK------------GVCNLTTVVLPNHvrngkVDYALLEDTLRLLTRHA-IRITTAQFPdvLSEWQRVQDEDRLIGVSFTGLDDFIHLTGL--DNDALAKVLAWMRSVVNDEAKRYSAELG------------------LPKPK--------------------------------LATTVKPEGTLSLLAGVSSGVHPAYAPYYIRRVR-----------------------------------------------------------------------------------------------------------------
>UniRef50_Q03PB4(229-748:749) Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase n=14 Tax=Lactobacillus RepID=RTPR_LACBA  E=4e-31 s/c=0.27 id=18% cov=52%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDISDIRPKNAPIHGFGGTASGPMPLVEMLfdinqilnnavgrqltavdctdmgNMIGKTVVAGNVRRSAE---LALGGAEDDAFITMKQDKDQLYHHRWASNNSVAVDSDF----------TDYAP-------------------------------------------IADSIQHNGEPGIVNLGLSRNYGRLidgrqEGIDEAVEGTNPCGEISLSNGEP------------CNLFEVFPSVAEEQgWQLEDAFGLGARYTKRV-TFSHYDWEVSRKAIQKNRRIGVSMSGIQDWILKT--------FKQRVVTGFEAKHDA----------ETG--KTFMQPIYNQA--AVNRFNALYQAVVKADQDYSDTLGCQPSIKH-------TTVKPSGTVAKLAGVSEGMHFHYARYLIQRIR---FQDSDPLLPALKASgYKVEPDVYSQNTMcvefpvkaahadepafasageVSMaeqfatQAFLQTyWSDNAVSCTVTFQPEEG-------QDISDLLLQ-YRHTIKStsllpysgadfkqapkepidaaTYDAKCQEITADVaekfaamtgnhdQKDIE-LVDQSDCESGACPI
>UniRef50_D0MVF9(208-595:662) Putative uncharacterized protein n=1 Tax=Phytophthora infestans T30-4 RepID=D0MVF9_PHYIN  E=9e-29 s/c=0.34 id=19% cov=42%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDYSLIRPAGAPIKGFGGIRSG-------------------------AGSLTALHVAIESILKplvGKLLTARGIVDIMN-QMGVCVVSGNVRRTAE----------IAFESAFGWTSNNSIFADIGMDYQP-----------------IAEQIVRNGEPGFAWLDNMrnfGRMNGIKDDRDRnASGGNPCLEQTLESYE------------MCCLVETFPYNHENLEDFLETLKHA-YMYAKTVTLGQTQWPRTNEVMKRNRRIGCSMSGIAQFISSRGL----NEFQRWCEAGYDRIQEVDKQISTRFA------------------------------------------IPRSIK--------TTSIKPSGTVSLLAGATPGMHYPESRFYIRRMHS---TFVVSIPVDVGEGVRTLSDVSAWEQF-ALASFLQRyWADNQVSCTVTFDP------------------------------------------------------------
>UniRef50_Q58N39(24-268:468) Ribonucleotide reductase domain-containing protein n=3 Tax=root RepID=Q58N39_BPPRP  E=8e-24 s/c=0.47 id=22% cov=31%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SCTIFVVEDSMEgkdGIEASWRFVSHALRFGAGVAVHLSKLRPAGTRTNKGPDTlvASGPVSFAKIYSTLNEILRRGGTyRNGACVLHLDINHPDIIDFVQVKR---------------------------QELPWV----KRCVDLTREQWSNTETRTKE----------------------AIIQGIAR-GDIWLNKIKYDNDGN-------RIY-SNVCLEVYLPSRGTCLLQHLN--MSACRIGDIREGMR---EGMSDLCKLHSR--TGIEESGEYLAPDID------RQVGFGLLGLANFLANNKITY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9V2J4(152-486:637) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V2J4_MONBE   E=2e-20 s/c=0.31 id=18% cov=37%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDYSQIRPKGSPLRTAGGRAPGP----DVLRSAFVAIEQRltSLSDGQPLASIDAH--DIM-------------CHAATAVASGGI--------RRSALISLFSPGDEAMLS---AKSGSWWESNSQRAMANNSVVLERERLshgefADLWTQI--RASGSGEPGVYFTH------------DRDWGTNPCCEIALEPFQF------------CNLTEINASIVRTQADLDELAHTAAFIGTLQASSTDFHFlrPQWRAVTEAAALVGVSMTGIAS----------------------------------------GT------------VLNKDLARAARTAVAANQRAAAQIGIQSA--------ARVTTVKPAGTTSLVLGTSSGVHAWHSPYYLRRVR-----------------------------------------------------------------------------------------------------------------
>UniRef50_Q2NME4(1-378:378) Ribonucleoside-diphosphate reductase large chain (Fragment) n=2 Tax=unclassified Iridovirus RepID=Q2NME4_IRV16  E=1e-16 s/c=0.24 id=22% cov=28%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEIISFLNTRRVSgfgGDYNYKLMNIHNGVNIPDNFMRKIwfistvapilkqengkrmkmleeaiktfQNSDKWVDENNLDLNKLTIENAQTYIKEMDKFDLTDPHNKEVKETISATELWERILVTRAECGEPYCHFIDTSNRKLPeFQKKLGLnIKQSNLCvvGEtlvltqngqfpikylvnqyvkvwngeewsevvvkktgfnqelvrvdfnngtsiICTPYHNFLSLEDdstiknlkricaqdlpcnfkvlyfyqnldfvttvkvtkithlsqradtycfseplnnagvfngiltgqcseiilptDENRTAVCCLASLNLDYYDNWCDNEQFYLDVATYLDNVlqyfIDNAPRSLKRAIYSAESERAIGIGVMGL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
