Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	K	D	A	L	N	N	V	H	I	T	D	E	Q	V	L	M	T	P	E	Q	L	K	A	A	F	P	L	S	L	Q	Q	E	A	Q	I	A	D	S	R	K	S	I	S	D	I	I	A	G	R	D	P	R	L	L	V	V	C	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?						?	?	?	?	?	?	?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	C	S	I	H	D	P	E	T	A	L	E	Y	A	R	R	F	K	A	L	A	A	E	V	S	D	S	L	Y	L	V	M	R	V	Y	F	E	K	P	R	T	T	V	G	W	K	G	L	I	N	D	P	H	M	D	G	S	F	D	V
Secondary structure
SS confidence
Disorder																									?																														?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	A	G	L	Q	I	A	R	K	L	L	L	E	L	V	N	M	G	L	P	L	A	T	E	A	L	D	P	N	S	P	Q	Y	L	G	D	L	F	S	W	S	A	I	G	A	R	T	T	E	S	Q	T	H	R	E	M	A	S	G	L
Secondary structure
SS confidence
Disorder																																																											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	M	P	V	G	F	K	N	G	T	D	G	S	L	A	T	A	I	N	A	M	R	A	A	A	Q	P	H	R	F	V	G	I	N	Q	A	G	Q	V	A	L	L	Q	T	Q	G	N	P	D	G	H	V	I	L	R	G	G	K	A	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	Y	S	P	A	D	V	A	Q	C	E	K	E	M	E	Q	A	G	L	R	P	S	L	M	V	D	C	S	H	G	N	S	N	K	D	Y	R	R	Q	P	A	V	A	E	S	V	V	A	Q	I	K	D	G	N	R	S	I	I	G	L
Secondary structure
SS confidence
Disorder																		?	?	?																																	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
Sequence		M	I	E	S	N	I	H	E	G	N	Q	S	S	E	Q	P	R	S	E	M	K	Y	G	V	S	V	T	D	A	C	I	S	W	E	M	T	D	A	L	L	R	E	I	H	Q	D	L	N	G	Q	L	T	A	R	V	A
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?	?	?	?		?																													?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1n8f chain A Region: 9 - 351 Aligned: 342 Modelled: 343 Confidence: 100.0% Identity: 54% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3tqk chain A Region: 10 - 352 Aligned: 340 Modelled: 343 Confidence: 100.0% Identity: 46% PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 Phyre2 PDB 1of8 chain A Region: 9 - 353 Aligned: 337 Modelled: 345 Confidence: 100.0% Identity: 52% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1ofa chain B Region: 9 - 353 Aligned: 335 Modelled: 345 Confidence: 100.0% Identity: 52% PDB header:lyase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: crystal structure of the tyrosine-regulated2 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase3 from saccharomyces cerevisiae in complex with4 phosphoenolpyruvate and cobalt(ii) Phyre2 PDB 1vr6 chain A domain 1 Region: 8 - 350 Aligned: 285 Modelled: 296 Confidence: 100.0% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1vs1 chain B Region: 43 - 343 Aligned: 242 Modelled: 257 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep Phyre2 PDB 1zco chain A Region: 44 - 345 Aligned: 242 Modelled: 271 Confidence: 100.0% Identity: 21% PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase Phyre2 PDB 2a21 chain A domain 1 Region: 53 - 346 Aligned: 245 Modelled: 264 Confidence: 100.0% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3nvt chain A Region: 44 - 346 Aligned: 244 Modelled: 285 Confidence: 100.0% Identity: 24% PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e Phyre2 PDB 3stg chain A Region: 44 - 348 Aligned: 247 Modelled: 261 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis Phyre2 PDB 3fs2 chain A Region: 44 - 345 Aligned: 241 Modelled: 272 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution Phyre2 PDB 1d9e chain A Region: 44 - 356 Aligned: 257 Modelled: 280 Confidence: 100.0% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 1o60 chain A Region: 44 - 349 Aligned: 255 Modelled: 281 Confidence: 100.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I DAHP synthetase Phyre2 PDB 3t4c chain D Region: 44 - 350 Aligned: 244 Modelled: 278 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria Phyre2 PDB 3sz8 chain D Region: 50 - 348 Aligned: 242 Modelled: 269 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei Phyre2 PDB 3pg8 chain B Region: 44 - 350 Aligned: 237 Modelled: 257 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima Phyre2 PDB 2zdr chain A domain 2 Region: 44 - 350 Aligned: 249 Modelled: 279 Confidence: 99.6% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: NeuB-like Phyre2 PDB 1vli chain A domain 2 Region: 44 - 350 Aligned: 251 Modelled: 275 Confidence: 99.4% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: NeuB-like Phyre2 PDB 1xuz chain A Region: 44 - 350 Aligned: 254 Modelled: 265 Confidence: 99.0% Identity: 14% PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol Phyre2 PDB 1vli chain A Region: 44 - 350 Aligned: 250 Modelled: 278 Confidence: 98.8% Identity: 15% PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution Phyre2 1 d1n8fa_ 2 c3tqkA_ 3 d1of8a_ 4 c1ofaB_ 5 d1vr6a1 6 c1vs1B_ 7 c1zcoA_ 8 d2a21a1 9 c3nvtA_ 10 c3stgA_ 11 c3fs2A_ 12 d1d9ea_ 13 d1o60a_ 14 c3t4cD_ 15 c3sz8D_ 16 c3pg8B_ 17 d2zdra2 18 d1vlia2 19 c1xuzA_ 20 c1vliA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1n8fa_ 100.0 54 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 2 c3tqkA_ 100.0 46 PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 3 d1of8a_ 100.0 52 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 4 c1ofaB_ 100.0 52 PDB header:lyase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: crystal structure of the tyrosine-regulated2 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase3 from saccharomyces cerevisiae in complex with4 phosphoenolpyruvate and cobalt(ii) 5 d1vr6a1 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 6 c1vs1B_ 100.0 23 PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep 7 c1zcoA_ 100.0 21 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase 8 d2a21a1 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 9 c3nvtA_ 100.0 24 PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e 10 c3stgA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis 11 c3fs2A_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution 12 d1d9ea_ 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 13 d1o60a_ 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 14 c3t4cD_ 100.0 18 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria 15 c3sz8D_ 100.0 14 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei 16 c3pg8B_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima 17 d2zdra2 99.6 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 18 d1vlia2 99.4 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 19 c1xuzA_ 99.0 14 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 20 c1vliA_ 98.8 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 21 d2b7oa1 not modelled 98.6 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class-II DAHP synthetase 22 c3g8rA_ not modelled 98.3 11 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 23 d1ad1a_ not modelled 94.6 13 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 24 d1ajza_ not modelled 92.7 21 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 25 c3eb2A_ not modelled 87.3 15 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 26 c2y5sA_ not modelled 86.8 24 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of burkholderia cenocepacia dihydropteroate2 synthase complexed with 7,8-dihydropteroate. 27 c2bmbA_ not modelled 82.7 14 PDB header:transferase Chain: A: PDB Molecule:folic acid synthesis protein fol1; PDBTitle: x-ray structure of the bifunctional 6-hydroxymethyl-7,8-2 dihydroxypterin pyrophosphokinase dihydropteroate synthase3 from saccharomyces cerevisiae 28 d1dxha1 not modelled 80.7 28 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 29 c2otcA_ not modelled 80.2 23 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine 30 c1ortD_ not modelled 78.6 29 PDB header:transferase Chain: D: PDB Molecule:ornithine transcarbamoylase; PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa 31 d1tx2a_ not modelled 77.8 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 32 c1tx2A_ not modelled 77.8 17 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 33 d1duvg1 not modelled 67.1 23 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 34 c3updA_ not modelled 63.6 22 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus 35 d1eyea_ not modelled 63.5 16 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 36 c3e5bB_ not modelled 62.7 17 PDB header:lyase Chain: B: PDB Molecule:isocitrate lyase; PDBTitle: 2.4 a crystal structure of isocitrate lyase from brucella2 melitensis 37 d1sq5a_ not modelled 60.3 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 38 d1f74a_ not modelled 57.6 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 39 c3fa4D_ not modelled 57.4 15 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 40 c2hjpA_ not modelled 56.9 15 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 41 c1a1sA_ not modelled 56.2 26 PDB header:transcarbamylase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus 42 d1vlva1 not modelled 56.1 22 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 43 d1o5ka_ not modelled 55.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 44 c2p2gD_ not modelled 54.1 29 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form 45 c2ehhE_ not modelled 53.5 18 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 46 c3d6nB_ not modelled 53.2 19 PDB header:hydrolase/transferase Chain: B: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 47 c1vlvA_ not modelled 52.6 21 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution 48 c3grfA_ not modelled 52.1 20 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia 49 c3si9B_ not modelled 51.3 16 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae 50 c3gd5D_ not modelled 50.8 23 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus 51 c3noeA_ not modelled 50.4 17 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 52 c2e3zB_ not modelled 47.4 27 PDB header:hydrolase Chain: B: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of intracellular family 1 beta-2 glucosidase bgl1a from the basidiomycete phanerochaete3 chrysosporium in substrate-free form 53 c3tqcB_ not modelled 46.7 11 PDB header:transferase Chain: B: PDB Molecule:pantothenate kinase; PDBTitle: structure of the pantothenate kinase (coaa) from coxiella burnetii 54 c3pueA_ not modelled 46.0 21 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution 55 c2v9dB_ not modelled 45.8 17 PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12 56 d1pvva1 not modelled 45.7 26 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 57 c2ze3A_ not modelled 44.2 15 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 58 c2w37A_ not modelled 42.8 24 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic; PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii 59 c3b4uB_ not modelled 42.5 16 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 60 d1muma_ not modelled 40.3 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 61 c3bi8A_ not modelled 39.9 13 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum 62 c1fvoB_ not modelled 39.7 24 PDB header:transferase Chain: B: PDB Molecule:ornithine transcarbamylase; PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate 63 c3igxA_ not modelled 39.2 19 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: 1.85 angstrom resolution crystal structure of transaldolase b (tala)2 from francisella tularensis. 64 c2vqqA_ not modelled 38.2 19 PDB header:hydrolase Chain: A: PDB Molecule:histone deacetylase 4; PDBTitle: structure of hdac4 catalytic domain (a double cysteine-to-2 alanine mutant) bound to a trifluoromethylketone inhbitor 65 c2ef0A_ not modelled 38.1 27 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus 66 c2ze5A_ not modelled 37.4 21 PDB header:transferase Chain: A: PDB Molecule:isopentenyl transferase; PDBTitle: crystal structure of adenosine phosphate-isopentenyltransferase 67 d2v3za1 not modelled 36.8 18 Fold:Ribonuclease H-like motif Superfamily:Creatinase/prolidase N-terminal domain Family:Creatinase/prolidase N-terminal domain 68 c2yxgD_ not modelled 36.8 23 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihyrodipicolinate synthase (dapa) 69 c3ptkB_ not modelled 36.7 23 PDB header:hydrolase Chain: B: PDB Molecule:beta-glucosidase os4bglu12; PDBTitle: the crystal structure of rice (oryza sativa l.) os4bglu12 70 d1igwa_ not modelled 36.4 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 71 c2qw5B_ not modelled 34.1 14 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution 72 d1pffa_ not modelled 34.0 18 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 73 c3g0sA_ not modelled 33.0 18 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 74 c3cprB_ not modelled 31.9 18 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 75 c3a8tA_ not modelled 31.7 26 PDB header:transferase Chain: A: PDB Molecule:adenylate isopentenyltransferase; PDBTitle: plant adenylate isopentenyltransferase in complex with atp 76 c3daqB_ not modelled 31.6 18 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 77 c3oixA_ not modelled 31.2 15 PDB header:oxidoreductase Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans 78 c2p2sA_ not modelled 30.7 19 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution 79 c1f9cA_ not modelled 29.8 14 PDB header:isomerase Chain: A: PDB Molecule:protein (muconate cycloisomerase i); PDBTitle: crystal structure of mle d178n variant 80 c3fluD_ not modelled 29.4 16 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 81 d2a6na1 not modelled 27.7 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 82 c3na8A_ not modelled 27.5 13 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa 83 c3ahyD_ not modelled 27.0 17 PDB header:hydrolase Chain: D: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of beta-glucosidase 2 from fungus trichoderma reesei2 in complex with tris 84 d1f05a_ not modelled 26.6 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 85 d2e1da1 not modelled 26.5 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 86 c2wamB_ not modelled 26.4 13 PDB header:unknown function Chain: B: PDB Molecule:conserved hypothetical alanine and leucine rich PDBTitle: crystal structure of mycobacterium tuberculosis unknown2 function protein rv2714 87 c2dzaA_ not modelled 25.8 16 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate 88 c3s5oA_ not modelled 25.7 13 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate 89 c2gqnB_ not modelled 25.3 18 PDB header:lyase Chain: B: PDB Molecule:cystathionine beta-lyase; PDBTitle: cystathionine beta-lyase (cbl) from escherichia coli in complex with2 n-hydrazinocarbonylmethyl-2-nitro-benzamide 90 d1e5ea_ not modelled 25.3 27 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 91 c3m16A_ not modelled 25.0 17 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: structure of a transaldolase from oleispira antarctica 92 d1piia2 not modelled 24.9 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 93 c2cb1A_ not modelled 24.5 20 PDB header:lyase Chain: A: PDB Molecule:o-acetyl homoserine sulfhydrylase; PDBTitle: crystal structure of o-actetyl homoserine sulfhydrylase2 from thermus thermophilus hb8,oah2. 94 d1tuga1 not modelled 24.1 18 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 95 c2nmpC_ not modelled 23.5 24 PDB header:lyase Chain: C: PDB Molecule:cystathionine gamma-lyase; PDBTitle: crystal structure of human cystathionine gamma lyase 96 d1n8pa_ not modelled 23.4 35 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 97 c3d3qB_ not modelled 23.3 36 PDB header:transferase Chain: B: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of trna delta(2)-isopentenylpyrophosphate2 transferase (se0981) from staphylococcus epidermidis.3 northeast structural genomics consortium target ser100 98 c3exaD_ not modelled 22.6 24 PDB header:transferase Chain: D: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: crystal structure of the full-length trna2 isopentenylpyrophosphate transferase (bh2366) from3 bacillus halodurans, northeast structural genomics4 consortium target bhr41. 99 c3gndC_ not modelled 22.2 17 PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate 100 d1qgna_ not modelled 22.1 29 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Cystathionine synthase-like 101 c2rgwD_ not modelled 22.0 13 PDB header:transferase Chain: D: PDB Molecule:aspartate carbamoyltransferase; PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase 102 d1ujqa_ not modelled 21.9 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 103 c3tr9A_ not modelled 21.6 15 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii 104 d2auwa1 not modelled 21.4 63 Fold:lambda repressor-like DNA-binding domains Superfamily:lambda repressor-like DNA-binding domains Family:NE0471 C-terminal domain-like 105 c2jf7B_ not modelled 21.2 18 PDB header:hydrolase Chain: B: PDB Molecule:strictosidine-o-beta-d-glucosidase; PDBTitle: structure of strictosidine glucosidase 106 c2vc6A_ not modelled 20.2 19 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0