Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	L	I	E	K	H	V	S	F	G	G	W	Q	N	M	Y	R	H	Y	S	Q	S	L	K	C	E	M	N	V	G	V	Y	L	P	P	K	A	A	N	E	K	L	P	V	L	Y	W	L	S	G	L	T	C	N	E	Q	N	F	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	K	S	G	M	Q	R	Y	A	A	E	H	N	I	I	V	V	A	P	D	T	S	P	R	G	S	H	V	A	D	A	D	R	Y	D	L	G	Q	G	A	G	F	Y	L	N	A	T	Q	A	P	W	N	E	H	Y	K	M	Y	D	Y
Secondary structure
SS confidence
Disorder																																																		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	R	N	E	L	P	D	L	V	M	H	H	F	P	A	T	A	K	K	S	I	S	G	H	S	M	G	G	L	G	A	L	V	L	A	L	R	N	P	D	E	Y	V	S	V	S	A	F	S	P	I	V	S	P	S	Q	V	P	W	G
Secondary structure
SS confidence
Disorder																																																									?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	Q	A	F	A	A	Y	L	A	E	N	K	D	A	W	L	D	Y	D	P	V	S	L	I	S	Q	G	Q	R	V	A	E	I	M	V	D	Q	G	L	S	D	D	F	Y	A	E	Q	L	R	T	P	N	L	E	K	I	C	Q	E	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
Sequence		N	I	K	T	L	I	R	Y	H	E	G	Y	D	H	S	Y	Y	F	V	S	S	F	I	G	E	H	I	A	Y	H	A	N	K	L	N	M	R
Secondary structure
SS confidence
Disorder																																			?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3i6y chain A Region: 1 - 275 Aligned: 275 Modelled: 275 Confidence: 100.0% Identity: 55% PDB header:hydrolase Chain: A: PDB Molecule:esterase apc40077; PDBTitle: structure of an esterase from the oil-degrading bacterium oleispira2 antarctica Phyre2 PDB 3e4d chain D Region: 3 - 275 Aligned: 273 Modelled: 273 Confidence: 100.0% Identity: 44% PDB header:hydrolase Chain: D: PDB Molecule:esterase d; PDBTitle: structural and kinetic study of an s-formylglutathione2 hydrolase from agrobacterium tumefaciens Phyre2 PDB 3ls2 chain D Region: 1 - 275 Aligned: 275 Modelled: 275 Confidence: 100.0% Identity: 50% PDB header:hydrolase Chain: D: PDB Molecule:s-formylglutathione hydrolase; PDBTitle: crystal structure of an s-formylglutathione hydrolase from2 pseudoalteromonas haloplanktis tac125 Phyre2 PDB 1pv1 chain A Region: 1 - 276 Aligned: 274 Modelled: 276 Confidence: 100.0% Identity: 43% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Hypothetical esterase YJL068C Phyre2 PDB 3fcx chain A Region: 1 - 275 Aligned: 263 Modelled: 275 Confidence: 100.0% Identity: 48% PDB header:hydrolase Chain: A: PDB Molecule:s-formylglutathione hydrolase; PDBTitle: crystal structure of human esterase d Phyre2 PDB 1dqz chain A Region: 9 - 275 Aligned: 249 Modelled: 249 Confidence: 100.0% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Mycobacterial antigens Phyre2 PDB 1sfr chain A Region: 6 - 276 Aligned: 255 Modelled: 259 Confidence: 100.0% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Mycobacterial antigens Phyre2 PDB 1f0n chain A Region: 10 - 275 Aligned: 250 Modelled: 254 Confidence: 100.0% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Mycobacterial antigens Phyre2 PDB 2ecf chain A Region: 13 - 275 Aligned: 246 Modelled: 249 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase iv; PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia Phyre2 PDB 1jjf chain A Region: 10 - 272 Aligned: 220 Modelled: 223 Confidence: 100.0% Identity: 19% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Carboxylesterase Phyre2 PDB 1z68 chain A Region: 2 - 275 Aligned: 258 Modelled: 260 Confidence: 100.0% Identity: 11% PDB header:lyase Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit; PDBTitle: crystal structure of human fibroblast activation protein alpha Phyre2 PDB 2eep chain A Region: 12 - 274 Aligned: 246 Modelled: 249 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative; PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor Phyre2 PDB 3azq chain A Region: 12 - 277 Aligned: 246 Modelled: 252 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase; PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg Phyre2 PDB 2qtb chain B Region: 13 - 276 Aligned: 248 Modelled: 250 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor Phyre2 PDB 3c8d chain A domain 2 Region: 10 - 274 Aligned: 225 Modelled: 233 Confidence: 100.0% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Carboxylesterase Phyre2 PDB 2uz0 chain B Region: 11 - 276 Aligned: 234 Modelled: 244 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:tributyrin esterase; PDBTitle: the crystal crystal structure of the esta protein, a2 virulence factor esta protein from streptococcus pneumonia Phyre2 PDB 3c8d chain A Region: 11 - 274 Aligned: 223 Modelled: 224 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:enterochelin esterase; PDBTitle: crystal structure of the enterobactin esterase fes from2 shigella flexneri in the presence of 2,3-di-hydroxy-n-3 benzoyl-glycine Phyre2 PDB 2g5t chain A Region: 3 - 275 Aligned: 257 Modelled: 259 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag Phyre2 PDB 1r88 chain A Region: 12 - 274 Aligned: 238 Modelled: 238 Confidence: 100.0% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Mycobacterial antigens Phyre2 PDB 1qfm chain A Region: 13 - 276 Aligned: 248 Modelled: 250 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:protein (prolyl oligopeptidase); PDBTitle: prolyl oligopeptidase from porcine muscle Phyre2 1 c3i6yA_ 2 c3e4dD_ 3 c3ls2D_ 4 d1pv1a_ 5 c3fcxA_ 6 d1dqza_ 7 d1sfra_ 8 d1f0na_ 9 c2ecfA_ 10 d1jjfa_ 11 c1z68A_ 12 c2eepA_ 13 c3azqA_ 14 c2qtbB_ 15 d3c8da2 16 c2uz0B_ 17 c3c8dA_ 18 c2g5tA_ 19 d1r88a_ 20 c1qfmA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3i6yA_ 100.0 55 PDB header:hydrolase Chain: A: PDB Molecule:esterase apc40077; PDBTitle: structure of an esterase from the oil-degrading bacterium oleispira2 antarctica 2 c3e4dD_ 100.0 44 PDB header:hydrolase Chain: D: PDB Molecule:esterase d; PDBTitle: structural and kinetic study of an s-formylglutathione2 hydrolase from agrobacterium tumefaciens 3 c3ls2D_ 100.0 50 PDB header:hydrolase Chain: D: PDB Molecule:s-formylglutathione hydrolase; PDBTitle: crystal structure of an s-formylglutathione hydrolase from2 pseudoalteromonas haloplanktis tac125 4 d1pv1a_ 100.0 43 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical esterase YJL068C 5 c3fcxA_ 100.0 48 PDB header:hydrolase Chain: A: PDB Molecule:s-formylglutathione hydrolase; PDBTitle: crystal structure of human esterase d 6 d1dqza_ 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Mycobacterial antigens 7 d1sfra_ 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Mycobacterial antigens 8 d1f0na_ 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Mycobacterial antigens 9 c2ecfA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase iv; PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia 10 d1jjfa_ 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 11 c1z68A_ 100.0 11 PDB header:lyase Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit; PDBTitle: crystal structure of human fibroblast activation protein alpha 12 c2eepA_ 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative; PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor 13 c3azqA_ 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase; PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg 14 c2qtbB_ 100.0 14 PDB header:hydrolase Chain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor 15 d3c8da2 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 16 c2uz0B_ 100.0 23 PDB header:hydrolase Chain: B: PDB Molecule:tributyrin esterase; PDBTitle: the crystal crystal structure of the esta protein, a2 virulence factor esta protein from streptococcus pneumonia 17 c3c8dA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:enterochelin esterase; PDBTitle: crystal structure of the enterobactin esterase fes from2 shigella flexneri in the presence of 2,3-di-hydroxy-n-3 benzoyl-glycine 18 c2g5tA_ 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag 19 d1r88a_ 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Mycobacterial antigens 20 c1qfmA_ 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:protein (prolyl oligopeptidase); PDBTitle: prolyl oligopeptidase from porcine muscle 21 c2hu7A_ not modelled 100.0 11 PDB header:hydrolase Chain: A: PDB Molecule:acylamino-acid-releasing enzyme; PDBTitle: binding of inhibitors by acylaminoacyl peptidase 22 c2bklB_ not modelled 100.0 14 PDB header:hydrolase Chain: B: PDB Molecule:prolyl endopeptidase; PDBTitle: structural and mechanistic analysis of two prolyl2 endopeptidases: role of inter-domain dynamics in3 catalysis and specificity 23 c1wb4A_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:endo-1,4-beta-xylanase y; PDBTitle: s954a mutant of the feruloyl esterase module from2 clostridium thermocellum complexed with sinapinate 24 d1wb4a1 not modelled 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 25 c3doiA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:esterase; PDBTitle: crystal structure of a thermostable esterase complex with2 paraoxon 26 c1xfdD_ not modelled 100.0 11 PDB header:membrane protein Chain: D: PDB Molecule:dipeptidyl aminopeptidase-like protein 6; PDBTitle: structure of a human a-type potassium channel accelerating factor2 dppx, a member of the dipeptidyl aminopeptidase family 27 c3iumA_ not modelled 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:prolyl endopeptidase; PDBTitle: appep_wtx opened state 28 c2xe4A_ not modelled 100.0 13 PDB header:hydrolase/inhibitor Chain: A: PDB Molecule:oligopeptidase b; PDBTitle: structure of oligopeptidase b from leishmania major 29 c2qm0B_ not modelled 100.0 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:bes; PDBTitle: crystal structure of bes protein from bacillus cereus 30 c1yr2A_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:prolyl oligopeptidase; PDBTitle: structural and mechanistic analysis of two prolyl endopeptidases: role2 of inter-domain dynamics in catalysis and specificity 31 c3gffA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:iroe-like serine hydrolase; PDBTitle: crystal structure of iroe-like serine hydrolase (np_718593.1) from2 shewanella oneidensis at 2.12 a resolution 32 d1qfma2 not modelled 100.0 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Prolyl oligopeptidase, C-terminal domain 33 c3bxpA_ not modelled 100.0 9 PDB header:hydrolase Chain: A: PDB Molecule:putative lipase/esterase; PDBTitle: crystal structure of a putative carboxylesterase (lp_2923) from2 lactobacillus plantarum wcfs1 at 1.70 a resolution 34 d2gzsa1 not modelled 100.0 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:IroE-like 35 d1orva2 not modelled 100.0 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:DPP6 catalytic domain-like 36 d2bgra2 not modelled 100.0 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:DPP6 catalytic domain-like 37 d1xfda2 not modelled 100.0 11 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:DPP6 catalytic domain-like 38 c2o7vA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:cxe carboxylesterase; PDBTitle: carboxylesterase aecxe1 from actinidia eriantha covalently inhibited2 by paraoxon 39 c3bjrA_ not modelled 100.0 10 PDB header:hydrolase Chain: A: PDB Molecule:putative carboxylesterase; PDBTitle: crystal structure of a putative carboxylesterase (lp_1002) from2 lactobacillus plantarum wcfs1 at 2.09 a resolution 40 c3ga7A_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:acetyl esterase; PDBTitle: 1.55 angstrom crystal structure of an acetyl esterase from salmonella2 typhimurium 41 c2zshA_ not modelled 99.9 13 PDB header:hormone receptor Chain: A: PDB Molecule:probable gibberellin receptor gid1l1; PDBTitle: structural basis of gibberellin(ga3)-induced della2 recognition by the gibberellin receptor 42 d2hu7a2 not modelled 99.9 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acylamino-acid-releasing enzyme, C-terminal donain 43 c3ed1E_ not modelled 99.9 16 PDB header:hydrolase receptor Chain: E: PDB Molecule:gibberellin receptor gid1; PDBTitle: crystal structure of rice gid1 complexed with ga3 44 c3k2iA_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4; PDBTitle: human acyl-coenzyme a thioesterase 4 45 d1jkma_ not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 46 c3hlkB_ not modelled 99.9 15 PDB header:hydrolase Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial; PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2) 47 c3hxkB_ not modelled 99.9 9 PDB header:hydrolase Chain: B: PDB Molecule:sugar hydrolase; PDBTitle: crystal structure of a sugar hydrolase (yeeb) from2 lactococcus lactis, northeast structural genomics3 consortium target kr108 48 d1lzla_ not modelled 99.9 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 49 d2h1ia1 not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 50 c3d0kA_ not modelled 99.9 12 PDB header:hydrolase Chain: A: PDB Molecule:putative poly(3-hydroxybutyrate) depolymerase lpqc; PDBTitle: crystal structure of the lpqc, poly(3-hydroxybutyrate) depolymerase2 from bordetella parapertussis 51 c3u0vA_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:lysophospholipase-like protein 1; PDBTitle: crystal structure analysis of human lyplal1 52 c2h1iA_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:carboxylesterase; PDBTitle: crystal structure of the bacillus cereus carboxylesterase 53 c2o2gA_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:dienelactone hydrolase; PDBTitle: crystal structure of dienelactone hydrolase (yp_324580.1) from2 anabaena variabilis atcc 29413 at 1.92 a resolution 54 c2c7bA_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:carboxylesterase; PDBTitle: the crystal structure of este1, a new thermophilic and2 thermostable carboxylesterase cloned from a metagenomic3 library 55 c3d7rB_ not modelled 99.9 12 PDB header:hydrolase Chain: B: PDB Molecule:esterase; PDBTitle: crystal structure of a putative esterase from staphylococcus aureus 56 c3og9A_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:protein yahd a copper inducible hydrolase; PDBTitle: structure of yahd with malic acid 57 d3b5ea1 not modelled 99.9 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 58 c3fakA_ not modelled 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:esterase/lipase; PDBTitle: structural and functional analysis of a hormone-sensitive2 lipase like este5 from a metagenome library 59 c3fnbB_ not modelled 99.9 12 PDB header:hydrolase Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737; PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159 60 d1fj2a_ not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 61 c2wirB_ not modelled 99.9 14 PDB header:hydrolase Chain: B: PDB Molecule:alpha/beta hydrolase fold-3 domain protein; PDBTitle: hyperthermophilic esterase from the archeon pyrobaculum2 calidifontis 62 c2qruA_ not modelled 99.9 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis 63 d2jbwa1 not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:2,6-dihydropseudooxynicotine hydrolase-like 64 c3dnmA_ not modelled 99.9 11 PDB header:hydrolase Chain: A: PDB Molecule:esterase/lipase; PDBTitle: crystal structure hormone-sensitive lipase from a2 metagenome library 65 c3ksrA_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:putative serine hydrolase; PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution 66 d1u4na_ not modelled 99.9 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 67 c2jbwB_ not modelled 99.9 13 PDB header:hydrolase Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase; PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase. 68 d1jjia_ not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 69 d1l7aa_ not modelled 99.9 11 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetyl xylan esterase-like 70 c2wtmC_ not modelled 99.9 16 PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus 71 c3f67A_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:putative dienelactone hydrolase; PDBTitle: crystal structure of putative dienelactone hydrolase from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 72 d1auoa_ not modelled 99.9 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 73 c3qh4A_ not modelled 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:esterase lipw; PDBTitle: crystal structure of esterase lipw from mycobacterium marinum 74 d1ju3a2 not modelled 99.9 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:PepX catalytic domain-like 75 c3cn9B_ not modelled 99.9 13 PDB header:hydrolase Chain: B: PDB Molecule:carboxylesterase; PDBTitle: crystal structure analysis of the carboxylesterase pa3859 from2 pseudomonas aeruginosa pao1- orthorhombic crystal form 76 c3aikB_ not modelled 99.9 10 PDB header:hydrolase Chain: B: PDB Molecule:303aa long hypothetical esterase; PDBTitle: crystal structure of a hsl-like carboxylesterase from sulfolobus2 tokodaii 77 c2r8bA_ not modelled 99.9 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu2452; PDBTitle: the crystal structure of the protein atu2452 of unknown function from2 agrobacterium tumefaciens str. c58 78 c3h2iA_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:esterase; PDBTitle: crystal structure of n228w mutant of the rice cell wall2 degrading esterase lipa from xanthomonas oryzae 79 d1vlqa_ not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetyl xylan esterase-like 80 c3mveB_ not modelled 99.9 10 PDB header:lyase Chain: B: PDB Molecule:upf0255 protein vv1_0328; PDBTitle: crystal structure of a novel pyruvate decarboxylase 81 c2hdwB_ not modelled 99.9 13 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein pa2218; PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa 82 d1ufoa_ not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical protein TT1662 83 c1l7qA_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:cocaine esterase; PDBTitle: ser117ala mutant of bacterial cocaine esterase coce 84 d2r8ba1 not modelled 99.9 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 85 c2b9vB_ not modelled 99.9 13 PDB header:hydrolase Chain: B: PDB Molecule:alpha-amino acid ester hydrolase; PDBTitle: acetobacter turbidans alpha-amino acid ester hydrolase 86 c3h04A_ not modelled 99.9 7 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50 87 c2i3dA_ not modelled 99.9 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein atu1826; PDBTitle: crystal structure of protein of unknown function atu1826, a putative2 alpha/beta hydrolase from agrobacterium tumefaciens 88 d2i3da1 not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Atu1826-like 89 d1vkha_ not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Putative serine hydrolase Ydr428c 90 d2b9va2 not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:PepX catalytic domain-like 91 d2pbla1 not modelled 99.8 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 92 d1jfra_ not modelled 99.8 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Lipase 93 c2fx5A_ not modelled 99.8 18 PDB header:hydrolase Chain: A: PDB Molecule:lipase; PDBTitle: pseudomonas mendocina lipase 94 d1dina_ not modelled 99.8 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Dienelactone hydrolase 95 c2veoA_ not modelled 99.8 14 PDB header:hydrolase Chain: A: PDB Molecule:lipase a; PDBTitle: x-ray structure of candida antarctica lipase a in its2 closed state. 96 d2fuka1 not modelled 99.8 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Atu1826-like 97 c3fcyB_ not modelled 99.8 14 PDB header:hydrolase Chain: B: PDB Molecule:xylan esterase 1; PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485 98 d1mpxa2 not modelled 99.8 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:PepX catalytic domain-like 99 c3llcA_ not modelled 99.8 19 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution 100 d1hlga_ not modelled 99.8 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 101 c1mpxB_ not modelled 99.8 14 PDB header:hydrolase Chain: B: PDB Molecule:alpha-amino acid ester hydrolase; PDBTitle: alpha-amino acid ester hydrolase labeled with selenomethionine 102 c3trdA_ not modelled 99.8 15 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase; PDBTitle: structure of an alpha-beta serine hydrolase homologue from coxiella2 burnetii 103 c3qm1A_ not modelled 99.8 16 PDB header:hydrolase Chain: A: PDB Molecule:cinnamoyl esterase; PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii 104 c3ib3A_ not modelled 99.8 9 PDB header:hydrolase Chain: A: PDB Molecule:coce/nond family hydrolase; PDBTitle: crystal structure of sacol2612 - coce/nond family hydrolase from2 staphylococcus aureus 105 d1k8qa_ not modelled 99.7 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 106 c1ycdA_ not modelled 99.7 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical 27.3 kda protein in aap1-smf2 PDBTitle: crystal structure of yeast fsh1/yhr049w, a member of the2 serine hydrolase family 107 d2b61a1 not modelled 99.7 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 108 c3jw8A_ not modelled 99.7 16 PDB header:hydrolase Chain: A: PDB Molecule:mgll protein; PDBTitle: crystal structure of human mono-glyceride lipase 109 c3hjuB_ not modelled 99.7 15 PDB header:hydrolase Chain: B: PDB Molecule:monoglyceride lipase; PDBTitle: crystal structure of human monoglyceride lipase 110 c3dyvA_ not modelled 99.7 16 PDB header:hydrolase Chain: A: PDB Molecule:esterase d; PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism 111 d1uxoa_ not modelled 99.7 11 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:YdeN-like 112 c3i1iA_ not modelled 99.7 11 PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis 113 c3g8yA_ not modelled 99.7 11 PDB header:hydrolase Chain: A: PDB Molecule:susd/ragb-associated esterase-like protein; PDBTitle: crystal structure of a putative hydrolase (bvu_4111) from bacteroides2 vulgatus atcc 8482 at 1.90 a resolution 114 d1lnsa3 not modelled 99.7 22 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:PepX catalytic domain-like 115 c2vavL_ not modelled 99.7 12 PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) 116 c2q0xA_ not modelled 99.7 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: alpha/beta hydrolase fold protein of unknown function 117 d2vata1 not modelled 99.7 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 118 d1qe3a_ not modelled 99.7 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetylcholinesterase-like 119 c2qjwA_ not modelled 99.7 13 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein xcc1541; PDBTitle: crystal structure of a putative hydrolase of the alpha/beta2 superfamily (xcc1541) from xanthomonas campestris pv. campestris at3 1.35 a resolution 120 d2pl5a1 not modelled 99.7 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0