Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	V	T	L	T	F	N	E	Q	R	R	A	A	Y	R	Q	Q	G	L	W	G	D	A	S	L	A	D	Y	W	Q	Q	T	A	R	A	M	P	D	K	I	A	V	V	D	N	H	G	A	S	Y	T	Y	S	A	L	D	H	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	C	L	A	N	W	M	L	A	K	G	I	E	S	G	D	R	I	A	F	Q	L	P	G	W	C	E	F	T	V	I	Y	L	A	C	L	K	I	G	A	V	S	V	P	L	L	P	S	W	R	E	A	E	L	V	W	V	L	N	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		C	Q	A	K	M	F	F	A	P	T	L	F	K	Q	T	R	P	V	D	L	I	L	P	L	Q	N	Q	L	P	Q	L	Q	Q	I	V	G	V	D	K	L	A	P	A	T	S	S	L	S	L	S	Q	I	I	A	D	N	T	S	L	T
Secondary structure
SS confidence
Disorder																																																							?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	A	I	T	T	H	G	D	E	L	A	A	V	L	F	T	S	G	T	E	G	L	P	K	G	V	M	L	T	H	N	N	I	L	A	S	E	R	A	Y	C	A	R	L	N	L	T	W	Q	D	V	F	M	M	P	A	P	L	G	H
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	T	G	F	L	H	G	V	T	A	P	F	L	I	G	A	R	S	V	L	L	D	I	F	T	P	D	A	C	L	A	L	L	E	Q	Q	R	C	T	C	M	L	G	A	T	P	F	V	Y	D	L	L	N	V	L	E	K	Q	P	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	L	S	A	L	R	F	F	L	C	G	G	T	T	I	P	K	K	V	A	R	E	C	Q	Q	R	G	I	K	L	L	S	V	Y	G	S	T	E	S	S	P	H	A	V	V	N	L	D	D	P	L	S	R	F	M	H	T	D	G	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	A	A	G	V	E	I	K	V	V	D	D	A	R	K	T	L	P	P	G	C	E	G	E	E	A	S	R	G	P	N	V	F	M	G	Y	F	D	E	P	E	L	T	A	R	A	L	D	E	E	G	W	Y	Y	S	G	D	L	C	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		M	D	E	A	G	Y	I	K	I	T	G	R	K	K	D	I	I	V	R	G	G	E	N	I	S	S	R	E	V	E	D	I	L	L	Q	H	P	K	I	H	D	A	C	V	V	A	M	S	D	E	R	L	G	E	R	S	C	A	Y	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		V	L	K	A	P	H	H	S	L	S	L	E	E	V	V	A	F	F	S	R	K	R	V	A	K	Y	K	Y	P	E	H	I	V	V	I	E	K	L	P	R	T	T	S	G	K	I	Q	K	F	L	L	R	K	D	I	M	R	R	L	T
Secondary structure
SS confidence
Disorder										?
Disorder confidence
		.	.	.	.	.	.	.	.
Sequence		Q	D	V	C	E	E	I	E
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1pg4 chain A Region: 20 - 547 Aligned: 528 Modelled: 528 Confidence: 100.0% Identity: 23% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 1mdb chain A Region: 7 - 541 Aligned: 526 Modelled: 535 Confidence: 100.0% Identity: 29% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 1ry2 chain A Region: 25 - 548 Aligned: 520 Modelled: 524 Confidence: 100.0% Identity: 22% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 3e7w chain A Region: 24 - 539 Aligned: 493 Modelled: 494 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains Phyre2 PDB 2vsq chain A Region: 17 - 533 Aligned: 488 Modelled: 497 Confidence: 100.0% Identity: 24% PDB header:ligase Chain: A: PDB Molecule:surfactin synthetase subunit 3; PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module Phyre2 PDB 3cw9 chain A domain 1 Region: 24 - 535 Aligned: 495 Modelled: 498 Confidence: 100.0% Identity: 21% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 3ni2 chain A Region: 22 - 534 Aligned: 502 Modelled: 513 Confidence: 100.0% Identity: 26% PDB header:ligase Chain: A: PDB Molecule:4-coumarate:coa ligase; PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase Phyre2 PDB 3etc chain B Region: 25 - 520 Aligned: 493 Modelled: 496 Confidence: 100.0% Identity: 24% PDB header:ligase Chain: B: PDB Molecule:amp-binding protein; PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298 Phyre2 PDB 3eyn chain B Region: 26 - 535 Aligned: 498 Modelled: 505 Confidence: 100.0% Identity: 25% PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa Phyre2 PDB 1amu chain A Region: 17 - 533 Aligned: 483 Modelled: 497 Confidence: 100.0% Identity: 21% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 2d1t chain A Region: 22 - 539 Aligned: 508 Modelled: 513 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:luciferin 4-monooxygenase; PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue Phyre2 PDB 1amu chain B Region: 9 - 533 Aligned: 490 Modelled: 504 Confidence: 100.0% Identity: 22% PDB header:peptide synthetase Chain: B: PDB Molecule:gramicidin synthetase 1; PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine Phyre2 PDB 3gqw chain B Region: 25 - 543 Aligned: 495 Modelled: 501 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: B: PDB Molecule:fatty acid amp ligase; PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound Phyre2 PDB 3dhv chain A Region: 26 - 537 Aligned: 486 Modelled: 492 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase; PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate Phyre2 PDB 3kxw chain A Region: 22 - 545 Aligned: 505 Modelled: 505 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:saframycin mx1 synthetase b; PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila Phyre2 PDB 3ite chain B Region: 24 - 532 Aligned: 482 Modelled: 492 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:sidn siderophore synthetase; PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase Phyre2 PDB 1lci chain A Region: 20 - 534 Aligned: 502 Modelled: 515 Confidence: 100.0% Identity: 23% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 3tsy chain A Region: 22 - 547 Aligned: 516 Modelled: 526 Confidence: 100.0% Identity: 22% PDB header:ligase, transferase Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein Phyre2 PDB 2v7b chain B Region: 25 - 533 Aligned: 484 Modelled: 492 Confidence: 100.0% Identity: 24% PDB header:ligase Chain: B: PDB Molecule:benzoate-coenzyme a ligase; PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400 Phyre2 PDB 3l8c chain A Region: 24 - 535 Aligned: 482 Modelled: 490 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: structure of probable d-alanine--poly(phosphoribitol) ligase2 subunit-1 from streptococcus pyogenes Phyre2 1 d1pg4a_ 2 d1mdba_ 3 d1ry2a_ 4 c3e7wA_ 5 c2vsqA_ 6 d3cw9a1 7 c3ni2A_ 8 c3etcB_ 9 c3eynB_ 10 d1amua_ 11 c2d1tA_ 12 c1amuB_ 13 c3gqwB_ 14 c3dhvA_ 15 c3kxwA_ 16 c3iteB_ 17 d1lcia_ 18 c3tsyA_ 19 c2v7bB_ 20 c3l8cA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1pg4a_ 100.0 23 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 2 d1mdba_ 100.0 29 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 3 d1ry2a_ 100.0 22 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 4 c3e7wA_ 100.0 19 PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains 5 c2vsqA_ 100.0 24 PDB header:ligase Chain: A: PDB Molecule:surfactin synthetase subunit 3; PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module 6 d3cw9a1 100.0 21 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 7 c3ni2A_ 100.0 26 PDB header:ligase Chain: A: PDB Molecule:4-coumarate:coa ligase; PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase 8 c3etcB_ 100.0 24 PDB header:ligase Chain: B: PDB Molecule:amp-binding protein; PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298 9 c3eynB_ 100.0 25 PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa 10 d1amua_ 100.0 21 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 11 c2d1tA_ 100.0 25 PDB header:oxidoreductase Chain: A: PDB Molecule:luciferin 4-monooxygenase; PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue 12 c1amuB_ 100.0 22 PDB header:peptide synthetase Chain: B: PDB Molecule:gramicidin synthetase 1; PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine 13 c3gqwB_ 100.0 22 PDB header:ligase Chain: B: PDB Molecule:fatty acid amp ligase; PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound 14 c3dhvA_ 100.0 22 PDB header:ligase Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase; PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate 15 c3kxwA_ 100.0 19 PDB header:ligase Chain: A: PDB Molecule:saframycin mx1 synthetase b; PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila 16 c3iteB_ 100.0 20 PDB header:ligase Chain: B: PDB Molecule:sidn siderophore synthetase; PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase 17 d1lcia_ 100.0 23 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 18 c3tsyA_ 100.0 22 PDB header:ligase, transferase Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein 19 c2v7bB_ 100.0 24 PDB header:ligase Chain: B: PDB Molecule:benzoate-coenzyme a ligase; PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400 20 c3l8cA_ 100.0 18 PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: structure of probable d-alanine--poly(phosphoribitol) ligase2 subunit-1 from streptococcus pyogenes 21 d1v25a_ not modelled 100.0 24 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 22 c3iplB_ not modelled 100.0 25 PDB header:ligase Chain: B: PDB Molecule:2-succinylbenzoate--coa ligase; PDBTitle: crystal structure of o-succinylbenzoic acid-coa ligase from2 staphylococcus aureus subsp. aureus mu50 23 c3nyrA_ not modelled 100.0 28 PDB header:ligase Chain: A: PDB Molecule:malonyl-coa ligase; PDBTitle: malonyl-coa ligase ternary product complex with malonyl-coa and amp2 bound 24 c3g7sA_ not modelled 100.0 21 PDB header:ligase Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1); PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus 25 c3o82B_ not modelled 100.0 26 PDB header:ligase Chain: B: PDB Molecule:peptide arylation enzyme; PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine 26 c3o82A_ not modelled 100.0 25 PDB header:ligase Chain: A: PDB Molecule:peptide arylation enzyme; PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine 27 c3ivrA_ not modelled 100.0 26 PDB header:ligase Chain: A: PDB Molecule:putative long-chain-fatty-acid coa ligase; PDBTitle: crystal structure of putative long-chain-fatty-acid coa ligase from2 rhodopseudomonas palustris cga009 28 c3e53A_ not modelled 100.0 22 PDB header:ligase Chain: A: PDB Molecule:fatty-acid-coa ligase fadd28; PDBTitle: crystal structure of n-terminal domain of a fatty acyl amp2 ligase faal28 from mycobacterium tuberculosis 29 c2y4oA_ not modelled 100.0 18 PDB header:ligase Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of paak2 in complex with phenylacetyl adenylate 30 c2y27B_ not modelled 100.0 16 PDB header:ligase Chain: B: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of paak1 in complex with atp from2 burkholderia cenocepacia 31 c3qovD_ not modelled 100.0 15 PDB header:ligase Chain: D: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of a hypothetical acyl-coa ligase (bt_0428) from2 bacteroides thetaiotaomicron vpi-5482 at 2.20 a resolution 32 c3laxA_ not modelled 99.6 15 PDB header:ligase Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: the crystal structure of a domain of phenylacetate-coenzyme2 a ligase from bacteroides vulgatus atcc 8482 33 c3hguB_ not modelled 99.5 17 PDB header:biosynthetic protein Chain: B: PDB Molecule:ehpf; PDBTitle: structure of phenazine antibiotic biosynthesis protein 34 d2ayia1 not modelled 85.0 20 Fold:Thermophilic metalloprotease-like Superfamily:Thermophilic metalloprotease-like Family:Thermophilic metalloprotease (M29) 35 c3l6cA_ not modelled 78.8 8 PDB header:isomerase Chain: A: PDB Molecule:serine racemase; PDBTitle: x-ray crystal structure of rat serine racemase in complex with2 malonate a potent inhibitor 36 d1piwa2 not modelled 66.2 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 37 c3smaD_ not modelled 58.2 20 PDB header:transferase Chain: D: PDB Molecule:frbf; PDBTitle: a new n-acetyltransferase fold in the structure and mechanism of the2 phosphonate biosynthetic enzyme frbf 38 d2nyga1 not modelled 53.8 18 Fold:TTHA0583/YokD-like Superfamily:TTHA0583/YokD-like Family:Aminoglycoside 3-N-acetyltransferase-like 39 d1pl8a2 not modelled 53.8 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 40 d1llua2 not modelled 52.8 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 41 c3ippA_ not modelled 52.1 10 PDB header:transferase Chain: A: PDB Molecule:putative thiosulfate sulfurtransferase ynje; PDBTitle: crystal structure of sulfur-free ynje 42 d1kola2 not modelled 51.5 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 43 d1f06a2 not modelled 46.8 20 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:Dihydrodipicolinate reductase-like 44 d1e3ja2 not modelled 46.7 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 45 c1uarA_ not modelled 46.3 13 PDB header:transferase Chain: A: PDB Molecule:rhodanese; PDBTitle: crystal structure of rhodanese from thermus thermophilus hb8 46 c3e4fB_ not modelled 45.6 20 PDB header:transferase Chain: B: PDB Molecule:aminoglycoside n3-acetyltransferase; PDBTitle: crystal structure of ba2930- a putative aminoglycoside n3-2 acetyltransferase from bacillus anthracis 47 d1d1ta2 not modelled 43.8 8 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 48 d1z7wa1 not modelled 42.7 10 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 49 d1v71a1 not modelled 41.0 8 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 50 c3olhA_ not modelled 39.3 8 PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: human 3-mercaptopyruvate sulfurtransferase 51 d1iz0a2 not modelled 39.0 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 52 d1jvba2 not modelled 38.4 8 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 53 c3bcxA_ not modelled 37.9 9 PDB header:transferase Chain: A: PDB Molecule:cdp-6-deoxy-l-threo-d-glycero-4-hexulose-3- PDBTitle: e1 dehydrase 54 d1vjka_ not modelled 37.4 15 Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:MoaD 55 d1e3ia2 not modelled 37.2 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 56 c2jwlB_ not modelled 35.4 14 PDB header:membrane protein Chain: B: PDB Molecule:protein tolr; PDBTitle: solution structure of periplasmic domain of tolr from h.2 influenzae with saxs data 57 d1p0fa2 not modelled 33.8 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 58 d1uufa2 not modelled 33.4 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 59 d1ykfa2 not modelled 32.5 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 60 c2ywiA_ not modelled 31.6 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical conserved protein; PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus 61 c3pc3A_ not modelled 30.4 20 PDB header:lyase Chain: A: PDB Molecule:cg1753, isoform a; PDBTitle: full length structure of cystathionine beta-synthase from drosophila2 in complex with aminoacrylate 62 c2zy3A_ not modelled 29.8 24 PDB header:lyase Chain: A: PDB Molecule:l-aspartate beta-decarboxylase; PDBTitle: dodecameric l-aspartate beta-decarboxylase 63 d1uara2 not modelled 29.5 13 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 64 d1jqba2 not modelled 29.2 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 65 d1rjwa2 not modelled 28.4 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 66 d2fzwa2 not modelled 26.2 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 67 d1udxa3 not modelled 25.6 17 Fold:Obg GTP-binding protein C-terminal domain Superfamily:Obg GTP-binding protein C-terminal domain Family:Obg GTP-binding protein C-terminal domain 68 d1zjca1 not modelled 25.5 10 Fold:Thermophilic metalloprotease-like Superfamily:Thermophilic metalloprotease-like Family:Thermophilic metalloprotease (M29) 69 d1ja1a1 not modelled 25.4 23 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:NADPH-cytochrome p450 reductase FAD-binding domain-like 70 d1liua3 not modelled 25.4 11 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:Pyruvate kinase, C-terminal domain 71 d1okga1 not modelled 25.2 10 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 72 c3aaxB_ not modelled 24.9 10 PDB header:transferase Chain: B: PDB Molecule:putative thiosulfate sulfurtransferase; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase2 cysa3 (rv3117) from mycobacterium tuberculosis: monoclinic3 form 73 d2jhfa2 not modelled 24.4 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 74 d1uaaa2 not modelled 23.4 9 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 75 d1f20a1 not modelled 22.2 11 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:NADPH-cytochrome p450 reductase FAD-binding domain-like 76 d1qora2 not modelled 22.1 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 77 d1wkva1 not modelled 21.8 10 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 78 d1cdoa2 not modelled 21.7 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 79 d1y7la1 not modelled 21.1 9 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 80 d1u3wa2 not modelled 21.1 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 81 d2g50a3 not modelled 21.0 14 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:Pyruvate kinase, C-terminal domain 82 c1okgA_ not modelled 20.5 12 PDB header:transferase Chain: A: PDB Molecule:possible 3-mercaptopyruvate sulfurtransferase; PDBTitle: 3-mercaptopyruvate sulfurtransferase from leishmania major 83 c1l9xA_ not modelled 20.4 17 PDB header:hydrolase Chain: A: PDB Molecule:gamma-glutamyl hydrolase; PDBTitle: structure of gamma-glutamyl hydrolase 84 d1l9xa_ not modelled 20.4 17 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 85 c3hjtB_ not modelled 20.2 9 PDB header:cell adhesion, transport protein Chain: B: PDB Molecule:lmb; PDBTitle: structure of laminin binding protein (lmb) of streptococcus2 agalactiae a bifunctional protein with adhesin and metal3 transporting activity 86 d2gy9p1 not modelled 19.6 17 Fold:Ribosomal protein S16 Superfamily:Ribosomal protein S16 Family:Ribosomal protein S16 87 d1aisa1 not modelled 19.4 16 Fold:TBP-like Superfamily:TATA-box binding protein-like Family:TATA-box binding protein (TBP), C-terminal domain 88 c2qjlA_ not modelled 18.9 19 PDB header:signaling protein Chain: A: PDB Molecule:ubiquitin-related modifier 1; PDBTitle: crystal structure of urm1 89 d1f8fa2 not modelled 18.8 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 90 d1m5wa_ not modelled 18.6 8 Fold:TIM beta/alpha-barrel Superfamily:Pyridoxine 5'-phosphate synthase Family:Pyridoxine 5'-phosphate synthase 91 c3iauA_ not modelled 18.4 12 PDB header:lyase Chain: A: PDB Molecule:threonine deaminase; PDBTitle: the structure of the processed form of threonine deaminase isoform 22 from solanum lycopersicum 92 d1pwha_ not modelled 18.3 10 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 93 c1aqfB_ not modelled 18.3 15 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from rabbit muscle with mg, k, and l-2 phospholactate 94 d1k92a1 not modelled 18.2 25 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 95 d1nula_ not modelled 18.1 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 96 c3a2kB_ not modelled 17.8 14 PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna 97 d1yb5a2 not modelled 17.7 8 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Alcohol dehydrogenase-like, C-terminal domain 98 d1o69a_ not modelled 17.2 14 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:GABA-aminotransferase-like 99 d1ddga1 not modelled 17.1 12 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:NADPH-cytochrome p450 reductase FAD-binding domain-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0