Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	V	I	I	V	E	D	E	F	L	A	Q	Q	E	L	S	W	L	I	K	E	H	S	Q	M	E	I	V	G	T	F	D	D	G	L	D	V	L	K	F	L	Q	H	N	R	V	D	A	I	F	L	D	I	N	I	P	S	L	D
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	V	L	L	A	Q	N	I	S	Q	F	A	H	K	P	F	I	V	F	I	T	A	W	K	E	H	A	V	E	A	F	E	L	E	A	F	D	Y	I	L	K	P	Y	Q	E	S	R	I	T	G	M	L	Q	K	L	E	A	A	W	Q
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	Q	Q	T	S	S	T	P	A	A	T	V	T	R	E	N	D	T	I	N	L	V	K	D	E	R	I	I	V	T	P	I	N	D	I	Y	Y	A	E	A	H	E	K	M	T	F	V	Y	T	R	R	E	S	Y	V	M	P	M	N	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	E	F	C	S	K	L	P	P	S	H	F	F	R	C	H	R	S	F	C	V	N	L	N	K	I	R	E	I	E	P	W	F	N	N	T	Y	I	L	R	L	K	D	L	D	F	E	V	P	V	S	R	S	K	V	K	E	F	R	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.
Sequence		L	M	H	L
Secondary structure
SS confidence
Disorder			?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2qv0 chain A Region: 1 - 122 Aligned: 122 Modelled: 122 Confidence: 100.0% Identity: 93% PDB header:transcription Chain: A: PDB Molecule:protein mrke; PDBTitle: crystal structure of the response regulatory domain of2 protein mrke from klebsiella pneumoniae Phyre2 PDB 2ayx chain A Region: 1 - 125 Aligned: 123 Modelled: 125 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:sensor kinase protein rcsc; PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain Phyre2 PDB 3eq2 chain A Region: 2 - 125 Aligned: 121 Modelled: 124 Confidence: 100.0% Identity: 22% PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: structure of hexagonal crystal form of pseudomonas2 aeruginosa rssb Phyre2 PDB 3bre chain A Region: 1 - 124 Aligned: 123 Modelled: 124 Confidence: 100.0% Identity: 15% PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: crystal structure of p.aeruginosa pa3702 Phyre2 PDB 3r0j chain A Region: 1 - 228 Aligned: 214 Modelled: 228 Confidence: 99.9% Identity: 15% PDB header:dna binding protein Chain: A: PDB Molecule:possible two component system response transcriptional PDBTitle: structure of phop from mycobacterium tuberculosis Phyre2 PDB 1w25 chain B Region: 2 - 137 Aligned: 134 Modelled: 136 Confidence: 99.9% Identity: 20% PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp Phyre2 PDB 1ny5 chain A domain 1 Region: 1 - 137 Aligned: 135 Modelled: 137 Confidence: 99.9% Identity: 19% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3i5a chain A Region: 2 - 125 Aligned: 123 Modelled: 124 Confidence: 99.9% Identity: 15% PDB header:signaling protein Chain: A: PDB Molecule:response regulator/ggdef domain protein; PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae Phyre2 PDB 3b2n chain A Region: 1 - 116 Aligned: 116 Modelled: 116 Confidence: 99.9% Identity: 24% PDB header:transcription Chain: A: PDB Molecule:uncharacterized protein q99uf4; PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus Phyre2 PDB 1ny5 chain A Region: 1 - 124 Aligned: 122 Modelled: 124 Confidence: 99.9% Identity: 21% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigm54 activator (aaa+ atpase) in the inactive2 state Phyre2 PDB 1jbe chain A Region: 1 - 120 Aligned: 119 Modelled: 120 Confidence: 99.9% Identity: 26% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3cu5 chain B Region: 1 - 125 Aligned: 125 Modelled: 125 Confidence: 99.9% Identity: 24% PDB header:transcription regulator Chain: B: PDB Molecule:two component transcriptional regulator, arac family; PDBTitle: crystal structure of a two component transcriptional regulator arac2 from clostridium phytofermentans isdg Phyre2 PDB 2ayx chain A domain 1 Region: 1 - 125 Aligned: 123 Modelled: 125 Confidence: 99.9% Identity: 24% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1ys7 chain B Region: 2 - 230 Aligned: 221 Modelled: 229 Confidence: 99.9% Identity: 19% PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulatory protein prra; PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+ Phyre2 PDB 1a2o chain B Region: 1 - 117 Aligned: 116 Modelled: 117 Confidence: 99.9% Identity: 27% PDB header:bacterial chemotaxis Chain: B: PDB Molecule:cheb methylesterase; PDBTitle: structural basis for methylesterase cheb regulation by a2 phosphorylation-activated domain Phyre2 PDB 1kgs chain A domain 2 Region: 1 - 121 Aligned: 119 Modelled: 121 Confidence: 99.9% Identity: 22% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3eul chain B Region: 1 - 117 Aligned: 117 Modelled: 117 Confidence: 99.9% Identity: 20% PDB header:transcription Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis Phyre2 PDB 1dz3 chain A Region: 1 - 118 Aligned: 118 Modelled: 118 Confidence: 99.9% Identity: 30% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1s8n chain A Region: 1 - 131 Aligned: 129 Modelled: 131 Confidence: 99.9% Identity: 26% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3dzd chain A Region: 2 - 130 Aligned: 127 Modelled: 129 Confidence: 99.9% Identity: 20% PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state Phyre2 PDB 2hqr chain A Region: 1 - 232 Aligned: 215 Modelled: 215 Confidence: 99.9% Identity: 13% PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism Phyre2 1 c2qv0A_ 2 c2ayxA_ 3 c3eq2A_ 4 c3breA_ 5 c3r0jA_ 6 c1w25B_ 7 d1ny5a1 8 c3i5aA_ 9 c3b2nA_ 10 c1ny5A_ 11 d1jbea_ 12 c3cu5B_ 13 d2ayxa1 14 c1ys7B_ 15 c1a2oB_ 16 d1kgsa2 17 c3eulB_ 18 d1dz3a_ 19 d1s8na_ 20 c3dzdA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 c2hqrA_ 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2qv0A_ 100.0 93 PDB header:transcription Chain: A: PDB Molecule:protein mrke; PDBTitle: crystal structure of the response regulatory domain of2 protein mrke from klebsiella pneumoniae 2 c2ayxA_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:sensor kinase protein rcsc; PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain 3 c3eq2A_ 100.0 22 PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: structure of hexagonal crystal form of pseudomonas2 aeruginosa rssb 4 c3breA_ 100.0 15 PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: crystal structure of p.aeruginosa pa3702 5 c3r0jA_ 99.9 15 PDB header:dna binding protein Chain: A: PDB Molecule:possible two component system response transcriptional PDBTitle: structure of phop from mycobacterium tuberculosis 6 c1w25B_ 99.9 20 PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp 7 d1ny5a1 99.9 19 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 8 c3i5aA_ 99.9 15 PDB header:signaling protein Chain: A: PDB Molecule:response regulator/ggdef domain protein; PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae 9 c3b2nA_ 99.9 24 PDB header:transcription Chain: A: PDB Molecule:uncharacterized protein q99uf4; PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus 10 c1ny5A_ 99.9 21 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigm54 activator (aaa+ atpase) in the inactive2 state 11 d1jbea_ 99.9 26 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 12 c3cu5B_ 99.9 24 PDB header:transcription regulator Chain: B: PDB Molecule:two component transcriptional regulator, arac family; PDBTitle: crystal structure of a two component transcriptional regulator arac2 from clostridium phytofermentans isdg 13 d2ayxa1 99.9 24 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 14 c1ys7B_ 99.9 19 PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulatory protein prra; PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+ 15 c1a2oB_ 99.9 27 PDB header:bacterial chemotaxis Chain: B: PDB Molecule:cheb methylesterase; PDBTitle: structural basis for methylesterase cheb regulation by a2 phosphorylation-activated domain 16 d1kgsa2 99.9 22 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 17 c3eulB_ 99.9 20 PDB header:transcription Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis 18 d1dz3a_ 99.9 30 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 19 d1s8na_ 99.9 26 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 20 c3dzdA_ 99.9 20 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state 21 c3cfyA_ not modelled 99.9 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative luxo repressor protein; PDBTitle: crystal structure of signal receiver domain of putative luxo2 repressor protein from vibrio parahaemolyticus 22 d1qkka_ not modelled 99.9 19 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 23 d1a04a2 not modelled 99.9 21 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 24 d1ys7a2 not modelled 99.9 28 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 25 d1w25a1 not modelled 99.9 20 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 26 d1u0sy_ not modelled 99.9 26 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 27 c2rjnA_ not modelled 99.9 20 PDB header:hydrolase Chain: A: PDB Molecule:response regulator receiver:metal-dependent PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis 28 d2a9pa1 not modelled 99.9 25 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 29 d1mvoa_ not modelled 99.9 29 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 30 d2pl1a1 not modelled 99.9 24 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 31 d1k66a_ not modelled 99.9 24 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 32 d1yioa2 not modelled 99.9 22 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 33 d1dbwa_ not modelled 99.9 24 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 34 d1heya_ not modelled 99.9 25 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 35 c3cz5B_ not modelled 99.9 19 PDB header:transcription regulator Chain: B: PDB Molecule:two-component response regulator, luxr family; PDBTitle: crystal structure of two-component response regulator, luxr family,2 from aurantimonas sp. si85-9a1 36 c3cnbC_ not modelled 99.9 16 PDB header:dna binding protein Chain: C: PDB Molecule:dna-binding response regulator, merr family; PDBTitle: crystal structure of signal receiver domain of dna binding response2 regulator protein (merr) from colwellia psychrerythraea 34h 37 c3h1gA_ not modelled 99.9 22 PDB header:signaling protein Chain: A: PDB Molecule:chemotaxis protein chey homolog; PDBTitle: crystal structure of chey mutant t84a of helicobacter pylori 38 c3khtA_ not modelled 99.9 20 PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator from hahella chejuensis 39 c3hdgE_ not modelled 99.9 27 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the n-terminal domain of an2 uncharacterized protein (ws1339) from wolinella3 succinogenes 40 c2zwmA_ not modelled 99.9 24 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein yycf; PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis 41 c3hebB_ not modelled 99.9 20 PDB header:transcription regulator Chain: B: PDB Molecule:response regulator receiver domain protein (chey); PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum 42 c3jteA_ not modelled 99.9 19 PDB header:protein binding Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator receiver domain2 protein from clostridium thermocellum 43 c3gt7A_ not modelled 99.9 21 PDB header:hydrolase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of signal receiver domain of signal2 transduction histidine kinase from syntrophus3 aciditrophicus 44 d1peya_ not modelled 99.9 23 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 45 c3hv2B_ not modelled 99.9 18 PDB header:signaling protein Chain: B: PDB Molecule:response regulator/hd domain protein; PDBTitle: crystal structure of signal receiver domain of hd domain-2 containing protein from pseudomonas fluorescens pf-5 46 d1zh2a1 not modelled 99.9 23 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 47 d1krwa_ not modelled 99.9 26 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 48 c3t8yA_ not modelled 99.9 24 PDB header:hydrolase Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate PDBTitle: crystal structure of the response regulator domain of thermotoga2 maritima cheb 49 d1p6qa_ not modelled 99.9 23 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 50 d2r25b1 not modelled 99.9 24 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 51 c2jrlA_ not modelled 99.9 22 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer 52 c3nhzA_ not modelled 99.9 21 PDB header:dna binding protein Chain: A: PDB Molecule:two component system transcriptional regulator mtra; PDBTitle: structure of n-terminal domain of mtra 53 c2qr3A_ not modelled 99.9 22 PDB header:transcription Chain: A: PDB Molecule:two-component system response regulator; PDBTitle: crystal structure of the n-terminal signal receiver domain of two-2 component system response regulator from bacteroides fragilis 54 d1a2oa1 not modelled 99.9 24 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 55 c1kgsA_ not modelled 99.9 18 PDB header:dna binding protein Chain: A: PDB Molecule:dna binding response regulator d; PDBTitle: crystal structure at 1.50 a of an ompr/phob homolog from thermotoga2 maritima 56 d1zesa1 not modelled 99.9 21 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 57 c2qzjC_ not modelled 99.9 20 PDB header:transcription Chain: C: PDB Molecule:two-component response regulator; PDBTitle: crystal structure of a two-component response regulator from2 clostridium difficile 58 c3rqiA_ not modelled 99.9 17 PDB header:transcription Chain: A: PDB Molecule:response regulator protein; PDBTitle: crystal structure of a response regulator protein from burkholderia2 pseudomallei with a phosphorylated aspartic acid, calcium ion and3 citrate 59 c3crnA_ not modelled 99.9 15 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver domain protein, chey-like; PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1 60 c2zayA_ not modelled 99.9 10 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans 61 d1zgza1 not modelled 99.9 25 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 62 c2qvgA_ not modelled 99.9 18 PDB header:transferase Chain: A: PDB Molecule:two component response regulator; PDBTitle: the crystal structure of a two-component response regulator2 from legionella pneumophila 63 c2gwrA_ not modelled 99.9 18 PDB header:signaling protein Chain: A: PDB Molecule:dna-binding response regulator mtra; PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis 64 c3t6kB_ not modelled 99.9 23 PDB header:signaling protein Chain: B: PDB Molecule:response regulator receiver; PDBTitle: crystal structure of a hypothetical response regulator (caur_3799)2 from chloroflexus aurantiacus j-10-fl at 1.86 a resolution 65 d1i3ca_ not modelled 99.9 25 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 66 c1p2fA_ not modelled 99.9 21 PDB header:transcription Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure analysis of response regulator drrb, a2 thermotoga maritima ompr/phob homolog 67 d1p2fa2 not modelled 99.9 21 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 68 c3kcnA_ not modelled 99.9 17 PDB header:lyase Chain: A: PDB Molecule:adenylate cyclase homolog; PDBTitle: the crystal structure of adenylate cyclase from2 rhodopirellula baltica 69 c2jk1A_ not modelled 99.9 14 PDB header:dna-binding Chain: A: PDB Molecule:hydrogenase transcriptional regulatory protein hupr1; PDBTitle: crystal structure of the wild-type hupr receiver domain 70 c2hqrA_ 99.9 13 PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism 71 c3f6cB_ not modelled 99.9 16 PDB header:dna binding protein Chain: B: PDB Molecule:positive transcription regulator evga; PDBTitle: crystal structure of n-terminal domain of positive transcription2 regulator evga from escherichia coli 72 c3ilhA_ not modelled 99.9 17 PDB header:transcription regulator Chain: A: PDB Molecule:two component response regulator; PDBTitle: crystal structure of two component response regulator from cytophaga2 hutchinsonii 73 c3cg0A_ not modelled 99.9 26 PDB header:lyase Chain: A: PDB Molecule:response regulator receiver modulated diguanylate cyclase PDBTitle: crystal structure of signal receiver domain of modulated diguanylate2 cyclase from desulfovibrio desulfuricans g20, an example of alternate3 folding 74 d1xhfa1 not modelled 99.9 25 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 75 d1mb3a_ not modelled 99.9 24 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 76 c2oqrA_ not modelled 99.9 16 PDB header:transcription,signaling protein Chain: A: PDB Molecule:sensory transduction protein regx3; PDBTitle: the structure of the response regulator regx3 from mycobacterium2 tuberculosis 77 c3hzhA_ not modelled 99.9 20 PDB header:signaling protein Chain: A: PDB Molecule:chemotaxis response regulator (chey-3); PDBTitle: crystal structure of the chex-chey-bef3-mg+2 complex from2 borrelia burgdorferi 78 c3mmnA_ not modelled 99.9 20 PDB header:transferase Chain: A: PDB Molecule:histidine kinase homolog; PDBTitle: crystal structure of the receiver domain of the histidine kinase cki12 from arabidopsis thaliana complexed with mg2+ 79 c3lteH_ not modelled 99.9 19 PDB header:transcription Chain: H: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator (signal receiver domain) from2 bermanella marisrubri 80 c3m6mF_ not modelled 99.9 19 PDB header:lyase/transferase Chain: F: PDB Molecule:sensory/regulatory protein rpfc; PDBTitle: crystal structure of rpff complexed with rec domain of rpfc 81 c3q9sA_ not modelled 99.9 22 PDB header:dna binding protein Chain: A: PDB Molecule:dna-binding response regulator; PDBTitle: crystal structure of rra(1-215) from deinococcus radiodurans 82 c3cg4A_ not modelled 99.9 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:response regulator receiver domain protein (chey-like); PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1 83 c3n0rA_ not modelled 99.9 19 PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: structure of the phyr stress response regulator at 1.25 angstrom2 resolution 84 c3a0rB_ not modelled 99.9 22 PDB header:transferase Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360) 85 c2rdmB_ not modelled 99.9 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator receiver protein from2 sinorhizobium medicae wsm419 86 d1k68a_ not modelled 99.9 20 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 87 c2qxyB_ not modelled 99.9 18 PDB header:transcription Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of a response regulator from thermotoga2 maritima 88 c3grcD_ not modelled 99.9 18 PDB header:transferase Chain: D: PDB Molecule:sensor protein, kinase; PDBTitle: crystal structure of a sensor protein from polaromonas sp.2 js666 89 c3i42A_ not modelled 99.9 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:response regulator receiver domain protein (chey- PDBTitle: structure of response regulator receiver domain (chey-like)2 from methylobacillus flagellatus 90 c3hdvB_ not modelled 99.9 19 PDB header:transcription regulator Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator receiver protein from2 pseudomonas putida 91 c3c3mA_ not modelled 99.9 20 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of the n-terminal domain of response regulator2 receiver protein from methanoculleus marisnigri jr1 92 c3gl9B_ not modelled 99.9 23 PDB header:signaling protein Chain: B: PDB Molecule:response regulator; PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism 93 d2b4aa1 not modelled 99.9 15 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 94 c3eqzB_ not modelled 99.9 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of a response regulator from colwellia2 psychrerythraea 95 c3nhmA_ not modelled 99.9 22 PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure of a response regulator from myxococcus xanthus 96 d1w25a2 not modelled 99.9 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 97 c1zn2A_ not modelled 99.9 23 PDB header:transcription regulator Chain: A: PDB Molecule:response regulatory protein; PDBTitle: low resolution structure of response regulator styr 98 c3snkA_ not modelled 99.9 11 PDB header:signaling protein Chain: A: PDB Molecule:response regulator chey-like protein; PDBTitle: crystal structure of a response regulator chey-like protein (mll6475)2 from mesorhizobium loti at 2.02 a resolution 99 c3c97A_ not modelled 99.9 21 PDB header:signaling protein, transferase Chain: A: PDB Molecule:signal transduction histidine kinase; PDBTitle: crystal structure of the response regulator receiver domain2 of a signal transduction histidine kinase from aspergillus3 oryzae 100 c2hqoA_ not modelled 99.9 18 PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism 101 c3h5iA_ not modelled 99.9 23 PDB header:transcription Chain: A: PDB Molecule:response regulator/sensory box protein/ggdef PDBTitle: crystal structure of the n-terminal domain of a response2 regulator/sensory box/ggdef 3-domain protein from3 carboxydothermus hydrogenoformans 102 c3luaA_ not modelled 99.9 15 PDB header:transcription regulator Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of a signal receiver domain of two component signal2 transduction (histidine kinase) from clostridium thermocellum 103 c3eodA_ not modelled 99.8 26 PDB header:signaling protein Chain: A: PDB Molecule:protein hnr; PDBTitle: crystal structure of n-terminal domain of e. coli rssb 104 c2j48A_ not modelled 99.8 20 PDB header:transferase Chain: A: PDB Molecule:two-component sensor kinase; PDBTitle: nmr structure of the pseudo-receiver domain of the cika2 protein. 105 d1dcfa_ not modelled 99.8 19 Fold:Flavodoxin-like Superfamily:CheY-like Family:Receiver domain of the ethylene receptor 106 c3ktoA_ not modelled 99.8 15 PDB header:transcription regulator Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator receiver protein2 from pseudoalteromonas atlantica 107 c2nt3A_ not modelled 99.8 19 PDB header:signaling protein Chain: A: PDB Molecule:response regulator homolog; PDBTitle: receiver domain from myxococcus xanthus social motility protein frzs2 (y102a mutant) 108 c2qsjB_ not modelled 99.8 24 PDB header:transcription Chain: B: PDB Molecule:dna-binding response regulator, luxr family; PDBTitle: crystal structure of a luxr family dna-binding response2 regulator from silicibacter pomeroyi 109 c3lufB_ not modelled 99.8 15 PDB header:signaling protein Chain: B: PDB Molecule:two-component system response regulator/ggdef PDBTitle: structure of probable two-component system response2 regulator/ggdef domain protein 110 c3kyiB_ not modelled 99.8 25 PDB header:transferase Chain: B: PDB Molecule:chey6 protein; PDBTitle: crystal structure of the phosphorylated p1 domain of chea3 in complex2 with chey6 from r. sphaeroides 111 d1qo0d_ not modelled 99.8 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:Positive regulator of the amidase operon AmiR 112 c3c3wB_ not modelled 99.8 19 PDB header:transcription Chain: B: PDB Molecule:two component transcriptional regulatory protein devr; PDBTitle: crystal structure of the mycobacterium tuberculosis hypoxic response2 regulator dosr 113 c1rnlA_ not modelled 99.7 21 PDB header:signal transduction protein Chain: A: PDB Molecule:nitrate/nitrite response regulator protein narl; PDBTitle: the nitrate/nitrite response regulator protein narl from narl 114 c3n53B_ not modelled 99.7 21 PDB header:transcription Chain: B: PDB Molecule:response regulator receiver modulated diguanylate cyclase; PDBTitle: crystal structure of a response regulator receiver modulated2 diguanylate cyclase from pelobacter carbinolicus 115 c2yxbA_ not modelled 99.7 14 PDB header:isomerase Chain: A: PDB Molecule:coenzyme b12-dependent mutase; PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix 116 c3d6wA_ not modelled 99.7 33 PDB header:dna binding protein Chain: A: PDB Molecule:methyl-accepting/dna response regulator; PDBTitle: lyttr dna-binding domain of putative methyl-accepting/dna response2 regulator from bacillus cereus. 117 c3cwoX_ not modelled 99.7 19 PDB header:de novo protein Chain: X: PDB Molecule:beta/alpha-barrel protein based on 1thf and 1tmy; PDBTitle: a beta/alpha-barrel built by the combination of fragments2 from different folds 118 c3bs1A_ not modelled 99.3 24 PDB header:transcription regulator Chain: A: PDB Molecule:accessory gene regulator protein a; PDBTitle: structure of the staphylococcus aureus agra lyttr domain2 bound to dna reveals a beta fold with a novel mode of3 binding 119 d1fmfa_ not modelled 99.3 10 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 120 c3klnC_ not modelled 99.0 9 PDB header:transcription Chain: C: PDB Molecule:transcriptional regulator, luxr family; PDBTitle: vibrio cholerae vpst

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0