Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AEK2
DateThu Jan 5 11:23:33 GMT 2012
Unique Job IDc9b5bfffd9db0d50

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1q7ba_
Top template information
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
Confidence and coverage
Confidence:100.0% Coverage:100%
243 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNV
Secondary structure 
SS confidence 
Disorder  ?????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  TDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  VMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITVNVVA
Secondary structure 
SS confidence 
Disorder 
?
????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  PGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETLHVNGG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   ....
Sequence  MYMV
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1q7b chain A

3D model

Region: 2 - 244
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 100%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1hdc chain A

3D model

Region: 2 - 243
Aligned: 242
Modelled: 242
Confidence: 100.0%
Identity: 37%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3emk chain A

3D model

Region: 1 - 244
Aligned: 239
Modelled: 244
Confidence: 100.0%
Identity: 52%
PDB header:oxidoreductase
Chain: A: PDB Molecule:glucose/ribitol dehydrogenase;
PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis

Phyre2

PDB 1k2w chain A

3D model

Region: 1 - 243
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 33%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3lf2 chain B

3D model

Region: 1 - 243
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 30%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center

Phyre2

PDB 3rih chain B

3D model

Region: 1 - 243
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus

Phyre2

PDB 3ak4 chain C

3D model

Region: 1 - 243
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens

Phyre2

PDB 2pd6 chain D

3D model

Region: 2 - 241
Aligned: 240
Modelled: 240
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase
Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8;
PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8

Phyre2

PDB 3cxt chain A

3D model

Region: 1 - 243
Aligned: 239
Modelled: 243
Confidence: 100.0%
Identity: 38%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2

Phyre2

PDB 1fmc chain A

3D model

Region: 1 - 242
Aligned: 242
Modelled: 242
Confidence: 100.0%
Identity: 29%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2p68 chain A

3D model

Region: 1 - 242
Aligned: 242
Modelled: 242
Confidence: 100.0%
Identity: 50%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5

Phyre2

PDB 2ae2 chain A

3D model

Region: 1 - 243
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 31%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1ae1 chain A

3D model

Region: 1 - 243
Aligned: 236
Modelled: 243
Confidence: 100.0%
Identity: 31%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3svt chain A

3D model

Region: 2 - 243
Aligned: 242
Modelled: 242
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans

Phyre2

PDB 1w6u chain A

3D model

Region: 1 - 244
Aligned: 241
Modelled: 244
Confidence: 100.0%
Identity: 26%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1xhl chain A

3D model

Region: 2 - 244
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3pk0 chain B

3D model

Region: 1 - 243
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of short-chain dehydrogenase/reductase sdr from2 mycobacterium smegmatis

Phyre2

PDB 2c07 chain A

3D model

Region: 1 - 242
Aligned: 237
Modelled: 242
Confidence: 100.0%
Identity: 47%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: oxoacyl-acp reductase of plasmodium falciparum

Phyre2

PDB 2c07 chain A domain 1

3D model

Region: 1 - 242
Aligned: 237
Modelled: 242
Confidence: 100.0%
Identity: 47%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3gvc chain B

3D model

Region: 2 - 244
Aligned: 243
Modelled: 243
Confidence: 100.0%
Identity: 32%
PDB header:oxidoreductase
Chain: B: PDB Molecule:probable short-chain type
PDBTitle: crystal structure of probable short-chain dehydrogenase-2 reductase from mycobacterium tuberculosis

Phyre2
1
d1q7ba_
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d1hdca_
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c3emkA_
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d1k2wa_
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c3lf2B_
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c3rihB_
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c3ak4C_
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c2pd6D_
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c3cxtA_
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d1fmca_
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c2p68A_
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d2ae2a_
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d1ae1a_
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c3svtA_
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d1w6ua_
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d1xhla_
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c3pk0B_
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c2c07A_
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d2c07a1
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c3gvcB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1q7ba_
100.0 100 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
2d1hdca_
100.0 37 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
3c3emkA_
100.0 52 PDB header:oxidoreductase
Chain: A: PDB Molecule:glucose/ribitol dehydrogenase;
PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis
4d1k2wa_
100.0 33 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
5c3lf2B_
100.0 30 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain oxidoreductase q9hya2;
PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center
6c3rihB_
100.0 33 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus
7c3ak4C_
100.0 34 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase;
PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens
8c2pd6D_
100.0 33 PDB header:oxidoreductase
Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8;
PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8
9c3cxtA_
100.0 38 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase with different specificities;
PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2
10d1fmca_
100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
11c2p68A_
100.0 50 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
12d2ae2a_
100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13d1ae1a_
100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
14c3svtA_
100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans
15d1w6ua_
100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
16d1xhla_
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
17c3pk0B_
100.0 33 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of short-chain dehydrogenase/reductase sdr from2 mycobacterium smegmatis
18c2c07A_
100.0 47 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: oxoacyl-acp reductase of plasmodium falciparum
19d2c07a1
100.0 47 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
20c3gvcB_
100.0 32 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable short-chain type
PDBTitle: crystal structure of probable short-chain dehydrogenase-2 reductase from mycobacterium tuberculosis
21c2uvdE_
not modelled 100.0 56 PDB header:oxidoreductase
Chain: E: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: the crystal structure of a 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis (ba3989)
22d1iy8a_
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
23c3toxG_
not modelled 100.0 36 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
24c2zatC_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4;
PDBTitle: crystal structure of a mammalian reductase
25d1nffa_
not modelled 100.0 35 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
26d1pr9a_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
27c3nugA_
not modelled 100.0 38 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase;
PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti
28c3uf0A_
not modelled 100.0 35 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a putative nad(p) dependent gluconate 5-2 dehydrogenase from beutenbergia cavernae(efi target efi-502044) with3 bound nadp (low occupancy)
29c3gk3D_
not modelled 100.0 44 PDB header:oxidoreductase
Chain: D: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetoacetyl-coa reductase from2 burkholderia pseudomallei 1710b
30d1yxma1
not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
31d1geea_
not modelled 100.0 33 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
32d1ydea1
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
33c3gr6A_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of the staphylococcus aureus enoyl-acyl2 carrier protein reductase (fabi) in complex with nadp and3 triclosan
34c2cfcB_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
35d1h5qa_
not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
36c3k31B_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
37d1ulsa_
not modelled 100.0 39 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
38d1zema1
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
39d1bdba_
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
40c3ftpD_
not modelled 100.0 60 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein)2 reductase from burkholderia pseudomallei at 2.05 a3 resolution
41d1xkqa_
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
42c3ai3A_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph-sorbose reductase;
PDBTitle: the crystal structure of l-sorbose reductase from gluconobacter2 frateurii complexed with nadph and l-sorbose
43c2z1nA_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of ape0912 from aeropyrum pernix k1
44d2bgka1
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
45c2q2qG_
not modelled 100.0 34 PDB header:oxidoreductase
Chain: G: PDB Molecule:beta-d-hydroxybutyrate dehydrogenase;
PDBTitle: structure of d-3-hydroxybutyrate dehydrogenase from pseudomonas putida
46d2a4ka1
not modelled 100.0 32 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
47c3imfA_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:short chain dehydrogenase;
PDBTitle: 1.99 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor'
48d1g0oa_
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
49c1w4zA_
not modelled 100.0 40 PDB header:antibiotic biosynthesis
Chain: A: PDB Molecule:ketoacyl reductase;
PDBTitle: structure of actinorhodin polyketide (actiii) reductase
50c2wdzD_
not modelled 100.0 35 PDB header:oxidoreductase
Chain: D: PDB Molecule:short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of the short chain dehydrogenase2 galactitol-dehydrogenase (gatdh) of rhodobacter3 sphaeroides in complex with nad+ and 1,2-pentandiol
51d1hxha_
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
52c3f9iB_
not modelled 100.0 41 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase2 rickettsia prowazekii
53d2rhca1
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
54c2b4qB_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl-
PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex
55c2p91A_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh];
PDBTitle: crystal structure of enoyl-[acyl-carrier-protein] reductase (nadh)2 from aquifex aeolicus vf5
56c3v2gA_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of a dehydrogenase/reductase from sinorhizobium2 meliloti 1021
57c3oidA_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph];
PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl)
58c3iccA_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution
59c3ijrF_
not modelled 100.0 24 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
60d2pd4a1
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
61c3grkE_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
62c3itdA_
not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:17beta-hydroxysteroid dehydrogenase;
PDBTitle: crystal structure of an inactive 17beta-hydroxysteroid dehydrogenase2 (y167f mutated form) from fungus cochliobolus lunatus
63d2d1ya1
not modelled 100.0 36 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
64d2ew8a1
not modelled 100.0 37 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
65c3ezlA_
not modelled 100.0 44 PDB header:oxidoreductase
Chain: A: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetyacetyl-coa reductase from2 burkholderia pseudomallei 1710b
66c3lylB_
not modelled 100.0 59 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
67c3osuA_
not modelled 100.0 54 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of the 3-oxoacyl-acyl carrier protein reductase,2 fabg, from staphylococcus aureus
68d1o5ia_
not modelled 100.0 35 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
69c3sjuA_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:keto reductase;
PDBTitle: hedamycin polyketide ketoreductase bound to nadph
70c3gdfA_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase;
PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
71d1edoa_
not modelled 100.0 50 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
72c3rkuC_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase ymr226c;
PDBTitle: substrate fingerprint and the structure of nadp+ dependent serine2 dehydrogenase from saccharomyces cerevisiae complexed with nadp+
73d1ja9a_
not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
74d1cyda_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
75d1zk4a1
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
76c3o38D_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: D: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis
77c3uxyC_
not modelled 100.0 34 PDB header:oxidoreductase
Chain: C: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: the crystal structure of short chain dehydrogenase from rhodobacter2 sphaeroides
78c3ppiA_
not modelled 100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium
79c3r3sD_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase;
PDBTitle: structure of the ygha oxidoreductase from salmonella enterica
80c3afnC_
not modelled 100.0 31 PDB header:oxidoreductase
Chain: C: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of aldose reductase a1-r complexed with nadp
81c3ek2D_
not modelled 100.0 23 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b
82d1qsga_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
83d1ulua_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
84d1vl8a_
not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
85c3n74A_
not modelled 100.0 32 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 brucella melitensis
86d1gega_
not modelled 100.0 32 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
87d1e6wa_
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
88c3t7cC_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium avium2 bound to nad
89c3bmrA_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:pteridine reductase;
PDBTitle: structure of pteridine reductase 1 (ptr1) from trypanosoma2 brucei in ternary complex with cofactor (nadp+) and3 inhibitor (compound ax6)
90c2qioA_
not modelled 100.0 25 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
91d1x1ta1
not modelled 100.0 35 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
92d1spxa_
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
93c2jjyD_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of francisella tularensis enoyl reductase2 (ftfabi) with bound nad
94c3ctmH_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: H: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity
95c3r1iB_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain type dehydrogenase/reductase;
PDBTitle: crystal structure of a short-chain type dehydrogenase/reductase from2 mycobacterium marinum
96c3pgxB_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: B: PDB Molecule:carveol dehydrogenase;
PDBTitle: crystal structure of a putative carveol dehydrogenase from2 mycobacterium paratuberculosis bound to nicotinamide adenine3 dinucleotide
97c2ph3B_
not modelled 100.0 47 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-[acyl carrier protein] reductase;
PDBTitle: crystal structure of 3-oxoacyl-[acyl carrier protein] reductase2 ttha0415 from thermus thermophilus
98c3uveC_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: C: PDB Molecule:carveol dehydrogenase ((+)-trans-carveol dehydrogenase);
PDBTitle: crystal structure of carveol dehydrogenase ((+)-trans-carveol2 dehydrogenase) from mycobacterium avium
99c2dteB_
not modelled 100.0 36 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh
100c3i4fD_
not modelled 100.0 33 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
101c3oecA_
not modelled 100.0 37 PDB header:oxidoreductase
Chain: A: PDB Molecule:carveol dehydrogenase (mytha.01326.c, a0r518 homolog);
PDBTitle: crystal structure of carveol dehydrogenase from mycobacterium2 thermoresistibile
102c3v8bC_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dehydrogenase, possibly 3-oxoacyl-[acyl-carrier
PDBTitle: crystal structure of a 3-ketoacyl-acp reductase from sinorhizobium2 meliloti 1021
103c3llsB_
not modelled 100.0 40 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase from2 mycobacterium tuberculosis
104d2ag5a1
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
105c2et6A_
not modelled 100.0 35 PDB header:oxidoreductase
Chain: A: PDB Molecule:(3r)-hydroxyacyl-coa dehydrogenase;
PDBTitle: (3r)-hydroxyacyl-coa dehydrogenase domain of candida tropicalis2 peroxisomal multifunctional enzyme type 2
106c3v2hB_
not modelled 100.0 35 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-beta-hydroxybutyrate dehydrogenase;
PDBTitle: the crystal structure of d-beta-hydroxybutyrate dehydrogenase from2 sinorhizobium meliloti
107d1p33a_
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
108c2qhxB_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: B: PDB Molecule:pteridine reductase 1;
PDBTitle: structure of pteridine reductase from leishmania major2 complexed with a ligand
109c3diiB_
not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of a carbohydrate specific scor enzyme2 from clostridium thermocellum, ligand-free form
110c2fwmX_
not modelled 100.0 36 PDB header:oxidoreductase
Chain: X: PDB Molecule:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase;
PDBTitle: crystal structure of e. coli enta, a 2,3-dihydrodihydroxy benzoate2 dehydrogenase
111d2gdza1
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
112c3un1D_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: D: PDB Molecule:probable oxidoreductase;
PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021
113d1uzma1
not modelled 100.0 42 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
114d1mxha_
not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
115c2nm0B_
not modelled 100.0 43 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2)
116c3e03C_
not modelled 100.0 25 PDB header:oxidoreductase
Chain: C: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a putative dehydrogenase from2 xanthomonas campestris
117c2hq1A_
not modelled 100.0 34 PDB header:oxidoreductase
Chain: A: PDB Molecule:glucose/ribitol dehydrogenase;
PDBTitle: crystal structure of orf 1438 a putative glucose/ribitol2 dehydrogenase from clostridium thermocellum
118c3s55F_
not modelled 100.0 36 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative short-chain dehydrogenase/reductase;
PDBTitle: crystal structure of a putative short-chain dehydrogenase/reductase2 from mycobacterium abscessus bound to nad
119c3t4xA_
not modelled 100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: short chain dehydrogenase/reductase family oxidoreductase from2 bacillus anthracis str. ames ancestor
120d1uaya_
not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0