Reference sequence (query): batch____ Identities normalised by aligned length. Colored by: property
HSP processing: ranked Search cycle: 2
1 [ . . . . : . . . . 1 . . . . : . . . . 2 . . . . : . . . . 3 . . . . : . . . . 4 . . . . : . . . ] 486
batch____ bits E-value N 100.0% 1:486 MGNNLLSAKATLPVYDLNNLAPRIVHLGFGAFHRAHQGVYADILATEHFSDWGYYEVNLIGGEQQIADLQQQDNLYTVAEMSADVWTARVVGVVKKALHVQIDGLETVLAAMCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVAADVQNPHQPKTATGVIVEALARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAVDVKLAQWIEDNVTFPSTMVDRIVPAVTEDTLAKIEQLTGVRDPAGVACEPFRQWVIEDNFVAGRPEWEKAGAELVSDVLPYEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHYRYAAYGLMLQEQAPTLKVQGVDLQDYANRLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKFDLLALGVAGWMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGKARVQSLLAIKAIFGDDLPDNSLFTARVTETYLSLLAHGAKATVAKYSVK
1 UniRef50_P33029 Uncharacterized oxidoreduct... 588 1e-166 1 52.9% 1:480 4:482 IASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLVEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDEQAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHQGRETDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQ-RVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQAL------
2 UniRef50_C6D940 Mannitol dehydrogenase doma... 583 1e-165 1 53.9% 6:484 13:491 -----LPASVQFPRYDRKALKPRIVHIGFGAFHRAHQALLTDRVLNMVGGDWGICEVVLFSDDTMINALRQQDHLFTVLEKAATSNQPIVVGAVCESLHAKIEGINAIIEKLAAPETAIVSLTITEKGYCMDGTSGKLDRTNKLIQQDLIDPRRPVSVPGLLAEALRLRHERGIAPFTVLSCDNVPENGKTAKAAVLESAGINDRNLIDWIEAQVSFPNTMVDRIVPAATPETLQEIADHLGVADPCAIACEPFIQWVIEDHFTAGRPEWEKAGVQLVHDVLPFEEMKLRMLNGSHSFLAYLGYLAGYDHVSDCMNDENYRRAVSHLMLLEQAPTLSVVDIDLKDYAVQLLTRFSNPALKHRTWQIAMDGSQKLPQRMLESLRWHVSNGGDYRCLALGIAGWMRYVSGKDDAGNPIEIRDPLADKLRHVVEETSDSAERVSAFLNIRSIFGEDLPANHDVFNAIAQAYLKLRDHGAKNTVAALA--
3 UniRef50_Q21M76 Mannitol dehydrogenase-like... 581 1e-164 1 43.8% 1:482 4:488 INNDLLAsaIQLPQYDRAGVKPGIVHLGIGAFHRAHQAFYTEAVLNQFGGDWGIIGCSLRSASVKT-QLAEQDGLYTLVERGPEGEKFQIMGAVQQVV-VGPEDPAALVAIMANPQTQIVSLTVTEKGYCHDPATGNLNLSHPDIQHDLGNLNAPKSAIGYIVAALLARKESGQSSFTVLSCDNLPNNGEVLEKVVLQFAKQVSAELCEWVSAHTKFPSTMIDRIVPATTDSDRADLEAKVGYRDEGMVVAEPFTQWVIEDKFCSARPQWEQVGALLVEDVTAFEKMKLRLLNGSHSMLAYAGYLAGFETISDVMTEPAFVALCKKFMDTEAGPTVKTpgFDIEDYKKQLRDRFANPGLKHRTWQIAMDGSQKIPQRLLETLREQLASGGSIEVISLAIAAWFKYVSAVDDAGNAIDVQDPLAARLKSLCDSHPNTSERVAALLGVKEVFGEDLVGCSAFAAAISAWLDAFAKQGVLATIKQ----
4 UniRef50_B2SAL5 Mannitol dehydrogenase n=45... 566 1e-160 1 44.6% 6:485 19:497 -----LPSSVKVPAYDRSRITTGIAHLGIGAFHRAHQTAYTDAVLTSGSNEWGIVGVSLRRPDTR-DALQIQDELYTLAIRDGDSEKLQVIGSIQNIL-VAPEDPQAVLDIMSHPDTRIVSLTITEKGYCRDAAVSGLDRSHPDIIYDLAHPATPRSALGFITEALRRRRAQGTAPFTVLSCDNLPANGETCKNVIVQFAGCTDTDLAHYIEETVAFPSTMVDRIVPATTDEDRISISRTLKVLDQWPITTEPFSQWVIEDRFPTGRPAWEIAGATFVQDVAAFELMKLRLLNGSHSTLAYLGFLAGHRTVSQTMAAPGFKQLIKALMEIEIAPTLplEGFDLSSYQAALIHRFENHALHHLTSQIAMDGSQKLPQRLLNTIQERLDGGGSIDRLALGVAAWMRYVTGKDEAGTPIDVRDPLSGQLLDQTQGKFAPDEIMDALLSFRQIFTARLAANELFREKLRLALGSLYAVGSAETVRRYAE-
5 UniRef50_P39941 Mannitol dehydrogenase DSF1... 550 1e-155 1 39.0% 8:484 22:499 -------STLPIPTYPREGVKQGIVHLGVGAFHRSHLAVFMHRLMQEHHldWSICGVGLMKADALmdAMKAQDCLYTLVERGIKDTNAYIVGSITAYMYA-PDDPRAVIEKMANPDTHIVSLTVTENGYYHSEATNSLMTDAPEIINDLNHPEKPDTLYGYLYEALLLRYKRGLTPFTIMSCDNMPQNGVTVKTMLVAFAkkKDEKFAAWIEDKVTSPNSMVDRVTPRCTDKERKYVADTWGIKDQCPVVAEPFIQWVLEDNFSDGRPPWELVGVQVVKDVDSYELMKLRLLNGGHSAMGYLGYLAGYTYIHEVVNDPTINKYIRVLMREEVIPLLPkpGVDFEEYTASVLERFSNPAIQDTVARICLMGSGKMPKYVLPSIYEQLRkdGKYKLLAVCVAGWFRYLTGVDMNGKPFEIEDPMAPTLKAAAVKGGKDP---HELLNIEVLFSPEIRDNKEFVAQLTHSLETVYDKGPIAAIKEIL--
6 UniRef50_B9JSW9 Altronate oxidoreductase n=... 543 1e-153 1 44.7% 4:484 10:488 ---SANPQRLRRP--DSIRPQTGIVHLGLGAFYRAHGAIYIEQAMEKSGGDWGIIGVSLMRPDQR-DALAPQDFAYTAVELGPNGETPHVIGVINDVL-VARENQRAVIDAMSDPAVKIVSLTVTEKGYCHEPSTGKLNRNHPDIQHDLAYPEAPVSALGFLVRALEKRHAAGLRPFTVLCCDNLPENGKVVRGVVLELAGLISSDLQGWIASEGAFPSTMVDRIVPATKPEDIDRLAQITGVLDLSPVMHEPFRQWVVEDHFVDgrPDLGAVGVELVKDVTPFEHMKLRCLNGTHSSLAYLGYLAGHETIAQTVADPVFARFCKMLWDTEITPGLkpPGISLGDYTAALFDRYANPAIRHRTWQIAMDGSQKLPQRILGTLTENLAANRPITGLALAVAAWMRYVGGIDEKGDAIDVRDPLATRLKSLSDGAAEPAEKVAALLSVREIFPAPLADNPTFRNALTTAYQSLVTKGARQTIEDLS--
7 UniRef50_Q164Y8 D-mannonate oxidoreductase,... 537 1e-151 1 44.4% 12:486 4:480 -----------PPRLQRQNKAPGivHLGPGAFFRAFNAVYTDEAMALNGGDWGILAVSLQSARAR-EELAPQGCVYTSVSMGPEGEETRLVNAISDVM-VAPQNPDAVLRAMARADVKIVSLTITEKGYCRDPSTGGLDVQHPDVQHDLSTPAMPKTAPGLIVKALARRRAVDERPFSVLSCDNLPDNGATTRRIILEFARKRDPELAAWIAQQARFPSTMVDRITPATTPADIDALAQRSGYHDAALVRHEAFRQWVIEDDFVDgrPAWDKVGAQFVTSVTAHEKMKLRCLNGTHSTLAYLGYLAGYETIAETVADASFAALCTTLWHREILPTIPApgEDLQAYVAALLARYQNPAIRHLTWQIAMDGSQKLPQRILGTIADGYAAGRAPDGLCLAVAGWMRYVGGVDENGAAIDVRDPLAARLRAASDSAQSAAGKVDALLDIRDVFDEALASNPDFRRAVHGAYETLVSKGAGGAVADYVAR
8 UniRef50_UPI000197C908 D-mannonate oxidoreductase ... 537 1e-151 1 49.5% 22:486 24:491 ---------------------PRIVHLGCGAFHRAHQALYTHLLFEQFLSNWGYCEINLMsgAVLINQLNKYNGHYTLLEKDEEKSTVRTIKVIKEAMHPRIDGIDAVVEKMASPDTAIISLTVTEKGYCLSPATDLLNLSHPNIQHDIAHPTKPRSVLGYIVASLRLRFQRQQPPITILSCDNIRKNGEAARRAIVGLAAQQDKQLAQWIDQHISFPSTMVDRIVPAMTQESYAEIKQLIGRDDPCAIICESFRQWVIEDNFVNGRPDWQHVGAQFVPDVTPYEMMKLRMLNGSHSFLAYLGYLGGYEFISDAMQNSDYSRAAYSLIINEQAPTLFIpnTTLLQYTQTLIKRFSNKTIKHKTAQIAADGSQKLPQRLLDSIMWHQKHGSDYAFLALGVAAWMKYVSGQDEQGNAIDIKDPLQHKFAEIYHLCGVGLEAVDRLLAINAIFPLEFSQNQDIVKNVKTAYQQLISVGARETVKHYLQQ
9 UniRef50_D2S6P7 Mannitol dehydrogenase doma... 533 1e-150 1 42.1% 4:485 10:490 ---ASLGGSLSVPSYDRSSVRTGIVHLGVGAFHRSHQAMYLDRLMEEGKadWGICGVGVLPSDRRMAemAAQDGLYTLVVKHSDGrdARVVGSVVEYLLA-PDDPDAVVEKMAAEDTRIVSLTVTEGGYNIAAITGEFDPTHPDVVSDLRPGAALRTSFGLVTEALVRRRDRGLAPFTVVSCDNIQHNGDVARRSFAAFAALRDPELGAWVEREVPFPNSMVDRITPATTDDDRAEVARRFGVDDAWPVVCEHFTQWVLEDRFGLGRPPLEDAGVQIVDDVDPYERMKLRLLNASHQALAYLGHLAGYRLVHDAAQDPLFQRFLLGYMEEEATPTlpVPGIDLEDYRRTLIARFSNPHIRDTLARLAFDGSERLPKWLLPVVRDQLARGGEVRRSAAVVAGWARYSEGVDEQGRPIEIADRRRDPLMAAARREREEP---LAFLADRALFG-DLVDDERFTGPYLAALASLHERGARATLEALVG-
10 UniRef50_B2TGB7 Mannitol dehydrogenase doma... 532 1e-149 1 43.5% 9:484 18:491 --------KVVVPAYDRASLAPGIVHLGLGAFHRAHQALYTEHALRAGDHRWGIVGVSLRRADTS-EALTAQDHLYAVDVRDGTADSLQVIGALIASL-VAPQSPAAVLDAMTDPRCHIVSLTITEKGYCRNPASGALQFDHPDIAHDLRAAAAPRSAIGFVVRALALRRAAGLGPFTVLSCDNLPSNGDTMRALTLAFARETDPALADWIELEAAFPNTMVDRIVPLTTDADRLRVAKQLGADDAWPVITEPFSQWVIEDRFAGPRPAWERAGATLVGDARPYEQAKLRMLNGAHSALAYLGSLIGYDTVDQAIGAPAVLNFVESMLRDEVEPTLSRPA--LATYRAELFARFRNTALDHRLQQIATDGSQKLPQRWLESVRANLKSGAPTERLAFALAGWIAYLGGHDETGRTYAIADPLADRLTEAVRahADAADAVRTLFEIEPIFGRDLCAHPRFVAQVARHLAAIRAQGVVKAMDAFA--
11 UniRef50_B6R9L2 D-mannonate oxidoreductase ... 530 1e-149 1 45.9% 4:484 11:491 ---NALPSDVSVPSYDRESLKPRVAHIGFGAFARAHVAMHLHETLAAGGGDWGMRVIELFGTSDLFDKLEENDHLYTLVETADEGTNTRLLGAVCETQHLARDGVEALINGLAEEQLKVISLTITEKGYCVK--NGKLDLDNAMIQQDLSTPSAPKTAIGLIVAGLAKRRALGNGPITVMSCDNLPHNGVLCGIAVREFAAKLDAELAAWIEENVSFPSTMVDRIVPALTDESRELIRESLGGqdLNGIVCEPFRQWVIEDNFKAGRPQWELAGAQLVADVEPFEEMKLRTLNGSHSFLAYLGFLAGKETIADCAADPVFYAEARKLMVDEQLPTLDVPgvDLVAYADSLLKRYSNSKLKHRTWQIAADGTQKMPQRWLNSVRFHLANGGDYRHLVLGIGGWMNYIR-ADRNGESYEVVDPLKEKLAAiaNDGADETTYVDTLLALDSVFPSELVANDEFKKAVHNAYRAVAEKGAAQAVADLA--
12 UniRef50_C6YVN6 Predicted protein n=1 Tax=F... 527 1e-148 1 38.1% 1:485 1:490 MLNLQKLHNCSLPNYQRNNLNPGILHIGIGAFHRAHQVFYINKLLNTGdlNWGYVSGTIRSNQKLIDDLKANDCLYTLSTNDESGTKNTIIGALKDVYFAGNGQSQSLITKISDPNIRIISYTVTEKGYYVDLSTQELNFENPDIAYDLVNINSPKTAIGITVAGLYKRWNKNAKAITLLSCDNMPNNGKILKKAILEFSSKIDKQFSTWVAENVSFPSSMVDRIVPAVTQQTLDNIENMIGQKDISAVATEEFSQWVIEDNFANGRPALEKVGVEFVKDIEPFEKLKLTMLNGSHSLIAYLGAYAGLKTVDEVIVKPEFYNFIKKYMLKIAAPLVdpQEISTSEYANKLLHRFANPHLKHKTEQIAMDGSKKIPQRWLGSLAHLLENKQNYDILALGIAGWILFCSGKDQYGKILEISDPLQNGYKLIYQENTQITDIVNCFLSLKSIFPETIAINNDLKEKIVFFIEEINKYGVIKTLTKLGE-
13 UniRef50_B4WTN2 Mannitol dehydrogenase ross... 526 1e-148 1 37.5% 7:486 36:526 ------PQQVRIPRYDRASITASVVHIGVGGFHRSHQALYIDNYIEKATEnwGICGVGLLKYDEKMRnlQSQDCLYTLVERSSKQDTARIIGSITEYLFA-PEEPQAVIDKLADETCRIVTLTITEGGYYVIEGTGEFDSQHPNIQHDLQFPDQPASVYGFLTAALKKRWQQGLPPFTVLSCDNVQGNGNIASKMLSAFAKLQDPDLEQWIAENVTFPNSMVDRITPATTPADIQMVAEQFGIEDRWPVVAEPFIQWVIEDNFCAGRPRWESVGVQMTDDVHPYEMMKLRLLNASHSLLGYLGSLLGYTYTSEAMEDNLIRRAIAQLMDEVTPTLLPLPNVDIEDYKTTLIERFSNPKVRDQLSRLCLNGSDKLPKFVFGSLQDKLAQGGSIKHLSFVVALWFRYLNGKDEQDQPIAINDPLSDLLTNRAKAGGPDPTQ---LFAITTLFGS-LSKHPSVIDTVTYHLQQLYALGVEKALVELLTE
14 UniRef50_A6WFS9 Mannitol dehydrogenase doma... 526 1e-148 1 40.8% 6:485 20:494 -----LPADVAVPGYDRSALRPAIVHIGVGGFHRAHQAVYLDDLARTGETGWGLVGVGLRSPE-MGQVMADQDRLYLLVERGDDADRARVVGVVDRYLFA-PDDPEEVLRTLADEETRLVTLTITGTGYRIDPHTGEFDADDDDVRADLADPAAPRTVFGFLAEALNRRRRAGLVPFTVLSCDNVPDNGAAARTAVASFARLRDPELADWIEAEVAFPGSMVDRITPTTTPEERDAIAAATGVDDRWPVITEPFTQWIVEDSFCNGRPPLDRVGVQFVEDVAPYKAMKTRMLNASHCALAYLGILAGFSTIDEVLADDTFRAYLEHLMDDEIAPLLPppGVDLEDYRRSLVRRFSNPKMGDQLGRLGRRGSTKMPDYVFPSVSAAIEAGRPHQLLLLAVAGWMRFLRGYDYAGNDVPVSGPLSERLVELAREGLTEPE---ALLTERSVFG-GLGDDAGFVAGVEVALRALEEQGPREVIALYLG-
15 UniRef50_B2TDP7 Mannitol dehydrogenase doma... 523 1e-147 1 41.4% 18:483 28:495 -----------------QEPRIGIVHLGIGNFHRAHQALYTEEAMLAAGGDWGICGVTLQGDVGKRDALMEQQGLYSVVERGPHGAKVTVVRALREVLAMPHDQ-AALFARLADPAVRIVSLTVTEKGYCRDPRTGEVALDNPAVAHDLASPFEPRTVPGILVAALRQRHdaRGQPFTVLSCDNLSHNGAALRQVVCSFARQLDPALADWIAAHVAFPSTMVDRIVPATTHAESVTVAHAIVYQDAAPVPCEPFRQWVIEDRFPAGRPAWDAVGAQLVDDVTPFELAKLRMLNGTHSTLAYLSMLGGFETIDAAISYPPMRNLIHAMMTEEIAPTLTMpsFDLSAYRDALLERYANPALKHRCSQIAMDGSQKIPPRLLDTIAARIDAGQSFTRLVLAVAAWMMFLRGHADDGTRYEISDPLASRLHALasAHDDPQALMDALLSVREVFPADLTAFPEFREALLRALRLLREEGARGAIAAL---
16 UniRef50_Q21L96 Mannitol dehydrogenase-like... 521 1e-146 1 40.2% 1:483 11:489 LSNVLDP--VKKPQYTPSEHRSGIVHIGIGAFHKAHQAVFTDDVLNMHGGDWRITAVSLRRPDAR-DQLEKQNSLYTVVEKSDGEISPRIIGAVEKVL-VCPEDPQQVINTIASTDIKIVSLTITEKGYCQK--NGTLDTSNVDIAHDLNNLSAPKSMPGLIVAACAARKQNNANGFTVLSCDNLPHNGKITQNVVMRFAEKVDAELASWIATHISFCSTMVDRIVPATTSADLDEVKNLIGLADDAAVICEPFRQWVIEDNFVAGRPQWEDAGALLVADVTPYEDMKLRLLNGSHSALAYLGFLSGFDFIHQAIANPRLLALTKKLMDEDVTPTLNVpgFDLDAYKAIIRTRFANSRVPYKTTQVANDGSQKLPQRILAVADHLISGGKQPAVIPAIIAAWFQFLEGQDTHGEQHTVNDPLANTLCPLakHKANDTKQVQELVAASQIFPEGLIANTEFINSIEHYLAKFHAKGVLTTLAEL---
17 UniRef50_C5CMZ2 Mannitol dehydrogenase doma... 519 1e-145 1 41.5% 4:482 10:503 ---AALPPAVARPAYDRAALEAGIVHLGVGAFQRGHLAAVNEAALHagDLRWGIAGVSLRSPDTR-DALAPQDGLYTLTLRDVDEasLQVLGCLLGV-QVAPEDPAAVLARIAHPATRIVSLTVTEKGYCHDPATGALRADHPDVLHDLARPDAPRGTLGFVVSGLRLRQLRGLAPVTLLSLDNLPSNGHLLRGLVLDFAQRVDPQLARWIAEHCSFPCSMVDRIVPRTTDADRAQVDAALGLEDAWPVVGERFLEWVVEDDFAAGRPAWDAGGARFVPDARPFETLKLRMVNGAHSALAYLGAMAGLDTVDRAVATPALHRYLDRLMREEIAPTLplPGLDLDAYRQRLLERFANPALAHRTAQIAMDGSQKLPQRLLGTVRERLAAGASIDRLALAVAAWLHYLRGIDELGRRHEIQDPLADAlaAAAEPAQADEARVAVFAAFAPVFGNDLGSNPRFVSAVATQLRALRELGVHKTLAD----
18 UniRef50_B7UIR8 Predicted mannitol dehydrog... 518 1e-145 1 48.5% 11:484 14:485 ----------QVTTWPRGGLQADIVHIGFGAFHRGHQAVYTDLTNQLSDTRWGIFEINLFGDAQLIENLNAQNGLFSVVETSASQSTSRLVRSVAGGIHTPRDGIAAAIHKLAEPQVKIVSLTITEKGYCLDPQTRSLDLTNGLINHDLQNPDAPQSAIGVIVCALQQRKAAGLAAFSVLSCDNLPDNGHLTRNAVLGFARQLDQPLAQWIEENVSFPGTMVDRIVPAMTESQFALLETKTGYADPCGIVCESFRQWVIEDNFVRGRPEWDKAGAMFVSNVQPYEEMKLRMLNGSHSFLAYNGSLAGYEFIWQCMEDADFRSITRQLMINEQARTLNPdnIDAQEYADLLIERFSNRNVAHRTGQIAMDGSQKLPQRALTPWLKLHQQKQNNAVLSLLVAGWLHYVIDAVEKSQ--SVADPMNDQLQALIKEQQDAWQQALALLHLSAIFG-DLSNHQPFINEIKIAFANIKNKGIKATISQLL--
19 UniRef50_Q742F6 Putative uncharacterized pr... 518 1e-145 1 37.3% 1:482 21:500 LSNATLpqRIDVPTYDRSALQRGVVHIGAGNFHRAHQAVYFDDLACSGISdwGVSAISLRSHDVK-DLLSAQDGLYTVVQRGHDHQTARVVGSIGSVHYAPNDG-AAVRAALTDPRTRIVSLTITPNGYFLDPVTREFDADHPDVRADLVASGCYGTAWGYLTEALEQRRRAGIAPFTVLCCDNIPDNTQAARTALVSFAALKNPGLARWIDRHVAFPSTMVDRITPQTSDSEREFVERTFGVADNWPVLTEPHSQWIIEDAFSDGRPPLDEVGVQFVTDVSDHKLIKTRLLNGTHIALACLATLAGYRRTDEAMKDPVIFDYVERLMRDEVQPLLPppGMNTPDYRDTLLTRLGNPRMSDQLSRLARRGSTKIASFLLPSLHEAIAQDRPHTLLMLALAGWARYLRGYDLNGRKIRIDDPEADLLTKLANMAGNNPD---PLLRHEIL--ADLRLVPGFSERLGEMVASIDEHGVIATLRQ----
20 UniRef50_Q1NAI9 Putative D-mannonate oxidor... 517 1e-145 1 40.7% 6:486 12:489 -----LPHDVRRPSYDRAAVRAGVVHLGIGAFHRAHQAAIFEEALNAGDLRWGIIAASLRSPAVR-DQMAPQDGLYTVLVRDGSADRAQVIGAVRQVI-VAPEDPEALLAALAAPDTHIVTLTVTEKGYKLDPATGGLIEGDAQVAADLVSLKAPQTAPGYLVAALARRKKEGLTPFTAISCDNLPHNGQRLRGAVLDLARRHDPALADWIAAEGAFPETMVDRIVPATTADDVAALGRRLGVEDQAMVKTEPFLQWVIQDWFCGPRPTF-GAGVQVTAAVAPWEEAKLRLLNGAHSGIAYLGGLAGIDHVHEVLTLPEARAFVEALWDEAEATLTPPPELDVAAYRRDLMARFDNPTLRHRTRQIAMDGSQKLPQRLLAPIAARLEEGQGVDALSLAVAAWIRWQAGVDDQGAGHVVDDPLARPIAEALSGASDSRGRVDAILALGAIVPPKLAEHAAWRETLMKWLSVLETHGARAALAKLRSE
21 UniRef50_A6VZ13 Mannitol dehydrogenase doma... 516 1e-145 1 40.1% 15:480 11:481 --------------YAPEKVDVGIVHIGLGAFHRAHQAVYIEklNRNQGGEWGICAVNIRSNSQLVDELKANGCRYHIAeqDSQNVELREINAIRDALFAGAD-KEPLFEKLMSPKTKIVTLTVTEKGYYLAPADKTLRQDDPSIQHDIQNPTAPKTAPGILVEALYRRKDLGLPPFTILSCDNMPNNGSLTRRAVCELAAHRSAEFAQWIEDTVAFPSSMVDRIVPAMSDDSRERLQKELNCHDQNAVMCEAFSQWVVEDNFPQGRPDWEHDGVQMVKDVHPFETMKLRLLNGSHSLLAYVGLAAKYKTVAQAVADEKFAALIRHYMSVEAAPTLDLpeVKVHEYIESLISRFANDSLQHQLSQIAMDGSQKIPQRWLNGAEERLANdgDLNATALGVAAWLFYVRGEDLEGNQHKVDDPMAQALRELHGRCFDPESLVREAFKLNDIFSTKLSQSEMFSSAVLSAYQLLISSGVTECL------
22 UniRef50_D2SB75 Mannitol dehydrogenase doma... 513 1e-144 1 40.8% 8:475 47:510 -------ARIAVPTYDRAALTPSVVHLSVGGFSRAHQLIYFDELAERrsTGWGVVGVGLRQRH-LQDALAPQDHLYTVVERSPDGERARVVGVMVDYLYA-PDDPAAVLDRLSDPRTRLVTLTITPDGYLLDPQTRAFTADHPDVLRDLAEPHAPATVFGYLVEALDRRRKAGLAPFTVVSCDNLHRNGEAARASVVGLARLRDEVLARWITDGVAFPSSMVDRITPQTPPEERAALAARYGVDDRWPVVTEPFSQWFVEDTFSHGRPPLDEVGVRFVPDVGDYELMKTRLLNASHSALGHLGSLAGYDRMDELMGDPVFATYVERLMDDEVTPLLPQpgVDLADYKRTLLQRFANPAIADRLSRLCRRGSAKLPQHLLPSLRQSLVEGRPAPLLLLAVAGWCRYLRGTDDDGRPLPLEDPRADELRALALAGGGDP---RPLLGVRAVFG-DLGDDPVVVAALTGAIETIDRLG-----------
23 UniRef50_A6W5I3 Mannitol dehydrogenase doma... 512 1e-143 1 43.6% 11:485 30:509 ----------HRPRVDPRALGVGVVHLGIGAFHRAHQAVYTEDAVAAAGGDWGICGVTQRSRSV-VEQLGPQDGLYTVLAHDAGGSSARVVGAVRELLFAG-EEPGRLRALIAAPTTRLVTLTVTEKGYRHDPATGRLRRADPDVAADlsTARPPRTVVGQLVAGLAARRAADAGPVTLLSCDNLPANGAVLRGLVGDFCAALPDglREWIAASVRFPSSMVDRIVPATTPADRDQVQRLLGLRDEGVVVTEPFRQWVVEDDFAAGRPAWERAGAVLTADVAPYEAMKLRLLNGSHSTLAYLGLLAGHEHVADAVADDGIAALVDRLMAHDVVPTLAVpgFDVARYRQDLLDRFANPALHHRTLQIAMDGSQKLPQRLLGTISDALAAGREPRAACLGVAAWMRYvtGRSEAGVALPVDDPLAARLGEVTAGAGSPAAVVDALLGLPEVFGTDLPADARFRALVEEALEVLTRDGVAGAVRESVA-
24 UniRef50_Q3ID77 D-mannonate oxidoreductase ... 509 1e-143 1 36.6% 4:473 20:489 ---AQLPSHVDTPSYDRSAVKAGIVHIGVGGFHRAHQAVYVNELLkpGSEQWGICGVGLLEGngLRDILKQQDYLYTLTVRHPDGkdNKVIGSMIDFLFA-PEDKQAVINKLAHSDTKIVSLTITEGGYNFNPATGEFDYSNPDIINDINNPNDPITAFGYITAALKLRKEQGLGAFTVQSCDNIQHNGNVTRKMLLAFATEQDKNLSEWIEQNVSFPNAMVDRITPVSKKSDIDYVVDAYGVSDEWPITCESFTQWVIEDTFSDSRPNWDVVGAQFVTDVTPYETMKIRLLNAGHSVLGLLGSIHGYGTIDETVSDELFATYLRAFMDKEVTPNlpLEGIDLQSYKDTLIERFANPNIKDSLARICSESSAKLPKFLIATINENLVQGRDVSLATLVIATWCLydKGVSEKGEKLEIQDAMYKELNSYAQETQTSP---IAFLKLTSLFGK-LEHNETFTAEYKKSIAALYA-------------
25 UniRef50_B5ZVY4 Mannitol dehydrogenase doma... 502 1e-140 1 44.3% 6:474 11:479 -----LAPTAKLPAYDRSRLKSGILHLGPGAFFRAHFAPFTDGALAADGGDWGIEVASLRTADV-ADNLSAQNGLYTTLIRDTSGTTAEVIGSILKA-HVAPRDPAGLLARLEDPDIRIVSMTVTEKAYGFDPATGGLDLKHPDIVADLANRHAPRGVIGYLVEGLARRRQKGIAPFTPLSCDNLPSNGAVLKRLVLEFTSRIDADLHRWIEANVPFPSTMVDRITPASTDATYADAERLTGRTDMAAIETEPFTQWVIEDHFANGRPAWEKvgALMVEDVSAYEKMKLRMLNGAHSLLAYLGYIGGYEFIRDVMDDAALAALAYRHMHAAARTLDPVPGIDLDDYANELIARFANKAIAHRTYQIAMDGTQKLPQRLLEPACEALAHGDRAETFAIAVAAWMRYALGEHGNGERYELRDPRAAEIAALIADvrTGPAISAALFALPGLFPSALTGHRAWTQDVSDKLEILIQD------------
26 UniRef50_C8WEY9 Mannitol dehydrogenase doma... 502 1e-140 1 35.6% 4:483 20:503 ---NLDPKRVKIFKYDRSKVTAGIAHIGVGNFHRAHQARYIDDCLapGNESWGIVGISLGdsKAKAKAMKDQDCLYTLTEYDAKgpSTRIIGSIIQYLHA-PEDPEATMAMLVDPAIRIVSMTITEGGYHLD-SEGNFQSDAEAVQADLKDPEHPKDTFGYIVEALARRRKAGTEPFTVFSCDNQRGNGDVAKQAVLSFARLRDPELAEWIEKNVSFPNSMVDRIAPTVTEEEAEAVRKLTGIDDQSPVIAENFLQWVIKDEFCNGRPPFEKVGAEFTQNVAPYEHMKGRMLNASHTAIALPGVVAGYEYVHEALGDPEIHRLVYDFMTKDVIPVTKGpgISLTDYRDMVLSRFSNPALKDQLVRIAGDSANKLPTFLLPTINEHTEdsRDLRRMAFILACFRRYLRGIDDKGHKFTPIEPHISKEERAEWGSENT----EGFLNCRILESLGLADNEAFVKAFNHAVSLLKPQGVLGALRHL---
27 UniRef50_C5PU77 Mannitol 2-dehydrogenase n=... 499 1e-139 1 32.1% 9:481 2:474 --------KVHTYNYDRNTIQSGILHIGVGNFHRAHQAFYTDQLLHDEDqqWGICGACLLPGdkLVQNLRSQQLDYTLTVCGREGedIYRIGSLSELLWA-VEDQQELLHKIADSAIRIITLTITEGGYNLDKVTNEFMLDNEWIKDDLIHPANPTTVFGYIAEGLRQRKASGSGGITILSCDNLQHNGNTAKRAFCTFIAAQDPELAEWMETNVSFPNSMVDRITPATTAQDITRLNNQSGIYDKAPVYCEDFIQWVIEDNFIAGRPAWERVGVEFTDDVTAYENMKLSLLNASHTLLSYPSFLIGYRKVDEAMQDKEMVKFVCDFMDTDITPHVPPpgIDLKEYKQTLIERFANPAVSDQISRLCFDGISKFPVYIMPNLLKMIKDNQELSRVAFLIASYRHYLkqTDDKQQQFEIAEPWLTAEDRESTKSNNPVD----FLRLSAFRSTDLTAVASFVGLYTGFAHSIREKGLKKVLQ-----
28 UniRef50_A1WNS1 Mannitol dehydrogenase, C-t... 499 1e-139 1 40.7% 6:484 12:509 -----LPASVARPGYDRDALKTGIVHLGLGAFPRAHLAAVNEAALHagDLRWGIAGVSLRSPDTR-DALAPQGGLYTLALRDIDDsaLQVIGCLRQCL-VAAEDPAAVIALIAHPDTRILSLTVTEKGYCHDPASGALQVQHPQVQHDLAALDRPCSTLGFIVAGLRQRRRLGLAPVTLLSLDNLPSNGHLLRALVLDFAARIDPALADWIAGRCSFPCSMVDRIVPRTTDDDRALVRAALGVEDAWPVVGERFLDWVLEDRFVAGRPAWERSGARLAQAAQPFETLKLRMVNASHSALAYLGLMAGFQTVDQAIAQPALRRYLERLMTEEIAPTLplAGLDLHAYRERLLARFANPALAHRTAQIALDGSQKLPQRLLGTVRDRLAAGASIELLALAVAAWLHHLRGRDEQGQPYRIHDPQADALAQQHAlhQATSAWVRTFSGLAPVFGTDLQHSQPFVHAVAAQLHALRTRGVLPTLEGLA--
29 UniRef50_A9CFC2 Mannitol dehydrogenase n=1 ... 499 1e-139 1 36.0% 6:486 13:489 -----LPQDVLLPTYDREAVTPGIVHLGVGAFHRAHQAVFIDDCLARGETGWGIVAASLRSPDTR-DAIAPQDNLYTFCLRDGENETLRIVGSILETI-VAPEDPERLLRAMTDPRVRIVTLTVTEKGYLADLSAGTLLRDHPDVVHDLAHPQKPRSALGFLLEATRRRRVAGAVPLTLLSCDNLPSNGRILRRLLVEMAGLTDKDLAEFITENLSCPCVMVDRIVPATTATDRERVTVRLGCEDAWPVIAEPYFRWVIEDRFPHGRPGIELSGAEIVDDVEPYEHMKLRMLNGAHTAMAAIGQCSGLETIADIYADPRVRGYIDRYWREVGSTL--SPAVSGPDYVTGLRQRFANPALRHRAAQIASDASQKVPQRILAPLAELRAAGAPDAAALFAVALWIRSCATLNERGEAIVMADPAFAEWAVPTGNGEEPDAVIDRFLTFRRVFGPEWLADEAFVTALRAAYRDIVQYGALGAIERHFSE
30 UniRef50_B9JJF8 D-mannonate oxidoreductase ... 496 1e-139 1 40.3% 10:471 15:467 ---------IESSTYDRPALKPGIVHIGLGAFHRAHQAVYTDTALAHAFGNWGIVGVSLRSTE-IAQDMRVQDCLYSVVACDRFGDSVRVVGSIVEAL-AANEDGEAVLARLADPAIQIVTLTVSEKAYGIDPVNGGLDHAHAAIAQDLKSPTRPMGVIGYLTEGLARRLSAGLPPFTVLCCDNLPSNGRIVRRLVIEMAATRDPALAEWVSETVSFPCSMVDRIVPAATAETRARAEKLLGVEDRLSIEAETFSQWVIEEDFVGGRPAWEAGGALFVENVEPYEKMKLRLLNGSHSLIAYLGQLQKLEFVRDVMAIPENVALVRRHMQAAVRTLDPVPGIDLTHYMDQLVERFANPAIAHRTQQIAMDGSQKLPQRLFQPAVDAISSGSDAAEFAFATAVWIAYLKQAE------TIDDPRGRELQRAAADA-TPADEAASFFAMAGLFPSELQANRAWRDQVNSLLRSL---------------
31 UniRef50_C7GXF5 Dsf1p n=1 Tax=Saccharomyces... 496 1e-139 1 37.1% 8:484 22:466 -------STLPIPTYPREGVKQGIVHLGVGAFHRSHLAVFMHRLMQEHHldWSICGVGLMKADALmdAMKAQDCLYTLVERGIKDTNAYIVGSITAYMYA-PDDPRAVIEKMANPDTHIVSLTVTENGYYHSEATNSLMTDAPEIINDLNHPEKPDTLYGYLYEALLLRYKRGLTPFTIMSCDNMPQNGVTVKTMLVAFAkkKDEKFAAWIEDKVTSPNSMVDRVTPRCTDKERKYVADTWGIKDQCPVVAEPFIQWVLEDNFSDGRPPWELVGVQVVKDVDSYELMKLRLLNGGHSAMGYLGYLAG--------------------------------SVDFEEYTASVLERFSNPAIQDTVARICLMGSGKMPKYVLPSIYEQLRkdGKYKLLAVCVAGWFRYLTGVDMNGKPFEIEDPMAPTLKAAAVKGGKDP---HELLNIEVLFSPEIRDNKEFVAQLTHSLETVYDKGPIAAIKEIL--
32 UniRef50_D2U8Q2 Putative mannitol dehydroge... 495 1e-138 1 36.4% 4:484 11:484 ---HTLPLAITRPSYALDRVRIGIVHLGAGAFHRAHQAVYLDDLL-ASEPDWAISAVSLHNPQVR-DALCAQDGLYTLALLDAQ-PELRVIGAIREVLCAQ-DQQAAVLARLTDPAVRLVTLTVTEKGYCL--TGEHLDLAHPDIAHDLAAPHAPRSAIGYLVAGLRQRWRLRLAPYTVLSCDNLHDNGGKLRRAVLRFAHHIDPALAAWIEAEASFPRSMVDSITPASDAALRERIATQLGYDDAWPIQRERYSQWVIEDRFCNGRPAFERVGVTLSEDIGGFDRAKLRLLNGPHSALAYLGTLLALETVADAMCDTPLATFIETLMREDITPTLplSGFDPQRYIDAILTRFRNPAIAHKLAQIAWDGSQKLPVRLLGTLADALAAGHRIDRLCLPLAAWMHFVR--HQAHRDVPLIDPLQETLREIGRAAGSDdqDVDAFLTLDTVFAP-LSKDRRFVDALQRAYASLGDGSAAETRETLV--
33 UniRef50_Q3BME4 Mannitol dehydrogenase n=13... 493 1e-138 1 37.2% 4:471 30:490 ---ATLPPVVSRPSYDPASPTIGIVHLGAGAFHRAHQAVYIDDLLAE-DPSWAISAVSLHRPQVR-DALRPQHGLYTLALLD-EHPHLRVIGAIREVLCAA-DEHAAVLARLADPAVRLVTLTITEKGYCL--AGDTLDLSHPDIVHDIAHPARPRSAIGYLVAGLQQRRHDGTAPFTALSCDNLTDNGMLLQRAVVRLAEQTDPALAQWITQHAAFPRSMVDSITPATDDALRTRVHDQLGVHDAWPIQRERYSQWVIEDRFCNGRPAFERVGVTLSEDIAGYARAKLRLLNAPHSALAYLGSLLDLETVAEAMRHRELAAYVETLMRAEIAPTLqmQGFDAQRYSDAILARFRNPAIGHLLAQIAWDGSQKLPVRLLGTIGDALATGRPIQRLCLAVAAWLHFVRRQAHNG--VPLTDPLNDVLSALGRNagDAGHDVADFLTLEAVFGS-LPADARFRASLQAAYAAL---------------
34 UniRef50_Q8NU38 Mannitol-1-phosphate/altron... 493 1e-138 1 36.9% 5:486 16:500 ----ASTSGVQIPAFNRADVAPGIVHFGVGGFHRAHQAMYLNELMNEGklDWGIIGMGVMPSDVRmdALASQDHLYTLTTKAPDGtdQKIIGSIIDYVFA-PEDPARAVATLAQDSIRIVSLTVTEGGYNIDPATEDFDHTNPRIVADREALQalQTFFGLITAALISRKESGSTPFTIMSCDNIQGNGDLAKRFFLAFAHSVSSELGEWVENNVAFPNSMVDRITPETTDGDRDDI-KEIGYIDAWPVVSEDFTQWVLEDAFTQGRPAYEEVGVQVVSDVEPYELMKLRLLNASHQGLCYFGHLAGHHMVHDVMADTRFQDFLLAYMEREATPTLklPGVDLDAYRRQLIARFGNAAVKDTVPRLCAESSDRIPKWLLPVVRENLAAGRDVTLSAAIVASWARYAEGTDEQGNPIKIVDRLSERVQENASGNRTD---ILSFIRDRGIFG-DLVDAEPFTKAYSETLSSLHDRGAEATIDALLTQ
35 UniRef50_C8SUD3 Mannitol dehydrogenase doma... 492 1e-137 1 40.9% 5:483 22:504 ----ALPASVATPSYDRGRITPGIVHLGVGAFHRAHQAAYVHDCLTAGETDWGIIGVSLRSPDTR-DALAPQDGLFTLAIRSSGEEELRVIGSIGSML-VAPEDPGAVLAALSDPRTRIVTLTITEKAY-LRAAGGGLDAAHPDIVHDLANPQGPRTAHGFLTEALARRRAAGTPPFTVLCCDNLPANGATLHRLLIEFAELRDarLAGHIADEVAFPSSMVDRIVPATTDADRARIAVELGVEDAWPVMTEPFRQWVIEDNFSAGRPAWEKFGVTMVGDVAPYEDMKLRLLNGAHSGIAYLGLLSGHATVDRAFADPAIRQFVDALW-AEAIPTLPEdgLDTKTYTAELAERFSNTALAHRTAQIANDGSQKLPQRIVASAVECMEAGTEFVHLTLVVAAWIAACAARGKTLPEGHFTDPLDGPLTALLSEQLPANETVTAVFDLAG-FAKDHAERQTLIGLVAVHLVHLRRDGPTLAFAAL---
36 UniRef50_A0R3S3 D-mannonate oxidoreductase ... 489 1e-137 1 35.8% 9:483 22:476 --------TIPHPSYDRAKVQIGIVHFGVGGFHRAHQAMYVDKLLEMGlsEWGICGVGLLANDRRMAemEAQDGLYTLLLEHPDGheARVIGSIVDYRYA-PDDQEGVIELLAAPTTKIISMTITEGGYYIDSA--------PEI-----------NVFGLVTEALVRRRDRGIGSPTIVSCDNIEGNGDVARKAFTTYAERVHPGLGEWMSANTRFPNSMVDRITPVTTPEVISTVEREFGVADQWPVVAEPFTTWVLEDSFSDGRPPYEEVGVMVVDDVTPYELMKLRLLNASHQALCYFGYLAGYRLVHDAASDPLFADFLLAYMDSEATPTlpVPGIDLDEYKHTLIERFANPGVRDTIARLCYGSSDRIPKWLVPVIRENLKTGAPIRLSAAVVASWARYAEGVDEQGEPINVEDQLADTLVPIALSQREHPT---AFIENTEVFG-DLASSQRFVDEYLWALDSLHRHGARATLESL---
37 UniRef50_C8SWP0 Mannitol dehydrogenase doma... 489 1e-136 1 38.1% 1:486 8:497 LGPALlpVSVQTPAYDRAALAPGMAHLGVGAFHRCHQAEYTDDLLSLQFDRWGVVGINIRPPS-LAGTLGRQSGLYTRLIRENSHVEARVIGSIVKVVDSQ-ESAKPALDVLASPDIDLVTMTVTEKGYCHIPSSGELDLGHPDIVHDLTNSQAPRSVPGILAQALEQRRATHGQPMTLLSCDNIPTNGVILEKVVRTFAERRDKGLADWIAANAAFPCAMVDRIAPAVTRDDLDSVEQWFGYRDDAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGAQTTLATLGVLAGLEHTFDAVADPLLLAFVRRMLIQETLPTlpVPGVLPLAYVEQSLGRLQNTAIRHRNHQIATDGSQKIVQRLLNPIRDRLRQGASIGLLSVPVAGWMAYLIQASArgKRWPVSDPYAGKVAGIADtgRDAPALASGILAIDGIFDPGLAANETFRAAVTSALDDLLSDDPMAAVRHSLEQ
38 UniRef50_P80354 Polyol:NADP oxidoreductase ... 485 1e-135 1 37.5% 6:480 10:483 -----LPANVQAPPYDIDGIKPGIVHFGVGNFFRAHEAFYVEQILEHA-PDWAIVGVGLTGSdkKAEEFKAQDCLYSLTETAPSgsTVRVMGALRDYLLAPAD-PEAVLKHLVDPAIRIVSMTITEGGYNINETTGAFDLENAAVKADLQNPEKPSTVFGYVVEALRRRRDAGGKAFTVMSCDNLRHNGNVARKAFLGYAKARDPELAKWIEENATFPNGMVDRITPTVSAEIAKKLNAASGLDDDLPLVAEDFHQWVLEDRFANGRPPLEKAGVQLVDDVTDWEHVKIRMLNAGHITLCFPGILVGYENVDDAIEDKDLRGNLENYLNKDVIPTLkpPGMTLEGYRDSVISRFSNKAMSDQTLRIASDGCSKIQVFWTETVRRAIECKRDLSRIAFGIASYLEMLRGRDEKGGTYESSEPTYGEAQKKLAKADD----FESALKLPAFDGWRDLDTSELDQKVIALRKVIREKGVKAAI------
39 UniRef50_Q15XM6 Mannitol dehydrogenase-like... 482 1e-134 1 34.5% 8:471 18:479 -------KGINVPQypPSAAKIGIVHIGPGAFFRAHQAWYTHQALKRHGGDWCISAVSLRSS-GVSDALTAQNGLYCLAELDKD-TNFEVVGSIKEVL-VARQQYADVIARLIHVDTKFVTLTITEKGYCLN-NQGELDLAHADIQHDLKVMTERVSAVGILVEALSIRHDKGLPAFTVISCDNITGNGGKLKNALVSFAAQCNLTLATWLADSITCPSTMVDSITPATDDALRELVQQTLSIKDNWPIKREAFLQWVIEDCLPSDRPAWEQVGAVLTQDVEGFERAKLRLLNCPHSSIAYLGCLLGIETVYDAMQHTQLVAFIESMIQEEILPSIEGpeLDAKQYSQDILQRFRNPAIRHLLSQIAWDGSQKIPMRILPIIQQNLREGRSVRLLCYALAAWMQFVRLQFSKGET--LVDPLAAQLETLcsCNGEAQHDVGLFLSMSAIFPLSLATDGDFNSGLQAAYTNL---------------
40 UniRef50_D1N0Y6 Mannitol dehydrogenase doma... 480 1e-134 1 30.9% 9:484 3:478 --------TVEKFKYDRRNVKAGIAHIGVGNFHRAHEEYYTDLLLepDQHNWGICGIALLPSdkLVEALRGQRGEYTLTVCGRDGRDQalIGSLVELL-WSVEDPGAVIAKLADPAIRIITMTITEGGYNLDKSTGEFILANEGVQHDLKHPAAPSTVFGFVAAGLRRRMESGGGPVTILSCDNLQHNGSTARRAFTAFFEAQDTALAGWVAANVTFPNSMVDRITPAVLPADRERLNASNGTDDAAPVYCEDFIQWVIEDKFAAGRPAWERVGVEFTGDVTAFENMKLSLLNASHTMLSYPAFLTGYRKVDDAMHDERFARYLRDFMDKDITPYVPAPgvNLDEYKQTLIERFGNRSVSDQLARLCFDGVSKIPVYIMPNLGKMLRDKADLTRVAFFAAAYRRYLkgTDDNGAPYTVDEPWLTEEDRKLIASADPDV----FLGLSPFASVDLRGDARFPVLYRKMVKELEEKGVSPVLEAVL--
41 UniRef50_Q98JL8 D-mannonate oxidoreductase ... 479 1e-133 1 38.6% 4:482 3:482 ---DQLPAAVRTPGYDRTTLAPGMAHLGVGAFHRCHQAEYTDDLLARQFDRWGVVGINIRPP-TLADTLGRQSGLYTRLIRENSHIEARIIGSIVKVVDSQA-SAGPALTVLSSRDIELVTMTVTEKGYCHIPSSGALDLGHPDIVHDLANPHAPRSVPGILARALELRRATHGRPLTLLSCDNIPANGVILETVVRSFAERRGNGLAEWIAANAAFPSAMVDRIAPAVTQHDLDSVEQWFGYRDAAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGTQTTLATLGVLAGLEHTSDAIADPLLSAFTRRMLVEETLPTlpVPGMDPSAYVEQSLGRLKNTAIRHRNHQIATDGSQKIVQRLLNPIRDRLRLGQTIGLLSVPVAGWMAYLIQadRFGKRWPVSDPYAGKVAEIADagRDAPALASAILAIDTIFDPGLAANAAFRAAVTSALGELLSDDPMAAVRH----
42 UniRef50_C6XQI5 Mannitol dehydrogenase doma... 477 1e-133 1 34.3% 6:471 17:473 -----LSSGVRCYDYDRDSLPVRVVHFGAGAFHRAHQLDYFDRLN-AIDPNWGVCSASLRSAKVK-DALEPQDGLYTLVVLD-DVIEYRIIGTLKSVVLAK--DPE-FIERLTAPETLVVTLTITEKGYCVT-ADGQLDVENPDIKRDLATPSSPVSAIGWLALCLSIRMERGLNGLNIVSCDNLSGNGEKLRAAVLGYVQHTNPDLVSWIESNCFFPNTMVDSITPATDESLLGRVQDAIGLNDEWPIQREAFTSWIIERNVSEDFPDLAKVGVTFTSDVAAHESAKLRLLNGAHSSLAYIGLLCGHETVYKGMSDPDVMTFIASLMRDEIAPSVNVpgMDIEAYINSLISRFQNPEIEHLLSQIAWDGSQKLPFRLFQTVQDNIGAGRSISKLCMGICAWMEFVRRQAISGT--QLVDPKDKELRALA-LASDGKNYAEKFIRESGVFPASLRENTIFLENINNSYASL---------------
43 UniRef50_P33216 Mannitol 2-dehydrogenase n=... 476 1e-133 1 37.1% 6:485 1:476 -----MTRSVTRPSYDRKALTPGIVHIGVGNFHRAHQAVYLDDLFALggHDWAILGAGVRPTDARMRelAAQDNLSTVIELDPAGHRARQVGAMVGFLPVEADN-AALIEAMSDPRIRIVSLTVTEGGYYVD-ASGAFDPTHPDIVADAAHPARPATAFGAILAALRARRDAGVTPFTVMSCDNLPGNGHVTRNAVVGLAELYDAELAGWVKAQVAFPNGMVDRITPATGPHERE-LAQGFGLADPVPVTCEPFRQWVIEDHFPAGRPALEKVGVTFTPHVHAYEAMKIRILNGGHAVIAYPSALMDIQLVHAAMAHPLIAAFLHKVEVEEILPHVPppDTSIPDYLTLIESRFSNPEIADTTRRLCLDGSNRQPKFIVPSLRDNLAAGTVPKGLVLLSALWCRYCFGTTDSGVVVEPNDPNWTALQDRARRAKETPA---EWLAMTEVYG-DLAQNDLLAAEFAAALEAVWRDGAEAVLRRFLA-
44 UniRef50_D0XNS1 Mannitol dehydrogenase doma... 472 1e-131 1 36.6% 6:480 14:480 -----LPEGVAGLTYDPSRITAGIVHLGPGAFHRAHMAHYVHAQMSRGqmDWGIIGAGLTSFDARVRelAPQDWLYTLVERDDQGASAQVVGSIVEVL--PPVGTGAILDAIDRPGIRIVSLTVSETGYCLDATTRRLDRTNPLIASDLAHPRQPGSVIGLLVEACRRRRDAGRPAFTALSCDNLPGNGGLLRAAVLEFAAQVDPGLGDWIATHARFPATMVDRITPVTRPEDVAMLTRTWGLNDGWPIVCEPYAQWVIEDDFADGRPDWEAVGVQFTADVAPYERMKLRLLNASHLALASLGWLRGHSMVAEAMRDPALERCIRALMETELSPTLPAdpVDLAAYQDRIVTRFSNRTLQDTVERINTDASINM---LLDPIRDRLADGRPIRRLSLAVAAWIRRLALIEDDA--LALRHPLADALTSLARGGATGEAQ---ILARSDVFG-DLSGNAAFLTAVTRRLRVMTTVRIPARV------
45 UniRef50_Q0AT70 Mannitol dehydrogenase n=3 ... 472 1e-131 1 37.0% 6:470 11:466 -----LPSLVRRPDYVPSQQACGIVHLGVGAFHRAHQAVYTDAAMNAGERNWRILGVSLRTRSV-HDQLIPQDGLYSVSTKSEAAPEVRVIGAIANVL-VAPENPAAVVAALASAATRVVTLTVTEKAY-HQSTGGGLDMNAPAVAADLSH-RGPTTIYGYLAAGLRGRWRESAGGLTLLSCDNMANNGKSLARSLNDFLELYDPALADWTRHNCSFPSSMVDRIVPATTDADRRALSETSGVEDSGAVFTEPFSQWIIEDSFVESRPGWEQHGAQLVNDVAPYETAKLRMLNGAHSALAYLGLARGLSLVSEAIADPQVGRLASRLMREEAATSfpAPGQDLRHYADELEARFSNPALPHRLIQIAMDGSQKIPQRWLDTLSARQETGRDCPAILQALASWILYVRGTSG-----EVDDPMRDQLARTWQSAGHTG-IASALFGESGLFREHWSASETAIEHLNTHIRE----------------
46 UniRef50_C7MVR8 Mannitol-1-phosphate/altron... 472 1e-131 1 40.1% 3:473 6:448 --PRLSPATVEVPH--RPD-TVRILHLGPGAFHRAHQAVFTEDA----GGGWGICGVTQRSP-AVVDQLRPQDCLFTVVERSRTTTSCRVVGTIRDVLFARAE-PERLRAYFTDPKVRIVSLTVTEKGYRPDSG-----------------------VIGQLVAGLEARRATSEAPITVLSCDNLTGNGTVVRSRVLEACARLpdSLASWITDHVRFPGTMVDRIVPATTDADRAEVRSVLGVTDEAAVVGEPFRQWVIEDDFAAGRPAWETVGAQLTDDVAPYEAVKLRVLNATHSLLAYRGALAGYDTIAEAVADPVLAEEAAEFMEHDVLPTLVVpdVDIAAYRRRVLERFANPALRHRTTQVAMDGSQKLPLRLLGTVRDRLAVGEVPIRAVRAVAAWMVYVagRDRDGRPLPLDDPLADRLRAAAGGAGQPHAIVDGLLSVREVFGEDLPDHAALRAALVEAVADIAA-------------
47 UniRef50_Q28N88 Mannitol dehydrogenase-like... 471 1e-131 1 36.1% 4:485 20:498 ---EALPHGIERPTYSRADLTPGIMHIGLGNFHRAHQAWYLHRLMQAGehDWAIIGAGVRAYDAEMRdlAKQDYLTTLIELTPTSTSAEVIGPMIDYL-PIEDGNGALIAAMTDPAIRIVSLTVTEGGYYIDPATHGFDAAHPDMAHDAAHPDSPHTAFGAIIAALRARRDARAPAFTVQSCDNLQGNGAIVRQTVVGLARLGDADLADWIEANASFPNSMVDCIVPATGPAEIA-LARSFGIDDVAPVSHENYRQWVIEDAFCHGRPAWEKVGATLTDDVHSFEAMKIRLLNGGHQVIANVGELLSCETIADCMADPDIAAFFRKVEHDGIVPYVqvPGMTPPAYVELIERRFANSAIRDTTRRVAFDGSSRHTGFILPIVREALAAGGSVDALALVEALWARMCAGTREDGTMIAPNDPFWDDLHATAQAARTRPA---AWLEQTHLYG-DLADHPAFAEAFTGWLSDIWSNGSRATIHRFIA-
48 UniRef50_A6TKR4 Mannitol dehydrogenase, C-t... 470 1e-131 1 24.1% 18:482 12:480 -----------------RNYPEKIVQFGEGNFLRAFADWTIDKMNKEANFNSGVVVIQPLQG-GLIDKLNDQDGLYTLYLNGIkvSEHAVIDCVTRGINTYT-NYDEYLAVAENPELRFMISNTTEAGITYNEQDR---------LEDRPQASFPGKLTALLYHRFKTFNGSKDKGLVFIPCELIEKNGEKLKETVLKLAALWnnDFKVWIDEANTFCNSLVDRIVPGYPKERMEEIRQELGYDDDLVVEGEPFHLWVIEGpwVKEAFPAHKVgvLVVDDMTPYRTRKVRILNGAHTSMVPVAYLYGIDTVRESVEDSVVGQFIKETIFEEIIPTLDLPREELDGFANDVLDRFRNPFIKHQLMSISLNSMSKFETRVLPSILEYerKGELPKKLTFSLAALIAFYKGE-RNGEKIALTDDAAieQYKTLWKAYEGKeiVTTILSNEKIWKMDLNQISGLTDMVTNYLSKIQEHGVKNVLQR----
49 UniRef50_UPI0001AEC29A mannitol dehydrogenase doma... 470 1e-131 1 37.7% 12:473 1:464 -----------KPNYDLEATGCGIVHIGPGAFHRAHQAYYTEKALAYGG-DWRIHGVSMRSAS-LKEALSTQDNLYALCIVDNEPET-HIIGAI-KTLSTLAHDREDIVAALVNKQTKIVTLTVTEKGYCLN-AQGHLDTDHPDIKADLVTPETPVSAVGLIVQALAQRKQAGYADITIISCDNVSDNGKKLQKAVTEFANKTDESLGQWISENIAFPCTMVDSITPATEDSFKANVAAELGLTDNWPIQREAFTQWVVEDNFSGPRPAWDKVGVTFTHDVSFFEKAKLRILNGTHSTLAYIGLLLGKETVFDAMRTPAIKQLIQTMLKEEIVPSLSSDnfDLNAYAQDIVKRYENKHIRHLLSQIAWDGSQKIPFRILDTVRDNLKAKRNIDLLCSAVAAWCLFVNNKARLNET--ITDPLDSMLRATAKSVdqAIELAKKLLSLDTMF-AELSVNNTFKEKVLEKVNQLLD-------------
50 UniRef50_Q3JL86 Mannitol dehydrogenase fami... 468 1e-130 1 40.1% 4:484 19:496 ---RALPPEVSRPRYDRRALRTGIVHLGLGAFHRAHQACYTETLVERGDLRWGIAGVELRRRHT-VERLAAQDHLYSVTERAGDAARTRVVGAVHRTLFA-PQALATLLGLIADPSVSIVSLTVTEKGYYRRPGGGGLDLDDPAIRRDLAQPHAPSTTLGVLAAGIRLR--AAHAPLSVLSCDNMPSNGDTLRALLAQYAEQTDGALARRIRCDVAFPNTMVDRIVPAATPESLDWVQSRIGVRDEAAIVCEPFAQWVFEDRFAGARPRWEDAGALVAADVRPYEKMKLRLLNGSHSAIAYAGQLRGRRTVSDAMADPLIDALARGVMTRELLATLDVpgYDVRAYCASLIERFRNPALAHRTAQIATDGTQKVPLRWLPALAESAAAGVERPFLERALAMWLHYVeaRDESGRPLVLEDPGAQALAARLHGAPGATDAVRAALGL--IASRDAARWPelTARVGAHLETVRTRGTDALLRPLL--
51 UniRef50_B8HDJ5 Mannitol dehydrogenase doma... 467 1e-130 1 37.1% 1:474 4:476 LSIAALAGTGHKVALQRDQLEPGIVHLGLGAFARAHTAVFtdAMLAADDPQWGIIGVTQRS-DAVARQLTPQDGLFTVDERGEGAAPARIVSSIVEAI-SGRDNPDLVVERIAAPATKIVTLTITEKGYRFNPQTRNLDLDDAETIADL-GGRPPRTTVGQITRGLQQRCRTGAGPVTVVSCDNLPGNGELTGTLVRNFAEALpdDLLAWIAANVAFPSTMVDRMVPATTDGDLAAVERELGLRDEAAVVAEPFKQWVIEDNFAADRPRWEESGALFSNDVAAWESAKLRLLNASHSMLAYLGLAVGMETIADAVEVDAFRTACRSMMLEEALPSITLpgMDGEQYCDEVLRRFANPALGHTTAKVGSDGSQKVGLRLLTTVRGTLDAGREPKWAALAVAAWMHHVAG----APATELNDPLAKELQAVLPEDRTADTVVPALLGFRPVVEPYLAGHETFKALLLHWYRIIDNN------------
52 UniRef50_A3HWR4 Tagaturonate reductase n=1 ... 467 1e-130 1 21.0% 17:473 11:466 ----------------RQERPVKILQFGNGNFLRGFTDYMVEEANEKGVFNGNIQVVQVHSP-VADPKMIEQDCLFHVLIRgkQVDEAKLITCIH-GISNPNEDFNTYLKLAENPDLRFIISNTTESGIQFDST---------DINPDELPSSFPGKVAALLYRRFLHFQGDPSKGLIFIPCELIEDNGITLRTCIDQYASLwpKAFTEWLFSACTFCNTLVDRIVPGFPKDSIQEIQERIGFEDKLAVMAEPFHFWAIEGPevKEEFPLDRAgvLFVKDLTPFRTRKVRILNGGHTSMVPYAYLTGIRTVREAVEDPVIGKFMREVIFNEIIPTLDMPKDELEKFANDVLERFANPFIVHELKSIALNSISKFKVRVLPSLLEYYekNLWPEKLTLAFAALLVFYKGEY-KGVETPVNdpSIMAEFKAAWELGSTKETVEKLLSERSYWGEDLREHEGLVEAVSKAVDELLQ-------------
53 UniRef50_A6X6E4 Mannitol dehydrogenase doma... 465 1e-129 1 38.5% 7:486 11:486 ------AAAASWPAYTPENHEVGIVHLGLGNFARAHLLSYTDTVLAQKGGDWRVTGVSLRGT-AVADSLNPQDGRYTLITRGP-VTEAHVIGALDRVLSGPTVGNDA-LDAMTSPGCRIVSLTVTEKGYGIT-SDGRLDREHPAIVADLANPDAPTSVIGLIVAALSRRMTGGLPPFTVLSCDNLSHNGQKLRDAVLAFADQTGGRLlrWIAEKVAFPSTMVDRITPASNAQTAKLAVELTGREDHAAVETEPFSQWVIEDKFCAGRPEWECAGALFVDNVAPYENMKLRMLNGTHSMLAYSGQLSDKSFVRDVMADPDHAVLVRRHL-AAAAATVEGLSIDLDAYAAVLVERFANPAIAHSTAQIAMDGTQKLPQRITTPALEALASGKPYGPFVFALAAWLAYLARKEDDGHPVPLNDPKATELQTGLKDIKTPEEIIRAVAscPDILPSKLT-NGVFGSALRDTLHAIQSEGMPKVIKREAAE
54 UniRef50_A4ADC5 Mannitol dehydrogenase fami... 462 1e-128 1 32.3% 6:470 12:474 -----LPRALQPETYDRT-PKPKVVHLGVGAFHRAHQAWYFDRLNhePEYPWLIEGASLRSKSAG-EQLNPQDGLYVHVARSAAGSDVTVVQSLTQVVNA-FEEPEALTSAIARPDTQLVTLTITEKGYCQNGGNDDLDLHREDVKRDLVSLEHPCTAIGSLLAGLRRRYREKGQPLTILSCDNLSHNGDVTRRAVLAMAEHHEAGLTEWIGDNVSFPNSMVDRIAPAVTAADRDETQKLTGLEDHGLAITEQFSQWVIENNFKGQRPALERVGVTWVDNVDAWELRKLRLLNAAHTALACLGSWLDIRFVHEAISDPRLESLVDQMWRETATTLPDTEDFNLTTYLASLKLRFGNPHLQHALVQIATDSSQKLPQRILAPLAERLAQRDSVTALTTVVAAWLCIQTGQSQRGTDLGFSDPLSETLRRALNEAGDsrTQVDAVFAVYPALGA-LGEDDKWREQLIAAYAT----------------
55 UniRef50_Q1GMX0 Fructuronate reductase n=3 ... 461 1e-128 1 39.5% 1:486 1:468 MTNSLIPCS-----YEQTLLKPRILHIGFGAFARAHPMVYLHHGLVAEGGDWGVVAARLNSGVDALDSLDAVQGRYHIAEADGDTITLREIGLLCGTCHPARDGVDAIPALIASPDMSVILLTITEKGYCTK--DGQLDLTQAAIQAELDG-GLPTTAIGVLVSGLERRRAADLGGITILSCDNQPDNGALTRAAVLGFAEELDLNLAEWIRTHVRFPSSMVDRIVPAMTDDSHTAVASALGRDDPNAVLCEPFRQWVIEDDFANERPPFAEGGAMLVADVQPFEEMKLRLLNGAHTTLAWLGQLLGYQTVADCMADKELRALIRHLMLAEQAATlpLEGIDLAAYADELLKRFENTRLRHRLDQIASDSSQKMPQRLFAPIAINLEAKREWSVSALAVAAWIKGL------GSLPPVPDPRQDELRRAALCN----DPVAAVLSLPSLVPDALRPLAEFQAAISVAFERL-QGGAKATVTTTAKE
56 UniRef50_D1F375 Mannitol dehydrogenase doma... 460 1e-128 1 45.8% 93:485 42:435 --------------------------------------------------------------------------------------------AVSRISWSRRRTPQAVLDIMSHPDTRIVSLTITEKGYCRDAAVSGLDRSHPDIIYDLAHPATPRSALGFITEALRRRRAQGTAPFTVLSCDNLPANGETCKNVIVQFAGCTDTDLAHYIEETVAFPSTMVDRIVPATTDEDRISISRTLKVLDQWPITTEPFSQWVIEDRFPTGRPAWEIAGATFVQDVAAFELMKLRLLNGSHSTLAYLGFLAGHRTVSQTMAAPGFKQLIKALMEIEIAPTLplEGFDLSSYQAALIHRFENHALHHLTSQIAMDGSQKLPQRLLNTIQERLDGGGSIDLLALGVAAWMRYVTGKDEAGTPIDVRDPLSGQLLDQTQGKFAPDEIMDALLSFRQIFTARLAANELFREKLRLALGSLYAVGSAETVRRYAE-
57 UniRef50_B5ZJL8 Mannitol dehydrogenase doma... 460 1e-128 1 36.4% 6:486 22:501 -----LPPAIIVPSYDRGAVRPGIAHLSVGNFHRAHQAVYIDRVlqQDNAGWGILGVGVMDDaaKAESLRAQDGLYTLTECPADadTVRVIGSIVEYLHA-PDDRAAAIRRLADPAIRIVSLTVTEGGYYVDES-GQFQIDHPTIAEDLARD-VPHTVFGLATEALRLRRDSGAGPFTILSCDNLPHNGHVARTAFLSWARARDADLAAWVEAHVTFPCTMVDRITPAVRDPDIARLDAASGIADRAPVFCEDFIQWVVEDTFCAGRPPLEQVGVLFTGDVAPYERVKLRMLNASHSMLGLPGVLMGYRIVSDIMHNPDVIELLERYLGLDAEPLLqpPGMELHEYGALLLRRFRNQAISDQLLRIASDSASKLPVFVRDTAEGTLARGGDAARIAFLLACFAEYLRGRDDNGAAYSVTEPHLGPDDLTLAGDADSARA----LDMSVFAGWGLRDHPDFVALFVRTRAAIRAGGTRATLHTLVTE
58 UniRef50_Q15PN7 Mannitol dehydrogenase ross... 458 1e-127 1 30.5% 6:480 14:480 -----VADTVQKPNYALGAVLPSIVHFGAGNFHRAHQAAYCDALLNQGETRWGITGVSLRSA-KMRDNLAPQNCLYTLAILGEKETRFRVVGAIQN-MAVGPENPQALIDLLASEPTQLVTTTITEKGYYLK--NGVIDLESTDIANDLASLTAPKTTYGYLAAGLIKRASKGDSPITLLCCDNMNAGGERLRDGVHMLLAKHSPETVSWVNENVAFSASMVDRVTPATDELLKTEVAQELGVQDAAPVAAEPFTQWIIEDNFAGDRPPFDKVGALFVDDIAPFERVKLRFLNAGHSMLAALGYLVGDRFIHEALKRPTLAQFTEQALKLNVMPVTSVpgLQAEHYIAQVFARFRNGNLPYAALQVGTDSSQKIQQRWFPSIDDALKQSVDTRYLAFAVAAWVCFIHKALVRG---DLNDPLIDEFTNSSSTGASSD--VLAFLTLAGANKFSFFSDTGFMASVHGYHDYINGMGVEEAI------
59 UniRef50_Q97L67 Altronate oxidoreductase n=... 455 1e-126 1 24.7% 18:482 12:480 -----------------KKYPEKILQFGEGNFLRAFVDWQVDRMNKAADFNAGVVIVQPLE-QGLVDMLNEQDGLYTLYleGKAVKEHSVIDCVTRGLNPYTQ-YEEYLKLAENPEMEIVISNTTEAGIAFDE-------------NDKLGRTCQNSYPGKLTAFLYRRFKtkSKGMLIIPCELIDRNGEKLKATILKFAELWnkEFADWIEEANTFCCTLVDRIVPGYPRDTIEEVHAELGYEDSLVDVGEQFHLWVIEGPeiKDILPFEKAGvqVVKDVTPYRTRKVRILNGAHTALVPVAYLYGLDTVGHSVEDKVIGKYLTELVYDEIIPTLDLPEEELKYFAGAVLERFLNPFVNHYLMSIALNSMPKFETRDLPSLLEYKKrgQLPKKLVFSLAALIEFYKGKRGD-EDIKLADGeiLELYKDLWSKFDGTdiVETVLGYEKNWKMNLNELEGLTDAVTENLIKIDKLGMKEAVKS----
60 UniRef50_C6IZA9 Mannitol dehydrogenase n=6 ... 455 1e-126 1 24.7% 16:481 16:470 ---------------DLPAYPERMIQFGEGNFMRAFTAWQVQQMNKQGRFQGSVVMIKPQSS-PVSEHYAKQDHLYTVLINGIavNEHEINHSVSRLISPYTD-YEQFLALAEQDSLEFITSNTTEAGIAYNP-------------EDRLTDAPQRSFPGKLTALLYRRYQLGKAGFTIIPCELIDRNGEKLREIVLRYAAEWddGFIQWLERENTFCCSLVDRIVPGFPQQKAGQLEQQLGYQDRLMVTAEPYLLWVIEGpwLPERLPLSEAgvIFTEDLRPYREQKVHLLNGPHTAMAALGLLAGLTTVEDVMNDEDLSVFVRELMEQEIVPMLDLPRSGLLSYAEAVRERFMNPFIRHELASISLNSIAKFQTRLLPVLLRYqeRGELPKRITLAFAALLVGYRGD----RLVRKDSPEVLALFDQAWSQ--PAEAIPALLRETKLWGEDLSSVPELADTLEQYVRKLDAFGARATLQ-----
61 UniRef50_Q65F24 Tagaturonate reductase (Alt... 455 1e-126 1 21.2% 17:482 11:477 ----------------KPSRPERILQIGEGNFMRGFIDWQIHRLNEETDFNGSAVVVPPRRGSVTA--FQEQDGLYTLYLEgrEGREVrvITSISRVVSSY-EHYDEFMELADLPDLRFVFSNTTEAGIIY-------------IEEDRLSDRPQKSYPGKLTALLYRRygSREKGLVILPCELLEDNGKILKDIVLRYTNAweQGFIDWLEEANVFCNTLVDRIVPGFPKENAHRLEEAAGYHDSLMVKAEPYHLFVIEGPklRDELPLHEAgvEFVQDVTPYRIRKVRILNGAHTAMTPVAYLAGLETVREAAEDELIGSFVKELIQREVLETIDMPDSELDNYVEEILDRFKNPFIRHKLIDISLNSFAKFKVRNLPVLMEYAErgKLPARTVFALSALIYFYRGqdDGAIPLSDDDEVLAFLKRLWTEETDVSNIAFHVLGFEKVWGQNLNDMPGLTDKTAEYLRDMKQTGMRKALEK----
62 UniRef50_B8H5V1 D-mannonate oxidoreductase ... 454 1e-126 1 37.3% 8:471 23:481 -------PGVAIPTYDRDKLQIGVVHFGPGAFHRAHQAHYFDQLL-AHDPRWGVCAVSLKSPGVR-DALKPQDGLYTLAQLDAE-TTFRIVGSILEVL-VAPEDPPSVFARLAAPTTRLVTLTVTEKGYTL-SANGGLDESHPDIVHDLANPREPRSAVGYLVEGLRRRFAAGLAPYAVVACDNLADNGWRLKAAVVAYAAKLDESLAAWIDREGRFPRTMVDSITPATDDALRARTLAATGLEDAWPIQREAFAQWVVEDVLPADGPDLASVGVIMTDDVRGFERAKLRLLNGVHSTLAYVGILRGHETVFEAVSDPTLAALASDMMAKDIIPTLTPpgLDLQAYADAILGRFRNPEIRHLLAQIAWDGSQKLPFRILGTLTETLEAGRSIERLAVPLAAWMRFVALRAKAGE--AIVDPLQDRLLAllAATGEASADVAAFLALDSVFPASLAGDPRFVSALEKAYADL---------------
63 UniRef50_B7RYR8 Mannitol dehydrogenase ross... 453 1e-126 1 35.4% 6:480 12:474 -----LSVSVELPTYDRDSIEAGIVHLGIGAFQRAHQAVYTDQAMNLSGGNWGIIGVSLRS-DTVARQLLPQDCLYSVLSEGGVEQSLRLVGSVTQVLFAPTQ-LDEVVSAIAAETTAIITLTITEKGYCTGPDGHSLDRSNPVIEADLAAPEAPRSAIGLLALGLRRRQSLGNSPVTVISCDNVAANGQVIACVLKEYTELAFPELSAWLQHNTSCPSSMVDRIVPASTEAQQLRQSQMLGLTDCSAIATERFSQWIIEDNFCSPRPDWRAAGVQYVENIAPYEEIKLRLLNASHSAIAYCGLLAGKEFVDQVVTDRQLGEFVETLMNDDLMPALNApdFDIEGYKSQLLARFRNPCLGHRCEQIAMDGSEKIGHRWLPVLQG----SGENSKLIVALAAWCYLVLYTD-----IAISDPKEAQLLQL--RARRDDSRLRELLACARVTQRTVTSVDSLCRQIEQKIDKLAQGGILALV------
64 UniRef50_C6PA78 Mannitol dehydrogenase doma... 453 1e-126 1 22.6% 16:484 10:482 ---------------DYKKYPEKVVQFGEGNFLRAFVDWMINEMNEKGVFNGSVVVVQPIQ-NGLVNALNEQDGLYTLILQgkAERTYKVVNSISRGINPYSD-YETFLSVAESDSIRFVVSNTTEAGIAFDEND-RFDIT--------PHNSFPAKLTAFMYRRYKHFNGRSDRGLIVIPCELIDKNGLKLKEMILKYADYWnkGFVDWVENDNVFCSTLVDRIVTGYPREDIDKIQEEIGYEDSLVDVGEIFHLWVIEGPkiEEEFPASKIgvKFVDDITPYRDRKVRILNGIHTTMVPVAYLYGIDTVKEAVEDEVVGKFIRDAAYEEIMPTLDLPEDEIKEFVKEVFDRFKNPYVKHYLTSIALNAMSKYETRVLPSLLEYirFGKLPKKLVFSLASYMEFYKGN-RGSETIPLSdpEILELYKNLWKQYDGsyIVTEILAYDKIWKINLNDVEGLNTAVTEYLYSIEKNGIKESLKEVL--
65 UniRef50_UPI0001C35E41 altronate oxidoreductase n=... 453 1e-126 1 23.7% 14:482 16:493 -------------GYLLKDAPERVLQFGEGNFLRAFVDYFIDMMNEKADFNSKVVLCQPIAP-GLADMINEQEGLYTLFLRGFevNDKRVISCVSRCLNPYKD-YDAVLACAKNPDLRFIACNTTEAGITYDPACS---------FTDVPADSYPGKLTQFLYKRFETFGKEPGKGFVILSCELIDNNGKELEKCVLQYAEKwgEEFTSWIKQENIFCSTLVDRIVTGYPRNEAASICEELGYQDNIIDTGEVFGFWVIEGPelKKELPFEKAgvLITDDHKPYKQRKVRILNGAHTSFVLGAYLAGQDIVRDCMEDEVICGFMNKTIYDEIIPTLTLPREELMSFAASVTERFKNPFIDHALLAISLNSTSKWKARVMPSLKGYIAngRLPECITASFAFYIAFYRGTepAGNEYTVKDDRPILQFYYDHRNDDVKTLVHAVCVNEEFWGEDLSAIAGFEDAVAGYVAAIEEKGAYEVMKS----
66 UniRef50_B1K2W5 Mannitol dehydrogenase ross... 453 1e-126 1 36.2% 1:481 18:501 LANATlaPHVAVPAYDRHRLTAGIAHIGVGNFHRAHQARYVDHVLhpGHEKWAICGIGLGSGPASvdALRAQDCLYTLTEFSSDGTtvRVIGAMIEYLHAPAD-PEAVLTRLADPAIRILSLTITEGGYNLDETTGAFRFDTPDVAHDLLG-GPPRTAFGFIVEALRRRRAANVLPFTVMSCDNLRGNGDTARRAVLDFARATDVDLAAWIERYVAFPNSMVDRIAPQVTDAIRLRANRLSGFDDTAPVVAETFSQWVVEDSFSAGRPAFDAAGVELRDDVHAYESMKGRMLNASHMLLAYPAILLGHRFVHDAMADRDLAALLDIFLTRDVGSILTLpgVSARAYARDTLARFRNAALGDQLLRVAHDGASKIPVFHEKTIGALIARHGDMRREALLLACFQHYLKGVDDLGNAFAVSEPQ----FEAADLERVRSGAPLAILDSKPFAPLGLASNAGFVELFRTMQAAVATRRTRDAIR-----
67 UniRef50_Q125C8 Mannitol dehydrogenase-like... 453 1e-126 1 35.9% 5:483 18:469 ----ATPSPVQLPRYRRTDARVGVVHLGLGAFHRAHQAMVFDALLQRGDPRWGVLGVAMRTTE-LADALTAQDGLYAVQVASREALRWQVVGSVLQACVAARE-PAQVVAAMAAPGTRWVTLTVTEKGYG-------------------------PALAALLVQGLAARRAAGLGGLTIASCDNLSDNGRKLQQLCVD-AAQHDAALAQWIDTACAFPNSMVDRIVPAATAQHRSDAAQALGLADACALGTEEFWEWVIERRFVDDADGDAlvGVQVVADVKPFEEAKLRMLNGSHTAIALIGAVLGVPTVADCIARPDIHRFVRSLMTEVVMPHLQRPG--LPAYRDALLARFANPELRHKVHQIATDSSLKIPLRWQATVLAQLAANGSIEPLALAAAVWMRYLLGADEQGQAYAISDPLGQALQATAQRRRDDVatVRALLAVSSIWGEVLPHDVRWTARVEHWLQVIRRQGVAAALAQL---
68 UniRef50_B7AP03 Putative uncharacterized pr... 447 1e-124 1 22.1% 19:484 13:496 ------------------DRPVKVMQFGEGNFLRAFVDYIFDVTNEKTDFNGGVVIVKPIEFGNLDR-FHDQECQYTLQLRGFENGqtRVITSVVDAV-AAIEDYDKYMEYGLCDTLRFIVSNTTEAGIVFDE-------------TDKFDAMPPKTYPGKLTKLLYERYkaKDKGIILIPCELIADNGIELKKCIDKFIDLWndGFKKWIDEACSFCPTLVDRIVPGYPRDEAEELCKEFGYEDQLIDTAETFGLWVIESdqLRKELPFEKAgvVFTKDHHPYKERKVRILNGSHTSFVLASYLAGNDIVKQSMDDPTIRKYMEETLFNEVIPTLSLPEDECKTFANAVIERFQNPFVKHKLLDISLNSVSKWEARCLPSFLGYvkFGKLPKYLTFSIAALMSFYSTtdRNGEKYNIRDDQFVLDFFIENSTKSPKEFAQAYLSNTKFfgKDLSKVDGLVETVAEYITDIRERGMRAVVTDLV--
69 UniRef50_A9KNI5 Mannitol dehydrogenase doma... 446 1e-123 1 20.8% 18:483 12:485 -----------------KDRPVKVLQFGEGNFLRGFVDYMIDVANEKEVFDGSVVVVKPIAF-GNLDMFHEQECQYTLSLRGKekVESRIVTCISDAVDAINE-FEKYESFAKCDTLRFIVSNTTEAGIVYDE-------------TDDFNALPPKTYPGKLTKFMFDRfgDESKGLIIIPCELIENNGPELKKCVLQFAKLWndEFVAWIENACIFCSTLVDRIVTGYPREEAETMCNEFGYKDNLICTGELFALWVIedKDISKELPLDKAgvIFTNNQKPYRERKVRILNGAHTSFVLASFLAGNDFVKESMEDDTVRKFMMSTVFDEIIPTLSLPKAECEEFANAVIERFENPFIKHALLSISLNSVSKWKSRCMPSLKGYVEknTLPKHLCFSLAALMSFYTGSerGEEEYTILDDAFALEFFAANSGKSSKEYANAYLSNEKFFGQDLTKIEGLVDAVASYVEDIRTNGMRKAMENL---
70 UniRef50_A5V7I0 Mannitol dehydrogenase, C-t... 445 1e-123 1 35.0% 1:486 11:484 LSAATVPEGVAPLRYARDRARSGIVHLGLGAFHRAHQAVYTDDAMAAGDAGWGIVGVSLRSPAVR-DALVPQDCLYIVEERGAPGGR-HLVGSINDAL-VAPEAPERVIAALADPAVHVATLTVTEKGYHRDPRTNGLLVDAPDVAHDLAGGGDPRTVFGFLAAALDRRAAQGAGPLTILSCDNLPDNGRLLGGLLDDyaARRGARPGGWTS-----PSSMVDRIVPAITADDLARLP----VEDRALTVCEPFRQWVIEDRFAGPRPRWEAGGAQIVDDVRPFELAKLRLLNGAHSALAYWGLPLGHAHVHEAVCDPDLLAFVRRQLLAEAAPSLPPsaLDPAAYVETILRRFDNPALPHRLAQIAMDGSQKLPQRWLATIVERAATGLASPAHLRSVAAWLAFV--GDASGGGRPADDPLASRLETIWDGQATPADIAAAIVRSSGVFPAAFGADEALVGALGAALAERLSKGPRAMLRDFLGR
71 UniRef50_Q0SCZ3 Fructuronate reductase n=3 ... 442 1e-122 1 34.7% 13:479 4:488 ------------PTLSRRNVptGIVHLGLGNFHRAHQAVYTALAMEREPGPWGILGVASRSS-TVADAMNAQDLLYGVVEISPDGSRVSVPGSHTGTL-VAEQDPESVVRAIADPATKIVTITVTEHGYTVSPETGSLDLDSDAVRRDLREVRTPRTTIGQIARGLALRASTHAAPVTILSCDNLLSNGRQTEKLVREfaPTLRDDLLSWMDSSVTFPNSMVDRIVPSGSDRYNETALAHLGVRDTIAVPAEPFTMWVMEERFAAGRPAWEHGGALFTDDVEPYELMKVRLLNGTHSLIACLGALDGRATIPESVAQPFVEAAARRILCDEYLPTVTVPevDTDDYIRQLFSRWSNTALGHRTSQVGSDGSVKLAQRIPIPALEHLRRGTVPQYLSLTVAAYLCCIagFDPGPHARSMTDPARARLAGMADNAASTTEFVRSVFVDGGLFPSTLASHTEFVSRIADFVDIIVRHGPAVA-------
72 UniRef50_A0QWD8 Putative oxidoreductase Yei... 442 1e-122 1 37.8% 12:482 14:481 -----------PPRPDPNALTVGQVHLGLGAFHRAHQAIYTEDAMRhgETHWAIAAFTQRSGAAATR-LRPQDGLYTVTERGAAASPPRVVGALREVGDGSAD-PTAMVERICDPAVHVVTLTVTEKGYCLDPATGGLDFDHPRIADDL-HSGAPRTVPGVLAHAIARRARSGAGPLTVISCDNLPHNGRLLQQIVHEFSDAAGLSVDD--GATVTYPSTVVDRIVPATTDEDIAALSRSIGVRDQAPVMCEPFRQWVIESRFAGPVPAWSAVGTQLVDDVAPWEQLKLRVLNAAHSTLAYLGLRLGYRSIAEAVHDSVLADICRRLFADDVRPSLDApgLEVGDYGESVLARFANTALPHTTLQVASDGSQKIGPRLLRTVSARAGQGTPARWAALGIAGwlHVVDPVDADGQPTALADPRADELTAMTAGLPVGAA-VRRLVTEPSIVGADVAQRRDFADYVVGVAEDLHRHGADALRAQ----
73 UniRef50_Q9KFI7 Altronate oxidoreductase n=... 442 1e-122 1 22.1% 14:480 16:496 -------------RYKSSQLPERVLQFGEGNFLRGFIDWMIQQMNKQNVFNGRVVAIQPTPHGKVVPKLQEQDSLYTVWLRgeTVDHHEVITSISRGLNPYT-NWQDVLEVAASPDISVVFSNTTEAGLTYLEEGYDK-------------EKAPLSFPGKLAACLWHRYEteGSGLVIIPCELVEQNGKVLKELVCRYAKAWnqEFFTWLERENEFCHTLVDRIVPGFPSDTADECFERLGYEDILLTVAEPYHLFIIEGSevRKLLPFNEAGLHvwNHLEKHRNMKVRVLNGTHTFMFALSYLSGVDTVGEAMADEQLCSFIRKGLFEEIIPCVDAPEQEVTAFAETVLERFENPFLQHRLTDIGLNAVNKFRTRLMPTFNDYVAqgEAPTYLLFSLAALINYYRGVEEDgdSYLIRDDliEAFKVGWQQVNTgaQLCEDLLSKRELWGVDLSMERKVVDKVAESLQIIVEKGMRQAI------
74 UniRef50_C7G7K8 Altronate oxidoreductase n=... 441 1e-122 1 22.0% 19:482 49:520 ------------------ERPVKVLQFGEGNFLRAFVDYMIDIANEQGKFNGDIVLVKPIEFGSLDR-FHDQECQYTVQLRgePKRINRIVTSVADAVDAYGE-YQKYADYAKLDSLRYIVSNTTEAGIVYDD-------------TDRLEMEPPKSYPGKLTKFLYERYkaMDKGLVMLPVELIDDNGIHLKECVEKLAVLWneGFKTWLDEACVFTSTLVDRIVTGYPRDEAEELCKEFGYQDNLIVTGEPFALWVIEskDISKEFPLPDAgvIFTDNQKPYKQRKVRILNGAHTSFVLASYLCGNDIVLESMQDELIFNFMKATIFDEVIPTLTLPKQDLIDFAEAVITRFNNPYVKHALLSISLNSVSKWRARCMPSFLEYIKngKLPTHLTFSLAALMAFYTGTerDGTEYQILDDAAVLEFFAANSSKDAAEYTHAVLSNEHFWGEDLTKLAGVEEAVTGYMEDIRALGMRAAMEK----
75 UniRef50_B7N4U6 Altronate oxidoreductase n=... 441 1e-122 1 23.1% 8:483 2:482 -------KTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFP-PSLSTQDGLYtlNEKGEAVSDARLIRSVNREISVYSE-YDEFLKLAHNPEMRFVFSNTTEAGISYHAGDK---------FDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEwpEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPklATELRLDklNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGqaNGTLPARLTFALAALIAFYRGE-RNGETYPVQDdwLERYQQLWSQHRdtQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDVILEKGMREAVRPL---
76 UniRef50_C6X1L4 Altronate oxidoreductase n=... 440 1e-122 1 21.8% 11:477 7:478 ----------TKPRLNREalPVKILQFGEGNFLRAFVDYAFQALNNELGFNAGVAVVQPLPG-GMVGMLEEQDGIYTVFLNgkKIQEVHLIDNIVQCINPYTD-FQALLDVAREESLEFIISNTTEAGIEFVDT---------DVLSDESPKSFPAKVAAVLYERYTHFKGDRSKGLTIIPCELINYNADTLKTVLLQYHELweDDFAAWINEACTFHNTLVDRIVPGYPKDEEAEFQNKLEYHDKFMVTAEPFFLWVIedEKLKEKLPFDKTnvKIVADMQPYRDRKVRILNGIHTAMVPFSVMYGNETVQETVGDPFTMKYVSEIAFNEILPTLNMDKDELNKFTEEVLDRFRNPFIRHQLSDIALNSISKFKVRVLPTIVEYfkYQKLPVNLVFGFACLIRFYKGS-WNGKILPVKdpEIIAAFDAAWINTSLEGTVSEILENTEFWGEDLNQISGLSAAIVYAIENAEEHGIE---------
77 UniRef50_C7JI68 D-mannonate oxidoreductase ... 440 1e-122 1 30.3% 6:484 11:491 -----VPDTVYTPRYDPALLRPGIVHLGCGNFHRGHQVVATQAAIDAEGRdwGIVSATMRRPD-LATVLQSQDNLYTLLTREPANTVASVMAAITEAVYAG-DDNANLAARIADPATAIVTLTVTASGYYL-SADGRLDPTFEAIQADLTAIT-PRTAPGIIAAGLAQVRQRGGVPPVILCCDNVNSNGATLRQAVIDLAALKGDDlaAWIETNVQFPDTMVDRIVPTATPDDIADACRLLgiEDRAPISAEPWFQWVI-GEFDGPRPRwaHPGTKFVSDVGVFERAKLQMLNGTHMLLAYVGALANLNTVSEAASDDALGRIAARFMRNEQTADVSLDTDELDRYTVDLMQRFRNPGIVHEVTRIGRNGSAKMASRIVQPMRSNIEAGRPVDGAVLLIASWIRWFALHEQDEFDIALTDPRAETLRGLCADARDdkAQAEAFLAMEEVFGAPLPDHGKQVEAIASMLRRLTEESVPELLRTIA--
78 UniRef50_A0M230 Altronate oxidoreductase n=... 440 1e-122 1 24.3% 19:483 23:492 ------------------EYPERVLQFGGGNFLRAFCDWMINELNEKTGFDAGVIVVKPTEG-GNYKELKQQDGLFHVAlrGEMLSEVKLISCVNRVIHSYNE-WDKYLKTALQPEIRFIISNTTEAGIKFSDSDS---------FEDQPPKEFPAKLTLWLLYRFDHFKGAEDKGCIVLPCELIEDNGEELLKTVLQYIKLWddDFQQWIEKHNYFCSTLVDRIVSGFPENRKNEIQQKTGFKDPLLVAGEEYHSWIIKAPEikKELPFEKTnvQFVDELASYRELKVRILNGAHTSLVPVGYLAGLRTVRESMDDDLVLNHVEQVLREEIKPTlkFPESEIDAFIDAVLDRFKNPTLKHYLLAISLNSTSKFQARLLPAFKEYteKGHFPKRTAFSLACMLRFYKGEF-KGESIEVKDdvLSFFNQQWEKKdnTEEFVESILQNKIIFGEDLTQFEGLVRTIAVYLNEIEAEGIRESLRNL---
79 UniRef50_A9QSF6 Altronate oxidoreductase n=... 438 1e-121 1 23.8% 16:485 10:470 ---------------NKENYPVKVIQFGEGNFLRAFIEWQIQQMNNKGLFKGSVAVVQPIEC-GMIDCLEEQNNNYTVVLEgkKIQSDEIISVIDCTINPYKD-FEDYLKLADIESVEFIFSNTTEAGITYD-------------ANDKLGDKPAKTYPAKLTQLLHRRFKNGMSGFQIIPCELIEHNGVNLKKIVLQYAQLWneEFVAWINAENNFYSTLVDRIVPGFPHDNKEEVFARIGYEDNMLVKAEAFLLFVIEGNklEELLPLKKAgvIVTDDMQPYRERKVRLLNGPHTTMTPLALLAGVETVGDVMKDDDFSQFINDEMYDEISPMIALPKDELTMYIEAIKERFNNPFVRHELTSIALNSISKCEYRLLPTIIQNIErgKIPKRITLAFSAWL-YIYGFYGQ-TTVEPQD--TSDVMATLEEMKKSNDYVTAVLGHEAFWGTDLTKYPELVAQVKQNIEDIQKIGTCALVQKINE-
80 UniRef50_Q5WKX0 Altronate oxidoreductase n=... 437 1e-121 1 21.2% 20:485 30:506 -------------------LPERIIQFGEGNFLRGFVDWMIHTLNKKGLFNGSIVAIQPTPHGKVVPKLNAQDGLYTLAQRgtEVDEREIVTSISRGINPYTD-WQKVLEVAENIDVRFMFSNTTEAGLTYL---------QEEYAMERSPLSFPGKVAAYLYHRFQTFQGAKEAGMILFPCELLDNNGQLLKEIVIRLATEwpPSFIDWVDQHNQFCNTLVDRIVTGFPREGIEQFNQELGYEDTLLTTCEPFHLFAIekPEIAAQLPFEKAGLNvwKPVAPFRELKVRILNGAHTMMFAAAYLSGLDTVKEAMEDEELQQFIRTGVYEEILPLLQANEEEKIRFADATFERFSNPFNQHKLLDISLNSIFKWKTRILPSFLEAvkNNALPAALTFSLAALYVFYRPDhdTVYPIRENEKTLRSIQILSDHNGEdqRTIHAFLSNQQLWETDLTAVPQLAETVTFHVQNIGEHGMKAALRSFME-
81 UniRef50_Q097G0 Polyol:NADP oxidoreductase ... 437 1e-121 1 38.0% 65:485 1:417 ----------------------------------------------------------------MAAAMKRQDGLYTVSEMAPDghTSRVVEAMVEYLYAQ-DNPRAVLDRLSQPDIRIVSLTITEGGYLIDER-GQFNLKHPSVVYDLEHPGEPRSAFGYIVEALDRRRKAGIKPFTVMSCDNLRHNGVQARRACVAFAKAKDPELAAWIEREVGFPNAMVDRITPATDNATRQKLRDLTGVDDAAPVICEDFIQWVLEDDFRNGRPEWDAVGVMITPDVSPYEEAKIRLLNATHTMLSYPAYLAGFRKVDDVLHDELFTQYLRDFLNLDAGYWLklPGLEIDAYKAKLLQRFGNRAVGDQVARLCMDGGSKISGFLLPTLHEILKHGRPYHRIAFFLASYERYLKGKDERGEAYPIVEPNARQLLERVIQSSSP----STLLELTEVVGTQLPAHPGFVALYLQLRQKIDTQGVVATLKEIVA-
82 UniRef50_D2PZ27 Mannitol dehydrogenase doma... 437 1e-121 1 39.1% 1:473 1:460 MNRLSLTNLPTKPAVEPGGLSVGIVHLGIGAFHRAHQAVFTERAAQlgDSRWGISGVTQRSAAVR-DQLAPQDGLYSVLTRGGGAASIEVIGSVREVL-AASEDPAAVVQRIADPRVGVVTLTVTEKGYRAR-SGGGLDLTDPEIQADLTG-RPPRTVVGQLAAGLARRSGA---PLTVLSCDNLVANGPYLARLVREYAEAAG--LAGEQFEAAAFPASMVDRIVPATTDADRDEAARLLGVRDEAVVVAEPFIQWVIEDAFAAEQPAWDAAGAVLTADVAPWEQAKLRMLNATHSMLAYLGALRGYETIAEAVRDEDLATAATELMRVDVVPTLTPpgLDLTAYGESVLERFANPALKHRTAQVAMDGSVKLPVRLLGTVQDRLAAGAEPYAAALAVAAWMVYV------SRTAGLDDPQAARLQSAAASAGGPAALVDALLAVDTVFAPNLRENKTFRSLLVDHVTALTR-------------
83 UniRef50_C3Q0M1 Altronate oxidoreductase n=... 435 1e-120 1 22.9% 17:484 11:479 ----------------KTQRPERIIQFGEGNFLRAFVDWIIYNMNEKTDFNSSVVVVQPIE-KGMVDMLNAQDCLYHVNLQGLdvNSLTKIDVISRALNPYSQN-DEFMKLAEQPEMRFVISNTTEAGIAFDPACK---------LDDAPASSYPGKLTQLLYHRYKTFNGDKSKGLIIFPCELIFLNGHKLKETIYQYIELWneDFKQWFEEACGVYATLVDRIVPGFPRKDIAAIKEKLQYDDNLVVQAEIFHLWVIEAPqiAKEFPADKAgvLFVPSEAPYHERKVTLLNGPHTVLSPVAYLSGINIVREACEHEVVGKYIHKVMFDELMETLNLPKEELKKFAEDVLERFNNPFVDHQVTSIMLNSFPKYETRDLPGLKVYLErgELPKGLVLGLAAIITYYkgVRADGAEIVPNdpEIMNLLKELWATGCTQKVAEGVLAAESIWGENLNNIPGLTAAVKADLDSIQEKGMLETVKGIL--
84 UniRef50_C4Z5Q0 Tagaturonate reductase n=1 ... 434 1e-120 1 21.2% 19:484 13:497 ------------------DRPVKVMQFGEGNFLRAFVDYIFDVTNEKTDFNGGVVIVKPIEFGTLER-FHDQECQYTLQLRgePKEITRQITSVVDAV-AAIEDYDKYIEYGTSETLRFIVSNTTEAGIVFDETDND------------PNARPPKTYPGKLTQLLYKRygAADKGLILLPCELIADNGIELKKCIMKFIELweDGFKDWVNNYCSFCPTLVDRIVPGYPREDAAKLCEEWGYEDQLIDRAEVFGLWVVESdqLEKELPFKEAgvVFTNDHHPYKERKVRILNGSHTSFVLASFLAGNDNVENSMKDPVIRKYMEETLYNEVIPTLSLSKEDCEEFAKAVIDRFLNPFVDHRLLSISLNSVSKWEARCLPSFLGYVKknKLPKYLTFSIAALMSFYTSqnRNGEEYNITDDKAVLDFFRDNSGKSAKEFTHAYLSNTKFfgEDLSKVLNLEEVITEYITDIRERGMRAVVNDLA--
85 UniRef50_A6L4U5 Altronate oxidoreductase n=... 433 1e-120 1 22.9% 17:484 11:479 ----------------KTQRPERIIQFGEGNFLRAFVDWIIYNMNEKTDFNSSVVVVQPIE-KGMVDMLNAQDCLYHVNLQGLdvNSLTKIDVISRALNPYSQN-DEFMKLAEQPEMRFVISNTTEAGIAFDPACK---------LDDAPASSYPGKLTQLLYHRYKTFNGDKSKGLIIFPCELIFLNGHKLKETIYQYIDLWneDFKQWFEEACGVYATLVDRIVPGFPRKDIAAIKEKLQYDDNLVVQAEIFHLWVIEAPqvAKEFPADKAgvLFVPSEAPYHERKVTLLNGPHTVLSPVAYLSGINIVREACEHEVVGKYIHKVMFDELMETLNLPKEELKKFAEDVLERFNNPFVDHQVTSIMLNSFPKYETRDLPGLKVYLErgELPKGLVLGLAAIITYYkgVRADGAEIVPNdpEIMNLLKELWATGCTQKVAEGVLAAESIWGENLNNIPGLTAAVKADLDSIQEKGMLETVKGIL--
86 UniRef50_C7H488 Altronate oxidoreductase n=... 433 1e-120 1 24.5% 14:479 16:499 -------------GYILKDAPVKVMQFGEGNFLRAFVDYFYDIANEKAGYNGKVKLVQPIGnpQMADWINEQEGLYTLYLRGSevDAKRVISCVSDCVCPYIDgwDEVLALARSEDLETVVSNTTEAGIAYTQGDSEFDQ--------VPPNSFPAKLTRVLYERYKAFNGAADKGLVILSCELIDNNGKELKKCCNNYAKDWnaEFIDWMNNANTFCSTLVDRIVPGrdPKELAAMEEANGYHDQVLDVGEVFGVWVIEGPalEDKLPFKKAGVNvvPDVTPYKKRKVRILNGAHTGFVLGAYLAGFDIVRDCMHNDTVRGFMNKMLHEEIIPTLPLDKKDLEEFASAVEDRFNNPFVNHELMSISLNSTSKWKARNMPSFLAYieQKQLPKCLTMSLAAYIAFyiCKRPAGNTYKIQDDAWALDFYYAHKDDTDAQLVHAVLTNTQMWDQDLTKIEGLEAAVLADLELIRTQGAEAA-------
87 UniRef50_A7MPR2 Altronate oxidoreductase n=... 432 1e-119 1 23.5% 21:483 15:482 --------------------PERIIQFGEGNFLRAFIDWQVDLLNEHTDLNAGVVVVRPIASDFP-PSLSTQDGLYtlNEKGEAVSESRLIRSVNREISVYAQ-YDEFLKLAHNPDIRFVFSNTTEAGISYHAGDQ---------FDDAPAVSYPAKLTRLLFERFSHFDGAQDKGWVIIPCELIDYNGEALRELVLRYAHEwpAAFTTWLESANSFCSTLVDRIVTGYPRDEVAQLEESLGYHDAFLDTAEHFYLFVIQGPQWLArlRLDKlnVLIVDDIKPYKARKVAILNGAHTALVPVAFLAGLNTVGEAMNDAQICAFVERAIHDEIIPVLDLPRNELESFADAVVSRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQAqgTLPPRLTFALAALIAFYRGE-RNGEGYPLQDdwLARFEQLWTQRGDNteLVDAVLSDCEHWEQDLTAVPGLAAQVTRDLDAILNQGMRHAVAPL---
88 UniRef50_A5FZM9 Mannitol dehydrogenase ross... 432 1e-119 1 34.0% 4:483 17:465 ---ASLPADIARPGYDRDAVRTGILHLGPGAFHRAHQAAFTEDCLAAGETAWGILGASLRSAGTR-DALAPQDFLYTLALREGGREALRVVGAL-RGILAGADAPRAVLAALDDPAIRIVTLTITERGYGCDVARGELDEGDADVAHDLAAPDapRSVPGLLAASLWRRRRAGIAPFTLLSCDNLAGNGRVLHAAVTRMAARRDRGFGDFVAAEVACPSSMVDRIVPATTAEDRARIAARLGCADAAPVVGEPFAEWVIEDRFPTGRPGWERAGARFVTDVAPHERRKLRLLNGAHTMLATIGPGLGCATVAEAVAHERLSPVLARFWAEMAATL--PAETDAAAYCARLRARFGNTALRHELAQIALGSAQKLPQRILLPCLERWRAGRASPVLIAVIAAWLR---GAAAGG------DPLDG-------------------LARREVFAADEWRAPPLRGMIAEECGAMARQGLAARLDAL---
89 UniRef50_A5FC00 Tagaturonate reductase n=2 ... 431 1e-119 1 21.1% 18:486 13:480 -----------------NRLPIKIVQFGEGNFLRAFVEYAIQKLNQKADFNAGIAVVQPID-KGLVNMINAQDGLYTlvKKGEEIQEKELITNIVKAVDPYA-SFQEYLSLAKEEELAFIISNTTEAGIEY-------------IASDLPTMTPPVSFPAKLTVLLNERFkaADKGLTIIPCELINYNADTLKEIVFKYSADwgAEFESWLTNSCSWHNTLVDRIVPGYPKDQIEEYNAQLSYKDDLIVSAETFFLWVIedDKLKAKLPFDKTdvKIISDMQPYRTRKVRILNGAHTAMVPFSLLYGNETVKETVDNEFTGGFINKALFEEINETLNMDKAELAGFSEEILDRFRNPFVKHLLSSIALNSISKFKVRVLPSLTGYVdhGKLPVHLTFAFAALIRFYKGT-WNGQSLPVNDSeiVTFFDGLWKSDDYEKIARLTLQNKNFWDEDLTEISGLTRAITIALEEIDANGIEAGFAKFQER
90 UniRef50_C6DKE8 Altronate oxidoreductase n=... 430 1e-119 1 22.9% 8:483 2:487 -------QTLNRRNFPGRQHPDRVIQFGEGNFLRAFVDWQLDLLNEHTDLDAGIVIVRPIDSDFP-PALDTQDGLYTTIIRgeAVREPRLIRSVNREINVYRQ-FDEYLALAHDPNIRFVFSNTTEAGISY---------HADDSLSDAPPVSFPAKLTRLLYERFCHFDGAADKGWVLLPCELIDYNGVALKELVLRYAAQWkpTFTAWLNDHNTFCSTLVDRIVTGYPRAEVEALQQEMGYQDTFWDTAEHFYLFVIQGPqlAEELRLNKlnVRIVDDIKPYKERKVAILNGAHTALVPVAFLAGLDTVGESMDDALIGKFVEKTIAEEIVPVLDLPHDELTSFAQAVLSRFRNPFIQHQLLSISLNGMTKFRTRILPQLLTYRehGELPARLTFALAALIAFYRGErdTLQTYPLQDdwLERYSTLWAGVKEnaELVNVVLRDADHWEQDLTQVPGLAAQVTEQLQTIVERGMRAAVEGY---
91 UniRef50_A6VU92 Mannitol dehydrogenase doma... 430 1e-119 1 26.9% 1:484 1:476 MTNYLQAsqLSVQDYSKEMIEAGIVHLGVGAFHRAHQAVYIDRLLAhgQQNWGITGVNIRPQDSQaaRFVEQKGEYVLKTMAADGDTkeHIRSIVQQID-GAQEPEKVDSTLADAKTQLVTSTVTEGGYYLDE-NRRLMLEHPAIKADITGARN--TLYAFLYAGLKLRSETSKTKITLLCCDNLRHNGELLETGLMQFLEAkdSALAQWVRQNVSFPCSMVDRITPKPSQKHVDEVRSRFGIDDHMTVMGEDFIQWVVEDKFAGKKPSLDLVGVQFVQDVVPFEEAKIRILNAGHTCVTYQAALKGLTYFDEAMRDEELKQYFTDFILQDSIPAIGDSVVDLPAYFDIIAQRFSNANIGDTVERICTDGYAKFPIFVFPTLEGAYRNGRIPKKTIQGIAGWFVFIQLSNQGKLKTPYHEPNKASLTAFSN----DEAGIQAFATDRFLWGNVPTEYPDFVTELTKA--------IKTTMANYA--
92 UniRef50_UPI00016C06FB altronate oxidoreductase n=... 429 1e-118 1 21.2% 18:483 12:477 -----------------TSYPERILQFGEGNFLRAFADWMVELANEQGVYQGRIVVCQPI-AKGLGDLLNSQNCLYNVLLQGAT-EQLQTIHSISRVINPY-EDYDAFSQLAQNPDLDVIISNTTESGIAYVP---------EDTLADAPPKSFPAKVCAFLYYRYKHFAGDPDKGMLLLPVELIDNNGEKLKQIVIRYAKEweEEFVEWIEKHNEFASTLVDRIVPGYPRLEIDSITEKLGYEDKAVVACEAFNLWVIedSKYKNRLPIHeaNVLWTDDVTPYKKRKVRILNGSHTAVVPLAFLAGFNTVLEFFRDTQFGGFEKDLINDEIIPATDMSQEELRSFADSVLERFNNPHIVHNLIDITLNNSSKFGARCIPTIVDYikFGTCPKHFAFAIAGFIRFYkgYRDNGESYKIKDDIAveLFANIWKNNTIEVVVHETLAN--FWEVDLADD--FEADVLAYLQAMLKDGVAEAMKQF---
93 UniRef50_D1N830 Mannitol dehydrogenase doma... 429 1e-118 1 21.1% 16:485 23:501 ---------------PREEYPVKVMQFGEGNFLRAFIDWMIDKSNEAGRFGGMVQLVQPLP-QGMADFINEQDGLYTLILRgaPAEYKRVVTCVKGCLKTDSE-WDKVVECACLPSLELVFSNTTEAGIEYRPEAYT-------------PGKAQQTYPAKLASLLYERFKAGRKGLVIVPCELIDRNGAKLRECILHYAADwgGGFVKYVENECAFLNTLVDRIVAGYPRAEAAAYCEKLGYEDKLLDCGELFHLFVIedEKFRKVIPFAEAGlvWTSNQTPYRSRKVRFLNGGHTSSVLAAYLAGFDFVDKMTADPLFGRYLRTALFDEVFPTVQLPDGEKKAFAESIIDRFLNPFANHQLISISLNSISKWQVRVLPSLLDYVekGRLPKVLTFSFAALLAFYRGtkRAAGSYPISDDDanAAYAELDRSGDYRSFIETIASKTDFWGRDLNQVPGFTDAAAAYLKSIEDDGVAAAVRKLLE-
94 UniRef50_D1BAE2 Mannitol-1-phosphate/altron... 428 1e-118 1 40.7% 8:474 29:544 -------SGVTGPAVDPSAVTVGIVHLGIGAFHRAHQAVFtdAAAAAGETGWGILGVTQRST-AVVDQLVPQDGLYGVRTVGKDSSSLRLVGSVRGVAFPG-EETQRVLDAIAAPTTHVVTLTVTEKGYRA-GADGRLDLGDRDVLADLEaaVPARSAIGLLVRGLAARARAGGEPLTVLTCDNLLDNGHVLEGLvlDAAAGLpeRLRAWLRASVTFPCTMVDRIVPATTEGDRAAAEEATGVRDEGLVVAEPFMQWVIEDRFAGPRPAWELAGATLTDDVAPFERAKLRMLNGTHSLLAYLGSIAGHRLIADAVADPELLAAARSLLVDDVTPTLVApgLDLATYAESLLERFANPALGHTTIQVAMDGSKKLPIRFLATAADRLADGAVPDAVAHGVAGWVVFVagRTVAGEPLRLDDPIADELRAAAAEVAGPDelVRRMLAVEQVFPAEVRDHAGFRDAVVAHTERLLAG------------
95 UniRef50_A4QGN7 Putative uncharacterized pr... 428 1e-118 1 35.6% 17:471 13:449 ----------------PDAPPVRLVHLGLGAFHRAHQVWYTQKA----DPTWGYASFTGRSA-RMSDALTPQDGLYTLVTRSGEGDSPELISSLVEAQPAA--NVERLVELMADPQVAVVTLTITEAGYHL-AADGSLDEAHEDVASDLEALaeLKTAAGKLVKGLAARKTAEAGGIAIMSCDNIADNGALTSGAVLGLAAKVSPELAAWVKDNVTFPSTSIDRITPATEDSLIADVEAQTGFHDNAPVVTEPFASWIIEGEFPAGRPNWENAGVEFVSDIEQFERRKLWLLNGSHSLMAYFGQLRGHATVADAINDSVVRSHVEALW-DEAANHLTAEGLNVPGYRQSLIERFENPRIVHNLAQIAIDGATKQRMRAVPILKAELAAGRPGNGAALSIAAWIAYVLGTE------EVRDTRSAEI-------NEAKLLDDAILGLITVLDEDLATNDAIVTHIKKVVSEL---------------
96 UniRef50_D1PT81 Altronate oxidoreductase n=... 424 1e-117 1 22.0% 16:484 13:493 ---------------PKGNMPERIIQFGEGNFLRAFVDWIIYNMNQKTDFNSSVVVVQPIER-GMVDWLNGQDGLYHVNLQGKevNTLTRVDVISRALNPYTQN-QAFMALAEQPEMRFIISNTTEAGIAFDDNCK---------LSDAPASSYPGKLVQLLFHRYKFFGGCPSKGMIIMPCELIFLNGHHLKNCIFKYIELWKDdfKEWFTKYCYVCATLVDRIVPGFPRDTIKEIQEKICYKDNLVVKAENFHLWVIEkdELKAEFPAHKAgvLITDNEKPYHERKVTLLNGPHTVLSPVTYLSGVDIVRDACEHPVLGKYIHKVQFDELMQTLDLPMDELQQFAADVLERFENPFVDHQVTSIMLNSFPKYETRDLPGVKIYLQrgELPKGLVFGLAAIITYYkgKQADGAPISPNDdiMDRLTELWA-TGDTQKIAEGVLAFDYIWKEDLNqvPGLTALVKTYLDLIQDKGMLEAVKTIL--
97 UniRef50_C5EW18 Altronate oxidoreductase n=... 423 1e-117 1 21.4% 18:479 8:444 -----------------NNVKETVIQFGEGGFLRGFVDYFFHKLQEKGLYDGKIVVVQPIE-KGMCQMLADQNCEYNLFLRGIdvNEHTHVTSISRALNPYTQ-YEEYIALAESPDLRVLVSNTTEAGIEYLGTEKLSDM-------------PPKSYPAKLCQFLYKRYKAGLKGLILLPCELIDDNGDNLKKCVLQYADLWedGFKNWLETDNDFCSTLVDRIVTGYPRDEVEELTKKIGYEDKLIDTAEIFHLWVI-GGHHEDELPFQKAgvVWTDDVHPYKKRKVRILNGGHTSMVLGAYLYGLETVGECMKDEKVSSFLKKCIFEEIIPTIG-DTEDNRKFGAAVLERFSNPFIKHLLLSIALNSVSKFQVRVLPTILEYKEkgKYPAALTFSMAALISFYR-TDKANDGEEI-------------LAFMKTASVEDIMKREDYWHEDLSEM---IPMVQEYYDLIQDKGMAEA-------
98 UniRef50_C0CKL6 Putative uncharacterized pr... 423 1e-117 1 22.0% 18:485 20:495 -----------------RDVPEKILQFGEGNFLRGFVEDFVDQLNQKTDFCGKIVMVQPI-MQGSSDKINAQDGLYTLYLRgrKINERRIIQSVQRCIDPYRE-WESFLECAKNEELEFIVTNTTEQGIRYDPACE---------FGDCPQSSFPGKLTRFLYERFLVTAGDLEKGFQILSCELIENNGTELKKCVLAYAKQWgqKFIRWIEEANTFCNTLVDRIVTGYPMGESERLNRENGYEDKLIDTAEVFGFWVIEGPelNEKLKLDEVniHICRDHIPYKKRKVRILNGAHTSMVMAAYLMGYEIVRDCMEDGLICRYVEEFLSTEVIPTIDLPREDLQNFSIAVIERFKNPFIDHRLLAISLNSVSKWRTRVLPTVLEFQKRFGYVPLIafSFAALLQFYRgaYREGTPYYVCDSEDILGFFSQNSSKSMEDYAYQIAKSSWLWGRDLSLIPGFLPLVVKSLEKICDRGMRGAMDWILE-
99 UniRef50_C2H7R3 Tagaturonate reductase n=11... 423 1e-116 1 21.5% 17:482 11:465 ----------------KNEAPVKVLQFGEGNFMRGFVDWQIQQLNNQQLFKGNVAIIQPLE-QGLGNMMNQQDNLYTVIlnGEIVDTSEIITIVEQMINPYHE-WDAYLSLAENDDLAYIVSNTTEAGIQF-------------VETDERTDTPPQSFPSKLTAFLYRRFELNKAGFTIIPCELIDRNGERLKEIILRYAEKWdpAFIEWLEKENVFCCSLVDRIVPGYPREDADVFNQRHNYEDQLMVKAEPFMLWVIEGpeLENQLRFKQAgvIITDDMTPYRERKVHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFDLELIPMLSLPKDELAIYADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYieKNQVPPLISVSLAALLLMYR-----GDQVKPYDDEKT-ISEFVDAWSDNETAILRLLQNAALWGEDLSQLPNVADTVQEMATKIDQKGVRAVLQE----
100 UniRef50_B7GPP4 Mannitol dehydrogenase, C-t... 422 1e-116 1 31.9% 5:471 8:458 ----TSLPRLNRAEHGRAAAPVRIIHLGIGNFTRAHQAWYTEHA--PDTAQWGIAGFTGRSR-RMVDKLAPQDNVYTLITSAPEGDSFEVISSISSMHEGG--DMAALHKYFADPNVSIVTSTVTEAGYKRN-AHGDLDVNDTDVSEDLanVSELATVPARIVAGLEARRAANAGAITILPCDNLAGNGAAFRRVVEQAIEAVDPTLLEWTRDNVAWATSMVDRITPATTDAELQTVAQDEGWYDVAPVRTEPFLEWVIRGDFPKGRPAWDKAGAVITDDVEPYEQRKLWMLNGSHSTLAYVGPLFGHESVAEAIADPQLRAWVNEWWDLAGSYL----SVSSDDYRAKLLERFSNPRIHHHLFQIATDGSQKLPVRIVPVAKHALADGRDITAPARAVAAWIVFLRRF----GNTEAKDVNLDEVRKLAVNDDVTPAV--------SYLDKDLGANATFTNKVSELVNEL---------------
101 UniRef50_A7Z3M8 UxaB n=2 Tax=Bacillus RepID... 420 1e-116 1 21.6% 19:482 14:472 ------------------QYPEKVLQFGEGNFLRAFADWQIDQLNQLTDFNGSVVAVQPRGSEK-IKRLNEQDGLFTLFLQgkPAEEHTIVKSISRGIDLFSD-YDSFKRLAAQEELRFIISNTTEAGITFE-------------KGDRLEDRPQKTFPGKLAAFLYFRYKaaEKGCIMLPCELVEENGRKLKAAVLQYAGLWepDFTQWIHDANIFCNTLVDRIVPGFPVDTAEELTDFLGYEDRLLVVGEHYYLWVIEGpqLQNELPFAEAgaLITSDLTSYRTKKVRILNGAHTALAPVALLYGLQTVREAAEHEVTGRFIEELINEEILPVLQMEGV--TQYAADVLQRFKNPYIQHYLQSITLNAAAKFKTRNLPTLKAYIEqgRLPEKLVFSFSAMIyyWNGPNKPADGEGV---LNRFQMARSRCKDDMFQAASSILGEERLWGKNLNHLPGLTERTAFFLSVIHKRGMKHALHE----
102 UniRef50_A0JS82 Mannitol dehydrogenase n=3 ... 419 1e-115 1 35.5% 11:466 5:454 ----------QAPVLNRALMpvRIVHLGLGAFHRSHEAWYTQHAGD--GAEWGIAAFTGRRPDA-ARALAAQDGLFTLIERSGDGDSFEVIGSITEAVDGA--DLGRLRELVSAPATAMVTLTITEAAYGLAP-DGSFHAGAPEIAEDLAMLAhpRTPLGRLVSALAGRRDAGSGPIAVVSCDNLSGNGDVARRAVTGMAEAWDSELALWIGENVSFVSTSVDRITPRTTDADIAEVEQACGYRDSTPVVAEPFRDWVISGDFPKGRPRWEDAGAVVVDDIEPYENRKLWLLNGAHSLLAYSGQLRGHTTVAQALEDPACRDAVEAFW-DEAAAHLRGDDLHIPEYRDALRGRFGNGRIAHHLSQIAADGTTKLRMRALPVLAAERSEGRSGAGSALMLAAWIDFVAVHK------ELQDPMSDAI--GTANGARGPERVASLLNLIS---PQLGGDPQIVALVAG--------------------
103 UniRef50_A9VD39 Predicted protein n=1 Tax=M... 419 1e-115 1 28.8% 6:473 1:463 -----MAVELQRIKYARDQVQAGIVHLGVGAFHRAHQAVYWDTLLPE-DPRWGVCGINLRAADRafEALQAQGGLYTLKTLAFDgtEYRQVGAIVELIDASRD-YGAAVARAADDHIQIISMTVTESGYYLDEAD-VLRTQAPDVAQGLA-QQPTSCVYTYLHGAMRARMAGNGRPITLMSCDNLRENGHKLRTGFLQYLKAadEATRAWVEAHVSFPCSMVDRITPRLDPAHARDVRERFGIEDQVTIMAEPYIRWVIEDNFAGARPPLDRAGAIITRDVQAHEEAKIRVLNGGHTALAYLAALRGHRTFDRAMTDPELADFFMAYETEEVIPGLGESPIDLAAYRDEICARFSNASIGDTVARICSDGASKMPIFIRPTAEATARRGLVPHHAIRIMASWYVFMRAVQRGGedFAYVEPSWDTLVPLLAAGQET-----TFATHELLWG-DLPqcPTFVECLVAEIAKQEQ-------------
104 UniRef50_D1BXN9 Mannitol dehydrogenase doma... 415 1e-114 1 34.1% 6:462 14:482 -----LPDGVLAPPVVPTGV--GIVHLGWGAFHRAHQALYTQEAMAagDLSWGILG-DVERTPQLVPALREQDGRYTVLSVGLEgeQATVVASVLDVAYPGDETP-RLLAAMAAPTTHLITLTVTEKGYCRT-GDGHLDLGQAQPDVDAFVAepAATAMGLLVRGLAARFLGEGTPVTVLSCDNMAHNGKVLKRIVDEFIAAAGPafSAWLAASTTWPSSMVDRITPAVTPATLDRVEEILGARDEAAISGEPFRQWVIEDSFAAPRPQWELVGADLTDDVAPWEEAKLRMLNGTHSLIAYSGRLFGYATMAEAVVAPEIADHARAYMFEDALPSVTPpgADLPAYGEGLLERFANPATGHSTRQVSTDGTQKIPFRWGGALQFALSNGRVPQGIAFGLAAWSEFVRRAVRDG--VDLGDPAGTelTAVVTEHGNDVEGvrGLLALPGVLPGGAGNHPELAD------------------------
105 UniRef50_B9Y6P1 Putative uncharacterized pr... 413 1e-113 1 20.3% 9:482 4:474 --------SLNRQNHPRPQRPVRILQFGEGNFLRAFVDDFISQLNEKTDFNGSVCVVQPRPH-GRVKSLMEQDGLYTLLLEGKKerEMRIIDVIEQGIDPYTDYP-ALLQRAADPQCRVIISNTTEAGITY---------TDELVTLDVCPQSFPGKVLAVLKHRFQTFNGTLESGMDLVCCELIERNGDTLKEIVCRKAREQGeaFLDWIENANRFYNTLVDRIVPGYPKAQAAALEDQLGYHDAYLVKGEIYHSWVIqdPVLHSVLPLDQLniIFTDDLAPYRDRKVAILNGAHTAMVPLGLLGGLETVKETVEDPQIRRFLEAFLKEEVWPSLNFSESELVAFTHDVFERFENPDIRHELMSISLNSIAKFNTRDLPAMRHYYdhKALAPHACFSLAALIVLLGQRKSDGTPLISESPEVLACWQDWDENQ-PQATVDALIQL-PLWEGQLASMDNIAERLVQIIHSIATLGLRDALKK----
106 UniRef50_UPI00019136C4 D-mannonate oxidoreductase ... 412 1e-113 1 61.3% 149:484 1:337 ----------------------------------------------------------------------------------------------------------------------------------------------------LAHPQQPKSAIGYIVEALNMRREQGLKAFTVLSCDNVRENGHVAKAAVLGLAKARDAALAAWIADNVTFPCTMVDRIVPAATEETLQLVADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDTVGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYDTIADTMTNPAYRRAALALMLDEQAPTLSMpgTDLEGYANLLIARFTNPSLKHRTWQIAMDGSQKLPQRLLDPVRLHLQQGDDYRRLTLGVAGWMRYVGGVDEQGKTIDVVDPLLAQYQAIHQQYQTPEERVRGLLAIESIFGNDLPKNHEFVQAVTDAYQQLLQNGAKATVEALA--
107 UniRef50_C6D022 Mannitol dehydrogenase doma... 411 1e-113 1 19.9% 2:473 11:500 -LNYASLREGEASSYNrkSYPVKVLQIGEGNFLRGFVDWMIHRCNEQGLFNGSIAVSQPRpgAAKLKELKEQDGLYYQWIRgeLIDRRELISVFSDFIDPY-QEWERFLAQAANPGLELVVSNTTEAG---------LVYQASEWAPDQPILSYPGKLTLLLYRRFEHFGGDSGKGLLLLPCELVERNGDKLRDIVLQHASDwpEAFAVWIREHNRFLNSLVDRIVTGFPAEEANERYTEWGITDRLLNAAEPYHIWAIEGEelDERLPFVKAgvVWTNDLQSYQLRKVRILNGAHTWMAAYGLLNGLNEVREVVEHPMYGAHLREVVFNEIVPSVPLPEAEMKIYAEQVIERFANPYVRHKLTDIAMNSLSKFKVRLLPTLMAYYERSGdpPYIVTAFASLLKLYrgSRLDGSQLLIRDDAaaELASLWNKADNGeeLLEDILGRDSWWGIDLNGIAGLSDRLTAEFAHLEE-------------
108 UniRef50_A8RNV1 Putative uncharacterized pr... 410 1e-113 1 20.1% 19:486 2:444 ------------------ARKETVIQFGEGGFLRGFADYFFQKMQDKGLFDGSVVIVQPIE-KGMCSVLEQQGCEYNLFLRGIdvDEHTHIDIISRCVNPY-DDFEAYMKLAENPDFRFIVSNTTEAGIEYVDSNQ-------------FTDAPARSFPGKLTQLLYKRYRLGLKGFIILSCELIDHNGEELEKCCLRYAKQWeeEFETWLVRENDFCSTLVDRIVTGFPRDEHEELCRRIGEQDNMMDTAEIFHLWVIQGS-HEDELPLQKAgvVWTDNVDPYKKRKVRILNGAHTSMVLGAHLYGLKTVGECLKDEKVSALLRKCIFREIIPAIG-DTEDNRKFGEAVLERFSNPFIRHMLLSIALNSVSKFRARVLPTILEYRdfGSCPQGLTFSLAALMAFYR-TDDANDSQEIMDFMKT-------------APVEDILKREDYWGQDLS---PLLADVKKWYELIETEGMDKAYDAVLSE
109 UniRef50_C1FJR8 Predicted protein n=4 Tax=M... 410 1e-113 1 30.7% 11:485 68:567 ----------RPPAVDRAACKSGMMHIGVGGFHRSHQQAFMNELLDVNFdnWCTTGVGVMPNDSAMRdlRDNDWTYPIVArgTDAseVEEVYALRDMILA-FEDPIACIEAMANPDVKIVSLTITEFGYrlNSSDFKFIERALNGEMDCETPYpkPSTFGIICAAAAARFERGQRPFTLMSCDNLPHNGDVCKGRMTSAAEELvdEFVVWLQNEVRYPSTMVDRITPATSWDDIATMPDKYGFEDKWPVMCEPYKHWVIEDDFVDgrPPWETVGATLTKDVVSHELMKVRLLNVTHSAMCYVGILAGLTHVHEACLHSKIRSYLELVMLEEIAPTlaNPEMdiPSYARSVLERFENVAVKDQLDRIAMDGSEKFRVQGSGVIREGIALGLPMDAFALYVAAWAHFVKREVEAG--VEVKDMGAQGVTAPFRPGGTG---LPAFLDMVDIFG-DLAMDLTWRQNVTRMYDTINEHGMEFALDVVLG-
110 UniRef50_UPI000178868B Mannitol dehydrogenase doma... 410 1e-113 1 21.4% 19:472 32:500 ------------------DFPVKVLQIGEGNFLRGFFDWMIYECNRQGLFQGSVAVSQPRPGGrkLEQLRDQEGIYGLLTRgrKVEEEQWIPVFSKIVDPYAE-WENFLRIAELDSLDIIVSNTTEAG---------LDYQRSEWNPDEPVLSYPGKLTMLLYRRYKHYEGSPDKGLMILPCELLERNGDILRSIVLRHAQDWgpAFQSWVAEHNLFLNSLVDRIVTGYP-EEAERYFDKWGHQDRLLNTAEPYYFWAIedPSLESRLPLRSAgvSWVSDLTPYQVRKVRILNGTHTLMASIGLLHGLNEVKEMTESPEWGDLIRNAMLEEIVPGVPLPPEEVAAYAETVWERFGNPFIRHRLQDIAMNSMSKFRVRVLPSLKEYIrhNELPSTITLGLASLIRLyyGTRLDGEELPLRddNLMTLQQAWQKVDGGeqLVASILGNQRIWGEDLNRIPALHETVSSYIEEME--------------
111 UniRef50_A3PQL9 Mannitol dehydrogenase, C-t... 409 1e-112 1 35.5% 22:480 4:452 ---------------------PTILHLSPGAFHRAHQAVYAEALIRAGHPEAGIRDVCLFPPLIGAAH-AAQGGTYHVLLRDQTREDLRRITAIREVLDRPHPDM------LCDPALRLVTMTLTEKGYCHVPGTERLDP--AAVAQDLADPQHPRTALGWLALALVRRRAAGLPGITLASCDNIPVNGRLLEAVLTAYVAEAFPDLLDWMAANVTFPVSMVDRIVPRVDAAAAESLAALAGAPDALGVVAEPFGQWVIEDRFALPIPPLDKVGVQIVADVAPFERMKHRILNGAQTAIAHLGALSGFATSFDAASDPVMGVWLERFCAAQARTLACPPGEDLAAYCRATMERLRNPHIRHPLTQIGTDSSFKLGQRIVEAAEHHLD-GPEARLYALTIAAWMRYNTGRDAAGRPIPVEDPLAPVFRDilAAGGDPSALVAGYLQLD-LFEGPLRQNEPFRRRLVALCTALETRTPRDII------
112 UniRef50_C6WS61 Mannitol dehydrogenase doma... 407 1e-112 1 37.5% 6:477 15:474 -----LPAH-ARPAADPRELPTRALHLGLGAFHRAHQAVYTEHA-----GGWGIAAIAPRSRDV-VAALRAQDCLYSVVERSPERPSARVVGSITEALHA-TDDADRVRALLTAPETSVITLTVTEKAHHRRADGRGLDLAAPEIAADLTSP-APSTVVGRLAAGLALRHRTTGAPVNVVSCDNIADNGAVLAGLVRDYAEAAnaAFLAWLDTAVAFPSTVVDRIVPATTEDDRATAARALGLRDEATVAGEPYRQWVLQDAFTADRPAWERDGALLVPDVRPYQVTKLRLLNGSHSALAHLGAAAGCTTIREVLHTAWGERFVRAF-CAEVAPTLPEGGPDPAGYADDLVTRFRNPAVRHLLRQIGSDSSLKVPERWLDPLRALDRA----PLLELALAGWVASTRPGDDDLPVHGTTDPLSDELAACWHDRPAHPELVARLLRLVG--APDLAERTDLTTAVAQRLPALRAGRVE---------
113 UniRef50_A4XMX2 Mannitol dehydrogenase, C-t... 404 1e-111 1 25.4% 9:485 19:539 --------QIEMPQFDIEDfnPTWIHFGAGNIFRGYIAALEQDLLERGEVQTGIIAAELFDYEIIDRIYKPYDNLSLVVTADAKGnqKRIIASITEALKCDpdDWARLCEIFKSASLQMVTFTITEKGYNIVDLNGEYL---PQVKEDinGPEKPKSSMGKVTSLLYVRYKNGKHPVAVVSLDNCSKNGERLYNSIIQIAKEweEGFVEYLSnsVSFPWSMIDKIVPRPSDSIRELLEKD-GLeiAPFVNTEKSQYLVIEDSFPNGRPPLEKAGVYFTntVENSERMKvtCLNPLHTALAIFGCLLGYKTIYEEVKDGCLKKLIEKIGYEEGLPVVVDPkiDPKEYLKEVieRFPNPYIPDAPQRIATDTSQKMPIRFGETIKAYSESpkSLRFIPLVIAGWLRYLMCVDDSGKPFEPsdPLLEELKKHMNgaENLEEKLKPILSNEMLFRVNLFEI-GLASKVIYYFEEMTegAVRRTLEKYLE-
114 UniRef50_C6XUU7 Mannitol dehydrogenase doma... 404 1e-111 1 28.6% 1:486 4:493 LNNNLsaKEIKVPA-ALKSSRSQILHIGVGGFHRSHQVYAIQQLIDSnfSKWAITGVCMMPEdqLVENLRKQNQRYCLKMSTPSgeDIRVMNAIASILHSASDAV-KIVNRIASAETKVISFTITEGGYNIDFDKSRFLIENPAVQADLINPDQPGTVFGFLAKGLALRKLRNNGPITLMSCDNIQENGHILKLALLSFISVYDESLLPWIADNVRFPNSMVDRITPVATEKDKADFERQYGLRDNCLVVSEDYFQWVLEDNKYGDFPPLEQVGVEIVAEVKPYEAMKLSILNGGHTLVGLLGDALGYNRIHNAVVDEAISRIYDMYVQQEVIPTLAvdGVSFYNYYEKVKLRFSNAMINDSTDRIISGSSDKVPKFVLPVLQEQLKNSSPKKDItlIIIAWWVYLEKEFNKNQMADVKDQKVTEWLPMFETAKGNGDW---FISYKPVFGA-LAEHVELVNLYKAYMKVVQEGELGSLIDKILEK
115 UniRef50_D2QJY5 Mannitol dehydrogenase doma... 401 1e-110 1 23.0% 8:485 13:513 -------AKLTRSTHPVPVYPEKILQFGTGVLLRGLPDYLIQKANSEGKFEGSIVVVKSTDSQT--NEFSDQDNLYTVAVRgqEVVENTIVSAISRVLAAQTQ-WNDVLVLARNPKLQIIISNTTEIGLNYVEES--------------IFQHPPQSFPAKLTAFLYERfgSKAKGLVVIPTELVTDNGLKLREAVEKLAqeLGKLFTKWLKFHVRFCNSLVDRIVTRPTEEDKLALENEAGYEDDLLTFTEPYHLWAIedDRVKQTLSFatPQIIIDEDINFYKERKLRVLNGTHTLTMPLGYLLGLETVADEMRHPAMSKFVEQLMLNEIVPTVPdpGMDKAafAHDVLDRFRNPHLDHLLLNISLQQTAKMQARNVATlrYYEQFNTAPKLMAFGFAAYLLFMKATREENGqyPVRDDKAGYFYGDWkdAATVDAFVKSVLSDTTLWQADLTALPGFSEAVAENLNALLTEGVEKSLEKVIA-
116 UniRef50_C3QT19 Mannitol dehydrogenase n=4 ... 399 1e-109 1 29.1% 14:481 5:440 -------------NYNRAEIKAGIVHFGVGNFHRAHLEAYTNLLLEDPSQrwGVFGAMIMPTDGVlnALKKDDGIYQLTTCSPSGedSMLIGSLVE-LAWGEIDSEPIIAKIASEEIKIISLTITEGGYKVDFNQS-------------------RSVFWYVAEGLKRRMEKDL-PITILSCDNMQMNGNVAKCAFMSYFEEKYPEVAAWAKKKVTFPNSMVDRITPVTKPGKGTD------------VCCEDFIQWVIEDNFIAGRPAWEKVGVTFTHDVTPYEIMKLSLLNASHTLLSYPAYMEGFRKVDAVMADERYRAMIKLFMNRDVTPYVPVpgVDLEAYKDQLIERFSNKAISDQVSRLCGDGIAKFAVYVVPILKQMLQDGKDISIEAFLIAVYCKYLIGAreSGENIAISEPHITPADRKLISGGSPAE----FLKISPFVSLGLDKYPVFMEKYEQFYAMQVAEGLKVLLQ-----
117 UniRef50_D2QL58 Mannitol dehydrogenase doma... 399 1e-109 1 21.2% 1:481 9:508 LATHACPTAISLPPAHVQRLPERVLQFGTGVLLRGLPDYLIDRANRQGIFNGRIVVVKSTDGGDMT-AFARQDNLYTLCIRGIevEENVICSAISRVLSA-KQQWDEILHLAASPDLQIVISNTTEVGIQLT--------------QDSIQLSPPDSFPGKLLAVLYARYKalNKGLVIVPTELIPDNGTALAAILRELanELGSEFIHWLETANTCCNSLVDRIVPGHPDatRKALTEELGYEDDLLTISEVYRLWAIDVPAGSDelSFHQAdvFIQPDIDLFRELKLRLLNGTHTLSCGLAFLGGFTTVREGMEDEQLSAFVSRVMLTDLIPGIPYPIDEAVafGMQVLDRFRNPFIEHRWLGITMQYSAKMKMRIIPVLLHHYeqPATPQYIALGFAAYLLFMRGveRAGEAYPINDSQADYFAGLWAGL-SPAALVDTTLKNTDLWGTDLSRLPGFAEAVSHNLLQLLEQGATATLA-----
118 UniRef50_C6W4F6 Mannitol dehydrogenase doma... 396 1e-109 1 21.4% 19:486 27:503 ------------------QLPEKVLQFGTGAFLRGLADYFIDKANRQGVFNGRIVVVKSTD-QGDTKAFERQDNLYTICSRgeAKEENIISSAISRVLSAKTQ-WSLVLDLAKNPAVGIVISNTTETGIQL--------------VQDDIYQWPPVSFPGKLLAFLYARygSADSGVVIIPTELIAENGKKLESIILELAHrlEVAFIDWIEQCNFFCNSLVDRIVPGKPDETrkELEEELGYRDELLITTEHYHLWAIedEQIRQKIGFydEGLIIEPDIEQYRELKLRLLNGAHTLGGGLAHLCGFKTVVEAMSDPFFSAFITHLMESEIATAIPYdpAVALAFSRQVADRFRNPHILHKWFNINQNYSAKILSRVIPTYLNYEARNglPEYMTFGLAVFIHYMKVVKKEGdpYLIQDPKAPFFYQKWQMA-SLPDMVQAILKDASIWGRDLNKVESVHSSIVKYLQSIAQNGVAETLKTLLER
119 UniRef50_UPI0001C347DF Mannitol dehydrogenase doma... 395 1e-108 1 31.1% 21:406 5:389 --------------------KSVWMHIGAGSFHRAHQAWYLHRLCQQGDDSWSIALGNIrdANALLDNLTKQNGEYTLETVSPEGERheKITSVRKVLHWD-ENLSQLVEQGCDKATRVIAFTVTEAGYYLTPQ-HELDAEQPDIKADLTG--KMSTIYGALTQILRARLAAHGEPVTLLNCDNLRHNGERFRHGFLSFLQLKGeeLYQWVKENTRSPNTMVDRITPRPTPDVAERVKQHTGWDDKAPVMGEAFIQWVIEDDFINGRPALENVDVEMVESVLPWEEAKIRILNASHSCIAWAGTLIGLSFIDESTRQSAIKQMAWNYVTQDVIPSLSPSPLDLEQYRDVVLARFSNPYIQDTNQRVAADGLSKIPGFITPTLQECYQRQQTPAATAVLPALFSYFY--------------------------------------------------------------------------------
120 UniRef50_Q9XBD5 Putative mannitol dehydroge... 394 1e-108 1 33.3% 8:481 3:437 -------PRLSRSTYPAASPRAGivHLGLGAFHRAHQAVFTQEAMLAEPGDWAICAVGQRNPAVR-DAMSTQDCLFTVTERDAEHEDLRVVDSVRDVLLA-SEQPDQVTAALADPATRIVTITVTEAGYRHDPATGRLRADDPEVAADVAG-RPPRTVIGQLIRGLKAREHSG---LTVVPCDNLPDNGRLVAGLLRDFCVLSgpELAERIAEQVRCPSTVVDQIVPATTDADIANVASLLGLLDRAAVVGETYRQWVIEDDFAAGRPAWDKAGVRLVADITPHQAAKLRLVNGTHSALTYLGLLAGCTSTAEVATRPEFARYAERLIREETGASLARFGIPVD--IDGLLKRLANPRITHRLAQIAADGVRKLPQRLLDPAAELLESGAEPRMICLALAGFLRHER------------------------------ETPDCLFAAR----PALRDSRVFGELLTDAMHQLDRNGVLTTLR-----
121 UniRef50_B8HCK0 Mannitol dehydrogenase doma... 394 1e-108 1 33.5% 2:476 11:486 -TPVSEAAAPAVPQLSraKAPVRIVHLGLGAFHRSHQAWYTQHAGDAA--QWGIAAFTGRRPDA-AEALSGQDGLYTVVERGDAGDTFEVVSSIVEAVDGA--DAGRLTALIAAAGTAVVTLTITEAAYGL-GADGQFDRKAQGVAADLQELSapATPVGRLVHALAARKAAGAGPLAVVCCDNLSNNGTVASTAVVGMAEAWNPELAAWIVENISFVSTSVDRITPRTTDADVESVKAACGYFDNSPVVAEPFRNWVLSGDFPAGRPRWEDAGAVFVDDIEPYENRKLWLLNGAHSLLAYAGQLRGHATVAEALADPVCLAAVERFWNEAEANLtaAHGADLqaYREQLLARFRNARIAHHLTQIALDGSTKLRMRAVPVLTAERDGGRSGAGAAAMIAAWVAFC--IDATGRGRTVQDPLSDGIEAACALAG--ADRVRALLALLSV---PLSQDDAVVELVDGLAGGFARQGA----------
122 UniRef50_A8LED4 Mannitol dehydrogenase doma... 393 1e-108 1 29.6% 3:471 28:485 --PAAVARPLSRPGGdrPAARVRILHLGLGSFFRAHQAWYTDRAPDAR--QWGIAAFSHRRR-GLAHALTAQDGLYTLLTRGAEGDRFDVISSLAAAHAGS--DHDAWLAYWRQPALAVVTLTVTEAGYACDP-DGGLDLARGDVAADIAALRTDptAPARLLAGLHARARAGRSPVATVPCDNLAGNGAVAGRAVRELAAATGRPELVAAADGASWVTTMVDRITPGTTDADGAAVRAATGRDDAVPVVTEPFSEWVLSGDFPGGRPEWEHAGARFVADLTPFENRKLWLLNGAHSLLAYAGPRRGHVTVAQAVADPRCRGWLIE-WWAEASRHLSMTRTELESYQHALLERFENPRIRHLLAQIAMDGSLKLPVRILPVLRAERARGVMPRAGIRVIAAWMLHLRE-----GTASVRD--AEAGRSVAAARAPLPEAASLVL---DLLGPGLGRDGELVAALAAQVTEL---------------
123 UniRef50_A4FJI1 Fructuronate reductase n=1 ... 392 1e-107 1 35.0% 21:477 23:481 --------------------RTGIVHLGLGNFHRAHGAVYTAQAMAAAGGDWGIRGFA-HSSDRVVAPMRAQDNVYSILQLTERGAEAGLVDVHRDT-GVAAQDPAAVVDAIADPAHRIVSLTVSEVGYTRDPATGRLALDAPEVAADLTAGSTPRTAVGMIARGLEQRAASGE-PFAVLSCDNLQSAGDVTRAVVEEFLQAAgdDVLSFVSSSVSFPNGMVDRIVPRTTDEHSRIVADLLGVQDLCPVPAEEFTMWVLEDDFAGGRPAWDLAGATFSNEIEAYEMVKLRLLNGSHSLIAYLGILSGAPTIDVAWGQDFVREAVLNGITDDYLPTFTPpgFDADAYVSELDARWRNPLIGHATTQVGTDGSLKLLQRIPNAALFHLRRGDMPHHLALCIAAWIACvaGFTPEPLAERIVEPARDRLAAAVDGAVTVADHVRRIM-NGGFFPDALAEQDAFTVRVADLLTLVVRDGVR---------
124 UniRef50_B6R3S8 Altronate oxidoreductase n=... 392 1e-107 1 22.2% 17:484 12:481 ----------------RPRPTPRVIQFGEGNFLRAFMDWKIDRMNERAGTDFGVVVVRPIDGGIPFS-LNETDGAYTAVTRGVdvSDVRQVACIRKEMSAVSEWHE-VLALARNSDFTTVISNTTEAGITYLPDCK---------LQDEPPVSFPAKVTRLLLERFNSFGGSSAPGFQFLPCELIEKNGGTLEEIVLQHARDwpTEFINWISTHSAFYNTLVDRIVPGYPRGEAKTFEAELGYEDPLMVTAELFHFLVIEKREDQPELLLPLggTLITSNADGYKERKVAILNGAHTGFCPLALLSQTETVQSAIEHPVGRAFLEGMLQEEIIPFLSLPKDELSAFSDEVLRRFSNPYIKHRWHDISLNGIAKFQTRNLPRFESYIAAkkPPRYMALSLAAWLIFYTGAFKHAEELPArdEVLERFKTllQVTEGTDTMIRAFLSEEAFWGKSIASDA-LVALILEALAFLQAE--PFTLDRLA--
125 UniRef50_B1LA83 Mannitol dehydrogenase doma... 391 1e-107 1 25.7% 9:486 18:536 --------GVRPPYFDLDEvqPKWVHFGGGNIFRGFVAAVLQNLLEEGKEDTGINVIELFDYEVIDKVYKPYDNLSIAVTIKPDGdeKRIIASVMEAldPLHPDWERAKEIFRNPSLQLASLTITEKGYNIEDQAGNL---FPQVMEDMKnpVSPQTSMGKVAALLYERFKAGRLPIALLSLDNFSRNGEKLYSSVKRISEEweKDFIDYLEKDVAFPWSMIDKIVPGPSEFIKEHLEKLGIEGMEIFVTSkpfqYLVIEDSFPNGRPKLEGanVFLTdtVEKAERMKvtCLNPLHTALAIFGCLLGYKKIADEMKDPLLKKLVEGVGEEGIKVVVDPGIINPREFLNEVInrLPNPYLPDTPQRIATDTSQKMPIRFGETIKAYHErpRNLKYIPLVIAGWCRYLMGIDDEGKEMQLsdPLLENLRSYVSKIksTDDHLKPILSSQQLFRVNLYEV-GLGEKIEELFKKMItrAVRKTLEEVVGR
126 UniRef50_P58708 D-arabinitol 4-dehydrogenas... 391 1e-107 1 30.8% 19:473 7:459 ------------------ARAPVLLHIGAGSFHRAHQAWYLHRVNAapGERWTLTVGNIRdmHATLAALAAQQGAYTLETVTPQGERaeTIRSIARVLPWSAD-LAALINTGADPACRIVSFTVTEGGYYLDEHD-RLDVTHPDLAADLRGAR--STLYGALAALLAERRQRGAGPLTLQSCDNLRSNGARFRAGMRAFLALrdAALLAWFDANVSCPSAMVDRITPRPTDDVRTRVHAATGVDDRCPVMGESFIQWVIEDNFIAGRPAWEIAGAEIVADVHPYEEAKIRILNATHSCIAWAGTLAGLTYIHEGMRDAAIYRFAYDYVTDDVIPCLTPSPLDLERYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLAECFARGADPVATAVLPALFLGFLEGWARGTLPYVYQDGVMDG--AAARSIVEAPDSVAAFCSDRQLWGS-LAGRDALVQAVRAGRARVEA-------------
127 UniRef50_C9L6K8 Mannitol-1-phosphate/altron... 390 1e-107 1 27.2% 7:484 16:516 ------AANIALPTYDIEKIrpVWVHFGAGNIFRIFMGGLADTLLSAGEMQTGIACVETFDFDVIDKIYKPFDNLVLAVTLKSDGsdKKVLGSLTEAYKASPDFPerLEEIFINPSLQMVSFTITEKGYALKDSS---------------------SAISLVCALLYKRYKANQAPLALVSMDNCSHNGEKLQKAVLDTAKEWqeGFLSYleKRISFPWTMIDKITPRPADSVCKTLERS-GVEnaPFVNAEAPQYLVIEDNFPNGRPPLEKAGVYLtdTVNKVERMKvtCLNPLHTALAVYGCLLGYTSIADEMKDCELSKFVHEIGLTEGMPVVTDPGisPSAFADEVInrFPNPFMPDTPQRIATDTSQKVGIRYGETIKAYIKKYGTASKLtlAIAGWCRYLIGVDDKGNPFELsdPMLPMLTQSLRGikSYCGQLKTILSDASIFGVDLYK-AGIGEKIEEMfeEIAsgGVRNTLKKYL--
128 UniRef50_C0VU95 Possible fructuronate reduc... 388 1e-106 1 33.4% 25:449 5:385 ------------------------VHLGLGAFHRAHQVWYTHEA----DPDWNYVSFTGRSA-RMSDLLTAQDNKYTLVTRSKDGDTFDLIETITETQPAA--NVERLMELMASSDVKVVTLTITEAGYDDTSDN---------------------SAPQRIAKGLTARKASGAGPIAIMSCDNVSGNGEKCKQAVYAVA---DDELKAWMDENVTFPTTSIDRITPATTDELIELVEKETGFADKAPVVTEPFASWVIEGEFPAGRPNWEKAGVEFVEDIEPFEHRKLWLLNGSHSLMAYYGQLKGHETVADAICDPAVHEKVEALWDEAAQGL----PMDVTDYRASLIERFENPNIRHNLAQIAIDGATKQQNRAVPI--YGIAHG---DGAAFSIAAWIVYCLTTED------IKDTRADEINEAKGQSDPVQAlvLGIDADEKI-------------------------------------
129 UniRef50_B2VCG7 D-arabinitol 4-dehydrogenas... 386 1e-105 1 28.0% 18:474 5:459 -----------------NDKKSNWLHLGAGAFHRAHQSWYLNQLHQQGDNSWALSLANIRNsqKTLQQLAKQQGRYTLEIISPEGEIvqPIEAVENVILWD-EGLKSLVAVGASAATKIISFTVTEGGYFLDD-DGELDLEHPAIQADLAEQQETSTLYGALVKILRERMRNETGPVTLLNCDNLRDNGDSVARGLSQFVNAkdQQLLAWIEQNTSAPNGMVDRITPKFDAALFERLAEQGIENDGAPLSCEAFSQWVLEDKFIAGRPALENAGVEFVSSVTPYEEAKIRVLNASHSGIAWAGALLGKKYIDQSLQ-PLIKRWMSDYVLKDVAAALQPCDIDLAHYGETTLNRFSNKWVRDTTQRVSSDSIAKLQQFIVPTLKARYKQDATPAATLILPALWFRFMQQHHAGTLPFDYEDRALDEV--PFADIFNADDPLLAFTQQKKLFGS-LAGRPELYRDLSAAVDNVDKG------------
130 UniRef50_C7R2P7 Mannitol dehydrogenase doma... 385 1e-105 1 32.7% 18:467 19:478 -----------------AQRDPRIVHIGLGAFHRAHQAWYTQHAND----NWGIIAFTGRSPHA-ATQLTQQDGIYTLVTRSAQGDTHEIIDTITAAHDG--NDLTTLTAHIAAATTAIITLTITEAGYHCIMGtpTLNLNDPHIDTDITTLRTltTVPARIVLGLAARRDADAWPLAIMSCDNLPHNGAVTRAAITTIAHHVDPTLAQWITDHVSFVDSSIDRITPRTTDTDKRTVAHDTGYLDHTPVITEPFSSWVISGDFPAGRPAWENAGAQFVTDINPYERRKLWLLNGAHSLMAYAGQLRGHTTVSDAMLDPEVTTWINEFW-DEAARHLTEPDLDIPAYRVALTQRFTNPRIAHPLAHIAHDGSLKLAARAVPVYQAEHAAGRSGTASLRLLAAWCDHLVIQHRN--VIPIHDPNADALTHIITAHANTPRELATTQALITVLDPDLAANTTALTAIHTM-------------------
131 UniRef50_A6W9X4 Mannitol dehydrogenase doma... 384 1e-105 1 35.4% 4:478 15:481 ---ATLPSA-SRPLLDPRQLRAGVVHVGFGAFHRAHQAVYTEAAAAASTDPVGTVVVVPGSA-ATASHLLEQDGLFSVTELSGDPGVPRVVASTTGVVRGW--DPDAVASLLLDPGTSVVTLTVTEKGYRRD-LRGGLDVTDPALADDLAGGRP--TAVGLLARALDARFRANGAPLTVVSCDNLARNGEVTSRVVREYVErwQDavLQWLQTAVTFPSTVVDQIVPAATPGVLDSAAQALGVRDELAVAGEPFRSWVLQDDFAAARPAWELAGARFVDDVAPHQLMKLRLLNGSHSALAYLGLAAGCATVDEAVATGWGSTLVQRLGG-EVAPTLPVPQEQVREYCHALGQRFANPGVRHRLTQIGDDGAAKVAERWFTPLRELRAARKPVTVLIAAVAAWAHATRP-DGEAQLFGTTDPLSAALADCWAHERGGPPVVAGLLRTAG--ADDLAEDHALVDAVAGHLPAL-ARGVVE--------
132 UniRef50_C0QWB1 Mannitol-1-phosphate/altron... 383 1e-105 1 25.8% 8:484 17:540 -------SDIKIPKYDIKQIrpTWVHFGAGNIFRGFIARIADTLLNDNIIDTGIIAIDtdDYEMINKVYKPFDNLTLLASIKSSGddKKVIGSITDVVHAdiNSYEELKKIFISNSLQVASFTITEKGYSIKDLNGDYNIT---VKEDINnpLKSKNIMSISAAMLLERYKNGAYPIAMLSIDNCSNNGDKLKSSIIEIAREwdEGFIKYLEdkTAFPLSMVDKITPRPSEIISKKLEE-TGLEeaAFVNAEVPEYLVIEDLFPNGRAEFEKAGVYVTdtVQTSEKMKvtCLNPLHTALAVFGCLLNYNFIYEEMKDPLLKKLVEKIGYDEGMKVVADPKinPRDFIKEVieRLVNPYIPDSPQRIATDTSQKIPIRYGETLKSYIKNGLYTSSLilTIAAWLRYLMGIDDNGKTMEIsdPMLEELQKHikNKDSIGNNLKPILSNKVIFAVDLYDKenLGEKIEGYFREMieNAVKECLKKYI--
133 UniRef50_Q0FGE2 Mannitol-1-phosphate/altron... 383 1e-105 1 25.0% 3:474 2:470 --NNISLPKIHSTNYNKNECEIGIVHVGFGAFHRAHQAVYMDDYMSknDLRWGIAAVNLRESETAHFEKTVqnGGYLIKSYSSDGHdvRMVRSHIGFYDWTTD-IENTQNLLAVETVHLVTITVTESGYYTN-AYGQLDINEPTII-DEINNSNLKTIYGYLRNAINKRIMAHGKPITIACCDNIRQNGLMLKQNLISYLKACGDQllDWVQKNAYFPCSMVDRITPQTSILLQEELSSLIGHEIYSPIMAEDFSQWVLQDISLGTLPALDIVGVTITKDIDPYEETKIRVLNGGHTALTYMAALEKMITFDEAMRSHQLLEHFRCFQVNEVLPALLLdpFSKNDYLAKIEERFCNKAIGDTISRICADGMAKFPIFIRPTLEGCLQQGIVPHFSIKSIASWHQFCLHVAAGKIDFKYVEPSWAFLETIIGT--------DEFITCQQLWSDIPNKYPDFTINLRNEIFEMEKK------------
134 UniRef50_C6Y3U9 Mannitol dehydrogenase doma... 383 1e-105 1 20.7% 2:485 8:499 -LNSIKPNQVVAPDEKIFNLPEKVLQFGTGVLLRGLPDFFIDKANKKGLFNGRVAVIKSTSKGGT-KEFDDQNGLYTICVRGIevEENIISAAISRVLTAD-QDWNTILDIAASPLLKVIVSNTTEVGIQLVEES--------------IDQSPPQSFPAKLLAVLYARYKALGAAAAADitELISDNGKKLEAIVLQLAakLDEAFLTWLNAHVHFCNSLVDRIVPGKPDAtlANLETELGYKDELVIMAEPYRLWAIEGGqvAELLGLEAagVIVRPDIEIFKELKVRLLNGSHTLTSGIAYLLGIDTVTKAMNNSLTRNYVNELMMQEIVGAIPYdpDEAIAFANTVIDRFANPSIQHLWINITFQYTMKMKIRILPVLLNYYKLNQkpAHIAFGFAAFLLFMKSARKDGdeYAITDDEAAYFYNIAQQNES--EYVNLVLADSKLWGTDLSSLQGFNETVKENYNNILKHGVADALARLEE-
135 UniRef50_A3JTC9 Mannitol dehydrogenase n=1 ... 383 1e-105 1 34.6% 22:434 2:395 ---------------------PQILHFGVGNFFRAHQAAYT----ALAGGDWRISGVSMRS-DAMRRAMAADNFAYTLVVEGGPQSEFQVIDVIDDILLAPTQ-PDEILTKLADADVQIVTATVTEKGYHL-AANGELELGDPDIQHDMNG--TPKTLIGFLAIGLSQRK----TPMTILSCDNRMDNGRVLERAVKKFASAAGLN-INW--NLFMFPNSMVDRITPATTDELRNRVAAM-GYPATAPVPTEAFSEWVIEDNFATPRPDWAAAGARFVTDVAPHEMRKLRMLNGAHSMLAYQGVLAGHEFVHQAIADPTLLATTQGLM-AEAALTLPVELQDMSayGRDLIARFANPSLAHSLRQIAMDGSQKIPYRFLQSRTALREMNMPSPCLDAALQAWMDFCRAETKAGR--QINDPLGRAIADASTRDD----------------------------------------------------
136 UniRef50_Q5WIW3 Altronate oxidoreductase n=... 382 1e-104 1 23.2% 21:459 22:473 --------------------KETIVQIGEGNFMRGFIDWMVDQLHQQRLYDGRVAAIQPTPHGKIVPVLQAQDGLYTVILRGkdgdEAEVVQSIARGINPYND-WEEVKKLARSPDVKWLFSNTTEAG---------LVYQQERYEKDKAPLSFPGKVTAFLYERFLAFAGALEAGITLVPCELIEDNGAVLKDIVETIAEDWEleFGQWLRKANVFCNTLVDRIVTGFPHGEEETWANRLGYEDRLLTVAEPYHLFVIeeRPLDERLPFEQAGLNvwEPVALHRELKVRLLNGLHTMMFALSFLAGEDTVKGALHSPRLRRFIERGLEQELIPVVNAPEEEKQAYAASVIERFENPFLAHKLTDIGLNAIYKFKTRLLPALEAHEQQDNEPSQLLASLAALLVYMKPQERdgRTYQinETALALLEATwaGEATLAETISTLLQADGLWGRDLSRYSE---------------------------
137 UniRef50_C1QE60 Mannitol-1-phosphate/altron... 381 1e-104 1 26.5% 9:484 19:541 --------NIEIPKYDIKQIrpTWIHFGAGNIFRGFVARIADTLLNDNVINTGIIAVDtdDYEMLEKVYKPFDNLTLLASIKSDGndKKVIGSITDILHAdiNYYEELKKIFISDSLQIVSFTITEKGYSIKDSNGNY---NKIVAYDIEnpKKAKNIMSIACAMLLERYKNGAYPIAMLSIDNCSNNGDRLKDSIIEIANEwdNGFIEYLEDntAFPFSMIDKITPRPSEIISKKLES-IGLEdaGFVNAEVPEYLVIEDSFPNGRPDLTKAGVYITdtVKNSEKMKvtCLNPLHTALAIFGCLQNYDFIYNEMKDPLLKKLVERIGYDEGMKVVINPKinPMNFIKEVieRLVNPYIPDSPKRIAADTSQKIPIRYGETLKSYVKNGLDTSSLiiTIAAWLRYLMGIDDNGNTMEIsdPMLEELQKHIKNIksVGDNLKPILSNKIIFACDLYDEknLGNRIEEYFKEMIinAVRECLNKYI--
138 UniRef50_D1YCS2 Mannitol dehydrogenase C-te... 380 1e-104 1 25.8% 2:482 10:526 -GPALADAGLALPLFDVGEMrpRWMHIGPGNLFRVHIARLAQDIMNSGAEQCGIAAIAPRNPQRLDRGLTDHDLLTLGVTSHADGHtfGVIASISEGlyRRDDDFRRITEIACAESLQLITLTITEKGYQLNGYDGSYQDAVVKDLGRDPESDRMSTAMGLVTALLVQRFHAGATPVAVVSCDNFSHNGDMLRTSVLTIVAEwdHRVVEWIAEKVEFPISVIDKITPAPSQKVAEQLASM-GFEdaGFVNTEPAEYLVIEDRFPNGRPELEKAGVYFtdTCHRFERMKvtCLNPLHTALAITGVLLRKPTIDEAMKDPGLVGLVHRLGWQEGLLVVSDPgiDPKEFLREveERFPNPFLGDTPSRIATDTSQKIPIRFGETVKSYLADdaSLRAIPFVFAAWCRYLMGIADDGEPVELsdPLREQLESVVSggDDDSKVISPILSRADIFGVDLTMTP-LSEVVERFFIRLTagAVRSVLDE----
139 UniRef50_C7PPZ6 Mannitol dehydrogenase doma... 377 1e-103 1 23.8% 19:484 24:498 ------------------DYPERILQFGTGVLLRGLVDYLVDKANKQGLYQGRIVVVKSTGGDTT--EFSKQDNLFTTNIKgeLVNQVLINASISRVLQSNAD-WEFVLQAVRQPALQTIISNTTEVGIQYVEE-----------KIDGVPSSFPGKLLAVLWERFQYFKGASHTGFVIVPTELVVNNGQLLKEIVLKLAarLPATFLQWIEEDNHFCSSLVDRIVPGKPKE-LAVLEEKAGYTDGLWIDTEPYLLWAIedDRVKDILGFHQTdmLIARDITPFREQKLRILNGSHTISVPLGYLSGLNIVLECMEDANMRAFFRTVILEEILPTIKDICPQAPAFAEDVLDRFANPNIAHKLLSITFQESMKMNARNVKTirYYEKFQALPASMCLGFAAMLLFLRPEKLDneYYTITDDNIAIFAEYwrGGDAIAEMVQAISADQRLWEADLSQIPGFADTVTAHLQGMLQEGVKSYADSYS--
140 UniRef50_A6EKW0 Altronate oxidoreductase n=... 376 1e-103 1 18.8% 1:483 1:491 MLNDISGEHLQSPDLSQFNLPEKVLQFGTGVLLRALPDYFINKANGQGLFNGRVVVVKSTSKGD-VQSFQNQDGLYTICVRGLevEENIISAAISRVVSAEHD-FAEILTIAGSKELTLIVSNTTEVGIQFVPED--------------VHQSPPSSFPAKLLAVLYARFHadEADIVIVATELIPENGRRLHDIVIELCrkLNNRFIRWIDRRVYFCNSLVDRIVPGKPasVQEEVQGLLGYEDQLLIMAEPYRLWAIedDKIAALIGLsdAGLIVTPDIEIYRELKVRLLNGTHTLSCGIAMLSGIKTVGQGMSEDSLKLYIKEVMYKEIISSIPYPVdeASSFADAVSDRFANPYIEHLWSSITFQYTMKMKVRILPLirFYEIFNEVPKLMAFGFAVYLRFMRVNhfDGNNYLINDDQAEWFCQKCEL--PDQEYIHAVMIAESLWGADLSRCIGFEVAVADYYHDISKEGVLQCLNSI---
141 UniRef50_C5RJ64 Mannitol dehydrogenase doma... 374 1e-102 1 20.9% 21:474 25:487 --------------------PIKVMQIGEGNFLTSFFDWMLYKAIEAGKYEGSVALTCPLDFDKKINILKEQDMLYTVTQRGfeVDESDIISVFSKVFN-YNVDWNSFMEIAELESLEVIISNTTEAGLAYKE------VELDKVSVDGLYP-------GKLTAFLMHRFEnkTKKLLIFPCELLDDNGKVLEEMVKKHAEstSDEFKTWVNESCVFLNNLVDRIVPGFPRENTEAYFEKLGYIDEAASVCEPFFLWGIEGSEEYDklPLKSAgvKWADSLYDIHLLKVSILNGSHTLITPLGILKGFERVDELVEDPEEKAFLNEALQNEIIPSLK--NEDAEGYAKTILQRFRNPHLKHKLESISMNSVSKFVNRDLPTVKAYIEDNNspKNMVIGLAGLLRFYqgHNFKGKEYPVFD-VINVLDFMCNMNKenQNYVKAILSNTELWGEDLTKIEGLTVAVSEALESLERK------------
142 UniRef50_C9C0V4 Fructuronate reductase n=16... 373 1e-102 1 24.0% 3:486 12:540 --PELSQKEVEIPHFDRASLrpVWIHFGGGNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLIlvVMPSSGEFVKRILAATADSLYCHPdhFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYI--GPIAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAKEWQKefIQYleEIVAFPWTMIDRITPNPSLSVSKMLAKEggNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTdtVDKADTMKvtCLNPLHTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPgiDPKIFLEEVItrFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMedPQTLVFIPLTLAAWLRYLIGIDDQGKpiPSPDPLLTDFQHKlqDTSHIHEKMAPILSNKEIFGVDLYQ-AELGRKIEEMFIKMVanAVRKTLQDYLQE
143 UniRef50_C6JE46 Mannitol dehydrogenase ross... 373 1e-101 1 27.4% 8:485 17:538 -------AGITLPSYDVEAVspVWVHFGIGNIFRVFIGGIADGLLEEGVLDRGITCVETFDYDVVDKIYDPYDNllSVILHGDGTREYKVVGAFAEAVKAQseQWKRLKEIFTSKSLQMVSFTITEKGYALQKADGTW---FPFVEADIKnpDKAVGAMAVLVAMLYERYKAGEYPIALVSMDNCSQNGAKLRESVLTMTEEwdEGFVNYVSDevAFPWTMIDKITPRPSEQIAADLEN-LGVEnaPFVNAEKPQYLVIEDSFPNGRPALEKGFGVYMAdvNLSERMKVtcLNPVHSATGPLGVVLGYDLFAHMLnnEDMMKMARMIAYDEGLPVVADPGisPQAFVDELfdRFPNEYLGDTNLRLAVDVSQMVGIRFGETIKAYVQKFGDASRLtlGIAGWLRYMLGVDDEGNKFELadPMNEELQEQFKDIVVgkDQLKPILSNERLFFTDLYKD-GVGEKVEDMFREMIagAVRATIHKYVG-
144 UniRef50_D0YQL5 D-mannonate oxidoreductase ... 371 1e-101 1 27.1% 4:482 12:536 ---AASLPQVSVPGFDVSTMqpRWIHIGPGNLFRCFPARIAADLLERGE-NWPITAVAPRDLEDMEFQLPHHDLLTMKVTLNPDgqDYRVIAGIAEAIGVGTtdMERLFRVVRDPGVELISYTVTEKGYGILDGSGELQAgaAMEDSDPKTLEHCQASTMVLSalLLERFAAGGTPITMLSFDNFSHNGDKLRDSVLTIARAwpAGFLDWLEdkVAFPITVIDKITPRPSPEIATKLAN-LGFTdaGFVNTEPTEYLIIEDKFAGSRPAWEDLGVQVVArcDDFENMKVtcLNPLHTALAVSGCLMNFPTIDAEMRDPALVALVHELGWKEGLPVVVDPGvkPEDFLREVLErfPNRYLPDNPARIAMDTSQKIPIRFGVTIRKYLETGRdlHAMPLVFALWCRYLLGVRDDGSPFEpsDPRLTELSAHVAgsTAVHEALAPILSDASIFGLDLYETP-LAEATEQYFQRLIAraVRETLDK----
145 UniRef50_C8WWW7 Mannitol dehydrogenase doma... 371 1e-101 1 22.5% 18:483 20:478 -----------------RAMPIRVVQIGEGIFLRGFVDWLVHRLNESGTFQGRIAVVNPRPSGAhvHQFQEQDGLYTVLVRgrPVENAELVTSVARAFDSTRE-WAQVLQLARDPLVEIAVSNTTELGVRYEPV--------PRPMSDAPPGTYPAKLTQYLHERYLALGWQETSRLIVVPCELIDDNGQQLRSIVERHAADwgGDFMRWLRDRVEFCDTLVDRIVTPYAGDPP------LPYEDALAVTVEPYYLFAIRGSelKALWPFEEVgvHYADDIRDFRLQKLRALNGTHTALANLGLMAGLETVLEVMQHPTLSAYVRHLVHGEIVPavSRPEM-LRDFAHDVLERFQNPYLEHKLRSIATNAVSKARIRLVPTLLDAVERLGDARRLTAAVAacLAYRPGMERAAEP----DPAADRLRALWQ--DDLGASAHAILSDAELWSADLTQVPGVLDGWIRFVEMALREGPVQAVASL---
146 UniRef50_Q02XT0 Fructuronate reductase n=7 ... 371 1e-101 1 24.8% 8:482 18:535 -------AKINIPKFDQGKVapVWVHFGGGNLFRCFHAVVAQDLLNQGELNSGIIVAETYDDEVIEKIYHAYDNRFLSVTMKSDGtdKELIASVSESFyeNTEGWAHLTKVFENPSLQFTTFSITEKGYSLRDSKDQL---TPLALEDMQGRSKPKTNMGAITYLLYARFKAGKFPIAMVSTDNFSENGLKLQEAILTIAKAweQDFYDYLikKVSFPWSMIDRITPNPSEKVAELLTAD-GFEdaPFGNTEEVHYLVIEDAFPNGRPALEKAGVILTdtVNDADQMKVtcLNPLHTALAIFGSLLDYHSIWEEVANPDLLALIKNLGYGEALPVVKNPkiNPTEFIDQLlkRLPNKNIPDTPQRIAADTSQKIPVRYGVTIGHYIANPreLEFIPLVIAAWCRYLIGINDELESFSPsdPLLEELQAFVAeqKEIHEILKPILSNHQIFPHEMYQ-TGLAEKIETYFEEMIqgAVLATLQN----
147 UniRef50_C5BXX0 Mannitol dehydrogenase doma... 370 1e-101 1 31.5% 8:473 18:450 -------PGVRGPLVEPAAV--GVVHLGIGAFHRAHQAVYTERAAaaGEREWGILGVTGRRPDV-ARVLDASGGVYGVLVRDGADVSVDVVGAVVEA-ASPDQDAERVVAAIAAETTAVVSLTITEHGY----------------------AGPPFSPPIELLVRGLRRRAAHGAPLSVLSCDNLVDNGAVLRRIVRA-AVSGDDGVARWVDDAVRFPRSMVDRIVPATTAEDRRAAAVLTGFDDAGLVVAEPFSEWVIEDDLAERRPRWELAGARVVPDVEPYERLKLRTLNATHSLLAYEGEARGHTTIAEALDDDELARRVEALMAESGLTLEQPPGIDVVAYRAEVLRRFRNRGMRHTVAQIGHDGSRKLPIRVGGTIGDLVAQGVTPDATARVLAAWAVHLRRG-------AVVDPLADELQAAARAARDAVELAELVLRLPGIVPDAVAGRRDVRDAVAAHTAEILA-------------
148 UniRef50_C7PV24 Mannitol dehydrogenase doma... 360 7e-98 1 21.7% 17:486 13:477 ----------------RAVLPEKVLQFGTGVLLRGLPDYFIDKANKAGIFNGRIVVVKSTD-KGNTDAYSEQDYLYTHCIQgrRVEEYVVNDAISRVLSATGE-WEQILECAADPEMEIIISNTTEVGITLT--------------ADNIDAAPPASFPGKLLAFLLRRygDINKGMVIIPTELIPDNGTKLQHILLELAQqlEAAFINWLSAANHICNSLVDRIVPGALPAAAQAAVEalRYSDQLMIMSEPYALWAIETSSERVRKVLSFagVVLAPDINIFRELKLRLLNGTHTLSCGLAVLAGFNTVKEAMEDTAMESCISALAQHEIVPAITDVTIREDafAGSVLDRFRNPFIEHRWQSITMQYTSKMKMRVIPVirHYQRLDEVPALMALGFAAYLLFMRDG-------EVTDDYAAYFKEKWQKL-EPAVLVQTVLKDTALWGVDLTQLPGFSHAVTIMMGALLTEGAPSLIRRVSEE
149 UniRef50_Q03U13 Fructuronate reductase n=7 ... 356 8e-97 1 25.1% 8:485 18:538 -------AGIKVPTYDQAALkpRWVHFGGGNLFRAFHAAIANTLIEKGELDSGVIVGETYDDDVVKDIYQAYNNRILRVVTKADGndKELFASVAEAYfsHEDDWNNLFDVFKKDSLQVVTFSITEKGYNLRTVNGDldLTKADIA---NGPEKPRGNMAGLVSLLLARFNNGKAPLALLSTDNFSQNGDRLKESVLTIAKGwgADFLAYLQdqISFPLSMIDRITPNPAEAVGDKLAAA-GFEDHEIvnTEEAHYLVVEDAFPNGRPKFEDAGVIVtdTVNDADEMKvtCLNPLHTALAIFGSVLGFDSIAKELQNKDLVALIKQIGYVEGLPVVTDPkiNPKDFINQLvkRLPNPYIPDTPQRIATDTSQKIPVRYGVTIKHYDERDgtLEFIPLTIAAWFRYLMAVNDEGASFEPsdPMMADLQKYVGDIkdVHAHLKDVLTNTSIFGQDLYAV-GLGEKVENYFKQMIagAIVATLEKALA-
150 UniRef50_A4FJT9 Mannitol dehydrogenase n=1 ... 350 6e-95 1 28.7% 48:472 2:389 -----------------------------------------------ADPDWGIAAYTFRNTE-LPRTLAEQDGLYSLQVRGEGEPRAEIVDAISRA-HPGSE-TDQWLADLASPDVTLLTLTITEAGYRLSGDQDG-------------------TAIGRVLAGLRGRHRASGAPIALVPCDNLPGNGGVLREAIRTAAAGEAPDFRSWIEDHVSFVDTVVDRITPATTEQDVTATARLTGFEDRAPVVTEPFSEWLLAGDFPLGRPAWENSGARFVDDLAAYEQRKLWFLNGAHTLLAYAGPALGCATVDEAVRHPVLARLT-ASWWDVASRHASLPEEDLADYRQRLRQRFSSRGVRHNLLQIAADGSQKIPARILPVLRAERAAQRMPDAPVAALAGWLIHLRDR-------PVSDPRADELVSLAHSADAPRRVLSAL-------DVTLANDRELVSAVEDYVEHLR--------------
151 UniRef50_C7MAX7 Mannitol-1-phosphate/altron... 341 4e-92 1 29.0% 23:471 11:420 ----------------------RLVHLGIGNFARAHTLHATDVA-----GGWSVVAFTGRSA-TMADALNAQGGRYGLIVRGAEGDEVSLVDVIDEVHPAS--DVDTLVRLLADPFTAVVTLTITEKGYA-------------------AGSDPATSAPARIALGLKARREAgtEPIALVSCDNLTGNGEVLGQAVL---AELDEETKAWFPDHVDVISSMVDRITPSADENASETVRAQTGLADSVPVVTEPFTEWVIEDRFRGRRPEWEKAGVQFTDDLEVHELRKLRLLNGAHTLMAYAGQVAGVQRVDEAIAHREVRALVEQLW-AEARATLPLPAAELDAYTAALEERFRNPRLADNLIRIAADGSVKLPVRALPVIA---ERGGPEQAPGEVAAVAAWTAWVTDRVRAGEEVQDPKSEAIAA-AASLEDTTERVSSLLAL-----LDVPAIDPLVDAVLAEEQRL---------------
152 UniRef50_D1BXA2 Mannitol dehydrogenase doma... 332 2e-89 1 21.3% 18:481 21:511 -----------------PERPTTILQFGGGNFLRAFVDLMVHDANRAGVMNAGIAVVFTTPnnGTFELLRRQDGRYHVLLEgePVREVTLVESVTTAVHAHRE-FDAYRALYLSPELTTIVSNTTEAGI-------------VWVEGDDLTAQPPASFPAKVTALLHDRWeaPDKGLRIVCCELIEDNATTLREYVLRHAAAAGLpfVAWVETACSFHDTLVDRIVPGFPRDEIDAVQAELGYRDDLVVKGEHFGVWAIATGEPGGplPLDRAgvEFLADIRPFRAKKVRILNGLHTAMAAVGLLAGRNEVSDAVANLTIASYLGHLLHGEVLPSIPEYSAslAEFADRITERFTNPSLHHRLADISLNSISKWQARNLPVALDAWGAGREAPLTVLAFAALAVLYSGRGFDAArfEVRDDAavALVRDTFPAEGTDDDVERWLraAGFFSADDAAdaRLAAEAAPLARTILEEGITVTLK-----
153 UniRef50_A6DPG6 Tagaturonate reductase n=1 ... 332 2e-89 1 20.8% 20:480 1:453 -------------------MKNKILQFGSGVFLRGFWGWMVNELNKNENFDASITMVKLTPRGDL-SQFKETSGLYSllLNGEVIDTNEEIDIYQRFIHPYPEWVEFLL-TAEEEDLQIVVSNSTEAGIVYK--------------QCLFPNECPETYPAKLCAWLYKRfqSSDKAPLILPMELIESNGDKLQEIIIKHANDwdHNFITWVQKDCDFRNTLVDRIVTKGDKNDA---------------CVEPYHLFAIEGEEAEEILPLKKAGVnwTKNLPAFRETKVRMLNGGHTSMIYAAILSGETIVADALEKLEIDQFLRSILLDEVLPTLEAKGGdlTDYAEAVIERFKNPFLNHEMINIALNSASKLLVRILPSFNDSTKLNKkpEKLSKAIAAFFWFYRGseSEGLTYEFADDAKAMSAIAKCDTSSAANFAKAILACSA-WKGAFNKHPDFEATLTKILEEFEEKGLKASL------
154 UniRef50_C5C1F0 Mannitol dehydrogenase doma... 331 4e-89 1 32.3% 24:444 1:402 -----------------------MVHLGLGAFHRAHQAWYTHRANLAASGawGIAAFTGRRPDA-ARALAAQGCAYTLLVREPDGDAAERITSISGAYDGA--DTAAWRGAVANPRVAVVTLTITEPAYGA------------------------TSAMRRLADGLAARRDAGAGPLAVVSCDNLPANGARTRDAVLGAAD--DPRLAQWITDHVSFVDTVVDRITPAATDDDRAA------SGDPCVVVTEPFTEWYLAGEFPAGRPAWEVEGARFVPDVEVYTRRKLWLLNAGHSLLAYLGLARGHTSIDEAMADGECRRALDALW-DDAAPVLPLPEREIRDARAALVRRFTNPRIRHLLEQIAKDGSAKLPARSTPVVAARLADGATpdGQLRLWSAWLAHLR-----SGWTSDADPGGAPLAARARtaDGAAAVVDHLL------------------------------------------
155 UniRef50_C8SYL4 Fructuronate reductase n=1 ... 320 7e-86 1 46.3% 1:257 4:261 IATATLPKNVQYPQYDRSQLRSRIVHFGFGAFHRAHQALLTDRVLNNVGGDWGICEISLFSGDTLMSQLREQDHLFTVLEKGADGNQPIVIGAVHECLNARLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGKLDPTHPRIIHDLENPTLPQSVPGILVEALARRRERGLPPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPALADWIADNVSFPGTMVDRIVPAATPESLAEIATVLGSTIPAPSVANpfSGW-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
156 UniRef50_A9WVA8 D-mannonate oxidoreductase ... 307 6e-82 1 30.4% 7:404 5:364 ------PTALSRSVLNLPAPAVRIVHLGLGAFHRAHQVWYTQHA--ADGAEWGITAFSMRSAAAADLL-AAQDGLFTLVERGAA-DSFELLWPILEVGDASADAGarMIELIAAPSTAVVTLTITEAGYVAGSVAVTLLRAGLAARA-----------------------AAGAGPIAVVPCDNLSGNGDLLASLIFPAGRA----------DGVSFISTSVDRITPRSTSADQERVLPATGREDAAPVVTEPYRSWILQGDFPAGRPRWEPAGAMFVADVTPWEQRKLWMLNGAHSYLANAGLVRGLETVAQAISDPELRAGVQALW-AEVAAHLPA-EVEAENYAAQLIERFENGRIEHRLSQIAADSVAKLRVRVPPVLRVEQMAGRSGAASRAVLEAWVR----------------------------------------------------------------------------------
157 UniRef50_UPI0001C347E9 mannitol-1-phosphate 5-dehy... 302 1e-80 1 18.2% 23:472 2:382 ----------------------KVIHFGAGNIGRGFIGKLLADANSQ---------VTFTDVNQPLIDQLAHQQSYNVHVVGQENRIEKV-----QHIHAVNSNDPKTIEFIATADM----LTT------------------------AVGPQVLEKIASTIAKGIIHRKSLGnqPLNIIACENMVRGTSQLKQHVL---AQLPEELHQWVEQHIGFVDSAVDRIVPPMDAAN----------DDPLDVTVESFSEWIVDQTQFVGDIPI-INGMELTDNLMAFVERKLFTLNTGHAMTAYLGQLYGYQTISESIGDLRIHTVVKSAMQESGQVLIQRYGFdhNQYIDKILSRFANPYLKDDVSRVGRQPMRKLsdRLIKPLLGTFEYQLPNENLIIGIAAALHFRCEA----------DPQANEMAKLIADKGIYQAVVEL---------CGLEQYPEVVDRICSQYQLLI--------------
158 UniRef50_A4IPF0 Mannitol-1-phosphate 5-dehy... 298 3e-79 1 23.0% 23:474 2:384 ----------------------RAVHFGAGNIGRGFIG----SLLAASGYD-----VVFVDVNEQIVRLLKERGEYRVIIAGERQEEQWVRG--VSALNSQTER-DDVIEAIASADL--VTTAV--------------------------GPHILPVIAPVIAAGLERRFTVHQKPLHVIACENMIGGTETLKQHVVTHLSEAGRQL---VEECVGFLNCAVDRIVPNQTND------------DPLAVTVEPFFEWAIETKNTIGAVP-PIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYQKQYRTVQEAMKDSGIRESVEQALRESGAVLVKKHGWDEQeyIETTIGRFTNPSLSDDIVRVARSPIRKLgdRLVAPAVQYYtfERVPSGLVKGIAALLLFDETGDAE----------ATALQQTIEQSGVEGALVQY---------AGLDNSHPLVVAVKEEYKKMQKE------------
159 UniRef50_A7FP92 Mannitol-1-phosphate 5-dehy... 296 1e-78 1 20.6% 23:474 2:384 ----------------------KALHFGAGNIGRGFIGKLLADAGAQ---------LTFADVNQPLLDALNKRKSYQVNVVGEQA-RVEEVKNVSAVNSGSPE----VVALIAEAD--IVTTAV--------------------------GPQILARIAATVAQGLITRHQQGnrPLNIIACENMVRGTSQLKQHVF---AALSEDEQIWVEQHVGFVDSAVDRIVP----------PSEAGSTDILAVTVETFSEWIVDGTQFKGQPP-EIVGMELTDNLMAFVERKLFTLNTGHAITAYLGQLAGHQTIRDAILDPAVRQTVKGAMEESGAVLIKRYAFDPqaYINKILSRFENPYLHDDVERVGRQPLRKlgDRLIKPLLGTLEYQLPHDSLVTGIAAAMSYRSE----------QDPQAQELVTLLAQLGPKAALAQI---------SGLPADSEVVEQAVSVYNAMQQK------------
160 UniRef50_D2R7C9 Mannitol dehydrogenase ross... 292 1e-77 1 19.6% 18:400 2:370 -----------------AELSETVLQLGAGRFLRAFCDRFIHQANASSRPVGKIVVVQSTAGSRADSLASRPEG-YSVLVRgePVERIDLVASISRALVAGTQ-WSEVQRLVQTDALKFVISNATEAGYKLADG-------------DAPSDAPPSSLPGKLAQLLHLRYAKDLAPLVMLPCELIESNGAKLRDLVVEQARRwgEAFIDYVTNKTQWVNSLVDCIVTSPEPTNPHLT------TDPNLVCAEPYQLWAQQPLDPSMPQPIDHPAIRWVSDLSPFYLRKVRILNGLHTAMVAKFFGTGPVTVADVLADLEKAKWLRALLFEEIVPTIAYRVSDVAEFADQTWDRFRNVHLNHQLKDIALNHAAKLQVRLAPTADEYQrfGCRPAKLDEALA--------------------------------------------------------------------------------------
161 UniRef50_B0K280 Mannitol-1-phosphate 5-dehy... 288 2e-76 1 22.0% 23:473 3:383 ----------------------KAVHFGAGNIGRGFIGYLL--------YKSGYE-ITFVDISKELVESINNYKRYNVIIL-KDNVEKEEVKNIKAI---HIEDEENLSKAIVDAD--IVTTSV--------------------------GANNLKSIGEKLINYLKIRKANIDKPLNIMACENALFATNILKNSILE---KGDRDFIEYVNQKIGFPNTAVDRIVPNVD----------IKKELPIDVAVEDFYEWDIEKKAIIG--DLNIRGAELVDDLEPYIERKLFLLNGAHATTAYLGYLKGYKYIHEAIEDDFIRNIVSR-MQEEASLALSRKhdDLERYASKVIKRFKNPYLKDEVVRVGREPTRKLSvrLMMPAKLCYEIGITPEFILYGIAAGFLFDYKEDPQACKIQ-DDIKNFGLEKTISKV------------------TGLEENSDLLQEIVKKYKELKE-------------
162 UniRef50_A7MWS7 Mannitol-1-phosphate 5-dehy... 287 7e-76 1 18.3% 24:471 4:382 -----------------------AVHFGAGNIGRGFIGKLLADAE---------VEVTFADVDAPLVDQLSHKQEYKVKVVGTE-CQIDTVTHVTAVNSASEDVIDRIVKT--------------------------------DLVTTAVGPNVLDIIAKTIATGIAKRFAAgdKPLNIIACENMVRGTTHLKGEVYKHL---DESLHSKADELVGFVDSAVDRIVPPAEAAN----------DDPLEVTVESFSEWIVDEQQFKGEIP-DIAGMEKTNNLMAFVERKLFTLNTGHCITAYLGCLKGHRTIREAIEDPSIHAEVKQAMQESGEVLIKRYGFdhNAYIEKILGRFANPYLVDEVDRVGRQPIRKLGarLVKPLLGTIEYGTENKTLLKGIAAALKYTN----------DTDPQAVEQQNSLKEVGVKKTLATY---------TGLAENSAEVTQIETLYNQL---------------
163 UniRef50_A1SR48 Mannitol-1-phosphate 5-dehy... 286 1e-75 1 19.6% 23:472 2:382 ----------------------KAIHFGAGNIGRGFIGKVLSDA--------GIK-VTFADVNKTVVNALIARNEYDVNVVGAD-CVVEKVTNVTAVNSAGSE----IVKLIAESDL--VTTAV--------------------------GPTVLNIIAKTIADAIELRLNSGNkpLNIIACENMVRGTSQLKAQVFKYL---PESLHVQSDQTIGFVDCAVDRIVP----------PAEAGETDPLAVTVETFSEWIVDQTQFKGEIP-TIKGMECTDNLMAFVERKLFTLNTGHLITAYLGVLAGYETIKESIEDEAIRSDVTAAMQESGEVLIRRYGFDPqaYIQKILGRFANPYLRDEVDRVGRQPIRKLSarLIKPLNGTLEYGLPNGHLIKGIAAAFLYKN----------DQDPQAVELQAMFAEKGLAATLAHY---------SGLAVDSETVKLVEQAYQSLK--------------
164 UniRef50_C9RTC9 Mannitol dehydrogenase doma... 286 2e-75 1 23.2% 23:474 2:384 ----------------------RAVHFGAGNIGRGFIG----SLLAASGYD-----VVFVDVNEQIVRLLKERGEYRVIVAGEQQEEQWVRG--VSALNSQTER-EAVIEAIADADL----------------------------VTTAVGPPILPAIAPVVAAGLQRRFAIQQKPLHVIACENMIAGTEALKTHVFEHLSADEQRLA---NQSVGFLNCAVDRIVPNQTND------------DPLAVTVEPFFEWAIEARNVIGAVP-PIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYLRNYETVQEAMNDEDIRWNVEQALSESGAVLVKKHGWDANeyIDTTIGRFMNPSLSDDIIRVARSPIRKLgdRLVAPATQYYafERVPFGLVKGIAALLRFDDASDA----------EAAALQQTLKQRGVEEA----------LWqaGLDRGHPLIAAVKEEYGRMEKN------------
165 UniRef50_Q8EN87 Mannitol-1-phosphate 5-dehy... 284 4e-75 1 19.7% 24:474 4:385 -----------------------AVHFGAGNIGRGFIGLLL--------YQSGYQTIFIDVNNQVIDEINKQK-SYHVYLAGKEKQELTviNSIKE--------PDAVTEAIVKAD----------------------------VVTTAVGPTILPVIAKAISKGLQERTKQNNSPLNIIACENMVGGSSLLKEHVFESLEAHK---IGEFDRLYGFPDAAVDRIVPNQTNKNL------------LDVMVEPYYEWVVEKKKIVGEVP-PIFGITYVDDLAPYIERKLFTVNTGHAIPAYLGTHLGYDTIVEAMKDLRIDDTIYGALAESGEALIHAYGFnhQEYVSKIIQRFQNPYISDDVKRVARGPIRKLGarLVKPALMYIEygKIPVYLAKTIAAALLFNNDEDRE----------AIELQKKISATGYQQAFVE-------VSGCD--SDSILTKKVIEQLRLLQNK------------
166 UniRef50_C9KJT2 Mannitol-1-phosphate 5-dehy... 284 5e-75 1 19.3% 24:417 12:354 -----------------------AIHFGAGNIGRGFIG----ELLVQSGYE-----VTFVDVNDELVKTINEKKAYNIKIVGDEPQTVHV--EHVKAINSNT-NLEDLLTAIVKAD--IITTAI--------------------------GPNILKFIAPNIAKGLERRVKVNETPLNVIACENMVGGSTVLKNFVYEHLSDEAKPL---VDKLIGFPDAAVDRIVP------------LQHNEEPLLVQVEPYCEWDVNRTQAKGEVP-EIKGLTWVDNLQAYIERKLFTVNTGHASIAYMAYQKGIKDIYSAMQDPEIVAFVRKVWGETGSMLIEKYGFDpqKYVETTEKRFANPHLSDEVTRVARGPKRKLGarLVSPATQLIEQGKTPSALAKVIAAALHFDYEGDKEAVEVQ---------------------------------------------------------------------
167 UniRef50_C2KB11 Mannitol-1-phosphate 5-dehy... 278 3e-73 1 17.5% 23:474 2:386 ----------------------RAVHFGAGNIGRGFIG----ETLADNGF-----GIDFVDVNETIIDELNKRGEYDIELAAPGKKRIHV--SNVDGINNAKD-PDKVVEAIKSTDM----------------------------ITTAIGPKILAIIAPLIAKGLTARIQSGntPLDVIACENMIGGSEHLKEEVYKHL---DDDVKPELDKYIGFPNAAVDRIVPIQHND------------DPLFVSVEDFKEWVIDESQMKNK-DIKLKGVDYAPDLEPYIERKLFSVNTGHATVAYTGKSLGYDTIGDAIKDPFVLKQVKRVLSETRSLLYHktEESLEEYHNKILSRFQNPYISDDIARVGRTPIRKLgeRFIRPIRELKDRGLDYSALMETVGRIYHFD----------EPNDKESVKLMQMLKDEDLKDVIVET---------TDLKDDPELVDEIVKSYHDAEAD------------
168 UniRef50_C4L274 Mannitol-1-phosphate 5-dehy... 276 2e-72 1 21.9% 23:419 2:340 ----------------------KAVHFGAGNIGRGFIGLLLNQ--------SGYE-VTFVDINDTVIEALEVKRHYEVG-FAEDGVDRIVVDRVRGV--NSLKEPARVVDLIAEADL--VTTAV--------------------------GPSLLSKVAPLISEGLRAR-EVEDAPVYVIACENMIGGSAILRQEVEACGGVG--------EANVFFPNAAVDRIVP------------LQQHEDPLYVEVETFHEWVIETQGLNEQPP--IQGVTWVEEIGPYIERKLFTVNTGHAIASYIGSLFGKATIDEALKDRRVRQVVQGALYETGWLLLEKYGFEAKeyIQKIIKRFENPKLKDEVSRVARSPIRKLgdRLVKPARELMDNGIEPNELAYGIAAALHYYNPEDSESSELNLS-------------------------------------------------------------------
169 UniRef50_A6WFS7 Mannitol dehydrogenase ross... 274 8e-72 1 28.4% 16:416 26:387 ---------------DRGLRTPAVVHLGVGGLRLAHHAVCLHEVVRRRLSdwGLVHVELRPpdGLIRLDRERDHR--VQLPGTSSPEFREVEVLTE-FTTSADDSAAVLDVLADPATRLVTLRVSE---------------EQEFFGLCAAPEHprIAHGYLVRALARRRDAGLPPFTVLSCDPVPRNGARTRDAVLELARRTDPLLADWIGRDVRFPGSLVDPTLPGGS--------------------ALPFR-WVVEDDFGHGRPPLEEAGAHLVTHTAPHEQLRMHLLDGARCALGLVGGTAGARTTAEALADPRVRAFLGGFLEEAASSLLHVPGVDLPGYRAAVLARLAG-----ADEPLPRSGSAAVSAVVLPSLRQALDHYRPRRHLVLAVAVWLLTLPGSGGDARTM----------------------------------------------------------------------
170 UniRef50_Q1QWS2 Mannitol dehydrogenase-like... 272 3e-71 1 20.2% 17:402 4:371 ----------------PTLAEAGIVQFGTSRFLLGHVAAFVHASREAGHTRDGILVVQTSPREAGKQKARDLdrQYPLAIRGrdIDTRETVTSIAGCWIAD-EQWDALERHIVEHA-RFVVSNTGDSGYRVDD--------------DSALAAVPTSFPGKLAKLLHARYRAGREGLTVLPCELVSRNGEQLLALVRELAQraDADFDNWLTTRCLWANTLVDRIVSAALE--------------PVGAVAEPYALWAIED-QPGLELPCRHPDVQRVTSLAPYEMRKLHILNLAHTYLVHRWQrsHIRFVREAMDDPAWAAELRQVLDDEVLPTLalERPSLEAYRDATLERFANPYLDHALQDIAQHHATKCQRRLQPVVESARRRGIATPRLDDAISSA------------------------------------------------------------------------------------
171 UniRef50_Q2B9X7 Mannitol-1-phosphate 5-dehy... 270 7e-71 1 21.5% 23:417 6:346 ----------------------KAVHFGAGNIGRGFIGALFSK--------SGYH-VTFVDIAEEIINLLNEQGEYKVNLAAENGSSEKI--SSVSGLNNMTQESQ-------------VIEAIGEAEY----------------LTTAIGPNILPRIAPLIAKGIAERVKKTDDKLYIIACENQISATDLLKGYILE---NLDEETAGKLEGRVFFFNSAVDRIVP---------IQNNQGSLD---VLVEPYYEWVVE--APTDIPAVE--GMKIVPDLAPFIERKLFTVNTGHAVIAYLGYLAGKETIDEALKDEAVYKQAEATLKETGAYLVKEYGLDAEeyIKKIIGRFQNGFLNDGVTRVGRSPIRKLgdRLVRPAEQAMKAGLPFENLAKAIAAALHFDFQGDEEAVKIQ---------------------------------------------------------------------
172 UniRef50_Q5WDV0 Mannitol-1-phosphate 5-dehy... 266 1e-69 1 18.7% 23:466 2:373 ----------------------KAVHFGAGNIGRGFIGALL--------VDAGYE-VTFVDVNEKIIDALNERNEYKVTVAGERKETETVTN--VRGINSKTNEKEAIDAIAE-----------------------------ADIVTTAVGPTVLPYIAKTIAQGLKQRTAS--KPVNMIACENAIRATSQLKKDVLSHLS---EEETTALLKDAGFADAAVDRIVPNVQSD------------DILHVTVEPFFEWVVEKPALKG-DAVQLGKAVLVEDLAPYIERKLFTVNTGHAVAAYVGYRKGKKTIKEALADDYIKHRVRGALNETKAMLVEEYQFDAEayIDKILLRFQNPHLEDLVERVGRGPIRKLgdRLVKPAKYLAEKGLHPESLAETIFDALHFYAEG----------DPESEELRALVDEKG----YVDAFCEISK-----LEKDHPLVEIVAK--------------------
173 UniRef50_UPI0001C42D08 mannitol-1-phosphate 5-dehy... 266 2e-69 1 18.8% 24:470 3:378 -----------------------AVHFGAGNIGRGFIGEVLHKN--------GYDIYFVDVAQPLIDQLNEQKSYY--IRLAQEKEETVLIKNVY-GLNSQTQA-DEVIDTLAKADLITVS-----AGVNILPL-----------------------IAPILAKGLLKRVEAGAGAVDVIACENAIGASTTLKGHVLD--EMKDNKAKEAILANVGFPDAAVDRIVPNQTR-------------DGLNVLVEPFFEWVVAAKGMKTGERLQ--GVNYVEELNPYIERKLYTVNTGHACLAYVGFAKGIPSIAEAVADQSIRKELEEVLKETSRLlyQFDGAELKEYREKIISRFENVHLSDPVERVGRNPLRKLSarLIGPLVQLYDRGIQSPHLVKVAAAAFQFDVPSDEESVKI----------QSMLKEKGLEETITKV---------TSLSADHPLVTQIKEQLEA----------------
174 UniRef50_C4V0J5 Mannitol-1-phosphate 5-dehy... 265 2e-69 1 20.1% 24:417 6:348 -----------------------AIHFGGGNIGRGFIGELL--------VRSGYEVTFVDVADALVDEINARR-SYDIEVVGDTPKKIHV--EHVKAINSNKD-LEALLDAFVTAD--IVTTAI--------------------------GPNILKFIAPNIAKGIARRLEKTDAPLNIIACENMVGGSTVLKNFVYEHLA---DDIKEKAAHCIGFPDAAVDRIVP------------IQHNEDPLLVKVEPFCEWDVDRTGVVGAEP-QIEGLTWVDNLEAYIERKLFSVNTGHASIAYMAYLKGIEDIASAMQDEEIVAFVRRVWAETSELLIEKYGFdhAEYIRTAESRFKNPHLSDAVTRVARGPKRKLGarLVSPANQLVARGKKPEALATVIAAALHFDYAEDPEAVEVQ---------------------------------------------------------------------
175 UniRef50_Q0CXS6 Mannitol-1-phosphate 5-dehy... 265 3e-69 1 15.7% 23:474 4:386 ----------------------KAIQFGGGNIGRGFVAEFLHEA--------GYEVVFVDVMDAVVSALQTTP-SYNVTEVSKDGENTKTISNY-RAINSKTNESDAVKEIAT-----------------------------ADVVTCAVGPNILKFIAPLIAKGIDARTES--KPVAVIACENAIGATDTLHGFIKEH---TPKDRLDTLYDRARFANSAIDRIVPNQPPNS------------GLNVRIEKFYEWAVEQTPFGSFGHPDIPAIHWVDNLEPYIERKLFTVNTGHATTAYYGHLRGKKMIADALADDEIRSMVHKVLDETASLIVSkpEDEQKEYVDTIIGRMSNPYLEDNIERVGRAPLRKLSrrFIGPASQLAERGQKFDALVDAIEMALRFQN---------VPGDQESADLAQILKQKSSEDATSEL---------TGLEKDHPLYSPVLERVAKVQQD------------
176 UniRef50_C0Z8I6 Mannitol-1-phosphate 5-dehy... 262 3e-68 1 21.6% 24:417 3:344 -----------------------AVHFGAGNIGRGFIGQLLQKA--------GYEIAFVDVNAALVDELNERK-MYRVQLATTGKPESVVEG--VRAINGQ------------------------------DVAAVAEAIATADLVTTAVGPNILPHIAGAIAAGITQRLTVHARPLNVIACENMIGGSEKLKEHVYEHleSVQAQAAQWI----GFPNAAVDRIVP------------LQQHADKLLVMVEPFFEWVVDSSQIVGEVP-AIEGVTYVEDLAPYIERKLFTVNTGHAVIAYLGYQLGMKTIDEAMRDDRIVQATRGALQETGALLAAKYGFDPqqYVEKILGRYTNPLLSDDIVRVARSPIRKLSqrLVGPALQCMEKGMNASYLGLAIAAALAFDYPEDAESARIQ---------------------------------------------------------------------
177 UniRef50_A2RH97 Mannitol-1-phosphate 5-dehy... 257 7e-67 1 18.3% 23:449 3:379 ----------------------KAVHFGAGNIGRGFIG----EILSKNGFE-----IYFVDTNKAIIDELNTRHSY---EIGIASSSPEKI-SVSGVFGINneNPKDVIEAIAQAD--IVTTAI--------------------------GPNILPYIAELVAKGIQKRKEENKqqIDIIACENMIGGSEFLEKKVAEYLSDSD---KVYLANYIGFPNAAVDRIVPGQKH------------EDLLYVEVEPFCEWVIDESQIKNK-SFKLEGVHYASNLEPFIERKLFSVNSGHATVAYSSAYKGYKTILEGLQHKEILSALKGVQKETRALLLAktEEDLMSYHQMIISRFANPKIIDEVTRVARTPIRKLgeRFIRPIRELNERGLSYQNHLDIVGKIFAYQDENDSQS--VQLQEKLSTMDFQRLIEEVTGLSNKKIILEIELV-------------------------------------
178 UniRef50_D1APL6 Mannitol-1-phosphate 5-dehy... 255 2e-66 1 18.1% 23:474 3:384 ----------------------KAVHFGAGSIGRGFIGDLLH--------DTGYEIV-LVDVDKNIVEQINKTNSYDLYII-EENYKKKTIDNVKAVLLTDTDKIAGEIAGAE-----LVTVSV-------------------------WVDNLPGVAVPLLA-GLKKRVGKEAGKLDVLTCENAIHNGSILKNEVLKL----DADFTEdlDKAAAFPDTAVDRMVLASERNGVKSVDIGLA------------HELVIEKSKLTDPESEPVKGAVYTENMDKYIERKLFIINGGHAWAGYMGHICGFTTMQEVFEDENFTSSVREVMQEIGALIAQKYNfeLNNYIDFVINRFKTPGITDYISRVSRNPIRKlgERLTGPCIQCEERGLKNDRLIEGIAAALLYDISEDKQSS----------ELQTHIKEHG-IEESVS--------FYTSIPADSKLHKKIVENYKILSEK------------
179 UniRef50_B0MBD0 Putative uncharacterized pr... 251 4e-65 1 20.1% 23:416 17:359 ----------------------KAVHFGAGKIGRGFIADLLH--------DTGYEIVFVDVNEKVNEELNKYHNYYLYVI--EEDYRRKEIDKVS-ALSPITEE-DKVVEAIVEADV------VTTA-----------------VLAD-----NFPKIAGTLAKGLKARLEAGKERVNVIPCENALFNGDLLLKELVKTEIASEDDFL----KAAAFPNTAVDRMVFGTDKDGRDGID------------IGKDHELAVEVNKLVDPEKLPIAGAEYTDNLQKFLERKLYTINCGHAWSGYIGKLMGYEIIQDYFAVPENIEMTREVMREVAALMVAKHGfeMEDYITFALNRFCTPGIKDTITRISRAPIRKlnDRLVGPAVQCEERGLKNTLLLRGIAATFLFDVKEDEQSVEM----------------------------------------------------------------------
180 UniRef50_A6LQT9 Mannitol dehydrogenase, C-t... 249 2e-64 1 18.7% 23:417 2:346 ----------------------RALHFGAGNIGKGFIGY----LLNKAGFD-----VCFVDVNQSAIDKINRNKRYLVELLDDD-HTVEVISPVS-ALNSITQ-KEEVLNSIVKADII-----TTSVGIGNIPR-----------------------IAECIAKGLLKRIKINKTKINIIANENAINASSTLKKEVEKYLSNEE---INKICEYVGFPNSAIDRLALSKENE-----------EDEVALV-EPIYEWVINESEMVNNNLPYIKGVTYVANLTPYIERKLYCVNMAHAATAYLGFLNGEKTIQDTLKSHVIESIVKGALNETAQYFIKEYDISLEefMEKILLRFKNKNISDDILRVGRSPVRKLgeRLVGPTLKLYEKEYPVKYMAMLVAGALLFDNPEDEESVILQ---------------------------------------------------------------------
181 UniRef50_B8D8D5 Mannitol-1-phosphate 5-dehy... 247 1e-63 1 15.7% 23:416 2:344 ----------------------KALQFGAGNIGRGFIG----KTLSESGFS-----VIFSDVNQNIVDAINYNREYFVKIIGSNQNKTVNIKRVS--------------------------------AINSNDSNIKKIISSVDLITTAVGPTALEKIALIITQGIIFKIKNqtKPLNIIACENKIKSSSFLKQVVLK---NLPIKYHDYLNKYIGFIDCSIDTIIPS------------INNKDDLFLTVEEFKEWIVNINQFKGAV-LKIVDMKFSNNLDAFIERKLFTLNTGHAIAAYLGLIKNYKTIQDAISDKKIRVIVRSAMEESGSVLIKRYNfdHLDYIEKIFLRFENPFLSDKLERIGRNPLQKLRrrLIKPFLGAFEYNLPYSNLAKGIAAAFYYHNKNDLESIEL----------------------------------------------------------------------
182 UniRef50_C9B6N7 Mannitol dehydrogenase n=1 ... 245 2e-63 1 15.7% 23:442 2:373 ----------------------KAVHFGAGNIGRGLIGQILHQ----NGFD-----LCFIDTNPELIHQLNQDKGYTI----------EIIDEMNR-----SDFIDHVVALNSLSELEEVITAT----------------KNADILTTSVGAINLVKIAPIIAQALSKRFEQKHS-INIVANENVINASDVLKKEIYSLLSEKEQEN---FDEYAYFVNTAIDR----------QSLGKVLGGKMISVV--EPYYEWIMDRQQLDPTTSFDLKNVNLVDDMEPYIERKLYIVNAAHAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHfeLTSFVEKTLNRHGNQKLSDEITRVGSSPIRKLgdRLIAPIVKLDSYHLPYDAGIKVIAAGYHYRNLADPEAEQLrvNDGLKATIKKISRLEGKLLNEVVA--------------------------------------------
183 UniRef50_D1AQI8 Mannitol-1-phosphate 5-dehy... 245 2e-63 1 19.3% 24:417 3:346 -----------------------VFHFGAGSIGRGFIGKI----LSENSYN-----VTFIDVNEEIISQLNKDNEYTVETVGA-NSKTETVKNVCGLLSGDLEGIKRKV-----PETDLITTAV--------------------------GANVLEIIAPTVAEIIKFRKNSGITriNIIACENKLEASTFLKSKVEKYL---DENEKEYMETYAGFVNSAVDRLIP--PRKIEGKEATYTIVED--------FNEWIADETLIKGELTLK--GMIKKKDLTPYIERKLFTVNTGHIIAAHMGVYMNYETIDQAVCDEKIRKIIIGAMEESGAVLIKRYGFDKEeyIQKILKRFENKYLGDSTVRVGREPLRKLGvrLIRPLLGTLEYGLPNENLLTGISYALKYDVPSDRESVELQ---------------------------------------------------------------------
184 UniRef50_B1KB28 Mannitol dehydrogenase doma... 244 4e-63 1 21.2% 20:382 1:352 -------------------MTPPILQFGTSRFLLAHVDLFVSQALDDGNAMGGIGIVQTTGNParIDALRAT-GRYPVRIRGRevDEVVECRAVQRAWDAERDWAE--IRAAAIETVRVIVSNTGDAGYRPDPRDAVDLLAQP--------AHAPHGFPAKLLALLHARWqrPDDGVSILPCELVTNNGDTLRDIVLGLARQwpDAFTDYLSSRCVWVNSLVDRIVSEPLH--------------PVGAIAEPYALWAIERR-AGTALPCTHAQIVVTDDLRSHERLKLFFLNLGHSWLAEQWLAAGreTVLDAMNDARLRDGLEAVWRDEVTPVFVALGltAERYVESVRERFLNPFLAHRIADIAVNHREKVARRIEPLL--------------------------------------------------------------------------------------------------------
185 UniRef50_C8WQV8 Mannitol dehydrogenase doma... 242 2e-62 1 20.0% 23:417 3:345 ----------------------RALHFGAGNIGRGFIGWLLAEAGFQ---------VTFADVVPGLVNELAAKRSYRVIELGEEKRVVEV-----QGVDACLLGSERCIELAATSD--WITTAV--------------------------GVRHLEGVAAVLVEGFRRRMQAGREgvIVIACENAVRATSQLRHHVERLA---DDALREFLDACVRFLDAAVDRIAPN----------REGHAEDALDAVVESYYEWVVEASPVPGAPH----GISWVSDLDPYLERKLYLVNGAHAAIAYLAHLRGITTIGEALSRKDIEEHAARFQEEaaHRHAAFDVADLAAYAEKVRTRFANPYVVDHVARVARDPLRKlgERLVGPLVAAAEAGSETTAIERAIASALYYVDENDEASVELQ---------------------------------------------------------------------
186 UniRef50_A7IBN9 Mannitol dehydrogenase doma... 241 5e-62 1 21.2% 23:400 4:370 ----------------------RIIQFGTSRFLQAHVDLFVHEARQAGQAVGPICIVQASGAADRAGRVAAFggGYPVIIRGIEkiERRivTSVDRGLSAA-QDWQALSDLFAKDA-DIIVSNTADAGYEIAAADRGPA---------LLAGGVPVSFPGKLTALLHRRWRQSGRGLTVLPCELINRNGRVLSAAVAALAPeaPEAFLAWLEAEVIFADTLVDRIVSQALE--------------PIGAVAEPYALWVIERR-PGLDLPFTHPSVVLADDLEPFERLKLHILNLGHTVLADIWRSERreTVREILADADVRGRLDDVYRHEVLPGFAAHGmeAQRYVATTLERFLNPFLDHRIADIAQNHATKVDRRITAFLSWWAEAggATPTLDVVIA--------------------------------------------------------------------------------------
187 UniRef50_D1AJ18 Mannitol-1-phosphate 5-dehy... 237 1e-60 1 17.7% 24:413 4:340 -----------------------AVHFGAGNIGKGFIGDLLHD---SGFY------ITFVEVNDAVVQSINRTNSYDIYVID-KNYEKRTINNVS-ALSSGEEE-------------------ITEA------------ILDADMVTTSVWADNLAKVAPVIAKGLQKRIDNKKEKLNILACENALYATDILKKEILKNLKADESEL----NNYACFPNVSVDRLALNIIKDG------------EPAVEIDSSFELVIEKNKLVNPDTEPIKGAIYAENLTMYLERKLYIVNCGHAAAAYLGFLKGYKIVQDALKDKEILEEVLGAMNESAAVLQKKFGfdLQKFIQKNIKRFTSEAVKDDILRVGRSPIRKltDRLVAPALGCIEYNYETKYLSKIIAAVFHYENPNDEQA-------------------------------------------------------------------------
188 UniRef50_Q6AHH7 Mannitol-1-phosphate 5-dehy... 236 1e-60 1 20.0% 23:417 2:346 ----------------------KAVHFGAGNIGRGFVGLLLHEA--------GYEVV-FADVNAELIEALAAADSYDVRLVGDETVTKTVTG--FRALNSATAEDELVGEIAT-----------------------------ADVVTTAVGPRILRFVAPVIARGLGAR-ASGAPRLVVMACENAIGATDLLAAELMDGLQ--DGDTRDELAARAVFANTAVDRIVPAQDPAS------------GVDVTVEAFFEWVVDrpFAGAEPP--IPGAHFVDSLGPYIERKLFTVNTGHATTAYTGFLEGAATISEAIAKPSVLATVEAVLEETSAALTAKHGLdlAEYRAKILNRFRNPHLVDEVTRVGREPLRKLGrrFIGPASDYARygGAPSALLAAVGAALRFDLPGDSQSAELQ---------------------------------------------------------------------
189 UniRef50_Q2VSS2 Mannitol-1-phosphate dehydr... 235 3e-60 1 21.2% 55:403 8:340 ------------------------------------------------------IFVTFADINQTQIDQINQNKQYGVKIVGDD-SRVEIVKNIA-AINSKDEN--AVIEQVKNTDL----------------------------ITTAVGPNVLGFIAPLFAKALVARVESGNtpLNIIACENMVRGTTFFKGKIFEHLTA---EQQAEIEKVVGFVDSAVDRIVP--PAEQQAEIEKVVGfaDPLEVTVEEFSEWIVDQTQFKGDIP-NIKGMELTDNLMAFVERKLFTLNTGHLICAYLGKQAGVKWIKEAIAIEEIKTQVKATMEESGAVLIKRYGFDPqaYIEKILKRFANPYLNDDVNRVGREPIRKLSerLIKPLRGTLEYGLPYQNLVKGVVMAL-----------------------------------------------------------------------------------
190 UniRef50_B3W862 Mannitol-1-phosphate 5-dehy... 232 2e-59 1 16.3% 18:460 2:385 -----------------KTMKKSAVHFGSGSIGRGFIGKLLH--------DSGYQVTMLDVDDSIISSINAIGglYLINHNYQKVFIDQV-----SAINSLKDTQGA-IDAIKDAD----------------------------IITTAVLATNLEKIAPILSKGLKARLQLRKAKINILACENLENNSGVLRKKVLALGEIKENDL----ESIAAFPDTEVDRLVLKSERNGEPAID----IGDE--------FELVVDKTKLVNPGVEPIKNAFYTTDIHKYFERKLFIINTGHCWAGYVGHVYGYKVIQDVFANKPLLRATREAMKESAVLIEKKYGfdLDDYISFALNRFMTPGVVDQIARVSRNPIQKIgeRLVQPVQQLADRNLPYQQLVKGISAALLFDLDTDQQ----------AIELQHYIEKNGVKQTIVhgIAEESVLFSQIMEHYNRF--------------------------
191 UniRef50_Q89A37 Mannitol-1-phosphate 5-dehy... 231 4e-59 1 16.0% 24:416 3:349 -----------------------ALHFGAGNIGRGFIGP----LLLKSGFN-----LTFVDNNQAIVDAINRHQKYDITVVG---NNFSYITTVKKVKAIYINDPNIYFKIAK---INVITISVGVHAI-----------------------NSLVVFFEKLIR--YKIETNDFVFLTIIACENVFRCASKLKENIKILLPGI---YHKYLDKNISFVDSVVDKIVCPNDKNNSDDI--------NLSVKVEKFSEWIVdtQFKHDRP--NIIGMIYSNHLDAFFERKLFTLNTGHAIAAYLGLLIGYKNIYQAILDPLIFNIVYGAMKESGMVLIRKYNfeHKNYILKILSRFKNIYLTDSLKRVGRNPLQKLKkrLISPLIDTIKYNLPNANLMKGIAAALCYIDEKDIEAKKL----------------------------------------------------------------------
192 UniRef50_C9CRE2 Fructuronate reductase n=1 ... 231 5e-59 1 39.0% 251:486 190:415 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CEPFRQWVIEDDFANGRPPFAEGGATLVTDVQPFEEMKLRLLNGAHTTLAWLGQLLGYQTVADCMADKELRALVRHLMLAEQAATlpLEGIDLAAYADELLKRFENTRLRHRLDQIASDSSQKMPQRLFAPIAANFEVKRDWSVSAVAVAAWIMGLR------SLPPVPDPRQDDLRRAALS----DDPVAGVLSLPSLVPDALRARAEFQTAISAAFDRL-QGGAKSAVTTTAKE
193 UniRef50_Q6GER8 Mannitol-1-phosphate 5-dehy... 230 7e-59 1 17.2% 23:412 2:329 ----------------------KAVHFGAGNIGRGFIGYILADNN---------VKVTFADVNEEIINALATGHQYDVILADESKTTTRvvAAI-NSMQPSEELKQAILE------------------------------------ADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLG--------NNIHFANSAVDRIVP------------LQKNENILDVMVEPFYEWVVEKDAWYGP---ELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDfeQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIgdRIIKPLAYLYNKDLERTGLLNTAALLLKYDDTADQE--------------------------------------------------------------------------
194 UniRef50_B6W7M3 Putative uncharacterized pr... 230 1e-58 1 16.5% 24:472 4:385 -----------------------AIQFGAGAIGRGLLGKIIH--------DSGYELVFVDVFDKIVDQINE-DGYVGLELMDHDNEAIKL-DKVSALCSTKTEDLEKIYEKIAQAD--IITTSV--------------------------RVENLDSTSKILVKGLEK-KEANSPKVDIMAFENAFRASDILKNHILENSNFKEEDL----DKLATFPNTVTDRIVQNKMVDGRS------------VVEISDDFEAVIEQTKLKDPKSKPIKDAEYTQNIDEELERKLFLVNGVHAATSYFGHHKGYTMMDEAFGDEEILSDVKKLMEESSEVLIKKYGFdlDKFKEAKLNRFLKTASHDEVARVARDPQRKLGkrLVSPAISAYDNNSSYDYLAKAIAYAFKYDNKEDEK----------AMEIQEYIKENGIEKAI-------EKYTEITKKQRPGLFEKILDQYKKID--------------
195 UniRef50_B3W722 Mannitol dehydrogenase-like... 229 2e-58 1 19.7% 22:417 2:347 ---------------------ATAVHFGAGKIGLGFIGDLLHQ--------SGYHIVFADVVEKTVAQLRKEK-QYRLFLIDHDYQE-RIIDNVDAV--SSIQDPTGVVEAIT----------------------------HADIVTTSVMASNLPKVAPLIAKGLKARLEKHLPKMTVMACENAIMGTDILKKAMLDSGEMTSEQL----EQAAVYPNTAVDRVVFDGHHQGQDGIE----VGDA--------YELAIEREKLLDPNSEPIKGAEYVDNLEMYLQRKIYIINCGHAISAYLGQVHGYHTVQEVLHNERLLYQVKAAMAESAAALEAKYHfsLQDYIETmvKRMTTPGLSDPVTRVGREPIRKLsdRIIGPANECESFGLDNQYLLRGAACALLFHNPDDEQAVEIQ---------------------------------------------------------------------
196 UniRef50_B9CU65 Mannitol-1-phosphate 5-dehy... 223 1e-56 1 17.9% 23:412 2:329 ----------------------KAVHFGAGNIGRGFIGYILADNNIK---------VTFADVNEDIINALDSEHQYDVILADEAKTTTRvvDAINSA-KPSDQLKEAILE------------------------------------ADLITTAVGVNILPIIAKSFAPYLKEKKNHVNIVACENAIMATDTLKKAILDITGP--------LADYIHFANSAVDRIVP------------LQKNENILDVMVEPFFEWVIEKDAWYGE---ELEHIKYVDDLTPYIERKLLTVNTGHAFLAYAGHFENKATILDSIEDKQIEAGLRQALSETSQYITDQFDfeQKQYVEKIIDRFNNPNLSDEVTRVGRGTIRKIgdRIIKPLTYLYNKGLEREGLVKAAALLLAYDDNADQE--------------------------------------------------------------------------
197 UniRef50_B9DTG2 Putative mannitol-1-phospha... 219 2e-55 1 15.3% 23:474 2:380 ----------------------KAVHFGAGNIGRGFIGNILH--------DSGYELL-FVDMDKNLVQQIHNDREYEIQILDFD-QDPIIIDNVDAILG-----------------------NSTELVI--------EELVKADIITTSVGANNLKYLAQNMKNALLKRAELKTT-VTVIANENTINATDILSEEIFNICSEAE---RDKILSITNFVNSAIDR----------QAMSKNYNGKSVALV--EKYFEWVIEKNDYTKEIEGIIASAKFVEDLEPYIERKLFLVNAEHAAFAYLGKLFGYKTVQSSADNKDILNLVKRMTIENSRYfyNMDPVELESFISKTLLRHTNPKFSDEVERVGRNPIRKLgdRLISPFVKLTELSLPNICLTKVIAAALFFTDESDSESLQ----------LQAMIAKEG-VETVLEKICGLSEV----------LITQIMKEYNSIKSD------------
198 UniRef50_B0P2D9 Putative uncharacterized pr... 214 6e-54 1 17.6% 23:426 2:365 ----------------------KAVMYGAGSIGRGFIGALFSEI--------GYEVV-FIDVNDDVIHLINKEKTYPQIIMNEE-QPVHWIKNIRAV---DGKDPEAVSNEIADAD----------------------------IMATALGAAVLEKVAPVIAQGLLKRWEKESSnlDILICENLMDADILLRDYLLK---ALPEDKHALFEKNVGLVETSIGRMVPPADPDLIPEDEH------PLAVRVEPYDFLPVDKAAFKGMIPEYKKIIPY-EPFHYYLERKLYVHNMAHVTTAFLGQYLNKTYIHEAAHDIYIQSIVRGCMTESCMMlyQVPFSKLNAHMNDLLHRFKNSYLKDTVTRVARDPMRKLqdRLIGAARSCESLHITPVYLSFAIALALSFMEGEdeTVCKIKKEEPIAERI------------------------------------------------------------
199 UniRef50_A3PGB6 Mannitol dehydrogenase, C-t... 207 8e-52 1 22.2% 18:395 2:357 -----------------SDIRTPVLQFGTSRFLQAHADLFFSEAAEPRAVTVVQSSGDPARAARLGALAAPEG--FPVVIRgvASETETRVTSVKRTLSTATD-WSALTAIFCS-EVELVISNTGDAGYQPGPADFDADFSQEM------------SFPAKLFQLLAARFAAGARPLTIMPMELVPENGRVLRDRLLAIgnRAPAALMDWI-AGLPFANSLVDRIVSEPLE--------------PAGAVAEPYALWAIE-RAPRIAAPCAHPAVQLVDDLEEIERLKLHVLNLGHTSLVDFWKRRgdALVRELMDGPEGRALLE-LYETEVLPGfkGRGDEARAYLEVTLDRFRNPFLDHRIADIAQNHPQKAERRIGAFLDWVGRSGPDMPDL-------------------------------------------------------------------------------------------
200 UniRef50_Q1H0J0 HAD-superfamily hydrolase s... 199 2e-49 1 17.1% 48:473 241:708 -----------------------------------------------NNMRAGIHGFGAMGGGYLAQIFSHWDG-YTRPYEIIGASNNAILRSLVNAFGKYDVHYGNLAFHQTIDRIRLIDMA--------DEAAVCEMYAVSEIIGLCLPESAIKQQAAMIAKGLVARYQNGAGPLTILVILNKLSGAAFVRRQVKemVRMLDEQRAEQIMAMAYFTETVVNRMVSKIPKEIlkHTQKALGSGeePALLAEPGLGKIVSQLRHASHlaLDQLGVTlvDNIAEIQAIKNRLLNGTHAIIAWYASLLGYQTIGQGMGDERVVMLVKRLVNNEIKPAMLQENPALAEYINTS---FVNSFikDPCRRIGRDPLRKLQrrIMGSIELAARHGIQTPMLEFGAALGILY------SLRLITPEDKECQRIKALFEENGAVAD-VLAFSGdkPYLGLDRQQDAALIERIAEHLRQLTD-------------
201 UniRef50_A8EUM4 HAD-superfamily hydrolase n... 192 3e-47 1 17.5% 50:473 243:660 -------------------------------------------------FKAGIHGFGAIGGGYLSQIFLHWDG-YTRPEKITGASKNVLLRDLINSSGKYTIKYESIAYHQTIRGINIIDLNDREA--------IDKMYIESDIIALTLPESAIKTQAINIALGLKARYKKHDKKLTILIVMNKIGAKKYVKRHILKSLKTieDKEATQIINNTHFCETVVNRMVSNIpsNALKQFKENLSEIDELNisSEPDILIYAD----NNSPILNTlqVKTVSNIDIMQNIKNKLSNGTHAIIAWYSSLLGYKTIGQGIGDKRVYSLAKRIMENEIKPFLINETPELKSY---ILE-FINNFikDSCHRVGRDPLRKLQkrVLGNIFSAQNMDLKTQNLEFGVACAILYSLLVA------PSKDKEATKIKELYAKRNKVEDIldGEYNFKPYKGLDKKIDAKLIKRIENKLEKIKT-------------
202 UniRef50_B0KG55 HAD-superfamily hydrolase, ... 191 6e-47 1 16.1% 48:483 242:710 -----------------------------------------------NQFRVGIHGFGAIGGGYLTQVFSHWDG-YTRPCEIIAATRSRMLRESVNAFGRYSVRYGATSFDQTIDNVRMIDL--------DDDDAVIGMYTTAEIIGLSLPEQAIRNQAKVIAKGLLQRFERRGRELTLLIVLNKVGGAAFVRRHvaELALLCPPAIGKQVLEKTHFAETVVSRIVSKLSNDALVRQLrqNSLEDEPAVAtePDMPLYVE----HGSDLLERlqVKTVPDIAQIQVIKNRLWNGPHAIVAWYASLLGHDSVGQGMGDARVCELAERLIRQEVGPAL------VAEymAEVVSRFADTFlkDPCARVGRDPLRKLQrrILSSIDLARKQGIETPALAFGAALAIHH---------ALRCKDDKALEAQAIRQVYRDNGASVEAVLThkRFPGLDPITDAQLISAISDAFRQYPQRDVANRLDDL---
203 UniRef50_UPI0001B478FE Mannitol dehydrogenase doma... 188 5e-46 1 36.2% 6:182 18:195 -----LPSSVKVPAYDRSRITTGIAHLGIGAFHRAHQAAYTDAVLTSGSNEWGIVGVSLRRPDTR-DALQIQDELYTLAIRDGDSEKLQVIGSIQNIL-VAPEDPQAVLDIMSHPDTRIVSLTITEKGYCRDAAVSGLDRSHPDIIYDLAHpaRPSASSQKHSGGGAPRERRRLPFFPVIIC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
204 UniRef50_C9V541 D-mannonate oxidoreductase ... 181 7e-44 1 40.7% 309:485 2:179 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTVSQTMAAPGFKQLIKALMEIEIAPTLplEGFDLSSYQAALIHRFENHALHHLTSQIAMDGSQKLPQRLLNTIQERLDGGGSIDRLALGVAAWMRYVTGKDEAGTPIDVRDPLSGQLLDQTQGKFAPDEIMDALLSFRQIFTARLAANELFREKLRLALGSLYAVGSAETVRRYAE-
205 UniRef50_UPI000190FD9C D-mannonate oxidoreductase ... 180 1e-43 1 46.5% 4:160 6:164 ---ATAQVSVARPNWDKSRLVSRIVHLGCGAFHRAHQALFTHHLLEKSDSDWGICEVNLMPGNdlIANLKAQNLLYTVAERGAESTELKIIGSMKEALHPEFDGHAGILAAMARPETAIVSLTVTEKGYCTDPASGELDVNNPLIQNDLAHPQQPKSAIG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
206 UniRef50_A8RA68 Putative uncharacterized pr... 179 2e-43 1 14.4% 27:478 7:390 --------------------------FGAGKIARGFLG----QLLYLSDFE-----ITFVDVYEPIVSVLNEKKTYHVHVLGDESLDSDV-THIKAYLF---DEKESIYHTFYESDIAFVS------------VGGNHLTDVAKSLADIFN-----------------RFGIQKKIKNIIVCENWRDAANTFKTAMLKFLNEENKNL---FEEFIGVSEAVLMRTATQPDEELAKLYPQ--------DVWVQNFWYLPIDGSRIKEAIP-KIQCVELLDEFGNFLTQKMYTNNTSNAVIAYSGYLLGYEILAEAANSLEISALLDDAYKEINQILVAELGVDEkeFSQKARAKYCDWTIVDKVIRHGKDPIRKLgdRLIAPCRMALKHGIYPKTLIDTIAKALYFDEPSDVEAVKL-----------KMLRQQKGIEYVLQTVC--------GLDKTERLYHEILKSVEQIKEQGLVK--------
207 UniRef50_B1A1C6 Altronate oxidoreductase/ma... 178 4e-43 1 20.0% 269:473 8:218 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PFEKAgiIVTDNQAPYRTRKVRILNGAHTLMVPVGLLAGIPTVRENIEDATVGQFVNDALTQEIIPSLPA-AEGLTEFKDDVLDRFRNPFIQHYLKSISLNSFPKFKTRVLPSIVSYMEKEQkpAYLSKSFASLIKLYDPKNKVGFEAQDNADVVELLGTVWEEYRSedELVKKVLSYDTLWEADLSVNTLLVEEVSKSLREIES-------------
208 UniRef50_B0P355 Putative uncharacterized pr... 175 2e-42 1 14.7% 17:417 6:361 ----------------RLKMKKELLVIGAGNIGRGVIGGLF--------FESGYHLYIYDIMEERMKQLKEQ-GTYLIERVGANNKRRVLV-----------DDFD-VLD-------------------CSDTVDLIEHMKKVDLIACCVYEGAFQSICQNLKEAIEYRTEQEAAPLNILLCVNALGAPDYFETELAKLLQN-NPAASRYLKEKIGICQVMV--------GMAAMPSSEELIAEDAFAVTTKLDGHIGieEPFKGELPQVKQTGGVQKGKAQIY--RKVYTGNMKHCMLAFLGKAKGYTYIRDTYDDGWIEDCVLGAFFeaIQAEYQFDETDHQEWIDFIVEAPKNRNLKDAFTRVAADPKTKLSrrFVGPALLCMKHHILPFYLAKGIAYGFLYRDESDIASIEIT---------------------------------------------------------------------
209 UniRef50_C5J772 Mannitol-1-phosphate 5-dehy... 174 7e-42 1 15.4% 23:431 2:343 ----------------------KAVHFGAGNIGRGLIARIYQQNN--------IEMIFVDVNPDLVNNLNQQK-TYKIIEI-TSNQEFHISN-----FHALHVNDENLIEHLKSAD--FVSTSIG-----------------------VNNLAKLQPIFNKLSE-----VETHLKQ--IICFEN----GFQISSLFAKMLKTNNF----W-----TFVDVTVDQIIPNINKS-------------SLDVIVENHYEIVLNDLDQQHKLDF----VIYSKNLQYFAIRKFLLVNVLHSTLAYLGFRKGYKFIHETLQDSTILHFikKVLFSIVLKHSQNQNVDLESYFQTNISRFKNKELKDEITRVARNPITKIGKnlLQEAKKLHLDSNKLDIIYQCFANILGFNFSQDQQSFNmeLDNDAYEFLKKHTN-------------------------------------------------------
210 UniRef50_B0MBC7 Putative uncharacterized pr... 170 1e-40 1 14.6% 28:478 8:384 ---------------------------GAGRLGKGFFGETFDNA------GWKIA---FLDKDPRVVEELKRTGSYHV--------EVHRVDSIE---------------------------NRTVSGYEAYVCDENYSCMDAFLNTDViyPKDFREAGHYLSKCFTEFYkqPEKKLTAICVTNKNY---LIPEIIESFKEKLPDDVKAWFDTNVAVRDSIIRRGTDAQTHYATE-------------IVTMAVASLLIQTPVYNDFSDVEW--LELNDQIETLKDLKVFAINGPHASTAFWGYLKGYKTIPDAEKDEEIAGIIYQaiLDMIMEEYDITKEELDH-----LENLPTpeIPDSIYRVAFDPIRKlgDRLTGAAQRCLKHGLPYEAIAKGMAAGFGYTEPEDENAVKLQ------EEIKEL-----GIEETVHKY--------TKLEKDSPILRKVVEEYEALKDRGLIK--------
211 UniRef50_Q4A9D2 Mannitol-1-phosphate 5-dehy... 169 2e-40 1 13.9% 23:417 2:327 ----------------------KVVHFGAGNIGRGLIAKLYHQNQFE--------IIFVDVNQNLVNDLNKNGFYYVINFENGEKYK------ITNFQAIHLNNKENLLKKLSSAD--IISTSIGAK-----------------------NLVFLKSIFAKLAKIEEKHKQ-------IICFENGYRVSSYFKT-ILEKCQFWN------------FVDTTIDQIAPSSND---------------LNVYTETFSEIILEEKQQK----IKLKTVEYLENLDFFILRKLFFVNALHSGIAYFAYNLKFNFINEALNSVIIQNYIEK-MKeqQTVLIINPLIemNEYFETTIKRFKNPVLQDLVVRVARNPITKISKnlLKYAKKSKISSEKLSIIYETFAYILNFDWENDNQALEMQ---------------------------------------------------------------------
212 UniRef50_C9AC43 Predicted protein n=1 Tax=E... 167 8e-40 1 14.3% 28:476 10:385 ---------------------------GAGRLGKGFVG--------ETFFNAGWKL-TFLDRDPRVIQELKKRNYYDVKVhtDDVYTTRV------------EGYEAVL---------------TDENYSVMDS-----FLSTDLLMMTLYPQDFQASAEYLAKCFNKQYKAknSKKTLICLTNKNhntSHFRKCLL------DDDVRAWFDKNVVIRDSIVRR----STDAEDSYSTDL---------VTTAVASLIIQGPVYSDFSDVEWLDVR--DNVEMLKDIKVFTINGPHAATAYYGYLKGYKDISSAQSDPEVSKLVKKVHDATLHAVLFEYPVTRDEIReeYLPKAKN-EMPDAIYRVAFDPIRKVGarFMGVITLCEKYGIDYGGIAKAIACAFAYDDPNDAN----------ALELQAEISSQGLSSTIAKYIGRHEG---------DQVVGEILKEYKKMEAQGI----------
213 UniRef50_Q5IMD1 Mannitol-1-phosphate dehydr... 165 3e-39 1 21.2% 30:302 1:218 -----------------------------GNIGRGFIGKLLADA--------GIQL-TFADVNQVVLDALNARHSYQVHVVGETEQVDTVSG--VNAVSSIGDD---VVDLIAQ-----VDLVTTAVG-----------------------PVVLERIAPAIAKGLVKRKEQGnsPLNIIACENMVRGTTQLKGHVM---NALPEDAKAWVEEHVGFVDSAVDRIVPPSASAT----------NDPLEVTVETFSEWIVDKTQFKGALP-NIPGMELTDNLMAFVERKLFTLNTGHAITAYL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
214 UniRef50_Q98PH2 Mannitol-1-phosphate 5-dehy... 165 4e-39 1 15.4% 23:445 5:358 ----------------------KALHFGAGNIGRG----LISDIYMKNNMD-----FALVDIDKDLIEKLNKQKSYSII----DFQTNKVFQ-ISNFKAFSIDQEDEIKKWIEQAD--FISTSIG---------------------------------WSNLASLKKFFENVKLKEKAQIIC---FENGYKISSFFQSILNI----------DSNHFVNASVDKIIPNFKS-------------DSLDVYVESYYEIILEQ---KNESQKKLNFVNYSTDLEAYINKKLFLVNAIHSTIGYLGYLKKYTYINEALNDQQILFKIKRliNEILSKEYLLFKVdlNDYLEKNLKRFSIKENQDLISRVARNPIQKLSKNERYFLIYNlkHNLEIDILLEIYKSIFYYDNKMDKESSKIQSTIelAYALKKFSNLDQEDQEKILKSLA-----------------------------------------
215 UniRef50_P55800 Mannitol-1-phosphate 5-dehy... 163 1e-38 1 11.7% 25:407 4:325 ------------------------IHFGAGNIGCGFIAPIL----------SSIV-----------------DHIYFV------DNNIDIVNKI---------NTQKLIKIHTSDSKKISITNIS-AWLLTDFINYKKTWNEVSLLTISIGIKNLKHIIYYVNQLIDYKIKNNQK-LIIMCCENGIRVSSLFKSYFSN------------LNNNIYFVDVLVDRIVSN-----------KNILNDYL--ECEDYYLWIVDKTQL--PSDFKQvnLTYTTSFDIQITKKIYMLNALHCSLAWffSFNKYLYVYQALKNDKVVEFVNNYLNEVILVLNHKYNINLDeyKNQIIKRLNSNFIKDDLKRLARNTELKLSkrILTILDYAKDNNLKHDILLLSYQNGLEYLK-------------------------------------------------------------------------------
216 UniRef50_D0NDP9 Putative uncharacterized pr... 161 5e-38 1 17.7% 27:415 38:403 --------------------------IGSGRFLRC---VLVPTLRAAGSA----VVVAQTRGTSFASACAKAEGKYEVDTIQNDGseVEAVGSLGDA-----EGRAAFMQLPSksKLKFIGFGVTESGIV---------KGGPAIVD--------------LTELLYnfTTQPNNIVSVINTDNLPKNGDTIKKLVLKTEWKGQPsfRAYVTSNVHFHNTMVDRLTS------HRAGDSLVPLTEPWPTKT-----LVIED--VHGVLDANkpGLHIRTTAGQLEqlKLSIANAVHTAMVYLLALTRVKTTCDVLKYPEIRQYLDLLYANDVAPSLELRGieAQHTYDEWMSRVEHKHFGLDNFWVGQNAMLKYGVRLFSTVEANveKYRPSVFMAFATALILRYLTPTQSDSRK-----------------------------------------------------------------------
217 UniRef50_B2HZL0 Predicted phosphatase/phosp... 160 8e-38 1 19.8% 53:415 247:661 ----------------------------------------------------GIHGFGAIGGGYIAQILSHWDG-YTKPKRIIASTRNSLFREAVNAFGTYSIRYGQF-----SYDERIENMTIVDS---DNEQQMLEMYTHSSLIALCLPEQAIEPESKIIAKGLYARFNSQLepLTFLIILNKVGAkkHLKEALLELTN--DEDVTEHILKEHYFCDTVVNRMVsnFLEQHLEDVEQeiEIEDCNKLNQEQLNQASieTDMpkGSPLLEKlqVVLVDQITDIQLIKNRLWNGVHAMLAWYASLMGYESIGVAMGDHLVKAFAENLIAEVKQGLAIV----LPNYAKD-LDRMSQSFlkDPCQRVARDPLRKlnERVMASIAVNICHDLPYKNlaLGYAYAIQFLEIEETKAVE-----------------------------------------------------------------------
218 UniRef50_B7G4T6 Predicted protein n=1 Tax=P... 155 5e-36 1 17.9% 27:422 40:437 --------------------------LGTGRFLRS---VLVPALNSFSHS----VLVQTRGRS-FLEYMATQDgtFPVDTVLPSGEIKT-----DRYRCYGAFSWGRVEDKAAFYDVsvIGVGVTEAGLASSETQAMKDldFLEYYQDMWEERSLWKPAL-----------TPHKKLCVIDMDNIPQNGDVLARHMNSLAQD-NARMLRFLADKVVFLNTMVDRITS-----------HREG--DPMVPKAEPvkALVILDSEGDLPVAFHKmgVVVRSTRAELeaLKLRVANGTHTALAHILALTKRTMTddGVAGPLLLAYLDALVETQILAAGGASGLEPHATaqDWRSRLTHPYFGLSSFFITQNGAAKGGIRLGPTVLDLVTRSQTTqaMAFAWACLLRWLTpeDEKSSRYSLTEEM----------------------------------------------------------------
219 UniRef50_P78008 Mannitol-1-phosphate 5-dehy... 150 9e-35 1 13.3% 21:447 3:360 --------------------RINVLHFGAGNIGRGVILPIYQQ------NDFSIDLVEL--NQNTVNELQKQK-QYQVHYLDCDQSQL-----VNDFNTWNLKDEAKIIELMERADV--ISTSIGAK-----------------------NLASLKTLFDK--AKFHKR--------AIVLC---FENGFRISSNFKNILQLNN--------TQVNFVDVVIDTIAPNFEKKA-----------NFLDIYCEKYSEIYAET------FPLEIKGVNQKNSLDRFIIKKLLLVNALHSVIGLLGFQQKLKYVHETLQVKSNLTFVEKLAQQIIDALCAEYPenLLSYGKNNLVRFANPKIQDLNTRLIREPLRKLNqrFYAIYKLFKKNKIALNNILQVYLMVLKTNITDDTESQQIaiNEKAWTELAKLSSLEESEWNLIKQELSRE---------------------------------------
220 UniRef50_C0D448 Putative uncharacterized pr... 150 1e-34 1 15.5% 22:473 2:396 ---------------------EKVVVIGAGRSGRGYVGELYDLE--------GYEITYADIDQELVDRLNGQ-GYYTVFKIDEDgeEVRRITGY-RALHTIRDH-RAYIDAIVEADY---VSTAT------------FPDGFDAISDD-------------IVEALRERMKRGIkpMAITVGANYVGVYDYYSK---RIGDQLSGEEREYLNTYMPLVESIIRR-ASSYPTEEQKKVDELAIQGDCLnvERNAFRF-----GEGHGLPKF----FKMVDNVKREMIIKIWIGNTLHCSYAYLGQYYHLHSSFEAAVNDYVSkyACEEAYNAVAKQLGLPMPRPVKEWQGIWTYYRNPSLQDTVLRIGADPIRKLSrrFIGPALMSLENGDVPVFICRNAAYGFVFANPE----------DPSACRLQEMIREQGIEKTIVD-------VCQLDLTqdKVVYDLILQSYKEIIS-------------
221 UniRef50_UPI0001903370 D-mannonate oxidoreductase ... 147 8e-34 1 36.3% 304:474 1:172 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YIGGYEFIRDVMDDAALAALAYRHMHAAARTLDPVPGINLDDYANELIARFANKAIAHRTYQIAMDGTQKLPQRLLEPACEALAHGDRAETYAIAVAAWMRYAIGEHGNGERYELRDPRAAEIEALIADvrTGPAISAALFTLPGLFPKTLTEHRAWAQDVSDKLEILIQD------------
222 UniRef50_A8RA67 Putative uncharacterized pr... 141 8e-32 1 15.4% 24:405 4:312 -----------------------IVLIGAGQTGRGYLNRFFKD-----------EKVTFLDIDSELIERLQQEKKYNIF-FGKQRETLTL-----DNFKAYTVDSKQGLDALAQADLVMIS----------------------------VGQKNLDSLVPLIQKALAIRQKGDVDILT-------AENGVHTKNYLIPLCQDKRVHLAETI----VFCTTL--------------------KQENSLDVFSEDLDYLPYDVVSLGHQLPYKHTVAE--KNLSSLMQRKIYTYNCLSAVVTYLGYYKGYEEYAKAANDSEITMCMDNILQKLNACICKEYEIDVDefSQMAVAKFQNKAIVDTIERNARDVDRKLgeRILAPLCILKKYGKQSDELLLVAACAVYY---------------------------------------------------------------------------------
223 UniRef50_C4U352 Mannitol dehydrogenase C-do... 121 8e-26 1 16.7% 114:394 12:281 -----------------------------------------------------------------------------------------------------------------DADLQLIDRLQSARGyqHIPLAAALHPADPQLQEWLAQATVITTSVRK--ENLHHVASanCAPKTVICCENIEQSGAF----FASLLQEAGVDDQHW-----SLPDCMVDRICSSHWPQTLEIEAESYGS-----ICVQALENAIIPDKF------------EITENIAARFQEKRILVNTYADGISFIGRAMGLEFLYQAAADQRINHLIDDYMQVMKIYllSPQHLDTMEQRHR--QRLANTAIKRPLDTVARNFLAKigERFIYPLIELARRDINIDR--------------------------------------------------------------------------------------------
224 UniRef50_C6N2H1 Putative uncharacterized pr... 119 3e-25 1 16.6% 25:338 24:336 ------------------------IH-GGGNIGLGLMADVINRSNFLEPYQ-----IIATSNDITFNTLINGNHQFRLQHIGADEGDDTVVSHITMTQRNHTD----IVKLYTD---------TTE------------------IIALCLTQNAFDESSESIAQGLINRYKQSKSNLTVLVLMNRHHCDKYVRETifKIGELIDDKTKreILERIEFIPTVSDRIVSKIPVEIVkeLKQQlgYDDSGTLETEINE--IIEDplFNAEIPfeLSSIDGVEDLDILAVIKDKYINGPHAILAWVSALFNCVTIAQGINYPGMKNYIASLMDVEIAPTLKK----------------------------------------------------------------------------------------------------------------------------------------------------
225 UniRef50_Q0FE81 Mannitol-1-phosphate 5-dehy... 116 2e-24 1 17.9% 223:412 123:320 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDIYFGVPDVIASLTASTENLedPNALHTEN-GVLYLEDhdITDCLKDLTPGIHWIddQMKSedAKLYLHNTPHCIAAFYGYLFECKYVHEALAIEEVSIILEGVVDEILQMLKILTNHdmEAYAKKEIRRFSNNLLFDPVIRVAREPIRKlgGRLLGALRMCISAGISPVNLTKGIVAALKYNEKNDPD--------------------------------------------------------------------------
226 UniRef50_B1EK89 Mannitol dehydrogenase C-do... 97 2e-18 1 17.3% 218:443 14:217 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDCMVDRIcpASTLIEAESWGTVCIQKLEGATTVQKFEQ---------------------VENITLRFQEKRILVNTYADGISFLGLAAGKQYLYQAAESEEIRLAMDNYMQLMKLYLCQECHLD-ANYLEKMAerLCNPHIKRSLESVARNFLQKIgeRFIYPLTVLQQRGVDIQP-------AISFLN-VLINGWANAQSEPQLARQQALASLN--VAEIVERL-------------------------------------------
227 UniRef50_C0VS89 Putative uncharacterized pr... 96 4e-18 1 30.8% 369:485 28:140 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DASDRIPKWLLPVVRENLKHDRKVTLSAAIIASWARYTEGVDEEGEPITIVDRMADRLHATAQGNKDN---IFAFLEDEEVFGEE-AHDERFRKPYAAVLESLHEIGSAKTVEKLIA-
228 UniRef50_O96437 Mannitol-1-phosphate dehydr... 91 1e-16 1 13.4% 13:302 166:421 ------------PKGPHKLLPTPHLHFGAGKLGCGLV---LQAMLRSNVED---LVVLQRQSEDFEPLLSAAKReiPVFVNGEKVCELLV--------YVHPNEIEELIQKLENKKLQNSKstSTHLVLTNDSELALKLAKAAKSLSCSLGPAMETALLPLLSQLPDT---PKTEQVLLYACENDHAAVARLKE---------------QLQQKVLVLPCMVDRIC-----------AARNIFADKIEVSAEPYEgvVLERPQFAPPPPFGGPNVhlRAAAHYLCQRKIGLVNGMHTTLAFL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
229 UniRef50_UPI0001C36157 fructuronate reductase n=1 ... 78 6e-13 1 31.6% 8:86 17:101 -------AGIGLPSYDLETLapVWVHFGIGNIFRIFIGSIADRLITDGLMDRGIVCVETFDYETIDRIYKPYDNLCLSVILHNDGS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
230 UniRef50_UPI0001AEC5E5 D-mannonate oxidoreductase ... 71 6e-11 1 28.6% 370:474 1:102 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSAKLPVFLFPTVRDNLAANRDTDISALVVACWAFydRHASQDGKSLEINDVLADKLHNAASNNQIDS---LSFLMLEEVFGK-LVDEARFTASFQGFVERLYQQ------------
231 UniRef50_D0RMY4 Mannitol-1-phosphate 5-dehy... 52 5e-05 1 13.4% 20:317 1:217 -------------------MSTKILIYGAGAIGRGFLAY--------KFSNERYELSFVDKNRRLIELLKKRDFFYSVC-----------IKKKNYKFKKIFFKDAFYIDEI-------------------------IDIKKYDFVFCCVGPNQSYEIA-----------KNFSKAKNVISCENDIN-------TVEGIKNLSN-------NNNIFfpDV----ITSNT-------ASPNLLKKDELTIVSE-DGELILENLKKFKKLKEAKKVSKSIFKMHWY--AKFFIHNAPHALLAYLGWMKKYKFIHEAMAD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
232 UniRef50_UPI0001694256 Mannitol-1-phosphate/altron... 46 0.002 1 18.2% 410:486 4:90 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDKGEPFKVsdPLMDVLQGHLRNINIEDNslKPILSNHEIFGMNLYEI-GLGERIETYFQDMIQkaVRNTLHQVVEE
233 UniRef50_C1N0F1 Predicted protein n=1 Tax=M... 45 0.009 1 16.3% 25:472 90:555 ------------------------VHFGAGRLG---FGLVIPALESSGSP----YIVMNRPSAVWA----------PVVEREKEAQQHVAvtCGGRGLHVITEDD---IRAHEEGILGIVHDALENGARGFLLLSMDVNLCAPVIAQATSFSCALGPAVQVLADHllPDVEDETRPV-LYACENDHSSVEKL-----QFA----------LRTKVEAVPCMVDRIclTVSDDAKTVNVTAEGHEGSIVVLNQPESA---DGKKEQGPLAGDFvnPENEADSSYLYRKKLLTVNGMHTVIAFRTllLSDETVTDEQRAEIWsaQVLVLMWEHGIPtmRVHGQdlLDQLRTTLDRFF--TIEDSTARvgGGVSLRYEGRLLPTYeeLLTAGWTPDCAQNVlaGLELESLQTddEARPFAAVDKRARAMKELEEAMKEEQARstTALAWEAV---GLPPVEEVRAKFQESFEIIQ--------------
consensus/100% ......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
consensus/90% ........................hG.G.hhhsh....................h...............t..h.h...................................................................................h..hh..h.t.....h.hhshp.h..ss..htt.h.t..............t...h..shlDphs.........................p....hhlpt............th.h..ph..h..hKhhhlNs.Hs.hs..u.h.t.t.h.p.htt..h...h.thh.............p..ta.t.h.tRh.s..h.c...pls.ts..Kh..h.h..h....t.t.........hs.hh.h................................................................................
consensus/80% ..................hlphG.GshhRua.s.hht..........th..ht.h........h..ppt.a.l...s.t..p.phht.h.thh.......tthhthh.t.th.hh..sh............................t...th..hlhthh..hhttt..shslhss-.h.tsuthhpt.lhthht....th.thhttt..assshVDRIsst................s.h.h.sE.a..hhl-t...tt...ht..sh.hstslt.a..hKlhhlNssHshhshhu.hhGhphltpshtp..h.thhpthh.pphh.hh...t.phttahtthhtRFtNshltc.h.pluhss.tKh..Rhh.sh...ht.s...thhhhshAshhha...............................................................................
consensus/70% ...............thlphG.GshhRua.shhhpth...t..p.shhhht.hs.tthhtthttpcthYslh.hs.p.pphpllssl.phh.s..p..tthhthhtpsththl..shT-tuh..................t....t..tphhshlsttlhtRhtttttshsllsC-Nh.tNGthlcphlhphht.hs.thhtaltptstFssohVDRIsPs.stt..t.h.t..thtD.h.lhsEsah.WllEsp.htsp.shphsGs.hsssltsapphKlhhLNusHshhuhhuhlhGhphlt-shtc..htthlpthh.pphhshl...t.-httahptllpRFtNshltcph.pluhss.pKh..Rhlsshhthhttst..thhshslAuhhhah...t.ts..h...-.....h.t.h............hh.........h.t...h.t.h...ht.h............
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