Phyre 2 Results for P46850

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Email | l.a.kelley@imperial.ac.uk
Description | P46850
Date | Thu Jan 5 12:04:22 GMT 2012
Unique Job ID | c6e4a64e36197fd1

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1uc2a_
Top template information
Fold:Hypothetical protein PH1602 Superfamily:Hypothetical protein PH1602 Family:Hypothetical protein PH1602
Confidence and coverage
Confidence: | 100.0% | Coverage: | 100%
406 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | N | Y | E | L | L | T | T | E | N | A | P | V | K | M | W | T | K | G | V | P | V | E | A | D | A | R | Q | Q | L | I | N | T | A | K | M | P | F | I | F | K | H | I | A | V | M | P | D | V | H | L | G | K | G | S | T | I | G | S | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | I | P | T | K | G | A | I | I | P | A | A | V | G | V | D | I | G | C | G | M | N | A | L | R | T | A | L | T | A | E | D | L | P | E | N | L | A | E | L | R | Q | A | I | E | T | A | V | P | H | G | R | T | T | G | R | C | K | R | D | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | G | A | W | E | N | P | P | V | N | V | D | A | K | W | A | E | L | E | A | G | Y | Q | W | L | T | Q | K | Y | P | R | F | L | N | T | N | N | Y | K | H | L | G | T | L | G | T | G | N | H | F | I | E | I | C | L | D | E | S | D | Q | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  | ? | ? |  |  |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | W | I | M | L | H | S | G | S | R | G | I | G | N | A | I | G | T | Y | F | I | D | L | A | Q | K | E | M | Q | E | T | L | E | T | L | P | S | R | D | L | A | Y | F | M | E | G | T | E | Y | F | D | D | Y | L | K | A | V | A | W | A | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | L | F | A | S | L | N | R | D | A | M | M | E | N | V | V | T | A | L | Q | S | I | T | Q | K | T | V | R | Q | P | Q | T | L | A | M | E | E | I | N | C | H | H | N | Y | V | Q | K | E | Q | H | F | G | E | E | I | Y | V | T | R | K | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | A | V | S | A | R | A | G | Q | Y | G | I | I | P | G | S | M | G | A | K | S | F | I | V | R | G | L | G | N | E | E | S | F | C | S | C | S | H | G | A | G | R | V | M | S | R | T | K | A | K | K | L | F | S | V | E | D | Q | I | R | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | .
Sequence |  | T | A | H | V | E | C | R | K | D | A | E | V | I | D | E | I | P | M | A | Y | K | D | I | D | A | V | M | A | A | Q | S | D | L | V | E | V | I | Y | T | L | R | Q | V | V | C | V | K | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1uc2a_ |

### PDB 1uc2 chain A

Region: 2 - 408
Aligned: 406
Modelled: 407
Confidence: 100.0%
Identity: 29%
Fold: Hypothetical protein PH1602
Superfamily: Hypothetical protein PH1602
Family: Hypothetical protein PH1602

Phyre2
2 |
| c2epgB_ |

### PDB 2epg chain B

Region: 3 - 408
Aligned: 380
Modelled: 383
Confidence: 100.0%
Identity: 31%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein ttha1785;
PDBTitle: crystal structure of ttha1785

Phyre2
3 |
| d1el6a_ |

### PDB 1el6 chain A

Region: 17 - 73
Aligned: 54
Modelled: 57
Confidence: 56.3%
Identity: 26%
Fold: Baseplate structural protein gp11
Superfamily: Baseplate structural protein gp11
Family: Baseplate structural protein gp11

Phyre2
4 |
| d1xmta_ |

### PDB 1xmt chain A

Region: 163 - 205
Aligned: 43
Modelled: 43
Confidence: 52.7%
Identity: 19%
Fold: Acyl-CoA N-acyltransferases (Nat)
Superfamily: Acyl-CoA N-acyltransferases (Nat)
Family: N-acetyl transferase, NAT

Phyre2
5 |
| d2pd4a1 |

### PDB 2pd4 chain A domain 1

Region: 177 - 201
Aligned: 25
Modelled: 25
Confidence: 47.7%
Identity: 8%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2
6 |
| c2btwA_ |

### PDB 2btw chain A

Region: 157 - 183
Aligned: 26
Modelled: 27
Confidence: 43.5%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:alr0975 protein;
PDBTitle: crystal structure of alr0975

Phyre2
7 |
| d1fxkc_ |

### PDB 1fxk chain C

Region: 55 - 105
Aligned: 51
Modelled: 51
Confidence: 35.0%
Identity: 16%
Fold: Long alpha-hairpin
Superfamily: Prefoldin
Family: Prefoldin

Phyre2
8 |
| c3emkA_ |

### PDB 3emk chain A

Region: 177 - 201
Aligned: 23
Modelled: 25
Confidence: 34.4%
Identity: 22%
PDB header:oxidoreductase
Chain: A: PDB Molecule:glucose/ribitol dehydrogenase;
PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis

Phyre2
9 |
| d1hxha_ |

### PDB 1hxh chain A

Region: 177 - 201
Aligned: 23
Modelled: 25
Confidence: 31.9%
Identity: 22%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2
10 |
| d2bu3a1 |

### PDB 2bu3 chain A domain 1

Region: 157 - 183
Aligned: 26
Modelled: 27
Confidence: 29.4%
Identity: 19%
Fold: Cysteine proteinases
Superfamily: Cysteine proteinases
Family: Phytochelatin synthase

Phyre2
11 |
| c3grkE_ |

### PDB 3grk chain E

Region: 177 - 201
Aligned: 25
Modelled: 25
Confidence: 27.4%
Identity: 16%
PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis

Phyre2
12 |
| c2jjyD_ |

### PDB 2jjy chain D

Region: 177 - 201
Aligned: 25
Modelled: 25
Confidence: 26.7%
Identity: 8%
PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of francisella tularensis enoyl reductase2 (ftfabi) with bound nad

Phyre2
13 |
| c2zdiC_ |

### PDB 2zdi chain C

Region: 55 - 105
Aligned: 51
Modelled: 51
Confidence: 25.6%
Identity: 27%
PDB header:chaperone
Chain: C: PDB Molecule:prefoldin subunit alpha;
PDBTitle: crystal structure of prefoldin from pyrococcus horikoshii2 ot3

Phyre2
14 |
| c3ek2D_ |

### PDB 3ek2 chain D

Region: 177 - 201
Aligned: 25
Modelled: 25
Confidence: 25.4%
Identity: 12%
PDB header:oxidoreductase
Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b

Phyre2
15 |
| c2c4rL_ |

### PDB 2c4r chain L

Region: 333 - 344
Aligned: 12
Modelled: 12
Confidence: 24.9%
Identity: 33%
PDB header:hydrolase
Chain: L: PDB Molecule:ribonuclease e;
PDBTitle: catalytic domain of e. coli rnase e

Phyre2
16 |
| d2h7ma1 |

### PDB 2h7m chain A domain 1

Region: 177 - 201
Aligned: 25
Modelled: 25
Confidence: 24.5%
Identity: 8%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2
17 |
| c2bpbB_ |

### PDB 2bpb chain B

Region: 330 - 361
Aligned: 32
Modelled: 32
Confidence: 20.5%
Identity: 9%
PDB header:oxidoreductase
Chain: B: PDB Molecule:sulfite\:cytochrome c oxidoreductase subunit b;
PDBTitle: sulfite dehydrogenase from starkeya novella

Phyre2
18 |
| c2o2sA_ |

### PDB 2o2s chain A

Region: 177 - 201
Aligned: 25
Modelled: 25
Confidence: 20.4%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-acyl carrier reductase;
PDBTitle: the structure of t. gondii enoyl acyl carrier protein reductase in2 complex with nad and triclosan

Phyre2
19 |
| d1jmxa1 |

### PDB 1jmx chain A domain 1

Region: 330 - 347
Aligned: 18
Modelled: 18
Confidence: 20.1%
Identity: 11%
Fold: Cytochrome c
Superfamily: Cytochrome c
Family: Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2

Phyre2
20 |
| c2quoA_ |

### PDB 2quo chain A

Region: 162 - 192
Aligned: 30
Modelled: 31
Confidence: 19.6%
Identity: 33%
PDB header:toxin
Chain: A: PDB Molecule:heat-labile enterotoxin b chain;
PDBTitle: crystal structure of c terminal fragment of clostridium2 perfringens enterotoxin

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1uc2a_ |
|  | 100.0 | 29 | Fold:Hypothetical protein PH1602 Superfamily:Hypothetical protein PH1602 Family:Hypothetical protein PH1602
2 | c2epgB_ |
|  | 100.0 | 31 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ttha1785; PDBTitle: crystal structure of ttha1785
3 | d1el6a_ |
|  | 56.3 | 26 | Fold:Baseplate structural protein gp11 Superfamily:Baseplate structural protein gp11 Family:Baseplate structural protein gp11
4 | d1xmta_ |
|  | 52.7 | 19 | Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT
5 | d2pd4a1 |
|  | 47.7 | 8 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
6 | c2btwA_ |
|  | 43.5 | 19 | PDB header:transferase Chain: A: PDB Molecule:alr0975 protein; PDBTitle: crystal structure of alr0975
7 | d1fxkc_ |
|  | 35.0 | 16 | Fold:Long alpha-hairpin Superfamily:Prefoldin Family:Prefoldin
8 | c3emkA_ |
|  | 34.4 | 22 | PDB header:oxidoreductase Chain: A: PDB Molecule:glucose/ribitol dehydrogenase; PDBTitle: 2.5a crystal structure of glucose/ribitol dehydrogenase2 from brucella melitensis
9 | d1hxha_ |
|  | 31.9 | 22 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
10 | d2bu3a1 |
|  | 29.4 | 19 | Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Phytochelatin synthase
11 | c3grkE_ |
|  | 27.4 | 16 | PDB header:oxidoreductase Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh); PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
12 | c2jjyD_ |
|  | 26.7 | 8 | PDB header:oxidoreductase Chain: D: PDB Molecule:enoyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of francisella tularensis enoyl reductase2 (ftfabi) with bound nad
13 | c2zdiC_ |
|  | 25.6 | 27 | PDB header:chaperone Chain: C: PDB Molecule:prefoldin subunit alpha; PDBTitle: crystal structure of prefoldin from pyrococcus horikoshii2 ot3
14 | c3ek2D_ |
|  | 25.4 | 12 | PDB header:oxidoreductase Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh); PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b
15 | c2c4rL_ |
|  | 24.9 | 33 | PDB header:hydrolase Chain: L: PDB Molecule:ribonuclease e; PDBTitle: catalytic domain of e. coli rnase e
16 | d2h7ma1 |
|  | 24.5 | 8 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
17 | c2bpbB_ |
|  | 20.5 | 9 | PDB header:oxidoreductase Chain: B: PDB Molecule:sulfite\:cytochrome c oxidoreductase subunit b; PDBTitle: sulfite dehydrogenase from starkeya novella
18 | c2o2sA_ |
|  | 20.4 | 24 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: the structure of t. gondii enoyl acyl carrier protein reductase in2 complex with nad and triclosan
19 | d1jmxa1 |
|  | 20.1 | 11 | Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2
20 | c2quoA_ |
|  | 19.6 | 33 | PDB header:toxin Chain: A: PDB Molecule:heat-labile enterotoxin b chain; PDBTitle: crystal structure of c terminal fragment of clostridium2 perfringens enterotoxin
21 | d1pbya1 |
| not modelled | 19.5 | 19 | Fold:Cytochrome c Superfamily:Cytochrome c Family:Quinohemoprotein amine dehydrogenase A chain, domains 1 and 2
22 | d1w96a2 |
| not modelled | 19.5 | 43 | Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like
23 | d2j9ga2 |
| not modelled | 18.9 | 27 | Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like
24 | c1jmuE_ |
| not modelled | 18.6 | 67 | PDB header:viral protein Chain: E: PDB Molecule:protein mu-1; PDBTitle: crystal structure of the reovirus mu1/sigma3 complex
25 | d1ulza2 |
| not modelled | 18.4 | 43 | Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like
26 | d1kx7a_ |
| not modelled | 17.9 | 27 | Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c
27 | c2ptgA_ |
| not modelled | 17.8 | 20 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: crystal structure of eimeria tenella enoyl reductase
28 | d1uoua3 |
| not modelled | 17.7 | 7 | Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain
29 | c2ig6B_ |
| not modelled | 17.1 | 13 | PDB header:oxidoreductase Chain: B: PDB Molecule:nimc/nima family protein; PDBTitle: crystal structure of a nimc/nima family protein (ca_c2569) from2 clostridium acetobutylicum at 1.80 a resolution
30 | c1w4zA_ |
| not modelled | 17.0 | 20 | PDB header:antibiotic biosynthesis Chain: A: PDB Molecule:ketoacyl reductase; PDBTitle: structure of actinorhodin polyketide (actiii) reductase
31 | c3gdfA_ |
| not modelled | 16.8 | 20 | PDB header:oxidoreductase Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase; PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
32 | c2nq8B_ |
| not modelled | 16.8 | 13 | PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: malarial enoyl acyl acp reductase bound with inh-nad adduct
33 | c2foiB_ |
| not modelled | 16.8 | 13 | PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: synthesis, biological activity, and x-ray crystal structural analysis2 of diaryl ether inhibitors of malarial enoyl acp reductase.
34 | c3svtA_ |
| not modelled | 16.4 | 21 | PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase; PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans
35 | d1xq1a_ |
| not modelled | 15.8 | 29 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
36 | d1wkqa_ |
| not modelled | 15.8 | 41 | Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like
37 | c3cu4A_ |
| not modelled | 15.7 | 27 | PDB header:electron transport Chain: A: PDB Molecule:cytochrome c family protein; PDBTitle: omcf, outer membrance cytochrome f from geobacter2 sulfurreducens
38 | d2rhca1 |
| not modelled | 15.7 | 21 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
39 | d1r0ua_ |
| not modelled | 15.3 | 24 | Fold:Lipocalins Superfamily:Lipocalins Family:Hypothetical protein YwiB
40 | d1ulua_ |
| not modelled | 15.1 | 20 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
41 | d1h5qa_ |
| not modelled | 14.2 | 29 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
42 | d1uh5a_ |
| not modelled | 13.1 | 12 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
43 | d2ag5a1 |
| not modelled | 13.0 | 29 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
44 | c3giwA_ |
| not modelled | 12.9 | 18 | PDB header:unknown function Chain: A: PDB Molecule:protein of unknown function duf574; PDBTitle: crystal structure of a duf574 family protein (sav_2177) from2 streptomyces avermitilis ma-4680 at 1.45 a resolution
45 | c3db0B_ |
| not modelled | 12.8 | 10 | PDB header:oxidoreductase Chain: B: PDB Molecule:lin2891 protein; PDBTitle: crystal structure of putative pyridoxamine 5'-phosphate oxidase2 (np_472219.1) from listeria innocua at 2.00 a resolution
46 | c2d0sA_ |
| not modelled | 12.6 | 17 | PDB header:electron transport Chain: A: PDB Molecule:cytochrome c; PDBTitle: crystal structure of the cytochrome c552 from moderate2 thermophilic bacterium, hydrogenophilus thermoluteolus
47 | c2v07A_ |
| not modelled | 12.3 | 27 | PDB header:photosynthesis Chain: A: PDB Molecule:cytochrome c6; PDBTitle: structure of the arabidopsis thaliana cytochrome c6a v52q2 variant
48 | c3gr6A_ |
| not modelled | 12.3 | 8 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh]; PDBTitle: crystal structure of the staphylococcus aureus enoyl-acyl2 carrier protein reductase (fabi) in complex with nadp and3 triclosan
49 | c3ku1E_ |
| not modelled | 12.0 | 40 | PDB header:transferase Chain: E: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine
50 | d2tpta3 |
| not modelled | 11.6 | 3 | Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain
51 | c2p91A_ |
| not modelled | 11.6 | 16 | PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadh]; PDBTitle: crystal structure of enoyl-[acyl-carrier-protein] reductase (nadh)2 from aquifex aeolicus vf5
52 | d1cc5a_ |
| not modelled | 11.4 | 36 | Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c
53 | d1qsga_ |
| not modelled | 11.2 | 16 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
54 | c3ckkA_ |
| not modelled | 10.8 | 100 | PDB header:transferase Chain: A: PDB Molecule:trna (guanine-n(7)-)-methyltransferase; PDBTitle: crystal structure of human methyltransferase-like protein 1
55 | d1mz4a_ |
| not modelled | 10.7 | 21 | Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c
56 | c3qivA_ |
| not modelled | 10.6 | 19 | PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier- PDBTitle: crystal structure of a putative short-chain dehydrogenase or 3-2 oxoacyl-[acyl-carrier-protein] reductase from mycobacterium3 paratuberculosis atcc baa-968 / k-10
57 | d1fcdc1 |
| not modelled | 10.5 | 33 | Fold:Cytochrome c Superfamily:Cytochrome c Family:Two-domain cytochrome c
58 | d1tt2a_ |
| not modelled | 10.4 | 10 | Fold:OB-fold Superfamily:Staphylococcal nuclease Family:Staphylococcal nuclease
59 | d1cyja_ |
| not modelled | 10.4 | 27 | Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c
60 | d1brwa3 |
| not modelled | 10.4 | 13 | Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain
61 | c3g5tA_ |
| not modelled | 10.4 | 80 | PDB header:transferase Chain: A: PDB Molecule:trans-aconitate 3-methyltransferase; PDBTitle: crystal structure of trans-aconitate 3-methyltransferase2 from yeast
62 | d1wvec1 |
| not modelled | 10.4 | 18 | Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c
63 | d2fd5a2 |
| not modelled | 10.3 | 20 | Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain
64 | c2bh1Y_ |
| not modelled | 10.1 | 23 | PDB header:transport protein Chain: Y: PDB Molecule:general secretion pathway protein e,; PDBTitle: x-ray structure of the general secretion pathway complex of2 the n-terminal domain of epse and the cytosolic domain of3 epsl of vibrio cholerae
65 | d2bh1x1 |
| not modelled | 10.1 | 23 | Fold:Alpha-lytic protease prodomain-like Superfamily:EspE N-terminal domain-like Family:GSPII protein E N-terminal domain-like
66 | c3dliB_ |
| not modelled | 10.0 | 100 | PDB header:transferase Chain: B: PDB Molecule:methyltransferase; PDBTitle: crystal structure of a sam dependent methyltransferase from2 archaeoglobus fulgidus
67 | c3bkwB_ |
| not modelled | 9.8 | 80 | PDB header:transferase Chain: B: PDB Molecule:s-adenosylmethionine dependent methyltransferase; PDBTitle: crystal structure of s-adenosylmethionine dependent methyltransferase2 (np_104914.1) from mesorhizobium loti at 1.60 a resolution
68 | c1j6qA_ |
| not modelled | 9.7 | 26 | PDB header:chaperone Chain: A: PDB Molecule:cytochrome c maturation protein e; PDBTitle: solution structure and characterization of the heme2 chaperone ccme
69 | d1j6qa_ |
| not modelled | 9.7 | 26 | Fold:OB-fold Superfamily:Heme chaperone CcmE Family:Heme chaperone CcmE
70 | c3lf2B_ |
| not modelled | 9.6 | 33 | PDB header:oxidoreductase Chain: B: PDB Molecule:short chain oxidoreductase q9hya2; PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center
71 | d1ja9a_ |
| not modelled | 9.5 | 25 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases
72 | c3fzgA_ |
| not modelled | 9.4 | 80 | PDB header:transferase Chain: A: PDB Molecule:16s rrna methylase; PDBTitle: structure of the 16s rrna methylase arma
73 | c3dlcA_ |
| not modelled | 9.4 | 80 | PDB header:transferase Chain: A: PDB Molecule:putative s-adenosyl-l-methionine-dependent PDBTitle: crystal structure of a putative s-adenosyl-l-methionine-dependent2 methyltransferase (mmp1179) from methanococcus maripaludis at 1.15 a3 resolution
74 | d1vz6a_ |
| not modelled | 9.4 | 12 | Fold:DmpA/ArgJ-like Superfamily:DmpA/ArgJ-like Family:ArgJ-like
75 | d2h00a1 |
| not modelled | 9.2 | 45 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Methyltransferase 10 domain
76 | d1xxla_ |
| not modelled | 9.2 | 80 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:UbiE/COQ5-like
77 | c2p35A_ |
| not modelled | 9.1 | 80 | PDB header:transferase Chain: A: PDB Molecule:trans-aconitate 2-methyltransferase; PDBTitle: crystal structure of trans-aconitate methyltransferase from2 agrobacterium tumefaciens
78 | c2qioA_ |
| not modelled | 9.0 | 9 | PDB header:unknown function Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase; PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
79 | c2p8jA_ |
| not modelled | 9.0 | 60 | PDB header:transferase Chain: A: PDB Molecule:s-adenosylmethionine-dependent methyltransferase; PDBTitle: crystal structure of s-adenosylmethionine-dependent methyltransferase2 (np_349143.1) from clostridium acetobutylicum at 2.00 a resolution
80 | c3dxyA_ |
| not modelled | 9.0 | 60 | PDB header:transferase Chain: A: PDB Molecule:trna (guanine-n(7)-)-methyltransferase; PDBTitle: crystal structure of ectrmb in complex with sam
81 | d2avna1 |
| not modelled | 9.0 | 60 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:UbiE/COQ5-like
82 | c3i9fB_ |
| not modelled | 9.0 | 80 | PDB header:transferase Chain: B: PDB Molecule:putative type 11 methyltransferase; PDBTitle: crystal structure of a putative type 11 methyltransferase2 from sulfolobus solfataricus
83 | c3l8dA_ |
| not modelled | 9.0 | 80 | PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: crystal structure of methyltransferase from bacillus2 thuringiensis
84 | c3k31B_ |
| not modelled | 8.9 | 4 | PDB header:oxidoreductase Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
85 | c3d2lC_ |
| not modelled | 8.8 | 100 | PDB header:transferase Chain: C: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of sam-dependent methyltransferase (zp_00538691.1)2 from exiguobacterium sp. 255-15 at 1.90 a resolution
86 | d1wfwa_ |
| not modelled | 8.7 | 20 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
87 | c2hxgB_ |
| not modelled | 8.7 | 24 | PDB header:isomerase Chain: B: PDB Molecule:l-arabinose isomerase; PDBTitle: crystal structure of mn2+ bound ecai
88 | c3merA_ |
| not modelled | 8.7 | 20 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:slr1183 protein; PDBTitle: crystal structure of the methyltransferase slr1183 from2 synechocystis sp. pcc 6803, northeast structural genomics3 consortium target sgr145
89 | c3opnA_ |
| not modelled | 8.7 | 60 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative hemolysin; PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis
90 | d2fk8a1 |
| not modelled | 8.6 | 100 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase
91 | d1kpga_ |
| not modelled | 8.6 | 80 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase
92 | c2fk8A_ |
| not modelled | 8.6 | 100 | PDB header:transferase Chain: A: PDB Molecule:methoxy mycolic acid synthase 4; PDBTitle: crystal structure of hma (mmaa4) from mycobacterium tuberculosis2 complexed with s-adenosylmethionine
93 | d1ctja_ |
| not modelled | 8.6 | 27 | Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c
94 | c2x5sB_ |
| not modelled | 8.5 | 11 | PDB header:transferase Chain: B: PDB Molecule:mannose-1-phosphate guanylyltransferase; PDBTitle: crystal structure of t. maritima gdp-mannose2 pyrophosphorylase in apo state.
95 | c3egeA_ |
| not modelled | 8.5 | 80 | PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase from antibiotic biosynthesis PDBTitle: crystal structure of putative methyltransferase from antibiotic2 biosynthesis pathway (yp_324569.1) from anabaena variabilis atcc3 29413 at 2.40 a resolution
96 | c3h2bB_ |
| not modelled | 8.4 | 60 | PDB header:transferase Chain: B: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of the sam-dependent methyltransferase2 cg3271 from corynebacterium glutamicum in complex with s-3 adenosyl-l-homocysteine and pyrophosphate. northeast4 structural genomics consortium target cgr113a
97 | c3g07C_ |
| not modelled | 8.3 | 60 | PDB header:transferase Chain: C: PDB Molecule:7sk snrna methylphosphate capping enzyme; PDBTitle: methyltransferase domain of human bicoid-interacting protein2 3 homolog (drosophila)
98 | c3tl3A_ |
| not modelled | 8.3 | 23 | PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase; PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans
99 | d2fcta1 |
| not modelled | 8.3 | 32 | Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:PhyH-like

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0