Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	L	S	L	S	P	P	P	Y	A	D	A	P	V	V	V	L	I	S	G	L	G	G	S	G	S	Y	W	L	P	Q	L	A	V	L	E	Q	E	Y	Q	V	V	C	Y	D	Q	R	G	T	G	N	N	P	D	T	L	A	E	D
Secondary structure
SS confidence
Disorder		?	?	?																																																						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	S	I	A	Q	M	A	A	E	L	H	Q	A	L	V	A	A	G	I	E	H	Y	A	V	V	G	H	A	L	G	A	L	V	G	M	Q	L	A	L	D	Y	P	A	S	V	T	V	L	I	S	V	N	G	W	L	R	I	N	A	H
Secondary structure
SS confidence
Disorder																																																								?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	R	R	C	F	Q	V	R	E	R	L	L	Y	S	G	G	A	Q	A	W	V	E	A	Q	P	L	F	L	Y	P	A	D	W	M	A	A	R	A	P	R	L	E	A	E	D	A	L	A	L	A	H	F	Q	G	K	N	N	L	L	R
Secondary structure
SS confidence
Disorder																			?										?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	L	N	A	L	K	R	A	D	F	S	H	H	A	D	R	I	R	C	P	V	Q	I	I	C	A	S	D	D	L	L	V	P	T	A	C	S	S	E	L	H	A	A	L	P	D	S	Q	K	M	V	M	P	Y	G	G	H	A	C	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
Sequence		V	T	D	P	E	T	F	N	A	L	L	L	N	G	L	A	S	L	L	H	H	R	E	A	A	L
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3v48 chain B Region: 2 - 262 Aligned: 261 Modelled: 261 Confidence: 100.0% Identity: 98% PDB header:hydrolase Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd; PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli Phyre2 PDB 1cr6 chain A Region: 3 - 257 Aligned: 255 Modelled: 255 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor Phyre2 PDB 2qmq chain A Region: 1 - 255 Aligned: 253 Modelled: 255 Confidence: 100.0% Identity: 14% PDB header:signaling protein Chain: A: PDB Molecule:protein ndrg2; PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution Phyre2 PDB 2r11 chain D Region: 2 - 257 Aligned: 250 Modelled: 256 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: D: PDB Molecule:carboxylesterase np; PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution Phyre2 PDB 2xmz chain A Region: 1 - 260 Aligned: 259 Modelled: 260 Confidence: 100.0% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:hydrolase, alpha/beta hydrolase fold family; PDBTitle: structure of menh from s. aureus Phyre2 PDB 2wj4 chain B Region: 5 - 261 Aligned: 257 Modelled: 257 Confidence: 100.0% Identity: 10% PDB header:oxidoreductase Chain: B: PDB Molecule:1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase; PDBTitle: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-2 oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter3 nitroguajacolicus ru61a anaerobically complexed with its4 natural substrate 1-h-3-hydroxy-4-oxoquinaldine Phyre2 PDB 2vav chain L Region: 1 - 257 Aligned: 257 Modelled: 257 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) Phyre2 PDB 3oos chain A Region: 1 - 255 Aligned: 251 Modelled: 251 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase family protein; PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne Phyre2 PDB 3om8 chain A Region: 1 - 257 Aligned: 252 Modelled: 257 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:probable hydrolase; PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01 Phyre2 PDB 3qvm chain A Region: 2 - 257 Aligned: 253 Modelled: 256 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:olei00960; PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica Phyre2 PDB 3i1i chain A Region: 1 - 257 Aligned: 257 Modelled: 255 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis Phyre2 PDB 2y6v chain B Region: 1 - 258 Aligned: 257 Modelled: 258 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) Phyre2 PDB 2xua chain H Region: 1 - 257 Aligned: 251 Modelled: 257 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: H: PDB Molecule:3-oxoadipate enol-lactonase; PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400 Phyre2 PDB 2b61 chain A domain 1 Region: 1 - 257 Aligned: 257 Modelled: 257 Confidence: 100.0% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: O-acetyltransferase Phyre2 PDB 3kda chain B Region: 3 - 261 Aligned: 259 Modelled: 259 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:cftr inhibitory factor (cif); PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation Phyre2 PDB 2e3j chain A Region: 1 - 258 Aligned: 258 Modelled: 258 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase ephb; PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom Phyre2 PDB 2rhw chain A domain 1 Region: 2 - 257 Aligned: 256 Modelled: 256 Confidence: 100.0% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Carbon-carbon bond hydrolase Phyre2 PDB 3fsg chain C Region: 1 - 258 Aligned: 253 Modelled: 258 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta superfamily hydrolase; PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1 Phyre2 PDB 1c4x chain A Region: 1 - 257 Aligned: 257 Modelled: 257 Confidence: 100.0% Identity: 16% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Carbon-carbon bond hydrolase Phyre2 PDB 2vat chain A domain 1 Region: 1 - 257 Aligned: 257 Modelled: 257 Confidence: 100.0% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: O-acetyltransferase Phyre2 1 c3v48B_ 2 c1cr6A_ 3 c2qmqA_ 4 c2r11D_ 5 c2xmzA_ 6 c2wj4B_ 7 c2vavL_ 8 c3oosA_ 9 c3om8A_ 10 c3qvmA_ 11 c3i1iA_ 12 c2y6vB_ 13 c2xuaH_ 14 d2b61a1 15 c3kdaB_ 16 c2e3jA_ 17 d2rhwa1 18 c3fsgC_ 19 d1c4xa_ 20 d2vata1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3v48B_ 100.0 98 PDB header:hydrolase Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd; PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli 2 c1cr6A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor 3 c2qmqA_ 100.0 14 PDB header:signaling protein Chain: A: PDB Molecule:protein ndrg2; PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution 4 c2r11D_ 100.0 16 PDB header:hydrolase Chain: D: PDB Molecule:carboxylesterase np; PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution 5 c2xmzA_ 100.0 14 PDB header:lyase Chain: A: PDB Molecule:hydrolase, alpha/beta hydrolase fold family; PDBTitle: structure of menh from s. aureus 6 c2wj4B_ 100.0 10 PDB header:oxidoreductase Chain: B: PDB Molecule:1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase; PDBTitle: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-2 oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter3 nitroguajacolicus ru61a anaerobically complexed with its4 natural substrate 1-h-3-hydroxy-4-oxoquinaldine 7 c2vavL_ 100.0 16 PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) 8 c3oosA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase family protein; PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne 9 c3om8A_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:probable hydrolase; PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01 10 c3qvmA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:olei00960; PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica 11 c3i1iA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis 12 c2y6vB_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) 13 c2xuaH_ 100.0 20 PDB header:hydrolase Chain: H: PDB Molecule:3-oxoadipate enol-lactonase; PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400 14 d2b61a1 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 15 c3kdaB_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:cftr inhibitory factor (cif); PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation 16 c2e3jA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase ephb; PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom 17 d2rhwa1 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 18 c3fsgC_ 100.0 13 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta superfamily hydrolase; PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1 19 d1c4xa_ 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 20 d2vata1 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 21 d1e89a_ not modelled 100.0 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 22 c3kxpD_ not modelled 100.0 17 PDB header:hydrolase Chain: D: PDB Molecule:alpha-(n-acetylaminomethylene)succinic acid PDBTitle: crystal structure of e-2-(acetamidomethylene)succinate2 hydrolase 23 d1uk8a_ not modelled 100.0 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 24 c3e3aA_ not modelled 100.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:possible peroxidase bpoc; PDBTitle: the structure of rv0554 from mycobacterium tuberculosis 25 d1b6ga_ not modelled 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 26 c1u2eA_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid PDBTitle: crystal structure of the c-c bond hydrolase mhpc 27 d1m33a_ not modelled 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Biotin biosynthesis protein BioH 28 c3ibtA_ not modelled 100.0 10 PDB header:oxidoreductase Chain: A: PDB Molecule:1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase; PDBTitle: structure of 1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase (qdo) 29 d1ehya_ not modelled 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 30 c3bwxA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase; PDBTitle: crystal structure of an alpha/beta hydrolase (yp_496220.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.50 a resolution 31 c3bf7B_ not modelled 100.0 15 PDB header:hydrolase Chain: B: PDB Molecule:esterase ybff; PDBTitle: 1.1 resolution structure of ybff, a new esterase from2 escherichia coli: a unique substrate-binding crevice3 generated by domain arrangement 32 c2cjpA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1) 33 d1xkla_ not modelled 100.0 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 34 d1zd3a2 not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 35 d1cr6a2 not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 36 c3u1tA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:dmma haloalkane dehalogenase; PDBTitle: haloalkane dehalogenase, dmma, of marine microbial origin 37 d1brta_ not modelled 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 38 c1wprA_ not modelled 100.0 17 PDB header:signaling protein Chain: A: PDB Molecule:sigma factor sigb regulation protein rsbq; PDBTitle: crystal structure of rsbq inhibited by pmsf 39 d3c70a1 not modelled 100.0 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 40 d2pl5a1 not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 41 c2pseA_ not modelled 100.0 12 PDB header:oxidoreductase Chain: A: PDB Molecule:renilla-luciferin 2-monooxygenase; PDBTitle: crystal structures of the luciferase and green fluorescent2 protein from renilla reniformis 42 c3a2nF_ not modelled 100.0 14 PDB header:hydrolase Chain: F: PDB Molecule:haloalkane dehalogenase; PDBTitle: crystal structure of dbja (wild type type ii p21) 43 c2vf2A_ not modelled 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate PDBTitle: x-ray crystal structure of hsad from mycobacterium2 tuberculosis 44 d1mtza_ not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 45 c2xt0A_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:haloalkane dehalogenase; PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i 46 c3e0xB_ not modelled 100.0 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:lipase-esterase related protein; PDBTitle: the crystal structure of a lipase-esterase related protein2 from clostridium acetobutylicum atcc 824 47 d1hkha_ not modelled 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 48 c2yysA_ not modelled 100.0 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:proline iminopeptidase-related protein; PDBTitle: crystal structure of the proline iminopeptidase-related protein2 ttha1809 from thermus thermophilus hb8 49 c3dqzB_ not modelled 100.0 13 PDB header:lyase Chain: B: PDB Molecule:alpha-hydroxynitrile lyase-like protein; PDBTitle: structure of the hydroxynitrile lyase from arabidopsis2 thaliana 50 d1a8sa_ not modelled 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 51 c1y37A_ not modelled 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:fluoroacetate dehalogenase; PDBTitle: structure of fluoroacetate dehalogenase from burkholderia sp. fa1 52 c3fobA_ not modelled 100.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:bromoperoxidase; PDBTitle: crystal structure of bromoperoxidase from bacillus anthracis 53 d1q0ra_ not modelled 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Aclacinomycin methylesterase RdmC 54 d1a8qa_ not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 55 d1va4a_ not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 56 c1zoiC_ not modelled 100.0 21 PDB header:hydrolase Chain: C: PDB Molecule:esterase; PDBTitle: crystal structure of a stereoselective esterase from2 pseudomonas putida ifo12996 57 d1bn7a_ not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 58 c3l80A_ not modelled 100.0 10 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein smu.1393c; PDBTitle: crystal structure of smu.1393c from streptococcus mutans ua159 59 d1azwa_ not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 60 c3p2mA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:possible hydrolase; PDBTitle: crystal structure of a novel esterase rv0045c from mycobacterium2 tuberculosis 61 d1j1ia_ not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 62 c1j1iA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:meta cleavage compound hydrolase; PDBTitle: crystal structure of a his-tagged serine hydrolase involved2 in the carbazole degradation (carc enzyme) 63 d1a88a_ not modelled 100.0 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 64 c3qyjB_ not modelled 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:alr0039 protein; PDBTitle: crystal structure of alr0039, a putative alpha/beta hydrolase from2 nostoc sp pcc 7120. 65 c3gzjB_ not modelled 100.0 13 PDB header:hydrolase Chain: B: PDB Molecule:polyneuridine-aldehyde esterase; PDBTitle: crystal structure of polyneuridine aldehyde esterase2 complexed with 16-epi-vellosimine 66 c3flaB_ not modelled 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:rifr; PDBTitle: rifr - type ii thioesterase from rifamycin nrps/pks biosynthetic2 pathway - form 1 67 c3r3xA_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:fluoroacetate dehalogenase; PDBTitle: crystal structure of the fluoroacetate dehalogenase rpa1163 -2 asp110asn/bromoacetate 68 d1mj5a_ not modelled 100.0 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 69 d1qo7a_ not modelled 100.0 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 70 d1wm1a_ not modelled 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 71 c3nwoA_ not modelled 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:proline iminopeptidase; PDBTitle: crystal structure of proline iminopeptidase mycobacterium smegmatis 72 c3jw8A_ not modelled 100.0 11 PDB header:hydrolase Chain: A: PDB Molecule:mgll protein; PDBTitle: crystal structure of human mono-glyceride lipase 73 d1r3da_ not modelled 100.0 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical protein VC1974 74 c3r0vA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase fold protein; PDBTitle: the crystal structure of an alpha/beta hydrolase from sphaerobacter2 thermophilus dsm 20745. 75 c2qvbA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:haloalkane dehalogenase 3; PDBTitle: crystal structure of haloalkane dehalogenase rv2579 from mycobacterium2 tuberculosis 76 d1k8qa_ not modelled 100.0 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 77 c3hjuB_ not modelled 100.0 11 PDB header:hydrolase Chain: B: PDB Molecule:monoglyceride lipase; PDBTitle: crystal structure of human monoglyceride lipase 78 d1hlga_ not modelled 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 79 c2ronA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:surfactin synthetase thioesterase subunit; PDBTitle: the external thioesterase of the surfactin-synthetase 80 c3c5wP_ not modelled 100.0 18 PDB header:hydrolase Chain: P: PDB Molecule:pp2a-specific methylesterase pme-1; PDBTitle: complex between pp2a-specific methylesterase pme-1 and pp2a core2 enzyme 81 c3qitB_ not modelled 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:polyketide synthase; PDBTitle: thioesterase domain from curacin biosynthetic pathway 82 c2ockA_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:valacyclovir hydrolase; PDBTitle: crystal structure of valacyclovir hydrolase d123n mutant 83 c3bdiA_ not modelled 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ta0194; PDBTitle: crystal structure of predicted cib-like hydrolase (np_393672.1) from2 thermoplasma acidophilum at 1.45 a resolution 84 d1tqha_ not modelled 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/lipase 85 d1imja_ not modelled 100.0 22 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Ccg1/TafII250-interacting factor B (Cib) 86 c3h04A_ not modelled 100.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50 87 c3dyvA_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:esterase d; PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism 88 c2q0xA_ not modelled 100.0 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: alpha/beta hydrolase fold protein of unknown function 89 c1pjaA_ not modelled 100.0 10 PDB header:hydrolase Chain: A: PDB Molecule:palmitoyl-protein thioesterase 2 precursor; PDBTitle: the crystal structure of palmitoyl protein thioesterase-2 reveals the2 basis for divergent substrate specificities of the two lysosomal3 thioesterases (ppt1 and ppt2) 90 d1pjaa_ not modelled 100.0 10 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterases 91 c3llcA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution 92 c3qmwD_ not modelled 100.0 19 PDB header:hydrolase Chain: D: PDB Molecule:thioesterase; PDBTitle: redj with peg molecule bound in the active site 93 c3ilsA_ not modelled 100.0 10 PDB header:hydrolase Chain: A: PDB Molecule:aflatoxin biosynthesis polyketide synthase; PDBTitle: the thioesterase domain from pksa 94 c3qm1A_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:cinnamoyl esterase; PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii 95 d1xkta_ not modelled 100.0 12 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 96 c3lcrA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:tautomycetin biosynthetic pks; PDBTitle: thioesterase from tautomycetin biosynthhetic pathway 97 c2wtmC_ not modelled 99.9 17 PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus 98 c3fleB_ not modelled 99.9 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:se_1780 protein; PDBTitle: se_1780 protein of unknown function from staphylococcus epidermidis. 99 c3fcyB_ not modelled 99.9 13 PDB header:hydrolase Chain: B: PDB Molecule:xylan esterase 1; PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485 100 d1l7aa_ not modelled 99.9 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetyl xylan esterase-like 101 c2hdwB_ not modelled 99.9 12 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein pa2218; PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa 102 c2px6A_ not modelled 99.9 13 PDB header:transferase Chain: A: PDB Molecule:thioesterase domain; PDBTitle: crystal structure of the thioesterase domain of human fatty2 acid synthase inhibited by orlistat 103 c2h7xA_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:type i polyketide synthase pikaiv; PDBTitle: pikromycin thioesterase adduct with reduced triketide2 affinity label 104 d2h7xa1 not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 105 d1qlwa_ not modelled 99.9 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:A novel bacterial esterase 106 c3fnbB_ not modelled 99.9 14 PDB header:hydrolase Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737; PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159 107 d1ex9a_ not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 108 c2jbwB_ not modelled 99.9 17 PDB header:hydrolase Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase; PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase. 109 c2qruA_ not modelled 99.9 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis 110 c2rauA_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:putative esterase; PDBTitle: crystal structure of a putative lipase (np_343859.1) from sulfolobus2 solfataricus at 1.85 a resolution 111 d1ufoa_ not modelled 99.9 21 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical protein TT1662 112 c3mveB_ not modelled 99.9 11 PDB header:lyase Chain: B: PDB Molecule:upf0255 protein vv1_0328; PDBTitle: crystal structure of a novel pyruvate decarboxylase 113 c3ksrA_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:putative serine hydrolase; PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution 114 d2jbwa1 not modelled 99.9 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:2,6-dihydropseudooxynicotine hydrolase-like 115 c1mo2A_ not modelled 99.9 14 PDB header:transferase Chain: A: PDB Molecule:erythronolide synthase, modules 5 and 6; PDBTitle: thioesterase domain from 6-deoxyerythronolide synthase2 (debs te), ph 8.5 116 d1mo2a_ not modelled 99.9 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 117 d1uxoa_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:YdeN-like 118 d1ispa_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Bacterial lipase 119 c2qs9A_ not modelled 99.9 17 PDB header:structural protein Chain: A: PDB Molecule:retinoblastoma-binding protein 9; PDBTitle: crystal structure of the human retinoblastoma-binding2 protein 9 (rbbp-9). nesg target hr2978 120 c3lp5A_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:putative cell surface hydrolase; PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0