BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (136 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q48DU1 Large-conductance mechanosensitive channel n=45 ...   188   5e-47
UniRef50_C4K3W6 Mechanosensitive channel n=1 Tax=Candidatus Hami...   170   1e-41
UniRef50_B4S9H4 Large-conductance mechanosensitive channel n=23 ...   167   1e-40
UniRef50_Q2NQQ0 Large-conductance mechanosensitive channel n=18 ...   161   5e-39
UniRef50_A7GXI2 Large-conductance mechanosensitive channel n=4 T...   159   3e-38
UniRef50_A6L685 Large-conductance mechanosensitive channel n=58 ...   156   2e-37
UniRef50_A7I339 Large-conductance mechanosensitive channel n=28 ...   156   2e-37
UniRef50_Q5LGV7 Large-conductance mechanosensitive channel n=20 ...   151   7e-36
UniRef50_A4IMP7 Large-conductance mechanosensitive channel n=13 ...   147   1e-34
UniRef50_Q89ZV7 Large-conductance mechanosensitive channel n=9 T...   146   2e-34
UniRef50_A0Q171 Large conductance mechanosensitive channel prote...   146   3e-34
UniRef50_B4RCK7 Large-conductance mechanosensitive channel n=31 ...   145   4e-34
UniRef50_C3WUH2 Large-conductance mechanosensitive channel n=5 T...   142   4e-33
UniRef50_C3J8B0 Large conductance mechanosensitive channel prote...   140   1e-32
UniRef50_D2EUH9 Large conductance mechanosensitive channel prote...   140   1e-32
UniRef50_Q2JLN5 Large-conductance mechanosensitive channel n=3 T...   133   2e-30
UniRef50_D2QT75 Large conductance mechanosensitive channel prote...   132   3e-30
UniRef50_A9VKI1 Large-conductance mechanosensitive channel n=72 ...   131   5e-30
UniRef50_Q3ANR9 Large-conductance mechanosensitive channel n=24 ...   130   9e-30
UniRef50_C7JGJ5 Large-conductance mechanosensitive channel n=9 T...   127   1e-28
UniRef50_B8G6C2 Large-conductance mechanosensitive channel n=7 T...   123   2e-27
UniRef50_A6WVY7 Large-conductance mechanosensitive channel n=26 ...   123   2e-27
UniRef50_A3MKN7 Large-conductance mechanosensitive channel n=286...   122   4e-27
UniRef50_Q1LIC3 Large-conductance mechanosensitive channel n=26 ...   122   5e-27
UniRef50_Q3B3W2 Large-conductance mechanosensitive channel n=20 ...   117   1e-25
UniRef50_Q2G9Z8 Large-conductance mechanosensitive channel n=3 T...   116   2e-25
UniRef50_C9LNV3 Large conductance mechanosensitive channel prote...   115   3e-25
UniRef50_A0M1G0 Large-conductance mechanosensitive channel n=10 ...   115   3e-25
UniRef50_C0Z921 Large-conductance mechanosensitive channel n=36 ...   115   4e-25
UniRef50_A2TYX0 Large-conductance mechanosensitive channel n=1 T...   114   9e-25
UniRef50_A1B4B3 Large-conductance mechanosensitive channel n=45 ...   113   2e-24
UniRef50_B1YKK2 Large-conductance mechanosensitive channel n=2 T...   110   1e-23
UniRef50_A4CIE9 Large-conductance mechanosensitive channel n=7 T...   109   2e-23
UniRef50_A7X204 Large-conductance mechanosensitive channel n=51 ...   109   3e-23
UniRef50_Q6MD32 Putative mechanosensitive channel of large condu...   107   8e-23
UniRef50_D2LWQ6 Large conductance mechanosensitive channel prote...   107   1e-22
UniRef50_UPI000196C3D3 hypothetical protein CATMIT_02956 n=1 Tax...   107   1e-22
UniRef50_D2R1B6 Large conductance mechanosensitive channel prote...   105   3e-22
UniRef50_UPI0001C42BC0 large-conductance mechanosensitive channe...   105   4e-22
UniRef50_Q034S0 Large-conductance mechanosensitive channel n=4 T...   105   4e-22
UniRef50_C7MN86 Large conductance mechanosensitive channel prote...   104   8e-22
UniRef50_Q7UW50 Probable large-conductance mechanosensitive chan...   104   8e-22
UniRef50_A6M387 Large-conductance mechanosensitive channel n=7 T...   103   1e-21
UniRef50_A4CLF8 Large conductance mechanosensitive channel prote...   103   1e-21
UniRef50_UPI0000DB7E8B PREDICTED: hypothetical protein, partial ...   101   7e-21
UniRef50_Q03D91 Large-conductance mechanosensitive channel n=16 ...   100   1e-20
UniRef50_Q1QDU6 Large-conductance mechanosensitive channel n=5 T...    99   4e-20
UniRef50_Q5NNP2 Large-conductance mechanosensitive channel n=5 T...    97   1e-19
UniRef50_B0T274 Large-conductance mechanosensitive channel n=42 ...    97   2e-19
UniRef50_B2GJ27 Large-conductance mechanosensitive channel n=5 T...    96   5e-19
UniRef50_C0QYW6 Large-conductance mechanosensitive channel n=2 T...    94   9e-19
UniRef50_A9HW97 Large-conductance mechanosensitive channel n=98 ...    94   1e-18
UniRef50_C6XFL7 Large conductance mechanosensitive channel prote...    94   1e-18
UniRef50_Q2JGX8 Large conductance mechanosensitive channel prote...    93   3e-18
UniRef50_C9RJE4 Large conductance mechanosensitive channel prote...    92   3e-18
UniRef50_D2MPY5 Large conductance mechanosensitive channel prote...    92   4e-18
UniRef50_C8NCV5 Large conductance mechanosensitive channel prote...    92   4e-18
UniRef50_B0K2H2 Large conductance mechanosensitive channel prote...    92   5e-18
UniRef50_C1XQ99 Large conductance mechanosensitive channel prote...    91   8e-18
UniRef50_D1BNK2 Large conductance mechanosensitive channel prote...    89   4e-17
UniRef50_D1AZE9 Large conductance mechanosensitive channel prote...    89   6e-17
UniRef50_Q2N8W2 Mechanosensitive channel n=1 Tax=Erythrobacter l...    87   1e-16
UniRef50_C5BF23 Putative uncharacterized protein n=1 Tax=Edwards...    87   1e-16
UniRef50_B1V916 Putative large-conductance mechanosensitive chan...    87   2e-16
UniRef50_Q31LP8 Large-conductance mechanosensitive channel n=2 T...    86   3e-16
UniRef50_A9WMF7 Large-conductance mechanosensitive channel n=2 T...    86   3e-16
UniRef50_Q04FK1 Large-conductance mechanosensitive channel n=4 T...    85   6e-16
UniRef50_B1XK85 Large conductance mechanosensitive channel prote...    85   7e-16
UniRef50_C6WJF5 Large conductance mechanosensitive channel prote...    85   8e-16
UniRef50_Q2NK99 Large-conductance mechanosensitive channel n=2 T...    85   9e-16
UniRef50_C5RAB3 MscL family large conductance mechanosensitive i...    84   1e-15
UniRef50_C2BQ59 MscL family large conductance mechanosensitive i...    81   8e-15
UniRef50_Q5HPJ2 Large-conductance mechanosensitive channel n=9 T...    81   8e-15
UniRef50_C0WF41 MscL family large conductance mechanosensitive i...    81   9e-15
UniRef50_B0S3E4 Large-conductive mechanosensitive channel n=2 Ta...    81   1e-14
UniRef50_A9KIC1 Large conductance mechanosensitive channel prote...    81   1e-14
UniRef50_A3CM47 Large conductance mechano-sensitive ion channel,...    81   1e-14
UniRef50_C7H9Q8 Large conductance mechanosensitive channel prote...    79   3e-14
UniRef50_A5UVR8 Large-conductance mechanosensitive channel n=2 T...    79   4e-14
UniRef50_B2IVG3 Large conductance mechanosensitive channel prote...    79   4e-14
UniRef50_Q8DHB2 Large-conductive mechanosensitive channel n=1 Ta...    79   4e-14
UniRef50_C8W9F9 Large conductance mechanosensitive channel prote...    79   5e-14
UniRef50_A7VB12 Putative uncharacterized protein n=1 Tax=Clostri...    79   5e-14
UniRef50_Q82ZB4 Large-conductance mechanosensitive channel n=40 ...    78   8e-14
UniRef50_A7B9R5 Putative uncharacterized protein n=1 Tax=Actinom...    78   1e-13
UniRef50_B9CMP0 Large conductance mechanosensitive channel prote...    77   1e-13
UniRef50_A6W442 Large conductance mechanosensitive channel prote...    77   1e-13
UniRef50_Q6AGE6 Large-conductance mechanosensitive channel n=7 T...    77   2e-13
UniRef50_Q98B35 Large-conductance mechanosensitive channel n=1 T...    77   2e-13
UniRef50_C5BZI9 Large conductance mechanosensitive channel prote...    77   2e-13
UniRef50_B4D701 Large conductance mechanosensitive channel prote...    77   2e-13
UniRef50_D1BCH3 Large conductance mechanosensitive channel prote...    77   2e-13
UniRef50_A4AI90 Large-conductance mechanosensitive channel n=1 T...    77   2e-13
UniRef50_C7HUU0 Large conductance mechanosensitive channel prote...    77   2e-13
UniRef50_A8LHK6 Large conductance mechanosensitive channel prote...    76   4e-13
UniRef50_C8WNX6 Large conductance mechanosensitive channel prote...    75   7e-13
UniRef50_Q9RRR4 Large conductance mechanosensitive channel n=1 T...    74   1e-12
UniRef50_Q6AAH3 Large conductance mechanosensitive channel n=4 T...    74   2e-12
UniRef50_A6GYI6 Large-conductance mechanosensitive channel n=4 T...    74   2e-12
UniRef50_UPI000050F91C putative large-conductance mechanosensiti...    73   3e-12
UniRef50_Q025U4 Large conductance mechanosensitive channel prote...    72   5e-12
UniRef50_C4FVI2 Putative uncharacterized protein n=1 Tax=Catonel...    71   8e-12
UniRef50_A0JZ24 Large conductance mechanosensitive channel prote...    71   1e-11
UniRef50_C6R3M2 Large conductance mechanosensitive channel prote...    70   2e-11
UniRef50_C4FGI6 Putative uncharacterized protein n=1 Tax=Bifidob...    70   3e-11
UniRef50_D0WJR5 Large conductance mechanosensitive channel prote...    70   3e-11
UniRef50_B3QZY1 Large-conductance mechanosensitive channel n=1 T...    70   3e-11
UniRef50_C1RGF4 Large conductance mechanosensitive channel prote...    69   5e-11
UniRef50_C4LHF9 Transport protein of the large conductance mecha...    68   8e-11
UniRef50_D2B464 Large conductance mechanosensitive channel prote...    68   8e-11
UniRef50_Q8EW76 Large-conductance mechanosensitive channel n=1 T...    67   1e-10
UniRef50_D0P2C5 Large Conductance Mechanosensitive Ion Channel (...    67   2e-10
UniRef50_Q6KH26 Large-conductance mechanosensitive channel n=1 T...    67   3e-10
UniRef50_B5Y8I7 Large conductance mechanosensitive channel prote...    66   3e-10
UniRef50_A7HBZ5 Large conductance mechanosensitive channel prote...    66   3e-10
UniRef50_B4V9Z0 Mechanosensitive channel n=3 Tax=Streptomyces Re...    65   5e-10
UniRef50_P73553 Large-conductance mechanosensitive channel n=2 T...    65   7e-10
UniRef50_B3DRI7 Large-conductance mechanosensitive channel n=17 ...    65   8e-10
UniRef50_C7MC43 Large conductance mechanosensitive channel prote...    65   1e-09
UniRef50_Q5SKL6 Large-conductance mechanosensitive channel n=2 T...    64   1e-09
UniRef50_B3PMZ4 Large-conductance mechanosensitive channel, puta...    64   1e-09
UniRef50_B5GFS7 Mechanosensitive channel n=12 Tax=Streptomyces R...    64   2e-09
UniRef50_B8DV17 Large conductance mechanosensitive channel prote...    63   3e-09
UniRef50_D2S4B1 Large conductance mechanosensitive channel prote...    62   5e-09
UniRef50_C7QC56 Large conductance mechanosensitive channel prote...    61   9e-09
UniRef50_A5Z9U3 Putative uncharacterized protein n=1 Tax=Eubacte...    61   1e-08
UniRef50_Q9P639 Related to large-conductance mechanosensitive ch...    61   1e-08
UniRef50_B8MJW8 Ion channel, putative n=3 Tax=Trichocomaceae Rep...    61   1e-08
UniRef50_Q82H65 Putative mechanosensitive channel n=2 Tax=Strept...    61   1e-08
UniRef50_A4RKI5 Putative uncharacterized protein n=1 Tax=Magnapo...    60   2e-08
UniRef50_D0L6D3 Large conductance mechanosensitive channel prote...    60   2e-08
UniRef50_A5KRR6 Large-conductance mechanosensitive channel-like ...    60   2e-08
UniRef50_A1RBS3 Large conductance mechanosensitive channel prote...    59   4e-08
UniRef50_D1YYF3 Putative large-conductance mechanosensitive chan...    58   8e-08
UniRef50_B8ZU13 Large-conductance mechanosensitive channel n=23 ...    56   3e-07
UniRef50_Q3D697 Large conductance mechanosensitive channel prote...    56   3e-07
UniRef50_B4WRC7 Large conductance mechanosensitive channel prote...    54   1e-06
UniRef50_Q0IDN4 Large conductance mechanosensitive channel prote...    54   1e-06
UniRef50_B8MKR4 Large-conductance mechanosensitive channel, puta...    53   3e-06
UniRef50_A5GNA8 Large-conductance mechanosensitive channel n=1 T...    53   3e-06
UniRef50_A5IYZ8 Large conductance mechanosensitive channel n=1 T...    52   5e-06
UniRef50_D2ARQ8 Large conductance mechanosensitive channel prote...    52   6e-06
UniRef50_A3Z5P9 Possible large-conductance mechanosensitive chan...    52   6e-06
UniRef50_B6HL82 Pc21g07880 protein n=6 Tax=Trichocomaceae RepID=...    52   7e-06
UniRef50_B2VVD2 Putative uncharacterized protein n=1 Tax=Pyrenop...    51   1e-05
UniRef50_Q0CER3 Putative uncharacterized protein n=3 Tax=Aspergi...    50   2e-05
UniRef50_A8N9V8 Putative uncharacterized protein n=1 Tax=Coprino...    50   3e-05
UniRef50_C9S828 Putative uncharacterized protein n=1 Tax=Vertici...    49   4e-05
UniRef50_UPI00017434B6 large conductance mechanosensitive channe...    49   6e-05
UniRef50_D0P2C6 Large conductance mechanosensitive channel, puta...    48   8e-05
UniRef50_Q0I7U4 Large-conductive mechanosensitive channel n=2 Ta...    48   9e-05
UniRef50_C7PYG5 Large conductance mechanosensitive channel prote...    48   1e-04
UniRef50_A7I494 Large-conductance mechanosensitive channel-like ...    47   2e-04
UniRef50_A4F7T6 Large-conductance mechanosensitive channel n=3 T...    46   3e-04
UniRef50_Q2FQE0 Large conductance mechanosensitive channel prote...    46   3e-04
UniRef50_Q2IFL2 Large-conductance mechanosensitive channel-like ...    46   3e-04
UniRef50_D1J7K2 Large-conductance mechanosensitive channel n=1 T...    46   4e-04
UniRef50_A5GSN0 Large-conductance mechanosensitive channel n=1 T...    45   7e-04
UniRef50_UPI00016B2696 Large-conductance mechanosensitive channe...    45   9e-04
UniRef50_C1AX17 Large-conductance mechanosensitive channel n=2 T...    44   0.001
UniRef50_UPI0001B45932 large conductance mechanosensitive channe...    44   0.002
UniRef50_A7HMH6 Putative uncharacterized protein n=1 Tax=Fervido...    41   0.010
UniRef50_Q83MR6 Large-conductance mechanosensitive channel n=2 T...    39   0.037
UniRef50_Q3AHC1 Large-conductive mechanosensitive channel n=1 Ta...    39   0.038
UniRef50_A1SES5 Large-conductance mechanosensitive channel n=1 T...    39   0.053

>UniRef50_Q48DU1 Large-conductance mechanosensitive channel n=45 Tax=Bacteria
           RepID=MSCL_PSE14
          Length = 148

 Score =  188 bits (477), Expect = 5e-47,   Method: Compositional matrix adjust.
 Identities = 90/135 (66%), Positives = 111/135 (82%), Gaps = 1/135 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS++ EF+ FA++GNVVD+AVG+IIGAAFGKIVSS V D+IMPPLGLLIGG+DF   A+T
Sbjct: 1   MSVLSEFKAFAVKGNVVDMAVGIIIGAAFGKIVSSFVGDVIMPPLGLLIGGVDFSDLAIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK-EEPAAAPAPTKEE 119
           LR AQG  PAV++ YG FIQ V DF+IVAFAIFM +K IN+L R++ + P   P P+K+E
Sbjct: 61  LRPAQGTAPAVLLAYGKFIQTVIDFIIVAFAIFMGVKAINRLKREEAKAPTLPPTPSKQE 120

Query: 120 VLLTEIRDLLKEQNN 134
           VLL+EIRDLLKEQN 
Sbjct: 121 VLLSEIRDLLKEQNK 135


>UniRef50_C4K3W6 Mechanosensitive channel n=1 Tax=Candidatus Hamiltonella defensa
           5AT (Acyrthosiphon pisum) RepID=C4K3W6_HAMD5
          Length = 150

 Score =  170 bits (430), Expect = 1e-41,   Method: Compositional matrix adjust.
 Identities = 86/150 (57%), Positives = 106/150 (70%), Gaps = 15/150 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS IKEFREFAMRGNV DLA+GVIIG+AFGK+VSSLVADIIMPP+GLLIGG+D KQF+  
Sbjct: 1   MSFIKEFREFAMRGNVADLAIGVIIGSAFGKVVSSLVADIIMPPIGLLIGGVDLKQFSFV 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR---------------K 105
           LR+A+ D+PAV+M+YG F+Q++ D +IV  AIF  IK +NKL R               K
Sbjct: 61  LREARNDVPAVIMNYGSFLQSLVDCIIVTLAIFSVIKFMNKLRRELEGILESRAEINKEK 120

Query: 106 KEEPAAAPAPTKEEVLLTEIRDLLKEQNNR 135
            E       P  +E+LL EIRDLLK+   +
Sbjct: 121 TEVGTQVEPPAPQEILLMEIRDLLKKSTKK 150


>UniRef50_B4S9H4 Large-conductance mechanosensitive channel n=23 Tax=Bacteria
           RepID=MSCL_PROA2
          Length = 134

 Score =  167 bits (423), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 81/134 (60%), Positives = 105/134 (78%), Gaps = 1/134 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M  I+EF++FAMRGNVVDLAVG+IIG AFGK+V++LV  ++MPP+GLLIGG++F Q A  
Sbjct: 1   MGFIQEFKDFAMRGNVVDLAVGIIIGGAFGKVVTALVDGVLMPPIGLLIGGVNFDQLAFE 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-PAAAPAPTKEE 119
           LR A  +  AV ++YG F+Q + DF+I+AF+IF+ IK +N L RK EE P A P P+KEE
Sbjct: 61  LRAATAESAAVSLNYGAFLQTIVDFVIIAFSIFVVIKALNSLKRKSEEAPKAPPVPSKEE 120

Query: 120 VLLTEIRDLLKEQN 133
           VLL EIRDLLKE+ 
Sbjct: 121 VLLGEIRDLLKERG 134


>UniRef50_Q2NQQ0 Large-conductance mechanosensitive channel n=18
           Tax=Gammaproteobacteria RepID=MSCL_SODGM
          Length = 144

 Score =  161 bits (408), Expect = 5e-39,   Method: Compositional matrix adjust.
 Identities = 77/101 (76%), Positives = 92/101 (91%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS +++FR+FAMRGNVVDLAVG+IIGAAFGKIVSSLVA++IMP LGLLIGGIDFKQF+  
Sbjct: 1   MSFLQKFRKFAMRGNVVDLAVGIIIGAAFGKIVSSLVANVIMPQLGLLIGGIDFKQFSWV 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
           L+ AQGD PAVVM YG+F+QN+FDF+IVAFA+F  IKLIN+
Sbjct: 61  LKPAQGDTPAVVMKYGIFLQNIFDFIIVAFAVFCIIKLINR 101


>UniRef50_A7GXI2 Large-conductance mechanosensitive channel n=4 Tax=Bacteria
           RepID=MSCL_CAMC5
          Length = 133

 Score =  159 bits (401), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 80/133 (60%), Positives = 100/133 (75%), Gaps = 2/133 (1%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS I EF+EFAM+GNV+D+AVGV+IG AFGKIVSSLV DIIMP +G++ GG++F    +T
Sbjct: 1   MSFIGEFKEFAMKGNVLDMAVGVVIGTAFGKIVSSLVGDIIMPIVGVITGGVNFTDLKIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAA--PAPTKE 118
           L+DA   +PAV ++YG FIQ   DFLI+AF IF  IK IN L RK  EP  A   AP ++
Sbjct: 61  LKDAAQGVPAVTINYGNFIQTAVDFLIIAFCIFCVIKAINSLKRKPAEPEVAQPAAPAED 120

Query: 119 EVLLTEIRDLLKE 131
            VLLT+IRDLLK+
Sbjct: 121 IVLLTQIRDLLKK 133


>UniRef50_A6L685 Large-conductance mechanosensitive channel n=58 Tax=Bacteria
           RepID=MSCL_BACV8
          Length = 146

 Score =  156 bits (395), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 86/141 (60%), Positives = 113/141 (80%), Gaps = 7/141 (4%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S +++F+ FAMRGNV+D+AVGVIIG AFGKIVSS+VAD+IMPP+GLL+GG++F    + L
Sbjct: 5   SFLQDFKAFAMRGNVIDMAVGVIIGGAFGKIVSSIVADVIMPPIGLLVGGVNFTDLKLQL 64

Query: 62  RDAQ----GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE---PAAAPA 114
           + A+     +  AV ++YG F+Q  FDF+I+AF+IF+ I+L+ KLNRKKEE   PAA PA
Sbjct: 65  KPAEVVDGVEKAAVTLNYGNFLQATFDFIIIAFSIFLFIRLLAKLNRKKEEVPAPAAPPA 124

Query: 115 PTKEEVLLTEIRDLLKEQNNR 135
           P+KEEVLLTEIRDLLKEQ  +
Sbjct: 125 PSKEEVLLTEIRDLLKEQAGK 145


>UniRef50_A7I339 Large-conductance mechanosensitive channel n=28 Tax=Bacteria
           RepID=MSCL_CAMHC
          Length = 132

 Score =  156 bits (394), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 77/132 (58%), Positives = 104/132 (78%), Gaps = 1/132 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS IKEF+EFA++GNV+D+AVGV+IG+AFGKIVSSLV D+IMP +G+L GG++F    +T
Sbjct: 1   MSFIKEFKEFAVKGNVIDMAVGVVIGSAFGKIVSSLVGDVIMPVVGVLTGGVNFTDLKIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR-KKEEPAAAPAPTKEE 119
           +++A G+  AV ++YG FIQ   DFLI+AF IF+AIK IN+L + +K+EP A   P  E 
Sbjct: 61  IKEAVGENAAVTINYGNFIQVTIDFLIIAFCIFLAIKAINQLKKPEKQEPKAPAEPNDEV 120

Query: 120 VLLTEIRDLLKE 131
            LL+EIRDLLK+
Sbjct: 121 KLLSEIRDLLKK 132


>UniRef50_Q5LGV7 Large-conductance mechanosensitive channel n=20 Tax=Bacteria
           RepID=MSCL_BACFN
          Length = 146

 Score =  151 bits (381), Expect = 7e-36,   Method: Compositional matrix adjust.
 Identities = 84/142 (59%), Positives = 106/142 (74%), Gaps = 10/142 (7%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + +++F+ FAM+GNVVD+AVGVIIG AFGKIVSS+VADIIMPPLGLLIGG++F      +
Sbjct: 5   TFLQDFKAFAMKGNVVDMAVGVIIGGAFGKIVSSVVADIIMPPLGLLIGGVNFTDLKWVM 64

Query: 62  R------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK----EEPAA 111
           +      D +    AV ++YG F+Q  FDFLI+AF+IF+ IKLI KL +KK      P A
Sbjct: 65  KAAEYGADGKETAAAVTLNYGNFLQATFDFLIIAFSIFLFIKLITKLTQKKAEAPAAPPA 124

Query: 112 APAPTKEEVLLTEIRDLLKEQN 133
            PAPTKEE+LLTEIRDLLKE+ 
Sbjct: 125 PPAPTKEEILLTEIRDLLKEKQ 146


>UniRef50_A4IMP7 Large-conductance mechanosensitive channel n=13 Tax=Bacteria
           RepID=MSCL_GEOTN
          Length = 131

 Score =  147 bits (371), Expect = 1e-34,   Method: Compositional matrix adjust.
 Identities = 79/131 (60%), Positives = 96/131 (73%), Gaps = 11/131 (8%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           EF++FA+RGNV+DLAVGVIIG AFGKIVSSLV DIIMP +GLL+GGIDF   +  +  A 
Sbjct: 4   EFKKFAIRGNVIDLAVGVIIGGAFGKIVSSLVNDIIMPLVGLLLGGIDFSNLSWKVGKA- 62

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL----NRKKEEPAAAPAPTKEEVL 121
                 V+ YG FIQ V DFLI+AF+IF+ +KLINKL     +++E     P  TKEE L
Sbjct: 63  ------VVKYGAFIQTVVDFLIIAFSIFLFVKLINKLYERVKKQEEMEETEPTLTKEEEL 116

Query: 122 LTEIRDLLKEQ 132
           LTEIRDLLK+Q
Sbjct: 117 LTEIRDLLKQQ 127


>UniRef50_Q89ZV7 Large-conductance mechanosensitive channel n=9 Tax=Bacteria
           RepID=MSCL_BACTN
          Length = 148

 Score =  146 bits (368), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 81/144 (56%), Positives = 105/144 (72%), Gaps = 12/144 (8%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + +++F+ FAM+GNV+D+AVGV+IG AFGKIVSSLVA++IMPP+GLL+GG++F      +
Sbjct: 5   TFLQDFKAFAMKGNVIDMAVGVVIGGAFGKIVSSLVANVIMPPIGLLVGGVNFTDLKWVM 64

Query: 62  R------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK------EEP 109
           +      D +   PAV + YG F+Q  FDFLI+AFAIF+ I+LI KL  KK        P
Sbjct: 65  KAAEVGADGKEIAPAVSLDYGQFLQATFDFLIIAFAIFLFIRLITKLTTKKAAEEAPAAP 124

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQN 133
            A PAPTKEEVLLTEIRDLLKE+ 
Sbjct: 125 PAPPAPTKEEVLLTEIRDLLKEKK 148


>UniRef50_A0Q171 Large conductance mechanosensitive channel protein n=6
           Tax=Clostridium RepID=A0Q171_CLONN
          Length = 138

 Score =  146 bits (368), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 77/133 (57%), Positives = 100/133 (75%), Gaps = 3/133 (2%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           IKEF+EFAM+GNV+DLAVGV+IG AFGKIVSSLV D+IMP +GL+ GGI+F    +TL+ 
Sbjct: 5   IKEFKEFAMKGNVLDLAVGVVIGGAFGKIVSSLVKDVIMPIIGLITGGINFTYLKITLKH 64

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN---RKKEEPAAAPAPTKEEV 120
             G+ P + ++ G FIQNV DF+I+AF+IFM IKLI+KL     ++E+      P+ E V
Sbjct: 65  GIGNKPPITLNIGNFIQNVVDFIIIAFSIFMFIKLISKLQIKKVEEEKEKEEETPSDEVV 124

Query: 121 LLTEIRDLLKEQN 133
           LL EIRDLLK+ N
Sbjct: 125 LLQEIRDLLKKDN 137


>UniRef50_B4RCK7 Large-conductance mechanosensitive channel n=31 Tax=Bacteria
           RepID=MSCL_PHEZH
          Length = 139

 Score =  145 bits (366), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 76/139 (54%), Positives = 95/139 (68%), Gaps = 5/139 (3%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSII EFREF  RGNV+DLAVGVIIGAAF  IV +LV +I+MPP+GL++ GIDF   A  
Sbjct: 1   MSIISEFREFIARGNVIDLAVGVIIGAAFNDIVKALVDNIVMPPIGLVLSGIDFSDLAWV 60

Query: 61  LRDAQGDIP---AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE--PAAAPAP 115
           L+      P   AV + YG FI     FLIVA+A+FM +KL+N + R++ E  P   PAP
Sbjct: 61  LKPDDPATPALDAVAIQYGAFINTCIRFLIVAWAVFMLVKLVNVIRRREAEKPPEEKPAP 120

Query: 116 TKEEVLLTEIRDLLKEQNN 134
           T +E LL EIRDLLK + +
Sbjct: 121 TPQETLLMEIRDLLKRRAD 139


>UniRef50_C3WUH2 Large-conductance mechanosensitive channel n=5 Tax=Fusobacterium
           RepID=C3WUH2_9FUSO
          Length = 137

 Score =  142 bits (357), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 73/135 (54%), Positives = 94/135 (69%), Gaps = 1/135 (0%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            +++EF+ F MRGNVVD+AVGVII  AFGKIV+SLV DI MP +G LIG ++F    + L
Sbjct: 3   KLLEEFKAFVMRGNVVDMAVGVIIATAFGKIVASLVNDIFMPIIGALIGNMNFSDLQIKL 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-PAAAPAPTKEEV 120
                 +    + YG FIQ V +FLI+AF IF+ IK++  L +KKEE PA AP PTKEEV
Sbjct: 63  GTPVEGVEQAAIRYGAFIQEVINFLIIAFCIFVFIKVVTSLQKKKEEKPAPAPEPTKEEV 122

Query: 121 LLTEIRDLLKEQNNR 135
           LLTEIRD L +  ++
Sbjct: 123 LLTEIRDALNKMADK 137


>UniRef50_C3J8B0 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C3J8B0_9PORP
          Length = 142

 Score =  140 bits (353), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 76/139 (54%), Positives = 97/139 (69%), Gaps = 6/139 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++ EF+EFAMRGNV+D+AVG+IIG AFGKIVSSLVAD+IMPP+ LL  G + +     LR
Sbjct: 4   LVSEFKEFAMRGNVMDMAVGIIIGGAFGKIVSSLVADVIMPPITLLTSGSNIEDLKWVLR 63

Query: 63  DA---QGDI--PAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK-EEPAAAPAPT 116
           +A    G+I  P V M  G F+Q V DF I+AF IFM IK +NKL + K EEPA    P+
Sbjct: 64  EAVIEGGEITRPEVAMTVGTFLQAVLDFFIIAFVIFMLIKGMNKLRKAKPEEPATPAEPS 123

Query: 117 KEEVLLTEIRDLLKEQNNR 135
            E  LL EI++LLK+Q  +
Sbjct: 124 DEVKLLGEIKELLKKQAEK 142


>UniRef50_D2EUH9 Large conductance mechanosensitive channel protein n=8
           Tax=Bacteroidales RepID=D2EUH9_9BACE
          Length = 144

 Score =  140 bits (353), Expect = 1e-32,   Method: Compositional matrix adjust.
 Identities = 82/140 (58%), Positives = 105/140 (75%), Gaps = 9/140 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S ++EF+ FAM+GNV+D+AVGVIIG AFGKIVSS+VAD+IMPP+GLL+GG++F      L
Sbjct: 5   SFLQEFKAFAMKGNVIDMAVGVIIGGAFGKIVSSIVADVIMPPIGLLVGGVNFTDLKWVL 64

Query: 62  RDAQ----GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN-----RKKEEPAAA 112
           + A+     +I AV ++YG F+Q  FDFLI+AF+IFM IKL+ KL           P A 
Sbjct: 65  KPAEMVDGKEIAAVTLNYGNFLQVTFDFLIIAFSIFMFIKLLTKLTEKKKEEAPAAPPAP 124

Query: 113 PAPTKEEVLLTEIRDLLKEQ 132
           PAP+KEEVLLTEIRDLLKE+
Sbjct: 125 PAPSKEEVLLTEIRDLLKEK 144


>UniRef50_Q2JLN5 Large-conductance mechanosensitive channel n=3 Tax=Bacteria
           RepID=MSCL_SYNJB
          Length = 132

 Score =  133 bits (334), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 70/134 (52%), Positives = 94/134 (70%), Gaps = 5/134 (3%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + ++EF+ F  RGN +DLAVGV+IG AFGKIV+S VAD+  P LGL+IGG++F+  A  +
Sbjct: 3   AFLEEFKNFISRGNALDLAVGVVIGGAFGKIVTSFVADLFTPVLGLMIGGVNFQHLAWEI 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-PAAAPAPTKEEV 120
             +  D   V ++YG F+Q VFDF+I+AFAIF+ +K IN L RK+EE P   P P  E V
Sbjct: 63  GGSPED--PVTINYGSFLQAVFDFVIIAFAIFLLVKAINTLQRKEEESPPTLPPP--EVV 118

Query: 121 LLTEIRDLLKEQNN 134
           LLTEIRD+L   + 
Sbjct: 119 LLTEIRDILNRHSQ 132


>UniRef50_D2QT75 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=D2QT75_9SPHI
          Length = 163

 Score =  132 bits (333), Expect = 3e-30,   Method: Compositional matrix adjust.
 Identities = 75/141 (53%), Positives = 95/141 (67%), Gaps = 9/141 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFAMRGNV+DLAVGVIIGAAFGKIV S+V D+IMP +G+++G +DF    V L 
Sbjct: 1   MLKEFKEFAMRGNVMDLAVGVIIGAAFGKIVDSVVNDLIMPLVGMVVGNVDFSNLYVPLS 60

Query: 63  D--------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA-AAP 113
           D        A       V  YG F+  V DFLI+AF IF+ I+ +N+L R K +     P
Sbjct: 61  DKITPGLALADARKLGPVFAYGSFLTIVIDFLILAFIIFLLIRGMNRLMRAKADTVDIPP 120

Query: 114 APTKEEVLLTEIRDLLKEQNN 134
           APTKEEVLLTEIRD L   ++
Sbjct: 121 APTKEEVLLTEIRDALVASSS 141


>UniRef50_A9VKI1 Large-conductance mechanosensitive channel n=72 Tax=Bacillus
           RepID=MSCL_BACWK
          Length = 133

 Score =  131 bits (330), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 73/132 (55%), Positives = 95/132 (71%), Gaps = 10/132 (7%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           EF++FA +GNV+DLAVGV+IGAAFGKIVSSLV DII P LG+++GG++F    +T   + 
Sbjct: 4   EFKKFAFKGNVIDLAVGVVIGAAFGKIVSSLVKDIITPLLGMVLGGVNFTDLKLTFGKSS 63

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK---EEPAAAPAPTKEEVLL 122
                  + YG FIQ +FDFLI+A AIFM +K+ NKL  K+   E+    P PTKEE +L
Sbjct: 64  -------IMYGNFIQTIFDFLIIAAAIFMFVKVFNKLTSKREEEEKKEELPEPTKEEEIL 116

Query: 123 TEIRDLLKEQNN 134
            EIRDLLK+QN+
Sbjct: 117 GEIRDLLKQQNS 128


>UniRef50_Q3ANR9 Large-conductance mechanosensitive channel n=24 Tax=Bacteria
           RepID=MSCL_CHLCH
          Length = 155

 Score =  130 bits (328), Expect = 9e-30,   Method: Compositional matrix adjust.
 Identities = 67/132 (50%), Positives = 94/132 (71%), Gaps = 14/132 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS++KEF+EFA++GNVVD+AVG+IIG AFG IV++LV+ +I+PPLGLLIGG+DF    + 
Sbjct: 1   MSVMKEFKEFAVKGNVVDMAVGIIIGGAFGAIVNNLVSQVILPPLGLLIGGVDFSSLYII 60

Query: 61  LRD-AQGDIP-----------AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
           L++ A    P           AV ++YGVF+ +VF F+I+AFA+F+ +K IN L R +  
Sbjct: 61  LKEGATQAAPYNSLAEATAAGAVTLNYGVFLNSVFSFVIMAFAVFLLVKSINMLRRTEGS 120

Query: 109 PAAAPAP--TKE 118
            +A PAP  TKE
Sbjct: 121 KSAVPAPSTTKE 132


>UniRef50_C7JGJ5 Large-conductance mechanosensitive channel n=9 Tax=Acetobacter
           RepID=C7JGJ5_ACEP3
          Length = 159

 Score =  127 bits (319), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 74/139 (53%), Positives = 92/139 (66%), Gaps = 10/139 (7%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR- 62
           + EFR F MRGNVVDLAVGVIIGAAF  IV+SLV DI  P +GLLIGGIDF    +TL+ 
Sbjct: 14  VGEFRAFIMRGNVVDLAVGVIIGAAFTSIVNSLVKDIFNPLIGLLIGGIDFSNLFITLKG 73

Query: 63  -------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN-RKKEEPAAAPA 114
                  +AQ    AV ++ G+F+  V  FLIVA AIF  +K + +L+ R+ E+P A P 
Sbjct: 74  PHLATLEEAQ-KAGAVTLNVGLFLNAVIQFLIVAMAIFWMVKALTRLHVREDEQPKAPPP 132

Query: 115 PTKEEVLLTEIRDLLKEQN 133
           P+K EVLL +IRD L   N
Sbjct: 133 PSKTEVLLEQIRDELAANN 151


>UniRef50_B8G6C2 Large-conductance mechanosensitive channel n=7 Tax=Bacteria
           RepID=MSCL_CHLAD
          Length = 137

 Score =  123 bits (309), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 70/139 (50%), Positives = 89/139 (64%), Gaps = 11/139 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQF---- 57
           ++ EFR F  RGNV+DLAVGVIIGAAF  I++SLV DII P LGLL+GG  D   +    
Sbjct: 1   MLNEFRTFINRGNVLDLAVGVIIGAAFTAIINSLVNDIINPLLGLLVGGRTDMSNYFLPL 60

Query: 58  ----AVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
               A TL +A+   P  V+ YG F+  V +FL+VAF IF+ ++  N+ N K  EP A P
Sbjct: 61  AGQTATTLAEARAAGP--VLAYGSFLNAVINFLLVAFVIFLIVRTANRFNPKPAEPPALP 118

Query: 114 APTKEEVLLTEIRDLLKEQ 132
            PT  E LL EIRDLL ++
Sbjct: 119 QPTPSERLLAEIRDLLAQR 137


>UniRef50_A6WVY7 Large-conductance mechanosensitive channel n=26 Tax=Bacteria
           RepID=MSCL_OCHA4
          Length = 137

 Score =  123 bits (308), Expect = 2e-27,   Method: Compositional matrix adjust.
 Identities = 65/136 (47%), Positives = 93/136 (68%), Gaps = 7/136 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GN+VDLA+GVIIG AFG +V+S+V DIIMP +GL+ GGIDF    + L 
Sbjct: 1   MLKEFKEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLA 60

Query: 63  D------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT 116
                  A        + YG F+  + +FLI+A+ +F+ +K +N++ +KKEE    P   
Sbjct: 61  GEPRATLAAAREAGATIAYGNFVTLLINFLIIAWVLFLVVKGMNRM-KKKEEAKPEPEAP 119

Query: 117 KEEVLLTEIRDLLKEQ 132
           +EEVLLTEIRDLL +Q
Sbjct: 120 REEVLLTEIRDLLAKQ 135


>UniRef50_A3MKN7 Large-conductance mechanosensitive channel n=286 Tax=Bacteria
           RepID=MSCL_BURM7
          Length = 143

 Score =  122 bits (306), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 78/150 (52%), Positives = 97/150 (64%), Gaps = 25/150 (16%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSIIKEF+EFA++GNV+DLA+GVIIG AF KIV S+V D+IMP +G+L GG+DF    V 
Sbjct: 1   MSIIKEFKEFAVKGNVMDLAIGVIIGGAFSKIVDSVVKDLIMPVIGVLTGGLDFSNKFVL 60

Query: 61  LRDAQGDIPA-----------------VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN 103
           L    G IPA                     YG FI  + +F+I+AF IF+ +K INKL 
Sbjct: 61  L----GQIPASFKGNPESFKDLQAAGVATFGYGSFITVLINFIILAFIIFLMVKFINKL- 115

Query: 104 RKKEEPAAAPAPTKEEV-LLTEIRDLLKEQ 132
           RK EE  AAPA T E+V LL EIRD LK++
Sbjct: 116 RKPEE--AAPAATPEDVLLLREIRDSLKQR 143


>UniRef50_Q1LIC3 Large-conductance mechanosensitive channel n=26 Tax=Bacteria
           RepID=MSCL_RALME
          Length = 144

 Score =  122 bits (305), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 72/141 (51%), Positives = 91/141 (64%), Gaps = 12/141 (8%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M ++ EF+ FAMRGNV+DLAVGVIIGAAFGKIV S+V D+IMP +G ++G +DF    V 
Sbjct: 1   MGMMSEFKTFAMRGNVIDLAVGVIIGAAFGKIVDSVVNDLIMPVIGRIVGKLDFSNMFVM 60

Query: 61  LRDAQGDIPAV----------VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA 110
           L D     P            V  YG F+  V +F+I+AF IFM ++  NK+  K+ EP 
Sbjct: 61  LADPPPGTPQTLDALKKAGVPVFAYGNFLTIVVNFVILAFIIFMMVRAFNKMREKEAEP- 119

Query: 111 AAPAPTKEE-VLLTEIRDLLK 130
           AAPA T E+ VLL EIRD LK
Sbjct: 120 AAPAVTPEDIVLLREIRDSLK 140


>UniRef50_Q3B3W2 Large-conductance mechanosensitive channel n=20 Tax=Bacteria
           RepID=MSCL_PELLD
          Length = 161

 Score =  117 bits (292), Expect = 1e-25,   Method: Compositional matrix adjust.
 Identities = 59/145 (40%), Positives = 95/145 (65%), Gaps = 15/145 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNVVD+AVG+I+G AFG IV++LV++++MPPLGLL GG+DF    V ++
Sbjct: 1   MLKEFKEFALKGNVVDMAVGIIVGGAFGSIVNTLVSEVMMPPLGLLTGGVDFSNLYVVMK 60

Query: 63  DAQGDIP-----------AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA 111
           +     P           AV ++YG+F+  +  F I+AF++F+ +K IN+L +K +   A
Sbjct: 61  EGVEPGPYAALANARAAGAVTLNYGLFLNALVSFTIMAFSVFILVKAINRLRQKAD---A 117

Query: 112 APAPTKEEVLLTEIRDLLKEQNNRS 136
           APAP  ++        L+ +Q +R 
Sbjct: 118 APAPPSKKT-CPYCLTLVPQQASRC 141


>UniRef50_Q2G9Z8 Large-conductance mechanosensitive channel n=3 Tax=Sphingomonadales
           RepID=MSCL_NOVAD
          Length = 155

 Score =  116 bits (291), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 66/146 (45%), Positives = 91/146 (62%), Gaps = 13/146 (8%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           + ++ EF++F  RGNV+DLAVGVIIG AFGKIV+SL   +IMP +G L GG+DF ++ V 
Sbjct: 10  LGMLGEFKKFIARGNVLDLAVGVIIGGAFGKIVTSLTESVIMPVVGWLTGGVDFTRYFVR 69

Query: 61  L----RDAQGDIPAV---------VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
           L     D +GD  +          ++ YG FI    +F+IVAF IF+ +K +N++  K E
Sbjct: 70  LGPVPADFKGDPTSYAELKAAGVPMIGYGDFITQAVNFVIVAFIIFLIVKAVNRMFEKPE 129

Query: 108 EPAAAPAPTKEEVLLTEIRDLLKEQN 133
           E  AAP+   E  LL EIRD LK + 
Sbjct: 130 EAPAAPSGPTEVELLAEIRDALKAKG 155


>UniRef50_C9LNV3 Large conductance mechanosensitive channel protein n=1
           Tax=Dialister invisus DSM 15470 RepID=C9LNV3_9FIRM
          Length = 168

 Score =  115 bits (289), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 62/126 (49%), Positives = 90/126 (71%), Gaps = 12/126 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDF------ 54
           M ++KEFR+FA+RGNVVD+AVGV+IG AFGKI+SSLV +IIMPP+G+++GG+DF      
Sbjct: 23  MGMMKEFRDFAVRGNVVDMAVGVVIGGAFGKIISSLVENIIMPPIGMIMGGVDFSNRFIN 82

Query: 55  --KQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAA 112
             K    TL +A+ ++   V+ YG F+  + DFLI+AF IF+ ++ +N+   K+E   AA
Sbjct: 83  LGKTPVATLAEAK-EMNVPVIAYGQFLNTIIDFLIIAFVIFLVVRQMNRAFPKEE---AA 138

Query: 113 PAPTKE 118
           PA T +
Sbjct: 139 PARTCQ 144


>UniRef50_A0M1G0 Large-conductance mechanosensitive channel n=10 Tax=Bacteroidetes
           RepID=A0M1G0_GRAFK
          Length = 148

 Score =  115 bits (289), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 57/140 (40%), Positives = 90/140 (64%), Gaps = 7/140 (5%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M I KEF+EFA++GN++D+AVG+IIG AF K+V  LV  IIMPPL +L  GI +      
Sbjct: 1   MGIFKEFKEFAVKGNMIDMAVGIIIGTAFNKVVDVLVKQIIMPPLSMLTDGISYANRKFV 60

Query: 61  LRD---AQGD---IPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPA 114
           LRD   A+GD   I  + + YG+ I+ + DF+++ F +F+ +K +N+   K ++P     
Sbjct: 61  LRDGIGAEGDVNYIEEISIGYGLLIETLIDFIVIGFVVFLVVKFMNRFRNKAQDPKNTEV 120

Query: 115 PTKEEV-LLTEIRDLLKEQN 133
            T +++ LL+ + D ++EQN
Sbjct: 121 VTPKDIELLSSLNDKMEEQN 140


>UniRef50_C0Z921 Large-conductance mechanosensitive channel n=36 Tax=Bacteria
           RepID=MSCL_BREBN
          Length = 154

 Score =  115 bits (288), Expect = 4e-25,   Method: Compositional matrix adjust.
 Identities = 61/124 (49%), Positives = 88/124 (70%), Gaps = 10/124 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV--- 59
           ++KEF+EFA++GNV+DLAVGV+IG AFGKIV+SLV DII P +GLL+G +DF    +   
Sbjct: 1   MLKEFKEFALKGNVMDLAVGVVIGGAFGKIVTSLVNDIITPLIGLLLGKVDFSGLFINLS 60

Query: 60  -----TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPA 114
                T+ +A+    A  ++YG+F+ +V DF+I+AF+IF+ IK +N+  R K+E   AP 
Sbjct: 61  GVPYKTIAEAK-TAHAATLNYGLFLNSVIDFVIIAFSIFIVIKQLNRFKR-KQEVEQAPV 118

Query: 115 PTKE 118
            TKE
Sbjct: 119 TTKE 122


>UniRef50_A2TYX0 Large-conductance mechanosensitive channel n=1 Tax=Polaribacter sp.
           MED152 RepID=A2TYX0_9FLAO
          Length = 138

 Score =  114 bits (285), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 61/139 (43%), Positives = 89/139 (64%), Gaps = 6/139 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV- 59
           M ++KEF++FAM+GN++D+AVG ++GAAF ++V+S    I+ P +GL+    DFK+    
Sbjct: 1   MGMLKEFKDFAMKGNLIDIAVGFVMGAAFKQVVTSFTGGIVSPLIGLIFEA-DFKKLKWV 59

Query: 60  ----TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
               TL DA   +  V + YG F+ NV DF+IVAF +FM +K IN   +K+E    AP  
Sbjct: 60  VKEGTLNDAGETVGQVAVLYGDFLTNVIDFIIVAFVMFMIVKGINATKKKEEPKPEAPKG 119

Query: 116 TKEEVLLTEIRDLLKEQNN 134
             +E LL +IRDLL +QN 
Sbjct: 120 PSQEELLEQIRDLLAKQNK 138


>UniRef50_A1B4B3 Large-conductance mechanosensitive channel n=45 Tax=Bacteria
           RepID=MSCL_PARDP
          Length = 145

 Score =  113 bits (282), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 69/149 (46%), Positives = 95/149 (63%), Gaps = 21/149 (14%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + KEF+EF  RGNV+DLAVG+IIGAAF  IV+SLVAD+I P +GLL GG DF    + L+
Sbjct: 1   MFKEFKEFIARGNVIDLAVGIIIGAAFTAIVNSLVADLINPIIGLLTGGTDFSGHYLVLK 60

Query: 63  DAQGDIP------------AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN-----RK 105
              G++P            A V  YG F+  V +FLI+A+A+F+ +K +N++      +K
Sbjct: 61  ---GEVPPGASLQVARDSGASVFAYGAFLSAVINFLIIAWAVFLLVKAVNRVQSAASRQK 117

Query: 106 KEEPAAAPAPTKEEVLLTEIRDLLKEQNN 134
           + E  AA  PT+EE LLTEIRD L+ +  
Sbjct: 118 EAEAEAAAGPTQEE-LLTEIRDELRARRT 145


>UniRef50_B1YKK2 Large-conductance mechanosensitive channel n=2 Tax=Bacillales
           RepID=MSCL_EXIS2
          Length = 129

 Score =  110 bits (275), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 67/134 (50%), Positives = 91/134 (67%), Gaps = 8/134 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + K F+EFA RGNV+DLAVGVI+GAAF  I+ SLV  I MP +G++IGGID K  +V + 
Sbjct: 1   MFKAFKEFAFRGNVIDLAVGVILGAAFSGIIKSLVDSIFMPLIGIIIGGIDVKGLSVEVG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
           +A        + YG F+Q   +F+++AFA+F+ +K IN   RK+E      APT EE LL
Sbjct: 61  NAN-------LLYGQFLQASIEFILIAFALFLFVKGINAFRRKEETTEEVAAPTTEEKLL 113

Query: 123 TEIRD-LLKEQNNR 135
           TEIRD L+++QN R
Sbjct: 114 TEIRDALVRQQNER 127


>UniRef50_A4CIE9 Large-conductance mechanosensitive channel n=7 Tax=Bacteroidetes
           RepID=A4CIE9_9FLAO
          Length = 136

 Score =  109 bits (273), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 58/137 (42%), Positives = 89/137 (64%), Gaps = 8/137 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F M GNV+DLAV V++ +A G +VS  V DI+MP +G   GG+DF    + L 
Sbjct: 1   MLKEFKKFIMTGNVIDLAVAVLLASAIGLVVSGFVNDIMMPIVGYFTGGVDFSDMKIVLS 60

Query: 63  D----AQGDI--PAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE-EPAAAPAP 115
           +    A G +  P   + YG +I ++ + +IV F +FM +K  NK+ +K+E +P A   P
Sbjct: 61  EAVVAADGTVEKPESAVRYGAWINSIINLIIVGFVLFMIVKSYNKVRKKEEPKPEAPKGP 120

Query: 116 TKEEVLLTEIRDLLKEQ 132
           T+E+ LL EIRDLLK++
Sbjct: 121 TQED-LLAEIRDLLKKK 136


>UniRef50_A7X204 Large-conductance mechanosensitive channel n=51 Tax=Staphylococcus
           aureus RepID=MSCL_STAA1
          Length = 120

 Score =  109 bits (272), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 62/131 (47%), Positives = 90/131 (68%), Gaps = 11/131 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNV+DLA+ V++GAAF KI+SSLV +IIMP +G + G +DF +      
Sbjct: 1   MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAK------ 54

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               +     + YG+FIQ+V DF+I+AFA+F+ +K+ N L  KKEE        +  VLL
Sbjct: 55  ----EWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTL-MKKEEAEEEAVVEENVVLL 109

Query: 123 TEIRDLLKEQN 133
           TEIRDLL+E+ 
Sbjct: 110 TEIRDLLREKK 120


>UniRef50_Q6MD32 Putative mechanosensitive channel of large conductance n=1
           Tax=Candidatus Protochlamydia amoebophila UWE25
           RepID=Q6MD32_PARUW
          Length = 133

 Score =  107 bits (268), Expect = 8e-23,   Method: Compositional matrix adjust.
 Identities = 55/125 (44%), Positives = 82/125 (65%), Gaps = 6/125 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M+ +KEF+EFA+RGN VDLA+G+IIG  F K V+SLV D+IMP +GLL+GG DF   ++ 
Sbjct: 1   MTWLKEFKEFALRGNRVDLAIGIIIGGVFSKAVNSLVTDVIMPLIGLLLGGADFSALSLK 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE-- 118
           L   +     V + YG+F+  + D LI++  IF+ IK +N+L  K+ + +     T+E  
Sbjct: 61  LHLPESAAAPVAVKYGIFVNTLVDLLILSSVIFIVIKGMNRLYEKRSKASC----TRECP 116

Query: 119 EVLLT 123
           E L+T
Sbjct: 117 ECLMT 121


>UniRef50_D2LWQ6 Large conductance mechanosensitive channel protein n=1 Tax=Bacillus
           cellulosilyticus DSM 2522 RepID=D2LWQ6_BACS4
          Length = 164

 Score =  107 bits (268), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 54/112 (48%), Positives = 78/112 (69%), Gaps = 9/112 (8%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV- 59
           MS  + FREFA+RGNVVD+ +GVIIGAAFG IV+S V+D++MPP+GLL+G ++F    + 
Sbjct: 1   MSFFRGFREFAIRGNVVDMGIGVIIGAAFGGIVTSFVSDVLMPPIGLLLGKVNFSNLYIN 60

Query: 60  -------TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
                  +L +AQ +  A  ++YG FI+ V  F+I+AFA ++ I  +NKL R
Sbjct: 61  LSGEHYSSLAEAQ-EAGAATVNYGAFIETVIHFVIIAFAAYLIIIQMNKLRR 111


>UniRef50_UPI000196C3D3 hypothetical protein CATMIT_02956 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196C3D3
          Length = 130

 Score =  107 bits (266), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 59/129 (45%), Positives = 86/129 (66%), Gaps = 8/129 (6%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           EF+EFA +GNV+D+AVGVI+G A   +V+SLV DIIMP L  +I      +    + +  
Sbjct: 7   EFKEFAFKGNVIDMAVGVILGTAITAVVTSLVQDIIMPVLSAII------KIPSDITELT 60

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK-LNRKKEEPAAAPAPTKEEV-LLT 123
             +  + + YG F+ N+ +FL++AF IF+ IK INK ++ +K+E  A PAP  E++ LL 
Sbjct: 61  LKVNNINIKYGSFLSNLINFLLMAFCIFICIKAINKVMSFRKKEEEAVPAPKPEDIALLE 120

Query: 124 EIRDLLKEQ 132
           EIRDLLKE+
Sbjct: 121 EIRDLLKEK 129


>UniRef50_D2R1B6 Large conductance mechanosensitive channel protein n=1
           Tax=Pirellula staleyi DSM 6068 RepID=D2R1B6_9PLAN
          Length = 166

 Score =  105 bits (263), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 68/166 (40%), Positives = 90/166 (54%), Gaps = 34/166 (20%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-GGIDFKQFAV 59
           M ++KEFR+FA+RGNV+DLAVGVIIG AFGKI SSLV D++MP LGL+    +DFK   +
Sbjct: 1   MGLLKEFRDFALRGNVIDLAVGVIIGGAFGKITSSLVGDVMMPALGLVANNALDFKSRYI 60

Query: 60  TLRDAQGDIPAV--------------------------VMHYGVFIQNVFDFLIVAFAIF 93
            L  A+    A                           V+ YG F+  V DF I+AF +F
Sbjct: 61  RLFSAEQLAAATKTTTEEANKLIDSGVPFSIVSENKLPVIAYGSFLTTVIDFAILAFCVF 120

Query: 94  MAIKLINK-------LNRKKEEPAAAPAPTKEEVLLTEIRDLLKEQ 132
           M +K++N        L + +   A    P  +E LL EIRDLLK +
Sbjct: 121 MVVKIMNTAIKRLEALRKAEVAAAPPAEPPAQEKLLMEIRDLLKAK 166


>UniRef50_UPI0001C42BC0 large-conductance mechanosensitive channel n=1 Tax=Bacillus
           pseudofirmus OF4 RepID=UPI0001C42BC0
          Length = 178

 Score =  105 bits (263), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 50/116 (43%), Positives = 76/116 (65%), Gaps = 7/116 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M+I+ EF+EFA+RGNV+D++VGVIIG  F KIV S V D+IMPP  +L G +DF    + 
Sbjct: 1   MNILHEFKEFAVRGNVIDMSVGVIIGTTFAKIVESFVEDVIMPPFSVLFGQVDFSNLYLN 60

Query: 61  LRD------AQGDIPAVVM-HYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP 109
           L D      A+ +   + M  YG+F+ ++  F IVAF +F+ ++ +N++ R  E+P
Sbjct: 61  LSDRRFNSFAEAEAAGIPMLKYGMFLNHIVHFAIVAFILFLFVRQMNRIRRPDEDP 116


>UniRef50_Q034S0 Large-conductance mechanosensitive channel n=4 Tax=Lactobacillus
           casei group RepID=MSCL_LACC3
          Length = 123

 Score =  105 bits (262), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 61/129 (47%), Positives = 84/129 (65%), Gaps = 10/129 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F MRGNV+DLAVGVIIG+AF  +V+SL  ++I P L +  G  D      T+ 
Sbjct: 1   MLKEFQKFIMRGNVLDLAVGVIIGSAFTGLVTSLTKNLINPILSMFAGKADLSGLYFTIL 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
            A+         YG FI +V +FLI+AF +F+ +K IN++   K  PA    PT+EE LL
Sbjct: 61  GAK-------FTYGNFINDVLNFLIIAFVVFLLVKGINRILPSK--PAKPAGPTQEE-LL 110

Query: 123 TEIRDLLKE 131
           TEIRDLLK+
Sbjct: 111 TEIRDLLKQ 119


>UniRef50_C7MN86 Large conductance mechanosensitive channel protein n=9 Tax=Bacteria
           RepID=C7MN86_CRYCD
          Length = 146

 Score =  104 bits (260), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 59/132 (44%), Positives = 81/132 (61%), Gaps = 12/132 (9%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +KEF+EF  RGNV+D+AVG+IIGAAF  IV+SLV+D++MP + L IGG DF   AVT   
Sbjct: 5   LKEFKEFVSRGNVMDMAVGIIIGAAFTAIVTSLVSDVVMPIVSLAIGGADFSSLAVTF-- 62

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI--------NKLNRKKEEPAAAPAP 115
             GD  A  ++YG FIQ + +F++VAF +F  +K I        +     +EE A    P
Sbjct: 63  GTGD-NAATLNYGKFIQAIVNFILVAFVVFCLVKAIATTEGHIASAKKDSQEESAVRECP 121

Query: 116 -TKEEVLLTEIR 126
             KEE+  +  R
Sbjct: 122 FCKEEIAASATR 133


>UniRef50_Q7UW50 Probable large-conductance mechanosensitive channel n=1
           Tax=Rhodopirellula baltica RepID=Q7UW50_RHOBA
          Length = 168

 Score =  104 bits (260), Expect = 8e-22,   Method: Compositional matrix adjust.
 Identities = 63/156 (40%), Positives = 97/156 (62%), Gaps = 26/156 (16%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI--GGIDFKQFA 58
           M +++EF+EFA++G+V+DLAVGV+IG AF  IV SLV +IIMPP+ LL    G++FK+ A
Sbjct: 15  MGLVQEFKEFALKGSVIDLAVGVVIGGAFSGIVKSLVDNIIMPPINLLTARSGVNFKEAA 74

Query: 59  VTLR-------------DAQG------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI 99
           +T+              + +G      D P  +++YG F Q +F+FL++A A+F+AIKLI
Sbjct: 75  LTIETESPKLDDAGKIIEGEGAEMLVQDYP--ILNYGPFTQTIFEFLLIALALFVAIKLI 132

Query: 100 NKLNRK---KEEPAAAPAPTKEEVLLTEIRDLLKEQ 132
           N    +   + E      P+++  LL EIRD L++ 
Sbjct: 133 NAARSRMEDEPEEEEVAKPSEDIQLLREIRDALQKS 168


>UniRef50_A6M387 Large-conductance mechanosensitive channel n=7 Tax=cellular
           organisms RepID=MSCL_CLOB8
          Length = 146

 Score =  103 bits (258), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 64/132 (48%), Positives = 84/132 (63%), Gaps = 8/132 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + KEF+EFAM+GN+V LA+GV+IG AF KIV+SLV DIIMP +GLL+G +DF     TL 
Sbjct: 1   MFKEFKEFAMKGNMVSLAIGVVIGGAFSKIVTSLVNDIIMPLVGLLMGRVDFSNLFFTLG 60

Query: 63  DAQ-------GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
                      D     ++YG+FI N+ DFLIVAF+IF+ I+ I+KL +KK E    P  
Sbjct: 61  SGNFKTVQEAKDAGVATVNYGIFINNIIDFLIVAFSIFIIIQQISKLTKKKGEN-IVPDK 119

Query: 116 TKEEVLLTEIRD 127
            K +   TEI  
Sbjct: 120 KKCKYCYTEINS 131


>UniRef50_A4CLF8 Large conductance mechanosensitive channel protein n=1
           Tax=Robiginitalea biformata HTCC2501 RepID=A4CLF8_9FLAO
          Length = 144

 Score =  103 bits (258), Expect = 1e-21,   Method: Compositional matrix adjust.
 Identities = 49/131 (37%), Positives = 80/131 (61%), Gaps = 1/131 (0%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           I+EF+ FA++GN+ D+A+G+IIG AF  +V++LV +I+ PPL      + F      +R+
Sbjct: 5   IREFKNFAIKGNMFDMAIGIIIGTAFNNVVNALVKEILTPPLAFFTSEVQFTNMRWVIRE 64

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV-LL 122
           A      + M YG+ ++ + DF I+A  IF+ IK +N++  + E+PA     T +E+ LL
Sbjct: 65  ATDTQEEITMGYGILLEALIDFGIIALTIFLLIKALNRIRSRAEDPADKAEVTPKEIELL 124

Query: 123 TEIRDLLKEQN 133
             I  L+ EQN
Sbjct: 125 ARIEGLMHEQN 135


>UniRef50_UPI0000DB7E8B PREDICTED: hypothetical protein, partial n=1 Tax=Apis mellifera
           RepID=UPI0000DB7E8B
          Length = 141

 Score =  101 bits (252), Expect = 7e-21,   Method: Compositional matrix adjust.
 Identities = 54/132 (40%), Positives = 81/132 (61%), Gaps = 17/132 (12%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M  I++F+ F +RGNV+DLAVG+++G AF  +V SLV ++IMPP+GLLIGG+DF    +T
Sbjct: 5   MKFIEQFKAFLLRGNVIDLAVGMVVGTAFTNMVKSLVDNVIMPPIGLLIGGVDFSNLFIT 64

Query: 61  LRD------------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
           LR             A     AV ++ G+FI  V   +I+ FAIF+ +K I+KL++    
Sbjct: 65  LRSGSKYPGPYETLGAAQAAGAVTLNIGLFINTVISLVIIGFAIFLVVKGIDKLHK---- 120

Query: 109 PAAAPAPTKEEV 120
            + AP  T ++ 
Sbjct: 121 -SPAPKATTKQC 131


>UniRef50_Q03D91 Large-conductance mechanosensitive channel n=16 Tax=Bacteria
           RepID=MSCL_PEDPA
          Length = 140

 Score =  100 bits (250), Expect = 1e-20,   Method: Compositional matrix adjust.
 Identities = 63/129 (48%), Positives = 80/129 (62%), Gaps = 9/129 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EF  RGNV+DLAVGVIIG AF  IV SLV  +I P +GL IGGIDF  + + + 
Sbjct: 1   MLKEFKEFVSRGNVLDLAVGVIIGGAFTSIVKSLVNYLINPLIGLFIGGIDFSDWVLKVA 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE--EV 120
            A          +G FI  V +FLI+AF +F+ +KL+NK   KKEE     A   E  E+
Sbjct: 61  GAT-------FKFGSFINAVINFLIIAFVVFILVKLVNKFLPKKEEQEDDEAEAIENSEI 113

Query: 121 LLTEIRDLL 129
            L EIRD L
Sbjct: 114 YLKEIRDAL 122


>UniRef50_Q1QDU6 Large-conductance mechanosensitive channel n=5 Tax=Bacteria
           RepID=MSCL_PSYCK
          Length = 149

 Score = 99.0 bits (245), Expect = 4e-20,   Method: Compositional matrix adjust.
 Identities = 56/117 (47%), Positives = 76/117 (64%), Gaps = 15/117 (12%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAV 59
           MS++ EF+EFA++GNV+DLAVGVIIG AF  I  SLV D+IMP +  ++GG I+FK   +
Sbjct: 1   MSMVSEFKEFALKGNVMDLAVGVIIGGAFATITKSLVEDVIMPIVAFIVGGEINFKNMFL 60

Query: 60  TLRDA------------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
            L DA               IP  V+ YG FI  + +FLI+AF IFM +K++N+L R
Sbjct: 61  ILGDAPEGVARTNDALKAAGIP--VLAYGSFITVLINFLILAFIIFMMVKMVNRLRR 115


>UniRef50_Q5NNP2 Large-conductance mechanosensitive channel n=5
           Tax=Sphingomonadaceae RepID=MSCL_ZYMMO
          Length = 154

 Score = 97.4 bits (241), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 63/158 (39%), Positives = 89/158 (56%), Gaps = 29/158 (18%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSI+ +F+ F  +GNV+ L + VI+G AF KI+SS+  D++MP +G + GG+DF  F + 
Sbjct: 1   MSILTDFKNFISKGNVLGLGIAVIMGDAFNKIISSVTGDLLMPIIGAVFGGVDFSGFFIR 60

Query: 61  LRDAQGDIPA-----------------VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN 103
           L    G +PA                  +  YG F+  V +F+IVAF +FM +KL  KL 
Sbjct: 61  L----GAVPAGYTGSLTSYNDLKKAGVPLFGYGQFLTVVVNFVIVAFILFMIMKLAAKLQ 116

Query: 104 R-------KKEEPAAAPAPTKEE-VLLTEIRDLLKEQN 133
           +       KKEE  A  APT E+ VLL EIRD L+ + 
Sbjct: 117 KELDKTEAKKEEKIAEAAPTPEDIVLLREIRDELRGKK 154


>UniRef50_B0T274 Large-conductance mechanosensitive channel n=42 Tax=Bacteria
           RepID=MSCL_CAUSK
          Length = 161

 Score = 97.1 bits (240), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 71/135 (52%), Positives = 84/135 (62%), Gaps = 6/135 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSI+KEFREF  RGNVVDLAVGVIIGAAF  IV SLV  +IMPP+GL+ GG+DF +    
Sbjct: 1   MSIVKEFREFIARGNVVDLAVGVIIGAAFNGIVKSLVDGVIMPPIGLVTGGLDFSKLQWV 60

Query: 61  LRDAQGDIPA---VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTK 117
           L+       A   V + YG FI  V  FLIVA  +F+ +KL+N + R      A  AP  
Sbjct: 61  LKPEDPVTEAVELVAIQYGAFINTVIQFLIVAVVVFLLVKLVNHIRRADAAEPAPEAPAA 120

Query: 118 EEV---LLTEIRDLL 129
                 LLTEIRDLL
Sbjct: 121 PTPEERLLTEIRDLL 135


>UniRef50_B2GJ27 Large-conductance mechanosensitive channel n=5 Tax=Actinomycetales
           RepID=B2GJ27_KOCRD
          Length = 144

 Score = 95.5 bits (236), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 59/134 (44%), Positives = 84/134 (62%), Gaps = 15/134 (11%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFA-VTL 61
           ++  F+EF M+GNV+DLAV VIIGAAF KIV++LV  ++MP +  ++G  +F  FA VTL
Sbjct: 1   MLSGFKEFIMKGNVMDLAVAVIIGAAFSKIVNALVESVLMPAISAVVGSPNFDTFAVVTL 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRKKE-EPAAAPAP 115
           R  +       + +GV +  V +FL++A A++  I     K+I + NR+   EP A PA 
Sbjct: 61  RGNE-------LKFGVLLTAVVNFLLIAAAVYFCIVLPMNKMIERRNRRMGIEPTAEPA- 112

Query: 116 TKEEVLLTEIRDLL 129
               VLLTEIRD L
Sbjct: 113 DPNTVLLTEIRDAL 126


>UniRef50_C0QYW6 Large-conductance mechanosensitive channel n=2 Tax=Brachyspira
           RepID=MSCL_BRAHW
          Length = 155

 Score = 94.4 bits (233), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 48/112 (42%), Positives = 76/112 (67%), Gaps = 12/112 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IKEF++F M+G+++D+AVG++IGAAF KIV+S V DI+MPP+G+++ GIDF    + ++
Sbjct: 1   MIKEFKKFIMKGSILDMAVGLVIGAAFTKIVNSFVDDILMPPIGMILSGIDFSNIFIVIK 60

Query: 63  ------------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL 102
                       +A  +  AVV+  GVFI  +  F+I A ++F+ IKL NK+
Sbjct: 61  KGTDTLGNYNSIEAARNAGAVVIGIGVFINAIISFIITALSLFIIIKLFNKI 112


>UniRef50_A9HW97 Large-conductance mechanosensitive channel n=98 Tax=Proteobacteria
           RepID=MSCL_BORPD
          Length = 148

 Score = 94.4 bits (233), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 64/141 (45%), Positives = 93/141 (65%), Gaps = 13/141 (9%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAVTLR 62
           +KEFR+FA++GN +DLAVGVIIGAAFGKIV S+V D+IMP +  ++GG +DF    + L 
Sbjct: 8   LKEFRDFAVKGNAIDLAVGVIIGAAFGKIVDSVVKDLIMPLVNYILGGSVDFSNKFLVLS 67

Query: 63  DAQG--------DIP---AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA 111
              G        D+    A+V+ +G F+  + +F+++A  +F+ +K IN   RK+EE  A
Sbjct: 68  APDGYAGPMTYADLTKAGAIVLAWGNFLTILINFILLALVVFIIVKAINAARRKEEEAPA 127

Query: 112 APAPTKEE-VLLTEIRDLLKE 131
            PA   E+ V+L EIRDLLK+
Sbjct: 128 EPAAPPEDVVVLREIRDLLKK 148


>UniRef50_C6XFL7 Large conductance mechanosensitive channel protein n=1
           Tax=Candidatus Liberibacter asiaticus str. psy62
           RepID=C6XFL7_LIBAP
          Length = 141

 Score = 94.0 bits (232), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 53/138 (38%), Positives = 82/138 (59%), Gaps = 11/138 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG-GIDFKQFAVTL 61
           +  EF++F  RGNV+DL+VG+IIG AF ++V S+V DI+MP +G ++G G DF  + + L
Sbjct: 7   VFNEFKKFIARGNVIDLSVGIIIGGAFNRVVQSIVEDIMMPLVGCVMGNGTDFSNYFLPL 66

Query: 62  RD-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPA 114
                    ++      V  YG F   + +F I+A  +F+ I+ +NKL ++ E     PA
Sbjct: 67  SSEIKSSLISEARKQGAVFAYGSFASVLVNFFILAGVVFVLIQFMNKLVKQTENVKNPPA 126

Query: 115 PTKEEVLLTEIRDLLKEQ 132
             +   LLTEIRDLL++ 
Sbjct: 127 EVQ---LLTEIRDLLQKN 141


>UniRef50_Q2JGX8 Large conductance mechanosensitive channel protein n=3 Tax=Frankia
           RepID=Q2JGX8_FRASC
          Length = 131

 Score = 92.8 bits (229), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 57/134 (42%), Positives = 74/134 (55%), Gaps = 12/134 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K FR+F MRGNVVDLAV V++G AF  +V+SLV  I  P +  + G  DF     T+  
Sbjct: 1   MKGFRQFLMRGNVVDLAVAVMVGTAFTAVVTSLVKTIFTPLIAAIFGKPDFSALTFTING 60

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEE----PAAAPAPTKE 118
           +       V  YG FI +V  FL VA  I+  + L +N +N ++      P   PA T E
Sbjct: 61  S-------VFRYGEFINSVIAFLSVATVIYFVVVLPLNTINERRTRGQVPPEEDPALTDE 113

Query: 119 EVLLTEIRDLLKEQ 132
             LLTEIRDLL E 
Sbjct: 114 ARLLTEIRDLLAEH 127


>UniRef50_C9RJE4 Large conductance mechanosensitive channel protein n=1
           Tax=Fibrobacter succinogenes subsp. succinogenes S85
           RepID=C9RJE4_FIBSS
          Length = 149

 Score = 92.4 bits (228), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 63/143 (44%), Positives = 88/143 (61%), Gaps = 14/143 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI---GGIDFKQFA 58
           S+I+EF+ FA +GN+VD+A+G+IIGAAFGKIV+S V DI+MP +  +I   GG +  +  
Sbjct: 9   SLIEEFKAFAFKGNIVDMAIGIIIGAAFGKIVNSFVNDIVMPLVTAVIAKCGGQNAGEGI 68

Query: 59  VTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK----LINKLNRKKEEPAAAPA 114
            TL     +   + + YG FI  V +FLIVAFA+F+ +K     +  + +KKE  AAA  
Sbjct: 69  KTLVYTTSE--GIAIPYGTFIGEVLNFLIVAFAVFLMMKKFLGFMQNMRKKKEAEAAAAP 126

Query: 115 PTKEEV-----LLTEIRDLLKEQ 132
                      LLTEIRDLLK +
Sbjct: 127 AAPPAPSAEEKLLTEIRDLLKNK 149


>UniRef50_D2MPY5 Large conductance mechanosensitive channel protein n=1
           Tax=Bulleidia extructa W1219 RepID=D2MPY5_9FIRM
          Length = 125

 Score = 92.4 bits (228), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 49/130 (37%), Positives = 82/130 (63%), Gaps = 8/130 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + + EF+EFA++GNV+DLAVGVIIG AF  I+ SL+ +II P +G+L    DF Q  + +
Sbjct: 3   NFMNEFKEFALKGNVMDLAVGVIIGGAFQAIIKSLIDNIINPIIGILFQA-DFSQVVIRM 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                   +V +  G F+  + +F+++AF +F+ +K IN+L +  +E  + P  ++E  L
Sbjct: 62  -------GSVNLGVGAFVSTIINFVLLAFVLFLMVKAINQLKKLNQEEESTPEKSEEAQL 114

Query: 122 LTEIRDLLKE 131
           L +I + LK+
Sbjct: 115 LEKILEQLKK 124


>UniRef50_C8NCV5 Large conductance mechanosensitive channel protein n=1
           Tax=Cardiobacterium hominis ATCC 15826
           RepID=C8NCV5_9GAMM
          Length = 143

 Score = 92.4 bits (228), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 58/132 (43%), Positives = 80/132 (60%), Gaps = 6/132 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F+ F  RGNVVDLAVGV++GAAFG +VS LV   I P +  L+G  +F     +L 
Sbjct: 1   MLSGFKTFIARGNVVDLAVGVVMGAAFGLVVSGLVESFINPLIAWLVGKPNFDSLMFSLP 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLN---RKKEEPAAAPAPTKE 118
              G+ P  V  YG  +  + +F +V+ AI++ I + +NKL    +KKEE  A PAP  E
Sbjct: 61  PLIGEEPT-VFQYGKILTAIVNFFLVSLAIYIFIIIPMNKLTASMKKKEEVEAPPAPPSE 119

Query: 119 EV-LLTEIRDLL 129
           E+ LL EIRD L
Sbjct: 120 EILLLREIRDSL 131


>UniRef50_B0K2H2 Large conductance mechanosensitive channel protein n=11
           Tax=Bacteria RepID=B0K2H2_THEPX
          Length = 126

 Score = 92.0 bits (227), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 59/137 (43%), Positives = 81/137 (59%), Gaps = 18/137 (13%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F+EF MRGNV+DLAV VIIG AF KIV+SLV D++ P +G + G  DF        
Sbjct: 1   MLKGFKEFIMRGNVLDLAVAVIIGGAFNKIVNSLVVDVLTPLIGAIFGAPDFSAIKF--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLNRKKEE------PAAAPAP 115
              G I       G FI  V +F+++A AI F  +  IN +  +KE+      P A+P P
Sbjct: 58  ---GPI-----SIGNFINAVINFIVIAAAIYFFVVAPINTIKNRKEKQKQQQTPQASPEP 109

Query: 116 TKEEVLLTEIRDLLKEQ 132
           ++E  LL EI D+LKE+
Sbjct: 110 SEEVKLLREILDMLKEK 126


>UniRef50_C1XQ99 Large conductance mechanosensitive channel protein n=1
           Tax=Meiothermus silvanus DSM 9946 RepID=C1XQ99_9DEIN
          Length = 132

 Score = 91.3 bits (225), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 59/134 (44%), Positives = 79/134 (58%), Gaps = 8/134 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +++ FR+F +RGNVVDLAV VIIG AFG +V S+V DII P +GL+ G  DF    +   
Sbjct: 1   MLQGFRDFILRGNVVDLAVAVIIGTAFGAVVDSMVKDIITPIIGLIGGQPDFANLRL-FA 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK----LNRKKEEPAAAPAPTKE 118
           DA+G      + YG F+  V  F I A  +++ I L  K    + +K + P    AP + 
Sbjct: 60  DAKGQ---GGIAYGSFLNAVISFFIKAAVVYLVIVLPMKRMVEMLKKPQAPEIPAAPPEN 116

Query: 119 EVLLTEIRDLLKEQ 132
            VLL EIRDLLK Q
Sbjct: 117 VVLLREIRDLLKAQ 130


>UniRef50_D1BNK2 Large conductance mechanosensitive channel protein n=3
           Tax=Veillonella RepID=D1BNK2_VEIPT
          Length = 155

 Score = 89.0 bits (219), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 49/137 (35%), Positives = 79/137 (57%), Gaps = 14/137 (10%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           + +F+ FA +GN++DLA+G+IIGAAF  +V+S+V ++ MP L +  GGIDF    + L  
Sbjct: 5   LNDFKAFAFKGNMMDLAIGMIIGAAFTALVNSVVNNLFMPVLSVFTGGIDFSNLYLPLST 64

Query: 64  AQGD------------IPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR--KKEEP 109
              D                V+ YG FI ++  FLI+AF +F+ ++ + K+ +  K+EE 
Sbjct: 65  GSKDAFMAGADIATARAAGSVLPYGTFITDLIQFLILAFVVFLMVRGLAKMMKSAKEEEV 124

Query: 110 AAAPAPTKEEVLLTEIR 126
           A APA  + +   +EI 
Sbjct: 125 AEAPATKECQFCKSEIN 141


>UniRef50_D1AZE9 Large conductance mechanosensitive channel protein n=1
           Tax=Sulfurospirillum deleyianum DSM 6946
           RepID=D1AZE9_SULD5
          Length = 142

 Score = 88.6 bits (218), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 52/125 (41%), Positives = 76/125 (60%), Gaps = 16/125 (12%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQF----- 57
           ++KEF+ F ++GNV+D+AVG I GAAF  +V SLV++IIMPP+GLL+G +DF        
Sbjct: 1   MLKEFKNFLIKGNVIDMAVGFIFGAAFATVVKSLVSNIIMPPVGLLLGNVDFSSLFIALD 60

Query: 58  ---AVTLRD-AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
               V+L D  +   PA+ +  GVF  +   F+I+ F +FM IK   K+  K+E     P
Sbjct: 61  GKEYVSLADLEKAGAPAIKL--GVFFNDFTSFIILGFVMFMMIKGYAKIAPKEE-----P 113

Query: 114 APTKE 118
            PT +
Sbjct: 114 LPTTK 118


>UniRef50_Q2N8W2 Mechanosensitive channel n=1 Tax=Erythrobacter litoralis HTCC2594
           RepID=Q2N8W2_ERYLH
          Length = 169

 Score = 87.4 bits (215), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 57/150 (38%), Positives = 86/150 (57%), Gaps = 23/150 (15%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS+  EF++F  RGNVVDLAVGV+IGAAF  IV+ L   I+MP +G + G IDF  + + 
Sbjct: 1   MSLGTEFKKFIARGNVVDLAVGVVIGAAFSGIVTQLTEAILMPLIGWIFGDIDFSNWFLR 60

Query: 61  LRDAQGDIP-----------------AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN 103
           L    G+IP                   ++ YG  I  + +FLIVAFA+FM ++ +NK++
Sbjct: 61  L----GEIPEGYEGALDNYEQLKEAGVAMIGYGALITALINFLIVAFALFMLVRSVNKVS 116

Query: 104 RK-KEEPAAAPAPTKEEVLLTEIR-DLLKE 131
            + K   A     +K + + T+ + D+LK+
Sbjct: 117 DEIKARQAETEDSSKSDDVPTDPQLDVLKK 146


>UniRef50_C5BF23 Putative uncharacterized protein n=1 Tax=Edwardsiella ictaluri
           93-146 RepID=C5BF23_EDWI9
          Length = 77

 Score = 87.4 bits (215), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 47/74 (63%), Positives = 55/74 (74%), Gaps = 5/74 (6%)

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK--EEPAAAPAPTKE 118
           +R A G  PA+V +YG FIQ +FDF+IV FAIFMAIK INKL R+K  E P   PAP+ E
Sbjct: 1   MRKAIGSTPALVANYGQFIQAIFDFIIVTFAIFMAIKPINKLRRQKTAETP---PAPSAE 57

Query: 119 EVLLTEIRDLLKEQ 132
            VLLTEIR+LLK Q
Sbjct: 58  AVLLTEIRELLKAQ 71


>UniRef50_B1V916 Putative large-conductance mechanosensitive channel n=1
           Tax=Candidatus Phytoplasma australiense
           RepID=B1V916_PHYAS
          Length = 134

 Score = 87.0 bits (214), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 53/129 (41%), Positives = 76/129 (58%), Gaps = 10/129 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M+  + F+ F  RGNV++LAV V+IG  F KIVSSLVADI+MPP  LL            
Sbjct: 1   MTFFQGFKNFITRGNVINLAVAVVIGQLFSKIVSSLVADIMMPPFSLLFNETK------G 54

Query: 61  LRDAQGDIPA-VVMHYGVFIQNVFDFLIVAFAIFMAIKLIN--KLNRKKEE-PAAAPAPT 116
           L+  +  I   V M+YG+F+QN+ +F+I +FAI++ + + +  KL + K E      +  
Sbjct: 55  LQGLKWCIKEDVYMNYGIFLQNILEFVIFSFAIYLILTIFSRTKLEKPKSELKLILESLQ 114

Query: 117 KEEVLLTEI 125
           KE  LL EI
Sbjct: 115 KEITLLQEI 123


>UniRef50_Q31LP8 Large-conductance mechanosensitive channel n=2 Tax=Synechococcus
           elongatus RepID=MSCL_SYNE7
          Length = 133

 Score = 86.3 bits (212), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 49/122 (40%), Positives = 74/122 (60%), Gaps = 10/122 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           I++F+ F ++GNVV+LAV VIIG AF KIVSS V D++MP +  LI G D++   +    
Sbjct: 12  IRDFQAFILKGNVVELAVAVIIGGAFNKIVSSFVGDLVMPLVNPLIPGGDWRTAVIG--- 68

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLT 123
                P   +  G F  +V DFLI+AF +++AI+ I +  RK+E   AA  P  ++ +L 
Sbjct: 69  -----PG--LKIGSFAGSVIDFLIIAFVLYLAIRAIERFKRKEEAVVAAAEPDVQQQMLA 121

Query: 124 EI 125
            +
Sbjct: 122 TL 123


>UniRef50_A9WMF7 Large-conductance mechanosensitive channel n=2 Tax=Micrococcineae
           RepID=MSCL_RENSM
          Length = 133

 Score = 86.3 bits (212), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 56/137 (40%), Positives = 82/137 (59%), Gaps = 10/137 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQ-FAVTL 61
           +IK FR+F ++GNVVDLAV V+IGAAFG +V++LV +IIMP +  ++G   F   +A  +
Sbjct: 1   MIKGFRDFILKGNVVDLAVAVVIGAAFGTVVTTLVNNIIMPLIAGIVGKPSFNDVWAFQI 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRKKEEPAAAPAPT 116
               G  PA  +  G FI  + +F+I+A AI+  +      +I + N K    A    P 
Sbjct: 61  ----GSDPANKLLLGAFITVLLNFVIIAAAIYFMVVVPMNHVIARRNAKLGIKAGEETPD 116

Query: 117 KEEVLLTEIRDLLKEQN 133
            + VLLTEIRD LK ++
Sbjct: 117 PQIVLLTEIRDALKSRS 133


>UniRef50_Q04FK1 Large-conductance mechanosensitive channel n=4 Tax=Leuconostocaceae
           RepID=MSCL_OENOB
          Length = 129

 Score = 85.1 bits (209), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 55/134 (41%), Positives = 80/134 (59%), Gaps = 8/134 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++ EF++F MRGN +DLAVGV++GAAF  IV S+V ++I P +G+  G +D      ++ 
Sbjct: 1   MLNEFKQFIMRGNAIDLAVGVVMGAAFTSIVKSIVTNLIGPIIGIFAGAVDLSSLKFSIG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
            A       V  YG  +  V +F+IV F IF+ IK INK  +K E+   A A + E  LL
Sbjct: 61  PA-------VFKYGAVLNQVINFIIVGFIIFLIIKAINKFFKKNEKKEDAEAES-EVKLL 112

Query: 123 TEIRDLLKEQNNRS 136
           T+IR  LK+ N  +
Sbjct: 113 TDIRAELKKSNQST 126


>UniRef50_B1XK85 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=B1XK85_SYNP2
          Length = 145

 Score = 85.1 bits (209), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 48/104 (46%), Positives = 68/104 (65%), Gaps = 7/104 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S   +F+ F MRGNV+DLAV V+IG AFG+IV+SLVADII P +      +     A  L
Sbjct: 6   SFWSDFQAFIMRGNVIDLAVAVVIGGAFGQIVNSLVADIITPAI------LQPALSAANL 59

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK 105
            DA G++    + YG+F+  V +FL++AFAIF+ I+ I K+ R+
Sbjct: 60  -DALGELSFNGIKYGLFLAAVINFLVIAFAIFLVIRAIEKMQRR 102


>UniRef50_C6WJF5 Large conductance mechanosensitive channel protein n=4
           Tax=Actinomycetales RepID=C6WJF5_ACTMD
          Length = 176

 Score = 84.7 bits (208), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 55/133 (41%), Positives = 80/133 (60%), Gaps = 8/133 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFK-QFAVTL 61
           +IK F++F MRGNV+DLAV V+IGAAFG IV++   ++I  PL  L+GG++    FAV L
Sbjct: 1   MIKGFKDFLMRGNVIDLAVAVVIGAAFGSIVTAFTNNLIN-PLVALVGGMENPVGFAVQL 59

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEE-PAAAPAPTKEE 119
               G  P   M +G  +  V +F+I+A  I+    L +NK+  ++E    A P+   + 
Sbjct: 60  ----GASPKTTMDFGALVTAVMNFVIIAAVIYFVFVLPMNKIKERRERGQEAGPSEPTDV 115

Query: 120 VLLTEIRDLLKEQ 132
            LL EIRDL+  Q
Sbjct: 116 ELLKEIRDLMVAQ 128


>UniRef50_Q2NK99 Large-conductance mechanosensitive channel n=2 Tax=Candidatus
           Phytoplasma asteris RepID=Q2NK99_AYWBP
          Length = 145

 Score = 84.7 bits (208), Expect = 9e-16,   Method: Compositional matrix adjust.
 Identities = 53/135 (39%), Positives = 77/135 (57%), Gaps = 13/135 (9%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           K F+ F  RGNV++LAV V+IG  F KIVSSLVADIIMP   LL        +   L+D 
Sbjct: 16  KGFKAFIARGNVINLAVAVVIGQLFAKIVSSLVADIIMPLFSLLFN------YTGALKDL 69

Query: 65  QGDIPA-VVMHYGVFIQNVFDFLIVAFAIFMAIKLI---NKLNRKKEEPAA---APAPTK 117
           +  I A   + YG F+Q + +FL+++F I+  + L+   N L ++K +        +  K
Sbjct: 70  KFTIKANTYLCYGNFLQTILEFLLLSFIIYTILTLMSWKNPLQKEKTDKNMLLLQQSLNK 129

Query: 118 EEVLLTEIRDLLKEQ 132
           E  LL EI+++LK  
Sbjct: 130 EIALLEEIKNILKSN 144


>UniRef50_C5RAB3 MscL family large conductance mechanosensitive ion channel n=1
           Tax=Weissella paramesenteroides ATCC 33313
           RepID=C5RAB3_WEIPA
          Length = 130

 Score = 84.3 bits (207), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 54/133 (40%), Positives = 76/133 (57%), Gaps = 9/133 (6%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           I EF++F MRGNV+DLAV  I+GAAF  +V S+V D+IMP +G++ G I F   ++    
Sbjct: 5   INEFKDFIMRGNVMDLAVAFIMGAAFQTVVKSVVDDLIMPLIGIITGSISFS--SIVWHV 62

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR--KKEEPAAAPAPTKEEVL 121
              DI       G FI  +  FL+ +FA+F+ +K I K     KK+      AP  E V+
Sbjct: 63  GSADIKV-----GSFIGTLITFLLTSFAVFLILKAIRKAQSMTKKQAEEEEIAPETELVV 117

Query: 122 LTEIRDLLKEQNN 134
           L EIRD L  + +
Sbjct: 118 LQEIRDALAAKKD 130


>UniRef50_C2BQ59 MscL family large conductance mechanosensitive ion channel n=2
           Tax=Corynebacterium RepID=C2BQ59_9CORY
          Length = 167

 Score = 81.3 bits (199), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 55/138 (39%), Positives = 78/138 (56%), Gaps = 11/138 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           ++++K F++F MRGNV++LA  VIIG+AF  IV S+   II P +  L G  +       
Sbjct: 3   ITMLKGFKDFIMRGNVIELATAVIIGSAFTAIVKSVTDSIIQPIINSL-GSAEVGAVGFH 61

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLN----RKKEEPAAAPAP 115
           + DA+       + +G  I    +FLI+A  ++  I + INKL     R+      APAP
Sbjct: 62  ITDAEN----TFVDFGAVISAAINFLIIAAVVYFLIVMPINKLTEAAKRRHGVDPEAPAP 117

Query: 116 TKEEVLLTEIRDLLKEQN 133
           T EE LL EIRDLL+ QN
Sbjct: 118 TSEE-LLAEIRDLLEAQN 134


>UniRef50_Q5HPJ2 Large-conductance mechanosensitive channel n=9 Tax=Bacteria
           RepID=MSCL_STAEQ
          Length = 116

 Score = 81.3 bits (199), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 60/129 (46%), Positives = 89/129 (68%), Gaps = 13/129 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNV+DLA+ V++GAAF KIV+SLV  IIMP +G L G ++F +      
Sbjct: 1   MLKEFKEFALKGNVLDLAIAVVMGAAFNKIVTSLVQYIIMPLIGKLFGSVNFAE------ 54

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               D     + YG+FIQ++ DF+I+AFA+F+ +K+ N + +K+E+       T   VLL
Sbjct: 55  ----DWSFWGIKYGLFIQSIIDFIIIAFALFIFVKIANTVMKKEEKEEEVEENT---VLL 107

Query: 123 TEIRDLLKE 131
           TEIRDLLK+
Sbjct: 108 TEIRDLLKK 116


>UniRef50_C0WF41 MscL family large conductance mechanosensitive ion channel n=2
           Tax=Corynebacterium RepID=C0WF41_9CORY
          Length = 165

 Score = 81.3 bits (199), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 54/137 (39%), Positives = 76/137 (55%), Gaps = 13/137 (9%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAVTL 61
           ++K F++F MRGNVV+LA  VIIG+AF  IV+S+   II P +       +D   F +T 
Sbjct: 1   MLKGFKDFIMRGNVVELATAVIIGSAFTAIVTSVTDSIIQPIINSFGSAEVDGLGFQIT- 59

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRKKEEPAAAPAPT 116
                D  + ++ +G  I    +FLI+A  ++  I     KL     R++     APAPT
Sbjct: 60  -----DNKSTLVDFGAVITAAINFLIIAAVVYFLIVMPLNKLTEASKRRQGVDPEAPAPT 114

Query: 117 KEEVLLTEIRDLLKEQN 133
            EE LL EIRDLL+ QN
Sbjct: 115 SEE-LLAEIRDLLQAQN 130


>UniRef50_B0S3E4 Large-conductive mechanosensitive channel n=2 Tax=Finegoldia magna
           RepID=B0S3E4_FINM2
          Length = 133

 Score = 81.3 bits (199), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 48/131 (36%), Positives = 74/131 (56%), Gaps = 15/131 (11%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F   GNV+DLAV VI+GAA  ++V  L+  +I P +G    G++ K+ AVTL 
Sbjct: 1   MLKEFKKFITEGNVMDLAVAVIMGAAVKEMVDGLINGLIAPLIGAATAGVNMKELAVTLA 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT------ 116
                   V + YG+F+  +  F+I+AF +F+ +K +NK  R       AP PT      
Sbjct: 61  -------GVKLQYGLFLDALVKFIIIAFVVFIMVKAVNK-GRDALHKEPAPEPTTKTCPY 112

Query: 117 -KEEVLLTEIR 126
            K E+ +T  R
Sbjct: 113 CKSEIDITATR 123


>UniRef50_A9KIC1 Large conductance mechanosensitive channel protein n=2
           Tax=Clostridiales RepID=A9KIC1_CLOPH
          Length = 147

 Score = 80.9 bits (198), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 48/119 (40%), Positives = 72/119 (60%), Gaps = 15/119 (12%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +KEFREFA++GNV++LAVGVIIG+AF  IV+SL  +I+ P +GL       +Q       
Sbjct: 5   LKEFREFALKGNVMNLAVGVIIGSAFQGIVTSLTDNILSPIIGLFT-----RQ---NFDS 56

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL-----NRKKEE--PAAAPAP 115
            Q +I  + + YG FI  + +F+I+AF +F+ +K +N++      RKK E  P     P
Sbjct: 57  LQLNIFGITLRYGAFITALINFVIMAFVVFLLVKGMNRILSFDDKRKKVEVKPTEKDCP 115


>UniRef50_A3CM47 Large conductance mechano-sensitive ion channel, putative n=44
           Tax=Streptococcus RepID=A3CM47_STRSV
          Length = 127

 Score = 80.9 bits (198), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 54/135 (40%), Positives = 80/135 (59%), Gaps = 14/135 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP-LGLLIGGIDFKQFAVTL 61
           ++K+ +EF +RGNV+DLAVGVII  AFG IV+SL+ D+I P  L  ++   + +Q +   
Sbjct: 1   MLKDLKEFLLRGNVIDLAVGVIIANAFGAIVTSLITDVITPLFLNPILKAANLEQISQLK 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK---LNRKKEEPAAAPA-PTK 117
            +         + YG F+  V +FL++   +F  +K   K   L +KKEE   APA PT+
Sbjct: 61  WNG--------IAYGNFLSAVINFLVIGTVLFFIVKSAEKAQSLAKKKEEVEEAPAGPTE 112

Query: 118 EEVLLTEIRDLLKEQ 132
            EV L EI+ LL E+
Sbjct: 113 LEV-LQEIKALLAEK 126


>UniRef50_C7H9Q8 Large conductance mechanosensitive channel protein n=1
           Tax=Faecalibacterium prausnitzii A2-165
           RepID=C7H9Q8_9FIRM
          Length = 152

 Score = 79.3 bits (194), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 43/96 (44%), Positives = 61/96 (63%), Gaps = 8/96 (8%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           +EF+ FAMRGNV+D+AVGV++G+AF  IV+SLV D+I P +GL     DF +  V + D 
Sbjct: 14  EEFKAFAMRGNVLDMAVGVVVGSAFTAIVNSLVGDVINPLIGLFFNN-DFSEVVVKIGDV 72

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN 100
                   +  G FI  + +FLIVAF +F+ +K  N
Sbjct: 73  D-------LKIGSFISAIINFLIVAFVLFLVLKAFN 101


>UniRef50_A5UVR8 Large-conductance mechanosensitive channel n=2 Tax=Roseiflexus
           RepID=MSCL_ROSS1
          Length = 126

 Score = 79.3 bits (194), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 62/130 (47%), Positives = 81/130 (62%), Gaps = 14/130 (10%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQG 66
           F+ F MRGNV+DLAVGV+IG AF  +V+SLV DI+M  +  LIG  DF    V       
Sbjct: 5   FKTFVMRGNVIDLAVGVVIGTAFSAVVNSLVNDILMAIVATLIGQPDFSDVLV------- 57

Query: 67  DIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLN---RKKEEPAAAPAPTKEEVLL 122
              AV    G FI  + +FLI++ A+ F+ +  INKL+   R+ E P A PAP+ EE LL
Sbjct: 58  -FGAV--RLGAFITTIVNFLIISAALYFLVVVPINKLSEFTRRNEPPPAPPAPSAEEKLL 114

Query: 123 TEIRDLLKEQ 132
           TEIRDLL++ 
Sbjct: 115 TEIRDLLRQN 124


>UniRef50_B2IVG3 Large conductance mechanosensitive channel protein n=2
           Tax=Cyanobacteria RepID=B2IVG3_NOSP7
          Length = 144

 Score = 79.3 bits (194), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 43/123 (34%), Positives = 75/123 (60%), Gaps = 13/123 (10%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG--GIDFKQFAVTL 61
           +++F+EFA +GNV+DLA+ VIIG AF ++++S V D+IMP +  LIG  G +++   +  
Sbjct: 12  LRDFQEFAFKGNVIDLAIAVIIGTAFSRVITSFVEDVIMPLINPLIGVTGKEWRTITIG- 70

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                  P + +  G F+  + DFLI+A  +F+AI+ +    R++E P  + +P+   V+
Sbjct: 71  -------PGIAI--GQFLGAIIDFLIIALILFVAIRTLQTFKRQEEVPVES-SPSDANVI 120

Query: 122 LTE 124
             E
Sbjct: 121 AQE 123


>UniRef50_Q8DHB2 Large-conductive mechanosensitive channel n=1
           Tax=Thermosynechococcus elongatus BP-1
           RepID=Q8DHB2_THEEB
          Length = 140

 Score = 79.0 bits (193), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 44/116 (37%), Positives = 71/116 (61%), Gaps = 15/116 (12%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           +EFREFA++GNV+DLA+ V++G AF +IV+S+V D+IMP +  LI G D+++  +TL   
Sbjct: 16  QEFREFALKGNVIDLAIAVVVGGAFSRIVTSVVEDLIMPLVNPLIPGGDWRE--LTLGSG 73

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
                   M  G F+ ++ DF ++A ++F+ +KLI         P   PAP + + 
Sbjct: 74  --------MRIGKFLGSLLDFGVIALSLFILLKLILPF-----LPNRPPAPEQRQC 116


>UniRef50_C8W9F9 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C8W9F9_ATOPD
          Length = 149

 Score = 78.6 bits (192), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 48/131 (36%), Positives = 74/131 (56%), Gaps = 12/131 (9%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-GGIDFKQFAVTLR 62
           ++EF+EF  +GNV+D+A+G+IIG AF  IV+SLV DII P + L+  GG +    ++ + 
Sbjct: 5   LEEFKEFIQQGNVMDMAIGIIIGGAFTAIVTSLVNDIINPFIKLISGGGTEVSGLSIPVP 64

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN------KLNRKKEEPAAAPAPT 116
             Q  I      +G FI  + +FLI+AF +F  +K +N      KL + KEE     A  
Sbjct: 65  GTQNGI-----DFGAFISAIINFLIIAFIVFCMVKALNKFMKASKLEKDKEEAVEEVAAP 119

Query: 117 KEEVLLTEIRD 127
                L E+++
Sbjct: 120 HCPHCLEEVKE 130


>UniRef50_A7VB12 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
           RepID=A7VB12_9CLOT
          Length = 141

 Score = 78.6 bits (192), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 51/114 (44%), Positives = 70/114 (61%), Gaps = 9/114 (7%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           +EF+EFA++GNV+D+A+GVIIG AF  +V+SL    I P +G  IGG + +     L D 
Sbjct: 6   QEFKEFALKGNVLDMAIGVIIGGAFSGLVTSLTDCFINPIIG-CIGGAEVQGKIHLLGDQ 64

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK-LNRKKEEPAAAPAPTK 117
             D       YG FI  V +F+I+AF IF+ +K I K L+  K+E AAAP   K
Sbjct: 65  YID-------YGSFITAVINFIIMAFIIFLLMKGIKKLLSLGKKEEAAAPLTRK 111


>UniRef50_Q82ZB4 Large-conductance mechanosensitive channel n=40 Tax=Lactobacillales
           RepID=MSCL_ENTFA
          Length = 149

 Score = 78.2 bits (191), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 55/138 (39%), Positives = 77/138 (55%), Gaps = 11/138 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IKEF+EF MRG+V+DLAVGV+IG+AF  IV+ +V  +I P + L+      K+ A    
Sbjct: 1   MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSA---D 57

Query: 63  DAQG----DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK---KEEPAAAPAP 115
           DA G     +  V  + G  I  +  FLI AF +F+ +K  NK+  +   +E       P
Sbjct: 58  DALGALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVP 117

Query: 116 TKEEVLLTEIRDLLKEQN 133
           T E+  L EIRDLL  Q 
Sbjct: 118 TSED-YLKEIRDLLAAQT 134


>UniRef50_A7B9R5 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7B9R5_9ACTO
          Length = 137

 Score = 77.8 bits (190), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 59/144 (40%), Positives = 81/144 (56%), Gaps = 17/144 (11%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQ-FAVTL 61
           +I+ F+EF  RGNVV+LAVGVIIGAAF  IV +LV  II P +  +IG  DF   F +TL
Sbjct: 1   MIQGFKEFISRGNVVELAVGVIIGAAFKNIVDALVDGIINPLIAAVIGKPDFSDAFILTL 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEEP----AAAPAPT 116
                      + +GV I  V +FL++A A+++ I + +N LN + ++      A     
Sbjct: 61  NGTD-------VKFGVLITAVINFLLMAIALYLCIIVPMNALNERMKKQAAADEAEAKAN 113

Query: 117 KEEV----LLTEIRDLLKEQNNRS 136
           KEE     LLTEIRD L +   R 
Sbjct: 114 KEESDEVKLLTEIRDALAQGTPRH 137


>UniRef50_B9CMP0 Large conductance mechanosensitive channel protein n=1
           Tax=Atopobium rimae ATCC 49626 RepID=B9CMP0_9ACTN
          Length = 142

 Score = 77.4 bits (189), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 44/117 (37%), Positives = 68/117 (58%), Gaps = 6/117 (5%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-GGIDFKQFAVTLRDA 64
           EF++F  RGNV+D+A+GVIIG AF  IV+SLV DI+ P + L+  GG +    ++ +   
Sbjct: 7   EFKDFIARGNVMDMAIGVIIGGAFMAIVNSLVNDIVNPFIKLISGGGTEVSGLSIPVAGT 66

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
           +  I      +G FI  + +FLI+A  +F+ +K INK  + K+E   +P       L
Sbjct: 67  EHGID-----FGSFISAIINFLIIAVIVFLLVKAINKFMKGKKESTDSPTQVCPHCL 118


>UniRef50_A6W442 Large conductance mechanosensitive channel protein n=2
           Tax=Actinomycetales RepID=A6W442_KINRD
          Length = 151

 Score = 77.0 bits (188), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 57/139 (41%), Positives = 82/139 (58%), Gaps = 7/139 (5%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFK-QFAV 59
           M +I+ F++F +RGNV+DLAV V+IGAAF  +V+SLV  +I P +  + G  +    + V
Sbjct: 1   MKLIEGFKDFVLRGNVIDLAVAVVIGAAFTGVVTSLVQGLIDPIIAAVGGSANLDGAWVV 60

Query: 60  TLRDAQGDIP---AVVMHYGVFIQNVFDFLIVAFAIFMAI-KLINKL--NRKKEEPAAAP 113
            LR      P    V +  G  +  V +F+IVA  ++  I   +N+L   RKK E AA  
Sbjct: 61  PLRTLHEGTPQEEVVGIQVGTVVSAVVNFVIVAAVVYFGILTPVNRLLALRKKGEVAAPA 120

Query: 114 APTKEEVLLTEIRDLLKEQ 132
           AP ++ +LLTEIRDLL  Q
Sbjct: 121 APAEDVLLLTEIRDLLARQ 139


>UniRef50_Q6AGE6 Large-conductance mechanosensitive channel n=7 Tax=Actinomycetales
           RepID=Q6AGE6_LEIXX
          Length = 145

 Score = 77.0 bits (188), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 52/144 (36%), Positives = 82/144 (56%), Gaps = 22/144 (15%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI--GGIDFKQFAVT 60
           ++ EF+EF +RGNV+DLAV V+IGAAF  IV+++V ++I P +G       +D +   V+
Sbjct: 1   MLSEFKEFILRGNVIDLAVAVVIGAAFTTIVTAIVTNLINPLIGAFFQANALD-ETMIVS 59

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKE--------EPAA 111
           L  +        + +G  +  +  FLI+A  ++ A    +NKL  ++E        EP  
Sbjct: 60  LNGSD-------IRFGAVLGAIVTFLIIAIVVYFAFVFPLNKLKERQERLRSKGVVEPG- 111

Query: 112 APAPTKEEVLLTEIRDLLKEQNNR 135
             AP  E  +LTEIRDLLK+Q ++
Sbjct: 112 --APVTELDVLTEIRDLLKKQQSQ 133


>UniRef50_Q98B35 Large-conductance mechanosensitive channel n=1 Tax=Mesorhizobium
          loti RepID=Q98B35_RHILO
          Length = 87

 Score = 77.0 bits (188), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 38/59 (64%), Positives = 48/59 (81%)

Query: 3  IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
          ++KEF+EF  +GNV+DLAVGVIIGAAFGKIV SLV DIIMP +G + GG+DF  + + L
Sbjct: 1  MLKEFQEFISKGNVMDLAVGVIIGAAFGKIVDSLVNDIIMPIVGAIFGGLDFNNYFLGL 59


>UniRef50_C5BZI9 Large conductance mechanosensitive channel protein n=1
           Tax=Beutenbergia cavernae DSM 12333 RepID=C5BZI9_BEUC1
          Length = 166

 Score = 77.0 bits (188), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 51/137 (37%), Positives = 81/137 (59%), Gaps = 8/137 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV-TL 61
           ++  F+EF  RGN V+LAVG++IGAAF  +++++V  ++ P +G + G  +     V TL
Sbjct: 1   MLSGFKEFIARGNAVELAVGIVIGAAFTAVITAVVEGVLNPLIGGIFGQPNLDNIWVWTL 60

Query: 62  R--DAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLNRKK---EEPAAAPAP 115
              D    IP   M  G+ +  + +F++VA AI F+ +  +N L R++   +EP  A  P
Sbjct: 61  NEGDPAAGIPPSEMKVGMVLTALVNFVLVAAAIYFLVVAPLNALARRRATGQEPEPA-IP 119

Query: 116 TKEEVLLTEIRDLLKEQ 132
            ++  LLTEIRDLL  Q
Sbjct: 120 AEDIQLLTEIRDLLARQ 136


>UniRef50_B4D701 Large conductance mechanosensitive channel protein n=2
           Tax=Verrucomicrobia RepID=B4D701_9BACT
          Length = 141

 Score = 76.6 bits (187), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 54/131 (41%), Positives = 72/131 (54%), Gaps = 14/131 (10%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            I  EF+ F M+GNV+DLAVG++IGAAFG +V      II P +G   GG D     V+L
Sbjct: 5   EIAGEFKTFIMKGNVIDLAVGLLIGAAFGAVVKDFTDGIINPLIGYFGGGKD-----VSL 59

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLNRKKEEP-AAAPAPTKEE 119
                     +   G+ I  +  FLI A  + F+ +K +NKL    E+  A AP P ++ 
Sbjct: 60  H-------LWIFDVGLVINAIIKFLITAVVLFFIFVKPMNKLKAMSEKKEAGAPPPPEDI 112

Query: 120 VLLTEIRDLLK 130
            LL EIRDLLK
Sbjct: 113 QLLREIRDLLK 123


>UniRef50_D1BCH3 Large conductance mechanosensitive channel protein n=1
           Tax=Sanguibacter keddieii DSM 10542 RepID=D1BCH3_SANKS
          Length = 164

 Score = 76.6 bits (187), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 53/139 (38%), Positives = 81/139 (58%), Gaps = 17/139 (12%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQ-FAVT 60
           +++  F+EF MRGN +DLAVGVIIGAAF  +V+++V ++  P +  + G  D     + T
Sbjct: 3   NVLNGFKEFIMRGNAIDLAVGVIIGAAFSAVVAAIVENLFTPLIAAIFGEPDLSSVLSFT 62

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLN--RKK---EEPAAAPA 114
           +  A   I       G  +  V +FL VA A++  + L +N L+  RKK   EEP     
Sbjct: 63  INGAAFSI-------GAVLNAVINFLFVAIALYFFVVLPLNHLSKLRKKGIIEEPE---G 112

Query: 115 PTKEEVLLTEIRDLLKEQN 133
           P+++ ++LT+IRDLL  QN
Sbjct: 113 PSEDVLILTQIRDLLLVQN 131


>UniRef50_A4AI90 Large-conductance mechanosensitive channel n=1 Tax=marine
           actinobacterium PHSC20C1 RepID=A4AI90_9ACTN
          Length = 137

 Score = 76.6 bits (187), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 53/142 (37%), Positives = 80/142 (56%), Gaps = 14/142 (9%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQ-FAVTL 61
           ++  F+ F +RGNV+DLAV V+IGAAF  +V+++V  +  P +G L           VT+
Sbjct: 1   MLSGFKTFILRGNVIDLAVAVVIGAAFTAVVNTIVEAVFNPLIGALFNAETLSTALPVTI 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI----KLINKLNRKKE----EPAAAP 113
             A G+    V+++G  I  +  FL+VA  ++ AI       NKL   ++    EP A  
Sbjct: 61  PTAGGE--DAVIYFGAVIAALVQFLLVAVVVYFAIVAPMNYANKLAAARKPVVIEPEA-- 116

Query: 114 APTKEEVLLTEIRDLLKEQNNR 135
            PT+ E+LL +IRDLL +QNN 
Sbjct: 117 GPTEAELLL-QIRDLLAKQNNS 137


>UniRef50_C7HUU0 Large conductance mechanosensitive channel protein n=2
           Tax=Anaerococcus RepID=C7HUU0_9FIRM
          Length = 135

 Score = 76.6 bits (187), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 43/110 (39%), Positives = 66/110 (60%), Gaps = 9/110 (8%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           KEF+EF  +GNVVDLA+G+I+G+AF  IV+++V  I+MP +  L  G+D++  AV    A
Sbjct: 3   KEFKEFISKGNVVDLAIGLIMGSAFTAIVTAVVDGILMPIISGLTAGVDYEDLAVNFFGA 62

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPA 114
           +       +  G  I  +  FLI++  +F+ +K +NK   KKEE   A  
Sbjct: 63  K-------LQIGSVINAIITFLIISLFLFLIVKALNK--AKKEEVVEATT 103


>UniRef50_A8LHK6 Large conductance mechanosensitive channel protein n=5
           Tax=Actinomycetales RepID=A8LHK6_FRASN
          Length = 169

 Score = 75.9 bits (185), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 50/130 (38%), Positives = 74/130 (56%), Gaps = 13/130 (10%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           ++ F++F MRGN+VDLA+ V++G AF  +V SLV +I  P +  + G  DF     T+ D
Sbjct: 26  LRGFKQFLMRGNIVDLAIAVVVGTAFTAVVQSLVKNIFTPLIAAIGGEPDFSSLTFTIND 85

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL----INKLNRK--KEEPAAAPAPTK 117
           ++         YG FI +V  F++VA  I+  I L     N++ R+  + EP   PA + 
Sbjct: 86  SK-------FRYGAFINDVIAFIVVAAVIYFVIVLPLAKANEMRRRGEEPEPQEEPAISD 138

Query: 118 EEVLLTEIRD 127
           E  LLTEIRD
Sbjct: 139 EAKLLTEIRD 148


>UniRef50_C8WNX6 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C8WNX6_EGGLE
          Length = 153

 Score = 75.1 bits (183), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 48/119 (40%), Positives = 69/119 (57%), Gaps = 9/119 (7%)

Query: 13  RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIP-AV 71
           +GNV+DLAV V+IG AF  IV+S+V+D+IMP + L+ GGIDF    + L    G  P A 
Sbjct: 14  QGNVMDLAVAVVIGTAFTAIVNSVVSDLIMPLISLVTGGIDFSDMKIPL----GTGPDAA 69

Query: 72  VMHYGVFIQNVFDFLIVAFAIFMAIKLINK---LNRKKEEPAAAPAPTKEEVLLTEIRD 127
              YG FI  V  FLI+A  +F+ +K +++   L R+ +      AP K    L E+ +
Sbjct: 70  AFTYGNFINAVIQFLIIALVVFLIVKALSRARMLTRRGKHIEEQDAP-KCPFCLEEVNE 127


>UniRef50_Q9RRR4 Large conductance mechanosensitive channel n=1 Tax=Deinococcus
           radiodurans RepID=Q9RRR4_DEIRA
          Length = 128

 Score = 74.3 bits (181), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 46/133 (34%), Positives = 72/133 (54%), Gaps = 10/133 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  FR+F +RGNVVDLAVGV+IGAAF  +V++     + P + L  GG    + A T  
Sbjct: 1   MLNGFRDFILRGNVVDLAVGVVIGAAFNNVVAAFTKAFLDPLIRLATGG--HGKVAGTF- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLNR--KKEEPAAAPAPTKEE 119
                +  +   +G F+  + +FL+ A  + F  +  +N      K+ E AA   P+ EE
Sbjct: 58  ----AVNGITFDWGTFVSTLINFLLTAAVLYFFVVMPMNAATERLKRSEKAAEAEPSNEE 113

Query: 120 VLLTEIRDLLKEQ 132
            LL EIRD ++ +
Sbjct: 114 KLLAEIRDAVRSR 126


>UniRef50_Q6AAH3 Large conductance mechanosensitive channel n=4 Tax=Bacteria
           RepID=Q6AAH3_PROAC
          Length = 122

 Score = 73.6 bits (179), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 53/134 (39%), Positives = 72/134 (53%), Gaps = 20/134 (14%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K F++F MRGN+++LAV  I+G AF  +V S    IIM  +G L G  +F         
Sbjct: 1   MKGFKDFLMRGNLIELAVAFILGGAFSTVVKSFTT-IIMDLIGKLGGTPNF--------- 50

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMA-IKLI----NKLNRKKEEPAAAPAPTKE 118
             G +P  V H G FI +V  F +++F I+   IK I     KL R K+EP AAP     
Sbjct: 51  -SGWVPGGV-HVGAFITDVISFFVMSFVIYFGLIKPIELATEKLKRTKDEPVAAPTTAD- 107

Query: 119 EVLLTEIRDLLKEQ 132
             LL EIRD L+ +
Sbjct: 108 --LLIEIRDELRSR 119


>UniRef50_A6GYI6 Large-conductance mechanosensitive channel n=4
           Tax=Flavobacteriaceae RepID=MSCL_FLAPJ
          Length = 138

 Score = 73.6 bits (179), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 56/138 (40%), Positives = 83/138 (60%), Gaps = 7/138 (5%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M    +F+   M+G+V+ LA  V+IG AFGKIV S V DIIMP +G+L GG+DF    + 
Sbjct: 1   MGFFADFKASLMKGDVLSLATAVVIGGAFGKIVGSAVDDIIMPIVGVLTGGVDFTTKFIA 60

Query: 61  LR-DAQGDI------PAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
           L   +  D+       A  + YG  +Q + +F+I++F IF+ ++   K  +K+E    AP
Sbjct: 61  LNGQSYADLAAAKTAGAACLTYGNLVQAIINFIIISFFIFVVLRAAEKAKKKEEAAPTAP 120

Query: 114 APTKEEVLLTEIRDLLKE 131
           A   +E LLT+IRDLLK+
Sbjct: 121 AGPSQEELLTQIRDLLKK 138


>UniRef50_UPI000050F91C putative large-conductance mechanosensitive channel protein n=1
           Tax=Brevibacterium linens BL2 RepID=UPI000050F91C
          Length = 158

 Score = 72.8 bits (177), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 50/133 (37%), Positives = 79/133 (59%), Gaps = 8/133 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K FR+F ++GNVV+LA  VIIG AF  IV++  +D I+ PL   +GG +    +  ++
Sbjct: 1   MLKGFRDFILQGNVVELATAVIIGGAFTAIVTAF-SDKIINPLIAAVGGAEGPALSFQIK 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLN--RKKEEPAAAPAPTKEE 119
           +   ++P   +  G  I    +FLIVA  + F+ I  +NKLN  RK+  P     PT E+
Sbjct: 60  E---NVPETTIDLGAVITAAINFLIVAAIVYFIIIVPMNKLNELRKRGAPEEEVPPTTED 116

Query: 120 VLLTEIRDLLKEQ 132
            LL +IR++L+ Q
Sbjct: 117 -LLGDIREILRTQ 128


>UniRef50_Q025U4 Large conductance mechanosensitive channel protein n=1
           Tax=Candidatus Solibacter usitatus Ellin6076
           RepID=Q025U4_SOLUE
          Length = 136

 Score = 72.0 bits (175), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 40/102 (39%), Positives = 61/102 (59%), Gaps = 3/102 (2%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK F+EF ++ NV+ LAV VI+G A GK+VSSL AD+IMP + L++   D++     L 
Sbjct: 1   MIKGFKEFLLKNNVLALAVAVIVGGAVGKVVSSLAADVIMPVISLVLPAGDWRTAKFVLG 60

Query: 63  DA---QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
                 G      ++YG F  +V DFLI+A  +++  K + K
Sbjct: 61  KTVGPDGKETLNTLNYGSFFGSVVDFLIIALVVYLMTKALIK 102


>UniRef50_C4FVI2 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FVI2_9FIRM
          Length = 128

 Score = 71.2 bits (173), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 47/131 (35%), Positives = 71/131 (54%), Gaps = 8/131 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           I +EFR F  + N++ LAV VI+G AF  IV+SLV DI MP L  + G       A+ + 
Sbjct: 4   IFEEFRGFIAKDNIITLAVAVILGGAFSSIVTSLVNDIFMPILVAVTGQATVSGIALRIG 63

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE-EPAAAPAPTKEEVL 121
           +         +  G F+Q V +F+I+ F +F+ +K + K   K    P A PA   E+ L
Sbjct: 64  NTY-------LGVGNFLQAVINFVIIGFLLFLTLKALGKAQGKDLINPPAPPAGPSEKDL 116

Query: 122 LTEIRDLLKEQ 132
           L +I + LK++
Sbjct: 117 LQDILNELKKE 127


>UniRef50_A0JZ24 Large conductance mechanosensitive channel protein n=1
           Tax=Arthrobacter sp. FB24 RepID=A0JZ24_ARTS2
          Length = 130

 Score = 70.9 bits (172), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 50/144 (34%), Positives = 75/144 (52%), Gaps = 31/144 (21%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQG 66
           F+ F M+GNVVDLAV V++GAAF  +V+S+V  ++ P +G L              +A+G
Sbjct: 4   FKNFIMKGNVVDLAVAVVMGAAFSAVVTSIVEGLLTPLIGRLF-------------NAKG 50

Query: 67  --DIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRK-------KEEPAAA 112
             D+      YG  I +V  FL+V  +I+  +      +I + NR+       KEE A  
Sbjct: 51  IEDMQWEGFMYGSVISSVISFLLVGASIYFVVVLPMNHMIERRNRRLGIGTEVKEEAAED 110

Query: 113 PAPTKEEVLLTEIRDLLKEQNNRS 136
           P    +  LLTEIRD L+  + R+
Sbjct: 111 P----QIALLTEIRDSLRSGSTRA 130


>UniRef50_C6R3M2 Large conductance mechanosensitive channel protein n=1 Tax=Rothia
           mucilaginosa ATCC 25296 RepID=C6R3M2_9MICC
          Length = 147

 Score = 70.5 bits (171), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 44/134 (32%), Positives = 77/134 (57%), Gaps = 14/134 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F +RGNV+DLAVG+I+G AF  +V++LV  ++MP + +L+   +F +F V  +
Sbjct: 24  MLKGFKDFLIRGNVIDLAVGLIMGTAFTAVVNALVQSVLMPAISMLVKSPNFDEFLVFDQ 83

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL----INKLNRKKEEPAAAPAPTKE 118
                     +  GVF+  V +F+++A A++ A+ L    + +L  K +          E
Sbjct: 84  ----------IKVGVFLTAVVNFILIAAAVYFAVVLPVQKLTELAAKNKAEEEEEEEETE 133

Query: 119 EVLLTEIRDLLKEQ 132
             LL EIRD L ++
Sbjct: 134 IALLKEIRDALAKK 147


>UniRef50_C4FGI6 Putative uncharacterized protein n=1 Tax=Bifidobacterium angulatum
           DSM 20098 RepID=C4FGI6_9BIFI
          Length = 179

 Score = 69.7 bits (169), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 46/132 (34%), Positives = 76/132 (57%), Gaps = 11/132 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           IK F++F  RG+++D+AVGV++G+A   +V+S+V  +I P +G +IGG+      +T+  
Sbjct: 44  IKGFKKFISRGSMIDMAVGVVMGSAVTTVVNSIVNHLISPLIG-MIGGVPDMSGVLTIT- 101

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKL-NRKKEEPAAAPAPTKEE-- 119
                    + +G  +  + +FL++  A+++ I L INKL +    E A    PT EE  
Sbjct: 102 ----FNGATISFGAILNAIINFLLIGVAVYLCIVLPINKLRDMGANEEAENTEPTTEEQT 157

Query: 120 -VLLTEIRDLLK 130
             +L EIRD LK
Sbjct: 158 LAVLQEIRDELK 169


>UniRef50_D0WJR5 Large conductance mechanosensitive channel protein n=1
           Tax=Actinomyces sp. oral taxon 848 str. F0332
           RepID=D0WJR5_9ACTO
          Length = 172

 Score = 69.7 bits (169), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 48/133 (36%), Positives = 76/133 (57%), Gaps = 11/133 (8%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           ++I+ F++F MRGNV++LAV V+I  AF  IV++LV  +I P +G L G  +F       
Sbjct: 23  TMIEGFKKFIMRGNVIELAVAVVIADAFSPIVNNLVGKVINPTIGGLFGKPNFNNI---- 78

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNR---KKEEPAAAPAPTK 117
              +  +    +  G  +  +  FL++A A+++A+   +NKLN    K++   A  A   
Sbjct: 79  --GEFHVGDATVQPGTVLTALIAFLLIAAAVYLALVFPMNKLNERMAKRKGLNAEEAEVS 136

Query: 118 EEV-LLTEIRDLL 129
           +EV LLTEIRD L
Sbjct: 137 DEVRLLTEIRDAL 149


>UniRef50_B3QZY1 Large-conductance mechanosensitive channel n=1 Tax=Candidatus
           Phytoplasma mali AT RepID=B3QZY1_PHYMT
          Length = 139

 Score = 69.7 bits (169), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 40/115 (34%), Positives = 69/115 (60%), Gaps = 3/115 (2%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           K F++F  +GNV++L++  +I   F KIV+SL +DIIMP + LL    D   F+  LR  
Sbjct: 13  KGFKKFINKGNVLNLSIAFVISQLFSKIVNSLSSDIIMPFMNLLFSS-DKNDFS-DLRFR 70

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEE 119
                 + ++YG F++ VF+FLI++F I++ + ++ + N   E+     + TKE+
Sbjct: 71  ITSNSNIYIYYGKFLKTVFEFLIMSFFIYIILIIVFRQNLNSEK-VNIESLTKEQ 124


>UniRef50_C1RGF4 Large conductance mechanosensitive channel protein n=1
           Tax=Cellulomonas flavigena DSM 20109 RepID=C1RGF4_9CELL
          Length = 201

 Score = 68.6 bits (166), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 48/139 (34%), Positives = 75/139 (53%), Gaps = 12/139 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQF---AV 59
           + + F++F  RGN ++LAVGV++GAAF  +VS+L    I P +G + G  +         
Sbjct: 31  VFQGFKDFISRGNAIELAVGVVVGAAFTSVVSALQDAFINPLIGWIFGKPNLDNLWNIGP 90

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKK-----EEPAAAP 113
              + +    A  +  GV +  +  FLI A AI+  I L +N L  ++     EEPA   
Sbjct: 91  YTWNEEIAAEATPIQVGVILSALLQFLITAAAIYFLIVLPLNALAARRKQGVEEEPA--- 147

Query: 114 APTKEEVLLTEIRDLLKEQ 132
           AP ++ +LL EIRDLL ++
Sbjct: 148 APAEDILLLQEIRDLLSQR 166


>UniRef50_C4LHF9 Transport protein of the large conductance mechanosensitive ion
           channel family n=4 Tax=Corynebacterineae
           RepID=C4LHF9_CORK4
          Length = 187

 Score = 68.2 bits (165), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 51/138 (36%), Positives = 76/138 (55%), Gaps = 8/138 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K FR+F MRGNV++LA+ V+IG+AF  IV++    II P +    GG +   +    R
Sbjct: 1   MLKGFRDFIMRGNVIELAMAVVIGSAFTAIVTAFTKYIINPLIACF-GGANTDGWG--FR 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLN--RKKEEPAA-APAPTKE 118
             +G+     + +G  +  V +FLI+A  + F+ +  +NKL   RKK         P  E
Sbjct: 58  LIRGN-EKTFLDFGSVLTAVINFLIIAAVVYFILVAPMNKLEEIRKKHMGVKEEEVPVTE 116

Query: 119 EVLLTEIRDLLKEQNNRS 136
           + LL EIRDLL  QN  S
Sbjct: 117 KDLLLEIRDLLAAQNQVS 134


>UniRef50_D2B464 Large conductance mechanosensitive channel protein n=6
           Tax=Actinomycetales RepID=D2B464_STRRD
          Length = 134

 Score = 68.2 bits (165), Expect = 8e-11,   Method: Compositional matrix adjust.
 Identities = 46/129 (35%), Positives = 69/129 (53%), Gaps = 14/129 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F++F MRGNVV+LA+ V+IGAAF  IV+S V D++ P +  + G  DF    +TLR
Sbjct: 1   MLSGFKKFLMRGNVVELAIAVVIGAAFTAIVNSFVKDVLTPLIAAIGGQPDFS--GLTLR 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
              G+I      YG+F+  +  FL+VA  I+        L  +  E  +A    +EE   
Sbjct: 59  IGAGEI-----RYGLFLNALIAFLMVAAVIYF-------LVVRPYERISARFAAREEATH 106

Query: 123 TEIRDLLKE 131
            E  + L E
Sbjct: 107 RECPECLSE 115


>UniRef50_Q8EW76 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           penetrans RepID=Q8EW76_MYCPE
          Length = 215

 Score = 67.4 bits (163), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 39/102 (38%), Positives = 60/102 (58%), Gaps = 9/102 (8%)

Query: 5   KEFREF-AMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGL--------LIGGIDFK 55
           KEF++  + RGN++DLAV +IIG AF  IV+SLV DIIMP +G         L+  +D  
Sbjct: 20  KEFKKLVSSRGNLIDLAVALIIGTAFTAIVTSLVNDIIMPLIGAAAGKSLSELVWYLDIN 79

Query: 56  QFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK 97
                L +   +  A+++ YG F+Q + +F I+A  +F  +K
Sbjct: 80  NQPHFLPNGDINPQAIIIKYGNFLQVIINFFIIALTMFSVVK 121


>UniRef50_D0P2C5 Large Conductance Mechanosensitive Ion Channel (MscL) Family n=2
           Tax=Phytophthora infestans T30-4 RepID=D0P2C5_PHYIN
          Length = 191

 Score = 67.0 bits (162), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 38/112 (33%), Positives = 70/112 (62%), Gaps = 17/112 (15%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG-GIDFKQFAV- 59
           +++ +F+EF  +GN++++AVG+I+G++F  I++SLV DI+ P + L    GI    + V 
Sbjct: 35  ALLTDFQEFIQQGNMLNMAVGLILGSSFSAILNSLVVDILSPIISLFTERGIANHYWPVR 94

Query: 60  --------------TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK 97
                         T ++A+ D  AV ++YG+FI+N+ +F+I A  +F+A+K
Sbjct: 95  CPSTTTVCSGETWQTWKEAR-DAGAVTINYGLFIENIMNFVINALFLFIAVK 145


>UniRef50_Q6KH26 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           mobile RepID=Q6KH26_MYCMO
          Length = 151

 Score = 66.6 bits (161), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 45/128 (35%), Positives = 70/128 (54%), Gaps = 20/128 (15%)

Query: 13  RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG--GIDFKQFAVTLRDAQGDIPA 70
           RGN++ LAVG+++G  FG +V+S   DI++  +G+ I   GI+   F+        D+  
Sbjct: 26  RGNILMLAVGLLLGTVFGALVASFANDILLGAIGIGINALGININNFS--------DLSF 77

Query: 71  VVMHYGVFIQNVFDFLIVAFAIFMA------IKLINKLNRKKEEP----AAAPAPTKEEV 120
             + YG FI  +  F+IV+  IF A      I+ I   N KK+ P     AAP P+ +E+
Sbjct: 78  QTIRYGNFISALLTFIIVSLFIFFALFIYFVIRNIRLDNLKKKYPERYVVAAPKPSTDEL 137

Query: 121 LLTEIRDL 128
           +L E+R L
Sbjct: 138 ILEELRTL 145


>UniRef50_B5Y8I7 Large conductance mechanosensitive channel protein n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y8I7_COPPD
          Length = 127

 Score = 66.2 bits (160), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 49/138 (35%), Positives = 70/138 (50%), Gaps = 19/138 (13%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F+ F  RGNV+DLA+ VIIGAAF  +V SLV DI  P LG+L G  DF  + V   
Sbjct: 1   MLKGFKAFLSRGNVLDLAIAVIIGAAFNSVVKSLVEDIFTPLLGMLGGLPDFSSWKVG-- 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-------AIKLINKLNRKKEE-PAAAPA 114
                     +  G F+ ++  FL  A  I+        A+K   K  ++ E    A   
Sbjct: 59  ---------PLMLGSFVNSLLSFLFTAAVIYFVLVAPAEALKNAAKEKQRAETLDKATET 109

Query: 115 PTKEEVLLTEIRDLLKEQ 132
           P +E  LL  I +LL+++
Sbjct: 110 PPEEIQLLRRIVELLEKK 127


>UniRef50_A7HBZ5 Large conductance mechanosensitive channel protein n=1
           Tax=Anaeromyxobacter sp. Fw109-5 RepID=A7HBZ5_ANADF
          Length = 139

 Score = 66.2 bits (160), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 41/113 (36%), Positives = 62/113 (54%), Gaps = 7/113 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            + KEFREF ++ NV+ LA GV+IGAA GK+VS +V  ++MP +GLL+ G D        
Sbjct: 13  GLAKEFREFLLKQNVIALAAGVVIGAAIGKVVSGIVDFVVMPVVGLLLPGQD------EW 66

Query: 62  RDAQGDIPAV-VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
           R A+ DI     + YG  +  + +F I+A  +F+ +K   +         A P
Sbjct: 67  RQAKLDIGGGNAIGYGEVVGRLVEFGIIALVVFLVLKAFVRAPPPPAPTKACP 119


>UniRef50_B4V9Z0 Mechanosensitive channel n=3 Tax=Streptomyces RepID=B4V9Z0_9ACTO
          Length = 172

 Score = 65.5 bits (158), Expect = 5e-10,   Method: Compositional matrix adjust.
 Identities = 49/143 (34%), Positives = 72/143 (50%), Gaps = 13/143 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S++  F+ F MRGNV+DLAV V+IGAAF  IV+S+V  II P +G  +G      ++  L
Sbjct: 7   SVLAGFKAFLMRGNVIDLAVAVVIGAAFTNIVNSVVKGIIGPLVG-AVGTKSLDGYSSCL 65

Query: 62  R-----DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF------MAIKLINKLNRKK-EEP 109
           +      A+G+   V + +G  +     F+I A  ++      MA  L  +  R+K  E 
Sbjct: 66  KGPCGVTAKGEPTGVNILWGSVLNATLTFVITAAVVYFLMVLPMAKYLARQEQRRKAREG 125

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQ 132
                   E  +L EIRD L  Q
Sbjct: 126 VQETMEITELEVLKEIRDTLVAQ 148


>UniRef50_P73553 Large-conductance mechanosensitive channel n=2 Tax=Chroococcales
           RepID=MSCL_SYNY3
          Length = 145

 Score = 65.1 bits (157), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 43/114 (37%), Positives = 63/114 (55%), Gaps = 14/114 (12%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           ++F++F +RGNVVDLAV V+IG AF  IV++ VA ++   L  ++      Q        
Sbjct: 14  RDFKDFILRGNVVDLAVAVVIGGAFTSIVNAFVAWLMAVLLQPVLDQAGVSQLQ------ 67

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK---EEPAAAPAP 115
             D+P   +  G  +  + +FLI+AF IF+ IK I K+ RKK   EE  A   P
Sbjct: 68  --DLP---LGLGELVIAIINFLIIAFVIFLIIKAIEKMQRKKAVEEEIVAEAQP 116


>UniRef50_B3DRI7 Large-conductance mechanosensitive channel n=17
           Tax=Actinobacteridae RepID=B3DRI7_BIFLD
          Length = 168

 Score = 64.7 bits (156), Expect = 8e-10,   Method: Compositional matrix adjust.
 Identities = 43/139 (30%), Positives = 77/139 (55%), Gaps = 16/139 (11%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQ-FAVTLRDAQ 65
           F++F  RG+++D+AVGV++G+A   +V+S+V ++I P +G++ G  D      +T  ++ 
Sbjct: 36  FKKFLSRGSMIDMAVGVVMGSAVTAVVNSIVDNLISPLIGMIGGVPDLSGLLTITFNNS- 94

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNR----KKEEPAAAPAPTKEE- 119
                  + +G  +  + +FL+V  A++  + L INKL      + E  A    P+ EE 
Sbjct: 95  ------TVSFGAILNALINFLLVGVAVYFCVILPINKLRDLTAIQDEADAEEQGPSVEEQ 148

Query: 120 --VLLTEIRDLLKEQNNRS 136
               L EIRD LK+ N+ +
Sbjct: 149 TLATLQEIRDELKKANDSA 167


>UniRef50_C7MC43 Large conductance mechanosensitive channel protein n=1
           Tax=Brachybacterium faecium DSM 4810 RepID=C7MC43_BRAFD
          Length = 151

 Score = 64.7 bits (156), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 10/137 (7%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K F++F M+GNV+DLAVGV+IG+AF  ++++ V ++I P + +  GG +    +  +  
Sbjct: 1   MKGFKDFVMQGNVIDLAVGVVIGSAFTALITAFVENLIQPVINVF-GGSNVDGLSFKIIQ 59

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVA----FAIFMAIKLINKLNRKKEE-PAAAPAPTKE 118
           A     A  +  G  +  +  FLI A    F   + I    +L+RK+   P        E
Sbjct: 60  AN---EATRIDVGGVLSAIIAFLITAAVVYFVFVLPISAARRLDRKRRGLPEEEETSVSE 116

Query: 119 E-VLLTEIRDLLKEQNN 134
           + VLLTEIRD L  Q  
Sbjct: 117 DIVLLTEIRDALTVQQG 133


>UniRef50_Q5SKL6 Large-conductance mechanosensitive channel n=2 Tax=Thermus
          thermophilus RepID=Q5SKL6_THET8
          Length = 124

 Score = 63.9 bits (154), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 39/92 (42%), Positives = 54/92 (58%), Gaps = 11/92 (11%)

Query: 5  KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
          ++ ++F MRGNVVDLAV VIIG AF ++VSSLVAD+I P +G L G  DF    +     
Sbjct: 3  RDLKDFLMRGNVVDLAVAVIIGTAFSQVVSSLVADVITPLIGALGGVPDFSGIRL----- 57

Query: 65 QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI 96
           G I       G F+  + +FLIV   ++  +
Sbjct: 58 -GPI-----ALGRFLNALLNFLIVGTTVYFLV 83


>UniRef50_B3PMZ4 Large-conductance mechanosensitive channel, putative n=2
           Tax=Mycoplasma RepID=B3PMZ4_MYCA5
          Length = 152

 Score = 63.9 bits (154), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 66/124 (53%), Gaps = 1/124 (0%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           K+ ++   +GN+  LA+ V+IGAAFG +VSSL  D+IM  +  +      +   V     
Sbjct: 18  KDAKKSITKGNMFMLAIAVLIGAAFGAVVSSLANDVIMAAIAKIWNASSVEDLKVAGTIK 77

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTE 124
            G   A ++ + +    VF  L++ F+I  AI+   K  +   EP A P PT EE++L E
Sbjct: 78  IGKFLAALIQFVIVATVVFFTLLIVFSIKNAIEYA-KAKKMPIEPEAEPTPTNEELILAE 136

Query: 125 IRDL 128
           ++ L
Sbjct: 137 LKKL 140


>UniRef50_B5GFS7 Mechanosensitive channel n=12 Tax=Streptomyces RepID=B5GFS7_9ACTO
          Length = 194

 Score = 63.5 bits (153), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 44/139 (31%), Positives = 71/139 (51%), Gaps = 13/139 (9%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + + F+ F MRGNV+DLAV V+IGAAF  IV+++V  +I P +G   G  D  Q++  L 
Sbjct: 9   VWEGFKSFLMRGNVIDLAVAVVIGAAFTNIVNAVVKGVINPVVGAF-GTQDLDQYSYCLE 67

Query: 63  D----AQG--DIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRKKEEPAA 111
                A G  +   + + +G  +     FLI A  ++  +     + + +L  ++E    
Sbjct: 68  SPCVPAHGGEEAQGIQIMWGTVLSAALTFLITAAVVYFLMVLPMSRYLARLAARREAKYG 127

Query: 112 AP-APTKEEVLLTEIRDLL 129
            P  P  E  +L +IRD L
Sbjct: 128 TPEVPVSELDVLKDIRDEL 146


>UniRef50_B8DV17 Large conductance mechanosensitive channel protein n=4
           Tax=Bifidobacterium animalis subsp. lactis
           RepID=B8DV17_BIFA0
          Length = 166

 Score = 62.8 bits (151), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 47/147 (31%), Positives = 78/147 (53%), Gaps = 19/147 (12%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDF-KQFAVTL 61
           +I  F++F  RGN+VD+AVGV++GAA   +V+S+V  II P +  + G  D  K +  T+
Sbjct: 1   MIDGFKKFIARGNMVDMAVGVVMGAAVTAVVNSVVDGIINPLVAAIFGKPDLSKTWNWTI 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEE------------ 108
            +  G+    V+ +G  +  + +FL++A A++  I + IN L    E+            
Sbjct: 61  TNWAGE--NSVISFGSVLNALLNFLLIALAVYFCIVVPINNLRDMTEKAMAKVKGDDSDV 118

Query: 109 PAAAPAPTKEE---VLLTEIRDLLKEQ 132
            A  P  + EE   +LL +IR+ L  Q
Sbjct: 119 AAEEPDLSPEEQTVILLQDIRNALAAQ 145


>UniRef50_D2S4B1 Large conductance mechanosensitive channel protein n=1
           Tax=Geodermatophilus obscurus DSM 43160
           RepID=D2S4B1_9ACTO
          Length = 136

 Score = 62.4 bits (150), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 37/109 (33%), Positives = 62/109 (56%), Gaps = 7/109 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           +++  FR FA  G++VDLAVG+ IGAAF  +V SLV D+I+P +  + G  +F    +T+
Sbjct: 3   TLLTNFRNFAFSGSLVDLAVGLAIGAAFAAVVESLVGDVILPLVAAIFGAPNFDVLVLTV 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA 110
             AQ       + YG F+  +  FL++A  I + ++ I +   ++   A
Sbjct: 63  NGAQ-------IRYGSFLTALVSFLLLALTIMLLVQAIRRATGRETAGA 104


>UniRef50_C7QC56 Large conductance mechanosensitive channel protein n=1
           Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QC56_CATAD
          Length = 174

 Score = 61.2 bits (147), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 9/101 (8%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGI-DFKQFAVTLRDAQ 65
           F +F +RGNV+ LAVGV+IGAAF  +V+S     + P +G   GGI D+ +   TL    
Sbjct: 4   FVKFVVRGNVIGLAVGVVIGAAFAAMVTSFTTAFLTPLIGWATGGIGDYSKKVFTL---- 59

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRK 105
           G  P     YG F+     FL+ A  ++  I L +NKL  +
Sbjct: 60  GKTP---FPYGTFVNAGISFLLTAATLYFLIVLPVNKLTEE 97


>UniRef50_A5Z9U3 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
           ATCC 27560 RepID=A5Z9U3_9FIRM
          Length = 101

 Score = 61.2 bits (147), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 38/84 (45%), Positives = 50/84 (59%), Gaps = 12/84 (14%)

Query: 42  MPPLGLLIGGIDFKQFAV--------TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF 93
           MP + LL G IDF    +        TL +AQ    A  ++YG FI  + +FLI+AF +F
Sbjct: 1   MPVITLLTGKIDFSNLFIALDGGSYKTLAEAQ-KAGAATLNYGTFISGLINFLIMAFVVF 59

Query: 94  MAIKLINKLNRKKEEPAAAPAPTK 117
           M +K +NKL R+KEEP  APA TK
Sbjct: 60  MIVKFMNKL-RRKEEP--APATTK 80


>UniRef50_Q9P639 Related to large-conductance mechanosensitive channel n=8
           Tax=Leotiomyceta RepID=Q9P639_NEUCR
          Length = 373

 Score = 60.8 bits (146), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 36/126 (28%), Positives = 66/126 (52%), Gaps = 16/126 (12%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI--------------- 49
           ++F  FA +GNV+++A G+I+   F  +V+S V+DI++PP+ +L+               
Sbjct: 29  EDFVGFAFQGNVLEIAFGLILATMFTALVTSFVSDIVLPPISVLLPLNKNLEEKFAVLRS 88

Query: 50  GGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP 109
           G    ++   TL+ AQ D  AVVM YG F+  + +F+ V F+++    +   +++     
Sbjct: 89  GANHPEEGYNTLKQAQAD-GAVVMAYGFFMNRLLNFMGVGFSLYSIASIYQWMSKDPIIK 147

Query: 110 AAAPAP 115
              P P
Sbjct: 148 KTVPCP 153


>UniRef50_B8MJW8 Ion channel, putative n=3 Tax=Trichocomaceae RepID=B8MJW8_TALSN
          Length = 235

 Score = 60.8 bits (146), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 40/104 (38%), Positives = 62/104 (59%), Gaps = 19/104 (18%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL---IGGIDFKQFAV---- 59
           F +FAMR NV+++A+G++IG AF K+V+S V+D+I+P + LL      +D ++F+V    
Sbjct: 75  FVDFAMRDNVLEVAIGLMIGQAFTKVVTSFVSDVILPVISLLPFIHRNLD-EKFSVLRKG 133

Query: 60  ----------TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF 93
                     TL  A+ D  A+VM YG F+ NV  FL V   ++
Sbjct: 134 PNYDLAGGYNTLAQARDD-GALVMAYGAFLNNVMSFLGVGIVLY 176


>UniRef50_Q82H65 Putative mechanosensitive channel n=2 Tax=Streptomyces
           RepID=Q82H65_STRAW
          Length = 158

 Score = 60.8 bits (146), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 45/136 (33%), Positives = 74/136 (54%), Gaps = 9/136 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F+ F MRGNVVDLAV V+IGAAF  IV+S+V  II P +G   G  D  +++   R
Sbjct: 9   VLAGFKAFLMRGNVVDLAVAVVIGAAFTNIVNSVVKGIINPLVGAF-GTKDLDKYSSCFR 67

Query: 63  -----DAQGDIP-AVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEEPAAAPAP 115
                   G +   + + +G  + +   F+I A  ++  + L ++K   + E    A A 
Sbjct: 68  APCQVAKDGTVTKGIPIMWGTVLSSTLSFVITAAVVYFLMVLPMSKYLARMEARRKAKAG 127

Query: 116 TKEEVLLTEIRDLLKE 131
            +E + +TE++ +LKE
Sbjct: 128 MQEVIEVTELQ-VLKE 142


>UniRef50_A4RKI5 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
           RepID=A4RKI5_MAGGR
          Length = 175

 Score = 60.1 bits (144), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 37/108 (34%), Positives = 63/108 (58%), Gaps = 18/108 (16%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI---GGIDFKQFAV 59
           +   F +FA++GN++++A G+I+ AAF  I++SLV+DI++PPL +L      +D ++FAV
Sbjct: 32  VWDGFLDFALQGNILEIAFGLILAAAFTSIINSLVSDILLPPLSVLFPLNKNLD-EKFAV 90

Query: 60  -----TLRDAQGDIP---------AVVMHYGVFIQNVFDFLIVAFAIF 93
                    A G  P         AVVM +G F+  V +FL +  +++
Sbjct: 91  LKPGPNFDPANGGYPTIQLAQEDSAVVMAWGSFVNKVLNFLGLGVSLY 138


>UniRef50_D0L6D3 Large conductance mechanosensitive channel protein n=8
           Tax=Actinomycetales RepID=D0L6D3_GORB4
          Length = 274

 Score = 60.1 bits (144), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 48/143 (33%), Positives = 71/143 (49%), Gaps = 22/143 (15%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQ---FAV 59
           ++K FREF ++GNVV+LA  VI+G AF  IV++    I+ P +  +  G D  +   F +
Sbjct: 1   MLKGFREFILKGNVVELATAVIVGTAFTAIVTAFTTGIVEPIINSIPVGTDAAKGLGFQI 60

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLNR-----KKEEPAAAP 113
           T      D  +  +  G  I    +F+I+A  + F+ I   NKL       KK E     
Sbjct: 61  T------DKASTYVDIGAVITAFINFIIIAAVVYFLIIMPYNKLAELGGFGKKSE----- 109

Query: 114 APTKEEVLLTEIRDLLKEQNNRS 136
               E  LLTEIRDLL  + + +
Sbjct: 110 --VTEVALLTEIRDLLDPEGSSA 130


>UniRef50_A5KRR6 Large-conductance mechanosensitive channel-like protein n=1
           Tax=candidate division TM7 genomosp. GTL1
           RepID=A5KRR6_9BACT
          Length = 119

 Score = 60.1 bits (144), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 32/85 (37%), Positives = 53/85 (62%), Gaps = 2/85 (2%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGID-FKQFAVTLRDA 64
           +F  F     V  LAVG+++G A   +V SL+ +I+MPPLGL++G  +  K  +++L   
Sbjct: 17  DFMTFIREQGVAGLAVGLVLGGAVTVVVKSLIDNIVMPPLGLVLGSAEGLKGLSLSLGQT 76

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVA 89
                A V+HYGVF+ +V +F+++A
Sbjct: 77  AAGKDA-VLHYGVFLNDVVNFMVIA 100


>UniRef50_A1RBS3 Large conductance mechanosensitive channel protein n=7
           Tax=Actinomycetales RepID=A1RBS3_ARTAT
          Length = 154

 Score = 58.9 bits (141), Expect = 4e-08,   Method: Compositional matrix adjust.
 Identities = 43/137 (31%), Positives = 73/137 (53%), Gaps = 18/137 (13%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPL----GLLIGGIDFKQFAVT 60
           K F++F +RGNV++LA+ V+IG+AF  +V++   +II P +    G+   G+ FK +   
Sbjct: 3   KGFKDFILRGNVIELAIAVVIGSAFTALVTAFTNNIINPVIAAAGGMNADGLGFKIWE-- 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLN-----RKKEEPAAAPA 114
                 + PA +++ G  +  +  F+I A  + F+ +  +NK+N     R   E      
Sbjct: 61  ------NNPATLVNIGAVLTALVTFVITAAVVYFIFVAPMNKINSLVKDRLSTEEPEEEP 114

Query: 115 PTKEEVLLTEIRDLLKE 131
              +  LL EIRDLLK+
Sbjct: 115 LPADTALLAEIRDLLKD 131


>UniRef50_D1YYF3 Putative large-conductance mechanosensitive channel n=1
           Tax=Methanocella paludicola SANAE RepID=D1YYF3_METPS
          Length = 101

 Score = 58.2 bits (139), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 39/109 (35%), Positives = 61/109 (55%), Gaps = 12/109 (11%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-GGIDFKQFAV 59
           M I+++F+EF     V+ LAV  I+G A   ++ +LV DIIMP +G LI GG        
Sbjct: 1   MGIMQDFKEFLNEYKVMGLAVAFIMGVAATALIQALVNDIIMPIIGRLIPGG-------- 52

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI---NKLNRK 105
             + A  DI  ++  +G F+  V +F+I+AF +F+  K I    K+ +K
Sbjct: 53  AWQTATLDIAGMLFKWGDFLSQVINFVIIAFVVFLIAKFIMGEKKVTKK 101


>UniRef50_B8ZU13 Large-conductance mechanosensitive channel n=23 Tax=Mycobacterium
           RepID=MSCL_MYCLB
          Length = 154

 Score = 56.2 bits (134), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 42/132 (31%), Positives = 65/132 (49%), Gaps = 8/132 (6%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR-D 63
           + F+EF  RGN+VDLAV V+IG AF  +++     II P +  +  G++ +     LR D
Sbjct: 3   RGFKEFLSRGNIVDLAVAVVIGTAFTALITKFTDSIITPLINRV--GVNQQTNISPLRID 60

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT--KEEVL 121
             GD     +   + +    +FL++A  ++  + L     RK  E           + VL
Sbjct: 61  IGGD---QAIDLNIVLSAAINFLLIALVVYFLVVLPYTTIRKHGEVEQFDTDLIGNQVVL 117

Query: 122 LTEIRDLLKEQN 133
           L EIRDLL + N
Sbjct: 118 LAEIRDLLAQSN 129


>UniRef50_Q3D697 Large conductance mechanosensitive channel protein n=2
          Tax=Streptococcus agalactiae RepID=Q3D697_STRAG
          Length = 97

 Score = 56.2 bits (134), Expect = 3e-07,   Method: Compositional matrix adjust.
 Identities = 25/43 (58%), Positives = 34/43 (79%)

Query: 1  MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMP 43
          + +IKE +EF  +GNV+DLAV VI+GAAF  I++SLV D+I P
Sbjct: 21 VHMIKELKEFLFKGNVLDLAVAVILGAAFNAIITSLVKDVITP 63


>UniRef50_B4WRC7 Large conductance mechanosensitive channel protein n=1
           Tax=Synechococcus sp. PCC 7335 RepID=B4WRC7_9SYNE
          Length = 142

 Score = 54.3 bits (129), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 50/129 (38%), Positives = 73/129 (56%), Gaps = 14/129 (10%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPL---GLLIGGIDFKQFAVTL 61
            +F++F +RGNVV+LAV V++GAAF  IV+SLV DII P L    L   G+D     + L
Sbjct: 19  NDFKQFLLRGNVVELAVAVVLGAAFNAIVTSLVQDIITPVLLQPALRSAGVD----DIAL 74

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
             A G      + YGVF+  V +F++V   +F+ ++   + +R  EE A  P PT  E L
Sbjct: 75  LSAGG------VKYGVFLAAVINFIVVGLVLFLVVRTFARFSR-TEEAAIEPTPTPTEKL 127

Query: 122 LTEIRDLLK 130
              I+ L +
Sbjct: 128 DITIQHLTE 136


>UniRef50_Q0IDN4 Large conductance mechanosensitive channel protein n=2
           Tax=Synechococcus RepID=Q0IDN4_SYNS3
          Length = 127

 Score = 53.9 bits (128), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 39/129 (30%), Positives = 65/129 (50%), Gaps = 15/129 (11%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           +F+ F  +GNVVDLA+ V+I  AFGK+V+++V  ++   L   +   +         D+ 
Sbjct: 10  DFKAFINKGNVVDLAIAVVIAGAFGKVVATVVTLVMTNALEPALKAANV--------DSI 61

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA-AAPAPTKE-EVLLT 123
              PA     G  I  + +FL++AF  F+ +K I    RK+E  A   P P  +    +T
Sbjct: 62  NSWPA-----GTVIVAIINFLVIAFVCFLIVKSIEASKRKQEVIAETKPDPQAQLASAMT 116

Query: 124 EIRDLLKEQ 132
            + D L+ +
Sbjct: 117 RLTDALERK 125


>UniRef50_B8MKR4 Large-conductance mechanosensitive channel, putative n=1
           Tax=Talaromyces stipitatus ATCC 10500 RepID=B8MKR4_TALSN
          Length = 288

 Score = 52.8 bits (125), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 33/105 (31%), Positives = 56/105 (53%), Gaps = 19/105 (18%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGL--------------LIGGI 52
           F +FA+R NV+++A+G+II AAF K+V+S V+D+ +P + L              L  G 
Sbjct: 26  FWDFALRDNVLEVAIGLIIAAAFTKVVNSFVSDLFLPIISLLPFLNRNLEDKFAVLRKGK 85

Query: 53  DFKQFA----VTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF 93
            +  +      TL  A+ D  A+VM YG F+    +F+ +   ++
Sbjct: 86  HYSDWGPGGYNTLEQARDD-GALVMAYGAFLDKFINFVGIGLTLY 129


>UniRef50_A5GNA8 Large-conductance mechanosensitive channel n=1 Tax=Synechococcus
           sp. WH 7803 RepID=A5GNA8_SYNPW
          Length = 117

 Score = 52.8 bits (125), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 20/112 (17%)

Query: 4   IKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++EF EF   +GN ++LA+ V++G  F +IV+++  D++MP L  L+ G +++       
Sbjct: 1   MREFTEFFFQKGNALNLAIAVVVGTQFQQIVNAISKDLLMPLLNPLVRGGNWQNL----- 55

Query: 63  DAQGDIPAVVMHYG--VFIQNVFDF----LIVAFAIFMAIKLINKLNRKKEE 108
                   V+ +YG  + I  +FD     LIV +A+F  IK IN+  R  E 
Sbjct: 56  --------VIPYYGGDLAIGKIFDVILNSLIVGWALFFIIKAINRSQRTLES 99


>UniRef50_A5IYZ8 Large conductance mechanosensitive channel n=1 Tax=Mycoplasma
           agalactiae PG2 RepID=A5IYZ8_MYCAP
          Length = 140

 Score = 52.0 bits (123), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 64/124 (51%), Gaps = 19/124 (15%)

Query: 13  RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVV 72
           RGN++ LA+GV+IGA+F  ++SSL  D+IM  +  L        F V    A  ++ A  
Sbjct: 15  RGNMLLLAIGVLIGASFNAVISSLANDVIMAAIASL--------FNV---QAVSELKAGP 63

Query: 73  MHYGVFIQNVFDFLIVAFAIFMAIKL-------INKLNRKKEEP-AAAPAPTKEEVLLTE 124
           +  G F+  +  F+IVA  IF+ + L       +     KK  P     APT +E++L E
Sbjct: 64  VLIGKFLAALISFIIVALIIFLFLILYFLIKNAVEARKAKKNPPVVVVAAPTTDELILQE 123

Query: 125 IRDL 128
           ++ L
Sbjct: 124 LKKL 127


>UniRef50_D2ARQ8 Large conductance mechanosensitive channel protein n=9 Tax=Bacteria
           RepID=D2ARQ8_STRRD
          Length = 142

 Score = 52.0 bits (123), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 39/108 (36%), Positives = 62/108 (57%), Gaps = 14/108 (12%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI--GGIDFKQFAVTLRDA 64
           F++F MRGN+V+LAV V++GA F  +V +LV D+I P +  +   GG DF Q+  T+  A
Sbjct: 4   FKKFLMRGNLVELAVAVVVGATFSGLVQALVKDLITPLIAAITGGGGPDFSQYVFTVNGA 63

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRKKE 107
           +         YG FI ++  FLI+A  I+  +     ++I   +R K+
Sbjct: 64  K-------FMYGDFINHLLSFLIIAAVIYWLVVMPMTRVIAFFDRDKK 104


>UniRef50_A3Z5P9 Possible large-conductance mechanosensitive channel mscL n=1
           Tax=Synechococcus sp. RS9917 RepID=A3Z5P9_9SYNE
          Length = 102

 Score = 52.0 bits (123), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 34/102 (33%), Positives = 56/102 (54%), Gaps = 13/102 (12%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           +F++F  +GNVVDLAV V+IG AFGK+V ++V+        L++G I          D+ 
Sbjct: 10  DFKDFINKGNVVDLAVAVVIGGAFGKVVDAVVS--------LVMGNILEPVLKAANVDSI 61

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
              PA     G  I  + +FL++AF +F+ ++ I  + R  +
Sbjct: 62  AAWPA-----GSVIVALINFLVIAFVVFLIVRAIEAMRRSGD 98


>UniRef50_B6HL82 Pc21g07880 protein n=6 Tax=Trichocomaceae RepID=B6HL82_PENCW
          Length = 201

 Score = 51.6 bits (122), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 36/104 (34%), Positives = 59/104 (56%), Gaps = 19/104 (18%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGL---LIGGIDFKQFAV---- 59
           F  FA R NV+++A+G+II  AF K+V+S V D+++P + L   L   +D ++FAV    
Sbjct: 29  FINFAARDNVLEVALGLIIANAFTKVVTSFVTDMVLPIVSLLPFLNRNMD-QKFAVLSKG 87

Query: 60  ----------TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF 93
                     TL  A+ D  A+V+ YG F++   +FL V+  ++
Sbjct: 88  PNFDQQNGYNTLLQARED-GALVLAYGAFMETALNFLGVSLTLY 130


>UniRef50_B2VVD2 Putative uncharacterized protein n=1 Tax=Pyrenophora
           tritici-repentis Pt-1C-BFP RepID=B2VVD2_PYRTR
          Length = 242

 Score = 51.2 bits (121), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 39/112 (34%), Positives = 60/112 (53%), Gaps = 21/112 (18%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL---IGGIDFKQFA 58
           S  + F  FA+R NV+++AVG+I+ ++F    ++LV+DII+P + LL      +D K   
Sbjct: 25  SAWESFSNFALRDNVLEVAVGLILASSFTACANALVSDIILPIISLLPFLSRTLDTK--F 82

Query: 59  VTLRD---------------AQG-DIPAVVMHYGVFIQNVFDFLIVAFAIFM 94
           V LR                AQ  D  AVV+ YG F+  +  F IVA A+++
Sbjct: 83  VLLRHGPNSNSTISAGYNTPAQAVDDGAVVLAYGHFLDKIVRFAIVALALWV 134


>UniRef50_Q0CER3 Putative uncharacterized protein n=3 Tax=Aspergillus
            RepID=Q0CER3_ASPTN
          Length = 1384

 Score = 50.1 bits (118), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 41/129 (31%), Positives = 63/129 (48%), Gaps = 39/129 (30%)

Query: 7    FREFAMRGNVVDLAVGVI--------------------IGAAFGKIVSSLVADIIMPPLG 46
            F  FA R NV+++A+G++                    I  AF K+V+S V+DII+P + 
Sbjct: 1217 FVNFAARDNVLEVALGLMYLPPLPSLPPLPPVPLTQCSIAQAFTKVVTSFVSDIILPIIS 1276

Query: 47   LLI---GGIDFKQFAV--------------TLRDAQGDIPAVVMHYGVFIQNVFDFLIVA 89
            LL      +D ++FAV              TL  A+ D  A+V+ YGVF++ V  FL V+
Sbjct: 1277 LLPFLNRNMD-QKFAVLMAGPRYVEGEGYNTLTQARDD-GALVLAYGVFLETVLSFLGVS 1334

Query: 90   FAIFMAIKL 98
              ++   KL
Sbjct: 1335 VTLYAVAKL 1343


>UniRef50_A8N9V8 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
          okayama7#130 RepID=A8N9V8_COPC7
          Length = 209

 Score = 49.7 bits (117), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 22/42 (52%), Positives = 33/42 (78%)

Query: 7  FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL 48
          F  F +R NV+++AVG+I   AF K+V+SLV++II+PP+ LL
Sbjct: 39 FTAFVLRDNVLEVAVGLIFATAFTKLVTSLVSNIILPPISLL 80


>UniRef50_C9S828 Putative uncharacterized protein n=1 Tax=Verticillium albo-atrum
          VaMs.102 RepID=C9S828_VERA1
          Length = 129

 Score = 48.9 bits (115), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 21/42 (50%), Positives = 35/42 (83%)

Query: 7  FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL 48
          F +FAM+GN++++A G+I+ AAF  +V+S VA+I+MPPL ++
Sbjct: 30 FIDFAMQGNILEIAFGLILAAAFTGLVNSFVANILMPPLSVI 71


>UniRef50_UPI00017434B6 large conductance mechanosensitive channel protein n=1
          Tax=candidate division TM7 single-cell isolate TM7a
          RepID=UPI00017434B6
          Length = 79

 Score = 48.5 bits (114), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)

Query: 3  IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
          + KE R +  R      + G    + FGKIV+SLV DIIMP +G+++G IDF    + + 
Sbjct: 1  MFKELRNYIKRKCDGSCSWGYNW-SRFGKIVTSLVDDIIMPVIGIILGKIDFSNLKLVIT 59

Query: 63 DAQGDIPAVVMH 74
           A G  P   ++
Sbjct: 60 PASGSTPEAAVN 71


>UniRef50_D0P2C6 Large conductance mechanosensitive channel, putative n=2
           Tax=Phytophthora infestans T30-4 RepID=D0P2C6_PHYIN
          Length = 158

 Score = 48.1 bits (113), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 31/120 (25%), Positives = 62/120 (51%), Gaps = 7/120 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGV--IIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV 59
           +++ +F++F  +GN++D+A G    I  ++G     LVA + +  LG  +     K F +
Sbjct: 14  ALLTDFQDFIQQGNMIDMATGASPTITGSYGAQQLPLVAQVRLGRLGNKVPDNKMKAFVL 73

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEE 119
            ++D       V ++YG+F++N   F I A  +F+A+K + ++  K+        P  +E
Sbjct: 74  LVKDG-----VVTINYGLFMENAVTFFINAIFLFLAVKKVFEVVFKRSVLVKKQCPHCKE 128


>UniRef50_Q0I7U4 Large-conductive mechanosensitive channel n=2 Tax=Synechococcus
           RepID=Q0I7U4_SYNS3
          Length = 157

 Score = 48.1 bits (113), Expect = 9e-05,   Method: Compositional matrix adjust.
 Identities = 31/104 (29%), Positives = 57/104 (54%), Gaps = 11/104 (10%)

Query: 5   KEFREFA----MRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           + FREF      +GN ++LA+ V++G  F ++V +L  D++MP L  LI    ++++   
Sbjct: 42  RWFREFTDFFFQKGNALNLAIAVVVGTQFQQVVDALTQDLLMPLLNPLIRNGGWEEWV-- 99

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
           L  A G+     +  G  +  + + LIV + +F+ +K IN+  R
Sbjct: 100 LPYAGGE-----LLLGKAMNVLLNSLIVGWVLFLIVKAINRSQR 138


>UniRef50_C7PYG5 Large conductance mechanosensitive channel protein n=1
          Tax=Catenulispora acidiphila DSM 44928
          RepID=C7PYG5_CATAD
          Length = 145

 Score = 47.8 bits (112), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 34/92 (36%), Positives = 49/92 (53%), Gaps = 7/92 (7%)

Query: 7  FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQG 66
          FR+F +RGN+VDLAV V++G+ F  +V   VA  I P LG +    +F   + T+R    
Sbjct: 4  FRKFILRGNLVDLAVAVVVGSLFSSLVKQFVASFITPLLGTIGATPNFDHLSFTIRRH-- 61

Query: 67 DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL 98
                  YG F+   F F+I A  ++ AI L
Sbjct: 62 -----AFAYGAFLTEAFSFVIAAIVMYFAIVL 88


>UniRef50_A7I494 Large-conductance mechanosensitive channel-like protein n=3
           Tax=Genera incertae sedis RepID=A7I494_METB6
          Length = 125

 Score = 47.0 bits (110), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 39/107 (36%), Positives = 57/107 (53%), Gaps = 7/107 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M   +EF  F  +  V+ LAV  +IG A   +V++LV DIIMP + +L  G  + Q AV 
Sbjct: 25  MGFKEEFLLFLKQYQVIGLAVAFVIGTAATAMVNALVKDIIMPVVSVLTPGGQW-QTAVL 83

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
              A G I    +  G F+  V DFLI+A  +F  +K + K +  K+
Sbjct: 84  ---AVGPIN---LLAGDFLSAVLDFLIIALVVFFLVKYVMKGDVTKK 124


>UniRef50_A4F7T6 Large-conductance mechanosensitive channel n=3 Tax=Actinomycetales
           RepID=A4F7T6_SACEN
          Length = 158

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 44/133 (33%), Positives = 72/133 (54%), Gaps = 7/133 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F MRGNVVDLAV V++G+AF  +V++    II P +    GG       ++++
Sbjct: 1   MLKGFKDFLMRGNVVDLAVAVVVGSAFTALVTAFTTSIIKPVIAATGGG---NVTGLSIQ 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP--APTKEEV 120
              G+  +++  +   I  V  F I A  ++    L  K  +++ E       APT  E+
Sbjct: 58  LVAGNQQSII-DFAQVINAVITFFITAAVVYFIFVLPMKTLKERRERGKETEVAPTDVEL 116

Query: 121 LLTEIRDLLKEQN 133
           LL EIRDLL+ + 
Sbjct: 117 LL-EIRDLLRREQ 128


>UniRef50_Q2FQE0 Large conductance mechanosensitive channel protein n=4
           Tax=Euryarchaeota RepID=Q2FQE0_METHJ
          Length = 108

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 7/101 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M++I EF +F     VV LA+  I+G A   +V S V ++IMP + ++    D+K+  + 
Sbjct: 8   MTLISEFLDFLKEYKVVALAIAFIMGVAATALVKSFVDNLIMPFVSVITPSGDWKEAVLA 67

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
           +   Q  I       G F     +F+I+A  +FM  K + K
Sbjct: 68  IGPVQLGI-------GPFAAECINFIIIALVVFMVAKYVMK 101


>UniRef50_Q2IFL2 Large-conductance mechanosensitive channel-like n=1
           Tax=Anaeromyxobacter dehalogenans 2CP-C
           RepID=Q2IFL2_ANADE
          Length = 137

 Score = 46.2 bits (108), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 36/92 (39%), Positives = 50/92 (54%), Gaps = 11/92 (11%)

Query: 50  GGIDFKQFAVTLRDAQGDIPAV----------VMHYGVFIQNVFDFLIVAFAIFMAIKLI 99
           GG DFK + V LR+    +P            V  YG F+    +FLI+AF +F+ +K  
Sbjct: 47  GGFDFKDYFVALREIPPGVPRALDAMKKARVPVFAYGSFLTVALNFLILAFIVFLMVKQF 106

Query: 100 NKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKE 131
           N+L R+ E P   PAP +E VLL +IRD L+ 
Sbjct: 107 NRL-RRAEPPPPPPAPPEEVVLLRDIRDALRR 137


>UniRef50_D1J7K2 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           hominis ATCC 23114 RepID=D1J7K2_MYCHP
          Length = 172

 Score = 45.8 bits (107), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 20/136 (14%)

Query: 8   REFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGD 67
           ++   RGN+  LA+G+++GA+FG +VSSL  D+IM  +   +G  +   + V        
Sbjct: 21  KKIVSRGNMFMLAIGLLLGASFGALVSSLANDVIMSAITKAVGMKNLDAWVV-----WPG 75

Query: 68  IPAVVMHYGVFIQN----VFDFLIVAFAIFMAIKLI-----------NKLNRKKEEPAAA 112
           I A     G+FI      +  F+IV+  IF+ + ++            K N  +EE    
Sbjct: 76  IHATKETGGIFIGKFLGALIQFIIVSTFIFIGLMIVFTIKNSILYAKAKKNPIEEEIKEE 135

Query: 113 PAPTKEEVLLTEIRDL 128
           P PT EE++L E++ L
Sbjct: 136 PIPTTEELILNELKKL 151


>UniRef50_A5GSN0 Large-conductance mechanosensitive channel n=1 Tax=Synechococcus
          sp. RCC307 RepID=A5GSN0_SYNR3
          Length = 128

 Score = 45.1 bits (105), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 22/33 (66%), Positives = 27/33 (81%)

Query: 5  KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLV 37
          +EF +F  RGNVVDLAV VIIGAAF K+V ++V
Sbjct: 11 REFLDFINRGNVVDLAVAVIIGAAFTKVVQAVV 43


>UniRef50_UPI00016B2696 Large-conductance mechanosensitive channel n=1 Tax=candidate
           division TM7 single-cell isolate TM7c
           RepID=UPI00016B2696
          Length = 156

 Score = 44.7 bits (104), Expect = 9e-04,   Method: Compositional matrix adjust.
 Identities = 33/104 (31%), Positives = 55/104 (52%), Gaps = 6/104 (5%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR-DAQ 65
           F +F     V+ LAVG+ IG A G  V  LV   I P +  ++G  +  + AV+LR +  
Sbjct: 56  FMDFIREQGVIGLAVGLAIGTAAGDTVKKLVEGFISPIVQFIVGSKEGLE-AVSLRVEML 114

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL--INKLNRKKE 107
           G +      +G F+ +    +  AF I++ I L  +NKL+++K+
Sbjct: 115 GRVAE--FKWGAFVSSAITLVATAFVIYLIINLAKLNKLDKEKK 156


>UniRef50_C1AX17 Large-conductance mechanosensitive channel n=2 Tax=Rhodococcus
           RepID=C1AX17_RHOOB
          Length = 155

 Score = 44.3 bits (103), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 47/130 (36%), Positives = 71/130 (54%), Gaps = 8/130 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F +RGNV+DLAV V++GAAF  IV+S   ++I P + +  G  D       L 
Sbjct: 1   MLKGFKDFLLRGNVLDLAVAVVVGAAFTAIVTSFTNNVINPLIAVAGGANDLGWGYQIL- 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTK--EEV 120
               D PA  ++ G  I  V +F+I+A  ++    LI   N  K+     PA  K  E  
Sbjct: 60  ---ADNPATFINIGAVITAVINFVIIAAVVYFI--LIVPANAAKKRFITEPADKKASEAD 114

Query: 121 LLTEIRDLLK 130
           LL +IRD+L+
Sbjct: 115 LLIQIRDILE 124


>UniRef50_UPI0001B45932 large conductance mechanosensitive channel n=1 Tax=Mycobacterium
           intracellulare ATCC 13950 RepID=UPI0001B45932
          Length = 139

 Score = 43.5 bits (101), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 35/126 (27%), Positives = 60/126 (47%), Gaps = 11/126 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK F+ F MRG+V+ +A+G+++  AF  +V +    +I P +  +  G  F      L 
Sbjct: 1   MIKGFKSFVMRGDVITVAIGLVVALAFSNLVKAFTDSVINPLVAAVQPGTKFG-LGWQLG 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK-------EEPAA-APA 114
           DA     A  +  G FI  +  F++   A++  I +  K  + +       EEPA  A A
Sbjct: 60  DAGNK--ATFLDIGSFISAIIYFVVFMTAVYFMIVVPYKHIQARRGVTVFGEEPATKACA 117

Query: 115 PTKEEV 120
             K ++
Sbjct: 118 ECKSDI 123


>UniRef50_A7HMH6 Putative uncharacterized protein n=1 Tax=Fervidobacterium nodosum
          Rt17-B1 RepID=A7HMH6_FERNB
          Length = 61

 Score = 41.2 bits (95), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 18/40 (45%), Positives = 27/40 (67%)

Query: 4  IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMP 43
          +KEF +F  + NV+ LAV +IIG    + V+S V D++MP
Sbjct: 5  MKEFSDFLKQYNVIGLAVAIIIGGKLNQFVTSFVNDLLMP 44


>UniRef50_Q83MR6 Large-conductance mechanosensitive channel n=2 Tax=Tropheryma
          whipplei RepID=Q83MR6_TROWT
          Length = 207

 Score = 39.3 bits (90), Expect = 0.037,   Method: Compositional matrix adjust.
 Identities = 18/37 (48%), Positives = 26/37 (70%)

Query: 7  FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMP 43
          FR+F  R NVVDL+  V+IGAA   +++++V DI  P
Sbjct: 9  FRDFIARRNVVDLSAAVVIGAASTAVINAIVDDIFSP 45


>UniRef50_Q3AHC1 Large-conductive mechanosensitive channel n=1 Tax=Synechococcus sp.
           CC9605 RepID=Q3AHC1_SYNSC
          Length = 109

 Score = 39.3 bits (90), Expect = 0.038,   Method: Compositional matrix adjust.
 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 8/107 (7%)

Query: 3   IIKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           ++KEF +F   +GNV+ LA+ V++G     I  SL  D++MP +   I    +K  A+  
Sbjct: 4   LLKEFTDFFFTKGNVLALAIAVVVGDQVSAITKSLSTDLLMPLINPFIPHGSYKDLAIPY 63

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
                      +  G  +      ++VA+A+F+ I+   +  R  + 
Sbjct: 64  FGGP-------IAIGKVLDTFVSAMLVAWALFIIIQATKRFERISQR 103


>UniRef50_A1SES5 Large-conductance mechanosensitive channel n=1 Tax=Nocardioides sp.
           JS614 RepID=A1SES5_NOCSJ
          Length = 129

 Score = 38.9 bits (89), Expect = 0.053,   Method: Compositional matrix adjust.
 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 12/130 (9%)

Query: 7   FREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQG 66
           F+ F +RGN+V+LAV   + AA    V +    +IM  +G   G  DF  +         
Sbjct: 4   FKNFILRGNLVELAV-AFVMAAAFATVVTATVGLIMDLIGKAGGTPDFSDYVWN------ 56

Query: 67  DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTEIR 126
                 +  G ++  +  FLI+A  ++  I +     +++  P+  P   ++  LL EIR
Sbjct: 57  -----GISIGAWLTALISFLIIAAVVYFFIVVPYTKAKERYFPSPEPGTPEDVKLLEEIR 111

Query: 127 DLLKEQNNRS 136
           DLL  Q  RS
Sbjct: 112 DLLATQQGRS 121


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q48DU1 Large-conductance mechanosensitive channel n=45 ...   166   2e-40
UniRef50_B4S9H4 Large-conductance mechanosensitive channel n=23 ...   159   3e-38
UniRef50_A7GXI2 Large-conductance mechanosensitive channel n=4 T...   155   4e-37
UniRef50_B4RCK7 Large-conductance mechanosensitive channel n=31 ...   154   5e-37
UniRef50_A7I339 Large-conductance mechanosensitive channel n=28 ...   154   6e-37
UniRef50_A4IMP7 Large-conductance mechanosensitive channel n=13 ...   152   3e-36
UniRef50_C4K3W6 Mechanosensitive channel n=1 Tax=Candidatus Hami...   149   2e-35
UniRef50_A6WVY7 Large-conductance mechanosensitive channel n=26 ...   149   2e-35
UniRef50_Q2JLN5 Large-conductance mechanosensitive channel n=3 T...   149   3e-35
UniRef50_D2QT75 Large conductance mechanosensitive channel prote...   149   3e-35
UniRef50_B8G6C2 Large-conductance mechanosensitive channel n=7 T...   148   4e-35
UniRef50_C7JGJ5 Large-conductance mechanosensitive channel n=9 T...   147   1e-34
UniRef50_C3WUH2 Large-conductance mechanosensitive channel n=5 T...   146   3e-34
UniRef50_Q2G9Z8 Large-conductance mechanosensitive channel n=3 T...   145   4e-34
UniRef50_A6L685 Large-conductance mechanosensitive channel n=58 ...   144   6e-34
UniRef50_Q1LIC3 Large-conductance mechanosensitive channel n=26 ...   144   7e-34
UniRef50_C3J8B0 Large conductance mechanosensitive channel prote...   143   1e-33
UniRef50_Q5LGV7 Large-conductance mechanosensitive channel n=20 ...   139   2e-32
UniRef50_A1B4B3 Large-conductance mechanosensitive channel n=45 ...   139   2e-32
UniRef50_A2TYX0 Large-conductance mechanosensitive channel n=1 T...   139   3e-32
UniRef50_Q2NQQ0 Large-conductance mechanosensitive channel n=18 ...   138   4e-32
UniRef50_A0Q171 Large conductance mechanosensitive channel prote...   137   9e-32
UniRef50_Q3B3W2 Large-conductance mechanosensitive channel n=20 ...   137   1e-31
UniRef50_A4CIE9 Large-conductance mechanosensitive channel n=7 T...   136   2e-31
UniRef50_Q89ZV7 Large-conductance mechanosensitive channel n=9 T...   136   3e-31
UniRef50_A3MKN7 Large-conductance mechanosensitive channel n=286...   134   8e-31
UniRef50_C6WJF5 Large conductance mechanosensitive channel prote...   134   9e-31
UniRef50_Q034S0 Large-conductance mechanosensitive channel n=4 T...   134   1e-30
UniRef50_C9LNV3 Large conductance mechanosensitive channel prote...   134   1e-30
UniRef50_C1XQ99 Large conductance mechanosensitive channel prote...   133   1e-30
UniRef50_C0Z921 Large-conductance mechanosensitive channel n=36 ...   132   3e-30
UniRef50_A9VKI1 Large-conductance mechanosensitive channel n=72 ...   132   4e-30
UniRef50_Q3ANR9 Large-conductance mechanosensitive channel n=24 ...   131   6e-30
UniRef50_C4LHF9 Transport protein of the large conductance mecha...   130   1e-29
UniRef50_C2BQ59 MscL family large conductance mechanosensitive i...   128   5e-29
UniRef50_C8NCV5 Large conductance mechanosensitive channel prote...   128   8e-29
UniRef50_C0WF41 MscL family large conductance mechanosensitive i...   127   1e-28
UniRef50_B1YKK2 Large-conductance mechanosensitive channel n=2 T...   127   1e-28
UniRef50_D2EUH9 Large conductance mechanosensitive channel prote...   126   3e-28
UniRef50_D2LWQ6 Large conductance mechanosensitive channel prote...   124   6e-28
UniRef50_Q5NNP2 Large-conductance mechanosensitive channel n=5 T...   124   6e-28
UniRef50_Q03D91 Large-conductance mechanosensitive channel n=16 ...   123   1e-27
UniRef50_Q2JGX8 Large conductance mechanosensitive channel prote...   123   1e-27
UniRef50_UPI000196C3D3 hypothetical protein CATMIT_02956 n=1 Tax...   123   2e-27
UniRef50_C1RGF4 Large conductance mechanosensitive channel prote...   123   3e-27
UniRef50_C6XFL7 Large conductance mechanosensitive channel prote...   122   4e-27
UniRef50_C7MN86 Large conductance mechanosensitive channel prote...   121   6e-27
UniRef50_UPI0001C42BC0 large-conductance mechanosensitive channe...   121   8e-27
UniRef50_A6W442 Large conductance mechanosensitive channel prote...   121   9e-27
UniRef50_B0K2H2 Large conductance mechanosensitive channel prote...   121   1e-26
UniRef50_D0L6D3 Large conductance mechanosensitive channel prote...   120   1e-26
UniRef50_C5BZI9 Large conductance mechanosensitive channel prote...   120   1e-26
UniRef50_A9WMF7 Large-conductance mechanosensitive channel n=2 T...   120   1e-26
UniRef50_UPI000050F91C putative large-conductance mechanosensiti...   119   2e-26
UniRef50_A0M1G0 Large-conductance mechanosensitive channel n=10 ...   119   3e-26
UniRef50_B2GJ27 Large-conductance mechanosensitive channel n=5 T...   119   3e-26
UniRef50_A4CLF8 Large conductance mechanosensitive channel prote...   119   4e-26
UniRef50_C8W9F9 Large conductance mechanosensitive channel prote...   119   4e-26
UniRef50_Q6MD32 Putative mechanosensitive channel of large condu...   118   8e-26
UniRef50_UPI0000DB7E8B PREDICTED: hypothetical protein, partial ...   117   1e-25
UniRef50_B8DV17 Large conductance mechanosensitive channel prote...   117   1e-25
UniRef50_Q6AGE6 Large-conductance mechanosensitive channel n=7 T...   116   2e-25
UniRef50_D1BNK2 Large conductance mechanosensitive channel prote...   115   5e-25
UniRef50_Q2N8W2 Mechanosensitive channel n=1 Tax=Erythrobacter l...   114   6e-25
UniRef50_D1BCH3 Large conductance mechanosensitive channel prote...   114   8e-25
UniRef50_C8WNX6 Large conductance mechanosensitive channel prote...   114   8e-25
UniRef50_A6M387 Large-conductance mechanosensitive channel n=7 T...   114   1e-24
UniRef50_B9CMP0 Large conductance mechanosensitive channel prote...   114   1e-24
UniRef50_B5GFS7 Mechanosensitive channel n=12 Tax=Streptomyces R...   113   1e-24
UniRef50_Q7UW50 Probable large-conductance mechanosensitive chan...   113   1e-24
UniRef50_Q9RRR4 Large conductance mechanosensitive channel n=1 T...   113   2e-24
UniRef50_A3CM47 Large conductance mechano-sensitive ion channel,...   113   2e-24
UniRef50_B4D701 Large conductance mechanosensitive channel prote...   113   2e-24
UniRef50_D2R1B6 Large conductance mechanosensitive channel prote...   113   2e-24
UniRef50_A9HW97 Large-conductance mechanosensitive channel n=98 ...   113   2e-24
UniRef50_C4FGI6 Putative uncharacterized protein n=1 Tax=Bifidob...   112   4e-24
UniRef50_B4V9Z0 Mechanosensitive channel n=3 Tax=Streptomyces Re...   111   5e-24
UniRef50_A9KIC1 Large conductance mechanosensitive channel prote...   111   7e-24
UniRef50_A7X204 Large-conductance mechanosensitive channel n=51 ...   111   8e-24
UniRef50_B3DRI7 Large-conductance mechanosensitive channel n=17 ...   111   8e-24
UniRef50_A8LHK6 Large conductance mechanosensitive channel prote...   111   9e-24
UniRef50_C7MC43 Large conductance mechanosensitive channel prote...   111   1e-23
UniRef50_A0JZ24 Large conductance mechanosensitive channel prote...   111   1e-23
UniRef50_A7B9R5 Putative uncharacterized protein n=1 Tax=Actinom...   110   1e-23
UniRef50_Q82ZB4 Large-conductance mechanosensitive channel n=40 ...   110   1e-23
UniRef50_B8ZU13 Large-conductance mechanosensitive channel n=23 ...   110   2e-23
UniRef50_D0WJR5 Large conductance mechanosensitive channel prote...   110   2e-23
UniRef50_Q31LP8 Large-conductance mechanosensitive channel n=2 T...   109   2e-23
UniRef50_D2B464 Large conductance mechanosensitive channel prote...   109   2e-23
UniRef50_B0S3E4 Large-conductive mechanosensitive channel n=2 Ta...   109   3e-23
UniRef50_Q04FK1 Large-conductance mechanosensitive channel n=4 T...   109   3e-23
UniRef50_D2MPY5 Large conductance mechanosensitive channel prote...   108   4e-23
UniRef50_C5RAB3 MscL family large conductance mechanosensitive i...   108   4e-23
UniRef50_B0T274 Large-conductance mechanosensitive channel n=42 ...   108   6e-23
UniRef50_C0QYW6 Large-conductance mechanosensitive channel n=2 T...   107   7e-23
UniRef50_Q82H65 Putative mechanosensitive channel n=2 Tax=Strept...   107   7e-23
UniRef50_C7HUU0 Large conductance mechanosensitive channel prote...   106   2e-22
UniRef50_B5Y8I7 Large conductance mechanosensitive channel prote...   106   3e-22
UniRef50_A7VB12 Putative uncharacterized protein n=1 Tax=Clostri...   106   3e-22
UniRef50_A4AI90 Large-conductance mechanosensitive channel n=1 T...   106   3e-22
UniRef50_D1AZE9 Large conductance mechanosensitive channel prote...   105   3e-22
UniRef50_C4FVI2 Putative uncharacterized protein n=1 Tax=Catonel...   104   9e-22
UniRef50_Q1QDU6 Large-conductance mechanosensitive channel n=5 T...   104   1e-21
UniRef50_B2IVG3 Large conductance mechanosensitive channel prote...   102   2e-21
UniRef50_C6R3M2 Large conductance mechanosensitive channel prote...   102   3e-21
UniRef50_A5UVR8 Large-conductance mechanosensitive channel n=2 T...   102   3e-21
UniRef50_Q6AAH3 Large conductance mechanosensitive channel n=4 T...   102   5e-21
UniRef50_A4F7T6 Large-conductance mechanosensitive channel n=3 T...   102   5e-21
UniRef50_Q5SKL6 Large-conductance mechanosensitive channel n=2 T...   101   5e-21
UniRef50_C7H9Q8 Large conductance mechanosensitive channel prote...   101   7e-21
UniRef50_Q8DHB2 Large-conductive mechanosensitive channel n=1 Ta...   100   1e-20
UniRef50_A1RBS3 Large conductance mechanosensitive channel prote...   100   2e-20
UniRef50_B1XK85 Large conductance mechanosensitive channel prote...   100   2e-20
UniRef50_Q8EW76 Large-conductance mechanosensitive channel n=1 T...    99   2e-20
UniRef50_C9RJE4 Large conductance mechanosensitive channel prote...   100   3e-20
UniRef50_P73553 Large-conductance mechanosensitive channel n=2 T...    99   5e-20
UniRef50_C1AX17 Large-conductance mechanosensitive channel n=2 T...    98   9e-20
UniRef50_Q025U4 Large conductance mechanosensitive channel prote...    98   1e-19
UniRef50_B1V916 Putative large-conductance mechanosensitive chan...    97   1e-19
UniRef50_D0P2C5 Large Conductance Mechanosensitive Ion Channel (...    97   2e-19
UniRef50_Q2NK99 Large-conductance mechanosensitive channel n=2 T...    96   4e-19
UniRef50_C7QC56 Large conductance mechanosensitive channel prote...    95   5e-19
UniRef50_Q9P639 Related to large-conductance mechanosensitive ch...    94   1e-18
UniRef50_B3PMZ4 Large-conductance mechanosensitive channel, puta...    92   6e-18
UniRef50_B8MJW8 Ion channel, putative n=3 Tax=Trichocomaceae Rep...    91   1e-17
UniRef50_A6GYI6 Large-conductance mechanosensitive channel n=4 T...    91   1e-17
UniRef50_Q5HPJ2 Large-conductance mechanosensitive channel n=9 T...    87   1e-16
UniRef50_Q98B35 Large-conductance mechanosensitive channel n=1 T...    86   3e-16
UniRef50_D2S4B1 Large conductance mechanosensitive channel prote...    86   3e-16
UniRef50_UPI0001B45932 large conductance mechanosensitive channe...    86   4e-16
UniRef50_D1YYF3 Putative large-conductance mechanosensitive chan...    85   5e-16
UniRef50_A7HBZ5 Large conductance mechanosensitive channel prote...    85   8e-16
UniRef50_D2ARQ8 Large conductance mechanosensitive channel prote...    84   9e-16
UniRef50_C5BF23 Putative uncharacterized protein n=1 Tax=Edwards...    84   1e-15
UniRef50_Q0IDN4 Large conductance mechanosensitive channel prote...    83   3e-15
UniRef50_B3QZY1 Large-conductance mechanosensitive channel n=1 T...    83   3e-15
UniRef50_B8MKR4 Large-conductance mechanosensitive channel, puta...    83   4e-15
UniRef50_B6HL82 Pc21g07880 protein n=6 Tax=Trichocomaceae RepID=...    82   4e-15
UniRef50_A7I494 Large-conductance mechanosensitive channel-like ...    82   5e-15
UniRef50_Q6KH26 Large-conductance mechanosensitive channel n=1 T...    81   8e-15
UniRef50_A3Z5P9 Possible large-conductance mechanosensitive chan...    81   1e-14
UniRef50_A4RKI5 Putative uncharacterized protein n=1 Tax=Magnapo...    80   2e-14
UniRef50_Q0I7U4 Large-conductive mechanosensitive channel n=2 Ta...    79   4e-14
UniRef50_A5GNA8 Large-conductance mechanosensitive channel n=1 T...    79   4e-14
UniRef50_A5Z9U3 Putative uncharacterized protein n=1 Tax=Eubacte...    78   7e-14
UniRef50_D0P2C6 Large conductance mechanosensitive channel, puta...    78   7e-14
UniRef50_B2VVD2 Putative uncharacterized protein n=1 Tax=Pyrenop...    78   7e-14
UniRef50_D1J7K2 Large-conductance mechanosensitive channel n=1 T...    77   2e-13
UniRef50_Q2FQE0 Large conductance mechanosensitive channel prote...    76   2e-13
UniRef50_C7PYG5 Large conductance mechanosensitive channel prote...    75   6e-13
UniRef50_A8N9V8 Putative uncharacterized protein n=1 Tax=Coprino...    74   1e-12
UniRef50_UPI00017434B6 large conductance mechanosensitive channe...    74   1e-12
UniRef50_A5KRR6 Large-conductance mechanosensitive channel-like ...    73   3e-12
UniRef50_A5IYZ8 Large conductance mechanosensitive channel n=1 T...    73   3e-12
UniRef50_Q0CER3 Putative uncharacterized protein n=3 Tax=Aspergi...    71   1e-11
UniRef50_UPI00016B2696 Large-conductance mechanosensitive channe...    70   2e-11
UniRef50_Q2IFL2 Large-conductance mechanosensitive channel-like ...    69   3e-11
UniRef50_B4WRC7 Large conductance mechanosensitive channel prote...    68   9e-11
UniRef50_C9S828 Putative uncharacterized protein n=1 Tax=Vertici...    65   6e-10
UniRef50_Q3D697 Large conductance mechanosensitive channel prote...    60   2e-08
UniRef50_A5GSN0 Large-conductance mechanosensitive channel n=1 T...    54   2e-06

Sequences not found previously or not previously below threshold:

UniRef50_A1SES5 Large-conductance mechanosensitive channel n=1 T...    93   4e-18
UniRef50_Q83MR6 Large-conductance mechanosensitive channel n=2 T...    81   7e-15
UniRef50_Q3AHC1 Large-conductive mechanosensitive channel n=1 Ta...    63   2e-09
UniRef50_C1MQL7 Predicted protein n=1 Tax=Micromonas pusilla CCM...    58   1e-07
UniRef50_Q6SZN0 Putative uncharacterized protein (Fragment) n=1 ...    57   2e-07
UniRef50_UPI0000D52968 hypothetical protein P700755_20866 n=1 Ta...    56   3e-07
UniRef50_Q7NAU3 MscL n=1 Tax=Mycoplasma gallisepticum RepID=Q7NA...    55   9e-07
UniRef50_B1MYM2 Large-conductance mechanosensitive channel n=1 T...    53   2e-06
UniRef50_A7HMH6 Putative uncharacterized protein n=1 Tax=Fervido...    51   1e-05
UniRef50_Q0UYA9 Putative uncharacterized protein n=1 Tax=Phaeosp...    51   2e-05
UniRef50_A7E8P9 Predicted protein n=1 Tax=Sclerotinia sclerotior...    49   5e-05
UniRef50_C4Z968 Putative uncharacterized protein n=1 Tax=Eubacte...    49   5e-05
UniRef50_C1DYF1 Predicted protein n=1 Tax=Micromonas sp. RCC299 ...    46   3e-04
UniRef50_A7HMH7 Putative uncharacterized protein n=1 Tax=Fervido...    45   8e-04
UniRef50_Q03WP0 Large-conductance mechanosensitive channel n=2 T...    43   0.002
UniRef50_Q8PSE0 Large-conductance mechanosensitive channel n=1 T...    42   0.005
UniRef50_Q4A5X4 Putative uncharacterized protein n=2 Tax=Mycopla...    41   0.013
UniRef50_A4CR84 Protein-export membrane protein n=1 Tax=Synechoc...    39   0.067
UniRef50_B0PH06 Putative uncharacterized protein n=1 Tax=Anaerot...    38   0.071

>UniRef50_Q48DU1 Large-conductance mechanosensitive channel n=45 Tax=Bacteria
           RepID=MSCL_PSE14
          Length = 148

 Score =  166 bits (422), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 90/137 (65%), Positives = 112/137 (81%), Gaps = 1/137 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS++ EF+ FA++GNVVD+AVG+IIGAAFGKIVSS V D+IMPPLGLLIGG+DF   A+T
Sbjct: 1   MSVLSEFKAFAVKGNVVDMAVGIIIGAAFGKIVSSFVGDVIMPPLGLLIGGVDFSDLAIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK-EEPAAAPAPTKEE 119
           LR AQG  PAV++ YG FIQ V DF+IVAFAIFM +K IN+L R++ + P   P P+K+E
Sbjct: 61  LRPAQGTAPAVLLAYGKFIQTVIDFIIVAFAIFMGVKAINRLKREEAKAPTLPPTPSKQE 120

Query: 120 VLLTEIRDLLKEQNNRS 136
           VLL+EIRDLLKEQN  +
Sbjct: 121 VLLSEIRDLLKEQNKPA 137


>UniRef50_B4S9H4 Large-conductance mechanosensitive channel n=23 Tax=Bacteria
           RepID=MSCL_PROA2
          Length = 134

 Score =  159 bits (402), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 81/134 (60%), Positives = 105/134 (78%), Gaps = 1/134 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M  I+EF++FAMRGNVVDLAVG+IIG AFGK+V++LV  ++MPP+GLLIGG++F Q A  
Sbjct: 1   MGFIQEFKDFAMRGNVVDLAVGIIIGGAFGKVVTALVDGVLMPPIGLLIGGVNFDQLAFE 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-PAAAPAPTKEE 119
           LR A  +  AV ++YG F+Q + DF+I+AF+IF+ IK +N L RK EE P A P P+KEE
Sbjct: 61  LRAATAESAAVSLNYGAFLQTIVDFVIIAFSIFVVIKALNSLKRKSEEAPKAPPVPSKEE 120

Query: 120 VLLTEIRDLLKEQN 133
           VLL EIRDLLKE+ 
Sbjct: 121 VLLGEIRDLLKERG 134


>UniRef50_A7GXI2 Large-conductance mechanosensitive channel n=4 Tax=Bacteria
           RepID=MSCL_CAMC5
          Length = 133

 Score =  155 bits (392), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 79/133 (59%), Positives = 99/133 (74%), Gaps = 2/133 (1%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS I EF+EFAM+GNV+D+AVGV+IG AFGKIVSSLV DIIMP +G++ GG++F    +T
Sbjct: 1   MSFIGEFKEFAMKGNVLDMAVGVVIGTAFGKIVSSLVGDIIMPIVGVITGGVNFTDLKIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA--AAPAPTKE 118
           L+DA   +PAV ++YG FIQ   DFLI+AF IF  IK IN L RK  EP      AP ++
Sbjct: 61  LKDAAQGVPAVTINYGNFIQTAVDFLIIAFCIFCVIKAINSLKRKPAEPEVAQPAAPAED 120

Query: 119 EVLLTEIRDLLKE 131
            VLLT+IRDLLK+
Sbjct: 121 IVLLTQIRDLLKK 133


>UniRef50_B4RCK7 Large-conductance mechanosensitive channel n=31 Tax=Bacteria
           RepID=MSCL_PHEZH
          Length = 139

 Score =  154 bits (391), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 76/139 (54%), Positives = 95/139 (68%), Gaps = 5/139 (3%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSII EFREF  RGNV+DLAVGVIIGAAF  IV +LV +I+MPP+GL++ GIDF   A  
Sbjct: 1   MSIISEFREFIARGNVIDLAVGVIIGAAFNDIVKALVDNIVMPPIGLVLSGIDFSDLAWV 60

Query: 61  LRDAQGDIP---AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE--PAAAPAP 115
           L+      P   AV + YG FI     FLIVA+A+FM +KL+N + R++ E  P   PAP
Sbjct: 61  LKPDDPATPALDAVAIQYGAFINTCIRFLIVAWAVFMLVKLVNVIRRREAEKPPEEKPAP 120

Query: 116 TKEEVLLTEIRDLLKEQNN 134
           T +E LL EIRDLLK + +
Sbjct: 121 TPQETLLMEIRDLLKRRAD 139


>UniRef50_A7I339 Large-conductance mechanosensitive channel n=28 Tax=Bacteria
           RepID=MSCL_CAMHC
          Length = 132

 Score =  154 bits (391), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 77/132 (58%), Positives = 104/132 (78%), Gaps = 1/132 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS IKEF+EFA++GNV+D+AVGV+IG+AFGKIVSSLV D+IMP +G+L GG++F    +T
Sbjct: 1   MSFIKEFKEFAVKGNVIDMAVGVVIGSAFGKIVSSLVGDVIMPVVGVLTGGVNFTDLKIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR-KKEEPAAAPAPTKEE 119
           +++A G+  AV ++YG FIQ   DFLI+AF IF+AIK IN+L + +K+EP A   P  E 
Sbjct: 61  IKEAVGENAAVTINYGNFIQVTIDFLIIAFCIFLAIKAINQLKKPEKQEPKAPAEPNDEV 120

Query: 120 VLLTEIRDLLKE 131
            LL+EIRDLLK+
Sbjct: 121 KLLSEIRDLLKK 132


>UniRef50_A4IMP7 Large-conductance mechanosensitive channel n=13 Tax=Bacteria
           RepID=MSCL_GEOTN
          Length = 131

 Score =  152 bits (385), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 79/136 (58%), Positives = 97/136 (71%), Gaps = 11/136 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +  EF++FA+RGNV+DLAVGVIIG AFGKIVSSLV DIIMP +GLL+GGIDF   +  + 
Sbjct: 1   MWNEFKKFAIRGNVIDLAVGVIIGGAFGKIVSSLVNDIIMPLVGLLLGGIDFSNLSWKVG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL----NRKKEEPAAAPAPTKE 118
            A       V+ YG FIQ V DFLI+AF+IF+ +KLINKL     +++E     P  TKE
Sbjct: 61  KA-------VVKYGAFIQTVVDFLIIAFSIFLFVKLINKLYERVKKQEEMEETEPTLTKE 113

Query: 119 EVLLTEIRDLLKEQNN 134
           E LLTEIRDLLK+Q  
Sbjct: 114 EELLTEIRDLLKQQRE 129


>UniRef50_C4K3W6 Mechanosensitive channel n=1 Tax=Candidatus Hamiltonella defensa
           5AT (Acyrthosiphon pisum) RepID=C4K3W6_HAMD5
          Length = 150

 Score =  149 bits (378), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 86/150 (57%), Positives = 106/150 (70%), Gaps = 15/150 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS IKEFREFAMRGNV DLA+GVIIG+AFGK+VSSLVADIIMPP+GLLIGG+D KQF+  
Sbjct: 1   MSFIKEFREFAMRGNVADLAIGVIIGSAFGKVVSSLVADIIMPPIGLLIGGVDLKQFSFV 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR---------------K 105
           LR+A+ D+PAV+M+YG F+Q++ D +IV  AIF  IK +NKL R               K
Sbjct: 61  LREARNDVPAVIMNYGSFLQSLVDCIIVTLAIFSVIKFMNKLRRELEGILESRAEINKEK 120

Query: 106 KEEPAAAPAPTKEEVLLTEIRDLLKEQNNR 135
            E       P  +E+LL EIRDLLK+   +
Sbjct: 121 TEVGTQVEPPAPQEILLMEIRDLLKKSTKK 150


>UniRef50_A6WVY7 Large-conductance mechanosensitive channel n=26 Tax=Bacteria
           RepID=MSCL_OCHA4
          Length = 137

 Score =  149 bits (378), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 64/137 (46%), Positives = 93/137 (67%), Gaps = 7/137 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GN+VDLA+GVIIG AFG +V+S+V DIIMP +GL+ GGIDF    + L 
Sbjct: 1   MLKEFKEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLA 60

Query: 63  D------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT 116
                  A        + YG F+  + +FLI+A+ +F+ +K +N++ +K+E      AP 
Sbjct: 61  GEPRATLAAAREAGATIAYGNFVTLLINFLIIAWVLFLVVKGMNRMKKKEEAKPEPEAP- 119

Query: 117 KEEVLLTEIRDLLKEQN 133
           +EEVLLTEIRDLL +Q 
Sbjct: 120 REEVLLTEIRDLLAKQK 136


>UniRef50_Q2JLN5 Large-conductance mechanosensitive channel n=3 Tax=Bacteria
           RepID=MSCL_SYNJB
          Length = 132

 Score =  149 bits (377), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 68/133 (51%), Positives = 92/133 (69%), Gaps = 3/133 (2%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + ++EF+ F  RGN +DLAVGV+IG AFGKIV+S VAD+  P LGL+IGG++F+  A  +
Sbjct: 3   AFLEEFKNFISRGNALDLAVGVVIGGAFGKIVTSFVADLFTPVLGLMIGGVNFQHLAWEI 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
             +  D   V ++YG F+Q VFDF+I+AFAIF+ +K IN L RK+EE      P  E VL
Sbjct: 63  GGSPEDP--VTINYGSFLQAVFDFVIIAFAIFLLVKAINTLQRKEEESP-PTLPPPEVVL 119

Query: 122 LTEIRDLLKEQNN 134
           LTEIRD+L   + 
Sbjct: 120 LTEIRDILNRHSQ 132


>UniRef50_D2QT75 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=D2QT75_9SPHI
          Length = 163

 Score =  149 bits (377), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 75/141 (53%), Positives = 95/141 (67%), Gaps = 9/141 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFAMRGNV+DLAVGVIIGAAFGKIV S+V D+IMP +G+++G +DF    V L 
Sbjct: 1   MLKEFKEFAMRGNVMDLAVGVIIGAAFGKIVDSVVNDLIMPLVGMVVGNVDFSNLYVPLS 60

Query: 63  D--------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA-AP 113
           D        A       V  YG F+  V DFLI+AF IF+ I+ +N+L R K +     P
Sbjct: 61  DKITPGLALADARKLGPVFAYGSFLTIVIDFLILAFIIFLLIRGMNRLMRAKADTVDIPP 120

Query: 114 APTKEEVLLTEIRDLLKEQNN 134
           APTKEEVLLTEIRD L   ++
Sbjct: 121 APTKEEVLLTEIRDALVASSS 141


>UniRef50_B8G6C2 Large-conductance mechanosensitive channel n=7 Tax=Bacteria
           RepID=MSCL_CHLAD
          Length = 137

 Score =  148 bits (375), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 67/137 (48%), Positives = 86/137 (62%), Gaps = 7/137 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAVTL 61
           ++ EFR F  RGNV+DLAVGVIIGAAF  I++SLV DII P LGLL+GG  D   + + L
Sbjct: 1   MLNEFRTFINRGNVLDLAVGVIIGAAFTAIINSLVNDIINPLLGLLVGGRTDMSNYFLPL 60

Query: 62  RD------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
                   A+      V+ YG F+  V +FL+VAF IF+ ++  N+ N K  EP A P P
Sbjct: 61  AGQTATTLAEARAAGPVLAYGSFLNAVINFLLVAFVIFLIVRTANRFNPKPAEPPALPQP 120

Query: 116 TKEEVLLTEIRDLLKEQ 132
           T  E LL EIRDLL ++
Sbjct: 121 TPSERLLAEIRDLLAQR 137


>UniRef50_C7JGJ5 Large-conductance mechanosensitive channel n=9 Tax=Acetobacter
           RepID=C7JGJ5_ACEP3
          Length = 159

 Score =  147 bits (372), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 72/141 (51%), Positives = 90/141 (63%), Gaps = 8/141 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             + EFR F MRGNVVDLAVGVIIGAAF  IV+SLV DI  P +GLLIGGIDF    +TL
Sbjct: 12  GWVGEFRAFIMRGNVVDLAVGVIIGAAFTSIVNSLVKDIFNPLIGLLIGGIDFSNLFITL 71

Query: 62  R-------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN-RKKEEPAAAP 113
           +       +      AV ++ G+F+  V  FLIVA AIF  +K + +L+ R+ E+P A P
Sbjct: 72  KGPHLATLEEAQKAGAVTLNVGLFLNAVIQFLIVAMAIFWMVKALTRLHVREDEQPKAPP 131

Query: 114 APTKEEVLLTEIRDLLKEQNN 134
            P+K EVLL +IRD L   N 
Sbjct: 132 PPSKTEVLLEQIRDELAANNK 152


>UniRef50_C3WUH2 Large-conductance mechanosensitive channel n=5 Tax=Fusobacterium
           RepID=C3WUH2_9FUSO
          Length = 137

 Score =  146 bits (368), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 73/135 (54%), Positives = 94/135 (69%), Gaps = 1/135 (0%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            +++EF+ F MRGNVVD+AVGVII  AFGKIV+SLV DI MP +G LIG ++F    + L
Sbjct: 3   KLLEEFKAFVMRGNVVDMAVGVIIATAFGKIVASLVNDIFMPIIGALIGNMNFSDLQIKL 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-PAAAPAPTKEEV 120
                 +    + YG FIQ V +FLI+AF IF+ IK++  L +KKEE PA AP PTKEEV
Sbjct: 63  GTPVEGVEQAAIRYGAFIQEVINFLIIAFCIFVFIKVVTSLQKKKEEKPAPAPEPTKEEV 122

Query: 121 LLTEIRDLLKEQNNR 135
           LLTEIRD L +  ++
Sbjct: 123 LLTEIRDALNKMADK 137


>UniRef50_Q2G9Z8 Large-conductance mechanosensitive channel n=3 Tax=Sphingomonadales
           RepID=MSCL_NOVAD
          Length = 155

 Score =  145 bits (367), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 64/146 (43%), Positives = 87/146 (59%), Gaps = 13/146 (8%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           + ++ EF++F  RGNV+DLAVGVIIG AFGKIV+SL   +IMP +G L GG+DF ++ V 
Sbjct: 10  LGMLGEFKKFIARGNVLDLAVGVIIGGAFGKIVTSLTESVIMPVVGWLTGGVDFTRYFVR 69

Query: 61  LRDAQGDIPA-------------VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
           L     D                 ++ YG FI    +F+IVAF IF+ +K +N++  K E
Sbjct: 70  LGPVPADFKGDPTSYAELKAAGVPMIGYGDFITQAVNFVIVAFIIFLIVKAVNRMFEKPE 129

Query: 108 EPAAAPAPTKEEVLLTEIRDLLKEQN 133
           E  AAP+   E  LL EIRD LK + 
Sbjct: 130 EAPAAPSGPTEVELLAEIRDALKAKG 155


>UniRef50_A6L685 Large-conductance mechanosensitive channel n=58 Tax=Bacteria
           RepID=MSCL_BACV8
          Length = 146

 Score =  144 bits (365), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 85/141 (60%), Positives = 112/141 (79%), Gaps = 7/141 (4%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S +++F+ FAMRGNV+D+AVGVIIG AFGKIVSS+VAD+IMPP+GLL+GG++F    + L
Sbjct: 5   SFLQDFKAFAMRGNVIDMAVGVIIGGAFGKIVSSIVADVIMPPIGLLVGGVNFTDLKLQL 64

Query: 62  RDAQ----GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP---AAAPA 114
           + A+     +  AV ++YG F+Q  FDF+I+AF+IF+ I+L+ KLNRKKEE    AA PA
Sbjct: 65  KPAEVVDGVEKAAVTLNYGNFLQATFDFIIIAFSIFLFIRLLAKLNRKKEEVPAPAAPPA 124

Query: 115 PTKEEVLLTEIRDLLKEQNNR 135
           P+KEEVLLTEIRDLLKEQ  +
Sbjct: 125 PSKEEVLLTEIRDLLKEQAGK 145


>UniRef50_Q1LIC3 Large-conductance mechanosensitive channel n=26 Tax=Bacteria
           RepID=MSCL_RALME
          Length = 144

 Score =  144 bits (364), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 68/141 (48%), Positives = 88/141 (62%), Gaps = 10/141 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M ++ EF+ FAMRGNV+DLAVGVIIGAAFGKIV S+V D+IMP +G ++G +DF    V 
Sbjct: 1   MGMMSEFKTFAMRGNVIDLAVGVIIGAAFGKIVDSVVNDLIMPVIGRIVGKLDFSNMFVM 60

Query: 61  LRDAQGDIPAV----------VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA 110
           L D     P            V  YG F+  V +F+I+AF IFM ++  NK+  K+ EPA
Sbjct: 61  LADPPPGTPQTLDALKKAGVPVFAYGNFLTIVVNFVILAFIIFMMVRAFNKMREKEAEPA 120

Query: 111 AAPAPTKEEVLLTEIRDLLKE 131
           A     ++ VLL EIRD LK 
Sbjct: 121 APAVTPEDIVLLREIRDSLKA 141


>UniRef50_C3J8B0 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C3J8B0_9PORP
          Length = 142

 Score =  143 bits (362), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 74/140 (52%), Positives = 95/140 (67%), Gaps = 6/140 (4%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            ++ EF+EFAMRGNV+D+AVG+IIG AFGKIVSSLVAD+IMPP+ LL  G + +     L
Sbjct: 3   KLVSEFKEFAMRGNVMDMAVGIIIGGAFGKIVSSLVADVIMPPITLLTSGSNIEDLKWVL 62

Query: 62  RDAQGDI-----PAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR-KKEEPAAAPAP 115
           R+A  +      P V M  G F+Q V DF I+AF IFM IK +NKL + K EEPA    P
Sbjct: 63  REAVIEGGEITRPEVAMTVGTFLQAVLDFFIIAFVIFMLIKGMNKLRKAKPEEPATPAEP 122

Query: 116 TKEEVLLTEIRDLLKEQNNR 135
           + E  LL EI++LLK+Q  +
Sbjct: 123 SDEVKLLGEIKELLKKQAEK 142


>UniRef50_Q5LGV7 Large-conductance mechanosensitive channel n=20 Tax=Bacteria
           RepID=MSCL_BACFN
          Length = 146

 Score =  139 bits (352), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 84/142 (59%), Positives = 106/142 (74%), Gaps = 10/142 (7%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + +++F+ FAM+GNVVD+AVGVIIG AFGKIVSS+VADIIMPPLGLLIGG++F      +
Sbjct: 5   TFLQDFKAFAMKGNVVDMAVGVIIGGAFGKIVSSVVADIIMPPLGLLIGGVNFTDLKWVM 64

Query: 62  R------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK----EEPAA 111
           +      D +    AV ++YG F+Q  FDFLI+AF+IF+ IKLI KL +KK      P A
Sbjct: 65  KAAEYGADGKETAAAVTLNYGNFLQATFDFLIIAFSIFLFIKLITKLTQKKAEAPAAPPA 124

Query: 112 APAPTKEEVLLTEIRDLLKEQN 133
            PAPTKEE+LLTEIRDLLKE+ 
Sbjct: 125 PPAPTKEEILLTEIRDLLKEKQ 146


>UniRef50_A1B4B3 Large-conductance mechanosensitive channel n=45 Tax=Bacteria
           RepID=MSCL_PARDP
          Length = 145

 Score =  139 bits (352), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 67/145 (46%), Positives = 90/145 (62%), Gaps = 13/145 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + KEF+EF  RGNV+DLAVG+IIGAAF  IV+SLVAD+I P +GLL GG DF    + L+
Sbjct: 1   MFKEFKEFIARGNVIDLAVGIIIGAAFTAIVNSLVADLINPIIGLLTGGTDFSGHYLVLK 60

Query: 63  DAQG---------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN----RKKEEP 109
                        D  A V  YG F+  V +FLI+A+A+F+ +K +N++     R+KE  
Sbjct: 61  GEVPPGASLQVARDSGASVFAYGAFLSAVINFLIIAWAVFLLVKAVNRVQSAASRQKEAE 120

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQNN 134
           A A A   +E LLTEIRD L+ +  
Sbjct: 121 AEAAAGPTQEELLTEIRDELRARRT 145


>UniRef50_A2TYX0 Large-conductance mechanosensitive channel n=1 Tax=Polaribacter sp.
           MED152 RepID=A2TYX0_9FLAO
          Length = 138

 Score =  139 bits (351), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 61/139 (43%), Positives = 89/139 (64%), Gaps = 6/139 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV- 59
           M ++KEF++FAM+GN++D+AVG ++GAAF ++V+S    I+ P +GL+    DFK+    
Sbjct: 1   MGMLKEFKDFAMKGNLIDIAVGFVMGAAFKQVVTSFTGGIVSPLIGLIFEA-DFKKLKWV 59

Query: 60  ----TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
               TL DA   +  V + YG F+ NV DF+IVAF +FM +K IN   +K+E    AP  
Sbjct: 60  VKEGTLNDAGETVGQVAVLYGDFLTNVIDFIIVAFVMFMIVKGINATKKKEEPKPEAPKG 119

Query: 116 TKEEVLLTEIRDLLKEQNN 134
             +E LL +IRDLL +QN 
Sbjct: 120 PSQEELLEQIRDLLAKQNK 138


>UniRef50_Q2NQQ0 Large-conductance mechanosensitive channel n=18
           Tax=Gammaproteobacteria RepID=MSCL_SODGM
          Length = 144

 Score =  138 bits (349), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 77/101 (76%), Positives = 92/101 (91%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS +++FR+FAMRGNVVDLAVG+IIGAAFGKIVSSLVA++IMP LGLLIGGIDFKQF+  
Sbjct: 1   MSFLQKFRKFAMRGNVVDLAVGIIIGAAFGKIVSSLVANVIMPQLGLLIGGIDFKQFSWV 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
           L+ AQGD PAVVM YG+F+QN+FDF+IVAFA+F  IKLIN+
Sbjct: 61  LKPAQGDTPAVVMKYGIFLQNIFDFIIVAFAVFCIIKLINR 101


>UniRef50_A0Q171 Large conductance mechanosensitive channel protein n=6
           Tax=Clostridium RepID=A0Q171_CLONN
          Length = 138

 Score =  137 bits (346), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 77/134 (57%), Positives = 100/134 (74%), Gaps = 3/134 (2%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           IKEF+EFAM+GNV+DLAVGV+IG AFGKIVSSLV D+IMP +GL+ GGI+F    +TL+ 
Sbjct: 5   IKEFKEFAMKGNVLDLAVGVVIGGAFGKIVSSLVKDVIMPIIGLITGGINFTYLKITLKH 64

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN---RKKEEPAAAPAPTKEEV 120
             G+ P + ++ G FIQNV DF+I+AF+IFM IKLI+KL     ++E+      P+ E V
Sbjct: 65  GIGNKPPITLNIGNFIQNVVDFIIIAFSIFMFIKLISKLQIKKVEEEKEKEEETPSDEVV 124

Query: 121 LLTEIRDLLKEQNN 134
           LL EIRDLLK+ N 
Sbjct: 125 LLQEIRDLLKKDNK 138


>UniRef50_Q3B3W2 Large-conductance mechanosensitive channel n=20 Tax=Bacteria
           RepID=MSCL_PELLD
          Length = 161

 Score =  137 bits (345), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 58/145 (40%), Positives = 93/145 (64%), Gaps = 15/145 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNVVD+AVG+I+G AFG IV++LV++++MPPLGLL GG+DF    V ++
Sbjct: 1   MLKEFKEFALKGNVVDMAVGIIVGGAFGSIVNTLVSEVMMPPLGLLTGGVDFSNLYVVMK 60

Query: 63  DAQGDIP-----------AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA 111
           +     P           AV ++YG+F+  +  F I+AF++F+ +K IN+L +K +   A
Sbjct: 61  EGVEPGPYAALANARAAGAVTLNYGLFLNALVSFTIMAFSVFILVKAINRLRQKADAAPA 120

Query: 112 APAPTKEEVLLTEIRDLLKEQNNRS 136
            P+       LT    L+ +Q +R 
Sbjct: 121 PPSKKTCPYCLT----LVPQQASRC 141


>UniRef50_A4CIE9 Large-conductance mechanosensitive channel n=7 Tax=Bacteroidetes
           RepID=A4CIE9_9FLAO
          Length = 136

 Score =  136 bits (344), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 55/136 (40%), Positives = 84/136 (61%), Gaps = 6/136 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F M GNV+DLAV V++ +A G +VS  V DI+MP +G   GG+DF    + L 
Sbjct: 1   MLKEFKKFIMTGNVIDLAVAVLLASAIGLVVSGFVNDIMMPIVGYFTGGVDFSDMKIVLS 60

Query: 63  DA------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT 116
           +A        + P   + YG +I ++ + +IV F +FM +K  NK+ +K+E    AP   
Sbjct: 61  EAVVAADGTVEKPESAVRYGAWINSIINLIIVGFVLFMIVKSYNKVRKKEEPKPEAPKGP 120

Query: 117 KEEVLLTEIRDLLKEQ 132
            +E LL EIRDLLK++
Sbjct: 121 TQEDLLAEIRDLLKKK 136


>UniRef50_Q89ZV7 Large-conductance mechanosensitive channel n=9 Tax=Bacteria
           RepID=MSCL_BACTN
          Length = 148

 Score =  136 bits (342), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 81/144 (56%), Positives = 105/144 (72%), Gaps = 12/144 (8%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + +++F+ FAM+GNV+D+AVGV+IG AFGKIVSSLVA++IMPP+GLL+GG++F      +
Sbjct: 5   TFLQDFKAFAMKGNVIDMAVGVVIGGAFGKIVSSLVANVIMPPIGLLVGGVNFTDLKWVM 64

Query: 62  RDAQGD------IPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK------EEP 109
           + A+         PAV + YG F+Q  FDFLI+AFAIF+ I+LI KL  KK        P
Sbjct: 65  KAAEVGADGKEIAPAVSLDYGQFLQATFDFLIIAFAIFLFIRLITKLTTKKAAEEAPAAP 124

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQN 133
            A PAPTKEEVLLTEIRDLLKE+ 
Sbjct: 125 PAPPAPTKEEVLLTEIRDLLKEKK 148


>UniRef50_A3MKN7 Large-conductance mechanosensitive channel n=286 Tax=Bacteria
           RepID=MSCL_BURM7
          Length = 143

 Score =  134 bits (338), Expect = 8e-31,   Method: Composition-based stats.
 Identities = 67/145 (46%), Positives = 90/145 (62%), Gaps = 15/145 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSIIKEF+EFA++GNV+DLA+GVIIG AF KIV S+V D+IMP +G+L GG+DF    V 
Sbjct: 1   MSIIKEFKEFAVKGNVMDLAIGVIIGGAFSKIVDSVVKDLIMPVIGVLTGGLDFSNKFVL 60

Query: 61  LRDAQGDIPA-------------VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
           L                          YG FI  + +F+I+AF IF+ +K INKL + +E
Sbjct: 61  LGQIPASFKGNPESFKDLQAAGVATFGYGSFITVLINFIILAFIIFLMVKFINKLRKPEE 120

Query: 108 EPAAAPAPTKEEVLLTEIRDLLKEQ 132
             AA  A  ++ +LL EIRD LK++
Sbjct: 121 --AAPAATPEDVLLLREIRDSLKQR 143


>UniRef50_C6WJF5 Large conductance mechanosensitive channel protein n=4
           Tax=Actinomycetales RepID=C6WJF5_ACTMD
          Length = 176

 Score =  134 bits (337), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 6/135 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK F++F MRGNV+DLAV V+IGAAFG IV++   ++I P + L+ G  +   FAV L 
Sbjct: 1   MIKGFKDFLMRGNVIDLAVAVVIGAAFGSIVTAFTNNLINPLVALVGGMENPVGFAVQL- 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEEPAAA-PAPTKEEV 120
              G  P   M +G  +  V +F+I+A  I+    L +NK+  ++E    A P+   +  
Sbjct: 60  ---GASPKTTMDFGALVTAVMNFVIIAAVIYFVFVLPMNKIKERRERGQEAGPSEPTDVE 116

Query: 121 LLTEIRDLLKEQNNR 135
           LL EIRDL+  Q ++
Sbjct: 117 LLKEIRDLMVAQASQ 131


>UniRef50_Q034S0 Large-conductance mechanosensitive channel n=4 Tax=Lactobacillus
           casei group RepID=MSCL_LACC3
          Length = 123

 Score =  134 bits (337), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 59/132 (44%), Positives = 82/132 (62%), Gaps = 10/132 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F MRGNV+DLAVGVIIG+AF  +V+SL  ++I P L +  G  D      T+ 
Sbjct: 1   MLKEFQKFIMRGNVLDLAVGVIIGSAFTGLVTSLTKNLINPILSMFAGKADLSGLYFTIL 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
            A+         YG FI +V +FLI+AF +F+ +K IN++   K    A PA   +E LL
Sbjct: 61  GAK-------FTYGNFINDVLNFLIIAFVVFLLVKGINRILPSK---PAKPAGPTQEELL 110

Query: 123 TEIRDLLKEQNN 134
           TEIRDLLK+   
Sbjct: 111 TEIRDLLKQDQQ 122


>UniRef50_C9LNV3 Large conductance mechanosensitive channel protein n=1
           Tax=Dialister invisus DSM 15470 RepID=C9LNV3_9FIRM
          Length = 168

 Score =  134 bits (337), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 56/128 (43%), Positives = 84/128 (65%), Gaps = 7/128 (5%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M ++KEFR+FA+RGNVVD+AVGV+IG AFGKI+SSLV +IIMPP+G+++GG+DF    + 
Sbjct: 23  MGMMKEFRDFAVRGNVVDMAVGVVIGGAFGKIISSLVENIIMPPIGMIMGGVDFSNRFIN 82

Query: 61  LRDA-------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
           L            ++   V+ YG F+  + DFLI+AF IF+ ++ +N+   K+E   A  
Sbjct: 83  LGKTPVATLAEAKEMNVPVIAYGQFLNTIIDFLIIAFVIFLVVRQMNRAFPKEEAAPART 142

Query: 114 APTKEEVL 121
               +E +
Sbjct: 143 CQFCKEPI 150


>UniRef50_C1XQ99 Large conductance mechanosensitive channel protein n=1
           Tax=Meiothermus silvanus DSM 9946 RepID=C1XQ99_9DEIN
          Length = 132

 Score =  133 bits (336), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 59/134 (44%), Positives = 79/134 (58%), Gaps = 8/134 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +++ FR+F +RGNVVDLAV VIIG AFG +V S+V DII P +GL+ G  DF    +   
Sbjct: 1   MLQGFRDFILRGNVVDLAVAVIIGTAFGAVVDSMVKDIITPIIGLIGGQPDFANLRL-FA 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK----LNRKKEEPAAAPAPTKE 118
           DA+G      + YG F+  V  F I A  +++ I L  K    + +K + P    AP + 
Sbjct: 60  DAKGQGG---IAYGSFLNAVISFFIKAAVVYLVIVLPMKRMVEMLKKPQAPEIPAAPPEN 116

Query: 119 EVLLTEIRDLLKEQ 132
            VLL EIRDLLK Q
Sbjct: 117 VVLLREIRDLLKAQ 130


>UniRef50_C0Z921 Large-conductance mechanosensitive channel n=36 Tax=Bacteria
           RepID=MSCL_BREBN
          Length = 154

 Score =  132 bits (333), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 60/123 (48%), Positives = 84/123 (68%), Gaps = 8/123 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNV+DLAVGV+IG AFGKIV+SLV DII P +GLL+G +DF    + L 
Sbjct: 1   MLKEFKEFALKGNVMDLAVGVVIGGAFGKIVTSLVNDIITPLIGLLLGKVDFSGLFINLS 60

Query: 63  D-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
                         A  ++YG+F+ +V DF+I+AF+IF+ IK +N+  RK +E   AP  
Sbjct: 61  GVPYKTIAEAKTAHAATLNYGLFLNSVIDFVIIAFSIFIVIKQLNRFKRK-QEVEQAPVT 119

Query: 116 TKE 118
           TKE
Sbjct: 120 TKE 122


>UniRef50_A9VKI1 Large-conductance mechanosensitive channel n=72 Tax=Bacillus
           RepID=MSCL_BACWK
          Length = 133

 Score =  132 bits (332), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 73/136 (53%), Positives = 96/136 (70%), Gaps = 10/136 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +  EF++FA +GNV+DLAVGV+IGAAFGKIVSSLV DII P LG+++GG++F    +T  
Sbjct: 1   MWNEFKKFAFKGNVIDLAVGVVIGAAFGKIVSSLVKDIITPLLGMVLGGVNFTDLKLTFG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK---EEPAAAPAPTKEE 119
            +        + YG FIQ +FDFLI+A AIFM +K+ NKL  K+   E+    P PTKEE
Sbjct: 61  KSS-------IMYGNFIQTIFDFLIIAAAIFMFVKVFNKLTSKREEEEKKEELPEPTKEE 113

Query: 120 VLLTEIRDLLKEQNNR 135
            +L EIRDLLK+QN+ 
Sbjct: 114 EILGEIRDLLKQQNSS 129


>UniRef50_Q3ANR9 Large-conductance mechanosensitive channel n=24 Tax=Bacteria
           RepID=MSCL_CHLCH
          Length = 155

 Score =  131 bits (331), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 62/129 (48%), Positives = 90/129 (69%), Gaps = 12/129 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS++KEF+EFA++GNVVD+AVG+IIG AFG IV++LV+ +I+PPLGLLIGG+DF    + 
Sbjct: 1   MSVMKEFKEFAVKGNVVDMAVGIIIGGAFGAIVNNLVSQVILPPLGLLIGGVDFSSLYII 60

Query: 61  LRDA------------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
           L++                  AV ++YGVF+ +VF F+I+AFA+F+ +K IN L R +  
Sbjct: 61  LKEGATQAAPYNSLAEATAAGAVTLNYGVFLNSVFSFVIMAFAVFLLVKSINMLRRTEGS 120

Query: 109 PAAAPAPTK 117
            +A PAP+ 
Sbjct: 121 KSAVPAPST 129


>UniRef50_C4LHF9 Transport protein of the large conductance mechanosensitive ion
           channel family n=4 Tax=Corynebacterineae
           RepID=C4LHF9_CORK4
          Length = 187

 Score =  130 bits (328), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 47/138 (34%), Positives = 71/138 (51%), Gaps = 8/138 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K FR+F MRGNV++LA+ V+IG+AF  IV++    II P +    GG +   +   L 
Sbjct: 1   MLKGFRDFIMRGNVIELAMAVVIGSAFTAIVTAFTKYIINPLIA-CFGGANTDGWGFRL- 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKL---NRKKEEPAAAPAPTKE 118
                     + +G  +  V +FLI+A  ++  +   +NKL    +K         P  E
Sbjct: 59  --IRGNEKTFLDFGSVLTAVINFLIIAAVVYFILVAPMNKLEEIRKKHMGVKEEEVPVTE 116

Query: 119 EVLLTEIRDLLKEQNNRS 136
           + LL EIRDLL  QN  S
Sbjct: 117 KDLLLEIRDLLAAQNQVS 134


>UniRef50_C2BQ59 MscL family large conductance mechanosensitive ion channel n=2
           Tax=Corynebacterium RepID=C2BQ59_9CORY
          Length = 167

 Score =  128 bits (323), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 55/138 (39%), Positives = 77/138 (55%), Gaps = 11/138 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           ++++K F++F MRGNV++LA  VIIG+AF  IV S+   II P +  L G  +       
Sbjct: 3   ITMLKGFKDFIMRGNVIELATAVIIGSAFTAIVKSVTDSIIQPIINSL-GSAEVGAVGFH 61

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK-LINKL----NRKKEEPAAAPAP 115
           + DA+       + +G  I    +FLI+A  ++  I   INKL     R+      APAP
Sbjct: 62  ITDAE----NTFVDFGAVISAAINFLIIAAVVYFLIVMPINKLTEAAKRRHGVDPEAPAP 117

Query: 116 TKEEVLLTEIRDLLKEQN 133
           T EE LL EIRDLL+ QN
Sbjct: 118 TSEE-LLAEIRDLLEAQN 134


>UniRef50_C8NCV5 Large conductance mechanosensitive channel protein n=1
           Tax=Cardiobacterium hominis ATCC 15826
           RepID=C8NCV5_9GAMM
          Length = 143

 Score =  128 bits (321), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 58/139 (41%), Positives = 80/139 (57%), Gaps = 6/139 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F+ F  RGNVVDLAVGV++GAAFG +VS LV   I P +  L+G  +F     +L 
Sbjct: 1   MLSGFKTFIARGNVVDLAVGVVMGAAFGLVVSGLVESFINPLIAWLVGKPNFDSLMFSLP 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF-MAIKLINKLN---RKKEEPAAAPAPTKE 118
              G+ P  V  YG  +  + +F +V+ AI+   I  +NKL    +KKEE  A PAP  E
Sbjct: 61  PLIGEEP-TVFQYGKILTAIVNFFLVSLAIYIFIIIPMNKLTASMKKKEEVEAPPAPPSE 119

Query: 119 EV-LLTEIRDLLKEQNNRS 136
           E+ LL EIRD L  +   +
Sbjct: 120 EILLLREIRDSLAVRRAAA 138


>UniRef50_C0WF41 MscL family large conductance mechanosensitive ion channel n=2
           Tax=Corynebacterium RepID=C0WF41_9CORY
          Length = 165

 Score =  127 bits (319), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 53/139 (38%), Positives = 77/139 (55%), Gaps = 11/139 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F MRGNVV+LA  VIIG+AF  IV+S+   II P +    G  +       + 
Sbjct: 1   MLKGFKDFIMRGNVVELATAVIIGSAFTAIVTSVTDSIIQPIINS-FGSAEVDGLGFQIT 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK-LINKL----NRKKEEPAAAPAPTK 117
               D  + ++ +G  I    +FLI+A  ++  I   +NKL     R++     APAPT 
Sbjct: 60  ----DNKSTLVDFGAVITAAINFLIIAAVVYFLIVMPLNKLTEASKRRQGVDPEAPAPTS 115

Query: 118 EEVLLTEIRDLLKEQNNRS 136
           EE LL EIRDLL+ QN  +
Sbjct: 116 EE-LLAEIRDLLQAQNADA 133


>UniRef50_B1YKK2 Large-conductance mechanosensitive channel n=2 Tax=Bacillales
           RepID=MSCL_EXIS2
          Length = 129

 Score =  127 bits (319), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 66/132 (50%), Positives = 87/132 (65%), Gaps = 7/132 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + K F+EFA RGNV+DLAVGVI+GAAF  I+ SLV  I MP +G++IGGID K  +V + 
Sbjct: 1   MFKAFKEFAFRGNVIDLAVGVILGAAFSGIIKSLVDSIFMPLIGIIIGGIDVKGLSVEVG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
           +A        + YG F+Q   +F+++AFA+F+ +K IN   RK+E      APT EE LL
Sbjct: 61  NAN-------LLYGQFLQASIEFILIAFALFLFVKGINAFRRKEETTEEVAAPTTEEKLL 113

Query: 123 TEIRDLLKEQNN 134
           TEIRD L  Q N
Sbjct: 114 TEIRDALVRQQN 125


>UniRef50_D2EUH9 Large conductance mechanosensitive channel protein n=8
           Tax=Bacteroidales RepID=D2EUH9_9BACE
          Length = 144

 Score =  126 bits (316), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 82/140 (58%), Positives = 105/140 (75%), Gaps = 9/140 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S ++EF+ FAM+GNV+D+AVGVIIG AFGKIVSS+VAD+IMPP+GLL+GG++F      L
Sbjct: 5   SFLQEFKAFAMKGNVIDMAVGVIIGGAFGKIVSSIVADVIMPPIGLLVGGVNFTDLKWVL 64

Query: 62  RDAQ----GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN-----RKKEEPAAA 112
           + A+     +I AV ++YG F+Q  FDFLI+AF+IFM IKL+ KL           P A 
Sbjct: 65  KPAEMVDGKEIAAVTLNYGNFLQVTFDFLIIAFSIFMFIKLLTKLTEKKKEEAPAAPPAP 124

Query: 113 PAPTKEEVLLTEIRDLLKEQ 132
           PAP+KEEVLLTEIRDLLKE+
Sbjct: 125 PAPSKEEVLLTEIRDLLKEK 144


>UniRef50_D2LWQ6 Large conductance mechanosensitive channel protein n=1 Tax=Bacillus
           cellulosilyticus DSM 2522 RepID=D2LWQ6_BACS4
          Length = 164

 Score =  124 bits (313), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 53/115 (46%), Positives = 75/115 (65%), Gaps = 7/115 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS  + FREFA+RGNVVD+ +GVIIGAAFG IV+S V+D++MPP+GLL+G ++F    + 
Sbjct: 1   MSFFRGFREFAIRGNVVDMGIGVIIGAAFGGIVTSFVSDVLMPPIGLLLGKVNFSNLYIN 60

Query: 61  LRD-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
           L            +  A  ++YG FI+ V  F+I+AFA ++ I  +NKL R   E
Sbjct: 61  LSGEHYSSLAEAQEAGAATVNYGAFIETVIHFVIIAFAAYLIIIQMNKLRRVPME 115


>UniRef50_Q5NNP2 Large-conductance mechanosensitive channel n=5
           Tax=Sphingomonadaceae RepID=MSCL_ZYMMO
          Length = 154

 Score =  124 bits (313), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 60/154 (38%), Positives = 85/154 (55%), Gaps = 21/154 (13%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSI+ +F+ F  +GNV+ L + VI+G AF KI+SS+  D++MP +G + GG+DF  F + 
Sbjct: 1   MSILTDFKNFISKGNVLGLGIAVIMGDAFNKIISSVTGDLLMPIIGAVFGGVDFSGFFIR 60

Query: 61  LRDAQGDIPAV-------------VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR--- 104
           L                       +  YG F+  V +F+IVAF +FM +KL  KL +   
Sbjct: 61  LGAVPAGYTGSLTSYNDLKKAGVPLFGYGQFLTVVVNFVIVAFILFMIMKLAAKLQKELD 120

Query: 105 ----KKEEPAAAPAPTKEE-VLLTEIRDLLKEQN 133
               KKEE  A  APT E+ VLL EIRD L+ + 
Sbjct: 121 KTEAKKEEKIAEAAPTPEDIVLLREIRDELRGKK 154


>UniRef50_Q03D91 Large-conductance mechanosensitive channel n=16 Tax=Bacteria
           RepID=MSCL_PEDPA
          Length = 140

 Score =  123 bits (310), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 62/129 (48%), Positives = 79/129 (61%), Gaps = 9/129 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EF  RGNV+DLAVGVIIG AF  IV SLV  +I P +GL IGGIDF  + +   
Sbjct: 1   MLKEFKEFVSRGNVLDLAVGVIIGGAFTSIVKSLVNYLINPLIGLFIGGIDFSDWVL--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE--EV 120
                +      +G FI  V +FLI+AF +F+ +KL+NK   KKEE     A   E  E+
Sbjct: 58  ----KVAGATFKFGSFINAVINFLIIAFVVFILVKLVNKFLPKKEEQEDDEAEAIENSEI 113

Query: 121 LLTEIRDLL 129
            L EIRD L
Sbjct: 114 YLKEIRDAL 122


>UniRef50_Q2JGX8 Large conductance mechanosensitive channel protein n=3 Tax=Frankia
           RepID=Q2JGX8_FRASC
          Length = 131

 Score =  123 bits (310), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 57/134 (42%), Positives = 70/134 (52%), Gaps = 12/134 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K FR+F MRGNVVDLAV V++G AF  +V+SLV  I  P +  + G  DF     T   
Sbjct: 1   MKGFRQFLMRGNVVDLAVAVMVGTAFTAVVTSLVKTIFTPLIAAIFGKPDFSALTFT--- 57

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-----NKLNRKKEEPAAAPAPTKE 118
               I   V  YG FI +V  FL VA  I+  + L       +  R +  P   PA T E
Sbjct: 58  ----INGSVFRYGEFINSVIAFLSVATVIYFVVVLPLNTINERRTRGQVPPEEDPALTDE 113

Query: 119 EVLLTEIRDLLKEQ 132
             LLTEIRDLL E 
Sbjct: 114 ARLLTEIRDLLAEH 127


>UniRef50_UPI000196C3D3 hypothetical protein CATMIT_02956 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196C3D3
          Length = 130

 Score =  123 bits (309), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 59/134 (44%), Positives = 87/134 (64%), Gaps = 8/134 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            +  EF+EFA +GNV+D+AVGVI+G A   +V+SLV DIIMP L  +I      +    +
Sbjct: 3   KLWNEFKEFAFKGNVIDMAVGVILGTAITAVVTSLVQDIIMPVLSAII------KIPSDI 56

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK-LNRKKEEPAAAPAPTKEEV 120
            +    +  + + YG F+ N+ +FL++AF IF+ IK INK ++ +K+E  A PAP  E++
Sbjct: 57  TELTLKVNNINIKYGSFLSNLINFLLMAFCIFICIKAINKVMSFRKKEEEAVPAPKPEDI 116

Query: 121 -LLTEIRDLLKEQN 133
            LL EIRDLLKE+ 
Sbjct: 117 ALLEEIRDLLKEKK 130


>UniRef50_C1RGF4 Large conductance mechanosensitive channel protein n=1
           Tax=Cellulomonas flavigena DSM 20109 RepID=C1RGF4_9CELL
          Length = 201

 Score =  123 bits (308), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 6/137 (4%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQF---A 58
            + + F++F  RGN ++LAVGV++GAAF  +VS+L    I P +G + G  +        
Sbjct: 30  KVFQGFKDFISRGNAIELAVGVVVGAAFTSVVSALQDAFINPLIGWIFGKPNLDNLWNIG 89

Query: 59  VTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKL--NRKKEEPAAAPAP 115
               + +    A  +  GV +  +  FLI A AI+  I L +N L   RK+       AP
Sbjct: 90  PYTWNEEIAAEATPIQVGVILSALLQFLITAAAIYFLIVLPLNALAARRKQGVEEEPAAP 149

Query: 116 TKEEVLLTEIRDLLKEQ 132
            ++ +LL EIRDLL ++
Sbjct: 150 AEDILLLQEIRDLLSQR 166


>UniRef50_C6XFL7 Large conductance mechanosensitive channel protein n=1
           Tax=Candidatus Liberibacter asiaticus str. psy62
           RepID=C6XFL7_LIBAP
          Length = 141

 Score =  122 bits (307), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 54/138 (39%), Positives = 82/138 (59%), Gaps = 11/138 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG-GIDFKQFAVTL 61
           +  EF++F  RGNV+DL+VG+IIG AF ++V S+V DI+MP +G ++G G DF  + + L
Sbjct: 7   VFNEFKKFIARGNVIDLSVGIIIGGAFNRVVQSIVEDIMMPLVGCVMGNGTDFSNYFLPL 66

Query: 62  RD-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPA 114
                    ++      V  YG F   + +F I+A  +F+ I+ +NKL ++ E     PA
Sbjct: 67  SSEIKSSLISEARKQGAVFAYGSFASVLVNFFILAGVVFVLIQFMNKLVKQTENVKNPPA 126

Query: 115 PTKEEVLLTEIRDLLKEQ 132
              E  LLTEIRDLL++ 
Sbjct: 127 ---EVQLLTEIRDLLQKN 141


>UniRef50_C7MN86 Large conductance mechanosensitive channel protein n=9 Tax=Bacteria
           RepID=C7MN86_CRYCD
          Length = 146

 Score =  121 bits (305), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 55/138 (39%), Positives = 81/138 (58%), Gaps = 9/138 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             +KEF+EF  RGNV+D+AVG+IIGAAF  IV+SLV+D++MP + L IGG DF   AVT 
Sbjct: 3   GFLKEFKEFVSRGNVMDMAVGIIIGAAFTAIVTSLVSDVVMPIVSLAIGGADFSSLAVTF 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                   A  ++YG FIQ + +F++VAF +F  +K I      +   A+A   ++EE  
Sbjct: 63  GTGD---NAATLNYGKFIQAIVNFILVAFVVFCLVKAIAT---TEGHIASAKKDSQEESA 116

Query: 122 LTE---IRDLLKEQNNRS 136
           + E    ++ +     R 
Sbjct: 117 VRECPFCKEEIAASATRC 134


>UniRef50_UPI0001C42BC0 large-conductance mechanosensitive channel n=1 Tax=Bacillus
           pseudofirmus OF4 RepID=UPI0001C42BC0
          Length = 178

 Score =  121 bits (303), Expect = 8e-27,   Method: Composition-based stats.
 Identities = 50/116 (43%), Positives = 76/116 (65%), Gaps = 7/116 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M+I+ EF+EFA+RGNV+D++VGVIIG  F KIV S V D+IMPP  +L G +DF    + 
Sbjct: 1   MNILHEFKEFAVRGNVIDMSVGVIIGTTFAKIVESFVEDVIMPPFSVLFGQVDFSNLYLN 60

Query: 61  LRD------AQGDIPAVVM-HYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP 109
           L D      A+ +   + M  YG+F+ ++  F IVAF +F+ ++ +N++ R  E+P
Sbjct: 61  LSDRRFNSFAEAEAAGIPMLKYGMFLNHIVHFAIVAFILFLFVRQMNRIRRPDEDP 116


>UniRef50_A6W442 Large conductance mechanosensitive channel protein n=2
           Tax=Actinomycetales RepID=A6W442_KINRD
          Length = 151

 Score =  121 bits (303), Expect = 9e-27,   Method: Composition-based stats.
 Identities = 55/141 (39%), Positives = 81/141 (57%), Gaps = 7/141 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV- 59
           M +I+ F++F +RGNV+DLAV V+IGAAF  +V+SLV  +I P +  + G  +     V 
Sbjct: 1   MKLIEGFKDFVLRGNVIDLAVAVVIGAAFTGVVTSLVQGLIDPIIAAVGGSANLDGAWVV 60

Query: 60  ---TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKL--NRKKEEPAAAP 113
              TL +       V +  G  +  V +F+IVA  ++   +  +N+L   RKK E AA  
Sbjct: 61  PLRTLHEGTPQEEVVGIQVGTVVSAVVNFVIVAAVVYFGILTPVNRLLALRKKGEVAAPA 120

Query: 114 APTKEEVLLTEIRDLLKEQNN 134
           AP ++ +LLTEIRDLL  Q  
Sbjct: 121 APAEDVLLLTEIRDLLARQAG 141


>UniRef50_B0K2H2 Large conductance mechanosensitive channel protein n=11
           Tax=Bacteria RepID=B0K2H2_THEPX
          Length = 126

 Score =  121 bits (303), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 56/137 (40%), Positives = 80/137 (58%), Gaps = 18/137 (13%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F+EF MRGNV+DLAV VIIG AF KIV+SLV D++ P +G + G  DF        
Sbjct: 1   MLKGFKEFIMRGNVLDLAVAVIIGGAFNKIVNSLVVDVLTPLIGAIFGAPDFSAIKF--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEE------PAAAPAP 115
                     +  G FI  V +F+++A AI+  +   IN +  +KE+      P A+P P
Sbjct: 58  --------GPISIGNFINAVINFIVIAAAIYFFVVAPINTIKNRKEKQKQQQTPQASPEP 109

Query: 116 TKEEVLLTEIRDLLKEQ 132
           ++E  LL EI D+LKE+
Sbjct: 110 SEEVKLLREILDMLKEK 126


>UniRef50_D0L6D3 Large conductance mechanosensitive channel protein n=8
           Tax=Actinomycetales RepID=D0L6D3_GORB4
          Length = 274

 Score =  120 bits (302), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 6/135 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K FREF ++GNVV+LA  VI+G AF  IV++    I+ P +  +  G D  +    L 
Sbjct: 1   MLKGFREFILKGNVVELATAVIVGTAFTAIVTAFTTGIVEPIINSIPVGTDAAKG---LG 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKLNRKKEEPAAAPAPTKEEVL 121
               D  +  +  G  I    +F+I+A  ++   I   NKL         +     E  L
Sbjct: 58  FQITDKASTYVDIGAVITAFINFIIIAAVVYFLIIMPYNKLAELGGFGKKSE--VTEVAL 115

Query: 122 LTEIRDLLKEQNNRS 136
           LTEIRDLL  + + +
Sbjct: 116 LTEIRDLLDPEGSSA 130


>UniRef50_C5BZI9 Large conductance mechanosensitive channel protein n=1
           Tax=Beutenbergia cavernae DSM 12333 RepID=C5BZI9_BEUC1
          Length = 166

 Score =  120 bits (302), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 44/136 (32%), Positives = 76/136 (55%), Gaps = 6/136 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQ---FAV 59
           ++  F+EF  RGN V+LAVG++IGAAF  +++++V  ++ P +G + G  +      + +
Sbjct: 1   MLSGFKEFIARGNAVELAVGIVIGAAFTAVITAVVEGVLNPLIGGIFGQPNLDNIWVWTL 60

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKE--EPAAAPAPT 116
              D    IP   M  G+ +  + +F++VA AI+  +   +N L R++   +      P 
Sbjct: 61  NEGDPAAGIPPSEMKVGMVLTALVNFVLVAAAIYFLVVAPLNALARRRATGQEPEPAIPA 120

Query: 117 KEEVLLTEIRDLLKEQ 132
           ++  LLTEIRDLL  Q
Sbjct: 121 EDIQLLTEIRDLLARQ 136


>UniRef50_A9WMF7 Large-conductance mechanosensitive channel n=2 Tax=Micrococcineae
           RepID=MSCL_RENSM
          Length = 133

 Score =  120 bits (301), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 8/136 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK FR+F ++GNVVDLAV V+IGAAFG +V++LV +IIMP +  ++G   F        
Sbjct: 1   MIKGFRDFILKGNVVDLAVAVVIGAAFGTVVTTLVNNIIMPLIAGIVGKPSFND---VWA 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK-----LINKLNRKKEEPAAAPAPTK 117
              G  PA  +  G FI  + +F+I+A AI+  +      +I + N K    A    P  
Sbjct: 58  FQIGSDPANKLLLGAFITVLLNFVIIAAAIYFMVVVPMNHVIARRNAKLGIKAGEETPDP 117

Query: 118 EEVLLTEIRDLLKEQN 133
           + VLLTEIRD LK ++
Sbjct: 118 QIVLLTEIRDALKSRS 133


>UniRef50_UPI000050F91C putative large-conductance mechanosensitive channel protein n=1
           Tax=Brevibacterium linens BL2 RepID=UPI000050F91C
          Length = 158

 Score =  119 bits (299), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 6/136 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K FR+F ++GNVV+LA  VIIG AF  IV++    II P +  + G     +      
Sbjct: 1   MLKGFRDFILQGNVVELATAVIIGGAFTAIVTAFSDKIINPLIAAVGGA----EGPALSF 56

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKLNR-KKEEPAAAPAPTKEEV 120
             + ++P   +  G  I    +FLIVA  ++   I  +NKLN  +K        P   E 
Sbjct: 57  QIKENVPETTIDLGAVITAAINFLIVAAIVYFIIIVPMNKLNELRKRGAPEEEVPPTTED 116

Query: 121 LLTEIRDLLKEQNNRS 136
           LL +IR++L+ Q   +
Sbjct: 117 LLGDIREILRTQAATT 132


>UniRef50_A0M1G0 Large-conductance mechanosensitive channel n=10 Tax=Bacteroidetes
           RepID=A0M1G0_GRAFK
          Length = 148

 Score =  119 bits (298), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 55/141 (39%), Positives = 87/141 (61%), Gaps = 7/141 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M I KEF+EFA++GN++D+AVG+IIG AF K+V  LV  IIMPPL +L  GI +      
Sbjct: 1   MGIFKEFKEFAVKGNMIDMAVGIIIGTAFNKVVDVLVKQIIMPPLSMLTDGISYANRKFV 60

Query: 61  LRDAQGD------IPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPA 114
           LRD  G       I  + + YG+ I+ + DF+++ F +F+ +K +N+   K ++P     
Sbjct: 61  LRDGIGAEGDVNYIEEISIGYGLLIETLIDFIVIGFVVFLVVKFMNRFRNKAQDPKNTEV 120

Query: 115 PTKEEV-LLTEIRDLLKEQNN 134
            T +++ LL+ + D ++EQN 
Sbjct: 121 VTPKDIELLSSLNDKMEEQNK 141


>UniRef50_B2GJ27 Large-conductance mechanosensitive channel n=5 Tax=Actinomycetales
           RepID=B2GJ27_KOCRD
          Length = 144

 Score =  119 bits (298), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 11/133 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F+EF M+GNV+DLAV VIIGAAF KIV++LV  ++MP +  ++G  +F  FAV   
Sbjct: 1   MLSGFKEFIMKGNVMDLAVAVIIGAAFSKIVNALVESVLMPAISAVVGSPNFDTFAVVTL 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRKKEEPAAAPAPTK 117
                     + +GV +  V +FL++A A++  I     K+I + NR+      A     
Sbjct: 61  RGNE------LKFGVLLTAVVNFLLIAAAVYFCIVLPMNKMIERRNRRMGIEPTAEPADP 114

Query: 118 EEVLLTEIRDLLK 130
             VLLTEIRD L 
Sbjct: 115 NTVLLTEIRDALA 127


>UniRef50_A4CLF8 Large conductance mechanosensitive channel protein n=1
           Tax=Robiginitalea biformata HTCC2501 RepID=A4CLF8_9FLAO
          Length = 144

 Score =  119 bits (298), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 50/134 (37%), Positives = 79/134 (58%), Gaps = 1/134 (0%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             I+EF+ FA++GN+ D+A+G+IIG AF  +V++LV +I+ PPL      + F      +
Sbjct: 3   GFIREFKNFAIKGNMFDMAIGIIIGTAFNNVVNALVKEILTPPLAFFTSEVQFTNMRWVI 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA-AAPAPTKEEV 120
           R+A      + M YG+ ++ + DF I+A  IF+ IK +N++  + E+PA  A    KE  
Sbjct: 63  REATDTQEEITMGYGILLEALIDFGIIALTIFLLIKALNRIRSRAEDPADKAEVTPKEIE 122

Query: 121 LLTEIRDLLKEQNN 134
           LL  I  L+ EQN 
Sbjct: 123 LLARIEGLMHEQNQ 136


>UniRef50_C8W9F9 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C8W9F9_ATOPD
          Length = 149

 Score =  119 bits (298), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 47/133 (35%), Positives = 74/133 (55%), Gaps = 12/133 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL-IGGIDFKQFAVT 60
             ++EF+EF  +GNV+D+A+G+IIG AF  IV+SLV DII P + L+  GG +    ++ 
Sbjct: 3   KFLEEFKEFIQQGNVMDMAIGIIIGGAFTAIVTSLVNDIINPFIKLISGGGTEVSGLSIP 62

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN------KLNRKKEEPAAAPA 114
           +   Q       + +G FI  + +FLI+AF +F  +K +N      KL + KEE     A
Sbjct: 63  VPGTQNG-----IDFGAFISAIINFLIIAFIVFCMVKALNKFMKASKLEKDKEEAVEEVA 117

Query: 115 PTKEEVLLTEIRD 127
                  L E+++
Sbjct: 118 APHCPHCLEEVKE 130


>UniRef50_Q6MD32 Putative mechanosensitive channel of large conductance n=1
           Tax=Candidatus Protochlamydia amoebophila UWE25
           RepID=Q6MD32_PARUW
          Length = 133

 Score =  118 bits (295), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 54/123 (43%), Positives = 79/123 (64%), Gaps = 2/123 (1%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M+ +KEF+EFA+RGN VDLA+G+IIG  F K V+SLV D+IMP +GLL+GG DF   ++ 
Sbjct: 1   MTWLKEFKEFALRGNRVDLAIGIIIGGVFSKAVNSLVTDVIMPLIGLLLGGADFSALSLK 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
           L   +     V + YG+F+  + D LI++  IF+ IK +N+L  K+    A+      E 
Sbjct: 61  LHLPESAAAPVAVKYGIFVNTLVDLLILSSVIFIVIKGMNRLYEKRS--KASCTRECPEC 118

Query: 121 LLT 123
           L+T
Sbjct: 119 LMT 121


>UniRef50_UPI0000DB7E8B PREDICTED: hypothetical protein, partial n=1 Tax=Apis mellifera
           RepID=UPI0000DB7E8B
          Length = 141

 Score =  117 bits (293), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 55/137 (40%), Positives = 81/137 (59%), Gaps = 15/137 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M  I++F+ F +RGNV+DLAVG+++G AF  +V SLV ++IMPP+GLLIGG+DF    +T
Sbjct: 5   MKFIEQFKAFLLRGNVIDLAVGMVVGTAFTNMVKSLVDNVIMPPIGLLIGGVDFSNLFIT 64

Query: 61  LR------------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
           LR             A     AV ++ G+FI  V   +I+ FAIF+ +K I+KL++    
Sbjct: 65  LRSGSKYPGPYETLGAAQAAGAVTLNIGLFINTVISLVIIGFAIFLVVKGIDKLHK---S 121

Query: 109 PAAAPAPTKEEVLLTEI 125
           PA      +     T+I
Sbjct: 122 PAPKATTKQCPQCCTDI 138


>UniRef50_B8DV17 Large conductance mechanosensitive channel protein n=4
           Tax=Bifidobacterium animalis subsp. lactis
           RepID=B8DV17_BIFA0
          Length = 166

 Score =  117 bits (293), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 43/148 (29%), Positives = 71/148 (47%), Gaps = 17/148 (11%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +I  F++F  RGN+VD+AVGV++GAA   +V+S+V  II P +  + G  D  +      
Sbjct: 1   MIDGFKKFIARGNMVDMAVGVVMGAAVTAVVNSVVDGIINPLVAAIFGKPDLSK-TWNWT 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKLNRKKEE------------P 109
                    V+ +G  +  + +FL++A A++   +  IN L    E+             
Sbjct: 60  ITNWAGENSVISFGSVLNALLNFLLIALAVYFCIVVPINNLRDMTEKAMAKVKGDDSDVA 119

Query: 110 AAAPAPTKEE---VLLTEIRDLLKEQNN 134
           A  P  + EE   +LL +IR+ L  Q  
Sbjct: 120 AEEPDLSPEEQTVILLQDIRNALAAQQP 147


>UniRef50_Q6AGE6 Large-conductance mechanosensitive channel n=7 Tax=Actinomycetales
           RepID=Q6AGE6_LEIXX
          Length = 145

 Score =  116 bits (291), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 47/139 (33%), Positives = 76/139 (54%), Gaps = 12/139 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++ EF+EF +RGNV+DLAV V+IGAAF  IV+++V ++I P +G         +  +   
Sbjct: 1   MLSEFKEFILRGNVIDLAVAVVIGAAFTTIVTAIVTNLINPLIGAFFQANALDETMIV-- 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEE-----PAAAPAPT 116
                +    + +G  +  +  FLI+A  ++ A    +NKL  ++E           AP 
Sbjct: 59  ----SLNGSDIRFGAVLGAIVTFLIIAIVVYFAFVFPLNKLKERQERLRSKGVVEPGAPV 114

Query: 117 KEEVLLTEIRDLLKEQNNR 135
            E  +LTEIRDLLK+Q ++
Sbjct: 115 TELDVLTEIRDLLKKQQSQ 133


>UniRef50_D1BNK2 Large conductance mechanosensitive channel protein n=3
           Tax=Veillonella RepID=D1BNK2_VEIPT
          Length = 155

 Score =  115 bits (288), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 45/130 (34%), Positives = 73/130 (56%), Gaps = 12/130 (9%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
            + +F+ FA +GN++DLA+G+IIGAAF  +V+S+V ++ MP L +  GGIDF    + L 
Sbjct: 4   FLNDFKAFAFKGNMMDLAIGMIIGAAFTALVNSVVNNLFMPVLSVFTGGIDFSNLYLPLS 63

Query: 63  D------------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA 110
                        A       V+ YG FI ++  FLI+AF +F+ ++ + K+ +  +E  
Sbjct: 64  TGSKDAFMAGADIATARAAGSVLPYGTFITDLIQFLILAFVVFLMVRGLAKMMKSAKEEE 123

Query: 111 AAPAPTKEEV 120
            A AP  +E 
Sbjct: 124 VAEAPATKEC 133


>UniRef50_Q2N8W2 Mechanosensitive channel n=1 Tax=Erythrobacter litoralis HTCC2594
           RepID=Q2N8W2_ERYLH
          Length = 169

 Score =  114 bits (287), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 54/146 (36%), Positives = 84/146 (57%), Gaps = 15/146 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS+  EF++F  RGNVVDLAVGV+IGAAF  IV+ L   I+MP +G + G IDF  + + 
Sbjct: 1   MSLGTEFKKFIARGNVVDLAVGVVIGAAFSGIVTQLTEAILMPLIGWIFGDIDFSNWFLR 60

Query: 61  LRDAQG-------------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK-K 106
           L +                +    ++ YG  I  + +FLIVAFA+FM ++ +NK++ + K
Sbjct: 61  LGEIPEGYEGALDNYEQLKEAGVAMIGYGALITALINFLIVAFALFMLVRSVNKVSDEIK 120

Query: 107 EEPAAAPAPTKEEVLLTEIR-DLLKE 131
              A     +K + + T+ + D+LK+
Sbjct: 121 ARQAETEDSSKSDDVPTDPQLDVLKK 146


>UniRef50_D1BCH3 Large conductance mechanosensitive channel protein n=1
           Tax=Sanguibacter keddieii DSM 10542 RepID=D1BCH3_SANKS
          Length = 164

 Score =  114 bits (286), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 48/136 (35%), Positives = 74/136 (54%), Gaps = 9/136 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           +++  F+EF MRGN +DLAVGVIIGAAF  +V+++V ++  P +  + G  D        
Sbjct: 3   NVLNGFKEFIMRGNAIDLAVGVIIGAAFSAVVAAIVENLFTPLIAAIFGEPDLSSV---- 58

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLN--RKKEEPAAAPAPTKE 118
                 I       G  +  V +FL VA A++  + L +N L+  RKK        P+++
Sbjct: 59  --LSFTINGAAFSIGAVLNAVINFLFVAIALYFFVVLPLNHLSKLRKKGIIEEPEGPSED 116

Query: 119 EVLLTEIRDLLKEQNN 134
            ++LT+IRDLL  QN 
Sbjct: 117 VLILTQIRDLLLVQNG 132


>UniRef50_C8WNX6 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C8WNX6_EGGLE
          Length = 153

 Score =  114 bits (286), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 5/119 (4%)

Query: 11  AMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPA 70
             +GNV+DLAV V+IG AF  IV+S+V+D+IMP + L+ GGIDF    + L        A
Sbjct: 12  INQGNVMDLAVAVVIGTAFTAIVNSVVSDLIMPLISLVTGGIDFSDMKIPLGTG---PDA 68

Query: 71  VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR--KKEEPAAAPAPTKEEVLLTEIRD 127
               YG FI  V  FLI+A  +F+ +K +++     ++ +        K    L E+ +
Sbjct: 69  AAFTYGNFINAVIQFLIIALVVFLIVKALSRARMLTRRGKHIEEQDAPKCPFCLEEVNE 127


>UniRef50_A6M387 Large-conductance mechanosensitive channel n=7 Tax=cellular
           organisms RepID=MSCL_CLOB8
          Length = 146

 Score =  114 bits (285), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 64/131 (48%), Positives = 84/131 (64%), Gaps = 8/131 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + KEF+EFAM+GN+V LA+GV+IG AF KIV+SLV DIIMP +GLL+G +DF     TL 
Sbjct: 1   MFKEFKEFAMKGNMVSLAIGVVIGGAFSKIVTSLVNDIIMPLVGLLMGRVDFSNLFFTLG 60

Query: 63  DAQG-------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
                      D     ++YG+FI N+ DFLIVAF+IF+ I+ I+KL +KK E    P  
Sbjct: 61  SGNFKTVQEAKDAGVATVNYGIFINNIIDFLIVAFSIFIIIQQISKLTKKKGE-NIVPDK 119

Query: 116 TKEEVLLTEIR 126
            K +   TEI 
Sbjct: 120 KKCKYCYTEIN 130


>UniRef50_B9CMP0 Large conductance mechanosensitive channel protein n=1
           Tax=Atopobium rimae ATCC 49626 RepID=B9CMP0_9ACTN
          Length = 142

 Score =  114 bits (285), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 43/121 (35%), Positives = 69/121 (57%), Gaps = 6/121 (4%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL-IGGIDFKQFAVT 60
            +  EF++F  RGNV+D+A+GVIIG AF  IV+SLV DI+ P + L+  GG +    ++ 
Sbjct: 3   KLFAEFKDFIARGNVMDMAIGVIIGGAFMAIVNSLVNDIVNPFIKLISGGGTEVSGLSIP 62

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
           +   +       + +G FI  + +FLI+A  +F+ +K INK  + K+E   +P       
Sbjct: 63  VAGTEHG-----IDFGSFISAIINFLIIAVIVFLLVKAINKFMKGKKESTDSPTQVCPHC 117

Query: 121 L 121
           L
Sbjct: 118 L 118


>UniRef50_B5GFS7 Mechanosensitive channel n=12 Tax=Streptomyces RepID=B5GFS7_9ACTO
          Length = 194

 Score =  113 bits (284), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 42/142 (29%), Positives = 68/142 (47%), Gaps = 13/142 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            + + F+ F MRGNV+DLAV V+IGAAF  IV+++V  +I P +G   G  D  Q++  L
Sbjct: 8   GVWEGFKSFLMRGNVIDLAVAVVIGAAFTNIVNAVVKGVINPVVGA-FGTQDLDQYSYCL 66

Query: 62  ------RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-----INKLNRKKEEP- 109
                      +   + + +G  +     FLI A  ++  + L     + +L  ++E   
Sbjct: 67  ESPCVPAHGGEEAQGIQIMWGTVLSAALTFLITAAVVYFLMVLPMSRYLARLAARREAKY 126

Query: 110 AAAPAPTKEEVLLTEIRDLLKE 131
                P  E  +L +IRD L  
Sbjct: 127 GTPEVPVSELDVLKDIRDELVA 148


>UniRef50_Q7UW50 Probable large-conductance mechanosensitive channel n=1
           Tax=Rhodopirellula baltica RepID=Q7UW50_RHOBA
          Length = 168

 Score =  113 bits (284), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 60/154 (38%), Positives = 92/154 (59%), Gaps = 22/154 (14%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI--GGIDFKQFA 58
           M +++EF+EFA++G+V+DLAVGV+IG AF  IV SLV +IIMPP+ LL    G++FK+ A
Sbjct: 15  MGLVQEFKEFALKGSVIDLAVGVVIGGAFSGIVKSLVDNIIMPPINLLTARSGVNFKEAA 74

Query: 59  VTLRDAQGDIPAV-----------------VMHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
           +T+      +                    +++YG F Q +F+FL++A A+F+AIKLIN 
Sbjct: 75  LTIETESPKLDDAGKIIEGEGAEMLVQDYPILNYGPFTQTIFEFLLIALALFVAIKLINA 134

Query: 102 LNRKK---EEPAAAPAPTKEEVLLTEIRDLLKEQ 132
              +     E      P+++  LL EIRD L++ 
Sbjct: 135 ARSRMEDEPEEEEVAKPSEDIQLLREIRDALQKS 168


>UniRef50_Q9RRR4 Large conductance mechanosensitive channel n=1 Tax=Deinococcus
           radiodurans RepID=Q9RRR4_DEIRA
          Length = 128

 Score =  113 bits (284), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 44/133 (33%), Positives = 69/133 (51%), Gaps = 10/133 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  FR+F +RGNVVDLAVGV+IGAAF  +V++     + P + L  GG           
Sbjct: 1   MLNGFRDFILRGNVVDLAVGVVIGAAFNNVVAAFTKAFLDPLIRLATGG-------HGKV 53

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAI-FMAIKLINKLNR--KKEEPAAAPAPTKEE 119
                +  +   +G F+  + +FL+ A  + F  +  +N      K+ E AA   P+ EE
Sbjct: 54  AGTFAVNGITFDWGTFVSTLINFLLTAAVLYFFVVMPMNAATERLKRSEKAAEAEPSNEE 113

Query: 120 VLLTEIRDLLKEQ 132
            LL EIRD ++ +
Sbjct: 114 KLLAEIRDAVRSR 126


>UniRef50_A3CM47 Large conductance mechano-sensitive ion channel, putative n=44
           Tax=Streptococcus RepID=A3CM47_STRSV
          Length = 127

 Score =  113 bits (283), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 51/135 (37%), Positives = 77/135 (57%), Gaps = 12/135 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP-LGLLIGGIDFKQFAVTL 61
           ++K+ +EF +RGNV+DLAVGVII  AFG IV+SL+ D+I P  L  ++   + +Q +   
Sbjct: 1   MLKDLKEFLLRGNVIDLAVGVIIANAFGAIVTSLITDVITPLFLNPILKAANLEQISQLK 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK---LNRKKEEPAAAPAPTKE 118
            +         + YG F+  V +FL++   +F  +K   K   L +KKEE   APA   E
Sbjct: 61  WNG--------IAYGNFLSAVINFLVIGTVLFFIVKSAEKAQSLAKKKEEVEEAPAGPTE 112

Query: 119 EVLLTEIRDLLKEQN 133
             +L EI+ LL E+ 
Sbjct: 113 LEVLQEIKALLAEKK 127


>UniRef50_B4D701 Large conductance mechanosensitive channel protein n=2
           Tax=Verrucomicrobia RepID=B4D701_9BACT
          Length = 141

 Score =  113 bits (283), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 14/131 (10%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           EF+ F M+GNV+DLAVG++IGAAFG +V      II P +G   GG D            
Sbjct: 9   EFKTFIMKGNVIDLAVGLLIGAAFGAVVKDFTDGIINPLIGYFGGGKDVS---------- 58

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMA-IKLINKLNRKKEEPAA-APAPTKEEVLLT 123
             +   +   G+ I  +  FLI A  +F   +K +NKL    E+  A AP P ++  LL 
Sbjct: 59  --LHLWIFDVGLVINAIIKFLITAVVLFFIFVKPMNKLKAMSEKKEAGAPPPPEDIQLLR 116

Query: 124 EIRDLLKEQNN 134
           EIRDLLK    
Sbjct: 117 EIRDLLKAGAK 127


>UniRef50_D2R1B6 Large conductance mechanosensitive channel protein n=1
           Tax=Pirellula staleyi DSM 6068 RepID=D2R1B6_9PLAN
          Length = 166

 Score =  113 bits (283), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 68/166 (40%), Positives = 90/166 (54%), Gaps = 34/166 (20%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-GGIDFKQFAV 59
           M ++KEFR+FA+RGNV+DLAVGVIIG AFGKI SSLV D++MP LGL+    +DFK   +
Sbjct: 1   MGLLKEFRDFALRGNVIDLAVGVIIGGAFGKITSSLVGDVMMPALGLVANNALDFKSRYI 60

Query: 60  TLRDAQGDIPAV--------------------------VMHYGVFIQNVFDFLIVAFAIF 93
            L  A+    A                           V+ YG F+  V DF I+AF +F
Sbjct: 61  RLFSAEQLAAATKTTTEEANKLIDSGVPFSIVSENKLPVIAYGSFLTTVIDFAILAFCVF 120

Query: 94  MAIKLINKLNRKKEE-------PAAAPAPTKEEVLLTEIRDLLKEQ 132
           M +K++N   ++ E         A    P  +E LL EIRDLLK +
Sbjct: 121 MVVKIMNTAIKRLEALRKAEVAAAPPAEPPAQEKLLMEIRDLLKAK 166


>UniRef50_A9HW97 Large-conductance mechanosensitive channel n=98 Tax=Proteobacteria
           RepID=MSCL_BORPD
          Length = 148

 Score =  113 bits (282), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 62/143 (43%), Positives = 91/143 (63%), Gaps = 13/143 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAVT 60
             +KEFR+FA++GN +DLAVGVIIGAAFGKIV S+V D+IMP +  ++GG +DF    + 
Sbjct: 6   GFLKEFRDFAVKGNAIDLAVGVIIGAAFGKIVDSVVKDLIMPLVNYILGGSVDFSNKFLV 65

Query: 61  LRDAQG-----------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK-KEE 108
           L    G              A+V+ +G F+  + +F+++A  +F+ +K IN   RK +E 
Sbjct: 66  LSAPDGYAGPMTYADLTKAGAIVLAWGNFLTILINFILLALVVFIIVKAINAARRKEEEA 125

Query: 109 PAAAPAPTKEEVLLTEIRDLLKE 131
           PA   AP ++ V+L EIRDLLK+
Sbjct: 126 PAEPAAPPEDVVVLREIRDLLKK 148


>UniRef50_C4FGI6 Putative uncharacterized protein n=1 Tax=Bifidobacterium angulatum
           DSM 20098 RepID=C4FGI6_9BIFI
          Length = 179

 Score =  112 bits (280), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 44/133 (33%), Positives = 71/133 (53%), Gaps = 11/133 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           IK F++F  RG+++D+AVGV++G+A   +V+S+V  +I P +G++ G  D          
Sbjct: 44  IKGFKKFISRGSMIDMAVGVVMGSAVTTVVNSIVNHLISPLIGMIGGVPDMSGV------ 97

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRK-KEEPAAAPAPTKEE-- 119
                    + +G  +  + +FL++  A+++ I L INKL      E A    PT EE  
Sbjct: 98  LTITFNGATISFGAILNAIINFLLIGVAVYLCIVLPINKLRDMGANEEAENTEPTTEEQT 157

Query: 120 -VLLTEIRDLLKE 131
             +L EIRD LK 
Sbjct: 158 LAVLQEIRDELKR 170


>UniRef50_B4V9Z0 Mechanosensitive channel n=3 Tax=Streptomyces RepID=B4V9Z0_9ACTO
          Length = 172

 Score =  111 bits (279), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 47/143 (32%), Positives = 69/143 (48%), Gaps = 13/143 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S++  F+ F MRGNV+DLAV V+IGAAF  IV+S+V  II P +G + G      ++  L
Sbjct: 7   SVLAGFKAFLMRGNVIDLAVAVVIGAAFTNIVNSVVKGIIGPLVGAV-GTKSLDGYSSCL 65

Query: 62  RD-----AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK-------LNRKKEEP 109
           +      A+G+   V + +G  +     F+I A  ++  + L            RK  E 
Sbjct: 66  KGPCGVTAKGEPTGVNILWGSVLNATLTFVITAAVVYFLMVLPMAKYLARQEQRRKAREG 125

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQ 132
                   E  +L EIRD L  Q
Sbjct: 126 VQETMEITELEVLKEIRDTLVAQ 148


>UniRef50_A9KIC1 Large conductance mechanosensitive channel protein n=2
           Tax=Clostridiales RepID=A9KIC1_CLOPH
          Length = 147

 Score =  111 bits (278), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 45/128 (35%), Positives = 76/128 (59%), Gaps = 11/128 (8%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             +KEFREFA++GNV++LAVGVIIG+AF  IV+SL  +I+ P +GL     +F    +  
Sbjct: 3   KFLKEFREFALKGNVMNLAVGVIIGSAFQGIVTSLTDNILSPIIGLFTRQ-NFDSLQL-- 59

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL---NRKKEEPAAAPAPTKE 118
                +I  + + YG FI  + +F+I+AF +F+ +K +N++   + K+++    P     
Sbjct: 60  -----NIFGITLRYGAFITALINFVIMAFVVFLLVKGMNRILSFDDKRKKVEVKPTEKDC 114

Query: 119 EVLLTEIR 126
              +T+I 
Sbjct: 115 PYCMTKIN 122


>UniRef50_A7X204 Large-conductance mechanosensitive channel n=51 Tax=Staphylococcus
           aureus RepID=MSCL_STAA1
          Length = 120

 Score =  111 bits (278), Expect = 8e-24,   Method: Composition-based stats.
 Identities = 61/131 (46%), Positives = 91/131 (69%), Gaps = 11/131 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNV+DLA+ V++GAAF KI+SSLV +IIMP +G + G +DF +      
Sbjct: 1   MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAK------ 54

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               +     + YG+FIQ+V DF+I+AFA+F+ +K+ N L +K+E    A    +  VLL
Sbjct: 55  ----EWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAEEEA-VVEENVVLL 109

Query: 123 TEIRDLLKEQN 133
           TEIRDLL+E+ 
Sbjct: 110 TEIRDLLREKK 120


>UniRef50_B3DRI7 Large-conductance mechanosensitive channel n=17
           Tax=Actinobacteridae RepID=B3DRI7_BIFLD
          Length = 168

 Score =  111 bits (278), Expect = 8e-24,   Method: Composition-based stats.
 Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 14/141 (9%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  F++F  RG+++D+AVGV++G+A   +V+S+V ++I P +G++ G  D          
Sbjct: 33  LNGFKKFLSRGSMIDMAVGVVMGSAVTAVVNSIVDNLISPLIGMIGGVPDLSGL------ 86

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNR----KKEEPAAAPAPTKE 118
                    + +G  +  + +FL+V  A++  + L INKL      + E  A    P+ E
Sbjct: 87  LTITFNNSTVSFGAILNALINFLLVGVAVYFCVILPINKLRDLTAIQDEADAEEQGPSVE 146

Query: 119 E---VLLTEIRDLLKEQNNRS 136
           E     L EIRD LK+ N+ +
Sbjct: 147 EQTLATLQEIRDELKKANDSA 167


>UniRef50_A8LHK6 Large conductance mechanosensitive channel protein n=5
           Tax=Actinomycetales RepID=A8LHK6_FRASN
          Length = 169

 Score =  111 bits (277), Expect = 9e-24,   Method: Composition-based stats.
 Identities = 50/130 (38%), Positives = 74/130 (56%), Gaps = 13/130 (10%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           ++ F++F MRGN+VDLA+ V++G AF  +V SLV +I  P +  + G  DF     T+ D
Sbjct: 26  LRGFKQFLMRGNIVDLAIAVVVGTAFTAVVQSLVKNIFTPLIAAIGGEPDFSSLTFTIND 85

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL----INKLNRK--KEEPAAAPAPTK 117
           ++         YG FI +V  F++VA  I+  I L     N++ R+  + EP   PA + 
Sbjct: 86  SK-------FRYGAFINDVIAFIVVAAVIYFVIVLPLAKANEMRRRGEEPEPQEEPAISD 138

Query: 118 EEVLLTEIRD 127
           E  LLTEIRD
Sbjct: 139 EAKLLTEIRD 148


>UniRef50_C7MC43 Large conductance mechanosensitive channel protein n=1
           Tax=Brachybacterium faecium DSM 4810 RepID=C7MC43_BRAFD
          Length = 151

 Score =  111 bits (277), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 43/137 (31%), Positives = 73/137 (53%), Gaps = 10/137 (7%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K F++F M+GNV+DLAVGV+IG+AF  ++++ V ++I P +  + GG +    +  +  
Sbjct: 1   MKGFKDFVMQGNVIDLAVGVVIGSAFTALITAFVENLIQPVIN-VFGGSNVDGLSFKIIQ 59

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMA----IKLINKLNRKKE--EPAAAPAPTK 117
           A     A  +  G  +  +  FLI A  ++      I    +L+RK+         + ++
Sbjct: 60  AN---EATRIDVGGVLSAIIAFLITAAVVYFVFVLPISAARRLDRKRRGLPEEEETSVSE 116

Query: 118 EEVLLTEIRDLLKEQNN 134
           + VLLTEIRD L  Q  
Sbjct: 117 DIVLLTEIRDALTVQQG 133


>UniRef50_A0JZ24 Large conductance mechanosensitive channel protein n=1
           Tax=Arthrobacter sp. FB24 RepID=A0JZ24_ARTS2
          Length = 130

 Score =  111 bits (277), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 19/141 (13%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  F+ F M+GNVVDLAV V++GAAF  +V+S+V  ++ P +G L      +        
Sbjct: 1   MTGFKNFIMKGNVVDLAVAVVMGAAFSAVVTSIVEGLLTPLIGRLFNAKGIEDMQWEG-- 58

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKK-------EEPAAAPAP 115
                      YG  I +V  FL+V  +I+  + L +N +  ++        E     A 
Sbjct: 59  ---------FMYGSVISSVISFLLVGASIYFVVVLPMNHMIERRNRRLGIGTEVKEEAAE 109

Query: 116 TKEEVLLTEIRDLLKEQNNRS 136
             +  LLTEIRD L+  + R+
Sbjct: 110 DPQIALLTEIRDSLRSGSTRA 130


>UniRef50_A7B9R5 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7B9R5_9ACTO
          Length = 137

 Score =  110 bits (276), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 56/143 (39%), Positives = 79/143 (55%), Gaps = 15/143 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +I+ F+EF  RGNVV+LAVGVIIGAAF  IV +LV  II P +  +IG  DF    +   
Sbjct: 1   MIQGFKEFISRGNVVELAVGVIIGAAFKNIVDALVDGIINPLIAAVIGKPDFSDAFILT- 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKLNRKKEEPAAA--------P 113
                +    + +GV I  V +FL++A A+++  I  +N LN + ++ AAA         
Sbjct: 60  -----LNGTDVKFGVLITAVINFLLMAIALYLCIIVPMNALNERMKKQAAADEAEAKANK 114

Query: 114 APTKEEVLLTEIRDLLKEQNNRS 136
             + E  LLTEIRD L +   R 
Sbjct: 115 EESDEVKLLTEIRDALAQGTPRH 137


>UniRef50_Q82ZB4 Large-conductance mechanosensitive channel n=40 Tax=Lactobacillales
           RepID=MSCL_ENTFA
          Length = 149

 Score =  110 bits (276), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 3/137 (2%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFA-VTL 61
           +IKEF+EF MRG+V+DLAVGV+IG+AF  IV+ +V  +I P + L+      K+ A   L
Sbjct: 1   MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDAL 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK--KEEPAAAPAPTKEE 119
                 +  V  + G  I  +  FLI AF +F+ +K  NK+  +  KEE A        E
Sbjct: 61  GALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSE 120

Query: 120 VLLTEIRDLLKEQNNRS 136
             L EIRDLL  Q   +
Sbjct: 121 DYLKEIRDLLAAQTPPA 137


>UniRef50_B8ZU13 Large-conductance mechanosensitive channel n=23 Tax=Mycobacterium
           RepID=MSCL_MYCLB
          Length = 154

 Score =  110 bits (275), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 41/134 (30%), Positives = 67/134 (50%), Gaps = 6/134 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + + F+EF  RGN+VDLAV V+IG AF  +++     II P +  +  G++ +     LR
Sbjct: 1   MFRGFKEFLSRGNIVDLAVAVVIGTAFTALITKFTDSIITPLINRV--GVNQQTNISPLR 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT--KEEV 120
              G   A+ ++  + +    +FL++A  ++  + L     RK  E           + V
Sbjct: 59  IDIGGDQAIDLN--IVLSAAINFLLIALVVYFLVVLPYTTIRKHGEVEQFDTDLIGNQVV 116

Query: 121 LLTEIRDLLKEQNN 134
           LL EIRDLL + N 
Sbjct: 117 LLAEIRDLLAQSNG 130


>UniRef50_D0WJR5 Large conductance mechanosensitive channel protein n=1
           Tax=Actinomyces sp. oral taxon 848 str. F0332
           RepID=D0WJR5_9ACTO
          Length = 172

 Score =  110 bits (275), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 46/133 (34%), Positives = 74/133 (55%), Gaps = 11/133 (8%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           ++I+ F++F MRGNV++LAV V+I  AF  IV++LV  +I P +G L G  +F       
Sbjct: 23  TMIEGFKKFIMRGNVIELAVAVVIADAFSPIVNNLVGKVINPTIGGLFGKPNFNNI---- 78

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLN----RKKEEPAAAPAPT 116
              +  +    +  G  +  +  FL++A A+++A+   +NKLN    ++K   A     +
Sbjct: 79  --GEFHVGDATVQPGTVLTALIAFLLIAAAVYLALVFPMNKLNERMAKRKGLNAEEAEVS 136

Query: 117 KEEVLLTEIRDLL 129
            E  LLTEIRD L
Sbjct: 137 DEVRLLTEIRDAL 149


>UniRef50_Q31LP8 Large-conductance mechanosensitive channel n=2 Tax=Synechococcus
           elongatus RepID=MSCL_SYNE7
          Length = 133

 Score =  109 bits (274), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 51/135 (37%), Positives = 78/135 (57%), Gaps = 13/135 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           +  I++F+ F ++GNVV+LAV VIIG AF KIVSS V D++MP +  LI G D++   + 
Sbjct: 9   VGFIRDFQAFILKGNVVELAVAVIIGGAFNKIVSSFVGDLVMPLVNPLIPGGDWRTAVI- 67

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
                       +  G F  +V DFLI+AF +++AI+ I +  RK+E   AA  P  ++ 
Sbjct: 68  ---------GPGLKIGSFAGSVIDFLIIAFVLYLAIRAIERFKRKEEAVVAAAEPDVQQQ 118

Query: 121 LLT---EIRDLLKEQ 132
           +L     I D L+ +
Sbjct: 119 MLATLERIADNLEAR 133


>UniRef50_D2B464 Large conductance mechanosensitive channel protein n=6
           Tax=Actinomycetales RepID=D2B464_STRRD
          Length = 134

 Score =  109 bits (274), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 42/129 (32%), Positives = 66/129 (51%), Gaps = 14/129 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F++F MRGNVV+LA+ V+IGAAF  IV+S V D++ P +  + G  DF    +   
Sbjct: 1   MLSGFKKFLMRGNVVELAIAVVIGAAFTAIVNSFVKDVLTPLIAAIGGQPDFSGLTLR-- 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
                I A  + YG+F+  +  FL+VA  I+  +        +  E  +A    +EE   
Sbjct: 59  -----IGAGEIRYGLFLNALIAFLMVAAVIYFLVV-------RPYERISARFAAREEATH 106

Query: 123 TEIRDLLKE 131
            E  + L E
Sbjct: 107 RECPECLSE 115


>UniRef50_B0S3E4 Large-conductive mechanosensitive channel n=2 Tax=Finegoldia magna
           RepID=B0S3E4_FINM2
          Length = 133

 Score =  109 bits (273), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 45/124 (36%), Positives = 71/124 (57%), Gaps = 8/124 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F   GNV+DLAV VI+GAA  ++V  L+  +I P +G    G++ K+ AVTL 
Sbjct: 1   MLKEFKKFITEGNVMDLAVAVIMGAAVKEMVDGLINGLIAPLIGAATAGVNMKELAVTL- 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK-KEEPAAAPAPTKEEVL 121
                   V + YG+F+  +  F+I+AF +F+ +K +NK      +EPA  P        
Sbjct: 60  ------AGVKLQYGLFLDALVKFIIIAFVVFIMVKAVNKGRDALHKEPAPEPTTKTCPYC 113

Query: 122 LTEI 125
            +EI
Sbjct: 114 KSEI 117


>UniRef50_Q04FK1 Large-conductance mechanosensitive channel n=4 Tax=Leuconostocaceae
           RepID=MSCL_OENOB
          Length = 129

 Score =  109 bits (273), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 55/134 (41%), Positives = 80/134 (59%), Gaps = 8/134 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++ EF++F MRGN +DLAVGV++GAAF  IV S+V ++I P +G+  G +D      ++ 
Sbjct: 1   MLNEFKQFIMRGNAIDLAVGVVMGAAFTSIVKSIVTNLIGPIIGIFAGAVDLSSLKFSIG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
            A       V  YG  +  V +F+IV F IF+ IK INK  +K E+   A A + E  LL
Sbjct: 61  PA-------VFKYGAVLNQVINFIIVGFIIFLIIKAINKFFKKNEKKEDAEAES-EVKLL 112

Query: 123 TEIRDLLKEQNNRS 136
           T+IR  LK+ N  +
Sbjct: 113 TDIRAELKKSNQST 126


>UniRef50_D2MPY5 Large conductance mechanosensitive channel protein n=1
           Tax=Bulleidia extructa W1219 RepID=D2MPY5_9FIRM
          Length = 125

 Score =  108 bits (271), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 49/131 (37%), Positives = 82/131 (62%), Gaps = 8/131 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + + EF+EFA++GNV+DLAVGVIIG AF  I+ SL+ +II P +G+L    DF Q  + +
Sbjct: 3   NFMNEFKEFALKGNVMDLAVGVIIGGAFQAIIKSLIDNIINPIIGILF-QADFSQVVIRM 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                   +V +  G F+  + +F+++AF +F+ +K IN+L +  +E  + P  ++E  L
Sbjct: 62  -------GSVNLGVGAFVSTIINFVLLAFVLFLMVKAINQLKKLNQEEESTPEKSEEAQL 114

Query: 122 LTEIRDLLKEQ 132
           L +I + LK+ 
Sbjct: 115 LEKILEQLKKN 125


>UniRef50_C5RAB3 MscL family large conductance mechanosensitive ion channel n=1
           Tax=Weissella paramesenteroides ATCC 33313
           RepID=C5RAB3_WEIPA
          Length = 130

 Score =  108 bits (271), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 53/135 (39%), Positives = 76/135 (56%), Gaps = 9/135 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + I EF++F MRGNV+DLAV  I+GAAF  +V S+V D+IMP +G++ G I F      +
Sbjct: 3   NFINEFKDFIMRGNVMDLAVAFIMGAAFQTVVKSVVDDLIMPLIGIITGSISFSSIVWHV 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR--KKEEPAAAPAPTKEE 119
             A        +  G FI  +  FL+ +FA+F+ +K I K     KK+      AP  E 
Sbjct: 63  GSAD-------IKVGSFIGTLITFLLTSFAVFLILKAIRKAQSMTKKQAEEEEIAPETEL 115

Query: 120 VLLTEIRDLLKEQNN 134
           V+L EIRD L  + +
Sbjct: 116 VVLQEIRDALAAKKD 130


>UniRef50_B0T274 Large-conductance mechanosensitive channel n=42 Tax=Bacteria
           RepID=MSCL_CAUSK
          Length = 161

 Score =  108 bits (270), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 71/137 (51%), Positives = 85/137 (62%), Gaps = 6/137 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSI+KEFREF  RGNVVDLAVGVIIGAAF  IV SLV  +IMPP+GL+ GG+DF +    
Sbjct: 1   MSIVKEFREFIARGNVVDLAVGVIIGAAFNGIVKSLVDGVIMPPIGLVTGGLDFSKLQWV 60

Query: 61  LRDAQGDIPA---VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTK 117
           L+       A   V + YG FI  V  FLIVA  +F+ +KL+N + R      A  AP  
Sbjct: 61  LKPEDPVTEAVELVAIQYGAFINTVIQFLIVAVVVFLLVKLVNHIRRADAAEPAPEAPAA 120

Query: 118 EEV---LLTEIRDLLKE 131
                 LLTEIRDLL +
Sbjct: 121 PTPEERLLTEIRDLLAK 137


>UniRef50_C0QYW6 Large-conductance mechanosensitive channel n=2 Tax=Brachyspira
           RepID=MSCL_BRAHW
          Length = 155

 Score =  107 bits (269), Expect = 7e-23,   Method: Composition-based stats.
 Identities = 48/113 (42%), Positives = 76/113 (67%), Gaps = 12/113 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IKEF++F M+G+++D+AVG++IGAAF KIV+S V DI+MPP+G+++ GIDF    + ++
Sbjct: 1   MIKEFKKFIMKGSILDMAVGLVIGAAFTKIVNSFVDDILMPPIGMILSGIDFSNIFIVIK 60

Query: 63  ------------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN 103
                       +A  +  AVV+  GVFI  +  F+I A ++F+ IKL NK+ 
Sbjct: 61  KGTDTLGNYNSIEAARNAGAVVIGIGVFINAIISFIITALSLFIIIKLFNKIQ 113


>UniRef50_Q82H65 Putative mechanosensitive channel n=2 Tax=Streptomyces
           RepID=Q82H65_STRAW
          Length = 158

 Score =  107 bits (269), Expect = 7e-23,   Method: Composition-based stats.
 Identities = 44/146 (30%), Positives = 66/146 (45%), Gaps = 14/146 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            ++  F+ F MRGNVVDLAV V+IGAAF  IV+S+V  II P +G   G  D  +++   
Sbjct: 8   GVLAGFKAFLMRGNVVDLAVAVVIGAAFTNIVNSVVKGIINPLVGA-FGTKDLDKYSSCF 66

Query: 62  RDA------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-------NKLNRKKEE 108
           R              + + +G  + +   F+I A  ++  + L         +  RK + 
Sbjct: 67  RAPCQVAKDGTVTKGIPIMWGTVLSSTLSFVITAAVVYFLMVLPMSKYLARMEARRKAKA 126

Query: 109 PAAAPAPTKEEVLLTEIRDLLKEQNN 134
                    E  +L EIRD L  Q  
Sbjct: 127 GMQEVIEVTELQVLKEIRDALVAQRG 152


>UniRef50_C7HUU0 Large conductance mechanosensitive channel protein n=2
           Tax=Anaerococcus RepID=C7HUU0_9FIRM
          Length = 135

 Score =  106 bits (265), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 43/112 (38%), Positives = 67/112 (59%), Gaps = 9/112 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + KEF+EF  +GNVVDLA+G+I+G+AF  IV+++V  I+MP +  L  G+D++  AV   
Sbjct: 1   MWKEFKEFISKGNVVDLAIGLIMGSAFTAIVTAVVDGILMPIISGLTAGVDYEDLAVNFF 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPA 114
            A+       +  G  I  +  FLI++  +F+ +K +NK   KKEE   A  
Sbjct: 61  GAK-------LQIGSVINAIITFLIISLFLFLIVKALNKA--KKEEVVEATT 103


>UniRef50_B5Y8I7 Large conductance mechanosensitive channel protein n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y8I7_COPPD
          Length = 127

 Score =  106 bits (265), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 47/138 (34%), Positives = 67/138 (48%), Gaps = 19/138 (13%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F+ F  RGNV+DLA+ VIIGAAF  +V SLV DI  P LG+L G  DF  + V   
Sbjct: 1   MLKGFKAFLSRGNVLDLAIAVIIGAAFNSVVKSLVEDIFTPLLGMLGGLPDFSSWKV--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-----NKLNRKKEEP---AAAPA 114
                     +  G F+ ++  FL  A  I+  +        N    K+       A   
Sbjct: 58  --------GPLMLGSFVNSLLSFLFTAAVIYFVLVAPAEALKNAAKEKQRAETLDKATET 109

Query: 115 PTKEEVLLTEIRDLLKEQ 132
           P +E  LL  I +LL+++
Sbjct: 110 PPEEIQLLRRIVELLEKK 127


>UniRef50_A7VB12 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
           RepID=A7VB12_9CLOT
          Length = 141

 Score =  106 bits (265), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 42/117 (35%), Positives = 66/117 (56%), Gaps = 8/117 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
              +EF+EFA++GNV+D+A+GVIIG AF  +V+SL    I P +G + G          +
Sbjct: 3   KFFQEFKEFALKGNVLDMAIGVIIGGAFSGLVTSLTDCFINPIIGCIGGA--------EV 54

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE 118
           +     +    + YG FI  V +F+I+AF IF+ +K I KL    ++  AA   T++
Sbjct: 55  QGKIHLLGDQYIDYGSFITAVINFIIMAFIIFLLMKGIKKLLSLGKKEEAAAPLTRK 111


>UniRef50_A4AI90 Large-conductance mechanosensitive channel n=1 Tax=marine
           actinobacterium PHSC20C1 RepID=A4AI90_9ACTN
          Length = 137

 Score =  106 bits (264), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 48/138 (34%), Positives = 71/138 (51%), Gaps = 6/138 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F+ F +RGNV+DLAV V+IGAAF  +V+++V  +  P +G L              
Sbjct: 1   MLSGFKTFILRGNVIDLAVAVVIGAAFTAVVNTIVEAVFNPLIGALFNAETLSTALPVTI 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL----INKLNRKKEEPAAAP-APTK 117
              G   AV +++G  I  +  FL+VA  ++ AI       NKL   ++     P A   
Sbjct: 61  PTAGGEDAV-IYFGAVIAALVQFLLVAVVVYFAIVAPMNYANKLAAARKPVVIEPEAGPT 119

Query: 118 EEVLLTEIRDLLKEQNNR 135
           E  LL +IRDLL +QNN 
Sbjct: 120 EAELLLQIRDLLAKQNNS 137


>UniRef50_D1AZE9 Large conductance mechanosensitive channel protein n=1
           Tax=Sulfurospirillum deleyianum DSM 6946
           RepID=D1AZE9_SULD5
          Length = 142

 Score =  105 bits (263), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 48/125 (38%), Positives = 70/125 (56%), Gaps = 12/125 (9%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+ F ++GNV+D+AVG I GAAF  +V SLV++IIMPP+GLL+G +DF    + L 
Sbjct: 1   MLKEFKNFLIKGNVIDMAVGFIFGAAFATVVKSLVSNIIMPPVGLLLGNVDFSSLFIALD 60

Query: 63  DAQ-------GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
             +           A  +  GVF  +   F+I+ F +FM IK   K+      P   P P
Sbjct: 61  GKEYVSLADLEKAGAPAIKLGVFFNDFTSFIILGFVMFMMIKGYAKI-----APKEEPLP 115

Query: 116 TKEEV 120
           T +  
Sbjct: 116 TTKVC 120


>UniRef50_C4FVI2 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FVI2_9FIRM
          Length = 128

 Score =  104 bits (260), Expect = 9e-22,   Method: Composition-based stats.
 Identities = 48/133 (36%), Positives = 70/133 (52%), Gaps = 8/133 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            I +EFR F  + N++ LAV VI+G AF  IV+SLV DI MP L  + G       A+  
Sbjct: 3   KIFEEFRGFIAKDNIITLAVAVILGGAFSSIVTSLVNDIFMPILVAVTGQATVSGIALR- 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK-EEPAAAPAPTKEEV 120
                 I    +  G F+Q V +F+I+ F +F+ +K + K   K    P A PA   E+ 
Sbjct: 62  ------IGNTYLGVGNFLQAVINFVIIGFLLFLTLKALGKAQGKDLINPPAPPAGPSEKD 115

Query: 121 LLTEIRDLLKEQN 133
           LL +I + LK++ 
Sbjct: 116 LLQDILNELKKEK 128


>UniRef50_Q1QDU6 Large-conductance mechanosensitive channel n=5 Tax=Bacteria
           RepID=MSCL_PSYCK
          Length = 149

 Score =  104 bits (260), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 54/115 (46%), Positives = 75/115 (65%), Gaps = 11/115 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAV 59
           MS++ EF+EFA++GNV+DLAVGVIIG AF  I  SLV D+IMP +  ++GG I+FK   +
Sbjct: 1   MSMVSEFKEFALKGNVMDLAVGVIIGGAFATITKSLVEDVIMPIVAFIVGGEINFKNMFL 60

Query: 60  TLRDAQGDIPAV----------VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
            L DA   +             V+ YG FI  + +FLI+AF IFM +K++N+L R
Sbjct: 61  ILGDAPEGVARTNDALKAAGIPVLAYGSFITVLINFLILAFIIFMMVKMVNRLRR 115


>UniRef50_B2IVG3 Large conductance mechanosensitive channel protein n=2
           Tax=Cyanobacteria RepID=B2IVG3_NOSP7
          Length = 144

 Score =  102 bits (256), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 43/123 (34%), Positives = 73/123 (59%), Gaps = 9/123 (7%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             +++F+EFA +GNV+DLA+ VIIG AF ++++S V D+IMP +  LIG        VT 
Sbjct: 10  GFLRDFQEFAFKGNVIDLAIAVIIGTAFSRVITSFVEDVIMPLINPLIG--------VTG 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
           ++ +       +  G F+  + DFLI+A  +F+AI+ +    R++E P  + +P+   V+
Sbjct: 62  KEWRTITIGPGIAIGQFLGAIIDFLIIALILFVAIRTLQTFKRQEEVPVES-SPSDANVI 120

Query: 122 LTE 124
             E
Sbjct: 121 AQE 123


>UniRef50_C6R3M2 Large conductance mechanosensitive channel protein n=1 Tax=Rothia
           mucilaginosa ATCC 25296 RepID=C6R3M2_9MICC
          Length = 147

 Score =  102 bits (256), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 44/134 (32%), Positives = 77/134 (57%), Gaps = 14/134 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F +RGNV+DLAVG+I+G AF  +V++LV  ++MP + +L+   +F +F V  +
Sbjct: 24  MLKGFKDFLIRGNVIDLAVGLIMGTAFTAVVNALVQSVLMPAISMLVKSPNFDEFLVFDQ 83

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL----INKLNRKKEEPAAAPAPTKE 118
                     +  GVF+  V +F+++A A++ A+ L    + +L  K +          E
Sbjct: 84  ----------IKVGVFLTAVVNFILIAAAVYFAVVLPVQKLTELAAKNKAEEEEEEEETE 133

Query: 119 EVLLTEIRDLLKEQ 132
             LL EIRD L ++
Sbjct: 134 IALLKEIRDALAKK 147


>UniRef50_A5UVR8 Large-conductance mechanosensitive channel n=2 Tax=Roseiflexus
           RepID=MSCL_ROSS1
          Length = 126

 Score =  102 bits (255), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 59/134 (44%), Positives = 80/134 (59%), Gaps = 14/134 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + + F+ F MRGNV+DLAVGV+IG AF  +V+SLV DI+M  +  LIG  DF    V   
Sbjct: 1   MFEGFKTFVMRGNVIDLAVGVVIGTAFSAVVNSLVNDILMAIVATLIGQPDFSDVLVFG- 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKL---NRKKEEPAAAPAPTKE 118
                     +  G FI  + +FLI++ A++   +  INKL    R+ E P A PAP+ E
Sbjct: 60  ---------AVRLGAFITTIVNFLIISAALYFLVVVPINKLSEFTRRNEPPPAPPAPSAE 110

Query: 119 EVLLTEIRDLLKEQ 132
           E LLTEIRDLL++ 
Sbjct: 111 EKLLTEIRDLLRQN 124


>UniRef50_Q6AAH3 Large conductance mechanosensitive channel n=4 Tax=Bacteria
           RepID=Q6AAH3_PROAC
          Length = 122

 Score =  102 bits (254), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 50/134 (37%), Positives = 70/134 (52%), Gaps = 20/134 (14%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K F++F MRGN+++LAV  I+G AF  +V S    IIM  +G L G  +F  +      
Sbjct: 1   MKGFKDFLMRGNLIELAVAFILGGAFSTVVKSFTT-IIMDLIGKLGGTPNFSGWV----- 54

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLI----NKLNRKKEEPAAAPAPTKE 118
                    +H G FI +V  F +++F I+   IK I     KL R K+EP AAP     
Sbjct: 55  ------PGGVHVGAFITDVISFFVMSFVIYFGLIKPIELATEKLKRTKDEPVAAPTTAD- 107

Query: 119 EVLLTEIRDLLKEQ 132
             LL EIRD L+ +
Sbjct: 108 --LLIEIRDELRSR 119


>UniRef50_A4F7T6 Large-conductance mechanosensitive channel n=3 Tax=Actinomycetales
           RepID=A4F7T6_SACEN
          Length = 158

 Score =  102 bits (254), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 40/133 (30%), Positives = 64/133 (48%), Gaps = 5/133 (3%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F MRGNVVDLAV V++G+AF  +V++    II P +    GG +    ++   
Sbjct: 1   MLKGFKDFLMRGNVVDLAVAVVVGSAFTALVTAFTTSIIKPVIAA-TGGGNVTGLSI--- 56

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK-LNRKKEEPAAAPAPTKEEVL 121
                    ++ +   I  V  F I A  ++    L  K L  ++E          +  L
Sbjct: 57  QLVAGNQQSIIDFAQVINAVITFFITAAVVYFIFVLPMKTLKERRERGKETEVAPTDVEL 116

Query: 122 LTEIRDLLKEQNN 134
           L EIRDLL+ +  
Sbjct: 117 LLEIRDLLRREQG 129


>UniRef50_Q5SKL6 Large-conductance mechanosensitive channel n=2 Tax=Thermus
           thermophilus RepID=Q5SKL6_THET8
          Length = 124

 Score =  101 bits (253), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 48/135 (35%), Positives = 72/135 (53%), Gaps = 15/135 (11%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + ++ ++F MRGNVVDLAV VIIG AF ++VSSLVAD+I P +G L G  DF    +   
Sbjct: 1   MWRDLKDFLMRGNVVDLAVAVIIGTAFSQVVSSLVADVITPLIGALGGVPDFSGIRL--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN----KLNRKKEEPAAAPAPTKE 118
                     +  G F+  + +FLIV   ++  + +      K  RK  +    P P +E
Sbjct: 58  --------GPIALGRFLNALLNFLIVGTTVYFLVVVPMREAQKRLRKPPQETPPPEPPEE 109

Query: 119 EVLLTEIRDLLKEQN 133
             LL EI + L+++ 
Sbjct: 110 IRLLREILEELRKKT 124


>UniRef50_C7H9Q8 Large conductance mechanosensitive channel protein n=1
           Tax=Faecalibacterium prausnitzii A2-165
           RepID=C7H9Q8_9FIRM
          Length = 152

 Score =  101 bits (252), Expect = 7e-21,   Method: Composition-based stats.
 Identities = 44/101 (43%), Positives = 63/101 (62%), Gaps = 8/101 (7%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
              +EF+ FAMRGNV+D+AVGV++G+AF  IV+SLV D+I P +GL     DF +  V +
Sbjct: 11  KFFEEFKAFAMRGNVLDMAVGVVVGSAFTAIVNSLVGDVINPLIGLFFNN-DFSEVVVKI 69

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL 102
            D       V +  G FI  + +FLIVAF +F+ +K  N +
Sbjct: 70  GD-------VDLKIGSFISAIINFLIVAFVLFLVLKAFNAV 103


>UniRef50_Q8DHB2 Large-conductive mechanosensitive channel n=1
           Tax=Thermosynechococcus elongatus BP-1
           RepID=Q8DHB2_THEEB
          Length = 140

 Score =  100 bits (250), Expect = 1e-20,   Method: Composition-based stats.
 Identities = 41/114 (35%), Positives = 67/114 (58%), Gaps = 11/114 (9%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
             +EFREFA++GNV+DLA+ V++G AF +IV+S+V D+IMP +  LI G D+++  +   
Sbjct: 14  FWQEFREFALKGNVIDLAIAVVVGGAFSRIVTSVVEDLIMPLVNPLIPGGDWRELTL--- 70

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK-LNRKKEEPAAAPAP 115
                     M  G F+ ++ DF ++A ++F+ +KLI   L  +   P     P
Sbjct: 71  -------GSGMRIGKFLGSLLDFGVIALSLFILLKLILPFLPNRPPAPEQRQCP 117


>UniRef50_A1RBS3 Large conductance mechanosensitive channel protein n=7
           Tax=Actinomycetales RepID=A1RBS3_ARTAT
          Length = 154

 Score =  100 bits (249), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 40/134 (29%), Positives = 71/134 (52%), Gaps = 10/134 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + K F++F +RGNV++LA+ V+IG+AF  +V++   +II P +    GG++       + 
Sbjct: 1   MFKGFKDFILRGNVIELAIAVVIGSAFTALVTAFTNNIINPVIAAA-GGMNADGLGFKIW 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMA-IKLINKLN-----RKKEEPAAAPAPT 116
           +   + PA +++ G  +  +  F+I A  ++   +  +NK+N     R   E        
Sbjct: 60  E---NNPATLVNIGAVLTALVTFVITAAVVYFIFVAPMNKINSLVKDRLSTEEPEEEPLP 116

Query: 117 KEEVLLTEIRDLLK 130
            +  LL EIRDLLK
Sbjct: 117 ADTALLAEIRDLLK 130


>UniRef50_B1XK85 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=B1XK85_SYNP2
          Length = 145

 Score =  100 bits (249), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 46/104 (44%), Positives = 66/104 (63%), Gaps = 7/104 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S   +F+ F MRGNV+DLAV V+IG AFG+IV+SLVADII P +            +   
Sbjct: 6   SFWSDFQAFIMRGNVIDLAVAVVIGGAFGQIVNSLVADIITPAI-------LQPALSAAN 58

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK 105
            DA G++    + YG+F+  V +FL++AFAIF+ I+ I K+ R+
Sbjct: 59  LDALGELSFNGIKYGLFLAAVINFLVIAFAIFLVIRAIEKMQRR 102


>UniRef50_Q8EW76 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           penetrans RepID=Q8EW76_MYCPE
          Length = 215

 Score =   99 bits (248), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 39/110 (35%), Positives = 60/110 (54%), Gaps = 9/110 (8%)

Query: 4   IKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG--------IDF 54
            KEF++    RGN++DLAV +IIG AF  IV+SLV DIIMP +G   G         +D 
Sbjct: 19  WKEFKKLVSSRGNLIDLAVALIIGTAFTAIVTSLVNDIIMPLIGAAAGKSLSELVWYLDI 78

Query: 55  KQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
                 L +   +  A+++ YG F+Q + +F I+A  +F  +K    + +
Sbjct: 79  NNQPHFLPNGDINPQAIIIKYGNFLQVIINFFIIALTMFSVVKAYLSIRK 128


>UniRef50_C9RJE4 Large conductance mechanosensitive channel protein n=1
           Tax=Fibrobacter succinogenes subsp. succinogenes S85
           RepID=C9RJE4_FIBSS
          Length = 149

 Score = 99.5 bits (247), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 67/143 (46%), Positives = 93/143 (65%), Gaps = 14/143 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI---GGIDFKQFA 58
           S+I+EF+ FA +GN+VD+A+G+IIGAAFGKIV+S V DI+MP +  +I   GG +  +  
Sbjct: 9   SLIEEFKAFAFKGNIVDMAIGIIIGAAFGKIVNSFVNDIVMPLVTAVIAKCGGQNAGEGI 68

Query: 59  VTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK----LINKLNRKK-----EEP 109
            TL     +   + + YG FI  V +FLIVAFA+F+ +K     +  + +KK       P
Sbjct: 69  KTLVYTTSE--GIAIPYGTFIGEVLNFLIVAFAVFLMMKKFLGFMQNMRKKKEAEAAAAP 126

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQ 132
           AA PAP+ EE LLTEIRDLLK +
Sbjct: 127 AAPPAPSAEEKLLTEIRDLLKNK 149


>UniRef50_P73553 Large-conductance mechanosensitive channel n=2 Tax=Chroococcales
           RepID=MSCL_SYNY3
          Length = 145

 Score = 98.7 bits (245), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 11/122 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
              ++F++F +RGNVVDLAV V+IG AF  IV++ VA ++   L  ++      Q     
Sbjct: 11  GFWRDFKDFILRGNVVDLAVAVVIGGAFTSIVNAFVAWLMAVLLQPVLDQAGVSQL---- 66

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                    + +  G  +  + +FLI+AF IF+ IK I K+ RKK       A  + + +
Sbjct: 67  -------QDLPLGLGELVIAIINFLIIAFVIFLIIKAIEKMQRKKAVEEEIVAEAQPDPV 119

Query: 122 LT 123
           L 
Sbjct: 120 LE 121


>UniRef50_C1AX17 Large-conductance mechanosensitive channel n=2 Tax=Rhodococcus
           RepID=C1AX17_RHOOB
          Length = 155

 Score = 98.0 bits (243), Expect = 9e-20,   Method: Composition-based stats.
 Identities = 41/130 (31%), Positives = 68/130 (52%), Gaps = 4/130 (3%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F +RGNV+DLAV V++GAAF  IV+S   ++I P + +  G  D         
Sbjct: 1   MLKGFKDFLLRGNVLDLAVAVVVGAAFTAIVTSFTNNVINPLIAVAGGANDLGWGY---- 56

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               D PA  ++ G  I  V +F+I+A  ++  + +     +K+     A     E  LL
Sbjct: 57  QILADNPATFINIGAVITAVINFVIIAAVVYFILIVPANAAKKRFITEPADKKASEADLL 116

Query: 123 TEIRDLLKEQ 132
            +IRD+L+  
Sbjct: 117 IQIRDILEAS 126


>UniRef50_Q025U4 Large conductance mechanosensitive channel protein n=1
           Tax=Candidatus Solibacter usitatus Ellin6076
           RepID=Q025U4_SOLUE
          Length = 136

 Score = 97.6 bits (242), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 43/122 (35%), Positives = 66/122 (54%), Gaps = 3/122 (2%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK F+EF ++ NV+ LAV VI+G A GK+VSSL AD+IMP + L++   D++     L 
Sbjct: 1   MIKGFKEFLLKNNVLALAVAVIVGGAVGKVVSSLAADVIMPVISLVLPAGDWRTAKFVLG 60

Query: 63  ---DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEE 119
                 G      ++YG F  +V DFLI+A  +++  K + K       P     P  +E
Sbjct: 61  KTVGPDGKETLNTLNYGSFFGSVVDFLIIALVVYLMTKALIKEAPAPAPPPTKNCPRCKE 120

Query: 120 VL 121
            +
Sbjct: 121 AI 122


>UniRef50_B1V916 Putative large-conductance mechanosensitive channel n=1
           Tax=Candidatus Phytoplasma australiense
           RepID=B1V916_PHYAS
          Length = 134

 Score = 97.2 bits (241), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 49/129 (37%), Positives = 74/129 (57%), Gaps = 10/129 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG-GIDFKQFAV 59
           M+  + F+ F  RGNV++LAV V+IG  F KIVSSLVADI+MPP  LL       +    
Sbjct: 1   MTFFQGFKNFITRGNVINLAVAVVIGQLFSKIVSSLVADIMMPPFSLLFNETKGLQGLKW 60

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL---NRKKEEPAAAPAPT 116
            +++       V M+YG+F+QN+ +F+I +FAI++ + + ++      K E      +  
Sbjct: 61  CIKE------DVYMNYGIFLQNILEFVIFSFAIYLILTIFSRTKLEKPKSELKLILESLQ 114

Query: 117 KEEVLLTEI 125
           KE  LL EI
Sbjct: 115 KEITLLQEI 123


>UniRef50_D0P2C5 Large Conductance Mechanosensitive Ion Channel (MscL) Family n=2
           Tax=Phytophthora infestans T30-4 RepID=D0P2C5_PHYIN
          Length = 191

 Score = 97.2 bits (241), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 41/134 (30%), Positives = 76/134 (56%), Gaps = 17/134 (12%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-GGIDFKQFAV- 59
           +++ +F+EF  +GN++++AVG+I+G++F  I++SLV DI+ P + L    GI    + V 
Sbjct: 35  ALLTDFQEFIQQGNMLNMAVGLILGSSFSAILNSLVVDILSPIISLFTERGIANHYWPVR 94

Query: 60  --------------TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK 105
                         T ++A+ D  AV ++YG+FI+N+ +F+I A  +F+A+K   +   K
Sbjct: 95  CPSTTTVCSGETWQTWKEAR-DAGAVTINYGLFIENIMNFVINALFLFIAVKKALEFVFK 153

Query: 106 KEEPAAAPAPTKEE 119
            +       P  +E
Sbjct: 154 LKVGVKKQCPYCKE 167


>UniRef50_Q2NK99 Large-conductance mechanosensitive channel n=2 Tax=Candidatus
           Phytoplasma asteris RepID=Q2NK99_AYWBP
          Length = 145

 Score = 95.7 bits (237), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 50/140 (35%), Positives = 74/140 (52%), Gaps = 13/140 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGID-FKQFAV 59
           +   K F+ F  RGNV++LAV V+IG  F KIVSSLVADIIMP   LL       K    
Sbjct: 12  LEFAKGFKAFIARGNVINLAVAVVIGQLFAKIVSSLVADIIMPLFSLLFNYTGALKDLKF 71

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAA------P 113
           T++          + YG F+Q + +FL+++F I+  + L++  N  ++E           
Sbjct: 72  TIK------ANTYLCYGNFLQTILEFLLLSFIIYTILTLMSWKNPLQKEKTDKNMLLLQQ 125

Query: 114 APTKEEVLLTEIRDLLKEQN 133
           +  KE  LL EI+++LK   
Sbjct: 126 SLNKEIALLEEIKNILKSNK 145


>UniRef50_C7QC56 Large conductance mechanosensitive channel protein n=1
           Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QC56_CATAD
          Length = 174

 Score = 95.3 bits (236), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 9/104 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGI-DFKQFAVTLR 62
           +  F +F +RGNV+ LAVGV+IGAAF  +V+S     + P +G   GGI D+ +   TL 
Sbjct: 1   MNGFVKFVVRGNVIGLAVGVVIGAAFAAMVTSFTTAFLTPLIGWATGGIGDYSKKVFTLG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRK 105
                       YG F+     FL+ A  ++  I L +NKL  +
Sbjct: 61  K-------TPFPYGTFVNAGISFLLTAATLYFLIVLPVNKLTEE 97


>UniRef50_Q9P639 Related to large-conductance mechanosensitive channel n=8
           Tax=Leotiomyceta RepID=Q9P639_NEUCR
          Length = 373

 Score = 94.1 bits (233), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 36/127 (28%), Positives = 66/127 (51%), Gaps = 16/127 (12%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-------------- 49
            ++F  FA +GNV+++A G+I+   F  +V+S V+DI++PP+ +L+              
Sbjct: 28  WEDFVGFAFQGNVLEIAFGLILATMFTALVTSFVSDIVLPPISVLLPLNKNLEEKFAVLR 87

Query: 50  -GGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
            G    ++   TL+ AQ D  AVVM YG F+  + +F+ V F+++    +   +++    
Sbjct: 88  SGANHPEEGYNTLKQAQAD-GAVVMAYGFFMNRLLNFMGVGFSLYSIASIYQWMSKDPII 146

Query: 109 PAAAPAP 115
               P P
Sbjct: 147 KKTVPCP 153


>UniRef50_A1SES5 Large-conductance mechanosensitive channel n=1 Tax=Nocardioides sp.
           JS614 RepID=A1SES5_NOCSJ
          Length = 129

 Score = 92.6 bits (229), Expect = 4e-18,   Method: Composition-based stats.
 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 12/133 (9%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  F+ F +RGN+V+LAV  ++ AA    V +    +IM  +G   G  DF  +      
Sbjct: 1   MTGFKNFILRGNLVELAVAFVMAAA-FATVVTATVGLIMDLIGKAGGTPDFSDYVWNG-- 57

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLT 123
                    +  G ++  +  FLI+A  ++  I +     +++  P+  P   ++  LL 
Sbjct: 58  ---------ISIGAWLTALISFLIIAAVVYFFIVVPYTKAKERYFPSPEPGTPEDVKLLE 108

Query: 124 EIRDLLKEQNNRS 136
           EIRDLL  Q  RS
Sbjct: 109 EIRDLLATQQGRS 121


>UniRef50_B3PMZ4 Large-conductance mechanosensitive channel, putative n=2
           Tax=Mycoplasma RepID=B3PMZ4_MYCA5
          Length = 152

 Score = 91.8 bits (227), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 40/133 (30%), Positives = 65/133 (48%), Gaps = 19/133 (14%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           K+ ++   +GN+  LA+ V+IGAAFG +VSSL  D+IM  +  +      +   V     
Sbjct: 18  KDAKKSITKGNMFMLAIAVLIGAAFGAVVSSLANDVIMAAIAKIWNASSVEDLKV----- 72

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI---------NKLNRKKEEPAAAPAP 115
                A  +  G F+  +  F+IVA  +F  + ++          K  +   EP A P P
Sbjct: 73  -----AGTIKIGKFLAALIQFVIVATVVFFTLLIVFSIKNAIEYAKAKKMPIEPEAEPTP 127

Query: 116 TKEEVLLTEIRDL 128
           T EE++L E++ L
Sbjct: 128 TNEELILAELKKL 140


>UniRef50_B8MJW8 Ion channel, putative n=3 Tax=Trichocomaceae RepID=B8MJW8_TALSN
          Length = 235

 Score = 91.0 bits (225), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 38/106 (35%), Positives = 56/106 (52%), Gaps = 17/106 (16%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL--------------- 48
              F +FAMR NV+++A+G++IG AF K+V+S V+D+I+P + LL               
Sbjct: 72  WDGFVDFAMRDNVLEVAIGLMIGQAFTKVVTSFVSDVILPVISLLPFIHRNLDEKFSVLR 131

Query: 49  -IGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF 93
                D      TL  A+ D  A+VM YG F+ NV  FL V   ++
Sbjct: 132 KGPNYDLAGGYNTLAQARDD-GALVMAYGAFLNNVMSFLGVGIVLY 176


>UniRef50_A6GYI6 Large-conductance mechanosensitive channel n=4
           Tax=Flavobacteriaceae RepID=MSCL_FLAPJ
          Length = 138

 Score = 90.7 bits (224), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 56/138 (40%), Positives = 81/138 (58%), Gaps = 7/138 (5%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M    +F+   M+G+V+ LA  V+IG AFGKIV S V DIIMP +G+L GG+DF    + 
Sbjct: 1   MGFFADFKASLMKGDVLSLATAVVIGGAFGKIVGSAVDDIIMPIVGVLTGGVDFTTKFIA 60

Query: 61  LRD-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
           L         A     A  + YG  +Q + +F+I++F IF+ ++   K  +K+E    AP
Sbjct: 61  LNGQSYADLAAAKTAGAACLTYGNLVQAIINFIIISFFIFVVLRAAEKAKKKEEAAPTAP 120

Query: 114 APTKEEVLLTEIRDLLKE 131
           A   +E LLT+IRDLLK+
Sbjct: 121 AGPSQEELLTQIRDLLKK 138


>UniRef50_Q5HPJ2 Large-conductance mechanosensitive channel n=9 Tax=Bacteria
           RepID=MSCL_STAEQ
          Length = 116

 Score = 87.2 bits (215), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 60/129 (46%), Positives = 89/129 (68%), Gaps = 13/129 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNV+DLA+ V++GAAF KIV+SLV  IIMP +G L G ++F +      
Sbjct: 1   MLKEFKEFALKGNVLDLAIAVVMGAAFNKIVTSLVQYIIMPLIGKLFGSVNFAE------ 54

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               D     + YG+FIQ++ DF+I+AFA+F+ +K+ N + +K+E+       T   VLL
Sbjct: 55  ----DWSFWGIKYGLFIQSIIDFIIIAFALFIFVKIANTVMKKEEKEEEVEENT---VLL 107

Query: 123 TEIRDLLKE 131
           TEIRDLLK+
Sbjct: 108 TEIRDLLKK 116


>UniRef50_Q98B35 Large-conductance mechanosensitive channel n=1 Tax=Mesorhizobium
          loti RepID=Q98B35_RHILO
          Length = 87

 Score = 86.0 bits (212), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 38/61 (62%), Positives = 48/61 (78%)

Query: 3  IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
          ++KEF+EF  +GNV+DLAVGVIIGAAFGKIV SLV DIIMP +G + GG+DF  + + L 
Sbjct: 1  MLKEFQEFISKGNVMDLAVGVIIGAAFGKIVDSLVNDIIMPIVGAIFGGLDFNNYFLGLP 60

Query: 63 D 63
           
Sbjct: 61 Q 61


>UniRef50_D2S4B1 Large conductance mechanosensitive channel protein n=1
           Tax=Geodermatophilus obscurus DSM 43160
           RepID=D2S4B1_9ACTO
          Length = 136

 Score = 86.0 bits (212), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 37/110 (33%), Positives = 62/110 (56%), Gaps = 7/110 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           +++  FR FA  G++VDLAVG+ IGAAF  +V SLV D+I+P +  + G  +F    +T+
Sbjct: 3   TLLTNFRNFAFSGSLVDLAVGLAIGAAFAAVVESLVGDVILPLVAAIFGAPNFDVLVLTV 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA 111
             AQ       + YG F+  +  FL++A  I + ++ I +   ++   A 
Sbjct: 63  NGAQ-------IRYGSFLTALVSFLLLALTIMLLVQAIRRATGRETAGAQ 105


>UniRef50_UPI0001B45932 large conductance mechanosensitive channel n=1 Tax=Mycobacterium
           intracellulare ATCC 13950 RepID=UPI0001B45932
          Length = 139

 Score = 86.0 bits (212), Expect = 4e-16,   Method: Composition-based stats.
 Identities = 28/132 (21%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK F+ F MRG+V+ +A+G+++  AF  +V +    +I P +  +  G  F    +  +
Sbjct: 1   MIKGFKSFVMRGDVITVAIGLVVALAFSNLVKAFTDSVINPLVAAVQPGTKF---GLGWQ 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA---AAPAPTKEE 119
                  A  +  G FI  +  F++   A++  I +  K  + +         PA     
Sbjct: 58  LGDAGNKATFLDIGSFISAIIYFVVFMTAVYFMIVVPYKHIQARRGVTVFGEEPATKACA 117

Query: 120 VLLTEIRDLLKE 131
              ++I +  ++
Sbjct: 118 ECKSDIPEAARK 129


>UniRef50_D1YYF3 Putative large-conductance mechanosensitive channel n=1
           Tax=Methanocella paludicola SANAE RepID=D1YYF3_METPS
          Length = 101

 Score = 85.3 bits (210), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 7/100 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M I+++F+EF     V+ LAV  I+G A   ++ +LV DIIMP +G LI G         
Sbjct: 1   MGIMQDFKEFLNEYKVMGLAVAFIMGVAATALIQALVNDIIMPIIGRLIPGG-------A 53

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN 100
            + A  DI  ++  +G F+  V +F+I+AF +F+  K I 
Sbjct: 54  WQTATLDIAGMLFKWGDFLSQVINFVIIAFVVFLIAKFIM 93


>UniRef50_A7HBZ5 Large conductance mechanosensitive channel protein n=1
           Tax=Anaeromyxobacter sp. Fw109-5 RepID=A7HBZ5_ANADF
          Length = 139

 Score = 84.9 bits (209), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 41/113 (36%), Positives = 62/113 (54%), Gaps = 7/113 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            + KEFREF ++ NV+ LA GV+IGAA GK+VS +V  ++MP +GLL+ G D        
Sbjct: 13  GLAKEFREFLLKQNVIALAAGVVIGAAIGKVVSGIVDFVVMPVVGLLLPGQD------EW 66

Query: 62  RDAQGDI-PAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
           R A+ DI     + YG  +  + +F I+A  +F+ +K   +         A P
Sbjct: 67  RQAKLDIGGGNAIGYGEVVGRLVEFGIIALVVFLVLKAFVRAPPPPAPTKACP 119


>UniRef50_D2ARQ8 Large conductance mechanosensitive channel protein n=9 Tax=Bacteria
           RepID=D2ARQ8_STRRD
          Length = 142

 Score = 84.5 bits (208), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 38/123 (30%), Positives = 62/123 (50%), Gaps = 16/123 (13%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI--GGIDFKQFAVTL 61
           +  F++F MRGN+V+LAV V++GA F  +V +LV D+I P +  +   GG DF Q+  T+
Sbjct: 1   MGGFKKFLMRGNLVELAVAVVVGATFSGLVQALVKDLITPLIAAITGGGGPDFSQYVFTV 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK-------LNRKKEEPAAAPA 114
             A+         YG FI ++  FLI+A  I+  + +           ++K  E      
Sbjct: 61  NGAK-------FMYGDFINHLLSFLIIAAVIYWLVVMPMTRVIAFFDRDKKATEKECPEC 113

Query: 115 PTK 117
            + 
Sbjct: 114 LSD 116


>UniRef50_C5BF23 Putative uncharacterized protein n=1 Tax=Edwardsiella ictaluri
           93-146 RepID=C5BF23_EDWI9
          Length = 77

 Score = 84.1 bits (207), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 45/72 (62%), Positives = 53/72 (73%), Gaps = 1/72 (1%)

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
           +R A G  PA+V +YG FIQ +FDF+IV FAIFMAIK INKL R+K      PAP+ E V
Sbjct: 1   MRKAIGSTPALVANYGQFIQAIFDFIIVTFAIFMAIKPINKLRRQKTA-ETPPAPSAEAV 59

Query: 121 LLTEIRDLLKEQ 132
           LLTEIR+LLK Q
Sbjct: 60  LLTEIRELLKAQ 71


>UniRef50_Q0IDN4 Large conductance mechanosensitive channel protein n=2
           Tax=Synechococcus RepID=Q0IDN4_SYNS3
          Length = 127

 Score = 83.0 bits (204), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 38/135 (28%), Positives = 68/135 (50%), Gaps = 17/135 (12%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            +  +F+ F  +GNVVDLA+ V+I  AFGK+V+++V  ++   L   +   +        
Sbjct: 6   GLFADFKAFINKGNVVDLAIAVVIAGAFGKVVATVVTLVMTNALEPALKAANV------- 58

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
            D+    PA     G  I  + +FL++AF  F+ +K I   +++K+E  A   P  +  L
Sbjct: 59  -DSINSWPA-----GTVIVAIINFLVIAFVCFLIVKSIE-ASKRKQEVIAETKPDPQAQL 111

Query: 122 ---LTEIRDLLKEQN 133
              +T + D L+ + 
Sbjct: 112 ASAMTRLTDALERKG 126


>UniRef50_B3QZY1 Large-conductance mechanosensitive channel n=1 Tax=Candidatus
           Phytoplasma mali AT RepID=B3QZY1_PHYMT
          Length = 139

 Score = 82.6 bits (203), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 35/113 (30%), Positives = 63/113 (55%), Gaps = 6/113 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG--IDFKQFAV 59
           +  K F++F  +GNV++L++  +I   F KIV+SL +DIIMP + LL      DF     
Sbjct: 10  NFTKGFKKFINKGNVLNLSIAFVISQLFSKIVNSLSSDIIMPFMNLLFSSDKNDFSDLRF 69

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAA 112
            +         + ++YG F++ VF+FLI++F I++ + ++ + N   E+    
Sbjct: 70  RIT----SNSNIYIYYGKFLKTVFEFLIMSFFIYIILIIVFRQNLNSEKVNIE 118


>UniRef50_B8MKR4 Large-conductance mechanosensitive channel, putative n=1
           Tax=Talaromyces stipitatus ATCC 10500 RepID=B8MKR4_TALSN
          Length = 288

 Score = 82.6 bits (203), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 17/107 (15%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-------------- 49
              F +FA+R NV+++A+G+II AAF K+V+S V+D+ +P + LL               
Sbjct: 23  WDGFWDFALRDNVLEVAIGLIIAAAFTKVVNSFVSDLFLPIISLLPFLNRNLEDKFAVLR 82

Query: 50  GGIDFKQF---AVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF 93
            G  +  +        +   D  A+VM YG F+    +F+ +   ++
Sbjct: 83  KGKHYSDWGPGGYNTLEQARDDGALVMAYGAFLDKFINFVGIGLTLY 129


>UniRef50_B6HL82 Pc21g07880 protein n=6 Tax=Trichocomaceae RepID=B6HL82_PENCW
          Length = 201

 Score = 82.2 bits (202), Expect = 4e-15,   Method: Composition-based stats.
 Identities = 37/128 (28%), Positives = 60/128 (46%), Gaps = 17/128 (13%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGL--------------LI 49
              F  FA R NV+++A+G+II  AF K+V+S V D+++P + L              L 
Sbjct: 26  WDGFINFAARDNVLEVALGLIIANAFTKVVTSFVTDMVLPIVSLLPFLNRNMDQKFAVLS 85

Query: 50  GGIDFK--QFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
            G +F       TL  A+ D  A+V+ YG F++   +FL V+  ++    L   + + K 
Sbjct: 86  KGPNFDQQNGYNTLLQARED-GALVLAYGAFMETALNFLGVSLTLYAVGHLYMLIFQDKI 144

Query: 108 EPAAAPAP 115
                  P
Sbjct: 145 IKPTVRCP 152


>UniRef50_A7I494 Large-conductance mechanosensitive channel-like protein n=3
           Tax=Genera incertae sedis RepID=A7I494_METB6
          Length = 125

 Score = 81.8 bits (201), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 7/101 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M   +EF  F  +  V+ LAV  +IG A   +V++LV DIIMP + +L  G         
Sbjct: 25  MGFKEEFLLFLKQYQVIGLAVAFVIGTAATAMVNALVKDIIMPVVSVLTPGGQ------- 77

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
            + A   +  + +  G F+  V DFLI+A  +F  +K + K
Sbjct: 78  WQTAVLAVGPINLLAGDFLSAVLDFLIIALVVFFLVKYVMK 118


>UniRef50_Q83MR6 Large-conductance mechanosensitive channel n=2 Tax=Tropheryma
          whipplei RepID=Q83MR6_TROWT
          Length = 207

 Score = 81.4 bits (200), Expect = 7e-15,   Method: Composition-based stats.
 Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 1/96 (1%)

Query: 3  IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
          +   FR+F  R NVVDL+  V+IGAA   +++++V DI  P +   +     +  ++ L 
Sbjct: 5  MFAGFRDFIARRNVVDLSAAVVIGAASTAVINAIVDDIFSPLISAALSSSKIEN-SLVLT 63

Query: 63 DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL 98
                  V + +G  +  +  F++V+  ++  I L
Sbjct: 64 IPTLSHGHVQLKFGTVLLALIKFVLVSAVVYFVIIL 99


>UniRef50_Q6KH26 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           mobile RepID=Q6KH26_MYCMO
          Length = 151

 Score = 81.4 bits (200), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 45/139 (32%), Positives = 73/139 (52%), Gaps = 20/139 (14%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG--GIDFKQFAVTLRD 63
           E +    RGN++ LAVG+++G  FG +V+S   DI++  +G+ I   GI+   F+     
Sbjct: 19  EAKSALKRGNILMLAVGLLLGTVFGALVASFANDILLGAIGIGINALGININNFS----- 73

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIV------AFAIFMAIKLINKLNRKKEEPA----AAP 113
              D+    + YG FI  +  F+IV      A  I+  I+ I   N KK+ P     AAP
Sbjct: 74  ---DLSFQTIRYGNFISALLTFIIVSLFIFFALFIYFVIRNIRLDNLKKKYPERYVVAAP 130

Query: 114 APTKEEVLLTEIRDLLKEQ 132
            P+ +E++L E+R L + +
Sbjct: 131 KPSTDELILEELRTLNRAK 149


>UniRef50_A3Z5P9 Possible large-conductance mechanosensitive channel mscL n=1
           Tax=Synechococcus sp. RS9917 RepID=A3Z5P9_9SYNE
          Length = 102

 Score = 81.0 bits (199), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 32/103 (31%), Positives = 57/103 (55%), Gaps = 13/103 (12%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           +   +F++F  +GNVVDLAV V+IG AFGK+V ++V+ ++   L  ++   +        
Sbjct: 6   TFFADFKDFINKGNVVDLAVAVVIGGAFGKVVDAVVSLVMGNILEPVLKAANV------- 58

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
            D+    PA     G  I  + +FL++AF +F+ ++ I  + R
Sbjct: 59  -DSIAAWPA-----GSVIVALINFLVIAFVVFLIVRAIEAMRR 95


>UniRef50_A4RKI5 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
           RepID=A4RKI5_MAGGR
          Length = 175

 Score = 79.9 bits (196), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 22/140 (15%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI------------- 49
           +   F +FA++GN++++A G+I+ AAF  I++SLV+DI++PPL +L              
Sbjct: 32  VWDGFLDFALQGNILEIAFGLILAAAFTSIINSLVSDILLPPLSVLFPLNKNLDEKFAVL 91

Query: 50  -GGIDFK--QFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK 106
             G +F              +  AVVM +G F+  V +FL +  +++    L    +  +
Sbjct: 92  KPGPNFDPANGGYPTIQLAQEDSAVVMAWGSFVNKVLNFLGLGVSLYALAGLYQYFSNGR 151

Query: 107 EEPAAAPAPTKEEVLLTEIR 126
              +   A       L E+R
Sbjct: 152 SAASTVQAG------LMELR 165


>UniRef50_Q0I7U4 Large-conductive mechanosensitive channel n=2 Tax=Synechococcus
           RepID=Q0I7U4_SYNS3
          Length = 157

 Score = 79.1 bits (194), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 27/103 (26%), Positives = 55/103 (53%), Gaps = 8/103 (7%)

Query: 3   IIKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             +EF +F   +GN ++LA+ V++G  F ++V +L  D++MP L  LI    ++++ +  
Sbjct: 43  WFREFTDFFFQKGNALNLAIAVVVGTQFQQVVDALTQDLLMPLLNPLIRNGGWEEWVLPY 102

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
              +       +  G  +  + + LIV + +F+ +K IN+  R
Sbjct: 103 AGGE-------LLLGKAMNVLLNSLIVGWVLFLIVKAINRSQR 138


>UniRef50_A5GNA8 Large-conductance mechanosensitive channel n=1 Tax=Synechococcus
           sp. WH 7803 RepID=A5GNA8_SYNPW
          Length = 117

 Score = 79.1 bits (194), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 8/105 (7%)

Query: 4   IKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++EF EF   +GN ++LA+ V++G  F +IV+++  D++MP L  L+ G +++   +   
Sbjct: 1   MREFTEFFFQKGNALNLAIAVVVGTQFQQIVNAISKDLLMPLLNPLVRGGNWQNLVIPYY 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
                     +  G     + + LIV +A+F  IK IN+  R  E
Sbjct: 61  GGD-------LAIGKIFDVILNSLIVGWALFFIIKAINRSQRTLE 98


>UniRef50_A5Z9U3 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
           ATCC 27560 RepID=A5Z9U3_9FIRM
          Length = 101

 Score = 78.3 bits (192), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 29/77 (37%), Positives = 40/77 (51%), Gaps = 7/77 (9%)

Query: 42  MPPLGLLIGGIDFKQFAVTLRDA-------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFM 94
           MP + LL G IDF    + L               A  ++YG FI  + +FLI+AF +FM
Sbjct: 1   MPVITLLTGKIDFSNLFIALDGGSYKTLAEAQKAGAATLNYGTFISGLINFLIMAFVVFM 60

Query: 95  AIKLINKLNRKKEEPAA 111
            +K +NKL RK+E   A
Sbjct: 61  IVKFMNKLRRKEEPAPA 77


>UniRef50_D0P2C6 Large conductance mechanosensitive channel, putative n=2
           Tax=Phytophthora infestans T30-4 RepID=D0P2C6_PHYIN
          Length = 158

 Score = 78.3 bits (192), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 31/120 (25%), Positives = 62/120 (51%), Gaps = 7/120 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGV--IIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV 59
           +++ +F++F  +GN++D+A G    I  ++G     LVA + +  LG  +     K F +
Sbjct: 14  ALLTDFQDFIQQGNMIDMATGASPTITGSYGAQQLPLVAQVRLGRLGNKVPDNKMKAFVL 73

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEE 119
            ++D       V ++YG+F++N   F I A  +F+A+K + ++  K+        P  +E
Sbjct: 74  LVKDG-----VVTINYGLFMENAVTFFINAIFLFLAVKKVFEVVFKRSVLVKKQCPHCKE 128


>UniRef50_B2VVD2 Putative uncharacterized protein n=1 Tax=Pyrenophora
           tritici-repentis Pt-1C-BFP RepID=B2VVD2_PYRTR
          Length = 242

 Score = 78.3 bits (192), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 17/118 (14%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL------------- 48
           S  + F  FA+R NV+++AVG+I+ ++F    ++LV+DII+P + LL             
Sbjct: 25  SAWESFSNFALRDNVLEVAVGLILASSFTACANALVSDIILPIISLLPFLSRTLDTKFVL 84

Query: 49  ---IGGIDFKQFAVTLRDAQG-DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL 102
                  +    A     AQ  D  AVV+ YG F+  +  F IVA A+++   +  + 
Sbjct: 85  LRHGPNSNSTISAGYNTPAQAVDDGAVVLAYGHFLDKIVRFAIVALALWVIANVYGRF 142


>UniRef50_D1J7K2 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           hominis ATCC 23114 RepID=D1J7K2_MYCHP
          Length = 172

 Score = 76.8 bits (188), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 38/134 (28%), Positives = 67/134 (50%), Gaps = 12/134 (8%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           + ++   RGN+  LA+G+++GA+FG +VSSL  D+IM  +   +G  +   + V      
Sbjct: 19  DAKKIVSRGNMFMLAIGLLLGASFGALVSSLANDVIMSAITKAVGMKNLDAWVV-WPGIH 77

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-----------NKLNRKKEEPAAAPA 114
                  +  G F+  +  F+IV+  IF+ + ++            K N  +EE    P 
Sbjct: 78  ATKETGGIFIGKFLGALIQFIIVSTFIFIGLMIVFTIKNSILYAKAKKNPIEEEIKEEPI 137

Query: 115 PTKEEVLLTEIRDL 128
           PT EE++L E++ L
Sbjct: 138 PTTEELILNELKKL 151


>UniRef50_Q2FQE0 Large conductance mechanosensitive channel protein n=4
           Tax=Euryarchaeota RepID=Q2FQE0_METHJ
          Length = 108

 Score = 76.4 bits (187), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 7/108 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M++I EF +F     VV LA+  I+G A   +V S V ++IMP + ++    D       
Sbjct: 8   MTLISEFLDFLKEYKVVALAIAFIMGVAATALVKSFVDNLIMPFVSVITPSGD------- 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
            ++A   I  V +  G F     +F+I+A  +FM  K + K  + +++
Sbjct: 61  WKEAVLAIGPVQLGIGPFAAECINFIIIALVVFMVAKYVMKEEKVEKK 108


>UniRef50_C7PYG5 Large conductance mechanosensitive channel protein n=1
          Tax=Catenulispora acidiphila DSM 44928
          RepID=C7PYG5_CATAD
          Length = 145

 Score = 75.3 bits (184), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 7/95 (7%)

Query: 4  IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
          +  FR+F +RGN+VDLAV V++G+ F  +V   VA  I P LG +    +F   + T+R 
Sbjct: 1  MSGFRKFILRGNLVDLAVAVVVGSLFSSLVKQFVASFITPLLGTIGATPNFDHLSFTIRR 60

Query: 64 AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL 98
                     YG F+   F F+I A  ++ AI L
Sbjct: 61 H-------AFAYGAFLTEAFSFVIAAIVMYFAIVL 88


>UniRef50_A8N9V8 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
           okayama7#130 RepID=A8N9V8_COPC7
          Length = 209

 Score = 74.1 bits (181), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 28/130 (21%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI------------ 49
            +   F  F +R NV+++AVG+I   AF K+V+SLV++II+PP+ LL             
Sbjct: 34  GLWGGFTAFVLRDNVLEVAVGLIFATAFTKLVTSLVSNIILPPISLLPFMSKNLDEKFLV 93

Query: 50  --GGIDFK--QFAVTLRDAQGDIPAVVMHYG-----------VFIQNVFDFLIVAFAIFM 94
              G +F+      T   A GD  A+V  YG            F      F+ V  A+++
Sbjct: 94  LKKGPNFEPPNGYNTREQASGD-GAIVWAYGVSCERDVVHDRAFADEALKFIGVGAALYL 152

Query: 95  AIKLINKLNR 104
              +     +
Sbjct: 153 IATVYGAFTK 162


>UniRef50_UPI00017434B6 large conductance mechanosensitive channel protein n=1
          Tax=candidate division TM7 single-cell isolate TM7a
          RepID=UPI00017434B6
          Length = 79

 Score = 74.1 bits (181), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)

Query: 3  IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
          + KE R +  R      + G    + FGKIV+SLV DIIMP +G+++G IDF    + + 
Sbjct: 1  MFKELRNYIKRKCDGSCSWGYNW-SRFGKIVTSLVDDIIMPVIGIILGKIDFSNLKLVIT 59

Query: 63 DAQGDIPAVVMH 74
           A G  P   ++
Sbjct: 60 PASGSTPEAAVN 71


>UniRef50_A5KRR6 Large-conductance mechanosensitive channel-like protein n=1
           Tax=candidate division TM7 genomosp. GTL1
           RepID=A5KRR6_9BACT
          Length = 119

 Score = 72.9 bits (178), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 29/85 (34%), Positives = 48/85 (56%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
            +F  F     V  LAVG+++G A   +V SL+ +I+MPPLGL++G  +  +        
Sbjct: 16  SDFMTFIREQGVAGLAVGLVLGGAVTVVVKSLIDNIVMPPLGLVLGSAEGLKGLSLSLGQ 75

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVA 89
                  V+HYGVF+ +V +F+++A
Sbjct: 76  TAAGKDAVLHYGVFLNDVVNFMVIA 100


>UniRef50_A5IYZ8 Large conductance mechanosensitive channel n=1 Tax=Mycoplasma
           agalactiae PG2 RepID=A5IYZ8_MYCAP
          Length = 140

 Score = 72.9 bits (178), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 19/126 (15%)

Query: 11  AMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPA 70
             RGN++ LA+GV+IGA+F  ++SSL  D+IM  +  L               A  ++ A
Sbjct: 13  VKRGNMLLLAIGVLIGASFNAVISSLANDVIMAAIASLFN-----------VQAVSELKA 61

Query: 71  VVMHYGVFIQNVFDFLIVAFAIFMAIKLI--------NKLNRKKEEPAAAPAPTKEEVLL 122
             +  G F+  +  F+IVA  IF+ + L          +  +K        APT +E++L
Sbjct: 62  GPVLIGKFLAALISFIIVALIIFLFLILYFLIKNAVEARKAKKNPPVVVVAAPTTDELIL 121

Query: 123 TEIRDL 128
            E++ L
Sbjct: 122 QELKKL 127


>UniRef50_Q0CER3 Putative uncharacterized protein n=3 Tax=Aspergillus
            RepID=Q0CER3_ASPTN
          Length = 1384

 Score = 71.0 bits (173), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 37/133 (27%)

Query: 4    IKEFREFAMRGNVVDLAVGVI--------------------IGAAFGKIVSSLVADIIMP 43
             + F  FA R NV+++A+G++                    I  AF K+V+S V+DII+P
Sbjct: 1214 WEGFVNFAARDNVLEVALGLMYLPPLPSLPPLPPVPLTQCSIAQAFTKVVTSFVSDIILP 1273

Query: 44   PLGL--------------LIGGIDF--KQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLI 87
             + L              L+ G  +   +   TL  A+ D  A+V+ YGVF++ V  FL 
Sbjct: 1274 IISLLPFLNRNMDQKFAVLMAGPRYVEGEGYNTLTQARDD-GALVLAYGVFLETVLSFLG 1332

Query: 88   VAFAIFMAIKLIN 100
            V+  ++   KL  
Sbjct: 1333 VSVTLYAVAKLYM 1345


>UniRef50_UPI00016B2696 Large-conductance mechanosensitive channel n=1 Tax=candidate
           division TM7 single-cell isolate TM7c
           RepID=UPI00016B2696
          Length = 156

 Score = 69.9 bits (170), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 4/106 (3%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  F +F     V+ LAVG+ IG A G  V  LV   I P +  ++G  +  +      +
Sbjct: 53  LAGFMDFIREQGVIGLAVGLAIGTAAGDTVKKLVEGFISPIVQFIVGSKEGLEAVSLRVE 112

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL--INKLNRKKE 107
             G +      +G F+ +    +  AF I++ I L  +NKL+++K+
Sbjct: 113 MLGRVAE--FKWGAFVSSAITLVATAFVIYLIINLAKLNKLDKEKK 156


>UniRef50_Q2IFL2 Large-conductance mechanosensitive channel-like n=1
           Tax=Anaeromyxobacter dehalogenans 2CP-C
           RepID=Q2IFL2_ANADE
          Length = 137

 Score = 69.5 bits (169), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 32/96 (33%), Positives = 46/96 (47%), Gaps = 11/96 (11%)

Query: 46  GLLIGGIDFKQFAVTLRDAQGDIPAV----------VMHYGVFIQNVFDFLIVAFAIFMA 95
               GG DFK + V LR+    +P            V  YG F+    +FLI+AF +F+ 
Sbjct: 43  AARWGGFDFKDYFVALREIPPGVPRALDAMKKARVPVFAYGSFLTVALNFLILAFIVFLM 102

Query: 96  IKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKE 131
           +K  N+L R +  P     P +  VLL +IRD L+ 
Sbjct: 103 VKQFNRLRRAEPPPPPPAPPEE-VVLLRDIRDALRR 137


>UniRef50_B4WRC7 Large conductance mechanosensitive channel protein n=1
           Tax=Synechococcus sp. PCC 7335 RepID=B4WRC7_9SYNE
          Length = 142

 Score = 67.9 bits (165), Expect = 9e-11,   Method: Composition-based stats.
 Identities = 46/127 (36%), Positives = 69/127 (54%), Gaps = 10/127 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMP-PLGLLIGGIDFKQFAVTL 61
              +F++F +RGNVV+LAV V++GAAF  IV+SLV DII P  L   +        A+  
Sbjct: 17  FANDFKQFLLRGNVVELAVAVVLGAAFNAIVTSLVQDIITPVLLQPALRSAGVDDIAL-- 74

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                 + A  + YGVF+  V +F++V   +F+ ++   + +R  EE A  P PT  E L
Sbjct: 75  ------LSAGGVKYGVFLAAVINFIVVGLVLFLVVRTFARFSRT-EEAAIEPTPTPTEKL 127

Query: 122 LTEIRDL 128
              I+ L
Sbjct: 128 DITIQHL 134


>UniRef50_C9S828 Putative uncharacterized protein n=1 Tax=Verticillium albo-atrum
           VaMs.102 RepID=C9S828_VERA1
          Length = 129

 Score = 65.2 bits (158), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 17/92 (18%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI------------- 49
           +   F +FAM+GN++++A G+I+ AAF  +V+S VA+I+MPPL ++              
Sbjct: 26  LWSGFIDFAMQGNILEIAFGLILAAAFTGLVNSFVANILMPPLSVIFPLNHNMEEKFAVL 85

Query: 50  -GGIDFK--QFAVTLRDAQGDIPAVVMHYGVF 78
             G D+       TL  A+ D  AVV+ YG  
Sbjct: 86  KPGPDYNREDGYTTLARAKDD-GAVVLAYGSV 116


>UniRef50_Q3AHC1 Large-conductive mechanosensitive channel n=1 Tax=Synechococcus sp.
           CC9605 RepID=Q3AHC1_SYNSC
          Length = 109

 Score = 63.3 bits (153), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 8/103 (7%)

Query: 3   IIKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           ++KEF +F   +GNV+ LA+ V++G     I  SL  D++MP +   I    +K  A+  
Sbjct: 4   LLKEFTDFFFTKGNVLALAIAVVVGDQVSAITKSLSTDLLMPLINPFIPHGSYKDLAIPY 63

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
                      +  G  +      ++VA+A+F+ I+   +  R
Sbjct: 64  FGG-------PIAIGKVLDTFVSAMLVAWALFIIIQATKRFER 99


>UniRef50_Q3D697 Large conductance mechanosensitive channel protein n=2
          Tax=Streptococcus agalactiae RepID=Q3D697_STRAG
          Length = 97

 Score = 59.8 bits (144), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 26/65 (40%), Positives = 39/65 (60%), Gaps = 1/65 (1%)

Query: 1  MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPL-GLLIGGIDFKQFAV 59
          + +IKE +EF  +GNV+DLAV VI+GAAF  I++SLV D+I P +   ++        A 
Sbjct: 21 VHMIKELKEFLFKGNVLDLAVAVILGAAFNAIITSLVKDVITPLILNPVLKAAGVSNIAQ 80

Query: 60 TLRDA 64
             + 
Sbjct: 81 LSWNG 85


>UniRef50_C1MQL7 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MQL7_9CHLO
          Length = 218

 Score = 57.5 bits (138), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 20/108 (18%), Positives = 41/108 (37%), Gaps = 7/108 (6%)

Query: 10  FAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIP 69
           F      V +AVG++ G+A  ++V +    ++ P +  + G                 + 
Sbjct: 82  FITSSQAVPVAVGLVFGSALRQLVDAFTTALVAPLVASVGGHSHLVSLRFV-------VH 134

Query: 70  AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTK 117
            +   YGVF+Q V +  +   A+F  + + +   +        P P  
Sbjct: 135 GLAFDYGVFVQAVLETFLTIVALFYLVVVPSSAVKSLRLSPTRPCPEC 182


>UniRef50_Q6SZN0 Putative uncharacterized protein (Fragment) n=1 Tax=Rhodococcus
           fascians RepID=Q6SZN0_RHOFA
          Length = 125

 Score = 57.1 bits (137), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 25/111 (22%), Positives = 49/111 (44%), Gaps = 4/111 (3%)

Query: 21  VGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQ 80
           V +++GAAF  IV++  ++II P +  + G  +        ++     P   ++ G  + 
Sbjct: 3   VAIVVGAAFTAIVTAFTSNIINPLIAAIGGSDELGW----GKEIIAGNPXTFVNIGAVVT 58

Query: 81  NVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKE 131
            +  F+I+A   +  + +     +KK           E  LL +IRD+L  
Sbjct: 59  AIIXFVIIAVVXYFVLIVPANAAKKKFITEPEDKEASETDLLIQIRDILAS 109


>UniRef50_UPI0000D52968 hypothetical protein P700755_20866 n=1 Tax=Psychroflexus torquis
           ATCC 700755 RepID=UPI0000D52968
          Length = 81

 Score = 56.0 bits (134), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 75  YGVFIQNVFDFLIVAFAIFMAIKLINKLNRK---KEEPAAAPAPTKEEVLLTEIRD 127
           +G F+  + ++LI+AF +F+ IK  N        ++        +KE  LL EIRD
Sbjct: 18  FGAFLGEIINYLIIAFVMFLVIKAYNHFEDMVDDEDNEEIVATESKEVTLLKEIRD 73


>UniRef50_Q7NAU3 MscL n=1 Tax=Mycoplasma gallisepticum RepID=Q7NAU3_MYCGA
          Length = 223

 Score = 54.8 bits (131), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 17/120 (14%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K   +   RGN+  LA+G+++G +F  +++SL  D+I+  +  L    D +++ V    
Sbjct: 21  MKNATQVVKRGNIFMLAIGLLLGTSFNAVIASLANDVIIAAIAKLYNVQDLQKWQVQG-- 78

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIV------AFAIFMAIKLINKLNRKKEEPAAAPAPTK 117
                    +  G F   +  F+I+      A  +   I  + K  + K+  A    PT 
Sbjct: 79  ---------IFIGKFFAALLSFVIINVILVSALFVSYYIIEVRKAIKAKQLLAEGVNPTT 129


>UniRef50_A5GSN0 Large-conductance mechanosensitive channel n=1 Tax=Synechococcus
          sp. RCC307 RepID=A5GSN0_SYNR3
          Length = 128

 Score = 53.7 bits (128), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 23/57 (40%), Positives = 32/57 (56%)

Query: 2  SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFA 58
           + +EF +F  RGNVVDLAV VIIGAAF K+V ++V       L   +  +     +
Sbjct: 8  GLGREFLDFINRGNVVDLAVAVIIGAAFTKVVQAVVELFTTAALNPTMAELGIDSIS 64


>UniRef50_B1MYM2 Large-conductance mechanosensitive channel n=1 Tax=Leuconostoc
           citreum KM20 RepID=B1MYM2_LEUCK
          Length = 158

 Score = 53.3 bits (127), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 21/97 (21%), Positives = 42/97 (43%), Gaps = 8/97 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
             +F++F    N++   + V++G +FG  V  LV  +         G + F    +  + 
Sbjct: 23  FGQFKQFLFAPNLLTFVISVVVGNSFGATVKELVNTV--------SGVLAFVHLWLFSKS 74

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN 100
              +   +   +G F  ++   + +AF +F  IK IN
Sbjct: 75  HVMNYTFITKPFGSFFNSLITMIFIAFIVFYTIKFIN 111


>UniRef50_A7HMH6 Putative uncharacterized protein n=1 Tax=Fervidobacterium nodosum
          Rt17-B1 RepID=A7HMH6_FERNB
          Length = 61

 Score = 51.0 bits (121), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 28/44 (63%)

Query: 2  SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPL 45
            +KEF +F  + NV+ LAV +IIG    + V+S V D++MP +
Sbjct: 3  KFMKEFSDFLKQYNVIGLAVAIIIGGKLNQFVTSFVNDLLMPAI 46


>UniRef50_Q0UYA9 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
           RepID=Q0UYA9_PHANO
          Length = 164

 Score = 50.6 bits (120), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 11/98 (11%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
              F  FA+R NV+++AVG+I          +L     +   G    G        T++ 
Sbjct: 60  WDSFSNFALRDNVLEVAVGLI---------RNLDEKFAILKHGPHYNGT-ITNGYNTVKQ 109

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
           A  D  AVV  YG F+  V  F+ +A  +++     ++
Sbjct: 110 ALDD-GAVVFAYGSFLDKVVRFVCIALTLWIIAIAYSR 146


>UniRef50_A7E8P9 Predicted protein n=1 Tax=Sclerotinia sclerotiorum 1980 UF-70
           RepID=A7E8P9_SCLS1
          Length = 231

 Score = 49.1 bits (116), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 26/140 (18%), Positives = 48/140 (34%), Gaps = 49/140 (35%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVS--------------SLVADIIMPPLGL 47
           S    F +FA   NV+ +A+G+II  +F  +++                +   +     +
Sbjct: 30  SFWDGFVDFAFNDNVLHVAIGLIIAQSFTTLITSLVSSVLLPPLSLLPFLNKNLDEKFAV 89

Query: 48  LIGGIDFKQ----------------------------------FAVTLRDAQGDIPAVVM 73
           L  G  +                                       TL+ A  D  A+V+
Sbjct: 90  LRPGPHYGGTLHNHTEIGGGAGEGVEGNSTVVVQMGIEFLYGAGYNTLKQALDD-GAIVL 148

Query: 74  HYGVFIQNVFDFLIVAFAIF 93
            +G F+ NV +F+ V  A++
Sbjct: 149 AWGSFLNNVINFIGVGLALY 168


>UniRef50_C4Z968 Putative uncharacterized protein n=1 Tax=Eubacterium rectale ATCC
           33656 RepID=C4Z968_EUBR3
          Length = 76

 Score = 49.1 bits (116), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 12/41 (29%), Positives = 19/41 (46%)

Query: 78  FIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE 118
           F+  V +FLI+A  +F  +K +N    +          TKE
Sbjct: 25  FLTAVVNFLIMALIVFCIVKAMNAAGERFGHKEEKEPDTKE 65


>UniRef50_C1DYF1 Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1DYF1_9CHLO
          Length = 187

 Score = 46.4 bits (109), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 18/100 (18%), Positives = 42/100 (42%), Gaps = 7/100 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + ++   F +    V +AVG + G+     V + V+  + P +  +      +    T+ 
Sbjct: 51  LFEQLNNFVLSSQAVPVAVGFVFGSCLKNNVDAFVSSFVAPSIAAIGSLQHLRDMHFTVN 110

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL 102
            +       +   GVF++++F+  I   A+F  I +   +
Sbjct: 111 HS-------IFPVGVFVESMFETAITILALFYLIVVPMSM 143


>UniRef50_A7HMH7 Putative uncharacterized protein n=1 Tax=Fervidobacterium nodosum
           Rt17-B1 RepID=A7HMH7_FERNB
          Length = 66

 Score = 44.8 bits (105), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 18/53 (33%), Positives = 28/53 (52%)

Query: 68  IPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
           I    +++G  +    DFLIVAF +F+ IK +NK   K +  A   A   E++
Sbjct: 7   INWHGIYWGKVVSAGIDFLIVAFLVFLLIKSMNKAAEKTKVAAELAAKKVEKI 59


>UniRef50_Q03WP0 Large-conductance mechanosensitive channel n=2 Tax=Leuconostoc
           mesenteroides RepID=Q03WP0_LEUMM
          Length = 158

 Score = 43.3 bits (101), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/134 (20%), Positives = 51/134 (38%), Gaps = 13/134 (9%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           + EFR+F     ++ L++GVI+G +          D+I   +        +    +  ++
Sbjct: 17  VNEFRKFITSPAIIQLSIGVIVGGSLT--------DLIKSVISFASNLFYYLSLLLFSKN 68

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP-----AAAPAPTKE 118
               I  V+       +N      +A  +F  +KL+NK   K+        A      K 
Sbjct: 69  HSAKINLVLDPLRSVFENFLTLCTIAACVFFFVKLVNKFLIKEASETLGYNAQLEETKKL 128

Query: 119 EVLLTEIRDLLKEQ 132
             +  E  +LLK+ 
Sbjct: 129 IKIQHETNELLKKS 142


>UniRef50_Q8PSE0 Large-conductance mechanosensitive channel n=1 Tax=Methanosarcina
          mazei RepID=Q8PSE0_METMA
          Length = 77

 Score = 42.1 bits (98), Expect = 0.005,   Method: Composition-based stats.
 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 7/60 (11%)

Query: 25 IGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFD 84
          +G A    + S V +IIMP +   I G          R A  DI  +V+ +G F+  + +
Sbjct: 1  MGIASTAFIKSFVDNIIMPIITPFIPGG-------AWRTATLDIGPIVLGWGAFLGELIN 53


>UniRef50_Q4A5X4 Putative uncharacterized protein n=2 Tax=Mycoplasma synoviae 53
          RepID=Q4A5X4_MYCS5
          Length = 173

 Score = 41.0 bits (95), Expect = 0.013,   Method: Composition-based stats.
 Identities = 16/84 (19%), Positives = 35/84 (41%), Gaps = 10/84 (11%)

Query: 4  IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           ++ +    R N + LAV  ++GA    ++SS   D+++  +    G  + +++ +    
Sbjct: 11 WQDAKANIKRNNFLLLAVAFLLGAVTNAMISSFANDVVLSYIANAFGIKNLQEWKLENG- 69

Query: 64 AQGDIPAVVMHYGVFIQNVFDFLI 87
                   +  G F+  V  F I
Sbjct: 70 ---------ILIGKFLGTVIQFAI 84


>UniRef50_A4CR84 Protein-export membrane protein n=1 Tax=Synechococcus sp. WH 7805
           RepID=A4CR84_SYNPV
          Length = 100

 Score = 38.7 bits (89), Expect = 0.067,   Method: Composition-based stats.
 Identities = 13/62 (20%), Positives = 25/62 (40%), Gaps = 7/62 (11%)

Query: 43  PPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL 102
             L   + G D+    +             +  G+ +  + + LIV +A+F+ IK+ N  
Sbjct: 24  NTLNSFVRGGDWHNLVILYDGGD-------IAIGIILDVLLNCLIVGWALFIIIKVNNPT 76

Query: 103 NR 104
            R
Sbjct: 77  QR 78


>UniRef50_B0PH06 Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis
           DSM 17241 RepID=B0PH06_9FIRM
          Length = 393

 Score = 38.3 bits (88), Expect = 0.071,   Method: Composition-based stats.
 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 15/111 (13%)

Query: 15  NVVDLA---VGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAV 71
           NVV++A   +  ++  A      + VA ++M  L L+ G I  K        A+ +   +
Sbjct: 34  NVVNMASASIATVVATAMFGASGAAVATVVMTVLVLIFGEILPKTL------AKENSENI 87

Query: 72  VMHYGVFIQNVFDFLI--VAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
            M  G     +  FLI  ++  +F  +K+     R  + PAA P+ T+EE+
Sbjct: 88  AMAAGG----LLSFLIKLLSPIVFFFVKIKELALRLVKGPAAQPSVTEEEL 134


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q48DU1 Large-conductance mechanosensitive channel n=45 ...   149   3e-35
UniRef50_B4S9H4 Large-conductance mechanosensitive channel n=23 ...   145   3e-34
UniRef50_A7GXI2 Large-conductance mechanosensitive channel n=4 T...   142   2e-33
UniRef50_B4RCK7 Large-conductance mechanosensitive channel n=31 ...   141   4e-33
UniRef50_A7I339 Large-conductance mechanosensitive channel n=28 ...   140   9e-33
UniRef50_A4IMP7 Large-conductance mechanosensitive channel n=13 ...   140   2e-32
UniRef50_A6WVY7 Large-conductance mechanosensitive channel n=26 ...   140   2e-32
UniRef50_C4K3W6 Mechanosensitive channel n=1 Tax=Candidatus Hami...   138   6e-32
UniRef50_C7JGJ5 Large-conductance mechanosensitive channel n=9 T...   137   9e-32
UniRef50_Q2JLN5 Large-conductance mechanosensitive channel n=3 T...   137   1e-31
UniRef50_Q2G9Z8 Large-conductance mechanosensitive channel n=3 T...   136   1e-31
UniRef50_B8G6C2 Large-conductance mechanosensitive channel n=7 T...   135   5e-31
UniRef50_C3WUH2 Large-conductance mechanosensitive channel n=5 T...   134   7e-31
UniRef50_D2QT75 Large conductance mechanosensitive channel prote...   134   9e-31
UniRef50_Q1LIC3 Large-conductance mechanosensitive channel n=26 ...   133   2e-30
UniRef50_A1B4B3 Large-conductance mechanosensitive channel n=45 ...   132   3e-30
UniRef50_A4CIE9 Large-conductance mechanosensitive channel n=7 T...   132   3e-30
UniRef50_C3J8B0 Large conductance mechanosensitive channel prote...   132   4e-30
UniRef50_A6L685 Large-conductance mechanosensitive channel n=58 ...   130   1e-29
UniRef50_A2TYX0 Large-conductance mechanosensitive channel n=1 T...   129   3e-29
UniRef50_C6WJF5 Large conductance mechanosensitive channel prote...   129   3e-29
UniRef50_C9LNV3 Large conductance mechanosensitive channel prote...   128   5e-29
UniRef50_A0Q171 Large conductance mechanosensitive channel prote...   128   5e-29
UniRef50_Q3B3W2 Large-conductance mechanosensitive channel n=20 ...   128   5e-29
UniRef50_Q2NQQ0 Large-conductance mechanosensitive channel n=18 ...   128   8e-29
UniRef50_C1XQ99 Large conductance mechanosensitive channel prote...   127   1e-28
UniRef50_C4LHF9 Transport protein of the large conductance mecha...   126   2e-28
UniRef50_C0Z921 Large-conductance mechanosensitive channel n=36 ...   125   4e-28
UniRef50_Q5LGV7 Large-conductance mechanosensitive channel n=20 ...   125   7e-28
UniRef50_Q034S0 Large-conductance mechanosensitive channel n=4 T...   124   9e-28
UniRef50_A3MKN7 Large-conductance mechanosensitive channel n=286...   123   2e-27
UniRef50_Q3ANR9 Large-conductance mechanosensitive channel n=24 ...   123   2e-27
UniRef50_C1RGF4 Large conductance mechanosensitive channel prote...   122   3e-27
UniRef50_Q89ZV7 Large-conductance mechanosensitive channel n=9 T...   121   6e-27
UniRef50_D2LWQ6 Large conductance mechanosensitive channel prote...   120   1e-26
UniRef50_C8NCV5 Large conductance mechanosensitive channel prote...   120   2e-26
UniRef50_A9VKI1 Large-conductance mechanosensitive channel n=72 ...   120   2e-26
UniRef50_Q2JGX8 Large conductance mechanosensitive channel prote...   119   3e-26
UniRef50_B1YKK2 Large-conductance mechanosensitive channel n=2 T...   119   3e-26
UniRef50_C2BQ59 MscL family large conductance mechanosensitive i...   118   4e-26
UniRef50_C0WF41 MscL family large conductance mechanosensitive i...   118   5e-26
UniRef50_A6W442 Large conductance mechanosensitive channel prote...   117   9e-26
UniRef50_D0L6D3 Large conductance mechanosensitive channel prote...   117   9e-26
UniRef50_UPI000050F91C putative large-conductance mechanosensiti...   115   3e-25
UniRef50_A0M1G0 Large-conductance mechanosensitive channel n=10 ...   115   3e-25
UniRef50_C5BZI9 Large conductance mechanosensitive channel prote...   115   4e-25
UniRef50_UPI000196C3D3 hypothetical protein CATMIT_02956 n=1 Tax...   115   4e-25
UniRef50_C6XFL7 Large conductance mechanosensitive channel prote...   114   9e-25
UniRef50_C7MN86 Large conductance mechanosensitive channel prote...   114   9e-25
UniRef50_A4CLF8 Large conductance mechanosensitive channel prote...   114   1e-24
UniRef50_Q5NNP2 Large-conductance mechanosensitive channel n=5 T...   113   1e-24
UniRef50_Q03D91 Large-conductance mechanosensitive channel n=16 ...   113   1e-24
UniRef50_UPI0001C42BC0 large-conductance mechanosensitive channe...   113   1e-24
UniRef50_Q6AGE6 Large-conductance mechanosensitive channel n=7 T...   113   2e-24
UniRef50_D2EUH9 Large conductance mechanosensitive channel prote...   113   2e-24
UniRef50_B2GJ27 Large-conductance mechanosensitive channel n=5 T...   113   2e-24
UniRef50_Q6MD32 Putative mechanosensitive channel of large condu...   113   2e-24
UniRef50_UPI0000DB7E8B PREDICTED: hypothetical protein, partial ...   113   2e-24
UniRef50_C8W9F9 Large conductance mechanosensitive channel prote...   112   3e-24
UniRef50_A9WMF7 Large-conductance mechanosensitive channel n=2 T...   111   5e-24
UniRef50_Q2N8W2 Mechanosensitive channel n=1 Tax=Erythrobacter l...   111   5e-24
UniRef50_B5GFS7 Mechanosensitive channel n=12 Tax=Streptomyces R...   111   6e-24
UniRef50_B0K2H2 Large conductance mechanosensitive channel prote...   111   6e-24
UniRef50_B8DV17 Large conductance mechanosensitive channel prote...   110   1e-23
UniRef50_A6M387 Large-conductance mechanosensitive channel n=7 T...   110   2e-23
UniRef50_D1BCH3 Large conductance mechanosensitive channel prote...   110   2e-23
UniRef50_D2B464 Large conductance mechanosensitive channel prote...   109   2e-23
UniRef50_B9CMP0 Large conductance mechanosensitive channel prote...   108   5e-23
UniRef50_Q82H65 Putative mechanosensitive channel n=2 Tax=Strept...   108   5e-23
UniRef50_C8WNX6 Large conductance mechanosensitive channel prote...   108   5e-23
UniRef50_D1BNK2 Large conductance mechanosensitive channel prote...   108   7e-23
UniRef50_Q9RRR4 Large conductance mechanosensitive channel n=1 T...   108   7e-23
UniRef50_D0WJR5 Large conductance mechanosensitive channel prote...   108   7e-23
UniRef50_Q7UW50 Probable large-conductance mechanosensitive chan...   108   8e-23
UniRef50_B4V9Z0 Mechanosensitive channel n=3 Tax=Streptomyces Re...   107   8e-23
UniRef50_C7MC43 Large conductance mechanosensitive channel prote...   107   9e-23
UniRef50_C4FGI6 Putative uncharacterized protein n=1 Tax=Bifidob...   107   1e-22
UniRef50_Q82ZB4 Large-conductance mechanosensitive channel n=40 ...   107   1e-22
UniRef50_A7B9R5 Putative uncharacterized protein n=1 Tax=Actinom...   106   2e-22
UniRef50_B3DRI7 Large-conductance mechanosensitive channel n=17 ...   106   2e-22
UniRef50_A9KIC1 Large conductance mechanosensitive channel prote...   106   2e-22
UniRef50_A0JZ24 Large conductance mechanosensitive channel prote...   106   3e-22
UniRef50_B8ZU13 Large-conductance mechanosensitive channel n=23 ...   106   3e-22
UniRef50_B4D701 Large conductance mechanosensitive channel prote...   105   4e-22
UniRef50_A9HW97 Large-conductance mechanosensitive channel n=98 ...   105   4e-22
UniRef50_D2R1B6 Large conductance mechanosensitive channel prote...   105   6e-22
UniRef50_A4AI90 Large-conductance mechanosensitive channel n=1 T...   104   7e-22
UniRef50_A8LHK6 Large conductance mechanosensitive channel prote...   103   1e-21
UniRef50_A3CM47 Large conductance mechano-sensitive ion channel,...   103   1e-21
UniRef50_B0T274 Large-conductance mechanosensitive channel n=42 ...   103   1e-21
UniRef50_Q04FK1 Large-conductance mechanosensitive channel n=4 T...   103   2e-21
UniRef50_A7X204 Large-conductance mechanosensitive channel n=51 ...   103   2e-21
UniRef50_C7HUU0 Large conductance mechanosensitive channel prote...   103   2e-21
UniRef50_Q31LP8 Large-conductance mechanosensitive channel n=2 T...   103   2e-21
UniRef50_B0S3E4 Large-conductive mechanosensitive channel n=2 Ta...   103   3e-21
UniRef50_D2MPY5 Large conductance mechanosensitive channel prote...   102   3e-21
UniRef50_A7VB12 Putative uncharacterized protein n=1 Tax=Clostri...   102   3e-21
UniRef50_B5Y8I7 Large conductance mechanosensitive channel prote...   102   4e-21
UniRef50_D1AZE9 Large conductance mechanosensitive channel prote...   101   5e-21
UniRef50_A4F7T6 Large-conductance mechanosensitive channel n=3 T...   101   6e-21
UniRef50_Q8DHB2 Large-conductive mechanosensitive channel n=1 Ta...   101   8e-21
UniRef50_Q5SKL6 Large-conductance mechanosensitive channel n=2 T...   101   8e-21
UniRef50_C5RAB3 MscL family large conductance mechanosensitive i...   101   8e-21
UniRef50_C0QYW6 Large-conductance mechanosensitive channel n=2 T...   100   2e-20
UniRef50_C4FVI2 Putative uncharacterized protein n=1 Tax=Catonel...   100   2e-20
UniRef50_Q9P639 Related to large-conductance mechanosensitive ch...    97   1e-19
UniRef50_B2IVG3 Large conductance mechanosensitive channel prote...    97   1e-19
UniRef50_A1RBS3 Large conductance mechanosensitive channel prote...    96   3e-19
UniRef50_A5UVR8 Large-conductance mechanosensitive channel n=2 T...    96   3e-19
UniRef50_C1AX17 Large-conductance mechanosensitive channel n=2 T...    96   3e-19
UniRef50_C6R3M2 Large conductance mechanosensitive channel prote...    95   5e-19
UniRef50_Q6AAH3 Large conductance mechanosensitive channel n=4 T...    95   5e-19
UniRef50_Q8EW76 Large-conductance mechanosensitive channel n=1 T...    95   5e-19
UniRef50_B1V916 Putative large-conductance mechanosensitive chan...    95   6e-19
UniRef50_P73553 Large-conductance mechanosensitive channel n=2 T...    95   6e-19
UniRef50_Q025U4 Large conductance mechanosensitive channel prote...    95   9e-19
UniRef50_C7H9Q8 Large conductance mechanosensitive channel prote...    95   9e-19
UniRef50_D0P2C5 Large Conductance Mechanosensitive Ion Channel (...    94   1e-18
UniRef50_Q1QDU6 Large-conductance mechanosensitive channel n=5 T...    94   1e-18
UniRef50_B6HL82 Pc21g07880 protein n=6 Tax=Trichocomaceae RepID=...    93   2e-18
UniRef50_B8MJW8 Ion channel, putative n=3 Tax=Trichocomaceae Rep...    93   2e-18
UniRef50_C9RJE4 Large conductance mechanosensitive channel prote...    93   3e-18
UniRef50_A6GYI6 Large-conductance mechanosensitive channel n=4 T...    93   3e-18
UniRef50_Q2NK99 Large-conductance mechanosensitive channel n=2 T...    93   3e-18
UniRef50_A1SES5 Large-conductance mechanosensitive channel n=1 T...    92   5e-18
UniRef50_C7QC56 Large conductance mechanosensitive channel prote...    92   6e-18
UniRef50_UPI0001B45932 large conductance mechanosensitive channe...    92   7e-18
UniRef50_B1XK85 Large conductance mechanosensitive channel prote...    91   1e-17
UniRef50_B8MKR4 Large-conductance mechanosensitive channel, puta...    88   9e-17
UniRef50_Q83MR6 Large-conductance mechanosensitive channel n=2 T...    86   3e-16
UniRef50_Q98B35 Large-conductance mechanosensitive channel n=1 T...    85   8e-16
UniRef50_A4RKI5 Putative uncharacterized protein n=1 Tax=Magnapo...    85   8e-16
UniRef50_Q5HPJ2 Large-conductance mechanosensitive channel n=9 T...    85   8e-16
UniRef50_B3PMZ4 Large-conductance mechanosensitive channel, puta...    83   2e-15
UniRef50_B2VVD2 Putative uncharacterized protein n=1 Tax=Pyrenop...    83   2e-15
UniRef50_D2S4B1 Large conductance mechanosensitive channel prote...    82   5e-15
UniRef50_D2ARQ8 Large conductance mechanosensitive channel prote...    81   9e-15
UniRef50_B3QZY1 Large-conductance mechanosensitive channel n=1 T...    81   1e-14
UniRef50_A5GNA8 Large-conductance mechanosensitive channel n=1 T...    81   1e-14
UniRef50_A8N9V8 Putative uncharacterized protein n=1 Tax=Coprino...    81   1e-14
UniRef50_Q0I7U4 Large-conductive mechanosensitive channel n=2 Ta...    80   3e-14
UniRef50_A7HBZ5 Large conductance mechanosensitive channel prote...    80   3e-14
UniRef50_Q0CER3 Putative uncharacterized protein n=3 Tax=Aspergi...    78   9e-14
UniRef50_D1YYF3 Putative large-conductance mechanosensitive chan...    78   9e-14
UniRef50_Q0IDN4 Large conductance mechanosensitive channel prote...    77   1e-13
UniRef50_A7I494 Large-conductance mechanosensitive channel-like ...    76   3e-13
UniRef50_C7PYG5 Large conductance mechanosensitive channel prote...    76   4e-13
UniRef50_D0P2C6 Large conductance mechanosensitive channel, puta...    76   4e-13
UniRef50_A3Z5P9 Possible large-conductance mechanosensitive chan...    75   6e-13
UniRef50_Q6KH26 Large-conductance mechanosensitive channel n=1 T...    74   2e-12
UniRef50_Q2FQE0 Large conductance mechanosensitive channel prote...    72   4e-12
UniRef50_C1MQL7 Predicted protein n=1 Tax=Micromonas pusilla CCM...    72   5e-12
UniRef50_Q3AHC1 Large-conductive mechanosensitive channel n=1 Ta...    71   1e-11
UniRef50_C5BF23 Putative uncharacterized protein n=1 Tax=Edwards...    71   1e-11
UniRef50_D1J7K2 Large-conductance mechanosensitive channel n=1 T...    70   2e-11
UniRef50_A5IYZ8 Large conductance mechanosensitive channel n=1 T...    69   4e-11
UniRef50_Q0UYA9 Putative uncharacterized protein n=1 Tax=Phaeosp...    69   4e-11
UniRef50_A5Z9U3 Putative uncharacterized protein n=1 Tax=Eubacte...    68   7e-11
UniRef50_A5KRR6 Large-conductance mechanosensitive channel-like ...    68   8e-11
UniRef50_B1MYM2 Large-conductance mechanosensitive channel n=1 T...    66   3e-10
UniRef50_Q6SZN0 Putative uncharacterized protein (Fragment) n=1 ...    66   4e-10
UniRef50_C9S828 Putative uncharacterized protein n=1 Tax=Vertici...    66   4e-10
UniRef50_UPI00017434B6 large conductance mechanosensitive channe...    65   9e-10
UniRef50_C1DYF1 Predicted protein n=1 Tax=Micromonas sp. RCC299 ...    65   1e-09
UniRef50_B4WRC7 Large conductance mechanosensitive channel prote...    64   1e-09
UniRef50_UPI00016B2696 Large-conductance mechanosensitive channe...    63   2e-09
UniRef50_A7E8P9 Predicted protein n=1 Tax=Sclerotinia sclerotior...    61   7e-09
UniRef50_Q3D697 Large conductance mechanosensitive channel prote...    61   9e-09
UniRef50_Q2IFL2 Large-conductance mechanosensitive channel-like ...    60   2e-08
UniRef50_Q7NAU3 MscL n=1 Tax=Mycoplasma gallisepticum RepID=Q7NA...    60   3e-08
UniRef50_A5GSN0 Large-conductance mechanosensitive channel n=1 T...    56   4e-07
UniRef50_A7HMH6 Putative uncharacterized protein n=1 Tax=Fervido...    53   3e-06
UniRef50_UPI0000D52968 hypothetical protein P700755_20866 n=1 Ta...    53   4e-06

Sequences not found previously or not previously below threshold:

UniRef50_Q03WP0 Large-conductance mechanosensitive channel n=2 T...    46   5e-04
UniRef50_A7HMH7 Putative uncharacterized protein n=1 Tax=Fervido...    43   0.003
UniRef50_C4Z968 Putative uncharacterized protein n=1 Tax=Eubacte...    42   0.005
UniRef50_A2C9D0 Possible large-conductance mechanosensitive chan...    39   0.041
UniRef50_Q8PSE0 Large-conductance mechanosensitive channel n=1 T...    38   0.086

>UniRef50_Q48DU1 Large-conductance mechanosensitive channel n=45 Tax=Bacteria
           RepID=MSCL_PSE14
          Length = 148

 Score =  149 bits (376), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 89/137 (64%), Positives = 111/137 (81%), Gaps = 1/137 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS++ EF+ FA++GNVVD+AVG+IIGAAFGKIVSS V D+IMPPLGLLIGG+DF   A+T
Sbjct: 1   MSVLSEFKAFAVKGNVVDMAVGIIIGAAFGKIVSSFVGDVIMPPLGLLIGGVDFSDLAIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA-APAPTKEE 119
           LR AQG  PAV++ YG FIQ V DF+IVAFAIFM +K IN+L R++ +     P P+K+E
Sbjct: 61  LRPAQGTAPAVLLAYGKFIQTVIDFIIVAFAIFMGVKAINRLKREEAKAPTLPPTPSKQE 120

Query: 120 VLLTEIRDLLKEQNNRS 136
           VLL+EIRDLLKEQN  +
Sbjct: 121 VLLSEIRDLLKEQNKPA 137


>UniRef50_B4S9H4 Large-conductance mechanosensitive channel n=23 Tax=Bacteria
           RepID=MSCL_PROA2
          Length = 134

 Score =  145 bits (367), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 80/134 (59%), Positives = 105/134 (78%), Gaps = 1/134 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M  I+EF++FAMRGNVVDLAVG+IIG AFGK+V++LV  ++MPP+GLLIGG++F Q A  
Sbjct: 1   MGFIQEFKDFAMRGNVVDLAVGIIIGGAFGKVVTALVDGVLMPPIGLLIGGVNFDQLAFE 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK-KEEPAAAPAPTKEE 119
           LR A  +  AV ++YG F+Q + DF+I+AF+IF+ IK +N L RK +E P A P P+KEE
Sbjct: 61  LRAATAESAAVSLNYGAFLQTIVDFVIIAFSIFVVIKALNSLKRKSEEAPKAPPVPSKEE 120

Query: 120 VLLTEIRDLLKEQN 133
           VLL EIRDLLKE+ 
Sbjct: 121 VLLGEIRDLLKERG 134


>UniRef50_A7GXI2 Large-conductance mechanosensitive channel n=4 Tax=Bacteria
           RepID=MSCL_CAMC5
          Length = 133

 Score =  142 bits (359), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 79/133 (59%), Positives = 99/133 (74%), Gaps = 2/133 (1%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS I EF+EFAM+GNV+D+AVGV+IG AFGKIVSSLV DIIMP +G++ GG++F    +T
Sbjct: 1   MSFIGEFKEFAMKGNVLDMAVGVVIGTAFGKIVSSLVGDIIMPIVGVITGGVNFTDLKIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA--AAPAPTKE 118
           L+DA   +PAV ++YG FIQ   DFLI+AF IF  IK IN L RK  EP      AP ++
Sbjct: 61  LKDAAQGVPAVTINYGNFIQTAVDFLIIAFCIFCVIKAINSLKRKPAEPEVAQPAAPAED 120

Query: 119 EVLLTEIRDLLKE 131
            VLLT+IRDLLK+
Sbjct: 121 IVLLTQIRDLLKK 133


>UniRef50_B4RCK7 Large-conductance mechanosensitive channel n=31 Tax=Bacteria
           RepID=MSCL_PHEZH
          Length = 139

 Score =  141 bits (357), Expect = 4e-33,   Method: Composition-based stats.
 Identities = 76/139 (54%), Positives = 95/139 (68%), Gaps = 5/139 (3%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSII EFREF  RGNV+DLAVGVIIGAAF  IV +LV +I+MPP+GL++ GIDF   A  
Sbjct: 1   MSIISEFREFIARGNVIDLAVGVIIGAAFNDIVKALVDNIVMPPIGLVLSGIDFSDLAWV 60

Query: 61  LRDAQGDIP---AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE--PAAAPAP 115
           L+      P   AV + YG FI     FLIVA+A+FM +KL+N + R++ E  P   PAP
Sbjct: 61  LKPDDPATPALDAVAIQYGAFINTCIRFLIVAWAVFMLVKLVNVIRRREAEKPPEEKPAP 120

Query: 116 TKEEVLLTEIRDLLKEQNN 134
           T +E LL EIRDLLK + +
Sbjct: 121 TPQETLLMEIRDLLKRRAD 139


>UniRef50_A7I339 Large-conductance mechanosensitive channel n=28 Tax=Bacteria
           RepID=MSCL_CAMHC
          Length = 132

 Score =  140 bits (354), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 77/132 (58%), Positives = 104/132 (78%), Gaps = 1/132 (0%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS IKEF+EFA++GNV+D+AVGV+IG+AFGKIVSSLV D+IMP +G+L GG++F    +T
Sbjct: 1   MSFIKEFKEFAVKGNVIDMAVGVVIGSAFGKIVSSLVGDVIMPVVGVLTGGVNFTDLKIT 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR-KKEEPAAAPAPTKEE 119
           +++A G+  AV ++YG FIQ   DFLI+AF IF+AIK IN+L + +K+EP A   P  E 
Sbjct: 61  IKEAVGENAAVTINYGNFIQVTIDFLIIAFCIFLAIKAINQLKKPEKQEPKAPAEPNDEV 120

Query: 120 VLLTEIRDLLKE 131
            LL+EIRDLLK+
Sbjct: 121 KLLSEIRDLLKK 132


>UniRef50_A4IMP7 Large-conductance mechanosensitive channel n=13 Tax=Bacteria
           RepID=MSCL_GEOTN
          Length = 131

 Score =  140 bits (352), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 79/137 (57%), Positives = 97/137 (70%), Gaps = 11/137 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +  EF++FA+RGNV+DLAVGVIIG AFGKIVSSLV DIIMP +GLL+GGIDF   +  + 
Sbjct: 1   MWNEFKKFAIRGNVIDLAVGVIIGGAFGKIVSSLVNDIIMPLVGLLLGGIDFSNLSWKVG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL----NRKKEEPAAAPAPTKE 118
            A       V+ YG FIQ V DFLI+AF+IF+ +KLINKL     +++E     P  TKE
Sbjct: 61  KA-------VVKYGAFIQTVVDFLIIAFSIFLFVKLINKLYERVKKQEEMEETEPTLTKE 113

Query: 119 EVLLTEIRDLLKEQNNR 135
           E LLTEIRDLLK+Q   
Sbjct: 114 EELLTEIRDLLKQQRET 130


>UniRef50_A6WVY7 Large-conductance mechanosensitive channel n=26 Tax=Bacteria
           RepID=MSCL_OCHA4
          Length = 137

 Score =  140 bits (352), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 64/138 (46%), Positives = 93/138 (67%), Gaps = 7/138 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GN+VDLA+GVIIG AFG +V+S+V DIIMP +GL+ GGIDF    + L 
Sbjct: 1   MLKEFKEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLA 60

Query: 63  D------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT 116
                  A        + YG F+  + +FLI+A+ +F+ +K +N++ +K+E      AP 
Sbjct: 61  GEPRATLAAAREAGATIAYGNFVTLLINFLIIAWVLFLVVKGMNRMKKKEEAKPEPEAP- 119

Query: 117 KEEVLLTEIRDLLKEQNN 134
           +EEVLLTEIRDLL +Q  
Sbjct: 120 REEVLLTEIRDLLAKQKA 137


>UniRef50_C4K3W6 Mechanosensitive channel n=1 Tax=Candidatus Hamiltonella defensa
           5AT (Acyrthosiphon pisum) RepID=C4K3W6_HAMD5
          Length = 150

 Score =  138 bits (347), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 86/150 (57%), Positives = 106/150 (70%), Gaps = 15/150 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS IKEFREFAMRGNV DLA+GVIIG+AFGK+VSSLVADIIMPP+GLLIGG+D KQF+  
Sbjct: 1   MSFIKEFREFAMRGNVADLAIGVIIGSAFGKVVSSLVADIIMPPIGLLIGGVDLKQFSFV 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR---------------K 105
           LR+A+ D+PAV+M+YG F+Q++ D +IV  AIF  IK +NKL R               K
Sbjct: 61  LREARNDVPAVIMNYGSFLQSLVDCIIVTLAIFSVIKFMNKLRRELEGILESRAEINKEK 120

Query: 106 KEEPAAAPAPTKEEVLLTEIRDLLKEQNNR 135
            E       P  +E+LL EIRDLLK+   +
Sbjct: 121 TEVGTQVEPPAPQEILLMEIRDLLKKSTKK 150


>UniRef50_C7JGJ5 Large-conductance mechanosensitive channel n=9 Tax=Acetobacter
           RepID=C7JGJ5_ACEP3
          Length = 159

 Score =  137 bits (346), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 72/141 (51%), Positives = 89/141 (63%), Gaps = 8/141 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             + EFR F MRGNVVDLAVGVIIGAAF  IV+SLV DI  P +GLLIGGIDF    +TL
Sbjct: 12  GWVGEFRAFIMRGNVVDLAVGVIIGAAFTSIVNSLVKDIFNPLIGLLIGGIDFSNLFITL 71

Query: 62  RDA-------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN-RKKEEPAAAP 113
           +              AV ++ G+F+  V  FLIVA AIF  +K + +L+ R+ E+P A P
Sbjct: 72  KGPHLATLEEAQKAGAVTLNVGLFLNAVIQFLIVAMAIFWMVKALTRLHVREDEQPKAPP 131

Query: 114 APTKEEVLLTEIRDLLKEQNN 134
            P+K EVLL +IRD L   N 
Sbjct: 132 PPSKTEVLLEQIRDELAANNK 152


>UniRef50_Q2JLN5 Large-conductance mechanosensitive channel n=3 Tax=Bacteria
           RepID=MSCL_SYNJB
          Length = 132

 Score =  137 bits (345), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 68/133 (51%), Positives = 92/133 (69%), Gaps = 3/133 (2%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + ++EF+ F  RGN +DLAVGV+IG AFGKIV+S VAD+  P LGL+IGG++F+  A  +
Sbjct: 3   AFLEEFKNFISRGNALDLAVGVVIGGAFGKIVTSFVADLFTPVLGLMIGGVNFQHLAWEI 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
             +  D   V ++YG F+Q VFDF+I+AFAIF+ +K IN L RK+EE      P  E VL
Sbjct: 63  GGSPED--PVTINYGSFLQAVFDFVIIAFAIFLLVKAINTLQRKEEESP-PTLPPPEVVL 119

Query: 122 LTEIRDLLKEQNN 134
           LTEIRD+L   + 
Sbjct: 120 LTEIRDILNRHSQ 132


>UniRef50_Q2G9Z8 Large-conductance mechanosensitive channel n=3 Tax=Sphingomonadales
           RepID=MSCL_NOVAD
          Length = 155

 Score =  136 bits (344), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 64/146 (43%), Positives = 87/146 (59%), Gaps = 13/146 (8%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           + ++ EF++F  RGNV+DLAVGVIIG AFGKIV+SL   +IMP +G L GG+DF ++ V 
Sbjct: 10  LGMLGEFKKFIARGNVLDLAVGVIIGGAFGKIVTSLTESVIMPVVGWLTGGVDFTRYFVR 69

Query: 61  LRDAQGDIPA-------------VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
           L     D                 ++ YG FI    +F+IVAF IF+ +K +N++  K E
Sbjct: 70  LGPVPADFKGDPTSYAELKAAGVPMIGYGDFITQAVNFVIVAFIIFLIVKAVNRMFEKPE 129

Query: 108 EPAAAPAPTKEEVLLTEIRDLLKEQN 133
           E  AAP+   E  LL EIRD LK + 
Sbjct: 130 EAPAAPSGPTEVELLAEIRDALKAKG 155


>UniRef50_B8G6C2 Large-conductance mechanosensitive channel n=7 Tax=Bacteria
           RepID=MSCL_CHLAD
          Length = 137

 Score =  135 bits (339), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 67/137 (48%), Positives = 86/137 (62%), Gaps = 7/137 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAVTL 61
           ++ EFR F  RGNV+DLAVGVIIGAAF  I++SLV DII P LGLL+GG  D   + + L
Sbjct: 1   MLNEFRTFINRGNVLDLAVGVIIGAAFTAIINSLVNDIINPLLGLLVGGRTDMSNYFLPL 60

Query: 62  RD------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
                   A+      V+ YG F+  V +FL+VAF IF+ ++  N+ N K  EP A P P
Sbjct: 61  AGQTATTLAEARAAGPVLAYGSFLNAVINFLLVAFVIFLIVRTANRFNPKPAEPPALPQP 120

Query: 116 TKEEVLLTEIRDLLKEQ 132
           T  E LL EIRDLL ++
Sbjct: 121 TPSERLLAEIRDLLAQR 137


>UniRef50_C3WUH2 Large-conductance mechanosensitive channel n=5 Tax=Fusobacterium
           RepID=C3WUH2_9FUSO
          Length = 137

 Score =  134 bits (338), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 71/135 (52%), Positives = 92/135 (68%), Gaps = 1/135 (0%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            +++EF+ F MRGNVVD+AVGVII  AFGKIV+SLV DI MP +G LIG ++F    + L
Sbjct: 3   KLLEEFKAFVMRGNVVDMAVGVIIATAFGKIVASLVNDIFMPIIGALIGNMNFSDLQIKL 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAA-PAPTKEEV 120
                 +    + YG FIQ V +FLI+AF IF+ IK++  L +KKEE  A  P PTKEEV
Sbjct: 63  GTPVEGVEQAAIRYGAFIQEVINFLIIAFCIFVFIKVVTSLQKKKEEKPAPAPEPTKEEV 122

Query: 121 LLTEIRDLLKEQNNR 135
           LLTEIRD L +  ++
Sbjct: 123 LLTEIRDALNKMADK 137


>UniRef50_D2QT75 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=D2QT75_9SPHI
          Length = 163

 Score =  134 bits (337), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 75/141 (53%), Positives = 95/141 (67%), Gaps = 9/141 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFAMRGNV+DLAVGVIIGAAFGKIV S+V D+IMP +G+++G +DF    V L 
Sbjct: 1   MLKEFKEFAMRGNVMDLAVGVIIGAAFGKIVDSVVNDLIMPLVGMVVGNVDFSNLYVPLS 60

Query: 63  D--------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA-AAP 113
           D        A       V  YG F+  V DFLI+AF IF+ I+ +N+L R K +     P
Sbjct: 61  DKITPGLALADARKLGPVFAYGSFLTIVIDFLILAFIIFLLIRGMNRLMRAKADTVDIPP 120

Query: 114 APTKEEVLLTEIRDLLKEQNN 134
           APTKEEVLLTEIRD L   ++
Sbjct: 121 APTKEEVLLTEIRDALVASSS 141


>UniRef50_Q1LIC3 Large-conductance mechanosensitive channel n=26 Tax=Bacteria
           RepID=MSCL_RALME
          Length = 144

 Score =  133 bits (335), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 68/141 (48%), Positives = 88/141 (62%), Gaps = 10/141 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M ++ EF+ FAMRGNV+DLAVGVIIGAAFGKIV S+V D+IMP +G ++G +DF    V 
Sbjct: 1   MGMMSEFKTFAMRGNVIDLAVGVIIGAAFGKIVDSVVNDLIMPVIGRIVGKLDFSNMFVM 60

Query: 61  LRDAQGDIPAV----------VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA 110
           L D     P            V  YG F+  V +F+I+AF IFM ++  NK+  K+ EPA
Sbjct: 61  LADPPPGTPQTLDALKKAGVPVFAYGNFLTIVVNFVILAFIIFMMVRAFNKMREKEAEPA 120

Query: 111 AAPAPTKEEVLLTEIRDLLKE 131
           A     ++ VLL EIRD LK 
Sbjct: 121 APAVTPEDIVLLREIRDSLKA 141


>UniRef50_A1B4B3 Large-conductance mechanosensitive channel n=45 Tax=Bacteria
           RepID=MSCL_PARDP
          Length = 145

 Score =  132 bits (333), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 67/145 (46%), Positives = 90/145 (62%), Gaps = 13/145 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + KEF+EF  RGNV+DLAVG+IIGAAF  IV+SLVAD+I P +GLL GG DF    + L+
Sbjct: 1   MFKEFKEFIARGNVIDLAVGIIIGAAFTAIVNSLVADLINPIIGLLTGGTDFSGHYLVLK 60

Query: 63  DAQG---------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK----LNRKKEEP 109
                        D  A V  YG F+  V +FLI+A+A+F+ +K +N+     +R+KE  
Sbjct: 61  GEVPPGASLQVARDSGASVFAYGAFLSAVINFLIIAWAVFLLVKAVNRVQSAASRQKEAE 120

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQNN 134
           A A A   +E LLTEIRD L+ +  
Sbjct: 121 AEAAAGPTQEELLTEIRDELRARRT 145


>UniRef50_A4CIE9 Large-conductance mechanosensitive channel n=7 Tax=Bacteroidetes
           RepID=A4CIE9_9FLAO
          Length = 136

 Score =  132 bits (333), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 55/136 (40%), Positives = 83/136 (61%), Gaps = 6/136 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F M GNV+DLAV V++ +A G +VS  V DI+MP +G   GG+DF    + L 
Sbjct: 1   MLKEFKKFIMTGNVIDLAVAVLLASAIGLVVSGFVNDIMMPIVGYFTGGVDFSDMKIVLS 60

Query: 63  DAQGDIPAVV------MHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT 116
           +A       V      + YG +I ++ + +IV F +FM +K  NK+ +K+E    AP   
Sbjct: 61  EAVVAADGTVEKPESAVRYGAWINSIINLIIVGFVLFMIVKSYNKVRKKEEPKPEAPKGP 120

Query: 117 KEEVLLTEIRDLLKEQ 132
            +E LL EIRDLLK++
Sbjct: 121 TQEDLLAEIRDLLKKK 136


>UniRef50_C3J8B0 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C3J8B0_9PORP
          Length = 142

 Score =  132 bits (332), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 72/140 (51%), Positives = 94/140 (67%), Gaps = 6/140 (4%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            ++ EF+EFAMRGNV+D+AVG+IIG AFGKIVSSLVAD+IMPP+ LL  G + +     L
Sbjct: 3   KLVSEFKEFAMRGNVMDMAVGIIIGGAFGKIVSSLVADVIMPPITLLTSGSNIEDLKWVL 62

Query: 62  RDAQGDIPAVV-----MHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR-KKEEPAAAPAP 115
           R+A  +   +      M  G F+Q V DF I+AF IFM IK +NKL + K EEPA    P
Sbjct: 63  REAVIEGGEITRPEVAMTVGTFLQAVLDFFIIAFVIFMLIKGMNKLRKAKPEEPATPAEP 122

Query: 116 TKEEVLLTEIRDLLKEQNNR 135
           + E  LL EI++LLK+Q  +
Sbjct: 123 SDEVKLLGEIKELLKKQAEK 142


>UniRef50_A6L685 Large-conductance mechanosensitive channel n=58 Tax=Bacteria
           RepID=MSCL_BACV8
          Length = 146

 Score =  130 bits (327), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 85/141 (60%), Positives = 112/141 (79%), Gaps = 7/141 (4%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S +++F+ FAMRGNV+D+AVGVIIG AFGKIVSS+VAD+IMPP+GLL+GG++F    + L
Sbjct: 5   SFLQDFKAFAMRGNVIDMAVGVIIGGAFGKIVSSIVADVIMPPIGLLVGGVNFTDLKLQL 64

Query: 62  RDAQ----GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP---AAAPA 114
           + A+     +  AV ++YG F+Q  FDF+I+AF+IF+ I+L+ KLNRKKEE    AA PA
Sbjct: 65  KPAEVVDGVEKAAVTLNYGNFLQATFDFIIIAFSIFLFIRLLAKLNRKKEEVPAPAAPPA 124

Query: 115 PTKEEVLLTEIRDLLKEQNNR 135
           P+KEEVLLTEIRDLLKEQ  +
Sbjct: 125 PSKEEVLLTEIRDLLKEQAGK 145


>UniRef50_A2TYX0 Large-conductance mechanosensitive channel n=1 Tax=Polaribacter sp.
           MED152 RepID=A2TYX0_9FLAO
          Length = 138

 Score =  129 bits (324), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 61/139 (43%), Positives = 89/139 (64%), Gaps = 6/139 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV- 59
           M ++KEF++FAM+GN++D+AVG ++GAAF ++V+S    I+ P +GL+    DFK+    
Sbjct: 1   MGMLKEFKDFAMKGNLIDIAVGFVMGAAFKQVVTSFTGGIVSPLIGLIF-EADFKKLKWV 59

Query: 60  ----TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
               TL DA   +  V + YG F+ NV DF+IVAF +FM +K IN   +K+E    AP  
Sbjct: 60  VKEGTLNDAGETVGQVAVLYGDFLTNVIDFIIVAFVMFMIVKGINATKKKEEPKPEAPKG 119

Query: 116 TKEEVLLTEIRDLLKEQNN 134
             +E LL +IRDLL +QN 
Sbjct: 120 PSQEELLEQIRDLLAKQNK 138


>UniRef50_C6WJF5 Large conductance mechanosensitive channel protein n=4
           Tax=Actinomycetales RepID=C6WJF5_ACTMD
          Length = 176

 Score =  129 bits (324), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 53/135 (39%), Positives = 80/135 (59%), Gaps = 6/135 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK F++F MRGNV+DLAV V+IGAAFG IV++   ++I P + L+ G  +   FAV L 
Sbjct: 1   MIKGFKDFLMRGNVIDLAVAVVIGAAFGSIVTAFTNNLINPLVALVGGMENPVGFAVQL- 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEEPAAA-PAPTKEEV 120
              G  P   M +G  +  V +F+I+A  I+    L +NK+  ++E    A P+   +  
Sbjct: 60  ---GASPKTTMDFGALVTAVMNFVIIAAVIYFVFVLPMNKIKERRERGQEAGPSEPTDVE 116

Query: 121 LLTEIRDLLKEQNNR 135
           LL EIRDL+  Q ++
Sbjct: 117 LLKEIRDLMVAQASQ 131


>UniRef50_C9LNV3 Large conductance mechanosensitive channel protein n=1
           Tax=Dialister invisus DSM 15470 RepID=C9LNV3_9FIRM
          Length = 168

 Score =  128 bits (322), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 56/128 (43%), Positives = 84/128 (65%), Gaps = 7/128 (5%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M ++KEFR+FA+RGNVVD+AVGV+IG AFGKI+SSLV +IIMPP+G+++GG+DF    + 
Sbjct: 23  MGMMKEFRDFAVRGNVVDMAVGVVIGGAFGKIISSLVENIIMPPIGMIMGGVDFSNRFIN 82

Query: 61  LRDAQ-------GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
           L            ++   V+ YG F+  + DFLI+AF IF+ ++ +N+   K+E   A  
Sbjct: 83  LGKTPVATLAEAKEMNVPVIAYGQFLNTIIDFLIIAFVIFLVVRQMNRAFPKEEAAPART 142

Query: 114 APTKEEVL 121
               +E +
Sbjct: 143 CQFCKEPI 150


>UniRef50_A0Q171 Large conductance mechanosensitive channel protein n=6
           Tax=Clostridium RepID=A0Q171_CLONN
          Length = 138

 Score =  128 bits (322), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 77/134 (57%), Positives = 100/134 (74%), Gaps = 3/134 (2%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           IKEF+EFAM+GNV+DLAVGV+IG AFGKIVSSLV D+IMP +GL+ GGI+F    +TL+ 
Sbjct: 5   IKEFKEFAMKGNVLDLAVGVVIGGAFGKIVSSLVKDVIMPIIGLITGGINFTYLKITLKH 64

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN---RKKEEPAAAPAPTKEEV 120
             G+ P + ++ G FIQNV DF+I+AF+IFM IKLI+KL     ++E+      P+ E V
Sbjct: 65  GIGNKPPITLNIGNFIQNVVDFIIIAFSIFMFIKLISKLQIKKVEEEKEKEEETPSDEVV 124

Query: 121 LLTEIRDLLKEQNN 134
           LL EIRDLLK+ N 
Sbjct: 125 LLQEIRDLLKKDNK 138


>UniRef50_Q3B3W2 Large-conductance mechanosensitive channel n=20 Tax=Bacteria
           RepID=MSCL_PELLD
          Length = 161

 Score =  128 bits (322), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 58/145 (40%), Positives = 93/145 (64%), Gaps = 15/145 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNVVD+AVG+I+G AFG IV++LV++++MPPLGLL GG+DF    V ++
Sbjct: 1   MLKEFKEFALKGNVVDMAVGIIVGGAFGSIVNTLVSEVMMPPLGLLTGGVDFSNLYVVMK 60

Query: 63  DAQGDIP-----------AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA 111
           +     P           AV ++YG+F+  +  F I+AF++F+ +K IN+L +K +   A
Sbjct: 61  EGVEPGPYAALANARAAGAVTLNYGLFLNALVSFTIMAFSVFILVKAINRLRQKADAAPA 120

Query: 112 APAPTKEEVLLTEIRDLLKEQNNRS 136
            P+       LT    L+ +Q +R 
Sbjct: 121 PPSKKTCPYCLT----LVPQQASRC 141


>UniRef50_Q2NQQ0 Large-conductance mechanosensitive channel n=18
           Tax=Gammaproteobacteria RepID=MSCL_SODGM
          Length = 144

 Score =  128 bits (321), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 78/118 (66%), Positives = 96/118 (81%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS +++FR+FAMRGNVVDLAVG+IIGAAFGKIVSSLVA++IMP LGLLIGGIDFKQF+  
Sbjct: 1   MSFLQKFRKFAMRGNVVDLAVGIIIGAAFGKIVSSLVANVIMPQLGLLIGGIDFKQFSWV 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE 118
           L+ AQGD PAVVM YG+F+QN+FDF+IVAFA+F  IKLIN+   ++         T+ 
Sbjct: 61  LKPAQGDTPAVVMKYGIFLQNIFDFIIVAFAVFCIIKLINRNASQRGGKTRRAVQTEC 118


>UniRef50_C1XQ99 Large conductance mechanosensitive channel protein n=1
           Tax=Meiothermus silvanus DSM 9946 RepID=C1XQ99_9DEIN
          Length = 132

 Score =  127 bits (319), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 56/134 (41%), Positives = 75/134 (55%), Gaps = 8/134 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +++ FR+F +RGNVVDLAV VIIG AFG +V S+V DII P +GL+ G  DF    +   
Sbjct: 1   MLQGFRDFILRGNVVDLAVAVIIGTAFGAVVDSMVKDIITPIIGLIGGQPDFANLRLF-- 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK----LNRKKEEPAAAPAPTKE 118
                     + YG F+  V  F I A  +++ I L  K    + +K + P    AP + 
Sbjct: 59  --ADAKGQGGIAYGSFLNAVISFFIKAAVVYLVIVLPMKRMVEMLKKPQAPEIPAAPPEN 116

Query: 119 EVLLTEIRDLLKEQ 132
            VLL EIRDLLK Q
Sbjct: 117 VVLLREIRDLLKAQ 130


>UniRef50_C4LHF9 Transport protein of the large conductance mechanosensitive ion
           channel family n=4 Tax=Corynebacterineae
           RepID=C4LHF9_CORK4
          Length = 187

 Score =  126 bits (317), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 44/138 (31%), Positives = 69/138 (50%), Gaps = 8/138 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K FR+F MRGNV++LA+ V+IG+AF  IV++    II P +    GG +   +   L 
Sbjct: 1   MLKGFRDFIMRGNVIELAMAVVIGSAFTAIVTAFTKYIINPLIA-CFGGANTDGWGFRLI 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN----KLNRKKEEPAAAPAPTKE 118
                     + +G  +  V +FLI+A  ++  +        ++ +K         P  E
Sbjct: 60  RGNEK---TFLDFGSVLTAVINFLIIAAVVYFILVAPMNKLEEIRKKHMGVKEEEVPVTE 116

Query: 119 EVLLTEIRDLLKEQNNRS 136
           + LL EIRDLL  QN  S
Sbjct: 117 KDLLLEIRDLLAAQNQVS 134


>UniRef50_C0Z921 Large-conductance mechanosensitive channel n=36 Tax=Bacteria
           RepID=MSCL_BREBN
          Length = 154

 Score =  125 bits (314), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 57/131 (43%), Positives = 84/131 (64%), Gaps = 7/131 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNV+DLAVGV+IG AFGKIV+SLV DII P +GLL+G +DF    + L 
Sbjct: 1   MLKEFKEFALKGNVMDLAVGVVIGGAFGKIVTSLVNDIITPLIGLLLGKVDFSGLFINLS 60

Query: 63  D-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
                         A  ++YG+F+ +V DF+I+AF+IF+ IK +N+  RK+E   A    
Sbjct: 61  GVPYKTIAEAKTAHAATLNYGLFLNSVIDFVIIAFSIFIVIKQLNRFKRKQEVEQAPVTT 120

Query: 116 TKEEVLLTEIR 126
            +    ++ I 
Sbjct: 121 KECPHCISAIP 131


>UniRef50_Q5LGV7 Large-conductance mechanosensitive channel n=20 Tax=Bacteria
           RepID=MSCL_BACFN
          Length = 146

 Score =  125 bits (313), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 84/142 (59%), Positives = 106/142 (74%), Gaps = 10/142 (7%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + +++F+ FAM+GNVVD+AVGVIIG AFGKIVSS+VADIIMPPLGLLIGG++F      +
Sbjct: 5   TFLQDFKAFAMKGNVVDMAVGVIIGGAFGKIVSSVVADIIMPPLGLLIGGVNFTDLKWVM 64

Query: 62  R------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK----EEPAA 111
           +      D +    AV ++YG F+Q  FDFLI+AF+IF+ IKLI KL +KK      P A
Sbjct: 65  KAAEYGADGKETAAAVTLNYGNFLQATFDFLIIAFSIFLFIKLITKLTQKKAEAPAAPPA 124

Query: 112 APAPTKEEVLLTEIRDLLKEQN 133
            PAPTKEE+LLTEIRDLLKE+ 
Sbjct: 125 PPAPTKEEILLTEIRDLLKEKQ 146


>UniRef50_Q034S0 Large-conductance mechanosensitive channel n=4 Tax=Lactobacillus
           casei group RepID=MSCL_LACC3
          Length = 123

 Score =  124 bits (311), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 59/132 (44%), Positives = 82/132 (62%), Gaps = 10/132 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F MRGNV+DLAVGVIIG+AF  +V+SL  ++I P L +  G  D      T+ 
Sbjct: 1   MLKEFQKFIMRGNVLDLAVGVIIGSAFTGLVTSLTKNLINPILSMFAGKADLSGLYFTIL 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
            A+         YG FI +V +FLI+AF +F+ +K IN++   K    A PA   +E LL
Sbjct: 61  GAK-------FTYGNFINDVLNFLIIAFVVFLLVKGINRILPSK---PAKPAGPTQEELL 110

Query: 123 TEIRDLLKEQNN 134
           TEIRDLLK+   
Sbjct: 111 TEIRDLLKQDQQ 122


>UniRef50_A3MKN7 Large-conductance mechanosensitive channel n=286 Tax=Bacteria
           RepID=MSCL_BURM7
          Length = 143

 Score =  123 bits (309), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 67/145 (46%), Positives = 90/145 (62%), Gaps = 15/145 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSIIKEF+EFA++GNV+DLA+GVIIG AF KIV S+V D+IMP +G+L GG+DF    V 
Sbjct: 1   MSIIKEFKEFAVKGNVMDLAIGVIIGGAFSKIVDSVVKDLIMPVIGVLTGGLDFSNKFVL 60

Query: 61  LRDAQGDIPA-------------VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
           L                          YG FI  + +F+I+AF IF+ +K INKL + +E
Sbjct: 61  LGQIPASFKGNPESFKDLQAAGVATFGYGSFITVLINFIILAFIIFLMVKFINKLRKPEE 120

Query: 108 EPAAAPAPTKEEVLLTEIRDLLKEQ 132
             AA  A  ++ +LL EIRD LK++
Sbjct: 121 --AAPAATPEDVLLLREIRDSLKQR 143


>UniRef50_Q3ANR9 Large-conductance mechanosensitive channel n=24 Tax=Bacteria
           RepID=MSCL_CHLCH
          Length = 155

 Score =  123 bits (309), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 62/133 (46%), Positives = 91/133 (68%), Gaps = 12/133 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS++KEF+EFA++GNVVD+AVG+IIG AFG IV++LV+ +I+PPLGLLIGG+DF    + 
Sbjct: 1   MSVMKEFKEFAVKGNVVDMAVGIIIGGAFGAIVNNLVSQVILPPLGLLIGGVDFSSLYII 60

Query: 61  LRDA------------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
           L++                  AV ++YGVF+ +VF F+I+AFA+F+ +K IN L R +  
Sbjct: 61  LKEGATQAAPYNSLAEATAAGAVTLNYGVFLNSVFSFVIMAFAVFLLVKSINMLRRTEGS 120

Query: 109 PAAAPAPTKEEVL 121
            +A PAP+  +  
Sbjct: 121 KSAVPAPSTTKEC 133


>UniRef50_C1RGF4 Large conductance mechanosensitive channel protein n=1
           Tax=Cellulomonas flavigena DSM 20109 RepID=C1RGF4_9CELL
          Length = 201

 Score =  122 bits (307), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 44/141 (31%), Positives = 70/141 (49%), Gaps = 6/141 (4%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV-- 59
            + + F++F  RGN ++LAVGV++GAAF  +VS+L    I P +G + G  +        
Sbjct: 30  KVFQGFKDFISRGNAIELAVGVVVGAAFTSVVSALQDAFINPLIGWIFGKPNLDNLWNIG 89

Query: 60  -TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI---NKLNRKKEEPAAAPAP 115
               + +    A  +  GV +  +  FLI A AI+  I L        RK+       AP
Sbjct: 90  PYTWNEEIAAEATPIQVGVILSALLQFLITAAAIYFLIVLPLNALAARRKQGVEEEPAAP 149

Query: 116 TKEEVLLTEIRDLLKEQNNRS 136
            ++ +LL EIRDLL ++   +
Sbjct: 150 AEDILLLQEIRDLLSQRLTPA 170


>UniRef50_Q89ZV7 Large-conductance mechanosensitive channel n=9 Tax=Bacteria
           RepID=MSCL_BACTN
          Length = 148

 Score =  121 bits (305), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 81/144 (56%), Positives = 105/144 (72%), Gaps = 12/144 (8%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + +++F+ FAM+GNV+D+AVGV+IG AFGKIVSSLVA++IMPP+GLL+GG++F      +
Sbjct: 5   TFLQDFKAFAMKGNVIDMAVGVVIGGAFGKIVSSLVANVIMPPIGLLVGGVNFTDLKWVM 64

Query: 62  RDAQGD------IPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK------EEP 109
           + A+         PAV + YG F+Q  FDFLI+AFAIF+ I+LI KL  KK        P
Sbjct: 65  KAAEVGADGKEIAPAVSLDYGQFLQATFDFLIIAFAIFLFIRLITKLTTKKAAEEAPAAP 124

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQN 133
            A PAPTKEEVLLTEIRDLLKE+ 
Sbjct: 125 PAPPAPTKEEVLLTEIRDLLKEKK 148


>UniRef50_D2LWQ6 Large conductance mechanosensitive channel protein n=1 Tax=Bacillus
           cellulosilyticus DSM 2522 RepID=D2LWQ6_BACS4
          Length = 164

 Score =  120 bits (302), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 54/125 (43%), Positives = 76/125 (60%), Gaps = 8/125 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS  + FREFA+RGNVVD+ +GVIIGAAFG IV+S V+D++MPP+GLL+G ++F    + 
Sbjct: 1   MSFFRGFREFAIRGNVVDMGIGVIIGAAFGGIVTSFVSDVLMPPIGLLLGKVNFSNLYIN 60

Query: 61  LRD-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK-EEPAAA 112
           L            +  A  ++YG FI+ V  F+I+AFA ++ I  +NKL R   E     
Sbjct: 61  LSGEHYSSLAEAQEAGAATVNYGAFIETVIHFVIIAFAAYLIIIQMNKLRRVPMESTKQK 120

Query: 113 PAPTK 117
             P  
Sbjct: 121 SCPYC 125


>UniRef50_C8NCV5 Large conductance mechanosensitive channel protein n=1
           Tax=Cardiobacterium hominis ATCC 15826
           RepID=C8NCV5_9GAMM
          Length = 143

 Score =  120 bits (301), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 58/139 (41%), Positives = 80/139 (57%), Gaps = 6/139 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F+ F  RGNVVDLAVGV++GAAFG +VS LV   I P +  L+G  +F     +L 
Sbjct: 1   MLSGFKTFIARGNVVDLAVGVVMGAAFGLVVSGLVESFINPLIAWLVGKPNFDSLMFSLP 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIF-MAIKLINKLN---RKKEEPAAAPAPTKE 118
              G+ P  V  YG  +  + +F +V+ AI+   I  +NKL    +KKEE  A PAP  E
Sbjct: 61  PLIGEEP-TVFQYGKILTAIVNFFLVSLAIYIFIIIPMNKLTASMKKKEEVEAPPAPPSE 119

Query: 119 EV-LLTEIRDLLKEQNNRS 136
           E+ LL EIRD L  +   +
Sbjct: 120 EILLLREIRDSLAVRRAAA 138


>UniRef50_A9VKI1 Large-conductance mechanosensitive channel n=72 Tax=Bacillus
           RepID=MSCL_BACWK
          Length = 133

 Score =  120 bits (300), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 73/136 (53%), Positives = 96/136 (70%), Gaps = 10/136 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +  EF++FA +GNV+DLAVGV+IGAAFGKIVSSLV DII P LG+++GG++F    +T  
Sbjct: 1   MWNEFKKFAFKGNVIDLAVGVVIGAAFGKIVSSLVKDIITPLLGMVLGGVNFTDLKLTFG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK---EEPAAAPAPTKEE 119
            +        + YG FIQ +FDFLI+A AIFM +K+ NKL  K+   E+    P PTKEE
Sbjct: 61  KSS-------IMYGNFIQTIFDFLIIAAAIFMFVKVFNKLTSKREEEEKKEELPEPTKEE 113

Query: 120 VLLTEIRDLLKEQNNR 135
            +L EIRDLLK+QN+ 
Sbjct: 114 EILGEIRDLLKQQNSS 129


>UniRef50_Q2JGX8 Large conductance mechanosensitive channel protein n=3 Tax=Frankia
           RepID=Q2JGX8_FRASC
          Length = 131

 Score =  119 bits (298), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 56/137 (40%), Positives = 70/137 (51%), Gaps = 12/137 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K FR+F MRGNVVDLAV V++G AF  +V+SLV  I  P +  + G  DF     T+  
Sbjct: 1   MKGFRQFLMRGNVVDLAVAVMVGTAFTAVVTSLVKTIFTPLIAAIFGKPDFSALTFTI-- 58

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-----NKLNRKKEEPAAAPAPTKE 118
                   V  YG FI +V  FL VA  I+  + L       +  R +  P   PA T E
Sbjct: 59  -----NGSVFRYGEFINSVIAFLSVATVIYFVVVLPLNTINERRTRGQVPPEEDPALTDE 113

Query: 119 EVLLTEIRDLLKEQNNR 135
             LLTEIRDLL E    
Sbjct: 114 ARLLTEIRDLLAEHRPT 130


>UniRef50_B1YKK2 Large-conductance mechanosensitive channel n=2 Tax=Bacillales
           RepID=MSCL_EXIS2
          Length = 129

 Score =  119 bits (298), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 65/132 (49%), Positives = 86/132 (65%), Gaps = 7/132 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + K F+EFA RGNV+DLAVGVI+GAAF  I+ SLV  I MP +G++IGGID K  +V   
Sbjct: 1   MFKAFKEFAFRGNVIDLAVGVILGAAFSGIIKSLVDSIFMPLIGIIIGGIDVKGLSV--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               ++    + YG F+Q   +F+++AFA+F+ +K IN   RK+E      APT EE LL
Sbjct: 58  ----EVGNANLLYGQFLQASIEFILIAFALFLFVKGINAFRRKEETTEEVAAPTTEEKLL 113

Query: 123 TEIRDLLKEQNN 134
           TEIRD L  Q N
Sbjct: 114 TEIRDALVRQQN 125


>UniRef50_C2BQ59 MscL family large conductance mechanosensitive ion channel n=2
           Tax=Corynebacterium RepID=C2BQ59_9CORY
          Length = 167

 Score =  118 bits (297), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 51/138 (36%), Positives = 71/138 (51%), Gaps = 11/138 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           ++++K F++F MRGNV++LA  VIIG+AF  IV S+   II P +  L            
Sbjct: 3   ITMLKGFKDFIMRGNVIELATAVIIGSAFTAIVKSVTDSIIQPIINSLGSAE-----VGA 57

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRKKEEPAAAPAP 115
           +     D     + +G  I    +FLI+A  ++  I     KL     R+      APAP
Sbjct: 58  VGFHITDAENTFVDFGAVISAAINFLIIAAVVYFLIVMPINKLTEAAKRRHGVDPEAPAP 117

Query: 116 TKEEVLLTEIRDLLKEQN 133
           T EE LL EIRDLL+ QN
Sbjct: 118 TSEE-LLAEIRDLLEAQN 134


>UniRef50_C0WF41 MscL family large conductance mechanosensitive ion channel n=2
           Tax=Corynebacterium RepID=C0WF41_9CORY
          Length = 165

 Score =  118 bits (296), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 53/139 (38%), Positives = 76/139 (54%), Gaps = 11/139 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F MRGNVV+LA  VIIG+AF  IV+S+   II P +    G  +         
Sbjct: 1   MLKGFKDFIMRGNVVELATAVIIGSAFTAIVTSVTDSIIQPIINS-FGSAEVDGLGF--- 56

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-NKL----NRKKEEPAAAPAPTK 117
               D  + ++ +G  I    +FLI+A  ++  I +  NKL     R++     APAPT 
Sbjct: 57  -QITDNKSTLVDFGAVITAAINFLIIAAVVYFLIVMPLNKLTEASKRRQGVDPEAPAPTS 115

Query: 118 EEVLLTEIRDLLKEQNNRS 136
           EE LL EIRDLL+ QN  +
Sbjct: 116 EE-LLAEIRDLLQAQNADA 133


>UniRef50_A6W442 Large conductance mechanosensitive channel protein n=2
           Tax=Actinomycetales RepID=A6W442_KINRD
          Length = 151

 Score =  117 bits (294), Expect = 9e-26,   Method: Composition-based stats.
 Identities = 55/141 (39%), Positives = 81/141 (57%), Gaps = 7/141 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV- 59
           M +I+ F++F +RGNV+DLAV V+IGAAF  +V+SLV  +I P +  + G  +     V 
Sbjct: 1   MKLIEGFKDFVLRGNVIDLAVAVVIGAAFTGVVTSLVQGLIDPIIAAVGGSANLDGAWVV 60

Query: 60  ---TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKL--NRKKEEPAAAP 113
              TL +       V +  G  +  V +F+IVA  ++   +  +N+L   RKK E AA  
Sbjct: 61  PLRTLHEGTPQEEVVGIQVGTVVSAVVNFVIVAAVVYFGILTPVNRLLALRKKGEVAAPA 120

Query: 114 APTKEEVLLTEIRDLLKEQNN 134
           AP ++ +LLTEIRDLL  Q  
Sbjct: 121 APAEDVLLLTEIRDLLARQAG 141


>UniRef50_D0L6D3 Large conductance mechanosensitive channel protein n=8
           Tax=Actinomycetales RepID=D0L6D3_GORB4
          Length = 274

 Score =  117 bits (294), Expect = 9e-26,   Method: Composition-based stats.
 Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 6/135 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K FREF ++GNVV+LA  VI+G AF  IV++    I+ P +  +  G D  +    L 
Sbjct: 1   MLKGFREFILKGNVVELATAVIVGTAFTAIVTAFTTGIVEPIINSIPVGTDAAKG---LG 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK-LINKLNRKKEEPAAAPAPTKEEVL 121
               D  +  +  G  I    +F+I+A  ++  I    NKL         +     E  L
Sbjct: 58  FQITDKASTYVDIGAVITAFINFIIIAAVVYFLIIMPYNKLAELGGFGKKSEV--TEVAL 115

Query: 122 LTEIRDLLKEQNNRS 136
           LTEIRDLL  + + +
Sbjct: 116 LTEIRDLLDPEGSSA 130


>UniRef50_UPI000050F91C putative large-conductance mechanosensitive channel protein n=1
           Tax=Brevibacterium linens BL2 RepID=UPI000050F91C
          Length = 158

 Score =  115 bits (289), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 44/136 (32%), Positives = 69/136 (50%), Gaps = 6/136 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K FR+F ++GNVV+LA  VIIG AF  IV++    II P +  + G     +      
Sbjct: 1   MLKGFRDFILQGNVVELATAVIIGGAFTAIVTAFSDKIINPLIAAVGGA----EGPALSF 56

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKLNR-KKEEPAAAPAPTKEEV 120
             + ++P   +  G  I    +FLIVA  ++   I  +NKLN  +K        P   E 
Sbjct: 57  QIKENVPETTIDLGAVITAAINFLIVAAIVYFIIIVPMNKLNELRKRGAPEEEVPPTTED 116

Query: 121 LLTEIRDLLKEQNNRS 136
           LL +IR++L+ Q   +
Sbjct: 117 LLGDIREILRTQAATT 132


>UniRef50_A0M1G0 Large-conductance mechanosensitive channel n=10 Tax=Bacteroidetes
           RepID=A0M1G0_GRAFK
          Length = 148

 Score =  115 bits (289), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 55/141 (39%), Positives = 84/141 (59%), Gaps = 7/141 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M I KEF+EFA++GN++D+AVG+IIG AF K+V  LV  IIMPPL +L  GI +      
Sbjct: 1   MGIFKEFKEFAVKGNMIDMAVGIIIGTAFNKVVDVLVKQIIMPPLSMLTDGISYANRKFV 60

Query: 61  LRDAQGDIPAVV------MHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA-AAP 113
           LRD  G    V       + YG+ I+ + DF+++ F +F+ +K +N+   K ++P     
Sbjct: 61  LRDGIGAEGDVNYIEEISIGYGLLIETLIDFIVIGFVVFLVVKFMNRFRNKAQDPKNTEV 120

Query: 114 APTKEEVLLTEIRDLLKEQNN 134
              K+  LL+ + D ++EQN 
Sbjct: 121 VTPKDIELLSSLNDKMEEQNK 141


>UniRef50_C5BZI9 Large conductance mechanosensitive channel protein n=1
           Tax=Beutenbergia cavernae DSM 12333 RepID=C5BZI9_BEUC1
          Length = 166

 Score =  115 bits (289), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 42/136 (30%), Positives = 71/136 (52%), Gaps = 6/136 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQ---FAV 59
           ++  F+EF  RGN V+LAVG++IGAAF  +++++V  ++ P +G + G  +      + +
Sbjct: 1   MLSGFKEFIARGNAVELAVGIVIGAAFTAVITAVVEGVLNPLIGGIFGQPNLDNIWVWTL 60

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL---NRKKEEPAAAPAPT 116
              D    IP   M  G+ +  + +F++VA AI+  +          R   +      P 
Sbjct: 61  NEGDPAAGIPPSEMKVGMVLTALVNFVLVAAAIYFLVVAPLNALARRRATGQEPEPAIPA 120

Query: 117 KEEVLLTEIRDLLKEQ 132
           ++  LLTEIRDLL  Q
Sbjct: 121 EDIQLLTEIRDLLARQ 136


>UniRef50_UPI000196C3D3 hypothetical protein CATMIT_02956 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196C3D3
          Length = 130

 Score =  115 bits (289), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 58/134 (43%), Positives = 83/134 (61%), Gaps = 8/134 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            +  EF+EFA +GNV+D+AVGVI+G A   +V+SLV DIIMP L  +I      +    +
Sbjct: 3   KLWNEFKEFAFKGNVIDMAVGVILGTAITAVVTSLVQDIIMPVLSAII------KIPSDI 56

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN--RKKEEPAAAPAPTKEE 119
            +    +  + + YG F+ N+ +FL++AF IF+ IK INK+   RKKEE A      ++ 
Sbjct: 57  TELTLKVNNINIKYGSFLSNLINFLLMAFCIFICIKAINKVMSFRKKEEEAVPAPKPEDI 116

Query: 120 VLLTEIRDLLKEQN 133
            LL EIRDLLKE+ 
Sbjct: 117 ALLEEIRDLLKEKK 130


>UniRef50_C6XFL7 Large conductance mechanosensitive channel protein n=1
           Tax=Candidatus Liberibacter asiaticus str. psy62
           RepID=C6XFL7_LIBAP
          Length = 141

 Score =  114 bits (286), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 54/138 (39%), Positives = 82/138 (59%), Gaps = 11/138 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG-GIDFKQFAVTL 61
           +  EF++F  RGNV+DL+VG+IIG AF ++V S+V DI+MP +G ++G G DF  + + L
Sbjct: 7   VFNEFKKFIARGNVIDLSVGIIIGGAFNRVVQSIVEDIMMPLVGCVMGNGTDFSNYFLPL 66

Query: 62  RD-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPA 114
                    ++      V  YG F   + +F I+A  +F+ I+ +NKL ++ E     PA
Sbjct: 67  SSEIKSSLISEARKQGAVFAYGSFASVLVNFFILAGVVFVLIQFMNKLVKQTENVKNPPA 126

Query: 115 PTKEEVLLTEIRDLLKEQ 132
              E  LLTEIRDLL++ 
Sbjct: 127 ---EVQLLTEIRDLLQKN 141


>UniRef50_C7MN86 Large conductance mechanosensitive channel protein n=9 Tax=Bacteria
           RepID=C7MN86_CRYCD
          Length = 146

 Score =  114 bits (285), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 53/128 (41%), Positives = 75/128 (58%), Gaps = 7/128 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             +KEF+EF  RGNV+D+AVG+IIGAAF  IV+SLV+D++MP + L IGG DF   AVT 
Sbjct: 3   GFLKEFKEFVSRGNVMDMAVGIIIGAAFTAIVTSLVSDVVMPIVSLAIGGADFSSLAVTF 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN----KLNRKKEEPAAAPAPTK 117
                   A  ++YG FIQ + +F++VAF +F  +K I      +   K++     A  +
Sbjct: 63  GTGD---NAATLNYGKFIQAIVNFILVAFVVFCLVKAIATTEGHIASAKKDSQEESAVRE 119

Query: 118 EEVLLTEI 125
                 EI
Sbjct: 120 CPFCKEEI 127


>UniRef50_A4CLF8 Large conductance mechanosensitive channel protein n=1
           Tax=Robiginitalea biformata HTCC2501 RepID=A4CLF8_9FLAO
          Length = 144

 Score =  114 bits (285), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 50/134 (37%), Positives = 79/134 (58%), Gaps = 1/134 (0%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             I+EF+ FA++GN+ D+A+G+IIG AF  +V++LV +I+ PPL      + F      +
Sbjct: 3   GFIREFKNFAIKGNMFDMAIGIIIGTAFNNVVNALVKEILTPPLAFFTSEVQFTNMRWVI 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA-AAPAPTKEEV 120
           R+A      + M YG+ ++ + DF I+A  IF+ IK +N++  + E+PA  A    KE  
Sbjct: 63  REATDTQEEITMGYGILLEALIDFGIIALTIFLLIKALNRIRSRAEDPADKAEVTPKEIE 122

Query: 121 LLTEIRDLLKEQNN 134
           LL  I  L+ EQN 
Sbjct: 123 LLARIEGLMHEQNQ 136


>UniRef50_Q5NNP2 Large-conductance mechanosensitive channel n=5
           Tax=Sphingomonadaceae RepID=MSCL_ZYMMO
          Length = 154

 Score =  113 bits (284), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 60/154 (38%), Positives = 84/154 (54%), Gaps = 21/154 (13%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSI+ +F+ F  +GNV+ L + VI+G AF KI+SS+  D++MP +G + GG+DF  F + 
Sbjct: 1   MSILTDFKNFISKGNVLGLGIAVIMGDAFNKIISSVTGDLLMPIIGAVFGGVDFSGFFIR 60

Query: 61  LRDAQGDIPA-------------VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR--- 104
           L                       +  YG F+  V +F+IVAF +FM +KL  KL +   
Sbjct: 61  LGAVPAGYTGSLTSYNDLKKAGVPLFGYGQFLTVVVNFVIVAFILFMIMKLAAKLQKELD 120

Query: 105 ----KKEEPAAAPAPTKE-EVLLTEIRDLLKEQN 133
               KKEE  A  APT E  VLL EIRD L+ + 
Sbjct: 121 KTEAKKEEKIAEAAPTPEDIVLLREIRDELRGKK 154


>UniRef50_Q03D91 Large-conductance mechanosensitive channel n=16 Tax=Bacteria
           RepID=MSCL_PEDPA
          Length = 140

 Score =  113 bits (284), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 62/129 (48%), Positives = 79/129 (61%), Gaps = 9/129 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EF  RGNV+DLAVGVIIG AF  IV SLV  +I P +GL IGGIDF  + +   
Sbjct: 1   MLKEFKEFVSRGNVLDLAVGVIIGGAFTSIVKSLVNYLINPLIGLFIGGIDFSDWVL--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE--EV 120
                +      +G FI  V +FLI+AF +F+ +KL+NK   KKEE     A   E  E+
Sbjct: 58  ----KVAGATFKFGSFINAVINFLIIAFVVFILVKLVNKFLPKKEEQEDDEAEAIENSEI 113

Query: 121 LLTEIRDLL 129
            L EIRD L
Sbjct: 114 YLKEIRDAL 122


>UniRef50_UPI0001C42BC0 large-conductance mechanosensitive channel n=1 Tax=Bacillus
           pseudofirmus OF4 RepID=UPI0001C42BC0
          Length = 178

 Score =  113 bits (284), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 48/116 (41%), Positives = 73/116 (62%), Gaps = 7/116 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M+I+ EF+EFA+RGNV+D++VGVIIG  F KIV S V D+IMPP  +L G +DF    + 
Sbjct: 1   MNILHEFKEFAVRGNVIDMSVGVIIGTTFAKIVESFVEDVIMPPFSVLFGQVDFSNLYLN 60

Query: 61  LRD-------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP 109
           L D               ++ YG+F+ ++  F IVAF +F+ ++ +N++ R  E+P
Sbjct: 61  LSDRRFNSFAEAEAAGIPMLKYGMFLNHIVHFAIVAFILFLFVRQMNRIRRPDEDP 116


>UniRef50_Q6AGE6 Large-conductance mechanosensitive channel n=7 Tax=Actinomycetales
           RepID=Q6AGE6_LEIXX
          Length = 145

 Score =  113 bits (283), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 47/139 (33%), Positives = 75/139 (53%), Gaps = 12/139 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++ EF+EF +RGNV+DLAV V+IGAAF  IV+++V ++I P +G         +  +   
Sbjct: 1   MLSEFKEFILRGNVIDLAVAVVIGAAFTTIVTAIVTNLINPLIGAFFQANALDETMIV-- 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-NKLNRKKEE-----PAAAPAPT 116
                +    + +G  +  +  FLI+A  ++ A     NKL  ++E           AP 
Sbjct: 59  ----SLNGSDIRFGAVLGAIVTFLIIAIVVYFAFVFPLNKLKERQERLRSKGVVEPGAPV 114

Query: 117 KEEVLLTEIRDLLKEQNNR 135
            E  +LTEIRDLLK+Q ++
Sbjct: 115 TELDVLTEIRDLLKKQQSQ 133


>UniRef50_D2EUH9 Large conductance mechanosensitive channel protein n=8
           Tax=Bacteroidales RepID=D2EUH9_9BACE
          Length = 144

 Score =  113 bits (283), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 82/140 (58%), Positives = 105/140 (75%), Gaps = 9/140 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S ++EF+ FAM+GNV+D+AVGVIIG AFGKIVSS+VAD+IMPP+GLL+GG++F      L
Sbjct: 5   SFLQEFKAFAMKGNVIDMAVGVIIGGAFGKIVSSIVADVIMPPIGLLVGGVNFTDLKWVL 64

Query: 62  RDAQG----DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN-----RKKEEPAAA 112
           + A+     +I AV ++YG F+Q  FDFLI+AF+IFM IKL+ KL           P A 
Sbjct: 65  KPAEMVDGKEIAAVTLNYGNFLQVTFDFLIIAFSIFMFIKLLTKLTEKKKEEAPAAPPAP 124

Query: 113 PAPTKEEVLLTEIRDLLKEQ 132
           PAP+KEEVLLTEIRDLLKE+
Sbjct: 125 PAPSKEEVLLTEIRDLLKEK 144


>UniRef50_B2GJ27 Large-conductance mechanosensitive channel n=5 Tax=Actinomycetales
           RepID=B2GJ27_KOCRD
          Length = 144

 Score =  113 bits (283), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 52/133 (39%), Positives = 76/133 (57%), Gaps = 11/133 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F+EF M+GNV+DLAV VIIGAAF KIV++LV  ++MP +  ++G  +F  FAV   
Sbjct: 1   MLSGFKEFIMKGNVMDLAVAVIIGAAFSKIVNALVESVLMPAISAVVGSPNFDTFAVVTL 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI-----KLINKLNRKKEEPAAAPAPTK 117
                     + +GV +  V +FL++A A++  I     K+I + NR+      A     
Sbjct: 61  RGNE------LKFGVLLTAVVNFLLIAAAVYFCIVLPMNKMIERRNRRMGIEPTAEPADP 114

Query: 118 EEVLLTEIRDLLK 130
             VLLTEIRD L 
Sbjct: 115 NTVLLTEIRDALA 127


>UniRef50_Q6MD32 Putative mechanosensitive channel of large conductance n=1
           Tax=Candidatus Protochlamydia amoebophila UWE25
           RepID=Q6MD32_PARUW
          Length = 133

 Score =  113 bits (283), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 52/126 (41%), Positives = 78/126 (61%), Gaps = 3/126 (2%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M+ +KEF+EFA+RGN VDLA+G+IIG  F K V+SLV D+IMP +GLL+GG DF   ++ 
Sbjct: 1   MTWLKEFKEFALRGNRVDLAIGIIIGGVFSKAVNSLVTDVIMPLIGLLLGGADFSALSLK 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
           L   +     V + YG+F+  + D LI++  IF+ IK +N+L  K+ + +      +   
Sbjct: 61  LHLPESAAAPVAVKYGIFVNTLVDLLILSSVIFIVIKGMNRLYEKRSKAS---CTRECPE 117

Query: 121 LLTEIR 126
            L  I 
Sbjct: 118 CLMTIP 123


>UniRef50_UPI0000DB7E8B PREDICTED: hypothetical protein, partial n=1 Tax=Apis mellifera
           RepID=UPI0000DB7E8B
          Length = 141

 Score =  113 bits (282), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 55/138 (39%), Positives = 81/138 (58%), Gaps = 15/138 (10%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M  I++F+ F +RGNV+DLAVG+++G AF  +V SLV ++IMPP+GLLIGG+DF    +T
Sbjct: 5   MKFIEQFKAFLLRGNVIDLAVGMVVGTAFTNMVKSLVDNVIMPPIGLLIGGVDFSNLFIT 64

Query: 61  LR------------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
           LR             A     AV ++ G+FI  V   +I+ FAIF+ +K I+KL++    
Sbjct: 65  LRSGSKYPGPYETLGAAQAAGAVTLNIGLFINTVISLVIIGFAIFLVVKGIDKLHKS--- 121

Query: 109 PAAAPAPTKEEVLLTEIR 126
           PA      +     T+I 
Sbjct: 122 PAPKATTKQCPQCCTDIP 139


>UniRef50_C8W9F9 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C8W9F9_ATOPD
          Length = 149

 Score =  112 bits (281), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 47/133 (35%), Positives = 74/133 (55%), Gaps = 12/133 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL-IGGIDFKQFAVT 60
             ++EF+EF  +GNV+D+A+G+IIG AF  IV+SLV DII P + L+  GG +    ++ 
Sbjct: 3   KFLEEFKEFIQQGNVMDMAIGIIIGGAFTAIVTSLVNDIINPFIKLISGGGTEVSGLSIP 62

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN------KLNRKKEEPAAAPA 114
           +   Q       + +G FI  + +FLI+AF +F  +K +N      KL + KEE     A
Sbjct: 63  VPGTQNG-----IDFGAFISAIINFLIIAFIVFCMVKALNKFMKASKLEKDKEEAVEEVA 117

Query: 115 PTKEEVLLTEIRD 127
                  L E+++
Sbjct: 118 APHCPHCLEEVKE 130


>UniRef50_A9WMF7 Large-conductance mechanosensitive channel n=2 Tax=Micrococcineae
           RepID=MSCL_RENSM
          Length = 133

 Score =  111 bits (279), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 54/136 (39%), Positives = 78/136 (57%), Gaps = 8/136 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK FR+F ++GNVVDLAV V+IGAAFG +V++LV +IIMP +  ++G   F        
Sbjct: 1   MIKGFRDFILKGNVVDLAVAVVIGAAFGTVVTTLVNNIIMPLIAGIVGKPSFND---VWA 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN-----KLNRKKEEPAAAPAPTK 117
              G  PA  +  G FI  + +F+I+A AI+  + +       + N K    A    P  
Sbjct: 58  FQIGSDPANKLLLGAFITVLLNFVIIAAAIYFMVVVPMNHVIARRNAKLGIKAGEETPDP 117

Query: 118 EEVLLTEIRDLLKEQN 133
           + VLLTEIRD LK ++
Sbjct: 118 QIVLLTEIRDALKSRS 133


>UniRef50_Q2N8W2 Mechanosensitive channel n=1 Tax=Erythrobacter litoralis HTCC2594
           RepID=Q2N8W2_ERYLH
          Length = 169

 Score =  111 bits (279), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 51/157 (32%), Positives = 79/157 (50%), Gaps = 22/157 (14%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MS+  EF++F  RGNVVDLAVGV+IGAAF  IV+ L   I+MP +G + G IDF  + + 
Sbjct: 1   MSLGTEFKKFIARGNVVDLAVGVVIGAAFSGIVTQLTEAILMPLIGWIFGDIDFSNWFLR 60

Query: 61  LRDAQGDIPA-------------VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
           L +                     ++ YG  I  + +FLIVAFA+FM ++ +NK++ + +
Sbjct: 61  LGEIPEGYEGALDNYEQLKEAGVAMIGYGALITALINFLIVAFALFMLVRSVNKVSDEIK 120

Query: 108 EPAAAPAPT---------KEEVLLTEIRDLLKEQNNR 135
              A    +          +  +L +I   L+     
Sbjct: 121 ARQAETEDSSKSDDVPTDPQLDVLKKILAELRSDGAS 157


>UniRef50_B5GFS7 Mechanosensitive channel n=12 Tax=Streptomyces RepID=B5GFS7_9ACTO
          Length = 194

 Score =  111 bits (278), Expect = 6e-24,   Method: Composition-based stats.
 Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 13/142 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            + + F+ F MRGNV+DLAV V+IGAAF  IV+++V  +I P +G   G  D  Q++  L
Sbjct: 8   GVWEGFKSFLMRGNVIDLAVAVVIGAAFTNIVNAVVKGVINPVVGA-FGTQDLDQYSYCL 66

Query: 62  ------RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK------LNRKKEEP 109
                      +   + + +G  +     FLI A  ++  + L           R++ + 
Sbjct: 67  ESPCVPAHGGEEAQGIQIMWGTVLSAALTFLITAAVVYFLMVLPMSRYLARLAARREAKY 126

Query: 110 AAAPAPTKEEVLLTEIRDLLKE 131
                P  E  +L +IRD L  
Sbjct: 127 GTPEVPVSELDVLKDIRDELVA 148


>UniRef50_B0K2H2 Large conductance mechanosensitive channel protein n=11
           Tax=Bacteria RepID=B0K2H2_THEPX
          Length = 126

 Score =  111 bits (278), Expect = 6e-24,   Method: Composition-based stats.
 Identities = 53/137 (38%), Positives = 77/137 (56%), Gaps = 18/137 (13%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F+EF MRGNV+DLAV VIIG AF KIV+SLV D++ P +G + G  DF        
Sbjct: 1   MLKGFKEFIMRGNVLDLAVAVIIGGAFNKIVNSLVVDVLTPLIGAIFGAPDFSAIKF--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE-------PAAAPAP 115
                     +  G FI  V +F+++A AI+  +       + ++E       P A+P P
Sbjct: 58  --------GPISIGNFINAVINFIVIAAAIYFFVVAPINTIKNRKEKQKQQQTPQASPEP 109

Query: 116 TKEEVLLTEIRDLLKEQ 132
           ++E  LL EI D+LKE+
Sbjct: 110 SEEVKLLREILDMLKEK 126


>UniRef50_B8DV17 Large conductance mechanosensitive channel protein n=4
           Tax=Bifidobacterium animalis subsp. lactis
           RepID=B8DV17_BIFA0
          Length = 166

 Score =  110 bits (276), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 17/148 (11%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +I  F++F  RGN+VD+AVGV++GAA   +V+S+V  II P +  + G  D  +      
Sbjct: 1   MIDGFKKFIARGNMVDMAVGVVMGAAVTAVVNSVVDGIINPLVAAIFGKPDLSK-TWNWT 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKLNRKKEE------------P 109
                    V+ +G  +  + +FL++A A++   +  IN L    E+             
Sbjct: 60  ITNWAGENSVISFGSVLNALLNFLLIALAVYFCIVVPINNLRDMTEKAMAKVKGDDSDVA 119

Query: 110 AAAPAPTKEEV---LLTEIRDLLKEQNN 134
           A  P  + EE    LL +IR+ L  Q  
Sbjct: 120 AEEPDLSPEEQTVILLQDIRNALAAQQP 147


>UniRef50_A6M387 Large-conductance mechanosensitive channel n=7 Tax=cellular
           organisms RepID=MSCL_CLOB8
          Length = 146

 Score =  110 bits (275), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 64/131 (48%), Positives = 84/131 (64%), Gaps = 8/131 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + KEF+EFAM+GN+V LA+GV+IG AF KIV+SLV DIIMP +GLL+G +DF     TL 
Sbjct: 1   MFKEFKEFAMKGNMVSLAIGVVIGGAFSKIVTSLVNDIIMPLVGLLMGRVDFSNLFFTLG 60

Query: 63  DA-------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
                      D     ++YG+FI N+ DFLIVAF+IF+ I+ I+KL +KK E    P  
Sbjct: 61  SGNFKTVQEAKDAGVATVNYGIFINNIIDFLIVAFSIFIIIQQISKLTKKKGE-NIVPDK 119

Query: 116 TKEEVLLTEIR 126
            K +   TEI 
Sbjct: 120 KKCKYCYTEIN 130


>UniRef50_D1BCH3 Large conductance mechanosensitive channel protein n=1
           Tax=Sanguibacter keddieii DSM 10542 RepID=D1BCH3_SANKS
          Length = 164

 Score =  110 bits (275), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 46/136 (33%), Positives = 70/136 (51%), Gaps = 9/136 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           +++  F+EF MRGN +DLAVGVIIGAAF  +V+++V ++  P +  + G  D        
Sbjct: 3   NVLNGFKEFIMRGNAIDLAVGVIIGAAFSAVVAAIVENLFTPLIAAIFGEPDLSSVLSF- 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL---NRKKEEPAAAPAPTKE 118
                 I       G  +  V +FL VA A++  + L        RKK        P+++
Sbjct: 62  -----TINGAAFSIGAVLNAVINFLFVAIALYFFVVLPLNHLSKLRKKGIIEEPEGPSED 116

Query: 119 EVLLTEIRDLLKEQNN 134
            ++LT+IRDLL  QN 
Sbjct: 117 VLILTQIRDLLLVQNG 132


>UniRef50_D2B464 Large conductance mechanosensitive channel protein n=6
           Tax=Actinomycetales RepID=D2B464_STRRD
          Length = 134

 Score =  109 bits (273), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 7/124 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F++F MRGNVV+LA+ V+IGAAF  IV+S V D++ P +  + G  DF    + + 
Sbjct: 1   MLSGFKKFLMRGNVVELAIAVVIGAAFTAIVNSFVKDVLTPLIAAIGGQPDFSGLTLRIG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
             +       + YG+F+  +  FL+VA  I+  +    +    +          +    L
Sbjct: 61  AGE-------IRYGLFLNALIAFLMVAAVIYFLVVRPYERISARFAAREEATHRECPECL 113

Query: 123 TEIR 126
           +EI 
Sbjct: 114 SEIP 117


>UniRef50_B9CMP0 Large conductance mechanosensitive channel protein n=1
           Tax=Atopobium rimae ATCC 49626 RepID=B9CMP0_9ACTN
          Length = 142

 Score =  108 bits (271), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 44/126 (34%), Positives = 72/126 (57%), Gaps = 7/126 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL-IGGIDFKQFAVT 60
            +  EF++F  RGNV+D+A+GVIIG AF  IV+SLV DI+ P + L+  GG +    ++ 
Sbjct: 3   KLFAEFKDFIARGNVMDMAIGVIIGGAFMAIVNSLVNDIVNPFIKLISGGGTEVSGLSIP 62

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
           +   +       + +G FI  + +FLI+A  +F+ +K INK  + K+E   +P       
Sbjct: 63  VAGTEHG-----IDFGSFISAIINFLIIAVIVFLLVKAINKFMKGKKESTDSPTQVC-PH 116

Query: 121 LLTEIR 126
            L E++
Sbjct: 117 CLEEVK 122


>UniRef50_Q82H65 Putative mechanosensitive channel n=2 Tax=Streptomyces
           RepID=Q82H65_STRAW
          Length = 158

 Score =  108 bits (270), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 44/147 (29%), Positives = 66/147 (44%), Gaps = 14/147 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            ++  F+ F MRGNVVDLAV V+IGAAF  IV+S+V  II P +G   G  D  +++   
Sbjct: 8   GVLAGFKAFLMRGNVVDLAVAVVIGAAFTNIVNSVVKGIINPLVGA-FGTKDLDKYSSCF 66

Query: 62  RDA------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-------NKLNRKKEE 108
           R              + + +G  + +   F+I A  ++  + L         +  RK + 
Sbjct: 67  RAPCQVAKDGTVTKGIPIMWGTVLSSTLSFVITAAVVYFLMVLPMSKYLARMEARRKAKA 126

Query: 109 PAAAPAPTKEEVLLTEIRDLLKEQNNR 135
                    E  +L EIRD L  Q   
Sbjct: 127 GMQEVIEVTELQVLKEIRDALVAQRGP 153


>UniRef50_C8WNX6 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=C8WNX6_EGGLE
          Length = 153

 Score =  108 bits (270), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 5/119 (4%)

Query: 11  AMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPA 70
             +GNV+DLAV V+IG AF  IV+S+V+D+IMP + L+ GGIDF    + L        A
Sbjct: 12  INQGNVMDLAVAVVIGTAFTAIVNSVVSDLIMPLISLVTGGIDFSDMKIPLGTGPD---A 68

Query: 71  VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN--RKKEEPAAAPAPTKEEVLLTEIRD 127
               YG FI  V  FLI+A  +F+ +K +++     ++ +        K    L E+ +
Sbjct: 69  AAFTYGNFINAVIQFLIIALVVFLIVKALSRARMLTRRGKHIEEQDAPKCPFCLEEVNE 127


>UniRef50_D1BNK2 Large conductance mechanosensitive channel protein n=3
           Tax=Veillonella RepID=D1BNK2_VEIPT
          Length = 155

 Score =  108 bits (269), Expect = 7e-23,   Method: Composition-based stats.
 Identities = 49/138 (35%), Positives = 79/138 (57%), Gaps = 14/138 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
            + +F+ FA +GN++DLA+G+IIGAAF  +V+S+V ++ MP L +  GGIDF    + L 
Sbjct: 4   FLNDFKAFAFKGNMMDLAIGMIIGAAFTALVNSVVNNLFMPVLSVFTGGIDFSNLYLPLS 63

Query: 63  D------------AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR--KKEE 108
                        A       V+ YG FI ++  FLI+AF +F+ ++ + K+ +  K+EE
Sbjct: 64  TGSKDAFMAGADIATARAAGSVLPYGTFITDLIQFLILAFVVFLMVRGLAKMMKSAKEEE 123

Query: 109 PAAAPAPTKEEVLLTEIR 126
            A APA  + +   +EI 
Sbjct: 124 VAEAPATKECQFCKSEIN 141


>UniRef50_Q9RRR4 Large conductance mechanosensitive channel n=1 Tax=Deinococcus
           radiodurans RepID=Q9RRR4_DEIRA
          Length = 128

 Score =  108 bits (269), Expect = 7e-23,   Method: Composition-based stats.
 Identities = 42/133 (31%), Positives = 68/133 (51%), Gaps = 10/133 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  FR+F +RGNVVDLAVGV+IGAAF  +V++     + P + L  GG           
Sbjct: 1   MLNGFRDFILRGNVVDLAVGVVIGAAFNNVVAAFTKAFLDPLIRLATGG-------HGKV 53

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL---NRKKEEPAAAPAPTKEE 119
                +  +   +G F+  + +FL+ A  ++  + +         K+ E AA   P+ EE
Sbjct: 54  AGTFAVNGITFDWGTFVSTLINFLLTAAVLYFFVVMPMNAATERLKRSEKAAEAEPSNEE 113

Query: 120 VLLTEIRDLLKEQ 132
            LL EIRD ++ +
Sbjct: 114 KLLAEIRDAVRSR 126


>UniRef50_D0WJR5 Large conductance mechanosensitive channel protein n=1
           Tax=Actinomyces sp. oral taxon 848 str. F0332
           RepID=D0WJR5_9ACTO
          Length = 172

 Score =  108 bits (269), Expect = 7e-23,   Method: Composition-based stats.
 Identities = 42/133 (31%), Positives = 71/133 (53%), Gaps = 11/133 (8%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           ++I+ F++F MRGNV++LAV V+I  AF  IV++LV  +I P +G L G  +F       
Sbjct: 23  TMIEGFKKFIMRGNVIELAVAVVIADAFSPIVNNLVGKVINPTIGGLFGKPNFNNI---- 78

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN-----KLNRKKEEPAAAPAPT 116
              +  +    +  G  +  +  FL++A A+++A+         ++ ++K   A     +
Sbjct: 79  --GEFHVGDATVQPGTVLTALIAFLLIAAAVYLALVFPMNKLNERMAKRKGLNAEEAEVS 136

Query: 117 KEEVLLTEIRDLL 129
            E  LLTEIRD L
Sbjct: 137 DEVRLLTEIRDAL 149


>UniRef50_Q7UW50 Probable large-conductance mechanosensitive channel n=1
           Tax=Rhodopirellula baltica RepID=Q7UW50_RHOBA
          Length = 168

 Score =  108 bits (269), Expect = 8e-23,   Method: Composition-based stats.
 Identities = 60/154 (38%), Positives = 91/154 (59%), Gaps = 22/154 (14%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI--GGIDFKQFA 58
           M +++EF+EFA++G+V+DLAVGV+IG AF  IV SLV +IIMPP+ LL    G++FK+ A
Sbjct: 15  MGLVQEFKEFALKGSVIDLAVGVVIGGAFSGIVKSLVDNIIMPPINLLTARSGVNFKEAA 74

Query: 59  VTLRDAQGDIPAVV-----------------MHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
           +T+      +                     ++YG F Q +F+FL++A A+F+AIKLIN 
Sbjct: 75  LTIETESPKLDDAGKIIEGEGAEMLVQDYPILNYGPFTQTIFEFLLIALALFVAIKLINA 134

Query: 102 LNRKK---EEPAAAPAPTKEEVLLTEIRDLLKEQ 132
              +     E      P+++  LL EIRD L++ 
Sbjct: 135 ARSRMEDEPEEEEVAKPSEDIQLLREIRDALQKS 168


>UniRef50_B4V9Z0 Mechanosensitive channel n=3 Tax=Streptomyces RepID=B4V9Z0_9ACTO
          Length = 172

 Score =  107 bits (268), Expect = 8e-23,   Method: Composition-based stats.
 Identities = 47/144 (32%), Positives = 70/144 (48%), Gaps = 13/144 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S++  F+ F MRGNV+DLAV V+IGAAF  IV+S+V  II P +G + G      ++  L
Sbjct: 7   SVLAGFKAFLMRGNVIDLAVAVVIGAAFTNIVNSVVKGIIGPLVGAV-GTKSLDGYSSCL 65

Query: 62  RD-----AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN-------KLNRKKEEP 109
           +      A+G+   V + +G  +     F+I A  ++  + L         +  RK  E 
Sbjct: 66  KGPCGVTAKGEPTGVNILWGSVLNATLTFVITAAVVYFLMVLPMAKYLARQEQRRKAREG 125

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQN 133
                   E  +L EIRD L  Q 
Sbjct: 126 VQETMEITELEVLKEIRDTLVAQR 149


>UniRef50_C7MC43 Large conductance mechanosensitive channel protein n=1
           Tax=Brachybacterium faecium DSM 4810 RepID=C7MC43_BRAFD
          Length = 151

 Score =  107 bits (268), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 41/137 (29%), Positives = 70/137 (51%), Gaps = 10/137 (7%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K F++F M+GNV+DLAVGV+IG+AF  ++++ V ++I P +  + GG +    +  +  
Sbjct: 1   MKGFKDFVMQGNVIDLAVGVVIGSAFTALITAFVENLIQPVIN-VFGGSNVDGLSFKIIQ 59

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE------EPAAAPAPTK 117
           A     A  +  G  +  +  FLI A  ++    L     R+ +            + ++
Sbjct: 60  A---NEATRIDVGGVLSAIIAFLITAAVVYFVFVLPISAARRLDRKRRGLPEEEETSVSE 116

Query: 118 EEVLLTEIRDLLKEQNN 134
           + VLLTEIRD L  Q  
Sbjct: 117 DIVLLTEIRDALTVQQG 133


>UniRef50_C4FGI6 Putative uncharacterized protein n=1 Tax=Bifidobacterium angulatum
           DSM 20098 RepID=C4FGI6_9BIFI
          Length = 179

 Score =  107 bits (268), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 11/136 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           IK F++F  RG+++D+AVGV++G+A   +V+S+V  +I P +G++ G  D          
Sbjct: 44  IKGFKKFISRGSMIDMAVGVVMGSAVTTVVNSIVNHLISPLIGMIGGVPDMSGVL----- 98

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKKEEPAAAPAPTKEEV-- 120
                    + +G  +  + +FL++  A+++ I L INKL        A       E   
Sbjct: 99  -TITFNGATISFGAILNAIINFLLIGVAVYLCIVLPINKLRDMGANEEAENTEPTTEEQT 157

Query: 121 --LLTEIRDLLKEQNN 134
             +L EIRD LK    
Sbjct: 158 LAVLQEIRDELKRTQP 173


>UniRef50_Q82ZB4 Large-conductance mechanosensitive channel n=40 Tax=Lactobacillales
           RepID=MSCL_ENTFA
          Length = 149

 Score =  107 bits (267), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 54/137 (39%), Positives = 75/137 (54%), Gaps = 3/137 (2%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFA-VTL 61
           +IKEF+EF MRG+V+DLAVGV+IG+AF  IV+ +V  +I P + L+      K+ A   L
Sbjct: 1   MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDAL 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK--KEEPAAAPAPTKEE 119
                 +  V  + G  I  +  FLI AF +F+ +K  NK+  +  KEE A        E
Sbjct: 61  GALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSE 120

Query: 120 VLLTEIRDLLKEQNNRS 136
             L EIRDLL  Q   +
Sbjct: 121 DYLKEIRDLLAAQTPPA 137


>UniRef50_A7B9R5 Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus
           ATCC 17982 RepID=A7B9R5_9ACTO
          Length = 137

 Score =  106 bits (266), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 56/143 (39%), Positives = 79/143 (55%), Gaps = 15/143 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +I+ F+EF  RGNVV+LAVGVIIGAAF  IV +LV  II P +  +IG  DF    +   
Sbjct: 1   MIQGFKEFISRGNVVELAVGVIIGAAFKNIVDALVDGIINPLIAAVIGKPDFSDAFIL-- 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKLNRKKEEPAAA--------P 113
                +    + +GV I  V +FL++A A+++  I  +N LN + ++ AAA         
Sbjct: 59  ----TLNGTDVKFGVLITAVINFLLMAIALYLCIIVPMNALNERMKKQAAADEAEAKANK 114

Query: 114 APTKEEVLLTEIRDLLKEQNNRS 136
             + E  LLTEIRD L +   R 
Sbjct: 115 EESDEVKLLTEIRDALAQGTPRH 137


>UniRef50_B3DRI7 Large-conductance mechanosensitive channel n=17
           Tax=Actinobacteridae RepID=B3DRI7_BIFLD
          Length = 168

 Score =  106 bits (266), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 14/141 (9%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  F++F  RG+++D+AVGV++G+A   +V+S+V ++I P +G++ G  D          
Sbjct: 33  LNGFKKFLSRGSMIDMAVGVVMGSAVTAVVNSIVDNLISPLIGMIGGVPDLSGLL----- 87

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNR----KKEEPAAAPAPTKE 118
                    + +G  +  + +FL+V  A++  + L INKL      + E  A    P+ E
Sbjct: 88  -TITFNNSTVSFGAILNALINFLLVGVAVYFCVILPINKLRDLTAIQDEADAEEQGPSVE 146

Query: 119 EV---LLTEIRDLLKEQNNRS 136
           E     L EIRD LK+ N+ +
Sbjct: 147 EQTLATLQEIRDELKKANDSA 167


>UniRef50_A9KIC1 Large conductance mechanosensitive channel protein n=2
           Tax=Clostridiales RepID=A9KIC1_CLOPH
          Length = 147

 Score =  106 bits (266), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 44/128 (34%), Positives = 74/128 (57%), Gaps = 11/128 (8%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             +KEFREFA++GNV++LAVGVIIG+AF  IV+SL  +I+ P +GL     +F    + +
Sbjct: 3   KFLKEFREFALKGNVMNLAVGVIIGSAFQGIVTSLTDNILSPIIGLFTRQ-NFDSLQLNI 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK---LNRKKEEPAAAPAPTKE 118
                    + + YG FI  + +F+I+AF +F+ +K +N+    + K+++    P     
Sbjct: 62  F-------GITLRYGAFITALINFVIMAFVVFLLVKGMNRILSFDDKRKKVEVKPTEKDC 114

Query: 119 EVLLTEIR 126
              +T+I 
Sbjct: 115 PYCMTKIN 122


>UniRef50_A0JZ24 Large conductance mechanosensitive channel protein n=1
           Tax=Arthrobacter sp. FB24 RepID=A0JZ24_ARTS2
          Length = 130

 Score =  106 bits (264), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 19/141 (13%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  F+ F M+GNVVDLAV V++GAAF  +V+S+V  ++ P +G L      +        
Sbjct: 1   MTGFKNFIMKGNVVDLAVAVVMGAAFSAVVTSIVEGLLTPLIGRLFNAKGIEDMQWE--- 57

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL-INKLNRKK-------EEPAAAPAP 115
                      YG  I +V  FL+V  +I+  + L +N +  ++        E     A 
Sbjct: 58  --------GFMYGSVISSVISFLLVGASIYFVVVLPMNHMIERRNRRLGIGTEVKEEAAE 109

Query: 116 TKEEVLLTEIRDLLKEQNNRS 136
             +  LLTEIRD L+  + R+
Sbjct: 110 DPQIALLTEIRDSLRSGSTRA 130


>UniRef50_B8ZU13 Large-conductance mechanosensitive channel n=23 Tax=Mycobacterium
           RepID=MSCL_MYCLB
          Length = 154

 Score =  106 bits (264), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 41/134 (30%), Positives = 66/134 (49%), Gaps = 6/134 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + + F+EF  RGN+VDLAV V+IG AF  +++     II P +  +  G++ +     LR
Sbjct: 1   MFRGFKEFLSRGNIVDLAVAVVIGTAFTALITKFTDSIITPLINRV--GVNQQTNISPLR 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP--TKEEV 120
              G   A+ ++    +    +FL++A  ++  + L     RK  E           + V
Sbjct: 59  IDIGGDQAIDLNI--VLSAAINFLLIALVVYFLVVLPYTTIRKHGEVEQFDTDLIGNQVV 116

Query: 121 LLTEIRDLLKEQNN 134
           LL EIRDLL + N 
Sbjct: 117 LLAEIRDLLAQSNG 130


>UniRef50_B4D701 Large conductance mechanosensitive channel protein n=2
           Tax=Verrucomicrobia RepID=B4D701_9BACT
          Length = 141

 Score =  105 bits (263), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 51/131 (38%), Positives = 68/131 (51%), Gaps = 14/131 (10%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           EF+ F M+GNV+DLAVG++IGAAFG +V      II P +G   GG D            
Sbjct: 9   EFKTFIMKGNVIDLAVGLLIGAAFGAVVKDFTDGIINPLIGYFGGGKDVS---------- 58

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFMA-IKLINKLNRKKEEPAA-APAPTKEEVLLT 123
             +   +   G+ I  +  FLI A  +F   +K +NKL    E+  A AP P ++  LL 
Sbjct: 59  --LHLWIFDVGLVINAIIKFLITAVVLFFIFVKPMNKLKAMSEKKEAGAPPPPEDIQLLR 116

Query: 124 EIRDLLKEQNN 134
           EIRDLLK    
Sbjct: 117 EIRDLLKAGAK 127


>UniRef50_A9HW97 Large-conductance mechanosensitive channel n=98 Tax=Proteobacteria
           RepID=MSCL_BORPD
          Length = 148

 Score =  105 bits (262), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 62/143 (43%), Positives = 91/143 (63%), Gaps = 13/143 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAVT 60
             +KEFR+FA++GN +DLAVGVIIGAAFGKIV S+V D+IMP +  ++GG +DF    + 
Sbjct: 6   GFLKEFRDFAVKGNAIDLAVGVIIGAAFGKIVDSVVKDLIMPLVNYILGGSVDFSNKFLV 65

Query: 61  LRDAQG-----------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK-KEE 108
           L    G              A+V+ +G F+  + +F+++A  +F+ +K IN   RK +E 
Sbjct: 66  LSAPDGYAGPMTYADLTKAGAIVLAWGNFLTILINFILLALVVFIIVKAINAARRKEEEA 125

Query: 109 PAAAPAPTKEEVLLTEIRDLLKE 131
           PA   AP ++ V+L EIRDLLK+
Sbjct: 126 PAEPAAPPEDVVVLREIRDLLKK 148


>UniRef50_D2R1B6 Large conductance mechanosensitive channel protein n=1
           Tax=Pirellula staleyi DSM 6068 RepID=D2R1B6_9PLAN
          Length = 166

 Score =  105 bits (261), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 68/166 (40%), Positives = 89/166 (53%), Gaps = 34/166 (20%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGI-DFKQFAV 59
           M ++KEFR+FA+RGNV+DLAVGVIIG AFGKI SSLV D++MP LGL+     DFK   +
Sbjct: 1   MGLLKEFRDFALRGNVIDLAVGVIIGGAFGKITSSLVGDVMMPALGLVANNALDFKSRYI 60

Query: 60  TLRDAQGDIPAV--------------------------VMHYGVFIQNVFDFLIVAFAIF 93
            L  A+    A                           V+ YG F+  V DF I+AF +F
Sbjct: 61  RLFSAEQLAAATKTTTEEANKLIDSGVPFSIVSENKLPVIAYGSFLTTVIDFAILAFCVF 120

Query: 94  MAIKLINKLNRKKEE-------PAAAPAPTKEEVLLTEIRDLLKEQ 132
           M +K++N   ++ E         A    P  +E LL EIRDLLK +
Sbjct: 121 MVVKIMNTAIKRLEALRKAEVAAAPPAEPPAQEKLLMEIRDLLKAK 166


>UniRef50_A4AI90 Large-conductance mechanosensitive channel n=1 Tax=marine
           actinobacterium PHSC20C1 RepID=A4AI90_9ACTN
          Length = 137

 Score =  104 bits (260), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 45/138 (32%), Positives = 68/138 (49%), Gaps = 6/138 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++  F+ F +RGNV+DLAV V+IGAAF  +V+++V  +  P +G L         A+ + 
Sbjct: 1   MLSGFKTFILRGNVIDLAVAVVIGAAFTAVVNTIVEAVFNPLIGALFNAETLST-ALPVT 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK-----KEEPAAAPAPTK 117
                    V+++G  I  +  FL+VA  ++ AI        K     K       A   
Sbjct: 60  IPTAGGEDAVIYFGAVIAALVQFLLVAVVVYFAIVAPMNYANKLAAARKPVVIEPEAGPT 119

Query: 118 EEVLLTEIRDLLKEQNNR 135
           E  LL +IRDLL +QNN 
Sbjct: 120 EAELLLQIRDLLAKQNNS 137


>UniRef50_A8LHK6 Large conductance mechanosensitive channel protein n=5
           Tax=Actinomycetales RepID=A8LHK6_FRASN
          Length = 169

 Score =  103 bits (258), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 48/130 (36%), Positives = 71/130 (54%), Gaps = 13/130 (10%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           ++ F++F MRGN+VDLA+ V++G AF  +V SLV +I  P +  + G  DF     T+ D
Sbjct: 26  LRGFKQFLMRGNIVDLAIAVVVGTAFTAVVQSLVKNIFTPLIAAIGGEPDFSSLTFTIND 85

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI------NKLNRKKEEPAAAPAPTK 117
           ++         YG FI +V  F++VA  I+  I L        +   ++ EP   PA + 
Sbjct: 86  SK-------FRYGAFINDVIAFIVVAAVIYFVIVLPLAKANEMRRRGEEPEPQEEPAISD 138

Query: 118 EEVLLTEIRD 127
           E  LLTEIRD
Sbjct: 139 EAKLLTEIRD 148


>UniRef50_A3CM47 Large conductance mechano-sensitive ion channel, putative n=44
           Tax=Streptococcus RepID=A3CM47_STRSV
          Length = 127

 Score =  103 bits (258), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 51/135 (37%), Positives = 77/135 (57%), Gaps = 12/135 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP-LGLLIGGIDFKQFAVTL 61
           ++K+ +EF +RGNV+DLAVGVII  AFG IV+SL+ D+I P  L  ++   + +Q +   
Sbjct: 1   MLKDLKEFLLRGNVIDLAVGVIIANAFGAIVTSLITDVITPLFLNPILKAANLEQISQLK 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK---LNRKKEEPAAAPAPTKE 118
            +         + YG F+  V +FL++   +F  +K   K   L +KKEE   APA   E
Sbjct: 61  WNG--------IAYGNFLSAVINFLVIGTVLFFIVKSAEKAQSLAKKKEEVEEAPAGPTE 112

Query: 119 EVLLTEIRDLLKEQN 133
             +L EI+ LL E+ 
Sbjct: 113 LEVLQEIKALLAEKK 127


>UniRef50_B0T274 Large-conductance mechanosensitive channel n=42 Tax=Bacteria
           RepID=MSCL_CAUSK
          Length = 161

 Score =  103 bits (258), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 71/137 (51%), Positives = 85/137 (62%), Gaps = 6/137 (4%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           MSI+KEFREF  RGNVVDLAVGVIIGAAF  IV SLV  +IMPP+GL+ GG+DF +    
Sbjct: 1   MSIVKEFREFIARGNVVDLAVGVIIGAAFNGIVKSLVDGVIMPPIGLVTGGLDFSKLQWV 60

Query: 61  LRDAQGDIPA---VVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTK 117
           L+       A   V + YG FI  V  FLIVA  +F+ +KL+N + R      A  AP  
Sbjct: 61  LKPEDPVTEAVELVAIQYGAFINTVIQFLIVAVVVFLLVKLVNHIRRADAAEPAPEAPAA 120

Query: 118 EEV---LLTEIRDLLKE 131
                 LLTEIRDLL +
Sbjct: 121 PTPEERLLTEIRDLLAK 137


>UniRef50_Q04FK1 Large-conductance mechanosensitive channel n=4 Tax=Leuconostocaceae
           RepID=MSCL_OENOB
          Length = 129

 Score =  103 bits (256), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 55/134 (41%), Positives = 80/134 (59%), Gaps = 8/134 (5%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++ EF++F MRGN +DLAVGV++GAAF  IV S+V ++I P +G+  G +D      ++ 
Sbjct: 1   MLNEFKQFIMRGNAIDLAVGVVMGAAFTSIVKSIVTNLIGPIIGIFAGAVDLSSLKFSIG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
            A       V  YG  +  V +F+IV F IF+ IK INK  +K E+   A A + E  LL
Sbjct: 61  PA-------VFKYGAVLNQVINFIIVGFIIFLIIKAINKFFKKNEKKEDAEAES-EVKLL 112

Query: 123 TEIRDLLKEQNNRS 136
           T+IR  LK+ N  +
Sbjct: 113 TDIRAELKKSNQST 126


>UniRef50_A7X204 Large-conductance mechanosensitive channel n=51 Tax=Staphylococcus
           aureus RepID=MSCL_STAA1
          Length = 120

 Score =  103 bits (256), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 61/131 (46%), Positives = 90/131 (68%), Gaps = 11/131 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNV+DLA+ V++GAAF KI+SSLV +IIMP +G + G +DF +      
Sbjct: 1   MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAK------ 54

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               +     + YG+FIQ+V DF+I+AFA+F+ +K+ N L +K+E    A       VLL
Sbjct: 55  ----EWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAEEEAVVEEN-VVLL 109

Query: 123 TEIRDLLKEQN 133
           TEIRDLL+E+ 
Sbjct: 110 TEIRDLLREKK 120


>UniRef50_C7HUU0 Large conductance mechanosensitive channel protein n=2
           Tax=Anaerococcus RepID=C7HUU0_9FIRM
          Length = 135

 Score =  103 bits (256), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 42/124 (33%), Positives = 67/124 (54%), Gaps = 10/124 (8%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + KEF+EF  +GNVVDLA+G+I+G+AF  IV+++V  I+MP +  L  G+D++  AV   
Sbjct: 1   MWKEFKEFISKGNVVDLAIGLIMGSAFTAIVTAVVDGILMPIISGLTAGVDYEDLAVNFF 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
            A+       +  G  I  +  FLI++  +F+ +K +NK  +   E              
Sbjct: 61  GAK-------LQIGSVINAIITFLIISLFLFLIVKALNKAKK---EEVVEATTKICPHCK 110

Query: 123 TEIR 126
           TEI 
Sbjct: 111 TEIN 114


>UniRef50_Q31LP8 Large-conductance mechanosensitive channel n=2 Tax=Synechococcus
           elongatus RepID=MSCL_SYNE7
          Length = 133

 Score =  103 bits (256), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 51/135 (37%), Positives = 78/135 (57%), Gaps = 13/135 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           +  I++F+ F ++GNVV+LAV VIIG AF KIVSS V D++MP +  LI G D++   + 
Sbjct: 9   VGFIRDFQAFILKGNVVELAVAVIIGGAFNKIVSSFVGDLVMPLVNPLIPGGDWRTAVI- 67

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
                       +  G F  +V DFLI+AF +++AI+ I +  RK+E   AA  P  ++ 
Sbjct: 68  ---------GPGLKIGSFAGSVIDFLIIAFVLYLAIRAIERFKRKEEAVVAAAEPDVQQQ 118

Query: 121 L---LTEIRDLLKEQ 132
           +   L  I D L+ +
Sbjct: 119 MLATLERIADNLEAR 133


>UniRef50_B0S3E4 Large-conductive mechanosensitive channel n=2 Tax=Finegoldia magna
           RepID=B0S3E4_FINM2
          Length = 133

 Score =  103 bits (256), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 45/124 (36%), Positives = 71/124 (57%), Gaps = 8/124 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF++F   GNV+DLAV VI+GAA  ++V  L+  +I P +G    G++ K+ AVTL 
Sbjct: 1   MLKEFKKFITEGNVMDLAVAVIMGAAVKEMVDGLINGLIAPLIGAATAGVNMKELAVTL- 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK-KEEPAAAPAPTKEEVL 121
                   V + YG+F+  +  F+I+AF +F+ +K +NK      +EPA  P        
Sbjct: 60  ------AGVKLQYGLFLDALVKFIIIAFVVFIMVKAVNKGRDALHKEPAPEPTTKTCPYC 113

Query: 122 LTEI 125
            +EI
Sbjct: 114 KSEI 117


>UniRef50_D2MPY5 Large conductance mechanosensitive channel protein n=1
           Tax=Bulleidia extructa W1219 RepID=D2MPY5_9FIRM
          Length = 125

 Score =  102 bits (255), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 49/131 (37%), Positives = 82/131 (62%), Gaps = 8/131 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + + EF+EFA++GNV+DLAVGVIIG AF  I+ SL+ +II P +G+L    DF Q  + +
Sbjct: 3   NFMNEFKEFALKGNVMDLAVGVIIGGAFQAIIKSLIDNIINPIIGILF-QADFSQVVIRM 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                   +V +  G F+  + +F+++AF +F+ +K IN+L +  +E  + P  ++E  L
Sbjct: 62  -------GSVNLGVGAFVSTIINFVLLAFVLFLMVKAINQLKKLNQEEESTPEKSEEAQL 114

Query: 122 LTEIRDLLKEQ 132
           L +I + LK+ 
Sbjct: 115 LEKILEQLKKN 125


>UniRef50_A7VB12 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
           RepID=A7VB12_9CLOT
          Length = 141

 Score =  102 bits (255), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 47/125 (37%), Positives = 69/125 (55%), Gaps = 9/125 (7%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
              +EF+EFA++GNV+D+A+GVIIG AF  +V+SL    I P +G + G          +
Sbjct: 3   KFFQEFKEFALKGNVLDMAIGVIIGGAFSGLVTSLTDCFINPIIGCIGGA--------EV 54

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR-KKEEPAAAPAPTKEEV 120
           +     +    + YG FI  V +F+I+AF IF+ +K I KL    K+E AAAP   K   
Sbjct: 55  QGKIHLLGDQYIDYGSFITAVINFIIMAFIIFLLMKGIKKLLSLGKKEEAAAPLTRKCPY 114

Query: 121 LLTEI 125
              +I
Sbjct: 115 CYGDI 119


>UniRef50_B5Y8I7 Large conductance mechanosensitive channel protein n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y8I7_COPPD
          Length = 127

 Score =  102 bits (254), Expect = 4e-21,   Method: Composition-based stats.
 Identities = 46/138 (33%), Positives = 67/138 (48%), Gaps = 19/138 (13%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F+ F  RGNV+DLA+ VIIGAAF  +V SLV DI  P LG+L G  DF  + V   
Sbjct: 1   MLKGFKAFLSRGNVLDLAIAVIIGAAFNSVVKSLVEDIFTPLLGMLGGLPDFSSWKV--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL--------NRKKEEPAAAPA 114
                     +  G F+ ++  FL  A  I+  +    +          R +    A   
Sbjct: 58  --------GPLMLGSFVNSLLSFLFTAAVIYFVLVAPAEALKNAAKEKQRAETLDKATET 109

Query: 115 PTKEEVLLTEIRDLLKEQ 132
           P +E  LL  I +LL+++
Sbjct: 110 PPEEIQLLRRIVELLEKK 127


>UniRef50_D1AZE9 Large conductance mechanosensitive channel protein n=1
           Tax=Sulfurospirillum deleyianum DSM 6946
           RepID=D1AZE9_SULD5
          Length = 142

 Score =  101 bits (253), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 48/125 (38%), Positives = 70/125 (56%), Gaps = 12/125 (9%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+ F ++GNV+D+AVG I GAAF  +V SLV++IIMPP+GLL+G +DF    + L 
Sbjct: 1   MLKEFKNFLIKGNVIDMAVGFIFGAAFATVVKSLVSNIIMPPVGLLLGNVDFSSLFIALD 60

Query: 63  DAQ-------GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAP 115
             +           A  +  GVF  +   F+I+ F +FM IK   K+      P   P P
Sbjct: 61  GKEYVSLADLEKAGAPAIKLGVFFNDFTSFIILGFVMFMMIKGYAKI-----APKEEPLP 115

Query: 116 TKEEV 120
           T +  
Sbjct: 116 TTKVC 120


>UniRef50_A4F7T6 Large-conductance mechanosensitive channel n=3 Tax=Actinomycetales
           RepID=A4F7T6_SACEN
          Length = 158

 Score =  101 bits (253), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 5/133 (3%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F MRGNVVDLAV V++G+AF  +V++    II P +    GG +    ++ L 
Sbjct: 1   MLKGFKDFLMRGNVVDLAVAVVVGSAFTALVTAFTTSIIKPVIAA-TGGGNVTGLSIQL- 58

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK-LNRKKEEPAAAPAPTKEEVL 121
                    ++ +   I  V  F I A  ++    L  K L  ++E          +  L
Sbjct: 59  --VAGNQQSIIDFAQVINAVITFFITAAVVYFIFVLPMKTLKERRERGKETEVAPTDVEL 116

Query: 122 LTEIRDLLKEQNN 134
           L EIRDLL+ +  
Sbjct: 117 LLEIRDLLRREQG 129


>UniRef50_Q8DHB2 Large-conductive mechanosensitive channel n=1
           Tax=Thermosynechococcus elongatus BP-1
           RepID=Q8DHB2_THEEB
          Length = 140

 Score =  101 bits (251), Expect = 8e-21,   Method: Composition-based stats.
 Identities = 40/116 (34%), Positives = 66/116 (56%), Gaps = 11/116 (9%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
             +EFREFA++GNV+DLA+ V++G AF +IV+S+V D+IMP +  LI G D+++  +   
Sbjct: 14  FWQEFREFALKGNVIDLAIAVVVGGAFSRIVTSVVEDLIMPLVNPLIPGGDWRELTL--- 70

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR-KKEEPAAAPAPTK 117
                     M  G F+ ++ DF ++A ++F+ +KLI      +   P     P  
Sbjct: 71  -------GSGMRIGKFLGSLLDFGVIALSLFILLKLILPFLPNRPPAPEQRQCPYC 119


>UniRef50_Q5SKL6 Large-conductance mechanosensitive channel n=2 Tax=Thermus
           thermophilus RepID=Q5SKL6_THET8
          Length = 124

 Score =  101 bits (251), Expect = 8e-21,   Method: Composition-based stats.
 Identities = 47/135 (34%), Positives = 72/135 (53%), Gaps = 15/135 (11%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + ++ ++F MRGNVVDLAV VIIG AF ++VSSLVAD+I P +G L G  DF    +   
Sbjct: 1   MWRDLKDFLMRGNVVDLAVAVIIGTAFSQVVSSLVADVITPLIGALGGVPDFSGIRL--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN----RKKEEPAAAPAPTKE 118
                     +  G F+  + +FLIV   ++  + +  +      RK  +    P P +E
Sbjct: 58  --------GPIALGRFLNALLNFLIVGTTVYFLVVVPMREAQKRLRKPPQETPPPEPPEE 109

Query: 119 EVLLTEIRDLLKEQN 133
             LL EI + L+++ 
Sbjct: 110 IRLLREILEELRKKT 124


>UniRef50_C5RAB3 MscL family large conductance mechanosensitive ion channel n=1
           Tax=Weissella paramesenteroides ATCC 33313
           RepID=C5RAB3_WEIPA
          Length = 130

 Score =  101 bits (251), Expect = 8e-21,   Method: Composition-based stats.
 Identities = 53/135 (39%), Positives = 76/135 (56%), Gaps = 9/135 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           + I EF++F MRGNV+DLAV  I+GAAF  +V S+V D+IMP +G++ G I F      +
Sbjct: 3   NFINEFKDFIMRGNVMDLAVAFIMGAAFQTVVKSVVDDLIMPLIGIITGSISFSSIVWHV 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR--KKEEPAAAPAPTKEE 119
             A        +  G FI  +  FL+ +FA+F+ +K I K     KK+      AP  E 
Sbjct: 63  GSAD-------IKVGSFIGTLITFLLTSFAVFLILKAIRKAQSMTKKQAEEEEIAPETEL 115

Query: 120 VLLTEIRDLLKEQNN 134
           V+L EIRD L  + +
Sbjct: 116 VVLQEIRDALAAKKD 130


>UniRef50_C0QYW6 Large-conductance mechanosensitive channel n=2 Tax=Brachyspira
           RepID=MSCL_BRAHW
          Length = 155

 Score =  100 bits (249), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 48/113 (42%), Positives = 76/113 (67%), Gaps = 12/113 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IKEF++F M+G+++D+AVG++IGAAF KIV+S V DI+MPP+G+++ GIDF    + ++
Sbjct: 1   MIKEFKKFIMKGSILDMAVGLVIGAAFTKIVNSFVDDILMPPIGMILSGIDFSNIFIVIK 60

Query: 63  ------------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN 103
                       +A  +  AVV+  GVFI  +  F+I A ++F+ IKL NK+ 
Sbjct: 61  KGTDTLGNYNSIEAARNAGAVVIGIGVFINAIISFIITALSLFIIIKLFNKIQ 113


>UniRef50_C4FVI2 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FVI2_9FIRM
          Length = 128

 Score =  100 bits (248), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 47/133 (35%), Positives = 70/133 (52%), Gaps = 8/133 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            I +EFR F  + N++ LAV VI+G AF  IV+SLV DI MP L  + G       A+ +
Sbjct: 3   KIFEEFRGFIAKDNIITLAVAVILGGAFSSIVTSLVNDIFMPILVAVTGQATVSGIALRI 62

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK-EEPAAAPAPTKEEV 120
                      +  G F+Q V +F+I+ F +F+ +K + K   K    P A PA   E+ 
Sbjct: 63  -------GNTYLGVGNFLQAVINFVIIGFLLFLTLKALGKAQGKDLINPPAPPAGPSEKD 115

Query: 121 LLTEIRDLLKEQN 133
           LL +I + LK++ 
Sbjct: 116 LLQDILNELKKEK 128


>UniRef50_Q9P639 Related to large-conductance mechanosensitive channel n=8
           Tax=Leotiomyceta RepID=Q9P639_NEUCR
          Length = 373

 Score = 97.3 bits (241), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 36/130 (27%), Positives = 66/130 (50%), Gaps = 16/130 (12%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-------------- 49
            ++F  FA +GNV+++A G+I+   F  +V+S V+DI++PP+ +L+              
Sbjct: 28  WEDFVGFAFQGNVLEIAFGLILATMFTALVTSFVSDIVLPPISVLLPLNKNLEEKFAVLR 87

Query: 50  -GGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
            G    ++   TL+ AQ D  AVVM YG F+  + +F+ V F+++    +   +++    
Sbjct: 88  SGANHPEEGYNTLKQAQAD-GAVVMAYGFFMNRLLNFMGVGFSLYSIASIYQWMSKDPII 146

Query: 109 PAAAPAPTKE 118
               P P   
Sbjct: 147 KKTVPCPYCC 156


>UniRef50_B2IVG3 Large conductance mechanosensitive channel protein n=2
           Tax=Cyanobacteria RepID=B2IVG3_NOSP7
          Length = 144

 Score = 97.3 bits (241), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 43/123 (34%), Positives = 73/123 (59%), Gaps = 9/123 (7%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             +++F+EFA +GNV+DLA+ VIIG AF ++++S V D+IMP +  LIG        VT 
Sbjct: 10  GFLRDFQEFAFKGNVIDLAIAVIIGTAFSRVITSFVEDVIMPLINPLIG--------VTG 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
           ++ +       +  G F+  + DFLI+A  +F+AI+ +    R++E P  + +P+   V+
Sbjct: 62  KEWRTITIGPGIAIGQFLGAIIDFLIIALILFVAIRTLQTFKRQEEVPVES-SPSDANVI 120

Query: 122 LTE 124
             E
Sbjct: 121 AQE 123


>UniRef50_A1RBS3 Large conductance mechanosensitive channel protein n=7
           Tax=Actinomycetales RepID=A1RBS3_ARTAT
          Length = 154

 Score = 96.2 bits (238), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 37/134 (27%), Positives = 66/134 (49%), Gaps = 10/134 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + K F++F +RGNV++LA+ V+IG+AF  +V++   +II P +    GG++       + 
Sbjct: 1   MFKGFKDFILRGNVIELAIAVVIGSAFTALVTAFTNNIINPVIAAA-GGMNADGLGFKIW 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK------LNRKKEEPAAAPAPT 116
           +   + PA +++ G  +  +  F+I A  ++               +R   E        
Sbjct: 60  E---NNPATLVNIGAVLTALVTFVITAAVVYFIFVAPMNKINSLVKDRLSTEEPEEEPLP 116

Query: 117 KEEVLLTEIRDLLK 130
            +  LL EIRDLLK
Sbjct: 117 ADTALLAEIRDLLK 130


>UniRef50_A5UVR8 Large-conductance mechanosensitive channel n=2 Tax=Roseiflexus
           RepID=MSCL_ROSS1
          Length = 126

 Score = 96.2 bits (238), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 55/134 (41%), Positives = 79/134 (58%), Gaps = 14/134 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + + F+ F MRGNV+DLAVGV+IG AF  +V+SLV DI+M  +  LIG  DF    V   
Sbjct: 1   MFEGFKTFVMRGNVIDLAVGVVIGTAFSAVVNSLVNDILMAIVATLIGQPDFSDVLV--- 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI----NKLNRKKEEPAAAPAPTKE 118
                     +  G FI  + +FLI++ A++  + +     ++  R+ E P A PAP+ E
Sbjct: 58  -------FGAVRLGAFITTIVNFLIISAALYFLVVVPINKLSEFTRRNEPPPAPPAPSAE 110

Query: 119 EVLLTEIRDLLKEQ 132
           E LLTEIRDLL++ 
Sbjct: 111 EKLLTEIRDLLRQN 124


>UniRef50_C1AX17 Large-conductance mechanosensitive channel n=2 Tax=Rhodococcus
           RepID=C1AX17_RHOOB
          Length = 155

 Score = 96.2 bits (238), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 42/130 (32%), Positives = 69/130 (53%), Gaps = 4/130 (3%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F +RGNV+DLAV V++GAAF  IV+S   ++I P + +  G  D       L 
Sbjct: 1   MLKGFKDFLLRGNVLDLAVAVVVGAAFTAIVTSFTNNVINPLIAVAGGANDLGWGYQIL- 59

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               D PA  ++ G  I  V +F+I+A  ++  + +     +K+     A     E  LL
Sbjct: 60  ---ADNPATFINIGAVITAVINFVIIAAVVYFILIVPANAAKKRFITEPADKKASEADLL 116

Query: 123 TEIRDLLKEQ 132
            +IRD+L+  
Sbjct: 117 IQIRDILEAS 126


>UniRef50_C6R3M2 Large conductance mechanosensitive channel protein n=1 Tax=Rothia
           mucilaginosa ATCC 25296 RepID=C6R3M2_9MICC
          Length = 147

 Score = 95.4 bits (236), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 44/134 (32%), Positives = 76/134 (56%), Gaps = 14/134 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++K F++F +RGNV+DLAVG+I+G AF  +V++LV  ++MP + +L+   +F +F V  +
Sbjct: 24  MLKGFKDFLIRGNVIDLAVGLIMGTAFTAVVNALVQSVLMPAISMLVKSPNFDEFLVFDQ 83

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI----NKLNRKKEEPAAAPAPTKE 118
                     +  GVF+  V +F+++A A++ A+ L      +L  K +          E
Sbjct: 84  ----------IKVGVFLTAVVNFILIAAAVYFAVVLPVQKLTELAAKNKAEEEEEEEETE 133

Query: 119 EVLLTEIRDLLKEQ 132
             LL EIRD L ++
Sbjct: 134 IALLKEIRDALAKK 147


>UniRef50_Q6AAH3 Large conductance mechanosensitive channel n=4 Tax=Bacteria
           RepID=Q6AAH3_PROAC
          Length = 122

 Score = 95.4 bits (236), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 44/131 (33%), Positives = 64/131 (48%), Gaps = 14/131 (10%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K F++F MRGN+++LAV  I+G AF  +V S    IIM  +G L G  +F  +      
Sbjct: 1   MKGFKDFLMRGNLIELAVAFILGGAFSTVVKSFTT-IIMDLIGKLGGTPNFSGWV----- 54

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFM-AIKLINKLNRKKEEPAAAP-APTKEEVL 121
                    +H G FI +V  F +++F I+   IK I     K +     P A      L
Sbjct: 55  ------PGGVHVGAFITDVISFFVMSFVIYFGLIKPIELATEKLKRTKDEPVAAPTTADL 108

Query: 122 LTEIRDLLKEQ 132
           L EIRD L+ +
Sbjct: 109 LIEIRDELRSR 119


>UniRef50_Q8EW76 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           penetrans RepID=Q8EW76_MYCPE
          Length = 215

 Score = 95.4 bits (236), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 9/110 (8%)

Query: 4   IKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGI--------DF 54
            KEF++    RGN++DLAV +IIG AF  IV+SLV DIIMP +G   G          D 
Sbjct: 19  WKEFKKLVSSRGNLIDLAVALIIGTAFTAIVTSLVNDIIMPLIGAAAGKSLSELVWYLDI 78

Query: 55  KQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
                 L +   +  A+++ YG F+Q + +F I+A  +F  +K    + +
Sbjct: 79  NNQPHFLPNGDINPQAIIIKYGNFLQVIINFFIIALTMFSVVKAYLSIRK 128


>UniRef50_B1V916 Putative large-conductance mechanosensitive channel n=1
           Tax=Candidatus Phytoplasma australiense
           RepID=B1V916_PHYAS
          Length = 134

 Score = 95.0 bits (235), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 49/129 (37%), Positives = 74/129 (57%), Gaps = 10/129 (7%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGI-DFKQFAV 59
           M+  + F+ F  RGNV++LAV V+IG  F KIVSSLVADI+MPP  LL       +    
Sbjct: 1   MTFFQGFKNFITRGNVINLAVAVVIGQLFSKIVSSLVADIMMPPFSLLFNETKGLQGLKW 60

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL---NRKKEEPAAAPAPT 116
            +++       V M+YG+F+QN+ +F+I +FAI++ + + ++      K E      +  
Sbjct: 61  CIKE------DVYMNYGIFLQNILEFVIFSFAIYLILTIFSRTKLEKPKSELKLILESLQ 114

Query: 117 KEEVLLTEI 125
           KE  LL EI
Sbjct: 115 KEITLLQEI 123


>UniRef50_P73553 Large-conductance mechanosensitive channel n=2 Tax=Chroococcales
           RepID=MSCL_SYNY3
          Length = 145

 Score = 95.0 bits (235), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 11/122 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
              ++F++F +RGNVVDLAV V+IG AF  IV++ VA ++   L  ++      Q     
Sbjct: 11  GFWRDFKDFILRGNVVDLAVAVVIGGAFTSIVNAFVAWLMAVLLQPVLDQAGVSQL---- 66

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                    + +  G  +  + +FLI+AF IF+ IK I K+ RKK       A  + + +
Sbjct: 67  -------QDLPLGLGELVIAIINFLIIAFVIFLIIKAIEKMQRKKAVEEEIVAEAQPDPV 119

Query: 122 LT 123
           L 
Sbjct: 120 LE 121


>UniRef50_Q025U4 Large conductance mechanosensitive channel protein n=1
           Tax=Candidatus Solibacter usitatus Ellin6076
           RepID=Q025U4_SOLUE
          Length = 136

 Score = 94.6 bits (234), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 43/122 (35%), Positives = 66/122 (54%), Gaps = 3/122 (2%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK F+EF ++ NV+ LAV VI+G A GK+VSSL AD+IMP + L++   D++     L 
Sbjct: 1   MIKGFKEFLLKNNVLALAVAVIVGGAVGKVVSSLAADVIMPVISLVLPAGDWRTAKFVLG 60

Query: 63  ---DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEE 119
                 G      ++YG F  +V DFLI+A  +++  K + K       P     P  +E
Sbjct: 61  KTVGPDGKETLNTLNYGSFFGSVVDFLIIALVVYLMTKALIKEAPAPAPPPTKNCPRCKE 120

Query: 120 VL 121
            +
Sbjct: 121 AI 122


>UniRef50_C7H9Q8 Large conductance mechanosensitive channel protein n=1
           Tax=Faecalibacterium prausnitzii A2-165
           RepID=C7H9Q8_9FIRM
          Length = 152

 Score = 94.6 bits (234), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 44/101 (43%), Positives = 63/101 (62%), Gaps = 8/101 (7%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
              +EF+ FAMRGNV+D+AVGV++G+AF  IV+SLV D+I P +GL     DF +  V +
Sbjct: 11  KFFEEFKAFAMRGNVLDMAVGVVVGSAFTAIVNSLVGDVINPLIGLFFN-NDFSEVVVKI 69

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL 102
            D       V +  G FI  + +FLIVAF +F+ +K  N +
Sbjct: 70  GD-------VDLKIGSFISAIINFLIVAFVLFLVLKAFNAV 103


>UniRef50_D0P2C5 Large Conductance Mechanosensitive Ion Channel (MscL) Family n=2
           Tax=Phytophthora infestans T30-4 RepID=D0P2C5_PHYIN
          Length = 191

 Score = 94.2 bits (233), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 38/133 (28%), Positives = 70/133 (52%), Gaps = 15/133 (11%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-GGIDFKQFA-- 58
           +++ +F+EF  +GN++++AVG+I+G++F  I++SLV DI+ P + L    GI    +   
Sbjct: 35  ALLTDFQEFIQQGNMLNMAVGLILGSSFSAILNSLVVDILSPIISLFTERGIANHYWPVR 94

Query: 59  ------------VTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK 106
                               D  AV ++YG+FI+N+ +F+I A  +F+A+K   +   K 
Sbjct: 95  CPSTTTVCSGETWQTWKEARDAGAVTINYGLFIENIMNFVINALFLFIAVKKALEFVFKL 154

Query: 107 EEPAAAPAPTKEE 119
           +       P  +E
Sbjct: 155 KVGVKKQCPYCKE 167


>UniRef50_Q1QDU6 Large-conductance mechanosensitive channel n=5 Tax=Bacteria
           RepID=MSCL_PSYCK
          Length = 149

 Score = 94.2 bits (233), Expect = 1e-18,   Method: Composition-based stats.
 Identities = 54/116 (46%), Positives = 75/116 (64%), Gaps = 11/116 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG-IDFKQFAV 59
           MS++ EF+EFA++GNV+DLAVGVIIG AF  I  SLV D+IMP +  ++GG I+FK   +
Sbjct: 1   MSMVSEFKEFALKGNVMDLAVGVIIGGAFATITKSLVEDVIMPIVAFIVGGEINFKNMFL 60

Query: 60  TLRDAQGDIPAV----------VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK 105
            L DA   +             V+ YG FI  + +FLI+AF IFM +K++N+L R 
Sbjct: 61  ILGDAPEGVARTNDALKAAGIPVLAYGSFITVLINFLILAFIIFMMVKMVNRLRRA 116


>UniRef50_B6HL82 Pc21g07880 protein n=6 Tax=Trichocomaceae RepID=B6HL82_PENCW
          Length = 201

 Score = 93.5 bits (231), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 17/134 (12%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL--------------- 48
              F  FA R NV+++A+G+II  AF K+V+S V D+++P + LL               
Sbjct: 26  WDGFINFAARDNVLEVALGLIIANAFTKVVTSFVTDMVLPIVSLLPFLNRNMDQKFAVLS 85

Query: 49  -IGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
                D +    TL  A+ D  A+V+ YG F++   +FL V+  ++    L   + + K 
Sbjct: 86  KGPNFDQQNGYNTLLQARED-GALVLAYGAFMETALNFLGVSLTLYAVGHLYMLIFQDKI 144

Query: 108 EPAAAPAPTKEEVL 121
                  P  ++ +
Sbjct: 145 IKPTVRCPYCKQYI 158


>UniRef50_B8MJW8 Ion channel, putative n=3 Tax=Trichocomaceae RepID=B8MJW8_TALSN
          Length = 235

 Score = 93.5 bits (231), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 38/112 (33%), Positives = 56/112 (50%), Gaps = 17/112 (15%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL--------------- 48
              F +FAMR NV+++A+G++IG AF K+V+S V+D+I+P + LL               
Sbjct: 72  WDGFVDFAMRDNVLEVAIGLMIGQAFTKVVTSFVSDVILPVISLLPFIHRNLDEKFSVLR 131

Query: 49  -IGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI 99
                D      TL  A+ D  A+VM YG F+ NV  FL V   ++      
Sbjct: 132 KGPNYDLAGGYNTLAQARDD-GALVMAYGAFLNNVMSFLGVGIVLYGLAHFY 182


>UniRef50_C9RJE4 Large conductance mechanosensitive channel protein n=1
           Tax=Fibrobacter succinogenes subsp. succinogenes S85
           RepID=C9RJE4_FIBSS
          Length = 149

 Score = 93.1 bits (230), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 67/143 (46%), Positives = 93/143 (65%), Gaps = 14/143 (9%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI---GGIDFKQFA 58
           S+I+EF+ FA +GN+VD+A+G+IIGAAFGKIV+S V DI+MP +  +I   GG +  +  
Sbjct: 9   SLIEEFKAFAFKGNIVDMAIGIIIGAAFGKIVNSFVNDIVMPLVTAVIAKCGGQNAGEGI 68

Query: 59  VTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIK----LINKLNRKK-----EEP 109
            TL     +   + + YG FI  V +FLIVAFA+F+ +K     +  + +KK       P
Sbjct: 69  KTLVYTTSE--GIAIPYGTFIGEVLNFLIVAFAVFLMMKKFLGFMQNMRKKKEAEAAAAP 126

Query: 110 AAAPAPTKEEVLLTEIRDLLKEQ 132
           AA PAP+ EE LLTEIRDLLK +
Sbjct: 127 AAPPAPSAEEKLLTEIRDLLKNK 149


>UniRef50_A6GYI6 Large-conductance mechanosensitive channel n=4
           Tax=Flavobacteriaceae RepID=MSCL_FLAPJ
          Length = 138

 Score = 93.1 bits (230), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 55/138 (39%), Positives = 80/138 (57%), Gaps = 7/138 (5%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M    +F+   M+G+V+ LA  V+IG AFGKIV S V DIIMP +G+L GG+DF    + 
Sbjct: 1   MGFFADFKASLMKGDVLSLATAVVIGGAFGKIVGSAVDDIIMPIVGVLTGGVDFTTKFIA 60

Query: 61  LRDAQ-------GDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
           L               A  + YG  +Q + +F+I++F IF+ ++   K  +K+E    AP
Sbjct: 61  LNGQSYADLAAAKTAGAACLTYGNLVQAIINFIIISFFIFVVLRAAEKAKKKEEAAPTAP 120

Query: 114 APTKEEVLLTEIRDLLKE 131
           A   +E LLT+IRDLLK+
Sbjct: 121 AGPSQEELLTQIRDLLKK 138


>UniRef50_Q2NK99 Large-conductance mechanosensitive channel n=2 Tax=Candidatus
           Phytoplasma asteris RepID=Q2NK99_AYWBP
          Length = 145

 Score = 93.1 bits (230), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 50/140 (35%), Positives = 74/140 (52%), Gaps = 13/140 (9%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG-GIDFKQFAV 59
           +   K F+ F  RGNV++LAV V+IG  F KIVSSLVADIIMP   LL       K    
Sbjct: 12  LEFAKGFKAFIARGNVINLAVAVVIGQLFAKIVSSLVADIIMPLFSLLFNYTGALKDLKF 71

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAA------P 113
           T++          + YG F+Q + +FL+++F I+  + L++  N  ++E           
Sbjct: 72  TIK------ANTYLCYGNFLQTILEFLLLSFIIYTILTLMSWKNPLQKEKTDKNMLLLQQ 125

Query: 114 APTKEEVLLTEIRDLLKEQN 133
           +  KE  LL EI+++LK   
Sbjct: 126 SLNKEIALLEEIKNILKSNK 145


>UniRef50_A1SES5 Large-conductance mechanosensitive channel n=1 Tax=Nocardioides sp.
           JS614 RepID=A1SES5_NOCSJ
          Length = 129

 Score = 91.9 bits (227), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 37/133 (27%), Positives = 61/133 (45%), Gaps = 12/133 (9%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  F+ F +RGN+V+LAV   + AA    V +    +IM  +G   G  DF  +      
Sbjct: 1   MTGFKNFILRGNLVELAV-AFVMAAAFATVVTATVGLIMDLIGKAGGTPDFSDYVWN--- 56

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLT 123
                    +  G ++  +  FLI+A  ++  I +     +++  P+  P   ++  LL 
Sbjct: 57  --------GISIGAWLTALISFLIIAAVVYFFIVVPYTKAKERYFPSPEPGTPEDVKLLE 108

Query: 124 EIRDLLKEQNNRS 136
           EIRDLL  Q  RS
Sbjct: 109 EIRDLLATQQGRS 121


>UniRef50_C7QC56 Large conductance mechanosensitive channel protein n=1
           Tax=Catenulispora acidiphila DSM 44928
           RepID=C7QC56_CATAD
          Length = 174

 Score = 91.9 bits (227), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 40/126 (31%), Positives = 58/126 (46%), Gaps = 10/126 (7%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGI-DFKQFAVTLR 62
           +  F +F +RGNV+ LAVGV+IGAAF  +V+S     + P +G   GGI D+ +   TL 
Sbjct: 1   MNGFVKFVVRGNVIGLAVGVVIGAAFAAMVTSFTTAFLTPLIGWATGGIGDYSKKVFTLG 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI-NKLNRKKEEPAA-APAPTKEEV 120
                       YG F+     FL+ A  ++  I L  NKL  +       + A      
Sbjct: 61  K-------TPFPYGTFVNAGISFLLTAATLYFLIVLPVNKLTEELNPHHDLSHAKRSCPE 113

Query: 121 LLTEIR 126
            L +I 
Sbjct: 114 CLQQIP 119


>UniRef50_UPI0001B45932 large conductance mechanosensitive channel n=1 Tax=Mycobacterium
           intracellulare ATCC 13950 RepID=UPI0001B45932
          Length = 139

 Score = 91.5 bits (226), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 28/132 (21%), Positives = 58/132 (43%), Gaps = 6/132 (4%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +IK F+ F MRG+V+ +A+G+++  AF  +V +    +I P +  +  G  F    +  +
Sbjct: 1   MIKGFKSFVMRGDVITVAIGLVVALAFSNLVKAFTDSVINPLVAAVQPGTKF---GLGWQ 57

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA---AAPAPTKEE 119
                  A  +  G FI  +  F++   A++  I +  K  + +         PA     
Sbjct: 58  LGDAGNKATFLDIGSFISAIIYFVVFMTAVYFMIVVPYKHIQARRGVTVFGEEPATKACA 117

Query: 120 VLLTEIRDLLKE 131
              ++I +  ++
Sbjct: 118 ECKSDIPEAARK 129


>UniRef50_B1XK85 Large conductance mechanosensitive channel protein n=3 Tax=Bacteria
           RepID=B1XK85_SYNP2
          Length = 145

 Score = 90.8 bits (224), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 46/104 (44%), Positives = 66/104 (63%), Gaps = 7/104 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           S   +F+ F MRGNV+DLAV V+IG AFG+IV+SLVADII P +            +   
Sbjct: 6   SFWSDFQAFIMRGNVIDLAVAVVIGGAFGQIVNSLVADIITPAI-------LQPALSAAN 58

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRK 105
            DA G++    + YG+F+  V +FL++AFAIF+ I+ I K+ R+
Sbjct: 59  LDALGELSFNGIKYGLFLAAVINFLVIAFAIFLVIRAIEKMQRR 102


>UniRef50_B8MKR4 Large-conductance mechanosensitive channel, putative n=1
           Tax=Talaromyces stipitatus ATCC 10500 RepID=B8MKR4_TALSN
          Length = 288

 Score = 88.1 bits (217), Expect = 9e-17,   Method: Composition-based stats.
 Identities = 30/131 (22%), Positives = 56/131 (42%), Gaps = 17/131 (12%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-------------- 49
              F +FA+R NV+++A+G+II AAF K+V+S V+D+ +P + LL               
Sbjct: 23  WDGFWDFALRDNVLEVAIGLIIAAAFTKVVNSFVSDLFLPIISLLPFLNRNLEDKFAVLR 82

Query: 50  GGIDFKQF---AVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK 106
            G  +  +        +   D  A+VM YG F+    +F+ +   ++   ++    +   
Sbjct: 83  KGKHYSDWGPGGYNTLEQARDDGALVMAYGAFLDKFINFVGIGLTLYTVGQVYTWFSDDV 142

Query: 107 EEPAAAPAPTK 117
                      
Sbjct: 143 VIKRTVKCRYC 153


>UniRef50_Q83MR6 Large-conductance mechanosensitive channel n=2 Tax=Tropheryma
           whipplei RepID=Q83MR6_TROWT
          Length = 207

 Score = 85.8 bits (211), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 1/97 (1%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           +   FR+F  R NVVDL+  V+IGAA   +++++V DI  P +   +     +  ++ L 
Sbjct: 5   MFAGFRDFIARRNVVDLSAAVVIGAASTAVINAIVDDIFSPLISAALSSSKIEN-SLVLT 63

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLI 99
                   V + +G  +  +  F++V+  ++  I L 
Sbjct: 64  IPTLSHGHVQLKFGTVLLALIKFVLVSAVVYFVIILP 100


>UniRef50_Q98B35 Large-conductance mechanosensitive channel n=1 Tax=Mesorhizobium
          loti RepID=Q98B35_RHILO
          Length = 87

 Score = 85.0 bits (209), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 38/61 (62%), Positives = 48/61 (78%)

Query: 3  IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
          ++KEF+EF  +GNV+DLAVGVIIGAAFGKIV SLV DIIMP +G + GG+DF  + + L 
Sbjct: 1  MLKEFQEFISKGNVMDLAVGVIIGAAFGKIVDSLVNDIIMPIVGAIFGGLDFNNYFLGLP 60

Query: 63 D 63
           
Sbjct: 61 Q 61


>UniRef50_A4RKI5 Putative uncharacterized protein n=1 Tax=Magnaporthe grisea
           RepID=A4RKI5_MAGGR
          Length = 175

 Score = 84.6 bits (208), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 22/140 (15%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI------------- 49
           +   F +FA++GN++++A G+I+ AAF  I++SLV+DI++PPL +L              
Sbjct: 32  VWDGFLDFALQGNILEIAFGLILAAAFTSIINSLVSDILLPPLSVLFPLNKNLDEKFAVL 91

Query: 50  -GGIDFK--QFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKK 106
             G +F              +  AVVM +G F+  V +FL +  +++    L    +  +
Sbjct: 92  KPGPNFDPANGGYPTIQLAQEDSAVVMAWGSFVNKVLNFLGLGVSLYALAGLYQYFSNGR 151

Query: 107 EEPAAAPAPTKEEVLLTEIR 126
              +   A       L E+R
Sbjct: 152 SAASTVQAG------LMELR 165


>UniRef50_Q5HPJ2 Large-conductance mechanosensitive channel n=9 Tax=Bacteria
           RepID=MSCL_STAEQ
          Length = 116

 Score = 84.6 bits (208), Expect = 8e-16,   Method: Composition-based stats.
 Identities = 60/129 (46%), Positives = 88/129 (68%), Gaps = 13/129 (10%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++KEF+EFA++GNV+DLA+ V++GAAF KIV+SLV  IIMP +G L G ++F        
Sbjct: 1   MLKEFKEFALKGNVLDLAIAVVMGAAFNKIVTSLVQYIIMPLIGKLFGSVNF-------- 52

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLL 122
               D     + YG+FIQ++ DF+I+AFA+F+ +K+ N + +K+E+       T   VLL
Sbjct: 53  --AEDWSFWGIKYGLFIQSIIDFIIIAFALFIFVKIANTVMKKEEKEEEVEENT---VLL 107

Query: 123 TEIRDLLKE 131
           TEIRDLLK+
Sbjct: 108 TEIRDLLKK 116


>UniRef50_B3PMZ4 Large-conductance mechanosensitive channel, putative n=2
           Tax=Mycoplasma RepID=B3PMZ4_MYCA5
          Length = 152

 Score = 83.4 bits (205), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 40/133 (30%), Positives = 63/133 (47%), Gaps = 19/133 (14%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
           K+ ++   +GN+  LA+ V+IGAAFG +VSSL  D+IM  +  +      +   V     
Sbjct: 18  KDAKKSITKGNMFMLAIAVLIGAAFGAVVSSLANDVIMAAIAKIWNASSVEDLKV----- 72

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAI---------KLINKLNRKKEEPAAAPAP 115
                A  +  G F+  +  F+IVA  +F  +             K  +   EP A P P
Sbjct: 73  -----AGTIKIGKFLAALIQFVIVATVVFFTLLIVFSIKNAIEYAKAKKMPIEPEAEPTP 127

Query: 116 TKEEVLLTEIRDL 128
           T EE++L E++ L
Sbjct: 128 TNEELILAELKKL 140


>UniRef50_B2VVD2 Putative uncharacterized protein n=1 Tax=Pyrenophora
           tritici-repentis Pt-1C-BFP RepID=B2VVD2_PYRTR
          Length = 242

 Score = 83.4 bits (205), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 35/119 (29%), Positives = 58/119 (48%), Gaps = 17/119 (14%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL-IGGIDFKQFAVT 60
           S  + F  FA+R NV+++AVG+I+ ++F    ++LV+DII+P + LL           V 
Sbjct: 25  SAWESFSNFALRDNVLEVAVGLILASSFTACANALVSDIILPIISLLPFLSRTLDTKFVL 84

Query: 61  LRDAQG----------------DIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN 103
           LR                    D  AVV+ YG F+  +  F IVA A+++   +  + +
Sbjct: 85  LRHGPNSNSTISAGYNTPAQAVDDGAVVLAYGHFLDKIVRFAIVALALWVIANVYGRFS 143


>UniRef50_D2S4B1 Large conductance mechanosensitive channel protein n=1
           Tax=Geodermatophilus obscurus DSM 43160
           RepID=D2S4B1_9ACTO
          Length = 136

 Score = 82.3 bits (202), Expect = 5e-15,   Method: Composition-based stats.
 Identities = 35/110 (31%), Positives = 60/110 (54%), Gaps = 7/110 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           +++  FR FA  G++VDLAVG+ IGAAF  +V SLV D+I+P +  + G  +F    +T 
Sbjct: 3   TLLTNFRNFAFSGSLVDLAVGLAIGAAFAAVVESLVGDVILPLVAAIFGAPNFDVLVLT- 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAA 111
                 +    + YG F+  +  FL++A  I + ++ I +   ++   A 
Sbjct: 62  ------VNGAQIRYGSFLTALVSFLLLALTIMLLVQAIRRATGRETAGAQ 105


>UniRef50_D2ARQ8 Large conductance mechanosensitive channel protein n=9 Tax=Bacteria
           RepID=D2ARQ8_STRRD
          Length = 142

 Score = 81.1 bits (199), Expect = 9e-15,   Method: Composition-based stats.
 Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 9/125 (7%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI--GGIDFKQFAVTL 61
           +  F++F MRGN+V+LAV V++GA F  +V +LV D+I P +  +   GG DF Q+  T+
Sbjct: 1   MGGFKKFLMRGNLVELAVAVVVGATFSGLVQALVKDLITPLIAAITGGGGPDFSQYVFTV 60

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
             A+         YG FI ++  FLI+A  I+  + +         +        +    
Sbjct: 61  NGAK-------FMYGDFINHLLSFLIIAAVIYWLVVMPMTRVIAFFDRDKKATEKECPEC 113

Query: 122 LTEIR 126
           L++I 
Sbjct: 114 LSDIP 118


>UniRef50_B3QZY1 Large-conductance mechanosensitive channel n=1 Tax=Candidatus
           Phytoplasma mali AT RepID=B3QZY1_PHYMT
          Length = 139

 Score = 81.1 bits (199), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 35/119 (29%), Positives = 65/119 (54%), Gaps = 6/119 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGG--IDFKQFAV 59
           +  K F++F  +GNV++L++  +I   F KIV+SL +DIIMP + LL      DF     
Sbjct: 10  NFTKGFKKFINKGNVLNLSIAFVISQLFSKIVNSLSSDIIMPFMNLLFSSDKNDFSDLRF 69

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE 118
            +         + ++YG F++ VF+FLI++F I++ + ++ + N   E+        ++
Sbjct: 70  RIT----SNSNIYIYYGKFLKTVFEFLIMSFFIYIILIIVFRQNLNSEKVNIESLTKEQ 124


>UniRef50_A5GNA8 Large-conductance mechanosensitive channel n=1 Tax=Synechococcus
           sp. WH 7803 RepID=A5GNA8_SYNPW
          Length = 117

 Score = 81.1 bits (199), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 31/105 (29%), Positives = 56/105 (53%), Gaps = 8/105 (7%)

Query: 4   IKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           ++EF EF   +GN ++LA+ V++G  F +IV+++  D++MP L  L+ G +++   +   
Sbjct: 1   MREFTEFFFQKGNALNLAIAVVVGTQFQQIVNAISKDLLMPLLNPLVRGGNWQNLVIPYY 60

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKE 107
                     +  G     + + LIV +A+F  IK IN+  R  E
Sbjct: 61  GGD-------LAIGKIFDVILNSLIVGWALFFIIKAINRSQRTLE 98


>UniRef50_A8N9V8 Putative uncharacterized protein n=1 Tax=Coprinopsis cinerea
           okayama7#130 RepID=A8N9V8_COPC7
          Length = 209

 Score = 80.7 bits (198), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 33/161 (20%), Positives = 58/161 (36%), Gaps = 34/161 (21%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLL-IGGIDFKQFAVT 60
            +   F  F +R NV+++AVG+I   AF K+V+SLV++II+PP+ LL     +  +  + 
Sbjct: 34  GLWGGFTAFVLRDNVLEVAVGLIFATAFTKLVTSLVSNIILPPISLLPFMSKNLDEKFLV 93

Query: 61  LRDAQ--------------GDIPAVVMHYG-----------VFIQNVFDFLIVAFAIFMA 95
           L+                     A+V  YG            F      F+ V  A+++ 
Sbjct: 94  LKKGPNFEPPNGYNTREQASGDGAIVWAYGVSCERDVVHDRAFADEALKFIGVGAALYLI 153

Query: 96  IKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS 136
             +     +                     R  +  +  R 
Sbjct: 154 ATVYGAFTKDSIIRDTIRC--------MYCRKEISAKAKRC 186


>UniRef50_Q0I7U4 Large-conductive mechanosensitive channel n=2 Tax=Synechococcus
           RepID=Q0I7U4_SYNS3
          Length = 157

 Score = 79.6 bits (195), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 27/103 (26%), Positives = 55/103 (53%), Gaps = 8/103 (7%)

Query: 3   IIKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
             +EF +F   +GN ++LA+ V++G  F ++V +L  D++MP L  LI    ++++ +  
Sbjct: 43  WFREFTDFFFQKGNALNLAIAVVVGTQFQQVVDALTQDLLMPLLNPLIRNGGWEEWVLPY 102

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
              +       +  G  +  + + LIV + +F+ +K IN+  R
Sbjct: 103 AGGE-------LLLGKAMNVLLNSLIVGWVLFLIVKAINRSQR 138


>UniRef50_A7HBZ5 Large conductance mechanosensitive channel protein n=1
           Tax=Anaeromyxobacter sp. Fw109-5 RepID=A7HBZ5_ANADF
          Length = 139

 Score = 79.6 bits (195), Expect = 3e-14,   Method: Composition-based stats.
 Identities = 41/113 (36%), Positives = 62/113 (54%), Gaps = 7/113 (6%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            + KEFREF ++ NV+ LA GV+IGAA GK+VS +V  ++MP +GLL+ G D        
Sbjct: 13  GLAKEFREFLLKQNVIALAAGVVIGAAIGKVVSGIVDFVVMPVVGLLLPGQD------EW 66

Query: 62  RDAQGDIPAV-VMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
           R A+ DI     + YG  +  + +F I+A  +F+ +K   +         A P
Sbjct: 67  RQAKLDIGGGNAIGYGEVVGRLVEFGIIALVVFLVLKAFVRAPPPPAPTKACP 119


>UniRef50_Q0CER3 Putative uncharacterized protein n=3 Tax=Aspergillus
            RepID=Q0CER3_ASPTN
          Length = 1384

 Score = 78.1 bits (191), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 37/151 (24%)

Query: 4    IKEFREFAMRGNVVDLAVGVI--------------------IGAAFGKIVSSLVADIIMP 43
             + F  FA R NV+++A+G++                    I  AF K+V+S V+DII+P
Sbjct: 1214 WEGFVNFAARDNVLEVALGLMYLPPLPSLPPLPPVPLTQCSIAQAFTKVVTSFVSDIILP 1273

Query: 44   PLGL--------------LIGGIDF--KQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLI 87
             + L              L+ G  +   +   TL  A+ D  A+V+ YGVF++ V  FL 
Sbjct: 1274 IISLLPFLNRNMDQKFAVLMAGPRYVEGEGYNTLTQARDD-GALVLAYGVFLETVLSFLG 1332

Query: 88   VAFAIFMAIKLINKLNRKKEEPAAAPAPTKE 118
            V+  ++   KL   ++              +
Sbjct: 1333 VSVTLYAVAKLYMYISHDAIIKPTVHCRYCK 1363


>UniRef50_D1YYF3 Putative large-conductance mechanosensitive channel n=1
           Tax=Methanocella paludicola SANAE RepID=D1YYF3_METPS
          Length = 101

 Score = 78.1 bits (191), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 36/108 (33%), Positives = 59/108 (54%), Gaps = 7/108 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M I+++F+EF     V+ LAV  I+G A   ++ +LV DIIMP +G LI G         
Sbjct: 1   MGIMQDFKEFLNEYKVMGLAVAFIMGVAATALIQALVNDIIMPIIGRLIPGG-------A 53

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
            + A  DI  ++  +G F+  V +F+I+AF +F+  K I    +  ++
Sbjct: 54  WQTATLDIAGMLFKWGDFLSQVINFVIIAFVVFLIAKFIMGEKKVTKK 101


>UniRef50_Q0IDN4 Large conductance mechanosensitive channel protein n=2
           Tax=Synechococcus RepID=Q0IDN4_SYNS3
          Length = 127

 Score = 77.3 bits (189), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 17/135 (12%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
            +  +F+ F  +GNVVDLA+ V+I  AFGK+V+++V  ++   L   +   +        
Sbjct: 6   GLFADFKAFINKGNVVDLAIAVVIAGAFGKVVATVVTLVMTNALEPALKAANVDSI---- 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                         G  I  + +FL++AF  F+ +K I   +++K+E  A   P  +  L
Sbjct: 62  ---------NSWPAGTVIVAIINFLVIAFVCFLIVKSIE-ASKRKQEVIAETKPDPQAQL 111

Query: 122 ---LTEIRDLLKEQN 133
              +T + D L+ + 
Sbjct: 112 ASAMTRLTDALERKG 126


>UniRef50_A7I494 Large-conductance mechanosensitive channel-like protein n=3
           Tax=Genera incertae sedis RepID=A7I494_METB6
          Length = 125

 Score = 76.1 bits (186), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 33/101 (32%), Positives = 51/101 (50%), Gaps = 7/101 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M   +EF  F  +  V+ LAV  +IG A   +V++LV DIIMP + +L  G         
Sbjct: 25  MGFKEEFLLFLKQYQVIGLAVAFVIGTAATAMVNALVKDIIMPVVSVLTPGG-------Q 77

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINK 101
            + A   +  + +  G F+  V DFLI+A  +F  +K + K
Sbjct: 78  WQTAVLAVGPINLLAGDFLSAVLDFLIIALVVFFLVKYVMK 118


>UniRef50_C7PYG5 Large conductance mechanosensitive channel protein n=1
           Tax=Catenulispora acidiphila DSM 44928
           RepID=C7PYG5_CATAD
          Length = 145

 Score = 75.7 bits (185), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 38/128 (29%), Positives = 55/128 (42%), Gaps = 7/128 (5%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  FR+F +RGN+VDLAV V++G+ F  +V   VA  I P LG +    +F   + T+R 
Sbjct: 1   MSGFRKFILRGNLVDLAVAVVVGSLFSSLVKQFVASFITPLLGTIGATPNFDHLSFTIRR 60

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLT 123
                      YG F+   F F+I A  ++ AI L         +   A           
Sbjct: 61  HA-------FAYGAFLTEAFSFVIAAIVMYFAIVLPFSRMIHLFDGNQAATEKDCPACTM 113

Query: 124 EIRDLLKE 131
            I  L K 
Sbjct: 114 RIPVLAKR 121


>UniRef50_D0P2C6 Large conductance mechanosensitive channel, putative n=2
           Tax=Phytophthora infestans T30-4 RepID=D0P2C6_PHYIN
          Length = 158

 Score = 75.7 bits (185), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 31/120 (25%), Positives = 62/120 (51%), Gaps = 7/120 (5%)

Query: 2   SIIKEFREFAMRGNVVDLAVGV--IIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAV 59
           +++ +F++F  +GN++D+A G    I  ++G     LVA + +  LG  +     K F +
Sbjct: 14  ALLTDFQDFIQQGNMIDMATGASPTITGSYGAQQLPLVAQVRLGRLGNKVPDNKMKAFVL 73

Query: 60  TLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEE 119
            ++D       V ++YG+F++N   F I A  +F+A+K + ++  K+        P  +E
Sbjct: 74  LVKDGV-----VTINYGLFMENAVTFFINAIFLFLAVKKVFEVVFKRSVLVKKQCPHCKE 128


>UniRef50_A3Z5P9 Possible large-conductance mechanosensitive channel mscL n=1
           Tax=Synechococcus sp. RS9917 RepID=A3Z5P9_9SYNE
          Length = 102

 Score = 75.0 bits (183), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 29/103 (28%), Positives = 53/103 (51%), Gaps = 13/103 (12%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           +   +F++F  +GNVVDLAV V+IG AFGK+V ++V+ ++   L  ++   +        
Sbjct: 6   TFFADFKDFINKGNVVDLAVAVVIGGAFGKVVDAVVSLVMGNILEPVLKAANVDSI---- 61

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
                         G  I  + +FL++AF +F+ ++ I  + R
Sbjct: 62  ---------AAWPAGSVIVALINFLVIAFVVFLIVRAIEAMRR 95


>UniRef50_Q6KH26 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           mobile RepID=Q6KH26_MYCMO
          Length = 151

 Score = 73.8 bits (180), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 16/139 (11%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
            E +    RGN++ LAVG+++G  FG +V+S   DI++  +G+ I  +            
Sbjct: 18  DEAKSALKRGNILMLAVGLLLGTVFGALVASFANDILLGAIGIGINALGININNF----- 72

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIV------AFAIFMAIKLINKLNRKKEEPA----AAPA 114
             D+    + YG FI  +  F+IV      A  I+  I+ I   N KK+ P     AAP 
Sbjct: 73  -SDLSFQTIRYGNFISALLTFIIVSLFIFFALFIYFVIRNIRLDNLKKKYPERYVVAAPK 131

Query: 115 PTKEEVLLTEIRDLLKEQN 133
           P+ +E++L E+R L + + 
Sbjct: 132 PSTDELILEELRTLNRAKR 150


>UniRef50_Q2FQE0 Large conductance mechanosensitive channel protein n=4
           Tax=Euryarchaeota RepID=Q2FQE0_METHJ
          Length = 108

 Score = 72.3 bits (176), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 7/108 (6%)

Query: 1   MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVT 60
           M++I EF +F     VV LA+  I+G A   +V S V ++IMP + ++    D       
Sbjct: 8   MTLISEFLDFLKEYKVVALAIAFIMGVAATALVKSFVDNLIMPFVSVITPSGD------- 60

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEE 108
            ++A   I  V +  G F     +F+I+A  +FM  K + K  + +++
Sbjct: 61  WKEAVLAIGPVQLGIGPFAAECINFIIIALVVFMVAKYVMKEEKVEKK 108


>UniRef50_C1MQL7 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MQL7_9CHLO
          Length = 218

 Score = 72.3 bits (176), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 20/108 (18%), Positives = 41/108 (37%), Gaps = 7/108 (6%)

Query: 10  FAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIP 69
           F      V +AVG++ G+A  ++V +    ++ P +  + G                 + 
Sbjct: 82  FITSSQAVPVAVGLVFGSALRQLVDAFTTALVAPLVASVGGHSHLVSLRFV-------VH 134

Query: 70  AVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTK 117
            +   YGVF+Q V +  +   A+F  + + +   +        P P  
Sbjct: 135 GLAFDYGVFVQAVLETFLTIVALFYLVVVPSSAVKSLRLSPTRPCPEC 182


>UniRef50_Q3AHC1 Large-conductive mechanosensitive channel n=1 Tax=Synechococcus sp.
           CC9605 RepID=Q3AHC1_SYNSC
          Length = 109

 Score = 71.1 bits (173), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 27/112 (24%), Positives = 50/112 (44%), Gaps = 8/112 (7%)

Query: 3   IIKEFREFAM-RGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           ++KEF +F   +GNV+ LA+ V++G     I  SL  D++MP +   I    +K  A+  
Sbjct: 4   LLKEFTDFFFTKGNVLALAIAVVVGDQVSAITKSLSTDLLMPLINPFIPHGSYKDLAIPY 63

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAP 113
                      +  G  +      ++VA+A+F+ I+   +  R  +      
Sbjct: 64  FGGP-------IAIGKVLDTFVSAMLVAWALFIIIQATKRFERISQRDNIPA 108


>UniRef50_C5BF23 Putative uncharacterized protein n=1 Tax=Edwardsiella ictaluri
           93-146 RepID=C5BF23_EDWI9
          Length = 77

 Score = 70.7 bits (172), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 45/72 (62%), Positives = 53/72 (73%), Gaps = 1/72 (1%)

Query: 61  LRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEV 120
           +R A G  PA+V +YG FIQ +FDF+IV FAIFMAIK INKL R+K      PAP+ E V
Sbjct: 1   MRKAIGSTPALVANYGQFIQAIFDFIIVTFAIFMAIKPINKLRRQKTA-ETPPAPSAEAV 59

Query: 121 LLTEIRDLLKEQ 132
           LLTEIR+LLK Q
Sbjct: 60  LLTEIRELLKAQ 71


>UniRef50_D1J7K2 Large-conductance mechanosensitive channel n=1 Tax=Mycoplasma
           hominis ATCC 23114 RepID=D1J7K2_MYCHP
          Length = 172

 Score = 70.3 bits (171), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 38/134 (28%), Positives = 65/134 (48%), Gaps = 12/134 (8%)

Query: 6   EFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQ 65
           + ++   RGN+  LA+G+++GA+FG +VSSL  D+IM  +   +G  +   + V      
Sbjct: 19  DAKKIVSRGNMFMLAIGLLLGASFGALVSSLANDVIMSAITKAVGMKNLDAW-VVWPGIH 77

Query: 66  GDIPAVVMHYGVFIQNVFDFLIVAFAIFM-----------AIKLINKLNRKKEEPAAAPA 114
                  +  G F+  +  F+IV+  IF+            +    K N  +EE    P 
Sbjct: 78  ATKETGGIFIGKFLGALIQFIIVSTFIFIGLMIVFTIKNSILYAKAKKNPIEEEIKEEPI 137

Query: 115 PTKEEVLLTEIRDL 128
           PT EE++L E++ L
Sbjct: 138 PTTEELILNELKKL 151


>UniRef50_A5IYZ8 Large conductance mechanosensitive channel n=1 Tax=Mycoplasma
           agalactiae PG2 RepID=A5IYZ8_MYCAP
          Length = 140

 Score = 69.2 bits (168), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 19/126 (15%)

Query: 11  AMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPA 70
             RGN++ LA+GV+IGA+F  ++SSL  D+IM  +  L       +             A
Sbjct: 13  VKRGNMLLLAIGVLIGASFNAVISSLANDVIMAAIASLFNVQAVSELK-----------A 61

Query: 71  VVMHYGVFIQNVFDFLIVAFAIFMAIKLI--------NKLNRKKEEPAAAPAPTKEEVLL 122
             +  G F+  +  F+IVA  IF+ + L          +  +K        APT +E++L
Sbjct: 62  GPVLIGKFLAALISFIIVALIIFLFLILYFLIKNAVEARKAKKNPPVVVVAAPTTDELIL 121

Query: 123 TEIRDL 128
            E++ L
Sbjct: 122 QELKKL 127


>UniRef50_Q0UYA9 Putative uncharacterized protein n=1 Tax=Phaeosphaeria nodorum
           RepID=Q0UYA9_PHANO
          Length = 164

 Score = 69.2 bits (168), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 11/109 (10%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
              F  FA+R NV+++AVG+I          +L     +   G    G        T++ 
Sbjct: 60  WDSFSNFALRDNVLEVAVGLI---------RNLDEKFAILKHGPHYNGT-ITNGYNTVKQ 109

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAA 112
           A  D  AVV  YG F+  V  F+ +A  +++     ++ +         
Sbjct: 110 ALDD-GAVVFAYGSFLDKVVRFVCIALTLWIIAIAYSRGSGDNIVKKQV 157


>UniRef50_A5Z9U3 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
           ATCC 27560 RepID=A5Z9U3_9FIRM
          Length = 101

 Score = 68.4 bits (166), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 9/91 (9%)

Query: 42  MPPLGLLIGGIDFKQFAVTLRDA-------QGDIPAVVMHYGVFIQNVFDFLIVAFAIFM 94
           MP + LL G IDF    + L               A  ++YG FI  + +FLI+AF +FM
Sbjct: 1   MPVITLLTGKIDFSNLFIALDGGSYKTLAEAQKAGAATLNYGTFISGLINFLIMAFVVFM 60

Query: 95  AIKLINKLNRKKEEPAAAPAPTKEEVLLTEI 125
            +K +NKL RK+E   A           +E+
Sbjct: 61  IVKFMNKLRRKEE--PAPATTKICPHCKSEV 89


>UniRef50_A5KRR6 Large-conductance mechanosensitive channel-like protein n=1
           Tax=candidate division TM7 genomosp. GTL1
           RepID=A5KRR6_9BACT
          Length = 119

 Score = 68.0 bits (165), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 29/85 (34%), Positives = 48/85 (56%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
            +F  F     V  LAVG+++G A   +V SL+ +I+MPPLGL++G  +  +        
Sbjct: 16  SDFMTFIREQGVAGLAVGLVLGGAVTVVVKSLIDNIVMPPLGLVLGSAEGLKGLSLSLGQ 75

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVA 89
                  V+HYGVF+ +V +F+++A
Sbjct: 76  TAAGKDAVLHYGVFLNDVVNFMVIA 100


>UniRef50_B1MYM2 Large-conductance mechanosensitive channel n=1 Tax=Leuconostoc
           citreum KM20 RepID=B1MYM2_LEUCK
          Length = 158

 Score = 66.1 bits (160), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 21/97 (21%), Positives = 42/97 (43%), Gaps = 8/97 (8%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
             +F++F    N++   + V++G +FG  V  LV  +         G + F    +  + 
Sbjct: 23  FGQFKQFLFAPNLLTFVISVVVGNSFGATVKELVNTV--------SGVLAFVHLWLFSKS 74

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLIN 100
              +   +   +G F  ++   + +AF +F  IK IN
Sbjct: 75  HVMNYTFITKPFGSFFNSLITMIFIAFIVFYTIKFIN 111


>UniRef50_Q6SZN0 Putative uncharacterized protein (Fragment) n=1 Tax=Rhodococcus
           fascians RepID=Q6SZN0_RHOFA
          Length = 125

 Score = 65.7 bits (159), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 25/111 (22%), Positives = 49/111 (44%), Gaps = 4/111 (3%)

Query: 21  VGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQ 80
           V +++GAAF  IV++  ++II P +  + G  +        ++     P   ++ G  + 
Sbjct: 3   VAIVVGAAFTAIVTAFTSNIINPLIAAIGGSDELGWG----KEIIAGNPXTFVNIGAVVT 58

Query: 81  NVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKE 131
            +  F+I+A   +  + +     +KK           E  LL +IRD+L  
Sbjct: 59  AIIXFVIIAVVXYFVLIVPANAAKKKFITEPEDKEASETDLLIQIRDILAS 109


>UniRef50_C9S828 Putative uncharacterized protein n=1 Tax=Verticillium albo-atrum
           VaMs.102 RepID=C9S828_VERA1
          Length = 129

 Score = 65.7 bits (159), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 32/92 (34%), Positives = 51/92 (55%), Gaps = 17/92 (18%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI------------- 49
           +   F +FAM+GN++++A G+I+ AAF  +V+S VA+I+MPPL ++              
Sbjct: 26  LWSGFIDFAMQGNILEIAFGLILAAAFTGLVNSFVANILMPPLSVIFPLNHNMEEKFAVL 85

Query: 50  -GGIDF--KQFAVTLRDAQGDIPAVVMHYGVF 78
             G D+  +    TL  A+ D  AVV+ YG  
Sbjct: 86  KPGPDYNREDGYTTLARAKDD-GAVVLAYGSV 116


>UniRef50_UPI00017434B6 large conductance mechanosensitive channel protein n=1
          Tax=candidate division TM7 single-cell isolate TM7a
          RepID=UPI00017434B6
          Length = 79

 Score = 64.6 bits (156), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)

Query: 3  IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
          + KE R +  R      + G    + FGKIV+SLV DIIMP +G+++G IDF    + + 
Sbjct: 1  MFKELRNYIKRKCDGSCSWGYNW-SRFGKIVTSLVDDIIMPVIGIILGKIDFSNLKLVIT 59

Query: 63 DAQGDIPAVVMH 74
           A G  P   ++
Sbjct: 60 PASGSTPEAAVN 71


>UniRef50_C1DYF1 Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1DYF1_9CHLO
          Length = 187

 Score = 64.6 bits (156), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 18/115 (15%), Positives = 42/115 (36%), Gaps = 7/115 (6%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62
           + ++   F +    V +AVG + G+     V + V+  + P +  +      +    T  
Sbjct: 51  LFEQLNNFVLSSQAVPVAVGFVFGSCLKNNVDAFVSSFVAPSIAAIGSLQHLRDMHFT-- 108

Query: 63  DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTK 117
                +   +   GVF++++F+  I   A+F  I +   +    +          
Sbjct: 109 -----VNHSIFPVGVFVESMFETAITILALFYLIVVPMSMFTSLKYVPLRTCEEC 158


>UniRef50_B4WRC7 Large conductance mechanosensitive channel protein n=1
           Tax=Synechococcus sp. PCC 7335 RepID=B4WRC7_9SYNE
          Length = 142

 Score = 63.8 bits (154), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 45/127 (35%), Positives = 69/127 (54%), Gaps = 10/127 (7%)

Query: 3   IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMP-PLGLLIGGIDFKQFAVTL 61
              +F++F +RGNVV+LAV V++GAAF  IV+SLV DII P  L   +        A+  
Sbjct: 17  FANDFKQFLLRGNVVELAVAVVLGAAFNAIVTSLVQDIITPVLLQPALRSAGVDDIAL-- 74

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVL 121
                 + A  + YGVF+  V +F++V   +F+ ++   + +R +E  A  P PT  E L
Sbjct: 75  ------LSAGGVKYGVFLAAVINFIVVGLVLFLVVRTFARFSRTEEA-AIEPTPTPTEKL 127

Query: 122 LTEIRDL 128
              I+ L
Sbjct: 128 DITIQHL 134


>UniRef50_UPI00016B2696 Large-conductance mechanosensitive channel n=1 Tax=candidate
           division TM7 single-cell isolate TM7c
           RepID=UPI00016B2696
          Length = 156

 Score = 63.4 bits (153), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 4/106 (3%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +  F +F     V+ LAVG+ IG A G  V  LV   I P +  ++G  +  +      +
Sbjct: 53  LAGFMDFIREQGVIGLAVGLAIGTAAGDTVKKLVEGFISPIVQFIVGSKEGLEAVSLRVE 112

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKL--INKLNRKKE 107
             G +      +G F+ +    +  AF I++ I L  +NKL+++K+
Sbjct: 113 MLGRVAE--FKWGAFVSSAITLVATAFVIYLIINLAKLNKLDKEKK 156


>UniRef50_A7E8P9 Predicted protein n=1 Tax=Sclerotinia sclerotiorum 1980 UF-70
           RepID=A7E8P9_SCLS1
          Length = 231

 Score = 61.5 bits (148), Expect = 7e-09,   Method: Composition-based stats.
 Identities = 27/157 (17%), Positives = 51/157 (32%), Gaps = 49/157 (31%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVS--------------SLVADIIMPPLGL 47
           S    F +FA   NV+ +A+G+II  +F  +++                +   +     +
Sbjct: 30  SFWDGFVDFAFNDNVLHVAIGLIIAQSFTTLITSLVSSVLLPPLSLLPFLNKNLDEKFAV 89

Query: 48  LIGGIDFKQ----------------------------------FAVTLRDAQGDIPAVVM 73
           L  G  +                                       TL+ A  D  A+V+
Sbjct: 90  LRPGPHYGGTLHNHTEIGGGAGEGVEGNSTVVVQMGIEFLYGAGYNTLKQALDD-GAIVL 148

Query: 74  HYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA 110
            +G F+ NV +F+ V  A++    L    ++      
Sbjct: 149 AWGSFLNNVINFIGVGLALYGIAGLYQYFSQDNAIIK 185


>UniRef50_Q3D697 Large conductance mechanosensitive channel protein n=2
          Tax=Streptococcus agalactiae RepID=Q3D697_STRAG
          Length = 97

 Score = 61.1 bits (147), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 26/69 (37%), Positives = 40/69 (57%), Gaps = 1/69 (1%)

Query: 1  MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPL-GLLIGGIDFKQFAV 59
          + +IKE +EF  +GNV+DLAV VI+GAAF  I++SLV D+I P +   ++        A 
Sbjct: 21 VHMIKELKEFLFKGNVLDLAVAVILGAAFNAIITSLVKDVITPLILNPVLKAAGVSNIAQ 80

Query: 60 TLRDAQGDI 68
             +    +
Sbjct: 81 LSWNGVLTV 89


>UniRef50_Q2IFL2 Large-conductance mechanosensitive channel-like n=1
           Tax=Anaeromyxobacter dehalogenans 2CP-C
           RepID=Q2IFL2_ANADE
          Length = 137

 Score = 59.9 bits (144), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 32/96 (33%), Positives = 46/96 (47%), Gaps = 11/96 (11%)

Query: 46  GLLIGGIDFKQFAVTLRDAQGDIP----------AVVMHYGVFIQNVFDFLIVAFAIFMA 95
               GG DFK + V LR+    +P            V  YG F+    +FLI+AF +F+ 
Sbjct: 43  AARWGGFDFKDYFVALREIPPGVPRALDAMKKARVPVFAYGSFLTVALNFLILAFIVFLM 102

Query: 96  IKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKE 131
           +K  N+L R +  P     P +  VLL +IRD L+ 
Sbjct: 103 VKQFNRLRRAEPPPPPPAPPEE-VVLLRDIRDALRR 137


>UniRef50_Q7NAU3 MscL n=1 Tax=Mycoplasma gallisepticum RepID=Q7NAU3_MYCGA
          Length = 223

 Score = 59.6 bits (143), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 17/120 (14%)

Query: 4   IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63
           +K   +   RGN+  LA+G+++G +F  +++SL  D+I+  +  L    D +++ V    
Sbjct: 21  MKNATQVVKRGNIFMLAIGLLLGTSFNAVIASLANDVIIAAIAKLYNVQDLQKWQVQ--- 77

Query: 64  AQGDIPAVVMHYGVFIQNVFDFLIV------AFAIFMAIKLINKLNRKKEEPAAAPAPTK 117
                    +  G F   +  F+I+      A  +   I  + K  + K+  A    PT 
Sbjct: 78  --------GIFIGKFFAALLSFVIINVILVSALFVSYYIIEVRKAIKAKQLLAEGVNPTT 129


>UniRef50_A5GSN0 Large-conductance mechanosensitive channel n=1 Tax=Synechococcus
          sp. RCC307 RepID=A5GSN0_SYNR3
          Length = 128

 Score = 55.7 bits (133), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 23/57 (40%), Positives = 32/57 (56%)

Query: 2  SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFA 58
           + +EF +F  RGNVVDLAV VIIGAAF K+V ++V       L   +  +     +
Sbjct: 8  GLGREFLDFINRGNVVDLAVAVIIGAAFTKVVQAVVELFTTAALNPTMAELGIDSIS 64


>UniRef50_A7HMH6 Putative uncharacterized protein n=1 Tax=Fervidobacterium nodosum
          Rt17-B1 RepID=A7HMH6_FERNB
          Length = 61

 Score = 53.0 bits (126), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 18/44 (40%), Positives = 28/44 (63%)

Query: 2  SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPL 45
            +KEF +F  + NV+ LAV +IIG    + V+S V D++MP +
Sbjct: 3  KFMKEFSDFLKQYNVIGLAVAIIIGGKLNQFVTSFVNDLLMPAI 46


>UniRef50_UPI0000D52968 hypothetical protein P700755_20866 n=1 Tax=Psychroflexus torquis
           ATCC 700755 RepID=UPI0000D52968
          Length = 81

 Score = 52.6 bits (125), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 75  YGVFIQNVFDFLIVAFAIFMAIKLINKLNRK---KEEPAAAPAPTKEEVLLTEIRD 127
           +G F+  + ++LI+AF +F+ IK  N        ++        +KE  LL EIRD
Sbjct: 18  FGAFLGEIINYLIIAFVMFLVIKAYNHFEDMVDDEDNEEIVATESKEVTLLKEIRD 73


>UniRef50_Q03WP0 Large-conductance mechanosensitive channel n=2 Tax=Leuconostoc
           mesenteroides RepID=Q03WP0_LEUMM
          Length = 158

 Score = 45.7 bits (107), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 27/133 (20%), Positives = 50/133 (37%), Gaps = 13/133 (9%)

Query: 5   KEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDA 64
            EFR+F     ++ L++GVI+G +          D+I   +        +    +  ++ 
Sbjct: 18  NEFRKFITSPAIIQLSIGVIVGGSLT--------DLIKSVISFASNLFYYLSLLLFSKNH 69

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEP-----AAAPAPTKEE 119
              I  V+       +N      +A  +F  +KL+NK   K+        A      K  
Sbjct: 70  SAKINLVLDPLRSVFENFLTLCTIAACVFFFVKLVNKFLIKEASETLGYNAQLEETKKLI 129

Query: 120 VLLTEIRDLLKEQ 132
            +  E  +LLK+ 
Sbjct: 130 KIQHETNELLKKS 142


>UniRef50_A7HMH7 Putative uncharacterized protein n=1 Tax=Fervidobacterium nodosum
           Rt17-B1 RepID=A7HMH7_FERNB
          Length = 66

 Score = 43.0 bits (100), Expect = 0.003,   Method: Composition-based stats.
 Identities = 18/54 (33%), Positives = 26/54 (48%)

Query: 65  QGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE 118
              I    +++G  +    DFLIVAF +F+ IK +NK   K +  A   A   E
Sbjct: 4   IEQINWHGIYWGKVVSAGIDFLIVAFLVFLLIKSMNKAAEKTKVAAELAAKKVE 57


>UniRef50_C4Z968 Putative uncharacterized protein n=1 Tax=Eubacterium rectale ATCC
           33656 RepID=C4Z968_EUBR3
          Length = 76

 Score = 42.2 bits (98), Expect = 0.005,   Method: Composition-based stats.
 Identities = 12/42 (28%), Positives = 19/42 (45%)

Query: 77  VFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKE 118
            F+  V +FLI+A  +F  +K +N    +          TKE
Sbjct: 24  KFLTAVVNFLIMALIVFCIVKAMNAAGERFGHKEEKEPDTKE 65


>UniRef50_A2C9D0 Possible large-conductance mechanosensitive channel mscL n=2
           Tax=Prochlorococcus marinus RepID=A2C9D0_PROM3
          Length = 130

 Score = 39.1 bits (90), Expect = 0.041,   Method: Composition-based stats.
 Identities = 27/103 (26%), Positives = 55/103 (53%), Gaps = 13/103 (12%)

Query: 2   SIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTL 61
           +++ +F +F  RGNVVDLAV V++G AF K+V +LV  +    +  ++  +  +  +   
Sbjct: 9   NVLNDFTDFVNRGNVVDLAVAVVVGGAFSKVVDALVKLVTTAVMDPVLRKLKVETLS--- 65

Query: 62  RDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNR 104
                      +  G  + ++ +FL++AF +F+ ++ I +  R
Sbjct: 66  ----------AVPGGGLLVSMINFLVIAFVVFIVVRAIERFKR 98


>UniRef50_Q8PSE0 Large-conductance mechanosensitive channel n=1 Tax=Methanosarcina
          mazei RepID=Q8PSE0_METMA
          Length = 77

 Score = 38.0 bits (87), Expect = 0.086,   Method: Composition-based stats.
 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 7/60 (11%)

Query: 25 IGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFD 84
          +G A    + S V +IIMP +   I G          R A  DI  +V+ +G F+  + +
Sbjct: 1  MGIASTAFIKSFVDNIIMPIITPFIPGG-------AWRTATLDIGPIVLGWGAFLGELIN 53


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.316    0.146    0.378 

Lambda     K      H
   0.267   0.0447    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 850,906,027
Number of Sequences: 3077464
Number of extensions: 33448042
Number of successful extensions: 259216
Number of sequences better than 1.0e-01: 189
Number of HSP's better than  0.1 without gapping: 513
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 257754
Number of HSP's gapped (non-prelim): 603
length of query: 136
length of database: 1,040,396,356
effective HSP length: 101
effective length of query: 35
effective length of database: 729,572,492
effective search space: 25535037220
effective search space used: 25535037220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.0 bits)
S2: 87 (38.0 bits)
