Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	T	N	T	H	T	L	Q	I	E	E	I	L	E	L	L	P	H	R	F	P	F	L	L	V	D	R	V	L	D	F	E	E	G	R	F	L	R	A	V	K	N	V	S	V	N	E	P	F	F	Q	G	H	F	P	G	K	P	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	P	G	V	L	I	L	E	A	M	A	Q	A	T	G	I	L	A	F	K	S	V	G	K	L	E	P	G	E	L	Y	Y	F	A	G	I	D	E	A	R	F	K	R	P	V	V	P	G	D	Q	M	I	M	E	V	T	F	E	K	T
Secondary structure
SS confidence
Disorder																							?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.
Sequence		R	R	G	L	T	R	F	K	G	V	A	L	V	D	G	K	V	V	C	E	A	T	M	M	C	A	R	S	R	E	A
Secondary structure
SS confidence
Disorder																													?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2glv chain A Region: 5 - 150 Aligned: 146 Modelled: 146 Confidence: 100.0% Identity: 42% PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-acyl carrier protein PDBTitle: crystal structure of (3r)-hydroxyacyl-acyl carrier protein2 dehydratase(fabz) mutant(y100a) from helicobacter pylori Phyre2 PDB 1z6b chain A domain 1 Region: 5 - 148 Aligned: 139 Modelled: 144 Confidence: 100.0% Identity: 47% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: FabZ-like Phyre2 PDB 3d6x chain A Region: 7 - 146 Aligned: 135 Modelled: 138 Confidence: 100.0% Identity: 45% PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; PDBTitle: crystal structure of campylobacter jejuni fabz Phyre2 PDB 1u1z chain A Region: 9 - 149 Aligned: 139 Modelled: 141 Confidence: 100.0% Identity: 55% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: FabZ-like Phyre2 PDB 1mka chain A Region: 2 - 151 Aligned: 146 Modelled: 150 Confidence: 100.0% Identity: 26% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: beta-Hydroxydecanol thiol ester dehydrase Phyre2 PDB 2cf2 chain L Region: 17 - 150 Aligned: 129 Modelled: 130 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: L: PDB Molecule:fatty acid synthase, dh domain; PDBTitle: architecture of mammalian fatty acid synthase Phyre2 PDB 3esi chain D Region: 22 - 146 Aligned: 115 Modelled: 125 Confidence: 99.8% Identity: 20% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from2 erwinia carotovora subsp. atroseptica. northeast3 structural genomics target ewr179 Phyre2 PDB 2qwz chain B Region: 1 - 149 Aligned: 138 Modelled: 149 Confidence: 98.4% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution Phyre2 PDB 3ir3 chain B Region: 31 - 151 Aligned: 109 Modelled: 118 Confidence: 98.4% Identity: 18% PDB header:lyase Chain: B: PDB Molecule:3-hydroxyacyl-thioester dehydratase 2; PDBTitle: crystal structure of human 3-hydroxyacyl-thioester dehydratase 22 (htd2) Phyre2 PDB 1wlu chain A domain 1 Region: 28 - 147 Aligned: 105 Modelled: 120 Confidence: 98.3% Identity: 16% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 1ixl chain A Region: 28 - 150 Aligned: 108 Modelled: 123 Confidence: 98.2% Identity: 18% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2f3x chain A Region: 28 - 149 Aligned: 108 Modelled: 122 Confidence: 98.2% Identity: 15% PDB header:gene regulation Chain: A: PDB Molecule:transcription factor fapr; PDBTitle: crystal structure of fapr (in complex with effector)- a2 global regulator of fatty acid biosynthesis in b. subtilis Phyre2 PDB 2b3n chain A domain 1 Region: 44 - 147 Aligned: 93 Modelled: 104 Confidence: 98.1% Identity: 22% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: MaoC-like Phyre2 PDB 1zki chain A domain 1 Region: 28 - 147 Aligned: 108 Modelled: 120 Confidence: 98.1% Identity: 11% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 1q6w chain A Region: 57 - 149 Aligned: 90 Modelled: 93 Confidence: 98.0% Identity: 23% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: MaoC-like Phyre2 PDB 3lwg chain B Region: 28 - 151 Aligned: 108 Modelled: 123 Confidence: 98.0% Identity: 12% PDB header:unknown function Chain: B: PDB Molecule:hp0420 homologue; PDBTitle: crystal structure of hp0420-homologue c46a from helicobacter2 felis Phyre2 PDB 1sc0 chain A Region: 5 - 147 Aligned: 131 Modelled: 135 Confidence: 97.9% Identity: 14% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2pim chain A Region: 28 - 146 Aligned: 107 Modelled: 112 Confidence: 97.9% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase, phenylacetic acid2 degradation-related protein (reut_b4779) from ralstonia eutropha3 jmp134 at 2.20 a resolution Phyre2 PDB 3qoo chain A Region: 32 - 142 Aligned: 107 Modelled: 111 Confidence: 97.8% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of hot-dog-like taci_0573 protein from2 thermanaerovibrio acidaminovorans Phyre2 PDB 2f41 chain A domain 1 Region: 25 - 146 Aligned: 104 Modelled: 122 Confidence: 97.8% Identity: 16% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 1 c2glvA_ 2 d1z6ba1 3 c3d6xA_ 4 d1u1za_ 5 d1mkaa_ 6 c2cf2L_ 7 c3esiD_ 8 c2qwzB_ 9 c3ir3B_ 10 d1wlua1 11 d1ixla_ 12 c2f3xA_ 13 d2b3na1 14 d1zkia1 15 d1q6wa_ 16 c3lwgB_ 17 d1sc0a_ 18 c2pimA_ 19 c3qooA_ 20 d2f41a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2glvA_ 100.0 42 PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-acyl carrier protein PDBTitle: crystal structure of (3r)-hydroxyacyl-acyl carrier protein2 dehydratase(fabz) mutant(y100a) from helicobacter pylori 2 d1z6ba1 100.0 47 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:FabZ-like 3 c3d6xA_ 100.0 45 PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; PDBTitle: crystal structure of campylobacter jejuni fabz 4 d1u1za_ 100.0 55 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:FabZ-like 5 d1mkaa_ 100.0 26 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:beta-Hydroxydecanol thiol ester dehydrase 6 c2cf2L_ 100.0 27 PDB header:transferase Chain: L: PDB Molecule:fatty acid synthase, dh domain; PDBTitle: architecture of mammalian fatty acid synthase 7 c3esiD_ 99.8 20 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from2 erwinia carotovora subsp. atroseptica. northeast3 structural genomics target ewr179 8 c2qwzB_ 98.4 14 PDB header:hydrolase Chain: B: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution 9 c3ir3B_ 98.4 18 PDB header:lyase Chain: B: PDB Molecule:3-hydroxyacyl-thioester dehydratase 2; PDBTitle: crystal structure of human 3-hydroxyacyl-thioester dehydratase 22 (htd2) 10 d1wlua1 98.3 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 11 d1ixla_ 98.2 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 12 c2f3xA_ 98.2 15 PDB header:gene regulation Chain: A: PDB Molecule:transcription factor fapr; PDBTitle: crystal structure of fapr (in complex with effector)- a2 global regulator of fatty acid biosynthesis in b. subtilis 13 d2b3na1 98.1 22 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 14 d1zkia1 98.1 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 15 d1q6wa_ 98.0 23 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 16 c3lwgB_ 98.0 12 PDB header:unknown function Chain: B: PDB Molecule:hp0420 homologue; PDBTitle: crystal structure of hp0420-homologue c46a from helicobacter2 felis 17 d1sc0a_ 97.9 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 18 c2pimA_ 97.9 21 PDB header:hydrolase Chain: A: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase, phenylacetic acid2 degradation-related protein (reut_b4779) from ralstonia eutropha3 jmp134 at 2.20 a resolution 19 c3qooA_ 97.8 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of hot-dog-like taci_0573 protein from2 thermanaerovibrio acidaminovorans 20 d2f41a1 97.8 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 21 d2f0xa1 not modelled 97.8 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 22 c3f1tB_ not modelled 97.8 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein q9i3c8_pseae; PDBTitle: crystal structure of the q9i3c8_pseae protein from pseudomonas2 aeruginosa. northeast structural genomics consortium target par319a. 23 d1iq6a_ not modelled 97.7 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 24 d2h4ua1 not modelled 97.7 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 25 c3kg9A_ not modelled 97.7 13 PDB header:lyase Chain: A: PDB Molecule:curk; PDBTitle: dehydratase domain from curk module of curacin polyketide synthase 26 c3bnvD_ not modelled 97.6 13 PDB header:unknown function Chain: D: PDB Molecule:cj0977; PDBTitle: crystal structure of cj0977, a sigma28-regulated virulence protein2 from campylobacter jejuni. 27 c2gvhC_ not modelled 97.6 18 PDB header:hydrolase Chain: C: PDB Molecule:agr_l_2016p; PDBTitle: crystal structure of acyl-coa hydrolase (15159470) from agrobacterium2 tumefaciens at 2.65 a resolution 28 c3exzA_ not modelled 97.6 19 PDB header:lyase Chain: A: PDB Molecule:maoc-like dehydratase; PDBTitle: crystal structure of the maoc-like dehydratase from rhodospirillum2 rubrum. northeast structural genomics consortium target rrr103a. 29 c3kg6C_ not modelled 97.6 15 PDB header:lyase Chain: C: PDB Molecule:curf; PDBTitle: dehydratase domain from curf module of curacin polyketide synthase 30 c3el6A_ not modelled 97.6 17 PDB header:lyase Chain: A: PDB Molecule:erythromycin dehydratase; PDBTitle: crystal structure of the erythromycin dehydratase 31 d1vh9a_ not modelled 97.6 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 32 c3hduB_ not modelled 97.5 14 PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (syn_01977) from2 syntrophus aciditrophicus sb at 2.50 a resolution 33 d2gvha2 not modelled 97.5 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 34 d1y7ua1 not modelled 97.5 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 35 c2v1oF_ not modelled 97.4 16 PDB header:hydrolase Chain: F: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of n-terminal domain of acyl-coa2 thioesterase 7 36 d1ylia1 not modelled 97.4 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 37 c2bi0A_ not modelled 97.4 14 PDB header:hypothetical protein Chain: A: PDB Molecule:hypothetical protein rv0216; PDBTitle: rv0216, a conserved hypothetical protein from mycobacterium2 tuberculosis that is essential for bacterial survival3 during infection, has a double hotdogfold 38 c3kh8B_ not modelled 97.3 16 PDB header:lyase Chain: B: PDB Molecule:maoc-like dehydratase; PDBTitle: crystal structure of maoc-like dehydratase from phytophthora capsici 39 d2oiwa1 not modelled 97.3 7 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 40 c3e29C_ not modelled 97.3 14 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein q7we92_borbr; PDBTitle: x-ray structure of the protein q7we92_borbr from thioesterase2 superfamily. northeast structural genomics consortium target bor214a. 41 d1vpma_ not modelled 97.3 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 42 c2eisA_ not modelled 97.3 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tthb207; PDBTitle: x-ray structure of acyl-coa hydrolase-like protein, tt1379, from2 thermus thermophilus hb8 43 d2c2ia1 not modelled 97.2 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 44 d2bi0a1 not modelled 97.2 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 45 c3e8pA_ not modelled 97.1 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the protein q8e9m7 from shewanella2 oneidensis related to thioesterase superfamily. northeast3 structural genomics consortium target sor246. 46 c3hm0C_ not modelled 97.1 12 PDB header:hydrolase Chain: C: PDB Molecule:probable thioesterase; PDBTitle: crystal structure of probable thioesterase from bartonella2 henselae 47 c3lbeA_ not modelled 97.1 13 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein smu.793; PDBTitle: the crystal structure of smu.793 from streptococcus mutans ua159 bound2 to acetyl coa 48 c3kuvB_ not modelled 97.1 11 PDB header:hydrolase Chain: B: PDB Molecule:fluoroacetyl coenzyme a thioesterase; PDBTitle: structural basis of the activity and substrate specificity of the2 fluoroacetyl-coa thioesterase flk - t42s mutant in complex with3 acetate. 49 d2cy9a1 not modelled 97.1 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 50 c3kg8A_ not modelled 97.1 14 PDB header:lyase Chain: A: PDB Molecule:curj; PDBTitle: dehydratase domain from curj module of curacin polyketide synthase 51 d1vh5a_ not modelled 97.1 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 52 d2fs2a1 not modelled 97.0 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 53 c3d6lA_ not modelled 97.0 20 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of cj0915, a hexameric hotdog fold2 thioesterase of campylobacter jejuni 54 c3rd7A_ not modelled 97.0 20 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase; PDBTitle: crystal structure of acyl-coa thioesterase from mycobacterium avium 55 d2gvha1 not modelled 96.9 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 56 c3nwzD_ not modelled 96.9 10 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:bh2602 protein; PDBTitle: crystal structure of bh2602 protein from bacillus halodurans with coa,2 northeast structural genomics consortium target bhr199 57 c3b7kA_ not modelled 96.9 15 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 12; PDBTitle: human acyl-coenzyme a thioesterase 12 58 c3gekA_ not modelled 96.9 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thioesterase yhda; PDBTitle: crystal structure of putative thioesterase yhda from lactococcus2 lactis. northeast structural genomics consortium target kr113 59 d1pn2a2 not modelled 96.9 22 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 60 d2fuja1 not modelled 96.9 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 61 d1s9ca1 not modelled 96.8 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 62 d1q4ua_ not modelled 96.8 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 63 d2gf6a1 not modelled 96.8 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 64 d1c8ua1 not modelled 96.7 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 65 c3hrqB_ not modelled 96.7 14 PDB header:biosynthetic protein Chain: B: PDB Molecule:aflatoxin biosynthesis polyketide synthase; PDBTitle: the product template domain from pksa with palmitate bound 66 c3s4kA_ not modelled 96.7 12 PDB header:hydrolase Chain: A: PDB Molecule:putative esterase rv1847/mt1895; PDBTitle: structure of a putative esterase rv1847/mt1895 from mycobacterium2 tuberculosis 67 d2cyea1 not modelled 96.7 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 68 d2cwza1 not modelled 96.7 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:TTHA0967-like 69 d2hboa1 not modelled 96.7 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 70 c2qq2C_ not modelled 96.7 13 PDB header:hydrolase Chain: C: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of c-terminal domain of human acyl-coa thioesterase2 7 71 c1pn2D_ not modelled 96.6 22 PDB header:lyase Chain: D: PDB Molecule:peroxisomal hydratase-dehydrogenase-epimerase; PDBTitle: crystal structure analysis of the selenomethionine labelled2 2-enoyl-coa hydratase 2 domain of candida tropicalis3 multifunctional enzyme type 2 72 c1c8uA_ not modelled 96.6 15 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase ii; PDBTitle: crystal structure of the e.coli thioesterase ii, a2 homologue of the human nef-binding enzyme 73 c3khpB_ not modelled 96.5 25 PDB header:oxidoreductase Chain: B: PDB Molecule:maoc family protein; PDBTitle: crystal structure of a possible dehydrogenase from2 mycobacterium tuberculosis at 2.3a resolution 74 c3bbjA_ not modelled 96.5 16 PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase ii; PDBTitle: crystal structure of a putative thioesterase ii (tfu_2367) from2 thermobifida fusca yx at 2.45 a resolution 75 c1s9cK_ not modelled 96.5 20 PDB header:lyase Chain: K: PDB Molecule:peroxisomal multifunctional enzyme type 2; PDBTitle: crystal structure analysis of the 2-enoyl-coa hydratase 22 domain of human peroxisomal multifunctional enzyme type 2 76 d2hx5a1 not modelled 96.5 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 77 d2q78a1 not modelled 96.4 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:TTHA0967-like 78 c2egiE_ not modelled 96.4 16 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:hypothetical protein aq_1494; PDBTitle: crystal structure of a hypothetical protein(aq1494) from aquifex2 aeolicus 79 c3rqbB_ not modelled 96.4 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of conserved protein of unknown function with hot2 dog fold from alicyclobacillus acidocaldarius 80 c2cdhT_ not modelled 96.3 21 PDB header:transferase Chain: T: PDB Molecule:dehydratase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. 81 d2hlja1 not modelled 96.1 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 82 c3kg7C_ not modelled 96.1 15 PDB header:lyase Chain: C: PDB Molecule:curh; PDBTitle: dehydratase domain from curh module of curacin polyketide synthase 83 d2oafa1 not modelled 96.1 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 84 c2aliA_ not modelled 96.0 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pa2801; PDBTitle: structure of protein of unknown function pa2801 from pseudomonas2 aeruginosa, putative thioesterase 85 d2alia1 not modelled 96.0 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 86 c3cjyA_ not modelled 96.0 17 PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of putative thioesterase (yp_496845.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.70 a resolution 87 d2ov9a1 not modelled 95.8 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 88 c2uvaI_ not modelled 95.7 15 PDB header:transferase Chain: I: PDB Molecule:fatty acid synthase beta subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the beta subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 89 d1tbua1 not modelled 95.7 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 90 d1njka_ not modelled 95.5 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 91 d1z54a1 not modelled 95.4 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 92 d2bi0a2 not modelled 95.3 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 93 d2o5ua1 not modelled 95.2 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 94 c3e1eE_ not modelled 95.2 16 PDB header:hydrolase Chain: E: PDB Molecule:thioesterase family protein; PDBTitle: crystal structure of a thioesterase family protein from2 silicibacter pomeroyi. northeast structural genomics3 target sir180a 95 c3omlA_ not modelled 95.0 20 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:peroxisomal multifunctional enzyme type 2, cg3415; PDBTitle: structure of full-length peroxisomal multifunctional enzyme type 22 from drosophila melanogaster 96 c2pzhC_ not modelled 94.8 13 PDB header:hydrolase Chain: C: PDB Molecule:hypothetical protein hp_0496; PDBTitle: ybgc thioesterase (hp0496) from helicobacter pylori 97 c2xflB_ not modelled 94.7 9 PDB header:hydrolase Chain: B: PDB Molecule:dyne7; PDBTitle: induced-fit and allosteric effects upon polyene binding2 revealed by crystal structures of the dynemicin3 thioesterase 98 d1t82a_ not modelled 94.6 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 99 d1sh8a_ not modelled 94.2 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 100 d2nuja1 not modelled 94.1 8 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 101 c2vkzH_ not modelled 94.1 13 PDB header:transferase Chain: H: PDB Molecule:fatty acid synthase subunit beta; PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex 102 d2owna2 not modelled 94.0 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 103 c2w3xE_ not modelled 93.8 13 PDB header:hydrolase Chain: E: PDB Molecule:cale7; PDBTitle: crystal structure of a bifunctional hotdog fold2 thioesterase in enediyne biosynthesis, cale7 104 c3dkzA_ not modelled 93.8 12 PDB header:hydrolase Chain: A: PDB Molecule:thioesterase superfamily protein; PDBTitle: crystal structure of the q7w9w5_borpa protein from2 bordetella parapertussis. northeast structural genomics3 consortium target bpr208c. 105 d1s5ua_ not modelled 93.7 8 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 106 d2owna1 not modelled 93.4 6 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 107 c3ck1B_ not modelled 93.2 14 PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (reut_a2179) from2 ralstonia eutropha jmp134 at 1.74 a resolution 108 c2essA_ not modelled 92.2 13 PDB header:hydrolase Chain: A: PDB Molecule:acyl-acp thioesterase; PDBTitle: crystal structure of an acyl-acp thioesterase (np_810988.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.90 a resolution 109 d2essa1 not modelled 91.9 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 110 c2prxB_ not modelled 91.1 10 PDB header:hydrolase Chain: B: PDB Molecule:thioesterase superfamily protein; PDBTitle: crystal structure of thioesterase superfamily protein (zp_00837258.1)2 from shewanella loihica pv-4 at 1.65 a resolution 111 c2ownA_ not modelled 88.9 6 PDB header:hydrolase Chain: A: PDB Molecule:putative oleoyl-[acyl-carrier protein] thioesterase; PDBTitle: crystal structure of oleoyl thioesterase (putative) (np_784467.1) from2 lactobacillus plantarum at 2.00 a resolution 112 d1lo7a_ not modelled 88.1 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 113 c3lmbA_ not modelled 85.1 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein olei01261 with unknown function2 from chlorobaculum tepidum tls 114 d2essa2 not modelled 80.5 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 115 d1yoca1 not modelled 79.4 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 116 d1s9ca2 not modelled 78.3 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 117 d1c8ua2 not modelled 65.9 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0