BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (848 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_D2TCR5 CyaA protein n=3 Tax=Erwinia RepID=D2TCR5_ERWPY      1472   0.0  
UniRef50_Q59685 Adenylate cyclase n=330 Tax=cellular organisms R...  1360   0.0  
UniRef50_C4LDV3 Adenylate cyclase n=2 Tax=Gammaproteobacteria Re...   848   0.0  
UniRef50_A1SR20 Adenylate cyclase n=3 Tax=Psychromonas RepID=A1S...   769   0.0  
UniRef50_P40134 Adenylate cyclase n=25 Tax=Pasteurellaceae RepID...   653   0.0  
UniRef50_B3H1T6 Adenylate cyclase n=12 Tax=Pasteurellaceae RepID...   648   0.0  
UniRef50_C0ARX7 Putative uncharacterized protein n=1 Tax=Proteus...   533   e-150
UniRef50_Q1I310 Adenylate cyclase n=23 Tax=Pseudomonas RepID=Q1I...   453   e-125
UniRef50_A0Y9E5 Adenylate cyclase, class I n=1 Tax=marine gamma ...   428   e-118
UniRef50_Q2SQ66 Adenylate cyclase n=1 Tax=Hahella chejuensis KCT...   410   e-112
UniRef50_A1SAP9 Adenylate cyclase n=18 Tax=Shewanella RepID=A1SA...   405   e-111
UniRef50_Q1N416 Adenylate cyclase n=1 Tax=Bermanella marisrubri ...   382   e-104
UniRef50_A4BK19 Adenylate cyclase, class I n=1 Tax=Reinekea blan...   382   e-104
UniRef50_A1TXX4 Adenylate cyclase n=2 Tax=Marinobacter RepID=A1T...   382   e-104
UniRef50_UPI00019102CE adenylate cyclase n=2 Tax=Salmonella ente...   380   e-103
UniRef50_Q21EM4 Adenylate cyclase n=1 Tax=Saccharophagus degrada...   377   e-102
UniRef50_C0ARX6 Putative uncharacterized protein n=1 Tax=Proteus...   372   e-101
UniRef50_C5BLM3 Adenylate cyclase, class I n=1 Tax=Teredinibacte...   355   6e-96
UniRef50_B3PH57 Adenylate cyclase, class I n=1 Tax=Cellvibrio ja...   351   6e-95
UniRef50_Q088L2 Adenylate cyclase n=1 Tax=Shewanella frigidimari...   347   1e-93
UniRef50_D1U0N4 Conserved domain protein n=1 Tax=Yersinia pestis...   282   5e-74
UniRef50_C4TXU8 Putative uncharacterized protein n=4 Tax=Enterob...   240   2e-61
UniRef50_C8R2N0 Putative adenylate cyclase n=1 Tax=Desulfurivibr...   211   7e-53
UniRef50_Q1NP63 Adenylate cyclase n=2 Tax=delta proteobacterium ...   195   8e-48
UniRef50_C0QEU2 CyaA2 n=1 Tax=Desulfobacterium autotrophicum HRM...   194   1e-47
UniRef50_B4RT26 Adenylate cyclase, class I n=2 Tax=Alteromonas m...   192   7e-47
UniRef50_Q2LSY1 Adenylate cyclase n=1 Tax=Syntrophus aciditrophi...   154   2e-35
UniRef50_D1U9E3 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   149   4e-34
UniRef50_C6BYH9 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   148   1e-33
UniRef50_C4XU05 Putative uncharacterized protein n=1 Tax=Desulfo...   130   3e-28
UniRef50_C0N363 Putative uncharacterized protein n=1 Tax=Methylo...   127   3e-27
UniRef50_D2L1I3 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   126   4e-27
UniRef50_A4P0R1 Adenylate cyclase n=2 Tax=Haemophilus influenzae...    52   7e-05

>UniRef50_D2TCR5 CyaA protein n=3 Tax=Erwinia RepID=D2TCR5_ERWPY
          Length = 887

 Score = 1472 bits (3812), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 698/831 (83%), Positives = 768/831 (92%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           +YLYIETLKQRLDAINQLRVDRALAAMG AFQQVYSLLPTLLHYHHPLMPGYL+GNVP G
Sbjct: 37  LYLYIETLKQRLDAINQLRVDRALAAMGSAFQQVYSLLPTLLHYHHPLMPGYLEGNVPHG 96

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           I  YTPDE+Q  YL+ LE   G     PP GE+P+TGVY+MGSTSSVGQ+ +SDLDIWVC
Sbjct: 97  ISFYTPDESQLSYLHGLEGQSGSDAAVPPHGEMPVTGVYSMGSTSSVGQNGTSDLDIWVC 156

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           HQSWLD++ER  LQ+KC LL+NW   +GVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI
Sbjct: 157 HQSWLDNDERLSLQKKCILLQNWCVEMGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 216

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLLDEFYRTAVR+AGKRILWNMVP +EEE YDDYVM+LY +GVLTPNEWLDLGGL +LSA
Sbjct: 217 LLLDEFYRTAVRMAGKRILWNMVPREEEEQYDDYVMSLYQRGVLTPNEWLDLGGLGTLSA 276

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
           EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP+ RLLA DIKQRLHDGEIVS+GLD
Sbjct: 277 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPDTRLLAMDIKQRLHDGEIVSYGLD 336

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGW 360
           PYCMMLERVT YL  I+D  RLDLVRRCFYLKVCEKLS      GWRR +LSQLV EWGW
Sbjct: 337 PYCMMLERVTRYLIGIDDPARLDLVRRCFYLKVCEKLSLAAENSGWRREILSQLVQEWGW 396

Query: 361 DEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR 420
           D+ RLAMLD+RA WKI QVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR
Sbjct: 397 DKQRLAMLDSRAGWKIGQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR 456

Query: 421 KLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQ 480
           KLYAAFEALPGKVTL+NPQISPDLSE +LTFI+VP GRANR+GWYLYN++P+++SIISHQ
Sbjct: 457 KLYAAFEALPGKVTLLNPQISPDLSESDLTFIHVPNGRANRAGWYLYNQSPDMDSIISHQ 516

Query: 481 PLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTP 540
           PLEYNRYLNKLVAWAWFNGLLTS+TRL+IKGN   DL +LQE+VADV+HHFP+RL APT 
Sbjct: 517 PLEYNRYLNKLVAWAWFNGLLTSKTRLHIKGNESCDLARLQELVADVTHHFPVRLAAPTA 576

Query: 541 KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRN 600
           KALYSPCEIRHLAII+NLE DPTAAFRNQVVHFDFRKLDVFSFG+ Q CLVGSVDLLYRN
Sbjct: 577 KALYSPCEIRHLAIIINLEVDPTAAFRNQVVHFDFRKLDVFSFGQQQQCLVGSVDLLYRN 636

Query: 601 SWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSE 660
           SWNEVRTLHFNGEQSMIEALKTILGKMHQDA+PPDSV+VFCYSQHLRGLIRTRVQQLVSE
Sbjct: 637 SWNEVRTLHFNGEQSMIEALKTILGKMHQDASPPDSVDVFCYSQHLRGLIRTRVQQLVSE 696

Query: 661 CIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSV 720
           C+ELRLSSTRQE GRFKALRV+GQTWGLFFERL+VSVQKLENA+EFYGAIS+NKLHGLS+
Sbjct: 697 CVELRLSSTRQEPGRFKALRVAGQTWGLFFERLSVSVQKLENAVEFYGAISNNKLHGLSL 756

Query: 721 QVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELV 780
           +VE++  +LPAVV+G+ASEGIIQFFFE+T++++GFNIYILDE+NRVEVYHHCEGSKEELV
Sbjct: 757 KVESDQARLPAVVNGYASEGIIQFFFEDTRNDHGFNIYILDETNRVEVYHHCEGSKEELV 816

Query: 781 RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNM 831
           RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIV+V+ R +VIPFR++++  +
Sbjct: 817 RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVQVEERCEVIPFRSQAMTQL 867


>UniRef50_Q59685 Adenylate cyclase n=330 Tax=cellular organisms RepID=CYAA_PROMI
          Length = 865

 Score = 1360 bits (3519), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 649/839 (77%), Positives = 727/839 (86%), Gaps = 11/839 (1%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLR++RA A+M   F+QVY L+P LLHYHHP +PGY+ GNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRLERAFASMSDVFKQVYGLIPVLLHYHHPQLPGYIQGNVPHG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDP----PKGELPITGVYTMGSTSSVGQSCSSDLD 116
            C + PD+ QR ++N+L      S  +P      GELPITG+Y+MGSTSS+GQS  SD+D
Sbjct: 61  TCFFEPDDVQRQWVNKLT---NASCDEPMNGYTSGELPITGIYSMGSTSSIGQSHCSDID 117

Query: 117 IWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGS 176
           IWVCHQSWLD +ER  LQRKC L+E WA  LG++V+FFLIDENRFRH+ SGSLGGEDCGS
Sbjct: 118 IWVCHQSWLDQDERARLQRKCLLIEQWAGELGIDVTFFLIDENRFRHHASGSLGGEDCGS 177

Query: 177 TQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLS 236
           TQHILLLDEFYRTAVRLAGKR+LW MVP +EE HYD+YV +LYAQGVLTPNEWLDLGGL 
Sbjct: 178 TQHILLLDEFYRTAVRLAGKRLLWTMVPVEEEYHYDEYVNSLYAQGVLTPNEWLDLGGLG 237

Query: 237 SLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVS 296
            LSAEEYFGASLWQLYKS+DSPYKAVLK++LLEAYS +YPN +LLA ++KQ LH GEIV+
Sbjct: 238 ELSAEEYFGASLWQLYKSVDSPYKAVLKSILLEAYSADYPNGKLLALEMKQHLHRGEIVN 297

Query: 297 FGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRER---ACVGWRRAVLSQ 353
           +GLD YCMMLERVT YL +I D TRLDL+RRCFYLKVCEKLS E+      GWRR VLSQ
Sbjct: 298 YGLDAYCMMLERVTRYLVSINDLTRLDLIRRCFYLKVCEKLSNEKNENEPAGWRRQVLSQ 357

Query: 354 LVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQ 413
           LV++W WD  RLA+LDNR +WKI++VR AHNELLD MMQSYRNLIRFARRNNLSVSASPQ
Sbjct: 358 LVTQWQWDHERLAILDNRDSWKIERVRNAHNELLDTMMQSYRNLIRFARRNNLSVSASPQ 417

Query: 414 DIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNI 473
           DIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEP+LTFIYVPPGRANRSGWYLYNRAP+ 
Sbjct: 418 DIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPHLTFIYVPPGRANRSGWYLYNRAPDF 477

Query: 474 ESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFP 532
             I+ HQPLEYNRYLNKLVAW++FNGLLT  +++YI +G+   D  KL E+V D+S HFP
Sbjct: 478 AHIVGHQPLEYNRYLNKLVAWSYFNGLLTKDSQVYIHQGDSSCDEIKLHELVRDISSHFP 537

Query: 533 LRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVG 592
           +RLPAPTPKALYSPCEIRHLAIIVNLE DPT  F +QVVHFDFRKLDVFSFGE + CL+G
Sbjct: 538 IRLPAPTPKALYSPCEIRHLAIIVNLEVDPTERFSDQVVHFDFRKLDVFSFGEEEQCLIG 597

Query: 593 SVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRT 652
           S+DLLYRNSWNEVRTLHFNG QSM+E+LKTILGKMHQDAAPP SVEVFCYSQHLRGLIRT
Sbjct: 598 SIDLLYRNSWNEVRTLHFNGTQSMLESLKTILGKMHQDAAPPASVEVFCYSQHLRGLIRT 657

Query: 653 RVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISH 712
           RVQQLVSECIELRLS+ R E GRFKALR++GQTWGLFFERLNVSVQKLENAIEFYGAIS+
Sbjct: 658 RVQQLVSECIELRLSTNRLEPGRFKALRIAGQTWGLFFERLNVSVQKLENAIEFYGAISY 717

Query: 713 NKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHC 772
           NKLHGL V++  +   LPAV+DGFA EGIIQFFFE T+D N FNIYILDE+NRVE+Y HC
Sbjct: 718 NKLHGLPVKLGKDARYLPAVIDGFACEGIIQFFFETTEDNNVFNIYILDEANRVEIYSHC 777

Query: 773 EGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNM 831
           EGSKEELV+DVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDG  QV+PF   S G +
Sbjct: 778 EGSKEELVKDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGATQVLPFAGGSFGKL 836


>UniRef50_C4LDV3 Adenylate cyclase n=2 Tax=Gammaproteobacteria RepID=C4LDV3_TOLAT
          Length = 830

 Score =  848 bits (2191), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 420/836 (50%), Positives = 573/836 (68%), Gaps = 15/836 (1%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           M+   E L  R DAINQ++++RAL AM  A +++ S+LP LLHYHHP +PGY+ G VP G
Sbjct: 1   MFKQFELLVARCDAINQIKMERALEAMNEAGRRMLSMLPVLLHYHHPHLPGYVSGEVPCG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           I  + PD  QR +L      +     +P   E  ++ VYTMGSTSS+GQS  SDLDIW+C
Sbjct: 61  IANFQPDAAQRKFL----FTQCGHTAEPEVKECCLSAVYTMGSTSSIGQSTVSDLDIWIC 116

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           H   L +E R LL++KC  L   A    VE++FFLI EN+FR      +G ++CGS QH+
Sbjct: 117 HDPALSAERRALLEQKCQFLSRLAEQHSVEMNFFLIPENKFRVGNQAQVGLDNCGSAQHL 176

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLL+EFYR+A R+AGKR+LW ++P + E+ YD     L++ G+++ ++WLDLGG+  + A
Sbjct: 177 LLLEEFYRSATRVAGKRLLWPLIPVEREDEYDALAAALFSTGMISEDDWLDLGGVGHIPA 236

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
           EEYFG++LW LYK +DSPYKAVLK L++EAYS E+P+  LLA   K+     +     LD
Sbjct: 237 EEYFGSALWLLYKGLDSPYKAVLKILVMEAYSAEFPHTDLLAVQAKRWFQQHDEFGLSLD 296

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVG--WRRAVLSQLVSEW 358
            Y +ML++VT+YLT + D  RLDL RRCFYLK+C+ LSR        WRR +L +LV +W
Sbjct: 297 AYYLMLDKVTDYLTKLGDTKRLDLARRCFYLKICDPLSRNVPPQHGRWRRDLLVKLVRDW 356

Query: 359 GWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
           GWD A L  LD+   WK++QV+ A+ ELL ++MQSY  LI+FARRNN+S S +P+DIG+L
Sbjct: 357 GWDHATLQHLDSHDQWKVEQVKTAYEELLSSLMQSYSKLIQFARRNNISESINPEDIGIL 416

Query: 419 TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIIS 478
           +RKLY AFEALPGKV  +N +I+PDL E +L+ I VPPG  NR GWYLY  +     II 
Sbjct: 417 SRKLYTAFEALPGKVQRINLKIAPDLHESDLSLIQVPPGHLNRQGWYLYKYSLKPHDIIG 476

Query: 479 HQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPK--LQEMVADVSHHFPLRLP 536
             PLEYN YL+KLVAWA+FNGL+ + TR+ I+  G  D+ +  L +   D++  FP+ LP
Sbjct: 477 RAPLEYNGYLSKLVAWAYFNGLMVANTRIDIRQAG-SDITRTCLHQFCQDLADTFPVELP 535

Query: 537 APTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDL 596
             +  AL  PCEIRHL I +NLE DPTA +  ++        D+  FG  Q CL+G+VDL
Sbjct: 536 PASNLALSRPCEIRHLGIFLNLERDPTADWPEEMPPVLEHGEDMLCFGARQECLIGTVDL 595

Query: 597 LYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQ 656
           +YRNSWNEVRTLHFNG  +++EAL TIL KMHQDAA PD+++VFCYSQ+ R  IR +  +
Sbjct: 596 VYRNSWNEVRTLHFNGLDAVVEALSTILSKMHQDAAAPDAIDVFCYSQYYRDEIRHQFTE 655

Query: 657 LVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLH 716
           LV+ CI LRL+  +Q     K L V    + LF ER  VSV++L +AI+FY  +S NKL 
Sbjct: 656 LVNSCISLRLALDKQRM--VKLLSVGEHRYALFLERRGVSVRQLSSAIDFYRQVSDNKLE 713

Query: 717 GLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSK 776
             + + + N + +P +VD +ASEG+IQ+FFE+  ++NGFN+YILDE+N+VE+YH   GSK
Sbjct: 714 RQTAEPD-NGLHVPPIVDAYASEGLIQYFFED--NDNGFNVYILDENNKVEIYHEYAGSK 770

Query: 777 EELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMP 832
           E+LV++V+R+Y+ +H RF +    INFNLPQFY++V      QV P+R+ ++  MP
Sbjct: 771 EDLVQNVNRYYTMTHQRFDFTEQVINFNLPQFYELVPGSDSLQVTPYRS-AMREMP 825


>UniRef50_A1SR20 Adenylate cyclase n=3 Tax=Psychromonas RepID=A1SR20_PSYIN
          Length = 869

 Score =  769 bits (1985), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 387/864 (44%), Positives = 549/864 (63%), Gaps = 42/864 (4%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           I+ L+ + D + +LR+  A   M      V+   P LLHY+HP +PGY  G+ P GI  +
Sbjct: 13  IKRLRDKADELTRLRIQSAELLMNADTLTVFRTFPLLLHYNHPSLPGYTKGDTPTGIHQF 72

Query: 65  TPDETQRHYLNEL-------------------------ELYRGMSVQDPPKG---ELPIT 96
             ++ Q+  L EL                         +L   +S QD P+    +  + 
Sbjct: 73  NVNKKQKKQLAELFPYQEEPQKKAQATNLITKPTDLKIQLNNLLSFQDEPQKKPQQADLI 132

Query: 97  GVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLI 156
           G+Y MGST+S+GQS  SDLDIW+C+   +D +  QLL+ K  L+ +WA   GVE++FFLI
Sbjct: 133 GLYAMGSTASIGQSSESDLDIWICYPHQMDKQRVQLLKNKSWLITHWAEGYGVELNFFLI 192

Query: 157 DENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVM 216
            +N+FR +    +  + CG++QH+LLLDEFYRT + +AGKRILW  VP + E++Y++YV 
Sbjct: 193 PDNKFRIDNKSDMTMDACGTSQHLLLLDEFYRTELHIAGKRILWWQVPFEHEKNYNEYVK 252

Query: 217 TLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP 276
            LY  G L P++WLDLGG   + AEEYFGA+LWQLYK ID+PYKAVLKT+L+EAYSWEYP
Sbjct: 253 KLYDNGGLNPDDWLDLGGFDRIPAEEYFGATLWQLYKGIDTPYKAVLKTILMEAYSWEYP 312

Query: 277 NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEK 336
           N  L+A   K+R  + +     LDPYC+MLE+VT YL  I DF RL++VR CFYLK  E 
Sbjct: 313 NTELIALYYKKRFQEQQTDLEYLDPYCLMLEKVTSYLNKINDFKRLEVVRACFYLKTEEN 372

Query: 337 LSRERACV----GWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQ 392
           LS  + C      WRR VL++ V+ W W++  +A LDNR  WK+  V  A + LLD +M 
Sbjct: 373 LS--KICTLNPPTWRRQVLTKFVNRWDWNKDHIADLDNRKKWKVRAVSNAKDILLDTLMA 430

Query: 393 SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFI 452
           SY  L+RFAR NN+  S S +D+G+L+RKLYAA E+LPGKV L+NP+ISPDLSEP+L+FI
Sbjct: 431 SYSKLLRFARDNNIEGSISAEDLGILSRKLYAAHESLPGKVDLINPKISPDLSEPDLSFI 490

Query: 453 YVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTR--LYIK 510
            VP  R N +GWYLYN + +  ++I+   L Y +Y+ KLVAW   NGL    T+  LY +
Sbjct: 491 QVPKNRKNAAGWYLYNCSLDSFTLINTPTLMYAKYIAKLVAWCHMNGLYEEETQLHLYNQ 550

Query: 511 GNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQV 570
           G+ +VD  KL + + D+   FP+ +P  +  AL  PCEI+HL I +NLE DPT  + +  
Sbjct: 551 GSDLVD-KKLNQFIQDLYSVFPIYIPKASNNALSRPCEIKHLTIFLNLERDPTRHWESTS 609

Query: 571 VHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQD 630
              D ++ D+FS+GE++ CL+GS+DL+YRNSWNEVRTLHFN  QS+I+AL TILGKMHQ 
Sbjct: 610 ESEDDQQGDIFSYGEDKECLIGSIDLIYRNSWNEVRTLHFNSNQSVIDALHTILGKMHQG 669

Query: 631 AAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFF 690
           A PP+ +++FCYS   +  I    +  ++E I+LRL S  Q +   + L+   + +  +F
Sbjct: 670 ACPPEQIDLFCYSCQFQAQISQAFKSKLNEYIQLRLDSLSQRS--VQTLKTGEENFAFYF 727

Query: 691 ERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHV-KLPAVVDGFASEGIIQFFFEET 749
           E+  VSVQ L+N ++ Y  IS+ K+   ++ ++  +  K  +++    SEGI+QFFFE  
Sbjct: 728 EQTGVSVQHLKNLVDIYSHISNKKVSNSALNLKNTYFDKTVSIIGSHISEGIVQFFFENY 787

Query: 750 QDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFY 809
            D  GFN+YI +  N +E  H   G K++LV++V+RFY+S+++        INFNLPQFY
Sbjct: 788 HD--GFNVYIANADNEIETLHSFTGGKDDLVQNVNRFYASNNNEMNKQDDRINFNLPQFY 845

Query: 810 QIVKVDGREQVIPFRTKSIGNMPP 833
           +I   D +E ++   T +     P
Sbjct: 846 EIELSDNKELILSSFTSTTKENEP 869


>UniRef50_P40134 Adenylate cyclase n=25 Tax=Pasteurellaceae RepID=CYAA_HAEIN
          Length = 843

 Score =  653 bits (1685), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 357/843 (42%), Positives = 509/843 (60%), Gaps = 31/843 (3%)

Query: 9   KQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDE 68
           KQ + A++Q R +RAL   G AFQ V +++P LLH +HP +PGY+  + P GI  +   +
Sbjct: 9   KQWVSALDQRRFERALQGSGDAFQHVLAIVPLLLHLNHPQLPGYVI-HAPSGIASFLASD 67

Query: 69  TQRHYL-NELELYRGMSVQDPPKGEL-------PITGVYTMGSTSSVGQSCSSDLDIWVC 120
            Q+ +L NE  ++         K  +       PI GVY MGS  S+ Q+ SSDLD W+C
Sbjct: 68  YQKKWLTNEYGIHYADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSSSDLDTWIC 127

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNE-SGSLGGEDCGSTQH 179
            +  L  +E  LL +K   +  WA    VE++F+L+D+ RFR+   +  L  E+ GS Q+
Sbjct: 128 VRDGLSLDEYTLLTQKAKRISEWAMQFNVEINFYLMDQQRFRNEHYADPLTIENSGSAQY 187

Query: 180 ILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLS 239
           +LLLDEFYR+AVRLAGK +LW  +  + E+ Y+  V  L  +G + PN+W+D GGL   S
Sbjct: 188 MLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVDFGGLGQFS 247

Query: 240 AEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEI-VSFG 298
           A EYFGASLW LYK IDSPYK+VLK LLLEAYS EYPN  L+A+  K+ L  G       
Sbjct: 248 ANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLAGNTNPDHH 307

Query: 299 LDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEW 358
            DPY  +L +VT+YLTA+ +F RLD V RCFY+K  E  +R +A   WR   +  L  EW
Sbjct: 308 FDPYIAILAKVTQYLTALSEFKRLDFVHRCFYVKATEDFARYQAN-NWRIRYMEILAQEW 366

Query: 359 GWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
           GW    +  L+ R  WKI  V+E H+ ++  +M SYRNL+ FAR++++  S  PQDI +L
Sbjct: 367 GWSAETVKHLNKRPFWKIKAVKENHDNIMKFLMLSYRNLVEFARKHHIHSSVVPQDINIL 426

Query: 419 TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIIS 478
           +RKLY AFE LPGKV+L+N QIS +LSE +LTF+ V   +  + GWYL N+  +      
Sbjct: 427 SRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQPIHHIMFSK 486

Query: 479 HQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPA- 537
            + +EY   LNKLV+WA+FN LLT +T L I     V L  LQ  V ++   FP  +   
Sbjct: 487 ERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKN-VTLSTLQRFVTNLRQSFPSTIAKQ 545

Query: 538 PTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLL 597
           P    L + CEIR L I +NL  DPT+     +     R  D+FSFG  +  LVGS+D  
Sbjct: 546 PKNSDLLNQCEIRSLFIAINLTTDPTSKVEEVLTGISSR--DLFSFGSLEQSLVGSIDFT 603

Query: 598 YRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQL 657
           YRN WNE+RTLHF G+ +++ ALK +  K+++    PDS++V+CYS+  R  +R  V  L
Sbjct: 604 YRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRPDSIQVYCYSERYRQDLRQLVMGL 663

Query: 658 VSECIELRLSSTRQ--ETGRFKALRVSGQTWGLFFERLNVSVQKLENAI---EFYGAISH 712
           V+ C+ +++   +Q  +T R   LRV+G+ W LFFE   +S+Q++ N     E   A+  
Sbjct: 664 VNRCVSIQVGDIQQPCQTSR---LRVAGKNWQLFFEDRGISLQEIGNESVCNEAESAVDF 720

Query: 713 NKLHGLSVQ-VETNHV--KLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVY 769
           +++    ++  ETN    + P  +D FASEG +QFFFE+  D + FN+YILDESN +E+Y
Sbjct: 721 DEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSD-HSFNVYILDESNHLEIY 779

Query: 770 HHCEGSKEELVRDVSRFYSSSH---DRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTK 826
            HC+G K+E VR++++ Y ++    D+  Y     NFN PQFYQ+        ++PF+ +
Sbjct: 780 RHCDGEKDEKVREINQLYQNAKQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFR 839

Query: 827 SIG 829
            + 
Sbjct: 840 QMN 842


>UniRef50_B3H1T6 Adenylate cyclase n=12 Tax=Pasteurellaceae RepID=B3H1T6_ACTP7
          Length = 842

 Score =  648 bits (1671), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 339/818 (41%), Positives = 507/818 (61%), Gaps = 25/818 (3%)

Query: 11  RLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQ 70
           R+DA++  R  RALAA  P F+QV+SLLP L+H + P +P Y+  N P GI  +   E Q
Sbjct: 36  RVDALDHFRTQRALAANSPQFEQVFSLLPLLIHTNLPELPAYIK-NAPSGIAAFELSEYQ 94

Query: 71  RHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEER 130
            +YL+EL L   +++++     +   G+Y+MGST ++ Q+  SD+D+W+C+   L++ E 
Sbjct: 95  ANYLSELSL-SHLAIRNSA-DLVAFDGLYSMGSTGTITQTSLSDIDLWLCYSDRLNALEY 152

Query: 131 QLLQRKCSLLENWAASLGVEVSFFLIDENRFR-HNESGSLGGEDCGSTQHILLLDEFYRT 189
           QL+++K   ++ WA  LGV+VSF+L++   F+ H     +  E  GS QH  LLDEFYR+
Sbjct: 153 QLVEQKLDKIKQWAKRLGVDVSFYLMNPAHFKAHLYHSDVNEEHSGSAQHYFLLDEFYRS 212

Query: 190 AVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLW 249
           A+RLAGKR+LW  +P       D       +     P EW+D G  SSLS  E+FGASLW
Sbjct: 213 AIRLAGKRLLWLHLP-------DGLYQQYLSSAEFNPAEWIDFGDFSSLSTGEFFGASLW 265

Query: 250 QLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERV 309
           QLYK I+ PYK+ +K LLLE+Y+  YPN  L++K  KQ+L   + V +  DPY  MLE+V
Sbjct: 266 QLYKGIEYPYKSAIKILLLESYADTYPNTNLISKQFKQKLLAVQTVEYHFDPYLAMLEQV 325

Query: 310 TEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLD 369
           T+YL+  ++  RL  +R CFY+K  E  SRE     WR   L +L+  W W+   L +LD
Sbjct: 326 TDYLSKRKEMLRLSRLRMCFYVKASEGESRE----TWRTQALRELIEGWNWNLQELNLLD 381

Query: 370 NRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEAL 429
           NR NWKI Q       +++ ++QSYRNLI+FAR+ ++  S    DI +L RKLY+ FE  
Sbjct: 382 NRQNWKIKQAVTHQQIIVEQLLQSYRNLIQFARKFHIDPSILASDIDILMRKLYSVFEMA 441

Query: 430 PGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLN 489
           PGKV L+NPQIS +L+E  +TFI V  G A ++GWY+ N+AP      + + +   + L 
Sbjct: 442 PGKVPLINPQISENLAESAVTFIEVREGSAMQAGWYMINQAPRSPYDPALRYVRQAKNLT 501

Query: 490 KLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEI 549
           KLVAW +FNG++TS T+L++    + DL +L++ + D+   FP++ P      L  P EI
Sbjct: 502 KLVAWGYFNGVITSNTQLHLVSRSL-DLSRLRQFITDLRLSFPVKAPEMIDDDLLHPNEI 560

Query: 550 RHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLH 609
           R L + +NL  DPT     +      +  D+F+FG  Q  LVGSV ++YRN WNE+RT H
Sbjct: 561 RSLILAINLVKDPTQKL--EPTRRAVQPSDLFNFGSAQQSLVGSVSIIYRNLWNEIRTQH 618

Query: 610 FNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSST 669
           F G+ ++++ALK I  K+++ +A P SV VFCYS+HLR  +R  + +LV +CI ++  + 
Sbjct: 619 FEGDDAILKALKLISNKIYRSSASPQSVNVFCYSRHLRSELRDFIAELVHKCITIQTGTI 678

Query: 670 RQETGRFKALRVSGQTWGLFFERLNVSVQKL-ENAIEFYGAISHNKLHGLSVQVETNHVK 728
            Q+      L+V+G+ W   F +  V +Q L E A+EF   I+ N      +  ++N V 
Sbjct: 679 SQKQP-LSTLKVAGKMWQFVFGKQKVEIQPLNEQAVEFNQEIA-NLQDEAGMHAKSNCV- 735

Query: 729 LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYS 788
            P  +D FASEG +QFFFE+  DE  FN+YILDE N +EV H C  SKEE V++++R ++
Sbjct: 736 FPKEIDEFASEGFLQFFFEDNADE-SFNVYILDEKNTLEVCHDCFCSKEEKVKEINRIHA 794

Query: 789 SSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTK 826
           + + +    +S  +FN PQFYQ++ ++G+ +++PF++K
Sbjct: 795 AENSK--ENASLESFNFPQFYQLISLNGKTRIVPFQSK 830


>UniRef50_C0ARX7 Putative uncharacterized protein n=1 Tax=Proteus penneri ATCC 35198
           RepID=C0ARX7_9ENTR
          Length = 363

 Score =  533 bits (1374), Expect = e-150,   Method: Compositional matrix adjust.
 Identities = 251/346 (72%), Positives = 291/346 (84%), Gaps = 9/346 (2%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           +YLYIETLKQRLDAINQLR++RA A+M   F+QVY L+P LLHYHHP +PGY+ GNVP G
Sbjct: 19  LYLYIETLKQRLDAINQLRLERAFASMCDVFKQVYGLIPVLLHYHHPELPGYIQGNVPHG 78

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPP-----KGELPITGVYTMGSTSSVGQSCSSDL 115
            C + PD+ QR + N+L      ++ D P      GELPITG+Y+MGSTSS+GQS  SD+
Sbjct: 79  TCFFEPDDMQRQWANKLI----NALCDEPMEGYASGELPITGIYSMGSTSSIGQSHCSDI 134

Query: 116 DIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCG 175
           DIWVCHQSWLD +ER LLQRKC L+E WA  LG++V+FFLIDENRFRH+ SGSLGGEDCG
Sbjct: 135 DIWVCHQSWLDQDERALLQRKCQLIEQWAGELGIDVTFFLIDENRFRHHASGSLGGEDCG 194

Query: 176 STQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGL 235
           STQHILLLDEFYRTAVRLAGKR+LW MVP +EE HYD+YV +LYAQGVLTPNEWLDLGGL
Sbjct: 195 STQHILLLDEFYRTAVRLAGKRLLWTMVPVEEEHHYDEYVNSLYAQGVLTPNEWLDLGGL 254

Query: 236 SSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIV 295
             LSAEEYFGASLWQLYKS+DSPYKAVLK++LLEAYS +YPN +LLA ++KQ LH GEIV
Sbjct: 255 GELSAEEYFGASLWQLYKSVDSPYKAVLKSILLEAYSADYPNGKLLALEMKQHLHRGEIV 314

Query: 296 SFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRER 341
           ++GLD YCMMLERVT YL +I D TRLDL+RRCFYLKVCEKLS E+
Sbjct: 315 NYGLDAYCMMLERVTRYLVSINDLTRLDLIRRCFYLKVCEKLSNEK 360


>UniRef50_Q1I310 Adenylate cyclase n=23 Tax=Pseudomonas RepID=Q1I310_PSEE4
          Length = 954

 Score =  453 bits (1166), Expect = e-125,   Method: Compositional matrix adjust.
 Identities = 285/782 (36%), Positives = 420/782 (53%), Gaps = 45/782 (5%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           +  L+ R   INQ R+ RAL  +    QQV +LLP   H +HPL+PGY+ GN P G+  +
Sbjct: 20  LSRLRARFLKINQGRLARALEGLSTRQQQVLTLLPLFFHVNHPLLPGYVSGNTPAGVSGF 79

Query: 65  TPD-----ETQRHYLNELELYRGMSVQ----DPPKGELPITGVYTMGSTSSVGQSCSSDL 115
            PD     E QR       L R  + +    +PP+   PI G++ MGS  ++ Q+  SD+
Sbjct: 80  EPDTELLAEAQR-------LTRSFTYKARHGNPPQ---PIHGLFLMGSLGTLAQAEQSDM 129

Query: 116 DIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGS-LGGEDC 174
           D+WVCH   LD +    L+RKC LLE+WAA+ G E   FLI+   F   E  S L  +DC
Sbjct: 130 DLWVCHAPGLDEQALAELRRKCQLLEDWAATQGAEAHLFLIEPQGFVQGERDSRLSSDDC 189

Query: 175 GSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGG 234
           G+TQH LLLDEFYRTA+ LAG+  LW +VP  +E +Y DY  TL ++  +   + LDLG 
Sbjct: 190 GTTQHYLLLDEFYRTALWLAGRTPLWWLVPVYQEHNYRDYTQTLLSKRFIRVTDALDLGH 249

Query: 235 LSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEI 294
           L+ + A EY GA LWQLYK IDSPYK++LK LL E Y+ E+P+ R L+ D KQ +    +
Sbjct: 250 LAHIPAGEYVGAGLWQLYKGIDSPYKSLLKLLLTETYASEHPHVRCLSLDFKQAVFANRL 309

Query: 295 VSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEK---LSRERACVGWRRAVL 351
               LDPY M+  R+ +YL    +  RL+LVRR  YLKV +K   L R R  VGW+R +L
Sbjct: 310 DLDELDPYVMVYRRIEQYLLRRGETARLELVRRSLYLKVNKKLGGLGRSRN-VGWQRQLL 368

Query: 352 SQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSAS 411
           ++L  EWGWDE +LA+LD+R+ WK+ QV     EL+  +  SYR L +FAR  N +  A 
Sbjct: 369 ARLAEEWGWDERQLALLDSRSQWKVRQVAVERRELVAELNHSYRFLTQFAREQNANSRAD 428

Query: 412 PQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVP----PGRANRSGWYLY 467
            +D+ VL R+LYAAFE   GK+ ++NP I+PDL+E  LT +  P    PG  +   W LY
Sbjct: 429 QRDLNVLGRRLYAAFERRAGKIEMINPGIAPDLAEDTLTLVQSPNRKEPGTHH---WGLY 485

Query: 468 NRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQ--EMVA 525
           N    +       P++  R L +L+ WA  NG++ S TRL +   G  DL + +   ++ 
Sbjct: 486 NGNLGVHEWEHFSPIKRCRELLELLTWAHRNGVIDSSTRLALH-PGASDLSEFELFNLIG 544

Query: 526 DVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGE 585
            +    PL L   +   L  P     + ++VN+  DP    R+  +     + D  S+  
Sbjct: 545 SLQQSIPLPLETVSEVRLLQPSVADEILLLVNVGVDPLRHHRDLNILMTTERTDSLSYAG 604

Query: 586 NQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQH 645
            +  LV ++D +  NSWNEV    ++GE ++   L+  L  +   +  P  V V CY  +
Sbjct: 605 VRENLVLTLDQITLNSWNEVLVQRYDGEHALARCLRDFLNSLGHRSHRP-RVRVCCYCHN 663

Query: 646 LRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIE 705
               I  RV+++  + ++L L    Q       L+V+  T  L  +   V++  L     
Sbjct: 664 RAQAISQRVEEIF-DTVQLLLD---QNLNHRYLLQVARHTHVLELQPGQVTLATLVEHDA 719

Query: 706 FYGAISHNKLHGLSVQVETNHVK---LPAVVDGFASEGIIQFFFEETQDENGFNIYILDE 762
               +   +     + ++ N ++   LP V+     +  IQ F+     +   ++Y+LDE
Sbjct: 720 LLATLGEERNSYSPLHLDANALQDYDLPLVLSQGQPQ-CIQVFYRLL--DGWADLYVLDE 776

Query: 763 SN 764
            N
Sbjct: 777 YN 778


>UniRef50_A0Y9E5 Adenylate cyclase, class I n=1 Tax=marine gamma proteobacterium
           HTCC2143 RepID=A0Y9E5_9GAMM
          Length = 966

 Score =  428 bits (1100), Expect = e-118,   Method: Compositional matrix adjust.
 Identities = 277/862 (32%), Positives = 435/862 (50%), Gaps = 44/862 (5%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           ++T+KQR   +N  R+ R  +A+G   Q    LLP + H +HP++PGY+    P G+  +
Sbjct: 20  LKTVKQRFLQVNNARLARTKSALGARQQIFLELLPMMFHVNHPMLPGYVSHQTPCGLDGF 79

Query: 65  TPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSW 124
            P  T++       L R  + +  P     I G++ MGS+ SV QS  SDLDIW+CH   
Sbjct: 80  NP--TKKDVEKTQRLSRSFTYRRQPTMIRRINGIFLMGSSGSVAQSEKSDLDIWLCHPP- 136

Query: 125 LDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLD 184
           +  +E   L++K   +  WAA++G+EV FFL+++ +FR  E  +L  EDCGS+QH LLLD
Sbjct: 137 ISPDETLELKQKTEGISRWAATVGLEVHFFLMEDEKFRLGERETLSTEDCGSSQHYLLLD 196

Query: 185 EFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYF 244
           EFYRT + +AG+  +W ++P DEE+HY+ Y  TL  +  +  +E LD GG+  + A E+ 
Sbjct: 197 EFYRTGLLIAGRIPIWWLIPPDEEKHYEHYAETLRKKRFVRGDETLDFGGVGHIPAGEFI 256

Query: 245 GASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCM 304
           GA +WQLYK+IDSPYK+VLK LL E Y+ EYPN   L+   K+ ++D ++    LDPY +
Sbjct: 257 GAGVWQLYKAIDSPYKSVLKILLTEVYAAEYPNVEPLSTSFKRAIYDNQLDIDELDPYVV 316

Query: 305 MLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSR--ERACVGWRRAVLSQLVSEWGWDE 362
           +  ++  YL A E+F RL+LVRRCFY KV + L+R  +     W+R ++ +LV +W W +
Sbjct: 317 VYRKLESYLLAREEFQRLELVRRCFYFKVGKSLTRSNKDTAKSWQRQLIEKLVGQWNWSD 376

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
           A L  LD R  WK+ QV     +++  +  SYR ++ FARR   +   + Q++ +L RKL
Sbjct: 377 ADLYRLDARNTWKVAQVITEQKQIVRELTNSYRFVLEFARRTRATAMINSQEMTILGRKL 436

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYV-----PPGRANRSGWYLYNRAPNIESII 477
           YAAFE   GK+  +NP I+  L E  LTF  V        +  +  W +         I 
Sbjct: 437 YAAFERKAGKIEWINPGIADSLIEDKLTFYQVQEHQITDAKNQKVFWAVTTEEIKSADIS 496

Query: 478 SHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRL- 535
              P+     L  L+AW  FN LL S TR+ I +G+  V   +LQ MV  +  +      
Sbjct: 497 EDIPVRKADELTTLIAWCHFNSLLDSTTRIAIVEGDHEVSEFELQSMVRSLRQNSATAKQ 556

Query: 536 ----PAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLV 591
                   P     P     + + +N+  DP A  R Q +     + D F +   +  LV
Sbjct: 557 YDNNDDEKPDRFSQPMRPMQIQLFINVGLDPLAHIRTQGIERLSAQTDSFGYSGLRENLV 616

Query: 592 GSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKM---HQDAAPPDSVEVFCYSQHLRG 648
            +V+ +  NSW EV +  ++GE ++I  L   L  +      A P   +  FC ++    
Sbjct: 617 LNVEQVLVNSWGEVSSRRYDGEHALIRCLSDYLQMLPPGSSSALPQLDIRCFCLTRA--S 674

Query: 649 LIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYG 708
            I++RV++L  +      +  R    R+  L +  + + + F     ++ ++    E   
Sbjct: 675 AIKSRVEELFHDITACYYTGNRPANTRY-ILEIQREYYVVQFADNYPTIDRVGTFDELLS 733

Query: 709 AISHNKLHGLSVQVET---NHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNR 765
            +S  +     + ++    N+  L A+    +  G I  F++    ++  +IYILDE   
Sbjct: 734 YLSKPQKSYSPIVLDRYCLNNSPLAAITQ-LSRAGKIHIFYQ--HHKSNADIYILDEKGS 790

Query: 766 VEVYHHCEGSKEELVRDVSRFYSS------SHDRFTYGSSFINFNLPQF----YQI---- 811
           +  Y      +  L+  + +F  S      S +    GSS   FN   F    Y+I    
Sbjct: 791 LLHYTTPFFDERSLLGPLDQFIQSTLFRRASENHDAEGSSLNAFNSDDFTVEYYEITQTV 850

Query: 812 --VKVDGREQVIPFRTKSIGNM 831
             VK+  RE V    T S  N+
Sbjct: 851 SAVKLIRREAVKEIHTGSFFNV 872


>UniRef50_Q2SQ66 Adenylate cyclase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2SQ66_HAHCH
          Length = 971

 Score =  410 bits (1053), Expect = e-112,   Method: Compositional matrix adjust.
 Identities = 262/826 (31%), Positives = 409/826 (49%), Gaps = 28/826 (3%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           ++TL QR   + + R+ R   A+ P  Q V  LLP L H +HPL+PGY+    P  +  Y
Sbjct: 20  LKTLCQRFITLVEHRLQRTRLALTPRQQVVLELLPLLFHVNHPLLPGYVSRTTPHRLVNY 79

Query: 65  TPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSW 124
            PD+        L   R  + ++P +    I  +Y MGST S+  S  SD D+W+CH+  
Sbjct: 80  EPDKNVVAQAQRLS--RSFNYREPARHHGDIASLYLMGSTGSIAHSGGSDFDVWLCHRPD 137

Query: 125 LDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNE-SGSLGGEDCGSTQHILLL 183
           LD+     LQRK  L+  WA  +G E+  FL+D   FR      +   EDCG+ QH LLL
Sbjct: 138 LDAMALMELQRKADLVCQWAMEMGSEMHIFLMDAEAFRSGRHDAAADSEDCGTAQHYLLL 197

Query: 184 DEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEY 243
           DEFYRT + L G   LW ++P D+E  Y D    L  +  + P +++D GG + + + E+
Sbjct: 198 DEFYRTGIWLGGAYPLWWLIPPDQEASYADLAELLLEKRFIKPKDYIDFGGCARIPSNEF 257

Query: 244 FGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYC 303
            GA +WQLYK IDSPYK+VLK +L+E+Y+ E      L+   KQ +    +    LDPY 
Sbjct: 258 VGAGMWQLYKGIDSPYKSVLKLMLVESYAKEEDTLPNLSLAYKQAIFADRLDPDELDPYV 317

Query: 304 MMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS-----RERACVGWRRAVLSQLVSEW 358
           M+  R+ + L +  +  RL+LVRR FYLK+ E+LS     RE++   WRR V+ +L  EW
Sbjct: 318 MVYRRLEQSLQSRREQGRLELVRRSFYLKIGERLSVFVPEREKS---WRRKVMEKLTHEW 374

Query: 359 GWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
            W E  L  LD R+ WK+DQV +    +++ +   YR L  +AR   L+ + S +DI +L
Sbjct: 375 EWSERELRYLDGRSAWKVDQVIQEKRAVVNELTGCYRFLSSYAREKGLAAAISARDINLL 434

Query: 419 TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGR--ANRSGWYLYNRAPNIESI 476
            RKLYAAF+   GKV ++NP I+P+LSE NL F ++      A  +GW LY    N    
Sbjct: 435 GRKLYAAFQRKAGKVEMINPGIAPNLSEDNLAFHHLSSQAIGAAGNGWLLYRNLSNPMDA 494

Query: 477 ISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRL 535
             +  ++ +  L +L+ WA+ NGLL   T + +  G       +LQ++++ +     L L
Sbjct: 495 AFNPAVKRSNSLIELLVWAYCNGLLDRSTSVSLASGESHASQYELQQIISSLRSLISLPL 554

Query: 536 PAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVD 595
           PA T +   +   +R   + VN+  DP A    + +H    + D   +   +  LV ++D
Sbjct: 555 PAVTQQDYRAKARLRATLVYVNVGVDPMADLSRRGLHKLSNRNDALGYASERANLVVTLD 614

Query: 596 LLYRNSWNEVRTLHFNGEQSMIEALKTILGKM---HQDAAPPDSVEVFCYSQHLRGLIRT 652
            +  NSWNEV    +    ++++ LK  L  +    Q       + V CY     G I  
Sbjct: 615 QVIINSWNEVMVQRYESGDTLVQCLKNYLAALAESEQFGEGLPQLSVLCYCPTRAGAIAQ 674

Query: 653 RVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISH 712
           RV QL  + +    S   +   R+  L++  + + L F         LE+ +     ++ 
Sbjct: 675 RVNQLFQQVVFCYFSDKERARSRY-ILQMEDRYFVLQFVDDQPRFTALEDYVGLCEFLAQ 733

Query: 713 NKLHGLSVQVETNHVK---LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVY 769
            + H  S+ V+   +    L AV        +  F+  + +     +IY++DE   + VY
Sbjct: 734 PQKHYSSIVVDDYALSEDVLRAVFARMRPHAVQVFYLNQGRIT---DIYVIDEKGSLLVY 790

Query: 770 HHCEGSKEELVRDVSRFYSSSHDRFTYGSSFIN----FNLPQFYQI 811
                    L+  + +F     +R     S  +    F   +FYQ+
Sbjct: 791 RETGSDINVLLGSLKQFLLGVQERKQMHDSLADDGAGFLEVEFYQL 836


>UniRef50_A1SAP9 Adenylate cyclase n=18 Tax=Shewanella RepID=A1SAP9_SHEAM
          Length = 809

 Score =  405 bits (1042), Expect = e-111,   Method: Compositional matrix adjust.
 Identities = 274/829 (33%), Positives = 422/829 (50%), Gaps = 66/829 (7%)

Query: 13  DAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRH 72
           D +N++R+ RALA + P  + +   +P LLH+H P +PGY     P G+  + P E    
Sbjct: 16  DRLNKVRLARALALLSPLKRHLLHAIPLLLHFHGPRIPGYNGHATPCGLAGFEPQEPH-- 73

Query: 73  YLNELELYRGMSVQDPP-KGELP--ITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEE 129
               LE  R +S+  P  + + P  I G+Y MGST S GQ+  SD+D+WV H+  L +++
Sbjct: 74  ----LEAARVLSLGLPSLRADWPYAIEGIYAMGSTGSFGQNPFSDVDVWVIHEPNLSADD 129

Query: 130 RQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGS------LGGEDCGSTQHILLL 183
            Q L  K  LL  W A    EV+F+L+   +FR ++S S      LG E  GS QH LLL
Sbjct: 130 IQALADKLVLLHQWFAGFEFEVNFYLVHPFQFRADKSYSGNGRVRLGVEHSGSAQHWLLL 189

Query: 184 DEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEY 243
           +EFYRT + L GK + W          + D             ++ L LG + SL A EY
Sbjct: 190 EEFYRTQICLGGKPLYW----------WPD---------ARPSSDGLWLGDVQSLPASEY 230

Query: 244 FGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYC 303
           F ASLWQLYK +  P+KA+LK LLLEAY+W YPN   L+  +      G+  S   DPY 
Sbjct: 231 FSASLWQLYKGLVKPHKALLKVLLLEAYAWRYPNTEQLSTRVWLHTTKGDF-STANDPYF 289

Query: 304 MMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEA 363
           ++ E + EYL AIED  RL++VRRCFYLK   +LS  +    WR   +  LVS W W +A
Sbjct: 290 LLYEAIEEYLLAIEDHRRLEIVRRCFYLKCAVRLSHPQQPKDWRYLKMQLLVSAWEWPDA 349

Query: 364 RLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLY 423
            +  LD+  +W   Q++  + +L + M+ SY+ L+RFA  + ++     +D+G+LTRKL+
Sbjct: 350 LIQTLDDCEDWHTGQLQWFNAQLNELMLVSYQKLLRFAANHGVNEGLRVEDLGMLTRKLH 409

Query: 424 AAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLE 483
             F      V+ +NP  S  L EP LT I       +    YLY + P   ++     + 
Sbjct: 410 TCFNEDKHLVSKLNPLWSSRLQEPVLTVITSQSDGTH----YLYRQEPQASALKGEAAVY 465

Query: 484 YNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDL------PKLQEMVADVSHHFPLRLPA 537
               L  L+ WA  N +   +T+ +  G   +         +L+E + D      L++  
Sbjct: 466 VADNLASLLLWACINQVCDDQTQWFSYGERRLGARLAATDKRLREAIKDTE----LKV-- 519

Query: 538 PTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLL 597
            + + L  P   R L ++VNLE+DPT  +  Q V  D    ++FS G  Q  ++GS+D+L
Sbjct: 520 -SKQDLCQPWHYRKLVLVVNLEHDPTPDWPGQEVLVDIMNANLFSLGRKQLNMLGSLDVL 578

Query: 598 YRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQL 657
             NSW E    HF GEQ++++A+  +   + + A   D   + C S  L   +   V  L
Sbjct: 579 SFNSWGEWHAHHFEGEQALLKAMTFLAPGIRRAAGRLDLRTLGC-SARLTFQLELAVHSL 637

Query: 658 VSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHG 717
           + +  +L   ++   T   + LR+  + +GLFF  L V+ + L +A   Y  +S    H 
Sbjct: 638 LKQVAKLSCQASASST-LVQPLRIGNRNYGLFFNTLGVAYEDLADAPSIYKQMSRG--HL 694

Query: 718 LSVQV----ETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCE 773
           LS+      +     +P ++  +A+E +IQ+F      E G +++IL+  N +  Y    
Sbjct: 695 LSIPRPELGDDPFASVPELIQDYATEDVIQYFLRPR--EEGIDVFILNHKNEISHYVQHG 752

Query: 774 GSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIP 822
            + E LV  VS+ ++       +G     FNLPQF+Q+V++ G  +  P
Sbjct: 753 TTVEALVSKVSQQHAFEGLYEMHG----RFNLPQFFQLVRMQGELKAQP 797


>UniRef50_Q1N416 Adenylate cyclase n=1 Tax=Bermanella marisrubri RepID=Q1N416_9GAMM
          Length = 952

 Score =  382 bits (981), Expect = e-104,   Method: Compositional matrix adjust.
 Identities = 250/834 (29%), Positives = 417/834 (50%), Gaps = 34/834 (4%)

Query: 10  QRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDET 69
           +RL A NQ R +R L+A+    +    +LP L H +   +PG++  + P G+  Y P + 
Sbjct: 20  KRLLAYNQYRYERTLSALTERQKHFLDVLPLLYHVNSDKLPGFVGPDCPCGMARYQPSKD 79

Query: 70  QRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEE 129
                + L +  G   Q    G   I  ++ MGS  S+G S  SD DIW+CH S LD E 
Sbjct: 80  VLRSASTLSM--GFQYQQRRMGHPAIRSLFIMGSCGSLGHSGGSDFDIWLCHDSNLDEES 137

Query: 130 RQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRT 189
             LLQ K   +E +A +LG+E+ FFL+D  RF   E   LG EDCGS QH LLLDEFYRT
Sbjct: 138 MALLQNKALEIERYAETLGIELHFFLMDAKRFVRGERNDLGQEDCGSAQHQLLLDEFYRT 197

Query: 190 AVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLW 249
           ++ LAG   +W +VP + E  YDD+V  LY Q   +  + +D GGL+ + A E+ GA +W
Sbjct: 198 SILLAGCYPVWWLVPPEYEHLYDDFVYRLYQQRFASEEDVIDFGGLAEIPAGEFVGAGMW 257

Query: 250 QLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERV 309
           QLYK+I SPYK++LK  L E+Y+  YPN   L+  +K RL D ++    LDPY ++ +++
Sbjct: 258 QLYKAIGSPYKSILKLFLTESYASAYPNHEPLSISLKGRLFDDQVKLEKLDPYLLLYDKL 317

Query: 310 TEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLD 369
            +YL   E+  RL+LVRRC Y K    + +      W+R +L  L+  WGW + +LA LD
Sbjct: 318 EDYLLQREEGERLELVRRCLYFKANIPMGQSTRRKHWKRDLLRPLILNWGWSDGQLAHLD 377

Query: 370 NRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEAL 429
           NR++W +  V E    L++ ++ SY+ L  F R +      S +D+ +L  KLYA F+  
Sbjct: 378 NRSHWHVHIVMEERKHLVNELIHSYKFLSAFGREHEDETMMSAKDMTLLGHKLYATFDRK 437

Query: 430 PGKVTLVNPQISPDLSEPNLTFIYVPPG---RANRSGWYLYNRAPNIESIISHQPLEYNR 486
           PGK+  +NP IS  + E  L+   +      R  +  W LY       +  +  P++ + 
Sbjct: 438 PGKIDFINPGISKHIQEDKLSLHLLRQHVRRRIPQMNWSLYTGIARPGT--TDAPVKRSA 495

Query: 487 YLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRLP-APTPKALY 544
            L +L+ W   N ++   T + + +G       +L+E++        + LP A  P    
Sbjct: 496 NLIELLGWCHVNRIMDRGTNVVMYQGQQHGKDYELKEILNSFQ---TMPLPDAIEPDFNA 552

Query: 545 SPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNE 604
           +P     LA+ VN+  DP + +  + +     + D   F   +  LV ++D L  NSW E
Sbjct: 553 TPVPT-FLALYVNVFVDPMSHYTRRGISKISNRTDSLGFSALKENLVLTIDQLQYNSWRE 611

Query: 605 VRTLHFNGEQSMIEALKTILGKMHQDAAPPDS------VEVFCYSQHLRGLIRTRVQQLV 658
           V +  + G+ +++  ++  L     +A PP S      ++V CY       I  RV++++
Sbjct: 612 VLSTRYEGQNALLRVIEDFL-----NAYPPGSKQDRPEMQVHCYCATRAKAIAARVKEVL 666

Query: 659 SECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGL 718
            E ++L     R    R   L++  Q   +   +    +   E A   +  ++  + H  
Sbjct: 667 EE-MQLCFYGNRIAERRRYVLQIGEQYHLIQMRQGRPMIDHFERAAHLFKKLASPQPHYS 725

Query: 719 SVQVETNHVK--LPAVVDGFASEGIIQFFFEE---TQDENGFNIYILDESNRVEVYHHCE 773
            V +++  +K  +  ++   +  G++Q F+ +    Q +    IY++DE   +  +    
Sbjct: 726 QVVLDSQALKGTILQMICKHSKPGVLQVFYVQEIGQQQQLTAQIYLIDERGSIIRWRTPM 785

Query: 774 GSKEELVRDVSRFYSS---SHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFR 824
            ++  L+  +  F        +R  YG+  +     ++Y+ V++  +E+ +  R
Sbjct: 786 YNEAALINPIHHFLRQVEYRQNRHRYGNKTVRERPIEYYE-VQLPNKEESLRLR 838


>UniRef50_A4BK19 Adenylate cyclase, class I n=1 Tax=Reinekea blandensis MED297
           RepID=A4BK19_9GAMM
          Length = 985

 Score =  382 bits (981), Expect = e-104,   Method: Compositional matrix adjust.
 Identities = 237/722 (32%), Positives = 374/722 (51%), Gaps = 23/722 (3%)

Query: 4   YIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLD-GNVPKGIC 62
           +++   +R   +NQ R+ R    + P  QQ + LLP L H +H  +PGY    +VP GI 
Sbjct: 55  HVQHATERFMTVNQGRLARVREGLQPKQQQCFDLLPLLFHINHESLPGYSSRDDVPFGIS 114

Query: 63  LYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQ 122
            Y P +T       +   RG   +     +  ++ +Y MGS+ S+GQS SSDLDIWVC+ 
Sbjct: 115 NYHPSDTVIRLAQSIT--RGQVGKRVSLTKPALSALYLMGSSGSIGQSTSSDLDIWVCYN 172

Query: 123 SWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILL 182
           S L+  +   LQ K   +  WA+   +EV FFL+D +RF   E  SL GE+CGSTQH+LL
Sbjct: 173 SELNDRDIDRLQTKAEQISVWASGFNLEVHFFLMDAHRFSGGEQQSLTGENCGSTQHVLL 232

Query: 183 LDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEE 242
           LDEFYRT   LAG    W +VP   E  Y   + T+   G +      D G +++L A E
Sbjct: 233 LDEFYRTVQVLAGNIPAWWLVPTAFESEYRSALDTMAYDGYVNDANTTDFGPIATLPAGE 292

Query: 243 YFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPY 302
           + GA +WQ+YK+IDSPYK+VLK +LLE Y+ EYP    LA   K  ++  ++    LDPY
Sbjct: 293 FIGAGMWQIYKAIDSPYKSVLKLILLEIYAREYPAIESLAHQYKSDIYRMKLSLDDLDPY 352

Query: 303 CMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDE 362
            M+  R+  YLT  ++  RL L+RRCFY KV   LS+      WRR ++  L+  WGW +
Sbjct: 353 VMLYRRIESYLTERDEMERLALLRRCFYFKVGLNLSKPTRTYNWRRELMDYLLDSWGWTK 412

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
           + +A LDN   W I++V      L++ +  SYR L  FA  ++ +   S +D+ +L+RKL
Sbjct: 413 STIAHLDNFRAWTIEEVLSERRLLINELTHSYRFLTEFASEHHSTHVMSQRDLLILSRKL 472

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSG--WYLYNRAPNIESIISHQ 480
           +AAF+  PGK+  +   +  DLS   +  +Y    +       W  YNR   +++  S  
Sbjct: 473 HAAFDRRPGKIDFIRIGLDVDLSHEKIR-LYERESKQEPGVFLWAAYNRP--LDADPSPS 529

Query: 481 PLEYNRYLNKLVAWAWFNGLLTSRTR--LYIKGNGIVDLPKLQEMVADVSHHFPLRLPAP 538
           PL+Y++ L + + W+  NGL+++     +Y     I +  +++ ++A +    P  LP  
Sbjct: 530 PLKYSKGLLETLLWSHLNGLISAHLHIPIYPMQQAITEF-EIRMLLASMRQILPTPLPKI 588

Query: 539 TPKALYSPCEIRHLAIIVNLEYDP---TAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVD 595
              + Y P  +  +   +N+  DP    +A   Q +      LD  +  EN   LV S+D
Sbjct: 589 DSNSFYHPAILTKVVCFINVGRDPLHYLSARGLQKISARSNSLDFSALREN---LVLSID 645

Query: 596 LLYRNSWNEVRTLHFNGEQSMIEALKTILGKMH-QDAAPPDSVEVFCYSQHLRGLIRTRV 654
           ++  N+W EV    F  + +M +ALK+++ +++ Q  +    +E  C++Q     I  RV
Sbjct: 646 MVLVNTWGEVVVERFADQDAMTKALKSLINRVNKQTRSGLPIIETVCHNQTRPQAIAKRV 705

Query: 655 QQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLN--VSVQKLENAIEFYGAISH 712
           + L  + +    S    +  RF    +S     + F+ +N   + Q L +  E    + H
Sbjct: 706 KDLFEDALSALCSPMHPKNTRF-VFNLSDNC--ILFQHINRVTNFQTLSDVTELEQHLGH 762

Query: 713 NK 714
            +
Sbjct: 763 EQ 764


>UniRef50_A1TXX4 Adenylate cyclase n=2 Tax=Marinobacter RepID=A1TXX4_MARAV
          Length = 949

 Score =  382 bits (980), Expect = e-104,   Method: Compositional matrix adjust.
 Identities = 257/832 (30%), Positives = 407/832 (48%), Gaps = 26/832 (3%)

Query: 15  INQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDE----TQ 70
           +NQ R  RA +A+    Q V  LLP + H +HP +PGYLDGN P G   YTP +      
Sbjct: 31  VNQQRWQRACSALTYRQQMVLELLPLVFHRNHPALPGYLDGNCPDGFSGYTPGQEVLDAA 90

Query: 71  RHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEER 130
           R Y      YR    + P      +  ++ MGS  ++G S +SDLD+W+CH+  L +   
Sbjct: 91  RRYARSFH-YRDKGTRKPD-----LDSLFLMGSPGTLGHSVASDLDVWLCHRQDLPASGI 144

Query: 131 QLLQRKCSLLENWAASLGVEVSFFLIDENRFRHN-ESGSLGGEDCGSTQHILLLDEFYRT 189
           + L+RK   L  WA  LGVE+  F+     +R   +   + GE+CGS QH LLLDEFYRT
Sbjct: 145 RCLERKAEKLSEWAGGLGVELHVFVFSAADWRAGRQRVEVTGENCGSAQHFLLLDEFYRT 204

Query: 190 AVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLW 249
           ++ LAG+  LW ++P D E  YD     L     +   +++D G +  +   E  GA +W
Sbjct: 205 SIHLAGQYPLWWLIPVDREADYDHCRRQLVECRFIQARDYIDFGAVPDIPPAELPGAGIW 264

Query: 250 QLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERV 309
           QLYK ID+P+KA+LK LL+E Y+ +   P LL+   KQ +H+G I +  LDPY ++ +R+
Sbjct: 265 QLYKGIDAPWKAILKLLLIECYATDRERP-LLSASFKQAVHNGVISADALDPYVLLYQRL 323

Query: 310 TEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVG--WRRAVLSQLVSEWGWDEARLAM 367
            ++L A +   RL+LVRR  YLK    LSR    VG  WR  +L  LV  WGW    L  
Sbjct: 324 EQWLLARDGADRLELVRRSLYLKSGLPLSRA-GMVGDPWRVELLRSLVEGWGWSSEDLGR 382

Query: 368 LDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFE 427
           LD+R  W  ++V      ++  +  SYR L R AR  +   S S  DI +L RKLYAAF+
Sbjct: 383 LDDRQRWCAEEVMGLRRRVVAELTHSYRLLARLAREQDAQASISANDINLLGRKLYAAFQ 442

Query: 428 ALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRY 487
              GKV L+NP + P L+E NL+F +     A   GW LY    +         +     
Sbjct: 443 RKAGKVELINPGLVPSLAEENLSFHHRSEQGAAGDGWLLYRDLEDPSDAFWQPVIRRAGN 502

Query: 488 LNKLVAWAWFNGLLTSRTRLYIK-GNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSP 546
           L +L+ W + NGLL+  TRL ++ G  +  + +L+E++  ++   P+ +P    +AL   
Sbjct: 503 LAELLVWCYCNGLLSRSTRLNVRAGQSVASVSELKEILDVLAGFLPVPMPPAPRQALSRA 562

Query: 547 CEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVR 606
                  +++N+  DP A    + +H    + D   F   ++ LV ++D +  NSW+EV 
Sbjct: 563 VRPLRNLLLLNVAVDPQAHLTERGLHKLSARNDSLGFSGARDNLVVTIDQITLNSWHEVS 622

Query: 607 TLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRL 666
             H+    ++I+ LK +L ++  + A    + V   S+     I  RV +L ++ +    
Sbjct: 623 LQHYAAGDTLIQCLKNVLAQVAINPAELPDIRVMAPSRGHGQAIARRVSELFADVLRQFF 682

Query: 667 SSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNH 726
           +           + +  + + L F         L++      A+   +   L V  +   
Sbjct: 683 AGGTGPHPLRYIIEMDQRYFLLQFNGQEPGFVALDSRAALMDALFQPQDSFLPVVPDRYA 742

Query: 727 VK----LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRD 782
           ++    L AV +  +  G IQ F++   D+    ++++DE   +         +  L+  
Sbjct: 743 LQDAPLLKAVCEA-SEAGNIQVFWQLQGDQG--QLWVVDEYGSLWHRQLKAQQRRHLLAP 799

Query: 783 VSRFYSSSHDR--FTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMP 832
           + RF  S  +R       +       + Y++V+ DGR    P R + +  MP
Sbjct: 800 LLRFLDSVIERRQLRQADNLEPVAGIRCYELVRRDGRWLADP-RPELVAGMP 850


>UniRef50_UPI00019102CE adenylate cyclase n=2 Tax=Salmonella enterica subsp. enterica
           serovar Typhi RepID=UPI00019102CE
          Length = 186

 Score =  380 bits (975), Expect = e-103,   Method: Compositional matrix adjust.
 Identities = 180/186 (96%), Positives = 182/186 (97%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPSG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           IC YTPDETQRHYLNELELYRGM+ QDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC
Sbjct: 61  ICFYTPDETQRHYLNELELYRGMTPQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           HQSWLD EERQLLQRKCSLLE+WAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI
Sbjct: 121 HQSWLDGEERQLLQRKCSLLESWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180

Query: 181 LLLDEF 186
           LLLDEF
Sbjct: 181 LLLDEF 186


>UniRef50_Q21EM4 Adenylate cyclase n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21EM4_SACD2
          Length = 954

 Score =  377 bits (968), Expect = e-102,   Method: Compositional matrix adjust.
 Identities = 239/799 (29%), Positives = 400/799 (50%), Gaps = 27/799 (3%)

Query: 8   LKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPD 67
           L++R  +IN  R++R  +A+    Q     LP L H +HP+MPG++  + P  +C + PD
Sbjct: 24  LRKRFLSINTDRLERMRSALNSHQQLCLDALPLLFHTNHPMMPGFVSRSTPARLCNFKPD 83

Query: 68  ETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDS 127
           +        +   R  ++   P  E  I G+Y MGS  ++ QS SSDLDIW+CH+  L  
Sbjct: 84  KDILQLGRRVA--RSFTLGYDPSLEEDIYGIYVMGSVGTIAQSESSDLDIWLCHKPGLSK 141

Query: 128 EERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFY 187
           +    L++KC+ +  WA SL +E+ FF +D   F+     +L  E  GS Q +LLLDEFY
Sbjct: 142 QAVDELEKKCTKISEWAMSLRLEMHFFTMDYEEFKRGTLSALNEESSGSAQRLLLLDEFY 201

Query: 188 RTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGAS 247
           R+A+ L G+  LW  VP   E+ Y++Y  TL  +  L+ N  LD G ++++   E+ GA 
Sbjct: 202 RSAIFLGGRIPLWWFVPARAEKDYENYSSTLLDKRFLSDNLVLDFGDIATIPDGEFIGAG 261

Query: 248 LWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLE 307
           +WQLYK+I+SPYK+VLK LLLEAY  E+PN   L+   K+ +  GE+    LD Y ++  
Sbjct: 262 IWQLYKAIESPYKSVLKLLLLEAYVSEHPNIDPLSLSFKREVFAGEVDINNLDSYLIIYR 321

Query: 308 RVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSR--ERACVGWRRAVLSQLVSEWGWDEARL 365
           R+  YL   + + RL+L RRCFY KV + LSR        W+R ++ QLV +W W EA +
Sbjct: 322 RIERYLQQKQQYKRLELARRCFYFKVNKPLSRPSRSNTKSWQRVLMEQLVKDWEWSEADI 381

Query: 366 AMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAA 425
           A+LD R  WK + V    ++L+  +  SYR L+ FA    ++ + S  ++ +L RKL AA
Sbjct: 382 ALLDKRKRWKTNTVAMERSQLVSELNHSYRFLLDFANNCGVAHAISSDELNILGRKLQAA 441

Query: 426 FEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYN 485
           FE  PGK+  +NP IS DLSEP L  ++     A ++  +              + ++ +
Sbjct: 442 FERRPGKIDWINPGISHDLSEP-LIALHSEYEEALKTTLWTAVTFDEDSPNAGGEAIKAS 500

Query: 486 RYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPL---RLPAPTPKA 542
             + +L+ W ++NGL+ + TR  + G   ++  +L+ ++       P     LP  T K 
Sbjct: 501 PSVVELMLWCYYNGLIDNSTRFDLTGCEEINEYELRRLLNLFQQWLPQTTSSLPHETFKQ 560

Query: 543 LYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSW 602
              P +     +++N+   P +  ++        + D   +      LV SVD++ RNSW
Sbjct: 561 SAVPSDA---MLLINVAKHPMSQLQDHGYQRLSSRSDALRYSGFDENLVVSVDIVIRNSW 617

Query: 603 NEVRTLHFNGEQSMIEALKTIL-----GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQL 657
           NE+ T  F  + ++++AL   L     G  H     P ++ V C  + L   I  RV+  
Sbjct: 618 NEINTRRFEKDTALLDALHEYLQLCLPGTHHL----PPALTVECVGETLSNTISQRVKDW 673

Query: 658 VSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHG 717
            +E +    +  +    R+    +    + L F  + +  +   N       +   +   
Sbjct: 674 FNEIVHCFYADKKAANRRY-IFEMGNHYYCLQFSGMKLVTRAFTNPNALLAHLGEEQTKP 732

Query: 718 LSVQVETNHVKLPAV--VDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGS 775
             + +++N + L  +  +        +  F+     + G  I+++DE   +  Y    G 
Sbjct: 733 SPIILDSNALHLHPLRPICSHTKAQSVSVFYHRF--DIGMEIFVVDEKGSIH-YTLLRGC 789

Query: 776 KEE-LVRDVSRFYSSSHDR 793
           K+   ++ + RF  ++ +R
Sbjct: 790 KDHNPLKSLHRFLRATINR 808


>UniRef50_C0ARX6 Putative uncharacterized protein n=1 Tax=Proteus penneri ATCC 35198
           RepID=C0ARX6_9ENTR
          Length = 248

 Score =  372 bits (954), Expect = e-101,   Method: Compositional matrix adjust.
 Identities = 177/223 (79%), Positives = 197/223 (88%), Gaps = 1/223 (0%)

Query: 345 GWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRN 404
           GWRR VLSQLV++W WD  RL +LD R +WKI++VR+AHNELLD MMQSYRNLIRFARRN
Sbjct: 15  GWRRQVLSQLVTQWQWDNERLTILDTRDSWKIERVRDAHNELLDTMMQSYRNLIRFARRN 74

Query: 405 NLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGW 464
           NLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSE +LTFIYVP GRANRSGW
Sbjct: 75  NLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSESHLTFIYVPQGRANRSGW 134

Query: 465 YLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEM 523
           YLYNRAP+ E+I+ HQPLEYNRYLNKLVAW++FNGLLT  +R+YI +G    D  KL E+
Sbjct: 135 YLYNRAPDFENIVGHQPLEYNRYLNKLVAWSYFNGLLTKESRVYIHQGESSCDEIKLHEL 194

Query: 524 VADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF 566
           V D+S HFP+RLPAPTPKALYSPCEIRHLAIIVNLE DPT +F
Sbjct: 195 VRDMSSHFPIRLPAPTPKALYSPCEIRHLAIIVNLETDPTESF 237


>UniRef50_C5BLM3 Adenylate cyclase, class I n=1 Tax=Teredinibacter turnerae T7901
           RepID=C5BLM3_TERTT
          Length = 961

 Score =  355 bits (910), Expect = 6e-96,   Method: Compositional matrix adjust.
 Identities = 252/823 (30%), Positives = 394/823 (47%), Gaps = 58/823 (7%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           +  +++R  AINQ R+ R   A+    Q V   +P L H +HP+MPG+   + P G+C +
Sbjct: 20  LTKIRKRFLAINQDRLTRMRDALTVRQQLVLDAIPLLFHTNHPMMPGFESRDTPAGVCHF 79

Query: 65  TPDETQRHYLNELELYRGM----SVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
              +        ++L RG+    +       E  IT ++ MGS  ++ QS SSDLD W+C
Sbjct: 80  KITK------GAVQLGRGIARSFTASQDAVHEPQITAIFVMGSVGTIAQSESSDLDFWLC 133

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
            +  L  E+ +LL RKC  +  WA    +EV FFL+D   F+  +  +L  E  GS Q +
Sbjct: 134 FKPGLTREQLELLNRKCEKITQWALQCRLEVHFFLMDNAAFKRGQLSALNEESSGSAQRL 193

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLLDEFYRTA+ LAG+  +W  VP   E  YD+Y   L  +  L   + LD GG+ ++  
Sbjct: 194 LLLDEFYRTAIHLAGRTPIWWFVPPGNEHEYDEYTDILQQRRFLNSEDVLDFGGIPTIPD 253

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
            E+ GAS WQLYK I+SPYK+VLK LLLE+Y+ +YPN + L+   K+ ++ GE     LD
Sbjct: 254 SEFLGASRWQLYKGIESPYKSVLKLLLLESYADQYPNIQPLSLVFKEMVYAGEHDIDQLD 313

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERAC--VGWRRAVLSQLVSEW 358
            Y M+   +  YL       RL+L RRCFY KV   L+R        W+  +L  L  EW
Sbjct: 314 SYVMIYRHIERYLQEKNAVRRLELARRCFYFKVNYPLTRSNPNRDKTWQHRLLESLTEEW 373

Query: 359 GWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
           GW    L  LD R  WK   V E  + L + +   ++ L  FA R ++    S ++  +L
Sbjct: 374 GWQRKDLLKLDQRNQWKAPAVHEERSLLKNELSHGFQVLKLFAERYSVEHDISAEEWSIL 433

Query: 419 TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIIS 478
            RKL AAFE  PGK+T +NP IS DL+E  +TF      R       +++   + +  ++
Sbjct: 434 GRKLQAAFETRPGKITWINPGISSDLTEQLVTFAQSAVERPGN----IWSALIHPDGTLT 489

Query: 479 HQP--LEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLP 536
             P  ++ +  L +L  W + N ++   TR  ++    ++   L  ++   ++  PL L 
Sbjct: 490 QNPIHIKTSASLVELYLWCYCNQIVNLTTRYELQQAPHIEERTLHRLLKVFANWLPLPLK 549

Query: 537 APTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVF---SFGENQNCLVGS 593
           +          E      ++N+     A    + +     + D      FGEN   L+ S
Sbjct: 550 SLDHNVFKRSAEPVDALFLLNVGSVAQAGLEQRGIKRLSSQTDALHYSGFGEN---LIIS 606

Query: 594 VDLLYRNSWNEVRTLHFNGEQSMIEALKTIL-----GKMHQDAAPPDSVEVFCYSQHLRG 648
           VDL+ RNSWNE+ T  F+   +++++L+  L     G  H+    P  ++V C S +   
Sbjct: 607 VDLVLRNSWNELTTRRFDSSTALLDSLQDYLKLSLPGSHHR----PPKLQVECVSPNHAN 662

Query: 649 LIRTRVQQLVSECIEL-----RLSSTR---QETGRFKALRVSG-QTWGLFFERLNVSVQK 699
            I TR +  ++E I        +S+TR   +  G F  L+  G +     +  L+  +  
Sbjct: 663 TIATRTRDWLNEIIHCYYGGEYMSATRYVFEMAGLFHILQFKGPRLITRQYPSLDAVLDA 722

Query: 700 LENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASE-------GIIQFFFEETQDE 752
           L +A      I       L       H  L A+    +SE       G I  FF+  QD 
Sbjct: 723 LGDAQPSISPIY------LDSHALVRH-PLKAMCRAISSEGGGRSWAGAIHIFFQRAQDH 775

Query: 753 NGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFT 795
              ++Y++DE   +    +       +++ +  F+ S  DR T
Sbjct: 776 T--DVYVVDEHGSLVHRFYRNSQAVFVLKTLHYFFRSVIDRQT 816


>UniRef50_B3PH57 Adenylate cyclase, class I n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PH57_CELJU
          Length = 651

 Score =  351 bits (901), Expect = 6e-95,   Method: Compositional matrix adjust.
 Identities = 231/629 (36%), Positives = 332/629 (52%), Gaps = 27/629 (4%)

Query: 8   LKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPD 67
           L++R  ++N+ RV R L  +    QQ   LLP L H +HP++PGY+ G  P G+  Y PD
Sbjct: 23  LRRRFLSLNEQRVARTLTNLSERQQQFMQLLPLLFHVNHPMLPGYISGATPAGVYAYQPD 82

Query: 68  ETQRHYLNELELYRGMS-----VQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQ 122
           +      + L L R ++      +D  +    I  ++ MGS  S+  +  SD+DIWVCH 
Sbjct: 83  K------DSLRLARILARSFTYTRDLVETTPGIDALFLMGSVGSIAHTAGSDMDIWVCHN 136

Query: 123 SWLDSEERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHIL 181
             LD    Q L+RKC ++ +WAAS + +EV FFL+    F+  +  S+  E  GS QH L
Sbjct: 137 PTLDLPALQELERKCQVITHWAASQIHLEVHFFLMTGEHFQTGKCSSMSSEASGSAQHYL 196

Query: 182 LLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAE 241
           LLDEFYRTA+ LAGK  LW  VP   E  Y  Y  TL  +  +   E +D GGL  + A 
Sbjct: 197 LLDEFYRTALWLAGKVPLWWFVPVTREADYRRYSETLLHKRFIKAAEVIDFGGLPFIPAN 256

Query: 242 EYFGASLWQLYKSIDSPYKAVLKTLLLEAY----SWEYPNPRLLAKDIKQRLHDGEIVSF 297
           E+ GA +WQLYK+I SPYK+VLK LLLE Y    + +      LA  +K+ L++ E    
Sbjct: 257 EFIGAGIWQLYKAIASPYKSVLKLLLLEVYASGDTAQDTATEPLALSLKRALYEREPDVD 316

Query: 298 GLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRE--RACVGWRRAVLSQLV 355
            LDPY M+ ER+  YL A     RL+LVRRC Y K+ + LSR+  R    W+R +L  L 
Sbjct: 317 RLDPYVMIYERIERYLCARHQDARLELVRRCLYFKINKPLSRKNARTKKSWQRVLLEDLT 376

Query: 356 SEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDI 415
             WGW+  +L MLDNRA WK   V      L++ +  SYR L    ++  L+ + S  ++
Sbjct: 377 HAWGWNSHQLHMLDNRAYWKSPHVIAERALLVNELNHSYRLLAELNKQLGLNAAISTDEL 436

Query: 416 GVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIES 475
            VL RKL+AAFE   GKV  +NP IS +LSEP L F  V         W L   +    +
Sbjct: 437 QVLGRKLHAAFERKAGKVEYINPGISRNLSEPALCF--VQDKSVAGESWQLVRGSQQDLT 494

Query: 476 I--ISHQPLEYNRYLNKLVAWAWFNGLLTSRTR--LYIKGNGIVDLPKLQEMVADVSHHF 531
           +  ++ +P+   R L +L+ W+  NGLL   TR  L  K   I  L K Q+++  +    
Sbjct: 495 LRSVAVEPVRRARSLVELLVWSQVNGLLVPGTRVDLISKDYQITALQK-QQLLQAILQWL 553

Query: 532 PLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLV 591
           P     P  +A  S   +  + ++ NL  +P A    + +     + D   F   +  LV
Sbjct: 554 P-EPHQPEHQAFTSAARVEKVLMLFNLGVEPQAELHKRGMQMLSAQSDPLGFSGFRANLV 612

Query: 592 GSVDLLYRNSWNEVRTLHFNGEQSMIEAL 620
            SVD++  NSW E+   H+  + +++ AL
Sbjct: 613 LSVDIVQLNSWGELVARHYP-QDALVNAL 640


>UniRef50_Q088L2 Adenylate cyclase n=1 Tax=Shewanella frigidimarina NCIMB 400
           RepID=Q088L2_SHEFN
          Length = 819

 Score =  347 bits (889), Expect = 1e-93,   Method: Compositional matrix adjust.
 Identities = 243/834 (29%), Positives = 412/834 (49%), Gaps = 54/834 (6%)

Query: 9   KQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDE 68
           K   + +N +R+ R L  +  +   ++ L+P L+H++   +PG +D + P GI  +T  +
Sbjct: 10  KDLAEKLNGIRLARVLNVLPESQLHLFHLIPFLIHHNQINVPGIIDPDTPCGIHGFTLSD 69

Query: 69  TQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSE 128
                 + L L     +Q     +    G+Y MGST+S GQ+  SD+DIW+ + S L  +
Sbjct: 70  AIVSACDALSLSIPEMIQ---PSDCVFEGIYAMGSTASFGQNPQSDVDIWLVYNSKLTDD 126

Query: 129 ERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRH----NESGSLGGEDCGSTQHILLLD 184
           + +L++ K  L+ +W A    EV+F+L+   +FR     +    +G E  GS+QH LLL+
Sbjct: 127 QLKLIEYKNKLISDWFAGFEFEVNFYLVHPMQFRECSAFDNCQPVGLEHSGSSQHWLLLE 186

Query: 185 EFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYF 244
           EFYR+ +RLAGK + W      +   +D  +              L LG ++SL A EYF
Sbjct: 187 EFYRSHIRLAGKVVAWWPDANSQNTEFDASL--------------LYLGDINSLPAAEYF 232

Query: 245 GASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCM 304
           GASLWQLYK ++ P+KA+LK LLLE Y+ EYP+  L+ + I Q     +  S   D Y +
Sbjct: 233 GASLWQLYKGLNKPHKALLKVLLLETYASEYPSTTLITQQIWQYCEQQDF-SVDNDAYLL 291

Query: 305 MLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS--RERACVGWRRAVLSQLVSEWGWDE 362
           + +R+  YL A  D  RL++VRRCFYLK    LS     +   WR   +  LV +W W  
Sbjct: 292 LYQRIETYLIAQGDDNRLEIVRRCFYLKSGVTLSCLSPNSAADWRVEKIQNLVKQWAWSH 351

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
             +A LDN   W   Q++  + +L + ++ SY+NL++FA +  LS     +++G+L RKL
Sbjct: 352 ELVATLDNSPYWHAGQLKWFNQQLSELLLVSYKNLLQFASKQTLSERMRVEELGLLARKL 411

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRA---PNIESIISH 479
           +  F      +  +N   S   +E +LT  +        S +YLY +A    +    + +
Sbjct: 412 HTYFSEDTHLLQPLNRLWSLSTAEKSLTIFHCRQA----SRFYLYRQAYLDKDPSQAVDN 467

Query: 480 QPL-EYNRY-------LNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHF 531
            P  E++ +       +  LVAW+  NGL T+ T+ +  G G     KL  +   +    
Sbjct: 468 DPAHEFDDHSIHEADNICNLVAWSVLNGLATADTQWFQVGRGKRRTDKLSYLTRKL---I 524

Query: 532 PLRLPAPT--PKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNC 589
           P+    PT   + L  P   + + +I N++ DPT     Q +  +    ++ SFG+ +  
Sbjct: 525 PIMHNVPTVYKRDLCEPWCYQKIVLITNMDRDPTTQLSEQELILEHVNANILSFGQTKIS 584

Query: 590 LVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGL 649
           +V SV ++  NSW E ++  FNG+ +++EA+  I+  + +     D   + C S  L+  
Sbjct: 585 MVSSVAIVCLNSWGEWQSHRFNGKTALLEAISFIILGLKRSNEQVDLSIISC-SAKLKQP 643

Query: 650 IRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGA 709
           I  +++ L+  C  L +    Q       + +  Q + + F  L +  +K++  I   G 
Sbjct: 644 IFNQLKTLLLRCYGL-MKKVNQTNTLMHPITIGEQHYSMHFNSLGMMYRKVD-LITGTGN 701

Query: 710 ISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVY 769
            + + L    +  E  ++  P+V+  F   G  Q+F  E       +++I D++N++E  
Sbjct: 702 FNSSVLPYADL-AEDPYLNSPSVIQKFIVMGAKQYFLRERH--QTLDVFIADDNNQLEHL 758

Query: 770 HHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPF 823
            +   S  + V   S  Y     +         FN+PQF+Q+V ++G+  VIPF
Sbjct: 759 QYQHTSINDFVAKESHLYVFDEQK----QRSPVFNMPQFFQLVDIEGKLTVIPF 808


>UniRef50_D1U0N4 Conserved domain protein n=1 Tax=Yersinia pestis KIM D27
           RepID=D1U0N4_YERPE
          Length = 223

 Score =  282 bits (721), Expect = 5e-74,   Method: Compositional matrix adjust.
 Identities = 132/171 (77%), Positives = 148/171 (86%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLRVDRALAAMGPAFQ+VYSLLP LLH HHP MPGYLDGNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQKVYSLLPILLHCHHPQMPGYLDGNVPHG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           +CL+TP+E Q+ YL ++E   G  +     GELPITGVY+MGSTSS+GQ  +SDLDIWVC
Sbjct: 61  VCLFTPNEIQQDYLADVEARWGEPLAPSAGGELPITGVYSMGSTSSIGQCHTSDLDIWVC 120

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGG 171
           HQ+WLD+EER  LQ+KCSLLE WAAS+GVEVSFFL+DENRFRHN SGSLGG
Sbjct: 121 HQAWLDTEERNQLQQKCSLLEKWAASMGVEVSFFLVDENRFRHNASGSLGG 171


>UniRef50_C4TXU8 Putative uncharacterized protein n=4 Tax=Enterobacteriaceae
           RepID=C4TXU8_YERKR
          Length = 149

 Score =  240 bits (612), Expect = 2e-61,   Method: Compositional matrix adjust.
 Identities = 112/145 (77%), Positives = 128/145 (88%)

Query: 700 LENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYI 759
           +ENA+EFYGAIS+NKLHGLS+QVE + + LP VVDGFASEGIIQFFFE T DE GFNIYI
Sbjct: 1   MENAVEFYGAISNNKLHGLSIQVEADQIHLPPVVDGFASEGIIQFFFEGTADEKGFNIYI 60

Query: 760 LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQ 819
           LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIV++DGR Q
Sbjct: 61  LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVQLDGRTQ 120

Query: 820 VIPFRTKSIGNMPPANQDHDTPLLQ 844
           VIPFR+ ++ ++  A+++   P  Q
Sbjct: 121 VIPFRSNALSHLHIADKETSAPAQQ 145


>UniRef50_C8R2N0 Putative adenylate cyclase n=1 Tax=Desulfurivibrio alkaliphilus
           AHT2 RepID=C8R2N0_9DELT
          Length = 658

 Score =  211 bits (538), Expect = 7e-53,   Method: Compositional matrix adjust.
 Identities = 184/657 (28%), Positives = 321/657 (48%), Gaps = 59/657 (8%)

Query: 16  NQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL-DGNVPKGICLYTPDETQRHYL 74
           N+ R+ +++         +++ +P LLH +HP +PGYL +   P GIC Y P       L
Sbjct: 14  NEERIAKSVLLNPHKSNIIFAAVPYLLHVNHPDLPGYLNEPAAPCGICNYNPATAFSFEL 73

Query: 75  NELELYRGMSVQDPPKGE---LP-----ITGVYTMGSTSSVGQSCSSDLDIWV-CHQSWL 125
                +R    Q  P+GE   LP     I  + T+GS  ++ QS  SD D WV  H+S L
Sbjct: 74  ----FHRFFPGQSVPRGEEKMLPGNLCAIRSLMTIGSVGTIAQSEKSDCDYWVSVHRSQL 129

Query: 126 DSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGED-CGSTQHILLLD 184
            +   +LL  KC+ +  W A  GVE  FFL+D  + R N   S   E+  G++  ILL D
Sbjct: 130 GARGMELLAEKCAAIAAWTAKKGVETHFFLMDIEQTRENSFESAAMEESAGTSLKILLKD 189

Query: 185 EFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEY 243
           E +RT V +AGK +LW  +P   EE+HY   V  L  +  + P++++DLG ++++  EE 
Sbjct: 190 ELFRTHVLVAGKPLLWWFLPPGLEEKHYHGLVKRLVREHKINPDDYVDLGCVATIPREEI 249

Query: 244 FGASLWQLYKSIDSPYKAVLKTLLLE-AYSWEYPNPRLLAKDIK------QRLHDG-EIV 295
           FGA LWQ+ K++DSP+K+V+K   LE     +  +P L +  IK      ++L D  E++
Sbjct: 250 FGACLWQMNKALDSPFKSVIKFAYLELLLQDQQSSPALFSDKIKRLVTYPEKLPDQMEML 309

Query: 296 SFG-LDPYCMML-ERVTEYLTAIEDFTR--LDLVRRCFYLKVCEKL-SRERACVGWR--- 347
             G +DPY ++  E +  Y  A     R   DL+R C +LK  E + S++ A +G +   
Sbjct: 310 DPGEIDPYLLLAREIIAFYQQANNRPIRQWADLIRECLFLKTLEMVESQKHAKMGQKSHH 369

Query: 348 RAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNN-- 405
           +A++ Q+  +W    A      N   W+   +    + +   + ++Y+ L R  +  +  
Sbjct: 370 KAIMEQM-EDWDILPANRQHFLNFRYWQYRDLLAFGSRVHGYLAETYKRLRRVFKEIDPE 428

Query: 406 LSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWY 465
           + ++ S +DI  L RKL+  +E  P K+  +       ++  ++T I++      +  ++
Sbjct: 429 VGLTISERDIATLGRKLFTFYEKKPNKIDYIRSVSRYHMTMEDIT-IHI---TKYQERFF 484

Query: 466 LYNRAPNIE-SIISHQ---PLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGI-VDLPKL 520
            Y    N++ + I  Q    +  + +L +LV W   NG+L   T+L++  N + +DL  +
Sbjct: 485 YYAFQGNLDHNTIREQVGAAIRRDDHLVRLVTWLMVNGMLARHTKLHLTKNFLPIDLADI 544

Query: 521 QEMVADVSHHFPL----RLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFR-------NQ 569
           Q +   +   FP+    ++P   P+ L     I    ++VN   +P    +       ++
Sbjct: 545 QILAEKMLDTFPMVDFSKIP---PQHLVEQENILRALVVVNFFKEPVKGNKTLASTIISE 601

Query: 570 VVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGK 626
             + ++   D  +  + +N L+  +   Y + WN    + F   Q  I A+K +L K
Sbjct: 602 NSYGEYFLHDYNTLAQLKNALLTLLTRHYVSRWNN-NLIVFIPNQDEISAIKNLLEK 657


>UniRef50_Q1NP63 Adenylate cyclase n=2 Tax=delta proteobacterium MLMS-1
           RepID=Q1NP63_9DELT
          Length = 656

 Score =  195 bits (495), Expect = 8e-48,   Method: Compositional matrix adjust.
 Identities = 175/651 (26%), Positives = 301/651 (46%), Gaps = 48/651 (7%)

Query: 16  NQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL-DGNVPKGICLYTP-----DET 69
           N  R+ +++         +++ +P LL  ++  +PGY+ D   P+GIC + P     D  
Sbjct: 14  NAERIAKSMMLNANKSNLIFAAVPYLLQVNNQDLPGYVADPACPRGICDFDPTTLSGDLF 73

Query: 70  QRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWV-CHQSWLDSE 128
           +R +       R   V   P+    I  + T+GS  ++ QS  SD D WV   Q  LD +
Sbjct: 74  RRFFPTAQATAREEMVL--PRSSCAILSLKTIGSIGTIAQSEKSDCDYWVSVDQQQLDGQ 131

Query: 129 ERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLG-GEDCGSTQHILLLDEFY 187
             +LLQ+KC+ +E WA   GVEV FFL+D  + R N   S    E  GS   ILL DE +
Sbjct: 132 GLELLQQKCTAIEEWADKRGVEVHFFLMDITQTRENSFDSAAEDESAGSALKILLKDELF 191

Query: 188 RTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGA 246
           RT V +AGK +LW  +P    E  Y   V  L  +  + P++++DLG ++ +   E FGA
Sbjct: 192 RTHVLVAGKPLLWWFIPPGLNEGQYKALVARLIKERKIDPDDYVDLGYVAGIPKAEIFGA 251

Query: 247 SLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRL---------HDGEIVSF 297
            LWQ+ K++DSP+K+V+K   LE    +  N   L  D  +RL             +V  
Sbjct: 252 CLWQMNKALDSPFKSVIKFAYLELLLQQQQNALPLFSDKVKRLVTYPEKLEDRMEALVPE 311

Query: 298 GLDPYCMMLERVTEYL--TAIEDFTRLD-LVRRCFYLKVCEKL-SRERACVGWRRAVLSQ 353
            +DPY ++   +  +     +E   +   L+R C +LK  E + S+++A +G +  + + 
Sbjct: 312 EVDPYLLLAREIIAFYQQAKLEQMRKWSALIRECLFLKTLEGVESQKQAKMGEKSHLKAL 371

Query: 354 LVSEWGWD---EARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNL----IRFARRNNL 406
           +     WD         LD R  W+  ++    N + + ++++Y+ L     +F     L
Sbjct: 372 MTQMETWDILPAEHQRFLDFRY-WQYKELLALGNRIHEYLIETYKRLRWIFTKFGPDTGL 430

Query: 407 SVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYL 466
           +++   +DI +L RKL+  +E    KV  +       ++  ++T I+V     +R  +Y 
Sbjct: 431 TITE--RDISILGRKLFTFYEKKDNKVEYIRSISRQSMAMEDIT-IHVTK-YDDRFFYYA 486

Query: 467 YNRAPNIESIISHQPLEYNR--YLNKLVAWAWFNGLLTSRTRLYIKGNGI-VDLPKLQEM 523
           +    + E++ +       R   L +L+AW   NG+L S TRL++  N + +DL  +Q +
Sbjct: 487 FQGEQDHETVKTRVEAVIRRDDKLIRLLAWLLVNGMLASHTRLHLTKNFLPIDLVDIQGL 546

Query: 524 VADVSHHFP-LRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFR-------NQVVHFDF 575
              +   FP +   A +P+ L     I    ++VN    P    +        +  + ++
Sbjct: 547 AESMLATFPVVHFSAISPQQLLEQENILRALVVVNFFKQPVKGSKTLPSTIITENSYGEY 606

Query: 576 RKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGK 626
              D  +  + +N L   +   Y + WN      F   Q     +K +LGK
Sbjct: 607 FTHDYQTLTQLKNALRALLTRHYVSRWNNNLEF-FIPHQDEANTIKQMLGK 656


>UniRef50_C0QEU2 CyaA2 n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QEU2_DESAH
          Length = 1302

 Score =  194 bits (493), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 165/639 (25%), Positives = 289/639 (45%), Gaps = 75/639 (11%)

Query: 16   NQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDG--NVPKGICLYTP----DET 69
            N+L +  A+    P    ++ ++P L+H +    PGY       P+GI  Y P     +T
Sbjct: 690  NRLSILTAMDVFKPKQADLFEIIPLLIHENIDF-PGYQADLEQSPRGIAEYRPCKQTVKT 748

Query: 70   QRHYLNELELYRGMSVQDPPKGELP-ITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSE 128
               Y+N  +L    S       ELP + G++TMGST ++ Q+  SD+D WVC + + D E
Sbjct: 749  ASRYVNTGKLECRFS-------ELPHVEGLFTMGSTGTIAQAPDSDIDYWVCVRGY-DPE 800

Query: 129  --ERQLLQRKCSLLENWA-ASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDE 185
              E +  Q+K +LLE WA      E+ FF++D +R R ++ G    E  GS Q ++L +E
Sbjct: 801  CMEEKRFQQKLTLLEQWALGKFKTEIHFFIVDIDRARIDDFGDSTRESSGSAQGMILKEE 860

Query: 186  FYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFG 245
            FYRT + +AGK   W  +P      Y   +++           ++D G +  + +  YFG
Sbjct: 861  FYRTMIHVAGKLPFWCTLPVSVSREYYGLLLSRICANRFQ-CRFIDFGDIHEIPSAAYFG 919

Query: 246  ASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHD-GEIVSFG-LDPYC 303
            AS+WQL+K ++SP+K+V+K  LLE + +     +LL    K +  D G  +  G +DPY 
Sbjct: 920  ASIWQLFKLLESPFKSVIKMALLEEFLYARGKKQLLCNRFKAQWMDPGLYLPLGKIDPYY 979

Query: 304  MMLERVTEYLTAIEDFTRLDLVRRCFYLK--VCEKLSRERACVGWRRAVLSQLVSEWGWD 361
            ++L+ + +Y   + +     LV++CF+LK  + +    +      R   +++ + EW W 
Sbjct: 980  ILLKSLVDYYGQVNNPAAERLVQQCFFLKTGITKDSDLDETLFSMRSFFITRAMDEWAWT 1039

Query: 362  EARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRK 421
               +    N   W+   +     ++   M+++Y  + +   R   ++  +P+D  VL RK
Sbjct: 1040 RKMVFENGNFRQWQYLSITRLSRQIQQYMVKTYIRINQAIDREQCAM-ITPEDRTVLGRK 1098

Query: 422  LYAAFEALPGKV--TLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNR----APNIES 475
            ++  F + PGK+  TL+  +     +   LT++         S W L NR    AP    
Sbjct: 1099 MFVEFSSQPGKIPKTLMVSRSDRHFTSLVLTYL---SQTGKPSQWALVNRFSRSAPESRE 1155

Query: 476  IISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIV----DLPKLQEMVADVSHHF 531
            +I          + ++ AW   N L +  T + +  N       D+  L + +    +H 
Sbjct: 1156 VIRQA-----ETIEEIAAWFIQNQLFSPSTIINLLPNPTPVSSNDIQGLFQALYRFFNHD 1210

Query: 532  PLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLV 591
              +  +P  K L S   I  + I +NL        + + +H                   
Sbjct: 1211 NGK--SPGSKNLLSKARITAIFISINL----CVPRKKRRIH------------------- 1245

Query: 592  GSVDLLYRNSWNEVRTLHFNGEQS------MIEALKTIL 624
                 +Y NSW E+  +  + +Q       ++E LKT+L
Sbjct: 1246 -DSSAIYLNSWGEMFCIRISSQQGFVLRDEILERLKTML 1283


>UniRef50_B4RT26 Adenylate cyclase, class I n=2 Tax=Alteromonas macleodii
           RepID=B4RT26_ALTMD
          Length = 661

 Score =  192 bits (487), Expect = 7e-47,   Method: Compositional matrix adjust.
 Identities = 173/678 (25%), Positives = 296/678 (43%), Gaps = 69/678 (10%)

Query: 16  NQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL-----DGNVPKGICLYT----- 65
           N+ R++RAL  M    + ++ +LP L+H +H  +PG++       +VP GI  Y+     
Sbjct: 24  NKARIERALTLMPEKHRPLFHVLPFLVHVNHESLPGFVAPLSTGESVPFGISNYSFRTDI 83

Query: 66  PDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC-HQSW 124
                R + +E  L+  +  Q  P+ +  +  +  MGS  ++ Q+  SD D WVC     
Sbjct: 84  EKALLRCFPSESHLFADIK-QIWPR-QRAVDALVLMGSVGTIAQTDDSDFDFWVCIDGKQ 141

Query: 125 LDSEERQLLQRKCSLLENWA-ASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLL 183
             S    LLQ+K + +E WA  + G+EV FFL + ++ + N+ G   GE  GS Q + L 
Sbjct: 142 FTSTALSLLQQKLTAIEKWADQTFGIEVHFFLSEIDKVKQNDFGVAEGESAGSAQALFLK 201

Query: 184 DEFYRTAVRLAGKRILWNMVP-CDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEE 242
            EFY T + +AGK   W + P    E+ Y     +L   G    + ++DLG L  L A E
Sbjct: 202 AEFYNTNIVVAGKAPFWWLTPEKTSEKQYQAIYNSLEKGGSPDLDWFMDLGHLEKLDASE 261

Query: 243 YFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVS---FGL 299
            FGA++WQL K++DSP+K+VLK   LE Y       + L   +K+ +H G         +
Sbjct: 262 LFGAAIWQLGKAMDSPFKSVLKMAKLEVYLANIAEGQPLCNLLKKHVHRGAEAPGHVADI 321

Query: 300 DPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSR---ERACVGWRRAVLSQLVS 356
           DPY +M + +  + +       + ++R C YLK    LS+   E     ++R +++    
Sbjct: 322 DPYSLMFDELITHYSEHGQAEDIAVLRECLYLKCGCALSQPLMEDEKPNFKRRIMASYAR 381

Query: 357 EWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIG 416
           +WGW+  +L+  DN+  W   +  +    +   +++ YR + +    +   +    +D+ 
Sbjct: 382 QWGWNRKQLSHFDNQQEWNFSERVQLSRRIHRFLLKCYRRISKELSHHQQVMDE--KDMT 439

Query: 417 VLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIES- 475
           VL R+L   +     K+  +       L    +T I +   +     W  Y  A ++ S 
Sbjct: 440 VLGRRLSTYYAKKADKIEFLRRAFDESLYCEKVT-IAMRQLKNGEEVWSAY--AGDLLSK 496

Query: 476 ---IISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGN-GIVDLPKLQEMVADVSHHF 531
              I   Q +        L+ W   + ++ + +++Y+  N G V    L +++  +  +F
Sbjct: 497 SGIIDESQKITQASSAIALMVWCVSSKIIDTHSKVYLDYNYGEVSELDLNDLLKHLCKYF 556

Query: 532 -PLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCL 590
            P+++ A     L +P  I     IVN    PT                       Q   
Sbjct: 557 PPVKVSALPRNNLLAPERITACFAIVNF---PTL---------------------RQKAT 592

Query: 591 VGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQ-DAAPPDSVEVFCYSQHLRGL 649
           V  V ++Y  SW E         +S  E L T+   + +   APP      CY    RG 
Sbjct: 593 VEDVSVIYSTSWGETFL------KSGSEVLDTLWYDLQEVSPAPP------CYVMVPRGN 640

Query: 650 IRTRVQQLVSECIELRLS 667
            + R+     E  EL  +
Sbjct: 641 QQARILGEFLEAHELNFT 658


>UniRef50_Q2LSY1 Adenylate cyclase n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LSY1_SYNAS
          Length = 653

 Score =  154 bits (388), Expect = 2e-35,   Method: Compositional matrix adjust.
 Identities = 133/445 (29%), Positives = 223/445 (50%), Gaps = 28/445 (6%)

Query: 22  RALAAMGPAFQQVY-SLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELY 80
           R  + + P   ++   LLP +L  +   +PGY+D ++ +   ++   ET++  L    L+
Sbjct: 44  RLFSELAPKDSEIILYLLPWMLSVNDVSIPGYVD-HIKQNFRVFNI-ETEKDILKRERLF 101

Query: 81  R-------GMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC-HQSWLDSEERQL 132
           +        ++V  P +  LP+ G+YT+GS  ++ Q+ SSD D+W+C  ++  D E   L
Sbjct: 102 KKTFHIRNDLTVLKPAEKSLPVEGIYTIGSVGTISQTSSSDCDLWICIDKTLYDEEAFDL 161

Query: 133 LQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAV 191
           L  K   +++W  S L + V FFL D    R    G +  E CGSTQ  +L +EFYRTA+
Sbjct: 162 LTLKIDRIKDWMDSRLKMPVCFFLCDVEDIRACRFGGVDCESCGSTQKKVLKEEFYRTAI 221

Query: 192 RLAGKRILWNMVPCDEEEH--YDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLW 249
             AGK  LW  V  D  +   YDD V   +        + +DLG L  +   E FGA+LW
Sbjct: 222 LTAGKIPLW-WVAWDRRQTLCYDDAVRE-WQSAPSVYYDLIDLGNLDFIDKRESFGAALW 279

Query: 250 QLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDG--EIVSFGLDPYCMMLE 307
           Q  KS+  P K++LK LLL+ +  E P   LL    ++ + D   +  SF +DP    L 
Sbjct: 280 QFNKSLTHPLKSILKMLLLKMFL-ESPKEELLCHRFRRLILDQPRKPHSF-VDPGAFTLI 337

Query: 308 RVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLAM 367
            V ++   ++  T L  + +CFYL+   KL      V    A+  +L   +G D   +  
Sbjct: 338 AVLDFYQNMDPQT-LQFILKCFYLRYKVKLFSRTMTVKEETAL--ELFRRYGLDRETIYE 394

Query: 368 LDNRANWKI-DQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAF 426
           L+  ++W    Q+R     +L  ++  Y+++   AR  +++   + QD+ +L +KL A+ 
Sbjct: 395 LNRFSSWTYSSQIRFGEFIVL-LLVDIYKDIAHIAR--DVTGDVAAQDLTILGQKLSASL 451

Query: 427 EALPGKVTLVNPQISPDLSEPNLTF 451
           +  P K+ +++  +   L  P+LT 
Sbjct: 452 KKKPHKIPVLSKPLET-LKMPSLTL 475


>UniRef50_D1U9E3 Putative adenylate cyclase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
           RepID=D1U9E3_9DELT
          Length = 1291

 Score =  149 bits (376), Expect = 4e-34,   Method: Compositional matrix adjust.
 Identities = 109/330 (33%), Positives = 157/330 (47%), Gaps = 11/330 (3%)

Query: 9   KQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDE 68
           +QR+   N+ R+ RA+  +    Q    +LP LL          L+G  P  +  YTP  
Sbjct: 665 EQRIQGFNRKRLVRAMGRLDRDKQAYLRMLPHLLETDVFETRFTLEGVPPCEVWGYTP-- 722

Query: 69  TQRHYLNELELYRGMSVQDPPKG---ELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWL 125
                L+ +EL R    +  P G    + I  VY MGS  +V Q+  SD+D WVC    +
Sbjct: 723 ----TLSAMELTRQFFPKIRPSGTRARVRILAVYAMGSLGTVAQTAQSDIDCWVCFDGDI 778

Query: 126 DSEERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLD 184
           D      L+RK   L  WA S  G+E  FF +  +  R N   S   E  GS Q +LL +
Sbjct: 779 DPNAEAGLRRKLDALGLWAESEFGIEAHFFPMRMDDVRDNRFSSGDEESSGSAQALLLKE 838

Query: 185 EFYRTAVRLAGKRILWNMVPCDEEE-HYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEY 243
           EFYRTAVR+AGK + W ++P   ++  YD  + +     V+      D G L+ +  +EY
Sbjct: 839 EFYRTAVRIAGKHLAWWVIPAGADKPTYDACIQSARRYPVMGRPRLEDFGHLAPVPPDEY 898

Query: 244 FGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYC 303
           FG SLWQ+ K++ SP+K+VLK  LLE Y+    +P  L   IK+ L      +   DPY 
Sbjct: 899 FGGSLWQMVKAVHSPFKSVLKLGLLETYADPATSPLPLCDRIKRNLFLNRRGTRRTDPYA 958

Query: 304 MMLERVTEYLTAIEDFTRLDLVRRCFYLKV 333
            +   +  Y   + D     L+   F  K 
Sbjct: 959 SLFSTLRAYYADLGDAEAARLLTESFIFKA 988


>UniRef50_C6BYH9 Putative adenylate cyclase n=1 Tax=Desulfovibrio salexigens DSM 2638
            RepID=C6BYH9_DESAD
          Length = 1306

 Score =  148 bits (373), Expect = 1e-33,   Method: Compositional matrix adjust.
 Identities = 138/529 (26%), Positives = 236/529 (44%), Gaps = 27/529 (5%)

Query: 16   NQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLD-GNVPKGICLYTPDETQRHYL 74
            N  R+D A + +    +++  ++P LLH +   +   LD   +   +C Y         L
Sbjct: 692  NSRRLDWAQSKLDSKSRKLLKIIPALLHTNVFEIKSGLDPQTMSSRVCNYALSPQVIKLL 751

Query: 75   NELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQ-SWLDSEERQLL 133
            +E   +  +  +   +   PI    ++GST ++ Q+  SDLD WVC   +   +E RQ L
Sbjct: 752  DEF--FPDIKYEISKESSTPIEAFMSIGSTGTIAQTPDSDLDCWVCCNFTGRSAESRQNL 809

Query: 134  QRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVR 192
              K   +E WA +  G+E+ FF++D    R N  G    E  GS Q  +L +EFYRTAV 
Sbjct: 810  GVKLQAIEKWAMNEFGLEIHFFIMDTREIRDNLFGLSDEESSGSAQSAILKEEFYRTAVL 869

Query: 193  LAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLT-PNEWLDLGGLSSLSAEEYFGASLWQL 251
            LAGK  LW   P +  E    Y  T     +L   N  +DLG + ++  EE+FGASLWQ+
Sbjct: 870  LAGKPPLWWFTPPEAAEKA--YADTKKKVALLKGKNFCVDLGNIPNIPVEEFFGASLWQI 927

Query: 252  YKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTE 311
             K I SP+K+++K  LLE Y+ +     LL + +K+ +  G+     +DPY  + + +  
Sbjct: 928  VKGIKSPFKSIMKFGLLELYTSD-SKYSLLCEKLKKNIISGKRRIRRVDPYMRLYQDLAN 986

Query: 312  YLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVS-EWGWDEARLAMLDN 370
            +  A E    + L      LK C  +S +       RA   +L+              +N
Sbjct: 987  FYRANEKDEYIWLTAMALRLK-CGLVSEKEILSTPSRAEEIELIDFTMKLSGEETGAFEN 1045

Query: 371  RANWK-IDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEAL 429
              +      V E    +   M+ +Y   +R  +     VS +P+D+  L R +++AF   
Sbjct: 1046 FKDLSDFGSVAELGRRVNQFMVNTYMK-VRGEQDKFPGVSITPEDLTRLGRIIFSAFAKR 1104

Query: 430  PGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSG--WYLYNRAPN---IESIISHQPLEY 484
              K+  ++      L  P   F           G  W ++   P+     +I++   +E 
Sbjct: 1105 TNKILRLS------LPGPRTHFFNSINISRTEDGKIWNIHGEYPDESGARNILTR--IES 1156

Query: 485  NRYLNKLVAWAWFNGLLTSRTRLYIK-GNGIVDLPKLQEMVADVSHHFP 532
               LN ++ W   NGL     ++     +G +   +++++ +++   FP
Sbjct: 1157 GPDLNFMLVWLALNGLYNQEMQIKTDISSGPLREREIKKLFSELMRFFP 1205


>UniRef50_C4XU05 Putative uncharacterized protein n=1 Tax=Desulfovibrio magneticus
           RS-1 RepID=C4XU05_DESMR
          Length = 608

 Score =  130 bits (326), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 151/627 (24%), Positives = 255/627 (40%), Gaps = 62/627 (9%)

Query: 46  HPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTS 105
            P     + G VP    L T   T  H+ +     R       P   + I  VYT+GS  
Sbjct: 18  RPAPAARIAGQVPN---LATARLTAAHFGD-----RATEAATLPDDAIRIEAVYTIGSVG 69

Query: 106 SVGQSCSSDLDIWVC-HQSWLDSEERQLLQRKCSLLENWA-ASLGVEVSFFLIDENRFRH 163
           +V Q+  SDLD+WV   ++     +    Q K   +   A     +E+ FFL+  +  R 
Sbjct: 70  TVAQTDDSDLDVWVVLAEADATRPDLPAFQDKLDAVSRQADRDHNLEIHFFLMSVSDIRD 129

Query: 164 NESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQG 222
           N  G    E  GS Q  LL +EFYRTA+ +AGK+  W  +P D  EE Y   +  L    
Sbjct: 130 NIFGYSADEGYGSAQGCLLKEEFYRTALVVAGKKPAWWCLPPDIAEEGYAKAMAALGRTA 189

Query: 223 VLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLA 282
                + LD G + +++ +EYFGASLW + KS+ SP+K+++K  LLE Y+     P LL 
Sbjct: 190 ADVAADCLDFGCVRAIAGDEYFGASLWMIVKSLTSPFKSIIKFGLLEKYAAHPGRPSLLC 249

Query: 283 KDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKV----CEKLS 338
           + +K  +   +   +  DPY ++ + V+ +         ++L+R+ F  K     C++ +
Sbjct: 250 ETLKASILANQGGLWRCDPYALLFKEVSRHYEESGQAGAMELLRQAFLQKTGFDPCDEYA 309

Query: 339 RERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAM----MQSY 394
                     A+L                L  +A  + +        L DA+    +++Y
Sbjct: 310 SRTG-----EAILDHFFPYAPPATGSCPPLPKKAGAEAETGFAQGMVLCDAISNYFLKAY 364

Query: 395 RNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYV 454
             L   +     +   + +D  +L+R++ A+F    GKV  + P + P     +   I +
Sbjct: 365 ERLKNRSAELGAAGGLTERDQAMLSRRIAASFAKRVGKVMRL-PFLRPGRHLFDSLEIGL 423

Query: 455 PPGRANRSGWYLYNRAPNIESII----SHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIK 510
             G+   +G  +    P +          + L     + +L AW   N L   R  L+++
Sbjct: 424 EDGKGREAGLVVRGE-PAVRGGARKSRQKETLRQELSVVRLAAWLVANELY--RPGLHVQ 480

Query: 511 GN---GIVDLPKLQEMVADVSHHFPLRLPAPTPKAL-YSPCEIRHLAIIVNLEYDPTAAF 566
                  + LP    +++ V   FP R     P +   SP ++    ++VN+      A 
Sbjct: 481 ATLLPAPLTLPDCVGLLSAVHDLFPARATFNPPLSWGLSPEKVTAALLVVNM-----TAP 535

Query: 567 RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLH-FNGEQSM-IEALKTIL 624
           R +                       S+D LY  SW E   L    G +S+ I     ++
Sbjct: 536 REERATV-------------------SIDTLYATSWGEFFHLERTTGLESLGISPRDYLI 576

Query: 625 GKMHQDAAPPDSVEVFCYSQHLRGLIR 651
             M     P   ++VF  ++ L   +R
Sbjct: 577 DSMGLTLDPDARIKVFAPAKSLCQAVR 603


>UniRef50_C0N363 Putative uncharacterized protein n=1 Tax=Methylophaga thiooxidans
           DMS010 RepID=C0N363_9GAMM
          Length = 827

 Score =  127 bits (318), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 163/743 (21%), Positives = 313/743 (42%), Gaps = 90/743 (12%)

Query: 48  LMPGYLDGNVPKGICLYTPDETQRHYLNELEL---YRGMSVQDPPKGELPITGVYTMGST 104
           ++PG+++ +VP G+  Y PD+T      ELE    YR  +++       P+ G+Y +   
Sbjct: 1   MLPGFINDDVPAGLIDYQPDKTTLDKAKELETSFKYRRKALR-----RYPLRGLYLIHPQ 55

Query: 105 SSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHN 164
             +  + +  L +W+ H + ++ E+RQ L  K   + +W  + G+ V + L+ E     N
Sbjct: 56  GVLNATDNGPLQLWLLHSNNVNDEQRQGLTLKLDAVVDWMQAAGLTVEYKLLAEADLHTN 115

Query: 165 ESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVL 224
              SL G +         +D  Y + + LAG    W +    E++ Y   +  +  Q +L
Sbjct: 116 ---SLQGWE---------IDLLYHSGMVLAGSVPYWWLSTTAEDQDYQHTINEIKNQRML 163

Query: 225 TPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRL--LA 282
               ++D G  +   AE  F       Y++I +   +    L LE    +     L  L+
Sbjct: 164 NQVSFVDFGAAAPSHAERIFTLC----YQAIKNSLHSGNDWLELEYLHTQLEQDELPCLS 219

Query: 283 KDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSR--E 340
             +KQ++H  ++ S   D   + L ++ ++  A          R   YL   E LS+  +
Sbjct: 220 HLLKQQVHQQKL-SLSHDISHLKLLQIAQHNPASH-------AREALYLVSSELLSKSVK 271

Query: 341 RACVGWRRAVLSQLVSEWGWDEARLAMLDNR---ANWK-IDQVREAHNELLDAMMQSYRN 396
           +A   WRRA +  LV +W W E +L  LD R   AN +  + + E+ + LL  M      
Sbjct: 272 QARYPWRRAFIQSLVEQWNWSEEKLQQLDQRDYAANKRCFELIGESCHRLLKQMTD---- 327

Query: 397 LIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPP 456
              FAR + L V +    +  L +     F+     +  +  Q+ P  S  +  F++   
Sbjct: 328 ---FAREHALEVDSQ---LAELKKCYQLRFKPAADVIDCLPKQMRP-ASNSDRLFLH--- 377

Query: 457 GRANRSGWYL---YNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNG 513
              N S W++     + P   ++  H+ L +      ++AWA  N +L+    L +    
Sbjct: 378 RFQNHSDWFISFQLLQKPTDSALFRHESLLH------VLAWAVSNQILSRSNWLSVNDQ- 430

Query: 514 IVDLPKLQ-EMVADVSHHFPLRLPAPT-----PKALYSPCEIRHLAIIVNLEYDPTAAFR 567
              L K+    V ++S H   R  A +       A   P  I+ + +I NLE   + +  
Sbjct: 431 ---LQKVSTNTVVELSQHVFRRHLADSDLFTHSNAATQPESIQQIMLISNLERQASDSLS 487

Query: 568 NQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKM 627
            Q +    ++ D F++  ++  LV SVD L  ++  +  +   N + + +E L  +L   
Sbjct: 488 QQGLQLSSKQNDPFNYTSSRQSLVLSVDGLLLSNTGQWHSFALNDDHAPLELLIYLLN-W 546

Query: 628 HQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWG 687
              +   +++  +C +      I  R+  L ++    R      + GR   L  +G+ + 
Sbjct: 547 QPSSLTQENISGWCPTPIFGQSITQRLNSLTAQLC--RHYQQFPQHGRL-LLNYAGRAYS 603

Query: 688 LFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFA-SEGIIQFFF 746
           L ++       +   + + + A++ N+           HV  P+ +D +  S+G+  +  
Sbjct: 604 LQWQDNQADYTRRPASQDLWQALAENR-----------HVFTPSALDNYLDSDGLFNYLL 652

Query: 747 EETQDENGFNIYILDESNRVEVY 769
           ++ Q  N  +++I  E N +  Y
Sbjct: 653 QK-QASNSISVFIYLEQNTIICY 674


>UniRef50_D2L1I3 Putative adenylate cyclase n=1 Tax=Desulfovibrio sp. FW1012B
           RepID=D2L1I3_9DELT
          Length = 1281

 Score =  126 bits (316), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 84/284 (29%), Positives = 139/284 (48%), Gaps = 9/284 (3%)

Query: 61  ICLYTPD-ETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWV 119
           I  + PD  T RH +         +  + P   L +  VYT+GS  +V Q+  SDLD+W+
Sbjct: 701 IAGFAPDLPTLRHLVRHFGCP-AAAFPEVPANALAVEAVYTIGSVGTVAQTSDSDLDVWI 759

Query: 120 CHQSWLDSE-ERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGST 177
           C +    +  +      K   +  +A +  G+E+ FF +     R N  G    E  GS 
Sbjct: 760 CLKDGEAAHPDLPAFTDKLETISRFAETEAGLEIHFFCMTVQDVRDNVFGYSEDEGYGSA 819

Query: 178 QHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWLDLGGLS 236
           Q  LL +EFYRTA+ +AG++  W  VP    +E Y   +  +         + LD G ++
Sbjct: 820 QGCLLKEEFYRTALVVAGRKPAWWCVPARIGQEAYAKALSGIRRAEPEVAADCLDFGPVT 879

Query: 237 SLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVS 296
           +++ +EYFGASLW + KS+ SP+K+++K  LLE Y+     P LL   +K  +   +   
Sbjct: 880 AIAGDEYFGASLWMIVKSLTSPFKSIIKFGLLEKYAEHPGEPELLCDTLKDYVFANQGGL 939

Query: 297 FGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKV----CEK 336
           +  DPY ++   V+ +    +    ++L+R+ F  K     CE+
Sbjct: 940 WRCDPYALLFREVSRHYQERKQSGAVELLRQAFLQKTGFDPCEE 983


>UniRef50_A4P0R1 Adenylate cyclase n=2 Tax=Haemophilus influenzae
          RepID=A4P0R1_HAEIN
          Length = 102

 Score = 52.4 bits (124), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 22/45 (48%), Positives = 32/45 (71%)

Query: 9  KQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL 53
          KQ + A++Q R +RAL   G AFQ V +++P LLH +HP +PGY+
Sbjct: 9  KQWVSALDQRRFERALQGSGDAFQHVLAVIPLLLHLNHPQLPGYV 53


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_D2TCR5 CyaA protein n=3 Tax=Erwinia RepID=D2TCR5_ERWPY      1151   0.0  
UniRef50_Q59685 Adenylate cyclase n=330 Tax=cellular organisms R...  1123   0.0  
UniRef50_C4LDV3 Adenylate cyclase n=2 Tax=Gammaproteobacteria Re...   969   0.0  
UniRef50_A1SR20 Adenylate cyclase n=3 Tax=Psychromonas RepID=A1S...   938   0.0  
UniRef50_A0Y9E5 Adenylate cyclase, class I n=1 Tax=marine gamma ...   912   0.0  
UniRef50_Q2SQ66 Adenylate cyclase n=1 Tax=Hahella chejuensis KCT...   894   0.0  
UniRef50_P40134 Adenylate cyclase n=25 Tax=Pasteurellaceae RepID...   875   0.0  
UniRef50_Q21EM4 Adenylate cyclase n=1 Tax=Saccharophagus degrada...   875   0.0  
UniRef50_Q1N416 Adenylate cyclase n=1 Tax=Bermanella marisrubri ...   870   0.0  
UniRef50_A1TXX4 Adenylate cyclase n=2 Tax=Marinobacter RepID=A1T...   867   0.0  
UniRef50_B3H1T6 Adenylate cyclase n=12 Tax=Pasteurellaceae RepID...   849   0.0  
UniRef50_C5BLM3 Adenylate cyclase, class I n=1 Tax=Teredinibacte...   837   0.0  
UniRef50_A4BK19 Adenylate cyclase, class I n=1 Tax=Reinekea blan...   825   0.0  
UniRef50_Q1I310 Adenylate cyclase n=23 Tax=Pseudomonas RepID=Q1I...   821   0.0  
UniRef50_Q088L2 Adenylate cyclase n=1 Tax=Shewanella frigidimari...   767   0.0  
UniRef50_A1SAP9 Adenylate cyclase n=18 Tax=Shewanella RepID=A1SA...   764   0.0  
UniRef50_B3PH57 Adenylate cyclase, class I n=1 Tax=Cellvibrio ja...   694   0.0  
UniRef50_C8R2N0 Putative adenylate cyclase n=1 Tax=Desulfurivibr...   580   e-163
UniRef50_B4RT26 Adenylate cyclase, class I n=2 Tax=Alteromonas m...   579   e-163
UniRef50_Q1NP63 Adenylate cyclase n=2 Tax=delta proteobacterium ...   554   e-156
UniRef50_C0N363 Putative uncharacterized protein n=1 Tax=Methylo...   527   e-148
UniRef50_C0QEU2 CyaA2 n=1 Tax=Desulfobacterium autotrophicum HRM...   522   e-146
UniRef50_C6BYH9 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   518   e-145
UniRef50_C0ARX7 Putative uncharacterized protein n=1 Tax=Proteus...   514   e-144
UniRef50_C4XU05 Putative uncharacterized protein n=1 Tax=Desulfo...   511   e-143
UniRef50_D2L1I3 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   462   e-128
UniRef50_D1U9E3 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   455   e-126
UniRef50_Q2LSY1 Adenylate cyclase n=1 Tax=Syntrophus aciditrophi...   416   e-114
UniRef50_UPI00019102CE adenylate cyclase n=2 Tax=Salmonella ente...   306   2e-81
UniRef50_C0ARX6 Putative uncharacterized protein n=1 Tax=Proteus...   279   2e-73
UniRef50_D1U0N4 Conserved domain protein n=1 Tax=Yersinia pestis...   257   2e-66
UniRef50_C4TXU8 Putative uncharacterized protein n=4 Tax=Enterob...   198   9e-49
UniRef50_A4P0R1 Adenylate cyclase n=2 Tax=Haemophilus influenzae...    64   2e-08

Sequences not found previously or not previously below threshold:

UniRef50_UPI000169845A putative adenylate cyclase n=1 Tax=Endori...    63   4e-08
UniRef50_UPI0001699E12 hypothetical protein Epers_06677 n=1 Tax=...    52   7e-05

>UniRef50_D2TCR5 CyaA protein n=3 Tax=Erwinia RepID=D2TCR5_ERWPY
          Length = 887

 Score = 1151 bits (2978), Expect = 0.0,   Method: Composition-based stats.
 Identities = 698/831 (83%), Positives = 768/831 (92%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           +YLYIETLKQRLDAINQLRVDRALAAMG AFQQVYSLLPTLLHYHHPLMPGYL+GNVP G
Sbjct: 37  LYLYIETLKQRLDAINQLRVDRALAAMGSAFQQVYSLLPTLLHYHHPLMPGYLEGNVPHG 96

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           I  YTPDE+Q  YL+ LE   G     PP GE+P+TGVY+MGSTSSVGQ+ +SDLDIWVC
Sbjct: 97  ISFYTPDESQLSYLHGLEGQSGSDAAVPPHGEMPVTGVYSMGSTSSVGQNGTSDLDIWVC 156

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           HQSWLD++ER  LQ+KC LL+NW   +GVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI
Sbjct: 157 HQSWLDNDERLSLQKKCILLQNWCVEMGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 216

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLLDEFYRTAVR+AGKRILWNMVP +EEE YDDYVM+LY +GVLTPNEWLDLGGL +LSA
Sbjct: 217 LLLDEFYRTAVRMAGKRILWNMVPREEEEQYDDYVMSLYQRGVLTPNEWLDLGGLGTLSA 276

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
           EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP+ RLLA DIKQRLHDGEIVS+GLD
Sbjct: 277 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPDTRLLAMDIKQRLHDGEIVSYGLD 336

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGW 360
           PYCMMLERVT YL  I+D  RLDLVRRCFYLKVCEKLS      GWRR +LSQLV EWGW
Sbjct: 337 PYCMMLERVTRYLIGIDDPARLDLVRRCFYLKVCEKLSLAAENSGWRREILSQLVQEWGW 396

Query: 361 DEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR 420
           D+ RLAMLD+RA WKI QVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR
Sbjct: 397 DKQRLAMLDSRAGWKIGQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR 456

Query: 421 KLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQ 480
           KLYAAFEALPGKVTL+NPQISPDLSE +LTFI+VP GRANR+GWYLYN++P+++SIISHQ
Sbjct: 457 KLYAAFEALPGKVTLLNPQISPDLSESDLTFIHVPNGRANRAGWYLYNQSPDMDSIISHQ 516

Query: 481 PLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTP 540
           PLEYNRYLNKLVAWAWFNGLLTS+TRL+IKGN   DL +LQE+VADV+HHFP+RL APT 
Sbjct: 517 PLEYNRYLNKLVAWAWFNGLLTSKTRLHIKGNESCDLARLQELVADVTHHFPVRLAAPTA 576

Query: 541 KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRN 600
           KALYSPCEIRHLAII+NLE DPTAAFRNQVVHFDFRKLDVFSFG+ Q CLVGSVDLLYRN
Sbjct: 577 KALYSPCEIRHLAIIINLEVDPTAAFRNQVVHFDFRKLDVFSFGQQQQCLVGSVDLLYRN 636

Query: 601 SWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSE 660
           SWNEVRTLHFNGEQSMIEALKTILGKMHQDA+PPDSV+VFCYSQHLRGLIRTRVQQLVSE
Sbjct: 637 SWNEVRTLHFNGEQSMIEALKTILGKMHQDASPPDSVDVFCYSQHLRGLIRTRVQQLVSE 696

Query: 661 CIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSV 720
           C+ELRLSSTRQE GRFKALRV+GQTWGLFFERL+VSVQKLENA+EFYGAIS+NKLHGLS+
Sbjct: 697 CVELRLSSTRQEPGRFKALRVAGQTWGLFFERLSVSVQKLENAVEFYGAISNNKLHGLSL 756

Query: 721 QVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELV 780
           +VE++  +LPAVV+G+ASEGIIQFFFE+T++++GFNIYILDE+NRVEVYHHCEGSKEELV
Sbjct: 757 KVESDQARLPAVVNGYASEGIIQFFFEDTRNDHGFNIYILDETNRVEVYHHCEGSKEELV 816

Query: 781 RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNM 831
           RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIV+V+ R +VIPFR++++  +
Sbjct: 817 RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVQVEERCEVIPFRSQAMTQL 867


>UniRef50_Q59685 Adenylate cyclase n=330 Tax=cellular organisms RepID=CYAA_PROMI
          Length = 865

 Score = 1123 bits (2905), Expect = 0.0,   Method: Composition-based stats.
 Identities = 649/854 (75%), Positives = 729/854 (85%), Gaps = 11/854 (1%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLR++RA A+M   F+QVY L+P LLHYHHP +PGY+ GNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRLERAFASMSDVFKQVYGLIPVLLHYHHPQLPGYIQGNVPHG 60

Query: 61  ICLYTPDETQRHYLNELE-LYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWV 119
            C + PD+ QR ++N+L        +     GELPITG+Y+MGSTSS+GQS  SD+DIWV
Sbjct: 61  TCFFEPDDVQRQWVNKLTNASCDEPMNGYTSGELPITGIYSMGSTSSIGQSHCSDIDIWV 120

Query: 120 CHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQH 179
           CHQSWLD +ER  LQRKC L+E WA  LG++V+FFLIDENRFRH+ SGSLGGEDCGSTQH
Sbjct: 121 CHQSWLDQDERARLQRKCLLIEQWAGELGIDVTFFLIDENRFRHHASGSLGGEDCGSTQH 180

Query: 180 ILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLS 239
           ILLLDEFYRTAVRLAGKR+LW MVP +EE HYD+YV +LYAQGVLTPNEWLDLGGL  LS
Sbjct: 181 ILLLDEFYRTAVRLAGKRLLWTMVPVEEEYHYDEYVNSLYAQGVLTPNEWLDLGGLGELS 240

Query: 240 AEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGL 299
           AEEYFGASLWQLYKS+DSPYKAVLK++LLEAYS +YPN +LLA ++KQ LH GEIV++GL
Sbjct: 241 AEEYFGASLWQLYKSVDSPYKAVLKSILLEAYSADYPNGKLLALEMKQHLHRGEIVNYGL 300

Query: 300 DPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRER---ACVGWRRAVLSQLVS 356
           D YCMMLERVT YL +I D TRLDL+RRCFYLKVCEKLS E+      GWRR VLSQLV+
Sbjct: 301 DAYCMMLERVTRYLVSINDLTRLDLIRRCFYLKVCEKLSNEKNENEPAGWRRQVLSQLVT 360

Query: 357 EWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIG 416
           +W WD  RLA+LDNR +WKI++VR AHNELLD MMQSYRNLIRFARRNNLSVSASPQDIG
Sbjct: 361 QWQWDHERLAILDNRDSWKIERVRNAHNELLDTMMQSYRNLIRFARRNNLSVSASPQDIG 420

Query: 417 VLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESI 476
           VLTRKLYAAFEALPGKVTLVNPQISPDLSEP+LTFIYVPPGRANRSGWYLYNRAP+   I
Sbjct: 421 VLTRKLYAAFEALPGKVTLVNPQISPDLSEPHLTFIYVPPGRANRSGWYLYNRAPDFAHI 480

Query: 477 ISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRL 535
           + HQPLEYNRYLNKLVAW++FNGLLT  +++YI +G+   D  KL E+V D+S HFP+RL
Sbjct: 481 VGHQPLEYNRYLNKLVAWSYFNGLLTKDSQVYIHQGDSSCDEIKLHELVRDISSHFPIRL 540

Query: 536 PAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVD 595
           PAPTPKALYSPCEIRHLAIIVNLE DPT  F +QVVHFDFRKLDVFSFGE + CL+GS+D
Sbjct: 541 PAPTPKALYSPCEIRHLAIIVNLEVDPTERFSDQVVHFDFRKLDVFSFGEEEQCLIGSID 600

Query: 596 LLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQ 655
           LLYRNSWNEVRTLHFNG QSM+E+LKTILGKMHQDAAPP SVEVFCYSQHLRGLIRTRVQ
Sbjct: 601 LLYRNSWNEVRTLHFNGTQSMLESLKTILGKMHQDAAPPASVEVFCYSQHLRGLIRTRVQ 660

Query: 656 QLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKL 715
           QLVSECIELRLS+ R E GRFKALR++GQTWGLFFERLNVSVQKLENAIEFYGAIS+NKL
Sbjct: 661 QLVSECIELRLSTNRLEPGRFKALRIAGQTWGLFFERLNVSVQKLENAIEFYGAISYNKL 720

Query: 716 HGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGS 775
           HGL V++  +   LPAV+DGFA EGIIQFFFE T+D N FNIYILDE+NRVE+Y HCEGS
Sbjct: 721 HGLPVKLGKDARYLPAVIDGFACEGIIQFFFETTEDNNVFNIYILDEANRVEIYSHCEGS 780

Query: 776 KEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMP--- 832
           KEELV+DVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDG  QV+PF   S G +    
Sbjct: 781 KEELVKDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGATQVLPFAGGSFGKLSDLG 840

Query: 833 ---PANQDHDTPLL 843
              P  +    P+ 
Sbjct: 841 KTAPKEEMSTKPIQ 854


>UniRef50_C4LDV3 Adenylate cyclase n=2 Tax=Gammaproteobacteria RepID=C4LDV3_TOLAT
          Length = 830

 Score =  969 bits (2505), Expect = 0.0,   Method: Composition-based stats.
 Identities = 419/835 (50%), Positives = 571/835 (68%), Gaps = 13/835 (1%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           M+   E L  R DAINQ++++RAL AM  A +++ S+LP LLHYHHP +PGY+ G VP G
Sbjct: 1   MFKQFELLVARCDAINQIKMERALEAMNEAGRRMLSMLPVLLHYHHPHLPGYVSGEVPCG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           I  + PD  QR +L      +     +P   E  ++ VYTMGSTSS+GQS  SDLDIW+C
Sbjct: 61  IANFQPDAAQRKFL----FTQCGHTAEPEVKECCLSAVYTMGSTSSIGQSTVSDLDIWIC 116

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           H   L +E R LL++KC  L   A    VE++FFLI EN+FR      +G ++CGS QH+
Sbjct: 117 HDPALSAERRALLEQKCQFLSRLAEQHSVEMNFFLIPENKFRVGNQAQVGLDNCGSAQHL 176

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLL+EFYR+A R+AGKR+LW ++P + E+ YD     L++ G+++ ++WLDLGG+  + A
Sbjct: 177 LLLEEFYRSATRVAGKRLLWPLIPVEREDEYDALAAALFSTGMISEDDWLDLGGVGHIPA 236

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
           EEYFG++LW LYK +DSPYKAVLK L++EAYS E+P+  LLA   K+     +     LD
Sbjct: 237 EEYFGSALWLLYKGLDSPYKAVLKILVMEAYSAEFPHTDLLAVQAKRWFQQHDEFGLSLD 296

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVG--WRRAVLSQLVSEW 358
            Y +ML++VT+YLT + D  RLDL RRCFYLK+C+ LSR        WRR +L +LV +W
Sbjct: 297 AYYLMLDKVTDYLTKLGDTKRLDLARRCFYLKICDPLSRNVPPQHGRWRRDLLVKLVRDW 356

Query: 359 GWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
           GWD A L  LD+   WK++QV+ A+ ELL ++MQSY  LI+FARRNN+S S +P+DIG+L
Sbjct: 357 GWDHATLQHLDSHDQWKVEQVKTAYEELLSSLMQSYSKLIQFARRNNISESINPEDIGIL 416

Query: 419 TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIIS 478
           +RKLY AFEALPGKV  +N +I+PDL E +L+ I VPPG  NR GWYLY  +     II 
Sbjct: 417 SRKLYTAFEALPGKVQRINLKIAPDLHESDLSLIQVPPGHLNRQGWYLYKYSLKPHDIIG 476

Query: 479 HQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGI-VDLPKLQEMVADVSHHFPLRLPA 537
             PLEYN YL+KLVAWA+FNGL+ + TR+ I+  G  +    L +   D++  FP+ LP 
Sbjct: 477 RAPLEYNGYLSKLVAWAYFNGLMVANTRIDIRQAGSDITRTCLHQFCQDLADTFPVELPP 536

Query: 538 PTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLL 597
            +  AL  PCEIRHL I +NLE DPTA +  ++        D+  FG  Q CL+G+VDL+
Sbjct: 537 ASNLALSRPCEIRHLGIFLNLERDPTADWPEEMPPVLEHGEDMLCFGARQECLIGTVDLV 596

Query: 598 YRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQL 657
           YRNSWNEVRTLHFNG  +++EAL TIL KMHQDAA PD+++VFCYSQ+ R  IR +  +L
Sbjct: 597 YRNSWNEVRTLHFNGLDAVVEALSTILSKMHQDAAAPDAIDVFCYSQYYRDEIRHQFTEL 656

Query: 658 VSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHG 717
           V+ CI LRL+  +Q     K L V    + LF ER  VSV++L +AI+FY  +S NKL  
Sbjct: 657 VNSCISLRLALDKQRM--VKLLSVGEHRYALFLERRGVSVRQLSSAIDFYRQVSDNKLER 714

Query: 718 LSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKE 777
            + + + N + +P +VD +ASEG+IQ+FFE+  ++NGFN+YILDE+N+VE+YH   GSKE
Sbjct: 715 QTAEPD-NGLHVPPIVDAYASEGLIQYFFED--NDNGFNVYILDENNKVEIYHEYAGSKE 771

Query: 778 ELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMP 832
           +LV++V+R+Y+ +H RF +    INFNLPQFY++V      QV P+R+ ++  MP
Sbjct: 772 DLVQNVNRYYTMTHQRFDFTEQVINFNLPQFYELVPGSDSLQVTPYRS-AMREMP 825


>UniRef50_A1SR20 Adenylate cyclase n=3 Tax=Psychromonas RepID=A1SR20_PSYIN
          Length = 869

 Score =  938 bits (2425), Expect = 0.0,   Method: Composition-based stats.
 Identities = 383/861 (44%), Positives = 545/861 (63%), Gaps = 36/861 (4%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           I+ L+ + D + +LR+  A   M      V+   P LLHY+HP +PGY  G+ P GI  +
Sbjct: 13  IKRLRDKADELTRLRIQSAELLMNADTLTVFRTFPLLLHYNHPSLPGYTKGDTPTGIHQF 72

Query: 65  TPDETQRHYLNEL-------------------------ELYRGMSVQDPPKGEL---PIT 96
             ++ Q+  L EL                         +L   +S QD P+ +     + 
Sbjct: 73  NVNKKQKKQLAELFPYQEEPQKKAQATNLITKPTDLKIQLNNLLSFQDEPQKKPQQADLI 132

Query: 97  GVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLI 156
           G+Y MGST+S+GQS  SDLDIW+C+   +D +  QLL+ K  L+ +WA   GVE++FFLI
Sbjct: 133 GLYAMGSTASIGQSSESDLDIWICYPHQMDKQRVQLLKNKSWLITHWAEGYGVELNFFLI 192

Query: 157 DENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVM 216
            +N+FR +    +  + CG++QH+LLLDEFYRT + +AGKRILW  VP + E++Y++YV 
Sbjct: 193 PDNKFRIDNKSDMTMDACGTSQHLLLLDEFYRTELHIAGKRILWWQVPFEHEKNYNEYVK 252

Query: 217 TLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP 276
            LY  G L P++WLDLGG   + AEEYFGA+LWQLYK ID+PYKAVLKT+L+EAYSWEYP
Sbjct: 253 KLYDNGGLNPDDWLDLGGFDRIPAEEYFGATLWQLYKGIDTPYKAVLKTILMEAYSWEYP 312

Query: 277 NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEK 336
           N  L+A   K+R  + +     LDPYC+MLE+VT YL  I DF RL++VR CFYLK  E 
Sbjct: 313 NTELIALYYKKRFQEQQTDLEYLDPYCLMLEKVTSYLNKINDFKRLEVVRACFYLKTEEN 372

Query: 337 LSR--ERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSY 394
           LS+        WRR VL++ V+ W W++  +A LDNR  WK+  V  A + LLD +M SY
Sbjct: 373 LSKICTLNPPTWRRQVLTKFVNRWDWNKDHIADLDNRKKWKVRAVSNAKDILLDTLMASY 432

Query: 395 RNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYV 454
             L+RFAR NN+  S S +D+G+L+RKLYAA E+LPGKV L+NP+ISPDLSEP+L+FI V
Sbjct: 433 SKLLRFARDNNIEGSISAEDLGILSRKLYAAHESLPGKVDLINPKISPDLSEPDLSFIQV 492

Query: 455 PPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGI 514
           P  R N +GWYLYN + +  ++I+   L Y +Y+ KLVAW   NGL    T+L++   G 
Sbjct: 493 PKNRKNAAGWYLYNCSLDSFTLINTPTLMYAKYIAKLVAWCHMNGLYEEETQLHLYNQGS 552

Query: 515 -VDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHF 573
            +   KL + + D+   FP+ +P  +  AL  PCEI+HL I +NLE DPT  + +     
Sbjct: 553 DLVDKKLNQFIQDLYSVFPIYIPKASNNALSRPCEIKHLTIFLNLERDPTRHWESTSESE 612

Query: 574 DFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAP 633
           D ++ D+FS+GE++ CL+GS+DL+YRNSWNEVRTLHFN  QS+I+AL TILGKMHQ A P
Sbjct: 613 DDQQGDIFSYGEDKECLIGSIDLIYRNSWNEVRTLHFNSNQSVIDALHTILGKMHQGACP 672

Query: 634 PDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERL 693
           P+ +++FCYS   +  I    +  ++E I+LRL S  Q +   + L+   + +  +FE+ 
Sbjct: 673 PEQIDLFCYSCQFQAQISQAFKSKLNEYIQLRLDSLSQRS--VQTLKTGEENFAFYFEQT 730

Query: 694 NVSVQKLENAIEFYGAISHNKLHGLSVQVETNHV-KLPAVVDGFASEGIIQFFFEETQDE 752
            VSVQ L+N ++ Y  IS+ K+   ++ ++  +  K  +++    SEGI+QFFFE   D 
Sbjct: 731 GVSVQHLKNLVDIYSHISNKKVSNSALNLKNTYFDKTVSIIGSHISEGIVQFFFENYHD- 789

Query: 753 NGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIV 812
            GFN+YI +  N +E  H   G K++LV++V+RFY+S+++        INFNLPQFY+I 
Sbjct: 790 -GFNVYIANADNEIETLHSFTGGKDDLVQNVNRFYASNNNEMNKQDDRINFNLPQFYEIE 848

Query: 813 KVDGREQVIPFRTKSIGNMPP 833
             D +E ++   T +     P
Sbjct: 849 LSDNKELILSSFTSTTKENEP 869


>UniRef50_A0Y9E5 Adenylate cyclase, class I n=1 Tax=marine gamma proteobacterium
           HTCC2143 RepID=A0Y9E5_9GAMM
          Length = 966

 Score =  912 bits (2358), Expect = 0.0,   Method: Composition-based stats.
 Identities = 273/866 (31%), Positives = 435/866 (50%), Gaps = 39/866 (4%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           ++T+KQR   +N  R+ R  +A+G   Q    LLP + H +HP++PGY+    P G+  +
Sbjct: 20  LKTVKQRFLQVNNARLARTKSALGARQQIFLELLPMMFHVNHPMLPGYVSHQTPCGLDGF 79

Query: 65  TPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSW 124
            P  T++       L R  + +  P     I G++ MGS+ SV QS  SDLDIW+CH   
Sbjct: 80  NP--TKKDVEKTQRLSRSFTYRRQPTMIRRINGIFLMGSSGSVAQSEKSDLDIWLCHPP- 136

Query: 125 LDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLD 184
           +  +E   L++K   +  WAA++G+EV FFL+++ +FR  E  +L  EDCGS+QH LLLD
Sbjct: 137 ISPDETLELKQKTEGISRWAATVGLEVHFFLMEDEKFRLGERETLSTEDCGSSQHYLLLD 196

Query: 185 EFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYF 244
           EFYRT + +AG+  +W ++P DEE+HY+ Y  TL  +  +  +E LD GG+  + A E+ 
Sbjct: 197 EFYRTGLLIAGRIPIWWLIPPDEEKHYEHYAETLRKKRFVRGDETLDFGGVGHIPAGEFI 256

Query: 245 GASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCM 304
           GA +WQLYK+IDSPYK+VLK LL E Y+ EYPN   L+   K+ ++D ++    LDPY +
Sbjct: 257 GAGVWQLYKAIDSPYKSVLKILLTEVYAAEYPNVEPLSTSFKRAIYDNQLDIDELDPYVV 316

Query: 305 MLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKL--SRERACVGWRRAVLSQLVSEWGWDE 362
           +  ++  YL A E+F RL+LVRRCFY KV + L  S +     W+R ++ +LV +W W +
Sbjct: 317 VYRKLESYLLAREEFQRLELVRRCFYFKVGKSLTRSNKDTAKSWQRQLIEKLVGQWNWSD 376

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
           A L  LD R  WK+ QV     +++  +  SYR ++ FARR   +   + Q++ +L RKL
Sbjct: 377 ADLYRLDARNTWKVAQVITEQKQIVRELTNSYRFVLEFARRTRATAMINSQEMTILGRKL 436

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPG-----RANRSGWYLYNRAPNIESII 477
           YAAFE   GK+  +NP I+  L E  LTF  V        +  +  W +         I 
Sbjct: 437 YAAFERKAGKIEWINPGIADSLIEDKLTFYQVQEHQITDAKNQKVFWAVTTEEIKSADIS 496

Query: 478 SHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRL- 535
              P+     L  L+AW  FN LL S TR+ I +G+  V   +LQ MV  +  +      
Sbjct: 497 EDIPVRKADELTTLIAWCHFNSLLDSTTRIAIVEGDHEVSEFELQSMVRSLRQNSATAKQ 556

Query: 536 ----PAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLV 591
                   P     P     + + +N+  DP A  R Q +     + D F +   +  LV
Sbjct: 557 YDNNDDEKPDRFSQPMRPMQIQLFINVGLDPLAHIRTQGIERLSAQTDSFGYSGLRENLV 616

Query: 592 GSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQ-DAAPPDSVEVFCYSQHLRGLI 650
            +V+ +  NSW EV +  ++GE ++I  L   L  +    ++    +++ C+       I
Sbjct: 617 LNVEQVLVNSWGEVSSRRYDGEHALIRCLSDYLQMLPPGSSSALPQLDIRCFCLTRASAI 676

Query: 651 RTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAI 710
           ++RV++L  +      +  R    R+  L +  + + + F     ++ ++    E    +
Sbjct: 677 KSRVEELFHDITACYYTGNRPANTRY-ILEIQREYYVVQFADNYPTIDRVGTFDELLSYL 735

Query: 711 SHNKLHGLSVQVETNHVKLPAV--VDGFASEGIIQFFFEETQDENGFNIYILDESNRVEV 768
           S  +     + ++   +    +  +   +  G I  F++    ++  +IYILDE   +  
Sbjct: 736 SKPQKSYSPIVLDRYCLNNSPLAAITQLSRAGKIHIFYQ--HHKSNADIYILDEKGSLLH 793

Query: 769 YHHCEGSKEELVRDVSRFYSS------SHDRFTYGSSFINFNLPQF----YQI------V 812
           Y      +  L+  + +F  S      S +    GSS   FN   F    Y+I      V
Sbjct: 794 YTTPFFDERSLLGPLDQFIQSTLFRRASENHDAEGSSLNAFNSDDFTVEYYEITQTVSAV 853

Query: 813 KVDGREQVIPFRTKSIGNMP-PANQD 837
           K+  RE V    T S  N+    +QD
Sbjct: 854 KLIRREAVKEIHTGSFFNVQAIVDQD 879


>UniRef50_Q2SQ66 Adenylate cyclase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2SQ66_HAHCH
          Length = 971

 Score =  894 bits (2311), Expect = 0.0,   Method: Composition-based stats.
 Identities = 260/827 (31%), Positives = 405/827 (48%), Gaps = 22/827 (2%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           ++TL QR   + + R+ R   A+ P  Q V  LLP L H +HPL+PGY+    P  +  Y
Sbjct: 20  LKTLCQRFITLVEHRLQRTRLALTPRQQVVLELLPLLFHVNHPLLPGYVSRTTPHRLVNY 79

Query: 65  TPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSW 124
            PD+          L R  + ++P +    I  +Y MGST S+  S  SD D+W+CH+  
Sbjct: 80  EPDKNVV--AQAQRLSRSFNYREPARHHGDIASLYLMGSTGSIAHSGGSDFDVWLCHRPD 137

Query: 125 LDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSL-GGEDCGSTQHILLL 183
           LD+     LQRK  L+  WA  +G E+  FL+D   FR     +    EDCG+ QH LLL
Sbjct: 138 LDAMALMELQRKADLVCQWAMEMGSEMHIFLMDAEAFRSGRHDAAADSEDCGTAQHYLLL 197

Query: 184 DEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEY 243
           DEFYRT + L G   LW ++P D+E  Y D    L  +  + P +++D GG + + + E+
Sbjct: 198 DEFYRTGIWLGGAYPLWWLIPPDQEASYADLAELLLEKRFIKPKDYIDFGGCARIPSNEF 257

Query: 244 FGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYC 303
            GA +WQLYK IDSPYK+VLK +L+E+Y+ E      L+   KQ +    +    LDPY 
Sbjct: 258 VGAGMWQLYKGIDSPYKSVLKLMLVESYAKEEDTLPNLSLAYKQAIFADRLDPDELDPYV 317

Query: 304 MMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS--RERACVGWRRAVLSQLVSEWGWD 361
           M+  R+ + L +  +  RL+LVRR FYLK+ E+LS         WRR V+ +L  EW W 
Sbjct: 318 MVYRRLEQSLQSRREQGRLELVRRSFYLKIGERLSVFVPEREKSWRRKVMEKLTHEWEWS 377

Query: 362 EARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRK 421
           E  L  LD R+ WK+DQV +    +++ +   YR L  +AR   L+ + S +DI +L RK
Sbjct: 378 ERELRYLDGRSAWKVDQVIQEKRAVVNELTGCYRFLSSYAREKGLAAAISARDINLLGRK 437

Query: 422 LYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPG--RANRSGWYLYNRAPNIESIISH 479
           LYAAF+   GKV ++NP I+P+LSE NL F ++      A  +GW LY    N      +
Sbjct: 438 LYAAFQRKAGKVEMINPGIAPNLSEDNLAFHHLSSQAIGAAGNGWLLYRNLSNPMDAAFN 497

Query: 480 QPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRLPAP 538
             ++ +  L +L+ WA+ NGLL   T + +  G       +LQ++++ +     L LPA 
Sbjct: 498 PAVKRSNSLIELLVWAYCNGLLDRSTSVSLASGESHASQYELQQIISSLRSLISLPLPAV 557

Query: 539 TPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLY 598
           T +   +   +R   + VN+  DP A    + +H    + D   +   +  LV ++D + 
Sbjct: 558 TQQDYRAKARLRATLVYVNVGVDPMADLSRRGLHKLSNRNDALGYASERANLVVTLDQVI 617

Query: 599 RNSWNEVRTLHFNGEQSMIEALKTILGKM---HQDAAPPDSVEVFCYSQHLRGLIRTRVQ 655
            NSWNEV    +    ++++ LK  L  +    Q       + V CY     G I  RV 
Sbjct: 618 INSWNEVMVQRYESGDTLVQCLKNYLAALAESEQFGEGLPQLSVLCYCPTRAGAIAQRVN 677

Query: 656 QLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKL 715
           QL  + +    S   +   R+  L++  + + L F         LE+ +     ++  + 
Sbjct: 678 QLFQQVVFCYFSDKERARSRY-ILQMEDRYFVLQFVDDQPRFTALEDYVGLCEFLAQPQK 736

Query: 716 HGLSVQVETNHVK---LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHC 772
           H  S+ V+   +    L AV        +  F+  + +     +IY++DE   + VY   
Sbjct: 737 HYSSIVVDDYALSEDVLRAVFARMRPHAVQVFYLNQGRIT---DIYVIDEKGSLLVYRET 793

Query: 773 EGSKEELVRDVSRFYSSSHDRFTYGSSFIN----FNLPQFYQIVKVD 815
                 L+  + +F     +R     S  +    F   +FYQ+    
Sbjct: 794 GSDINVLLGSLKQFLLGVQERKQMHDSLADDGAGFLEVEFYQLQPGK 840


>UniRef50_P40134 Adenylate cyclase n=25 Tax=Pasteurellaceae RepID=CYAA_HAEIN
          Length = 843

 Score =  875 bits (2261), Expect = 0.0,   Method: Composition-based stats.
 Identities = 355/850 (41%), Positives = 505/850 (59%), Gaps = 27/850 (3%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           M   +   KQ + A++Q R +RAL   G AFQ V +++P LLH +HP +PGY+  + P G
Sbjct: 1   MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIVPLLLHLNHPQLPGYVI-HAPSG 59

Query: 61  ICLYTPDETQRHYL-NELELYRGMSVQDPPKGE-------LPITGVYTMGSTSSVGQSCS 112
           I  +   + Q+ +L NE  ++         K          PI GVY MGS  S+ Q+ S
Sbjct: 60  IASFLASDYQKKWLTNEYGIHYADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSS 119

Query: 113 SDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFR-HNESGSLGG 171
           SDLD W+C +  L  +E  LL +K   +  WA    VE++F+L+D+ RFR  + +  L  
Sbjct: 120 SDLDTWICVRDGLSLDEYTLLTQKAKRISEWAMQFNVEINFYLMDQQRFRNEHYADPLTI 179

Query: 172 EDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLD 231
           E+ GS Q++LLLDEFYR+AVRLAGK +LW  +  + E+ Y+  V  L  +G + PN+W+D
Sbjct: 180 ENSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVD 239

Query: 232 LGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHD 291
            GGL   SA EYFGASLW LYK IDSPYK+VLK LLLEAYS EYPN  L+A+  K+ L  
Sbjct: 240 FGGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLA 299

Query: 292 GEIVSFGL-DPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAV 350
           G        DPY  +L +VT+YLTA+ +F RLD V RCFY+K  E  +R +A   WR   
Sbjct: 300 GNTNPDHHFDPYIAILAKVTQYLTALSEFKRLDFVHRCFYVKATEDFARYQAN-NWRIRY 358

Query: 351 LSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSA 410
           +  L  EWGW    +  L+ R  WKI  V+E H+ ++  +M SYRNL+ FAR++++  S 
Sbjct: 359 MEILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLMLSYRNLVEFARKHHIHSSV 418

Query: 411 SPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRA 470
            PQDI +L+RKLY AFE LPGKV+L+N QIS +LSE +LTF+ V   +  + GWYL N+ 
Sbjct: 419 VPQDINILSRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQP 478

Query: 471 PNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHH 530
            +       + +EY   LNKLV+WA+FN LLT +T L I     V L  LQ  V ++   
Sbjct: 479 IHHIMFSKERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKN-VTLSTLQRFVTNLRQS 537

Query: 531 FPLRLPAPTPK-ALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNC 589
           FP  +        L + CEIR L I +NL  DPT+     +     R  D+FSFG  +  
Sbjct: 538 FPSTIAKQPKNSDLLNQCEIRSLFIAINLTTDPTSKVEEVLTGISSR--DLFSFGSLEQS 595

Query: 590 LVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGL 649
           LVGS+D  YRN WNE+RTLHF G+ +++ ALK +  K+++    PDS++V+CYS+  R  
Sbjct: 596 LVGSIDFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRPDSIQVYCYSERYRQD 655

Query: 650 IRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAI---EF 706
           +R  V  LV+ C+ +++    Q+  +   LRV+G+ W LFFE   +S+Q++ N     E 
Sbjct: 656 LRQLVMGLVNRCVSIQVGDI-QQPCQTSRLRVAGKNWQLFFEDRGISLQEIGNESVCNEA 714

Query: 707 YGAISHNKLHGLSVQ-VETNHV--KLPAVVDGFASEGIIQFFFEETQDENGFNIYILDES 763
             A+  +++    ++  ETN    + P  +D FASEG +QFFFE+  D + FN+YILDES
Sbjct: 715 ESAVDFDEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSD-HSFNVYILDES 773

Query: 764 NRVEVYHHCEGSKEELVRDVSRFYS---SSHDRFTYGSSFINFNLPQFYQIVKVDGREQV 820
           N +E+Y HC+G K+E VR++++ Y       D+  Y     NFN PQFYQ+        +
Sbjct: 774 NHLEIYRHCDGEKDEKVREINQLYQNAKQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISI 833

Query: 821 IPFRTKSIGN 830
           +PF+ + +  
Sbjct: 834 VPFKFRQMNK 843


>UniRef50_Q21EM4 Adenylate cyclase n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21EM4_SACD2
          Length = 954

 Score =  875 bits (2260), Expect = 0.0,   Method: Composition-based stats.
 Identities = 237/821 (28%), Positives = 402/821 (48%), Gaps = 21/821 (2%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           +  L++R  +IN  R++R  +A+    Q     LP L H +HP+MPG++  + P  +C +
Sbjct: 21  LTLLRKRFLSINTDRLERMRSALNSHQQLCLDALPLLFHTNHPMMPGFVSRSTPARLCNF 80

Query: 65  TPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSW 124
            PD+        +   R  ++   P  E  I G+Y MGS  ++ QS SSDLDIW+CH+  
Sbjct: 81  KPDKDILQLGRRV--ARSFTLGYDPSLEEDIYGIYVMGSVGTIAQSESSDLDIWLCHKPG 138

Query: 125 LDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLD 184
           L  +    L++KC+ +  WA SL +E+ FF +D   F+     +L  E  GS Q +LLLD
Sbjct: 139 LSKQAVDELEKKCTKISEWAMSLRLEMHFFTMDYEEFKRGTLSALNEESSGSAQRLLLLD 198

Query: 185 EFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYF 244
           EFYR+A+ L G+  LW  VP   E+ Y++Y  TL  +  L+ N  LD G ++++   E+ 
Sbjct: 199 EFYRSAIFLGGRIPLWWFVPARAEKDYENYSSTLLDKRFLSDNLVLDFGDIATIPDGEFI 258

Query: 245 GASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCM 304
           GA +WQLYK+I+SPYK+VLK LLLEAY  E+PN   L+   K+ +  GE+    LD Y +
Sbjct: 259 GAGIWQLYKAIESPYKSVLKLLLLEAYVSEHPNIDPLSLSFKREVFAGEVDINNLDSYLI 318

Query: 305 MLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRE--RACVGWRRAVLSQLVSEWGWDE 362
           +  R+  YL   + + RL+L RRCFY KV + LSR        W+R ++ QLV +W W E
Sbjct: 319 IYRRIERYLQQKQQYKRLELARRCFYFKVNKPLSRPSRSNTKSWQRVLMEQLVKDWEWSE 378

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
           A +A+LD R  WK + V    ++L+  +  SYR L+ FA    ++ + S  ++ +L RKL
Sbjct: 379 ADIALLDKRKRWKTNTVAMERSQLVSELNHSYRFLLDFANNCGVAHAISSDELNILGRKL 438

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPL 482
            AAFE  PGK+  +NP IS DLSEP L  ++     A ++  +              + +
Sbjct: 439 QAAFERRPGKIDWINPGISHDLSEP-LIALHSEYEEALKTTLWTAVTFDEDSPNAGGEAI 497

Query: 483 EYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKA 542
           + +  + +L+ W ++NGL+ + TR  + G   ++  +L+ ++       P    +   + 
Sbjct: 498 KASPSVVELMLWCYYNGLIDNSTRFDLTGCEEINEYELRRLLNLFQQWLPQTTSSLPHET 557

Query: 543 LYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSW 602
                      +++N+   P +  ++        + D   +      LV SVD++ RNSW
Sbjct: 558 FKQSAVPSDAMLLINVAKHPMSQLQDHGYQRLSSRSDALRYSGFDENLVVSVDIVIRNSW 617

Query: 603 NEVRTLHFNGEQSMIEALKTILGKMHQDAAP-PDSVEVFCYSQHLRGLIRTRVQQLVSEC 661
           NE+ T  F  + ++++AL   L          P ++ V C  + L   I  RV+   +E 
Sbjct: 618 NEINTRRFEKDTALLDALHEYLQLCLPGTHHLPPALTVECVGETLSNTISQRVKDWFNEI 677

Query: 662 IELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQ 721
           +    +  +    R     +    + L F  + +  +   N       +   +     + 
Sbjct: 678 VHCFYADKKAAN-RRYIFEMGNHYYCLQFSGMKLVTRAFTNPNALLAHLGEEQTKPSPII 736

Query: 722 VETNHVKLPAV--VDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEE- 778
           +++N + L  +  +        +  F+     + G  I+++DE   +  Y    G K+  
Sbjct: 737 LDSNALHLHPLRPICSHTKAQSVSVFYHRF--DIGMEIFVVDEKGSI-HYTLLRGCKDHN 793

Query: 779 LVRDVSRFYSSSHDRFTYGSSFINFN------LPQFYQIVK 813
            ++ + RF  ++ +R     S   F+         FY++ K
Sbjct: 794 PLKSLHRFLRATINR--EARSNPAFSGDFGIFPIHFYELSK 832


>UniRef50_Q1N416 Adenylate cyclase n=1 Tax=Bermanella marisrubri RepID=Q1N416_9GAMM
          Length = 952

 Score =  870 bits (2249), Expect = 0.0,   Method: Composition-based stats.
 Identities = 246/833 (29%), Positives = 414/833 (49%), Gaps = 22/833 (2%)

Query: 6   ETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYT 65
           + + +RL A NQ R +R L+A+    +    +LP L H +   +PG++  + P G+  Y 
Sbjct: 16  QQVVKRLLAYNQYRYERTLSALTERQKHFLDVLPLLYHVNSDKLPGFVGPDCPCGMARYQ 75

Query: 66  PDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWL 125
           P +      + L +  G   Q    G   I  ++ MGS  S+G S  SD DIW+CH S L
Sbjct: 76  PSKDVLRSASTLSM--GFQYQQRRMGHPAIRSLFIMGSCGSLGHSGGSDFDIWLCHDSNL 133

Query: 126 DSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDE 185
           D E   LLQ K   +E +A +LG+E+ FFL+D  RF   E   LG EDCGS QH LLLDE
Sbjct: 134 DEESMALLQNKALEIERYAETLGIELHFFLMDAKRFVRGERNDLGQEDCGSAQHQLLLDE 193

Query: 186 FYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFG 245
           FYRT++ LAG   +W +VP + E  YDD+V  LY Q   +  + +D GGL+ + A E+ G
Sbjct: 194 FYRTSILLAGCYPVWWLVPPEYEHLYDDFVYRLYQQRFASEEDVIDFGGLAEIPAGEFVG 253

Query: 246 ASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMM 305
           A +WQLYK+I SPYK++LK  L E+Y+  YPN   L+  +K RL D ++    LDPY ++
Sbjct: 254 AGMWQLYKAIGSPYKSILKLFLTESYASAYPNHEPLSISLKGRLFDDQVKLEKLDPYLLL 313

Query: 306 LERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARL 365
            +++ +YL   E+  RL+LVRRC Y K    + +      W+R +L  L+  WGW + +L
Sbjct: 314 YDKLEDYLLQREEGERLELVRRCLYFKANIPMGQSTRRKHWKRDLLRPLILNWGWSDGQL 373

Query: 366 AMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAA 425
           A LDNR++W +  V E    L++ ++ SY+ L  F R +      S +D+ +L  KLYA 
Sbjct: 374 AHLDNRSHWHVHIVMEERKHLVNELIHSYKFLSAFGREHEDETMMSAKDMTLLGHKLYAT 433

Query: 426 FEALPGKVTLVNPQISPDLSEPNLTFIYVPPG---RANRSGWYLYNRAPNIESIISHQPL 482
           F+  PGK+  +NP IS  + E  L+   +      R  +  W LY       +  +  P+
Sbjct: 434 FDRKPGKIDFINPGISKHIQEDKLSLHLLRQHVRRRIPQMNWSLYTGIARPGT--TDAPV 491

Query: 483 EYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRLPAPTPK 541
           + +  L +L+ W   N ++   T + + +G       +L+E++       PL   A  P 
Sbjct: 492 KRSANLIELLGWCHVNRIMDRGTNVVMYQGQQHGKDYELKEILNSF-QTMPLP-DAIEPD 549

Query: 542 ALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNS 601
              +P     LA+ VN+  DP + +  + +     + D   F   +  LV ++D L  NS
Sbjct: 550 FNATPV-PTFLALYVNVFVDPMSHYTRRGISKISNRTDSLGFSALKENLVLTIDQLQYNS 608

Query: 602 WNEVRTLHFNGEQSMIEALKTILGKMHQDAAPP-DSVEVFCYSQHLRGLIRTRVQQLVSE 660
           W EV +  + G+ +++  ++  L      +      ++V CY       I  RV++++ E
Sbjct: 609 WREVLSTRYEGQNALLRVIEDFLNAYPPGSKQDRPEMQVHCYCATRAKAIAARVKEVLEE 668

Query: 661 CIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSV 720
            ++L     R    R   L++  Q   +   +    +   E A   +  ++  + H   V
Sbjct: 669 -MQLCFYGNRIAERRRYVLQIGEQYHLIQMRQGRPMIDHFERAAHLFKKLASPQPHYSQV 727

Query: 721 QVETNHVK--LPAVVDGFASEGIIQFFFEE---TQDENGFNIYILDESNRVEVYHHCEGS 775
            +++  +K  +  ++   +  G++Q F+ +    Q +    IY++DE   +  +     +
Sbjct: 728 VLDSQALKGTILQMICKHSKPGVLQVFYVQEIGQQQQLTAQIYLIDERGSIIRWRTPMYN 787

Query: 776 KEELVRDVSRFYSSS---HDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRT 825
           +  L+  +  F        +R  YG+  +     ++Y+ V++  +E+ +  R 
Sbjct: 788 EAALINPIHHFLRQVEYRQNRHRYGNKTVRERPIEYYE-VQLPNKEESLRLRP 839


>UniRef50_A1TXX4 Adenylate cyclase n=2 Tax=Marinobacter RepID=A1TXX4_MARAV
          Length = 949

 Score =  867 bits (2240), Expect = 0.0,   Method: Composition-based stats.
 Identities = 253/839 (30%), Positives = 404/839 (48%), Gaps = 14/839 (1%)

Query: 15  INQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYL 74
           +NQ R  RA +A+    Q V  LLP + H +HP +PGYLDGN P G   YTP +      
Sbjct: 31  VNQQRWQRACSALTYRQQMVLELLPLVFHRNHPALPGYLDGNCPDGFSGYTPGQEVLDAA 90

Query: 75  NELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQ 134
                 R    +D    +  +  ++ MGS  ++G S +SDLD+W+CH+  L +   + L+
Sbjct: 91  RRY--ARSFHYRDKGTRKPDLDSLFLMGSPGTLGHSVASDLDVWLCHRQDLPASGIRCLE 148

Query: 135 RKCSLLENWAASLGVEVSFFLIDENRFRHNE-SGSLGGEDCGSTQHILLLDEFYRTAVRL 193
           RK   L  WA  LGVE+  F+     +R       + GE+CGS QH LLLDEFYRT++ L
Sbjct: 149 RKAEKLSEWAGGLGVELHVFVFSAADWRAGRQRVEVTGENCGSAQHFLLLDEFYRTSIHL 208

Query: 194 AGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYK 253
           AG+  LW ++P D E  YD     L     +   +++D G +  +   E  GA +WQLYK
Sbjct: 209 AGQYPLWWLIPVDREADYDHCRRQLVECRFIQARDYIDFGAVPDIPPAELPGAGIWQLYK 268

Query: 254 SIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYL 313
            ID+P+KA+LK LL+E Y+ +   P LL+   KQ +H+G I +  LDPY ++ +R+ ++L
Sbjct: 269 GIDAPWKAILKLLLIECYATDRERP-LLSASFKQAVHNGVISADALDPYVLLYQRLEQWL 327

Query: 314 TAIEDFTRLDLVRRCFYLKVCEKLSRERAC-VGWRRAVLSQLVSEWGWDEARLAMLDNRA 372
            A +   RL+LVRR  YLK    LSR       WR  +L  LV  WGW    L  LD+R 
Sbjct: 328 LARDGADRLELVRRSLYLKSGLPLSRAGMVGDPWRVELLRSLVEGWGWSSEDLGRLDDRQ 387

Query: 373 NWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGK 432
            W  ++V      ++  +  SYR L R AR  +   S S  DI +L RKLYAAF+   GK
Sbjct: 388 RWCAEEVMGLRRRVVAELTHSYRLLARLAREQDAQASISANDINLLGRKLYAAFQRKAGK 447

Query: 433 VTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLV 492
           V L+NP + P L+E NL+F +     A   GW LY    +         +     L +L+
Sbjct: 448 VELINPGLVPSLAEENLSFHHRSEQGAAGDGWLLYRDLEDPSDAFWQPVIRRAGNLAELL 507

Query: 493 AWAWFNGLLTSRTRLYIK-GNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRH 551
            W + NGLL+  TRL ++ G  +  + +L+E++  ++   P+ +P    +AL        
Sbjct: 508 VWCYCNGLLSRSTRLNVRAGQSVASVSELKEILDVLAGFLPVPMPPAPRQALSRAVRPLR 567

Query: 552 LAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFN 611
             +++N+  DP A    + +H    + D   F   ++ LV ++D +  NSW+EV   H+ 
Sbjct: 568 NLLLLNVAVDPQAHLTERGLHKLSARNDSLGFSGARDNLVVTIDQITLNSWHEVSLQHYA 627

Query: 612 GEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQ 671
              ++I+ LK +L ++  + A    + V   S+     I  RV +L ++ +    +    
Sbjct: 628 AGDTLIQCLKNVLAQVAINPAELPDIRVMAPSRGHGQAIARRVSELFADVLRQFFAGGTG 687

Query: 672 ETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHV---K 728
                  + +  + + L F         L++      A+   +   L V  +   +    
Sbjct: 688 PHPLRYIIEMDQRYFLLQFNGQEPGFVALDSRAALMDALFQPQDSFLPVVPDRYALQDAP 747

Query: 729 LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYS 788
           L   V   +  G IQ F++   D+    ++++DE   +         +  L+  + RF  
Sbjct: 748 LLKAVCEASEAGNIQVFWQLQGDQG--QLWVVDEYGSLWHRQLKAQQRRHLLAPLLRFLD 805

Query: 789 SSHDR--FTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQ 845
           S  +R       +       + Y++V+ DGR    P R + +  MP +  +     +QQ
Sbjct: 806 SVIERRQLRQADNLEPVAGIRCYELVRRDGRWLADP-RPELVAGMPLSGLEVQAVGVQQ 863


>UniRef50_B3H1T6 Adenylate cyclase n=12 Tax=Pasteurellaceae RepID=B3H1T6_ACTP7
          Length = 842

 Score =  849 bits (2193), Expect = 0.0,   Method: Composition-based stats.
 Identities = 338/822 (41%), Positives = 507/822 (61%), Gaps = 25/822 (3%)

Query: 11  RLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQ 70
           R+DA++  R  RALAA  P F+QV+SLLP L+H + P +P Y+  N P GI  +   E Q
Sbjct: 36  RVDALDHFRTQRALAANSPQFEQVFSLLPLLIHTNLPELPAYIK-NAPSGIAAFELSEYQ 94

Query: 71  RHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEER 130
            +YL+EL L   +++++     +   G+Y+MGST ++ Q+  SD+D+W+C+   L++ E 
Sbjct: 95  ANYLSELSLS-HLAIRNSA-DLVAFDGLYSMGSTGTITQTSLSDIDLWLCYSDRLNALEY 152

Query: 131 QLLQRKCSLLENWAASLGVEVSFFLIDENRFRHN-ESGSLGGEDCGSTQHILLLDEFYRT 189
           QL+++K   ++ WA  LGV+VSF+L++   F+ +     +  E  GS QH  LLDEFYR+
Sbjct: 153 QLVEQKLDKIKQWAKRLGVDVSFYLMNPAHFKAHLYHSDVNEEHSGSAQHYFLLDEFYRS 212

Query: 190 AVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLW 249
           A+RLAGKR+LW  +P       D       +     P EW+D G  SSLS  E+FGASLW
Sbjct: 213 AIRLAGKRLLWLHLP-------DGLYQQYLSSAEFNPAEWIDFGDFSSLSTGEFFGASLW 265

Query: 250 QLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERV 309
           QLYK I+ PYK+ +K LLLE+Y+  YPN  L++K  KQ+L   + V +  DPY  MLE+V
Sbjct: 266 QLYKGIEYPYKSAIKILLLESYADTYPNTNLISKQFKQKLLAVQTVEYHFDPYLAMLEQV 325

Query: 310 TEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLD 369
           T+YL+  ++  RL  +R CFY+K  E  SRE     WR   L +L+  W W+   L +LD
Sbjct: 326 TDYLSKRKEMLRLSRLRMCFYVKASEGESRE----TWRTQALRELIEGWNWNLQELNLLD 381

Query: 370 NRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEAL 429
           NR NWKI Q       +++ ++QSYRNLI+FAR+ ++  S    DI +L RKLY+ FE  
Sbjct: 382 NRQNWKIKQAVTHQQIIVEQLLQSYRNLIQFARKFHIDPSILASDIDILMRKLYSVFEMA 441

Query: 430 PGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLN 489
           PGKV L+NPQIS +L+E  +TFI V  G A ++GWY+ N+AP      + + +   + L 
Sbjct: 442 PGKVPLINPQISENLAESAVTFIEVREGSAMQAGWYMINQAPRSPYDPALRYVRQAKNLT 501

Query: 490 KLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEI 549
           KLVAW +FNG++TS T+L++     +DL +L++ + D+   FP++ P      L  P EI
Sbjct: 502 KLVAWGYFNGVITSNTQLHLVSRS-LDLSRLRQFITDLRLSFPVKAPEMIDDDLLHPNEI 560

Query: 550 RHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLH 609
           R L + +NL  DPT     +      +  D+F+FG  Q  LVGSV ++YRN WNE+RT H
Sbjct: 561 RSLILAINLVKDPTQKL--EPTRRAVQPSDLFNFGSAQQSLVGSVSIIYRNLWNEIRTQH 618

Query: 610 FNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSST 669
           F G+ ++++ALK I  K+++ +A P SV VFCYS+HLR  +R  + +LV +CI ++  + 
Sbjct: 619 FEGDDAILKALKLISNKIYRSSASPQSVNVFCYSRHLRSELRDFIAELVHKCITIQTGTI 678

Query: 670 RQETGRFKALRVSGQTWGLFFERLNVSVQKL-ENAIEFYGAISHNKLHGLSVQVETNHVK 728
            Q+      L+V+G+ W   F +  V +Q L E A+EF   I+ N      +  ++N V 
Sbjct: 679 SQKQPL-STLKVAGKMWQFVFGKQKVEIQPLNEQAVEFNQEIA-NLQDEAGMHAKSNCV- 735

Query: 729 LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYS 788
            P  +D FASEG +QFFFE+  DE  FN+YILDE N +EV H C  SKEE V++++R ++
Sbjct: 736 FPKEIDEFASEGFLQFFFEDNADE-SFNVYILDEKNTLEVCHDCFCSKEEKVKEINRIHA 794

Query: 789 SSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGN 830
           + + +    +S  +FN PQFYQ++ ++G+ +++PF++K    
Sbjct: 795 AENSK--ENASLESFNFPQFYQLISLNGKTRIVPFQSKQHRQ 834


>UniRef50_C5BLM3 Adenylate cyclase, class I n=1 Tax=Teredinibacter turnerae T7901
           RepID=C5BLM3_TERTT
          Length = 961

 Score =  837 bits (2162), Expect = 0.0,   Method: Composition-based stats.
 Identities = 241/852 (28%), Positives = 400/852 (46%), Gaps = 28/852 (3%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           +  +++R  AINQ R+ R   A+    Q V   +P L H +HP+MPG+   + P G+C +
Sbjct: 20  LTKIRKRFLAINQDRLTRMRDALTVRQQLVLDAIPLLFHTNHPMMPGFESRDTPAGVCHF 79

Query: 65  TPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSW 124
              +          + R  +       E  IT ++ MGS  ++ QS SSDLD W+C +  
Sbjct: 80  KITKGAVQLGR--GIARSFTASQDAVHEPQITAIFVMGSVGTIAQSESSDLDFWLCFKPG 137

Query: 125 LDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLD 184
           L  E+ +LL RKC  +  WA    +EV FFL+D   F+  +  +L  E  GS Q +LLLD
Sbjct: 138 LTREQLELLNRKCEKITQWALQCRLEVHFFLMDNAAFKRGQLSALNEESSGSAQRLLLLD 197

Query: 185 EFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYF 244
           EFYRTA+ LAG+  +W  VP   E  YD+Y   L  +  L   + LD GG+ ++   E+ 
Sbjct: 198 EFYRTAIHLAGRTPIWWFVPPGNEHEYDEYTDILQQRRFLNSEDVLDFGGIPTIPDSEFL 257

Query: 245 GASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCM 304
           GAS WQLYK I+SPYK+VLK LLLE+Y+ +YPN + L+   K+ ++ GE     LD Y M
Sbjct: 258 GASRWQLYKGIESPYKSVLKLLLLESYADQYPNIQPLSLVFKEMVYAGEHDIDQLDSYVM 317

Query: 305 MLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERAC--VGWRRAVLSQLVSEWGWDE 362
           +   +  YL       RL+L RRCFY KV   L+R        W+  +L  L  EWGW  
Sbjct: 318 IYRHIERYLQEKNAVRRLELARRCFYFKVNYPLTRSNPNRDKTWQHRLLESLTEEWGWQR 377

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
             L  LD R  WK   V E  + L + +   ++ L  FA R ++    S ++  +L RKL
Sbjct: 378 KDLLKLDQRNQWKAPAVHEERSLLKNELSHGFQVLKLFAERYSVEHDISAEEWSILGRKL 437

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQP- 481
            AAFE  PGK+T +NP IS DL+E  +TF      R       +++   + +  ++  P 
Sbjct: 438 QAAFETRPGKITWINPGISSDLTEQLVTFAQSAVERPGN----IWSALIHPDGTLTQNPI 493

Query: 482 -LEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTP 540
            ++ +  L +L  W + N ++   TR  ++    ++   L  ++   ++  PL L +   
Sbjct: 494 HIKTSASLVELYLWCYCNQIVNLTTRYELQQAPHIEERTLHRLLKVFANWLPLPLKSLDH 553

Query: 541 KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRN 600
                  E      ++N+     A    + +     + D   +      L+ SVDL+ RN
Sbjct: 554 NVFKRSAEPVDALFLLNVGSVAQAGLEQRGIKRLSSQTDALHYSGFGENLIISVDLVLRN 613

Query: 601 SWNEVRTLHFNGEQSMIEALKTILG-KMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVS 659
           SWNE+ T  F+   +++++L+  L   +      P  ++V C S +    I TR +  ++
Sbjct: 614 SWNELTTRRFDSSTALLDSLQDYLKLSLPGSHHRPPKLQVECVSPNHANTIATRTRDWLN 673

Query: 660 ECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLS 719
           E I            R+    ++G    L F+   +  ++  +      A+   +     
Sbjct: 674 EIIHCYYGGEYMSATRY-VFEMAGLFHILQFKGPRLITRQYPSLDAVLDALGDAQPSISP 732

Query: 720 VQVETNHV---KLPAVVDGFASE-------GIIQFFFEETQDENGFNIYILDESNRVEVY 769
           + ++++ +    L A+    +SE       G I  FF+  QD    ++Y++DE   +   
Sbjct: 733 IYLDSHALVRHPLKAMCRAISSEGGGRSWAGAIHIFFQRAQDHT--DVYVVDEHGSLVHR 790

Query: 770 HHCEGSKEELVRDVSRFYSSSHDRFTYGSS--FINFN--LPQFYQIVKVDGREQVIPFRT 825
            +       +++ +  F+ S  DR T  +     +F      FY++ +   +  V   + 
Sbjct: 791 FYRNSQAVFVLKTLHYFFRSVIDRQTQLNQQLLHDFGIFPIHFYELKRDSRQCYVSEPKR 850

Query: 826 KSIGNMPPANQD 837
            +  ++ P   +
Sbjct: 851 VANESVVPVELE 862


>UniRef50_A4BK19 Adenylate cyclase, class I n=1 Tax=Reinekea blandensis MED297
           RepID=A4BK19_9GAMM
          Length = 985

 Score =  825 bits (2130), Expect = 0.0,   Method: Composition-based stats.
 Identities = 244/836 (29%), Positives = 401/836 (47%), Gaps = 16/836 (1%)

Query: 4   YIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLD-GNVPKGIC 62
           +++   +R   +NQ R+ R    + P  QQ + LLP L H +H  +PGY    +VP GI 
Sbjct: 55  HVQHATERFMTVNQGRLARVREGLQPKQQQCFDLLPLLFHINHESLPGYSSRDDVPFGIS 114

Query: 63  LYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQ 122
            Y P +T         + RG   +     +  ++ +Y MGS+ S+GQS SSDLDIWVC+ 
Sbjct: 115 NYHPSDTVIRLAQ--SITRGQVGKRVSLTKPALSALYLMGSSGSIGQSTSSDLDIWVCYN 172

Query: 123 SWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILL 182
           S L+  +   LQ K   +  WA+   +EV FFL+D +RF   E  SL GE+CGSTQH+LL
Sbjct: 173 SELNDRDIDRLQTKAEQISVWASGFNLEVHFFLMDAHRFSGGEQQSLTGENCGSTQHVLL 232

Query: 183 LDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEE 242
           LDEFYRT   LAG    W +VP   E  Y   + T+   G +      D G +++L A E
Sbjct: 233 LDEFYRTVQVLAGNIPAWWLVPTAFESEYRSALDTMAYDGYVNDANTTDFGPIATLPAGE 292

Query: 243 YFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPY 302
           + GA +WQ+YK+IDSPYK+VLK +LLE Y+ EYP    LA   K  ++  ++    LDPY
Sbjct: 293 FIGAGMWQIYKAIDSPYKSVLKLILLEIYAREYPAIESLAHQYKSDIYRMKLSLDDLDPY 352

Query: 303 CMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDE 362
            M+  R+  YLT  ++  RL L+RRCFY KV   LS+      WRR ++  L+  WGW +
Sbjct: 353 VMLYRRIESYLTERDEMERLALLRRCFYFKVGLNLSKPTRTYNWRRELMDYLLDSWGWTK 412

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
           + +A LDN   W I++V      L++ +  SYR L  FA  ++ +   S +D+ +L+RKL
Sbjct: 413 STIAHLDNFRAWTIEEVLSERRLLINELTHSYRFLTEFASEHHSTHVMSQRDLLILSRKL 472

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSG-WYLYNRAPNIESIISHQP 481
           +AAF+  PGK+  +   +  DLS   +        +      W  YNR  + +   S  P
Sbjct: 473 HAAFDRRPGKIDFIRIGLDVDLSHEKIRLYERESKQEPGVFLWAAYNRPLDAD--PSPSP 530

Query: 482 LEYNRYLNKLVAWAWFNGLLTSRTRLYIKG-NGIVDLPKLQEMVADVSHHFPLRLPAPTP 540
           L+Y++ L + + W+  NGL+++   + I      +   +++ ++A +    P  LP    
Sbjct: 531 LKYSKGLLETLLWSHLNGLISAHLHIPIYPMQQAITEFEIRMLLASMRQILPTPLPKIDS 590

Query: 541 KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRN 600
            + Y P  +  +   +N+  DP      + +     + +   F   +  LV S+D++  N
Sbjct: 591 NSFYHPAILTKVVCFINVGRDPLHYLSARGLQKISARSNSLDFSALRENLVLSIDMVLVN 650

Query: 601 SWNEVRTLHFNGEQSMIEALKTILGKMH-QDAAPPDSVEVFCYSQHLRGLIRTRVQQLVS 659
           +W EV    F  + +M +ALK+++ +++ Q  +    +E  C++Q     I  RV+ L  
Sbjct: 651 TWGEVVVERFADQDAMTKALKSLINRVNKQTRSGLPIIETVCHNQTRPQAIAKRVKDLFE 710

Query: 660 ECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLS 719
           + +    S    +  RF    +S             + Q L +  E    + H +     
Sbjct: 711 DALSALCSPMHPKNTRF-VFNLSDNCILFQHINRVTNFQTLSDVTELEQHLGHEQAEYSP 769

Query: 720 VQVETNHVKLPAVVDGF---ASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSK 776
           V  +    +   ++       S   +   FE    +    +Y++DE   +  +     + 
Sbjct: 770 VVFDRVFQQDQPLMSQLYQTHSANTVNVAFELQTTQAT--LYLIDEQGSLMRFVQPLHNV 827

Query: 777 EELVRDVSRFYSSSHDRFTYGSS--FINFNLPQFYQIVKVDGREQVIPFRTKSIGN 830
             L+  + RF   +  R    +    +     Q +QIV+     ++   +   + N
Sbjct: 828 ATLLSPLLRFLKVTEHRQRSNTDVQLMPQRTIQCHQIVRQKNGLELKRIKLGGLVN 883


>UniRef50_Q1I310 Adenylate cyclase n=23 Tax=Pseudomonas RepID=Q1I310_PSEE4
          Length = 954

 Score =  821 bits (2121), Expect = 0.0,   Method: Composition-based stats.
 Identities = 284/842 (33%), Positives = 430/842 (51%), Gaps = 24/842 (2%)

Query: 3   LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGIC 62
             +  L+ R   INQ R+ RAL  +    QQV +LLP   H +HPL+PGY+ GN P G+ 
Sbjct: 18  KELSRLRARFLKINQGRLARALEGLSTRQQQVLTLLPLFFHVNHPLLPGYVSGNTPAGVS 77

Query: 63  LYTPDETQRHYLNELELYRGMSVQDPPKGEL-PITGVYTMGSTSSVGQSCSSDLDIWVCH 121
            + PD           L R  + +        PI G++ MGS  ++ Q+  SD+D+WVCH
Sbjct: 78  GFEPDTELL--AEAQRLTRSFTYKARHGNPPQPIHGLFLMGSLGTLAQAEQSDMDLWVCH 135

Query: 122 QSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGS-LGGEDCGSTQHI 180
              LD +    L+RKC LLE+WAA+ G E   FLI+   F   E  S L  +DCG+TQH 
Sbjct: 136 APGLDEQALAELRRKCQLLEDWAATQGAEAHLFLIEPQGFVQGERDSRLSSDDCGTTQHY 195

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLLDEFYRTA+ LAG+  LW +VP  +E +Y DY  TL ++  +   + LDLG L+ + A
Sbjct: 196 LLLDEFYRTALWLAGRTPLWWLVPVYQEHNYRDYTQTLLSKRFIRVTDALDLGHLAHIPA 255

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
            EY GA LWQLYK IDSPYK++LK LL E Y+ E+P+ R L+ D KQ +    +    LD
Sbjct: 256 GEYVGAGLWQLYKGIDSPYKSLLKLLLTETYASEHPHVRCLSLDFKQAVFANRLDLDELD 315

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS--RERACVGWRRAVLSQLVSEW 358
           PY M+  R+ +YL    +  RL+LVRR  YLKV +KL        VGW+R +L++L  EW
Sbjct: 316 PYVMVYRRIEQYLLRRGETARLELVRRSLYLKVNKKLGGLGRSRNVGWQRQLLARLAEEW 375

Query: 359 GWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
           GWDE +LA+LD+R+ WK+ QV     EL+  +  SYR L +FAR  N +  A  +D+ VL
Sbjct: 376 GWDERQLALLDSRSQWKVRQVAVERRELVAELNHSYRFLTQFAREQNANSRADQRDLNVL 435

Query: 419 TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRS-GWYLYNRAPNIESII 477
            R+LYAAFE   GK+ ++NP I+PDL+E  LT +  P  +   +  W LYN    +    
Sbjct: 436 GRRLYAAFERRAGKIEMINPGIAPDLAEDTLTLVQSPNRKEPGTHHWGLYNGNLGVHEWE 495

Query: 478 SHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIK-GNGIVDLPKLQEMVADVSHHFPLRLP 536
              P++  R L +L+ WA  NG++ S TRL +  G   +   +L  ++  +    PL L 
Sbjct: 496 HFSPIKRCRELLELLTWAHRNGVIDSSTRLALHPGASDLSEFELFNLIGSLQQSIPLPLE 555

Query: 537 APTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDL 596
             +   L  P     + ++VN+  DP    R+  +     + D  S+   +  LV ++D 
Sbjct: 556 TVSEVRLLQPSVADEILLLVNVGVDPLRHHRDLNILMTTERTDSLSYAGVRENLVLTLDQ 615

Query: 597 LYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQ 656
           +  NSWNEV    ++GE ++   L+  L  +   +  P  V V CY  +    I  RV++
Sbjct: 616 ITLNSWNEVLVQRYDGEHALARCLRDFLNSLGHRSHRP-RVRVCCYCHNRAQAISQRVEE 674

Query: 657 LVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLH 716
           +  + ++L L    Q       L+V+  T  L  +   V++  L         +   +  
Sbjct: 675 IF-DTVQLLLD---QNLNHRYLLQVARHTHVLELQPGQVTLATLVEHDALLATLGEERNS 730

Query: 717 GLSVQVETNHVK---LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCE 773
              + ++ N ++   LP V+     +  IQ F+     +   ++Y+LDE N +       
Sbjct: 731 YSPLHLDANALQDYDLPLVLSQGQPQ-CIQVFYRLL--DGWADLYVLDEYNALWQQRLPL 787

Query: 774 GSKEELVRDVSRFYSSSHDRFTYGSSFINFNL----PQFYQIVK-VDGREQVIPFRTKSI 828
             +  L+  + RF  S   R        +         +YQ++    G+ + +  R   +
Sbjct: 788 QDELHLLLPLQRFLQSMVMRRDAQLPLDSLQQASLDILYYQLLPSGVGKARGLEPRPAPV 847

Query: 829 GN 830
             
Sbjct: 848 DG 849


>UniRef50_Q088L2 Adenylate cyclase n=1 Tax=Shewanella frigidimarina NCIMB 400
           RepID=Q088L2_SHEFN
          Length = 819

 Score =  767 bits (1981), Expect = 0.0,   Method: Composition-based stats.
 Identities = 242/834 (29%), Positives = 409/834 (49%), Gaps = 54/834 (6%)

Query: 9   KQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDE 68
           K   + +N +R+ R L  +  +   ++ L+P L+H++   +PG +D + P GI  +T  +
Sbjct: 10  KDLAEKLNGIRLARVLNVLPESQLHLFHLIPFLIHHNQINVPGIIDPDTPCGIHGFTLSD 69

Query: 69  TQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSE 128
                 + L L     +Q     +    G+Y MGST+S GQ+  SD+DIW+ + S L  +
Sbjct: 70  AIVSACDALSLSIPEMIQ---PSDCVFEGIYAMGSTASFGQNPQSDVDIWLVYNSKLTDD 126

Query: 129 ERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRH----NESGSLGGEDCGSTQHILLLD 184
           + +L++ K  L+ +W A    EV+F+L+   +FR     +    +G E  GS+QH LLL+
Sbjct: 127 QLKLIEYKNKLISDWFAGFEFEVNFYLVHPMQFRECSAFDNCQPVGLEHSGSSQHWLLLE 186

Query: 185 EFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYF 244
           EFYR+ +RLAGK + W      +   +D  +              L LG ++SL A EYF
Sbjct: 187 EFYRSHIRLAGKVVAWWPDANSQNTEFDASL--------------LYLGDINSLPAAEYF 232

Query: 245 GASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCM 304
           GASLWQLYK ++ P+KA+LK LLLE Y+ EYP+  L+ + I Q     +  S   D Y +
Sbjct: 233 GASLWQLYKGLNKPHKALLKVLLLETYASEYPSTTLITQQIWQYCEQQDF-SVDNDAYLL 291

Query: 305 MLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS--RERACVGWRRAVLSQLVSEWGWDE 362
           + +R+  YL A  D  RL++VRRCFYLK    LS     +   WR   +  LV +W W  
Sbjct: 292 LYQRIETYLIAQGDDNRLEIVRRCFYLKSGVTLSCLSPNSAADWRVEKIQNLVKQWAWSH 351

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
             +A LDN   W   Q++  + +L + ++ SY+NL++FA +  LS     +++G+L RKL
Sbjct: 352 ELVATLDNSPYWHAGQLKWFNQQLSELLLVSYKNLLQFASKQTLSERMRVEELGLLARKL 411

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRA---PNIESIISH 479
           +  F      +  +N   S   +E +LT  +        S +YLY +A    +    + +
Sbjct: 412 HTYFSEDTHLLQPLNRLWSLSTAEKSLTIFHCRQA----SRFYLYRQAYLDKDPSQAVDN 467

Query: 480 QP--------LEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHF 531
            P        +     +  LVAW+  NGL T+ T+ +  G G     KL  +   +    
Sbjct: 468 DPAHEFDDHSIHEADNICNLVAWSVLNGLATADTQWFQVGRGKRRTDKLSYLTRKL---I 524

Query: 532 PLRLPAPT--PKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNC 589
           P+    PT   + L  P   + + +I N++ DPT     Q +  +    ++ SFG+ +  
Sbjct: 525 PIMHNVPTVYKRDLCEPWCYQKIVLITNMDRDPTTQLSEQELILEHVNANILSFGQTKIS 584

Query: 590 LVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGL 649
           +V SV ++  NSW E ++  FNG+ +++EA+  I+  + +     D   + C S  L+  
Sbjct: 585 MVSSVAIVCLNSWGEWQSHRFNGKTALLEAISFIILGLKRSNEQVDLSIISC-SAKLKQP 643

Query: 650 IRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGA 709
           I  +++ L+  C  L +    Q       + +  Q + + F  L +  +K+ + I   G 
Sbjct: 644 IFNQLKTLLLRCYGL-MKKVNQTNTLMHPITIGEQHYSMHFNSLGMMYRKV-DLITGTGN 701

Query: 710 ISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVY 769
            + + L    +  E  ++  P+V+  F   G  Q+F  E       +++I D++N++E  
Sbjct: 702 FNSSVLPYADL-AEDPYLNSPSVIQKFIVMGAKQYFLRERH--QTLDVFIADDNNQLEHL 758

Query: 770 HHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPF 823
            +   S  + V   S  Y     +         FN+PQF+Q+V ++G+  VIPF
Sbjct: 759 QYQHTSINDFVAKESHLYVFDEQKQR----SPVFNMPQFFQLVDIEGKLTVIPF 808


>UniRef50_A1SAP9 Adenylate cyclase n=18 Tax=Shewanella RepID=A1SAP9_SHEAM
          Length = 809

 Score =  764 bits (1974), Expect = 0.0,   Method: Composition-based stats.
 Identities = 265/818 (32%), Positives = 405/818 (49%), Gaps = 44/818 (5%)

Query: 13  DAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRH 72
           D +N++R+ RALA + P  + +   +P LLH+H P +PGY     P G+  + P E    
Sbjct: 16  DRLNKVRLARALALLSPLKRHLLHAIPLLLHFHGPRIPGYNGHATPCGLAGFEPQEPHLE 75

Query: 73  YLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQL 132
               L L       D P     I G+Y MGST S GQ+  SD+D+WV H+  L +++ Q 
Sbjct: 76  AARVLSLGLPSLRADWP---YAIEGIYAMGSTGSFGQNPFSDVDVWVIHEPNLSADDIQA 132

Query: 133 LQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGS------LGGEDCGSTQHILLLDEF 186
           L  K  LL  W A    EV+F+L+   +FR ++S S      LG E  GS QH LLL+EF
Sbjct: 133 LADKLVLLHQWFAGFEFEVNFYLVHPFQFRADKSYSGNGRVRLGVEHSGSAQHWLLLEEF 192

Query: 187 YRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGA 246
           YRT + L GK + W                          ++ L LG + SL A EYF A
Sbjct: 193 YRTQICLGGKPLYWWPDA-------------------RPSSDGLWLGDVQSLPASEYFSA 233

Query: 247 SLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMML 306
           SLWQLYK +  P+KA+LK LLLEAY+W YPN   L+  +      G+  S   DPY ++ 
Sbjct: 234 SLWQLYKGLVKPHKALLKVLLLEAYAWRYPNTEQLSTRVWLHTTKGDF-STANDPYFLLY 292

Query: 307 ERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLA 366
           E + EYL AIED  RL++VRRCFYLK   +LS  +    WR   +  LVS W W +A + 
Sbjct: 293 EAIEEYLLAIEDHRRLEIVRRCFYLKCAVRLSHPQQPKDWRYLKMQLLVSAWEWPDALIQ 352

Query: 367 MLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAF 426
            LD+  +W   Q++  + +L + M+ SY+ L+RFA  + ++     +D+G+LTRKL+  F
Sbjct: 353 TLDDCEDWHTGQLQWFNAQLNELMLVSYQKLLRFAANHGVNEGLRVEDLGMLTRKLHTCF 412

Query: 427 EALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNR 486
                 V+ +NP  S  L EP LT I       +    YLY + P   ++     +    
Sbjct: 413 NEDKHLVSKLNPLWSSRLQEPVLTVITSQSDGTH----YLYRQEPQASALKGEAAVYVAD 468

Query: 487 YLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSP 546
            L  L+ WA  N +   +T+ +  G   +   +L      +           + + L  P
Sbjct: 469 NLASLLLWACINQVCDDQTQWFSYGERRLG-ARLAATDKRLREAIKDTELKVSKQDLCQP 527

Query: 547 CEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVR 606
              R L ++VNLE+DPT  +  Q V  D    ++FS G  Q  ++GS+D+L  NSW E  
Sbjct: 528 WHYRKLVLVVNLEHDPTPDWPGQEVLVDIMNANLFSLGRKQLNMLGSLDVLSFNSWGEWH 587

Query: 607 TLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRL 666
             HF GEQ++++A+  +   + + A   D   + C S  L   +   V  L+ +  +L  
Sbjct: 588 AHHFEGEQALLKAMTFLAPGIRRAAGRLDLRTLGC-SARLTFQLELAVHSLLKQVAKLSC 646

Query: 667 SSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQ--VET 724
            +    +   + LR+  + +GLFF  L V+ + L +A   Y  +S   L  +      + 
Sbjct: 647 QA-SASSTLVQPLRIGNRNYGLFFNTLGVAYEDLADAPSIYKQMSRGHLLSIPRPELGDD 705

Query: 725 NHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVS 784
               +P ++  +A+E +IQ+F      E G +++IL+  N +  Y     + E LV  VS
Sbjct: 706 PFASVPELIQDYATEDVIQYFLRPR--EEGIDVFILNHKNEISHYVQHGTTVEALVSKVS 763

Query: 785 RFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIP 822
           + ++       +G     FNLPQF+Q+V++ G  +  P
Sbjct: 764 QQHAFEGLYEMHG----RFNLPQFFQLVRMQGELKAQP 797


>UniRef50_B3PH57 Adenylate cyclase, class I n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PH57_CELJU
          Length = 651

 Score =  694 bits (1792), Expect = 0.0,   Method: Composition-based stats.
 Identities = 229/630 (36%), Positives = 331/630 (52%), Gaps = 19/630 (3%)

Query: 3   LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGIC 62
             +  L++R  ++N+ RV R L  +    QQ   LLP L H +HP++PGY+ G  P G+ 
Sbjct: 18  KQLTLLRRRFLSLNEQRVARTLTNLSERQQQFMQLLPLLFHVNHPMLPGYISGATPAGVY 77

Query: 63  LYTPDETQRHYLNELELYRGMSV-QDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCH 121
            Y PD+          L R  +  +D  +    I  ++ MGS  S+  +  SD+DIWVCH
Sbjct: 78  AYQPDKDSLRLAR--ILARSFTYTRDLVETTPGIDALFLMGSVGSIAHTAGSDMDIWVCH 135

Query: 122 QSWLDSEERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
              LD    Q L+RKC ++ +WAAS + +EV FFL+    F+  +  S+  E  GS QH 
Sbjct: 136 NPTLDLPALQELERKCQVITHWAASQIHLEVHFFLMTGEHFQTGKCSSMSSEASGSAQHY 195

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLLDEFYRTA+ LAGK  LW  VP   E  Y  Y  TL  +  +   E +D GGL  + A
Sbjct: 196 LLLDEFYRTALWLAGKVPLWWFVPVTREADYRRYSETLLHKRFIKAAEVIDFGGLPFIPA 255

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYS----WEYPNPRLLAKDIKQRLHDGEIVS 296
            E+ GA +WQLYK+I SPYK+VLK LLLE Y+     +      LA  +K+ L++ E   
Sbjct: 256 NEFIGAGIWQLYKAIASPYKSVLKLLLLEVYASGDTAQDTATEPLALSLKRALYEREPDV 315

Query: 297 FGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERAC--VGWRRAVLSQL 354
             LDPY M+ ER+  YL A     RL+LVRRC Y K+ + LSR+ A     W+R +L  L
Sbjct: 316 DRLDPYVMIYERIERYLCARHQDARLELVRRCLYFKINKPLSRKNARTKKSWQRVLLEDL 375

Query: 355 VSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQD 414
              WGW+  +L MLDNRA WK   V      L++ +  SYR L    ++  L+ + S  +
Sbjct: 376 THAWGWNSHQLHMLDNRAYWKSPHVIAERALLVNELNHSYRLLAELNKQLGLNAAISTDE 435

Query: 415 IGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIE 474
           + VL RKL+AAFE   GKV  +NP IS +LSEP L F  V         W L   +    
Sbjct: 436 LQVLGRKLHAAFERKAGKVEYINPGISRNLSEPALCF--VQDKSVAGESWQLVRGSQQDL 493

Query: 475 SI--ISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI--KGNGIVDLPKLQEMVADVSHH 530
           ++  ++ +P+   R L +L+ W+  NGLL   TR+ +  K   I  L K Q+++  +   
Sbjct: 494 TLRSVAVEPVRRARSLVELLVWSQVNGLLVPGTRVDLISKDYQITALQK-QQLLQAILQW 552

Query: 531 FPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCL 590
            P     P  +A  S   +  + ++ NL  +P A    + +     + D   F   +  L
Sbjct: 553 LPEPH-QPEHQAFTSAARVEKVLMLFNLGVEPQAELHKRGMQMLSAQSDPLGFSGFRANL 611

Query: 591 VGSVDLLYRNSWNEVRTLHFNGEQSMIEAL 620
           V SVD++  NSW E+   H+  + +++ AL
Sbjct: 612 VLSVDIVQLNSWGELVARHY-PQDALVNAL 640


>UniRef50_C8R2N0 Putative adenylate cyclase n=1 Tax=Desulfurivibrio alkaliphilus
           AHT2 RepID=C8R2N0_9DELT
          Length = 658

 Score =  580 bits (1494), Expect = e-163,   Method: Composition-based stats.
 Identities = 176/658 (26%), Positives = 305/658 (46%), Gaps = 49/658 (7%)

Query: 10  QRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL-DGNVPKGICLYTPDE 68
            R    N+ R+ +++         +++ +P LLH +HP +PGYL +   P GIC Y P  
Sbjct: 8   ARYHLYNEERIAKSVLLNPHKSNIIFAAVPYLLHVNHPDLPGYLNEPAAPCGICNYNPAT 67

Query: 69  TQRHYLNELELYRGMSVQDPPKGE--------LPITGVYTMGSTSSVGQSCSSDLDIWV- 119
                L     +R    Q  P+GE          I  + T+GS  ++ QS  SD D WV 
Sbjct: 68  AFSFEL----FHRFFPGQSVPRGEEKMLPGNLCAIRSLMTIGSVGTIAQSEKSDCDYWVS 123

Query: 120 CHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDC-GSTQ 178
            H+S L +   +LL  KC+ +  W A  GVE  FFL+D  + R N   S   E+  G++ 
Sbjct: 124 VHRSQLGARGMELLAEKCAAIAAWTAKKGVETHFFLMDIEQTRENSFESAAMEESAGTSL 183

Query: 179 HILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWLDLGGLSS 237
            ILL DE +RT V +AGK +LW  +P   EE+HY   V  L  +  + P++++DLG +++
Sbjct: 184 KILLKDELFRTHVLVAGKPLLWWFLPPGLEEKHYHGLVKRLVREHKINPDDYVDLGCVAT 243

Query: 238 LSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYS-WEYPNPRLLAKDIKQRL------- 289
           +  EE FGA LWQ+ K++DSP+K+V+K   LE     +  +P L +  IK+ +       
Sbjct: 244 IPREEIFGACLWQMNKALDSPFKSVIKFAYLELLLQDQQSSPALFSDKIKRLVTYPEKLP 303

Query: 290 -HDGEIVSFGLDPYCMMLERVTEYL-TAIEDFTR--LDLVRRCFYLKVCEKL-SRERACV 344
                +    +DPY ++   +  +   A     R   DL+R C +LK  E + S++ A +
Sbjct: 304 DQMEMLDPGEIDPYLLLAREIIAFYQQANNRPIRQWADLIRECLFLKTLEMVESQKHAKM 363

Query: 345 GWR---RAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFA 401
           G +   +A++ Q+  +W    A      N   W+   +    + +   + ++Y+ L R  
Sbjct: 364 GQKSHHKAIMEQM-EDWDILPANRQHFLNFRYWQYRDLLAFGSRVHGYLAETYKRLRRVF 422

Query: 402 RRNNLSVS--ASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRA 459
           +  +  V    S +DI  L RKL+  +E  P K+  +       ++  ++T I++     
Sbjct: 423 KEIDPEVGLTISERDIATLGRKLFTFYEKKPNKIDYIRSVSRYHMTMEDIT-IHITK-YQ 480

Query: 460 NRSGWYLYNRAPNIESIISH--QPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNG-IVD 516
            R  +Y +    +  +I       +  + +L +LV W   NG+L   T+L++  N   +D
Sbjct: 481 ERFFYYAFQGNLDHNTIREQVGAAIRRDDHLVRLVTWLMVNGMLARHTKLHLTKNFLPID 540

Query: 517 LPKLQEMVADVSHHFPL-RLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFR-------N 568
           L  +Q +   +   FP+       P+ L     I    ++VN   +P    +       +
Sbjct: 541 LADIQILAEKMLDTFPMVDFSKIPPQHLVEQENILRALVVVNFFKEPVKGNKTLASTIIS 600

Query: 569 QVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGK 626
           +  + ++   D  +  + +N L+  +   Y + WN    + F   Q  I A+K +L K
Sbjct: 601 ENSYGEYFLHDYNTLAQLKNALLTLLTRHYVSRWNN-NLIVFIPNQDEISAIKNLLEK 657


>UniRef50_B4RT26 Adenylate cyclase, class I n=2 Tax=Alteromonas macleodii
           RepID=B4RT26_ALTMD
          Length = 661

 Score =  579 bits (1493), Expect = e-163,   Method: Composition-based stats.
 Identities = 169/680 (24%), Positives = 292/680 (42%), Gaps = 63/680 (9%)

Query: 11  RLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDG-----NVPKGICLYT 65
           R+   N+ R++RAL  M    + ++ +LP L+H +H  +PG++       +VP GI  Y+
Sbjct: 19  RVLRYNKARIERALTLMPEKHRPLFHVLPFLVHVNHESLPGFVAPLSTGESVPFGISNYS 78

Query: 66  -----PDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
                     R + +E  L+  +  Q  P+ +  +  +  MGS  ++ Q+  SD D WVC
Sbjct: 79  FRTDIEKALLRCFPSESHLFADIK-QIWPR-QRAVDALVLMGSVGTIAQTDDSDFDFWVC 136

Query: 121 -HQSWLDSEERQLLQRKCSLLENWA-ASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQ 178
                  S    LLQ+K + +E WA  + G+EV FFL + ++ + N+ G   GE  GS Q
Sbjct: 137 IDGKQFTSTALSLLQQKLTAIEKWADQTFGIEVHFFLSEIDKVKQNDFGVAEGESAGSAQ 196

Query: 179 HILLLDEFYRTAVRLAGKRILWNMVP-CDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSS 237
            + L  EFY T + +AGK   W + P    E+ Y     +L   G    + ++DLG L  
Sbjct: 197 ALFLKAEFYNTNIVVAGKAPFWWLTPEKTSEKQYQAIYNSLEKGGSPDLDWFMDLGHLEK 256

Query: 238 LSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVS- 296
           L A E FGA++WQL K++DSP+K+VLK   LE Y       + L   +K+ +H G     
Sbjct: 257 LDASELFGAAIWQLGKAMDSPFKSVLKMAKLEVYLANIAEGQPLCNLLKKHVHRGAEAPG 316

Query: 297 --FGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRE---RACVGWRRAVL 351
               +DPY +M + +  + +       + ++R C YLK    LS+         ++R ++
Sbjct: 317 HVADIDPYSLMFDELITHYSEHGQAEDIAVLRECLYLKCGCALSQPLMEDEKPNFKRRIM 376

Query: 352 SQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSAS 411
           +    +WGW+  +L+  DN+  W   +  +    +   +++ YR + +    +   +   
Sbjct: 377 ASYARQWGWNRKQLSHFDNQQEWNFSERVQLSRRIHRFLLKCYRRISKELSHHQQVMD-- 434

Query: 412 PQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNR-- 469
            +D+ VL R+L   +     K+  +       L    +T I +   +     W  Y    
Sbjct: 435 EKDMTVLGRRLSTYYAKKADKIEFLRRAFDESLYCEKVT-IAMRQLKNGEEVWSAYAGDL 493

Query: 470 APNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGN-GIVDLPKLQEMVADVS 528
                 I   Q +        L+ W   + ++ + +++Y+  N G V    L +++  + 
Sbjct: 494 LSKSGIIDESQKITQASSAIALMVWCVSSKIIDTHSKVYLDYNYGEVSELDLNDLLKHLC 553

Query: 529 HHF-PLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQ 587
            +F P+++ A     L +P  I     IVN    PT                       Q
Sbjct: 554 KYFPPVKVSALPRNNLLAPERITACFAIVNF---PTL---------------------RQ 589

Query: 588 NCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLR 647
              V  V ++Y  SW E         +S  E L T+   + + +  P      CY    R
Sbjct: 590 KATVEDVSVIYSTSWGETFL------KSGSEVLDTLWYDLQEVSPAPP-----CYVMVPR 638

Query: 648 GLIRTRVQQLVSECIELRLS 667
           G  + R+     E  EL  +
Sbjct: 639 GNQQARILGEFLEAHELNFT 658


>UniRef50_Q1NP63 Adenylate cyclase n=2 Tax=delta proteobacterium MLMS-1
           RepID=Q1NP63_9DELT
          Length = 656

 Score =  554 bits (1427), Expect = e-156,   Method: Composition-based stats.
 Identities = 168/663 (25%), Positives = 301/663 (45%), Gaps = 46/663 (6%)

Query: 3   LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL-DGNVPKGI 61
           + ++    R    N  R+ +++         +++ +P LL  ++  +PGY+ D   P+GI
Sbjct: 1   MSLKEKSNRYHRYNAERIAKSMMLNANKSNLIFAAVPYLLQVNNQDLPGYVADPACPRGI 60

Query: 62  CLYTP-----DETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLD 116
           C + P     D  +R +       R   V   P+    I  + T+GS  ++ QS  SD D
Sbjct: 61  CDFDPTTLSGDLFRRFFPTAQATAREEMV--LPRSSCAILSLKTIGSIGTIAQSEKSDCD 118

Query: 117 IWV-CHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGG-EDC 174
            WV   Q  LD +  +LLQ+KC+ +E WA   GVEV FFL+D  + R N   S    E  
Sbjct: 119 YWVSVDQQQLDGQGLELLQQKCTAIEEWADKRGVEVHFFLMDITQTRENSFDSAAEDESA 178

Query: 175 GSTQHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWLDLG 233
           GS   ILL DE +RT V +AGK +LW  +P    E  Y   V  L  +  + P++++DLG
Sbjct: 179 GSALKILLKDELFRTHVLVAGKPLLWWFIPPGLNEGQYKALVARLIKERKIDPDDYVDLG 238

Query: 234 GLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLL-LEAYSWEYPNPRLLAKDIKQRL--- 289
            ++ +   E FGA LWQ+ K++DSP+K+V+K          +     L +  +K+ +   
Sbjct: 239 YVAGIPKAEIFGACLWQMNKALDSPFKSVIKFAYLELLLQQQQNALPLFSDKVKRLVTYP 298

Query: 290 -----HDGEIVSFGLDPYCMMLERVTEYLTA--IEDFTRLD-LVRRCFYLKVCEKL-SRE 340
                    +V   +DPY ++   +  +     +E   +   L+R C +LK  E + S++
Sbjct: 299 EKLEDRMEALVPEEVDPYLLLAREIIAFYQQAKLEQMRKWSALIRECLFLKTLEGVESQK 358

Query: 341 RACVGWRRAVLSQLVSEWGWD--EARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNL- 397
           +A +G +  + + +     WD   A      +   W+  ++    N + + ++++Y+ L 
Sbjct: 359 QAKMGEKSHLKALMTQMETWDILPAEHQRFLDFRYWQYKELLALGNRIHEYLIETYKRLR 418

Query: 398 ---IRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYV 454
               +F     L+   + +DI +L RKL+  +E    KV  +       ++  ++T I+V
Sbjct: 419 WIFTKFGPDTGLT--ITERDISILGRKLFTFYEKKDNKVEYIRSISRQSMAMEDIT-IHV 475

Query: 455 PPGRANRSGWYLYNRAPNIESIISH--QPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGN 512
                +R  +Y +    + E++ +     +  +  L +L+AW   NG+L S TRL++  N
Sbjct: 476 TK-YDDRFFYYAFQGEQDHETVKTRVEAVIRRDDKLIRLLAWLLVNGMLASHTRLHLTKN 534

Query: 513 G-IVDLPKLQEMVADVSHHFP-LRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFR--- 567
              +DL  +Q +   +   FP +   A +P+ L     I    ++VN    P    +   
Sbjct: 535 FLPIDLVDIQGLAESMLATFPVVHFSAISPQQLLEQENILRALVVVNFFKQPVKGSKTLP 594

Query: 568 ----NQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTI 623
                +  + ++   D  +  + +N L   +   Y + WN      F   Q     +K +
Sbjct: 595 STIITENSYGEYFTHDYQTLTQLKNALRALLTRHYVSRWNNNLEF-FIPHQDEANTIKQM 653

Query: 624 LGK 626
           LGK
Sbjct: 654 LGK 656


>UniRef50_C0N363 Putative uncharacterized protein n=1 Tax=Methylophaga thiooxidans
           DMS010 RepID=C0N363_9GAMM
          Length = 827

 Score =  527 bits (1357), Expect = e-148,   Method: Composition-based stats.
 Identities = 169/826 (20%), Positives = 326/826 (39%), Gaps = 103/826 (12%)

Query: 48  LMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSV 107
           ++PG+++ +VP G+  Y PD+T      ELE       +       P+ G+Y +     +
Sbjct: 1   MLPGFINDDVPAGLIDYQPDKTTLDKAKELET--SFKYRRKALRRYPLRGLYLIHPQGVL 58

Query: 108 GQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESG 167
             + +  L +W+ H + ++ E+RQ L  K   + +W  + G+ V + L+ E     N   
Sbjct: 59  NATDNGPLQLWLLHSNNVNDEQRQGLTLKLDAVVDWMQAAGLTVEYKLLAEADLHTN--- 115

Query: 168 SLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPN 227
           SL G +         +D  Y + + LAG    W +    E++ Y   +  +  Q +L   
Sbjct: 116 SLQGWE---------IDLLYHSGMVLAGSVPYWWLSTTAEDQDYQHTINEIKNQRMLNQV 166

Query: 228 EWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRL--LAKDI 285
            ++D G  +   AE  F       Y++I +   +    L LE    +     L  L+  +
Sbjct: 167 SFVDFGAAAPSHAERIFTLC----YQAIKNSLHSGNDWLELEYLHTQLEQDELPCLSHLL 222

Query: 286 KQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSR--ERAC 343
           KQ++H  ++ S   D   + L ++ ++  A          R   YL   E LS+  ++A 
Sbjct: 223 KQQVHQQKL-SLSHDISHLKLLQIAQHNPASH-------AREALYLVSSELLSKSVKQAR 274

Query: 344 VGWRRAVLSQLVSEWGWDEARLAMLDNRANW----KIDQVREAHNELLDAMMQSYRNLIR 399
             WRRA +  LV +W W E +L  LD R         + + E+ + LL  M         
Sbjct: 275 YPWRRAFIQSLVEQWNWSEEKLQQLDQRDYAANKRCFELIGESCHRLLKQMTD------- 327

Query: 400 FARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRA 459
           FAR + L V +    +  L +     F+     +  +  Q+ P  S  +  F++      
Sbjct: 328 FAREHALEVDSQ---LAELKKCYQLRFKPAADVIDCLPKQMRP-ASNSDRLFLH---RFQ 380

Query: 460 NRSGWYL---YNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVD 516
           N S W++     + P   ++  H+       L  ++AWA  N +L+    L +       
Sbjct: 381 NHSDWFISFQLLQKPTDSALFRHE------SLLHVLAWAVSNQILSRSNWLSVNDQ---- 430

Query: 517 LPKLQ-EMVADVSHHFPLRLPAPT-----PKALYSPCEIRHLAIIVNLEYDPTAAFRNQV 570
           L K+    V ++S H   R  A +       A   P  I+ + +I NLE   + +   Q 
Sbjct: 431 LQKVSTNTVVELSQHVFRRHLADSDLFTHSNAATQPESIQQIMLISNLERQASDSLSQQG 490

Query: 571 VHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQD 630
           +    ++ D F++  ++  LV SVD L  ++  +  +   N + + +E L  +L      
Sbjct: 491 LQLSSKQNDPFNYTSSRQSLVLSVDGLLLSNTGQWHSFALNDDHAPLELLIYLLN-WQPS 549

Query: 631 AAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFF 690
           +   +++  +C +      I  R+  L ++    R      + GR   L  +G+ + L +
Sbjct: 550 SLTQENISGWCPTPIFGQSITQRLNSLTAQL--CRHYQQFPQHGRL-LLNYAGRAYSLQW 606

Query: 691 ERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFA-SEGIIQFFFEET 749
           +       +   + + + A++ N+           HV  P+ +D +  S+G+  +  ++ 
Sbjct: 607 QDNQADYTRRPASQDLWQALAENR-----------HVFTPSALDNYLDSDGLFNYLLQK- 654

Query: 750 QDENGFNIYILDESNRVEVY-----------HHCEGSKEELVRDVSRFYSSSHDRFTYGS 798
           Q  N  +++I  E N +  Y                ++  LV  + +F S   +      
Sbjct: 655 QASNSISVFIYLEQNTIICYLIDELGNLIRQQFQHLTESTLVAHLHKFLSEIKNTRQIDQ 714

Query: 799 SFINFNLPQFYQIVKVDGREQVIPFR-TKSIGNMPPANQDHDTPLL 843
                   +FY++ +     Q +            P      +P L
Sbjct: 715 -------LRFYRLRREKQGWQRVALATPAQTRGYLPITVTMTSPAL 753


>UniRef50_C0QEU2 CyaA2 n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QEU2_DESAH
          Length = 1302

 Score =  522 bits (1344), Expect = e-146,   Method: Composition-based stats.
 Identities = 163/643 (25%), Positives = 288/643 (44%), Gaps = 67/643 (10%)

Query: 9    KQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDG--NVPKGICLYTP 66
            ++     N+L +  A+    P    ++ ++P L+H +    PGY       P+GI  Y P
Sbjct: 683  EKLFLNQNRLSILTAMDVFKPKQADLFEIIPLLIHENIDF-PGYQADLEQSPRGIAEYRP 741

Query: 67   ----DETQRHYLNELELYRGMSVQDPPKGELP-ITGVYTMGSTSSVGQSCSSDLDIWVCH 121
                 +T   Y+N  +L    S       ELP + G++TMGST ++ Q+  SD+D WVC 
Sbjct: 742  CKQTVKTASRYVNTGKLECRFS-------ELPHVEGLFTMGSTGTIAQAPDSDIDYWVCV 794

Query: 122  QSWLDSE--ERQLLQRKCSLLENWA-ASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQ 178
            +   D E  E +  Q+K +LLE WA      E+ FF++D +R R ++ G    E  GS Q
Sbjct: 795  R-GYDPECMEEKRFQQKLTLLEQWALGKFKTEIHFFIVDIDRARIDDFGDSTRESSGSAQ 853

Query: 179  HILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSL 238
             ++L +EFYRT + +AGK   W  +P      Y   +++           ++D G +  +
Sbjct: 854  GMILKEEFYRTMIHVAGKLPFWCTLPVSVSREYYGLLLSRICANRF-QCRFIDFGDIHEI 912

Query: 239  SAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHD-GEIVSF 297
             +  YFGAS+WQL+K ++SP+K+V+K  LLE + +     +LL    K +  D G  +  
Sbjct: 913  PSAAYFGASIWQLFKLLESPFKSVIKMALLEEFLYARGKKQLLCNRFKAQWMDPGLYLPL 972

Query: 298  G-LDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC--EKLSRERACVGWRRAVLSQL 354
            G +DPY ++L+ + +Y   + +     LV++CF+LK    +    +      R   +++ 
Sbjct: 973  GKIDPYYILLKSLVDYYGQVNNPAAERLVQQCFFLKTGITKDSDLDETLFSMRSFFITRA 1032

Query: 355  VSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQD 414
            + EW W    +    N   W+   +     ++   M+++Y  + +   R   ++  +P+D
Sbjct: 1033 MDEWAWTRKMVFENGNFRQWQYLSITRLSRQIQQYMVKTYIRINQAIDREQCAM-ITPED 1091

Query: 415  IGVLTRKLYAAFEALPGKV--TLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPN 472
              VL RK++  F + PGK+  TL+  +     +   LT++         S W L NR   
Sbjct: 1092 RTVLGRKMFVEFSSQPGKIPKTLMVSRSDRHFTSLVLTYL---SQTGKPSQWALVNRFSR 1148

Query: 473  IESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIV----DLPKLQEMVADVS 528
                 S + +     + ++ AW   N L +  T + +  N       D+  L + +    
Sbjct: 1149 SAP-ESREVIRQAETIEEIAAWFIQNQLFSPSTIINLLPNPTPVSSNDIQGLFQALYRFF 1207

Query: 529  HHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQN 588
            +H   +  +P  K L S   I  + I +NL        + + +H                
Sbjct: 1208 NHDNGK--SPGSKNLLSKARITAIFISINL----CVPRKKRRIHDSSA------------ 1249

Query: 589  CLVGSVDLLYRNSWNEVRTLHFNGEQS------MIEALKTILG 625
                    +Y NSW E+  +  + +Q       ++E LKT+L 
Sbjct: 1250 --------IYLNSWGEMFCIRISSQQGFVLRDEILERLKTMLE 1284


>UniRef50_C6BYH9 Putative adenylate cyclase n=1 Tax=Desulfovibrio salexigens DSM 2638
            RepID=C6BYH9_DESAD
          Length = 1306

 Score =  518 bits (1334), Expect = e-145,   Method: Composition-based stats.
 Identities = 153/633 (24%), Positives = 259/633 (40%), Gaps = 52/633 (8%)

Query: 5    IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNV-PKGICL 63
            IE         N  R+D A + +    +++  ++P LLH +   +   LD       +C 
Sbjct: 681  IEHCHACFAENNSRRLDWAQSKLDSKSRKLLKIIPALLHTNVFEIKSGLDPQTMSSRVCN 740

Query: 64   YTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQ- 122
            Y         L+E   +  +  +   +   PI    ++GST ++ Q+  SDLD WVC   
Sbjct: 741  YALSPQVIKLLDEF--FPDIKYEISKESSTPIEAFMSIGSTGTIAQTPDSDLDCWVCCNF 798

Query: 123  SWLDSEERQLLQRKCSLLENWAA-SLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHIL 181
            +   +E RQ L  K   +E WA    G+E+ FF++D    R N  G    E  GS Q  +
Sbjct: 799  TGRSAESRQNLGVKLQAIEKWAMNEFGLEIHFFIMDTREIRDNLFGLSDEESSGSAQSAI 858

Query: 182  LLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLT-PNEWLDLGGLSSLSA 240
            L +EFYRTAV LAGK  LW   P +  E    Y  T     +L   N  +DLG + ++  
Sbjct: 859  LKEEFYRTAVLLAGKPPLWWFTPPEAAE--KAYADTKKKVALLKGKNFCVDLGNIPNIPV 916

Query: 241  EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
            EE+FGASLWQ+ K I SP+K+++K  LLE Y+ +     LL + +K+ +  G+     +D
Sbjct: 917  EEFFGASLWQIVKGIKSPFKSIMKFGLLELYTSD-SKYSLLCEKLKKNIISGKRRIRRVD 975

Query: 301  PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVS-EWG 359
            PY  + + +  +  A E    + L      LK    +S +       RA   +L+     
Sbjct: 976  PYMRLYQDLANFYRANEKDEYIWLTAMALRLKCG-LVSEKEILSTPSRAEEIELIDFTMK 1034

Query: 360  WDEARLAMLDNRANWK-IDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
                     +N  +      V E    +   M+ +Y   +R  +     VS +P+D+  L
Sbjct: 1035 LSGEETGAFENFKDLSDFGSVAELGRRVNQFMVNTYMK-VRGEQDKFPGVSITPEDLTRL 1093

Query: 419  TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSG--WYLYNRAPN---I 473
             R +++AF     K+  +       L  P   F           G  W ++   P+    
Sbjct: 1094 GRIIFSAFAKRTNKILRL------SLPGPRTHFFNSINISRTEDGKIWNIHGEYPDESGA 1147

Query: 474  ESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIK-GNGIVDLPKLQEMVADVSHHFP 532
             +I++   +E    LN ++ W   NGL     ++     +G +   +++++ +++   FP
Sbjct: 1148 RNILTR--IESGPDLNFMLVWLALNGLYNQEMQIKTDISSGPLREREIKKLFSELMRFFP 1205

Query: 533  LRLPAPTP-KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLV 591
             +     P +   +   +     IVNL   P +    +                      
Sbjct: 1206 PKKTFNVPIEETLNTERLTKGFFIVNLCVPPESKKVQE---------------------- 1243

Query: 592  GSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL 624
              V L+Y  +W EV          ++E  +  L
Sbjct: 1244 --VHLVYSTNWGEVFCKPLKINMKLVETPEQYL 1274


>UniRef50_C0ARX7 Putative uncharacterized protein n=1 Tax=Proteus penneri ATCC 35198
           RepID=C0ARX7_9ENTR
          Length = 363

 Score =  514 bits (1323), Expect = e-144,   Method: Composition-based stats.
 Identities = 249/345 (72%), Positives = 289/345 (83%), Gaps = 1/345 (0%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           +YLYIETLKQRLDAINQLR++RA A+M   F+QVY L+P LLHYHHP +PGY+ GNVP G
Sbjct: 19  LYLYIETLKQRLDAINQLRLERAFASMCDVFKQVYGLIPVLLHYHHPELPGYIQGNVPHG 78

Query: 61  ICLYTPDETQRHYLNEL-ELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWV 119
            C + PD+ QR + N+L        ++    GELPITG+Y+MGSTSS+GQS  SD+DIWV
Sbjct: 79  TCFFEPDDMQRQWANKLINALCDEPMEGYASGELPITGIYSMGSTSSIGQSHCSDIDIWV 138

Query: 120 CHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQH 179
           CHQSWLD +ER LLQRKC L+E WA  LG++V+FFLIDENRFRH+ SGSLGGEDCGSTQH
Sbjct: 139 CHQSWLDQDERALLQRKCQLIEQWAGELGIDVTFFLIDENRFRHHASGSLGGEDCGSTQH 198

Query: 180 ILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLS 239
           ILLLDEFYRTAVRLAGKR+LW MVP +EE HYD+YV +LYAQGVLTPNEWLDLGGL  LS
Sbjct: 199 ILLLDEFYRTAVRLAGKRLLWTMVPVEEEHHYDEYVNSLYAQGVLTPNEWLDLGGLGELS 258

Query: 240 AEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGL 299
           AEEYFGASLWQLYKS+DSPYKAVLK++LLEAYS +YPN +LLA ++KQ LH GEIV++GL
Sbjct: 259 AEEYFGASLWQLYKSVDSPYKAVLKSILLEAYSADYPNGKLLALEMKQHLHRGEIVNYGL 318

Query: 300 DPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACV 344
           D YCMMLERVT YL +I D TRLDL+RRCFYLKVCEKLS E+   
Sbjct: 319 DAYCMMLERVTRYLVSINDLTRLDLIRRCFYLKVCEKLSNEKNTK 363


>UniRef50_C4XU05 Putative uncharacterized protein n=1 Tax=Desulfovibrio magneticus
           RS-1 RepID=C4XU05_DESMR
          Length = 608

 Score =  511 bits (1317), Expect = e-143,   Method: Composition-based stats.
 Identities = 148/638 (23%), Positives = 251/638 (39%), Gaps = 54/638 (8%)

Query: 37  LLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPIT 96
           +LP L+          L       I    P+             R       P   + I 
Sbjct: 1   MLPALVQAPLVRDDNGLRPAPAARIAGQVPNLATARLTAAHFGDRATEAATLPDDAIRIE 60

Query: 97  GVYTMGSTSSVGQSCSSDLDIWVC-HQSWLDSEERQLLQRKCSLLENWAA-SLGVEVSFF 154
            VYT+GS  +V Q+  SDLD+WV   ++     +    Q K   +   A     +E+ FF
Sbjct: 61  AVYTIGSVGTVAQTDDSDLDVWVVLAEADATRPDLPAFQDKLDAVSRQADRDHNLEIHFF 120

Query: 155 LIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDD 213
           L+  +  R N  G    E  GS Q  LL +EFYRTA+ +AGK+  W  +P D  EE Y  
Sbjct: 121 LMSVSDIRDNIFGYSADEGYGSAQGCLLKEEFYRTALVVAGKKPAWWCLPPDIAEEGYAK 180

Query: 214 YVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSW 273
            +  L         + LD G + +++ +EYFGASLW + KS+ SP+K+++K  LLE Y+ 
Sbjct: 181 AMAALGRTAADVAADCLDFGCVRAIAGDEYFGASLWMIVKSLTSPFKSIIKFGLLEKYAA 240

Query: 274 EYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKV 333
               P LL + +K  +   +   +  DPY ++ + V+ +         ++L+R+ F  K 
Sbjct: 241 HPGRPSLLCETLKASILANQGGLWRCDPYALLFKEVSRHYEESGQAGAMELLRQAFLQKT 300

Query: 334 ----CEKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLD- 388
               C++ +          A+L                L  +A  + +        L D 
Sbjct: 301 GFDPCDEYASRTG-----EAILDHFFPYAPPATGSCPPLPKKAGAEAETGFAQGMVLCDA 355

Query: 389 ---AMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLS 445
                +++Y  L   +     +   + +D  +L+R++ A+F    GKV  + P + P   
Sbjct: 356 ISNYFLKAYERLKNRSAELGAAGGLTERDQAMLSRRIAASFAKRVGKVMRL-PFLRPGRH 414

Query: 446 EPNLTFIYVPPGRANRSGWYLYNRAPNIESIIS----HQPLEYNRYLNKLVAWAWFNGLL 501
             +   I +  G+   +G  +    P +          + L     + +L AW   N L 
Sbjct: 415 LFDSLEIGLEDGKGREAGL-VVRGEPAVRGGARKSRQKETLRQELSVVRLAAWLVANELY 473

Query: 502 TSRTRLYIKGN---GIVDLPKLQEMVADVSHHFPLRLPAPTPKAL-YSPCEIRHLAIIVN 557
             R  L+++       + LP    +++ V   FP R     P +   SP ++    ++VN
Sbjct: 474 --RPGLHVQATLLPAPLTLPDCVGLLSAVHDLFPARATFNPPLSWGLSPEKVTAALLVVN 531

Query: 558 LEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTL-HFNGEQSM 616
           +    TA    +                       S+D LY  SW E   L    G +S+
Sbjct: 532 M----TAPREERAT--------------------VSIDTLYATSWGEFFHLERTTGLESL 567

Query: 617 -IEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTR 653
            I     ++  M     P   ++VF  ++ L   +R  
Sbjct: 568 GISPRDYLIDSMGLTLDPDARIKVFAPAKSLCQAVRRA 605


>UniRef50_D2L1I3 Putative adenylate cyclase n=1 Tax=Desulfovibrio sp. FW1012B
            RepID=D2L1I3_9DELT
          Length = 1281

 Score =  462 bits (1190), Expect = e-128,   Method: Composition-based stats.
 Identities = 142/668 (21%), Positives = 256/668 (38%), Gaps = 45/668 (6%)

Query: 3    LYIETLKQRLDAI---NQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPK 59
            L+   +++R  A+   N+ R+  A   +G A      +LP L+                 
Sbjct: 640  LFSRDIRRRRLALLANNKRRLAWARRRLGEAGAAFLDMLPGLVGLGLVRDGSGTRPAPGA 699

Query: 60   GICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWV 119
             I  + PD     +L         +  + P   L +  VYT+GS  +V Q+  SDLD+W+
Sbjct: 700  RIAGFAPDLPTLRHLVRHFGCPAAAFPEVPANALAVEAVYTIGSVGTVAQTSDSDLDVWI 759

Query: 120  CHQSWLDS-EERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGST 177
            C +    +  +      K   +  +A +  G+E+ FF +     R N  G    E  GS 
Sbjct: 760  CLKDGEAAHPDLPAFTDKLETISRFAETEAGLEIHFFCMTVQDVRDNVFGYSEDEGYGSA 819

Query: 178  QHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWLDLGGLS 236
            Q  LL +EFYRTA+ +AG++  W  VP    +E Y   +  +         + LD G ++
Sbjct: 820  QGCLLKEEFYRTALVVAGRKPAWWCVPARIGQEAYAKALSGIRRAEPEVAADCLDFGPVT 879

Query: 237  SLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVS 296
            +++ +EYFGASLW + KS+ SP+K+++K  LLE Y+     P LL   +K  +   +   
Sbjct: 880  AIAGDEYFGASLWMIVKSLTSPFKSIIKFGLLEKYAEHPGEPELLCDTLKDYVFANQGGL 939

Query: 297  FGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVS 356
            +  DPY ++   V+ +    +    ++L+R+ F  K       E A       +L     
Sbjct: 940  WRCDPYALLFREVSRHYQERKQSGAVELLRQAFLQKTGFDPCEEYATRSGET-ILDHFFP 998

Query: 357  EWGWDEARLAMLDNRANWK----IDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASP 412
                          R +        Q     + +    +++Y  L   ++        + 
Sbjct: 999  YAPPAAGACPPPPRRDSQADEDGFAQAVALGDAITAYFLRAYERLKARSQELASGGGLTE 1058

Query: 413  QDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPN 472
            +D  +L+R++ A+F    GK+  + P I P         I          G+ +   +  
Sbjct: 1059 RDQTMLSRRIAASFGRRVGKIMRM-PFIRPGRDLFASLEIACEEISPREKGFVIRAESAG 1117

Query: 473  IESIIS-HQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGN---GIVDLPKLQEMVADVS 528
             +      + +     L +L  W   N L   R  L+++       + LP +  ++  V 
Sbjct: 1118 PDRKARKRETVRQEGSLPRLAGWLTANELY--RPGLHLQAAALPAPLTLPDVAGVLGAVH 1175

Query: 529  HHFPLRLPAPTPKAL-YSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQ 587
            + FP+R       +L   P  +     +VNL     A    +                  
Sbjct: 1176 NVFPVRETFAPALSLGLLPERVTAALFVVNL----LAPREERRT---------------- 1215

Query: 588  NCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALK--TILGKMHQDAAPPDSVEVFCYSQH 645
                 S+D+LY  +W E+  L       + +A     +   +    AP   +EV+  ++ 
Sbjct: 1216 ----VSLDVLYATTWGELFHLERTAGLDVFDASPSLFLSESLGLALAPDLRLEVYAPARS 1271

Query: 646  LRGLIRTR 653
                 R  
Sbjct: 1272 QCQAGRQA 1279


>UniRef50_D1U9E3 Putative adenylate cyclase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
            RepID=D1U9E3_9DELT
          Length = 1291

 Score =  455 bits (1170), Expect = e-126,   Method: Composition-based stats.
 Identities = 150/624 (24%), Positives = 245/624 (39%), Gaps = 50/624 (8%)

Query: 3    LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGIC 62
            L     +QR+   N+ R+ RA+  +    Q    +LP LL          L+G  P  + 
Sbjct: 659  LTFMRREQRIQGFNRKRLVRAMGRLDRDKQAYLRMLPHLLETDVFETRFTLEGVPPCEVW 718

Query: 63   LYTPDETQRHYLNELELYRGMSVQDPPKG---ELPITGVYTMGSTSSVGQSCSSDLDIWV 119
             YTP       L+ +EL R    +  P G    + I  VY MGS  +V Q+  SD+D WV
Sbjct: 719  GYTPT------LSAMELTRQFFPKIRPSGTRARVRILAVYAMGSLGTVAQTAQSDIDCWV 772

Query: 120  CHQSWLDSEERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQ 178
            C    +D      L+RK   L  WA S  G+E  FF +  +  R N   S   E  GS Q
Sbjct: 773  CFDGDIDPNAEAGLRRKLDALGLWAESEFGIEAHFFPMRMDDVRDNRFSSGDEESSGSAQ 832

Query: 179  HILLLDEFYRTAVRLAGKRILWNMVPCDEEE-HYDDYVMTLYAQGVLTPNEWLDLGGLSS 237
             +LL +EFYRTAVR+AGK + W ++P   ++  YD  + +     V+      D G L+ 
Sbjct: 833  ALLLKEEFYRTAVRIAGKHLAWWVIPAGADKPTYDACIQSARRYPVMGRPRLEDFGHLAP 892

Query: 238  LSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSF 297
            +  +EYFG SLWQ+ K++ SP+K+VLK  LLE Y+    +P  L   IK+ L      + 
Sbjct: 893  VPPDEYFGGSLWQMVKAVHSPFKSVLKLGLLETYADPATSPLPLCDRIKRNLFLNRRGTR 952

Query: 298  GLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEK-----LSRERACVGWRRAVLS 352
              DPY  +   +  Y   + D     L+   F  K   +     L R          +++
Sbjct: 953  RTDPYASLFSTLRAYYADLGDAEAARLLTESFIFKANLRDILFFLGRPARAEDMS--LVA 1010

Query: 353  QLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLS-VSAS 411
             L      +  +    +    W  ++  +    +   M+ +Y  + +    +  +    +
Sbjct: 1011 TLFGRECAEPEQRCHTN--VAWTFEKSLKMGASVRRYMVATYERIQQGLSGSGRTDAQIN 1068

Query: 412  PQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAP 471
             +D+  + R++ A F   P KV  V P +        +           +  W +   + 
Sbjct: 1069 AEDLTRMGRRIAANFSPRPHKVMRV-PFMDAAGGGFAILHFSASKAPGRKPAWLVRGGSR 1127

Query: 472  NIESIISH--QPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGN-GIVDLPKLQEMVADVS 528
            +   + S   Q L  +     ++AW   N L + R+ L        + L  LQ+++  + 
Sbjct: 1128 SEAKLASSSLQLLHKSGDPVHMLAWLLANRLYSPRSLLQGDRTMAPISLADLQKLMPAMH 1187

Query: 529  HHFPLRLPAPTP-KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQ 587
              FP             S   +     I NL   P +    Q                  
Sbjct: 1188 EFFPFDQTFERDINEGLSSERVIRAFFIFNLTTAPDSRRIEQA----------------- 1230

Query: 588  NCLVGSVDLLYRNSWNEVRTLHFN 611
                    ++Y  +W E+    F+
Sbjct: 1231 -------SIVYSTNWGEMYCRSFD 1247


>UniRef50_Q2LSY1 Adenylate cyclase n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LSY1_SYNAS
          Length = 653

 Score =  416 bits (1069), Expect = e-114,   Method: Composition-based stats.
 Identities = 154/638 (24%), Positives = 274/638 (42%), Gaps = 62/638 (9%)

Query: 9   KQRLDAINQLRVDRALAAMGPA-FQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPD 67
           K      N+ R  R  + + P   + +  LLP +L  +   +PGY+D ++ +   ++  +
Sbjct: 32  KSIFLEYNRFR-KRLFSELAPKDSEIILYLLPWMLSVNDVSIPGYVD-HIKQNFRVFNIE 89

Query: 68  ------ETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC- 120
                 + +R +     +   ++V  P +  LP+ G+YT+GS  ++ Q+ SSD D+W+C 
Sbjct: 90  TEKDILKRERLFKKTFHIRNDLTVLKPAEKSLPVEGIYTIGSVGTISQTSSSDCDLWICI 149

Query: 121 HQSWLDSEERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQH 179
            ++  D E   LL  K   +++W  S L + V FFL D    R    G +  E CGSTQ 
Sbjct: 150 DKTLYDEEAFDLLTLKIDRIKDWMDSRLKMPVCFFLCDVEDIRACRFGGVDCESCGSTQK 209

Query: 180 ILLLDEFYRTAVRLAGKRILWNMVPCDEEEH--YDDYVMTLYAQGVLTPNEWLDLGGLSS 237
            +L +EFYRTA+  AGK  LW  V  D  +   YDD V   +        + +DLG L  
Sbjct: 210 KVLKEEFYRTAILTAGKIPLWW-VAWDRRQTLCYDDAVRE-WQSAPSVYYDLIDLGNLDF 267

Query: 238 LSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSF 297
           +   E FGA+LWQ  KS+  P K++LK LLL     E P   LL    ++ + D      
Sbjct: 268 IDKRESFGAALWQFNKSLTHPLKSILKMLLL-KMFLESPKEELLCHRFRRLILDQPRKPH 326

Query: 298 G-LDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVS 356
             +DP    L  V ++   ++  T L  + +CFYL+   KL      V    A+  +L  
Sbjct: 327 SFVDPGAFTLIAVLDFYQNMDPQT-LQFILKCFYLRYKVKLFSRTMTVKEETAL--ELFR 383

Query: 357 EWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIG 416
            +G D   +  L+  ++W           ++  ++  Y+++   AR   ++   + QD+ 
Sbjct: 384 RYGLDRETIYELNRFSSWTYSSQIRFGEFIVLLLVDIYKDIAHIARD--VTGDVAAQDLT 441

Query: 417 VLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESI 476
           +L +KL A+ +  P K+ +++  +   L  P+LT       R   + W ++    +   I
Sbjct: 442 ILGQKLSASLKKKPHKIPVLSKPLET-LKMPSLTL------RFCENRWQVFPDNDDGAMI 494

Query: 477 ISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGI-VDLPKLQEMVADVSHHFPLR- 534
           +  + L Y       +AW   N L     +L +  N     + ++  ++  +   F +  
Sbjct: 495 VEKRDLVYC---LAYLAW---NDLYFPG-QLRMLPNPTSAAMQEIINLLQKIREVFGVYD 547

Query: 535 LPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSV 594
           + +   +    P     L II+N    P A                         ++ ++
Sbjct: 548 VSSIDFQNFLQPEHTEKLLIIINFAAPPHAD------------------------VIHTL 583

Query: 595 DLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAA 632
            ++  N+W E+    F  ++  I  L+ I    +    
Sbjct: 584 SVIRLNNWGELFVNRFTLQERFISFLENIAESSYNTVE 621


>UniRef50_UPI00019102CE adenylate cyclase n=2 Tax=Salmonella enterica subsp. enterica
           serovar Typhi RepID=UPI00019102CE
          Length = 186

 Score =  306 bits (785), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 180/186 (96%), Positives = 182/186 (97%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPSG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           IC YTPDETQRHYLNELELYRGM+ QDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC
Sbjct: 61  ICFYTPDETQRHYLNELELYRGMTPQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           HQSWLD EERQLLQRKCSLLE+WAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI
Sbjct: 121 HQSWLDGEERQLLQRKCSLLESWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180

Query: 181 LLLDEF 186
           LLLDEF
Sbjct: 181 LLLDEF 186


>UniRef50_C0ARX6 Putative uncharacterized protein n=1 Tax=Proteus penneri ATCC 35198
           RepID=C0ARX6_9ENTR
          Length = 248

 Score =  279 bits (715), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 177/228 (77%), Positives = 198/228 (86%), Gaps = 1/228 (0%)

Query: 340 ERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIR 399
           +    GWRR VLSQLV++W WD  RL +LD R +WKI++VR+AHNELLD MMQSYRNLIR
Sbjct: 10  QNESEGWRRQVLSQLVTQWQWDNERLTILDTRDSWKIERVRDAHNELLDTMMQSYRNLIR 69

Query: 400 FARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRA 459
           FARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSE +LTFIYVP GRA
Sbjct: 70  FARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSESHLTFIYVPQGRA 129

Query: 460 NRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLP 518
           NRSGWYLYNRAP+ E+I+ HQPLEYNRYLNKLVAW++FNGLLT  +R+YI +G    D  
Sbjct: 130 NRSGWYLYNRAPDFENIVGHQPLEYNRYLNKLVAWSYFNGLLTKESRVYIHQGESSCDEI 189

Query: 519 KLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF 566
           KL E+V D+S HFP+RLPAPTPKALYSPCEIRHLAIIVNLE DPT +F
Sbjct: 190 KLHELVRDMSSHFPIRLPAPTPKALYSPCEIRHLAIIVNLETDPTESF 237


>UniRef50_D1U0N4 Conserved domain protein n=1 Tax=Yersinia pestis KIM D27
           RepID=D1U0N4_YERPE
          Length = 223

 Score =  257 bits (656), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 132/171 (77%), Positives = 148/171 (86%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLRVDRALAAMGPAFQ+VYSLLP LLH HHP MPGYLDGNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQKVYSLLPILLHCHHPQMPGYLDGNVPHG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           +CL+TP+E Q+ YL ++E   G  +     GELPITGVY+MGSTSS+GQ  +SDLDIWVC
Sbjct: 61  VCLFTPNEIQQDYLADVEARWGEPLAPSAGGELPITGVYSMGSTSSIGQCHTSDLDIWVC 120

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGG 171
           HQ+WLD+EER  LQ+KCSLLE WAAS+GVEVSFFL+DENRFRHN SGSLGG
Sbjct: 121 HQAWLDTEERNQLQQKCSLLEKWAASMGVEVSFFLVDENRFRHNASGSLGG 171


>UniRef50_C4TXU8 Putative uncharacterized protein n=4 Tax=Enterobacteriaceae
           RepID=C4TXU8_YERKR
          Length = 149

 Score =  198 bits (503), Expect = 9e-49,   Method: Composition-based stats.
 Identities = 112/145 (77%), Positives = 128/145 (88%)

Query: 700 LENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYI 759
           +ENA+EFYGAIS+NKLHGLS+QVE + + LP VVDGFASEGIIQFFFE T DE GFNIYI
Sbjct: 1   MENAVEFYGAISNNKLHGLSIQVEADQIHLPPVVDGFASEGIIQFFFEGTADEKGFNIYI 60

Query: 760 LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQ 819
           LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIV++DGR Q
Sbjct: 61  LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVQLDGRTQ 120

Query: 820 VIPFRTKSIGNMPPANQDHDTPLLQ 844
           VIPFR+ ++ ++  A+++   P  Q
Sbjct: 121 VIPFRSNALSHLHIADKETSAPAQQ 145


>UniRef50_A4P0R1 Adenylate cyclase n=2 Tax=Haemophilus influenzae
          RepID=A4P0R1_HAEIN
          Length = 102

 Score = 63.9 bits (154), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 23/56 (41%), Positives = 34/56 (60%)

Query: 1  MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGN 56
          M   +   KQ + A++Q R +RAL   G AFQ V +++P LLH +HP +PGY+   
Sbjct: 1  MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAVIPLLLHLNHPQLPGYVIHA 56


>UniRef50_UPI000169845A putative adenylate cyclase n=1 Tax=Endoriftia persephone
           'Hot96_1+Hot96_2' RepID=UPI000169845A
          Length = 255

 Score = 63.1 bits (152), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 29/181 (16%), Positives = 62/181 (34%), Gaps = 9/181 (4%)

Query: 649 LIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYG 708
            +  R+  L    +     + +   G   A R+S   + +  +      + L++   F  
Sbjct: 46  QVAQRLTGLYRHILG--YFNQQPGHGGRYAFRISEAFYLIQQKEQGFQWRNLDSFEHFLQ 103

Query: 709 AISHNKLHGLSVQVETNHV-KLP-AVVDGFASEGIIQFFFEETQDENGFNIYILDESNRV 766
           A+   +     +Q++   + + P   +       +IQ FF   +      IY+LDE   +
Sbjct: 104 ALETPQHVFQPLQIDPRILRQTPYPALYRHNKPDLIQLFFHVQR--ESVQIYLLDEQGAL 161

Query: 767 EVYHHCEGSKEELVRDVSRFYSSSHDRFTY--GSSFINFNLPQFYQIVKVD-GREQVIPF 823
                   S   ++    RF +S         G +       +FY++ +   G   +   
Sbjct: 162 FRQSMLMDSPRFMMLQQRRFLNSLQQLRLMLPGGAGNLLAETEFYELKQAPSGDWSIERR 221

Query: 824 R 824
           R
Sbjct: 222 R 222


>UniRef50_UPI0001699E12 hypothetical protein Epers_06677 n=1 Tax=Endoriftia persephone
          'Hot96_1+Hot96_2' RepID=UPI0001699E12
          Length = 77

 Score = 52.3 bits (124), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 21/60 (35%), Positives = 37/60 (61%)

Query: 5  IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
          ++ ++QR   +++ R+ R L  + P  Q +  LLP L H +HP++PGY++  VP GI  +
Sbjct: 18 LKIIRQRFQRLHRERLRRILGELRPTQQDLLQLLPLLFHINHPVLPGYINSKVPAGIPDF 77


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_D2TCR5 CyaA protein n=3 Tax=Erwinia RepID=D2TCR5_ERWPY      1120   0.0  
UniRef50_Q59685 Adenylate cyclase n=330 Tax=cellular organisms R...  1103   0.0  
UniRef50_C4LDV3 Adenylate cyclase n=2 Tax=Gammaproteobacteria Re...   971   0.0  
UniRef50_A0Y9E5 Adenylate cyclase, class I n=1 Tax=marine gamma ...   947   0.0  
UniRef50_A1SR20 Adenylate cyclase n=3 Tax=Psychromonas RepID=A1S...   937   0.0  
UniRef50_Q21EM4 Adenylate cyclase n=1 Tax=Saccharophagus degrada...   915   0.0  
UniRef50_Q2SQ66 Adenylate cyclase n=1 Tax=Hahella chejuensis KCT...   909   0.0  
UniRef50_C5BLM3 Adenylate cyclase, class I n=1 Tax=Teredinibacte...   901   0.0  
UniRef50_Q1N416 Adenylate cyclase n=1 Tax=Bermanella marisrubri ...   897   0.0  
UniRef50_A1TXX4 Adenylate cyclase n=2 Tax=Marinobacter RepID=A1T...   897   0.0  
UniRef50_P40134 Adenylate cyclase n=25 Tax=Pasteurellaceae RepID...   894   0.0  
UniRef50_A4BK19 Adenylate cyclase, class I n=1 Tax=Reinekea blan...   893   0.0  
UniRef50_Q1I310 Adenylate cyclase n=23 Tax=Pseudomonas RepID=Q1I...   875   0.0  
UniRef50_B3H1T6 Adenylate cyclase n=12 Tax=Pasteurellaceae RepID...   850   0.0  
UniRef50_A1SAP9 Adenylate cyclase n=18 Tax=Shewanella RepID=A1SA...   780   0.0  
UniRef50_Q088L2 Adenylate cyclase n=1 Tax=Shewanella frigidimari...   768   0.0  
UniRef50_B3PH57 Adenylate cyclase, class I n=1 Tax=Cellvibrio ja...   711   0.0  
UniRef50_C8R2N0 Putative adenylate cyclase n=1 Tax=Desulfurivibr...   595   e-168
UniRef50_B4RT26 Adenylate cyclase, class I n=2 Tax=Alteromonas m...   595   e-168
UniRef50_D2L1I3 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   574   e-162
UniRef50_Q1NP63 Adenylate cyclase n=2 Tax=delta proteobacterium ...   571   e-161
UniRef50_D1U9E3 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   566   e-159
UniRef50_C4XU05 Putative uncharacterized protein n=1 Tax=Desulfo...   566   e-159
UniRef50_C6BYH9 Putative adenylate cyclase n=1 Tax=Desulfovibrio...   561   e-158
UniRef50_C0N363 Putative uncharacterized protein n=1 Tax=Methylo...   555   e-156
UniRef50_C0QEU2 CyaA2 n=1 Tax=Desulfobacterium autotrophicum HRM...   540   e-152
UniRef50_C0ARX7 Putative uncharacterized protein n=1 Tax=Proteus...   510   e-143
UniRef50_Q2LSY1 Adenylate cyclase n=1 Tax=Syntrophus aciditrophi...   490   e-137
UniRef50_UPI00019102CE adenylate cyclase n=2 Tax=Salmonella ente...   295   5e-78
UniRef50_C0ARX6 Putative uncharacterized protein n=1 Tax=Proteus...   280   1e-73
UniRef50_D1U0N4 Conserved domain protein n=1 Tax=Yersinia pestis...   249   4e-64
UniRef50_C4TXU8 Putative uncharacterized protein n=4 Tax=Enterob...   181   9e-44
UniRef50_UPI000169845A putative adenylate cyclase n=1 Tax=Endori...   132   7e-29
UniRef50_A4P0R1 Adenylate cyclase n=2 Tax=Haemophilus influenzae...    73   4e-11
UniRef50_UPI0001699E12 hypothetical protein Epers_06677 n=1 Tax=...    60   5e-07

Sequences not found previously or not previously below threshold:

UniRef50_B8R1B0 DNA-directed RNA polymerase n=2 Tax=Volvox carte...    48   0.002


CONVERGED!
>UniRef50_D2TCR5 CyaA protein n=3 Tax=Erwinia RepID=D2TCR5_ERWPY
          Length = 887

 Score = 1120 bits (2896), Expect = 0.0,   Method: Composition-based stats.
 Identities = 698/831 (83%), Positives = 768/831 (92%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           +YLYIETLKQRLDAINQLRVDRALAAMG AFQQVYSLLPTLLHYHHPLMPGYL+GNVP G
Sbjct: 37  LYLYIETLKQRLDAINQLRVDRALAAMGSAFQQVYSLLPTLLHYHHPLMPGYLEGNVPHG 96

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           I  YTPDE+Q  YL+ LE   G     PP GE+P+TGVY+MGSTSSVGQ+ +SDLDIWVC
Sbjct: 97  ISFYTPDESQLSYLHGLEGQSGSDAAVPPHGEMPVTGVYSMGSTSSVGQNGTSDLDIWVC 156

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           HQSWLD++ER  LQ+KC LL+NW   +GVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI
Sbjct: 157 HQSWLDNDERLSLQKKCILLQNWCVEMGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 216

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLLDEFYRTAVR+AGKRILWNMVP +EEE YDDYVM+LY +GVLTPNEWLDLGGL +LSA
Sbjct: 217 LLLDEFYRTAVRMAGKRILWNMVPREEEEQYDDYVMSLYQRGVLTPNEWLDLGGLGTLSA 276

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
           EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP+ RLLA DIKQRLHDGEIVS+GLD
Sbjct: 277 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPDTRLLAMDIKQRLHDGEIVSYGLD 336

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGW 360
           PYCMMLERVT YL  I+D  RLDLVRRCFYLKVCEKLS      GWRR +LSQLV EWGW
Sbjct: 337 PYCMMLERVTRYLIGIDDPARLDLVRRCFYLKVCEKLSLAAENSGWRREILSQLVQEWGW 396

Query: 361 DEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR 420
           D+ RLAMLD+RA WKI QVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR
Sbjct: 397 DKQRLAMLDSRAGWKIGQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR 456

Query: 421 KLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQ 480
           KLYAAFEALPGKVTL+NPQISPDLSE +LTFI+VP GRANR+GWYLYN++P+++SIISHQ
Sbjct: 457 KLYAAFEALPGKVTLLNPQISPDLSESDLTFIHVPNGRANRAGWYLYNQSPDMDSIISHQ 516

Query: 481 PLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTP 540
           PLEYNRYLNKLVAWAWFNGLLTS+TRL+IKGN   DL +LQE+VADV+HHFP+RL APT 
Sbjct: 517 PLEYNRYLNKLVAWAWFNGLLTSKTRLHIKGNESCDLARLQELVADVTHHFPVRLAAPTA 576

Query: 541 KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRN 600
           KALYSPCEIRHLAII+NLE DPTAAFRNQVVHFDFRKLDVFSFG+ Q CLVGSVDLLYRN
Sbjct: 577 KALYSPCEIRHLAIIINLEVDPTAAFRNQVVHFDFRKLDVFSFGQQQQCLVGSVDLLYRN 636

Query: 601 SWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSE 660
           SWNEVRTLHFNGEQSMIEALKTILGKMHQDA+PPDSV+VFCYSQHLRGLIRTRVQQLVSE
Sbjct: 637 SWNEVRTLHFNGEQSMIEALKTILGKMHQDASPPDSVDVFCYSQHLRGLIRTRVQQLVSE 696

Query: 661 CIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSV 720
           C+ELRLSSTRQE GRFKALRV+GQTWGLFFERL+VSVQKLENA+EFYGAIS+NKLHGLS+
Sbjct: 697 CVELRLSSTRQEPGRFKALRVAGQTWGLFFERLSVSVQKLENAVEFYGAISNNKLHGLSL 756

Query: 721 QVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELV 780
           +VE++  +LPAVV+G+ASEGIIQFFFE+T++++GFNIYILDE+NRVEVYHHCEGSKEELV
Sbjct: 757 KVESDQARLPAVVNGYASEGIIQFFFEDTRNDHGFNIYILDETNRVEVYHHCEGSKEELV 816

Query: 781 RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNM 831
           RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIV+V+ R +VIPFR++++  +
Sbjct: 817 RDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVQVEERCEVIPFRSQAMTQL 867


>UniRef50_Q59685 Adenylate cyclase n=330 Tax=cellular organisms RepID=CYAA_PROMI
          Length = 865

 Score = 1103 bits (2853), Expect = 0.0,   Method: Composition-based stats.
 Identities = 649/854 (75%), Positives = 728/854 (85%), Gaps = 11/854 (1%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLR++RA A+M   F+QVY L+P LLHYHHP +PGY+ GNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRLERAFASMSDVFKQVYGLIPVLLHYHHPQLPGYIQGNVPHG 60

Query: 61  ICLYTPDETQRHYLNEL-ELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWV 119
            C + PD+ QR ++N+L        +     GELPITG+Y+MGSTSS+GQS  SD+DIWV
Sbjct: 61  TCFFEPDDVQRQWVNKLTNASCDEPMNGYTSGELPITGIYSMGSTSSIGQSHCSDIDIWV 120

Query: 120 CHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQH 179
           CHQSWLD +ER  LQRKC L+E WA  LG++V+FFLIDENRFRH+ SGSLGGEDCGSTQH
Sbjct: 121 CHQSWLDQDERARLQRKCLLIEQWAGELGIDVTFFLIDENRFRHHASGSLGGEDCGSTQH 180

Query: 180 ILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLS 239
           ILLLDEFYRTAVRLAGKR+LW MVP +EE HYD+YV +LYAQGVLTPNEWLDLGGL  LS
Sbjct: 181 ILLLDEFYRTAVRLAGKRLLWTMVPVEEEYHYDEYVNSLYAQGVLTPNEWLDLGGLGELS 240

Query: 240 AEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGL 299
           AEEYFGASLWQLYKS+DSPYKAVLK++LLEAYS +YPN +LLA ++KQ LH GEIV++GL
Sbjct: 241 AEEYFGASLWQLYKSVDSPYKAVLKSILLEAYSADYPNGKLLALEMKQHLHRGEIVNYGL 300

Query: 300 DPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS---RERACVGWRRAVLSQLVS 356
           D YCMMLERVT YL +I D TRLDL+RRCFYLKVCEKLS    E    GWRR VLSQLV+
Sbjct: 301 DAYCMMLERVTRYLVSINDLTRLDLIRRCFYLKVCEKLSNEKNENEPAGWRRQVLSQLVT 360

Query: 357 EWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIG 416
           +W WD  RLA+LDNR +WKI++VR AHNELLD MMQSYRNLIRFARRNNLSVSASPQDIG
Sbjct: 361 QWQWDHERLAILDNRDSWKIERVRNAHNELLDTMMQSYRNLIRFARRNNLSVSASPQDIG 420

Query: 417 VLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESI 476
           VLTRKLYAAFEALPGKVTLVNPQISPDLSEP+LTFIYVPPGRANRSGWYLYNRAP+   I
Sbjct: 421 VLTRKLYAAFEALPGKVTLVNPQISPDLSEPHLTFIYVPPGRANRSGWYLYNRAPDFAHI 480

Query: 477 ISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRL 535
           + HQPLEYNRYLNKLVAW++FNGLLT  +++YI +G+   D  KL E+V D+S HFP+RL
Sbjct: 481 VGHQPLEYNRYLNKLVAWSYFNGLLTKDSQVYIHQGDSSCDEIKLHELVRDISSHFPIRL 540

Query: 536 PAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVD 595
           PAPTPKALYSPCEIRHLAIIVNLE DPT  F +QVVHFDFRKLDVFSFGE + CL+GS+D
Sbjct: 541 PAPTPKALYSPCEIRHLAIIVNLEVDPTERFSDQVVHFDFRKLDVFSFGEEEQCLIGSID 600

Query: 596 LLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQ 655
           LLYRNSWNEVRTLHFNG QSM+E+LKTILGKMHQDAAPP SVEVFCYSQHLRGLIRTRVQ
Sbjct: 601 LLYRNSWNEVRTLHFNGTQSMLESLKTILGKMHQDAAPPASVEVFCYSQHLRGLIRTRVQ 660

Query: 656 QLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKL 715
           QLVSECIELRLS+ R E GRFKALR++GQTWGLFFERLNVSVQKLENAIEFYGAIS+NKL
Sbjct: 661 QLVSECIELRLSTNRLEPGRFKALRIAGQTWGLFFERLNVSVQKLENAIEFYGAISYNKL 720

Query: 716 HGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGS 775
           HGL V++  +   LPAV+DGFA EGIIQFFFE T+D N FNIYILDE+NRVE+Y HCEGS
Sbjct: 721 HGLPVKLGKDARYLPAVIDGFACEGIIQFFFETTEDNNVFNIYILDEANRVEIYSHCEGS 780

Query: 776 KEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMP--- 832
           KEELV+DVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDG  QV+PF   S G +    
Sbjct: 781 KEELVKDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGATQVLPFAGGSFGKLSDLG 840

Query: 833 ---PANQDHDTPLL 843
              P  +    P+ 
Sbjct: 841 KTAPKEEMSTKPIQ 854


>UniRef50_C4LDV3 Adenylate cyclase n=2 Tax=Gammaproteobacteria RepID=C4LDV3_TOLAT
          Length = 830

 Score =  971 bits (2510), Expect = 0.0,   Method: Composition-based stats.
 Identities = 419/835 (50%), Positives = 570/835 (68%), Gaps = 13/835 (1%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           M+   E L  R DAINQ++++RAL AM  A +++ S+LP LLHYHHP +PGY+ G VP G
Sbjct: 1   MFKQFELLVARCDAINQIKMERALEAMNEAGRRMLSMLPVLLHYHHPHLPGYVSGEVPCG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           I  + PD  QR +L      +     +P   E  ++ VYTMGSTSS+GQS  SDLDIW+C
Sbjct: 61  IANFQPDAAQRKFL----FTQCGHTAEPEVKECCLSAVYTMGSTSSIGQSTVSDLDIWIC 116

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           H   L +E R LL++KC  L   A    VE++FFLI EN+FR      +G ++CGS QH+
Sbjct: 117 HDPALSAERRALLEQKCQFLSRLAEQHSVEMNFFLIPENKFRVGNQAQVGLDNCGSAQHL 176

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLL+EFYR+A R+AGKR+LW ++P + E+ YD     L++ G+++ ++WLDLGG+  + A
Sbjct: 177 LLLEEFYRSATRVAGKRLLWPLIPVEREDEYDALAAALFSTGMISEDDWLDLGGVGHIPA 236

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
           EEYFG++LW LYK +DSPYKAVLK L++EAYS E+P+  LLA   K+     +     LD
Sbjct: 237 EEYFGSALWLLYKGLDSPYKAVLKILVMEAYSAEFPHTDLLAVQAKRWFQQHDEFGLSLD 296

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVG--WRRAVLSQLVSEW 358
            Y +ML++VT+YLT + D  RLDL RRCFYLK+C+ LSR        WRR +L +LV +W
Sbjct: 297 AYYLMLDKVTDYLTKLGDTKRLDLARRCFYLKICDPLSRNVPPQHGRWRRDLLVKLVRDW 356

Query: 359 GWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
           GWD A L  LD+   WK++QV+ A+ ELL ++MQSY  LI+FARRNN+S S +P+DIG+L
Sbjct: 357 GWDHATLQHLDSHDQWKVEQVKTAYEELLSSLMQSYSKLIQFARRNNISESINPEDIGIL 416

Query: 419 TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIIS 478
           +RKLY AFEALPGKV  +N +I+PDL E +L+ I VPPG  NR GWYLY  +     II 
Sbjct: 417 SRKLYTAFEALPGKVQRINLKIAPDLHESDLSLIQVPPGHLNRQGWYLYKYSLKPHDIIG 476

Query: 479 HQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGI-VDLPKLQEMVADVSHHFPLRLPA 537
             PLEYN YL+KLVAWA+FNGL+ + TR+ I+  G  +    L +   D++  FP+ LP 
Sbjct: 477 RAPLEYNGYLSKLVAWAYFNGLMVANTRIDIRQAGSDITRTCLHQFCQDLADTFPVELPP 536

Query: 538 PTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLL 597
            +  AL  PCEIRHL I +NLE DPTA +  ++        D+  FG  Q CL+G+VDL+
Sbjct: 537 ASNLALSRPCEIRHLGIFLNLERDPTADWPEEMPPVLEHGEDMLCFGARQECLIGTVDLV 596

Query: 598 YRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQL 657
           YRNSWNEVRTLHFNG  +++EAL TIL KMHQDAA PD+++VFCYSQ+ R  IR +  +L
Sbjct: 597 YRNSWNEVRTLHFNGLDAVVEALSTILSKMHQDAAAPDAIDVFCYSQYYRDEIRHQFTEL 656

Query: 658 VSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHG 717
           V+ CI LRL+  +Q     K L V    + LF ER  VSV++L +AI+FY  +S NKL  
Sbjct: 657 VNSCISLRLALDKQRM--VKLLSVGEHRYALFLERRGVSVRQLSSAIDFYRQVSDNKLER 714

Query: 718 LSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKE 777
            + + + N + +P +VD +ASEG+IQ+FFE+   +NGFN+YILDE+N+VE+YH   GSKE
Sbjct: 715 QTAEPD-NGLHVPPIVDAYASEGLIQYFFEDN--DNGFNVYILDENNKVEIYHEYAGSKE 771

Query: 778 ELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMP 832
           +LV++V+R+Y+ +H RF +    INFNLPQFY++V      QV P+R+ ++  MP
Sbjct: 772 DLVQNVNRYYTMTHQRFDFTEQVINFNLPQFYELVPGSDSLQVTPYRS-AMREMP 825


>UniRef50_A0Y9E5 Adenylate cyclase, class I n=1 Tax=marine gamma proteobacterium
           HTCC2143 RepID=A0Y9E5_9GAMM
          Length = 966

 Score =  947 bits (2448), Expect = 0.0,   Method: Composition-based stats.
 Identities = 270/870 (31%), Positives = 435/870 (50%), Gaps = 39/870 (4%)

Query: 3   LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGIC 62
             ++T+KQR   +N  R+ R  +A+G   Q    LLP + H +HP++PGY+    P G+ 
Sbjct: 18  KTLKTVKQRFLQVNNARLARTKSALGARQQIFLELLPMMFHVNHPMLPGYVSHQTPCGLD 77

Query: 63  LYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQ 122
            + P +  +       L R  + +  P     I G++ MGS+ SV QS  SDLDIW+CH 
Sbjct: 78  GFNPTK--KDVEKTQRLSRSFTYRRQPTMIRRINGIFLMGSSGSVAQSEKSDLDIWLCHP 135

Query: 123 SWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILL 182
             +  +E   L++K   +  WAA++G+EV FFL+++ +FR  E  +L  EDCGS+QH LL
Sbjct: 136 P-ISPDETLELKQKTEGISRWAATVGLEVHFFLMEDEKFRLGERETLSTEDCGSSQHYLL 194

Query: 183 LDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEE 242
           LDEFYRT + +AG+  +W ++P DEE+HY+ Y  TL  +  +  +E LD GG+  + A E
Sbjct: 195 LDEFYRTGLLIAGRIPIWWLIPPDEEKHYEHYAETLRKKRFVRGDETLDFGGVGHIPAGE 254

Query: 243 YFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPY 302
           + GA +WQLYK+IDSPYK+VLK LL E Y+ EYPN   L+   K+ ++D ++    LDPY
Sbjct: 255 FIGAGVWQLYKAIDSPYKSVLKILLTEVYAAEYPNVEPLSTSFKRAIYDNQLDIDELDPY 314

Query: 303 CMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKL--SRERACVGWRRAVLSQLVSEWGW 360
            ++  ++  YL A E+F RL+LVRRCFY KV + L  S +     W+R ++ +LV +W W
Sbjct: 315 VVVYRKLESYLLAREEFQRLELVRRCFYFKVGKSLTRSNKDTAKSWQRQLIEKLVGQWNW 374

Query: 361 DEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTR 420
            +A L  LD R  WK+ QV     +++  +  SYR ++ FARR   +   + Q++ +L R
Sbjct: 375 SDADLYRLDARNTWKVAQVITEQKQIVRELTNSYRFVLEFARRTRATAMINSQEMTILGR 434

Query: 421 KLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPG-----RANRSGWYLYNRAPNIES 475
           KLYAAFE   GK+  +NP I+  L E  LTF  V        +  +  W +         
Sbjct: 435 KLYAAFERKAGKIEWINPGIADSLIEDKLTFYQVQEHQITDAKNQKVFWAVTTEEIKSAD 494

Query: 476 IISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLR 534
           I    P+     L  L+AW  FN LL S TR+ I +G+  V   +LQ MV  +  +    
Sbjct: 495 ISEDIPVRKADELTTLIAWCHFNSLLDSTTRIAIVEGDHEVSEFELQSMVRSLRQNSATA 554

Query: 535 L-----PAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNC 589
                     P     P     + + +N+  DP A  R Q +     + D F +   +  
Sbjct: 555 KQYDNNDDEKPDRFSQPMRPMQIQLFINVGLDPLAHIRTQGIERLSAQTDSFGYSGLREN 614

Query: 590 LVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQ-DAAPPDSVEVFCYSQHLRG 648
           LV +V+ +  NSW EV +  ++GE ++I  L   L  +    ++    +++ C+      
Sbjct: 615 LVLNVEQVLVNSWGEVSSRRYDGEHALIRCLSDYLQMLPPGSSSALPQLDIRCFCLTRAS 674

Query: 649 LIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYG 708
            I++RV++L  +      +  R    R   L +  + + + F     ++ ++    E   
Sbjct: 675 AIKSRVEELFHDITACYYTGNRPANTR-YILEIQREYYVVQFADNYPTIDRVGTFDELLS 733

Query: 709 AISHNKLHGLSVQVETNHVKLPAV--VDGFASEGIIQFFFEETQDENGFNIYILDESNRV 766
            +S  +     + ++   +    +  +   +  G I  F++    ++  +IYILDE   +
Sbjct: 734 YLSKPQKSYSPIVLDRYCLNNSPLAAITQLSRAGKIHIFYQ--HHKSNADIYILDEKGSL 791

Query: 767 EVYHHCEGSKEELVRDVSRFYSSS------HDRFTYGSSFINFN----LPQFYQI----- 811
             Y      +  L+  + +F  S+       +    GSS   FN      ++Y+I     
Sbjct: 792 LHYTTPFFDERSLLGPLDQFIQSTLFRRASENHDAEGSSLNAFNSDDFTVEYYEITQTVS 851

Query: 812 -VKVDGREQVIPFRTKSIGNMP-PANQDHD 839
            VK+  RE V    T S  N+    +QD +
Sbjct: 852 AVKLIRREAVKEIHTGSFFNVQAIVDQDMN 881


>UniRef50_A1SR20 Adenylate cyclase n=3 Tax=Psychromonas RepID=A1SR20_PSYIN
          Length = 869

 Score =  937 bits (2422), Expect = 0.0,   Method: Composition-based stats.
 Identities = 383/862 (44%), Positives = 544/862 (63%), Gaps = 36/862 (4%)

Query: 4   YIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICL 63
            I+ L+ + D + +LR+  A   M      V+   P LLHY+HP +PGY  G+ P GI  
Sbjct: 12  EIKRLRDKADELTRLRIQSAELLMNADTLTVFRTFPLLLHYNHPSLPGYTKGDTPTGIHQ 71

Query: 64  YTPDETQRHYLNELE-------------------------LYRGMSVQDPPKGEL---PI 95
           +  ++ Q+  L EL                          L   +S QD P+ +     +
Sbjct: 72  FNVNKKQKKQLAELFPYQEEPQKKAQATNLITKPTDLKIQLNNLLSFQDEPQKKPQQADL 131

Query: 96  TGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFL 155
            G+Y MGST+S+GQS  SDLDIW+C+   +D +  QLL+ K  L+ +WA   GVE++FFL
Sbjct: 132 IGLYAMGSTASIGQSSESDLDIWICYPHQMDKQRVQLLKNKSWLITHWAEGYGVELNFFL 191

Query: 156 IDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYV 215
           I +N+FR +    +  + CG++QH+LLLDEFYRT + +AGKRILW  VP + E++Y++YV
Sbjct: 192 IPDNKFRIDNKSDMTMDACGTSQHLLLLDEFYRTELHIAGKRILWWQVPFEHEKNYNEYV 251

Query: 216 MTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEY 275
             LY  G L P++WLDLGG   + AEEYFGA+LWQLYK ID+PYKAVLKT+L+EAYSWEY
Sbjct: 252 KKLYDNGGLNPDDWLDLGGFDRIPAEEYFGATLWQLYKGIDTPYKAVLKTILMEAYSWEY 311

Query: 276 PNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCE 335
           PN  L+A   K+R  + +     LDPYC+MLE+VT YL  I DF RL++VR CFYLK  E
Sbjct: 312 PNTELIALYYKKRFQEQQTDLEYLDPYCLMLEKVTSYLNKINDFKRLEVVRACFYLKTEE 371

Query: 336 KLSR--ERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQS 393
            LS+        WRR VL++ V+ W W++  +A LDNR  WK+  V  A + LLD +M S
Sbjct: 372 NLSKICTLNPPTWRRQVLTKFVNRWDWNKDHIADLDNRKKWKVRAVSNAKDILLDTLMAS 431

Query: 394 YRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIY 453
           Y  L+RFAR NN+  S S +D+G+L+RKLYAA E+LPGKV L+NP+ISPDLSEP+L+FI 
Sbjct: 432 YSKLLRFARDNNIEGSISAEDLGILSRKLYAAHESLPGKVDLINPKISPDLSEPDLSFIQ 491

Query: 454 VPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNG 513
           VP  R N +GWYLYN + +  ++I+   L Y +Y+ KLVAW   NGL    T+L++   G
Sbjct: 492 VPKNRKNAAGWYLYNCSLDSFTLINTPTLMYAKYIAKLVAWCHMNGLYEEETQLHLYNQG 551

Query: 514 I-VDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVH 572
             +   KL + + D+   FP+ +P  +  AL  PCEI+HL I +NLE DPT  + +    
Sbjct: 552 SDLVDKKLNQFIQDLYSVFPIYIPKASNNALSRPCEIKHLTIFLNLERDPTRHWESTSES 611

Query: 573 FDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAA 632
            D ++ D+FS+GE++ CL+GS+DL+YRNSWNEVRTLHFN  QS+I+AL TILGKMHQ A 
Sbjct: 612 EDDQQGDIFSYGEDKECLIGSIDLIYRNSWNEVRTLHFNSNQSVIDALHTILGKMHQGAC 671

Query: 633 PPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFER 692
           PP+ +++FCYS   +  I    +  ++E I+LRL S  Q +   + L+   + +  +FE+
Sbjct: 672 PPEQIDLFCYSCQFQAQISQAFKSKLNEYIQLRLDSLSQRS--VQTLKTGEENFAFYFEQ 729

Query: 693 LNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHV-KLPAVVDGFASEGIIQFFFEETQD 751
             VSVQ L+N ++ Y  IS+ K+   ++ ++  +  K  +++    SEGI+QFFFE   D
Sbjct: 730 TGVSVQHLKNLVDIYSHISNKKVSNSALNLKNTYFDKTVSIIGSHISEGIVQFFFENYHD 789

Query: 752 ENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQI 811
             GFN+YI +  N +E  H   G K++LV++V+RFY+S+++        INFNLPQFY+I
Sbjct: 790 --GFNVYIANADNEIETLHSFTGGKDDLVQNVNRFYASNNNEMNKQDDRINFNLPQFYEI 847

Query: 812 VKVDGREQVIPFRTKSIGNMPP 833
              D +E ++   T +     P
Sbjct: 848 ELSDNKELILSSFTSTTKENEP 869


>UniRef50_Q21EM4 Adenylate cyclase n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21EM4_SACD2
          Length = 954

 Score =  915 bits (2365), Expect = 0.0,   Method: Composition-based stats.
 Identities = 241/851 (28%), Positives = 408/851 (47%), Gaps = 21/851 (2%)

Query: 4   YIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICL 63
            +  L++R  +IN  R++R  +A+    Q     LP L H +HP+MPG++  + P  +C 
Sbjct: 20  NLTLLRKRFLSINTDRLERMRSALNSHQQLCLDALPLLFHTNHPMMPGFVSRSTPARLCN 79

Query: 64  YTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQS 123
           + PD+        +   R  ++   P  E  I G+Y MGS  ++ QS SSDLDIW+CH+ 
Sbjct: 80  FKPDKDILQLGRRV--ARSFTLGYDPSLEEDIYGIYVMGSVGTIAQSESSDLDIWLCHKP 137

Query: 124 WLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLL 183
            L  +    L++KC+ +  WA SL +E+ FF +D   F+     +L  E  GS Q +LLL
Sbjct: 138 GLSKQAVDELEKKCTKISEWAMSLRLEMHFFTMDYEEFKRGTLSALNEESSGSAQRLLLL 197

Query: 184 DEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEY 243
           DEFYR+A+ L G+  LW  VP   E+ Y++Y  TL  +  L+ N  LD G ++++   E+
Sbjct: 198 DEFYRSAIFLGGRIPLWWFVPARAEKDYENYSSTLLDKRFLSDNLVLDFGDIATIPDGEF 257

Query: 244 FGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYC 303
            GA +WQLYK+I+SPYK+VLK LLLEAY  E+PN   L+   K+ +  GE+    LD Y 
Sbjct: 258 IGAGIWQLYKAIESPYKSVLKLLLLEAYVSEHPNIDPLSLSFKREVFAGEVDINNLDSYL 317

Query: 304 MMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERA--CVGWRRAVLSQLVSEWGWD 361
           ++  R+  YL   + + RL+L RRCFY KV + LSR        W+R ++ QLV +W W 
Sbjct: 318 IIYRRIERYLQQKQQYKRLELARRCFYFKVNKPLSRPSRSNTKSWQRVLMEQLVKDWEWS 377

Query: 362 EARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRK 421
           EA +A+LD R  WK + V    ++L+  +  SYR L+ FA    ++ + S  ++ +L RK
Sbjct: 378 EADIALLDKRKRWKTNTVAMERSQLVSELNHSYRFLLDFANNCGVAHAISSDELNILGRK 437

Query: 422 LYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQP 481
           L AAFE  PGK+  +NP IS DLSEP L  ++     A ++  +              + 
Sbjct: 438 LQAAFERRPGKIDWINPGISHDLSEP-LIALHSEYEEALKTTLWTAVTFDEDSPNAGGEA 496

Query: 482 LEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPK 541
           ++ +  + +L+ W ++NGL+ + TR  + G   ++  +L+ ++       P    +   +
Sbjct: 497 IKASPSVVELMLWCYYNGLIDNSTRFDLTGCEEINEYELRRLLNLFQQWLPQTTSSLPHE 556

Query: 542 ALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNS 601
                       +++N+   P +  ++        + D   +      LV SVD++ RNS
Sbjct: 557 TFKQSAVPSDAMLLINVAKHPMSQLQDHGYQRLSSRSDALRYSGFDENLVVSVDIVIRNS 616

Query: 602 WNEVRTLHFNGEQSMIEALKTILGKMHQDAAP-PDSVEVFCYSQHLRGLIRTRVQQLVSE 660
           WNE+ T  F  + ++++AL   L          P ++ V C  + L   I  RV+   +E
Sbjct: 617 WNEINTRRFEKDTALLDALHEYLQLCLPGTHHLPPALTVECVGETLSNTISQRVKDWFNE 676

Query: 661 CIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSV 720
            +    +  +    R     +    + L F  + +  +   N       +   +     +
Sbjct: 677 IVHCFYADKKAAN-RRYIFEMGNHYYCLQFSGMKLVTRAFTNPNALLAHLGEEQTKPSPI 735

Query: 721 QVETNHVKLPAV--VDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEE 778
            +++N + L  +  +        +  F+     + G  I+++DE   +  Y    G K+ 
Sbjct: 736 ILDSNALHLHPLRPICSHTKAQSVSVFYHRF--DIGMEIFVVDEKGSI-HYTLLRGCKDH 792

Query: 779 -LVRDVSRFYSSSHDRFTYGSSFINFN------LPQFYQIVKVDGREQVIPFRTKSIGNM 831
             ++ + RF  ++ +R     S   F+         FY++ K    +     +  S    
Sbjct: 793 NPLKSLHRFLRATINR--EARSNPAFSGDFGIFPIHFYELSKNITNQYGCVSKRISTELP 850

Query: 832 PPANQDHDTPL 842
            PA  D     
Sbjct: 851 SPALFDVKAIA 861


>UniRef50_Q2SQ66 Adenylate cyclase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2SQ66_HAHCH
          Length = 971

 Score =  909 bits (2350), Expect = 0.0,   Method: Composition-based stats.
 Identities = 260/827 (31%), Positives = 404/827 (48%), Gaps = 22/827 (2%)

Query: 5   IETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLY 64
           ++TL QR   + + R+ R   A+ P  Q V  LLP L H +HPL+PGY+    P  +  Y
Sbjct: 20  LKTLCQRFITLVEHRLQRTRLALTPRQQVVLELLPLLFHVNHPLLPGYVSRTTPHRLVNY 79

Query: 65  TPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSW 124
            PD+          L R  + ++P +    I  +Y MGST S+  S  SD D+W+CH+  
Sbjct: 80  EPDKNVV--AQAQRLSRSFNYREPARHHGDIASLYLMGSTGSIAHSGGSDFDVWLCHRPD 137

Query: 125 LDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSL-GGEDCGSTQHILLL 183
           LD+     LQRK  L+  WA  +G E+  FL+D   FR     +    EDCG+ QH LLL
Sbjct: 138 LDAMALMELQRKADLVCQWAMEMGSEMHIFLMDAEAFRSGRHDAAADSEDCGTAQHYLLL 197

Query: 184 DEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEY 243
           DEFYRT + L G   LW ++P D+E  Y D    L  +  + P +++D GG + + + E+
Sbjct: 198 DEFYRTGIWLGGAYPLWWLIPPDQEASYADLAELLLEKRFIKPKDYIDFGGCARIPSNEF 257

Query: 244 FGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYC 303
            GA +WQLYK IDSPYK+VLK +L+E+Y+ E      L+   KQ +    +    LDPY 
Sbjct: 258 VGAGMWQLYKGIDSPYKSVLKLMLVESYAKEEDTLPNLSLAYKQAIFADRLDPDELDPYV 317

Query: 304 MMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS--RERACVGWRRAVLSQLVSEWGWD 361
           M+  R+ + L +  +  RL+LVRR FYLK+ E+LS         WRR V+ +L  EW W 
Sbjct: 318 MVYRRLEQSLQSRREQGRLELVRRSFYLKIGERLSVFVPEREKSWRRKVMEKLTHEWEWS 377

Query: 362 EARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRK 421
           E  L  LD R+ WK+DQV +    +++ +   YR L  +AR   L+ + S +DI +L RK
Sbjct: 378 ERELRYLDGRSAWKVDQVIQEKRAVVNELTGCYRFLSSYAREKGLAAAISARDINLLGRK 437

Query: 422 LYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPG--RANRSGWYLYNRAPNIESIISH 479
           LYAAF+   GKV ++NP I+P+LSE NL F ++      A  +GW LY    N      +
Sbjct: 438 LYAAFQRKAGKVEMINPGIAPNLSEDNLAFHHLSSQAIGAAGNGWLLYRNLSNPMDAAFN 497

Query: 480 QPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRLPAP 538
             ++ +  L +L+ WA+ NGLL   T + +  G       +LQ++++ +     L LPA 
Sbjct: 498 PAVKRSNSLIELLVWAYCNGLLDRSTSVSLASGESHASQYELQQIISSLRSLISLPLPAV 557

Query: 539 TPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLY 598
           T +   +   +R   + VN+  DP A    + +H    + D   +   +  LV ++D + 
Sbjct: 558 TQQDYRAKARLRATLVYVNVGVDPMADLSRRGLHKLSNRNDALGYASERANLVVTLDQVI 617

Query: 599 RNSWNEVRTLHFNGEQSMIEALKTILGKM---HQDAAPPDSVEVFCYSQHLRGLIRTRVQ 655
            NSWNEV    +    ++++ LK  L  +    Q       + V CY     G I  RV 
Sbjct: 618 INSWNEVMVQRYESGDTLVQCLKNYLAALAESEQFGEGLPQLSVLCYCPTRAGAIAQRVN 677

Query: 656 QLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKL 715
           QL  + +    S   +   R   L++  + + L F         LE+ +     ++  + 
Sbjct: 678 QLFQQVVFCYFSDKERARSR-YILQMEDRYFVLQFVDDQPRFTALEDYVGLCEFLAQPQK 736

Query: 716 HGLSVQVETNHVK---LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHC 772
           H  S+ V+   +    L AV        +  F+  + +     +IY++DE   + VY   
Sbjct: 737 HYSSIVVDDYALSEDVLRAVFARMRPHAVQVFYLNQGRIT---DIYVIDEKGSLLVYRET 793

Query: 773 EGSKEELVRDVSRFYSSSHDRFTYGSSFIN----FNLPQFYQIVKVD 815
                 L+  + +F     +R     S  +    F   +FYQ+    
Sbjct: 794 GSDINVLLGSLKQFLLGVQERKQMHDSLADDGAGFLEVEFYQLQPGK 840


>UniRef50_C5BLM3 Adenylate cyclase, class I n=1 Tax=Teredinibacter turnerae T7901
           RepID=C5BLM3_TERTT
          Length = 961

 Score =  901 bits (2328), Expect = 0.0,   Method: Composition-based stats.
 Identities = 241/858 (28%), Positives = 397/858 (46%), Gaps = 28/858 (3%)

Query: 4   YIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICL 63
            +  +++R  AINQ R+ R   A+    Q V   +P L H +HP+MPG+   + P G+C 
Sbjct: 19  NLTKIRKRFLAINQDRLTRMRDALTVRQQLVLDAIPLLFHTNHPMMPGFESRDTPAGVCH 78

Query: 64  YTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQS 123
           +   +          + R  +       E  IT ++ MGS  ++ QS SSDLD W+C + 
Sbjct: 79  FKITKGAVQLGR--GIARSFTASQDAVHEPQITAIFVMGSVGTIAQSESSDLDFWLCFKP 136

Query: 124 WLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLL 183
            L  E+ +LL RKC  +  WA    +EV FFL+D   F+  +  +L  E  GS Q +LLL
Sbjct: 137 GLTREQLELLNRKCEKITQWALQCRLEVHFFLMDNAAFKRGQLSALNEESSGSAQRLLLL 196

Query: 184 DEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEY 243
           DEFYRTA+ LAG+  +W  VP   E  YD+Y   L  +  L   + LD GG+ ++   E+
Sbjct: 197 DEFYRTAIHLAGRTPIWWFVPPGNEHEYDEYTDILQQRRFLNSEDVLDFGGIPTIPDSEF 256

Query: 244 FGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYC 303
            GAS WQLYK I+SPYK+VLK LLLE+Y+ +YPN + L+   K+ ++ GE     LD Y 
Sbjct: 257 LGASRWQLYKGIESPYKSVLKLLLLESYADQYPNIQPLSLVFKEMVYAGEHDIDQLDSYV 316

Query: 304 MMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKL--SRERACVGWRRAVLSQLVSEWGWD 361
           M+   +  YL       RL+L RRCFY KV   L  S       W+  +L  L  EWGW 
Sbjct: 317 MIYRHIERYLQEKNAVRRLELARRCFYFKVNYPLTRSNPNRDKTWQHRLLESLTEEWGWQ 376

Query: 362 EARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRK 421
              L  LD R  WK   V E  + L + +   ++ L  FA R ++    S ++  +L RK
Sbjct: 377 RKDLLKLDQRNQWKAPAVHEERSLLKNELSHGFQVLKLFAERYSVEHDISAEEWSILGRK 436

Query: 422 LYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQP 481
           L AAFE  PGK+T +NP IS DL+E  +TF      R       +++   + +  ++  P
Sbjct: 437 LQAAFETRPGKITWINPGISSDLTEQLVTFAQSAVERPGN----IWSALIHPDGTLTQNP 492

Query: 482 LE--YNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPT 539
           +    +  L +L  W + N ++   TR  ++    ++   L  ++   ++  PL L +  
Sbjct: 493 IHIKTSASLVELYLWCYCNQIVNLTTRYELQQAPHIEERTLHRLLKVFANWLPLPLKSLD 552

Query: 540 PKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYR 599
                   E      ++N+     A    + +     + D   +      L+ SVDL+ R
Sbjct: 553 HNVFKRSAEPVDALFLLNVGSVAQAGLEQRGIKRLSSQTDALHYSGFGENLIISVDLVLR 612

Query: 600 NSWNEVRTLHFNGEQSMIEALKTILG-KMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLV 658
           NSWNE+ T  F+   +++++L+  L   +      P  ++V C S +    I TR +  +
Sbjct: 613 NSWNELTTRRFDSSTALLDSLQDYLKLSLPGSHHRPPKLQVECVSPNHANTIATRTRDWL 672

Query: 659 SECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGL 718
           +E I            R     ++G    L F+   +  ++  +      A+   +    
Sbjct: 673 NEIIHCYYGGEYMSATR-YVFEMAGLFHILQFKGPRLITRQYPSLDAVLDALGDAQPSIS 731

Query: 719 SVQVETNHV---KLPAVVDGFASE-------GIIQFFFEETQDENGFNIYILDESNRVEV 768
            + ++++ +    L A+    +SE       G I  FF+  QD    ++Y++DE   +  
Sbjct: 732 PIYLDSHALVRHPLKAMCRAISSEGGGRSWAGAIHIFFQRAQDHT--DVYVVDEHGSLVH 789

Query: 769 YHHCEGSKEELVRDVSRFYSSSHDRFTYGSS--FINFN--LPQFYQIVKVDGREQVIPFR 824
             +       +++ +  F+ S  DR T  +     +F      FY++ +   +  V   +
Sbjct: 790 RFYRNSQAVFVLKTLHYFFRSVIDRQTQLNQQLLHDFGIFPIHFYELKRDSRQCYVSEPK 849

Query: 825 TKSIGNMPPANQDHDTPL 842
             +  ++ P   +     
Sbjct: 850 RVANESVVPVELELRAIG 867


>UniRef50_Q1N416 Adenylate cyclase n=1 Tax=Bermanella marisrubri RepID=Q1N416_9GAMM
          Length = 952

 Score =  897 bits (2319), Expect = 0.0,   Method: Composition-based stats.
 Identities = 246/833 (29%), Positives = 414/833 (49%), Gaps = 22/833 (2%)

Query: 6   ETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYT 65
           + + +RL A NQ R +R L+A+    +    +LP L H +   +PG++  + P G+  Y 
Sbjct: 16  QQVVKRLLAYNQYRYERTLSALTERQKHFLDVLPLLYHVNSDKLPGFVGPDCPCGMARYQ 75

Query: 66  PDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWL 125
           P +      + L +  G   Q    G   I  ++ MGS  S+G S  SD DIW+CH S L
Sbjct: 76  PSKDVLRSASTLSM--GFQYQQRRMGHPAIRSLFIMGSCGSLGHSGGSDFDIWLCHDSNL 133

Query: 126 DSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDE 185
           D E   LLQ K   +E +A +LG+E+ FFL+D  RF   E   LG EDCGS QH LLLDE
Sbjct: 134 DEESMALLQNKALEIERYAETLGIELHFFLMDAKRFVRGERNDLGQEDCGSAQHQLLLDE 193

Query: 186 FYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFG 245
           FYRT++ LAG   +W +VP + E  YDD+V  LY Q   +  + +D GGL+ + A E+ G
Sbjct: 194 FYRTSILLAGCYPVWWLVPPEYEHLYDDFVYRLYQQRFASEEDVIDFGGLAEIPAGEFVG 253

Query: 246 ASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMM 305
           A +WQLYK+I SPYK++LK  L E+Y+  YPN   L+  +K RL D ++    LDPY ++
Sbjct: 254 AGMWQLYKAIGSPYKSILKLFLTESYASAYPNHEPLSISLKGRLFDDQVKLEKLDPYLLL 313

Query: 306 LERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARL 365
            +++ +YL   E+  RL+LVRRC Y K    + +      W+R +L  L+  WGW + +L
Sbjct: 314 YDKLEDYLLQREEGERLELVRRCLYFKANIPMGQSTRRKHWKRDLLRPLILNWGWSDGQL 373

Query: 366 AMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAA 425
           A LDNR++W +  V E    L++ ++ SY+ L  F R +      S +D+ +L  KLYA 
Sbjct: 374 AHLDNRSHWHVHIVMEERKHLVNELIHSYKFLSAFGREHEDETMMSAKDMTLLGHKLYAT 433

Query: 426 FEALPGKVTLVNPQISPDLSEPNLTFIYVPPG---RANRSGWYLYNRAPNIESIISHQPL 482
           F+  PGK+  +NP IS  + E  L+   +      R  +  W LY       +  +  P+
Sbjct: 434 FDRKPGKIDFINPGISKHIQEDKLSLHLLRQHVRRRIPQMNWSLYTGIARPGT--TDAPV 491

Query: 483 EYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLPKLQEMVADVSHHFPLRLPAPTPK 541
           + +  L +L+ W   N ++   T + + +G       +L+E++       PL   A  P 
Sbjct: 492 KRSANLIELLGWCHVNRIMDRGTNVVMYQGQQHGKDYELKEILNSF-QTMPLP-DAIEPD 549

Query: 542 ALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNS 601
              +P     LA+ VN+  DP + +  + +     + D   F   +  LV ++D L  NS
Sbjct: 550 FNATPV-PTFLALYVNVFVDPMSHYTRRGISKISNRTDSLGFSALKENLVLTIDQLQYNS 608

Query: 602 WNEVRTLHFNGEQSMIEALKTILGKMHQDAAPP-DSVEVFCYSQHLRGLIRTRVQQLVSE 660
           W EV +  + G+ +++  ++  L      +      ++V CY       I  RV++++ E
Sbjct: 609 WREVLSTRYEGQNALLRVIEDFLNAYPPGSKQDRPEMQVHCYCATRAKAIAARVKEVLEE 668

Query: 661 CIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSV 720
            ++L     R    R   L++  Q   +   +    +   E A   +  ++  + H   V
Sbjct: 669 -MQLCFYGNRIAERRRYVLQIGEQYHLIQMRQGRPMIDHFERAAHLFKKLASPQPHYSQV 727

Query: 721 QVETNHVK--LPAVVDGFASEGIIQFFFEE---TQDENGFNIYILDESNRVEVYHHCEGS 775
            +++  +K  +  ++   +  G++Q F+ +    Q +    IY++DE   +  +     +
Sbjct: 728 VLDSQALKGTILQMICKHSKPGVLQVFYVQEIGQQQQLTAQIYLIDERGSIIRWRTPMYN 787

Query: 776 KEELVRDVSRFYSSS---HDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRT 825
           +  L+  +  F        +R  YG+  +     ++Y+ V++  +E+ +  R 
Sbjct: 788 EAALINPIHHFLRQVEYRQNRHRYGNKTVRERPIEYYE-VQLPNKEESLRLRP 839


>UniRef50_A1TXX4 Adenylate cyclase n=2 Tax=Marinobacter RepID=A1TXX4_MARAV
          Length = 949

 Score =  897 bits (2318), Expect = 0.0,   Method: Composition-based stats.
 Identities = 252/839 (30%), Positives = 405/839 (48%), Gaps = 14/839 (1%)

Query: 15  INQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYL 74
           +NQ R  RA +A+    Q V  LLP + H +HP +PGYLDGN P G   YTP +      
Sbjct: 31  VNQQRWQRACSALTYRQQMVLELLPLVFHRNHPALPGYLDGNCPDGFSGYTPGQEVLDAA 90

Query: 75  NELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQ 134
                 R    +D    +  +  ++ MGS  ++G S +SDLD+W+CH+  L +   + L+
Sbjct: 91  RRY--ARSFHYRDKGTRKPDLDSLFLMGSPGTLGHSVASDLDVWLCHRQDLPASGIRCLE 148

Query: 135 RKCSLLENWAASLGVEVSFFLIDENRFRHNE-SGSLGGEDCGSTQHILLLDEFYRTAVRL 193
           RK   L  WA  LGVE+  F+     +R       + GE+CGS QH LLLDEFYRT++ L
Sbjct: 149 RKAEKLSEWAGGLGVELHVFVFSAADWRAGRQRVEVTGENCGSAQHFLLLDEFYRTSIHL 208

Query: 194 AGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYK 253
           AG+  LW ++P D E  YD     L     +   +++D G +  +   E  GA +WQLYK
Sbjct: 209 AGQYPLWWLIPVDREADYDHCRRQLVECRFIQARDYIDFGAVPDIPPAELPGAGIWQLYK 268

Query: 254 SIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYL 313
            ID+P+KA+LK LL+E Y+ +   P LL+   KQ +H+G I +  LDPY ++ +R+ ++L
Sbjct: 269 GIDAPWKAILKLLLIECYATDRERP-LLSASFKQAVHNGVISADALDPYVLLYQRLEQWL 327

Query: 314 TAIEDFTRLDLVRRCFYLKVCEKLSRERAC-VGWRRAVLSQLVSEWGWDEARLAMLDNRA 372
            A +   RL+LVRR  YLK    LSR       WR  +L  LV  WGW    L  LD+R 
Sbjct: 328 LARDGADRLELVRRSLYLKSGLPLSRAGMVGDPWRVELLRSLVEGWGWSSEDLGRLDDRQ 387

Query: 373 NWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGK 432
            W  ++V      ++  +  SYR L R AR  +   S S  DI +L RKLYAAF+   GK
Sbjct: 388 RWCAEEVMGLRRRVVAELTHSYRLLARLAREQDAQASISANDINLLGRKLYAAFQRKAGK 447

Query: 433 VTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLV 492
           V L+NP + P L+E NL+F +     A   GW LY    +         +     L +L+
Sbjct: 448 VELINPGLVPSLAEENLSFHHRSEQGAAGDGWLLYRDLEDPSDAFWQPVIRRAGNLAELL 507

Query: 493 AWAWFNGLLTSRTRLYIK-GNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRH 551
            W + NGLL+  TRL ++ G  +  + +L+E++  ++   P+ +P    +AL        
Sbjct: 508 VWCYCNGLLSRSTRLNVRAGQSVASVSELKEILDVLAGFLPVPMPPAPRQALSRAVRPLR 567

Query: 552 LAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFN 611
             +++N+  DP A    + +H    + D   F   ++ LV ++D +  NSW+EV   H+ 
Sbjct: 568 NLLLLNVAVDPQAHLTERGLHKLSARNDSLGFSGARDNLVVTIDQITLNSWHEVSLQHYA 627

Query: 612 GEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQ 671
              ++I+ LK +L ++  + A    + V   S+     I  RV +L ++ +    +    
Sbjct: 628 AGDTLIQCLKNVLAQVAINPAELPDIRVMAPSRGHGQAIARRVSELFADVLRQFFAGGTG 687

Query: 672 ETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPA 731
                  + +  + + L F         L++      A+   +   L V  +   ++   
Sbjct: 688 PHPLRYIIEMDQRYFLLQFNGQEPGFVALDSRAALMDALFQPQDSFLPVVPDRYALQDAP 747

Query: 732 V---VDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYS 788
           +   V   +  G IQ F++   D+    ++++DE   +         +  L+  + RF  
Sbjct: 748 LLKAVCEASEAGNIQVFWQLQGDQG--QLWVVDEYGSLWHRQLKAQQRRHLLAPLLRFLD 805

Query: 789 SSHDRF--TYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQ 845
           S  +R       +       + Y++V+ DGR    P R + +  MP +  +     +QQ
Sbjct: 806 SVIERRQLRQADNLEPVAGIRCYELVRRDGRWLADP-RPELVAGMPLSGLEVQAVGVQQ 863


>UniRef50_P40134 Adenylate cyclase n=25 Tax=Pasteurellaceae RepID=CYAA_HAEIN
          Length = 843

 Score =  894 bits (2311), Expect = 0.0,   Method: Composition-based stats.
 Identities = 355/850 (41%), Positives = 504/850 (59%), Gaps = 27/850 (3%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           M   +   KQ + A++Q R +RAL   G AFQ V +++P LLH +HP +PGY+    P G
Sbjct: 1   MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIVPLLLHLNHPQLPGYVIHA-PSG 59

Query: 61  ICLYTPDETQRHYL-NELELYRGMSVQDPPKGE-------LPITGVYTMGSTSSVGQSCS 112
           I  +   + Q+ +L NE  ++         K          PI GVY MGS  S+ Q+ S
Sbjct: 60  IASFLASDYQKKWLTNEYGIHYADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSS 119

Query: 113 SDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFR-HNESGSLGG 171
           SDLD W+C +  L  +E  LL +K   +  WA    VE++F+L+D+ RFR  + +  L  
Sbjct: 120 SDLDTWICVRDGLSLDEYTLLTQKAKRISEWAMQFNVEINFYLMDQQRFRNEHYADPLTI 179

Query: 172 EDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLD 231
           E+ GS Q++LLLDEFYR+AVRLAGK +LW  +  + E+ Y+  V  L  +G + PN+W+D
Sbjct: 180 ENSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVD 239

Query: 232 LGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHD 291
            GGL   SA EYFGASLW LYK IDSPYK+VLK LLLEAYS EYPN  L+A+  K+ L  
Sbjct: 240 FGGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLA 299

Query: 292 GEIVSFGL-DPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAV 350
           G        DPY  +L +VT+YLTA+ +F RLD V RCFY+K  E  +R +A   WR   
Sbjct: 300 GNTNPDHHFDPYIAILAKVTQYLTALSEFKRLDFVHRCFYVKATEDFARYQAN-NWRIRY 358

Query: 351 LSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSA 410
           +  L  EWGW    +  L+ R  WKI  V+E H+ ++  +M SYRNL+ FAR++++  S 
Sbjct: 359 MEILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLMLSYRNLVEFARKHHIHSSV 418

Query: 411 SPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRA 470
            PQDI +L+RKLY AFE LPGKV+L+N QIS +LSE +LTF+ V   +  + GWYL N+ 
Sbjct: 419 VPQDINILSRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQP 478

Query: 471 PNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHH 530
            +       + +EY   LNKLV+WA+FN LLT +T L I     V L  LQ  V ++   
Sbjct: 479 IHHIMFSKERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKN-VTLSTLQRFVTNLRQS 537

Query: 531 FPLRLPAPTPK-ALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNC 589
           FP  +        L + CEIR L I +NL  DPT+     +     R  D+FSFG  +  
Sbjct: 538 FPSTIAKQPKNSDLLNQCEIRSLFIAINLTTDPTSKVEEVLTGISSR--DLFSFGSLEQS 595

Query: 590 LVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGL 649
           LVGS+D  YRN WNE+RTLHF G+ +++ ALK +  K+++    PDS++V+CYS+  R  
Sbjct: 596 LVGSIDFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRPDSIQVYCYSERYRQD 655

Query: 650 IRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENA---IEF 706
           +R  V  LV+ C+ +++    Q+  +   LRV+G+ W LFFE   +S+Q++ N     E 
Sbjct: 656 LRQLVMGLVNRCVSIQVGDI-QQPCQTSRLRVAGKNWQLFFEDRGISLQEIGNESVCNEA 714

Query: 707 YGAISHNKLHGLSVQ-VETNHV--KLPAVVDGFASEGIIQFFFEETQDENGFNIYILDES 763
             A+  +++    ++  ETN    + P  +D FASEG +QFFFE+  D + FN+YILDES
Sbjct: 715 ESAVDFDEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSD-HSFNVYILDES 773

Query: 764 NRVEVYHHCEGSKEELVRDVSRFYS---SSHDRFTYGSSFINFNLPQFYQIVKVDGREQV 820
           N +E+Y HC+G K+E VR++++ Y       D+  Y     NFN PQFYQ+        +
Sbjct: 774 NHLEIYRHCDGEKDEKVREINQLYQNAKQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISI 833

Query: 821 IPFRTKSIGN 830
           +PF+ + +  
Sbjct: 834 VPFKFRQMNK 843


>UniRef50_A4BK19 Adenylate cyclase, class I n=1 Tax=Reinekea blandensis MED297
           RepID=A4BK19_9GAMM
          Length = 985

 Score =  893 bits (2308), Expect = 0.0,   Method: Composition-based stats.
 Identities = 244/836 (29%), Positives = 400/836 (47%), Gaps = 16/836 (1%)

Query: 4   YIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL-DGNVPKGIC 62
           +++   +R   +NQ R+ R    + P  QQ + LLP L H +H  +PGY    +VP GI 
Sbjct: 55  HVQHATERFMTVNQGRLARVREGLQPKQQQCFDLLPLLFHINHESLPGYSSRDDVPFGIS 114

Query: 63  LYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQ 122
            Y P +T         + RG   +     +  ++ +Y MGS+ S+GQS SSDLDIWVC+ 
Sbjct: 115 NYHPSDTVIRLA--QSITRGQVGKRVSLTKPALSALYLMGSSGSIGQSTSSDLDIWVCYN 172

Query: 123 SWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILL 182
           S L+  +   LQ K   +  WA+   +EV FFL+D +RF   E  SL GE+CGSTQH+LL
Sbjct: 173 SELNDRDIDRLQTKAEQISVWASGFNLEVHFFLMDAHRFSGGEQQSLTGENCGSTQHVLL 232

Query: 183 LDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEE 242
           LDEFYRT   LAG    W +VP   E  Y   + T+   G +      D G +++L A E
Sbjct: 233 LDEFYRTVQVLAGNIPAWWLVPTAFESEYRSALDTMAYDGYVNDANTTDFGPIATLPAGE 292

Query: 243 YFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPY 302
           + GA +WQ+YK+IDSPYK+VLK +LLE Y+ EYP    LA   K  ++  ++    LDPY
Sbjct: 293 FIGAGMWQIYKAIDSPYKSVLKLILLEIYAREYPAIESLAHQYKSDIYRMKLSLDDLDPY 352

Query: 303 CMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDE 362
            M+  R+  YLT  ++  RL L+RRCFY KV   LS+      WRR ++  L+  WGW +
Sbjct: 353 VMLYRRIESYLTERDEMERLALLRRCFYFKVGLNLSKPTRTYNWRRELMDYLLDSWGWTK 412

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
           + +A LDN   W I++V      L++ +  SYR L  FA  ++ +   S +D+ +L+RKL
Sbjct: 413 STIAHLDNFRAWTIEEVLSERRLLINELTHSYRFLTEFASEHHSTHVMSQRDLLILSRKL 472

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSG-WYLYNRAPNIESIISHQP 481
           +AAF+  PGK+  +   +  DLS   +        +      W  YNR  + +   S  P
Sbjct: 473 HAAFDRRPGKIDFIRIGLDVDLSHEKIRLYERESKQEPGVFLWAAYNRPLDADP--SPSP 530

Query: 482 LEYNRYLNKLVAWAWFNGLLTSRTRLYIKG-NGIVDLPKLQEMVADVSHHFPLRLPAPTP 540
           L+Y++ L + + W+  NGL+++   + I      +   +++ ++A +    P  LP    
Sbjct: 531 LKYSKGLLETLLWSHLNGLISAHLHIPIYPMQQAITEFEIRMLLASMRQILPTPLPKIDS 590

Query: 541 KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRN 600
            + Y P  +  +   +N+  DP      + +     + +   F   +  LV S+D++  N
Sbjct: 591 NSFYHPAILTKVVCFINVGRDPLHYLSARGLQKISARSNSLDFSALRENLVLSIDMVLVN 650

Query: 601 SWNEVRTLHFNGEQSMIEALKTILGKM-HQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVS 659
           +W EV    F  + +M +ALK+++ ++  Q  +    +E  C++Q     I  RV+ L  
Sbjct: 651 TWGEVVVERFADQDAMTKALKSLINRVNKQTRSGLPIIETVCHNQTRPQAIAKRVKDLFE 710

Query: 660 ECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLS 719
           + +    S    +  RF    +S             + Q L +  E    + H +     
Sbjct: 711 DALSALCSPMHPKNTRF-VFNLSDNCILFQHINRVTNFQTLSDVTELEQHLGHEQAEYSP 769

Query: 720 VQVETNHVKLPAVVDGF---ASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSK 776
           V  +    +   ++       S   +   FE    +    +Y++DE   +  +     + 
Sbjct: 770 VVFDRVFQQDQPLMSQLYQTHSANTVNVAFELQTTQAT--LYLIDEQGSLMRFVQPLHNV 827

Query: 777 EELVRDVSRFYSSSHDRFTYGSS--FINFNLPQFYQIVKVDGREQVIPFRTKSIGN 830
             L+  + RF   +  R    +    +     Q +QIV+     ++   +   + N
Sbjct: 828 ATLLSPLLRFLKVTEHRQRSNTDVQLMPQRTIQCHQIVRQKNGLELKRIKLGGLVN 883


>UniRef50_Q1I310 Adenylate cyclase n=23 Tax=Pseudomonas RepID=Q1I310_PSEE4
          Length = 954

 Score =  875 bits (2260), Expect = 0.0,   Method: Composition-based stats.
 Identities = 285/855 (33%), Positives = 432/855 (50%), Gaps = 24/855 (2%)

Query: 3   LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGIC 62
             +  L+ R   INQ R+ RAL  +    QQV +LLP   H +HPL+PGY+ GN P G+ 
Sbjct: 18  KELSRLRARFLKINQGRLARALEGLSTRQQQVLTLLPLFFHVNHPLLPGYVSGNTPAGVS 77

Query: 63  LYTPDETQRHYLNELELYRGMSVQDPPKGEL-PITGVYTMGSTSSVGQSCSSDLDIWVCH 121
            + PD           L R  + +        PI G++ MGS  ++ Q+  SD+D+WVCH
Sbjct: 78  GFEPDTELL--AEAQRLTRSFTYKARHGNPPQPIHGLFLMGSLGTLAQAEQSDMDLWVCH 135

Query: 122 QSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGS-LGGEDCGSTQHI 180
              LD +    L+RKC LLE+WAA+ G E   FLI+   F   E  S L  +DCG+TQH 
Sbjct: 136 APGLDEQALAELRRKCQLLEDWAATQGAEAHLFLIEPQGFVQGERDSRLSSDDCGTTQHY 195

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLLDEFYRTA+ LAG+  LW +VP  +E +Y DY  TL ++  +   + LDLG L+ + A
Sbjct: 196 LLLDEFYRTALWLAGRTPLWWLVPVYQEHNYRDYTQTLLSKRFIRVTDALDLGHLAHIPA 255

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLD 300
            EY GA LWQLYK IDSPYK++LK LL E Y+ E+P+ R L+ D KQ +    +    LD
Sbjct: 256 GEYVGAGLWQLYKGIDSPYKSLLKLLLTETYASEHPHVRCLSLDFKQAVFANRLDLDELD 315

Query: 301 PYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS--RERACVGWRRAVLSQLVSEW 358
           PY M+  R+ +YL    +  RL+LVRR  YLKV +KL        VGW+R +L++L  EW
Sbjct: 316 PYVMVYRRIEQYLLRRGETARLELVRRSLYLKVNKKLGGLGRSRNVGWQRQLLARLAEEW 375

Query: 359 GWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVL 418
           GWDE +LA+LD+R+ WK+ QV     EL+  +  SYR L +FAR  N +  A  +D+ VL
Sbjct: 376 GWDERQLALLDSRSQWKVRQVAVERRELVAELNHSYRFLTQFAREQNANSRADQRDLNVL 435

Query: 419 TRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRS-GWYLYNRAPNIESII 477
            R+LYAAFE   GK+ ++NP I+PDL+E  LT +  P  +   +  W LYN    +    
Sbjct: 436 GRRLYAAFERRAGKIEMINPGIAPDLAEDTLTLVQSPNRKEPGTHHWGLYNGNLGVHEWE 495

Query: 478 SHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIK-GNGIVDLPKLQEMVADVSHHFPLRLP 536
              P++  R L +L+ WA  NG++ S TRL +  G   +   +L  ++  +    PL L 
Sbjct: 496 HFSPIKRCRELLELLTWAHRNGVIDSSTRLALHPGASDLSEFELFNLIGSLQQSIPLPLE 555

Query: 537 APTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDL 596
             +   L  P     + ++VN+  DP    R+  +     + D  S+   +  LV ++D 
Sbjct: 556 TVSEVRLLQPSVADEILLLVNVGVDPLRHHRDLNILMTTERTDSLSYAGVRENLVLTLDQ 615

Query: 597 LYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQ 656
           +  NSWNEV    ++GE ++   L+  L  +   +  P  V V CY  +    I  RV++
Sbjct: 616 ITLNSWNEVLVQRYDGEHALARCLRDFLNSLGHRSHRP-RVRVCCYCHNRAQAISQRVEE 674

Query: 657 LVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLH 716
           +  + ++L L    Q       L+V+  T  L  +   V++  L         +   +  
Sbjct: 675 IF-DTVQLLLD---QNLNHRYLLQVARHTHVLELQPGQVTLATLVEHDALLATLGEERNS 730

Query: 717 GLSVQVETNHVK---LPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCE 773
              + ++ N ++   LP V+     +  IQ F+     +   ++Y+LDE N +       
Sbjct: 731 YSPLHLDANALQDYDLPLVLSQGQPQ-CIQVFYRLL--DGWADLYVLDEYNALWQQRLPL 787

Query: 774 GSKEELVRDVSRFYSSSHDRFTYGSSFINFNL----PQFYQIVK-VDGREQVIPFRTKSI 828
             +  L+  + RF  S   R        +         +YQ++    G+ + +  R   +
Sbjct: 788 QDELHLLLPLQRFLQSMVMRRDAQLPLDSLQQASLDILYYQLLPSGVGKARGLEPRPAPV 847

Query: 829 GNMPPANQDHDTPLL 843
                   +    L 
Sbjct: 848 DGRDRPYYEVQAILQ 862


>UniRef50_B3H1T6 Adenylate cyclase n=12 Tax=Pasteurellaceae RepID=B3H1T6_ACTP7
          Length = 842

 Score =  850 bits (2195), Expect = 0.0,   Method: Composition-based stats.
 Identities = 337/825 (40%), Positives = 508/825 (61%), Gaps = 25/825 (3%)

Query: 10  QRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDET 69
            R+DA++  R  RALAA  P F+QV+SLLP L+H + P +P Y+  N P GI  +   E 
Sbjct: 35  SRVDALDHFRTQRALAANSPQFEQVFSLLPLLIHTNLPELPAYIK-NAPSGIAAFELSEY 93

Query: 70  QRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEE 129
           Q +YL+EL L   +++++     +   G+Y+MGST ++ Q+  SD+D+W+C+   L++ E
Sbjct: 94  QANYLSELSLS-HLAIRNSA-DLVAFDGLYSMGSTGTITQTSLSDIDLWLCYSDRLNALE 151

Query: 130 RQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHN-ESGSLGGEDCGSTQHILLLDEFYR 188
            QL+++K   ++ WA  LGV+VSF+L++   F+ +     +  E  GS QH  LLDEFYR
Sbjct: 152 YQLVEQKLDKIKQWAKRLGVDVSFYLMNPAHFKAHLYHSDVNEEHSGSAQHYFLLDEFYR 211

Query: 189 TAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASL 248
           +A+RLAGKR+LW  +P       D       +     P EW+D G  SSLS  E+FGASL
Sbjct: 212 SAIRLAGKRLLWLHLP-------DGLYQQYLSSAEFNPAEWIDFGDFSSLSTGEFFGASL 264

Query: 249 WQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLER 308
           WQLYK I+ PYK+ +K LLLE+Y+  YPN  L++K  KQ+L   + V +  DPY  MLE+
Sbjct: 265 WQLYKGIEYPYKSAIKILLLESYADTYPNTNLISKQFKQKLLAVQTVEYHFDPYLAMLEQ 324

Query: 309 VTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLAML 368
           VT+YL+  ++  RL  +R CFY+K  E  SRE     WR   L +L+  W W+   L +L
Sbjct: 325 VTDYLSKRKEMLRLSRLRMCFYVKASEGESRE----TWRTQALRELIEGWNWNLQELNLL 380

Query: 369 DNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEA 428
           DNR NWKI Q       +++ ++QSYRNLI+FAR+ ++  S    DI +L RKLY+ FE 
Sbjct: 381 DNRQNWKIKQAVTHQQIIVEQLLQSYRNLIQFARKFHIDPSILASDIDILMRKLYSVFEM 440

Query: 429 LPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYL 488
            PGKV L+NPQIS +L+E  +TFI V  G A ++GWY+ N+AP      + + +   + L
Sbjct: 441 APGKVPLINPQISENLAESAVTFIEVREGSAMQAGWYMINQAPRSPYDPALRYVRQAKNL 500

Query: 489 NKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCE 548
            KLVAW +FNG++TS T+L++     +DL +L++ + D+   FP++ P      L  P E
Sbjct: 501 TKLVAWGYFNGVITSNTQLHLVSRS-LDLSRLRQFITDLRLSFPVKAPEMIDDDLLHPNE 559

Query: 549 IRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTL 608
           IR L + +NL  DPT     +      +  D+F+FG  Q  LVGSV ++YRN WNE+RT 
Sbjct: 560 IRSLILAINLVKDPTQKL--EPTRRAVQPSDLFNFGSAQQSLVGSVSIIYRNLWNEIRTQ 617

Query: 609 HFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSS 668
           HF G+ ++++ALK I  K+++ +A P SV VFCYS+HLR  +R  + +LV +CI ++  +
Sbjct: 618 HFEGDDAILKALKLISNKIYRSSASPQSVNVFCYSRHLRSELRDFIAELVHKCITIQTGT 677

Query: 669 TRQETGRFKALRVSGQTWGLFFERLNVSVQKL-ENAIEFYGAISHNKLHGLSVQVETNHV 727
             Q+      L+V+G+ W   F +  V +Q L E A+EF   I++ +     +  ++N V
Sbjct: 678 ISQKQPL-STLKVAGKMWQFVFGKQKVEIQPLNEQAVEFNQEIANLQDE-AGMHAKSNCV 735

Query: 728 KLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFY 787
             P  +D FASEG +QFFFE+  DE  FN+YILDE N +EV H C  SKEE V++++R +
Sbjct: 736 F-PKEIDEFASEGFLQFFFEDNADE-SFNVYILDEKNTLEVCHDCFCSKEEKVKEINRIH 793

Query: 788 SSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMP 832
           ++ + +    +S  +FN PQFYQ++ ++G+ +++PF++K      
Sbjct: 794 AAENSK--ENASLESFNFPQFYQLISLNGKTRIVPFQSKQHRQYL 836


>UniRef50_A1SAP9 Adenylate cyclase n=18 Tax=Shewanella RepID=A1SAP9_SHEAM
          Length = 809

 Score =  780 bits (2015), Expect = 0.0,   Method: Composition-based stats.
 Identities = 265/818 (32%), Positives = 405/818 (49%), Gaps = 44/818 (5%)

Query: 13  DAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRH 72
           D +N++R+ RALA + P  + +   +P LLH+H P +PGY     P G+  + P E    
Sbjct: 16  DRLNKVRLARALALLSPLKRHLLHAIPLLLHFHGPRIPGYNGHATPCGLAGFEPQEPHLE 75

Query: 73  YLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQL 132
               L L       D P     I G+Y MGST S GQ+  SD+D+WV H+  L +++ Q 
Sbjct: 76  AARVLSLGLPSLRADWP---YAIEGIYAMGSTGSFGQNPFSDVDVWVIHEPNLSADDIQA 132

Query: 133 LQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGS------LGGEDCGSTQHILLLDEF 186
           L  K  LL  W A    EV+F+L+   +FR ++S S      LG E  GS QH LLL+EF
Sbjct: 133 LADKLVLLHQWFAGFEFEVNFYLVHPFQFRADKSYSGNGRVRLGVEHSGSAQHWLLLEEF 192

Query: 187 YRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGA 246
           YRT + L GK + W                          ++ L LG + SL A EYF A
Sbjct: 193 YRTQICLGGKPLYWWPDA-------------------RPSSDGLWLGDVQSLPASEYFSA 233

Query: 247 SLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMML 306
           SLWQLYK +  P+KA+LK LLLEAY+W YPN   L+  +      G+  S   DPY ++ 
Sbjct: 234 SLWQLYKGLVKPHKALLKVLLLEAYAWRYPNTEQLSTRVWLHTTKGDF-STANDPYFLLY 292

Query: 307 ERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLA 366
           E + EYL AIED  RL++VRRCFYLK   +LS  +    WR   +  LVS W W +A + 
Sbjct: 293 EAIEEYLLAIEDHRRLEIVRRCFYLKCAVRLSHPQQPKDWRYLKMQLLVSAWEWPDALIQ 352

Query: 367 MLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAF 426
            LD+  +W   Q++  + +L + M+ SY+ L+RFA  + ++     +D+G+LTRKL+  F
Sbjct: 353 TLDDCEDWHTGQLQWFNAQLNELMLVSYQKLLRFAANHGVNEGLRVEDLGMLTRKLHTCF 412

Query: 427 EALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNR 486
                 V+ +NP  S  L EP LT I       +    YLY + P   ++     +    
Sbjct: 413 NEDKHLVSKLNPLWSSRLQEPVLTVITSQSDGTH----YLYRQEPQASALKGEAAVYVAD 468

Query: 487 YLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSP 546
            L  L+ WA  N +   +T+ +  G   +   +L      +           + + L  P
Sbjct: 469 NLASLLLWACINQVCDDQTQWFSYGERRLG-ARLAATDKRLREAIKDTELKVSKQDLCQP 527

Query: 547 CEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVR 606
              R L ++VNLE+DPT  +  Q V  D    ++FS G  Q  ++GS+D+L  NSW E  
Sbjct: 528 WHYRKLVLVVNLEHDPTPDWPGQEVLVDIMNANLFSLGRKQLNMLGSLDVLSFNSWGEWH 587

Query: 607 TLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRL 666
             HF GEQ++++A+  +   + + A   D   + C S  L   +   V  L+ +  +L  
Sbjct: 588 AHHFEGEQALLKAMTFLAPGIRRAAGRLDLRTLGC-SARLTFQLELAVHSLLKQVAKLSC 646

Query: 667 SSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQ--VET 724
            +    +   + LR+  + +GLFF  L V+ + L +A   Y  +S   L  +      + 
Sbjct: 647 QA-SASSTLVQPLRIGNRNYGLFFNTLGVAYEDLADAPSIYKQMSRGHLLSIPRPELGDD 705

Query: 725 NHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVS 784
               +P ++  +A+E +IQ+F      E G +++IL+  N +  Y     + E LV  VS
Sbjct: 706 PFASVPELIQDYATEDVIQYFLRPR--EEGIDVFILNHKNEISHYVQHGTTVEALVSKVS 763

Query: 785 RFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIP 822
           + ++       +G     FNLPQF+Q+V++ G  +  P
Sbjct: 764 QQHAFEGLYEMHG----RFNLPQFFQLVRMQGELKAQP 797


>UniRef50_Q088L2 Adenylate cyclase n=1 Tax=Shewanella frigidimarina NCIMB 400
           RepID=Q088L2_SHEFN
          Length = 819

 Score =  768 bits (1983), Expect = 0.0,   Method: Composition-based stats.
 Identities = 241/834 (28%), Positives = 408/834 (48%), Gaps = 54/834 (6%)

Query: 9   KQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDE 68
           K   + +N +R+ R L  +  +   ++ L+P L+H++   +PG +D + P GI  +T  +
Sbjct: 10  KDLAEKLNGIRLARVLNVLPESQLHLFHLIPFLIHHNQINVPGIIDPDTPCGIHGFTLSD 69

Query: 69  TQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSE 128
                 + L L     +Q     +    G+Y MGST+S GQ+  SD+DIW+ + S L  +
Sbjct: 70  AIVSACDALSLSIPEMIQ---PSDCVFEGIYAMGSTASFGQNPQSDVDIWLVYNSKLTDD 126

Query: 129 ERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRH----NESGSLGGEDCGSTQHILLLD 184
           + +L++ K  L+ +W A    EV+F+L+   +FR     +    +G E  GS+QH LLL+
Sbjct: 127 QLKLIEYKNKLISDWFAGFEFEVNFYLVHPMQFRECSAFDNCQPVGLEHSGSSQHWLLLE 186

Query: 185 EFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYF 244
           EFYR+ +RLAGK + W      +   +D  +              L LG ++SL A EYF
Sbjct: 187 EFYRSHIRLAGKVVAWWPDANSQNTEFDASL--------------LYLGDINSLPAAEYF 232

Query: 245 GASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCM 304
           GASLWQLYK ++ P+KA+LK LLLE Y+ EYP+  L+ + I Q     +      D Y +
Sbjct: 233 GASLWQLYKGLNKPHKALLKVLLLETYASEYPSTTLITQQIWQYCEQQDFSVD-NDAYLL 291

Query: 305 MLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLS--RERACVGWRRAVLSQLVSEWGWDE 362
           + +R+  YL A  D  RL++VRRCFYLK    LS     +   WR   +  LV +W W  
Sbjct: 292 LYQRIETYLIAQGDDNRLEIVRRCFYLKSGVTLSCLSPNSAADWRVEKIQNLVKQWAWSH 351

Query: 363 ARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKL 422
             +A LDN   W   Q++  + +L + ++ SY+NL++FA +  LS     +++G+L RKL
Sbjct: 352 ELVATLDNSPYWHAGQLKWFNQQLSELLLVSYKNLLQFASKQTLSERMRVEELGLLARKL 411

Query: 423 YAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRA---PNIESIISH 479
           +  F      +  +N   S   +E +LT  +        S +YLY +A    +    + +
Sbjct: 412 HTYFSEDTHLLQPLNRLWSLSTAEKSLTIFHCRQA----SRFYLYRQAYLDKDPSQAVDN 467

Query: 480 QP--------LEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHF 531
            P        +     +  LVAW+  NGL T+ T+ +  G G     KL  +   +    
Sbjct: 468 DPAHEFDDHSIHEADNICNLVAWSVLNGLATADTQWFQVGRGKRRTDKLSYLTRKL---I 524

Query: 532 PLRLPAPT--PKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNC 589
           P+    PT   + L  P   + + +I N++ DPT     Q +  +    ++ SFG+ +  
Sbjct: 525 PIMHNVPTVYKRDLCEPWCYQKIVLITNMDRDPTTQLSEQELILEHVNANILSFGQTKIS 584

Query: 590 LVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGL 649
           +V SV ++  NSW E ++  FNG+ +++EA+  I+  + +     D   + C S  L+  
Sbjct: 585 MVSSVAIVCLNSWGEWQSHRFNGKTALLEAISFIILGLKRSNEQVDLSIISC-SAKLKQP 643

Query: 650 IRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGA 709
           I  +++ L+  C  L +    Q       + +  Q + + F  L +  +K+ + I   G 
Sbjct: 644 IFNQLKTLLLRCYGL-MKKVNQTNTLMHPITIGEQHYSMHFNSLGMMYRKV-DLITGTGN 701

Query: 710 ISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVY 769
            + + L    +  E  ++  P+V+  F   G  Q+F  E       +++I D++N++E  
Sbjct: 702 FNSSVLPYADL-AEDPYLNSPSVIQKFIVMGAKQYFLRERH--QTLDVFIADDNNQLEHL 758

Query: 770 HHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPF 823
            +   S  + V   S  Y     +         FN+PQF+Q+V ++G+  VIPF
Sbjct: 759 QYQHTSINDFVAKESHLYVFDEQKQRS----PVFNMPQFFQLVDIEGKLTVIPF 808


>UniRef50_B3PH57 Adenylate cyclase, class I n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PH57_CELJU
          Length = 651

 Score =  711 bits (1834), Expect = 0.0,   Method: Composition-based stats.
 Identities = 229/630 (36%), Positives = 331/630 (52%), Gaps = 19/630 (3%)

Query: 3   LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGIC 62
             +  L++R  ++N+ RV R L  +    QQ   LLP L H +HP++PGY+ G  P G+ 
Sbjct: 18  KQLTLLRRRFLSLNEQRVARTLTNLSERQQQFMQLLPLLFHVNHPMLPGYISGATPAGVY 77

Query: 63  LYTPDETQRHYLNELELYRGMSV-QDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCH 121
            Y PD+          L R  +  +D  +    I  ++ MGS  S+  +  SD+DIWVCH
Sbjct: 78  AYQPDKDSLRLAR--ILARSFTYTRDLVETTPGIDALFLMGSVGSIAHTAGSDMDIWVCH 135

Query: 122 QSWLDSEERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
              LD    Q L+RKC ++ +WAAS + +EV FFL+    F+  +  S+  E  GS QH 
Sbjct: 136 NPTLDLPALQELERKCQVITHWAASQIHLEVHFFLMTGEHFQTGKCSSMSSEASGSAQHY 195

Query: 181 LLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA 240
           LLLDEFYRTA+ LAGK  LW  VP   E  Y  Y  TL  +  +   E +D GGL  + A
Sbjct: 196 LLLDEFYRTALWLAGKVPLWWFVPVTREADYRRYSETLLHKRFIKAAEVIDFGGLPFIPA 255

Query: 241 EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYS----WEYPNPRLLAKDIKQRLHDGEIVS 296
            E+ GA +WQLYK+I SPYK+VLK LLLE Y+     +      LA  +K+ L++ E   
Sbjct: 256 NEFIGAGIWQLYKAIASPYKSVLKLLLLEVYASGDTAQDTATEPLALSLKRALYEREPDV 315

Query: 297 FGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERA--CVGWRRAVLSQL 354
             LDPY M+ ER+  YL A     RL+LVRRC Y K+ + LSR+ A     W+R +L  L
Sbjct: 316 DRLDPYVMIYERIERYLCARHQDARLELVRRCLYFKINKPLSRKNARTKKSWQRVLLEDL 375

Query: 355 VSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQD 414
              WGW+  +L MLDNRA WK   V      L++ +  SYR L    ++  L+ + S  +
Sbjct: 376 THAWGWNSHQLHMLDNRAYWKSPHVIAERALLVNELNHSYRLLAELNKQLGLNAAISTDE 435

Query: 415 IGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIE 474
           + VL RKL+AAFE   GKV  +NP IS +LSEP L F  V         W L   +    
Sbjct: 436 LQVLGRKLHAAFERKAGKVEYINPGISRNLSEPALCF--VQDKSVAGESWQLVRGSQQDL 493

Query: 475 SI--ISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI--KGNGIVDLPKLQEMVADVSHH 530
           ++  ++ +P+   R L +L+ W+  NGLL   TR+ +  K   I  L K Q+++  +   
Sbjct: 494 TLRSVAVEPVRRARSLVELLVWSQVNGLLVPGTRVDLISKDYQITALQK-QQLLQAILQW 552

Query: 531 FPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCL 590
            P     P  +A  S   +  + ++ NL  +P A    + +     + D   F   +  L
Sbjct: 553 LPEPH-QPEHQAFTSAARVEKVLMLFNLGVEPQAELHKRGMQMLSAQSDPLGFSGFRANL 611

Query: 591 VGSVDLLYRNSWNEVRTLHFNGEQSMIEAL 620
           V SVD++  NSW E+   H+  + +++ AL
Sbjct: 612 VLSVDIVQLNSWGELVARHY-PQDALVNAL 640


>UniRef50_C8R2N0 Putative adenylate cyclase n=1 Tax=Desulfurivibrio alkaliphilus
           AHT2 RepID=C8R2N0_9DELT
          Length = 658

 Score =  595 bits (1535), Expect = e-168,   Method: Composition-based stats.
 Identities = 176/665 (26%), Positives = 308/665 (46%), Gaps = 49/665 (7%)

Query: 3   LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL-DGNVPKGI 61
           + ++    R    N+ R+ +++         +++ +P LLH +HP +PGYL +   P GI
Sbjct: 1   MGLKEKIARYHLYNEERIAKSVLLNPHKSNIIFAAVPYLLHVNHPDLPGYLNEPAAPCGI 60

Query: 62  CLYTPDETQRHYLNELELYRGMSVQDPPKGE--------LPITGVYTMGSTSSVGQSCSS 113
           C Y P       L     +R    Q  P+GE          I  + T+GS  ++ QS  S
Sbjct: 61  CNYNPATAFSFEL----FHRFFPGQSVPRGEEKMLPGNLCAIRSLMTIGSVGTIAQSEKS 116

Query: 114 DLDIWV-CHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGE 172
           D D WV  H+S L +   +LL  KC+ +  W A  GVE  FFL+D  + R N   S   E
Sbjct: 117 DCDYWVSVHRSQLGARGMELLAEKCAAIAAWTAKKGVETHFFLMDIEQTRENSFESAAME 176

Query: 173 DC-GSTQHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWL 230
           +  G++  ILL DE +RT V +AGK +LW  +P   EE+HY   V  L  +  + P++++
Sbjct: 177 ESAGTSLKILLKDELFRTHVLVAGKPLLWWFLPPGLEEKHYHGLVKRLVREHKINPDDYV 236

Query: 231 DLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYS-WEYPNPRLLAKDIKQRL 289
           DLG ++++  EE FGA LWQ+ K++DSP+K+V+K   LE     +  +P L +  IK+ +
Sbjct: 237 DLGCVATIPREEIFGACLWQMNKALDSPFKSVIKFAYLELLLQDQQSSPALFSDKIKRLV 296

Query: 290 --------HDGEIVSFGLDPYCMMLERVTEYL-TAIEDFTR--LDLVRRCFYLKVCEKL- 337
                       +    +DPY ++   +  +   A     R   DL+R C +LK  E + 
Sbjct: 297 TYPEKLPDQMEMLDPGEIDPYLLLAREIIAFYQQANNRPIRQWADLIRECLFLKTLEMVE 356

Query: 338 SRERACVGWR---RAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSY 394
           S++ A +G +   +A++ Q+  +W    A      N   W+   +    + +   + ++Y
Sbjct: 357 SQKHAKMGQKSHHKAIMEQM-EDWDILPANRQHFLNFRYWQYRDLLAFGSRVHGYLAETY 415

Query: 395 RNLIRFARRNNLSVS--ASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFI 452
           + L R  +  +  V    S +DI  L RKL+  +E  P K+  +       ++  ++T I
Sbjct: 416 KRLRRVFKEIDPEVGLTISERDIATLGRKLFTFYEKKPNKIDYIRSVSRYHMTMEDIT-I 474

Query: 453 YVPPGRANRSGWYLYNRAPNIESIISH--QPLEYNRYLNKLVAWAWFNGLLTSRTRLYIK 510
           ++      R  +Y +    +  +I       +  + +L +LV W   NG+L   T+L++ 
Sbjct: 475 HITK-YQERFFYYAFQGNLDHNTIREQVGAAIRRDDHLVRLVTWLMVNGMLARHTKLHLT 533

Query: 511 GNG-IVDLPKLQEMVADVSHHFP-LRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFR- 567
            N   +DL  +Q +   +   FP +      P+ L     I    ++VN   +P    + 
Sbjct: 534 KNFLPIDLADIQILAEKMLDTFPMVDFSKIPPQHLVEQENILRALVVVNFFKEPVKGNKT 593

Query: 568 ------NQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALK 621
                 ++  + ++   D  +  + +N L+  +   Y + WN    + F   Q  I A+K
Sbjct: 594 LASTIISENSYGEYFLHDYNTLAQLKNALLTLLTRHYVSRWNN-NLIVFIPNQDEISAIK 652

Query: 622 TILGK 626
            +L K
Sbjct: 653 NLLEK 657


>UniRef50_B4RT26 Adenylate cyclase, class I n=2 Tax=Alteromonas macleodii
           RepID=B4RT26_ALTMD
          Length = 661

 Score =  595 bits (1533), Expect = e-168,   Method: Composition-based stats.
 Identities = 169/680 (24%), Positives = 291/680 (42%), Gaps = 63/680 (9%)

Query: 11  RLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDG-----NVPKGICLYT 65
           R+   N+ R++RAL  M    + ++ +LP L+H +H  +PG++       +VP GI  Y+
Sbjct: 19  RVLRYNKARIERALTLMPEKHRPLFHVLPFLVHVNHESLPGFVAPLSTGESVPFGISNYS 78

Query: 66  -----PDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
                     R + +E  L+  +  Q  P+    +  +  MGS  ++ Q+  SD D WVC
Sbjct: 79  FRTDIEKALLRCFPSESHLFADIK-QIWPRQR-AVDALVLMGSVGTIAQTDDSDFDFWVC 136

Query: 121 -HQSWLDSEERQLLQRKCSLLENWA-ASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQ 178
                  S    LLQ+K + +E WA  + G+EV FFL + ++ + N+ G   GE  GS Q
Sbjct: 137 IDGKQFTSTALSLLQQKLTAIEKWADQTFGIEVHFFLSEIDKVKQNDFGVAEGESAGSAQ 196

Query: 179 HILLLDEFYRTAVRLAGKRILWNMVP-CDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSS 237
            + L  EFY T + +AGK   W + P    E+ Y     +L   G    + ++DLG L  
Sbjct: 197 ALFLKAEFYNTNIVVAGKAPFWWLTPEKTSEKQYQAIYNSLEKGGSPDLDWFMDLGHLEK 256

Query: 238 LSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSF 297
           L A E FGA++WQL K++DSP+K+VLK   LE Y       + L   +K+ +H G     
Sbjct: 257 LDASELFGAAIWQLGKAMDSPFKSVLKMAKLEVYLANIAEGQPLCNLLKKHVHRGAEAPG 316

Query: 298 G---LDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRE---RACVGWRRAVL 351
               +DPY +M + +  + +       + ++R C YLK    LS+         ++R ++
Sbjct: 317 HVADIDPYSLMFDELITHYSEHGQAEDIAVLRECLYLKCGCALSQPLMEDEKPNFKRRIM 376

Query: 352 SQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSAS 411
           +    +WGW+  +L+  DN+  W   +  +    +   +++ YR + +    +   +   
Sbjct: 377 ASYARQWGWNRKQLSHFDNQQEWNFSERVQLSRRIHRFLLKCYRRISKELSHHQQVMD-- 434

Query: 412 PQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNR-- 469
            +D+ VL R+L   +     K+  +       L    +T I +   +     W  Y    
Sbjct: 435 EKDMTVLGRRLSTYYAKKADKIEFLRRAFDESLYCEKVT-IAMRQLKNGEEVWSAYAGDL 493

Query: 470 APNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGN-GIVDLPKLQEMVADVS 528
                 I   Q +        L+ W   + ++ + +++Y+  N G V    L +++  + 
Sbjct: 494 LSKSGIIDESQKITQASSAIALMVWCVSSKIIDTHSKVYLDYNYGEVSELDLNDLLKHLC 553

Query: 529 HHF-PLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQ 587
            +F P+++ A     L +P  I     IVN    PT                       Q
Sbjct: 554 KYFPPVKVSALPRNNLLAPERITACFAIVNF---PTLR---------------------Q 589

Query: 588 NCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLR 647
              V  V ++Y  SW E         +S  E L T+   + + +  P      CY    R
Sbjct: 590 KATVEDVSVIYSTSWGETFL------KSGSEVLDTLWYDLQEVSPAPP-----CYVMVPR 638

Query: 648 GLIRTRVQQLVSECIELRLS 667
           G  + R+     E  EL  +
Sbjct: 639 GNQQARILGEFLEAHELNFT 658


>UniRef50_D2L1I3 Putative adenylate cyclase n=1 Tax=Desulfovibrio sp. FW1012B
            RepID=D2L1I3_9DELT
          Length = 1281

 Score =  574 bits (1480), Expect = e-162,   Method: Composition-based stats.
 Identities = 142/668 (21%), Positives = 256/668 (38%), Gaps = 45/668 (6%)

Query: 3    LYIETLKQRLDAI---NQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPK 59
            L+   +++R  A+   N+ R+  A   +G A      +LP L+                 
Sbjct: 640  LFSRDIRRRRLALLANNKRRLAWARRRLGEAGAAFLDMLPGLVGLGLVRDGSGTRPAPGA 699

Query: 60   GICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWV 119
             I  + PD     +L         +  + P   L +  VYT+GS  +V Q+  SDLD+W+
Sbjct: 700  RIAGFAPDLPTLRHLVRHFGCPAAAFPEVPANALAVEAVYTIGSVGTVAQTSDSDLDVWI 759

Query: 120  CHQSWLDS-EERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGST 177
            C +    +  +      K   +  +A +  G+E+ FF +     R N  G    E  GS 
Sbjct: 760  CLKDGEAAHPDLPAFTDKLETISRFAETEAGLEIHFFCMTVQDVRDNVFGYSEDEGYGSA 819

Query: 178  QHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWLDLGGLS 236
            Q  LL +EFYRTA+ +AG++  W  VP    +E Y   +  +         + LD G ++
Sbjct: 820  QGCLLKEEFYRTALVVAGRKPAWWCVPARIGQEAYAKALSGIRRAEPEVAADCLDFGPVT 879

Query: 237  SLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVS 296
            +++ +EYFGASLW + KS+ SP+K+++K  LLE Y+     P LL   +K  +   +   
Sbjct: 880  AIAGDEYFGASLWMIVKSLTSPFKSIIKFGLLEKYAEHPGEPELLCDTLKDYVFANQGGL 939

Query: 297  FGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVS 356
            +  DPY ++   V+ +    +    ++L+R+ F  K       E A       +L     
Sbjct: 940  WRCDPYALLFREVSRHYQERKQSGAVELLRQAFLQKTGFDPCEEYATRSGET-ILDHFFP 998

Query: 357  EWGWDEARLAMLDNRANWK----IDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASP 412
                          R +        Q     + +    +++Y  L   ++        + 
Sbjct: 999  YAPPAAGACPPPPRRDSQADEDGFAQAVALGDAITAYFLRAYERLKARSQELASGGGLTE 1058

Query: 413  QDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPN 472
            +D  +L+R++ A+F    GK+  + P I P         I          G+ +   +  
Sbjct: 1059 RDQTMLSRRIAASFGRRVGKIMRM-PFIRPGRDLFASLEIACEEISPREKGFVIRAESAG 1117

Query: 473  IESIIS-HQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGN---GIVDLPKLQEMVADVS 528
             +      + +     L +L  W   N L   R  L+++       + LP +  ++  V 
Sbjct: 1118 PDRKARKRETVRQEGSLPRLAGWLTANELY--RPGLHLQAAALPAPLTLPDVAGVLGAVH 1175

Query: 529  HHFPLRLPAPTPKAL-YSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQ 587
            + FP+R       +L   P  +     +VNL     A    +                  
Sbjct: 1176 NVFPVRETFAPALSLGLLPERVTAALFVVNL----LAPREERRT---------------- 1215

Query: 588  NCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALK--TILGKMHQDAAPPDSVEVFCYSQH 645
                 S+D+LY  +W E+  L       + +A     +   +    AP   +EV+  ++ 
Sbjct: 1216 ----VSLDVLYATTWGELFHLERTAGLDVFDASPSLFLSESLGLALAPDLRLEVYAPARS 1271

Query: 646  LRGLIRTR 653
                 R  
Sbjct: 1272 QCQAGRQA 1279


>UniRef50_Q1NP63 Adenylate cyclase n=2 Tax=delta proteobacterium MLMS-1
           RepID=Q1NP63_9DELT
          Length = 656

 Score =  571 bits (1471), Expect = e-161,   Method: Composition-based stats.
 Identities = 164/661 (24%), Positives = 298/661 (45%), Gaps = 42/661 (6%)

Query: 3   LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYL-DGNVPKGI 61
           + ++    R    N  R+ +++         +++ +P LL  ++  +PGY+ D   P+GI
Sbjct: 1   MSLKEKSNRYHRYNAERIAKSMMLNANKSNLIFAAVPYLLQVNNQDLPGYVADPACPRGI 60

Query: 62  CLYTPDETQRHYLNELELYRGMSVQDP---PKGELPITGVYTMGSTSSVGQSCSSDLDIW 118
           C + P                 + ++    P+    I  + T+GS  ++ QS  SD D W
Sbjct: 61  CDFDPTTLSGDLFRRFFPTAQATAREEMVLPRSSCAILSLKTIGSIGTIAQSEKSDCDYW 120

Query: 119 V-CHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGG-EDCGS 176
           V   Q  LD +  +LLQ+KC+ +E WA   GVEV FFL+D  + R N   S    E  GS
Sbjct: 121 VSVDQQQLDGQGLELLQQKCTAIEEWADKRGVEVHFFLMDITQTRENSFDSAAEDESAGS 180

Query: 177 TQHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDDYVMTLYAQGVLTPNEWLDLGGL 235
              ILL DE +RT V +AGK +LW  +P    E  Y   V  L  +  + P++++DLG +
Sbjct: 181 ALKILLKDELFRTHVLVAGKPLLWWFIPPGLNEGQYKALVARLIKERKIDPDDYVDLGYV 240

Query: 236 SSLSAEEYFGASLWQLYKSIDSPYKAVLKTLL-LEAYSWEYPNPRLLAKDIKQRL----- 289
           + +   E FGA LWQ+ K++DSP+K+V+K          +     L +  +K+ +     
Sbjct: 241 AGIPKAEIFGACLWQMNKALDSPFKSVIKFAYLELLLQQQQNALPLFSDKVKRLVTYPEK 300

Query: 290 ---HDGEIVSFGLDPYCMMLERVTEYLTA--IEDFTRLD-LVRRCFYLKVCEKL-SRERA 342
                  +V   +DPY ++   +  +     +E   +   L+R C +LK  E + S+++A
Sbjct: 301 LEDRMEALVPEEVDPYLLLAREIIAFYQQAKLEQMRKWSALIRECLFLKTLEGVESQKQA 360

Query: 343 CVGWRRAVLSQLVSEWGWD--EARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNL--- 397
            +G +  + + +     WD   A      +   W+  ++    N + + ++++Y+ L   
Sbjct: 361 KMGEKSHLKALMTQMETWDILPAEHQRFLDFRYWQYKELLALGNRIHEYLIETYKRLRWI 420

Query: 398 -IRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPP 456
             +F     L+   + +DI +L RKL+  +E    KV  +       ++  ++T I+V  
Sbjct: 421 FTKFGPDTGLT--ITERDISILGRKLFTFYEKKDNKVEYIRSISRQSMAMEDIT-IHVTK 477

Query: 457 GRANRSGWYLYNRAPNIESIISH--QPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNG- 513
              +R  +Y +    + E++ +     +  +  L +L+AW   NG+L S TRL++  N  
Sbjct: 478 -YDDRFFYYAFQGEQDHETVKTRVEAVIRRDDKLIRLLAWLLVNGMLASHTRLHLTKNFL 536

Query: 514 IVDLPKLQEMVADVSHHFP-LRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFR----- 567
            +DL  +Q +   +   FP +   A +P+ L     I    ++VN    P    +     
Sbjct: 537 PIDLVDIQGLAESMLATFPVVHFSAISPQQLLEQENILRALVVVNFFKQPVKGSKTLPST 596

Query: 568 --NQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILG 625
              +  + ++   D  +  + +N L   +   Y + WN      F   Q     +K +LG
Sbjct: 597 IITENSYGEYFTHDYQTLTQLKNALRALLTRHYVSRWNNNLEF-FIPHQDEANTIKQMLG 655

Query: 626 K 626
           K
Sbjct: 656 K 656


>UniRef50_D1U9E3 Putative adenylate cyclase n=1 Tax=Desulfovibrio aespoeensis Aspo-2
            RepID=D1U9E3_9DELT
          Length = 1291

 Score =  566 bits (1460), Expect = e-159,   Method: Composition-based stats.
 Identities = 153/666 (22%), Positives = 255/666 (38%), Gaps = 52/666 (7%)

Query: 2    YLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGI 61
             L     +QR+   N+ R+ RA+  +    Q    +LP LL          L+G  P  +
Sbjct: 658  ELTFMRREQRIQGFNRKRLVRAMGRLDRDKQAYLRMLPHLLETDVFETRFTLEGVPPCEV 717

Query: 62   CLYTPDETQRHYLNELELYRGMSVQDPPKG---ELPITGVYTMGSTSSVGQSCSSDLDIW 118
              YTP       L+ +EL R    +  P G    + I  VY MGS  +V Q+  SD+D W
Sbjct: 718  WGYTPT------LSAMELTRQFFPKIRPSGTRARVRILAVYAMGSLGTVAQTAQSDIDCW 771

Query: 119  VCHQSWLDSEERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGST 177
            VC    +D      L+RK   L  WA S  G+E  FF +  +  R N   S   E  GS 
Sbjct: 772  VCFDGDIDPNAEAGLRRKLDALGLWAESEFGIEAHFFPMRMDDVRDNRFSSGDEESSGSA 831

Query: 178  QHILLLDEFYRTAVRLAGKRILWNMVPCDEEE-HYDDYVMTLYAQGVLTPNEWLDLGGLS 236
            Q +LL +EFYRTAVR+AGK + W ++P   ++  YD  + +     V+      D G L+
Sbjct: 832  QALLLKEEFYRTAVRIAGKHLAWWVIPAGADKPTYDACIQSARRYPVMGRPRLEDFGHLA 891

Query: 237  SLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVS 296
             +  +EYFG SLWQ+ K++ SP+K+VLK  LLE Y+    +P  L   IK+ L      +
Sbjct: 892  PVPPDEYFGGSLWQMVKAVHSPFKSVLKLGLLETYADPATSPLPLCDRIKRNLFLNRRGT 951

Query: 297  FGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEK-----LSRERACVGWRRAVL 351
               DPY  +   +  Y   + D     L+   F  K   +     L R          ++
Sbjct: 952  RRTDPYASLFSTLRAYYADLGDAEAARLLTESFIFKANLRDILFFLGRPARAEDMS--LV 1009

Query: 352  SQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLS-VSA 410
            + L      +  +    +    W  ++  +    +   M+ +Y  + +    +  +    
Sbjct: 1010 ATLFGRECAEPEQRCHTN--VAWTFEKSLKMGASVRRYMVATYERIQQGLSGSGRTDAQI 1067

Query: 411  SPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRA 470
            + +D+  + R++ A F   P KV  V P +        +           +  W +   +
Sbjct: 1068 NAEDLTRMGRRIAANFSPRPHKVMRV-PFMDAAGGGFAILHFSASKAPGRKPAWLVRGGS 1126

Query: 471  PNIESIISH--QPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGN-GIVDLPKLQEMVADV 527
             +   + S   Q L  +     ++AW   N L + R+ L        + L  LQ+++  +
Sbjct: 1127 RSEAKLASSSLQLLHKSGDPVHMLAWLLANRLYSPRSLLQGDRTMAPISLADLQKLMPAM 1186

Query: 528  SHHFPLRLPAPTP-KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGEN 586
               FP             S   +     I NL   P +    Q                 
Sbjct: 1187 HEFFPFDQTFERDINEGLSSERVIRAFFIFNLTTAPDSRRIEQA---------------- 1230

Query: 587  QNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIE--ALKTILGKMHQDAAPPDSVEVFCYSQ 644
                     ++Y  +W E+    F+     +E    + +   +    A    + +F    
Sbjct: 1231 --------SIVYSTNWGEMYCRSFDKPGPELERQPSQFLAENLAHPIADIPEMILFIPKG 1282

Query: 645  HLRGLI 650
                 +
Sbjct: 1283 SQCKRV 1288


>UniRef50_C4XU05 Putative uncharacterized protein n=1 Tax=Desulfovibrio magneticus
           RS-1 RepID=C4XU05_DESMR
          Length = 608

 Score =  566 bits (1459), Expect = e-159,   Method: Composition-based stats.
 Identities = 148/634 (23%), Positives = 250/634 (39%), Gaps = 46/634 (7%)

Query: 37  LLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPIT 96
           +LP L+          L       I    P+             R       P   + I 
Sbjct: 1   MLPALVQAPLVRDDNGLRPAPAARIAGQVPNLATARLTAAHFGDRATEAATLPDDAIRIE 60

Query: 97  GVYTMGSTSSVGQSCSSDLDIWVC-HQSWLDSEERQLLQRKCSLLENWAA-SLGVEVSFF 154
            VYT+GS  +V Q+  SDLD+WV   ++     +    Q K   +   A     +E+ FF
Sbjct: 61  AVYTIGSVGTVAQTDDSDLDVWVVLAEADATRPDLPAFQDKLDAVSRQADRDHNLEIHFF 120

Query: 155 LIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCD-EEEHYDD 213
           L+  +  R N  G    E  GS Q  LL +EFYRTA+ +AGK+  W  +P D  EE Y  
Sbjct: 121 LMSVSDIRDNIFGYSADEGYGSAQGCLLKEEFYRTALVVAGKKPAWWCLPPDIAEEGYAK 180

Query: 214 YVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSW 273
            +  L         + LD G + +++ +EYFGASLW + KS+ SP+K+++K  LLE Y+ 
Sbjct: 181 AMAALGRTAADVAADCLDFGCVRAIAGDEYFGASLWMIVKSLTSPFKSIIKFGLLEKYAA 240

Query: 274 EYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKV 333
               P LL + +K  +   +   +  DPY ++ + V+ +         ++L+R+ F  K 
Sbjct: 241 HPGRPSLLCETLKASILANQGGLWRCDPYALLFKEVSRHYEESGQAGAMELLRQAFLQKT 300

Query: 334 CEKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWK----IDQVREAHNELLDA 389
                 E A      A+L                L  +A  +      Q     + + + 
Sbjct: 301 GFDPCDEYASRTGE-AILDHFFPYAPPATGSCPPLPKKAGAEAETGFAQGMVLCDAISNY 359

Query: 390 MMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNL 449
            +++Y  L   +     +   + +D  +L+R++ A+F    GKV  + P + P     + 
Sbjct: 360 FLKAYERLKNRSAELGAAGGLTERDQAMLSRRIAASFAKRVGKVMRL-PFLRPGRHLFDS 418

Query: 450 TFIYVPPGRANRSGWYLYNRAPNIESIIS----HQPLEYNRYLNKLVAWAWFNGLLTSRT 505
             I +  G+   +G  +    P +          + L     + +L AW   N L   R 
Sbjct: 419 LEIGLEDGKGREAG-LVVRGEPAVRGGARKSRQKETLRQELSVVRLAAWLVANELY--RP 475

Query: 506 RLYIKGN---GIVDLPKLQEMVADVSHHFPLRLPAPTPKAL-YSPCEIRHLAIIVNLEYD 561
            L+++       + LP    +++ V   FP R     P +   SP ++    ++VN+   
Sbjct: 476 GLHVQATLLPAPLTLPDCVGLLSAVHDLFPARATFNPPLSWGLSPEKVTAALLVVNM--- 532

Query: 562 PTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTL-HFNGEQSM-IEA 619
            TA    +                       S+D LY  SW E   L    G +S+ I  
Sbjct: 533 -TAPREERAT--------------------VSIDTLYATSWGEFFHLERTTGLESLGISP 571

Query: 620 LKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTR 653
              ++  M     P   ++VF  ++ L   +R  
Sbjct: 572 RDYLIDSMGLTLDPDARIKVFAPAKSLCQAVRRA 605


>UniRef50_C6BYH9 Putative adenylate cyclase n=1 Tax=Desulfovibrio salexigens DSM 2638
            RepID=C6BYH9_DESAD
          Length = 1306

 Score =  561 bits (1446), Expect = e-158,   Method: Composition-based stats.
 Identities = 152/633 (24%), Positives = 255/633 (40%), Gaps = 48/633 (7%)

Query: 3    LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNV-PKGI 61
              IE         N  R+D A + +    +++  ++P LLH +   +   LD       +
Sbjct: 679  KDIEHCHACFAENNSRRLDWAQSKLDSKSRKLLKIIPALLHTNVFEIKSGLDPQTMSSRV 738

Query: 62   CLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCH 121
            C Y         L+E      +  +   +   PI    ++GST ++ Q+  SDLD WVC 
Sbjct: 739  CNYALSPQVIKLLDEFF--PDIKYEISKESSTPIEAFMSIGSTGTIAQTPDSDLDCWVCC 796

Query: 122  Q-SWLDSEERQLLQRKCSLLENWAA-SLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQH 179
              +   +E RQ L  K   +E WA    G+E+ FF++D    R N  G    E  GS Q 
Sbjct: 797  NFTGRSAESRQNLGVKLQAIEKWAMNEFGLEIHFFIMDTREIRDNLFGLSDEESSGSAQS 856

Query: 180  ILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLT-PNEWLDLGGLSSL 238
             +L +EFYRTAV LAGK  LW   P +  E    Y  T     +L   N  +DLG + ++
Sbjct: 857  AILKEEFYRTAVLLAGKPPLWWFTPPEAAE--KAYADTKKKVALLKGKNFCVDLGNIPNI 914

Query: 239  SAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFG 298
              EE+FGASLWQ+ K I SP+K+++K  LLE Y+ +     LL + +K+ +  G+     
Sbjct: 915  PVEEFFGASLWQIVKGIKSPFKSIMKFGLLELYTSD-SKYSLLCEKLKKNIISGKRRIRR 973

Query: 299  LDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVS-E 357
            +DPY  + + +  +  A E    + L      LK    +S +       RA   +L+   
Sbjct: 974  VDPYMRLYQDLANFYRANEKDEYIWLTAMALRLKCGL-VSEKEILSTPSRAEEIELIDFT 1032

Query: 358  WGWDEARLAMLDNRANWK-IDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIG 416
                       +N  +      V E    +   M+ +Y   +R  +     VS +P+D+ 
Sbjct: 1033 MKLSGEETGAFENFKDLSDFGSVAELGRRVNQFMVNTYMK-VRGEQDKFPGVSITPEDLT 1091

Query: 417  VLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSG--WYLYNRAPNIE 474
             L R +++AF     K+  +       L  P   F           G  W ++   P+  
Sbjct: 1092 RLGRIIFSAFAKRTNKILRL------SLPGPRTHFFNSINISRTEDGKIWNIHGEYPDES 1145

Query: 475  SIISHQP-LEYNRYLNKLVAWAWFNGLLTSRTRLYIK-GNGIVDLPKLQEMVADVSHHFP 532
               +    +E    LN ++ W   NGL     ++     +G +   +++++ +++   FP
Sbjct: 1146 GARNILTRIESGPDLNFMLVWLALNGLYNQEMQIKTDISSGPLREREIKKLFSELMRFFP 1205

Query: 533  LRLPAPTP-KALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLV 591
             +     P +   +   +     IVNL   P +    +                      
Sbjct: 1206 PKKTFNVPIEETLNTERLTKGFFIVNLCVPPESKKVQE---------------------- 1243

Query: 592  GSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL 624
              V L+Y  +W EV          ++E  +  L
Sbjct: 1244 --VHLVYSTNWGEVFCKPLKINMKLVETPEQYL 1274


>UniRef50_C0N363 Putative uncharacterized protein n=1 Tax=Methylophaga thiooxidans
           DMS010 RepID=C0N363_9GAMM
          Length = 827

 Score =  555 bits (1431), Expect = e-156,   Method: Composition-based stats.
 Identities = 163/822 (19%), Positives = 318/822 (38%), Gaps = 95/822 (11%)

Query: 48  LMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSV 107
           ++PG+++ +VP G+  Y PD+T      ELE       +       P+ G+Y +     +
Sbjct: 1   MLPGFINDDVPAGLIDYQPDKTTLDKAKELET--SFKYRRKALRRYPLRGLYLIHPQGVL 58

Query: 108 GQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESG 167
             + +  L +W+ H + ++ E+RQ L  K   + +W  + G+ V + L+ E     N   
Sbjct: 59  NATDNGPLQLWLLHSNNVNDEQRQGLTLKLDAVVDWMQAAGLTVEYKLLAEADLHTN--- 115

Query: 168 SLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPN 227
           SL G +         +D  Y + + LAG    W +    E++ Y   +  +  Q +L   
Sbjct: 116 SLQGWE---------IDLLYHSGMVLAGSVPYWWLSTTAEDQDYQHTINEIKNQRMLNQV 166

Query: 228 EWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRL--LAKDI 285
            ++D G  +   AE  F       Y++I +   +    L LE    +     L  L+  +
Sbjct: 167 SFVDFGAAAPSHAERIFTLC----YQAIKNSLHSGNDWLELEYLHTQLEQDELPCLSHLL 222

Query: 286 KQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSR--ERAC 343
           KQ++H  ++ S   D   + L ++ ++  A          R   YL   E LS+  ++A 
Sbjct: 223 KQQVHQQKL-SLSHDISHLKLLQIAQHNPASH-------AREALYLVSSELLSKSVKQAR 274

Query: 344 VGWRRAVLSQLVSEWGWDEARLAMLDNRANW----KIDQVREAHNELLDAMMQSYRNLIR 399
             WRRA +  LV +W W E +L  LD R         + + E+ + LL  M         
Sbjct: 275 YPWRRAFIQSLVEQWNWSEEKLQQLDQRDYAANKRCFELIGESCHRLLKQMTD------- 327

Query: 400 FARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRA 459
           FAR + L V +    +  L +     F+     +  +  Q+ P  S  +  F++      
Sbjct: 328 FAREHALEVDSQ---LAELKKCYQLRFKPAADVIDCLPKQMRPA-SNSDRLFLH---RFQ 380

Query: 460 NRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPK 519
           N S W++  +        +   L  +  L  ++AWA  N +L+    L +       L K
Sbjct: 381 NHSDWFISFQLLQ---KPTDSALFRHESLLHVLAWAVSNQILSRSNWLSVNDQ----LQK 433

Query: 520 LQ-EMVADVSHHFPLRLPAPT-----PKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHF 573
           +    V ++S H   R  A +       A   P  I+ + +I NLE   + +   Q +  
Sbjct: 434 VSTNTVVELSQHVFRRHLADSDLFTHSNAATQPESIQQIMLISNLERQASDSLSQQGLQL 493

Query: 574 DFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAP 633
             ++ D F++  ++  LV SVD L  ++  +  +   N + + +E L  +L      +  
Sbjct: 494 SSKQNDPFNYTSSRQSLVLSVDGLLLSNTGQWHSFALNDDHAPLELLIYLLN-WQPSSLT 552

Query: 634 PDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERL 693
            +++  +C +      I  R+  L ++    R      + GR   L  +G+ + L ++  
Sbjct: 553 QENISGWCPTPIFGQSITQRLNSLTAQL--CRHYQQFPQHGRL-LLNYAGRAYSLQWQDN 609

Query: 694 NVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDEN 753
                +   + + + A++ N+       ++              S+G+  +  ++    N
Sbjct: 610 QADYTRRPASQDLWQALAENRHVFTPSALDNY----------LDSDGLFNYLLQKQA-SN 658

Query: 754 GFNIYILDESNRVEVY-----------HHCEGSKEELVRDVSRFYSSSHDRFTYGSSFIN 802
             +++I  E N +  Y                ++  LV  + +F S   +          
Sbjct: 659 SISVFIYLEQNTIICYLIDELGNLIRQQFQHLTESTLVAHLHKFLSEIKNTRQIDQ---- 714

Query: 803 FNLPQFYQIVKVDGREQVIPFR-TKSIGNMPPANQDHDTPLL 843
               +FY++ +     Q +            P      +P L
Sbjct: 715 ---LRFYRLRREKQGWQRVALATPAQTRGYLPITVTMTSPAL 753


>UniRef50_C0QEU2 CyaA2 n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QEU2_DESAH
          Length = 1302

 Score =  540 bits (1392), Expect = e-152,   Method: Composition-based stats.
 Identities = 160/640 (25%), Positives = 283/640 (44%), Gaps = 61/640 (9%)

Query: 9    KQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDG--NVPKGICLYTP 66
            ++     N+L +  A+    P    ++ ++P L+H +    PGY       P+GI  Y P
Sbjct: 683  EKLFLNQNRLSILTAMDVFKPKQADLFEIIPLLIHENIDF-PGYQADLEQSPRGIAEYRP 741

Query: 67   ----DETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQ 122
                 +T   Y+N  +L    S          + G++TMGST ++ Q+  SD+D WVC +
Sbjct: 742  CKQTVKTASRYVNTGKLECRFS------ELPHVEGLFTMGSTGTIAQAPDSDIDYWVCVR 795

Query: 123  SWLDSE--ERQLLQRKCSLLENWA-ASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQH 179
               D E  E +  Q+K +LLE WA      E+ FF++D +R R ++ G    E  GS Q 
Sbjct: 796  -GYDPECMEEKRFQQKLTLLEQWALGKFKTEIHFFIVDIDRARIDDFGDSTRESSGSAQG 854

Query: 180  ILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLS 239
            ++L +EFYRT + +AGK   W  +P      Y   +++           ++D G +  + 
Sbjct: 855  MILKEEFYRTMIHVAGKLPFWCTLPVSVSREYYGLLLSRICANRF-QCRFIDFGDIHEIP 913

Query: 240  AEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHD-GEIVSFG 298
            +  YFGAS+WQL+K ++SP+K+V+K  LLE + +     +LL    K +  D G  +  G
Sbjct: 914  SAAYFGASIWQLFKLLESPFKSVIKMALLEEFLYARGKKQLLCNRFKAQWMDPGLYLPLG 973

Query: 299  -LDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC--EKLSRERACVGWRRAVLSQLV 355
             +DPY ++L+ + +Y   + +     LV++CF+LK    +    +      R   +++ +
Sbjct: 974  KIDPYYILLKSLVDYYGQVNNPAAERLVQQCFFLKTGITKDSDLDETLFSMRSFFITRAM 1033

Query: 356  SEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDI 415
             EW W    +    N   W+   +     ++   M+++Y  + +   R   ++  +P+D 
Sbjct: 1034 DEWAWTRKMVFENGNFRQWQYLSITRLSRQIQQYMVKTYIRINQAIDREQCAM-ITPEDR 1092

Query: 416  GVLTRKLYAAFEALPGKV--TLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNI 473
             VL RK++  F + PGK+  TL+  +     +   LT++         S W L NR    
Sbjct: 1093 TVLGRKMFVEFSSQPGKIPKTLMVSRSDRHFTSLVLTYL---SQTGKPSQWALVNRFSRS 1149

Query: 474  ESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNG-IVDLPKLQEMVADVSHHFP 532
                S + +     + ++ AW   N L +  T + +  N   V    +Q +   +   F 
Sbjct: 1150 AP-ESREVIRQAETIEEIAAWFIQNQLFSPSTIINLLPNPTPVSSNDIQGLFQALYRFFN 1208

Query: 533  LRL-PAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLV 591
                 +P  K L S   I  + I +NL        + + +H                   
Sbjct: 1209 HDNGKSPGSKNLLSKARITAIFISINLCV----PRKKRRIHDSSA--------------- 1249

Query: 592  GSVDLLYRNSWNEVRTLHFNGEQS------MIEALKTILG 625
                 +Y NSW E+  +  + +Q       ++E LKT+L 
Sbjct: 1250 -----IYLNSWGEMFCIRISSQQGFVLRDEILERLKTMLE 1284


>UniRef50_C0ARX7 Putative uncharacterized protein n=1 Tax=Proteus penneri ATCC 35198
           RepID=C0ARX7_9ENTR
          Length = 363

 Score =  510 bits (1314), Expect = e-143,   Method: Composition-based stats.
 Identities = 249/345 (72%), Positives = 289/345 (83%), Gaps = 1/345 (0%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           +YLYIETLKQRLDAINQLR++RA A+M   F+QVY L+P LLHYHHP +PGY+ GNVP G
Sbjct: 19  LYLYIETLKQRLDAINQLRLERAFASMCDVFKQVYGLIPVLLHYHHPELPGYIQGNVPHG 78

Query: 61  ICLYTPDETQRHYLNEL-ELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWV 119
            C + PD+ QR + N+L        ++    GELPITG+Y+MGSTSS+GQS  SD+DIWV
Sbjct: 79  TCFFEPDDMQRQWANKLINALCDEPMEGYASGELPITGIYSMGSTSSIGQSHCSDIDIWV 138

Query: 120 CHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQH 179
           CHQSWLD +ER LLQRKC L+E WA  LG++V+FFLIDENRFRH+ SGSLGGEDCGSTQH
Sbjct: 139 CHQSWLDQDERALLQRKCQLIEQWAGELGIDVTFFLIDENRFRHHASGSLGGEDCGSTQH 198

Query: 180 ILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLS 239
           ILLLDEFYRTAVRLAGKR+LW MVP +EE HYD+YV +LYAQGVLTPNEWLDLGGL  LS
Sbjct: 199 ILLLDEFYRTAVRLAGKRLLWTMVPVEEEHHYDEYVNSLYAQGVLTPNEWLDLGGLGELS 258

Query: 240 AEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGL 299
           AEEYFGASLWQLYKS+DSPYKAVLK++LLEAYS +YPN +LLA ++KQ LH GEIV++GL
Sbjct: 259 AEEYFGASLWQLYKSVDSPYKAVLKSILLEAYSADYPNGKLLALEMKQHLHRGEIVNYGL 318

Query: 300 DPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACV 344
           D YCMMLERVT YL +I D TRLDL+RRCFYLKVCEKLS E+   
Sbjct: 319 DAYCMMLERVTRYLVSINDLTRLDLIRRCFYLKVCEKLSNEKNTK 363


>UniRef50_Q2LSY1 Adenylate cyclase n=1 Tax=Syntrophus aciditrophicus SB
           RepID=Q2LSY1_SYNAS
          Length = 653

 Score =  490 bits (1262), Expect = e-137,   Method: Composition-based stats.
 Identities = 154/638 (24%), Positives = 274/638 (42%), Gaps = 62/638 (9%)

Query: 9   KQRLDAINQLRVDRALAAMGPA-FQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPD 67
           K      N+ R  R  + + P   + +  LLP +L  +   +PGY+D  + +   ++  +
Sbjct: 32  KSIFLEYNRFR-KRLFSELAPKDSEIILYLLPWMLSVNDVSIPGYVDH-IKQNFRVFNIE 89

Query: 68  ------ETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC- 120
                 + +R +     +   ++V  P +  LP+ G+YT+GS  ++ Q+ SSD D+W+C 
Sbjct: 90  TEKDILKRERLFKKTFHIRNDLTVLKPAEKSLPVEGIYTIGSVGTISQTSSSDCDLWICI 149

Query: 121 HQSWLDSEERQLLQRKCSLLENWAAS-LGVEVSFFLIDENRFRHNESGSLGGEDCGSTQH 179
            ++  D E   LL  K   +++W  S L + V FFL D    R    G +  E CGSTQ 
Sbjct: 150 DKTLYDEEAFDLLTLKIDRIKDWMDSRLKMPVCFFLCDVEDIRACRFGGVDCESCGSTQK 209

Query: 180 ILLLDEFYRTAVRLAGKRILWNMVPCDEEEH--YDDYVMTLYAQGVLTPNEWLDLGGLSS 237
            +L +EFYRTA+  AGK  LW  V  D  +   YDD V   +        + +DLG L  
Sbjct: 210 KVLKEEFYRTAILTAGKIPLWW-VAWDRRQTLCYDDAVRE-WQSAPSVYYDLIDLGNLDF 267

Query: 238 LSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSF 297
           +   E FGA+LWQ  KS+  P K++LK LLL+    E P   LL    ++ + D      
Sbjct: 268 IDKRESFGAALWQFNKSLTHPLKSILKMLLLKM-FLESPKEELLCHRFRRLILDQPRKPH 326

Query: 298 G-LDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVS 356
             +DP    L  V ++   ++  T L  + +CFYL+   KL      V    A+  +L  
Sbjct: 327 SFVDPGAFTLIAVLDFYQNMDPQT-LQFILKCFYLRYKVKLFSRTMTVKEETAL--ELFR 383

Query: 357 EWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIG 416
            +G D   +  L+  ++W           ++  ++  Y+++   AR   ++   + QD+ 
Sbjct: 384 RYGLDRETIYELNRFSSWTYSSQIRFGEFIVLLLVDIYKDIAHIARD--VTGDVAAQDLT 441

Query: 417 VLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESI 476
           +L +KL A+ +  P K+ +++  +   L  P+LT       R   + W ++    +   I
Sbjct: 442 ILGQKLSASLKKKPHKIPVLSKPLET-LKMPSLTL------RFCENRWQVFPDNDDGAMI 494

Query: 477 ISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGI-VDLPKLQEMVADVSHHFPLR- 534
           +  + L Y       +AW   N L     +L +  N     + ++  ++  +   F +  
Sbjct: 495 VEKRDLVYC---LAYLAW---NDLYFPG-QLRMLPNPTSAAMQEIINLLQKIREVFGVYD 547

Query: 535 LPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSV 594
           + +   +    P     L II+N    P A                         ++ ++
Sbjct: 548 VSSIDFQNFLQPEHTEKLLIIINFAAPPHAD------------------------VIHTL 583

Query: 595 DLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAA 632
            ++  N+W E+    F  ++  I  L+ I    +    
Sbjct: 584 SVIRLNNWGELFVNRFTLQERFISFLENIAESSYNTVE 621


>UniRef50_UPI00019102CE adenylate cyclase n=2 Tax=Salmonella enterica subsp. enterica
           serovar Typhi RepID=UPI00019102CE
          Length = 186

 Score =  295 bits (755), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 180/186 (96%), Positives = 182/186 (97%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPSG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           IC YTPDETQRHYLNELELYRGM+ QDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC
Sbjct: 61  ICFYTPDETQRHYLNELELYRGMTPQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180
           HQSWLD EERQLLQRKCSLLE+WAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI
Sbjct: 121 HQSWLDGEERQLLQRKCSLLESWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHI 180

Query: 181 LLLDEF 186
           LLLDEF
Sbjct: 181 LLLDEF 186


>UniRef50_C0ARX6 Putative uncharacterized protein n=1 Tax=Proteus penneri ATCC 35198
           RepID=C0ARX6_9ENTR
          Length = 248

 Score =  280 bits (717), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 177/228 (77%), Positives = 198/228 (86%), Gaps = 1/228 (0%)

Query: 340 ERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIR 399
           +    GWRR VLSQLV++W WD  RL +LD R +WKI++VR+AHNELLD MMQSYRNLIR
Sbjct: 10  QNESEGWRRQVLSQLVTQWQWDNERLTILDTRDSWKIERVRDAHNELLDTMMQSYRNLIR 69

Query: 400 FARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRA 459
           FARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSE +LTFIYVP GRA
Sbjct: 70  FARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSESHLTFIYVPQGRA 129

Query: 460 NRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYI-KGNGIVDLP 518
           NRSGWYLYNRAP+ E+I+ HQPLEYNRYLNKLVAW++FNGLLT  +R+YI +G    D  
Sbjct: 130 NRSGWYLYNRAPDFENIVGHQPLEYNRYLNKLVAWSYFNGLLTKESRVYIHQGESSCDEI 189

Query: 519 KLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF 566
           KL E+V D+S HFP+RLPAPTPKALYSPCEIRHLAIIVNLE DPT +F
Sbjct: 190 KLHELVRDMSSHFPIRLPAPTPKALYSPCEIRHLAIIVNLETDPTESF 237


>UniRef50_D1U0N4 Conserved domain protein n=1 Tax=Yersinia pestis KIM D27
           RepID=D1U0N4_YERPE
          Length = 223

 Score =  249 bits (635), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 132/171 (77%), Positives = 148/171 (86%)

Query: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKG 60
           MYLYIETLKQRLDAINQLRVDRALAAMGPAFQ+VYSLLP LLH HHP MPGYLDGNVP G
Sbjct: 1   MYLYIETLKQRLDAINQLRVDRALAAMGPAFQKVYSLLPILLHCHHPQMPGYLDGNVPHG 60

Query: 61  ICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVC 120
           +CL+TP+E Q+ YL ++E   G  +     GELPITGVY+MGSTSS+GQ  +SDLDIWVC
Sbjct: 61  VCLFTPNEIQQDYLADVEARWGEPLAPSAGGELPITGVYSMGSTSSIGQCHTSDLDIWVC 120

Query: 121 HQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENRFRHNESGSLGG 171
           HQ+WLD+EER  LQ+KCSLLE WAAS+GVEVSFFL+DENRFRHN SGSLGG
Sbjct: 121 HQAWLDTEERNQLQQKCSLLEKWAASMGVEVSFFLVDENRFRHNASGSLGG 171


>UniRef50_C4TXU8 Putative uncharacterized protein n=4 Tax=Enterobacteriaceae
           RepID=C4TXU8_YERKR
          Length = 149

 Score =  181 bits (460), Expect = 9e-44,   Method: Composition-based stats.
 Identities = 112/145 (77%), Positives = 128/145 (88%)

Query: 700 LENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYI 759
           +ENA+EFYGAIS+NKLHGLS+QVE + + LP VVDGFASEGIIQFFFE T DE GFNIYI
Sbjct: 1   MENAVEFYGAISNNKLHGLSIQVEADQIHLPPVVDGFASEGIIQFFFEGTADEKGFNIYI 60

Query: 760 LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQ 819
           LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIV++DGR Q
Sbjct: 61  LDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVQLDGRTQ 120

Query: 820 VIPFRTKSIGNMPPANQDHDTPLLQ 844
           VIPFR+ ++ ++  A+++   P  Q
Sbjct: 121 VIPFRSNALSHLHIADKETSAPAQQ 145


>UniRef50_UPI000169845A putative adenylate cyclase n=1 Tax=Endoriftia persephone
           'Hot96_1+Hot96_2' RepID=UPI000169845A
          Length = 255

 Score =  132 bits (331), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 29/186 (15%), Positives = 63/186 (33%), Gaps = 8/186 (4%)

Query: 649 LIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYG 708
            +  R+  L    +     + +   G   A R+S   + +  +      + L++   F  
Sbjct: 46  QVAQRLTGLYRHILG--YFNQQPGHGGRYAFRISEAFYLIQQKEQGFQWRNLDSFEHFLQ 103

Query: 709 AISHNKLHGLSVQVETNHV-KLP-AVVDGFASEGIIQFFFEETQDENGFNIYILDESNRV 766
           A+   +     +Q++   + + P   +       +IQ FF   +      IY+LDE   +
Sbjct: 104 ALETPQHVFQPLQIDPRILRQTPYPALYRHNKPDLIQLFFHVQR--ESVQIYLLDEQGAL 161

Query: 767 EVYHHCEGSKEELVRDVSRFYSSSHDRFTY--GSSFINFNLPQFYQIVKVDGREQVIPFR 824
                   S   ++    RF +S         G +       +FY++ +    +  I  R
Sbjct: 162 FRQSMLMDSPRFMMLQQRRFLNSLQQLRLMLPGGAGNLLAETEFYELKQAPSGDWSIERR 221

Query: 825 TKSIGN 830
              +  
Sbjct: 222 RVPLNG 227


>UniRef50_A4P0R1 Adenylate cyclase n=2 Tax=Haemophilus influenzae
          RepID=A4P0R1_HAEIN
          Length = 102

 Score = 73.1 bits (178), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 23/57 (40%), Positives = 34/57 (59%)

Query: 1  MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNV 57
          M   +   KQ + A++Q R +RAL   G AFQ V +++P LLH +HP +PGY+    
Sbjct: 1  MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAVIPLLLHLNHPQLPGYVIHAP 57


>UniRef50_UPI0001699E12 hypothetical protein Epers_06677 n=1 Tax=Endoriftia persephone
          'Hot96_1+Hot96_2' RepID=UPI0001699E12
          Length = 77

 Score = 59.7 bits (143), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 21/62 (33%), Positives = 37/62 (59%)

Query: 3  LYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGIC 62
            ++ ++QR   +++ R+ R L  + P  Q +  LLP L H +HP++PGY++  VP GI 
Sbjct: 16 KDLKIIRQRFQRLHRERLRRILGELRPTQQDLLQLLPLLFHINHPVLPGYINSKVPAGIP 75

Query: 63 LY 64
           +
Sbjct: 76 DF 77


>UniRef50_B8R1B0 DNA-directed RNA polymerase n=2 Tax=Volvox carteri RepID=B8R1B0_VOLCA
          Length = 2094

 Score = 47.7 bits (112), Expect = 0.002,   Method: Composition-based stats.
 Identities = 41/222 (18%), Positives = 71/222 (31%), Gaps = 20/222 (9%)

Query: 488  LNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPC 547
            LNKL ++   N L +S   L IK N +  L   +  +   + HF + L   T K L S  
Sbjct: 1012 LNKLTSYLLQNKLFSS---LKIKPNTVQTLFDFRLNLNVFTKHFLIYLVNFTNKTLLSKE 1068

Query: 548  EIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRT 607
                     NLE         + +      L  F+F   +        +L  N  N++ T
Sbjct: 1069 -----LKNFNLENRAQNKKNQEALFILTNSLKAFNFRILEKHTTKLAVMLLLNLTNQITT 1123

Query: 608  LHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGL-IRTRVQQ-LVSECIELR 665
               N    +I A       +    A    +  +  S  +    ++  ++  LV       
Sbjct: 1124 KSRN----IIRAPFYF--GLQNKTAKIQKLCTYATSVSITFNFLKHAIKTKLVQRLYFCY 1177

Query: 666  LSSTRQETGRFKALRVSGQTW----GLFFERLNVSVQKLENA 703
            L     +  +   +      W     + F    +  QK+   
Sbjct: 1178 LFKQGLQLKKKAIMMTKNHGWKKQTKIQFVLRQILQQKIPEL 1219


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.310    0.137    0.379 

Lambda     K      H
   0.267   0.0420    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,544,087,662
Number of Sequences: 3077464
Number of extensions: 178192832
Number of successful extensions: 481840
Number of sequences better than 1.0e-01: 49
Number of HSP's better than  0.1 without gapping: 102
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 481082
Number of HSP's gapped (non-prelim): 169
length of query: 848
length of database: 1,040,396,356
effective HSP length: 138
effective length of query: 710
effective length of database: 615,706,324
effective search space: 437151490040
effective search space used: 437151490040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 98 (42.3 bits)