Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37760
DateThu Jan 5 11:57:33 GMT 2012
Unique Job IDc1163adf2843630f

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1n2sa_
Top template information
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
Confidence and coverage
Confidence:100.0% Coverage:100%
298 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNILLFGKTGQVGWELQRALAPLGNLIAFDVHSTDYCGDFSNPEGVAETVRSIRPDIIVN
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  AAAHTAVDKAESEPEFAQLINATSVEAIAKAANEVGAWVIHYSTDYVFPGNGDMPWLETD
Secondary structure 
SS confidence 
Disorder 
?????
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ATAPLNVYGETKLAGEKALQEYCAKHLIFRTSWVYAGKGNNFAKTMLRLAKEREELAVIN
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  DQFGAPTGAELLADCTAHAIRVALNKPDVAGLYHLVASGTTTWYDYAALVFEEARKAGIP
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........
Sequence  LALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFALVLPDWQVGVKRMLNELFTTTAI
Secondary structure 
SS confidence 
Disorder  ?
?????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1n2s chain A

3D model

Region: 1 - 298
Aligned: 298
Modelled: 298
Confidence: 100.0%
Identity: 85%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1z7e chain C

3D model

Region: 1 - 296
Aligned: 294
Modelled: 296
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna

Phyre2

PDB 1z45 chain A

3D model

Region: 2 - 295
Aligned: 274
Modelled: 271
Confidence: 100.0%
Identity: 19%
PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose

Phyre2

PDB 1vl0 chain A

3D model

Region: 1 - 293
Aligned: 278
Modelled: 292
Confidence: 100.0%
Identity: 35%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3sc6 chain F

3D model

Region: 1 - 292
Aligned: 278
Modelled: 289
Confidence: 100.0%
Identity: 37%
PDB header:oxidoreductase
Chain: F: PDB Molecule:dtdp-4-dehydrorhamnose reductase;
PDBTitle: 2.65 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 reductase (rfbd) from bacillus anthracis str. ames in complex with3 nadp

Phyre2

PDB 1i24 chain A

3D model

Region: 2 - 295
Aligned: 285
Modelled: 288
Confidence: 100.0%
Identity: 17%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2pzl chain B

3D model

Region: 1 - 297
Aligned: 278
Modelled: 284
Confidence: 100.0%
Identity: 17%
PDB header:sugar binding protein
Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp

Phyre2

PDB 2pk3 chain B

3D model

Region: 1 - 296
Aligned: 287
Modelled: 287
Confidence: 100.0%
Identity: 12%
PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase

Phyre2

PDB 1db3 chain A

3D model

Region: 2 - 295
Aligned: 291
Modelled: 294
Confidence: 100.0%
Identity: 14%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2q1w chain C

3D model

Region: 1 - 297
Aligned: 279
Modelled: 280
Confidence: 100.0%
Identity: 17%
PDB header:sugar binding protein
Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+

Phyre2

PDB 2ydy chain A

3D model

Region: 2 - 294
Aligned: 252
Modelled: 259
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine adenosyltransferase 2 subunit beta;
PDBTitle: crystal structure of human s-adenosylmethionine synthetase2 2, beta subunit in orthorhombic crystal form

Phyre2

PDB 1kew chain A

3D model

Region: 1 - 295
Aligned: 292
Modelled: 295
Confidence: 100.0%
Identity: 16%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2z1m chain C

3D model

Region: 2 - 295
Aligned: 291
Modelled: 294
Confidence: 100.0%
Identity: 16%
PDB header:lyase
Chain: C: PDB Molecule:gdp-d-mannose dehydratase;
PDBTitle: crystal structure of gdp-d-mannose dehydratase from aquifex aeolicus2 vf5

Phyre2

PDB 1oc2 chain A

3D model

Region: 1 - 295
Aligned: 281
Modelled: 282
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 3icp chain A

3D model

Region: 1 - 296
Aligned: 275
Modelled: 281
Confidence: 100.0%
Identity: 16%
PDB header:isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of udp-galactose 4-epimerase

Phyre2

PDB 1t2a chain A

3D model

Region: 2 - 295
Aligned: 291
Modelled: 294
Confidence: 100.0%
Identity: 15%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2x4g chain A

3D model

Region: 1 - 297
Aligned: 281
Modelled: 289
Confidence: 100.0%
Identity: 12%
PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa

Phyre2

PDB 2yy7 chain B

3D model

Region: 1 - 293
Aligned: 283
Modelled: 284
Confidence: 100.0%
Identity: 15%
PDB header:oxidoreductase
Chain: B: PDB Molecule:l-threonine dehydrogenase;
PDBTitle: crystal structure of thermolabile l-threonine dehydrogenase from2 flavobacterium frigidimaris kuc-1

Phyre2

PDB 2p5u chain C

3D model

Region: 1 - 296
Aligned: 284
Modelled: 285
Confidence: 100.0%
Identity: 20%
PDB header:isomerase
Chain: C: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad

Phyre2

PDB 2bll chain A domain 1

3D model

Region: 1 - 296
Aligned: 287
Modelled: 296
Confidence: 100.0%
Identity: 14%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2
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d1n2sa_
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c1z7eC_
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c1z45A_
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d1vl0a_
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c3sc6F_
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d1i24a_
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c2pzlB_
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c2pk3B_
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d1db3a_
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c2q1wC_
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c2ydyA_
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d1kewa_
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c2z1mC_
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d1oc2a_
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c3icpA_
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d1t2aa_
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c2x4gA_
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c2yy7B_
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c2p5uC_
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d2blla1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1n2sa_
100.0 85 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
2c1z7eC_
100.0 14 PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna
3c1z45A_
100.0 19 PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose
4d1vl0a_
100.0 35 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
5c3sc6F_
100.0 37 PDB header:oxidoreductase
Chain: F: PDB Molecule:dtdp-4-dehydrorhamnose reductase;
PDBTitle: 2.65 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 reductase (rfbd) from bacillus anthracis str. ames in complex with3 nadp
6d1i24a_
100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
7c2pzlB_
100.0 17 PDB header:sugar binding protein
Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp
8c2pk3B_
100.0 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase
9d1db3a_
100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
10c2q1wC_
100.0 17 PDB header:sugar binding protein
Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+
11c2ydyA_
100.0 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine adenosyltransferase 2 subunit beta;
PDBTitle: crystal structure of human s-adenosylmethionine synthetase2 2, beta subunit in orthorhombic crystal form
12d1kewa_
100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13c2z1mC_
100.0 16 PDB header:lyase
Chain: C: PDB Molecule:gdp-d-mannose dehydratase;
PDBTitle: crystal structure of gdp-d-mannose dehydratase from aquifex aeolicus2 vf5
14d1oc2a_
100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
15c3icpA_
100.0 16 PDB header:isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of udp-galactose 4-epimerase
16d1t2aa_
100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
17c2x4gA_
100.0 12 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa
18c2yy7B_
100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-threonine dehydrogenase;
PDBTitle: crystal structure of thermolabile l-threonine dehydrogenase from2 flavobacterium frigidimaris kuc-1
19c2p5uC_
100.0 20 PDB header:isomerase
Chain: C: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad
20d2blla1
100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
21c1t2aC_
not modelled 100.0 15 PDB header:structural genomics,lyase
Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase;
PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase
22d2c5aa1
not modelled 100.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
23d1r6da_
not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
24c2ggsB_
not modelled 100.0 29 PDB header:oxidoreductase
Chain: B: PDB Molecule:273aa long hypothetical dtdp-4-dehydrorhamnose
PDBTitle: crystal structure of hypothetical dtdp-4-dehydrorhamnose2 reductase from sulfolobus tokodaii
25c1n7gB_
not modelled 100.0 16 PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.
26d1rpna_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
27d1n7ha_
not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
28d1gy8a_
not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
29d2b69a1
not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
30c2b69A_
not modelled 100.0 16 PDB header:lyase
Chain: A: PDB Molecule:udp-glucuronate decarboxylase 1;
PDBTitle: crystal structure of human udp-glucoronic acid decarboxylase
31c2hunB_
not modelled 100.0 19 PDB header:lyase
Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase;
PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3
32c3eheB_
not modelled 100.0 17 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase (gale-1);
PDBTitle: crystal structure of udp-glucose 4 epimerase (gale-1) from2 archaeoglobus fulgidus
33d1udca_
not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
34d1wvga1
not modelled 100.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
35c3enkB_
not modelled 100.0 16 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei
36c3m2pD_
not modelled 100.0 16 PDB header:isomerase
Chain: D: PDB Molecule:udp-n-acetylglucosamine 4-epimerase;
PDBTitle: the crystal structure of udp-n-acetylglucosamine 4-epimerase2 from bacillus cereus
37c3lu1C_
not modelled 100.0 15 PDB header:isomerase
Chain: C: PDB Molecule:wbgu;
PDBTitle: crystal structure analysis of wbgu: a udp-galnac 4-epimerase
38d1e6ua_
not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
39c2hrzA_
not modelled 100.0 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: the crystal structure of the nucleoside-diphosphate-sugar epimerase2 from agrobacterium tumefaciens
40c2c20D_
not modelled 100.0 19 PDB header:isomerase
Chain: D: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of udp-glucose 4-epimerase
41d1ek6a_
not modelled 100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
42d1bxka_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
43d1rkxa_
not modelled 100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
44d1sb8a_
not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
45d1orra_
not modelled 100.0 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
46c3a1nB_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:ndp-sugar epimerase;
PDBTitle: crystal structure of l-threonine dehydrogenase from2 hyperthermophilic archaeon thermoplasma volcanium
47c3gpiA_
not modelled 100.0 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus
48d1z45a2
not modelled 100.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
49c2v6gA_
not modelled 100.0 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:progesterone 5-beta-reductase;
PDBTitle: structure of progesterone 5beta-reductase from digitalis2 lanata in complex with nadp
50c2q1uA_
not modelled 100.0 14 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmf in2 complex with nad+ and udp
51c3oh8A_
not modelled 100.0 16 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate sugar epimerase (sula family);
PDBTitle: crystal structure of the nucleoside-diphosphate sugar epimerase from2 corynebacterium glutamicum. northeast structural genomics consortium3 target cgr91
52c2iodD_
not modelled 100.0 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydroflavonol 4-reductase;
PDBTitle: binding of two substrate analogue molecules to2 dihydroflavonol-4-reductase alters the functional geometry3 of the catalytic site
53c3slgB_
not modelled 100.0 14 PDB header:transferase
Chain: B: PDB Molecule:pbgp3 protein;
PDBTitle: crystal structure of pbgp3 protein from burkholderia pseudomallei
54c2x86K_
not modelled 100.0 16 PDB header:isomerase
Chain: K: PDB Molecule:adp-l-glycero-d-manno-heptose-6-epimerase;
PDBTitle: agme bound to adp-b-mannose
55d1y1pa1
not modelled 100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
56c3iusB_
not modelled 100.0 18 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized conserved protein;
PDBTitle: the structure of a functionally unknown conserved protein2 from silicibacter pomeroyi dss
57c2p4hX_
not modelled 100.0 12 PDB header:plant protein
Chain: X: PDB Molecule:vestitone reductase;
PDBTitle: crystal structure of vestitone reductase from alfalfa2 (medicago sativa l.)
58d1eq2a_
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
59c2rh8A_
not modelled 100.0 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:anthocyanidin reductase;
PDBTitle: structure of apo anthocyanidin reductase from vitis vinifera
60c2zklA_
not modelled 100.0 21 PDB header:isomerase
Chain: A: PDB Molecule:capsular polysaccharide synthesis enzyme cap5f;
PDBTitle: crystal structure of capsular polysaccharide assembling protein capf2 from staphylococcus aureus
61d1qyda_
not modelled 100.0 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
62c3c1oA_
not modelled 100.0 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:eugenol synthase;
PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages
63c2qx7A_
not modelled 100.0 14 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
64c3e48B_
not modelled 99.9 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of a nucleoside-diphosphate-sugar epimerase2 (sav0421) from staphylococcus aureus, northeast structural genomics3 consortium target zr319
65d1qyca_
not modelled 99.9 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
66c2gn9B_
not modelled 99.9 19 PDB header:lyase
Chain: B: PDB Molecule:udp-glcnac c6 dehydratase;
PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc
67d1xgka_
not modelled 99.9 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
68c2vrcD_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)
69c3i5mA_
not modelled 99.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative leucoanthocyanidin reductase 1;
PDBTitle: structure of the apo form of leucoanthocyanidin reductase from vitis2 vinifera
70c2zcuA_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg;
PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli
71c2gasA_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:isoflavone reductase;
PDBTitle: crystal structure of isoflavone reductase
72c2exxB_
not modelled 99.9 15 PDB header:unknown function
Chain: B: PDB Molecule:hscarg protein;
PDBTitle: crystal structure of hscarg from homo sapiens in complex with nadp
73c3nzoB_
not modelled 99.9 14 PDB header:lyase
Chain: B: PDB Molecule:udp-n-acetylglucosamine 4,6-dehydratase;
PDBTitle: udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri.
74c3rfxB_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:uronate dehydrogenase;
PDBTitle: crystal structure of uronate dehydrogenase from agrobacterium2 tumefaciens, y136a mutant complexed with nad
75d2q46a1
not modelled 99.9 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
76c3ay3C_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of glucuronic acid dehydrogeanse from2 chromohalobacter salexigens
77c3e8xA_
not modelled 99.8 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative nad-dependent epimerase/dehydratase;
PDBTitle: putative nad-dependent epimerase/dehydratase from bacillus halodurans.
78c3dhnA_
not modelled 99.8 14 PDB header:isomerase, lyase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310.
79c3dqpA_
not modelled 99.8 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase ylbe;
PDBTitle: crystal structure of the oxidoreductase ylbe from2 lactococcus lactis, northeast structural genomics3 consortium target kr121.
80c3h2sA_
not modelled 99.8 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative nadh-flavin reductase;
PDBTitle: crystal structure of the q03b84 protein from lactobacillus2 casei. northeast structural genomics consortium target3 lcr19.
81d1hdoa_
not modelled 99.8 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
82c3qvoA_
not modelled 99.7 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nmra family protein;
PDBTitle: structure of a rossmann-fold nad(p)-binding family protein from2 shigella flexneri.
83d2a35a1
not modelled 99.7 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
84d2bkaa1
not modelled 99.7 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
85c3r6dA_
not modelled 99.7 17 PDB header:lyase, isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of nad-dependent epimerase/dehydratase from2 veillonella parvula dsm 2008 with cz-methylated lysine
86c3ew7A_
not modelled 99.7 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lmo0794 protein;
PDBTitle: crystal structure of the lmo0794 protein from listeria2 monocytogenes. northeast structural genomics consortium3 target lmr162.
87d2fmua1
not modelled 99.6 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
88d1hyea1
not modelled 99.2 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
89d1mlda1
not modelled 99.2 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
90c3d7lG_
not modelled 99.1 14 PDB header:structural genomics, unknown function
Chain: G: PDB Molecule:lin1944 protein;
PDBTitle: the crystal structure of the protein lin1944 from listeria innocua .
91c2jahB_
not modelled 99.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:clavulanic acid dehydrogenase;
PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus
92c3l6eA_
not modelled 98.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, short-chain dehydrogenase/reductase family;
PDBTitle: crystal structure of putative short chain dehydrogenase/reductase2 family oxidoreductase from aeromonas hydrophila subsp. hydrophila3 atcc 7966
93d1ooea_
not modelled 98.9 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
94c3grkE_
not modelled 98.9 14 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
95c3ppiA_
not modelled 98.9 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium
96c2yutA_
not modelled 98.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative short-chain oxidoreductase;
PDBTitle: crystal structure of putative short-chain oxidoreductase tthb094 from2 thermus thermophilus hb8
97c3i4fD_
not modelled 98.8 12 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
98c2hlpB_
not modelled 98.8 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of the e267r mutant of a halophilic2 malate dehydrogenase in the apo form
99d2gdza1
not modelled 98.8 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
100d1ulua_
not modelled 98.8 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
101c3lylB_
not modelled 98.8 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
102c3toxG_
not modelled 98.7 11 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
103c3p19A_
not modelled 98.7 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative blue fluorescent protein;
PDBTitle: improved nadph-dependent blue fluorescent protein
104c3l77A_
not modelled 98.7 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain alcohol dehydrogenase;
PDBTitle: x-ray structure alcohol dehydrogenase from archaeon thermococcus2 sibiricus complexed with 5-hydroxy-nadp
105c3un1D_
not modelled 98.7 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:probable oxidoreductase;
PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021
106c3ioyB_
not modelled 98.7 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: structure of putative short-chain dehydrogenase (saro_0793)2 from novosphingobium aromaticivorans
107c3k31B_
not modelled 98.7 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
108d2pd4a1
not modelled 98.7 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
109d1uaya_
not modelled 98.7 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
110d2cmda1
not modelled 98.7 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
111c3ctmH_
not modelled 98.6 13 PDB header:oxidoreductase
Chain: H: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity
112c2z5lA_
not modelled 98.6 16 PDB header:transferase
Chain: A: PDB Molecule:tylactone synthase starter module and modules 1
PDBTitle: the first ketoreductase of the tylosin pks
113d1luaa1
not modelled 98.6 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
114c3gdfA_
not modelled 98.6 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable nadp-dependent mannitol dehydrogenase;
PDBTitle: crystal structure of the nadp-dependent mannitol dehydrogenase from2 cladosporium herbarum.
115c3tfoD_
not modelled 98.6 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:putative 3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl-carrier-protein)2 reductase from sinorhizobium meliloti
116c2p68A_
not modelled 98.6 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
117c2qioA_
not modelled 98.6 14 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
118c3afnC_
not modelled 98.6 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:carbonyl reductase;
PDBTitle: crystal structure of aldose reductase a1-r complexed with nadp
119d1fjha_
not modelled 98.6 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
120c2dteB_
not modelled 98.6 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0