BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (305 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q46896 Uncharacterized protein ygbT n=119 Tax=cellular ...   617   e-175
UniRef50_Q3ZZ81 CRISPR-associated protein Cas1 n=4 Tax=Bacteria ...   241   3e-62
UniRef50_D1CGD6 CRISPR-associated protein Cas1 n=7 Tax=cellular ...   236   1e-60
UniRef50_D1CAI8 CRISPR-associated protein Cas1 n=3 Tax=Bacteria ...   224   3e-57
UniRef50_D2RB04 CRISPR-associated endonuclease Cas1, ECOLI subty...   214   2e-54
UniRef50_Q2JWC7 CRISPR-associated protein Cas1 n=3 Tax=Chroococc...   211   3e-53
UniRef50_Q21QB1 CRISPR-associated protein Cas1 n=1 Tax=Rhodofera...   206   9e-52
UniRef50_Q03C58 CRISPR-associated protein n=3 Tax=Lactobacillus ...   200   6e-50
UniRef50_D1NTI3 CRISPR-associated protein Cas1 n=10 Tax=Bacteria...   199   7e-50
UniRef50_A8M406 CRISPR-associated protein Cas1 n=5 Tax=Actinomyc...   199   1e-49
UniRef50_C7LYW4 CRISPR-associated protein Cas1 n=1 Tax=Acidimicr...   194   3e-48
UniRef50_C7MTM5 CRISPR-associated protein, Cas1 family n=6 Tax=A...   191   3e-47
UniRef50_D1A5U2 CRISPR-associated protein Cas1 n=3 Tax=Actinomyc...   187   4e-46
UniRef50_B1VIX8 CRISPR-associated protein n=6 Tax=Corynebacteriu...   185   2e-45
UniRef50_C7QEM2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria ...   183   8e-45
UniRef50_B4V4P5 Crispr-associated protein cas1 n=4 Tax=Streptomy...   178   2e-43
UniRef50_C7MTL6 CRISPR-associated protein, Cas1 family n=4 Tax=A...   177   5e-43
UniRef50_C4X9I5 CRISPR-associated Cas1 family protein n=12 Tax=B...   174   2e-42
UniRef50_C2BS02 CRISPR-associated protein n=1 Tax=Mobiluncus cur...   165   1e-39
UniRef50_C9M9R9 CRISPR-associated protein Cas1 n=1 Tax=Jonquetel...   164   4e-39
UniRef50_C1YVP5 CRISPR-associated protein Cas1 n=1 Tax=Nocardiop...   162   9e-39
UniRef50_Q0AA34 CRISPR-associated protein Cas1 n=11 Tax=Bacteria...   146   9e-34
UniRef50_Q47PJ6 CRISPR-associated protein, Cas1 family n=4 Tax=A...   143   6e-33
UniRef50_A3LCN8 Putative uncharacterized protein n=1 Tax=Pseudom...   138   2e-31
UniRef50_B6IWM1 CRISPR-associated protein Cas1, putative n=1 Tax...   138   3e-31
UniRef50_C2KP50 CRISPR-associated Cas1 family protein n=5 Tax=Ac...   109   1e-22
UniRef50_Q3J7J6 CRISPR-associated protein, Cas1 family n=2 Tax=N...    75   3e-12
UniRef50_C6CA70 CRISPR-associated protein Cas1 n=56 Tax=Bacteria...    59   2e-07
UniRef50_D1BQ37 CRISPR-associated protein Cas1 n=1 Tax=Veillonel...    57   1e-06
UniRef50_C8Q0H7 CRISPR-associated protein Cas1 n=6 Tax=Proteobac...    48   5e-04
UniRef50_D2QT50 CRISPR-associated protein Cas1 n=1 Tax=Spirosoma...    47   0.001
UniRef50_C8W2P4 CRISPR-associated protein Cas1 n=1 Tax=Desulfoto...    45   0.002
UniRef50_C1XN81 CRISPR-associated protein Cas1 n=2 Tax=Meiotherm...    45   0.003
UniRef50_B8CYA1 CRISPR-associated protein Cas1 n=2 Tax=cellular ...    44   0.006
UniRef50_C0QHV1 Putative CRISPR-associated protein (Uncharacteri...    44   0.009
UniRef50_Q96X75 Putative uncharacterized protein ST2634 n=1 Tax=...    44   0.010
UniRef50_B8D4S7 CRISPR-associated protein Cas1 n=1 Tax=Desulfuro...    43   0.012
UniRef50_A1ZHZ5 Crispr-associated protein Cas1 n=1 Tax=Microscil...    43   0.014
UniRef50_A3XI90 Putative uncharacterized protein n=1 Tax=Leeuwen...    42   0.032
UniRef50_Q2FL78 CRISPR-associated protein, Cas1 family n=1 Tax=M...    42   0.036

>UniRef50_Q46896 Uncharacterized protein ygbT n=119 Tax=cellular organisms
           RepID=YGBT_ECOLI
          Length = 305

 Score =  617 bits (1592), Expect = e-175,   Method: Compositional matrix adjust.
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60
           MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV
Sbjct: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60

Query: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120
           SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF
Sbjct: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120

Query: 121 ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180
           ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI
Sbjct: 121 ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP 240
           SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP
Sbjct: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP 240

Query: 241 GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA 300
           GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA
Sbjct: 241 GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA 300

Query: 301 GHRSS 305
           GHRSS
Sbjct: 301 GHRSS 305


>UniRef50_Q3ZZ81 CRISPR-associated protein Cas1 n=4 Tax=Bacteria RepID=Q3ZZ81_DEHSC
          Length = 309

 Score =  241 bits (614), Expect = 3e-62,   Method: Compositional matrix adjust.
 Identities = 118/280 (42%), Positives = 180/280 (64%), Gaps = 2/280 (0%)

Query: 6   LNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           L+ +P  +DR S ++L+ G++DV +   +   +      +P+  +  +ML PG+ V+HAA
Sbjct: 4   LHELPRFRDRWSYLYLEMGRLDV-EADSLGFHQGDTVVPVPIDQLGVVMLGPGSTVTHAA 62

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           ++  +Q   L+ W G+ GVR+YA+   G   + +L+ QA+L  D++ RL+V  +M+  RF
Sbjct: 63  IKSLSQNNCLIAWTGQDGVRLYAASIGGTYSARRLIRQARLVSDDEKRLEVAWRMYRFRF 122

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            E  P   S+E +RG+EG RVR  YA  +++YGV W GR YD KDW KGD IN+ +SAA 
Sbjct: 123 NEVIPPVVSLESIRGMEGIRVRRAYAKASQEYGVEWKGRHYDQKDWSKGDPINRALSAAN 182

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           +CLYG+  A IL+AGY+ A+GFVHTGK LSFVYD+AD+ K +  +P AF++A  NP + +
Sbjct: 183 ACLYGICHAGILSAGYSSALGFVHTGKMLSFVYDVADLYKTELTIPVAFKVAAANPTDLE 242

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPE 284
           R+VR+ CR+ F   K L +L+  I +VL   +    +P E
Sbjct: 243 RQVRIECREAFYEFKLLERLLTDIAEVLGVSDDIGESPDE 282


>UniRef50_D1CGD6 CRISPR-associated protein Cas1 n=7 Tax=cellular organisms
           RepID=D1CGD6_THET1
          Length = 324

 Score =  236 bits (601), Expect = 1e-60,   Method: Compositional matrix adjust.
 Identities = 120/278 (43%), Positives = 170/278 (61%), Gaps = 4/278 (1%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           + D  S +++++ +ID    A  L D TG +T +P  S++ +ML PGT ++HAA++  A 
Sbjct: 12  VSDSWSYLYVEHCRIDQDARAISLHDATG-KTMVPCASLSLLMLGPGTSITHAAIQTLAD 70

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            G L+ WVGE GVR YA G      +   L QA L  D +L L+VVR+M+E+RF  P   
Sbjct: 71  NGCLVAWVGEEGVRFYAQGMGETRSATNTLRQAMLWSDPELHLQVVRRMYEIRFRHPINP 130

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
             S++Q+RG+EG+RVR  Y  L+++ GV W GR Y  K W   D IN+ ISAA SCLYGV
Sbjct: 131 NTSLKQIRGMEGARVRGAYLQLSRETGVEWKGRDYSSKSWHSNDAINRAISAANSCLYGV 190

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
             AAI++AGY+ A+GF+HTGK LSFVYD+AD+ K +  +P AF          +  VR  
Sbjct: 191 CHAAIVSAGYSTALGFIHTGKMLSFVYDVADLYKTEISMPAAFYAVAEGGASLESRVRRK 250

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQP 288
           CRDI R ++ LA+++  I+ VL    +  P P +   P
Sbjct: 251 CRDILRETRLLARIVEDIDTVL---NVDSPIPHKYQNP 285


>UniRef50_D1CAI8 CRISPR-associated protein Cas1 n=3 Tax=Bacteria RepID=D1CAI8_SPHTD
          Length = 314

 Score =  224 bits (570), Expect = 3e-57,   Method: Compositional matrix adjust.
 Identities = 117/288 (40%), Positives = 175/288 (60%), Gaps = 6/288 (2%)

Query: 4   LPLNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           + L+ +P ++D  S +++++ +I+    A  + D  G+   +P  S+  +ML PGT +SH
Sbjct: 1   MDLHILPKVRDSWSYLYVEHARIEQEAKAIAIHDAVGM-VPVPCASLGILMLGPGTSISH 59

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
           AA+R  A+ G L++W GE GVR YA G      +  L+ QA+L  D  LRL+VV +M+++
Sbjct: 60  AAIRTLAENGCLVLWTGEEGVRFYAQGLGETRSARNLMRQARLWADPALRLRVVFRMYQM 119

Query: 123 RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISA 182
           RF EP P   +++Q+RG+EG+RVR  YA  +++ GV W GR +  ++W   D IN+ +S 
Sbjct: 120 RFSEPLPPDLTLQQIRGMEGARVRDAYARASRETGVPWRGRSFQRRNWSATDPINRALSC 179

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           A SCLYG+  AAI++ GY+P +GF+HTGK LSFVYDIAD+ K    +P AF +      +
Sbjct: 180 ANSCLYGICHAAIVSLGYSPGLGFIHTGKMLSFVYDIADLYKATVTIPLAFRVVAEGTHD 239

Query: 243 PDREVRLACRDIFRSSKTLAKLIPLIEDVL----AAGEIQPPAPPEDA 286
            +  VR ACRD F + + L  +   IE VL    A G    P   EDA
Sbjct: 240 LEGRVRRACRDAFVAHRLLGTIATDIEHVLDISDADGGADEPDFDEDA 287


>UniRef50_D2RB04 CRISPR-associated endonuclease Cas1, ECOLI subtype n=3 Tax=Bacteria
           RepID=D2RB04_GARVA
          Length = 313

 Score =  214 bits (546), Expect = 2e-54,   Method: Compositional matrix adjust.
 Identities = 105/264 (39%), Positives = 158/264 (59%), Gaps = 3/264 (1%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           + DRVS I++++ +I+ +D A  + D  G    +P   +  ++L PGT ++H A+ L   
Sbjct: 18  ISDRVSFIYVEHAKINRLDSAVTVFDANGT-IRVPAAMIGVLLLGPGTEITHRAMELLGD 76

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
           VG  +VWVGE GVR YA G+     S  L  Q+KL  +   RL V RKM+++RF     +
Sbjct: 77  VGASIVWVGEHGVRNYAHGRALSRSSRLLEKQSKLVTNSRSRLNVARKMYQMRFPNENVS 136

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
             +++QLRG EG+RVR  Y  ++ +Y V WNGR Y   D+E G  +N+ +S    CLYG+
Sbjct: 137 SYTLQQLRGREGARVRHLYREMSNKYNVQWNGRDYKVNDFESGTVVNKALSVGNVCLYGL 196

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDRE--VR 248
             + I A G AP +GFVHTG  LS VYDIAD+ K +  +P +FEIA R   + D E  +R
Sbjct: 197 VHSIISALGLAPGLGFVHTGHDLSLVYDIADLYKAELTIPASFEIAARCESDDDIEQLMR 256

Query: 249 LACRDIFRSSKTLAKLIPLIEDVL 272
           L  RD F +   +++++  I+++L
Sbjct: 257 LKMRDCFANCNIMSRIVNDIQNLL 280


>UniRef50_Q2JWC7 CRISPR-associated protein Cas1 n=3 Tax=Chroococcales
           RepID=Q2JWC7_SYNJA
          Length = 315

 Score =  211 bits (536), Expect = 3e-53,   Method: Compositional matrix adjust.
 Identities = 112/299 (37%), Positives = 175/299 (58%), Gaps = 6/299 (2%)

Query: 6   LNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           L  IP ++D +S ++++  +I+    A  ++ + G R  IP  S+  +ML PGT ++HAA
Sbjct: 10  LRSIPKVRDSISFVYVERCRIEQDAKAIAVLQEDG-RYIIPCASLTTLMLGPGTAITHAA 68

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           ++  A     + WVGE G+R YASG    +  ++L +QAKL  D    ++VVR+M+  RF
Sbjct: 69  IKNLADGLCSVQWVGEDGLRFYASGSHPSSSVERLYHQAKLWADPVQHMEVVRRMYSFRF 128

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            EP     ++EQ+RG+EG RVR  Y+ L+K+ GV W GR Y  K+WE  D +N+ +S A 
Sbjct: 129 PEPLKEGLTLEQIRGLEGVRVRTVYSRLSKETGVNWKGRSYKLKEWECADPVNRALSVAN 188

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           +CLY V +AA+ A GY+ A+GF+H GKPLSFVYD+AD+ K +  +P AF+ A       +
Sbjct: 189 TCLYAVCQAALNAVGYSTALGFIHIGKPLSFVYDVADLYKTEITIPVAFKAAAELMPNFE 248

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVSLGD 299
              R  CR+ F   + + ++I  ++ +L     Q  + P     D +  A+   VS G+
Sbjct: 249 SRTRQLCREKFVEHRLMQRIIDDVDAILGFRATQEESSPVGSLWDNEKGAVEGGVSYGE 307


>UniRef50_Q21QB1 CRISPR-associated protein Cas1 n=1 Tax=Rhodoferax ferrireducens
           T118 RepID=Q21QB1_RHOFD
          Length = 277

 Score =  206 bits (524), Expect = 9e-52,   Method: Compositional matrix adjust.
 Identities = 105/261 (40%), Positives = 154/261 (59%), Gaps = 9/261 (3%)

Query: 12  KDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           K+R+  +FL+ G + V DG  +L+ +      IP   V+C+M+EPG  V+H A++L  + 
Sbjct: 18  KNRIPYLFLEKGILRV-DGHCLLLCQAESAIEIPGSMVSCLMIEPGVSVTHEAMKLCGEN 76

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPAR 131
           GTLL+WVGE G R YA+       + ++L QA +  ++  R+    +++ L F +  P  
Sbjct: 77  GTLLMWVGEGGTRFYAAAH-AHQDASRVLRQAAIHTNQRERIAAASRLYGLMFDDHMPPS 135

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
            ++E+LRG+EGSRV+  Y  LA + G+ W GR       E+   +N  I  ATSCLY + 
Sbjct: 136 FTIEKLRGLEGSRVKEIYVNLADKLGMVWQGR-------EEKSALNTSIGFATSCLYALC 188

Query: 192 EAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLAC 251
           E AILAAGY P IG VH+G P S V+D+AD +KF TVVP AFEIA  +P   +  VR  C
Sbjct: 189 EVAILAAGYHPGIGVVHSGNPRSLVFDLADTVKFKTVVPLAFEIAATSPSNLNMAVRHGC 248

Query: 252 RDIFRSSKTLAKLIPLIEDVL 272
           RD+F        L+  +E++ 
Sbjct: 249 RDLFSRESMFETLLGHLENIF 269


>UniRef50_Q03C58 CRISPR-associated protein n=3 Tax=Lactobacillus RepID=Q03C58_LACC3
          Length = 315

 Score =  200 bits (508), Expect = 6e-50,   Method: Compositional matrix adjust.
 Identities = 105/258 (40%), Positives = 161/258 (62%), Gaps = 5/258 (1%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           +++RV+ ++L++ +I+  D A V+ID TG    IP   ++ +ML PG  V+H A+ L   
Sbjct: 16  VRERVTFLYLEHAKINRQDSAIVVID-TGGTVAIPAALISVLMLGPGVDVTHRAMELMGD 74

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            G  +VWVGE GVR YA G+     S  L+ QAKL  +  LR+ V R+M+++RF +   +
Sbjct: 75  AGMSVVWVGERGVRQYAPGRALTHSSALLVAQAKLVSNNRLRVGVARQMYQMRFPDDDVS 134

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
             S+++LRG EG+RVR  Y   +++ GV W  R YDP++++ G  INQ ++AA + LYG+
Sbjct: 135 TLSMQELRGKEGARVRRIYREESRRTGVEWTHREYDPENYQSGSIINQALTAAHAALYGL 194

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD---REV 247
           + + I+A G +P +GFVHTG  LSFVYD AD+ K +  +P AF +A  N  E D   +  
Sbjct: 195 SYSVIVALGASPGLGFVHTGHDLSFVYDFADLYKAEVTIPIAFTVA-ANATEQDDIGQLT 253

Query: 248 RLACRDIFRSSKTLAKLI 265
           RLA RD F   K + +++
Sbjct: 254 RLAVRDAFVDGKLMIRMV 271


>UniRef50_D1NTI3 CRISPR-associated protein Cas1 n=10 Tax=Bacteria RepID=D1NTI3_9BIFI
          Length = 366

 Score =  199 bits (507), Expect = 7e-50,   Method: Compositional matrix adjust.
 Identities = 102/267 (38%), Positives = 155/267 (58%), Gaps = 1/267 (0%)

Query: 12  KDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +DR++ ++ ++  ++  + A  + D  G+R HIP  +++ +ML PGT V+H A+ +    
Sbjct: 37  EDRLTFLYFEHCVVNRDNNAITVTDDRGVR-HIPAAALSVLMLGPGTSVTHQAMMVIGDN 95

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPAR 131
           G  ++WVGE GVR Y SG+P    S+ L  QA+L  +   RL V R M+ +RF     + 
Sbjct: 96  GATVIWVGERGVRTYCSGKPLTHSSNLLQKQAQLVTNMRKRLSVARAMYAMRFPHEDVSN 155

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
            +++QLRG EG+RVR  Y   +KQ GV W  R Y P+D+   D INQ +SAA  CLYG+ 
Sbjct: 156 LTMQQLRGREGARVRRVYRHWSKQTGVRWERRDYRPEDFADSDRINQALSAANICLYGIA 215

Query: 192 EAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLAC 251
            A I+A G +P +GFVHTG  LSFVYD+AD+ K +  +P AF+ A     +    VR A 
Sbjct: 216 HAVIVALGCSPGLGFVHTGHELSFVYDMADLYKAELSIPVAFKTAATEVDDIGGAVRRAM 275

Query: 252 RDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           RD       + +++  I  +  A + +
Sbjct: 276 RDAMYDLSIMPRMVKDIHHLFDAADAE 302


>UniRef50_A8M406 CRISPR-associated protein Cas1 n=5 Tax=Actinomycetales
           RepID=A8M406_SALAI
          Length = 322

 Score =  199 bits (505), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 114/286 (39%), Positives = 160/286 (55%), Gaps = 5/286 (1%)

Query: 12  KDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +DR+S ++L+   I     A    D+ GI  HIP  ++  +ML PGT ++  A+ L A  
Sbjct: 18  QDRISFVYLERCVIHRDSNAITATDEKGI-VHIPAATLGVLMLGPGTSITQQAMMLIADN 76

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPAR 131
           G  +VW+GE GVR YA G+P    S  L+ QA      D RL+V R M+ +RF       
Sbjct: 77  GATVVWIGEHGVRYYAHGRPLARSSRLLVAQAAAVSHRDRRLRVARAMYRMRFPGEDTTN 136

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
            +++QLRG EG+RVR  Y   A++ GV+WN R YDP D+   D +NQ +SAA +CLYG+ 
Sbjct: 137 LTMQQLRGKEGARVRRCYRENAQRTGVSWNSREYDPDDFTGSDPVNQALSAAHACLYGIV 196

Query: 192 EAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLAC 251
            A ++A G +P +GFVHTG   SFVYDIAD+ K D  +P AF+IA     +   + R A 
Sbjct: 197 HAVVVAVGASPGLGFVHTGHDRSFVYDIADLYKADVTIPVAFDIAAAESTDIGADTRRAV 256

Query: 252 RDIFRSSKTLAKLIPLIEDVL----AAGEIQPPAPPEDAQPVAIPL 293
           RD   +   L + +  I  +L    AAG I      E+A   A+ L
Sbjct: 257 RDRVHNGALLGRCVQDIRRLLLTDSAAGPINEEEFDEEADNDAVRL 302


>UniRef50_C7LYW4 CRISPR-associated protein Cas1 n=1 Tax=Acidimicrobium ferrooxidans
           DSM 10331 RepID=C7LYW4_ACIFD
          Length = 314

 Score =  194 bits (493), Expect = 3e-48,   Method: Compositional matrix adjust.
 Identities = 99/265 (37%), Positives = 159/265 (60%), Gaps = 3/265 (1%)

Query: 10  PLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
           P+  R S ++L++  +     A V + ++G  T++P  +V  ++L PGTR++H A+ L  
Sbjct: 20  PVSRRSSFVYLEHCVVHRDANAVVSVTESGT-TYLPAAAVGTLLLGPGTRITHQAMLLLG 78

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKLLY-QAKLALDEDLRLKVVRKMFELRFGEPA 128
           + G ++ WVGE   R+YA   P   +S + L  QA+L  +   RL+V R+M+++RF    
Sbjct: 79  ESGVVVCWVGEGDTRLYAWA-PSLFQSTRFLEAQARLVSNRQDRLRVARQMYQMRFPGED 137

Query: 129 PARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLY 188
            ++ ++++LRG+EG+R+R TY  LA  +G+ W+GR YDP +   GD +N+ +S A S LY
Sbjct: 138 VSKATMQRLRGMEGARIRRTYRHLASAFGIDWHGRHYDPNNSSAGDDVNRALSIANSVLY 197

Query: 189 GVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVR 248
           GV   AI+A G +P +GFVHTG  LSFVYD+AD+ K +  +P AFE A +  G    +VR
Sbjct: 198 GVVHTAIVALGCSPGLGFVHTGHSLSFVYDVADLYKVELAIPVAFEAAAQRTGSLSSQVR 257

Query: 249 LACRDIFRSSKTLAKLIPLIEDVLA 273
              R+    +  L + +  I  +L 
Sbjct: 258 RTMRERIHEAHLLERAVDDIRLLLG 282


>UniRef50_C7MTM5 CRISPR-associated protein, Cas1 family n=6 Tax=Actinomycetales
           RepID=C7MTM5_SACVD
          Length = 342

 Score =  191 bits (485), Expect = 3e-47,   Method: Compositional matrix adjust.
 Identities = 110/274 (40%), Positives = 163/274 (59%), Gaps = 5/274 (1%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           L DRVS ++++   +D  + A  +I++      +P   VA ++L PGTRV+H A++L A 
Sbjct: 18  LTDRVSSVYIERSHLDRAENAIAIINRRET-VRLPAALVAVVLLGPGTRVTHGAMQLLAD 76

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLY-QAKLALDEDLRLKVVRKMFELRFGEPAP 129
            GT + WVGE GVR+YA+G  G +R   LL  QA L      RL+V R M+ +RF     
Sbjct: 77  SGTAVCWVGEQGVRMYAAGL-GPSRGAALLQRQAYLVSRTTTRLEVARAMYAMRFPGEDV 135

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD-WEKGDTINQCISAATSCLY 188
           +  +++QLRG EG+RVR  Y   A+Q+GV WNGR Y   D +  GD +N+ +SAA + LY
Sbjct: 136 STLTMQQLRGREGARVRKVYRQQARQHGVPWNGRAYKAGDAFAVGDDLNRLLSAANAALY 195

Query: 189 GVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVR 248
           G+  A I+  G +P +GF+HTG   SFV DIAD+ K +  +P AF++A R   E +R+ R
Sbjct: 196 GICHAVIVGLGASPGLGFIHTGSATSFVMDIADLYKAEYTIPLAFQLAARGLLE-ERDAR 254

Query: 249 LACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAP 282
            A RD    +  L ++I  ++ +LA   +  P P
Sbjct: 255 TALRDRIAGTGLLPRIIKDVKTLLAPEGVDLPDP 288


>UniRef50_D1A5U2 CRISPR-associated protein Cas1 n=3 Tax=Actinomycetales
           RepID=D1A5U2_THECD
          Length = 315

 Score =  187 bits (475), Expect = 4e-46,   Method: Compositional matrix adjust.
 Identities = 105/297 (35%), Positives = 155/297 (52%), Gaps = 7/297 (2%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + DR+S I+L+   +   D A    D  GI THIP  ++ C++L PGTRV+H A
Sbjct: 12  PRELTRMSDRISFIYLERCTLHREDNAITAEDADGI-THIPSATIGCLLLGPGTRVTHQA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + +    G  +VWVGE GVR Y+ G+     S  +  QA    +   RL+V R M+ +RF
Sbjct: 71  MSVLGDSGAGVVWVGEQGVRFYSGGRSLTRSSALVEAQAIKWANRRTRLEVARAMYRMRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +  PA  + ++L G EG RV+  Y   A +YG+TW GR Y P D+   D +NQ ++AA 
Sbjct: 131 PDEDPAGLTRQELLGREGRRVKERYRQEAAKYGITWKGRHYIPGDFGSSDPVNQAVTAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C+YG+ +  + A G +P +GF+H+G  L+FV DIAD+ K +  +P AF     +P +  
Sbjct: 191 QCMYGIAQTTVAALGCSPGLGFIHSGHELAFVLDIADLYKTEFALPIAFRTVAESPEDVG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAG 301
              R A RD       L + +  I+ +L       P  P+D     I      GD G
Sbjct: 251 SRTRRAIRDEVNRVGLLRRCVDDIKSLLL------PDVPDDPLNSDIDQVTLQGDHG 301


>UniRef50_B1VIX8 CRISPR-associated protein n=6 Tax=Corynebacterium
           RepID=B1VIX8_CORU7
          Length = 312

 Score =  185 bits (470), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 93/269 (34%), Positives = 154/269 (57%), Gaps = 1/269 (0%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           + DR+S ++++   +     A  + D+ G+  H+P   +A ++L  GTR+++AA+ L   
Sbjct: 17  MGDRISFLYVERAVVSRDGNALTITDQRGV-AHVPATQLAVLLLGTGTRITNAAMALLGD 75

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            G   VWVGE GVR YA G+P    S     QA++  ++  RL+  R+M+ LRF     +
Sbjct: 76  CGVSTVWVGERGVRYYAHGRPPAKSSRLAELQARVVTNQRKRLECARRMYGLRFPGEDVS 135

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
           + ++ QLRG EG+R++  YA  AK+ GV WN RRYDP D++  D INQ ++  ++ LYG+
Sbjct: 136 KLTMAQLRGREGARMKRLYAAEAKRTGVAWNRRRYDPNDYDSSDPINQALTTGSAALYGI 195

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
             A I+  G+ PA+G +HTG   SFVYD+AD+ K +  +P AF        +    VR  
Sbjct: 196 AHAVIVGLGFVPALGVIHTGTDRSFVYDVADLYKAEVSIPAAFNAVASGTEDVGPMVRRL 255

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
            RD     + + +++  ++ V++  + +P
Sbjct: 256 VRDAVVEQRLMPRMVRDLKFVMSVPDDEP 284


>UniRef50_C7QEM2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria RepID=C7QEM2_CATAD
          Length = 323

 Score =  183 bits (464), Expect = 8e-45,   Method: Compositional matrix adjust.
 Identities = 94/269 (34%), Positives = 150/269 (55%), Gaps = 1/269 (0%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           + DRVS ++L+   +     A    D  GI THIP  ++  ++L PGTR++H A+ +   
Sbjct: 18  IADRVSFVYLERCTVHRDANAITAQDADGI-THIPSATIGTLLLGPGTRITHQAMAVLGD 76

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            G  + WVGE G R YA+ +     S  +  QA L  +   RL + R M+ +RF +  P+
Sbjct: 77  CGANVAWVGEHGARFYAAARSLNRSSALVEAQATLWANRRTRLDIARAMYRMRFPDEDPS 136

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
               +QL G+EG R++  Y   +++ GV W+GR+Y P ++  GD INQ I+AA  C+YGV
Sbjct: 137 GFMRQQLLGMEGRRLKDCYRQQSQRTGVPWHGRQYTPGNFNAGDAINQAITAAAQCMYGV 196

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
               I A G +P +GF+H+G  LSFV DIAD+ K +  +P AF+ A  +  +     R A
Sbjct: 197 AHTIITALGCSPGLGFIHSGHELSFVMDIADLYKTEIGIPVAFDTAAEDSTDIGPRTRRA 256

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
            R+  R+++ L + +  ++ +L     +P
Sbjct: 257 LREQIRTTRLLERCVDDVKALLTTPNNEP 285


>UniRef50_B4V4P5 Crispr-associated protein cas1 n=4 Tax=Streptomyces
           RepID=B4V4P5_9ACTO
          Length = 315

 Score =  178 bits (451), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 99/278 (35%), Positives = 149/278 (53%), Gaps = 6/278 (2%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + +R+S ++L+   +     A    D  G  THIP  ++  ++L PGTR++H A
Sbjct: 12  PRELTRVAERISFVYLERCVVHRDANAITAEDADGT-THIPSATIGTLLLGPGTRITHQA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + + A+ G  + WVGE GVR YA G+     S  +  QA L  +   RL+V R M+ LRF
Sbjct: 71  MSVLAESGAAVAWVGEQGVRYYAGGRALSRSSALVEAQATLWANRRTRLEVARAMYRLRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +  P+  +  +L G EG RV+  Y   A + GV W GR Y P D+  GD  NQ ++AA 
Sbjct: 131 PDEDPSGLTRRELLGHEGYRVKECYRHQADRTGVPWRGRHYVPGDFTAGDAPNQAVTAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C+YG+  A + A G A  +GFVH+G  LSFV D+AD+ K +  +P AF++A  +  +  
Sbjct: 191 QCMYGIAHAVVAALGCATGLGFVHSGHELSFVLDVADLYKTEIGIPVAFDVAAESTEDIG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAP 282
              R A RD    ++ L + +  I+ +L     QP  P
Sbjct: 251 SRTRRALRDAVNKNRLLDRCVNDIKLLL-----QPEGP 283


>UniRef50_C7MTL6 CRISPR-associated protein, Cas1 family n=4 Tax=Actinomycetales
           RepID=C7MTL6_SACVD
          Length = 328

 Score =  177 bits (448), Expect = 5e-43,   Method: Compositional matrix adjust.
 Identities = 90/257 (35%), Positives = 146/257 (56%), Gaps = 8/257 (3%)

Query: 41  RTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLL 100
           R ++PV +++CI+   GT V+  A+   A+  T ++W G  GVR+Y+        ++ L 
Sbjct: 57  RVYLPVAAISCILFGTGTSVTQPAMATCARHNTTVLWTGSGGVRMYSGSLAPNLTTEWLE 116

Query: 101 YQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW 160
            Q +   D+  RL V  +M+ +RFG   PA  S+  LRG+EG R++A Y  LA ++G+  
Sbjct: 117 RQVRAWADDSTRLAVAARMYSMRFGAEVPAGTSLNTLRGLEGQRMKALYRSLADRHGLRG 176

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIA 220
             R YDP +W + + +NQ +SAA + LYG   +A+LA G +PA+GF+H+GK  SFVYD+A
Sbjct: 177 FKRNYDPANWGEQNPVNQALSAANTALYGAVHSALLALGCSPALGFIHSGKQHSFVYDVA 236

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
           D+ K    +P AF + +    +PDREVR+  R  F   + + +++  ++ +L       P
Sbjct: 237 DLYKAKHTIPLAFALHK--SAQPDREVRIRMRQDFHLYRLMPRIVRDVQRLL------DP 288

Query: 281 APPEDAQPVAIPLPVSL 297
           +  +D      P  V L
Sbjct: 289 SIAQDHDETGEPEEVEL 305


>UniRef50_C4X9I5 CRISPR-associated Cas1 family protein n=12 Tax=Bacteria
           RepID=C4X9I5_KLEPN
          Length = 294

 Score =  174 bits (442), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 91/258 (35%), Positives = 142/258 (55%), Gaps = 3/258 (1%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           +KD+   ++L+ G++++ D +   +D  G    +PV ++  ++L PGT V+H A++ A  
Sbjct: 22  VKDKYPFLYLERGRLEIDDSSVKWVDADGNVVPLPVATINTLLLGPGTTVTHEAIKTATA 81

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
               + WVGE  +  YA+G    A +  L  Q  LA D    LKV R MF  RF +    
Sbjct: 82  ANCAVCWVGEDSLLFYAAGFLPTADTRNLKAQMALACDASSTLKVARAMFAKRFPDADLE 141

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
            +S+  + G+EGSRVRA Y   A++YGV W GR++ P  +E  D  NQ +++  + LYG+
Sbjct: 142 GKSLNSMMGMEGSRVRALYQQKAQEYGVGWKGRQFTPGKFELSDLTNQVLTSTNAALYGI 201

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
             + + A GY+P IGF+H+G PL FVYD+AD+ K    +  AF ++R   G  D+     
Sbjct: 202 LCSVVHAMGYSPHIGFIHSGSPLPFVYDLADLYKERLCIDLAFSLSREMAGRYDKH---K 258

Query: 251 CRDIFRSSKTLAKLIPLI 268
             + FR       L+ LI
Sbjct: 259 VSEAFRKRVIALDLLNLI 276


>UniRef50_C2BS02 CRISPR-associated protein n=1 Tax=Mobiluncus curtisii ATCC 43063
           RepID=C2BS02_9ACTO
          Length = 314

 Score =  165 bits (418), Expect = 1e-39,   Method: Compositional matrix adjust.
 Identities = 87/262 (33%), Positives = 148/262 (56%), Gaps = 1/262 (0%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           ++DR+S ++++   ++    A  + D  GI  HIP   V  ++L PGT+V++AA+ L   
Sbjct: 18  MEDRLSFLYVERAILNREGNALTIQDSRGI-AHIPATQVGVVLLGPGTKVTYAAMALLGD 76

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            G   VWVGE GVR YA G+P    S      A+L  ++  RL+  R+M+ +RF     +
Sbjct: 77  AGCSAVWVGEKGVRYYAHGRPAAKTSRMAEAHARLWANQRSRLRCARRMYSMRFPGEDVS 136

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
              + QLRG EG+R++  YA  +++ GV W  R YDP D+  GD IN  ++   + LYG+
Sbjct: 137 NLPLSQLRGREGARMKRIYAEQSRRTGVPWTRRSYDPNDFGAGDPINCALTEGAAALYGI 196

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
             A ++  G+ P++G +H+G   +FVYD+AD+ K +  +P AFE    +    +  VR  
Sbjct: 197 AHAVVVGLGFIPSLGIIHSGTDRAFVYDVADLYKAEISIPAAFEAVAASAEGDELNVRKR 256

Query: 251 CRDIFRSSKTLAKLIPLIEDVL 272
            RD   +++ + +++  ++ V+
Sbjct: 257 IRDKVVTTRLMQRMVRDLQYVM 278


>UniRef50_C9M9R9 CRISPR-associated protein Cas1 n=1 Tax=Jonquetella anthropi E3_33
           E1 RepID=C9M9R9_9BACT
          Length = 281

 Score =  164 bits (415), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 99/270 (36%), Positives = 151/270 (55%), Gaps = 12/270 (4%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTH-----IPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           M++L+ G + V DG    +   G         IP  +V+ I+LEPGT ++H   RL  Q 
Sbjct: 1   MLWLERGNLFVKDGTLRFVSAGGGSLEKGTYDIPYQNVSMIVLEPGTTITHDVFRLMGQQ 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPAR 131
           GT L+ VG+ GVR Y +   G  RS     Q +L  +   RL+V   M+ +RFGE  P R
Sbjct: 61  GTGLIAVGDKGVRCYTAPPLGPDRSALARRQVELWANPQTRLQVALAMYAIRFGEELPTR 120

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
           + +E LRGIEG+R+R +Y++LAK YG+TW  RR++ K   K D IN  ++ A S +YG  
Sbjct: 121 K-IEDLRGIEGARLRKSYSILAKFYGLTWTLRRFNRKQPNKTDDINAAVNHAASAMYGAA 179

Query: 192 EAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP----DREV 247
           + A+ A    P +GFVH     +F  DIAD+ + +  +P AF        EP    +R V
Sbjct: 180 DIAVAAVSAIPQLGFVHAKSCRAFALDIADLYRTEITLPAAFRGLASYLEEPGMDLERHV 239

Query: 248 R-LACRDIFRSSKTLAKLIPLIEDVLAAGE 276
           R L  ++++R  K ++K+I  I++++  G+
Sbjct: 240 RKLIGQELYR-QKVISKMIDQIKELILHGQ 268


>UniRef50_C1YVP5 CRISPR-associated protein Cas1 n=1 Tax=Nocardiopsis dassonvillei
           subsp. dassonvillei DSM 43111 RepID=C1YVP5_NOCDA
          Length = 327

 Score =  162 bits (411), Expect = 9e-39,   Method: Compositional matrix adjust.
 Identities = 101/288 (35%), Positives = 148/288 (51%), Gaps = 4/288 (1%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + +R+S ++L+   +     A    D  G R ++P  ++  ++L PGT V+H+A
Sbjct: 12  PRELTRVGERLSFLYLERCVVHRDSNAITAEDGDGTR-YLPSATIGTLLLGPGTNVTHSA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLY-QAKLALDEDLRLKVVRKMFELR 123
           + L  + G  +VWVGE GVR YA+G+    RS +L+  QA    +   RL V R M+ +R
Sbjct: 71  MSLLGECGATVVWVGEHGVRYYAAGRAL-TRSSRLVEAQATAWANRRSRLDVARAMYRMR 129

Query: 124 FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
           F +      S + L G EG RV+A Y   A + GVTW GRRY P D +  D  N+ I+AA
Sbjct: 130 FPDLDVEALSRQALLGKEGDRVKACYREQAARTGVTWRGRRYVPGDHDVSDPPNKAITAA 189

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
             C YGV  A   A G +P +GFVH+G    FV D+AD+ K +  +P AF+ A +   + 
Sbjct: 190 AQCFYGVAHAVTAALGCSPGLGFVHSGHERGFVMDVADLYKVEIGIPVAFDAAAQGDEDV 249

Query: 244 DREVRLACRDIFRSSKTLAKLIPLIED-VLAAGEIQPPAPPEDAQPVA 290
           D   R   RD       L + +  I+  +L  G +      EDA   A
Sbjct: 250 DGVTRRLLRDRINEEGLLERCVRDIKALLLGEGSVGAQGEAEDAGESA 297


>UniRef50_Q0AA34 CRISPR-associated protein Cas1 n=11 Tax=Bacteria RepID=Q0AA34_ALHEH
          Length = 298

 Score =  146 bits (368), Expect = 9e-34,   Method: Compositional matrix adjust.
 Identities = 91/277 (32%), Positives = 143/277 (51%), Gaps = 10/277 (3%)

Query: 9   IPLKDRVSMIFLQYGQIDVIDGAFVLI-----DKTGIRTHIPVGSVACIMLEPGTRVSHA 63
           IP  DR  +++L  G++ V DG          D       IP   ++ I+L PG+ V+H 
Sbjct: 18  IPHVDRHGLLWLTRGRLYVEDGTLHFTAAESEDLAAGDYAIPYQGLSMILLGPGSTVTHD 77

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
            +RL A+ GTLL  +G  G + Y +   G  RSD     A L  ++  RL V R+M+  R
Sbjct: 78  VLRLLARHGTLLAAIGGGGTKYYTAPPMGQGRSDVARRHATLWANKTQRLDVARRMYAFR 137

Query: 124 FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
           FG   P  + +  LRGIEG R++  Y + A ++G+ W GRRY+  +    D  NQ I+ A
Sbjct: 138 FGRVLP-HKDIAVLRGIEGGRIKELYRVEASRFGIPWKGRRYNRNNPSAADVPNQAINHA 196

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            + +    + A+ A G  P +GF+H     +F  DIAD+ + +  VP AF+ AR+   +P
Sbjct: 197 ATFVEAAADIAVAATGALPPLGFIHEESSNAFTLDIADLYRGEITVPLAFQAARKVLDDP 256

Query: 244 ----DREVRLACRDIFRSSKTLAKLIPLIEDVLAAGE 276
               +R +R      F+  K + K+I  I+D++ A +
Sbjct: 257 TLSIERTLRRDAASAFQRHKVIPKMIDRIKDLINADD 293


>UniRef50_Q47PJ6 CRISPR-associated protein, Cas1 family n=4 Tax=Actinomycetales
           RepID=Q47PJ6_THEFY
          Length = 332

 Score =  143 bits (361), Expect = 6e-33,   Method: Compositional matrix adjust.
 Identities = 86/241 (35%), Positives = 136/241 (56%), Gaps = 8/241 (3%)

Query: 11  LKDRVSMIFLQYGQIDVID-GAFVLIDKTGIRTH---IPVGSVACIMLEPGTRVSHAAVR 66
           + D +S +++   +I   D G    ++    R H   IP  S+AC++L PGT ++  A+ 
Sbjct: 19  VSDGLSFLYVDVCRIVQTDTGVCAEVETETGRIHRVPIPTASLACVLLGPGTSITSPAMA 78

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLL-YQAKLALDEDLRLKVVRKMFELRFG 125
              +  T +V  G  G+  Y S  P   R+ K +  QA+   D+  R  V  +M+E+RFG
Sbjct: 79  TFMRHNTTVVTCGAGGILNYGSF-PAPNRTTKWIDRQARAYSDDRRRRDVAVRMYEMRFG 137

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
           E  P   S+E+LR +EG+R++A Y  LA +  V    R Y+P DW+  D +N+ +SA+ +
Sbjct: 138 EEPPPGASIERLRQLEGARMKALYRSLAAKNRVKPFKRNYNPHDWDDQDPVNKALSASNA 197

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDR 245
            LYGV  + +   G  PA+GF+H+GK  +FVYDIAD+ K  T +P AF ++R     P++
Sbjct: 198 ALYGVVHSVLAHLGCHPALGFIHSGKQDAFVYDIADLYKARTTIPLAFSLSRT--ANPEQ 255

Query: 246 E 246
           E
Sbjct: 256 E 256


>UniRef50_A3LCN8 Putative uncharacterized protein n=1 Tax=Pseudomonas aeruginosa
          2192 RepID=A3LCN8_PSEAE
          Length = 112

 Score =  138 bits (348), Expect = 2e-31,   Method: Compositional matrix adjust.
 Identities = 64/78 (82%), Positives = 73/78 (93%)

Query: 5  PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
          PL P+P+KDR+SM+F+QYGQIDV DGAFV+ID+TG+R HIPVGSVACIMLEPGTRVSHAA
Sbjct: 4  PLKPLPMKDRLSMVFVQYGQIDVRDGAFVVIDQTGVRMHIPVGSVACIMLEPGTRVSHAA 63

Query: 65 VRLAAQVGTLLVWVGEAG 82
          V LA+ VGTLLVWVGEAG
Sbjct: 64 VHLASTVGTLLVWVGEAG 81


>UniRef50_B6IWM1 CRISPR-associated protein Cas1, putative n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM1_RHOCS
          Length = 281

 Score =  138 bits (347), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 85/270 (31%), Positives = 138/270 (51%), Gaps = 6/270 (2%)

Query: 9   IPLKDRVSMIFLQYGQIDVIDGAFVL-IDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRL 67
           IP K R  +I+++  ++ + +G+ V+  D  G    +P   +  ++L PG+ ++H AVR 
Sbjct: 13  IPQKSRNGLIYVERCRLSIDNGSLVIAFDDRGEELELPYQRLNAVLLGPGSSITHDAVRH 72

Query: 68  AAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP 127
            +  GT L +VG  G R+Y +       S     QA     E  R+ V ++M+  RFGE 
Sbjct: 73  CSGHGTCLAFVGSDGTRLYTAPPLFDRDSTLARQQATWWAGESTRIMVAKRMYAKRFGE- 131

Query: 128 APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCL 187
            P   S++ LRG+E +R+R +Y L+A Q G+ W GRR+D  D +  D  NQ I+   + +
Sbjct: 132 TPRATSLDSLRGMEAARIRHSYELIAAQAGIVWRGRRFDRSDPDGDDLPNQAINHVVTAV 191

Query: 188 YGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR-NPGEPDRE 246
                 A+ A G  P +GF+H     S+  DI D+ +    VP AF   +R + G  D  
Sbjct: 192 EACVAIAVQATGTLPPLGFLHEDSAKSWTLDICDLYRTSVTVPLAFRCVKRIDQGATDSL 251

Query: 247 VRLACRDI---FRSSKTLAKLIPLIEDVLA 273
            R+  R +    R +  +  +I  I++VLA
Sbjct: 252 DRICRRAVSAHVRDTGFIDTIIDDIKEVLA 281


>UniRef50_C2KP50 CRISPR-associated Cas1 family protein n=5 Tax=Actinomycetales
           RepID=C2KP50_9ACTO
          Length = 312

 Score =  109 bits (273), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 74/274 (27%), Positives = 133/274 (48%), Gaps = 17/274 (6%)

Query: 9   IPLKDRVSMIFLQYGQI--------DVIDGAFVLIDKTGIR--THIPVGSVACIMLEPGT 58
           I L+DRVS ++L+Y Q+         + +G     D+  ++    IPV  +A + L PGT
Sbjct: 19  IRLEDRVSYLYLEYCQVIQNHTGVAAISEGNHDSEDREPLKRIIQIPVAGLAVLFLGPGT 78

Query: 59  RVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRK 118
            ++  A+   ++ G  +++ G  G   Y+      + S   + QA L  DE    K  + 
Sbjct: 79  SITQPAMASCSRAGLTVIFSGGGGCPYYSHAMALTSSSRWAIAQAHLVADERNARKAAKF 138

Query: 119 MFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQ 178
           +++ + G       ++ Q+RG+EGS ++  Y  L++++ V  NG R   +D    D +NQ
Sbjct: 139 LYKRQLGIDIERELTISQMRGLEGSLIKKRYRELSREFKV--NGFR---RDTGGEDVLNQ 193

Query: 179 CISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR 238
            ++     LYG   +A  A G  PA+G +H G   S ++D+AD+ K +  +P +F    +
Sbjct: 194 ALNLVNGILYGCAASACAALGVNPALGIIHRGDIRSLLFDVADLYKPNAALPISFRSVSK 253

Query: 239 NPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
           +  EP +  R   R        L  +I ++ +VL
Sbjct: 254 D--EPLKFARKEMRRFIYEQNVLENMISILMNVL 285


>UniRef50_Q3J7J6 CRISPR-associated protein, Cas1 family n=2 Tax=Nitrosococcus oceani
           RepID=Q3J7J6_NITOC
          Length = 295

 Score = 75.1 bits (183), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 78/295 (26%), Positives = 123/295 (41%), Gaps = 35/295 (11%)

Query: 8   PIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTH---IPVGSVACIMLEPGTRVSHAA 64
           PI    R  + +L++ ++   D   V   + G  T    IP  +   I+L  GT ++ AA
Sbjct: 2   PILPSHRQGLYYLEHCRVMAKDERVVYACQEGAFTKFFAIPPANTNVILLGSGTSLTQAA 61

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR- 123
            RL A    ++ +VG  G  ++ + Q     ++      +L  D D RLKV +     R 
Sbjct: 62  ARLLASEQVMVAFVGGGGSPLFLASQNEYRPTEYCQAWMRLWQDNDQRLKVAKTFQRNRA 121

Query: 124 ---------FGEPAPARRSVE----------QLRGIEGSRVRATYALLAKQYGVTW---- 160
                      EP P + S+E          +L G  G+ + A  A  AK+    W    
Sbjct: 122 EFLMQQWPKLAEPKPHKASLEKLAERYLADIELAGDNGT-ILAQEAKFAKKLYKFWANCT 180

Query: 161 ---NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH-TGKPLSFV 216
              N  R DP   +  D  N  +      +YG+  A +   G   ++  +H T +  + V
Sbjct: 181 ETENFTR-DPGKRDFNDPFNSYLDHGNYLVYGIAAAVLWVLGIPHSLPVIHGTTRRGALV 239

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDV 271
           +D+ADIIK   V+P AF+ A    G  D+E+R AC      S  +  L   I+ V
Sbjct: 240 FDVADIIKDTCVMPIAFQHAA--AGRSDQEMRQACIAWLDESHAMTFLFQSIKRV 292


>UniRef50_C6CA70 CRISPR-associated protein Cas1 n=56 Tax=Bacteria RepID=C6CA70_DICDC
          Length = 333

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 76/311 (24%), Positives = 132/311 (42%), Gaps = 48/311 (15%)

Query: 6   LNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRT---HIPVGSVACIMLEPGTRVSH 62
           L  I    R ++ +LQ+ +I V  G    + + G ++   +IP+ + + +ML  GT V+ 
Sbjct: 10  LKTILHSKRANIYYLQHCRILVNGGRVEYVTEEGNQSLYWNIPIANTSVVMLGTGTSVTQ 69

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARS-----------DKLLYQAKLALDEDL 111
           AA+R  A+ G ++ + G  G  ++A+ +   A S           + L        +E  
Sbjct: 70  AAMREFARAGVMVGFCGSGGTPLFAANEAEVAVSWLSPQSEYRPTEYLQDWVSFWFNEQQ 129

Query: 112 RLKVVRKMFELRFGEPAP-------ARRS--------VEQL-----RGIEGSR----VRA 147
           RL       ++R G+          AR S        VE L     +G+   R    V  
Sbjct: 130 RLAAAIAFQQVRIGQIRQHWLGGRLARESRFTIKPEHVEALLNRYQQGLVDCRTSNDVLV 189

Query: 148 TYALLAKQ-YGVTWNGRRY-DPKDWEKG---DTINQCISAATSCLYGVTEAAILAAGYAP 202
             A++ K  Y +  N   Y D    ++G   D  N+ +       YG+   A+   G   
Sbjct: 190 QEAMMTKALYRLAANAVSYGDFTRAKRGGGTDLANRFLDHGNYLAYGLAAVALWVLGLPH 249

Query: 203 AIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKT 260
            +  +H GK      V+D+AD+IK   ++P+AF  A    GE +++ R  C   FR ++ 
Sbjct: 250 GLAVLH-GKTRRGGLVFDVADLIKDALILPQAFIAAM--EGEDEQDFRQRCLTAFRQAEA 306

Query: 261 LAKLIPLIEDV 271
           L  +I  ++ V
Sbjct: 307 LDVMIDSLQQV 317


>UniRef50_D1BQ37 CRISPR-associated protein Cas1 n=1 Tax=Veillonella parvula DSM 2008
           RepID=D1BQ37_VEIPT
          Length = 331

 Score = 56.6 bits (135), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 44/147 (29%), Positives = 68/147 (46%), Gaps = 9/147 (6%)

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYGVTW--NGRRYDPKDWEKGDTINQCISAATSCLYG 189
           + VE LRGIEG   R  +++L       W  +GR+  P      D +N  +S   S L  
Sbjct: 149 KKVETLRGIEGLASRTYFSVLGHVLSEPWEFSGRKRHP----SPDPVNAILSYGYSFLER 204

Query: 190 VTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREV 247
              A +L AG    IG +H+   +  S VYD+ DI + D +     ++  R+   P+ + 
Sbjct: 205 EVRACLLTAGLDVRIGVLHSTNNRKDSLVYDVMDIFRQDIIDRFVLKLLNRHMILPE-DF 263

Query: 248 RLACRDIFRSSKTLAKLIPLIEDVLAA 274
            L+ R  F S +   K + L ED + A
Sbjct: 264 DLSERGCFLSKEANKKWVELYEDYMKA 290


>UniRef50_C8Q0H7 CRISPR-associated protein Cas1 n=6 Tax=Proteobacteria
           RepID=C8Q0H7_9GAMM
          Length = 334

 Score = 47.8 bits (112), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 60/304 (19%), Positives = 119/304 (39%), Gaps = 48/304 (15%)

Query: 8   PIPLKDRVSMIFLQYGQIDVIDGAFVLIDKT----GIRTHIPVGSVACIMLEPGTRVSHA 63
           P+ L  R  + +L+  ++ + D   V + ++        +IP  + A ++L  G+ ++ A
Sbjct: 28  PLMLSKRACVFYLERVRVILKDDRIVYLTESMQPIEHFYNIPEKNTAFLLLGKGSSITDA 87

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYAS--------------------GQPGGARSDKLLYQA 103
           A R  A+   ++ + G  G  ++++                               L  A
Sbjct: 88  AARRLAESNVMVGFCGSGGSPLFSALDLTFLAPQSEYRPTEYMQIWMKAWLDDTTRLLMA 147

Query: 104 KLALDEDLRLKVVRKMFE-----------------LRFGEPAPARRSVEQLRGIEGSRVR 146
           K+ L E  R+++V+K ++                 + F +   +  + EQL   EG   +
Sbjct: 148 KVLLQE--RIEIVKKYWQKNPLLTSYGIRLDESAVVNFSQAIESAMNQEQLLTAEGRWAK 205

Query: 147 ATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGF 206
             Y  LA+  G  +        + +  D  N  +       YG    A+   G + A+  
Sbjct: 206 VLYKSLAEGCGFKFTREEGKNANDDIADIANSYLDHGNYIAYGYAAVALHGLGISFALPM 265

Query: 207 VHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKL 264
           +H GK      V+D+AD++K   V+P+AF  A+   G   +E R+   +I +    L  +
Sbjct: 266 LH-GKTRRGGLVFDVADLVKDAMVMPQAFISAK--LGHNQKEFRMQLIEICQDQDVLDYM 322

Query: 265 IPLI 268
              +
Sbjct: 323 FGFV 326


>UniRef50_D2QT50 CRISPR-associated protein Cas1 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QT50_9SPHI
          Length = 351

 Score = 46.6 bits (109), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 18/130 (13%)

Query: 125 GEPAPARRSV----EQLRGIEGSRVRATYALLA----KQYGVTWNGRRYDPKDWEKGDTI 176
           GE  PA   V    + LRG+EG+  R  +  L+    K+Y   ++GR   P      D  
Sbjct: 157 GEQTPATTCVADVADTLRGLEGTAGRLYFETLSYVLPKEY--QFSGRSSRPAQ----DAF 210

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK--FDTVVPKA 232
           N  ++     LYG  E  ++ AG  P +GF+H      LS VYD  +  +   D VV + 
Sbjct: 211 NAFLNYGYGMLYGKVEKTLMMAGLDPYVGFLHRDDYNQLSMVYDFIEPYRGWTDEVVFRL 270

Query: 233 FEIARRNPGE 242
           F   + N   
Sbjct: 271 FTAKKVNKAH 280


>UniRef50_C8W2P4 CRISPR-associated protein Cas1 n=1 Tax=Desulfotomaculum acetoxidans
           DSM 771 RepID=C8W2P4_DESAS
          Length = 545

 Score = 45.4 bits (106), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 60/262 (22%), Positives = 106/262 (40%), Gaps = 60/262 (22%)

Query: 20  LQYGQIDVIDGAFVLIDKTGIRTH----------IPVGSVACIMLEPGTRVSHAAVRLAA 69
           L  G++  +D     + K G R            IP+ ++  ++L     +S   ++L  
Sbjct: 210 LNLGRVLYVDEPGAYVRKKGERVQVTRDKEVLVDIPLCNLEQLVLAGTVNISAQVIKLLL 269

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKL-LYQAKLALDEDLRLKVV----------RK 118
             GT + +V  AG + Y S QP   ++  L + Q K   D +LRLK             +
Sbjct: 270 DRGTEVHFVSRAG-KYYGSLQPALTKNSALRIAQHKAYQDMELRLKYAVLFVQGKLANMR 328

Query: 119 MFELRFGEPAPARR-------------------SVEQLRGIEGSRVRATYALLAKQYGVT 159
              LR+      ++                   S+  L GIEG+  R  + +        
Sbjct: 329 TILLRYNRDLKEKQLEEAICRLKSLSKNLYKADSLNSLMGIEGAATREYFRVF------N 382

Query: 160 WNGRRYDPKDWEK------GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH---TG 210
           +  +++ P ++++      GD +N  +S A + L     A++   GY P IGF+H    G
Sbjct: 383 YMIKQHVPFNFQQRSRRPPGDPVNALLSFAYTLLTKDMIASVSIVGYDPYIGFLHRSDYG 442

Query: 211 KP---LSFVYDIADIIKFDTVV 229
           +P   L F+ +   I+  D+VV
Sbjct: 443 RPALALDFIEEFRPIVA-DSVV 463


>UniRef50_C1XN81 CRISPR-associated protein Cas1 n=2 Tax=Meiothermus
           RepID=C1XN81_MEIRU
          Length = 323

 Score = 45.4 bits (106), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 14/116 (12%)

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALLA---KQYGVTWNGRRYDPKDWEKGDTINQCISA 182
           E  P  RS+E LRGIEG+  RA +A L      YG  ++GR   P      D +N  +S 
Sbjct: 136 EALPQARSLEALRGIEGNAARAYFAGLQAVLAPYG--FSGRNRRPPT----DAVNAALSY 189

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHT-GKPL-SFVYDIADIIK---FDTVVPKAF 233
               L G    A+  AG  P +G +HT G+ + +  +D+ +  +    D VV  AF
Sbjct: 190 GYMVLLGRVLLALGIAGLHPELGLLHTEGRRVPALAFDLMEEFRVSVVDAVVIAAF 245


>UniRef50_B8CYA1 CRISPR-associated protein Cas1 n=2 Tax=cellular organisms
           RepID=B8CYA1_HALOH
          Length = 325

 Score = 44.3 bits (103), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 19/132 (14%)

Query: 114 KVVRKMFELRFGEPAPARRSVEQLR----GIEGSRVRATYA----LLAKQYGVTWNGRRY 165
           K ++++ ELR  +       +E +R    G EG+  R  +A    LL  +Y   +NGR +
Sbjct: 134 KKIKEICELR-NKLEKVTGYIEDVRNTIMGYEGNISRKYFASLSFLLPDRY--KFNGRSF 190

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADII 223
            P +    D  N  ++     LYG  E A++ AG  P +G +HT      SFV+D  +  
Sbjct: 191 RPAE----DEFNCLLNYGYGVLYGKVEKALIIAGLDPYVGILHTDGYNKKSFVFDFIEPY 246

Query: 224 K--FDTVVPKAF 233
           +   D VV K F
Sbjct: 247 RHHIDRVVMKLF 258


>UniRef50_C0QHV1 Putative CRISPR-associated protein (Uncharacterized protein,
           predicted to be involved in DNA repair) n=1
           Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QHV1_DESAH
          Length = 338

 Score = 43.5 bits (101), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 10/119 (8%)

Query: 107 LDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRR 164
           +D  L ++ + +  E+  GE     R+   + G+EG+  RA + +LA+       + GR 
Sbjct: 132 IDTILAIEKILQTLEVTDGENVIDLRNT--IMGLEGTSARAYFKVLARAMPEKYRFKGRS 189

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIAD 221
             P      D  N  ++     LYG  E A + AG  P IGF+HT      S V+D+ +
Sbjct: 190 RRPA----KDPFNAVLNYCYGMLYGKVEKACIIAGLDPFIGFLHTDNYNKKSLVFDLIE 244


>UniRef50_Q96X75 Putative uncharacterized protein ST2634 n=1 Tax=Sulfolobus tokodaii
           RepID=Q96X75_SULTO
          Length = 317

 Score = 43.5 bits (101), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 50/212 (23%), Positives = 88/212 (41%), Gaps = 27/212 (12%)

Query: 31  AFVLIDKTGIRTHIPVGSV-ACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV---RVY 86
            FV+  K G + ++    V   +++  G  V+  A+RLA   G  ++++   G    R++
Sbjct: 32  TFVISKKDGKKVNVSPAEVDQIVIMTSGVTVTSKAIRLALDHGIDIIFLDSRGNPFGRLF 91

Query: 87  ASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVR 146
            S       + K  Y A L  +E+    + R++ + +    A   +   +  GIEG+   
Sbjct: 92  HSEPIKTVETRKAQYLAILKGEEE----IPREIIKSKIKNQANHIKFWFKKLGIEGN--- 144

Query: 147 ATYALLAKQYGVTWNGRRY-----------DPKDWEKGDTINQCISAATSCLYGVTEAAI 195
             Y L+  +        RY             +D E  D  N   + A + LY   +  +
Sbjct: 145 -DYKLIEGKDDDEATAARYYWHALGRIIPMKGRDPESTDPFNVSFNYAYAILYSNIQRVL 203

Query: 196 LAAGYAPAIGFVH---TGKPLSFVYDIADIIK 224
              G  P  GF+H   +GKP S VYD +++ K
Sbjct: 204 QLVGLDPYAGFIHKDRSGKP-SLVYDFSEMFK 234


>UniRef50_B8D4S7 CRISPR-associated protein Cas1 n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D4S7_DESK1
          Length = 328

 Score = 43.1 bits (100), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 21/115 (18%)

Query: 118 KMFELRFGEPAPARRSVEQLRGIEGSRVRATY----ALLAKQYGVTWNGRRYDPKDWEKG 173
           +M E  F E   AR   E+LR +E    R  +     L+ K+ G       ++ +D +  
Sbjct: 146 RMLEAEFEE---AR---EKLRQLEAEAARIYWPSLSILIPKELG-------FNSRDQDSE 192

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKF 225
           D +N  ++ A   LYG +   ++ AG  P  GF+HT   GKP+   +D+ ++ +F
Sbjct: 193 DLVNTSLNYAYGILYGESWKVLVLAGLDPYAGFMHTDRSGKPV-LAFDLIEMFRF 246


>UniRef50_A1ZHZ5 Crispr-associated protein Cas1 n=1 Tax=Microscilla marina ATCC
           23134 RepID=A1ZHZ5_9SPHI
          Length = 344

 Score = 43.1 bits (100), Expect = 0.014,   Method: Compositional matrix adjust.
 Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 14/118 (11%)

Query: 135 EQLRGIEGSRVRATYA----LLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
           + LRG+EG+  R  +     +LAK+Y   + GR   P      D  N  ++     LY +
Sbjct: 168 DTLRGLEGTAGRLYFETLSYVLAKEY--QFAGRSKRPAH----DAFNAFLNYGYGILYSM 221

Query: 191 TEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK--FDTVVPKAFEIARRNPGEPD 244
            E A++ AG  P +GF+H       S VYD  +  +   + VV K F   + N    D
Sbjct: 222 VEHALVIAGIDPFVGFMHRDGYNQRSMVYDFIEPYRGHVEQVVVKLFTAKKVNQSHTD 279


>UniRef50_A3XI90 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XI90_9FLAO
          Length = 332

 Score = 41.6 bits (96), Expect = 0.032,   Method: Compositional matrix adjust.
 Identities = 34/113 (30%), Positives = 48/113 (42%), Gaps = 10/113 (8%)

Query: 135 EQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTE 192
           E  RG EGS  R  +  LA       ++ GR + P      D  N  ++ A   LY   E
Sbjct: 164 ESFRGWEGSAGRHYFEALATCIPDAYSFKGRSFRPAQ----DEFNALLNYAYGILYSRVE 219

Query: 193 AAILAAGYAPAIGFVHTG--KPLSFVYDIAD--IIKFDTVVPKAFEIARRNPG 241
            A++ AG  P +GF+H       S VYD  +   I  +  V K+F   + N  
Sbjct: 220 RALMLAGLDPFVGFMHRDDYNSKSLVYDFIEPYRIYAERFVFKSFSSKKMNKS 272


>UniRef50_Q2FL78 CRISPR-associated protein, Cas1 family n=1 Tax=Methanospirillum
           hungatei JF-1 RepID=Q2FL78_METHJ
          Length = 331

 Score = 41.6 bits (96), Expect = 0.036,   Method: Compositional matrix adjust.
 Identities = 51/216 (23%), Positives = 87/216 (40%), Gaps = 38/216 (17%)

Query: 41  RTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLL 100
           RT  P+G +  + +     +S AAVRL    G  +  +   G   +    P G  +    
Sbjct: 35  RTLSPLG-LDLLAIAGDHSISTAAVRLVTSHGGAIALMDGLG-NPFGHFLPLGRSALIEQ 92

Query: 101 YQAKLALDEDLRLKVVRKMF------------------------ELRFGEPAPAR----R 132
           Y+A+ +  E+ RL++ R +                         E+R  E A  +    +
Sbjct: 93  YEAQASAPEERRLEIARSICTGALENKRTLLSNLERIRGFDLSREIRLVEDAQDKALECQ 152

Query: 133 SVEQLRGIEGSRVRATYALLAKQYGVTWN--GRRYDPKDWEKGDTINQCISAATSCLYGV 190
           S++ LRG+EGS   A +   +  +   W   GR  +P      D +N  +S     LY  
Sbjct: 153 SLDSLRGVEGSGAHAYFQGFSLAFDEEWGFLGRSQNPAT----DPVNSLLSYGYGMLYIQ 208

Query: 191 TEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIK 224
              A++ +GY+P  G  H    K  + VYD+ +  +
Sbjct: 209 ARQALVLSGYSPYYGAYHETYKKQEALVYDLVEEFR 244


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q46896 Uncharacterized protein ygbT n=119 Tax=cellular ...   428   e-118
UniRef50_D1A5U2 CRISPR-associated protein Cas1 n=3 Tax=Actinomyc...   391   e-107
UniRef50_D1NTI3 CRISPR-associated protein Cas1 n=10 Tax=Bacteria...   384   e-105
UniRef50_Q2JWC7 CRISPR-associated protein Cas1 n=3 Tax=Chroococc...   383   e-105
UniRef50_C7QEM2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria ...   380   e-104
UniRef50_D1CAI8 CRISPR-associated protein Cas1 n=3 Tax=Bacteria ...   373   e-102
UniRef50_D1CGD6 CRISPR-associated protein Cas1 n=7 Tax=cellular ...   371   e-101
UniRef50_D2RB04 CRISPR-associated endonuclease Cas1, ECOLI subty...   370   e-101
UniRef50_B4V4P5 Crispr-associated protein cas1 n=4 Tax=Streptomy...   368   e-101
UniRef50_C1YVP5 CRISPR-associated protein Cas1 n=1 Tax=Nocardiop...   367   e-100
UniRef50_Q3ZZ81 CRISPR-associated protein Cas1 n=4 Tax=Bacteria ...   365   1e-99
UniRef50_A8M406 CRISPR-associated protein Cas1 n=5 Tax=Actinomyc...   359   6e-98
UniRef50_C7LYW4 CRISPR-associated protein Cas1 n=1 Tax=Acidimicr...   357   3e-97
UniRef50_B1VIX8 CRISPR-associated protein n=6 Tax=Corynebacteriu...   355   1e-96
UniRef50_C7MTM5 CRISPR-associated protein, Cas1 family n=6 Tax=A...   342   9e-93
UniRef50_Q03C58 CRISPR-associated protein n=3 Tax=Lactobacillus ...   341   2e-92
UniRef50_C2BS02 CRISPR-associated protein n=1 Tax=Mobiluncus cur...   339   8e-92
UniRef50_C7MTL6 CRISPR-associated protein, Cas1 family n=4 Tax=A...   338   1e-91
UniRef50_C4X9I5 CRISPR-associated Cas1 family protein n=12 Tax=B...   313   5e-84
UniRef50_B6IWM1 CRISPR-associated protein Cas1, putative n=1 Tax...   299   7e-80
UniRef50_C9M9R9 CRISPR-associated protein Cas1 n=1 Tax=Jonquetel...   299   8e-80
UniRef50_Q47PJ6 CRISPR-associated protein, Cas1 family n=4 Tax=A...   296   9e-79
UniRef50_Q21QB1 CRISPR-associated protein Cas1 n=1 Tax=Rhodofera...   294   3e-78
UniRef50_Q0AA34 CRISPR-associated protein Cas1 n=11 Tax=Bacteria...   291   3e-77
UniRef50_C2KP50 CRISPR-associated Cas1 family protein n=5 Tax=Ac...   278   2e-73
UniRef50_Q3J7J6 CRISPR-associated protein, Cas1 family n=2 Tax=N...   257   3e-67
UniRef50_C8Q0H7 CRISPR-associated protein Cas1 n=6 Tax=Proteobac...   236   9e-61
UniRef50_C6CA70 CRISPR-associated protein Cas1 n=56 Tax=Bacteria...   231   3e-59
UniRef50_D1BQ37 CRISPR-associated protein Cas1 n=1 Tax=Veillonel...   145   1e-33
UniRef50_D2QT50 CRISPR-associated protein Cas1 n=1 Tax=Spirosoma...   116   9e-25
UniRef50_A3LCN8 Putative uncharacterized protein n=1 Tax=Pseudom...   110   6e-23

Sequences not found previously or not previously below threshold:

UniRef50_B7GYY4 CRISPR-associated protein Cas1 n=8 Tax=Proteobac...   213   5e-54
UniRef50_A9BUF1 CRISPR-associated protein Cas1 n=33 Tax=Proteoba...   199   1e-49
UniRef50_C8W2P4 CRISPR-associated protein Cas1 n=1 Tax=Desulfoto...    99   3e-19
UniRef50_B9LWK7 CRISPR-associated protein Cas1 n=4 Tax=Halobacte...    95   2e-18
UniRef50_A4X3M4 CRISPR-associated protein, Cas1 family n=4 Tax=A...    94   7e-18
UniRef50_O57912 Putative uncharacterized protein PH0173 n=1 Tax=...    92   3e-17
UniRef50_A1ZHZ5 Crispr-associated protein Cas1 n=1 Tax=Microscil...    90   1e-16
UniRef50_A9AYP8 CRISPR-associated protein Cas1 n=1 Tax=Herpetosi...    90   1e-16
UniRef50_B8CYA1 CRISPR-associated protein Cas1 n=2 Tax=cellular ...    89   2e-16
UniRef50_Q2FL78 CRISPR-associated protein, Cas1 family n=1 Tax=M...    89   2e-16
UniRef50_D2NTT1 Uncharacterized protein predicted to be involved...    88   3e-16
UniRef50_B0VIK5 Putative uncharacterized protein n=1 Tax=Candida...    87   6e-16
UniRef50_Q1CWU5 CRISPR-associated protein Cas1 n=1 Tax=Myxococcu...    86   1e-15
UniRef50_Q96X75 Putative uncharacterized protein ST2634 n=1 Tax=...    86   1e-15
UniRef50_A3XI90 Putative uncharacterized protein n=1 Tax=Leeuwen...    86   2e-15
UniRef50_C7QUZ4 CRISPR-associated protein Cas1 n=8 Tax=Cyanobact...    85   2e-15
UniRef50_C1ZJF3 CRISPR-associated protein, Cas1 family; CRISPR-a...    85   3e-15
UniRef50_C7NA04 CRISPR-associated protein Cas1 n=1 Tax=Leptotric...    84   6e-15
UniRef50_UPI0001C16754 protein of unknown function DUF48 n=1 Tax...    84   8e-15
UniRef50_C0QHV1 Putative CRISPR-associated protein (Uncharacteri...    84   8e-15
UniRef50_B7KMR5 CRISPR-associated protein Cas1 n=3 Tax=Chroococc...    82   2e-14
UniRef50_D0MKV7 CRISPR-associated protein Cas1 n=1 Tax=Rhodother...    82   2e-14
UniRef50_A2BKJ8 Universally conserved protein n=1 Tax=Hypertherm...    80   7e-14
UniRef50_A6UVX9 CRISPR-associated protein Cas1 n=2 Tax=Methanoco...    80   1e-13
UniRef50_C1XN81 CRISPR-associated protein Cas1 n=2 Tax=Meiotherm...    79   2e-13
UniRef50_A8UXX8 Putative uncharacterized protein n=1 Tax=Hydroge...    79   2e-13
UniRef50_UPI00016C522C CRISPR-associated protein Cas1/Cas4 n=1 T...    78   4e-13
UniRef50_B9K7F7 CRISPR-associated protein, Cas1 family n=1 Tax=T...    78   4e-13
UniRef50_A9GDF7 Putative uncharacterized protein n=1 Tax=Sorangi...    77   8e-13
UniRef50_C1XWQ6 CRISPR-associated protein, Cas1 family n=3 Tax=T...    77   8e-13
UniRef50_A1A2M8 CRISPR-associated DNA polymerase n=14 Tax=Bacter...    77   9e-13
UniRef50_D0YU98 Crispr-associated protein Cas1 n=1 Tax=Mobiluncu...    77   1e-12
UniRef50_C3MX12 CRISPR-associated protein Cas1 n=11 Tax=Sulfolob...    76   1e-12
UniRef50_C4G3M4 Putative uncharacterized protein n=1 Tax=Abiotro...    76   1e-12
UniRef50_C9M4E6 CRISPR-associated protein cas1 n=1 Tax=Lactobaci...    75   2e-12
UniRef50_A6UNF5 CRISPR-associated protein Cas1 n=1 Tax=Methanoco...    75   2e-12
UniRef50_A5UXM3 CRISPR-associated protein, Cas1 family n=4 Tax=C...    75   2e-12
UniRef50_B7IHY4 Cas crispr-associated protein Cas1 n=4 Tax=Bacte...    75   3e-12
UniRef50_B7C8S2 Putative uncharacterized protein n=2 Tax=Eubacte...    75   3e-12
UniRef50_A8ABK8 CRISPR-associated protein Cas1 n=1 Tax=Ignicoccu...    75   3e-12
UniRef50_A1BI39 CRISPR-associated protein Cas1 n=5 Tax=Chlorobia...    75   3e-12
UniRef50_Q53W21 Putative uncharacterized protein TTHB145 n=3 Tax...    74   6e-12
UniRef50_C2GEC7 Crispr-associated protein Cas1 n=2 Tax=Corynebac...    74   8e-12
UniRef50_Q65S18 Putative uncharacterized protein n=1 Tax=Mannhei...    73   1e-11
UniRef50_A7GY67 Crispr-associated protein Cas1 n=6 Tax=Campyloba...    73   1e-11
UniRef50_B0TFX3 Crispr-associated protein cas1 n=4 Tax=Clostridi...    72   2e-11
UniRef50_A7HMV0 CRISPR-associated protein Cas1 n=3 Tax=Thermotog...    72   3e-11
UniRef50_C1DUM1 Crispr-associated protein Cas1 n=18 Tax=Bacteria...    72   3e-11
UniRef50_B8GDW2 CRISPR-associated protein Cas1 n=1 Tax=Methanosp...    72   3e-11
UniRef50_D2PIT7 CRISPR-associated protein Cas1 n=2 Tax=Sulfolobu...    72   3e-11
UniRef50_UPI0001C41A73 CRISPR-associated protein Cas1-2 n=1 Tax=...    71   4e-11
UniRef50_Q8F1F5 Putative uncharacterized protein n=2 Tax=Leptosp...    71   5e-11
UniRef50_A5D0Y0 Uncharacterized protein n=40 Tax=cellular organi...    71   5e-11
UniRef50_C9M4Y8 CRISPR-associated protein Cas1 n=1 Tax=Jonquetel...    71   5e-11
UniRef50_C5BP90 CRISPR-associated protein Cas1 n=3 Tax=Gammaprot...    71   5e-11
UniRef50_A4J500 CRISPR-associated protein Cas1 n=1 Tax=Desulfoto...    71   5e-11
UniRef50_Q6L317 DNA polymerase n=2 Tax=Thermoplasmatales RepID=Q...    71   6e-11
UniRef50_A4FXZ8 CRISPR-associated protein, Cas1 family n=9 Tax=c...    71   6e-11
UniRef50_A7NP58 CRISPR-associated protein Cas1 n=6 Tax=Chlorofle...    70   6e-11
UniRef50_D2LF35 CRISPR-associated protein Cas1 n=1 Tax=Rhodomicr...    70   7e-11
UniRef50_Q2SIC8 CRISPR-associated protein Cas1 n=6 Tax=Gammaprot...    70   7e-11
UniRef50_Q74H36 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Geob...    70   8e-11
UniRef50_Q9YCL8 Putative CRISPR-associated protein Cas1 n=1 Tax=...    70   1e-10
UniRef50_A5ILM3 CRISPR-associated protein, Cas1 family n=3 Tax=B...    70   1e-10
UniRef50_C9LM09 CRISPR-associated protein Cas1 n=1 Tax=Dialister...    70   1e-10
UniRef50_D1N0J7 CRISPR-associated protein Cas1 n=1 Tax=Victivall...    70   1e-10
UniRef50_A7HNI6 CRISPR-associated protein Cas1 n=1 Tax=Fervidoba...    70   1e-10
UniRef50_B8GSH8 CRISPR-associated protein Cas1 n=1 Tax=Thioalkal...    70   1e-10
UniRef50_UPI000197AF65 hypothetical protein BACCOPRO_02409 n=1 T...    70   1e-10
UniRef50_A3MVN2 CRISPR-associated protein, Cas1 family n=4 Tax=T...    69   2e-10
UniRef50_B0K547 CRISPR-associated protein Cas1 n=12 Tax=Bacteria...    69   2e-10
UniRef50_Q8YZS6 Alr0381 protein n=6 Tax=Cyanobacteria RepID=Q8YZ...    69   2e-10
UniRef50_B2SPB2 Crispr-associated protein Cas1 n=56 Tax=Bacteria...    68   3e-10
UniRef50_A1WUP2 CRISPR-associated protein Cas1 n=1 Tax=Halorhodo...    68   3e-10
UniRef50_Q2LQX3 Uncharacterized protein predicted to be involved...    68   4e-10
UniRef50_Q6L363 DNA polymerase n=1 Tax=Picrophilus torridus RepI...    68   4e-10
UniRef50_B6IX22 CRISPR-associated protein Cas1, putative n=2 Tax...    68   4e-10
UniRef50_D0KYZ2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria ...    68   5e-10
UniRef50_Q7MRD4 Putative uncharacterized protein n=1 Tax=Wolinel...    68   5e-10
UniRef50_C0BZ41 Putative uncharacterized protein n=3 Tax=Clostri...    67   6e-10
UniRef50_C0FSR1 Putative uncharacterized protein n=1 Tax=Rosebur...    67   6e-10
UniRef50_C9LGP6 CRISPR-associated protein Cas1 n=3 Tax=Prevotell...    67   7e-10
UniRef50_C7RP03 CRISPR-associated protein Cas1 n=1 Tax=Candidatu...    67   7e-10
UniRef50_Q467D6 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Meth...    67   8e-10
UniRef50_A3CTI4 CRISPR-associated protein Cas1 n=1 Tax=Methanocu...    67   8e-10
UniRef50_C3MWK6 CRISPR-associated protein Cas1 n=6 Tax=Sulfolobu...    67   8e-10
UniRef50_B4W4R1 CRISPR-associated protein Cas1 n=1 Tax=Microcole...    67   9e-10
UniRef50_C7G6C1 CRISPR-associated protein Cas1 n=3 Tax=Firmicute...    67   1e-09
UniRef50_B9M9X7 Putative uncharacterized protein n=1 Tax=Diaphor...    67   1e-09
UniRef50_A1HM55 CRISPR-associated protein Cas1 n=2 Tax=Thermosin...    66   1e-09
UniRef50_Q0AW57 CRISPR-associated protein, Cas1 family n=1 Tax=S...    66   1e-09
UniRef50_B9YDC3 Putative uncharacterized protein n=1 Tax=Holdema...    66   1e-09
UniRef50_C3WS02 CRISPR-associated protein n=2 Tax=Fusobacterium ...    66   2e-09
UniRef50_B7A8Y4 CRISPR-associated protein Cas1 n=1 Tax=Thermus a...    66   2e-09
UniRef50_Q2NH78 Putative uncharacterized protein n=1 Tax=Methano...    66   2e-09
UniRef50_Q2RY11 CRISPR-associated protein, Cas1 family / CRISPR-...    65   2e-09
UniRef50_A8ABE8 CRISPR-associated protein Cas1 n=1 Tax=Ignicoccu...    65   2e-09
UniRef50_C8WTR3 CRISPR-associated protein Cas1 n=2 Tax=Alicyclob...    65   3e-09
UniRef50_Q74N45 NEQ017 n=1 Tax=Nanoarchaeum equitans RepID=Q74N4...    65   3e-09
UniRef50_B3PMY9 Putative uncharacterized protein n=1 Tax=Mycopla...    65   4e-09
UniRef50_A0LWB2 CRISPR-associated protein Cas1 n=1 Tax=Acidother...    65   4e-09
UniRef50_Q0ADY5 CRISPR-associated protein, Cas1 family n=2 Tax=N...    65   4e-09
UniRef50_B8D4S7 CRISPR-associated protein Cas1 n=1 Tax=Desulfuro...    65   4e-09
UniRef50_C8PKY6 Putative CRISPR-associated protein Cas1 n=1 Tax=...    64   5e-09
UniRef50_A3ZPG0 Putative uncharacterized protein n=1 Tax=Blastop...    64   5e-09
UniRef50_D2R8Z2 CRISPR-associated protein Cas1 n=1 Tax=Pirellula...    64   6e-09
UniRef50_B5IAF4 CRISPR-associated protein Cas1 n=3 Tax=Euryarcha...    64   6e-09
UniRef50_C9RRG3 CRISPR-associated protein Cas1 n=1 Tax=Fibrobact...    64   6e-09
UniRef50_Q2J7N9 CRISPR-associated protein Cas1 n=1 Tax=Frankia s...    63   8e-09
UniRef50_Q1J1U7 CRISPR-associated protein Cas1 n=1 Tax=Deinococc...    63   8e-09
UniRef50_D0MKP4 CRISPR-associated protein Cas1 n=1 Tax=Rhodother...    63   9e-09
UniRef50_B2RM83 CRISPR-associated protein Cas1 n=3 Tax=Bacteroid...    63   1e-08
UniRef50_B1YCK7 CRISPR-associated protein Cas1 n=2 Tax=Thermopro...    63   1e-08
UniRef50_C0QR16 Crispr-associated protein Cas1 n=23 Tax=Bacteria...    63   1e-08
UniRef50_O28401 Putative uncharacterized protein n=1 Tax=Archaeo...    62   2e-08
UniRef50_B4ATI8 Crispr-associated protein Cas1 n=5 Tax=Proteobac...    62   2e-08
UniRef50_O66692 Putative uncharacterized protein n=2 Tax=Aquific...    62   2e-08
UniRef50_C4FMU2 Putative uncharacterized protein n=1 Tax=Veillon...    62   2e-08
UniRef50_Q1Q3I6 Putative uncharacterized protein n=1 Tax=Candida...    62   3e-08
UniRef50_A2SRR7 CRISPR-associated protein, Cas1 family n=24 Tax=...    62   3e-08
UniRef50_Q2FQQ2 CRISPR-associated protein Cas1 n=2 Tax=Methanomi...    62   3e-08
UniRef50_B8G918 CRISPR-associated protein Cas1 n=5 Tax=Chlorofle...    62   3e-08
UniRef50_C5SD37 CRISPR-associated protein Cas1 n=1 Tax=Allochrom...    62   3e-08
UniRef50_Q3B3C1 CRISPR-associated protein, Cas1 family n=20 Tax=...    61   5e-08
UniRef50_C0W0W5 CRISPR-associated Cas1 family protein n=1 Tax=Ac...    61   5e-08
UniRef50_B3E1C9 CRISPR-associated protein Cas1 n=1 Tax=Methylaci...    61   6e-08
UniRef50_D2QAN8 CRISPR-associated protein Cas1 n=2 Tax=Bifidobac...    61   6e-08
UniRef50_C6HZN2 CRISPR-associated protein Cas1 n=1 Tax=Leptospir...    60   8e-08
UniRef50_B8DWG2 CRISPR-associated protein Cas1 n=4 Tax=Bifidobac...    60   9e-08
UniRef50_B5IHG3 CRISPR-associated protein Cas1 n=3 Tax=Acidulipr...    60   9e-08
UniRef50_A5UJ50 Uncharacterized protein predicted to be involved...    60   9e-08
UniRef50_Q8YWX6 Alr1468 protein n=4 Tax=Cyanobacteria RepID=Q8YW...    60   1e-07
UniRef50_A6DE65 Putative uncharacterized protein n=1 Tax=Caminib...    60   1e-07
UniRef50_A0LHZ4 CRISPR-associated protein, Cas1 family n=2 Tax=D...    60   1e-07
UniRef50_C0WRP8 CRISPR-associated protein n=18 Tax=Lactobacillac...    60   1e-07
UniRef50_Q8TVS6 Uncharacterized conserved protein n=1 Tax=Methan...    60   1e-07
UniRef50_B0JKW9 CRISPR-associated protein Cas1 n=6 Tax=Cyanobact...    59   2e-07
UniRef50_C6I8L1 CRISPR-associated protein n=1 Tax=Bacteroides sp...    59   2e-07
UniRef50_B9LX94 CRISPR-associated protein Cas1 n=2 Tax=Halobacte...    59   2e-07
UniRef50_Q1WVJ8 CRISPR-associated protein n=1 Tax=Lactobacillus ...    59   2e-07
UniRef50_Q1CW50 CRISPR-associated fusion protein Cas4/Cas1 n=5 T...    58   3e-07
UniRef50_Q03KT5 CRISPR-associated protein, Cas1 family n=5 Tax=S...    58   4e-07
UniRef50_Q5X8T5 Putative uncharacterized protein n=1 Tax=Legione...    58   5e-07
UniRef50_A4FJX8 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Sacc...    57   7e-07
UniRef50_B3EG05 CRISPR-associated protein Cas1 n=11 Tax=Bacteria...    57   8e-07
UniRef50_B8GLF6 CRISPR-associated Cas1/Cas4 family protein n=1 T...    57   9e-07
UniRef50_Q8F874 Putative uncharacterized protein n=1 Tax=Leptosp...    57   1e-06
UniRef50_A1RZT8 CRISPR-associated protein Cas1 n=1 Tax=Thermofil...    57   1e-06
UniRef50_A7I668 CRISPR-associated protein Cas1 n=1 Tax=Candidatu...    57   1e-06
UniRef50_D0LSW9 CRISPR-associated protein Cas1 n=1 Tax=Haliangiu...    56   1e-06
UniRef50_D0W646 CRISPR-associated protein Cas1 n=1 Tax=Neisseria...    56   2e-06
UniRef50_B7KM77 CRISPR-associated protein Cas1 n=1 Tax=Cyanothec...    55   2e-06
UniRef50_B1GZM4 CRISPR-associated protein Cas1 n=1 Tax=unculture...    55   3e-06
UniRef50_UPI0000F51762 hypothetical protein Faci_00015 n=1 Tax=F...    55   3e-06
UniRef50_D0MJ58 CRISPR-associated protein Cas1 n=1 Tax=Rhodother...    55   4e-06
UniRef50_C3WD45 CRISPR-associated protein cas1 n=1 Tax=Fusobacte...    55   4e-06
UniRef50_A8REI1 Putative uncharacterized protein n=2 Tax=unclass...    55   4e-06
UniRef50_B3W9S5 CRISPR-associated protein n=4 Tax=Lactobacillus ...    55   4e-06
UniRef50_Q2FPW6 CRISPR-associated protein Cas1 n=1 Tax=Methanosp...    55   5e-06
UniRef50_A1WH94 CRISPR-associated protein, Cas1 family n=5 Tax=P...    54   5e-06
UniRef50_A3DLB7 CRISPR-associated protein, Cas1 family n=1 Tax=S...    54   6e-06
UniRef50_A7BYC5 Protein containing DUF48 n=1 Tax=Beggiatoa sp. P...    54   6e-06
UniRef50_B5YJS2 Crispr-associated protein Cas1 n=1 Tax=Thermodes...    54   7e-06
UniRef50_C0A724 CRISPR-associated Cas1/Cas4 family protein n=1 T...    54   8e-06
UniRef50_C6MJ62 CRISPR-associated protein Cas1 n=5 Tax=Nitrosomo...    53   1e-05
UniRef50_Q7MTH7 CRISPR-associated protein Cas1 n=3 Tax=Porphyrom...    53   1e-05
UniRef50_B5ZLL1 CRISPR-associated protein Cas1 n=2 Tax=Gluconace...    53   1e-05
UniRef50_A1BI46 CRISPR-associated protein Cas1 n=2 Tax=Chlorobia...    53   1e-05
UniRef50_UPI0001BCCAFD hypothetical protein SnoxA4_00467 n=1 Tax...    53   2e-05
UniRef50_C8W3G7 CRISPR-associated protein Cas1 n=24 Tax=Bacteria...    52   2e-05
UniRef50_C5EZ73 Crispr-protein cas1 n=1 Tax=Helicobacter pulloru...    52   2e-05
UniRef50_A7HP88 CRISPR-associated protein Cas1 n=1 Tax=Parvibacu...    52   2e-05
UniRef50_C7V674 Predicted protein n=2 Tax=Enterococcus faecalis ...    52   2e-05
UniRef50_Q13CC1 CRISPR-associated protein, Cas1 family n=2 Tax=R...    52   3e-05
UniRef50_Q6A5T6 Putative uncharacterized protein n=1 Tax=Propion...    52   4e-05
UniRef50_Q03LF6 CRISPR-associated protein, Cas1 family n=6 Tax=S...    51   4e-05
UniRef50_B1X158 DUF48-containing protein n=12 Tax=Cyanobacteria ...    51   5e-05
UniRef50_B2KB47 CRISPR-associated protein Cas1 n=2 Tax=Elusimicr...    50   8e-05
UniRef50_B1L400 CRISPR-associated protein Cas1 n=2 Tax=Archaea R...    50   1e-04
UniRef50_B9M5J4 CRISPR-associated protein Cas1 n=9 Tax=Bacteria ...    50   1e-04
UniRef50_B4AQ39 Crispr-associated protein Cas1 n=5 Tax=Francisel...    50   1e-04
UniRef50_Q5LZX6 Putative uncharacterized protein n=2 Tax=Strepto...    50   1e-04
UniRef50_A2SQK9 Uncharacterized protein predicted to be involved...    50   1e-04
UniRef50_C7XMU1 CRISPR-associated protein cas1 n=2 Tax=Fusobacte...    49   2e-04
UniRef50_D1VVR4 CRISPR-associated endonuclease Cas1, DVULG subty...    49   2e-04
UniRef50_A8TI31 CRISPR-associated protein Cas1 n=1 Tax=Methanoco...    49   2e-04
UniRef50_P71636 CRISPR-associated protein Cas1 n=11 Tax=Mycobact...    48   4e-04
UniRef50_B2UP48 CRISPR-associated protein Cas1 n=1 Tax=Akkermans...    48   5e-04
UniRef50_UPI00016B206F hypothetical protein cdiviTM7_00753 n=1 T...    48   6e-04
UniRef50_A8LN06 CRISPR-associated protein Cas1 n=2 Tax=Rhodobact...    48   6e-04
UniRef50_C8N6V7 Putative uncharacterized protein n=1 Tax=Cardiob...    47   8e-04
UniRef50_A6DE79 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Cami...    47   0.001
UniRef50_A6VLA8 CRISPR-associated protein Cas1 n=13 Tax=Proteoba...    47   0.001
UniRef50_A9AX66 CRISPR-associated protein Cas1 n=1 Tax=Herpetosi...    47   0.001
UniRef50_C9RJP2 CRISPR-associated protein Cas1 n=21 Tax=cellular...    46   0.001
UniRef50_C0WE67 Crispr-associated protein n=1 Tax=Acidaminococcu...    45   0.002
UniRef50_B0VHC1 Putative uncharacterized protein n=1 Tax=Candida...    45   0.002
UniRef50_C7G696 CRISPR-associated protein Cas1 n=2 Tax=Roseburia...    45   0.003
UniRef50_Q03JI7 CRISPR-associated protein, Cas1 family n=40 Tax=...    45   0.003
UniRef50_D0WRI5 CRISPR-associated protein Cas1, NMENI subtype n=...    45   0.004
UniRef50_B3DR65 Putative uncharacterized protein n=1 Tax=Bifidob...    45   0.005
UniRef50_B9CMG3 CRISPR-associated protein Cas1, NMENI subtype n=...    44   0.005
UniRef50_UPI000174611D CRISPR-associated protein Cas1/Cas4 n=1 T...    44   0.006
UniRef50_C2EF73 CRISPR-associated Cas1 family protein n=1 Tax=La...    44   0.007
UniRef50_D1AUW5 CRISPR-associated protein Cas1 n=1 Tax=Streptoba...    44   0.008
UniRef50_C8PNV3 CRISPR-associated protein Cas1 n=1 Tax=Treponema...    43   0.013
UniRef50_B8I084 CRISPR-associated protein Cas1 n=1 Tax=Clostridi...    42   0.024
UniRef50_A9GQD8 Putative uncharacterized protein n=1 Tax=Sorangi...    40   0.080

>UniRef50_Q46896 Uncharacterized protein ygbT n=119 Tax=cellular organisms
           RepID=YGBT_ECOLI
          Length = 305

 Score =  428 bits (1100), Expect = e-118,   Method: Composition-based stats.
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60
           MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV
Sbjct: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60

Query: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120
           SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF
Sbjct: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120

Query: 121 ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180
           ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI
Sbjct: 121 ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP 240
           SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP
Sbjct: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP 240

Query: 241 GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA 300
           GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA
Sbjct: 241 GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA 300

Query: 301 GHRSS 305
           GHRSS
Sbjct: 301 GHRSS 305


>UniRef50_D1A5U2 CRISPR-associated protein Cas1 n=3 Tax=Actinomycetales
           RepID=D1A5U2_THECD
          Length = 315

 Score =  391 bits (1005), Expect = e-107,   Method: Composition-based stats.
 Identities = 105/297 (35%), Positives = 155/297 (52%), Gaps = 7/297 (2%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + DR+S I+L+   +   D A    D  GI THIP  ++ C++L PGTRV+H A
Sbjct: 12  PRELTRMSDRISFIYLERCTLHREDNAITAEDADGI-THIPSATIGCLLLGPGTRVTHQA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + +    G  +VWVGE GVR Y+ G+     S  +  QA    +   RL+V R M+ +RF
Sbjct: 71  MSVLGDSGAGVVWVGEQGVRFYSGGRSLTRSSALVEAQAIKWANRRTRLEVARAMYRMRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +  PA  + ++L G EG RV+  Y   A +YG+TW GR Y P D+   D +NQ ++AA 
Sbjct: 131 PDEDPAGLTRQELLGREGRRVKERYRQEAAKYGITWKGRHYIPGDFGSSDPVNQAVTAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C+YG+ +  + A G +P +GF+H+G  L+FV DIAD+ K +  +P AF     +P +  
Sbjct: 191 QCMYGIAQTTVAALGCSPGLGFIHSGHELAFVLDIADLYKTEFALPIAFRTVAESPEDVG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAG 301
              R A RD       L + +  I+ +L       P  P+D     I      GD G
Sbjct: 251 SRTRRAIRDEVNRVGLLRRCVDDIKSLLL------PDVPDDPLNSDIDQVTLQGDHG 301


>UniRef50_D1NTI3 CRISPR-associated protein Cas1 n=10 Tax=Bacteria RepID=D1NTI3_9BIFI
          Length = 366

 Score =  384 bits (987), Expect = e-105,   Method: Composition-based stats.
 Identities = 106/296 (35%), Positives = 162/296 (54%), Gaps = 4/296 (1%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVR 66
             +  +DR++ ++ ++  ++  + A  + D  G+R HIP  +++ +ML PGT V+H A+ 
Sbjct: 32  ELVRCEDRLTFLYFEHCVVNRDNNAITVTDDRGVR-HIPAAALSVLMLGPGTSVTHQAMM 90

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
           +    G  ++WVGE GVR Y SG+P    S+ L  QA+L  +   RL V R M+ +RF  
Sbjct: 91  VIGDNGATVIWVGERGVRTYCSGKPLTHSSNLLQKQAQLVTNMRKRLSVARAMYAMRFPH 150

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
              +  +++QLRG EG+RVR  Y   +KQ GV W  R Y P+D+   D INQ +SAA  C
Sbjct: 151 EDVSNLTMQQLRGREGARVRRVYRHWSKQTGVRWERRDYRPEDFADSDRINQALSAANIC 210

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDRE 246
           LYG+  A I+A G +P +GFVHTG  LSFVYD+AD+ K +  +P AF+ A     +    
Sbjct: 211 LYGIAHAVIVALGCSPGLGFVHTGHELSFVYDMADLYKAELSIPVAFKTAATEVDDIGGA 270

Query: 247 VRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP---EDAQPVAIPLPVSLGD 299
           VR A RD       + +++  I  +  A + +         D +   +    S GD
Sbjct: 271 VRRAMRDAMYDLSIMPRMVKDIHHLFDAADAENEGNNLYLWDGKEGTVEAGRSYGD 326


>UniRef50_Q2JWC7 CRISPR-associated protein Cas1 n=3 Tax=Chroococcales
           RepID=Q2JWC7_SYNJA
          Length = 315

 Score =  383 bits (983), Expect = e-105,   Method: Composition-based stats.
 Identities = 112/299 (37%), Positives = 175/299 (58%), Gaps = 6/299 (2%)

Query: 6   LNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           L  IP ++D +S ++++  +I+    A  ++ + G R  IP  S+  +ML PGT ++HAA
Sbjct: 10  LRSIPKVRDSISFVYVERCRIEQDAKAIAVLQEDG-RYIIPCASLTTLMLGPGTAITHAA 68

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           ++  A     + WVGE G+R YASG    +  ++L +QAKL  D    ++VVR+M+  RF
Sbjct: 69  IKNLADGLCSVQWVGEDGLRFYASGSHPSSSVERLYHQAKLWADPVQHMEVVRRMYSFRF 128

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            EP     ++EQ+RG+EG RVR  Y+ L+K+ GV W GR Y  K+WE  D +N+ +S A 
Sbjct: 129 PEPLKEGLTLEQIRGLEGVRVRTVYSRLSKETGVNWKGRSYKLKEWECADPVNRALSVAN 188

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           +CLY V +AA+ A GY+ A+GF+H GKPLSFVYD+AD+ K +  +P AF+ A       +
Sbjct: 189 TCLYAVCQAALNAVGYSTALGFIHIGKPLSFVYDVADLYKTEITIPVAFKAAAELMPNFE 248

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVSLGD 299
              R  CR+ F   + + ++I  ++ +L     Q  + P     D +  A+   VS G+
Sbjct: 249 SRTRQLCREKFVEHRLMQRIIDDVDAILGFRATQEESSPVGSLWDNEKGAVEGGVSYGE 307


>UniRef50_C7QEM2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria RepID=C7QEM2_CATAD
          Length = 323

 Score =  380 bits (975), Expect = e-104,   Method: Composition-based stats.
 Identities = 95/279 (34%), Positives = 152/279 (54%), Gaps = 1/279 (0%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + DRVS ++L+   +     A    D  GI THIP  ++  ++L PGTR++H A
Sbjct: 12  PYQLPRIADRVSFVYLERCTVHRDANAITAQDADGI-THIPSATIGTLLLGPGTRITHQA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + +    G  + WVGE G R YA+ +     S  +  QA L  +   RL + R M+ +RF
Sbjct: 71  MAVLGDCGANVAWVGEHGARFYAAARSLNRSSALVEAQATLWANRRTRLDIARAMYRMRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +  P+    +QL G+EG R++  Y   +++ GV W+GR+Y P ++  GD INQ I+AA 
Sbjct: 131 PDEDPSGFMRQQLLGMEGRRLKDCYRQQSQRTGVPWHGRQYTPGNFNAGDAINQAITAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C+YGV    I A G +P +GF+H+G  LSFV DIAD+ K +  +P AF+ A  +  +  
Sbjct: 191 QCMYGVAHTIITALGCSPGLGFIHSGHELSFVMDIADLYKTEIGIPVAFDTAAEDSTDIG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP 283
              R A R+  R+++ L + +  ++ +L     +P +  
Sbjct: 251 PRTRRALREQIRTTRLLERCVDDVKALLTTPNNEPGSSD 289


>UniRef50_D1CAI8 CRISPR-associated protein Cas1 n=3 Tax=Bacteria RepID=D1CAI8_SPHTD
          Length = 314

 Score =  373 bits (958), Expect = e-102,   Method: Composition-based stats.
 Identities = 117/288 (40%), Positives = 175/288 (60%), Gaps = 6/288 (2%)

Query: 4   LPLNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           + L+ +P ++D  S +++++ +I+    A  + D  G+   +P  S+  +ML PGT +SH
Sbjct: 1   MDLHILPKVRDSWSYLYVEHARIEQEAKAIAIHDAVGM-VPVPCASLGILMLGPGTSISH 59

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
           AA+R  A+ G L++W GE GVR YA G      +  L+ QA+L  D  LRL+VV +M+++
Sbjct: 60  AAIRTLAENGCLVLWTGEEGVRFYAQGLGETRSARNLMRQARLWADPALRLRVVFRMYQM 119

Query: 123 RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISA 182
           RF EP P   +++Q+RG+EG+RVR  YA  +++ GV W GR +  ++W   D IN+ +S 
Sbjct: 120 RFSEPLPPDLTLQQIRGMEGARVRDAYARASRETGVPWRGRSFQRRNWSATDPINRALSC 179

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           A SCLYG+  AAI++ GY+P +GF+HTGK LSFVYDIAD+ K    +P AF +      +
Sbjct: 180 ANSCLYGICHAAIVSLGYSPGLGFIHTGKMLSFVYDIADLYKATVTIPLAFRVVAEGTHD 239

Query: 243 PDREVRLACRDIFRSSKTLAKLIPLIEDVL----AAGEIQPPAPPEDA 286
            +  VR ACRD F + + L  +   IE VL    A G    P   EDA
Sbjct: 240 LEGRVRRACRDAFVAHRLLGTIATDIEHVLDISDADGGADEPDFDEDA 287


>UniRef50_D1CGD6 CRISPR-associated protein Cas1 n=7 Tax=cellular organisms
           RepID=D1CGD6_THET1
          Length = 324

 Score =  371 bits (952), Expect = e-101,   Method: Composition-based stats.
 Identities = 125/299 (41%), Positives = 177/299 (59%), Gaps = 5/299 (1%)

Query: 1   MTWLPLNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTR 59
           M    L+ +P + D  S +++++ +ID    A  L D TG +T +P  S++ +ML PGT 
Sbjct: 1   MRLKDLHILPRVSDSWSYLYVEHCRIDQDARAISLHDATG-KTMVPCASLSLLMLGPGTS 59

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM 119
           ++HAA++  A  G L+ WVGE GVR YA G      +   L QA L  D +L L+VVR+M
Sbjct: 60  ITHAAIQTLADNGCLVAWVGEEGVRFYAQGMGETRSATNTLRQAMLWSDPELHLQVVRRM 119

Query: 120 FELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQC 179
           +E+RF  P     S++Q+RG+EG+RVR  Y  L+++ GV W GR Y  K W   D IN+ 
Sbjct: 120 YEIRFRHPINPNTSLKQIRGMEGARVRGAYLQLSRETGVEWKGRDYSSKSWHSNDAINRA 179

Query: 180 ISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRN 239
           ISAA SCLYGV  AAI++AGY+ A+GF+HTGK LSFVYD+AD+ K +  +P AF      
Sbjct: 180 ISAANSCLYGVCHAAIVSAGYSTALGFIHTGKMLSFVYDVADLYKTEISMPAAFYAVAEG 239

Query: 240 PGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLG 298
               +  VR  CRDI R ++ LA+++  I+ VL    +  P P +   P      V  G
Sbjct: 240 GASLESRVRRKCRDILRETRLLARIVEDIDTVL---NVDSPIPHKYQNPYDSDPGVPGG 295


>UniRef50_D2RB04 CRISPR-associated endonuclease Cas1, ECOLI subtype n=3 Tax=Bacteria
           RepID=D2RB04_GARVA
          Length = 313

 Score =  370 bits (951), Expect = e-101,   Method: Composition-based stats.
 Identities = 105/296 (35%), Positives = 165/296 (55%), Gaps = 7/296 (2%)

Query: 10  PLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
            + DRVS I++++ +I+ +D A  + D  G    +P   +  ++L PGT ++H A+ L  
Sbjct: 17  RISDRVSFIYVEHAKINRLDSAVTVFDANGT-IRVPAAMIGVLLLGPGTEITHRAMELLG 75

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP 129
            VG  +VWVGE GVR YA G+     S  L  Q+KL  +   RL V RKM+++RF     
Sbjct: 76  DVGASIVWVGEHGVRNYAHGRALSRSSRLLEKQSKLVTNSRSRLNVARKMYQMRFPNENV 135

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
           +  +++QLRG EG+RVR  Y  ++ +Y V WNGR Y   D+E G  +N+ +S    CLYG
Sbjct: 136 SSYTLQQLRGREGARVRHLYREMSNKYNVQWNGRDYKVNDFESGTVVNKALSVGNVCLYG 195

Query: 190 VTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP--DREV 247
           +  + I A G AP +GFVHTG  LS VYDIAD+ K +  +P +FEIA R   +   ++ +
Sbjct: 196 LVHSIISALGLAPGLGFVHTGHDLSLVYDIADLYKAELTIPASFEIAARCESDDDIEQLM 255

Query: 248 RLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVSLGD 299
           RL  RD F +   +++++  I+++L                D + + +   V+  +
Sbjct: 256 RLKMRDCFANCNIMSRIVNDIQNLLEIPIDDQITVDVIHLWDDKELLVASGVNYSE 311


>UniRef50_B4V4P5 Crispr-associated protein cas1 n=4 Tax=Streptomyces
           RepID=B4V4P5_9ACTO
          Length = 315

 Score =  368 bits (946), Expect = e-101,   Method: Composition-based stats.
 Identities = 97/281 (34%), Positives = 149/281 (53%), Gaps = 1/281 (0%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + +R+S ++L+   +     A    D  G  THIP  ++  ++L PGTR++H A
Sbjct: 12  PRELTRVAERISFVYLERCVVHRDANAITAEDADGT-THIPSATIGTLLLGPGTRITHQA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + + A+ G  + WVGE GVR YA G+     S  +  QA L  +   RL+V R M+ LRF
Sbjct: 71  MSVLAESGAAVAWVGEQGVRYYAGGRALSRSSALVEAQATLWANRRTRLEVARAMYRLRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +  P+  +  +L G EG RV+  Y   A + GV W GR Y P D+  GD  NQ ++AA 
Sbjct: 131 PDEDPSGLTRRELLGHEGYRVKECYRHQADRTGVPWRGRHYVPGDFTAGDAPNQAVTAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C+YG+  A + A G A  +GFVH+G  LSFV D+AD+ K +  +P AF++A  +  +  
Sbjct: 191 QCMYGIAHAVVAALGCATGLGFVHSGHELSFVLDVADLYKTEIGIPVAFDVAAESTEDIG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPED 285
              R A RD    ++ L + +  I+ +L        +  +D
Sbjct: 251 SRTRRALRDAVNKNRLLDRCVNDIKLLLQPEGPGAASAADD 291


>UniRef50_C1YVP5 CRISPR-associated protein Cas1 n=1 Tax=Nocardiopsis dassonvillei
           subsp. dassonvillei DSM 43111 RepID=C1YVP5_NOCDA
          Length = 327

 Score =  367 bits (943), Expect = e-100,   Method: Composition-based stats.
 Identities = 102/302 (33%), Positives = 148/302 (49%), Gaps = 6/302 (1%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + +R+S ++L+   +     A    D  G R  +P  ++  ++L PGT V+H+A
Sbjct: 12  PRELTRVGERLSFLYLERCVVHRDSNAITAEDGDGTRY-LPSATIGTLLLGPGTNVTHSA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + L  + G  +VWVGE GVR YA+G+     S  +  QA    +   RL V R M+ +RF
Sbjct: 71  MSLLGECGATVVWVGEHGVRYYAAGRALTRSSRLVEAQATAWANRRSRLDVARAMYRMRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +      S + L G EG RV+A Y   A + GVTW GRRY P D +  D  N+ I+AA 
Sbjct: 131 PDLDVEALSRQALLGKEGDRVKACYREQAARTGVTWRGRRYVPGDHDVSDPPNKAITAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C YGV  A   A G +P +GFVH+G    FV D+AD+ K +  +P AF+ A +   + D
Sbjct: 191 QCFYGVAHAVTAALGCSPGLGFVHSGHERGFVMDVADLYKVEIGIPVAFDAAAQGDEDVD 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIED-VLAAGEIQPPAPPEDAQPVAIPLPV----SLGD 299
              R   RD       L + +  I+  +L  G +      EDA   A          +GD
Sbjct: 251 GVTRRLLRDRINEEGLLERCVRDIKALLLGEGSVGAQGEAEDAGESANDDVADTVGLVGD 310

Query: 300 AG 301
            G
Sbjct: 311 RG 312


>UniRef50_Q3ZZ81 CRISPR-associated protein Cas1 n=4 Tax=Bacteria RepID=Q3ZZ81_DEHSC
          Length = 309

 Score =  365 bits (936), Expect = 1e-99,   Method: Composition-based stats.
 Identities = 118/280 (42%), Positives = 179/280 (63%), Gaps = 2/280 (0%)

Query: 6   LNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           L+ +P  +DR S ++L+ G++DV   +     +      +P+  +  +ML PG+ V+HAA
Sbjct: 4   LHELPRFRDRWSYLYLEMGRLDVEADSL-GFHQGDTVVPVPIDQLGVVMLGPGSTVTHAA 62

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           ++  +Q   L+ W G+ GVR+YA+   G   + +L+ QA+L  D++ RL+V  +M+  RF
Sbjct: 63  IKSLSQNNCLIAWTGQDGVRLYAASIGGTYSARRLIRQARLVSDDEKRLEVAWRMYRFRF 122

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            E  P   S+E +RG+EG RVR  YA  +++YGV W GR YD KDW KGD IN+ +SAA 
Sbjct: 123 NEVIPPVVSLESIRGMEGIRVRRAYAKASQEYGVEWKGRHYDQKDWSKGDPINRALSAAN 182

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           +CLYG+  A IL+AGY+ A+GFVHTGK LSFVYD+AD+ K +  +P AF++A  NP + +
Sbjct: 183 ACLYGICHAGILSAGYSSALGFVHTGKMLSFVYDVADLYKTELTIPVAFKVAAANPTDLE 242

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPE 284
           R+VR+ CR+ F   K L +L+  I +VL   +    +P E
Sbjct: 243 RQVRIECREAFYEFKLLERLLTDIAEVLGVSDDIGESPDE 282


>UniRef50_A8M406 CRISPR-associated protein Cas1 n=5 Tax=Actinomycetales
           RepID=A8M406_SALAI
          Length = 322

 Score =  359 bits (922), Expect = 6e-98,   Method: Composition-based stats.
 Identities = 114/288 (39%), Positives = 160/288 (55%), Gaps = 5/288 (1%)

Query: 10  PLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
             +DR+S ++L+   I     A    D+ GI  HIP  ++  +ML PGT ++  A+ L A
Sbjct: 16  RAQDRISFVYLERCVIHRDSNAITATDEKGI-VHIPAATLGVLMLGPGTSITQQAMMLIA 74

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP 129
             G  +VW+GE GVR YA G+P    S  L+ QA      D RL+V R M+ +RF     
Sbjct: 75  DNGATVVWIGEHGVRYYAHGRPLARSSRLLVAQAAAVSHRDRRLRVARAMYRMRFPGEDT 134

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
              +++QLRG EG+RVR  Y   A++ GV+WN R YDP D+   D +NQ +SAA +CLYG
Sbjct: 135 TNLTMQQLRGKEGARVRRCYRENAQRTGVSWNSREYDPDDFTGSDPVNQALSAAHACLYG 194

Query: 190 VTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRL 249
           +  A ++A G +P +GFVHTG   SFVYDIAD+ K D  +P AF+IA     +   + R 
Sbjct: 195 IVHAVVVAVGASPGLGFVHTGHDRSFVYDIADLYKADVTIPVAFDIAAAESTDIGADTRR 254

Query: 250 ACRDIFRSSKTLAKLIPLIEDVL----AAGEIQPPAPPEDAQPVAIPL 293
           A RD   +   L + +  I  +L    AAG I      E+A   A+ L
Sbjct: 255 AVRDRVHNGALLGRCVQDIRRLLLTDSAAGPINEEEFDEEADNDAVRL 302


>UniRef50_C7LYW4 CRISPR-associated protein Cas1 n=1 Tax=Acidimicrobium ferrooxidans
           DSM 10331 RepID=C7LYW4_ACIFD
          Length = 314

 Score =  357 bits (917), Expect = 3e-97,   Method: Composition-based stats.
 Identities = 98/277 (35%), Positives = 158/277 (57%), Gaps = 1/277 (0%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVR 66
              P+  R S ++L++  +     A V + ++G  T++P  +V  ++L PGTR++H A+ 
Sbjct: 17  ELQPVSRRSSFVYLEHCVVHRDANAVVSVTESGT-TYLPAAAVGTLLLGPGTRITHQAML 75

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
           L  + G ++ WVGE   R+YA        +  L  QA+L  +   RL+V R+M+++RF  
Sbjct: 76  LLGESGVVVCWVGEGDTRLYAWAPSLFQSTRFLEAQARLVSNRQDRLRVARQMYQMRFPG 135

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
              ++ ++++LRG+EG+R+R TY  LA  +G+ W+GR YDP +   GD +N+ +S A S 
Sbjct: 136 EDVSKATMQRLRGMEGARIRRTYRHLASAFGIDWHGRHYDPNNSSAGDDVNRALSIANSV 195

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDRE 246
           LYGV   AI+A G +P +GFVHTG  LSFVYD+AD+ K +  +P AFE A +  G    +
Sbjct: 196 LYGVVHTAIVALGCSPGLGFVHTGHSLSFVYDVADLYKVELAIPVAFEAAAQRTGSLSSQ 255

Query: 247 VRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP 283
           VR   R+    +  L + +  I  +L   +      P
Sbjct: 256 VRRTMRERIHEAHLLERAVDDIRLLLGTPDADLGGEP 292


>UniRef50_B1VIX8 CRISPR-associated protein n=6 Tax=Corynebacterium
           RepID=B1VIX8_CORU7
          Length = 312

 Score =  355 bits (911), Expect = 1e-96,   Method: Composition-based stats.
 Identities = 93/269 (34%), Positives = 154/269 (57%), Gaps = 1/269 (0%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           + DR+S ++++   +     A  + D+ G+  H+P   +A ++L  GTR+++AA+ L   
Sbjct: 17  MGDRISFLYVERAVVSRDGNALTITDQRGV-AHVPATQLAVLLLGTGTRITNAAMALLGD 75

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            G   VWVGE GVR YA G+P    S     QA++  ++  RL+  R+M+ LRF     +
Sbjct: 76  CGVSTVWVGERGVRYYAHGRPPAKSSRLAELQARVVTNQRKRLECARRMYGLRFPGEDVS 135

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
           + ++ QLRG EG+R++  YA  AK+ GV WN RRYDP D++  D INQ ++  ++ LYG+
Sbjct: 136 KLTMAQLRGREGARMKRLYAAEAKRTGVAWNRRRYDPNDYDSSDPINQALTTGSAALYGI 195

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
             A I+  G+ PA+G +HTG   SFVYD+AD+ K +  +P AF        +    VR  
Sbjct: 196 AHAVIVGLGFVPALGVIHTGTDRSFVYDVADLYKAEVSIPAAFNAVASGTEDVGPMVRRL 255

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
            RD     + + +++  ++ V++  + +P
Sbjct: 256 VRDAVVEQRLMPRMVRDLKFVMSVPDDEP 284


>UniRef50_C7MTM5 CRISPR-associated protein, Cas1 family n=6 Tax=Actinomycetales
           RepID=C7MTM5_SACVD
          Length = 342

 Score =  342 bits (877), Expect = 9e-93,   Method: Composition-based stats.
 Identities = 112/300 (37%), Positives = 169/300 (56%), Gaps = 7/300 (2%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P +   L DRVS ++++   +D  + A  +I++      +P   VA ++L PGTRV+H A
Sbjct: 12  PHDLHRLTDRVSSVYIERSHLDRAENAIAIINRRET-VRLPAALVAVVLLGPGTRVTHGA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           ++L A  GT + WVGE GVR+YA+G      +  L  QA L      RL+V R M+ +RF
Sbjct: 71  MQLLADSGTAVCWVGEQGVRMYAAGLGPSRGAALLQRQAYLVSRTTTRLEVARAMYAMRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD-WEKGDTINQCISAA 183
                +  +++QLRG EG+RVR  Y   A+Q+GV WNGR Y   D +  GD +N+ +SAA
Sbjct: 131 PGEDVSTLTMQQLRGREGARVRKVYRQQARQHGVPWNGRAYKAGDAFAVGDDLNRLLSAA 190

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            + LYG+  A I+  G +P +GF+HTG   SFV DIAD+ K +  +P AF++A R   E 
Sbjct: 191 NAALYGICHAVIVGLGASPGLGFIHTGSATSFVMDIADLYKAEYTIPLAFQLAARGLLE- 249

Query: 244 DREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVSLGD 299
           +R+ R A RD    +  L ++I  ++ +LA   +  P P      D +   +P  V+  D
Sbjct: 250 ERDARTALRDRIAGTGLLPRIIKDVKTLLAPEGVDLPDPEVNLLWDERGNPVPGGVNWSD 309


>UniRef50_Q03C58 CRISPR-associated protein n=3 Tax=Lactobacillus RepID=Q03C58_LACC3
          Length = 315

 Score =  341 bits (875), Expect = 2e-92,   Method: Composition-based stats.
 Identities = 102/265 (38%), Positives = 161/265 (60%), Gaps = 3/265 (1%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVR 66
               +++RV+ ++L++ +I+  D A V+ID TG    IP   ++ +ML PG  V+H A+ 
Sbjct: 12  ELSRVRERVTFLYLEHAKINRQDSAIVVID-TGGTVAIPAALISVLMLGPGVDVTHRAME 70

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
           L    G  +VWVGE GVR YA G+     S  L+ QAKL  +  LR+ V R+M+++RF +
Sbjct: 71  LMGDAGMSVVWVGERGVRQYAPGRALTHSSALLVAQAKLVSNNRLRVGVARQMYQMRFPD 130

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
              +  S+++LRG EG+RVR  Y   +++ GV W  R YDP++++ G  INQ ++AA + 
Sbjct: 131 DDVSTLSMQELRGKEGARVRRIYREESRRTGVEWTHREYDPENYQSGSIINQALTAAHAA 190

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIA--RRNPGEPD 244
           LYG++ + I+A G +P +GFVHTG  LSFVYD AD+ K +  +P AF +A       +  
Sbjct: 191 LYGLSYSVIVALGASPGLGFVHTGHDLSFVYDFADLYKAEVTIPIAFTVAANATEQDDIG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIE 269
           +  RLA RD F   K + +++  ++
Sbjct: 251 QLTRLAVRDAFVDGKLMIRMVADLK 275


>UniRef50_C2BS02 CRISPR-associated protein n=1 Tax=Mobiluncus curtisii ATCC 43063
           RepID=C2BS02_9ACTO
          Length = 314

 Score =  339 bits (869), Expect = 8e-92,   Method: Composition-based stats.
 Identities = 87/270 (32%), Positives = 148/270 (54%), Gaps = 1/270 (0%)

Query: 10  PLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
            ++DR+S ++++   ++    A  + D  GI  HIP   V  ++L PGT+V++AA+ L  
Sbjct: 17  RMEDRLSFLYVERAILNREGNALTIQDSRGI-AHIPATQVGVVLLGPGTKVTYAAMALLG 75

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP 129
             G   VWVGE GVR YA G+P    S      A+L  ++  RL+  R+M+ +RF     
Sbjct: 76  DAGCSAVWVGEKGVRYYAHGRPAAKTSRMAEAHARLWANQRSRLRCARRMYSMRFPGEDV 135

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
           +   + QLRG EG+R++  YA  +++ GV W  R YDP D+  GD IN  ++   + LYG
Sbjct: 136 SNLPLSQLRGREGARMKRIYAEQSRRTGVPWTRRSYDPNDFGAGDPINCALTEGAAALYG 195

Query: 190 VTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRL 249
           +  A ++  G+ P++G +H+G   +FVYD+AD+ K +  +P AFE    +    +  VR 
Sbjct: 196 IAHAVVVGLGFIPSLGIIHSGTDRAFVYDVADLYKAEISIPAAFEAVAASAEGDELNVRK 255

Query: 250 ACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
             RD   +++ + +++  ++ V+       
Sbjct: 256 RIRDKVVTTRLMQRMVRDLQYVMEIPTDDA 285


>UniRef50_C7MTL6 CRISPR-associated protein, Cas1 family n=4 Tax=Actinomycetales
           RepID=C7MTL6_SACVD
          Length = 328

 Score =  338 bits (868), Expect = 1e-91,   Method: Composition-based stats.
 Identities = 96/292 (32%), Positives = 160/292 (54%), Gaps = 12/292 (4%)

Query: 10  PLKDRVSMIFLQYGQIDVID-GAFVLI---DKTGIRTHIPVGSVACIMLEPGTRVSHAAV 65
            + D +S ++L+  ++   D G    +   D    R ++PV +++CI+   GT V+  A+
Sbjct: 22  RVADSLSFLYLENVRVVQDDTGVCAYVEQPDGGTSRVYLPVAAISCILFGTGTSVTQPAM 81

Query: 66  RLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG 125
              A+  T ++W G  GVR+Y+        ++ L  Q +   D+  RL V  +M+ +RFG
Sbjct: 82  ATCARHNTTVLWTGSGGVRMYSGSLAPNLTTEWLERQVRAWADDSTRLAVAARMYSMRFG 141

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
              PA  S+  LRG+EG R++A Y  LA ++G+    R YDP +W + + +NQ +SAA +
Sbjct: 142 AEVPAGTSLNTLRGLEGQRMKALYRSLADRHGLRGFKRNYDPANWGEQNPVNQALSAANT 201

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDR 245
            LYG   +A+LA G +PA+GF+H+GK  SFVYD+AD+ K    +P AF + +    +PDR
Sbjct: 202 ALYGAVHSALLALGCSPALGFIHSGKQHSFVYDVADLYKAKHTIPLAFALHKS--AQPDR 259

Query: 246 EVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSL 297
           EVR+  R  F   + + +++  ++ +L       P+  +D      P  V L
Sbjct: 260 EVRIRMRQDFHLYRLMPRIVRDVQRLL------DPSIAQDHDETGEPEEVEL 305


>UniRef50_C4X9I5 CRISPR-associated Cas1 family protein n=12 Tax=Bacteria
           RepID=C4X9I5_KLEPN
          Length = 294

 Score =  313 bits (802), Expect = 5e-84,   Method: Composition-based stats.
 Identities = 92/274 (33%), Positives = 147/274 (53%), Gaps = 2/274 (0%)

Query: 6   LNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
              +P +KD+   ++L+ G++++ D +   +D  G    +PV ++  ++L PGT V+H A
Sbjct: 16  RELLPQVKDKYPFLYLERGRLEIDDSSVKWVDADGNVVPLPVATINTLLLGPGTTVTHEA 75

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           ++ A      + WVGE  +  YA+G    A +  L  Q  LA D    LKV R MF  RF
Sbjct: 76  IKTATAANCAVCWVGEDSLLFYAAGFLPTADTRNLKAQMALACDASSTLKVARAMFAKRF 135

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +     +S+  + G+EGSRVRA Y   A++YGV W GR++ P  +E  D  NQ +++  
Sbjct: 136 PDADLEGKSLNSMMGMEGSRVRALYQQKAQEYGVGWKGRQFTPGKFELSDLTNQVLTSTN 195

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           + LYG+  + + A GY+P IGF+H+G PL FVYD+AD+ K    +  AF ++R   G  D
Sbjct: 196 AALYGILCSVVHAMGYSPHIGFIHSGSPLPFVYDLADLYKERLCIDLAFSLSREMAGRYD 255

Query: 245 RE-VRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           +  V  A R    +   L  +   I +++     
Sbjct: 256 KHKVSEAFRKRVIALDLLNLIAADINELMGGKGA 289


>UniRef50_B6IWM1 CRISPR-associated protein Cas1, putative n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM1_RHOCS
          Length = 281

 Score =  299 bits (766), Expect = 7e-80,   Method: Composition-based stats.
 Identities = 86/275 (31%), Positives = 136/275 (49%), Gaps = 6/275 (2%)

Query: 4   LPLNPIPLKDRVSMIFLQYGQIDVIDGAFVL-IDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           L    IP K R  +I+++  ++ + +G+ V+  D  G    +P   +  ++L PG+ ++H
Sbjct: 8   LDAARIPQKSRNGLIYVERCRLSIDNGSLVIAFDDRGEELELPYQRLNAVLLGPGSSITH 67

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
            AVR  +  GT L +VG  G R+Y +       S     QA     E  R+ V ++M+  
Sbjct: 68  DAVRHCSGHGTCLAFVGSDGTRLYTAPPLFDRDSTLARQQATWWAGESTRIMVAKRMYAK 127

Query: 123 RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISA 182
           RFGE  P   S++ LRG+E +R+R +Y L+A Q G+ W GRR+D  D +  D  NQ I+ 
Sbjct: 128 RFGE-TPRATSLDSLRGMEAARIRHSYELIAAQAGIVWRGRRFDRSDPDGDDLPNQAINH 186

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR---- 238
             + +      A+ A G  P +GF+H     S+  DI D+ +    VP AF   +R    
Sbjct: 187 VVTAVEACVAIAVQATGTLPPLGFLHEDSAKSWTLDICDLYRTSVTVPLAFRCVKRIDQG 246

Query: 239 NPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
                DR  R A     R +  +  +I  I++VLA
Sbjct: 247 ATDSLDRICRRAVSAHVRDTGFIDTIIDDIKEVLA 281


>UniRef50_C9M9R9 CRISPR-associated protein Cas1 n=1 Tax=Jonquetella anthropi E3_33
           E1 RepID=C9M9R9_9BACT
          Length = 281

 Score =  299 bits (766), Expect = 8e-80,   Method: Composition-based stats.
 Identities = 97/272 (35%), Positives = 145/272 (53%), Gaps = 10/272 (3%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTH-----IPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           M++L+ G + V DG    +   G         IP  +V+ I+LEPGT ++H   RL  Q 
Sbjct: 1   MLWLERGNLFVKDGTLRFVSAGGGSLEKGTYDIPYQNVSMIVLEPGTTITHDVFRLMGQQ 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPAR 131
           GT L+ VG+ GVR Y +   G  RS     Q +L  +   RL+V   M+ +RFGE  P R
Sbjct: 61  GTGLIAVGDKGVRCYTAPPLGPDRSALARRQVELWANPQTRLQVALAMYAIRFGEELPTR 120

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
           + +E LRGIEG+R+R +Y++LAK YG+TW  RR++ K   K D IN  ++ A S +YG  
Sbjct: 121 K-IEDLRGIEGARLRKSYSILAKFYGLTWTLRRFNRKQPNKTDDINAAVNHAASAMYGAA 179

Query: 192 EAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP----DREV 247
           + A+ A    P +GFVH     +F  DIAD+ + +  +P AF        EP    +R V
Sbjct: 180 DIAVAAVSAIPQLGFVHAKSCRAFALDIADLYRTEITLPAAFRGLASYLEEPGMDLERHV 239

Query: 248 RLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
           R          K ++K+I  I++++  G+   
Sbjct: 240 RKLIGQELYRQKVISKMIDQIKELILHGQSDE 271


>UniRef50_Q47PJ6 CRISPR-associated protein, Cas1 family n=4 Tax=Actinomycetales
           RepID=Q47PJ6_THEFY
          Length = 332

 Score =  296 bits (757), Expect = 9e-79,   Method: Composition-based stats.
 Identities = 92/310 (29%), Positives = 157/310 (50%), Gaps = 21/310 (6%)

Query: 10  PLKDRVSMIFLQYGQIDVID-GAFVLIDKTGIRTH---IPVGSVACIMLEPGTRVSHAAV 65
            + D +S +++   +I   D G    ++    R H   IP  S+AC++L PGT ++  A+
Sbjct: 18  RVSDGLSFLYVDVCRIVQTDTGVCAEVETETGRIHRVPIPTASLACVLLGPGTSITSPAM 77

Query: 66  RLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG 125
               +  T +V  G  G+  Y S       +  +  QA+   D+  R  V  +M+E+RFG
Sbjct: 78  ATFMRHNTTVVTCGAGGILNYGSFPAPNRTTKWIDRQARAYSDDRRRRDVAVRMYEMRFG 137

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
           E  P   S+E+LR +EG+R++A Y  LA +  V    R Y+P DW+  D +N+ +SA+ +
Sbjct: 138 EEPPPGASIERLRQLEGARMKALYRSLAAKNRVKPFKRNYNPHDWDDQDPVNKALSASNA 197

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDR 245
            LYGV  + +   G  PA+GF+H+GK  +FVYDIAD+ K  T +P AF ++R     P++
Sbjct: 198 ALYGVVHSVLAHLGCHPALGFIHSGKQDAFVYDIADLYKARTTIPLAFSLSRT--ANPEQ 255

Query: 246 EVRLACRDIFRSSKTLAKLIPLIEDVLAAGE----IQPPAPP-----------EDAQPVA 290
           E RL  R   +  + + +++  ++ +L+  +    +    PP            D    A
Sbjct: 256 EARLRLRRDLKLYRLIPQIVRDVQTLLSLDDPEEAVSEEEPPSSGGPWQVVDLWDPVVGA 315

Query: 291 IPLPVSLGDA 300
           +   V+  + 
Sbjct: 316 VSGGVNYANH 325


>UniRef50_Q21QB1 CRISPR-associated protein Cas1 n=1 Tax=Rhodoferax ferrireducens
           T118 RepID=Q21QB1_RHOFD
          Length = 277

 Score =  294 bits (752), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 105/267 (39%), Positives = 154/267 (57%), Gaps = 9/267 (3%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
            K+R+  +FL+ G + V DG  +L+ +      IP   V+C+M+EPG  V+H A++L  +
Sbjct: 17  HKNRIPYLFLEKGILRV-DGHCLLLCQAESAIEIPGSMVSCLMIEPGVSVTHEAMKLCGE 75

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            GTLL+WVGE G R YA+       + ++L QA +  ++  R+    +++ L F +  P 
Sbjct: 76  NGTLLMWVGEGGTRFYAAAHA-HQDASRVLRQAAIHTNQRERIAAASRLYGLMFDDHMPP 134

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
             ++E+LRG+EGSRV+  Y  LA + G+ W GR       E+   +N  I  ATSCLY +
Sbjct: 135 SFTIEKLRGLEGSRVKEIYVNLADKLGMVWQGR-------EEKSALNTSIGFATSCLYAL 187

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
            E AILAAGY P IG VH+G P S V+D+AD +KF TVVP AFEIA  +P   +  VR  
Sbjct: 188 CEVAILAAGYHPGIGVVHSGNPRSLVFDLADTVKFKTVVPLAFEIAATSPSNLNMAVRHG 247

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           CRD+F        L+  +E++      
Sbjct: 248 CRDLFSRESMFETLLGHLENIFGTDHD 274


>UniRef50_Q0AA34 CRISPR-associated protein Cas1 n=11 Tax=Bacteria RepID=Q0AA34_ALHEH
          Length = 298

 Score =  291 bits (744), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 91/279 (32%), Positives = 143/279 (51%), Gaps = 10/279 (3%)

Query: 9   IPLKDRVSMIFLQYGQIDVIDGAFVLI-----DKTGIRTHIPVGSVACIMLEPGTRVSHA 63
           IP  DR  +++L  G++ V DG          D       IP   ++ I+L PG+ V+H 
Sbjct: 18  IPHVDRHGLLWLTRGRLYVEDGTLHFTAAESEDLAAGDYAIPYQGLSMILLGPGSTVTHD 77

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
            +RL A+ GTLL  +G  G + Y +   G  RSD     A L  ++  RL V R+M+  R
Sbjct: 78  VLRLLARHGTLLAAIGGGGTKYYTAPPMGQGRSDVARRHATLWANKTQRLDVARRMYAFR 137

Query: 124 FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
           FG   P  + +  LRGIEG R++  Y + A ++G+ W GRRY+  +    D  NQ I+ A
Sbjct: 138 FGRVLPH-KDIAVLRGIEGGRIKELYRVEASRFGIPWKGRRYNRNNPSAADVPNQAINHA 196

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            + +    + A+ A G  P +GF+H     +F  DIAD+ + +  VP AF+ AR+   +P
Sbjct: 197 ATFVEAAADIAVAATGALPPLGFIHEESSNAFTLDIADLYRGEITVPLAFQAARKVLDDP 256

Query: 244 ----DREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
               +R +R      F+  K + K+I  I+D++ A +  
Sbjct: 257 TLSIERTLRRDAASAFQRHKVIPKMIDRIKDLINADDNG 295


>UniRef50_C2KP50 CRISPR-associated Cas1 family protein n=5 Tax=Actinomycetales
           RepID=C2KP50_9ACTO
          Length = 312

 Score =  278 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 72/278 (25%), Positives = 129/278 (46%), Gaps = 17/278 (6%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVI--------DGAFVLIDKTGIR--THIPVGSVACIMLEP 56
             I L+DRVS ++L+Y Q+           +G     D+  ++    IPV  +A + L P
Sbjct: 17  EQIRLEDRVSYLYLEYCQVIQNHTGVAAISEGNHDSEDREPLKRIIQIPVAGLAVLFLGP 76

Query: 57  GTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVV 116
           GT ++  A+   ++ G  +++ G  G   Y+      + S   + QA L  DE    K  
Sbjct: 77  GTSITQPAMASCSRAGLTVIFSGGGGCPYYSHAMALTSSSRWAIAQAHLVADERNARKAA 136

Query: 117 RKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
           + +++ + G       ++ Q+RG+EGS ++  Y  L++++ V    R     D    D +
Sbjct: 137 KFLYKRQLGIDIERELTISQMRGLEGSLIKKRYRELSREFKVNGFRR-----DTGGEDVL 191

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIA 236
           NQ ++     LYG   +A  A G  PA+G +H G   S ++D+AD+ K +  +P +F   
Sbjct: 192 NQALNLVNGILYGCAASACAALGVNPALGIIHRGDIRSLLFDVADLYKPNAALPISFRSV 251

Query: 237 RRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
            ++  EP +  R   R        L  +I ++ +VL  
Sbjct: 252 SKD--EPLKFARKEMRRFIYEQNVLENMISILMNVLEP 287


>UniRef50_Q3J7J6 CRISPR-associated protein, Cas1 family n=2 Tax=Nitrosococcus oceani
           RepID=Q3J7J6_NITOC
          Length = 295

 Score =  257 bits (657), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 76/294 (25%), Positives = 121/294 (41%), Gaps = 33/294 (11%)

Query: 8   PIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTH---IPVGSVACIMLEPGTRVSHAA 64
           PI    R  + +L++ ++   D   V   + G  T    IP  +   I+L  GT ++ AA
Sbjct: 2   PILPSHRQGLYYLEHCRVMAKDERVVYACQEGAFTKFFAIPPANTNVILLGSGTSLTQAA 61

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR- 123
            RL A    ++ +VG  G  ++ + Q     ++      +L  D D RLKV +     R 
Sbjct: 62  ARLLASEQVMVAFVGGGGSPLFLASQNEYRPTEYCQAWMRLWQDNDQRLKVAKTFQRNRA 121

Query: 124 ---------FGEPAPARRSVE----------QLRGIEGSRVRATYALLAKQYGVTW---- 160
                      EP P + S+E          +L G  G+ + A  A  AK+    W    
Sbjct: 122 EFLMQQWPKLAEPKPHKASLEKLAERYLADIELAGDNGT-ILAQEAKFAKKLYKFWANCT 180

Query: 161 --NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH-TGKPLSFVY 217
                  DP   +  D  N  +      +YG+  A +   G   ++  +H T +  + V+
Sbjct: 181 ETENFTRDPGKRDFNDPFNSYLDHGNYLVYGIAAAVLWVLGIPHSLPVIHGTTRRGALVF 240

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDV 271
           D+ADIIK   V+P AF+ A    G  D+E+R AC      S  +  L   I+ V
Sbjct: 241 DVADIIKDTCVMPIAFQHAA--AGRSDQEMRQACIAWLDESHAMTFLFQSIKRV 292


>UniRef50_C8Q0H7 CRISPR-associated protein Cas1 n=6 Tax=Proteobacteria
           RepID=C8Q0H7_9GAMM
          Length = 334

 Score =  236 bits (601), Expect = 9e-61,   Method: Composition-based stats.
 Identities = 58/302 (19%), Positives = 119/302 (39%), Gaps = 42/302 (13%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKT----GIRTHIPVGSVACIMLEPGTRVSH 62
            P+ L  R  + +L+  ++ + D   V + ++        +IP  + A ++L  G+ ++ 
Sbjct: 27  RPLMLSKRACVFYLERVRVILKDDRIVYLTESMQPIEHFYNIPEKNTAFLLLGKGSSITD 86

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYAS-------GQPGGARSDKLLYQAKLALDEDLRL-- 113
           AA R  A+   ++ + G  G  ++++        Q     ++ +    K  LD+  RL  
Sbjct: 87  AAARRLAESNVMVGFCGSGGSPLFSALDLTFLAPQSEYRPTEYMQIWMKAWLDDTTRLLM 146

Query: 114 ---------KVVRKMFE-----------------LRFGEPAPARRSVEQLRGIEGSRVRA 147
                    ++V+K ++                 + F +   +  + EQL   EG   + 
Sbjct: 147 AKVLLQERIEIVKKYWQKNPLLTSYGIRLDESAVVNFSQAIESAMNQEQLLTAEGRWAKV 206

Query: 148 TYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFV 207
            Y  LA+  G  +        + +  D  N  +       YG    A+   G + A+  +
Sbjct: 207 LYKSLAEGCGFKFTREEGKNANDDIADIANSYLDHGNYIAYGYAAVALHGLGISFALPML 266

Query: 208 HTGKPL-SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIP 266
           H        V+D+AD++K   V+P+AF  A+   G   +E R+   +I +    L  +  
Sbjct: 267 HGKTRRGGLVFDVADLVKDAMVMPQAFISAK--LGHNQKEFRMQLIEICQDQDVLDYMFG 324

Query: 267 LI 268
            +
Sbjct: 325 FV 326


>UniRef50_C6CA70 CRISPR-associated protein Cas1 n=56 Tax=Bacteria RepID=C6CA70_DICDC
          Length = 333

 Score =  231 bits (588), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 69/311 (22%), Positives = 126/311 (40%), Gaps = 46/311 (14%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRT---HIPVGSVACIMLEPGTRVS 61
            L  I    R ++ +LQ+ +I V  G    + + G ++   +IP+ + + +ML  GT V+
Sbjct: 9   DLKTILHSKRANIYYLQHCRILVNGGRVEYVTEEGNQSLYWNIPIANTSVVMLGTGTSVT 68

Query: 62  HAAVRLAAQVGTLLVWVGEAGVRVYAS-----------GQPGGARSDKLLYQAKLALDED 110
            AA+R  A+ G ++ + G  G  ++A+            Q     ++ L        +E 
Sbjct: 69  QAAMREFARAGVMVGFCGSGGTPLFAANEAEVAVSWLSPQSEYRPTEYLQDWVSFWFNEQ 128

Query: 111 LRLKVVRKMFELRFGE----------PAPARRSV-----EQL-----RGIEGSR----VR 146
            RL       ++R G+             +R ++     E L     +G+   R    V 
Sbjct: 129 QRLAAAIAFQQVRIGQIRQHWLGGRLARESRFTIKPEHVEALLNRYQQGLVDCRTSNDVL 188

Query: 147 ATYALLAKQ-YGVTWNGRRY----DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYA 201
              A++ K  Y +  N   Y      K     D  N+ +       YG+   A+   G  
Sbjct: 189 VQEAMMTKALYRLAANAVSYGDFTRAKRGGGTDLANRFLDHGNYLAYGLAAVALWVLGLP 248

Query: 202 PAIGFVHTGKPL-SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKT 260
             +  +H        V+D+AD+IK   ++P+AF  A    GE +++ R  C   FR ++ 
Sbjct: 249 HGLAVLHGKTRRGGLVFDVADLIKDALILPQAFIAAME--GEDEQDFRQRCLTAFRQAEA 306

Query: 261 LAKLIPLIEDV 271
           L  +I  ++ V
Sbjct: 307 LDVMIDSLQQV 317


>UniRef50_B7GYY4 CRISPR-associated protein Cas1 n=8 Tax=Proteobacteria
           RepID=B7GYY4_ACIB3
          Length = 321

 Score =  213 bits (543), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 57/308 (18%), Positives = 112/308 (36%), Gaps = 51/308 (16%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIR---THIPVGSVACIMLEPGTRVS 61
            L  I    R ++ +L++ ++   DG  + + +        +IP+ +   I+L  GT ++
Sbjct: 8   DLKAILHSKRANLYYLEHCRVMQKDGRVLYLTEAKNENQYWNIPIANTTVILLGTGTSIT 67

Query: 62  HAAVRLAAQVGTLLVWVGEAGVRVYAS-------GQPGGARSDKLLYQAKLALDEDLRLK 114
            AA+R+    G L+ + G  G  ++A         Q     ++ +        DE  RL 
Sbjct: 68  QAAMRMLCSAGVLVGFCGGGGTPLFAGSEVEWLTPQSEYRPTEYMQGWMSFWFDETKRLD 127

Query: 115 VVRKMFELR--------------------------------FGEPAPARRSVEQLRGIEG 142
           V +     R                                F +  P    V  L   E 
Sbjct: 128 VAKAFQFARIEFIRKIWAKDKDLKDEGFYLDNLDIQQALNGFEKKIPNMTKVGDLLLAEA 187

Query: 143 SRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAP 202
              +  Y + A +  +++        + E+GD  N  ++      YG++   +   G + 
Sbjct: 188 QTTKQLYKIAATRCKLSFER------NPEQGDLANDFLNHGNYLAYGLSATTLWVLGISH 241

Query: 203 AIGFVHTGKPL-SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTL 261
           +   +H      + V+D+AD+IK   V+P AF  A+      ++E R      F   + L
Sbjct: 242 SFAVMHGKTRRGALVFDVADLIKDAVVLPWAFICAKEGAT--EQEFRQQLLQKFTDYRCL 299

Query: 262 AKLIPLIE 269
             +   ++
Sbjct: 300 DWMFDQVK 307


>UniRef50_A9BUF1 CRISPR-associated protein Cas1 n=33 Tax=Proteobacteria
           RepID=A9BUF1_DELAS
          Length = 337

 Score =  199 bits (506), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 66/334 (19%), Positives = 122/334 (36%), Gaps = 56/334 (16%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRT---HIPVGSVACIMLEPGTRVS 61
            L  I    R ++ +L++ ++ V  G    +   G R+   +IP+ +   I+L  GT ++
Sbjct: 8   DLKTILHSKRANIYYLEHCRVLVNGGRVEYVTDAGKRSLYWNIPIANTTSILLGAGTSIT 67

Query: 62  HAAVRLAAQVGTLLVWVGEAGVRVYAS-----------GQPGGARSDKLLYQAKLALDED 110
            AA+R  A+ G L+ + G  G  ++++            Q     ++ L    +   D++
Sbjct: 68  QAAMRELAKAGVLVGFCGGGGTPLFSANEVDVEVAWLTPQSEYRPTEYLQAWVQFWFDDE 127

Query: 111 LRLKVVRKMFELR-------------------------------FGEPAPARRSVEQLRG 139
           LRL   +++  LR                               F         V  L  
Sbjct: 128 LRLHAAKQLQALRLQRLQQEWGARALRESGFAVDMERLKALVQQFAALMANAPDVMTLLT 187

Query: 140 IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAG 199
            E    +A + L     G    G     K     D  N+ +       YG+   A    G
Sbjct: 188 DEARLTKALFKLAVDAVGY---GEFTRAKRGTGTDGANRYLDHGNYLAYGLGATATWVLG 244

Query: 200 YAPAIGFVHTGKPL-SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSS 258
               +  +H        V+D AD++K   ++P+AF  A R  G+ + + R  C +    S
Sbjct: 245 LPHGLAVLHGKTRRGGLVFDAADLVKDAAILPQAFLSAMR--GDDEPQFRRQCIEALTRS 302

Query: 259 KTLAKLIPLIEDVL-----AAGEIQPPAPPEDAQ 287
           ++L  +I  ++ +       AG    P   ++A 
Sbjct: 303 ESLDFIIDTLKRIAVDTARMAGASATPGAAQEAG 336


>UniRef50_D1BQ37 CRISPR-associated protein Cas1 n=1 Tax=Veillonella parvula DSM 2008
           RepID=D1BQ37_VEIPT
          Length = 331

 Score =  145 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 60/284 (21%), Positives = 109/284 (38%), Gaps = 39/284 (13%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           I    G  VL     +   IP+ +V+ ++L    ++S   +    + G+L+ +V +   +
Sbjct: 14  IRQDGGLLVLEKDHSVIKEIPIATVSNLVLGRTIQISTQVMFSLVKQGSLIQFV-DHKYQ 72

Query: 85  VYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA---------------- 128
           +  +         +LL+Q     +++  L   + +   +                     
Sbjct: 73  LVGTLGDEHTPLQRLLWQVACFQNQEFALDGAKYIVRRKIKGQIALLNQYKKSKCIPNFV 132

Query: 129 -------------PARRSVEQLRGIEGSRVRATYALLAKQYGVTW--NGRRYDPKDWEKG 173
                           + VE LRGIEG   R  +++L       W  +GR+  P      
Sbjct: 133 VVHRTMQALLKRVERTKKVETLRGIEGLASRTYFSVLGHVLSEPWEFSGRKRHP----SP 188

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPK 231
           D +N  +S   S L     A +L AG    IG +H+   +  S VYD+ DI + D +   
Sbjct: 189 DPVNAILSYGYSFLEREVRACLLTAGLDVRIGVLHSTNNRKDSLVYDVMDIFRQDIIDRF 248

Query: 232 AFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
             ++  R+   P+ +  L+ R  F S +   K + L ED + A 
Sbjct: 249 VLKLLNRHMILPE-DFDLSERGCFLSKEANKKWVELYEDYMKAE 291


>UniRef50_D2QT50 CRISPR-associated protein Cas1 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QT50_9SPHI
          Length = 351

 Score =  116 bits (291), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 56/252 (22%), Positives = 90/252 (35%), Gaps = 59/252 (23%)

Query: 46  VGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLL----- 100
              V  I+L  GT +S  AVRLA +    +V++ + G  +          + K+      
Sbjct: 37  AEKVTHILLATGTSLSTDAVRLAMRHNVDIVFIEQQGDPIGRVWHAKLGSTTKIRKRQLE 96

Query: 101 --------YQAKLA--LDEDLRLKVVRKMFELR--------------------------F 124
                      +       D ++  +R + + R                           
Sbjct: 97  ASLGPDGLRWVRAWLLAKLDNQMGFIRSLKKHRPQHAGYLDDKLVRIEAMALSISTLASV 156

Query: 125 GEPAPARRSV----EQLRGIEGSRVRATYALLA----KQYGVTWNGRRYDPKDWEKGDTI 176
           GE  PA   V    + LRG+EG+  R  +  L+    K+Y   ++GR   P      D  
Sbjct: 157 GEQTPATTCVADVADTLRGLEGTAGRLYFETLSYVLPKEY--QFSGRSSRPAQ----DAF 210

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK--FDTVVPKA 232
           N  ++     LYG  E  ++ AG  P +GF+H      LS VYD  +  +   D VV + 
Sbjct: 211 NAFLNYGYGMLYGKVEKTLMMAGLDPYVGFLHRDDYNQLSMVYDFIEPYRGWTDEVVFRL 270

Query: 233 FEIARRNPGEPD 244
           F   + N     
Sbjct: 271 FTAKKVNKAHIG 282


>UniRef50_A3LCN8 Putative uncharacterized protein n=1 Tax=Pseudomonas aeruginosa
          2192 RepID=A3LCN8_PSEAE
          Length = 112

 Score =  110 bits (275), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 64/78 (82%), Positives = 73/78 (93%)

Query: 5  PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
          PL P+P+KDR+SM+F+QYGQIDV DGAFV+ID+TG+R HIPVGSVACIMLEPGTRVSHAA
Sbjct: 4  PLKPLPMKDRLSMVFVQYGQIDVRDGAFVVIDQTGVRMHIPVGSVACIMLEPGTRVSHAA 63

Query: 65 VRLAAQVGTLLVWVGEAG 82
          V LA+ VGTLLVWVGEAG
Sbjct: 64 VHLASTVGTLLVWVGEAG 81


>UniRef50_C8W2P4 CRISPR-associated protein Cas1 n=1 Tax=Desulfotomaculum acetoxidans
           DSM 771 RepID=C8W2P4_DESAS
          Length = 545

 Score = 98.5 bits (244), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 51/289 (17%), Positives = 100/289 (34%), Gaps = 40/289 (13%)

Query: 5   PLNPIPLKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           P  P+P  +   ++++      +        +     +   IP+ ++  ++L     +S 
Sbjct: 203 PARPLPSLNLGRVLYVDEPGAYVRKKGERVQVTRDKEVLVDIPLCNLEQLVLAGTVNISA 262

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE- 121
             ++L    GT + +V  AG    +        S   + Q K   D +LRLK      + 
Sbjct: 263 QVIKLLLDRGTEVHFVSRAGKYYGSLQPALTKNSALRIAQHKAYQDMELRLKYAVLFVQG 322

Query: 122 ---------LRFGEPAPARR-------------------SVEQLRGIEGSRVRATYALLA 153
                    LR+      ++                   S+  L GIEG+  R  + +  
Sbjct: 323 KLANMRTILLRYNRDLKEKQLEEAICRLKSLSKNLYKADSLNSLMGIEGAATREYFRVFN 382

Query: 154 K--QYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT-- 209
              +  V +N ++   +    GD +N  +S A + L     A++   GY P IGF+H   
Sbjct: 383 YMIKQHVPFNFQQRSRRPP--GDPVNALLSFAYTLLTKDMIASVSIVGYDPYIGFLHRSD 440

Query: 210 -GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRS 257
            G+P +   D  +  +          +  +     D +        F +
Sbjct: 441 YGRP-ALALDFIEEFRPIVADSVVLTVLNKGMINTD-DFEYKMGGCFLN 487


>UniRef50_B9LWK7 CRISPR-associated protein Cas1 n=4 Tax=Halobacteriaceae
           RepID=B9LWK7_HALLT
          Length = 331

 Score = 95.1 bits (235), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 50/256 (19%), Positives = 82/256 (32%), Gaps = 40/256 (15%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           G++   +    +    G   H+PV S+  + L      +  A+ L    G      G   
Sbjct: 12  GELSRSEDTLRIDTLDGEVEHLPVESIDTLYLHGQIDFNTRALGLLNDHGVPAHVFGWKD 71

Query: 83  VRVYASGQPGGAR---SDKLLYQAKLALDEDLRLKVVRKM--------------FELR-- 123
              Y             + ++ Q +   D D RL +   M              +  R  
Sbjct: 72  --YYKGSYLPKRSHLSGNTVVEQVRAYDDPDRRLGIATLMIEASIHNMRANLVYYNARDC 129

Query: 124 -FGEPAPA----------RRSVEQLRGIEGSRVRATYALLAKQYGVTW--NGRRYDPKDW 170
            F                  S++ LRG E +  +  Y+  ++     +  + R Y+P   
Sbjct: 130 SFDSEIDRLESLKTKASTAESIDGLRGTEATARKTYYSCFSEILRDPFALDRREYNPP-- 187

Query: 171 EKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFV--YDIADIIKFDTV 228
              +  N  IS   + +Y    +AI      P +GF+H      F    DIADI K    
Sbjct: 188 --TNETNALISFLNAMVYTACVSAIRKTALDPTVGFMHEPGDRRFTLSLDIADIYKPILA 245

Query: 229 VPKAFEIARRNPGEPD 244
               F +  R    PD
Sbjct: 246 DRVLFRLVNRRQISPD 261


>UniRef50_A4X3M4 CRISPR-associated protein, Cas1 family n=4 Tax=Actinomycetales
           RepID=A4X3M4_SALTO
          Length = 326

 Score = 93.5 bits (231), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 52/266 (19%), Positives = 86/266 (32%), Gaps = 38/266 (14%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           S    +  +I   D +  +    G    IP+  +  ++L     ++ AAV L ++ G  +
Sbjct: 7   SYWLTEPCRIRREDNSIRIERADGQPVRIPITDIRDLVLFDNADINTAAVSLLSRHGVTV 66

Query: 76  VWVGEAGVRVYASGQPGG---ARSDKLLYQAKLALDEDLRLKVVRKMFEL---------- 122
             +   G   YA         + +  +  Q  L  +   RL V + +             
Sbjct: 67  HLLDHYG--NYAGALTPADDMSSAHVVRAQVALTGNPQARLAVAQALVRATAVNVAWALG 124

Query: 123 ---------RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW---NGRRYDPKDW 170
                    R      A  S   L G+EG+  R  + +L       W   +GR   P   
Sbjct: 125 TDLLDGPLERLPAQIGASTSSGDLMGVEGNFRRTAWGVL-DTLLPPWLRLDGRTRRPP-- 181

Query: 171 EKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL---SFVYDIADIIKFDT 227
              +  N  IS   +  Y     AI      PAIGF+H        +   D+A+  K   
Sbjct: 182 --SNAGNAFISYLNAITYARVLTAIRCTPLHPAIGFLHADTDRRRNTLALDLAEPFKPLL 239

Query: 228 VVPKAFEIARRN---PGEPDREVRLA 250
                   A +      +   +VR A
Sbjct: 240 AERLLRRAAAQRTLTAADFVSDVRSA 265


>UniRef50_O57912 Putative uncharacterized protein PH0173 n=1 Tax=Pyrococcus
           horikoshii RepID=O57912_PYRHO
          Length = 317

 Score = 91.6 bits (226), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 49/257 (19%), Positives = 94/257 (36%), Gaps = 31/257 (12%)

Query: 16  SMIFL-QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
           S I++ Q G ++        +++  ++  +P+ +++ I       ++  A++L +     
Sbjct: 3   SPIYITQPGILERKANTLFFVNEE-MKRALPINTISEIHCFAPVTLTSGAIKLLSDNDVP 61

Query: 75  LVWVGEAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVRKMFE---------- 121
           + +  + G   Y               ++ QA   +D + RL + R++ E          
Sbjct: 62  VHFYNKYG--YYRGSYLPAESQISGSIVVAQASHYIDNEKRLYIAREILEGTRASMISLL 119

Query: 122 -------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG-VTWNGRRYDPKDWEKG 173
                      +      S+E+L GIE    +  YA  +       ++ R   P      
Sbjct: 120 KSQRAEYKDLADIDLKGESIEELMGIESQLWKTFYAHFSHLLKFFNFDERNRRPPR---- 175

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPK 231
           D IN  IS   S LY VT + I      P I ++H  +    S   D+A+I K   V   
Sbjct: 176 DEINAMISYGNSVLYTVTLSEIRKTYLHPGISYLHEPRERRYSLALDLAEIFKPIVVFRV 235

Query: 232 AFEIARRNPGEPDREVR 248
              +  +     +  VR
Sbjct: 236 ILRLVNKRIIREEHFVR 252


>UniRef50_A1ZHZ5 Crispr-associated protein Cas1 n=1 Tax=Microscilla marina ATCC
           23134 RepID=A1ZHZ5_9SPHI
          Length = 344

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 14/127 (11%)

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALL----AKQYGVTWNGRRYDPKDWEKGDTINQCIS 181
           E        + LRG+EG+  R  +  L    AK+Y   + GR   P      D  N  ++
Sbjct: 159 EADHTEAIADTLRGLEGTAGRLYFETLSYVLAKEY--QFAGRSKRPAH----DAFNAFLN 212

Query: 182 AATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK--FDTVVPKAFEIAR 237
                LY + E A++ AG  P +GF+H       S VYD  +  +   + VV K F   +
Sbjct: 213 YGYGILYSMVEHALVIAGIDPFVGFMHRDGYNQRSMVYDFIEPYRGHVEQVVVKLFTAKK 272

Query: 238 RNPGEPD 244
            N    D
Sbjct: 273 VNQSHTD 279


>UniRef50_A9AYP8 CRISPR-associated protein Cas1 n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9AYP8_HERA2
          Length = 333

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 58/295 (19%), Positives = 106/295 (35%), Gaps = 43/295 (14%)

Query: 18  IFL-QYG-QIDVIDGAFVLIDKTGIRTHIPVGSVA-CIMLEPGTRVSHAAVRLAAQVGTL 74
           ++L + G ++   D   +++    +   IPV  V   I++  G +VSHAA+   AQ G  
Sbjct: 4   LYLNEQGTRLGKKDERLIILRGQELINDIPVIKVDRVIVMGQGVQVSHAAIVFLAQRGIP 63

Query: 75  LVWVG-EAGVRVYASGQPGGARSDKLLYQAKLALDEDLRL---------KVVRKMFEL-R 123
           L++     G +        G  +   L Q ++  +  L +         KV  ++  L R
Sbjct: 64  LIFTTQSGGSQKAMVSAGLGNNAALRLAQCRIVDNPHLAVPLVQAIVVGKVANQIQLLER 123

Query: 124 FG------------------EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW--NGR 163
           +G                  +       +EQLRG+EG+   A +   +  +   W   GR
Sbjct: 124 YGSDWGGMGLRAKQTMQHVIQQTQHMPDIEQLRGLEGAGAAAYWGTWSAVFKTAWGFAGR 183

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIA 220
            Y P      D +N  +S   + L      A+ A  + P +G  HT   G+P S   D+ 
Sbjct: 184 AYRPT----PDPLNALLSFGYTLLLNDLMTAVQALSFDPYLGVFHTVQFGRP-SLALDLE 238

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
           +  +   V     ++      +         +    + +     I   E  +   
Sbjct: 239 EEFRPCIVDRMVLDVLDAGLLQM-SNFSRTEKGFLLNDRARKSFIQAYEQRMQTP 292


>UniRef50_B8CYA1 CRISPR-associated protein Cas1 n=2 Tax=cellular organisms
           RepID=B8CYA1_HALOH
          Length = 325

 Score = 88.9 bits (219), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 56/266 (21%), Positives = 97/266 (36%), Gaps = 52/266 (19%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           + V   +F +  +   +  +    V+ I++  G  +S  AV+LA +    + ++ E G  
Sbjct: 12  LHVKQKSFEIKTEEDKK-RVSAKKVSSILITTGAAISTDAVKLALENNIEIQFLDEFGCS 70

Query: 85  VYASGQPGGARSDKLLY-QAKLALDED-------------------------LRLKVVRK 118
           +     P    +  +   Q +LA  E+                          R K   K
Sbjct: 71  LGKVWHPKLGSTTYIRRKQLELAESEEGTELVKEFMLDKIDNMINHLHDLAIKRSKSKEK 130

Query: 119 MFELRFGEPAPARRSVE-----------QLRGIEGSRVRATYALLA----KQYGVTWNGR 163
               +  E    R  +E            + G EG+  R  +A L+     +Y   +NGR
Sbjct: 131 YINKKIKEICELRNKLEKVTGYIEDVRNTIMGYEGNISRKYFASLSFLLPDRY--KFNGR 188

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIAD 221
            + P +    D  N  ++     LYG  E A++ AG  P +G +HT      SFV+D  +
Sbjct: 189 SFRPAE----DEFNCLLNYGYGVLYGKVEKALIIAGLDPYVGILHTDGYNKKSFVFDFIE 244

Query: 222 IIKFDT--VVPKAFEIARRNPGEPDR 245
             +     VV K F   +      D+
Sbjct: 245 PYRHHIDRVVMKLFSRKKIRKLHFDK 270


>UniRef50_Q2FL78 CRISPR-associated protein, Cas1 family n=1 Tax=Methanospirillum
           hungatei JF-1 RepID=Q2FL78_METHJ
          Length = 331

 Score = 88.9 bits (219), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 53/261 (20%), Positives = 93/261 (35%), Gaps = 42/261 (16%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVA-----CIMLEPGTRVSHAAVRLAAQVGTLLVWV 78
           +I        +       T  P  +++      + +     +S AAVRL    G  +  +
Sbjct: 12  RIRKRGDVLTIETGKDSDTAEPPRTLSPLGLDLLAIAGDHSISTAAVRLVTSHGGAIALM 71

Query: 79  GEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM------------------- 119
              G   +    P G  +    Y+A+ +  E+ RL++ R +                   
Sbjct: 72  DGLGNP-FGHFLPLGRSALIEQYEAQASAPEERRLEIARSICTGALENKRTLLSNLERIR 130

Query: 120 -----FELRFGEPAPARR----SVEQLRGIEGSRVRATYALLAKQYGVTWN--GRRYDPK 168
                 E+R  E A  +     S++ LRG+EGS   A +   +  +   W   GR  +P 
Sbjct: 131 GFDLSREIRLVEDAQDKALECQSLDSLRGVEGSGAHAYFQGFSLAFDEEWGFLGRSQNPA 190

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFD 226
                D +N  +S     LY     A++ +GY+P  G  H    K  + VYD+ +  +  
Sbjct: 191 ----TDPVNSLLSYGYGMLYIQARQALVLSGYSPYYGAYHETYKKQEALVYDLVEEFRQP 246

Query: 227 TVVPKAFEIARRNPGEPDREV 247
            V         ++   PD   
Sbjct: 247 VVDRTVVTFLAKHMATPDDFT 267


>UniRef50_D2NTT1 Uncharacterized protein predicted to be involved in DNA repair n=2
           Tax=Rothia mucilaginosa RepID=D2NTT1_9MICC
          Length = 560

 Score = 88.1 bits (217), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 44/248 (17%), Positives = 75/248 (30%), Gaps = 39/248 (15%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV 83
           +  V  G  ++       + +P+  V  +++     VS A +R        ++W    G 
Sbjct: 243 RATVQQGRLIVQHLGETISSVPLERVHSLVVHGNIDVSSALLRELMWRNCTIIWCSSTG- 301

Query: 84  RVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP---------------- 127
           RVY   QPG   +     Q  +       L +   M   +                    
Sbjct: 302 RVYGWSQPGTGPNGLARVQQHVLS-AQGYLPIASAMIASKIANQATLLRRNGHAADVCRT 360

Query: 128 -------APARRSVEQLRGIEGSRVRATYALLAK--------QYGVTWNGRRYDPKDWEK 172
                   P   S+ +L G+EG      +   A         + G  W GR+        
Sbjct: 361 MRDIQKNTPQATSIPELLGLEGEAASLYFGNFATMLKEDALTELGWIWTGRQGR----GA 416

Query: 173 GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVP 230
            D IN  ++ A   L       IL  G  P  GF+H+      +   D+ +  +      
Sbjct: 417 NDPINILLNYAYGMLSSECIRGILTCGLDPHAGFLHSSSRNKPALALDLMEEFRAVIADS 476

Query: 231 KAFEIARR 238
               +  R
Sbjct: 477 VVVSLINR 484


>UniRef50_B0VIK5 Putative uncharacterized protein n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VIK5_9BACT
          Length = 353

 Score = 87.4 bits (215), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 43/262 (16%), Positives = 83/262 (31%), Gaps = 45/262 (17%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
           YG           +     +T +    ++ I++     ++  A++LA      +V++ + 
Sbjct: 9   YGSYLRKKDEMFELSIEDRKTKLSPEKISSIVISNAATITTDAIQLAMDYNIDIVFLDKY 68

Query: 82  GVRVYASGQPGGARSDKLLY-------------------------QAKLALDEDLRLKVV 116
           G        P    +  +                           Q +       +    
Sbjct: 69  GSPYGRIWFPKIGSTVLIRRRQLEMLSDNVGLQFIKDWIAIKIMNQYRFVQRLISKRDCD 128

Query: 117 RKMFELRFGEPAPARRSVEQ-----------LRGIEGSRVRATYALLAKQY--GVTWNGR 163
           + +F+ R      A   + Q             G EG   +  +++LA+       + GR
Sbjct: 129 KSIFQTRMQNMQEAAICIMQAEGKLEELSGSFMGWEGGASKNYFSILAELIPDAYKFEGR 188

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIAD 221
              P      D  N  ++     LY   E A++ AG  P +G +H+      SFV+D  +
Sbjct: 189 SSRPAK----DAFNAMLNYGYGILYSKVERALIIAGLDPYLGLLHSDNYNKKSFVFDFIE 244

Query: 222 IIKFDTVVPKAFEIARRNPGEP 243
             +     P  F I  R+   P
Sbjct: 245 PYRILVDEPV-FYIFSRHKFSP 265


>UniRef50_Q1CWU5 CRISPR-associated protein Cas1 n=1 Tax=Myxococcus xanthus DK 1622
           RepID=Q1CWU5_MYXXD
          Length = 342

 Score = 86.2 bits (212), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 47/275 (17%), Positives = 89/275 (32%), Gaps = 38/275 (13%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            I  +  +++      V+  +   +  +P+  +  ++      ++   +    + G  + 
Sbjct: 9   FITAEGTRLNKEGECVVVTVQDQKKAEVPLRHLRSVVCLTRAWLTPELMESCLEAGIHVS 68

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLR------------LKVVRKMF---- 120
           + G  G R  A  +     +  L  Q   A D+  R            L   R+      
Sbjct: 69  FFGMTG-RFLARVEGVPGGNVLLRRQQYRAADDIARSVAISRALVVGKLGNARQFVLHAR 127

Query: 121 --------------ELRFGEPAPARRSVEQL---RGIEGSRVRATYALLAKQYGVTWNGR 163
                           R  E   A   VE L   RG+EG   R  +         +  G 
Sbjct: 128 RDAAPERQEALSETARRLSEHLRALTRVEDLVQVRGLEGIAARDYFESFPALLKKSAQGF 187

Query: 164 RYDPKDWEKG-DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKP--LSFVYDIA 220
            +D ++     + +N  +S   + L      A+   G  PA+GF+H  +P  LS   D+ 
Sbjct: 188 EFDGRNRRPPRNPLNAMLSFGYALLAQDCAGALTGVGLDPAVGFLHEDRPGRLSLALDLM 247

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIF 255
           +  +   V    F +  R   +P  + R       
Sbjct: 248 EEFRAPVVDRLVFSLVNRGQLKPG-DFRTESAGAV 281


>UniRef50_Q96X75 Putative uncharacterized protein ST2634 n=1 Tax=Sulfolobus tokodaii
           RepID=Q96X75_SULTO
          Length = 317

 Score = 86.2 bits (212), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 53/254 (20%), Positives = 96/254 (37%), Gaps = 29/254 (11%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVA-CIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           ++      FV+  K G + ++    V   +++  G  V+  A+RLA   G  ++++   G
Sbjct: 25  KLSTKGKTFVISKKDGKKVNVSPAEVDQIVIMTSGVTVTSKAIRLALDHGIDIIFLDSRG 84

Query: 83  V---RVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR----------KMFELRFGEPAP 129
               R++ S       + K  Y A L  +E++  ++++          K +  + G    
Sbjct: 85  NPFGRLFHSEPIKTVETRKAQYLAILKGEEEIPREIIKSKIKNQANHIKFWFKKLGIEGN 144

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
             + +E     E +  R  +  L +   +   GR     D E  D  N   + A + LY 
Sbjct: 145 DYKLIEGKDDDEATAARYYWHALGRI--IPMKGR-----DPESTDPFNVSFNYAYAILYS 197

Query: 190 VTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVV-PKA--FE---IARRNPG 241
             +  +   G  P  GF+H  +    S VYD +++ K   V  P    F    I     G
Sbjct: 198 NIQRVLQLVGLDPYAGFIHKDRSGKPSLVYDFSEMFKPVLVDYPLVSLFINGFIPNVKDG 257

Query: 242 EPDREVRLACRDIF 255
             D E R    +  
Sbjct: 258 ILDAESRKKIAEAV 271


>UniRef50_A3XI90 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XI90_9FLAO
          Length = 332

 Score = 85.8 bits (211), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 55/247 (22%), Positives = 82/247 (33%), Gaps = 51/247 (20%)

Query: 43  HIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRV--YASGQPGGAR----- 95
           HI    V   ++  G  ++  A+ LA +    +V V   G  +  +   + G        
Sbjct: 35  HIAAHKVTSFIVSKGAALTTDAIALALKHNIDIVLVENNGHPMGRFWHSKLGSTTKIRKQ 94

Query: 96  ------------------SDKLLYQAKLALDEDLRLK----------VVRKMFELRFGEP 127
                             S KL  QA    D     K               F  +  E 
Sbjct: 95  QLVASLNQTGVYWIKEWLSQKLENQADYLNDLKKHRKNLHVYLDEKSAAILGFRKKIKEA 154

Query: 128 APARRSV--EQLRGIEGSRVRATYALLA----KQYGVTWNGRRYDPKDWEKGDTINQCIS 181
             A  +   E  RG EGS  R  +  LA      Y   + GR + P      D  N  ++
Sbjct: 155 DGADINQLAESFRGWEGSAGRHYFEALATCIPDAYS--FKGRSFRPAQ----DEFNALLN 208

Query: 182 AATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK--FDTVVPKAFEIAR 237
            A   LY   E A++ AG  P +GF+H       S VYD  +  +   +  V K+F   +
Sbjct: 209 YAYGILYSRVERALMLAGLDPFVGFMHRDDYNSKSLVYDFIEPYRIYAERFVFKSFSSKK 268

Query: 238 RNPGEPD 244
            N    +
Sbjct: 269 MNKSYFE 275


>UniRef50_C7QUZ4 CRISPR-associated protein Cas1 n=8 Tax=Cyanobacteria
           RepID=C7QUZ4_CYAP0
          Length = 325

 Score = 85.4 bits (210), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 47/259 (18%), Positives = 95/259 (36%), Gaps = 34/259 (13%)

Query: 15  VSMIFLQY--GQIDVIDGAFVL----IDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +S+++L      +     AF +     D +  +  IP  +V  I+L     ++  A+  A
Sbjct: 1   MSILYLTQPDAVLSKKQEAFHVALKQEDGSWKKQLIPAQTVEQIVLIGYPSITGEALCYA 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR----------- 117
            ++G  + ++   G  + ++           L Q  +  +E+ RL +V+           
Sbjct: 61  LELGIPVHYLSCFGKYLGSALPGYSRNGQLRLAQYHVHDNEEQRLALVKTVVTGKIHNQY 120

Query: 118 ----KMFELRFG-----EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWN--GRRYD 166
               +  +         +   ++ ++EQ+RG+EG   +  +          WN  GR   
Sbjct: 121 HVLYRYQQKDNPLKEHKQLVKSKTTLEQVRGVEGLAAKDYFNGFKLILDSQWNFNGRNRR 180

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIK 224
           P      D +N  +S A   L     AA+  AG  P IG++H       + V D+ +  +
Sbjct: 181 PP----TDPVNALLSFAYGLLRVQVTAAVHIAGLDPYIGYLHETTRGQPAMVLDLMEEFR 236

Query: 225 FDTVVPKAFEIARRNPGEP 243
                     +      +P
Sbjct: 237 PLIADSLVLSVISHKEIKP 255


>UniRef50_C1ZJF3 CRISPR-associated protein, Cas1 family; CRISPR-associated
           exonuclease, Cas4 family n=1 Tax=Planctomyces
           limnophilus DSM 3776 RepID=C1ZJF3_PLALI
          Length = 598

 Score = 85.1 bits (209), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 54/288 (18%), Positives = 92/288 (31%), Gaps = 39/288 (13%)

Query: 6   LNPIPLKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
              +P +D    I++Q     I        L         IP+  V+ + L    +V+ A
Sbjct: 261 RKLVPARDDALPIYVQDQGTYIGKDGERLKLTPAKSSPLFIPLIQVSQVCLMGNVQVTAA 320

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE-- 121
           A+R  A     + +    G     +        +  + Q+K A D    L + R      
Sbjct: 321 AIRELADRNIPISYFSYGGWFTALTSGMCHKNVELRMAQSKAAFDPQAALSIARGFISAK 380

Query: 122 -------LRFGEPAPARR----------------SVEQLRGIEGSRVRATYALLAK--QY 156
                  LR       R                 ++  L G+EG   +  +A  ++  + 
Sbjct: 381 IKNSRTLLRRHADDKHRSDLDRLADYIQKVEQVDNLNSLMGLEGMAAKTYFAGFSRLLRG 440

Query: 157 GVTWN--GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GK 211
           G  +N  GR   P      D +N  +S   S L         A G+ P +GF+H    G+
Sbjct: 441 GDEFNLEGRNRRPP----TDPVNALLSFVYSLLTKELTITTQAVGFDPFLGFLHQPRYGR 496

Query: 212 PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSK 259
           P S   D+A+  +          +       P   +R A       + 
Sbjct: 497 P-SLALDLAEEFRPLVGDSTVLTLINNEEVSPKSFIRRAGSVALTETG 543


>UniRef50_C7NA04 CRISPR-associated protein Cas1 n=1 Tax=Leptotrichia buccalis
           C-1013-b RepID=C7NA04_LEPBD
          Length = 323

 Score = 83.9 bits (206), Expect = 6e-15,   Method: Composition-based stats.
 Identities = 39/264 (14%), Positives = 85/264 (32%), Gaps = 49/264 (18%)

Query: 18  IFL-QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
           +++   G +         I  +  +  +    +  ++L  G  ++   ++LA      +V
Sbjct: 3   LYITDLGTVVKKRDDLFEITTSEKKVAVAPQKIKSLVLSKGIFLTTDVIKLAVDNNIDIV 62

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM----------------- 119
            V + G       Q     +  +  +          +++ +++                 
Sbjct: 63  IVDDFGNPYGRFWQSKFGSTANIRRKQLEIFGTQKGIELAKQILIQKIKNCAEHLEDLKI 122

Query: 120 --------------------FELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--G 157
                               ++++  E   + +    L G EG+  +  Y  L++    G
Sbjct: 123 KREAKKAFLDKQIKEMKRYIYQIKLVEGNVSEK-RGTLMGYEGNAAKIYYQTLSELIPEG 181

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSF 215
             +  R   P +    D  N  ++ A   LY   E A + AG  P +G +HT      S 
Sbjct: 182 FKFEKRSMHPAE----DEFNAMLNYAFGILYSKVEKACIIAGLDPYVGIIHTDNYGKKSL 237

Query: 216 VYDIADIIK--FDTVVPKAFEIAR 237
           V+D+ +  +      V   F   R
Sbjct: 238 VFDLIESYRHLASRTVFSLFTQKR 261


>UniRef50_UPI0001C16754 protein of unknown function DUF48 n=1 Tax=Cylindrospermopsis
           raciborskii CS-505 RepID=UPI0001C16754
          Length = 334

 Score = 83.5 bits (205), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 47/280 (16%), Positives = 96/280 (34%), Gaps = 37/280 (13%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           +  ID    +       T +P+  +  +++     ++  A+++  Q    + ++ E G R
Sbjct: 13  VRQIDERLEIFKHDKRLTDVPLCKLESVVVYGRVILTIPALKILNQRSIPITYLSEEG-R 71

Query: 85  VYASGQPGGARSDKLL-YQAKLALDEDLRLKVVRKMFE----------LRFGEPAPA--- 130
             A+  P    +  L   Q + + D    L + R++             RF         
Sbjct: 72  TVATLLPEPNPNAILRSKQYQASFDTHKTLAIAREIIRGKLFNQHTILARFSRQNERSEK 131

Query: 131 -----------------RRSVEQLRGIEGSRVRATYALLAKQ-YGVTWNGRRYDPKDWEK 172
                              S+ +LRG EG    + + +L +   G  W+      +    
Sbjct: 132 VISALKSLKACQKSIDQTTSLNELRGYEGQGASSYFGVLGELLTGTPWSFSHRTRRPP-- 189

Query: 173 GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFDTVVP 230
            D +N  +    + LYG   AA+   G  P  GF+H  +    +   D+ +  +   V  
Sbjct: 190 TDPVNALLGFGYALLYGDCRAALHTVGLDPYQGFLHGERYGRANLALDLMEEFRPIFVDG 249

Query: 231 KAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
              ++ R N  E +  +      +  + + + K I   E 
Sbjct: 250 LVLQLLRNNSLEKESFINYPGGAVHLNEQGMKKFIQSYEQ 289


>UniRef50_C0QHV1 Putative CRISPR-associated protein (Uncharacterized protein,
           predicted to be involved in DNA repair) n=1
           Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QHV1_DESAH
          Length = 338

 Score = 83.5 bits (205), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 8/95 (8%)

Query: 134 VEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
              + G+EG+  RA + +LA+       + GR   P      D  N  ++     LYG  
Sbjct: 157 RNTIMGLEGTSARAYFKVLARAMPEKYRFKGRSRRPAK----DPFNAVLNYCYGMLYGKV 212

Query: 192 EAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK 224
           E A + AG  P IGF+HT      S V+D+ +  +
Sbjct: 213 EKACIIAGLDPFIGFLHTDNYNKKSLVFDLIEPFR 247


>UniRef50_B7KMR5 CRISPR-associated protein Cas1 n=3 Tax=Chroococcales
           RepID=B7KMR5_CYAP7
          Length = 558

 Score = 82.4 bits (202), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 62/310 (20%), Positives = 107/310 (34%), Gaps = 48/310 (15%)

Query: 3   WLPLNPIPLKDRVSMIF-LQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60
           W P+   P+ D   +I  L+ G ++        +         I +G V+ ++L   +++
Sbjct: 210 WHPVRLFPVDDEREVIHVLEPGTRVGRTGEQLKISRPNQPDEKIAIGQVSQVVLHSFSQI 269

Query: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120
           S  AV   A     + +V   G R   S         + + Q +     D  L++ RK+ 
Sbjct: 270 STQAVHFLAYKEVGIHFVSGGG-RYIGSIDARSRSIQRRVRQYQALSQPDFCLELARKLV 328

Query: 121 ELRFGE--------------------------------PAPARRSVEQLRGIEGSRVRAT 148
             R GE                                  P  +S++ L GIEG+     
Sbjct: 329 ACR-GEGQRKFLMRGKRNKKGDSLALEKTIAQMKAVLKQVPQIQSLDSLLGIEGNLAALY 387

Query: 149 YALLAKQY------GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAP 202
           +  L+          + ++GR   P      D  N  +S   S L      AILA G  P
Sbjct: 388 FGALSNLLAENAPESLLFSGRNRRPPK----DRFNALLSFGYSLLIKDVMNAILAVGLEP 443

Query: 203 AIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKT 260
           A+GF H  +  +     D+ +I +   V         R+  +   +  +  + ++ S   
Sbjct: 444 ALGFYHQPRTQAPPLALDLMEIFRVPLVDMPVVTSINRSQWDIQADFDVRGQQVWLSDSG 503

Query: 261 LAKLIPLIED 270
             K I L E 
Sbjct: 504 RRKFINLYEQ 513


>UniRef50_D0MKV7 CRISPR-associated protein Cas1 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MKV7_RHOM4
          Length = 553

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 42/301 (13%), Positives = 101/301 (33%), Gaps = 36/301 (11%)

Query: 6   LNPIPLK-DRVSMIFLQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
              +P + DR+ +  L  G  +       ++  +     H  +  ++ + +    +++  
Sbjct: 216 RRLVPSRNDRLPLYVLSQGSVVKRKGAQLLVQTQDDKDQHFRLIDLSRVSIFGNVQITTQ 275

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE-- 121
           A+R   +    + +   AG  +          +   + Q ++A DE   L + R +    
Sbjct: 276 AIRALVEHNIPVFFHSYAGRMLARLVSMYDVNAPVRVAQFEVAADETKSLAIARAIVTGK 335

Query: 122 -----------------------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAK--QY 156
                                   R    A    S+++L GIEG+  R  +   ++  ++
Sbjct: 336 IKNQRTLLRRNQRTRSERVLRELSRLAREARRASSLDELLGIEGAAARLYFRQFSRMLRH 395

Query: 157 GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPL 213
            + ++ +  + +  +  D +N  +S   + L      A++A G  P  G  H    G+P 
Sbjct: 396 RIAFDFKNRNRRPPK--DPVNAMLSFLYALLLKDAMCALMATGLDPYRGIFHQMRFGRP- 452

Query: 214 SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
           S   D+ +  +          +        + +  +           + K+I   E  + 
Sbjct: 453 SLALDLMEEFRPLIADSVVLRLVNTGAV-TEADFIVRGPACAMKKSAMEKVIEAYEQRMN 511

Query: 274 A 274
            
Sbjct: 512 T 512


>UniRef50_A2BKJ8 Universally conserved protein n=1 Tax=Hyperthermus butylicus DSM
           5456 RepID=A2BKJ8_HYPBU
          Length = 331

 Score = 80.4 bits (197), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 92/279 (32%), Gaps = 51/279 (18%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGT-RVSHAAVRLAAQVGTLLVWVGEAG 82
           +I V  G  V  +       +       ++L  G+  VS  A+R  A++G  LV +G+ G
Sbjct: 13  RIYVRRG-VVYAEAPSGEKAVVTADTELVVLATGSVSVSGRALRRLAELGVRLVVLGQRG 71

Query: 83  ----------------------VRVYASGQPGGARSDKLLY----QAKL--ALDEDLR-- 112
                                  RV A+G+     ++ +      QAKL   L +  R  
Sbjct: 72  QVVAEHRPVDRVNRTIEARMEQYRVKATGEALYYAAEMVYAKIVNQAKLLRYLAKSRREP 131

Query: 113 ------LKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYD 166
                  +V      LR         + E +R IE    R  +  +A+     + GR   
Sbjct: 132 WLRDAGYRVEGHADRLRQIIENEEPTTPEVIRSIEAQAARDYWDAIAQIAPTPFPGR--- 188

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADII- 223
                  D +N  +S   + LY +   A+  AG  P  GF+H  +    S  YD AD   
Sbjct: 189 --QPRGEDHLNMALSYGYAILYSIAHDALTVAGLDPYAGFLHADRSGRPSLTYDYADTYK 246

Query: 224 -----KFDTVVPKAFEIARRNPGEPDREVRLACRDIFRS 257
                K     P+  +      G      R     +   
Sbjct: 247 PIAVDKPLLTAPRKTDCLDTYMGALTYNARRCIATLVLE 285


>UniRef50_A6UVX9 CRISPR-associated protein Cas1 n=2 Tax=Methanococcales
           RepID=A6UVX9_META3
          Length = 334

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 22/112 (19%), Positives = 42/112 (37%), Gaps = 8/112 (7%)

Query: 120 FELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTIN 177
           +     +  P R   + + GIEG   +  +  +         +  R   P      D  N
Sbjct: 150 YTNNIDDKLPHREIKDTIIGIEGIASKYYFEGINHALPKNYKFKERSRRPAR----DKFN 205

Query: 178 QCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDT 227
             ++     LY + E  ++ AG  P +GF+H       + VYD+ ++ +   
Sbjct: 206 ALLNYGYGMLYPMVEKCLIVAGLDPYVGFIHADNYNKTTLVYDVIEMYRAHI 257


>UniRef50_C1XN81 CRISPR-associated protein Cas1 n=2 Tax=Meiothermus
           RepID=C1XN81_MEIRU
          Length = 323

 Score = 79.3 bits (194), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 55/291 (18%), Positives = 102/291 (35%), Gaps = 32/291 (10%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           + +  G   +         +P   V  +++    R++  A+    + G  +++    G +
Sbjct: 12  LRLSQGRLRVELDEQTLAELPARKVRGVVVWGNVRLTTPALAFLLRQGVPVLYATLEG-Q 70

Query: 85  VYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG------------------- 125
           +Y   Q   + + ++L    LA    L L     + +LR G                   
Sbjct: 71  LYGQAQAPQSLAPEVLRAQLLAQQNPLPLAQGFLLGKLRSGQMLLERLARQAPITPQQAE 130

Query: 126 -----EPAPARRSVEQLRGIEGSRVRATYALLAKQYG-VTWNGRRYDPKDWEKGDTINQC 179
                E  P  RS+E LRGIEG+  RA +A L        ++GR   P      D +N  
Sbjct: 131 IEAALEALPQARSLEALRGIEGNAARAYFAGLQAVLAPYGFSGRNRRPP----TDAVNAA 186

Query: 180 ISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIAR 237
           +S     L G    A+  AG  P +G +HT      +  +D+ +  +   V         
Sbjct: 187 LSYGYMVLLGRVLLALGIAGLHPELGLLHTEGRRVPALAFDLMEEFRVSVVDAVVIAAFL 246

Query: 238 RNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQP 288
           R+   P +        ++ +      L+  +E+  +     P    +  Q 
Sbjct: 247 RSELTPQQHSEARNGGVYLNEAGRKALLRRLEERFSQEAQHPKGFRKPYQE 297


>UniRef50_A8UXX8 Putative uncharacterized protein n=1 Tax=Hydrogenivirga sp.
           128-5-R1-1 RepID=A8UXX8_9AQUI
          Length = 290

 Score = 78.9 bits (193), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 45/272 (16%), Positives = 104/272 (38%), Gaps = 26/272 (9%)

Query: 13  DRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
            R+ +++    ++        +   + I + +PV  V  I+   G  +S  A+ L  Q  
Sbjct: 2   KRIVVVY-SSARVSRSGERVKISTFS-INSSLPVRYVEAIVAFGGLELSSHALSLLMQNN 59

Query: 73  TLLVWVGEAG-VRVYASGQPGGARSDKLLYQAKLALDE---------DLRLKVVRKMFEL 122
             + ++ + G ++     +   + +   + Q +  + +           +++ + + F L
Sbjct: 60  VPVFFLTKLGALKAVLWTKILSSNTSNRIRQYEKYVRDPFGVAKEIVRAKIRTIEREFGL 119

Query: 123 RFGEPA---PARRSVEQLRGIEGSRVRATYALLAKQ---YGVTWNGRRYDPKDWEKGDTI 176
           +            + E+L GIEG+  R  +   ++     G ++  R Y P      D +
Sbjct: 120 KLNNLISSLERAGTKEELLGIEGTASRLMFERFSQNIELSGFSFRERAYHPP----PDPV 175

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPKAFE 234
           N  +S + +  Y ++       GY P I F+HT  G  L+   DI + ++          
Sbjct: 176 NALLSLSYTFTYALSLPLTTLMGYDPYISFLHTRSGSHLALCSDIMEPVRPVLTKRLEEP 235

Query: 235 IARRNPGEPDREVRLACRDIFRSSKTLAKLIP 266
           I RR   +  ++        +   +++ K + 
Sbjct: 236 ILRRVFTK--KDFNRERAACYLKKESMPKFLN 265


>UniRef50_UPI00016C522C CRISPR-associated protein Cas1/Cas4 n=1 Tax=Gemmata obscuriglobus
           UQM 2246 RepID=UPI00016C522C
          Length = 571

 Score = 78.1 bits (191), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 45/276 (16%), Positives = 85/276 (30%), Gaps = 38/276 (13%)

Query: 7   NPIPLKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
             IP+ D  ++++LQ     +       V+  +    T +P+ ++  +++    +VS  A
Sbjct: 226 KVIPMTDDGAVLYLQEPGTSVGKRSEHLVVKKEGQELTRVPMHAIRQVVVCGNVQVSTQA 285

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRK------ 118
           +   A     + +V   G  + +              Q +   D    L + +       
Sbjct: 286 LETLAANDIAVAYVTGHGRFIGSFVPAPAKNVSLREAQFRTFNDPSACLDLAKAVVRAKL 345

Query: 119 -------MFELR------------------FGEPAPARRSVEQLRGIEGSRVRATYALLA 153
                  M  LR                        A+ SVE + GIEG      +    
Sbjct: 346 SNQRALLMRSLRGEGEARGSHEYSAKGIYGLLGALDAQTSVESVLGIEGQGAALYFGDFG 405

Query: 154 KQYGVTWNGRRYD---PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG 210
           +       G+ +D          D +N  +S A + L     +     G+ P  GF H G
Sbjct: 406 RFLKQPPTGKGFDFTTRNRRPPRDPVNALLSFAYAMLAKDCFSVACTVGFDPYKGFFHVG 465

Query: 211 K--PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           +    S   D+ +  +          +       PD
Sbjct: 466 RHGKPSLALDLMEEFRPVIADSVVLTLINNEALTPD 501


>UniRef50_B9K7F7 CRISPR-associated protein, Cas1 family n=1 Tax=Thermotoga
           neapolitana DSM 4359 RepID=B9K7F7_THENN
          Length = 329

 Score = 78.1 bits (191), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 51/286 (17%), Positives = 95/286 (33%), Gaps = 35/286 (12%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGI---RTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +      G++   +   ++  +      R  IPV ++  I       ++   +  AA+  
Sbjct: 7   NYYVFSSGRVKRHENTILIEYQKAGMQQRKFIPVENIDQIFFLGEVDLNSKFLDFAAKNN 66

Query: 73  TLLVWVGEAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVRKMFE---LRFGE 126
            +L +    G   Y             + L+ Q +  LD + RL + RK  E     F  
Sbjct: 67  IVLHFFNYYG--YYTGSFYPREKFISGELLVRQVEHYLDSEKRLTLARKFVEGAVHNFKR 124

Query: 127 PAPAR------------------RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPK 168
               R                  +++ +L   E    +  Y+   +  G  +  R   P 
Sbjct: 125 NIEKRGFDITDKISEYLERTKYAKTIPELMSCEAHARKLYYSTWEEITGWPFEERSMQPP 184

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFD 226
             E    +N  IS   S  Y +    +      P I ++H    K  S   DIA+I K  
Sbjct: 185 LNE----LNALISFGNSLTYSIVLKELYFTHLNPTISYLHEPGTKRFSLALDIAEIFKPI 240

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
            V    F++      + ++      R +F + +     I   E++L
Sbjct: 241 FVDRIIFKLINLKKIDREKHFLQEARGVFLNEEGRRLFIEEFENML 286


>UniRef50_A9GDF7 Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So
           ce 56' RepID=A9GDF7_SORC5
          Length = 365

 Score = 77.0 bits (188), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 61/280 (21%), Positives = 101/280 (36%), Gaps = 35/280 (12%)

Query: 10  PLKDRVSMIFLQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           P  +R S+  + +G +I     AF + ++ G RT I    V+ I++    +++  A+RL 
Sbjct: 25  PDTERRSLHVVSHGARIGRASDAFEVTEREGERTRIGAREVSDIVVHGHAQITTQALRLC 84

Query: 69  AQVGTLLVWVGEAG--VRVYASGQPGGARS----------------DKLLYQAKLALDED 110
           A     + +VG  G  V V++ G  G  R                  + L  AK+ +   
Sbjct: 85  AAEEIAVHFVGAGGAHVGVFSGGSSGVQRRIRQFRGLTDDVFAIGLARRLVMAKIEMQLR 144

Query: 111 LRLKVVRKMFELRFGEPAP------------ARRSVEQLRGIEGSRVRATYALLAKQYGV 158
             L+  RK   LR G   P                   L G EG+  R  +  LA     
Sbjct: 145 HVLRASRKDEALRAGLDEPIESLRGGLRRAAKAADRTSLMGQEGNAARGYFGALAALVHP 204

Query: 159 TW--NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSF- 215
                 R          D  N  +S   + LY    +AIL  G  P  G +H  +  +F 
Sbjct: 205 DAGDALRPRGRSRRPPEDRFNALLSFGYTLLYRDVLSAILRVGLEPGFGVLHQPRSAAFP 264

Query: 216 -VYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDI 254
              D+ ++ +   V         R   + +R+  +  R +
Sbjct: 265 LALDLTELFRVPVVDMAVLGAVNRRTFDAERDFVITGRQV 304


>UniRef50_C1XWQ6 CRISPR-associated protein, Cas1 family n=3 Tax=Thermaceae
           RepID=C1XWQ6_9DEIN
          Length = 326

 Score = 77.0 bits (188), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 48/282 (17%), Positives = 94/282 (33%), Gaps = 47/282 (16%)

Query: 15  VSMIF-LQYGQIDVIDGAFVLIDKT--GIRTHIPVGSVAC---IMLEPGTRVSHAAVRLA 68
           + +++ L+ G +    G   +  +   G  T +    +     ++L     V+ A ++  
Sbjct: 1   MGVVYVLEDGYLAKDGGTLKVSKRGPGGGETLLEKPLIGVEEIVVLGNAV-VTPALLKHC 59

Query: 69  AQVGTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKM-------- 119
           A+    L +V   G R +A   +     +   + Q    LD   +L + R+         
Sbjct: 60  AEENIGLHYVSTGG-RYFAGLTRTPAKNAPARVAQFAAHLDPTRKLALARRFVLGKLRNS 118

Query: 120 ------------FELRFG-EPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRR 164
                        E+R+             LRG+EG+     +   A     G  ++ R 
Sbjct: 119 LTLLRRNGAEGWEEIRWAIGELDKAADEGALRGLEGNAADVYFRSYAALLPEGFRFSERS 178

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADI 222
             P      D  N  +S A + L    E+A+  AG  P +G++H  +    S   D+ + 
Sbjct: 179 RRPPR----DPANSLLSLAYTFLAKECESALQVAGLDPYVGYLHEVRYGRASLALDLMEE 234

Query: 223 IKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKL 264
            +          +            R    + F  ++   KL
Sbjct: 235 FRSILADSVVLSLLNN---------RRLTLEDFDDAEGYPKL 267


>UniRef50_A1A2M8 CRISPR-associated DNA polymerase n=14 Tax=Bacteria
           RepID=A1A2M8_BIFAA
          Length = 343

 Score = 76.6 bits (187), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 46/269 (17%), Positives = 86/269 (31%), Gaps = 46/269 (17%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            +  +   + + +   V+         +P+ S+  IM       S A +    ++G  + 
Sbjct: 9   FVMTEDAYLALENDNVVIYQNDQTLAKVPLRSIEGIMCFSYKGASPALMGRCGKLGVSMA 68

Query: 77  WVGEAGVRVYASGQPGGARSDKLLY-QAKLALDEDLRLKVVRKM---------------- 119
           +    G   Y S      R+  L   Q ++A DE   L+  +                  
Sbjct: 69  FYSPRG-HYYCSVLGEENRNVLLRREQFRVADDEQKSLRYAKSFIVGKLYNAKWVLERTK 127

Query: 120 --FELRFGEPAPA---------------RRSVEQLRGIEGSRVRATY-----ALLAKQYG 157
               LR      A                 ++++LRG+EG   +  +      +L  +  
Sbjct: 128 RDHALRVNIDRLAEQSGKLSAALSKARKSLTIDELRGVEGLAAKDYFYAFDDLVLKNKDD 187

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SF 215
             +  R   P      D +N  +S   S L     AA+   G  P +GF+HT +P   S 
Sbjct: 188 FFFTSRSRRPP----LDRLNALLSFCYSILTNDCIAALQGVGLDPYVGFMHTDRPGRASL 243

Query: 216 VYDIADIIKFDTVVPKAFEIARRNPGEPD 244
             D+ +  +          +      +P 
Sbjct: 244 ALDLVEEFRPVLADRFVLTLVNTGAVKPG 272


>UniRef50_D0YU98 Crispr-associated protein Cas1 n=1 Tax=Mobiluncus mulieris 28-1
           RepID=D0YU98_9ACTO
          Length = 309

 Score = 76.6 bits (187), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 45/228 (19%), Positives = 80/228 (35%), Gaps = 30/228 (13%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
            G +   +GA V+  + G    +P+  VA ++    TR S  +V    +  T +++    
Sbjct: 18  RGFVTSTEGALVVRPEEGEERRVPISDVAVVLFGVDTRFSAGSVHRILKNDTAVIFCDWK 77

Query: 82  GVRVYASGQPGGARSDKLLYQ-AKLALDEDLRLKV-VRKMFELRFGEP-------APARR 132
           GV  Y    P G  +     Q A+       R  V  R +     G+         P  +
Sbjct: 78  GVP-YGHAYPWGDHTRVGARQIAQANASIPARKSVWARLIKSKVLGQAEVLEFFGRPNGK 136

Query: 133 SVEQL---------RGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDT--INQCIS 181
            +++L           IEG   R  +  L       W+ + +       GD   IN  + 
Sbjct: 137 RLKELVKDIRSGDPSNIEGQAARIYWESL-------WDDQDFRRTPGAGGDIFTINAMLD 189

Query: 182 AATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDT 227
              + L G    A+ A+G   ++G  H G+   +    D  +  +   
Sbjct: 190 YGYTILRGHAMRAVAASGLISSLGVAHRGRSNPWNLADDFIEPFRPAI 237


>UniRef50_C3MX12 CRISPR-associated protein Cas1 n=11 Tax=Sulfolobaceae
           RepID=C3MX12_SULIM
          Length = 304

 Score = 76.2 bits (186), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 47/298 (15%), Positives = 102/298 (34%), Gaps = 50/298 (16%)

Query: 6   LNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAV 65
           +  + + +  + I+++   + +  G          +  I    V  I++     +S +A+
Sbjct: 1   MRTLVISEYGAYIYVKKNMLVIKKG--------DNKVEISPSEVDEILITASCSISTSAL 52

Query: 66  RLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG 125
            LA   G  ++++          G    +   + +   K          V +K  ++R+G
Sbjct: 53  SLALTHGISVMFLNSRDTP---WGILLPSVITETVKTKKA----QYETIVAKK--DIRYG 103

Query: 126 EPAPARRSVEQ-------------------LRGI-EGSRVRATYALLAKQYGVTWNGRRY 165
           E   + +   Q                   L G  E +  R  +  +++   +      +
Sbjct: 104 EEIISSKIYNQSVHLKYWTRLTGTRNDYKELLGKDEPTAARIYWRNISQ---LLPKDIGF 160

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADII 223
           D +D +  D  N  ++ + + LY      ++ AG  P +GF+H  +P   S VYD +++ 
Sbjct: 161 DGRDVDGVDQFNMALNYSYAILYNTIFKYLVIAGLDPYLGFIHKDRPGNESLVYDFSEMF 220

Query: 224 KFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPA 281
           K   +        R          RL  +D      +   L  LI   +     +   
Sbjct: 221 KP-YIDFLLVRALRSG-------FRLKVKDGLIEENSRGDLAKLIRKGMEEKVKEESD 270


>UniRef50_C4G3M4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G3M4_ABIDE
          Length = 340

 Score = 76.2 bits (186), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 54/304 (17%), Positives = 109/304 (35%), Gaps = 40/304 (13%)

Query: 16  SMIFLQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
            +  ++ G +I  I G F+L  K G    +P   +  I +   + ++  A++   +    
Sbjct: 9   CLYVVEQGSKIKHIGGQFILEVKDGENRVVPDEILESISIFGNSVLTTQAIKACLEKNIN 68

Query: 75  LVWVGEAGVRVYASGQPGGARS-DKLLYQAKLALDEDLRLKVVR--------------KM 119
           + ++   G R +       A + D+L  QA L+ + D  LK  +              + 
Sbjct: 69  VSFLSTKG-RYFGKLMSNTATNPDRLKAQAYLSDNIDECLKFAKIILKAKINNQDVILRR 127

Query: 120 FELR--------------FGEPAPARRSVEQLRGIEGSRVRATYALLAK--QYGVTWNGR 163
           +                 + E     + + ++ G EG   R  +  L+K  +    ++GR
Sbjct: 128 YAKSSEADISSHIKDLKIYEEHIEKGKDINKIMGYEGIAARTYFEALSKLIKPEFKFSGR 187

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIAD 221
              P      D  N  +S   S +Y    + I     +P IGF+H  K    + V D+ +
Sbjct: 188 NKRPPK----DAFNSMLSLGYSLIYNEIFSEIENRNLSPYIGFIHKLKDRHPALVSDLIE 243

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDI-FRSSKTLAKLIPLIEDVLAAGEIQPP 280
             +   V      + + N    +   +    +  F S   + +++  IE+ L +      
Sbjct: 244 EWRAVLVDATMMSLIQGNEILIEEFTKDEYSEAVFISDLAVKQIVRKIENKLRSQNNYLE 303

Query: 281 APPE 284
              E
Sbjct: 304 YLNE 307


>UniRef50_C9M4E6 CRISPR-associated protein cas1 n=1 Tax=Lactobacillus helveticus DSM
           20075 RepID=C9M4E6_LACHE
          Length = 332

 Score = 75.4 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 48/291 (16%), Positives = 91/291 (31%), Gaps = 41/291 (14%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
                 G+++  D    L    G    + +     I L      +   +   AQ+   + 
Sbjct: 7   YYLFSSGELERKDNTVRLTRSDGKYKDLKIEVTRDIYLFGEVSTNTKCLNYLAQMKIPVH 66

Query: 77  WVGEAGVRVYASGQPG---GARSDKLLYQAKLALDEDLRLKVVRKM-------------- 119
           +    G   Y               L+ Q +   D   RL   +K               
Sbjct: 67  FFNYYG--FYTGSFYPKEQNVSGTLLIQQVQAYTDPKRRLYYAKKFVLGAAKNLLRNLKY 124

Query: 120 FELR---FGEPAPARRSV----------EQLRGIEGSRVRATYALLAKQY--GVTWNGRR 164
           ++ R     +      S+          E+L G+EG+  R  YA     +   V ++ R 
Sbjct: 125 YQRRGRNLDDSIKEITSLIRQIDQVHDVEELMGVEGTIHRRYYASWQSVFIPDVDFSKRV 184

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADI 222
             P D    + +N  IS     +Y    + I      P I ++H+   +  S   DI++I
Sbjct: 185 RRPPD----NMVNTLISFLNGLMYTTCLSEIYVTQLNPTISYLHSPMDRRFSLCLDISEI 240

Query: 223 IKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
            K   V    F +  +N    + +        + S K+   ++   +  + 
Sbjct: 241 FKPMIVDRLIFSLINKNMIS-EEDFNKESNYCYLSEKSKRIIVSEYDKYMK 290


>UniRef50_A6UNF5 CRISPR-associated protein Cas1 n=1 Tax=Methanococcus vannielii SB
           RepID=A6UNF5_METVS
          Length = 322

 Score = 75.4 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 8/95 (8%)

Query: 134 VEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
            +Q++G+EGS  +  + +L+K       +NGR   P      D  N  ++     LY   
Sbjct: 155 RDQIQGLEGSVSKIYFRVLSKSLPKKYQFNGRSRKPAK----DYFNCMLNYGYGMLYSEI 210

Query: 192 EAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK 224
           E   + +G  P IG +HT      SFV+D  +  +
Sbjct: 211 EKICIISGIDPTIGILHTDGQNRKSFVFDYIEKYR 245


>UniRef50_A5UXM3 CRISPR-associated protein, Cas1 family n=4 Tax=Chloroflexaceae
           RepID=A5UXM3_ROSS1
          Length = 332

 Score = 75.4 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 45/257 (17%), Positives = 90/257 (35%), Gaps = 39/257 (15%)

Query: 18  IFL-QYGQIDVI-DGAFVLIDKTGIRTHIPVGSVA-CIMLEPGTRVSHAAVRLAAQVGTL 74
           +++ + G +    D   ++       + +P+  +   +++  G ++S A +    + G  
Sbjct: 4   LYIQEQGVMVRKRDNQVLITKDGQTLSEVPLAKIDQVVLMGRGVQLSTALLIDLLERGIP 63

Query: 75  LVWVGEAGVRVYASGQPGGAR-SDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA----- 128
           + +  + G R YA+   G +R  D  + Q +     D  L++ + +   +          
Sbjct: 64  VTFTNQHGSRHYATLTAGPSRFGDLRIRQMQFVGAPDRALRLAKDIVSAKLTNQRRLLAA 123

Query: 129 ---PARRS-----------------VEQLRGIEGSRVRATYALLAKQYGVTWN--GRRYD 166
              PA  +                 V+ LRG EG+   A +          W   GR + 
Sbjct: 124 TGWPAAATAIAQIDAALTAAANAPHVDMLRGHEGAAAAAYFGAWRASLPPVWGFGGRAFY 183

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADII 223
           P      D IN  +S   +        A+   G    +G  H    G+P S   D+ +  
Sbjct: 184 PP----PDPINAMLSFGYTLALHDVITAVQITGLDTYLGVFHVIEPGRP-SLALDLLEEF 238

Query: 224 KFDTVVPKAFEIARRNP 240
           +   V     ++ R N 
Sbjct: 239 RPLIVDRLVIDLVRTNA 255


>UniRef50_B7IHY4 Cas crispr-associated protein Cas1 n=4 Tax=Bacteria
           RepID=B7IHY4_THEAB
          Length = 330

 Score = 75.0 bits (183), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 51/282 (18%), Positives = 96/282 (34%), Gaps = 45/282 (15%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           G++   D         G +  +P+ ++  + +     ++   +  A++ G L+ +    G
Sbjct: 11  GELKRKDNTICFESSEGKKY-LPIENINNLWIFGEVELNKRFLDFASENGILIHFFNFYG 69

Query: 83  VRVYAS---GQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------------FELR-- 123
              Y      +        +L QA+  LD + R+K+ RK               ++ R  
Sbjct: 70  --YYTGTFYPREHLNSGFVILKQAEHYLDNEKRIKLARKFVEGAVENLLVVLKYYKNRGY 127

Query: 124 -FGEPAP----------ARRSVEQLRGIEGSRVRATY----ALLAKQYGVTWNGRRYDPK 168
              +             + + VE L   EG+ +R  Y      + K+    +  R   P 
Sbjct: 128 ELEDEIDDIKNKKEGIYSSQDVETLMSFEGN-IRDIYYKCFDKITKKEEFAFEKRSRRPP 186

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFV--YDIADIIKFD 226
                + +N  IS   S LY      I      P IG++H+     F    D+A+I K  
Sbjct: 187 ----LNKMNSLISFGNSLLYTTVLGEIYQTQLDPRIGYLHSTNNRRFTLNLDVAEIFKPS 242

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
            V    F +  +N     ++       I  ++    K I   
Sbjct: 243 IVDRVIFSLVNKNV-LSSKDFDKQLNGIVLNNSGKKKFIEEY 283


>UniRef50_B7C8S2 Putative uncharacterized protein n=2 Tax=Eubacterium biforme DSM
           3989 RepID=B7C8S2_9FIRM
          Length = 329

 Score = 75.0 bits (183), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 46/258 (17%), Positives = 87/258 (33%), Gaps = 38/258 (14%)

Query: 13  DRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
            +V  ++ + G +   D + VL  K      IP+  V  I+      ++   + L  +  
Sbjct: 2   KKVVYLY-KSGNLKRKDNSLVLESKDKDDY-IPIEQVDMIICFSEVSLNKRVLALLNKYE 59

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR--------------K 118
            L+++    G  +             L+ Q     DE  RL + +              K
Sbjct: 60  VLILFYNFYGNYIGRYAPKDYKDGRVLVNQVNKYRDESQRLYISKSILKASIKNMLSVLK 119

Query: 119 MFELRFGEPAPARRSVEQLRGI-------------EGSRVRATYALLAKQYG---VTWNG 162
            +  +        R +E L G+             E +  +  Y +           +  
Sbjct: 120 YYRKKGKNLDELIRKLEDLVGMASDIETMNELMLIEANAKQTYYKMFDVVLENEEFKFQK 179

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIA 220
           R  +P   E    +N  +S   + LYG+  + +  +   P I F+H  +    S  YD+A
Sbjct: 180 RTKNPPQNE----VNAMLSYGYTLLYGIILSILDRSSLFPQISFIHSLSKNSDSLQYDLA 235

Query: 221 DIIKFDTVVPKAFEIARR 238
           DI K   +      + R+
Sbjct: 236 DIFKPVYIDRMVLRLIRK 253


>UniRef50_A8ABK8 CRISPR-associated protein Cas1 n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8ABK8_IGNH4
          Length = 305

 Score = 75.0 bits (183), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 55/257 (21%), Positives = 91/257 (35%), Gaps = 48/257 (18%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            +  + G++ V DG     +  G   ++       I+      V+ AA+R   ++G  LV
Sbjct: 4   FVISEPGKLFVKDGGLAFANSKGEVAYLANLYDVIILATSKVSVTGAALRAMGRLGVDLV 63

Query: 77  ---WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM-------------- 119
              W G    R   S       +   L Q ++ L +   LK  + M              
Sbjct: 64  VLEWNGRPSGRF--SSPVPNKSALARLKQYEVVL-KGEGLKYAKPMIVRKIIEQGRTLRY 120

Query: 120 --------------FEL-RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRR 164
                         +EL +    A +  S E LR +E    R  + LL++ +   + GR 
Sbjct: 121 FAKTKRMKWLREASYELEKLSADASSAGSPEALRAVEAQAARLYWGLLSEAFP-EFPGRE 179

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH---TGKPLSFVYDIAD 221
                 E  D  N  I+ +   LY     A+   G  P  G  H   +G+  + VYD ++
Sbjct: 180 -----HEGCDPYNSAINYSYGILYSYAFKALSVTGLDPYAGLFHAIKSGRE-ALVYDFSE 233

Query: 222 IIK---FDTVVPKAFEI 235
             K       +P A E+
Sbjct: 234 QFKPLVDRRALPLAHEL 250


>UniRef50_A1BI39 CRISPR-associated protein Cas1 n=5 Tax=Chlorobiaceae
           RepID=A1BI39_CHLPD
          Length = 731

 Score = 75.0 bits (183), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 48/300 (16%), Positives = 100/300 (33%), Gaps = 49/300 (16%)

Query: 18  IFL-QYGQIDVIDGAFVLIDKTGIRT-HIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           ++L + G +   DG    I+K G     + V  +  +++     ++   ++   Q    +
Sbjct: 392 LYLQEQGSLMRKDGERFSIEKDGSVINEVIVRRIEQVVIFGNVALTTPVMQYCLQNEIPV 451

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLAL----DEDLRLKVVR-----------KMF 120
            ++ + G + +  G+     +D    Q +       DE   L+  R            M 
Sbjct: 452 TFLSQHG-KYF--GRLEATTADNAEMQ-RFHFLRSIDEPFALETARSIVAAKISNSKTMI 507

Query: 121 ELR------------------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQY 156
             R                            A A   ++ LRGIEG      +      +
Sbjct: 508 RRRKTVVQDRDSTLQNKMAYNLDIMADLALKAEASTDIDALRGIEGKASALYFECYGMLF 567

Query: 157 G--VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL- 213
              + ++ R +        D +N  +S   + L+    + + A+G  P IGF+H  +   
Sbjct: 568 SKNLPFHTRSFLRVRRPPTDPVNSLLSFGYTMLHTNIFSMVQASGLNPYIGFLHAERKGN 627

Query: 214 -SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
            + V D+ +  +        + + R    E D   R      F S+    + + + E  +
Sbjct: 628 PALVNDLVEEFRTIVDSLVLYTLNRGLLQEKDFYYRKDEPGCFLSNDARKRFLNIFETRM 687


>UniRef50_Q53W21 Putative uncharacterized protein TTHB145 n=3 Tax=Thermus
           thermophilus RepID=Q53W21_THET8
          Length = 315

 Score = 73.9 bits (180), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 55/265 (20%), Positives = 88/265 (33%), Gaps = 26/265 (9%)

Query: 45  PVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQ-- 102
           P   V  + L    R+S  A+    + G  + +    G     +G         L  Q  
Sbjct: 32  PARQVRSVALWGNVRLSTPALVFLLRQGVPVFFYSLEGFLHGVAGAYPDPHPAHLRAQFA 91

Query: 103 ------AKLALDEDLRLKVVRKMFELRFGEP---------APARRSVEQLRGIEGSRVRA 147
                 A+  +   LR  +   +   R  E          A     +E+LRG EG   R 
Sbjct: 92  AEGLPLARAFVVGKLRSALAL-LERHRLPEAGGVVEALARAEGASELERLRGAEGEGSRV 150

Query: 148 TYALLAKQYG-VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGF 206
            +  LA+  G   + GR   P      D +N  +S   + L G    A+  AG  P +GF
Sbjct: 151 YFQGLARLLGPYGFGGRTRRPPR----DPVNAALSYGYALLLGRVLVAVRLAGLHPEVGF 206

Query: 207 VHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKL 264
           +H     S     D+ +  +   V        RR    P     +    ++ + +   +L
Sbjct: 207 LHAEGRRSPALALDLMEEFRVPVVDQVVLSAFRRGLLTP-SHAEVREGGVYLNEEGRRRL 265

Query: 265 IPLIEDVLAAGEIQPPAPPEDAQPV 289
           I L E+ L  G   P    +     
Sbjct: 266 IQLFEERLLEGVSHPLGFRKPLGET 290


>UniRef50_C2GEC7 Crispr-associated protein Cas1 n=2 Tax=Corynebacterium
           RepID=C2GEC7_9CORY
          Length = 533

 Score = 73.5 bits (179), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 46/275 (16%), Positives = 82/275 (29%), Gaps = 39/275 (14%)

Query: 18  IFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVW 77
           + +Q  +  + +G  ++          P+  V  +++     +S A  R        +VW
Sbjct: 210 LTVQGSRASIRNGRVIVEKAGERLADAPLERVQGVVIHGNVDISSALHRNFLWHNVPVVW 269

Query: 78  VGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------LRFGEP 127
               G RVY    P    +     Q  +       L + R M             R G+ 
Sbjct: 270 CSTTG-RVYGYSCPTDGPNAAARVQQHVLS-SRGCLPIARGMVNAKIMNQATLLRRNGDS 327

Query: 128 A-------------PARRSVEQLRGIEGSRVRATYALLA--------KQYGVTWNGRRYD 166
                            +   QL GIEG      ++  +         Q G TW GR   
Sbjct: 328 DRTVQLLIDAGTCSLEAKDNRQLFGIEGDAAALYFSTFSTMLNKAQIDQLGWTWTGRHGR 387

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK 224
                  D IN  ++ +   L      A+L+ G  P  GF+H+      +   D+ +  +
Sbjct: 388 ----GASDPINILLNYSYGLLRAEVIRALLSCGLDPHAGFLHSSGRNKPALALDLMEEFR 443

Query: 225 FDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSK 259
                     +  R   +      +      R + 
Sbjct: 444 APVSDSVVISLINRREIKDTDFTHIHGVARLRDTG 478


>UniRef50_Q65S18 Putative uncharacterized protein n=1 Tax=Mannheimia
           succiniciproducens MBEL55E RepID=Q65S18_MANSM
          Length = 333

 Score = 73.1 bits (178), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 46/243 (18%), Positives = 90/243 (37%), Gaps = 37/243 (15%)

Query: 18  IFLQYGQIDVI-DGAFVLIDKTGIRTH-IPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++     ++  +G  ++  + G R   IP+ SV  + ++    +  + +    + G  +
Sbjct: 4   LYIDRRTTELKVNGDVLICYEKGERIATIPLASVDRLYMKGDINLQISLLSKLGEKGIGV 63

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM----------FELRFG 125
           V++     +           + + + Q  LA ++   L + + +          F  +F 
Sbjct: 64  VFLQGRKNKPMQFLPQPHNDAYRRVTQTYLADNKLFCLTLAKNIVLNKCIKQCQFLAKFI 123

Query: 126 EPAPA-----------------RRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYD 166
           E  P                  + +++ LRGIEG      +A  A      + +NGR   
Sbjct: 124 EHNPKIITFIAELQKLFNLIVKQENIDSLRGIEGRMGAIYFAAFADILPRSLGFNGRNRR 183

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIK 224
           P      D +N  +S   + LY     A+  AG  P IGF HT      S   D+ + I+
Sbjct: 184 PPK----DPVNAVLSLTYTLLYSEATLAVYGAGLDPYIGFFHTLHFGRKSLSCDLMEPIR 239

Query: 225 FDT 227
              
Sbjct: 240 PSV 242


>UniRef50_A7GY67 Crispr-associated protein Cas1 n=6 Tax=Campylobacter
           RepID=A7GY67_CAMC5
          Length = 332

 Score = 72.7 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 62/300 (20%), Positives = 102/300 (34%), Gaps = 44/300 (14%)

Query: 12  KDRVSMIFLQYGQIDVIDGAFVL--IDKTGIRTH---IPVGSVACIMLEPGTRVSHAAVR 66
            DR   I L  G++   D        D+TG  T    +P+ ++  I +     +    + 
Sbjct: 4   SDRTHFI-LSSGRLRRQDNNIYFDKFDETGGVTASKILPINAIDEIYILTRVELDTYTLA 62

Query: 67  LAAQVGTLL----VWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR----- 117
             A    LL     +    G    ++          LL Q +   D   R+ + R     
Sbjct: 63  FLADNNILLHVFSPFQSFRGNFYPSTSNSVNKSGFALLSQLRAFDDPVKRVYIAREITRA 122

Query: 118 ---------KMFELRFGEPAPARRSVE------QLRGIEGSRVRATYALL----AKQYGV 158
                    K   ++F +PAP   +++      Q+   EG+  +  Y       A Q   
Sbjct: 123 HMLNDAANCKKHGVKF-DPAPHIAALDAAADVGQIMAAEGAFQKLYYEKWNEIIADQRSF 181

Query: 159 TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFV 216
            +  R   P      D IN  IS   + +Y V  + I      P IGF+H    + LS  
Sbjct: 182 KFTVRSKRPP----ADKINSFISYVNTRIYNVCLSEIYKTELDPRIGFLHEPNYRALSLH 237

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRS---SKTLAKLIPLIEDVLA 273
            D+A+I K        F +  +           A R  F +    K   K+I  + + +A
Sbjct: 238 LDLAEIFKPILGDTLIFAMLNKKEITAKDFQTDAGRIKFSNDAIQKIEMKMISRLSETIA 297


>UniRef50_B0TFX3 Crispr-associated protein cas1 n=4 Tax=Clostridia
           RepID=B0TFX3_HELMI
          Length = 364

 Score = 72.0 bits (175), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 38/248 (15%), Positives = 82/248 (33%), Gaps = 42/248 (16%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSV-ACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV 83
           +    G  V+ +K  + T +P   V    ++  G  +S  A+    + G  +  +   G 
Sbjct: 41  LGKKSGRLVVREKGQVVTEVPFDRVEQVTVITSGASLSTDAIEECVRHGIEINLLDFRGS 100

Query: 84  RVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA------------- 130
                  PG   + K   +  LA ++   + + +     +                    
Sbjct: 101 PYAKLFAPGLTATVKTRREQLLAFNDQRSIFLAKAFVRGKIQNQINTLKYFAKYRKSARQ 160

Query: 131 -------------RRSVEQLRGIEGSRVRA----TYALLAKQYGVTWNGRRY-------- 165
                         +++++L GI+G  + A      ++  +     W+   +        
Sbjct: 161 EVYAYLQDAALLMEKNLQELTGIDGLNIDAVRGPLMSVEGRAATRYWDAVAFLLKGYVVF 220

Query: 166 -DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADI 222
              ++    D +N  ++   + L      A+L AG  P  GF+H  +P   S VYD  + 
Sbjct: 221 PGRENRGATDPVNSLLNYGYAVLEARVLGAVLQAGLDPYAGFLHVDRPGKTSLVYDFIEE 280

Query: 223 IKFDTVVP 230
            +   +  
Sbjct: 281 FRQPVIDR 288


>UniRef50_A7HMV0 CRISPR-associated protein Cas1 n=3 Tax=Thermotogaceae
           RepID=A7HMV0_FERNB
          Length = 329

 Score = 72.0 bits (175), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 53/299 (17%), Positives = 105/299 (35%), Gaps = 54/299 (18%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           L+ + S ++++               +     ++P+ +++ IM+     ++   + L + 
Sbjct: 12  LRKKSSALYIE------------PKSEDQKPIYVPLKNISSIMVFSEIEMNKKTLELFSY 59

Query: 71  VGTLLVWV---GEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR---------- 117
               + +    GE     Y          + LL Q +   D + R+ + R          
Sbjct: 60  SQVPVFFFNYNGEYIGCFY--PVEENKTGEMLLLQLQHYQDLEKRIIIAREILYGVADNI 117

Query: 118 ----KMFELRFGEPAPARRSVE-------------QLRGIEGSRVRATYALLAKQYGVTW 160
               K ++  F E       +E              L  IEG+  +  Y  L    GV +
Sbjct: 118 LKILKSYKNDFPEINEKIEMIEKLKKTYHRQEEIASLMAIEGNIRKNYYEAL----GVIF 173

Query: 161 NGRRYDPKDWEK---GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SF 215
           + + +  ++       D IN  IS   + LY V  + I      PAI F+H       S 
Sbjct: 174 SKKDFTFQERTARPPADEINAMISFGNTILYNVVLSEIFKTSLEPAISFLHEPNKRKFSL 233

Query: 216 VYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
             DIA+I K   V      +  R+  + D + +     ++ +     K +  +E+ L+ 
Sbjct: 234 QLDIAEIFKPIIVDRTILTLVNRSMIKKD-DFKKVEGGVYLNETGKKKFVKALEEKLSE 291


>UniRef50_C1DUM1 Crispr-associated protein Cas1 n=18 Tax=Bacteria RepID=C1DUM1_SULAA
          Length = 331

 Score = 72.0 bits (175), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 45/254 (17%), Positives = 82/254 (32%), Gaps = 35/254 (13%)

Query: 23  GQIDVIDGAFVLIDKTGI---RTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVG 79
           G+I   +       +      +T +P+  +  I +     ++  A+   +Q    + +  
Sbjct: 11  GRIRRKENTVYFETEKDGESLKTPLPINDIDTIFIFGEVDINTKAINYLSQYDIPMHFFN 70

Query: 80  EAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVRKMFE---------LRFGEP 127
             G   Y+              L+ Q K  +D+  R  +     E         LR    
Sbjct: 71  YYG--YYSGSFLPRKKNVSGSLLVEQVKHHIDDSKRQMLAISFIEGAVHHILRNLRKSGI 128

Query: 128 APAR---------------RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEK 172
           +                  +++E+L  IEG+ +R  Y  L        +      +    
Sbjct: 129 SVENFQNIEKDLLPKIFETKTIEELMAIEGN-IREHYYQLFNTVIKNKDFFIEKREKRPP 187

Query: 173 GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVP 230
            + IN  IS   S +Y      I      P I ++H+   K  S   DIA+I K   + P
Sbjct: 188 TNPINALISFGNSIMYNTVLTEIYRTQLDPTISYLHSPQEKRFSLSLDIAEIFKPFIIDP 247

Query: 231 KAFEIARRNPGEPD 244
             F + +      D
Sbjct: 248 LIFNLIKTGQITID 261


>UniRef50_B8GDW2 CRISPR-associated protein Cas1 n=1 Tax=Methanosphaerula palustris
           E1-9c RepID=B8GDW2_METPE
          Length = 327

 Score = 72.0 bits (175), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 42/268 (15%), Positives = 88/268 (32%), Gaps = 35/268 (13%)

Query: 31  AFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQ 90
             +++ K G  T  P+G V  +++  G  +  A ++     G  + +    G  V     
Sbjct: 26  RLLIVQKNGTTTEYPIGDVHHLLVVGGHTIHSAVLQHMQNAGNWVSFFAADGTPVGLIRP 85

Query: 91  PGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF-------------------------- 124
           P     +++    + A      L + R     R                           
Sbjct: 86  PEDRVDEQVRAIQRHAPAHSYALGITRAALGRRLQVIGETTVVTGESPLYQGELEVLQDA 145

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTINQCISA 182
            +      +++++R +        Y ++A+    G  +  R   P      D +N  +S 
Sbjct: 146 RQELEYLVTLDEIRRLHRLATDMYYEIMARTIPKGTGFRRRTARP----YMDPVNTMLSF 201

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           +   L GV    +  A     IG +H G   + V D+ ++ K   V    F + R+    
Sbjct: 202 SYGILSGVCAVHLAGAHLDANIGLLHQG-ERALVRDLTELFKPQMVDQPIFALVRQGITA 260

Query: 243 PDREVRLACRDIFRSSKTLAKLIPLIED 270
            D E  +       S   + +++  ++ 
Sbjct: 261 SDYE--IGESRCTLSDALIRRMLLHLQT 286


>UniRef50_D2PIT7 CRISPR-associated protein Cas1 n=2 Tax=Sulfolobus
           RepID=D2PIT7_SULIS
          Length = 255

 Score = 71.6 bits (174), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 8/114 (7%)

Query: 134 VEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEA 193
           +  LR IE    R  +  L K     + GR+         D IN+ I  A S +Y +   
Sbjct: 93  LNSLRLIEAEYGRKAWDELKKFLPREFTGRK-----PRNEDPINRAIDYAYSIIYSLCTH 147

Query: 194 AILAAGYAPAIGFVHTGKP--LSFVYDIADIIKFDTVVPKAFEIARRNPGEPDR 245
           A++A G  P  G +H+  P  LSF YD +++ K    V      +RR     D+
Sbjct: 148 ALIAVGLDPYAGVMHSNFPGRLSFTYDFSEMFK-SVAVHVVISSSRRVKLSLDK 200


>UniRef50_UPI0001C41A73 CRISPR-associated protein Cas1-2 n=1 Tax=Methanobrevibacter
           ruminantium M1 RepID=UPI0001C41A73
          Length = 334

 Score = 71.2 bits (173), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 39/258 (15%), Positives = 76/258 (29%), Gaps = 41/258 (15%)

Query: 25  IDVIDGAFVL-IDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT---LLVWVGE 80
           +   D   V+  +   I  ++       ++   G  ++  A+ L A+       + W G 
Sbjct: 12  VAKRDNQIVIKENGKEINYYLAKDISQILLTGKG-SITFDALTLLAENDVDCVSINWKGH 70

Query: 81  AGVRVYASGQP-------------GGARSDKLLYQAKLALDED----------------- 110
              R+ A  +                          +  ++                   
Sbjct: 71  VDYRLSAPDRKNAIVKKEQYFALTDSRSGYLAKAFVRAKIENQKAVLGTLAKSREEKDYI 130

Query: 111 --LRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPK 168
              R KV   + ++       +      + GIEG      ++  A      W    +   
Sbjct: 131 IEQREKVSEHIGKIEKLSNINSDNIRNNILGIEGQASHEYWSAFASVLDEKWEF--FGRS 188

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFD 226
                D +N  ++   + +      +I  AG  P  GF+H+ +    S VYD+ +  +  
Sbjct: 189 GRGAKDPVNSLLNYGYAVIESEIWKSIYLAGLDPYCGFLHSERYGRASLVYDLIEEFRQQ 248

Query: 227 TVVPKAFEIARRNPGEPD 244
            V      I  RN   PD
Sbjct: 249 IVDKTVLSIVNRNQITPD 266


>UniRef50_Q8F1F5 Putative uncharacterized protein n=2 Tax=Leptospira interrogans
           RepID=Q8F1F5_LEPIN
          Length = 550

 Score = 71.2 bits (173), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 52/269 (19%), Positives = 93/269 (34%), Gaps = 50/269 (18%)

Query: 5   PLNPIPLKDRVSMIFL--QYGQIDVIDGAFVL--IDKTGIRTH---IPVGSVACIMLEPG 57
           P+   P K   + + +     +I   D   ++  + +TG ++    IP+  +  + +   
Sbjct: 201 PIRLFPEKREKTTLHVFGHDSRIKKSDNVLLVEKVTETGEKSKSEKIPIQEIESVNIHGN 260

Query: 58  TRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR 117
            ++S   ++        + W    G  +            + + Q K    E +RL + +
Sbjct: 261 CQISSQMIKFLVSEEIPVHWFSGGGNYIGGININPSGVQRR-IRQFKALTKETIRLNLAK 319

Query: 118 KM----------FELRFGE---------------------PAPARRSVEQLRGIEGSRVR 146
           K+          + LR                           +  S  QL GIEGS  R
Sbjct: 320 KLVSAKCESQLRYLLRATRGKDETRNETESYLATIRSGLKNIESADSPSQLLGIEGSSAR 379

Query: 147 ATYALLAKQYG-----VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYA 201
           A ++ L          +  NGR   P      D  N  +S   S LY     AI+A G  
Sbjct: 380 AYFSGLPALLKNSDPFLVPNGRSKRPPK----DPFNATLSFLYSLLYKSVRQAIIAVGLD 435

Query: 202 PAIGFVHTGKPLS--FVYDIADIIKFDTV 228
           P+ GF HT +  +   V D+ ++ +    
Sbjct: 436 PSFGFYHTPRSSAEPLVLDLMELFRVSLC 464


>UniRef50_A5D0Y0 Uncharacterized protein n=40 Tax=cellular organisms
           RepID=A5D0Y0_PELTS
          Length = 344

 Score = 71.2 bits (173), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 55/297 (18%), Positives = 91/297 (30%), Gaps = 47/297 (15%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           G++   D       + G R  IPV     IM+     V+   +   +     L +    G
Sbjct: 25  GELSRKDNTLYFETEEGRRF-IPVEDTGEIMIFGEVDVNKKLLEFLSVKEITLHFFNYHG 83

Query: 83  VRVYAS---GQPGGARSDKLLYQAKLALDEDLRLKVVR--------------KMFELR-- 123
              Y      +         L QA+  LDE+ RL + +              K +  R  
Sbjct: 84  --YYMGSFYPREHLNSGYMTLKQAEHYLDEEKRLVIAKEIVRGAAKNIRQVLKYYYGREK 141

Query: 124 -----------FGEPAPARRSVEQLRGIEGSRVRATYA---LLAKQYGVTWNGRRYDPKD 169
                         P    R    L  +EG+     Y     +       +  R   P  
Sbjct: 142 DVGGKLNAIENLMAPIEECRDTSSLMALEGNIRDHYYRAFDEIVDNPDFAFQERSRRPPK 201

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFV--YDIADIIKFDT 227
               + +N  IS   S +Y +  + I      P IG++H      F    DIA+I K   
Sbjct: 202 ----NYLNTLISFGNSLIYTICLSEIYKTHLDPRIGYLHATNFRRFTLNLDIAEIFKPII 257

Query: 228 VVPKAFEIARRNPGEPDREVR----LACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
           V    F +  +     +   R    +  ++  R    +  L   ++  +   EI  P
Sbjct: 258 VDRLIFTLLGKKMITKEDFDRGTEGIMMKEKARKC-FVENLDEKLKTTINHREIGRP 313


>UniRef50_C9M4Y8 CRISPR-associated protein Cas1 n=1 Tax=Jonquetella anthropi E3_33
           E1 RepID=C9M4Y8_9BACT
          Length = 342

 Score = 70.8 bits (172), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 46/264 (17%), Positives = 81/264 (30%), Gaps = 46/264 (17%)

Query: 18  IFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           ++L Y  GQI     A V+  K       PV  +  I+      ++  A+ L       +
Sbjct: 8   LYLSYDEGQISCSGRALVIRAKDQAPQQFPVHILEQIVCFGSVMLTPDAMNLCLANNVTI 67

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLY-QAKLALDEDLRLKVVRKMFE----------LRF 124
            ++   G R           +  L   Q + A D     ++                LR 
Sbjct: 68  NYLSVYG-RFRGRISGPVRGNVLLRRMQFRRADDPVQTAELATAFLLSKISNARTVLLRH 126

Query: 125 GEPAPAR---------------------RSVEQLRGIEGSRVRATYA-----LLAKQYGV 158
                                         + +LRG+EG      +      +L  +   
Sbjct: 127 ARERETNVFDEAVRDMAGLLVKLKGFTITDLNELRGLEGDAANIYFRCFDSMILKNRETF 186

Query: 159 TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFV 216
           +++GR   P      D IN  +S   S L       + + G  P++GF+H  +P   S  
Sbjct: 187 SFHGRSRRPP----SDPINALLSLGYSLLAAEITGVLESVGLDPSVGFLHKDRPGRPSLA 242

Query: 217 YDIADIIKFDTVVPKAFEIARRNP 240
            D+ +  +   V      +  R  
Sbjct: 243 LDLMEEFRAVVVDRFVLALVNREQ 266


>UniRef50_C5BP90 CRISPR-associated protein Cas1 n=3 Tax=Gammaproteobacteria
           RepID=C5BP90_TERTT
          Length = 339

 Score = 70.8 bits (172), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 50/277 (18%), Positives = 88/277 (31%), Gaps = 45/277 (16%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            I  Q   +       V+  ++     IP+ ++  I       VS   +   A+ G  L 
Sbjct: 9   FITRQKSYVHKQRETIVVEQESEKILQIPIHAIKSIFCFGNVIVSPFLLGFCAENGVGLA 68

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF------------ 124
           +  E G   + +   G    + LL + +    +   L V R +   +             
Sbjct: 69  FFTEYG--RFLARIQGPQSGNVLLRRIQYEKTKSAPLDVARAIIAAKIVSSRSVLQRHIR 126

Query: 125 ---GEPAPARR---------------SVEQLRGIEGSRVRATYALLAK------QYGVTW 160
               +    +                S+++LRG EG      +++           G  +
Sbjct: 127 NYGSQDDVVKVIGRLKHNLEQARVDPSLDRLRGTEGVAAANYFSVFQHLVRVENDAGFAF 186

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYD 218
           NGR   P      D IN  +S   S L     AA+   G  P +GF+HT +    S   D
Sbjct: 187 NGRNKRPP----TDPINAMLSFLYSVLGNDISAALQGVGLDPQVGFLHTDRSGRDSLAMD 242

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIF 255
           + + ++   V         R   +  R+   A     
Sbjct: 243 LLEELRAWWVDRLVLTQVNRREIKA-RDFSQAVSGAV 278


>UniRef50_A4J500 CRISPR-associated protein Cas1 n=1 Tax=Desulfotomaculum reducens
           MI-1 RepID=A4J500_DESRM
          Length = 544

 Score = 70.8 bits (172), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 43/292 (14%), Positives = 92/292 (31%), Gaps = 44/292 (15%)

Query: 17  MIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
           ++++      +       ++         IP+ ++  ++L     +S   ++L    GT 
Sbjct: 214 VLYVDEQGASLYKKGERVLVTKDQIKFKDIPLCNLDQVVLVGNVNLSSQLIKLFLGRGTE 273

Query: 75  LVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------LRF 124
           + ++   G             S   + Q +    ++ RL    +             LR+
Sbjct: 274 VHFISTKGKYYGCLQAALSKNSVLRIAQHRAYQKQEERLLYASEFVRGKLSNMRTNLLRY 333

Query: 125 GEPA-------------------PARRSVEQLRGIEGSRVRATYALLA----KQYGVTWN 161
                                     + + +L G+EG+  R  +++       +    +N
Sbjct: 334 NRSLNNHSIDEAVSRIKNIIKRLEKAKDLNELMGLEGAGSRDYFSVFGLLIKDRVPFDFN 393

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYD 218
            R   P +    D  N  +S + S L      A+   G+ P IGF+H    G+P +   D
Sbjct: 394 KRSRRPPE----DPANALLSFSYSLLLKDVITAVQVVGFDPFIGFLHRSDFGRP-ALALD 448

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
           I +  +             +     + +        F S     K+  L E+
Sbjct: 449 IIEEFRPVVADSVVLTALNKGVIA-EGDFEYRMGGCFLSETGRKKMYRLYEE 499


>UniRef50_Q6L317 DNA polymerase n=2 Tax=Thermoplasmatales RepID=Q6L317_PICTO
          Length = 320

 Score = 70.8 bits (172), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 54/263 (20%), Positives = 95/263 (36%), Gaps = 37/263 (14%)

Query: 15  VSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
            +    Q G+I         + K   R H+PV +V  I++     +S  A+   +++G +
Sbjct: 2   YNFYITQDGEITRDGNTLYFVGKDFKR-HLPVMNVNEIIISAKVSISSWALDYLSKLGIM 60

Query: 75  LVWVGEAGVRVYASGQPGGARSDK---LLYQAKLALDEDLRLKVVRKM------------ 119
           +  +   G   Y S    G R++K   ++ Q +  L++D RL +  +M            
Sbjct: 61  VHILNIYG--NYMSSLIPGNRNEKGNIIIMQVRSYLNDD-RLYIASQMVLGIKHNILRNL 117

Query: 120 --FELR---------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW-NGRRYDP 167
             +                 P   ++  + G EG+     Y+     Y       R + P
Sbjct: 118 RYYNKNNALDDKIEKISGYYPDGNNINSILGTEGNIWSTYYSAFPYIYKKYHEFKREFHP 177

Query: 168 KDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSF--VYDIADIIKF 225
                 D +N  IS   S LY     +I   G  P+I ++H     SF    DI+DI K 
Sbjct: 178 PK----DELNAMISFGNSLLYSNVITSIFLNGLNPSISYLHEPSERSFSLALDISDIFKP 233

Query: 226 DTVVPKAFEIARRNPGEPDREVR 248
             V      +   N  + +   +
Sbjct: 234 VIVERVIANLVNNNIIDSNHFTK 256


>UniRef50_A4FXZ8 CRISPR-associated protein, Cas1 family n=9 Tax=cellular organisms
           RepID=A4FXZ8_METM5
          Length = 342

 Score = 70.8 bits (172), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 42/245 (17%), Positives = 82/245 (33%), Gaps = 49/245 (20%)

Query: 38  TGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSD 97
                 IP   V  I++   + +S  A+ LA +    LV +   G  +            
Sbjct: 40  GENVQEIPAKKVEQILITCPSSISTEAISLAVEENIDLVLLKMNGKPIGRFWHSKHGSIS 99

Query: 98  KLLYQAKLALDEDLRLKVVR--------------KMFELRFGEPAPA------------- 130
            +  +  L  + +L +  V+              KM  +   +                 
Sbjct: 100 TIRKKQLLLSENELGITFVKEWISKKMENQIDFLKMLSMNRRDERRELLKENVLKIDEEI 159

Query: 131 --------RRSVEQLR----GIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTI 176
                    ++++++R    G EG   R  + +++K       +NGR  +P      D  
Sbjct: 160 KKLDNVTFNQNIDEIRNTVQGYEGYASRVYFEMISKSLPEKYQFNGRSRNPAK----DYF 215

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK--FDTVVPKA 232
           N  ++     LY   E + + AG  P IG +H       +F +D+ +  +   D  + K 
Sbjct: 216 NCMLNYGYGILYSQIERSCIIAGLDPYIGILHVDNYNRKAFTFDLIEKYRIYVDKTIFKM 275

Query: 233 FEIAR 237
           F   +
Sbjct: 276 FSTKK 280


>UniRef50_A7NP58 CRISPR-associated protein Cas1 n=6 Tax=Chloroflexi (class)
           RepID=A7NP58_ROSCS
          Length = 338

 Score = 70.4 bits (171), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 50/288 (17%), Positives = 91/288 (31%), Gaps = 58/288 (20%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVGTLLVWVGEAGV 83
           I    G   ++ +    + +P+  +  I++   G  +S   VR  A+ G  + ++  A  
Sbjct: 12  ISKHQGRIRVMKEKERLSEVPIMHLEQILICSDGVGLSSDVVRACAEEGIPIHFLNSANG 71

Query: 84  RVYASGQPGGARSDKLLYQAKLALDEDLR-LKVVRKM-------------FE-------- 121
             Y +    G     L  +A+L   +D R L++ +               +         
Sbjct: 72  GDYGTFVHSGITGMALTRRAQLRAGDDERGLRLAQAFASGKIQSQANMLRYAAKNRKEND 131

Query: 122 -------LRFGEPAPARR-------------SVEQLRGIEGSRVRATYALLAKQY--GVT 159
                  +R                      +   L G EG      +  +A+     + 
Sbjct: 132 PDLHNDLMRTATEILDALPPLRAVRGVLTDETRAALMGFEGMAGARYWTAVARIIPDDLG 191

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVY 217
           W GR          D  NQ ++     L      A++ AG  P  GF+H  +P   S   
Sbjct: 192 WPGRETR----GARDRFNQALNYGYGVLQSQVRTALILAGLDPNAGFLHADRPGKPSLTL 247

Query: 218 DIADIIKFDTVVPKA-------FEIARRNPGEPDREVRLACRDIFRSS 258
           D+ +  +   V           FEI +R+ G  D + R    +     
Sbjct: 248 DLIEEFRQAVVDRTLIGLVNRQFEIVQRDDGLLDEDTRKRIAEKILER 295


>UniRef50_D2LF35 CRISPR-associated protein Cas1 n=1 Tax=Rhodomicrobium vannielii
           ATCC 17100 RepID=D2LF35_RHOVA
          Length = 366

 Score = 70.4 bits (171), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 46/253 (18%), Positives = 76/253 (30%), Gaps = 36/253 (14%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
             + V +   ++          P+  V+ + +    RV+ A +      G  +VW G  G
Sbjct: 50  AVVRVNNSTLLVERPGEPVFERPIELVSTLHIHGWARVTGACIGRLTAQGATVVWRGLHG 109

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM-----FELR-------------- 123
             V  +    GA  D    Q   A  E   L + R +       +R              
Sbjct: 110 YPVALAQPMHGAGLDIRRAQYFEAAGERG-LAIARALISAKIQNMRGLVRRRANIEGRDC 168

Query: 124 -----FGEPAPARRSVEQLRGIEGSRVRATYA----LLAKQYG-VTWNGRRYDPKDWEKG 173
                         S E L GIEGS     ++    + A + G V +  R   P      
Sbjct: 169 LTALAALAKKAKHASRESLLGIEGSATAFYFSAWPHMFAARAGDVEFEVRSRRPPQ---- 224

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPK 231
           + +N  +S A + L      A+ A G  P +G  H  +    S   D+ +  +       
Sbjct: 225 NAVNATLSYAYAVLSAECVCALAAVGLDPRLGVFHQPRSGRASLALDLMEPFRPLIADQA 284

Query: 232 AFEIARRNPGEPD 244
                        
Sbjct: 285 VLTGFNTGQIRTG 297


>UniRef50_Q2SIC8 CRISPR-associated protein Cas1 n=6 Tax=Gammaproteobacteria
           RepID=Q2SIC8_HAHCH
          Length = 338

 Score = 70.4 bits (171), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 49/300 (16%), Positives = 91/300 (30%), Gaps = 56/300 (18%)

Query: 11  LKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K   + +++      +       V+          P  +VA I       VS   +   
Sbjct: 1   MKKLQNSLYVTRQESYLHKERETIVIKQGKDKLAQFPAHAVANIFCFGQISVSPFLMGYC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDL-RLKVVRKMF------E 121
            + G  LV+  E G +  A  Q   + +  L  +     D+D  RL + R +        
Sbjct: 61  GEQGIGLVFFTEYG-KFLARIQGRQSGNVLLRREQYRVSDKDTPRLDIARSIVLAKIANS 119

Query: 122 LRFGEPAPARR------------------------SVEQLRGIEGSRVRATY---ALLAK 154
            R  +     +                        +++ LRG+EG      +     L K
Sbjct: 120 RRVLQREVRNKGAHPSLDEAIARLANCLRRCERPDNLDILRGLEGEAAAIYFGVFNQLLK 179

Query: 155 QYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL- 213
           Q G  + GR   P      D +N  +S   + +     +A+   G  P +G++H  +P  
Sbjct: 180 QDGFDFKGRVRRPP----TDPVNALLSFLYTLVAQEISSALQGVGLDPYVGYLHVDRPGR 235

Query: 214 -SFVYDIADIIKFDTVVPKA-------------FEIARRNPGEPDREVRLACRDIFRSSK 259
                DI +  +                     F+I          + R      ++  K
Sbjct: 236 VGLALDILEEFRAWWCDRLVLTLINRKEVKASDFDIEASGAVRLKEDARRKVLVAYQEKK 295


>UniRef50_Q74H36 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Geobacter
           sulfurreducens RepID=Q74H36_GEOSL
          Length = 559

 Score = 70.4 bits (171), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 51/293 (17%), Positives = 93/293 (31%), Gaps = 55/293 (18%)

Query: 5   PLNPIPLKDRVSMIFLQYGQID-VIDGAFVLIDKTGIRTHIPVGSVA----CIMLEPGTR 59
           P   IP   R   +++Q  +     DG  ++I++   R  +    +       +    T 
Sbjct: 211 PRPIIPADGRGLPLYVQSPKAYVRKDGDCLVIEEE--RVRVAEARLGETSQVALFGNAT- 267

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRK- 118
           ++ AA+    +    + W+   G  +  +   G    +   YQ + + D +  L + R+ 
Sbjct: 268 LTTAALHECLRREIPVTWLSYGGWFMGHTVSTGHRNVETRTYQYQRSFDPETCLNLARRW 327

Query: 119 -----------MFELRFGEPAPARR-------------------SVEQLRGIEGSRVRAT 148
                      +     GE   A+                    S+E L GIEG+     
Sbjct: 328 IVAKIANCRTLLRRNWRGEGDEAKAPPGLLMSLQDDMRHAMRAPSLEVLLGIEGASAGRY 387

Query: 149 YALLAKQY--------GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGY 200
           +   ++          G  +  R   P      D +N  +S A + L      A+ A G 
Sbjct: 388 FQHFSRMLRGGDGEGMGFDFTTRNRRPPK----DPVNALLSFAYAMLTREWTVALAAVGL 443

Query: 201 APAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
            P  GF H    G+P +   D+ +  +                      VR A
Sbjct: 444 DPYRGFYHQPRFGRP-ALALDMMEPFRPLIADSTVLMAINNGEIRTGDFVRSA 495


>UniRef50_Q9YCL8 Putative CRISPR-associated protein Cas1 n=1 Tax=Aeropyrum pernix
           RepID=Q9YCL8_AERPE
          Length = 327

 Score = 70.0 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 30/154 (19%), Positives = 54/154 (35%), Gaps = 15/154 (9%)

Query: 122 LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTINQC 179
           LR  +        ++L  IE    R  +  +A+     + ++GR     D    D  N  
Sbjct: 144 LRIADEDGPGF-RDKLLSIEARASRRYWQCIAEILPGRLGFSGR-----DRGALDPFNAA 197

Query: 180 ISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVP-KAFEI- 235
           ++     LY + E ++L  G  P +G  H+ K    S   D  +  +   V    A +  
Sbjct: 198 LNYGYGMLYSIVEKSLLLVGLDPYLGVFHSEKSGKPSLTLDAIEPFRAPIVDRILALKAG 257

Query: 236 ---ARRNPGEPDREVRLACRDIFRSSKTLAKLIP 266
               +   G  D + R        SS ++   + 
Sbjct: 258 RMYLKLEAGRLDYKSRKEVAKAVASSLSMKAAVR 291


>UniRef50_A5ILM3 CRISPR-associated protein, Cas1 family n=3 Tax=Bacteria
           RepID=A5ILM3_THEP1
          Length = 327

 Score = 70.0 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 48/291 (16%), Positives = 93/291 (31%), Gaps = 44/291 (15%)

Query: 16  SMIFLQYGQIDVIDGAFV--LIDKTGIRTH--IPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +      G+I   + + +    D+ G +    IPV +V  I       ++   +  AA+ 
Sbjct: 4   NYYVFSSGRIRRRENSILIEYQDRDGKQQKRFIPVENVDQIFFLGEVDLNSKFLDFAAKN 63

Query: 72  GTLLVWVGEAGVRVYAS---GQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------- 119
             +L +    G   Y      +      + L+ Q +  LD + RL + RK          
Sbjct: 64  NIVLHFFNYYG--YYTGSFYPREKFLSGELLVRQVEHYLDNEKRLSLARKFVEGAIHNFK 121

Query: 120 ----------------FELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGR 163
                           ++ R         ++ +L   E    +  Y+         +  R
Sbjct: 122 RNIEKRGFDIVSKISEYQER----IKHVATIPELMSCEAHARKLYYSTWEDITDWPFEER 177

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIAD 221
              P   E    +N  IS   S  Y V    +      P + ++H    K  S   DI++
Sbjct: 178 SMQPPLNE----LNALISFGNSLTYSVVLKELYHTHLNPTVSYLHEPGTKRFSLALDISE 233

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
           I K   V    F++      + +         +F + +     +   E++L
Sbjct: 234 IFKPIFVDRIIFKLINLGKIKRENHFLQESNGVFLNDEGRRIFVEEFENML 284


>UniRef50_C9LM09 CRISPR-associated protein Cas1 n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LM09_9FIRM
          Length = 331

 Score = 70.0 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 45/271 (16%), Positives = 92/271 (33%), Gaps = 43/271 (15%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S I++     +++   G +V+  +      +P   V  + L    ++S + +    +  
Sbjct: 1   MSWIYVTEPGAKLNRQGGRYVISRENETICEVPSAVVEGVTLFDSIQISSSVIVDFLERN 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAK---LALDEDLRLKVVRKM---------- 119
             L W+   G R +  G+        +L Q +      D+D  L + +++          
Sbjct: 61  IPLTWISSTG-RFF--GRLESTDHQNVLRQKEQFDALADKDFCLALAKRVVFGKVYNQRT 117

Query: 120 ----FELRFGEPAPARR---------------SVEQLRGIEGSRVRATYALLAKQYGVTW 160
               +  R  +P   +                SVE++ G EG   R  +  +       +
Sbjct: 118 ILRNYNRRAEDPFIEKVRSDIRILADKLHMAHSVEEVMGYEGMMARIYFQAIGHILPEEF 177

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVY 217
              +   +     D  N  +S   + L     +AI+  G  P IGF+H    G P +   
Sbjct: 178 RFEKRTKRPPR--DYFNSLLSFGYTLLMYDFYSAIVNCGLHPYIGFLHALRNGHP-ALAS 234

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVR 248
           D+ +  +   V      +        D  V+
Sbjct: 235 DLMEPWRPAVVDAFCLSLVTHREISKDYFVK 265


>UniRef50_D1N0J7 CRISPR-associated protein Cas1 n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N0J7_9BACT
          Length = 347

 Score = 70.0 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 52/304 (17%), Positives = 92/304 (30%), Gaps = 63/304 (20%)

Query: 18  IFLQY-GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV------SHAAVRLAAQ 70
           ++L   G++   D            T  P      +       V      S  AV +  +
Sbjct: 3   LYLTRSGRLRRRDNTLRFERVNLPETEDPEVEAEALEEGKADAVQALPVESIDAVYVFGE 62

Query: 71  --VGTLLV--------------WVGEA-GVRVYASGQPGGARSDKLLYQAKLALDEDLRL 113
             V T L+              W G   G  +           D ++ Q +   + + RL
Sbjct: 63  LSVNTKLINFLNCKKVPVHFFNWYGHHTGTLL---PHAEQLSGDLVIRQGEAYRNPEERL 119

Query: 114 KVVR--------------KMFELRFGEPAPARRSVEQL-------------RGIEGSRVR 146
            + R              + ++ R G    +  +V++L              G+EG+  +
Sbjct: 120 MICRNLLEAVFHNILSVLQYYQRRKGGLEKSIAAVKELEQKLAEQDTPEGLMGLEGNVRK 179

Query: 147 ATYALLAKQYGVTW--NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAI 204
             Y       G T     R Y P D    + +N  IS   S LY    + +      P I
Sbjct: 180 LYYQSWPVWLGKTAEHFKRVYHPPD----NPLNALISFLNSLLYTACVSELYRTALYPGI 235

Query: 205 GFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLA 262
            ++HT +    S   D+ +  K   V    F +        DR+ R        +     
Sbjct: 236 SYLHTPQTRRFSLALDLVEPFKPLLVDRMIFRLLDSRAIG-DRDFRKHSNGFLLTDDARR 294

Query: 263 KLIP 266
           +++ 
Sbjct: 295 RILQ 298


>UniRef50_A7HNI6 CRISPR-associated protein Cas1 n=1 Tax=Fervidobacterium nodosum
           Rt17-B1 RepID=A7HNI6_FERNB
          Length = 334

 Score = 70.0 bits (170), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 48/298 (16%), Positives = 103/298 (34%), Gaps = 47/298 (15%)

Query: 15  VSMIFLQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
           +++  L+ G  +   DG  ++     +   IP+  +  I L     ++   +        
Sbjct: 1   MTIYVLEQGTVLAKKDGRMIITKAKQVLDEIPLKKIERINLLGNITLTSQMINYCLDNKI 60

Query: 74  LLVWVGEAGV---RVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE--------- 121
            ++++ + G    ++Y             L Q + A D+  +L++ + + +         
Sbjct: 61  EVIFMTQHGRYRGKLYT---DEYRNVLLRLKQYERATDKQFQLEISKSIVQGKLQNYYNF 117

Query: 122 -----LRFG---------------EPAPARRSVEQLRGIEGSRVRATYALLAKQYG---V 158
                                   E     ++V+++RG EG   +  ++   K      +
Sbjct: 118 LTQKSKNLPKGLLSEERAGIRTVIEKVNKAKTVDEVRGYEGIGSKIYFSGFKKCIRTEEL 177

Query: 159 TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFV 216
           T+NGR   P      D IN  +S     LY     AI A G  P  G +HT      S +
Sbjct: 178 TFNGRTAHPPK----DEINAMLSLGYYFLYVEMLLAINAVGLDPYFGNLHTIDVSKQSLL 233

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFR-SSKTLAKLIPLIEDVLA 273
           +D+ +  +   +      +      + + +      DI+  +   + K I   E ++ 
Sbjct: 234 FDLVEEFRCVIIDNFVLNLINLKTIKKE-DFEKRENDIYYFTKDGMKKYITEYEQMMK 290


>UniRef50_B8GSH8 CRISPR-associated protein Cas1 n=1 Tax=Thioalkalivibrio sp.
           HL-EbGR7 RepID=B8GSH8_THISH
          Length = 691

 Score = 69.6 bits (169), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 44/287 (15%), Positives = 85/287 (29%), Gaps = 38/287 (13%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSV-ACIMLEPGTRVSHAAVRLAAQVGTLLVWVG 79
           +  ++ +  G   +          P+ ++    +L P    +     L  +   L +  G
Sbjct: 371 EPARVGLDGGRLRVQRGEAELLSAPLETLAGVTLLGPHQVSTQLLGALLDRGIPLALATG 430

Query: 80  EAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP--------- 129
           +  +R     G PG A     + QA    D+   L+  R + + R  +            
Sbjct: 431 QGRLRGVLWNGVPGDAGPGLWMRQAACFEDDARALEAARAVVDARLRQQREVLRNRMSPE 490

Query: 130 -----------------ARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDW 170
                            A      L G+EG   R  +  LA+     + + GR   P   
Sbjct: 491 RCDDLLPRLDRLIAKTAAASDRASLNGLEGQAARLYFGALAELLPPELGFTGRNRRPPR- 549

Query: 171 EKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTV 228
              D  N  +S   + L+   +  +   G  P  GF H    L  +   D+ +  +   V
Sbjct: 550 ---DPFNVLLSLGYTVLHAHVDTVVRLNGLYPWRGFYHQPHGLHPALASDLMEPFR-HLV 605

Query: 229 VPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
              A  +  R       +           +    + +  + + L   
Sbjct: 606 ERVALNVVARGRIRV-SDFAQQGDACRIEAGARRRYLADLSERLLTP 651


>UniRef50_UPI000197AF65 hypothetical protein BACCOPRO_02409 n=1 Tax=Bacteroides coprophilus
           DSM 18228 RepID=UPI000197AF65
          Length = 340

 Score = 69.6 bits (169), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 45/274 (16%), Positives = 91/274 (33%), Gaps = 57/274 (20%)

Query: 11  LKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSV-ACIMLE-----PGTRVSH 62
           ++  ++ +++      I       V+         IP  ++ + +        PG     
Sbjct: 1   MRKLLNTLYVTTPNAYISKDGLNIVVSVNQEEVFRIPAINIESIVTFGYMGASPG----- 55

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLY-QAKLALDEDLRLKVVRKM-- 119
             ++L +  G  L ++   G +  +  Q     +  L   Q +L  DE   L V   M  
Sbjct: 56  -VMKLCSDSGISLTFLSPHG-KFISRVQSATKGNVLLRKKQYQLVDDEAWSLHVSLLMIG 113

Query: 120 ------------FELRFGEPAPARRSVEQLR----------------GIEGSRVRATYAL 151
                       +   +GE     ++++ L                 G EG    A + +
Sbjct: 114 GKIQNYRNILRRYIRDYGENENVNQAIQTLERAKRNALQAPDKTTLIGYEGLASNAYFEV 173

Query: 152 L-----AKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGF 206
           L      ++    + GR   P      D +N  +S A + +     AA+   G  P +GF
Sbjct: 174 LPVLILNQKADFPFQGRNRRPPK----DAVNAMLSFAYTLIANDVAAALETIGLDPYVGF 229

Query: 207 VHTGKPL--SFVYDIADIIKFDTVVPKAFEIARR 238
           +HT +P   S   D+ + ++          +  +
Sbjct: 230 LHTLRPGRTSLALDMMEELRAYLGDRFVLSLINK 263


>UniRef50_A3MVN2 CRISPR-associated protein, Cas1 family n=4 Tax=Thermoproteaceae
           RepID=A3MVN2_PYRCJ
          Length = 294

 Score = 69.3 bits (168), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 49/273 (17%), Positives = 84/273 (30%), Gaps = 47/273 (17%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVA-CIMLEPGTRVSHAAVRLAAQVGTLLVWVGE 80
           YG         +++++ G R   P+  V    +L  G  ++  A+R   + G ++    +
Sbjct: 8   YGTRIRTRKGLLVVERGGERREYPLHQVDEVFILTGGVSITSRALRALLRAGAVVAVFDQ 67

Query: 81  AGVRV------------------YASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
            G  +                  YA+   GG                  +L+ V+  +  
Sbjct: 68  RGEPLGIFMRPVGDATGEKRRCQYAAA-AGGRGLQWAREWV--WKKMRGQLQNVKA-WRR 123

Query: 123 RFGE-------------PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD 169
           R                   A  S  ++   E +   A +    +  G    GR     D
Sbjct: 124 RLAHYGDYVEQIGRALEALRAAASPGEVMEAEAAAAEAYWRAYGEVTGFP--GR-----D 176

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDT 227
            E GD +N  ++     L  +   +IL AG  P +GF+H  K    S V D  +  +   
Sbjct: 177 QEGGDPVNAALNYGYGVLKALCFKSILLAGLDPYVGFLHVDKSGRPSLVLDFMEQWRPRV 236

Query: 228 VVPKAFEI--ARRNPGEPDREVRLACRDIFRSS 258
               A          G  D + RL         
Sbjct: 237 DAVVAKVAGELATENGLLDHKSRLRVAAAVLEE 269


>UniRef50_B0K547 CRISPR-associated protein Cas1 n=12 Tax=Bacteria RepID=B0K547_THEPX
          Length = 330

 Score = 69.3 bits (168), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 48/254 (18%), Positives = 84/254 (33%), Gaps = 44/254 (17%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           G++   D      +    R  IPV + + IM+     ++   +    Q   +L +    G
Sbjct: 11  GELKRKDNTL-FFEGENGRKFIPVENTSEIMVFGEVSLNKRLLEFLTQSEIILHFFNHYG 69

Query: 83  VRVYAS---GQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------------FELR-- 123
              Y      +        +L QA+   D   RL + +K               +  R  
Sbjct: 70  --YYVGSYYPREHLNSGYMILRQAEHYNDGSKRLYLAQKFVEGAYKNIRQVLKYYSNRGK 127

Query: 124 -----------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQY----GVTWNGRRYDPK 168
                       GE   +  ++ +L  IEG+ +R  Y     +        ++ R   P 
Sbjct: 128 DLEDVIYSIEKLGESVDSTSTINELMAIEGN-IREYYYKAFDEIIQNPDFKFDFRSKRPP 186

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFD 226
                + +N  IS   S +Y  T + I      P IGF+H       S   D+++I K  
Sbjct: 187 Q----NFLNTLISFGNSLMYTTTLSEIYKTHLDPRIGFLHATNFRRFSLNLDVSEIFKPI 242

Query: 227 TVVPKAFEIARRNP 240
            V    F +  +  
Sbjct: 243 IVDRTIFTLLSKKM 256


>UniRef50_Q8YZS6 Alr0381 protein n=6 Tax=Cyanobacteria RepID=Q8YZS6_ANASP
          Length = 374

 Score = 68.9 bits (167), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 46/269 (17%), Positives = 89/269 (33%), Gaps = 45/269 (16%)

Query: 18  IFL-QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
           ++L + G I       ++I K     +  +  +  I++ PG +++   +      G   +
Sbjct: 42  LYLTEPGTILRYRNESLIIMKQEKSHNCRLAEITLIVVLPGVQLTDVVISQLLDRGIETI 101

Query: 77  WVGEAG-VRVYASGQPGGARSDKL----------------------LYQAKLALDEDLR- 112
           ++ + G  R    G      + +L                      +   ++ L    R 
Sbjct: 102 FLRQDGQFRGRLQGHFATNMTIRLAQYRTVETTFGMALAQKLVIGKVRNQRVLLQRRNRA 161

Query: 113 -------LKVVRKM---FELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWN- 161
                  L     +   +  +         +  +L G+EG   R  Y  L   +   WN 
Sbjct: 162 TNGQISELTEAIDLISVYASQLNNTTTP-LNRNELMGVEGICARTYYQALKHWFPTQWNF 220

Query: 162 -GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYD 218
            GR   P      D IN  +S     L     +A + AG  P +GF H  +P   + V D
Sbjct: 221 NGRNRRPP----LDPINALLSWGYGVLLARVFSACVQAGLDPYLGFFHAIEPYRPNLVLD 276

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREV 247
           + +  +   VV +A     ++      + 
Sbjct: 277 LMEEFRP-VVVDQAVISLIQSDLLTQEDF 304


>UniRef50_B2SPB2 Crispr-associated protein Cas1 n=56 Tax=Bacteria RepID=B2SPB2_XANOP
          Length = 344

 Score = 68.5 bits (166), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 44/265 (16%), Positives = 85/265 (32%), Gaps = 48/265 (18%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           +       V+  +   R  +PV  +  ++      VS   +   ++ G  + ++   G R
Sbjct: 17  LRKDGANIVMEVERQERARLPVHMLESLVCIGRVAVSPQLLGFCSEHGISICYLTPQG-R 75

Query: 85  VYASGQPGGARSDKLLYQ------------------------------AKLALDEDLRLK 114
             A  +   + +  L                                 A+   D    L 
Sbjct: 76  FLARVEGPVSGNVLLRRAQYRRSDDPAGCAAIVRHLLAGKIHNQRAVLARGWRDHGDCLT 135

Query: 115 VVRKMFE-----LRFGEPAPARRSVEQLRGIEGSRVRATYALL-----AKQYGVTWNGRR 164
            V           R  +       V+ LRG+EG   ++ + +      A +  + + GR 
Sbjct: 136 DVAAFQHSLKRLKRIPQRVLVETDVDVLRGLEGEAAQSYFGVFGQLVRADKPLLRFGGRN 195

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADI 222
             P      D  N  +S   + L     +A+ + G  PA+GF+H  +P   S   D+A+ 
Sbjct: 196 RRPPR----DAFNALLSFLYTLLTHDCRSALESVGLDPAVGFLHRDRPGRPSLALDLAEE 251

Query: 223 IKFDTVVPKAFEIARRNPGEPDREV 247
            +       A  +  R     +R+ 
Sbjct: 252 FRPLLGERLALSLINRRQLN-ERDF 275


>UniRef50_A1WUP2 CRISPR-associated protein Cas1 n=1 Tax=Halorhodospira halophila SL1
           RepID=A1WUP2_HALHL
          Length = 320

 Score = 68.5 bits (166), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 46/249 (18%), Positives = 89/249 (35%), Gaps = 43/249 (17%)

Query: 18  IFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++     ++++   A  + +       +P+  +  +++     +S   +   A+ G  L
Sbjct: 4   LYIDRRRTRLELAHKALTIREPEAQPRSVPLSLIDRLIVIGQVELSSGVLTTLAESGVSL 63

Query: 76  VWVGEAGVRVYASGQP-GGARSDKLLYQAKLALDEDLRLKVVRKMFELRF---------- 124
           V++   G R  A  +  G   + + L Q +L   E  R    R++  LR           
Sbjct: 64  VFMPSRGQRRSAFLRSEGHGDAVRRLGQYRLIHLEAERQAWARRLVRLRLAGQQRLLASA 123

Query: 125 ----GEPAPARRSV------------------EQLRGIEGSRVRATYALLAKQYG--VTW 160
                +      +                   EQLRG EG+   A +      +   + +
Sbjct: 124 LYRRPDQRQPLTAAHREIEAAQATVRREAPAGEQLRGQEGTAAAAFFRGYGALFAEALGF 183

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYD 218
           +GR   P      D +N  +S   +  +G    A+ AAG  PAIG +H       S   D
Sbjct: 184 SGRNRRPPR----DPVNAVLSLGYTLAHGDALRAVTAAGLDPAIGVLHEPAWGRDSLACD 239

Query: 219 IADIIKFDT 227
           + +I +   
Sbjct: 240 LTEIARARV 248


>UniRef50_Q2LQX3 Uncharacterized protein predicted to be involved in DNA repair n=1
           Tax=Syntrophus aciditrophicus SB RepID=Q2LQX3_SYNAS
          Length = 386

 Score = 68.1 bits (165), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 39/252 (15%), Positives = 76/252 (30%), Gaps = 37/252 (14%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            +  Q  +I       ++     +   +    +  +++     ++H A+    + G  +V
Sbjct: 4   YVRTQGARIIKEGRHLLVRKGDAVYHTLFTYKLDQLVIFGNVEITHQALAQLMRYGIDVV 63

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------LRF-- 124
           ++   G  +     P          Q  L  +E   L+ VR +            +R   
Sbjct: 64  FLSFRGRYLGRISPPESKNVFLHKRQYSLLGNETFTLRQVRAIVAGKLANMATLLMRIKR 123

Query: 125 ----------GEPAPA-------RRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRY 165
                          +         SV+ LRG EG      +    + +     +  R  
Sbjct: 124 SRNVSLASQKAHEIQSLIRLLFQAESVDSLRGYEGRGSALYFEAFGRGFIENQGFFRRVR 183

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADII 223
            P      D +N  +S   + L     AA+  AG  P  GF+H       S V D+ +  
Sbjct: 184 RPP----TDPVNSVLSLLYTFLMNRVYAAVRVAGLDPYPGFLHALDYGRYSLVLDLMEEF 239

Query: 224 KFDTVVPKAFEI 235
           +          +
Sbjct: 240 RTIIADTLTLSL 251


>UniRef50_Q6L363 DNA polymerase n=1 Tax=Picrophilus torridus RepID=Q6L363_PICTO
          Length = 318

 Score = 68.1 bits (165), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 41/245 (16%), Positives = 91/245 (37%), Gaps = 28/245 (11%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +   +  G ++    +    +    +  IP+ ++  I++     ++  A+ + ++    +
Sbjct: 3   TYYIISSGTLNREMDSLRFSNSNENKI-IPLENIESIIISGNVSITKPAISILSKKNIPV 61

Query: 76  VWVGEAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVR--------------- 117
            ++       Y S             ++ QA  A + D R+K+ R               
Sbjct: 62  FFMSMYD--NYISSLIPEDYLLSGKVIMNQAIKAYNIDERIKIARIFVYAAARNMAIVLK 119

Query: 118 --KMFELRFG-EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGD 174
              M +++   +     +S+ +L   EG+  R  +  +  QY +  N +          +
Sbjct: 120 RGNMGKIKIPYKEIMESKSINELMSYEGN-FRNNFLNIVDQY-LPNNYKIIKRSRRPPRN 177

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPKA 232
            +N  IS     LY +TE+ I      PAI F+H    +  S   D+++I K       A
Sbjct: 178 KMNALISYLNMLLYSITESQIFLTHLNPAISFLHEPFERRNSLSLDVSEIFKPLICDRLA 237

Query: 233 FEIAR 237
            ++ +
Sbjct: 238 IKMVK 242


>UniRef50_B6IX22 CRISPR-associated protein Cas1, putative n=2 Tax=Rhodospirillum
           RepID=B6IX22_RHOCS
          Length = 350

 Score = 67.7 bits (164), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 46/241 (19%), Positives = 75/241 (31%), Gaps = 38/241 (15%)

Query: 45  PVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAK 104
           P      ++L   T ++  A+RL       +  +   G        P    +D  L+Q  
Sbjct: 48  PHRLETLVLLGQ-TALTPNAMRLCMAHRITVALLDGGGNLAARVVPPEARTADLRLHQYT 106

Query: 105 LALDEDLRL------------KVVRKMFELRFGEPAPA-----------------RRSVE 135
           L    + RL                 +  +R  +  P                    + E
Sbjct: 107 LHHTPEERLIRARGVVAAKLHNAAEVLRAVRSNQSNPDIARAIAEVERTAATVADAVTPE 166

Query: 136 QLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEA 193
            L GIEG+  R  +A L   +   + + GR   P      D  N  +S     L      
Sbjct: 167 TLLGIEGNGARQYFAGLRAAFVGDIRFTGRAQRPP----PDPANSMLSFGYVLLGNRIAG 222

Query: 194 AILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLAC 251
            + A G  P +GF H  +P   S   D+ + ++   V      +      +PD     A 
Sbjct: 223 LLEARGIDPCLGFFHALRPGRPSLALDLLEELRQPVVDRLVLRLCNLRMLKPDMFEADAE 282

Query: 252 R 252
           R
Sbjct: 283 R 283


>UniRef50_D0KYZ2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria RepID=D0KYZ2_HALNC
          Length = 344

 Score = 67.7 bits (164), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 48/261 (18%), Positives = 88/261 (33%), Gaps = 49/261 (18%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           + + +    +  +   +  +P+  +  ++      +S A +   A  G  LV +  +G  
Sbjct: 17  VHLENATVRIDVEREKKLQVPLHHLNGLVCFGNIMISPALMHRLADDGKSLVLMDSSG-- 74

Query: 85  VYASGQPGGARSDKLLYQA--KLALDEDLRLKVVRKMFELRFGE---------------- 126
            + +   G    + LL QA  + A D    L++ R +   +                   
Sbjct: 75  RFKARLEGPVSGNILLRQAHHRQASDAAFALEIARTIVSGKLKNSRSVVQRGARETSDTI 134

Query: 127 -----------------PAPARRSVEQLRGIEGSRVRATYALL------AKQYGVTWNGR 163
                             A A  S+++LRGIEG   R  ++ +      A +     NGR
Sbjct: 135 ETTQLTRSADNLAASLRAAAAATSMDELRGIEGEAARGYFSAINLIVKTAMRANFQLNGR 194

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIAD 221
              P      D  N  IS   + L     +AI A G    +GF+H  +P   +   D+ +
Sbjct: 195 TRRPP----LDRFNALISFLYAMLMNDCRSAIEATGLDAQLGFLHAVRPGRAALALDLME 250

Query: 222 IIKFDTVVPKAFEIARRNPGE 242
             +       A  +  R    
Sbjct: 251 EFRAIAADRLALTLINRGQIN 271


>UniRef50_Q7MRD4 Putative uncharacterized protein n=1 Tax=Wolinella succinogenes
           RepID=Q7MRD4_WOLSU
          Length = 314

 Score = 67.7 bits (164), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 67/275 (24%), Positives = 106/275 (38%), Gaps = 23/275 (8%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLE-PGTRVSHAAVRLAAQVGTLLVWVGEA 81
             + V D   V+  + G RT +P+  +  +++E P   +S A +   AQ GT L+    +
Sbjct: 13  CHLRVRDRQLVIESREGERTQLPLADIGVVIVENPQVTLSAALLSALAQEGTALMSCDSS 72

Query: 82  GVR--VYASGQPGGARSDKLLYQAKLALDEDL--------RLKVVRKMFELRFGEPAPAR 131
            +   V+A        +     QA +  +           R KV  +   LR      A 
Sbjct: 73  HLPDGVFAPFGTHSRHTRAARVQA-VWSEPFKKRCWQKIVRAKVSSQAEVLRRVGAEDAA 131

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKG-DTINQCISAATSCLYGV 190
           R +E L G   S    T  + A+   V W     + K W+ G D  N  ++   + L G 
Sbjct: 132 RRLENLVGKVTSG--DTTGVEAQAAQVYWRSLFVNFKRWDGGLDARNGGLNYGYAVLRGA 189

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKF--DTVVPKAFEIARRNPGEPDRE 246
              AI  AG  PA G  H G+  SF    D+ +  +   D +V   F + R       RE
Sbjct: 190 LGRAIAGAGLIPAFGLHHAGELNSFNLADDLIEPFRPFVDLLVWGLF-LERTGDDPLTRE 248

Query: 247 VRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPA 281
            R+    I   S  +       E +L+A +I   +
Sbjct: 249 ERMRIAQILGESCIMT---ERYETLLSATQIIARS 280


>UniRef50_C0BZ41 Putative uncharacterized protein n=3 Tax=Clostridiales
           RepID=C0BZ41_9CLOT
          Length = 343

 Score = 67.3 bits (163), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 44/271 (16%), Positives = 95/271 (35%), Gaps = 48/271 (17%)

Query: 11  LKDRVSMIFLQYGQ--IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K  ++ +++      + +     V+++       +P+ ++  I+    T  S A +   
Sbjct: 1   MKKLLNTLYVTSTNRYLFLDGENVVILEDQEEIGRVPLHNLEGIVTFGYTGASPALMGAC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGA-RSDKLLYQAKLALDEDLRLKVVRKM-------- 119
           A+    L ++   G R  A               Q +++  +   +K+ R          
Sbjct: 61  AERNIDLSFMSGNG-RFLARVSGEVRGNVTLRKEQYRISEQKKESIKIARNFITGKVYNA 119

Query: 120 ----------FELRFGEPAPARRSV---------------EQLRGIEGSRVRATYAL--- 151
                     + LR        +S                E+L GIEG      +++   
Sbjct: 120 KWVLERAARDYPLRLDVDRIKEKSAFMSGNLPKIRECEDAERLLGIEGESASLYFSVFDE 179

Query: 152 --LAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
             L ++   ++ GR   P      D +N  +S A + L G+  +A+ + G  P +GF HT
Sbjct: 180 LILQQKDEFSFGGRNKRPP----LDNVNAMLSFAYTLLTGMCASALESVGLDPYVGFYHT 235

Query: 210 GKPL--SFVYDIADIIKFDTVVPKAFEIARR 238
            +P   S   D+ + ++          +  +
Sbjct: 236 DRPGRVSLALDLMEELRSVMADRFVLTLINK 266


>UniRef50_C0FSR1 Putative uncharacterized protein n=1 Tax=Roseburia inulinivorans
           DSM 16841 RepID=C0FSR1_9FIRM
          Length = 359

 Score = 67.3 bits (163), Expect = 6e-10,   Method: Composition-based stats.
 Identities = 52/295 (17%), Positives = 97/295 (32%), Gaps = 44/295 (14%)

Query: 15  VSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
            +   +  G +   D   +   + G +  IPV +   + +     +S        QVG  
Sbjct: 32  HNYHLINEGILTKQDFNILFESENGKKY-IPVETTDSLYIYSNVIMSGNFFDFMNQVGLN 90

Query: 75  LVWVGEAGVRVYASGQPGGARS-DKLLYQAKLALDEDLRLKVVRKM-------------- 119
           + ++ + G ++ +       R+    L Q ++   E  RL + R++              
Sbjct: 91  VSFINKYGEKIGSFVPNNSRRNIKTELKQLRMYDSEKERLDMARRLEIASVSNIRANLRY 150

Query: 120 FELR---------------FGEPAPARRSVEQLRGIEGSRVRATYA-----LLAKQYGVT 159
           ++ R                       R +  +  +E    +  Y      L  KQ+   
Sbjct: 151 YQRRKNATELGAAVKDMTDIITKLNEARDINHMMMLEAQARQKYYGCFNSILEGKQFY-- 208

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVY 217
           ++ R   P      D +N  IS   + LY      I        IG VH    +P S   
Sbjct: 209 FDKRTRRPPQ----DPLNAMISFGNTLLYQRIANEINRTSLDIRIGIVHAAGNRPESLNL 264

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
           D+AD+ K   V    F +  R     +  V +    I+ +++     I   E+ L
Sbjct: 265 DLADLFKPILVDRTIFTLVNRKMINVNDFVEVENNGIYLNNRAKKIFISEYENKL 319


>UniRef50_C9LGP6 CRISPR-associated protein Cas1 n=3 Tax=Prevotella
           RepID=C9LGP6_9BACT
          Length = 295

 Score = 67.3 bits (163), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 40/267 (14%), Positives = 99/267 (37%), Gaps = 26/267 (9%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKT--GIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVG 72
           S++F+    + + +G  V+I K        +P+  +  +M+      ++   +    +  
Sbjct: 5   SLVFMHPATLSLRNGQMVIIRKEIPDDNLIVPIEDIGLVMINHAMVSLTIPLLNALTEQN 64

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRK-MFELRFGEPAPAR 131
             +++  E G+    +      + +    Q +   ++    +V++K +++         +
Sbjct: 65  VAVIFCNEKGMP---ASMLYNLQGNTT--QGETLHNQLEAGEVLKKTLWKQIIEAKIKNQ 119

Query: 132 RSVEQLRGIEGSRVRATYALL------------AKQYGVTWNGRRYDPKDWEKGDTINQC 179
            ++    G EGS ++  Y  +            A+ Y     GR +       G  IN  
Sbjct: 120 AALLNKMGKEGSILKPLYTNVKSGDSDNREGIAARLYWTALFGRDFIRDRNIPG--INSL 177

Query: 180 ISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIAR 237
           ++   S L      A++++G  PA+G  H  +  +F    D+ +  +   V    FE+  
Sbjct: 178 LNYGYSVLRAAVTRALVSSGLFPALGIFHHHRSNAFPLSDDLMEPFRP-FVDEIVFELTA 236

Query: 238 RNPGEPDREVRLACRDIFRSSKTLAKL 264
           +   E +   +     +       +K+
Sbjct: 237 QGEAELNTATKSRLIRVLYVDTYFSKI 263


>UniRef50_C7RP03 CRISPR-associated protein Cas1 n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RP03_9PROT
          Length = 339

 Score = 67.3 bits (163), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 58/329 (17%), Positives = 117/329 (35%), Gaps = 62/329 (18%)

Query: 18  IFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++      +     A V  +       +P+  ++ + +     +S A +    + G  +
Sbjct: 4   LYVDRRGVTLKADGEALVFYENGERIGTVPLAPLSRVFMRGDVTLSSALLGKLGERGIGV 63

Query: 76  V-WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG--------- 125
           V   G   V     G+P    + + + Q +L+LD D  L+  R + E +           
Sbjct: 64  VVLSGRKAVPTMLLGRP-HNDAARRVAQYRLSLDGDFCLRFARAIVEAKLRAQATFLTER 122

Query: 126 -EPAPARR---------------------SVEQLRGIEGSRVRATYALLAKQY--GVTWN 161
            +  P  R                     S+  LRG+EG+   A +   A      + ++
Sbjct: 123 RDSEPHSRYLLTLSLRRLATSIAAVDEQGSLGSLRGLEGAGAAAYFEGFADLLPERLKFS 182

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYD 218
           GR   P      D +N  +S   + L+     A+  AG  P +GF H    G+  S   D
Sbjct: 183 GRNRRPPR----DPVNAMLSLGYTLLHAEAVLALYGAGLDPFVGFYHALDFGRE-SLACD 237

Query: 219 IADIIKFDT-----VVPKAFEIARRNPGEPDR--EVRLACRDIF---------RSSKTLA 262
           + + ++ +      ++ ++ ++        +    +  A R  F         R  K LA
Sbjct: 238 LVEPLRVEVDRHALMLFRSEKLRAEGFSTTESGCLLGKAGRARFYGEWEEVAARLRKLLA 297

Query: 263 KLIPLIED-VLAAGEIQPPAPPEDAQPVA 290
           + +  +   ++ A  ++ P  P    P A
Sbjct: 298 ESVSDVASAIMQAAAVEAPCSPPIGDPAA 326


>UniRef50_Q467D6 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Methanosarcina barkeri
           str. Fusaro RepID=Q467D6_METBF
          Length = 550

 Score = 67.0 bits (162), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 36/239 (15%), Positives = 77/239 (32%), Gaps = 29/239 (12%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           +       V+         +P+  ++ + +     +S   +R   ++   + +    G  
Sbjct: 234 VHKKGDRLVIKKNDEELQSVPLRQISQLSIYGDAHISLPVLRSLIEMNVPVCYFSFGGWF 293

Query: 85  VYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE---------LRFGEPAPARRSVE 135
              S        D  ++Q + A D +  L + RKM           LR  +   + + + 
Sbjct: 294 YGLSHGVMSKNVDLRIHQYQTAFDSERSLAISRKMIAGKIKNCRTLLRRNDTEVSEKILS 353

Query: 136 QL----------------RGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQC 179
           QL                 GIEG+  +  ++          + +  +       D +N  
Sbjct: 354 QLNSLEKKASNAKEIGQLLGIEGTAAQIYFSRFGNMLKQDLDCKFENRNKRPPTDPVNAV 413

Query: 180 ISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFEI 235
           +S     L       + + G+ P +GF H    GKP +   D+ +  +       A  +
Sbjct: 414 LSYLYGILTKEVFVTLFSVGFDPYMGFYHQPKYGKP-ALALDLMEEFRPLIADSVALTL 471


>UniRef50_A3CTI4 CRISPR-associated protein Cas1 n=1 Tax=Methanoculleus marisnigri
           JR1 RepID=A3CTI4_METMJ
          Length = 392

 Score = 67.0 bits (162), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 50/282 (17%), Positives = 92/282 (32%), Gaps = 32/282 (11%)

Query: 26  DVIDGAFVLIDKTGIRTH-IPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
            +      LI   G  T   P+ +V  +++  G  +  +AV    + G  +      G  
Sbjct: 97  HIKATTRELIIARGSDTRRYPIQAVKHLLIVGGHTLHTSAVTNLLKAGAAITIFDIDGTP 156

Query: 85  ---VYASGQPGGARSDKLL--------YQAKLALDEDLRLKVVRKMF-----------EL 122
              +Y  G                    Q         RL ++ +++           EL
Sbjct: 157 VGYLYPYGYRPDESVRLAQERAGPHRFAQPLARASLQSRLLLLEELYDHAGHDIFYAGEL 216

Query: 123 RF----GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQ 178
            F     E   A  ++E LR +        Y +L++        RR   + +   D +N 
Sbjct: 217 DFLHQAREELSASVTMENLRRLSRLTTDMYYEILSRTLPPELGFRRRTSRPYL--DPVNA 274

Query: 179 CISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR 238
             +   + +YG    +++ A   P +G +H G   SFV+D+ +  K   V       AR 
Sbjct: 275 MFALGYAMIYGNCCVSVVGAHLDPDLGMLHEG-AGSFVHDLIEPQKASMVDRAVIRFARE 333

Query: 239 NPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
                D E     +  +      ++L   + D +    I   
Sbjct: 334 EISSGDYEC--GEKRCYLGGDLSSRLAAALRDSIDQARIDAQ 373


>UniRef50_C3MWK6 CRISPR-associated protein Cas1 n=6 Tax=Sulfolobus
           RepID=C3MWK6_SULIM
          Length = 341

 Score = 67.0 bits (162), Expect = 8e-10,   Method: Composition-based stats.
 Identities = 42/272 (15%), Positives = 94/272 (34%), Gaps = 45/272 (16%)

Query: 4   LPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
           +      +KD  + + ++ G I        + D+  ++  I    +  I++   + +S  
Sbjct: 42  MDKKIAFVKDYGAYLKIEKGLI-----TCKIKDQ--VKWSIAPTELHSIIVLTNSSISSE 94

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPG--GARSDKLLYQAKLALDEDLRLKVVR---- 117
            V++A + G  +V+        YA   P          L Q      +  ++   +    
Sbjct: 95  VVKVANEYGIEIVFFNNN--EPYAKLIPAKYAGSFKVWLKQLTAW--KRRKVDFAKAFIY 150

Query: 118 ----------KMFELRFGEPAPARR------------SVEQLRGIEGSRVRATYALLAKQ 155
                     + +E ++G    ++             + E++   E    +  +  +   
Sbjct: 151 GKVHNQWVTLRYYERKYGYDLKSQELDRLAREVMFVNTAEEVMQKEAEAAKVYWRGVKSL 210

Query: 156 Y--GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGK 211
               + + GRR    D    D  N+ ++     L  V   A+++ G  P IGF+H     
Sbjct: 211 LPKSLGFKGRRKRVSD--NLDPFNRALNIGYGMLRKVVWGAVISVGLNPYIGFLHKFRSG 268

Query: 212 PLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            +S V+D+ +  +   V  K     R +  + 
Sbjct: 269 RISLVFDLMEEFRSPFVDRKLIGFVRESADKI 300


>UniRef50_B4W4R1 CRISPR-associated protein Cas1 n=1 Tax=Microcoleus chthonoplastes
           PCC 7420 RepID=B4W4R1_9CYAN
          Length = 354

 Score = 67.0 bits (162), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 43/270 (15%), Positives = 97/270 (35%), Gaps = 41/270 (15%)

Query: 11  LKDRVSMIFLQYGQ-IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
            ++  ++  ++ G  I      F++      +  +P+  V  I++    ++S   +++  
Sbjct: 18  HREMAAIYLIEQGTTIYKEYQRFIIYVSEKPKLEVPIREVQQILVFGNIQLSTPVMQVCL 77

Query: 70  QVGTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKM-FE------ 121
           +    +V++ ++G R +           D+ L Q +   D   + +V + + +       
Sbjct: 78  REQIAVVFLSQSG-RYHGHLWSSEFRDLDQELVQVRRWGDAAFQFQVSQAIVYGKLMNSK 136

Query: 122 ---LRFG-------------------EPAPARRSVEQLRGIEGSRVRATYALLAK---QY 156
              LRF                    E      S+++LRG EG      +  L +     
Sbjct: 137 QLLLRFNRKRKLPDVERAIIGINQDIEALEFSESLDRLRGYEGIGAARYFPALGQLITNS 196

Query: 157 GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS-- 214
              ++ R   P      D +N  +S   + L+      I+A G +P +G  H G+     
Sbjct: 197 RFEFSLRNRQPP----TDPVNSLLSFGYTLLFNNVLGFIIAEGLSPYLGNFHYGERQKPY 252

Query: 215 FVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
             +D+ + ++   V      I   +  +P 
Sbjct: 253 LAFDLMEEMRSVVVDSLVLNIVNHSLFKPQ 282


>UniRef50_C7G6C1 CRISPR-associated protein Cas1 n=3 Tax=Firmicutes
           RepID=C7G6C1_9FIRM
          Length = 334

 Score = 66.6 bits (161), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 45/264 (17%), Positives = 91/264 (34%), Gaps = 46/264 (17%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +++  Q   I +    F +  K G+   IP  ++  I +    +++   +    + G
Sbjct: 1   MSYLYVSEQGASIGIEANRFQVNYKDGMIKSIPAETLEMIEVFGSVQITTRCLTECLKRG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQ---AKLALDEDLRLK--------------V 115
             +++   +G   Y  G+        +  Q   A++  +E  +L+              V
Sbjct: 61  VNILFYSTSGA-YY--GRLISTSHVNVQRQRIQAEIGHNETFKLEMSKRIIDAKIRNQVV 117

Query: 116 VRKMFELRFGEPAPAR---------------RSVEQLRGIEGSRVRATYALLAKQYGVTW 160
           V + +  R  +    R               +SVEQ+ G EG+  +  + +L K     +
Sbjct: 118 VLRRYA-RGRDEDIHRMIIEMQNMQKKLLYAKSVEQVMGYEGTAAKIYFKVLGKLIDEQF 176

Query: 161 --NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFV 216
              GR   P      D  N  IS   S +       I   G  P  G +H  +    +  
Sbjct: 177 VFEGRSRRPP----MDPFNSLISLGYSIILNELYGKIEGKGLNPYFGVMHKDREKHPTLA 232

Query: 217 YDIADIIKFDTVVPKAFEIARRNP 240
            D+ +  +   +   A  +   + 
Sbjct: 233 SDLMEEWRAVLIDTTALSMLNGHE 256


>UniRef50_B9M9X7 Putative uncharacterized protein n=1 Tax=Diaphorobacter sp. TPSY
           RepID=B9M9X7_DIAST
          Length = 302

 Score = 66.6 bits (161), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 39/249 (15%), Positives = 81/249 (32%), Gaps = 23/249 (9%)

Query: 31  AFVLIDKTGIRTHIPVGSVACIMLE-PGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASG 89
            F L+ +      +P   +A I+L      ++H  +    + G  L   G+         
Sbjct: 18  HFALVVEQEQSARVPFEDIAVIVLNHREITLTHPVLSACGEYGIGLYSTGDNHQPNGVFM 77

Query: 90  QPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGS------ 143
                     + + +L LD+    +    + +++ G      R +E L G  G+      
Sbjct: 78  PFLQHSRATRMQRLQLDLDKPSAKRAWAHIVQVKIGNQ---ARCME-LLGTVGTDRLASY 133

Query: 144 --RVRA-----TYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAIL 196
             RVR+       A  +  Y     GR +           N  +    + + G    A++
Sbjct: 134 ARRVRSGDGGNLEAQASAYYFPQVFGRSFHRSQTGWS---NAALDYGYAVMRGACARALV 190

Query: 197 AAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDI 254
           A G  P++G  H  +  +F    D+ +  +    +  A         E     ++A   +
Sbjct: 191 AHGMLPSLGLFHRSEQNAFNLADDLIEPYRPVVDLHVAQHRPADEDAELQPSDKVALVGL 250

Query: 255 FRSSKTLAK 263
                 + +
Sbjct: 251 LNVDVAMPR 259


>UniRef50_A1HM55 CRISPR-associated protein Cas1 n=2 Tax=Thermosinus carboxydivorans
           Nor1 RepID=A1HM55_9FIRM
          Length = 332

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 51/264 (19%), Positives = 86/264 (32%), Gaps = 45/264 (17%)

Query: 18  IFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++      I    G F++     I   IP+  +  ++L    +VS   +    + G  L
Sbjct: 4   LYVTDAGSHIQKNAGRFLVCKGDTILREIPLELLDNVVLFGSIQVSAKTITEFLKRGITL 63

Query: 76  VWVGEAGVRVYASGQPGGARSD---KLLYQAKLALDEDLRLKVVRK---------MFELR 123
            W+ + G   Y  G+    R         Q ++    D  LK+ +          M  LR
Sbjct: 64  TWLSKTG-EFY--GRLESTRHIDIFLHRQQIRMGDRPDFCLKIAQAIIDAKIANCMTILR 120

Query: 124 --------------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWN 161
                                 E  P    +E L G+EGS  R  +  LA        + 
Sbjct: 121 RYQRTANSPEVADHIHAMGIIAEKIPNVDKIETLLGLEGSAARHYFTALACLVPDDFAFK 180

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDI 219
           GR   P      D  N  +S   + L       +  AG  P  GF+H  +    + V D+
Sbjct: 181 GRNKQPPK----DPFNSLLSFGYTLLMYDFYTIVQNAGLHPYAGFLHKDRQGHPTLVSDL 236

Query: 220 ADIIKFDTVVPKAFEIARRNPGEP 243
            +  +   +      +  R   +P
Sbjct: 237 MEEWRPSIIDSLVMSLIHRREIQP 260


>UniRef50_Q0AW57 CRISPR-associated protein, Cas1 family n=1 Tax=Syntrophomonas
           wolfei subsp. wolfei str. Goettingen RepID=Q0AW57_SYNWW
          Length = 336

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 46/265 (17%), Positives = 93/265 (35%), Gaps = 48/265 (18%)

Query: 15  VSMIFL-QY-GQIDVIDGAFVLIDKTGIRTHI-PVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +S +++ +   +I V +   V+  K      I P+  V  +++     +S   V+   + 
Sbjct: 1   MSFLYVYERSAKIGVQENCVVVESKKENLKRILPIEGVENVIIFGDASLSSNCVKQFMER 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLAL---DEDLRLKVVRKM--------- 119
              L W+   G + Y  G+    R+  +  Q K      D++  L + +++         
Sbjct: 61  DINLTWLSSRG-KFY--GRLESTRNVNIYRQRKQFACGEDDEFCLALAKRIILAKVKNQI 117

Query: 120 -----FELRFGEPAPARR---------------SVEQLRGIEGSRVRATYALLAK--QYG 157
                +     E +  +                + ++L G EG   R  Y  LA+  +  
Sbjct: 118 TILRRYRRNRPEKSVQKIIDAMAKLLPIMERVHNKDELMGHEGMAARYYYQGLAELVEPD 177

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLS 214
             ++GR   P      D  N  +S A + L      A +  G  P   F+H+   G P +
Sbjct: 178 FAFSGRNRQPPR----DPFNSLLSFAYTLLMYDLYTAAVNRGLNPYASFLHSIRRGHP-A 232

Query: 215 FVYDIADIIKFDTVVPKAFEIARRN 239
              D+ +  +       A  +  + 
Sbjct: 233 LCSDLMEEWRAILADSLALYVTSKG 257


>UniRef50_B9YDC3 Putative uncharacterized protein n=1 Tax=Holdemania filiformis DSM
           12042 RepID=B9YDC3_9FIRM
          Length = 343

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 39/260 (15%), Positives = 90/260 (34%), Gaps = 48/260 (18%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           + +     V++++  +   IP+ +++ I++     +S A +         L ++  AG  
Sbjct: 17  LSLDGENVVILNQQKVIKRIPLHNLSSIVMFNYQGISPALMGKCMSQNITLSFLSPAG-- 74

Query: 85  VYASGQPGGARSDKLLY--QAKLALDEDLRLKVVRKM------------------FELRF 124
            +     G  + + LL   Q  ++ +    L + + M                  + LR 
Sbjct: 75  YFLGRVVGEYQGNVLLRKKQILVSENNQQSLLIAKNMILAKVYNSKWILERAIRDYPLRI 134

Query: 125 GEP---------------APARRSVEQLRGIEGSRVRATYAL-----LAKQYGVTWNGRR 164
                                 +S ++LRG+EG+  +  ++      L ++    +  R 
Sbjct: 135 DIEKMRVIFKKLSEILNSIEKVQSHDELRGLEGTAAKLYFSSFDDLILRQKEDFVFTTRT 194

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKP--LSFVYDIADI 222
             P      + +N  +S   + L     +A+ + G    IGF H  +P  +S   D+ + 
Sbjct: 195 RRPP----LNKVNALLSFVYTLLSHDCASALESVGLDCYIGFFHVDRPGRMSLALDLMEE 250

Query: 223 IKFDTVVPKAFEIARRNPGE 242
            +          +  R   +
Sbjct: 251 FRPCLADRFVLSLINRKEID 270


>UniRef50_C3WS02 CRISPR-associated protein n=2 Tax=Fusobacterium RepID=C3WS02_9FUSO
          Length = 335

 Score = 65.8 bits (159), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 40/291 (13%), Positives = 99/291 (34%), Gaps = 40/291 (13%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            I+ Q   +   +   ++    G    IP+ ++  +++  G ++S A +      G  + 
Sbjct: 5   YIYEQGIVLRYKENRLLITYTNGDYKSIPIENIDNVVIFGGIQLSTACMHNLLIKGIHVT 64

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAK------------------------------LA 106
           ++ + G      G+     +  +  Q +                              + 
Sbjct: 65  FLSKTGSYF---GRLESTSNINIDRQREQFRKSDDKKFCLAIGKKFIKGKATNQRTLLIR 121

Query: 107 LDEDLRLKVVRKMFELRFG--EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRR 164
            ++DL+ +++  +    FG  +     +++E+L G+EG   R  +  +       ++ + 
Sbjct: 122 ANKDLKSEILSSVINSMFGIIKDINDSKTIEELMGVEGYLARLYFNAINHIIDKKYSFKT 181

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADI 222
              +  +  D  N  IS   + L+      ++  G  P   F+H+ +    +   D+ + 
Sbjct: 182 RTKRPPK--DPFNAVISFGYTLLHYEIFTTLVTKGLNPYAAFLHSDRHKHPALCSDLMEE 239

Query: 223 IKFDTVVPKAFEIARRNPGEPDR-EVRLACRDIFRSSKTLAKLIPLIEDVL 272
            +   V   A  +   N    +          +F + K   K +   E  L
Sbjct: 240 WRAILVDSMAIALLNNNKIAYEDFNFDEKSGGVFLNKKACGKFVEQFEKRL 290


>UniRef50_B7A8Y4 CRISPR-associated protein Cas1 n=1 Tax=Thermus aquaticus Y51MC23
           RepID=B7A8Y4_THEAQ
          Length = 316

 Score = 65.8 bits (159), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 8/152 (5%)

Query: 134 VEQLRGIEGSRVRATYALLAKQYGVT-WNGRRYDPKDWEKGDTINQCISAATSCLYGVTE 192
           +E LRG EG   RA +  L +      + GR   P      D +N  +S   + L G   
Sbjct: 137 LESLRGAEGEGSRAYFQGLGRLLAAQGFGGRTRRPPR----DPVNAALSYGYALLLGRVL 192

Query: 193 AAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
            A+  AG  P +GF+H     S     D+ +  +   V        RR    P       
Sbjct: 193 VAVRLAGLHPEVGFLHAEGRRSPALALDLMEEFRVPVVDAVVLSAFRRGHLTP-AHAEAR 251

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAP 282
              ++ + +   +LI L+E         P   
Sbjct: 252 EGGVYLNEEGRRRLIELLEGRFLEEVAHPLGF 283


>UniRef50_Q2NH78 Putative uncharacterized protein n=1 Tax=Methanosphaera stadtmanae
           DSM 3091 RepID=Q2NH78_METST
          Length = 332

 Score = 65.8 bits (159), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 47/288 (16%), Positives = 97/288 (33%), Gaps = 39/288 (13%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           G +   +      +K  + T IP+ ++  I       +   A+ L  +   ++ +  + G
Sbjct: 19  GILYRKENTLKFKNKE-VDTSIPIHAINEINCYGKVSLRSGAISLLQKEKIIINFFNKYG 77

Query: 83  VRVYAS---GQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------------FELRFG 125
              Y      +        ++ QA    +E+ R  + ++M              ++ +  
Sbjct: 78  --YYEGSLYPKIALNSGVIVVKQALTYNNENKRCFIAKEMVNGMKHNMIKTLKYYKKKGK 135

Query: 126 EPAPARRSVE----------QLRGIEGSRVRATYALLAKQYG-VTWNGRRYDPKDWEKGD 174
           +     +++E          ++   EG   ++ Y              R + P   E   
Sbjct: 136 DVDEHIQNLENESILDGNINRILSSEGKLWQSYYPSFDNITKKFPIEKREFKPPKNE--- 192

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKA 232
            +N  IS   S LY  T + I      P+I F+H  +    S   D+ADI K   +    
Sbjct: 193 -MNSLISYGNSLLYTTTLSEIYHTYLHPSISFLHEPRERRFSLACDLADIFKPLIISRTI 251

Query: 233 FEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
           F++   N    ++  +     ++ + K   K I    + L      P 
Sbjct: 252 FKLVNTNIIN-EKHFKKDV-GVYLNEKGRQKFIQEYNNKLKTTIKHPQ 297


>UniRef50_Q2RY11 CRISPR-associated protein, Cas1 family / CRISPR-associated
           exonuclease, Cas4 family n=2 Tax=Rhodospirillum rubrum
           ATCC 11170 RepID=Q2RY11_RHORT
          Length = 580

 Score = 65.4 bits (158), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 40/241 (16%), Positives = 75/241 (31%), Gaps = 42/241 (17%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
            +I   D   V+  +      + +  ++ ++L     ++  A+    +    + W+    
Sbjct: 255 ARIGKKDYTLVIQVEGEADRSLALDEISEVVLAGPVSLTTPAIHELLRREIPVAWMSSGF 314

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE--------------------- 121
             + ++G  G   +     Q  LA DE  R    R +                       
Sbjct: 315 WFLGSTGGQGPRSAAVRTAQYALAGDERRRQAFARDLVSAKIRNGRTLLRRNWRGAEAER 374

Query: 122 -------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--------GVTWNGRRYD 166
                   R  E A    +   L GIEG      +    + +           +  R   
Sbjct: 375 QIALDRLARLAERATTAETTACLLGIEGEAAAVYFRAFPQLFTQAVTTLPAFAFERRNRR 434

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIK 224
           P      D +N C+S   + L     +A+  AG  P  GF HT +P   +   D+ +  +
Sbjct: 435 PP----ADPVNACLSLCYAVLTRTLSSALSIAGLDPWKGFYHTERPGRPALALDLIESFR 490

Query: 225 F 225
            
Sbjct: 491 P 491


>UniRef50_A8ABE8 CRISPR-associated protein Cas1 n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8ABE8_IGNH4
          Length = 310

 Score = 65.4 bits (158), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 24/110 (21%), Positives = 42/110 (38%), Gaps = 11/110 (10%)

Query: 145 VRATYALLAKQYGVTWNG-RRYDPKD----WEKGDTINQCISAATSCLYGVTEAAILAAG 199
           V+   A  + +    W    ++ P          D  N+ +    + LY V   A++ AG
Sbjct: 153 VKKLEAEWSSKL---WKDIVQFVPGMRSRVPRGNDPPNRTLDYLYALLYSVCNHALVGAG 209

Query: 200 YAPAIGFVHTGK--PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREV 247
             P  G +H  +   LSFVYD +++ K    +       R    E + + 
Sbjct: 210 LDPYAGLIHRERAGKLSFVYDFSEMFKP-MAIYVMATAIRTYKIELEGDF 258


>UniRef50_C8WTR3 CRISPR-associated protein Cas1 n=2 Tax=Alicyclobacillus
           acidocaldarius RepID=C8WTR3_ALIAD
          Length = 346

 Score = 65.4 bits (158), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 48/270 (17%), Positives = 92/270 (34%), Gaps = 49/270 (18%)

Query: 18  IFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTL 74
           +F+Q     + V     V+  +      +P+  V  I+   G    +   +   A  G  
Sbjct: 9   LFVQREGAIVRVHQDTVVVTLENETLLRVPMHMVDSIV-GIGRVSFTSPLLERCAAEGRS 67

Query: 75  LVWVGEAGVRVY-----------------ASGQPGGARSDKLLYQA--KLALDEDLRLKV 115
           +V +   G  +Y                  + +        +      K+     L LK 
Sbjct: 68  VVRMTRGGRFLYRIEGRMSGNVLLRTAQHEAARSPERSLTIMRAIVAGKVHNQRQLVLKA 127

Query: 116 VRKMFE---LRFGEP-----------APARRSVEQLRGIEGSRVRATYALL------AKQ 155
            R +       F               P+    +++RG+EG+  R  +  L      A +
Sbjct: 128 ARDLTAPADRSFVREVAGDLGRELRKLPSASHPDEIRGVEGASARRYFMALRHLIAPAIR 187

Query: 156 YGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL-- 213
             ++++GR   P      D +N  +S   + +    E+A+L  G  P IGF+HT +P   
Sbjct: 188 DALSFDGRNRRPPR----DPVNAVLSFLYALITRDAESALLGVGLDPQIGFLHTLRPGRP 243

Query: 214 SFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
           S   D+ + ++          +  R   +P
Sbjct: 244 SLALDLVEEMRPILADRVMLSLFNRRQLQP 273


>UniRef50_Q74N45 NEQ017 n=1 Tax=Nanoarchaeum equitans RepID=Q74N45_NANEQ
          Length = 333

 Score = 65.0 bits (157), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 50/264 (18%), Positives = 85/264 (32%), Gaps = 47/264 (17%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           ++  L  G++         I+K   ++ IP+ S+  I +     V++ A++L A     +
Sbjct: 3   TIYILSIGKLYRGKNGLYFINKDKKKSPIPLESIKEIFILNKVSVTYNALKLLADRNIPI 62

Query: 76  VWVGE---AGVRVYASGQPG---GARSDKLLYQAKLALDEDLRLKVV------------- 116
            +  E    G+  Y               L+ Q +   D + R ++              
Sbjct: 63  HFFYENTKKGISYYLGSFLPRQKTKSGLVLVKQVEAYKDIEKRTEIALEIVDAIRYNCIK 122

Query: 117 ------------------RKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGV 158
                              KMFE    +   A   +  +RGIE +     Y  L K   +
Sbjct: 123 VLEKYHIDEVKELRKIDVWKMFEESLNDWKDA---INIIRGIESNIWNLFYQGLDKILKL 179

Query: 159 -TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSF 215
                R   P   E     N  +S A + LYGVT   I      P I F+H       S 
Sbjct: 180 YKLERRTRRPPKNEA----NTIVSFANTLLYGVTLTEIYKTHLDPTISFLHELRDTRYSL 235

Query: 216 VYDIADIIKFDTVVPKAFEIARRN 239
             D+++  K          +  + 
Sbjct: 236 ALDLSENFKPIITFRILIWLVNQG 259


>UniRef50_B3PMY9 Putative uncharacterized protein n=1 Tax=Mycoplasma arthritidis
           158L3-1 RepID=B3PMY9_MYCA5
          Length = 297

 Score = 64.6 bits (156), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 51/280 (18%), Positives = 96/280 (34%), Gaps = 28/280 (10%)

Query: 33  VLIDKTGIRTHIPVGSVACIMLEPGT-RVSHAAVRLAAQVGTLLVWVGEAGVR-VYASGQ 90
           ++++K G +  IP   +  ++ E     ++   +      G  ++  G   +        
Sbjct: 21  LVVNKDGTKITIPTSQIDTVLFENDKLTITLPLINDLVDHGINIIVCGRNHMPKAQIIPF 80

Query: 91  PGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRG-----IEGSR- 144
            G   +  L  Q K   D D + +V R++ +L+  +       +  LR      +E    
Sbjct: 81  QGYYNAKILQKQIKW--DNDFKERVWRRIIKLKIRQTMVMLEHLAILRDDDKVKLEDYAN 138

Query: 145 ------VRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAA 198
                 +       AK       G ++  K     DT N  ++   S L      AI + 
Sbjct: 139 SVKAFDITNCEGHCAKLNFKILFGEKFVRKTNTMEDTYNAYLNYGYSVLLSYVARAICSK 198

Query: 199 GYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPD-REVRLACRDIF 255
           GY   +G  H           D+ +  +   V    ++  R + GEP+ +E +     IF
Sbjct: 199 GYDNRLGIFHRSYSNFYPLACDLMEPFRC-IVESLVYKHVRISRGEPNFQEFKEELFTIF 257

Query: 256 RSS-------KTLAKLIP-LIEDVLAAGEIQPPAPPEDAQ 287
                       L   I  L+  VL+  +I+ P     A+
Sbjct: 258 YKHFNCQGENLMLIDCIDKLVVLVLSDHDIKGPYFNWSAE 297


>UniRef50_A0LWB2 CRISPR-associated protein Cas1 n=1 Tax=Acidothermus cellulolyticus
           11B RepID=A0LWB2_ACIC1
          Length = 295

 Score = 64.6 bits (156), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 48/255 (18%), Positives = 86/255 (33%), Gaps = 33/255 (12%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           G++    GA ++ D+      +P+  VA ++  P   +  + +  AA  G  +V     G
Sbjct: 15  GEVHAAQGALLVGDER-----VPLVDVAMMLTGPYVSLHGSVIDRAAAFGVGVVHCDWRG 69

Query: 83  VRVYA--SGQPGGARSDKLLYQAKL--------ALD--EDLRLKVVRKMFELRFGEPAPA 130
           V V A          + +   QA+L         ++  +         +  LR    A  
Sbjct: 70  VPVAATLPWSTHNRVAARHRAQAELSLPRQKNAWMNIVKTKIRNQAAVLRALRRDGVAQL 129

Query: 131 RRSVEQLRG-----IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
            R   Q+R       EG+  R  +A L       +  + +        D +N  +    +
Sbjct: 130 ERLAAQVRSGDASNAEGAAARVYWARL-------FQDKHFRRV-PRARDVVNGLLDYGYA 181

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEP 243
            L G    A++ AG AP++G  H      F    D+ +  +   V     EI        
Sbjct: 182 ILRGCCLRAVVGAGLAPSLGLWHRRHDNPFTLVDDLIEPFRPA-VDKTVIEIVTAGASGL 240

Query: 244 DREVRLACRDIFRSS 258
           DR  +     +    
Sbjct: 241 DRPTKRLLVAVLDHQ 255


>UniRef50_Q0ADY5 CRISPR-associated protein, Cas1 family n=2 Tax=Nitrosomonas
           RepID=Q0ADY5_NITEC
          Length = 328

 Score = 64.6 bits (156), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 38/228 (16%), Positives = 77/228 (33%), Gaps = 41/228 (17%)

Query: 18  IFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +F+      +++  GA V  +       +P+  +  + L    ++  A +    + G  +
Sbjct: 4   LFVDRRGVVLELESGAIVFRENGERIGTVPIAPLTRVFLRGDVKLPAALLGKLGEQGVGV 63

Query: 76  V-WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP----- 129
           V   G  G       +P    + + + Q +L+ D+   L++ + + E +           
Sbjct: 64  VILSGRIGRPSLLLARP-HNDAARRVVQIRLSFDKPFCLQIAKALIERKLTRQIEWFAEL 122

Query: 130 --------------------------ARRSVEQLRGIEGSRVRATYALLAKQY--GVTWN 161
                                        S   LRG+EGS     ++ L       + ++
Sbjct: 123 RENDMQVRYELSHALRALEEHRSRIGHVSSAASLRGVEGSAAARYFSGLQAVVPDSLHFS 182

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
           GR   P      D  N  +S   + L+     A+   G+ P +GF H 
Sbjct: 183 GRNRRPPR----DPFNALLSLTYTLLHSEIAIALYGTGFDPYVGFYHR 226


>UniRef50_B8D4S7 CRISPR-associated protein Cas1 n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D4S7_DESK1
          Length = 328

 Score = 64.6 bits (156), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 31/161 (19%), Positives = 61/161 (37%), Gaps = 27/161 (16%)

Query: 118 KMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLA----KQYGVTWNGRRYDPKDWEKG 173
           +M E  F E        E+LR +E    R  +  L+    K+ G       ++ +D +  
Sbjct: 146 RMLEAEFEEA------REKLRQLEAEAARIYWPSLSILIPKELG-------FNSRDQDSE 192

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPK 231
           D +N  ++ A   LYG +   ++ AG  P  GF+HT +       +D+ ++ +       
Sbjct: 193 DLVNTSLNYAYGILYGESWKVLVLAGLDPYAGFMHTDRSGKPVLAFDLIEMFR------- 245

Query: 232 AFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
            F              +    +     ++ A+++  I   L
Sbjct: 246 -FTADSTLLAMYRHGWKPRVLNGLLDYESRARIVESIMKTL 285


>UniRef50_C8PKY6 Putative CRISPR-associated protein Cas1 n=1 Tax=Campylobacter
           gracilis RM3268 RepID=C8PKY6_9PROT
          Length = 731

 Score = 64.3 bits (155), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 42/249 (16%), Positives = 88/249 (35%), Gaps = 38/249 (15%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           + +  G  VL  K  I+   P+  ++ I++     +S A ++  A+    + ++ E    
Sbjct: 421 LALSQGKLVLKSKGAIKHKFPINQISQIIINAQISLSSAVIKECAKKKISINFIDEKTNL 480

Query: 85  VYASGQPGGAR-SDKLLYQAKLALDEDLRLKVVRKM-----------------FELRFGE 126
            YA+     +        Q  L   +   L++ ++                  +    G 
Sbjct: 481 SYATLISANSAIPKTAASQISLLTTKKS-LRIAQQFIIGKLKNQINYLKYLGKYHKNLGA 539

Query: 127 PA-----------PARRSVEQLRGIEGSRVRATYALLAKQ--YGVTWNGRRYDPKDWEKG 173
                        P   SV +L G EGS   + +  +AK   Y   ++ R          
Sbjct: 540 EIKAMQEILKLRVPGAASVSELMGFEGSAANSYWQAIAKAVDYEFGFSARVTQ----GAT 595

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPK 231
           D +N  ++   + LY     +I AAG +P + ++H    +  +  +D+ +  +   V   
Sbjct: 596 DIVNSALNYGYAILYSKILKSIAAAGLSPHVSYLHALDEQKPTLAFDLIEEFRAFIVDRA 655

Query: 232 AFEIARRNP 240
              +  +N 
Sbjct: 656 VISMVNKNE 664


>UniRef50_A3ZPG0 Putative uncharacterized protein n=1 Tax=Blastopirellula marina DSM
           3645 RepID=A3ZPG0_9PLAN
          Length = 331

 Score = 64.3 bits (155), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 48/277 (17%), Positives = 94/277 (33%), Gaps = 37/277 (13%)

Query: 35  IDKTGIRTH-IPVGSVACIMLE-PGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPG 92
             + G   H IP   +  ++++ PGT  +HAA+R  A     +V  G   +   A+    
Sbjct: 59  FKREGAVVHTIPCEEIGVVVIDHPGTTYTHAALRQLAASDAAVVICGANHLP--AAILLP 116

Query: 93  GARSD----KLLYQA--------KLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGI 140
            A       +L+ Q         +L       ++           +  P R+ ++ L  +
Sbjct: 117 LADHSEVVWRLVEQIEAPKPLCKRLW---RQIVRAKIDAQASVLPDDCPGRQKLKSLIPL 173

Query: 141 E--GSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAA 198
              G       A  AK Y   W       +D +  D +N  ++   +        AI++A
Sbjct: 174 VKPGDAA-NVEARAAKTYWQFWYPEAGFRRDADS-DGVNALLNYGYAIARAAIARAIVSA 231

Query: 199 GYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFR 256
           G  PA+G  H  +   F    D+ +  +   V  +  E+ R+      +E +     +  
Sbjct: 232 GLTPALGLHHRNRSNPFCLADDLIEPFRP-MVDERVRELHRQGYDSLTQECKGELLKLLA 290

Query: 257 SSKTLA-----------KLIPLIEDVLAAGEIQPPAP 282
              +L            +++  +   L   +     P
Sbjct: 291 RQTSLDGEKGPFMVQLHRMLGSLVRCLRKKQTSLEIP 327


>UniRef50_D2R8Z2 CRISPR-associated protein Cas1 n=1 Tax=Pirellula staleyi DSM 6068
           RepID=D2R8Z2_9PLAN
          Length = 942

 Score = 64.3 bits (155), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 52/262 (19%), Positives = 96/262 (36%), Gaps = 40/262 (15%)

Query: 20  LQYGQIDVIDGAFVLIDKTGIRTHIPVGSV-ACIMLEPGTRVSHAAVRLAAQVGTLLVWV 78
           ++   +      F   D+ GI + IP+ ++   ++L     +SH  +    Q    L+ +
Sbjct: 622 IEEILVHGDVLQFKHQDQRGIES-IPLHTLREVVVLG-AVSLSHRVLSAIQQNAISLLLL 679

Query: 79  GEAGVRV-YASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM-------FE--------- 121
            E+  R  Y   Q     S  +  Q  L  + +  L + R++       +          
Sbjct: 680 DESANRTAYIDCQNAEPDSAGIEAQVDLIRNPESSLAIARQLISAKLHNYATLADAYPPK 739

Query: 122 ----------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKD 169
                     +R  + A    S+ +L GIEGS     Y  +  +   G  W  R      
Sbjct: 740 SHSGNAHRSLMRLAKDAQQASSLPELLGIEGSGAALWYGEIGMRLSPGFHWERR----VA 795

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDT 227
               D +N  ++ A + LY +T+ AI  A     +GF+H  +    +   D+ +  +   
Sbjct: 796 PNAHDPVNILLNLAQTVLYRMTQHAIAQAKLVDTLGFLHQPRAGHAALASDMQEPFR-HL 854

Query: 228 VVPKAFEIARR-NPGEPDREVR 248
           +     E  RR  P E + + R
Sbjct: 855 MDRAVLETVRRIRPEEFEPDER 876


>UniRef50_B5IAF4 CRISPR-associated protein Cas1 n=3 Tax=Euryarchaeota
           RepID=B5IAF4_9EURY
          Length = 404

 Score = 64.3 bits (155), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 35/213 (16%), Positives = 67/213 (31%), Gaps = 49/213 (23%)

Query: 59  RVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRK 118
            +S  A+R   +    +  +   G  +              + Q ++ ++E  RLK+  K
Sbjct: 50  NISFEAIRWLMKHNITVSVLNWNGNLLSVFLPKEPINGKLKIRQYEIYINEKERLKIAEK 109

Query: 119 ------------MFE--------------------------LRFGEPAPARRSVEQLRGI 140
                       ++E                          +   E    + S   L   
Sbjct: 110 ILEEKIRKSENMLYELSEYYPEIEHIKVKKRIEKEEKLKRDMELKEENKPKLSY--LLMY 167

Query: 141 EGSRVRATYALLAKQYG-----VTWNGRRYDPKDWE--KGDTINQCISAATSCLYGVTEA 193
           EG   +  +  L+K +        +  R      W     D IN  ++ + + L  +   
Sbjct: 168 EGRVAQIYWKELSKIFNKLYPEFNFTSRSTKSYSWNMNASDEINALLNYSYALLESMIRK 227

Query: 194 AILAAGYAPAIGFVHT--GKPLSFVYDIADIIK 224
            I A G  P+IGF+H         VYD+ ++ +
Sbjct: 228 HINAVGLDPSIGFLHELASSKTPLVYDLQELFR 260


>UniRef50_C9RRG3 CRISPR-associated protein Cas1 n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RRG3_FIBSS
          Length = 343

 Score = 63.9 bits (154), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 51/320 (15%), Positives = 98/320 (30%), Gaps = 45/320 (14%)

Query: 18  IFL-QYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++ + G ++    G  V+         I +  V  + L      +  A+      G  +
Sbjct: 3   LYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADI 62

Query: 76  VWVGEAG-------------VRVYASGQPGGARSDKLLYQAK--LALDEDLRLKVVRKMF 120
            ++   G             V +           D+    AK  +    +  L+V+    
Sbjct: 63  AFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYS 122

Query: 121 E-----LRFGEPAP-----------ARRSVEQLRGIEGSRVRATYALLAK--QYGVTWNG 162
           +      RF                     ++LRG EG+  R  +    +    G+ + G
Sbjct: 123 KNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPG 182

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIA 220
           R+Y P      D +N  +S   +      E+ + + G  P +G++H       S   D+ 
Sbjct: 183 RKYHP----STDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDML 238

Query: 221 DIIKFDTVVPKA-FEIARRNPGEPDREVRLACR---DIFRSSKTLAKLIPLIEDVLAAGE 276
           +  +   V     F   RR     D E R        +F   + +   +   ED +A   
Sbjct: 239 EEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPN 298

Query: 277 IQPPAPPEDAQPVAIPLPVS 296
                         + L V 
Sbjct: 299 GIYQGLANLPWRSVMRLRVE 318


>UniRef50_Q2J7N9 CRISPR-associated protein Cas1 n=1 Tax=Frankia sp. CcI3
           RepID=Q2J7N9_FRASC
          Length = 344

 Score = 63.5 bits (153), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 45/253 (17%), Positives = 77/253 (30%), Gaps = 47/253 (18%)

Query: 25  IDVIDGAFVLI--DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           + +   A  +   D    R  +P+  V  I++  G  ++   ++  A     + W+   G
Sbjct: 17  LHLDGDAVRIWHPDNDKGRRLLPLVRVDHIVVFGGVTITDDLLQRCATDRRSVTWLTGNG 76

Query: 83  VRVYASGQPGG--------------ARSDKLLYQA------KLALDEDLRLKVVR----- 117
            R  A  +                    ++ L  A      KL     L L+  R     
Sbjct: 77  -RFRARVEGPTGGNPHLRIAQHDHFRDDERRLTLAMSYIAGKLQNSRQLLLRAARDATGT 135

Query: 118 KMFELR-----FGEPAPA---RRSVEQLRGIEGSRVRATYALLAK-----QYGVTWNGRR 164
           +   LR       +  P      +V +  G+EG   R   A                GR 
Sbjct: 136 RQTALRDTAAHLADALPTLRDTTNVAEAMGVEGQAARRYIATWPHLLTPHATVTAPAGRT 195

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADI 222
             P      D +N  +S     L      A+   G  P IG++H  +P   +   D+ + 
Sbjct: 196 SRPA----TDPVNAALSFGYGILRIAVHGALDHVGLDPHIGYLHGIRPGKPALALDLMEE 251

Query: 223 IKFDTVVPKAFEI 235
            +   V    F  
Sbjct: 252 FRALLVDRLVFTA 264


>UniRef50_Q1J1U7 CRISPR-associated protein Cas1 n=1 Tax=Deinococcus geothermalis DSM
           11300 RepID=Q1J1U7_DEIGD
          Length = 342

 Score = 63.5 bits (153), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 38/227 (16%), Positives = 76/227 (33%), Gaps = 22/227 (9%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV 83
           ++         + + G             M   G  +   A    A      + +     
Sbjct: 59  RLAREHKPVTWLSEHGRFM----ARTETPM--SGNVLLRTAQHACAGNAARTLAI----A 108

Query: 84  RVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGS 143
           R+ A+G+    +   L    +   D+   L+   +   ++     P   +V+++RG EG+
Sbjct: 109 RLIAAGKLQNQKVTLLRAAREAEADDAALLRQAARDINVQIA-CLPLTETVDEVRGTEGT 167

Query: 144 RVRATYA----LLAKQYGVTW-NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAA 198
             R  +     +L +     W + R   P      D IN  ++   + L     +A  A 
Sbjct: 168 AARLYWEVFPLMLRQNRDFFWLSERHRRPAR----DPINALLNFVYTVLANDCASACQAV 223

Query: 199 GYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
           G  P +GF+H  +P   S   D+ + ++          +  R    P
Sbjct: 224 GLDPQLGFLHALRPGRSSLALDLMEELRPVIADRAILTLINRQQLTP 270


>UniRef50_D0MKP4 CRISPR-associated protein Cas1 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MKP4_RHOM4
          Length = 525

 Score = 63.5 bits (153), Expect = 9e-09,   Method: Composition-based stats.
 Identities = 45/286 (15%), Positives = 90/286 (31%), Gaps = 56/286 (19%)

Query: 8   PIPLKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIR----THIPVGSVA-CIMLEPGTRV 60
            +P   +   +++      +       V+      R      +P   V   +++ P  ++
Sbjct: 178 IMPPVRQARTLYVDEIGAVVRRKGRQLVVTVSRDGRRQELLRVPALLVDQVVLVGP-VQI 236

Query: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGAR-SDKLLYQAKLALDEDLRLKVVRKM 119
           +  A+R+  +    +V++   G R                L Q +   D +  L + R  
Sbjct: 237 TSQALRMLLRRNVDIVYLSGEG-RFEGRLAAEFHPHVALRLAQYEAFRDPERTLTLARLF 295

Query: 120 FE----------LRFGEP-------------------APARRSVEQLRGIEGSRVRATYA 150
                        R+ +                         ++E LRG+EG+  R  ++
Sbjct: 296 VRGKLQNMAGLLRRYADEYGSASLRAAASEINRDLERLEQVTTLEALRGVEGTASRRYFS 355

Query: 151 LLAKQYGVT---------WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYA 201
           +  +              + GR   P      D +N  +    + L G   AA   AG  
Sbjct: 356 VFGEMLRAEAYAPTGWPAFPGRHRRPP----TDPVNATLGYLYALLLGNVVAACALAGLD 411

Query: 202 PAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           P +G++H    G+P S   D+ +  +       A  +  R    P 
Sbjct: 412 PYVGYLHAPAYGRP-SLALDLMEEFRAPAADRLALRLFNRGRLRPQ 456


>UniRef50_B2RM83 CRISPR-associated protein Cas1 n=3 Tax=Bacteroidetes
           RepID=B2RM83_PORG3
          Length = 338

 Score = 63.1 bits (152), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 46/285 (16%), Positives = 83/285 (29%), Gaps = 51/285 (17%)

Query: 16  SMIFLQYGQIDVIDGAFVLI---------DKTGIRTHIPVGSVACIMLEPGTRVSHAAVR 66
           +      G++   D     +         ++ G   +IPV  ++   +    R + +   
Sbjct: 4   TYYLFNPGELSRKDNTIRFVPIQEGENGQEQAGQARYIPVEGISDFYVFGSLRANSSLYN 63

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVRKM---- 119
                   + +        Y               LL QA    ++  RL + RK     
Sbjct: 64  FLGSNDIAVHFF--DYYENYTGSFMPRDFLLSGKMLLAQASAYKNKKKRLFLARKFIEGA 121

Query: 120 ----------FELRFGEPAP-------------ARRSVEQLRGIEGSRVRATYALLAKQY 156
                     +  R  +  P                ++E L GIEG+ +R  Y       
Sbjct: 122 ASNMQKNLAYYNNRGKDMQPMMELIDKYSLRLEETTTIEALMGIEGN-IRQAYYDAFNLI 180

Query: 157 GVTWN--GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL- 213
              +    R   P   E    +N  IS      Y +   AI  +   P I F+HT     
Sbjct: 181 IDPFEMGARSKQPPQNE----VNALISFGNMMCYTLCLKAIHQSQLNPTISFLHTPGERR 236

Query: 214 -SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRS 257
            S   DI+++ K   V    F++  +   +  +           +
Sbjct: 237 YSLCLDISEVFKPILVDRTIFKVMNKRIIQA-KHFDKQLNKCILN 280


>UniRef50_B1YCK7 CRISPR-associated protein Cas1 n=2 Tax=Thermoproteaceae
           RepID=B1YCK7_THENV
          Length = 303

 Score = 63.1 bits (152), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 47/269 (17%), Positives = 88/269 (32%), Gaps = 44/269 (16%)

Query: 31  AFVLIDKTGIRTHIPVGSVACI-MLEPGTRVSHAAVRLAAQVGTLLVWVGEAG---VRVY 86
           A V+  + G    IP+  V  + +L  G  +S   VR  A+    +V+    G    R++
Sbjct: 18  ALVVRRRGGAAERIPIHQVDRLWILTGGVSISSRLVRALARSFVDVVFFDGRGNPAARLF 77

Query: 87  ASGQPGGARSDKLLYQAKL---------------ALDEDLRLKVV----RKMFELRFGEP 127
                G     +  Y+A L                +++   L+      R++++   G  
Sbjct: 78  PPEANGTVAHRRAQYEAYLNGRGLELAKLVVYGKIVNQAAALRRAGLWRRELYQELAGAA 137

Query: 128 ---------APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQ 178
                     P     + + G EG      +A L+K +G          +D    D  N 
Sbjct: 138 SRVAEAAAAVPRCGDPQCVLGHEGRAAAEYWAALSKAFGTP-------TRDPNASDPFNL 190

Query: 179 CISAATSCL-YGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEI 235
            ++     L Y V   A++  G  P  G++H  K    S V D+ +  +    +    + 
Sbjct: 191 ALNYGYGILRYAVWRQAVIH-GLDPYAGYLHVDKSGRPSLVLDLMEEFRPHIDL-MVLKA 248

Query: 236 ARRNPGEPDREVRLACRDIFRSSKTLAKL 264
                      ++   R          +L
Sbjct: 249 KPSADWLEGGVLKREARAALVEKWLEMRL 277


>UniRef50_C0QR16 Crispr-associated protein Cas1 n=23 Tax=Bacteria RepID=C0QR16_PERMH
          Length = 331

 Score = 63.1 bits (152), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 43/284 (15%), Positives = 86/284 (30%), Gaps = 38/284 (13%)

Query: 23  GQIDVIDGAFVLIDKTGIRT---HIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVG 79
           G++   +       +         +P+  +  I +     ++  A+   +     + +  
Sbjct: 11  GRLRRKENTLYFETEQNGEIVKKALPINDIDVIYVFGELDINTKALNYLSGYDIPIHFYN 70

Query: 80  EAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVV------RKMFELR------- 123
             G   Y+              L+ Q +  +D   R  +            LR       
Sbjct: 71  YYG--FYSGSFLPRKKNVSGSLLVEQVRHYIDNKKRQYLAVSFVEGAAYHILRNLRKQNI 128

Query: 124 ------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWE 171
                       F +    R + E+L  +EG+ +R  Y  L  +     +      +   
Sbjct: 129 NSEDFEEIEKDLFPKIFETRNT-EELMALEGN-IRERYYQLFNKIINNEDFFMEKREKRP 186

Query: 172 KGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVV 229
             + IN  IS   S +Y      I      P I ++HT   K  S   D+A+I K   + 
Sbjct: 187 PDNPINALISFGNSIMYNTVLTEIYRTQLDPTISYLHTPQEKRFSLSLDLAEIFKPFIID 246

Query: 230 PKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
           P  F +         ++        + +     K +   E+ L+
Sbjct: 247 PLIFSLINNRQITI-KDFDKDLNYAYLNENGRKKFLKAYEERLS 289


>UniRef50_O28401 Putative uncharacterized protein n=1 Tax=Archaeoglobus fulgidus
           RepID=O28401_ARCFU
          Length = 345

 Score = 62.3 bits (150), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 12/120 (10%)

Query: 134 VEQLRGIEGSRVRATYALLA----KQYGVTWNGRRYDP--KDWEKGDTINQCISAATSCL 187
            E+L GIEG   +  +  ++    ++Y   +NGRR           D +N  ++   S L
Sbjct: 161 RERLLGIEGKASKHYWDAISLVIPEEYR--FNGRRGIEIGSPRYAKDIVNAMLNYGYSIL 218

Query: 188 YGVTEAAILAAGYAPAIGFVH---TGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
                 A+  AG  P  GF+H   +G+  S   D+ +  +   V      +      +P+
Sbjct: 219 LAECVKAVELAGLDPYAGFLHVDVSGRS-SLAIDLMENFRQQVVDRVVLRLISYRQIKPE 277


>UniRef50_B4ATI8 Crispr-associated protein Cas1 n=5 Tax=Proteobacteria
           RepID=B4ATI8_FRANO
          Length = 318

 Score = 62.3 bits (150), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 22/116 (18%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 122 LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCIS 181
            R  +     +++  + G EG      ++ LAK   ++ +    + +     +  N  ++
Sbjct: 138 KRVAQLIKNAKTLNDVLGYEGYAANIYFSSLAKDKFLSASF--ANREGRGSQEIANSMLN 195

Query: 182 AATSCLYGVTEAAILAAGYAPAIGFVHTGKP--LSFVYDIADIIKFDTVVPKAFEI 235
              + L      AI  AG  P +GF+H  +P  +S V D+ +  +   V     ++
Sbjct: 196 FGYAILSSYILNAITNAGLEPYLGFLHQKRPGKMSLVLDLMEEYRAWVVDRVVIKL 251


>UniRef50_O66692 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=O66692_AQUAE
          Length = 316

 Score = 61.9 bits (149), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 38/248 (15%), Positives = 74/248 (29%), Gaps = 42/248 (16%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
           +G +   +      +   ++  IPV  V  I                +    LL ++   
Sbjct: 10  HGTLSRHENTLRFENAE-VKKDIPVEDVEEIF----------VFAELSLNTKLLNFLASK 58

Query: 82  GVRVY-----------ASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM---------FE 121
           G+ ++              +        L+ Q +  LD   RL + +           + 
Sbjct: 59  GIPLHFFNYYGYYTGTFYPRESSVSGHLLIKQVEHYLDAQKRLYLAKSFVIGSILNLEYV 118

Query: 122 LRFGEPA-----PARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
            +              S+ +L  +E    +  Y  L +  G     R   P      + +
Sbjct: 119 YKISADTYLNKVKETNSIPELMSVEAEFRKLCYKKLEEVTGWELEKRTKRPPQ----NPL 174

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIADIIKFDTVVPKAFE 234
           N  IS   S  Y      I      P + ++H  + K  S   D+A++ K   V      
Sbjct: 175 NALISFGNSLTYAKVLGEIYKTQLNPTVSYLHEPSTKRFSLSLDVAEVFKPIFVDNLIIR 234

Query: 235 IARRNPGE 242
           + + N  +
Sbjct: 235 LIQENKID 242


>UniRef50_C4FMU2 Putative uncharacterized protein n=1 Tax=Veillonella dispar ATCC
           17748 RepID=C4FMU2_9FIRM
          Length = 331

 Score = 61.9 bits (149), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 43/266 (16%), Positives = 81/266 (30%), Gaps = 42/266 (15%)

Query: 15  VSMIFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +++      I    G  V+     +   +P+  +  I +     ++ + V    + G
Sbjct: 1   MSSLYVTEAGSFIKRDGGHVVVGRNNEVLFEVPLERIEDITVFDSVSITSSLVTDFIERG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM------------- 119
             + W+   G              +K   Q  L  D   R+ + RK+             
Sbjct: 61  VPITWLSGYGKYFGTLINTNTIDINKHKKQFDLLDDNAFRVAMSRKIIRAKVRNQLTILR 120

Query: 120 -FELRFGEPAP----------------ARRSVEQLRGIEGSRVRATYALLAK--QYGVTW 160
            +     E                       V +L G EG   R  +  L K       +
Sbjct: 121 RYARNLEEDINIDAQIANIKSVRSHIGECMRVSELMGYEGLISRLYFEALGKIVPSAFAF 180

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVY 217
             R   P      D  N  +    S L+    A ++ AG  P +G +H+   G P +   
Sbjct: 181 TKRTKQPPR----DPFNAMLGLGYSMLFNEILAGVINAGLHPFVGIMHSLAKGHP-ALAS 235

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEP 243
           D+ +  +   +      +  RN  + 
Sbjct: 236 DLIEEWRAPIIDSMVLSMVSRNMVDL 261


>UniRef50_Q1Q3I6 Putative uncharacterized protein n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1Q3I6_9BACT
          Length = 328

 Score = 61.9 bits (149), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 33/251 (13%), Positives = 75/251 (29%), Gaps = 39/251 (15%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGE 80
           Q   +       ++     +   +    +  +++    + +  AV    + G  +  +  
Sbjct: 4   QNSILRKSGDRLIIEKDDKVLLEVQCHKIDAVLIFGNVQFTTQAVHELFEHGIEMAILTR 63

Query: 81  AGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR--------------KMFELRFG- 125
            G  +     P        + Q K   ++D RL   +              + F      
Sbjct: 64  TGKLIGQITSPYTKNITLRVQQFKQYWNDDFRLAFAKVIVCGKIQNCIQLVRSFSYNHPR 123

Query: 126 --------------EPAPARRSVEQLRGIEGSRVRATYALLAKQ--YGVTWNGRRYDPKD 169
                             +  ++ QL GIEG+  R  +    K       + GR+  P  
Sbjct: 124 NSFDVEMDDLSLRLNEVESAANISQLFGIEGNAARVYFTSFGKMILSAFAFPGRKKYP-- 181

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKFD 226
               D +N  +S   + ++    + +   G+ P +G+ H    G+  S   D+ +  +  
Sbjct: 182 --STDPVNALLSLNYTMIFNEISSLLDGLGFDPYLGYYHGIDYGRS-SLASDLMEEFRAP 238

Query: 227 TVVPKAFEIAR 237
                   +  
Sbjct: 239 IADRITLNLIN 249


>UniRef50_A2SRR7 CRISPR-associated protein, Cas1 family n=24 Tax=cellular organisms
           RepID=A2SRR7_METLZ
          Length = 344

 Score = 61.9 bits (149), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 42/327 (12%), Positives = 97/327 (29%), Gaps = 72/327 (22%)

Query: 11  LKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSV-ACIMLE-----PGTRVSH 62
           ++   +++++      +     + V+  +      +P+ ++   +        PG     
Sbjct: 1   MRKLRNVLYVTNPKSYLSRDGESIVVSVENQELARVPIRNLEGVVCFGYMGASPGM---- 56

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR----- 117
             + L  +    + +V   G  +   G            Q  ++ DE+   K+       
Sbjct: 57  --MALCTENDVGMCFVSPYGKFMARIGGNVSGNVLLRKRQYAVSDDEEASKKIAAYCILG 114

Query: 118 -----KMFELRFGEPAPARRSVE------------------------QLRGIEGSRVRAT 148
                +    RF    P   S E                        +LRG EG   +  
Sbjct: 115 KLMNCRTVLQRFSRDYPDMVSREFEQNFKRLSEGILQIRAGTCGSLNELRGFEGILSKYY 174

Query: 149 YAL-----LAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPA 203
           +       L+ +   ++  R   P      D +N  +S + + +     +A+ + G  P 
Sbjct: 175 FHSFNDLILSTEPEFSFENRSRRPP----LDRVNALLSFSYTLIAADCASALESVGLDPQ 230

Query: 204 IGFVHTGKPL--SFVYDIADIIKFDTVVPKA-------------FEIARRNPGEPDREVR 248
           +GF+H  +P   S   D+ +  +                     F +          + R
Sbjct: 231 VGFLHRVRPGRPSLALDLMEEFRPYLGDRFVLSLINNRVVKADDFAVKENGAVLLTDDAR 290

Query: 249 LACRDIFRSSKTLAKLIPLIEDVLAAG 275
                 ++  K    +   +E+ +  G
Sbjct: 291 KTVLQAWQKRKKEEVMHGYLEEKMPVG 317


>UniRef50_Q2FQQ2 CRISPR-associated protein Cas1 n=2 Tax=Methanomicrobia
           RepID=Q2FQQ2_METHJ
          Length = 347

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 49/291 (16%), Positives = 93/291 (31%), Gaps = 30/291 (10%)

Query: 10  PLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTH-IPVGSVACIMLEPGTRVSHAAVRLA 68
            L+D    I   YG+I +  G   + D  G      P+  V  + +     VS   ++  
Sbjct: 25  LLEDDTIYITTPYGKISLDGGRIQVKDSDGEIVASFPLEKVCTMNVFGSASVSTPLLKHC 84

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQ------------------AKL----A 106
           +    ++ +    G + + S  P       +                     AKL     
Sbjct: 85  SDKEVVINYFTNFG-KYFGSFVPSRNTIALVRRHQAGITKEKSLAICREIIHAKLQNSCV 143

Query: 107 LDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYD 166
                R++V   + ELR  + +    SV+ LRGIEG      + +L+      W  R   
Sbjct: 144 FLARKRVEVPSLLKELR--DRSLHAVSVDSLRGIEGEAASIYFPMLSSSLPDEW--RSDK 199

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIK 224
                  D +N  +S   + +     +A+      P IG +H  +    +   D+ +  +
Sbjct: 200 RTRRPPRDELNALLSLTYTMVNTEVISALRQYNLDPFIGVMHVDRHGKPALALDLLEEFR 259

Query: 225 FDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
                     +  +     D   + +  +     K L      +E+ L   
Sbjct: 260 PVFCDAFVARLINKRMITKDDFTQGSRLNDTAFKKYLGFYHDFMEESLKHP 310


>UniRef50_B8G918 CRISPR-associated protein Cas1 n=5 Tax=Chloroflexi (class)
           RepID=B8G918_CHLAD
          Length = 339

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 61/317 (19%), Positives = 107/317 (33%), Gaps = 52/317 (16%)

Query: 18  IFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++  Q  +I        +     I   +P+  +  I++     +S  A++     G  +
Sbjct: 4   LYVIEQGAEIGCDGERIEVRRGADIIGSVPLVKLDDIVIFGNVGISTPAMKRLLDRGIEV 63

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLA--LDEDLRLKVVRKMFE----------LR 123
            ++   G   Y     G   +   L  A+ A   D    L + ++  E           R
Sbjct: 64  TFMTVDG--RYQGRLIGQVTAHVALRHAQYACAADPARALALAQRFVEGKLRNQRALLQR 121

Query: 124 FG----EPAP-----------------ARRSVEQLRGIEGSRVRATYALLAKQYGVTWN- 161
           F     EP P                     +  L G+EGS     +A L    G  W+ 
Sbjct: 122 FSRNRAEPPPEAQAAADDLEAYIKRVKRTTQLSSLLGVEGSATARYFAGLRSLIGPEWSF 181

Query: 162 -GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVY 217
            GR+  P      D +N  +S   + L      A+ AAG+ P +GF+H+   G+P S   
Sbjct: 182 SGRQRRPP----PDPVNLLLSLGYTLLAHKVLGAVQAAGFDPYLGFLHSLDYGRP-SLAL 236

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVR--LACRDIFRSSKTLAKLIPLIEDVLAAG 275
           DI +  +   +      I       P+   R     R I  + +     +   E+ +   
Sbjct: 237 DIMEEFRPILIDSLVVRICNDGRIRPE-HFRPGEGERPIIITDEGKRAFLTAFEERMRTE 295

Query: 276 EIQPPAPPEDAQPVAIP 292
              P     D+ P  +P
Sbjct: 296 ATHPEGA--DSGPGKVP 310


>UniRef50_C5SD37 CRISPR-associated protein Cas1 n=1 Tax=Allochromatium vinosum DSM
           180 RepID=C5SD37_CHRVI
          Length = 346

 Score = 61.6 bits (148), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 58/273 (21%), Positives = 94/273 (34%), Gaps = 54/273 (19%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT---------- 73
           Q+ +  GA  L+       HIP+G +  +++     V     R  A+ G           
Sbjct: 15  QLTLDGGALRLVTPGTKPRHIPLGVLGLVVVHGRALVGCDVWRALAERGIPAVMQPGRGR 74

Query: 74  -LLVW----VGEAGVRVYASGQPGGARSDKL-----------LYQAKL------ALDEDL 111
            +  W    +G  GV   A  +       +L           L QA++      A D   
Sbjct: 75  GVCAWMGPALGATGVLRAAQHRAAEQVERRLMLARDLIAAKLLAQARVIERLPVASDPPE 134

Query: 112 RLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW--NGRRYDPKD 169
               VR+  +L       A  + E + G+EGS   A +  L      TW   GR   P  
Sbjct: 135 TRTAVRRQQDLALARLGQASSTTEVM-GLEGSAAAAWFRWLTLWLSPTWGFQGRNRRPPR 193

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIK-- 224
               D +N  +S   + L G   + I   G  PA G +H    G+  S V D+ + ++  
Sbjct: 194 ----DPVNALLSLGYTLLGGEMLSVIQQQGLDPARGLLHELVPGRE-SLVLDLIEPLRPS 248

Query: 225 ---------FDTVVPKAFEIARRNPGEPDREVR 248
                       + P+ F  +  +     +E R
Sbjct: 249 VDLVLLGMLDRLLTPEDFTTSPEDGCRLSKEAR 281


>UniRef50_Q3B3C1 CRISPR-associated protein, Cas1 family n=20 Tax=Bacteria
           RepID=Q3B3C1_PELLD
          Length = 343

 Score = 61.2 bits (147), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 36/219 (16%), Positives = 71/219 (32%), Gaps = 46/219 (21%)

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLY----------QAKLALDE----- 109
           +   A  G  + ++ E G +     Q     +  L            Q+ +         
Sbjct: 57  MGHCAANGVTVTFLTEYG-KFLCQVQGPTKGNILLRRAQYRQADNYLQSAMLARSFVIGK 115

Query: 110 --DLRLKVVRKM---------FELRFGEPAPAR--------RSVEQLRGIEGSRVRATYA 150
             + R+ + R +          ++ + +   A            E++RGIEG   R  + 
Sbjct: 116 IGNSRVTLARALRDHPDKIDCEKMHYAQQLLAGCIKKLGNETDQERIRGIEGEAARIYFE 175

Query: 151 LL-----AKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIG 205
           +      +      +NGR   P      D +N  +S   + +     +A+ + G  PA G
Sbjct: 176 VFDQCITSSDPLFCFNGRNRRPP----VDRVNCLLSFLYTLVTHDIRSALESCGLDPAAG 231

Query: 206 FVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           F+H  +P   S   D+ +  +       A  +  R    
Sbjct: 232 FLHKDRPGRPSLALDMLEEFRSYIADRMALSLINRGQIH 270


>UniRef50_C0W0W5 CRISPR-associated Cas1 family protein n=1 Tax=Actinomyces
           coleocanis DSM 15436 RepID=C0W0W5_9ACTO
          Length = 287

 Score = 61.2 bits (147), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 52/284 (18%), Positives = 97/284 (34%), Gaps = 30/284 (10%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           GQI    GA  +         +P+  VA +++      S  A+      G  ++     G
Sbjct: 3   GQISSARGAISIEPDGKEPVLVPISDVAVLLIGHRVVFSGGALHRCLSAGVAVMLCDWRG 62

Query: 83  VRVYAS--GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGI 140
           V    +         + + + QA+L   E  R    +++ + +    A +      LRG 
Sbjct: 63  VPEGGAFGWSDHTRVAARRIAQAQL--SEPRRKNAWKQIIKEKLRGQA-SALDDLGLRGG 119

Query: 141 EGSR-VRATYAL------LAKQYGVTWN-----GRRYDPKDWEKGDTINQCISAATSCLY 188
           +  R +R            A+     W      G    P        +N  +  A + + 
Sbjct: 120 DFLRELRKQVRSGDPANVEAQAAKFYWKALGGEGFNRVPGARFG---VNGMLDYAYAIVR 176

Query: 189 GVTEAAILAAGYAPAIGFVHTGKPLSF--VYDIADIIKFDTVVPKAFEIARRNPGEPDR- 245
           G    A+L+AG  P++G  H G+  +F  V D+ ++ +   V  + F +      E D  
Sbjct: 177 GHGIRAVLSAGLEPSLGVFHHGRSNAFCLVDDLLEVFRPA-VDAQVFGLLGDGEVEFDEV 235

Query: 246 ---EVRLACRDIFRSSKTLAKLIPLIEDVLA---AGEIQPPAPP 283
               V +AC        T+  +              +++   PP
Sbjct: 236 KHDLVDIACGKFSVDGLTIPAVFEDFAQQFGLYIEDDVEKLVPP 279


>UniRef50_B3E1C9 CRISPR-associated protein Cas1 n=1 Tax=Methylacidiphilum infernorum
           V4 RepID=B3E1C9_METI4
          Length = 217

 Score = 60.8 bits (146), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 24/111 (21%), Positives = 43/111 (38%), Gaps = 6/111 (5%)

Query: 122 LRFGEP---APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQ 178
           +RF          R +  +RG EG   R  +   A+Q      G        +  D +N 
Sbjct: 14  VRFKRACVGLVHARQLPAVRGWEGWASRHYWRWFAQQVN-QLGGFEERRTHGQTQDPVNL 72

Query: 179 CISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDT 227
            ++   + L      A+  AG  P +G +H   G+  + V D+ +I + + 
Sbjct: 73  ALNYGYALLRHRLGVAVRLAGLDPYLGVLHEANGRHEALVSDLVEIFRPEV 123


>UniRef50_D2QAN8 CRISPR-associated protein Cas1 n=2 Tax=Bifidobacterium dentium
           RepID=D2QAN8_9BIFI
          Length = 305

 Score = 60.8 bits (146), Expect = 6e-08,   Method: Composition-based stats.
 Identities = 47/260 (18%), Positives = 85/260 (32%), Gaps = 38/260 (14%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGE 80
           + G++ V                +P+   A +++      S A +   A+ G  ++    
Sbjct: 20  ERGRMKVRK------HGESESVCVPLAQAAVVLIGLRVCCSSAVLHEMAKAGVSVMLCDW 73

Query: 81  AGVRVYASGQPGGARSDKLLYQ-----AKLALDEDLRLKVVRKMFELRFGEPAPARRSVE 135
            G+   A        S+  + Q       L   ++   K+V+   ++R          +E
Sbjct: 74  RGIPDAALHSWTNVPSEVAVRQIAQSEMTLPRKKNAWAKIVKA--KIRGQASCLDSLGIE 131

Query: 136 ---QLRGI------------EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180
               LRGI            EG   R  +  +        +G+R+       G   N  +
Sbjct: 132 GGGALRGIASSVRSGDTSNYEGYAAREYWKRI-----FIGDGKRFKRI-PGDGTGRNAQL 185

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARR 238
             A + L G    AIL+AG  P +G  H G+   F    D+ ++ +       A      
Sbjct: 186 DYAYTILRGFAVKAILSAGLIPTLGVNHHGRSNYFCLADDLLEVYRPAIDYWVA--QLEP 243

Query: 239 NPGEPDREVRLACRDIFRSS 258
             G  D+ V+    D     
Sbjct: 244 EDGPSDKNVKRYLADSVNQQ 263


>UniRef50_C6HZN2 CRISPR-associated protein Cas1 n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HZN2_9BACT
          Length = 245

 Score = 60.4 bits (145), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 47/242 (19%), Positives = 86/242 (35%), Gaps = 46/242 (19%)

Query: 18  IFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT-L 74
           ++L      +DV +G+ +L ++      IP+  +  +++     +S A +   ++ GT  
Sbjct: 4   LYLDRKGLDLDVENGSLILREEGERIRSIPLTFLDRVVIRANISLSSAVLGELSESGTET 63

Query: 75  LVWVGEAG-----------------VRVYASGQPGGARSDKL--------LYQAK----- 104
           +V  G  G                 +R YA       R              QA+     
Sbjct: 64  VVLSGRQGRKVARIEGSRHNDARIRLRQYALFHDTTLRKRWAGRLVRSKIRSQARSLGTI 123

Query: 105 LALDEDLRLKVVRKMFELRFGEPAPARRSVE-----QLRGIEGSRVRATYALLAKQY--G 157
           L +  DL   ++R M +L+        R+++     +L G+EG      +   +K +   
Sbjct: 124 LKVRPDLTSSLLRPMEQLQSIGEKIRERTLDPFEISELLGLEGGAGSLYFESFSKAFPPS 183

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSF 215
           + +  R   P      D  N  +S A + L+          G  P IGF H       S 
Sbjct: 184 LGFTSRNRRPPR----DPANAVLSLAYTLLHFDGVRTANMVGLDPLIGFYHEPAYGRDSL 239

Query: 216 VY 217
           V+
Sbjct: 240 VF 241


>UniRef50_B8DWG2 CRISPR-associated protein Cas1 n=4 Tax=Bifidobacterium animalis
           subsp. lactis RepID=B8DWG2_BIFA0
          Length = 535

 Score = 60.0 bits (144), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 32/249 (12%), Positives = 68/249 (27%), Gaps = 37/249 (14%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
            +  +  G   +       T +P+ S+  + +     VS   +R        ++W    G
Sbjct: 219 ARAYLKSGRMHVSKNGDEITSVPLDSIQALQIHGNVDVSSGLMRELMWRNIPILWCSGTG 278

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP------------- 129
            R+          + +    A+     + RL + R+    +                   
Sbjct: 279 -RLMGWSVSSYGPNGET-RVAQHVASHEGRLDLAREFISAKIHNQIVLLRRSDKNNNVLF 336

Query: 130 ----------ARRSVEQLRGIEGSRVRATYALLAKQYGV------TWNGRRYDPKDWEKG 173
                         ++ +  +EG      ++       V       W  R   P      
Sbjct: 337 DMKHIEKSVVNANRIQDILSLEGQAAALYFSQFHHLISVNKRNEWPWLERMRHPA----P 392

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPK 231
           D +N  +    S L      AI++ G     GF+H+ K    +   D+ +  +       
Sbjct: 393 DPLNALLDYTYSLLLSDCIRAIVSCGLDAHAGFLHSSKRNKPALALDLMEEFRAPIADSV 452

Query: 232 AFEIARRNP 240
              +     
Sbjct: 453 VQTVVNNGE 461


>UniRef50_B5IHG3 CRISPR-associated protein Cas1 n=3 Tax=Aciduliprofundum boonei T469
           RepID=B5IHG3_9EURY
          Length = 321

 Score = 60.0 bits (144), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 51/284 (17%), Positives = 93/284 (32%), Gaps = 34/284 (11%)

Query: 18  IFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVW 77
           +++    I   +   + + + G +  IP+ ++  I        S  A++     G ++ +
Sbjct: 4   LYITKEAIIKREANTIYLVRKGEKRSIPIHNLRDITCIAPVSFSSGAIKHVLNSGVVVHF 63

Query: 78  VGEAGVRVYASGQPGGARS---DKLLYQAKLALDEDLRLKVVRKMFE------------- 121
               G   Y        RS   + ++ QAK  +  + R  + ++M E             
Sbjct: 64  FDMYG--NYEGTLYPRERSISGEVVVNQAKHYIFWEKRKYIAKEMIEGIKHNILRNLKKS 121

Query: 122 --------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG-VTWNGRRYDPKDWEK 172
                    +         S+E+L   E       Y  L           R Y P   E 
Sbjct: 122 NKELEEIIEKIERVEVEGDSIEELMNREAQIWGYYYKSLDYTLKKFQLERRDYRPPINE- 180

Query: 173 GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVP 230
              +N  IS   + LY      I      P+I ++H       S   DIAD+ K   V  
Sbjct: 181 ---LNALISFGNTLLYSAVLTEIYHTHLNPSISYLHEPSERRFSLSLDIADVFKPTMVYR 237

Query: 231 KAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
              +I        + + R     +F + +   K I   ED +++
Sbjct: 238 HIHDIVNHGII-TEDDFRKEFNGVFLNEQGKRKYIRKWEDRMSS 280


>UniRef50_A5UJ50 Uncharacterized protein predicted to be involved in DNA repair n=5
           Tax=Methanobrevibacter RepID=A5UJ50_METS3
          Length = 334

 Score = 60.0 bits (144), Expect = 9e-08,   Method: Composition-based stats.
 Identities = 19/115 (16%), Positives = 42/115 (36%), Gaps = 8/115 (6%)

Query: 132 RSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
            S  ++ G EG      +  ++      + +  R   P++    D +N  ++   + L  
Sbjct: 156 TSKNKIMGFEGIASVNYWEAVSLLLPDEINFKKRNQKPEN----DVVNSMLNYGYAILAS 211

Query: 190 VTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGE 242
                I+  G  P  G +H    +  S ++D+ +  +   V    F++   N   
Sbjct: 212 EIAKNIVTLGLDPYCGLLHADLKRRQSLIFDLIEEFRQQIVDKTVFKLINTNQIN 266


>UniRef50_Q8YWX6 Alr1468 protein n=4 Tax=Cyanobacteria RepID=Q8YWX6_ANASP
          Length = 668

 Score = 60.0 bits (144), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 42/238 (17%), Positives = 80/238 (33%), Gaps = 39/238 (16%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           + V +  F +  +  +R  +PV  V+ ++L     VSH AV +A +    ++++ + G R
Sbjct: 347 LSVKNQQFQVFHQGELRIKVPVMRVSNVVLFGCCNVSHGAVSMALRRRIPIMYLSQKG-R 405

Query: 85  VY--------------------ASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL-- 122
            +                            +  + + +AKL     L LK+ R+      
Sbjct: 406 YFGRLQTEGDAKVEYLMLQVERCQNHEFTRKQAEAIVRAKLHNSRALLLKLNRRHPSKIA 465

Query: 123 --------RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEK 172
                      E      S++ LRG EG      +  L   +     +  R   P     
Sbjct: 466 ATAISGIAELMEKLSLAESMDSLRGYEGKAATLYFQGLGSLFTGAFVFEKRTKRPP---- 521

Query: 173 GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIADIIKFDTV 228
            D +N  +S   + L     + +   G     G +H       + V D+ +  +   V
Sbjct: 522 TDPVNSLLSLGYTLLSQNVFSFVQVIGLHTHFGNLHVPRDNHPALVSDLMEEFRAQLV 579


>UniRef50_A6DE65 Putative uncharacterized protein n=1 Tax=Caminibacter
           mediatlanticus TB-2 RepID=A6DE65_9PROT
          Length = 267

 Score = 60.0 bits (144), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 29/142 (20%), Positives = 53/142 (37%), Gaps = 11/142 (7%)

Query: 133 SVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTE 192
            +++L G EGS     +  ++K      N   +        D IN  ++   + LY   +
Sbjct: 96  KIDELMGYEGSIANIYWNGISKIL----NEEDFKRITKGATDRINTALNYGYAILYNKVQ 151

Query: 193 AAILAAGYAPAIGFVHT-GKPLSFVYDIADIIKFDTVVP-KAFEIARRNPGEP---DREV 247
            A++ AG    I F+HT  K    V+D  +  +   V     F + + +  +        
Sbjct: 152 KALIKAGLGINISFLHTFEKKPVLVFDFIEQFRCVAVDKAICFSLKKSDDIDVNNKGMLT 211

Query: 248 RLACRDIFRSSKTLAKLIPLIE 269
           R A R I    +   +L    +
Sbjct: 212 REAKRRIV--EEVNERLATFYK 231


>UniRef50_A0LHZ4 CRISPR-associated protein, Cas1 family n=2 Tax=Deltaproteobacteria
           RepID=A0LHZ4_SYNFM
          Length = 350

 Score = 59.6 bits (143), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 31/142 (21%), Positives = 51/142 (35%), Gaps = 13/142 (9%)

Query: 130 ARRSVEQLRGIEGSRVRATYAL---LAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
            ++ ++ LRGIEG      + +   L +  G  +NGR   P      D +N  +S   + 
Sbjct: 147 RQKDMDLLRGIEGHAANLYFEVFPLLVRVPGFEFNGRNRRPP----LDPLNALLSFVYTL 202

Query: 187 LYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
           L      AI   G  P +G +H    G+P S   D+ +  +          +  R     
Sbjct: 203 LTQEVLTAIKVVGLDPYLGCLHAVDYGRP-SLACDLVEEWRTFLGDRLVLALVNRRVIGL 261

Query: 244 DREVRL--ACRDIFRSSKTLAK 263
           D  V     C D     +   +
Sbjct: 262 DDFVYRPTPCADAVDEEELKHR 283


>UniRef50_C0WRP8 CRISPR-associated protein n=18 Tax=Lactobacillaceae
           RepID=C0WRP8_LACBU
          Length = 327

 Score = 59.6 bits (143), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 47/223 (21%), Positives = 88/223 (39%), Gaps = 19/223 (8%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTR--VSHAAVRLAAQVGT 73
           S+I  Q+ ++       ++    GI   IP+  ++ +++   TR  ++ A +   AQVGT
Sbjct: 31  SVIITQHAKLSYSSHMMIVQTNDGIN-QIPIDDISILLIST-TRAVITTALISELAQVGT 88

Query: 74  LLVWVGEAGVR-VYASGQPGGARSDKLLYQAKLALDEDLRLK----VVRKMFE----LRF 124
            +++   A        G     RS KLL +     ++   +     V  KM      L F
Sbjct: 89  KVIFTDGANQPICETVGYYPNNRSVKLLQEQVNWDEQRKEVLWTKIVASKMINQVNVLTF 148

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +      + E+L  +E +      A++A++Y        +  ++   G  IN  +    
Sbjct: 149 YKKDTTEVN-EELAKLEVADPSNREAVVARKYFPLLFNNDFSRRN---GSAINAALDYGY 204

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKF 225
           S L       I++ GY   IG  H G+   F    D+ +  + 
Sbjct: 205 SILLSSINQEIVSNGYLTYIGIHHRGEDNPFNLGSDLMEPFRP 247


>UniRef50_Q8TVS6 Uncharacterized conserved protein n=1 Tax=Methanopyrus kandleri
           RepID=Q8TVS6_METKA
          Length = 331

 Score = 59.6 bits (143), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 52/242 (21%), Positives = 87/242 (35%), Gaps = 40/242 (16%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           ++IFL+ G+I+  + AF +    G   +  V +   I+   G +++  AVRLA +    +
Sbjct: 7   TVIFLRRGKIERREDAFRI----GKSKYSAVRTTGIIIAG-GAQITTQAVRLALRNEVPI 61

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE---------LRF-- 124
           V++G   +            +   L Q ++A     RL   R +           L F  
Sbjct: 62  VYLGGNRILGVTVPFSE-RYATLRLKQYEIASQPSARLAFARPLIASSILARAAVLEFLA 120

Query: 125 ------------------GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYD 166
                              E A    S + LRG EG      +  LA+     W      
Sbjct: 121 NETGITGLEDAADEVRSEAERALNAGSTDALRGYEGRAACRYFRALAEVLP-DW-AFSGR 178

Query: 167 PKDWEKGDTINQCISAATS-CLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIADII 223
                  D  N  IS   +  L  V  +  +AAG  P +GF+H   G+    + D+ +  
Sbjct: 179 RTRRPPRDPFNAAISFGYAGVLLPVLLSRTVAAGLEPFLGFLHGPRGRRPGLILDLMEEW 238

Query: 224 KF 225
           + 
Sbjct: 239 RA 240


>UniRef50_B0JKW9 CRISPR-associated protein Cas1 n=6 Tax=Cyanobacteria
           RepID=B0JKW9_MICAN
          Length = 334

 Score = 59.2 bits (142), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 34/181 (18%), Positives = 67/181 (37%), Gaps = 11/181 (6%)

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEG 142
           VR +  G+    R+  L  Q      ++L L+      E   G       +++ LRG+EG
Sbjct: 104 VRGFVRGKLKNYRNILLRRQRD---RKELDLQTAIACLEAAIG-SIETTSAIDSLRGLEG 159

Query: 143 SRVRATYALL-AKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYA 201
           +   A ++   +   G T+     + +     D +N  +S   + L    ++AI   G+ 
Sbjct: 160 AGSAAYFSCFDSLILGDTFTFASRNRRPPR--DPVNSLLSLGYALLRHDVQSAINLVGFD 217

Query: 202 PAIGFVH---TGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSS 258
           P +G++H    G+P S   D+ +  +   V              P+             +
Sbjct: 218 PYLGYLHYQRYGRP-SLALDLMEEFRAIVVDAVVLNGVNHPYLTPEHFTTEPLSGAVSLT 276

Query: 259 K 259
           +
Sbjct: 277 R 277


>UniRef50_C6I8L1 CRISPR-associated protein n=1 Tax=Bacteroides sp. 3_2_5
           RepID=C6I8L1_9BACE
          Length = 756

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 29/143 (20%), Positives = 54/143 (37%), Gaps = 16/143 (11%)

Query: 136 QLRGIEGSRVRATY---ALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTE 192
           +L  IE     A +    +L    G+ +  R +        D +N  ++   + LY    
Sbjct: 584 ELMAIESQAAIAYWSYIRVLTADDGIDFIRREHQ----GATDLLNSLLNYGYAILYARVW 639

Query: 193 AAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
             ILAA   P+IG +H  +    + V+D+ ++ +   V      +         ++V L 
Sbjct: 640 KNILAAKLNPSIGVLHAKQDGKPTLVFDVVELFRAQMVDRVVISL-------IQKKVSLK 692

Query: 251 CRDIFRSSKTLAKLIPLIEDVLA 273
             D   +  +   LI  I + L 
Sbjct: 693 MHDGLLNESSKRVLIRYILERLN 715


>UniRef50_B9LX94 CRISPR-associated protein Cas1 n=2 Tax=Halobacteriaceae
           RepID=B9LX94_HALLT
          Length = 331

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 41/260 (15%), Positives = 78/260 (30%), Gaps = 32/260 (12%)

Query: 16  SMIFLQY--GQIDVIDGAFVLIDKTGIRTHI---PVGSVACIMLEPGTRVSHAAVRLAAQ 70
           S++++     Q+    G   + D  G    +   P   +  I +  G   S   V  A +
Sbjct: 11  SVVYVTKQGSQVGTEGGRITVWDVDGDEGELASFPTEKLDTINVFGGVNFSTPFVAEANR 70

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA-- 128
            G +L +  + G   Y         +   + +A+  LDE   + +   M   +       
Sbjct: 71  HGIILNYFTQNGK--YRGSFVPEKNTIAEVRRAQYDLDETAEIDIAADMIAAKIRNARTL 128

Query: 129 ----------------PARRSVEQ---LRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD 169
                               +V     LRG+EG      +  L +     W   +   + 
Sbjct: 129 LSRKGVHGTELLKDLGVRATTVATKDGLRGVEGEAAERYFNRLDETLTDGWTFEKRTKRP 188

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDT 227
            E  D IN  +S     +     +A+      P +G +H  +    S   D+ +  +   
Sbjct: 189 PE--DHINSLLSLTYVFMKNEVLSALRQYNLDPFLGVLHADRHGRPSLALDLQEEFRPIF 246

Query: 228 VVPKAFEIARRNPGEPDREV 247
                  +  R     D   
Sbjct: 247 CDAFVTRLVNRGVITHDEFT 266


>UniRef50_Q1WVJ8 CRISPR-associated protein n=1 Tax=Lactobacillus salivarius UCC118
           RepID=Q1WVJ8_LACS1
          Length = 301

 Score = 58.9 bits (141), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 40/217 (18%), Positives = 85/217 (39%), Gaps = 17/217 (7%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTR-VSHAAVRLAAQVGTLLVWVG 79
           Q+ ++   + A ++ +K GI   IP+  +  +++      ++ A V   A+ G  +++  
Sbjct: 10  QHSKLSYSNNAMIVQNKDGIN-QIPLVDMDILLISTTQAVITSALVSKLAESGIKVIFTD 68

Query: 80  EAGVRVY-ASGQPGGARSDKLLYQAKLALDEDL--------RLKVVRKMFELRFGEPAPA 130
                V          RS     Q     D           R K++ ++  L+  +    
Sbjct: 69  NKNEPVTETVNYYPNNRSLDTYLQQYEWNDHVKEILWTKIVRSKIINQIKVLKNYQIDCQ 128

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
              +E L  +E + +    A++A++Y     G +Y  KD+     +N  ++   S L   
Sbjct: 129 DLKIE-LDKLEINDMTNREAVVARKYFEKLFGNKYSRKDFT---PMNAALNYGYSILLSA 184

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKF 225
               I++AGY   +G  H  +   F +  D+ +  + 
Sbjct: 185 VNKEIVSAGYVTYLGIHHQSQENMFNFGSDLMESFRP 221


>UniRef50_Q1CW50 CRISPR-associated fusion protein Cas4/Cas1 n=5 Tax=Bacteria
           RepID=Q1CW50_MYXXD
          Length = 568

 Score = 58.1 bits (139), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 47/264 (17%), Positives = 80/264 (30%), Gaps = 44/264 (16%)

Query: 24  QIDVIDGAFVLI--DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
           ++       V+   +  G  +  P   V+ ++     +VS  A+    +    + W    
Sbjct: 241 RVGRAAEELVVTPPEGEGAPSRQPGRMVSALIAHGAVQVSAQALAYCVENDIGVHWFTSG 300

Query: 82  GVRVYASGQPGGARSDKLL-----YQAKLALDEDLRLKVVRKMFELRF------GEPA-- 128
           G  +   G   G    +L       QA + L    RL   +   +LRF      G+    
Sbjct: 301 GRYLGGLGGGAGNVHRRLRQFEALRQASVCLGLARRLVAAKLEGQLRFLLRASRGDSESR 360

Query: 129 -----------------PARRSVEQLRGIEGSRVRATYALLAK------QYGVTWNGRRY 165
                                S+E L G+EG+     +  L           + + GR  
Sbjct: 361 QVLASAVRDLRALLPKCEEAPSLEVLLGLEGAGAARYFGALPYLQGEDVDTRLRFEGRNR 420

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIADII 223
            P      D  N  +      ++   EAAI A G   A GF H   G       D+ ++ 
Sbjct: 421 RPPR----DRFNAVLGFLFGLVHREVEAAIRAVGLDVAFGFYHQPRGTAGPLGLDVMELF 476

Query: 224 KFDTVVPKAFEIARRNPGEPDREV 247
           +             R   + D + 
Sbjct: 477 RVPLADMPLVASVNRRAWDADADF 500


>UniRef50_Q03KT5 CRISPR-associated protein, Cas1 family n=5 Tax=Streptococcus
           RepID=Q03KT5_STRTD
          Length = 334

 Score = 58.1 bits (139), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 40/251 (15%), Positives = 83/251 (33%), Gaps = 44/251 (17%)

Query: 15  VSMIFLQYGQ--IDVIDGAFVLI-DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +S ++ Q     + + +   ++  D   I   + +  V  ++L    +++   ++  ++ 
Sbjct: 1   MSDLYSQRSNYYLSLSEQRIIIKNDNKEIVKEVSISLVDNVLLFGNAQLTTQLIKALSKN 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSD--KLLYQAKLALDEDLRLKVVRKM---------- 119
              + +    G   + S      + +  K   QAK   +ED RL+V R +          
Sbjct: 61  KVNVYYFSNVG--QFISSIETHRQDEFQKQELQAKAYFEEDFRLEVARSIATTKVRHQIA 118

Query: 120 ---------------FELRFGE---PAPARRSVEQLRGIEGSRVRAT--YALLAKQYGVT 159
                          +  RF +         S+ ++ G EG   ++   Y  L       
Sbjct: 119 LLREFDTDGLLDTSDYS-RFEDSVNDIQKAYSITEIMGYEGRLAKSYFYYLNLLVPDDFH 177

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVY 217
           +NGR          D  N  ++   S LY      I   G +   G +H       +   
Sbjct: 178 FNGRSRR----TAEDCFNSALNFGYSILYSCLMGLIKKNGLSLGFGVIHKHHQHHATLAS 233

Query: 218 DIADIIKFDTV 228
           D+ +  +   V
Sbjct: 234 DLMEEWRPIIV 244


>UniRef50_Q5X8T5 Putative uncharacterized protein n=1 Tax=Legionella pneumophila
           str. Paris RepID=Q5X8T5_LEGPA
          Length = 330

 Score = 57.7 bits (138), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 29/113 (25%), Positives = 43/113 (38%), Gaps = 8/113 (7%)

Query: 136 QLRGIEGSRVRATYALLAKQYGV--TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEA 193
            L G EGS  R  +  + +   V   + GRR         D  N  ++ A S L      
Sbjct: 164 TLLGFEGSAARIYWETVKEVNLVCSDFEGRRPRVNK----DITNSMLNYAYSILSSWVWQ 219

Query: 194 AILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           AI  AG     G +HT KP   S V D+ +  +        F++  R   + +
Sbjct: 220 AITNAGLELYAGILHTSKPGKPSLVLDLMEEFRPWCADRIIFKLHARAQKQNE 272


>UniRef50_A4FJX8 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Saccharopolyspora
           erythraea NRRL 2338 RepID=A4FJX8_SACEN
          Length = 549

 Score = 57.3 bits (137), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 41/226 (18%), Positives = 65/226 (28%), Gaps = 45/226 (19%)

Query: 55  EPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLK 114
            P  +V+  AV   A+ G+ +VW    G          G   +    Q       +  L 
Sbjct: 261 GP-VQVTSQAVHALAEQGSPVVWTSTTGRLKSVDIPTVGKHVELRRRQFT--ATPNTALD 317

Query: 115 VVRKMFE----------LRFGEPAPARR---------------SVEQLRGIEGSRVRATY 149
             R++             R                        +   L GIEG+  R  +
Sbjct: 318 FARRIVGGKIRNARTLLRRNPHVEEPDLLNRLDADAVRAERAPTRSTLLGIEGAAARTYF 377

Query: 150 ALLAKQYGVTWN---------GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGY 200
           A L + +              GR   P      D ++  +S     L      A  A G 
Sbjct: 378 AGLVETFRTDHRLPGPAFDTMGRTRRPPR----DAVSCLLSFLYCLLIKDITTACYALGL 433

Query: 201 APAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            P  GF H    G+P +   D+A+  +       A  +      +P
Sbjct: 434 DPYFGFYHQPRHGRP-ALTLDLAEEFRPLIADSTALTLINNLQADP 478


>UniRef50_B3EG05 CRISPR-associated protein Cas1 n=11 Tax=Bacteria RepID=B3EG05_CHLL2
          Length = 384

 Score = 56.9 bits (136), Expect = 8e-07,   Method: Composition-based stats.
 Identities = 22/120 (18%), Positives = 45/120 (37%), Gaps = 11/120 (9%)

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYG-----VTWNGRRYDPKDWEKGDTINQCISAAT 184
           A + +  L G+EG+  +  Y +  +         +++ R   P D    + +N  +S   
Sbjct: 197 AAQDIPSLMGVEGNIRKVYYQVWQQLLRSADPAFSFSERVKRPPD----NAVNALVSFGN 252

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           S +Y      I      P + F+H       S   D+A++ K   +    F++      +
Sbjct: 253 SLMYSACLTEIYRTQLNPTVSFLHEPSERRFSLALDMAEVFKPMFIDRLIFKLVNTRAIQ 312


>UniRef50_B8GLF6 CRISPR-associated Cas1/Cas4 family protein n=1 Tax=Thioalkalivibrio
           sp. HL-EbGR7 RepID=B8GLF6_THISH
          Length = 570

 Score = 56.9 bits (136), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 24/126 (19%), Positives = 44/126 (34%), Gaps = 17/126 (13%)

Query: 130 ARRSVEQLRGIEGSRVRATYALLAK---------QYGVTWNGRRYDPKDWEKGDTINQCI 180
              ++++L GIEG+     +   A+         +    +  R   P      D +N  +
Sbjct: 379 RASNLQELLGIEGAAASRYFGAFARLLKHSDAGPELTFDFTTRNRRPP----TDPVNALL 434

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFEIAR 237
           S A + L     A++ A G  P  GF H    G+P +   D+ +  +         +   
Sbjct: 435 SYAYALLTRSWTASLSAVGLDPYRGFYHQPRYGRP-ALALDMMEPFRPLIADSSVIQAIN 493

Query: 238 RNPGEP 243
                P
Sbjct: 494 NGEVRP 499


>UniRef50_Q8F874 Putative uncharacterized protein n=1 Tax=Leptospira interrogans
           RepID=Q8F874_LEPIN
          Length = 254

 Score = 56.6 bits (135), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 27/148 (18%), Positives = 52/148 (35%), Gaps = 8/148 (5%)

Query: 128 APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI---NQCISAAT 184
                S+E +RG EG+  +  +++    Y +      +      +       N  +S   
Sbjct: 65  LEKAESIESIRGYEGASAKTYFSVF--DYCIIQQKEDFQFHKRTRRPPRSRTNALLSFLY 122

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           S L     A   A G  P IGF+H  +P   S   D+ +  +   +    F +  R   +
Sbjct: 123 SLLTNDCIAVCQAVGLDPYIGFLHDERPGRPSLALDMMEEFRP-FIDRLVFTLINRKQIQ 181

Query: 243 PDREVRLACRDIFRSSKTLAKLIPLIED 270
               +       F +  +  +LI   ++
Sbjct: 182 VSDFLEKPGSVFFINDDSRKELIKSYQE 209


>UniRef50_A1RZT8 CRISPR-associated protein Cas1 n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RZT8_THEPD
          Length = 327

 Score = 56.6 bits (135), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 9/91 (9%)

Query: 150 ALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
             L ++YG  + GR+         D +N+ ISA  + LY ++  A++AAG  P  GF+H 
Sbjct: 170 RELRERYG--FAGRK-----PGHPDPLNKAISAMYAVLYTLSTKALVAAGLDPTYGFLHR 222

Query: 210 GK-PLSFVYDIADIIKFDTVVPKAFEIARRN 239
            +  +   +D A+  K    V  A ++    
Sbjct: 223 TQYSVPLAFDYAEAFKP-LAVEAALDLVNEE 252


>UniRef50_A7I668 CRISPR-associated protein Cas1 n=1 Tax=Candidatus Methanoregula
           boonei 6A8 RepID=A7I668_METB6
          Length = 310

 Score = 56.6 bits (135), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 24/140 (17%), Positives = 54/140 (38%), Gaps = 5/140 (3%)

Query: 133 SVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTE 192
            ++++R +        Y +L++     ++ RR   +   + D IN  +S   + L+G   
Sbjct: 150 KLDEIRRLSDLTANMYYEILSRDIPREFDFRRRTVR--PQCDPINAMLSFGYAMLFGNCC 207

Query: 193 AAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR--NPGEPDREVRLA 250
             ++ A   P +G ++ G   + V D+    K   +    + IAR   N G+ +      
Sbjct: 208 VPVIGARLDPDLGILYEGS-GALVQDLMASFKAQMIDGVIWSIARDSLNVGDFEITSNRC 266

Query: 251 CRDIFRSSKTLAKLIPLIED 270
                     ++     I++
Sbjct: 267 ILSDNLIQNLMSSFRKSIDN 286


>UniRef50_D0LSW9 CRISPR-associated protein Cas1 n=1 Tax=Haliangium ochraceum DSM
           14365 RepID=D0LSW9_HALO1
          Length = 594

 Score = 56.2 bits (134), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 46/260 (17%), Positives = 85/260 (32%), Gaps = 38/260 (14%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTH-IPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVG 79
           ++G +     A ++I + G     + +  V+ I L     ++  A++ A   G  +    
Sbjct: 273 EHGAVVSKRAAELVIKRKGSELERVRIKDVSRINLHGSAHITLPALQTALGNGIPVGLFT 332

Query: 80  EAGVRVYASGQPGGARSDKLLYQAKLAL--DEDLRLKVVRKMFELRFGEPAP-------- 129
             G   Y     G    + LL QA+ A   DE   L++ +++   +              
Sbjct: 333 YGG--WYYGRAQGHDHKNVLLRQAQFASAQDEGRCLRIAQRLVHAKIKNSRVMLRRNSRA 390

Query: 130 -----------------ARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNGRRYDPKDW 170
                               S   L GIEGS  R  +   +      V ++    + +  
Sbjct: 391 LDRRILDDLSGHARRARQADSQATLLGIEGSAARLYFQNFSGMLRQDVPFSFDSRNRRPP 450

Query: 171 EKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKFDT 227
              D +N  +S + + L     A +   G+ P  GF H    G+P S   D+ +  +   
Sbjct: 451 R--DPVNALLSFSYALLTAEWTATLSTVGFDPYQGFYHQPRYGRP-SLALDLMEEFRPLI 507

Query: 228 VVPKAFEIARRNPGEPDREV 247
                         + D  V
Sbjct: 508 ADSVVIGAINNGVLDEDDFV 527


>UniRef50_D0W646 CRISPR-associated protein Cas1 n=1 Tax=Neisseria cinerea ATCC 14685
           RepID=D0W646_NEICI
          Length = 325

 Score = 55.8 bits (133), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 35/226 (15%), Positives = 73/226 (32%), Gaps = 39/226 (17%)

Query: 18  IFLQYGQI-DVIDGAFVLIDKTGIRTH-IPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++    +    DG  ++  + G RT  IP+  + C+ +     +S   +    +    +
Sbjct: 4   LYIDRKNLTLRADGDSLVCYENGERTATIPLKVLQCVCIRGDLTLSAKVLGKLGEADIGV 63

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRK------------MFEL- 122
           + +     R             + + Q   + D+   L   R             + ++ 
Sbjct: 64  LVLNGRLKRPALMLPNLKLDGSRRVAQYAFSQDKAACLAAARNTVSAKLSAQQQHLQQMM 123

Query: 123 ------------------RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVT--WNG 162
                             R  +  P    + +LRGIEG+     +   A     T  + G
Sbjct: 124 PSDGTAADCLNKHIKAISRLADTVPDCNGIARLRGIEGAAAAQYFGAWAAVLPETLHFTG 183

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH 208
           R   P      D +N  +S   + ++      +  +G  P IG+ H
Sbjct: 184 RNRRPPR----DPVNAALSLTYTLMHFEIVKHLHLSGLDPFIGYYH 225


>UniRef50_B7KM77 CRISPR-associated protein Cas1 n=1 Tax=Cyanothece sp. PCC 7424
           RepID=B7KM77_CYAP7
          Length = 334

 Score = 55.4 bits (132), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 25/163 (15%), Positives = 56/163 (34%), Gaps = 14/163 (8%)

Query: 128 APARRSVEQLRGIEGSRVRATYALLAK---QYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
             +  +++QLRG EG      +    +       +++ R   P      D +N  +S   
Sbjct: 145 LESVDNLDQLRGYEGIAAARYFPAFGQLITNAAFSFSLRNRQPP----TDPVNSLLSFGY 200

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGE 242
           + L+    + I++ G +P  G  H G+       +D+ +  +   V      +       
Sbjct: 201 TLLFNNVLSLIISEGLSPYFGNFHYGERDKPYLAFDLMEEFRAIIVDGMVLRVINNGLLT 260

Query: 243 PDREVRLACRDIFRSSKTLAKLI-----PLIEDVLAAGEIQPP 280
                 +A       +    ++        I  +++  +IQ P
Sbjct: 261 LKDFEPVASNGGVYLTDKGRRIFLKEFESRINKLISHPDIQSP 303


>UniRef50_B1GZM4 CRISPR-associated protein Cas1 n=1 Tax=uncultured Termite group 1
           bacterium phylotype Rs-D17 RepID=B1GZM4_UNCTG
          Length = 298

 Score = 55.4 bits (132), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 32/231 (13%), Positives = 78/231 (33%), Gaps = 10/231 (4%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTLLVWVGEA 81
             + V +       +      IP+  ++ I+LE     ++ A +   +Q   ++     +
Sbjct: 12  CSLSVKNSQLYCRFQDSTVHDIPIEDISVIVLESNRINLTSALISECSQSNIVIFSCDSS 71

Query: 82  GVRV--YASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRG 139
            +    Y         +     Q K       R+       ++        + S     G
Sbjct: 72  HIPCGIYVPFNQHSRFTQTANSQVKWDTAFKNRIWQKIVKQKICNQAEIIKKYSFANYVG 131

Query: 140 IEGS--RVRATYAL--LAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAI 195
           ++G+  RV++       A    + W     + +  +  D  N  ++   + + GV   ++
Sbjct: 132 LKGTCDRVQSGDKTNCEAFAAKIYWESIFENFQRNKNSDIRNSALNYGYAIVRGVVARSL 191

Query: 196 LAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPD 244
            ++G+    G  H+    +F    DI +  +   V   A +I + +    +
Sbjct: 192 ASSGFITCFGVHHSNDLNAFNLADDIIEPFRP-FVDDIAIDIFKNSETSKE 241


>UniRef50_UPI0000F51762 hypothetical protein Faci_00015 n=1 Tax=Ferroplasma acidarmanus
           fer1 RepID=UPI0000F51762
          Length = 328

 Score = 55.4 bits (132), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 41/234 (17%), Positives = 75/234 (32%), Gaps = 35/234 (14%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           + V  G  ++ +  G +  IPV +V  +       +S   V + +++G  + +    G  
Sbjct: 14  VYVDGGTIIIENSIG-KNAIPVENVRSVYAHKPVSISSGVVSIISKLGIPIHFFNWYG-- 70

Query: 85  VYAS---GQPGGARSDKLLYQAKLALDEDLRLKVVRKM-------FELRFGEPAPAR--- 131
            Y +    +      D ++ QA+  LD   R+ + +         F     E        
Sbjct: 71  NYEATLWPKSKDISGDVIIKQAQKYLDIHERINIAKSFVSGALHNFNRILSEYDTETVKK 130

Query: 132 ---------------RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
                            + ++ GIEG    + +  +     +    R         G+  
Sbjct: 131 SREDIKSNIGNLTNAMDITEIMGIEGRSHNSYFKAMDSV--IPEKFRINKRIRRPPGNMG 188

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTV 228
           N  IS   S +Y      I      P I ++H       S   DIA+I K    
Sbjct: 189 NALISFGNSLVYASVLTEIYFTHLNPTISYLHEPSERRFSLSLDIAEIFKPIIS 242


>UniRef50_D0MJ58 CRISPR-associated protein Cas1 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MJ58_RHOM4
          Length = 360

 Score = 54.6 bits (130), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 50/281 (17%), Positives = 85/281 (30%), Gaps = 52/281 (18%)

Query: 10  PLKDRVSMIFLQYG---QI--DVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
            L+ R + +F +     +I  D  +        TG  T  PV  V  +       ++   
Sbjct: 12  RLRRRQNTLFFEKAAGERIPDDQDETGVPSGTPTGESTPFPVEQVESLYFFGEVDLNSKL 71

Query: 65  VRLAAQVGTLLVWVGEAGVRVYAS---GQPGGARSDKLLYQAKLALDEDLRLKVVR---- 117
           +   A+      +    G   Y      +         + Q    +    R  + R    
Sbjct: 72  LTFLARHDIPAHFYDYYG--NYTGTYIPRDYLHSGRLRIEQVLHYVRPKRRRYLARAIVE 129

Query: 118 ----------KMFELRFGEPA-----PARRSVEQ-------------LRGIEGSRVRATY 149
                     + +  R           A  ++EQ             L GIEG R R  Y
Sbjct: 130 AATYNLLRVLRYYVNRLEGERREAVAEAIATIEQERTQLRSAEKIPELMGIEG-RSREAY 188

Query: 150 -----ALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAI 204
                ++LA   G  +   + + +     + IN  IS   S  Y  T   I      P I
Sbjct: 189 YSAWPSILADGPGEAFVFEKRERRPP--SNEINALISFGNSLCYTTTIRQIHRTALDPTI 246

Query: 205 GFVHT--GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            ++H    +  S   D+++I K   V    F + +     P
Sbjct: 247 SYLHEPGARRFSLALDLSEIFKPILVDRAIFRLVKTGEITP 287


>UniRef50_C3WD45 CRISPR-associated protein cas1 n=1 Tax=Fusobacterium mortiferum
           ATCC 9817 RepID=C3WD45_FUSMR
          Length = 327

 Score = 54.6 bits (130), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 18/92 (19%), Positives = 34/92 (36%), Gaps = 4/92 (4%)

Query: 135 EQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAA 194
            ++ G EG      Y  + K     W+      +     +  N  ++ A   LY   E  
Sbjct: 157 NRVMGYEGRSSILYYEEIKKFLPENWSFT--KRETQGAKEPYNIVLNYAFGILYFKLERY 214

Query: 195 ILAAGYAPAIGFVHT--GKPLSFVYDIADIIK 224
           +  AG    +G +H+   K  S ++D  +  +
Sbjct: 215 LTLAGLDIQLGIIHSNNNKSNSLIFDFIEPFR 246


>UniRef50_A8REI1 Putative uncharacterized protein n=2 Tax=unclassified
           Erysipelotrichaceae RepID=A8REI1_9FIRM
          Length = 300

 Score = 54.6 bits (130), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 31/241 (12%), Positives = 84/241 (34%), Gaps = 53/241 (21%)

Query: 17  MIFLQ---YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVG 72
           +++++   + Q+ + +   + ++ +      P+  +  ++++   + ++   V    +  
Sbjct: 5   VLYIENQYHLQLYLDN---LKVETSQGDIQFPISDIQILVIDHYRSTLTVPLVNKLTENN 61

Query: 73  TLLVWVGEAGVR-VYASGQPGG-ARSDKLLYQAKLALDEDLRL----------------- 113
             ++  G   +   Y     G  A+S  ++ Q     +E  ++                 
Sbjct: 62  VCVIICGIDHLPKSYILPMNGHFAQSGNIMKQIT-WSNEIKQILHQQIVKAKIFNQIEIL 120

Query: 114 -------KVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYD 166
                  +V++K++E  +        +       EG   +  +  +   +G  +      
Sbjct: 121 KTNQCKYEVIKKLYEF-YDTVDLGDAT-----NREGLAAKMYFREM---FGNDFIRFE-- 169

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIK 224
                  D IN  ++   S    +  + I+  GY P +G  H GK   F    DI ++ +
Sbjct: 170 ------DDVINAGLNYGYSIFRSLISSIIVGKGYLPNLGIFHKGKTNMFNLSDDIIEVFR 223

Query: 225 F 225
            
Sbjct: 224 P 224


>UniRef50_B3W9S5 CRISPR-associated protein n=4 Tax=Lactobacillus RepID=B3W9S5_LACCB
          Length = 301

 Score = 54.6 bits (130), Expect = 4e-06,   Method: Composition-based stats.
 Identities = 36/238 (15%), Positives = 82/238 (34%), Gaps = 45/238 (18%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTR--VSHAAVRLAAQVGT 73
           S+I  Q+ ++   +   V+    G   ++P+  +  ++    TR  +S  A+   A+   
Sbjct: 5   SLIVTQHCKVTTKNRTLVVQT-DGEVNNVPIEDINQVVFTT-TRALLSADAITTLAEANA 62

Query: 74  LLVWVGEAGVR------VYASGQPGGARSDKLLYQA----KLALDEDLRLKVVRKMFELR 123
            +++ G  G        +Y+       ++D +  Q      L  +   ++   +   + +
Sbjct: 63  KVIFSGRDGQPVTETTNLYS----DRRKADLVRLQVNWPKSLVENLWTKIVAAKVSNQAQ 118

Query: 124 ------FGEP----APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKG 173
                 F             +      E +  R  + L+   +G           D+ + 
Sbjct: 119 VTKLCGFDNQSLLDDLDTLEINDRSNREATAARKYFKLI---FG----------DDFSRS 165

Query: 174 D--TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDT 227
           D    N  ++   S L   T  AI++AG+   IG  H+      +   D+ +  +   
Sbjct: 166 DICATNAALNYGYSILLSTTNRAIVSAGHITEIGMHHSSVANQYNLGSDLMEPFRPAI 223


>UniRef50_Q2FPW6 CRISPR-associated protein Cas1 n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FPW6_METHJ
          Length = 303

 Score = 54.6 bits (130), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 43/269 (15%), Positives = 83/269 (30%), Gaps = 35/269 (13%)

Query: 26  DVIDGAFVL-IDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
            +      + I   G  T IP+  ++  +L  G  +  + +    + G  + +    G  
Sbjct: 7   HIKSNRTEITIQHKGKITDIPIKDLSHFLLIGGHTIQTSTITSLVKEGVFISFCESDGEP 66

Query: 85  V-YASGQPGGARSDKLLYQ--------AKLALDEDLRLKV-VRKMFELRFG--------- 125
           V Y S        +    Q        A    +E ++ ++   + +    G         
Sbjct: 67  VGYISPYDYSLFKEIQNLQKTAAPYSYALACANESIKSRILAIEKYAEEIGPEILFSGEL 126

Query: 126 -------EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVT--WNGRRYDPKDWEKGDTI 176
                  +       +E+LR IE       Y +L +    T  +  R   P      D +
Sbjct: 127 DILTGYAKELENMVLIEELRRIEQLVRDMYYEILGRLISPTYLFKRRTSRP----YLDPV 182

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIA 236
           N   S     L      A++     P  G+++ G   + V D+ +  K   +   A    
Sbjct: 183 NAIFSFGYGMLSSACTRAVIGGHLDPGHGYLNRGNQ-ALVQDLMNCWKPKMIDNHAIGFL 241

Query: 237 RRNPGEPDREVRLACRDIFRSSKTLAKLI 265
           R      +   R   R      + + +LI
Sbjct: 242 RSGRLHQNGYERTKDR-CILHDEVIEELI 269


>UniRef50_A1WH94 CRISPR-associated protein, Cas1 family n=5 Tax=Proteobacteria
           RepID=A1WH94_VEREI
          Length = 309

 Score = 54.2 bits (129), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 44/262 (16%), Positives = 85/262 (32%), Gaps = 39/262 (14%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTH---IPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLV 76
               + V  G  V+ D  G R     +P+  +A ++    G   ++  +   A+ G   V
Sbjct: 11  DRRHLFVNRGFMVIKDTEGERKELGQVPLDDIAAVIANAHGLTYTNNLLVALAERGAPFV 70

Query: 77  WVGEAGVRVYASGQPGGAR-----SDKLLYQAKLALDEDLRLKVVR-----KMFELRFGE 126
             G       A G           + ++  Q    L    RL         +        
Sbjct: 71  LCGPN---HNAVGMLLPLDGHHVQAKRIEAQIAAGLPMHKRLWAAVVKSKLEQQAAALEA 127

Query: 127 PAPARRSVEQL---------RGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTIN 177
            A     ++ L           IEG   R  + LL   +G  +          + GD +N
Sbjct: 128 VAAPTAPLQALVAKVRSGDPENIEGQGARRYWGLL---FGAEFRR-------DQSGDGLN 177

Query: 178 QCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEI 235
             ++   + +      A++AAG  P+IG  H+    +   V D+ +  +   V  K +++
Sbjct: 178 ALLNYGYTIVRSACARAVVAAGLHPSIGLHHSNDANAMRLVDDLMEPFRP-IVDLKVWQL 236

Query: 236 ARRNPGEPDREVRLACRDIFRS 257
            +        + + A   +   
Sbjct: 237 HKAGESHVTPDTKRALVRVLYD 258


>UniRef50_A3DLB7 CRISPR-associated protein, Cas1 family n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DLB7_STAMF
          Length = 341

 Score = 54.2 bits (129), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 46/273 (16%), Positives = 84/273 (30%), Gaps = 50/273 (18%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           +    G  V++   G R   PV  V  +++     +S   ++L A  G  ++     G  
Sbjct: 19  LRKKHGRIVVVS-RGGREEFPVRRVREVIISGKAGISTELLKLLADSGIDVLVTSYTGRP 77

Query: 85  --VYASGQPGGARSDKLLYQAKLALDEDLRLKVV-------------RKMF---ELRFGE 126
             ++   + G       + Q +   D                      K +        +
Sbjct: 78  VALFVHARSG-GSVRNRIEQYRSLEDGRACKAAAMIISGKLSNQVSNLKYYSKPRKNISQ 136

Query: 127 P--------APARRSVEQLRGIE----GSRVRATYALLAKQYGVTWNG-----------R 163
                       ++  E+LR IE    G       ++ A+     W+G            
Sbjct: 137 ESKILYEKAEEIKKLREKLRDIETSDLGKCRENIMSIEAQAANTYWDGMRIVLGKYGFKE 196

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKP--LSFVYDIAD 221
           R      ++ D +N C++   + L G     +L     P  GF+H  +P  LS VYD+ +
Sbjct: 197 RVKRGRGKEVDPVNLCLNIIYNKLAGTVWKYVLRFSLDPFQGFLHARRPGKLSLVYDLME 256

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDI 254
             +     P A     R     D+         
Sbjct: 257 PFR-----PIADRFIARFLYRLDQGFLRRASGA 284


>UniRef50_A7BYC5 Protein containing DUF48 n=1 Tax=Beggiatoa sp. PS
           RepID=A7BYC5_9GAMM
          Length = 322

 Score = 53.9 bits (128), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 45/262 (17%), Positives = 84/262 (32%), Gaps = 44/262 (16%)

Query: 18  IFLQY-GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
           +F+     +   +     +   G     P+  +  ++L   + ++   + L  Q G  L 
Sbjct: 4   LFISRDATLKRRENTLA-VTVGGKTKPFPIEKIRHLVLLGESSLNTKLLTLCGQNGVRLS 62

Query: 77  WVGEAGVRVYASGQPG---GARSDKLLYQAKLALDEDLRLKVVR--------------KM 119
                G   +                L QAKL LD++ R+ + R                
Sbjct: 63  IFDYYG--YFKGAFEPIEQNGSGRVKLAQAKLILDQEQRMAIAREIVRGAAHNMRANLAY 120

Query: 120 FELRFGEPAPARRSVE---------------QLRGIEGSRVRATYALLAK-QYGVTWNGR 163
           ++ R G  A ++ + E               +L G EG   +  +A  A     + +  R
Sbjct: 121 YQYR-GNKALSKSTQEITKLMDRLHFAKDSDELMGFEGQITQTYFAAWALIDQRLDFLPR 179

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIAD 221
              P +    + IN  IS      Y VT            + F+HT      S   D+++
Sbjct: 180 VRRPPN----NPINCLISFINQLTYTVTRHEAFKTHLEETLSFLHTPSTGRSSLSLDLSE 235

Query: 222 IIKFDTVVPKAFEIARRNPGEP 243
             K         ++ R+N  + 
Sbjct: 236 PFKPVLSHGLIIKMVRKNMVDD 257


>UniRef50_B5YJS2 Crispr-associated protein Cas1 n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YJS2_THEYD
          Length = 318

 Score = 53.9 bits (128), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 41/253 (16%), Positives = 84/253 (33%), Gaps = 47/253 (18%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +F+     +I V   +     K      +P+  +  +++    ++  + +      G
Sbjct: 1   MSTVFIDRKDIEIRVDGNSISFYAKGKKDGSLPLSPLKRVVIVGNVKIETSVLYKLVNHG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLY--------------------QAKLALDED-- 110
             ++++   G   Y+    G   ++ LL                     + K+    D  
Sbjct: 61  ITVLFL--TGKLKYSGILNGPLHNNGLLRVKQYQKSLSGFSLKFAKELIKRKIVSQRDFL 118

Query: 111 ---LRLKVVRKMFELR--------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--G 157
                +K    M   R                 S++ LRGIEG+     +   +K +   
Sbjct: 119 SEIREIKKALAMQADRAIEILNKAISNIEVTPISIDSLRGIEGAASSIYFITYSKIFPNS 178

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLS 214
           + +  R   P      D +N  +S   + L+      I   G  P IGF H    G+  S
Sbjct: 179 LKFVRRIKRPPK----DPVNAMLSLCYTLLHYEIVREIQLIGLDPTIGFYHQFEYGRE-S 233

Query: 215 FVYDIADIIKFDT 227
              D+ ++ + + 
Sbjct: 234 LACDLVELFRVNV 246


>UniRef50_C0A724 CRISPR-associated Cas1/Cas4 family protein n=1 Tax=Opitutaceae
           bacterium TAV2 RepID=C0A724_9BACT
          Length = 691

 Score = 53.9 bits (128), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 47/303 (15%), Positives = 86/303 (28%), Gaps = 85/303 (28%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV- 83
           +        + +K  +   I +  ++ + +     +S A +   A+    + +   AG  
Sbjct: 329 LLKKSELIQIREKGELVNEIRIKDLSHVAIFGSATISTALLNELAERDIAVSYFSSAGTL 388

Query: 84  RVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------LRFGEPAPARR- 132
           R Y  G        + + Q + A      L++ R   +          +R     PA   
Sbjct: 389 RAYTRGPSLKNVFTR-IAQFRAADTPATALRIARLFVQGKIRNQRTLIMRNHAMPPASTL 447

Query: 133 --------------SVEQLRGIEGSRVRATYALLA------------------------- 153
                         S+E+L GIEGS   A +   +                         
Sbjct: 448 GRLQHAITAAANTESIEELLGIEGSAALAYFQEFSGMIKTTGDDILDAIAEGREPEPGSL 507

Query: 154 -------------------------KQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLY 188
                                    + +   +  R   P      D +N  +S A S L 
Sbjct: 508 SDTTQAPDITTGKKRRSGKRDTPGQEFFSFDFTRRNRRPPR----DAVNALLSLAYSILA 563

Query: 189 GVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDR 245
               +A  A G+ P +GF H    G+P +   D+ +  +          +       P  
Sbjct: 564 KDCTSAAHAVGFDPYVGFYHQPRFGRP-ALALDLMEEFRPLVADSVVLTLINTRMISPTD 622

Query: 246 EVR 248
            VR
Sbjct: 623 FVR 625


>UniRef50_C6MJ62 CRISPR-associated protein Cas1 n=5 Tax=Nitrosomonas sp. AL212
           RepID=C6MJ62_9PROT
          Length = 430

 Score = 53.5 bits (127), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 22/110 (20%), Positives = 43/110 (39%), Gaps = 15/110 (13%)

Query: 133 SVEQLRGIEGSRVRATYALLA--------KQYGVTWNGRRYDP-----KDWEKGDTINQC 179
           ++E++R IE       ++           K   + W G          K ++    +N  
Sbjct: 251 TLEEMRLIEARAAIIYWSTWNNCVIKWKEKDVPIEWRGFSQRASGISGKGYKATHPVNAI 310

Query: 180 ISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDT 227
           ++ A + L G  E A+   G   A+G +H  +    S VYD+ + ++   
Sbjct: 311 LNYAYAILAGQVERALQIVGLDVAVGSLHADQDGRASLVYDLMEPLRPVI 360


>UniRef50_Q7MTH7 CRISPR-associated protein Cas1 n=3 Tax=Porphyromonas gingivalis
            RepID=Q7MTH7_PORGI
          Length = 1031

 Score = 53.1 bits (126), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 37/284 (13%), Positives = 79/284 (27%), Gaps = 61/284 (21%)

Query: 45   PVGSVACI-MLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQA 103
            P   +  I ++  G  +S    +   +    +++    G    +           +  Q 
Sbjct: 729  PAAQIEQISIISDGVSLSSNVTKYCRKKNIRVIFYNATGQAYASLNGMNTILPSVMEAQM 788

Query: 104  KL----------------ALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEG----- 142
            +L                  ++   L+   K +        P   ++ +L+ +EG     
Sbjct: 789  RLSEEKKREFILTLIKNKVRNQGKLLRYYHKYYRHDKELKEPLSNAIAELKQLEGIPIAE 848

Query: 143  ---------------SRVRATY----ALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
                           +R    Y    ALL  + G  + GR +          +NQ ++  
Sbjct: 849  GSSLADFRQHAMLHEARCAQVYWRAFALLVHRSGHEFEGREHK----GAEGLVNQMLNYG 904

Query: 184  TSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPKAFEIARRNP- 240
             + L       I+     P IG +H+      +  +D+ +  +   V      +  +   
Sbjct: 905  YAILRSYVMKTIVLWQLNPNIGILHSTQDNKPALCFDLMEQYRAFVVDRSILALLAKGED 964

Query: 241  ------GEPDREVRLACRDIFRSS-------KTLAKLIPLIEDV 271
                  G  D   R                 ++  KL   I  +
Sbjct: 965  VGQNSKGLLDMPTRSRIISKINERWFATEYYRSGEKLFSDIMKL 1008


>UniRef50_B5ZLL1 CRISPR-associated protein Cas1 n=2 Tax=Gluconacetobacter
           diazotrophicus PAl 5 RepID=B5ZLL1_GLUDA
          Length = 297

 Score = 53.1 bits (126), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 38/253 (15%), Positives = 81/253 (32%), Gaps = 29/253 (11%)

Query: 30  GAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLVWVGEAGVRVYAS 88
              +++ + G    + V  +AC++L+     ++ + +   A+ G  ++       R + +
Sbjct: 18  NRQLVVAQDGGEVSLAVEDIACLILDTRQVSITGSLLSALAENGVAMIV---PDARHHPA 74

Query: 89  GQPGGARSDKLLYQA-------------KLALDEDLRLKVVRKMFELRFGEPA--PARRS 133
           G                           +L       L V +   +    +    P  ++
Sbjct: 75  GILLPFHQHHAQAHIAHAQISISQPLKKRLW----QTLVVAKIRNQAALLDQLGRPQGQT 130

Query: 134 VEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEA 193
           +  + G   S         A +    W     D     + D  N  ++   + +      
Sbjct: 131 IAAMAGRVASGDPGNVEAQAARAY--WASLFSDFTRANENDRRNALLNYGYAIMRAAIAR 188

Query: 194 AILAAGYAPAIGFVHTGKPLSF--VYDIADIIKFDTVVPKAFEIARRNPGEPDR-EVRLA 250
           A +A G  PA G  H  K  +F  V D+ +  +   V   A + A  + G+    E R  
Sbjct: 189 ACVALGLLPAFGVHHASKTNAFNLVDDLIEPFRP-FVDRMAHDRALEHVGDTLSIEDRRQ 247

Query: 251 CRDIFRSSKTLAK 263
              I   +  + +
Sbjct: 248 MSTILNDNAAIGR 260


>UniRef50_A1BI46 CRISPR-associated protein Cas1 n=2 Tax=Chlorobiaceae
           RepID=A1BI46_CHLPD
          Length = 347

 Score = 52.7 bits (125), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 38/206 (18%), Positives = 71/206 (34%), Gaps = 32/206 (15%)

Query: 91  PGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYA 150
                   L   A+ +  E LR     ++ +L   E      S++ +RG EGS     + 
Sbjct: 122 KLHNSGVLLRRHAESSGSEALR-HAATQLRQLE--EHVDRADSIDAVRGYEGSGAATYFG 178

Query: 151 LLAKQY---GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFV 207
           +    +   G  +  R   P      D +N  +S   S L+    +        P +GF+
Sbjct: 179 VFEDFFDTGGFIFRERVKRPP----TDPVNAMLSFGYSLLFNNIFSMARLHRLHPYVGFL 234

Query: 208 HTGKPL--SFVYDIADIIKF------------DTVVPKAFEIARRNPGEPDREVRLACRD 253
           H  KP   + V D+ +  +               + P+ F +AR + G+P        + 
Sbjct: 235 HADKPAHPALVSDLIEEFRTLVDGLVIALINKRLISPEEFTVARHDDGKP--------KG 286

Query: 254 IFRSSKTLAKLIPLIEDVLAAGEIQP 279
            + S       +   E+++      P
Sbjct: 287 CYLSDGARKTFLREFENLMHRTTTHP 312


>UniRef50_UPI0001BCCAFD hypothetical protein SnoxA4_00467 n=1 Tax=Selenomonas noxia ATCC
           43541 RepID=UPI0001BCCAFD
          Length = 281

 Score = 52.7 bits (125), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 20/123 (16%), Positives = 39/123 (31%), Gaps = 4/123 (3%)

Query: 124 FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
             +  P   +  QL G EG+  +  +  L       +   +   +     D  N  +S  
Sbjct: 88  LSKHIPRCETNTQLMGYEGAIAKVYFRALGLLVPEAFAFVKRSRRPPM--DPFNTMLSFG 145

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPG 241
            + L       +   G  P  GF+H  K    +   D+ +  +   V      +   +  
Sbjct: 146 YTLLMYDLYTVVNNEGLHPYFGFLHALKNRHPALASDLMEEWRPVLVDAMVLSLVHHHEM 205

Query: 242 EPD 244
            P+
Sbjct: 206 RPE 208


>UniRef50_C8W3G7 CRISPR-associated protein Cas1 n=24 Tax=Bacteria RepID=C8W3G7_DESAS
          Length = 335

 Score = 52.3 bits (124), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 44/265 (16%), Positives = 83/265 (31%), Gaps = 45/265 (16%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA- 81
           G +   D +     + G    IP+     +       +S   ++L A+ G ++ + G   
Sbjct: 14  GDLYQKDFSIAFRKEDGNFY-IPIKDTRELYCFNDITLSTKLLQLLAKAGIVVHFFGYYE 72

Query: 82  ---GVRVYASGQPGGARSDKLLYQAKLALDEDLRLK------VVRKMFEL-----RFG-- 125
              G   Y   +         + QA       L++       + +  + +     R G  
Sbjct: 73  NYIGT-FY--PKEQLLSGRLTVAQALAYEQNRLQIAGQIIKGIAKNTYFVLYHYYRHGKS 129

Query: 126 ---------EPAPARR-----SVEQLRGIEG---SRVRATYALLAKQYGVTWNGRRYDPK 168
                        +R      +++QL  IEG   +R   ++ +   +     N R   P 
Sbjct: 130 ELKDFLDWLRKDVSRLVDSVGNIKQLLRIEGEIWARFYQSFRVFLPE-SFAMNKRVKRPP 188

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFD 226
           D    + IN  IS   + LY  T   I        I F+H       S   D++++ K  
Sbjct: 189 D----NPINALISFGNTLLYTKTITQIFHTHLNQTISFLHEPAERRFSLSLDLSEVFKPV 244

Query: 227 TVVPKAFEIARRNPGEPDREVRLAC 251
            V    F+         ++      
Sbjct: 245 LVCKTIFDCVNNRKIMVEKHFDKKL 269


>UniRef50_C5EZ73 Crispr-protein cas1 n=1 Tax=Helicobacter pullorum MIT 98-5489
           RepID=C5EZ73_9HELI
          Length = 230

 Score = 51.9 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 10/88 (11%)

Query: 131 RRSVEQLRGIEG-SRVR--ATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCL 187
            ++++QL GIEG   V    T+  +AK        R +        D +N   + A + L
Sbjct: 145 AKNIKQLMGIEGKCAVLYWNTFRHMAK-------FRGFHRIKRNAKDVLNASFNYAYAIL 197

Query: 188 YGVTEAAILAAGYAPAIGFVHTGKPLSF 215
           +G  +++I+ A   P I F+H     S 
Sbjct: 198 HGSIQSSIIKAELNPHISFLHIQNSKSL 225


>UniRef50_A7HP88 CRISPR-associated protein Cas1 n=1 Tax=Parvibaculum lavamentivorans
           DS-1 RepID=A7HP88_PARL1
          Length = 311

 Score = 51.9 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 39/258 (15%), Positives = 93/258 (36%), Gaps = 28/258 (10%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLVWVGEAG 82
           ++ V +   V+      +  +P+  +  ++++      + A      + G  ++  G   
Sbjct: 14  RLSVANKQLVIERPDLPKATLPIEDLGVVIVDDLRATYTQAVFIELLEAGATVMVTGRDH 73

Query: 83  VRVYASGQPGGARSDKLL---YQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRG 139
           +    +G      +  +    ++A++   E  + +  + +   +  +       +    G
Sbjct: 74  LP---AGMMLPLDAHHIQTERHRAQVEASEPTKKRAWQALIRSKIAQQ---GIVLAHFTG 127

Query: 140 IEG------SRVRA-----TYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLY 188
             G       RVR+       A  A++Y     G+ +      +G  +N  ++   + + 
Sbjct: 128 EHGGLLPMARRVRSGDPDNLEAQAAQRYWPRLFGKDFRRDRDLEG--VNALLNYGYAVVR 185

Query: 189 GVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDT---VVPKAFEIARRNPGEP 243
             T  A +AAG  P++G  H  +   F    D+ +  +      V   A ++    P   
Sbjct: 186 AATARATVAAGLIPSLGVFHRNRANPFCLADDLLEPYRPYVDWRVRLLANQMGEEAPSLD 245

Query: 244 DREVRLACRDIFRSSKTL 261
           DR+ R A   IF  +  +
Sbjct: 246 DRDTRAALLSIFNETVLV 263


>UniRef50_C7V674 Predicted protein n=2 Tax=Enterococcus faecalis RepID=C7V674_ENTFA
          Length = 304

 Score = 51.9 bits (123), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 40/244 (16%), Positives = 75/244 (30%), Gaps = 33/244 (13%)

Query: 37  KTGIRTHIPVGSV-ACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA--------GVRVY- 86
           K G    IP+  + + I+    T ++   +   AQ     V             G+  Y 
Sbjct: 25  KEGNTYVIPLTDIESVILEGDQTVITTRLLAKFAQHHIDTVICDNTFMPVGVFLGIGQYH 84

Query: 87  -----ASGQPGGARSDKLLYQAKLALDE-DLRLKVVRKMFELRFGEPAPARRSVEQLRG- 139
                A  Q       K +   ++   +   ++ V + +           + S   L G 
Sbjct: 85  RSAKRAIWQSNWTEEHKQVAWCEIVTQKIQNQIAVAKYLGTDSERVEVLEKLSEGILPGD 144

Query: 140 ---IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAIL 196
               EG   +  +  L   YGV +          E+    N C++   + +       ++
Sbjct: 145 TTNREGHVAKVYFHSL---YGVGFTR--------EEECLPNACMNYGYAVIRAQMARCVV 193

Query: 197 AAGYAPAIGFVHTGKPLSF--VYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDI 254
           A G  P +G  H  +  SF  V D+ +  +          I ++N        RL   + 
Sbjct: 194 ALGLLPMLGIFHKNEYNSFNLVDDLMEPFRPLMDWYIHQTILKKNEKYLTYHSRLTLVEF 253

Query: 255 FRSS 258
               
Sbjct: 254 LHQK 257


>UniRef50_Q13CC1 CRISPR-associated protein, Cas1 family n=2 Tax=Rhodopseudomonas
           palustris RepID=Q13CC1_RHOPS
          Length = 299

 Score = 51.5 bits (122), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 48/274 (17%), Positives = 93/274 (33%), Gaps = 39/274 (14%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLE-PGTR 59
           M W  L+             Q  ++ + D     + +      + +  +A I+++ P   
Sbjct: 1   MAWRGLHLT-----------QAARLSLADSQVC-VKQDAGEVRLALEDIAWIVIDTPQAT 48

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGG-----ARSDKLLYQA--------KLA 106
           ++ A +    + G +LV+  E       SG          +      Q         +L 
Sbjct: 49  LTSALMSACMEAGIVLVFTDERHTP---SGMALPFHRHHRQGGIARLQMDAKDGVKKRLW 105

Query: 107 LDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYD 166
               +R K++ +   L   +   A    E  R +E        A  A+ Y   W     D
Sbjct: 106 -QAIIRRKILNQAGSLAVLDRNNAETLREIARHVEPGDPENVEARAARFY---WGRLFED 161

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIK 224
               + GD  N+ ++   + +      A++A+G+ PA G  H G   +F    D+ +  +
Sbjct: 162 FVRDDDGDLRNKMLNYGYAVVRAGVARALVASGFLPAFGLKHDGAANAFNLADDLVEPFR 221

Query: 225 FDTVVPKAFEIAR---RNPGEPDREVRLACRDIF 255
              V   A++         G+   E R A   + 
Sbjct: 222 P-FVDVLAWKTLGDRVDRKGDLTLEDRRAMAGVL 254


>UniRef50_Q6A5T6 Putative uncharacterized protein n=1 Tax=Propionibacterium acnes
          RepID=Q6A5T6_PROAC
          Length = 112

 Score = 51.5 bits (122), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 12/40 (30%), Positives = 20/40 (50%)

Query: 35 IDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
             +G   H+P   +  ++L PGT V+H A+ L  + G  
Sbjct: 5  HQTSGGTVHVPASIIGALLLGPGTNVTHQAMVLLTESGAA 44



 Score = 44.6 bits (104), Expect = 0.004,   Method: Composition-based stats.
 Identities = 14/51 (27%), Positives = 18/51 (35%)

Query: 235 IARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPED 285
            A  +  +     R A RD F  SK L K +  I  +L A          D
Sbjct: 43  AATGDIDDLAGVTRRAMRDAFHESKLLTKCVQDIHVLLDAPGDPDEGYGWD 93


>UniRef50_Q03LF6 CRISPR-associated protein, Cas1 family n=6 Tax=Streptococcus
           RepID=Q03LF6_STRTD
          Length = 303

 Score = 51.2 bits (121), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 31/227 (13%), Positives = 78/227 (34%), Gaps = 33/227 (14%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTLLVWVG 79
           +  ++ + +   +L+ K G    +P+  ++ I+ E G T V+   +   ++    LV   
Sbjct: 12  EKMRLKLDN---LLVQKMGQEFTVPLSDISIIVAEGGDTVVTLRLLSALSKYNIALVVCD 68

Query: 80  EAGVR--VYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA--RRSVE 135
              +   +Y S         +L  Q   +  +  +   +   +++   E   A   +S++
Sbjct: 69  NEHLPTGIYHSQNGHFRAYKRLKEQLDWSQKQKDKAWQIVTYYKINNQEDVLAMFEKSLD 128

Query: 136 QLR---------------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180
            +R                 EG   +  +  L         G+++     ++ D IN  +
Sbjct: 129 NIRLLSDYKEQIEPGDRTNREGHAAKVYFNEL--------FGKQFVRVTQKEADVINAGL 180

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKF 225
           +   + +       +   G    +G  H       + V D+ +  + 
Sbjct: 181 NYGYAIMRAQMARIVAGYGLNGLLGIFHKNEYNQFNLVDDLMEPFRQ 227


>UniRef50_B1X158 DUF48-containing protein n=12 Tax=Cyanobacteria RepID=B1X158_CYAA5
          Length = 330

 Score = 51.2 bits (121), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 44/309 (14%), Positives = 91/309 (29%), Gaps = 49/309 (15%)

Query: 18  IFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++  Q   + +      +  K  +   I +  +  +++   ++++  A+R        +
Sbjct: 4   LYVSQQGCYVKLDQETLKVEKKRQLLAEIQLPLIEQVLIFGKSQMTTQAIRACLWRNIPI 63

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLY-QAKLALDEDLRLKVVRKM--------------F 120
           V++   G   Y            L   Q +L  D   RL   R++               
Sbjct: 64  VYLSRMGY-CYGRIMSLKRGYRHLTRYQQQL--DFSQRLLTARELVKAKLKNCRVILQRQ 120

Query: 121 ELRFG---------------EPAPARRSVEQLRGIEGSRVRATYALLAKQYG---VTWNG 162
           + R                 E A    ++E+L G EG      ++            +  
Sbjct: 121 QRRLQSDKLLFAIDSLNYLIEQANLAETIERLMGFEGVGASTYFSAFGDCLTPSEFIFLA 180

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIA 220
           R   P     G+ +N  +S     L+    A I   G  P    +H G     +   D+ 
Sbjct: 181 RSRRPP----GNPVNAMLSFGYQVLWNHLLALIELQGLDPYQACLHQGSERHAALASDLI 236

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFR----SSKTLAKLIPLIEDVLAAGE 276
           +  +   V      +  R     D +        +       K L   +  +E+ +    
Sbjct: 237 EEFRAPMVDSLVLYLVNRRIMNADDDFEYHDGGCYLNNTGRKKYLKHFVQRMEETVQTTP 296

Query: 277 IQPPAPPED 285
            +   P  D
Sbjct: 297 DEKQ-PRWD 304


>UniRef50_B2KB47 CRISPR-associated protein Cas1 n=2 Tax=Elusimicrobia
           RepID=B2KB47_ELUMP
          Length = 298

 Score = 50.4 bits (119), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 31/223 (13%), Positives = 74/223 (33%), Gaps = 38/223 (17%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
            + V +  F  +     + H     +  I+L      +S+  ++   +    +++  +  
Sbjct: 13  HLCVKNNNFSAVKDREEKLHCLFDDINSIILYGNNITISNTCIQKCLEHKVPVIFCDKT- 71

Query: 83  VRVYASGQPGGARS-----DKLLYQA--------KLALD-----EDLRLKVVRKMFELRF 124
                +G    + +      +L  Q         +          + + +V+++   L+ 
Sbjct: 72  --YNPAGMLLSSFTTNIYGRRLQLQINASKPQIKQAWQQIITSKLNNQAEVLKRFDTLK- 128

Query: 125 GEPAPARRSVEQLRG----IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180
                   + E   G     EG   +  +  L   +           ++ +  D IN  +
Sbjct: 129 AAETIFNMAREVRSGDATFKEGVGAKVYFENLFNDFH----------RNTDDKDIINSAL 178

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADII 223
           +   + +      A+++AG  PAIG  H+     F   I D+I
Sbjct: 179 NYGYAIVRSSIARAVVSAGLNPAIGIFHSKNHNPFCL-IDDLI 220


>UniRef50_B1L400 CRISPR-associated protein Cas1 n=2 Tax=Archaea RepID=B1L400_KORCO
          Length = 341

 Score = 50.0 bits (118), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 50/261 (19%), Positives = 93/261 (35%), Gaps = 54/261 (20%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVW---VGEA 81
           +    G  +++ K G +  IP+ SV  +++     +S   ++  AQ GT L+     G  
Sbjct: 18  LRKRRGRILILSK-GEKKEIPMKSVKEVVIIGKAALSSELLKALAQSGTDLLIATPTGRP 76

Query: 82  GVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRK--------------MF--ELRFG 125
             R+  +   G AR+    Y++   L++   +++ R                +    R  
Sbjct: 77  VARLIPAKAGGTARNRYEQYKS---LEDRRGIEIARAVIVGKIRNQASNLSYYSKARRMD 133

Query: 126 EPAPARR---------SVEQLRGIE----GSRVRATYALLAKQYGVTW------------ 160
           E   +            +E+L+  E        +   A  +K   + W            
Sbjct: 134 EELSSELYDAAQQLKREMEELKNEEFPDIDEARKRIMARESKCANIYWEKIASIMEEWKF 193

Query: 161 NGRRYDPKDWEKG--DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFV 216
            GR     D E    D +N C++   + L       +L  G  P +G++H  +P   S V
Sbjct: 194 RGRE-KRTDLEGNVIDPVNLCLNVCYNLLSAQIWKNVLRFGLDPFLGYLHVERPGRISLV 252

Query: 217 YDIADIIKFDTVVPKAFEIAR 237
           YD+ +  +   V    F   R
Sbjct: 253 YDLMEPFRP-MVDRFVFSYLR 272


>UniRef50_B9M5J4 CRISPR-associated protein Cas1 n=9 Tax=Bacteria RepID=B9M5J4_GEOSF
          Length = 344

 Score = 50.0 bits (118), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 21/109 (19%), Positives = 44/109 (40%), Gaps = 4/109 (3%)

Query: 134 VEQLRGIEGSRVRATYALLAK--QYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
           ++Q+RG+EG    A +A+  +  + G        +       D +N  +S   + +    
Sbjct: 159 IDQVRGLEGESAAAYFAVFDQMVKDGDRAAFAMDNRNRRPPLDPMNALLSFLYTLVLNDC 218

Query: 192 EAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARR 238
            +A+ + G    +GF+H  +P   S   D+ +  +       A  +  R
Sbjct: 219 ISAVESVGLDSQMGFLHALRPGRPSLGLDLMEEFRAVIADRLALTLINR 267


>UniRef50_B4AQ39 Crispr-associated protein Cas1 n=5 Tax=Francisella
           RepID=B4AQ39_FRANO
          Length = 334

 Score = 50.0 bits (118), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 25/102 (24%), Positives = 38/102 (37%), Gaps = 11/102 (10%)

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNGRRYDPKDWEKGDTINQCISAAT 184
                 S+ +L GIEG+  +  +      YG   +W GR+   K     D  N  +    
Sbjct: 151 ELENTTSLAELMGIEGNVAKNFFKGF---YGHLDSWQGRKPRIKQ----DPYNVVLDLGY 203

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK 224
           S L+   E  +   G+    GF H    K  S V D  +  +
Sbjct: 204 SMLFNFVECFLRLFGFDLYKGFCHQTWYKRKSLVCDFVEPFR 245


>UniRef50_Q5LZX6 Putative uncharacterized protein n=2 Tax=Streptococcus thermophilus
           RepID=Q5LZX6_STRT1
          Length = 207

 Score = 49.6 bits (117), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 35/211 (16%), Positives = 73/211 (34%), Gaps = 42/211 (19%)

Query: 15  VSMIFLQYGQ--IDVIDGAFVLI-DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +S ++ Q     + + +   ++  D   I   + +  V  ++L    +++   ++  ++ 
Sbjct: 1   MSDLYSQRSNYYLSLSEQRIIIKNDNKEIVKEVSISLVDNVLLFGNAQLTTQLIKALSKN 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSD--KLLYQAKLALDEDLRLKVVRKM---------- 119
              + +    G   + S      + +  K   QAK   +ED RL+V R +          
Sbjct: 61  KVNVYYFSNVG--QFISSIETHRQDEFQKQELQAKAYFEEDFRLEVARSIATTKVRHPIA 118

Query: 120 ---------------FELRFGE---PAPARRSVEQLRGIEGSRVRA--TYALLAKQYGVT 159
                          +  RF +         S+ ++ G EG   ++   Y  L       
Sbjct: 119 LLREFDTDGLLDTSDYS-RFEDSVNDIQKAYSITEIMGYEGRLAKSYFYYLNLLVPNDFH 177

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
           +NGR   P +    D  N  ++   S LY  
Sbjct: 178 FNGRSRRPGE----DCFNSALNFGYSILYSC 204


>UniRef50_A2SQK9 Uncharacterized protein predicted to be involved in DNA repair-like
           protein n=1 Tax=Methanocorpusculum labreanum Z
           RepID=A2SQK9_METLZ
          Length = 310

 Score = 49.6 bits (117), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 44/282 (15%), Positives = 87/282 (30%), Gaps = 44/282 (15%)

Query: 33  VLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRV---YASG 89
           +++ + G  T  P+  +  +++  G  +  + +   A  G  + +    G  V   Y  G
Sbjct: 21  LIVRQKGSTTQYPLDDMRHLLIAGGHSLHTSVLERLADRGIAVSFFTAHGKPVGGIYGKG 80

Query: 90  QPGGARSDKLL-----YQAKLALDEDLRLKVVRKMFELRFGEPAPARR-----------S 133
            P  A   + +       A +    D RL+     +     E  P              +
Sbjct: 81  APSLASQQRDIPIHKFAMASIRSSLDERLR-----YINELAEFDPEGLYFKGEFDILTAA 135

Query: 134 VEQLR--------GIEGSRVRA-TYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            E+L         G   S  +   Y ++ ++       RR         D +N  +S   
Sbjct: 136 REELEYLITLPEIGRAFSLTKTMYYEIIGRKLPKVLGYRR--RCQPPFMDPVNVMMSHGY 193

Query: 185 SCLYGVTEAAILAAGYAPAIGFVH------TGKPLSFVYDIADIIKFDTVVPKAFEIARR 238
           + LY     A   AG   + G ++       G     V D+ +      V     ++A  
Sbjct: 194 AVLYANFALACTGAGLDLSRGALYGEIVSAPGGRGGCVLDLMEPATVSMVDRVIIQMAAE 253

Query: 239 N--PGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
               G  +   R    +  +  + + +L   I   L    + 
Sbjct: 254 GRLDGAYEVTTRCLLSNELKE-EFMKRLHGSINITLIEENVN 294


>UniRef50_C7XMU1 CRISPR-associated protein cas1 n=2 Tax=Fusobacterium
           RepID=C7XMU1_9FUSO
          Length = 292

 Score = 49.2 bits (116), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 36/266 (13%), Positives = 88/266 (33%), Gaps = 28/266 (10%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGT-RVSHAAVRLAAQVGTLLVWVGE 80
             ++D+   +  +    G    I +G V  ++LE  T  ++ A +    +    +++  E
Sbjct: 12  RSKLDLRYNSISIRRDNGTDF-IHIGEVNTLILETTTISITAALMCELIKQKVKVIFCDE 70

Query: 81  AGVRVY-ASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRG 139
                +      G       + +     D          ++ +   E    +  + +   
Sbjct: 71  KSNPHFELLPFYGSHDCSAKIKEQIAWTDFLK-----ESLWTIIVTEKIENQMKLLKKLN 125

Query: 140 IEGSRVRATYALL----------AKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
            E  ++   YA                 + ++    +     K +++N  ++     L  
Sbjct: 126 KEEYKILQEYASQIEHNDNTNREGHSAKIYFSALFGNNFSRNKENSLNAFLNYGYQLLLS 185

Query: 190 VTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREV 247
                I+A GY   IG  H       +   D+ +  +   V   A+   + NP + +++ 
Sbjct: 186 TFNKEIVANGYLTQIGIFHKNMFNYYNLSSDLMEPFRV-IVDELAY---KENPQKFEKDE 241

Query: 248 RLACRDI----FRSSKTLAKLIPLIE 269
           +   ++I    FR +     L  +I+
Sbjct: 242 KRKLQNILNLKFRINNVNHYLSDIIK 267


>UniRef50_D1VVR4 CRISPR-associated endonuclease Cas1, DVULG subtype n=1
           Tax=Peptoniphilus lacrimalis 315-B RepID=D1VVR4_9FIRM
          Length = 343

 Score = 49.2 bits (116), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 5/98 (5%)

Query: 135 EQLRGIEGSRVRATYALLAKQYGVTWNGRRY--DPKDWEKGDTINQCISAATSCLYGVTE 192
           + +RGIEG+  R  +++L  ++ V      Y  +       D  N  +S   S L     
Sbjct: 159 DSIRGIEGTIARQYFSVL-DEFIVKQREDFYFIERTKRPPRDRFNAMLSFMYSILTNSIA 217

Query: 193 AAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTV 228
           +A+   G     GF HT +P   S   DI + ++   +
Sbjct: 218 SALEGVGIDSYAGFFHTDRPGRVSMALDIIEEMRAFII 255


>UniRef50_A8TI31 CRISPR-associated protein Cas1 n=1 Tax=Methanococcus voltae A3
           RepID=A8TI31_METVO
          Length = 235

 Score = 48.8 bits (115), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 29/123 (23%), Positives = 45/123 (36%), Gaps = 15/123 (12%)

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SF 215
             +  R   P + E    IN  IS   S LY    + I      P++ ++H       S 
Sbjct: 81  FKYEKRSRRPPENE----INALISFGNSLLYSTVISEIFNTHLNPSVSYLHEPYERRYSL 136

Query: 216 VYDIADIIKFDTVVPKAFEIARR---NPGEPDREVRLAC-----RDIFRSSKTLAKLIPL 267
             DIAD+ K   V    F +  +   N    ++++         R IF S K   +L   
Sbjct: 137 ALDIADVFKPIFVDRLIFNLVNKKIINENHFEKDLNSCLLNDEGRAIFLS-KYNERLQKT 195

Query: 268 IED 270
           I+ 
Sbjct: 196 IKH 198


>UniRef50_P71636 CRISPR-associated protein Cas1 n=11 Tax=Mycobacterium tuberculosis
           complex RepID=P71636_MYCTU
          Length = 338

 Score = 47.7 bits (112), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 23/114 (20%), Positives = 39/114 (34%), Gaps = 8/114 (7%)

Query: 133 SVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
           S+ +L G EG+  +A +  L         + GR   P      D  N  +S   S LY  
Sbjct: 147 SLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPP----LDAFNSMVSLGYSLLYKN 202

Query: 191 TEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGE 242
              AI        IGF+H       +   D+ ++ +   +      +      +
Sbjct: 203 IIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVD 256


>UniRef50_B2UP48 CRISPR-associated protein Cas1 n=1 Tax=Akkermansia muciniphila ATCC
           BAA-835 RepID=B2UP48_AKKM8
          Length = 311

 Score = 47.7 bits (112), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 31/222 (13%), Positives = 61/222 (27%), Gaps = 26/222 (11%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLVWV--- 78
             +    G     D       IP+  V  ++L      ++   +   A+     V     
Sbjct: 13  CHLSCDKGQLRCADGENSPRTIPLEDVGAVVLSSFKATLTSNLLIELARKRIGFVLCESY 72

Query: 79  ------------GEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
                        + G+  + +  P   R+                L            E
Sbjct: 73  RPAVLLLPADRSTDTGLLRHLADMPARLRNRLWQKTLDAKCGNQTALAQAWNPHHPAIAE 132

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
                 + +  R  E +R+   +++ A     TW    +     E+G   N   + A + 
Sbjct: 133 LKRMAVTEKTAREAECARL--FWSVFAD----TWANSDFRRGRHEEG--FNNLFNYAYAI 184

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFD 226
           L       + A G  P  G  H  +  +    YD+ +  +  
Sbjct: 185 LLSCILQYLFALGLDPCFGIFHQSREHAAPLAYDLMEPFRPA 226


>UniRef50_UPI00016B206F hypothetical protein cdiviTM7_00753 n=1 Tax=candidate division TM7
           single-cell isolate TM7c RepID=UPI00016B206F
          Length = 296

 Score = 47.7 bits (112), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 37/261 (14%), Positives = 90/261 (34%), Gaps = 35/261 (13%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVGTLLVWVGEA 81
            ++ + D   V+  +T     +P+  +  ++L   G   +   +   A  GT  +   E 
Sbjct: 12  ARLSLRDNQLVIAQETEAT--LPIEDIDSLILDGYGITTTTNLLAALATKGTTTIICDEK 69

Query: 82  GVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQ--LR- 138
            +   AS     ++      QAK+      ++ + + + +  + +   ++ + +   LR 
Sbjct: 70  HLP--ASVLLPYSQHS---RQAKV---SRQQIAMSQPLKKQLWQQIIISKITNQADVLRS 121

Query: 139 -GIEGSRVRATYALLAKQYGVTWNGRRYDPK---------DWEKGDTI--NQCISAATSC 186
            G++ + +R     ++       + R              D  +   I  N  ++   + 
Sbjct: 122 TGLDDAALRT---HISDVKSGDTSNRESIAARIYFDQLLDDATRRKPIWHNTALNYGYAM 178

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPD 244
           +       I A G   + G  H  +  SF    D+ +  +    +    ++A  + G+ D
Sbjct: 179 VRSHIARHIAARGLVASQGIFHHNELNSFNLADDLIEPYRAAVDLYVLEKVAPLHVGDRD 238

Query: 245 ----REVRLACRDIFRSSKTL 261
               +  R    DI      +
Sbjct: 239 ASLTKHDRQLIIDILNYYVIM 259


>UniRef50_A8LN06 CRISPR-associated protein Cas1 n=2 Tax=Rhodobacterales
           RepID=A8LN06_DINSH
          Length = 303

 Score = 47.7 bits (112), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 41/255 (16%), Positives = 75/255 (29%), Gaps = 18/255 (7%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSV-ACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
            +    G   + +       IP+  +   I+   GT  + + +   A  G  +V  G   
Sbjct: 13  HLSRDRGFLKVSEGAREIGRIPLDQIAGVIVHAHGTTWTTSLLTELADRGAPVVLCGANH 72

Query: 83  VR------VYASGQPGGARSDKLLYQAKLALDEDLRLKVVR-KMFELRFGEPAPARRSVE 135
                   +      G     +   +A L      +  + +  M              V 
Sbjct: 73  APRSVLMPLDGHHAQGARLRAQWQARAPLVKQAWKQTVIAKIAMQAAALEAMGEPHAPVG 132

Query: 136 QL-RGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAA 194
            L R +         A  A+ Y     G  +   D    D +N  ++   + L   T  A
Sbjct: 133 MLARKVTSGDATNVEAQAARLYWPRMMGTEFRR-DRTAPD-LNALLNYGYTVLRAATARA 190

Query: 195 ILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACR 252
           ++AAG  P IG  H+ +  +F    D+ +  +     P      R        +V  A +
Sbjct: 191 VVAAGLHPTIGLHHSNRGNAFALADDLMEPFR-----PLVDCCVRGLAARNGPQVDPAAK 245

Query: 253 DIFRSSKTLAKLIPL 267
                   L   +  
Sbjct: 246 QSLARLIALDLPLGD 260


>UniRef50_C8N6V7 Putative uncharacterized protein n=1 Tax=Cardiobacterium hominis
           ATCC 15826 RepID=C8N6V7_9GAMM
          Length = 334

 Score = 46.9 bits (110), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 40/255 (15%), Positives = 88/255 (34%), Gaps = 48/255 (18%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +++     ++ V     +  +     + +P+  +  I ++    +S A +    +  
Sbjct: 1   MSTLYIDRQNTRMTVSGNTLIFYENGERASTLPLHIIDRICIKGDLALSAADLGKLGEHN 60

Query: 73  TLLVWVGE--------------AGVRVYASGQPGGARSDKLLYQAKLALDEDLRLK--VV 116
             ++ +                  +R  A        +     QA+  + E ++ +  ++
Sbjct: 61  IGVLILSGREQQPTIYLPCARKDALRRLAQAH-FSQDNTFCTRQAQSWITEKIQREQDLL 119

Query: 117 RKMFEL--RFGEPAPARR---------------SVEQLRGIEGSRVRATYALLAKQY--G 157
           R++     R G                       +  LRGIEGS   +T+A +A      
Sbjct: 120 RELQTRPHRGGHQLHENLEQLEKSRLRLQNPINDLATLRGIEGSAASSTFAAIACVLPES 179

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCL-YGVTEAAILAAGYAPAIGFVHT---GKPL 213
           + +  R  +P      D  N  +S   + L Y +    I   G  P IG+ H+   G+  
Sbjct: 180 LHFTKRNRNPPR----DPYNVGLSLGYTLLHYAMVRQ-IHLTGLDPCIGYYHSIEHGRE- 233

Query: 214 SFVYDIADIIKFDTV 228
           S   D+ + ++    
Sbjct: 234 SLACDLIEAMRPLVT 248


>UniRef50_A6DE79 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Caminibacter
           mediatlanticus TB-2 RepID=A6DE79_9PROT
          Length = 281

 Score = 46.9 bits (110), Expect = 0.001,   Method: Composition-based stats.
 Identities = 26/152 (17%), Positives = 55/152 (36%), Gaps = 10/152 (6%)

Query: 133 SVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTE 192
           S + L GIEG+  +  +      +  T    +         D +N  +S   + LY    
Sbjct: 126 SKDSLLGIEGNFAKEYFKEYFSLFDKTLT--KGYRSKRPPEDVVNALMSYLYTLLYYEIA 183

Query: 193 AAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPK--AFEIARRNPGEPDREVR 248
             ++  G+   I ++H      +S   D+ ++ + D  V     F+  +       ++  
Sbjct: 184 NRLIFYGFEVGISYLHESFRDHMSLASDLLEVFRSDVDVFVYEMFDNKKV----IKKDFT 239

Query: 249 LACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
              + IF  S+   ++   I+D     +I   
Sbjct: 240 KEKKGIFLRSEKRKEIWSDIKDFFENLKIDEE 271


>UniRef50_A6VLA8 CRISPR-associated protein Cas1 n=13 Tax=Proteobacteria
           RepID=A6VLA8_ACTSZ
          Length = 305

 Score = 46.5 bits (109), Expect = 0.001,   Method: Composition-based stats.
 Identities = 40/239 (16%), Positives = 86/239 (35%), Gaps = 29/239 (12%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTR 59
           MTW     I +           G++ +      LI + G    +P+  +A +++E   T 
Sbjct: 1   MTW---RSILMSKG--------GKLSLQQNQM-LIQQEGNEFTVPLEDIAIVVVESRETV 48

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGA-----RSDKLLYQAKLALDEDLRLK 114
           ++   +      G   +   E  +       P        ++ KL  +A L   + L   
Sbjct: 49  ITIPLLSAFGLHGVTFLTCDEQFLPC-GQWLPFNQYHRQLKTLKLQLEASLPQKKQLWQA 107

Query: 115 VVRKMFELRFGEPAPARRSVEQLRGIEGS-RVRA-----TYALLAKQYGVTWNGRRYDPK 168
           +V++    + G     +   E  R ++ + +V++       A  A  Y  T  G+ +   
Sbjct: 108 IVQQKIRNQAGVLKICKFQAESDRLLKMAEKVKSGDKENLEAQSAVIYFQTLFGKGFKRS 167

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKF 225
           + E    +N  ++   + +      A++  G+ P IG  H  +  +F    D  +  + 
Sbjct: 168 EDES--AVNSALNYGYTVMRSAVARALVLYGWLPQIGLFHRSELNAFNLADDFIEPFRP 224


>UniRef50_A9AX66 CRISPR-associated protein Cas1 n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9AX66_HERA2
          Length = 350

 Score = 46.5 bits (109), Expect = 0.001,   Method: Composition-based stats.
 Identities = 41/284 (14%), Positives = 80/284 (28%), Gaps = 56/284 (19%)

Query: 18  IFL--QYGQIDVIDGAFVLI---DKTGIR----THIPVGSVACIMLEPGTRVSHAAVRLA 68
           ++L  QY  +     A  +    D+   R      +P+  +  ++++    ++ +A+   
Sbjct: 4   LYLSEQYSIVKREGEALRVEIPEDQQLGRQRQVVRVPLNVIERVVVQGEITLTASALACL 63

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------- 119
            +      ++  +G    A        +   L Q         R  + R           
Sbjct: 64  LERRICTHFLSYSGRSQGALTPDPTRNASLRLAQYAAHTSIQHRFSLARTFVDGKLRNLR 123

Query: 120 -FELRFGE-PAPARRS--VEQLR----------------------------GIEGSRVRA 147
              LRF         +  +E+LR                            G EG    A
Sbjct: 124 TQILRFNRSQREPTLTQAIERLRDAHRDLHGLSIPEYVDPLDRMHGMGQILGCEGQGSAA 183

Query: 148 TYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFV 207
            +          W    +  +     D +N  +S     L     + +   G+ P IGF+
Sbjct: 184 YWDCWGMLLNQPW--EWHGRRRRPPPDPVNALLSYGYVILTSQVLSQLAIVGFDPYIGFL 241

Query: 208 HT---GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVR 248
           H    GKP +   D+ +  +   V      +            R
Sbjct: 242 HQSSFGKP-ALALDLMEEFRPVIVDSVVLTVLNTKILNQQHFQR 284


>UniRef50_C9RJP2 CRISPR-associated protein Cas1 n=21 Tax=cellular organisms
           RepID=C9RJP2_FIBSS
          Length = 298

 Score = 46.2 bits (108), Expect = 0.001,   Method: Composition-based stats.
 Identities = 16/100 (16%), Positives = 34/100 (34%), Gaps = 11/100 (11%)

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKA 232
             N  ++   + L GV   A++++G  P +G  H  +  ++    DI +  +   V    
Sbjct: 174 PPNNMLNYGYAILRGVVARALVSSGLLPTLGIHHHNRYNAYCLADDIMEPYRP-IVDKLI 232

Query: 233 FEIARRNPGEP--------DREVRLACRDIFRSSKTLAKL 264
            E+       P         + +R+   D          +
Sbjct: 233 LEVINEIEEYPTDLSTEIKAKLLRIPVLDCVIDGNRSPLM 272


>UniRef50_C0WE67 Crispr-associated protein n=1 Tax=Acidaminococcus sp. D21
           RepID=C0WE67_9FIRM
          Length = 290

 Score = 45.4 bits (106), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/214 (12%), Positives = 68/214 (31%), Gaps = 11/214 (5%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLE-PGTRVSHAAVRLAAQVGTLLVWVG 79
           Q  ++D       +      +  I +  +  +++E  G  ++   +         L++  
Sbjct: 10  QRCKLDFCMNYVEVQTAV-SKKRIFIDEIKTLIIENTGVAITAYLLSELMNRKVNLIFCD 68

Query: 80  EAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLR-----LKVVRKMFELRFGEPAPARRS 133
           +A     +         S + + Q  +   E        +   +   +  F +    +  
Sbjct: 69  KAHNPQSSLLPLHARFDSIRKIKQQMIWSQEIKDEVWDCIVKAKIRQQALFLDELEKKEQ 128

Query: 134 VEQLRG-IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTE 192
            + L   ++       +        V +N    +    +    IN  ++   S L  +  
Sbjct: 129 SKMLMSYLDDVVSADAHNREGHAAKVYFNALFGNSFTRDLDSPINAGLNYGYSLLLSLFN 188

Query: 193 AAILAAGYAPAIGFVHTG--KPLSFVYDIADIIK 224
             I++AGY   +G  H     P +F  D+ +  +
Sbjct: 189 REIVSAGYLTQLGIFHENTYNPYNFSCDLMEPFR 222


>UniRef50_B0VHC1 Putative uncharacterized protein n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VHC1_9BACT
          Length = 344

 Score = 45.4 bits (106), Expect = 0.002,   Method: Composition-based stats.
 Identities = 22/95 (23%), Positives = 34/95 (35%), Gaps = 11/95 (11%)

Query: 137 LRGIEGSRVRATYALLAKQYG---VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEA 193
           L G EG   +  +A            ++GR   P      D +N  +S + + L      
Sbjct: 155 LLGYEGIAAKNYFAAFPDLIANPDFPFSGRNKRPPK----DEVNAMLSLSYTFLMNQVMC 210

Query: 194 AILAAGYAPAIGFVHT---GKPLSFVYDIADIIKF 225
           A    G  P  G +H    G+  S V DI +  + 
Sbjct: 211 AAYICGLDPYYGALHDLDYGRQ-SLVLDIMEEFRP 244


>UniRef50_C7G696 CRISPR-associated protein Cas1 n=2 Tax=Roseburia RepID=C7G696_9FIRM
          Length = 301

 Score = 45.4 bits (106), Expect = 0.003,   Method: Composition-based stats.
 Identities = 43/225 (19%), Positives = 83/225 (36%), Gaps = 21/225 (9%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGT-RVSHAAVRLAAQVGTLLVWVGE 80
           + ++ + +    +  +T I   IP+  + CI++E  T  VS   ++  A +G  +    E
Sbjct: 11  HVKLSIKNQQLNI--ETDIARQIPLEDINCIIIENQTVTVSAYLLQKMADMGIAVYVCDE 68

Query: 81  AGVRVYASGQPGGARSD---KLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSV--- 134
             +   A   P    S     L YQ +       RL     + ++R      A   +   
Sbjct: 69  KHLPN-AVLLPMVRHSRHFKILKYQIEAGKPLQKRLWQQIVVQKIRNQALCLAYLELDGS 127

Query: 135 EQLRGI-----EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
           E+L  +      G R     A  A  Y  +  G  +   +      IN  ++   + + G
Sbjct: 128 EELMKMCKEVQSGDRT-HVEAKAAAFYFKSLYGLGFSRGNDH---IINAALNYGYAIVRG 183

Query: 190 VTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKA 232
           +   +I+  G  P+IG  H  +  +F    D+ +  +    +  A
Sbjct: 184 LIARSIVCYGLEPSIGVFHHSELNNFNLADDMIEPFRPLVDLYVA 228


>UniRef50_Q03JI7 CRISPR-associated protein, Cas1 family n=40 Tax=Bacilli
           RepID=Q03JI7_STRTD
          Length = 289

 Score = 45.4 bits (106), Expect = 0.003,   Method: Composition-based stats.
 Identities = 36/293 (12%), Positives = 82/293 (27%), Gaps = 48/293 (16%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV--SHAAVRLAAQVGTLLVWVG 79
           + ++   +   +  +       I +  +  ++LE  T +  +   V+       L+++  
Sbjct: 12  HSKLSYKNNHLIFRNSYKTEM-IHLSEIDILLLET-TDIVLTTMLVKRLVDENILVIFCD 69

Query: 80  EAG------VRVYA--------SGQPGGARSDKLLYQAKLAL----DEDLRLKVVRKMFE 121
           +           YA        + Q     + K      +      ++   L       +
Sbjct: 70  DKRLPTAFLTPYYARHDSSLQIARQIAWKENVKCEVWTAIIAQKILNQSYYLGECSFFEK 129

Query: 122 LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCIS 181
            +                 EG   R  +  L   +G  +          E  + IN  + 
Sbjct: 130 SQSIMELYHGLERFDPSNREGHSARIYFNTL---FGNDFTR--------ESDNDINAALD 178

Query: 182 AATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRN 239
              + L  +    ++  G    IG  H       +   DI +  +     P    I  +N
Sbjct: 179 YGYTLLLSMFAREVVVCGCMTQIGLKHANQFNQFNLASDIMEPFR-----PIIDRIVYQN 233

Query: 240 PGEPDREVRLACRDIFRSSKT-------LAKLIPLI-EDVLAAGEIQPPAPPE 284
                 +++     IF  +         L+ ++    + V+ A        PE
Sbjct: 234 RHNNFVKIKKELFSIFSETYLYNGKEMYLSNIVSDYTKKVIKALNQLGEEIPE 286


>UniRef50_D0WRI5 CRISPR-associated protein Cas1, NMENI subtype n=3
           Tax=Actinomycetales RepID=D0WRI5_9ACTO
          Length = 238

 Score = 45.0 bits (105), Expect = 0.004,   Method: Composition-based stats.
 Identities = 27/119 (22%), Positives = 40/119 (33%), Gaps = 11/119 (9%)

Query: 152 LAKQYGVTWNG------RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIG 205
            A+   + W         R  P         N  +  A + L G    A+L AG +P IG
Sbjct: 84  EARAARLYWQALWGEESFRRHPGLGSGESCRNSHLDYAYTVLRGHGIRAVLGAGLSPTIG 143

Query: 206 FVHTGKPLSF--VYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLA 262
             H G+  +F  V DI +  +    +  +      N    D EVR          + L 
Sbjct: 144 LFHHGRSNNFALVDDIIEPFRP--AIDSSVSRLAPNADMKDPEVRKHLVAA-ADQRFLP 199


>UniRef50_B3DR65 Putative uncharacterized protein n=1 Tax=Bifidobacterium longum
           DJO10A RepID=B3DR65_BIFLD
          Length = 139

 Score = 44.6 bits (104), Expect = 0.005,   Method: Composition-based stats.
 Identities = 16/84 (19%), Positives = 31/84 (36%), Gaps = 4/84 (4%)

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFE 234
           N  +  A   L G    A++AAG  P++G  H G+   F    D+ ++ +       +  
Sbjct: 19  NAQLDYAYMVLRGFAVKAVIAAGLIPSLGVNHHGRGNYFCLADDLLEVYRPAVDYRVS-- 76

Query: 235 IARRNPGEPDREVRLACRDIFRSS 258
           +        ++ V+    D     
Sbjct: 77  LLNDEDSLQEKAVKKHLVDAVNQQ 100


>UniRef50_B9CMG3 CRISPR-associated protein Cas1, NMENI subtype n=1 Tax=Atopobium
           rimae ATCC 49626 RepID=B9CMG3_9ACTN
          Length = 215

 Score = 44.2 bits (103), Expect = 0.005,   Method: Composition-based stats.
 Identities = 29/164 (17%), Positives = 56/164 (34%), Gaps = 24/164 (14%)

Query: 97  DKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY 156
           DK+ +QA+  L+   R ++ +++F L   E      +       E    R  +  L   +
Sbjct: 34  DKITHQAQ-VLNARAREEIGQQLFGL-IPEVRSGDTT-----NREAHAARLYFHAL---F 83

Query: 157 GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFV 216
           G  ++         +    IN  +    + L       I+A GY    G  H  +   F 
Sbjct: 84  GHEFSR--------DDETPINAALDYGYAILLSAVNREIVARGYLTQSGICHRSEYNQFN 135

Query: 217 Y--DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSS 258
              D  +  +   V    F+      G+  ++ +    D+   S
Sbjct: 136 LGCDFMEPFRP-IVDRLVFDNV---EGDFTKDTKRLLIDMLNQS 175


>UniRef50_UPI000174611D CRISPR-associated protein Cas1/Cas4 n=1 Tax=Verrucomicrobium
           spinosum DSM 4136 RepID=UPI000174611D
          Length = 847

 Score = 44.2 bits (103), Expect = 0.006,   Method: Composition-based stats.
 Identities = 48/302 (15%), Positives = 85/302 (28%), Gaps = 63/302 (20%)

Query: 5   PLNPIPLKDRVSMIFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           P   +  +D    ++L      +       V+ D   +     +  +  + +    +++ 
Sbjct: 485 PRRLMAARDDARALYLSTPGYHVGRSGELLVVKDGASLVEEFRINDLTNVAVFGNVQITT 544

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE- 121
            AV++  +    L +    G     +           + Q + A D    L + R+    
Sbjct: 545 QAVQVLCEKEIPLAYFSTGGWFYGLTRGHVTKNVFTRIEQFRAADDPMRCLALSRRFVAG 604

Query: 122 ---------LRFGEPAPAR---------------RSVEQLRGIEGSRVRATYALLA---- 153
                    +R     PA                RS+E L GIEG+         A    
Sbjct: 605 KIRNHRTLLMRLHVEPPAAVLARLKQASQDALGARSLETLLGIEGAAAALYLQHFAGMIK 664

Query: 154 ------------------------KQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
                                     +   +  R   P      D +N  +S A S L  
Sbjct: 665 VGAADDDDEIPGLESASATRVPEESVFTFDFTKRSRRPP----TDPVNALLSLAYSLLAK 720

Query: 190 VTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDRE 246
               A  A G+ P +GF H    G+P +   D+ +  +                  PD  
Sbjct: 721 DCTIAAHAVGFDPYVGFYHQPRYGRP-ALALDLMEEFRPLVAESVVLTAINNRMLVPDHF 779

Query: 247 VR 248
           VR
Sbjct: 780 VR 781


>UniRef50_C2EF73 CRISPR-associated Cas1 family protein n=1 Tax=Lactobacillus
           salivarius ATCC 11741 RepID=C2EF73_9LACO
          Length = 308

 Score = 43.8 bits (102), Expect = 0.007,   Method: Composition-based stats.
 Identities = 20/127 (15%), Positives = 40/127 (31%), Gaps = 12/127 (9%)

Query: 141 EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGY 200
           E    R  ++ L   +  ++   RYD       D IN  ++   + L       ++  G 
Sbjct: 156 EAYAARVYFSNL---FSKSFKRGRYD-------DIINSSLNYGYAILRSAIRKELVIYGL 205

Query: 201 APAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSS 258
            P+ G  H      F    DI ++ +          +      E D E++     +    
Sbjct: 206 EPSWGIHHVSTENPFNLSDDIIEVYRPFLDALVVELLNNNESEELDIELKKEIIKVLFEK 265

Query: 259 KTLAKLI 265
             +   +
Sbjct: 266 CIIDNKV 272


>UniRef50_D1AUW5 CRISPR-associated protein Cas1 n=1 Tax=Streptobacillus moniliformis
           DSM 12112 RepID=D1AUW5_STRM9
          Length = 308

 Score = 43.8 bits (102), Expect = 0.008,   Method: Composition-based stats.
 Identities = 29/162 (17%), Positives = 52/162 (32%), Gaps = 31/162 (19%)

Query: 135 EQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAA 194
             ++  EG+  +  +  L   YG  +  +        + D+IN  +       YGV  +A
Sbjct: 143 SDVQNREGTAAKVFFNYL---YGTNFCRQ-------NERDSINMALDYG----YGVFRSA 188

Query: 195 ILAA----GYAPAIGFVHTGKPLSF--VYDIADIIKFDTVVPKAFEIARRNPGEPD--RE 246
           I       G+A  IG  H+    +F   YD  +  +   +    F    R   + +   +
Sbjct: 189 ITRLLCTYGFATYIGVHHSSMMNAFNLTYDFIEPYRP-IIDYYVFNHLYRFEKDDELKTD 247

Query: 247 VRLACRDIFR--------SSKTLAKLIPLIEDVLAAGEIQPP 280
            R     +              L  +  LI+  L   E    
Sbjct: 248 TRKELISLLNANIKVNEKEYTVLYSMELLIKSYLNFLEEGNE 289


>UniRef50_C8PNV3 CRISPR-associated protein Cas1 n=1 Tax=Treponema vincentii ATCC
           35580 RepID=C8PNV3_9SPIO
          Length = 296

 Score = 43.1 bits (100), Expect = 0.013,   Method: Composition-based stats.
 Identities = 31/225 (13%), Positives = 82/225 (36%), Gaps = 23/225 (10%)

Query: 18  IFLQYGQ-IDVIDGAFVLIDKTG-IRTHIPVGSVACIMLE-PGTRVSHAAVRLAAQVGTL 74
           +F  +   + V     V+  +     T +P+  +  +++E     ++   +    +    
Sbjct: 6   LFFSHAVCLSVKHKQLVIFSEETQEETLVPIEDIGFVIVENERVSLTIPLINELTENNCA 65

Query: 75  LVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM------FELRFGEPA 128
           L++  E  +             +++  Q   +   + +L V +K       ++++     
Sbjct: 66  LIFCNEKHMPF---SMTMPLDCNEIQSQL-FSAQINAKLPVKKKCWKQVVEYKIKNQGLL 121

Query: 129 PARRSVEQLRGIE-GSRVRA-----TYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISA 182
             +  ++  R  +   RV++       +  AK Y     G+ +    +  G+  N  ++ 
Sbjct: 122 LKKYDLDFARLADFSKRVKSGDSTNMESQAAKFYWDNLFGKNWCRNRF--GEFPNNYLNY 179

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKF 225
             + L   T  A+  +G  PA+G  H  K  ++    D+ +  + 
Sbjct: 180 GYAILRAATARALAGSGLLPALGIHHHNKYNAYCLADDLMEPYRP 224


>UniRef50_B8I084 CRISPR-associated protein Cas1 n=1 Tax=Clostridium cellulolyticum
           H10 RepID=B8I084_CLOCE
          Length = 298

 Score = 42.3 bits (98), Expect = 0.024,   Method: Composition-based stats.
 Identities = 33/222 (14%), Positives = 65/222 (29%), Gaps = 34/222 (15%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTLLVWVGEAG 82
           ++ +      +    G    IP+  +  I+L+     ++ A +   A+    L       
Sbjct: 13  KLKLKQNNLWVEQSDG--FSIPIDDINTIVLDSADVTITSALLSKLAEEDIALYSCDGKH 70

Query: 83  VRV--YASGQPGGARSDKLLYQAKLALDEDLR---LKVVRKMFELRF--------GEPAP 129
                         +   +  Q  L+     R     V +K+    F        G    
Sbjct: 71  TPNGVLLPFSCHSRQYKIVKTQINLSAPFKKRCWQRVVQQKIENQAFCLNILELKGRDEL 130

Query: 130 ARRSVEQLRG----IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
              S   L G    +E    +  +++L            +        D  N  ++   S
Sbjct: 131 INLSKSVLSGDSTNVEAHAAKYYFSVL------------FTNFKRGMQDNTNYALNYGYS 178

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKF 225
            L G     I + G+ P+IG  H  +  +F    D  +  + 
Sbjct: 179 ILRGAVARTIASYGFIPSIGIHHRSELNNFNLADDFIEPFRP 220


>UniRef50_A9GQD8 Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So
           ce 56' RepID=A9GQD8_SORC5
          Length = 310

 Score = 40.4 bits (93), Expect = 0.080,   Method: Composition-based stats.
 Identities = 36/194 (18%), Positives = 55/194 (28%), Gaps = 41/194 (21%)

Query: 91  PGGARSDKLLYQAKLALDED-----------LRLKVVRKMFELRFGEPAPARRS------ 133
                 +  + Q + A DE             ++K  R M       P  A  S      
Sbjct: 56  LESRNVELRVAQHRAASDEAFCLSFARGVVVSKIKNARTMLRRNHAAPEVAVLSELDQLA 115

Query: 134 --------VEQLRGIEGSRVRATYALLA--------KQYGVTWNGRRYDPKDWEKGDTIN 177
                   +  L GIEG+  R  +   A         +      GR   P      D +N
Sbjct: 116 RKAAEAPSLPSLLGIEGTAARVYFGAFAGMLKGAGEARGEFDLEGRNRRPPR----DPVN 171

Query: 178 QCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIADIIKFDTVVPKAFE 234
             +S A + L       +   G  P +GF H    G+P +   D+ +  +          
Sbjct: 172 ALLSLAYALLAKDLATTLGTVGLDPLLGFYHQPRFGRP-ALALDLIEEFRPIVADSVVVA 230

Query: 235 IARRNPGEPDREVR 248
                   PD   R
Sbjct: 231 AINNGVVAPDDFQR 244


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_Q46896 Uncharacterized protein ygbT n=119 Tax=cellular ...   326   9e-88
UniRef50_D1NTI3 CRISPR-associated protein Cas1 n=10 Tax=Bacteria...   305   1e-81
UniRef50_D1A5U2 CRISPR-associated protein Cas1 n=3 Tax=Actinomyc...   295   1e-78
UniRef50_D1CAI8 CRISPR-associated protein Cas1 n=3 Tax=Bacteria ...   292   1e-77
UniRef50_Q2JWC7 CRISPR-associated protein Cas1 n=3 Tax=Chroococc...   290   4e-77
UniRef50_C7QEM2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria ...   289   9e-77
UniRef50_D1CGD6 CRISPR-associated protein Cas1 n=7 Tax=cellular ...   285   1e-75
UniRef50_B4V4P5 Crispr-associated protein cas1 n=4 Tax=Streptomy...   285   1e-75
UniRef50_C1YVP5 CRISPR-associated protein Cas1 n=1 Tax=Nocardiop...   284   3e-75
UniRef50_D2RB04 CRISPR-associated endonuclease Cas1, ECOLI subty...   283   5e-75
UniRef50_C7LYW4 CRISPR-associated protein Cas1 n=1 Tax=Acidimicr...   281   3e-74
UniRef50_B1VIX8 CRISPR-associated protein n=6 Tax=Corynebacteriu...   279   6e-74
UniRef50_C7MTM5 CRISPR-associated protein, Cas1 family n=6 Tax=A...   278   2e-73
UniRef50_Q3ZZ81 CRISPR-associated protein Cas1 n=4 Tax=Bacteria ...   277   3e-73
UniRef50_A8M406 CRISPR-associated protein Cas1 n=5 Tax=Actinomyc...   274   3e-72
UniRef50_C7MTL6 CRISPR-associated protein, Cas1 family n=4 Tax=A...   264   2e-69
UniRef50_C2BS02 CRISPR-associated protein n=1 Tax=Mobiluncus cur...   264   3e-69
UniRef50_Q03C58 CRISPR-associated protein n=3 Tax=Lactobacillus ...   261   2e-68
UniRef50_Q47PJ6 CRISPR-associated protein, Cas1 family n=4 Tax=A...   244   4e-63
UniRef50_C4X9I5 CRISPR-associated Cas1 family protein n=12 Tax=B...   242   9e-63
UniRef50_B6IWM1 CRISPR-associated protein Cas1, putative n=1 Tax...   238   2e-61
UniRef50_C9M9R9 CRISPR-associated protein Cas1 n=1 Tax=Jonquetel...   233   5e-60
UniRef50_Q21QB1 CRISPR-associated protein Cas1 n=1 Tax=Rhodofera...   225   2e-57
UniRef50_C8W2P4 CRISPR-associated protein Cas1 n=1 Tax=Desulfoto...   224   2e-57
UniRef50_Q0AA34 CRISPR-associated protein Cas1 n=11 Tax=Bacteria...   222   9e-57
UniRef50_C1ZJF3 CRISPR-associated protein, Cas1 family; CRISPR-a...   221   2e-56
UniRef50_D0MKV7 CRISPR-associated protein Cas1 n=1 Tax=Rhodother...   220   4e-56
UniRef50_UPI00016C522C CRISPR-associated protein Cas1/Cas4 n=1 T...   220   4e-56
UniRef50_Q467D6 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Meth...   218   3e-55
UniRef50_Q74H36 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Geob...   217   3e-55
UniRef50_C2KP50 CRISPR-associated Cas1 family protein n=5 Tax=Ac...   216   9e-55
UniRef50_C7QUZ4 CRISPR-associated protein Cas1 n=8 Tax=Cyanobact...   215   1e-54
UniRef50_C3WS02 CRISPR-associated protein n=2 Tax=Fusobacterium ...   215   1e-54
UniRef50_B9K7F7 CRISPR-associated protein, Cas1 family n=1 Tax=T...   214   4e-54
UniRef50_B7KMR5 CRISPR-associated protein Cas1 n=3 Tax=Chroococc...   214   5e-54
UniRef50_B8GLF6 CRISPR-associated Cas1/Cas4 family protein n=1 T...   210   4e-53
UniRef50_A5ILM3 CRISPR-associated protein, Cas1 family n=3 Tax=B...   210   5e-53
UniRef50_UPI0001C16754 protein of unknown function DUF48 n=1 Tax...   208   2e-52
UniRef50_C9M4E6 CRISPR-associated protein cas1 n=1 Tax=Lactobaci...   207   3e-52
UniRef50_C4G3M4 Putative uncharacterized protein n=1 Tax=Abiotro...   207   3e-52
UniRef50_C1DUM1 Crispr-associated protein Cas1 n=18 Tax=Bacteria...   207   5e-52
UniRef50_B9YDC3 Putative uncharacterized protein n=1 Tax=Holdema...   207   6e-52
UniRef50_B7IHY4 Cas crispr-associated protein Cas1 n=4 Tax=Bacte...   206   7e-52
UniRef50_D2NTT1 Uncharacterized protein predicted to be involved...   206   7e-52
UniRef50_Q1CWU5 CRISPR-associated protein Cas1 n=1 Tax=Myxococcu...   204   3e-51
UniRef50_C0BZ41 Putative uncharacterized protein n=3 Tax=Clostri...   204   4e-51
UniRef50_B0K547 CRISPR-associated protein Cas1 n=12 Tax=Bacteria...   203   6e-51
UniRef50_O57912 Putative uncharacterized protein PH0173 n=1 Tax=...   202   9e-51
UniRef50_A1A2M8 CRISPR-associated DNA polymerase n=14 Tax=Bacter...   202   1e-50
UniRef50_A7HNI6 CRISPR-associated protein Cas1 n=1 Tax=Fervidoba...   202   1e-50
UniRef50_C9LM09 CRISPR-associated protein Cas1 n=1 Tax=Dialister...   201   3e-50
UniRef50_Q2SIC8 CRISPR-associated protein Cas1 n=6 Tax=Gammaprot...   200   4e-50
UniRef50_B1X158 DUF48-containing protein n=12 Tax=Cyanobacteria ...   200   5e-50
UniRef50_A1BI39 CRISPR-associated protein Cas1 n=5 Tax=Chlorobia...   199   1e-49
UniRef50_C2GEC7 Crispr-associated protein Cas1 n=2 Tax=Corynebac...   198   2e-49
UniRef50_Q2RY11 CRISPR-associated protein, Cas1 family / CRISPR-...   198   2e-49
UniRef50_C0QR16 Crispr-associated protein Cas1 n=23 Tax=Bacteria...   198   2e-49
UniRef50_D0LSW9 CRISPR-associated protein Cas1 n=1 Tax=Haliangiu...   198   2e-49
UniRef50_A7HMV0 CRISPR-associated protein Cas1 n=3 Tax=Thermotog...   198   3e-49
UniRef50_A1HM55 CRISPR-associated protein Cas1 n=2 Tax=Thermosin...   197   6e-49
UniRef50_A5D0Y0 Uncharacterized protein n=40 Tax=cellular organi...   196   8e-49
UniRef50_A9AYP8 CRISPR-associated protein Cas1 n=1 Tax=Herpetosi...   195   1e-48
UniRef50_C1XWQ6 CRISPR-associated protein, Cas1 family n=3 Tax=T...   195   1e-48
UniRef50_A5UXM3 CRISPR-associated protein, Cas1 family n=4 Tax=C...   195   1e-48
UniRef50_C9M4Y8 CRISPR-associated protein Cas1 n=1 Tax=Jonquetel...   195   1e-48
UniRef50_D1BQ37 CRISPR-associated protein Cas1 n=1 Tax=Veillonel...   195   2e-48
UniRef50_C0A724 CRISPR-associated Cas1/Cas4 family protein n=1 T...   195   2e-48
UniRef50_Q3B3C1 CRISPR-associated protein, Cas1 family n=20 Tax=...   195   2e-48
UniRef50_C5BP90 CRISPR-associated protein Cas1 n=3 Tax=Gammaprot...   195   2e-48
UniRef50_A4J500 CRISPR-associated protein Cas1 n=1 Tax=Desulfoto...   195   2e-48
UniRef50_A2SRR7 CRISPR-associated protein, Cas1 family n=24 Tax=...   194   3e-48
UniRef50_C7G6C1 CRISPR-associated protein Cas1 n=3 Tax=Firmicute...   194   3e-48
UniRef50_C4FMU2 Putative uncharacterized protein n=1 Tax=Veillon...   193   6e-48
UniRef50_Q3J7J6 CRISPR-associated protein, Cas1 family n=2 Tax=N...   193   6e-48
UniRef50_B2RM83 CRISPR-associated protein Cas1 n=3 Tax=Bacteroid...   192   9e-48
UniRef50_Q1Q3I6 Putative uncharacterized protein n=1 Tax=Candida...   192   1e-47
UniRef50_UPI000197AF65 hypothetical protein BACCOPRO_02409 n=1 T...   192   1e-47
UniRef50_C1XN81 CRISPR-associated protein Cas1 n=2 Tax=Meiotherm...   192   2e-47
UniRef50_B4W4R1 CRISPR-associated protein Cas1 n=1 Tax=Microcole...   191   2e-47
UniRef50_Q8F1F5 Putative uncharacterized protein n=2 Tax=Leptosp...   191   3e-47
UniRef50_B9LWK7 CRISPR-associated protein Cas1 n=4 Tax=Halobacte...   191   3e-47
UniRef50_D0KYZ2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria ...   190   6e-47
UniRef50_O66692 Putative uncharacterized protein n=2 Tax=Aquific...   189   9e-47
UniRef50_B8DWG2 CRISPR-associated protein Cas1 n=4 Tax=Bifidobac...   189   9e-47
UniRef50_Q2NH78 Putative uncharacterized protein n=1 Tax=Methano...   189   1e-46
UniRef50_B0JKW9 CRISPR-associated protein Cas1 n=6 Tax=Cyanobact...   189   1e-46
UniRef50_Q2FQQ2 CRISPR-associated protein Cas1 n=2 Tax=Methanomi...   189   1e-46
UniRef50_B7KM77 CRISPR-associated protein Cas1 n=1 Tax=Cyanothec...   189   2e-46
UniRef50_Q8YWX6 Alr1468 protein n=4 Tax=Cyanobacteria RepID=Q8YW...   187   3e-46
UniRef50_B7GYY4 CRISPR-associated protein Cas1 n=8 Tax=Proteobac...   187   3e-46
UniRef50_Q1J1U7 CRISPR-associated protein Cas1 n=1 Tax=Deinococc...   187   3e-46
UniRef50_B2SPB2 Crispr-associated protein Cas1 n=56 Tax=Bacteria...   186   7e-46
UniRef50_Q53W21 Putative uncharacterized protein TTHB145 n=3 Tax...   186   9e-46
UniRef50_B9M5J4 CRISPR-associated protein Cas1 n=9 Tax=Bacteria ...   185   2e-45
UniRef50_C0FSR1 Putative uncharacterized protein n=1 Tax=Rosebur...   184   2e-45
UniRef50_B7C8S2 Putative uncharacterized protein n=2 Tax=Eubacte...   184   3e-45
UniRef50_Q6L317 DNA polymerase n=2 Tax=Thermoplasmatales RepID=Q...   184   3e-45
UniRef50_C6CA70 CRISPR-associated protein Cas1 n=56 Tax=Bacteria...   184   3e-45
UniRef50_Q0AW57 CRISPR-associated protein, Cas1 family n=1 Tax=S...   183   4e-45
UniRef50_B8G918 CRISPR-associated protein Cas1 n=5 Tax=Chlorofle...   183   5e-45
UniRef50_A4X3M4 CRISPR-associated protein, Cas1 family n=4 Tax=A...   182   1e-44
UniRef50_C9RRG3 CRISPR-associated protein Cas1 n=1 Tax=Fibrobact...   182   2e-44
UniRef50_B5IHG3 CRISPR-associated protein Cas1 n=3 Tax=Acidulipr...   181   2e-44
UniRef50_UPI0000F51762 hypothetical protein Faci_00015 n=1 Tax=F...   181   2e-44
UniRef50_Q65S18 Putative uncharacterized protein n=1 Tax=Mannhei...   181   2e-44
UniRef50_C7RP03 CRISPR-associated protein Cas1 n=1 Tax=Candidatu...   180   4e-44
UniRef50_A4FJX8 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Sacc...   180   4e-44
UniRef50_D1N0J7 CRISPR-associated protein Cas1 n=1 Tax=Victivall...   180   5e-44
UniRef50_D0MJ58 CRISPR-associated protein Cas1 n=1 Tax=Rhodother...   179   1e-43
UniRef50_C8Q0H7 CRISPR-associated protein Cas1 n=6 Tax=Proteobac...   179   1e-43
UniRef50_UPI0001C41A73 CRISPR-associated protein Cas1-2 n=1 Tax=...   178   2e-43
UniRef50_D1VVR4 CRISPR-associated endonuclease Cas1, DVULG subty...   178   2e-43
UniRef50_A9BUF1 CRISPR-associated protein Cas1 n=33 Tax=Proteoba...   178   2e-43
UniRef50_Q6L363 DNA polymerase n=1 Tax=Picrophilus torridus RepI...   178   2e-43
UniRef50_B7A8Y4 CRISPR-associated protein Cas1 n=1 Tax=Thermus a...   177   4e-43
UniRef50_B8GSH8 CRISPR-associated protein Cas1 n=1 Tax=Thioalkal...   176   9e-43
UniRef50_C8W3G7 CRISPR-associated protein Cas1 n=24 Tax=Bacteria...   176   9e-43
UniRef50_Q74N45 NEQ017 n=1 Tax=Nanoarchaeum equitans RepID=Q74N4...   175   1e-42
UniRef50_Q8YZS6 Alr0381 protein n=6 Tax=Cyanobacteria RepID=Q8YZ...   175   2e-42
UniRef50_Q2LQX3 Uncharacterized protein predicted to be involved...   173   5e-42
UniRef50_B9LX94 CRISPR-associated protein Cas1 n=2 Tax=Halobacte...   173   5e-42
UniRef50_D0MKP4 CRISPR-associated protein Cas1 n=1 Tax=Rhodother...   173   9e-42
UniRef50_D2LF35 CRISPR-associated protein Cas1 n=1 Tax=Rhodomicr...   172   1e-41
UniRef50_C7NA04 CRISPR-associated protein Cas1 n=1 Tax=Leptotric...   171   2e-41
UniRef50_A1BI46 CRISPR-associated protein Cas1 n=2 Tax=Chlorobia...   171   2e-41
UniRef50_A9AX66 CRISPR-associated protein Cas1 n=1 Tax=Herpetosi...   171   2e-41
UniRef50_Q2J7N9 CRISPR-associated protein Cas1 n=1 Tax=Frankia s...   171   3e-41
UniRef50_A9GDF7 Putative uncharacterized protein n=1 Tax=Sorangi...   170   4e-41
UniRef50_B3EG05 CRISPR-associated protein Cas1 n=11 Tax=Bacteria...   170   4e-41
UniRef50_Q0ADY5 CRISPR-associated protein, Cas1 family n=2 Tax=N...   170   7e-41
UniRef50_Q2FL78 CRISPR-associated protein, Cas1 family n=1 Tax=M...   169   1e-40
UniRef50_B8CYA1 CRISPR-associated protein Cas1 n=2 Tax=cellular ...   169   1e-40
UniRef50_A0LHZ4 CRISPR-associated protein, Cas1 family n=2 Tax=D...   168   1e-40
UniRef50_B0TFX3 Crispr-associated protein cas1 n=4 Tax=Clostridi...   168   1e-40
UniRef50_C8WTR3 CRISPR-associated protein Cas1 n=2 Tax=Alicyclob...   168   2e-40
UniRef50_A7GY67 Crispr-associated protein Cas1 n=6 Tax=Campyloba...   166   7e-40
UniRef50_Q96X75 Putative uncharacterized protein ST2634 n=1 Tax=...   165   1e-39
UniRef50_A8UXX8 Putative uncharacterized protein n=1 Tax=Hydroge...   165   2e-39
UniRef50_D0W646 CRISPR-associated protein Cas1 n=1 Tax=Neisseria...   165   2e-39
UniRef50_A4FXZ8 CRISPR-associated protein, Cas1 family n=9 Tax=c...   165   2e-39
UniRef50_B5YJS2 Crispr-associated protein Cas1 n=1 Tax=Thermodes...   164   3e-39
UniRef50_A7NP58 CRISPR-associated protein Cas1 n=6 Tax=Chlorofle...   163   9e-39
UniRef50_A7BYC5 Protein containing DUF48 n=1 Tax=Beggiatoa sp. P...   163   9e-39
UniRef50_A6UNF5 CRISPR-associated protein Cas1 n=1 Tax=Methanoco...   163   9e-39
UniRef50_B0VIK5 Putative uncharacterized protein n=1 Tax=Candida...   162   1e-38
UniRef50_B6IX22 CRISPR-associated protein Cas1, putative n=2 Tax...   162   2e-38
UniRef50_C0QHV1 Putative CRISPR-associated protein (Uncharacteri...   160   6e-38
UniRef50_A5UJ50 Uncharacterized protein predicted to be involved...   159   9e-38
UniRef50_Q03KT5 CRISPR-associated protein, Cas1 family n=5 Tax=S...   159   1e-37
UniRef50_P71636 CRISPR-associated protein Cas1 n=11 Tax=Mycobact...   159   1e-37
UniRef50_O28401 Putative uncharacterized protein n=1 Tax=Archaeo...   158   2e-37
UniRef50_C3MWK6 CRISPR-associated protein Cas1 n=6 Tax=Sulfolobu...   157   4e-37
UniRef50_B8GDW2 CRISPR-associated protein Cas1 n=1 Tax=Methanosp...   157   5e-37
UniRef50_C3MX12 CRISPR-associated protein Cas1 n=11 Tax=Sulfolob...   157   6e-37
UniRef50_B1YCK7 CRISPR-associated protein Cas1 n=2 Tax=Thermopro...   155   2e-36
UniRef50_C9LGP6 CRISPR-associated protein Cas1 n=3 Tax=Prevotell...   155   2e-36
UniRef50_Q1CW50 CRISPR-associated fusion protein Cas4/Cas1 n=5 T...   154   3e-36
UniRef50_C5SD37 CRISPR-associated protein Cas1 n=1 Tax=Allochrom...   153   9e-36
UniRef50_A3XI90 Putative uncharacterized protein n=1 Tax=Leeuwen...   152   1e-35
UniRef50_A8ABK8 CRISPR-associated protein Cas1 n=1 Tax=Ignicoccu...   152   2e-35
UniRef50_C0W0W5 CRISPR-associated Cas1 family protein n=1 Tax=Ac...   151   3e-35
UniRef50_Q2FPW6 CRISPR-associated protein Cas1 n=1 Tax=Methanosp...   149   1e-34
UniRef50_A6UVX9 CRISPR-associated protein Cas1 n=2 Tax=Methanoco...   149   1e-34
UniRef50_C8PKY6 Putative CRISPR-associated protein Cas1 n=1 Tax=...   148   2e-34
UniRef50_D2QT50 CRISPR-associated protein Cas1 n=1 Tax=Spirosoma...   148   2e-34
UniRef50_A1WUP2 CRISPR-associated protein Cas1 n=1 Tax=Halorhodo...   148   3e-34
UniRef50_D0YU98 Crispr-associated protein Cas1 n=1 Tax=Mobiluncu...   147   6e-34
UniRef50_A3CTI4 CRISPR-associated protein Cas1 n=1 Tax=Methanocu...   146   8e-34
UniRef50_C8N6V7 Putative uncharacterized protein n=1 Tax=Cardiob...   146   1e-33
UniRef50_B3PMY9 Putative uncharacterized protein n=1 Tax=Mycopla...   145   2e-33
UniRef50_B4ATI8 Crispr-associated protein Cas1 n=5 Tax=Proteobac...   145   2e-33
UniRef50_UPI0001BCCAFD hypothetical protein SnoxA4_00467 n=1 Tax...   145   2e-33
UniRef50_B8D4S7 CRISPR-associated protein Cas1 n=1 Tax=Desulfuro...   142   2e-32
UniRef50_A6DE79 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Cami...   142   2e-32
UniRef50_A3DLB7 CRISPR-associated protein, Cas1 family n=1 Tax=S...   142   2e-32
UniRef50_Q8F874 Putative uncharacterized protein n=1 Tax=Leptosp...   141   3e-32
UniRef50_A7I668 CRISPR-associated protein Cas1 n=1 Tax=Candidatu...   140   5e-32
UniRef50_A3MVN2 CRISPR-associated protein, Cas1 family n=4 Tax=T...   140   5e-32
UniRef50_D2QAN8 CRISPR-associated protein Cas1 n=2 Tax=Bifidobac...   140   6e-32
UniRef50_C6I8L1 CRISPR-associated protein n=1 Tax=Bacteroides sp...   140   7e-32
UniRef50_A0LWB2 CRISPR-associated protein Cas1 n=1 Tax=Acidother...   138   2e-31
UniRef50_Q7MRD4 Putative uncharacterized protein n=1 Tax=Wolinel...   138   2e-31
UniRef50_A1WH94 CRISPR-associated protein, Cas1 family n=5 Tax=P...   138   2e-31
UniRef50_B5IAF4 CRISPR-associated protein Cas1 n=3 Tax=Euryarcha...   138   2e-31
UniRef50_A3ZPG0 Putative uncharacterized protein n=1 Tax=Blastop...   137   4e-31
UniRef50_D2R8Z2 CRISPR-associated protein Cas1 n=1 Tax=Pirellula...   137   5e-31
UniRef50_Q7MTH7 CRISPR-associated protein Cas1 n=3 Tax=Porphyrom...   135   1e-30
UniRef50_B1GZM4 CRISPR-associated protein Cas1 n=1 Tax=unculture...   135   2e-30
UniRef50_Q9YCL8 Putative CRISPR-associated protein Cas1 n=1 Tax=...   135   2e-30
UniRef50_Q1WVJ8 CRISPR-associated protein n=1 Tax=Lactobacillus ...   134   4e-30
UniRef50_A1ZHZ5 Crispr-associated protein Cas1 n=1 Tax=Microscil...   134   4e-30
UniRef50_Q8TVS6 Uncharacterized conserved protein n=1 Tax=Methan...   134   4e-30
UniRef50_B1L400 CRISPR-associated protein Cas1 n=2 Tax=Archaea R...   133   6e-30
UniRef50_Q5X8T5 Putative uncharacterized protein n=1 Tax=Legione...   133   6e-30
UniRef50_C9RJP2 CRISPR-associated protein Cas1 n=21 Tax=cellular...   132   2e-29
UniRef50_A2SQK9 Uncharacterized protein predicted to be involved...   131   2e-29
UniRef50_A2BKJ8 Universally conserved protein n=1 Tax=Hypertherm...   131   2e-29
UniRef50_B2KB47 CRISPR-associated protein Cas1 n=2 Tax=Elusimicr...   131   2e-29
UniRef50_B9M9X7 Putative uncharacterized protein n=1 Tax=Diaphor...   131   3e-29
UniRef50_C7V674 Predicted protein n=2 Tax=Enterococcus faecalis ...   131   3e-29
UniRef50_Q13CC1 CRISPR-associated protein, Cas1 family n=2 Tax=R...   130   5e-29
UniRef50_B2UP48 CRISPR-associated protein Cas1 n=1 Tax=Akkermans...   130   5e-29
UniRef50_A8TI31 CRISPR-associated protein Cas1 n=1 Tax=Methanoco...   130   7e-29
UniRef50_A8LN06 CRISPR-associated protein Cas1 n=2 Tax=Rhodobact...   129   1e-28
UniRef50_A6DE65 Putative uncharacterized protein n=1 Tax=Caminib...   128   2e-28
UniRef50_A6VLA8 CRISPR-associated protein Cas1 n=13 Tax=Proteoba...   128   2e-28
UniRef50_C0WRP8 CRISPR-associated protein n=18 Tax=Lactobacillac...   127   6e-28
UniRef50_B4AQ39 Crispr-associated protein Cas1 n=5 Tax=Francisel...   126   9e-28
UniRef50_C6MJ62 CRISPR-associated protein Cas1 n=5 Tax=Nitrosomo...   125   2e-27
UniRef50_Q03LF6 CRISPR-associated protein, Cas1 family n=6 Tax=S...   124   3e-27
UniRef50_C3WD45 CRISPR-associated protein cas1 n=1 Tax=Fusobacte...   123   7e-27
UniRef50_C6HZN2 CRISPR-associated protein Cas1 n=1 Tax=Leptospir...   123   1e-26
UniRef50_B3W9S5 CRISPR-associated protein n=4 Tax=Lactobacillus ...   120   8e-26
UniRef50_B3E1C9 CRISPR-associated protein Cas1 n=1 Tax=Methylaci...   118   3e-25
UniRef50_C7XMU1 CRISPR-associated protein cas1 n=2 Tax=Fusobacte...   116   9e-25
UniRef50_UPI00016B206F hypothetical protein cdiviTM7_00753 n=1 T...   115   3e-24
UniRef50_A8REI1 Putative uncharacterized protein n=2 Tax=unclass...   114   4e-24
UniRef50_A8ABE8 CRISPR-associated protein Cas1 n=1 Tax=Ignicoccu...   114   4e-24
UniRef50_A7HP88 CRISPR-associated protein Cas1 n=1 Tax=Parvibacu...   114   5e-24
UniRef50_Q5LZX6 Putative uncharacterized protein n=2 Tax=Strepto...   113   8e-24
UniRef50_B5ZLL1 CRISPR-associated protein Cas1 n=2 Tax=Gluconace...   113   8e-24
UniRef50_D2PIT7 CRISPR-associated protein Cas1 n=2 Tax=Sulfolobu...   105   2e-21
UniRef50_A1RZT8 CRISPR-associated protein Cas1 n=1 Tax=Thermofil...   103   6e-21
UniRef50_C5EZ73 Crispr-protein cas1 n=1 Tax=Helicobacter pulloru...    92   3e-17

Sequences not found previously or not previously below threshold:

UniRef50_Q57823 Uncharacterized protein MJ0378 n=20 Tax=Euryarch...   185   2e-45
UniRef50_UPI000174611D CRISPR-associated protein Cas1/Cas4 n=1 T...   173   5e-42
UniRef50_B0VHC1 Putative uncharacterized protein n=1 Tax=Candida...   164   4e-39
UniRef50_C5EH11 Crispr-protein cas1 n=1 Tax=Clostridiales bacter...   159   1e-37
UniRef50_B8I084 CRISPR-associated protein Cas1 n=1 Tax=Clostridi...   123   7e-27
UniRef50_C0WE67 Crispr-associated protein n=1 Tax=Acidaminococcu...   123   1e-26
UniRef50_C7G696 CRISPR-associated protein Cas1 n=2 Tax=Roseburia...   122   2e-26
UniRef50_A9GQD8 Putative uncharacterized protein n=1 Tax=Sorangi...   121   2e-26
UniRef50_Q03JI7 CRISPR-associated protein, Cas1 family n=40 Tax=...   116   7e-25
UniRef50_C2EF73 CRISPR-associated Cas1 family protein n=1 Tax=La...   116   1e-24
UniRef50_C8PNV3 CRISPR-associated protein Cas1 n=1 Tax=Treponema...   115   2e-24
UniRef50_Q6KIQ8 Conserved expressed putative DNA-repair protein ...   113   9e-24
UniRef50_B1BJM4 Crispr-associated protein Cas1 n=2 Tax=Clostridi...   113   1e-23
UniRef50_Q5HK87 CRISPR-associated protein Cas1 n=1 Tax=Staphyloc...   112   2e-23
UniRef50_D1AUW5 CRISPR-associated protein Cas1 n=1 Tax=Streptoba...   111   3e-23
UniRef50_C2CKI7 CRISPR associated protein n=1 Tax=Anaerococcus t...   110   6e-23
UniRef50_Q5HSQ9 CRISPR-associated protein Cas1 n=12 Tax=Campylob...   109   1e-22
UniRef50_C4ZA17 Putative uncharacterized protein n=2 Tax=Eubacte...   105   2e-21
UniRef50_UPI0001977683 putative CRISPR-associated protein n=1 Ta...   104   5e-21
UniRef50_Q73QW5 CRISPR-associated protein Cas1 n=7 Tax=Bacteria ...   102   1e-20
UniRef50_A7BYT7 Putative uncharacterized protein n=1 Tax=Beggiat...   101   4e-20
UniRef50_C5NZ03 CRISPR-associated protein Cas1 n=2 Tax=Firmicute...   100   8e-20
UniRef50_D0WRI5 CRISPR-associated protein Cas1, NMENI subtype n=...    99   2e-19
UniRef50_Q4A5I1 Putative uncharacterized protein n=5 Tax=Mycopla...    98   5e-19
UniRef50_C5F1H0 Crispr-protein cas1 n=1 Tax=Helicobacter pulloru...    97   8e-19
UniRef50_B9CMG3 CRISPR-associated protein Cas1, NMENI subtype n=...    85   3e-15

>UniRef50_Q46896 Uncharacterized protein ygbT n=119 Tax=cellular organisms
           RepID=YGBT_ECOLI
          Length = 305

 Score =  326 bits (835), Expect = 9e-88,   Method: Composition-based stats.
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60
           MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV
Sbjct: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60

Query: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120
           SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF
Sbjct: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120

Query: 121 ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180
           ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI
Sbjct: 121 ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP 240
           SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP
Sbjct: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP 240

Query: 241 GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA 300
           GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA
Sbjct: 241 GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDA 300

Query: 301 GHRSS 305
           GHRSS
Sbjct: 301 GHRSS 305


>UniRef50_D1NTI3 CRISPR-associated protein Cas1 n=10 Tax=Bacteria RepID=D1NTI3_9BIFI
          Length = 366

 Score =  305 bits (781), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 106/296 (35%), Positives = 162/296 (54%), Gaps = 4/296 (1%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVR 66
             +  +DR++ ++ ++  ++  + A  + D  G+R HIP  +++ +ML PGT V+H A+ 
Sbjct: 32  ELVRCEDRLTFLYFEHCVVNRDNNAITVTDDRGVR-HIPAAALSVLMLGPGTSVTHQAMM 90

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
           +    G  ++WVGE GVR Y SG+P    S+ L  QA+L  +   RL V R M+ +RF  
Sbjct: 91  VIGDNGATVIWVGERGVRTYCSGKPLTHSSNLLQKQAQLVTNMRKRLSVARAMYAMRFPH 150

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
              +  +++QLRG EG+RVR  Y   +KQ GV W  R Y P+D+   D INQ +SAA  C
Sbjct: 151 EDVSNLTMQQLRGREGARVRRVYRHWSKQTGVRWERRDYRPEDFADSDRINQALSAANIC 210

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDRE 246
           LYG+  A I+A G +P +GFVHTG  LSFVYD+AD+ K +  +P AF+ A     +    
Sbjct: 211 LYGIAHAVIVALGCSPGLGFVHTGHELSFVYDMADLYKAELSIPVAFKTAATEVDDIGGA 270

Query: 247 VRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP---EDAQPVAIPLPVSLGD 299
           VR A RD       + +++  I  +  A + +         D +   +    S GD
Sbjct: 271 VRRAMRDAMYDLSIMPRMVKDIHHLFDAADAENEGNNLYLWDGKEGTVEAGRSYGD 326


>UniRef50_D1A5U2 CRISPR-associated protein Cas1 n=3 Tax=Actinomycetales
           RepID=D1A5U2_THECD
          Length = 315

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 104/297 (35%), Positives = 154/297 (51%), Gaps = 7/297 (2%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + DR+S I+L+   +   D A    D  G  THIP  ++ C++L PGTRV+H A
Sbjct: 12  PRELTRMSDRISFIYLERCTLHREDNAITAEDADG-ITHIPSATIGCLLLGPGTRVTHQA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + +    G  +VWVGE GVR Y+ G+     S  +  QA    +   RL+V R M+ +RF
Sbjct: 71  MSVLGDSGAGVVWVGEQGVRFYSGGRSLTRSSALVEAQAIKWANRRTRLEVARAMYRMRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +  PA  + ++L G EG RV+  Y   A +YG+TW GR Y P D+   D +NQ ++AA 
Sbjct: 131 PDEDPAGLTRQELLGREGRRVKERYRQEAAKYGITWKGRHYIPGDFGSSDPVNQAVTAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C+YG+ +  + A G +P +GF+H+G  L+FV DIAD+ K +  +P AF     +P +  
Sbjct: 191 QCMYGIAQTTVAALGCSPGLGFIHSGHELAFVLDIADLYKTEFALPIAFRTVAESPEDVG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAG 301
              R A RD       L + +  I+ +L       P  P+D     I      GD G
Sbjct: 251 SRTRRAIRDEVNRVGLLRRCVDDIKSLL------LPDVPDDPLNSDIDQVTLQGDHG 301


>UniRef50_D1CAI8 CRISPR-associated protein Cas1 n=3 Tax=Bacteria RepID=D1CAI8_SPHTD
          Length = 314

 Score =  292 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 120/311 (38%), Positives = 180/311 (57%), Gaps = 14/311 (4%)

Query: 4   LPLNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           + L+ +P ++D  S +++++ +I+    A  + D  G+   +P  S+  +ML PGT +SH
Sbjct: 1   MDLHILPKVRDSWSYLYVEHARIEQEAKAIAIHDAVGM-VPVPCASLGILMLGPGTSISH 59

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
           AA+R  A+ G L++W GE GVR YA G      +  L+ QA+L  D  LRL+VV +M+++
Sbjct: 60  AAIRTLAENGCLVLWTGEEGVRFYAQGLGETRSARNLMRQARLWADPALRLRVVFRMYQM 119

Query: 123 RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISA 182
           RF EP P   +++Q+RG+EG+RVR  YA  +++ GV W GR +  ++W   D IN+ +S 
Sbjct: 120 RFSEPLPPDLTLQQIRGMEGARVRDAYARASRETGVPWRGRSFQRRNWSATDPINRALSC 179

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           A SCLYG+  AAI++ GY+P +GF+HTGK LSFVYDIAD+ K    +P AF +      +
Sbjct: 180 ANSCLYGICHAAIVSLGYSPGLGFIHTGKMLSFVYDIADLYKATVTIPLAFRVVAEGTHD 239

Query: 243 PDREVRLACRDIFRSSKTLAKLIPLIEDVL----AAGEIQPPAPPEDAQ--------PVA 290
            +  VR ACRD F + + L  +   IE VL    A G    P   EDA           A
Sbjct: 240 LEGRVRRACRDAFVAHRLLGTIATDIEHVLDISDADGGADEPDFDEDAAYPGGLWDPSGA 299

Query: 291 IPLPVSLGDAG 301
           +   V+    G
Sbjct: 300 VAGGVNHAPEG 310


>UniRef50_Q2JWC7 CRISPR-associated protein Cas1 n=3 Tax=Chroococcales
           RepID=Q2JWC7_SYNJA
          Length = 315

 Score =  290 bits (743), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 112/303 (36%), Positives = 175/303 (57%), Gaps = 6/303 (1%)

Query: 2   TWLPLNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60
           T   L  IP ++D +S ++++  +I+    A  ++ + G    IP  S+  +ML PGT +
Sbjct: 6   TTKSLRSIPKVRDSISFVYVERCRIEQDAKAIAVLQEDGRYI-IPCASLTTLMLGPGTAI 64

Query: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120
           +HAA++  A     + WVGE G+R YASG    +  ++L +QAKL  D    ++VVR+M+
Sbjct: 65  THAAIKNLADGLCSVQWVGEDGLRFYASGSHPSSSVERLYHQAKLWADPVQHMEVVRRMY 124

Query: 121 ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180
             RF EP     ++EQ+RG+EG RVR  Y+ L+K+ GV W GR Y  K+WE  D +N+ +
Sbjct: 125 SFRFPEPLKEGLTLEQIRGLEGVRVRTVYSRLSKETGVNWKGRSYKLKEWECADPVNRAL 184

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNP 240
           S A +CLY V +AA+ A GY+ A+GF+H GKPLSFVYD+AD+ K +  +P AF+ A    
Sbjct: 185 SVANTCLYAVCQAALNAVGYSTALGFIHIGKPLSFVYDVADLYKTEITIPVAFKAAAELM 244

Query: 241 GEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVS 296
              +   R  CR+ F   + + ++I  ++ +L     Q  + P     D +  A+   VS
Sbjct: 245 PNFESRTRQLCREKFVEHRLMQRIIDDVDAILGFRATQEESSPVGSLWDNEKGAVEGGVS 304

Query: 297 LGD 299
            G+
Sbjct: 305 YGE 307


>UniRef50_C7QEM2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria RepID=C7QEM2_CATAD
          Length = 323

 Score =  289 bits (740), Expect = 9e-77,   Method: Composition-based stats.
 Identities = 95/307 (30%), Positives = 156/307 (50%), Gaps = 13/307 (4%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + DRVS ++L+   +     A    D  G  THIP  ++  ++L PGTR++H A
Sbjct: 12  PYQLPRIADRVSFVYLERCTVHRDANAITAQDADG-ITHIPSATIGTLLLGPGTRITHQA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + +    G  + WVGE G R YA+ +     S  +  QA L  +   RL + R M+ +RF
Sbjct: 71  MAVLGDCGANVAWVGEHGARFYAAARSLNRSSALVEAQATLWANRRTRLDIARAMYRMRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +  P+    +QL G+EG R++  Y   +++ GV W+GR+Y P ++  GD INQ I+AA 
Sbjct: 131 PDEDPSGFMRQQLLGMEGRRLKDCYRQQSQRTGVPWHGRQYTPGNFNAGDAINQAITAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C+YGV    I A G +P +GF+H+G  LSFV DIAD+ K +  +P AF+ A  +  +  
Sbjct: 191 QCMYGVAHTIITALGCSPGLGFIHSGHELSFVMDIADLYKTEIGIPVAFDTAAEDSTDIG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP------------EDAQPVAIP 292
              R A R+  R+++ L + +  ++ +L     +P +              +  +   + 
Sbjct: 251 PRTRRALREQIRTTRLLERCVDDVKALLTTPNNEPGSSDATDTGFFDQVQLQSDRETEVE 310

Query: 293 LPVSLGD 299
              +  D
Sbjct: 311 GGRNYAD 317


>UniRef50_D1CGD6 CRISPR-associated protein Cas1 n=7 Tax=cellular organisms
           RepID=D1CGD6_THET1
          Length = 324

 Score =  285 bits (730), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 124/299 (41%), Positives = 175/299 (58%), Gaps = 5/299 (1%)

Query: 1   MTWLPLNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTR 59
           M    L+ +P + D  S +++++ +ID    A  L D TG    +P  S++ +ML PGT 
Sbjct: 1   MRLKDLHILPRVSDSWSYLYVEHCRIDQDARAISLHDATGKTM-VPCASLSLLMLGPGTS 59

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM 119
           ++HAA++  A  G L+ WVGE GVR YA G      +   L QA L  D +L L+VVR+M
Sbjct: 60  ITHAAIQTLADNGCLVAWVGEEGVRFYAQGMGETRSATNTLRQAMLWSDPELHLQVVRRM 119

Query: 120 FELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQC 179
           +E+RF  P     S++Q+RG+EG+RVR  Y  L+++ GV W GR Y  K W   D IN+ 
Sbjct: 120 YEIRFRHPINPNTSLKQIRGMEGARVRGAYLQLSRETGVEWKGRDYSSKSWHSNDAINRA 179

Query: 180 ISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRN 239
           ISAA SCLYGV  AAI++AGY+ A+GF+HTGK LSFVYD+AD+ K +  +P AF      
Sbjct: 180 ISAANSCLYGVCHAAIVSAGYSTALGFIHTGKMLSFVYDVADLYKTEISMPAAFYAVAEG 239

Query: 240 PGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLG 298
               +  VR  CRDI R ++ LA+++  I+ VL    +  P P +   P      V  G
Sbjct: 240 GASLESRVRRKCRDILRETRLLARIVEDIDTVL---NVDSPIPHKYQNPYDSDPGVPGG 295


>UniRef50_B4V4P5 Crispr-associated protein cas1 n=4 Tax=Streptomyces
           RepID=B4V4P5_9ACTO
          Length = 315

 Score =  285 bits (729), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 101/301 (33%), Positives = 155/301 (51%), Gaps = 7/301 (2%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + +R+S ++L+   +     A    D  G  THIP  ++  ++L PGTR++H A
Sbjct: 12  PRELTRVAERISFVYLERCVVHRDANAITAEDADGT-THIPSATIGTLLLGPGTRITHQA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + + A+ G  + WVGE GVR YA G+     S  +  QA L  +   RL+V R M+ LRF
Sbjct: 71  MSVLAESGAAVAWVGEQGVRYYAGGRALSRSSALVEAQATLWANRRTRLEVARAMYRLRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +  P+  +  +L G EG RV+  Y   A + GV W GR Y P D+  GD  NQ ++AA 
Sbjct: 131 PDEDPSGLTRRELLGHEGYRVKECYRHQADRTGVPWRGRHYVPGDFTAGDAPNQAVTAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C+YG+  A + A G A  +GFVH+G  LSFV D+AD+ K +  +P AF++A  +  +  
Sbjct: 191 QCMYGIAHAVVAALGCATGLGFVHSGHELSFVLDVADLYKTEIGIPVAFDVAAESTEDIG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPED------AQPVAIPLPVSLG 298
              R A RD    ++ L + +  I+ +L        +  +D         VA+P   +  
Sbjct: 251 SRTRRALRDAVNKNRLLDRCVNDIKLLLQPEGPGAASAADDVVMLESDSGVAVPAGRNYA 310

Query: 299 D 299
           D
Sbjct: 311 D 311


>UniRef50_C1YVP5 CRISPR-associated protein Cas1 n=1 Tax=Nocardiopsis dassonvillei
           subsp. dassonvillei DSM 43111 RepID=C1YVP5_NOCDA
          Length = 327

 Score =  284 bits (726), Expect = 3e-75,   Method: Composition-based stats.
 Identities = 102/302 (33%), Positives = 148/302 (49%), Gaps = 6/302 (1%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           P     + +R+S ++L+   +     A    D  G R  +P  ++  ++L PGT V+H+A
Sbjct: 12  PRELTRVGERLSFLYLERCVVHRDSNAITAEDGDGTRY-LPSATIGTLLLGPGTNVTHSA 70

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           + L  + G  +VWVGE GVR YA+G+     S  +  QA    +   RL V R M+ +RF
Sbjct: 71  MSLLGECGATVVWVGEHGVRYYAAGRALTRSSRLVEAQATAWANRRSRLDVARAMYRMRF 130

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +      S + L G EG RV+A Y   A + GVTW GRRY P D +  D  N+ I+AA 
Sbjct: 131 PDLDVEALSRQALLGKEGDRVKACYREQAARTGVTWRGRRYVPGDHDVSDPPNKAITAAA 190

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
            C YGV  A   A G +P +GFVH+G    FV D+AD+ K +  +P AF+ A +   + D
Sbjct: 191 QCFYGVAHAVTAALGCSPGLGFVHSGHERGFVMDVADLYKVEIGIPVAFDAAAQGDEDVD 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIED-VLAAGEIQPPAPPEDAQPVAIPLPVS----LGD 299
              R   RD       L + +  I+  +L  G +      EDA   A          +GD
Sbjct: 251 GVTRRLLRDRINEEGLLERCVRDIKALLLGEGSVGAQGEAEDAGESANDDVADTVGLVGD 310

Query: 300 AG 301
            G
Sbjct: 311 RG 312


>UniRef50_D2RB04 CRISPR-associated endonuclease Cas1, ECOLI subtype n=3 Tax=Bacteria
           RepID=D2RB04_GARVA
          Length = 313

 Score =  283 bits (724), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 105/296 (35%), Positives = 166/296 (56%), Gaps = 7/296 (2%)

Query: 10  PLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
            + DRVS I++++ +I+ +D A  + D  G    +P   +  ++L PGT ++H A+ L  
Sbjct: 17  RISDRVSFIYVEHAKINRLDSAVTVFDANGTI-RVPAAMIGVLLLGPGTEITHRAMELLG 75

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP 129
            VG  +VWVGE GVR YA G+     S  L  Q+KL  +   RL V RKM+++RF     
Sbjct: 76  DVGASIVWVGEHGVRNYAHGRALSRSSRLLEKQSKLVTNSRSRLNVARKMYQMRFPNENV 135

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
           +  +++QLRG EG+RVR  Y  ++ +Y V WNGR Y   D+E G  +N+ +S    CLYG
Sbjct: 136 SSYTLQQLRGREGARVRHLYREMSNKYNVQWNGRDYKVNDFESGTVVNKALSVGNVCLYG 195

Query: 190 VTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR--NPGEPDREV 247
           +  + I A G AP +GFVHTG  LS VYDIAD+ K +  +P +FEIA R  +  + ++ +
Sbjct: 196 LVHSIISALGLAPGLGFVHTGHDLSLVYDIADLYKAELTIPASFEIAARCESDDDIEQLM 255

Query: 248 RLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVSLGD 299
           RL  RD F +   +++++  I+++L                D + + +   V+  +
Sbjct: 256 RLKMRDCFANCNIMSRIVNDIQNLLEIPIDDQITVDVIHLWDDKELLVASGVNYSE 311


>UniRef50_C7LYW4 CRISPR-associated protein Cas1 n=1 Tax=Acidimicrobium ferrooxidans
           DSM 10331 RepID=C7LYW4_ACIFD
          Length = 314

 Score =  281 bits (718), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 100/296 (33%), Positives = 162/296 (54%), Gaps = 5/296 (1%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVR 66
              P+  R S ++L++  +     A V + ++G  T++P  +V  ++L PGTR++H A+ 
Sbjct: 17  ELQPVSRRSSFVYLEHCVVHRDANAVVSVTESGT-TYLPAAAVGTLLLGPGTRITHQAML 75

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
           L  + G ++ WVGE   R+YA        +  L  QA+L  +   RL+V R+M+++RF  
Sbjct: 76  LLGESGVVVCWVGEGDTRLYAWAPSLFQSTRFLEAQARLVSNRQDRLRVARQMYQMRFPG 135

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
              ++ ++++LRG+EG+R+R TY  LA  +G+ W+GR YDP +   GD +N+ +S A S 
Sbjct: 136 EDVSKATMQRLRGMEGARIRRTYRHLASAFGIDWHGRHYDPNNSSAGDDVNRALSIANSV 195

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDRE 246
           LYGV   AI+A G +P +GFVHTG  LSFVYD+AD+ K +  +P AFE A +  G    +
Sbjct: 196 LYGVVHTAIVALGCSPGLGFVHTGHSLSFVYDVADLYKVELAIPVAFEAAAQRTGSLSSQ 255

Query: 247 VRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVSLG 298
           VR   R+    +  L + +  I  +L   +      P     D +   +P      
Sbjct: 256 VRRTMRERIHEAHLLERAVDDIRLLLGTPDADLGGEPGLVLFDDRIGEVPAGTDYS 311


>UniRef50_B1VIX8 CRISPR-associated protein n=6 Tax=Corynebacterium
           RepID=B1VIX8_CORU7
          Length = 312

 Score =  279 bits (715), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 93/271 (34%), Positives = 154/271 (56%), Gaps = 1/271 (0%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           + DR+S ++++   +     A  + D+ G   H+P   +A ++L  GTR+++AA+ L   
Sbjct: 17  MGDRISFLYVERAVVSRDGNALTITDQRG-VAHVPATQLAVLLLGTGTRITNAAMALLGD 75

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            G   VWVGE GVR YA G+P    S     QA++  ++  RL+  R+M+ LRF     +
Sbjct: 76  CGVSTVWVGERGVRYYAHGRPPAKSSRLAELQARVVTNQRKRLECARRMYGLRFPGEDVS 135

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
           + ++ QLRG EG+R++  YA  AK+ GV WN RRYDP D++  D INQ ++  ++ LYG+
Sbjct: 136 KLTMAQLRGREGARMKRLYAAEAKRTGVAWNRRRYDPNDYDSSDPINQALTTGSAALYGI 195

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
             A I+  G+ PA+G +HTG   SFVYD+AD+ K +  +P AF        +    VR  
Sbjct: 196 AHAVIVGLGFVPALGVIHTGTDRSFVYDVADLYKAEVSIPAAFNAVASGTEDVGPMVRRL 255

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEIQPPA 281
            RD     + + +++  ++ V++  + +P +
Sbjct: 256 VRDAVVEQRLMPRMVRDLKFVMSVPDDEPLS 286


>UniRef50_C7MTM5 CRISPR-associated protein, Cas1 family n=6 Tax=Actinomycetales
           RepID=C7MTM5_SACVD
          Length = 342

 Score =  278 bits (712), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 112/301 (37%), Positives = 169/301 (56%), Gaps = 7/301 (2%)

Query: 4   LPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
            P +   L DRVS ++++   +D  + A  +I++      +P   VA ++L PGTRV+H 
Sbjct: 11  HPHDLHRLTDRVSSVYIERSHLDRAENAIAIINRRET-VRLPAALVAVVLLGPGTRVTHG 69

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
           A++L A  GT + WVGE GVR+YA+G      +  L  QA L      RL+V R M+ +R
Sbjct: 70  AMQLLADSGTAVCWVGEQGVRMYAAGLGPSRGAALLQRQAYLVSRTTTRLEVARAMYAMR 129

Query: 124 FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD-WEKGDTINQCISA 182
           F     +  +++QLRG EG+RVR  Y   A+Q+GV WNGR Y   D +  GD +N+ +SA
Sbjct: 130 FPGEDVSTLTMQQLRGREGARVRKVYRQQARQHGVPWNGRAYKAGDAFAVGDDLNRLLSA 189

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           A + LYG+  A I+  G +P +GF+HTG   SFV DIAD+ K +  +P AF++A R   E
Sbjct: 190 ANAALYGICHAVIVGLGASPGLGFIHTGSATSFVMDIADLYKAEYTIPLAFQLAARGLLE 249

Query: 243 PDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVSLG 298
            +R+ R A RD    +  L ++I  ++ +LA   +  P P      D +   +P  V+  
Sbjct: 250 -ERDARTALRDRIAGTGLLPRIIKDVKTLLAPEGVDLPDPEVNLLWDERGNPVPGGVNWS 308

Query: 299 D 299
           D
Sbjct: 309 D 309


>UniRef50_Q3ZZ81 CRISPR-associated protein Cas1 n=4 Tax=Bacteria RepID=Q3ZZ81_DEHSC
          Length = 309

 Score =  277 bits (709), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 116/283 (40%), Positives = 174/283 (61%), Gaps = 1/283 (0%)

Query: 6   LNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAV 65
                 +DR S ++L+ G++DV   +            +P+  +  +ML PG+ V+HAA+
Sbjct: 5   HELPRFRDRWSYLYLEMGRLDVEADSLGFHQGD-TVVPVPIDQLGVVMLGPGSTVTHAAI 63

Query: 66  RLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG 125
           +  +Q   L+ W G+ GVR+YA+   G   + +L+ QA+L  D++ RL+V  +M+  RF 
Sbjct: 64  KSLSQNNCLIAWTGQDGVRLYAASIGGTYSARRLIRQARLVSDDEKRLEVAWRMYRFRFN 123

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
           E  P   S+E +RG+EG RVR  YA  +++YGV W GR YD KDW KGD IN+ +SAA +
Sbjct: 124 EVIPPVVSLESIRGMEGIRVRRAYAKASQEYGVEWKGRHYDQKDWSKGDPINRALSAANA 183

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDR 245
           CLYG+  A IL+AGY+ A+GFVHTGK LSFVYD+AD+ K +  +P AF++A  NP + +R
Sbjct: 184 CLYGICHAGILSAGYSSALGFVHTGKMLSFVYDVADLYKTELTIPVAFKVAAANPTDLER 243

Query: 246 EVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQP 288
           +VR+ CR+ F   K L +L+  I +VL   +    +P E    
Sbjct: 244 QVRIECREAFYEFKLLERLLTDIAEVLGVSDDIGESPDEFEGR 286


>UniRef50_A8M406 CRISPR-associated protein Cas1 n=5 Tax=Actinomycetales
           RepID=A8M406_SALAI
          Length = 322

 Score =  274 bits (700), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 114/293 (38%), Positives = 160/293 (54%), Gaps = 5/293 (1%)

Query: 10  PLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
             +DR+S ++L+   I     A    D+ G   HIP  ++  +ML PGT ++  A+ L A
Sbjct: 16  RAQDRISFVYLERCVIHRDSNAITATDEKG-IVHIPAATLGVLMLGPGTSITQQAMMLIA 74

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP 129
             G  +VW+GE GVR YA G+P    S  L+ QA      D RL+V R M+ +RF     
Sbjct: 75  DNGATVVWIGEHGVRYYAHGRPLARSSRLLVAQAAAVSHRDRRLRVARAMYRMRFPGEDT 134

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
              +++QLRG EG+RVR  Y   A++ GV+WN R YDP D+   D +NQ +SAA +CLYG
Sbjct: 135 TNLTMQQLRGKEGARVRRCYRENAQRTGVSWNSREYDPDDFTGSDPVNQALSAAHACLYG 194

Query: 190 VTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRL 249
           +  A ++A G +P +GFVHTG   SFVYDIAD+ K D  +P AF+IA     +   + R 
Sbjct: 195 IVHAVVVAVGASPGLGFVHTGHDRSFVYDIADLYKADVTIPVAFDIAAAESTDIGADTRR 254

Query: 250 ACRDIFRSSKTLAKLIPLIEDVL----AAGEIQPPAPPEDAQPVAIPLPVSLG 298
           A RD   +   L + +  I  +L    AAG I      E+A   A+ L    G
Sbjct: 255 AVRDRVHNGALLGRCVQDIRRLLLTDSAAGPINEEEFDEEADNDAVRLWDEGG 307


>UniRef50_C7MTL6 CRISPR-associated protein, Cas1 family n=4 Tax=Actinomycetales
           RepID=C7MTL6_SACVD
          Length = 328

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 96/319 (30%), Positives = 161/319 (50%), Gaps = 26/319 (8%)

Query: 4   LPLNPI---------PLKDRVSMIFLQYGQIDVIDGAF--VLIDKTGIRTHI--PVGSVA 50
            P   +          + D +S ++L+  ++   D      +    G  + +  PV +++
Sbjct: 7   HPRRLLTAPTVAMLPRVADSLSFLYLENVRVVQDDTGVCAYVEQPDGGTSRVYLPVAAIS 66

Query: 51  CIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDED 110
           CI+   GT V+  A+   A+  T ++W G  GVR+Y+        ++ L  Q +   D+ 
Sbjct: 67  CILFGTGTSVTQPAMATCARHNTTVLWTGSGGVRMYSGSLAPNLTTEWLERQVRAWADDS 126

Query: 111 LRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDW 170
            RL V  +M+ +RFG   PA  S+  LRG+EG R++A Y  LA ++G+    R YDP +W
Sbjct: 127 TRLAVAARMYSMRFGAEVPAGTSLNTLRGLEGQRMKALYRSLADRHGLRGFKRNYDPANW 186

Query: 171 EKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVP 230
            + + +NQ +SAA + LYG   +A+LA G +PA+GF+H+GK  SFVYD+AD+ K    +P
Sbjct: 187 GEQNPVNQALSAANTALYGAVHSALLALGCSPALGFIHSGKQHSFVYDVADLYKAKHTIP 246

Query: 231 KAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA---AGEIQPPAPP---- 283
            AF + +     PDREVR+  R  F   + + +++  ++ +L    A +      P    
Sbjct: 247 LAFALHKSAQ--PDREVRIRMRQDFHLYRLMPRIVRDVQRLLDPSIAQDHDETGEPEEVE 304

Query: 284 ----EDAQPVAIPLPVSLG 298
                D    A+   V+ G
Sbjct: 305 LVHLWDPDLGAVEAGVNHG 323


>UniRef50_C2BS02 CRISPR-associated protein n=1 Tax=Mobiluncus curtisii ATCC 43063
           RepID=C2BS02_9ACTO
          Length = 314

 Score =  264 bits (675), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 90/296 (30%), Positives = 152/296 (51%), Gaps = 6/296 (2%)

Query: 8   PIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRL 67
              ++DR+S ++++   ++    A  + D  G   HIP   V  ++L PGT+V++AA+ L
Sbjct: 15  LSRMEDRLSFLYVERAILNREGNALTIQDSRG-IAHIPATQVGVVLLGPGTKVTYAAMAL 73

Query: 68  AAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP 127
               G   VWVGE GVR YA G+P    S      A+L  ++  RL+  R+M+ +RF   
Sbjct: 74  LGDAGCSAVWVGEKGVRYYAHGRPAAKTSRMAEAHARLWANQRSRLRCARRMYSMRFPGE 133

Query: 128 APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCL 187
             +   + QLRG EG+R++  YA  +++ GV W  R YDP D+  GD IN  ++   + L
Sbjct: 134 DVSNLPLSQLRGREGARMKRIYAEQSRRTGVPWTRRSYDPNDFGAGDPINCALTEGAAAL 193

Query: 188 YGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREV 247
           YG+  A ++  G+ P++G +H+G   +FVYD+AD+ K +  +P AFE    +    +  V
Sbjct: 194 YGIAHAVVVGLGFIPSLGIIHSGTDRAFVYDVADLYKAEISIPAAFEAVAASAEGDELNV 253

Query: 248 RLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP----EDAQPVAIPLPVSLGD 299
           R   RD   +++ + +++  ++ V+                D     I   V+  D
Sbjct: 254 RKRIRDKVVTTRLMQRMVRDLQYVMEIPTDDAYIDANLLLWDELE-VIAAGVNWAD 308


>UniRef50_Q03C58 CRISPR-associated protein n=3 Tax=Lactobacillus RepID=Q03C58_LACC3
          Length = 315

 Score =  261 bits (667), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 106/298 (35%), Positives = 169/298 (56%), Gaps = 6/298 (2%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVR 66
               +++RV+ ++L++ +I+  D A V+ID  G    IP   ++ +ML PG  V+H A+ 
Sbjct: 12  ELSRVRERVTFLYLEHAKINRQDSAIVVIDTGGT-VAIPAALISVLMLGPGVDVTHRAME 70

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
           L    G  +VWVGE GVR YA G+     S  L+ QAKL  +  LR+ V R+M+++RF +
Sbjct: 71  LMGDAGMSVVWVGERGVRQYAPGRALTHSSALLVAQAKLVSNNRLRVGVARQMYQMRFPD 130

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
              +  S+++LRG EG+RVR  Y   +++ GV W  R YDP++++ G  INQ ++AA + 
Sbjct: 131 DDVSTLSMQELRGKEGARVRRIYREESRRTGVEWTHREYDPENYQSGSIINQALTAAHAA 190

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR--NPGEPD 244
           LYG++ + I+A G +P +GFVHTG  LSFVYD AD+ K +  +P AF +A       +  
Sbjct: 191 LYGLSYSVIVALGASPGLGFVHTGHDLSFVYDFADLYKAEVTIPIAFTVAANATEQDDIG 250

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP---EDAQPVAIPLPVSLGD 299
           +  RLA RD F   K + +++  ++ +L   +    A      D +       VS  +
Sbjct: 251 QLTRLAVRDAFVDGKLMIRMVADLKMLLGDVDDDLDADVVNLWDDKLGLQKFGVSYRE 308


>UniRef50_Q47PJ6 CRISPR-associated protein, Cas1 family n=4 Tax=Actinomycetales
           RepID=Q47PJ6_THEFY
          Length = 332

 Score =  244 bits (622), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 90/312 (28%), Positives = 156/312 (50%), Gaps = 21/312 (6%)

Query: 8   PIPLKDRVSMIFLQYGQIDVIDGAF--VLIDKTGIRTHIPV--GSVACIMLEPGTRVSHA 63
              + D +S +++   +I   D      +  +TG    +P+   S+AC++L PGT ++  
Sbjct: 16  LPRVSDGLSFLYVDVCRIVQTDTGVCAEVETETGRIHRVPIPTASLACVLLGPGTSITSP 75

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
           A+    +  T +V  G  G+  Y S       +  +  QA+   D+  R  V  +M+E+R
Sbjct: 76  AMATFMRHNTTVVTCGAGGILNYGSFPAPNRTTKWIDRQARAYSDDRRRRDVAVRMYEMR 135

Query: 124 FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
           FGE  P   S+E+LR +EG+R++A Y  LA +  V    R Y+P DW+  D +N+ +SA+
Sbjct: 136 FGEEPPPGASIERLRQLEGARMKALYRSLAAKNRVKPFKRNYNPHDWDDQDPVNKALSAS 195

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            + LYGV  + +   G  PA+GF+H+GK  +FVYDIAD+ K  T +P AF ++R     P
Sbjct: 196 NAALYGVVHSVLAHLGCHPALGFIHSGKQDAFVYDIADLYKARTTIPLAFSLSRT--ANP 253

Query: 244 DREVRLACRDIFRSSKTLAKLIPLIEDVLA----AGEIQPPAPP-----------EDAQP 288
           ++E RL  R   +  + + +++  ++ +L+       +    PP            D   
Sbjct: 254 EQEARLRLRRDLKLYRLIPQIVRDVQTLLSLDDPEEAVSEEEPPSSGGPWQVVDLWDPVV 313

Query: 289 VAIPLPVSLGDA 300
            A+   V+  + 
Sbjct: 314 GAVSGGVNYANH 325


>UniRef50_C4X9I5 CRISPR-associated Cas1 family protein n=12 Tax=Bacteria
           RepID=C4X9I5_KLEPN
          Length = 294

 Score =  242 bits (619), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 92/274 (33%), Positives = 147/274 (53%), Gaps = 2/274 (0%)

Query: 6   LNPIP-LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
              +P +KD+   ++L+ G++++ D +   +D  G    +PV ++  ++L PGT V+H A
Sbjct: 16  RELLPQVKDKYPFLYLERGRLEIDDSSVKWVDADGNVVPLPVATINTLLLGPGTTVTHEA 75

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           ++ A      + WVGE  +  YA+G    A +  L  Q  LA D    LKV R MF  RF
Sbjct: 76  IKTATAANCAVCWVGEDSLLFYAAGFLPTADTRNLKAQMALACDASSTLKVARAMFAKRF 135

Query: 125 GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +     +S+  + G+EGSRVRA Y   A++YGV W GR++ P  +E  D  NQ +++  
Sbjct: 136 PDADLEGKSLNSMMGMEGSRVRALYQQKAQEYGVGWKGRQFTPGKFELSDLTNQVLTSTN 195

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           + LYG+  + + A GY+P IGF+H+G PL FVYD+AD+ K    +  AF ++R   G  D
Sbjct: 196 AALYGILCSVVHAMGYSPHIGFIHSGSPLPFVYDLADLYKERLCIDLAFSLSREMAGRYD 255

Query: 245 RE-VRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           +  V  A R    +   L  +   I +++     
Sbjct: 256 KHKVSEAFRKRVIALDLLNLIAADINELMGGKGA 289


>UniRef50_B6IWM1 CRISPR-associated protein Cas1, putative n=1 Tax=Rhodospirillum
           centenum SW RepID=B6IWM1_RHOCS
          Length = 281

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 86/275 (31%), Positives = 136/275 (49%), Gaps = 6/275 (2%)

Query: 4   LPLNPIPLKDRVSMIFLQYGQIDVIDGAFVL-IDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           L    IP K R  +I+++  ++ + +G+ V+  D  G    +P   +  ++L PG+ ++H
Sbjct: 8   LDAARIPQKSRNGLIYVERCRLSIDNGSLVIAFDDRGEELELPYQRLNAVLLGPGSSITH 67

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
            AVR  +  GT L +VG  G R+Y +       S     QA     E  R+ V ++M+  
Sbjct: 68  DAVRHCSGHGTCLAFVGSDGTRLYTAPPLFDRDSTLARQQATWWAGESTRIMVAKRMYAK 127

Query: 123 RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISA 182
           RFGE  P   S++ LRG+E +R+R +Y L+A Q G+ W GRR+D  D +  D  NQ I+ 
Sbjct: 128 RFGE-TPRATSLDSLRGMEAARIRHSYELIAAQAGIVWRGRRFDRSDPDGDDLPNQAINH 186

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR---- 238
             + +      A+ A G  P +GF+H     S+  DI D+ +    VP AF   +R    
Sbjct: 187 VVTAVEACVAIAVQATGTLPPLGFLHEDSAKSWTLDICDLYRTSVTVPLAFRCVKRIDQG 246

Query: 239 NPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
                DR  R A     R +  +  +I  I++VLA
Sbjct: 247 ATDSLDRICRRAVSAHVRDTGFIDTIIDDIKEVLA 281


>UniRef50_C9M9R9 CRISPR-associated protein Cas1 n=1 Tax=Jonquetella anthropi E3_33
           E1 RepID=C9M9R9_9BACT
          Length = 281

 Score =  233 bits (595), Expect = 5e-60,   Method: Composition-based stats.
 Identities = 97/279 (34%), Positives = 146/279 (52%), Gaps = 10/279 (3%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGI-----RTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           M++L+ G + V DG    +   G         IP  +V+ I+LEPGT ++H   RL  Q 
Sbjct: 1   MLWLERGNLFVKDGTLRFVSAGGGSLEKGTYDIPYQNVSMIVLEPGTTITHDVFRLMGQQ 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPAR 131
           GT L+ VG+ GVR Y +   G  RS     Q +L  +   RL+V   M+ +RFGE  P R
Sbjct: 61  GTGLIAVGDKGVRCYTAPPLGPDRSALARRQVELWANPQTRLQVALAMYAIRFGEELPTR 120

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVT 191
           + +E LRGIEG+R+R +Y++LAK YG+TW  RR++ K   K D IN  ++ A S +YG  
Sbjct: 121 K-IEDLRGIEGARLRKSYSILAKFYGLTWTLRRFNRKQPNKTDDINAAVNHAASAMYGAA 179

Query: 192 EAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP----DREV 247
           + A+ A    P +GFVH     +F  DIAD+ + +  +P AF        EP    +R V
Sbjct: 180 DIAVAAVSAIPQLGFVHAKSCRAFALDIADLYRTEITLPAAFRGLASYLEEPGMDLERHV 239

Query: 248 RLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDA 286
           R          K ++K+I  I++++  G+       +  
Sbjct: 240 RKLIGQELYRQKVISKMIDQIKELILHGQSDEALEEKSP 278


>UniRef50_Q21QB1 CRISPR-associated protein Cas1 n=1 Tax=Rhodoferax ferrireducens
           T118 RepID=Q21QB1_RHOFD
          Length = 277

 Score =  225 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 104/267 (38%), Positives = 152/267 (56%), Gaps = 9/267 (3%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
            K+R+  +FL+ G + V DG  +L+ +      IP   V+C+M+EPG  V+H A++L  +
Sbjct: 17  HKNRIPYLFLEKGILRV-DGHCLLLCQAESAIEIPGSMVSCLMIEPGVSVTHEAMKLCGE 75

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
            GTLL+WVGE G R YA+       + ++L QA +  ++  R+    +++ L F +  P 
Sbjct: 76  NGTLLMWVGEGGTRFYAAAHA-HQDASRVLRQAAIHTNQRERIAAASRLYGLMFDDHMPP 134

Query: 131 RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
             ++E+LRG+EGSRV+  Y  LA + G+ W GR            +N  I  ATSCLY +
Sbjct: 135 SFTIEKLRGLEGSRVKEIYVNLADKLGMVWQGREEKS-------ALNTSIGFATSCLYAL 187

Query: 191 TEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
            E AILAAGY P IG VH+G P S V+D+AD +KF TVVP AFEIA  +P   +  VR  
Sbjct: 188 CEVAILAAGYHPGIGVVHSGNPRSLVFDLADTVKFKTVVPLAFEIAATSPSNLNMAVRHG 247

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           CRD+F        L+  +E++      
Sbjct: 248 CRDLFSRESMFETLLGHLENIFGTDHD 274


>UniRef50_C8W2P4 CRISPR-associated protein Cas1 n=1 Tax=Desulfotomaculum acetoxidans
           DSM 771 RepID=C8W2P4_DESAS
          Length = 545

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 48/308 (15%), Positives = 90/308 (29%), Gaps = 34/308 (11%)

Query: 5   PLNPIPLKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           P  P+P  +   ++++      +        +     +   IP+ ++  ++L     +S 
Sbjct: 203 PARPLPSLNLGRVLYVDEPGAYVRKKGERVQVTRDKEVLVDIPLCNLEQLVLAGTVNISA 262

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
             ++L    GT + +V  AG    +        S   + Q K   D +LRLK      + 
Sbjct: 263 QVIKLLLDRGTEVHFVSRAGKYYGSLQPALTKNSALRIAQHKAYQDMELRLKYAVLFVQG 322

Query: 123 RFGEPAP-----------------------------ARRSVEQLRGIEGSRVRATYALLA 153
           +                                      S+  L GIEG+  R  + +  
Sbjct: 323 KLANMRTILLRYNRDLKEKQLEEAICRLKSLSKNLYKADSLNSLMGIEGAATREYFRVFN 382

Query: 154 KQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK-- 211
                              GD +N  +S A + L     A++   GY P IGF+H     
Sbjct: 383 YMIKQHVPFNFQQRSRRPPGDPVNALLSFAYTLLTKDMIASVSIVGYDPYIGFLHRSDYG 442

Query: 212 PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDV 271
             +   D  +  +          +  +     D +        F +     K     E+ 
Sbjct: 443 RPALALDFIEEFRPIVADSVVLTVLNKGMINTD-DFEYKMGGCFLNDSGRKKFYRAYEER 501

Query: 272 LAAGEIQP 279
                  P
Sbjct: 502 RHEMISHP 509


>UniRef50_Q0AA34 CRISPR-associated protein Cas1 n=11 Tax=Bacteria RepID=Q0AA34_ALHEH
          Length = 298

 Score =  222 bits (567), Expect = 9e-57,   Method: Composition-based stats.
 Identities = 90/279 (32%), Positives = 142/279 (50%), Gaps = 10/279 (3%)

Query: 9   IPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIR-----THIPVGSVACIMLEPGTRVSHA 63
           IP  DR  +++L  G++ V DG                  IP   ++ I+L PG+ V+H 
Sbjct: 18  IPHVDRHGLLWLTRGRLYVEDGTLHFTAAESEDLAAGDYAIPYQGLSMILLGPGSTVTHD 77

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
            +RL A+ GTLL  +G  G + Y +   G  RSD     A L  ++  RL V R+M+  R
Sbjct: 78  VLRLLARHGTLLAAIGGGGTKYYTAPPMGQGRSDVARRHATLWANKTQRLDVARRMYAFR 137

Query: 124 FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
           FG   P  + +  LRGIEG R++  Y + A ++G+ W GRRY+  +    D  NQ I+ A
Sbjct: 138 FGRVLPH-KDIAVLRGIEGGRIKELYRVEASRFGIPWKGRRYNRNNPSAADVPNQAINHA 196

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            + +    + A+ A G  P +GF+H     +F  DIAD+ + +  VP AF+ AR+   +P
Sbjct: 197 ATFVEAAADIAVAATGALPPLGFIHEESSNAFTLDIADLYRGEITVPLAFQAARKVLDDP 256

Query: 244 ----DREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
               +R +R      F+  K + K+I  I+D++ A +  
Sbjct: 257 TLSIERTLRRDAASAFQRHKVIPKMIDRIKDLINADDNG 295


>UniRef50_C1ZJF3 CRISPR-associated protein, Cas1 family; CRISPR-associated
           exonuclease, Cas4 family n=1 Tax=Planctomyces
           limnophilus DSM 3776 RepID=C1ZJF3_PLALI
          Length = 598

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 50/307 (16%), Positives = 90/307 (29%), Gaps = 38/307 (12%)

Query: 6   LNPIPLKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
              +P +D    I++Q     I        L         IP+  V+ + L    +V+ A
Sbjct: 261 RKLVPARDDALPIYVQDQGTYIGKDGERLKLTPAKSSPLFIPLIQVSQVCLMGNVQVTAA 320

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
           A+R  A     + +    G     +        +  + Q+K A D    L + R     +
Sbjct: 321 AIRELADRNIPISYFSYGGWFTALTSGMCHKNVELRMAQSKAAFDPQAALSIARGFISAK 380

Query: 124 FG-------------------------EPAPARRSVEQLRGIEGSRVRATYALLAKQYG- 157
                                      +      ++  L G+EG   +  +A  ++    
Sbjct: 381 IKNSRTLLRRHADDKHRSDLDRLADYIQKVEQVDNLNSLMGLEGMAAKTYFAGFSRLLRG 440

Query: 158 ---VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--P 212
                  GR   P      D +N  +S   S L         A G+ P +GF+H  +   
Sbjct: 441 GDEFNLEGRNRRPP----TDPVNALLSFVYSLLTKELTITTQAVGFDPFLGFLHQPRYGR 496

Query: 213 LSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
            S   D+A+  +          +       P   +R A       +     +I   E  +
Sbjct: 497 PSLALDLAEEFRPLVGDSTVLTLINNEEVSPKSFIRRAGSVALTET-GRKAVIAAYERRM 555

Query: 273 AAGEIQP 279
                 P
Sbjct: 556 ETEITHP 562


>UniRef50_D0MKV7 CRISPR-associated protein Cas1 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MKV7_RHOM4
          Length = 553

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 38/303 (12%), Positives = 91/303 (30%), Gaps = 30/303 (9%)

Query: 6   LNPIPLKDRVSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
              +P ++    +++  Q   +       ++  +     H  +  ++ + +    +++  
Sbjct: 216 RRLVPSRNDRLPLYVLSQGSVVKRKGAQLLVQTQDDKDQHFRLIDLSRVSIFGNVQITTQ 275

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE-- 121
           A+R   +    + +   AG  +          +   + Q ++A DE   L + R +    
Sbjct: 276 AIRALVEHNIPVFFHSYAGRMLARLVSMYDVNAPVRVAQFEVAADETKSLAIARAIVTGK 335

Query: 122 -----------------------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGV 158
                                   R    A    S+++L GIEG+  R  +   ++    
Sbjct: 336 IKNQRTLLRRNQRTRSERVLRELSRLAREARRASSLDELLGIEGAAARLYFRQFSRMLRH 395

Query: 159 TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFV 216
                  +       D +N  +S   + L      A++A G  P  G  H  +    S  
Sbjct: 396 RIAFDFKNRNRRPPKDPVNAMLSFLYALLLKDAMCALMATGLDPYRGIFHQMRFGRPSLA 455

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGE 276
            D+ +  +          +        + +  +           + K+I   E  +    
Sbjct: 456 LDLMEEFRPLIADSVVLRLVNTGAVT-EADFIVRGPACAMKKSAMEKVIEAYEQRMNTIL 514

Query: 277 IQP 279
             P
Sbjct: 515 RHP 517


>UniRef50_UPI00016C522C CRISPR-associated protein Cas1/Cas4 n=1 Tax=Gemmata obscuriglobus
           UQM 2246 RepID=UPI00016C522C
          Length = 571

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 49/314 (15%), Positives = 92/314 (29%), Gaps = 43/314 (13%)

Query: 6   LNPIPLKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
              IP+ D  ++++LQ     +       V+  +    T +P+ ++  +++    +VS  
Sbjct: 225 KKVIPMTDDGAVLYLQEPGTSVGKRSEHLVVKKEGQELTRVPMHAIRQVVVCGNVQVSTQ 284

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
           A+   A     + +V   G  + +              Q +   D    L + + +   +
Sbjct: 285 ALETLAANDIAVAYVTGHGRFIGSFVPAPAKNVSLREAQFRTFNDPSACLDLAKAVVRAK 344

Query: 124 FGEP-------------------------------APARRSVEQLRGIEGSRVRATYALL 152
                                                A+ SVE + GIEG      +   
Sbjct: 345 LSNQRALLMRSLRGEGEARGSHEYSAKGIYGLLGALDAQTSVESVLGIEGQGAALYFGDF 404

Query: 153 AKQYGVTWNGRRYD---PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
            +       G+ +D          D +N  +S A + L     +     G+ P  GF H 
Sbjct: 405 GRFLKQPPTGKGFDFTTRNRRPPRDPVNALLSFAYAMLAKDCFSVACTVGFDPYKGFFHV 464

Query: 210 GKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDRE--VRLACRDIFRSSKTLAKLI 265
           G+    S   D+ +  +          +       PD     R AC     + K      
Sbjct: 465 GRHGKPSLALDLMEEFRPVIADSVVLTLINNEALTPDDFIIWRDACS---LTEKGRRAFF 521

Query: 266 PLIEDVLAAGEIQP 279
              E   A     P
Sbjct: 522 AAYEQRKATVVTHP 535


>UniRef50_Q467D6 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Methanosarcina barkeri
           str. Fusaro RepID=Q467D6_METBF
          Length = 550

 Score =  218 bits (555), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 40/297 (13%), Positives = 89/297 (29%), Gaps = 30/297 (10%)

Query: 12  KDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
           KD    +++      +       V+         +P+  ++ + +     +S   +R   
Sbjct: 219 KDDKKPVYVTGWGTSVHKKGDRLVIKKNDEELQSVPLRQISQLSIYGDAHISLPVLRSLI 278

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE--- 126
           ++   + +    G     S        D  ++Q + A D +  L + RKM   +      
Sbjct: 279 EMNVPVCYFSFGGWFYGLSHGVMSKNVDLRIHQYQTAFDSERSLAISRKMIAGKIKNCRT 338

Query: 127 ----------------------PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRR 164
                                  A   + + QL GIEG+  +  ++          + + 
Sbjct: 339 LLRRNDTEVSEKILSQLNSLEKKASNAKEIGQLLGIEGTAAQIYFSRFGNMLKQDLDCKF 398

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADI 222
            +       D +N  +S     L       + + G+ P +GF H  K    +   D+ + 
Sbjct: 399 ENRNKRPPTDPVNAVLSYLYGILTKEVFVTLFSVGFDPYMGFYHQPKYGKPALALDLMEE 458

Query: 223 IKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
            +       A  +        + +  +    +     T  K+I   E  +      P
Sbjct: 459 FRPLIADSVALTLFNNKTVTLE-DFEITNFGVSLKDNTKKKIISGYERRINTEITHP 514


>UniRef50_Q74H36 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Geobacter
           sulfurreducens RepID=Q74H36_GEOSL
          Length = 559

 Score =  217 bits (554), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 48/318 (15%), Positives = 91/318 (28%), Gaps = 48/318 (15%)

Query: 5   PLNPIPLKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           P   IP   R   +++Q     +       V+ ++        +G  + + L     ++ 
Sbjct: 211 PRPIIPADGRGLPLYVQSPKAYVRKDGDCLVIEEERVRVAEARLGETSQVALFGNATLTT 270

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
           AA+    +    + W+   G  +  +   G    +   YQ + + D +  L + R+    
Sbjct: 271 AALHECLRREIPVTWLSYGGWFMGHTVSTGHRNVETRTYQYQRSFDPETCLNLARRWIVA 330

Query: 123 RFGE-------------------------------PAPARRSVEQLRGIEGSRVRATYAL 151
           +                                   A    S+E L GIEG+     +  
Sbjct: 331 KIANCRTLLRRNWRGEGDEAKAPPGLLMSLQDDMRHAMRAPSLEVLLGIEGASAGRYFQH 390

Query: 152 LAKQY--------GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPA 203
            ++          G  +  R   P      D +N  +S A + L      A+ A G  P 
Sbjct: 391 FSRMLRGGDGEGMGFDFTTRNRRPPK----DPVNALLSFAYAMLTREWTVALAAVGLDPY 446

Query: 204 IGFVHTGK--PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTL 261
            GF H  +    +   D+ +  +                      VR A      +    
Sbjct: 447 RGFYHQPRFGRPALALDMMEPFRPLIADSTVLMAINNGEIRTGDFVRSA-GGCNLTDSAR 505

Query: 262 AKLIPLIEDVLAAGEIQP 279
            + I   E  +      P
Sbjct: 506 KRFIAGFERRMEQEVTHP 523


>UniRef50_C2KP50 CRISPR-associated Cas1 family protein n=5 Tax=Actinomycetales
           RepID=C2KP50_9ACTO
          Length = 312

 Score =  216 bits (550), Expect = 9e-55,   Method: Composition-based stats.
 Identities = 71/303 (23%), Positives = 128/303 (42%), Gaps = 17/303 (5%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKT----------GIRTHIPVGSVACIMLEP 56
             I L+DRVS ++L+Y Q+         I +                IPV  +A + L P
Sbjct: 17  EQIRLEDRVSYLYLEYCQVIQNHTGVAAISEGNHDSEDREPLKRIIQIPVAGLAVLFLGP 76

Query: 57  GTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVV 116
           GT ++  A+   ++ G  +++ G  G   Y+      + S   + QA L  DE    K  
Sbjct: 77  GTSITQPAMASCSRAGLTVIFSGGGGCPYYSHAMALTSSSRWAIAQAHLVADERNARKAA 136

Query: 117 RKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
           + +++ + G       ++ Q+RG+EGS ++  Y  L++++ V    R     D    D +
Sbjct: 137 KFLYKRQLGIDIERELTISQMRGLEGSLIKKRYRELSREFKVNGFRR-----DTGGEDVL 191

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIA 236
           NQ ++     LYG   +A  A G  PA+G +H G   S ++D+AD+ K +  +P +F   
Sbjct: 192 NQALNLVNGILYGCAASACAALGVNPALGIIHRGDIRSLLFDVADLYKPNAALPISFRSV 251

Query: 237 RRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVS 296
            ++   P +  R   R        L  +I ++ +VL              +   +P    
Sbjct: 252 SKDE--PLKFARKEMRRFIYEQNVLENMISILMNVLEPYLPTIKDDRLIDESGEVPGHKD 309

Query: 297 LGD 299
             +
Sbjct: 310 YSN 312


>UniRef50_C7QUZ4 CRISPR-associated protein Cas1 n=8 Tax=Cyanobacteria
           RepID=C7QUZ4_CYAP0
          Length = 325

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 51/295 (17%), Positives = 101/295 (34%), Gaps = 35/295 (11%)

Query: 15  VSMIFLQY--GQIDVIDGAFVL----IDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +S+++L      +     AF +     D +  +  IP  +V  I+L     ++  A+  A
Sbjct: 1   MSILYLTQPDAVLSKKQEAFHVALKQEDGSWKKQLIPAQTVEQIVLIGYPSITGEALCYA 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP- 127
            ++G  + ++   G  + ++           L Q  +  +E+ RL +V+ +   +     
Sbjct: 61  LELGIPVHYLSCFGKYLGSALPGYSRNGQLRLAQYHVHDNEEQRLALVKTVVTGKIHNQY 120

Query: 128 -------------------APARRSVEQLRGIEGSRVRATYALLAKQYGVTW--NGRRYD 166
                                ++ ++EQ+RG+EG   +  +          W  NGR   
Sbjct: 121 HVLYRYQQKDNPLKEHKQLVKSKTTLEQVRGVEGLAAKDYFNGFKLILDSQWNFNGRNRR 180

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIK 224
           P      D +N  +S A   L     AA+  AG  P IG++H       + V D+ +  +
Sbjct: 181 PP----TDPVNALLSFAYGLLRVQVTAAVHIAGLDPYIGYLHETTRGQPAMVLDLMEEFR 236

Query: 225 FDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                     +      +P  +   +      S       +   E  L      P
Sbjct: 237 PLIADSLVLSVISHKEIKPT-DFNESLGAYLLSDSGRKTFLQAFERKLNTEFKHP 290


>UniRef50_C3WS02 CRISPR-associated protein n=2 Tax=Fusobacterium RepID=C3WS02_9FUSO
          Length = 335

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 39/291 (13%), Positives = 92/291 (31%), Gaps = 34/291 (11%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            I+ Q   +   +   ++    G    IP+ ++  +++  G ++S A +      G  + 
Sbjct: 5   YIYEQGIVLRYKENRLLITYTNGDYKSIPIENIDNVVIFGGIQLSTACMHNLLIKGIHVT 64

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR------------- 123
           ++ + G              D+   Q + + D+   L + +K  + +             
Sbjct: 65  FLSKTGSYFGRLESTSNINIDRQREQFRKSDDKKFCLAIGKKFIKGKATNQRTLLIRANK 124

Query: 124 ----------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDP 167
                             +     +++E+L G+EG   R  +  +       ++ +    
Sbjct: 125 DLKSEILSSVINSMFGIIKDINDSKTIEELMGVEGYLARLYFNAINHIIDKKYSFKT--R 182

Query: 168 KDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKF 225
                 D  N  IS   + L+      ++  G  P   F+H+ +    +   D+ +  + 
Sbjct: 183 TKRPPKDPFNAVISFGYTLLHYEIFTTLVTKGLNPYAAFLHSDRHKHPALCSDLMEEWRA 242

Query: 226 DTVVPKAFEIARRNPGEPDRE-VRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
             V   A  +   N    +          +F + K   K +   E  L   
Sbjct: 243 ILVDSMAIALLNNNKIAYEDFNFDEKSGGVFLNKKACGKFVEQFEKRLRQE 293


>UniRef50_B9K7F7 CRISPR-associated protein, Cas1 family n=1 Tax=Thermotoga
           neapolitana DSM 4359 RepID=B9K7F7_THENN
          Length = 329

 Score =  214 bits (545), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 51/309 (16%), Positives = 98/309 (31%), Gaps = 35/309 (11%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKT---GIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +      G++   +   ++  +      R  IPV ++  I       ++   +  AA+  
Sbjct: 7   NYYVFSSGRVKRHENTILIEYQKAGMQQRKFIPVENIDQIFFLGEVDLNSKFLDFAAKNN 66

Query: 73  TLLVWVGEAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVRKMFE---LRFGE 126
            +L +    G   Y             + L+ Q +  LD + RL + RK  E     F  
Sbjct: 67  IVLHFFNYYG--YYTGSFYPREKFISGELLVRQVEHYLDSEKRLTLARKFVEGAVHNFKR 124

Query: 127 PAPA------------------RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPK 168
                                  +++ +L   E    +  Y+   +  G  +  R   P 
Sbjct: 125 NIEKRGFDITDKISEYLERTKYAKTIPELMSCEAHARKLYYSTWEEITGWPFEERSMQPP 184

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFD 226
                + +N  IS   S  Y +    +      P I ++H    K  S   DIA+I K  
Sbjct: 185 ----LNELNALISFGNSLTYSIVLKELYFTHLNPTISYLHEPGTKRFSLALDIAEIFKPI 240

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDA 286
            V    F++      + ++      R +F + +     I   E++L    +      +  
Sbjct: 241 FVDRIIFKLINLKKIDREKHFLQEARGVFLNEEGRRLFIEEFENMLQQTILHRKLKRKIK 300

Query: 287 QPVAIPLPV 295
               I L  
Sbjct: 301 YQSLIRLEA 309


>UniRef50_B7KMR5 CRISPR-associated protein Cas1 n=3 Tax=Chroococcales
           RepID=B7KMR5_CYAP7
          Length = 558

 Score =  214 bits (544), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 61/318 (19%), Positives = 107/318 (33%), Gaps = 46/318 (14%)

Query: 3   WLPLNPIPLKDRVSMIFL-QYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRV 60
           W P+   P+ D   +I + + G ++        +         I +G V+ ++L   +++
Sbjct: 210 WHPVRLFPVDDEREVIHVLEPGTRVGRTGEQLKISRPNQPDEKIAIGQVSQVVLHSFSQI 269

Query: 61  SHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF 120
           S  AV   A     + +V   G R   S         + + Q +     D  L++ RK+ 
Sbjct: 270 STQAVHFLAYKEVGIHFVSGGG-RYIGSIDARSRSIQRRVRQYQALSQPDFCLELARKLV 328

Query: 121 ELRFGEP-------------------------------APARRSVEQLRGIEGSRVRATY 149
             R                                    P  +S++ L GIEG+     +
Sbjct: 329 ACRGEGQRKFLMRGKRNKKGDSLALEKTIAQMKAVLKQVPQIQSLDSLLGIEGNLAALYF 388

Query: 150 ALLAKQY------GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPA 203
             L+          + ++GR   P      D  N  +S   S L      AILA G  PA
Sbjct: 389 GALSNLLAENAPESLLFSGRNRRPPK----DRFNALLSFGYSLLIKDVMNAILAVGLEPA 444

Query: 204 IGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTL 261
           +GF H  +  +     D+ +I +   V         R+  +   +  +  + ++ S    
Sbjct: 445 LGFYHQPRTQAPPLALDLMEIFRVPLVDMPVVTSINRSQWDIQADFDVRGQQVWLSDSGR 504

Query: 262 AKLIPLIEDVLAAGEIQP 279
            K I L E   A     P
Sbjct: 505 RKFINLYEQRKAETWKHP 522


>UniRef50_B8GLF6 CRISPR-associated Cas1/Cas4 family protein n=1 Tax=Thioalkalivibrio
           sp. HL-EbGR7 RepID=B8GLF6_THISH
          Length = 570

 Score =  210 bits (535), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 39/315 (12%), Positives = 91/315 (28%), Gaps = 45/315 (14%)

Query: 5   PLNPIPLKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           P      +D    +++Q    ++        +         + +  V+ +++     ++ 
Sbjct: 225 PRPLAVARDEALPLYIQARGAKLAKRGETLEVTVDDEKVQSVRLIDVSQVIVMGNVYITT 284

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
             ++   Q    + W    G  +  +   G    +    Q K + +E   L + + + E 
Sbjct: 285 PCLQELMQREIPVSWHSHGGWFMGHTMGTGHKNVEIRTAQYKASFEEHQCLHIAKGLVEA 344

Query: 123 RFGE---------------------------PAPARRSVEQLRGIEGSRVRATYALLAKQ 155
           +                               +    ++++L GIEG+     +   A+ 
Sbjct: 345 KIQNCRTLLRRNWKGEDKPVDLLDGLQVDIRKSRRASNLQELLGIEGAAASRYFGAFARL 404

Query: 156 YG---------VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGF 206
                        +  R   P      D +N  +S A + L     A++ A G  P  GF
Sbjct: 405 LKHSDAGPELTFDFTTRNRRPP----TDPVNALLSYAYALLTRSWTASLSAVGLDPYRGF 460

Query: 207 VHTGK--PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKL 264
            H  +    +   D+ +  +         +        P     +A      +     + 
Sbjct: 461 YHQPRYGRPALALDMMEPFRPLIADSSVIQAINNGEVRPSDFQSVAGSVALTND-GRKRF 519

Query: 265 IPLIEDVLAAGEIQP 279
           I   E  ++     P
Sbjct: 520 IATFERRMSHEITHP 534


>UniRef50_A5ILM3 CRISPR-associated protein, Cas1 family n=3 Tax=Bacteria
           RepID=A5ILM3_THEP1
          Length = 327

 Score =  210 bits (535), Expect = 5e-53,   Method: Composition-based stats.
 Identities = 46/291 (15%), Positives = 93/291 (31%), Gaps = 32/291 (10%)

Query: 16  SMIFLQYGQIDVIDGAFVLI----DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +      G+I   + + ++     D    +  IPV +V  I       ++   +  AA+ 
Sbjct: 4   NYYVFSSGRIRRRENSILIEYQDRDGKQQKRFIPVENVDQIFFLGEVDLNSKFLDFAAKN 63

Query: 72  GTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE--------- 121
             +L +    G    +   +      + L+ Q +  LD + RL + RK  E         
Sbjct: 64  NIVLHFFNYYGYYTGSFYPREKFLSGELLVRQVEHYLDNEKRLSLARKFVEGAIHNFKRN 123

Query: 122 ------------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD 169
                         + E      ++ +L   E    +  Y+         +  R   P  
Sbjct: 124 IEKRGFDIVSKISEYQERIKHVATIPELMSCEAHARKLYYSTWEDITDWPFEERSMQPP- 182

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDT 227
               + +N  IS   S  Y V    +      P + ++H    K  S   DI++I K   
Sbjct: 183 ---LNELNALISFGNSLTYSVVLKELYHTHLNPTVSYLHEPGTKRFSLALDISEIFKPIF 239

Query: 228 VVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           V    F++      + +         +F + +     +   E++L    + 
Sbjct: 240 VDRIIFKLINLGKIKRENHFLQESNGVFLNDEGRRIFVEEFENMLQQTVLH 290


>UniRef50_UPI0001C16754 protein of unknown function DUF48 n=1 Tax=Cylindrospermopsis
           raciborskii CS-505 RepID=UPI0001C16754
          Length = 334

 Score =  208 bits (530), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 45/288 (15%), Positives = 93/288 (32%), Gaps = 35/288 (12%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            +  Q   +  ID    +       T +P+  +  +++     ++  A+++  Q    + 
Sbjct: 5   FLLEQDTLVRQIDERLEIFKHDKRLTDVPLCKLESVVVYGRVILTIPALKILNQRSIPIT 64

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------LRFGE 126
           ++ E G  V          +     Q + + D    L + R++             RF  
Sbjct: 65  YLSEEGRTVATLLPEPNPNAILRSKQYQASFDTHKTLAIAREIIRGKLFNQHTILARFSR 124

Query: 127 PAPAR--------------------RSVEQLRGIEGSRVRATYALLAKQY-GVTWNGRRY 165
                                     S+ +LRG EG    + + +L +   G  W+    
Sbjct: 125 QNERSEKVISALKSLKACQKSIDQTTSLNELRGYEGQGASSYFGVLGELLTGTPWSF--S 182

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADII 223
                   D +N  +    + LYG   AA+   G  P  GF+H  +    +   D+ +  
Sbjct: 183 HRTRRPPTDPVNALLGFGYALLYGDCRAALHTVGLDPYQGFLHGERYGRANLALDLMEEF 242

Query: 224 KFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDV 271
           +   V     ++ R N  E +  +      +  + + + K I   E  
Sbjct: 243 RPIFVDGLVLQLLRNNSLEKESFINYPGGAVHLNEQGMKKFIQSYEQR 290


>UniRef50_C9M4E6 CRISPR-associated protein cas1 n=1 Tax=Lactobacillus helveticus DSM
           20075 RepID=C9M4E6_LACHE
          Length = 332

 Score =  207 bits (528), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 48/293 (16%), Positives = 91/293 (31%), Gaps = 41/293 (13%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
                 G+++  D    L    G    + +     I L      +   +   AQ+   + 
Sbjct: 7   YYLFSSGELERKDNTVRLTRSDGKYKDLKIEVTRDIYLFGEVSTNTKCLNYLAQMKIPVH 66

Query: 77  WVGEAGVRVYASGQPG---GARSDKLLYQAKLALDEDLRLKVVRKM-------------- 119
           +    G   Y               L+ Q +   D   RL   +K               
Sbjct: 67  FFNYYG--FYTGSFYPKEQNVSGTLLIQQVQAYTDPKRRLYYAKKFVLGAAKNLLRNLKY 124

Query: 120 FELRFGEPAPARR-------------SVEQLRGIEGSRVRATYALLAKQY--GVTWNGRR 164
           ++ R      + +              VE+L G+EG+  R  YA     +   V ++ R 
Sbjct: 125 YQRRGRNLDDSIKEITSLIRQIDQVHDVEELMGVEGTIHRRYYASWQSVFIPDVDFSKRV 184

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADI 222
             P D    + +N  IS     +Y    + I      P I ++H+   +  S   DI++I
Sbjct: 185 RRPPD----NMVNTLISFLNGLMYTTCLSEIYVTQLNPTISYLHSPMDRRFSLCLDISEI 240

Query: 223 IKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
            K   V    F +  +N    + +        + S K+   ++   +  +   
Sbjct: 241 FKPMIVDRLIFSLINKNMIS-EEDFNKESNYCYLSEKSKRIIVSEYDKYMKQK 292


>UniRef50_C4G3M4 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G3M4_ABIDE
          Length = 340

 Score =  207 bits (528), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 51/306 (16%), Positives = 105/306 (34%), Gaps = 39/306 (12%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +++  Q  +I  I G F+L  K G    +P   +  I +   + ++  A++   +  
Sbjct: 7   MSCLYVVEQGSKIKHIGGQFILEVKDGENRVVPDEILESISIFGNSVLTTQAIKACLEKN 66

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP----- 127
             + ++   G              D+L  QA L+ + D  LK  + + + +         
Sbjct: 67  INVSFLSTKGRYFGKLMSNTATNPDRLKAQAYLSDNIDECLKFAKIILKAKINNQDVILR 126

Query: 128 -----------------------APARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNG 162
                                      + + ++ G EG   R  +  L+K       ++G
Sbjct: 127 RYAKSSEADISSHIKDLKIYEEHIEKGKDINKIMGYEGIAARTYFEALSKLIKPEFKFSG 186

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIA 220
           R   P      D  N  +S   S +Y    + I     +P IGF+H    +  + V D+ 
Sbjct: 187 RNKRPPK----DAFNSMLSLGYSLIYNEIFSEIENRNLSPYIGFIHKLKDRHPALVSDLI 242

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDI-FRSSKTLAKLIPLIEDVLAAGEIQP 279
           +  +   V      + + N    +   +    +  F S   + +++  IE+ L +     
Sbjct: 243 EEWRAVLVDATMMSLIQGNEILIEEFTKDEYSEAVFISDLAVKQIVRKIENKLRSQNNYL 302

Query: 280 PAPPED 285
               E 
Sbjct: 303 EYLNEP 308


>UniRef50_C1DUM1 Crispr-associated protein Cas1 n=18 Tax=Bacteria RepID=C1DUM1_SULAA
          Length = 331

 Score =  207 bits (526), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 46/295 (15%), Positives = 88/295 (29%), Gaps = 36/295 (12%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGI---RTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +      G+I   +       +      +T +P+  +  I +     ++  A+   +Q  
Sbjct: 4   NYYINSNGRIRRKENTVYFETEKDGESLKTPLPINDIDTIFIFGEVDINTKAINYLSQYD 63

Query: 73  TLLVWVGEAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVRKMFE-------- 121
             + +    G   Y+              L+ Q K  +D+  R  +     E        
Sbjct: 64  IPMHFFNYYG--YYSGSFLPRKKNVSGSLLVEQVKHHIDDSKRQMLAISFIEGAVHHILR 121

Query: 122 ---------LRFGEPAP-------ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRY 165
                      F              +++E+L  IEG+     Y L         +    
Sbjct: 122 NLRKSGISVENFQNIEKDLLPKIFETKTIEELMAIEGNIREHYYQLFNTVIKNK-DFFIE 180

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADII 223
             +     + IN  IS   S +Y      I      P I ++H+   K  S   DIA+I 
Sbjct: 181 KREKRPPTNPINALISFGNSIMYNTVLTEIYRTQLDPTISYLHSPQEKRFSLSLDIAEIF 240

Query: 224 KFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           K   + P  F + +      D +        + +     K +   E+ L+     
Sbjct: 241 KPFIIDPLIFNLIKTGQITID-DFDKDLNYTYLNENGRKKFLKAYEERLSKTVKH 294


>UniRef50_B9YDC3 Putative uncharacterized protein n=1 Tax=Holdemania filiformis DSM
           12042 RepID=B9YDC3_9FIRM
          Length = 343

 Score =  207 bits (526), Expect = 6e-52,   Method: Composition-based stats.
 Identities = 38/311 (12%), Positives = 95/311 (30%), Gaps = 46/311 (14%)

Query: 11  LKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           ++   + +++      + +     V++++  +   IP+ +++ I++     +S A +   
Sbjct: 1   MRKIGNTLYITLPDVYLSLDGENVVILNQQKVIKRIPLHNLSSIVMFNYQGISPALMGKC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------- 119
                 L ++  AG  +                Q  ++ +    L + + M         
Sbjct: 61  MSQNITLSFLSPAGYFLGRVVGEYQGNVLLRKKQILVSENNQQSLLIAKNMILAKVYNSK 120

Query: 120 ---------FELRFG---------------EPAPARRSVEQLRGIEGSRVRATYALLAKQ 155
                    + LR                       +S ++LRG+EG+  +  ++     
Sbjct: 121 WILERAIRDYPLRIDIEKMRVIFKKLSEILNSIEKVQSHDELRGLEGTAAKLYFSSFDDL 180

Query: 156 Y-----GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG 210
                    +  R   P      + +N  +S   + L     +A+ + G    IGF H  
Sbjct: 181 ILRQKEDFVFTTRTRRPP----LNKVNALLSFVYTLLSHDCASALESVGLDCYIGFFHVD 236

Query: 211 KPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
           +P   S   D+ +  +          +  R   +           ++ +     K+I   
Sbjct: 237 RPGRMSLALDLMEEFRPCLADRFVLSLINRKEIDSCDFFDYENGAVYLNDDGRKKVIQAW 296

Query: 269 EDVLAAGEIQP 279
           +         P
Sbjct: 297 QLKKNEELTHP 307


>UniRef50_B7IHY4 Cas crispr-associated protein Cas1 n=4 Tax=Bacteria
           RepID=B7IHY4_THEAB
          Length = 330

 Score =  206 bits (525), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 49/291 (16%), Positives = 94/291 (32%), Gaps = 39/291 (13%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
           +     G++   D         G +  +P+ ++  + +     ++   +  A++ G L+ 
Sbjct: 5   IYIFNSGELKRKDNTICFESSEGKKY-LPIENINNLWIFGEVELNKRFLDFASENGILIH 63

Query: 77  WVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------------FE 121
           +    G        +        +L QA+  LD + R+K+ RK               ++
Sbjct: 64  FFNFYGYYTGTFYPREHLNSGFVILKQAEHYLDNEKRIKLARKFVEGAVENLLVVLKYYK 123

Query: 122 LR---FGEPAP----------ARRSVEQLRGIEGSRVRATYALLAKQYG---VTWNGRRY 165
            R     +             + + VE L   EG+     Y    K        +  R  
Sbjct: 124 NRGYELEDEIDDIKNKKEGIYSSQDVETLMSFEGNIRDIYYKCFDKITKKEEFAFEKRSR 183

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADII 223
            P      + +N  IS   S LY      I      P IG++H+   +  +   D+A+I 
Sbjct: 184 RPP----LNKMNSLISFGNSLLYTTVLGEIYQTQLDPRIGYLHSTNNRRFTLNLDVAEIF 239

Query: 224 KFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
           K   V    F +  +N     ++       I  ++    K I      L  
Sbjct: 240 KPSIVDRVIFSLVNKNVLSS-KDFDKQLNGIVLNNSGKKKFIEEYNKKLET 289


>UniRef50_D2NTT1 Uncharacterized protein predicted to be involved in DNA repair n=2
           Tax=Rothia mucilaginosa RepID=D2NTT1_9MICC
          Length = 560

 Score =  206 bits (525), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 50/295 (16%), Positives = 88/295 (29%), Gaps = 40/295 (13%)

Query: 18  IFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVW 77
           +  Q  +  V  G  ++       + +P+  V  +++     VS A +R        ++W
Sbjct: 237 LTTQGSRATVQQGRLIVQHLGETISSVPLERVHSLVVHGNIDVSSALLRELMWRNCTIIW 296

Query: 78  VGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA--------- 128
               G RVY   QPG   +     Q +  L     L +   M   +    A         
Sbjct: 297 CSSTG-RVYGWSQPGTGPNGLARVQ-QHVLSAQGYLPIASAMIASKIANQATLLRRNGHA 354

Query: 129 --------------PARRSVEQLRGIEGSRVRATYALLA--------KQYGVTWNGRRYD 166
                         P   S+ +L G+EG      +   A         + G  W GR+  
Sbjct: 355 ADVCRTMRDIQKNTPQATSIPELLGLEGEAASLYFGNFATMLKEDALTELGWIWTGRQGR 414

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIK 224
                  D IN  ++ A   L       IL  G  P  GF+H+      +   D+ +  +
Sbjct: 415 ----GANDPINILLNYAYGMLSSECIRGILTCGLDPHAGFLHSSSRNKPALALDLMEEFR 470

Query: 225 FDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                     +  R   +      +       + +    +I   E  +      P
Sbjct: 471 AVIADSVVVSLINRKQVKAAHFTTVGGSYR-LTPEGRKTIIAAFEKRMVTEITHP 524


>UniRef50_Q1CWU5 CRISPR-associated protein Cas1 n=1 Tax=Myxococcus xanthus DK 1622
           RepID=Q1CWU5_MYXXD
          Length = 342

 Score =  204 bits (520), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 43/293 (14%), Positives = 88/293 (30%), Gaps = 43/293 (14%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            I  +  +++      V+  +   +  +P+  +  ++      ++   +    + G  + 
Sbjct: 9   FITAEGTRLNKEGECVVVTVQDQKKAEVPLRHLRSVVCLTRAWLTPELMESCLEAGIHVS 68

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF---------------- 120
           + G  G  +       G        Q + A D    + + R +                 
Sbjct: 69  FFGMTGRFLARVEGVPGGNVLLRRQQYRAADDIARSVAISRALVVGKLGNARQFVLHARR 128

Query: 121 -------------ELRFGEPAPARRSVEQL---RGIEGSRVRATYALLAKQY-----GVT 159
                          R  E   A   VE L   RG+EG   R  +            G  
Sbjct: 129 DAAPERQEALSETARRLSEHLRALTRVEDLVQVRGLEGIAARDYFESFPALLKKSAQGFE 188

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVY 217
           ++GR   P      + +N  +S   + L      A+   G  PA+GF+H  +P   S   
Sbjct: 189 FDGRNRRPPR----NPLNAMLSFGYALLAQDCAGALTGVGLDPAVGFLHEDRPGRLSLAL 244

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
           D+ +  +   V    F +  R   +P      +   +          +   ++
Sbjct: 245 DLMEEFRAPVVDRLVFSLVNRGQLKPGDFRTESAGAVLLKDDARKTFLVAYQE 297


>UniRef50_C0BZ41 Putative uncharacterized protein n=3 Tax=Clostridiales
           RepID=C0BZ41_9CLOT
          Length = 343

 Score =  204 bits (518), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 44/311 (14%), Positives = 100/311 (32%), Gaps = 46/311 (14%)

Query: 11  LKDRVSMIFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K  ++ +++      + +     V+++       +P+ ++  I+    T  S A +   
Sbjct: 1   MKKLLNTLYVTSTNRYLFLDGENVVILEDQEEIGRVPLHNLEGIVTFGYTGASPALMGAC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------- 119
           A+    L ++   G  +                Q +++  +   +K+ R           
Sbjct: 61  AERNIDLSFMSGNGRFLARVSGEVRGNVTLRKEQYRISEQKKESIKIARNFITGKVYNAK 120

Query: 120 ---------FELRFGEPAPARRS---------------VEQLRGIEGSRVRATYALLAKQ 155
                    + LR        +S                E+L GIEG      +++  + 
Sbjct: 121 WVLERAARDYPLRLDVDRIKEKSAFMSGNLPKIRECEDAERLLGIEGESASLYFSVFDEL 180

Query: 156 Y-----GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG 210
                   ++ GR   P      D +N  +S A + L G+  +A+ + G  P +GF HT 
Sbjct: 181 ILQQKDEFSFGGRNKRPP----LDNVNAMLSFAYTLLTGMCASALESVGLDPYVGFYHTD 236

Query: 211 KPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
           +P   S   D+ + ++          +  +         +     +     T  + +   
Sbjct: 237 RPGRVSLALDLMEELRSVMADRFVLTLINKKIIGASGFSKKESGAVIMDDDTRRQFLSHW 296

Query: 269 EDVLAAGEIQP 279
           +D        P
Sbjct: 297 QDKKKETITHP 307


>UniRef50_B0K547 CRISPR-associated protein Cas1 n=12 Tax=Bacteria RepID=B0K547_THEPX
          Length = 330

 Score =  203 bits (517), Expect = 6e-51,   Method: Composition-based stats.
 Identities = 53/298 (17%), Positives = 97/298 (32%), Gaps = 39/298 (13%)

Query: 14  RVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
           + ++     G++   D       + G +  IPV + + IM+     ++   +    Q   
Sbjct: 2   KKTIYIFSDGELKRKDNTLFFEGENGRKF-IPVENTSEIMVFGEVSLNKRLLEFLTQSEI 60

Query: 74  LLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------- 121
           +L +    G  V +   +        +L QA+   D   RL + +K  E           
Sbjct: 61  ILHFFNHYGYYVGSYYPREHLNSGYMILRQAEHYNDGSKRLYLAQKFVEGAYKNIRQVLK 120

Query: 122 ----------------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY---GVTWNG 162
                            + GE   +  ++ +L  IEG+     Y    +        ++ 
Sbjct: 121 YYSNRGKDLEDVIYSIEKLGESVDSTSTINELMAIEGNIREYYYKAFDEIIQNPDFKFDF 180

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIA 220
           R   P      + +N  IS   S +Y  T + I      P IGF+H    +  S   D++
Sbjct: 181 RSKRPPQ----NFLNTLISFGNSLMYTTTLSEIYKTHLDPRIGFLHATNFRRFSLNLDVS 236

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           +I K   V    F +  +     +     A   +    K     +   ED LA     
Sbjct: 237 EIFKPIIVDRTIFTLLSKKMVTKEDFEEDAE-GLLLKEKGKKVFVQEFEDKLATTIKH 293


>UniRef50_O57912 Putative uncharacterized protein PH0173 n=1 Tax=Pyrococcus
           horikoshii RepID=O57912_PYRHO
          Length = 317

 Score =  202 bits (515), Expect = 9e-51,   Method: Composition-based stats.
 Identities = 55/302 (18%), Positives = 110/302 (36%), Gaps = 29/302 (9%)

Query: 16  SMIFL-QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
           S I++ Q G ++        +++  ++  +P+ +++ I       ++  A++L +     
Sbjct: 3   SPIYITQPGILERKANTLFFVNE-EMKRALPINTISEIHCFAPVTLTSGAIKLLSDNDVP 61

Query: 75  LVWVGEAGVRVYASGQPGGA-RSDKLLYQAKLALDEDLRLKVVRKMFE------------ 121
           + +  + G    +            ++ QA   +D + RL + R++ E            
Sbjct: 62  VHFYNKYGYYRGSYLPAESQISGSIVVAQASHYIDNEKRLYIAREILEGTRASMISLLKS 121

Query: 122 -----LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGV-TWNGRRYDPKDWEKGDT 175
                    +      S+E+L GIE    +  YA  +       ++ R   P      D 
Sbjct: 122 QRAEYKDLADIDLKGESIEELMGIESQLWKTFYAHFSHLLKFFNFDERNRRPPR----DE 177

Query: 176 INQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAF 233
           IN  IS   S LY VT + I      P I ++H  +    S   D+A+I K   V     
Sbjct: 178 INAMISYGNSVLYTVTLSEIRKTYLHPGISYLHEPRERRYSLALDLAEIFKPIVVFRVIL 237

Query: 234 EIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPL 293
            +  +     +  VR     +  +S+ +   +  I D L+   + P    + +    I L
Sbjct: 238 RLVNKRIIREEHFVRD--VGVLLNSEGVKIFLGGINDELSRKVLHPTLRRKVSVRYLIRL 295

Query: 294 PV 295
             
Sbjct: 296 EA 297


>UniRef50_A1A2M8 CRISPR-associated DNA polymerase n=14 Tax=Bacteria
           RepID=A1A2M8_BIFAA
          Length = 343

 Score =  202 bits (515), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 44/311 (14%), Positives = 93/311 (29%), Gaps = 46/311 (14%)

Query: 11  LKDRVSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K  ++ +F+  +   + + +   V+         +P+ S+  IM       S A +   
Sbjct: 1   MKQLLNTLFVMTEDAYLALENDNVVIYQNDQTLAKVPLRSIEGIMCFSYKGASPALMGRC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE-- 126
            ++G  + +    G    +              Q ++A DE   L+  +     +     
Sbjct: 61  GKLGVSMAFYSPRGHYYCSVLGEENRNVLLRREQFRVADDEQKSLRYAKSFIVGKLYNAK 120

Query: 127 -------------------------------PAPARRSVEQLRGIEGSRVRATYALLAKQ 155
                                           A    ++++LRG+EG   +  +      
Sbjct: 121 WVLERTKRDHALRVNIDRLAEQSGKLSAALSKARKSLTIDELRGVEGLAAKDYFYAFDDL 180

Query: 156 Y-----GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG 210
                    +  R   P      D +N  +S   S L     AA+   G  P +GF+HT 
Sbjct: 181 VLKNKDDFFFTSRSRRPP----LDRLNALLSFCYSILTNDCIAALQGVGLDPYVGFMHTD 236

Query: 211 KPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
           +P   S   D+ +  +          +      +P          +  S     K++   
Sbjct: 237 RPGRASLALDLVEEFRPVLADRFVLTLVNTGAVKPGDFEIRENGGVLLSDFGRKKVLTAW 296

Query: 269 EDVLAAGEIQP 279
           +   +   + P
Sbjct: 297 QKKKSDQILHP 307


>UniRef50_A7HNI6 CRISPR-associated protein Cas1 n=1 Tax=Fervidobacterium nodosum
           Rt17-B1 RepID=A7HNI6_FERNB
          Length = 334

 Score =  202 bits (514), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 44/296 (14%), Positives = 97/296 (32%), Gaps = 39/296 (13%)

Query: 15  VSMIFLQYGQ-IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
           +++  L+ G  +   DG  ++     +   IP+  +  I L     ++   +        
Sbjct: 1   MTIYVLEQGTVLAKKDGRMIITKAKQVLDEIPLKKIERINLLGNITLTSQMINYCLDNKI 60

Query: 74  LLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG-------- 125
            ++++ + G                 L Q + A D+  +L++ + + + +          
Sbjct: 61  EVIFMTQHGRYRGKLYTDEYRNVLLRLKQYERATDKQFQLEISKSIVQGKLQNYYNFLTQ 120

Query: 126 ---------------------EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVT---WN 161
                                E     ++V+++RG EG   +  ++   K        +N
Sbjct: 121 KSKNLPKGLLSEERAGIRTVIEKVNKAKTVDEVRGYEGIGSKIYFSGFKKCIRTEELTFN 180

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDI 219
           GR   P      D IN  +S     LY     AI A G  P  G +HT      S ++D+
Sbjct: 181 GRTAHPPK----DEINAMLSLGYYFLYVEMLLAINAVGLDPYFGNLHTIDVSKQSLLFDL 236

Query: 220 ADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
            +  +   +      +      + +   +      + +   + K I   E ++   
Sbjct: 237 VEEFRCVIIDNFVLNLINLKTIKKEDFEKRENDIYYFTKDGMKKYITEYEQMMKQK 292


>UniRef50_C9LM09 CRISPR-associated protein Cas1 n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LM09_9FIRM
          Length = 331

 Score =  201 bits (511), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 42/300 (14%), Positives = 88/300 (29%), Gaps = 35/300 (11%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S I++     +++   G +V+  +      +P   V  + L    ++S + +    +  
Sbjct: 1   MSWIYVTEPGAKLNRQGGRYVISRENETICEVPSAVVEGVTLFDSIQISSSVIVDFLERN 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM------------- 119
             L W+   G               +   Q     D+D  L + +++             
Sbjct: 61  IPLTWISSTGRFFGRLESTDHQNVLRQKEQFDALADKDFCLALAKRVVFGKVYNQRTILR 120

Query: 120 -FELR---------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGR 163
            +  R                 +      SVE++ G EG   R  +  +       +  R
Sbjct: 121 NYNRRAEDPFIEKVRSDIRILADKLHMAHSVEEVMGYEGMMARIYFQAIGHILPEEF--R 178

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIAD 221
                     D  N  +S   + L     +AI+  G  P IGF+H  +    +   D+ +
Sbjct: 179 FEKRTKRPPRDYFNSLLSFGYTLLMYDFYSAIVNCGLHPYIGFLHALRNGHPALASDLME 238

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPA 281
             +   V      +        D  V+     I+ +       +   E  +         
Sbjct: 239 PWRPAVVDAFCLSLVTHREISKDYFVKGENGGIYLNRIGRRIFLQAYERKMRTVNRYFQG 298


>UniRef50_Q2SIC8 CRISPR-associated protein Cas1 n=6 Tax=Gammaproteobacteria
           RepID=Q2SIC8_HAHCH
          Length = 338

 Score =  200 bits (510), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 41/306 (13%), Positives = 87/306 (28%), Gaps = 41/306 (13%)

Query: 11  LKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K   + +++      +       V+          P  +VA I       VS   +   
Sbjct: 1   MKKLQNSLYVTRQESYLHKERETIVIKQGKDKLAQFPAHAVANIFCFGQISVSPFLMGYC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA 128
            + G  LV+  E G  +                Q +++  +  RL + R +   +     
Sbjct: 61  GEQGIGLVFFTEYGKFLARIQGRQSGNVLLRREQYRVSDKDTPRLDIARSIVLAKIANSR 120

Query: 129 ------------------------------PARRSVEQLRGIEGSRVRATYALLAKQY-- 156
                                             +++ LRG+EG      + +  +    
Sbjct: 121 RVLQREVRNKGAHPSLDEAIARLANCLRRCERPDNLDILRGLEGEAAAIYFGVFNQLLKQ 180

Query: 157 -GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL-- 213
            G  + GR   P      D +N  +S   + +     +A+   G  P +G++H  +P   
Sbjct: 181 DGFDFKGRVRRPP----TDPVNALLSFLYTLVAQEISSALQGVGLDPYVGYLHVDRPGRV 236

Query: 214 SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
               DI +  +          +  R   +       A   +        K++   ++   
Sbjct: 237 GLALDILEEFRAWWCDRLVLTLINRKEVKASDFDIEASGAVRLKEDARRKVLVAYQEKKQ 296

Query: 274 AGEIQP 279
                P
Sbjct: 297 EEISHP 302


>UniRef50_B1X158 DUF48-containing protein n=12 Tax=Cyanobacteria RepID=B1X158_CYAA5
          Length = 330

 Score =  200 bits (509), Expect = 5e-50,   Method: Composition-based stats.
 Identities = 39/319 (12%), Positives = 90/319 (28%), Gaps = 42/319 (13%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +  +++  Q   + +      +  K  +   I +  +  +++   ++++  A+R      
Sbjct: 1   MKTLYVSQQGCYVKLDQETLKVEKKRQLLAEIQLPLIEQVLIFGKSQMTTQAIRACLWRN 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG------- 125
             +V++   G                  YQ +L  D   RL   R++ + +         
Sbjct: 61  IPIVYLSRMGYCYGRIMSLKRGYRHLTRYQQQL--DFSQRLLTARELVKAKLKNCRVILQ 118

Query: 126 ----------------------EPAPARRSVEQLRGIEGSRVRATYALLAKQY---GVTW 160
                                 E A    ++E+L G EG      ++            +
Sbjct: 119 RQQRRLQSDKLLFAIDSLNYLIEQANLAETIERLMGFEGVGASTYFSAFGDCLTPSEFIF 178

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYD 218
             R   P     G+ +N  +S     L+    A I   G  P    +H G     +   D
Sbjct: 179 LARSRRPP----GNPVNAMLSFGYQVLWNHLLALIELQGLDPYQACLHQGSERHAALASD 234

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           + +  +   V      +  R     D +        + ++    K +      +      
Sbjct: 235 LIEEFRAPMVDSLVLYLVNRRIMNADDDFEYHDGGCYLNNTGRKKYLKHFVQRMEETVQT 294

Query: 279 PPAPPEDAQPVAIPLPVSL 297
            P   +    + +      
Sbjct: 295 TPDEKQPRWDLLMQQVKRY 313


>UniRef50_A1BI39 CRISPR-associated protein Cas1 n=5 Tax=Chlorobiaceae
           RepID=A1BI39_CHLPD
          Length = 731

 Score =  199 bits (506), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 42/300 (14%), Positives = 97/300 (32%), Gaps = 43/300 (14%)

Query: 15  VSMIFL-QYGQIDVIDG-AFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           ++ ++L + G +   DG  F +     +   + V  +  +++     ++   ++   Q  
Sbjct: 389 LNTLYLQEQGSLMRKDGERFSIEKDGSVINEVIVRRIEQVVIFGNVALTTPVMQYCLQNE 448

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE------ 126
             + ++ + G             ++   +    ++DE   L+  R +   +         
Sbjct: 449 IPVTFLSQHGKYFGRLEATTADNAEMQRFHFLRSIDEPFALETARSIVAAKISNSKTMIR 508

Query: 127 -----------------------------PAPARRSVEQLRGIEGSRVRATYALLAKQY- 156
                                         A A   ++ LRGIEG      +      + 
Sbjct: 509 RRKTVVQDRDSTLQNKMAYNLDIMADLALKAEASTDIDALRGIEGKASALYFECYGMLFS 568

Query: 157 -GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL-- 213
             + ++ R +        D +N  +S   + L+    + + A+G  P IGF+H  +    
Sbjct: 569 KNLPFHTRSFLRVRRPPTDPVNSLLSFGYTMLHTNIFSMVQASGLNPYIGFLHAERKGNP 628

Query: 214 SFVYDIADIIKFDTVVPKAFEIARRNPG-EPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
           + V D+ +  +   V         R    E D   R      F S+    + + + E  +
Sbjct: 629 ALVNDLVEEFRT-IVDSLVLYTLNRGLLQEKDFYYRKDEPGCFLSNDARKRFLNIFETRM 687


>UniRef50_C2GEC7 Crispr-associated protein Cas1 n=2 Tax=Corynebacterium
           RepID=C2GEC7_9CORY
          Length = 533

 Score =  198 bits (504), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 50/295 (16%), Positives = 88/295 (29%), Gaps = 40/295 (13%)

Query: 18  IFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVW 77
           + +Q  +  + +G  ++          P+  V  +++     +S A  R        +VW
Sbjct: 210 LTVQGSRASIRNGRVIVEKAGERLADAPLERVQGVVIHGNVDISSALHRNFLWHNVPVVW 269

Query: 78  VGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA--------- 128
               G RVY    P    +     Q +  L     L + R M   +    A         
Sbjct: 270 CSTTG-RVYGYSCPTDGPNAAARVQ-QHVLSSRGCLPIARGMVNAKIMNQATLLRRNGDS 327

Query: 129 --------------PARRSVEQLRGIEGSRVRATYALLA--------KQYGVTWNGRRYD 166
                            +   QL GIEG      ++  +         Q G TW GR   
Sbjct: 328 DRTVQLLIDAGTCSLEAKDNRQLFGIEGDAAALYFSTFSTMLNKAQIDQLGWTWTGRHGR 387

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIK 224
                  D IN  ++ +   L      A+L+ G  P  GF+H+      +   D+ +  +
Sbjct: 388 ----GASDPINILLNYSYGLLRAEVIRALLSCGLDPHAGFLHSSGRNKPALALDLMEEFR 443

Query: 225 FDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                     +  R   +      +      R +    K+I   E  +      P
Sbjct: 444 APVSDSVVISLINRREIKDTDFTHIHGVARLRDT-GRKKIIRAFERRIQTSIKHP 497


>UniRef50_Q2RY11 CRISPR-associated protein, Cas1 family / CRISPR-associated
           exonuclease, Cas4 family n=2 Tax=Rhodospirillum rubrum
           ATCC 11170 RepID=Q2RY11_RHORT
          Length = 580

 Score =  198 bits (504), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 46/295 (15%), Positives = 84/295 (28%), Gaps = 43/295 (14%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
            +I   D   V+  +      + +  ++ ++L     ++  A+    +    + W+    
Sbjct: 255 ARIGKKDYTLVIQVEGEADRSLALDEISEVVLAGPVSLTTPAIHELLRREIPVAWMSSGF 314

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE--------------------- 121
             + ++G  G   +     Q  LA DE  R    R +                       
Sbjct: 315 WFLGSTGGQGPRSAAVRTAQYALAGDERRRQAFARDLVSAKIRNGRTLLRRNWRGAEAER 374

Query: 122 -------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQY--------GVTWNGRRYD 166
                   R  E A    +   L GIEG      +    + +           +  R   
Sbjct: 375 QIALDRLARLAERATTAETTACLLGIEGEAAAVYFRAFPQLFTQAVTTLPAFAFERRNRR 434

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIK 224
           P      D +N C+S   + L     +A+  AG  P  GF HT +P   +   D+ +  +
Sbjct: 435 PP----ADPVNACLSLCYAVLTRTLSSALSIAGLDPWKGFYHTERPGRPALALDLIESFR 490

Query: 225 FDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                     +        + +   A             LI   E  L      P
Sbjct: 491 PVLADSTVLMVLNNGEIGTN-DFLYAGGGCALKPNARRGLIAAYERRLDQETTHP 544


>UniRef50_C0QR16 Crispr-associated protein Cas1 n=23 Tax=Bacteria RepID=C0QR16_PERMH
          Length = 331

 Score =  198 bits (504), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 42/300 (14%), Positives = 85/300 (28%), Gaps = 38/300 (12%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGI---RTHIPVGSVACIMLEPGTRVSHAAVRL 67
           +  R        G++   +       +      +  +P+  +  I +     ++  A+  
Sbjct: 1   MSRR--FYINSNGRLRRKENTLYFETEQNGEIVKKALPINDIDVIYVFGELDINTKALNY 58

Query: 68  AAQVGTLLVWVGEAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVRKMFE--- 121
            +     + +    G   Y+              L+ Q +  +D   R  +     E   
Sbjct: 59  LSGYDIPIHFYNYYG--FYSGSFLPRKKNVSGSLLVEQVRHYIDNKKRQYLAVSFVEGAA 116

Query: 122 ----LRFGEPAP-----------------ARRSVEQLRGIEGSRVRATYALLAKQYGVTW 160
                   +                      R+ E+L  +EG+     Y L  K      
Sbjct: 117 YHILRNLRKQNINSEDFEEIEKDLFPKIFETRNTEELMALEGNIRERYYQLFNKIINNE- 175

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYD 218
           +      +     + IN  IS   S +Y      I      P I ++HT   K  S   D
Sbjct: 176 DFFMEKREKRPPDNPINALISFGNSIMYNTVLTEIYRTQLDPTISYLHTPQEKRFSLSLD 235

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           +A+I K   + P  F +         ++        + +     K +   E+ L+     
Sbjct: 236 LAEIFKPFIIDPLIFSLINNRQITI-KDFDKDLNYAYLNENGRKKFLKAYEERLSKTIKH 294


>UniRef50_D0LSW9 CRISPR-associated protein Cas1 n=1 Tax=Haliangium ochraceum DSM
           14365 RepID=D0LSW9_HALO1
          Length = 594

 Score =  198 bits (503), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 45/307 (14%), Positives = 85/307 (27%), Gaps = 38/307 (12%)

Query: 6   LNPIPLKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
              + L+D    + +Q     +       V+  K      + +  V+ I L     ++  
Sbjct: 257 RPLVSLRDDALPLHVQEHGAVVSKRAAELVIKRKGSELERVRIKDVSRINLHGSAHITLP 316

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
           A++ A   G  +      G     +             Q   A DE   L++ +++   +
Sbjct: 317 ALQTALGNGIPVGLFTYGGWYYGRAQGHDHKNVLLRQAQFASAQDEGRCLRIAQRLVHAK 376

Query: 124 FGEPAP-------------------------ARRSVEQLRGIEGSRVRATYALLA----K 154
                                             S   L GIEGS  R  +   +    +
Sbjct: 377 IKNSRVMLRRNSRALDRRILDDLSGHARRARQADSQATLLGIEGSAARLYFQNFSGMLRQ 436

Query: 155 QYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--P 212
               +++ R   P      D +N  +S + + L     A +   G+ P  GF H  +   
Sbjct: 437 DVPFSFDSRNRRPPR----DPVNALLSFSYALLTAEWTATLSTVGFDPYQGFYHQPRYGR 492

Query: 213 LSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
            S   D+ +  +                 + D  V  A            + +   E  L
Sbjct: 493 PSLALDLMEEFRPLIADSVVIGAINNGVLDEDDFVVTATAAA-LKPAGRKRFLQAFERRL 551

Query: 273 AAGEIQP 279
                 P
Sbjct: 552 DEQVTHP 558


>UniRef50_A7HMV0 CRISPR-associated protein Cas1 n=3 Tax=Thermotogaceae
           RepID=A7HMV0_FERNB
          Length = 329

 Score =  198 bits (503), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 50/303 (16%), Positives = 102/303 (33%), Gaps = 41/303 (13%)

Query: 15  VSMIFL-QYGQIDVIDGAFVLI--DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +  +++ +   +     A  +    +     ++P+ +++ IM+     ++   + L +  
Sbjct: 1   MEALYVFKDSYLRKKSSALYIEPKSEDQKPIYVPLKNISSIMVFSEIEMNKKTLELFSYS 60

Query: 72  GTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKM----------- 119
              + +    G  +            + LL Q +   D + R+ + R++           
Sbjct: 61  QVPVFFFNYNGEYIGCFYPVEENKTGEMLLLQLQHYQDLEKRIIIAREILYGVADNILKI 120

Query: 120 ---FELRFGEPAPARRSVE-------------QLRGIEGSRVRATYALLAKQY---GVTW 160
              ++  F E       +E              L  IEG+  +  Y  L   +     T+
Sbjct: 121 LKSYKNDFPEINEKIEMIEKLKKTYHRQEEIASLMAIEGNIRKNYYEALGVIFSKKDFTF 180

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYD 218
             R   P      D IN  IS   + LY V  + I      PAI F+H       S   D
Sbjct: 181 QERTARPP----ADEINAMISFGNTILYNVVLSEIFKTSLEPAISFLHEPNKRKFSLQLD 236

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           IA+I K   V      +  R+  + D + +     ++ +     K +  +E+ L+     
Sbjct: 237 IAEIFKPIIVDRTILTLVNRSMIKKD-DFKKVEGGVYLNETGKKKFVKALEEKLSETIDY 295

Query: 279 PPA 281
              
Sbjct: 296 ENG 298


>UniRef50_A1HM55 CRISPR-associated protein Cas1 n=2 Tax=Thermosinus carboxydivorans
           Nor1 RepID=A1HM55_9FIRM
          Length = 332

 Score =  197 bits (500), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 48/294 (16%), Positives = 93/294 (31%), Gaps = 40/294 (13%)

Query: 15  VSMIFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +  +++      I    G F++     I   IP+  +  ++L    +VS   +    + G
Sbjct: 1   MRTLYVTDAGSHIQKNAGRFLVCKGDTILREIPLELLDNVVLFGSIQVSAKTITEFLKRG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG------- 125
             L W+ + G                   Q ++    D  LK+ + + + +         
Sbjct: 61  ITLTWLSKTGEFYGRLESTRHIDIFLHRQQIRMGDRPDFCLKIAQAIIDAKIANCMTILR 120

Query: 126 ----------------------EPAPARRSVEQLRGIEGSRVRATYALLAKQYG--VTWN 161
                                 E  P    +E L G+EGS  R  +  LA        + 
Sbjct: 121 RYQRTANSPEVADHIHAMGIIAEKIPNVDKIETLLGLEGSAARHYFTALACLVPDDFAFK 180

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDI 219
           GR   P      D  N  +S   + L       +  AG  P  GF+H  +    + V D+
Sbjct: 181 GRNKQPPK----DPFNSLLSFGYTLLMYDFYTIVQNAGLHPYAGFLHKDRQGHPTLVSDL 236

Query: 220 ADIIKFDTVVPKAFEIARRNPGEPDREV-RLACRDIFRSSKTLAKLIPLIEDVL 272
            +  +   +      +  R   +P   +       ++ + +  A+ I   E  +
Sbjct: 237 MEEWRPSIIDSLVMSLIHRREIQPLDFLPPDKNGGVYLNREASAEFIAAYEKRM 290


>UniRef50_A5D0Y0 Uncharacterized protein n=40 Tax=cellular organisms
           RepID=A5D0Y0_PELTS
          Length = 344

 Score =  196 bits (499), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 50/314 (15%), Positives = 93/314 (29%), Gaps = 39/314 (12%)

Query: 14  RVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
           + ++     G++   D       + G R  IPV     IM+     V+   +   +    
Sbjct: 16  KKTLYIFSNGELSRKDNTLYFETEEGRRF-IPVEDTGEIMIFGEVDVNKKLLEFLSVKEI 74

Query: 74  LLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------- 121
            L +    G  + +   +         L QA+  LDE+ RL + +++             
Sbjct: 75  TLHFFNYHGYYMGSFYPREHLNSGYMTLKQAEHYLDEEKRLVIAKEIVRGAAKNIRQVLK 134

Query: 122 ----------------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG---VTWNG 162
                                P    R    L  +EG+     Y    +        +  
Sbjct: 135 YYYGREKDVGGKLNAIENLMAPIEECRDTSSLMALEGNIRDHYYRAFDEIVDNPDFAFQE 194

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIA 220
           R   P      + +N  IS   S +Y +  + I      P IG++H    +  +   DIA
Sbjct: 195 RSRRPPK----NYLNTLISFGNSLIYTICLSEIYKTHLDPRIGYLHATNFRRFTLNLDIA 250

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
           +I K   V    F +  +     + +       I    K     +  +++ L        
Sbjct: 251 EIFKPIIVDRLIFTLLGKKMITKE-DFDRGTEGIMMKEKARKCFVENLDEKLKTTINHRE 309

Query: 281 APPEDAQPVAIPLP 294
                +    I L 
Sbjct: 310 IGRPVSYRRLIRLE 323


>UniRef50_A9AYP8 CRISPR-associated protein Cas1 n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9AYP8_HERA2
          Length = 333

 Score =  195 bits (497), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 54/309 (17%), Positives = 104/309 (33%), Gaps = 43/309 (13%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVA-CIMLEPGTRVSHAAVRLAAQV 71
           +  ++L  Q  ++   D   +++    +   IPV  V   I++  G +VSHAA+   AQ 
Sbjct: 1   MPTLYLNEQGTRLGKKDERLIILRGQELINDIPVIKVDRVIVMGQGVQVSHAAIVFLAQR 60

Query: 72  GTLLVWVGE-AGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP- 129
           G  L++  +  G +        G  +   L Q ++  +  L + +V+ +   +       
Sbjct: 61  GIPLIFTTQSGGSQKAMVSAGLGNNAALRLAQCRIVDNPHLAVPLVQAIVVGKVANQIQL 120

Query: 130 ---------------------------ARRSVEQLRGIEGSRVRATYALLAKQYGVTWN- 161
                                          +EQLRG+EG+   A +   +  +   W  
Sbjct: 121 LERYGSDWGGMGLRAKQTMQHVIQQTQHMPDIEQLRGLEGAGAAAYWGTWSAVFKTAWGF 180

Query: 162 -GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVY 217
            GR Y P      D +N  +S   + L      A+ A  + P +G  HT   G+P S   
Sbjct: 181 AGRAYRPTP----DPLNALLSFGYTLLLNDLMTAVQALSFDPYLGVFHTVQFGRP-SLAL 235

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           D+ +  +   V     ++      +         +    + +     I   E  +     
Sbjct: 236 DLEEEFRPCIVDRMVLDVLDAGLLQM-SNFSRTEKGFLLNDRARKSFIQAYEQRMQTPIR 294

Query: 278 QPPAPPEDA 286
                  + 
Sbjct: 295 YQGTGNNEP 303


>UniRef50_C1XWQ6 CRISPR-associated protein, Cas1 family n=3 Tax=Thermaceae
           RepID=C1XWQ6_9DEIN
          Length = 326

 Score =  195 bits (497), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 45/292 (15%), Positives = 87/292 (29%), Gaps = 34/292 (11%)

Query: 17  MIFLQYGQIDVIDGAFVLID----KTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +  L+ G +    G   +              P+  V  I++     V+ A ++  A+  
Sbjct: 4   VYVLEDGYLAKDGGTLKVSKRGPGGGETLLEKPLIGVEEIVVLGNAVVTPALLKHCAEEN 63

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE------ 126
             L +V   G       +     +   + Q    LD   +L + R+    +         
Sbjct: 64  IGLHYVSTGGRYFAGLTRTPAKNAPARVAQFAAHLDPTRKLALARRFVLGKLRNSLTLLR 123

Query: 127 ---------------PAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKD 169
                                    LRG+EG+     +   A     G  ++ R   P  
Sbjct: 124 RNGAEGWEEIRWAIGELDKAADEGALRGLEGNAADVYFRSYAALLPEGFRFSERSRRPPR 183

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFDT 227
               D  N  +S A + L    E+A+  AG  P +G++H  +    S   D+ +  +   
Sbjct: 184 ----DPANSLLSLAYTFLAKECESALQVAGLDPYVGYLHEVRYGRASLALDLMEEFRSIL 239

Query: 228 VVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                  +        + +   A        ++  K +   E+ L      P
Sbjct: 240 ADSVVLSLLNNRRLTLE-DFDDAEGYPKLRKESFPKFLRAWEERLTDRVRHP 290


>UniRef50_A5UXM3 CRISPR-associated protein, Cas1 family n=4 Tax=Chloroflexaceae
           RepID=A5UXM3_ROSS1
          Length = 332

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 47/302 (15%), Positives = 94/302 (31%), Gaps = 39/302 (12%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQV 71
           +  +++Q     +   D   ++       + +P+  +  ++L   G ++S A +    + 
Sbjct: 1   MPTLYIQEQGVMVRKRDNQVLITKDGQTLSEVPLAKIDQVVLMGRGVQLSTALLIDLLER 60

Query: 72  GTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA-- 128
           G  + +  + G R YA+         D  + Q +     D  L++ + +   +       
Sbjct: 61  GIPVTFTNQHGSRHYATLTAGPSRFGDLRIRQMQFVGAPDRALRLAKDIVSAKLTNQRRL 120

Query: 129 ------PARRS-----------------VEQLRGIEGSRVRATYALLAKQYGVTWN--GR 163
                 PA  +                 V+ LRG EG+   A +          W   GR
Sbjct: 121 LAATGWPAAATAIAQIDAALTAAANAPHVDMLRGHEGAAAAAYFGAWRASLPPVWGFGGR 180

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIAD 221
            + P      D IN  +S   +        A+   G    +G  H       S   D+ +
Sbjct: 181 AFYPPP----DPINAMLSFGYTLALHDVITAVQITGLDTYLGVFHVIEPGRPSLALDLLE 236

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACR--DIFRSSKTLAKLIPLIEDVLAAGEIQP 279
             +   V     ++ R N    +       R   ++        L+   E +L      P
Sbjct: 237 EFRPLIVDRLVIDLVRTNAIGREHFHHPQERPDAVYLDDVGRTLLVQRYESMLQTKVRLP 296

Query: 280 PA 281
             
Sbjct: 297 GG 298


>UniRef50_C9M4Y8 CRISPR-associated protein Cas1 n=1 Tax=Jonquetella anthropi E3_33
           E1 RepID=C9M4Y8_9BACT
          Length = 342

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 48/310 (15%), Positives = 89/310 (28%), Gaps = 45/310 (14%)

Query: 11  LKDRVSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K   + ++L    GQI     A V+  K       PV  +  I+      ++  A+ L 
Sbjct: 1   MKQLKNTLYLSYDEGQISCSGRALVIRAKDQAPQQFPVHILEQIVCFGSVMLTPDAMNLC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM--------- 119
                 + ++   G        P          Q + A D     ++             
Sbjct: 61  LANNVTINYLSVYGRFRGRISGPVRGNVLLRRMQFRRADDPVQTAELATAFLLSKISNAR 120

Query: 120 -FELRFGEPAPAR---------------------RSVEQLRGIEGSRVRATYALLAKQY- 156
              LR                               + +LRG+EG      +        
Sbjct: 121 TVLLRHARERETNVFDEAVRDMAGLLVKLKGFTITDLNELRGLEGDAANIYFRCFDSMIL 180

Query: 157 ----GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKP 212
                 +++GR   P      D IN  +S   S L       + + G  P++GF+H  +P
Sbjct: 181 KNRETFSFHGRSRRPP----SDPINALLSLGYSLLAAEITGVLESVGLDPSVGFLHKDRP 236

Query: 213 L--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAK-LIPLIE 269
              S   D+ +  +   V      +  R   + +         +  + K   +  +   E
Sbjct: 237 GRPSLALDLMEEFRAVVVDRFVLALVNREQLQANDFETDEAGGVALTEKARKEIFLNEWE 296

Query: 270 DVLAAGEIQP 279
           +      I P
Sbjct: 297 NRKRTEIIHP 306


>UniRef50_D1BQ37 CRISPR-associated protein Cas1 n=1 Tax=Veillonella parvula DSM 2008
           RepID=D1BQ37_VEIPT
          Length = 331

 Score =  195 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 60/292 (20%), Positives = 106/292 (36%), Gaps = 37/292 (12%)

Query: 17  MIFL-QYGQ-IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
            +++   G  I    G  VL     +   IP+ +V+ ++L    ++S   +    + G+L
Sbjct: 4   TLYVMTPGISIRQDGGLLVLEKDHSVIKEIPIATVSNLVLGRTIQISTQVMFSLVKQGSL 63

Query: 75  LVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA------ 128
           + +V      V   G        +LL+Q     +++  L   + +   +           
Sbjct: 64  IQFVDHKYQLVGTLG-DEHTPLQRLLWQVACFQNQEFALDGAKYIVRRKIKGQIALLNQY 122

Query: 129 -----------------------PARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRY 165
                                     + VE LRGIEG   R  +++L       W     
Sbjct: 123 KKSKCIPNFVVVHRTMQALLKRVERTKKVETLRGIEGLASRTYFSVLGHVLSEPWEFSGR 182

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADII 223
                   D +N  +S   S L     A +L AG    IG +H+   +  S VYD+ DI 
Sbjct: 183 KR--HPSPDPVNAILSYGYSFLEREVRACLLTAGLDVRIGVLHSTNNRKDSLVYDVMDIF 240

Query: 224 KFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
           + D +     ++  R+   P+ +  L+ R  F S +   K + L ED + A 
Sbjct: 241 RQDIIDRFVLKLLNRHMILPE-DFDLSERGCFLSKEANKKWVELYEDYMKAE 291


>UniRef50_C0A724 CRISPR-associated Cas1/Cas4 family protein n=1 Tax=Opitutaceae
           bacterium TAV2 RepID=C0A724_9BACT
          Length = 691

 Score =  195 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 45/353 (12%), Positives = 93/353 (26%), Gaps = 84/353 (23%)

Query: 6   LNPIPLKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
              +  +D    +++      +        + +K  +   I +  ++ + +     +S A
Sbjct: 308 RRLVAARDDERELYITTPGTTLLKKSELIQIREKGELVNEIRIKDLSHVAIFGSATISTA 367

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
            +   A+    + +   AG     +  P        + Q + A      L++ R   + +
Sbjct: 368 LLNELAERDIAVSYFSSAGTLRAYTRGPSLKNVFTRIAQFRAADTPATALRIARLFVQGK 427

Query: 124 FGEPAP-------------------------ARRSVEQLRGIEGSRVRATYALLA----- 153
                                             S+E+L GIEGS   A +   +     
Sbjct: 428 IRNQRTLIMRNHAMPPASTLGRLQHAITAAANTESIEELLGIEGSAALAYFQEFSGMIKT 487

Query: 154 ---------------------------------------------KQYGVTWNGRRYDPK 168
                                                        + +   +  R   P 
Sbjct: 488 TGDDILDAIAEGREPEPGSLSDTTQAPDITTGKKRRSGKRDTPGQEFFSFDFTRRNRRPP 547

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFD 226
                D +N  +S A S L     +A  A G+ P +GF H  +    +   D+ +  +  
Sbjct: 548 R----DAVNALLSLAYSILAKDCTSAAHAVGFDPYVGFYHQPRFGRPALALDLMEEFRPL 603

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                   +       P   VR A   +  S     +     E  + +    P
Sbjct: 604 VADSVVLTLINTRMISPTDFVR-AGDAVNLSPAGRKQFFNAYEQRMRSMITHP 655


>UniRef50_Q3B3C1 CRISPR-associated protein, Cas1 family n=20 Tax=Bacteria
           RepID=Q3B3C1_PELLD
          Length = 343

 Score =  195 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 45/311 (14%), Positives = 89/311 (28%), Gaps = 46/311 (14%)

Query: 11  LKDRVSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K  ++ +F+  Q   +       V+      +  +P+  +  I+       S   +   
Sbjct: 1   MKKLLNTLFVTTQGAYLSKEGECAVIKIDKVEKVRLPLHMLDGIICFGQITCSPFLMGHC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA 128
           A  G  + ++ E G  +     P          Q + A +      + R     + G   
Sbjct: 61  AANGVTVTFLTEYGKFLCQVQGPTKGNILLRRAQYRQADNYLQSAMLARSFVIGKIGNSR 120

Query: 129 P---------------------------------ARRSVEQLRGIEGSRVRATYALLAKQ 155
                                                  E++RGIEG   R  + +  + 
Sbjct: 121 VTLARALRDHPDKIDCEKMHYAQQLLAGCIKKLGNETDQERIRGIEGEAARIYFEVFDQC 180

Query: 156 YG-----VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG 210
                    +NGR   P      D +N  +S   + +     +A+ + G  PA GF+H  
Sbjct: 181 ITSSDPLFCFNGRNRRPP----VDRVNCLLSFLYTLVTHDIRSALESCGLDPAAGFLHKD 236

Query: 211 KPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
           +P   S   D+ +  +       A  +  R     +     A   +         L+   
Sbjct: 237 RPGRPSLALDMLEEFRSYIADRMALSLINRGQIHANDFTVSATGAVLMKDDARKTLLTAY 296

Query: 269 EDVLAAGEIQP 279
           +         P
Sbjct: 297 QKRKQDEIEHP 307


>UniRef50_C5BP90 CRISPR-associated protein Cas1 n=3 Tax=Gammaproteobacteria
           RepID=C5BP90_TERTT
          Length = 339

 Score =  195 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 53/309 (17%), Positives = 96/309 (31%), Gaps = 46/309 (14%)

Query: 11  LKDRVSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K   + +F+      +       V+  ++     IP+ ++  I       VS   +   
Sbjct: 1   MKKLQNSLFITRQKSYVHKQRETIVVEQESEKILQIPIHAIKSIFCFGNVIVSPFLLGFC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL------ 122
           A+ G  L +  E G   + +   G    + LL + +    +   L V R +         
Sbjct: 61  AENGVGLAFFTEYGR--FLARIQGPQSGNVLLRRIQYEKTKSAPLDVARAIIAAKIVSSR 118

Query: 123 ---------------------RFGEPAPARR---SVEQLRGIEGSRVRATYALLAKQ--- 155
                                R        R   S+++LRG EG      +++       
Sbjct: 119 SVLQRHIRNYGSQDDVVKVIGRLKHNLEQARVDPSLDRLRGTEGVAAANYFSVFQHLVRV 178

Query: 156 ---YGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKP 212
               G  +NGR   P      D IN  +S   S L     AA+   G  P +GF+HT + 
Sbjct: 179 ENDAGFAFNGRNKRPP----TDPINAMLSFLYSVLGNDISAALQGVGLDPQVGFLHTDRS 234

Query: 213 L--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
              S   D+ + ++   V         R   +     +     +  S      L+   ++
Sbjct: 235 GRDSLAMDLLEELRAWWVDRLVLTQVNRREIKARDFSQAVSGAVTMSESARKALLKAYQE 294

Query: 271 VLAAGEIQP 279
                   P
Sbjct: 295 KKHEEVEHP 303


>UniRef50_A4J500 CRISPR-associated protein Cas1 n=1 Tax=Desulfotomaculum reducens
           MI-1 RepID=A4J500_DESRM
          Length = 544

 Score =  195 bits (495), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 43/311 (13%), Positives = 92/311 (29%), Gaps = 42/311 (13%)

Query: 6   LNPIPLKDRVSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
           + P P  +   ++++  Q   +       ++         IP+ ++  ++L     +S  
Sbjct: 203 VRPQPGINLGRVLYVDEQGASLYKKGERVLVTKDQIKFKDIPLCNLDQVVLVGNVNLSSQ 262

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR 123
            ++L    GT + ++   G             S   + Q +    ++ RL    +    +
Sbjct: 263 LIKLFLGRGTEVHFISTKGKYYGCLQAALSKNSVLRIAQHRAYQKQEERLLYASEFVRGK 322

Query: 124 FGEP-----------------------------APARRSVEQLRGIEGSRVRATYALLA- 153
                                                + + +L G+EG+  R  +++   
Sbjct: 323 LSNMRTNLLRYNRSLNNHSIDEAVSRIKNIIKRLEKAKDLNELMGLEGAGSRDYFSVFGL 382

Query: 154 ---KQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG 210
               +    +N R   P      D  N  +S + S L      A+   G+ P IGF+H  
Sbjct: 383 LIKDRVPFDFNKRSRRPP----EDPANALLSFSYSLLLKDVITAVQVVGFDPFIGFLHRS 438

Query: 211 K--PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
                +   DI +  +             +     + +        F S     K+  L 
Sbjct: 439 DFGRPALALDIIEEFRPVVADSVVLTALNKGVIA-EGDFEYRMGGCFLSETGRKKMYRLY 497

Query: 269 EDVLAAGEIQP 279
           E+        P
Sbjct: 498 EERRKEMITHP 508


>UniRef50_A2SRR7 CRISPR-associated protein, Cas1 family n=24 Tax=cellular organisms
           RepID=A2SRR7_METLZ
          Length = 344

 Score =  194 bits (494), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 36/311 (11%), Positives = 90/311 (28%), Gaps = 47/311 (15%)

Query: 11  LKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           ++   +++++      +     + V+  +      +P+ ++  ++       S   + L 
Sbjct: 1   MRKLRNVLYVTNPKSYLSRDGESIVVSVENQELARVPIRNLEGVVCFGYMGASPGMMALC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR----------K 118
            +    + +V   G  +   G            Q  ++ DE+   K+            +
Sbjct: 61  TENDVGMCFVSPYGKFMARIGGNVSGNVLLRKRQYAVSDDEEASKKIAAYCILGKLMNCR 120

Query: 119 MFELRFGEPAPARRSVE------------------------QLRGIEGSRVRATYALLAK 154
               RF    P   S E                        +LRG EG   +  +     
Sbjct: 121 TVLQRFSRDYPDMVSREFEQNFKRLSEGILQIRAGTCGSLNELRGFEGILSKYYFHSFND 180

Query: 155 QY-----GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
                    ++  R   P      D +N  +S + + +     +A+ + G  P +GF+H 
Sbjct: 181 LILSTEPEFSFENRSRRPP----LDRVNALLSFSYTLIAADCASALESVGLDPQVGFLHR 236

Query: 210 GKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPL 267
            +P   S   D+ +  +          +      + D         +  +      ++  
Sbjct: 237 VRPGRPSLALDLMEEFRPYLGDRFVLSLINNRVVKADDFAVKENGAVLLTDDARKTVLQA 296

Query: 268 IEDVLAAGEIQ 278
            +       + 
Sbjct: 297 WQKRKKEEVMH 307


>UniRef50_C7G6C1 CRISPR-associated protein Cas1 n=3 Tax=Firmicutes
           RepID=C7G6C1_9FIRM
          Length = 334

 Score =  194 bits (494), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 46/319 (14%), Positives = 101/319 (31%), Gaps = 40/319 (12%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +++  Q   I +    F +  K G+   IP  ++  I +    +++   +    + G
Sbjct: 1   MSYLYVSEQGASIGIEANRFQVNYKDGMIKSIPAETLEMIEVFGSVQITTRCLTECLKRG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP--- 129
             +++   +G               +   QA++  +E  +L++ +++ + +         
Sbjct: 61  VNILFYSTSGAYYGRLISTSHVNVQRQRIQAEIGHNETFKLEMSKRIIDAKIRNQVVVLR 120

Query: 130 -------------------------ARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNG 162
                                      +SVEQ+ G EG+  +  + +L K       + G
Sbjct: 121 RYARGRDEDIHRMIIEMQNMQKKLLYAKSVEQVMGYEGTAAKIYFKVLGKLIDEQFVFEG 180

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIA 220
           R   P      D  N  IS   S +       I   G  P  G +H  +    +   D+ 
Sbjct: 181 RSRRPP----MDPFNSLISLGYSIILNELYGKIEGKGLNPYFGVMHKDREKHPTLASDLM 236

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDRE-VRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
           +  +   +   A  +   +    +     +    +F       K I  +E          
Sbjct: 237 EEWRAVLIDTTALSMLNGHELVKEDFYTGIDQPGVFLEKDGFRKYIQKLEGKFRTENRYL 296

Query: 280 PAPPED-AQPVAIPLPVSL 297
                  +   A+ L V+ 
Sbjct: 297 SYIDYSVSFRRAMDLQVNQ 315


>UniRef50_C4FMU2 Putative uncharacterized protein n=1 Tax=Veillonella dispar ATCC
           17748 RepID=C4FMU2_9FIRM
          Length = 331

 Score =  193 bits (491), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 41/298 (13%), Positives = 91/298 (30%), Gaps = 41/298 (13%)

Query: 15  VSMIFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +++      I    G  V+     +   +P+  +  I +     ++ + V    + G
Sbjct: 1   MSSLYVTEAGSFIKRDGGHVVVGRNNEVLFEVPLERIEDITVFDSVSITSSLVTDFIERG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------L 122
             + W+   G              +K   Q  L  D   R+ + RK+             
Sbjct: 61  VPITWLSGYGKYFGTLINTNTIDINKHKKQFDLLDDNAFRVAMSRKIIRAKVRNQLTILR 120

Query: 123 RFGEPAPARRSVE--------------------QLRGIEGSRVRATYALLAKQYG--VTW 160
           R+        +++                    +L G EG   R  +  L K       +
Sbjct: 121 RYARNLEEDINIDAQIANIKSVRSHIGECMRVSELMGYEGLISRLYFEALGKIVPSAFAF 180

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYD 218
             R   P      D  N  +    S L+    A ++ AG  P +G +H+      +   D
Sbjct: 181 TKRTKQPPR----DPFNAMLGLGYSMLFNEILAGVINAGLHPFVGIMHSLAKGHPALASD 236

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGE 276
           + +  +   +      +  RN  +   E   + +  + +++     +      + +  
Sbjct: 237 LIEEWRAPIIDSMVLSMVSRNMVDL-AEFDNSDKGCYLTAEGRKVFLTAYNKKIRSEN 293


>UniRef50_Q3J7J6 CRISPR-associated protein, Cas1 family n=2 Tax=Nitrosococcus oceani
           RepID=Q3J7J6_NITOC
          Length = 295

 Score =  193 bits (491), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 71/295 (24%), Positives = 114/295 (38%), Gaps = 35/295 (11%)

Query: 8   PIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTG---IRTHIPVGSVACIMLEPGTRVSHAA 64
           PI    R  + +L++ ++   D   V   + G       IP  +   I+L  GT ++ AA
Sbjct: 2   PILPSHRQGLYYLEHCRVMAKDERVVYACQEGAFTKFFAIPPANTNVILLGSGTSLTQAA 61

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR- 123
            RL A    ++ +VG  G  ++ + Q     ++      +L  D D RLKV +     R 
Sbjct: 62  ARLLASEQVMVAFVGGGGSPLFLASQNEYRPTEYCQAWMRLWQDNDQRLKVAKTFQRNRA 121

Query: 124 ---------FGEPAPARRSVEQL-----------------RGIEGSRVRATYALLAKQYG 157
                      EP P + S+E+L                    E    +  Y   A    
Sbjct: 122 EFLMQQWPKLAEPKPHKASLEKLAERYLADIELAGDNGTILAQEAKFAKKLYKFWANCTE 181

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH-TGKPLSFV 216
                   DP   +  D  N  +      +YG+  A +   G   ++  +H T +  + V
Sbjct: 182 T--ENFTRDPGKRDFNDPFNSYLDHGNYLVYGIAAAVLWVLGIPHSLPVIHGTTRRGALV 239

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDV 271
           +D+ADIIK   V+P AF+ A    G  D+E+R AC      S  +  L   I+ V
Sbjct: 240 FDVADIIKDTCVMPIAFQHAA--AGRSDQEMRQACIAWLDESHAMTFLFQSIKRV 292


>UniRef50_B2RM83 CRISPR-associated protein Cas1 n=3 Tax=Bacteroidetes
           RepID=B2RM83_PORG3
          Length = 338

 Score =  192 bits (489), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 47/307 (15%), Positives = 87/307 (28%), Gaps = 49/307 (15%)

Query: 14  RVSMIFLQYGQIDVIDGAFVL---------IDKTGIRTHIPVGSVACIMLEPGTRVSHAA 64
           + +      G++   D               ++ G   +IPV  ++   +    R + + 
Sbjct: 2   KKTYYLFNPGELSRKDNTIRFVPIQEGENGQEQAGQARYIPVEGISDFYVFGSLRANSSL 61

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGG---ARSDKLLYQAKLALDEDLRLKVVRKM-- 119
                     + +        Y               LL QA    ++  RL + RK   
Sbjct: 62  YNFLGSNDIAVHFFDYY--ENYTGSFMPRDFLLSGKMLLAQASAYKNKKKRLFLARKFIE 119

Query: 120 ------------FELRFGEP-------------APARRSVEQLRGIEGSRVRATYALLAK 154
                       +  R  +                   ++E L GIEG+  +A Y     
Sbjct: 120 GAASNMQKNLAYYNNRGKDMQPMMELIDKYSLRLEETTTIEALMGIEGNIRQAYYDAFNL 179

Query: 155 QY-GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--K 211
                    R   P   E    +N  IS      Y +   AI  +   P I F+HT   +
Sbjct: 180 IIDPFEMGARSKQPPQNE----VNALISFGNMMCYTLCLKAIHQSQLNPTISFLHTPGER 235

Query: 212 PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDV 271
             S   DI+++ K   V    F++  +   +  +           +       +   E+ 
Sbjct: 236 RYSLCLDISEVFKPILVDRTIFKVMNKRIIQA-KHFDKQLNKCILNPSGKKLFVQAFEER 294

Query: 272 LAAGEIQ 278
           L+     
Sbjct: 295 LSETIRH 301


>UniRef50_Q1Q3I6 Putative uncharacterized protein n=1 Tax=Candidatus Kuenenia
           stuttgartiensis RepID=Q1Q3I6_9BACT
          Length = 328

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 34/294 (11%), Positives = 85/294 (28%), Gaps = 38/294 (12%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGE 80
           Q   +       ++     +   +    +  +++    + +  AV    + G  +  +  
Sbjct: 4   QNSILRKSGDRLIIEKDDKVLLEVQCHKIDAVLIFGNVQFTTQAVHELFEHGIEMAILTR 63

Query: 81  AGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG--------------- 125
            G  +     P        + Q K   ++D RL   + +   +                 
Sbjct: 64  TGKLIGQITSPYTKNITLRVQQFKQYWNDDFRLAFAKVIVCGKIQNCIQLVRSFSYNHPR 123

Query: 126 --------------EPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWNGRRYDPKD 169
                             +  ++ QL GIEG+  R  +    K       + GR+  P  
Sbjct: 124 NSFDVEMDDLSLRLNEVESAANISQLFGIEGNAARVYFTSFGKMILSAFAFPGRKKYP-- 181

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFDT 227
               D +N  +S   + ++    + +   G+ P +G+ H       S   D+ +  +   
Sbjct: 182 --STDPVNALLSLNYTMIFNEISSLLDGLGFDPYLGYYHGIDYGRSSLASDLMEEFRAPI 239

Query: 228 VVPKAFEIARRNPGEPDRE-VRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
                  +        +      +   ++   + L +     E ++    + P 
Sbjct: 240 ADRITLNLINNRIFCEEDFYANPSTGGVYLKREPLKRYFVEYETMINREFLHPQ 293


>UniRef50_UPI000197AF65 hypothetical protein BACCOPRO_02409 n=1 Tax=Bacteroides coprophilus
           DSM 18228 RepID=UPI000197AF65
          Length = 340

 Score =  192 bits (488), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 48/308 (15%), Positives = 93/308 (30%), Gaps = 43/308 (13%)

Query: 11  LKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           ++  ++ +++      I       V+         IP  ++  I+       S   ++L 
Sbjct: 1   MRKLLNTLYVTTPNAYISKDGLNIVVSVNQEEVFRIPAINIESIVTFGYMGASPGVMKLC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE-- 126
           +  G  L ++   G  +                Q +L  DE   L V   M   +     
Sbjct: 61  SDSGISLTFLSPHGKFISRVQSATKGNVLLRKKQYQLVDDEAWSLHVSLLMIGGKIQNYR 120

Query: 127 ---------------PAPARRSVE-------------QLRGIEGSRVRATYALLA----- 153
                             A +++E              L G EG    A + +L      
Sbjct: 121 NILRRYIRDYGENENVNQAIQTLERAKRNALQAPDKTTLIGYEGLASNAYFEVLPVLILN 180

Query: 154 KQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL 213
           ++    + GR   P      D +N  +S A + +     AA+   G  P +GF+HT +P 
Sbjct: 181 QKADFPFQGRNRRPPK----DAVNAMLSFAYTLIANDVAAALETIGLDPYVGFLHTLRPG 236

Query: 214 --SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDV 271
             S   D+ + ++          +  +        +      +  S K     I   ++ 
Sbjct: 237 RTSLALDMMEELRAYLGDRFVLSLINKRQISSKEFLYQGDNGVVMSDKGKKIFISAWQNR 296

Query: 272 LAAGEIQP 279
                I P
Sbjct: 297 KRETIIHP 304


>UniRef50_C1XN81 CRISPR-associated protein Cas1 n=2 Tax=Meiothermus
           RepID=C1XN81_MEIRU
          Length = 323

 Score =  192 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 53/300 (17%), Positives = 99/300 (33%), Gaps = 36/300 (12%)

Query: 18  IFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVW 77
           +  Q   + +  G   +         +P   V  +++    R++  A+    + G  +++
Sbjct: 5   LTEQSSTLRLSQGRLRVELDEQTLAELPARKVRGVVVWGNVRLTTPALAFLLRQGVPVLY 64

Query: 78  VGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR----------KMFELRFG-- 125
               G     +  P     + L  Q     +    L + +          +M   R    
Sbjct: 65  ATLEGQLYGQAQAPQSLAPEVLRAQLLAQQNP---LPLAQGFLLGKLRSGQMLLERLARQ 121

Query: 126 --------------EPAPARRSVEQLRGIEGSRVRATYALL-AKQYGVTWNGRRYDPKDW 170
                         E  P  RS+E LRGIEG+  RA +A L A      ++GR   P   
Sbjct: 122 APITPQQAEIEAALEALPQARSLEALRGIEGNAARAYFAGLQAVLAPYGFSGRNRRPP-- 179

Query: 171 EKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTV 228
              D +N  +S     L G    A+  AG  P +G +HT      +  +D+ +  +   V
Sbjct: 180 --TDAVNAALSYGYMVLLGRVLLALGIAGLHPELGLLHTEGRRVPALAFDLMEEFRVSVV 237

Query: 229 VPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQP 288
                    R+   P +        ++ +      L+  +E+  +     P    +  Q 
Sbjct: 238 DAVVIAAFLRSELTPQQHSEARNGGVYLNEAGRKALLRRLEERFSQEAQHPKGFRKPYQE 297


>UniRef50_B4W4R1 CRISPR-associated protein Cas1 n=1 Tax=Microcoleus chthonoplastes
           PCC 7420 RepID=B4W4R1_9CYAN
          Length = 354

 Score =  191 bits (486), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 41/305 (13%), Positives = 101/305 (33%), Gaps = 40/305 (13%)

Query: 11  LKDRVSMIFLQYGQ-IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAA 69
            ++  ++  ++ G  I      F++      +  +P+  V  I++    ++S   +++  
Sbjct: 18  HREMAAIYLIEQGTTIYKEYQRFIIYVSEKPKLEVPIREVQQILVFGNIQLSTPVMQVCL 77

Query: 70  QVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF--------- 120
           +    +V++ ++G              D+ L Q +   D   + +V + +          
Sbjct: 78  REQIAVVFLSQSGRYHGHLWSSEFRDLDQELVQVRRWGDAAFQFQVSQAIVYGKLMNSKQ 137

Query: 121 -------ELRFG-------------EPAPARRSVEQLRGIEGSRVRATYALLAKQY---G 157
                  + +               E      S+++LRG EG      +  L +      
Sbjct: 138 LLLRFNRKRKLPDVERAIIGINQDIEALEFSESLDRLRGYEGIGAARYFPALGQLITNSR 197

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--F 215
             ++ R   P      D +N  +S   + L+      I+A G +P +G  H G+      
Sbjct: 198 FEFSLRNRQPP----TDPVNSLLSFGYTLLFNNVLGFIIAEGLSPYLGNFHYGERQKPYL 253

Query: 216 VYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLAC-RDIFRSSKTLAKLIPLIEDVLAA 274
            +D+ + ++   V      I   +  +P     +     ++ +       +   E  +  
Sbjct: 254 AFDLMEEMRSVVVDSLVLNIVNHSLFKPQDFDTVPSTGGVYLNQSARRVFLKQFETRMNE 313

Query: 275 GEIQP 279
               P
Sbjct: 314 EVSHP 318


>UniRef50_Q8F1F5 Putative uncharacterized protein n=2 Tax=Leptospira interrogans
           RepID=Q8F1F5_LEPIN
          Length = 550

 Score =  191 bits (485), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 56/322 (17%), Positives = 99/322 (30%), Gaps = 51/322 (15%)

Query: 3   WLPLNPIPLKDRVSMIFL--QYGQIDVIDGAFVLID-----KTGIRTHIPVGSVACIMLE 55
           + P+   P K   + + +     +I   D   ++       +      IP+  +  + + 
Sbjct: 199 YEPIRLFPEKREKTTLHVFGHDSRIKKSDNVLLVEKVTETGEKSKSEKIPIQEIESVNIH 258

Query: 56  PGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKV 115
              ++S   ++        + W    G  +            + + Q K    E +RL +
Sbjct: 259 GNCQISSQMIKFLVSEEIPVHWFSGGGNYIGGININPSG-VQRRIRQFKALTKETIRLNL 317

Query: 116 VRKMFELRFGEP-------------------------------APARRSVEQLRGIEGSR 144
            +K+   +                                     +  S  QL GIEGS 
Sbjct: 318 AKKLVSAKCESQLRYLLRATRGKDETRNETESYLATIRSGLKNIESADSPSQLLGIEGSS 377

Query: 145 VRATYALLAKQYG-----VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAG 199
            RA ++ L          +  NGR   P      D  N  +S   S LY     AI+A G
Sbjct: 378 ARAYFSGLPALLKNSDPFLVPNGRSKRPPK----DPFNATLSFLYSLLYKSVRQAIIAVG 433

Query: 200 YAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRS 257
             P+ GF HT +  +   V D+ ++ +             R     D +  +    ++ S
Sbjct: 434 LDPSFGFYHTPRSSAEPLVLDLMELFRVSLCDMTLIGSINRKSW-IDEDFEITKNKVWLS 492

Query: 258 SKTLAKLIPLIEDVLAAGEIQP 279
                K   L E  L      P
Sbjct: 493 ESGRKKATQLYETRLDDTWKHP 514


>UniRef50_B9LWK7 CRISPR-associated protein Cas1 n=4 Tax=Halobacteriaceae
           RepID=B9LWK7_HALLT
          Length = 331

 Score =  191 bits (485), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 54/314 (17%), Positives = 94/314 (29%), Gaps = 41/314 (13%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +      G++   +    +    G   H+PV S+  + L      +  A+ L    G   
Sbjct: 5   NHHVFTDGELSRSEDTLRIDTLDGEVEHLPVESIDTLYLHGQIDFNTRALGLLNDHGVPA 64

Query: 76  VWVGEAGVRVYASGQPGGA---RSDKLLYQAKLALDEDLRLKVVRKMFELRFGE------ 126
              G      Y             + ++ Q +   D D RL +   M E           
Sbjct: 65  HVFGWKD--YYKGSYLPKRSHLSGNTVVEQVRAYDDPDRRLGIATLMIEASIHNMRANLV 122

Query: 127 ---------------------PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW--NGR 163
                                 A    S++ LRG E +  +  Y+  ++     +  + R
Sbjct: 123 YYNARDCSFDSEIDRLESLKTKASTAESIDGLRGTEATARKTYYSCFSEILRDPFALDRR 182

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIAD 221
            Y+P      +  N  IS   + +Y    +AI      P +GF+H    +  +   DIAD
Sbjct: 183 EYNPP----TNETNALISFLNAMVYTACVSAIRKTALDPTVGFMHEPGDRRFTLSLDIAD 238

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPA 281
           I K        F +  R    PD E          +      ++   E+ L      P  
Sbjct: 239 IYKPILADRVLFRLVNRRQISPD-EFESDLDGCLLTEDGRLTVLAEYEETLDKTVEHPRL 297

Query: 282 PPEDAQPVAIPLPV 295
               +    +   V
Sbjct: 298 KRNVSYKTLVQTDV 311


>UniRef50_D0KYZ2 CRISPR-associated protein Cas1 n=3 Tax=Bacteria RepID=D0KYZ2_HALNC
          Length = 344

 Score =  190 bits (482), Expect = 6e-47,   Method: Composition-based stats.
 Identities = 46/311 (14%), Positives = 91/311 (29%), Gaps = 45/311 (14%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            I      + + +    +  +   +  +P+  +  ++      +S A +   A  G  LV
Sbjct: 9   YIMTPNAYVHLENATVRIDVEREKKLQVPLHHLNGLVCFGNIMISPALMHRLADDGKSLV 68

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE---------- 126
            +  +G        P            + A D    L++ R +   +             
Sbjct: 69  LMDSSGRFKARLEGPVSGNILLRQAHHRQASDAAFALEIARTIVSGKLKNSRSVVQRGAR 128

Query: 127 -----------------------PAPARRSVEQLRGIEGSRVRATYALL------AKQYG 157
                                   A A  S+++LRGIEG   R  ++ +      A +  
Sbjct: 129 ETSDTIETTQLTRSADNLAASLRAAAAATSMDELRGIEGEAARGYFSAINLIVKTAMRAN 188

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SF 215
              NGR   P      D  N  IS   + L     +AI A G    +GF+H  +P   + 
Sbjct: 189 FQLNGRTRRPP----LDRFNALISFLYAMLMNDCRSAIEATGLDAQLGFLHAVRPGRAAL 244

Query: 216 VYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
             D+ +  +       A  +  R               +  + +    ++   ++     
Sbjct: 245 ALDLMEEFRAIAADRLALTLINRGQINASDFDEREGGAVMLNDRGRRAVVTAWQERKQEI 304

Query: 276 EIQPPAPPEDA 286
              P    +  
Sbjct: 305 VTHPLTETKIP 315


>UniRef50_O66692 Putative uncharacterized protein n=2 Tax=Aquificaceae
           RepID=O66692_AQUAE
          Length = 316

 Score =  189 bits (481), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 44/296 (14%), Positives = 87/296 (29%), Gaps = 24/296 (8%)

Query: 17  MIFL-QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           + ++  +G +   +      +   ++  IPV  V  I +     ++   +   A  G  L
Sbjct: 4   VYYINSHGTLSRHENTLRFENA-EVKKDIPVEDVEEIFVFAELSLNTKLLNFLASKGIPL 62

Query: 76  VWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKM---------FELRFG 125
            +    G        +        L+ Q +  LD   RL + +           +  +  
Sbjct: 63  HFFNYYGYYTGTFYPRESSVSGHLLIKQVEHYLDAQKRLYLAKSFVIGSILNLEYVYKIS 122

Query: 126 -----EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCI 180
                       S+ +L  +E    +  Y  L +  G     R   P      + +N  I
Sbjct: 123 ADTYLNKVKETNSIPELMSVEAEFRKLCYKKLEEVTGWELEKRTKRPPQ----NPLNALI 178

Query: 181 SAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARR 238
           S   S  Y      I      P + ++H    K  S   D+A++ K   V      + + 
Sbjct: 179 SFGNSLTYAKVLGEIYKTQLNPTVSYLHEPSTKRFSLSLDVAEVFKPIFVDNLIIRLIQE 238

Query: 239 NPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLP 294
           N  +            F +       +    ++L      P    + +    I L 
Sbjct: 239 NKIDKT-HFSTELNMTFLNEIGRKVFLKAFNELLETTIFYPKLNRKVSHRTLIKLE 293


>UniRef50_B8DWG2 CRISPR-associated protein Cas1 n=4 Tax=Bifidobacterium animalis
           subsp. lactis RepID=B8DWG2_BIFA0
          Length = 535

 Score =  189 bits (481), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 39/301 (12%), Positives = 82/301 (27%), Gaps = 38/301 (12%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
            +  +  G   +       T +P+ S+  + +     VS   +R        ++W    G
Sbjct: 219 ARAYLKSGRMHVSKNGDEITSVPLDSIQALQIHGNVDVSSGLMRELMWRNIPILWCSGTG 278

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA-------------- 128
             +  S    G   +  + Q       + RL + R+    +                   
Sbjct: 279 RLMGWSVSSYGPNGETRVAQ--HVASHEGRLDLAREFISAKIHNQIVLLRRSDKNNNVLF 336

Query: 129 ---------PARRSVEQLRGIEGSRVRATYALLAKQYGV------TWNGRRYDPKDWEKG 173
                         ++ +  +EG      ++       V       W  R   P      
Sbjct: 337 DMKHIEKSVVNANRIQDILSLEGQAAALYFSQFHHLISVNKRNEWPWLERMRHP----AP 392

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPK 231
           D +N  +    S L      AI++ G     GF+H+ K    +   D+ +  +       
Sbjct: 393 DPLNALLDYTYSLLLSDCIRAIVSCGLDAHAGFLHSSKRNKPALALDLMEEFRAPIADSV 452

Query: 232 AFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAI 291
              +      + +    +    +    +T   LI   E  +A     P      +    +
Sbjct: 453 VQTVVNNGEIKRNGFANV-MGSVRLRDETRKTLIGAYERRMATELKHPVYAYRASWRRIV 511

Query: 292 P 292
            
Sbjct: 512 E 512


>UniRef50_Q2NH78 Putative uncharacterized protein n=1 Tax=Methanosphaera stadtmanae
           DSM 3091 RepID=Q2NH78_METST
          Length = 332

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 48/308 (15%), Positives = 100/308 (32%), Gaps = 40/308 (12%)

Query: 18  IFL-QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
           +++   G +   +          + T IP+ ++  I       +   A+ L  +   ++ 
Sbjct: 13  LYINSNGILYRKENTLKF-KNKEVDTSIPIHAINEINCYGKVSLRSGAISLLQKEKIIIN 71

Query: 77  WVGEAGVRVYASGQPG---GARSDKLLYQAKLALDEDLRLKVVRKM-------------- 119
           +  + G   Y               ++ QA    +E+ R  + ++M              
Sbjct: 72  FFNKYG--YYEGSLYPKIALNSGVIVVKQALTYNNENKRCFIAKEMVNGMKHNMIKTLKY 129

Query: 120 FELRFGEPAPARRSVEQ----------LRGIEGSRVRATYALLAKQYG-VTWNGRRYDPK 168
           ++ +  +     +++E           +   EG   ++ Y              R + P 
Sbjct: 130 YKKKGKDVDEHIQNLENESILDGNINRILSSEGKLWQSYYPSFDNITKKFPIEKREFKPP 189

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFD 226
             E    +N  IS   S LY  T + I      P+I F+H  +    S   D+ADI K  
Sbjct: 190 KNE----MNSLISYGNSLLYTTTLSEIYHTYLHPSISFLHEPRERRFSLACDLADIFKPL 245

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDA 286
            +    F++   N    ++  +     ++ + K   K I    + L      P    + +
Sbjct: 246 IISRTIFKLVNTNIIN-EKHFKKDV-GVYLNEKGRQKFIQEYNNKLKTTIKHPQIKKKVS 303

Query: 287 QPVAIPLP 294
               I L 
Sbjct: 304 YRYLIRLE 311


>UniRef50_B0JKW9 CRISPR-associated protein Cas1 n=6 Tax=Cyanobacteria
           RepID=B0JKW9_MICAN
          Length = 334

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 43/324 (13%), Positives = 91/324 (28%), Gaps = 45/324 (13%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +  +++      +   D    +         +P+ +V  +++     VS A V    +  
Sbjct: 1   MGTVYVTREDAFLGKNDERLTVKASKETILDVPLLNVEGVVIFGRGSVSPALVIELLERH 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE------ 126
             L +V   G  +                Q + A D    + +VR     +         
Sbjct: 61  IPLSFVTATGKYLGRLEPEMTKNIFVRRAQWQAAGDSPKAIHLVRGFVRGKLKNYRNILL 120

Query: 127 -----------------------PAPARRSVEQLRGIEGSRVRATYALLAKQY---GVTW 160
                                        +++ LRG+EG+   A ++           T+
Sbjct: 121 RRQRDRKELDLQTAIACLEAAIGSIETTSAIDSLRGLEGAGSAAYFSCFDSLILGDTFTF 180

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYD 218
             R   P      D +N  +S   + L    ++AI   G+ P +G++H  +    S   D
Sbjct: 181 ASRNRRPPR----DPVNSLLSLGYALLRHDVQSAINLVGFDPYLGYLHYQRYGRPSLALD 236

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIF-RSSKTLAKLIPLIED----VLA 273
           + +  +   V              P+             + + L   + L E        
Sbjct: 237 LMEEFRAIVVDAVVLNGVNHPYLTPEHFTTEPLSGAVSLTREGLQIFLRLYEQKKQSKFK 296

Query: 274 AGEIQPPAPPEDAQPVAIPLPVSL 297
              +      ++A  +   L    
Sbjct: 297 HPVMGKQCTYQEAFEIQARLMAKY 320


>UniRef50_Q2FQQ2 CRISPR-associated protein Cas1 n=2 Tax=Methanomicrobia
           RepID=Q2FQQ2_METHJ
          Length = 347

 Score =  189 bits (479), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 44/301 (14%), Positives = 93/301 (30%), Gaps = 28/301 (9%)

Query: 10  PLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRT-HIPVGSVACIMLEPGTRVSHAAVRLA 68
            L+D    I   YG+I +  G   + D  G      P+  V  + +     VS   ++  
Sbjct: 25  LLEDDTIYITTPYGKISLDGGRIQVKDSDGEIVASFPLEKVCTMNVFGSASVSTPLLKHC 84

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA 128
           +    ++ +    G   Y         +  L+ + +  + ++  L + R++   +     
Sbjct: 85  SDKEVVINYFTNFGK--YFGSFVPSRNTIALVRRHQAGITKEKSLAICREIIHAKLQNSC 142

Query: 129 P---------------------ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDP 167
                                    SV+ LRGIEG      + +L+      W  R    
Sbjct: 143 VFLARKRVEVPSLLKELRDRSLHAVSVDSLRGIEGEAASIYFPMLSSSLPDEW--RSDKR 200

Query: 168 KDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKF 225
                 D +N  +S   + +     +A+      P IG +H  +    +   D+ +  + 
Sbjct: 201 TRRPPRDELNALLSLTYTMVNTEVISALRQYNLDPFIGVMHVDRHGKPALALDLLEEFRP 260

Query: 226 DTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPED 285
                    +  +     D   + +  +     K L      +E+ L     +     + 
Sbjct: 261 VFCDAFVARLINKRMITKDDFTQGSRLNDTAFKKYLGFYHDFMEESLKHPRFKYSVSRKK 320

Query: 286 A 286
           A
Sbjct: 321 A 321


>UniRef50_B7KM77 CRISPR-associated protein Cas1 n=1 Tax=Cyanothece sp. PCC 7424
           RepID=B7KM77_CYAP7
          Length = 334

 Score =  189 bits (479), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 39/302 (12%), Positives = 99/302 (32%), Gaps = 41/302 (13%)

Query: 15  VSMIFL-QYGQ-IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           ++ ++L + G  +       ++      +  + +  V  IM+    ++S  A+    +  
Sbjct: 1   MATLYLMEQGTWVQKEQERLIIQVSKTQKMEVLMREVERIMIFGNVQLSTPAINACLKHN 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE----------L 122
            L++++ +AG         G    +  + Q K   + + ++K+ + +            +
Sbjct: 61  ILVLFLNQAGQYNGHLWSLGSIHLNNEMVQIKRHQEHEFQVKISKAIVYGKLMNSKRLLM 120

Query: 123 RFGEP-------------------APARRSVEQLRGIEGSRVRATYALLAKQY---GVTW 160
           R                         +  +++QLRG EG      +    +       ++
Sbjct: 121 RLNRKRQVPDMDKVIEGINSDILSLESVDNLDQLRGYEGIAAARYFPAFGQLITNAAFSF 180

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYD 218
           + R   P      D +N  +S   + L+    + I++ G +P  G  H G+       +D
Sbjct: 181 SLRNRQPP----TDPVNSLLSFGYTLLFNNVLSLIISEGLSPYFGNFHYGERDKPYLAFD 236

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACR-DIFRSSKTLAKLIPLIEDVLAAGEI 277
           + +  +   V      +             +A    ++ + K     +   E  +     
Sbjct: 237 LMEEFRAIIVDGMVLRVINNGLLTLKDFEPVASNGGVYLTDKGRRIFLKEFESRINKLIS 296

Query: 278 QP 279
            P
Sbjct: 297 HP 298


>UniRef50_Q8YWX6 Alr1468 protein n=4 Tax=Cyanobacteria RepID=Q8YWX6_ANASP
          Length = 668

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 45/301 (14%), Positives = 98/301 (32%), Gaps = 40/301 (13%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           ++ +++  Q   + V +  F +  +  +R  +PV  V+ ++L     VSH AV +A +  
Sbjct: 335 MTTLYITDQGAYLSVKNQQFQVFHQGELRIKVPVMRVSNVVLFGCCNVSHGAVSMALRRR 394

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG------- 125
             ++++ + G         G A+ + L+ Q +   + +   K    +   +         
Sbjct: 395 IPIMYLSQKGRYFGRLQTEGDAKVEYLMLQVERCQNHEFTRKQAEAIVRAKLHNSRALLL 454

Query: 126 ----------------------EPAPARRSVEQLRGIEGSRVRATYALLAKQY--GVTWN 161
                                 E      S++ LRG EG      +  L   +     + 
Sbjct: 455 KLNRRHPSKIAATAISGIAELMEKLSLAESMDSLRGYEGKAATLYFQGLGSLFTGAFVFE 514

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDI 219
            R   P      D +N  +S   + L     + +   G     G +H  +    + V D+
Sbjct: 515 KRTKRPP----TDPVNSLLSLGYTLLSQNVFSFVQVIGLHTHFGNLHVPRDNHPALVSDL 570

Query: 220 ADIIKFDTVVPKAFEIARRNPGEPDREVRLACR-DIFRSSKTLAKLIPLIEDVLAAGEIQ 278
            +  +   V      +        +       +  ++     L K +   E+ L +    
Sbjct: 571 MEEFRAQLVDSLVAYLINSKIFTFEDFTPPDEKGGVYLQPHALKKFLKHWEEKLQSEVTH 630

Query: 279 P 279
           P
Sbjct: 631 P 631


>UniRef50_B7GYY4 CRISPR-associated protein Cas1 n=8 Tax=Proteobacteria
           RepID=B7GYY4_ACIB3
          Length = 321

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 57/308 (18%), Positives = 114/308 (37%), Gaps = 51/308 (16%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDK---TGIRTHIPVGSVACIMLEPGTRVS 61
            L  I    R ++ +L++ ++   DG  + + +        +IP+ +   I+L  GT ++
Sbjct: 8   DLKAILHSKRANLYYLEHCRVMQKDGRVLYLTEAKNENQYWNIPIANTTVILLGTGTSIT 67

Query: 62  HAAVRLAAQVGTLLVWVGEAGVRVYAS-------GQPGGARSDKLLYQAKLALDEDLRLK 114
            AA+R+    G L+ + G  G  ++A         Q     ++ +        DE  RL 
Sbjct: 68  QAAMRMLCSAGVLVGFCGGGGTPLFAGSEVEWLTPQSEYRPTEYMQGWMSFWFDETKRLD 127

Query: 115 VVRKMFELR--------------------------------FGEPAPARRSVEQLRGIEG 142
           V +     R                                F +  P    V  L   E 
Sbjct: 128 VAKAFQFARIEFIRKIWAKDKDLKDEGFYLDNLDIQQALNGFEKKIPNMTKVGDLLLAEA 187

Query: 143 SRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAP 202
              +  Y + A +  +++       ++ E+GD  N  ++      YG++   +   G + 
Sbjct: 188 QTTKQLYKIAATRCKLSFE------RNPEQGDLANDFLNHGNYLAYGLSATTLWVLGISH 241

Query: 203 AIGFVH-TGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTL 261
           +   +H   +  + V+D+AD+IK   V+P AF  A+      ++E R      F   + L
Sbjct: 242 SFAVMHGKTRRGALVFDVADLIKDAVVLPWAFICAKEGAT--EQEFRQQLLQKFTDYRCL 299

Query: 262 AKLIPLIE 269
             +   ++
Sbjct: 300 DWMFDQVK 307


>UniRef50_Q1J1U7 CRISPR-associated protein Cas1 n=1 Tax=Deinococcus geothermalis DSM
           11300 RepID=Q1J1U7_DEIGD
          Length = 342

 Score =  187 bits (476), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 39/316 (12%), Positives = 97/316 (30%), Gaps = 43/316 (13%)

Query: 11  LKDRVSMIFLQ--YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           ++  ++ +++Q     + +      +  +   +  +P+  +  +++     +S   +   
Sbjct: 1   MRQLLNTLYIQTQGTYLHLDTDNIRVEVERTKKAMLPLHHIEGVVVFGNVLLSPFLIHRL 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP- 127
           A+    + W+ E G  +  +  P          Q   A +    L + R +   +     
Sbjct: 61  AREHKPVTWLSEHGRFMARTETPMSGNVLLRTAQHACAGNAARTLAIARLIAAGKLQNQK 120

Query: 128 -------------------------------APARRSVEQLRGIEGSRVRATYALLAKQY 156
                                           P   +V+++RG EG+  R  + +     
Sbjct: 121 VTLLRAAREAEADDAALLRQAARDINVQIACLPLTETVDEVRGTEGTAARLYWEVFPLML 180

Query: 157 G----VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKP 212
                  W   R+        D IN  ++   + L     +A  A G  P +GF+H  +P
Sbjct: 181 RQNRDFFWLSERHRRP---ARDPINALLNFVYTVLANDCASACQAVGLDPQLGFLHALRP 237

Query: 213 L--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
              S   D+ + ++          +  R    P   V      +  + +    ++  + +
Sbjct: 238 GRSSLALDLMEELRPVIADRAILTLINRQQLTPRDFVLHEGGTVSITEEGRKTILAHLAE 297

Query: 271 VLAAGEIQPPAPPEDA 286
                 + P    +  
Sbjct: 298 RRREEVMHPLTARKTP 313


>UniRef50_B2SPB2 Crispr-associated protein Cas1 n=56 Tax=Bacteria RepID=B2SPB2_XANOP
          Length = 344

 Score =  186 bits (473), Expect = 7e-46,   Method: Composition-based stats.
 Identities = 40/304 (13%), Positives = 93/304 (30%), Gaps = 47/304 (15%)

Query: 11  LKDRVSMIF--LQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           ++ +++ ++       +       V+  +   R  +PV  +  ++      VS   +   
Sbjct: 1   MRRQLNTLYATTDGAWLRKDGANIVMEVERQERARLPVHMLESLVCIGRVAVSPQLLGFC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE------- 121
           ++ G  + ++   G  +     P          Q + + D      +VR +         
Sbjct: 61  SEHGISICYLTPQGRFLARVEGPVSGNVLLRRAQYRRSDDPAGCAAIVRHLLAGKIHNQR 120

Query: 122 ---------------------------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAK 154
                                       R  +       V+ LRG+EG   ++ + +  +
Sbjct: 121 AVLARGWRDHGDCLTDVAAFQHSLKRLKRIPQRVLVETDVDVLRGLEGEAAQSYFGVFGQ 180

Query: 155 QYG-----VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
                   + + GR   P      D  N  +S   + L     +A+ + G  PA+GF+H 
Sbjct: 181 LVRADKPLLRFGGRNRRPPR----DAFNALLSFLYTLLTHDCRSALESVGLDPAVGFLHR 236

Query: 210 GKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPL 267
            +P   S   D+A+  +       A  +  R               +     +   ++  
Sbjct: 237 DRPGRPSLALDLAEEFRPLLGERLALSLINRRQLNERDFQVFDNGAVLLKDDSRKTVLIA 296

Query: 268 IEDV 271
            ++ 
Sbjct: 297 YQER 300


>UniRef50_Q53W21 Putative uncharacterized protein TTHB145 n=3 Tax=Thermus
           thermophilus RepID=Q53W21_THET8
          Length = 315

 Score =  186 bits (472), Expect = 9e-46,   Method: Composition-based stats.
 Identities = 55/275 (20%), Positives = 90/275 (32%), Gaps = 26/275 (9%)

Query: 35  IDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGA 94
            ++       P   V  + L    R+S  A+    + G  + +    G     +G     
Sbjct: 22  EEEGREVAGFPARQVRSVALWGNVRLSTPALVFLLRQGVPVFFYSLEGFLHGVAGAYPDP 81

Query: 95  RSDKLLYQ--------AKLALDEDLRLKVVRKMFELRFGEP---------APARRSVEQL 137
               L  Q        A+  +   LR  +   +   R  E          A     +E+L
Sbjct: 82  HPAHLRAQFAAEGLPLARAFVVGKLRSALA-LLERHRLPEAGGVVEALARAEGASELERL 140

Query: 138 RGIEGSRVRATYALLAKQYGVT-WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAIL 196
           RG EG   R  +  LA+  G   + GR   P      D +N  +S   + L G    A+ 
Sbjct: 141 RGAEGEGSRVYFQGLARLLGPYGFGGRTRRPPR----DPVNAALSYGYALLLGRVLVAVR 196

Query: 197 AAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDI 254
            AG  P +GF+H     S     D+ +  +   V        RR    P     +    +
Sbjct: 197 LAGLHPEVGFLHAEGRRSPALALDLMEEFRVPVVDQVVLSAFRRGLLTP-SHAEVREGGV 255

Query: 255 FRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPV 289
           + + +   +LI L E+ L  G   P    +     
Sbjct: 256 YLNEEGRRRLIQLFEERLLEGVSHPLGFRKPLGET 290


>UniRef50_B9M5J4 CRISPR-associated protein Cas1 n=9 Tax=Bacteria RepID=B9M5J4_GEOSF
          Length = 344

 Score =  185 bits (470), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 36/312 (11%), Positives = 90/312 (28%), Gaps = 47/312 (15%)

Query: 11  LKDRVSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K  ++ +++  Q   + +      +     ++  +P+  +  ++      +S   +   
Sbjct: 1   MKQLLNTLYVMTQGSYLSLDHETVRVEVNGKLQMQVPLHHLGSVVTFGNVMISPFFLGKC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA 128
           A  G  +V +  +G                   Q +   D+     + R M   +     
Sbjct: 61  ADDGRPVVILSRSGRYKCRMVGKTSGNVLLRQAQYEAVRDKGKAAAIARNMVAGKVKNAR 120

Query: 129 ------------PARRS---------------------VEQLRGIEGSRVRATYALL--- 152
                       P   +                     ++Q+RG+EG    A +A+    
Sbjct: 121 QVLMRGARESDSPEEETALRKASEIHADTLFRLKSICEIDQVRGLEGESAAAYFAVFDQM 180

Query: 153 ---AKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
                +     + R   P      D +N  +S   + +     +A+ + G    +GF+H 
Sbjct: 181 VKDGDRAAFAMDNRNRRPP----LDPMNALLSFLYTLVLNDCISAVESVGLDSQMGFLHA 236

Query: 210 GKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPL 267
            +P   S   D+ +  +       A  +  R               ++ +      ++  
Sbjct: 237 LRPGRPSLGLDLMEEFRAVIADRLALTLINRKQITEKDFEPRPGGAVYLNEDGRKTVVVA 296

Query: 268 IEDVLAAGEIQP 279
            +         P
Sbjct: 297 YQKRKQEEFFHP 308


>UniRef50_Q57823 Uncharacterized protein MJ0378 n=20 Tax=Euryarchaeota
           RepID=Y378_METJA
          Length = 322

 Score =  185 bits (470), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 41/293 (13%), Positives = 93/293 (31%), Gaps = 31/293 (10%)

Query: 11  LKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           ++ +   + L  G +   +      +  G +  + +  +  I +     +S  A+   AQ
Sbjct: 1   MRKKSLTL-LSDGYLFRKENTIYFENARGKK-PLAIEGIYDIYIYGKVSISSQALHYLAQ 58

Query: 71  VGTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE-------- 121
            G  L +    G    +   +        ++ Q +  LD+D RL++ +            
Sbjct: 59  KGIALHFFNHYGYYDGSFYPRESLHSGYLVVNQVEHYLDKDKRLELAKLFIIGGIKNMEW 118

Query: 122 --LRFG---------EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWN--GRRYDPK 168
             L+F          E       + ++  +EG      Y L  +     +    R   P 
Sbjct: 119 NLLKFKNKTKFSSYIEELNNCNKITEVMNVEGRVRTEYYRLWDETLPDDFKIVKRTRRPP 178

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFD 226
             E    +N  IS   S LY      +      P + ++H    +  S   D+++I K  
Sbjct: 179 KNE----MNALISFLNSRLYPAIITELYNTQLTPTVSYLHEPHERRFSLALDLSEIFKPM 234

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                A  + ++   +  +  R     +  + + +  ++      +       
Sbjct: 235 IADRLANRLVKQGIIQ-KKHFRDDLNGVLLNKEGMKVVLEHFNKEMDKTVNHK 286


>UniRef50_C0FSR1 Putative uncharacterized protein n=1 Tax=Roseburia inulinivorans
           DSM 16841 RepID=C0FSR1_9FIRM
          Length = 359

 Score =  184 bits (468), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 50/294 (17%), Positives = 93/294 (31%), Gaps = 40/294 (13%)

Query: 14  RVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
             +   +  G +   D   +   + G +  IPV +   + +     +S        QVG 
Sbjct: 31  DHNYHLINEGILTKQDFNILFESENGKKY-IPVETTDSLYIYSNVIMSGNFFDFMNQVGL 89

Query: 74  LLVWVGEAGVRVYASGQPGGARSDKL-LYQAKLALDEDLRLKVVRK-------------- 118
            + ++ + G ++ +       R+ K  L Q ++   E  RL + R+              
Sbjct: 90  NVSFINKYGEKIGSFVPNNSRRNIKTELKQLRMYDSEKERLDMARRLEIASVSNIRANLR 149

Query: 119 MFELR---------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG---VTW 160
            ++ R                       R +  +  +E    +  Y             +
Sbjct: 150 YYQRRKNATELGAAVKDMTDIITKLNEARDINHMMMLEAQARQKYYGCFNSILEGKQFYF 209

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYD 218
           + R   P      D +N  IS   + LY      I        IG VH    +P S   D
Sbjct: 210 DKRTRRPPQ----DPLNAMISFGNTLLYQRIANEINRTSLDIRIGIVHAAGNRPESLNLD 265

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
           +AD+ K   V    F +  R     +  V +    I+ +++     I   E+ L
Sbjct: 266 LADLFKPILVDRTIFTLVNRKMINVNDFVEVENNGIYLNNRAKKIFISEYENKL 319


>UniRef50_B7C8S2 Putative uncharacterized protein n=2 Tax=Eubacterium biforme DSM
           3989 RepID=B7C8S2_9FIRM
          Length = 329

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 47/297 (15%), Positives = 96/297 (32%), Gaps = 38/297 (12%)

Query: 13  DRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
            +V  ++ + G +   D + VL  K     +IP+  V  I+      ++   + L  +  
Sbjct: 2   KKVVYLY-KSGNLKRKDNSLVLESKD-KDDYIPIEQVDMIICFSEVSLNKRVLALLNKYE 59

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR--------------K 118
            L+++    G  +             L+ Q     DE  RL + +              K
Sbjct: 60  VLILFYNFYGNYIGRYAPKDYKDGRVLVNQVNKYRDESQRLYISKSILKASIKNMLSVLK 119

Query: 119 MFELRFGEPAP-------------ARRSVEQLRGIEGSRVRATYALLAKQY---GVTWNG 162
            +  +                      ++ +L  IE +  +  Y +           +  
Sbjct: 120 YYRKKGKNLDELIRKLEDLVGMASDIETMNELMLIEANAKQTYYKMFDVVLENEEFKFQK 179

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIA 220
           R  +P   E    +N  +S   + LYG+  + +  +   P I F+H  +    S  YD+A
Sbjct: 180 RTKNPPQNE----VNAMLSYGYTLLYGIILSILDRSSLFPQISFIHSLSKNSDSLQYDLA 235

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           DI K   +      + R+   +            + S +     I     +L +  +
Sbjct: 236 DIFKPVYIDRMVLRLIRKKQIKQSHFQYKPDGRCYLSKEGTKVFIEEFNILLQSTIV 292


>UniRef50_Q6L317 DNA polymerase n=2 Tax=Thermoplasmatales RepID=Q6L317_PICTO
          Length = 320

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 54/293 (18%), Positives = 99/293 (33%), Gaps = 36/293 (12%)

Query: 15  VSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
            +    Q G+I         + K   R H+PV +V  I++     +S  A+   +++G +
Sbjct: 2   YNFYITQDGEITRDGNTLYFVGKDFKR-HLPVMNVNEIIISAKVSISSWALDYLSKLGIM 60

Query: 75  LVWVGEAGVRVYASGQPGGAR--SDKLLYQAKLALDEDLRLKVVRKMF---------ELR 123
           +  +   G    +S  PG      + ++ Q +  L++D RL +  +M           LR
Sbjct: 61  VHILNIYGN-YMSSLIPGNRNEKGNIIIMQVRSYLNDD-RLYIASQMVLGIKHNILRNLR 118

Query: 124 FGEPA--------------PARRSVEQLRGIEGSRVRATYALLAKQYGVTWNG-RRYDPK 168
           +                  P   ++  + G EG+     Y+     Y       R + P 
Sbjct: 119 YYNKNNALDDKIEKISGYYPDGNNINSILGTEGNIWSTYYSAFPYIYKKYHEFKREFHPP 178

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFD 226
                D +N  IS   S LY     +I   G  P+I ++H    +  S   DI+DI K  
Sbjct: 179 K----DELNAMISFGNSLLYSNVITSIFLNGLNPSISYLHEPSERSFSLALDISDIFKPV 234

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
            V      +   N  + +          + +       I      + +     
Sbjct: 235 IVERVIANLVNNNIIDSN-HFTKENNGYYLNDNGRKIFINYYNQKMNSTINIK 286


>UniRef50_C6CA70 CRISPR-associated protein Cas1 n=56 Tax=Bacteria RepID=C6CA70_DICDC
          Length = 333

 Score =  184 bits (468), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 65/314 (20%), Positives = 117/314 (37%), Gaps = 52/314 (16%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGI---RTHIPVGSVACIMLEPGTRVS 61
            L  I    R ++ +LQ+ +I V  G    + + G      +IP+ + + +ML  GT V+
Sbjct: 9   DLKTILHSKRANIYYLQHCRILVNGGRVEYVTEEGNQSLYWNIPIANTSVVMLGTGTSVT 68

Query: 62  HAAVRLAAQVGTLLVWVGEAGVRVYAS-----------GQPGGARSDKLLYQAKLALDED 110
            AA+R  A+ G ++ + G  G  ++A+            Q     ++ L        +E 
Sbjct: 69  QAAMREFARAGVMVGFCGSGGTPLFAANEAEVAVSWLSPQSEYRPTEYLQDWVSFWFNEQ 128

Query: 111 LRLKVVRKMFELRFGE----------PAPARRSV-----EQLRGI--------------- 140
            RL       ++R G+             +R ++     E L                  
Sbjct: 129 QRLAAAIAFQQVRIGQIRQHWLGGRLARESRFTIKPEHVEALLNRYQQGLVDCRTSNDVL 188

Query: 141 --EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAA 198
             E    +A Y L A        G     K     D  N+ +       YG+   A+   
Sbjct: 189 VQEAMMTKALYRLAANAVSY---GDFTRAKRGGGTDLANRFLDHGNYLAYGLAAVALWVL 245

Query: 199 GYAPAIGFVH-TGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRS 257
           G    +  +H   +    V+D+AD+IK   ++P+AF  A       +++ R  C   FR 
Sbjct: 246 GLPHGLAVLHGKTRRGGLVFDVADLIKDALILPQAFIAAMEGE--DEQDFRQRCLTAFRQ 303

Query: 258 SKTLAKLIPLIEDV 271
           ++ L  +I  ++ V
Sbjct: 304 AEALDVMIDSLQQV 317


>UniRef50_Q0AW57 CRISPR-associated protein, Cas1 family n=1 Tax=Syntrophomonas
           wolfei subsp. wolfei str. Goettingen RepID=Q0AW57_SYNWW
          Length = 336

 Score =  183 bits (466), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 41/306 (13%), Positives = 89/306 (29%), Gaps = 41/306 (13%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHI-PVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +S +++  +  +I V +   V+  K      I P+  V  +++     +S   V+   + 
Sbjct: 1   MSFLYVYERSAKIGVQENCVVVESKKENLKRILPIEGVENVIIFGDASLSSNCVKQFMER 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA--- 128
              L W+   G               +   Q     D++  L + +++   +        
Sbjct: 61  DINLTWLSSRGKFYGRLESTRNVNIYRQRKQFACGEDDEFCLALAKRIILAKVKNQITIL 120

Query: 129 --------------------------PARRSVEQLRGIEGSRVRATYALLAKQY--GVTW 160
                                         + ++L G EG   R  Y  LA+       +
Sbjct: 121 RRYRRNRPEKSVQKIIDAMAKLLPIMERVHNKDELMGHEGMAARYYYQGLAELVEPDFAF 180

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYD 218
           +GR   P      D  N  +S A + L      A +  G  P   F+H+ +    +   D
Sbjct: 181 SGRNRQPPR----DPFNSLLSFAYTLLMYDLYTAAVNRGLNPYASFLHSIRRGHPALCSD 236

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRL-ACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           + +  +       A  +  +   + +   +      ++         I   E  +     
Sbjct: 237 LMEEWRAILADSLALYVTSKGIIKRENFEKPNEEGGVYLDGIGSKAFIAEYEKKVRGRSN 296

Query: 278 QPPAPP 283
                 
Sbjct: 297 YLAYVD 302


>UniRef50_B8G918 CRISPR-associated protein Cas1 n=5 Tax=Chloroflexi (class)
           RepID=B8G918_CHLAD
          Length = 339

 Score =  183 bits (466), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 54/318 (16%), Positives = 101/318 (31%), Gaps = 48/318 (15%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           ++ +++  Q  +I        +     I   +P+  +  I++     +S  A++     G
Sbjct: 1   MATLYVIEQGAEIGCDGERIEVRRGADIIGSVPLVKLDDIVIFGNVGISTPAMKRLLDRG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP----- 127
             + ++   G           A       Q   A D    L + ++  E +         
Sbjct: 61  IEVTFMTVDGRYQGRLIGQVTAHVALRHAQYACAADPARALALAQRFVEGKLRNQRALLQ 120

Query: 128 --------------------------APARRSVEQLRGIEGSRVRATYALLAKQYGVTWN 161
                                           +  L G+EGS     +A L    G  W+
Sbjct: 121 RFSRNRAEPPPEAQAAADDLEAYIKRVKRTTQLSSLLGVEGSATARYFAGLRSLIGPEWS 180

Query: 162 --GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFV 216
             GR+  P      D +N  +S   + L      A+ AAG+ P +GF+H+   G+P S  
Sbjct: 181 FSGRQRRPPP----DPVNLLLSLGYTLLAHKVLGAVQAAGFDPYLGFLHSLDYGRP-SLA 235

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVR--LACRDIFRSSKTLAKLIPLIEDVLAA 274
            DI +  +   +      I       P+   R     R I  + +     +   E+ +  
Sbjct: 236 LDIMEEFRPILIDSLVVRICNDGRIRPE-HFRPGEGERPIIITDEGKRAFLTAFEERMRT 294

Query: 275 GEIQPPAPPEDAQPVAIP 292
               P     D+ P  +P
Sbjct: 295 EATHPEGA--DSGPGKVP 310


>UniRef50_A4X3M4 CRISPR-associated protein, Cas1 family n=4 Tax=Actinomycetales
           RepID=A4X3M4_SALTO
          Length = 326

 Score =  182 bits (462), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 52/290 (17%), Positives = 91/290 (31%), Gaps = 30/290 (10%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           S    +  +I   D +  +    G    IP+  +  ++L     ++ AAV L ++ G  +
Sbjct: 7   SYWLTEPCRIRREDNSIRIERADGQPVRIPITDIRDLVLFDNADINTAAVSLLSRHGVTV 66

Query: 76  VWVGEAGVRVYASGQPGG-ARSDKLLYQAKLALDEDLRLKVVRKMFEL------------ 122
             +   G    A       + +  +  Q  L  +   RL V + +               
Sbjct: 67  HLLDHYGNYAGALTPADDMSSAHVVRAQVALTGNPQARLAVAQALVRATAVNVAWALGTD 126

Query: 123 -------RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNGRRYDPKDWEKG 173
                  R      A  S   L G+EG+  R  + +L       +  +GR   P      
Sbjct: 127 LLDGPLERLPAQIGASTSSGDLMGVEGNFRRTAWGVLDTLLPPWLRLDGRTRRPP----S 182

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG---KPLSFVYDIADIIKFDTVVP 230
           +  N  IS   +  Y     AI      PAIGF+H     +  +   D+A+  K      
Sbjct: 183 NAGNAFISYLNAITYARVLTAIRCTPLHPAIGFLHADTDRRRNTLALDLAEPFKPLLAER 242

Query: 231 KAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
                A +       +     R    S     K+  ++ + LA       
Sbjct: 243 LLRRAAAQRTLTA-ADFVSDVRSASLSQAGRKKIAVMVREELATTVQHRQ 291


>UniRef50_C9RRG3 CRISPR-associated protein Cas1 n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RRG3_FIBSS
          Length = 343

 Score =  182 bits (461), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 46/322 (14%), Positives = 92/322 (28%), Gaps = 44/322 (13%)

Query: 15  VSMIFLQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
           + +   + G ++    G  V+         I +  V  + L      +  A+      G 
Sbjct: 1   MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGA 60

Query: 74  LLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL----------- 122
            + ++   G          G      L Q  +  D+D    + +                
Sbjct: 61  DIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEA 120

Query: 123 ---------RFGEPAP-----------ARRSVEQLRGIEGSRVRATYALLAKQY--GVTW 160
                    RF                     ++LRG EG+  R  +    +    G+ +
Sbjct: 121 YSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDF 180

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYD 218
            GR+Y P      D +N  +S   +      E+ + + G  P +G++H       S   D
Sbjct: 181 PGRKYHP----STDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQD 236

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRL----ACRDIFRSSKTLAKLIPLIEDVLAA 274
           + +  +   V      +  R     D   +     +   +F   + +   +   ED +A 
Sbjct: 237 MLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVAR 296

Query: 275 GEIQPPAPPEDAQPVAIPLPVS 296
                           + L V 
Sbjct: 297 PNGIYQGLANLPWRSVMRLRVE 318


>UniRef50_B5IHG3 CRISPR-associated protein Cas1 n=3 Tax=Aciduliprofundum boonei T469
           RepID=B5IHG3_9EURY
          Length = 321

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 52/305 (17%), Positives = 95/305 (31%), Gaps = 31/305 (10%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           S+   +   I        L+ K G +  IP+ ++  I        S  A++     G ++
Sbjct: 3   SLYITKEAIIKREANTIYLVRK-GEKRSIPIHNLRDITCIAPVSFSSGAIKHVLNSGVVV 61

Query: 76  VWVGEAGVRVYA-SGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE------------- 121
            +    G        +      + ++ QAK  +  + R  + ++M E             
Sbjct: 62  HFFDMYGNYEGTLYPRERSISGEVVVNQAKHYIFWEKRKYIAKEMIEGIKHNILRNLKKS 121

Query: 122 --------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG-VTWNGRRYDPKDWEK 172
                    +         S+E+L   E       Y  L           R Y P     
Sbjct: 122 NKELEEIIEKIERVEVEGDSIEELMNREAQIWGYYYKSLDYTLKKFQLERRDYRPP---- 177

Query: 173 GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVP 230
            + +N  IS   + LY      I      P+I ++H    +  S   DIAD+ K   V  
Sbjct: 178 INELNALISFGNTLLYSAVLTEIYHTHLNPSISYLHEPSERRFSLSLDIADVFKPTMVYR 237

Query: 231 KAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVA 290
              +I        + + R     +F + +   K I   ED +++           +Q   
Sbjct: 238 HIHDIVNHGIIT-EDDFRKEFNGVFLNEQGKRKYIRKWEDRMSSTVYHRRLKRSVSQRGL 296

Query: 291 IPLPV 295
           + L  
Sbjct: 297 LRLEA 301


>UniRef50_UPI0000F51762 hypothetical protein Faci_00015 n=1 Tax=Ferroplasma acidarmanus
           fer1 RepID=UPI0000F51762
          Length = 328

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 42/290 (14%), Positives = 87/290 (30%), Gaps = 32/290 (11%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
              +    + V  G  ++ +  G    IPV +V  +       +S   V + +++G  + 
Sbjct: 6   YHIIHESTVYVDGGTIIIENSIGKNA-IPVENVRSVYAHKPVSISSGVVSIISKLGIPIH 64

Query: 77  WVGEAGVRVYASGQ-PGGARSDKLLYQAKLALDEDLRLKVVRKMFE-------------- 121
           +    G               D ++ QA+  LD   R+ + +                  
Sbjct: 65  FFNWYGNYEATLWPKSKDISGDVIIKQAQKYLDIHERINIAKSFVSGALHNFNRILSEYD 124

Query: 122 ----LRFGEPAPA-------RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDW 170
                +  E   +          + ++ GIEG    + +  +       +  R       
Sbjct: 125 TETVKKSREDIKSNIGNLTNAMDITEIMGIEGRSHNSYFKAMDSVIPEKF--RINKRIRR 182

Query: 171 EKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTV 228
             G+  N  IS   S +Y      I      P I ++H    +  S   DIA+I K    
Sbjct: 183 PPGNMGNALISFGNSLVYASVLTEIYFTHLNPTISYLHEPSERRFSLSLDIAEIFKPIIS 242

Query: 229 VPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
                 +  +     + +   +   +  + K     +   E+ L +    
Sbjct: 243 HKLFLYLINKKIIN-ENDFDNSLEKVILNEKGKKLYLKNYEEKLTSTVFH 291


>UniRef50_Q65S18 Putative uncharacterized protein n=1 Tax=Mannheimia
           succiniciproducens MBEL55E RepID=Q65S18_MANSM
          Length = 333

 Score =  181 bits (460), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 46/293 (15%), Positives = 94/293 (32%), Gaps = 39/293 (13%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +  +++     ++ V     +  +K      IP+ SV  + ++    +  + +    + G
Sbjct: 1   MPTLYIDRRTTELKVNGDVLICYEKGERIATIPLASVDRLYMKGDINLQISLLSKLGEKG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR--------- 123
             +V++     +           + + + Q  LA ++   L + + +   +         
Sbjct: 61  IGVVFLQGRKNKPMQFLPQPHNDAYRRVTQTYLADNKLFCLTLAKNIVLNKCIKQCQFLA 120

Query: 124 ------------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNGR 163
                                    + +++ LRGIEG      +A  A      + +NGR
Sbjct: 121 KFIEHNPKIITFIAELQKLFNLIVKQENIDSLRGIEGRMGAIYFAAFADILPRSLGFNGR 180

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIAD 221
              P      D +N  +S   + LY     A+  AG  P IGF HT      S   D+ +
Sbjct: 181 NRRPPK----DPVNAVLSLTYTLLYSEATLAVYGAGLDPYIGFFHTLHFGRKSLSCDLME 236

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
            I+   V     E       + D+             +         E V++ 
Sbjct: 237 PIRPS-VDEWIAECFTAEVLKIDQ-FSQTNEGCILGKEGRVIFYTAFEKVVSE 287


>UniRef50_C7RP03 CRISPR-associated protein Cas1 n=1 Tax=Candidatus Accumulibacter
           phosphatis clade IIA str. UW-1 RepID=C7RP03_9PROT
          Length = 339

 Score =  180 bits (458), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 52/343 (15%), Positives = 106/343 (30%), Gaps = 63/343 (18%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           ++ +++      +     A V  +       +P+  ++ + +     +S A +    + G
Sbjct: 1   MTSLYVDRRGVTLKADGEALVFYENGERIGTVPLAPLSRVFMRGDVTLSSALLGKLGERG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP----- 127
             +V +                 + + + Q +L+LD D  L+  R + E +         
Sbjct: 61  IGVVVLSGRKAVPTMLLGRPHNDAARRVAQYRLSLDGDFCLRFARAIVEAKLRAQATFLT 120

Query: 128 --------------------------APARRSVEQLRGIEGSRVRATYALLAKQYG--VT 159
                                        + S+  LRG+EG+   A +   A      + 
Sbjct: 121 ERRDSEPHSRYLLTLSLRRLATSIAAVDEQGSLGSLRGLEGAGAAAYFEGFADLLPERLK 180

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVY 217
           ++GR   P      D +N  +S   + L+     A+  AG  P +GF H       S   
Sbjct: 181 FSGRNRRPPR----DPVNAMLSLGYTLLHAEAVLALYGAGLDPFVGFYHALDFGRESLAC 236

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDV------ 271
           D+ + ++ + V   A  + R      +                 A+     E+V      
Sbjct: 237 DLVEPLRVE-VDRHALMLFRSEKLRAEG-FSTTESGCLLGKAGRARFYGEWEEVAARLRK 294

Query: 272 -------------LAAGEIQPPAPPEDAQPVAIPLPVSLGDAG 301
                        + A  ++ P  P    P A    V+  + G
Sbjct: 295 LLAESVSDVASAIMQAAAVEAPCSPPIGDPAA-DAGVADEETG 336


>UniRef50_A4FJX8 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Saccharopolyspora
           erythraea NRRL 2338 RepID=A4FJX8_SACEN
          Length = 549

 Score =  180 bits (458), Expect = 4e-44,   Method: Composition-based stats.
 Identities = 47/314 (14%), Positives = 85/314 (27%), Gaps = 45/314 (14%)

Query: 4   LPLNPI-PLKDRVSMIFLQYGQ-IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVS 61
            P   +     R  +   + G  + +      +           +  V  ++     +V+
Sbjct: 207 KPRKLLARAPARDPVYVTEPGTTVGIRSERLAVRKDHEELLSCRLRDVLHLVAAGPVQVT 266

Query: 62  HAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE 121
             AV   A+ G+ +VW    G          G   +    Q       +  L   R++  
Sbjct: 267 SQAVHALAEQGSPVVWTSTTGRLKSVDIPTVGKHVELRRRQFTA--TPNTALDFARRIVG 324

Query: 122 LRFGEPA-------------------------PARRSVEQLRGIEGSRVRATYALLAKQY 156
            +                                  +   L GIEG+  R  +A L + +
Sbjct: 325 GKIRNARTLLRRNPHVEEPDLLNRLDADAVRAERAPTRSTLLGIEGAAARTYFAGLVETF 384

Query: 157 GVTWN---------GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFV 207
                         GR   P      D ++  +S     L      A  A G  P  GF 
Sbjct: 385 RTDHRLPGPAFDTMGRTRRPPR----DAVSCLLSFLYCLLIKDITTACYALGLDPYFGFY 440

Query: 208 HTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLI 265
           H  +    +   D+A+  +       A  +      +P     +    +  +S     +I
Sbjct: 441 HQPRHGRPALTLDLAEEFRPLIADSTALTLINNLQADPAM-FHVHSTAVALTSSGRRDVI 499

Query: 266 PLIEDVLAAGEIQP 279
              E  L    I P
Sbjct: 500 DAYERRLTTEVIHP 513


>UniRef50_D1N0J7 CRISPR-associated protein Cas1 n=1 Tax=Victivallis vadensis ATCC
           BAA-548 RepID=D1N0J7_9BACT
          Length = 347

 Score =  180 bits (457), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 42/313 (13%), Positives = 86/313 (27%), Gaps = 53/313 (16%)

Query: 18  IFLQY-GQIDVIDGAFVLIDKTGIRTH-------------------IPVGSVACIMLEPG 57
           ++L   G++   D            T                    +PV S+  + +   
Sbjct: 3   LYLTRSGRLRRRDNTLRFERVNLPETEDPEVEAEALEEGKADAVQALPVESIDAVYVFGE 62

Query: 58  TRVSHAAVRLAAQVGTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVV 116
             V+   +         + +    G               D ++ Q +   + + RL + 
Sbjct: 63  LSVNTKLINFLNCKKVPVHFFNWYGHHTGTLLPHAEQLSGDLVIRQGEAYRNPEERLMIC 122

Query: 117 R--------------KMFELR-------------FGEPAPARRSVEQLRGIEGSRVRATY 149
           R              + ++ R               +    + + E L G+EG+  +  Y
Sbjct: 123 RNLLEAVFHNILSVLQYYQRRKGGLEKSIAAVKELEQKLAEQDTPEGLMGLEGNVRKLYY 182

Query: 150 ALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
                  G       +        + +N  IS   S LY    + +      P I ++HT
Sbjct: 183 QSWPVWLGK--TAEHFKRVYHPPDNPLNALISFLNSLLYTACVSELYRTALYPGISYLHT 240

Query: 210 G--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPL 267
              +  S   D+ +  K   V    F +        DR+ R        +     +++  
Sbjct: 241 PQTRRFSLALDLVEPFKPLLVDRMIFRLLDSRAIG-DRDFRKHSNGFLLTDDARRRILQE 299

Query: 268 IEDVLAAGEIQPP 280
            +  L       P
Sbjct: 300 WDQELRRTVHYAP 312


>UniRef50_D0MJ58 CRISPR-associated protein Cas1 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MJ58_RHOM4
          Length = 360

 Score =  179 bits (455), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 44/341 (12%), Positives = 80/341 (23%), Gaps = 65/341 (19%)

Query: 14  RVSMIFLQYGQIDVIDGAFVLIDKTGIR-------------------THIPVGSVACIML 54
           +        G++             G R                   T  PV  V  +  
Sbjct: 2   KRPYYIFSSGRLRRRQNTLFFEKAAGERIPDDQDETGVPSGTPTGESTPFPVEQVESLYF 61

Query: 55  EPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRL 113
                ++   +   A+      +    G        +         + Q    +    R 
Sbjct: 62  FGEVDLNSKLLTFLARHDIPAHFYDYYGNYTGTYIPRDYLHSGRLRIEQVLHYVRPKRRR 121

Query: 114 KVVR--------------KMFELRFGEP------------------APARRSVEQLRGIE 141
            + R              + +  R                        +   + +L GIE
Sbjct: 122 YLARAIVEAATYNLLRVLRYYVNRLEGERREAVAEAIATIEQERTQLRSAEKIPELMGIE 181

Query: 142 GSRVRATYALLAKQYG------VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAI 195
           G    A Y+               +  R   P      + IN  IS   S  Y  T   I
Sbjct: 182 GRSREAYYSAWPSILADGPGEAFVFEKRERRPP----SNEINALISFGNSLCYTTTIRQI 237

Query: 196 LAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRD 253
                 P I ++H    +  S   D+++I K   V    F + +     P R        
Sbjct: 238 HRTALDPTISYLHEPGARRFSLALDLSEIFKPILVDRAIFRLVKTGEITP-RHFEERLGG 296

Query: 254 IFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLP 294
           ++   +     +   ++ L             +    I L 
Sbjct: 297 VYLKEEGRRIFVRHWDERLRQTVYHRRLERHVSYERLIRLE 337


>UniRef50_C8Q0H7 CRISPR-associated protein Cas1 n=6 Tax=Proteobacteria
           RepID=C8Q0H7_9GAMM
          Length = 334

 Score =  179 bits (454), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 57/305 (18%), Positives = 118/305 (38%), Gaps = 42/305 (13%)

Query: 7   NPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKT----GIRTHIPVGSVACIMLEPGTRVSH 62
            P+ L  R  + +L+  ++ + D   V + ++        +IP  + A ++L  G+ ++ 
Sbjct: 27  RPLMLSKRACVFYLERVRVILKDDRIVYLTESMQPIEHFYNIPEKNTAFLLLGKGSSITD 86

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYAS-------GQPGGARSDKLLYQAKLALDEDLRLKV 115
           AA R  A+   ++ + G  G  ++++        Q     ++ +    K  LD+  RL +
Sbjct: 87  AAARRLAESNVMVGFCGSGGSPLFSALDLTFLAPQSEYRPTEYMQIWMKAWLDDTTRLLM 146

Query: 116 VRKMFELR----------------------------FGEPAPARRSVEQLRGIEGSRVRA 147
            + + + R                            F +   +  + EQL   EG   + 
Sbjct: 147 AKVLLQERIEIVKKYWQKNPLLTSYGIRLDESAVVNFSQAIESAMNQEQLLTAEGRWAKV 206

Query: 148 TYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFV 207
            Y  LA+  G  +        + +  D  N  +       YG    A+   G + A+  +
Sbjct: 207 LYKSLAEGCGFKFTREEGKNANDDIADIANSYLDHGNYIAYGYAAVALHGLGISFALPML 266

Query: 208 H-TGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIP 266
           H   +    V+D+AD++K   V+P+AF  A+   G   +E R+   +I +    L  +  
Sbjct: 267 HGKTRRGGLVFDVADLVKDAMVMPQAFISAK--LGHNQKEFRMQLIEICQDQDVLDYMFG 324

Query: 267 LIEDV 271
            + + 
Sbjct: 325 FVVET 329


>UniRef50_UPI0001C41A73 CRISPR-associated protein Cas1-2 n=1 Tax=Methanobrevibacter
           ruminantium M1 RepID=UPI0001C41A73
          Length = 334

 Score =  178 bits (453), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 44/289 (15%), Positives = 80/289 (27%), Gaps = 42/289 (14%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           +   D   V+ +      +     ++ I+L     ++  A+ L A+     V +   G  
Sbjct: 12  VAKRDNQIVIKENGKEINYYLAKDISQILLTGKGSITFDALTLLAENDVDCVSINWKGHV 71

Query: 85  VYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP----------------- 127
            Y    P    +     Q     D      + +     +                     
Sbjct: 72  DYRLSAPDRKNAIVKKEQYFALTDSRSG-YLAKAFVRAKIENQKAVLGTLAKSREEKDYI 130

Query: 128 -------------------APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPK 168
                                +      + GIEG      ++  A      W    +   
Sbjct: 131 IEQREKVSEHIGKIEKLSNINSDNIRNNILGIEGQASHEYWSAFASVLDEKWEF--FGRS 188

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFD 226
                D +N  ++   + +      +I  AG  P  GF+H+ +    S VYD+ +  +  
Sbjct: 189 GRGAKDPVNSLLNYGYAVIESEIWKSIYLAGLDPYCGFLHSERYGRASLVYDLIEEFRQQ 248

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
            V      I  RN   PD +       I    +    LI  I D L + 
Sbjct: 249 IVDKTVLSIVNRNQITPD-DFEEDGNYIKIHERARRLLIAKILDKLNSK 296


>UniRef50_D1VVR4 CRISPR-associated endonuclease Cas1, DVULG subtype n=1
           Tax=Peptoniphilus lacrimalis 315-B RepID=D1VVR4_9FIRM
          Length = 343

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 38/310 (12%), Positives = 87/310 (28%), Gaps = 45/310 (14%)

Query: 11  LKDRVSMIFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           +K  ++++++      +       V+  +       P+  +  ++      VS   +++ 
Sbjct: 1   MKKLLNVLYVTSPDYYLKKEGRNIVISLEGKRVARYPIHILRQVVCFNYMGVSPDLMKMC 60

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDED-----LRLKVVRKMFELR 123
            +    + +    G                   Q KLA  E+       +   +     +
Sbjct: 61  MEENVSISFFTPYGKYCGRVVGASYGNIYNRKRQYKLAESEESLQFVKNIIYAKAYNSRK 120

Query: 124 --FGEPAPARRSV-------------------------EQLRGIEGSRVRATYALL---- 152
                    +  +                         + +RGIEG+  R  +++L    
Sbjct: 121 IIIRGKLDHKDKIDLEKVENVISNIKDLMIQIQYSPDKDSIRGIEGTIARQYFSVLDEFI 180

Query: 153 -AKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK 211
             ++    +  R   P      D  N  +S   S L     +A+   G     GF HT +
Sbjct: 181 VKQREDFYFIERTKRPPR----DRFNAMLSFMYSILTNSIASALEGVGIDSYAGFFHTDR 236

Query: 212 PL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIE 269
           P   S   DI + ++   +      +   N    +            + K    ++    
Sbjct: 237 PGRVSMALDIIEEMRAFIIDKFCLSMINLNRINKNNFEIKENGACLLNDKGREIILQNWN 296

Query: 270 DVLAAGEIQP 279
                  + P
Sbjct: 297 KKQQEEILHP 306


>UniRef50_A9BUF1 CRISPR-associated protein Cas1 n=33 Tax=Proteobacteria
           RepID=A9BUF1_DELAS
          Length = 337

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 65/334 (19%), Positives = 121/334 (36%), Gaps = 56/334 (16%)

Query: 5   PLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIR---THIPVGSVACIMLEPGTRVS 61
            L  I    R ++ +L++ ++ V  G    +   G R    +IP+ +   I+L  GT ++
Sbjct: 8   DLKTILHSKRANIYYLEHCRVLVNGGRVEYVTDAGKRSLYWNIPIANTTSILLGAGTSIT 67

Query: 62  HAAVRLAAQVGTLLVWVGEAGVRVYAS-----------GQPGGARSDKLLYQAKLALDED 110
            AA+R  A+ G L+ + G  G  ++++            Q     ++ L    +   D++
Sbjct: 68  QAAMRELAKAGVLVGFCGGGGTPLFSANEVDVEVAWLTPQSEYRPTEYLQAWVQFWFDDE 127

Query: 111 LRLKVVRKMFELR-------------------------------FGEPAPARRSVEQLRG 139
           LRL   +++  LR                               F         V  L  
Sbjct: 128 LRLHAAKQLQALRLQRLQQEWGARALRESGFAVDMERLKALVQQFAALMANAPDVMTLLT 187

Query: 140 IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAG 199
            E    +A + L     G    G     K     D  N+ +       YG+   A    G
Sbjct: 188 DEARLTKALFKLAVDAVGY---GEFTRAKRGTGTDGANRYLDHGNYLAYGLGATATWVLG 244

Query: 200 YAPAIGFVH-TGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSS 258
               +  +H   +    V+D AD++K   ++P+AF  A R   + + + R  C +    S
Sbjct: 245 LPHGLAVLHGKTRRGGLVFDAADLVKDAAILPQAFLSAMRG--DDEPQFRRQCIEALTRS 302

Query: 259 KTLAKLIPLIEDVL-----AAGEIQPPAPPEDAQ 287
           ++L  +I  ++ +       AG    P   ++A 
Sbjct: 303 ESLDFIIDTLKRIAVDTARMAGASATPGAAQEAG 336


>UniRef50_Q6L363 DNA polymerase n=1 Tax=Picrophilus torridus RepID=Q6L363_PICTO
          Length = 318

 Score =  178 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 43/282 (15%), Positives = 103/282 (36%), Gaps = 26/282 (9%)

Query: 15  VSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
            +   +  G ++    +    +    +  IP+ ++  I++     ++  A+ + ++    
Sbjct: 2   QTYYIISSGTLNREMDSLRFSNSNENKI-IPLENIESIIISGNVSITKPAISILSKKNIP 60

Query: 75  LVWVGEAGVRVYASGQPGGA-RSDKLLYQAKLALDEDLRLKVVR---------------- 117
           + ++      + +            ++ QA  A + D R+K+ R                
Sbjct: 61  VFFMSMYDNYISSLIPEDYLLSGKVIMNQAIKAYNIDERIKIARIFVYAAARNMAIVLKR 120

Query: 118 -KMFELRFG-EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDT 175
             M +++   +     +S+ +L   EG+  R  +  +  QY +  N +          + 
Sbjct: 121 GNMGKIKIPYKEIMESKSINELMSYEGNF-RNNFLNIVDQY-LPNNYKIIKRSRRPPRNK 178

Query: 176 INQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAF 233
           +N  IS     LY +TE+ I      PAI F+H    +  S   D+++I K       A 
Sbjct: 179 MNALISYLNMLLYSITESQIFLTHLNPAISFLHEPFERRNSLSLDVSEIFKPLICDRLAI 238

Query: 234 EIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
           ++ +    +      L    +F +     K++ + +D +   
Sbjct: 239 KMVKLKIIKDSDF--LEENGVFLNENGRKKVVKMFDDKMQET 278


>UniRef50_B7A8Y4 CRISPR-associated protein Cas1 n=1 Tax=Thermus aquaticus Y51MC23
           RepID=B7A8Y4_THEAQ
          Length = 316

 Score =  177 bits (449), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 49/278 (17%), Positives = 82/278 (29%), Gaps = 34/278 (12%)

Query: 35  IDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGA 94
            +K       P   V  + +    R+S  A+    + G  + ++   G     +G     
Sbjct: 22  EEKGVKVGSFPARQVRRVAVWGNVRLSTPALVFLLRQGAPVFFLSLEGFLYGVAGAFPDP 81

Query: 95  RSDKLLYQAKLALDEDLRLKVVRKMFELR------------FGEPAP---------ARRS 133
               L  Q          L + R     +              E              + 
Sbjct: 82  HPAHLRAQFGA-----EALPLARAFVLGKLRSALALLLRHGLPEAEEVAQALARAGEAQR 136

Query: 134 VEQLRGIEGSRVRATYALLAKQYG-VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTE 192
           +E LRG EG   RA +  L +      + GR   P      D +N  +S   + L G   
Sbjct: 137 LESLRGAEGEGSRAYFQGLGRLLAAQGFGGRTRRPPR----DPVNAALSYGYALLLGRVL 192

Query: 193 AAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLA 250
            A+  AG  P +GF+H     S     D+ +  +   V        RR    P       
Sbjct: 193 VAVRLAGLHPEVGFLHAEGRRSPALALDLMEEFRVPVVDAVVLSAFRRGHLTP-AHAEAR 251

Query: 251 CRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQP 288
              ++ + +   +LI L+E         P    +    
Sbjct: 252 EGGVYLNEEGRRRLIELLEGRFLEEVAHPLGFRKPLGE 289


>UniRef50_B8GSH8 CRISPR-associated protein Cas1 n=1 Tax=Thioalkalivibrio sp.
           HL-EbGR7 RepID=B8GSH8_THISH
          Length = 691

 Score =  176 bits (446), Expect = 9e-43,   Method: Composition-based stats.
 Identities = 40/287 (13%), Positives = 78/287 (27%), Gaps = 38/287 (13%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGE 80
           +  ++ +  G   +          P+ ++A + L    +VS   +      G  L     
Sbjct: 371 EPARVGLDGGRLRVQRGEAELLSAPLETLAGVTLLGPHQVSTQLLGALLDRGIPLALATG 430

Query: 81  AGVRVYASGQPGGARSD--KLLYQAKLALDEDLRLKVVRKMFELRFGEPAP--------- 129
            G             +     + QA    D+   L+  R + + R  +            
Sbjct: 431 QGRLRGVLWNGVPGDAGPGLWMRQAACFEDDARALEAARAVVDARLRQQREVLRNRMSPE 490

Query: 130 -----------------ARRSVEQLRGIEGSRVRATYALLAKQYGVT--WNGRRYDPKDW 170
                            A      L G+EG   R  +  LA+       + GR   P   
Sbjct: 491 RCDDLLPRLDRLIAKTAAASDRASLNGLEGQAARLYFGALAELLPPELGFTGRNRRPPR- 549

Query: 171 EKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFDTV 228
              D  N  +S   + L+   +  +   G  P  GF H       +   D+ +  +   V
Sbjct: 550 ---DPFNVLLSLGYTVLHAHVDTVVRLNGLYPWRGFYHQPHGLHPALASDLMEPFR-HLV 605

Query: 229 VPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
              A  +  R       +           +    + +  + + L   
Sbjct: 606 ERVALNVVARGRIRV-SDFAQQGDACRIEAGARRRYLADLSERLLTP 651


>UniRef50_C8W3G7 CRISPR-associated protein Cas1 n=24 Tax=Bacteria RepID=C8W3G7_DESAS
          Length = 335

 Score =  176 bits (446), Expect = 9e-43,   Method: Composition-based stats.
 Identities = 42/290 (14%), Positives = 81/290 (27%), Gaps = 37/290 (12%)

Query: 18  IFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVW 77
                G +   D +     + G    IP+     +       +S   ++L A+ G ++ +
Sbjct: 9   YIFSAGDLYQKDFSIAFRKEDGNFY-IPIKDTRELYCFNDITLSTKLLQLLAKAGIVVHF 67

Query: 78  VGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLK------VVRKMF---------- 120
            G     +     +         + QA       L++       + +  +          
Sbjct: 68  FGYYENYIGTFYPKEQLLSGRLTVAQALAYEQNRLQIAGQIIKGIAKNTYFVLYHYYRHG 127

Query: 121 -----------ELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW--NGRRYDP 167
                               +  +++QL  IEG      Y         ++  N R   P
Sbjct: 128 KSELKDFLDWLRKDVSRLVDSVGNIKQLLRIEGEIWARFYQSFRVFLPESFAMNKRVKRP 187

Query: 168 KDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKF 225
            D    + IN  IS   + LY  T   I        I F+H    +  S   D++++ K 
Sbjct: 188 PD----NPINALISFGNTLLYTKTITQIFHTHLNQTISFLHEPAERRFSLSLDLSEVFKP 243

Query: 226 DTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
             V    F+         ++           +       I   E+ L   
Sbjct: 244 VLVCKTIFDCVNNRKIMVEKHFDKKLNYALLNELGRKVFIEAFEERLNQT 293


>UniRef50_Q74N45 NEQ017 n=1 Tax=Nanoarchaeum equitans RepID=Q74N45_NANEQ
          Length = 333

 Score =  175 bits (445), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 52/297 (17%), Positives = 96/297 (32%), Gaps = 42/297 (14%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           ++  L  G++         I+K   ++ IP+ S+  I +     V++ A++L A     +
Sbjct: 3   TIYILSIGKLYRGKNGLYFINKDKKKSPIPLESIKEIFILNKVSVTYNALKLLADRNIPI 62

Query: 76  VWV---GEAGVRVYASGQPG---GARSDKLLYQAKLALDEDLRLKVVRKMF--------- 120
            +     + G+  Y               L+ Q +   D + R ++  ++          
Sbjct: 63  HFFYENTKKGISYYLGSFLPRQKTKSGLVLVKQVEAYKDIEKRTEIALEIVDAIRYNCIK 122

Query: 121 -----------ELR-------FGEPAPA-RRSVEQLRGIEGSRVRATYALLAKQYGVT-W 160
                      ELR       F E     + ++  +RGIE +     Y  L K   +   
Sbjct: 123 VLEKYHIDEVKELRKIDVWKMFEESLNDWKDAINIIRGIESNIWNLFYQGLDKILKLYKL 182

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYD 218
             R   P   E     N  +S A + LYGVT   I      P I F+H       S   D
Sbjct: 183 ERRTRRPPKNEA----NTIVSFANTLLYGVTLTEIYKTHLDPTISFLHELRDTRYSLALD 238

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
           +++  K          +  +   + D         +  + +    +I      L   
Sbjct: 239 LSENFKPIITFRILIWLVNQGIIK-DTHFVKGLNGVLLNEQGKKLVIKEFNKRLDET 294


>UniRef50_Q8YZS6 Alr0381 protein n=6 Tax=Cyanobacteria RepID=Q8YZS6_ANASP
          Length = 374

 Score =  175 bits (444), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 45/310 (14%), Positives = 93/310 (30%), Gaps = 45/310 (14%)

Query: 15  VSMIFL-QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
           ++ ++L + G I       ++I K     +  +  +  I++ PG +++   +      G 
Sbjct: 39  MTTLYLTEPGTILRYRNESLIIMKQEKSHNCRLAEITLIVVLPGVQLTDVVISQLLDRGI 98

Query: 74  LLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP---- 129
             +++ + G                 L Q +        + + +K+   +          
Sbjct: 99  ETIFLRQDGQFRGRLQGHFATNMTIRLAQYRTVET-TFGMALAQKLVIGKVRNQRVLLQR 157

Query: 130 ------------------------------ARRSVEQLRGIEGSRVRATYALLAKQYGVT 159
                                            +  +L G+EG   R  Y  L   +   
Sbjct: 158 RNRATNGQISELTEAIDLISVYASQLNNTTTPLNRNELMGVEGICARTYYQALKHWFPTQ 217

Query: 160 WN--GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSF 215
           WN  GR   P      D IN  +S     L     +A + AG  P +GF H       + 
Sbjct: 218 WNFNGRNRRPP----LDPINALLSWGYGVLLARVFSACVQAGLDPYLGFFHAIEPYRPNL 273

Query: 216 VYDIADIIKFDTVVPKAFEIARRNPGEPDREV-RLACRDIFRSSKTLAKLIPLIEDVLAA 274
           V D+ +  +   V      + + +    +          I+  +     L+  +E     
Sbjct: 274 VLDLMEEFRPVVVDQAVISLIQSDLLTQEDFQPSPDGVGIWLGTMGKKLLLGELERRFRT 333

Query: 275 GEIQPPAPPE 284
             + PP   +
Sbjct: 334 SVLYPPQNRQ 343


>UniRef50_Q2LQX3 Uncharacterized protein predicted to be involved in DNA repair n=1
           Tax=Syntrophus aciditrophicus SB RepID=Q2LQX3_SYNAS
          Length = 386

 Score =  173 bits (440), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 45/315 (14%), Positives = 91/315 (28%), Gaps = 37/315 (11%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            +  Q  +I       ++     +   +    +  +++     ++H A+    + G  +V
Sbjct: 4   YVRTQGARIIKEGRHLLVRKGDAVYHTLFTYKLDQLVIFGNVEITHQALAQLMRYGIDVV 63

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP------- 129
           ++   G  +     P          Q  L  +E   L+ VR +   +    A        
Sbjct: 64  FLSFRGRYLGRISPPESKNVFLHKRQYSLLGNETFTLRQVRAIVAGKLANMATLLMRIKR 123

Query: 130 ----------------------ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDP 167
                                    SV+ LRG EG      +    + +        +  
Sbjct: 124 SRNVSLASQKAHEIQSLIRLLFQAESVDSLRGYEGRGSALYFEAFGRGFIENQGF--FRR 181

Query: 168 KDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKF 225
                 D +N  +S   + L     AA+  AG  P  GF+H       S V D+ +  + 
Sbjct: 182 VRRPPTDPVNSVLSLLYTFLMNRVYAAVRVAGLDPYPGFLHALDYGRYSLVLDLMEEFRT 241

Query: 226 DTVVPKAFEIARRNPGEPDRE-VRLACRDIFRSSKTLAKLIPLIED---VLAAGEIQPPA 281
                    +      + +        R+         ++  +  D   ++A G      
Sbjct: 242 IIADTLTLSLFNLKILKREDFYFEEPVREEDFVQDPGERIADVSRDPIGLIANGHGDSEL 301

Query: 282 PPEDAQPVAIPLPVS 296
                Q +A  +PV 
Sbjct: 302 LDLPEQRMAGEMPVE 316


>UniRef50_B9LX94 CRISPR-associated protein Cas1 n=2 Tax=Halobacteriaceae
           RepID=B9LX94_HALLT
          Length = 331

 Score =  173 bits (440), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 41/292 (14%), Positives = 80/292 (27%), Gaps = 36/292 (12%)

Query: 16  SMIFL--QYGQIDVIDGAFVLID---KTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
           S++++  Q  Q+    G   + D     G     P   +  I +  G   S   V  A +
Sbjct: 11  SVVYVTKQGSQVGTEGGRITVWDVDGDEGELASFPTEKLDTINVFGGVNFSTPFVAEANR 70

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP- 129
            G +L +  + G    +        ++    Q  L  DE   + +   M   +       
Sbjct: 71  HGIILNYFTQNGKYRGSFVPEKNTIAEVRRAQYDL--DETAEIDIAADMIAAKIRNARTL 128

Query: 130 --------------------ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD 169
                                  + + LRG+EG      +  L +     W         
Sbjct: 129 LSRKGVHGTELLKDLGVRATTVATKDGLRGVEGEAAERYFNRLDETLTDGWTFE--KRTK 186

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDT 227
               D IN  +S     +     +A+      P +G +H  +    S   D+ +  +   
Sbjct: 187 RPPEDHINSLLSLTYVFMKNEVLSALRQYNLDPFLGVLHADRHGRPSLALDLQEEFRPIF 246

Query: 228 VVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                  +  R     D       +D   +           ++ +      P
Sbjct: 247 CDAFVTRLVNRGVITHDEFT----QDNHLADDAFQTYCSKFDEFMQEEFTHP 294


>UniRef50_UPI000174611D CRISPR-associated protein Cas1/Cas4 n=1 Tax=Verrucomicrobium
           spinosum DSM 4136 RepID=UPI000174611D
          Length = 847

 Score =  173 bits (440), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 49/332 (14%), Positives = 91/332 (27%), Gaps = 62/332 (18%)

Query: 5   PLNPIPLKDRVSMIFL-QYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           P   +  +D    ++L   G  +       V+ D   +     +  +  + +    +++ 
Sbjct: 485 PRRLMAARDDARALYLSTPGYHVGRSGELLVVKDGASLVEEFRINDLTNVAVFGNVQITT 544

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
            AV++  +    L +    G     +           + Q + A D    L + R+    
Sbjct: 545 QAVQVLCEKEIPLAYFSTGGWFYGLTRGHVTKNVFTRIEQFRAADDPMRCLALSRRFVAG 604

Query: 123 RFG-------------------------EPAPARRSVEQLRGIEGSRVRATYALLA---- 153
           +                           + A   RS+E L GIEG+         A    
Sbjct: 605 KIRNHRTLLMRLHVEPPAAVLARLKQASQDALGARSLETLLGIEGAAAALYLQHFAGMIK 664

Query: 154 ------------------------KQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
                                     +   +  R   P      D +N  +S A S L  
Sbjct: 665 VGAADDDDEIPGLESASATRVPEESVFTFDFTKRSRRPP----TDPVNALLSLAYSLLAK 720

Query: 190 VTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREV 247
               A  A G+ P +GF H  +    +   D+ +  +                  PD  V
Sbjct: 721 DCTIAAHAVGFDPYVGFYHQPRYGRPALALDLMEEFRPLVAESVVLTAINNRMLVPDHFV 780

Query: 248 RLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
           R A   +  +S          E  + +    P
Sbjct: 781 R-AGEGVNLTSAGRKVFFQAYEQRMGSIITHP 811


>UniRef50_D0MKP4 CRISPR-associated protein Cas1 n=1 Tax=Rhodothermus marinus DSM
           4252 RepID=D0MKP4_RHOM4
          Length = 525

 Score =  173 bits (438), Expect = 9e-42,   Method: Composition-based stats.
 Identities = 43/318 (13%), Positives = 93/318 (29%), Gaps = 51/318 (16%)

Query: 8   PIPLKDRVSMIFLQY--GQIDVIDGAFVLID----KTGIRTHIPVGSVACIMLEPGTRVS 61
            +P   +   +++      +       V+      +      +P   V  ++L    +++
Sbjct: 178 IMPPVRQARTLYVDEIGAVVRRKGRQLVVTVSRDGRRQELLRVPALLVDQVVLVGPVQIT 237

Query: 62  HAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE 121
             A+R+  +    +V++   G                 L Q +   D +  L + R    
Sbjct: 238 SQALRMLLRRNVDIVYLSGEGRFEGRLAAEFHPHVALRLAQYEAFRDPERTLTLARLFVR 297

Query: 122 LRFG-----------------------------EPAPARRSVEQLRGIEGSRVRATYALL 152
            +                               E      ++E LRG+EG+  R  +++ 
Sbjct: 298 GKLQNMAGLLRRYADEYGSASLRAAASEINRDLERLEQVTTLEALRGVEGTASRRYFSVF 357

Query: 153 AKQY---------GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPA 203
            +              + GR   P      D +N  +    + L G   AA   AG  P 
Sbjct: 358 GEMLRAEAYAPTGWPAFPGRHRRPP----TDPVNATLGYLYALLLGNVVAACALAGLDPY 413

Query: 204 IGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTL 261
           +G++H       S   D+ +  +       A  +  R    P +        ++ +    
Sbjct: 414 VGYLHAPAYGRPSLALDLMEEFRAPAADRLALRLFNRGRLRP-QHFEERNGGVYLNEAGR 472

Query: 262 AKLIPLIEDVLAAGEIQP 279
           A ++   +         P
Sbjct: 473 AVVLEAWQAHRQQTSAHP 490


>UniRef50_D2LF35 CRISPR-associated protein Cas1 n=1 Tax=Rhodomicrobium vannielii
           ATCC 17100 RepID=D2LF35_RHOVA
          Length = 366

 Score =  172 bits (437), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 48/283 (16%), Positives = 80/283 (28%), Gaps = 37/283 (13%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
             + V +   ++          P+  V+ + +    RV+ A +      G  +VW G  G
Sbjct: 50  AVVRVNNSTLLVERPGEPVFERPIELVSTLHIHGWARVTGACIGRLTAQGATVVWRGLHG 109

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA-------------- 128
             V  +    GA  D    Q   A  E   L + R +   +                   
Sbjct: 110 YPVALAQPMHGAGLDIRRAQYFEAAGERG-LAIARALISAKIQNMRGLVRRRANIEGRDC 168

Query: 129 ----------PARRSVEQLRGIEGSRVRATYALLAKQY-----GVTWNGRRYDPKDWEKG 173
                         S E L GIEGS     ++     +      V +  R   P      
Sbjct: 169 LTALAALAKKAKHASRESLLGIEGSATAFYFSAWPHMFAARAGDVEFEVRSRRPPQ---- 224

Query: 174 DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPK 231
           + +N  +S A + L      A+ A G  P +G  H  +    S   D+ +  +       
Sbjct: 225 NAVNATLSYAYAVLSAECVCALAAVGLDPRLGVFHQPRSGRASLALDLMEPFRPLIADQA 284

Query: 232 AFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
                         +   A             +I L+E  L  
Sbjct: 285 VLTGFNTGQIRTG-DAAEADDGWRLGETGKRTVIDLMEKRLTT 326


>UniRef50_C7NA04 CRISPR-associated protein Cas1 n=1 Tax=Leptotrichia buccalis
           C-1013-b RepID=C7NA04_LEPBD
          Length = 323

 Score =  171 bits (434), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 36/297 (12%), Positives = 85/297 (28%), Gaps = 43/297 (14%)

Query: 18  IFLQY-GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
           +++   G +         I  +  +  +    +  ++L  G  ++   ++LA      +V
Sbjct: 3   LYITDLGTVVKKRDDLFEITTSEKKVAVAPQKIKSLVLSKGIFLTTDVIKLAVDNNIDIV 62

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVE- 135
            V + G       Q     +  +  +          +++ +++   +    A     ++ 
Sbjct: 63  IVDDFGNPYGRFWQSKFGSTANIRRKQLEIFGTQKGIELAKQILIQKIKNCAEHLEDLKI 122

Query: 136 -----------------------------------QLRGIEGSRVRATYALLAKQYGVTW 160
                                               L G EG+  +  Y  L++     +
Sbjct: 123 KREAKKAFLDKQIKEMKRYIYQIKLVEGNVSEKRGTLMGYEGNAAKIYYQTLSELIPEGF 182

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYD 218
                        D  N  ++ A   LY   E A + AG  P +G +HT      S V+D
Sbjct: 183 KFE--KRSMHPAEDEFNAMLNYAFGILYSKVEKACIIAGLDPYVGIIHTDNYGKKSLVFD 240

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
           + +  +        F +  +   +     +     +         L+    + L   
Sbjct: 241 LIESYR-HLASRTVFSLFTQKRVQ-KYFFKREGNSVMLVGDGKKVLVESFYNRLEKK 295


>UniRef50_A1BI46 CRISPR-associated protein Cas1 n=2 Tax=Chlorobiaceae
           RepID=A1BI46_CHLPD
          Length = 347

 Score =  171 bits (434), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 45/308 (14%), Positives = 91/308 (29%), Gaps = 50/308 (16%)

Query: 17  MIFLQY--GQIDVIDGAFVLIDKTG----IRTHIPVGSVACIMLEPGTRVSHAAVRLAAQ 70
            +++Q     + V +G F +             +    V  I+L     ++ AA+R    
Sbjct: 10  TLYIQEQGSMLRVENGCFRVTCGHDDDVAELLEVQSIKVGQIVLFGACMITPAAIRHCLM 69

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR------- 123
               +V + + G              D    Q + + +E   L+  R +   +       
Sbjct: 70  NRIPVVLLSQHGEYFTRLESTDDVNIDLERLQFQRSAEESFPLECSRTIVRAKLHNSGVL 129

Query: 124 ----------------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQY---GV 158
                                   E      S++ +RG EGS     + +    +   G 
Sbjct: 130 LRRHAESSGSEALRHAATQLRQLEEHVDRADSIDAVRGYEGSGAATYFGVFEDFFDTGGF 189

Query: 159 TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKP--LSFV 216
            +  R   P      D +N  +S   S L+    +        P +GF+H  KP   + V
Sbjct: 190 IFRERVKRPP----TDPVNAMLSFGYSLLFNNIFSMARLHRLHPYVGFLHADKPAHPALV 245

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREV-----RLACRDIFRSSKTLAKLIPLIEDV 271
            D+ +  +   V      +  +    P+            +  + S       +   E++
Sbjct: 246 SDLIEEFRT-LVDGLVIALINKRLISPEEFTVARHDDGKPKGCYLSDGARKTFLREFENL 304

Query: 272 LAAGEIQP 279
           +      P
Sbjct: 305 MHRTTTHP 312


>UniRef50_A9AX66 CRISPR-associated protein Cas1 n=1 Tax=Herpetosiphon aurantiacus
           ATCC 23779 RepID=A9AX66_HERA2
          Length = 350

 Score =  171 bits (434), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 35/317 (11%), Positives = 83/317 (26%), Gaps = 55/317 (17%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGI-------RTHIPVGSVACIMLEPGTRVSHAAV 65
           +  ++L  QY  +     A  +                +P+  +  ++++    ++ +A+
Sbjct: 1   MQTLYLSEQYSIVKREGEALRVEIPEDQQLGRQRQVVRVPLNVIERVVVQGEITLTASAL 60

Query: 66  RLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF----- 120
               +      ++  +G    A        +   L Q         R  + R        
Sbjct: 61  ACLLERRICTHFLSYSGRSQGALTPDPTRNASLRLAQYAAHTSIQHRFSLARTFVDGKLR 120

Query: 121 -----------------------ELRFGEPAPARRSVEQ-------------LRGIEGSR 144
                                   LR         S+ +             + G EG  
Sbjct: 121 NLRTQILRFNRSQREPTLTQAIERLRDAHRDLHGLSIPEYVDPLDRMHGMGQILGCEGQG 180

Query: 145 VRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAI 204
             A +          W    +  +     D +N  +S     L     + +   G+ P I
Sbjct: 181 SAAYWDCWGMLLNQPWE--WHGRRRRPPPDPVNALLSYGYVILTSQVLSQLAIVGFDPYI 238

Query: 205 GFVHTGK--PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLA 262
           GF+H       +   D+ +  +   V      +         +  +     +  S +   
Sbjct: 239 GFLHQSSFGKPALALDLMEEFRPVIVDSVVLTVLNTKILN-QQHFQREPGSVQLSKEGRK 297

Query: 263 KLIPLIEDVLAAGEIQP 279
             +  +E+  ++    P
Sbjct: 298 LFLTKLEERFSSEIQHP 314


>UniRef50_Q2J7N9 CRISPR-associated protein Cas1 n=1 Tax=Frankia sp. CcI3
           RepID=Q2J7N9_FRASC
          Length = 344

 Score =  171 bits (433), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 41/303 (13%), Positives = 81/303 (26%), Gaps = 47/303 (15%)

Query: 11  LKDRVSMIF-LQYGQ-IDVIDGAFVLI--DKTGIRTHIPVGSVACIMLEPGTRVSHAAVR 66
           + + ++ ++    G  + +   A  +   D    R  +P+  V  I++  G  ++   ++
Sbjct: 1   MAELLNTLYATTPGTSLHLDGDAVRIWHPDNDKGRRLLPLVRVDHIVVFGGVTITDDLLQ 60

Query: 67  LAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
             A     + W+   G        P G      + Q     D++ RL +       +   
Sbjct: 61  RCATDRRSVTWLTGNGRFRARVEGPTGGNPHLRIAQHDHFRDDERRLTLAMSYIAGKLQN 120

Query: 127 PAP--------------------------------ARRSVEQLRGIEGSRVRATYALLAK 154
                                                 +V +  G+EG   R   A    
Sbjct: 121 SRQLLLRAARDATGTRQTALRDTAAHLADALPTLRDTTNVAEAMGVEGQAARRYIATWPH 180

Query: 155 QYGVTWN-----GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
                       GR   P      D +N  +S     L      A+   G  P IG++H 
Sbjct: 181 LLTPHATVTAPAGRTSRP----ATDPVNAALSFGYGILRIAVHGALDHVGLDPHIGYLHG 236

Query: 210 GKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPL 267
            +P   +   D+ +  +   V    F    +                  +       + L
Sbjct: 237 IRPGKPALALDLMEEFRALLVDRLVFTAFNQRQLTDADFEHHPGGSCQLTESGRKNYLTL 296

Query: 268 IED 270
              
Sbjct: 297 WSQ 299


>UniRef50_A9GDF7 Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So
           ce 56' RepID=A9GDF7_SORC5
          Length = 365

 Score =  170 bits (432), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 54/304 (17%), Positives = 101/304 (33%), Gaps = 38/304 (12%)

Query: 5   PLNPIPL-KDRVSMIFLQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSH 62
           P+   P   +R S+  + +G +I     AF + ++ G RT I    V+ I++    +++ 
Sbjct: 19  PVRLYPPDTERRSLHVVSHGARIGRASDAFEVTEREGERTRIGAREVSDIVVHGHAQITT 78

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
            A+RL A     + +VG  G  V      G +   + + Q +   D+   + + R++   
Sbjct: 79  QALRLCAAEEIAVHFVGAGGAHVGVFS-GGSSGVQRRIRQFRGLTDDVFAIGLARRLVMA 137

Query: 123 RFGEPAPA-------------------------------RRSVEQLRGIEGSRVRATYAL 151
           +                                            L G EG+  R  +  
Sbjct: 138 KIEMQLRHVLRASRKDEALRAGLDEPIESLRGGLRRAAKAADRTSLMGQEGNAARGYFGA 197

Query: 152 LAKQYGVTWNG--RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT 209
           LA           R          D  N  +S   + LY    +AIL  G  P  G +H 
Sbjct: 198 LAALVHPDAGDALRPRGRSRRPPEDRFNALLSFGYTLLYRDVLSAILRVGLEPGFGVLHQ 257

Query: 210 GKPLS--FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPL 267
            +  +     D+ ++ +   V         R   + +R+  +  R ++ S       I +
Sbjct: 258 PRSAAFPLALDLTELFRVPVVDMAVLGAVNRRTFDAERDFVITGRQVWLSDAGHRAFIEV 317

Query: 268 IEDV 271
            E  
Sbjct: 318 YERR 321


>UniRef50_B3EG05 CRISPR-associated protein Cas1 n=11 Tax=Bacteria RepID=B3EG05_CHLL2
          Length = 384

 Score =  170 bits (432), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 37/334 (11%), Positives = 92/334 (27%), Gaps = 68/334 (20%)

Query: 8   PIPLKDRVSMI-FLQYGQIDVIDGAFVLIDKTGIRTH-----------------IPVGSV 49
            +  ++ +S + ++   +I V     + ++      +                 IP+ ++
Sbjct: 19  LLRKENTISFVPYVTQDEITVETNPSLYLEPDEEEAYSLNPVKDEHLNTAARRVIPINNI 78

Query: 50  ACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALD 108
               +      +   +    +    L      G    +   +        ++ Q K    
Sbjct: 79  DSFFVFGEVSFNTKFLNFLTRNRIPLHLFNYYGFYSGSYYPREHLLSGYLVVNQVKHYSS 138

Query: 109 EDLRLKVVRKMFELR-------------------------------------FGEPAPAR 131
              RL++ R+                                                A 
Sbjct: 139 TKKRLEIAREFIGAAAANIIRNLKYYTADSRQGVQDDESLAMLFHTIAQIESLANGIAAA 198

Query: 132 RSVEQLRGIEGSRVRATYALLAKQYG-----VTWNGRRYDPKDWEKGDTINQCISAATSC 186
           + +  L G+EG+  +  Y +  +         +++ R   P D    + +N  +S   S 
Sbjct: 199 QDIPSLMGVEGNIRKVYYQVWQQLLRSADPAFSFSERVKRPPD----NAVNALVSFGNSL 254

Query: 187 LYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
           +Y      I      P + F+H    +  S   D+A++ K   +    F++      +  
Sbjct: 255 MYSACLTEIYRTQLNPTVSFLHEPSERRFSLALDMAEVFKPMFIDRLIFKLVNTRAIQA- 313

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           R    A      +      ++   E+ +      
Sbjct: 314 RHFTTALNFCHLNDAGRKIVVKEFEERMRTTIKH 347


>UniRef50_Q0ADY5 CRISPR-associated protein, Cas1 family n=2 Tax=Nitrosomonas
           RepID=Q0ADY5_NITEC
          Length = 328

 Score =  170 bits (430), Expect = 7e-41,   Method: Composition-based stats.
 Identities = 42/291 (14%), Positives = 90/291 (30%), Gaps = 43/291 (14%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           ++ +F+      +++  GA V  +       +P+  +  + L    ++  A +    + G
Sbjct: 1   MTSLFVDRRGVVLELESGAIVFRENGERIGTVPIAPLTRVFLRGDVKLPAALLGKLGEQG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP--- 129
             +V +     R           + + + Q +L+ D+   L++ + + E +         
Sbjct: 61  VGVVILSGRIGRPSLLLARPHNDAARRVVQIRLSFDKPFCLQIAKALIERKLTRQIEWFA 120

Query: 130 ----------------------------ARRSVEQLRGIEGSRVRATYALLAKQYG--VT 159
                                          S   LRG+EGS     ++ L       + 
Sbjct: 121 ELRENDMQVRYELSHALRALEEHRSRIGHVSSAASLRGVEGSAAARYFSGLQAVVPDSLH 180

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVY 217
           ++GR   P      D  N  +S   + L+     A+   G+ P +GF H       S   
Sbjct: 181 FSGRNRRPPR----DPFNALLSLTYTLLHSEIAIALYGTGFDPYVGFYHRLAFGRESLAS 236

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
           D+ + ++       A  + R+   E D                  +     
Sbjct: 237 DLLEPLRP-LADQFALALIRKKVLEKD-HFSTTEAGCLLGKAGRTRYYAAY 285


>UniRef50_Q2FL78 CRISPR-associated protein, Cas1 family n=1 Tax=Methanospirillum
           hungatei JF-1 RepID=Q2FL78_METHJ
          Length = 331

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 51/308 (16%), Positives = 98/308 (31%), Gaps = 40/308 (12%)

Query: 15  VSMIFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSV-----ACIMLEPGTRVSHAAVRL 67
           ++ + +     +I        +       T  P  ++       + +     +S AAVRL
Sbjct: 1   MNSVLITGAGYRIRKRGDVLTIETGKDSDTAEPPRTLSPLGLDLLAIAGDHSISTAAVRL 60

Query: 68  AAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM-------- 119
               G  +  +   G   +    P G  +    Y+A+ +  E+ RL++ R +        
Sbjct: 61  VTSHGGAIALMDGLGNP-FGHFLPLGRSALIEQYEAQASAPEERRLEIARSICTGALENK 119

Query: 120 ----------------FELRF----GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVT 159
                            E+R      + A   +S++ LRG+EGS   A +   +  +   
Sbjct: 120 RTLLSNLERIRGFDLSREIRLVEDAQDKALECQSLDSLRGVEGSGAHAYFQGFSLAFDEE 179

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVY 217
           W             D +N  +S     LY     A++ +GY+P  G  H    K  + VY
Sbjct: 180 WGFLG--RSQNPATDPVNSLLSYGYGMLYIQARQALVLSGYSPYYGAYHETYKKQEALVY 237

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           D+ +  +   V         ++   PD             +    K    +   +     
Sbjct: 238 DLVEEFRQPVVDRTVVTFLAKHMATPDDFTYPDEGGCMIGTMAKKKYAAAVLTRIHGKVK 297

Query: 278 QPPAPPED 285
                 +D
Sbjct: 298 YEEQTFQD 305


>UniRef50_B8CYA1 CRISPR-associated protein Cas1 n=2 Tax=cellular organisms
           RepID=B8CYA1_HALOH
          Length = 325

 Score =  169 bits (428), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 53/294 (18%), Positives = 97/294 (32%), Gaps = 48/294 (16%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
             + V   +F +  +   +  +    V+ I++  G  +S  AV+LA +    + ++ E G
Sbjct: 10  SYLHVKQKSFEIKTEEDKK-RVSAKKVSSILITTGAAISTDAVKLALENNIEIQFLDEFG 68

Query: 83  VRVYASGQPGGARSDKLLY-QAKLALDED-------------------------LRLKVV 116
             +     P    +  +   Q +LA  E+                          R K  
Sbjct: 69  CSLGKVWHPKLGSTTYIRRKQLELAESEEGTELVKEFMLDKIDNMINHLHDLAIKRSKSK 128

Query: 117 RKMFELRFGEPAPARRSVE-----------QLRGIEGSRVRATYALLAKQYG--VTWNGR 163
            K    +  E    R  +E            + G EG+  R  +A L+        +NGR
Sbjct: 129 EKYINKKIKEICELRNKLEKVTGYIEDVRNTIMGYEGNISRKYFASLSFLLPDRYKFNGR 188

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIAD 221
            + P      D  N  ++     LYG  E A++ AG  P +G +HT      SFV+D  +
Sbjct: 189 SFRP----AEDEFNCLLNYGYGVLYGKVEKALIIAGLDPYVGILHTDGYNKKSFVFDFIE 244

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
             +         ++  R               +  + +    L+  + D     
Sbjct: 245 PYRHHI-DRVVMKLFSRKKIR-KLHFDKIQGGLTLNDEGKKLLLTELNDYFDKK 296


>UniRef50_A0LHZ4 CRISPR-associated protein, Cas1 family n=2 Tax=Deltaproteobacteria
           RepID=A0LHZ4_SYNFM
          Length = 350

 Score =  168 bits (427), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 48/315 (15%), Positives = 90/315 (28%), Gaps = 54/315 (17%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           + I  Q   +       V+     I   IP+  ++ + L   + +S A + +  +     
Sbjct: 4   TYILEQGAYLRKAGNHLVVTKNREIIAEIPLEGLSQLTLVGFSSLSGAVLEVLIRHRIET 63

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE--------- 126
           V +   G               +   Q       D  L+  + +   +            
Sbjct: 64  VLLSPRGQFRARLMVDEHKHVQRRQGQYVKLSGADFALRTTQSIVRGKLRNTARFLALRG 123

Query: 127 --------------------PAPARRSVEQLRGIEGSRVRATYALL---AKQYGVTWNGR 163
                                   ++ ++ LRGIEG      + +     +  G  +NGR
Sbjct: 124 SRYGSEALHRAAAQIKGLSALVDRQKDMDLLRGIEGHAANLYFEVFPLLVRVPGFEFNGR 183

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVYDIA 220
              P      D +N  +S   + L      AI   G  P +G +H    G+P S   D+ 
Sbjct: 184 NRRPP----LDPLNALLSFVYTLLTQEVLTAIKVVGLDPYLGCLHAVDYGRP-SLACDLV 238

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRL--ACRDIFRSSKTLAK------------LIP 266
           +  +          +  R     D  V     C D     +   +             I 
Sbjct: 239 EEWRTFLGDRLVLALVNRRVIGLDDFVYRPTPCADAVDEEELKHRRPVEMKPKIARAFIE 298

Query: 267 LIEDVLAAGEIQPPA 281
             E  +A+  + P +
Sbjct: 299 AYEKWMASRILDPGS 313


>UniRef50_B0TFX3 Crispr-associated protein cas1 n=4 Tax=Clostridia
           RepID=B0TFX3_HELMI
          Length = 364

 Score =  168 bits (427), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 49/300 (16%), Positives = 94/300 (31%), Gaps = 57/300 (19%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACI-MLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
             +    G  V+ +K  + T +P   V  + ++  G  +S  A+    + G  +  +   
Sbjct: 39  ASLGKKSGRLVVREKGQVVTEVPFDRVEQVTVITSGASLSTDAIEECVRHGIEINLLDFR 98

Query: 82  GVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA----------- 130
           G        PG   + K   +  LA ++   + + +     +                  
Sbjct: 99  GSPYAKLFAPGLTATVKTRREQLLAFNDQRSIFLAKAFVRGKIQNQINTLKYFAKYRKSA 158

Query: 131 ---------------RRSVEQLRGI---------------EGSRVRATYALLAKQYG--V 158
                           +++++L GI               EG      +  +A      V
Sbjct: 159 RQEVYAYLQDAALLMEKNLQELTGIDGLNIDAVRGPLMSVEGRAATRYWDAVAFLLKGYV 218

Query: 159 TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFV 216
            + GR     +    D +N  ++   + L      A+L AG  P  GF+H  +P   S V
Sbjct: 219 VFPGRE----NRGATDPVNSLLNYGYAVLEARVLGAVLQAGLDPYAGFLHVDRPGKTSLV 274

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGE 276
           YD  +  +   +      +           V +       +  T   L+  I+  LAA E
Sbjct: 275 YDFIEEFRQPVIDRPVLAMVIAG-------VEIGMEGERLADGTKRDLLERIQQRLAATE 327


>UniRef50_C8WTR3 CRISPR-associated protein Cas1 n=2 Tax=Alicyclobacillus
           acidocaldarius RepID=C8WTR3_ALIAD
          Length = 346

 Score =  168 bits (426), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 47/306 (15%), Positives = 94/306 (30%), Gaps = 47/306 (15%)

Query: 17  MIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
            +F+Q     + V     V+  +      +P+  V  I+       +   +   A  G  
Sbjct: 8   TLFVQREGAIVRVHQDTVVVTLENETLLRVPMHMVDSIVGIGRVSFTSPLLERCAAEGRS 67

Query: 75  LVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP------- 127
           +V +   G  +Y               Q + A   +  L ++R +   +           
Sbjct: 68  VVRMTRGGRFLYRIEGRMSGNVLLRTAQHEAARSPERSLTIMRAIVAGKVHNQRQLVLKA 127

Query: 128 --------------------------APARRSVEQLRGIEGSRVRATYALLAKQYG---- 157
                                      P+    +++RG+EG+  R  +  L         
Sbjct: 128 ARDLTAPADRSFVREVAGDLGRELRKLPSASHPDEIRGVEGASARRYFMALRHLIAPAIR 187

Query: 158 --VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL-- 213
             ++++GR   P      D +N  +S   + +    E+A+L  G  P IGF+HT +P   
Sbjct: 188 DALSFDGRNRRPPR----DPVNAVLSFLYALITRDAESALLGVGLDPQIGFLHTLRPGRP 243

Query: 214 SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
           S   D+ + ++          +  R   +P     L    +  +      L    +    
Sbjct: 244 SLALDLVEEMRPILADRVMLSLFNRRQLQPSDFEVLPGGAVELTDSGRRTLFAEWDRRKQ 303

Query: 274 AGEIQP 279
                P
Sbjct: 304 VEIEHP 309


>UniRef50_A7GY67 Crispr-associated protein Cas1 n=6 Tax=Campylobacter
           RepID=A7GY67_CAMC5
          Length = 332

 Score =  166 bits (421), Expect = 7e-40,   Method: Composition-based stats.
 Identities = 51/295 (17%), Positives = 88/295 (29%), Gaps = 34/295 (11%)

Query: 12  KDRVSMIFLQYGQIDVIDGAFVLIDKTGI-----RTHIPVGSVACIMLEPGTRVSHAAVR 66
            DR   I L  G++   D                   +P+ ++  I +     +    + 
Sbjct: 4   SDRTHFI-LSSGRLRRQDNNIYFDKFDETGGVTASKILPINAIDEIYILTRVELDTYTLA 62

Query: 67  LAAQVGTLLV----WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
             A    LL     +    G    ++          LL Q +   D   R+ + R++   
Sbjct: 63  FLADNNILLHVFSPFQSFRGNFYPSTSNSVNKSGFALLSQLRAFDDPVKRVYIAREITRA 122

Query: 123 RFGEP-------------------APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGR 163
                                     A   V Q+   EG+  +  Y    +      + +
Sbjct: 123 HMLNDAANCKKHGVKFDPAPHIAALDAAADVGQIMAAEGAFQKLYYEKWNEIIADQRSFK 182

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIAD 221
                     D IN  IS   + +Y V  + I      P IGF+H    + LS   D+A+
Sbjct: 183 FTVRSKRPPADKINSFISYVNTRIYNVCLSEIYKTELDPRIGFLHEPNYRALSLHLDLAE 242

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSS---KTLAKLIPLIEDVLA 273
           I K        F +  +           A R  F +    K   K+I  + + +A
Sbjct: 243 IFKPILGDTLIFAMLNKKEITAKDFQTDAGRIKFSNDAIQKIEMKMISRLSETIA 297


>UniRef50_Q96X75 Putative uncharacterized protein ST2634 n=1 Tax=Sulfolobus tokodaii
           RepID=Q96X75_SULTO
          Length = 317

 Score =  165 bits (419), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 46/276 (16%), Positives = 92/276 (33%), Gaps = 34/276 (12%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           ++      FV+  K G + ++    V  I++   G  V+  A+RLA   G  ++++   G
Sbjct: 25  KLSTKGKTFVISKKDGKKVNVSPAEVDQIVIMTSGVTVTSKAIRLALDHGIDIIFLDSRG 84

Query: 83  VRVYASGQPGG-ARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIE 141
                          +    Q    L  +   ++ R++ + +    A   +   +  GIE
Sbjct: 85  NPFGRLFHSEPIKTVETRKAQYLAILKGEE--EIPREIIKSKIKNQANHIKFWFKKLGIE 142

Query: 142 GS--------------RVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCL 187
           G+                R  +  L +   +   GR     D E  D  N   + A + L
Sbjct: 143 GNDYKLIEGKDDDEATAARYYWHALGRI--IPMKGR-----DPESTDPFNVSFNYAYAIL 195

Query: 188 YGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDR 245
           Y   +  +   G  P  GF+H  +    S VYD +++ K   V      +          
Sbjct: 196 YSNIQRVLQLVGLDPYAGFIHKDRSGKPSLVYDFSEMFKPVLVDYPLVSLFINGFIPN-- 253

Query: 246 EVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPA 281
                 +D    +++  K+   + + +         
Sbjct: 254 -----VKDGILDAESRKKIAEAVINAMNGKVKDEGG 284


>UniRef50_A8UXX8 Putative uncharacterized protein n=1 Tax=Hydrogenivirga sp.
           128-5-R1-1 RepID=A8UXX8_9AQUI
          Length = 290

 Score =  165 bits (418), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 45/277 (16%), Positives = 100/277 (36%), Gaps = 30/277 (10%)

Query: 13  DRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
            R+ +++    ++        +   + I + +PV  V  I+   G  +S  A+ L  Q  
Sbjct: 2   KRIVVVY-SSARVSRSGERVKISTFS-INSSLPVRYVEAIVAFGGLELSSHALSLLMQNN 59

Query: 73  TLLVWVGEAGVRVYASG-QPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP---- 127
             + ++ + G        +   + +   + Q +  + +     V +++   +        
Sbjct: 60  VPVFFLTKLGALKAVLWTKILSSNTSNRIRQYEKYVRDPF--GVAKEIVRAKIRTIEREF 117

Query: 128 ----------APARRSVEQLRGIEGSRVRATYALLAKQY---GVTWNGRRYDPKDWEKGD 174
                          + E+L GIEG+  R  +   ++     G ++  R Y P      D
Sbjct: 118 GLKLNNLISSLERAGTKEELLGIEGTASRLMFERFSQNIELSGFSFRERAYHPPP----D 173

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPKA 232
            +N  +S + +  Y ++       GY P I F+HT  G  L+   DI + ++        
Sbjct: 174 PVNALLSLSYTFTYALSLPLTTLMGYDPYISFLHTRSGSHLALCSDIMEPVRPVLTKRLE 233

Query: 233 FEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIE 269
             I RR   +  ++        +   +++ K +   E
Sbjct: 234 EPILRRVFTK--KDFNRERAACYLKKESMPKFLNWFE 268


>UniRef50_D0W646 CRISPR-associated protein Cas1 n=1 Tax=Neisseria cinerea ATCC 14685
           RepID=D0W646_NEICI
          Length = 325

 Score =  165 bits (418), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 37/293 (12%), Positives = 83/293 (28%), Gaps = 43/293 (14%)

Query: 15  VSMIFLQYGQIDV--IDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           ++ +++    + +     + V  +       IP+  + C+ +     +S   +    +  
Sbjct: 1   MTTLYIDRKNLTLRADGDSLVCYENGERTATIPLKVLQCVCIRGDLTLSAKVLGKLGEAD 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL---------- 122
             ++ +     R             + + Q   + D+   L   R               
Sbjct: 61  IGVLVLNGRLKRPALMLPNLKLDGSRRVAQYAFSQDKAACLAAARNTVSAKLSAQQQHLQ 120

Query: 123 ---------------------RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG--VT 159
                                R  +  P    + +LRGIEG+     +   A      + 
Sbjct: 121 QMMPSDGTAADCLNKHIKAISRLADTVPDCNGIARLRGIEGAAAAQYFGAWAAVLPETLH 180

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVY 217
           + GR   P      D +N  +S   + ++      +  +G  P IG+ H  +    S   
Sbjct: 181 FTGRNRRPPR----DPVNAALSLTYTLMHFEIVKHLHLSGLDPFIGYYHLPEHGRESLAC 236

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
           D+ + ++          +  R    P  +     +          K  P  E 
Sbjct: 237 DLTEHLRCR-CDEWVLSLFARQILTP-SDFSTNPQGCLMGKNARIKFYPAYEQ 287


>UniRef50_A4FXZ8 CRISPR-associated protein, Cas1 family n=9 Tax=cellular organisms
           RepID=A4FXZ8_METM5
          Length = 342

 Score =  165 bits (418), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 50/296 (16%), Positives = 94/296 (31%), Gaps = 50/296 (16%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV 83
            I      F L         IP   V  I++   + +S  A+ LA +    LV +   G 
Sbjct: 27  YISKSGTRFKL-KNGENVQEIPAKKVEQILITCPSSISTEAISLAVEENIDLVLLKMNGK 85

Query: 84  RVYASGQPGGARSDKLLYQAKLALDEDLRL-----KVVRKMFE----------------- 121
            +             +  +  L  + +L +      + +KM                   
Sbjct: 86  PIGRFWHSKHGSISTIRKKQLLLSENELGITFVKEWISKKMENQIDFLKMLSMNRRDERR 145

Query: 122 -------LRFGEPAPA------RRSVEQLR----GIEGSRVRATYALLAKQYG--VTWNG 162
                  L+  E           ++++++R    G EG   R  + +++K       +NG
Sbjct: 146 ELLKENVLKIDEEIKKLDNVTFNQNIDEIRNTVQGYEGYASRVYFEMISKSLPEKYQFNG 205

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIA 220
           R  +P      D  N  ++     LY   E + + AG  P IG +H       +F +D+ 
Sbjct: 206 RSRNPAK----DYFNCMLNYGYGILYSQIERSCIIAGLDPYIGILHVDNYNRKAFTFDLI 261

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGE 276
           +  +   V    F++        D          F +      LI     ++ + E
Sbjct: 262 EKYR-IYVDKTIFKMFSTKKIR-DDFFEEIEGGFFLAKDGKQALISEYNLLMESTE 315


>UniRef50_B5YJS2 Crispr-associated protein Cas1 n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YJS2_THEYD
          Length = 318

 Score =  164 bits (416), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 42/294 (14%), Positives = 92/294 (31%), Gaps = 43/294 (14%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +F+     +I V   +     K      +P+  +  +++    ++  + +      G
Sbjct: 1   MSTVFIDRKDIEIRVDGNSISFYAKGKKDGSLPLSPLKRVVIVGNVKIETSVLYKLVNHG 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF-------- 124
             ++++            P        + Q + +L     LK  +++ + +         
Sbjct: 61  ITVLFLTGKLKYSGILNGPLHNNGLLRVKQYQKSLS-GFSLKFAKELIKRKIVSQRDFLS 119

Query: 125 ------------------------GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTW 160
                                           S++ LRGIEG+     +   +K +  + 
Sbjct: 120 EIREIKKALAMQADRAIEILNKAISNIEVTPISIDSLRGIEGAASSIYFITYSKIFPNSL 179

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT---GKPLSFVY 217
                        D +N  +S   + L+      I   G  P IGF H    G+  S   
Sbjct: 180 KF--VRRIKRPPKDPVNAMLSLCYTLLHYEIVREIQLIGLDPTIGFYHQFEYGRE-SLAC 236

Query: 218 DIADIIKFDTVVPKAFEIA-RRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
           D+ ++ + + V    +E+   ++ G  D         ++       K  PL E 
Sbjct: 237 DLVELFRVN-VDRFVYELFKAKHLGNRDFMKDEESGGVYLKKTGRKKFYPLYEQ 289


>UniRef50_B0VHC1 Putative uncharacterized protein n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VHC1_9BACT
          Length = 344

 Score =  164 bits (415), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 33/310 (10%), Positives = 79/310 (25%), Gaps = 54/310 (17%)

Query: 15  VSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           + ++++  Q   I        +     +        +  ++L     ++   V    +  
Sbjct: 1   MPVVYIADQGSHICKKGDRLYVYRGNQLLRWFHTKDIIQLILVGNIGLTSQVVTYLLKNR 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARR 132
              V++   G          G      + Q +   + + R+ +   +   +         
Sbjct: 61  IDTVFLSYYGKFKGRLVGEFGKNVMLRVNQFQYLNEPENRVYLANLIIRGKIENSLLHLA 120

Query: 133 SV------------------------------EQLRGIEGSRVRATYALLAKQY---GVT 159
                                           + L G EG   +  +A            
Sbjct: 121 KRKKRNKAESLTFAYIKNKALLAQLKTQILPKDILLGYEGIAAKNYFAAFPDLIANPDFP 180

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVY 217
           ++GR   P      D +N  +S + + L      A    G  P  G +H       S V 
Sbjct: 181 FSGRNKRPPK----DEVNAMLSLSYTFLMNQVMCAAYICGLDPYYGALHDLDYGRQSLVL 236

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRD------------IFRSSKTLAKLI 265
           DI +  +   +      +  R     +  +     D            +  +   +  +I
Sbjct: 237 DIMEEFRP-LIDNMVISLINRKEIRLEHFLYNTLPDDENSDLDNSTLPVSLTKNGMKIII 295

Query: 266 PLIEDVLAAG 275
                ++ + 
Sbjct: 296 TAFSKLINSK 305


>UniRef50_A7NP58 CRISPR-associated protein Cas1 n=6 Tax=Chloroflexi (class)
           RepID=A7NP58_ROSCS
          Length = 338

 Score =  163 bits (412), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 45/302 (14%), Positives = 87/302 (28%), Gaps = 57/302 (18%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVGTLLVWVGE-AG 82
           I    G   ++ +    + +P+  +  I++   G  +S   VR  A+ G  + ++    G
Sbjct: 12  ISKHQGRIRVMKEKERLSEVPIMHLEQILICSDGVGLSSDVVRACAEEGIPIHFLNSANG 71

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM-------------FELRFGEPAP 129
                    G             A D++  L++ +               +  +  +   
Sbjct: 72  GDYGTFVHSGITGMALTRRAQLRAGDDERGLRLAQAFASGKIQSQANMLRYAAKNRKEND 131

Query: 130 ARR----------------------------SVEQLRGIEGSRVRATYALLAKQYGVT-- 159
                                          +   L G EG      +  +A+       
Sbjct: 132 PDLHNDLMRTATEILDALPPLRAVRGVLTDETRAALMGFEGMAGARYWTAVARIIPDDLG 191

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVY 217
           W GR          D  NQ ++     L      A++ AG  P  GF+H  +P   S   
Sbjct: 192 WPGRETR----GARDRFNQALNYGYGVLQSQVRTALILAGLDPNAGFLHADRPGKPSLTL 247

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           D+ +  +   V      +  R      R+      D      T  ++   I + L + E+
Sbjct: 248 DLIEEFRQAVVDRTLIGLVNRQFEIVQRD------DGLLDEDTRKRIAEKILERLNSTEL 301

Query: 278 QP 279
             
Sbjct: 302 YE 303


>UniRef50_A7BYC5 Protein containing DUF48 n=1 Tax=Beggiatoa sp. PS
           RepID=A7BYC5_9GAMM
          Length = 322

 Score =  163 bits (412), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 45/308 (14%), Positives = 89/308 (28%), Gaps = 39/308 (12%)

Query: 15  VSMIFLQY-GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
           +  +F+     +   +    +    G     P+  +  ++L   + ++   + L  Q G 
Sbjct: 1   METLFISRDATLKRRENTLAVTV-GGKTKPFPIEKIRHLVLLGESSLNTKLLTLCGQNGV 59

Query: 74  LLVWVGEAGVRVYASGQPG-GARSDKLLYQAKLALDEDLRLKVVR--------------K 118
            L      G    A             L QAKL LD++ R+ + R               
Sbjct: 60  RLSIFDYYGYFKGAFEPIEQNGSGRVKLAQAKLILDQEQRMAIAREIVRGAAHNMRANLA 119

Query: 119 MFELR--------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQY-GVTWNGR 163
            ++ R                +     +  ++L G EG   +  +A  A     + +  R
Sbjct: 120 YYQYRGNKALSKSTQEITKLMDRLHFAKDSDELMGFEGQITQTYFAAWALIDQRLDFLPR 179

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIAD 221
              P +    + IN  IS      Y VT            + F+HT      S   D+++
Sbjct: 180 VRRPPN----NPINCLISFINQLTYTVTRHEAFKTHLEETLSFLHTPSTGRSSLSLDLSE 235

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPA 281
             K         ++ R+N  + D            +      ++      L     +   
Sbjct: 236 PFKPVLSHGLIIKMVRKNMVD-DAWFDQKPGVCLLTETGRRNVVEQFSIRLEERYEERSF 294

Query: 282 PPEDAQPV 289
                +  
Sbjct: 295 REWLYREA 302


>UniRef50_A6UNF5 CRISPR-associated protein Cas1 n=1 Tax=Methanococcus vannielii SB
           RepID=A6UNF5_METVS
          Length = 322

 Score =  163 bits (412), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 42/291 (14%), Positives = 96/291 (32%), Gaps = 48/291 (16%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
            +I       V+  K G+     + ++  +++   + ++   + L+ +    +V + + G
Sbjct: 10  SKISKSGNRIVIESKDGVFES-SIENIEQVLICAPSSITTEFLELSVKNNVDVVLLNKYG 68

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSV-------- 134
             V      G  ++     Q KL  +    + ++++    +         ++        
Sbjct: 69  KPVGRFFGNGIEKTALKRKQLKL-TENWAGISIIKEFLSEKIENQIEHLNNISKENISEG 127

Query: 135 ----------------------------EQLRGIEGSRVRATYALLAKQYG--VTWNGRR 164
                                       +Q++G+EGS  +  + +L+K       +NGR 
Sbjct: 128 SLSKSISKINKSKNMLLEIKGENIAEIRDQIQGLEGSVSKIYFRVLSKSLPKKYQFNGRS 187

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADI 222
             P      D  N  ++     LY   E   + +G  P IG +HT      SFV+D  + 
Sbjct: 188 RKPAK----DYFNCMLNYGYGMLYSEIEKICIISGIDPTIGILHTDGQNRKSFVFDYIEK 243

Query: 223 IKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
            + + +    +E       + +   +   R      +    +I      L 
Sbjct: 244 YR-NIIDKIVYESFLNETIK-ENFFKEVERGYLLDEEGRKHIISKFNGYLN 292


>UniRef50_B0VIK5 Putative uncharacterized protein n=1 Tax=Candidatus Cloacamonas
           acidaminovorans RepID=B0VIK5_9BACT
          Length = 353

 Score =  162 bits (411), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 49/292 (16%), Positives = 97/292 (33%), Gaps = 47/292 (16%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
             +   D  F L  +   +T +    ++ I++     ++  A++LA      +V++ + G
Sbjct: 11  SYLRKKDEMFELSIED-RKTKLSPEKISSIVISNAATITTDAIQLAMDYNIDIVFLDKYG 69

Query: 83  VRVYASGQPGGARSDKLLY-------------------------QAKLALDEDLRLKVVR 117
                   P    +  +                           Q +       +    +
Sbjct: 70  SPYGRIWFPKIGSTVLIRRRQLEMLSDNVGLQFIKDWIAIKIMNQYRFVQRLISKRDCDK 129

Query: 118 KMFELRFGEPAPARRSV-------EQL----RGIEGSRVRATYALLAKQYG--VTWNGRR 164
            +F+ R      A   +       E+L     G EG   +  +++LA+       + GR 
Sbjct: 130 SIFQTRMQNMQEAAICIMQAEGKLEELSGSFMGWEGGASKNYFSILAELIPDAYKFEGRS 189

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADI 222
             P      D  N  ++     LY   E A++ AG  P +G +H+      SFV+D  + 
Sbjct: 190 SRPAK----DAFNAMLNYGYGILYSKVERALIIAGLDPYLGLLHSDNYNKKSFVFDFIEP 245

Query: 223 IKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
            +   V    F I  R+   P   +    + +  S+     L PL+ +    
Sbjct: 246 YR-ILVDEPVFYIFSRHKFSP-YFIEPVHQGVLLSTTGKKFLAPLLLEHFDE 295


>UniRef50_B6IX22 CRISPR-associated protein Cas1, putative n=2 Tax=Rhodospirillum
           RepID=B6IX22_RHOCS
          Length = 350

 Score =  162 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 52/319 (16%), Positives = 95/319 (29%), Gaps = 55/319 (17%)

Query: 15  VSMIFLQ--YGQIDVIDGAFVLIDK--------------TGIRTHIPVGSVACIMLEPGT 58
           ++ +++      +    G+  +  +                  T I    +  ++L   T
Sbjct: 1   MTTLYVTVPGAIVRTESGSLSVWIEVQADDGGPDDGPIRRKRLTSIEPHRLETLVLLGQT 60

Query: 59  RVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRK 118
            ++  A+RL       +  +   G        P    +D  L+Q  L    + RL   R 
Sbjct: 61  ALTPNAMRLCMAHRITVALLDGGGNLAARVVPPEARTADLRLHQYTLHHTPEERLIRARG 120

Query: 119 MFELRFGEPAP-----------------------------ARRSVEQLRGIEGSRVRATY 149
           +   +    A                                 + E L GIEG+  R  +
Sbjct: 121 VVAAKLHNAAEVLRAVRSNQSNPDIARAIAEVERTAATVADAVTPETLLGIEGNGARQYF 180

Query: 150 ALLAKQY--GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFV 207
           A L   +   + + GR   P      D  N  +S     L       + A G  P +GF 
Sbjct: 181 AGLRAAFVGDIRFTGRAQRPPP----DPANSMLSFGYVLLGNRIAGLLEARGIDPCLGFF 236

Query: 208 HTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACR--DIFRSSKTLAK 263
           H  +P   S   D+ + ++   V      +      +PD     A R   +  + +    
Sbjct: 237 HALRPGRPSLALDLLEELRQPVVDRLVLRLCNLRMLKPDMFEADAERPGGVRLTVEGRRT 296

Query: 264 LIPLIEDVLAAGEIQPPAP 282
            +   E  LA    +   P
Sbjct: 297 FLEEWEAQLARPLREQGTP 315


>UniRef50_C0QHV1 Putative CRISPR-associated protein (Uncharacterized protein,
           predicted to be involved in DNA repair) n=1
           Tax=Desulfobacterium autotrophicum HRM2
           RepID=C0QHV1_DESAH
          Length = 338

 Score =  160 bits (405), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 44/300 (14%), Positives = 92/300 (30%), Gaps = 48/300 (16%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            I      +   +  F L ++      +    V   ++     ++  A+ LA +    +V
Sbjct: 4   YIHSPGTYLTQKNEIFRLKNQD-RSLDLSPRKVESFVITNQAMITTQAINLALENNIDMV 62

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSV-- 134
           ++   G             +  +  +       D  L +V+ + + + G      +++  
Sbjct: 63  FLDAFGDPTGRIWFAKMGSTALIRRKQLEMDQNDSGLMIVKDLIKNKIGNQVKFLKTLKN 122

Query: 135 -----------------------------------EQLRGIEGSRVRATYALLAKQYG-- 157
                                                + G+EG+  RA + +LA+     
Sbjct: 123 ARPGKEHRFIDTILAIEKILQTLEVTDGENVIDLRNTIMGLEGTSARAYFKVLARAMPEK 182

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SF 215
             + GR   P      D  N  ++     LYG  E A + AG  P IGF+HT      S 
Sbjct: 183 YRFKGRSRRPAK----DPFNAVLNYCYGMLYGKVEKACIIAGLDPFIGFLHTDNYNKKSL 238

Query: 216 VYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
           V+D+ +  +       A  +        D    +    +  +      ++  ++  L   
Sbjct: 239 VFDLIEPFR-IFAETTAVYLF-TGRKMKDDYFDMYEHSVSLNKNGKPVVVEAMDKHLEEK 296


>UniRef50_A5UJ50 Uncharacterized protein predicted to be involved in DNA repair n=5
           Tax=Methanobrevibacter RepID=A5UJ50_METS3
          Length = 334

 Score =  159 bits (403), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 35/292 (11%), Positives = 86/292 (29%), Gaps = 52/292 (17%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV 83
            +   D   V+++K      I    V+ I +     ++  A+ L A+    L+ +   G 
Sbjct: 11  TLRKKDNQIVVMEKDNEIYRISANKVSDITIMAKGHITFDALNLMAKNNIKLISINYFGQ 70

Query: 84  RVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQ------- 136
             Y    P          Q + + +    L + ++    +        +++ +       
Sbjct: 71  INYILESPNQNNIVLKKLQYQASENH-KGLLISKEFITSKMKNQKSTIKTLNKNKKIKEV 129

Query: 137 -------------------------------LRGIEGSRVRATYALLAKQYG--VTWNGR 163
                                          + G EG      +  ++      + +  R
Sbjct: 130 KIIENKIKQNIKDFKNFKITLNDNIFTSKNKIMGFEGIASVNYWEAVSLLLPDEINFKKR 189

Query: 164 RYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIAD 221
              P++    D +N  ++   + L       I+  G  P  G +H    +  S ++D+ +
Sbjct: 190 NQKPEN----DVVNSMLNYGYAILASEIAKNIVTLGLDPYCGLLHADLKRRQSLIFDLIE 245

Query: 222 IIKFDTVVPKAFEIARRNPGEPDREVRL-----ACRDIFRSSKTLAKLIPLI 268
             +   V    F++   N        +             + + +AK+   +
Sbjct: 246 EFRQQIVDKTVFKLINTNQINETNIDKRNNSLKLESRKLLAGEIMAKIHSDL 297


>UniRef50_C5EH11 Crispr-protein cas1 n=1 Tax=Clostridiales bacterium 1_7_47FAA
           RepID=C5EH11_9FIRM
          Length = 342

 Score =  159 bits (403), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 40/309 (12%), Positives = 91/309 (29%), Gaps = 45/309 (14%)

Query: 11  LKDRVSMIFL--QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLA 68
           ++  ++ I++  +   + +     V   +   +  IP  +V  I+       S A +   
Sbjct: 3   MRKLLNTIYVTNELAYLWLDGENLVCKIENENKLRIPFDNVENIVCFNYIGCSPALMGKC 62

Query: 69  AQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDE--------------DLRLK 114
                 + +V   G  +              + Q     ++              + R  
Sbjct: 63  VGKSIPINFVSPQGKFLAKVCGETKGNVFLRVAQIDCFREQGLVLAQNTMAAKFCNTRQV 122

Query: 115 VVRKMF---ELRFGEPAPARRSV--------------EQLRGIEGSRVRATYALLAKQY- 156
           + R +     LR         S+              E + GIEG+  ++ +++  K   
Sbjct: 123 IKRTLHDNSNLRGDAEIQRTLSILEEGVDKLFQAENMESVIGIEGNCAQSYFSIFGKLIT 182

Query: 157 ----GVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKP 212
                 T+  R   P      D +N  +S   +       AA+   G    IGF H  + 
Sbjct: 183 NQKAPFTFELRTKHPP----LDPVNAILSFVYTLFTNEFAAALETVGLDSYIGFCHALRS 238

Query: 213 L--SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
              S   D+ +  +   V      +        +   +     ++ +     K++   ++
Sbjct: 239 GRSSLACDLVEEARC-IVERFVLTLLNLQIVGEEDFEKQISGAVWLNEDGRKKVLARWQE 297

Query: 271 VLAAGEIQP 279
                 + P
Sbjct: 298 KKRTDMMHP 306


>UniRef50_Q03KT5 CRISPR-associated protein, Cas1 family n=5 Tax=Streptococcus
           RepID=Q03KT5_STRTD
          Length = 334

 Score =  159 bits (403), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 39/294 (13%), Positives = 87/294 (29%), Gaps = 39/294 (13%)

Query: 15  VSMIFLQYG--QIDVIDGAFVLI-DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +S ++ Q     + + +   ++  D   I   + +  V  ++L    +++   ++  ++ 
Sbjct: 1   MSDLYSQRSNYYLSLSEQRIIIKNDNKEIVKEVSISLVDNVLLFGNAQLTTQLIKALSKN 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP---- 127
              + +    G  + +          K   QAK   +ED RL+V R +   +        
Sbjct: 61  KVNVYYFSNVGQFISSIETHRQDEFQKQELQAKAYFEEDFRLEVARSIATTKVRHQIALL 120

Query: 128 -----------------------APARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNG 162
                                       S+ ++ G EG   ++ +  L         +NG
Sbjct: 121 REFDTDGLLDTSDYSRFEDSVNDIQKAYSITEIMGYEGRLAKSYFYYLNLLVPDDFHFNG 180

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIA 220
           R          D  N  ++   S LY      I   G +   G +H       +   D+ 
Sbjct: 181 RSRR----TAEDCFNSALNFGYSILYSCLMGLIKKNGLSLGFGVIHKHHQHHATLASDLM 236

Query: 221 DIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
           +  +   V     E+ R              +D   + +        +   +  
Sbjct: 237 EEWRPIIVDNTLMELIRNGKLLL-SHFENKDQDFILTDEGREIFAWALRSRILE 289


>UniRef50_P71636 CRISPR-associated protein Cas1 n=11 Tax=Mycobacterium tuberculosis
           complex RepID=P71636_MYCTU
          Length = 338

 Score =  159 bits (402), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 44/325 (13%), Positives = 96/325 (29%), Gaps = 42/325 (12%)

Query: 18  IFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +++     +I   DG  ++  +    +  P+ ++  I L     ++   +    +    +
Sbjct: 4   LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDI 63

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP-------- 127
                 G        P  + + +L  Q     D    L + +++   +            
Sbjct: 64  QLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHT 123

Query: 128 ------------------APARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNGRRYDP 167
                                  S+ +L G EG+  +A +  L         + GR   P
Sbjct: 124 SGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRP 183

Query: 168 KDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKF 225
                 D  N  +S   S LY     AI        IGF+H       +   D+ ++ + 
Sbjct: 184 P----LDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRA 239

Query: 226 DTVVPKAFEIARRNPGEPDREVR-LACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPP- 283
             +      +      +     +      +F + +    +     + +A         P 
Sbjct: 240 PIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPH 299

Query: 284 ----EDAQPVAIPLPVSLGDAGHRS 304
               + A  + +   V + +AGH S
Sbjct: 300 RYTFQYALDLQLQSLVRVIEAGHPS 324


>UniRef50_O28401 Putative uncharacterized protein n=1 Tax=Archaeoglobus fulgidus
           RepID=O28401_ARCFU
          Length = 345

 Score =  158 bits (400), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 36/275 (13%), Positives = 82/275 (29%), Gaps = 48/275 (17%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV 83
            + + +G  V+ +K      +    +  +++     +S  A++L  +    +V++   G 
Sbjct: 11  YLGIENGLIVVKEKGKALRKVRPEDLKQVLIIGKAAISSDAIKLLLKNRVDVVFLDFNGE 70

Query: 84  RVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSV--------- 134
            +     P    +     Q     D+   + + ++  + +         ++         
Sbjct: 71  ILGRLSHPLIGTAKTRREQYLAYGDKRG-VHLAKEFIKAKMANQMAILTNLAKARKDSNP 129

Query: 135 --------------------------------EQLRGIEGSRVRATYALLAKQYGVT--W 160
                                           E+L GIEG   +  +  ++        +
Sbjct: 130 EVAESLLKAKKEIDACLNELDGVEAEMIDKVRERLLGIEGKASKHYWDAISLVIPEEYRF 189

Query: 161 NGRR--YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFV 216
           NGRR           D +N  ++   S L      A+  AG  P  GF+H       S  
Sbjct: 190 NGRRGIEIGSPRYAKDIVNAMLNYGYSILLAECVKAVELAGLDPYAGFLHVDVSGRSSLA 249

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLAC 251
            D+ +  +   V      +      +P+   +   
Sbjct: 250 IDLMENFRQQVVDRVVLRLISYRQIKPEDCEKRNM 284


>UniRef50_C3MWK6 CRISPR-associated protein Cas1 n=6 Tax=Sulfolobus
           RepID=C3MWK6_SULIM
          Length = 341

 Score =  157 bits (397), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 38/309 (12%), Positives = 88/309 (28%), Gaps = 55/309 (17%)

Query: 4   LPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHA 63
           +      +KD  + + ++ G I           K  ++  I    +  I++   + +S  
Sbjct: 42  MDKKIAFVKDYGAYLKIEKGLITCK-------IKDQVKWSIAPTELHSIIVLTNSSISSE 94

Query: 64  AVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVR------ 117
            V++A + G  +V+                      L Q      +  ++   +      
Sbjct: 95  VVKVANEYGIEIVFFNNNEPYAKLIPAKYAGSFKVWLKQLTAW--KRRKVDFAKAFIYGK 152

Query: 118 --------KMFEL------------RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG 157
                   + +E             R         + E++   E    +  +  +     
Sbjct: 153 VHNQWVTLRYYERKYGYDLKSQELDRLAREVMFVNTAEEVMQKEAEAAKVYWRGVKSLLP 212

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SF 215
            +   +    +  +  D  N+ ++     L  V   A+++ G  P IGF+H  +    S 
Sbjct: 213 KSLGFKGRRKRVSDNLDPFNRALNIGYGMLRKVVWGAVISVGLNPYIGFLHKFRSGRISL 272

Query: 216 VYDIADIIKFDTVVPKAFEIARRNPGEPDR------------------EVRLACRDIFRS 257
           V+D+ +  +   V  K     R +  +                     + R     I   
Sbjct: 273 VFDLMEEFRSPFVDRKLIGFVRESADKITDLKTVYSLFSDVKEDEIYTQARRLVNAILND 332

Query: 258 SKTLAKLIP 266
            +    L  
Sbjct: 333 EEYRPYLAK 341


>UniRef50_B8GDW2 CRISPR-associated protein Cas1 n=1 Tax=Methanosphaerula palustris
           E1-9c RepID=B8GDW2_METPE
          Length = 327

 Score =  157 bits (397), Expect = 5e-37,   Method: Composition-based stats.
 Identities = 41/276 (14%), Positives = 87/276 (31%), Gaps = 31/276 (11%)

Query: 31  AFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQ 90
             +++ K G  T  P+G V  +++  G  +  A ++     G  + +    G  V     
Sbjct: 26  RLLIVQKNGTTTEYPIGDVHHLLVVGGHTIHSAVLQHMQNAGNWVSFFAADGTPVGLIRP 85

Query: 91  PGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG------------------------- 125
           P     +++    + A      L + R     R                           
Sbjct: 86  PEDRVDEQVRAIQRHAPAHSYALGITRAALGRRLQVIGETTVVTGESPLYQGELEVLQDA 145

Query: 126 -EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
            +      +++++R +        Y ++A+        R          D +N  +S + 
Sbjct: 146 RQELEYLVTLDEIRRLHRLATDMYYEIMARTIPKGTGFR--RRTARPYMDPVNTMLSFSY 203

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPD 244
             L GV    +  A     IG +H G   + V D+ ++ K   V    F + R+     D
Sbjct: 204 GILSGVCAVHLAGAHLDANIGLLHQG-ERALVRDLTELFKPQMVDQPIFALVRQGITASD 262

Query: 245 REVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
            E  +       S   + +++  ++  +    I   
Sbjct: 263 YE--IGESRCTLSDALIRRMLLHLQTSIEVTAIGRQ 296


>UniRef50_C3MX12 CRISPR-associated protein Cas1 n=11 Tax=Sulfolobaceae
           RepID=C3MX12_SULIM
          Length = 304

 Score =  157 bits (396), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 43/295 (14%), Positives = 99/295 (33%), Gaps = 38/295 (12%)

Query: 6   LNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAV 65
           +  + + +  + I+++           ++I K   +  I    V  I++     +S +A+
Sbjct: 1   MRTLVISEYGAYIYVKK--------NMLVIKKGDNKVEISPSEVDEILITASCSISTSAL 52

Query: 66  RLAAQVGTLLVWVGEAGVRVYASGQPG-GARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
            LA   G  ++++                        Q +  + +   ++   ++   + 
Sbjct: 53  SLALTHGISVMFLNSRDTPWGILLPSVITETVKTKKAQYETIVAKKD-IRYGEEIISSKI 111

Query: 125 GEPAPA----------RRSVEQLRGI-EGSRVRATYALLAKQYG--VTWNGRRYDPKDWE 171
              +            R   ++L G  E +  R  +  +++     + ++GR     D +
Sbjct: 112 YNQSVHLKYWTRLTGTRNDYKELLGKDEPTAARIYWRNISQLLPKDIGFDGR-----DVD 166

Query: 172 KGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVV 229
             D  N  ++ + + LY      ++ AG  P +GF+H  +P   S VYD +++ K     
Sbjct: 167 GVDQFNMALNYSYAILYNTIFKYLVIAGLDPYLGFIHKDRPGNESLVYDFSEMFKPYI-D 225

Query: 230 PKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPE 284
                  R          RL  +D      +   L  LI   +     +      
Sbjct: 226 FLLVRALRSG-------FRLKVKDGLIEENSRGDLAKLIRKGMEEKVKEESDHNP 273


>UniRef50_B1YCK7 CRISPR-associated protein Cas1 n=2 Tax=Thermoproteaceae
           RepID=B1YCK7_THENV
          Length = 303

 Score =  155 bits (392), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 43/303 (14%), Positives = 86/303 (28%), Gaps = 45/303 (14%)

Query: 15  VSMIFLQYGQ-IDVIDGAFVLIDKTGIRTHIPVGSVACI-MLEPGTRVSHAAVRLAAQVG 72
           + ++  ++G  +     A V+  + G    IP+  V  + +L  G  +S   VR  A+  
Sbjct: 1   MEVVVKEHGVSLGYSRWALVVRRRGGAAERIPIHQVDRLWILTGGVSISSRLVRALARSF 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARS-DKLLYQAKLALDEDLRLKVVRK------------- 118
             +V+    G        P    +      Q +  L+    L++ +              
Sbjct: 61  VDVVFFDGRGNPAARLFPPEANGTVAHRRAQYEAYLNGRG-LELAKLVVYGKIVNQAAAL 119

Query: 119 ----MFELRFGEPA--------------PARRSVEQLRGIEGSRVRATYALLAKQYGVTW 160
               ++     +                P     + + G EG      +A L+K +G   
Sbjct: 120 RRAGLWRRELYQELAGAASRVAEAAAAVPRCGDPQCVLGHEGRAAAEYWAALSKAFGTP- 178

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYD 218
                  +D    D  N  ++     L        +  G  P  G++H  K    S V D
Sbjct: 179 ------TRDPNASDPFNLALNYGYGILRYAVWRQAVIHGLDPYAGYLHVDKSGRPSLVLD 232

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
           + +  +         +            ++   R          +L P I   +      
Sbjct: 233 LMEEFRPHI-DLMVLKAKPSADWLEGGVLKREARAALVEKWLEMRLEPTIARQVGLAVAH 291

Query: 279 PPA 281
              
Sbjct: 292 LEG 294


>UniRef50_C9LGP6 CRISPR-associated protein Cas1 n=3 Tax=Prevotella
           RepID=C9LGP6_9BACT
          Length = 295

 Score =  155 bits (392), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 41/298 (13%), Positives = 106/298 (35%), Gaps = 25/298 (8%)

Query: 14  RVSMIFLQYGQIDVIDGAFVLIDKT--GIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQ 70
           + S++F+    + + +G  V+I K        +P+  +  +M+      ++   +    +
Sbjct: 3   KRSLVFMHPATLSLRNGQMVIIRKEIPDDNLIVPIEDIGLVMINHAMVSLTIPLLNALTE 62

Query: 71  VGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPA 130
               +++  E G+    +      + +    +  L    +    + + +++         
Sbjct: 63  QNVAVIFCNEKGMP---ASMLYNLQGNTTQGE-TLHNQLEAGEVLKKTLWKQIIEAKIKN 118

Query: 131 RRSVEQLRGIEGSRVRATY------------ALLAKQYGVTWNGRRYDPKDWEKGDTINQ 178
           + ++    G EGS ++  Y             + A+ Y     GR +       G  IN 
Sbjct: 119 QAALLNKMGKEGSILKPLYTNVKSGDSDNREGIAARLYWTALFGRDFIRDRNIPG--INS 176

Query: 179 CISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIA 236
            ++   S L      A++++G  PA+G  H  +  +F    D+ +  +   V    FE+ 
Sbjct: 177 LLNYGYSVLRAAVTRALVSSGLFPALGIFHHHRSNAFPLSDDLMEPFRP-FVDEIVFELT 235

Query: 237 RRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ-PPAPPEDAQPVAIPL 293
            +   E +   +     +       +K+   +   L+           ++ + + +PL
Sbjct: 236 AQGEAELNTATKSRLIRVLYVDTYFSKITRPLSVGLSMTMASLAKCYAKEQKKLVVPL 293


>UniRef50_Q1CW50 CRISPR-associated fusion protein Cas4/Cas1 n=5 Tax=Bacteria
           RepID=Q1CW50_MYXXD
          Length = 568

 Score =  154 bits (390), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 47/308 (15%), Positives = 88/308 (28%), Gaps = 48/308 (15%)

Query: 7   NPIPLKDRVSMIFL--QYGQIDVIDGAFVLI--DKTGIRTHIPVGSVACIMLEPGTRVSH 62
              P  D   ++ +     ++       V+   +  G  +  P   V+ ++     +VS 
Sbjct: 222 RLFPEDDVRQVLHVATPGTRVGRAAEELVVTPPEGEGAPSRQPGRMVSALIAHGAVQVSA 281

Query: 63  AAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFEL 122
            A+    +    + W      R       G     + L Q +      + L + R++   
Sbjct: 282 QALAYCVENDIGVHWFTSG-GRYLGGLGGGAGNVHRRLRQFEALRQASVCLGLARRLVAA 340

Query: 123 RFGEPA-------------------------------PARRSVEQLRGIEGSRVRATYAL 151
           +                                        S+E L G+EG+     +  
Sbjct: 341 KLEGQLRFLLRASRGDSESRQVLASAVRDLRALLPKCEEAPSLEVLLGLEGAGAARYFGA 400

Query: 152 LAKQ------YGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIG 205
           L           + + GR   P      D  N  +      ++   EAAI A G   A G
Sbjct: 401 LPYLQGEDVDTRLRFEGRNRRPPR----DRFNAVLGFLFGLVHREVEAAIRAVGLDVAFG 456

Query: 206 FVHTGK--PLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAK 263
           F H  +        D+ ++ +             R   + D +  +    ++ S    AK
Sbjct: 457 FYHQPRGTAGPLGLDVMELFRVPLADMPLVASVNRRAWDADADFEVTSEHVWLSKAGRAK 516

Query: 264 LIPLIEDV 271
            I L E  
Sbjct: 517 AIELYERR 524


>UniRef50_C5SD37 CRISPR-associated protein Cas1 n=1 Tax=Allochromatium vinosum DSM
           180 RepID=C5SD37_CHRVI
          Length = 346

 Score =  153 bits (386), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 55/291 (18%), Positives = 90/291 (30%), Gaps = 43/291 (14%)

Query: 17  MIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTL 74
           ++ + +   Q+ +  GA  L+       HIP+G +  +++     V     R  A+ G  
Sbjct: 6   LLVIDHRDTQLTLDGGALRLVTPGTKPRHIPLGVLGLVVVHGRALVGCDVWRALAERGIP 65

Query: 75  LVWVGEAGVRVYAS-GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP---- 129
            V     G  V A  G   GA       Q + A   + RL + R +   +    A     
Sbjct: 66  AVMQPGRGRGVCAWMGPALGATGVLRAAQHRAAEQVERRLMLARDLIAAKLLAQARVIER 125

Query: 130 --------------------------ARRSVEQLRGIEGSRVRATYALLAKQYGVTW--N 161
                                        S  ++ G+EGS   A +  L      TW   
Sbjct: 126 LPVASDPPETRTAVRRQQDLALARLGQASSTTEVMGLEGSAAAAWFRWLTLWLSPTWGFQ 185

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDI 219
           GR   P      D +N  +S   + L G   + I   G  PA G +H       S V D+
Sbjct: 186 GRNRRPPR----DPVNALLSLGYTLLGGEMLSVIQQQGLDPARGLLHELVPGRESLVLDL 241

Query: 220 ADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
            + ++   V      +  R    P+            S +   +       
Sbjct: 242 IEPLRPS-VDLVLLGMLDR-LLTPEDFTTSPEDGCRLSKEARGRFYQAWAQ 290


>UniRef50_A3XI90 Putative uncharacterized protein n=1 Tax=Leeuwenhoekiella
           blandensis MED217 RepID=A3XI90_9FLAO
          Length = 332

 Score =  152 bits (385), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 52/304 (17%), Positives = 94/304 (30%), Gaps = 52/304 (17%)

Query: 24  QIDVIDGAFVLIDKTGIRT-----HIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWV 78
            + V D  F +  +   +      HI    V   ++  G  ++  A+ LA +    +V V
Sbjct: 11  YLHVKDDMFEIKVREDKKQPFNVNHIAAHKVTSFIVSKGAALTTDAIALALKHNIDIVLV 70

Query: 79  GEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP--------- 129
              G  +          + K+  Q  +A      +  +++    +    A          
Sbjct: 71  ENNGHPMGRFWHSKLGSTTKIRKQQLVASLNQTGVYWIKEWLSQKLENQADYLNDLKKHR 130

Query: 130 ------------------------ARRSVEQL----RGIEGSRVRATYALLAKQYG--VT 159
                                       + QL    RG EGS  R  +  LA       +
Sbjct: 131 KNLHVYLDEKSAAILGFRKKIKEADGADINQLAESFRGWEGSAGRHYFEALATCIPDAYS 190

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVY 217
           + GR + P      D  N  ++ A   LY   E A++ AG  P +GF+H       S VY
Sbjct: 191 FKGRSFRP----AQDEFNALLNYAYGILYSRVERALMLAGLDPFVGFMHRDDYNSKSLVY 246

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           D  +  +        F+              +    +  +    A  +P   + L + +I
Sbjct: 247 DFIEPYR-IYAERFVFKSFSSKKMN-KSYFEVFEGGVSLNPDGKAFFVPEYLEYLDSDKI 304

Query: 278 QPPA 281
           +   
Sbjct: 305 KYKG 308


>UniRef50_A8ABK8 CRISPR-associated protein Cas1 n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8ABK8_IGNH4
          Length = 305

 Score =  152 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 56/313 (17%), Positives = 100/313 (31%), Gaps = 51/313 (16%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
            +  + G++ V DG     +  G   ++       I+      V+ AA+R   ++G  LV
Sbjct: 4   FVISEPGKLFVKDGGLAFANSKGEVAYLANLYDVIILATSKVSVTGAALRAMGRLGVDLV 63

Query: 77  WVGEAGVRVYASGQP-GGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP-------- 127
            +   G        P     +   L Q ++ L +   LK  + M   +  E         
Sbjct: 64  VLEWNGRPSGRFSSPVPNKSALARLKQYEVVL-KGEGLKYAKPMIVRKIIEQGRTLRYFA 122

Query: 128 ---------------------APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYD 166
                                A +  S E LR +E    R  + LL++ +   + GR   
Sbjct: 123 KTKRMKWLREASYELEKLSADASSAGSPEALRAVEAQAARLYWGLLSEAFP-EFPGRE-- 179

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIK 224
               E  D  N  I+ +   LY     A+   G  P  G  H  K    + VYD ++  K
Sbjct: 180 ---HEGCDPYNSAINYSYGILYSYAFKALSVTGLDPYAGLFHAIKSGREALVYDFSEQFK 236

Query: 225 FDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPE 284
              V  +A  +A     +              +  +   L   I+ +L + +    A   
Sbjct: 237 P-LVDRRALPLAHELEVD----------GCSLTYSSRKALGEEIKKLLESCDKTLLAEAW 285

Query: 285 DAQPVAIPLPVSL 297
           +    ++      
Sbjct: 286 NLA-SSMREGREY 297


>UniRef50_C0W0W5 CRISPR-associated Cas1 family protein n=1 Tax=Actinomyces
           coleocanis DSM 15436 RepID=C0W0W5_9ACTO
          Length = 287

 Score =  151 bits (381), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 50/290 (17%), Positives = 95/290 (32%), Gaps = 42/290 (14%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           GQI    GA  +         +P+  VA +++      S  A+      G  ++     G
Sbjct: 3   GQISSARGAISIEPDGKEPVLVPISDVAVLLIGHRVVFSGGALHRCLSAGVAVMLCDWRG 62

Query: 83  VRVYAS--GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRG- 139
           V    +         + + + QA+L   E  R    +++ + +    A A   +  LRG 
Sbjct: 63  VPEGGAFGWSDHTRVAARRIAQAQL--SEPRRKNAWKQIIKEKLRGQASALDDLG-LRGG 119

Query: 140 -----------------IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISA 182
                            +E    +  +  L         G    P        +N  +  
Sbjct: 120 DFLRELRKQVRSGDPANVEAQAAKFYWKALGG------EGFNRVPGARFG---VNGMLDY 170

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNP 240
           A + + G    A+L+AG  P++G  H G+  +F    D+ ++ +   V  + F +     
Sbjct: 171 AYAIVRGHGIRAVLSAGLEPSLGVFHHGRSNAFCLVDDLLEVFRPA-VDAQVFGLLGDGE 229

Query: 241 GEPD----REVRLACRDIFRSSKTLAKLIPLIEDVLA---AGEIQPPAPP 283
            E D      V +AC        T+  +              +++   PP
Sbjct: 230 VEFDEVKHDLVDIACGKFSVDGLTIPAVFEDFAQQFGLYIEDDVEKLVPP 279


>UniRef50_Q2FPW6 CRISPR-associated protein Cas1 n=1 Tax=Methanospirillum hungatei
           JF-1 RepID=Q2FPW6_METHJ
          Length = 303

 Score =  149 bits (377), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 42/282 (14%), Positives = 84/282 (29%), Gaps = 31/282 (10%)

Query: 26  DVIDGAFVLI-DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
            +      +     G  T IP+  ++  +L  G  +  + +    + G  + +    G  
Sbjct: 7   HIKSNRTEITIQHKGKITDIPIKDLSHFLLIGGHTIQTSTITSLVKEGVFISFCESDGEP 66

Query: 85  V-YASGQPGGARSDKLLYQ--------AKLALDEDLRLKV-VRKMFELRFG--------- 125
           V Y S        +    Q        A    +E ++ ++   + +    G         
Sbjct: 67  VGYISPYDYSLFKEIQNLQKTAAPYSYALACANESIKSRILAIEKYAEEIGPEILFSGEL 126

Query: 126 -------EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQ 178
                  +       +E+LR IE       Y +L +    T+  +          D +N 
Sbjct: 127 DILTGYAKELENMVLIEELRRIEQLVRDMYYEILGRLISPTYLFK--RRTSRPYLDPVNA 184

Query: 179 CISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARR 238
             S     L      A++     P  G+++ G   + V D+ +  K   +   A    R 
Sbjct: 185 IFSFGYGMLSSACTRAVIGGHLDPGHGYLNRGNQ-ALVQDLMNCWKPKMIDNHAIGFLRS 243

Query: 239 NPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
                +   R   R      + + +LI L    +    I   
Sbjct: 244 GRLHQNGYERTKDR-CILHDEVIEELIHLFSKSIQEELINTQ 284


>UniRef50_A6UVX9 CRISPR-associated protein Cas1 n=2 Tax=Methanococcales
           RepID=A6UVX9_META3
          Length = 334

 Score =  149 bits (377), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 44/295 (14%), Positives = 90/295 (30%), Gaps = 53/295 (17%)

Query: 25  IDVIDGAFVLI-DKTGI--RTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWV--- 78
           I   +  F +  +K G   +T IP   +  I+L     ++  A+ LA +    ++++   
Sbjct: 12  ISKKEDRFRVELEKDGKIIKTDIPATKIERIILSNNGTITTGAISLAIENNIPIIFLKWE 71

Query: 79  ----------------GEAGVRVYASGQPGGARSDKLLYQ---------------AKLAL 107
                                  ++    G   +   + Q                    
Sbjct: 72  EPTGMIWHCRIGKTAKTRRSQLKFSESINGIRFASNWIKQKMGNQLNYLKDLKKNHNHKG 131

Query: 108 DEDLRLKVVRKM------FELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG--VT 159
           D D  +K +         +     +  P R   + + GIEG   +  +  +         
Sbjct: 132 DFDTVIKNINNYIMELTQYTNNIDDKLPHREIKDTIIGIEGIASKYYFEGINHALPKNYK 191

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVY 217
           +  R   P      D  N  ++     LY + E  ++ AG  P +GF+H       + VY
Sbjct: 192 FKERSRRPAR----DKFNALLNYGYGMLYPMVEKCLIVAGLDPYVGFIHADNYNKTTLVY 247

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
           D+ ++ +                 +      +    I  S     +  P I+D++
Sbjct: 248 DVIEMYRAHI-DRGVVNFINSKKVK-GSHFNILENGISLSDDGKGEFAPYIKDIV 300


>UniRef50_C8PKY6 Putative CRISPR-associated protein Cas1 n=1 Tax=Campylobacter
           gracilis RM3268 RepID=C8PKY6_9PROT
          Length = 731

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 39/246 (15%), Positives = 83/246 (33%), Gaps = 32/246 (13%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           + +  G  VL  K  I+   P+  ++ I++     +S A ++  A+    + ++ E    
Sbjct: 421 LALSQGKLVLKSKGAIKHKFPINQISQIIINAQISLSSAVIKECAKKKISINFIDEKTNL 480

Query: 85  VYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA---------------- 128
            YA+     +   K        L     L++ ++    +                     
Sbjct: 481 SYATLISANSAIPKTAASQISLLTTKKSLRIAQQFIIGKLKNQINYLKYLGKYHKNLGAE 540

Query: 129 ------------PARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
                       P   SV +L G EGS   + +  +AK     +             D +
Sbjct: 541 IKAMQEILKLRVPGAASVSELMGFEGSAANSYWQAIAKAVDYEFGFSA--RVTQGATDIV 598

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPKAFE 234
           N  ++   + LY     +I AAG +P + ++H    +  +  +D+ +  +   V      
Sbjct: 599 NSALNYGYAILYSKILKSIAAAGLSPHVSYLHALDEQKPTLAFDLIEEFRAFIVDRAVIS 658

Query: 235 IARRNP 240
           +  +N 
Sbjct: 659 MVNKNE 664


>UniRef50_D2QT50 CRISPR-associated protein Cas1 n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QT50_9SPHI
          Length = 351

 Score =  148 bits (374), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 60/313 (19%), Positives = 102/313 (32%), Gaps = 60/313 (19%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPV----GSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVG 79
            + V D  F +  K      I        V  I+L  GT +S  AVRLA +    +V++ 
Sbjct: 11  YLHVKDAMFDVRRKGEDGKVISATYSAEKVTHILLATGTSLSTDAVRLAMRHNVDIVFIE 70

Query: 80  EAGVRVYASGQPGGARSDKLL-------------YQAKLA--LDEDLRLKVVRKMFELR- 123
           + G  +          + K+                 +       D ++  +R + + R 
Sbjct: 71  QQGDPIGRVWHAKLGSTTKIRKRQLEASLGPDGLRWVRAWLLAKLDNQMGFIRSLKKHRP 130

Query: 124 -------------------------FGEPAPARRSV----EQLRGIEGSRVRATYALLAK 154
                                     GE  PA   V    + LRG+EG+  R  +  L+ 
Sbjct: 131 QHAGYLDDKLVRIEAMALSISTLASVGEQTPATTCVADVADTLRGLEGTAGRLYFETLSY 190

Query: 155 QYG--VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG-- 210
                  ++GR   P      D  N  ++     LYG  E  ++ AG  P +GF+H    
Sbjct: 191 VLPKEYQFSGRSSRP----AQDAFNAFLNYGYGMLYGKVEKTLMMAGLDPYVGFLHRDDY 246

Query: 211 KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDR--EVRLACRDIFRSSKTLAKLIPLI 268
             LS VYD  +  +        F +            EV  +   +  ++   A L+   
Sbjct: 247 NQLSMVYDFIEPYRGW-TDEVVFRLFTAKKVNKAHIGEVSGSRTGVSLNADGKALLVNAF 305

Query: 269 EDVLAAGEIQPPA 281
            + +    I+   
Sbjct: 306 NECMDNDPIRYRG 318


>UniRef50_A1WUP2 CRISPR-associated protein Cas1 n=1 Tax=Halorhodospira halophila SL1
           RepID=A1WUP2_HALHL
          Length = 320

 Score =  148 bits (373), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 50/295 (16%), Positives = 98/295 (33%), Gaps = 45/295 (15%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +  +++     ++++   A  + +       +P+  +  +++     +S   +   A+ G
Sbjct: 1   MGTLYIDRRRTRLELAHKALTIREPEAQPRSVPLSLIDRLIVIGQVELSSGVLTTLAESG 60

Query: 73  TLLVWVGEAGVRVYASGQP-GGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG------ 125
             LV++   G R  A  +  G   + + L Q +L   E  R    R++  LR        
Sbjct: 61  VSLVFMPSRGQRRSAFLRSEGHGDAVRRLGQYRLIHLEAERQAWARRLVRLRLAGQQRLL 120

Query: 126 ------------------EPAPARRSV--------EQLRGIEGSRVRATYALLAKQYG-- 157
                                 A ++         EQLRG EG+   A +      +   
Sbjct: 121 ASALYRRPDQRQPLTAAHREIEAAQATVRREAPAGEQLRGQEGTAAAAFFRGYGALFAEA 180

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSF 215
           + ++GR   P      D +N  +S   +  +G    A+ AAG  PAIG +H       S 
Sbjct: 181 LGFSGRNRRPPR----DPVNAVLSLGYTLAHGDALRAVTAAGLDPAIGVLHEPAWGRDSL 236

Query: 216 VYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
             D+ +I +   V    +E+      +           +              E 
Sbjct: 237 ACDLTEIARAR-VERLTWELFASETLQRTDFTNSTE-GVRLGKAARQTFFGCWER 289


>UniRef50_D0YU98 Crispr-associated protein Cas1 n=1 Tax=Mobiluncus mulieris 28-1
           RepID=D0YU98_9ACTO
          Length = 309

 Score =  147 bits (370), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 45/296 (15%), Positives = 97/296 (32%), Gaps = 41/296 (13%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
            G +   +GA V+  + G    +P+  VA ++    TR S  +V    +  T +++    
Sbjct: 18  RGFVTSTEGALVVRPEEGEERRVPISDVAVVLFGVDTRFSAGSVHRILKNDTAVIFCDWK 77

Query: 82  GVRVYAS--GQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA-------PARR 132
           GV    +           + + QA  ++     +   R +     G+         P  +
Sbjct: 78  GVPYGHAYPWGDHTRVGARQIAQANASIPARKSVW-ARLIKSKVLGQAEVLEFFGRPNGK 136

Query: 133 SVEQLR---------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDT--INQCIS 181
            +++L           IEG   R  +  L       W+ + +       GD   IN  + 
Sbjct: 137 RLKELVKDIRSGDPSNIEGQAARIYWESL-------WDDQDFRRTPGAGGDIFTINAMLD 189

Query: 182 AATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIARRN 239
              + L G    A+ A+G   ++G  H G+        D  +  +        + +    
Sbjct: 190 YGYTILRGHAMRAVAASGLISSLGVAHRGRSNPWNLADDFIEPFRPAI-DYSVYLLVSEC 248

Query: 240 PGEPDREVRLAC----RDIFRSSKT-----LAKLIPLIEDVLAAGEIQPPAPPEDA 286
             + + E++        D+F +++      +  L      ++     +   P    
Sbjct: 249 -IDDEAEIKKRLVNSAGDVFTATRKSIPAEMTLLAQHYGQLIEGDIGKFGVPSWKP 303


>UniRef50_A3CTI4 CRISPR-associated protein Cas1 n=1 Tax=Methanoculleus marisnigri
           JR1 RepID=A3CTI4_METMJ
          Length = 392

 Score =  146 bits (369), Expect = 8e-34,   Method: Composition-based stats.
 Identities = 43/274 (15%), Positives = 87/274 (31%), Gaps = 31/274 (11%)

Query: 33  VLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR---VYASG 89
           ++I +       P+ +V  +++  G  +  +AV    + G  +      G     +Y  G
Sbjct: 105 LIIARGSDTRRYPIQAVKHLLIVGGHTLHTSAVTNLLKAGAAITIFDIDGTPVGYLYPYG 164

Query: 90  QPGGARSDKLL--------YQAKLALDEDLRLKVVRKMFEL---------------RFGE 126
                               Q         RL ++ ++++                +  E
Sbjct: 165 YRPDESVRLAQERAGPHRFAQPLARASLQSRLLLLEELYDHAGHDIFYAGELDFLHQARE 224

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
              A  ++E LR +        Y +L++        R          D +N   +   + 
Sbjct: 225 ELSASVTMENLRRLSRLTTDMYYEILSRTLPPELGFR--RRTSRPYLDPVNAMFALGYAM 282

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDRE 246
           +YG    +++ A   P +G +H G   SFV+D+ +  K   V       AR      D E
Sbjct: 283 IYGNCCVSVVGAHLDPDLGMLHEG-AGSFVHDLIEPQKASMVDRAVIRFAREEISSGDYE 341

Query: 247 VRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPP 280
                +  +      ++L   + D +    I   
Sbjct: 342 C--GEKRCYLGGDLSSRLAAALRDSIDQARIDAQ 373


>UniRef50_C8N6V7 Putative uncharacterized protein n=1 Tax=Cardiobacterium hominis
           ATCC 15826 RepID=C8N6V7_9GAMM
          Length = 334

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 40/297 (13%), Positives = 89/297 (29%), Gaps = 44/297 (14%)

Query: 15  VSMIFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           +S +++     ++ V     +  +     + +P+  +  I ++    +S A +    +  
Sbjct: 1   MSTLYIDRQNTRMTVSGNTLIFYENGERASTLPLHIIDRICIKGDLALSAADLGKLGEHN 60

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA---- 128
             ++ +     +           + + L QA  + D     +  +     +         
Sbjct: 61  IGVLILSGREQQPTIYLPCARKDALRRLAQAHFSQDNTFCTRQAQSWITEKIQREQDLLR 120

Query: 129 ----------------------------PARRSVEQLRGIEGSRVRATYALLAKQYG--V 158
                                            +  LRGIEGS   +T+A +A      +
Sbjct: 121 ELQTRPHRGGHQLHENLEQLEKSRLRLQNPINDLATLRGIEGSAASSTFAAIACVLPESL 180

Query: 159 TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFV 216
            +  R  +P      D  N  +S   + L+      I   G  P IG+ H+ +    S  
Sbjct: 181 HFTKRNRNPPR----DPYNVGLSLGYTLLHYAMVRQIHLTGLDPCIGYYHSIEHGRESLA 236

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
            D+ + ++         E        P+ +  +            A+  P  E+ L 
Sbjct: 237 CDLIEAMRPLVTAWTI-EAFHDRILRPE-DFTMQNEACQMGKAARARYYPAFENALK 291


>UniRef50_B3PMY9 Putative uncharacterized protein n=1 Tax=Mycoplasma arthritidis
           158L3-1 RepID=B3PMY9_MYCA5
          Length = 297

 Score =  145 bits (367), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 49/280 (17%), Positives = 94/280 (33%), Gaps = 28/280 (10%)

Query: 33  VLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTLLVWVGEAGVRVY-ASGQ 90
           ++++K G +  IP   +  ++ E     ++   +      G  ++  G   +        
Sbjct: 21  LVVNKDGTKITIPTSQIDTVLFENDKLTITLPLINDLVDHGINIIVCGRNHMPKAQIIPF 80

Query: 91  PGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRG-----IEGSR- 144
            G   +  L  Q K   D   R  V R++ +L+  +       +  LR      +E    
Sbjct: 81  QGYYNAKILQKQIKWDNDFKER--VWRRIIKLKIRQTMVMLEHLAILRDDDKVKLEDYAN 138

Query: 145 ------VRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAA 198
                 +       AK       G ++  K     DT N  ++   S L      AI + 
Sbjct: 139 SVKAFDITNCEGHCAKLNFKILFGEKFVRKTNTMEDTYNAYLNYGYSVLLSYVARAICSK 198

Query: 199 GYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAFEIARRNPGEPD-REVRLACRDIF 255
           GY   +G  H           D+ +  +   V    ++  R + GEP+ +E +     IF
Sbjct: 199 GYDNRLGIFHRSYSNFYPLACDLMEPFRC-IVESLVYKHVRISRGEPNFQEFKEELFTIF 257

Query: 256 RSS--------KTLAKLIPLIEDVLAAGEIQPPAPPEDAQ 287
                        +  +  L+  VL+  +I+ P     A+
Sbjct: 258 YKHFNCQGENLMLIDCIDKLVVLVLSDHDIKGPYFNWSAE 297


>UniRef50_B4ATI8 Crispr-associated protein Cas1 n=5 Tax=Proteobacteria
           RepID=B4ATI8_FRANO
          Length = 318

 Score =  145 bits (366), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 46/274 (16%), Positives = 92/274 (33%), Gaps = 37/274 (13%)

Query: 17  MIFLQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTL 74
           +I  +YG  + +  G  V+ +K   +   P+  +A + +   G   S   V   +  G  
Sbjct: 4   LIISEYGIYLGLESGRLVVKNKDDKKY-FPLNRLATLSIAKKGVSFSSDLVEQFSLRGIK 62

Query: 75  LVWVGEAGVRV-YASGQPGGARSDKLLYQAKLALDEDLRLKV---VRKMFE--------- 121
           L ++   GV      G    A     + Q +      L L +     K+           
Sbjct: 63  LFFLDFRGVAHSMLVGANQHAVVQARINQYRYIDRNALTLSIKLIAAKIKNQRATLNYFN 122

Query: 122 ---------------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYD 166
                           R  +     +++  + G EG      ++ LAK   ++ +    +
Sbjct: 123 KHHKSINLLNAIEELKRVAQLIKNAKTLNDVLGYEGYAANIYFSSLAKDKFLSASF--AN 180

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIK 224
            +     +  N  ++   + L      AI  AG  P +GF+H  +P   S V D+ +  +
Sbjct: 181 REGRGSQEIANSMLNFGYAILSSYILNAITNAGLEPYLGFLHQKRPGKMSLVLDLMEEYR 240

Query: 225 FDTVVPKAFEIARRNPGEPDREVRLACRDIFRSS 258
              V     ++  R   +  + +    + I  S 
Sbjct: 241 AWVVDRVVIKL--REQYKNKQYIDTKLKSILISE 272


>UniRef50_UPI0001BCCAFD hypothetical protein SnoxA4_00467 n=1 Tax=Selenomonas noxia ATCC
           43541 RepID=UPI0001BCCAFD
          Length = 281

 Score =  145 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 33/251 (13%), Positives = 65/251 (25%), Gaps = 37/251 (14%)

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELR- 123
           +    ++G  + W+   G               +   Q  L  D    L + RK+   + 
Sbjct: 1   MVELLRLGIPVTWLSRTGYFFGRLESTRHVNVFRQERQI-LLRDSFFYLAMARKVIAAKA 59

Query: 124 ----------------------------FGEPAPARRSVEQLRGIEGSRVRATYALLAKQ 155
                                         +  P   +  QL G EG+  +  +  L   
Sbjct: 60  HNQFILLRRYNRSASLPEVRTAMAEITALSKHIPRCETNTQLMGYEGAIAKVYFRALGLL 119

Query: 156 YGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPL 213
               +             D  N  +S   + L       +   G  P  GF+H    +  
Sbjct: 120 VPEAFAF--VKRSRRPPMDPFNTMLSFGYTLLMYDLYTVVNNEGLHPYFGFLHALKNRHP 177

Query: 214 SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLAC---RDIFRSSKTLAKLIPLIED 270
           +   D+ +  +   V      +   +   P+            IF + +  A  +   E 
Sbjct: 178 ALASDLMEEWRPVLVDAMVLSLVHHHEMRPEHFAPSEEEGRPGIFLTREGRAIFLRAYEK 237

Query: 271 VLAAGEIQPPA 281
            + A  +    
Sbjct: 238 KMRATSLYGGG 248


>UniRef50_B8D4S7 CRISPR-associated protein Cas1 n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D4S7_DESK1
          Length = 328

 Score =  142 bits (358), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 37/291 (12%), Positives = 89/291 (30%), Gaps = 49/291 (16%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           ++    G  ++  K      +P+  +  +++   G   S   +R   + G   + +   G
Sbjct: 12  RLRYRKGLMLIESKNEKN-EVPLTDLEQVVIETGGVWFSSKLIRKMVEYGIDFIVLDHRG 70

Query: 83  VRVYASGQPG-GARSDKLLYQAKLALDED--------------LRLKVVRKMFELRFGEP 127
                   P      +    Q                       +  ++++ +     E 
Sbjct: 71  YPAGRLYPPFISRTVETRRAQYAAYESWRGVHVMRELVYSKLANQAGLLKRYYMYTIMEE 130

Query: 128 APAR-------------------RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPK 168
                                   + E+LR +E    R  +  L+           ++ +
Sbjct: 131 LKDAYKKIIELAYRARMLEAEFEEAREKLRQLEAEAARIYWPSLSILIPKELG---FNSR 187

Query: 169 DWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFD 226
           D +  D +N  ++ A   LYG +   ++ AG  P  GF+HT +       +D+ ++ +  
Sbjct: 188 DQDSEDLVNTSLNYAYGILYGESWKVLVLAGLDPYAGFMHTDRSGKPVLAFDLIEMFR-F 246

Query: 227 TVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
           T       + R          +    +     ++ A+++  I   L   + 
Sbjct: 247 TADSTLLAMYRHG-------WKPRVLNGLLDYESRARIVESIMKTLENTKT 290


>UniRef50_A6DE79 CRISPR-associated protein Cas1/Cas4 n=1 Tax=Caminibacter
           mediatlanticus TB-2 RepID=A6DE79_9PROT
          Length = 281

 Score =  142 bits (358), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 34/288 (11%), Positives = 92/288 (31%), Gaps = 35/288 (12%)

Query: 15  VSMIFLQY-GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGT 73
           ++ + +    +++V +   ++ DK      +P+  +  + L     ++   +    +   
Sbjct: 1   MNRVIIDRECKLEVRNSQLIVEDKK-----VPLRYIDFLYLIGEIEINTKTIMKLLKEDI 55

Query: 74  LLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRS 133
            ++        +Y         +D    Q          + + R++   +  +       
Sbjct: 56  SILIQNRGFGLIY---PQKSKNNDLKKKQ---YFALKKEVDIAREIIRKKIQKSIDNLVK 109

Query: 134 V-----------------EQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
           +                 + L GIEG+  +  +      +  T    +         D +
Sbjct: 110 LNKKIVVDFKILDEISSKDSLLGIEGNFAKEYFKEYFSLFDKTLT--KGYRSKRPPEDVV 167

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFE 234
           N  +S   + LY      ++  G+   I ++H      +S   D+ ++ + D V    +E
Sbjct: 168 NALMSYLYTLLYYEIANRLIFYGFEVGISYLHESFRDHMSLASDLLEVFRSD-VDVFVYE 226

Query: 235 IARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAP 282
           +         ++     + IF  S+   ++   I+D     +I     
Sbjct: 227 MFDNKKV-IKKDFTKEKKGIFLRSEKRKEIWSDIKDFFENLKIDEEIA 273


>UniRef50_A3DLB7 CRISPR-associated protein, Cas1 family n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DLB7_STAMF
          Length = 341

 Score =  142 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 39/286 (13%), Positives = 75/286 (26%), Gaps = 48/286 (16%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           +    G  V++ + G     PV  V  +++     +S   ++L A  G  ++     G  
Sbjct: 19  LRKKHGRIVVVSRGGRE-EFPVRRVREVIISGKAGISTELLKLLADSGIDVLVTSYTGRP 77

Query: 85  VYASGQPGG-ARSDKLLYQAKLALDEDLRLKVV--------------------------- 116
           V               + Q +   D                                   
Sbjct: 78  VALFVHARSGGSVRNRIEQYRSLEDGRACKAAAMIISGKLSNQVSNLKYYSKPRKNISQE 137

Query: 117 -RKMFE-----LRFGEPAPARRS------VEQLRGIEGSRVRATYALLAKQYGVTWNGRR 164
            + ++E      +  E      +       E +  IE       +  +    G      R
Sbjct: 138 SKILYEKAEEIKKLREKLRDIETSDLGKCRENIMSIEAQAANTYWDGMRIVLGKYGFKER 197

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADI 222
                 ++ D +N C++   + L G     +L     P  GF+H  +P   S VYD+ + 
Sbjct: 198 VKRGRGKEVDPVNLCLNIIYNKLAGTVWKYVLRFSLDPFQGFLHARRPGKLSLVYDLMEP 257

Query: 223 IKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
            +             R     D+           +     K     
Sbjct: 258 FRP-IADR----FIARFLYRLDQGFLRRASGAELAKLLTKKYYEEF 298


>UniRef50_Q8F874 Putative uncharacterized protein n=1 Tax=Leptospira interrogans
           RepID=Q8F874_LEPIN
          Length = 254

 Score =  141 bits (355), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 30/187 (16%), Positives = 63/187 (33%), Gaps = 5/187 (2%)

Query: 97  DKLLYQAKLALDEDLRLKVVRKMFEL-RFGEPAPARRSVEQLRGIEGSRVRATYALLAKQ 155
             L   A+ + +E  +  +   + ++ +         S+E +RG EG+  +  +++    
Sbjct: 33  SVLSRTARKSKNESEKQDIKEAIGKIEKNISLLEKAESIESIRGYEGASAKTYFSVFDYC 92

Query: 156 YGVTWNGRRY-DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL- 213
                   ++            N  +S   S L     A   A G  P IGF+H  +P  
Sbjct: 93  IIQQKEDFQFHKRTRRPPRSRTNALLSFLYSLLTNDCIAVCQAVGLDPYIGFLHDERPGR 152

Query: 214 -SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVL 272
            S   D+ +  +   +    F +  R   +    +       F +  +  +LI   ++  
Sbjct: 153 PSLALDMMEEFRP-FIDRLVFTLINRKQIQVSDFLEKPGSVFFINDDSRKELIKSYQERK 211

Query: 273 AAGEIQP 279
                 P
Sbjct: 212 KEEIFHP 218


>UniRef50_A7I668 CRISPR-associated protein Cas1 n=1 Tax=Candidatus Methanoregula
           boonei 6A8 RepID=A7I668_METB6
          Length = 310

 Score =  140 bits (354), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 32/276 (11%), Positives = 81/276 (29%), Gaps = 32/276 (11%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
             I        ++   G     P+  +  +++  G  ++        + G+ + +    G
Sbjct: 15  AHIKSTQKKLSIL-AKGKVEEYPLEEIQNLLIVGGHHLNSTTFSHLLRNGSYISFFEPDG 73

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF------------------ 124
             +      G      +    + A  +     + +   + R                   
Sbjct: 74  SPLGILKPWGSTCDTTIRALQEGAPRDRYATALAQAALKSRLIAIEHIQDQQGSSLFYEG 133

Query: 125 --------GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
                            ++++R +        Y +L++     ++ R        + D I
Sbjct: 134 ELQILHNALHNLEYMVKLDEIRRLSDLTANMYYEILSRDIPREFDFR--RRTVRPQCDPI 191

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIA 236
           N  +S   + L+G     ++ A   P +G ++ G   + V D+    K   +    + IA
Sbjct: 192 NAMLSFGYAMLFGNCCVPVIGARLDPDLGILYEG-SGALVQDLMASFKAQMIDGVIWSIA 250

Query: 237 RR--NPGEPDREVRLACRDIFRSSKTLAKLIPLIED 270
           R   N G+ +                ++     I++
Sbjct: 251 RDSLNVGDFEITSNRCILSDNLIQNLMSSFRKSIDN 286


>UniRef50_A3MVN2 CRISPR-associated protein, Cas1 family n=4 Tax=Thermoproteaceae
           RepID=A3MVN2_PYRCJ
          Length = 294

 Score =  140 bits (354), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 55/270 (20%), Positives = 92/270 (34%), Gaps = 39/270 (14%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACI-MLEPGTRVSHAAVRLAAQVGTLLVWVG 79
            YG         +++++ G R   P+  V  + +L  G  ++  A+R   + G ++    
Sbjct: 7   SYGTRIRTRKGLLVVERGGERREYPLHQVDEVFILTGGVSITSRALRALLRAGAVVAVFD 66

Query: 80  EAGVRVYASGQP-GGARSDKLLYQAKLALD----EDLRLKVVRKM---------FELRFG 125
           + G  +    +P G A  +K   Q   A      +  R  V +KM         +  R  
Sbjct: 67  QRGEPLGIFMRPVGDATGEKRRCQYAAAAGGRGLQWAREWVWKKMRGQLQNVKAWRRRLA 126

Query: 126 E-------------PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEK 172
                            A  S  ++   E +   A +    +  G  + GR     D E 
Sbjct: 127 HYGDYVEQIGRALEALRAAASPGEVMEAEAAAAEAYWRAYGEVTG--FPGR-----DQEG 179

Query: 173 GDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDT--V 228
           GD +N  ++     L  +   +IL AG  P +GF+H  K    S V D  +  +     V
Sbjct: 180 GDPVNAALNYGYGVLKALCFKSILLAGLDPYVGFLHVDKSGRPSLVLDFMEQWRPRVDAV 239

Query: 229 VPKAFEIARRNPGEPDREVRLACRDIFRSS 258
           V K         G  D + RL         
Sbjct: 240 VAKVAGELATENGLLDHKSRLRVAAAVLEE 269


>UniRef50_D2QAN8 CRISPR-associated protein Cas1 n=2 Tax=Bifidobacterium dentium
           RepID=D2QAN8_9BIFI
          Length = 305

 Score =  140 bits (353), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 52/296 (17%), Positives = 91/296 (30%), Gaps = 37/296 (12%)

Query: 23  GQIDVIDGAFVLIDKTG-IRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
           G I    G   +          +P+   A +++      S A +   A+ G  ++     
Sbjct: 15  GTISYERGRMKVRKHGESESVCVPLAQAAVVLIGLRVCCSSAVLHEMAKAGVSVMLCDWR 74

Query: 82  GVRVYASGQPGGARSDKLLYQ-AKLALDEDLRLKVVRKMFELRFGEPAPARRSVE----- 135
           G+   A        S+  + Q A+  +    +     K+ + +    A    S+      
Sbjct: 75  GIPDAALHSWTNVPSEVAVRQIAQSEMTLPRKKNAWAKIVKAKIRGQASCLDSLGIEGGG 134

Query: 136 QLRGI------------EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
            LRGI            EG   R  +  +        +G+R+     +     N  +  A
Sbjct: 135 ALRGIASSVRSGDTSNYEGYAAREYWKRI-----FIGDGKRFKRIPGDGT-GRNAQLDYA 188

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPG 241
            + L G    AIL+AG  P +G  H G+   F    D+ ++ +       A        G
Sbjct: 189 YTILRGFAVKAILSAGLIPTLGVNHHGRSNYFCLADDLLEVYRPAIDYWVA--QLEPEDG 246

Query: 242 EPDREVRLACRDIFRSS-----KTLAKLIPLIEDVLA---AGEIQPPAPPEDAQPV 289
             D+ V+    D           T+   I             +I     PE   P 
Sbjct: 247 PSDKNVKRYLADSVNQQFDSSGLTIPSSISDFAQQFGLYCEKKIDALEVPEYRGPY 302


>UniRef50_C6I8L1 CRISPR-associated protein n=1 Tax=Bacteroides sp. 3_2_5
           RepID=C6I8L1_9BACE
          Length = 756

 Score =  140 bits (353), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 45/282 (15%), Positives = 89/282 (31%), Gaps = 56/282 (19%)

Query: 38  TGIRTHIPVGSVACI-MLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARS 96
            G   + P  ++  I ++  G  +S  A+         + +    G +      P     
Sbjct: 446 QGKIINKPSPALKHITVVGKGISLSSNAITYCMNHKIPIDFFDGRGKQYSTVLNPVFLDG 505

Query: 97  DKLLYQAKLALDEDLRL-----------------------------KVVRKMFE--LRFG 125
                Q +L L++ ++L                             K+  K  E  L+  
Sbjct: 506 TLWNKQVELPLEQKIKLATQIIIGKLKNQLNLIKYYHKYHKDILGGKLSEKYVEVVLKID 565

Query: 126 EPAPARRSV--------EQLRGIEGSRVRATY---ALLAKQYGVTWNGRRYDPKDWEKGD 174
           +     ++          +L  IE     A +    +L    G+ +  R +        D
Sbjct: 566 KLIEKAKNYSQRNEKYTAELMAIESQAAIAYWSYIRVLTADDGIDFIRREHQ----GATD 621

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIADIIKFDTVVPKA 232
            +N  ++   + LY      ILAA   P+IG +H       + V+D+ ++ +   V    
Sbjct: 622 LLNSLLNYGYAILYARVWKNILAAKLNPSIGVLHAKQDGKPTLVFDVVELFRAQMVDRVV 681

Query: 233 FEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
             +         ++V L   D   +  +   LI  I + L  
Sbjct: 682 ISLI-------QKKVSLKMHDGLLNESSKRVLIRYILERLNR 716


>UniRef50_A0LWB2 CRISPR-associated protein Cas1 n=1 Tax=Acidothermus cellulolyticus
           11B RepID=A0LWB2_ACIC1
          Length = 295

 Score =  138 bits (349), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 49/256 (19%), Positives = 88/256 (34%), Gaps = 33/256 (12%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
            G++    GA ++ D+      +P+  VA ++  P   +  + +  AA  G  +V     
Sbjct: 14  SGEVHAAQGALLVGDE-----RVPLVDVAMMLTGPYVSLHGSVIDRAAAFGVGVVHCDWR 68

Query: 82  GVRVYA--SGQPGGARSDKLLYQAKL--------ALD--EDLRLKVVRKMFELRFGEPAP 129
           GV V A          + +   QA+L         ++  +         +  LR    A 
Sbjct: 69  GVPVAATLPWSTHNRVAARHRAQAELSLPRQKNAWMNIVKTKIRNQAAVLRALRRDGVAQ 128

Query: 130 ARRSVEQLR-----GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
             R   Q+R       EG+  R  +A L       +  + +        D +N  +    
Sbjct: 129 LERLAAQVRSGDASNAEGAAARVYWARL-------FQDKHFRRVPR-ARDVVNGLLDYGY 180

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGE 242
           + L G    A++ AG AP++G  H     P + V D+ +  +   V     EI       
Sbjct: 181 AILRGCCLRAVVGAGLAPSLGLWHRRHDNPFTLVDDLIEPFRPA-VDKTVIEIVTAGASG 239

Query: 243 PDREVRLACRDIFRSS 258
            DR  +     +    
Sbjct: 240 LDRPTKRLLVAVLDHQ 255


>UniRef50_Q7MRD4 Putative uncharacterized protein n=1 Tax=Wolinella succinogenes
           RepID=Q7MRD4_WOLSU
          Length = 314

 Score =  138 bits (348), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 57/290 (19%), Positives = 101/290 (34%), Gaps = 37/290 (12%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLE-PGTRVSHAAVRLAAQVGTL 74
           +++      + V D   V+  + G RT +P+  +  +++E P   +S A +   AQ GT 
Sbjct: 6   TVVIATSCHLRVRDRQLVIESREGERTQLPLADIGVVIVENPQVTLSAALLSALAQEGTA 65

Query: 75  LVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE---------LRFG 125
           L+    + +        G         + +    E  + +  +K+           LR  
Sbjct: 66  LMSCDSSHLPDGVFAPFGTHSRHTRAARVQAVWSEPFKKRCWQKIVRAKVSSQAEVLRRV 125

Query: 126 EPAPARRSVEQLRG---------IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
               A R +E L G         +E    +  +  L   +   W+G           D  
Sbjct: 126 GAEDAARRLENLVGKVTSGDTTGVEAQAAQVYWRSLFVNFK-RWDG---------GLDAR 175

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFE 234
           N  ++   + L G    AI  AG  PA G  H G+  SF    D+ +  +   V    + 
Sbjct: 176 NGGLNYGYAVLRGALGRAIAGAGLIPAFGLHHAGELNSFNLADDLIEPFRP-FVDLLVWG 234

Query: 235 IA--RRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAP 282
           +   R       RE R+    I   S  +       E +L+A +I   + 
Sbjct: 235 LFLERTGDDPLTREERMRIAQILGESCIMT---ERYETLLSATQIIARSL 281


>UniRef50_A1WH94 CRISPR-associated protein, Cas1 family n=5 Tax=Proteobacteria
           RepID=A1WH94_VEREI
          Length = 309

 Score =  138 bits (348), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 43/262 (16%), Positives = 89/262 (33%), Gaps = 37/262 (14%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTH---IPVGSVACIML-EPGTRVSHAAVRLAAQVGTLLV 76
               + V  G  V+ D  G R     +P+  +A ++    G   ++  +   A+ G   V
Sbjct: 11  DRRHLFVNRGFMVIKDTEGERKELGQVPLDDIAAVIANAHGLTYTNNLLVALAERGAPFV 70

Query: 77  WVGEAGVRVYASGQP--GGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP----- 129
             G     V           ++ ++  Q    L    RL     + + +  + A      
Sbjct: 71  LCGPNHNAVGMLLPLDGHHVQAKRIEAQIAAGLPMHKRLWAA--VVKSKLEQQAAALEAV 128

Query: 130 --ARRSVEQLR---------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQ 178
                 ++ L           IEG   R  + LL   +G  +       +  + GD +N 
Sbjct: 129 AAPTAPLQALVAKVRSGDPENIEGQGARRYWGLL---FGAEF-------RRDQSGDGLNA 178

Query: 179 CISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAFEIA 236
            ++   + +      A++AAG  P+IG  H+    +   V D+ +  +   V  K +++ 
Sbjct: 179 LLNYGYTIVRSACARAVVAAGLHPSIGLHHSNDANAMRLVDDLMEPFRP-IVDLKVWQLH 237

Query: 237 RRNPGEPDREVRLACRDIFRSS 258
           +        + + A   +    
Sbjct: 238 KAGESHVTPDTKRALVRVLYDD 259


>UniRef50_B5IAF4 CRISPR-associated protein Cas1 n=3 Tax=Euryarchaeota
           RepID=B5IAF4_9EURY
          Length = 404

 Score =  138 bits (348), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 43/299 (14%), Positives = 91/299 (30%), Gaps = 49/299 (16%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSV--ACIMLEPGT-RVSHAAVRLAAQVGTLLVWVGEA 81
           I+V     V+ +K           +    +++E     +S  A+R   +    +  +   
Sbjct: 13  INVDKRKLVIREKGKQVHEFYPHQINYDSLIIEGYYGNISFEAIRWLMKHNITVSVLNWN 72

Query: 82  GVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM---------------------- 119
           G  +              + Q ++ ++E  RLK+  K+                      
Sbjct: 73  GNLLSVFLPKEPINGKLKIRQYEIYINEKERLKIAEKILEEKIRKSENMLYELSEYYPEI 132

Query: 120 ----FELRFGEPAPARRSVEQ----------LRGIEGSRVRATYALLAKQYG-----VTW 160
                + R  +    +R +E           L   EG   +  +  L+K +        +
Sbjct: 133 EHIKVKKRIEKEEKLKRDMELKEENKPKLSYLLMYEGRVAQIYWKELSKIFNKLYPEFNF 192

Query: 161 NGRRYDPKDWE--KGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFV 216
             R      W     D IN  ++ + + L  +    I A G  P+IGF+H         V
Sbjct: 193 TSRSTKSYSWNMNASDEINALLNYSYALLESMIRKHINAVGLDPSIGFLHELASSKTPLV 252

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAG 275
           YD+ ++ +         ++      +    +      I    +T   L+   +  +   
Sbjct: 253 YDLQELFR-WVSDLSVIQLLEDKKLKKSSFIVTENYHIRLKPQTSKLLVEKFKLNMNKK 310


>UniRef50_A3ZPG0 Putative uncharacterized protein n=1 Tax=Blastopirellula marina DSM
           3645 RepID=A3ZPG0_9PLAN
          Length = 331

 Score =  137 bits (346), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 40/304 (13%), Positives = 95/304 (31%), Gaps = 40/304 (13%)

Query: 9   IPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRL 67
           + +  R   I  +   + +         +  +   IP   +  +++  PGT  +HAA+R 
Sbjct: 34  VLMIKRTVEISQEPFHLGLRHKQLTFKREGAVVHTIPCEEIGVVVIDHPGTTYTHAALRQ 93

Query: 68  AAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF--- 124
            A     +V  G   +                    ++   + L  ++ R++   +    
Sbjct: 94  LAASDAAVVICGANHLPAAILLPLADHSEVVWRLVEQIEAPKPLCKRLWRQIVRAKIDAQ 153

Query: 125 ----GEPAPARRSVEQLR---------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWE 171
                +  P R+ ++ L           +E    +  +     + G          +   
Sbjct: 154 ASVLPDDCPGRQKLKSLIPLVKPGDAANVEARAAKTYWQFWYPEAGF---------RRDA 204

Query: 172 KGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVV 229
             D +N  ++   +        AI++AG  PA+G  H  +   F    D+ +  +   V 
Sbjct: 205 DSDGVNALLNYGYAIARAAIARAIVSAGLTPALGLHHRNRSNPFCLADDLIEPFRP-MVD 263

Query: 230 PKAFEIARRNPGEPDREVRLACRDIFRSSKTLA-----------KLIPLIEDVLAAGEIQ 278
            +  E+ R+      +E +     +     +L            +++  +   L   +  
Sbjct: 264 ERVRELHRQGYDSLTQECKGELLKLLARQTSLDGEKGPFMVQLHRMLGSLVRCLRKKQTS 323

Query: 279 PPAP 282
              P
Sbjct: 324 LEIP 327


>UniRef50_D2R8Z2 CRISPR-associated protein Cas1 n=1 Tax=Pirellula staleyi DSM 6068
           RepID=D2R8Z2_9PLAN
          Length = 942

 Score =  137 bits (345), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 46/256 (17%), Positives = 88/256 (34%), Gaps = 34/256 (13%)

Query: 24  QIDVIDGAFVLIDKTGI-RTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           +I V         +       IP+ ++  +++     +SH  +    Q    L+ + E+ 
Sbjct: 624 EILVHGDVLQFKHQDQRGIESIPLHTLREVVVLGAVSLSHRVLSAIQQNAISLLLLDESA 683

Query: 83  VRV-YASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE-------------------- 121
            R  Y   Q     S  +  Q  L  + +  L + R++                      
Sbjct: 684 NRTAYIDCQNAEPDSAGIEAQVDLIRNPESSLAIARQLISAKLHNYATLADAYPPKSHSG 743

Query: 122 ------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDT 175
                 +R  + A    S+ +L GIEGS     Y  +  +    ++            D 
Sbjct: 744 NAHRSLMRLAKDAQQASSLPELLGIEGSGAALWYGEIGMRLSPGFH--WERRVAPNAHDP 801

Query: 176 INQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDTVVPKAF 233
           +N  ++ A + LY +T+ AI  A     +GF+H  +    +   D+ +  +         
Sbjct: 802 VNILLNLAQTVLYRMTQHAIAQAKLVDTLGFLHQPRAGHAALASDMQEPFRHLM-DRAVL 860

Query: 234 EIARR-NPGEPDREVR 248
           E  RR  P E + + R
Sbjct: 861 ETVRRIRPEEFEPDER 876


>UniRef50_Q7MTH7 CRISPR-associated protein Cas1 n=3 Tax=Porphyromonas gingivalis
            RepID=Q7MTH7_PORGI
          Length = 1031

 Score =  135 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 34/306 (11%), Positives = 79/306 (25%), Gaps = 61/306 (19%)

Query: 23   GQIDVIDGAFVLIDKTGIRTHIPVGSVACI-MLEPGTRVSHAAVRLAAQVGTLLVWVGEA 81
              I +     ++          P   +  I ++  G  +S    +   +    +++    
Sbjct: 707  AFIGISRNHVLVRKYGKTICKQPAAQIEQISIISDGVSLSSNVTKYCRKKNIRVIFYNAT 766

Query: 82   GVRVYASGQPGGARSDKLLYQAKL----------------ALDEDLRLKVVRKMFELRFG 125
            G    +           +  Q +L                  ++   L+   K +     
Sbjct: 767  GQAYASLNGMNTILPSVMEAQMRLSEEKKREFILTLIKNKVRNQGKLLRYYHKYYRHDKE 826

Query: 126  EPAPARRSVEQLRGIEG---------------------SRVRATYALLA---KQYGVTWN 161
               P   ++ +L+ +EG                        +  +   A    + G  + 
Sbjct: 827  LKEPLSNAIAELKQLEGIPIAEGSSLADFRQHAMLHEARCAQVYWRAFALLVHRSGHEFE 886

Query: 162  GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDI 219
            GR +          +NQ ++   + L       I+     P IG +H       +  +D+
Sbjct: 887  GREHK----GAEGLVNQMLNYGYAILRSYVMKTIVLWQLNPNIGILHSTQDNKPALCFDL 942

Query: 220  ADIIKFDTVVPKAFEIARRNP-------GEPDREVRLACRDIFRS-------SKTLAKLI 265
             +  +   V      +  +         G  D   R                 ++  KL 
Sbjct: 943  MEQYRAFVVDRSILALLAKGEDVGQNSKGLLDMPTRSRIISKINERWFATEYYRSGEKLF 1002

Query: 266  PLIEDV 271
              I  +
Sbjct: 1003 SDIMKL 1008


>UniRef50_B1GZM4 CRISPR-associated protein Cas1 n=1 Tax=uncultured Termite group 1
           bacterium phylotype Rs-D17 RepID=B1GZM4_UNCTG
          Length = 298

 Score =  135 bits (340), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 32/238 (13%), Positives = 79/238 (33%), Gaps = 10/238 (4%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTL 74
           ++ F +   + V +       +      IP+  ++ I+LE     ++ A +   +Q   +
Sbjct: 5   TVFFSKPCSLSVKNSQLYCRFQDSTVHDIPIEDISVIVLESNRINLTSALISECSQSNIV 64

Query: 75  LVWVGEAGVRV--YASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARR 132
           +     + +    Y         +     Q K       R+       ++        + 
Sbjct: 65  IFSCDSSHIPCGIYVPFNQHSRFTQTANSQVKWDTAFKNRIWQKIVKQKICNQAEIIKKY 124

Query: 133 SVEQLRGIEGSRVRAT----YALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLY 188
           S     G++G+  R          A    + W     + +  +  D  N  ++   + + 
Sbjct: 125 SFANYVGLKGTCDRVQSGDKTNCEAFAAKIYWESIFENFQRNKNSDIRNSALNYGYAIVR 184

Query: 189 GVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPD 244
           GV   ++ ++G+    G  H+    +F    DI +  +   V   A +I + +    +
Sbjct: 185 GVVARSLASSGFITCFGVHHSNDLNAFNLADDIIEPFRP-FVDDIAIDIFKNSETSKE 241


>UniRef50_Q9YCL8 Putative CRISPR-associated protein Cas1 n=1 Tax=Aeropyrum pernix
           RepID=Q9YCL8_AERPE
          Length = 327

 Score =  135 bits (339), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 56/310 (18%), Positives = 100/310 (32%), Gaps = 52/310 (16%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
            +I V  GA V+  K G +  +       I+      +S AAVR AA++G  LV++   G
Sbjct: 10  SRIRVARGALVVETKAGKKVVVESSVERVIISSSRVSISSAAVRAAAKMGIDLVFLDWDG 69

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE--------------------- 121
             V A   P            + + +E LR  +  ++                       
Sbjct: 70  SPV-ARLYPPIINKTVATRIGQFSANERLRRLIAAELVSAKIYNQGQTLKYIARQRADER 128

Query: 122 ---------------LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNGRR 164
                          LR  +        ++L  IE    R  +  +A+     + ++GR 
Sbjct: 129 LREAGYEVELLSGEPLRIADEDGPGF-RDKLLSIEARASRRYWQCIAEILPGRLGFSGR- 186

Query: 165 YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADI 222
               D    D  N  ++     LY + E ++L  G  P +G  H+ K    S   D  + 
Sbjct: 187 ----DRGALDPFNAALNYGYGMLYSIVEKSLLLVGLDPYLGVFHSEKSGKPSLTLDAIEP 242

Query: 223 IKFDTVVP-KAFEI----ARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEI 277
            +   V    A +      +   G  D + R        SS ++   +  +   +   + 
Sbjct: 243 FRAPIVDRILALKAGRMYLKLEAGRLDYKSRKEVAKAVASSLSMKAAVRGLGRRIRLEDA 302

Query: 278 QPPAPPEDAQ 287
                   A+
Sbjct: 303 IMVQARWLAE 312


>UniRef50_Q1WVJ8 CRISPR-associated protein n=1 Tax=Lactobacillus salivarius UCC118
           RepID=Q1WVJ8_LACS1
          Length = 301

 Score =  134 bits (338), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 46/286 (16%), Positives = 104/286 (36%), Gaps = 32/286 (11%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTL 74
           ++I  Q+ ++   + A ++ +K G    IP+  +  +++      ++ A V   A+ G  
Sbjct: 5   NVIITQHSKLSYSNNAMIVQNKDG-INQIPLVDMDILLISTTQAVITSALVSKLAESGIK 63

Query: 75  LVWVGEAGVRV-YASGQPGGARSDKLLYQAKLALDEDL--------RLKVVRKMFELRFG 125
           +++       V          RS     Q     D           R K++ ++  L+  
Sbjct: 64  VIFTDNKNEPVTETVNYYPNNRSLDTYLQQYEWNDHVKEILWTKIVRSKIINQIKVLKNY 123

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
           +       +E L  +E + +    A++A++Y     G +Y  KD+     +N  ++   S
Sbjct: 124 QIDCQDLKIE-LDKLEINDMTNREAVVARKYFEKLFGNKYSRKDFT---PMNAALNYGYS 179

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEP 243
            L       I++AGY   +G  H  +   F +  D+ +  +       A     +N  E 
Sbjct: 180 ILLSAVNKEIVSAGYVTYLGIHHQSQENMFNFGSDLMESFRPVVDYWLA----DKNFLEF 235

Query: 244 DREVRLACRDIF-----------RSSKTLAKLIPLIEDVLAAGEIQ 278
             +++    D+                 + K +  + + L    ++
Sbjct: 236 TPDIKYGLVDLLNLEIKYNKKQMLLKNAITKYVRDVIEYLNQETVE 281


>UniRef50_A1ZHZ5 Crispr-associated protein Cas1 n=1 Tax=Microscilla marina ATCC
           23134 RepID=A1ZHZ5_9SPHI
          Length = 344

 Score =  134 bits (337), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 57/296 (19%), Positives = 94/296 (31%), Gaps = 56/296 (18%)

Query: 23  GQIDVIDGAFVLIDKTGIRTH------IPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
             + V +  F +  K            I   +V  I L  GT VS  A+ LA      +V
Sbjct: 13  AYLQVKNQMFCIRTKNAKTREYHAHAPIAPHTVHRIFLHRGTAVSVDAMHLALINNIDIV 72

Query: 77  WVGEAGVRVYASGQPGGARSDKLL-------------YQAKLALDEDLRLKVV------- 116
            +      +          + K+                 K  L   L  ++        
Sbjct: 73  LMQHDDHPIGRVWHTKLGSTTKIRKKQLEASLNEVGTAWVKQWLSTKLGNQIAMIEQLKK 132

Query: 117 ----RKMFELRFGEPAPARRS-------------VEQLRGIEGSRVRATYALLAKQYG-- 157
               ++ +     +   A ++              + LRG+EG+  R  +  L+      
Sbjct: 133 HRESKRTYLHEKADKIRALQTSIEALEADHTEAIADTLRGLEGTAGRLYFETLSYVLAKE 192

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSF 215
             + GR   P      D  N  ++     LY + E A++ AG  P +GF+H       S 
Sbjct: 193 YQFAGRSKRP----AHDAFNAFLNYGYGILYSMVEHALVIAGIDPFVGFMHRDGYNQRSM 248

Query: 216 VYDIADIIKFDT--VVPKAFEIARRNPGEPD---REVRLACRDIFRSSKTLAKLIP 266
           VYD  +  +     VV K F   + N    D     VRL        ++ L K + 
Sbjct: 249 VYDFIEPYRGHVEQVVVKLFTAKKVNQSHTDAIKDGVRLNEMGKPLLTEALGKYLR 304


>UniRef50_Q8TVS6 Uncharacterized conserved protein n=1 Tax=Methanopyrus kandleri
           RepID=Q8TVS6_METKA
          Length = 331

 Score =  134 bits (337), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 55/329 (16%), Positives = 102/329 (31%), Gaps = 56/329 (17%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           ++IFL+ G+I+  + AF +      ++         I++  G +++  AVRLA +    +
Sbjct: 7   TVIFLRRGKIERREDAFRI-----GKSKYSAVRTTGIIIAGGAQITTQAVRLALRNEVPI 61

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF----------- 124
           V++G   +            +   L Q ++A     RL   R +                
Sbjct: 62  VYLGGNRILGVTVPFSE-RYATLRLKQYEIASQPSARLAFARPLIASSILARAAVLEFLA 120

Query: 125 ------------------GEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYD 166
                              E A    S + LRG EG      +  LA+     W      
Sbjct: 121 NETGITGLEDAADEVRSEAERALNAGSTDALRGYEGRAACRYFRALAEVLP-DWAF-SGR 178

Query: 167 PKDWEKGDTINQCISAATS-CLYGVTEAAILAAGYAPAIGFVH--TGKPLSFVYDIADII 223
                  D  N  IS   +  L  V  +  +AAG  P +GF+H   G+    + D+ +  
Sbjct: 179 RTRRPPRDPFNAAISFGYAGVLLPVLLSRTVAAGLEPFLGFLHGPRGRRPGLILDLMEEW 238

Query: 224 KFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSS-------------KTLAKLIPLIED 270
           +   V               +   R     +                 +    L+  ++ 
Sbjct: 239 RALAVDVPVLRRFLDGSLSREM-FRWKGDAVLLRDLDAVSAPVLTVLSRVRGGLLEAVDR 297

Query: 271 VLAA--GEIQPPAPPEDAQPVAIPLPVSL 297
            +      +   +PPE  +     + V  
Sbjct: 298 RIREVRDGVSRQSPPEPLEFDPEDVGVVW 326


>UniRef50_B1L400 CRISPR-associated protein Cas1 n=2 Tax=Archaea RepID=B1L400_KORCO
          Length = 341

 Score =  133 bits (336), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 43/258 (16%), Positives = 85/258 (32%), Gaps = 48/258 (18%)

Query: 25  IDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
           +    G  +++ K G +  IP+ SV  +++     +S   ++  AQ GT L+     G  
Sbjct: 18  LRKRRGRILILSK-GEKKEIPMKSVKEVVIIGKAALSSELLKALAQSGTDLLIATPTGRP 76

Query: 85  VYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMF----------------ELRFGEPA 128
           V          + +  Y+   +L++   +++ R +                   R  E  
Sbjct: 77  VARLIPAKAGGTARNRYEQYKSLEDRRGIEIARAVIVGKIRNQASNLSYYSKARRMDEEL 136

Query: 129 PARR------------------------SVEQLRGIEGSRVRATYALLAKQYGVTWNGRR 164
            +                          + +++   E       +  +A      W  R 
Sbjct: 137 SSELYDAAQQLKREMEELKNEEFPDIDEARKRIMARESKCANIYWEKIASIM-EEWKFRG 195

Query: 165 Y-DPKDWEKG--DTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDI 219
                D E    D +N C++   + L       +L  G  P +G++H  +P   S VYD+
Sbjct: 196 REKRTDLEGNVIDPVNLCLNVCYNLLSAQIWKNVLRFGLDPFLGYLHVERPGRISLVYDL 255

Query: 220 ADIIKFDTVVPKAFEIAR 237
            +  +   V    F   R
Sbjct: 256 MEPFRP-MVDRFVFSYLR 272


>UniRef50_Q5X8T5 Putative uncharacterized protein n=1 Tax=Legionella pneumophila
           str. Paris RepID=Q5X8T5_LEGPA
          Length = 330

 Score =  133 bits (336), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 39/261 (14%), Positives = 75/261 (28%), Gaps = 44/261 (16%)

Query: 26  DVIDGAFVLIDKTGIRTHIPVGSVACI-MLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVR 84
            +     ++ +K  +     +  +  I +++ G  ++   +   A  G  +  +  +G  
Sbjct: 14  KLQGERILVFNKDQMVFEGTLNRLKTISIVKQGVTLTSNLLVACAMRGIQIFILDYSGKA 73

Query: 85  VYASGQPGGARSDKLLYQAKL-----ALDEDLR-------------LKVVRKMFELRFGE 126
           V +        +     Q K      A +   R                 +        +
Sbjct: 74  VCSLQGGLHRTAKVRESQFKYIYTKEASNMAARFILAKIKKQSAVLKYFAKAKNRPENEK 133

Query: 127 PAPARRSVE---------------------QLRGIEGSRVRATYALLAKQYGVTWNGRRY 165
                 S +                      L G EGS  R  +  + +   V  +    
Sbjct: 134 IILHAASQKMAGIVANITETNWIKLQDWRFTLLGFEGSAARIYWETVKEVNLVCSDFEGR 193

Query: 166 DPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADII 223
            P      D  N  ++ A S L      AI  AG     G +HT KP   S V D+ +  
Sbjct: 194 RP--RVNKDITNSMLNYAYSILSSWVWQAITNAGLELYAGILHTSKPGKPSLVLDLMEEF 251

Query: 224 KFDTVVPKAFEIARRNPGEPD 244
           +        F++  R   + +
Sbjct: 252 RPWCADRIIFKLHARAQKQNE 272


>UniRef50_C9RJP2 CRISPR-associated protein Cas1 n=21 Tax=cellular organisms
           RepID=C9RJP2_FIBSS
          Length = 298

 Score =  132 bits (332), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 34/279 (12%), Positives = 82/279 (29%), Gaps = 37/279 (13%)

Query: 14  RVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVG 72
           + ++ F     + + D   V+  +        +  +A I+L  P   V++A +    +  
Sbjct: 3   KRTLYFGNQAYLSLKDNQLVIKKRNDEIVTAAIEDIAYIVLDSPQITVTNALLGALLENN 62

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF-------- 124
             ++   +  +         G       +QA++     L+ ++ ++  + +         
Sbjct: 63  CAIINCDKTHLPSGLLLPLSGNTLQSERFQAQIDASLPLKKQLWQQTVQQKILNQAAVLH 122

Query: 125 ----GEPAPARRSVEQLR-----GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDT 175
                E          +R       E       +  +          R   P        
Sbjct: 123 GSHDAEIGNMTAWANSVRSGDVDNREAVAAAYYWKEMFPDIPDFVRDRNGVPP------- 175

Query: 176 INQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKAF 233
            N  ++   + L GV   A++++G  P +G  H  +  +     DI +  +   V     
Sbjct: 176 -NNMLNYGYAILRGVVARALVSSGLLPTLGIHHHNRYNAYCLADDIMEPYRP-IVDKLIL 233

Query: 234 EIARRNPGEPD--------REVRLACRDIFRSSKTLAKL 264
           E+       P         + +R+   D          +
Sbjct: 234 EVINEIEEYPTDLSTEIKAKLLRIPVLDCVIDGNRSPLM 272


>UniRef50_A2SQK9 Uncharacterized protein predicted to be involved in DNA repair-like
           protein n=1 Tax=Methanocorpusculum labreanum Z
           RepID=A2SQK9_METLZ
          Length = 310

 Score =  131 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 43/277 (15%), Positives = 88/277 (31%), Gaps = 34/277 (12%)

Query: 33  VLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRV---YASG 89
           +++ + G  T  P+  +  +++  G  +  + +   A  G  + +    G  V   Y  G
Sbjct: 21  LIVRQKGSTTQYPLDDMRHLLIAGGHSLHTSVLERLADRGIAVSFFTAHGKPVGGIYGKG 80

Query: 90  QPGGARSDKLL-----YQAKLALDEDLRLKVVRKMFELR------FGEPAPARRSVEQL- 137
            P  A   + +       A +    D RL+ + ++ E         GE      + E+L 
Sbjct: 81  APSLASQQRDIPIHKFAMASIRSSLDERLRYINELAEFDPEGLYFKGEFDILTAAREELE 140

Query: 138 -------RGIEGSRVRA-TYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
                   G   S  +   Y ++ ++       R          D +N  +S   + LY 
Sbjct: 141 YLITLPEIGRAFSLTKTMYYEIIGRKLPKVLGYR--RRCQPPFMDPVNVMMSHGYAVLYA 198

Query: 190 VTEAAILAAGYAPAIGFVHT------GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGE- 242
               A   AG   + G ++       G     V D+ +      V     ++A     + 
Sbjct: 199 NFALACTGAGLDLSRGALYGEIVSAPGGRGGCVLDLMEPATVSMVDRVIIQMAAEGRLDG 258

Query: 243 -PDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQ 278
             +   R    +     + + +L   I   L    + 
Sbjct: 259 AYEVTTRCLLSNE-LKEEFMKRLHGSINITLIEENVN 294


>UniRef50_A2BKJ8 Universally conserved protein n=1 Tax=Hyperthermus butylicus DSM
           5456 RepID=A2BKJ8_HYPBU
          Length = 331

 Score =  131 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 47/279 (16%), Positives = 83/279 (29%), Gaps = 49/279 (17%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGV 83
           +I V  G       +G +  +   +   ++      VS  A+R  A++G  LV +G+ G 
Sbjct: 13  RIYVRRGVVYAEAPSGEKAVVTADTELVVLATGSVSVSGRALRRLAELGVRLVVLGQRGQ 72

Query: 84  RVYASGQPG--GARSDKLLYQAKLALDEDLRLKVVRKMFEL------------------- 122
            V             +  + Q ++    +        ++                     
Sbjct: 73  VVAEHRPVDRVNRTIEARMEQYRVKATGEALYYAAEMVYAKIVNQAKLLRYLAKSRREPW 132

Query: 123 -------------RFGEPAPAR--RSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDP 167
                        R  +        + E +R IE    R  +  +A+     + GR    
Sbjct: 133 LRDAGYRVEGHADRLRQIIENEEPTTPEVIRSIEAQAARDYWDAIAQIAPTPFPGR---- 188

Query: 168 KDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKF 225
                 D +N  +S   + LY +   A+  AG  P  GF+H  +    S  YD AD  K 
Sbjct: 189 -QPRGEDHLNMALSYGYAILYSIAHDALTVAGLDPYAGFLHADRSGRPSLTYDYADTYKP 247

Query: 226 DTVVPKAFEIARR------NPGEPDREVRLACRDIFRSS 258
             V        R+        G      R     +   +
Sbjct: 248 IAVDKPLLTAPRKTDCLDTYMGALTYNARRCIATLVLEN 286


>UniRef50_B2KB47 CRISPR-associated protein Cas1 n=2 Tax=Elusimicrobia
           RepID=B2KB47_ELUMP
          Length = 298

 Score =  131 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 25/225 (11%), Positives = 69/225 (30%), Gaps = 31/225 (13%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTLLVWVGEAG 82
            + V +  F  +     + H     +  I+L      +S+  ++   +    +++  +  
Sbjct: 13  HLCVKNNNFSAVKDREEKLHCLFDDINSIILYGNNITISNTCIQKCLEHKVPVIFCDKTY 72

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRG--- 139
                              Q ++   +    +  +++   +    A   +  + L+    
Sbjct: 73  NPAGMLLSSFTTNIYGRRLQLQINASKPQIKQAWQQIITSKLNNQAEVLKRFDTLKAAET 132

Query: 140 ---------------IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
                           EG   +  +  L   +           ++ +  D IN  ++   
Sbjct: 133 IFNMAREVRSGDATFKEGVGAKVYFENLFNDFH----------RNTDDKDIINSALNYGY 182

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDT 227
           + +      A+++AG  PAIG  H+     F    D+ + ++   
Sbjct: 183 AIVRSSIARAVVSAGLNPAIGIFHSKNHNPFCLIDDLIEPLRPLI 227


>UniRef50_B9M9X7 Putative uncharacterized protein n=1 Tax=Diaphorobacter sp. TPSY
           RepID=B9M9X7_DIAST
          Length = 302

 Score =  131 bits (330), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 38/264 (14%), Positives = 85/264 (32%), Gaps = 25/264 (9%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVGTL 74
           S++  +  ++     A V+  +      +P   +A I+L      ++H  +    + G  
Sbjct: 5   SIVINRPAKLKREHFALVVEQEQ--SARVPFEDIAVIVLNHREITLTHPVLSACGEYGIG 62

Query: 75  LVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSV 134
           L   G+                   + + +L LD+    +    + +++ G  A      
Sbjct: 63  LYSTGDNHQPNGVFMPFLQHSRATRMQRLQLDLDKPSAKRAWAHIVQVKIGNQARCM--- 119

Query: 135 EQLRGIEGSRVRATYA-------------LLAKQYGVTWNGRRYDPKDWEKGDTINQCIS 181
            +L G  G+   A+YA               +  Y     GR +           N  + 
Sbjct: 120 -ELLGTVGTDRLASYARRVRSGDGGNLEAQASAYYFPQVFGRSFHRSQTGWS---NAALD 175

Query: 182 AATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRN 239
              + + G    A++A G  P++G  H  +  +F    D+ +  +    +  A       
Sbjct: 176 YGYAVMRGACARALVAHGMLPSLGLFHRSEQNAFNLADDLIEPYRPVVDLHVAQHRPADE 235

Query: 240 PGEPDREVRLACRDIFRSSKTLAK 263
             E     ++A   +      + +
Sbjct: 236 DAELQPSDKVALVGLLNVDVAMPR 259


>UniRef50_C7V674 Predicted protein n=2 Tax=Enterococcus faecalis RepID=C7V674_ENTFA
          Length = 304

 Score =  131 bits (329), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 40/294 (13%), Positives = 92/294 (31%), Gaps = 46/294 (15%)

Query: 17  MIFLQYG-QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTL 74
            +F++ G ++ V      +I + G    IP+  +  ++LE   T ++   +   AQ    
Sbjct: 5   TVFVKNGEKLKVKLDNLEVIKE-GNTYVIPLTDIESVILEGDQTVITTRLLAKFAQHHID 63

Query: 75  LVWVGEAGVRV--YASGQPGGARSDKLL------------YQAKLALDE-DLRLKVVRKM 119
            V      + V  +         + + +               ++   +   ++ V + +
Sbjct: 64  TVICDNTFMPVGVFLGIGQYHRSAKRAIWQSNWTEEHKQVAWCEIVTQKIQNQIAVAKYL 123

Query: 120 FELRFGEPAPARRSVEQLRG----IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDT 175
                      + S   L G     EG   +  +  L   YGV +          E+   
Sbjct: 124 GTDSERVEVLEKLSEGILPGDTTNREGHVAKVYFHSL---YGVGFT--------REEECL 172

Query: 176 INQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAF 233
            N C++   + +       ++A G  P +G  H  +  SF    D+ +  +         
Sbjct: 173 PNACMNYGYAVIRAQMARCVVALGLLPMLGIFHKNEYNSFNLVDDLMEPFRPLMDWYIHQ 232

Query: 234 EIARRNPGEPDREVRLACRDIFRSS-----------KTLAKLIPLIEDVLAAGE 276
            I ++N        RL   +                + +++ +      +  G+
Sbjct: 233 TILKKNEKYLTYHSRLTLVEFLHQKIKVKNKKIYMNQAMSEYVAAFVKAMETGD 286


>UniRef50_Q13CC1 CRISPR-associated protein, Cas1 family n=2 Tax=Rhodopseudomonas
           palustris RepID=Q13CC1_RHOPS
          Length = 299

 Score =  130 bits (328), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 45/279 (16%), Positives = 87/279 (31%), Gaps = 47/279 (16%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTR 59
           M W  L+             Q  ++ + D    +    G    + +  +A I++  P   
Sbjct: 1   MAWRGLHLT-----------QAARLSLADSQVCVKQDAGE-VRLALEDIAWIVIDTPQAT 48

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYAS--GQPGGARSDKLLYQAKLALDEDLRLKVV- 116
           ++ A +    + G +LV+  E       +        +      Q         RL    
Sbjct: 49  LTSALMSACMEAGIVLVFTDERHTPSGMALPFHRHHRQGGIARLQMDAKDGVKKRLWQAI 108

Query: 117 --RKMFELRFGEPAPARRSVEQLR------------GIEGSRVRATYALLAKQYGVTWNG 162
             RK+           R + E LR             +E    R  +  L + +      
Sbjct: 109 IRRKILNQAGSLAVLDRNNAETLREIARHVEPGDPENVEARAARFYWGRLFEDF------ 162

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIA 220
                   + GD  N+ ++   + +      A++A+G+ PA G  H G   +F    D+ 
Sbjct: 163 -----VRDDDGDLRNKMLNYGYAVVRAGVARALVASGFLPAFGLKHDGAANAFNLADDLV 217

Query: 221 DIIKFDTVVPKAFEIAR---RNPGEPDREVRLACRDIFR 256
           +  +   V   A++         G+   E R A   +  
Sbjct: 218 EPFRP-FVDVLAWKTLGDRVDRKGDLTLEDRRAMAGVLL 255


>UniRef50_B2UP48 CRISPR-associated protein Cas1 n=1 Tax=Akkermansia muciniphila ATCC
           BAA-835 RepID=B2UP48_AKKM8
          Length = 311

 Score =  130 bits (327), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 38/255 (14%), Positives = 66/255 (25%), Gaps = 34/255 (13%)

Query: 23  GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLVWV--- 78
             +    G     D       IP+  V  ++L      ++   +   A+     V     
Sbjct: 13  CHLSCDKGQLRCADGENSPRTIPLEDVGAVVLSSFKATLTSNLLIELARKRIGFVLCESY 72

Query: 79  ------------GEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE 126
                        + G+  + +  P   R+                L            E
Sbjct: 73  RPAVLLLPADRSTDTGLLRHLADMPARLRNRLWQKTLDAKCGNQTALAQAWNPHHPAIAE 132

Query: 127 PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSC 186
                 + +  R  E    R  +++ A     TW    +     E+G   N   + A + 
Sbjct: 133 LKRMAVTEKTAR--EAECARLFWSVFAD----TWANSDFRRGRHEEG--FNNLFNYAYAI 184

Query: 187 LYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDT---VVPKAFEIARRNP- 240
           L       + A G  P  G  H  +  +    YD+ +  +      V        R    
Sbjct: 185 LLSCILQYLFALGLDPCFGIFHQSREHAAPLAYDLMEPFRPAFDANVARWIHLCLREGKT 244

Query: 241 ----GEPDREVRLAC 251
               GE  RE R   
Sbjct: 245 EERAGEITREFRQHI 259


>UniRef50_A8TI31 CRISPR-associated protein Cas1 n=1 Tax=Methanococcus voltae A3
           RepID=A8TI31_METVO
          Length = 235

 Score =  130 bits (326), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 30/203 (14%), Positives = 62/203 (30%), Gaps = 27/203 (13%)

Query: 98  KLLYQAKLALDEDLRLKVVRKM--------------FELRFGEP-----APARRSVEQLR 138
            ++ Q++  L+ D R  + ++               ++L + +            +  + 
Sbjct: 1   MIVQQSENYLNSDKRHYIAKEFVKGSILNISKNLSRYKLDYDKEKYITALQKVNRITDIM 60

Query: 139 GIEGSRVRATYALLAKQYG-VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILA 197
            +E       Y      +    +  R   P + E    IN  IS   S LY    + I  
Sbjct: 61  NVEALMRNDYYNNFDNIFKNFKYEKRSRRPPENE----INALISFGNSLLYSTVISEIFN 116

Query: 198 AGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIF 255
               P++ ++H    +  S   DIAD+ K   V    F +  +     +           
Sbjct: 117 THLNPSVSYLHEPYERRYSLALDIADVFKPIFVDRLIFNLVNKKIIN-ENHFEKDLNSCL 175

Query: 256 RSSKTLAKLIPLIEDVLAAGEIQ 278
            + +  A  +    + L      
Sbjct: 176 LNDEGRAIFLSKYNERLQKTIKH 198


>UniRef50_A8LN06 CRISPR-associated protein Cas1 n=2 Tax=Rhodobacterales
           RepID=A8LN06_DINSH
          Length = 303

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 43/262 (16%), Positives = 84/262 (32%), Gaps = 30/262 (11%)

Query: 13  DRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLE-PGTRVSHAAVRLAAQV 71
           D++  I      +    G   + +       IP+  +A +++   GT  + + +   A  
Sbjct: 2   DQIVDIATDGRHLSRDRGFLKVSEGAREIGRIPLDQIAGVIVHAHGTTWTTSLLTELADR 61

Query: 72  GTLLVWVGEAGVRVYASGQP--GGARSDKLLYQ----AKLALDEDLRLKVVR-KMFELRF 124
           G  +V  G                A+  +L  Q    A L      +  + +  M     
Sbjct: 62  GAPVVLCGANHAPRSVLMPLDGHHAQGARLRAQWQARAPLVKQAWKQTVIAKIAMQAAAL 121

Query: 125 GEPAPARRSVEQLR---------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDT 175
                    V  L           +E    R  +    +  G  +       +D    D 
Sbjct: 122 EAMGEPHAPVGMLARKVTSGDATNVEAQAARLYW---PRMMGTEF------RRDRTAPD- 171

Query: 176 INQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAF 233
           +N  ++   + L   T  A++AAG  P IG  H+ +  +F    D+ +  +   V     
Sbjct: 172 LNALLNYGYTVLRAATARAVVAAGLHPTIGLHHSNRGNAFALADDLMEPFRP-LVDCCVR 230

Query: 234 EIARRNPGEPDREVRLACRDIF 255
            +A RN  + D   + +   + 
Sbjct: 231 GLAARNGPQVDPAAKQSLARLI 252


>UniRef50_A6DE65 Putative uncharacterized protein n=1 Tax=Caminibacter
           mediatlanticus TB-2 RepID=A6DE65_9PROT
          Length = 267

 Score =  128 bits (323), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 30/239 (12%), Positives = 74/239 (30%), Gaps = 41/239 (17%)

Query: 65  VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF 124
           +    +    + +V               +     + Q ++  + + R++  R+  + + 
Sbjct: 2   IYALQKRKISIEFVDYKYNPYAMIYGIELSYPKIAIKQLEIV-NSEKRIEFAREFVKAKI 60

Query: 125 GEPAP---------------------------ARRSVEQLRGIEGSRVRATYALLAKQYG 157
                                               +++L G EGS     +  ++K   
Sbjct: 61  VNQRNYLKIMSKYHKNLEENIIKIDKIKSKIKNANKIDELMGYEGSIANIYWNGISKIL- 119

Query: 158 VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT-GKPLSFV 216
              N   +        D IN  ++   + LY   + A++ AG    I F+HT  K    V
Sbjct: 120 ---NEEDFKRITKGATDRINTALNYGYAILYNKVQKALIKAGLGINISFLHTFEKKPVLV 176

Query: 217 YDIADIIKFDTVVPKA-FEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAA 274
           +D  +  +   V     F + + +  + +            + +   +++  + + LA 
Sbjct: 177 FDFIEQFRCVAVDKAICFSLKKSDDIDVN-------NKGMLTREAKRRIVEEVNERLAT 228


>UniRef50_A6VLA8 CRISPR-associated protein Cas1 n=13 Tax=Proteobacteria
           RepID=A6VLA8_ACTSZ
          Length = 305

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 35/318 (11%), Positives = 91/318 (28%), Gaps = 57/318 (17%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TR 59
           MTW     I +           G++ +     ++  + G    +P+  +A +++E   T 
Sbjct: 1   MTW---RSILMSK--------GGKLSLQQNQMLIQ-QEGNEFTVPLEDIAIVVVESRETV 48

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYASGQ--PGGARSDKLLYQAKLALDEDLRLKVVR 117
           ++   +      G   +   E  +             +   L  Q + +L +  +L    
Sbjct: 49  ITIPLLSAFGLHGVTFLTCDEQFLPCGQWLPFNQYHRQLKTLKLQLEASLPQKKQLWQAI 108

Query: 118 KMFELR----------FGEPAPARRSVEQLR------GIEGSRVRATYALLAKQYGVTWN 161
              ++R          F   +     + +         +E       +  L         
Sbjct: 109 VQQKIRNQAGVLKICKFQAESDRLLKMAEKVKSGDKENLEAQSAVIYFQTL--------F 160

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DI 219
           G+ +   + E    +N  ++   + +      A++  G+ P IG  H  +  +F    D 
Sbjct: 161 GKGFKRSEDES--AVNSALNYGYTVMRSAVARALVLYGWLPQIGLFHRSELNAFNLADDF 218

Query: 220 ADIIKFDTVVPKAFEIARRNPG--EPDREVRLACRDIFRSS-----------KTLAKLIP 266
            +  +   V     ++   +         ++     +                 + + + 
Sbjct: 219 IEPFRP-LVDLLVVQLENEDKLSANLSPILKQRLIKVLNYQLLFKQEKVNALTAIERSVG 277

Query: 267 LIEDVLAAGEIQPPAPPE 284
             +  L+         PE
Sbjct: 278 SFQTALSQRNADLLKLPE 295


>UniRef50_C0WRP8 CRISPR-associated protein n=18 Tax=Lactobacillaceae
           RepID=C0WRP8_LACBU
          Length = 327

 Score =  127 bits (319), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 45/252 (17%), Positives = 88/252 (34%), Gaps = 21/252 (8%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTL 74
           S+I  Q+ ++       ++    G    IP+  ++ +++      ++ A +   AQVGT 
Sbjct: 31  SVIITQHAKLSYSSHMMIVQTNDG-INQIPIDDISILLISTTRAVITTALISELAQVGTK 89

Query: 75  LVWVGEAGVRV--YASGQPGGARSDKLLYQAKLALDEDLRLK---VVRKMFE----LRFG 125
           +++   A   +       P       L  Q          L    V  KM      L F 
Sbjct: 90  VIFTDGANQPICETVGYYPNNRSVKLLQEQVNWDEQRKEVLWTKIVASKMINQVNVLTFY 149

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
           +      + E+L  +E +      A++A++Y        +  ++      IN  +    S
Sbjct: 150 KKDTTEVN-EELAKLEVADPSNREAVVARKYFPLLFNNDFSRRNGSA---INAALDYGYS 205

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEP 243
            L       I++ GY   IG  H G+   F    D+ +  +        F IA +   + 
Sbjct: 206 ILLSSINQEIVSNGYLTYIGIHHRGEDNPFNLGSDLMEPFRPVVD----FWIASQKFDQL 261

Query: 244 DREVRLACRDIF 255
             +V+     + 
Sbjct: 262 TPDVKYGLVQLL 273


>UniRef50_B4AQ39 Crispr-associated protein Cas1 n=5 Tax=Francisella
           RepID=B4AQ39_FRANO
          Length = 334

 Score =  126 bits (317), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 38/259 (14%), Positives = 74/259 (28%), Gaps = 40/259 (15%)

Query: 19  FLQYGQIDVIDGAFVLIDK--TGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLV 76
                ++ +  G  V+ DK    ++T + V  V  + +     ++   +    +    LV
Sbjct: 17  IFDGVKLSLSLGNIVIKDKETDEVKTKLSVHKVLALFIVGNMTMTSQLLETCKKNAIQLV 76

Query: 77  WVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE---------- 126
           ++  +       G    A       Q  +   +   + + R     +             
Sbjct: 77  FMKNSFRPYLCFGDIAEANFLARYKQYSVVEQD---ISLARIFITSKIRNQHNLVKSLRD 133

Query: 127 -----------------PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD 169
                                  S+ +L GIEG+  +  +         +W GR    K 
Sbjct: 134 KTPEQQEIVKKNKQLIAELENTTSLAELMGIEGNVAKNFFKGFYGHLD-SWQGR----KP 188

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDT 227
             K D  N  +    S L+   E  +   G+    GF H    K  S V D  +  +   
Sbjct: 189 RIKQDPYNVVLDLGYSMLFNFVECFLRLFGFDLYKGFCHQTWYKRKSLVCDFVEPFRC-I 247

Query: 228 VVPKAFEIARRNPGEPDRE 246
           V  +  +         +  
Sbjct: 248 VDNQVRKSWNLGQFSVEDF 266


>UniRef50_C6MJ62 CRISPR-associated protein Cas1 n=5 Tax=Nitrosomonas sp. AL212
           RepID=C6MJ62_9PROT
          Length = 430

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 40/264 (15%), Positives = 86/264 (32%), Gaps = 40/264 (15%)

Query: 18  IFLQYGQIDVIDG-AFVLIDKTGIRTHIPVGSVACIMLEPGT-RVSHAAVRLAAQVGTLL 75
           + ++ GQ+ +  G +   + +   R    V +V  I++   T  +S AA++  +     L
Sbjct: 122 LQVEKGQLVLRSGYSCSTVTEREKRITRGVHAVRAIIVINTTGNLSTAAIQWCSDQRIAL 181

Query: 76  VWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRF----------- 124
             +         +  P          Q  +       L + +++   +F           
Sbjct: 182 YVLDRDAHLTALTHAPTPHVVSLRRLQYSV-----ETLTLAKEILYRKFDACIKCMPILA 236

Query: 125 ------GEPAPARRSVEQLRGIEGSRVRATYALLA--------KQYGVTWNGRRYDP--- 167
                  +      ++E++R IE       ++           K   + W G        
Sbjct: 237 QSFTQSADSILYANTLEEMRLIEARAAIIYWSTWNNCVIKWKEKDVPIEWRGFSQRASGI 296

Query: 168 --KDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADII 223
             K ++    +N  ++ A + L G  E A+   G   A+G +H  +    S VYD+ + +
Sbjct: 297 SGKGYKATHPVNAILNYAYAILAGQVERALQIVGLDVAVGSLHADQDGRASLVYDLMEPL 356

Query: 224 KFDTVVPKAFEIARRNPGEPDREV 247
           +   +    F             V
Sbjct: 357 RP-VIDKIIFAWVTSQQWRRADFV 379


>UniRef50_Q03LF6 CRISPR-associated protein, Cas1 family n=6 Tax=Streptococcus
           RepID=Q03LF6_STRTD
          Length = 303

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 38/278 (13%), Positives = 90/278 (32%), Gaps = 44/278 (15%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTR 59
           MTW  ++    +           ++ + +   +L+ K G    +P+  ++ I+     T 
Sbjct: 1   MTWRVVHVSQSEKM---------RLKLDN---LLVQKMGQEFTVPLSDISIIVAEGGDTV 48

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVR--VYASGQPGGARSDKLLYQAKLALDEDLRLKVVR 117
           V+   +   ++    LV      +   +Y S         +L  Q   +  +  +   + 
Sbjct: 49  VTLRLLSALSKYNIALVVCDNEHLPTGIYHSQNGHFRAYKRLKEQLDWSQKQKDKAWQIV 108

Query: 118 KMFELRFGEPAPA--RRSVEQLR---------------GIEGSRVRATYALLAKQYGVTW 160
             +++   E   A   +S++ +R                 EG   +  +  L        
Sbjct: 109 TYYKINNQEDVLAMFEKSLDNIRLLSDYKEQIEPGDRTNREGHAAKVYFNEL-------- 160

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYD 218
            G+++     ++ D IN  ++   + +       +   G    +G  H       + V D
Sbjct: 161 FGKQFVRVTQKEADVINAGLNYGYAIMRAQMARIVAGYGLNGLLGIFHKNEYNQFNLVDD 220

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFR 256
           + +  +   V    ++  R        E RL   D+  
Sbjct: 221 LMEPFR-QIVDVWVYDNLRDQEF-LKYEYRLGLTDLLN 256


>UniRef50_C3WD45 CRISPR-associated protein cas1 n=1 Tax=Fusobacterium mortiferum
           ATCC 9817 RepID=C3WD45_FUSMR
          Length = 327

 Score =  123 bits (309), Expect = 7e-27,   Method: Composition-based stats.
 Identities = 40/295 (13%), Positives = 93/295 (31%), Gaps = 45/295 (15%)

Query: 18  IFLQY--GQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLL 75
           +F+Q    +I      FV+  K   + +     +  I+++ G +++   +    +    L
Sbjct: 3   LFVQKNGSKIYREKEYFVVERKEEGKEYFSYNLIDNIIIQEGNQLTSDFLLEIIEKDIPL 62

Query: 76  VWVGEAGV-RVYASGQPGGARSDKLLYQAKLALDE--------------DLRLKVVRKMF 120
               + G  R   +       S+    Q +L + E              + + K ++K++
Sbjct: 63  YLGDKYGNIRGKFTPITYNTNSNIRERQYQLWIREYGKELGKSWIMEKIENQKKHIQKIY 122

Query: 121 ELR------------FGEPAPARRSV--------EQLRGIEGSRVRATYALLAKQYGVTW 160
             R            F E     +++         ++ G EG      Y  + K     W
Sbjct: 123 SRRGVLDKFLEIERKFDENITKIKNITWNDKDFENRVMGYEGRSSILYYEEIKKFLPENW 182

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYD 218
           +      +     +  N  ++ A   LY   E  +  AG    +G +H+      S ++D
Sbjct: 183 SF--TKRETQGAKEPYNIVLNYAFGILYFKLERYLTLAGLDIQLGIIHSNNNKSNSLIFD 240

Query: 219 IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
             +  +       AF +  +     +        +     +    +   + + L 
Sbjct: 241 FIEPFR-ILAWECAFSLFSKKELNKNYF---NLNEGKIELEGKRVIAKDLYNRLK 291


>UniRef50_B8I084 CRISPR-associated protein Cas1 n=1 Tax=Clostridium cellulolyticum
           H10 RepID=B8I084_CLOCE
          Length = 298

 Score =  123 bits (309), Expect = 7e-27,   Method: Composition-based stats.
 Identities = 27/251 (10%), Positives = 73/251 (29%), Gaps = 35/251 (13%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTL 74
           ++I     ++ +      +    G    IP+  +  I+L+     ++ A +   A+    
Sbjct: 5   NIIVSNPTKLKLKQNNLWVEQSDG--FSIPIDDINTIVLDSADVTITSALLSKLAEEDIA 62

Query: 75  LVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP-----AP 129
           L                        + + ++ L    + +  +++ + +           
Sbjct: 63  LYSCDGKHTPNGVLLPFSCHSRQYKIVKTQINLSAPFKKRCWQRVVQQKIENQAFCLNIL 122

Query: 130 ARRSVEQLRGI------------EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTIN 177
             +  ++L  +            E    +  +++L   +                 D  N
Sbjct: 123 ELKGRDELINLSKSVLSGDSTNVEAHAAKYYFSVLFTNF------------KRGMQDNTN 170

Query: 178 QCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEI 235
             ++   S L G     I + G+ P+IG  H  +  +F    D  +  +   V     + 
Sbjct: 171 YALNYGYSILRGAVARTIASYGFIPSIGIHHRSELNNFNLADDFIEPFRP-IVDMWVKQN 229

Query: 236 ARRNPGEPDRE 246
              +     + 
Sbjct: 230 INEDTLLTPKH 240


>UniRef50_C6HZN2 CRISPR-associated protein Cas1 n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HZN2_9BACT
          Length = 245

 Score =  123 bits (308), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 42/245 (17%), Positives = 82/245 (33%), Gaps = 46/245 (18%)

Query: 15  VSMIFLQYG--QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVG 72
           ++ ++L      +DV +G+ +L ++      IP+  +  +++     +S A +   ++ G
Sbjct: 1   MATLYLDRKGLDLDVENGSLILREEGERIRSIPLTFLDRVVIRANISLSSAVLGELSESG 60

Query: 73  T-LLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPAR 131
           T  +V  G  G +V          +   L Q  L  D  LR +   ++   +    A + 
Sbjct: 61  TETVVLSGRQGRKVARIEGSRHNDARIRLRQYALFHDTTLRKRWAGRLVRSKIRSQARSL 120

Query: 132 RSV-----------------------------------EQLRGIEGSRVRATYALLAKQY 156
            ++                                    +L G+EG      +   +K +
Sbjct: 121 GTILKVRPDLTSSLLRPMEQLQSIGEKIRERTLDPFEISELLGLEGGAGSLYFESFSKAF 180

Query: 157 G--VTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KP 212
              + +  R   P      D  N  +S A + L+          G  P IGF H      
Sbjct: 181 PPSLGFTSRNRRPPR----DPANAVLSLAYTLLHFDGVRTANMVGLDPLIGFYHEPAYGR 236

Query: 213 LSFVY 217
            S V+
Sbjct: 237 DSLVF 241


>UniRef50_C0WE67 Crispr-associated protein n=1 Tax=Acidaminococcus sp. D21
           RepID=C0WE67_9FIRM
          Length = 290

 Score =  123 bits (308), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 35/281 (12%), Positives = 87/281 (30%), Gaps = 41/281 (14%)

Query: 14  RVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLE-PGTRVSHAAVRLAAQVG 72
             +++  Q  ++D       +      +  I +  +  +++E  G  ++   +       
Sbjct: 3   YRTIVITQRCKLDFCMNYVEVQTAVSKK-RIFIDEIKTLIIENTGVAITAYLLSELMNRK 61

Query: 73  TLLVWVGEAGVRVYASGQPGGA-RSDKLLYQAKLALDEDL-----RLKVVRKMFELRFGE 126
             L++  +A     +         S + + Q  +   E        +   +   +  F +
Sbjct: 62  VNLIFCDKAHNPQSSLLPLHARFDSIRKIKQQMIWSQEIKDEVWDCIVKAKIRQQALFLD 121

Query: 127 PAPARRSVEQLRGI------------EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGD 174
               +   + L               EG   +  +  L   +G ++          +   
Sbjct: 122 ELEKKEQSKMLMSYLDDVVSADAHNREGHAAKVYFNAL---FGNSFT--------RDLDS 170

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKA 232
            IN  ++   S L  +    I++AGY   +G  H     P +F  D+ +  +   V    
Sbjct: 171 PINAGLNYGYSLLLSLFNREIVSAGYLTQLGIFHENTYNPYNFSCDLMEPFR-ILVDRYV 229

Query: 233 FEIARRNPGEPDREVRLACRDIFRS----SKTLAKLIPLIE 269
           +     NP    ++ +    ++F+       +   L   I 
Sbjct: 230 Y---NMNPTTFAKDEKREIINLFQEILYIDDSRQFLANAIN 267


>UniRef50_C7G696 CRISPR-associated protein Cas1 n=2 Tax=Roseburia RepID=C7G696_9FIRM
          Length = 301

 Score =  122 bits (306), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 40/270 (14%), Positives = 84/270 (31%), Gaps = 37/270 (13%)

Query: 21  QYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TRVSHAAVRLAAQVGTLLVWVG 79
            + ++ + +    +     I   IP+  + CI++E     VS   ++  A +G  +    
Sbjct: 10  SHVKLSIKNQQLNIETD--IARQIPLEDINCIIIENQTVTVSAYLLQKMADMGIAVYVCD 67

Query: 80  EAGVRVYASGQP--GGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSV--- 134
           E  +                 L YQ +       RL     + ++R      A   +   
Sbjct: 68  EKHLPNAVLLPMVRHSRHFKILKYQIEAGKPLQKRLWQQIVVQKIRNQALCLAYLELDGS 127

Query: 135 EQLRGI------------EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISA 182
           E+L  +            E       +  L   YG+ ++              IN  ++ 
Sbjct: 128 EELMKMCKEVQSGDRTHVEAKAAAFYFKSL---YGLGFS--------RGNDHIINAALNY 176

Query: 183 ATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEI-ARRN 239
             + + G+   +I+  G  P+IG  H  +  +F    D+ +  +    +  A        
Sbjct: 177 GYAIVRGLIARSIVCYGLEPSIGVFHHSELNNFNLADDMIEPFRPLVDLYVAQNYDIAEI 236

Query: 240 PGEPDREVRLACRDIFRSS---KTLAKLIP 266
             +   E +     I       K   ++I 
Sbjct: 237 DSDLTPERKRGIFGIINYDMDMKGEKRIIS 266


>UniRef50_A9GQD8 Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So
           ce 56' RepID=A9GQD8_SORC5
          Length = 310

 Score =  121 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 36/230 (15%), Positives = 60/230 (26%), Gaps = 40/230 (17%)

Query: 85  VYASGQPGGARSDKLLYQAKLALDEDLRLKVVR-----KMFELR---------------- 123
           +  +        +  + Q + A DE   L   R     K+   R                
Sbjct: 50  LGRATGLESRNVELRVAQHRAASDEAFCLSFARGVVVSKIKNARTMLRRNHAAPEVAVLS 109

Query: 124 ----FGEPAPARRSVEQLRGIEGSRVRATYALLAKQYG--------VTWNGRRYDPKDWE 171
                   A    S+  L GIEG+  R  +   A                GR   P    
Sbjct: 110 ELDQLARKAAEAPSLPSLLGIEGTAARVYFGAFAGMLKGAGEARGEFDLEGRNRRPPR-- 167

Query: 172 KGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK--PLSFVYDIADIIKFDTVV 229
             D +N  +S A + L       +   G  P +GF H  +    +   D+ +  +     
Sbjct: 168 --DPVNALLSLAYALLAKDLATTLGTVGLDPLLGFYHQPRFGRPALALDLIEEFRPIVAD 225

Query: 230 PKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQP 279
                        PD + +     +        K +   E  +      P
Sbjct: 226 SVVVAAINNGVVAPD-DFQRFGGAVALRPAGRKKFLQAYERRMDQLVTHP 274


>UniRef50_B3W9S5 CRISPR-associated protein n=4 Tax=Lactobacillus RepID=B3W9S5_LACCB
          Length = 301

 Score =  120 bits (300), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 32/262 (12%), Positives = 83/262 (31%), Gaps = 35/262 (13%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTL 74
           S+I  Q+ ++   +   V+    G   ++P+  +  ++       +S  A+   A+    
Sbjct: 5   SLIVTQHCKVTTKNRTLVVQT-DGEVNNVPIEDINQVVFTTTRALLSADAITTLAEANAK 63

Query: 75  LVWVGEAGVRVYASGQPGG--ARSDKLLYQA----KLALDEDLRLKVVRKMFELRFGE-- 126
           +++ G  G  V  +        ++D +  Q      L  +   ++   +   + +  +  
Sbjct: 64  VIFSGRDGQPVTETTNLYSDRRKADLVRLQVNWPKSLVENLWTKIVAAKVSNQAQVTKLC 123

Query: 127 --------PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQ 178
                          +      E +  R  + L+   +G  ++               N 
Sbjct: 124 GFDNQSLLDDLDTLEINDRSNREATAARKYFKLI---FGDDFS--------RSDICATNA 172

Query: 179 CISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIA 236
            ++   S L   T  AI++AG+   IG  H+      +   D+ +  +       A    
Sbjct: 173 ALNYGYSILLSTTNRAIVSAGHITEIGMHHSSVANQYNLGSDLMEPFRPAIDYWVA---- 228

Query: 237 RRNPGEPDREVRLACRDIFRSS 258
            +   +    ++     +    
Sbjct: 229 NQKFTDLTPNIKYGLIALLNLE 250


>UniRef50_B3E1C9 CRISPR-associated protein Cas1 n=1 Tax=Methylacidiphilum infernorum
           V4 RepID=B3E1C9_METI4
          Length = 217

 Score =  118 bits (295), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 30/171 (17%), Positives = 58/171 (33%), Gaps = 11/171 (6%)

Query: 100 LYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVT 159
           + Q     D  L ++  R    L         R +  +RG EG   R  +   A+Q    
Sbjct: 1   MRQRYRPDDHKLLVRFKRACVGL------VHARQLPAVRGWEGWASRHYWRWFAQQVN-Q 53

Query: 160 WNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFVY 217
             G        +  D +N  ++   + L      A+  AG  P +G +H   G+  + V 
Sbjct: 54  LGGFEERRTHGQTQDPVNLALNYGYALLRHRLGVAVRLAGLDPYLGVLHEANGRHEALVS 113

Query: 218 DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
           D+ +I + + V      +      +P   V      ++   +   + +   
Sbjct: 114 DLVEIFRPE-VDRLVIRLIHLKMIQPKDFVFQDGL-LWLRPEARRRFVQSF 162


>UniRef50_Q03JI7 CRISPR-associated protein, Cas1 family n=40 Tax=Bacilli
           RepID=Q03JI7_STRTD
          Length = 289

 Score =  116 bits (292), Expect = 7e-25,   Method: Composition-based stats.
 Identities = 31/289 (10%), Positives = 86/289 (29%), Gaps = 40/289 (13%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLVWVGE 80
           + ++   +   +  +       I +  +  ++LE     ++   V+       L+++  +
Sbjct: 12  HSKLSYKNNHLIFRNSYKTEM-IHLSEIDILLLETTDIVLTTMLVKRLVDENILVIFCDD 70

Query: 81  AGVRV-YASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA---------PA 130
             +   + +       S   + +     +     +V   +   +    +           
Sbjct: 71  KRLPTAFLTPYYARHDSSLQIARQIAWKENVKC-EVWTAIIAQKILNQSYYLGECSFFEK 129

Query: 131 RRSVEQL---------RGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCIS 181
            +S+ +L            EG   R  +  L   +G  +          E  + IN  + 
Sbjct: 130 SQSIMELYHGLERFDPSNREGHSARIYFNTL---FGNDFT--------RESDNDINAALD 178

Query: 182 AATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRN 239
              + L  +    ++  G    IG  H       +   DI +  +   +    ++    N
Sbjct: 179 YGYTLLLSMFAREVVVCGCMTQIGLKHANQFNQFNLASDIMEPFRP-IIDRIVYQNRHNN 237

Query: 240 PGEPDREVRLACRDIFR---SSKTLAKLIPLI-EDVLAAGEIQPPAPPE 284
             +  +E+     + +        L+ ++    + V+ A        PE
Sbjct: 238 FVKIKKELFSIFSETYLYNGKEMYLSNIVSDYTKKVIKALNQLGEEIPE 286


>UniRef50_C7XMU1 CRISPR-associated protein cas1 n=2 Tax=Fusobacterium
           RepID=C7XMU1_9FUSO
          Length = 292

 Score =  116 bits (291), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 35/255 (13%), Positives = 88/255 (34%), Gaps = 36/255 (14%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGT-RVSHAAVRLAAQVGTLLVWVGE 80
             ++D+   +  +    G    I +G V  ++LE  T  ++ A +    +    +++  E
Sbjct: 12  RSKLDLRYNSISIRRDNGTDF-IHIGEVNTLILETTTISITAALMCELIKQKVKVIFCDE 70

Query: 81  AGVRVY-ASGQPGGARSDKLLYQAKLALDE--------------DLRLKVVRKMFELRFG 125
                +      G       + +     D               + ++K+++K+ +  + 
Sbjct: 71  KSNPHFELLPFYGSHDCSAKIKEQIAWTDFLKESLWTIIVTEKIENQMKLLKKLNKEEYK 130

Query: 126 EPAPARRSVE--QLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAA 183
                   +E       EG   +  ++ L   +G  ++          K +++N  ++  
Sbjct: 131 ILQEYASQIEHNDNTNREGHSAKIYFSAL---FGNNFS--------RNKENSLNAFLNYG 179

Query: 184 TSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPG 241
              L       I+A GY   IG  H       +   D+ +  +   V   A+   + NP 
Sbjct: 180 YQLLLSTFNKEIVANGYLTQIGIFHKNMFNYYNLSSDLMEPFR-VIVDELAY---KENPQ 235

Query: 242 EPDREVRLACRDIFR 256
           + +++ +   ++I  
Sbjct: 236 KFEKDEKRKLQNILN 250


>UniRef50_C2EF73 CRISPR-associated Cas1 family protein n=1 Tax=Lactobacillus
           salivarius ATCC 11741 RepID=C2EF73_9LACO
          Length = 308

 Score =  116 bits (290), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 36/295 (12%), Positives = 94/295 (31%), Gaps = 43/295 (14%)

Query: 9   IPLKDRVSMIFLQYGQ-IDVIDGAFVLIDK-TGIRTHIPVGSVACIMLEPGTR-VSHAAV 65
           I ++D   +I+++    + +   +F L +       + P   V  ++ +  +  +S   +
Sbjct: 5   IVMRD---IIYIENKHFVGITKDSFKLKNVVDESERYFPFDEVDYLIFDSRSSFISERVI 61

Query: 66  RLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFG 125
               +    L++  +            G          +LA+ +  + ++ +K+ + +  
Sbjct: 62  TTCVENNIGLIFCDKTHTPQLLMTSIYGQNERFKRQSKQLAMSKKTKGRIWQKIIKTKIN 121

Query: 126 EP-------APARRSVEQLRGI------------EGSRVRATYALLAKQYGVTWNGRRYD 166
                        +  + +R I            E    R  ++ L          + + 
Sbjct: 122 NQADCLKYVVKNDKVSDIVRSIGKTVTEGDKNNHEAYAARVYFSNL--------FSKSFK 173

Query: 167 PKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIK 224
              ++  D IN  ++   + L       ++  G  P+ G  H      F    DI ++ +
Sbjct: 174 RGRYD--DIINSSLNYGYAILRSAIRKELVIYGLEPSWGIHHVSTENPFNLSDDIIEVYR 231

Query: 225 FDTVVPKAFEIARRNPG-EPDREVRLACRDIFRSSKTLA----KLIPLIEDVLAA 274
                    E+   N   E D E++     +      +      L+  I+  + +
Sbjct: 232 PFL-DALVVELLNNNESEELDIELKKEIIKVLFEKCIIDNKVYNLLDAIKITIKS 285


>UniRef50_C8PNV3 CRISPR-associated protein Cas1 n=1 Tax=Treponema vincentii ATCC
           35580 RepID=C8PNV3_9SPIO
          Length = 296

 Score =  115 bits (289), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 32/282 (11%), Positives = 89/282 (31%), Gaps = 38/282 (13%)

Query: 17  MIFLQYGQ-IDVIDGAFVLIDKT-GIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGT 73
            +F  +   + V     V+  +     T +P+  +  +++E     ++   +    +   
Sbjct: 5   TLFFSHAVCLSVKHKQLVIFSEETQEETLVPIEDIGFVIVENERVSLTIPLINELTENNC 64

Query: 74  LLVWVGEAGVRVYASGQPGGARSDKLLYQ---AKLALDEDLRLKVVRKM--FELRFGEPA 128
            L++  E  +             +++  Q   A++     ++ K  +++  ++++     
Sbjct: 65  ALIFCNEKHMPF---SMTMPLDCNEIQSQLFSAQINAKLPVKKKCWKQVVEYKIKNQGLL 121

Query: 129 PARRSVEQLR--------------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGD 174
             +  ++  R               +E    +  +  L   +G  W            G+
Sbjct: 122 LKKYDLDFARLADFSKRVKSGDSTNMESQAAKFYWDNL---FGKNW-------CRNRFGE 171

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS--FVYDIADIIKFDTVVPKA 232
             N  ++   + L   T  A+  +G  PA+G  H  K  +     D+ +  +        
Sbjct: 172 FPNNYLNYGYAILRAATARALAGSGLLPALGIHHHNKYNAYCLADDLMEPYRPFIDDEVI 231

Query: 233 -FEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLA 273
            +     +  E   E +     +      +  L   +   L+
Sbjct: 232 EYISTNPDEKELGLEFKKKILKVLTRDVKMNNLTRPMMAALS 273


>UniRef50_UPI00016B206F hypothetical protein cdiviTM7_00753 n=1 Tax=candidate division TM7
           single-cell isolate TM7c RepID=UPI00016B206F
          Length = 296

 Score =  115 bits (287), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 34/263 (12%), Positives = 79/263 (30%), Gaps = 37/263 (14%)

Query: 22  YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLVWVGE 80
             ++ + D   V+  +T     +P+  +  ++L+  G   +   +   A  GT  +   E
Sbjct: 11  PARLSLRDNQLVIAQETE--ATLPIEDIDSLILDGYGITTTTNLLAALATKGTTTIICDE 68

Query: 81  AGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP----ARRSVEQ 136
             +                + + ++A+ + L+ ++ +++   +    A            
Sbjct: 69  KHLPASVLLPYSQHSRQAKVSRQQIAMSQPLKKQLWQQIIISKITNQADVLRSTGLDDAA 128

Query: 137 LR------------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAAT 184
           LR              E    R  +  L                 W      N  ++   
Sbjct: 129 LRTHISDVKSGDTSNRESIAARIYFDQLLDDA-------TRRKPIWH-----NTALNYGY 176

Query: 185 SCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGE 242
           + +       I A G   + G  H  +  SF    D+ +  +    +    ++A  + G+
Sbjct: 177 AMVRSHIARHIAARGLVASQGIFHHNELNSFNLADDLIEPYRAAVDLYVLEKVAPLHVGD 236

Query: 243 PD----REVRLACRDIFRSSKTL 261
            D    +  R    DI      +
Sbjct: 237 RDASLTKHDRQLIIDILNYYVIM 259


>UniRef50_A8REI1 Putative uncharacterized protein n=2 Tax=unclassified
           Erysipelotrichaceae RepID=A8REI1_9FIRM
          Length = 300

 Score =  114 bits (285), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 35/308 (11%), Positives = 94/308 (30%), Gaps = 56/308 (18%)

Query: 17  MIFLQ---YGQIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTRVSHAAVRLAAQVG 72
           +++++   + Q+ + +    +    G     P+  +  +++    + ++   V    +  
Sbjct: 5   VLYIENQYHLQLYLDN--LKVETSQG-DIQFPISDIQILVIDHYRSTLTVPLVNKLTENN 61

Query: 73  TLLVWVGEAGVRV-YASGQPGG-ARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP- 129
             ++  G   +   Y     G  A+S  ++ Q     +E  ++ + +++ + +       
Sbjct: 62  VCVIICGIDHLPKSYILPMNGHFAQSGNIMKQIT-WSNEIKQI-LHQQIVKAKIFNQIEI 119

Query: 130 ------------------ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWE 171
                                 +      EG   +  +  +     + +           
Sbjct: 120 LKTNQCKYEVIKKLYEFYDTVDLGDATNREGLAAKMYFREMFGNDFIRFE---------- 169

Query: 172 KGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVV 229
             D IN  ++   S    +  + I+  GY P +G  H GK   F    DI ++ +   V 
Sbjct: 170 -DDVINAGLNYGYSIFRSLISSIIVGKGYLPNLGIFHKGKTNMFNLSDDIIEVFRP-IVD 227

Query: 230 PKAFEIARRNPGEPDREVRLACRDIFRSS-----------KTLAKLIPLIEDVLAAGEIQ 278
              ++  +       +  R     +                 + + +  I  V+  G+I 
Sbjct: 228 KYVYDNLKEELLFKSKH-REELIQLTVKKIEIDGKLQTVPNAVNEYVESILKVIETGKIT 286

Query: 279 PPAPPEDA 286
               P   
Sbjct: 287 DFKFPSPH 294


>UniRef50_A8ABE8 CRISPR-associated protein Cas1 n=1 Tax=Ignicoccus hospitalis KIN4/I
           RepID=A8ABE8_IGNH4
          Length = 310

 Score =  114 bits (285), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 36/260 (13%), Positives = 80/260 (30%), Gaps = 43/260 (16%)

Query: 22  YGQIDVIDGAFVLI---DKTGIRTHIPVGSVAC-IMLEPGTRVSHAAVRLAAQVGTLLVW 77
           +  +        +    D   +    P   +   + +  G  VS AA++L  +     ++
Sbjct: 8   HAFVGRKGYMITVRYKKDGKEVTEAFPALDIEMAVFVGKGITVSTAALQLLEEQNVPTLF 67

Query: 78  VGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGE----------- 126
            G                S     Q  +  + +L +KV ++    +              
Sbjct: 68  HGVD-WSFVTINPVKVGWSRARKNQYSM-GETELGVKVAKEFIFGKLEGMSNVAKNLSYK 125

Query: 127 -----------------PAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKD 169
                               + ++++ ++ +E       +  + +        R   P+ 
Sbjct: 126 GKKPTPNSDYWRSEGRGELASCKNLDCVKKLEAEWSSKLWKDIVQFVP---GMRSRVPR- 181

Query: 170 WEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL--SFVYDIADIIKFDT 227
               D  N+ +    + LY V   A++ AG  P  G +H  +    SFVYD +++ K   
Sbjct: 182 --GNDPPNRTLDYLYALLYSVCNHALVGAGLDPYAGLIHRERAGKLSFVYDFSEMFKP-M 238

Query: 228 VVPKAFEIARRNPGEPDREV 247
            +       R    E + + 
Sbjct: 239 AIYVMATAIRTYKIELEGDF 258


>UniRef50_A7HP88 CRISPR-associated protein Cas1 n=1 Tax=Parvibaculum lavamentivorans
           DS-1 RepID=A7HP88_PARL1
          Length = 311

 Score =  114 bits (285), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 32/251 (12%), Positives = 81/251 (32%), Gaps = 16/251 (6%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLVWVGEAG 82
           ++ V +   V+      +  +P+  +  ++++      + A      + G  ++  G   
Sbjct: 14  RLSVANKQLVIERPDLPKATLPIEDLGVVIVDDLRATYTQAVFIELLEAGATVMVTGRDH 73

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA--------PARRSV 134
           +                 ++A++   E  + +  + +   +  +               +
Sbjct: 74  LPAGMMLPLDAHHIQTERHRAQVEASEPTKKRAWQALIRSKIAQQGIVLAHFTGEHGGLL 133

Query: 135 EQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAA 194
              R +         A  A++Y     G+ +      +G  +N  ++   + +   T  A
Sbjct: 134 PMARRVRSGDPDNLEAQAAQRYWPRLFGKDFRRDRDLEG--VNALLNYGYAVVRAATARA 191

Query: 195 ILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEP---DREVRL 249
            +AAG  P++G  H  +   F    D+ +  +            +     P   DR+ R 
Sbjct: 192 TVAAGLIPSLGVFHRNRANPFCLADDLLEPYRPYVDWRVRLLANQMGEEAPSLDDRDTRA 251

Query: 250 ACRDIFRSSKT 260
           A   IF  +  
Sbjct: 252 ALLSIFNETVL 262


>UniRef50_Q5LZX6 Putative uncharacterized protein n=2 Tax=Streptococcus thermophilus
           RepID=Q5LZX6_STRT1
          Length = 207

 Score =  113 bits (283), Expect = 8e-24,   Method: Composition-based stats.
 Identities = 33/210 (15%), Positives = 69/210 (32%), Gaps = 36/210 (17%)

Query: 15  VSMIFLQYG--QIDVIDGAFVLI-DKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQV 71
           +S ++ Q     + + +   ++  D   I   + +  V  ++L    +++   ++  ++ 
Sbjct: 1   MSDLYSQRSNYYLSLSEQRIIIKNDNKEIVKEVSISLVDNVLLFGNAQLTTQLIKALSKN 60

Query: 72  GTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE---------- 121
              + +    G  + +          K   QAK   +ED RL+V R +            
Sbjct: 61  KVNVYYFSNVGQFISSIETHRQDEFQKQELQAKAYFEEDFRLEVARSIATTKVRHPIALL 120

Query: 122 --------------LRFGE---PAPARRSVEQLRGIEGSRVRATYALLAKQYG--VTWNG 162
                          RF +         S+ ++ G EG   ++ +  L         +NG
Sbjct: 121 REFDTDGLLDTSDYSRFEDSVNDIQKAYSITEIMGYEGRLAKSYFYYLNLLVPNDFHFNG 180

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTE 192
           R   P      D  N  ++   S LY    
Sbjct: 181 RSRRP----GEDCFNSALNFGYSILYSCLM 206


>UniRef50_B5ZLL1 CRISPR-associated protein Cas1 n=2 Tax=Gluconacetobacter
           diazotrophicus PAl 5 RepID=B5ZLL1_GLUDA
          Length = 297

 Score =  113 bits (283), Expect = 8e-24,   Method: Composition-based stats.
 Identities = 38/284 (13%), Positives = 93/284 (32%), Gaps = 45/284 (15%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPG-TR 59
           M W  ++                ++   +   V+  + G    + V  +AC++L+     
Sbjct: 1   MAWRGVHIS-----------HPSRLTHRNRQLVVA-QDGGEVSLAVEDIACLILDTRQVS 48

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM 119
           ++ + +   A+ G  ++                   +   +  A++++ + L+ ++ + +
Sbjct: 49  ITGSLLSALAENGVAMIVPDARHHPAGILLPFHQHHAQAHIAHAQISISQPLKKRLWQTL 108

Query: 120 FELRFGEP--------APARRSVEQLRG---------IEGSRVRATYALLAKQYGVTWNG 162
              +             P  +++  + G         +E    RA +A L   +      
Sbjct: 109 VVAKIRNQAALLDQLGRPQGQTIAAMAGRVASGDPGNVEAQAARAYWASLFSDF------ 162

Query: 163 RRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIA 220
                    + D  N  ++   + +      A +A G  PA G  H  K  +F    D+ 
Sbjct: 163 -----TRANENDRRNALLNYGYAIMRAAIARACVALGLLPAFGVHHASKTNAFNLVDDLI 217

Query: 221 DIIKFDTVVPKAFEIARRNPGE-PDREVRLACRDIFRSSKTLAK 263
           +  +   V   A + A  + G+    E R     I   +  + +
Sbjct: 218 EPFRP-FVDRMAHDRALEHVGDTLSIEDRRQMSTILNDNAAIGR 260


>UniRef50_Q6KIQ8 Conserved expressed putative DNA-repair protein n=1 Tax=Mycoplasma
           mobile RepID=Q6KIQ8_MYCMO
          Length = 300

 Score =  113 bits (282), Expect = 9e-24,   Method: Composition-based stats.
 Identities = 31/284 (10%), Positives = 82/284 (28%), Gaps = 50/284 (17%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTR 59
           M W  +      D    ++L    I   +   +L           +  +  I+     + 
Sbjct: 1   MGWKIVEI--NTDEYVHLYLNNLYIKRKNEKILLN----------IRDIDTILFNNQYST 48

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRV-YASGQPGGARSDKLLYQAKLALDEDLRLKVVRK 118
           +S   +   A+    ++++ E      Y     G   S K++ +      E   + + + 
Sbjct: 49  ISIRLLTFLAKNNVNIIFMNEKNEPNSYLIPIEGNHNSLKVVAEQVKWTKEYKAI-LWKD 107

Query: 119 MFELRFG----------------------EPAPARRSVEQLRGIEGSRVRATYALLAKQY 156
           + + +                        +      ++  +   EG   +  + +    Y
Sbjct: 108 IIKNKIHNQKNLLIKNKLFNNSEFGIEYFDDLINNVNLFDISNREGHAAKVYWNM---TY 164

Query: 157 GVTW-NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPL-- 213
              +          ++K + +N  ++   S L      +I+  G  P     H       
Sbjct: 165 SKEFIRNNSATKLKFDKFEIVNAILNYGYSILRSSAIQSIIKKGLDPRFSIFHKSFSNFF 224

Query: 214 SFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRS 257
           +   D+ +I +   V   A+        + +    +  +D   +
Sbjct: 225 ALASDLIEIFRP-LVDEIAY------LHKDETFFDVKIKDELIN 261


>UniRef50_B1BJM4 Crispr-associated protein Cas1 n=2 Tax=Clostridium perfringens
           RepID=B1BJM4_CLOPE
          Length = 299

 Score =  113 bits (282), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 25/245 (10%), Positives = 76/245 (31%), Gaps = 35/245 (14%)

Query: 39  GIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSD 97
           G    +P+  ++ +++E     ++   +   ++     +   E  + V  +         
Sbjct: 26  GEEFLVPIEDISVLLIEGVAVNLTARLLSKLSENNVATIICDEKHLPVSINIPINTHYKT 85

Query: 98  KLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIE--------------GS 143
             + + + +       ++ + + + +          + ++ G E              G+
Sbjct: 86  YKVLKQQFSQSAAFSKRIWQSIIKQKLINQG-KCLDILEISGYEFLKKLSDAVESGDKGN 144

Query: 144 R----VRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAG 199
           R     +  +  L         G+ +   D    + IN  ++   + L      +++  G
Sbjct: 145 REAIGAKYYFKNL--------FGKAFVRDD---ENGINSALNYGYTILRSAIARSLVMYG 193

Query: 200 YAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRS 257
           +   +G  H  +  SF    D  +  +    +  A  +         +E R+   D+   
Sbjct: 194 FNTTLGVNHCNELNSFNLADDFIEPFRPIVDLWVAQNM--DYDDILTKEDRIGLVDLLNY 251

Query: 258 SKTLA 262
              + 
Sbjct: 252 QCVID 256


>UniRef50_Q5HK87 CRISPR-associated protein Cas1 n=1 Tax=Staphylococcus epidermidis
           RP62A RepID=Q5HK87_STAEQ
          Length = 301

 Score =  112 bits (280), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 35/287 (12%), Positives = 94/287 (32%), Gaps = 41/287 (14%)

Query: 17  MIFLQ-YGQIDVIDGAFVLID--KTGIRTHIPVGSVACIMLEPGTR-VSHAAVRLAAQVG 72
           +I+++ +  +   + +    +      + ++    +  I+ +      SH  V    +  
Sbjct: 4   VIYVENHYFVTAKENSIKFRNVIDKSEKFYL-FEEIEAIIFDHYKSYFSHKLVIKCIEND 62

Query: 73  TLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP----- 127
             +++  +    V       G  +     Q++  L    + ++ +K+   +         
Sbjct: 63  IAIIFCDKKHSPVTQLISSYGMVNRLKRIQSQFQLSGRTKDRIWKKIVINKIFNQTRCLE 122

Query: 128 -APARRSVEQLRGI------------EGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGD 174
                 +V+ + G             E    R  +  L         G+++    +   D
Sbjct: 123 NNLHNENVKLMLGFAKEVSSGDKSNKEAHATRIYFKDL--------FGKQFKRGRYN--D 172

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKA 232
            IN  ++   S L       +   G+  ++G  H  K   F    DI ++ +   V    
Sbjct: 173 VINSGLNYGYSILRSFINKELAIHGFEMSLGIKHQSKENPFNLADDIIEVFRP-FVDNIV 231

Query: 233 FEIA-RRNPGEPDREVRLACRDIFRSSKTLA----KLIPLIEDVLAA 274
           +EI  ++N    D   +    ++      +     +L+  ++ V+ +
Sbjct: 232 YEIVFKKNIDTFDINEKKLLLNVLYERCIIDKKVVRLLDSVKIVIQS 278


>UniRef50_D1AUW5 CRISPR-associated protein Cas1 n=1 Tax=Streptobacillus moniliformis
           DSM 12112 RepID=D1AUW5_STRM9
          Length = 308

 Score =  111 bits (278), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 38/295 (12%), Positives = 86/295 (29%), Gaps = 47/295 (15%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLL 75
           ++  Q   I   +   ++      +  +P+  ++ I+ E   + +S   +   +     +
Sbjct: 6   VLITQKSYIHFENDNLIVEKDD-KKLSVPISDISIIVFESLESYISLRIISELSLRNITM 64

Query: 76  VWVGEAGVRV-YASGQPGGAR---SDKLLYQAKLALDE--DLRLKVVRKMFELRFGEPAP 129
           ++     + V Y+       R      L  Q      E    +L   +     +  E   
Sbjct: 65  IFCDYRHMPVAYSLPINQHYRIPYVHSLQGQQTSKSKEFVWEKLLKAKIRNSKKVLELEN 124

Query: 130 ARRSVEQLR-------------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
           A   + +L                EG+  +  +  L   YG  +           + D+I
Sbjct: 125 ASSDLIELMQKYEDEVIGSDVQNREGTAAKVFFNYL---YGTNF-------CRQNERDSI 174

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFE 234
           N  +              +   G+A  IG  H+      +  YD  +  +   +    F 
Sbjct: 175 NMALDYGYGVFRSAITRLLCTYGFATYIGVHHSSMMNAFNLTYDFIEPYRP-IIDYYVFN 233

Query: 235 IARRNPGEPD--REVRLACRDIFRSSK-----------TLAKLIPLIEDVLAAGE 276
              R   + +   + R     +  ++            ++  LI    + L  G 
Sbjct: 234 HLYRFEKDDELKTDTRKELISLLNANIKVNEKEYTVLYSMELLIKSYLNFLEEGN 288


>UniRef50_C2CKI7 CRISPR associated protein n=1 Tax=Anaerococcus tetradius ATCC 35098
           RepID=C2CKI7_9FIRM
          Length = 292

 Score =  110 bits (275), Expect = 6e-23,   Method: Composition-based stats.
 Identities = 32/257 (12%), Positives = 80/257 (31%), Gaps = 47/257 (18%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTR 59
           MTW            +++  +  ++ +  G  ++ D     + I +  ++ I++      
Sbjct: 1   MTWR-----------TVVISKRSKLFLKMGHMIVRDFENNISRIYLKDISHIIVTTTEAS 49

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVY--ASGQPGGARSDKLLYQAKLALDEDLRLKVVR 117
           ++ A +    +    L+   E G      +S       S+K+  Q +   D     +V +
Sbjct: 50  ITLALINEIQKQKIKLIICDEKGNPSAELSSYYNSYNSSEKIRAQIRWTSDIKG--EVWK 107

Query: 118 KMFELRFGEP--------APARRSVEQLRG---------IEGSRVRATYALLAKQYGVTW 160
           ++ E +                  +E   G          E    +  +  L        
Sbjct: 108 RIVEEKIKNQMHLLKSFRLEKSNLLEGYLGQVEIFDSTNREAHAAKVYFNSL-------- 159

Query: 161 NGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYD 218
            G  +   D      +N  ++   S +       +++ GY   +G  H       +   D
Sbjct: 160 FGNDFSRNDDTN---LNANLNYGYSIILSAINRCVVSMGYLTQLGIFHENIYNQFNLSSD 216

Query: 219 IADIIKFDTVVPKAFEI 235
           + +  +   V  +  ++
Sbjct: 217 LIEPWRP-MVDREVLDM 232


>UniRef50_Q5HSQ9 CRISPR-associated protein Cas1 n=12 Tax=Campylobacterales
           RepID=Q5HSQ9_CAMJR
          Length = 296

 Score =  109 bits (272), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 30/264 (11%), Positives = 85/264 (32%), Gaps = 35/264 (13%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTL 74
           +++     ++++     V+  +      + +  +  I+LE     +S A     A+   +
Sbjct: 9   TLLISSNAKLNLELNHLVI-KQDENIAKLFLKDINIIVLESLQVSISSALFNAFARHKII 67

Query: 75  LVWVGEAG--VRVYASGQPGGARSDKLLYQAKLALDEDLRLK-------------VVRKM 119
           L+   E      V+         +     Q  ++  +   L              +++K 
Sbjct: 68  LLTCDETHSINGVFTPFLGHFQSAKIAKEQMNVSAQKKAILWQKIIKNKILNQAFILKKY 127

Query: 120 FELRFGEPAPA---RRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
            ++           + S+   + IE       +  L   +G +++         ++    
Sbjct: 128 NKIEQSNELINLAKKVSLNDSKNIEAVAAALYFKTL---FGTSFS--------RDELCFE 176

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFE 234
           N  ++   + +      A+  +G  P +G  H     SF    D+ ++ +   V     +
Sbjct: 177 NSALNYGYAIIRACIIRAVCISGLLPWLGIKHDNIYNSFALCDDLIEVFRAS-VDDCVLK 235

Query: 235 IARRNPGEPDREVRLACRDIFRSS 258
           +   +     ++ + A     +S 
Sbjct: 236 LKGESEF-LSKDDKRALIGNLQSK 258


>UniRef50_D2PIT7 CRISPR-associated protein Cas1 n=2 Tax=Sulfolobus
           RepID=D2PIT7_SULIS
          Length = 255

 Score =  105 bits (262), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 43/241 (17%), Positives = 79/241 (32%), Gaps = 39/241 (16%)

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKM 119
           +S   +   +     +   G+    V  S        D    Q    + ED ++ + ++ 
Sbjct: 1   MSSEVLLFLSSQNVPVAIHGKYSDVVLVSPFMNSMS-DVRSKQY--CMSEDRKIILAKRF 57

Query: 120 FELRFGEPAPARR---------------------SVEQLRGIEGSRVRATYALLAKQYGV 158
            E +        +                      +  LR IE    R  +  L K    
Sbjct: 58  IEGKVRGMFNVAKYFGYLNQIEVKVEELDLRGVNDLNSLRLIEAEYGRKAWDELKKFLPR 117

Query: 159 TWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHT--GKPLSFV 216
            + GR          D IN+ I  A S +Y +   A++A G  P  G +H+     LSF 
Sbjct: 118 EFTGR-----KPRNEDPINRAIDYAYSIIYSLCTHALIAVGLDPYAGVMHSNFPGRLSFT 172

Query: 217 YDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGE 276
           YD +++ K    V      +RR     D+         + S ++   +   +  +L   +
Sbjct: 173 YDFSEMFK-SVAVHVVISSSRRVKLSLDK-------KGYLSKESAEYITKYLYTILRKKK 224

Query: 277 I 277
           +
Sbjct: 225 V 225


>UniRef50_C4ZA17 Putative uncharacterized protein n=2 Tax=Eubacterium
           RepID=C4ZA17_EUBR3
          Length = 302

 Score =  105 bits (262), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 39/284 (13%), Positives = 86/284 (30%), Gaps = 39/284 (13%)

Query: 17  MIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTLL 75
           ++      I V     ++  K G    IP+  ++ I+L+   + +S   +   A+ G  L
Sbjct: 6   ILIENEVTIKVKLNNLII-TKCGEDIWIPLDDISMIVLDNLASNLSTRLMCQLAEQGIGL 64

Query: 76  VWVGEAGVR--VYASGQPGGARSDKLLYQA--------KLALD--EDLRLKVVRKMFELR 123
           +   +  +    Y++       S  + +Q         KL     +       +    + 
Sbjct: 65  MLYNQQHLPTGFYSAYDNHSRASKVIGFQIDKEQDYYGKLWQQIVKIKIENQAKAYQIMT 124

Query: 124 FGEPAPAR---RSVEQLRG----IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTI 176
                P +    S   L G     E    +  + LL         G  +   + +    +
Sbjct: 125 RDSDGPEKIIEFSKNILIGDKSNREAHAAKVYFNLL--------MGTSFSRGNEDI--LL 174

Query: 177 NQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFE 234
           N  +    + + G    A +  G    IG  H       + V D+ + ++    +     
Sbjct: 175 NSGLDYGYAVIRGYIARACVGYGLNTQIGIHHKSEYNRFNLVDDLMEPLRPIVDIVAYNS 234

Query: 235 IARRNPGEPDREVRLACRDIFRSS----KTLAKLIPLIEDVLAA 274
           +       P+   R     I        +    +  +IE+ +  
Sbjct: 235 MKNDKYFTPEH--RRKLVSILNMKIMYREKKMYMCNMIENYIEQ 276


>UniRef50_UPI0001977683 putative CRISPR-associated protein n=1 Tax=Helicobacter cinaedi
           CCUG 18818 RepID=UPI0001977683
          Length = 298

 Score =  104 bits (259), Expect = 5e-21,   Method: Composition-based stats.
 Identities = 32/270 (11%), Positives = 83/270 (30%), Gaps = 37/270 (13%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVA-CIMLEPGTRVSHAAVRLAAQVGTL 74
           S++     ++ +     VL         + +  +   I+  P   ++ A +   A+   +
Sbjct: 9   SVLVSSEAKLSLQANHLVLKQTN-KEAKLFLKDIHFVILESPQILITSALLSAFAKHNIV 67

Query: 75  LVWVGEAGVRVYA-SGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPA----- 128
           L+   E+           G  +  K+  +  +       + V +K+ + +    A     
Sbjct: 68  LLTCDESHHINGIMHSYLGHFQHAKIAKEQMMVSTHKKAI-VWQKIVKNKITNQAHILKL 126

Query: 129 --PARRSVEQL-----------RGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDT 175
              ++ S E L           R +E       +  L         G+ +     ++ + 
Sbjct: 127 HHKSKESDELLSFAKNVSLGDSRNLEAVAAAIYFKAL--------FGKEFHR---DEINF 175

Query: 176 INQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAF 233
           IN  ++   + L       +  +G    +G  H     SF    D+ ++ +   V     
Sbjct: 176 INSALNYGYAILRACIVRNVCISGLITWLGIKHDNMYNSFNLCDDLIEVFRPW-VDLCVL 234

Query: 234 EIAR-RNPGEPDREVRLACRDIFRSSKTLA 262
           ++             +    +I + +  + 
Sbjct: 235 KLNTLDKEATLRPNDKRELINILQQAALID 264


>UniRef50_A1RZT8 CRISPR-associated protein Cas1 n=1 Tax=Thermofilum pendens Hrk 5
           RepID=A1RZT8_THEPD
          Length = 327

 Score =  103 bits (258), Expect = 6e-21,   Method: Composition-based stats.
 Identities = 44/275 (16%), Positives = 89/275 (32%), Gaps = 36/275 (13%)

Query: 24  QIDVIDGAFVLIDKTGIRTHIPVGSVA-CIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAG 82
           ++ V   + V+I          +  V   +++  G ++S +   + A  G  L  + +  
Sbjct: 11  EVTVSSRSTVVIKSGNRVFERALRDVDAVLVVGSGIKISSSLPPVLALHGIPLSILAKGH 70

Query: 83  VRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEP--------------- 127
           V V      G   ++    Q  L  +    L +  +  + R                   
Sbjct: 71  VAV-LLNPVGTKYNNYRALQYTLPKN--KALAIALEYLKSRVRGMASIIRNRGGRLPALP 127

Query: 128 --------APARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDP-----KDWEKGD 174
                       R    +R  E +     +  + K    +      +      +     D
Sbjct: 128 EPPDPALYEDPARLESDIRSWEAAASNTLWDEVFKLLDPSAARELRERYGFAGRKPGHPD 187

Query: 175 TINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGK-PLSFVYDIADIIKFDTVVPKAF 233
            +N+ ISA  + LY ++  A++AAG  P  GF+H  +  +   +D A+  K    V  A 
Sbjct: 188 PLNKAISAMYAVLYTLSTKALVAAGLDPTYGFLHRTQYSVPLAFDYAEAFKP-LAVEAAL 246

Query: 234 EIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLI 268
           ++          E     +D     K + +L   +
Sbjct: 247 DLVNEEGLPTLSEDGDLDKDSLN--KAMKRLYRYL 279


>UniRef50_Q73QW5 CRISPR-associated protein Cas1 n=7 Tax=Bacteria RepID=Q73QW5_TREDE
          Length = 290

 Score =  102 bits (255), Expect = 1e-20,   Method: Composition-based stats.
 Identities = 41/290 (14%), Positives = 92/290 (31%), Gaps = 32/290 (11%)

Query: 16  SMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEP-GTRVSHAAVRLAAQVGTL 74
           +++     ++D+     V+         + +  ++ +++E     ++ A +    +    
Sbjct: 5   TVVISNRAKLDLHLNHLVVR--GEKTQKVFIEEISVLIIETTAVSITAALLNELIKQKVK 62

Query: 75  LVWVGEAGVRVY-ASGQPGGARSDKLLYQAKLALDEDLRL--------KVVRKMFELRFG 125
           +++  E         G  G   + + +           +L        K+ ++ + L   
Sbjct: 63  VIFCDEKRNPASELIGYYGSHDTSEKIRLQIKWDKNIKQLVWTEVVTEKIRQQKYLLEKL 122

Query: 126 EPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATS 185
               A    E +  I+ +      A  AK Y     G  +          IN  ++   S
Sbjct: 123 NLPQASLLAEYITDIDINDKTNKEAHAAKAYFAALFGAGFSRSLDI---PINAALNYGYS 179

Query: 186 CLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEP 243
            L       I+A GY   +G  H     P +   D+ +  +   V  + F++   NP + 
Sbjct: 180 ILLSAFNREIIANGYITQLGIFHDNMFNPFNLGSDLMEPFRP-LVDAEVFKL---NPQKF 235

Query: 244 DREVRLACRDIFRSS-----------KTLAKLIPLIEDVLAAGEIQPPAP 282
           + E +L    +               K +   +  I D L   +I     
Sbjct: 236 EHEEKLKIVSVINKKVLINNKEHYLNKAIEIFVHSIFDALNEKDISQINF 285


>UniRef50_A7BYT7 Putative uncharacterized protein n=1 Tax=Beggiatoa sp. PS
           RepID=A7BYT7_9GAMM
          Length = 165

 Score =  101 bits (251), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 17/133 (12%), Positives = 39/133 (29%), Gaps = 5/133 (3%)

Query: 138 RGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILA 197
            GIEGS  +  +A     +   W  +  +       D +N  +S + +            
Sbjct: 1   MGIEGSIAQQYFAKWRILWDDMWGFKERNR--RPPRDPVNALLSLSYTLAGNSIGQLAST 58

Query: 198 AGYAPAIGFVHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIF 255
            G   ++GF+H       S   D+ + ++        ++   +    P +      +   
Sbjct: 59  RGLDISLGFLHAPLNGRPSLALDLLEPVRPWI-DQWIWQQVDKGLLTPKQFSNNLEQGCR 117

Query: 256 RSSKTLAKLIPLI 268
              +         
Sbjct: 118 LDKEGRQAFFSAW 130


>UniRef50_C5NZ03 CRISPR-associated protein Cas1 n=2 Tax=Firmicutes
           RepID=C5NZ03_9BACL
          Length = 291

 Score =  100 bits (249), Expect = 8e-20,   Method: Composition-based stats.
 Identities = 28/256 (10%), Positives = 69/256 (26%), Gaps = 46/256 (17%)

Query: 1   MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIML-EPGTR 59
           MTW     I ++DR         ++D       +  +   R  + +  +  I++      
Sbjct: 1   MTW---RTIIVRDR--------AKLDYSLNFLTVRKEAETRK-VSLSEIYMIIIESTAVS 48

Query: 60  VSHAAVRLAAQVGTLLVWVGEAGVRVY-ASGQPGGARSDKLLYQAKLALDEDLRLKVVRK 118
           ++   +    +    ++   E            G   +            E    ++  +
Sbjct: 49  ITAVLLNELMKNKIKVILCDEKRNPSSELIPYYGSHDTSLKYKNQIEWSAESKE-RIWTR 107

Query: 119 MFELRFGEPA--------PARRSVEQLR---------GIEGSRVRATYALLAKQYGVTWN 161
           +   +                + +EQ             EG   +  +  +   +G+ ++
Sbjct: 108 IVYEKINNQMLLLKKLGKVEYKLLEQYLTELEWNDSSNREGHAAKVYFNAM---FGMDFS 164

Query: 162 GRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTG--KPLSFVYDI 219
                     K    N  +    S +       I++ GY   +G  H       +   D 
Sbjct: 165 --------RNKECFTNAALDYGYSIILSAFNREIVSCGYFTQLGLCHRNPYNKFNLASDF 216

Query: 220 ADIIKFDTVVPKAFEI 235
            +  +   V    F +
Sbjct: 217 MEPFR-ILVDETVFSL 231


>UniRef50_D0WRI5 CRISPR-associated protein Cas1, NMENI subtype n=3
           Tax=Actinomycetales RepID=D0WRI5_9ACTO
          Length = 238

 Score = 98.9 bits (245), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 41/238 (17%), Positives = 64/238 (26%), Gaps = 35/238 (14%)

Query: 75  LVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAP----- 129
           +++    GV   A+            ++A+  L    +     ++   +    A      
Sbjct: 1   MLFCDWKGVPEGAAFSWSSHGRVGARHRAQACLSIPRQKNAWGRIIRAKVEGQAAVLREY 60

Query: 130 ARRSVEQLR------------GIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTIN 177
            R    +LR             IE    R  +  L           R  P         N
Sbjct: 61  NRVDTTELRSLAREVRSGDPGNIEARAARLYWQAL-----WGEESFRRHPGLGSGESCRN 115

Query: 178 QCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEI 235
             +  A + L G    A+L AG +P IG  H G+  +F    DI +  +           
Sbjct: 116 SHLDYAYTVLRGHGIRAVLGAGLSPTIGLFHHGRSNNFALVDDIIEPFRPAIDSSV--SR 173

Query: 236 ARRNPGEPDREVRLACRDIFRS---------SKTLAKLIPLIEDVLAAGEIQPPAPPE 284
              N    D EVR                  S  L +L       +       P P  
Sbjct: 174 LAPNADMKDPEVRKHLVAAADQRFLPDGRRISAALDELAQHFGQYIEGELNTLPVPSW 231


>UniRef50_Q4A5I1 Putative uncharacterized protein n=5 Tax=Mycoplasma
           RepID=Q4A5I1_MYCS5
          Length = 295

 Score = 97.7 bits (242), Expect = 5e-19,   Method: Composition-based stats.
 Identities = 36/255 (14%), Positives = 81/255 (31%), Gaps = 37/255 (14%)

Query: 33  VLIDKTGIRTHIPVGSVACIMLE-PGTRVSHAAVRLAAQVGTLLVWVGEAGVRVY-ASGQ 90
           +++ K   +  +P+  +  I++  P   +S   +         L+   +           
Sbjct: 21  LIVKKENNKIVLPLSDIDTILISNPYCTISVPLINAIVSNNINLIICNKDFEPNVQLLSI 80

Query: 91  PGGARSDKLLYQAKLALDEDLRLKVVRKMFELR-------------FGEPAPARRSV--- 134
            G   +   L Q      ++ + K   K+ +L+               +    + +    
Sbjct: 81  SGYYSNKNFLSQINW--TQEFKDKTWEKIIKLKTTNYVNLIYFFGLLNKEDVEKFNFYYK 138

Query: 135 EQLRG----IEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGV 190
           + + G    +EG   + T+  L   YG T+N         +K + IN+ ++   + L   
Sbjct: 139 KIIPGDKNSMEGHIAKLTFKNL---YGSTFN-------RTDKENEINKFLNYGYTILMTY 188

Query: 191 TEAAILAAGYAPAIGFVHT--GKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVR 248
               ++  GY   IG  H       +   D+ +  +   +    +E+            +
Sbjct: 189 VSRNLVKKGYDNRIGVFHKSFNNHFALATDLMEPFR-FLIDKLVYELLIIEKNYDFINFK 247

Query: 249 LACRDIFRSSKTLAK 263
                IF     L K
Sbjct: 248 KKVFLIFEEKILLNK 262


>UniRef50_C5F1H0 Crispr-protein cas1 n=1 Tax=Helicobacter pullorum MIT 98-5489
           RepID=C5F1H0_9HELI
          Length = 285

 Score = 96.9 bits (240), Expect = 8e-19,   Method: Composition-based stats.
 Identities = 26/264 (9%), Positives = 81/264 (30%), Gaps = 38/264 (14%)

Query: 46  VGSVACIML-EPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAK 104
           +  + C++L  P   ++ A +   A+   L++                G  ++  + + +
Sbjct: 6   IKDLHCVVLESPQITITQALLSALAESKVLVLTCDRTHAINGVFTPFLGHFANAQVAREQ 65

Query: 105 LALDEDLRLKVVRKMFELRFGEP---------APARRSVEQL---------RGIEGSRVR 146
           +A+  + + K+ +++ + +                   + ++           +E     
Sbjct: 66  IAVSTESKAKLWQQIVQNKIANQASVLQSCGYITEAVELARMCEKVEADDASNVEAKAAA 125

Query: 147 ATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGF 206
             +  L   +G+ ++ +             N  +      +      ++  +G     G 
Sbjct: 126 LYFKTL---FGIGFSRKAKHKIH-------NALLDYGYVIVRSCVIRSVCMSGLLTWSGI 175

Query: 207 VHTG--KPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKL 264
            H+      +   DI ++ +   V      +      + D  V     +   S   L  +
Sbjct: 176 KHSNQFNQFNLCDDIIEVFRP-FVDRCVLGLLESRGKDGDYAVVCDLSE-LDSKSYLETM 233

Query: 265 IPL-----IEDVLAAGEIQPPAPP 283
                   IE++ +  ++   + P
Sbjct: 234 TKEDKRALIENLQSEAKVGEQSFP 257


>UniRef50_C5EZ73 Crispr-protein cas1 n=1 Tax=Helicobacter pullorum MIT 98-5489
           RepID=C5EZ73_9HELI
          Length = 230

 Score = 91.9 bits (227), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 27/198 (13%), Positives = 61/198 (30%), Gaps = 33/198 (16%)

Query: 50  ACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDE 109
             ++   G  +S   ++  A     + ++ E  ++         A +  +  QA +    
Sbjct: 39  RVVIETLGINLSSNFIKECAISKIQIDFI-ENNIQYAQLVAYNPAMTKIITMQAGIMGTP 97

Query: 110 DLRLKVVRKMFELRFGEP---------------------------APARRSVEQLRGIEG 142
             ++ + R+    +                                   ++++QL GIEG
Sbjct: 98  -KQIFLAREFIYSKIKNQRNYLKYLSKYHNIINQTILDLDRYIKKLDMAKNIKQLMGIEG 156

Query: 143 SRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAP 202
                 +             R +        D +N   + A + L+G  +++I+ A   P
Sbjct: 157 KCAVLYWNTFRHMAKF----RGFHRIKRNAKDVLNASFNYAYAILHGSIQSSIIKAELNP 212

Query: 203 AIGFVHTGKPLSFVYDIA 220
            I F+H     S    + 
Sbjct: 213 HISFLHIQNSKSLHLVLI 230


>UniRef50_B9CMG3 CRISPR-associated protein Cas1, NMENI subtype n=1 Tax=Atopobium
           rimae ATCC 49626 RepID=B9CMG3_9ACTN
          Length = 215

 Score = 85.0 bits (209), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 27/191 (14%), Positives = 55/191 (28%), Gaps = 31/191 (16%)

Query: 83  VRVYASGQPGGARSDKL--------LYQAKLALDEDLRLKV-----VRKMFELRFGEPAP 129
           + +Y +        ++L            ++  D+            R+    +     P
Sbjct: 1   MPLYGAHNTPKRVVEQLGWSEPSKKRVWQRVVRDKITHQAQVLNARAREEIGQQLFGLIP 60

Query: 130 ARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTINQCISAATSCLYG 189
             RS +     E    R  +  L   +G  ++         +    IN  +    + L  
Sbjct: 61  EVRSGDT-TNREAHAARLYFHAL---FGHEFS--------RDDETPINAALDYGYAILLS 108

Query: 190 VTEAAILAAGYAPAIGFVHTGKPLSFVY--DIADIIKFDTVVPKAFEIARRNPGEPDREV 247
                I+A GY    G  H  +   F    D  +  +   V    F+      G+  ++ 
Sbjct: 109 AVNREIVARGYLTQSGICHRSEYNQFNLGCDFMEPFRP-IVDRLVFDNV---EGDFTKDT 164

Query: 248 RLACRDIFRSS 258
           +    D+   S
Sbjct: 165 KRLLIDMLNQS 175


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.311    0.145    0.381 

Lambda     K      H
   0.267   0.0443    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,721,612,640
Number of Sequences: 3077464
Number of extensions: 68933458
Number of successful extensions: 230781
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 389
Number of HSP's successfully gapped in prelim test: 169
Number of HSP's that attempted gapping in prelim test: 229261
Number of HSP's gapped (non-prelim): 642
length of query: 305
length of database: 1,040,396,356
effective HSP length: 128
effective length of query: 177
effective length of database: 646,480,964
effective search space: 114427130628
effective search space used: 114427130628
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 93 (40.3 bits)
