Reference sequence (query): batch____ Identities normalised by aligned length. Colored by: property
HSP processing: ranked Search cycle: 3
1 [ . . . . : . . . . 1 . . . . : . . ] 180
batch____ bits E-value N 100.0% 1:180 MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYVRPLKSSADGHIVKVLEGQVCPACGANLVLRQGRFGMFIGCINYPECEHTELIDKPDETAITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKTAQGVKHFCASKQCGKPVSAE
1 UniRef50_Q3A7H8 DNA topoisomerase n=13 Tax=... 189 4e-47 1 40.7% 1:177 577:752 ISKQDVTTEKTDRICPECGKPLVIKLGRSGRFLACSGFPDCRYTEPLAGQ--EREEPVMSDQTCEKCGAPMLIKQGRYGKFLACSAYPECKNIQPLVKPKALGITCPQCGEGELMEKKSRYGKIFYSCNRYPKCKYALWDLPIEEPCPKCKFPLVVEKTTKrgTFRKCPQEDCDWTV---
2 UniRef50_B5EJ79 DNA topoisomerase n=61 Tax=... 183 2e-45 1 40.2% 1:179 577:753 VSRAEATSEALEEACPQCGKPLFLRLGRHGRFVACSGYPECNYTRPVDG---PREPAEPVGRDCPDCGKPLVYKTGRYGRFISCSGYPECKHIEPLTQPKSSGVTCPQCGEGELVEKRSRYGKVFYSCNTYPKCTYAVWGPPVARPCPRCGWPIMIEKSGKrgEQLACPQSECAFHFPA-
3 UniRef50_A0LDV2 DNA topoisomerase I n=7 Tax... 175 4e-43 1 34.1% 2:177 595:772 -SKEEVTTEQIDEPCPKCGAPLSIKLGRFGKFKACTGYPECKHTEPlkEEEVSRPEPELTDIPCDKCGKPMLIKEGRYGKYYGCSGAPECKNNQPLNKPRDTGVACPSCGQGTFLEKKSRRGKIFYSCSNYPKCKQALWDEPLEIPCPKCQAPFVTKKVTkrGTEHICVAEGCDYKE---
4 UniRef50_Q01N68 DNA topoisomerase n=7 Tax=B... 172 4e-42 1 36.9% 1:179 755:926 LEGADLSEQGEEESCENCGRPMVLKKGRFGTFFACSEYPDCKTTRQI---GGTQKKDVPLDEKCPQCDNNLVMKYGRFGEFTACSNYPTCKYVK----QKTIGVKCPECSEGDIIERRSKKGKTFYGCNRYPDCTFVAWGKPVAEKCPECGSPYMIEKFLKSGAFWQCPNAECKHQVEA-
5 UniRef50_Q2LT40 DNA topoisomerase n=2 Tax=B... 165 5e-40 1 35.8% 1:179 589:768 MKNIKREETPTDLICEKCQSPMVIKWGKNGKFIACSNYPACKNTRNIEQGEGVERSaeMTDTVCPKCGKNMLIKHGRFGRFLGCSGYPDCKHTMPIS----LGVKCPQEgdGEIIEKRTKKGRSFFGCSNYPNCTFAVWDKPIPEPCPQCNSPFLVEKYSreGSYKACPNKDCGYRDDQ-
6 UniRef50_A8ZW15 DNA topoisomerase n=3 Tax=D... 159 3e-38 1 36.2% 1:177 569:756 MRSVKGVGMDTGLSCPECGKELKIKLGKNGPFLACSGYPDCKFSRNYARTDKGTVEPVeeGKSCEKCGSPMVVKQGRYGDFLACSAYPDCKSTQSLNSGANAAPIGVKCPegDIVEKKSKRGKVFYGCSRFPKCTFASWDKPVDMACPDCGAPFVVEktKKEGTVLTCASEGCGFRQ---
7 UniRef50_Q1ILA9 DNA topoisomerase n=9 Tax=B... 154 1e-36 1 34.3% 1:172 642:807 LDTADVQETEQEEYCENCGRGMVLKRGRFGQFMACTGYPECKTTRRLDQ--AKKIPDVPLDEKCPECTRPLVLRHGRFGEFVSCSGYPECKWIK----QNFVGVKCPQCKEGEIVEKKARRGNFFYGCARYPKCDFTSANKPVAQPCPKCGSEYVLEKKLKSGTYLTCPNNK--------
8 UniRef50_Q7NGH1 DNA topoisomerase n=1 Tax=G... 154 2e-36 1 31.3% 2:180 576:748 -EEMKRVVIVTDHLCESCGRPLLNRYGRFGNFLGCSGYPECDFTHQLTRDNKPVPKDRpeGISCNQCGhpMLITYGRYGEYLKCPACG-------KSQPKSTGITCPKCSKGQIVERRSKMGKNFYGCDQYPDCDFVLWSRPIDKpcPECGSILLYKPRKRGDDMVACS--ACKFTAPAQ
9 UniRef50_C9LM02 DNA topoisomerase n=1 Tax=D... 153 2e-36 1 27.6% 4:173 599:760 ---KEENQEVSDVICEKCGAHMIVKMSRYGKYLACPNFPSCKNIKP---YHTGEEKEEISDVDCDKCGAKMVYRQGPYGRYLKCPECGQNKAIVID-----TGIECPKCHEGHLVKRRSKRGRYFYGCSRYPACDMAVWDEPVNEFCSVCGAIKVKKVRKNKEEELICSNPEC-------
10 UniRef50_D0LR99 DNA topoisomerase n=169 Tax... 153 3e-36 1 31.8% 1:179 710:888 MRDVKREEIPTDHVCEKCGAPMVIKWGRNGSFLACQAYPDCRNTkrNPDGSFEIVPEQTTDETCSECGAPMVVKRGRFGAFLACSTYPECKNTQPISLG--VDCPKDGCG-GFLTEKRSRRGKPFYGCSNYSkcDFVTWDRPIAEACPVCEASFLVKKETRRGTTVRCL--SCDYKTEQ-
11 UniRef50_Q1PYZ6 DNA topoisomerase n=1 Tax=C... 152 5e-36 1 25.1% 1:179 573:754 MKSVKGTPEESDRICNLCSKPMVIRWGRHGKFFGCSAFPECKNTMPLDE-KGEAAPPETSDQACEKCGSPMIIKTSRHGKFMACSAYPNCKNTKstTKVEPTNEKCEKCGSPMVIRFSKK--GRFMGCSGYPKCRNIKSL-PTGIKCpeCGGDLIQRYSKKGGIFFGCsyPDCDYISKE-
12 UniRef50_B5YKX8 DNA topoisomerase n=1 Tax=T... 150 1e-35 1 36.1% 1:180 578:753 ISKVIKPKekTSFKCEKCGKDMVIRWSKGVPFLACSGYPECKNTRSLNNNENGSTKKTL-DKKCPQCGAQLVVRNGKRGEFIACSNYPKCKFTQSIT----AQVKCPQCG-GDILKKQTKKGRTFWACANYPKCKFTLSNEPVPAECPKCKSSYMLKKKDRNGtfLICHNKACKGKIEIK
13 UniRef50_D1U7W1 DNA topoisomerase n=1 Tax=D... 150 2e-35 1 31.6% 4:180 622:802 ---ERETPEETGVECEKCGKPMAIKQSRRGEFLGCTGYPDCKNIVNFQRDENGAISVIESEKlcPDCGGELlkKARTGSRFIACSNYPDCTYAAP----FSTGVPCPVEgaGELVEKSSRRGKIFFSCSAYPKCDYAVWNWPVNEPCPKCGHPILTRKTTkkGEHLACPQKGCGYTREPD
14 UniRef50_B9L7D9 DNA topoisomerase n=1 Tax=N... 149 4e-35 1 35.6% 4:180 559:727 ---SQKIAKPIDETCPLCGSPLVIRKGRFGEFIACSSYPKCKYTRPLEE----SKEEKKTDVKCDKCGADMVVKKGKSGEFLACSNYPKCKNTKPLNAPEvdDVKCPECG-GDIVKRKSRRGE-FYGCANYPKCNFISKYRPVNKKCPECGY-LMAERTYRKKDVYECI--KCKHREEAK
15 UniRef50_C6HWV0 DNA topoisomerase n=1 Tax=L... 149 6e-35 1 35.8% 4:179 684:857 ---PEVLPEAPGEVCQTCGKPMIVRKGRFGTFLACSDYPACKTTRPWPpqPSPPVPLPADLPPCPACGGAMVVKSGRFGSFLSCANYPACKTTRPLP--TGIRCTRPGCD-GEIVPRRGKRG-VFYGCSRYPECDRTYPGRPVARPCPSCGHAFLMEKKTGGKLRLVCPEKDCGYEAPE-
16 UniRef50_C1ABE5 DNA topoisomerase n=1 Tax=G... 148 9e-35 1 31.8% 1:179 632:802 IGEAYDLSALETERCPDCGGKLVAKGGFFGPFVACENHPkcKYTRPIKG---EKKPAELTNYMCQECGAPMVIRHGRSGDFLGCSKFPKCRGTRSMP----TGVKCPKDGGEIAERRSKKRGKAFYGCENYPNCDFVVWDKPVAETCPECGYVGAEAKSNkrGSFRKCL--KCSN-EWD-
17 UniRef50_B0VJB5 DNA topoisomerase n=1 Tax=C... 145 8e-34 1 33.7% 1:178 557:739 IRQVDVKKEktGIVCDVCkgTMLIKHSKRGDFLSCSRFPQCKNTKNFTRDEDGNIkpTPLNENCPQCGSPLMLRTGKYGEFIACSNYPKCKYARP----KTLGIKCPECGIGELTARKSKKGRTFYSCNRYPECKYITNDKPLPISCPKCGNPYIVEKYSrkGKIKICPN--CKTEME--
18 UniRef50_A3EPL6 DNA topoisomerase n=2 Tax=L... 144 1e-33 1 35.8% 3:175 676:845 --RIVEEALPEGEVCHVCQAPMVIKKGRFGTFLACSRYPECKTTRPWPPKAEASLPAVseAPVCPECSSPMVQKRGRFGSFWACSRYPECKGTRPL----ATGHPCPVKgkGELVPRRGKRG-TFYGCSRYPECTFLLNGEPVRDPCPDCQFPY-RVRTGKKSVDLVCPNEACSH-----
19 UniRef50_A9FRC6 DNA topoisomerase I n=1 Tax... 143 3e-33 1 28.0% 4:178 619:791 ---WKPEAEKTDIVCDECGSMMLKKWGKNGWFLSCERYPKCKATRDL-SDARGTAAVRETDISCDKCGKPMIIKTGRFGDFLSCTGYPACKNTRPV----PLGVACPSCGGDLIEIrrKKGGRTFYGCSNWnkCEFKLWQKPVPVPCPQCGAKFVTRTAGKK-AMLVCATKDCGFKQE--
20 UniRef50_A6DDI1 DNA topoisomerase n=1 Tax=C... 142 4e-33 1 32.6% 4:178 559:724 ---SQKIAKPTGELCPECGNPLVIRKGRFGEFIACSNFPKCKYTRPI-----EEKEEKKVDVKCDKCGADMVIKRGKRGEFLACSNYPECKNTKPLNPPEveDVKCPECG-GDIIKRKSRRGE-FYGCGNYPKCNFISKYRPVNEKCDECGY-MMAKRTYRNKEVLECI--KCKARKE--
21 UniRef50_C6BUQ9 DNA topoisomerase n=14 Tax=... 141 1e-32 1 35.3% 11:180 624:798 ----------TGVTCEKCGSAMAIKRSNRGEFLGCTGYPDCRNIKNFERDDEGKIKVVETpgKCPDcgDLIIKHARTGSRFIACSNYPDCKHAKP----FSTGVKCPREgkGELVEKSSRRGKLFYSCDQYPDCDYAVWYPPIDGPCPKCGHPVLVKKTTrkGEHIACPEKGCGYVQGEE
22 UniRef50_C1XK22 DNA topoisomerase n=1 Tax=M... 139 3e-32 1 34.6% 15:173 578:727 --------------CPKCGRPLELKVSRFGQFLGCTGYPECKHTERLE----LKKEPEPIGEACPACGeqLVRRHGRYGSFISCSRYPECKYTRD--EAPSTGIECPKCHAGEVVQKTSKRGKPYYRCNN-PACDFLSFDPLLPDKCPLCGWNEVAKGRSGKR---ACTNPGC-------
23 UniRef50_UPI0001698F80 DNA topoisomerase I n=1 Tax... 138 7e-32 1 43.2% 1:148 217:365 VKRSDVTHEALDEKCPKCGDQLSIRLGRHGRFIGCNNYPKCDYTRDLNADKSEQDEPQveGRSCPECGSPLVIKRGRYGKFIGCSGYPNCRHIEPLEKPQDTGVSCPKCGNGTLLKRKSKRGKIFYSCSTYPDCDYAVWNEPVDGPWP--------------------------------
24 UniRef50_C1F6V0 DNA topoisomerase n=1 Tax=A... 138 9e-32 1 35.9% 17:172 661:814 ----------------NCGRVMVLRNGPWGPFMACPGypPCKTVRRL-NQKQQQKPPQPLDEKCPKCGEQLVLRHGQYGEFISCSGYPKCKYIK----QNTIGMKCPQCKVGEIVEKKARRGNFFYGCSEYPKCDFTANYKPVDRKCPECGSAYLMEKTLKSGVYLVCPNNK--------
25 UniRef50_P45771 Uncharacterized protein yrd... 137 2e-31 1 100.0% 1:180 1:180 MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYVRPLKSSADGHIVKVLEGQVCPACGANLVLRQGRFGMFIGCINYPECEHTELIDKPDETAITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKTAQGVKHFCASKQCGKPVSAE
26 UniRef50_Q9ZMV7 DNA topoisomerase 1 n=47 Ta... 137 2e-31 1 32.8% 4:180 561:732 ---SQKVHEKTGQSCPKCGGELVKKNSRYGEFIACNNYPKCKYIKQTENAN-----DEAKQELCEKCGGEMVQKFSRNGAFLACNNYPECKNTkpNAKETIEGVKCPECG-GDIALKRSKKGS-FYGCNNYPKCNFLSNHKPINKRCEKCHYLMSERIYRKKKA-HECIQ--CKERVFLE
27 UniRef50_Q5SM69 DNA topoisomerase n=2 Tax=T... 136 4e-31 1 33.1% 8:173 584:735 -------AQVPKKTCPRCGRPLELKVSRYGQFLGCTGYPECTYTEPLER-----REAEPIGEACPKCGRPLLRKEGRYGTFIACSGYPECDYTRDDG--TPTGHTCPKCG-GRVLEKRSRKGRPYYKCEN-NACDFLSFYPLLEEACPACGWPLV-----KKGEKALCLNPAC-------
28 UniRef50_Q59046 DNA topoisomerase 1 n=9 Tax... 135 6e-31 1 23.0% 7:180 592:754 ------KKAKIVGKCPKCGGDLILIRHKKGRFVGCSNYPECDVKYSLPDKGRIKIP----NKVCDACKSPILKIGDR-------EICINPECPLKQVEVKEEDRICPKCGAKLILKKG--VYGAFYGCSNYPKCKYTEPINKKEvkCPKCGGDLVV-REGKFGKFVGCSnpKCRYTEKLK
29 UniRef50_C9RG81 DNA topoisomerase I n=2 Tax... 133 3e-30 1 22.9% 7:176 750:910 ------KKAKIVGKCPKCGGDLILIRHKKSRFVGCSNYPECDVNYSLPDKGRIKIP----NKVCNACKSPILKIGDR-------EICINPECPLKQVEIKEEDRICPKCGAELILKKG--VYGAFYGCSNYPKCKYTEPINKKEkkCPKCGGDLVV-REGKFGKFIGCSnpKCKYT----
30 UniRef50_Q7MGL0 DNA topoisomerase I-related... 133 3e-30 1 50.0% 7:178 56:230 ------EHALEHTPCPQCGGELVLKHGKHGAFLGCNQYPQCDYVKPLHQNDGHIVK--ELGVACPECGNELVLRQGRYGMFVGCSHYPLCHHIEPINQPEPEQNpcPECGKGHLVERKTRFGKTFYACDNYPKCKFAVNLPPVKGHCETCGFPLLVEKKLASGVKLQCANRKCQHTQS--
31 UniRef50_B9LRP1 DNA topoisomerase n=4 Tax=H... 130 2e-29 1 25.0% 3:178 625:802 --QKSLKADKTLGPCPECGSDLLVRKSRQgyFVGCDGYPDCEYTLPLPS----SGKPLLLDETCEEHerHVKMLAGRKTFVHGCPQC---KADEADEQEDEVIGACPECGegELAIKRLRSGSRLVGCTRYPDCDYSLPLPrtDEICEEHGLPHLRVHSGDEPWELGC--PICNYREF--
32 UniRef50_C1SMY2 DNA topoisomerase n=1 Tax=D... 128 8e-29 1 26.6% 2:178 564:769 -EKQFSANLKIEMKCPVCEKDLTIKYGRNGNFVACTSYPECKFTSNYERLEDgkEEDKPSGIECEKCGKELVFKKTRFGEVLACPGYPECKNIKNYVTLPDGEIkcPKCEAGLTIK--GGRNGMFIGCKNYPDCDFTANMEVNEqkCEKCGKPMVLKK-SRRGKFFACtyPECKNAKS--
33 UniRef50_A8RBU5 DNA topoisomerase n=9 Tax=B... 126 4e-28 1 36.5% 1:137 565:695 MEKKEL--ERTGELCPECGSELVYRVGRYGKFISCINFPSCRYTKS------EEEEENASDEVCPHCGSKMVMKKGRYGSFLACSNYPTCKYIKNNKPKEEPVPtcPECGHP-LVKRKSRFGTTFVGCSNYPKCRYI-------------------------------------------
34 UniRef50_Q67PC7 DNA topoisomerase n=3 Tax=B... 126 4e-28 1 35.8% 47:180 595:728 ----------------------------------------------EEKVGGFELEDEVSDVPCEKCGRLMVVKHGRFGKFLACPGFPECKSTKPIL--EETGVTCPACGTGRIVERKSKKGgrFYGCTNYPDCNFVSWEKPVNRLCPECGAPYLVEKRIKegLSHVCKQPDCGYVEPVE
35 UniRef50_C4L7Y8 DNA topoisomerase type IA z... 125 5e-28 1 46.2% 10:178 18:188 ---------KEYRLCPECGGALSLRRSKHGLFLGCENYPDCQFMRPLQQQNVL-IEKILEDSSCPECGKLLAIKKGRFGLFIGCTGYPECSHIETNNTTLADtpDCPVCQQGQLQAKTSRYGKTFYACSNYPKCKYAINDKPIAKACPQCGFSLLVEKRTRQGIRFCCPQKDCNYSAE--
36 UniRef50_Q15ZX8 DNA topoisomerase, type IA,... 125 9e-28 1 42.0% 7:180 13:185 ------ESAFDPGPCPVCNAPLQLRHSKNGAFIGCSDYPKCEYSKPLHDSDNTEL-TVIEGSHCPECESELVIRKGRYGMYIACSNFPECHYVKSNKTQDTDKVECPSCHKGHLTKRANKYGKNFYPCDQYPQCHYALNFTPVAHACPKCAWPVMQEKKAAAGLIWQCPERKCGYKQPAQ
37 UniRef50_A7NJW2 DNA topoisomerase I n=3 Tax... 124 1e-27 1 34.5% 1:139 590:742 MRNVKREEILTDLTCPRCngQLAVKFGRNGEFLACNRYPECDFTSDFHRDSDgpASPETSDVLCDVCGRPMILKKSRFGPFLGCSGYPECKNTRRLDKQGKPAptCPKCGQGELLERRGKFGRPFFGCNRYPKCDYLVN-----------------------------------------
38 UniRef50_Q0HPA2 DNA topoisomerase, type IA,... 124 2e-27 1 42.6% 9:177 17:185 --------EKEFELCPECGSELSVKHSKHGSFIGCNNYPTCQYTRPLVQH-ESIETQVIEGSKCPECGHELAVKSGRFGIFIGCTQYPSCTHirPDQESDKPEVACPECKTGKLEHRTSRFGKSFYACSAYPKCKFIVNYPPVAETCPSCGFGILVERKGAAGMRLECPQKSCKYKR---
39 UniRef50_P46494 Uncharacterized protein HI0... 123 2e-27 1 43.6% 1:179 1:178 MNQSLFHHSKQQEYCPQCGAPLQIKQGKKGLFLGCSAYPECDYLRPLQRSEHKVLKTL--DEICPKCGNLLQLKQGSFGMFIGCSHYPECDFVVREESESEEKITCPECKTGHLISRRGRQGKIFYGCDNFPKCKFSLPAKPYSVPCPTCHFPllLKSEDGEKQIFQCANKTCRHIFEQ-
40 UniRef50_D1C7I9 DNA topoisomerase n=8 Tax=B... 123 2e-27 1 30.8% 45:177 636:762 --------------------------------------------RAEKEIGRVKVADEPTDEVCEKCGRPMVIKLGRYGRFLACSGFPECRNARPLLQK--IGVTCPQCGEGDIVQRRTKKGRVFYGCSRYPDCNFSSWEKPTGEPCPQCGGVLVETRGGT----VRCSTQGCQYRA---
41 UniRef50_C6ALU6 DNA topoisomerase I n=3 Tax... 122 7e-27 1 42.8% 1:180 13:194 MNQPLFQHTKHEEHCPQCGALLQIKQGKKGLFLGCSAYPQCDYLKPLQASLEVKTLKILE-QTCPQCGHLLALKQGHFGMFIGCSNYPDCHFveEAEDEMEEHVPCPECKEGQLVARRGRAGKLFYACNRFPHCKFSVPTKPYLVDCPQCHGNllLKKQQGEQRTWLCVNKTCRHIFTTE
42 UniRef50_B2KBN6 DNA topoisomerase n=1 Tax=E... 121 1e-26 1 31.9% 4:144 606:752 ---QRAAPKPSDEKCPLCGSPMVIRRSRFGEYLACSTYPECKGKINL-TSSGEKLAPEVTEEKCEKCGSPMVIRSGRRGKFMACSAFPKCKNTFSIDASGntKIKCEKCGKPMLL-RASKRGE-FLGCSGYPKCKTIVSVSPEE------------------------------------
43 UniRef50_C9RBU3 DNA topoisomerase n=2 Tax=B... 120 2e-26 1 31.6% 45:180 557:686 --------------------------------------------RADAAIEKVSLPDTFTDISCPRCGCPMVKKTGRYGEFLACSGYPECQMRMPVG----TGVKCPRCG-GELVKRRSKKGRYFYGCNRYPECNFVVWSEPVPEPCPECGSLMVRRGRGKKKR-VICTNESCGYQRLEE
44 UniRef50_Q5V1P3 DNA topoisomerase I n=1 Tax... 120 2e-26 1 22.6% 3:179 1123:1302 --QESLKADKTLGPCPKCGEDMLVRRSRQgyFVGCDGFPECRNTLPLPSTG---EPQVLEDHCEEHDMHHVKMLAGRDTFVHGCPRCEAEKADESEDEV---IGPCPECGsgDLAIKHLRSGSRLVGCTRYPDCDYSLPLPrtEAFCEEHDLplVIDADSDDPWELGC--PICNYEEYQ-
45 UniRef50_C0W9S2 DNA topoisomerase n=1 Tax=A... 120 3e-26 1 28.7% 47:175 562:687 ----------------------------------------------DREIPVKPQEVIVSDVKCEKCGRMMVVKTGRHGKFLACPGFPECRNTKP--YYEKIGVACPLCGHDLIVRKT-KTGRTFYGCSHYPECHFTSWDKPINETCPLCGHIMLEAVQRGGKVVHHCSNPECPN-----
46 UniRef50_B0BQ81 Conserved DNA topoisomerase... 120 3e-26 1 40.7% 4:180 2:175 ---SIFKSTKQVELCPECGSALQIKRGKQGLFLGCSSYPQCDYIKSLHQTNRVIKD---LTEICPECGHFLQLKQGNFGIFIGCSHYPECHFTVHDEAEEQEEFDCPECKTHKLVARKGRSGKTFYGCSGFPNCKFTLASKPIAKTCPQCQCSIVTLKKQRGKSMYLCANKSCQYLFSEE
47 UniRef50_C0QYG0 DNA topoisomerase n=2 Tax=B... 119 5e-26 1 26.4% 37:180 575:712 ------------------------------------HFLDTLKTATENINNMKDFFNEETDFVCEKCGKKMIKRLGRYGYFIACSGFPECKNTKGI-----SFGVCPKCG-GDITLKRSKRGREFYGCSNYPKCDFVSWDKPLQEPCPKCGGLMVEKNIKNKGLFKVCIKEDCGYSEEIK
48 UniRef50_C9LSJ2 DNA topoisomerase n=3 Tax=V... 118 1e-25 1 30.3% 47:178 673:801 ----------------------------------------------DEAIGEVEIPEEVSDVICEKCGRNMVVKQGRYGKFLACPGFPDCRNTKPLLKD--TGVPCPKCG-GRIVERRSRRGQAFYGCENYPACDYVTWDQPLTEKCPECGAFMLRHRYKNGRILPYCSNEECKTRID--
49 UniRef50_D1BMP2 DNA topoisomerase n=6 Tax=F... 117 1e-25 1 35.0% 54:173 636:753 -----------------------------------------------------EIASMESDEICELCNSPMVYKFGRYGKFLACSNFPECKNTKPIT--VGTGVTCPKCKEGEIVERKSRRGRIFYGCNRYPQCDFTLWDKPTHDFCETCGSIMVEKTYKNGTVKKFCSNETC-------
50 UniRef50_UPI00016C444E DNA topoisomerase I n=1 Tax... 117 3e-25 1 28.4% 3:178 703:897 --EMPVARELTGEKCPKCGRDMQKRYSTtgFFEGCTGypPCKYIKPRPGEAEREGP-TVTDIPCPACGKHMVRKVGRFGVFYTCEGAPDCPTTMNENAEgpTKHKCPKCEKHNLLLKESKAGKKYVQCPD-AKCKFIspVKptGVACEKCGSPMVI-KVAWRGPFLSCsyPKCRNAKS--
51 UniRef50_A1SR33 DNA topoisomerase, type IA,... 116 3e-25 1 46.2% 6:176 10:183 -----SHHKKTKELCPECASELHIRNSKQGIFLGCSNYPECKYLRPL--HEKSEIEKVLPGTRCALCGKEQVLKQGKYGLFIGCSAYPECSHtkKEIADEKESVPCPSCKNGHLIKRHSRFGKIFYACDNYPSCKYAVNDKPVNQFCPDCHWPILVERKTASTFRIICPKKGCGYR----
52 UniRef50_Q4L5V2 DNA topoisomerase 1 n=155 T... 115 5e-25 1 31.6% 45:180 558:688 --------------------------------------------RAEEEMEKVEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKT--IGVTCPKCKDGDVVERKSKKNRLFYGCSNYPECDFISWDKPVGRDCPKCNHYLMEHKKGRSSQ-VICSN--CDYKEEVQ
53 UniRef50_A5D2W4 DNA topoisomerase n=4 Tax=C... 115 7e-25 1 26.7% 47:177 566:693 ----------------------------------------------ENEIGHVQVAEEVTEEKCDRCGRSMVVKVGRYGKFLACPGFPECRSTKPLL--EPVGAKCPRCEGELVVRRTKK-GRKFLGCSNFPECEFVTWDQPSGTKCPECGGLMVEKKNAGKKGFLQCVSEDCGYKK---
54 UniRef50_B9L0B0 DNA topoisomerase n=1 Tax=T... 115 9e-25 1 30.6% 47:180 610:738 ----------------------------------------------EQTMERVRLADQPSGEVCELCGRPMVIKESRFGRFLSCSGFPECKNKRPLL--EKIGVRCPQCGEGEIVVRRSRKGRTFYGCSRYPDCDFVSWERPTGERCPQCGGVLVVSV-RRGQESVRCS--SCSYRPAEE
55 UniRef50_B0MRI8 DNA topoisomerase n=1 Tax=E... 114 1e-24 1 28.5% 30:180 562:706 -----------------------------GKFY--TGFDklTKAEKDMEGKRVKIPDEPTDIVCDKCGKPMVIKIGPYGKFLGCSGFPECKNTKRIV--NETGGLCPHCGGKMLAKK-SKKGKPFFGCENYKDCNFMTWDTPLEDKCPKCGSTLFKKVGKQGQVY--CAKDGCGYVRPAD
56 UniRef50_B1GYR4 DNA topoisomerase n=1 Tax=u... 114 1e-24 1 27.4% 1:146 569:722 LQKQKVQAQQTSEICPNCGKNMVIRYSRKVQFLGCSGYPECKTTLSLDKDGKIAAAPRETDMKCDKCGSHLIKKTgaGKQYLSCKNYPECKTLYNipEPEHTDIKCNKCGSEML-KKIGKRG-PFLTCSAFPKCRNLQWIKTNKTP----------------------------------
57 UniRef50_Q2FZ32 DNA topoisomerase 1 n=260 T... 112 6e-24 1 30.2% 19:180 536:688 ------------------EGDITWRKVIDGFF---SSFKQ-DVERAEEEMEKIEIKDEPAGEDCEICGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKS--IGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGK-TTQVICSN--CDYKEAAQ
58 UniRef50_Q9KA23 DNA topoisomerase 1 n=107 T... 112 7e-24 1 34.6% 47:179 562:689 ----------------------------------------------EEEMKEVEIKDEPTGEMCEKCGHEMVYKMGRYGKFMACSNFPDCRNTKPIVKE--IGVKCPKCEKGEIVERKSKKRRVFYGCNQYPECDFVSWDKPIARSCPKCSS-YLVEKRTKKQVQVQCS--SCDYKEEA-
59 UniRef50_B5YFC7 DNA topoisomerase n=1 Tax=D... 111 1e-23 1 29.2% 49:178 561:683 ------------------------------------------------KNFGKIQVVEKTDEFCPICGRELVIRENKHGKYYACSAYPECKYTKPIY--EEAHGKCPLCGGIVVKKKARKTGKVFWGCINYPNCSFASPYEPLDEKCPQCGSVLL-----KGNGFKKCSNENCNYIVW--
60 UniRef50_D2LPU9 DNA topoisomerase I n=3 Tax... 111 1e-23 1 25.1% 10:180 598:761 ---------REIGECPD-GGKLIYLERK--RLVVCENDGETKYYNLPKTGHIEFL-----DKKCPICGLPLIKIIRRGQSPEIRCLNSKCEYNRK----KDIVGKCPKCG-GDLVIRQSKNGKRFIGCSNYPKCDVTYSLppTGEVCPYCGAPLLILRKKGKKDWKFCPNIKCEYNRRNK
61 UniRef50_C8WG68 DNA topoisomerase type IA c... 110 2e-23 1 25.6% 13:180 637:808 ------------GPCPKCGKDLQLRASQKTrfIGCAGWPDCDVTYPLP-----KGKVEAVPEPCPTCGMPQVKVTAFRSKPRTICIDPHCSTNQ---EPDVVVGECPACKekLIAQKNPRTLKRFIRCENYDDCGTGYPLPqtEEVCEHCGAPMVIV-TTARGPWKLCPNFDCPGKEQKE
62 UniRef50_A3WII4 Zn-finger domain associated... 108 6e-23 1 38.4% 15:178 4:170 --------------CPKCGRELVVKHKGQQSFLGCSGYPDCEYTQGLREQS--EIEPESLGVPCPQCGNDLQLKSGRFGLFVGCSNYPDCDFieDPTQREQDSVPCPECEkgRVVAKTGRSGKQFFSCDQFPTCDFSLPLPPVNEACPECDFPLLMRKRSQGSERLVCPQKHCDYRSK--
63 UniRef50_UPI0000E0DBED putative DNA topoisomerase;... 108 7e-23 1 35.7% 13:180 25:188 ------------GDCPDCSNPLQIRYANKSAFLGCTTYPACEYKKSLTDNSITTIKVMV-DTPCPQCDQTLAIKKGRYGLFVSCVDFPTCNFIGSIKHQTDTKVSCPQCHTGHLLEKTNKYGKKFYSCNAYPNCKFVLNDKPVARTCPECQSTIMIE---SSATQLHCVKLTCHGVINND
64 UniRef50_UPI00006DC642 hypothetical protein CdifQ_... 106 3e-22 1 32.8% 49:179 230:357 ------------------------------------------------ENIEKVNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIM--NKIGVKCPKCEEGDIILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGS-YMVEKVTKSETKTVCSNKECNKETKE-
65 UniRef50_Q9HM08 DNA topoisomerase 1 n=4 Tax... 106 4e-22 1 21.1% 10:180 585:751 ---------QEIGDCphEGKKIMVIRDRFTYTVRCED-PSCKINFRIKRNGSITL----SDQKCPVCGLPMIKIIRKGQS----PEIKCIDPDCSYNRENEDYGECPA-DHGRLVLRQSKYGKRFLGCSNYPKCTVTYPLPqtGEVCPYCGAPILALSRNGRK-WKFCPNMQCEYNKKRK
66 UniRef50_Q18KP8 DNA topoisomerase n=6 Tax=H... 105 9e-22 1 23.2% 3:179 604:795 --QRSMKADKTIGPCPQCEGDLITRKSQAGsfIGCDSYPDCEYTLPLPS----TGKPHILETVCDVHNLQQIKMLAGKRSFVHG--CPLCEAEAADEQADRVIGTCPECNagELAIKRLRSGSRLVGCTRYPDCEYSLPLPrtDNICDEHALPALQikESDDIWELGC--PICNYREYQ-
67 UniRef50_Q12Y06 DNA topoisomerase n=1 Tax=M... 105 1e-21 1 20.9% 2:173 598:767 -EAVEADKKSHIGKCNECERVLRIVSTDKGRFVGCTGYPQCKNTFPLPKTGALAVQRSRT---CKKGGAAVLKVGSKYFWAVGIGPCFSCDMEK-ECYPPEIVGECPACDGQTFLITTK--DSRFLGCT--KRCGHTQSVPktDKVCEGCGWRLLRVKEQGKDAKEYCANRKC-------
68 UniRef50_D1B572 DNA topoisomerase n=7 Tax=C... 103 4e-21 1 36.2% 39:179 551:694 --------------------------------------PFDAQVAKGKTEIQSQKVIVFTGEMCPECGKELVRRKGRFGEFIACSTYPTCKYTQNLKKVSESAPkcPECG-GEIIERSSRRGK-FFGCGNYPKCKFISNYEPTDKKCPECGY-IMAKRELRKKEIYECI--KCKHKEEA-
69 UniRef50_D1Y390 DNA topoisomerase n=1 Tax=P... 102 4e-21 1 37.3% 47:172 639:765 ----------------------------------------------EKAPVVPPPPPELTGETCPQCGRPLVKKQGRFGDFIGCSGFPECHYIKPVQKE--IGVPCPKCggGQVVQRKSKKGRTFYGCSRYPDCDYVSWNKPAPEKCPLCGGLMEYVGRSRTPVCTKCAHKG--------
70 UniRef50_O83409 DNA topoisomerase 1 n=4 Tax... 102 7e-21 1 29.5% 57:178 584:701 --------------------------------------------------------DEKTDVVCSQCGDTMVKKLGRFGFFLACGKFPECRNTQPVPLAKCPRPAC----DGNIVGKKTRGRKEFYGCTRFPVCDFVTHFKPTFAVCPQCRCFLVEKSNRRVGTYTACVNPECRYVSP--
71 UniRef50_B3EPW7 DNA topoisomerase n=12 Tax=... 100 3e-20 1 28.0% 2:162 587:753 -NDPLLPQNTDAETCDKCggKMIIKWTASGKFLGCSSYPACKNIKPLASSRVRPKETGIKCHGCEN--GRMVLRNGRFGPFLACTGYPDckIEPPKTPPLETDLACPKCGAPLYLRTGKR--GLWLGCSKFPKCRGRQAWGQLDPAI-QHHWQEIMEKHQGE------------------
72 UniRef50_Q46AN3 DNA topoisomerase n=3 Tax=M... 100 3e-20 1 20.3% 2:173 618:787 -EAALEDKKNYIGTCKACGHVLRIVQTDSGRFVGCTGYPDCRNSYPLPKAGALTVLRSKE---CKKGGVAVLKVGNKYNWAVGIGPCFTCDLEK-ECYPPETVGPCPECDGSMFLI--NFKDTRFLGCT--KRCGYTHSVPKtdKTCETCGWKLFRLKDGDRPEEEFCINRRC-------
73 UniRef50_Q256J1 DNA topoisomerase I-fused t... 100 3e-20 1 37.6% 2:134 582:724 -KEAVIPRVVTDIDCSAChgKLVKIWAKNRYFYGCSEYPECDFKTSEEELAFNKDdeTPWDSPCPVCGGEMKVRHGRFGTFLGCLNYPKCRGTISLHKKGEepIPCPAIgsGKIFKKRSRYNKTFYSCSEYPDC----------------------------------------------
74 UniRef50_C1XZ86 Zn-finger domain-containing... 100 4e-20 1 28.8% 4:173 4:161 ---MEEVSRLPRRTCPVCGRPMEVKVSRFGQFLGCTGYPECRHTERLE----AKRAAEPIGEPCPKChgELVRRHGRYGSFISCSRYPECDYSRD--EAPSTGIECPKCHAGEIVQKISKRGKPYYRCNN---CDFLSFDRVLESRCSICGWNEIQ----KGRDKTACSNPDC-------
75 UniRef50_B1M9R9 DNA topoisomerase I n=4 Tax... 100 4e-20 1 17.4% 14:180 575:754 -------------KCPKCGTGM-RRYAKPGkfWRCTaaETCGHYMDDDKG----KPVERTAHPCPRCGETlfKRKNGGGLVWVCPAEACETFLDDVGGKPVALHTCTKCNAPLRrrETGKPTGAfwFCTDTENCKTfrPVAIKTAPCPKCGKAM-YRRKGDHGFWWGCSgeGCKTIMDDD
76 UniRef50_A8SJ74 DNA topoisomerase n=1 Tax=P... 99 6e-20 1 31.6% 45:180 565:697 --------------------------------------------RSEGDSEDYKIKDEVLDEKCPQCGKNLVIKKTKFGRFIGCSGFPDCNYIKKEVKD--TGVKCPKCG-GRIIEKISKKRKVFYGCENYPECDYAIWDKPidKKCEKCGKFLVEVKN-RFKHALKCSDENCDFEIDLK
77 UniRef50_B8E2F6 DNA topoisomerase n=1 Tax=D... 99 9e-20 1 30.0% 49:178 563:685 ------------------------------------------------KNIGKIQVIEKTDEICPLCGSKLVIRENKNGKYYACSRYPECKYTKPIY--EEAQGRCPLCGGVVVKKKAKKTKKTFWGCINYPECSFASPYEPLNEKCPQCGSTML-----KGNGFKKCSNKDCNYIVW--
78 UniRef50_D1B6D6 DNA topoisomerase I n=3 Tax... 98 1e-19 1 24.3% 2:145 602:698 -QRMTVPPELAGEDCPQCGRPLLIRRGRYGEFIGCSGYPECDFT---------KRKETSTGVPCPKCGQGTVVARKAS--------------------------------------KGKGKGRTFYGCSRYPECDYVSWSKPKGD-----------------------------------
79 UniRef50_A9BI47 DNA topoisomerase n=3 Tax=T... 97 2e-19 1 20.1% 2:180 572:719 -NKKEILHYESDVPCEKCGKNMKLNFGRYGLYLSCE---ECKETQKIPAESFGVTIKEKL-----------------------YIKEYLQETLKIDKEENKIDEKCPICG-GDLILKHGKFGE-FIACSNYPECKYTRNVK-ARGKCPNCGGDIVKLKSKKGKTYFKCN--SCSTMYWNE
80 UniRef50_A6G953 DNA topoisomerase n=1 Tax=P... 96 4e-19 1 29.7% 1:145 662:817 MAHAKAEIQPALYKCPKCGARTCYRFGRNGRFLSCTAYPECDYAAPIDRKGRPLLPERV-DIVSPEDGSSMELRNGRFGKFLASENYEKGSFVLNLDRKGneGIQCVKCDAPLNLRRGAR--GPWLGCSRFPKCRGRLAWKTLDE-----------------------------------
81 UniRef50_C9KMQ0 DNA topoisomerase n=5 Tax=B... 96 6e-19 1 19.1% 8:180 623:814 -------EVKGENVCPRChgVLTKRKGKNGVFWGCSNYPKCRMTCNDKDGKPDLEDAKAraAAPAAVSASALAWQAHPSSAQAAGGYSSAESADDIAasPADYAARMEADAKSYAAQQKKASSSwwaySASPMEHMAKDVASSDYLCPRCREGHLRSIYGRNGVFWGCSnpRCTATFDDD
82 UniRef50_O27661 DNA topoisomerase 1 n=4 Tax... 95 1e-18 1 21.6% 7:145 590:717 ------QDSRVVGECPACGGKLVIKYSPRNrfVGCSSYPDCRTVYSLPRG------ASVLKSLCEKCGLPMISYGRPRQR-----ACLDPKCGKKKSEVEEVVGKCPECGSDLI--KRSGRYGEFVGCKGFPKCRFTCSVDEVPE-----------------------------------
83 UniRef50_Q8EVZ3 DNA topoisomerase n=1 Tax=M... 91 2e-17 1 27.8% 91:180 580:673 ------------------------------------------------------------------------------------------YDTMEKISDEKVGRECPKCGKDLLYKRARRGGSKFIGCSGYPECTHLEPLEKPEElcPECGSKLLKRKSKRQQVFVGCSspKCNYIISDK
84 UniRef50_B7I2H2 DNA topoisomerase n=4 Tax=P... 90 2e-17 1 21.2% 1:146 547:661 LGKLDSAGIAAAHPCPACGKALHRRKGQYGFFWSCTGYPECKTSLPDDKGKPgkAPPPSTGFQCPKCGKELARRQGVSKP-----------------------------------KKKGMKGRpfYSCTGYPKCDASYQTGPDGKP----------------------------------
85 UniRef50_Q9JN65 DNA topoisomerase 1 n=2 Tax... 89 6e-17 1 21.1% 4:145 609:710 ---VKKVEYIEGKNCPNCSSQLVRREGRYGPFVGCSNFPKCKFI--EKSEQKAKEIVYEEGVKCELCHAKLIRRVAK--------------------------------------KKGRNKDNTFLGCSNFPKCKYTKSLEPEKD-----------------------------------
86 UniRef50_A4JTK7 DNA topoisomerase n=2 Tax=B... 89 7e-17 1 23.6% 11:133 736:859 ----------NPVHCPVCEKLMRRISGANGHFWSCTDRENCKTTLDD---SAGNPVPKVAAQPCPKCSSDMNRVRGKKGYFWSCTDREGCKNTMDDKdtRPDPIACPDCGAQMFRRERRDKKGYFWGCSAFKK-----------------------------------------------
87 UniRef50_C4NUW5 DNA topoisomerase n=12 Tax=... 88 2e-16 1 20.7% 1:145 623:728 MAKAFEGAKPPSHECFNCGGEMHRIKGKNGFFWGCQN-EACKKTFPDNRGKPEKRIAAEDCPDCPDCGSPMRLRKGKAP--------------------------------------GKKRASKFWGCTAYPDCKGTMPFKKSDF-----------------------------------
88 UniRef50_UPI0001C41D8C DNA topoisomerase I TopA n=... 87 2e-16 1 19.3% 7:167 583:737 ------QETNVVGEC-SCGGKLIKRYSPRTkfVGCSNFPKCKVTYSLPKGANMLKK------TCPTCGLPMiiKKASGKGRDHVCLDSNCGKDVSRRQAPEVVGKCPECGKDLL--KRSGRYGEFVGCSGFPRCRFTCSVDELNNLGKDKNKEDVKENKGVSKKIVR-------------
89 UniRef50_C4L6T7 UvrD/REP helicase n=1 Tax=E... 87 3e-16 1 24.3% 74:180 841:951 -------------------------------------------------------------------------RMSTFVQELIKEQQVPYEMGIEERKSIRDNPKCPRCLDGHLVIrqTNRKSTFVGCSHYPGCDYTANHPSipIVCPSCR-GYLVLRDGKNGKFYGCLnpLCKHTMERE
90 UniRef50_C6A350 DNA topoisomerase I n=3 Tax... 87 3e-16 1 18.4% 45:180 1087:1228 --------------------------------------------KEFKNKEGEIGKKLLETFLENEKNKKSKRKNVKELKPEEEKVIQVEADFENKGKEKIIVGSCPKCGGDLVVRYNRRTGKRFVGCSNWPNCNVTYPLlpTGKTCSECGNAPIIKIKERNREYEVCLDMNCNKNRKKK
91 UniRef50_Q9Z5W4 Topoisomerase n=1 Tax=Pseud... 87 4e-16 1 19.6% 2:139 284:403 -EPKQAGTPEGTPSCPRCGKPMVLRTSKRgqFWGCSGYPKCRGIIPVEVIVPAEDAGPVPTE--------------------------QAIAARPAAESPTDAPVCPKCGESMVLrrGSQKGSRFWGCPGFPKCRGMRS-----------------------------------------
92 UniRef50_A8F3N1 DNA topoisomerase n=2 Tax=T... 86 6e-16 1 22.9% 2:180 547:719 -QKWLSIDMNTNLEC-DCKSKYKLKVGRYGLYLLCEnaLETPAVFYENTMYFTHQEKESIETVCPVCGGKLEQMSGRYGNYIKCQNCGKTY-------TGFARGKCPKC-SAVVEKKISKNKRIFFKCTSD-NCDFISWLEPSNETCPECSQRLYYKKY-RSKEVLYCQN--CKKTFQLK
93 UniRef50_A1U3N5 DNA topoisomerase n=6 Tax=G... 86 6e-16 1 31.0% 96:179 619:709 -----------------------------------------------------------------------------------------------NTETPGTAIHCPKCRAPM-VEREGKFG-AFFACTRYPACKGTRPLeqKPVPCPHCFSPLVRRKSNK-GWFWGCSnpGCRQTVDD-
94 UniRef50_A4P0V4 Putative uncharacterized pr... 85 1e-15 1 48.0% 1:125 1:123 MNQSLFHHSKQQEYCPQCGAPLQIKQGKKGLFLGCSAYPECDYLRPLQRVEHKVLKTL--DEICPKCGNLLQLKQGSFGMFIGCSHYPECDFVVREESESEEKIACPECKTGHLISRRGRQGKIF-------------------------------------------------------
95 UniRef50_C6BT42 DNA topoisomerase type IA c... 85 1e-15 1 23.5% 79:180 594:712 ------------------------------------------------------------------------------EEVDGSVAQEIARVKREGINIKSSAVQCPKCKTGFLKPRKGPKGK-FWGCSAYPDCNATFPNksKEHKCPDCGKGLIRRPAKRKGLfwSCSgpECKFRCFDE
96 UniRef50_A5UN47 Helicase, UvrD/REP family n... 85 1e-15 1 21.1% 1:142 506:657 IEKneRYVIPTKLKCPVCKTGVVLlkGKLNRVLKCSHnpPFNRCNWEGGYYGSELEDLDDIEYCPSCDGILIKRYRHSdpFLGCTNFRKTGCRGKGKKLEYIGKTCPKCGKPLVKRVNGEDNSLFVGCSGFPKCRHTEPFKK--------------------------------------
97 UniRef50_P78032 DNA topoisomerase 1 n=2 Tax... 84 2e-15 1 17.8% 79:179 597:708 ------------------------------------------------------------------------------SNFKEEVKLAEGSIQRVKKEKEFVGRDCPSCASPLLYRYTKRGNEKFVGCSNFPNCKYNetLEKLEELCPECNSQLVKRRTkpNKTFVGCSnpRCRYIKKD-
98 UniRef50_B1AJN1 DNA topoisomerase I n=15 Ta... 84 2e-15 1 16.4% 47:180 533:670 ----------------------------------------------FPKVISIKFTSEMEERLDVIANGKLFWKDLVSTFIPIFEEEVKQAYTKIEkpDEKINRLCPICAHDLLIKR-SRMNTRFIACSNFPTCRFTESLEklNELCPNCSKSLVKRKNRKNKYFIGCtyPECNFIRNLD
99 UniRef50_O28469 DNA topoisomerase 1 n=8 Tax... 83 6e-15 1 23.2% 82:180 559:660 ---------------------------------------------------------------------------------RAIDYRKLSKDLREGVKKDKIVGKCPECG-GELVVRQSKAGKRFIGCSNYPDCTFTLPLPqtAKQCKEHEIKEVKIRTKKGYWNLGC--PYCNYLNWKK
100 UniRef50_C5B550 DNA topoisomerase n=1 Tax=M... 82 6e-15 1 20.3% 9:180 635:852 --------EGHGTECPHcaGHLVTqeYKGRRFLRCDNwdNCRYKTP-PEGYKEREKLEGEGNPCPACGKGVLKgpNRGRPFLMCSEVDREKPDSCQHFEWKDETPCPSCGKGVlvRKEgnKGRPFAMCsnPDGCQHFSWLDEKAAkcTVCGKGTMMRRTGrgKPFLSCSndSCDNRVFPD
101 UniRef50_A6VXG1 DNA topoisomerase type IA z... 81 1e-14 1 29.2% 6:142 29:162 -----IKSAKIRYRCPKCESLLVLKEGANGAFWGCESYPVCNYTANNENG----KPVRAKRYLCPACQSPLRRKAFKDNAFWGCSNYPECKVTVEDDNGVPSSTKKYPCRagHYLVRKKSKNGYFWGCITYPVCTNTLNDDK--------------------------------------
102 UniRef50_B5TTQ4 TraB n=3 Tax=environmental ... 81 2e-14 1 17.2% 1:180 553:740 LSTASKLTAINAIPCPKCKSQLKkkNTknQFFWICSN-EDCKHSMNDDKG----KPVEKVIHSCPKCKTGRLNktKEFFWICNDQECKHSMDDKKGQPVEKIKYPCPKCSTPLF--RSKKEGkpIWFcnRETDCKVFLPEVNKkySCPQCASD-LRRINGANGYFWGCTnnGCSATYPDQ
103 UniRef50_O73954 Endonuclease PI-PfuI n=2 Ta... 81 2e-14 1 16.8% 44:174 916:1051 -------------------------------------------REFEKKMELIMEGKLTKEEVIEEAKIRLTKILEEFKKKELEIGLELAKIVVGEEKPPLIVGKCPKCGGDLIVKYNEKTGKRFVGCSNWPKCNVTYPILQRGEIIptcgAPVVIIREKDGREWEICLDMNCK------
104 UniRef50_Q6XZ01 DNA topoisomerase n=2 Tax=S... 81 2e-14 1 23.0% 77:176 538:637 ----------------------------------------------------------------------------KEFWERFEPRIEATMELMEEIPVEKSGIECPECGND-LVYRYGKYGK-FIACSGFPKCHYIHQTGPKFGPCPECGVGEIILknKRRQRFKACTnpNCNYT----
105 UniRef50_B6YTB3 DNA topoisomerase n=4 Tax=T... 80 2e-14 1 16.7% 73:174 605:710 ------------------------------------------------------------------------KRAGTVKELSETEEKDVKKTIEKGEKTPLVVGKCPKCGGDLVVRYNRKTGKRFVGCSNWPKCNVTYPLLQRGRIIPtcDGAPVVKIREKGREYEICLDMNCK------
106 UniRef50_B1VAJ5 DNA topoisomerase n=6 Tax=A... 80 3e-14 1 25.0% 77:180 532:649 ----------------------------------------------------------------------------QTFYTNFLQLYQIADQKLEKIKPIETDQKCNLCNEGNLLIKKSHYGS-FLGCSRFPDCKNTSPWkqTDQKCNLCNEGNLLIKKSRYGSFLGCSrpDCKNIVKIK
107 UniRef50_A0LAP8 DNA topoisomerase n=13 Tax=... 80 3e-14 1 17.4% 2:145 635:744 -SKAEVTPTPNapLCPQCGGPMLQRKSPQGAFWSCAEQATCTGTRPGSphSPLMQPNPERGPLCPKCQQAPLVQRTAY--------------------------------------RGKNSGQPFWGCQRYPQCRYTQASQTTES-----------------------------------
108 UniRef50_D1BLQ5 DNA topoisomerase n=3 Tax=V... 80 5e-14 1 23.1% 102:179 666:758 -----------------------------------------------------------------------------------------------------SLPVCPKCKKGRLQQRNGKFG-AFLGCTNYPTCKHTQpdEDKQYKCPRCNVGYFVKQEVRGRTNWICSNRscKTQCSD-
109 UniRef50_C9Q4L2 DNA topoisomerase n=1 Tax=V... 79 5e-14 1 20.5% 69:180 592:725 --------------------------------------------------------------------NKIAKREESIEAFLHSVNHYIATQVDHVKTQGVPFSkcPTCQQGTLTKRKGQNG-PFWSCNRYPDCKTTFPdpSTQEFCKQCGNPLVRRPGKKEGSfwGCSgpKCTVRFFDQ
110 UniRef50_Q9PHK2 DNA topoisomerase I, plasmi... 79 1e-13 1 18.5% 13:142 561:651 ------------HPCQECGKPLRRIPGKNGHFWGCSGYPDCSVTFPDEGGKPGQKKpeVSNFACVKCGNPLK-----------------------------------------HLVKKGKGGYDFWGCSGFKecKATYEDKK--------------------------------------
111 UniRef50_Q9KRB2 DNA topoisomerase 1 n=401 T... 78 1e-13 1 19.5% 7:170 598:791 ------HIVMTNILCPTCSRPMGIRTASTGVFLGCSGyeRCKTTINLGdeEDVETAALRAKKRCPICETAmkRKLHVCGNNPNCEGFIVEEGEFKVKGYEGPTVECDKCGSDMVL-KNGRFGK-YMGCTND-ACKNTRKILKNGEVAPPKEEpyFVLRDGASGLFFAASN----------
112 UniRef50_Q1V889 DNA topoisomerase I n=1 Tax... 77 2e-13 1 23.6% 92:180 389:484 -------------------------------------------------------------------------------------------CLAKTVSIREDAKVCPKCGRLMRVTPNKKDGIHFYGCTGfnKCTYSENIKVKE--CPSCGNDVVKKKNRKEGtfLACLgpQCHYTENLE
113 UniRef50_D2EGP7 DNA topoisomerase n=1 Tax=C... 77 2e-13 1 22.4% 99:174 606:688 --------------------------------------------------------------------------------------------------QQYIFGTCPKSGGKLKLVVSKKSHKRFVGCSDYPKCHFGMPLPqsPQSCPKCGIHMIehAKESKRTYIFCVNPACK------
114 UniRef50_O58356 DNA topoisomerase 1 n=2 Tax... 77 2e-13 1 20.0% 105:174 605:679 --------------------------------------------------------------------------------------------------------KCPKCGGDLIVKYNKKTGKRFVGCSNWPKCDVTYPILQRGEIIptcgAPVVIIREEDGREFEICLDINCK------
115 UniRef50_P40114 DNA topoisomerase 1 n=47 Ta... 76 4e-13 1 18.6% 7:146 597:729 ------KKQIEVCQCP-CGNGIIL---DRGKFFGCSNHPNCNKGLPKRVKEKTIPTAQVKKLFEENKTDIIKGFKSNGKEFSAYLAFVNGEVSFNLPSVEesLGQCPKCQKGKILNR-----KTFFGCSEYQncDFMLPAKIKGKK----------------------------------
116 UniRef50_Q5ZHE3 DNA topoisimerase n=9 Tax=r... 76 5e-13 1 16.3% 94:179 620:720 ---------------------------------------------------------------------------------------------DNGLNMKIDTHPCPSCGKPLRRLKKKDKNEYFWGCTGFAdcKFACDdkPVPrkCMACGHGLSRRPGKKRGMfwGCSnpTCKQTYPD-
117 UniRef50_D0Z5F5 DNA topoisomerase n=1 Tax=P... 75 7e-13 1 27.6% 83:180 605:720 ----------------------------------------------------------------------------------GFVAHYVDKVKTNGVNITVETFDCPNCADGHLIKRNGSKG-VFWSCNRYPECKTSFPDKssEFNCPLCQKPLVRRKGKseKYFYGCsyPQCKASYQEQ
118 UniRef50_Q1Q866 UvrD/REP helicase n=4 Tax=G... 75 9e-13 1 20.9% 2:140 842:954 -SKSFQERHRKIFKCPNcnGYLRLIKGQYGSFYSCSSGKGC---------------SVGKARVCTKCEAPSVDRE--------------HESLCNNRDCGNSMKICNKCGRPMKM-RESKFGK-FWGCSGypdcKNTIKI----------------------------------------
119 UniRef50_Q2BNY9 Helicase IV n=1 Tax=Neptuni... 75 1e-12 1 22.9% 5:144 839:952 ----KEQSEAKERRCRSCegTLIKREGPHGTFMGCSNYPLCNY----------------KESTCPRCNSTM----NNSNEYRICSNSSCSWWI----------PICPECGGNLMM-RESHYGK-FWGCENYRscHRQKFIEPPE------------------------------------
120 UniRef50_A3M2F6 TraB protein n=2 Tax=Acinet... 75 1e-12 1 19.3% 15:180 576:741 --------------CSKCSEQLVNMTSANGkyFKCTNL-KCGHMMMNQDGIAIDRESLTSEFKCIVCESGLISRSGQNGEFFGCSGFF-----KKRNKCTASYQKKPDGTPDYQAFLAKRELKESKQEQGEKPVPKNTEKKEKEFNCPECKA-LLQQRTGKSKtiWSCSSPNCKNEYWGE
121 UniRef50_C2XKX2 DNA topoisomerase n=7 Tax=B... 75 1e-12 1 20.7% 7:146 621:753 ------KKQIEVCQCP-CGNGIIL---DRGKFFGCSNHPNCSIGLPKKIKDKTIPAVQVKKLFEENKTDLMKGFKSNGKEFSAYLAFINGEVSFNLPTVEesLGQCPKCQNGHILKRD-----TFFGCSAYQscNFAISAKIKEKK----------------------------------
122 UniRef50_B9NSL7 UvrD/REP helicase n=1 Tax=R... 75 1e-12 1 24.0% 8:136 867:966 -------RLNEPHTCGECGGHLLAFPTKDGGMwrCEHADLCGFSINA----------------CPSCGIGLPEQDGEAGP-------------MKCRNCGAEYPACPECENGWLVERKSRYGK-FLGCVSFPRCKG--------------------------------------------
123 UniRef50_A7ZI15 Helicase, UvrD family n=1 T... 74 2e-12 1 21.7% 14:133 886:978 -------------HCPDCESglTGKVSRykKFYVCSHSPACDYM----------------ASACKQCSSPMVMHNG-------------LQRICANPECQEIEIVCRRCGLGTMLKRKNKDGGVFYGCNRYRR-----------------------------------------------
124 UniRef50_A3X5L1 Helicase IV n=1 Tax=Roseoba... 74 3e-12 1 21.8% 14:146 825:928 -------------PCSECGGRLLPVPARDGrwYRCEHNLMCRNYMPA----------------CSQCGIGIPTVSGASG-------------ILECSHCGASHHECPKCSDGWLVERHGPYG-DFFGCIRYPDCTGKANVSEVRSR----------------------------------
125 UniRef50_Q64CK3 DNA topoisomerase n=2 Tax=e... 74 3e-12 1 30.7% 106:180 592:671 ---------------------------------------------------------------------------------------------------------CPKCDSDLLLL-SSRRGKRFVGCSNYPACEFSLPMPktEDKCDEHPykLKIIKKGARPWDFGC--PYCNFQQWQD
126 UniRef50_A4WTK0 UvrD/REP helicase n=8 Tax=R... 73 4e-12 1 26.8% 8:134 863:959 -------AQTENHVCGECGGRLLGVIGKDGrwYRCEHAQHCGNLLPA----------------CPSCGAALPRRNEEAAEVR--------------CGCGASYPTCPECRDGWLVERAGSFGR-FLGCVRYPTC----------------------------------------------
127 UniRef50_C7DGI7 DNA topoisomerase n=1 Tax=C... 73 5e-12 1 24.1% 87:173 579:670 --------------------------------------------------------------------------------------EKISEEMKESFKSANVLGKCPK-DGGDLVIKRSFRGKQFVACSNYPKCTNTYPLppTGNACEFCHTPIVKIIRRGKPPFEIDLDPNC-------
128 UniRef50_C4LDL2 UvrD/REP helicase n=1 Tax=T... 73 6e-12 1 22.0% 7:133 886:985 ------KAEIGLWNCPSCESglLAKNSHYGrfYICSLSPACNHTTN----------------SCKQCGSPLL-------------NHPEVLRICANDACQDIEVGCHRCGIGTMVLRKNKNGGTFYGCNRYRQ-----------------------------------------------
129 UniRef50_UPI00006CC0A9 DNA topoisomerase family pr... 73 6e-12 1 14.9% 12:179 667:837 -----------NERCPLCNFQVLEVTTDKGI-----SYNICPSCYNNPPYEQDIENSNANSEDSNFKKTSMP-----------CYKCINKNCSLSGGLKNISLYNCPCCNSPIQIRETKKDKKQFIGCTKYPDCDWSVFLppTSQECQSCKEnlVEVKFEEGGQYdiCVYPGCNSSLKE-
130 UniRef50_UPI0001BCB37F UvrD/REP helicase n=1 Tax=F... 73 6e-12 1 21.0% 90:170 924:1001 -----------------------------------------------------------------------------------------FDNEEMTLDEYGEKRICKACGSHMIKRKNSITNEEFYGCYHYPKCDYTEPLENINI-CPICGSKLLKSKFEENSYY--CNN----------
131 UniRef50_Q481U8 Helicase IV n=1 Tax=Colwell... 72 6e-12 1 16.4% 7:146 922:1037 ------QSLVDDLHCLACkgLLKKRTGRFGTFYACSNSPRCEH----------------KEKPCAKCESPMTRKR------------YPGFKTCLNDLCKSLIPTCSLCDAEMVLRTSKK--GEFWGCRNYksCKNGVDNANVNWP----------------------------------
132 UniRef50_A1WZY5 DNA topoisomerase III n=6 T... 72 7e-12 1 21.5% 88:180 612:721 ---------------------------------------------------------------------------------------DKNQEFKILDNENKPKIQCPQCNKGFLTKRKGKYGN-FWGCSEFKqcKAIYPDNktTHKCPQCNKGFLQRIKSKNgwWWGCskQGCKAMYYDD
133 UniRef50_A0CUH3 Chromosome undetermined sca... 72 7e-12 1 13.9% 15:180 690:857 --------------CNICGTQLVEIKQINGTFlcCLGQEKSQNFNSIQNYQPQSQNYNSMSNFQPKSQN---------------NNTSNFQQKFFKSSNFEETFKCNQCQNQMKIRQSKLKNSYFFGCLGYPQcdYIKSIQRTDKKCRKCNSNIFQTEYSENSTflLCLYPECSEGFKTE
134 UniRef50_B1VJ64 DNA topoisomerase n=9 Tax=G... 71 1e-11 1 25.2% 11:125 631:751 ----------NGTPCPVckGFLIKRKGQNGFFWGCSCYPECKTAFPDKNGQPVTEKQPNEGAvcPSCSNEIIIRP-KGYFCTGCEFKIWAEFCSKKLTQNQVEKLIKDGKTAVIKGFKTKAGKTF-------------------------------------------------------
135 UniRef50_B1L3G6 DNA topoisomerase I n=1 Tax... 71 2e-11 1 25.0% 11:130 593:698 ----------SLGKCPECGGDLNMRKSSYGYFIVCSNYPecDVKFNLFKN------ERFEGKFC-ECGLPLVSGRIKTKSNRGRG------YTRCIANCDRTPLRCAKCGGPMVA-KQGKFG-VYLKCEN--------------------------------------------------
136 UniRef50_C1DJ79 DNA topoisomerase I and res... 70 3e-11 1 18.7% 16:138 153:284 ---------------PDGGVDLIVRKGRKRYLVQCKQWRALKVGVKVVRELYGVVAAQGVAGGFVVTSGSFTEDARQFAATcgETLQSWISMVSGRPAPEPSSRHCPLCRSPMvvKRGGKAGTHFWSCSNYPDCRGTR------------------------------------------
137 UniRef50_D2RGC8 DNA topoisomerase n=2 Tax=A... 70 3e-11 1 19.2% 75:173 550:648 --------------------------------------------------------------------------KSVDRERLGSIIKEGIEKDREEEMEKNAIGSCPECGGVLLVKRANKR---FIGCSNYPKCKFSRPLPQKgkVCEKHGVKILRIVEKDRKWEF-C--PLC-------
138 UniRef50_C6AVQ0 UvrD/REP helicase n=2 Tax=A... 70 3e-11 1 24.4% 10:136 864:960 ---------EKTQECGECGGRLLVARGQDDRMwrCEHVQHCDNVLPACQACGTALPRPKVGSQEVSCG------------------------------CGANAPKCPQCKDGWFVERSGRYG-PFLSCVRYPSCDG--------------------------------------------
139 UniRef50_Q9LVP1 DNA topoisomerase n=6 Tax=E... 69 7e-11 1 17.3% 13:180 640:843 ------------RRCNLCnsDMALRKNRDGNfvGCMNYPQCRNAVWLPG---PTLEASVTTNVCQSCGPGPVYKILFKFRQIGIPPGFDVNHLGCVGGCDDILKqiDICGTGSRSqrQSnrGHASTNcsRVPASRNSRPTATNPRncNTCGSQCVLreANRGRQFFSCPTQGCSFFAWED
140 UniRef50_C9RSM0 DNA topoisomerase n=49 Tax=... 69 8e-11 1 23.4% 2:125 572:680 -EQVYKAPNLTNLTCPECGALLKERKTKDGRMLVCSNL-ACRYRRR--------RDPKLSNRRCPQCHRRMEMHEGKAGMYFQCRPCNIVEKADETKRIAAKGSERA------LLKKYSPANESF-------------------------------------------------------
141 UniRef50_UPI0000E88005 helicase IV n=1 Tax=Methylo... 69 1e-10 1 20.9% 13:141 853:955 ------------RVCPLCksPLTEKTSKDGrfFGCQNWDLCLYT----------------SAPCQLC-------------NIGYLEKHDTYFSCDNKHCKHQAESCPKCGDGYLHQKPGEFG-LFLACSNynNCDFTKNLS---------------------------------------
142 UniRef50_C0QM75 Multiple domain fusion prot... 68 1e-10 1 30.7% 105:179 399:473 --------------------------------------------------------------------------------------------------------PCPICLDGKIVSETTSKNKTYYTCSN-RACRFVSWEKPYHFECPLCKNPFLTEFTTPSGDklKCPRASCTYSQNN-
143 UniRef50_Q8K9P7 DNA topoisomerase 1 n=2 Tax... 68 1e-10 1 17.0% 8:178 582:729 -------TVPTEIDCSLCNKKMGIKTAVTGVFLSCLGY-----------------NSEPNEKRCKNTINLISL--------------NDLSTTKKEEKNFHLKNRCKKCNLVMDVYLINENLKIFI-CINNPSckKSLNCSLKKIKCEKCKNDML-FKTGRFGNFFMCINDTCKNTRK--
144 UniRef50_A4J356 DNA topoisomerase n=3 Tax=C... 68 1e-10 1 14.0% 11:167 614:772 ----------TLGKCPVCGRDVVE----TAKSYGCSGYKecKFAIWKEINSKKISAKQAETLLTKGKTGLIKGFKSKAGKTFDAlgFANAVNDQPGSTGNTALGKCPLCGKDVVE------NSRSYGCSGYKdcKFVIWREIAKKKITQTQAIELLAK-GKTGIIKG-------------
145 UniRef50_UPI000174264A helicase, UvrD/REP family p... 67 2e-10 1 15.1% 36:154 563:685 -----------------------------------TDDPIISLLLSAPEACRFAEERRLFYVALTRTKNKVYLMVSENESLFAKEIKQYSNYLIQGRYGETDLVNCPWCKTglVIRKNSQTGKNFVGCSHYPNCNQSYniLSKPILCPACQSGF--------------------------
146 UniRef50_Q1AUL7 DNA topoisomerase n=1 Tax=R... 67 2e-10 1 23.2% 85:179 574:673 ------------------------------------------------------------------------------------SEEKFADIVWNGIRGDETLGPCPNCGRNLVVRRNRRNRKRFAGCEGYPECRTTFPLppLGTACEACGLPEI-KVLGGRRPWVTCINMDCPKKQEQ-
147 UniRef50_A3D9J8 UvrD/REP helicase n=11 Tax=... 67 2e-10 1 14.5% 2:146 875:995 -STSLVQRLFKEVKCVRCSTGMLkrTGNFKSFYSCSHFPLCDH----------------KEQGCELCASPMTRNHFAGFKVCLNEAC------------GHISPLCNLCGGDMQL-KDGRFG-PFWACRNypSCTNTLNKAKLSIP----------------------------------
148 UniRef50_C6P2V7 DNA topoisomerase n=2 Tax=P... 67 2e-10 1 30.6% 8:105 580:676 -------TEILEETCPKCGKPLSKRLGKRGSFIGCTGYPECDYTRSLGG-EEDAGESRKELGQHPDTNQLVLLLRGPYGPYVQLGEMIEGEKTKPKRVSWPKELP---------------------------------------------------------------------------
149 UniRef50_D0NS69 Calpain-like protein n=2 Ta... 67 3e-10 1 16.6% 4:166 1023:1181 ---VDAYRERNTPVCVDCHQRIEVVEGRfgRMfgSSVHAECIDAYQIR-----------TSEKCIHCGHAIAAIPGRFDGKYYQVNGGKCHGECMEEYQMATAQRCVHCTEP-VIKIAGKFDGRFYKIEGERLVHFECWeqSVAPKCVHCAQPILQIPGRFDGRFY--------------
150 UniRef50_B7DM26 NERD domain protein n=1 Tax... 67 3e-10 1 45.2% 5:46 204:245 ----EMKRQLAANICPRCGGELRIRKGQRGEFYGCSNYPRCRFTRP--------------------------------------------------------------------------------------------------------------------------------------
151 UniRef50_Q4QPE8 DNA topoisomerase n=23 Tax=... 67 4e-10 1 35.8% 1:53 608:660 LKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFFGCSAYPNCQHIENIDSKKNT-------------------------------------------------------------------------------------------------------------------------------
152 UniRef50_A7I6L6 DNA topoisomerase n=5 Tax=M... 66 6e-10 1 16.7% 42:179 530:670 -----------------------------------------EMTQTIESHMQQIKESKRTRDDVIAESRSMLHKAFDQLEANEQVIGND---IRDRTAEELNLGRCPACG-GTLAIKHMRGSTQFIGCSRYPECTFNiwAVRTDDICDKHHLHFVRlrKGARPWDIGC--PLCHHISSN-
153 UniRef50_Q2RKN9 DNA topoisomerase I n=1 Tax... 66 6e-10 1 19.6% 85:176 938:1038 ------------------------------------------------------------------------------------VQKHRLTELADALKKRMAFPSCPLCG-GTTGLRTGKHG-PFFGCASFRncKGLINIPrlELTCPHCG-GKVVLKSGRNGAFLGCsyPDCRWT----
154 UniRef50_Q0W2I3 DNA topoisomerase I n=2 Tax... 66 6e-10 1 17.8% 7:113 581:689 ------AADSDIGPCPLCGSALVVRERkkNKFIACSGFPNCRNTYNVPPGTLKFDKTVCEKHRLHHVKVTPPSTKGPDGKAVRGKAYDFGCPACRKENPSVMPPCVKTCKPDL-------------------------------------------------------------------
155 UniRef50_D1AS14 DNA topoisomerase type IA c... 66 7e-10 1 13.9% 2:167 606:762 -NKDIKIRHKDDVICPKCngFLKNIKTSKYNFWACSE-EKCGSTFNdkPDFTEKRPAEKSEIPCPKDGGILYKIKGKYGDFWKCKTCQQNYKDSnpKKEMKKSAQKCDCGEFLTEIPTKKDPNKIMLC------------------CEKCNSKYFEQADESIKKWVI-------------
156 UniRef50_B8FJQ0 DNA topoisomerase type IA z... 65 1e-09 1 28.4% 105:178 352:425 --------------------------------------------------------------------------------------------------------TCPLCGEGKVKEQQTSMGKIFFACTS-KSCQFISWGKPHHIPCPLCSNSFLVEAQAIEgaILKCPRATCSHVQP--
157 UniRef50_Q39UP7 DNA topoisomerase I:Restric... 65 1e-09 1 20.3% 96:174 233:336 -----------------------------------------------------------------------------------------------IFPKAVSSPNCPKCGAEmvARQGSNAGREFWGCSTYPKCKGIVPVTINQDtcPQCGEELVLRQFQsgQQFYGCL--TCK------
158 UniRef50_Q185E5 DNA topoisomerase n=10 Tax=... 65 1e-09 1 16.1% 2:125 579:692 -DNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICE----------DRECNTRKTISQVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYLKNQNKNQETF-------------------------------------------------------
159 UniRef50_C6XEP4 DNA topoisomerase I n=1 Tax... 65 1e-09 1 42.6% 3:49 542:588 --EIPRPAPSTVGSCPKCGKGMVQRTGSRGPFLGCSGYPKCKETQQLPK-----------------------------------------------------------------------------------------------------------------------------------
160 UniRef50_B0TT01 UvrD/REP helicase n=4 Tax=S... 65 1e-09 1 22.7% 15:142 896:1002 --------------CPQceGKLIPREGRFGLFYTCsgQDYCDTKIDA----------------CSVCNSAPMLRNET-------------HHFCSSEKCGHRLPVCPECISGKLVVrnSKSGKSFLACSGHKrcQYTCNLAE--------------------------------------
161 UniRef50_A8SXH4 Putative uncharacterized pr... 65 1e-09 1 39.5% 2:44 1117:1159 -EEAKSAPAKMSMICPECGKKLVERSGKFGKFIGCSGFPKCRFT----------------------------------------------------------------------------------------------------------------------------------------
162 UniRef50_C6CZS8 DNA topoisomerase n=5 Tax=c... 65 2e-09 1 22.3% 3:105 594:687 --KEYKPHNLTHSRCPECGKLLMEVKGKRGKSLVCSD-RECSYRR--------QAEPALSNKRCPQCHKKMEIHNGKAGKYAQCRPCNVIEMLGDKQGGRVNKHQ---------------------------------------------------------------------------
163 UniRef50_A7VHI2 Putative uncharacterized pr... 64 2e-09 1 38.3% 2:48 202:248 -QNIRKNNKEVQRICPKCGGKIVYKRGKYGKFLGCTNYPNCRYTKEMK------------------------------------------------------------------------------------------------------------------------------------
164 UniRef50_A8U7S1 DNA topoisomerase n=2 Tax=L... 64 2e-09 1 20.3% 3:120 577:680 --ETYKDHALTTKICPDCGELLKERSGRDGKMLICSS-TTCSYKRRKD--------PKVSNHRCAQCHRKMEIHEGKNGNYFKCKYCNITEKIEGKSSKKPSKH-----ETSKLMKKINK------------------------------------------------------------
165 UniRef50_C3QAX1 NERD domain-containing prot... 64 2e-09 1 36.4% 3:46 202:245 --QYRSSRLINQGVCPQCGGHLILRKGKYGTFYGCSNFPTCKFTIN--------------------------------------------------------------------------------------------------------------------------------------
166 UniRef50_UPI0001C36AB7 DNA polymerase III, alpha s... 64 2e-09 1 48.8% 5:47 220:262 ----KLLKDADIPVCPRCGGELTKRNGKFGPFYGCSNYPACRYTKNI-------------------------------------------------------------------------------------------------------------------------------------
167 UniRef50_C5QM86 DNA topoisomerase n=2 Tax=S... 64 2e-09 1 14.2% 2:121 588:690 -EQKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQD-PSCKTKKNIQR---------KTNARCPNCKKKMTLFGRGKEAVYRCVCGHSETQAQMDKRMKEKS-------SGKVSRKEMKK-----------------------------------------------------------
168 UniRef50_Q28MI5 DNA topoisomerase n=13 Tax=... 64 3e-09 1 30.9% 90:144 616:670 -----------------------------------------------------------------------------------------EPHLFPDPGDGTDPRLCPNCGVGRLSMRTARAGGAFIGCSAYPECRYTRPFGPPD------------------------------------
169 UniRef50_A7B5W2 Putative uncharacterized pr... 64 3e-09 1 34.8% 2:47 174:219 -EMAKLQKKSVVFVCPKCGGEMIRRNGRYGEFWGCGNFPKCRYTQNI-------------------------------------------------------------------------------------------------------------------------------------
170 UniRef50_C7NZB3 DNA topoisomerase type IA z... 64 3e-09 1 20.0% 6:170 95:243 -----SEAGIPVGDCPACAGTLVRSNGA----VRCSN---CAERYGLP------ADATITGGRCRDCRLP-TIRTERGRAFELCLDRECESLDDRVIDAFDREWACPECDGDLRIVRK---GGLFAGCEHHPDCefAIPTGVVVDTC-ACGLPLFETAGGRRCLDATCSQ----------
171 UniRef50_B2UHD2 DNA topoisomerase type IA z... 64 3e-09 1 43.8% 1:48 272:318 LAKVFEGDSRT-PSCPACGVKLVARNGKSGAFWGCSNFPKCWNRLEMK------------------------------------------------------------------------------------------------------------------------------------
172 UniRef50_A5G3C3 DNA topoisomerase, type IA,... 64 3e-09 1 20.7% 85:142 200:260 ------------------------------------------------------------------------------------ERHKQNQTDPSDRTDRSEKKLCPACGKPMVLrkGSNAGSQFWGCSGYPECKTTLPVQP--------------------------------------
173 UniRef50_Q702B0 DNA topoisomerase n=1 Tax=u... 64 3e-09 1 17.1% 98:179 612:701 -------------------------------------------------------------------------------------------------RVEMSYGKCPKCHIgmVLIKSNKTKKRFLACSKFrgCKTITIVPqdNSVC-TCGWPILRIIFKRFSPRKICVNRSCRENLSN-
174 UniRef50_Q5HLZ4 DNA topoisomerase 3 n=9 Tax... 63 4e-09 1 13.3% 2:121 587:689 -EQKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQD-PKCKTKKNIQR---------KTNARCPYCKKKMTLFGKGKEAVYRCVCGHTETQSQMDKRMRDKT-------NGKVSRKEMKK-----------------------------------------------------------
175 UniRef50_UPI0001BC8A6C UvrD-like helicase IV n=1 T... 63 4e-09 1 23.5% 90:174 159:233 -----------------------------------------------------------------------------------------QEFAASPEQKNAIATNCPVCTQGNLVNRRNKtgSSFIACSNWPRCTHT------ESGCRQCDAPMV-----RSGRYRLCTAPACS------
176 UniRef50_Q5WAX6 DNA topoisomerase 3 n=137 T... 63 5e-09 1 16.5% 4:124 599:710 ---TFRHDNKTGEKCPECGKFLLEVNGKKGKMRVCQD-RECGYRKNI---------AMTTNARCPKCKKKLELRGEGEGQVFACVCGHREKkqFEQRRKQNKHKNVSKREVQSYMKKQNKQDQF--------------------------------------------------------
177 UniRef50_B4EXZ8 DNA topoisomerase n=4 Tax=E... 63 6e-09 1 24.2% 2:63 612:673 -EMPLALDLPPMPSCPSCHGKMVLRESSKGRFWSCQRYPDCKGSVPLPEKMQGVTRGMNKRKK---------------------------------------------------------------------------------------------------------------------
178 UniRef50_B0P1A6 Putative uncharacterized pr... 62 6e-09 1 19.7% 39:175 795:939 --------------------------------------PSTQAGFKEERVKYRPIIRFKGANTASAIYGFMEMNKTIDESNAETDSEEEETDENTFAAYIRLHKKCPKCGKPMQLKK-SPKGKFFISCIGYPGCKTTEFVKatGQKCVRCKYSLTAEKSrgGGLYIHC----CGY-----
179 UniRef50_A6EQS9 Hypothetical membrane prote... 62 6e-09 1 40.0% 4:48 208:252 ---NERNKKEKQRICPKCENQLIEKSGKYGKFYGCSNYPKCRYTLKIK------------------------------------------------------------------------------------------------------------------------------------
180 UniRef50_D2VSX3 Predicted protein n=1 Tax=N... 62 7e-09 1 14.3% 4:150 680:807 ---SKSEYESIEDVCPICNFQILNIITQKN-----TSYKLCPHCFNNPPEIENSNESFANGFKCFNCT---------------------FTGCKYSRKKDAVVRKCQKCSNNLVVRQRKNDTSLYIGCKGFPNCKSAVWLPktTEKCNRC------------------------------
181 UniRef50_C7GB94 Transposase n=5 Tax=Firmicu... 62 7e-09 1 13.3% 41:175 28:168 ----------------------------------------CRYIPLKQWTFDDSHSPKYQKFKIDKLPVIKTFIKQDWQFLLEYYQWKYGKPVKPVQRRnsEDTVCPLCEAPHHYIYDNNGGNGQYQccGQTFCSGEVVTTPFRLTCPHCRNTLVPKKDRKFFRIHKCVNPKCPY-----
182 UniRef50_C7RD81 NERD domain protein n=4 Tax... 62 7e-09 1 50.0% 14:49 218:253 -------------ICPKCGGKLVEREGKYGKFIGCSNFPKCRFVVSQNK-----------------------------------------------------------------------------------------------------------------------------------
183 UniRef50_A0R979 DNA topoisomerase 3 n=95 Ta... 62 7e-09 1 18.5% 2:120 601:710 -DKKYKHDNISTKSCPDCGKPMLEVNGKKGKMLVCQD-RECGHRKNV---------SRTTNARCPQCKKKLELRGEGAGQIFACKCGYREksTFQERRKKESGNKADKRDVQKYMKQQKK------------------------------------------------------------
184 UniRef50_Q1UZD4 DNA topoisomerase n=4 Tax=B... 62 8e-09 1 18.1% 74:167 567:671 -------------------------------------------------------------------------KEKRTREVLDLLNDSLGSLIFERDADGNINRQCKLCDSGSLSLKNSFRGGAFIGCSNYPDCKFTRPLSKAKAAAqhENGNDMYLKNGRFGPYLQ-------------
185 UniRef50_A0RYH5 DNA topoisomerase I n=1 Tax... 62 8e-09 1 20.6% 46:176 68:207 ---------------------------------------------PAPRRRAGPRHTVRAGRSAAEALKKEIKQYYDANGFLSWSAARKKYVILGTSEPTNGLVRCPECGTGQLVVVRSRtrKRFLGCSNynGCAASAPLLqlKRACPGCGWPIVMFRYSRKQSwkQCANRECDTR----
186 UniRef50_D2J7M2 Putative uncharacterized pr... 62 9e-09 1 51.2% 7:47 161:201 ------PDFSNNEKCPRCNHKLVVRTGKNGQFLGCSNYPNCKYTKNI-------------------------------------------------------------------------------------------------------------------------------------
187 UniRef50_C5S684 DNA topoisomerase type IA z... 62 1e-08 1 47.2% 12:47 367:402 -----------TPTCPYCGSSMRLRSGRYGQFWGCSQYPGCKGTRNF-------------------------------------------------------------------------------------------------------------------------------------
188 UniRef50_A4HPI6 DNA topoisomerase n=9 Tax=T... 62 1e-08 1 19.0% 6:179 669:841 -----LEPVNPPHTCPLCGFVVLRVTNREKQ----TSYHVCPHCFGSPPRAWNVTG-------CGTAGADALLPDIEAAAEFRCFQCTADCPLAKGLEA-IGITTCIACHQHELRLRPGPNG-FFLSCRGYPSCHLSVSlpSPSQRCPACNAVLLTFDFSGRqlDTICI--RCDARIKD-
189 UniRef50_A4VK17 DNA topoisomerase I: Restri... 62 1e-08 1 19.3% 29:142 181:297 ----------------------------KGGFIVISGRFTEDAKVFAQGKNLRLIEGAELNEMIRQSRAAVARQNSQATISKAPYQPTSVTPDPLAQPPRGTQPICPTCHAPMVQrrGSNVGNTFWGCSQYPKCKTTRNEMP--------------------------------------
190 UniRef50_A1VWJ4 UvrD/REP helicase n=1 Tax=P... 61 2e-08 1 18.5% 66:146 829:908 -----------------------------------------------------------------RATVTLITITLKESAFVKELVREHQITVRMADGTESSNELCSVCGDGFVVPKNGKYG-AFLGCSNYPRCRHTRNIEQNEVR----------------------------------
191 UniRef50_B3PMD8 DNA topoisomerase I n=3 Tax... 61 2e-08 1 16.9% 79:161 537:618 ------------------------------------------------------------------------------NRFQRSYDDASKTIEISIMPQEFLERSCPRCGSTLLYRNNSKKHTKFIGCSNFPACRYSENADGTPTG-QKTYKPRYYKKSSK-------------------
192 UniRef50_C6PBC0 DNA topoisomerase type IA z... 61 2e-08 1 43.8% 1:48 858:905 LNKSNGIGDVVDKRCPKCGNPMIIRKGKYSIFLGCSNYPICKCAVGLK------------------------------------------------------------------------------------------------------------------------------------
193 UniRef50_Q6YRP6 Slr6108 protein n=1 Tax=Syn... 61 2e-08 1 25.8% 2:63 197:263 -NQYQNADENTAPECPKCGKNMVLRKSKSGpfWGCSSYPQCRGIVNIKTAEEKAADDINKMHK---------------------------------------------------------------------------------------------------------------------
194 UniRef50_A7HZT1 DNA topoisomerase 3 (DNA to... 61 2e-08 1 15.8% 42:174 562:703 -----------------------------------------PKILSTPDMTALWYEQQLEIQNGNLSKDDFLNRVFDEVEEQIELIKNNALLDKNFNGIDKTYP--CKCGKGFLQKRHskTGKDFWGCSNWKncSEIYPdnIPKYFCPKCGSALNRWKNKKggYYWSCSgkGCQ------
195 UniRef50_A6DJX4 DNA topoisomerase n=2 Tax=B... 61 2e-08 1 29.8% 8:54 850:896 -------EEKTDVKCPKCDSPIVKKVGKRGPFYACSGFPKCKNLANSLDKFTEE------------------------------------------------------------------------------------------------------------------------------
196 UniRef50_Q1NX61 DNA topoisomerase I:Restric... 60 2e-08 1 21.1% 67:142 195:273 ------------------------------------------------------------------MGKPIDLVQGNQLVDLVRNVQGPQVATANTEGSQQATGRCPECSKNLVLrrGSRIGSRFWGCSGYPRCRYTQEYRE--------------------------------------
197 UniRef50_Q4SVN5 DNA topoisomerase (Fragment... 60 3e-08 1 18.3% 87:179 613:721 --------------------------------------------------------------------------------------QEITEEQQQDMEIPLPVRKCPHCGRDMVLKKKREGNGKYLTCVGYPACKSAVWFPDteSVCPTCQphMLKFKFRRGseFVGCIG-GCDETLRE-
198 UniRef50_A3WL27 Probable transmembrane prot... 60 3e-08 1 16.4% 67:139 205:280 ------------------------------------------------------------------KGKPIHIIDGETFHRFVRQREKAAVRFPPSPNTRPTTQVCPKCEGPMVKrrGPNRGESFWGCKRFPKCHGTRP-----------------------------------------
199 UniRef50_Q2B8U1 Putative uncharacterized pr... 60 3e-08 1 36.7% 1:49 1115:1163 MREVATLSGNILKVCPKCGKPLVERKSEYGVFYGCKGFPKCRYIESKKK-----------------------------------------------------------------------------------------------------------------------------------
200 UniRef50_D0D7V2 DNA topoisomerase n=1 Tax=C... 60 3e-08 1 23.7% 6:102 623:716 -----REDGSDPRICPKCggRLHLKTSRTGGFVGCGNYPECTYTRPI----AGEGADGEERLLGSHEGDEVWLKAGRFGPYVQRGEPTPENKKPPRASLPKK------------------------------------------------------------------------------
201 UniRef50_B8EMQ0 DNA topoisomerase n=153 Tax... 60 4e-08 1 30.2% 6:91 595:686 -----KEDGSDPRGCPSCggKLSLKLGKFGAFIGCSNYPECKFTRTlaEANGGERPGVKSLGVDPDSGEEITLRDGRFGVYVQQGEGEKPK-----------------------------------------------------------------------------------------
202 UniRef50_A2RKZ6 LtrE protein n=3 Tax=Lactoc... 59 5e-08 1 20.0% 9:88 2:81 --------ETTTEVCPRCHSRLTLREGKYGKFWGCKNFPKCVGTLPYDRYMSEQELADYFANRSKPQQIKIEKFVNIVSGYCICPHCN--------------------------------------------------------------------------------------------
203 UniRef50_B3V6G6 DNA topoisomerase I n=1 Tax... 59 6e-08 1 15.7% 71:178 84:198 ----------------------------------------------------------------------LLTSLKHIKENEQEIGKNIRHAISNSVNDENSLGKCPVCNSGNliIRSKKTKKRFVGCGNYNncRASAPIPqlKRICKECKWPMIYTRNKRFS-WKLCVNINCPTKEK--
204 UniRef50_Q18DJ2 DNA topoisomerase I n=2 Tax... 59 8e-08 1 17.6% 45:180 120:248 --------------------------------------------INSDIKYPLPKGATVQDECCESCGLPMIE-ATAGERFSICLDRECESLDDAVRERFDDEWTCPDCGAPMQIIRRS--GRLLAGCSGYPACefAIPTGVVVDVC-SCGLPIFETSRGQ-----QCLDGTCELLNKTD
205 UniRef50_Q4A5N2 DNA topoisomerase n=2 Tax=M... 59 8e-08 1 30.9% 1:55 558:613 MEKTRLEDNFLDEDCPDCSGKLLIrnRKKQKFIGCKSFPNCTYTRSYEDPDAKKR-----------------------------------------------------------------------------------------------------------------------------
206 UniRef50_B5EPF0 DNA topoisomerase type IA z... 59 8e-08 1 38.1% 6:47 693:739 -----SPTQPHAVTCPQCGSRMVRRTARRgpFWGCSRYPSCTGTRPI-------------------------------------------------------------------------------------------------------------------------------------
207 UniRef50_A8LLS2 Putative uncharacterized pr... 59 8e-08 1 17.0% 41:140 149:258 ----------------------------------------CWGLRALGKQIRRFQTPVLSEAEVDRHHDTLRRLDRGDEARDAHIAANRARhrPPETGAADTPCACPRCGADMVQRTARKTGTAFWGCRSYPKCRGTRPI----------------------------------------
208 UniRef50_Q3SMS7 DNA topoisomerase n=8 Tax=P... 59 8e-08 1 34.9% 13:98 572:654 ------------EACPKCAKPLFMQASKRGLFIGCSGYPECDYTRPL---HPATAEGDNILGKDPASGLDVKLLSGRFGPYVQIGDMPEDKKAPKPRR----------------------------------------------------------------------------------
209 UniRef50_B1M0P4 DNA topoisomerase n=14 Tax=... 58 9e-08 1 26.4% 92:144 590:641 -------------------------------------------------------------------------------------------HIFPDKGDGSNPRTCPTCGSGQLSLKLGKFG-AFIGCSNYPECKYTRQLSATG------------------------------------
210 UniRef50_A7IJK3 DNA topoisomerase type IA z... 58 1e-07 1 20.1% 4:137 50:151 ---EIEAEEGVLSPCPKCggTMKRYDGQYGPFEACSTHPRCDFKRNISVESSRAGAPSNR---------------------------------VRIARPMSVGDYCPTCGDGSMVVRSGGAYQPFLACSGYPSCKTT-------------------------------------------
211 UniRef50_C5DA42 NERD domain protein n=1 Tax... 58 1e-07 1 34.8% 2:47 216:261 -KQKQTEQHIQQNRCPKCGGVLIVRKGKYGTFKGCNNYPKCKFTQSI-------------------------------------------------------------------------------------------------------------------------------------
212 UniRef50_C3Z742 Putative uncharacterized pr... 58 1e-07 1 19.5% 45:177 240:385 --------------------------------------------RKDPKVVLAEQVQKYKQVFIEACAQALKLDEALGTYF--GEAQPFAEQDMNPVQVSPPVRPCPQCGESMVI-KTRKDGGLMLSCMGYPDCRAVAWFprDEAICTRCQPGPVHKIKFKFKryLGCIG-GCDETV---
213 UniRef50_Q9NG98 DNA topoisomerase 3-alpha n... 58 1e-07 1 16.4% 95:167 647:727 ----------------------------------------------------------------------------------------------PSHGIIQSIFQCPKCNEAPLALKPKKNQQGWygCNNFPDCKNAVWLPtlDECCPTCGDGYRMLKFRLSTPYYR-------------
214 UniRef50_C5V7F2 Restriction endonuclease n=... 58 1e-07 1 36.8% 9:46 280:317 --------EYTTPSCSSCGIKMVRRTGKRGDFWGCANFPKCRQMLN--------------------------------------------------------------------------------------------------------------------------------------
215 UniRef50_D1CHV6 DNA topoisomerase type IA z... 58 1e-07 1 30.4% 1:46 160:205 ISAAQVERPRAEHRCERCGGLMELRSSSRGQFWGCTNYPRCRHTLP--------------------------------------------------------------------------------------------------------------------------------------
216 UniRef50_A7JLN3 Predicted protein n=3 Tax=F... 58 1e-07 1 43.2% 3:46 209:257 --KSLKEKYKSEEICPKCSGLLVERTIKKGkfLGCSNFPKCRYTKS--------------------------------------------------------------------------------------------------------------------------------------
217 UniRef50_UPI0001C42CB2 DNA topoisomerase III n=1 T... 58 1e-07 1 23.8% 4:83 317:398 ---VERIKSESIGACLLCGSNVVLRKGKHGEFYGCSNYKdcTFNLPFKVLNKKLSKKQLMELLKNEKTDIIKGFKWKDKTFNA-------------------------------------------------------------------------------------------------
218 UniRef50_C7NA27 DNA topoisomerase n=20 Tax=... 58 1e-07 1 27.1% 1:48 696:743 LQEIDRKIIEEAGVCEFCGKPYEIKTGRFGKFLACTGYPECKTIKNIK------------------------------------------------------------------------------------------------------------------------------------
219 UniRef50_Q5UEY8 Putative uncharacterized pr... 58 1e-07 1 26.2% 3:82 145:229 --QSLRDRHSSTTICPRCGSNLVERTVKNgqFLGCEDYPKCRFTRDLPPVESGVRNGSSVGGFILKIILAFSGIAAIYLFFW--------------------------------------------------------------------------------------------------
220 UniRef50_Q3BT95 DNA topoisomerase n=14 Tax=... 58 1e-07 1 38.5% 8:59 611:662 -------KVPHGPACPQCGAPTHQRSGKSGPFWSCSRYPDCKGTLPVESGTSKRVASRS-------------------------------------------------------------------------------------------------------------------------
221 UniRef50_C0A759 DNA topoisomerase n=4 Tax=B... 58 2e-07 1 18.1% 13:139 638:764 ------------GPCPACHAPVM--RGRTG--YGCSQWrgCKFVLPGDYLGLTITPVLAREILIHKHtqPVVIKQSPCLAtkGALTHDVVQQVNKAGEGSDTLGRCPACGGDIV------AGVKAYGCSNWRncRFVVW-----------------------------------------
222 UniRef50_A6BK25 DNA topoisomerase n=12 Tax=... 58 2e-07 1 16.8% 74:180 617:717 -------------------------------------------------------------------------FIKDIESYTKELIQDIKTSDGTFRHDNLTNTKCPHCGKRMLSVKGKN--SRMLVCQD-RECGYRETIARtnARCPNCHKKMELIKKGDSETFV-CS---CGYKEKLE
223 UniRef50_B4S2M3 Putative transmembrane prot... 58 2e-07 1 19.2% 19:138 123:252 ------------------GIDLELRKGDERVIVQCKQWKAQKVGVSVVREMFGVLTASNANKVIIICSGKFTQQAIDFASDKPVVLIDGDELLSLIHDVQTEPktCPRCGSDLVERQAKraGNTFLGCSAFPKCRYTE------------------------------------------
224 UniRef50_C4V616 DNA topoisomerase n=1 Tax=S... 58 2e-07 1 26.7% 11:70 622:682 ----------EGIPCPACggVMLKRKGKHGDFWGCSAFPQCRMTADDAGGKPNFAGRRVPRGSADGMGAH--------------------------------------------------------------------------------------------------------------
225 UniRef50_C9LWM4 DNA topoisomerase n=1 Tax=S... 58 2e-07 1 25.3% 98:180 613:702 -------------------------------------------------------------------------------------------------PKDKKRTPCPICREGILLRKYSQKSkyFHMCSNE-KckMFYPdePVVAFCPEC-ETVLAKLNGKNGAFWLCN--HCKKTFDDK
226 UniRef50_A5N5N2 DNA topoisomerase n=4 Tax=C... 58 2e-07 1 14.0% 1:136 598:728 IDRIESKKYESMGVCPICGKGNIM-ANKFG--YGCSRWRecKFFIGKQIAGKNISESMAKKLIKNKKTNVIKGFKSKnkSFDAVLTIKDENVAFDFSSESKGLGTCPVCGKGNVI--ANKSG---YGCDKWKecKF--------------------------------------------
227 UniRef50_UPI00017C3C60 PREDICTED: hypothetical pro... 58 2e-07 1 25.7% 68:141 745:817 -------------------------------------------------------------------GSIFLEEITKDQSFKEFIHIPQDEYKQLNSNIPPEWL-CPKCGQGRLRKITNGPYGAFLGCSRYPNCKYTKNLK---------------------------------------
228 UniRef50_C5U8C5 DNA topoisomerase (Fragment... 58 2e-07 1 33.3% 1:48 298:344 IGKNLTNKEV-VGTCPRCGSPLVVKEGKYGKFIGCTNFPKCKFTKSLE------------------------------------------------------------------------------------------------------------------------------------
229 UniRef50_A5INJ9 Adenine-specific DNA methyl... 57 2e-07 1 18.1% 39:176 164:307 --------------------------------------PHCLEEYAKINSREPEDVLKEVVEKLKVANDPKEVYGQYWFEDGSKIGFKKNIFADTMYYFWIKEVPCLACGTKIPLFrkTRDGKGYHVIC--PECefVVNNYEKDTECPRCGKKFNPDKDGneGKYYICTNPNCGQK----
230 UniRef50_A5N8B3 Transposase n=4 Tax=Clostri... 57 2e-07 1 18.0% 80:179 70:171 -------------------------------------------------------------------------------YYKHKYNKLIKPVQRRNGKSIPEDIVCPRCGAPNHYIYDNNGNRGQFQcqNFNESNHA--DKSMVFLCPYCGHTLSPKKDRKHFRIHKCVNPECSYYQSN-
231 UniRef50_A1SXM8 DNA-binding NERD domain-con... 57 3e-07 1 33.3% 1:42 218:264 VEAKQAPKVIEEKTCPKCGTLMILREAKKGkfWGCSNFPQCR------------------------------------------------------------------------------------------------------------------------------------------
232 UniRef50_B9XT21 Restriction endonuclease n=... 57 3e-07 1 20.3% 68:141 187:263 -------------------------------------------------------------------KKHNITLLGEPELMALCENLNWKQNPEILSLLNDTRKLCPKCESEMVLrrGPNRGNQFWGCSTYPKCHYILNIS---------------------------------------
233 UniRef50_A1TJM5 DNA topoisomerase n=55 Tax=... 57 3e-07 1 29.5% 2:62 614:674 -EATLAIRVPAGPPCPLCGAATRKRTGKTGAFWSCSRYPDCKGTVAIDSAEAGRRNGPRKPR----------------------------------------------------------------------------------------------------------------------
234 UniRef50_Q13472 DNA topoisomerase 3-alpha n... 57 3e-07 1 14.0% 2:180 645:850 -EDIYPAMPEPIRKCPQCNKDMVLKTKKNGGFysCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKfpPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQHpdSRQTGSSKALAQTLptCNCglTVRKEgrGRQFFKCNGGSCNFFLWAD
235 UniRef50_A3DB61 DNA topoisomerase n=1 Tax=S... 57 3e-07 1 19.3% 44:131 594:682 -------------------------------------------MFKQGQYTLKLPKVLAVTLPCPVCQKSMKQLSGKNGKFWVCEDKEQCGLLLNDERGKLPKTTPCTCKKGVLVRKKAkkGKFWWGCSAY-------------------------------------------------
236 UniRef50_B9KGJ1 DNA topoisomerase III TraE ... 57 3e-07 1 14.2% 20:146 551:674 -------------------KKQVVKSTKKGRLLI-SLAPE---TLKYPDMTALWFEQQKMIEQGTIKKEDFLQNILKEVNSEILKIKENGSMNQFSQLSKEKQYSCPECKNGYLIRRKNTKGTYWWGCSEYKncKFMCFDEKNKPK----------------------------------
237 UniRef50_Q9X3X7 DNA topoisomerase 1 n=7 Tax... 57 3e-07 1 21.5% 74:138 565:628 -------------------------------------------------------------------------MEQQPSAITAELDKFLEPWLFPDKGDGHDPRECPSCHTGRLALKGGRFG-AFIACSNYPECKYTR------------------------------------------
238 UniRef50_D0GKB0 DNA topoisomerase n=1 Tax=L... 57 3e-07 1 28.3% 3:48 711:756 --NEDKKIIEEAGVCEKCGRPFEIKMGRFGKFLACTGYPECKNIKAIP------------------------------------------------------------------------------------------------------------------------------------
239 UniRef50_Q58078 Uncharacterized protein MJ0... 57 3e-07 1 39.1% 5:50 256:301 ----DIMSKIDDNTCPWCGAKLRVVRTKKGEFLGCTNYPNCLYRRFPKKN----------------------------------------------------------------------------------------------------------------------------------
240 UniRef50_B0G7K1 Putative uncharacterized pr... 57 3e-07 1 23.0% 1:61 298:365 LEEVQKEIPATTGkcPVCGGELVLRTARRgqFYGCSSFPRCRYILNIAENLEKSDTSHSKK-----------------------------------------------------------------------------------------------------------------------
241 UniRef50_C0ZFC8 Putative uncharacterized pr... 57 3e-07 1 31.8% 2:45 192:235 -KKVIAQFQSKTHICDKCRSQMVLRKGAKGEFYGCKGYPKCRNIK---------------------------------------------------------------------------------------------------------------------------------------
242 UniRef50_C1LZJ7 Prokaryotic DNA topoisomera... 57 3e-07 1 20.9% 15:143 669:848 --------------CPTCHSGLVLRQKRsgWFLSCSGYPNCRYAIWFPDSVIHVRVLSETNetCNRCADFilRFRRNFYLPNGYIQDDDTKESVDNAEAGDSDNILCNCGHSAIQLTVKkqGRLFYRCPGlnSCDFFLWKSQT-------------------------------------
243 UniRef50_A3EW25 DNA topoisomerase n=3 Tax=L... 57 3e-07 1 36.5% 11:62 614:665 ----------EGKICSECGGVLRRLEGKFGPFLGCSGYPACRHLEKLPGAVSTNKRSPSRGK----------------------------------------------------------------------------------------------------------------------
244 UniRef50_C7GFC6 DNA polymerase III, alpha c... 57 4e-07 1 34.1% 6:46 185:225 -----SAKQTEEKICPRCGLALKKRNGRFGGFWGCTGFPDCRYTKN--------------------------------------------------------------------------------------------------------------------------------------
245 UniRef50_UPI0001C3586C hypothetical protein ChatD1... 57 4e-07 1 18.1% 93:175 8:92 --------------------------------------------------------------------------------------------QRRNGKSVPEDTVCPLCGAPHHYLYDNNGGNGQYQccGQTFVTGEVVTSPVRFVCPYCGHTLVPKKDRRFFRIHKCVNPKCSF-----
246 UniRef50_A5FDL0 NERD domain protein n=1 Tax... 57 4e-07 1 41.5% 7:47 218:258 ------KKTIQEIKCPKCGNKMIQRQGKFGIFLGCKSYPKCNYTQQE-------------------------------------------------------------------------------------------------------------------------------------
247 UniRef50_A3CKM8 Putative uncharacterized pr... 56 5e-07 1 20.2% 70:153 220:301 ---------------------------------------------------------------------DLYRMLLPLTKRKQVIKERHINSIAQNKQRREAEKICPRCQHRLVLrkGSRAGQQFWGCSNFPRCRFTQKYQE-----PVCSPP---------------------------
248 UniRef50_A4ALZ1 Helicase IV n=1 Tax=Flavoba... 56 5e-07 1 17.0% 1:88 826:914 IEEIEPFPPITSLKCEWcnGKLVERNGRFGYFYACNNSHYCNYTRKIEAIDLKNVALEFSEKKDFESAIKYYLKSLEIGNDNGNTHFE--------------------------------------------------------------------------------------------
249 UniRef50_C7J0A2 DNA topoisomerase n=2 Tax=M... 56 5e-07 1 13.5% 102:175 639:719 -----------------------------------------------------------------------------------------------------TVRPCAACNESEMFLKQRPTGEFMVGCRGFPQCRNVVWLPrtDQVCPTCAPGPVYKIQFKFRRRDIPPNFDVDH-----
250 UniRef50_B6KRJ5 DNA topoisomerase n=3 Tax=T... 56 5e-07 1 17.2% 48:146 1715:1812 -----------------------------------------------DSMPTQASEETDEKETEATAGETNAETGRGAEKARSRATEASAKRGTDGVGSSFTPPLCPSCGEGVLKLRIHSRG-IFVGCSAYPRCTYTQSVPPPQKR----------------------------------
251 UniRef50_C6WSV7 DNA topoisomerase n=4 Tax=P... 56 6e-07 1 28.1% 9:97 581:671 --------ELIDEACPKCGKPLQKQLSRFGSFIGCTGypKCDYKRSIDGTANAGTDPVSIG-VDAATSKEIYLMNGPYGPYLQVGMAVEGEKKKPKR-----------------------------------------------------------------------------------
252 UniRef50_C0FNH3 Putative uncharacterized pr... 56 6e-07 1 31.7% 6:46 187:227 -----AKKQSKEKICPECGLPMKKRNGRFGEFWGCIGYPDCRHTEN--------------------------------------------------------------------------------------------------------------------------------------
253 UniRef50_C5A9D2 DNA topoisomerase n=1 Tax=B... 56 6e-07 1 28.3% 80:139 657:720 -------------------------------------------------------------------------------PPDAMPARKPYTGSSTPRPAPDGAKKCPKCKKGYLVPRtpKAGQTFHGCNNYPECKHSVW-----------------------------------------
254 UniRef50_C1MEL7 DNA restriction n=1 Tax=Cit... 56 6e-07 1 28.3% 2:47 309:354 -GENEINDPNAIPNCPRCHSKMVRRMSNGTYFYGCSVYPICKGTRNY-------------------------------------------------------------------------------------------------------------------------------------
255 UniRef50_C0A3Z7 DNA topoisomerase type IA z... 56 6e-07 1 22.7% 72:146 180:257 -----------------------------------------------------------------------MEKQGEIFATRGGFREKLTAIRVDARAQQEAAPNCPECSAPMKRRKAknAGKEFWGCTAYPQCKGIREIPPPANP----------------------------------
256 UniRef50_B5EU43 Topoisomerase-associated Zn... 56 7e-07 1 17.4% 24:138 90:218 -----------------------KISAKHFDFVLCNQDdiCAIELDDSSHNNAKRkdQFLESACESAHFPLIRIPAKQAyfSLQSVLSNPEPEMPSFDLDSTDKQCPKCSSNMVLKVAKKggNEFWGCSSFPACRHIE------------------------------------------
257 UniRef50_C1E9E3 DNA topoisomerase n=1 Tax=M... 56 7e-07 1 23.2% 7:101 813:911 ------EELSSTRRCPGCggRLGLKLSRTGGFIGCSNYPSCGHTRQLVNDGDGAvnFPIELGTDPESGGDVAIQNGPYGPYIELQMPSSPDDSKKTKPQRF-------------------------------------------------------------------------------
258 UniRef50_Q8L288 DNA restriction n=1 Tax=Pro... 55 8e-07 1 38.7% 15:45 325:355 --------------CSICGGTMLLRTGNKKTFWGCSNFPECRNTR---------------------------------------------------------------------------------------------------------------------------------------
259 UniRef50_D0UIR3 TraE-like protein n=1 Tax=A... 55 8e-07 1 19.2% 1:125 609:725 IKQAelKVELKGEPC-ECggVLILRKTDKGTFFSCSSYPECKVIKPALNNAPMPN--------CPCCNGNL-KGNSAVIECEKCGLKIWRKLMNKTLTDSQLLALITKGKTPLIKGFTGKSGKEF-------------------------------------------------------
260 UniRef50_A8S9Z2 Putative uncharacterized pr... 55 8e-07 1 27.7% 1:47 217:273 IEEVRAKHYPIIKpcPQCGGRLVPRVARQGsfWGCSNYPKCHFIYNK-------------------------------------------------------------------------------------------------------------------------------------
261 UniRef50_Q04TE1 DNA topoisomerase n=4 Tax=L... 55 9e-07 1 23.3% 85:144 554:613 ------------------------------------------------------------------------------------SVFRKEWAEIREKKKETSWGICPLCRDGSLQKKKTSRKKEFYQCSRFPDCEYVNYELPKP------------------------------------
262 UniRef50_C4ZL79 Restriction endonuclease n=... 55 9e-07 1 34.2% 11:48 276:313 ----------TTPTCPSCGVKMAARDGTHGRFWGCVRFPKCRATLQMR------------------------------------------------------------------------------------------------------------------------------------
263 UniRef50_B0RMG6 Putative uncharacterized pr... 55 1e-06 1 16.7% 42:137 182:277 -----------------------------------------TYTKDAERFAEGKPIELIGGEQLLDMIRAVQQQATAQSTSAPVRIDPVFASTESTASATIATPSCPRCGSKLVQRRNRRTRENFLGCSQFPKCRGT-------------------------------------------
264 UniRef50_C6N6E9 DNA topoisomerase n=2 Tax=L... 55 1e-06 1 38.5% 10:48 617:655 ---------NSTYSCPDCQKTLMKRQGSKGAWWGCSGYPQCKTRFSDK------------------------------------------------------------------------------------------------------------------------------------
265 UniRef50_Q4L0S6 TraE-like protein n=3 Tax=G... 55 1e-06 1 25.4% 107:173 628:690 ----------------------------------------------------------------------------------------------------------CSCGQGVLVLKKFKD-SEFFACTAYPTCKITKPALnpAPNCPCCNSHVRVNEKG-----VFCSNEGC-------
266 UniRef50_C5SZL6 Restriction endonuclease n=... 55 1e-06 1 33.3% 4:45 250:296 ---AIAKAETAAPDCPRCGASMQLRTARQGafWGCSTYPKCRGTR---------------------------------------------------------------------------------------------------------------------------------------
267 UniRef50_Q1RIM1 DNA topoisomerase 1 n=35 Ta... 55 1e-06 1 23.7% 8:100 593:694 -------ENKDSKVCPSCkgELSLKLGKFGAFLACSNYPECNFRknEADGEAKDIVNENKVLGKDKEGIEIYLKKGPYGPYIQYGEQVDSKIKPKRSPLP--------------------------------------------------------------------------------
268 UniRef50_A4RYV6 DNA topoisomerase (Fragment... 55 1e-06 1 41.9% 102:144 679:720 -----------------------------------------------------------------------------------------------------EARRCPSCKIGRLGLKPSKAGG-FIGCSRYPECGFTHPLHPIR------------------------------------
269 UniRef50_Q9ZLV6 Cag island protein n=3 Tax=... 55 1e-06 1 18.2% 2:166 14:194 -SKFNIKRVRGYLICLVCNTPKMIQRGLNgsFYGCSDY-----VNKGDCKGVLREINGSMKMVCLHCENtmEKVESGRGGAYACKNCNRKFYFIDLAKQNERKKDLEKEKKELlvKANIKENSFFLGCKNYPKCEWTASMDSQDLKCPKCNRLMKRKKNFKNNEFF--------------
270 UniRef50_B7IYV7 DNA topoisomerase n=7 Tax=B... 55 1e-06 1 13.3% 2:136 495:634 -EIAQLEEMKKIGECPNCGSDIVE----HEKFYGCKGykQCNFSIQKVIAKKKISPAQVKKLLKDKKTDVIKGFKSSKSERTFETFLYYDSEKknKPSSKDTGFKCPLCKDNLVEHQK------FIGCSGFKncEF--------------------------------------------
271 UniRef50_B9LTA7 DNA topoisomerase I n=1 Tax... 55 1e-06 1 19.6% 13:175 101:243 ------------GTCPEDGGVLVRSRGD----VVC---LDCETRWGLP------AGASVTDGVCEDCELP-KIRIERGEPFHLCLDPACDPMEAAVSDRFDRVWGCPDCEGDLTV--QSAPGRVYLACENRPGctFSIPSGVVVDEC-DCGLPVFETAAGR-----GCLDGSCEY-----
272 UniRef50_B9TJX8 Putative uncharacterized pr... 55 1e-06 1 27.7% 15:97 2:86 --------------CPKCGRQLQKQLSRYGSFIGCTGypKCDYKRNLDGEANAASEPVVIGQD-VDTQKDIYLMNGPYGPYLQVGQPVEGDKKKPKR-----------------------------------------------------------------------------------
273 UniRef50_UPI00016C5644 hypothetical protein GobsU_... 55 2e-06 1 21.4% 61:177 789:915 ------------------------------------------------------------GYVCVPLGGRWVAVNSPNVTRVLWRIGFSHLADDEVDPNQARRFYCPECPNGDLVLRQSRGEGWFLVCVnvRECSHRKRLSLEDarCPA--GHPLTARSSGHGFFLGCEnpRCDFAQ---
274 UniRef50_A6AAL5 Restriction endonuclease fa... 54 2e-06 1 24.5% 90:138 218:269 -----------------------------------------------------------------------------------------NKPDIDEPTPDPHSKVCPNCQSNLVIrkGRNAGKSFYGCSAYPKCRYTC------------------------------------------
275 UniRef50_C0A7I9 DNA topoisomerase type IA z... 54 2e-06 1 27.9% 6:48 199:246 -----RAAKENAPLCPECGKPMKRRKARTGpfWGCTGFPDCKTTREIP------------------------------------------------------------------------------------------------------------------------------------
276 UniRef50_A6URC3 DNA topoisomerase type IA z... 54 2e-06 1 37.5% 4:51 262:309 ---EELKKHNDENTCPWCSEKLKLIRTKKGEFLGCSSYPTCLYRRFLNKKQ---------------------------------------------------------------------------------------------------------------------------------
277 UniRef50_Q4AA55 DNA topoisomerase n=5 Tax=M... 54 2e-06 1 11.6% 38:166 514:633 -------------------------------------YENLKIISPEIIDAKFTAQVEEELDLIAQGKQDYKKYLDSMWSKIENTIEKAVEVEKVIMEARTTGEKCTECDADLVYRYNRKTNQRFIGCSSFPNCRFIKVDE---------NAKKVYRFRKRNTKIL--------------
278 UniRef50_C8VYF5 DNA topoisomerase n=2 Tax=F... 54 2e-06 1 19.8% 98:178 603:679 -------------------------------------------------------------------------------------------------PDNVTGNKCPKCRKFLLSVKTKRGSN--LVCPD-RSCGHRQVEKEtnRPCPQCKKRRMEIREGKGGKIIVCT--HCRYQEK--
279 UniRef50_A1U4Z3 NERD domain protein n=4 Tax... 54 3e-06 1 16.8% 32:138 148:259 -------------------------------FVGDSTfpMPDNVTYGGGYICFIKSRTEEVLAEAEVQDIVSKIETGRLAATFRNHRQHVAHVKDIVEQKASEPKCPKCQGAMvvRRGANVGKEFWGCKAFPKCRGIV------------------------------------------
280 UniRef50_C2U731 5-methylcytosine-specific r... 54 3e-06 1 20.9% 100:142 172:214 ---------------------------------------------------------------------------------------------------KPAERKCPTCKHDLVIRNSNKTGNKFFGCSQYPTCTHTEPINT--------------------------------------
281 UniRef50_A1VWJ5 DNA topoisomerase, type IA,... 54 3e-06 1 17.7% 77:138 87:151 ----------------------------------------------------------------------------QQRKRSSSPQPLSGFSAEPHQANAGISPHCPVCSSSMVRrrGANAGKSFWGCSQYPRCKGTQ------------------------------------------
282 UniRef50_B0MQN7 DNA topoisomerase n=1 Tax=E... 53 3e-06 1 13.6% 11:150 485:614 ----------NTLICPLCGKPVIKKKVG----WCCTGYSkcKFYIANEICGKKISDVIAKELMLKRATSIIKGFTSQSGK--SFDAKLIIKDDNTIGFEFPERLRCPICGKEMV--KSSKG----WVCTGYKncNFFI----AGTICGKC------------------------------
283 UniRef50_Q7Q111 DNA topoisomerase n=3 Tax=E... 53 3e-06 1 16.0% 85:165 639:726 ------------------------------------------------------------------------------------PDAGASAATATGSAPMREVCKCPKCGHKMCLRTKRDSSGYYLGCVAFPECRNNIwiNVLDDTCARCGSKKMTVKFRSVRFY---------------
284 UniRef50_A2UW18 DNA topoisomerase, type IA,... 53 4e-06 1 20.8% 94:141 655:703 ---------------------------------------------------------------------------------------------KPKMASTATEFQCKQCGEKLIKREskKKGEFWYGCSGYPKCKATYQDK---------------------------------------
285 UniRef50_C6V581 DNA topoisomerase n=2 Tax=N... 53 4e-06 1 18.2% 2:100 588:687 -QKLVSAEVKVGDKCPKCegYMHLSVSRYGVFLGCTNYPVCRFIVNSYSTDDDTEYPKQIAQDISLHKGPYGIYLKYKGKNSSIPKDVDPVSIDEEFAHK--------------------------------------------------------------------------------
286 UniRef50_B7U5A8 DNA topoisomerase n=2 Tax=B... 53 4e-06 1 13.1% 1:145 581:726 IKSLESETEKEVinCPNCGREMYE----NQKAYSCSGYQdcKTVLwlEKLGKKSIGKAEAKKLLAGESIKVKLKSKAGNPYEKRVIFNKEKYWVEFCEEEDPTEkcPNCGREMYENQKA------YSCSGYQdcKTALWKNGLEK-----------------------------------
287 UniRef50_A8U720 DNA topoisomerase n=3 Tax=L... 53 4e-06 1 17.3% 1:104 613:713 MNQTISQTKQTIGTCPACGQSIIDK----GKFYGCSGYSncTFTLPKRYVGKTLSEATIKKLLKTKETSLLKGFKKKTGETFSAALIVNEEHKVMFKPYKKTDK----------------------------------------------------------------------------
288 UniRef50_C4ZF87 DNA topoisomerase I n=1 Tax... 53 4e-06 1 31.2% 2:49 413:460 -EKARQKQRYDPNICPECGGRLRLIQGPFGKFMGCENYPTCKFNRRVRK-----------------------------------------------------------------------------------------------------------------------------------
289 UniRef50_A9V1D2 DNA topoisomerase n=1 Tax=M... 53 4e-06 1 18.7% 72:162 598:694 -----------------------------------------------------------------------VVCREMDRFDNAFVHQFGEASGAPPMVSGEAWRTCPECKKAAQAFKTTKDKKWLLSCRGYPKCRASQwiSVLDRHCTRCHERLVRIEFRAG------------------
290 UniRef50_B9M296 DNA topoisomerase type IA z... 53 4e-06 1 29.8% 2:48 120:171 -ERASVQAEVAVPVCPKCEAIMVKRQAKNGafWACSMYPGCRHIVAID------------------------------------------------------------------------------------------------------------------------------------
291 UniRef50_UPI000179C790 UPI000179C790 related clust... 53 4e-06 1 24.6% 68:136 643:710 -------------------------------------------------------------------GSIFLEEITKDQSFKEFIHIPQDEYKQLNSNIPPEWL-CPKCGQGRLRKITNGPYGAFLGCSRYPNCKY--------------------------------------------
292 UniRef50_Q2SR72 DNA topoisomerase n=4 Tax=M... 53 4e-06 1 20.9% 3:69 571:639 --KKEIGEAKTEAICPRCGANLVYIKSRFNRGRGCSNftKCGYRKYEQPDGTWKEYIKEEKNIDDNTKK---------------------------------------------------------------------------------------------------------------
293 UniRef50_A3JU58 DNA topoisomerase I n=1 Tax... 53 4e-06 1 17.4% 96:141 135:180 -----------------------------------------------------------------------------------------------KPASSMAQTPCPKCGGEMVKRVNRKTGNAFWGCAKFPKCRGTQKVA---------------------------------------
294 UniRef50_B4RLM8 TopB n=9 Tax=Neisseria RepI... 53 5e-06 1 28.6% 93:141 629:679 --------------------------------------------------------------------------------------------TKKQAVARNEDDVCPTCKEGRLRQRGFKEnkRYWGCSRFPECKHFEWVK---------------------------------------
295 UniRef50_A4JFS2 DNA topoisomerase III n=4 T... 53 5e-06 1 32.1% 92:144 701:757 -------------------------------------------------------------------------------------------HESSKTAPSAAVKACPECKTGKMVVRQAraGKPFLGCTNYPRCKHAERMPEKE------------------------------------
296 UniRef50_Q1Q969 Replication restart DNA hel... 53 5e-06 1 23.2% 106:161 493:548 ---------------------------------------------------------------------------------------------------------CPRCDAHLTVHYNNQAQRSNYSSNSYLKCHHCDWQAYIPTVCPDCGSQNLDAKGMG-------------------
297 UniRef50_A9A650 DNA topoisomerase type IA z... 53 5e-06 1 19.4% 81:178 43:149 --------------------------------------------------------------------------------YLSWSSKDKKYMILGTNSPKNGLVQCPECKVGELMVIRSRtrKRFMGCSnyGGCKASSPLLqtKSPCEVCKWPMVIFRYSRKQQwkQCSNFNCKSRIK--
298 UniRef50_UPI00019260D5 PREDICTED: similar to topoi... 53 6e-06 1 23.5% 13:80 148:216 ------------RKCPKCGNNMTLRKTKEgfFLGCMGYPNCRNSLFFPKFLLNAVRSDTTCLHCKPHPVHKIEFHFKRGS----------------------------------------------------------------------------------------------------
299 UniRef50_A1A2S5 Putative helicase IV n=2 Ta... 53 6e-06 1 15.1% 49:141 598:690 ------------------------------------------------ERMPHAEERRLFYVAMTRCKKKLF-FVVDQSRPSRFMYELHDKICPNIFRGVKLPPQCPNCGEALRLRHTGSdsRTFYGCTGFPNCRFTQQCK---------------------------------------
300 UniRef50_Q21XF5 Restriction endonuclease n=... 52 7e-06 1 24.3% 103:139 266:302 ------------------------------------------------------------------------------------------------------RPTCASCGIKLVERTPAKGGPAFWGCSNYPRCKSRLP-----------------------------------------
301 UniRef50_B9X9Z1 Restriction endonuclease n=... 52 7e-06 1 25.0% 99:138 238:280 --------------------------------------------------------------------------------------------------FNDTRKFCPKCEAEMVLrkGCNTGGTFWGCSQFPRCRYIL------------------------------------------
302 UniRef50_B5JHP8 DNA topoisomerase n=2 Tax=B... 52 7e-06 1 14.0% 4:160 595:750 ---EKTVDLKNLGPCPKCSAPVM--RGNTG--YGCTRWRecKFVVKDGVFGITFQPPLMRELLFNgePQPISDKGKKLLGFVVLGKQGALKYesQETHGQAKFGDCPLCKSAIVEGEKG------YGCCNWKncKFIIWKQVAQRPISEEEARFLLEKGE--------------------
303 UniRef50_B0P9H6 Putative uncharacterized pr... 52 7e-06 1 31.6% 11:48 256:298 ----------TVPLCPKCNVPMVRRTAKKgeFFGCPNFPKCRQIINID------------------------------------------------------------------------------------------------------------------------------------
304 UniRef50_Q2FA01 Putative uncharacterized pr... 52 7e-06 1 34.8% 3:48 187:237 --KEVVTSKASSNQCPRCGSEMVLRETKRGefWGCSTFPKCRAVKQFN------------------------------------------------------------------------------------------------------------------------------------
305 UniRef50_A5CF60 DNA topoisomerase n=2 Tax=O... 52 8e-06 1 20.0% 9:108 592:697 --------ETDHKLCTLCkgKLSLKLSKYGAFLACNNYPSCNFTRNinNDNLPKGKNNKAIGYSDDMQKTIYLKEGPFGWYIQAGEDSTNKNDKPKRVPISVISSSPQ------------------------------------------------------------------------
306 UniRef50_Q3IU69 Homolog to DNA topoisomeras... 52 8e-06 1 22.2% 17:169 100:235 ----------------RCGGDLV----RSGGGVSC---LDCGERFGLPSGATTTGDD-------CSCGLP-TVRVDRGEPFELCLDPDCGSLLEAVRAAFEGEWACPECGSDLDIIRR---GGLLAGCEQYPDCefSIPDGVVDGRC-GCGLPVFETATGRRCLDTDCS-----------
307 UniRef50_Q5NWJ2 DNA topoisomerase n=31 Tax=... 52 8e-06 1 15.9% 102:145 632:675 -----------------------------------------------------------------------------------------------------TLYKCMACGQGLIRRPTKKADVFWWACSNFPTCKQSYPESKNPK-----------------------------------
308 UniRef50_C6I107 DNA topoisomerase n=1 Tax=L... 52 8e-06 1 28.8% 97:169 602:696 ------------------------------------------------------------------------------------------------DPSSPAKIACPVCGGQALVTRrnKKGVFFWTCsgTPGAPFSepLNSDGPPCPTCRKPLSAETTSKGTAYFRCA-----------
309 UniRef50_B7R6E2 Topoisomerase DNA-binding C... 52 9e-06 1 25.7% 1:70 4:78 IRRNEGGKNMKKVKCKQCDGYYVLKSGKFGEFVGCSNFPDCKSTLKIYEWAFEYIKeyGWDRICWKCGKT--------------------------------------------------------------------------------------------------------------
310 UniRef50_D2R6E6 DNA topoisomerase type IA z... 52 9e-06 1 54.5% 15:47 218:255 --------------CPKCGAAMVVRTAKNgkFLGCSNYPKCQTMAKL-------------------------------------------------------------------------------------------------------------------------------------
311 UniRef50_A1U7T2 DNA topoisomerase I n=2 Tax... 52 1e-05 1 15.6% 2:180 551:717 -ERLEAESLALKGRCPGCDQPIIQKH-RKGSGRG----------------------------KGRSQGSRAFWVHIDDAHAAACVQYLNDEHDAPVLPPPEVTSPCPQCQA-TLIRRYSKTGSryWacGvfPDVDgvIPEPIPETKCVDCGGIMKKRKNSKTqwVHVAKKPSCGNLFIDD
312 UniRef50_UPI0001C3753D NERD domain protein n=1 Tax... 52 1e-05 1 37.0% 2:47 245:295 -KEHIKRIEQRKRICPNCGAKLIIRTAKRgkFYGCSNYPNCKYTKSI-------------------------------------------------------------------------------------------------------------------------------------
313 UniRef50_Q3BZV2 DNA topoisomerase n=1 Tax=X... 52 1e-05 1 33.3% 11:49 686:725 ----------SGAPCEKckGTMQLRNSSRGPFYGCSNFPVCKHTAPADS-----------------------------------------------------------------------------------------------------------------------------------
314 UniRef50_Q3JF73 Restriction endonuclease n=... 52 1e-05 1 16.9% 83:141 210:271 ----------------------------------------------------------------------------------QKHSKTDPGIVPKRAQSTQVDPNCPLCGKSMVLRKARkaGKKFWGCIAFPQCRGVRNCP---------------------------------------
315 UniRef50_Q1Q9M9 DNA topoisomerase I n=2 Tax... 52 1e-05 1 18.2% 65:141 259:338 ----------------------------------------------------------------HDITDKVFLTPFEVIETEPQVHYPATLVAIDNIANFIQAPTCPRCNSEMVKRVAKKggQTFFGCSQFPKCRGVVNTN---------------------------------------
316 UniRef50_B3T7R7 Putative Topoisomerase DNA ... 52 1e-05 1 18.8% 77:177 51:160 ----------------------------------------------------------------------------DSNGYLSYSAKKKKYIILGTNSPKSGLVECPQCKIGQLMIIRSptKKRFIGCSNYNncKASSPLLqtKTKCELCKWPIVIFRYNRKQKwrQCSNFRCKSRK---
317 UniRef50_C5UQ84 Topoisomerase DNA-binding C... 52 1e-05 1 31.8% 2:45 387:430 -EDLELKDYKKHLECPFCKGKLNQKYGKYGSFVSCSNYPECKFSF---------------------------------------------------------------------------------------------------------------------------------------
318 UniRef50_Q2B124 DNA topoisomerase III n=1 T... 51 1e-05 1 18.4% 2:88 277:357 -DKSYRAHNLTGSKCPECGSFLKERNTKDGKVLVCSDM-ECSYRKRKDPKL-----SNRRCPQCHKKNGDPQRQGRHLLPVPPVQCCR--------------------------------------------------------------------------------------------
319 UniRef50_C6NY48 DNA topoisomerase n=1 Tax=A... 51 1e-05 1 20.7% 14:124 618:737 -------------PCPICGGDAVVrkNRKVFFWSCSNRdqDDNGKPDKPFAERKEDSGPPGPECPHCAGTATRTKTTskTYYRCPSCQAAFWPDREDPQRLGAPWLPAESGG---RRGSSTKSY--------------------------------------------------------
320 UniRef50_Q3BM55 Putative uncharacterized pr... 51 2e-05 1 16.7% 42:137 75:170 -----------------------------------------TYTKDAERFAEGKPIELIGGEQLLDMIQAVQQQATAQPTAISARIEPVFGSADSTASANIATPSCPRCGSALVQRRNRRSGENFLGCSHFPRCRGI-------------------------------------------
321 UniRef50_B5RXB6 Zn-finger domain associated... 51 2e-05 1 37.5% 8:47 237:281 -------PSTERPHCPRCGNVMVRRTVKQGafWGCVTYPECRGTRGL-------------------------------------------------------------------------------------------------------------------------------------
322 UniRef50_A8K398 cDNA FLJ44921 fis, clone BR... 51 2e-05 1 19.0% 2:80 97:176 -EDIYPAMPEPIRKCPQCNKDMVLKTKKNGGFysCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKFKRGS----------------------------------------------------------------------------------------------------
323 UniRef50_C3SA84 DNA topoisomerase n=1 Tax=B... 51 2e-05 1 25.8% 96:157 669:735 -----------------------------------------------------------------------------------------------FPDLDDASRICPSCSEGTLRFKVSRFggYFIGCDRHPKCKYisDEDDENEACEETKWNFEPR-----------------------
324 UniRef50_A0LD91 DNA topoisomerase, type IA,... 51 2e-05 1 22.7% 99:142 203:249 --------------------------------------------------------------------------------------------------RQVDSPHCDKCGAQMQRKKVVkaGKRFWVCSNYPECRTMVPVSS--------------------------------------
325 UniRef50_A0KM30 Topoisomerase DNA binding C... 51 2e-05 1 47.1% 13:46 234:272 ------------PHCPRCDAPLVEREAKKGpfLACSRFPECRYAAP--------------------------------------------------------------------------------------------------------------------------------------
326 UniRef50_B5ECJ0 NERD domain protein n=1 Tax... 51 2e-05 1 36.4% 6:49 182:230 -----KERFNSTTICPKCSKELKLRTVKSGefYGCSGFPKCRYTKPVDD-----------------------------------------------------------------------------------------------------------------------------------
327 UniRef50_A8II62 DNA topoisomerase (Fragment... 51 2e-05 1 43.6% 9:47 620:663 --------QRDPRRCPKCggRLVLKPSRYGGFIGCSNFaqCDFARPL-------------------------------------------------------------------------------------------------------------------------------------
328 UniRef50_A5FHK0 DNA topoisomerase III n=25 ... 51 2e-05 1 24.6% 13:146 612:749 ------------ETCPKCQKGNFIK-GKSA--FGCSEYKscDFVLPYGFHDKKITESQYLRLVQKGSTVNIKGFKTDAGTVEGLIRFEENYKLKLEPKKTYIKKtcPKCKKGNILK-----GKTAYGCSEYKscDFKVTFDEVRAK----------------------------------
329 UniRef50_Q3A7U2 Topoisomerase-associated Zn... 51 2e-05 1 17.4% 93:138 204:252 --------------------------------------------------------------------------------------------IPPDPVSGQVVPFCTVCNSPMVKRQAKkaGKYFWACSAFPKCRNIQ------------------------------------------
330 UniRef50_A7VTK8 Putative uncharacterized pr... 51 2e-05 1 31.1% 3:47 934:978 --KKIKVADDPAMRCEFCKGLLVKRASVNGDFYGCTSFPDCGFTKPL-------------------------------------------------------------------------------------------------------------------------------------
331 UniRef50_A6CAD3 Putative uncharacterized pr... 51 2e-05 1 29.4% 106:139 164:200 ---------------------------------------------------------------------------------------------------------CPKCQIPMVQrkGMKKGQSFWGCANYPECRETVW-----------------------------------------
332 UniRef50_A9VVE2 DNA topoisomerase n=18 Tax=... 50 2e-05 1 18.2% 4:80 619:692 ---QDMKAKDTIGKCPKCGKDVVNRKT----FYGCSGYKecKFSMSGEYLTKKISEANAKKLLEGKKTGLIKKMKGKSGK----------------------------------------------------------------------------------------------------
333 UniRef50_B9Z8V1 Restriction endonuclease n=... 50 3e-05 1 41.2% 13:46 245:283 ------------PSCPSCDSPMVLRVTQKgkFWGCSCFPACRGIRK--------------------------------------------------------------------------------------------------------------------------------------
334 UniRef50_Q0F390 Mrr restriction system prot... 50 3e-05 1 25.9% 85:142 278:338 ------------------------------------------------------------------------------------PDEIQSKLLQVATEGDYTTPTCPRCDTKLTLKkgKNAGNEFWGCRSYPRCRVTLKYKP--------------------------------------
335 UniRef50_C4FEN7 Putative uncharacterized pr... 50 3e-05 1 15.6% 49:138 624:713 ------------------------------------------------ERYPHAEERRLFYVAMTRCKKKIF-FVVDQTRPSRFIYELHDRICPNIFRGVSLPPQCPMCGSALAErtRNNPNSTFYGCTGYPFCTYVK------------------------------------------
336 UniRef50_C5A9C5 UvrD/REP helicase n=2 Tax=P... 50 3e-05 1 27.3% 71:136 847:911 ----------------------------------------------------------------------MFTARGQRSSFLRELEQDGAVSITDTDGQVVQEEECPSCRRGVLVLRNGPYGE-FRSCSNFPACKY--------------------------------------------
337 UniRef50_B7J8J6 Restriction endonuclease, p... 50 4e-05 1 31.6% 11:48 399:435 ----------TTPTCAKCGVKMVLKNG-YSEFWGCPNYPRCRETIRIR------------------------------------------------------------------------------------------------------------------------------------
338 UniRef50_A4AB42 Protein containing topoisom... 50 4e-05 1 41.7% 12:47 87:127 -----------NPLCPVCGSQMTVRVAKKgqFLGCTNFPRCRGTRQL-------------------------------------------------------------------------------------------------------------------------------------
339 UniRef50_B4DAT1 Restriction endonuclease n=... 50 4e-05 1 20.3% 3:61 380:438 --KLMGKVQLTPPTCPACEAAMDLVNASNGSVWVCSQRPDCRGRRCARKYQKATPPPAAKN-----------------------------------------------------------------------------------------------------------------------
340 UniRef50_C4XEP1 DNA topoisomerase n=2 Tax=M... 50 4e-05 1 15.7% 79:148 550:619 ------------------------------------------------------------------------------KRFNKTYENATETLELIAIALEYLNEKCPDDGGELIVRNNKRNDTKFVGCANFPKCHYARSVEGEENKRP--------------------------------
341 UniRef50_D2MH56 Helicase IV n=1 Tax=Candida... 50 5e-05 1 44.1% 13:46 850:884 ------------HLCPKCegFLTERRGPFGLFMGCSTYPLCSHTQQ--------------------------------------------------------------------------------------------------------------------------------------
342 UniRef50_B1F998 DNA topoisomerase n=1 Tax=B... 49 5e-05 1 28.0% 13:62 628:681 ------------RPCPVCegQLRRINGQDGPFWGCSNYKacKASYPDVNGEPNLAPKRKKPR----------------------------------------------------------------------------------------------------------------------
343 UniRef50_A3FPU5 DNA topoisomerase n=3 Tax=C... 49 6e-05 1 15.6% 38:172 661:799 -------------------------------------YKELKCPIDDFELLLFIDQKGKKSIFCPRCYNDPPFL--DAKENMLCKFCPHQTCNFSLKSTFFMACPSQDCRDGIITMDSSSTSDWRFDCSR---ckNICERLSLGERCEKCGSRKLkkEKTSQEHFVGCPNCD--------
344 UniRef50_C1MSJ2 DNA topoisomerase n=1 Tax=M... 49 6e-05 1 26.4% 10:62 806:862 ---------RASRRCPAcdGRLGLKLSKNGGFIGCSNytKCAYARPISTTNGDDAESMRTDP----------------------------------------------------------------------------------------------------------------------
345 UniRef50_B0SF59 DNA topoisomerase n=3 Tax=L... 49 7e-05 1 24.5% 85:137 569:621 ------------------------------------------------------------------------------------SEKKGNTKNQNQSLTYIENKTCPKCLDGYVKTKLGKNGKTIYFCSRYPHCDYI-------------------------------------------
346 UniRef50_C7GFF6 DNA topoisomerase n=11 Tax=... 49 7e-05 1 16.0% 6:149 1060:1202 -----EAPKLKDVKCPVCGGDMV--KTPFG--YGCANYKkcRFSVGQIAGVKLKEAQVKELLTNGKTGVIEGFIAKTGMKFDatKEGQITFDFPEKPKPVETTVKCPRCGELL------KKSQWYYECDCGFKVGHTVAKVPLSEAIIK-------------------------------
347 UniRef50_Q0VNZ0 Putative uncharacterized pr... 49 7e-05 1 22.5% 99:138 192:234 --------------------------------------------------------------------------------------------------FQAAAPACHKCGEAMVLRkgKQAGQTFWGCSAFPKCRGVR------------------------------------------
348 UniRef50_B6RA74 DNA topoisomerase n=6 Tax=A... 49 8e-05 1 34.1% 4:47 593:651 ---PDKEDGSDPRKCPKCdgRLSLKVSRFGAFVGCSNypHCDYTRQL-------------------------------------------------------------------------------------------------------------------------------------
349 UniRef50_Q1YVU1 Putative uncharacterized pr... 49 8e-05 1 14.7% 71:145 165:242 ----------------------------------------------------------------------ITAKRNYVASEVRSAIEPYLKKIQNHSESEPLIKLCPKCSSPLIERTSKkkGEMFLGCSAFPKCRFIDKSKETNA-----------------------------------
350 UniRef50_UPI0000DB782E PREDICTED: similar to topoi... 48 1e-04 1 15.7% 1:102 612:715 LENNFPSQDIAIFKCPKCGLDMTLKDRKQgkYIGCIGYPTCNNVIWFPQYIEDVEITDNICGCDPTFNELLNIRDSNIKSQNPITDDSGYRNTFDKANVSCS------------------------------------------------------------------------------
351 UniRef50_B5ENU5 Restriction endonuclease n=... 48 1e-04 1 31.6% 11:48 286:322 ----------TTPTCAKCGVKMVLKNG-YSEFWGCPNYPRCRETIRIR------------------------------------------------------------------------------------------------------------------------------------
352 UniRef50_A3BAP2 DNA topoisomerase n=6 Tax=P... 48 1e-04 1 39.5% 100:137 982:1020 ---------------------------------------------------------------------------------------------------DNDSRICPSCSEGTLRFKVSRYggYFIGCDRHPKCKYI-------------------------------------------
353 UniRef50_C5NYW8 DNA topoisomerase n=1 Tax=G... 48 1e-04 1 14.6% 2:104 579:671 -EDRFKHDNISGKKCEECGSFMLEVDKKGTKMLKCSS-PSCRNR---------KVISRLTNLRCDNCHKKMTLFGNGENATYRCQCGNSLKQKEVDKRIKSSKK----------------------------------------------------------------------------
354 UniRef50_C7RPH3 Restriction endonuclease n=... 48 1e-04 1 35.9% 11:49 298:338 ----------NVPSCPSCGVKMKRVSGKAGrfWGCGTFPRCHQKLGMRR-----------------------------------------------------------------------------------------------------------------------------------
355 UniRef50_Q74DF1 Mrr restriction system prot... 48 1e-04 1 32.4% 12:45 297:335 -----------TPTCPQCDLKMTLRENKSGkfWGCVRYPHCRQTL---------------------------------------------------------------------------------------------------------------------------------------
356 UniRef50_C1ZHH2 Nuclease-related protein/to... 48 2e-04 1 35.4% 4:51 176:228 ---SLADRHSSTTRCPKCGNDLIERQSQRGpfLGCKSYPRCRFTRQLSQEP---------------------------------------------------------------------------------------------------------------------------------
357 UniRef50_C4ZCE3 DNA topoisomerase n=5 Tax=C... 48 2e-04 1 19.5% 6:138 685:825 -----AARRKIGVKCPVCGGEIV--TTPFG--YGCANYKncNFNIGQVAGLDIPEEQVKKLIEEGITDTIRGFKSKSGKRFDACLKLNKDEQteNVKPQKVEGIVCPDCGGDIYV---SPYG---YRCANYNrcHFFV------------------------------------------
358 UniRef50_C5Z4V5 DNA topoisomerase (Fragment... 47 2e-04 1 35.7% 96:137 916:958 -----------------------------------------------------------------------------------------------FPDVDKDSRICPSCSEGTLRFKVSRYggYFIGCDRHPKCKYI-------------------------------------------
359 UniRef50_D1HI22 DNA topoisomerase (Fragment... 47 3e-04 1 34.2% 100:137 822:860 ---------------------------------------------------------------------------------------------------PDKSRTCPSCMEGTLIFKVSRFggYFIGCDQHPKCKYI-------------------------------------------
360 UniRef50_C2H7T8 DNA topoisomerase n=2 Tax=E... 47 3e-04 1 18.4% 6:92 387:470 -----MEQENVMGTCPKCQNSVVDK----GKFYGCSGYKdcKFTLPKRWSQKALTKKNVQDLLSKRETSLIKGFKSKKGSNFSAKLTLNDEM----------------------------------------------------------------------------------------
361 UniRef50_A7NI13 NERD domain protein n=1 Tax... 47 3e-04 1 32.6% 9:51 234:281 --------NQQVPRCPKCHALMIPRLAKKgwFYGCPNYPACREIHSIQNIP---------------------------------------------------------------------------------------------------------------------------------
362 UniRef50_B1ZVE8 Putative uncharacterized pr... 46 5e-04 1 23.7% 12:49 238:275 -----------TPTCPNCGVKMELVETATKPMWRCPNFPRCQRRMAARS-----------------------------------------------------------------------------------------------------------------------------------
363 UniRef50_B8L506 UvrD/REP helicase n=2 Tax=B... 46 5e-04 1 48.6% 8:44 880:917 -------AVINEERCPVCkgVFVERNGPHGPFRSCSSYPLCHNR----------------------------------------------------------------------------------------------------------------------------------------
364 UniRef50_A4G161 Putative restriction endonu... 46 5e-04 1 31.6% 12:49 270:303 -----------TPTCASCGIKLVKRKT----FWGCTNFPRCRTTIYFKN-----------------------------------------------------------------------------------------------------------------------------------
365 UniRef50_A9BWK3 Restriction endonuclease n=... 46 6e-04 1 29.3% 7:47 260:306 ------PAASPIPGCPQCGKAMVQRVAKRGpfWGCSAFGacRGTREM-------------------------------------------------------------------------------------------------------------------------------------
366 UniRef50_A0KLS7 DNA-binding protein n=3 Tax... 46 6e-04 1 20.0% 108:137 278:310 -----------------------------------------------------------------------------------------------------------RCGNTMVLrrGENKGNQFWGCSGFPKCRGV-------------------------------------------
367 UniRef50_C9A0J3 Predicted protein n=1 Tax=E... 46 7e-04 1 25.5% 91:141 206:257 ------------------------------------------------------------------------------------------EKHMFLNSLPEQVVKCPECESGFIVQKWNkkHSYFKGCTMFPECAHTESVS---------------------------------------
368 UniRef50_Q2SG76 Zn-finger domain associated... 45 0.001 1 41.0% 7:45 60:103 ------KPTQRVRICPQCGARMVSRRVKKGpfFSCSAYPKCTGVR---------------------------------------------------------------------------------------------------------------------------------------
369 UniRef50_A6VCC2 Restriction endonuclease n=... 45 0.002 1 24.3% 104:140 190:229 -------------------------------------------------------------------------------------------------------PACPLCDGAmvAKRGFNSGGEFWGCQKFPACRGVKEV----------------------------------------
370 UniRef50_A6GUS8 DNA topoisomerase n=1 Tax=L... 45 0.002 1 33.3% 15:47 624:658 --------------CPVCegKLRLLNGSKGAFWGCSGFRdcKTTCPD-------------------------------------------------------------------------------------------------------------------------------------
371 UniRef50_C9BIP8 DNA topoisomerase n=1 Tax=E... 44 0.002 1 17.2% 6:92 437:520 -----MEQENVMGTCSKCQNSVVDK----GKFYGCSGYKdcKFTLPKRWSQKALTKKNVQDLLSKRETSLIKGFKSKKGSNFSAKLTLNDEM----------------------------------------------------------------------------------------
372 UniRef50_A1SY33 Ribosome recycling factor n... 50 3e-05 1 14.4% 12:143 147:301 -----------GKSCSQCGREMQIQWPRTVkfWGCTGwrRCQHTEKMSSGDLSIFTRSDNPEAEVSNDELTTLVTMPEPSKIITERMDDVISDQKSQRRGTNDYRCPVHGELLVLRRKKNadQYFLGCSHWkgCSYIVKLKSV-------------------------------------
373 UniRef50_B7GJB8 Transposase n=14 Tax=Bacill... 49 8e-05 1 20.7% 88:179 83:176 ---------------------------------------------------------------------------------------KPIKRHTNTKTTVPDALTCPQCQAPSAYVYADNGGKGQYPCK-VCHCRfsRFAKQVIFRCPHCLKALEKIKERKDYYIHKCKNDDCSFYQTN-
374 UniRef50_C0XKW4 Transposase n=1 Tax=Lactoba... 49 8e-05 1 16.3% 82:179 77:178 ---------------------------------------------------------------------------------YQAKHGKPLKPVNHRQAFAFPRQTCPGCGAPSQYLYANGGgsSLLLC---KICQTSFnrKEVVLRCPDCQNKLELAKQRANFKVWRCNNRHCPHRKRE-
375 UniRef50_Q04HI0 DNA topoisomerase n=48 Tax=... 47 2e-04 1 21.1% 88:163 620:693 ---------------------------------------------------------------------------------------KNQKIVEIQDRQQEAIGRCPLCKEGMIVDKGK-----FYGCTNYKacRFTLPKKWSEKTIGKTAIKALITKGESNR-----------------
376 UniRef50_A9CRV1 DNA topoisomerase III n=1 T... 47 3e-04 1 22.1% 104:180 627:722 -------------------------------------------------------------------------------------------------------CWCKQIAVKKQVSKGKNRGKWFYSCYTFpkCDFFIWEGDktITC-DCGKPVIQKinNKGRKFYLcaYKKCKFFQWAD
377 UniRef50_UPI000196C8AD hypothetical protein CATMIT... 46 7e-04 1 14.7% 106:180 139:215 ---------------------------------------------------------------------------------------------------------CPYCGAPKEYIYDNSRGRGQYKC---KACKNTFTLKTTVKecPYYKHKLTLHHDRNGYLVYVCQNHDCSYYKHNK
378 UniRef50_B4CXA2 Restriction endonuclease n=... 45 0.001 1 22.9% 1:48 430:479 IDDFIAHARIFDPECPVCHNTMVIRHNrngpSWGCRNHPRCPGRREPR------------------------------------------------------------------------------------------------------------------------------------
379 UniRef50_Q1Q4X4 Putative uncharacterized pr... 45 0.001 1 14.9% 11:151 434:565 ----------KPGDCPVCGMHLEKKEMPVDETVTC--------------ICPQEWDPDTSPKSCPMCGM-MLQKSITVTSPTGEKIQKYVYMCPMACMTSDKPGECPDcgVGMKVKKTEHRKRTIYTCPMHPEVT-----SDKPDNCTRCG-----------------------------
380 UniRef50_B2AT59 Predicted CDS Pa_1_14755 n=... 45 0.001 1 21.6% 82:178 27:154 ---------------------------------------------------------------------------------RAKGSNPKSSRSSTTKGRKLRYGPCPTCKIGILERKRNnaGLWRLSCSRypPCRhiLWAQKQNepCPECHIGQLVERVKntEKYAECSrdGCNYIRP--
381 UniRef50_C0GTU6 DNA topoisomerase type IA z... 45 0.001 1 27.3% 98:141 6:52 -------------------------------------------------------------------------------------------------REKQNSIACPMCGSEMVLRRSKKGgtQFWGCSRYPRCRGTVNIA---------------------------------------
382 UniRef50_C8L8E9 DNA topoisomerase n=7 Tax=S... 45 0.002 1 14.6% 46:148 561:655 ---------------------------------------------QWEKYLNGISKGEKDDDSFINTINEMIKKTINEE----VKNKESIQKVAKEKVSTNNIAKCPACDNGYLIDRKG-----FYGCTEYNncEFTIPKKLLEKSIP--------------------------------
383 UniRef50_A5UJ54 Glutamate synthase, domain ... 45 0.002 1 14.6% 2:145 14:155 -EEKEGKSFKELEKCPDCKSDviMKKDMAYKTYECE---VCHYVYDEEK----EGQVLVKLGKCPVCGSPLSKFkkTEYRIYQCRICNYIHDEKTEKIPLKDLKECPDCGSDISNFEPAETNENNWLIS-FPK-QYIRNDESVRH-----------------------------------
384 UniRef50_C5JAZ8 Putative topoisomerase n=1 ... 44 0.002 1 30.0% 103:142 190:232 ------------------------------------------------------------------------------------------------------PRDCPRCGTPMGRRRVGKggKVVWVCGRYPDCRTVLELKE--------------------------------------
385 UniRef50_D1XWI9 Topoisomerase DNA-binding C... 44 0.002 1 16.8% 5:165 96:247 ----ETETRPIDAICPNCGGKII--QTRFG--YACVNhsLCSFIIPNFICNRYITVKEAED-FCNGNGDILDGFLNSHGKWFSA---YLTSGENGNVELSSIIGKCPACGQDFLI------GPTAFNCSNFrgCDFKIWRHYYGHKVNLHNAKELLTHGKLRRPF---------------
386 UniRef50_B4SNF4 UvrD/REP helicase n=2 Tax=S... 44 0.002 1 27.3% 71:136 845:909 ----------------------------------------------------------------------MFTLQGKRSPFLDELVKDGAVKVTAISGAAINEERCPVCKVGVFVDRNGPHG-TFRSCSSYPLCHN--------------------------------------------
387 UniRef50_C2UN45 DNA topoisomerase III n=5 T... 44 0.003 1 17.0% 1:88 637:724 IEEANRKEEEKkgSCLKCGSQVVLKKG----FYGCTGYStcDFQIKEKILGKKISSAQVKKLLKDGKTNTIKGFKKGEDLFDAVLSYN--------------------------------------------------------------------------------------------
388 UniRef50_A7K0B4 QueD-like protein n=35 Tax=... 43 0.004 1 13.3% 46:143 114:214 ---------------------------------------------NGQELSKGKVERQKLLIHVCKTANLPLIGASIKHSYQVGRLRRLLAAHIDLIEPDKEVRFCKKCGSPMIIKTASqkGRRFFTCSRQPNCTYTENYNVV-------------------------------------
389 UniRef50_C7I5R8 Restriction endonuclease n=... 43 0.004 1 13.9% 66:144 228:303 -----------------------------------------------------------------RHDLTLIDGSRLLRRIQAQPAEVQQHLLAIATDGDFWRVTCVNCGSKMTLKTNSTNGTRFWACGR---CRHTMPARQNE------------------------------------
390 UniRef50_C3CTB0 DNA topoisomerase n=1 Tax=B... 43 0.004 1 16.3% 11:133 602:729 ----------SLGSCPKCGKHVIEGK----KYYLCEAYKncDFLFGKTFLEAKITKAEIKKILSGKSSKELDFTKNGKTWKAKLAVNKDKGSIDMIFNSDTKkcKCPKCGGGI-----KETSKYFL-CENYKD-----------------------------------------------
391 UniRef50_B8G1K2 DNA topoisomerase n=2 Tax=D... 43 0.005 1 14.2% 2:107 672:776 -ESPASAAEENLGICPSCGGGVVERE----KGYGCQNWKncPFILWKNPICGKVLTPAQVKSLLKKGKTNLIkrSKNGSVFAAYLVWEDPSSGKLKFEFENNDRAKP-------------------------------------------------------------------------
392 UniRef50_Q48LE9 Topoisomerase domain protei... 43 0.005 1 16.7% 75:140 47:114 --------------------------------------------------------------------------QKPVKTSRAKRPEKRREPATPKLPAKPAAPACPHCKKTMVIkrTGKNAGEFWGCVAYPKCRGIRPI----------------------------------------
393 UniRef50_C5KB71 Putative uncharacterized pr... 43 0.005 1 22.6% 35:149 389:502 ----------------------------------CSN---CHRRIPRASLSLHELRCKRFYVQCPECRQPIRRERWdhVHCEVCKLPLDKEKLSDHCRVYHTPIECPDCGQQILQGRFGLLSHRRDSCSQRPhcRFCKLYVPIEGRSPE-------------------------------
394 UniRef50_A4IU08 DNA topoisomerase n=3 Tax=G... 43 0.006 1 21.0% 4:84 616:693 ---EEIKKENTIAPCPRckGYIVDRKT----FYGCTEYAncKQTFP-KSILGKTITKTHVKQLCEKGKTNKIKGFKGKKTFDAY------------------------------------------------------------------------------------------------
395 UniRef50_B7J7I8 DNA topoisomerase I, putati... 42 0.007 1 18.4% 93:168 554:645 --------------------------------------------------------------------------------------------DAMPTQARAQGRPCPIEGCDGTVRrkRKPGVFFWMCSnePGAPFAERVEAGDGpcPECGAATSRQETGKGYGYFRC------------
396 UniRef50_A8VW02 ABC transporter related n=1... 42 0.008 1 15.3% 8:105 166:261 -------SKEPLGPCPICGAQVMDK----GKFYGCEAynKCSFTLSKRIMKKTLPKTAVKNMLKSKESPVISGFQSKGKSFAASMIWSESEKRFIFDFKEPRKMK---------------------------------------------------------------------------
397 UniRef50_UPI0001C35497 hypothetical protein ChatD1... 42 0.008 1 27.6% 147:175 13:41 --------------------------------------------------------------------------------------------------------------------------------------------------CPHCSHALVHKKDRKHFIVHKCVNPKCPY-----
398 UniRef50_Q02GM2 DNA topoisomerase n=10 Tax=... 42 0.008 1 18.0% 82:142 567:630 ---------------------------------------------------------------------------------PSAQDEPRASSTASISSAPTSDFLCGKCGLPLVHRKkgKGGFDFWGCSGYrgCKVSYPTKS--------------------------------------
399 UniRef50_B3E4Q9 MJ0042 family finger-like p... 42 0.008 1 14.6% 86:167 8:89 -------------------------------------------------------------------------------------CKASGTINDLEIPDDGMMLACPRCKESFRVEKPRKKATSAFATNTCPSCGYSTFCEEVFDECPHCGLDVKTVIERKRKEDVQ-------------
400 UniRef50_B1HX02 DNA topoisomerase III n=93 ... 42 0.009 1 16.2% 2:100 629:725 -QKKYKKEKTVVGKCILCNGSII----DHGTFYGCSNYknCKFSVSKKILSKTISQTNVRKLLATGETDMIKGFKKGQKTFNAHLIWDKQEHRVHFKFPQ--------------------------------------------------------------------------------
401 UniRef50_B7G3B1 DNA topoisomerase n=2 Tax=B... 42 0.009 1 18.5% 3:159 760:921 --KTEQEDNGPPVKCPICQFQVIRIL--RGEGYEGNGYHVCPKCFSDPPSDHG-GASNAGDFRCFACQHPtaLASGTPGGDVEVFRCPFCHPSAQPTSTSDSGKVC--------VRKTSR--GYVLSCNKydRCSYTIWLPkqNEICGRCSSPRAVIRK---------------------
402 UniRef50_C3RPW1 DNA topoisomerase n=1 Tax=M... 42 0.010 1 12.7% 11:136 615:729 ----------SKIKCPECGGGLLV----SSKVVKCQH---CNFILFPIVASKKLSETNIKDLIEKKETKLikSKTGNSFDAKLKLVKANDKWAVQFDFTKQILGKCPRCGGDIVEGVKG------FSCEN-KNCEF--------------------------------------------
403 UniRef50_C5VLI1 Putative DNA topoisomerase ... 42 0.011 1 19.3% 12:146 93:220 -----------DGVCPLCGGR--IRKTSKG--YRCEnhPSCDFMIPGIICNRRITEQDAVAFLNGKHIALEGFASNEWKMFASSLSIAEGK-----VKLESRIAKCPHCGGDLHV------GLKAYNCANYRncKFSIWRNISGHA----------------------------------
404 UniRef50_Q8R819 Transposase n=2 Tax=Thermoa... 42 0.011 1 14.3% 83:173 73:170 ----------------------------------------------------------------------------------AEAQGKPISHVRRIKPLCVDVDNCPVCGAPPDYLYsgKDPDGflQC---KVCKH-QWAPGKPApcPFCGSALIQDKTRKNFTVFKCRNDNC-------
405 UniRef50_C4L3B0 DNA topoisomerase n=2 Tax=E... 42 0.011 1 25.4% 2:60 617:672 -KKGTTRPKASFGICPNCGKGLVE----HPKFIGCSGYRecRFTVSKQVLGVGLVKDELK------------------------------------------------------------------------------------------------------------------------
406 UniRef50_A7AYT5 Putative uncharacterized pr... 42 0.014 1 14.9% 4:164 351:529 ---EENYPYMNKIYCAKCGHPLYKRIYSKGnnWGCSGMKrcDGINIPDgwHFEENTYIDEKASDKGVKEFSYLKERSWKRRHKKKQPPTIPENTEAEYPYREKIYCALCGSRLVRHVDTKSHKVTWVCNGRKrcDGTrpDTILKGWGEIKKDIYIQRKDDKNGK----------------
407 UniRef50_UPI00019094F4 putative helicase IV n=1 Ta... 41 0.015 1 20.9% 68:134 40:106 -------------------------------------------------------------------GVYIVTNSRQPSRYIRELCEIAGAEVRFETTEGAVLRQCPTCLVGQIIEIRNRDGSVFCGCNQFPDC----------------------------------------------
408 UniRef50_Q22YB4 Putative uncharacterized pr... 41 0.015 1 13.0% 15:176 117:263 --------------CLTCQTPLIYKLSTK----------TCASKCDQNEFINSSNQCQLCDSSCASCKESGPDKCLTCNQNMFLFNGYCAELCPNGYQSNTKLLTCNSCN-----IKTSPD------csCYPTCQLCNKDSAQDKKCITCYTETMRLDVNQNCV---CLNPkcSYQ----
409 UniRef50_B1V6J5 Topoisomerase DNA-binding C... 41 0.017 1 28.3% 96:141 210:260 -----------------------------------------------------------------------------------------------NKKMRYINRACPKCGRKMIVQKNSSTGENFLGCTNfeKCRGNISIK---------------------------------------
410 UniRef50_C7HY28 DNA topoisomerase III n=1 T... 41 0.018 1 24.0% 106:180 613:704 ---------------------------------------------------------------------------------------------------------CPACGGGRCAQRTSKAGATYHRC---LDCDAAfkAPASGPKCLSCKKPTFKNETKTGKPYYRC--GGCKGAWWPD
411 UniRef50_C7WLR4 Type I topoisomerase (Fragm... 41 0.020 1 17.9% 13:96 14:93 ------------GKCPKCGNNIVLKKS----FYGCSNYPECTFTLAEHFRKKKLTKTNVKELLEGKETLVKGIKTKDRKSYNAVVKIGEKGYIDFI------------------------------------------------------------------------------------
412 UniRef50_A8H8V9 NERD domain protein n=9 Tax... 41 0.020 1 23.3% 105:177 286:352 --------------------------------------------------------------------------------------------------------RCKHCGEST--NYTPMYGKFGY----YINCNQCTKNTPMKQACPQCSSKNTRVKKSKETYTLSCQECGCGQRV---
413 UniRef50_A9V3W6 DNA topoisomerase n=1 Tax=M... 41 0.021 1 17.3% 14:163 577:739 -------------RCGKCNRYMKYVSAKPQRLY-C---PTCDETFALPQGGKIVLYKELRCPL-DKFELLMFTTGTTGRAYPLCPYCYNNPPFEDMDknDCTHPTccECGGQLVLDASSKP--KWRLCCN--RCnnAHSIKITKTPCEACGAMEVDVEFNKTK-----------------
414 UniRef50_A4BJY7 Topoisomerase I n=1 Tax=Rei... 41 0.022 1 11.0% 49:157 544:669 ------------------------------------------------NQSSISQFEQGTQEACIQCGHPIkkKSNPKQFFweGCEKFIDDMRGKPYMADLQSHQCKLCNGDLERAYSKAKNRHFWVHKDDSDCAKRTYQDRSGKpcPGCGFALVRR-----------------------
415 UniRef50_A2DRV7 DnaJ domain containing prot... 41 0.023 1 13.8% 74:160 128:215 -------------------------------------------------------------------------YNGTDKKVHIQRNKICSKCHGNGTKDGNPPQKCNKcgSGVVLESYRRGNTYFQTSSDCPVCHGTGLYIAKSDVCPNCKGDKVVRENK--------------------
416 UniRef50_B6ADG7 DNA topoisomerase n=1 Tax=C... 41 0.023 1 17.3% 14:169 645:820 -------------KCGQCKRYMTYISNTNPPKLYCS---FCEINLKLPSGGSLKLYKELKCPlcPRCYNDPPFDSAIQ--NILCKECPHPTCPHSYNSSFIMYCPVEKCKDGVLTLDLSSAPNWRIDCSnfRE-KHCHKVSTTNDYCNNCGARILLInnSPKESIIGCP-----------
417 UniRef50_D0NZ98 DNA topoisomerase, putative... 41 0.024 1 11.9% 46:180 635:783 ---------------------------------------------PRGEARPRTPVDIEPRHVIRDRRRKRQRLPSRPTDNSAQAQRRILRAPSLTSDIPRCDDHGLPCVEKEVTRDGPNTGRMFYKCsqGEQCDFFAWVSDSNApcPGHNEPCAERTVKKDGpfYIctDNSCGFFLWKD
418 UniRef50_B7VPA6 Zn-finger domain associated... 40 0.026 1 18.3% 62:143 135:218 -------------------------------------------------------------HVCKSAGLPLIGASIKHS-YQVSRLKRLLAAHIDLIEPSKEVRFCKKCSSPMIIKLAShkGRRFFTCSRQPNCTYTENYNVV-------------------------------------
419 UniRef50_C1SNP4 Nuclease-like protein n=1 T... 40 0.026 1 12.1% 76:174 211:299 ---------------------------------------------------------------------------NNHTPVNSSAPSGAVNKAKTECSVSKSFPVCKHCNGTIVEVLYGKYG-YYLKCS---DCEGNTSI---RENCSACGKQ-LRVRKEKERFFLECS--DCD------
420 UniRef50_Q4RZA1 Chromosome 1 SCAF14944, who... 40 0.031 1 12.5% 36:179 190:332 -----------------------------------TSHPADPQEITSISSSSLTSKAQSSTDTCVPKDSTDLAVSLVTLKGNKSVADSDVPVLPKQEEPAQMVAFVPAQSVKTYTRRGRGR------CPN-PGCSFIYVTRHKPPTCPECGHHllSTARGRGR----CKNPSCDYMYKN-
421 UniRef50_A5GDE5 MJ0042 family finger-like p... 40 0.034 1 18.2% 86:151 8:74 -------------------------------------------------------------------------------------CKISGQISDAKVPAEGIMMNCPKCKTPFRVKRDAASGWQSGDcsICPGCHYSTFSDETFDICPKCG-----------------------------
422 UniRef50_B0K4X0 Integrase, catalytic region... 40 0.050 1 17.6% 105:178 8:87 --------------------------------------------------------------------------------------------------------KCPKCNNTHLFYKYGKDKDGyyLC---RKchQFAPDKPSPKkcPVCGKSSFLHHDYEYYSNYRCSDKKCNHSFF--
423 UniRef50_C3WQ11 DNA topoisomerase n=4 Tax=F... 40 0.051 1 15.8% 3:141 615:744 --KPSVEFIESLGKCPKCGGKVFERA----KTYSCEnwKESKHYKEKFSINSEEAKKFLANET-VQCTLTSEDKKTRKVNLKMKLNGEYV----NFEEERESVGKCPICGKEVVESE-----KMFY-CTGNKdcIFKLWKE---------------------------------------
424 UniRef50_C1E2E8 Predicted protein n=1 Tax=M... 39 0.059 1 12.2% 33:179 520:667 --------------------------------FACPNRPRCEWMGTRAGVEDHLEECLHEVIPCGFVDSFKDKCAGTC-----AVTLPRVQMLAHKEICRYQSAVCKHCGESMALRRHGQhsARFYEC---PNchKLRKVQHDGTVCPGVRVECMYRSYGCDERVLKCDyrHCRERFDE-
425 UniRef50_UPI000186EA7F DNA topoisomerase 3-alpha, ... 39 0.065 1 14.0% 82:174 598:701 ---------------------------------------------------------------------------------NSYIQGNNPISSEKENNVPKSPMNCRECGNPMI--KEIKNNKISFSCSNKSQcnTVKDVEITNDSCPKCGSnfKNKNKNRSVKDIGCLN-GCD------
426 UniRef50_B2W184 CHY zinc finger domain cont... 39 0.065 1 15.7% 35:155 195:318 ----------------------------------CRRWYTCRHCHDAVEDHNLNRK-MTQNMLCMVCGTPQSASDCCKNCETEAACYYCDICKLWDNNSKKKIYHCPDCG---ICRRGEGLGKDFYHCKSCNVcsHKCLPAATEGDCPICGDHLF-------------------------
427 UniRef50_A8VWK2 Uncharacterized protein inv... 39 0.066 1 18.2% 91:178 141:227 ------------------------------------------------------------------------------------------KQVADIIHEFDVMGTCPCCGEPHRLAKLMNKGEKHLNC---PRCE-TLW-KQKRLACVHCGNdyINVKDDEKAKIEVC--ETCKNYLK--
428 UniRef50_B0ERJ9 DNA topoisomerase n=2 Tax=E... 39 0.084 1 14.5% 14:178 619:794 -------------KCGKCGRILLKVIG-DQTYLScsQQTKCCPICKFETIMTSSLKSTKKEMVCPGCYNEKNQFMKQE----HSSCLQCSNPECKLSYERTKTCLCSVCGGVMCLSSLQNK----WSCFC-NTCdhMEWIdpNDEICGKCkyHLVDLTMKDNTVIKGCMN--CDSTIK--
consensus/100% ....................................................................................................................................................................................
consensus/90% ....................................................................................................................................................................................
consensus/80% .................................................................................................................................................................................
consensus/70% ......................................................................................................h.....................................................................
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