Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP60560
DateThu Jan 5 12:06:53 GMT 2012
Unique Job IDb8ef9f9fb741b229

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1pvna1
Top template information
Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
Confidence and coverage
Confidence:100.0% Coverage: 97%
337 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSWSGVPIIAANMDTVGTF
Secondary structure 
SS confidence 
Disorder  ???????
?
??????????
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  SMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLN
Secondary structure 
SS confidence 
Disorder 
??
??
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  PALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGI
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  GPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTTPGDVAKAFGGGADFVM
Secondary structure 
SS confidence 
Disorder 
????
????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  LGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGP
Secondary structure 
SS confidence 
Disorder 
????????
Disorder confidence 
 
   .........310.........320.........330.........340.......
Sequence  VENTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNNL
Secondary structure 
SS confidence 
Disorder 
??????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1pvn chain A domain 1

3D model

Region: 2 - 342
Aligned: 337
Modelled: 341
Confidence: 100.0%
Identity: 27%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 1jr1 chain A domain 1

3D model

Region: 3 - 342
Aligned: 325
Modelled: 340
Confidence: 100.0%
Identity: 25%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 1zfj chain A domain 1

3D model

Region: 4 - 342
Aligned: 327
Modelled: 338
Confidence: 100.0%
Identity: 31%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 2a7r chain D

3D model

Region: 3 - 339
Aligned: 314
Modelled: 315
Confidence: 100.0%
Identity: 69%
PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)

Phyre2

PDB 2cu0 chain A domain 1

3D model

Region: 3 - 342
Aligned: 329
Modelled: 340
Confidence: 100.0%
Identity: 31%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 1zfj chain A

3D model

Region: 6 - 342
Aligned: 326
Modelled: 337
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes

Phyre2

PDB 2cu0 chain B

3D model

Region: 3 - 342
Aligned: 329
Modelled: 340
Confidence: 100.0%
Identity: 31%
PDB header:oxidoreductase
Chain: B: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase from2 pyrococcus horikoshii ot3

Phyre2

PDB 1me9 chain A

3D model

Region: 2 - 338
Aligned: 321
Modelled: 337
Confidence: 100.0%
Identity: 29%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound

Phyre2

PDB 3r2g chain A

3D model

Region: 8 - 341
Aligned: 319
Modelled: 328
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila

Phyre2

PDB 1vrd chain A domain 1

3D model

Region: 6 - 337
Aligned: 304
Modelled: 312
Confidence: 100.0%
Identity: 35%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 1vrd chain A

3D model

Region: 6 - 337
Aligned: 307
Modelled: 312
Confidence: 100.0%
Identity: 36%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution

Phyre2

PDB 1eep chain A

3D model

Region: 6 - 339
Aligned: 300
Modelled: 306
Confidence: 100.0%
Identity: 33%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 3khj chain E

3D model

Region: 2 - 339
Aligned: 296
Modelled: 309
Confidence: 100.0%
Identity: 30%
PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64

Phyre2

PDB 1jcn chain A

3D model

Region: 3 - 330
Aligned: 279
Modelled: 285
Confidence: 100.0%
Identity: 31%
PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp

Phyre2

PDB 1jcn chain A domain 1

3D model

Region: 3 - 330
Aligned: 279
Modelled: 285
Confidence: 100.0%
Identity: 29%
Fold: TIM beta/alpha-barrel
Superfamily: Inosine monophosphate dehydrogenase (IMPDH)
Family: Inosine monophosphate dehydrogenase (IMPDH)

Phyre2

PDB 1ypf chain B

3D model

Region: 8 - 339
Aligned: 293
Modelled: 302
Confidence: 100.0%
Identity: 31%
PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution

Phyre2

PDB 3ffs chain C

3D model

Region: 4 - 339
Aligned: 290
Modelled: 306
Confidence: 100.0%
Identity: 31%
PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase

Phyre2

PDB 2qr6 chain A

3D model

Region: 1 - 334
Aligned: 312
Modelled: 334
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase;
PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution

Phyre2

PDB 2zrv chain C

3D model

Region: 4 - 334
Aligned: 278
Modelled: 286
Confidence: 100.0%
Identity: 20%
PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.

Phyre2

PDB 2a7n chain A

3D model

Region: 1 - 335
Aligned: 262
Modelled: 291
Confidence: 100.0%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase

Phyre2
1
d1pvna1
2
d1jr1a1
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d1zfja1
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c2a7rD_
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d2cu0a1
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c1zfjA_
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c2cu0B_
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c1me9A_
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c3r2gA_
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d1vrda1
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c1vrdA_
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d1eepa_
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c3khjE_
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c1jcnA_
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d1jcna1
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c1ypfB_
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c3ffsC_
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c2qr6A_
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c2zrvC_
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c2a7nA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1pvna1
100.0 27 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
2d1jr1a1
100.0 25 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
3d1zfja1
100.0 31 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
4c2a7rD_
100.0 69 PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)
5d2cu0a1
100.0 31 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
6c1zfjA_
100.0 34 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
7c2cu0B_
100.0 31 PDB header:oxidoreductase
Chain: B: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase from2 pyrococcus horikoshii ot3
8c1me9A_
100.0 29 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound
9c3r2gA_
100.0 34 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
10d1vrda1
100.0 35 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
11c1vrdA_
100.0 36 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution
12d1eepa_
100.0 33 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
13c3khjE_
100.0 30 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
14c1jcnA_
100.0 31 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp
15d1jcna1
100.0 29 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
16c1ypfB_
100.0 31 PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution
17c3ffsC_
100.0 31 PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase
18c2qr6A_
100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase;
PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution
19c2zrvC_
100.0 20 PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.
20c2a7nA_
100.0 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase
21d1p0ka_
not modelled 100.0 20 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
22d1p4ca_
not modelled 100.0 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
23d1kbia1
not modelled 100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
24d1tb3a1
not modelled 100.0 23 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
25c1kbiB_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:cytochrome b2;
PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme
26c2e77B_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate oxidase;
PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex
27d1goxa_
not modelled 100.0 21 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
28c2rduA_
not modelled 100.0 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyacid oxidase 1;
PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate
29d1vcfa1
not modelled 100.0 21 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
30c2cdh1_
not modelled 100.0 20 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
31c3bw2A_
not modelled 100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-nitropropane dioxygenase;
PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes
32c2gjlA_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
33c3bo9B_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
34c2z6jB_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
35d1ofda2
not modelled 100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
36d1ea0a2
not modelled 100.0 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
37d1juba_
not modelled 100.0 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
38c3oixA_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate
PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans
39c2vdcF_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: F: PDB Molecule:glutamate synthase [nadph] large chain;
PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications.
40c1lm1A_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase;
PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme
41d2b4ga1
not modelled 100.0 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
42d1uuma_
not modelled 100.0 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
43c3gyeA_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, putative;
PDBTitle: didydroorotate dehydrogenase from leishmania major
44d1ep3a_
not modelled 100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
45d1d3ga_
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
46c2fptA_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors
47d1tv5a1
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
48c1tv5A_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial;
PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor
49d1gtea2
not modelled 99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
50d1f76a_
not modelled 99.9 11 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
51c2htmB_
not modelled 99.9 14 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
52d1vhna_
not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
53c3b0vD_
not modelled 99.8 10 PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna
54c1gthD_
not modelled 99.7 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
55d1y0ea_
not modelled 99.7 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
56d1yxya1
not modelled 99.6 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
57c3igsB_
not modelled 99.6 15 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
58d1xm3a_
not modelled 99.6 13 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
59c3q58A_
not modelled 99.6 15 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
60d1wv2a_
not modelled 99.5 13 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
61c3gr7A_
not modelled 99.5 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
62c2vkzH_
not modelled 99.5 9 PDB header:transferase
Chain: H: PDB Molecule:fatty acid synthase subunit beta;
PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex
63d1ps9a1
not modelled 99.5 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
64c2uvaI_
not modelled 99.5 11 PDB header:transferase
Chain: I: PDB Molecule:fatty acid synthase beta subunits;
PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the beta subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400
65c3qjaA_
not modelled 99.5 15 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
66c2h90A_
not modelled 99.5 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
67d1djqa1
not modelled 99.4 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
68c3hf3A_
not modelled 99.4 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
69c3kruC_
not modelled 99.4 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
70c1djnB_
not modelled 99.4 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
71c1ps9A_
not modelled 99.4 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
72d1geqa_
not modelled 99.3 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
73d1xcfa_
not modelled 99.3 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
74c2c3zA_
not modelled 99.3 10 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
75d1qopa_
not modelled 99.3 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
76d1rd5a_
not modelled 99.3 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
77d1z41a1
not modelled 99.3 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
78d1a53a_
not modelled 99.2 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
79c2w6rA_
not modelled 99.2 19 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
80d1vyra_
not modelled 99.2 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
81c3k30B_
not modelled 99.2 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex
82d1ka9f_
not modelled 99.2 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
83d1vc4a_
not modelled 99.2 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
84c3gkaB_
not modelled 99.2 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:n-ethylmaleimide reductase;
PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei
85d1h5ya_
not modelled 99.1 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
86c3navB_
not modelled 99.1 16 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
87c2v82A_
not modelled 99.0 18 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
88c2gq8A_
not modelled 99.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, fmn-binding;
PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone
89d1wa3a1
not modelled 99.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
90d1wbha1
not modelled 99.0 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
91d1thfd_
not modelled 99.0 20 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
92d1gwja_
not modelled 99.0 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
93d1vjia_
not modelled 99.0 20 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
94d1piia2
not modelled 99.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
95c2ekcA_
not modelled 99.0 16 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
96c2y85D_
not modelled 98.9 16 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
97d1j5ta_
not modelled 98.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
98c1znnF_
not modelled 98.9 17 PDB header:biosynthetic protein
Chain: F: PDB Molecule:plp synthase;
PDBTitle: structure of the synthase subunit of plp synthase
99d1znna1
not modelled 98.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:PdxS-like
100d1i4na_
not modelled 98.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
101c3l5aA_
not modelled 98.8 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus
102c3tdmD_
not modelled 98.8 16 PDB header:de novo protein
Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel
PDBTitle: computationally designed tim-barrel protein, halfflr
103d1vhca_
not modelled 98.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
104c3thaB_
not modelled 98.8 11 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
105d1vzwa1
not modelled 98.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
106d1n7ka_
not modelled 98.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
107d1mxsa_
not modelled 98.7 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
108d1xi3a_
not modelled 98.7 22 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
109d1w0ma_
not modelled 98.7 11 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
110d1jvna1
not modelled 98.7 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
111d2flia1
not modelled 98.6 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
112d1icpa_
not modelled 98.6 21 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
113d1tqxa_
not modelled 98.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
114d1oyaa_
not modelled 98.6 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
115c1piiA_
not modelled 98.6 17 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
116d1o0ya_
not modelled 98.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
117c3labA_
not modelled 98.6 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
118d1h1ya_
not modelled 98.5 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
119d1hg3a_
not modelled 98.5 13 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
120d1qapa1
not modelled 98.5 20 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0