Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	T	H	N	F	N	T	L	D	L	L	T	S	P	V	W	I	V	S	P	F	E	E	Q	L	I	Y	A	N	S	A	A	K	L	L	M	Q	D	L	T	F	S	Q	L	R	T	G	P	Y	S	V	S	S	Q	K	E	L	P	K
Secondary structure
SS confidence
Disorder		?	?	?																																							?				?	?	?	?		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	L	S	D	L	Q	N	Q	H	D	I	I	E	I	L	T	V	Q	R	K	E	E	E	T	A	L	S	C	R	L	V	L	R	K	L	T	E	T	E	P	V	I	I	F	E	G	I	E	A	P	A	T	L	G	L	K	A	S	R	S
Secondary structure
SS confidence
Disorder																																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	N	Y	Q	R	K	K	Q	G	F	Y	A	R	F	F	L	T	N	S	A	P	M	L	L	I	D	P	S	R	D	G	Q	I	V	D	A	N	L	A	A	L	N	F	Y	G	Y	N	H	E	T	M	C	Q	K	H	T	W	E	I	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		M	L	G	R	R	V	M	P	I	M	H	E	I	S	H	L	P	G	G	H	K	P	L	N	F	V	H	K	L	A	D	G	S	T	R	H	V	Q	T	Y	A	G	P	I	E	I	Y	G	D	K	L	M	L	C	I	V	H	D	I	T
Secondary structure
SS confidence
Disorder																	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	Q	K	R	L	E	E	Q	L	E	H	A	A	H	H	D	A	M	T	G	L	L	N	R	R	Q	F	Y	H	I	T	E	P	G	Q	M	Q	H	L	A	I	A	Q	D	Y	S	L	L	L	I	D	T	D	R	F	K	H	I	N	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	Y	G	H	S	K	G	D	E	V	L	C	A	L	A	R	T	L	E	S	C	A	R	K	G	D	L	V	F	R	W	G	G	E	E	F	V	L	L	L	P	R	T	P	L	D	T	A	L	S	L	A	E	T	I	R	V	S	V	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410
Sequence		K	V	S	I	S	G	L	P	R	F	T	V	S	I	G	V	A	H	H	E	G	N	E	S	I	D	E	L	F	K	R	V	D	D	A	L	Y	R	A	K	N	D	G	R	N	R	V	L	A	A
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?																																						?					?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1w25 chain B Region: 237 - 409 Aligned: 173 Modelled: 173 Confidence: 100.0% Identity: 38% PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp Phyre2 PDB 3ezu chain A Region: 210 - 409 Aligned: 194 Modelled: 200 Confidence: 100.0% Identity: 27% PDB header:signaling protein Chain: A: PDB Molecule:ggdef domain protein; PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution Phyre2 PDB 3i5a chain A Region: 243 - 409 Aligned: 167 Modelled: 167 Confidence: 100.0% Identity: 41% PDB header:signaling protein Chain: A: PDB Molecule:response regulator/ggdef domain protein; PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae Phyre2 PDB 3bre chain A Region: 243 - 408 Aligned: 166 Modelled: 166 Confidence: 100.0% Identity: 40% PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: crystal structure of p.aeruginosa pa3702 Phyre2 PDB 3qyy chain B Region: 248 - 408 Aligned: 154 Modelled: 161 Confidence: 100.0% Identity: 31% PDB header:signaling protein/inhibitor Chain: B: PDB Molecule:response regulator; PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp Phyre2 PDB 3ign chain A Region: 251 - 410 Aligned: 160 Modelled: 156 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:diguanylate cyclase; PDBTitle: crystal structure of the ggdef domain from marinobacter2 aquaeolei diguanylate cyclase complexed with c-di-gmp -3 northeast structural genomics consortium target mqr89a Phyre2 PDB 3i5c chain A Region: 241 - 409 Aligned: 169 Modelled: 169 Confidence: 100.0% Identity: 39% PDB header:signaling protein Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa Phyre2 PDB 3i5b chain A Region: 252 - 410 Aligned: 159 Modelled: 159 Confidence: 100.0% Identity: 37% PDB header:signaling protein Chain: A: PDB Molecule:wspr response regulator; PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa Phyre2 PDB 3hva chain A Region: 252 - 407 Aligned: 156 Modelled: 156 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:protein fimx; PDBTitle: crystal structure of fimx ggdef domain from pseudomonas2 aeruginosa Phyre2 PDB 1w25 chain A domain 3 Region: 258 - 409 Aligned: 152 Modelled: 152 Confidence: 100.0% Identity: 41% Fold: Ferredoxin-like Superfamily: Nucleotide cyclase Family: GGDEF domain Phyre2 PDB 3icl chain A Region: 256 - 408 Aligned: 153 Modelled: 153 Confidence: 100.0% Identity: 33% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:eal/ggdef domain protein; PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium3 target mcr174c Phyre2 PDB 3mtk chain A Region: 248 - 408 Aligned: 153 Modelled: 161 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase; PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c Phyre2 PDB 3pjw chain A Region: 239 - 410 Aligned: 171 Modelled: 172 Confidence: 99.9% Identity: 27% PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 Phyre2 PDB 3hvw chain A Region: 262 - 408 Aligned: 145 Modelled: 147 Confidence: 99.9% Identity: 15% PDB header:lyase Chain: A: PDB Molecule:diguanylate-cyclase (dgc); PDBTitle: crystal structure of the ggdef domain of the pa2567 protein2 from pseudomonas aeruginosa, northeast structural genomics3 consortium target par365c Phyre2 PDB 3p7n chain B Region: 131 - 310 Aligned: 180 Modelled: 180 Confidence: 99.7% Identity: 14% PDB header:dna binding protein Chain: B: PDB Molecule:sensor histidine kinase; PDBTitle: crystal structure of light activated transcription factor el222 from2 erythrobacter litoralis Phyre2 PDB 3gec chain A Region: 16 - 266 Aligned: 230 Modelled: 230 Confidence: 99.6% Identity: 10% PDB header:circadian clock protein Chain: A: PDB Molecule:period circadian protein; PDBTitle: crystal structure of a tandem pas domain fragment of2 drosophila period Phyre2 PDB 3gfz chain B Region: 249 - 406 Aligned: 131 Modelled: 133 Confidence: 99.5% Identity: 13% PDB header:hydrolase, signaling protein Chain: B: PDB Molecule:klebsiella pneumoniae blrp1; PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex Phyre2 PDB 3rty chain A Region: 16 - 284 Aligned: 255 Modelled: 258 Confidence: 99.5% Identity: 10% PDB header:circadian clock protein Chain: A: PDB Molecule:period circadian protein; PDBTitle: structure of an enclosed dimer formed by the drosophila period protein Phyre2 PDB 3gdi chain B Region: 16 - 284 Aligned: 233 Modelled: 249 Confidence: 99.5% Identity: 10% PDB header:transcription Chain: B: PDB Molecule:period circadian protein homolog 2; PDBTitle: mammalian clock protein mper2 - crystal struture of a pas2 domain fragment Phyre2 PDB 3bwl chain A Region: 116 - 239 Aligned: 123 Modelled: 124 Confidence: 99.5% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of pas domain of htr-like protein from haloarcula2 marismortui Phyre2 1 c1w25B_ 2 c3ezuA_ 3 c3i5aA_ 4 c3breA_ 5 c3qyyB_ 6 c3ignA_ 7 c3i5cA_ 8 c3i5bA_ 9 c3hvaA_ 10 d1w25a3 11 c3iclA_ 12 c3mtkA_ 13 c3pjwA_ 14 c3hvwA_ 15 c3p7nB_ 16 c3gecA_ 17 c3gfzB_ 18 c3rtyA_ 19 c3gdiB_ 20 c3bwlA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1w25B_ 100.0 38 PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp 2 c3ezuA_ 100.0 27 PDB header:signaling protein Chain: A: PDB Molecule:ggdef domain protein; PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution 3 c3i5aA_ 100.0 41 PDB header:signaling protein Chain: A: PDB Molecule:response regulator/ggdef domain protein; PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae 4 c3breA_ 100.0 40 PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: crystal structure of p.aeruginosa pa3702 5 c3qyyB_ 100.0 31 PDB header:signaling protein/inhibitor Chain: B: PDB Molecule:response regulator; PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp 6 c3ignA_ 100.0 36 PDB header:transferase Chain: A: PDB Molecule:diguanylate cyclase; PDBTitle: crystal structure of the ggdef domain from marinobacter2 aquaeolei diguanylate cyclase complexed with c-di-gmp -3 northeast structural genomics consortium target mqr89a 7 c3i5cA_ 100.0 39 PDB header:signaling protein Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa 8 c3i5bA_ 100.0 37 PDB header:signaling protein Chain: A: PDB Molecule:wspr response regulator; PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa 9 c3hvaA_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:protein fimx; PDBTitle: crystal structure of fimx ggdef domain from pseudomonas2 aeruginosa 10 d1w25a3 100.0 41 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:GGDEF domain 11 c3iclA_ 100.0 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:eal/ggdef domain protein; PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium3 target mcr174c 12 c3mtkA_ 100.0 25 PDB header:transferase Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase; PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c 13 c3pjwA_ 99.9 27 PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 14 c3hvwA_ 99.9 15 PDB header:lyase Chain: A: PDB Molecule:diguanylate-cyclase (dgc); PDBTitle: crystal structure of the ggdef domain of the pa2567 protein2 from pseudomonas aeruginosa, northeast structural genomics3 consortium target par365c 15 c3p7nB_ 99.7 14 PDB header:dna binding protein Chain: B: PDB Molecule:sensor histidine kinase; PDBTitle: crystal structure of light activated transcription factor el222 from2 erythrobacter litoralis 16 c3gecA_ 99.6 10 PDB header:circadian clock protein Chain: A: PDB Molecule:period circadian protein; PDBTitle: crystal structure of a tandem pas domain fragment of2 drosophila period 17 c3gfzB_ 99.5 13 PDB header:hydrolase, signaling protein Chain: B: PDB Molecule:klebsiella pneumoniae blrp1; PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex 18 c3rtyA_ 99.5 10 PDB header:circadian clock protein Chain: A: PDB Molecule:period circadian protein; PDBTitle: structure of an enclosed dimer formed by the drosophila period protein 19 c3gdiB_ 99.5 10 PDB header:transcription Chain: B: PDB Molecule:period circadian protein homolog 2; PDBTitle: mammalian clock protein mper2 - crystal struture of a pas2 domain fragment 20 c3bwlA_ 99.5 16 PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of pas domain of htr-like protein from haloarcula2 marismortui 21 d1ew0a_ not modelled 99.4 19 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Heme-binding PAS domain 22 c1wa9A_ not modelled 99.4 10 PDB header:circadian rhythm Chain: A: PDB Molecule:period circadian protein; PDBTitle: crystal structure of the pas repeat region of the2 drosophila clock protein period 23 c2r78D_ not modelled 99.3 15 PDB header:transferase Chain: D: PDB Molecule:sensor protein; PDBTitle: crystal structure of a domain of the sensory box sensor2 histidine kinase/response regulator from geobacter3 sulfurreducens 24 c3mfxA_ not modelled 99.3 13 PDB header:transcription Chain: A: PDB Molecule:sensory box/ggdef family protein; PDBTitle: crystal structure of the sensory box domain of the sensory-2 box/ggdef protein so_1695 from shewanella oneidensis,3 northeast structural genomics consortium target sor288b 25 c3mjqB_ not modelled 99.2 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the pas domain of q24qt8_deshy protein from2 desulfitobacterium hafniense. northeast structural genomics3 consortium target dhr85c. 26 c2pr6A_ not modelled 99.2 21 PDB header:flavoprotein, signaling protein Chain: A: PDB Molecule:blue-light photoreceptor; PDBTitle: structural basis for light-dependent signaling in the dimeric lov2 photosensor ytva (light structure) 27 c3mqoB_ not modelled 99.2 12 PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator, luxr family; PDBTitle: the crystal structure of the pas domain in complex with isopropanol of2 a transcriptional regulator in the luxr family from burkholderia3 thailandensis to 1.7a 28 c3caxA_ not modelled 99.2 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pf0695; PDBTitle: crystal structure of uncharacterized protein pf0695 29 c2v1bA_ not modelled 99.2 12 PDB header:transferase Chain: A: PDB Molecule:nph1-1; PDBTitle: n- and c-terminal helices of oat lov2 (404-546) are2 involved in light-induced signal transduction (room3 temperature (293k) light structure of lov2 (404-546)) 30 c3ewkA_ not modelled 99.2 13 PDB header:flavoprotein Chain: A: PDB Molecule:sensor protein; PDBTitle: structure of the redox sensor domain of methylococcus capsulatus2 (bath) mmos 31 c3oloB_ not modelled 99.2 12 PDB header:transferase Chain: B: PDB Molecule:two-component sensor histidine kinase; PDBTitle: crystal structure of a pas domain from two-component sensor histidine2 kinase 32 d1y28a_ not modelled 99.2 18 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Heme-binding PAS domain 33 d1p97a_ not modelled 99.1 12 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Hypoxia-inducible factor Hif2a, C-terminal domain 34 c3b33A_ not modelled 99.1 16 PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of the pas domain of nitrogen regulation protein2 nr(ii) from vibrio parahaemolyticus 35 c2l4rA_ not modelled 99.1 14 PDB header:transport protein Chain: A: PDB Molecule:potassium voltage-gated channel subfamily h member 2; PDBTitle: nmr solution structure of the n-terminal pas domain of herg 36 d1bywa_ not modelled 99.1 12 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Flavin-binding PAS domain 37 c3luqC_ not modelled 99.1 14 PDB header:transferase Chain: C: PDB Molecule:sensor protein; PDBTitle: the crystal structure of a pas domain from a sensory box2 histidine kinase regulator from geobacter sulfurreducens to3 2.5a 38 c1v9yA_ not modelled 99.0 15 PDB header:signaling protein Chain: A: PDB Molecule:heme pas sensor protein; PDBTitle: crystal structure of the heme pas sensor domain of ec dos (ferric2 form) 39 d1v9ya_ not modelled 99.0 15 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Heme-binding PAS domain 40 c3lyxA_ not modelled 99.0 17 PDB header:transcription Chain: A: PDB Molecule:sensory box/ggdef domain protein; PDBTitle: crystal structure of the pas domain of the protein cps_12912 from colwellia psychrerythraea. northeast structural3 genomics consortium target id csr222b 41 d1xj3a1 not modelled 99.0 17 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Heme-binding PAS domain 42 d1ll8a_ not modelled 99.0 9 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:N-terminal PAS domain of Pas kinase 43 c2gj3A_ not modelled 99.0 15 PDB header:transferase Chain: A: PDB Molecule:nitrogen fixation regulatory protein; PDBTitle: crystal structure of the fad-containing pas domain of the2 protein nifl from azotobacter vinelandii. 44 c2wkqA_ not modelled 99.0 14 PDB header:transferase, cell adhesion Chain: A: PDB Molecule:nph1-1, ras-related c3 botulinum toxin substrate PDBTitle: structure of a photoactivatable rac1 containing the lov22 c450a mutant 45 c2z6dB_ not modelled 99.0 10 PDB header:transferase Chain: B: PDB Molecule:phototropin-2; PDBTitle: crystal structure of lov1 domain of phototropin2 from2 arabidopsis thaliana 46 c3mxqC_ not modelled 99.0 16 PDB header:transferase Chain: C: PDB Molecule:sensor protein; PDBTitle: crystal structure of sensory box sensor histidine kinase from vibrio2 cholerae 47 c3mr0B_ not modelled 99.0 13 PDB header:transcription regulator Chain: B: PDB Molecule:sensory box histidine kinase/response regulator; PDBTitle: crystal structure of sensory box histidine kinase/response regulator2 from burkholderia thailandensis e264 48 c3f1oB_ not modelled 99.0 10 PDB header:transcription Chain: B: PDB Molecule:aryl hydrocarbon receptor nuclear translocator; PDBTitle: crystal structure of the high affinity heterodimer of hif22 alpha and arnt c-terminal pas domains, with an internally-3 bound artificial ligand 49 c2vlgD_ not modelled 99.0 11 PDB header:transferase Chain: D: PDB Molecule:sporulation kinase a; PDBTitle: kina pas-a domain, homodimer 50 d1n9la_ not modelled 99.0 14 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Flavin-binding PAS domain 51 c3kx0X_ not modelled 98.9 12 PDB header:signaling protein Chain: X: PDB Molecule:uncharacterized protein rv1364c/mt1410; PDBTitle: crystal structure of the pas domain of rv1364c 52 c3k3dA_ not modelled 98.9 14 PDB header:signaling protein Chain: A: PDB Molecule:protein rv1364c/mt1410; PDBTitle: the n-terminal pas domain crystal structure of rv1364c from2 mycobacterium tuberculosis at 2.3 angstrom 53 c3h9wA_ not modelled 98.9 6 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:diguanylate cyclase with pas/pac sensor; PDBTitle: crystal structure of the n-terminal domain of diguanylate cyclase with2 pas/pac sensor (maqu_2914) from marinobacter aquaeolei, northeast3 structural genomics consortium target mqr66c 54 c3eehA_ not modelled 98.9 14 PDB header:transferase Chain: A: PDB Molecule:putative light and redox sensing histidine kinase; PDBTitle: the crystal structure of the domain of the putative light and redox2 sensing histidine kinase from haloarcula marismortui 55 d1jnua_ not modelled 98.9 11 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Flavin-binding PAS domain 56 c2kdkA_ not modelled 98.8 10 PDB header:transcription regulator Chain: A: PDB Molecule:aryl hydrocarbon receptor nuclear translocator-like protein PDBTitle: structure of human circadian clock protein bmal2 c-terminal pas domain 57 c3fg8B_ not modelled 98.8 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein rha05790; PDBTitle: crystal structure of pas domain of rha05790 58 c2pdtD_ not modelled 98.7 12 PDB header:circadian clock protein Chain: D: PDB Molecule:vivid pas protein vvd; PDBTitle: 2.3 angstrom structure of phosphodiesterase treated vivid 59 c2jheB_ not modelled 98.6 9 PDB header:transcription Chain: B: PDB Molecule:transcription regulator tyrr; PDBTitle: n-terminal domain of tyrr transcription factor (residues 1 -2 190) 60 d1otda_ not modelled 98.5 13 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:PYP-like 61 d1oj5a_ not modelled 98.4 11 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:PAS domain of steroid receptor coactivator 1A, NCo-A1 62 c2qkpD_ not modelled 98.4 10 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of c-terminal domain of smu_1151c from streptococcus2 mutans 63 d1nwza_ not modelled 98.4 10 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:PYP-like 64 c3fc7B_ not modelled 98.4 14 PDB header:transferase Chain: B: PDB Molecule:htr-like protein; PDBTitle: the crystal structure of a domain of htr-like protein from haloarcula2 marismortui atcc 43049 65 d1xfna1 not modelled 98.4 11 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:PYP-like 66 c3icyB_ not modelled 98.4 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:sensor protein; PDBTitle: the crystal structure of sensory box histidine2 kinase/response regulator domain from chlorobium tepidum3 tls 67 c2o9bA_ not modelled 98.3 8 PDB header:transferase Chain: A: PDB Molecule:bacteriophytochrome; PDBTitle: crystal structure of bacteriophytochrome chromophore binding domain 68 d1mzua_ not modelled 98.3 8 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:PYP-like 69 c3njaC_ not modelled 98.2 12 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:probable ggdef family protein; PDBTitle: the crystal structure of the pas domain of a ggdef family protein from2 chromobacterium violaceum atcc 12472. 70 c2w0nA_ not modelled 98.2 13 PDB header:transferase Chain: A: PDB Molecule:sensor protein dcus; PDBTitle: plasticity of pas domain and potential role for signal2 transduction in the histidine-kinase dcus 71 c3a0rA_ not modelled 98.2 12 PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360) 72 c3cloC_ not modelled 98.1 8 PDB header:transcription regulator Chain: C: PDB Molecule:transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator containing a2 luxr dna binding domain (np_811094.1) from bacteroides3 thetaiotaomicron vpi-5482 at 2.04 a resolution 73 c2oolA_ not modelled 98.1 7 PDB header:signaling protein Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of the chromophore-binding domain of an unusual2 bacteriophytochrome rpbphp3 from r. palustris 74 c3a0vA_ not modelled 98.0 13 PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: pas domain of histidine kinase thka (tm1359) (semet,2 f486m/f489m) 75 c2veaA_ not modelled 97.7 7 PDB header:transferase Chain: A: PDB Molecule:phytochrome-like protein cph1; PDBTitle: the complete sensory module of the cyanobacterial2 phytochrome cph1 in the pr-state. 76 c2qv6D_ not modelled 97.2 17 PDB header:hydrolase Chain: D: PDB Molecule:gtp cyclohydrolase iii; PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions 77 d1azsa_ not modelled 95.0 13 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 78 c1cjkA_ not modelled 94.9 13 PDB header:lyase/lyase/signaling protein Chain: A: PDB Molecule:adenylate cyclase, type v; PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn 79 c1y10C_ not modelled 91.6 14 PDB header:lyase Chain: C: PDB Molecule:hypothetical protein rv1264/mt1302; PDBTitle: mycobacterial adenylyl cyclase rv1264, holoenzyme, inhibited state 80 c3c2wB_ not modelled 90.5 13 PDB header:signaling protein Chain: B: PDB Molecule:bacteriophytochrome; PDBTitle: crystal structure of the photosensory core domain of p.2 aeruginosa bacteriophytochrome pabphp in the pfr state 81 c1yk9A_ not modelled 89.7 12 PDB header:lyase Chain: A: PDB Molecule:adenylate cyclase; PDBTitle: crystal structure of a mutant form of the mycobacterial2 adenylyl cyclase rv1625c 82 c3uvjC_ not modelled 89.2 13 PDB header:lyase Chain: C: PDB Molecule:guanylate cyclase soluble subunit alpha-3; PDBTitle: crystal structure of the catalytic domain of the heterodimeric human2 soluble guanylate cyclase 1. 83 c2w01C_ not modelled 85.2 15 PDB header:lyase Chain: C: PDB Molecule:adenylate cyclase; PDBTitle: crystal structure of the guanylyl cyclase cya2 84 c3mr7B_ not modelled 84.5 9 PDB header:hydrolase Chain: B: PDB Molecule:adenylate/guanylate cyclase/hydrolase, alpha/beta fold PDBTitle: crystal structure of adenylate/guanylate cyclase/hydrolase from2 silicibacter pomeroyi 85 c1wc6B_ not modelled 83.7 15 PDB header:lyase Chain: B: PDB Molecule:adenylate cyclase; PDBTitle: soluble adenylyl cyclase cyac from s. platensis in complex2 with rp-atpalphas in presence of bicarbonate 86 d1wc1a_ not modelled 79.1 15 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 87 d2o9ca2 not modelled 75.0 10 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:BphP N-terminal domain-like 88 c1ybuA_ not modelled 68.8 16 PDB header:hydrolase Chain: A: PDB Molecule:lipj; PDBTitle: mycobacterium tuberculosis adenylyl cyclase rv1900c chd, in complex2 with a substrate analog. 89 c3et6A_ not modelled 67.9 13 PDB header:lyase Chain: A: PDB Molecule:soluble guanylyl cyclase beta; PDBTitle: the crystal structure of the catalytic domain of a eukaryotic2 guanylate cyclase 90 d1fx4a_ not modelled 66.2 15 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 91 d1fx2a_ not modelled 57.5 12 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 92 c3gqcB_ not modelled 43.8 22 PDB header:transferase/dna Chain: B: PDB Molecule:dna repair protein rev1; PDBTitle: structure of human rev1-dna-dntp ternary complex 93 c3pxpA_ not modelled 39.5 11 PDB header:transcription regulator Chain: A: PDB Molecule:helix-turn-helix domain protein; PDBTitle: crystal structure of a pas and dna binding domain containing protein2 (caur_2278) from chloroflexus aurantiacus j-10-fl at 2.30 a3 resolution 94 d2veaa3 not modelled 37.1 12 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:BphP N-terminal domain-like 95 d1azsb_ not modelled 35.9 11 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 96 c3onqB_ not modelled 33.3 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:regulator of polyketide synthase expression; PDBTitle: crystal structure of regulator of polyketide synthase expression2 bad_0249 from bifidobacterium adolescentis 97 c2wz1B_ not modelled 32.9 8 PDB header:lyase Chain: B: PDB Molecule:guanylate cyclase soluble subunit beta-1; PDBTitle: structure of the catalytic domain of human soluble2 guanylate cyclase 1 beta 3. 98 c2aq4A_ not modelled 29.1 26 PDB header:transferase Chain: A: PDB Molecule:dna repair protein rev1; PDBTitle: ternary complex of the catalytic core of rev1 with dna and dctp. 99 d3c2wa3 not modelled 23.7 13 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:BphP N-terminal domain-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0