Phyre 2 Results for P25516

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Email | l.a.kelley@imperial.ac.uk
Description | P25516
Date | Thu Jan 5 11:41:52 GMT 2012
Unique Job ID | b6ee1aed79cad8cc

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c2b3yB_
Top template information
PDB header:lyase Chain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1)
Confidence and coverage
Confidence: | 100.0% | Coverage: | 99%
878 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | S | S | T | L | R | E | A | S | K | D | T | L | Q | A | K | D | K | T | Y | H | Y | Y | S | L | P | L | A | A | K | S | L | G | D | I | T | R | L | P | K | S | L | K | V | L | L | E | N | L | L | R | W | Q | D | G | N | S | V | T | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | E | D | I | H | A | L | A | G | W | L | K | N | A | H | A | D | R | E | I | A | Y | R | P | A | R | V | L | M | Q | D | F | T | G | V | P | A | V | V | D | L | A | A | M | R | E | A | V | K | R | L | G | G | D | T | A | K | V | N | P | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | S | P | V | D | L | V | I | D | H | S | V | T | V | D | R | F | G | D | D | E | A | F | E | E | N | V | R | L | E | M | E | R | N | H | E | R | Y | V | F | L | K | W | G | K | Q | A | F | S | R | F | S | V | V | P | P | G | T | G | I | C
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | H | Q | V | N | L | E | Y | L | G | K | A | V | W | S | E | L | Q | D | G | E | W | I | A | Y | P | D | T | L | V | G | T | D | S | H | T | T | M | I | N | G | L | G | V | L | G | W | G | V | G | G | I | E | A | E | A | A | M | L | G | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | P | V | S | M | L | I | P | D | V | V | G | F | K | L | T | G | K | L | R | E | G | I | T | A | T | D | L | V | L | T | V | T | Q | M | L | R | K | H | G | V | V | G | K | F | V | E | F | Y | G | D | G | L | D | S | L | P | L | A | D | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | A | T | I | A | N | M | S | P | E | Y | G | A | T | C | G | F | F | P | I | D | A | V | T | L | D | Y | M | R | L | S | G | R | S | E | D | Q | V | E | L | V | E | K | Y | A | K | A | Q | G | M | W | R | N | P | G | D | E | P | I | F | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | S | T | L | E | L | D | M | N | D | V | E | A | S | L | A | G | P | K | R | P | Q | D | R | V | A | L | P | D | V | P | K | A | F | A | A | S | N | E | L | E | V | N | A | T | H | K | D | R | Q | P | V | D | Y | V | M | N | G | H | Q | Y
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  | ? |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | Q | L | P | D | G | A | V | V | I | A | A | I | T | S | C | T | N | T | S | N | P | S | V | L | M | A | A | G | L | L | A | K | K | A | V | T | L | G | L | K | R | Q | P | W | V | K | A | S | L | A | P | G | S | K | V | V | S | D | Y | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | A | K | A | K | L | T | P | Y | L | D | E | L | G | F | N | L | V | G | Y | G | C | T | T | C | I | G | N | S | G | P | L | P | D | P | I | E | T | A | I | K | K | S | D | L | T | V | G | A | V | L | S | G | N | R | N | F | E | G | R | I
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600
Sequence |  | H | P | L | V | K | T | N | W | L | A | S | P | P | L | V | V | A | Y | A | L | A | G | N | M | N | I | N | L | A | S | E | P | I | G | H | D | R | K | G | D | P | V | Y | L | K | D | I | W | P | S | A | Q | E | I | A | R | A | V | E | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660
Sequence |  | V | S | T | E | M | F | R | K | E | Y | A | E | V | F | E | G | T | A | E | W | K | G | I | N | V | T | R | S | D | T | Y | G | W | Q | E | D | S | T | Y | I | R | L | S | P | F | F | D | E | M | Q | A | T | P | A | P | V | E | D | I | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  | ? |  | ? | ? | ? |  | ? |  |  |  |  | ? |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? |  |  | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720
Sequence |  | G | A | R | I | L | A | M | L | G | D | S | V | T | T | D | H | I | S | P | A | G | S | I | K | P | D | S | P | A | G | R | Y | L | Q | G | R | G | V | E | R | K | D | F | N | S | Y | G | S | R | R | G | N | H | E | V | M | M | R | G | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780
Sequence |  | F | A | N | I | R | I | R | N | E | M | V | P | G | V | E | G | G | M | T | R | H | L | P | D | S | D | V | V | S | I | Y | D | A | A | M | R | Y | K | Q | E | Q | T | P | L | A | V | I | A | G | K | E | Y | G | S | G | S | S | R | D | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840
Sequence |  | A | A | K | G | P | R | L | L | G | I | R | V | V | I | A | E | S | F | E | R | I | H | R | S | N | L | I | G | M | G | I | L | P | L | E | F | P | Q | G | V | T | R | K | T | L | G | L | T | G | E | E | K | I | D | I | G | D | L | Q | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | .
Sequence |  | L | Q | P | G | A | T | V | P | V | T | L | T | R | A | D | G | S | Q | E | V | V | P | C | R | C | R | I | D | T | A | T | E | L | T | Y | Y | Q | N | D | G | I | L | H | Y | V | I | R | N | M | L | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c2b3yB_ |

### PDB 2b3y chain B

Region: 3 - 891
Aligned: 878
Modelled: 889
Confidence: 100.0%
Identity: 52%
PDB header:lyase
Chain: B: PDB Molecule:iron-responsive element binding protein 1;
PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1)

Phyre2
2 |
| c5acnA_ |

### PDB 5acn chain A

Region: 22 - 891
Aligned: 747
Modelled: 794
Confidence: 100.0%
Identity: 29%
PDB header:lyase(carbon-oxygen)
Chain: A: PDB Molecule:aconitase;
PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal

Phyre2
3 |
| d2b3ya2 |

### PDB 2b3y chain A domain 2

Region: 8 - 627
Aligned: 614
Modelled: 620
Confidence: 100.0%
Identity: 52%
Fold: Aconitase iron-sulfur domain
Superfamily: Aconitase iron-sulfur domain
Family: Aconitase iron-sulfur domain

Phyre2
4 |
| d1acoa2 |

### PDB 1aco chain A domain 2

Region: 22 - 618
Aligned: 512
Modelled: 556
Confidence: 100.0%
Identity: 29%
Fold: Aconitase iron-sulfur domain
Superfamily: Aconitase iron-sulfur domain
Family: Aconitase iron-sulfur domain

Phyre2
5 |
| d1l5ja3 |

### PDB 1l5j chain A domain 3

Region: 53 - 614
Aligned: 456
Modelled: 491
Confidence: 100.0%
Identity: 23%
Fold: Aconitase iron-sulfur domain
Superfamily: Aconitase iron-sulfur domain
Family: Aconitase iron-sulfur domain

Phyre2
6 |
| c1l5jB_ |

### PDB 1l5j chain B

Region: 51 - 607
Aligned: 456
Modelled: 493
Confidence: 100.0%
Identity: 22%
PDB header:lyase
Chain: B: PDB Molecule:aconitate hydratase 2;
PDBTitle: crystal structure of e. coli aconitase b.

Phyre2
7 |
| d2b3ya1 |

### PDB 2b3y chain A domain 1

Region: 628 - 891
Aligned: 259
Modelled: 264
Confidence: 100.0%
Identity: 54%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: LeuD/IlvD-like
Family: LeuD-like

Phyre2
8 |
| d1acoa1 |

### PDB 1aco chain A domain 1

Region: 631 - 887
Aligned: 222
Modelled: 240
Confidence: 100.0%
Identity: 28%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: LeuD/IlvD-like
Family: LeuD-like

Phyre2
9 |
| d1v7la_ |

### PDB 1v7l chain A

Region: 659 - 888
Aligned: 156
Modelled: 160
Confidence: 100.0%
Identity: 35%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: LeuD/IlvD-like
Family: LeuD-like

Phyre2
10 |
| c2pkpA_ |

### PDB 2pkp chain A

Region: 659 - 890
Aligned: 158
Modelled: 172
Confidence: 100.0%
Identity: 31%
PDB header:lyase
Chain: A: PDB Molecule:homoaconitase small subunit;
PDBTitle: crystal structure of 3-isopropylmalate dehydratase (leud)2 from methhanocaldococcus jannaschii dsm2661 (mj1271)

Phyre2
11 |
| d1l5ja2 |

### PDB 1l5j chain A domain 2

Region: 655 - 890
Aligned: 178
Modelled: 197
Confidence: 100.0%
Identity: 20%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: LeuD/IlvD-like
Family: LeuD-like

Phyre2
12 |
| c2hcuA_ |

### PDB 2hcu chain A

Region: 649 - 879
Aligned: 175
Modelled: 200
Confidence: 100.0%
Identity: 25%
PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: crystal structure of smu.1381 (or leud) from streptococcus2 mutans

Phyre2
13 |
| c3q3wB_ |

### PDB 3q3w chain B

Region: 659 - 879
Aligned: 166
Modelled: 191
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: B: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: isopropylmalate isomerase small subunit from campylobacter jejuni.

Phyre2
14 |
| c3h5jA_ |

### PDB 3h5j chain A

Region: 659 - 879
Aligned: 161
Modelled: 173
Confidence: 100.0%
Identity: 27%
PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: leud_1-168 small subunit of isopropylmalate isomerase (rv2987c) from2 mycobacterium tuberculosis

Phyre2
15 |
| d1cf1a1 |

### PDB 1cf1 chain A domain 1

Region: 790 - 818
Aligned: 29
Modelled: 29
Confidence: 71.8%
Identity: 14%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: E set domains
Family: Arrestin/Vps26-like

Phyre2
16 |
| d1g4ma1 |

### PDB 1g4m chain A domain 1

Region: 790 - 818
Aligned: 29
Modelled: 29
Confidence: 69.4%
Identity: 28%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: E set domains
Family: Arrestin/Vps26-like

Phyre2
17 |
| d2r4qa1 |

### PDB 2r4q chain A domain 1

Region: 429 - 462
Aligned: 31
Modelled: 34
Confidence: 63.9%
Identity: 35%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Fructose specific IIB subunit-like

Phyre2
18 |
| c3c52B_ |

### PDB 3c52 chain B

Region: 86 - 151
Aligned: 60
Modelled: 66
Confidence: 59.5%
Identity: 30%
PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor

Phyre2
19 |
| c2iswB_ |

### PDB 2isw chain B

Region: 86 - 151
Aligned: 60
Modelled: 66
Confidence: 54.4%
Identity: 28%
PDB header:lyase
Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase;
PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate

Phyre2
20 |
| d1t3va_ |

### PDB 1t3v chain A

Region: 733 - 825
Aligned: 89
Modelled: 93
Confidence: 43.3%
Identity: 11%
Fold: Ribonuclease H-like motif
Superfamily: Nitrogenase accessory factor-like
Family: MTH1175-like

Phyre2
21 |
22 |
23 |
24 |
25 |
26 |
27 |
28 |
29 |
30 |
31 |
32 |
33 |
34 |
35 |
36 |
37 |
38 |
39 |
40 |
41 |
42 |
43 |
44 |
45 |
46 |
47 |
48 |
49 |
50 |
51 |
52 |
53 |
54 |
55 |
56 |
57 |
58 |
59 |
60 |
61 |
62 |
63 |
64 |
65 |
66 |
67 |
68 |
69 |
70 |
71 |
72 |
73 |
74 |
75 |
76 |
77 |
78 |
79 |
80 |
81 |
82 |
83 |
84 |
85 |
86 |
87 |
88 |
89 |
90 |
91 |
92 |
93 |
94 |
95 |
96 |
97 |
98 |
99 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2b3yB_ |
|  | 100.0 | 52 | PDB header:lyase Chain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1)
2 | c5acnA_ |
|  | 100.0 | 29 | PDB header:lyase(carbon-oxygen) Chain: A: PDB Molecule:aconitase; PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal
3 | d2b3ya2 |
|  | 100.0 | 52 | Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain
4 | d1acoa2 |
|  | 100.0 | 29 | Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain
5 | d1l5ja3 |
|  | 100.0 | 23 | Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain
6 | c1l5jB_ |
|  | 100.0 | 22 | PDB header:lyase Chain: B: PDB Molecule:aconitate hydratase 2; PDBTitle: crystal structure of e. coli aconitase b.
7 | d2b3ya1 |
|  | 100.0 | 54 | Fold:The "swivelling" beta/beta/alpha domain Superfamily:LeuD/IlvD-like Family:LeuD-like
8 | d1acoa1 |
|  | 100.0 | 28 | Fold:The "swivelling" beta/beta/alpha domain Superfamily:LeuD/IlvD-like Family:LeuD-like
9 | d1v7la_ |
|  | 100.0 | 35 | Fold:The "swivelling" beta/beta/alpha domain Superfamily:LeuD/IlvD-like Family:LeuD-like
10 | c2pkpA_ |
|  | 100.0 | 31 | PDB header:lyase Chain: A: PDB Molecule:homoaconitase small subunit; PDBTitle: crystal structure of 3-isopropylmalate dehydratase (leud)2 from methhanocaldococcus jannaschii dsm2661 (mj1271)
11 | d1l5ja2 |
|  | 100.0 | 20 | Fold:The "swivelling" beta/beta/alpha domain Superfamily:LeuD/IlvD-like Family:LeuD-like
12 | c2hcuA_ |
|  | 100.0 | 25 | PDB header:lyase Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit; PDBTitle: crystal structure of smu.1381 (or leud) from streptococcus2 mutans
13 | c3q3wB_ |
|  | 100.0 | 23 | PDB header:transferase Chain: B: PDB Molecule:3-isopropylmalate dehydratase small subunit; PDBTitle: isopropylmalate isomerase small subunit from campylobacter jejuni.
14 | c3h5jA_ |
|  | 100.0 | 27 | PDB header:lyase Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit; PDBTitle: leud_1-168 small subunit of isopropylmalate isomerase (rv2987c) from2 mycobacterium tuberculosis
15 | d1cf1a1 |
|  | 71.8 | 14 | Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Arrestin/Vps26-like
16 | d1g4ma1 |
|  | 69.4 | 28 | Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Arrestin/Vps26-like
17 | d2r4qa1 |
|  | 63.9 | 35 | Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Fructose specific IIB subunit-like
18 | c3c52B_ |
|  | 59.5 | 30 | PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor
19 | c2iswB_ |
|  | 54.4 | 28 | PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate
20 | d1t3va_ |
|  | 43.3 | 11 | Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like
21 | d1rdua_ |
| not modelled | 40.8 | 15 | Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like
22 | c3elfA_ |
| not modelled | 40.2 | 24 | PDB header:lyase Chain: A: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase
23 | d1dosa_ |
| not modelled | 34.8 | 38 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase
24 | d2r48a1 |
| not modelled | 31.6 | 39 | Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Fructose specific IIB subunit-like
25 | d1p90a_ |
| not modelled | 29.5 | 16 | Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:Nitrogenase accessory factor
26 | d1o13a_ |
| not modelled | 26.4 | 13 | Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like
27 | c2gp4A_ |
| not modelled | 25.2 | 14 | PDB header:lyase Chain: A: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis
28 | c2yx6C_ |
| not modelled | 24.7 | 15 | PDB header:structural genomics, unknown function Chain: C: PDB Molecule:hypothetical protein ph0822; PDBTitle: crystal structure of ph0822
29 | d1o60a_ |
| not modelled | 23.7 | 16 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase
30 | c3bolB_ |
| not modelled | 23.7 | 21 | PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+
31 | c3qm3C_ |
| not modelled | 23.6 | 23 | PDB header:lyase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni
32 | c2wbrA_ |
| not modelled | 23.5 | 31 | PDB header:dna-binding protein Chain: A: PDB Molecule:gw182; PDBTitle: the rrm domain in gw182 proteins contributes to mirna-2 mediated gene silencing
33 | c3q94B_ |
| not modelled | 23.0 | 28 | PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'
34 | c3l2iB_ |
| not modelled | 22.7 | 15 | PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.85 angstrom crystal structure of the 3-dehydroquinate dehydratase2 (arod) from salmonella typhimurium lt2.
35 | d1gvfa_ |
| not modelled | 22.5 | 21 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase
36 | d1t0tv_ |
| not modelled | 22.3 | 23 | Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Chlorite dismutase-like
37 | d1rvga_ |
| not modelled | 21.4 | 29 | Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase
38 | c3iz5Q_ |
| not modelled | 19.9 | 22 | PDB header:ribosome Chain: Q: PDB Molecule:60s ribosomal protein l5 (l18p); PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
39 | c2rhbD_ |
| not modelled | 19.8 | 33 | PDB header:viral protein Chain: D: PDB Molecule:uridylate-specific endoribonuclease; PDBTitle: crystal structure of nsp15-h234a mutant- hexamer in2 asymmetric unit
40 | d3bofa2 |
| not modelled | 19.4 | 19 | Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase
41 | d1iuka_ |
| not modelled | 19.2 | 20 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain
42 | c2kyrA_ |
| not modelled | 19.1 | 24 | PDB header:transferase Chain: A: PDB Molecule:fructose-like phosphotransferase enzyme iib component 1; PDBTitle: solution structure of enzyme iib subunit of pts system from2 escherichia coli k12. northeast structural genomics consortium target3 er315/ontario center for structural proteomics target ec0544
43 | c2wfbA_ |
| not modelled | 18.7 | 19 | PDB header:biosynthetic protein Chain: A: PDB Molecule:putative uncharacterized protein orp; PDBTitle: high resolution structure of the apo form of the orange2 protein (orp) from desulfovibrio gigas
44 | d1vdha_ |
| not modelled | 18.7 | 18 | Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Chlorite dismutase-like
45 | d2aioa1 |
| not modelled | 18.4 | 19 | Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Zn metallo-beta-lactamase
46 | d1eo1a_ |
| not modelled | 17.4 | 22 | Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like
47 | c3c3jA_ |
| not modelled | 16.7 | 10 | PDB header:isomerase Chain: A: PDB Molecule:putative tagatose-6-phosphate ketose/aldose isomerase; PDBTitle: crystal structure of tagatose-6-phosphate ketose/aldose isomerase from2 escherichia coli
48 | c3dmyA_ |
| not modelled | 16.3 | 25 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein fdra; PDBTitle: crystal structure of a predicated acyl-coa synthetase from e.coli
49 | d1eg7a_ |
| not modelled | 16.1 | 19 | Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like
50 | c3l4gI_ |
| not modelled | 16.0 | 33 | PDB header:ligase Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase
51 | d2ghra1 |
| not modelled | 16.0 | 19 | Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:HTS-like
52 | c2yrvA_ |
| not modelled | 15.8 | 24 | PDB header:transcription Chain: A: PDB Molecule:at-rich interactive domain-containing protein 4a; PDBTitle: solution structure of the rbb1nt domain of human2 rb(retinoblastoma)-binding protein 1
53 | c2oxlA_ |
| not modelled | 15.2 | 14 | PDB header:gene regulation Chain: A: PDB Molecule:hypothetical protein ymgb; PDBTitle: structure and function of the e. coli protein ymgb: a protein critical2 for biofilm formation and acid resistance
54 | d2ac7a1 |
| not modelled | 15.1 | 17 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
55 | d2gp4a2 |
| not modelled | 14.9 | 12 | Fold:IlvD/EDD N-terminal domain-like Superfamily:IlvD/EDD N-terminal domain-like Family:lvD/EDD N-terminal domain-like
56 | d2ieaa3 |
| not modelled | 14.6 | 29 | Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Transketolase C-terminal domain-like
57 | d2zdra1 |
| not modelled | 14.0 | 23 | Fold:beta-clip Superfamily:AFP III-like domain Family:AFP III-like domain
58 | d1jjca_ |
| not modelled | 13.9 | 21 | Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
59 | c2vxhF_ |
| not modelled | 13.7 | 9 | PDB header:oxidoreductase Chain: F: PDB Molecule:chlorite dismutase; PDBTitle: the crystal structure of chlorite dismutase: a detox enzyme2 producing molecular oxygen
60 | c3cf4A_ |
| not modelled | 13.6 | 16 | PDB header:oxidoreductase Chain: A: PDB Molecule:acetyl-coa decarboxylase/synthase alpha subunit; PDBTitle: structure of the codh component of the m. barkeri acds complex
61 | c3qpbB_ |
| not modelled | 13.5 | 21 | PDB header:transferase Chain: B: PDB Molecule:uridine phosphorylase; PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily
62 | c2o8vA_ |
| not modelled | 13.1 | 20 | PDB header:oxidoreductase Chain: A: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: paps reductase in a covalent complex with thioredoxin c35a
63 | c3mwbA_ |
| not modelled | 13.1 | 15 | PDB header:lyase Chain: A: PDB Molecule:prephenate dehydratase; PDBTitle: the crystal structure of prephenate dehydratase in complex with l-phe2 from arthrobacter aurescens to 2.0a
64 | c2jz2A_ |
| not modelled | 13.0 | 11 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ssl0352 protein; PDBTitle: solution nmr structure of ssl0352 protein from synechocystis sp. pcc2 6803. northeast structural genomics consortium target sgr42
65 | d1k6ka_ |
| not modelled | 12.9 | 25 | Fold:Double Clp-N motif Superfamily:Double Clp-N motif Family:Double Clp-N motif
66 | c2r2dC_ |
| not modelled | 12.5 | 21 | PDB header:hydrolase Chain: C: PDB Molecule:zn-dependent hydrolases; PDBTitle: structure of a quorum-quenching lactonase (aiib) from agrobacterium2 tumefaciens
67 | c2w9mB_ |
| not modelled | 12.5 | 35 | PDB header:dna replication Chain: B: PDB Molecule:polymerase x; PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans
68 | c1pt1B_ |
| not modelled | 12.5 | 19 | PDB header:lyase Chain: B: PDB Molecule:aspartate 1-decarboxylase; PDBTitle: unprocessed pyruvoyl dependent aspartate decarboxylase with histidine2 11 mutated to alanine
69 | c2ebbA_ |
| not modelled | 12.4 | 18 | PDB header:lyase Chain: A: PDB Molecule:pterin-4-alpha-carbinolamine dehydratase; PDBTitle: crystal structure of pterin-4-alpha-carbinolamine2 dehydratase (pterin carbinolamine dehydratase) from3 geobacillus kaustophilus hta426
70 | d1vjta1 |
| not modelled | 12.3 | 28 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like
71 | d1ppya_ |
| not modelled | 11.6 | 19 | Fold:Double psi beta-barrel Superfamily:ADC-like Family:Pyruvoyl dependent aspartate decarboxylase, ADC
72 | d1vhwa_ |
| not modelled | 11.5 | 20 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
73 | c1z34A_ |
| not modelled | 11.5 | 18 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of trichomonas vaginalis purine nucleoside2 phosphorylase complexed with 2-fluoro-2'-deoxyadenosine
74 | c3nn4C_ |
| not modelled | 11.3 | 9 | PDB header:oxidoreductase Chain: C: PDB Molecule:chlorite dismutase; PDBTitle: structure of chlorite dismutase from candidatus nitrospira defluvii2 r173k mutant
75 | c2gacD_ |
| not modelled | 11.2 | 30 | PDB header:hydrolase Chain: D: PDB Molecule:glycosylasparaginase; PDBTitle: t152c mutant glycosylasparaginase from flavobacterium2 meningosepticum
76 | d1lt7a_ |
| not modelled | 10.9 | 20 | Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase
77 | d1p9ea_ |
| not modelled | 10.9 | 19 | Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Methyl parathion hydrolase
78 | c1p9eA_ |
| not modelled | 10.9 | 19 | PDB header:hydrolase Chain: A: PDB Molecule:methyl parathion hydrolase; PDBTitle: crystal structure analysis of methyl parathion hydrolase from2 pseudomonas sp wbc-3
79 | d1ybfa_ |
| not modelled | 10.9 | 20 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
80 | c2kmfA_ |
| not modelled | 10.7 | 28 | PDB header:photosynthesis Chain: A: PDB Molecule:photosystem ii 11 kda protein; PDBTitle: solution structure of psb27 from cyanobacterial photosystem2 ii
81 | c1b70A_ |
| not modelled | 10.7 | 21 | PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase; PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine
82 | c3do6B_ |
| not modelled | 10.6 | 18 | PDB header:ligase Chain: B: PDB Molecule:formate--tetrahydrofolate ligase; PDBTitle: crystal structure of putative formyltetrahydrofolate2 synthetase (tm1766) from thermotoga maritima at 1.85 a3 resolution
83 | d1hyua4 |
| not modelled | 10.6 | 23 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like
84 | d1uf2c1 |
| not modelled | 10.4 | 21 | Fold:A virus capsid protein alpha-helical domain Superfamily:A virus capsid protein alpha-helical domain Family:Phytoreovirus capsid
85 | d1je0a_ |
| not modelled | 10.4 | 20 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
86 | c3fz5C_ |
| not modelled | 10.3 | 14 | PDB header:isomerase Chain: C: PDB Molecule:possible 2-hydroxychromene-2-carboxylate isomerase; PDBTitle: crystal structure of possible 2-hydroxychromene-2-carboxylate2 isomerase from rhodobacter sphaeroides
87 | d1umya_ |
| not modelled | 10.3 | 20 | Fold:TIM beta/alpha-barrel Superfamily:Homocysteine S-methyltransferase Family:Homocysteine S-methyltransferase
88 | c2nu8D_ |
| not modelled | 10.2 | 18 | PDB header:ligase Chain: D: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha; PDBTitle: c123at mutant of e. coli succinyl-coa synthetase
89 | c1p0yA_ |
| not modelled | 10.1 | 18 | PDB header:transferase Chain: A: PDB Molecule:ribulose-1,5 bisphosphate carboxylase/oxygenase PDBTitle: crystal structure of the set domain of lsmt bound to2 melysine and adohcy
90 | c3r2nC_ |
| not modelled | 9.9 | 26 | PDB header:hydrolase Chain: C: PDB Molecule:cytidine deaminase; PDBTitle: crystal structure of cytidine deaminase from mycobacterium leprae
91 | d3c8ya1 |
| not modelled | 9.8 | 17 | Fold:Fe-only hydrogenase Superfamily:Fe-only hydrogenase Family:Fe-only hydrogenase
92 | d2pt0a1 |
| not modelled | 9.8 | 13 | Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Myo-inositol hexaphosphate phosphohydrolase (phytase) PhyA
93 | c2v4oB_ |
| not modelled | 9.6 | 29 | PDB header:hydrolase Chain: B: PDB Molecule:multifunctional protein sur e; PDBTitle: crystal structure of salmonella typhimurium sure at 2.752 angstrom resolution in monoclinic form
94 | c3bjeA_ |
| not modelled | 9.1 | 19 | PDB header:transferase Chain: A: PDB Molecule:nucleoside phosphorylase, putative; PDBTitle: crystal structure of trypanosoma brucei nucleoside phosphorylase shows2 uridine phosphorylase activity
95 | d1th7a1 |
| not modelled | 9.1 | 23 | Fold:Sm-like fold Superfamily:Sm-like ribonucleoproteins Family:Sm motif of small nuclear ribonucleoproteins, SNRNP
96 | c3oqhB_ |
| not modelled | 8.9 | 20 | PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein yvmc; PDBTitle: crystal structure of b. licheniformis cdps yvmc-blic
97 | c2phjA_ |
| not modelled | 8.9 | 31 | PDB header:hydrolase Chain: A: PDB Molecule:5'-nucleotidase sure; PDBTitle: crystal structure of sure protein from aquifex aeolicus
98 | c3bl5E_ |
| not modelled | 8.9 | 19 | PDB header:hydrolase Chain: E: PDB Molecule:queuosine biosynthesis protein quec; PDBTitle: crystal structure of quec from bacillus subtilis: an enzyme2 involved in preq1 biosynthesis
99 | d1pvda3 |
| not modelled | 8.7 | 23 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction |

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0