Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	T	Y	L	I	G	D	V	H	G	C	Y	D	E	L	I	A	L	L	H	K	V	E	F	T	P	G	K	D	T	L	W	L	T	G	D	L	V	A	R	G	P	G	S	L	D	V	L	R	Y	V	K	S	L	G	D	S	V	R
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	V	L	G	N	H	D	L	H	L	L	A	V	F	A	G	I	S	R	N	K	P	K	D	R	L	T	P	L	L	E	A	P	D	A	D	E	L	L	N	W	L	R	R	Q	P	L	L	Q	I	D	E	E	K	K	L	V	M	A	H
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	G	I	T	P	Q	W	D	L	Q	T	A	K	E	C	A	R	D	V	E	A	V	L	S	S	D	S	Y	P	F	F	L	D	A	M	Y	G	D	M	P	N	N	W	S	P	E	L	R	G	L	G	R	L	R	F	I	T	N	A	F
Secondary structure
SS confidence
Disorder																																										?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	R	M	R	F	C	F	P	N	G	Q	L	D	M	Y	S	K	E	S	P	E	E	A	P	A	P	L	K	P	W	F	A	I	P	G	P	V	A	E	E	Y	S	I	A	F	G	H	W	A	S	L	E	G	K	G	T	P	E	G	I
Secondary structure
SS confidence
Disorder																		?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence		Y	A	L	D	T	G	C	C	W	G	G	T	L	T	C	L	R	W	E	D	K	Q	Y	F	V	Q	P	S	N	R	H	K	D	L	G	E	A	A	A	S
Secondary structure
SS confidence
Disorder																														?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2dfj chain A Region: 2 - 268 Aligned: 267 Modelled: 267 Confidence: 100.0% Identity: 100% PDB header:hydrolase Chain: A: PDB Molecule:diadenosinetetraphosphatase; PDBTitle: crystal structure of the diadenosine tetraphosphate2 hydrolase from shigella flexneri 2a Phyre2 PDB 2qjc chain A Region: 2 - 268 Aligned: 206 Modelled: 216 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:diadenosine tetraphosphatase, putative; PDBTitle: crystal structure of a putative diadenosine tetraphosphatase Phyre2 PDB 2zbm chain A Region: 2 - 266 Aligned: 235 Modelled: 237 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:protein-tyrosine-phosphatase; PDBTitle: crystal structure of i115m mutant cold-active protein2 tyrosine phosphatase Phyre2 PDB 1g5b chain A Region: 2 - 260 Aligned: 196 Modelled: 199 Confidence: 100.0% Identity: 24% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Protein serine/threonine phosphatase Phyre2 PDB 1jk7 chain A Region: 3 - 272 Aligned: 231 Modelled: 233 Confidence: 100.0% Identity: 18% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Protein serine/threonine phosphatase Phyre2 PDB 3c5w chain C domain 1 Region: 3 - 268 Aligned: 227 Modelled: 233 Confidence: 100.0% Identity: 17% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Protein serine/threonine phosphatase Phyre2 PDB 1s70 chain A Region: 3 - 280 Aligned: 239 Modelled: 241 Confidence: 100.0% Identity: 17% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Protein serine/threonine phosphatase Phyre2 PDB 2jog chain A Region: 3 - 273 Aligned: 239 Modelled: 244 Confidence: 99.9% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha PDBTitle: structure of the calcineurin-nfat complex Phyre2 PDB 1s95 chain A Region: 3 - 280 Aligned: 239 Modelled: 240 Confidence: 99.9% Identity: 18% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Protein serine/threonine phosphatase Phyre2 PDB 1aui chain A Region: 3 - 267 Aligned: 233 Modelled: 238 Confidence: 99.9% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:serine/threonine phosphatase 2b; PDBTitle: human calcineurin heterodimer Phyre2 PDB 1aui chain A Region: 3 - 267 Aligned: 233 Modelled: 238 Confidence: 99.9% Identity: 17% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Protein serine/threonine phosphatase Phyre2 PDB 2p6b chain C Region: 3 - 279 Aligned: 245 Modelled: 250 Confidence: 99.9% Identity: 17% PDB header:hydrolase/hydrolase regulator Chain: C: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha PDBTitle: crystal structure of human calcineurin in complex with2 pvivit peptide Phyre2 PDB 2p6b chain A domain 1 Region: 3 - 279 Aligned: 245 Modelled: 250 Confidence: 99.9% Identity: 17% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Protein serine/threonine phosphatase Phyre2 PDB 3icf chain B Region: 2 - 262 Aligned: 221 Modelled: 224 Confidence: 99.9% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:serine/threonine-protein phosphatase t; PDBTitle: structure of protein serine/threonine phosphatase from saccharomyces2 cerevisiae with similarity to human phosphatase pp5 Phyre2 PDB 1wao chain 4 Region: 2 - 276 Aligned: 236 Modelled: 237 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure Phyre2 PDB 1uf3 chain A Region: 2 - 263 Aligned: 213 Modelled: 223 Confidence: 99.9% Identity: 12% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: TT1561-like Phyre2 PDB 1nnw chain A Region: 2 - 258 Aligned: 186 Modelled: 187 Confidence: 99.8% Identity: 17% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: Phosphoesterase-related Phyre2 PDB 3qfn chain A Region: 1 - 267 Aligned: 196 Modelled: 198 Confidence: 99.8% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate Phyre2 PDB 1su1 chain A Region: 1 - 267 Aligned: 157 Modelled: 159 Confidence: 99.7% Identity: 23% Fold: Metallo-dependent phosphatases Superfamily: Metallo-dependent phosphatases Family: YfcE-like Phyre2 PDB 1su1 chain A Region: 1 - 267 Aligned: 157 Modelled: 159 Confidence: 99.7% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yfce; PDBTitle: structural and biochemical characterization of yfce, a2 phosphoesterase from e. coli Phyre2 1 c2dfjA_ 2 c2qjcA_ 3 c2zbmA_ 4 d1g5ba_ 5 d1jk7a_ 6 d3c5wc1 7 d1s70a_ 8 c2jogA_ 9 d1s95a_ 10 c1auiA_ 11 d1auia_ 12 c2p6bC_ 13 d2p6ba1 14 c3icfB_ 15 c1wao4_ 16 d1uf3a_ 17 d1nnwa_ 18 c3qfnA_ 19 d1su1a_ 20 c1su1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2dfjA_ 100.0 100 PDB header:hydrolase Chain: A: PDB Molecule:diadenosinetetraphosphatase; PDBTitle: crystal structure of the diadenosine tetraphosphate2 hydrolase from shigella flexneri 2a 2 c2qjcA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:diadenosine tetraphosphatase, putative; PDBTitle: crystal structure of a putative diadenosine tetraphosphatase 3 c2zbmA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:protein-tyrosine-phosphatase; PDBTitle: crystal structure of i115m mutant cold-active protein2 tyrosine phosphatase 4 d1g5ba_ 100.0 24 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 5 d1jk7a_ 100.0 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 6 d3c5wc1 100.0 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 7 d1s70a_ 100.0 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 8 c2jogA_ 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha PDBTitle: structure of the calcineurin-nfat complex 9 d1s95a_ 99.9 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 10 c1auiA_ 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:serine/threonine phosphatase 2b; PDBTitle: human calcineurin heterodimer 11 d1auia_ 99.9 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 12 c2p6bC_ 99.9 17 PDB header:hydrolase/hydrolase regulator Chain: C: PDB Molecule:calmodulin-dependent calcineurin a subunit alpha PDBTitle: crystal structure of human calcineurin in complex with2 pvivit peptide 13 d2p6ba1 99.9 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 14 c3icfB_ 99.9 16 PDB header:hydrolase Chain: B: PDB Molecule:serine/threonine-protein phosphatase t; PDBTitle: structure of protein serine/threonine phosphatase from saccharomyces2 cerevisiae with similarity to human phosphatase pp5 15 c1wao4_ 99.9 18 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 16 d1uf3a_ 99.9 12 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 17 d1nnwa_ 99.8 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Phosphoesterase-related 18 c3qfnA_ 99.8 23 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of streptococcal asymmetric ap4a hydrolase and2 phosphodiesterase spr1479/saph in complex with inorganic phosphate 19 d1su1a_ 99.7 23 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 20 c1su1A_ 99.7 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein yfce; PDBTitle: structural and biochemical characterization of yfce, a2 phosphoesterase from e. coli 21 c3rqzC_ not modelled 99.7 22 PDB header:hydrolase Chain: C: PDB Molecule:metallophosphoesterase; PDBTitle: crystal structure of metallophosphoesterase from sphaerobacter2 thermophilus 22 d2yvta1 not modelled 99.5 15 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 23 c1s3mA_ not modelled 99.5 21 PDB header:phosphodiesterase Chain: A: PDB Molecule:hypothetical protein mj0936; PDBTitle: structural and functional characterization of a novel2 archaeal phosphodiesterase 24 d1s3la_ not modelled 99.5 21 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 25 d2a22a1 not modelled 99.4 16 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 26 c2kknA_ not modelled 99.3 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution nmr structure of themotoga maritima protein tm1076:2 northeast structural genomics consortium target vt57 27 d1z2wa1 not modelled 99.3 19 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 28 d3ck2a1 not modelled 99.3 22 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 29 d1xm7a_ not modelled 99.2 34 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Hypothetical protein aq 1666 30 c3av0A_ not modelled 98.8 29 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11-rad50 bound to atp s 31 d1ii7a_ not modelled 98.8 27 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DNA double-strand break repair nuclease 32 c3auzA_ not modelled 98.7 29 PDB header:recombination Chain: A: PDB Molecule:dna double-strand break repair protein mre11; PDBTitle: crystal structure of mre11 with manganese 33 c3rl4A_ not modelled 98.5 28 PDB header:hydrolase Chain: A: PDB Molecule:metallophosphoesterase mpped2; PDBTitle: rat metallophosphodiesterase mpped2 g252h mutant 34 c2hy1A_ not modelled 98.4 17 PDB header:hydrolase Chain: A: PDB Molecule:rv0805; PDBTitle: crystal structure of rv0805 35 d2hy1a1 not modelled 98.4 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 36 c2q8uA_ not modelled 98.4 23 PDB header:hydrolase Chain: A: PDB Molecule:exonuclease, putative; PDBTitle: crystal structure of mre11 from thermotoga maritima msb8 (tm1635) at2 2.20 a resolution 37 d3d03a1 not modelled 98.4 25 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 38 c3ib7A_ not modelled 98.4 32 PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 39 c2xmoB_ not modelled 98.4 34 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 40 c3qg5D_ not modelled 98.4 30 PDB header:hydrolase Chain: D: PDB Molecule:mre11; PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair 41 d2nxfa1 not modelled 98.3 23 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:ADPRibase-Mn-like 42 c3t1iC_ not modelled 98.2 27 PDB header:hydrolase Chain: C: PDB Molecule:double-strand break repair protein mre11a; PDBTitle: crystal structure of human mre11: understanding tumorigenic mutations 43 d2z1aa2 not modelled 98.0 22 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 44 c2z1aA_ not modelled 97.8 20 PDB header:hydrolase Chain: A: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase precursor from thermus2 thermophilus hb8 45 c3qfkA_ not modelled 97.8 20 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: 2.05 angstrom crystal structure of putative 5'-nucleotidase from2 staphylococcus aureus in complex with alpha-ketoglutarate 46 d1usha2 not modelled 97.8 23 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 47 d1xzwa2 not modelled 97.7 20 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 48 c3ivdA_ not modelled 97.7 14 PDB header:hydrolase Chain: A: PDB Molecule:nucleotidase; PDBTitle: putative 5'-nucleotidase (c4898) from escherichia coli in2 complex with uridine 49 c1oidA_ not modelled 97.7 22 PDB header:hydrolase Chain: A: PDB Molecule:protein usha; PDBTitle: 5'-nucleotidase (e. coli) with an engineered disulfide2 bridge (s228c, p513c) 50 d1utea_ not modelled 97.6 25 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 51 c1qhwA_ not modelled 97.6 23 PDB header:hydrolase Chain: A: PDB Molecule:protein (purple acid phosphatase); PDBTitle: purple acid phosphatase from rat bone 52 d1qhwa_ not modelled 97.6 23 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 53 c3zu0A_ not modelled 97.6 18 PDB header:hydrolase Chain: A: PDB Molecule:nad nucleotidase; PDBTitle: structure of haemophilus influenzae nad nucleotidase (nadn) 54 d1t71a_ not modelled 97.5 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DR1281-like 55 d2z06a1 not modelled 97.4 26 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TTHA0625-like 56 d2qfra2 not modelled 97.3 23 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Purple acid phosphatase-like 57 c3jyfB_ not modelled 97.3 23 PDB header:hydrolase Chain: B: PDB Molecule:2',3'-cyclic nucleotide 2'-phosphodiesterase/3'- PDBTitle: the crystal structure of a 2,3-cyclic nucleotide 2-2 phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor3 protein from klebsiella pneumoniae subsp. pneumoniae mgh 78578 58 c3gveB_ not modelled 97.3 24 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:yfkn protein; PDBTitle: crystal structure of calcineurin-like phosphoesterase yfkn from2 bacillus subtilis 59 d1t70a_ not modelled 97.2 32 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:DR1281-like 60 d3c9fa2 not modelled 97.0 18 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 61 c3c9fB_ not modelled 96.8 23 PDB header:hydrolase Chain: B: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase from candida albicans sc5314 62 c1kbpB_ not modelled 95.8 25 PDB header:hydrolase (phosphoric monoester) Chain: B: PDB Molecule:purple acid phosphatase; PDBTitle: kidney bean purple acid phosphatase 63 c2wdfA_ not modelled 95.6 23 PDB header:hydrolase Chain: A: PDB Molecule:sulfur oxidation protein soxb; PDBTitle: termus thermophilus sulfate thiohydrolase soxb 64 c1xzwB_ not modelled 95.3 21 PDB header:hydrolase Chain: B: PDB Molecule:purple acid phosphatase; PDBTitle: sweet potato purple acid phosphatase/phosphate complex 65 c3floG_ not modelled 86.7 13 PDB header:transferase Chain: G: PDB Molecule:dna polymerase alpha subunit b; PDBTitle: crystal structure of the carboxyl-terminal domain of yeast2 dna polymerase alpha in complex with its b subunit 66 c3e0jG_ not modelled 60.2 27 PDB header:transferase Chain: G: PDB Molecule:dna polymerase subunit delta-2; PDBTitle: x-ray structure of the complex of regulatory subunits of2 human dna polymerase delta 67 d1gg4a1 not modelled 43.0 16 Fold:MurD-like peptide ligases, peptide-binding domain Superfamily:MurD-like peptide ligases, peptide-binding domain Family:MurCDEF C-terminal domain 68 c1y8aA_ not modelled 34.1 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein af1437; PDBTitle: structure of gene product af1437 from archaeoglobus fulgidus 69 d1qupa2 not modelled 33.2 20 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 70 d1ecfa1 not modelled 31.3 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 71 d1ux6a1 not modelled 31.2 13 Fold:Concanavalin A-like lectins/glucanases Superfamily:Concanavalin A-like lectins/glucanases Family:Thrombospondin C-terminal domain 72 c2rogA_ not modelled 30.1 19 PDB header:metal binding protein Chain: A: PDB Molecule:heavy metal binding protein; PDBTitle: solution structure of thermus thermophilus hb8 ttha17182 protein in living e. coli cells 73 d1gph11 not modelled 29.4 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 74 c2issF_ not modelled 25.7 34 PDB header:lyase, transferase Chain: F: PDB Molecule:glutamine amidotransferase subunit pdxt; PDBTitle: structure of the plp synthase holoenzyme from thermotoga maritima 75 d1o57a2 not modelled 20.3 8 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 76 d1okga1 not modelled 18.5 19 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 77 d1nbwa2 not modelled 17.2 15 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ATPase domain of dehydratase reactivase alpha subunit 78 d1ka9h_ not modelled 16.3 32 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 79 c1gph1_ not modelled 16.1 17 PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis 80 c1m6yA_ not modelled 14.3 24 PDB header:transferase Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw; PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah 81 c1urhA_ not modelled 13.9 8 PDB header:transferase Chain: A: PDB Molecule:3-mercaptopyruvate sulfurtransferase; PDBTitle: the "rhodanese" fold and catalytic mechanism of2 3-mercaptopyruvate sulfotransferases: crystal structure3 of ssea from escherichia coli 82 c2b3yB_ not modelled 13.5 30 PDB header:lyase Chain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1) 83 c1o57A_ not modelled 13.4 8 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 84 d1fe0a_ not modelled 13.2 17 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 85 c3mjdA_ not modelled 13.0 14 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis. 86 d1yt8a4 not modelled 12.2 17 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 87 c1ecjB_ not modelled 12.1 17 PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer 88 c3n9iA_ not modelled 11.8 20 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from yersinia pestis2 co92 89 c2gamA_ not modelled 11.6 27 PDB header:transferase Chain: A: PDB Molecule:beta-1,6-n-acetylglucosaminyltransferase; PDBTitle: x-ray crystal structure of murine leukocyte-type core 2 b1,2 6-n-acetylglucosaminyltransferase (c2gnt-l) in complex3 with galb1,3galnac 90 d2b3ya1 not modelled 11.5 31 Fold:The "swivelling" beta/beta/alpha domain Superfamily:LeuD/IlvD-like Family:LeuD-like 91 c3elyA_ not modelled 10.4 67 PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: wesselsbron virus methyltransferase in complex with adohcy 92 d1ylea1 not modelled 10.2 24 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:AstA-like 93 c2nz2A_ not modelled 9.9 26 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline 94 c2zufA_ not modelled 9.7 15 PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii arginyl-trna2 synthetase complexed with trna(arg) 95 c2ov6A_ not modelled 9.4 38 PDB header:hydrolase Chain: A: PDB Molecule:v-type atp synthase subunit f; PDBTitle: the nmr structure of subunit f of the methanogenic a1ao atp synthase2 and its interaction with the nucleotide-binding subunit b 96 c3rjtA_ not modelled 9.2 21 PDB header:hydrolase Chain: A: PDB Molecule:lipolytic protein g-d-s-l family; PDBTitle: crystal structure of lipolytic protein g-d-s-l family from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446 97 c2przB_ not modelled 9.1 9 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp 98 c2l8bA_ not modelled 9.1 17 PDB header:hydrolase Chain: A: PDB Molecule:protein trai; PDBTitle: trai (381-569) 99 c2wnsB_ not modelled 9.1 19 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0