Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	D	K	L	R	S	R	I	V	H	L	G	P	S	L	L	S	V	P	V	K	L	T	P	F	A	L	K	R	Q	V	L	E	Q	V	L	S	W	Q	F	R	Q	A	L	D	D	G	E	L	E	F	L	E	G	R	W	L	S	I
Secondary structure
SS confidence
Disorder		?											?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	V	R	D	I	D	L	Q	W	F	T	S	V	V	N	G	K	L	V	V	S	Q	N	A	Q	A	D	V	S	F	S	A	D	A	S	D	L	L	M	I	A	A	R	K	Q	D	P	D	T	L	F	F	Q	R	R	L	V	I	E	G
Secondary structure
SS confidence
Disorder																	?					?																										?	?	?	?			?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.
Sequence		D	T	E	L	G	L	Y	V	K	N	L	M	D	A	I	E	L	E	Q	M	P	K	A	L	R	M	M	L	L	Q	L	A	D	F	V	E	A	G	M	K	T	A	P	E	T	K	Q	T	S	V	G	E	P	C
Secondary structure
SS confidence
Disorder																																						?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ikt chain A Region: 28 - 135 Aligned: 106 Modelled: 108 Confidence: 99.5% Identity: 17% Fold: SCP-like Superfamily: SCP-like Family: Sterol carrier protein, SCP Phyre2 PDB 1c44 chain A Region: 25 - 133 Aligned: 106 Modelled: 109 Confidence: 99.5% Identity: 26% Fold: SCP-like Superfamily: SCP-like Family: Sterol carrier protein, SCP Phyre2 PDB 3bn8 chain A Region: 57 - 135 Aligned: 78 Modelled: 79 Confidence: 99.4% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:putative sterol carrier protein 2; PDBTitle: crystal structure of a putative sterol carrier protein type 2 (af1534)2 from archaeoglobus fulgidus dsm 4304 at 2.11 a resolution Phyre2 PDB 3bkr chain A Region: 55 - 134 Aligned: 80 Modelled: 80 Confidence: 99.4% Identity: 19% PDB header:lipid binding protein Chain: A: PDB Molecule:sterol carrier protein-2 like-3; PDBTitle: crystal structure of sterol carrier protein-2 like-3 (scp2-2 l3) from aedes aegypti Phyre2 PDB 3bdq chain B Region: 55 - 132 Aligned: 78 Modelled: 78 Confidence: 99.4% Identity: 18% PDB header:lipid transport Chain: B: PDB Molecule:sterol carrier protein 2-like 2; PDBTitle: room tempreture crystal structure of sterol carrier protein-2 2 like-2 Phyre2 PDB 1pz4 chain A Region: 55 - 135 Aligned: 80 Modelled: 81 Confidence: 99.3% Identity: 16% Fold: SCP-like Superfamily: SCP-like Family: Sterol carrier protein, SCP Phyre2 PDB 2cfu chain A domain 1 Region: 47 - 138 Aligned: 92 Modelled: 92 Confidence: 99.2% Identity: 16% Fold: SCP-like Superfamily: SCP-like Family: Alkylsulfatase C-terminal domain-like Phyre2 PDB 1wfr chain A Region: 63 - 135 Aligned: 73 Modelled: 73 Confidence: 99.0% Identity: 14% Fold: SCP-like Superfamily: SCP-like Family: Sterol carrier protein, SCP Phyre2 PDB 2cfu chain A Region: 46 - 138 Aligned: 93 Modelled: 93 Confidence: 98.2% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid. Phyre2 PDB 2i00 chain A domain 1 Region: 54 - 132 Aligned: 77 Modelled: 79 Confidence: 96.6% Identity: 14% Fold: SCP-like Superfamily: SCP-like Family: EF1021 C-terminal domain-like Phyre2 PDB 2ozg chain A domain 1 Region: 57 - 132 Aligned: 72 Modelled: 76 Confidence: 96.2% Identity: 22% Fold: SCP-like Superfamily: SCP-like Family: EF1021 C-terminal domain-like Phyre2 PDB 2hv2 chain A domain 1 Region: 57 - 132 Aligned: 74 Modelled: 76 Confidence: 95.5% Identity: 18% Fold: SCP-like Superfamily: SCP-like Family: EF1021 C-terminal domain-like Phyre2 PDB 2ozg chain A Region: 57 - 132 Aligned: 72 Modelled: 76 Confidence: 95.2% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:gcn5-related n-acetyltransferase; PDBTitle: crystal structure of gcn5-related n-acetyltransferase (yp_325469.1)2 from anabaena variabilis atcc 29413 at 2.00 a resolution Phyre2 PDB 2i00 chain D Region: 54 - 131 Aligned: 76 Modelled: 78 Confidence: 92.9% Identity: 14% PDB header:transferase Chain: D: PDB Molecule:acetyltransferase, gnat family; PDBTitle: crystal structure of acetyltransferase (gnat family) from enterococcus2 faecalis Phyre2 PDB 2hv2 chain D Region: 57 - 132 Aligned: 72 Modelled: 76 Confidence: 92.5% Identity: 18% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of conserved protein of unknown function from2 enterococcus faecalis v583 at 2.4 a resolution, probable n-3 acyltransferase Phyre2 PDB 3r1k chain A Region: 57 - 132 Aligned: 72 Modelled: 76 Confidence: 79.7% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:enhanced intracellular survival protein; PDBTitle: crystal structure of acetyltransferase eis from mycobacterium2 tuberculosis h37rv in complex with coa and an acetamide moiety Phyre2 PDB 3n7z chain D Region: 58 - 132 Aligned: 70 Modelled: 75 Confidence: 78.2% Identity: 14% PDB header:transferase Chain: D: PDB Molecule:acetyltransferase, gnat family; PDBTitle: crystal structure of acetyltransferase from bacillus anthracis Phyre2 PDB 3d33 chain B Region: 53 - 91 Aligned: 32 Modelled: 37 Confidence: 9.2% Identity: 25% PDB header:unknown function Chain: B: PDB Molecule:domain of unknown function with an immunoglobulin-like PDBTitle: crystal structure of a duf3244 family protein with an immunoglobulin-2 like beta-sandwich fold (bvu_0276) from bacteroides vulgatus atcc3 8482 at 1.70 a resolution Phyre2 PDB 1y76 chain A domain 1 Region: 2 - 39 Aligned: 38 Modelled: 38 Confidence: 8.5% Identity: 24% Fold: L27 domain Superfamily: L27 domain Family: L27 domain Phyre2 PDB 1xn8 chain A Region: 118 - 154 Aligned: 37 Modelled: 37 Confidence: 7.5% Identity: 27% Fold: Hypothetical protein YqbG Superfamily: Hypothetical protein YqbG Family: Hypothetical protein YqbG Phyre2 1 d1ikta_ 2 d1c44a_ 3 c3bn8A_ 4 c3bkrA_ 5 c3bdqB_ 6 d1pz4a_ 7 d2cfua1 8 d1wfra_ 9 c2cfuA_ 10 d2i00a1 11 d2ozga1 12 d2hv2a1 13 c2ozgA_ 14 c2i00D_ 15 c2hv2D_ 16 c3r1kA_ 17 c3n7zD_ 18 c3d33B_ 19 d1y76a1 20 d1xn8a_ 21 22 23

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1ikta_ 99.5 17 Fold:SCP-like Superfamily:SCP-like Family:Sterol carrier protein, SCP 2 d1c44a_ 99.5 26 Fold:SCP-like Superfamily:SCP-like Family:Sterol carrier protein, SCP 3 c3bn8A_ 99.4 12 PDB header:transport protein Chain: A: PDB Molecule:putative sterol carrier protein 2; PDBTitle: crystal structure of a putative sterol carrier protein type 2 (af1534)2 from archaeoglobus fulgidus dsm 4304 at 2.11 a resolution 4 c3bkrA_ 99.4 19 PDB header:lipid binding protein Chain: A: PDB Molecule:sterol carrier protein-2 like-3; PDBTitle: crystal structure of sterol carrier protein-2 like-3 (scp2-2 l3) from aedes aegypti 5 c3bdqB_ 99.4 18 PDB header:lipid transport Chain: B: PDB Molecule:sterol carrier protein 2-like 2; PDBTitle: room tempreture crystal structure of sterol carrier protein-2 2 like-2 6 d1pz4a_ 99.3 16 Fold:SCP-like Superfamily:SCP-like Family:Sterol carrier protein, SCP 7 d2cfua1 99.2 16 Fold:SCP-like Superfamily:SCP-like Family:Alkylsulfatase C-terminal domain-like 8 d1wfra_ 99.0 14 Fold:SCP-like Superfamily:SCP-like Family:Sterol carrier protein, SCP 9 c2cfuA_ 98.2 16 PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid. 10 d2i00a1 96.6 14 Fold:SCP-like Superfamily:SCP-like Family:EF1021 C-terminal domain-like 11 d2ozga1 96.2 22 Fold:SCP-like Superfamily:SCP-like Family:EF1021 C-terminal domain-like 12 d2hv2a1 95.5 18 Fold:SCP-like Superfamily:SCP-like Family:EF1021 C-terminal domain-like 13 c2ozgA_ 95.2 22 PDB header:transferase Chain: A: PDB Molecule:gcn5-related n-acetyltransferase; PDBTitle: crystal structure of gcn5-related n-acetyltransferase (yp_325469.1)2 from anabaena variabilis atcc 29413 at 2.00 a resolution 14 c2i00D_ 92.9 14 PDB header:transferase Chain: D: PDB Molecule:acetyltransferase, gnat family; PDBTitle: crystal structure of acetyltransferase (gnat family) from enterococcus2 faecalis 15 c2hv2D_ 92.5 18 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of conserved protein of unknown function from2 enterococcus faecalis v583 at 2.4 a resolution, probable n-3 acyltransferase 16 c3r1kA_ 79.7 18 PDB header:transferase Chain: A: PDB Molecule:enhanced intracellular survival protein; PDBTitle: crystal structure of acetyltransferase eis from mycobacterium2 tuberculosis h37rv in complex with coa and an acetamide moiety 17 c3n7zD_ 78.2 14 PDB header:transferase Chain: D: PDB Molecule:acetyltransferase, gnat family; PDBTitle: crystal structure of acetyltransferase from bacillus anthracis 18 c3d33B_ 9.2 25 PDB header:unknown function Chain: B: PDB Molecule:domain of unknown function with an immunoglobulin-like PDBTitle: crystal structure of a duf3244 family protein with an immunoglobulin-2 like beta-sandwich fold (bvu_0276) from bacteroides vulgatus atcc3 8482 at 1.70 a resolution 19 d1y76a1 8.5 24 Fold:L27 domain Superfamily:L27 domain Family:L27 domain 20 d1xn8a_ 7.5 27 Fold:Hypothetical protein YqbG Superfamily:Hypothetical protein YqbG Family:Hypothetical protein YqbG 21 c2vd2A_ not modelled 6.5 23 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase; PDBTitle: the crystal structure of hisg from b. subtilis 22 c3fgxA_ not modelled 5.9 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:rbstp2171; PDBTitle: structure of uncharacterised protein rbstp2171 from bacillus2 stearothermophilus 23 c2nsfA_ not modelled 5.3 12 PDB header:isomerase Chain: A: PDB Molecule:hypothetical protein cgl3021; PDBTitle: crystal structure of the mycothiol-dependent maleylpyruvate isomerase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0