Phyre 2 Results for P0AF12

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Email | l.a.kelley@imperial.ac.uk
Description | P0AF12
Date | Thu Jan 5 11:24:52 GMT 2012
Unique Job ID | ac3929887efe5264

Summary |

Top model
Image coloured by rainbow N → C terminus
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Model (left) based on template c3bl6A_
Top template information
PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of staphylococcus aureus 5'-2 methylthioadenosine/s-adenosylhomocysteine nucleosidase in3 complex with formycin a
Confidence and coverage
Confidence: | 100.0% | Coverage: | 99%
229 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | K | I | G | I | I | G | A | M | E | E | E | V | T | L | L | R | D | K | I | E | N | R | Q | T | I | S | L | G | G | C | E | I | Y | T | G | Q | L | N | G | T | E | V | A | L | L | K | S | G | I | G | K | V | A | A | A | L | G | A | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | L | L | L | E | H | C | K | P | D | V | I | I | N | T | G | S | A | G | G | L | A | P | T | L | K | V | G | D | I | V | V | S | D | E | A | R | Y | H | D | A | D | V | T | A | F | G | Y | E | Y | G | Q | L | P | G | C | P | A | G | F | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | A | D | D | K | L | I | A | A | A | E | A | C | I | A | E | L | N | L | N | A | V | R | G | L | I | V | S | G | D | A | F | I | N | G | S | V | G | L | A | K | I | R | H | N | F | P | Q | A | I | A | V | E | M | E | A | T | A | I | A | H
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | .
Sequence |  | V | C | H | N | F | N | V | P | F | V | V | V | R | A | I | S | D | V | A | D | Q | Q | S | H | L | S | F | D | E | F | L | A | V | A | A | K | Q | S | S | L | M | V | E | S | L | V | Q | K | L | A | H | G
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c3bl6A_ |

### PDB 3bl6 chain A

Region: 1 - 229
Aligned: 229
Modelled: 229
Confidence: 100.0%
Identity: 55%
PDB header:hydrolase
Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase/s-
PDBTitle: crystal structure of staphylococcus aureus 5'-2 methylthioadenosine/s-adenosylhomocysteine nucleosidase in3 complex with formycin a

Phyre2
2 |
| c1zosE_ |

### PDB 1zos chain E

Region: 1 - 229
Aligned: 229
Modelled: 229
Confidence: 100.0%
Identity: 41%
PDB header:hydrolase
Chain: E: PDB Molecule:5'-methylthioadenosine / s-adenosylhomocysteine
PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma

Phyre2
3 |
| d1jysa_ |

### PDB 1jys chain A

Region: 1 - 230
Aligned: 226
Modelled: 230
Confidence: 100.0%
Identity: 100%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
4 |
| c3eeiA_ |

### PDB 3eei chain A

Region: 1 - 229
Aligned: 229
Modelled: 229
Confidence: 100.0%
Identity: 49%
PDB header:hydrolase
Chain: A: PDB Molecule:5-methylthioadenosine nucleosidase/s-
PDBTitle: crystal structure of 5'-methylthioadenosine/s-2 adenosylhomocysteine nucleosidase from neisseria3 meningitidis in complex with methylthio-immucillin-a

Phyre2
5 |
| c3dp9A_ |

### PDB 3dp9 chain A

Region: 2 - 229
Aligned: 228
Modelled: 228
Confidence: 100.0%
Identity: 61%
PDB header:hydrolase
Chain: A: PDB Molecule:mta/sah nucleosidase;
PDBTitle: crystal structure of vibrio cholerae 5'-methylthioadenosine/s-adenosyl2 homocysteine nucleosidase (mtan) complexed with butylthio-dadme-3 immucillin a

Phyre2
6 |
| c3nm5B_ |

### PDB 3nm5 chain B

Region: 2 - 229
Aligned: 227
Modelled: 228
Confidence: 100.0%
Identity: 35%
PDB header:hydrolase
Chain: B: PDB Molecule:mta/sah nucleosidase;
PDBTitle: helicobacter pylori mtan complexed with formycin a

Phyre2
7 |
| c2h8gA_ |

### PDB 2h8g chain A

Region: 2 - 230
Aligned: 216
Modelled: 229
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase;
PDBTitle: 5'-methylthioadenosine nucleosidase from arabidopsis2 thaliana

Phyre2
8 |
| c3bsfB_ |

### PDB 3bsf chain B

Region: 2 - 230
Aligned: 216
Modelled: 229
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: B: PDB Molecule:at4g34840;
PDBTitle: crystal structure of the mta/sah nucleosidase

Phyre2
9 |
| c1z34A_ |

### PDB 1z34 chain A

Region: 2 - 221
Aligned: 213
Modelled: 215
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:purine nucleoside phosphorylase;
PDBTitle: crystal structure of trichomonas vaginalis purine nucleoside2 phosphorylase complexed with 2-fluoro-2'-deoxyadenosine

Phyre2
10 |
| d1rxya_ |

### PDB 1rxy chain A

Region: 2 - 229
Aligned: 218
Modelled: 228
Confidence: 100.0%
Identity: 16%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
11 |
| d1je0a_ |

### PDB 1je0 chain A

Region: 2 - 218
Aligned: 211
Modelled: 217
Confidence: 100.0%
Identity: 21%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
12 |
| d1vhwa_ |

### PDB 1vhw chain A

Region: 2 - 226
Aligned: 218
Modelled: 220
Confidence: 100.0%
Identity: 18%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
13 |
| c1nw4C_ |

### PDB 1nw4 chain C

Region: 2 - 229
Aligned: 220
Modelled: 223
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: C: PDB Molecule:uridine phosphorylase, putative;
PDBTitle: crystal structure of plasmodium falciparum purine nucleoside2 phosphorylase in complex with immh and sulfate

Phyre2
14 |
| d1odka_ |

### PDB 1odk chain A

Region: 2 - 225
Aligned: 213
Modelled: 218
Confidence: 100.0%
Identity: 22%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
15 |
| d1q1ga_ |

### PDB 1q1g chain A

Region: 2 - 229
Aligned: 220
Modelled: 228
Confidence: 100.0%
Identity: 19%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
16 |
| d2ac7a1 |

### PDB 2ac7 chain A domain 1

Region: 2 - 214
Aligned: 206
Modelled: 213
Confidence: 100.0%
Identity: 19%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
17 |
| d1k9sa_ |

### PDB 1k9s chain A

Region: 2 - 226
Aligned: 218
Modelled: 225
Confidence: 100.0%
Identity: 18%
Fold: Phosphorylase/hydrolase-like
Superfamily: Purine and uridine phosphorylases
Family: Purine and uridine phosphorylases

Phyre2
18 |
| c3mb8A_ |

### PDB 3mb8 chain A

Region: 2 - 231
Aligned: 222
Modelled: 230
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:purine nucleoside phosphorylase;
PDBTitle: crystal structure of purine nucleoside phosphorylase from toxoplasma2 gondii in complex with immucillin-h

Phyre2
19 |
| c3tl6B_ |

### PDB 3tl6 chain B

Region: 2 - 218
Aligned: 202
Modelled: 217
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: B: PDB Molecule:purine nucleoside phosphorylase;
PDBTitle: crystal structure of purine nucleoside phosphorylase from entamoeba2 histolytica

Phyre2
20 |
| c3qpbB_ |

### PDB 3qpb chain B

Region: 2 - 228
Aligned: 219
Modelled: 227
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: B: PDB Molecule:uridine phosphorylase;
PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c3bl6A_ |
|  | 100.0 | 55 | PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of staphylococcus aureus 5'-2 methylthioadenosine/s-adenosylhomocysteine nucleosidase in3 complex with formycin a
2 | c1zosE_ |
|  | 100.0 | 41 | PDB header:hydrolase Chain: E: PDB Molecule:5'-methylthioadenosine / s-adenosylhomocysteine PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma
3 | d1jysa_ |
|  | 100.0 | 100 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
4 | c3eeiA_ |
|  | 100.0 | 49 | PDB header:hydrolase Chain: A: PDB Molecule:5-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of 5'-methylthioadenosine/s-2 adenosylhomocysteine nucleosidase from neisseria3 meningitidis in complex with methylthio-immucillin-a
5 | c3dp9A_ |
|  | 100.0 | 61 | PDB header:hydrolase Chain: A: PDB Molecule:mta/sah nucleosidase; PDBTitle: crystal structure of vibrio cholerae 5'-methylthioadenosine/s-adenosyl2 homocysteine nucleosidase (mtan) complexed with butylthio-dadme-3 immucillin a
6 | c3nm5B_ |
|  | 100.0 | 35 | PDB header:hydrolase Chain: B: PDB Molecule:mta/sah nucleosidase; PDBTitle: helicobacter pylori mtan complexed with formycin a
7 | c2h8gA_ |
|  | 100.0 | 24 | PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase; PDBTitle: 5'-methylthioadenosine nucleosidase from arabidopsis2 thaliana
8 | c3bsfB_ |
|  | 100.0 | 23 | PDB header:hydrolase Chain: B: PDB Molecule:at4g34840; PDBTitle: crystal structure of the mta/sah nucleosidase
9 | c1z34A_ |
|  | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of trichomonas vaginalis purine nucleoside2 phosphorylase complexed with 2-fluoro-2'-deoxyadenosine
10 | d1rxya_ |
|  | 100.0 | 16 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
11 | d1je0a_ |
|  | 100.0 | 21 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
12 | d1vhwa_ |
|  | 100.0 | 18 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
13 | c1nw4C_ |
|  | 100.0 | 19 | PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase, putative; PDBTitle: crystal structure of plasmodium falciparum purine nucleoside2 phosphorylase in complex with immh and sulfate
14 | d1odka_ |
|  | 100.0 | 22 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
15 | d1q1ga_ |
|  | 100.0 | 19 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
16 | d2ac7a1 |
|  | 100.0 | 19 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
17 | d1k9sa_ |
|  | 100.0 | 18 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
18 | c3mb8A_ |
|  | 100.0 | 18 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from toxoplasma2 gondii in complex with immucillin-h
19 | c3tl6B_ |
|  | 100.0 | 27 | PDB header:transferase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from entamoeba2 histolytica
20 | c3qpbB_ |
|  | 100.0 | 19 | PDB header:transferase Chain: B: PDB Molecule:uridine phosphorylase; PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily
21 | d1ybfa_ |
| not modelled | 100.0 | 16 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
22 | d1t8sa_ |
| not modelled | 100.0 | 19 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
23 | d1v4na_ |
| not modelled | 100.0 | 17 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
24 | c3khsB_ |
| not modelled | 100.0 | 19 | PDB header:hydrolase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of grouper iridovirus purine nucleoside2 phosphorylase
25 | c2xrfA_ |
| not modelled | 100.0 | 16 | PDB header:transferase Chain: A: PDB Molecule:uridine phosphorylase 2; PDBTitle: crystal structure of human uridine phosphorylase 2
26 | c1wtaA_ |
| not modelled | 100.0 | 16 | PDB header:transferase Chain: A: PDB Molecule:5'-methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-deoxy-5'-methylthioadenosine from aeropyrum2 pernix (r32 form)
27 | c3ozbF_ |
| not modelled | 100.0 | 14 | PDB header:transferase Chain: F: PDB Molecule:methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-methylthioinosine phosphorylase from2 psedomonas aeruginosa in complex with hypoxanthine
28 | c1tcvB_ |
| not modelled | 100.0 | 18 | PDB header:transferase Chain: B: PDB Molecule:purine-nucleoside phosphorylase; PDBTitle: crystal structure of the purine nucleoside phosphorylase2 from schistosoma mansoni in complex with non-detergent3 sulfobetaine 195 and acetate
29 | d1cb0a_ |
| not modelled | 100.0 | 16 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
30 | c3eufC_ |
| not modelled | 100.0 | 18 | PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase 1; PDBTitle: crystal structure of bau-bound human uridine phosphorylase 1
31 | d1vmka_ |
| not modelled | 100.0 | 14 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
32 | c3bjeA_ |
| not modelled | 100.0 | 16 | PDB header:transferase Chain: A: PDB Molecule:nucleoside phosphorylase, putative; PDBTitle: crystal structure of trypanosoma brucei nucleoside phosphorylase shows2 uridine phosphorylase activity
33 | c2p4sA_ |
| not modelled | 100.0 | 16 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: structure of purine nucleoside phosphorylase from anopheles gambiae in2 complex with dadme-immh
34 | c3la8A_ |
| not modelled | 100.0 | 15 | PDB header:transferase Chain: A: PDB Molecule:putative purine nucleoside phosphorylase; PDBTitle: the crystal structure of smu.1229 from streptococcus mutans ua159
35 | c1yr3A_ |
| not modelled | 100.0 | 18 | PDB header:transferase Chain: A: PDB Molecule:xanthosine phosphorylase; PDBTitle: escherichia coli purine nucleoside phosphorylase ii, the2 product of the xapa gene
36 | d3bgsa1 |
| not modelled | 100.0 | 17 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
37 | d1g2oa_ |
| not modelled | 99.9 | 13 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
38 | c3ggsA_ |
| not modelled | 99.9 | 19 | PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: human purine nucleoside phosphorylase double mutant e201q,n243d2 complexed with 2-fluoro-2'-deoxyadenosine
39 | d3pnpa_ |
| not modelled | 99.9 | 16 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
40 | d1qe5a_ |
| not modelled | 99.9 | 16 | Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases
41 | d1a2za_ |
| not modelled | 60.9 | 24 | Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
42 | c3giuA_ |
| not modelled | 50.7 | 19 | PDB header:hydrolase Chain: A: PDB Molecule:pyrrolidone-carboxylate peptidase; PDBTitle: 1.25 angstrom crystal structure of pyrrolidone-carboxylate peptidase2 (pcp) from staphylococcus aureus
43 | c3lacA_ |
| not modelled | 39.8 | 17 | PDB header:hydrolase Chain: A: PDB Molecule:pyrrolidone-carboxylate peptidase; PDBTitle: crystal structure of bacillus anthracis pyrrolidone-carboxylate2 peptidase, pcp
44 | d1iofa_ |
| not modelled | 35.0 | 24 | Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
45 | d1auga_ |
| not modelled | 22.7 | 17 | Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
46 | c2ywjA_ |
| not modelled | 20.5 | 21 | PDB header:transferase Chain: A: PDB Molecule:glutamine amidotransferase subunit pdxt; PDBTitle: crystal structure of uncharacterized conserved protein from2 methanocaldococcus jannaschii
47 | d1vb5a_ |
| not modelled | 16.6 | 33 | Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like
48 | d2nv0a1 |
| not modelled | 15.6 | 18 | Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT)
49 | d1t9ka_ |
| not modelled | 15.2 | 28 | Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like
50 | c2equA_ |
| not modelled | 14.8 | 30 | PDB header:protein binding Chain: A: PDB Molecule:phd finger protein 20-like 1; PDBTitle: solution structure of the tudor domain of phd finger2 protein 20-like 1
51 | c2yvkA_ |
| not modelled | 14.7 | 28 | PDB header:isomerase Chain: A: PDB Molecule:methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of 5-methylthioribose 1-phosphate2 isomerase product complex from bacillus subtilis
52 | d2a0ua1 |
| not modelled | 14.1 | 17 | Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like
53 | d1fdra2 |
| not modelled | 13.9 | 10 | Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain Family:Reductases
54 | d1t5oa_ |
| not modelled | 12.8 | 28 | Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like
55 | c1yt5A_ |
| not modelled | 12.2 | 22 | PDB header:transferase Chain: A: PDB Molecule:inorganic polyphosphate/atp-nad kinase; PDBTitle: crystal structure of nad kinase from thermotoga maritima
56 | c3cwcB_ |
| not modelled | 12.1 | 14 | PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2
57 | d1txga2 |
| not modelled | 11.1 | 50 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
58 | d2f1ka2 |
| not modelled | 10.2 | 63 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
59 | c1tvmA_ |
| not modelled | 9.9 | 8 | PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system
60 | c3a11D_ |
| not modelled | 9.4 | 17 | PDB header:isomerase Chain: D: PDB Molecule:translation initiation factor eif-2b, delta PDBTitle: crystal structure of ribose-1,5-bisphosphate isomerase from2 thermococcus kodakaraensis kod1
61 | d1jfla1 |
| not modelled | 9.3 | 42 | Fold:ATC-like Superfamily:Aspartate/glutamate racemase Family:Aspartate/glutamate racemase
62 | c1w2wJ_ |
| not modelled | 9.1 | 26 | PDB header:isomerase Chain: J: PDB Molecule:5-methylthioribose-1-phosphate isomerase; PDBTitle: crystal structure of yeast ypr118w, a methylthioribose-1-2 phosphate isomerase related to regulatory eif2b subunits
63 | c2pjkA_ |
| not modelled | 8.7 | 17 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:178aa long hypothetical molybdenum cofactor PDBTitle: structure of hypothetical molybdenum cofactor biosynthesis2 protein b from sulfolobus tokodaii
64 | d1eo1a_ |
| not modelled | 8.7 | 10 | Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like
65 | d1vola1 |
| not modelled | 8.4 | 15 | Fold:Cyclin-like Superfamily:Cyclin-like Family:Transcription factor IIB (TFIIB), core domain
66 | c2qneA_ |
| not modelled | 7.9 | 22 | PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase (zp_00558420.1) from2 desulfitobacterium hafniense y51 at 2.30 a resolution
67 | d1cqxa3 |
| not modelled | 7.7 | 18 | Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain Family:Flavohemoglobin, C-terminal domain
68 | d1gkub3 |
| not modelled | 7.7 | 13 | Fold:Prokaryotic type I DNA topoisomerase Superfamily:Prokaryotic type I DNA topoisomerase Family:Prokaryotic type I DNA topoisomerase
69 | c3peiA_ |
| not modelled | 7.7 | 27 | PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis
70 | d2bm8a1 |
| not modelled | 7.6 | 22 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:CmcI-like
71 | c2wfbA_ |
| not modelled | 7.3 | 10 | PDB header:biosynthetic protein Chain: A: PDB Molecule:putative uncharacterized protein orp; PDBTitle: high resolution structure of the apo form of the orange2 protein (orp) from desulfovibrio gigas
72 | d1gvha3 |
| not modelled | 7.2 | 16 | Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain Family:Flavohemoglobin, C-terminal domain
73 | d1dxya2 |
| not modelled | 7.2 | 29 | Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain
74 | d1iu8a_ |
| not modelled | 7.1 | 25 | Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
75 | d1o6ca_ |
| not modelled | 6.8 | 17 | Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:UDP-N-acetylglucosamine 2-epimerase
76 | d2fug61 |
| not modelled | 6.6 | 17 | Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nq06-like
77 | d1sqsa_ |
| not modelled | 6.5 | 11 | Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Hypothetical protein SP1951
78 | d1rdua_ |
| not modelled | 6.4 | 8 | Fold:Ribonuclease H-like motif Superfamily:Nitrogenase accessory factor-like Family:MTH1175-like
79 | d1l5xa_ |
| not modelled | 6.3 | 12 | Fold:SurE-like Superfamily:SurE-like Family:SurE-like
80 | d1ks9a2 |
| not modelled | 6.0 | 50 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
81 | d1a8pa2 |
| not modelled | 5.9 | 10 | Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain Family:Reductases
82 | c2f1kD_ |
| not modelled | 5.9 | 63 | PDB header:oxidoreductase Chain: D: PDB Molecule:prephenate dehydrogenase; PDBTitle: crystal structure of synechocystis arogenate dehydrogenase
83 | d1wd5a_ |
| not modelled | 5.8 | 18 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
84 | d1mv8a2 |
| not modelled | 5.8 | 50 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
85 | c1olsB_ |
| not modelled | 5.8 | 11 | PDB header:oxidoreductase Chain: B: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit; PDBTitle: roles of his291-alpha and his146-beta' in the reductive2 acylation reaction catalyzed by human branched-chain3 alpha-ketoacid dehydrogenase
86 | d1j0aa_ |
| not modelled | 5.7 | 11 | Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes
87 | d1a5za1 |
| not modelled | 5.7 | 75 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like
88 | d1gv0a1 |
| not modelled | 5.6 | 75 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like
89 | d1pvda2 |
| not modelled | 5.4 | 15 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
90 | d1zpda2 |
| not modelled | 5.4 | 18 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase Pyr module
91 | d1ojua1 |
| not modelled | 5.3 | 63 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like
92 | c3snrA_ |
| not modelled | 5.3 | 22 | PDB header:transport protein Chain: A: PDB Molecule:extracellular ligand-binding receptor; PDBTitle: rpd_1889 protein, an extracellular ligand-binding receptor from2 rhodopseudomonas palustris.
93 | c3ecsD_ |
| not modelled | 5.3 | 26 | PDB header:translation Chain: D: PDB Molecule:translation initiation factor eif-2b subunit PDBTitle: crystal structure of human eif2b alpha
94 | c3fysA_ |
| not modelled | 5.2 | 29 | PDB header:fatty acid-binding protein Chain: A: PDB Molecule:protein degv; PDBTitle: crystal structure of degv, a fatty acid binding protein2 from bacillus subtilis
95 | c2gf2B_ |
| not modelled | 5.1 | 50 | PDB header:oxidoreductase Chain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase; PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase
96 | d2bfdb1 |
| not modelled | 5.1 | 11 | Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Branched-chain alpha-keto acid dehydrogenase Pyr module

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0