Phyre 2 Results for P39187

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Email | l.a.kelley@imperial.ac.uk
Description | P39187
Date | Thu Jan 5 11:58:25 GMT 2012
Unique Job ID | a9ebe462ba25bd39

Summary |

Top model
Image coloured by rainbow N → C terminus
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Model (left) based on template d1st9a_
Top template information
Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
Confidence and coverage
Confidence: | 98.6% | Coverage: | 73%
135 residues ( 73% of your sequence) have been modelled with 98.6% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

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Sequence |  | M | T | L | R | K | I | L | A | L | T | C | L | L | L | P | M | M | A | S | A | H | Q | F | E | T | G | Q | R | V | P | P | I | G | I | T | D | R | G | E | L | V | L | D | K | D | Q | F | S | Y | K | T | W | N | S | A | Q | L | V | G | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | V | R | V | L | Q | H | I | A | G | R | T | S | A | K | E | K | N | A | T | L | I | E | A | I | K | S | A | K | L | P | H | D | R | Y | Q | T | T | T | I | V | N | T | D | D | A | I | P | G | S | G | M | F | V | R | S | S | L | E | S | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  | ? |  |  |  |  |  |  |  |  |  |  | ? |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | K | K | L | Y | P | W | S | Q | F | I | V | D | S | N | G | V | A | L | G | A | W | Q | L | D | E | E | S | S | A | V | V | V | L | D | K | D | G | R | V | Q | W | A | K | D | G | A | L | T | P | E | E | V | Q | Q | V | M | D | L | L | Q
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  | ? | ? | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | .
Sequence |  | K | L | L | K
Secondary structure |  |  |  |  |
SS confidence |  |  |  |  |
Disorder |  |  |  | ? | ?
Disorder confidence |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1st9a_ |

### PDB 1st9 chain A

Region: 26 - 180
Aligned: 135
Modelled: 151
Confidence: 98.6%
Identity: 18%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2
2 |
| c3kh7A_ |

### PDB 3kh7 chain A

Region: 23 - 183
Aligned: 140
Modelled: 144
Confidence: 98.4%
Identity: 15%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbe;
PDBTitle: crystal structure of the periplasmic soluble domain of reduced ccmg2 from pseudomonas aeruginosa

Phyre2
3 |
| c2hyxA_ |

### PDB 2hyx chain A

Region: 20 - 184
Aligned: 152
Modelled: 165
Confidence: 98.3%
Identity: 16%
PDB header:unknown function
Chain: A: PDB Molecule:protein dipz;
PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis

Phyre2
4 |
| c3hdcA_ |

### PDB 3hdc chain A

Region: 23 - 182
Aligned: 136
Modelled: 155
Confidence: 98.3%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thioredoxin family protein;
PDBTitle: the crystal structure of thioredoxin protein from geobacter2 metallireducens

Phyre2
5 |
| c3lorB_ |

### PDB 3lor chain B

Region: 26 - 179
Aligned: 142
Modelled: 154
Confidence: 98.3%
Identity: 11%
PDB header:isomerase
Chain: B: PDB Molecule:thiol-disulfide isomerase and thioredoxins;
PDBTitle: the crystal structure of a thiol-disulfide isomerase from2 corynebacterium glutamicum to 2.2a

Phyre2
6 |
| d2cvba1 |

### PDB 2cvb chain A domain 1

Region: 23 - 179
Aligned: 143
Modelled: 157
Confidence: 98.2%
Identity: 7%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2
7 |
| d1knga_ |

### PDB 1kng chain A

Region: 27 - 183
Aligned: 140
Modelled: 157
Confidence: 98.2%
Identity: 21%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2
8 |
| c3gl3D_ |

### PDB 3gl3 chain D

Region: 26 - 183
Aligned: 136
Modelled: 155
Confidence: 98.2%
Identity: 15%
PDB header:oxidoreductase
Chain: D: PDB Molecule:putative thiol:disulfide interchange protein
PDBTitle: crystal structure of a putative thiol:disulfide interchange2 protein dsbe from chlorobium tepidum

Phyre2
9 |
| c3kcmC_ |

### PDB 3kcm chain C

Region: 26 - 183
Aligned: 138
Modelled: 152
Confidence: 98.2%
Identity: 13%
PDB header:oxidoreductase
Chain: C: PDB Molecule:thioredoxin family protein;
PDBTitle: the crystal structure of thioredoxin protein from geobacter2 metallireducens

Phyre2
10 |
| c3drnB_ |

### PDB 3drn chain B

Region: 23 - 184
Aligned: 144
Modelled: 154
Confidence: 98.1%
Identity: 13%
PDB header:oxidoreductase
Chain: B: PDB Molecule:peroxiredoxin, bacterioferritin comigratory protein
PDBTitle: the crystal structure of bcp1 from sulfolobus sulfataricus

Phyre2
11 |
| c3hczA_ |

### PDB 3hcz chain A

Region: 23 - 181
Aligned: 142
Modelled: 150
Confidence: 98.1%
Identity: 12%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:possible thiol-disulfide isomerase;
PDBTitle: the crystal structure of a domain of possible thiol-disulfide2 isomerase from cytophaga hutchinsonii atcc 33406.

Phyre2
12 |
| d2b5xa1 |

### PDB 2b5x chain A domain 1

Region: 23 - 177
Aligned: 141
Modelled: 150
Confidence: 98.0%
Identity: 12%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2
13 |
| c3ha9A_ |

### PDB 3ha9 chain A

Region: 18 - 177
Aligned: 144
Modelled: 160
Confidence: 98.0%
Identity: 17%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized thioredoxin-like protein;
PDBTitle: the 1.7a crystal structure of a thioredoxin-like protein from2 aeropyrum pernix

Phyre2
14 |
| c2l5oA_ |

### PDB 2l5o chain A

Region: 26 - 184
Aligned: 140
Modelled: 159
Confidence: 98.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin;
PDBTitle: solution structure of a putative thioredoxin from neisseria2 meningitidis

Phyre2
15 |
| c3lwaA_ |

### PDB 3lwa chain A

Region: 26 - 179
Aligned: 141
Modelled: 154
Confidence: 98.0%
Identity: 15%
PDB header:isomerase
Chain: A: PDB Molecule:secreted thiol-disulfide isomerase;
PDBTitle: the crystal structure of a secreted thiol-disulfide2 isomerase from corynebacterium glutamicum to 1.75a

Phyre2
16 |
| d1e2ya_ |

### PDB 1e2y chain A

Region: 23 - 182
Aligned: 152
Modelled: 155
Confidence: 98.0%
Identity: 12%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2
17 |
| c2b1kA_ |

### PDB 2b1k chain A

Region: 22 - 184
Aligned: 143
Modelled: 163
Confidence: 98.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbe;
PDBTitle: crystal structure of e. coli ccmg protein

Phyre2
18 |
| c3fkfC_ |

### PDB 3fkf chain C

Region: 24 - 176
Aligned: 139
Modelled: 145
Confidence: 98.0%
Identity: 7%
PDB header:oxidoreductase
Chain: C: PDB Molecule:thiol-disulfide oxidoreductase;
PDBTitle: thiol-disulfide oxidoreductase from bacteroides fragilis nctc 9343

Phyre2
19 |
| d2fy6a1 |

### PDB 2fy6 chain A domain 1

Region: 42 - 177
Aligned: 127
Modelled: 136
Confidence: 97.9%
Identity: 10%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2
20 |
| d1jfua_ |

### PDB 1jfu chain A

Region: 17 - 177
Aligned: 144
Modelled: 155
Confidence: 97.9%
Identity: 13%
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Family: Glutathione peroxidase-like

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1st9a_ |
|  | 98.6 | 18 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
2 | c3kh7A_ |
|  | 98.4 | 15 | PDB header:oxidoreductase Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbe; PDBTitle: crystal structure of the periplasmic soluble domain of reduced ccmg2 from pseudomonas aeruginosa
3 | c2hyxA_ |
|  | 98.3 | 16 | PDB header:unknown function Chain: A: PDB Molecule:protein dipz; PDBTitle: structure of the c-terminal domain of dipz from mycobacterium2 tuberculosis
4 | c3hdcA_ |
|  | 98.3 | 14 | PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin family protein; PDBTitle: the crystal structure of thioredoxin protein from geobacter2 metallireducens
5 | c3lorB_ |
|  | 98.3 | 11 | PDB header:isomerase Chain: B: PDB Molecule:thiol-disulfide isomerase and thioredoxins; PDBTitle: the crystal structure of a thiol-disulfide isomerase from2 corynebacterium glutamicum to 2.2a
6 | d2cvba1 |
|  | 98.2 | 7 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
7 | d1knga_ |
|  | 98.2 | 21 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
8 | c3gl3D_ |
|  | 98.2 | 15 | PDB header:oxidoreductase Chain: D: PDB Molecule:putative thiol:disulfide interchange protein PDBTitle: crystal structure of a putative thiol:disulfide interchange2 protein dsbe from chlorobium tepidum
9 | c3kcmC_ |
|  | 98.2 | 13 | PDB header:oxidoreductase Chain: C: PDB Molecule:thioredoxin family protein; PDBTitle: the crystal structure of thioredoxin protein from geobacter2 metallireducens
10 | c3drnB_ |
|  | 98.1 | 13 | PDB header:oxidoreductase Chain: B: PDB Molecule:peroxiredoxin, bacterioferritin comigratory protein PDBTitle: the crystal structure of bcp1 from sulfolobus sulfataricus
11 | c3hczA_ |
|  | 98.1 | 12 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:possible thiol-disulfide isomerase; PDBTitle: the crystal structure of a domain of possible thiol-disulfide2 isomerase from cytophaga hutchinsonii atcc 33406.
12 | d2b5xa1 |
|  | 98.0 | 12 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
13 | c3ha9A_ |
|  | 98.0 | 17 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized thioredoxin-like protein; PDBTitle: the 1.7a crystal structure of a thioredoxin-like protein from2 aeropyrum pernix
14 | c2l5oA_ |
|  | 98.0 | 18 | PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin; PDBTitle: solution structure of a putative thioredoxin from neisseria2 meningitidis
15 | c3lwaA_ |
|  | 98.0 | 15 | PDB header:isomerase Chain: A: PDB Molecule:secreted thiol-disulfide isomerase; PDBTitle: the crystal structure of a secreted thiol-disulfide2 isomerase from corynebacterium glutamicum to 1.75a
16 | d1e2ya_ |
|  | 98.0 | 12 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
17 | c2b1kA_ |
|  | 98.0 | 18 | PDB header:oxidoreductase Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbe; PDBTitle: crystal structure of e. coli ccmg protein
18 | c3fkfC_ |
|  | 98.0 | 7 | PDB header:oxidoreductase Chain: C: PDB Molecule:thiol-disulfide oxidoreductase; PDBTitle: thiol-disulfide oxidoreductase from bacteroides fragilis nctc 9343
19 | d2fy6a1 |
|  | 97.9 | 10 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
20 | d1jfua_ |
|  | 97.9 | 13 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
21 | d2bmxa1 |
| not modelled | 97.9 | 14 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
22 | d1zofa1 |
| not modelled | 97.9 | 13 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
23 | c3or5A_ |
| not modelled | 97.9 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:thiol:disulfide interchange protein, thioredoxin family PDBTitle: crystal structure of thiol:disulfide interchange protein, thioredoxin2 family protein from chlorobium tepidum tls
24 | d1qq2a_ |
| not modelled | 97.9 | 13 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
25 | c3kebB_ |
| not modelled | 97.9 | 14 | PDB header:oxidoreductase Chain: B: PDB Molecule:probable thiol peroxidase; PDBTitle: thiol peroxidase from chromobacterium violaceum
26 | c1zofB_ |
| not modelled | 97.9 | 12 | PDB header:oxidoreductase Chain: B: PDB Molecule:alkyl hydroperoxide-reductase; PDBTitle: crystal structure of alkyl hydroperoxide-reductase (ahpc)2 from helicobacter pylori
27 | c2yzhD_ |
| not modelled | 97.9 | 14 | PDB header:oxidoreductase Chain: D: PDB Molecule:probable thiol peroxidase; PDBTitle: crystal structure of peroxiredoxin-like protein from aquifex aeolicus
28 | c2jszA_ |
| not modelled | 97.8 | 15 | PDB header:oxidoreductase Chain: A: PDB Molecule:probable thiol peroxidase; PDBTitle: solution structure of tpx in the reduced state
29 | d2cx4a1 |
| not modelled | 97.8 | 18 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
30 | c2c0dA_ |
| not modelled | 97.8 | 11 | PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin peroxidase 2; PDBTitle: structure of the mitochondrial 2-cys peroxiredoxin from2 plasmodium falciparum
31 | d1xvwa1 |
| not modelled | 97.8 | 15 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
32 | c3razA_ |
| not modelled | 97.7 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-related protein; PDBTitle: the crystal structure of thioredoxin-related protein from neisseria2 meningitidis serogroup b
33 | c2h66G_ |
| not modelled | 97.7 | 15 | PDB header:structural genomics/oxidoreductase Chain: G: PDB Molecule:pv-pf14_0368; PDBTitle: the crystal structure of plasmodium vivax 2-cys2 peroxiredoxin
34 | c2ywiA_ |
| not modelled | 97.7 | 15 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical conserved protein; PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus
35 | c3erwG_ |
| not modelled | 97.7 | 16 | PDB header:oxidoreductase Chain: G: PDB Molecule:sporulation thiol-disulfide oxidoreductase a; PDBTitle: crystal structure of stoa from bacillus subtilis
36 | c3gknA_ |
| not modelled | 97.7 | 12 | PDB header:oxidoreductase Chain: A: PDB Molecule:bacterioferritin comigratory protein; PDBTitle: insights into the alkyl peroxide reduction activity of xanthomonas2 campestris bacterioferritin comigratory protein from the trapped3 intermediate/ligand complex structures
37 | c3eytA_ |
| not modelled | 97.7 | 16 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein spoa0173; PDBTitle: crystal structure of thioredoxin-like superfamily protein spoa0173
38 | c2bmxB_ |
| not modelled | 97.7 | 14 | PDB header:oxidoreductase Chain: B: PDB Molecule:alkyl hydroperoxidase c; PDBTitle: mycobacterium tuberculosis ahpc
39 | d1qmva_ |
| not modelled | 97.7 | 13 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
40 | d1lu4a_ |
| not modelled | 97.7 | 18 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
41 | c3ia1A_ |
| not modelled | 97.6 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:thio-disulfide isomerase/thioredoxin; PDBTitle: crystal structure of thio-disulfide isomerase from thermus2 thermophilus
42 | c3cmiA_ |
| not modelled | 97.6 | 16 | PDB header:oxidoreductase Chain: A: PDB Molecule:peroxiredoxin hyr1; PDBTitle: crystal structure of glutathione-dependent phospholipid peroxidase2 hyr1 from the yeast saccharomyces cerevisiae
43 | d1zzoa1 |
| not modelled | 97.6 | 21 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
44 | d1psqa_ |
| not modelled | 97.6 | 15 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
45 | c3ixrA_ |
| not modelled | 97.5 | 15 | PDB header:oxidoreductase Chain: A: PDB Molecule:bacterioferritin comigratory protein; PDBTitle: crystal structure of xylella fastidiosa prxq c47s mutant
46 | d1z5ye1 |
| not modelled | 97.5 | 14 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
47 | c2p31B_ |
| not modelled | 97.5 | 13 | PDB header:oxidoreductase Chain: B: PDB Molecule:glutathione peroxidase 7; PDBTitle: crystal structure of human glutathione peroxidase 7
48 | c3me8B_ |
| not modelled | 97.4 | 17 | PDB header:electron transport Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of putative electron transfer protein aq_2194 from2 aquifex aeolicus vf5
49 | c3ewlA_ |
| not modelled | 97.4 | 10 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized conserved protein bf1870; PDBTitle: crystal structure of conserved protein bf1870 of unknown function from2 bacteroides fragilis
50 | c1zyeL_ |
| not modelled | 97.3 | 14 | PDB header:oxidoreductase Chain: L: PDB Molecule:thioredoxin-dependent peroxide reductase; PDBTitle: crystal strucutre analysis of bovine mitochondrial peroxiredoxin iii
51 | c2p5qA_ |
| not modelled | 97.3 | 15 | PDB header:oxidoreductase Chain: A: PDB Molecule:glutathione peroxidase 5; PDBTitle: crystal structure of the poplar glutathione peroxidase 5 in2 the reduced form
52 | c3fw2A_ |
| not modelled | 97.2 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:thiol-disulfide oxidoreductase; PDBTitle: c-terminal domain of putative thiol-disulfide oxidoreductase from2 bacteroides thetaiotaomicron.
53 | c3cynC_ |
| not modelled | 97.2 | 9 | PDB header:oxidoreductase Chain: C: PDB Molecule:probable glutathione peroxidase 8; PDBTitle: the structure of human gpx8
54 | d1uula_ |
| not modelled | 97.2 | 12 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
55 | d2zcta1 |
| not modelled | 97.1 | 17 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
56 | d1we0a1 |
| not modelled | 97.1 | 15 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
57 | c2ywnA_ |
| not modelled | 97.1 | 21 | PDB header:oxidoreductase Chain: A: PDB Molecule:peroxiredoxin-like protein; PDBTitle: crystal structure of peroxiredoxin-like protein from2 sulfolobus tokodaii
58 | d1zyea1 |
| not modelled | 97.0 | 10 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
59 | d1qxha_ |
| not modelled | 97.0 | 15 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
60 | c3eurA_ |
| not modelled | 97.0 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the c-terminal domain of uncharacterized protein2 from bacteroides fragilis nctc 9343
61 | d2b7ka1 |
| not modelled | 96.9 | 11 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
62 | d1xzoa1 |
| not modelled | 96.9 | 12 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
63 | d1n8ja_ |
| not modelled | 96.8 | 15 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
64 | c2v1mA_ |
| not modelled | 96.8 | 14 | PDB header:oxidoreductase Chain: A: PDB Molecule:glutathione peroxidase; PDBTitle: crystal structure of schistosoma mansoni glutathione2 peroxidase
65 | c2xpdC_ |
| not modelled | 96.8 | 15 | PDB header:oxidoreductase Chain: C: PDB Molecule:thiol peroxidase; PDBTitle: reduced thiol peroxidase (tpx) from yersinia pseudotuberculosis
66 | d1gp1a_ |
| not modelled | 96.7 | 9 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
67 | c2he3A_ |
| not modelled | 96.7 | 10 | PDB header:oxidoreductase Chain: A: PDB Molecule:glutathione peroxidase 2; PDBTitle: crystal structure of the selenocysteine to cysteine mutant of human2 glutathionine peroxidase 2 (gpx2)
68 | d1yexa1 |
| not modelled | 96.6 | 14 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
69 | d2h01a1 |
| not modelled | 96.5 | 15 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
70 | d1prxa_ |
| not modelled | 96.4 | 13 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
71 | c3dwvB_ |
| not modelled | 96.4 | 12 | PDB header:oxidoreductase Chain: B: PDB Molecule:glutathione peroxidase-like protein; PDBTitle: glutathione peroxidase-type tryparedoxin peroxidase,2 oxidized form
72 | c2obiA_ |
| not modelled | 96.3 | 11 | PDB header:oxidoreductase Chain: A: PDB Molecule:phospholipid hydroperoxide glutathione PDBTitle: crystal structure of the selenocysteine to cysteine mutant2 of human phospholipid hydroperoxide glutathione peroxidase3 (gpx4)
73 | c2xhfA_ |
| not modelled | 96.3 | 12 | PDB header:oxidoreductase Chain: A: PDB Molecule:peroxiredoxin 5; PDBTitle: crystal structure of peroxiredoxin 5 from alvinella pompejana
74 | d1q98a_ |
| not modelled | 96.1 | 15 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
75 | d2f8aa1 |
| not modelled | 96.1 | 10 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
76 | d1wp0a1 |
| not modelled | 96.0 | 7 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
77 | d1hd2a_ |
| not modelled | 95.9 | 16 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
78 | d2a4va1 |
| not modelled | 95.7 | 10 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
79 | d1xcca_ |
| not modelled | 95.4 | 12 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
80 | c2r37A_ |
| not modelled | 95.0 | 13 | PDB header:oxidoreductase Chain: A: PDB Molecule:glutathione peroxidase 3; PDBTitle: crystal structure of human glutathione peroxidase 3 (selenocysteine to2 glycine mutant)
81 | c2v2gC_ |
| not modelled | 94.9 | 12 | PDB header:oxidoreductase Chain: C: PDB Molecule:peroxiredoxin 6; PDBTitle: crystal structure of the c45s mutant of the peroxiredoxin 62 of arenicola marina. monoclinic form
82 | c2rliA_ |
| not modelled | 94.8 | 13 | PDB header:metal transport Chain: A: PDB Molecule:sco2 protein homolog, mitochondrial; PDBTitle: solution structure of cu(i) human sco2
83 | d2cv4a1 |
| not modelled | 94.8 | 12 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
84 | d1o8xa_ |
| not modelled | 94.5 | 11 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
85 | d1xvqa_ |
| not modelled | 94.4 | 16 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
86 | d1z6na1 |
| not modelled | 94.1 | 14 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase
87 | c2wfcD_ |
| not modelled | 93.4 | 17 | PDB header:oxidoreductase Chain: D: PDB Molecule:peroxiredoxin 5; PDBTitle: crystal structure of peroxiredoxin 5 from arenicola marina
88 | c2b7kD_ |
| not modelled | 92.8 | 10 | PDB header:metal binding protein Chain: D: PDB Molecule:sco1 protein; PDBTitle: crystal structure of yeast sco1
89 | d1o73a_ |
| not modelled | 91.7 | 8 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
90 | c2k6vA_ |
| not modelled | 91.4 | 15 | PDB header:electron transport Chain: A: PDB Molecule:putative cytochrome c oxidase assembly protein; PDBTitle: solution structures of apo sco1 protein from thermus2 thermophilus
91 | c2l57A_ |
| not modelled | 90.7 | 12 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of an uncharacterized thioredoin-like protein from2 clostridium perfringens
92 | c3umaC_ |
| not modelled | 88.7 | 19 | PDB header:oxidoreductase Chain: C: PDB Molecule:hypothetical peroxiredoxin protein; PDBTitle: crystal structure of a hypothetical peroxiredoxin protein frm2 sinorhizobium meliloti
93 | c2pwjB_ |
| not modelled | 86.2 | 15 | PDB header:oxidoreductase Chain: B: PDB Molecule:mitochondrial peroxiredoxin; PDBTitle: structure of a mitochondrial type ii peroxiredoxin from2 pisum sativum
94 | d1tp9a1 |
| not modelled | 86.1 | 17 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
95 | c2kucA_ |
| not modelled | 76.7 | 18 | PDB header:isomerase Chain: A: PDB Molecule:putative disulphide-isomerase; PDBTitle: solution structure of a putative disulphide-isomerase from bacteroides2 thetaiotaomicron
96 | d1i5ga_ |
| not modelled | 76.0 | 11 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
97 | d1y6ja2 |
| not modelled | 72.9 | 17 | Fold:LDH C-terminal domain-like Superfamily:LDH C-terminal domain-like Family:Lactate & malate dehydrogenases, C-terminal domain
98 | c2v6bB_ |
| not modelled | 72.8 | 19 | PDB header:oxidoreductase Chain: B: PDB Molecule:l-lactate dehydrogenase; PDBTitle: crystal structure of lactate dehydrogenase from deinococcus2 radiodurans (apo form)
99 | d1xiya1 |
| not modelled | 68.7 | 15 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like
100 | d1t2da2 |
| not modelled | 67.3 | 13 | Fold:LDH C-terminal domain-like Superfamily:LDH C-terminal domain-like Family:Lactate & malate dehydrogenases, C-terminal domain
101 | d1oc4a2 |
| not modelled | 64.0 | 9 | Fold:LDH C-terminal domain-like Superfamily:LDH C-terminal domain-like Family:Lactate & malate dehydrogenases, C-terminal domain
102 | c3gnjD_ |
| not modelled | 57.6 | 14 | PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb
103 | c2ju5A_ |
| not modelled | 57.3 | 18 | PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin disulfide isomerase; PDBTitle: dsbh oxidoreductase
104 | c3hz4A_ |
| not modelled | 53.9 | 9 | PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from methanosarcina mazei
105 | c3f9uA_ |
| not modelled | 50.2 | 21 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative exported cytochrome c biogenesis-related protein; PDBTitle: crystal structure of c-terminal domain of putative exported cytochrome2 c biogenesis-related protein from bacteroides fragilis
106 | d1zmaa1 |
| not modelled | 48.7 | 21 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase
107 | d1pzga2 |
| not modelled | 46.6 | 13 | Fold:LDH C-terminal domain-like Superfamily:LDH C-terminal domain-like Family:Lactate & malate dehydrogenases, C-terminal domain
108 | c2wshC_ |
| not modelled | 46.1 | 9 | PDB header:hydrolase Chain: C: PDB Molecule:endonuclease ii; PDBTitle: structure of bacteriophage t4 endoii e118a mutant
109 | c3gr0D_ |
| not modelled | 46.0 | 21 | PDB header:membrane protein Chain: D: PDB Molecule:protein prgh; PDBTitle: periplasmic domain of the t3ss inner membrane protein prgh from2 s.typhimurium (fragment 170-362)
110 | c3fk8A_ |
| not modelled | 44.7 | 27 | PDB header:isomerase Chain: A: PDB Molecule:disulphide isomerase; PDBTitle: the crystal structure of disulphide isomerase from xylella fastidiosa2 temecula1
111 | d2d30a1 |
| not modelled | 41.9 | 27 | Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Cytidine deaminase
112 | c2l6dA_ |
| not modelled | 40.7 | 21 | PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution structure of desulfothioredoxin from desulfovibrio vulgaris2 hildenborough in its reduced form
113 | d2fwha1 |
| not modelled | 40.6 | 17 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase
114 | d1nw2a_ |
| not modelled | 39.9 | 16 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase
115 | c2e0qA_ |
| not modelled | 39.2 | 30 | PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of k53e thioredoxin from sulfolobus2 tokodaii strain7
116 | c2pptA_ |
| not modelled | 37.0 | 12 | PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-2; PDBTitle: crystal structure of thioredoxin-2
117 | d2ooka1 |
| not modelled | 35.7 | 19 | Fold:SpoIIaa-like Superfamily:SpoIIaa-like Family:Sfri0576-like
118 | d5mdha2 |
| not modelled | 35.0 | 9 | Fold:LDH C-terminal domain-like Superfamily:LDH C-terminal domain-like Family:Lactate & malate dehydrogenases, C-terminal domain
119 | c3ul3A_ |
| not modelled | 34.1 | 14 | PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: structural insights into thioredoxin-2: a component of malaria2 parasite protein secretion machinery
120 | d1nm3a2 |
| not modelled | 33.9 | 18 | Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0