BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (266 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P27848 Uncharacterized protein yigL n=168 Tax=Bacteria ...   555   e-157
UniRef50_Q7MQB3 Predicted hydrolase n=59 Tax=Gammaproteobacteria...   271   2e-71
UniRef50_Q8KA73 Uncharacterized protein BUsg_029 n=5 Tax=Buchner...   248   2e-64
UniRef50_A6FJC9 Putative uncharacterized protein n=1 Tax=Moritel...   239   1e-61
UniRef50_A0KR21 Hydrolase, Cof family n=3 Tax=Aeromonadaceae Rep...   230   3e-59
UniRef50_P44771 Uncharacterized protein HI0597 n=32 Tax=Pasteure...   226   6e-58
UniRef50_C6JR95 Hydrolase n=2 Tax=Fusobacterium RepID=C6JR95_FUSVA    211   1e-53
UniRef50_C3WDD5 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC ...   211   2e-53
UniRef50_A5FGB8 Cof-like hydrolase n=1 Tax=Flavobacterium johnso...   200   3e-50
UniRef50_Q4D2M6 Haloacid dehalogenase-like hydrolase, putative n...   198   2e-49
UniRef50_A8GAR8 HMP-PP phosphatase n=39 Tax=Enterobacteriaceae R...   192   1e-47
UniRef50_D0A841 Haloacid dehalogenase-like hydrolase, putative n...   186   5e-46
UniRef50_A1V919 HAD hydrolase, IIB family n=56 Tax=Betaproteobac...   186   7e-46
UniRef50_C3WN06 Hydrolase n=12 Tax=Fusobacterium RepID=C3WN06_9FUSO   183   4e-45
UniRef50_A7ZIK4 HMP-PP phosphatase n=87 Tax=Bacteria RepID=COF_E...   178   2e-43
UniRef50_A1SZR3 Cof-like hydrolase n=2 Tax=Psychromonas RepID=A1...   177   4e-43
UniRef50_A6T5I9 HMP-PP phosphatase n=18 Tax=Bacteria RepID=COF_K...   175   1e-42
UniRef50_Q7N6X1 Similar to unknown protein n=2 Tax=Photorhabdus ...   174   2e-42
UniRef50_Q4DMD3 Haloacid dehalogenase hydrolase, putative n=2 Ta...   170   6e-41
UniRef50_A4HGI1 Putative uncharacterized protein n=4 Tax=Leishma...   167   3e-40
UniRef50_Q4Q8C9 Haloacid dehalogenase-like hydrolase, putative n...   165   2e-39
UniRef50_D1AMP5 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepI...   164   4e-39
UniRef50_C6K3T4 Haloacid dehalogenase-like hydrolase-like protei...   159   1e-37
UniRef50_C3WDI3 Hydrolase n=2 Tax=Fusobacterium mortiferum ATCC ...   155   9e-37
UniRef50_Q4Q8D1 Haloacid dehalogenase-like hydrolase-like protei...   154   4e-36
UniRef50_C7ND82 Cof-like hydrolase n=4 Tax=Leptotrichia RepID=C7...   150   6e-35
UniRef50_D1AWH0 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepI...   148   2e-34
UniRef50_C7ND81 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7...   147   3e-34
UniRef50_Q1QY75 Cof protein n=1 Tax=Chromohalobacter salexigens ...   147   3e-34
UniRef50_Q7NXV0 Putative uncharacterized protein n=1 Tax=Chromob...   142   9e-33
UniRef50_C6K3T2 Haloacid dehalogenase-like hydrolase-like protei...   139   1e-31
UniRef50_Q384S8 Haloacid dehalogenase hydrolase, putative n=3 Ta...   137   3e-31
UniRef50_B9Z762 Cof-like hydrolase n=1 Tax=Lutiella nitroferrum ...   134   2e-30
UniRef50_A4HGI8 Haloacid dehalogenase-like hydrolase-like protei...   134   4e-30
UniRef50_B5RQP7 Uncharacterized conserved protein n=22 Tax=Borre...   127   3e-28
UniRef50_Q4Q8C8 Haloacid dehalogenase-like hydrolase-like protei...   124   3e-27
UniRef50_C6K3T3 Haloacid dehalogenase-like hydrolase-like protei...   122   1e-26
UniRef50_C3WAR4 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC ...   116   9e-25
UniRef50_D0Z8V8 Hydrolase, Cof family n=1 Tax=Edwardsiella tarda...   112   9e-24
UniRef50_Q3D5Y9 Hydrolase, haloacid dehalogenase-like family n=9...   112   1e-23
UniRef50_D1AJW8 Cof-like hydrolase n=1 Tax=Sebaldella termitidis...   111   3e-23
UniRef50_C6JK34 Hydrolase n=2 Tax=Fusobacterium RepID=C6JK34_FUSVA    110   6e-23
UniRef50_Q897B3 Putative haloacid dehalogenase-like hydrolase n=...   109   9e-23
UniRef50_C6CW76 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CW...   108   2e-22
UniRef50_A1QZK7 Hydrolase (HAD superfamily) n=8 Tax=Borrelia Rep...   107   4e-22
UniRef50_C2KV90 HAD superfamily hydrolase n=1 Tax=Oribacterium s...   106   9e-22
UniRef50_C6PXU7 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...   103   6e-21
UniRef50_C6QV31 Cof-like hydrolase n=1 Tax=Geobacillus sp. Y4.1M...   102   2e-20
UniRef50_C0R158 Putative hydrolase n=1 Tax=Brachyspira hyodysent...   102   2e-20
UniRef50_B9DT57 Putative haloacid dehalogenase-like hydrolase n=...   101   2e-20
UniRef50_UPI0001BC5F8F HAD superfamily hydrolase n=3 Tax=Fusobac...   101   3e-20
UniRef50_A1HSX6 Cof-like hydrolase n=1 Tax=Thermosinus carboxydi...   101   3e-20
UniRef50_D1AIM0 Cof-like hydrolase n=1 Tax=Sebaldella termitidis...   101   3e-20
UniRef50_C1QE38 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...   100   5e-20
UniRef50_C6P8T7 Cof-like hydrolase n=1 Tax=Thermoanaerobacterium...   100   6e-20
UniRef50_B5YEJ7 Phosphatase YidA, putative n=2 Tax=Dictyoglomus ...    99   2e-19
UniRef50_C6JKA3 HAD-superfamily hydrolase subfamily IIB n=3 Tax=...    99   2e-19
UniRef50_A4XJ23 Cof-like hydrolase n=2 Tax=Clostridia RepID=A4XJ...    98   2e-19
UniRef50_Q4KBY5 Cof-like hydrolase family protein n=8 Tax=Pseudo...    98   2e-19
UniRef50_C3K9U8 Putative haloacid dehalogenase-like hydrolase n=...    98   2e-19
UniRef50_B8DIC3 Hydrolase, Cof family n=18 Tax=Listeria RepID=B8...    98   3e-19
UniRef50_UPI000196CFC2 hypothetical protein CATMIT_02842 n=1 Tax...    98   4e-19
UniRef50_Q0TQ35 HAD hydrolase, IIB family n=9 Tax=Clostridium pe...    97   4e-19
UniRef50_Q8RF49 Hydrolase (HAD superfamily) n=10 Tax=Fusobacteri...    97   6e-19
UniRef50_P94592 Uncharacterized phosphatase ywpJ n=7 Tax=Bacilla...    96   9e-19
UniRef50_C5D7Z3 Cof-like hydrolase n=1 Tax=Geobacillus sp. WCH70...    96   9e-19
UniRef50_B8CYJ2 Cof-like hydrolase n=1 Tax=Halothermothrix oreni...    96   1e-18
UniRef50_C7RFK7 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7...    96   1e-18
UniRef50_A6LB32 Haloacid dehalogenase-like hydrolase n=23 Tax=Ba...    96   2e-18
UniRef50_A9KKJ5 Cof-like hydrolase n=3 Tax=Clostridiales RepID=A...    95   3e-18
UniRef50_A3MZH9 Predicted hydrolases of the HAD superfamily n=9 ...    94   4e-18
UniRef50_B0ADP8 Putative uncharacterized protein n=1 Tax=Clostri...    94   5e-18
UniRef50_Q0B097 Putative uncharacterized protein n=1 Tax=Syntrop...    93   7e-18
UniRef50_C9KQH1 HAD phosphatase family protein n=2 Tax=Clostridi...    93   7e-18
UniRef50_A6TLP5 Cof-like hydrolase n=2 Tax=Firmicutes RepID=A6TL...    93   8e-18
UniRef50_B0K375 Cof-like hydrolase n=11 Tax=Thermoanaerobacteral...    93   9e-18
UniRef50_Q2RLU7 HAD-superfamily hydrolase subfamily IIB n=1 Tax=...    93   1e-17
UniRef50_B0K874 Cof-like hydrolase n=10 Tax=Thermoanaerobacterac...    92   1e-17
UniRef50_C6PMT7 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...    92   1e-17
UniRef50_C6JLL1 Hydrolase n=2 Tax=Fusobacterium RepID=C6JLL1_FUSVA     92   1e-17
UniRef50_C9XMM6 Putative hydrolase n=4 Tax=Clostridium difficile...    92   1e-17
UniRef50_Q97ES2 HAD superfamily hydrolase n=1 Tax=Clostridium ac...    92   2e-17
UniRef50_C4L3P2 Cof-like hydrolase n=2 Tax=Exiguobacterium RepID...    92   2e-17
UniRef50_Q8ENE7 Hypothetical conserved protein n=1 Tax=Oceanobac...    92   2e-17
UniRef50_C7NEL2 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7...    92   2e-17
UniRef50_B1L8F5 Cof-like hydrolase n=6 Tax=Thermotogaceae RepID=...    92   2e-17
UniRef50_C0Z8L2 Putative uncharacterized protein n=1 Tax=Breviba...    91   3e-17
UniRef50_C3WG77 HAD hydrolase n=1 Tax=Fusobacterium mortiferum A...    91   3e-17
UniRef50_A0AEX0 Complete genome n=17 Tax=Listeria RepID=A0AEX0_L...    91   4e-17
UniRef50_C8WUD0 Cof-like hydrolase n=2 Tax=Alicyclobacillus acid...    91   4e-17
UniRef50_C5NXD6 Phosphatase YidA n=1 Tax=Gemella haemolysans ATC...    91   4e-17
UniRef50_C2EBE1 HAD superfamily hydrolase n=1 Tax=Lactobacillus ...    91   4e-17
UniRef50_C5NX92 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...    91   4e-17
UniRef50_B7HYF7 Hydrolase, haloacid dehalogenase-like family n=8...    91   5e-17
UniRef50_Q03M97 Predicted hydrolase of the HAD superfamily n=68 ...    91   5e-17
UniRef50_B5RRM7 Hydrolase n=20 Tax=Borrelia RepID=B5RRM7_BORRA         91   5e-17
UniRef50_UPI0001788F0C Cof-like hydrolase n=1 Tax=Geobacillus sp...    91   5e-17
UniRef50_A5Z551 Putative uncharacterized protein n=1 Tax=Eubacte...    91   6e-17
UniRef50_Q67R81 Haloacid dehalogenase-like hydrolase n=1 Tax=Sym...    90   6e-17
UniRef50_Q2JQT8 HAD hydrolase, IIB family n=1 Tax=Synechococcus ...    90   6e-17
UniRef50_A6TMX9 Cof-like hydrolase n=1 Tax=Alkaliphilus metallir...    90   7e-17
UniRef50_B1BZI7 Putative uncharacterized protein n=2 Tax=Clostri...    90   8e-17
UniRef50_B2V561 HAD-superfamily hydrolase, subfamily IIB n=14 Ta...    90   9e-17
UniRef50_B8DEX6 Phosphatase YidA n=17 Tax=Listeria RepID=B8DEX6_...    90   1e-16
UniRef50_Q1WS49 Hydrolase, HAD superfamily n=2 Tax=Lactobacillus...    89   1e-16
UniRef50_A7AZV2 Putative uncharacterized protein n=1 Tax=Ruminoc...    89   1e-16
UniRef50_A8SLC7 Putative uncharacterized protein n=1 Tax=Parvimo...    89   1e-16
UniRef50_UPI0001788505 Cof-like hydrolase n=1 Tax=Geobacillus sp...    89   1e-16
UniRef50_C4RHE6 HAD-superfamily hydrolase, subfamily IIB n=2 Tax...    89   1e-16
UniRef50_C5EF13 Putative uncharacterized protein n=2 Tax=Clostri...    89   1e-16
UniRef50_Q819K1 Hydrolase (HAD superfamily) n=77 Tax=Bacillaceae...    89   2e-16
UniRef50_B9DTI8 Haloacid dehalogenase-like hydrolase n=1 Tax=Str...    89   2e-16
UniRef50_C1C848 Hydrolase n=29 Tax=Streptococcus RepID=C1C848_STRP7    89   2e-16
UniRef50_A8U9P8 Hydrolase, haloacid dehalogenase-like family pro...    89   2e-16
UniRef50_A8UDR5 Putative hydrolase, haloacid dehalogenase family...    88   3e-16
UniRef50_B2THH0 HAD superfamily hydrolase n=3 Tax=Clostridium bo...    88   3e-16
UniRef50_B7C7C0 Putative uncharacterized protein n=1 Tax=Eubacte...    88   4e-16
UniRef50_Q5WG82 HAD superfamily hydrolase n=1 Tax=Bacillus claus...    87   4e-16
UniRef50_B0N4M8 Putative uncharacterized protein n=3 Tax=Bacteri...    87   6e-16
UniRef50_A7VTJ0 Putative uncharacterized protein n=1 Tax=Clostri...    87   6e-16
UniRef50_C2EN69 HAD family hydrolase n=7 Tax=Firmicutes RepID=C2...    87   6e-16
UniRef50_P42962 Uncharacterized protein ycsE n=9 Tax=Bacillus Re...    87   6e-16
UniRef50_C2BEV0 HAD superfamily hydrolase n=1 Tax=Anaerococcus l...    87   6e-16
UniRef50_Q56637 ORF2 n=2 Tax=Vibrio cholerae RepID=Q56637_VIBCH        87   7e-16
UniRef50_A7Z8Z6 Putative uncharacterized protein n=2 Tax=Bacillu...    87   7e-16
UniRef50_A0R632 Cof-like hydrolase n=33 Tax=Corynebacterineae Re...    87   8e-16
UniRef50_C1I280 HAD hydrolase n=1 Tax=Clostridium sp. 7_2_43FAA ...    86   1e-15
UniRef50_B9CMS8 HAD-superfamily hydrolase, subfamily IIB family ...    86   1e-15
UniRef50_C0EYZ2 Putative uncharacterized protein n=1 Tax=Eubacte...    86   1e-15
UniRef50_C6PUS4 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...    86   1e-15
UniRef50_C2HD37 HAD superfamily hydrolase n=12 Tax=Enterococcus ...    86   1e-15
UniRef50_A6LQL6 Cof-like hydrolase n=1 Tax=Clostridium beijerinc...    86   1e-15
UniRef50_C8P0W5 Phosphatase YidA n=1 Tax=Erysipelothrix rhusiopa...    86   2e-15
UniRef50_C7HV82 HAD phosphatase superfamily protein n=1 Tax=Anae...    85   2e-15
UniRef50_Q03FP9 Predicted hydrolase of the HAD superfamily n=28 ...    85   2e-15
UniRef50_B8I4P5 Cof-like hydrolase n=2 Tax=Clostridium RepID=B8I...    85   2e-15
UniRef50_A3DFI2 Cof-like hydrolase n=5 Tax=Clostridiales RepID=A...    85   2e-15
UniRef50_B7GIG0 Predicted hydrolase of the HAD superfamily n=3 T...    85   3e-15
UniRef50_C4G5S2 Putative uncharacterized protein n=1 Tax=Abiotro...    85   3e-15
UniRef50_C0X6C9 HAD superfamily hydrolase n=22 Tax=Enterococcus ...    84   4e-15
UniRef50_A3I4Q5 Cof-like hydrolase n=3 Tax=Bacillaceae RepID=A3I...    84   4e-15
UniRef50_Q03GV9 Predicted hydrolase of the HAD superfamily n=2 T...    84   5e-15
UniRef50_Q8ELU0 Hypothetical conserved protein n=1 Tax=Oceanobac...    84   5e-15
UniRef50_A8VVZ4 Ribonuclease H n=1 Tax=Bacillus selenitireducens...    84   6e-15
UniRef50_A6LX51 Cof-like hydrolase n=3 Tax=Clostridium RepID=A6L...    84   6e-15
UniRef50_C5RPZ1 Cof-like hydrolase n=1 Tax=Clostridium cellulovo...    84   6e-15
UniRef50_C6AQ91 Cof protein n=4 Tax=Bacteria RepID=C6AQ91_AGGAN        84   7e-15
UniRef50_C4FY88 Putative uncharacterized protein n=1 Tax=Catonel...    83   7e-15
UniRef50_Q3AFE4 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...    83   8e-15
UniRef50_C9LXL5 HAD-superfamily hydrolase, family protein IIB n=...    83   8e-15
UniRef50_C6CY06 Cof-like hydrolase n=3 Tax=Paenibacillaceae RepI...    83   9e-15
UniRef50_C8W906 Cof-like hydrolase n=5 Tax=Coriobacteriaceae Rep...    83   1e-14
UniRef50_A9B0P7 Cof-like hydrolase n=1 Tax=Herpetosiphon auranti...    83   1e-14
UniRef50_Q71XA3 HAD-superfamily hydrolase, subfamily IIB n=19 Ta...    83   1e-14
UniRef50_A5UZ29 Cof-like hydrolase n=2 Tax=Roseiflexus RepID=A5U...    83   1e-14
UniRef50_C9LXL4 HAD hydrolase, IIB family n=1 Tax=Selenomonas sp...    83   1e-14
UniRef50_C4IB07 Cof protein n=1 Tax=Clostridium butyricum E4 str...    82   1e-14
UniRef50_A4EA96 Putative uncharacterized protein n=1 Tax=Collins...    82   1e-14
UniRef50_C1D022 Putative uncharacterized protein n=2 Tax=Deinoco...    82   1e-14
UniRef50_C2DYX9 HAD superfamily hydrolase n=8 Tax=Lactobacillus ...    82   2e-14
UniRef50_C4FT61 Putative uncharacterized protein n=1 Tax=Catonel...    82   2e-14
UniRef50_C2KAT0 Possible sugar-phosphatase n=1 Tax=Chryseobacter...    82   2e-14
UniRef50_C2LPY8 HAD-superfamily hydrolase, subfamily IIB n=5 Tax...    82   2e-14
UniRef50_C1P783 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36...    82   2e-14
UniRef50_B0NZ00 Putative uncharacterized protein n=1 Tax=Clostri...    82   2e-14
UniRef50_C4L8T6 Cof-like hydrolase n=1 Tax=Tolumonas auensis DSM...    82   2e-14
UniRef50_C8RSV0 HAD family hydrolase n=2 Tax=Corynebacterium jei...    82   2e-14
UniRef50_P0A8Y6 Phosphatase yidA n=235 Tax=cellular organisms Re...    82   3e-14
UniRef50_UPI000196B980 hypothetical protein CATMIT_00184 n=1 Tax...    82   3e-14
UniRef50_B0P090 Putative uncharacterized protein n=2 Tax=Clostri...    81   3e-14
UniRef50_Q03YR8 Predicted hydrolase of the HAD superfamily n=3 T...    81   3e-14
UniRef50_C0C6F9 Putative uncharacterized protein n=1 Tax=Clostri...    81   4e-14
UniRef50_A6LS28 Cof-like hydrolase n=4 Tax=Bacteria RepID=A6LS28...    81   5e-14
UniRef50_B1MW64 Predicted hydrolase of the HAD superfamily n=4 T...    81   5e-14
UniRef50_A7VIL5 Putative uncharacterized protein n=1 Tax=Clostri...    80   5e-14
UniRef50_D2RIN9 Cof-like hydrolase n=2 Tax=Acidaminococcus RepID...    80   5e-14
UniRef50_C9BZM0 HAD-superfamily hydrolase n=12 Tax=Enterococcus ...    80   5e-14
UniRef50_Q5FQA0 Putative hydrolase of the HAD superfamily n=1 Ta...    80   6e-14
UniRef50_C4XFJ4 Putative uncharacterized protein n=1 Tax=Mycopla...    80   6e-14
UniRef50_B4CZE7 Cof-like hydrolase n=1 Tax=Chthoniobacter flavus...    80   6e-14
UniRef50_C5RM50 Cof-like hydrolase n=1 Tax=Clostridium cellulovo...    80   6e-14
UniRef50_B0P1S7 Putative uncharacterized protein n=2 Tax=Clostri...    80   7e-14
UniRef50_Q38VQ4 Putative hydrolase, haloacid dehalogenase family...    80   8e-14
UniRef50_C6PVB1 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...    80   9e-14
UniRef50_A7HK89 Cof-like hydrolase n=1 Tax=Fervidobacterium nodo...    80   9e-14
UniRef50_A4F639 Cof protein n=1 Tax=Saccharopolyspora erythraea ...    80   9e-14
UniRef50_A8HYJ4 Haloacid dehalogenase-like hydrolase n=1 Tax=Chl...    80   1e-13
UniRef50_D1D7N6 Predicted protein n=10 Tax=Proteobacteria RepID=...    79   1e-13
UniRef50_B9CKY2 Phosphatase YidA n=1 Tax=Atopobium rimae ATCC 49...    79   1e-13
UniRef50_UPI00018506A2 hypothetical protein Bcoam_01805 n=1 Tax=...    79   1e-13
UniRef50_B5CTA9 Putative uncharacterized protein n=4 Tax=Clostri...    79   1e-13
UniRef50_A8VQS9 Type III restriction enzyme, res subunit n=1 Tax...    79   1e-13
UniRef50_C6CYC3 Cof-like hydrolase n=1 Tax=Paenibacillus sp. JDR...    79   2e-13
UniRef50_A5KNX9 Putative uncharacterized protein n=8 Tax=Clostri...    79   2e-13
UniRef50_B3PMC9 COF family HAD hydrolase protein n=2 Tax=Mycopla...    79   2e-13
UniRef50_UPI0001AF1344 hypothetical protein SghaA1_18547 n=5 Tax...    79   2e-13
UniRef50_C2H8K0 HAD superfamily hydrolase n=17 Tax=Enterococcus ...    78   2e-13
UniRef50_C4DU72 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...    78   3e-13
UniRef50_B2V2P9 HAD hydrolase, IIB family n=7 Tax=Clostridium Re...    78   3e-13
UniRef50_Q183K1 Putative hydrolase n=5 Tax=Clostridium difficile...    78   3e-13
UniRef50_Q97F14 HAD superfamily hydrolase n=1 Tax=Clostridium ac...    78   3e-13
UniRef50_A8MEY7 Cof-like hydrolase n=2 Tax=Alkaliphilus RepID=A8...    78   3e-13
UniRef50_A6W4K6 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...    78   3e-13
UniRef50_C3WB32 Hydrolase n=3 Tax=Fusobacterium RepID=C3WB32_FUSMR     78   3e-13
UniRef50_C7HWS9 Cof family protein n=2 Tax=Anaerococcus RepID=C7...    78   4e-13
UniRef50_A6LZV6 Cof-like hydrolase n=1 Tax=Clostridium beijerinc...    78   4e-13
UniRef50_C5WEL1 Putative uncharacterized protein n=1 Tax=Strepto...    77   4e-13
UniRef50_C4Z320 Putative uncharacterized protein n=2 Tax=Bacteri...    77   4e-13
UniRef50_C4V675 HAD superfamily hydrolase n=1 Tax=Selenomonas fl...    77   5e-13
UniRef50_B2GGK0 Putative uncharacterized protein n=1 Tax=Kocuria...    77   5e-13
UniRef50_C5RCK1 HAD superfamily hydrolase n=1 Tax=Weissella para...    77   5e-13
UniRef50_P44447 Uncharacterized protein HI0003 n=16 Tax=Haemophi...    77   6e-13
UniRef50_Q7MBY0 Predicted hydrolase n=44 Tax=Gammaproteobacteria...    77   6e-13
UniRef50_Q5HPL1 Hydrolase, haloacid dehalogenase-like family n=6...    77   7e-13
UniRef50_Q5HRI8 Hydrolase, haloacid dehalogenase-like family n=6...    77   8e-13
UniRef50_Q04GT8 Predicted hydrolase of the HAD superfamily n=2 T...    77   9e-13
UniRef50_C9LLD7 HAD hydrolase, IIB family n=1 Tax=Dialister invi...    77   9e-13
UniRef50_C7HRV4 Hydrolase (HAD superfamily) n=1 Tax=Anaerococcus...    77   9e-13
UniRef50_C2D871 Sugar-phosphatase n=1 Tax=Atopobium vaginae DSM ...    76   1e-12
UniRef50_A7GS76 Cof-like hydrolase n=73 Tax=Bacillus RepID=A7GS7...    76   1e-12
UniRef50_C8P8B9 Sugar phosphatase SupH n=1 Tax=Lactobacillus ant...    76   1e-12
UniRef50_B0MA15 Putative uncharacterized protein n=2 Tax=Clostri...    76   1e-12
UniRef50_UPI000196AEDD hypothetical protein CATMIT_00603 n=1 Tax...    76   1e-12
UniRef50_A8UBX5 Putative uncharacterized protein n=1 Tax=Carnoba...    76   1e-12
UniRef50_C7N949 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7...    76   1e-12
UniRef50_Q6NEN3 Putative uncharacterized protein n=1 Tax=Coryneb...    76   1e-12
UniRef50_UPI0001BC55F4 hypothetical protein FulcA4_13722 n=1 Tax...    76   1e-12
UniRef50_A8RS01 Putative uncharacterized protein n=2 Tax=Clostri...    76   1e-12
UniRef50_A0Q2R8 Cof-like hydrolase n=1 Tax=Clostridium novyi NT ...    75   2e-12
UniRef50_A9H332 Cof-like hydrolase n=3 Tax=Acetobacteraceae RepI...    75   2e-12
UniRef50_Q03GE4 Predicted hydrolase of the HAD superfamily n=2 T...    75   2e-12
UniRef50_D1YD13 Cof-like hydrolase n=3 Tax=Propionibacterium acn...    75   2e-12
UniRef50_A7VNH3 Putative uncharacterized protein n=1 Tax=Clostri...    75   2e-12
UniRef50_Q03T33 Predicted hydrolase of the HAD superfamily n=9 T...    75   2e-12
UniRef50_UPI0001973D90 HAD family hydrolase n=1 Tax=Clostridium ...    75   2e-12
UniRef50_Q5XD45 Putative hydrolase M6_Spy0533 n=25 Tax=Streptoco...    75   2e-12
UniRef50_C4FTB9 Putative uncharacterized protein n=1 Tax=Catonel...    75   2e-12
UniRef50_D1PLJ0 Hydrolase n=1 Tax=Subdoligranulum variabile DSM ...    75   3e-12
UniRef50_Q02XE2 Predicted hydrolase of the HAD superfamily n=4 T...    75   3e-12
UniRef50_Q5WF79 HAD superfamily hydrolase n=4 Tax=Bacillaceae Re...    75   3e-12
UniRef50_C9XLD9 Putative hydrolase n=7 Tax=Clostridium difficile...    75   3e-12
UniRef50_C2V4H7 Cof-like hydrolase n=5 Tax=Bacillus cereus RepID...    75   3e-12
UniRef50_UPI000197CA00 hypothetical protein PretD1_00540 n=1 Tax...    75   3e-12
UniRef50_Q6KIP5 COF family HAD hydrolase protein n=1 Tax=Mycopla...    75   3e-12
UniRef50_Q0TU23 HAD-superfamily hydrolase, subfamily IIB n=7 Tax...    75   3e-12
UniRef50_A6LB33 Haloacid dehalogenase-like hydrolase n=34 Tax=Ba...    74   4e-12
UniRef50_D0BJQ5 Cof family protein n=2 Tax=Granulicatella RepID=...    74   4e-12
UniRef50_C8PSD2 Hydrolase n=1 Tax=Treponema vincentii ATCC 35580...    74   4e-12
UniRef50_Q0SUS9 Cof-like hydrolase, HAD-superfamily, subfamily I...    74   4e-12
UniRef50_Q04BG8 Predicted hydrolase of the HAD superfamily n=13 ...    74   4e-12

>UniRef50_P27848 Uncharacterized protein yigL n=168 Tax=Bacteria RepID=YIGL_ECOLI
          Length = 266

 Score =  555 bits (1429), Expect = e-157,   Method: Compositional matrix adjust.
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS
Sbjct: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE
Sbjct: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT
Sbjct: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD
Sbjct: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240

Query: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266
           LHPELEVIGTNADDAVPHYLRKLYLS
Sbjct: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266


>UniRef50_Q7MQB3 Predicted hydrolase n=59 Tax=Gammaproteobacteria RepID=Q7MQB3_VIBVY
          Length = 276

 Score =  271 bits (692), Expect = 2e-71,   Method: Compositional matrix adjust.
 Identities = 129/265 (48%), Positives = 188/265 (70%), Gaps = 2/265 (0%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VASDLDGTLL+P+H LS ++K+TLK L  +G  F+FATGRHHVDV  IR  + I +YM
Sbjct: 12  KIVASDLDGTLLAPNHQLSEFSKQTLKALHEQGYTFIFATGRHHVDVAGIRAQVGIPAYM 71

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ITSNGARVHD    L+++ N+  ++   +  +V  +P+I  ++Y++++W +NR      +
Sbjct: 72  ITSNGARVHDQHDQLMYSKNVPAELVQPVIDIVKQDPEIFVHLYQNEDWRLNREDEVMRK 131

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTC--DSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           F +E  F Y +Y+      +G++K+FFT     HE L+  E  +   +GD++N++FST  
Sbjct: 132 FHEETGFTYKVYDIDNAPTDGIAKIFFTHPEQDHEHLVGFENQLREAFGDQLNIAFSTPW 191

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVMA  VSKG AL+AVA+ LG +L++C+AFGDGMND EMLSMAGKG +M ++H+++K 
Sbjct: 192 CLEVMAAEVSKGDALKAVAESLGLTLENCVAFGDGMNDVEMLSMAGKGLVMETSHEKVKK 251

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P+ E+IG+NADDAV HYL+K  L
Sbjct: 252 ALPDNEIIGSNADDAVAHYLQKHLL 276


>UniRef50_Q8KA73 Uncharacterized protein BUsg_029 n=5 Tax=Buchnera aphidicola
           RepID=Y029_BUCAP
          Length = 274

 Score =  248 bits (633), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 121/265 (45%), Positives = 183/265 (69%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A+DLDGTLLSP++ ++ Y ++ +K L  +G  FVFA+GRH++D+ +IRD L IK 
Sbjct: 1   MYRIIAADLDGTLLSPENKITKYTEKIIKFLIEKGFYFVFASGRHYIDIMKIRDTLNIKV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +MITSNGA+V+DL+  LIF ++LD +IA  L  +   + DIIT VYR+++W++N ++ + 
Sbjct: 61  FMITSNGAQVYDLNNVLIFENHLDEEIALKLCKMKYLDADIITQVYRNNQWYINNNKIDN 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                 +  +Y  + P +   + VSKVFFT  + ++L  L++ I +  G+RVNV FS   
Sbjct: 121 NFCPTLSSLRYKYFCPDVFNFKKVSKVFFTSHNLKKLHTLQKDIISFLGNRVNVHFSVPG 180

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV++G VSKG+ L+ ++  LG SLK+CI FGDGMND +MLS++GK CIM +A   LK 
Sbjct: 181 CLEVVSGEVSKGYGLKLISNILGISLKECITFGDGMNDQDMLSISGKACIMENADSSLKK 240

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P  EVIG+N +D V  +L K ++
Sbjct: 241 NLPYAEVIGSNKNDGVAVFLNKNFI 265


>UniRef50_A6FJC9 Putative uncharacterized protein n=1 Tax=Moritella sp. PE36
           RepID=A6FJC9_9GAMM
          Length = 263

 Score =  239 bits (609), Expect = 1e-61,   Method: Compositional matrix adjust.
 Identities = 119/265 (44%), Positives = 167/265 (63%), Gaps = 2/265 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+V+ SDLDGTLL+P H +S   K T+  L  +G  F+ ATGRHHVDV  IR  ++ + 
Sbjct: 1   MYKVIVSDLDGTLLTPAHIVSEQTKITIHKLLKQGKKFIIATGRHHVDVEAIRKTIDAEI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGARVH+  G LI++ N+  DIA  +   +N    I  N++RDDEWF+N   PE 
Sbjct: 61  YLITSNGARVHNHKGELIYSKNIATDIAQ-MITEINLPETIQANIFRDDEWFVNTPNPEV 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           + F +++ F Y + +   L+  G++K FF C  H+ L+ L   INA++  ++NVSFS   
Sbjct: 120 LNFSQDSTFSYQVVDLEALDKAGIAKFFF-CGPHKDLVALAAQINAQYSTQLNVSFSLPE 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM   V+K  AL  V +  G+++ + +AFGDGMND EML    KG +MG+A   LK 
Sbjct: 179 CLEVMDINVNKAQALAEVLRIKGFTMAETVAFGDGMNDVEMLQAVDKGLVMGNASTMLKA 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P+ E+IG +ADD V  Y+ K  L
Sbjct: 239 TLPDFEIIGDSADDGVAQYIEKYIL 263


>UniRef50_A0KR21 Hydrolase, Cof family n=3 Tax=Aeromonadaceae RepID=A0KR21_AERHH
          Length = 270

 Score =  230 bits (587), Expect = 3e-59,   Method: Compositional matrix adjust.
 Identities = 124/264 (46%), Positives = 166/264 (62%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+VV SDLDGTLL+  H +SP  ++TL  L  +GI FV ATGRHHVDV  IRD L +  
Sbjct: 1   MYKVVVSDLDGTLLNGQHQISPRTRDTLHRLVDQGIKFVVATGRHHVDVRSIRDTLGLDI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGA VHD    LIF   L   +A++L  +  D P I  N+Y  DEW +    P  
Sbjct: 61  YLITSNGAVVHDKQDQLIFNQALPDGVAAELIALERD-PSIHINLYYGDEWLVEEEMPWL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++F  E+ F Y L +      + V+KVF+  + HE+LL +E  +N R+GDR+NV+FS   
Sbjct: 120 LQFHHESGFSYRLTDLASHPLDKVNKVFYIGE-HEKLLQIEAELNQRYGDRLNVTFSLPD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM  GV KG+A+ AV ++ G  +   +AFGDGMND EMLSM G+G +MG+AH RLK 
Sbjct: 179 CLEVMHAGVHKGNAVRAVLEQHGLEMSQAVAFGDGMNDFEMLSMVGRGVVMGNAHDRLKL 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                E   ++ +D V  YL +L+
Sbjct: 239 ALANHEQTLSSDEDGVAVYLEQLF 262


>UniRef50_P44771 Uncharacterized protein HI0597 n=32 Tax=Pasteurellaceae
           RepID=Y597_HAEIN
          Length = 272

 Score =  226 bits (576), Expect = 6e-58,   Method: Compositional matrix adjust.
 Identities = 115/264 (43%), Positives = 164/264 (62%), Gaps = 1/264 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
           ++ + SDLDGTLL+P+H +     +TL+ L  +G++ + ATGR+H DV  I   +   ++
Sbjct: 5   FRAMVSDLDGTLLTPEHLVGDLTIDTLRALEQKGVDIILATGRNHTDVSSILGKIGAERA 64

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            MITSNGARV DL GNL+++++L  ++  +L+    D   +  N Y+D+ WF N+  P  
Sbjct: 65  VMITSNGARVRDLQGNLLYSNSLPEELVLELYKTPFDTSKVCMNSYQDEGWFTNKDIPAM 124

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            +F KE+ F Y + +       G  KVFF   + E L+ +E  +  ++GD   + +S L 
Sbjct: 125 RQFHKESGFDYNVVDFSKHHGRGTEKVFFIGKTPEDLVEVETYLRDKFGDVTTIVYSALA 184

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM   VSKG AL+ + +   Y LKDCIAFGDGMND EMLS AGKGCIM  A  RLK 
Sbjct: 185 CLEVMNKNVSKGDALKHLLESREYELKDCIAFGDGMNDVEMLSWAGKGCIMKDADIRLKM 244

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
             PELEVIG+N +++V  YLR  +
Sbjct: 245 ACPELEVIGSNKEESVARYLRTQF 268


>UniRef50_C6JR95 Hydrolase n=2 Tax=Fusobacterium RepID=C6JR95_FUSVA
          Length = 266

 Score =  211 bits (538), Expect = 1e-53,   Method: Compositional matrix adjust.
 Identities = 101/265 (38%), Positives = 173/265 (65%), Gaps = 2/265 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ +  DLDGTLL+  HT+S Y ++ +K +T  G+ F  ATGRHH+D  + ++ L + SY
Sbjct: 3   YKAIVCDLDGTLLNSQHTISKYTRDVIKDVTNLGVKFFIATGRHHMDALKFKEMLGLDSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+SNGAR+H+ +  +IF  ++ +++++++F  +N N +I  N+Y+DD WF  +   E  
Sbjct: 63  LISSNGARIHNENNEIIFKGDIPKELSNEIFD-LNINEEIYKNIYKDDFWFSEKPLDEAH 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            + KE+ F Y++ +   L+   V K F+  +  + +  LE  IN ++G+R+N++ S   C
Sbjct: 122 EYHKESGFTYSVRKFSELKNSEVIKFFYINEDEKLIRNLENEINEKFGNRINLTLSLPIC 181

Query: 182 LEVMAGGVSKGHALEAV-AKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           LE+M  G+SKG+A++ +   K   + ++ I+FGDG+ND EML + G+G +MG+ + RLK+
Sbjct: 182 LEIMNKGISKGNAIKDILLPKFKITPEEVISFGDGLNDYEMLDIVGEGLLMGNCNPRLKE 241

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
           L P  +VIG N +D V  YL+K++L
Sbjct: 242 LLPNNKVIGRNDEDGVAEYLKKVFL 266


>UniRef50_C3WDD5 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WDD5_FUSMR
          Length = 265

 Score =  211 bits (537), Expect = 2e-53,   Method: Compositional matrix adjust.
 Identities = 105/264 (39%), Positives = 159/264 (60%), Gaps = 1/264 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ +  DLDGTLL+  H LS   KE +K +   G     ATGRHH+D   I+  L + SY
Sbjct: 3   YEAIVCDLDGTLLNEKHQLSDETKEVIKKVKDTGKKIFIATGRHHLDALAIKKQLGLDSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+SNGAR+HD   N ++  N+D + A+ +  V   N +I  ++Y D +W++  H+ E +
Sbjct: 63  LISSNGARIHDEHNNEVYERNIDEETANFILNV-KCNKEIERHIYTDTKWYVEEHKEEYI 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            F KE+ F Y + +   +  E   K+FF   + E+L  LE+      GD+V+++ S   C
Sbjct: 122 EFHKESGFLYEVKDFSKIVGEKFIKIFFISKNQEELFKLEKYFEEVIGDKVSITLSGPEC 181

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+M   V+KG A++ + +KL   L++ +AFGDG+ND EMLS  GKG +MG+  QRL++ 
Sbjct: 182 LELMTKNVTKGEAVKNIMEKLNIPLENTMAFGDGLNDYEMLSEVGKGLLMGNCAQRLREK 241

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
            P  E+IG N D+ V  YLRK +L
Sbjct: 242 LPNNEMIGKNIDNGVAKYLRKTFL 265


>UniRef50_A5FGB8 Cof-like hydrolase n=1 Tax=Flavobacterium johnsoniae UW101
           RepID=A5FGB8_FLAJ1
          Length = 281

 Score =  200 bits (509), Expect = 3e-50,   Method: Compositional matrix adjust.
 Identities = 106/258 (41%), Positives = 154/258 (59%), Gaps = 1/258 (0%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +VV SDLDGTLL+P H +S Y K   + L  +    V ATGRHH+D   I + LE+  Y+
Sbjct: 13  KVVVSDLDGTLLNPQHKISDYTKSIFQELHNQNYLIVVATGRHHLDAMAIIETLEVPVYL 72

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ++SNGAR+H  +   +FA NLD D+      V  D P I   +++++ W  N+       
Sbjct: 73  VSSNGARIHSPNKEELFAFNLDSDVVKAALNVEID-PAITVVLFKENVWQTNKWNERLNS 131

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
           F  E  ++  L +   LE  G  K+FF+CD HE+L+ L+  + A   + ++ +FS  TCL
Sbjct: 132 FQAELKYRPELVDYKKLEDFGAIKIFFSCDDHEKLVKLKDDVLANSSEHLHHAFSLPTCL 191

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           E M   + K  A+E V +K GY+L+  ++FGDG ND +MLS +GKG IMG+A   LK+  
Sbjct: 192 EFMDKSIDKAVAIEQVLEKEGYTLEQAVSFGDGFNDVQMLSASGKGLIMGNAPAVLKETL 251

Query: 243 PELEVIGTNADDAVPHYL 260
           P+LEVI TNA+D V  Y+
Sbjct: 252 PDLEVIKTNAEDGVAKYI 269


>UniRef50_Q4D2M6 Haloacid dehalogenase-like hydrolase, putative n=2 Tax=Trypanosoma
           cruzi RepID=Q4D2M6_TRYCR
          Length = 311

 Score =  198 bits (503), Expect = 2e-49,   Method: Compositional matrix adjust.
 Identities = 112/271 (41%), Positives = 159/271 (58%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
           Y  V +DLDGTLL+  H++S Y  ETL+LL  +GI  +FATGR + DV    +   +   
Sbjct: 38  YLAVVTDLDGTLLNEHHSISEYTAETLRLLKNKGIAIIFATGRAYFDVFHTVEKCGLHGG 97

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPD-------IITNVYRDDEWFM 113
           Y+ITSNGARV D     I  H++D ++ S+L  +  D+ +         TN YR +EW  
Sbjct: 98  YLITSNGARVFDPQRRAIVTHDVDPEVVSELINIKLDDENQDAEDSSFATNFYRHEEWLT 157

Query: 114 NRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
           NR     +  +  + F+Y   +      +GV  VFF  + HE LL +E+ + +R+  +V 
Sbjct: 158 NRGSERMLVAYAGSGFRYKEMDLNTCPHDGVHSVFFLGE-HEVLLRVEKVLESRFQGKVE 216

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
            S S    L+ +  GV+KG+A+  VA+ LG S K+ IAFGDGMND +ML MAGKGC+MG+
Sbjct: 217 HSMSHPLVLDTVRWGVNKGNAMCEVAQLLGISAKEIIAFGDGMNDLKMLQMAGKGCVMGN 276

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           A  RLK+  P LEVIG N +D V   LR ++
Sbjct: 277 AQSRLKEALPHLEVIGCNTEDGVARKLRAVF 307


>UniRef50_A8GAR8 HMP-PP phosphatase n=39 Tax=Enterobacteriaceae RepID=COF_SERP5
          Length = 274

 Score =  192 bits (487), Expect = 1e-47,   Method: Compositional matrix adjust.
 Identities = 109/262 (41%), Positives = 153/262 (58%), Gaps = 3/262 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++ A D+DGTLL+PDH + P     LK L  R +   FATGRH++D   I   L ++ 
Sbjct: 1   MYRLAAFDMDGTLLTPDHRVGPETLAVLKQLVEREMVVTFATGRHYLDAQPIMAQLGLQG 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+IT NG RV+D  G  + A +L  DIA ++    + + D   +V+RD+ W      PEE
Sbjct: 61  YLITGNGTRVYDDRGQQLQATDLPADIAEEVLHT-HWHTDASMHVFRDEGWMTEFAVPEE 119

Query: 121 M-RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
           M R    + F Y L E   L   G SKV F    HE+LL L+  +   +  RV++ FS  
Sbjct: 120 MLRAHHLSGFHYQLTELRRLPAFGNSKVCFA-GPHEELLKLQVQLRRHFAARVDLCFSAY 178

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
            CLEV+  G +KG AL+ +++ LG  + +C+AFGD MND EML+  G G +MG+A  +LK
Sbjct: 179 ECLEVLPLGCNKGSALDMLSRHLGLKMAECMAFGDAMNDKEMLATVGHGVVMGNALPQLK 238

Query: 240 DLHPELEVIGTNADDAVPHYLR 261
            L P+L+VIG     AV HYL+
Sbjct: 239 SLLPQLQVIGHCEQQAVAHYLQ 260


>UniRef50_D0A841 Haloacid dehalogenase-like hydrolase, putative n=2 Tax=Trypanosoma
           brucei RepID=D0A841_TRYBG
          Length = 287

 Score =  186 bits (473), Expect = 5e-46,   Method: Compositional matrix adjust.
 Identities = 110/273 (40%), Positives = 160/273 (58%), Gaps = 11/273 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-S 60
           Y+    DLDGTLL+ +H +S Y  +T++ L  R I  V ATGR H DV     +  ++ +
Sbjct: 12  YRAAVVDLDGTLLNENHRISAYTLDTIQKLLKRNIPVVIATGRPHPDVFHTIKSCGLQGT 71

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDI--------ITNVYRDDEWF 112
           Y+ITSNGARV D   N+I + NL  D+ S+L G+ +   DI          N+++ DEW 
Sbjct: 72  YVITSNGARVSDPQLNVIASFNLSEDVVSELIGLGSSGEDIQDPKEVPYTVNLFQHDEWV 131

Query: 113 MNRHRPEEMRFFKEAVFQYALYEP-GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
            +  R E ++ F  + F Y + +     + +GV ++ F    +   L LE  +  R+  R
Sbjct: 132 TDAAREELLQMFASSGFHYRVVDDLQAHQKDGVHELVFLAQPNTLHL-LEGVVKKRFEGR 190

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           ++V  ST   L+V+    +K  A+  VA+ LG  LKD ++FGDGMND +ML+ AGKG IM
Sbjct: 191 ISVMRSTSITLDVVHHNANKATAMAKVAELLGLELKDIVSFGDGMNDVQMLAAAGKGYIM 250

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G+A QRLKD  P LEVIGTNA+D+V   LR+L+
Sbjct: 251 GNAQQRLKDALPHLEVIGTNAEDSVAKKLRELF 283


>UniRef50_A1V919 HAD hydrolase, IIB family n=56 Tax=Betaproteobacteria
           RepID=A1V919_BURMS
          Length = 273

 Score =  186 bits (472), Expect = 7e-46,   Method: Compositional matrix adjust.
 Identities = 102/266 (38%), Positives = 155/266 (58%), Gaps = 3/266 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ +A+DLDGTLL+ DH L PY  +T++ L   G+ FV ATGRH+ DV  IRD L I+ 
Sbjct: 1   MYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDLLGIRP 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFG--VVNDNPDIITNVYRDDEWFMNRHRP 118
           Y+ITSNGARVH  D   I A ++  D    L    +V  +  +I N++ +D W ++R  P
Sbjct: 61  YLITSNGARVHGPDDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAP 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           + + F +++ F+Y + +    +   ++KV +  +  E L  +   +  R+GD + V++S 
Sbjct: 121 QLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEP-EDLAVVSGNLARRFGDALYVTYSL 179

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
             CLEVM   VSKG AL  V ++LG     C+AFGD MND ++L  AG   +M +A+  L
Sbjct: 180 PDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMNNANPDL 239

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
               P++  IG N +  V  +LR L+
Sbjct: 240 ALRLPKVPRIGNNFEAGVARHLRALF 265


>UniRef50_C3WN06 Hydrolase n=12 Tax=Fusobacterium RepID=C3WN06_9FUSO
          Length = 267

 Score =  183 bits (465), Expect = 4e-45,   Method: Compositional matrix adjust.
 Identities = 96/263 (36%), Positives = 156/263 (59%), Gaps = 2/263 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+  H +S +    +K +   G+ F+ ATGR ++D    RD+LE+KSY
Sbjct: 3   YKLIVCDMDGTLLTSSHKISDHTANIIKKIEDSGVKFMIATGRPYLDARHYRDSLELKSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +ITSNGAR HD D N I   N+ +++   L        DI  N+Y DD+W +       +
Sbjct: 63  LITSNGARAHDEDNNPIVVENIPKELVKRLLN-YKVGKDIHRNIYLDDDWIIEYEIDGLV 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            F KE+ + + + +    + + V+K+FF  ++ E +  LE+ +   + D ++++ S+  C
Sbjct: 122 EFHKESGYGFNIDDLSKYQNQEVAKIFFLGENKE-IEELEKKMKKDFKDELSITVSSPFC 180

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE M  GV+K   L+ V K L    ++ IAFGD MND EMLS+ GK  IMG+A++RL + 
Sbjct: 181 LEFMKKGVNKAETLKKVLKILDIKPEEVIAFGDSMNDYEMLSLVGKPFIMGNANKRLIEA 240

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
            P +EVIG N +D +   L++++
Sbjct: 241 LPNVEVIGNNNEDGIGEKLQEIF 263


>UniRef50_A7ZIK4 HMP-PP phosphatase n=87 Tax=Bacteria RepID=COF_ECO24
          Length = 272

 Score =  178 bits (452), Expect = 2e-43,   Method: Compositional matrix adjust.
 Identities = 101/260 (38%), Positives = 145/260 (55%), Gaps = 2/260 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++ A D+DGTLL PDH L      TL  L  R I   FATGRH +++  I   L + +
Sbjct: 1   MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+IT NG RVH L+G L+   +L  D+A +L      +     +++ DD WF  +  P  
Sbjct: 61  YLITGNGTRVHSLEGELLHRDDLPADVA-ELVLYQQWDTRASMHIFNDDGWFTGKEIPAL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++ F  + F+Y + +   +    V+K+ F C  H+ L  L+  +    G+R ++ FS   
Sbjct: 120 LQAFVYSGFRYQIIDVKKMPLGSVTKICF-CGDHDDLTRLQIQLYEALGERAHLCFSATD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV+  G +KG AL  + + LG SL+DC+AFGD MND EML   G G IMG+A  +L+ 
Sbjct: 179 CLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRA 238

Query: 241 LHPELEVIGTNADDAVPHYL 260
             P L VIG   + AV HYL
Sbjct: 239 ELPHLPVIGHCRNQAVSHYL 258


>UniRef50_A1SZR3 Cof-like hydrolase n=2 Tax=Psychromonas RepID=A1SZR3_PSYIN
          Length = 263

 Score =  177 bits (448), Expect = 4e-43,   Method: Compositional matrix adjust.
 Identities = 93/246 (37%), Positives = 141/246 (57%), Gaps = 2/246 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++  SDLDGTLL PDH +S   +ET++     G  FV ATGRH+++   ++++L I  
Sbjct: 1   MYKIAISDLDGTLLGPDHRISVKTEETIQRWVQSGRKFVIATGRHYIEAKHLQESLNIPI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGAR+H+ +G +I   NL  +IA ++   V  +  +  N++ D  W+ N    E 
Sbjct: 61  YLITSNGARIHNKEGKIIHQQNLPSNIAQEICDTVFSDA-VQINLFTDQNWYANYPLAEL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                +A F     +   L+     K+FF  ++ E L P+   + AR+GD++N++FS   
Sbjct: 120 DGMGLDAGFNCIKADLSKLDKSNTIKIFFYAEA-ELLQPVYDLLAARYGDKINLTFSLTK 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM    +KG A++ V K+    + D IAFGDGMND EML    K  +M +A   LK+
Sbjct: 179 CLEVMCANTNKGEAVKVVLKRKSLEISDAIAFGDGMNDLEMLLAVAKPIVMANAQYALKE 238

Query: 241 LHPELE 246
             P +E
Sbjct: 239 ALPNVE 244


>UniRef50_A6T5I9 HMP-PP phosphatase n=18 Tax=Bacteria RepID=COF_KLEP7
          Length = 272

 Score =  175 bits (444), Expect = 1e-42,   Method: Compositional matrix adjust.
 Identities = 96/260 (36%), Positives = 146/260 (56%), Gaps = 2/260 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++ A D+DGTLL PDH L       LK L  R I   FATGRH +++  +     + +
Sbjct: 1   MAKLAAFDMDGTLLMPDHRLGEKTLSALKRLRERDITLTFATGRHVLEMHHVIGEFSLDA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +++T NG R+H L+G  ++  +L  + A  +     D    + +V+ D  WF  + RPE 
Sbjct: 61  FLVTGNGTRIHSLEGEELYRQDLAPEAAEAVLHGKWDTQASM-HVFNDGGWFTGQARPEL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++    + F Y L +   +  + V+K+ F C  H+ L  L   +N   GDR  + FS + 
Sbjct: 120 LQAHVFSGFHYQLCDLKRMSAQHVTKICF-CGDHDDLRRLRIQLNETLGDRAFLCFSAMD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV+  G +KG AL  +++ LG++L++C+AFGD MND EML   G+G IMG+A  +LK 
Sbjct: 179 CLEVLPVGCNKGAALAVLSQHLGFTLQECMAFGDAMNDREMLGSVGRGFIMGNAMPQLKA 238

Query: 241 LHPELEVIGTNADDAVPHYL 260
             P L VIG   + AV H+L
Sbjct: 239 ELPHLPVIGDCRNQAVSHFL 258


>UniRef50_Q7N6X1 Similar to unknown protein n=2 Tax=Photorhabdus RepID=Q7N6X1_PHOLL
          Length = 275

 Score =  174 bits (442), Expect = 2e-42,   Method: Compositional matrix adjust.
 Identities = 100/264 (37%), Positives = 145/264 (54%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY ++A+DLDGTLL  +  +  + ++ L  L++ G   VFATGRHH DV  I  + +I  
Sbjct: 9   MYNLIATDLDGTLLLQEDIIGKFTRKVLTDLSSMGKQIVFATGRHHADVNSIIGDFDIPV 68

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++ITSNGAR+     NL    +L   I   +      + D++ N+Y   +W  N      
Sbjct: 69  HLITSNGARLTSACKNLDIRQHLPSHIVKRVIEETQVDNDLVINMYCGSQWLTNEVNHNF 128

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDS--HEQLLPLEQAINARWGDRVNVSFST 178
             F +   F         +  + V KVFF   S  H+ L+ LE+ +   + D V+++FS 
Sbjct: 129 SDFSQNDNFNPTFKCVDEMPCDAVEKVFFIHKSRNHDALVKLERHLIDLFSDNVSIAFSF 188

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LEVM  GVSKG AL  +A  LG  +   IAFGDGMND EMLS   KG IMG+AH R+
Sbjct: 189 PWSLEVMGSGVSKGQALIQLAGFLGIPMNKTIAFGDGMNDVEMLSTVAKGVIMGTAHNRV 248

Query: 239 KDLHPELEVIGTNADDAVPHYLRK 262
           K   P+ ++IG+  +++V HYL +
Sbjct: 249 KQALPDADIIGSCCEESVAHYLSE 272


>UniRef50_Q4DMD3 Haloacid dehalogenase hydrolase, putative n=2 Tax=Trypanosoma cruzi
           RepID=Q4DMD3_TRYCR
          Length = 326

 Score =  170 bits (430), Expect = 6e-41,   Method: Compositional matrix adjust.
 Identities = 109/295 (36%), Positives = 164/295 (55%), Gaps = 38/295 (12%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL----EIK 59
           VVA+D+DGT+L P H L+   K+TL  L+ RG++ +FATGRHH  V   R +L      +
Sbjct: 31  VVATDMDGTILDPKHRLTERTKDTLYELSTRGVHIIFATGRHHSCVYATRRDLLEHYRRR 90

Query: 60  S----------------YMITSNGARVHDLDGNLIFAHNLDRDIASDL---FGVVN--DN 98
           S                Y+I+SNGARVH+ +G+LIF  +LD DI   L   FG+ +  D+
Sbjct: 91  STARGVPDSPTTGYEGFYIISSNGARVHNPNGDLIFLRDLDSDIVRVLYERFGIRDHGDD 150

Query: 99  PDIITNV--YRDDEWFMNRHRPEEMRFFKEAVFQYALY---EPGLLE---PEGVSKVFFT 150
           P  + +V  Y+ ++W++NR    +    +E++  + +     P LL+     GV KV F 
Sbjct: 151 PRKVLSVSAYQTEKWWINRTIMSD----EESLAMFGVVPDLHPDLLKEFPTTGVGKVCFR 206

Query: 151 CDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSL-KDC 209
           C   + L   E  I   +  R     S+  CL+VMA GVSK  AL  + + L +   ++ 
Sbjct: 207 CYDRDILHQYEAEIKELFHGRATAVMSSEICLDVMAAGVSKAAALREIGRILKFDPEREA 266

Query: 210 IAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           IAFGD MND +ML    KGCIMG+   RLK+  P LEV+G++++D V   L++++
Sbjct: 267 IAFGDSMNDGDMLCSVAKGCIMGNGQSRLKESLPHLEVVGSSSEDGVARKLQEVF 321


>UniRef50_A4HGI1 Putative uncharacterized protein n=4 Tax=Leishmania
           RepID=A4HGI1_LEIBR
          Length = 414

 Score =  167 bits (424), Expect = 3e-40,   Method: Compositional matrix adjust.
 Identities = 110/320 (34%), Positives = 165/320 (51%), Gaps = 57/320 (17%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTA-RGINFVFATGRHHVDVGQIRDNLE--- 57
           ++ VASD+DGT+LSP HTLS Y  ETL+ LT  R + F+FATGR + DV  +  N++   
Sbjct: 92  FRFVASDMDGTILSPHHTLSEYTAETLRRLTQDRNVAFIFATGRVYADVAIVNQNMQRFF 151

Query: 58  -----------------IKSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNP 99
                               Y+ITSNGA VH+ + G L+  H LD  +  +++ ++  + 
Sbjct: 152 RERRQQLHPVPTTTGARTPIYIITSNGAVVHNAETGELVLEHALDPVVVREIYHLLPASE 211

Query: 100 DII-TNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYE--PGLLEPEG------------- 143
             I T + + D WF  R+  E + F KE+ ++Y + E  P  ++  G             
Sbjct: 212 TRINTGIIQGDHWFYRRNWEEMLEFHKESGYRYQVLEFIPDSVDKSGIDTDTLVGSPSAL 271

Query: 144 ------VSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEA 197
                 V KVFF+      L  LEQ +  R+G  + V+FS    L++ A  V+K  ALE 
Sbjct: 272 SGCLKHVHKVFFSSWDLSLLEKLEQTLQQRYGSDLTVTFSASYNLDITAKDVTKAWALER 331

Query: 198 VAKKLG-------------YSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPE 244
           + +++                LK  +AFGD +NDA MLS AG+  IMG+ + +L+   P 
Sbjct: 332 LYEQMAPLPHETRSTVTPEQRLKATVAFGDNLNDATMLSSAGRSFIMGNCNPKLRQRCPN 391

Query: 245 LEVIGTNADDAVPHYLRKLY 264
           LEVI TNA+DAV   LR+++
Sbjct: 392 LEVIQTNAEDAVARKLREIF 411


>UniRef50_Q4Q8C9 Haloacid dehalogenase-like hydrolase, putative n=5
           Tax=Trypanosomatidae RepID=Q4Q8C9_LEIMA
          Length = 284

 Score =  165 bits (417), Expect = 2e-39,   Method: Compositional matrix adjust.
 Identities = 103/279 (36%), Positives = 150/279 (53%), Gaps = 17/279 (6%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDV-GQIRDNLEIKSY 61
           + V +DLDGTLL P H +S YA E LK +  +GI F+ ATGR + +V  +IR       Y
Sbjct: 7   KAVVTDLDGTLLDPQHCISNYAAEVLKKIKEKGICFIVATGRPYAEVFNRIRHCHLAPDY 66

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGV--VNDNP-------DIITNVYRDDEWF 112
           +ITSNGAR+HD   N++  HNL  ++   L  V  V D            TN+YR  EW 
Sbjct: 67  IITSNGARIHDGAFNVVREHNLRPELVESLARVRTVKDPATGAELPKKFTTNIYRGAEWL 126

Query: 113 MNRHRPEEMRFFKEAVFQYA-----LYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
            ++  PE  + F    FQ        YE    E   V +++F  D H++L+ L+ A+  +
Sbjct: 127 TDKSIPEVSKAF-HTDFQCTDLRERFYELQASELGDVHEIWFAGD-HDELVLLDNALREK 184

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
           +   +  +FS    L+ +  GV+KG+ +   A+ LG +L +   FGDGMND  ML +   
Sbjct: 185 YPGDLCCTFSLPHLLDCVPAGVNKGNGVREAAEMLGLALDEVACFGDGMNDESMLQVTST 244

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             IM +A QRLKD  P  ++IG+NADD V   L +++ S
Sbjct: 245 SFIMANAQQRLKDAVPHAQIIGSNADDGVAKKLEEMFFS 283


>UniRef50_D1AMP5 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepID=D1AMP5_SEBTE
          Length = 265

 Score =  164 bits (414), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 99/270 (36%), Positives = 152/270 (56%), Gaps = 10/270 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V +DLDGTLL+ +  +S ++KE +  +  +G+ F  ATGR + D  +I + + IK 
Sbjct: 1   MYRAVVTDLDGTLLNNEKEVSEFSKEVINKIREKGVKFFIATGRSYPDTKRIMETIGIKV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGV--VNDNPDIITNVYRDDEWFMNRHRP 118
            +ITSNGAR++D +G  I+A++L++     +  +       +I  N+Y D+ W++     
Sbjct: 61  PLITSNGARINDENGETIYANDLEKKYIRKILEMDYKKYGEEIFLNLYSDNVWYIT---- 116

Query: 119 EEMRFFKEAVFQYALYEPGLLEPE---GVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           EEM        +Y L     +E      VSK FF  D HE L+ LE+ +       VN++
Sbjct: 117 EEMTMDPFKDLKYFLPHKITVEEAKQMSVSKFFFIGD-HEHLMRLEKELFLLTDGNVNIA 175

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
             T  CLEV    V KG+A++ + KK    + + +AFGDG ND EML M GKG +MG+A 
Sbjct: 176 MVTPECLEVFDIEVHKGNAIKILMKKEKIKMSEVVAFGDGFNDYEMLKMVGKGYVMGNAL 235

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +LK+  P+ E+IGT   DA    L +L+L
Sbjct: 236 YQLKEALPDNEIIGTCDSDAEAKKLIELFL 265


>UniRef50_C6K3T4 Haloacid dehalogenase-like hydrolase-like protein n=2
           Tax=Trypanosomatidae RepID=C6K3T4_9TRYP
          Length = 373

 Score =  159 bits (401), Expect = 1e-37,   Method: Compositional matrix adjust.
 Identities = 114/362 (31%), Positives = 162/362 (44%), Gaps = 99/362 (27%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTAR-GINFVFATGRHHVDVGQIRDNLEI-- 58
           +++VASD+DGTLL+  H ++PY  ETL  L+ R  + F+FATGRHH+ V    + L    
Sbjct: 8   FRIVASDMDGTLLNSAHKITPYTMETLFQLSVRFNVKFIFATGRHHLSVHDAWEALSTYF 67

Query: 59  -----------------------KS-----YMITSNGARVHDLDGNLIFAHNLDRDIASD 90
                                  KS     +++TSNGAR+HD  G LI  HNLD +I   
Sbjct: 68  AQRYEEYHAEQIAAAESSGKTPEKSAAPGFFLVTSNGARIHDPQGKLIVQHNLDPEIVRA 127

Query: 91  LF------GVVNDNPD---------------------------------------IITNV 105
           L+            PD                                       + T+ 
Sbjct: 128 LYLQYGLPYTARHGPDAQKEHAIGSSPYLAQPPTPVPEDAEVGAREGDDEHPEETVSTST 187

Query: 106 YRDDEWFMN---RHRPEEMRFF--KEAVFQYALYEPG--------LLEPEGVSKVFFTCD 152
           Y  D W++       PE  + F  +  V  +   +P             E V KV F C 
Sbjct: 188 YTTDAWYITVPFMPLPEMEKKFGVRPFVVPFDAADPANATRSVFDEFPLEDVGKVCFRCS 247

Query: 153 SHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLG--------- 203
               L  +E  I  ++GDRV+V+ S+  CL+VMA G+SK  AL+ V   L          
Sbjct: 248 DKHILDRMEHNIKLQFGDRVSVALSSTCCLDVMASGISKASALKEVVSLLSSQAATHDTR 307

Query: 204 -YSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRK 262
            +++ D I+FGD MND EML+ AGKGC+M +A +RLK   P+ EVI TN  + V   LR+
Sbjct: 308 VFTMDDVISFGDSMNDEEMLAAAGKGCVMRNAQERLKKCLPQCEVIRTNEQNGVAVKLRE 367

Query: 263 LY 264
           ++
Sbjct: 368 IF 369


>UniRef50_C3WDI3 Hydrolase n=2 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WDI3_FUSMR
          Length = 267

 Score =  155 bits (393), Expect = 9e-37,   Method: Compositional matrix adjust.
 Identities = 85/265 (32%), Positives = 146/265 (55%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V SDLDGTLL+  H +S Y   T++ L  +GI FV ATGRH+ D     + + +  Y
Sbjct: 3   YKIVVSDLDGTLLNSQHRISDYTVSTIRKLEKKGIKFVIATGRHYEDAKYFFNQIGVAKY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGV-VNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I+ NG+ +H  + N I   ++DR +   L  + V +      ++Y+  +W+ +R   + 
Sbjct: 63  LISGNGSFIHSENWNEIGRESIDRKLIKTLLELEVEEGTS--RSIYKGKDWYTDRIVQDY 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAI-NARWGDRVNVSFSTL 179
           + F KE+ +   +      +     K+FF   + + +  LE+ + N      +N++ S  
Sbjct: 121 IDFHKESKYSPQISNLDKFKNVEAEKIFFINPNRKVIEKLEKKMKNLELDKYLNIATSQP 180

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           TCLE+M+   +KG AL+ + K      K+ I+FG  +ND EML  +G G IMG+  +RLK
Sbjct: 181 TCLEIMSKKANKGEALKTLLKYENIDFKEIISFGAALNDKEMLENSGMGIIMGNGDKRLK 240

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
           ++  E +VIG++ +DA   +L  L+
Sbjct: 241 EILKECKVIGSSDEDAAAKFLENLF 265


>UniRef50_Q4Q8D1 Haloacid dehalogenase-like hydrolase-like protein n=3
           Tax=Leishmania RepID=Q4Q8D1_LEIMA
          Length = 333

 Score =  154 bits (388), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 109/326 (33%), Positives = 167/326 (51%), Gaps = 64/326 (19%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLT-ARGINFVFATGRHHVDVGQIRDNLEIK- 59
           ++ V +D+DGTLLSPDH +S Y ++TLK L    G+  + ATGR + DV  I DNL+   
Sbjct: 5   FRYVITDMDGTLLSPDHFVSDYTRDTLKTLVHEHGVIPILATGRSYADVRIIADNLKAYI 64

Query: 60  ---------------------SYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVND 97
                                 Y+ITSNGA VH+ +   ++F  ++D  +A  L  ++  
Sbjct: 65  WCDGTAAPGARAPASPSRAPVIYLITSNGATVHNGVTHEVVFRTSIDPALAEKLLQLLPS 124

Query: 98  NPDII-TNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPE-------------- 142
           + +++ TN Y++D+W      P+ M   KE+  ++ ++ P  L                 
Sbjct: 125 DEEVVNTNAYQNDDWVCRIDWPKMMAVSKESGIRF-IHVPHPLPSSSCALGSAAASPDAA 183

Query: 143 ----------GVSKVFFTCDSHEQLLPLEQAIN----ARWGDRVNVSFSTLTCLEVMAGG 188
                     G+SK+FF  D   +L  L   ++    A  G  V+++FS   C+++MA G
Sbjct: 184 ARGIAIGDYTGISKIFFITDDAARLAALADEVHAIAKAHGGAPVSLTFSMSDCMDIMANG 243

Query: 189 VSKGHALEAV----------AKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
           V+KG AL+ +             +  +L   IAFGDG+NDAEML+  GKGC+MG+A+ +L
Sbjct: 244 VTKGEALKRLFGAILPSRDGVDVVADALAHAIAFGDGLNDAEMLASVGKGCVMGNANPKL 303

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
              HPELEVI TNA+D V   LR  +
Sbjct: 304 IAQHPELEVILTNAEDGVAKKLRSAF 329


>UniRef50_C7ND82 Cof-like hydrolase n=4 Tax=Leptotrichia RepID=C7ND82_LEPBD
          Length = 270

 Score =  150 bits (378), Expect = 6e-35,   Method: Compositional matrix adjust.
 Identities = 87/275 (31%), Positives = 148/275 (53%), Gaps = 18/275 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M++ + SDLDGTLL+ +H +S + +ET+KLL  +GI F  ATGR+++   +  D L +K 
Sbjct: 1   MFKAIVSDLDGTLLNAEHKVSEFTRETVKLLLQKGIKFYIATGRNYLGAKEAMDELGVKI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVND--NPDIITNVYRDDEWFMNR--- 115
            +ITS+G+   D +GN IF++ L R+    +  +       DII   Y    WF+     
Sbjct: 61  PLITSHGSAAFDENGNEIFSNRLKREYLDKVLNIDYKAFGKDIIITGYSGPNWFVTEDLR 120

Query: 116 -----HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
                 +P+  R+ K+         P   +    +K+FF  + H++LL LE  I    G+
Sbjct: 121 EYFYNKKPDRTRYPKQIT-------PSEFKKHDFAKIFFLGEDHDELLELENEIKKVIGE 173

Query: 171 R-VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
             +++ F+    LEV     +K  A E V ++ G +LKD ++FGDG+ND E+++  G G 
Sbjct: 174 ENISLLFANEGSLEVFPADCNKAKAAEVVLERDGLTLKDAVSFGDGLNDYELITETGLGF 233

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            M ++   L +   + EVI +NA+D +   +R+++
Sbjct: 234 AMENSIYLLLEKLTDTEVIESNANDGMAKKVREIF 268


>UniRef50_D1AWH0 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepID=D1AWH0_STRM9
          Length = 269

 Score =  148 bits (374), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 94/271 (34%), Positives = 146/271 (53%), Gaps = 11/271 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V +DLDGTLL+  H +S Y+K+ +K    +G  F  ATGR H    +I D++ +K 
Sbjct: 1   MYKAVVTDLDGTLLNSSHKVSEYSKKVIKKFVEKGYKFYIATGRLHASTKEIADSIGVKI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLD----RDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
            +IT NG R+ D +GN I+ + L     + IAS  +    +  D++ N Y  + W +   
Sbjct: 61  PLITVNGTRILDENGNEIYNNTLSFETVKKIASLDYKSCGE--DLLINGYFRNVWLVTDK 118

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFT---CDSHEQLLPLEQAINARWGDRVN 173
           + EE  ++++       +   + E E +SK F       +HE LL L + I     + +N
Sbjct: 119 KAEE--YYRKERPDKPYFPNTVSEEEFMSKTFNKMHFIGNHESLLKLREKILKEIDEDLN 176

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V F   TCLE+     +K  A + V +K G  L + IAFGD +ND EML   GKG +MG+
Sbjct: 177 VVFVGNTCLEIFNKDANKAKAAKFVLEKDGIKLSEAIAFGDSLNDYEMLKEVGKGFLMGN 236

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           A   LK++ PELE+I TN +D     + +++
Sbjct: 237 AIYLLKEMAPELEIIETNDNDGEAKKIEEIF 267


>UniRef50_C7ND81 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7ND81_LEPBD
          Length = 274

 Score =  147 bits (372), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 99/272 (36%), Positives = 155/272 (56%), Gaps = 11/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V SDLDGTLLS  H ++ + K  +K +   GI F  A+GR +  +G + + LE+K 
Sbjct: 1   MYKAVISDLDGTLLSRGHHVTKFTKNVIKKIIKNGIKFYIASGRSYDQIGYVTEQLEVKI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIIT----NVYRDDEWFMNRH 116
            +I +NGAR+ D DGN+I+   L       + G+  D  +I      N++  ++W + + 
Sbjct: 61  PIIAANGARIFDADGNMIYEKGLSSKAEKAILGL--DYENIAEGSHLNIFSGNDWIITKG 118

Query: 117 RPEEM--RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
             +++  R  ++    +       LE   + K+F+  D HEQL  LE+AI  +  D VNV
Sbjct: 119 TAQKVYDRISRDVKVDFKEVPKDELENLDILKIFYIGD-HEQLTNLEKAI-LKITDDVNV 176

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
            F +  C+E+MA G +KG A + + ++ G  LKD +AFGDG ND EML+M GKG  MG++
Sbjct: 177 IFVSDYCMEIMAKGANKGAAAKFLLEREGLELKDAVAFGDGENDFEMLTMVGKGYAMGNS 236

Query: 235 HQRLKDLHP-ELEVIGTNADDAVPHYLRKLYL 265
             RL+ L P + E +G N +D     L++L+L
Sbjct: 237 IDRLRKLLPKDFEYVGANTEDGEAVKLQELFL 268


>UniRef50_Q1QY75 Cof protein n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QY75_CHRSD
          Length = 266

 Score =  147 bits (371), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 90/265 (33%), Positives = 141/265 (53%), Gaps = 8/265 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
            ++ +DLD TLL+ +H L     ET + L ARG +   A+GRH  D+   R  L + +Y+
Sbjct: 4   HLIVTDLDNTLLNAEHDLDELTIETFQALAARGHHLALASGRHFHDITAFRRRLGVPAYI 63

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP---DIITNVYRDDEWFMNRHRPE 119
           +++NGA ++  D +LI     ++ + ++L   + + P   DI  N+Y  +EW ++   PE
Sbjct: 64  MSTNGAHLYGPDDSLI----AEQWVPAELVRALVELPRGADIRLNLYTGEEWLIDASAPE 119

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
                    F Y + +    +  GV KV    D  E L  LEQ+I    G R+++++S  
Sbjct: 120 LKALHAHTGFHYRVADLEAHDGRGVGKVLCIGDP-EALAALEQSITETLGTRLHMTYSMA 178

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             LE+MA GV+KG  LE +   LG     C+AFGD +NDAEML++AG G +M +AH  L 
Sbjct: 179 HSLEIMAEGVNKGATLERLLAHLGLPAARCLAFGDNLNDAEMLALAGHGFVMENAHPDLP 238

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
              P+   IG +  + V   LR  +
Sbjct: 239 RRVPDAIRIGHHHPNGVAWQLRDFF 263


>UniRef50_Q7NXV0 Putative uncharacterized protein n=1 Tax=Chromobacterium violaceum
           RepID=Q7NXV0_CHRVO
          Length = 269

 Score =  142 bits (359), Expect = 9e-33,   Method: Compositional matrix adjust.
 Identities = 98/265 (36%), Positives = 137/265 (51%), Gaps = 13/265 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ SDLDGTLL  D  L+   +  L+   ARG+    ATGRH   V ++         +
Sbjct: 12  RLIVSDLDGTLLDKDARLADETRAALQAAVARGVALAVATGRHERQVRKLWPRDLPPVPV 71

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITN----VYRDDEWFMNRHRP 118
           I++NGAR+H  DG L+    L   + + L       P++I      VYRDD   M  H  
Sbjct: 72  ISANGARIHLADGTLLHQSRLSPALLARLL-----RPELIRETELGVYRDD-CIMAYHSR 125

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
            E   +   V +  + +    + E VSKV F C + EQL  +E  I    GD V++++S 
Sbjct: 126 REYSHYTGEVTE--IEDLAGFKAEDVSKVIF-CGTPEQLKAVEADIARELGDEVSMTYSH 182

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
           +  LEVMA GV KG AL  +   L  + +DC AFGD +NDAEML++AG   +MG+AH  L
Sbjct: 183 ICYLEVMAPGVHKGSALRRLLDHLDIAAEDCAAFGDNLNDAEMLALAGLPHVMGNAHPEL 242

Query: 239 KDLHPELEVIGTNADDAVPHYLRKL 263
           K   P   VIG +    V   LR L
Sbjct: 243 KRRLPGAPVIGDHDQAGVARQLRAL 267


>UniRef50_C6K3T2 Haloacid dehalogenase-like hydrolase-like protein n=1 Tax=Crithidia
           sp. ATCC 30255 RepID=C6K3T2_9TRYP
          Length = 292

 Score =  139 bits (349), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 95/289 (32%), Positives = 148/289 (51%), Gaps = 26/289 (8%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDV-GQIRDNLEIKSY 61
           + V  D+DGTLL+P+H +S Y  + L+ +  + I F+ ATGR + +V   IR       Y
Sbjct: 4   KAVFVDMDGTLLNPNHEISDYTADVLRRVKEKKIRFIVATGRPYGEVIATIRRCRLEPDY 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVN-----DNPD---------------I 101
           +ITSNG R+HD   N++  HN+  ++A+ L  + N     D P+               I
Sbjct: 64  VITSNGGRIHDGSFNVVREHNIPVELATQLVKMGNSSAASDAPETTDKAEGKLTNTKKKI 123

Query: 102 ITNVYRDDEWFMNRHRPEEMRFFKEAV----FQYALYEPGLLEPEGVSKVFFTCDSHEQL 157
           +TNVYR  EW  +   PE      + +        LYE    +  GV +V++  ++ + L
Sbjct: 124 VTNVYRHTEWLTDEDVPELSGAMHKNLPCTDLGDRLYELTPQDLVGVHQVWYYGETAD-L 182

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
           + L   +   +G ++  +FS    ++     V+KG+ +  VA  LG +L+D   FGD MN
Sbjct: 183 VVLNDELTRAFGPQLCWTFSAPNMIDCGPVAVTKGNGVREVADVLGLALEDVACFGDAMN 242

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           D  ML +AGK  IM +A   LKD     EVI +NA+D V   L +L+L+
Sbjct: 243 DESMLQIAGKAYIMANAQPSLKDAVEHGEVIESNANDGVAKKLEELFLA 291


>UniRef50_Q384S8 Haloacid dehalogenase hydrolase, putative n=3 Tax=cellular
           organisms RepID=Q384S8_9TRYP
          Length = 312

 Score =  137 bits (346), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 85/291 (29%), Positives = 140/291 (48%), Gaps = 27/291 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL----- 56
           +  V  DLDGT+L  +H +S   K TL  + + G++ + ATGR    V  I   L     
Sbjct: 20  FVAVVVDLDGTILDDNHRVSDVTKATLYEVASCGVHIIIATGRPREGVAAIEQELNSYFR 79

Query: 57  -------------EIKSY-MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVV------- 95
                        E+K + ++ SNGAR+++  G LI A ++D  +   ++  V       
Sbjct: 80  CNSRVPGRATSLAEVKGFHLVASNGARIYNTTGELISAESIDNSVVRAIYERVTESNINA 139

Query: 96  NDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHE 155
           N    ++ +V++   W++N   PEE    K                +GV K+     +  
Sbjct: 140 NSEDSMLVSVHQTGAWWVNNVLPEEWLRRKYGTLPEVRQNLSDFPTDGVGKICLRSFNEG 199

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSL-KDCIAFGD 214
            L   ++ ++ ++   +    ++  CL++M  GVSK  AL  V + L +   +D IAFGD
Sbjct: 200 TLRTFQKELDTKYEHYITTVMTSDHCLDIMPKGVSKASALRMVGEILNFEPHRDAIAFGD 259

Query: 215 GMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +ND +ML    KGCIM +    LK+L P +EV+G N +D V H LR+++L
Sbjct: 260 SLNDRDMLESVAKGCIMKNGKNELKELLPHVEVVGCNEEDGVAHKLREVFL 310


>UniRef50_B9Z762 Cof-like hydrolase n=1 Tax=Lutiella nitroferrum 2002
           RepID=B9Z762_9NEIS
          Length = 268

 Score =  134 bits (338), Expect = 2e-30,   Method: Compositional matrix adjust.
 Identities = 97/260 (37%), Positives = 137/260 (52%), Gaps = 25/260 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY  +ASDLDGTLL    T++P+   TL+   ARG++ + ATGRH  DV  +   LE+  
Sbjct: 1   MYAAIASDLDGTLLDARETITPFTAATLRAAAARGVHLIIATGRHVRDVQHLTAALELPI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII----TNVYRDDEWFMNR- 115
            +ITSNGARVH  DG L+ A ++  +    L       PD+      ++Y D+       
Sbjct: 61  SLITSNGARVHGSDGALLHADDVPAEHVRALL-----QPDLAHGTRLSLYLDEGGLCCLH 115

Query: 116 ----HRPEEMRFFKEA--VFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
               HR  E  F ++   + Q+    PG     GV+K+ +T     +L  +E AI  R+G
Sbjct: 116 DGYVHRDAETGFSQQCDDLSQH----PG----HGVAKLMYTAPP-TRLAEIEAAIRQRFG 166

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
             + +++S    LEVMA GVSKG AL  +  +LG + + C AFGDG+ND EML   G   
Sbjct: 167 SALALTYSRPDYLEVMAPGVSKGRALTRLLARLGVAPERCAAFGDGLNDVEMLQSVGHPF 226

Query: 230 IMGSAHQRLKDLHPELEVIG 249
            M +A  RL  L PE+   G
Sbjct: 227 RMANASPRLSALLPEVAEAG 246


>UniRef50_A4HGI8 Haloacid dehalogenase-like hydrolase-like protein n=6
           Tax=Trypanosomatidae RepID=A4HGI8_LEIBR
          Length = 302

 Score =  134 bits (336), Expect = 4e-30,   Method: Compositional matrix adjust.
 Identities = 90/279 (32%), Positives = 141/279 (50%), Gaps = 16/279 (5%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDV-GQIRDNLEIKSY 61
           + V  DLDGTL +  H +S      ++ L  RG+ F+ ATGR   DV G +        +
Sbjct: 7   KAVFVDLDGTLFNSHHFISLRTATVIQALKERGVAFIVATGRPFPDVFGNLAKANLSPDF 66

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLF---------GVVNDNPD---IITNVYRDD 109
           +ITSNGAR+HD   N +FA +++ +    LF         GVV+       I+ N+   D
Sbjct: 67  IITSNGARIHDARQNTLFAGDINTESVCRLFQLSPHLTDEGVVDPAVQARHILFNINCRD 126

Query: 110 EWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGV--SKVFFTCDSHEQLLPLEQAINAR 167
            WF N    E    F  + F Y   +P     E +  +   +   +H  L+ +++ ++  
Sbjct: 127 RWFTNECVAEVRAAFHPS-FIYEQVDPMTQTTETLKGTHSMWIRGAHADLVCVKKYVDRE 185

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
               V  +F+    L+  A G++KG A+  V   +G +L + IAFGDGMND +ML  AGK
Sbjct: 186 LSHEVTCTFALPHILDCFAKGINKGVAMRTVCTHIGIALSETIAFGDGMNDIQMLVEAGK 245

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           G +MG+A + +K   PEL VI +N ++ V   L +L ++
Sbjct: 246 GFVMGNAAEMVKQAAPELPVIPSNNEEGVAWQLEELLVA 284


>UniRef50_B5RQP7 Uncharacterized conserved protein n=22 Tax=Borrelia
           RepID=B5RQP7_BORRA
          Length = 297

 Score =  127 bits (320), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 88/291 (30%), Positives = 140/291 (48%), Gaps = 40/291 (13%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIR-DNLEIK-S 60
           + V SDLDGTLL  +  +  +++  +K LT     F+ ATGR   ++  +   NL    S
Sbjct: 5   KAVVSDLDGTLLLSNSQIGAFSELVIKKLTKENKKFIIATGRSKNEIIPLLIQNLNSHVS 64

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           + IT NGARV++    LI +++L  DI  ++        +I  N Y+D   F+ R    +
Sbjct: 65  FFITLNGARVYNNQWQLISSYDLAPDIVKEIL-------NIRENKYKDIPHFLQRSDDTD 117

Query: 121 MRFFKEAV-----------------FQYALYE--------------PGLLEPEGVSKVFF 149
              + + +                  QY  +E                +     ++K+  
Sbjct: 118 ENLYADNITKNAINDIFKKHRLLNKHQYIKHELQDINIRYNEVNNFQEIKNFNKIAKILL 177

Query: 150 TCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDC 209
             D   QL+  E  I  ++ ++VN   ST   LE++   VSKG+AL+ V   +  +L + 
Sbjct: 178 LHDEEAQLIKYEATILEKYREKVNAYLSTPHSLEIVNSKVSKGNALKDVLTSININLNET 237

Query: 210 IAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
           IAFGDG ND +ML    KG +MG+A+ RLK +   LE+I TN ++AV HY+
Sbjct: 238 IAFGDGFNDVDMLENVKKGLLMGNANYRLKKMLSYLEIINTNHNEAVAHYI 288


>UniRef50_Q4Q8C8 Haloacid dehalogenase-like hydrolase-like protein n=2
           Tax=Leishmania RepID=Q4Q8C8_LEIMA
          Length = 402

 Score =  124 bits (311), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 77/240 (32%), Positives = 118/240 (49%), Gaps = 34/240 (14%)

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYR----------- 107
           + + ITSNGA +++     I+   +D  +  +L+ +  D+P++  NV+R           
Sbjct: 146 RCFAITSNGACIYNEANERIYERTIDPRLVQELYSMFMDDPEVNINVFRGVDEADRQQQG 205

Query: 108 ------------DDEWFMNRHRPEEMRFFKEAVFQYALYE--PGLLEPEGVSKVFFTCDS 153
                        +EW        E   +KE+ F + +          + VS++FF C +
Sbjct: 206 YTNPSDQPDDKASEEWICRYPSDLEAALYKESRFTFRVVSNLEKAFPVDRVSEIFFLCYN 265

Query: 154 HEQLLPLEQAINARWGD---------RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGY 204
            E+   +E  IN R  +          V V+ S   CL+++   VSK  AL+ V  KL  
Sbjct: 266 PEKSSLVESDINKRMKELADEQKLETSVRVAPSATYCLDIVPSDVSKASALQHVLDKLDL 325

Query: 205 SLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ++ DCIAFGDG+ND E+LS  GKG IMG+ + RLK   P LEVIG N DDAV   L +++
Sbjct: 326 TMNDCIAFGDGLNDLELLSSVGKGFIMGNGNPRLKKKLPHLEVIGQNDDDAVARKLSEIF 385



 Score = 60.8 bits (146), Expect = 5e-08,   Method: Compositional matrix adjust.
 Identities = 31/71 (43%), Positives = 47/71 (66%), Gaps = 2/71 (2%)

Query: 2  YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--K 59
          Y++VA D+DGTLL+ +H++S Y +  L  L ARG++ VFATGR   DV +I+  L I   
Sbjct: 29 YKLVACDMDGTLLNSNHSISDYTRTVLSQLLARGVHIVFATGRPFTDVYRIKRRLNIFAA 88

Query: 60 SYMITSNGARV 70
          + +I + G +V
Sbjct: 89 TKLIPTPGLQV 99


>UniRef50_C6K3T3 Haloacid dehalogenase-like hydrolase-like protein n=1 Tax=Crithidia
           sp. ATCC 30255 RepID=C6K3T3_9TRYP
          Length = 420

 Score =  122 bits (306), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 76/242 (31%), Positives = 119/242 (49%), Gaps = 37/242 (15%)

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYR----------- 107
           + + +TSNGA ++D     I+  ++D  +  +L+ +   +P++  NV+R           
Sbjct: 169 RCFAVTSNGACIYDEANERIYERSIDPRVVHELYSMFMGDPEVNVNVFRGVDAAERQKQG 228

Query: 108 ------------DDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEP---EGVSKVFFTCD 152
                        +EW        E   +KE+ F + +  P + +    + V++VFF C 
Sbjct: 229 YTNPSDQPDDKASEEWICRYPSDLEAALYKESKFVFRVV-PDIEQTYPVDHVNEVFFLCY 287

Query: 153 SHEQLLPLEQAINARWGD----------RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKL 202
           + E+    EQ +                 V V+ ST  CL+V+   VSK  AL+ V   L
Sbjct: 288 NPERCARAEQEVTEHMKKFVDVIGAPEAAVRVAPSTTYCLDVVPANVSKASALQQVINDL 347

Query: 203 GYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRK 262
             + +DCIAFGDG+ND EMLS  GKGC+MG+A+ RLK   P LEV+G N DD V   L +
Sbjct: 348 NLTWEDCIAFGDGLNDVEMLSSVGKGCVMGNANPRLKAKLPHLEVVGLNDDDGVARKLCE 407

Query: 263 LY 264
           ++
Sbjct: 408 VF 409



 Score = 56.6 bits (135), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 26/57 (45%), Positives = 39/57 (68%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI 58
           +++VA DLDGTLL+  H++S + +  L  L ARG++ +FATGR   DV +I+  L I
Sbjct: 54  FKLVACDLDGTLLNSKHSVSDFTRSVLSQLLARGVHVIFATGRPFTDVYRIKRRLNI 110


>UniRef50_C3WAR4 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WAR4_FUSMR
          Length = 260

 Score =  116 bits (290), Expect = 9e-25,   Method: Compositional matrix adjust.
 Identities = 72/262 (27%), Positives = 129/262 (49%), Gaps = 5/262 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           + V SDLDGTLL   + +S Y   T+  L  + +NF  ATGR    V  I   L I  Y+
Sbjct: 2   KFVVSDLDGTLLHSHNIVSEYTIRTIDKLVKKNVNFAIATGRGQQGVQGILKQLGINPYL 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I +NGA ++  +G  I    + + I +++   +  N ++  + + ++ +F ++  P E  
Sbjct: 62  ICNNGANIYTPEGECILDKRIPKKIVTEILKEIRKN-NLFYSAFLNEFYFHSKDEPVE-D 119

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
           F    +F     E     P+ ++K+  + D+ + L+ L   +  ++     +  S  TC+
Sbjct: 120 FTSRPLFTEVAVEKEEDIPD-LNKIIVSDDNPKVLIELVNILKNKFSHLAEIMLSQPTCI 178

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           ++     +KG  +E +A+    +  D +AFGDG ND +ML   G   IM ++ + LKD  
Sbjct: 179 DIAPKNCTKGTGIENLARIFNLTPDDFMAFGDGENDLDMLKTVGHPVIMENSQELLKDFF 238

Query: 243 PELEVIGTNADDAVPHYLRKLY 264
             + +  +N +D V  YL K +
Sbjct: 239 SNVTL--SNKEDGVARYLEKFF 258


>UniRef50_D0Z8V8 Hydrolase, Cof family n=1 Tax=Edwardsiella tarda EIB202
           RepID=D0Z8V8_EDWTE
          Length = 271

 Score =  112 bits (281), Expect = 9e-24,   Method: Compositional matrix adjust.
 Identities = 83/265 (31%), Positives = 127/265 (47%), Gaps = 5/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V +DLDGTLL+P   LS +    LK L+A GI  VFATGRH  D  +I   LE + +
Sbjct: 8   YKAVVTDLDGTLLNPQGQLSTHTLVILKKLSALGITLVFATGRHPRDAQRIAQALEQRPH 67

Query: 62  MITSNGARVHDLDGNLIFA-HNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++  NG+       + I   H + +DI +D+   +     I  + +    W +       
Sbjct: 68  IVGLNGSLTLCQQSDAILCEHVIAQDIIADIMRFIAPY-HIHLSAFDSHGWKLYEVNEMA 126

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             + K + F Y    P  +    ++K+     S   + PLEQ +  ++G  +    +   
Sbjct: 127 NDYVKLSGFSYLQIAPSDIFSLKINKLLLW--STNDIAPLEQRLQQQFGQYLACYRTFAQ 184

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSL-KDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
            LE+   G+SK  A+ A+  + G    +  IAFGDG ND EML  AG G +M +A   LK
Sbjct: 185 QLEIGPRGISKASAVAALLAEKGIDFQRQAIAFGDGHNDTEMLRQAGLGIVMDNAPCELK 244

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
                L V  +NADD V   L+ ++
Sbjct: 245 MQLGTLPVAQSNADDGVAQMLQHIF 269


>UniRef50_Q3D5Y9 Hydrolase, haloacid dehalogenase-like family n=9 Tax=Streptococcus
           agalactiae RepID=Q3D5Y9_STRAG
          Length = 265

 Score =  112 bits (280), Expect = 1e-23,   Method: Compositional matrix adjust.
 Identities = 73/243 (30%), Positives = 129/243 (53%), Gaps = 5/243 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ SD+DGTL++ +  ++P  ++ +K + A+G  FV  + R    +  I + + I S
Sbjct: 1   MVRLIFSDIDGTLINSNFKVTPKTRQGIKQIVAQGATFVPISARMPEAITPIMEQIGIDS 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDN-PDIITNVYRDDEWFMNRHRPE 119
           Y+I+ NGA + D+    I +H +D  +A  +   V+ +   I  NVYR  EW+ +  +  
Sbjct: 61  YIISYNGALIQDMQQKTIASHTMDGQVALQVCSYVSKHYSKIAWNVYRYHEWY-SCDKEN 119

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLL--PLEQAINARWGDRVNVSFS 177
           E    +E +      E  L+E E   ++       E  L   LE  + A++   ++++ S
Sbjct: 120 EWVQKEEEIVGLQSKEMSLMELEKQDRIHKLLLMGEPSLMGELENTLKAQY-PHLSIAQS 178

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               +E+MA G+ KG + + +A  L  SL D IAFGD  ND  +L + GKG +MG+A + 
Sbjct: 179 APYFIEIMAPGIEKGKSAKTLADYLDISLADSIAFGDNYNDLNLLEIVGKGFVMGNAPKD 238

Query: 238 LKD 240
           L++
Sbjct: 239 LQE 241


>UniRef50_D1AJW8 Cof-like hydrolase n=1 Tax=Sebaldella termitidis ATCC 33386
           RepID=D1AJW8_SEBTE
          Length = 262

 Score =  111 bits (277), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 70/239 (29%), Positives = 126/239 (52%), Gaps = 2/239 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + V SDLDGTLL+ + T+S   KE ++ L   GI F  ATGR  + + +  D+LE+ +
Sbjct: 1   MIKAVFSDLDGTLLNENGTVSEETKEMIEKLKKAGIKFFIATGRSFLAMKRFYDHLELDT 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            ++  NGA +H+ DG  IF   LD  +A +L      N ++  + + +++W++  +    
Sbjct: 61  EIVNYNGAVIHNSDGGKIFELTLDDSVARELIDYGRKN-NLYYHGFSNEKWYLEDYNDTA 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             +  ++  Q  +     +     +K+ F  D+ E    ++  +  ++ +++    S+ T
Sbjct: 120 KAYGAKSQLQENIINFDNMPKLDFNKMMFINDA-ETTKIVDSYVIEKYKNKIYKGLSSPT 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
            LE+M   VSKG+A++ + +K G+   + IAFGD  ND EML     G  M +A+  +K
Sbjct: 179 FLEIMNPDVSKGNAVKFLLEKYGFQPDEVIAFGDAENDLEMLFSVKYGVAMENANDEVK 237


>UniRef50_C6JK34 Hydrolase n=2 Tax=Fusobacterium RepID=C6JK34_FUSVA
          Length = 258

 Score =  110 bits (274), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 71/265 (26%), Positives = 134/265 (50%), Gaps = 13/265 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V SDLDGTLL     ++ Y K  +K L   GI F  ATGR      +++ ++ +  Y+
Sbjct: 2   KLVVSDLDGTLLDTKSQITDYTKSIIKKLVNNGIEFAIATGRGPASAIKLKKDIGLDIYL 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I +NGA ++D   N IF   +D+ I+ ++  ++ D   +  N + DD+++  R   ++  
Sbjct: 62  ICNNGANIYDKKENSIFEKVIDKKISQNIIKLLRDRK-VAYNGFIDDDFY--RDEYDKTD 118

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
           + +   F   +   G +E           +  + +L + + +  ++ + V ++ S   C+
Sbjct: 119 YSRRTDFIEHIL--GDIEECPALHKIIIVEEADIILRINKELREKFSNVVEITISDPECI 176

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +++    SKG+AL+ +A++LG  ++  +AFGDG ND +ML   G    M +A   +K   
Sbjct: 177 DIVPKECSKGNALKIIAQQLGIEMERVMAFGDGENDLDMLKKVGHPVAMENAQDIVKK-- 234

Query: 243 PELEVIGT---NADDAVPHYLRKLY 264
              E+  T   N ++ V  YL K +
Sbjct: 235 ---EINNTAPKNIENGVALYLEKFF 256


>UniRef50_Q897B3 Putative haloacid dehalogenase-like hydrolase n=1 Tax=Clostridium
           tetani RepID=Q897B3_CLOTE
          Length = 263

 Score =  109 bits (273), Expect = 9e-23,   Method: Compositional matrix adjust.
 Identities = 69/269 (25%), Positives = 139/269 (51%), Gaps = 12/269 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGTLL+ +H +S    +T+K    +GI  +  +GR +         LE K 
Sbjct: 1   MYKLIALDIDGTLLNREHEISDETIDTIKESMDKGIKIILVSGRDYSAAEPYIKKLETKD 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             +  NGA ++D +G +I +  LD++I   +  +  +  DI   ++ ++  ++N    E 
Sbjct: 61  LFLGLNGANIYDNEGKIIHSEYLDKEIVEYIIELC-EKEDIYIVLFIENNTYVN----EI 115

Query: 121 MRFFKEAVFQYALYEPGLL----EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             F     + +   E G +    + + V+K+  T    E+L+P+++ +++++G ++N  F
Sbjct: 116 SDFMGIDNYVFNSIEVGQISKFYKEQNVTKILLT-HKEEKLIPIKEKLDSKYGSKINSQF 174

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE+  G ++KG AL+ + +K     ++ +A GD  ND  M+  AG G  MG+  +
Sbjct: 175 SLPQFLEIFNGKINKGVALKRICEKYKIPKENVMAIGDWDNDITMIKYAGLGIAMGNGSE 234

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +K+      +  +N ++   + ++K  L
Sbjct: 235 NIKEAAD--FITNSNEENGAAYAIKKFVL 261


>UniRef50_C6CW76 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CW76_PAESJ
          Length = 268

 Score =  108 bits (269), Expect = 2e-22,   Method: Compositional matrix adjust.
 Identities = 76/270 (28%), Positives = 135/270 (50%), Gaps = 10/270 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+D TLL+ D  ++   K+ ++   A G+    ATGR +    +I D +++  
Sbjct: 1   MYKLIAIDVDDTLLNDDLIVTEGTKKAMEDAIALGVTVTLATGRMYASAKKIADQIQLNV 60

Query: 61  YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +IT  G+ V  L DG +++   + +D A +L+ +  +   +   +Y DD  ++     +
Sbjct: 61  PIITYQGSLVKTLLDGEVLYERCVPQDAAKELYAI-TEQRGLHLQLYADDILYVKEANEK 119

Query: 120 EMRFFKEAVFQYAL---YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
            +++       Y +   +E  L +P   +      D    L  L + +    GDRV+++ 
Sbjct: 120 AIKYSTLTNIPYVVAEDFEALLDKP---NNKMLIIDDPAYLDQLAEELKPIIGDRVHITK 176

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE M    +KGHAL  +A+ LG  ++  IA GD  ND EM+  AG G  MG+A  
Sbjct: 177 SKPHYLEFMHKEGTKGHALRFMAEHLGCGVEQTIAIGDAWNDHEMIEAAGLGVAMGNATP 236

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +LK++   + +  TN ++ V H + K  L 
Sbjct: 237 KLKEIADYITL--TNNEEGVRHVIEKFVLQ 264


>UniRef50_A1QZK7 Hydrolase (HAD superfamily) n=8 Tax=Borrelia RepID=A1QZK7_BORT9
          Length = 279

 Score =  107 bits (267), Expect = 4e-22,   Method: Compositional matrix adjust.
 Identities = 85/273 (31%), Positives = 144/273 (52%), Gaps = 17/273 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINF--VFATGRHHVDVG----QIRDN 55
           Y+++  DLDGTLL+ +H ++P    TLK+L     +F  + ATGR   ++     Q++D 
Sbjct: 8   YKMLVFDLDGTLLNNNHEIAPL---TLKVLLRLKNDFHIIVATGRRLYEIKDVLMQLKD- 63

Query: 56  LEI-KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN 114
           L+I +SY++T+NGA +  L  NLI  + ++ DI  +L  V   + DI  N+Y  + W+ +
Sbjct: 64  LQIDESYIVTANGAEIF-LKNNLILRYKINYDIVRELLKVKRGDIDI--NLYTLNNWYSD 120

Query: 115 RH-RPEEMRFFKEAV-FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
           R  R   M +F E +  Q  + +   LE +  SK+ +      +L      I  +    +
Sbjct: 121 REIRSPIMNYFIETLGIQPIITDLSELEIDSCSKIVYYSHDFSKLEDFANKIRDKNFKDI 180

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           ++ +S    LE+     SK +A++++A     S+   +AFGD  ND EML  AGKG +M 
Sbjct: 181 SIFYSANDLLEITNIDASKYNAIKSIALFECISIDAILAFGDNGNDYEMLKNAGKGILMK 240

Query: 233 SAHQRLKDLHPELEVIGTNAD-DAVPHYLRKLY 264
           +A++ +K+     EV   N D D V  +L + +
Sbjct: 241 NANKFVKNNLSNNEVTKFNNDEDGVAKFLIEFF 273


>UniRef50_C2KV90 HAD superfamily hydrolase n=1 Tax=Oribacterium sinus F0268
           RepID=C2KV90_9FIRM
          Length = 270

 Score =  106 bits (264), Expect = 9e-22,   Method: Compositional matrix adjust.
 Identities = 78/280 (27%), Positives = 141/280 (50%), Gaps = 26/280 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M++ +A DLDGTL + +  +S   K  L+    RG++ + A+GR    + ++ + LE++ 
Sbjct: 1   MFKAIALDLDGTLTNSEKKVSERNKRALQEAIKRGVSIILASGRPTYGMSEVWEALELEK 60

Query: 61  ---YMITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVND---------NPDIITNVYR 107
              Y+++ NG+   D     ++F   + R   + +   V +           +I+T   R
Sbjct: 61  LGGYVLSYNGSLCMDCKSKEVLFEKTIPRKYYAPIAQAVREADLGLLSYQGKEIVTE--R 118

Query: 108 DDEWFMNRHRP-EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINA 166
            +  +M+R     +M F K   F  AL E        V K+      HE+LLPL++ +  
Sbjct: 119 PEFPYMDRESTINKMPFRKVEDFPNALSEE-------VCKLL-ALGEHEELLPLKERLEK 170

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
            +G+ +++ FS    LE+   GV KG +L+ + +K G+  ++ +AFGDG ND  ML  AG
Sbjct: 171 EYGEELSIFFSEPFFLEICPVGVDKGESLKRLLEKKGWKREELMAFGDGGNDLTMLQYAG 230

Query: 227 KGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           KG  M ++ + + ++  E+ +  +N +D V   + K  LS
Sbjct: 231 KGIAMANSQKHVLEIADEVTL--SNDEDGVAVMVEKYILS 268


>UniRef50_C6PXU7 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PXU7_9CLOT
          Length = 272

 Score =  103 bits (257), Expect = 6e-21,   Method: Compositional matrix adjust.
 Identities = 76/274 (27%), Positives = 135/274 (49%), Gaps = 15/274 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+    D+DGTLL+    +S   +E LK + + G+  + A+GR  + +      LE+   
Sbjct: 4   YKWCVCDMDGTLLNSQSIISEENEEALKKIKSEGMEVIIASGRTDLMINCFVKQLELTGP 63

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I+SNG  + D+  G ++++  +++  A ++     +N +I   +Y  D+ + N+  P  
Sbjct: 64  VISSNGGLIRDMKTGKILYSKLIEKSAAEEILSYCCEN-NIDFLIYSFDKVYSNKGNPLG 122

Query: 121 MRFFKEAV--FQYALYEPGLLEPE-------GVSKVFFTCDSHEQLLPLEQAINARWGDR 171
           +++ K +   FQ        LE          V K+   C  HE+++ LE+  +     +
Sbjct: 123 IKYEKLSKDPFQKMKVPVEYLENAVRSIKNINVIKILLVCSEHERVIELEKHFSK--NKQ 180

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           +    S    L++MA  VSKG+AL+ +A+ +   LK+ IAFGD  ND EML   G    M
Sbjct: 181 ITAVSSAKGLLDIMAPNVSKGNALKFLAENMDMDLKNVIAFGDNYNDMEMLKCVGMPIAM 240

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +A Q LK L  +  V  +N +  + + + K  L
Sbjct: 241 ENAVQDLK-LQAK-HVTKSNNESGIAYAINKFVL 272


>UniRef50_C6QV31 Cof-like hydrolase n=1 Tax=Geobacillus sp. Y4.1MC1
           RepID=C6QV31_9BACI
          Length = 296

 Score =  102 bits (254), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 84/283 (29%), Positives = 134/283 (47%), Gaps = 26/283 (9%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A DLDGTLL+  + +S    + +K     GI  V ATGR H DV +I  +  I++++I
Sbjct: 6   LMAIDLDGTLLNKHNEISRENIQAMKEAQKNGIEIVVATGRAHFDVQEIFKHTGIRTWII 65

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE---- 119
            +NGA +H  DG L  +  LD+D A ++   + +  +    V+ D   F  +   E    
Sbjct: 66  GANGATIHKPDGQLFLSTPLDKDKAIEILQWL-EQEEYYYEVFSDSAIFTPQKGRELLSI 124

Query: 120 EMRFFKEAVFQYALYE--PGLLEPEGVSKVFFTCDSHEQLLPL------------EQAIN 165
           EM     A  +    E     L+    S   F     E L P             ++ +N
Sbjct: 125 EMDRLISANPELDSEELKSAALKQYSQSGFVFISSYKELLKPSINIYNILVFSFDKEKLN 184

Query: 166 ARWGDRVNVSFSTLTC-----LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAE 220
             W    + +  TL        E+     SKG+AL+ +AK+LG  L   IA GD MND  
Sbjct: 185 RGWNKFQDCNDLTLVTSANYNFELEHIEASKGNALKILAKELGIPLSQTIAIGDSMNDYS 244

Query: 221 MLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           M+S+AGKG  MG+A + +K++  E+ +  +N +  V + + +L
Sbjct: 245 MISIAGKGIAMGNACEEIKNIAKEVTL--SNDEHGVAYVINRL 285


>UniRef50_C0R158 Putative hydrolase n=1 Tax=Brachyspira hyodysenteriae WA1
           RepID=C0R158_BRAHW
          Length = 267

 Score =  102 bits (253), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 73/249 (29%), Positives = 124/249 (49%), Gaps = 15/249 (6%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           Q++A+DLDGTLL+ +H +S Y K  +K  + +GI  + +TGR      +   +L+I + +
Sbjct: 5   QLIATDLDGTLLNNNHQISEYNKNIIKAASKKGIKTILSTGRPTSAAIKFLYDLDIDTEL 64

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRD----DEWFMNRHRP 118
           I+ NGA + D + N+I+  NL+  I  +L  +         N+Y      D W +     
Sbjct: 65  ISFNGAMITDKNSNIIYQENLNPKIGIELINIAKK-----YNIYHQGFLGDRWNIGFFDN 119

Query: 119 EEMRFFKEAVFQYALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
           +   F+  ++ Q   Y  G   +E    SK  F  ++H  L  + + +N  +G+ +  +F
Sbjct: 120 KWTNFYI-SIAQIDNYIIGFDNIEDFSFSKFMFIGENH-ILKNIAEELNRTFGNSIYYAF 177

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LEV +   SK +AL+ +A K   +  + +AFGD  ND EML   G    + +A  
Sbjct: 178 SRPVYLEVHSPNASKANALKYLADKYNINSDNIMAFGDNNNDLEMLEFVGISVAVENAED 237

Query: 237 --RLKDLHP 243
             +LK L+ 
Sbjct: 238 IVKLKSLYT 246


>UniRef50_B9DT57 Putative haloacid dehalogenase-like hydrolase n=2 Tax=Streptococcus
           RepID=B9DT57_STRU0
          Length = 266

 Score =  101 bits (252), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 84/278 (30%), Positives = 125/278 (44%), Gaps = 25/278 (8%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  ++ SD+DGTLL+  H +S   K  +K    +GI FV  + R    +  I  +   + 
Sbjct: 1   MVSIIFSDIDGTLLNDQHEVSSRTKTAIKECLRKGILFVPVSARMPKAIKPITCSFLPEI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDN-PDIITNVYRDDEWFM----NR 115
            +I+ NGA V D  G  I +  +  D+A  +   V +   DI+ N+Y  +EW      N+
Sbjct: 61  PIISYNGAFVQDKTGYPISSSPMPFDVALSICSTVEEQFNDIVWNIYSGEEWISQDRDNK 120

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
               E         Q AL        E +S    +   H+ LL  E    A+       +
Sbjct: 121 WVKREEEIVSVTSIQMAL--------ETISH---SLTIHKLLLMGEPGSIAKAERLFKEN 169

Query: 176 FSTLTC-------LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
           +S L+        LE+MA G++KG A+  +A   G  L D IAFGD  ND +ML   GKG
Sbjct: 170 YSDLSIAQSYPYYLEIMASGITKGKAVTELATSYGVELGDTIAFGDNFNDLDMLQTVGKG 229

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +MG+A   LK L    +V   N  D +   L +  L+
Sbjct: 230 YVMGNAPTDLKSLIG--DVTTDNNHDGIAEVLERTILT 265


>UniRef50_UPI0001BC5F8F HAD superfamily hydrolase n=3 Tax=Fusobacterium RepID=UPI0001BC5F8F
          Length = 258

 Score =  101 bits (251), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 72/262 (27%), Positives = 124/262 (47%), Gaps = 15/262 (5%)

Query: 5   VASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMIT 64
           V SDLDGTLL+ D T+       ++ L  +G  FV ATGR       IR+ L +  YM+ 
Sbjct: 4   VISDLDGTLLNNDRTVGEKTILGVQNLLKKGYPFVIATGRGFASANTIREKLGVPIYMVC 63

Query: 65  SNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFF 124
           +NGA ++   G LIF + +  ++   +   + +   +    +  D +FM  +  E+M+  
Sbjct: 64  NNGATIYSPKGELIFENYIPVEMVKKVTACL-EKYRVDYRGFFQDYYFMPNYGKEDMKRI 122

Query: 125 KEAVFQYALYEPGLLEPEG----VSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           +        Y+  +LE +     + K+     + + L  +++ +    G+ + ++ S+  
Sbjct: 123 E--------YKAVILEKDEDFQILEKILVVDPNTDLLRKIQKELQEEVGEELTITLSSSE 174

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CL++ +   SK   +E VA  L   L+D IAFGD  ND  ML+  GK   M   +   + 
Sbjct: 175 CLDINSKNCSKAAGIEKVATYLQLHLQDAIAFGDSENDFAMLASVGKAVSMKGTYAAQEK 234

Query: 241 LHPELEVIGTNADDAVPHYLRK 262
            +   E   TN +D V  +L K
Sbjct: 235 DYEVTEF--TNHEDGVIRHLEK 254


>UniRef50_A1HSX6 Cof-like hydrolase n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HSX6_9FIRM
          Length = 272

 Score =  101 bits (251), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 77/262 (29%), Positives = 119/262 (45%), Gaps = 4/262 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLD TLL     +S  A+E +    ARG+    ATGR +         L +   +
Sbjct: 4   KLIAVDLDDTLLDNSLAVSARAREAIAQAVARGVTVTVATGRMYRSALPYARQLGLDVPL 63

Query: 63  ITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           IT NGA +   L G ++    L  D+A D+  +       I  VY DD  ++       +
Sbjct: 64  ITYNGALIKAALSGEVLLHRPLAEDVARDVLALSRQQGWYI-QVYLDDVLYVTELNDRAL 122

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            +   A  +       L    G             +L +++ + AR+GDR+    S    
Sbjct: 123 YYETIAGVKAVPIGDRLYSLPGAPTKLLVMAEPADILRIQEEVQARFGDRLYAVVSKPNY 182

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE++   V+KG AL  +A+KLG S  + +A GD  ND +ML  AG G  MG+A QR+K +
Sbjct: 183 LEMVHPAVNKGAALAFLAEKLGISRDEVMAIGDSYNDLDMLEYAGFGVAMGNASQRVKAV 242

Query: 242 HPELEVIGTNADDAVPHYLRKL 263
                V   N +D V   + K+
Sbjct: 243 AQ--AVTRGNDEDGVAEAIEKI 262


>UniRef50_D1AIM0 Cof-like hydrolase n=1 Tax=Sebaldella termitidis ATCC 33386
           RepID=D1AIM0_SEBTE
          Length = 262

 Score =  101 bits (251), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 71/257 (27%), Positives = 126/257 (49%), Gaps = 5/257 (1%)

Query: 8   DLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNG 67
           DLDGT+L  D T+S    + +  L  R IN   +TGR         + L ++   I  NG
Sbjct: 9   DLDGTVLHDDKTISKRLADVVTELKKR-INIYVSTGRSWESASSYVEKLGLEDLAINYNG 67

Query: 68  ARVHDLDGNLIFAHN-LDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKE 126
           AR+ +L    + +   L+ +    L  V  ++  I  N+Y+DD+W++     E   +   
Sbjct: 68  ARIINLKTKEVISEKPLNEETVKKLIAVSREHK-IHLNLYKDDKWYVENAGREAEYYSNL 126

Query: 127 AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMA 186
              ++ L        +  +K  F  + +++L  +++ +  +    V   FS+   +E++ 
Sbjct: 127 TDIKWNLINFDDFMGKKSTKALFVAE-YKRLEEIKEILQKKLSG-VEYVFSSEYYMEILQ 184

Query: 187 GGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELE 246
            GV+KG A++ V ++ G S  + +AFGD  ND EML     G +MG+A + LK++  + +
Sbjct: 185 EGVNKGSAVKKVLEESGVSKDEAMAFGDHWNDKEMLQYVKYGYLMGNAPENLKEVFDKEK 244

Query: 247 VIGTNADDAVPHYLRKL 263
           +I  N +D V   L KL
Sbjct: 245 IIAANNEDGVAQILEKL 261


>UniRef50_C1QE38 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Brachyspira
           murdochii DSM 12563 RepID=C1QE38_9SPIR
          Length = 269

 Score =  100 bits (249), Expect = 5e-20,   Method: Compositional matrix adjust.
 Identities = 72/261 (27%), Positives = 131/261 (50%), Gaps = 6/261 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A+DLDGT L+ +  +S Y K+  + L   GI  + +TGR    + + ++ +   +Y 
Sbjct: 8   KLIATDLDGTFLNNESEISDYNKKVFQYLMNNGIEIILSTGRPFNGMQRYKNMINNDNYS 67

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I  NGA + D +G  I+   +D   +  +  +VN    +  +VY  +++ ++       R
Sbjct: 68  IVFNGAIIADTNGKFIYNKVIDEASSRGVANLVNK-YKVYLHVYSGNKYIVSEPDFYYER 126

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
           + ++      +     ++    SK+ F  +  E+LL L+  I + +   V+ SFS    L
Sbjct: 127 YIEKENITDTIIGLDNVDNFEFSKMVFIGE-REELLRLQSYITSHF--NVHTSFSHTNFL 183

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           EV+A G++KG AL+ +  K G   ++ IAFGD  ND EM+  AG G  M +  + +K   
Sbjct: 184 EVLANGINKGSALKWLCDKKGIKREEIIAFGDNYNDIEMIEYAGVGVAMYNGEEDVK--K 241

Query: 243 PELEVIGTNADDAVPHYLRKL 263
               V  +N ++ V  +L K 
Sbjct: 242 KADYVCLSNDENGVGEFLNKF 262


>UniRef50_C6P8T7 Cof-like hydrolase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6P8T7_CLOTS
          Length = 293

 Score =  100 bits (248), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 80/278 (28%), Positives = 130/278 (46%), Gaps = 20/278 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++VA D+D TLL+ D  +S    E L+     GI  V +TGR +       + L  K Y
Sbjct: 22  YKLVAIDMDDTLLTYDKQISRENLEALQKAHDSGIYVVISTGRIYASAYAYSEFLGFKPY 81

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDN--------------PDIITNVYR 107
           +I SNGA + D   N I+   LD D+ S L  + N+N              P+  +   +
Sbjct: 82  IIASNGAMIRDDKDNEIYKSVLDVDLISYLINLANENDLYYHFYSDKIVYSPESTSKYQK 141

Query: 108 DDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
             EW  NR   E +R   E + +   +    L+   V  V F  DS E++  +   I+  
Sbjct: 142 YGEW--NRLYAETLRVKVEDIPKDIDFTDK-LKDNIVKFVMFDEDS-EKIKRVRDIIDNN 197

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
            GD++  + S    +E++  G++KG+ L  + + LG    + +A GD  ND EM+  AG 
Sbjct: 198 KGDKLETTSSFYNNIEILNKGINKGNGLRILGEYLGVDRSEMVAIGDSENDTEMVEFAGL 257

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G  M +A ++LK       +  +N ++ V + + K  L
Sbjct: 258 GVAMENAIEKLKKTAD--FITKSNMENGVAYVINKFIL 293


>UniRef50_B5YEJ7 Phosphatase YidA, putative n=2 Tax=Dictyoglomus RepID=B5YEJ7_DICT6
          Length = 262

 Score = 98.6 bits (244), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 75/245 (30%), Positives = 122/245 (49%), Gaps = 24/245 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++  +DLDG+++     +S    E + LL    I    ATGR    + +I + L +  
Sbjct: 1   MYKLFITDLDGSIIDESEVISSKNVEAINLLRKNNIEVTIATGRRWSSITKIVEPLNLNI 60

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIIT-NVYRDDEWFMNRHRP 118
            +I  NGA ++D +  + ++   L +   ++   V+++  D I   VY DD+   +    
Sbjct: 61  PVIIYNGAGIYDPVKNSYLYLKYLSKKEVAESLTVISEYWDYIKLGVYWDDKLIED---- 116

Query: 119 EEMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                 KEA+        GLL+   EG+ K+F   +  E+ L   +    +  D +NV F
Sbjct: 117 ------KEAL--------GLLKQNKEGIIKIFI--EGEEKFLKELKNKILQDKDCLNVVF 160

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S+   LE++  GVSKG AL+ + K LG  L++ IA GD  ND EM+  AG G  + +A  
Sbjct: 161 SSYKYLEILPKGVSKGKALKELVKFLGIKLEEVIALGDYDNDEEMIKWAGLGITLENASI 220

Query: 237 RLKDL 241
           RLK +
Sbjct: 221 RLKKV 225


>UniRef50_C6JKA3 HAD-superfamily hydrolase subfamily IIB n=3 Tax=Fusobacterium
           RepID=C6JKA3_FUSVA
          Length = 264

 Score = 98.6 bits (244), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 75/275 (27%), Positives = 132/275 (48%), Gaps = 26/275 (9%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           + VA DLDGTLL+ D  +S   ++ LK L  +G+     TGR +       + L +   +
Sbjct: 4   KAVALDLDGTLLTTDKKISDINRDVLKELEQQGVKIFIVTGRTYHAAKPYAEYLNLGGVV 63

Query: 63  ITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           I+ NGA+V +  +  ++F   L  +   ++  +      +  N+Y+D++W++     +E 
Sbjct: 64  ISYNGAKVVEYRNDRVVFELPLQEEYVKEIIRIAR-KMGVALNLYQDNKWYVEDSSRKE- 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQ-----------LLPLEQAINARWGD 170
                 V +YA  E  L+    + K F++ D++E            L  + + +    G+
Sbjct: 122 ------VLEYAR-ERNLIP---IEKDFYSFDNYEMTKTVFMGTPDILDKVNREVEKVLGN 171

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           +V  + S  T  EV+   V+KG  LE   K  G S ++C AFGD +ND EML++   G  
Sbjct: 172 KVYKAKSMDTLYEVLNREVNKGLVLERTLKTYGISPEECAAFGDAVNDIEMLTVVKYGVA 231

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           MG+A   +K       +  TN ++ V  +L+K + 
Sbjct: 232 MGNAPHEVKSRVN--YITDTNDNNGVAKFLKKFFF 264


>UniRef50_A4XJ23 Cof-like hydrolase n=2 Tax=Clostridia RepID=A4XJ23_CALS8
          Length = 296

 Score = 98.2 bits (243), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 71/244 (29%), Positives = 127/244 (52%), Gaps = 6/244 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++VA+DLD +LLS D  ++P   + ++ L    +  + A+GR +  V +I  +LE   
Sbjct: 31  MIKLVATDLDDSLLSKDLKITPKNLKAIEFLKKNNVILILASGRPYPSVKKIAYDLENFY 90

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            MIT  GA V+D  D   ++   +  + A +L  +  +  +I  ++Y D+ W++     E
Sbjct: 91  PMITYQGALVYDPKDDRKLYGCEIQPNDAKELIRLAKEE-NIHVHIYIDNVWYVEVFN-E 148

Query: 120 EMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
           ++ ++K       +     LE     V+KV F  D HE+L  L++++   +  + N+ FS
Sbjct: 149 KVEYYKNLTGLEPVKVDNFLEFVDRPVTKVLF-FDEHERLRKLKESLPLEFSKKFNIMFS 207

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LE     VSKG+AL+ +A+       + +A GDG ND  M+  AG G  + +A ++
Sbjct: 208 KPFFLEFTDINVSKGNALKFLAQYYNLKRDEIMAIGDGDNDISMIEYAGIGVAVENATEK 267

Query: 238 LKDL 241
           LK++
Sbjct: 268 LKEV 271


>UniRef50_Q4KBY5 Cof-like hydrolase family protein n=8 Tax=Pseudomonas
           RepID=Q4KBY5_PSEF5
          Length = 270

 Score = 98.2 bits (243), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 76/265 (28%), Positives = 120/265 (45%), Gaps = 13/265 (4%)

Query: 7   SDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSN 66
           SD+DGTLL PDH+LSP   + ++ L   G+ F  ATGR    + Q  + L +       N
Sbjct: 11  SDMDGTLLRPDHSLSPRTLDAVRALREAGVAFSLATGRPPRAMLQQIEALGVDLPTAGFN 70

Query: 67  GARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKE 126
           G  +   DG+ +  H++  + A     +    P + T V+ D+EW +       M   ++
Sbjct: 71  GGSIVKPDGSFLARHHVPVEAAVTALLLFEPCPQVETWVFADNEWLLRNLDGALMPLERQ 130

Query: 127 AVFQYALYEPGLLEP-----EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           A+     Y P +++        + K+      H  L+ LE  + A    +   S S    
Sbjct: 131 ALG----YAPKVVDSFEEYLPRIDKIVAASSDHRLLVQLEARLQAATAGQAQASRSQPRF 186

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           L++ A    KG AL  +A+ LG  L+   A GDG ND  M   AG    MG A +R+K  
Sbjct: 187 LDLTALQADKGQALVTLAEYLGVPLERTAALGDGGNDPAMFQRAGLSIAMGQAEERVKR- 245

Query: 242 HPELEVI-GTNADDAVPHYLRKLYL 265
             + +VI G+N +D     + +  L
Sbjct: 246 --QADVITGSNLEDGAAEAIERYIL 268


>UniRef50_C3K9U8 Putative haloacid dehalogenase-like hydrolase n=1 Tax=Pseudomonas
           fluorescens SBW25 RepID=C3K9U8_PSEFS
          Length = 274

 Score = 98.2 bits (243), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 72/266 (27%), Positives = 119/266 (44%), Gaps = 9/266 (3%)

Query: 5   VASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMIT 64
           + SD+DGTLL PDH+LS    + ++ L   G+ F  A+GR    +  + +   I   +  
Sbjct: 12  ILSDVDGTLLHPDHSLSQRTADAVRALREAGVLFSLASGRPPKAMLHLIETFGIDVPVAG 71

Query: 65  SNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM----NRHRPEE 120
            NG  + + DG+++ AH+L  + A     + +  P++   V+ D +W          P E
Sbjct: 72  FNGGTLINPDGSILVAHHLPAEAALVTLALFSAEPEVEVWVFADGDWLRRDPSGPMEPRE 131

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                        +EP L   + V K+     + + L+ LE  +  +      VS S   
Sbjct: 132 ANGLGYGPVVVESFEPYL---DRVDKIVAASHNTQLLVELEARLQPKVQGLAQVSRSQPV 188

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L+V A   +KG AL+ +A  LG  ++   A GDG ND  M  +AG    MG A + +K 
Sbjct: 189 YLDVTAMLANKGEALKTLAAHLGVPMEQTAAIGDGGNDPAMFQVAGLSIAMGQAEETVK- 247

Query: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266
                 V G+N +D     + +  L+
Sbjct: 248 -RQASVVTGSNIEDGAAEAIERFILA 272


>UniRef50_B8DIC3 Hydrolase, Cof family n=18 Tax=Listeria RepID=B8DIC3_LISMH
          Length = 288

 Score = 97.8 bits (242), Expect = 3e-19,   Method: Compositional matrix adjust.
 Identities = 77/265 (29%), Positives = 123/265 (46%), Gaps = 26/265 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +V+ASD+DGTLL+ D  ++    E ++   A+GI+FV  TGR + D   + +   + +
Sbjct: 1   MIKVIASDMDGTLLNSDIEIAQENVEAIEKARAKGIHFVLCTGRMYDDAMGLINKANLYA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVV----------NDNPDIITNVYRDDE 110
             I  NGA + D  G +I  H +DR++A + +  +           D   I T+  R  E
Sbjct: 61  PAICMNGAEIRDEHGKIILQHPIDRNLARNTYNTLTELGMYTEFFTDMGPITTDKARGKE 120

Query: 111 WFMNRHR---PE----------EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQL 157
           + +  H+   P+          E RF  + V +    E  L   +     F +  S + +
Sbjct: 121 FMIEMHKRIHPDVSAETIMDKVEERFESKDVHEIPDVERILGNKDLTILKFISFSSDKDI 180

Query: 158 L-PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGM 216
           L   +Q +       V  SFS    +E+      KG +L+   +KLG +L +  A GD M
Sbjct: 181 LAKAKQKLEKDSELSVTSSFS--DNIEITHREAQKGISLQYYVEKLGVTLDETFAIGDNM 238

Query: 217 NDAEMLSMAGKGCIMGSAHQRLKDL 241
           ND  ML MAG    MG+  + +KDL
Sbjct: 239 NDISMLKMAGYSVAMGNGEEEVKDL 263


>UniRef50_UPI000196CFC2 hypothetical protein CATMIT_02842 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196CFC2
          Length = 262

 Score = 97.8 bits (242), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 72/270 (26%), Positives = 129/270 (47%), Gaps = 14/270 (5%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQ + SD+DGTLL+ DH +SP  ++ +K L    I F+  + R    +  I    +I  
Sbjct: 1   MYQCILSDIDGTLLTDDHHMSPKTRDAIKSL---DIPFLPVSARSPEGIYPILKENDIVC 57

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFMNRHRPE 119
            MI  +G  + D  GN+++ + ++     ++   + +   D   N+Y   +W +     E
Sbjct: 58  PMICFSGGLILDEKGNVLYENGMNYKQTEEVITFIKEKKFDCTINIYSLHDWLV--EDKE 115

Query: 120 EMRFFKEAVFQYALYEPGLLEP----EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           + R  +E     A  + G L        + K+   C+       +E+++  R+    +++
Sbjct: 116 DPRVLREERIVKAEAQKGTLSSLDSSRKIHKLLCMCNPL-YTKEIEKSLKERFP-HCSIA 173

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S+   +E+M  GV+K  A+  +        KD +AFGD  ND EML   G G  MG+A 
Sbjct: 174 CSSDILIEIMNEGVTKADAINHLCDYYSIDKKDIVAFGDNYNDKEMLESVGMGIAMGNAP 233

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +K++    +V  TN  D + + L+KL++
Sbjct: 234 DDIKNI--ARDVTSTNNQDGIFNALQKLHI 261


>UniRef50_Q0TQ35 HAD hydrolase, IIB family n=9 Tax=Clostridium perfringens
           RepID=Q0TQ35_CLOP1
          Length = 276

 Score = 97.4 bits (241), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 83/288 (28%), Positives = 136/288 (47%), Gaps = 39/288 (13%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V  D+DGTLL   H +S   KE LK    +G++   +TGR         + + + + 
Sbjct: 3   YKLVCIDMDGTLLDSHHKVSERNKEALKKAIEKGVHIAISTGRVFPSARIYGNIIGVNAP 62

Query: 62  MITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVN--------DNPDII---TNVYRDD 109
           +I SNG+ + D + + +IF   LDR+    +  ++N        D+ D +   T++  DD
Sbjct: 63  LICSNGSYIKDKNTDEVIFKSTLDRETYFKICDIINKYKFLAYVDSTDGLIADTDIPEDD 122

Query: 110 E-WFMNR--HRPEEMRFFKEAVFQYALYEPG-------LLEPEGVSKVFFTCDSHEQLLP 159
               MN      E+++F+     + A  E G       +++ EG   +    ++ E+   
Sbjct: 123 SHRLMNSWVDEKEKIKFYNCDDLRDAYDEHGEDILKFIIIKQEGGPNIE---EAKEEFEA 179

Query: 160 LEQA--INARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
           LE    + A WG           C+E+M  G SKG A++A+A KLG SL++ I  GD  N
Sbjct: 180 LEGVDLVYASWG----------GCIEIMKKGTSKGSAVKALADKLGISLEEVICIGDSGN 229

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           D  ML  AG   +MG+A   +K+      +  TN +D V   + K  L
Sbjct: 230 DVSMLEEAGLSVVMGNAPDFIKEYGD--YITDTNENDGVAKAIEKFIL 275


>UniRef50_Q8RF49 Hydrolase (HAD superfamily) n=10 Tax=Fusobacterium
           RepID=Q8RF49_FUSNN
          Length = 270

 Score = 97.1 bits (240), Expect = 6e-19,   Method: Compositional matrix adjust.
 Identities = 66/266 (24%), Positives = 128/266 (48%), Gaps = 9/266 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V SDLDGTLL+ D  +S    E +K L   GI F  ATGR      +IR  + ++ Y+
Sbjct: 8   KLVVSDLDGTLLNDDSEVSNETIEMIKKLKENGIEFAIATGRSFNSANKIRKEIGLEIYL 67

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I +NGA +++ +G +I  + +  D+   +   + +N       +  D   +N + P ++ 
Sbjct: 68  ICNNGANIYNKNGKMIKNNIMPADLIRKVINFLTENS---IGYFAFDGSGINFYVPNDIE 124

Query: 123 FFKEAVFQYALYEPGLLEP----EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
              E + ++  +    LE       + K+    +  E++  ++  ++  + + + +  S 
Sbjct: 125 IDAELLNEHIPHYIKNLEDINNLPALEKILIIEEDTERIYEIKDLVHKNFDNELEIVISA 184

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
             CL++   G SK   +E ++++L  + K+ +AFGD  ND +ML   G    M  +    
Sbjct: 185 DDCLDLNIKGCSKRGGVEYISQELKINPKEIMAFGDSGNDYKMLKFVGHPVAMKDSFMSK 244

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           +D   + +   TN +  V  YL+K +
Sbjct: 245 RDFENKTDF--TNDESGVAKYLQKYF 268


>UniRef50_P94592 Uncharacterized phosphatase ywpJ n=7 Tax=Bacillaceae
           RepID=YWPJ_BACSU
          Length = 285

 Score = 96.3 bits (238), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 80/286 (27%), Positives = 135/286 (47%), Gaps = 28/286 (9%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLL+  H +S   +  L+     GI  V +TGR H DV  I + L IK+++
Sbjct: 2   KLIAIDLDGTLLNSKHQVSLENENALRQAQRDGIEVVVSTGRAHFDVMSIFEPLGIKTWV 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE--- 119
           I++NGA +HD +G L     +D+  A D+   + ++ +    V+     +  ++  E   
Sbjct: 62  ISANGAVIHDPEGRLYHHETIDKKRAYDILSWL-ESENYYYEVFTGSAIYTPQNGRELLD 120

Query: 120 -EMRFFKEAVFQYALYE-PGLLEPEGVSKVFFTCDSHEQLLPLEQAIN------------ 165
            E+  F+ A  +  L       E +     F   +S ++L   ++ I+            
Sbjct: 121 VELDRFRSANPEADLSVLKQAAEVQYSQSGFAYINSFQELFEADEPIDFYNILGFSFFKE 180

Query: 166 ---ARWGDRVNVSFSTLTC-----LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
              A W    +    TL        E+ +   SKG AL+ +AK+L   L++  A GD +N
Sbjct: 181 KLEAGWKRYEHAEDLTLVSSAEHNFELSSRKASKGQALKRLAKQLNIPLEETAAVGDSLN 240

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           D  ML  AGKG  MG+A + +K +   + +  TN +  V H ++ L
Sbjct: 241 DKSMLEAAGKGVAMGNAREDIKSIADAVTL--TNDEHGVAHMMKHL 284


>UniRef50_C5D7Z3 Cof-like hydrolase n=1 Tax=Geobacillus sp. WCH70 RepID=C5D7Z3_GEOSW
          Length = 268

 Score = 96.3 bits (238), Expect = 9e-19,   Method: Compositional matrix adjust.
 Identities = 68/248 (27%), Positives = 121/248 (48%), Gaps = 17/248 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ SDLDGTLL  D+ +    K  ++L   +G++F  A+GR   ++ ++   LE K+
Sbjct: 1   MIKLIVSDLDGTLLGLDNHVKKEDKLAIQLAVEQGMDFAIASGRMDNEILEVLQELEQKA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM---NRHR 117
           + I+ NGA ++      + A      +A  ++    +   I+  V  ++ +F+   N + 
Sbjct: 61  HRISQNGAFIYTKTNLPLHATTFSPQLAQQIYRQAKELEAIVL-VCNENTYFIEETNENT 119

Query: 118 PE-EMRFFKEAVFQYALYE-PGLLEPEG----VSKVFFTCDSHEQLLPLEQAINARWGDR 171
            E E R F      Y LYE P +L+  G     SK+     ++EQ++  EQ I  ++G+ 
Sbjct: 120 AEIEKRLF------YGLYECPNILDSIGKDIHPSKITVLA-ANEQIVEFEQKITRQFGNH 172

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           ++   S   CL++M   +SKG+A+  + + L     +   FGD  ND  M  +      M
Sbjct: 173 IDTFISEPNCLDIMPKNISKGNAVRTLMEHLRLQPNEIACFGDAFNDTPMFRLTPYSFAM 232

Query: 232 GSAHQRLK 239
             AH  +K
Sbjct: 233 SHAHPNVK 240


>UniRef50_B8CYJ2 Cof-like hydrolase n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYJ2_HALOH
          Length = 267

 Score = 96.3 bits (238), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 80/271 (29%), Positives = 126/271 (46%), Gaps = 15/271 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++VA DLDGTL+  +  LS    + +  L  RG+  V ATGR  +        L IK  
Sbjct: 4   YRMVAMDLDGTLIDENQNLSQVTIDVITELMNRGVICVIATGRMFISALPYVRKLGIKKP 63

Query: 62  MITSNGARVHDLDGNLIFAHN-LDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NGA + D   N +  H  +  ++A  +  +  +  + I N+Y DD   + R   E 
Sbjct: 64  VITYNGAFIKDPVTNKVLHHKPIPLNLAGQVIKITEEYGNHI-NLYEDDRLLVARRNEET 122

Query: 121 MRFFKEAVFQYALYEPGLLEP---EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
           + +  E +      E G L     +  +K+       ++   + + I  +  D + V+ S
Sbjct: 123 LLY--EDIAGVKAREVGPLSDYLGKPPTKLLIIERDRDKYEAIYREIRLQLEDDLAVTRS 180

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               +E+M   +SKG ALE VA      L   IA GD  ND EM+  AG G  MG++ ++
Sbjct: 181 RDIFIEIMGKEISKGKALEKVASGFEIPLSQVIAIGDSWNDLEMIKAAGLGVAMGNSPEQ 240

Query: 238 LK---DLHPELEVIGTNADDAVPHYLRKLYL 265
           +K   DL     V  +N ++ V   L K+ L
Sbjct: 241 IKAEADL-----VTLSNKENGVARILEKVLL 266


>UniRef50_C7RFK7 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7RFK7_ANAPD
          Length = 265

 Score = 95.9 bits (237), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 81/270 (30%), Positives = 126/270 (46%), Gaps = 13/270 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY- 61
           +++  D+DGTL++    ++   +E L      G   V  TGR       + + LE   Y 
Sbjct: 2   KLIGVDVDGTLVNSKRVITERTREALISAMKAGHKVVIVTGRPTAGARNLAEALEFDKYG 61

Query: 62  -MITS-NGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            +I+S NG  + D   G ++  H +D DIA ++  +  D P + T V   D  F  +  P
Sbjct: 62  GLISSFNGGAITDFATGKVLANHEMDHDIAVEMIKLAKDLP-LETMVPYMDTVFSPKIGP 120

Query: 119 ---EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
               E R  +    +    +  +  P  V+K+ F  D      P  + I  R+GD     
Sbjct: 121 YTEGEARTLRMEAKEVEDLDQTIDFP--VNKILFAADPDLIDEPTSK-IKERFGDLTEQV 177

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S     EVM  G+SKG++L  +AK      KD IAFGD MND  M+  AG G  MG+A 
Sbjct: 178 KSARFYYEVMPMGLSKGNSLLEIAKIFNIDQKDIIAFGDEMNDETMIEAAGVGVAMGNAV 237

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            ++K++   + +  TN +D + +YL K  L
Sbjct: 238 SKIKEIADYVTL--TNDEDGIAYYLDKFIL 265


>UniRef50_A6LB32 Haloacid dehalogenase-like hydrolase n=23 Tax=Bacteroidales
           RepID=A6LB32_PARD8
          Length = 268

 Score = 95.5 bits (236), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 70/274 (25%), Positives = 129/274 (47%), Gaps = 21/274 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  DLDGTL +    ++P+ +ETL     +G++ V A+GR    +  + + L IK Y
Sbjct: 3   YKLLVLDLDGTLTNSKKEITPFTRETLLQAQEKGLHLVLASGRPTYGIVPLAEELNIKQY 62

Query: 62  ---MITSNGARVHDL-DGNLIFAHNLDRDIASDLF--------GVVNDNPDIITNVYRDD 109
              +++ NG +V DL    ++F   L  DI   L+         +++ N   I + + ++
Sbjct: 63  GGFILSFNGGKVIDLMTDKVLFEQALPPDIVPVLYNRSKEAGLAILSYNGKYILSEHPEN 122

Query: 110 EWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
           ++        +M+      F   L++P        +         E L+PLE+ +    G
Sbjct: 123 KYVQYESFLTKMKIKATDDFLRDLHQP--------ADKCLVVGEPEMLVPLEEKLRQELG 174

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
            R+NV  S    LE++  G+ K  +L  + ++     ++ IA GDG ND  M+  AG G 
Sbjct: 175 KRINVYRSEAFYLELVPKGIDKAASLSRLLERTRIKQEEVIAIGDGFNDVSMIHFAGLGV 234

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            M +A   +K  + +     TN +D V  ++++L
Sbjct: 235 AMANAQPPVKA-NADRITQYTNDEDGVARFIQEL 267


>UniRef50_A9KKJ5 Cof-like hydrolase n=3 Tax=Clostridiales RepID=A9KKJ5_CLOPH
          Length = 275

 Score = 94.7 bits (234), Expect = 3e-18,   Method: Compositional matrix adjust.
 Identities = 80/281 (28%), Positives = 133/281 (47%), Gaps = 32/281 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY- 61
           +V+A DLDGTL + +  ++   KETL+     G+  V A+GR  V +  +   LE+  Y 
Sbjct: 4   KVLALDLDGTLTNSEKKITLNTKETLQRAMEDGVTVVLASGRPLVGIKPLAKELELSKYS 63

Query: 62  --MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVN---------DNPDIIT----NV 105
             ++  NG ++ D   G  ++   L+ +  + ++ V           D  DIIT    + 
Sbjct: 64  GYILAYNGGQIIDCHTGKEVYQKVLNVERIASIYEVAKQFGVAMLTYDGEDIITEDDTDP 123

Query: 106 YRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN 165
           Y   E F+N+ +   +R  ++ V       P  L              HE+LLP+   + 
Sbjct: 124 YVLRECFINKVK---VRKIEDIVSHVTYPVPKCL----------VVGEHEKLLPVRDYLK 170

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
            ++GD +++ FS    LE+M  GV K  +LE +  +L  S ++ +A GDG+ND  ML  A
Sbjct: 171 DKYGDELSIYFSEPFFLEIMPLGVEKSASLELLLNRLQLSREELMACGDGLNDITMLQYA 230

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           G G  MG+A    K++     +  TN +D V   + +  LS
Sbjct: 231 GLGVAMGNACNEAKEVSK--YITATNDEDGVAKAVNRFILS 269


>UniRef50_A3MZH9 Predicted hydrolases of the HAD superfamily n=9 Tax=Pasteurellaceae
           RepID=A3MZH9_ACTP2
          Length = 272

 Score = 94.4 bits (233), Expect = 4e-18,   Method: Compositional matrix adjust.
 Identities = 79/282 (28%), Positives = 131/282 (46%), Gaps = 35/282 (12%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           YQ +A DLDGTLL+P  T+   +K+ +K    +GI   F TGRHH  V      + + + 
Sbjct: 3   YQAIAFDLDGTLLNPHATILESSKQAIKKAREKGIKVFFVTGRHHTAVRPYYAEIGLDTP 62

Query: 62  MITSNGARVHDLDGNLIFAHN-LDRDIASDLFGVVND--NPDIITNVYRDDEWFMNRHRP 118
           ++  NG  ++D   + + +   L  + AS L   +ND  +  I T VY  D     +  P
Sbjct: 63  VVCCNGTYLYDFQHDKVLSGKPLTAEQASHL---INDAKSQGIHTAVYFRDAMTYEQLNP 119

Query: 119 EEMRF----------FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQL------LPLEQ 162
              +            +  V+Q   ++  + +   V KV  +  + E++      LPL+Q
Sbjct: 120 HFAKLQQWVASCPESVRPNVYQLESFQQEIDKGTTVWKVLISDPNLEKMQNFVKKLPLDQ 179

Query: 163 -AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEM 221
            +    W DRV+++          + G SKG  L  + K  G   ++ IAFGD  ND  M
Sbjct: 180 FSPEWSWVDRVDIT----------SVGNSKGAMLAELLKMEGLEPQNVIAFGDNFNDISM 229

Query: 222 LSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           L + G G  MG + + +K      + IG+N++D++   L +L
Sbjct: 230 LELVGLGIAMGDSEEEVKQRAD--KTIGSNSEDSIAKTLTEL 269


>UniRef50_B0ADP8 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0ADP8_9CLOT
          Length = 273

 Score = 94.0 bits (232), Expect = 5e-18,   Method: Compositional matrix adjust.
 Identities = 75/286 (26%), Positives = 135/286 (47%), Gaps = 42/286 (14%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ SD+DGTLL  +H ++   K  L     +G+  V A+GR +    +  D L+I + 
Sbjct: 3   YKLIVSDMDGTLLGDNHKITEENKIALSKALEKGVKIVPASGRIYNSAREHFDFLDINTP 62

Query: 62  MITSNGARVHDLDGN-LIFAHNLDRDIASDL----------FGVVNDNPDIITNVYRDDE 110
           +I  NGA + +   N LI+ +N+  DI   +          + + ++N  +  N+ ++D+
Sbjct: 63  LIACNGAIIKETKTNKLIYKNNIPNDICLKIIDIFEKNEVYYQLYSENTMMCKNLSKEDQ 122

Query: 111 WFMNRHRPEEMRFF-------------KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQL 157
               R   E ++ F             KE V ++ + +   ++   + K+    +  +Q+
Sbjct: 123 ----RQTKERLKNFFNDDINVHFGDDLKEEVIKHKILKIIAIDDYDMDKLKKVKEDLDQI 178

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
             +E  I + W + V          E+M  GV+KG AL+A+   LG    + IAFGD  N
Sbjct: 179 EDIE--ITSSWFNNV----------EIMHKGVNKGEALKALINYLGIDKDEVIAFGDNYN 226

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           D  ML +AG G +MG+A+  +K+      +   N +D V   + K 
Sbjct: 227 DLPMLELAGIGVVMGNANDEVKEKGD--YITAKNTEDGVAKAIYKF 270


>UniRef50_Q0B097 Putative uncharacterized protein n=1 Tax=Syntrophomonas wolfei
           subsp. wolfei str. Goettingen RepID=Q0B097_SYNWW
          Length = 268

 Score = 93.2 bits (230), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 71/267 (26%), Positives = 124/267 (46%), Gaps = 8/267 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VA DLD TLL     +     E +  +  +G+    ATGR           L++   +
Sbjct: 4   ELVAIDLDDTLLDSTWKIPESCLEAISQVQRKGVRVTLATGRMFRSALPYAQQLKVDIPL 63

Query: 63  ITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           IT  GA V +     +++   L R +A+++     +   I    Y +D + + R  PE  
Sbjct: 64  ITYQGALVKNSFSQEVLYYEPLPRKLAAEIMIFFKER-GIFYQSYFNDCFCIERWSPE-A 121

Query: 122 RFFKEAVFQYALYEPGLL---EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           +++ E      L+   L+     +   K+  +      +L +E+ +N R+G+ + ++ S 
Sbjct: 122 QYYAELSGMEPLFYDDLIAVSREQDTPKILASIFDERLMLAIEEELNRRYGEELYITRSK 181

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LEVM   V KG AL+ +A+  G   +  +AFGD  ND  M+  AG G  MG+A + +
Sbjct: 182 PVFLEVMKRSVDKGLALKMLARYFGIPREKVLAFGDSYNDLAMIKWAGIGVAMGNAPEVV 241

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K+    L    +N ++ V H L +L L
Sbjct: 242 KEAADYLA--PSNEEEGVAHVLHELIL 266


>UniRef50_C9KQH1 HAD phosphatase family protein n=2 Tax=Clostridia
           RepID=C9KQH1_9FIRM
          Length = 274

 Score = 93.2 bits (230), Expect = 7e-18,   Method: Compositional matrix adjust.
 Identities = 74/279 (26%), Positives = 127/279 (45%), Gaps = 24/279 (8%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A DLDGTL + +  ++   +E L  +   G+  V A+GR    + +    L++K 
Sbjct: 1   MYKMIALDLDGTLNNDEKKITEKTREALLSVQQHGVTVVLASGRQAPGLAREAQALDLKD 60

Query: 61  Y---MITSNGARVHD-LDGNLIFAHNLDRDIA----------SDLFGVVNDNPDIITNVY 106
           Y   +++ NG R+ D   G ++F   +DR  A           +L  +V+D   I T   
Sbjct: 61  YHGLLLSYNGGRIQDATTGEVLFDQAIDRATALRFLRHLEAYPELSPIVDDGESIFTTDA 120

Query: 107 RDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKV-FFTCDSHEQLLPLEQAIN 165
           R       RH+ ++         +        +E  G + V   T   +E L+P  + I 
Sbjct: 121 R-------RHKVQDESRNNNLKVEIVANIADAVEARGFAPVKILTAAPNEILVPRLEDIR 173

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
             + D ++   S     E    GVSK  +L  V ++ G +  + +AFGD  ND  ML  A
Sbjct: 174 RGFEDELSFVQSAPWFYEATVKGVSKSTSLAIVCERFGIARAEVMAFGDAQNDMSMLDFA 233

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G G  MG+A   LK++  E+ +  +N +D +   L + +
Sbjct: 234 GHGVAMGNACPELKEMADEITL--SNNEDGIAASLTRHF 270


>UniRef50_A6TLP5 Cof-like hydrolase n=2 Tax=Firmicutes RepID=A6TLP5_ALKMQ
          Length = 259

 Score = 93.2 bits (230), Expect = 8e-18,   Method: Compositional matrix adjust.
 Identities = 71/242 (29%), Positives = 113/242 (46%), Gaps = 18/242 (7%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V  D+DGTLL  D  +    K+ +K L  +G+    ATGR       IR+ L I +Y 
Sbjct: 6   KIVFFDIDGTLLDHDKKMPDSTKKAIKDLKDKGVYVAIATGRAPFHFEDIREELGIDTY- 64

Query: 63  ITSNGARVHDLDGNLIFAHNLDRD--IASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++ NG  V  L+G +I+   L  +   A +   + + +P I  N ++D +  +  H P  
Sbjct: 65  VSCNGGYVV-LEGKVIYKSILPTEDLRAIENLAMKSQHPIIYLN-HQDFKVNIEGH-PAV 121

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPL---EQAINARWGDRVNVSFS 177
            +   +      LY+P  +    +      C   E+ + +   E  +  RW ++      
Sbjct: 122 EKCMADLKLSEPLYDPNFMSQNEIYHAILCCQKEEEAIYMNRSEDFVFLRWHEQ------ 175

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               L+++  G+SK   +EA+ K L Y  KD  AFGDG ND EML   G G  MG+A   
Sbjct: 176 ---ALDIIPKGLSKAKGIEAILKALSYERKDSYAFGDGHNDMEMLEFVGTGIAMGNALAE 232

Query: 238 LK 239
           LK
Sbjct: 233 LK 234


>UniRef50_B0K375 Cof-like hydrolase n=11 Tax=Thermoanaerobacterales
           RepID=B0K375_THEPX
          Length = 273

 Score = 93.2 bits (230), Expect = 9e-18,   Method: Compositional matrix adjust.
 Identities = 76/273 (27%), Positives = 129/273 (47%), Gaps = 13/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++  +D DG+LL+ +  +S   KE +K + +RG+ F  ATGR    +      L I +
Sbjct: 1   MYKLFVTDADGSLLNSNSEISDKNKEAIKEVISRGVIFTIATGRMFSSILPYALELNINA 60

Query: 61  YMITSNGARVHDLDGNLIFAHN----LDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR- 115
            +I+ NGA + D+    ++ +N     D   A  L   +  +     N+Y DDE ++   
Sbjct: 61  PVISYNGALIKDIYTKKVYYYNPIQTEDAIFAIRLLKEIGYH----INLYIDDELYVEEI 116

Query: 116 -HRPE-EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
             R E  + F    V      E  L    GV+   +  +  +  + ++  I      R+ 
Sbjct: 117 TDRVEWYLSFNNVTVNAVGNLEEFLKRTGGVTAKIYAINDMKNPISIDAEIYDEISKRLT 176

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +S S    LE+ A GVSKG+AL+ +A       +  +A GD +ND  M+  AG G  MG+
Sbjct: 177 ISTSGGGHLEINAKGVSKGNALKTLANMYSIKREQVVAIGDNLNDLSMIEYAGLGVAMGN 236

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A   +K +  +   + +N +D V H + K +L+
Sbjct: 237 APDIVK-IKADYTTL-SNDEDGVAHAIDKFFLN 267


>UniRef50_Q2RLU7 HAD-superfamily hydrolase subfamily IIB n=1 Tax=Moorella
           thermoacetica ATCC 39073 RepID=Q2RLU7_MOOTA
          Length = 272

 Score = 92.8 bits (229), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 81/281 (28%), Positives = 126/281 (44%), Gaps = 35/281 (12%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VA DLDGTLL+ D  + P A+E ++ +  +GI    ATGR           L ++  +
Sbjct: 5   RLVALDLDGTLLTDDIVIEPRAREAIRKVKEKGITVTLATGRMFSSARPYAVELGLELPL 64

Query: 63  ITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR------ 115
           I  +GA+V H   G ++F   L   +A  L   + +      NVY DD  ++        
Sbjct: 65  IVYHGAQVRHSTTGEILFERTLPVPLALRLIKNIKEF-GYPYNVYLDDRLYVESIQAENE 123

Query: 116 ----------HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN 165
                     HR E+M  F E             +P+G  K+    D    L PLE AI 
Sbjct: 124 EYAWRAGVDLHRVEDMLTFLEQ------------QPKGPLKIVALHDG-PALDPLEAAIR 170

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
              G  + ++ S  T LE++   V+K   L+A+A+  G S ++ +  GD  ND +M   A
Sbjct: 171 REAGAGIYITRSMPTYLELLNPEVNKARGLQALAELEGISPEEIMVCGDSYNDVQMFRYA 230

Query: 226 GKGCIMGSAHQRLKDLHPELE-VIGTNADDAVPHYLRKLYL 265
           G    M +A ++++    E + V G+N D  V   L K  L
Sbjct: 231 GLAVAMANAPEKVR---AEADYVTGSNNDGGVAQALEKFVL 268


>UniRef50_B0K874 Cof-like hydrolase n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K874_THEP3
          Length = 274

 Score = 92.4 bits (228), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 76/278 (27%), Positives = 130/278 (46%), Gaps = 22/278 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+D TLL  D T+S    E L     +G+  V +TGR         D +  ++Y
Sbjct: 3   YKLIAIDMDDTLLRHDKTISKENIEALHKAREKGVYVVISTGRVFASAYAYADMIGFRTY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDL----------FGVVND----NPDIITNVYR 107
           +I SNGA + D D N I+   L+ D   ++          F +++D    +P+I     R
Sbjct: 63  IIASNGALIRDPDNNTIYESLLNYDSMEEIIKVCQKYNTYFQLISDKTVFSPEITNKFQR 122

Query: 108 DDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
             EW  N     E++   + V +  L E   L+   + K+    D  E L  + + ++  
Sbjct: 123 YAEW--NELFKTELKVDVQEV-KEPLKELDKLKS-SILKIIVFNDDVEVLKSIREELSKN 178

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
               + ++ S +  +E++  GVSKG AL+ +   LG   ++ IA GD  ND EM+  AG 
Sbjct: 179 TS--IQITSSYMDNIEIVNKGVSKGRALKILGGYLGIEREEMIAIGDSENDIEMIKFAGL 236

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G  + +A   +K +     +  +N +D V + + K  L
Sbjct: 237 GVAVENAIDEVKKVAD--FITKSNMEDGVKYVIDKFIL 272


>UniRef50_C6PMT7 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PMT7_9CLOT
          Length = 267

 Score = 92.4 bits (228), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 72/284 (25%), Positives = 131/284 (46%), Gaps = 36/284 (12%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           MY+++A D+DGTLL+ +  +S   KE ++    +G+N V  +GR    V    D + ++ 
Sbjct: 1   MYKLLAVDMDGTLLNSNRIISKANKEAIRKAVEKGVNVVITSGRGLKGVDNFLDEVHLRG 60

Query: 60  --SYMITSNGARVHDLDG------------NLIFAHNLDRDIASDLFGVVNDNPDIITNV 105
              Y+I +NG  ++                +LI AH L +    ++    ++ P      
Sbjct: 61  ENQYLIANNGGTIYRTSNFECVAYKGLRGRDLIKAHTLSKKFGLNMIAYTHEGP------ 114

Query: 106 YRDDEWFMNRHRPEEMRFFKEAV---FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQ 162
                  +     E  RF  E V    +   ++  + + + ++K+ F+    E+LL  + 
Sbjct: 115 -------IAAEESEFTRFEAEYVGTPVKIINFKSDIEDNDEITKILFS--QTEELLDKKM 165

Query: 163 -AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEM 221
             +  ++    NV  +    LEVM    +KG+ ++ +A KLG   ++ +  GD  ND EM
Sbjct: 166 LELPKKFYTEYNVVKTMPIILEVMNKNCNKGYGVKVLADKLGIKKEEVMCIGDQANDVEM 225

Query: 222 LSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           L+ AG G  MG+A + LKD+   + +   N +D V   ++K  L
Sbjct: 226 LTYAGLGVAMGNAIEELKDIAQYVTL--DNDNDGVAKAIKKFIL 267


>UniRef50_C6JLL1 Hydrolase n=2 Tax=Fusobacterium RepID=C6JLL1_FUSVA
          Length = 265

 Score = 92.4 bits (228), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 75/270 (27%), Positives = 131/270 (48%), Gaps = 21/270 (7%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLL+ D  +S + ++ L   +  GI  V A+GR    +  +   L +K Y 
Sbjct: 8   KLIAMDLDGTLLTKDKRVSDFNRDILNKKSNEGIELVIASGRDLYSIMDLTGCLNVK-YH 66

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLF-GVVNDNPDIITNVYR-------DDEWFMN 114
           I  NGA+++  +  LI++ +++++I  D+    V    D      R       D E+   
Sbjct: 67  ICFNGAKIYK-NKKLIYSKSMNKEICLDILEKAVEIGLDYSATAGREVHFTKIDPEYVKE 125

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
               +E+RFF           P   E E   K+ F  D+ ++   L + +  ++G+ +N+
Sbjct: 126 YKANKELRFF-----HITDRRPLGREFE---KMVFVGDA-DKFKKLRKYVTEKYGNELNI 176

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    ++++    SKG AL+ VA+ +G  +   +AFGD  ND  ML +AG   IM +A
Sbjct: 177 FGSGDGVMDIVNIQCSKGEALKNVAEDIGIPIGQTMAFGDNENDLSMLDIAGCSVIMANA 236

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            + LK    E  V  TN ++ V  ++   +
Sbjct: 237 AEELKKSKYERTV--TNDENGVGTFVENFF 264


>UniRef50_C9XMM6 Putative hydrolase n=4 Tax=Clostridium difficile RepID=C9XMM6_CLODC
          Length = 284

 Score = 92.4 bits (228), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 75/278 (26%), Positives = 131/278 (47%), Gaps = 21/278 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ +D+DGTLL  +H ++   K  L+ +   GIN   ATGR         D L+    
Sbjct: 3   YKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATGRAFDSAKCNVDFLKEDMP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I  NG+ + + +GN+I+++ +D     ++  V+ D  DI       D     ++R   +
Sbjct: 63  IIACNGSLIREQNGNIIYSNKIDTRTCLNILDVL-DKYDIYYQCNSIDSMLYEKNRRTIL 121

Query: 122 RFFKE--------AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINA------- 166
            F K+        +VF  +  E  ++  + + +  F  D  + ++  E+  +        
Sbjct: 122 CFTKKIEGREDRLSVFLGS--ETEVIVKDDLREEIFKKDILKFVIIEEKNPSILDEIRKE 179

Query: 167 -RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
            R    + ++ S    +EVM  GV KG+A++ +A+K+    +D IAFGD  ND EM+  A
Sbjct: 180 LRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDNYNDIEMIKFA 239

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           G G  MG+A + +K       V  TN D  V   + K 
Sbjct: 240 GLGVAMGNAEELIK--QEADYVTDTNQDSGVAKAIYKF 275


>UniRef50_Q97ES2 HAD superfamily hydrolase n=1 Tax=Clostridium acetobutylicum
           RepID=Q97ES2_CLOAB
          Length = 280

 Score = 92.0 bits (227), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 73/282 (25%), Positives = 129/282 (45%), Gaps = 26/282 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V  D+DGTLL+  H +S   KE ++   A+G++ V  TGR + +       + +KS 
Sbjct: 3   YKLVCIDMDGTLLNSKHCVSGETKEVIRKAYAKGVDIVITTGRIYANAAFYSKLIGVKSP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDD-----------E 110
           +I SNGA +   D N+I+ + L  D  S +F V +     IT    D             
Sbjct: 63  VIASNGAIIRGRDNNIIYKNVLSSDTLSRIFNVCSRLKGNITLHTHDSIICSSKFAYIVM 122

Query: 111 WFM-------NRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQA 163
           W +       N     ++++ K     Y+ Y  GL E   + K        +++  + + 
Sbjct: 123 WVIFIGSIIKNNENTLKIKYVK----NYSAYINGLKESNDIIKCEIIDKDVKKISAIREE 178

Query: 164 INARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLS 223
           +  R  D + V  S+   +EV +  VSKG+A++++A+  G   ++ I  GD  ND  M+ 
Sbjct: 179 L-KRMND-IEVVSSSRHNIEVTSKNVSKGNAIKSLAEFYGIKREEIITIGDSENDLSMIE 236

Query: 224 MAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             G G +M +  +  K L     +  TN ++ V   ++K  +
Sbjct: 237 YGGLGVVMENGCESAKKLAD--YITDTNDNNGVAKVIKKFIM 276


>UniRef50_C4L3P2 Cof-like hydrolase n=2 Tax=Exiguobacterium RepID=C4L3P2_EXISA
          Length = 295

 Score = 92.0 bits (227), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 79/270 (29%), Positives = 125/270 (46%), Gaps = 40/270 (14%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++  SD+DGT+L     ++    E ++   A GI F  ATGR++V+  QI D + +   
Sbjct: 4   YKLFVSDMDGTILHNHTKIADETAEIVREAEAAGIRFAIATGRNYVNAKQILDEVGLSCP 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIA-------------SDLF-------GVVNDNPDI 101
           +++SNG RV D  G ++   +L  D A             +D+F       G+V    D+
Sbjct: 64  IVSSNGGRVLDTSGEVLHEIDLTIDEALQVINVLHQDDKYADVFYEMYTEAGLVASRGDL 123

Query: 102 ITNVYR------DD------EWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFF 149
           I    +      DD      E+F NR+      +  E V      E  + E  G    F 
Sbjct: 124 IEASMKNLKANGDDRSLEMYEFFKNRY------YVNEDVKIVDDIEGFIREEAGRVYKFI 177

Query: 150 TCDSH-EQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKD 208
              SH E++  L + I  +  + V V+ S    +EVMA G  KG+ +  +A+  G  L +
Sbjct: 178 AFSSHLEKMNGLWKEIEDQV-EGVYVTSSGNDNIEVMAHGADKGNGVTKLAEHYGIDLSE 236

Query: 209 CIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
            +  GD +ND  M  +AGKG  MG++H+ L
Sbjct: 237 VVVIGDNLNDVPMFKVAGKGIAMGNSHEDL 266


>UniRef50_Q8ENE7 Hypothetical conserved protein n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8ENE7_OCEIH
          Length = 246

 Score = 91.7 bits (226), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 71/268 (26%), Positives = 131/268 (48%), Gaps = 34/268 (12%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGTLL+P+H +S   K+ ++    +GI+ + +TGR         + L + SY+
Sbjct: 8   KLIALDMDGTLLTPEHEVSERNKKAIQTALEQGIDVILSTGRSWDTCFPFAEELSLTSYL 67

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           IT+NG ++  ++  L+  H L  +    ++ +  +      N++    W ++        
Sbjct: 68  ITANGGQIWTVEKELLQQHLLKTETVEKMYLLAKEK-----NMHC---WMIST------- 112

Query: 123 FFKEAVFQY----ALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINA-RWGDRVNVSFS 177
              E VF+      LY+   L+        F C S ++   L+Q I    + D + ++ S
Sbjct: 113 ---EKVFRGHAPDNLYDHQWLK--------FGCASEDK-NKLDQMIKELSYNDELELTNS 160

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
             T +E+   GVSK  AL+ + +K+G ++ + +A GD +ND +M+  AG G  MG+A   
Sbjct: 161 LPTNIEINPKGVSKAQALQFLCEKIGITMDNVMAVGDSLNDIKMIQEAGVGVAMGNAQVA 220

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +K +        TN +D V   + K  L
Sbjct: 221 IKKVAN--YTTDTNEEDGVGIAIEKYAL 246


>UniRef50_C7NEL2 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7NEL2_LEPBD
          Length = 263

 Score = 91.7 bits (226), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 69/262 (26%), Positives = 124/262 (47%), Gaps = 4/262 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           + +  DLDGT+L+ +H +S    + L+ L  +G+    ATGR  +      + LEIK+ +
Sbjct: 5   KAIFMDLDGTVLTSEHKVSENLIKKLRELEEKGVKTFIATGRTFISSKPFVEMLEIKNPV 64

Query: 63  ITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           I  NG RV + L+  +IF   ++     +L  V  +   I  N+Y DD+ ++     E  
Sbjct: 65  INYNGGRVTNPLNNEVIFEKPVEAQDVKELIKVSREK-GIHLNLYMDDKLYIENETDEGK 123

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           ++ +     Y +        +  +K  F  ++   +L   +         +N  FS    
Sbjct: 124 KYSESVEIPYYVKNFDEFIGKTSTKALFITEN--SILLELKKELEEKLPHINFVFSKPHY 181

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE +   V+KG A++ + KK   S ++ +AFGD  ND EML     G +MG+A + LK  
Sbjct: 182 LECLNKEVNKGLAIKELLKKYDISPEETMAFGDQWNDLEMLKFVKYGYLMGNATEELKQE 241

Query: 242 HPELEVIGTNADDAVPHYLRKL 263
             + ++  +N +D +   ++ L
Sbjct: 242 FSKDKITLSNDEDGIYEVIKAL 263


>UniRef50_B1L8F5 Cof-like hydrolase n=6 Tax=Thermotogaceae RepID=B1L8F5_THESQ
          Length = 268

 Score = 91.7 bits (226), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 75/267 (28%), Positives = 132/267 (49%), Gaps = 10/267 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+V   DLDGTLL+    +S   ++ ++ L+ R  + VFA+GR  V    +      ++
Sbjct: 1   MYRVFVFDLDGTLLNDSLEISEKDRKVIERLS-RNCHVVFASGRMLVSTLNVEKKYFGRT 59

Query: 61  Y-MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
           +  I  NGA V+  +  +I    +  ++A D+   V    ++    Y DD  +  +   E
Sbjct: 60  FPTIAYNGAMVYIPEEGVILNEKIPPEVAKDIVEYVK-QFNVHWQAYIDDVLYSEKDNEE 118

Query: 120 EMRFFKEAVFQYALYEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
              + K +  +Y + EP LLE     G +K+    D+ E+L  L++ +  ++ + V V  
Sbjct: 119 IRGYAKHSSVEYRV-EPKLLELVSKVGTTKILL-IDTPEKLDELKKILLEKFNNVVKVFK 176

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S  T LE++   V KG AL  + +++G+  ++ + FGD  ND  M   AG    MG+A  
Sbjct: 177 SFPTYLEIVPENVDKGKALRFLRERMGWKKEEIVVFGDNENDLFMFEEAGLRVAMGNAID 236

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKL 263
           ++K+    + +  TN D  V H L ++
Sbjct: 237 KVKEAADVVTL--TNNDSGVSHVLERI 261


>UniRef50_C0Z8L2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z8L2_BREBN
          Length = 279

 Score = 91.3 bits (225), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 73/289 (25%), Positives = 127/289 (43%), Gaps = 37/289 (12%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+DGT+L  +HTLS   +  +  L  +G++   ATGR +     +     I + 
Sbjct: 3   YKLLALDVDGTILMSNHTLSKVTERAITQLVQQGVHVTLATGRAYPSAKSLAQQFRISAP 62

Query: 62  MITSNGARVHDLDGN------------------LIFAHNLDRDIASDLFGVVNDNPDI-- 101
           +++ +GA V D   +                  ++ +H LD  +  + + V N    +  
Sbjct: 63  LVSHDGAYVADPKTDQVLYVQRIPHEIAARITDILVSHGLDVMLLHEAYAVTNRTWKLTD 122

Query: 102 ---ITNVYRDDEWFMNRH--RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQ 156
              + N +   + + N++  + +  R     V ++ +  P         K+F T D  ++
Sbjct: 123 LFPLLNAWTLRQLWKNQYPLKIQASRLIAGYVRKHEVCAP---------KIFVTGD-EKR 172

Query: 157 LLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGM 216
           LL   Q +       + V+ S    LE++  G+SK   L  V+++L     + +A GD  
Sbjct: 173 LLEARQELEKAELSGIRVTASGANNLEILPVGISKASGLAVVSERLAIQPDEIVAVGDNY 232

Query: 217 NDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           NDAEML  AG G  MG+A   LK L     V  TN    V   + K +L
Sbjct: 233 NDAEMLQFAGMGVAMGNAPDDLKQL--ARHVTETNDRHGVAEVIEKFFL 279


>UniRef50_C3WG77 HAD hydrolase n=1 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WG77_FUSMR
          Length = 268

 Score = 91.3 bits (225), Expect = 3e-17,   Method: Compositional matrix adjust.
 Identities = 74/269 (27%), Positives = 126/269 (46%), Gaps = 25/269 (9%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETL-KLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           +++ +DLDGTLLS +  +S Y  E L + +  + I  V A+GR    +  +  +L+IK Y
Sbjct: 7   KLIVTDLDGTLLSDEKKVSEYNIEILNRAVKEKEIELVVASGRDIYSIKNLTKDLKIK-Y 65

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDL----------FGVVNDNPDIITNVYRDDEW 111
            I  NGA++++ D  LI+   +D  I  D+          F   ++N    T +  D+E+
Sbjct: 66  YICFNGAKIYN-DDKLIYKEAIDEKICEDILKKGMELNLKFSATSENEIHYTKM--DNEY 122

Query: 112 FMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
               +  ++++ F        L     ++     K+ F     E L  L   +  ++G++
Sbjct: 123 TRLENGKDKLKSF-------YLKSKEDIKQRNFEKIVFVGLEVE-LTQLRNYVEKKYGNK 174

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           VN  +S    L+++    SKG A+E +A  L       IAFGD  ND  ML + G   IM
Sbjct: 175 VNTFYSGSGVLDIVNKKCSKGTAVEEIATLLNIDKSKIIAFGDNENDISMLELVGHPVIM 234

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYL 260
            ++ + LK       V  +N +D V  Y+
Sbjct: 235 ENSREDLKKKKYYKTV--SNNNDGVGKYI 261


>UniRef50_A0AEX0 Complete genome n=17 Tax=Listeria RepID=A0AEX0_LISW6
          Length = 270

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 73/273 (26%), Positives = 131/273 (47%), Gaps = 11/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIR---DNLE 57
           MY+++A D+DGTLL+  H ++P  ++++K    +G+  V  TGR    + +     D LE
Sbjct: 1   MYKIIAIDIDGTLLNDAHKITPAVRDSIKAAKEKGVKVVLCTGRPLAGIKKSLIELDLLE 60

Query: 58  IKSYMITSNGARVHDLDGNLIFAH-NLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NGA V +       A   L++    +++   +   ++    +     ++   
Sbjct: 61  AGDYAITFNGAVVLETASEKTLADITLNKAELEEIYAFCHAE-NVNVTYFDGKNMYVPSR 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLE-PEG--VSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
           +  E+      + Q  LY   + E P+   VSK+    DS E++  + + +     ++  
Sbjct: 120 KITEITCQDSLLLQTPLYHLPVEEAPDSIHVSKIML-LDSPEKITDVIKKLPDTIKEKFY 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V  S    LE +  GV+KG AL ++A KLG    + ++ GD  ND  M+  AG G  MG+
Sbjct: 179 VVRSVPYNLEFLQKGVNKGSALASLASKLGVKQSEVMSIGDQENDTTMIEYAGMGVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A + +K++        TN +D V + ++ L L+
Sbjct: 239 ATEHIKEIAN--YTTTTNNEDGVANAIQMLVLN 269


>UniRef50_C8WUD0 Cof-like hydrolase n=2 Tax=Alicyclobacillus acidocaldarius
           RepID=C8WUD0_ALIAD
          Length = 265

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 67/236 (28%), Positives = 110/236 (46%), Gaps = 14/236 (5%)

Query: 8   DLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNG 67
           D+DGTL+     LSP  +E L  L  RG+    ATGR    +  I + L   SY+  + G
Sbjct: 9   DIDGTLIDDRRELSPRVEEALAALRRRGVETAIATGRAPDQLRPIAERLGFDSYVCCNGG 68

Query: 68  ARVHDLDGNLIFAHNLDRDIASDLFGVVNDN--PDIITNVYRDDEWFMNRHRPEEMR--F 123
             V+   G+ + A ++ RD+ +    +   N  P ++     D+  + NR    E+R  +
Sbjct: 69  LAVYR--GDKVLAASVPRDVIASFVELAESNGYPVVVAG---DEACYANRRDHAEIREAY 123

Query: 124 FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLE 183
               +    +Y+P   + E V +++  C   ++  P  +A    + D +         L+
Sbjct: 124 RFLGLPSEPVYDPDAWKREDVYQLYLFCKPGQEA-PFVEA----YRDALRFIRPHRFYLD 178

Query: 184 VMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           V   GVSK   +EA+ +  G S ++ +AFGD  ND EML   G G  MG+A +  K
Sbjct: 179 VFPAGVSKATGVEAILRSAGCSKEEAVAFGDSENDVEMLKYVGMGVAMGNAAEPAK 234


>UniRef50_C5NXD6 Phosphatase YidA n=1 Tax=Gemella haemolysans ATCC 10379
           RepID=C5NXD6_9BACL
          Length = 270

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 76/283 (26%), Positives = 136/283 (48%), Gaps = 35/283 (12%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++V +D+D TLL+ D  +S   +E ++    + I  + A+GR    +  I ++L++ S
Sbjct: 1   MIKLVVTDIDDTLLNSDREISKKNREVIEECKKQDIKVILASGRPDFGMMSIVEDLQLDS 60

Query: 61  Y---MITSNGARVHDLDGN-LIFAHNLDRDIASDLFGV-VNDNPDIITNVYRDDEWFMNR 115
           Y   +++ NGAR+ +L  N +I+   L  +    L  V + +N DI+T  Y+  +   NR
Sbjct: 61  YDNYLLSFNGARIANLKTNEVIYEKFLSPERIKFLIDVALENNCDILT--YQGGKVLTNR 118

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLE-------------PEGVSKVFFTCDSHEQLLPLEQ 162
                         +YA  E GL+               EG +KV       E +  ++ 
Sbjct: 119 DN------------EYARIESGLVSAELVISENMKDDIKEGAAKVIILKHPDEAV-AVKD 165

Query: 163 AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
            +    GD   V+ S    +E+   G+SKG +L+++ KKLG + ++ +A GDG+ND  M+
Sbjct: 166 KLALELGDEYEVAMSKPFFIELNDKGISKGVSLDSLCKKLGLTNENVMALGDGLNDLSMI 225

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             AG G  + +A+  LK+    +    +N +D   + + K  L
Sbjct: 226 EFAGMGVAVDNANPTLKEAANFIS--KSNDEDGFAYAIEKFVL 266


>UniRef50_C2EBE1 HAD superfamily hydrolase n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2EBE1_9LACO
          Length = 288

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 61/251 (24%), Positives = 126/251 (50%), Gaps = 13/251 (5%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           MY+++  D+D TLL+ + T++P   E +K    +G+ F   TGR  + V    + L +K 
Sbjct: 18  MYKLIVCDMDETLLADNKTITPKTVEAIKRAVKKGVRFSPNTGRGFLSVQDDLEKLGLKD 77

Query: 60  ---SYMITSNGAR-VHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I++NGA  V + +  ++    +  +  ++LF +  ++P+   ++Y  DE ++  
Sbjct: 78  VSGQYVISNNGAVIVENKNNRIVKTETMKFETVNELFKLGIEHPEYCVHIYTPDELYIWN 137

Query: 116 HRPEEMRFFKEAVFQYALYEPG-----LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
              EE  +    +  Y   +P       L+ + ++K+ F+  S  + L L++ +   + +
Sbjct: 138 LTDEEFAYIDGRLNDYE--QPKDESIEFLKEKQITKIIFSVPSEGERLALQKYVQENF-E 194

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            +N++FS+   +E  +    KG A   + + LG   ++ IA GD  ND  M+  AG G  
Sbjct: 195 EMNITFSSDRYIEFNSKEADKGQAALHLGELLGIKPEEIIAIGDNGNDVPMIKAAGLGVS 254

Query: 231 MGSAHQRLKDL 241
           + +  + +K++
Sbjct: 255 VANGREFVKEI 265


>UniRef50_C5NX92 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Gemella
           haemolysans ATCC 10379 RepID=C5NX92_9BACL
          Length = 277

 Score = 90.9 bits (224), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 70/273 (25%), Positives = 129/273 (47%), Gaps = 20/273 (7%)

Query: 7   SDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSN 66
           +D+DGT L+    ++P AK+ +  L  +G  F+ ATGR  + V     NL +   +I++N
Sbjct: 6   TDMDGTFLNDKKEVAPNAKDVIVKLQDKGSKFIIATGRPDIAVKHYYYNLGMNDVVISNN 65

Query: 67  GARVHDLD-GNLIFAHNL---DRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           G+ + +L  G +++  +    + +   ++F  +ND+ +I  +VY  +  + N       R
Sbjct: 66  GSLIRNLSTGEIVYQKSFKIEEIEKIYNMFKELNDD-EIEFHVYTLNYIYCNHLSFSMAR 124

Query: 123 FFK-EAVFQYALYEPGLL----------EPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
             K EA     L  P  +            E   K+      H++++     ++      
Sbjct: 125 MKKLEADMPEELKTPMYIHDDIIGEIKKNKEDCQKIMMIAKDHDKVVNFFNEVSRVL--E 182

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           V+ +FS     ++M  G +KG A+E +A+     ++DC+ FGD  ND EM  +AG     
Sbjct: 183 VDGTFSATDFFDIMPKGCNKGTAIEKLAEYYNSPIEDCVVFGDNFNDKEMFDVAGWSVCP 242

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +A + ++++    EVIG N D +V  Y+   Y
Sbjct: 243 SNAKEEIQNMCD--EVIGNNNDFSVIKYVEDYY 273


>UniRef50_B7HYF7 Hydrolase, haloacid dehalogenase-like family n=81 Tax=Bacillales
           RepID=B7HYF7_BACC7
          Length = 273

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 80/277 (28%), Positives = 133/277 (48%), Gaps = 23/277 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++  DLD TLL  DHT+SP  KE L     +G+  V A+GR    +  +   L ++  
Sbjct: 3   YKMIVLDLDDTLLRDDHTISPRTKEALMTAQEQGVKVVLASGRPTFGMRNVAKELRLEEY 62

Query: 60  -SYMITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
            S++++ NGA++ +   N  IF+  L  +I  +LF + +   D+  + Y  D+     + 
Sbjct: 63  GSFILSFNGAKIINCKTNEEIFSSTLSPEIVHNLFEI-SKTEDVWIHTYMGDDIVTEENN 121

Query: 118 PEE--------MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
           P          M       F+ A+ EP       V KV    ++ E+L+ +E+ +  +  
Sbjct: 122 PYTEIEGDITGMPIVVVDDFKAAVKEP-------VVKVLMNKEA-ERLVEVEKKLQKQLE 173

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
            +++V  S    LE    GV+KG +L  + +KLG   ++ IA GD  ND  M+  AG G 
Sbjct: 174 GQLSVMRSKPFFLEFTEAGVTKGTSLNQLIQKLGIKREEVIAMGDSYNDQAMIEFAGLGV 233

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            MG+A   +K++     V  TN +D V   + K  L 
Sbjct: 234 AMGNAPDDIKEIAN--YVTDTNMNDGVAKVVEKFVLK 268


>UniRef50_Q03M97 Predicted hydrolase of the HAD superfamily n=68 Tax=Bacilli
           RepID=Q03M97_STRTD
          Length = 270

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 78/271 (28%), Positives = 128/271 (47%), Gaps = 12/271 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  DLDGTLL PD T+S + ++T+K +  +G   V ATGR +         L +++ +
Sbjct: 4   KLIVLDLDGTLLRPDGTISEFTQKTIKDVQNKGHQVVIATGRPYRMAIDHYKTLGLETPL 63

Query: 63  ITSNGARVHDLDGNLIFAHN--LDRDIASDLFGVVND-NPDIITNVYRDDEWFMNRHRPE 119
           IT NG+  +  D N  + H+  LD+    +L    ++   D + + YR   ++++ + PE
Sbjct: 64  ITFNGSLTNLPDQNWAYEHSVKLDKKYLINLLQRHDELEMDFLASEYRK-HFYISMNHPE 122

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSK---VFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             R   +      + E   LEP  +++          HE    L   I   + + + V  
Sbjct: 123 --RIQPQLFGVDKIIEAMRLEPAKITRNPNALLMQTRHEDKYQLADDIKKDFKEEIEVDS 180

Query: 177 --STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
               L  LE    G++K +AL  + K +  S  D IAFGD  ND EML +A  G  M +A
Sbjct: 181 WGGPLNILEFSPKGINKAYALNYLLKVMRKSTDDLIAFGDEHNDTEMLELAKTGYAMKNA 240

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
              L   H   ++  TN +D V   L++L L
Sbjct: 241 SSVLLP-HANEQIEWTNEEDGVARKLQELLL 270


>UniRef50_B5RRM7 Hydrolase n=20 Tax=Borrelia RepID=B5RRM7_BORRA
          Length = 295

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 79/275 (28%), Positives = 139/275 (50%), Gaps = 21/275 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINF--VFATGRHHVDVG----QIRDN 55
           Y+++  DLDGTLL+  H ++P    TLK+L     +F  + ATGR   ++     Q++D 
Sbjct: 25  YKMLVFDLDGTLLNSKHEITPL---TLKVLLRLRDDFHIIIATGRRLYEIRDILLQLQDL 81

Query: 56  LEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
              + Y++T+NG+ V  L+ +L+   ++D  I  ++F V  +  DI  N+Y   +W+ +R
Sbjct: 82  RINEGYIVTANGSEVF-LNNDLLLRCSIDYGIVREIFKVDREGIDI--NLYDLHDWYSDR 138

Query: 116 --HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINA---RWGD 170
               P    F +    +  + +   L+    SK+ +   SH+ LL LE+  N    +   
Sbjct: 139 EIRSPIMNHFIQNLGIKPIITDLSELKINSCSKIVYY--SHD-LLRLEEFANTLREKNFK 195

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            +++ +S     E+     SK +A++ ++      +   +AFGD  ND EML   GKG +
Sbjct: 196 GISMFYSANDLFEITNVDASKYNAIKNISLCECIGVDSILAFGDNGNDYEMLKNVGKGIL 255

Query: 231 MGSAHQRLKDLHPELEVIG-TNADDAVPHYLRKLY 264
           M +AH R+K+  P  E+    N DD V  +L + +
Sbjct: 256 MKNAHDRVKNSLPNNELTKFCNDDDGVAKFLIEFF 290


>UniRef50_UPI0001788F0C Cof-like hydrolase n=1 Tax=Geobacillus sp. Y412MC10
           RepID=UPI0001788F0C
          Length = 254

 Score = 90.5 bits (223), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 68/261 (26%), Positives = 122/261 (46%), Gaps = 23/261 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLDGTLL+ +  ++   K+ L+    +G+  +F+TGR         D L + S 
Sbjct: 11  YKLIALDLDGTLLTDEKHITDETKKWLQYAVDQGVKVMFSTGRGLQTAKGFWDELGLDSP 70

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           M+  NGA V +  G L     L RD   D+  +            +  EW+         
Sbjct: 71  MVLLNGAEVWEGPGRLKKRVFLPRDAVRDMHAIA----------AKRGEWYWG------- 113

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            +  E++     + P + E + + K     +   +L  +++ + + WG  + V+ S  T 
Sbjct: 114 -YSVESLTGDKDWTPEMFERDWM-KFGIGSNDQRKLAEIKEELLS-WG-TLEVTHSAPTN 169

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +E+   G++K   +  V + LG+S+ D IA GD  NDA++L  AG G  M +  + +K +
Sbjct: 170 MEISVKGITKESGVREVCQTLGFSMSDVIAMGDSDNDAKLLKAAGLGVAMANGEEHIKSI 229

Query: 242 HPELEVIGTNADDAVPHYLRK 262
                +  TN ++ V   +RK
Sbjct: 230 AD--VITATNNENGVAQAIRK 248


>UniRef50_A5Z551 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
           ATCC 27560 RepID=A5Z551_9FIRM
          Length = 275

 Score = 90.5 bits (223), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 79/287 (27%), Positives = 130/287 (45%), Gaps = 41/287 (14%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++VA D+DGTLL  +  LS   K T+K    RGI F F+TGR   ++ ++   +    
Sbjct: 1   MIKLVAMDIDGTLLDSNKNLSEENKTTVKEYEERGIKFTFSTGRIDNELEEVSSKMPYVK 60

Query: 61  YMITSNGARVHDLDGNLIFAHNL----------------DRDIASDLF--GVVNDNPDII 102
           Y I  NGA V D + N +   +L                D D+  +L   GV+      I
Sbjct: 61  YGIMCNGAYVIDFENNKMLYSDLLDMSDVRYIYDTVKAMDMDMMFELQADGVIYSERRCI 120

Query: 103 T-----NVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFF-TCDSHEQ 156
                 NVY  DE+      P E             Y     +P     +FF T +  ++
Sbjct: 121 EDTKRYNVYHIDEFIKKTRVPVE---------NIGEYIASRDKPVAKVNIFFPTAEIRDE 171

Query: 157 LLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGM 216
           ++   + IN       ++S+S  T LE    G +K   L A+A+ LG S+++ +A GD +
Sbjct: 172 VVEKIKDIN------YDLSYSEGTNLEFNVKGTTKAKGLMALAEYLGISIEETMAIGDNL 225

Query: 217 NDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           ND ++L  AG   +M +A   +K L   + +  +N ++ V + +++L
Sbjct: 226 NDVDILKTAGVSVVMYNARDEIKKLGDFITL--SNDENGVAYAIKEL 270


>UniRef50_Q67R81 Haloacid dehalogenase-like hydrolase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67R81_SYMTH
          Length = 257

 Score = 90.1 bits (222), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 70/256 (27%), Positives = 115/256 (44%), Gaps = 9/256 (3%)

Query: 9   LDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS-YMITSNG 67
           +DGTLL  D T+SP  +  +     RGI  + ATGR +       +    +  ++   NG
Sbjct: 1   MDGTLLRSDQTVSPRNQAAVAACLDRGITVLLATGRFYPAAAPYLEYWPGRPIWLAPCNG 60

Query: 68  ARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKE 126
           A++        I    LD D+A ++   + D   I+  VY      +NR     + F + 
Sbjct: 61  AQLFAPGQTEPITQRTLDLDLAVEVLSWI-DRSRIMARVYFTTLALINRMTERTLAFMRR 119

Query: 127 AVFQYALYEPGLLEP--EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEV 184
              Q   YEP L     E  +K+    D  E  + +E  + +RWG R+ V+ S    +E+
Sbjct: 120 LGAQ-CRYEPALASAVTEPPTKIVLMGDPAEMPV-VEAEVRSRWGGRLEVTSSEPDLVEL 177

Query: 185 MAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPE 244
            A G +KG  + A+A +LG       A G+  ND  M+  AG G  + +AH+ +    P 
Sbjct: 178 TAPGATKGEVVRALAARLGIDRTQVAAIGNERNDLSMIHWAGLGAAVANAHEAVLAAVP- 236

Query: 245 LEVIGTNADDAVPHYL 260
             V+  + +D V  ++
Sbjct: 237 -RVVAHHDEDGVGQFI 251


>UniRef50_Q2JQT8 HAD hydrolase, IIB family n=1 Tax=Synechococcus sp. JA-3-3Ab
           RepID=Q2JQT8_SYNJA
          Length = 285

 Score = 90.1 bits (222), Expect = 6e-17,   Method: Compositional matrix adjust.
 Identities = 62/234 (26%), Positives = 112/234 (47%), Gaps = 5/234 (2%)

Query: 8   DLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNG 67
           D+DGT+  P + +S   ++ ++   A G+    ATGR H    +    +     + +  G
Sbjct: 28  DIDGTIAGPSNQVSEPVRQAIQKAKAAGVRVAIATGRMHRSAERFHYAIGADMPLCSYQG 87

Query: 68  ARVHDLDGNLIFAH-NLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKE 126
           A + D D      H +LD  +A +L  V+ D P +  ++Y DD+ ++    P    + + 
Sbjct: 88  ALIRDPDSQKTLKHWSLDWSLAEELLQVLQDQP-VGVHLYIDDQLYLRELSPLSQAYAER 146

Query: 127 AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG-DRVNVSFSTLTCLEVM 185
           +   + +  P     +  +K+    +  E L  L+ ++  R+  +++ ++ S    LE  
Sbjct: 147 SQVPFQMLSPA-QHGKSPTKILAVSEDTEFLQQLQGSLRQRYSPEQIYLTRSEPIFLEAT 205

Query: 186 AGGVSKGHALEAVAKK-LGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              V+KG+A+  +A++ LG S    +A GDG ND EML  AG G  MG+A   L
Sbjct: 206 HAAVNKGNAVRFLAEELLGVSADQVMAIGDGDNDIEMLQYAGIGVAMGNASPAL 259


>UniRef50_A6TMX9 Cof-like hydrolase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TMX9_ALKMQ
          Length = 293

 Score = 90.1 bits (222), Expect = 7e-17,   Method: Compositional matrix adjust.
 Identities = 73/285 (25%), Positives = 129/285 (45%), Gaps = 28/285 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A+D+DGTLL  D  LS    E L      GI+    TGR    V    + L I  +
Sbjct: 3   YKLLATDMDGTLLMDDKALSTENIEALTRGKEHGIDLAICTGRPFPTVKPYLEQLGISCW 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           ++T+NG+ + D   N+I+   +++D    +  +     D+  +V   +  ++ + R + M
Sbjct: 63  LVTNNGSVIRDKQENIIYEKFMEQDALEKIIDIFESEKDLYYHVSDANHTYI-KSRRQRM 121

Query: 122 RFFKEAV-------FQYALYEPGLLEPEG----------------VSKVFFTCDSHEQLL 158
           R  ++ V        +  +    ++   G                V+ VF     + QL 
Sbjct: 122 RTIQKFVSIKNMSPIKAYVTAAKMVFLSGTHKKVDFLSYVKNGGKVASVFVYSKDNIQLN 181

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
            L++ ++      +NV+ S    +E++ G  +KGHALE ++KKL    ++ IA GD  ND
Sbjct: 182 RLKEKLSEI--KSINVTSSGSDNIEILDGNATKGHALEYLSKKLDIQAEEMIAVGDNYND 239

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
             M+  AG G  M +  Q + D      V  TN ++ V   + K+
Sbjct: 240 LSMIQYAGLGVAMRNGEQAIIDEAD--WVTKTNQENGVAFLMEKV 282


>UniRef50_B1BZI7 Putative uncharacterized protein n=2 Tax=Clostridium spiroforme DSM
           1552 RepID=B1BZI7_9FIRM
          Length = 268

 Score = 90.1 bits (222), Expect = 8e-17,   Method: Compositional matrix adjust.
 Identities = 74/270 (27%), Positives = 121/270 (44%), Gaps = 11/270 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQVV SD+DGTLL+  H ++P     +K +  +GI FV  + R    +  I     +  
Sbjct: 1   MYQVVFSDVDGTLLNDQHCITPLTLLAIKKIQQQGIPFVIVSARSPSGIYPILKENNLVC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVN-DNPDIITNVYRDDEWFMNRHRPE 119
            MI   G  + + +  +I+   ++  +A  +   +  +N DI   +Y  D+W +      
Sbjct: 61  PMICYGGGMILNHENEIIYEKGMETSLALKIINYIEANNFDIAWCIYSFDDWLVKDCL-- 118

Query: 120 EMRFFKEAVFQYALYEPG----LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           + R  KE     A    G    + +   V K+   C+ HE +  LE  +   + +   V 
Sbjct: 119 DPRIIKEEQIVRAKSRQGNQIEIKKLSKVHKILCICN-HEHINDLETKLKIMFKECQIVK 177

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S +  +E+    +SK  A++     L  ++K+ IAFGD  ND EML + G G  M +A 
Sbjct: 178 SSNIL-IEITHQNISKAFAIKKYCDLLNINIKNTIAFGDQYNDLEMLKIVGCGIAMKNAP 236

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +K      +V   N  D +   L KL L
Sbjct: 237 LGIK--KEVKQVTKDNNHDGIYFALSKLNL 264


>UniRef50_B2V561 HAD-superfamily hydrolase, subfamily IIB n=14 Tax=Bacteria
           RepID=B2V561_CLOBA
          Length = 293

 Score = 89.7 bits (221), Expect = 9e-17,   Method: Compositional matrix adjust.
 Identities = 72/269 (26%), Positives = 116/269 (43%), Gaps = 34/269 (12%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ SD+DGTLL+ +H +     E ++     GI F  +TGR +  V  I D   I+ 
Sbjct: 1   MIKLIVSDMDGTLLNNNHDIDVETVEAIRKAEEAGIIFTISTGREYDSVKGILDKHNIRC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             I SNGA   D +GN++   N++ + A  +  ++++N  +   ++ D   F    R E 
Sbjct: 61  QCILSNGAEYRDEEGNILEVININEEYAKQIIKILDENK-LPARIFTDKGVFTTSTREEA 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKV----FFTC----DSHEQLLPLEQAINAR----- 167
           ++   E VF+   + P L E E         FFT     D  E+    E  I  R     
Sbjct: 120 LQ---EVVFRTLTFNPNLTEDEAKKMAEKEGFFTSLKYIDDVEKF--FEDGIEVRKFVAF 174

Query: 168 -----WGDRVNVSFSTLTCL----------EVMAGGVSKGHALEAVAKKLGYSLKDCIAF 212
                  D++  +   L  L          E+      KG  LE VAKK+   +KD +  
Sbjct: 175 HKDVELIDKIKKTVGKLEGLAISSSFDDNIEITDLNAQKGIILEQVAKKMDIDIKDVMIL 234

Query: 213 GDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           GD  ND  M  +  +   M +A   +K++
Sbjct: 235 GDSFNDYSMFEIFEESVAMKNAIPEVKEI 263


>UniRef50_B8DEX6 Phosphatase YidA n=17 Tax=Listeria RepID=B8DEX6_LISMH
          Length = 270

 Score = 89.7 bits (221), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 78/276 (28%), Positives = 134/276 (48%), Gaps = 19/276 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGTLL+ DH ++   KE ++    +G+  V  TGR  V V      LE++ 
Sbjct: 1   MYKLIAIDIDGTLLTDDHKVTDEVKEAIRQAKLKGVKVVLCTGRPLVGVENYLTELELRE 60

Query: 61  ---YMITSNGARVHDLDGNLIFAH-NLDRDIASDLFGVVNDNPDIITNV---YRDDEWFM 113
              Y+I+ NGA V D     + +H  L  D   +++ V  D     +N+   + DD+   
Sbjct: 61  EGDYVISFNGAFVQDTFTKEVISHLTLGIDDLKEIYQVSLD-----SNLHMHFFDDKALY 115

Query: 114 NRHRPEEMRFFKEAVFQYA--LYEPGLLEPEG--VSKVFFTCDSHEQLLPLEQAINARWG 169
             +R        EA    +  +Y+     PE   +SK  F  ++ E  + + + I   + 
Sbjct: 116 TPNREIGKYTIVEAYLTGSQLIYKEIENVPEDFIMSKAMFIEEAPELEVGIAK-IPESFR 174

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           ++ ++  ST   LE++    SKG+A++ +++K+G    + +  GD  ND  ML  AG G 
Sbjct: 175 EKYHLVRSTPFYLEILNRDASKGNAVKELSEKIGIKQSEVMCIGDQENDVTMLEFAGLGI 234

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            MG+A +R+K L        +N D  V   ++K  L
Sbjct: 235 AMGNAPERIKQLAD--YTTASNNDSGVAKAIQKFVL 268


>UniRef50_Q1WS49 Hydrolase, HAD superfamily n=2 Tax=Lactobacillus salivarius
           RepID=Q1WS49_LACS1
          Length = 277

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 67/247 (27%), Positives = 117/247 (47%), Gaps = 9/247 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY++VA D+D TLL+ D  +SP     LK     G+  V  TGR ++ V +    L I  
Sbjct: 1   MYKLVAIDMDETLLNDDAEISPKNVSVLKKAIKDGVKVVLNTGRSYLSVQENLKTLGIYQ 60

Query: 59  --KSYMITSNG-ARVHDLDGNLIFAHNLDRDIASDLFGV-VNDNPDIITNVYRDDEWFMN 114
               Y+++ NG A V + D  ++    L  DI   LF + +   P+   +VY  DE +M 
Sbjct: 61  TKDQYVVSFNGGAIVENKDLKVVHVEGLTFDIVKQLFDISLRYYPESCIHVYTLDELYMW 120

Query: 115 RHRPEEMRFFKEAVFQYA-LYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
               +E  + +    ++  L EP +  LE   ++K+    +  ++ L   +      GD+
Sbjct: 121 NVNQDEKDYLQPRGVEWTELQEPNIDFLEDTPITKIIINVNDMDKRLAFNEIARKEIGDK 180

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
              ++S+   +E       KG  +  +A+ LG   ++ IA GD  ND  M+  AG G  +
Sbjct: 181 FKTTYSSGRYIEFNNISTDKGTGMLKLAEMLGIKPEETIAIGDNSNDLPMIEAAGVGVAV 240

Query: 232 GSAHQRL 238
            +A++++
Sbjct: 241 RNANEQV 247


>UniRef50_A7AZV2 Putative uncharacterized protein n=1 Tax=Ruminococcus gnavus ATCC
           29149 RepID=A7AZV2_RUMGN
          Length = 257

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 77/267 (28%), Positives = 119/267 (44%), Gaps = 17/267 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASDLDGTLL  D ++S Y  + +K   A GI +V  TGR       I +N  +  
Sbjct: 1   MIRMIASDLDGTLLRKDWSISEYTIKIIKEAQASGIRWVTVTGRSDRGARPIMENYGLSC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF-MNRHRPE 119
             I  NGA   D +GNLI + N+D D+A            +   ++R++  F +N  R +
Sbjct: 61  DYILMNGAEFRDTNGNLIKSENIDTDLAR----------FVCEKLHRENLGFEINTDRGD 110

Query: 120 EMRFFKEAVFQYAL---YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                + A +   L   YE    E   + K+   CD   ++  ++Q I    G  V  SF
Sbjct: 111 YTTTMELAEYSDYLEDGYEKLFEEKHNIRKILVFCDDIPKIRRIKQQIYDASGLSVLSSF 170

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
                +EV +    KG  L+   K  G+  ++ + FGDG ND  M         M +   
Sbjct: 171 E--NNMEVTSQKAKKGIMLKQAMKHFGFLPEEVVVFGDGENDISMFQEFPCSYAMINGVD 228

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKL 263
            LK+L   +    +N +D V   L K+
Sbjct: 229 ALKELAYRVTEY-SNDEDGVAKTLEKI 254


>UniRef50_A8SLC7 Putative uncharacterized protein n=1 Tax=Parvimonas micra ATCC
           33270 RepID=A8SLC7_9FIRM
          Length = 286

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 77/279 (27%), Positives = 128/279 (45%), Gaps = 28/279 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGT  + +H +S   K++L    ++G+   F +GR    V +I  NL + +
Sbjct: 19  MYKLIALDMDGTTFNENHEISDEVKDSLFYAMSKGVKIAFISGREEFTVKEILKNLNLDT 78

Query: 61  YMITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDN--------PDIITNVYRDDEW 111
           Y    NG+ +      +  F  +L++    D+  ++ +N         D I     +DE+
Sbjct: 79  YYGALNGSLISTTYSEVPKFVKSLEKKYIFDVLDIIENNGFSPIIFLKDFIFTKDSNDEY 138

Query: 112 ------FMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN 165
                 F+N   PE  R   + V QY   +   LE E V K+   C  ++ L  L+    
Sbjct: 139 VEIISKFIN---PEIARV--KDVKQYI--KDNKLE-EKVLKIGI-CQEYDVLKELDDKFT 189

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
               +   +SFS    LE+MA    KG  L  + +     + + IA GDG ND  ML++ 
Sbjct: 190 NTIKNEYTISFSLPFFLELMAKDTDKGSCLREICRLNNIDISETIAMGDGENDIPMLNIC 249

Query: 226 GKGCIMGSAHQRLKDLHPELEVIG-TNADDAVPHYLRKL 263
           G    MG+A + +K     ++ I  TN +D V   +RK 
Sbjct: 250 GLSIAMGNAMENVK---KNVDYITDTNKNDGVAKAIRKF 285


>UniRef50_UPI0001788505 Cof-like hydrolase n=1 Tax=Geobacillus sp. Y412MC10
           RepID=UPI0001788505
          Length = 292

 Score = 89.4 bits (220), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 73/272 (26%), Positives = 126/272 (46%), Gaps = 20/272 (7%)

Query: 7   SDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSN 66
           +DLDGTLL  D TLSPY    +     R +   +AT R ++    +  ++  K  +I  N
Sbjct: 8   TDLDGTLLRSDQTLSPYTMNVVTDALERDLIVTYATARGYISAQSVVSDIPWKYPVILYN 67

Query: 67  GARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFK 125
           GA ++D L+  ++  + L+RDI++++ GV   +  I    +  D+    R   E +R   
Sbjct: 68  GALIYDGLNQTVVDGYWLERDISNEIIGVGKKH-GITPFYFSLDKDQRERVLHETLRREG 126

Query: 126 EAVFQYA--LYEPGLLE-------PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS- 175
           E  F YA   ++P  LE       P+  +        HE+L P+ Q + A +GD ++   
Sbjct: 127 EMTF-YAGRPHDPRFLEVKNLKCPPDYRTLALTYIGLHEELEPIRQEVTAFYGDVIHAHM 185

Query: 176 -----FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
                      LE      +K   L+  +  +G  L++ + FGD +ND  +    G    
Sbjct: 186 MPDYYIRNHYFLEFSHAKANKRDGLQLWSAHMGIDLENTVVFGDHINDVGLFEAGGTRIA 245

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRK 262
           + +AH+R++ L     +I +N  D V HY+ +
Sbjct: 246 VRNAHERIRQLAD--HIIDSNELDGVAHYIEQ 275


>UniRef50_C4RHE6 HAD-superfamily hydrolase, subfamily IIB n=2 Tax=Micromonospora
           RepID=C4RHE6_9ACTO
          Length = 271

 Score = 89.0 bits (219), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 78/267 (29%), Positives = 119/267 (44%), Gaps = 10/267 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VA+D+DGTLL+ + TLSP  ++ L  ++ARG   V  TGR    +  +   L      
Sbjct: 7   RLVATDIDGTLLTDERTLSPRTRDALARMSARGTPVVLVTGRPIRWLQLVYQQLAEPLPA 66

Query: 63  ITSNGARVHDLDGNLIF-----AHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
           I +NGA V+D   + +      A  L  ++A  L   V   P +   V   D   M    
Sbjct: 67  ICANGAVVYDPVTDEVLRADPLAPKLLAEVARRLRAEV---PGVSFAVEIVDSREMRHET 123

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
              +R+  +A    A+  P  L      K+       +  + LE    A  G       S
Sbjct: 124 DYPLRWDADAEAIRAITSPEELHSVPAVKLLARAGEQDPDVFLEVVAGALRGLAEATHSS 183

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               +E+ A GV+K   L     +LG   +D +AFGD  ND  ML+ AG+G  + +AH  
Sbjct: 184 YTGLVEISAAGVTKAAGLAWYCARLGIDERDVLAFGDMPNDVPMLTWAGRGVAVANAHPA 243

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLY 264
           +  L    EV   N++D V  YL K++
Sbjct: 244 V--LAIADEVTAANSEDGVAAYLEKVF 268


>UniRef50_C5EF13 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C5EF13_9FIRM
          Length = 273

 Score = 89.0 bits (219), Expect = 1e-16,   Method: Compositional matrix adjust.
 Identities = 67/239 (28%), Positives = 112/239 (46%), Gaps = 10/239 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ SD+DGTLL+  H +    ++ +  L   G+ FV  + R    +  I+  +  ++ 
Sbjct: 10  YKMIFSDIDGTLLNSGHQVPEPTRKKILELEKEGVPFVLVSARMPEGMTTIQAMIGNRAP 69

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIA---SDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
           M+  +GA + D DGN +++  +D D+A    DL G   + P+I  N Y    W ++    
Sbjct: 70  MVCYSGALIRDADGNTMYSCQMDLDLAVRIKDLIG--KEFPEICCNTYGGSRWVVDDDSS 127

Query: 119 EEMRFFKEAVFQYAL---YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             +R  +E     A+            GV K F      E +  LE+ +   + D ++++
Sbjct: 128 PWVRKEEEITGLKAMNGDIREVFTADRGVHK-FLLMGQEEAVQGLEKRLKEHFPD-LSIA 185

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
            S+   LEVM G VSK   +  +    G  L + IAFGDG ND +ML        M +A
Sbjct: 186 SSSPVYLEVMDGRVSKSRGVGFLCSHYGVGLDEVIAFGDGCNDMDMLRAVKNSYAMANA 244


>UniRef50_Q819K1 Hydrolase (HAD superfamily) n=77 Tax=Bacillaceae RepID=Q819K1_BACCR
          Length = 257

 Score = 89.0 bits (219), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 69/243 (28%), Positives = 114/243 (46%), Gaps = 16/243 (6%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V  D+DGTLL  D  +    ++ +K L  +G++   ATGR       IR  L+I +Y 
Sbjct: 4   KIVFFDIDGTLLDHDKKIPQSTRDAVKQLQEKGVHVAIATGRAPFMFEDIRKELDIHNY- 62

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ++ NG  V   +  +IF + L  D               +  VY D +    R   E   
Sbjct: 63  VSFNGQYV-VFEDEVIFNNPLHPDALHKFTQFAKQEGYPL--VYLDHQDM--RASVEYHD 117

Query: 123 FFKEAV----FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           + KE      F++  YEP   E   + +    C+ +E+    E+ IN  + D   + +  
Sbjct: 118 YVKEGFGSLNFEHPAYEPNFYEERNIYQTLLFCEVNEE----EKFIN-HYPDFHFIRWHA 172

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
            + ++++  G SK   +E   +KLG++     AFGDG+ND EM+   G G +MG+ H+ L
Sbjct: 173 YS-MDIIPNGGSKAKGIEKYIEKLGFNRDQVYAFGDGLNDLEMIEAVGTGIVMGNGHEDL 231

Query: 239 KDL 241
           K L
Sbjct: 232 KKL 234


>UniRef50_B9DTI8 Haloacid dehalogenase-like hydrolase n=1 Tax=Streptococcus uberis
           0140J RepID=B9DTI8_STRU0
          Length = 272

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 64/273 (23%), Positives = 132/273 (48%), Gaps = 11/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGTLL  D +++  +  ++K     G   V ATGR   ++   +  L    
Sbjct: 1   MYKLIAFDMDGTLLQSDKSIAETSLSSIKDAFQNGKEVVLATGRPKSELHMYQKELSNIR 60

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
           Y I  +GA V+D ++  ++    + +DI+  ++ +V  N D++  +  D + ++ +   +
Sbjct: 61  YGILESGAIVYDFVNDKVLMKEVIPKDISDKVYDIVQTN-DVMVVLMIDGQGYIQQDHFD 119

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQL-------LPLEQAINARWGDRV 172
            +  +  ++++    +  +   E + K+       E++       +  +        + V
Sbjct: 120 HIADYHMSIYEDLYQDSAIFLDEILPKMETEAGQFEKINLYFKTNVLRDHYYKVLSNENV 179

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            ++ +  T +E+ A GV KG  L+ + + LGYS+ + IA GD  ND  M+  AG G  M 
Sbjct: 180 TLAKAEETAIEITARGVEKGQGLKKLCQILGYSIVEAIAVGDADNDESMIRDAGLGVAMA 239

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +A+Q +K L     ++ +N +  +   + K  L
Sbjct: 240 NANQNIKKLAD--VIVSSNDNGGIQEVIEKFLL 270


>UniRef50_C1C848 Hydrolase n=29 Tax=Streptococcus RepID=C1C848_STRP7
          Length = 275

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 77/260 (29%), Positives = 118/260 (45%), Gaps = 22/260 (8%)

Query: 1   MYQVVASDLDGTLLSPDHTLS-PYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK 59
           M +V+A+D+DGTLL     L  P  ++ L  L  RGI FV ATG     + Q+   L  +
Sbjct: 2   MIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIATGNEIHRMRQLLSPLVDR 61

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIAS------------DLFGVVNDNPDIIT--NV 105
             ++ +NGAR+ + +  LI A   D  I +            D F V     D +    +
Sbjct: 62  VVLVVANGARIFE-NNELIQAQTWDDAIVNKALAHFKGRACQDQFVVTGLKGDFVKEGTI 120

Query: 106 YRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN 165
           + D E FM     E  +F++   F   L         GV K+       E+L  + + IN
Sbjct: 121 FTDLESFMTPEMIE--KFYQRMQFVDELTSDLF---GGVLKMSMVV-GEERLSSVLEEIN 174

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
           A +  RV    S   C++++  G+ K   LE + K+     ++ +AFGD  ND EML MA
Sbjct: 175 ALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEIMAFGDSENDVEMLEMA 234

Query: 226 GKGCIMGSAHQRLKDLHPEL 245
           G    M +A ++ K +   L
Sbjct: 235 GIAYAMENADEKAKAVATAL 254


>UniRef50_A8U9P8 Hydrolase, haloacid dehalogenase-like family protein n=1
           Tax=Carnobacterium sp. AT7 RepID=A8U9P8_9LACT
          Length = 269

 Score = 88.6 bits (218), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 79/276 (28%), Positives = 124/276 (44%), Gaps = 17/276 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL---E 57
           M ++VA DLDGTLL+ +H +S   KE +K    +G+  V  TGR  + +    + L   E
Sbjct: 1   MIKLVAIDLDGTLLNREHIISDENKEVIKKAKEQGVKVVLCTGRPLLGMISYLEELNLRE 60

Query: 58  IKSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           +  Y IT NG  V   D G ++    L +    ++F + +   ++  N + D E      
Sbjct: 61  VGDYGITYNGGLVQRTDTGEVLSKKTLTKVEIEEIFAL-SKEINVPCN-FIDLEKIYEPP 118

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVS------KVFFTCDSHEQLLPLEQAINARWGD 170
            PE        V +   Y P  +E E VS      K  F C     L    + I   + +
Sbjct: 119 YPEGRDSLYPTVMRALPYVP--IEMEHVSEDIAINKTVF-CYEQTSLDEAIKKIPVHFHE 175

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           +  +  S    LE+M  GV KG  +  +A  LG+   + ++ GD  NDA M+  AG G  
Sbjct: 176 KYTIMKSRPVLLELMPKGVDKGSGIAVLADLLGFEASEVMSLGDEANDAAMIEYAGMGVA 235

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           MG+A   +K +     +  TN +  V H ++K  L+
Sbjct: 236 MGNATDEIKAMAQ--YITKTNEEHGVAHAIQKFVLN 269


>UniRef50_A8UDR5 Putative hydrolase, haloacid dehalogenase family protein (Fragment)
           n=1 Tax=Carnobacterium sp. AT7 RepID=A8UDR5_9LACT
          Length = 260

 Score = 87.8 bits (216), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 76/257 (29%), Positives = 119/257 (46%), Gaps = 9/257 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGT L+    +S   +  L  L   G      TGR + +  Q    L +++ +
Sbjct: 4   KLIALDLDGTTLNNRSEISARTQNVLTTLRNDGHLVSIVTGRPYRNSKQFYTQLGMETPI 63

Query: 63  ITSNGARVH---DLDGNLIFAHNLDRDIASDLFGVVND-NPDIITNVYRDDEWFMNRHRP 118
           +  NGA  H    L+    +   LDR+IA D+  +  + +  +I    RD  +  N   P
Sbjct: 64  VNFNGALCHLPNQLNWESQYHKTLDREIALDMLTLKKELDIHLIAAELRDTVFADNYFVP 123

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF-- 176
               FF E     +      L+ +  +   FT D+  Q   +E+ I+AR+G+ V +    
Sbjct: 124 YS-DFFPEGKKGASKLTASSLKEDPTAICVFT-DAENQAHIIEK-ISARYGNTVEIRTWG 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
               CLE++A GV K   +E +AK  G   KD IAFGD  ND EM+  AG G +M +   
Sbjct: 181 GQTPCLEIVAAGVQKALGVERIAKVYGIKQKDIIAFGDEDNDYEMIQYAGHGVVMKNGID 240

Query: 237 RLKDLHPELEVIGTNAD 253
            LK +  ++     N D
Sbjct: 241 ALKRISNDVTEKTNNED 257


>UniRef50_B2THH0 HAD superfamily hydrolase n=3 Tax=Clostridium botulinum
           RepID=B2THH0_CLOBB
          Length = 270

 Score = 87.8 bits (216), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 69/262 (26%), Positives = 122/262 (46%), Gaps = 12/262 (4%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++ SD+DGTLL  D  LS   K+ +    ++G NF  ATGR     G+  +++ +   +I
Sbjct: 9   LLISDMDGTLLDSDGKLSYENKKAIDYFISKGGNFTLATGRIVASAGRFLNDINVTLPVI 68

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVV-NDNPDIITNVYRDDEWFMNRHRPEEMR 122
             NGA+++D   N I       D   +   +V  DNP +   VY +++ ++        R
Sbjct: 69  LYNGAKIYDYKNNKIIYEEFIEDYRKNTITLVKKDNPTLGIEVYSEEKVYIYSSCKYTDR 128

Query: 123 FFK---EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
           F K   E ++      P     +  +KV    +  E +  LE+     +GD  N+  S  
Sbjct: 129 FSKLGYEVIYNL----PTEAWNKKWTKVIIVGEEDE-IDSLEENFIRNYGDG-NIIRSGA 182

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             LE++    SKG A+E +        ++ I  GD MND EM+ +A  G  + S  +RL 
Sbjct: 183 RYLEIVPNNTSKGKAIEKLMDVYNIKSQNLITIGDNMNDIEMIKLADYGFCVRSGAERL- 241

Query: 240 DLHPELEVIGTNADDAVPHYLR 261
            ++    +  +N ++A+ + ++
Sbjct: 242 -INNSKFIAPSNDENAIDYVIK 262


>UniRef50_B7C7C0 Putative uncharacterized protein n=1 Tax=Eubacterium biforme DSM
           3989 RepID=B7C7C0_9FIRM
          Length = 277

 Score = 87.8 bits (216), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 78/267 (29%), Positives = 125/267 (46%), Gaps = 14/267 (5%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK---S 60
           ++A+DLDGT L+    ++   KE +  L   GI F  A+GR    V  +    +I+   S
Sbjct: 6   LIATDLDGTFLNSKKQVTSLNKEAVSKLKQYGILFGIASGRPIETVRAMLKEWKIEDSVS 65

Query: 61  YMITSNGARVHDLDGNLIFA-HNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR---H 116
           +++  NG  ++DL        H LD ++  D+     D  D+   +      + NR    
Sbjct: 66  FIMGMNGGVLYDLRQRTKEEYHLLDGEVVLDIIHFFED-LDVDFWILEGATRYTNRTSIE 124

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             E  R F E   +  L EP LL     +K+   CD     + LE+A   ++ +   V F
Sbjct: 125 TQEHARIFGETEIEIDL-EPYLLN-NTCNKLIIHCDKEYMPIVLERA--KQYKNEACVGF 180

Query: 177 STLTCL-EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            T   L E +   ++KG+ +E VAK  G  L++C+AFGD  ND EML   G G  M +  
Sbjct: 181 LTADNLFEYVDPRINKGYGIEKVAKHFGVKLENCVAFGDEQNDMEMLQKVGMGVCMKNGS 240

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRK 262
           +++KD    +    TN + AV  ++ +
Sbjct: 241 KQVKDCGAFVSAY-TNDESAVARFIEE 266


>UniRef50_Q5WG82 HAD superfamily hydrolase n=1 Tax=Bacillus clausii KSM-K16
           RepID=Q5WG82_BACSK
          Length = 246

 Score = 87.4 bits (215), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 68/264 (25%), Positives = 120/264 (45%), Gaps = 30/264 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGTLL+ +  ++ + K  ++     GI  V  TGR          +L++ S+ 
Sbjct: 5   KMIALDIDGTLLNDNKEITSWTKNQIRKAQHAGITVVLCTGRPFPHCHTYIQDLQLHSHS 64

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           IT NG +++ +D +++  H  D    ++L+                       H  + + 
Sbjct: 65  ITCNGGQIYAVDHSVMIEHLFDAATLANLY-----------------------HFAQGLG 101

Query: 123 FFKEAVFQYALYEPGLLEPEGVSK---VFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
                +     Y   L  PE  S    + F+C   ++ +  + A   +  D V VS  T 
Sbjct: 102 MNTWTISTKEAYYNDL--PENCSAYQWLKFSCSHKDEEVLNKMAEKVQSIDGVEVSNRTA 159

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +EV   GV+K  ALE V +KLG ++K  +A GD +ND +M+  AG G  MG+A + ++
Sbjct: 160 FTVEVNPTGVNKAAALEWVCEKLGITMKHVMAIGDSLNDIKMIQSAGIGIAMGNAQKAVQ 219

Query: 240 DLHPELEVIGTNADDAVPHYLRKL 263
            +     +  TN +D V   + K 
Sbjct: 220 QVAD--AITDTNNNDGVGKAIEKF 241


>UniRef50_B0N4M8 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B0N4M8_9FIRM
          Length = 272

 Score = 87.0 bits (214), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 72/255 (28%), Positives = 117/255 (45%), Gaps = 30/255 (11%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
           Y+++A DLDGTL S D  + P  K  L+ L  RG+  V A+GR    +    + LE+   
Sbjct: 3   YKLIALDLDGTLKSTDKQILPKTKAILQELAKRGVVIVLASGRPTAGLYAEANELELDKT 62

Query: 61  --YMITSNGARVHDLDGN-LIFAHNLDRDIASDLF--------GVVNDNPDIITNVYRDD 109
             Y+++ NGA+V D     +I+    D   A  ++         V+    ++I      D
Sbjct: 63  GGYLLSFNGAKVVDYKTKEIIYQKVYDAKTAHQVYERAKQYNLAVMTYTDELILTEDETD 122

Query: 110 EWF-----MNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAI 164
           E+      +N    + +  FK+AV               V+KV  T         L++  
Sbjct: 123 EYVCIEGDINHMPIKHIDNFKDAV------------NFSVNKVLLTAKPEYAETILDE-F 169

Query: 165 NARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSM 224
            A +GD +++  S    +EVMA G+ K  +L+A+ ++LG    + I+FGDG ND  M+  
Sbjct: 170 KAPYGDSLSIYRSAPFFIEVMAQGIDKAASLQALIERLGIKRDEVISFGDGYNDLSMIEF 229

Query: 225 AGKGCIMGSAHQRLK 239
           A  G  M +A   +K
Sbjct: 230 AKFGVAMANAVDEVK 244


>UniRef50_A7VTJ0 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VTJ0_9CLOT
          Length = 274

 Score = 87.0 bits (214), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 83/277 (29%), Positives = 128/277 (46%), Gaps = 21/277 (7%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  +  SDLDGTLL+P+  +S  + + L  L  +G+ F  AT R      ++  NL+++ 
Sbjct: 1   MKTLYVSDLDGTLLTPEKEISKASADILNHLIQKGLLFTVATARSPATACEVLSNLKLEL 60

Query: 61  YMITSNGARVHDLDGNLIFAHN--LDRDIASDLFGVVNDN---PDIITNVYRDDEWFMNR 115
             I  NGA ++D      FA +  +  + AS    V       P + T    DDE  ++ 
Sbjct: 61  PGILLNGAVLYDFRRRR-FAGSAPMSYEAASKALAVYRQAGRMPFLYT--LEDDEICVSY 117

Query: 116 HR---PEEMRFFKEAVFQ-YALYEPG--LLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
            R   P E RF +E   + Y  +E    +L P+ V   F   D    + PL + I    G
Sbjct: 118 ERFGHPAEERFCQERKGKAYKRFEQRELVLSPKDVPIYFTMMDKRTVVEPLYRKIQQIPG 177

Query: 170 DRVNV---SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
            +      ++  +  LEV +   SK  A+  + + LG      +AFGD  ND +ML+ A 
Sbjct: 178 LKAAFYHDNYEDVYFLEVFSSQASKSLAVLRLKEMLGAG--RVVAFGDNGNDVDMLAAAD 235

Query: 227 KGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            GC +G+A    K      ++IG+N +D V  YLR L
Sbjct: 236 VGCAVGNASPEAKAAAD--QIIGSNTEDGVAEYLRPL 270


>UniRef50_C2EN69 HAD family hydrolase n=7 Tax=Firmicutes RepID=C2EN69_9LACO
          Length = 272

 Score = 87.0 bits (214), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 75/260 (28%), Positives = 130/260 (50%), Gaps = 13/260 (5%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           MY+++A DLD TLL     +    K+ ++  T  G+ FV ATGR +  + Q  D + +K 
Sbjct: 1   MYKLIACDLDETLLDDHAHVCQRNKDAIEAATKLGVKFVPATGRGYNAIAQTLDEINLKD 60

Query: 60  ---SYMITSNGARVHDLDGNLIFA-HNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I+ NG  + +  GN I     L  D A++L+ +     ++  +VY  D  ++  
Sbjct: 61  KANEYVISFNGGCITENKGNRIMKFQGLSWDKANELYQL-GLKYNVCIHVYTKDMLYVYH 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
              EE+ + K       + +  L  L+ + ++KV +       L  +   I++   D ++
Sbjct: 120 ADEEELNYIKLRHAYQIIDDQDLDFLKGQEIAKVLYGNPDVPYLEKIANEISSSTKD-LD 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           VS+S+   LE    GV+KG  L  +A KLG  L++ +A GD  ND  M+  AG G  + +
Sbjct: 179 VSYSSNRYLEFNHQGVNKGAGLIWLANKLGIKLEETMALGDNFNDLSMIKAAGLGVGVAN 238

Query: 234 AHQRLKDLHPELEVIGTNAD 253
            + ++K+   E + + TNAD
Sbjct: 239 VNPQMKN---ECDFV-TNAD 254


>UniRef50_P42962 Uncharacterized protein ycsE n=9 Tax=Bacillus RepID=YCSE_BACSU
          Length = 249

 Score = 87.0 bits (214), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 67/266 (25%), Positives = 127/266 (47%), Gaps = 30/266 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGTLL+ +  +S   ++ ++    +G+  V +TGR  +   ++ ++L++ S++
Sbjct: 11  KLIAIDMDGTLLNDEQLISDENRKAIREAEDKGVYVVISTGRTLMTCRELAESLKLSSFL 70

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           IT+NG+ + D + NL+    L  D    ++                     N+H      
Sbjct: 71  ITANGSEIWDSNFNLVERKLLHTDHIQMMWD------------------LRNKHNT---N 109

Query: 123 FFKEAVFQYALYEPGLLEPEGVSK---VFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
           F+   V +    E     PE ++    + F  D  +  +  E     R    + ++ S+ 
Sbjct: 110 FWASTVNKVWRGEF----PENITDHEWLKFGFDIEDDDIRNEVLEELRKNKELEITNSSP 165

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           T +EV A G++K  AL  V +KLG+++++ +A GD +ND  M+  AG G  MG+A   +K
Sbjct: 166 TNIEVNALGINKAAALAKVTEKLGFTMENVMAMGDSLNDIAMIKEAGLGVAMGNAQDIVK 225

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
           +      +  TN +D V   +R   L
Sbjct: 226 ETAD--YITDTNIEDGVAKAIRHWVL 249


>UniRef50_C2BEV0 HAD superfamily hydrolase n=1 Tax=Anaerococcus lactolyticus ATCC
           51172 RepID=C2BEV0_9FIRM
          Length = 272

 Score = 87.0 bits (214), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 79/283 (27%), Positives = 131/283 (46%), Gaps = 32/283 (11%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL---E 57
           M +++A D+DGTL++ +  ++   +E L   +  G   +  +GR    + +    L   E
Sbjct: 1   MKKLIAVDVDGTLVNSEGVITARTREALIAASKAGHEVMIVSGRPTYGLREQAKALAFDE 60

Query: 58  IKSYMITSNGARVHDLDGNLIFA-HNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
               + + NG +++D   + I   H +D D+A ++    + + D+I          M  H
Sbjct: 61  FGGILSSYNGGQLYDFKADTILVNHPMDFDLAKEILEF-SKSLDLI---------LMVPH 110

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPE--GV-----------SKVFFTCDSHEQLLPLEQA 163
              E+ F  +A   Y+  E G+L+ E  GV           +K+ F  D  +   P    
Sbjct: 111 G--EVIFTDDAENFYSSRESGMLKMEVRGVRDIRDSLDFAPNKLLFAQDPDKLDAPCAN- 167

Query: 164 INARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLS 223
           I  ++GDR     S     EVM  G+SKG ++    K  G  +KD I FGD MND  M  
Sbjct: 168 IREKFGDRTEQVKSARFYYEVMPMGLSKGSSIIEACKIFGIDIKDTIVFGDEMNDMSMFE 227

Query: 224 MAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +AG G  MG+A + +K++     V  TN +D + +YL K  L+
Sbjct: 228 VAGTGVAMGNAVEPVKNVAD--FVTKTNNEDGIAYYLEKFVLN 268


>UniRef50_Q56637 ORF2 n=2 Tax=Vibrio cholerae RepID=Q56637_VIBCH
          Length = 173

 Score = 86.7 bits (213), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 46/142 (32%), Positives = 81/142 (57%), Gaps = 16/142 (11%)

Query: 2   YQVVASDLDGTLLSPDHTLS--------PYAKETLKLLTARGINFVFATGRHHVDVGQIR 53
           Y++VASDLDGTLL+P+H L           A++ L L + + +  + + G        +R
Sbjct: 10  YKIVASDLDGTLLAPNHQLKRIFETDFETAARKDLPLFSRQAVTTLMSRG--------LR 61

Query: 54  DNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM 113
           +   I +YMITSNGARVHD +  L+++ N+ +D+   +  VV  +  +  ++YR+DEW +
Sbjct: 62  EIAGIPAYMITSNGARVHDQNDQLMYSKNVPQDLVQAIIDVVKHDKQLFVHLYRNDEWML 121

Query: 114 NRHRPEEMRFFKEAVFQYALYE 135
           N+       F +++ F Y +++
Sbjct: 122 NKEDEILRDFHEDSGFTYRVFD 143


>UniRef50_A7Z8Z6 Putative uncharacterized protein n=2 Tax=Bacillus
           RepID=A7Z8Z6_BACA2
          Length = 295

 Score = 86.7 bits (213), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 74/263 (28%), Positives = 118/263 (44%), Gaps = 28/263 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +V+A DLDGTLLS + T+       LKL   +G     ATGR   D   I +  ++   +
Sbjct: 2   KVIAIDLDGTLLSENLTIQEQDVRALKLGQKQGHLVTIATGRALFDAKHIINKYDLDFPI 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I SNGA++ D+   +IF H +D D+   +   +N   +I   +Y  D+  ++    +++ 
Sbjct: 62  IASNGAQI-DVGNQVIFEHFMDSDVIQPIITWLNKE-EIYYQLYLSDKIAVSNQGIQQLE 119

Query: 123 -----------FFKEAVF---------QYALYE-PGLLEP---EGVSKVFFTCDSHEQLL 158
                       F + VF         QY L E PG ++P     V K      +  +L 
Sbjct: 120 KELYNTVMEEPHFNQEVFWNSIKAQIHQYGLEEIPGTIDPIDYRYVIKCMIVSPNQRKLK 179

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
             ++           V+ S    LE+ + GV KG +L  + +  G   ++ IA GD +ND
Sbjct: 180 KAKEYFGQL--KECAVTSSGAFNLEITSAGVDKGASLNKLCEHYGTDARNAIAIGDNLND 237

Query: 219 AEMLSMAGKGCIMGSAHQRLKDL 241
             M   AG G  MG+A ++L  L
Sbjct: 238 LPMFHAAGIGIAMGNADKKLIQL 260


>UniRef50_A0R632 Cof-like hydrolase n=33 Tax=Corynebacterineae RepID=A0R632_MYCS2
          Length = 274

 Score = 86.7 bits (213), Expect = 8e-16,   Method: Compositional matrix adjust.
 Identities = 76/276 (27%), Positives = 126/276 (45%), Gaps = 26/276 (9%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A+D+DGTLL  D  ++P  +  ++   A G  FV ATGR    +  + D L +    +
Sbjct: 9   LIATDVDGTLLDEDERVTPRTRAAVRAAVAAGATFVLATGRPPRWIQPVVDGLGLAPMAV 68

Query: 64  TSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR-----HR 117
            +NGA ++D   + ++ A  L  ++ ++L        DI T+V       + R     H 
Sbjct: 69  CANGAVIYDPATDRIVSARTLSPEMLAELA-------DIATHVIPGAGLAVERVGRSAHD 121

Query: 118 PEEMRFFKEAVFQYALYEPG--------LLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
               +F     +++A   P         LL    V  +     +    +  E  +    G
Sbjct: 122 AATPQFVSSPGYEHAWLNPDNTEVSVEDLLSAPAVKLLIRKAGAQSADMAAE--LVKHIG 179

Query: 170 DRVNVSFSTLTCL-EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
            + ++++ST   L E++  G+SK   +  +A  LG +  D +AFGD  ND  MLS AG+G
Sbjct: 180 AQGDITYSTNNGLIEIVPSGISKATGVAELAGPLGLTDADIVAFGDMPNDVPMLSWAGRG 239

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             MG+AH   K      EV  TNA+D V   L + +
Sbjct: 240 VAMGNAHPEAKAAAD--EVTTTNAEDGVATVLERWW 273


>UniRef50_C1I280 HAD hydrolase n=1 Tax=Clostridium sp. 7_2_43FAA RepID=C1I280_9CLOT
          Length = 280

 Score = 86.3 bits (212), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 75/280 (26%), Positives = 129/280 (46%), Gaps = 23/280 (8%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  D+DGTLL+  H +S   KE LK   + G+     TGR         D + I S +
Sbjct: 6   KLICIDMDGTLLNSKHEISERNKEALKKANSLGVKIAITTGRLFCSARYYADLIGIDSPV 65

Query: 63  ITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVND-----NPDIITNVYRDDE------ 110
           I SNGA + H  D   I  + + ++IA +++ +V       N +    + R+DE      
Sbjct: 66  IGSNGAYIKHKYDDIAILENPIPKNIAIEIYKIVKKHGLTVNFNSWDTLIREDEVPATHA 125

Query: 111 -WFMNRHRPEE--MRFF--KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN 165
              MN+  P++  ++F    + +     ++  +L+  G+  V    ++ + L   +  + 
Sbjct: 126 YTIMNKDLPDDKKVKFIVNSDVIETINNFDGKILK--GI--VIEEAENKDNLWAAKDELK 181

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
             +GDR++V  S     EVM G  SKG+A+  +A     + ++ +  GD  ND  ML  A
Sbjct: 182 ETFGDRLHVVSSGTDNFEVMVGTTSKGNAVAHLADTFNINPEEVMCIGDSENDISMLKFA 241

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G    MG+  Q +KD+     V  TN +D V   +    L
Sbjct: 242 GVSVAMGNGLQMVKDIAD--FVTDTNNNDGVAKAIEMFVL 279


>UniRef50_B9CMS8 HAD-superfamily hydrolase, subfamily IIB family n=1 Tax=Atopobium
           rimae ATCC 49626 RepID=B9CMS8_9ACTN
          Length = 306

 Score = 86.3 bits (212), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 74/249 (29%), Positives = 124/249 (49%), Gaps = 16/249 (6%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +V SD+D TLLS D ++S    E L  L  +GI FV  +GR    +           Y I
Sbjct: 35  IVFSDMDDTLLSNDKSISDKNLEVLDYLAKQGIPFVPTSGRALSLLPHEVLAHPASRYAI 94

Query: 64  TSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           T++GA V+DL    +++  ++ ++ A  LF ++ D P +  +V+     + +  R E+M+
Sbjct: 95  TADGATVNDLRTEEVLYKSHVKKEDALALFELMKDLP-VTFDVFSGGRAYTDNARREQMK 153

Query: 123 FF------KEAVFQYALYEPG-----LLEPEGVSKV--FFTCDSHEQLLPLEQAINARWG 169
            F      KE + Q  +   G     +   + + ++  +++ D   Q+ P  +A  A  G
Sbjct: 154 LFRLPGHHKEFMLQSRIPYEGSPRDFIAALDDIERLGSYWSEDMDAQVRPRVEAALAEVG 213

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
              +V+ S     E++A G SKG AL  + K LG S+    AFGD  ND EML+ AG G 
Sbjct: 214 -AFSVTSSMGVGAEILAKGTSKGTALLWLCKHLGLSVATAAAFGDADNDKEMLATAGIGV 272

Query: 230 IMGSAHQRL 238
            +G+ ++ +
Sbjct: 273 AIGNGNENV 281


>UniRef50_C0EYZ2 Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM
           3353 RepID=C0EYZ2_9FIRM
          Length = 268

 Score = 86.3 bits (212), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 66/267 (24%), Positives = 123/267 (46%), Gaps = 6/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V SD+DGTLL+ +H +S    E +  L  + I FV  + R    +  I +    +  
Sbjct: 4   YKAVFSDIDGTLLTSEHIVSTATIEAIASLQDKNIPFVIISSRSASCIYPILEKHHFQCP 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFMNRHRPEE 120
           ++   GA + D++G ++    + +  A+ +   + +   D+   +Y    W  N      
Sbjct: 64  IVACGGAWIEDMNGRILSNEGMSKQTAATVIEFMTEKKFDLAWGIYSGKNWITNDRTDAR 123

Query: 121 MRFFKEAVFQYALYEPGLLEPEG--VSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           +   +  V   ++     L PE   V+K+   C+    +L +E+ +   +   +++  S+
Sbjct: 124 ILHEESVVEVESVEGTVALLPEDAVVNKILCMCNP-ACILQIEEDLKKAF-PILSIVKSS 181

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LE+M  G++K   +    +    + +D +AFGD  ND EML  AG G +MG+A   +
Sbjct: 182 NYLLEIMPAGMNKAKGIRKFCELFSIATEDSVAFGDNYNDLEMLYAAGCGILMGNAPVAI 241

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
            +  P  +V   N  D +P  L+ L L
Sbjct: 242 LETFPG-KVTLDNNHDGIPVALKDLGL 267


>UniRef50_C6PUS4 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PUS4_9CLOT
          Length = 276

 Score = 86.3 bits (212), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 64/249 (25%), Positives = 117/249 (46%), Gaps = 13/249 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ASD+DGTLL+ D  +S Y    +   T+ G+ FV A+GR    +    + +     
Sbjct: 3   YKIIASDMDGTLLNDDKNISNYNLAMINKATSLGVKFVIASGRVPATLKFYEETIGKNQP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIIT-----NVYRDDEW----- 111
           +I +NGA V D + N+I+++ + +     +  ++ ++ D        NV+  +++     
Sbjct: 63  IICANGAIVLDHNKNIIYSNPISKSNLIKIINILREDKDTYYHFYDGNVFCSEQFEYSAK 122

Query: 112 -FMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            F N +R  + ++  E        +  +     + K+    D  + L  L   I+    +
Sbjct: 123 KFYNFNRKVDQKYRMEIRLIKDAKDYIIRSNSNIDKIVVMDDDVKYLEYLRCKIDNL--N 180

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            +  + S +  LE+M  G SKG AL+ +AK     ++ CIA G+  ND  M+  AG G  
Sbjct: 181 EIETTKSEINNLEIMGIGSSKGTALKLLAKYYEIPIEQCIAIGNDENDISMIKAAGVGIS 240

Query: 231 MGSAHQRLK 239
           M +    LK
Sbjct: 241 MANGRNSLK 249


>UniRef50_C2HD37 HAD superfamily hydrolase n=12 Tax=Enterococcus faecium
           RepID=C2HD37_ENTFC
          Length = 289

 Score = 85.9 bits (211), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 75/267 (28%), Positives = 127/267 (47%), Gaps = 31/267 (11%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASD+DGTLL    ++SP   E ++     G+ F+ ATGR++ +     D + I  
Sbjct: 1   MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGRNYQEARAALDEVGIDC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP---DIITN--VYRDDEW---- 111
            MIT NGA+V D +GN +F  ++  + A+ +  +++ N    ++ TN  +Y +++     
Sbjct: 61  AMITLNGAQVFDKEGNSLFTVSIPNNQATSVLDILDANGIYYEVATNDGLYSENQAKRIE 120

Query: 112 ----FMNRHRPEEMRFFKEAV-----------FQYALYEPGLLEPEGVSKVFFTCDSHEQ 156
                +  H P     +K A+             Y      +LE + +  +   C   E 
Sbjct: 121 SFASMVATHLPH--LTYKMAIAMASAKLELLHITYVDSIRTILEEKNLEVLKIICFHTEG 178

Query: 157 ---LLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFG 213
              L P+ + I +  GD + V+ S    +EV      KG A+  VA + G SL++ +  G
Sbjct: 179 PAVLGPVGKQI-SLLGD-LAVTSSGQNNIEVNHKNAQKGIAVAHVAHERGISLEEVMTIG 236

Query: 214 DGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           D  ND  ML +AG    MG+A   +KD
Sbjct: 237 DNFNDVSMLQVAGVSFAMGNAEIEVKD 263


>UniRef50_A6LQL6 Cof-like hydrolase n=1 Tax=Clostridium beijerinckii NCIMB 8052
           RepID=A6LQL6_CLOB8
          Length = 270

 Score = 85.5 bits (210), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 72/271 (26%), Positives = 131/271 (48%), Gaps = 14/271 (5%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETL-KLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           ++V  D+DGTLL+ +H ++   K T+ K+   + I  +  + R    +  +++ L I+  
Sbjct: 5   RMVCLDIDGTLLNSNHEVTEKVKSTINKVANNKKIPVILVSARMPKGIRFLQEELGIEEP 64

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR------ 115
           +I  +GA + D D +++    +D      ++ + ++N +I  ++Y+DDEW++ +      
Sbjct: 65  IICYSGALILDKDNSVLAREAIDVSNFEKIYKLTSEN-NIHMSLYKDDEWYIEKLDYWAK 123

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
              E        +    L E    E  G SK+    +  E +  L++ I   + + +N+ 
Sbjct: 124 QESEITNIIPNIIDFNKLIEQWKREGVGPSKILCMSNPKE-INFLKENI---YDNDLNIY 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S  T LE+M    SK  A+  + KK      + IA GD  ND +ML  AG G  MG+A 
Sbjct: 180 PSKPTYLEIMPIKASKTSAITCLQKKFSIDKSEIIAMGDNYNDIDMLEYAGVGVAMGNAP 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           + +K  H + +V  TN +D V   L K  ++
Sbjct: 240 EDVKK-HAD-DVTLTNDEDGVAEALIKYVIN 268


>UniRef50_C8P0W5 Phosphatase YidA n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414
           RepID=C8P0W5_ERYRH
          Length = 261

 Score = 85.5 bits (210), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 82/270 (30%), Positives = 126/270 (46%), Gaps = 20/270 (7%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR-HHVDVGQIRDNLEIK 59
           M +++A+D+DGTLL  DH L+P  +ET+  L  +GI F  ATGR     V  I D  E+ 
Sbjct: 1   MIKLIATDMDGTLLDADHALTPSMRETILKLRQKGIKFGVATGRPMDSAVFGIPDIAELF 60

Query: 60  SYMITSNGARVHDL-DGNLIFAHNLDRDIAS---DLFGVVNDNPDIIT---NVYRDDEWF 112
            + I  NG  V+D  DG +     L  D+     D F  +  NP ++T    +Y   E F
Sbjct: 61  DFAICDNGGFVYDFADGEIHEQFPLSGDLIREILDTFMPMGGNP-VLTGPGKLYTQFEDF 119

Query: 113 MNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
            N     E+R       +Y      +L+    +K+ F+ +  E L  +E  ++     R 
Sbjct: 120 YNI----EVR--THIDLEYVDVRSKVLDSH--AKIIFSGEP-ETLARIEAYVHENPDPRY 170

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
              +S    +E M   ++K   L+    K G ++ + + FGD  ND  M+  AG G  M 
Sbjct: 171 VAFYSQKELIEFMDPRINKMVGLQYYMDKYGITVDEIMTFGDNNNDLHMIEDAGHGVAME 230

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRK 262
           +A Q +KD+     V G N +D V  YL +
Sbjct: 231 NATQAVKDVAD--AVCGFNHEDGVKRYLDQ 258


>UniRef50_C7HV82 HAD phosphatase superfamily protein n=1 Tax=Anaerococcus vaginalis
           ATCC 51170 RepID=C7HV82_9FIRM
          Length = 278

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 72/274 (26%), Positives = 130/274 (47%), Gaps = 19/274 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTLL+    ++   K  L      G   V A+GR  + V    D LE + 
Sbjct: 8   MKKIIAVDIDGTLLNSKRQITEKTKNALIKAQELGHIVVIASGRDPLGVYPFADILEFEK 67

Query: 61  Y--MITS-NGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           Y  +I++ NG R+ +    ++I  H +D D+A ++      N  +   +Y +D+   +  
Sbjct: 68  YGGLISNFNGGRITNYKTKDVIINHPMDFDLAKEILQFSEKNLFMHYIIYTEDKIITSSS 127

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVS------KVFFTCDSHEQLLPLE-QAINARWG 169
           +  ++    E + Q A     +++    S      K+ F+ D +  L+  + + +  ++ 
Sbjct: 128 KTYKL----EEICQKAFTHYEVIDDLAYSLDFAPNKILFSQDPN--LIDDDAKKLMDKFS 181

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           ++     ST    E+M  G+ KG +L  +AK     +KD IAFGD  ND  M+ MAG G 
Sbjct: 182 NKTTQVKSTPYFYEIMPKGIGKGESLVEIAKYFDMDMKDVIAFGDEENDQTMIEMAGLGV 241

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           +M +    +K+      +  +N DD + +YL K 
Sbjct: 242 VMENGANFMKEKAD--FITKSNDDDGIAYYLEKF 273


>UniRef50_Q03FP9 Predicted hydrolase of the HAD superfamily n=28 Tax=Lactobacillales
           RepID=Q03FP9_PEDPA
          Length = 270

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 70/266 (26%), Positives = 115/266 (43%), Gaps = 11/266 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  DLDGT L+    LSP   +T+K  TA G      TGR +     I D L +K+ M
Sbjct: 4   KLITLDLDGTTLNSSSQLSPQTIKTIKNATAAGHIVSIVTGRPYRMARDIYDELSLKTPM 63

Query: 63  ITSNGARVH----DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
              NGA  H      DG   ++  +++ +  DL    +D    +  V   D +F +   P
Sbjct: 64  ANFNGALTHIPHQKWDGE--YSRTINKAVVYDLMKHKDDYGIQLLAVESKDSFFADHAAP 121

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF-- 176
               FF   +    +     L     S       +  Q   ++  +   +G+ + V    
Sbjct: 122 ASFEFFPHEISNDQILTEKTLRTNPTSITILVEPNSAQ--KVKNQLLHYYGEYITVGVWG 179

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
              + LE+++ G+ K  A+  +A       +D IAFGD  NDAEML   G+G  M +A  
Sbjct: 180 GPQSVLEIVSKGIQKAKAVAYLADYYHIDRRDTIAFGDEHNDAEMLDYVGRGVAMKNATD 239

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRK 262
           ++K +  ++     N +D V  YL +
Sbjct: 240 QIKGIANDITEFD-NTEDGVAKYLNE 264


>UniRef50_B8I4P5 Cof-like hydrolase n=2 Tax=Clostridium RepID=B8I4P5_CLOCE
          Length = 273

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 74/277 (26%), Positives = 124/277 (44%), Gaps = 17/277 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++VA DLDGTLL  +  +S   K  + +   +G+  V  +GR +         L I  
Sbjct: 1   MYRLVAIDLDGTLLDKNKEISERNKIAIHMAKEKGVKIVICSGRVYSGARIYAKQLGIMD 60

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +I  NGA + +  DG +I+++ +  D    +  + ++N  I  +VY  +     R    
Sbjct: 61  PIIACNGAIIRENADGKVIYSNYMHTDDCLKILDIFHENS-IYFHVYAGETMLTERLDYN 119

Query: 120 EMRFFKEAVFQYAL----------YEPGLLEPEG-VSKVFFTCDSHEQLLPLEQAINARW 168
            +++++     +A            E  L E +G V K+    D  E L  + + ++   
Sbjct: 120 SLKYYERNKALHAKDRVEIDIVTDMEKRLKELDGKVLKLVAVSDDSELLATVRKKLS--I 177

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
            + V+V+ S     EV+  GV+KG ALE ++  L    ++ IA GD  ND  M   AG G
Sbjct: 178 VETVDVTSSNYNNFEVVNKGVNKGKALERLSNMLKIPYREIIAIGDNENDIPMFDFAGLG 237

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             MG+     K+      +  TN +D V   + K  L
Sbjct: 238 VAMGNGEDCAKEAAD--YITATNTEDGVAKAIEKFIL 272


>UniRef50_A3DFI2 Cof-like hydrolase n=5 Tax=Clostridiales RepID=A3DFI2_CLOTH
          Length = 271

 Score = 85.1 bits (209), Expect = 2e-15,   Method: Compositional matrix adjust.
 Identities = 80/274 (29%), Positives = 131/274 (47%), Gaps = 22/274 (8%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  +  SDLDGTLL  D TLS +  +T+  LT +G+ F +AT R  V   ++   L    
Sbjct: 1   MKTLFVSDLDGTLLRSDETLSQFTIDTINGLTEKGMLFSYATARSLVTAKKVTKGLNSHI 60

Query: 61  YMITSNGARVHD-LDGNLIFAHNLD---RDIASDLF--GVVNDNPDIITNVYRDDEW-FM 113
            +I  NG  V D +   ++ A+  D    D+  DLF  G+    P + + +   +++ ++
Sbjct: 61  PVIVYNGTFVMDNVTEEILIANYFDDGIYDVFCDLFKEGIY---PIVYSYIDGIEKFSYI 117

Query: 114 NRHRPEEMR-FFKEAVFQYALYEPGLLEPEGVSKVFF-TC-DSHEQLLPLEQAINARWGD 170
                E M+ F           + G +E     K F+ TC D  E+L P  +    R+  
Sbjct: 118 PEKCTEGMKVFLNTRKGDKRTNKVGTIEELTAGKCFYITCIDEPEKLEPFSKKYKDRY-- 175

Query: 171 RVNVS---FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
           RV  S   +S    LE+M    SK +A+  + ++LG      ++FGDG ND +M  ++ +
Sbjct: 176 RVIYSKDVYSEFQWLEIMPKAASKANAILQLKERLG--CDRIVSFGDGENDIDMFRISDE 233

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLR 261
              + +A + LK +     +IG+N DD V  +LR
Sbjct: 234 AYAVDNAVESLKKVAT--GIIGSNNDDGVAKWLR 265


>UniRef50_B7GIG0 Predicted hydrolase of the HAD superfamily n=3 Tax=Bacillaceae
           RepID=B7GIG0_ANOFW
          Length = 288

 Score = 84.7 bits (208), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 67/266 (25%), Positives = 122/266 (45%), Gaps = 12/266 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ +DLDGTLL  D  +    +E +      GI+F  A+GR   ++ ++  ++   +
Sbjct: 22  MIRLIVTDLDGTLLGYDRRVKEEDREAVVRAITSGIDFAVASGRMDNEILEVLKDIGHDA 81

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           + I+ NGA V+  D  L+     DR +A  ++        I+  V  +   F+   + E+
Sbjct: 82  HRISQNGAFVYTSDHRLLHERTFDRALARSIYEQARALEAIVL-VCNEQTSFVET-KTEQ 139

Query: 121 MRFFKEAVFQYALYEPG-LLEPEGV----SKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           M   K  +F + + E G +L   G     SK+    + H  +   E+ +N  W   V+  
Sbjct: 140 MEQMKARLF-FDIVEKGDMLAAIGRDILPSKITVIGEEH-VVASFERFVNETWAPYVDTF 197

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S   CL++M   +SKG AL  +   L  + ++   FGD  ND  M  +     +M  A 
Sbjct: 198 ISEPRCLDIMPKQISKGEALRLLMSHLQLTAEEVACFGDSFNDIPMFRLTPHSFVMSHAP 257

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLR 261
           +++K    E   + ++  +A+   LR
Sbjct: 258 EQVK---KEARYVVSSVHEAIETVLR 280


>UniRef50_C4G5S2 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G5S2_ABIDE
          Length = 266

 Score = 84.7 bits (208), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 66/243 (27%), Positives = 116/243 (47%), Gaps = 11/243 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V SD+DGTLL+ +H +       ++ L  + I FV  + R    +  I +       +
Sbjct: 4   EIVFSDVDGTLLNNEHKMLEGTMYAIQKLQEKDIPFVIISARSPSGIYPILEENGFSCPI 63

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFM-NRHRP-- 118
           I  +GA + D   N +++   D++ A ++   + +   D   N+Y  D W + +++ P  
Sbjct: 64  ICYSGALILDDKKNTVYSTGFDKETAENVINFIEEEKFDCCWNLYSGDNWIVKDKNDPRV 123

Query: 119 --EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             EE     EAV       P   E   V K+   C+  E+ + +E  I  ++   ++V  
Sbjct: 124 ICEENIVHTEAVEGTLALLPDNAE---VGKILCICNP-EKTIEIEDKIKKQFP-MLSVVK 178

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S  T +E+M  G++KG A+  + K         +AFGD  NDA+ML + G   +MG+A +
Sbjct: 179 SFNTMIEIMQTGITKGSAVLELCKLWNIKPDKAVAFGDNFNDADMLDVVGFPFLMGNAPK 238

Query: 237 RLK 239
            LK
Sbjct: 239 ELK 241


>UniRef50_C0X6C9 HAD superfamily hydrolase n=22 Tax=Enterococcus faecalis
           RepID=C0X6C9_ENTFA
          Length = 277

 Score = 84.3 bits (207), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 74/281 (26%), Positives = 126/281 (44%), Gaps = 40/281 (14%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY- 61
           + +  D+DGTLL+ +  +SP  ++ L     +G++ + A+GR    +  + D LE+  Y 
Sbjct: 4   KAIVMDIDGTLLTSEKKISPKTRQALVAAQKQGLSLILASGRPTNGMRPLADELEMAHYN 63

Query: 62  --MITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             +++ NGA V H      +F   + + ++  +   +    D+I  +  +DE FM     
Sbjct: 64  GHLLSYNGACVTHHGSQQQLFNQTISKSLSQQILEHLKQF-DVIPMI--NDETFM----- 115

Query: 119 EEMRFFKEAVFQYALY-EPG---LLEPEGVSKVFFTCDSHE------------------- 155
                +   VF + L+ E G   ++E E     F  C+ H+                   
Sbjct: 116 -----YVNDVFHHTLHLETGDFNIIEYESRGGNFQLCEWHDLAARLNFPLNKILIAGEPA 170

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
            L    +AI A + + V  +FS     E  A  + K  +LE +  +LG + ++ IAFGDG
Sbjct: 171 YLQKYHEAIYAPFKETVTAAFSAPFYFEFTAKNIDKARSLEKLTLQLGIAAEEVIAFGDG 230

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAV 256
            ND  ML  AG G  M +A + LK +  E+ +   N   AV
Sbjct: 231 HNDYTMLEWAGTGIAMENAVEELKSIATEVTLSNDNDGIAV 271


>UniRef50_A3I4Q5 Cof-like hydrolase n=3 Tax=Bacillaceae RepID=A3I4Q5_9BACI
          Length = 256

 Score = 84.3 bits (207), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 69/245 (28%), Positives = 115/245 (46%), Gaps = 20/245 (8%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++  D+DGTL + +  L   AK  L      G     ATGR    +  + + L+I +
Sbjct: 1   MNKILFFDVDGTLYNSEKKLPESAKNALLEARHNGYELAIATGRAPFMIESLLEELDINT 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDL--FGVVNDNPDIITNVYRDDEWFMNRHRP 118
           Y +T NG  V    G +++ + ++++  + +  FG   + P     V+ DD+  +     
Sbjct: 61  Y-VTFNGQYVV-YKGEVVYTNGIEKEELAKIIAFGDARNEP----VVFLDDKRMIASVSD 114

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV-NVSF- 176
             M        +Y         PE  S  +   D ++ L+ +E+     + +   NV F 
Sbjct: 115 HMMVAESLDTLRYPY-------PELDSSYYMQNDVYQTLIFMEEKDEPLYCEMFPNVQFV 167

Query: 177 --STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
                +C +++  G SK   +E V  K+G +LKD IAFGDG+ND EML   G G  MG+ 
Sbjct: 168 RWHPYSC-DILPKGGSKAVGIEKVLDKMGITLKDAIAFGDGINDIEMLQAVGTGVAMGNG 226

Query: 235 HQRLK 239
           H+R+K
Sbjct: 227 HERVK 231


>UniRef50_Q03GV9 Predicted hydrolase of the HAD superfamily n=2 Tax=Lactobacillaceae
           RepID=Q03GV9_PEDPA
          Length = 290

 Score = 84.0 bits (206), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 74/287 (25%), Positives = 129/287 (44%), Gaps = 41/287 (14%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  ++ASD+DGTLL+ +  +S    + +K   A G++F  ATGR + +   + +   +  
Sbjct: 1   MISIIASDMDGTLLNEEMQISSANADAIKKAQAAGVHFAVATGREYREAKPLLEAYGLSV 60

Query: 61  YMITSNGARVHDLDGN------------LIFAHNLDRDIASDLFGVVNDNPDIITN---- 104
            +IT NGA V D+DG             ++  H L++   + L+  +  N  +++N    
Sbjct: 61  PLITLNGAAVFDVDGKALDMVPITKPSAVLIMHQLEK---AGLYYEITTNQGVVSNSRTR 117

Query: 105 ----------VYRDDEWF-----MNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFF 149
                         D  F     M+  R E M       +Q  + +P +   + +  V F
Sbjct: 118 RIQTVAHLLETVNPDTPFKLAVAMSSARVELMNIRYVDDYQVLIDDPKI---QVLKLVAF 174

Query: 150 TCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDC 209
             +  + L P+ +A++A+    ++ SF     +E+      KG A++  A +L   +   
Sbjct: 175 GENGQKGLQPVREALHAKVDVAISSSFE--NNIEINNPRAQKGIAVQHFADELNVPMSQV 232

Query: 210 IAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAV 256
           +  GD MNDA ML +AG    MG+A   +K L   L V  TN ++ V
Sbjct: 233 MTIGDNMNDASMLKIAGVSYAMGNAIPEIKKLANHLTV--TNNENGV 277


>UniRef50_Q8ELU0 Hypothetical conserved protein n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8ELU0_OCEIH
          Length = 294

 Score = 84.0 bits (206), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 79/286 (27%), Positives = 137/286 (47%), Gaps = 30/286 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIR-DNLEIKSY 61
           +++ASDLDGTLL  D T+S   ++ ++    +GI F+ ATGR + D  +I  +   I   
Sbjct: 2   KLIASDLDGTLLQEDGTISEANQKAIQAAIDKGIEFIVATGRSY-DAARIPLEKAGIDCS 60

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP---DIITN--VYRDD-EWF--- 112
           +I+ NGA  +  +  +I +  L++D+A  +  V +      ++ TN  +Y    E+F   
Sbjct: 61  VISLNGAVSYTKEKEIIRSIPLEKDVAKQITDVCDQEGMYIELFTNKGIYSGSREYFLEV 120

Query: 113 ----MNRHRP----EEMRFFKEAVFQYALYE-----PGLLEPEGVS--KVFFTCDSHEQL 157
               M    P    +++R   E  FQ+   E       +L+   ++  K+       EQL
Sbjct: 121 MVDIMTSANPNISEKDVREQAERRFQFEPVEFINDYHAVLDSTDINVYKILVFATEPEQL 180

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
               + + +  G  V ++ S    LE       KG A+E   ++  ++++D ++ GD  N
Sbjct: 181 SNASEKLRSEEG--VVITSSGEINLEFNHPEAQKGLAVEQYVQQKQWTMEDVMSIGDNWN 238

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           DA ML MAG+G  MG+A   +K L     +  TN +D V   L ++
Sbjct: 239 DASMLQMAGRGVAMGNAADEIKALCSYTTL--TNREDGVAVALEEM 282


>UniRef50_A8VVZ4 Ribonuclease H n=1 Tax=Bacillus selenitireducens MLS10
           RepID=A8VVZ4_9BACI
          Length = 245

 Score = 83.6 bits (205), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 63/237 (26%), Positives = 109/237 (45%), Gaps = 22/237 (9%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGT+L  DHT+ P     ++     G+  V +TGR  +      + L ++  +
Sbjct: 6   KLIALDIDGTILRNDHTIHPENITAIQKAVTNGLTVVLSTGRSLMACEHYAEQLGLRDLI 65

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           +T NG+ V  L   ++    L              NPD ++ ++        R+      
Sbjct: 66  VTGNGSEVWRLPDQVLHRVPL--------------NPDRVSYMWE----LKQRYDTYNWA 107

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
              E V++ A+  P  ++     K  F     E    + +A+ A   D + V+ S+ T +
Sbjct: 108 ATTEEVYKLAM--PERIDQHTWLKFGFDTKDDEARHAIIKALKA--CDDLEVTNSSETNI 163

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           EV A GV+K  ALE V+ + G ++ + IA GD +ND  M+   G G  MG+A +  K
Sbjct: 164 EVNAAGVNKAGALEIVSTETGIAMDEMIAMGDSLNDVSMIKACGIGVAMGNAQEITK 220


>UniRef50_A6LX51 Cof-like hydrolase n=3 Tax=Clostridium RepID=A6LX51_CLOB8
          Length = 289

 Score = 83.6 bits (205), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 67/277 (24%), Positives = 118/277 (42%), Gaps = 29/277 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A+D+DGTL+  +H +     E +K     GI F  ATGR + DV       +++ 
Sbjct: 1   MIKLIAADMDGTLIGKNHDIPKENIEAIKAAQKNGIKFAIATGRAYCDVEPFIHKYDLQC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             +  NGA   D++G+++    +++  A ++  V+    D+   +Y DD ++    + E 
Sbjct: 61  DCVVLNGAEYRDINGDIVEHTYIEKKRAIEILEVMK-CTDLAIEIYTDDGFYTTNTKEET 119

Query: 121 MRFF-------------KEAVFQYALYEPG-------------LLEPEGVSKVFFTCDSH 154
           +                +E + +YA   P              L     ++K      S 
Sbjct: 120 LAGMVKRSLTFHPELKDEEEILKYANNNPHFKNMQYITDMNEFLNRHNNIAKFVSFAQSE 179

Query: 155 EQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGD 214
           E +  L + + A  G  V+ SF   T +EV      KG  L  VA+KL     + +  GD
Sbjct: 180 EIINKLRKKMEALEGLAVSASFG--TNIEVNHMDAEKGKILAKVAQKLNIKKDEVVVLGD 237

Query: 215 GMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTN 251
           G+ND  M +       MG+A   +K++   +  I  N
Sbjct: 238 GLNDYSMFTEFQNSFAMGNAVDEIKEVAKYITDINVN 274


>UniRef50_C5RPZ1 Cof-like hydrolase n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RPZ1_CLOCL
          Length = 277

 Score = 83.6 bits (205), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 68/252 (26%), Positives = 115/252 (45%), Gaps = 23/252 (9%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V  D+DGTLLS  H + P   E +K  T  G+    ATGR         + L IK+ +
Sbjct: 4   KLVCIDMDGTLLSNHHEVHPKNLEAIKKATDLGVKIAIATGRIFASAKIYCELLGIKTPI 63

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE--- 119
           I++NG  +   D  ++  HN+  +    +  V+     +   +Y  D    N + PE   
Sbjct: 64  ISANGGYIRYGD-TVMAEHNMGYENCKKIVEVLEKFKSVYY-LYTADSMITNANIPETHP 121

Query: 120 ------------EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
                       +++F+       A+   G    + + K     +  E++  + Q IN  
Sbjct: 122 YRSMNDQLSDKDKLKFYHYDDISDAVENHG----DKIIKCIVMEEDFEEIQKIRQDINKI 177

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
            G  V  S++    +E+MA GV+KG   EA+AK  G+S  + +  GD  ND  M++ AG 
Sbjct: 178 QGLEVVSSYTN--NIEMMAAGVTKGKGAEALAKYYGFSRDEVMCIGDSENDLSMVTYAGF 235

Query: 228 GCIMGSAHQRLK 239
           G  MG+ ++ +K
Sbjct: 236 GVAMGNGNEAVK 247


>UniRef50_C6AQ91 Cof protein n=4 Tax=Bacteria RepID=C6AQ91_AGGAN
          Length = 390

 Score = 83.6 bits (205), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 69/264 (26%), Positives = 122/264 (46%), Gaps = 8/264 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V SD+DGTLL+  H ++P  +E +K +  RGI F+  + R    +    + L  +  
Sbjct: 132 YKAVFSDIDGTLLNSQHQITPKTEEAIKNILKRGIPFIPVSARPPYAITPYTEQLGSQHG 191

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           MI  +GA + D +   +++  L+      L  ++ D   +  + Y   +WF N    + +
Sbjct: 192 MICYSGALILDKNLTALYSVILEPQDLQKLNELLADFAHLSISYYAGLDWFCNDVNNDWI 251

Query: 122 RFFKEAV-FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           +   E       L +  L E   V K+     S E++  +E  +       +++  S   
Sbjct: 252 KQESEITGLSAELLQGNLTE---VHKI-LVMGSAEEIQTVEPVLKQAL-PHLSIHRSKDE 306

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE+     +K  A++ + + LG S +  IAFGD  ND +ML  AG    MG+A   +K 
Sbjct: 307 YLEITNPAATKAKAIQFMERHLGISAEQVIAFGDNFNDLDMLQYAGLSVAMGNAPDAIKQ 366

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
           +    EV  TN +D +   L +++
Sbjct: 367 VAK--EVTATNNEDGIALVLNRVF 388


>UniRef50_C4FY88 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FY88_9FIRM
          Length = 283

 Score = 83.2 bits (204), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 82/286 (28%), Positives = 132/286 (46%), Gaps = 31/286 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARG-INFVFATGRHHVDVGQIRDNLEIK 59
           M ++ ASD+DGTLL+P+H +S    + ++ L A+  I F+ ATGR +     + D  ++ 
Sbjct: 1   MIKLFASDMDGTLLNPNHVISDTTAQAIRDLQAQSDIEFLIATGRDYRSAKWLLDQHQLT 60

Query: 60  SYMITSNGARVHDLDGNL--IFAHNL-DRDIASDLFGVVNDNPDIIT---NVYRDDEWFM 113
           + +I  NGA  +D+ GNL  +FA +L D     + F V      +     N Y  ++  +
Sbjct: 61  ARIIAVNGAATYDVKGNLEDVFALDLADTQTIIERFAVPGTQTLVSLKSLNGYYVNDLAL 120

Query: 114 NRHRPEE-MRFFKEAVFQYAL---------------YEPGLLEPEGVSKVFFTCDSHEQL 157
            R R E  M   KEA    +L               Y+P L  P  +       D   ++
Sbjct: 121 YRQRMEAFMDHAKEATSDDSLAQLELHFKELLPLKDYQPDLDPPLKI----MLIDRRPEI 176

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
           L  E A +      ++++ S    LE+ +    KG A+EA  +  G++    +  GD  N
Sbjct: 177 L--ETARHFLKDFAIDLTSSGPDNLEITSLKAQKGLAIEAYCQHHGFTKHQVLTIGDSAN 234

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           D  ML+M      M +A Q +KDL    E   +NA+D V H + +L
Sbjct: 235 DRSMLAMFPNSYAMANAGQAIKDL-ASYEA-PSNAEDGVAHIIYQL 278


>UniRef50_Q3AFE4 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Carboxydothermus
           hydrogenoformans Z-2901 RepID=Q3AFE4_CARHZ
          Length = 266

 Score = 83.2 bits (204), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 74/271 (27%), Positives = 130/271 (47%), Gaps = 14/271 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLD T L+ +  +SP  ++ +     +GI    ATGR +    +   +      
Sbjct: 3   YRLLAVDLDDTFLNKELQVSPRVQQAVIEALKKGIIVTLATGRMYRSAKKYAFSFLGDIP 62

Query: 62  MITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NGA + +      ++   +  ++A  ++  V  +  +  NVY+DDE  +       
Sbjct: 63  LITYNGALIKYSRSEREVYHQPVPGELALTIYRRVKGHFHL--NVYQDDELLVEEDNQYI 120

Query: 121 MRFFKEAVFQYALYE--PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
             + K A   + +      LL  +  +K+    D  E+L  L +  N  +   ++++ S 
Sbjct: 121 RDYSKIAGVPFRVVSNIEELLGKKAPTKLLAIGDP-EELDQLWEETNGEFRGVLHITKSK 179

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LE +A GV+KG AL+ +A+ LG SL + +A GD  ND EML  AG G  MG+A   +
Sbjct: 180 PHYLEFLAAGVNKGEALKILAQHLGISLTETVAVGDSYNDLEMLEAAGLGVAMGNALPEV 239

Query: 239 K---DLHPELEVIGTNADDAVPHYLRKLYLS 266
           K   DL     V+  N +D + + + ++ L 
Sbjct: 240 KRRADL-----VVPANDEDGIAYLINEIILK 265


>UniRef50_C9LXL5 HAD-superfamily hydrolase, family protein IIB n=1 Tax=Selenomonas
           sputigena ATCC 35185 RepID=C9LXL5_9FIRM
          Length = 268

 Score = 83.2 bits (204), Expect = 8e-15,   Method: Compositional matrix adjust.
 Identities = 63/244 (25%), Positives = 110/244 (45%), Gaps = 25/244 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ +D+DGTLL   + +S   +  LK   A+G++   ATGR H+        + +   +
Sbjct: 4   RMIVTDMDGTLLDAKNGISEKNRAALKEAAAKGVHVAIATGRMHLSALPYAKEIGVTVPI 63

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ++ NGA V    G  +FA  +  D+  ++            +  ++  W++  +  E + 
Sbjct: 64  VSCNGALVKTTAGEELFASPIAPDVVREIL-----------DCMKEHGWYVQPYTDEGL- 111

Query: 123 FFKEAVFQYALYEP------------GLLE-PEGVSKVFFTCDSHEQLLPLEQAINARWG 169
           FF E   +   YE             GLL     V K+    D  E+       I+  + 
Sbjct: 112 FFCERDCRACAYEKLAGIEGKAVGWDGLLALGTRVFKLLSISDRAEETAVRAAEISRMFE 171

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
            +V    S    +++MA GVSK  ++E +A  LG ++ + +A GD  ND EML+ AG G 
Sbjct: 172 GKVRAVRSKEKYVDIMAEGVSKAASIERLAASLGINMSEVLALGDSDNDCEMLAAAGIGV 231

Query: 230 IMGS 233
            M +
Sbjct: 232 AMAT 235


>UniRef50_C6CY06 Cof-like hydrolase n=3 Tax=Paenibacillaceae RepID=C6CY06_PAESJ
          Length = 258

 Score = 83.2 bits (204), Expect = 9e-15,   Method: Compositional matrix adjust.
 Identities = 74/259 (28%), Positives = 118/259 (45%), Gaps = 21/259 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++   D+DGTLL  +  +     + ++ L A G+  V ATGR       I + L I SY
Sbjct: 3   YKIAFFDIDGTLLDEEKQIPQDTIDAIRDLQASGVPAVIATGRAPYFFAPIAEQLGIDSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            ++ NGA V    G  I+   + R+    L  V + +    T V+   + F         
Sbjct: 63  -VSLNGAYV-VYKGEAIYRRPIPREDVETL--VSHASAHNHTLVFEGHDSFYRNTESHPH 118

Query: 122 RFFKEAVFQYAL--YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN---ARWGDRVNVSF 176
            F   A  + A   ++P   + E V ++F  C + E+ L  E        RW D      
Sbjct: 119 VFNSVASLRVAQPGFDPDFWQKEDVYQIFLHCTAEEEHLYGEANPGLRFIRWHD------ 172

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
              T ++V+    SK   ++A+ K L  + ++ +AFGDG+ND EML + G G  MG++H 
Sbjct: 173 ---TAMDVLTIDGSKAQGIKALLKLLNIAPEEAVAFGDGLNDKEMLEVVGLGIAMGNSH- 228

Query: 237 RLKDLHPELEVIGTNADDA 255
             K+L P    I T+  D+
Sbjct: 229 --KELMPFANYITTHVSDS 245


>UniRef50_C8W906 Cof-like hydrolase n=5 Tax=Coriobacteriaceae RepID=C8W906_ATOPD
          Length = 265

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 70/270 (25%), Positives = 126/270 (46%), Gaps = 17/270 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASD+DGTLL  +  + P   E ++ L  RG++FV ++GR +  +  +   +  K 
Sbjct: 1   MIKLIASDMDGTLLDQNSEVPPETFELIEELHKRGVHFVASSGRRYDTLRWLFQPVADKI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASD-----LFGVVNDNPDIITNVY-RDDEWFMN 114
             + S G +V+      +    +DR++ S      LF + ++   I   VY R   + ++
Sbjct: 61  DYVASLGTQVY------VENEVIDREVFSSASIRALFELSSEFDCIHLVVYDRTHTYLLD 114

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPE-GVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
                     K+      +++P    P+  + K    CDS  + + +   +    GDR++
Sbjct: 115 DQSSFVRELDKDLPNAERVFDPP--SPDVSIIKAAVCCDSRARSMDMAMILEREMGDRLS 172

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              S  T ++V+  GV+K   LE + +  G S  +   FGD MND  ML  AG   +M +
Sbjct: 173 FMPSGETWIDVVPRGVNKATGLEQIRRYYGISRNEIAVFGDSMNDYAMLRYAGTAYVMDN 232

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           A   LK +    +VI  N +  V   +R++
Sbjct: 233 ARYALKTIA--TKVIAPNTEQGVQKEMRRI 260


>UniRef50_A9B0P7 Cof-like hydrolase n=1 Tax=Herpetosiphon aurantiacus ATCC 23779
           RepID=A9B0P7_HERA2
          Length = 271

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 71/240 (29%), Positives = 112/240 (46%), Gaps = 12/240 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLDGTLL      S   +  +    A G++   ATGR         D L+I + 
Sbjct: 5   YRLLALDLDGTLLDSRLEPSAATRAAIADAQAAGVHVTIATGRMIRTAQPFADMLQITTP 64

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +IT  GA V   DG +++ + L  D+A+++  +      +    Y DDE ++    PE  
Sbjct: 65  LITYQGAHVQTADGTVLYDNPLPADLAAEVVELALAE-GLYIQAYIDDELWIVERSPEVE 123

Query: 122 RFFKEAVFQYAL-YEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAIN---ARWGDRVNV 174
            +   ++    +   P L+E    + V+K+ +  D  E    LE+ ++    RW  R+ +
Sbjct: 124 EYLGFSLVDIPVNIAPNLVEIVRQKPVTKLVWITDPTE----LERTMHEWGERWKGRLEI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S     E  A G SKG  L  +A+ L     +  A GD  NDA ML+ AG G  MG+A
Sbjct: 180 FRSHDHFGEAAAIGSSKGVGLAVLAEHLDIPQAEVAAIGDRENDASMLAWAGFGMAMGNA 239


>UniRef50_Q71XA3 HAD-superfamily hydrolase, subfamily IIB n=19 Tax=Listeria
           RepID=Q71XA3_LISMF
          Length = 270

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 74/273 (27%), Positives = 125/273 (45%), Gaps = 23/273 (8%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  DLDGT L  D T+S + K+TL+     G   + ATGR +   G     L + + +
Sbjct: 4   KLIVLDLDGTTLRDDLTISSHTKKTLEKARMAGHEVMIATGRPYRISGSYYHELGLTTPI 63

Query: 63  ITSNGARVHDLDGNLI---FAHNLDRDIASDLFGVVND-NPDIITNVYRDDEWFMNRHR- 117
           +  NGA  H          + H +D  +  +L    N  + D I    +D+ +   R+  
Sbjct: 64  VNFNGAVYHHPRLTTFAEGYHHAIDLQVVHELLDFSNGFSLDNIAAEVQDNVFLKERNNS 123

Query: 118 -PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLP--LEQAINA-----RWG 169
            PE      E +    + +   ++ +  S +FF       L+   L+++++       WG
Sbjct: 124 VPETFHLGTENIVFGNIRDA--IKSDATSLLFFGKIDQLDLISKHLDESLSGVISHHTWG 181

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
                  S    +E++  G+ K   ++A AK LG+  KD IAFGD  ND +ML  AG G 
Sbjct: 182 A------SAWPAVEIIKFGIHKAIGVQAAAKTLGFDRKDIIAFGDETNDLQMLDYAGVGV 235

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRK 262
            MG+A + +K++     V  +N DD +  YL +
Sbjct: 236 AMGNAAESVKNVAN--VVTASNQDDGIALYLEE 266


>UniRef50_A5UZ29 Cof-like hydrolase n=2 Tax=Roseiflexus RepID=A5UZ29_ROSS1
          Length = 271

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 69/240 (28%), Positives = 115/240 (47%), Gaps = 9/240 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           +++++A DLDGT++  D  + P  +ET+  + ARGI+   ATGR           L+I++
Sbjct: 2   LFRLIALDLDGTVIDRDLVIHPDVRETIAAVQARGIHVTLATGRMFNAAMPFARELDIRA 61

Query: 61  YMITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +I   GA V H L G  ++ H       +        + DI    Y  D  ++  HR E
Sbjct: 62  PIICYQGALVRHPLTGETLY-HATMPADLAAAAVHALLDADIFVIAYIHDVHYIAAHRSE 120

Query: 120 EMRFF----KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQA-INARWGDRVNV 174
              +     +E     A     L+     +K+ F  +   Q++  E A ++ R+G+ + +
Sbjct: 121 LEAYLAFHPEENEIVVAPDLERLVARMAPTKLLFVAEP--QVVERELARLSDRFGEALAI 178

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S     E+ A  VSKG AL  +A+ LG + ++ +A GD  ND  M++ AG G  MG+A
Sbjct: 179 IRSHAIFGELTAPHVSKGQALATLAESLGVAREEVMAIGDQENDLSMITWAGLGLAMGNA 238


>UniRef50_C9LXL4 HAD hydrolase, IIB family n=1 Tax=Selenomonas sputigena ATCC 35185
           RepID=C9LXL4_9FIRM
          Length = 265

 Score = 82.8 bits (203), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 66/247 (26%), Positives = 113/247 (45%), Gaps = 7/247 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  DLDGTLL+ +  +S Y+K+ L+    +G+    ATGR  +        +   + +
Sbjct: 4   RLIVMDLDGTLLTSEKMVSDYSKDVLRRAMEKGVAVTLATGRMLLSASYFGRIIGANAPI 63

Query: 63  ITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           I+ NGA V  LD    +F      +  ++L     +N       Y  D+ +    RPE  
Sbjct: 64  ISCNGALVQALDATEPLFLRAFSPETVAELLTFAREN-GWYAQWYIGDDIYAEDFRPEYF 122

Query: 122 RFFKEAVFQYALYEPGL-LEP--EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
             ++  V  +A++E G    P  EGV++V    D    +  +  +I  R+  RV+   S 
Sbjct: 123 TAYR-TVQGFAVHEVGEDFSPYVEGVAQVVVR-DLAGGVGAIAASIRERFAGRVDPQQSK 180

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              L+++  GVSK   +EA+ +  G    + +A GD  ND  ML +AG   +  +  +  
Sbjct: 181 GYTLDLVPTGVSKATGIEAILRATGIRADEVMACGDSDNDLSMLRLAGTSVVTANGQEEA 240

Query: 239 KDLHPEL 245
           K L   L
Sbjct: 241 KALATYL 247


>UniRef50_C4IB07 Cof protein n=1 Tax=Clostridium butyricum E4 str. BoNT E BL5262
           RepID=C4IB07_CLOBU
          Length = 266

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 58/266 (21%), Positives = 125/266 (46%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           ++++ SD+DGTLL+  H +S   KE+L LL    I FV  + R    + +++  + + S 
Sbjct: 4   FKIIFSDIDGTLLNSSHEVSEKNKESLVLLNKLNIPFVLVSARMPQGIKKVQKEINVNSP 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDN-PDIITNVYRDDEWFMNRHRPEE 120
           ++  +G  V D +G  + +  +  + A ++   ++    ++ T+ Y  D+W  +  + E 
Sbjct: 64  IVCYSGGLVIDSNGKYLMSIGIRIEKAQEIKNYIDGKWKNVSTSYYSYDKWIADNKKDEW 123

Query: 121 MRFFKEAVFQYALYEP--GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           +    +      ++     + E   V          + +  ++ +I+ ++ + +++  S 
Sbjct: 124 IAQESDITSVNPIFGKIQDICEKNSVVHKILCMGDSKVIDEIKDSISEKY-EGLSIYKSK 182

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
            T LE+M    +K  A++ +       ++D I+ GD  ND +M+  AG G  M +A   +
Sbjct: 183 DTYLEIMELDATKSGAMKVLCDSFNIKMEDTISIGDNYNDVDMIKAAGNGIAMANAPDEV 242

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           K +  EL    +N +D V   + K +
Sbjct: 243 KRISNEL--TSSNDNDGVAEVIYKYF 266


>UniRef50_A4EA96 Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens
           ATCC 25986 RepID=A4EA96_9ACTN
          Length = 264

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 72/278 (25%), Positives = 127/278 (45%), Gaps = 28/278 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M++++ASD+DGTLL  +  + P   E +  L   G++F  ++GR +  + +    +  K 
Sbjct: 1   MFKLIASDMDGTLLDENGQVPPETYELILALHEHGVHFAASSGRRYDRLCEFFAPVRDKM 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIAS-----DLFGVVNDNPDIITNVYRDDEWFMNR 115
             + +NGA+V+  DG ++     DR++ S      L   V   P++   ++   + F+  
Sbjct: 61  DFVAANGAQVY-ADGKMV-----DREVYSHLAIRRLAQAVRTFPNLHLALFDRTKSFL-- 112

Query: 116 HRPEEMRFFKE-------AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARW 168
              +E +F +E       A   + L +P +     + K    CD    ++     +    
Sbjct: 113 -LDDECKFVREVDKDLPNAERIWELPDPSV----NIIKASIFCDD-SAVMDSAYVLQREL 166

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
           G     + S    ++ M  GVSK   +  +A+  G    + +AFGD MND E++   G G
Sbjct: 167 GQLFTFAPSGNAWIDAMQPGVSKASGIAQLAEHYGIGRDEVMAFGDSMNDYEIIRFVGTG 226

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           C M +A   LK +     V+G N D AV   LR++  S
Sbjct: 227 CAMENARPALKAVAD--RVVGCNRDHAVQQELRRVLES 262


>UniRef50_C1D022 Putative uncharacterized protein n=2 Tax=Deinococcus
           RepID=C1D022_DEIDV
          Length = 281

 Score = 82.4 bits (202), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 76/242 (31%), Positives = 109/242 (45%), Gaps = 27/242 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A+DLDGTLL  D ++SP  + TL    A G++ V  T R    V +I +      + 
Sbjct: 4   RLIATDLDGTLLRRDLSVSPRTRRTLDCARAAGLHVVPVTARQPRGVRRIAEAAGFNGWA 63

Query: 63  ITSNGAR-VHDLDGNLIFAHNLDRDIASD------------LFGVVNDNPDIIT--NVYR 107
           +  NGA  VH   G ++F  ++ +D+               LF  V +  ++      Y 
Sbjct: 64  LCGNGAHGVHLHTGEVLFEAHVQQDVQRAVAQALLVQVPEVLFVSVRNGGEVFVAQEGYA 123

Query: 108 DDEWFMNRHR-PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINA 166
           D   F +  R P EM  F     Q  L +P L        V     S  +LL   QA+  
Sbjct: 124 DLAHFEDHKRDPAEMGTFS---LQDVLEQPSL-----KFIVRHPSLSPRELLAHVQALKL 175

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
                  V+ S    LEV+A GVSK   LE +   LG    + +AFGD  NDAEML+ AG
Sbjct: 176 ---PGFAVTHSGAPFLEVLAEGVSKAWGLERLCAHLGVRRDEVLAFGDAPNDAEMLAWAG 232

Query: 227 KG 228
           +G
Sbjct: 233 RG 234


>UniRef50_C2DYX9 HAD superfamily hydrolase n=8 Tax=Lactobacillus jensenii
           RepID=C2DYX9_9LACO
          Length = 262

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 62/243 (25%), Positives = 113/243 (46%), Gaps = 4/243 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ SD+DGTL++    + P  KE++     +G  FV  + R  + +  +   L IK  +
Sbjct: 2   RIIFSDIDGTLINDKLEILPRTKESILKEVKKGNLFVPVSARSPLAMQTVIKQLGIKCPL 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
              NGA + + +G  I++  L    A ++   +ND   I  N+Y    W   + + + + 
Sbjct: 62  SAFNGALILNEEGVQIYSKPLPLAEAREIVKELNDLTSITWNIYSGLSWLTQKPKTQAL- 120

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKV--FFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             +E + +       + E E +  +           L  L +  + R+ +   V  S  T
Sbjct: 121 LAEEKIVKLRAKAIDISEIENLKCIHKVLVMGPKNILDELLKTYSQRYNNLYLVK-SKDT 179

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE++A GV K  +++ V+      + + +AFGD  ND  ML   GKG +MG+A + LK 
Sbjct: 180 LLEIVASGVEKADSIKRVSDYYHVEISNTLAFGDNYNDEGMLKTVGKGYLMGNAPEELKK 239

Query: 241 LHP 243
            +P
Sbjct: 240 HYP 242


>UniRef50_C4FT61 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FT61_9FIRM
          Length = 269

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 74/277 (26%), Positives = 122/277 (44%), Gaps = 24/277 (8%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A DLDGTLL+    +S   ++ L    ++G+  V  TGR +  +     +L +  
Sbjct: 1   MIKLIAIDLDGTLLNAQKEVSQANRQALAYAKSKGVKVVLCTGRPYFAMKHFLADLGLVD 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFG--VVNDNPDIITNVYRDDEWFMN 114
            + Y++T NG  V    DG ++ ++ L     SD+     V  N D+  NV   D  +  
Sbjct: 61  PEDYIVTFNGGMVQKAQDGQVLVSNTLG---TSDVLAWYQVTQNLDLPINVIDADRLYEP 117

Query: 115 RHRP--------EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINA 166
              P        E +      V  Y  ++P     +     F    + E L      ++ 
Sbjct: 118 TAYPVGYPSLYLENVTNVPSVVQDYKTFDP-----DHAFNKFVIVTTQEHLDAQIPKLDP 172

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
            + D+  V  S    LEVM  GVSKG  L  + + L  S ++ +  GD  ND  M+ +AG
Sbjct: 173 DFKDQYAVFKSRSFFLEVMKKGVSKGDTLAKLGELLDISPQEMMTMGDQENDLSMIELAG 232

Query: 227 KGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            G  MG+A +++K     + +  TN +D V H + K 
Sbjct: 233 LGVAMGNATEQVKASAQYVSL--TNEEDGVAHAIHKF 267


>UniRef50_C2KAT0 Possible sugar-phosphatase n=1 Tax=Chryseobacterium gleum ATCC
           35910 RepID=C2KAT0_9FLAO
          Length = 266

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 72/257 (28%), Positives = 112/257 (43%), Gaps = 37/257 (14%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ +D+DGT L+  H +SP   E  K L  R I FV A+GR    +      +E +   
Sbjct: 5   KLIVTDMDGTFLNSSHEMSPEFSEVYKELKKRNIVFVPASGRQMPGITHYFGEIESEIGF 64

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP---------DIITNVYRDDEW-- 111
           I  NG  V   D  L FA  L+     D+   V + P          +      D ++  
Sbjct: 65  IAENGGYVIYKDQEL-FADTLEYKYIVDIIKAVREIPGAKAVLSAKKMAYYETEDQQFVD 123

Query: 112 FMNRHRPEEMRF------FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN 165
           F +++  E M+         +  F+ A+Y P     EG  K  +      +   LE  ++
Sbjct: 124 FFSKYYTENMKKDDLTEKIDDTAFKIAVYHP-----EGSEKHLYPALKKFEEFGLEIVVS 178

Query: 166 -ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSM 224
            A W             L+VM   ++KG+AL+ + K LG S ++ +AFGD MND EML  
Sbjct: 179 GAHW-------------LDVMNKDINKGNALKILQKSLGISPENTMAFGDYMNDIEMLKN 225

Query: 225 AGKGCIMGSAHQRLKDL 241
           A     M +AH  +K +
Sbjct: 226 AKYSYAMQNAHPNVKQV 242


>UniRef50_C2LPY8 HAD-superfamily hydrolase, subfamily IIB n=5 Tax=Streptococcus
           RepID=C2LPY8_STRSL
          Length = 269

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 72/250 (28%), Positives = 114/250 (45%), Gaps = 21/250 (8%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ SD+DGT+L+ +H +     E +  L    I FV A+ R  + +  I   L +    
Sbjct: 5   RLIISDIDGTILTSNHQVEEQLIEVMPELEKANIPFVLASARSPLGMQPIAHKLGLHDNP 64

Query: 63  ITS-NGARVHDLDGN-LIFAHNLDRDIASDLFGVVN-DNPDIITNVYRDDEWFMNR---- 115
           I   NGA V  L+G+  I  H +D+    DL   ++ D P +  N+Y   +W  N     
Sbjct: 65  IACYNGALV--LEGDRTIIQHPVDKAEIQDLLNYLSKDYPSVSVNIYSGKDWITNELDKW 122

Query: 116 -----HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
                    E    KE     +  EP + +   + +     D H++LL ++    A +  
Sbjct: 123 SQLEGSITGESPIIKELQDTVSDSEPPIHKLLLIDEPEVIQDLHQKLLSMDFPQTAFYLS 182

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           + N        LEV A  VSK HAL  VAK     L+  +  GD  ND+ ML++AG G  
Sbjct: 183 KDN-------YLEVTAKHVSKEHALLEVAKYYDLPLEQVMTIGDNFNDSPMLALAGLGIA 235

Query: 231 MGSAHQRLKD 240
           MG+A + +K+
Sbjct: 236 MGNAPEGVKE 245


>UniRef50_C1P783 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36D1
           RepID=C1P783_BACCO
          Length = 305

 Score = 82.0 bits (201), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 72/273 (26%), Positives = 122/273 (44%), Gaps = 41/273 (15%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + +ASD+DGTLL+    +SP   E +KL   +GI+FV  TGR + +   + D + I  
Sbjct: 18  MIECIASDMDGTLLNSRQEVSPANAEAIKLAQKKGIHFVVTTGRSYEEARLVLDPVGIDC 77

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVN--------------------DNPD 100
            +I  NGA V D  G L+    LD   AS +  V +                    +N D
Sbjct: 78  TVIGLNGAEVRDEKGKLLKTSGLDPLTASQVADVFDQLGIYYEFFTNKGTYTEDYEENMD 137

Query: 101 IITNVYRDDEWFMNRHRP-EEMRFFKE--AVFQYA---------LYEPGLLEPEGVSKVF 148
           ++ N++       N   P EE+R + E   + +Y           ++P +L      K+ 
Sbjct: 138 MLVNLFHT----ANPEVPVEEVRNYIEQRGIRRYVHNIRDTKDIFHDPSIL----FYKIL 189

Query: 149 FTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKD 208
              +  ++L  + + +   + D + V+ S    +E+      KG AL+   +K G S++ 
Sbjct: 190 AFNEDEQRLRQIGKHLEKDFPD-IKVTSSGFRNIEINHVSAQKGIALKEYTEKHGLSMEK 248

Query: 209 CIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
            +A GD +ND  ML   G    MG+A   + ++
Sbjct: 249 TMAIGDNLNDISMLERVGYPFAMGNAENEVLEI 281


>UniRef50_B0NZ00 Putative uncharacterized protein n=1 Tax=Clostridium sp. SS2/1
           RepID=B0NZ00_9CLOT
          Length = 275

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 75/276 (27%), Positives = 125/276 (45%), Gaps = 18/276 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++V +DLDGTLL+    +S    + ++ L  + I FV ATGR  V        L+   
Sbjct: 1   MYRMVVTDLDGTLLNNKKQVSEANVKAIQNLKDQNITFVMATGRSDVMTRAYTKQLKNVD 60

Query: 61  YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +I  +GA + ++  G ++  ++L  +     F +      +   V+  DE   +   P+
Sbjct: 61  IVIGCDGAVIRNIRTGEILCENHLRSETCHTTFEICK-KYGLQYYVFAKDELVSDD--PQ 117

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSK----------VFFTCDSHEQLLPLEQAINA-RW 168
             RF     F   + E   + P  ++           ++    SH     L++     + 
Sbjct: 118 NERFLVHQKFNQTVEEDEEI-PMQIADDLNEYVNDHIIYKIVVSHNDTSYLDKVAEVIKK 176

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
               +   S    L V A GVSK  A++ +A+KLG  +KD IAFGD +ND EML++ G G
Sbjct: 177 ETDADAIRSGKKVLAVKARGVSKAEAIKKLAQKLGILIKDIIAFGDEVNDIEMLTLVGLG 236

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             M +A   +K+     ++ G N  D V   L K++
Sbjct: 237 IAMENADDVVKEAAD--QIAGRNDQDGVGKELEKIF 270


>UniRef50_C4L8T6 Cof-like hydrolase n=1 Tax=Tolumonas auensis DSM 9187
           RepID=C4L8T6_TOLAT
          Length = 273

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 79/283 (27%), Positives = 124/283 (43%), Gaps = 36/283 (12%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           V+A D+DGTLL+ DHT++    +TL+    +GI  +  TGRHH+    +   L +++ +I
Sbjct: 6   VIALDMDGTLLTSDHTVTRETVDTLRQARDKGIEVILVTGRHHMMACPVHHQLALETPLI 65

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIA-SDLFGVVND-NPDIITNVYRDDEWFMNRHRPEEM 121
            SNGA + D     I A N   D     L  ++     D+I + + D       H+P+ +
Sbjct: 66  CSNGAYIFDFQAKRITAGNPLHDWQWQQLLPLIESLQLDVICH-FSDGI----GHQPDNV 120

Query: 122 RFFKEAVFQYAL---YEPGLLEPEGVSKVFFTCDSHEQLLPLE------QAINARW---- 168
              K       L   + P  +E   ++ +   C++H  L  +E       AI+A      
Sbjct: 121 HIAKIKNHLSTLPPEHYPHFIEHSSLATL---CNTHVPLWKIEIAHATPAAIDAFIDALP 177

Query: 169 -GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
            G  +    +    LE++  G SKG+ L       G +L   IAFGD  ND  M    G 
Sbjct: 178 DGLAITHDRTAPNGLEIVNTGSSKGNRLAEWVAGKGIALDQVIAFGDNHNDISMFQQVGL 237

Query: 228 GCIMGSAHQRLKDLHPELE-----VIGTNADDAVPHYLRKLYL 265
           G  MG+A        PE++     V  +N D  +   LR+  L
Sbjct: 238 GVAMGNA-------TPEIQQYADFVTCSNDDSGIASALRRWVL 273


>UniRef50_C8RSV0 HAD family hydrolase n=2 Tax=Corynebacterium jeikeium
           RepID=C8RSV0_CORJE
          Length = 272

 Score = 81.6 bits (200), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 74/282 (26%), Positives = 126/282 (44%), Gaps = 37/282 (13%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +V SD+DGTLL+    +S   +  +  +  +G  F  ATGR    +  + + L ++    
Sbjct: 7   LVVSDVDGTLLNSRERVSQRMRRAVSSMLRQGTVFTIATGRPPRWLMPVFEQLPVRPVCA 66

Query: 64  TSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDN-PDIITNVYR-------------- 107
            +NGA ++D D + ++ A  L+ D+   L   ++++ P +   V R              
Sbjct: 67  CANGAIIYDADRDQIVHAATLEPDLIRALIEQLSESVPGVGFAVERAGTSAFDRADELFS 126

Query: 108 -----DDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQ 162
                D  W    H  + +    E +    + +  + +P   S   F       + P   
Sbjct: 127 VSPGYDHAWDSTEHAVQSL----EELAAKPVVKLLVRDPNRTSAELFAA-----VRPFID 177

Query: 163 AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
           A  A+       S+     +EV A G+SK  ALE +A+++G      IAFGD  ND EML
Sbjct: 178 ATQAK----ATYSYEG-GLVEVSAAGISKRSALEWIAEQVGVDAAQTIAFGDMPNDTEML 232

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           + AG G  MG+A + LK++  E+ +  TN +D V   L + +
Sbjct: 233 TWAGHGVAMGNAEESLKEVADEVTL--TNDEDGVAAVLERWF 272


>UniRef50_P0A8Y6 Phosphatase yidA n=235 Tax=cellular organisms RepID=YIDA_ECOL6
          Length = 270

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 82/288 (28%), Positives = 126/288 (43%), Gaps = 45/288 (15%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS-- 60
           +++A D+DGTLL PDHT+SP  K  +    ARG+N V  TGR +  V      L ++   
Sbjct: 4   KLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTGRPYAGVHNYLKELHMEQPG 63

Query: 61  -YMITSNGARVHD-LDGNLI-----------FAHNLDRDIAS-----DLFGVVNDNPDII 102
            Y IT NGA V    DG+ +           F   L R++ S     D   +   N DI 
Sbjct: 64  DYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSREVGSHFHALDRTTLYTANRDI- 122

Query: 103 TNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQ 162
            + Y   E F+             A       E   ++P   +  F      ++   L+Q
Sbjct: 123 -SYYTVHESFV-------------ATIPLVFCEAEKMDP---NTQFLKVMMIDEPAILDQ 165

Query: 163 AINARWGDRVNVSFSTLTC----LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
           AI AR    V   ++ L      LE++   V+KG  ++++A  LG   ++ +A GD  ND
Sbjct: 166 AI-ARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAIGDQEND 224

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             M+  AG G  M +A   +K++     V  +N +D V   + K  L+
Sbjct: 225 IAMIEYAGVGVAMDNAIPSVKEVAN--FVTKSNLEDGVAFAIEKYVLN 270


>UniRef50_UPI000196B980 hypothetical protein CATMIT_00184 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196B980
          Length = 544

 Score = 81.6 bits (200), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 59/251 (23%), Positives = 114/251 (45%), Gaps = 11/251 (4%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A D+DGTLL  D T+SP    +L     +G +    TGR   ++      L+   Y I
Sbjct: 278 LLALDMDGTLLKSDKTISPNTAASLIEANKKGQSICLCTGRGLAELKDYEGELDFCDYGI 337

Query: 64  TSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
             +G  ++D   +  +  H+ D D+ + +  +V    D++  +        ++   E M 
Sbjct: 338 LLSGCLIYDFKNDQPLEVHSFDTDVFTQMMDIVK-KEDVMLYLLDSSHSIASQKDVENMP 396

Query: 123 FFKEAVFQYALYEPGLLEPEGV--------SKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
           ++  A++Q +++E      E +         ++   C  +  +  + Q +       V+ 
Sbjct: 397 YYNMAIYQ-SMFESRAFVVEDIYEYAEVHKDEILKFCLYNPSVDAMNQLLKKLEVFPVSC 455

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           +    T +EV   G++KG  LE+++  L   +++ I  GD  ND E    AGK   MG+A
Sbjct: 456 AVVEETAIEVTPLGITKGAGLESLSSYLNIPIENTIMMGDSGNDIEAFQSAGKAVAMGNA 515

Query: 235 HQRLKDLHPEL 245
            + +K+L  E+
Sbjct: 516 TEEIKNLATEI 526


>UniRef50_B0P090 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P090_9CLOT
          Length = 298

 Score = 81.3 bits (199), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 70/273 (25%), Positives = 126/273 (46%), Gaps = 17/273 (6%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VA DLD TLL  +  +S + +E LK    RG+  V ATGR    + +   ++    Y 
Sbjct: 27  KLVAMDLDNTLLDSEKQISKHTEEVLKEAIRRGVYIVPATGRIFKAIPEFLRDIPGVRYA 86

Query: 63  ITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +  NGA V+D   N +I+ ++L ++    LF ++ +      ++Y++ + +M R   + +
Sbjct: 87  VCCNGATVYDQKENKIIYTNHLPKETVFSLFDIL-EKYHCTRDIYQNGQGYMERCYFDHL 145

Query: 122 RFFKEAVFQYALYEPGLL-----------EPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
             +  +     L     L            P G+ K+    D  E+     Q +  +  +
Sbjct: 146 AEYGVSDHVLKLVRDTRLPLDDLRKYIEERPLGIEKINVFFDDMEERETARQELIEK--N 203

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
             +VS S    +E+   G  KG  L  +A+++G S+ + +A GD  ND  M+   G G +
Sbjct: 204 IASVSSSLGNNIEINQIGCDKGDGLLHLAEQIGLSMDEVMACGDAGNDTMMIKAVGTGVV 263

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           M +    LK++     V  TN +D V + + KL
Sbjct: 264 MENGQPDLKEIAD--FVTKTNNEDGVAYAIEKL 294


>UniRef50_Q03YR8 Predicted hydrolase of the HAD superfamily n=3 Tax=Leuconostoc
           RepID=Q03YR8_LEUMM
          Length = 277

 Score = 81.3 bits (199), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 65/237 (27%), Positives = 113/237 (47%), Gaps = 13/237 (5%)

Query: 38  FVFATGRHHVDV-GQIRD---NLEIKSYMITSNGARVHDL--DG--NLIFAHNLDRDIAS 89
           FV  TGR +  V G ++D   N + K Y+++ NG  + ++  DG   +I  H +D ++A 
Sbjct: 38  FVPNTGRSYKSVFGTLKDLGLNKQNKQYVVSYNGGAIVEIHEDGGEKIIVQHGMDLELAK 97

Query: 90  DLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLE----PEGVS 145
            +F +     DI T++Y  D  F+      + ++ +E    Y       L+     + + 
Sbjct: 98  KIFSLGQIQADIDTHIYTIDTLFIYNISKNDEQYMRERSVPYQEMANDKLDFLSNEKTIM 157

Query: 146 KVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYS 205
           KV F     + L  +   +NA+  DRV  +FS+   +E    G  KG A   +A  LG S
Sbjct: 158 KVIFEHRDPDVLQKIADTVNAQLADRVLTTFSSNRYVEFNPKGSDKGSAGLELADMLGIS 217

Query: 206 LKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRK 262
             +  A GD +NDA  +  AG G  + +A   +K++  +L +  TN + AV  ++ +
Sbjct: 218 RNEVAALGDNLNDAAQIKAAGVGVAVANAKPEIKEM-ADLVLSKTNNEGAVAEFINE 273


>UniRef50_C0C6F9 Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM
           15053 RepID=C0C6F9_9CLOT
          Length = 275

 Score = 80.9 bits (198), Expect = 4e-14,   Method: Compositional matrix adjust.
 Identities = 75/255 (29%), Positives = 122/255 (47%), Gaps = 27/255 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL----EI 58
           ++VA DLDGTLL+ +   +  A + +   + RGI  + ATGR    +G I + +     I
Sbjct: 6   KMVAFDLDGTLLTTEKVFTERAGKAITKASERGIVLLPATGRP---LGAIPEEILHYPGI 62

Query: 59  KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
           + Y IT+NG RV D + GN+I+   +  +IA  +  +  ++ D +  VY D   F     
Sbjct: 63  R-YAITANGGRVVDTVSGNVIYEKPVPPEIARKVLDIY-EHYDTLREVYYDGAGFAEEKM 120

Query: 118 PEEMR-FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR----- 171
              +R FF   V     Y      P  V+ +    +S  + +   QA+ A   D+     
Sbjct: 121 LRRIRDFF--GVSAMGDYILSTRTP--VADIREKFESEGRAVDKVQAVFASLADKQKALE 176

Query: 172 -------VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSM 224
                  + V+ + +  +EV   GV+KG+AL A+ + L    ++ +A GDG ND EML  
Sbjct: 177 ELSEIEGIEVTGALVNNIEVSVQGVNKGNALLALGEMLHIKKEEILALGDGANDIEMLKK 236

Query: 225 AGKGCIMGSAHQRLK 239
           AG G  M ++   +K
Sbjct: 237 AGIGIAMANSSDEVK 251


>UniRef50_A6LS28 Cof-like hydrolase n=4 Tax=Bacteria RepID=A6LS28_CLOB8
          Length = 275

 Score = 80.9 bits (198), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 71/252 (28%), Positives = 120/252 (47%), Gaps = 20/252 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTAR-GINFVFATGRHHVDVGQIRDNLEI-- 58
           Y+++A D+D TLL+ +H +     + +K      G+ FV ATGR +     I+++L+I  
Sbjct: 3   YKLIACDMDETLLNDNHIICQRNIDLIKRAKKEYGVKFVPATGRGY---SSIQNDLKILD 59

Query: 59  -----KSYMITSNG-ARVHDLDGNLIFAHNLDRDIASDLF--GVVNDNPDIITNVYRDDE 110
                  Y+I+ NG A   + D  L+    L  D   ++F  G+   N D+  +VY  D+
Sbjct: 60  LYDQAGEYIISFNGGALTENKDNKLLQFKGLRFDKMKEIFEYGL---NKDVCIHVYTKDK 116

Query: 111 WFMNRHRPEEMRFFKEAVFQYALYEPG---LLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
            ++      E    K    +  + +     LLE E ++K+ +   +   L+ +E  + + 
Sbjct: 117 LYIYNLSQSEKERIKNQKLECTIMKENTVDLLEEEPIAKIIYQNINVPYLMGIEPDMRSI 176

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
                 VS+S+   +E  + GV KG  L  +AK L   +KD IA GD  ND  ML +AG 
Sbjct: 177 TEGHCAVSYSSNRYMEFNSLGVDKGSGLINLAKILDIDIKDTIAVGDNYNDMSMLKVAGL 236

Query: 228 GCIMGSAHQRLK 239
               G+A + +K
Sbjct: 237 SVASGNAVEDVK 248


>UniRef50_B1MW64 Predicted hydrolase of the HAD superfamily n=4 Tax=Leuconostoc
           RepID=B1MW64_LEUCK
          Length = 273

 Score = 80.9 bits (198), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 67/239 (28%), Positives = 113/239 (47%), Gaps = 15/239 (6%)

Query: 3   QVVASDLDGTLLSPDHTL-SPYAKETLKLLTARGINFVFATGRHHVDVGQI-RDNLEIKS 60
           Q++A+DLDGT L+ D T      K  L+ L A+ I FV ATG H   +  +  D L    
Sbjct: 5   QLIATDLDGTFLADDKTFDKALFKVVLERLKAKNIGFVIATGVHQERIEMLLADFLHAGL 64

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASD---LFGVVNDNPDIITNVYRDDEWFMNRH- 116
           + +T+NGARV   +G +++   +   + +    L       PD       DD  ++ R  
Sbjct: 65  FYVTNNGARVIAPNGEVLYNQAIPWSVLAQIQTLITAFEPKPDQGLVYSTDDTAYIPRSF 124

Query: 117 ----RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
                 + +++FK+ +    + E  ++    V+  +   D  +     +QA+    G +V
Sbjct: 125 SHLATDDRLKYFKKVILFDDVSEI-VMPIFKVTMNWIDFDESKLYAAAKQAL----GHQV 179

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           +V+ +    ++++  GV+K   L+ +A  LG  L    AFGDG ND EML+  G   IM
Sbjct: 180 HVTETGTGAIDIVPAGVNKAVGLKVLADNLGIQLSQVAAFGDGGNDIEMLTQVGYPYIM 238


>UniRef50_A7VIL5 Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50
           RepID=A7VIL5_9CLOT
          Length = 272

 Score = 80.5 bits (197), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 82/281 (29%), Positives = 133/281 (47%), Gaps = 28/281 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V SDLD T+L  D  +S   KE L+ L    + F+ A+GR    + +    +    Y
Sbjct: 3   YRCVVSDLDRTILRRD-GISHRTKEVLEKLADSHVIFIPASGRSVYSIPECIREIRGIRY 61

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF-------- 112
            ITSNGA ++DL D + ++   L  ++   +F +V D  D+    + D   +        
Sbjct: 62  AITSNGAAIYDLSDDHSVYNLKLRPEVPEQIFDLVTDK-DVFFECFIDGRGYTSEIYYEN 120

Query: 113 -MNRHRPEEMRFFKEA-------VFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAI 164
            MN    E++  +  +       + Q+ L      E + +S V  T   +  +  L Q I
Sbjct: 121 PMNFGESEDISAYVRSTRTPVPDIRQFILQHN--TELDSISIVGPTEKKYRIMHELTQNI 178

Query: 165 NARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSM 224
           +      V V+      +E+      K + L+ V + LG S+++ IAFGDG ND+EML+ 
Sbjct: 179 HT-----VYVTSGAPRLIEISDRHSGKHNGLKEVLRFLGISMEETIAFGDGDNDSEMLAE 233

Query: 225 AGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           AG G  + +A +R K+   +L VIG   DD+V  +L K  L
Sbjct: 234 AGLGVAVLNATERCKEA-ADL-VIGDYLDDSVADFLEKTVL 272


>UniRef50_D2RIN9 Cof-like hydrolase n=2 Tax=Acidaminococcus RepID=D2RIN9_ACIFE
          Length = 269

 Score = 80.5 bits (197), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 68/247 (27%), Positives = 108/247 (43%), Gaps = 20/247 (8%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLL  +  ++P     +K   A G     ATGR +         L +   +
Sbjct: 4   KMIAMDLDGTLLDEEKNIAPEDAAAVKDAVAAGYYVTLATGRMYRSALPYAQELRLTHPL 63

Query: 63  ITSNGARVHDLD-----GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
           +  NGA + D       G      ++ + +  DL G       I    Y DD  +  R  
Sbjct: 64  VVYNGALIRDPGTGENLGQWPLPLDVAQSVLDDLLGW-----GIYVQAYVDDTLWAPRD- 117

Query: 118 PEEMRFFKEAVFQYALYEPGLLE----PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            EE+RF+    F    YE         P+   K+    D    L P    +  ++  ++ 
Sbjct: 118 CEEVRFYSR--FSRVPYEVKTEAIRHLPQAPHKLLVISDQVRTLRP---ELEEKYRGKIK 172

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +  S+   LEV A G +K HAL+A+A + G   ++ +  GD  ND EM+S AG G  MG+
Sbjct: 173 IVSSSKGFLEVTAPGTNKWHALQALAAREGIREEEILCVGDSDNDLEMISHAGFGVAMGN 232

Query: 234 AHQRLKD 240
           A   +++
Sbjct: 233 ASDPVRE 239


>UniRef50_C9BZM0 HAD-superfamily hydrolase n=12 Tax=Enterococcus faecium
           RepID=C9BZM0_ENTFC
          Length = 269

 Score = 80.5 bits (197), Expect = 5e-14,   Method: Compositional matrix adjust.
 Identities = 73/273 (26%), Positives = 130/273 (47%), Gaps = 16/273 (5%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++ A DLDGTLL  +  +     + L+     G     ATGR+ +    I   L I  Y+
Sbjct: 2   KLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRNSISAKDIFSELGIGGYL 61

Query: 63  ITSNGARVHDL-DGNL---IFAHNLDRDIASDLFGVVNDN--PDIITNVYRDDEW-FMNR 115
           I+SNG+ + ++ DG +   +    +D D     F    +     I +   +DD+  F   
Sbjct: 62  ISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAKISIIASRETQDDQLTFDES 121

Query: 116 HRPEEMRFFKEAVFQYALYEP--GLLEPEGVS--KVFFTCDSHEQLLPLEQAINARWGDR 171
           +  ++  +++    Q   ++    +LE   +S  K+  T  S E+L  L++ + A   D 
Sbjct: 122 NLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALTDKSEEKLQKLQRDLQA---DG 178

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           +   FS    LE+   G++K H+L  +A  LG    D +AFGD  ND  ML+ +G    M
Sbjct: 179 IQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMAFGDQENDIAMLNYSGLSIAM 238

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G+A +++K++  ++ +  TN +  V + L+  Y
Sbjct: 239 GNAQRQVKEIANQVTL--TNEEAGVAYILKNFY 269


>UniRef50_Q5FQA0 Putative hydrolase of the HAD superfamily n=1 Tax=Gluconobacter
           oxydans RepID=Q5FQA0_GLUOX
          Length = 266

 Score = 80.5 bits (197), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 64/248 (25%), Positives = 109/248 (43%), Gaps = 24/248 (9%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +V SD+DGTLL+PD T++P     +++L  RGI    A+ R    +    + L +     
Sbjct: 1   MVVSDMDGTLLTPDKTIAPSTLAMVRVLQERGIPLCLASARPPAAMVPYIEQLGLTGQNA 60

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRF 123
             NG  +   DG      ++ R ++ D+  +V+D    + +++  + WF+     +    
Sbjct: 61  GFNGGIIFKPDGTT----SVSRVLSPDVLSIVHD----MLHLHGIETWFLR----QSYWM 108

Query: 124 FKEAVFQYALYEPGL--LEP----------EGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
            ++A   +  +E G+  L P          EG+ KV         L  +E  + A     
Sbjct: 109 VQDAYTPFVQHEQGITGLTPHQVPDLRKEFEGIGKVMGVSSDTSLLQDVETELGAMLQGD 168

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
            +V  S+   L+V     +KG A+  +A  LG +  +    GD  ND  M S+AG G  M
Sbjct: 169 ASVRRSSDILLDVTPALANKGEAVRELALALGIAPHEVACLGDAHNDLPMFSVAGLGIAM 228

Query: 232 GSAHQRLK 239
           G A   +K
Sbjct: 229 GQAEDDVK 236


>UniRef50_C4XFJ4 Putative uncharacterized protein n=1 Tax=Mycoplasma fermentans PG18
           RepID=C4XFJ4_MYCFE
          Length = 285

 Score = 80.5 bits (197), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 75/286 (26%), Positives = 125/286 (43%), Gaps = 47/286 (16%)

Query: 8   DLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR-HHVDVGQIRDNLEIKSYMITSN 66
           DLDGTL   +  +    K TLK L     N + ATGR ++++   I+D L+IK  +I  N
Sbjct: 16  DLDGTLYDDNKNILESTKNTLKQLQKENKNIIIATGRPYYMNYKLIKD-LDIKLPIIAVN 74

Query: 67  GARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNP-DIIT--------NVYRDDEWFMNRH 116
           GA ++D +   + +   LD+ +  +L   + +N  D +         N + +  WF    
Sbjct: 75  GAMIYDPITKEVPYFQGLDKKVVQELINFLEENRIDFLAYDINGMKGNNFSNPYWF---- 130

Query: 117 RPEEMRFFKEAV----FQYALYEPGLLEPEGVSKVFFTCDSHE--------QLLPLEQ-- 162
              E   +K  V    +++   E  L E         TC+           Q +P E+  
Sbjct: 131 ---EFMIYKNVVETNPYRWDYQEGSLKE---------TCNQFNFAKILIITQNVPQEKID 178

Query: 163 ---AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDA 219
               I +++  ++    S    +++M  G+SKG  L+ +AK     L   +AFGD  ND 
Sbjct: 179 SLLTIASKFPKQIYTVSSQKGVIDIMPIGISKGETLKKIAKIKNIDLSKAMAFGDADNDI 238

Query: 220 EMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            ML        MG+A + LK +     V  TN +D +   +++L L
Sbjct: 239 SMLKSVKISVAMGNATENLKKVAT--YVTDTNNNDGIAKIIKELEL 282


>UniRef50_B4CZE7 Cof-like hydrolase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4CZE7_9BACT
          Length = 267

 Score = 80.5 bits (197), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 67/241 (27%), Positives = 102/241 (42%), Gaps = 22/241 (9%)

Query: 8   DLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNG 67
           DLDGTLL PD  +S      ++ L   G   V A+GRHH  + +    +    ++I+S G
Sbjct: 9   DLDGTLLGPDKQISAENLRAVERLREAGFETVIASGRHHRSIMRFEQEIGPMGWVISSAG 68

Query: 68  ARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEA 127
           A V     N +       +  +           ++T  Y  D  FM            EA
Sbjct: 69  AVVRHAVTNELLHELTIPEAEALAVHAAARRAGLVTLAYHRDGVFMEATE-------NEA 121

Query: 128 VFQYAL---YEP-----GLLEPEGVSKVFFTCDSH---EQLLPLEQAINARWGDRVNVSF 176
           V+ YA    ++P       +   G+ K+  +       E  L LE+A      DR+ V +
Sbjct: 122 VYAYARRAGWKPKRADLAHMAASGIQKLLISESPEILAEAGLVLERAFT----DRLYVVW 177

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           +    +E ++   +K    EA+A+KLG   +D  +FGD  ND EML+ AG    MG    
Sbjct: 178 TEKDIVEFLSPQANKAVGTEALARKLGIEQQDVWSFGDSNNDVEMLAWAGFSVAMGHGQP 237

Query: 237 R 237
           R
Sbjct: 238 R 238


>UniRef50_C5RM50 Cof-like hydrolase n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RM50_CLOCL
          Length = 259

 Score = 80.5 bits (197), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 73/277 (26%), Positives = 124/277 (44%), Gaps = 38/277 (13%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRH-HVDVGQIRDNLEIK 59
           M+ V+A DLDGTLL  D T+S    E LK     G   V  T R   ++V ++   L+ +
Sbjct: 1   MFDVIALDLDGTLLKNDKTVSEKTIEALKKCEELGKQIVIVTARSPRLEVIRLPAELQ-R 59

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +MI  NGA+++  +   I+  N+  D A  +        D+I   Y   +     +   
Sbjct: 60  EFMIFYNGAKIYQ-NNKRIYIQNISLDSAESI-------KDLILRKYAQCKVGFEINNKL 111

Query: 120 EMRFFKEAVFQYALYEP---GLLEPEGVSKVFFTCDSHEQL------LPLEQAI----NA 166
              F  +++F    +E       + E  +KV     + + +      LPL+  +    N 
Sbjct: 112 YTNFKNDSIFGTTKFETIDLNTFKLEAPTKVLIDMSNIQDINDFKLYLPLDCNLIITDNG 171

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
           + G             ++MA GV+K ++L  + K L  S+   + FGD +ND E++   G
Sbjct: 172 KLG-------------QIMAQGVNKLNSLRYILKGLDTSIDRVMFFGDDVNDIELIKECG 218

Query: 227 KGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            G  MG+A +++KD+     V  TN +D +  +L K 
Sbjct: 219 IGVAMGNAIEKVKDIAK--YVTTTNEEDGIAVFLDKF 253


>UniRef50_B0P1S7 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P1S7_9CLOT
          Length = 270

 Score = 80.1 bits (196), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 77/270 (28%), Positives = 118/270 (43%), Gaps = 14/270 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLDGTL +    ++      +      GI    A+GR    +   RD L++  +
Sbjct: 3   YKLIAVDLDGTLYNDQLKITSDTLNAMIEAQEMGIRIALASGRPLPGLFHARDLLKLNEH 62

Query: 62  ---MITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              ++  NG +V D   N +++   +  D+A +L   + D P    N   DD   +    
Sbjct: 63  HGMLVAYNGGKVVDTTTNEVLYDKYIQDDLAMELLEHLKDYP---VNPIIDDGKVLYVTD 119

Query: 118 PEEMRFFKEAVFQYALYE--PGLLEPEG--VSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
               R  +EA+     Y   P L E     ++K+    D  +    LE  I   + D+V 
Sbjct: 120 KNGYRVKEEALNDSMEYVEVPSLTEHLDFHLNKILTAVDPQKTYDVLE-TIGMPFRDQVT 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              +    +E +  G SK   L  V K LG    + IAFGD  ND EM+  AG G  MG+
Sbjct: 179 FVRTAPYYIEAIPVGTSKASGLSNVCKGLGIDPSEVIAFGDAENDLEMIQFAGHGVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           A   LKD   E+ +  TN +D + H L  L
Sbjct: 239 ACDALKDAADEVTL--TNNEDGIAHTLNHL 266


>UniRef50_Q38VQ4 Putative hydrolase, haloacid dehalogenase family n=1
           Tax=Lactobacillus sakei subsp. sakei 23K
           RepID=Q38VQ4_LACSS
          Length = 262

 Score = 80.1 bits (196), Expect = 8e-14,   Method: Compositional matrix adjust.
 Identities = 66/239 (27%), Positives = 106/239 (44%), Gaps = 15/239 (6%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ASD+D TLL+    L P  ++ +K LTA+GI F  A+GR    + Q+  NLE    +
Sbjct: 4   KLIASDMDHTLLNESGQLPPNFEQVVKQLTAKGIIFTAASGRPLYTLKQMFANLENDMCL 63

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           +  NG  V    G++IF   L       +   VN+    I  +   D  ++         
Sbjct: 64  VGDNGG-VISYQGDIIFKSLLPLTDYQRMVAFVNEGQTGIGMICGMDAVYIEEQYQALDA 122

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLP-------LEQAINARWGDRVNVS 175
            F++  +    Y P L      +KV    D      P        EQ     +G   +V+
Sbjct: 123 TFRQ-FYAEIKYVPDL------TKVSVEADKFTVYFPEANSRDFYEQIYGPTFGADYSVA 175

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
            + +  +++M  G+ KGHA+  +A     S  + +AFGD  ND EML       +MG+A
Sbjct: 176 VAGVEWVDIMNKGIDKGHAMRFLANHFNISTDEMMAFGDTYNDKEMLQTVKYSYLMGNA 234


>UniRef50_C6PVB1 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PVB1_9CLOT
          Length = 270

 Score = 79.7 bits (195), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 62/237 (26%), Positives = 116/237 (48%), Gaps = 6/237 (2%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++ SD+DGTLL+ +  +S    E +    A+G  F FATGR      +  D + +   +I
Sbjct: 9   LLISDMDGTLLNSNKKISKNNIEAINRFVAQGGIFTFATGRMLESAKKYLDVVNVNVPVI 68

Query: 64  TSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVY-RDDEWFMNRHRPEEM 121
             NG+++HD      I+   L+ ++ + L  +      +   +Y +++ +  N+ R  + 
Sbjct: 69  LYNGSKIHDYGKKETIYELFLEDEVKNILKQIKQQYSYLGLEIYCKENVYIFNKCRFSKR 128

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
                +   Y +  P  L  E  +K+    + + QL  LE    +++G + N+  S    
Sbjct: 129 FASNRSDVHYDI--PESLWTENWTKILILGEEN-QLDILEHNFISKFG-QFNIVRSGENY 184

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
           LE++  G SKG AL+ + K +   + + IA GD MND E+L  +G G  + + +++L
Sbjct: 185 LEILPLGTSKGQALQKLCKIINIDISNTIAVGDNMNDFELLKKSGYGFCVANGNKKL 241


>UniRef50_A7HK89 Cof-like hydrolase n=1 Tax=Fervidobacterium nodosum Rt17-B1
           RepID=A7HK89_FERNB
          Length = 270

 Score = 79.7 bits (195), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 69/246 (28%), Positives = 114/246 (46%), Gaps = 24/246 (9%)

Query: 8   DLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL--EIKSYMITS 65
           DLDGT+L+P +      KE +  +  +G N VFATGR H+   ++ D +  E    +I+ 
Sbjct: 11  DLDGTVLTPKNEFPLETKELIMNILKKGDNVVFATGRMHISAKKLLDRVFGEDVFPIISY 70

Query: 66  NGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFK 125
           NGA V+  D   IF   L+   A  +      N +I    Y +D  +  +   E   + K
Sbjct: 71  NGAVVYVPDKGFIFEKTLELSTAHKVIDFFRRN-NIHVQTYVEDILYTEKDNEEIKLYSK 129

Query: 126 EAVFQY-------ALYEPGLLEPEGVSKVFFTCDSH--EQLLP-LEQAINARWGDRVNVS 175
            A   Y       A+++P +       K+    D    ++L+P L+  +    G+   V 
Sbjct: 130 HAEVPYTVVDDLKAIHQPPI-------KILGIGDQELLDRLIPDLKNVV----GNSATVF 178

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    L+V+    +KG AL  +A  L + L + I FGD  ND  M  +AG+   + +A 
Sbjct: 179 KSFSIFLDVVPADANKGIALRFLADYLKFDLSETIVFGDNENDIFMFEVAGRKIAVSNAV 238

Query: 236 QRLKDL 241
           ++LK++
Sbjct: 239 EKLKEV 244


>UniRef50_A4F639 Cof protein n=1 Tax=Saccharopolyspora erythraea NRRL 2338
           RepID=A4F639_SACEN
          Length = 270

 Score = 79.7 bits (195), Expect = 9e-14,   Method: Compositional matrix adjust.
 Identities = 80/282 (28%), Positives = 118/282 (41%), Gaps = 38/282 (13%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +VASD+DGTLL     +S     T++ + A  + FV  TGR    +  +   L +    +
Sbjct: 6   LVASDVDGTLLDSMERVSSRTAATVRRVVADDVPFVLVTGRPPRWMPSVVAGLGVSGVAV 65

Query: 64  TSNGARVHDLDGNLIFAHN-LD----RDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            +NGA ++D   + + A   +D     D+  +L    ++ P     V R      +R   
Sbjct: 66  CANGAVLYDTKADAVLASTEIDTVTLHDVVHELH---HEMPGCAVAVERTTGGAHDR--- 119

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSH------EQLLPLEQAINARW---- 168
                    V +  L E G L+    S +              +LL L  A+N+      
Sbjct: 120 ---------VHEQFLAEEGFLQVWANSDIHVAAPDELVGKPAVKLLVLHDAMNSAQMAAI 170

Query: 169 -----GDRVNVSFST-LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
                GDR+ +++ST    +E  A GV K   L  VA  LG    D IAFGD  ND  ML
Sbjct: 171 AEEVVGDRLEMTYSTGAGIIEFSAAGVDKASGLRTVAADLGVDQADVIAFGDMPNDVPML 230

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           S  G G  M +AH+    L    EV  TN D+ V   L + +
Sbjct: 231 SWVGHGVAMRNAHE--AALAVADEVTATNNDNGVAQVLERWW 270


>UniRef50_A8HYJ4 Haloacid dehalogenase-like hydrolase n=1 Tax=Chlamydomonas
           reinhardtii RepID=A8HYJ4_CHLRE
          Length = 323

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 71/268 (26%), Positives = 118/268 (44%), Gaps = 8/268 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVD-VGQIRDNLEIKSY 61
           +++ +D+DGTLL     LSP  +  +K   A G+  V ATG+        +   L++ + 
Sbjct: 43  RLIVTDVDGTLLDSSQQLSPRVEAAVKEARAHGVPLVIATGKARGPWTADVLLGLQLDTP 102

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH--RPE 119
            +   G  V+D  G ++    L  D+A D   +  D   +    Y  D           +
Sbjct: 103 GVFMQGLIVYDDQGRVLHERRLCEDVARDCITLAADV-GVTLTAYCGDRILCAATDVHTD 161

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVS--KVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
            + F+KE   +        L   GV   K+ F  D  +++  L  A  A    R +++ +
Sbjct: 162 RLLFYKEPPPEPVGDLAAALGGGGVPVHKMIFMAD-QDRIDALRPAAEALLDGRASLTTA 220

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LEV+  G SKG  L  +   LG + +  +A GDG ND EML +AG G  MG+A  +
Sbjct: 221 LTGMLEVLPLGGSKGAGLSWLLDWLGVAPEQVLALGDGENDVEMLQLAGLGVAMGNAGPK 280

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +    ++ +  TN  D V   +++  L
Sbjct: 281 AR-AAADVVLAATNDQDGVAEAIQRFVL 307


>UniRef50_D1D7N6 Predicted protein n=10 Tax=Proteobacteria RepID=D1D7N6_NEIGO
          Length = 114

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 36/92 (39%), Positives = 63/92 (68%), Gaps = 1/92 (1%)

Query: 2  YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
          ++ + SDL GTLL+P+H +     +TL++L  +G++ + ATGR+H D+  I   +   ++
Sbjct: 5  FRAMVSDLGGTLLTPEHLVGDLTIDTLRVLEQKGVDIILATGRNHTDMSSILGKIGAERA 64

Query: 61 YMITSNGARVHDLDGNLIFAHNLDRDIASDLF 92
           MITSNGARV DL GNL+++++L  ++  +L+
Sbjct: 65 VMITSNGARVRDLQGNLLYSNSLPEELVLELY 96


>UniRef50_B9CKY2 Phosphatase YidA n=1 Tax=Atopobium rimae ATCC 49626
           RepID=B9CKY2_9ACTN
          Length = 273

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 77/277 (27%), Positives = 118/277 (42%), Gaps = 19/277 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL----E 57
           Y+++ASDLD TLL  +H L    +E +     +G+ FV A+GR++  +      L    +
Sbjct: 4   YKLIASDLDETLLDSEHCLPKNVREAVLAARKKGVKFVPASGRNYQSIQVTLRELGLYDQ 63

Query: 58  IKSYMITSN-GARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDE-WFMNR 115
              Y I+ N G    + D ++I    +  + A+++        D+  +VY   + W  N 
Sbjct: 64  PDEYTISFNSGIITENKDNHIISMEGISHEFANEILQRALTLGDLCVHVYTAHKIWAWNV 123

Query: 116 HRPEEMRFFKEAVFQY-ALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGD-- 170
             PE  RF+   + +     EP L  L  E + K          L      + A W D  
Sbjct: 124 --PEIERFYTSKLQKMDETTEPNLAFLAGEKIIKCLVMNTDAAYL----HRLAAEWQDIT 177

Query: 171 -RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
             ++VSFS    LE    G++KG  L  +   L    KD IA GD  ND  M+  AG G 
Sbjct: 178 EDIDVSFSANRYLEFNKKGINKGTGLVRLGHILNIPTKDIIAIGDNYNDLPMIKTAGLGV 237

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            M +  + LK     +  +  NA   V   + K  LS
Sbjct: 238 FMANTPEELKSQADYVTTLDNNA-GGVAEVIEKFVLS 273


>UniRef50_UPI00018506A2 hypothetical protein Bcoam_01805 n=1 Tax=Bacillus coahuilensis m4-4
           RepID=UPI00018506A2
          Length = 289

 Score = 79.3 bits (194), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 74/290 (25%), Positives = 126/290 (43%), Gaps = 30/290 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + +A+D+DGTLL+ +  +S   K  ++    +G+  V ATGR + +   +     +  
Sbjct: 1   MVKCIATDMDGTLLNHEQRISERNKLAIETAIQQGVKVVVATGRSYPEAATVLKEANLSL 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIAS---------DLF-------GVVNDNPDIITN 104
            +I  NGA + +  G ++++  + ++ AS         D++       G  ++N  +  +
Sbjct: 61  PIICVNGAEIRNTAGEVVYSKGMKKERASFIAKELKKRDIYFEIYTNKGSFSENYQLGVD 120

Query: 105 VYRDDEWFMNRHRPEEMRFFKEAVFQYAL--------YEPGLLEPEGVSKVFFTCDSHEQ 156
           V  D     N   PEE+   K AV +  +        YE      E     F      ++
Sbjct: 121 VIVDIFHTANPEIPEEL-IRKRAVERLEVGVFEEISDYETIFSSSEYDVYKFLVFSKQKE 179

Query: 157 LLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGM 216
           +L     +     D + +S S    LE+ +    KG AL     + G SL+D +A GD +
Sbjct: 180 VLKEAYEVLVEIED-IAISSSGEENLEINSSDAQKGIALSHFVAEQGISLEDTLALGDNL 238

Query: 217 NDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIG-TNADDAVPHYLRKLYL 265
           ND  MLS+ G    MG+AH   KD+    E    TN +D V   +  + L
Sbjct: 239 NDVSMLSVVGYPVAMGNAH---KDVLALCEYTTLTNREDGVGRAIESIVL 285


>UniRef50_B5CTA9 Putative uncharacterized protein n=4 Tax=Clostridiales
           RepID=B5CTA9_9FIRM
          Length = 279

 Score = 79.0 bits (193), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 63/253 (24%), Positives = 112/253 (44%), Gaps = 21/253 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           YQV+  DLDGTL +    ++   ++ L  +   G   V A+GR    V  +   L ++  
Sbjct: 11  YQVIVLDLDGTLTNSKKEITEPTRQALIDIQKNGKTVVLASGRPINGVAPLAKQLRLQDF 70

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVN----DNPDIITNVYRDDEWFM 113
             YM++ NGARV    DG +I+   +  ++   +  +V        D+IT     D   +
Sbjct: 71  GGYMLSFNGARVTRCSDGKIIYNKQIPPEMIRPICDIVRSYAEQGVDLITYT---DTTII 127

Query: 114 NRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDS------HEQLLPLEQAINAR 167
           +   P +    +  + +  +Y+P     + VS + F  +        + L  L + +  +
Sbjct: 128 SAIAPNQYTRIESGINRMEIYQPD----DFVSYIDFPINKLLVPGPADVLQELMKLLKEK 183

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
           +   +N+  S    LE+M   + K H+L+ +   +G +    I  GDG ND  M+  AG 
Sbjct: 184 YHGLLNIYLSEPYFLEIMPQNIDKAHSLQKLLNSIGLTADSMICCGDGFNDLSMIEYAGL 243

Query: 228 GCIMGSAHQRLKD 240
           G  M +A   +KD
Sbjct: 244 GVAMENAQPIIKD 256


>UniRef50_A8VQS9 Type III restriction enzyme, res subunit n=1 Tax=Bacillus
           selenitireducens MLS10 RepID=A8VQS9_9BACI
          Length = 262

 Score = 79.0 bits (193), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 13/235 (5%)

Query: 8   DLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNG 67
           D+DGTLL+PD+ +S   K+ +  L  +G+    ATGR           L + + MI  NG
Sbjct: 9   DMDGTLLNPDNRISGRNKDAVLQLVNQGVKVFLATGRQFEITRPYHRQLGLTTPMICLNG 68

Query: 68  ARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKE 126
           A V D      ++  N+   I  + F  + + P     ++  D  F+ R   E  R+ +E
Sbjct: 69  AAVCDSFSAFPVYTKNV--HIKREAFHNIAEEPQCNAIIHTTDGTFVKRPSAETRRWEQE 126

Query: 127 AVFQYALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEV 184
           +  +   Y   L  L P  V K    C +H    P EQA  AR+ D+ +V        E+
Sbjct: 127 S-GKKTRYMTNLRQLPPLPVLKYSIQC-AH----PYEQAA-ARFQDQASV-IQWENGFEL 178

Query: 185 MAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           +A   SK  A + + +  G    + +A GDG ND E+L  AG G  MG+A   +K
Sbjct: 179 VAPDTSKWAAAKNLIRAYGIRKDEVLAIGDGPNDIELLQYAGTGVAMGNASDSVK 233


>UniRef50_C6CYC3 Cof-like hydrolase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CYC3_PAESJ
          Length = 265

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 72/276 (26%), Positives = 116/276 (42%), Gaps = 26/276 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y ++A D+DGTLL+ DH L+   +E ++    RG + V  TGR    V  + + L +   
Sbjct: 5   YDLIALDVDGTLLTDDHQLTSKTREAVREAADRGASIVLCTGRAPFSVFPVLEELGLTGT 64

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDD----------EW 111
           +IT NG    D D   I             +G+     +   +  R +          E 
Sbjct: 65  IITHNGGATIDSDTRRIIHE----------YGIAPQQLEPFVDYCRKNQVHYDVNTAFEM 114

Query: 112 FMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
            +    PE    + +     ++   G   PEG+ K  FT    ++++   Q    +W   
Sbjct: 115 MVESLTPEVSDMYSKFHASPSVLGQGASLPEGLVK--FTVFGSKEVMDRVQEEWEKWPPS 172

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           ++   S    ++V     SKG AL   A   G      +A G+  ND  ML  AG G  M
Sbjct: 173 LHTIRSGDFFIDVHHPEASKGRALRQFASSRGIDRSRILAIGNYYNDISMLEFAGCGIAM 232

Query: 232 GSAHQRLKDLHPELEVIG-TNADDAVPHYLRKLYLS 266
           G++   +KD     +V+G +NA+D V + LR+   S
Sbjct: 233 GNSPDGVKD---AADVVGRSNAEDGVAYALREFAWS 265


>UniRef50_A5KNX9 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A5KNX9_9FIRM
          Length = 305

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 75/276 (27%), Positives = 119/276 (43%), Gaps = 19/276 (6%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  DLDGTLL+    L+   +E L      GI  + ATGR  + V +        +Y 
Sbjct: 29  KMIGLDLDGTLLTDKKELTVRTREVLAKAIRSGIVVLVATGRPWMGVPEELREFPGMNYA 88

Query: 63  ITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +TSNGAR+ D   GN+I  H L    A     +     D +  VY D + +      E+M
Sbjct: 89  LTSNGARIIDTRTGNVIEEHLLSVKSAKKALEICR-KYDTLQEVYFDGQGYAP---AEKM 144

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR---------- 171
            F +       ++E        V  +F   D   + L   QA+ A   +R          
Sbjct: 145 EFVERYHKNPNMWEYMRKTRIPVDDIFELVDRENRGLDKTQALFADMSERKRAWEELARH 204

Query: 172 --VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
             + +  S    +EV A GV+KG  L  +  +LG   ++ +AFGDG ND  ML   G G 
Sbjct: 205 EDLELVGSLRYNIEVNAAGVNKGTGLVNLGSRLGIKREEIMAFGDGDNDTVMLKEVGFGV 264

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            M +   ++K+    + +  +N +D V   + +  L
Sbjct: 265 AMANGEPQVKEAADYITL--SNEEDGVAQAIERFVL 298


>UniRef50_B3PMC9 COF family HAD hydrolase protein n=2 Tax=Mycoplasma
           RepID=B3PMC9_MYCA5
          Length = 267

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 77/266 (28%), Positives = 114/266 (42%), Gaps = 44/266 (16%)

Query: 2   YQVVASDLDGTLLSPD-HTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           Y+++A D+DGTLL      LSP  KE  + L A G   V  TGR    VG+  +N  +  
Sbjct: 4   YKIIAFDIDGTLLPFGIDELSPRLKEMFEKLKANGYINVLCTGRDIFTVGKQINNPYV-D 62

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASD--------------LFGVVNDNPDIITNVY 106
           Y I +NG  + DL  N    +  ++ IA +               F  V +      +++
Sbjct: 63  YFIGANGTFILDLRTN---EYVFEKTIAYEDYLKFQEFAKENQLAFSFVGNKWGYYNDLF 119

Query: 107 RDDEWFMNRHRPEEMRFFKEAVFQYA-----LYEPGLLEPEGVSKVF--FTCDSHEQLLP 159
             D W+   +RP + +F     FQ       L       P+ VSK    F  D++  L  
Sbjct: 120 NIDHWY---YRPYKDKFLSVEEFQKQNDKNYLITVTCKNPQEVSKKLTKFFEDNNIDLWV 176

Query: 160 LEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDA 219
           L     A W   V +S          A  ++K   L+ +   LGYSL++ +AFGD  ND 
Sbjct: 177 L-----AEWSGGVFIS----------AREITKATGLKILTDLLGYSLEEVVAFGDSENDI 221

Query: 220 EMLSMAGKGCIMGSAHQRLKDLHPEL 245
           EML   G G  MG+     K++  E+
Sbjct: 222 EMLRAVGLGIAMGNGEDVTKEVANEI 247


>UniRef50_UPI0001AF1344 hypothetical protein SghaA1_18547 n=5 Tax=Streptomyces
           RepID=UPI0001AF1344
          Length = 314

 Score = 78.6 bits (192), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 76/246 (30%), Positives = 108/246 (43%), Gaps = 18/246 (7%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A+DLDGTLL  D ++SP     L      GI   F TGR    +  + D++      
Sbjct: 43  RLIATDLDGTLLRDDKSVSPRTVAALAAAEEAGIEVFFVTGRPARWMDVVSDHVHGHGLA 102

Query: 63  ITSNGARVHDLDGN-----LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
           I  NGA V DL G       +    L R+ A D   ++ +       VY  ++ +     
Sbjct: 103 ICGNGAAVVDLHGGPGAHRFVKVRELARENALDAVRLLREA--APGTVYAVEQTYGFHQE 160

Query: 118 PEEMRFFKEAVFQYALYEPG--LLEPEGVS---KVFFTCDSHEQLLPLEQAINARW--GD 170
           P   +   E      L  P   LL P+G +    V      H  L P      AR   GD
Sbjct: 161 PAYPKLHMEV---PDLLRPAEELLGPDGPAADEPVLKILAHHPALDPDAFLTLARLAIGD 217

Query: 171 RVNVSFSTLTC-LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           R NV+ S+ +  LE+    VSK   L     + G S ++ +AFGD  ND EML+ AG+  
Sbjct: 218 RANVTRSSPSALLEISGPEVSKASTLALCCAERGISHEEVVAFGDMPNDIEMLTWAGRSY 277

Query: 230 IMGSAH 235
            MG+AH
Sbjct: 278 AMGNAH 283


>UniRef50_C2H8K0 HAD superfamily hydrolase n=17 Tax=Enterococcus RepID=C2H8K0_ENTFC
          Length = 277

 Score = 78.2 bits (191), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 76/268 (28%), Positives = 120/268 (44%), Gaps = 12/268 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGT L+ D  ++   KETLK     G +   ATGR      Q    LE+ + M
Sbjct: 11  KLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATGRPFRMSHQFYQQLELTTPM 70

Query: 63  ITSNGARVH----DLDGNLIFAHNLDRDIASDLFGVVND-NPDIITNVYRDDEWFMNRHR 117
           +  NGA VH      DG       ++R+IA ++       N D I    RD  +  +   
Sbjct: 71  VNFNGALVHIPNQHWDGER--ETLINREIAFEILSQKKQLNLDFIAAENRDTFFIDSFDF 128

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF- 176
            +E  F      +  L  P  L     S +  T     + +  E  +  ++G  V+V   
Sbjct: 129 FDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAEAVSAE--LTRQFGSYVDVRTW 186

Query: 177 -STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
                 LE+++ G+ K   ++ +A  L    +D IAFGD  ND E+L  AG G  M +  
Sbjct: 187 GGPTAILEIVSKGIQKAKGVQEIANYLSIDQQDVIAFGDEHNDLELLDYAGWGVAMANGT 246

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKL 263
            +LK +  ++  + +N +D +  YL KL
Sbjct: 247 DQLKGIANDVTPL-SNQEDGLAVYLEKL 273


>UniRef50_C4DU72 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Stackebrandtia
           nassauensis DSM 44728 RepID=C4DU72_9ACTO
          Length = 268

 Score = 78.2 bits (191), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 73/281 (25%), Positives = 121/281 (43%), Gaps = 37/281 (13%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A+D DGTL+  D T+S    + LK L++ G+  V  TGR          +L    ++
Sbjct: 4   RLIATDFDGTLVRSDWTVSGRTNKVLKELSSLGVTIVGITGRGPRLRQLCHRDLPSADFL 63

Query: 63  ITSNGARVHDLDG---------NLIFAHNLDRDIA------SDLFGVVNDNPD----IIT 103
           + + G  V+ + G           I   ++ R +A        +  VV ++P     ++ 
Sbjct: 64  VLAQGGFVYQVSGVDDVEALHETYIPGADVARAVAIVEREVGPVKVVVENDPTHESTLVG 123

Query: 104 NVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQA 163
           ++  D  W      P  MR    A                V K F   D+ E    L  A
Sbjct: 124 DLIEDWPW------PVPMREMSRADALSG----------HVVKAFIRSDTVEAPRLLRTA 167

Query: 164 INARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLS 223
                 +  +++ + +  +E+   G++K + L  VAK+LG +  D IAFGD  ND  M +
Sbjct: 168 RELVPAELASLTDAGVGNVEICPPGINKDYGLSLVAKRLGIAASDTIAFGDAENDLSMFA 227

Query: 224 MAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            AG+   + +AH  +K    EL    +N DD V  YL KL+
Sbjct: 228 WAGRSIAVANAHDHVKAAADEL--TASNDDDGVAVYLEKLF 266


>UniRef50_B2V2P9 HAD hydrolase, IIB family n=7 Tax=Clostridium RepID=B2V2P9_CLOBA
          Length = 262

 Score = 78.2 bits (191), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 60/239 (25%), Positives = 114/239 (47%), Gaps = 2/239 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A+D+DGTLL     L     E L L+T + +  V A+GR +  +      +  K 
Sbjct: 1   MIKLIATDMDGTLLDEKGHLPESFTEVLDLITEKNVKLVIASGRPYATLQTNFGPIAKKL 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             IT NGA V+D +  LIF   +++++  D+     +  +    +      ++     E 
Sbjct: 61  SYITDNGALVYD-NNELIFKDVIEKNLVQDIIKAARNIANTAIVLCGVGCAYLENCSEEY 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++  ++   +Y + +      + + KV   CD +  +      I+  +G+ +NV  +   
Sbjct: 120 LKEIQKYYVKYEVVDDISKVEDDIIKVTL-CDLNHAIKNSNPVISPLFGNDLNVVVAGEI 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
            L++M   V+KG AL  + +    S ++ +AFGD  ND EML+ A    +M +A + +K
Sbjct: 179 WLDIMNKTVNKGTALRKIMEADNISKEETMAFGDYYNDIEMLNEADFSFVMKNAPEDMK 237


>UniRef50_Q183K1 Putative hydrolase n=5 Tax=Clostridium difficile RepID=Q183K1_CLOD6
          Length = 262

 Score = 78.2 bits (191), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 64/252 (25%), Positives = 119/252 (47%), Gaps = 25/252 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A+DLDGTLL     ++P   +  K L  RGI F  A+GR + ++ +  ++++   
Sbjct: 1   MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGRQYQNLIKKFEDIKDDM 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR--- 117
             I+ NG  V    G  I ++ L++++ +++           T   +  +  M+  +   
Sbjct: 61  MFISENGTLVV-YKGKEILSNPLNKELVNEIIET--------TRSIKGKKIVMSGKKYAY 111

Query: 118 --PEEMRFFKEAVFQYALYEP--GLLEPEG----VSKVFFTCDSHEQLLPLEQAINARWG 169
              +E  F +E    YA ++    L + EG    ++   F    H   +  E     ++ 
Sbjct: 112 IESKEEAFIQEVSTYYAKFKTVEDLTKVEGDILKIAVFDFKGAEHNNNIYFE-----KFS 166

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           DR  V  S +  L++ A G +KG A++ V K L    ++ + FGD +ND EM+  A    
Sbjct: 167 DRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEMMKSAYHSY 226

Query: 230 IMGSAHQRLKDL 241
            M +A++ LK +
Sbjct: 227 AMENANEHLKQI 238


>UniRef50_Q97F14 HAD superfamily hydrolase n=1 Tax=Clostridium acetobutylicum
           RepID=Q97F14_CLOAB
          Length = 268

 Score = 77.8 bits (190), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 68/238 (28%), Positives = 111/238 (46%), Gaps = 8/238 (3%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++ SD+D TL+  D  +S      +K   + G  F  ATGR      +   NL++   +I
Sbjct: 9   ILISDMDDTLIGSDKRISEKNLNAIKKFQSLGGRFTIATGRTMESAYRYIRNLQVDLPVI 68

Query: 64  TSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRHRPEEM 121
             NGA+++D +    IF   LD  +   +  V   +      +Y ++  ++ N  R  E 
Sbjct: 69  LYNGAKIYDFNKSKTIFEIELDDRVKEIIKKVKEYDTSFGIEIYSNENTYIYNTCRFTE- 127

Query: 122 RFFKEAVFQYALYE-PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           RF K        YE P  L  E  +KV    + +++   LE+     +G +VN+  S   
Sbjct: 128 RFKKRGY--SVFYEIPEELWKEKWTKVLVVGEKNQEDY-LEENFERLFG-KVNLVRSGEN 183

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
            LE++  G+SKG ALE +    G  +   I+ GD MND E++  AG G  + + + RL
Sbjct: 184 YLEIIPKGLSKGAALENLCNLEGVDINKVISVGDNMNDYELIKKAGYGFCVSNGNNRL 241


>UniRef50_A8MEY7 Cof-like hydrolase n=2 Tax=Alkaliphilus RepID=A8MEY7_ALKOO
          Length = 275

 Score = 77.8 bits (190), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 77/283 (27%), Positives = 129/283 (45%), Gaps = 31/283 (10%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+ +  ++   +  LK    +GI    ATGR         + L I S 
Sbjct: 3   YKLIVLDMDGTLLNRNKEVTKENQIALKKAQEKGIKVAIATGRVFTSAKFYANMLGIDSP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDR--DIASDL---------FGVVNDNPDIITN------ 104
           +I  NGA + +   N I   N  R  D+   L         F   +++   I +      
Sbjct: 63  IIACNGALIKEAASNEIIYTNPIRKEDLLKSLEIFRRHQVYFHTYDEDTIYIESLGFSSA 122

Query: 105 VYRDDEWFMNRHRPEEMRF-FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQA 163
           +Y D  W  N  + EE +   K+    Y  ++   +E     K+    +  E++L ++  
Sbjct: 123 IYND--W--NEDQSEENKIPIKKLEDSYLYFKDNPIE---TLKIMAVDEDSEKMLQIKTE 175

Query: 164 INARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLS 223
           +   +G  +N S+     LEVM  GVSKG+A+E ++K  G   ++ I+FGD  ND  M S
Sbjct: 176 LGEIYGIELNKSW--YNNLEVMNKGVSKGNAIEMLSKIYGIKREEIISFGDHFNDLSMKS 233

Query: 224 MAGKGCIMGSAHQRL-KDLHPELEVIGTNADDAVPHYLRKLYL 265
            +G    MG+A + + K+ H    +  +N +  V   + KL L
Sbjct: 234 YSGTFVAMGNAEEAVKKEAHY---ITSSNDESGVAKGIEKLVL 273


>UniRef50_A6W4K6 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Kineococcus
           radiotolerans SRS30216 RepID=A6W4K6_KINRD
          Length = 290

 Score = 77.8 bits (190), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 73/241 (30%), Positives = 105/241 (43%), Gaps = 13/241 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           + +VA+DLDGT++  +  +S             GI  V  TGR    V  + +   ++  
Sbjct: 26  WGLVATDLDGTVIPRERPVSARTLAAFAACERAGIPVVPVTGRPPRWVTPLAEEAGLRGQ 85

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++ +NGA V DLD G ++  H +  ++  ++   +      I         F  R     
Sbjct: 86  VVCANGAVVFDLDAGEVVRQHAIPVEVLREVAARLRPAMPGIGFALEAVVGF-RREAAYA 144

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCD---SHEQLLPLEQAINAR-WGDRVNVSF 176
            RF      + A +E  LL+   V KV   C    S E +     AI AR  GD VNV+ 
Sbjct: 145 TRFDGGLEQRVAPFEELLLDAPPVVKVLAKCPGTLSDEMV-----AIAAREMGDLVNVTH 199

Query: 177 STL--TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           S    + +E+MA GVSK   L  VA   G      +AFGD  ND EML  AG+   M   
Sbjct: 200 SNAADSLIEIMAAGVSKASTLAEVAGDRGVGAAGVVAFGDMPNDLEMLRWAGRSYAMADG 259

Query: 235 H 235
           H
Sbjct: 260 H 260


>UniRef50_C3WB32 Hydrolase n=3 Tax=Fusobacterium RepID=C3WB32_FUSMR
          Length = 270

 Score = 77.8 bits (190), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 69/256 (26%), Positives = 125/256 (48%), Gaps = 29/256 (11%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++ +DLD TLL+ +  +S   KE +      GI FV A+GR    +  +   LE++  
Sbjct: 3   YKIIFTDLDDTLLNSEKKISQIDKEAIMKAQEAGIKFVLASGRPTFAMYDLAKELELEKY 62

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNP---------DIITNV--- 105
            S++++ NG+ + +   G  IF  +L ++    ++    +N          +II+     
Sbjct: 63  GSFILSFNGSIITNCKSGEHIFEESLTKEDLHLMYDFAKENSCHILTYIDDEIISETESE 122

Query: 106 YRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN 165
           Y D E  + +   + ++ FKEAV + A+    L EP               L  +E+ + 
Sbjct: 123 YIDVEVTLTKMPHKIVKNFKEAVNKPAVKCMILEEPS-------------YLKEVEKKLK 169

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
            ++GD+ +++ S    LEV   GV KG AL+ + + LG  +++ IA GD  ND  ML  A
Sbjct: 170 EKYGDKYSIAISKPFFLEVTKLGVDKGVALKNLVETLGMKIEESIAVGDSYNDLPMLKAA 229

Query: 226 GKGCIMGSAHQRLKDL 241
           G    + +A++ +K +
Sbjct: 230 GLAACVENANEDIKKV 245


>UniRef50_C7HWS9 Cof family protein n=2 Tax=Anaerococcus RepID=C7HWS9_9FIRM
          Length = 271

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 71/271 (26%), Positives = 126/271 (46%), Gaps = 13/271 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS-- 60
           ++VA DLDGTLL+ D  +S    E +K L  +GI  V ATGR       I D+LE+ S  
Sbjct: 6   KLVAIDLDGTLLNSDKKVSRKNFEIIKKLRVKGIFVVIATGRPLGGFSWILDDLELNSDD 65

Query: 61  -YMITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y IT+ G+ +  + D + +    L  +   +L  ++ND   I   +Y     + N  R 
Sbjct: 66  DYSITNTGSLIIKNKDKSDVSKKILSMEDYLNLKKIINDKLQI--GIYNKYNLYSNSERV 123

Query: 119 EEMRFFKEAVFQYALYEPGLLE-PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
            +   F+  + +  + +    +  + V ++  T +  + +   E+  N           +
Sbjct: 124 NKHFLFESEILKMPIEKIDEKDMSKRVDRITITGN-KDAVDEFEKNYNEMLLKTYQTVRN 182

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
                EV+     KG AL+ + K L   LK  +A GD  ND  ML+MAG     G+  + 
Sbjct: 183 VPEVFEVLHKEADKGQALKRLCKILNVDLKSTLAIGDSNNDKTMLNMAGVSATCGNGRES 242

Query: 238 LKDLHPELEVIG--TNADDAVPHYLRKLYLS 266
           +K++   ++++   +N +D V + L K++ +
Sbjct: 243 VKEM---VDIVSNYSNDEDGVCNILEKIFFA 270


>UniRef50_A6LZV6 Cof-like hydrolase n=1 Tax=Clostridium beijerinckii NCIMB 8052
           RepID=A6LZV6_CLOB8
          Length = 285

 Score = 77.8 bits (190), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 82/270 (30%), Positives = 125/270 (46%), Gaps = 51/270 (18%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS-- 60
           +++A DLDGT+L+    +S      +K+   +G+  V ATGR    VG I D  EIKS  
Sbjct: 4   KLIALDLDGTVLNSCGYISDKTLTAIKMAIEKGVQVVLATGRS---VGLICD--EIKSIE 58

Query: 61  ---YMITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIIT-----NVYRDDEW 111
              Y I+SNGA V +L  N ++F++ +  DI   +  ++ D P ++      N Y D+E 
Sbjct: 59  EITYAISSNGAAVVNLRKNEMVFSNFITIDILKKIIKIIKDYPIVVEFYSNGNAYIDEEV 118

Query: 112 FMNRHRPEEMRFFKEAVFQYALYEPGL-LEPEG---VSKVFFTCD--SHEQLLPLEQAIN 165
           F+N   P           +Y L E  L L  +    +  +F   D  S  + +   + IN
Sbjct: 119 FIN---P----------VKYGLSEKCLNLMSDSHNLIKNIFSVVDDRSECEWIKCVEKIN 165

Query: 166 ARW----------------GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDC 209
             +                 D+V ++ S    LE+     +KG  LE + + L   LK+ 
Sbjct: 166 IPFLKDDMKNEVYNSLLSINDKVKITSSVEDNLEINIHSANKGAGLEKLTELLEIDLKEI 225

Query: 210 IAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
            A GD  ND EML MAG G  MG+A + +K
Sbjct: 226 AAIGDNNNDIEMLQMAGIGIAMGNASEDIK 255


>UniRef50_C5WEL1 Putative uncharacterized protein n=1 Tax=Streptococcus dysgalactiae
           subsp. equisimilis GGS_124 RepID=C5WEL1_STRDG
          Length = 271

 Score = 77.4 bits (189), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 78/283 (27%), Positives = 132/283 (46%), Gaps = 33/283 (11%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQ++A D+DGTLL+   T+S  + + +          V ATGR   ++   R +L    
Sbjct: 1   MYQLIAFDMDGTLLTSQQTISTVSLKAINQAIQAKKQVVLATGRPLSEIKPYRQDLASLQ 60

Query: 61  YMITSNGARVHDLDGN---------LIFAHNLDRDIAS-DLFGVV-NDNPDII--TNVYR 107
           Y I  +GA ++DL            LIF   L +     D+  VV +++   I  ++   
Sbjct: 61  YAILESGAVIYDLQEERMIHQVSLPLIFLQQLLQSTEGLDVMVVVMSESQSYIQESHFLS 120

Query: 108 DDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKV---FFTCDSHEQLLPLEQAI 164
            + ++M+++   +M +   AVF   ++     + E + KV   F T  + +  L      
Sbjct: 121 IENYYMDQY---QMLYQATAVFVDDIHSLLADKKEKIEKVNLYFKTVKTRDHYL------ 171

Query: 165 NARWGDRVNVSF--STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
                D + V+   +  T +E+ A GV+KG AL  +   L   ++  IA GDG ND +M+
Sbjct: 172 --ESMDYLQVAAIKAEKTGIEITARGVNKGQALIFLVNYLQLEIEQTIAVGDGDNDRQMI 229

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNAD---DAVPHYLRK 262
           + AG G  MG+A+  +K L  + EV   + D    A+  +L K
Sbjct: 230 AEAGLGIAMGNANTTIKTL-AKAEVASNDKDGCAQAIYQFLLK 271


>UniRef50_C4Z320 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=C4Z320_EUBE2
          Length = 268

 Score = 77.4 bits (189), Expect = 4e-13,   Method: Compositional matrix adjust.
 Identities = 65/249 (26%), Positives = 114/249 (45%), Gaps = 18/249 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
           Y+ +A DLDGTL + +  +    KE +      G+  + A+GR    +  I   LE+   
Sbjct: 3   YKALALDLDGTLTNREKKVPAGNKEAIAKAIDAGVKVILASGRPLFGITPIARELELDKK 62

Query: 61  --YMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y++  NG  + D   G  + A  + +D  +D+  +   N  +    Y D +       
Sbjct: 63  GGYILAYNGGCIVDCKTGKQMSATIMPQDCIADICSLARAN-GVYALTYADTQIAAESDS 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKV-------FFTCDSHEQLLPLEQAINARWGD 170
            E ++  KEA+         + + + + K        F     HE+LLP+++A+  +   
Sbjct: 122 DEYVK--KEAICN----STTIKKVDDLRKFVDYPVEKFLVVGEHEKLLPVQKALLDKHEG 175

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            +N  FS    LEV+  GV+K  +L+ +   L  + ++ +A GDGMND  ML  AG   +
Sbjct: 176 VINAFFSESYFLEVVPAGVAKDASLDKLLTMLDITSEELVACGDGMNDIPMLKYAGLAAV 235

Query: 231 MGSAHQRLK 239
           M +A+  +K
Sbjct: 236 MENAYPEVK 244


>UniRef50_C4V675 HAD superfamily hydrolase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V675_9FIRM
          Length = 278

 Score = 77.4 bits (189), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 64/246 (26%), Positives = 103/246 (41%), Gaps = 23/246 (9%)

Query: 7   SDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSN 66
           SDLDGT+L     +S      ++     G+    ATGR       + + L +   +I  N
Sbjct: 8   SDLDGTMLPSGDIVSSENIAAVQCAVRAGVTVTIATGRMFEAALPVAEALGVDVPIIAYN 67

Query: 67  GARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP-------- 118
           GA +    G +   H +D  +A D           I    +   W++  +          
Sbjct: 68  GALIKSPSGRIYEEHAIDPMLARD-----------IITFAQARGWYIQSYSGGVLRYAIA 116

Query: 119 -EEMRFFK--EAVFQYALYEPGLLE-PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
            EE RF++  + +   A+   G+L    G  K+    +         Q +   +G  + V
Sbjct: 117 CEESRFYENSQKITGKAVGRNGMLAYVTGNCKLLLVTEGRAVSEARAQMLMDAFGAHIGV 176

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           + S    +E++  GVSK  AL A+A KLG +  + +A GD  ND  ML  AGK   MG+A
Sbjct: 177 TRSADRLVEIVVKGVSKASALTALAAKLGITADETMAIGDAYNDLPMLKAAGKSVAMGNA 236

Query: 235 HQRLKD 240
              +K+
Sbjct: 237 FPEVKE 242


>UniRef50_B2GGK0 Putative uncharacterized protein n=1 Tax=Kocuria rhizophila DC2201
           RepID=B2GGK0_KOCRD
          Length = 411

 Score = 77.4 bits (189), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 73/248 (29%), Positives = 102/248 (41%), Gaps = 28/248 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ASDLDGT+L PD    P   E +      GI  VF TGR    +  + + L+    +
Sbjct: 14  RLIASDLDGTVLGPDFRFRPRTLEAITAARDAGIQVVFVTGRPKRWLDPLHEQLDDAGVV 73

Query: 63  ITSNGARVHDLDGNLIFAHN-------------LDRDIASDLFGVVNDNPDIITNVYRDD 109
           I SNGA V D     + + N             + R     LF       + +  V+ D 
Sbjct: 74  ICSNGAVVFDPGTQRVLSANGFDVAEALPVIEDVRRAFPDSLFAA-----ETLEAVHTDH 128

Query: 110 EWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
            W        E+R   EA     L  PG      V K+    D  +     E   +   G
Sbjct: 129 GWARTDRM--EIRDVTEAPVTETL-RPGT----AVVKLLAKLDGADPDTYFEAVRDVVAG 181

Query: 170 DRVNVSFSTLTCLEVMAG--GVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
            R+ V+ S      V  G  G++K   LE  A +LG S  + +AFGD  ND EML+ AG+
Sbjct: 182 -RLAVTHSVAAAPLVEMGQRGLTKARTLERFAAELGISRHEVMAFGDMPNDLEMLTWAGR 240

Query: 228 GCIMGSAH 235
           G  M   H
Sbjct: 241 GYAMADGH 248


>UniRef50_C5RCK1 HAD superfamily hydrolase n=1 Tax=Weissella paramesenteroides ATCC
           33313 RepID=C5RCK1_WEIPA
          Length = 272

 Score = 77.4 bits (189), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 73/270 (27%), Positives = 119/270 (44%), Gaps = 11/270 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  DLD T L+    +S   ++ ++ +   G      TGR       I   L +KS M
Sbjct: 4   KLIGIDLDRTTLNDAGEVSERTRQAIQKMQQAGHVVAIITGRPVRLSMDIYQQLGLKSPM 63

Query: 63  ITSNGA--RVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFMNRH--- 116
           I  NGA   + +   +  +++ +DR+IA DL     D     +    R D W  N H   
Sbjct: 64  INFNGALGEIPNELWDYAYSYQVDREIAFDLIENAADMAIKSVVAESRADVW-TNSHIGP 122

Query: 117 -RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             P E  FF ++   Y + +   L+    S +    +S  Q L  +   N    DRV V+
Sbjct: 123 TNPNEAFFFPQSTDTYHMLDRLNLKTNINSILIEAQNSTHQALIQDYVTNRYGSDRVTVN 182

Query: 176 F--STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              +    LE++  GV+K   L+ + +       D  AFGDGMND EM+  A  G +M +
Sbjct: 183 TWGADSPVLEIVPAGVAKDTGLQIMQRAFDIKKDDVYAFGDGMNDYEMIDYATHGVVMKN 242

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
               LK +  ++    TN +D +  YL ++
Sbjct: 243 GQPALKAIANDITSY-TNDEDGLAKYLEQI 271


>UniRef50_P44447 Uncharacterized protein HI0003 n=16 Tax=Haemophilus influenzae
           RepID=Y003_HAEIN
          Length = 262

 Score = 77.0 bits (188), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 61/243 (25%), Positives = 112/243 (46%), Gaps = 9/243 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V SD +GTLL+  HT+SP     +K LTA GI FV  + R  + +      LE  +
Sbjct: 2   MYKAVFSDFNGTLLTSQHTISPRTVVVIKRLTANGIPFVPISARSPLGILPYWKQLETNN 61

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            ++  +GA + + +   I++  ++     ++  V+ ++P +  N Y +++    R    +
Sbjct: 62  VLVAFSGALILNQNLEPIYSVQIEPKDILEINTVLAEHPLLGVNYYTNNDCHA-RDVENK 120

Query: 121 MRFFKEAVFQYALY---EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
              ++ +V +  ++   E     P  +  +    +  E  + L++         +++  S
Sbjct: 121 WVIYERSVTKIEIHPFDEVATRSPHKIQIIGEAEEIIEIEVLLKEKF-----PHLSICRS 175

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LEVM    +KG A+  +    G    + IAFGD  ND +ML   G G  MG+A   
Sbjct: 176 HANFLEVMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHVGLGVAMGNAPNE 235

Query: 238 LKD 240
           +K 
Sbjct: 236 IKQ 238


>UniRef50_Q7MBY0 Predicted hydrolase n=44 Tax=Gammaproteobacteria RepID=Q7MBY0_VIBVY
          Length = 336

 Score = 77.0 bits (188), Expect = 6e-13,   Method: Compositional matrix adjust.
 Identities = 67/251 (26%), Positives = 107/251 (42%), Gaps = 16/251 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+V+A DLDGT+L+ DH++ P  K  + +      + V  TGRHH       D L + +
Sbjct: 64  MYKVLALDLDGTVLTDDHSIHPEVKSAI-MEAKHKCHVVIVTGRHHTAARPYYDELGLTT 122

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            +I  NG  V+D   + +  HN      +  F  +     +   +Y  D    + + P  
Sbjct: 123 PIICCNGTYVYDYHNDQVLKHNSINKEDALTFIALAKEFQVKMVMYVTDAMTYSNYNPIH 182

Query: 121 MRFFKEAVFQYALYEPGLLEP---------EGVSKVFFTCDSHEQLLP--LEQAINARW- 168
              + EA+ ++A   P   +P         + V    +      + LP  +E+ +   W 
Sbjct: 183 ---YMEALEKWAKTAPKHHQPKIYKIDSFSDQVRDTEYVWKFVVEGLPSSVERLLENPWV 239

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
             + N   S    ++  A G SKG  L     +LGY     IA GD  ND  ML  AG G
Sbjct: 240 SAKFNGERSWSNRIDFAAKGNSKGLRLAEYVSELGYHPNHVIAVGDNHNDISMLRYAGLG 299

Query: 229 CIMGSAHQRLK 239
             M +A + ++
Sbjct: 300 VAMNNADETVR 310


>UniRef50_Q5HPL1 Hydrolase, haloacid dehalogenase-like family n=64
           Tax=Staphylococcus RepID=Q5HPL1_STAEQ
          Length = 268

 Score = 76.6 bits (187), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 71/270 (26%), Positives = 128/270 (47%), Gaps = 15/270 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y++V  D+D TL++ D+ LS   K  L  +  RG   V A+GR    +      LE+   
Sbjct: 4   YKMVVLDMDDTLMNSDNKLSIETKSYLLDIQKRGYYVVLASGRPTEGMLPTARELELNKY 63

Query: 60  -SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVND---NPDIITNVYRDDEWFMNR 115
            S++I+ NG +  ++    +    +D+ ++ + F  + D   + + +   Y D+ + ++ 
Sbjct: 64  NSFIISYNGGKTINMANENV---EVDQPVSKEDFDNIVDYCRDKNFLVLTY-DNGYIIHD 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
              E M    +           L E     V KV    D    +      ++  + + ++
Sbjct: 120 SSHEYMNIESQLTGLPMNRVADLKEYINHSVPKVM-GVDYVGHITEARIELDGYFNNDID 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V+ S    LE MA  VSKG+A++A+ K+L  SL++ I FGD +ND  M  +AG    MG+
Sbjct: 179 VTTSKPFFLEFMAKNVSKGNAIKALCKRLQISLEEVIVFGDSLNDKSMFEVAGYSVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           A   LK +  E+ +   N  + +P+ L++L
Sbjct: 239 ASDELKKIADEVTL--DNNSNGIPYALKEL 266


>UniRef50_Q5HRI8 Hydrolase, haloacid dehalogenase-like family n=67
           Tax=Staphylococcaceae RepID=Q5HRI8_STAEQ
          Length = 292

 Score = 76.6 bits (187), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 83/293 (28%), Positives = 125/293 (42%), Gaps = 40/293 (13%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A+D+DGTLL+  H ++   +E +K   A GI  V ATGR   +        ++K 
Sbjct: 1   MIKLIATDMDGTLLNAGHEITTMNQEAIKFAQANGITVVIATGRAFYEAQTPVAETDLKV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP---DIITN--VYRDD------ 109
             I  NGA V D   N++   +L+ D+   +   + +N     I TN  +Y +D      
Sbjct: 61  PYICLNGAEVRDESFNIMSTSHLNHDLVHKITTALKNNHIYYQIYTNRGIYTEDPKRDLA 120

Query: 110 ------EWFMNRHRPEEMRFFKE---------AVFQYALYE--PGLLEPEGVSKVF-FTC 151
                 E    +   +++R   +          V  Y   E  PG    E + KV  F  
Sbjct: 121 IYIDIAERAGQKADVDKIRNNIQKRIDNGTLKVVDNYDSIEDIPG----ELIMKVLAFDA 176

Query: 152 DSHEQLLPLEQAINARWGD-RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCI 210
           D    L  ++Q   A      + VS S+   LE+      KG AL A+A +LG  L D I
Sbjct: 177 D----LSKIDQVGQALASSPNLAVSSSSRGNLEITHSNAQKGIALSAIAHQLGIDLTDVI 232

Query: 211 AFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           A GD +ND  ML   G    M +A   +K  H    V  TN +  V   + K+
Sbjct: 233 AIGDNLNDISMLERVGYPVAMNNATDEVK--HIAKYVTDTNENSGVGKAIMKI 283


>UniRef50_Q04GT8 Predicted hydrolase of the HAD superfamily n=2 Tax=Oenococcus oeni
           RepID=Q04GT8_OENOB
          Length = 271

 Score = 76.6 bits (187), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 71/279 (25%), Positives = 124/279 (44%), Gaps = 27/279 (9%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR-------HHVDVGQIRDN 55
           ++VA D+D TLL+  + L+ +  +TLK   A G   V  +GR       ++  +G  + +
Sbjct: 4   KLVAIDVDATLLNSRNELTKHTIDTLKEAIAMGTKIVITSGRPLPGTEPYYAKLGIDKKD 63

Query: 56  LEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVN--------DNPDIITNVYR 107
                Y I  NGA +    G +I    L      D++ + N        +  D I   Y 
Sbjct: 64  ---DQYAINYNGATIRTTSGRMISEATLTIKDYKDIYSLANKIGVKIQAETADCIYTPY- 119

Query: 108 DDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
                  ++   E +     +    + +  L + + ++K+ F  D  E +  +++ + A 
Sbjct: 120 ---LSAPKYTKYEQKLTNAKIRHVRMQD--LKKSDVIAKIMF-IDEPEIISRVKKELPAW 173

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
             DR NV  S+   +E +   VSKG+A+  +A+KLG  +   +A GD  ND  M+  AG 
Sbjct: 174 VYDRFNVVPSSPVYIEFIDKKVSKGNAVRTLAEKLGIDISQVMAIGDQGNDLSMIEAAGV 233

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           G  MG+    LK +     V  +N +D V + + K  L+
Sbjct: 234 GVAMGNGIDDLKSIAQ--FVTKSNDEDGVAYAVEKFLLN 270


>UniRef50_C9LLD7 HAD hydrolase, IIB family n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LLD7_9FIRM
          Length = 266

 Score = 76.6 bits (187), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 62/227 (27%), Positives = 103/227 (45%), Gaps = 4/227 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-SY 61
           ++ A DLDGTLL  D +LS ++K+ ++    RGI+ V ATGR         + L +  + 
Sbjct: 4   KMAAIDLDGTLLHDDMSLSDFSKDIIRKAEHRGIHIVLATGRMFDAARPKAEELGLSDTP 63

Query: 62  MITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I   GA +     G  I+   +D  +A  +     +   ++ + + DD+ ++      E
Sbjct: 64  LICYTGAWIMMSRSGRPIWQDGIDISVAEKILLTAREKGWLV-HTFFDDQIYLPEPNKTE 122

Query: 121 MRFFKEAVFQYALYEPGLLEPEGV-SKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            ++ K      A        P+   +++ F   S      + + I   + D V V F   
Sbjct: 123 AKYKKYRTKAVAYLGNAFYHPKKKPTRLIFADGSEAVRREIRRVIETNFSDEVEVVFPGD 182

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
             ++V   GVSKG AL+ +      SL + IAFG+  ND  ML MAG
Sbjct: 183 DFVDVHKKGVSKGTALQKLCNMWDISLSEVIAFGNTENDVSMLKMAG 229


>UniRef50_C7HRV4 Hydrolase (HAD superfamily) n=1 Tax=Anaerococcus vaginalis ATCC
           51170 RepID=C7HRV4_9FIRM
          Length = 272

 Score = 76.6 bits (187), Expect = 9e-13,   Method: Compositional matrix adjust.
 Identities = 68/272 (25%), Positives = 124/272 (45%), Gaps = 8/272 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR---HHVDVGQIRDNLE 57
           M +++A+D D TLLS D T+     + +K     GI    ATGR      D+ +  DN++
Sbjct: 1   MIKLIATDCDETLLSDDKTIHKRNIDAIKKAQEMGIIITTATGRGPYQLFDILEQIDNVK 60

Query: 58  IKSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              + I  NG  + D +   ++ A  +D   A ++     +   +   +Y D   ++  +
Sbjct: 61  EDRFSILCNGGIIMDNVTKKVVEASPIDYKKAVEISDYCKE-VGVHFEIYTDKHCYVFVN 119

Query: 117 RPEEMRFFKEAVFQYALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
             E    + + ++++      +  L+ E + KV     +   L+ LE+ I       +++
Sbjct: 120 GNEVEGNYDKNIYKFVQKAKDIKNLDKEIIVKVIIKNSNLNYLMSLEEDIARICNWDISI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           S+S+ T +E+    V+K  ALE +    G  +++ +  GD  ND EML  AG    + +A
Sbjct: 180 SYSSDTFMEINRKNVNKAKALEKLCAHYGIGMENVLTIGDNYNDKEMLEEAGYSAAVQNA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           H  LKD+  +     TN   AV   + K  L+
Sbjct: 240 HLLLKDI-SKYTTKATNNQGAVGEAIEKFVLN 270


>UniRef50_C2D871 Sugar-phosphatase n=1 Tax=Atopobium vaginae DSM 15829
           RepID=C2D871_9ACTN
          Length = 266

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 71/272 (26%), Positives = 116/272 (42%), Gaps = 21/272 (7%)

Query: 3   QVVASDLDGTLLSPDHTL-SPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           ++VASD+DGT L  +     P  K  L  +T +G  FV A+G  ++ + Q          
Sbjct: 6   KLVASDMDGTFLRDNKEFDEPRFKRILHRMTQQGARFVLASGNQYIQLKQSFPGYADTLS 65

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRHRPEE 120
            +  NG  V D  G LI+  +LD      ++  V  +P++ T    +   ++  RH   E
Sbjct: 66  YVAENGGYVVD-SGKLIYTAHLDEKDLRAIYNTVMPDPNLYTIFCGEHASYIEKRHATPE 124

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTC--------DSHEQLLPLEQAINARWGDRV 172
                +  F        LLE      +   C        DS+ Q+L       A+    +
Sbjct: 125 FIGLVKYYFPSLEIVDNLLEIN--DNILKACEVMQPDDTDSYYQML------RAQLPSHI 176

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
             + S    ++++  G++K   ++ + K+   + K+CIAFGD  ND EMLS  G G  M 
Sbjct: 177 IPTTSGHGSIDLILTGINKAFGIDLLVKRWNITPKECIAFGDAANDIEMLSYVGCGYAMA 236

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A   + D   +     +N DD V   L  L+
Sbjct: 237 NAMDGIADYAQKQA--PSNNDDGVLEVLDTLF 266


>UniRef50_A7GS76 Cof-like hydrolase n=73 Tax=Bacillus RepID=A7GS76_BACCN
          Length = 272

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 65/270 (24%), Positives = 115/270 (42%), Gaps = 22/270 (8%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++  SD+DGT++     +       L+ L    I   FA+GR   ++  +   +    
Sbjct: 1   MIKMFVSDIDGTMMQHGGLIDKEDIAALRSLAEHNIILCFASGRLDNEIADLMKEVGTHF 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           + I+ NG  V+  +   + +   D +I  DL  + N+ P      Y  DE   N +  E+
Sbjct: 61  HRISVNGVFVYTHENKQLLSATFDSEILPDLLSMTNEEPYF---RYVSDEH--NYYIEEK 115

Query: 121 MRFFKE---AVFQYALYEPGLLE-------PEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
             F  E    V   ++ EP LL+       P  +S       + E L  L++ IN  + +
Sbjct: 116 TPFIHELEKQVTMTSIEEPNLLKKIDDTIFPNKIS----VGGTKEDLQILQKKINETFKN 171

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           +V+   S   CL+VM   +SKG A+  ++++   + ++    GD  ND  M  +      
Sbjct: 172 KVSTFISAEQCLDVMPPNISKGSAISVLSEEFQITPEEIACIGDSYNDIPMFHLTPHSFA 231

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
           M  A + +K      + +  +  DAV H L
Sbjct: 232 MSQADEEVKK---HAKHVVPSVKDAVKHVL 258


>UniRef50_C8P8B9 Sugar phosphatase SupH n=1 Tax=Lactobacillus antri DSM 16041
           RepID=C8P8B9_9LACO
          Length = 267

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 65/281 (23%), Positives = 121/281 (43%), Gaps = 38/281 (13%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETL-KLLTARGINFVFATGRHHVDVGQIRDNLEIK 59
           M + +A+D+DGT L+ + T       T+ +L+  R + F+ A+G  +  +  +   +  +
Sbjct: 1   MIRAIATDIDGTFLTTNRTYDHQLFNTVFQLMQQRNVKFIVASGDQYYFLRSLFPAIANQ 60

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
              +  NG    D  G  I    L+R + +D+   ++  PD    V      ++    PE
Sbjct: 61  IAFVAENGVLTVD-RGEEIACGQLNRSVVADIIADIDALPDTYYVVCGRQFAYVKETMPE 119

Query: 120 EMR-----------------FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQ 162
           + +                 F  + +F++AL  P    P  +  +     +H+       
Sbjct: 120 KFKQGLHRFYTRTKVVKDFSFLNDKIFKFALVVP----PANMRTI-----AHD------- 163

Query: 163 AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
            IN ++   +  + S    ++++   + K + L+ +  +   S  D +AFGDG ND EM 
Sbjct: 164 -INTKFAGIIRATASGNGAIDLIIPEMDKSYGLKKLLDRWQISPADLVAFGDGENDLEMF 222

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            +AG    MG+A   ++      + IGTN + AV H L KL
Sbjct: 223 DLAGTSYAMGNAPANVR--AAASQTIGTNDEQAVLHELEKL 261


>UniRef50_B0MA15 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0MA15_9FIRM
          Length = 294

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 70/271 (25%), Positives = 117/271 (43%), Gaps = 37/271 (13%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++++SD+DGTLL     ++    + ++ L   G+ F+  TGR + +V  I     ++ 
Sbjct: 1   MIKLISSDMDGTLLDSYRQITQVNIDAIRTLQDSGVEFIINTGREYQNVTDILGKAGLEC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR----H 116
            MI SNG+  +D +GNL+F H++  D    + GV + +  + T   +     M R     
Sbjct: 61  DMICSNGSCGYDKEGNLLFEHSIPADTVKQILGVFHKSSLVPTPFSQ-----MGRISLLS 115

Query: 117 RPEEMRFFKEAVF------------------------QYALYEPGLLEPE-GVSKVFFTC 151
           R E  ++ KE +                          Y   E GL + E  V K     
Sbjct: 116 REELKKYTKEVMIPSMQINHPDFVYTDEEFEDLISQVTYVEGEAGLFDSEHRVLKFISQS 175

Query: 152 DSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIA 211
              E LL L   +    G  + V  +  T +E+ +    KG  L   AK+ G    + +A
Sbjct: 176 TDPEALLRLRAELEQIPG--LAVVSTAPTDIEITSSEAQKGIGLMDYAKRKGLVPDEIVA 233

Query: 212 FGDGMNDAEMLSMAGKGCI-MGSAHQRLKDL 241
            GD  ND  MLS+ G   + M +A + +K++
Sbjct: 234 IGDSENDYSMLSIPGIHSVAMANATEAIKNI 264


>UniRef50_UPI000196AEDD hypothetical protein CATMIT_00603 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196AEDD
          Length = 275

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 72/274 (26%), Positives = 126/274 (45%), Gaps = 23/274 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLDGTL + ++ ++   +ETL      G   V A+GR    +      LE++ Y
Sbjct: 3   YKLIALDLDGTLKNSENKITDATRETLIKAQQLGATVVLASGRPTPGLRHEAAALELEKY 62

Query: 62  ---MITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRD-------DE 110
              +++ NGA+V D      +F   L  + A   +     +   I   Y D       D+
Sbjct: 63  EGYLLSFNGAKVMDAKTRQTMFEQRLTVEQAKKAYDEAKKHNLAIMTYYDDAVYTEDVDD 122

Query: 111 WFMN-RHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
            ++N      ++   K   F+  L +P       ++KV  T D       LE   +A  G
Sbjct: 123 QYVNIEGHINDIEIKKAESFKSILRDP-------INKVLCTGDPEHVASVLEDYKSAFLG 175

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
             +++  S    +EVMA  + K  +L+ + K L  + ++ IAFGDG ND  ++  AG G 
Sbjct: 176 --LSIYRSAPFFIEVMAPNIDKAASLDKLVKMLHLTKEEVIAFGDGFNDLSLIEYAGCGV 233

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            M +A   +K+    + +  +N +D + + L+KL
Sbjct: 234 AMANAVDEVKERADVVTL--SNDEDGIAYMLKKL 265


>UniRef50_A8UBX5 Putative uncharacterized protein n=1 Tax=Carnobacterium sp. AT7
           RepID=A8UBX5_9LACT
          Length = 269

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 74/274 (27%), Positives = 135/274 (49%), Gaps = 13/274 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A D+DGTLL+  H ++   K+ +K  +  GI  V  TGR    V    + L++  
Sbjct: 1   MIKLIAIDMDGTLLNEHHLVTDKVKKAIKEASNAGIKIVLCTGRPVHAVYDYFEELDLPK 60

Query: 59  --KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDE-WFMN 114
             + Y+I+ NG  V    +  ++++H LD         ++   P  +   Y D++ ++  
Sbjct: 61  DEEDYVISLNGTVVQKTTNWEIVYSHQLDHSQLKKAEQLIE--PFEMNFTYFDEKAYYYT 118

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPEGVS--KVFFTCDSHEQLLPLEQAINARWGDRV 172
             + E ++F  + +   A++ P    PE ++  K  +  +  E L  L  ++ A   +  
Sbjct: 119 GKKTEMLQFDADLLGMDAVHLPLEELPEELTIFKAMYVAEETE-LDHLAASMPAFISENF 177

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
               S    LE++  G +KG AL  +A KLG+S+ + +A GDG ND +M+ +AG    MG
Sbjct: 178 YPIRSLSYVLELLPQGANKGEALTGLATKLGFSMDEVMAIGDGENDLDMMKVAGTSVAMG 237

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +A   +K L  +  V  +N +D V H + +  L+
Sbjct: 238 NAVDSIK-LTAKY-VSKSNQEDGVAHAIYEWALN 269


>UniRef50_C7N949 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7N949_LEPBD
          Length = 274

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 76/279 (27%), Positives = 120/279 (43%), Gaps = 20/279 (7%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR-------HHVDVGQIR 53
           M +++A D+DGTLL+    +    KE +      GI  V  TGR        + ++G   
Sbjct: 1   MIKLIAIDMDGTLLNEKKHIEKAQKEAIHEAIEAGIKIVLCTGRPLYGILPFYKELG--L 58

Query: 54  DNLEIKSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF 112
             L+ + Y+I +NG  VH   D  LI    +  D    L+   ++  DI   +  +  +F
Sbjct: 59  QELDQEGYVILNNGCSVHKTKDWELIECAEITPDDMEHLYKF-SEKYDINFTLVDETHYF 117

Query: 113 MNRHRPEEMRFFKEAVFQYALYEPGLLEPEG-----VSKVFFTCDSHEQLLPLEQAINAR 167
            N  R        +A F ++      LE        + KV F  D  E++   +      
Sbjct: 118 -NIGRKPTKELIMDAQFVFSDITDITLEEAKSGKYKIVKVMFLGDP-EEMKKFQTEYEDM 175

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
             +R     S     EV+  G +KG  L+ +A+KLG   ++ +A GDG ND EML  A  
Sbjct: 176 IKERYEGVLSQSYVYEVLPKGYNKGTGLKNLAEKLGIKQEEVMAIGDGNNDVEMLEYANY 235

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           G  MG+A +  ++         TN +D V   +RK  L+
Sbjct: 236 GVAMGNASKLARNAAK--YTTDTNENDGVAKAIRKYALN 272


>UniRef50_Q6NEN3 Putative uncharacterized protein n=1 Tax=Corynebacterium
           diphtheriae RepID=Q6NEN3_CORDI
          Length = 275

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 76/266 (28%), Positives = 112/266 (42%), Gaps = 43/266 (16%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  ++ SD+DGTL+     +    KE+L      G++FV ATGR    +  I D L    
Sbjct: 1   MSALIVSDIDGTLIDSRERIPSAVKESLAAAQRAGVSFVVATGRPARWIHPIIDQLYTPP 60

Query: 61  YM-ITSNGARVHDLDGNLIFAHN------------LDRDIASDLFGV----------VND 97
            + + +NGA ++D   + I                + R+  SDL G            +D
Sbjct: 61  TLCVCANGAVIYDPACDSITHRRELAPDAMRTVVRVAREALSDLGGCGVGVERAGVSAHD 120

Query: 98  NPDIITNVYRD--DEWFMNRHRPEEM-RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSH 154
            P  +  V  D    W    H   E+ R    +  +  L    L   +           H
Sbjct: 121 MPGELFMVTPDFVHSWESIEHSTVELDRVLARSAVKLLLRNDALTSEQ----------MH 170

Query: 155 EQLLPLEQAINARWGDRVNVSFSTLT-CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFG 213
             + P+  A      D  +V++S     LEVM  GV+K  AL+ VA+ LG    D IAFG
Sbjct: 171 RLVAPVVPA------DVAHVTYSMPDGLLEVMQPGVNKSSALDVVAQDLGVDPADAIAFG 224

Query: 214 DGMNDAEMLSMAGKGCIMGSAHQRLK 239
           D +ND EM+  AG G  MG+A  +L+
Sbjct: 225 DMLNDLEMIRWAGTGVAMGNACDQLQ 250


>UniRef50_UPI0001BC55F4 hypothetical protein FulcA4_13722 n=1 Tax=Fusobacterium ulcerans
           ATCC 49185 RepID=UPI0001BC55F4
          Length = 267

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 63/267 (23%), Positives = 132/267 (49%), Gaps = 10/267 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ SD+DGTLL   H +    K+ +K +  +GI F+  + R    +  I+   +++S 
Sbjct: 4   YKMIFSDIDGTLLDSTHQVRENTKKKIKEIEKKGIPFILVSARMPEGIYTIQKAADLESP 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDN-PDIITNVYRDDEWFMNRHRPEE 120
           ++  +G  V D D  +I ++ + +  A ++ G + +   ++  ++Y    W ++ +R + 
Sbjct: 64  IVAYSGGLVLDTDRKIIKSNGMSQKKADEITGYIKEKWNNMCISIYSGSLW-ISFNRSDC 122

Query: 121 MRFFKEAVFQYALYEPGLLE----PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
               +E +      E   ++       V K+    D  E++  +E  +  ++ + ++V  
Sbjct: 123 WIRQEEEITTLKCIEGNFIDILENNTDVHKIMCMGDP-EKIAEIENILKIKYPE-LSVYR 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S  T LE+M G   K +A++ + +    S+++ I+FGD  ND +ML+  G G  MG+A  
Sbjct: 181 SKDTYLEIMDGKTLKSNAVKVLCEIKNISIEETISFGDNFNDIDMLTATGMGVAMGNAPD 240

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKL 263
            +K    ++ +   N  + + H L KL
Sbjct: 241 EVKKYADKITL--DNDSEGLLHMLEKL 265


>UniRef50_A8RS01 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A8RS01_9CLOT
          Length = 261

 Score = 75.9 bits (185), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 66/255 (25%), Positives = 124/255 (48%), Gaps = 33/255 (12%)

Query: 1   MYQVVASDLDGTLL---SPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLE 57
           M +++ SD+DGTL+   SPD  L P   + +  L  +G+ FV A+GR    V    + ++
Sbjct: 1   MIKLIVSDVDGTLVPDGSPD--LDPEVFDIILKLREKGMQFVVASGRPWASVESAFEPVK 58

Query: 58  IKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVY----------R 107
            K + + +NGA V    G  ++A+ ++R++A  +   V  +P++   VY          +
Sbjct: 59  KKIFYVANNGAYVG-CHGRCLYAYTMERELAHRIIRKVRMHPEL-EMVYAGVNGDYLDSK 116

Query: 108 DD---EWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAI 164
           DD   +W  N ++   +R       +    +  + + EG+     T D +++    +QA 
Sbjct: 117 DDTLCDWLTNGYKFNVIRVKDVLELEEPCVKISIYKKEGIEAA--TRDIYDEFK--DQAK 172

Query: 165 NARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSM 224
            A  GD           ++ MA  V+KG A+  + + LG  +++ +AFGD +ND EML+ 
Sbjct: 173 MACAGD---------MWMDCMAKDVNKGKAVRTIQESLGIKMEETMAFGDQLNDIEMLNQ 223

Query: 225 AGKGCIMGSAHQRLK 239
           A     + +A + ++
Sbjct: 224 AYYSFAVANAREEVR 238


>UniRef50_A0Q2R8 Cof-like hydrolase n=1 Tax=Clostridium novyi NT RepID=A0Q2R8_CLONN
          Length = 269

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 67/252 (26%), Positives = 117/252 (46%), Gaps = 16/252 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR-------HHVDVGQIR 53
           MY+++A D+DGTLL+ D  +S     T+     RGI     TGR       +  ++G  +
Sbjct: 1   MYKLIAIDMDGTLLNSDKKVSKENIATINEAMKRGIRVAICTGRPYSGIEPYAKEIGLCK 60

Query: 54  DNLEIKSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF 112
           D+     Y+I+ NG+ V +  D   I A  L+ +  + +   + D    +  V   D   
Sbjct: 61  DD----EYIISQNGSYVSNGNDTKTISAKYLNVEETNKILSYLEDKEIGVVLVTDKDYLA 116

Query: 113 MNRHRPEEMRFFKEAVFQ-YALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
            N    EEM+   + VF+   +++     +E   + K+    +SH ++  + + ++    
Sbjct: 117 YNCEINEEMKRDADLVFKTIKMFDKSKDSIENLKLVKIMIMDNSH-KIDNIIENMDKNII 175

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           +   V  S    +E+MA  V KG+ L  +A+ L    KD +  GD +ND  M  +AG G 
Sbjct: 176 NSCYVVRSMPYLIEIMAKNVDKGYGLSKLAEHLNIDHKDIMVIGDELNDIGMFKVAGLGV 235

Query: 230 IMGSAHQRLKDL 241
            M +A+  +K L
Sbjct: 236 AMANANIEIKRL 247


>UniRef50_A9H332 Cof-like hydrolase n=3 Tax=Acetobacteraceae RepID=A9H332_GLUDA
          Length = 273

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 61/238 (25%), Positives = 107/238 (44%), Gaps = 3/238 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V +D+DGTL++ +  L+P A   ++ L  RGI F   +GR  + +  + D L I   +
Sbjct: 10  RLVLADVDGTLVTREKILTPRAIRAVERLRERGIVFTITSGRPPLGMKMVIDPLHIDQPI 69

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRHRPEEM 121
              NG  +   D ++I AH L +D+A     ++ D+  +   VY  ++W + N   P   
Sbjct: 70  AGFNGGMIVRPDYSVIEAHTLTQDVARRTLEILRDH-RVDPWVYNGNDWIVSNAEAPHVA 128

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           R      F   + + G  + + V K+    D  E +  +E  +    GD  + + S    
Sbjct: 129 REQWTVKFPPKVADVG-AQLDQVVKITGVSDDLELMKKVEHDLQQALGDAASAARSQPYY 187

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           ++V     +KG  ++A+ + LG         GD  ND  M   +G    MG A   +K
Sbjct: 188 VDVTHHDANKGGVVKALERLLGIPAAQMATLGDQPNDVLMFVRSGLSIAMGQAIDEVK 245


>UniRef50_Q03GE4 Predicted hydrolase of the HAD superfamily n=2 Tax=Lactobacillales
           RepID=Q03GE4_PEDPA
          Length = 270

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 78/278 (28%), Positives = 128/278 (46%), Gaps = 31/278 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS-- 60
           +++A D+D TLL+ +  L P  K+ +       +  V  +GR    V    + L I +  
Sbjct: 4   KLIAIDVDDTLLNSNIVLLPSTKDIIAKCLQNHLKVVLCSGRPLAGVKPFLNELGITADD 63

Query: 61  -YMITSNGARVHDLDGNLIFAHNLDRDI--ASDLFG----VVNDNPDIITNVYRDDEWFM 113
            Y+IT NG+ +  + G +I +H L   +  A D F     V  +  D  +N+Y  +    
Sbjct: 64  QYVITYNGSVIESVTGEVIASHELSNSVYRAMDEFSRKYHVAYNVLDRDSNIYTSN---- 119

Query: 114 NRHRPEEMRFFKEAVFQYALYEPGLL--EPE------GVSKVFFTCDSHEQLLPLEQAIN 165
                E  RF    V Q    + GLL   P+       ++K  F  ++ E L  +E+A++
Sbjct: 120 ----LEVNRF---TVVQAWENKAGLLIKTPDQLPADFTITKGIFVGETAE-LNQVEEAVH 171

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
           A + D+  V  +    LEVM   V+KG AL+ +++KLG   ++ IAFGD  ND  M    
Sbjct: 172 AAFDDQCYVVRAADNFLEVMHKNVNKGAALKTLSEKLGIHPEEIIAFGDEQNDIPMFDFV 231

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           G    M +     K  H ++ +  +N  D + + L KL
Sbjct: 232 GTAVAMENGSDLAKS-HADM-ITSSNDADGIKNALEKL 267


>UniRef50_D1YD13 Cof-like hydrolase n=3 Tax=Propionibacterium acnes
           RepID=D1YD13_PROAC
          Length = 265

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 83/279 (29%), Positives = 122/279 (43%), Gaps = 32/279 (11%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  ++A+DLDGT L  D   S    E +      G++ VFATGR +  +  +     I  
Sbjct: 1   MIALIATDLDGTFLGADKLPSAENTEAMFAAADAGVHVVFATGRPYRWLTVLDPFRPIHP 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            ++ SNGA   D     +  H+L       + G+V D    + +     E        E 
Sbjct: 61  TLLASNGAVSVDAATGKVL-HDLYM-TPQTVTGIVCDVRQALPHALFCTE--------EA 110

Query: 121 MRFFKEAVF-QYALYEPGLLEPEGVSKV-FFTCDSHE--QLL---------PLEQAINAR 167
            ++F E  F ++ +  P    P+G  ++  F  D H   +LL          L Q +   
Sbjct: 111 TQWFSEEGFDRWQISGP----PDGEGQIESFLGDDHRIVKLLVRTFGFPSDELFQIVKPI 166

Query: 168 WGDRVNVSFS-TLT--CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSM 224
            GDR  V+FS T+T   +E+   G+SKG AL+ V   LG    D  AFGD  ND  ML  
Sbjct: 167 VGDRGTVTFSATMTDGLVEIAGRGISKGSALKQVCDDLGIDPADAAAFGDMPNDLTMLET 226

Query: 225 AGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            G   I+  AH  L+D      +IG + + AV   +R L
Sbjct: 227 VGHPYIVSGAHPVLRDRG--FAIIGNHDESAVGRKVRAL 263


>UniRef50_A7VNH3 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VNH3_9CLOT
          Length = 272

 Score = 75.1 bits (183), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 72/273 (26%), Positives = 125/273 (45%), Gaps = 17/273 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRD-NLEIKS 60
           Y+++A DLDGTL++    ++  AK+ +      G     A+GR    +   +D  L  K 
Sbjct: 3   YRLLALDLDGTLVTSHGGITEAAKQAVWSYIDAGGVVALASGRPTRGLWPAQDLRLAQKG 62

Query: 61  -YMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y+++ NG ++ +   G  I+  ++ +D+   +  ++ D    +  +   D++ +  H  
Sbjct: 63  GYLLSYNGGKIVNCKTGAAIYEKDIPQDLVPVIIRMIRDAG--MEAISYQDQYVLLEH-V 119

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFF------TCDSHEQLLPLEQAINARWGDRV 172
           + + F +EA      Y+     P+  + V F       C + EQ+L LE+      G RV
Sbjct: 120 DRLWFDREASVCRMEYKE---VPDLAAYVTFPVVKLMACGAPEQILALEKQAQEAIGSRV 176

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           +V  S    LE +A G+ K   LE + K LG +     AFGD  ND  M+  AG G  M 
Sbjct: 177 DVFRSEDFYLEFVAKGIDKAATLEVLLKHLGLTRDSLAAFGDSYNDIPMIKYAGFGVAMA 236

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           ++   +  L     V  +N +D V H + +  L
Sbjct: 237 NSIPEV--LQAADAVTKSNDEDGVAHAIYRYLL 267


>UniRef50_Q03T33 Predicted hydrolase of the HAD superfamily n=9 Tax=Lactobacillaceae
           RepID=Q03T33_LACBA
          Length = 271

 Score = 75.1 bits (183), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 73/277 (26%), Positives = 120/277 (43%), Gaps = 24/277 (8%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK--- 59
           +++A D+DGTLL+  + L+    + ++   A+GI  V  TGR    V    D ++I    
Sbjct: 4   KLIAIDIDGTLLNEKNELAQATIDAVQAAKAQGIKVVLCTGRPLTGVQPYLDAMDIDGDD 63

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVN--------DNPDIITNVYRDDEW 111
            Y IT NG+    + G ++  H+L  +   DL             + PD I    +D   
Sbjct: 64  QYAITFNGSVAQTISGKVLTNHSLTYEDYIDLEAWARKVRAHFQIETPDYIYTANKDISA 123

Query: 112 FMNRHRPEEMRFFKEAVFQY--ALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
           +          +    + QY      P  L    +SK  F  D  + +  ++  +   + 
Sbjct: 124 YTIAES-----YLVRMLIQYREVSETPRDLT---ISKAMF-VDYPQVIEQVKANMPQDFK 174

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           DR +V  S    +EVM    SKG  L  +  +LG +  D +  GD  ND  M+  AG G 
Sbjct: 175 DRFSVVQSAPYFIEVMNRRASKGGTLSELVDQLGLTADDVMTLGDQGNDLTMIKYAGLGV 234

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            MG+A   +K+    + +  TNA++ V   +RK  L+
Sbjct: 235 AMGNAIDEVKEAAQAVTL--TNAENGVAAAIRKYALN 269


>UniRef50_UPI0001973D90 HAD family hydrolase n=1 Tax=Clostridium sp. M62/1
           RepID=UPI0001973D90
          Length = 282

 Score = 75.1 bits (183), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 74/253 (29%), Positives = 117/253 (46%), Gaps = 32/253 (12%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V SD+DGTL+  D  +    KE  +LL  +GI F  A+GR    + Q  + L+I   +
Sbjct: 9   RLVVSDVDGTLVGNDCVMEEGMKELSRLLREQGIAFTLASGRPVGMMRQYMEALDITLPV 68

Query: 63  ITSNGARVHDLDGNLIFAHNLD----RDIA--SDLFGV-VNDNPDIITNVYRDDEWFMNR 115
           I SNGA  ++  G  I+   L     R +A  +D  G+ V  N  I   VYR +++   R
Sbjct: 69  IASNGAAGYE-KGAFIWKEILPGRAVRTVAEEADRLGLAVFLNDGITEGVYRQNDY--TR 125

Query: 116 HRPEEMRFFKEAVF-------QYALYEPGLLEPEGVSKVFFTCDSHEQLLP-LEQAINA- 166
            + E+   ++  +           L +  +++P+   +    CD   +LL   E  I   
Sbjct: 126 RQTEKTGLYETVIHPEGDEWETIELQKLMIIDPDSPGR----CDELRELLKERENGIYVV 181

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
           R+ DR         C E M  G SKG  +  +A  LG    + +A GD +ND +M   AG
Sbjct: 182 RYDDR---------CFEAMPEGCSKGSGIRRLADYLGIHPGEILAVGDNINDLDMFEAAG 232

Query: 227 KGCIMGSAHQRLK 239
               +G+A + LK
Sbjct: 233 WSAAVGNAAEELK 245


>UniRef50_Q5XD45 Putative hydrolase M6_Spy0533 n=25 Tax=Streptococcaceae
           RepID=Y533_STRP6
          Length = 269

 Score = 75.1 bits (183), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 75/288 (26%), Positives = 126/288 (43%), Gaps = 46/288 (15%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK--- 59
           ++VA D+DGTLL+ D  ++    + ++   A+G++ V ATGR    V  + + LE+    
Sbjct: 4   KLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATGRPIAGVISLLEQLELNHKG 63

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRD--DEWFMNRHR 117
           +++IT NG  V D +           +I  +L              Y D  +  F++R  
Sbjct: 64  NHVITFNGGLVQDAETG--------EEIVKELM------------TYDDYLETEFLSRKL 103

Query: 118 PEEMR-FFKEAVF-------QYALYEPGLLE-------PEGVSKV----FFTCDSHEQLL 158
              M    KE ++       +Y ++E  L+        PE ++          D  + L 
Sbjct: 104 GVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPDLLD 163

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
              + I   + D+  +  ST   LE M   VSKG+A++ +AKKLG  +   +A GD  ND
Sbjct: 164 AAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIGDAEND 223

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             ML +     +M +    LK +     +  +N D  V H +RK  L+
Sbjct: 224 RAMLEVVANPVVMENGVPELKKIAK--YITKSNNDSGVAHAIRKWVLN 269


>UniRef50_C4FTB9 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FTB9_9FIRM
          Length = 274

 Score = 75.1 bits (183), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 65/253 (25%), Positives = 114/253 (45%), Gaps = 22/253 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           YQ++  D+D TL++ ++T+S    + L     +G   V A+GR    + +    L++   
Sbjct: 4   YQMLVLDIDDTLMTSENTISDATYQALMKAQEQGKKVVLASGRPTPSMIETAKQLKLDHF 63

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR-- 115
            SY+I+ NGA +  + DG  +F+  L+ +   D+   +     +    Y DD   M++  
Sbjct: 64  DSYIISFNGAAITSMADGQELFSQRLEAEAQDDIVRYIQ-AKGLTVLTYMDDYVVMDKAN 122

Query: 116 ---HRPEEM-----RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
              H   ++     R+  EA+   +      ++  GV        +  +L         R
Sbjct: 123 DYSHIESQLTGIPDRYDPEAIANLSQLAKARMKFIGVGDPDLVAAADAEL-------EGR 175

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
           +G+    + S    LE +   VSKG A++ + + LG +L   IA GDG ND  M+  AG 
Sbjct: 176 FGELTYATTSKPYFLEFVHHQVSKGQAIKVLCQHLGLTLDQVIACGDGNNDLTMIETAGL 235

Query: 228 GCIMGSAHQRLKD 240
           G  M +A   LK+
Sbjct: 236 GVAMANATPLLKE 248


>UniRef50_D1PLJ0 Hydrolase n=1 Tax=Subdoligranulum variabile DSM 15176
           RepID=D1PLJ0_9FIRM
          Length = 308

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 64/259 (24%), Positives = 118/259 (45%), Gaps = 38/259 (14%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+V+A DLDGTL + +  ++P  K  L+    RG+  V A+GR  V +  +   LE++ +
Sbjct: 39  YKVLALDLDGTLTNSEKIITPRTKAALQEAARRGVCIVLASGRPTVGIQPLARELELEKF 98

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIAS----------------DLFGVVNDNPDI 101
              +++ NG ++ D   G  +  H    D+                  D  GVV ++ D 
Sbjct: 99  GGCILSYNGGKIIDCKTGKTLVQHAFPPDLIEPVCTFSRYWNVVPLTYDAGGVVTEHAD- 157

Query: 102 ITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLP-L 160
             + Y  +E  +N+    E+      V +Y ++           K+  T D  +  +P +
Sbjct: 158 --SPYVQEEARINKIPVREVPDLPAEV-RYPIH-----------KLLLTGDPAD--MPHV 201

Query: 161 EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAE 220
           E+ +   +  ++++  S    +E M   V K  +L+ + +  G + ++ +A GDG ND  
Sbjct: 202 EELMQQEFAGKLSIYRSQPFFIETMPLNVEKAASLDLLLRSKGLTAENLMACGDGWNDLP 261

Query: 221 MLSMAGKGCIMGSAHQRLK 239
           M+  AG G  MG+A   +K
Sbjct: 262 MIRFAGLGVAMGNAQAPVK 280


>UniRef50_Q02XE2 Predicted hydrolase of the HAD superfamily n=4 Tax=Lactococcus
           lactis RepID=Q02XE2_LACLS
          Length = 278

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 77/271 (28%), Positives = 119/271 (43%), Gaps = 10/271 (3%)

Query: 3   QVVASDLDGTLLSPD-HTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           +++A DLDGT L  D  ++S Y K   K + + G      TGR       +   LE+ S 
Sbjct: 8   KLIAIDLDGTTLQSDGRSISRYTKYIFKQVESLGHIICITTGRPFRMSLDVYRELELTSP 67

Query: 62  MITSNGARV---HDLDGNLIFAHNLDRDIASDLFG-VVNDNPDIITNVYRDDEWFMNRHR 117
           +I  NGA +   +D +     ++ +DR    DL     N N       YR  ++F+N  R
Sbjct: 68  VINFNGALISMPNDKNWEHTKSYYIDRSFIFDLLRHQQNFNLHFFAVEYRR-KFFLNTFR 126

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF- 176
             E + F    FQ           E    V  +    ++L  L + +   +  +++V   
Sbjct: 127 NVEPKLFGVEKFQPYNRLRADRVTENPHAVLLSTRQKDKL-GLAEEMKRHYNGKIDVGVW 185

Query: 177 -STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
                 LEV+  G+SK   L  + K L   L++ IAFGD  ND EM  +A +   M +A 
Sbjct: 186 GGPNGILEVVPKGISKASGLNHLLKVLDIPLENLIAFGDEHNDIEMFKLAPQAYAMKNAS 245

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            RL     E+ +  TN +D V   L KL+L+
Sbjct: 246 ARLTPYASEI-LPWTNDEDGVARQLEKLFLT 275


>UniRef50_Q5WF79 HAD superfamily hydrolase n=4 Tax=Bacillaceae RepID=Q5WF79_BACSK
          Length = 257

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 63/235 (26%), Positives = 104/235 (44%), Gaps = 14/235 (5%)

Query: 8   DLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNG 67
           D+DGTLL  +  L    K+ +  L  +G     ATGR      ++R+ LEI SY I  NG
Sbjct: 9   DIDGTLLDEEKRLPQSTKQAIAALKEKGHEVAIATGRAPYFFKELREELEIDSY-ICFNG 67

Query: 68  ARVHDLDGNLIFAHNLDRDIASDL--FGVVNDNPDIITNVYRDDEWFMNRH-RPEEMRFF 124
             V    G LI+ + LD D  +++  +    ++P +         +  NR   P  ++  
Sbjct: 68  QYV-VFKGELIYENTLDMDAFTEMERYASSQEHPLVFMG---SKTYTSNREDHPYVIKSI 123

Query: 125 KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEV 184
           K        Y P L   + + +    C+  E     E+    R+     V +  L+ ++V
Sbjct: 124 KTLKIDLPQYNPDLYNEQPLHQALLFCEEGE-----EKDYETRFPALRFVRWHPLS-VDV 177

Query: 185 MAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           +    SK + +    ++    L +  AFGD +ND EMLS    G  MG+A +++K
Sbjct: 178 LPREGSKANGIAKFIQRANIDLANVYAFGDQLNDLEMLSFVEHGVAMGNAPEKVK 232


>UniRef50_C9XLD9 Putative hydrolase n=7 Tax=Clostridium difficile RepID=C9XLD9_CLODC
          Length = 273

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 67/281 (23%), Positives = 124/281 (44%), Gaps = 26/281 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGT+L+    ++P   E+++     G   V  TGR    V ++ + L +  
Sbjct: 1   MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGRPLPGVKELLNQLNLTD 60

Query: 61  ---YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y+I  NGA + ++             I  D+   ++D   I  NV +  +  ++ + 
Sbjct: 61  EGDYVICFNGAIIQEVKS---------EKIIHDVEMTLDDFDFIYNNVCKKYKTKIHINT 111

Query: 118 PEEMRFFKEAVFQYALYEPGL-------LEPEGVSKVFFTC-----DSHEQLLPLEQAIN 165
              +    EA  +Y L+E  L       ++ + + +    C     D  E+L  + Q + 
Sbjct: 112 MTNLITPNEAPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEPERLEEIIQQLP 171

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
               ++  +  S    LE +    +KG AL+ +   L   +++ IA GD  ND  M+  A
Sbjct: 172 KNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAVGDEENDQHMIKYA 231

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           G G  MG+A   +K++     V  TN ++ V   + K  L+
Sbjct: 232 GLGVAMGNARNSIKEIAD--YVTDTNNENGVAKVINKYILN 270


>UniRef50_C2V4H7 Cof-like hydrolase n=5 Tax=Bacillus cereus RepID=C2V4H7_BACCE
          Length = 267

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 66/268 (24%), Positives = 123/268 (45%), Gaps = 12/268 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           +++V  DLDGTLL+ +  +S    +T++ L    I  + AT R   D+      LE+ + 
Sbjct: 5   FEIVICDLDGTLLNNNKEISNKTVKTIQSLNQMKIPVILATARAPRDIEIYLKGLELDTP 64

Query: 62  MITSNGARVHDLDGNLIFAHNL-DRDIASDLFGVVNDNPDIITNVY-RDDEWFMNRHRPE 119
            I  NGA + D   + I   N+ D  I   LF V+ +   I   +  +++E++++    +
Sbjct: 65  SICYNGALIFDNRNSKILTSNMIDISIVKKLFEVLREEKSIENYLAEKNNEFWVDVIDKD 124

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF--S 177
              +       +A+  P     + +SK+    ++   +  LE+     + + +  +F  S
Sbjct: 125 VQCWIDAGCPPHAIGYPSTFLDDHLSKLIVRGNTEFIIRILEK----HFKEHLIYTFSDS 180

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               +E++     K  A++ +A      L + +AFGD  ND  ML + G G  MG++   
Sbjct: 181 RKVWIEILCKNAGKAAAVKWIANHYSVPLSNIVAFGDAENDIGMLELVGFGVAMGNSG-- 238

Query: 238 LKDLHPELEVIG-TNADDAVPHYLRKLY 264
            KD+  +   I  TN +D V H L  ++
Sbjct: 239 -KDVQLKANCIAPTNENDGVAHTLHGIF 265


>UniRef50_UPI000197CA00 hypothetical protein PretD1_00540 n=1 Tax=Providencia rettgeri DSM
           1131 RepID=UPI000197CA00
          Length = 270

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 75/271 (27%), Positives = 122/271 (45%), Gaps = 17/271 (6%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS-- 60
           ++VA DLDGTLL+  H +SP  KE +     +G++ + A+GR    +      L++ +  
Sbjct: 4   KLVAIDLDGTLLNSQHQISPVVKEAITQAKQKGVHIILASGRPFSGISPYLRELDLNTAD 63

Query: 61  -YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRHRP 118
            Y I++NG+ +H  +     A NL        F  +  N  +  +   D+  F  NRH  
Sbjct: 64  NYCISNNGSVIHQANDGSHLAENLLDFADFQYFEELARNVGVHMHALADNSMFTANRH-- 121

Query: 119 EEMRFFKEAVFQYALYEPGLLEP--EGVSKVFFT----CDSHEQLLPLEQAINARWGDRV 172
             +  +  A   Y  + P +  P  E  S + FT     D  E+L      I     D  
Sbjct: 122 --ISHYTVAD-AYLTHTPLIYCPVNEMDSSLEFTKFMIIDHPEKLDMGISYIPENVFDNY 178

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           +++ ++   LEV     SKG ALE + +KLG +    ++ GD  ND +ML  A     MG
Sbjct: 179 SLTRTSPYFLEVSNKTSSKGAALECICEKLGITPDKVMSIGDQNNDIQMLQYASVSVAMG 238

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           +A + ++ +     V  TN +D V   + K 
Sbjct: 239 NALEPIRQMVK--FVTTTNDEDGVAVAINKF 267


>UniRef50_Q6KIP5 COF family HAD hydrolase protein n=1 Tax=Mycoplasma mobile
           RepID=Q6KIP5_MYCMO
          Length = 270

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 73/275 (26%), Positives = 120/275 (43%), Gaps = 21/275 (7%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++ A DLDGTLL     + P  K+ L L   +G   + ATGR    V    + +    Y+
Sbjct: 2   KIFAFDLDGTLLEDSGEIHPGTKKVLDLAVKKGHKLILATGRGLSAVLPFLEKVSGIEYL 61

Query: 63  ITSNGARVHDLDGNLIFA-HNLDRDIASDLFGVVNDNPDI------ITNVYRDDEWFMNR 115
           I SNG+ + D+  + +     L+ D+  D      +N +I      I N++      +N 
Sbjct: 62  ICSNGSVLFDVKNSKVKNLKPLEMDVYEDFVQEAKNNENIFFSANGIQNIF-----VINT 116

Query: 116 HRPEEMRF----FKEAVFQYALYEPGLLEPEGVSKVFFTC--DSHEQLLP-LEQAINARW 168
             P E ++     KE +      E      +    VF      S E  +  L +    ++
Sbjct: 117 FPPLEEKYDQNYIKELLKGTIPVEDEYAREKLEEDVFIQAALKSDEITIKHLYEKYREKY 176

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
           GD+ ++  +    L++     SK +AL    K +  +  D I+FGD  ND +M+  + KG
Sbjct: 177 GDKYSIVITNKVYLDINPLNASKYNALIVALKNMNKNEGDLISFGDSNNDLDMVKNSSKG 236

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
             M  A ++LK +    EVIGTN  D +   L +L
Sbjct: 237 YAMQHATEQLKKVAT--EVIGTNNSDTIGKKLLEL 269


>UniRef50_Q0TU23 HAD-superfamily hydrolase, subfamily IIB n=7 Tax=Clostridium
           perfringens RepID=Q0TU23_CLOP1
          Length = 274

 Score = 74.7 bits (182), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 72/287 (25%), Positives = 123/287 (42%), Gaps = 40/287 (13%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  D+DGTLL     ++   K  +K    +G      TGR +       D + +K+ +
Sbjct: 4   KLICIDMDGTLLMDQQNIAEEDKNAIKEAVKKGAIVAITTGRIYDCARMYSDTIGLKTPI 63

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASD---------LFGVVNDNPDIITNV-------Y 106
           I SNGA +  ++   I+ + L +    D         LF  V  N  I++ V       Y
Sbjct: 64  IASNGAYIGGVNDEEIYNNPLKQSDLEDFNIITKKNNLFTYVTTNWGIVSTVELPENHVY 123

Query: 107 RDDEWFMNRHRPEEMRFFKEAVFQ----YALYEPGLLEPEGVSKVFFTC--DSHEQLLPL 160
           +     +N+  P++ +   E V      +  Y+  +L+   V K F     ++ E+L+  
Sbjct: 124 K----VLNKTLPKDKQVRLEVVKDLDEAFKKYKGEILKGVCVEKEFKDKLKEAKEELIAC 179

Query: 161 --EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
             +  + + W D            E+M  G SKG A++ +AK LG S ++ +  GD  ND
Sbjct: 180 TTDLEVVSSWDDN----------FEIMKKGSSKGEAVQMLAKYLGVSQEEVMCIGDSEND 229

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             M++ AG G  MG+A   +K+      V   N    V   +RK  L
Sbjct: 230 LSMITWAGTGVAMGNAIDSVKEFAN--YVTSDNKHGGVAEAIRKFVL 274


>UniRef50_A6LB33 Haloacid dehalogenase-like hydrolase n=34 Tax=Bacteria
           RepID=A6LB33_PARD8
          Length = 410

 Score = 74.3 bits (181), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 65/249 (26%), Positives = 109/249 (43%), Gaps = 17/249 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+    ++P     L      G++ V A+GR    V  + + LE+  Y
Sbjct: 3   YKLLVLDVDGTLLNDKKEITPRTHAALLKAQQMGVHVVLASGRPTNGVQPLAEALELNHY 62

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRD---DEWFMN 114
              +++ NG ++ +   G L+F   +D  +   L     +N   I   ++D    +   N
Sbjct: 63  GGFILSYNGGQIINAQTGELMFEKRIDPAMIPYLNRKAKENGFAIFTYHKDYILTDSPEN 122

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPEGV----SKVFFTCDSHEQLLPLEQAINARWGD 170
           +H  EE    K  +     +      PE V     K   T D    L+ LE     R   
Sbjct: 123 KHVQEEAELNKMRIIGVENF------PEAVDFAPCKCILTSDDENNLVGLENHWKKRLDG 176

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            +    S    LEV    ++KG+ L  + + L  + ++ +A GDG+ D  ML +AG G  
Sbjct: 177 VLEAFRSEDYFLEVAPHFINKGNTLAVLMEMLNITTEEVVAIGDGVADVSMLQLAGTGVA 236

Query: 231 MGSAHQRLK 239
           MG+A   +K
Sbjct: 237 MGNARDSVK 245


>UniRef50_D0BJQ5 Cof family protein n=2 Tax=Granulicatella RepID=D0BJQ5_9LACT
          Length = 271

 Score = 74.3 bits (181), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 67/268 (25%), Positives = 117/268 (43%), Gaps = 10/268 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGT L+     +P   +TL  LT  G      TGR +     + + L +   +
Sbjct: 4   KLIALDLDGTTLNGQSEFNPITIQTLHRLTELGHKIAIVTGRPYRSSKHLYEELGLGGPL 63

Query: 63  ITSNGARVH---DLDGNLIFAHNLDRDIASDLFGVVND-NPDIITNVYRDDEWFMNRHRP 118
           +  NGA  H   D +    F   LD +I  D+     +   D      +   +    + P
Sbjct: 64  VNFNGALCHIPNDENWQGEFHVTLDEEIVFDMLDFHKELECDYFMVEGKHHLYATIENIP 123

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF-- 176
           +   + K+        +  LLE      VF    S E+   +++ I  R+G  ++V    
Sbjct: 124 DSPYYPKDQQPILLQKDTQLLEKPTAITVF---SSIEKQPFIKEKIKQRYGHTIDVRTWG 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
             + CLE++  G+ K   ++ +++  G   +D +AFGD  ND EM+  AG G  M +A  
Sbjct: 181 GDMPCLEIVTYGIDKSTGIQHLSRYYGIPTEDVLAFGDEDNDLEMIEFAGHGVAMNNAID 240

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            LK +  ++  +  +  D + HYL   +
Sbjct: 241 SLKAIADDITPL-PHDQDGLAHYLMNYF 267


>UniRef50_C8PSD2 Hydrolase n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PSD2_9SPIO
          Length = 273

 Score = 74.3 bits (181), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 67/258 (25%), Positives = 119/258 (46%), Gaps = 21/258 (8%)

Query: 20  LSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL---EIKSYMITSNGARVHDLDGN 76
           +S Y    L+ L  +G+  + A+GR    V      +   + +SY++ +NG ++   D  
Sbjct: 25  ISDYTVSVLQALMKKGVLTLLASGRSPRSVHSYAQRIGSDKTESYILCNNGTQILTSDMK 84

Query: 77  L-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYE 135
           L I +  L  D+A +++  + ++ ++  ++Y DD  ++ RH     R          L +
Sbjct: 85  LEIISRCLGADLALEIYDYI-ESQNLSCHLYLDDTIYIVRHTVFSDR-------DAHLTK 136

Query: 136 PGLLEPEGVSKVFFTCDSHEQLLPLEQAINA--------RWGDRVNVSFSTLTCLEVMAG 187
             ++ P+   ++  T   ++ L+P E  I A        R+G R  +  S    LE++  
Sbjct: 137 MKIVVPKDYREILRTKPVYKLLIPAEPDIIAAVEPEFRKRFGTRAVLFTSKPYFLEIIPL 196

Query: 188 GVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEV 247
              KG  L+ +A  LG   K  +AFGD MND  M+  AG G  M +    +KD+   +  
Sbjct: 197 DTGKGEFLQELAWLLGIRDKAVMAFGDSMNDETMIRYAGYGIAMKNGLDAIKDIAYAVTE 256

Query: 248 IGTNADDAVPHYLRKLYL 265
             TN +D + H+L K  L
Sbjct: 257 Y-TNNEDGIAHFLEKYVL 273


>UniRef50_Q0SUS9 Cof-like hydrolase, HAD-superfamily, subfamily IIB n=9
           Tax=Clostridium perfringens RepID=Q0SUS9_CLOPS
          Length = 279

 Score = 74.3 bits (181), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 70/280 (25%), Positives = 127/280 (45%), Gaps = 33/280 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++  SDLDGTLL+ D  +S Y+K+ L  L + G+NF  AT R    V  I + ++IK+ +
Sbjct: 2   ELFVSDLDGTLLNKDQVISDYSKKELNRLISTGVNFAIATARSPATVLDILNGIDIKTPV 61

Query: 63  ITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVND----------NPDIITNVYRDDEW 111
           +  NG  + D++    I    +D++   ++  ++              D +   ++D  +
Sbjct: 62  VLMNGVIIFDIEKKKYIDVKEIDKESVKEIIKILKKYNKTFFLYGIKDDYLWVYHKDFTY 121

Query: 112 FMNRHRPEE-----MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDS------HEQLLPL 160
              R   EE     ++ FK+       Y   L + + ++ VFF  +        E+++ +
Sbjct: 122 DFERKYYEERCNKKLKSFKKV----ENYLDILNDNQIINFVFFEDNKLIAHELFEKIMKV 177

Query: 161 EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAE 220
           +      + D  N        L+V     SK + ++ +A  + +S    I FGDG ND  
Sbjct: 178 KGVTGNCYKDIYN---EGAFFLDVYNEEASKANGIKFLADYVEHS--KVITFGDGENDIP 232

Query: 221 MLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
           M  ++ +   + ++ Q LK +     VIG N DDAV  +L
Sbjct: 233 MFKISDECYALENSSQELKSIST--GVIGNNNDDAVVKFL 270


>UniRef50_Q04BG8 Predicted hydrolase of the HAD superfamily n=13 Tax=Lactobacillus
           RepID=Q04BG8_LACDB
          Length = 294

 Score = 74.3 bits (181), Expect = 4e-12,   Method: Compositional matrix adjust.
 Identities = 78/292 (26%), Positives = 115/292 (39%), Gaps = 37/292 (12%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++  DLDGTLL+    +S    + +K     GI F+ A+GR   +   +     I  
Sbjct: 1   MIKLITCDLDGTLLNSSMEISDANVQAIKRAQENGIEFMVASGRAPHESQPMLKEYWIDC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDL----------FGVVNDN-------PDIIT 103
             I  NG  V D  GNLI  + L  + A  +          F +V  N          IT
Sbjct: 61  SFINLNGGLVFDTAGNLIVKNPLKLETAKKICRLLKKEGFYFELVTSNHVYSEDLSQRIT 120

Query: 104 NVYRDDEWFMNRHRPEEMRFFKEAVF------------QYALYEPGLLEPEGVSKVFFTC 151
           NV       M    P  M  FKEAV             Q   YE  + EP          
Sbjct: 121 NVAH----LMVELNP--MLTFKEAVLVSASKPAIVSIQQVPSYEDLMDEPGTEVMKILVF 174

Query: 152 DSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIA 211
           DS  Q    +        D+++++ S    +E+ A    KG +L   A   G   ++  A
Sbjct: 175 DSRGQYAFTDVIKKIEEIDKLSITSSAADNIEINAASAQKGQSLLDYAAAKGIKREEIAA 234

Query: 212 FGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            GD +ND  M+  AG G  MG+A  ++K +     V  +N +D V   + K+
Sbjct: 235 IGDNLNDESMIQAAGTGVAMGNAVPQIKTIAS--FVTKSNNEDGVAWAIDKI 284


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_P27848 Uncharacterized protein yigL n=168 Tax=Bacteria ...   390   e-107
UniRef50_A0KR21 Hydrolase, Cof family n=3 Tax=Aeromonadaceae Rep...   318   1e-85
UniRef50_Q7MQB3 Predicted hydrolase n=59 Tax=Gammaproteobacteria...   299   8e-80
UniRef50_C6JR95 Hydrolase n=2 Tax=Fusobacterium RepID=C6JR95_FUSVA    286   6e-76
UniRef50_C3WDD5 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC ...   284   2e-75
UniRef50_A8GAR8 HMP-PP phosphatase n=39 Tax=Enterobacteriaceae R...   280   4e-74
UniRef50_A6FJC9 Putative uncharacterized protein n=1 Tax=Moritel...   278   1e-73
UniRef50_C3WN06 Hydrolase n=12 Tax=Fusobacterium RepID=C3WN06_9FUSO   276   5e-73
UniRef50_A1HSX6 Cof-like hydrolase n=1 Tax=Thermosinus carboxydi...   273   5e-72
UniRef50_A1V919 HAD hydrolase, IIB family n=56 Tax=Betaproteobac...   272   6e-72
UniRef50_Q8KA73 Uncharacterized protein BUsg_029 n=5 Tax=Buchner...   268   1e-70
UniRef50_P44771 Uncharacterized protein HI0597 n=32 Tax=Pasteure...   267   2e-70
UniRef50_Q4D2M6 Haloacid dehalogenase-like hydrolase, putative n...   266   4e-70
UniRef50_Q0B097 Putative uncharacterized protein n=1 Tax=Syntrop...   265   1e-69
UniRef50_Q2RLU7 HAD-superfamily hydrolase subfamily IIB n=1 Tax=...   263   4e-69
UniRef50_C6CW76 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CW...   263   5e-69
UniRef50_C9KQV0 HAD-superfamily hydrolase, subfamily IIB n=2 Tax...   261   2e-68
UniRef50_C6AQ91 Cof protein n=4 Tax=Bacteria RepID=C6AQ91_AGGAN       259   1e-67
UniRef50_A6T5I9 HMP-PP phosphatase n=18 Tax=Bacteria RepID=COF_K...   258   1e-67
UniRef50_D0A841 Haloacid dehalogenase-like hydrolase, putative n...   257   2e-67
UniRef50_C2KV90 HAD superfamily hydrolase n=1 Tax=Oribacterium s...   257   3e-67
UniRef50_Q3AFE4 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...   256   7e-67
UniRef50_C3WDI3 Hydrolase n=2 Tax=Fusobacterium mortiferum ATCC ...   256   8e-67
UniRef50_B8I4P5 Cof-like hydrolase n=2 Tax=Clostridium RepID=B8I...   255   9e-67
UniRef50_D1AJW8 Cof-like hydrolase n=1 Tax=Sebaldella termitidis...   254   2e-66
UniRef50_P54947 Uncharacterized protein yxeH n=10 Tax=Firmicutes...   254   2e-66
UniRef50_B8DEX6 Phosphatase YidA n=17 Tax=Listeria RepID=B8DEX6_...   254   3e-66
UniRef50_A4XJ23 Cof-like hydrolase n=2 Tax=Clostridia RepID=A4XJ...   253   4e-66
UniRef50_Q4Q8C9 Haloacid dehalogenase-like hydrolase, putative n...   252   7e-66
UniRef50_Q897B3 Putative haloacid dehalogenase-like hydrolase n=...   252   9e-66
UniRef50_A5FGB8 Cof-like hydrolase n=1 Tax=Flavobacterium johnso...   252   1e-65
UniRef50_A8U9P8 Hydrolase, haloacid dehalogenase-like family pro...   252   1e-65
UniRef50_D1AMP5 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepI...   251   1e-65
UniRef50_B0K874 Cof-like hydrolase n=10 Tax=Thermoanaerobacterac...   251   2e-65
UniRef50_B0K375 Cof-like hydrolase n=11 Tax=Thermoanaerobacteral...   250   4e-65
UniRef50_A7ZIK4 HMP-PP phosphatase n=87 Tax=Bacteria RepID=COF_E...   250   4e-65
UniRef50_C6P8T7 Cof-like hydrolase n=1 Tax=Thermoanaerobacterium...   249   6e-65
UniRef50_C3K9U8 Putative haloacid dehalogenase-like hydrolase n=...   249   8e-65
UniRef50_C1QE38 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...   249   8e-65
UniRef50_C2EBE1 HAD superfamily hydrolase n=1 Tax=Lactobacillus ...   248   1e-64
UniRef50_Q2JQT8 HAD hydrolase, IIB family n=1 Tax=Synechococcus ...   247   2e-64
UniRef50_C4FT61 Putative uncharacterized protein n=1 Tax=Catonel...   247   3e-64
UniRef50_C3WAR4 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC ...   247   3e-64
UniRef50_A6LB32 Haloacid dehalogenase-like hydrolase n=23 Tax=Ba...   246   4e-64
UniRef50_A1SZR3 Cof-like hydrolase n=2 Tax=Psychromonas RepID=A1...   246   8e-64
UniRef50_D0BNB6 Phosphatase YidA n=2 Tax=Granulicatella RepID=D0...   246   9e-64
UniRef50_B0ADP8 Putative uncharacterized protein n=1 Tax=Clostri...   246   9e-64
UniRef50_C9R7C9 Cof protein n=1 Tax=Aggregatibacter actinomycete...   245   9e-64
UniRef50_B1L8F5 Cof-like hydrolase n=6 Tax=Thermotogaceae RepID=...   245   1e-63
UniRef50_Q1QY75 Cof protein n=1 Tax=Chromohalobacter salexigens ...   245   1e-63
UniRef50_C6PXU7 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...   245   1e-63
UniRef50_C2H930 Haloacid dehalogenase (HAD) superfamily hydrolas...   244   2e-63
UniRef50_B8FYX3 Cof-like hydrolase n=2 Tax=Desulfitobacterium ha...   244   2e-63
UniRef50_A0AEX0 Complete genome n=17 Tax=Listeria RepID=A0AEX0_L...   244   2e-63
UniRef50_Q38V42 Hydrolase, haloacid dehalogenase family n=2 Tax=...   244   3e-63
UniRef50_C5WIM4 HAD superfamily hydrolase n=3 Tax=Streptococcus ...   244   3e-63
UniRef50_B8CYJ2 Cof-like hydrolase n=1 Tax=Halothermothrix oreni...   244   3e-63
UniRef50_Q7NXV0 Putative uncharacterized protein n=1 Tax=Chromob...   244   3e-63
UniRef50_P0A8Y6 Phosphatase yidA n=235 Tax=cellular organisms Re...   244   3e-63
UniRef50_C6JK34 Hydrolase n=2 Tax=Fusobacterium RepID=C6JK34_FUSVA    243   4e-63
UniRef50_Q5XD45 Putative hydrolase M6_Spy0533 n=25 Tax=Streptoco...   242   7e-63
UniRef50_B9DT57 Putative haloacid dehalogenase-like hydrolase n=...   242   9e-63
UniRef50_C9LAG7 HAD hydrolase, IIB family n=1 Tax=Blautia hansen...   242   1e-62
UniRef50_A6LB33 Haloacid dehalogenase-like hydrolase n=34 Tax=Ba...   242   1e-62
UniRef50_C6K3T2 Haloacid dehalogenase-like hydrolase-like protei...   241   2e-62
UniRef50_A4BEF7 Hydrolase, haloacid dehalogenase-like family pro...   241   2e-62
UniRef50_Q8ENE7 Hypothetical conserved protein n=1 Tax=Oceanobac...   240   3e-62
UniRef50_Q0TQ35 HAD hydrolase, IIB family n=9 Tax=Clostridium pe...   240   4e-62
UniRef50_C7N949 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7...   239   6e-62
UniRef50_Q04GT8 Predicted hydrolase of the HAD superfamily n=2 T...   239   6e-62
UniRef50_Q891C8 Hydrolase (HAD superfamily) n=3 Tax=Bacteria Rep...   239   7e-62
UniRef50_C7NEL2 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7...   239   7e-62
UniRef50_B0P090 Putative uncharacterized protein n=2 Tax=Clostri...   239   7e-62
UniRef50_C9XMM6 Putative hydrolase n=4 Tax=Clostridium difficile...   239   7e-62
UniRef50_A9H329 Cof-like hydrolase n=1 Tax=Gluconacetobacter dia...   239   1e-61
UniRef50_B0BRY2 Predicted hydrolases of the HAD superfamily n=7 ...   238   1e-61
UniRef50_A8UBX5 Putative uncharacterized protein n=1 Tax=Carnoba...   238   1e-61
UniRef50_A8MEY7 Cof-like hydrolase n=2 Tax=Alkaliphilus RepID=A8...   238   2e-61
UniRef50_C6PMT7 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...   238   2e-61
UniRef50_C7HV82 HAD phosphatase superfamily protein n=1 Tax=Anae...   237   2e-61
UniRef50_C6JKA3 HAD-superfamily hydrolase subfamily IIB n=3 Tax=...   237   2e-61
UniRef50_Q1JAD8 Hydrolase n=30 Tax=Streptococcus RepID=Q1JAD8_STRPB   237   2e-61
UniRef50_C1I280 HAD hydrolase n=1 Tax=Clostridium sp. 7_2_43FAA ...   237   3e-61
UniRef50_A4HGI1 Putative uncharacterized protein n=4 Tax=Leishma...   237   3e-61
UniRef50_UPI000197CA00 hypothetical protein PretD1_00540 n=1 Tax...   237   3e-61
UniRef50_C7JF38 Hydrolase n=8 Tax=Acetobacter pasteurianus RepID...   237   3e-61
UniRef50_C6CYC3 Cof-like hydrolase n=1 Tax=Paenibacillus sp. JDR...   236   4e-61
UniRef50_A4HGI8 Haloacid dehalogenase-like hydrolase-like protei...   236   5e-61
UniRef50_Q03T33 Predicted hydrolase of the HAD superfamily n=9 T...   236   5e-61
UniRef50_Q4KBY5 Cof-like hydrolase family protein n=8 Tax=Pseudo...   236   5e-61
UniRef50_B2A708 Cof-like hydrolase n=1 Tax=Natranaerobius thermo...   236   5e-61
UniRef50_C9XLD9 Putative hydrolase n=7 Tax=Clostridium difficile...   236   7e-61
UniRef50_C4RHE6 HAD-superfamily hydrolase, subfamily IIB n=2 Tax...   236   7e-61
UniRef50_Q1WS49 Hydrolase, HAD superfamily n=2 Tax=Lactobacillus...   236   8e-61
UniRef50_UPI000196CFC2 hypothetical protein CATMIT_02842 n=1 Tax...   236   9e-61
UniRef50_P94592 Uncharacterized phosphatase ywpJ n=7 Tax=Bacilla...   235   1e-60
UniRef50_C9KQH1 HAD phosphatase family protein n=2 Tax=Clostridi...   235   1e-60
UniRef50_Q7N6X1 Similar to unknown protein n=2 Tax=Photorhabdus ...   235   1e-60
UniRef50_C5RPZ1 Cof-like hydrolase n=1 Tax=Clostridium cellulovo...   234   2e-60
UniRef50_Q4DMD3 Haloacid dehalogenase hydrolase, putative n=2 Ta...   234   2e-60
UniRef50_C0Z8L2 Putative uncharacterized protein n=1 Tax=Breviba...   234   2e-60
UniRef50_P44447 Uncharacterized protein HI0003 n=16 Tax=Haemophi...   234   2e-60
UniRef50_C9LXL5 HAD-superfamily hydrolase, family protein IIB n=...   234   2e-60
UniRef50_UPI0001BC341D haloacid dehalogenase-like hydrolase n=1 ...   234   2e-60
UniRef50_Q384S8 Haloacid dehalogenase hydrolase, putative n=3 Ta...   234   3e-60
UniRef50_B1BZI7 Putative uncharacterized protein n=2 Tax=Clostri...   234   3e-60
UniRef50_A6LQL6 Cof-like hydrolase n=1 Tax=Clostridium beijerinc...   234   3e-60
UniRef50_C2BEV0 HAD superfamily hydrolase n=1 Tax=Anaerococcus l...   234   3e-60
UniRef50_D1PLJ0 Hydrolase n=1 Tax=Subdoligranulum variabile DSM ...   233   4e-60
UniRef50_B8DIC3 Hydrolase, Cof family n=18 Tax=Listeria RepID=B8...   233   5e-60
UniRef50_A0Q2R8 Cof-like hydrolase n=1 Tax=Clostridium novyi NT ...   233   5e-60
UniRef50_A5Z5X7 Putative uncharacterized protein n=1 Tax=Eubacte...   232   6e-60
UniRef50_A3MZH9 Predicted hydrolases of the HAD superfamily n=9 ...   232   7e-60
UniRef50_C6QV31 Cof-like hydrolase n=1 Tax=Geobacillus sp. Y4.1M...   232   8e-60
UniRef50_D1AIM0 Cof-like hydrolase n=1 Tax=Sebaldella termitidis...   232   9e-60
UniRef50_B7HYF7 Hydrolase, haloacid dehalogenase-like family n=8...   232   1e-59
UniRef50_A9KKJ5 Cof-like hydrolase n=3 Tax=Clostridiales RepID=A...   232   1e-59
UniRef50_A3I239 Putative uncharacterized protein n=1 Tax=Algorip...   232   1e-59
UniRef50_D1XVB8 Cof-like hydrolase n=1 Tax=Prevotella bivia JCVI...   232   1e-59
UniRef50_Q3D5Y9 Hydrolase, haloacid dehalogenase-like family n=9...   232   1e-59
UniRef50_C2EN69 HAD family hydrolase n=7 Tax=Firmicutes RepID=C2...   231   1e-59
UniRef50_Q97ES2 HAD superfamily hydrolase n=1 Tax=Clostridium ac...   231   2e-59
UniRef50_C5NXD6 Phosphatase YidA n=1 Tax=Gemella haemolysans ATC...   231   2e-59
UniRef50_Q030F1 Predicted hydrolase of the HAD superfamily n=34 ...   231   2e-59
UniRef50_C1P6V3 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36...   231   2e-59
UniRef50_A4VVF4 Predicted hydrolase of the HAD superfamily n=38 ...   231   2e-59
UniRef50_B5CTA9 Putative uncharacterized protein n=4 Tax=Clostri...   231   2e-59
UniRef50_C2LPY8 HAD-superfamily hydrolase, subfamily IIB n=5 Tax...   230   3e-59
UniRef50_A5KNX9 Putative uncharacterized protein n=8 Tax=Clostri...   230   3e-59
UniRef50_Q5WG82 HAD superfamily hydrolase n=1 Tax=Bacillus claus...   230   4e-59
UniRef50_C5EF13 Putative uncharacterized protein n=2 Tax=Clostri...   230   4e-59
UniRef50_C7RFK7 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7...   230   4e-59
UniRef50_C4IB07 Cof protein n=1 Tax=Clostridium butyricum E4 str...   229   6e-59
UniRef50_A0R0M1 Cof protein n=3 Tax=Bacteria RepID=A0R0M1_MYCS2       229   6e-59
UniRef50_B9CKY2 Phosphatase YidA n=1 Tax=Atopobium rimae ATCC 49...   229   8e-59
UniRef50_C0R158 Putative hydrolase n=1 Tax=Brachyspira hyodysent...   229   8e-59
UniRef50_C0X6C9 HAD superfamily hydrolase n=22 Tax=Enterococcus ...   229   8e-59
UniRef50_UPI000196AEDD hypothetical protein CATMIT_00603 n=1 Tax...   229   1e-58
UniRef50_D0BM40 Cof family protein n=2 Tax=Granulicatella RepID=...   228   1e-58
UniRef50_C7ND82 Cof-like hydrolase n=4 Tax=Leptotrichia RepID=C7...   228   1e-58
UniRef50_B0P1S7 Putative uncharacterized protein n=2 Tax=Clostri...   228   2e-58
UniRef50_A5CYL3 Predicted hydrolase n=5 Tax=Clostridia RepID=A5C...   228   2e-58
UniRef50_A8HYJ4 Haloacid dehalogenase-like hydrolase n=1 Tax=Chl...   228   2e-58
UniRef50_A0M3X3 Haloacid dehalogenase-like hydrolase n=2 Tax=Fla...   227   2e-58
UniRef50_Q8RF49 Hydrolase (HAD superfamily) n=10 Tax=Fusobacteri...   227   2e-58
UniRef50_B7GIB3 Predicted hydrolase of the HAD superfamily n=3 T...   227   3e-58
UniRef50_D1AWH0 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepI...   227   3e-58
UniRef50_C9LXL4 HAD hydrolase, IIB family n=1 Tax=Selenomonas sp...   227   4e-58
UniRef50_A9BES4 Cof-like hydrolase n=1 Tax=Petrotoga mobilis SJ9...   227   4e-58
UniRef50_C8RSV0 HAD family hydrolase n=2 Tax=Corynebacterium jei...   227   4e-58
UniRef50_B2GFE5 Hydrolase n=12 Tax=Lactobacillus RepID=B2GFE5_LACF3   227   4e-58
UniRef50_B0N4M8 Putative uncharacterized protein n=3 Tax=Bacteri...   226   5e-58
UniRef50_B2IW20 Cof-like hydrolase n=18 Tax=Cyanobacteria RepID=...   226   6e-58
UniRef50_Q034C6 Predicted hydrolase of the HAD superfamily n=8 T...   226   6e-58
UniRef50_C4V675 HAD superfamily hydrolase n=1 Tax=Selenomonas fl...   226   6e-58
UniRef50_Q0TU23 HAD-superfamily hydrolase, subfamily IIB n=7 Tax...   226   6e-58
UniRef50_Q819K1 Hydrolase (HAD superfamily) n=77 Tax=Bacillaceae...   226   7e-58
UniRef50_C7RDZ8 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7...   226   7e-58
UniRef50_Q5FQA0 Putative hydrolase of the HAD superfamily n=1 Ta...   225   8e-58
UniRef50_C4G5S2 Putative uncharacterized protein n=1 Tax=Abiotro...   225   8e-58
UniRef50_A8ST52 Putative uncharacterized protein n=2 Tax=Clostri...   225   1e-57
UniRef50_C1P783 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36...   225   1e-57
UniRef50_UPI0001788F0C Cof-like hydrolase n=1 Tax=Geobacillus sp...   225   2e-57
UniRef50_B9EBT4 Putative uncharacterized protein n=1 Tax=Macroco...   224   2e-57
UniRef50_Q04BG8 Predicted hydrolase of the HAD superfamily n=13 ...   224   2e-57
UniRef50_A7VNH3 Putative uncharacterized protein n=1 Tax=Clostri...   224   2e-57
UniRef50_C7HRV4 Hydrolase (HAD superfamily) n=1 Tax=Anaerococcus...   224   2e-57
UniRef50_C0CY86 Putative uncharacterized protein n=3 Tax=Clostri...   224   2e-57
UniRef50_D0Z8V8 Hydrolase, Cof family n=1 Tax=Edwardsiella tarda...   224   2e-57
UniRef50_C6PUS4 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...   224   2e-57
UniRef50_A6LS28 Cof-like hydrolase n=4 Tax=Bacteria RepID=A6LS28...   224   2e-57
UniRef50_Q7MFQ8 Predicted hydrolase n=24 Tax=Vibrionales RepID=Q...   224   2e-57
UniRef50_C4V674 HAD superfamily hydrolase n=2 Tax=Selenomonas Re...   224   3e-57
UniRef50_C4L3T6 Cof-like hydrolase n=2 Tax=Exiguobacterium RepID...   223   4e-57
UniRef50_A7AZV2 Putative uncharacterized protein n=1 Tax=Ruminoc...   223   5e-57
UniRef50_C2KAT0 Possible sugar-phosphatase n=1 Tax=Chryseobacter...   223   5e-57
UniRef50_C7XLV6 Putative uncharacterized protein n=1 Tax=Lactoba...   223   5e-57
UniRef50_Q8ELU0 Hypothetical conserved protein n=1 Tax=Oceanobac...   223   6e-57
UniRef50_D2RIN9 Cof-like hydrolase n=2 Tax=Acidaminococcus RepID...   222   7e-57
UniRef50_UPI0001C430CB Cof-like hydrolase n=1 Tax=Bacillus pseud...   222   7e-57
UniRef50_A5UZ29 Cof-like hydrolase n=2 Tax=Roseiflexus RepID=A5U...   222   8e-57
UniRef50_UPI0001C34D0C Cof-like hydrolase n=2 Tax=Clostridium Re...   222   8e-57
UniRef50_C0CQY6 Putative uncharacterized protein n=2 Tax=Clostri...   222   8e-57
UniRef50_D1PP54 HAD hydrolase, IIB family n=1 Tax=Subdoligranulu...   222   8e-57
UniRef50_B0TIL9 Cof-like hydrolase n=1 Tax=Heliobacterium modest...   222   9e-57
UniRef50_P42962 Uncharacterized protein ycsE n=9 Tax=Bacillus Re...   222   9e-57
UniRef50_C9LLD7 HAD hydrolase, IIB family n=1 Tax=Dialister invi...   222   9e-57
UniRef50_A6TMX9 Cof-like hydrolase n=1 Tax=Alkaliphilus metallir...   222   1e-56
UniRef50_C4FTB9 Putative uncharacterized protein n=1 Tax=Catonel...   222   1e-56
UniRef50_Q042H4 Predicted hydrolase of the HAD superfamily n=11 ...   222   1e-56
UniRef50_P74365 Sll1524 protein n=1 Tax=Synechocystis sp. PCC 68...   222   1e-56
UniRef50_A5ZMH1 Putative uncharacterized protein n=2 Tax=Clostri...   221   2e-56
UniRef50_Q45494 Putative phosphatase ykrA n=4 Tax=Bacillus RepID...   221   2e-56
UniRef50_C6W4G6 Cof-like hydrolase n=1 Tax=Dyadobacter fermentan...   221   2e-56
UniRef50_C8ZWL6 Hydrolase n=9 Tax=Lactobacillales RepID=C8ZWL6_E...   221   2e-56
UniRef50_Q03GE4 Predicted hydrolase of the HAD superfamily n=2 T...   221   2e-56
UniRef50_D0BJQ5 Cof family protein n=2 Tax=Granulicatella RepID=...   221   2e-56
UniRef50_C4FWW1 Putative uncharacterized protein n=1 Tax=Catonel...   220   3e-56
UniRef50_A8VQS9 Type III restriction enzyme, res subunit n=1 Tax...   220   3e-56
UniRef50_Q5WEW5 HAD superfamily hydrolase n=1 Tax=Bacillus claus...   220   3e-56
UniRef50_C3RM99 Hydrolase n=3 Tax=Bacteria RepID=C3RM99_9MOLU         220   4e-56
UniRef50_Q03FP9 Predicted hydrolase of the HAD superfamily n=28 ...   220   4e-56
UniRef50_C8P0W5 Phosphatase YidA n=1 Tax=Erysipelothrix rhusiopa...   220   4e-56
UniRef50_B9RS16 Phosphatase yidA, putative n=1 Tax=Ricinus commu...   220   4e-56
UniRef50_B9Z762 Cof-like hydrolase n=1 Tax=Lutiella nitroferrum ...   220   4e-56
UniRef50_C4L8T6 Cof-like hydrolase n=1 Tax=Tolumonas auensis DSM...   220   4e-56
UniRef50_A7VVP1 Putative uncharacterized protein n=1 Tax=Clostri...   220   4e-56
UniRef50_D1AM09 Cof-like hydrolase n=6 Tax=Bacteria RepID=D1AM09...   220   5e-56

Sequences not found previously or not previously below threshold:

UniRef50_C4LAX9 Cof-like hydrolase n=28 Tax=Bacteria RepID=C4LAX...   256   7e-67
UniRef50_Q0SVE4 HAD hydrolase, IIB family n=17 Tax=Clostridium R...   249   6e-65
UniRef50_A6P2T9 Putative uncharacterized protein n=1 Tax=Bactero...   244   3e-63
UniRef50_C9AY54 HAD-superfamily hydrolase n=4 Tax=Enterococcus R...   240   3e-62
UniRef50_UPI0001C365F0 putative haloacid dehalogenase-like hydro...   239   5e-62
UniRef50_Q5DYX0 Predicted hydrolase n=65 Tax=Bacteria RepID=Q5DY...   237   3e-61
UniRef50_C2LH85 HAD superfamily hydrolase n=3 Tax=Enterobacteria...   236   8e-61
UniRef50_C2D902 HAD family hydrolase n=1 Tax=Atopobium vaginae D...   235   1e-60
UniRef50_B6XF55 Putative uncharacterized protein n=2 Tax=Provide...   234   3e-60
UniRef50_D2LWT0 Cof-like hydrolase n=1 Tax=Bacillus cellulosilyt...   231   2e-59
UniRef50_A1SVY5 Cof-like hydrolase n=4 Tax=Bacteria RepID=A1SVY5...   231   2e-59
UniRef50_P70947 Putative phosphatase yitU n=101 Tax=Firmicutes R...   231   3e-59
UniRef50_Q0STC6 HAD hydrolase, IIB family n=9 Tax=Clostridium pe...   230   4e-59
UniRef50_C7TGI6 Hydrolase of the HAD superfamily n=9 Tax=Lactoba...   230   5e-59
UniRef50_C5D2V8 Cof-like hydrolase n=3 Tax=Geobacillus RepID=C5D...   229   6e-59
UniRef50_C6VMV1 HAD superfamily hydrolase n=10 Tax=Lactobacillal...   229   7e-59
UniRef50_C6IVB2 Predicted protein n=3 Tax=Bacillales RepID=C6IVB...   229   9e-59
UniRef50_C5RAW2 HAD superfamily hydrolase n=1 Tax=Weissella para...   229   9e-59
UniRef50_C8P4G9 Cof family protein n=1 Tax=Lactobacillus antri D...   229   1e-58
UniRef50_A6BG65 Putative uncharacterized protein n=5 Tax=Clostri...   228   1e-58
UniRef50_B9DRH4 Haloacid dehalogenase-like hydrolase n=11 Tax=St...   228   1e-58
UniRef50_C1I4C1 HAD superfamily hydrolase n=1 Tax=Clostridium sp...   227   3e-58
UniRef50_D0BK11 Cof family protein n=2 Tax=Granulicatella RepID=...   227   4e-58
UniRef50_C6VK79 HAD superfamily hydrolase n=17 Tax=Lactobacillus...   226   5e-58
UniRef50_Q1WSZ0 Hydrolase, HAD superfamily n=9 Tax=Lactobacillal...   226   6e-58
UniRef50_C0ZHG1 Putative uncharacterized protein n=1 Tax=Breviba...   226   6e-58
UniRef50_C1QEL1 HAD-superfamily hydrolase, subfamily IIB n=3 Tax...   225   8e-58
UniRef50_A9VQD5 Cof-like hydrolase n=72 Tax=Bacillus RepID=A9VQD...   224   2e-57
UniRef50_C5NUB3 Hydrolase n=3 Tax=Firmicutes RepID=C5NUB3_9BACL       224   3e-57
UniRef50_B4SM39 Cof-like hydrolase n=4 Tax=Bacteria RepID=B4SM39...   223   4e-57
UniRef50_B6WB05 Putative uncharacterized protein n=1 Tax=Anaeroc...   222   7e-57
UniRef50_Q5WGE2 HAD superfamily hydrolase n=2 Tax=Bacillus RepID...   222   9e-57
UniRef50_C6CZV3 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CZ...   222   1e-56
UniRef50_B6FMU0 Putative uncharacterized protein n=1 Tax=Clostri...   222   1e-56
UniRef50_Q042G1 Predicted hydrolase of the HAD superfamily n=8 T...   222   1e-56
UniRef50_C9PP31 Phosphatase YbhA n=1 Tax=Pasteurella dagmatis AT...   221   2e-56
UniRef50_C5RDT1 Cof-like hydrolase n=1 Tax=Clostridium cellulovo...   221   2e-56
UniRef50_B0MA46 Putative uncharacterized protein n=1 Tax=Anaeros...   220   3e-56
UniRef50_B9DIS6 Predicted hydrolases of the HAD superfamily n=61...   220   4e-56
UniRef50_D1CC39 Cof-like hydrolase n=1 Tax=Thermobaculum terrenu...   220   5e-56
UniRef50_C0XNN9 HAD family hydrolase n=3 Tax=Corynebacterium Rep...   219   6e-56
UniRef50_C5RAP3 Haloacid dehalogenase (HAD) superfamily hydrolas...   219   6e-56

>UniRef50_P27848 Uncharacterized protein yigL n=168 Tax=Bacteria RepID=YIGL_ECOLI
          Length = 266

 Score =  390 bits (1004), Expect = e-107,   Method: Composition-based stats.
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS
Sbjct: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE
Sbjct: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT
Sbjct: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD
Sbjct: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240

Query: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266
           LHPELEVIGTNADDAVPHYLRKLYLS
Sbjct: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266


>UniRef50_A0KR21 Hydrolase, Cof family n=3 Tax=Aeromonadaceae RepID=A0KR21_AERHH
          Length = 270

 Score =  318 bits (815), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 123/264 (46%), Positives = 166/264 (62%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+VV SDLDGTLL+  H +SP  ++TL  L  +GI FV ATGRHHVDV  IRD L +  
Sbjct: 1   MYKVVVSDLDGTLLNGQHQISPRTRDTLHRLVDQGIKFVVATGRHHVDVRSIRDTLGLDI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGA VHD    LIF   L   +A++L   +  +P I  N+Y  DEW +    P  
Sbjct: 61  YLITSNGAVVHDKQDQLIFNQALPDGVAAELIA-LERDPSIHINLYYGDEWLVEEEMPWL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++F  E+ F Y L +      + V+KVF+  + HE+LL +E  +N R+GDR+NV+FS   
Sbjct: 120 LQFHHESGFSYRLTDLASHPLDKVNKVFYIGE-HEKLLQIEAELNQRYGDRLNVTFSLPD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM  GV KG+A+ AV ++ G  +   +AFGDGMND EMLSM G+G +MG+AH RLK 
Sbjct: 179 CLEVMHAGVHKGNAVRAVLEQHGLEMSQAVAFGDGMNDFEMLSMVGRGVVMGNAHDRLKL 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                E   ++ +D V  YL +L+
Sbjct: 239 ALANHEQTLSSDEDGVAVYLEQLF 262


>UniRef50_Q7MQB3 Predicted hydrolase n=59 Tax=Gammaproteobacteria RepID=Q7MQB3_VIBVY
          Length = 276

 Score =  299 bits (766), Expect = 8e-80,   Method: Composition-based stats.
 Identities = 129/265 (48%), Positives = 188/265 (70%), Gaps = 2/265 (0%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VASDLDGTLL+P+H LS ++K+TLK L  +G  F+FATGRHHVDV  IR  + I +YM
Sbjct: 12  KIVASDLDGTLLAPNHQLSEFSKQTLKALHEQGYTFIFATGRHHVDVAGIRAQVGIPAYM 71

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ITSNGARVHD    L+++ N+  ++   +  +V  +P+I  ++Y++++W +NR      +
Sbjct: 72  ITSNGARVHDQHDQLMYSKNVPAELVQPVIDIVKQDPEIFVHLYQNEDWRLNREDEVMRK 131

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCD--SHEQLLPLEQAINARWGDRVNVSFSTLT 180
           F +E  F Y +Y+      +G++K+FFT     HE L+  E  +   +GD++N++FST  
Sbjct: 132 FHEETGFTYKVYDIDNAPTDGIAKIFFTHPEQDHEHLVGFENQLREAFGDQLNIAFSTPW 191

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVMA  VSKG AL+AVA+ LG +L++C+AFGDGMND EMLSMAGKG +M ++H+++K 
Sbjct: 192 CLEVMAAEVSKGDALKAVAESLGLTLENCVAFGDGMNDVEMLSMAGKGLVMETSHEKVKK 251

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P+ E+IG+NADDAV HYL+K  L
Sbjct: 252 ALPDNEIIGSNADDAVAHYLQKHLL 276


>UniRef50_C6JR95 Hydrolase n=2 Tax=Fusobacterium RepID=C6JR95_FUSVA
          Length = 266

 Score =  286 bits (732), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 101/265 (38%), Positives = 173/265 (65%), Gaps = 2/265 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ +  DLDGTLL+  HT+S Y ++ +K +T  G+ F  ATGRHH+D  + ++ L + SY
Sbjct: 3   YKAIVCDLDGTLLNSQHTISKYTRDVIKDVTNLGVKFFIATGRHHMDALKFKEMLGLDSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+SNGAR+H+ +  +IF  ++ +++++++F  +N N +I  N+Y+DD WF  +   E  
Sbjct: 63  LISSNGARIHNENNEIIFKGDIPKELSNEIFD-LNINEEIYKNIYKDDFWFSEKPLDEAH 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            + KE+ F Y++ +   L+   V K F+  +  + +  LE  IN ++G+R+N++ S   C
Sbjct: 122 EYHKESGFTYSVRKFSELKNSEVIKFFYINEDEKLIRNLENEINEKFGNRINLTLSLPIC 181

Query: 182 LEVMAGGVSKGHALE-AVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           LE+M  G+SKG+A++  +  K   + ++ I+FGDG+ND EML + G+G +MG+ + RLK+
Sbjct: 182 LEIMNKGISKGNAIKDILLPKFKITPEEVISFGDGLNDYEMLDIVGEGLLMGNCNPRLKE 241

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
           L P  +VIG N +D V  YL+K++L
Sbjct: 242 LLPNNKVIGRNDEDGVAEYLKKVFL 266


>UniRef50_C3WDD5 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WDD5_FUSMR
          Length = 265

 Score =  284 bits (727), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 105/264 (39%), Positives = 159/264 (60%), Gaps = 1/264 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ +  DLDGTLL+  H LS   KE +K +   G     ATGRHH+D   I+  L + SY
Sbjct: 3   YEAIVCDLDGTLLNEKHQLSDETKEVIKKVKDTGKKIFIATGRHHLDALAIKKQLGLDSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+SNGAR+HD   N ++  N+D + A+ +   V  N +I  ++Y D +W++  H+ E +
Sbjct: 63  LISSNGARIHDEHNNEVYERNIDEETANFILN-VKCNKEIERHIYTDTKWYVEEHKEEYI 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            F KE+ F Y + +   +  E   K+FF   + E+L  LE+      GD+V+++ S   C
Sbjct: 122 EFHKESGFLYEVKDFSKIVGEKFIKIFFISKNQEELFKLEKYFEEVIGDKVSITLSGPEC 181

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+M   V+KG A++ + +KL   L++ +AFGDG+ND EMLS  GKG +MG+  QRL++ 
Sbjct: 182 LELMTKNVTKGEAVKNIMEKLNIPLENTMAFGDGLNDYEMLSEVGKGLLMGNCAQRLREK 241

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
            P  E+IG N D+ V  YLRK +L
Sbjct: 242 LPNNEMIGKNIDNGVAKYLRKTFL 265


>UniRef50_A8GAR8 HMP-PP phosphatase n=39 Tax=Enterobacteriaceae RepID=COF_SERP5
          Length = 274

 Score =  280 bits (717), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 109/265 (41%), Positives = 153/265 (57%), Gaps = 3/265 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++ A D+DGTLL+PDH + P     LK L  R +   FATGRH++D   I   L ++ 
Sbjct: 1   MYRLAAFDMDGTLLTPDHRVGPETLAVLKQLVEREMVVTFATGRHYLDAQPIMAQLGLQG 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+IT NG RV+D  G  + A +L  DIA ++    + + D   +V+RD+ W      PEE
Sbjct: 61  YLITGNGTRVYDDRGQQLQATDLPADIAEEVL-HTHWHTDASMHVFRDEGWMTEFAVPEE 119

Query: 121 M-RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
           M R    + F Y L E   L   G SKV F    HE+LL L+  +   +  RV++ FS  
Sbjct: 120 MLRAHHLSGFHYQLTELRRLPAFGNSKVCFAG-PHEELLKLQVQLRRHFAARVDLCFSAY 178

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
            CLEV+  G +KG AL+ +++ LG  + +C+AFGD MND EML+  G G +MG+A  +LK
Sbjct: 179 ECLEVLPLGCNKGSALDMLSRHLGLKMAECMAFGDAMNDKEMLATVGHGVVMGNALPQLK 238

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
            L P+L+VIG     AV HYL+   
Sbjct: 239 SLLPQLQVIGHCEQQAVAHYLQHWL 263


>UniRef50_A6FJC9 Putative uncharacterized protein n=1 Tax=Moritella sp. PE36
           RepID=A6FJC9_9GAMM
          Length = 263

 Score =  278 bits (713), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 119/265 (44%), Positives = 167/265 (63%), Gaps = 2/265 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+V+ SDLDGTLL+P H +S   K T+  L  +G  F+ ATGRHHVDV  IR  ++ + 
Sbjct: 1   MYKVIVSDLDGTLLTPAHIVSEQTKITIHKLLKQGKKFIIATGRHHVDVEAIRKTIDAEI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGARVH+  G LI++ N+  DIA  +   +N    I  N++RDDEWF+N   PE 
Sbjct: 61  YLITSNGARVHNHKGELIYSKNIATDIA-QMITEINLPETIQANIFRDDEWFVNTPNPEV 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           + F +++ F Y + +   L+  G++K FF C  H+ L+ L   INA++  ++NVSFS   
Sbjct: 120 LNFSQDSTFSYQVVDLEALDKAGIAK-FFFCGPHKDLVALAAQINAQYSTQLNVSFSLPE 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM   V+K  AL  V +  G+++ + +AFGDGMND EML    KG +MG+A   LK 
Sbjct: 179 CLEVMDINVNKAQALAEVLRIKGFTMAETVAFGDGMNDVEMLQAVDKGLVMGNASTMLKA 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P+ E+IG +ADD V  Y+ K  L
Sbjct: 239 TLPDFEIIGDSADDGVAQYIEKYIL 263


>UniRef50_C3WN06 Hydrolase n=12 Tax=Fusobacterium RepID=C3WN06_9FUSO
          Length = 267

 Score =  276 bits (707), Expect = 5e-73,   Method: Composition-based stats.
 Identities = 96/263 (36%), Positives = 156/263 (59%), Gaps = 2/263 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+  H +S +    +K +   G+ F+ ATGR ++D    RD+LE+KSY
Sbjct: 3   YKLIVCDMDGTLLTSSHKISDHTANIIKKIEDSGVKFMIATGRPYLDARHYRDSLELKSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +ITSNGAR HD D N I   N+ +++   L        DI  N+Y DD+W +       +
Sbjct: 63  LITSNGARAHDEDNNPIVVENIPKELVKRLLNY-KVGKDIHRNIYLDDDWIIEYEIDGLV 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            F KE+ + + + +    + + V+K+FF  ++ E +  LE+ +   + D ++++ S+  C
Sbjct: 122 EFHKESGYGFNIDDLSKYQNQEVAKIFFLGENKE-IEELEKKMKKDFKDELSITVSSPFC 180

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE M  GV+K   L+ V K L    ++ IAFGD MND EMLS+ GK  IMG+A++RL + 
Sbjct: 181 LEFMKKGVNKAETLKKVLKILDIKPEEVIAFGDSMNDYEMLSLVGKPFIMGNANKRLIEA 240

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
            P +EVIG N +D +   L++++
Sbjct: 241 LPNVEVIGNNNEDGIGEKLQEIF 263


>UniRef50_A1HSX6 Cof-like hydrolase n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HSX6_9FIRM
          Length = 272

 Score =  273 bits (699), Expect = 5e-72,   Method: Composition-based stats.
 Identities = 76/264 (28%), Positives = 118/264 (44%), Gaps = 4/264 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A DLD TLL     +S  A+E +    ARG+    ATGR +         L +   
Sbjct: 3   IKLIAVDLDDTLLDNSLAVSARAREAIAQAVARGVTVTVATGRMYRSALPYARQLGLDVP 62

Query: 62  MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NGA +   L G ++    L  D+A D+  +          VY DD  ++       
Sbjct: 63  LITYNGALIKAALSGEVLLHRPLAEDVARDVLALSRQQ-GWYIQVYLDDVLYVTELNDRA 121

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           + +   A  +       L    G             +L +++ + AR+GDR+    S   
Sbjct: 122 LYYETIAGVKAVPIGDRLYSLPGAPTKLLVMAEPADILRIQEEVQARFGDRLYAVVSKPN 181

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE++   V+KG AL  +A+KLG S  + +A GD  ND +ML  AG G  MG+A QR+K 
Sbjct: 182 YLEMVHPAVNKGAALAFLAEKLGISRDEVMAIGDSYNDLDMLEYAGFGVAMGNASQRVKA 241

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
           +     V   N +D V   + K+ 
Sbjct: 242 VAQA--VTRGNDEDGVAEAIEKIL 263


>UniRef50_A1V919 HAD hydrolase, IIB family n=56 Tax=Betaproteobacteria
           RepID=A1V919_BURMS
          Length = 273

 Score =  272 bits (698), Expect = 6e-72,   Method: Composition-based stats.
 Identities = 102/266 (38%), Positives = 155/266 (58%), Gaps = 3/266 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ +A+DLDGTLL+ DH L PY  +T++ L   G+ FV ATGRH+ DV  IRD L I+ 
Sbjct: 1   MYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDLLGIRP 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLF--GVVNDNPDIITNVYRDDEWFMNRHRP 118
           Y+ITSNGARVH  D   I A ++  D    L    +V  +  +I N++ +D W ++R  P
Sbjct: 61  YLITSNGARVHGPDDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAP 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           + + F +++ F+Y + +    +   ++KV +  +  E L  +   +  R+GD + V++S 
Sbjct: 121 QLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEP-EDLAVVSGNLARRFGDALYVTYSL 179

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
             CLEVM   VSKG AL  V ++LG     C+AFGD MND ++L  AG   +M +A+  L
Sbjct: 180 PDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMNNANPDL 239

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
               P++  IG N +  V  +LR L+
Sbjct: 240 ALRLPKVPRIGNNFEAGVARHLRALF 265


>UniRef50_Q8KA73 Uncharacterized protein BUsg_029 n=5 Tax=Buchnera aphidicola
           RepID=Y029_BUCAP
          Length = 274

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 121/265 (45%), Positives = 183/265 (69%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A+DLDGTLLSP++ ++ Y ++ +K L  +G  FVFA+GRH++D+ +IRD L IK 
Sbjct: 1   MYRIIAADLDGTLLSPENKITKYTEKIIKFLIEKGFYFVFASGRHYIDIMKIRDTLNIKV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +MITSNGA+V+DL+  LIF ++LD +IA  L  +   + DIIT VYR+++W++N ++ + 
Sbjct: 61  FMITSNGAQVYDLNNVLIFENHLDEEIALKLCKMKYLDADIITQVYRNNQWYINNNKIDN 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                 +  +Y  + P +   + VSKVFFT  + ++L  L++ I +  G+RVNV FS   
Sbjct: 121 NFCPTLSSLRYKYFCPDVFNFKKVSKVFFTSHNLKKLHTLQKDIISFLGNRVNVHFSVPG 180

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV++G VSKG+ L+ ++  LG SLK+CI FGDGMND +MLS++GK CIM +A   LK 
Sbjct: 181 CLEVVSGEVSKGYGLKLISNILGISLKECITFGDGMNDQDMLSISGKACIMENADSSLKK 240

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P  EVIG+N +D V  +L K ++
Sbjct: 241 NLPYAEVIGSNKNDGVAVFLNKNFI 265


>UniRef50_P44771 Uncharacterized protein HI0597 n=32 Tax=Pasteurellaceae
           RepID=Y597_HAEIN
          Length = 272

 Score =  267 bits (684), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 115/264 (43%), Positives = 164/264 (62%), Gaps = 1/264 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
           ++ + SDLDGTLL+P+H +     +TL+ L  +G++ + ATGR+H DV  I   +   ++
Sbjct: 5   FRAMVSDLDGTLLTPEHLVGDLTIDTLRALEQKGVDIILATGRNHTDVSSILGKIGAERA 64

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            MITSNGARV DL GNL+++++L  ++  +L+    D   +  N Y+D+ WF N+  P  
Sbjct: 65  VMITSNGARVRDLQGNLLYSNSLPEELVLELYKTPFDTSKVCMNSYQDEGWFTNKDIPAM 124

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            +F KE+ F Y + +       G  KVFF   + E L+ +E  +  ++GD   + +S L 
Sbjct: 125 RQFHKESGFDYNVVDFSKHHGRGTEKVFFIGKTPEDLVEVETYLRDKFGDVTTIVYSALA 184

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM   VSKG AL+ + +   Y LKDCIAFGDGMND EMLS AGKGCIM  A  RLK 
Sbjct: 185 CLEVMNKNVSKGDALKHLLESREYELKDCIAFGDGMNDVEMLSWAGKGCIMKDADIRLKM 244

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
             PELEVIG+N +++V  YLR  +
Sbjct: 245 ACPELEVIGSNKEESVARYLRTQF 268


>UniRef50_Q4D2M6 Haloacid dehalogenase-like hydrolase, putative n=2 Tax=Trypanosoma
           cruzi RepID=Q4D2M6_TRYCR
          Length = 311

 Score =  266 bits (682), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 112/271 (41%), Positives = 159/271 (58%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
           Y  V +DLDGTLL+  H++S Y  ETL+LL  +GI  +FATGR + DV    +   +   
Sbjct: 38  YLAVVTDLDGTLLNEHHSISEYTAETLRLLKNKGIAIIFATGRAYFDVFHTVEKCGLHGG 97

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPD-------IITNVYRDDEWFM 113
           Y+ITSNGARV D     I  H++D ++ S+L  +  D+ +         TN YR +EW  
Sbjct: 98  YLITSNGARVFDPQRRAIVTHDVDPEVVSELINIKLDDENQDAEDSSFATNFYRHEEWLT 157

Query: 114 NRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
           NR     +  +  + F+Y   +      +GV  VFF  + HE LL +E+ + +R+  +V 
Sbjct: 158 NRGSERMLVAYAGSGFRYKEMDLNTCPHDGVHSVFFLGE-HEVLLRVEKVLESRFQGKVE 216

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
            S S    L+ +  GV+KG+A+  VA+ LG S K+ IAFGDGMND +ML MAGKGC+MG+
Sbjct: 217 HSMSHPLVLDTVRWGVNKGNAMCEVAQLLGISAKEIIAFGDGMNDLKMLQMAGKGCVMGN 276

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           A  RLK+  P LEVIG N +D V   LR ++
Sbjct: 277 AQSRLKEALPHLEVIGCNTEDGVARKLRAVF 307


>UniRef50_Q0B097 Putative uncharacterized protein n=1 Tax=Syntrophomonas wolfei
           subsp. wolfei str. Goettingen RepID=Q0B097_SYNWW
          Length = 268

 Score =  265 bits (678), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 68/267 (25%), Positives = 123/267 (46%), Gaps = 6/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLD TLL     +     E +  +  +G+    ATGR           L++   
Sbjct: 3   IELVAIDLDDTLLDSTWKIPESCLEAISQVQRKGVRVTLATGRMFRSALPYAQQLKVDIP 62

Query: 62  MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT  GA V +     +++   L R +A+++     +   I    Y +D + + R  PE 
Sbjct: 63  LITYQGALVKNSFSQEVLYYEPLPRKLAAEIMIFFKER-GIFYQSYFNDCFCIERWSPEA 121

Query: 121 MRFFKEAVFQYALYEPGLL--EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
             + + +  +   Y+  +     +   K+  +      +L +E+ +N R+G+ + ++ S 
Sbjct: 122 QYYAELSGMEPLFYDDLIAVSREQDTPKILASIFDERLMLAIEEELNRRYGEELYITRSK 181

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LEVM   V KG AL+ +A+  G   +  +AFGD  ND  M+  AG G  MG+A + +
Sbjct: 182 PVFLEVMKRSVDKGLALKMLARYFGIPREKVLAFGDSYNDLAMIKWAGIGVAMGNAPEVV 241

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K+      +  +N ++ V H L +L L
Sbjct: 242 KEAAD--YLAPSNEEEGVAHVLHELIL 266


>UniRef50_Q2RLU7 HAD-superfamily hydrolase subfamily IIB n=1 Tax=Moorella
           thermoacetica ATCC 39073 RepID=Q2RLU7_MOOTA
          Length = 272

 Score =  263 bits (673), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 78/269 (28%), Positives = 123/269 (45%), Gaps = 9/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLDGTLL+ D  + P A+E ++ +  +GI    ATGR           L ++  
Sbjct: 4   IRLVALDLDGTLLTDDIVIEPRAREAIRKVKEKGITVTLATGRMFSSARPYAVELGLELP 63

Query: 62  MITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I  +GA+V H   G ++F   L   +A  L   + +      NVY DD  ++   + E 
Sbjct: 64  LIVYHGAQVRHSTTGEILFERTLPVPLALRLIKNIKEF-GYPYNVYLDDRLYVESIQAEN 122

Query: 121 MRFFKEAVFQYALYEPGLL----EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             +   A       E  L     +P+G  K+    D    L PLE AI    G  + ++ 
Sbjct: 123 EEYAWRAGVDLHRVEDMLTFLEQQPKGPLKIVALHDGP-ALDPLEAAIRREAGAGIYITR 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S  T LE++   V+K   L+A+A+  G S ++ +  GD  ND +M   AG    M +A +
Sbjct: 182 SMPTYLELLNPEVNKARGLQALAELEGISPEEIMVCGDSYNDVQMFRYAGLAVAMANAPE 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +++       V G+N D  V   L K  L
Sbjct: 242 KVRAEAD--YVTGSNNDGGVAQALEKFVL 268


>UniRef50_C6CW76 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CW76_PAESJ
          Length = 268

 Score =  263 bits (673), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 74/266 (27%), Positives = 131/266 (49%), Gaps = 4/266 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+D TLL+ D  ++   K+ ++   A G+    ATGR +    +I D +++  
Sbjct: 1   MYKLIAIDVDDTLLNDDLIVTEGTKKAMEDAIALGVTVTLATGRMYASAKKIADQIQLNV 60

Query: 61  YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +IT  G+ V  L DG +++   + +D A +L+  + +   +   +Y DD  ++     +
Sbjct: 61  PIITYQGSLVKTLLDGEVLYERCVPQDAAKELYA-ITEQRGLHLQLYADDILYVKEANEK 119

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            +++       Y + E      +  +      D    L  L + +    GDRV+++ S  
Sbjct: 120 AIKYSTLTNIPYVVAEDFEALLDKPNNKMLIIDDPAYLDQLAEELKPIIGDRVHITKSKP 179

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             LE M    +KGHAL  +A+ LG  ++  IA GD  ND EM+  AG G  MG+A  +LK
Sbjct: 180 HYLEFMHKEGTKGHALRFMAEHLGCGVEQTIAIGDAWNDHEMIEAAGLGVAMGNATPKLK 239

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
           ++     +  TN ++ V H + K  L
Sbjct: 240 EIAD--YITLTNNEEGVRHVIEKFVL 263


>UniRef50_C9KQV0 HAD-superfamily hydrolase, subfamily IIB n=2 Tax=Veillonellaceae
           RepID=C9KQV0_9FIRM
          Length = 309

 Score =  261 bits (667), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 62/265 (23%), Positives = 105/265 (39%), Gaps = 5/265 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++  +DLDGTLL     +     E ++     G+    ATGR +     + + L +   +
Sbjct: 42  KLFVTDLDGTLLPSGKDVPRENIEAVQQAVRAGVIVTIATGRMYRAALPVAEALGVDVPI 101

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           IT NGA +    G +     L  ++   +     +        Y  DE ++  H      
Sbjct: 102 ITYNGALIKSTQGKVYHTSYLKPEVIRQVVDFCQEQ-GWYLQSYSRDELWVPVHDEHAQH 160

Query: 123 FFKEAVFQYALYEPGLLEPE--GVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           + +E      +     L  +   V K+    +  E+       +N R+G  +    S   
Sbjct: 161 YEQEQKVTGHVVGWDGLCEQTQEVCKLLTVSEDGEETNRRLAILNERFGKEIVAMQSNAR 220

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
             E++  GVSK   +  +A KLG +++D +A GD  ND  ML  AG    MG+A   +K 
Sbjct: 221 YGEIVNPGVSKAEGIRRLADKLGIAIEDTMAIGDSYNDLPMLKAAGHSVAMGNAVPEVKA 280

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
           +       G   D      +R+L L
Sbjct: 281 VCDYE--TGRCEDFGFAQAIRELVL 303


>UniRef50_C6AQ91 Cof protein n=4 Tax=Bacteria RepID=C6AQ91_AGGAN
          Length = 390

 Score =  259 bits (662), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 67/263 (25%), Positives = 121/263 (46%), Gaps = 6/263 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V SD+DGTLL+  H ++P  +E +K +  RGI F+  + R    +    + L  +  
Sbjct: 132 YKAVFSDIDGTLLNSQHQITPKTEEAIKNILKRGIPFIPVSARPPYAITPYTEQLGSQHG 191

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           MI  +GA + D +   +++  L+      L  ++ D   +  + Y   +WF N    + +
Sbjct: 192 MICYSGALILDKNLTALYSVILEPQDLQKLNELLADFAHLSISYYAGLDWFCNDVNNDWI 251

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           +  +E+       E        V K+     S E++  +E  +       +++  S    
Sbjct: 252 K--QESEITGLSAELLQGNLTEVHKILVMG-SAEEIQTVEPVLKQALP-HLSIHRSKDEY 307

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+     +K  A++ + + LG S +  IAFGD  ND +ML  AG    MG+A   +K +
Sbjct: 308 LEITNPAATKAKAIQFMERHLGISAEQVIAFGDNFNDLDMLQYAGLSVAMGNAPDAIKQV 367

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
               EV  TN +D +   L +++
Sbjct: 368 AK--EVTATNNEDGIALVLNRVF 388


>UniRef50_A6T5I9 HMP-PP phosphatase n=18 Tax=Bacteria RepID=COF_KLEP7
          Length = 272

 Score =  258 bits (660), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 95/260 (36%), Positives = 145/260 (55%), Gaps = 2/260 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++ A D+DGTLL PDH L       LK L  R I   FATGRH +++  +     + +
Sbjct: 1   MAKLAAFDMDGTLLMPDHRLGEKTLSALKRLRERDITLTFATGRHVLEMHHVIGEFSLDA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +++T NG R+H L+G  ++  +L  + A  +      +     +V+ D  WF  + RPE 
Sbjct: 61  FLVTGNGTRIHSLEGEELYRQDLAPEAAEAVL-HGKWDTQASMHVFNDGGWFTGQARPEL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++    + F Y L +   +  + V+K+ F C  H+ L  L   +N   GDR  + FS + 
Sbjct: 120 LQAHVFSGFHYQLCDLKRMSAQHVTKICF-CGDHDDLRRLRIQLNETLGDRAFLCFSAMD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV+  G +KG AL  +++ LG++L++C+AFGD MND EML   G+G IMG+A  +LK 
Sbjct: 179 CLEVLPVGCNKGAALAVLSQHLGFTLQECMAFGDAMNDREMLGSVGRGFIMGNAMPQLKA 238

Query: 241 LHPELEVIGTNADDAVPHYL 260
             P L VIG   + AV H+L
Sbjct: 239 ELPHLPVIGDCRNQAVSHFL 258


>UniRef50_D0A841 Haloacid dehalogenase-like hydrolase, putative n=2 Tax=Trypanosoma
           brucei RepID=D0A841_TRYBG
          Length = 287

 Score =  257 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 110/273 (40%), Positives = 158/273 (57%), Gaps = 11/273 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
           Y+    DLDGTLL+ +H +S Y  +T++ L  R I  V ATGR H DV     +  ++  
Sbjct: 12  YRAAVVDLDGTLLNENHRISAYTLDTIQKLLKRNIPVVIATGRPHPDVFHTIKSCGLQGT 71

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDI--------ITNVYRDDEWF 112
           Y+ITSNGARV D   N+I + NL  D+ S+L G+ +   DI          N+++ DEW 
Sbjct: 72  YVITSNGARVSDPQLNVIASFNLSEDVVSELIGLGSSGEDIQDPKEVPYTVNLFQHDEWV 131

Query: 113 MNRHRPEEMRFFKEAVFQYALYEP-GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
            +  R E ++ F  + F Y + +     + +GV ++ F       L  LE  +  R+  R
Sbjct: 132 TDAAREELLQMFASSGFHYRVVDDLQAHQKDGVHELVFLA-QPNTLHLLEGVVKKRFEGR 190

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           ++V  ST   L+V+    +K  A+  VA+ LG  LKD ++FGDGMND +ML+ AGKG IM
Sbjct: 191 ISVMRSTSITLDVVHHNANKATAMAKVAELLGLELKDIVSFGDGMNDVQMLAAAGKGYIM 250

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G+A QRLKD  P LEVIGTNA+D+V   LR+L+
Sbjct: 251 GNAQQRLKDALPHLEVIGTNAEDSVAKKLRELF 283


>UniRef50_C2KV90 HAD superfamily hydrolase n=1 Tax=Oribacterium sinus F0268
           RepID=C2KV90_9FIRM
          Length = 270

 Score =  257 bits (657), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 76/273 (27%), Positives = 136/273 (49%), Gaps = 12/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           M++ +A DLDGTL + +  +S   K  L+    RG++ + A+GR    + ++ + LE++ 
Sbjct: 1   MFKAIALDLDGTLTNSEKKVSERNKRALQEAIKRGVSIILASGRPTYGMSEVWEALELEK 60

Query: 60  --SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+++ NG+   D     ++F   + R   + +   V +  D+    Y+  E    R 
Sbjct: 61  LGGYVLSYNGSLCMDCKSKEVLFEKTIPRKYYAPIAQAVRE-ADLGLLSYQGKEIVTERP 119

Query: 117 RPEEMRF---FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
               M       +  F+     P  L  E V K+    + HE+LLPL++ +   +G+ ++
Sbjct: 120 EFPYMDRESTINKMPFRKVEDFPNALSEE-VCKLLALGE-HEELLPLKERLEKEYGEELS 177

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           + FS    LE+   GV KG +L+ + +K G+  ++ +AFGDG ND  ML  AGKG  M +
Sbjct: 178 IFFSEPFFLEICPVGVDKGESLKRLLEKKGWKREELMAFGDGGNDLTMLQYAGKGIAMAN 237

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           + + + ++    EV  +N +D V   + K  LS
Sbjct: 238 SQKHVLEIAD--EVTLSNDEDGVAVMVEKYILS 268


>UniRef50_C4LAX9 Cof-like hydrolase n=28 Tax=Bacteria RepID=C4LAX9_TOLAT
          Length = 270

 Score =  256 bits (655), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 65/271 (23%), Positives = 116/271 (42%), Gaps = 8/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY+++A D+DGTLL  D T+S   K  ++    +G+  V A+GR    + +    L +  
Sbjct: 3   MYKLIALDMDGTLLRGDGTISERTKSAIQQARQKGVKVVLASGRPIEGLERYLTELGLTT 62

Query: 59  -KSYMITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y ++ NGA + ++     I +  +      D++  V+    + T+ +  +   ++  
Sbjct: 63  DDDYALSYNGALIKNVGTRENICSQLISGKDLHDVYA-VSQQIGVNTHAFSTELGLISPK 121

Query: 117 RPEEMRFFKE-AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                   ++       L +   L  +         D  E L P  + +   + DR  V 
Sbjct: 122 LSHYTVHERDINGIPLTLIDFNELAEDHQIIKVMLVDEPEILSPGVEQLPVDYYDRFTVV 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE++    +KG+ +  +A  LG   ++ I  GD  NDA ML  AG    MG+A 
Sbjct: 182 RSAPFFLEILNKNSNKGNGVSMLADYLGIKAEEVICVGDAGNDAHMLEYAGLSVAMGNAF 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K +     V  +N +D V H + K  L+
Sbjct: 242 DDIKAIAD--YVTHSNEEDGVAHVIEKFILA 270


>UniRef50_Q3AFE4 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Carboxydothermus
           hydrogenoformans Z-2901 RepID=Q3AFE4_CARHZ
          Length = 266

 Score =  256 bits (655), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 72/267 (26%), Positives = 125/267 (46%), Gaps = 8/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLD T L+ +  +SP  ++ +     +GI    ATGR +    +   +      
Sbjct: 3   YRLLAVDLDDTFLNKELQVSPRVQQAVIEALKKGIIVTLATGRMYRSAKKYAFSFLGDIP 62

Query: 62  MITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NGA + +      ++   +  ++A  ++  V        NVY+DDE  +       
Sbjct: 63  LITYNGALIKYSRSEREVYHQPVPGELALTIYRRVK--GHFHLNVYQDDELLVEEDNQYI 120

Query: 121 MRFFKEAVFQYALYE--PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
             + K A   + +      LL  +  +K+    D  E L  L +  N  +   ++++ S 
Sbjct: 121 RDYSKIAGVPFRVVSNIEELLGKKAPTKLLAIGDPEE-LDQLWEETNGEFRGVLHITKSK 179

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LE +A GV+KG AL+ +A+ LG SL + +A GD  ND EML  AG G  MG+A   +
Sbjct: 180 PHYLEFLAAGVNKGEALKILAQHLGISLTETVAVGDSYNDLEMLEAAGLGVAMGNALPEV 239

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K       V+  N +D + + + ++ L
Sbjct: 240 KRRADL--VVPANDEDGIAYLINEIIL 264


>UniRef50_C3WDI3 Hydrolase n=2 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WDI3_FUSMR
          Length = 267

 Score =  256 bits (654), Expect = 8e-67,   Method: Composition-based stats.
 Identities = 84/264 (31%), Positives = 145/264 (54%), Gaps = 2/264 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V SDLDGTLL+  H +S Y   T++ L  +GI FV ATGRH+ D     + + +  Y
Sbjct: 3   YKIVVSDLDGTLLNSQHRISDYTVSTIRKLEKKGIKFVIATGRHYEDAKYFFNQIGVAKY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+ NG+ +H  + N I   ++DR +   L   +        ++Y+  +W+ +R   + +
Sbjct: 63  LISGNGSFIHSENWNEIGRESIDRKLIKTLLE-LEVEEGTSRSIYKGKDWYTDRIVQDYI 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR-VNVSFSTLT 180
            F KE+ +   +      +     K+FF   + + +  LE+ +     D+ +N++ S  T
Sbjct: 122 DFHKESKYSPQISNLDKFKNVEAEKIFFINPNRKVIEKLEKKMKNLELDKYLNIATSQPT 181

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLE+M+   +KG AL+ + K      K+ I+FG  +ND EML  +G G IMG+  +RLK+
Sbjct: 182 CLEIMSKKANKGEALKTLLKYENIDFKEIISFGAALNDKEMLENSGMGIIMGNGDKRLKE 241

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
           +  E +VIG++ +DA   +L  L+
Sbjct: 242 ILKECKVIGSSDEDAAAKFLENLF 265


>UniRef50_B8I4P5 Cof-like hydrolase n=2 Tax=Clostridium RepID=B8I4P5_CLOCE
          Length = 273

 Score =  255 bits (653), Expect = 9e-67,   Method: Composition-based stats.
 Identities = 73/277 (26%), Positives = 123/277 (44%), Gaps = 17/277 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++VA DLDGTLL  +  +S   K  + +   +G+  V  +GR +         L I  
Sbjct: 1   MYRLVAIDLDGTLLDKNKEISERNKIAIHMAKEKGVKIVICSGRVYSGARIYAKQLGIMD 60

Query: 61  YMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +I  NGA +  + DG +I+++ +  D    +  + ++N  I  +VY  +     R    
Sbjct: 61  PIIACNGAIIRENADGKVIYSNYMHTDDCLKILDIFHENS-IYFHVYAGETMLTERLDYN 119

Query: 120 EMRFFKE----------AVFQYALYEPGLLEPEG-VSKVFFTCDSHEQLLPLEQAINARW 168
            +++++            +      E  L E +G V K+    D  E L  + + ++   
Sbjct: 120 SLKYYERNKALHAKDRVEIDIVTDMEKRLKELDGKVLKLVAVSDDSELLATVRKKLSIV- 178

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
            + V+V+ S     EV+  GV+KG ALE ++  L    ++ IA GD  ND  M   AG G
Sbjct: 179 -ETVDVTSSNYNNFEVVNKGVNKGKALERLSNMLKIPYREIIAIGDNENDIPMFDFAGLG 237

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             MG+     K+      +  TN +D V   + K  L
Sbjct: 238 VAMGNGEDCAKEAAD--YITATNTEDGVAKAIEKFIL 272


>UniRef50_D1AJW8 Cof-like hydrolase n=1 Tax=Sebaldella termitidis ATCC 33386
           RepID=D1AJW8_SEBTE
          Length = 262

 Score =  254 bits (650), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 73/264 (27%), Positives = 133/264 (50%), Gaps = 4/264 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + V SDLDGTLL+ + T+S   KE ++ L   GI F  ATGR  + + +  D+LE+ +
Sbjct: 1   MIKAVFSDLDGTLLNENGTVSEETKEMIEKLKKAGIKFFIATGRSFLAMKRFYDHLELDT 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            ++  NGA +H+ DG  IF   LD  +A +L      N ++  + + +++W++  +    
Sbjct: 61  EIVNYNGAVIHNSDGGKIFELTLDDSVARELIDYGRKN-NLYYHGFSNEKWYLEDYNDTA 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             +  ++  Q  +     +     +K+ F  D+ E    ++  +  ++ +++    S+ T
Sbjct: 120 KAYGAKSQLQENIINFDNMPKLDFNKMMFINDA-ETTKIVDSYVIEKYKNKIYKGLSSPT 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE+M   VSKG+A++ + +K G+   + IAFGD  ND EML     G  M +A+  +K 
Sbjct: 179 FLEIMNPDVSKGNAVKFLLEKYGFQPDEVIAFGDAENDLEMLFSVKYGVAMENANDEVKS 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                 +   N ++ V  +L    
Sbjct: 239 --KVNYIAPKNTENGVALFLEDFL 260


>UniRef50_P54947 Uncharacterized protein yxeH n=10 Tax=Firmicutes RepID=YXEH_BACSU
          Length = 270

 Score =  254 bits (650), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 66/273 (24%), Positives = 117/273 (42%), Gaps = 11/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           MY+++A D+DGTLL+  H ++   ++ L    A G+  V  TGR    V +  D L +  
Sbjct: 1   MYKLIAIDMDGTLLNDHHEVTEEVRDALHAAKAEGVKIVLCTGRPIGGVQRYLDELNLIE 60

Query: 60  --SYMITSNGARVHDLDGNLIFAH-NLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I  NGA V +   N + +  +L  D  + L+ +  +      + +     +    
Sbjct: 61  EGDYVIAYNGALVQNTHTNEVVSELSLGYDDLTSLYDLSLELK-TPMHFFDSSNLYTPNR 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
              E   ++  V Q  L+   + E      + KV F  D  E L  +  +I     ++  
Sbjct: 120 DISEFTVYESYVTQVPLHFRKIDEVPKDILIPKVMFI-DKPENLSRVITSIPKDVREKYT 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +  S     E++    SKG+A+  +A+ LG    + +  GD  ND  M+  AG G  M +
Sbjct: 179 MVRSAPFFYEILHSEASKGNAVRQLAQLLGIEQAEVMCIGDNGNDLTMIEWAGCGVAMAN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A   + +         +N +  V H + +L L+
Sbjct: 239 AIPEVLEAAN--FQTRSNNEHGVAHAIHELVLA 269


>UniRef50_B8DEX6 Phosphatase YidA n=17 Tax=Listeria RepID=B8DEX6_LISMH
          Length = 270

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 75/272 (27%), Positives = 131/272 (48%), Gaps = 11/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           MY+++A D+DGTLL+ DH ++   KE ++    +G+  V  TGR  V V      LE++ 
Sbjct: 1   MYKLIAIDIDGTLLTDDHKVTDEVKEAIRQAKLKGVKVVLCTGRPLVGVENYLTELELRE 60

Query: 60  --SYMITSNGARVHDLDGNLIFAH-NLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NR 115
              Y+I+ NGA V D     + +H  L  D   +++ V  D+ ++  + + D   +  NR
Sbjct: 61  EGDYVISFNGAFVQDTFTKEVISHLTLGIDDLKEIYQVSLDS-NLHMHFFDDKALYTPNR 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGV--SKVFFTCDSHEQLLPLEQAINARWGDRVN 173
              +             +Y+     PE    SK  F  ++ E  + + + I   + ++ +
Sbjct: 120 EIGKYTIVEAYLTGSQLIYKEIENVPEDFIMSKAMFIEEAPELEVGIAK-IPESFREKYH 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +  ST   LE++    SKG+A++ +++K+G    + +  GD  ND  ML  AG G  MG+
Sbjct: 179 LVRSTPFYLEILNRDASKGNAVKELSEKIGIKQSEVMCIGDQENDVTMLEFAGLGIAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A +R+K L        +N D  V   ++K  L
Sbjct: 239 APERIKQLAD--YTTASNNDSGVAKAIQKFVL 268


>UniRef50_A4XJ23 Cof-like hydrolase n=2 Tax=Clostridia RepID=A4XJ23_CALS8
          Length = 296

 Score =  253 bits (648), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 73/267 (27%), Positives = 135/267 (50%), Gaps = 8/267 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++VA+DLD +LLS D  ++P   + ++ L    +  + A+GR +  V +I  +LE   
Sbjct: 31  MIKLVATDLDDSLLSKDLKITPKNLKAIEFLKKNNVILILASGRPYPSVKKIAYDLENFY 90

Query: 61  YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            MIT  GA V+D  D   ++   +  + A +L  +  +  +I  ++Y D+ W++     E
Sbjct: 91  PMITYQGALVYDPKDDRKLYGCEIQPNDAKELIRLAKE-ENIHVHIYIDNVWYVEVFN-E 148

Query: 120 EMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
           ++ ++K       +     LE     V+KV F  D HE+L  L++++   +  + N+ FS
Sbjct: 149 KVEYYKNLTGLEPVKVDNFLEFVDRPVTKVLFF-DEHERLRKLKESLPLEFSKKFNIMFS 207

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LE     VSKG+AL+ +A+       + +A GDG ND  M+  AG G  + +A ++
Sbjct: 208 KPFFLEFTDINVSKGNALKFLAQYYNLKRDEIMAIGDGDNDISMIEYAGIGVAVENATEK 267

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLY 264
           LK++     +  +  +    H + K++
Sbjct: 268 LKEVAS--FITLSCDNSGFAHAVEKVF 292


>UniRef50_Q4Q8C9 Haloacid dehalogenase-like hydrolase, putative n=5
           Tax=Trypanosomatidae RepID=Q4Q8C9_LEIMA
          Length = 284

 Score =  252 bits (646), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 97/279 (34%), Positives = 146/279 (52%), Gaps = 15/279 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
            + V +DLDGTLL P H +S YA E LK +  +GI F+ ATGR + +V     +  +   
Sbjct: 6   IKAVVTDLDGTLLDPQHCISNYAAEVLKKIKEKGICFIVATGRPYAEVFNRIRHCHLAPD 65

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGV---------VNDNPDIITNVYRDDEW 111
           Y+ITSNGAR+HD   N++  HNL  ++   L  V                 TN+YR  EW
Sbjct: 66  YIITSNGARIHDGAFNVVREHNLRPELVESLARVRTVKDPATGAELPKKFTTNIYRGAEW 125

Query: 112 FMNRHRPEEMRFFKE----AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
             ++  PE  + F         +   YE    E   V +++F  D H++L+ L+ A+  +
Sbjct: 126 LTDKSIPEVSKAFHTDFQCTDLRERFYELQASELGDVHEIWFAGD-HDELVLLDNALREK 184

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
           +   +  +FS    L+ +  GV+KG+ +   A+ LG +L +   FGDGMND  ML +   
Sbjct: 185 YPGDLCCTFSLPHLLDCVPAGVNKGNGVREAAEMLGLALDEVACFGDGMNDESMLQVTST 244

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             IM +A QRLKD  P  ++IG+NADD V   L +++ S
Sbjct: 245 SFIMANAQQRLKDAVPHAQIIGSNADDGVAKKLEEMFFS 283


>UniRef50_Q897B3 Putative haloacid dehalogenase-like hydrolase n=1 Tax=Clostridium
           tetani RepID=Q897B3_CLOTE
          Length = 263

 Score =  252 bits (645), Expect = 9e-66,   Method: Composition-based stats.
 Identities = 69/269 (25%), Positives = 138/269 (51%), Gaps = 12/269 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGTLL+ +H +S    +T+K    +GI  +  +GR +         LE K 
Sbjct: 1   MYKLIALDIDGTLLNREHEISDETIDTIKESMDKGIKIILVSGRDYSAAEPYIKKLETKD 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             +  NGA ++D +G +I +  LD++I   +  +  +  DI   ++ ++  ++N    E 
Sbjct: 61  LFLGLNGANIYDNEGKIIHSEYLDKEIVEYIIELC-EKEDIYIVLFIENNTYVN----EI 115

Query: 121 MRFFKEAVFQYALYEPG----LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             F     + +   E G      + + V+K+  T    E+L+P+++ +++++G ++N  F
Sbjct: 116 SDFMGIDNYVFNSIEVGQISKFYKEQNVTKILLT-HKEEKLIPIKEKLDSKYGSKINSQF 174

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE+  G ++KG AL+ + +K     ++ +A GD  ND  M+  AG G  MG+  +
Sbjct: 175 SLPQFLEIFNGKINKGVALKRICEKYKIPKENVMAIGDWDNDITMIKYAGLGIAMGNGSE 234

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +K+      +  +N ++   + ++K  L
Sbjct: 235 NIKEAAD--FITNSNEENGAAYAIKKFVL 261


>UniRef50_A5FGB8 Cof-like hydrolase n=1 Tax=Flavobacterium johnsoniae UW101
           RepID=A5FGB8_FLAJ1
          Length = 281

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 105/259 (40%), Positives = 154/259 (59%), Gaps = 1/259 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +VV SDLDGTLL+P H +S Y K   + L  +    V ATGRHH+D   I + LE+  Y
Sbjct: 12  IKVVVSDLDGTLLNPQHKISDYTKSIFQELHNQNYLIVVATGRHHLDAMAIIETLEVPVY 71

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +++SNGAR+H  +   +FA NLD D+       V  +P I   +++++ W  N+      
Sbjct: 72  LVSSNGARIHSPNKEELFAFNLDSDVVKAALN-VEIDPAITVVLFKENVWQTNKWNERLN 130

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            F  E  ++  L +   LE  G  K+FF+CD HE+L+ L+  + A   + ++ +FS  TC
Sbjct: 131 SFQAELKYRPELVDYKKLEDFGAIKIFFSCDDHEKLVKLKDDVLANSSEHLHHAFSLPTC 190

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE M   + K  A+E V +K GY+L+  ++FGDG ND +MLS +GKG IMG+A   LK+ 
Sbjct: 191 LEFMDKSIDKAVAIEQVLEKEGYTLEQAVSFGDGFNDVQMLSASGKGLIMGNAPAVLKET 250

Query: 242 HPELEVIGTNADDAVPHYL 260
            P+LEVI TNA+D V  Y+
Sbjct: 251 LPDLEVIKTNAEDGVAKYI 269


>UniRef50_A8U9P8 Hydrolase, haloacid dehalogenase-like family protein n=1
           Tax=Carnobacterium sp. AT7 RepID=A8U9P8_9LACT
          Length = 269

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 74/274 (27%), Positives = 120/274 (43%), Gaps = 13/274 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           M ++VA DLDGTLL+ +H +S   KE +K    +G+  V  TGR  + +    + L ++ 
Sbjct: 1   MIKLVAIDLDGTLLNREHIISDENKEVIKKAKEQGVKVVLCTGRPLLGMISYLEELNLRE 60

Query: 60  --SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NG  V   D G ++    L +    ++F +  +       +  D E      
Sbjct: 61  VGDYGITYNGGLVQRTDTGEVLSKKTLTKVEIEEIFALSKEINVPCNFI--DLEKIYEPP 118

Query: 117 RPEEMRFFKEAVFQYALYEPGLLE----PEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
            PE        V +   Y P  +E       ++K  F C     L    + I   + ++ 
Sbjct: 119 YPEGRDSLYPTVMRALPYVPIEMEHVSEDIAINKTVF-CYEQTSLDEAIKKIPVHFHEKY 177

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            +  S    LE+M  GV KG  +  +A  LG+   + ++ GD  NDA M+  AG G  MG
Sbjct: 178 TIMKSRPVLLELMPKGVDKGSGIAVLADLLGFEASEVMSLGDEANDAAMIEYAGMGVAMG 237

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +A   +K +     +  TN +  V H ++K  L+
Sbjct: 238 NATDEIKAMAQ--YITKTNEEHGVAHAIQKFVLN 269


>UniRef50_D1AMP5 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepID=D1AMP5_SEBTE
          Length = 265

 Score =  251 bits (643), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 95/267 (35%), Positives = 147/267 (55%), Gaps = 4/267 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V +DLDGTLL+ +  +S ++KE +  +  +G+ F  ATGR + D  +I + + IK 
Sbjct: 1   MYRAVVTDLDGTLLNNEKEVSEFSKEVINKIREKGVKFFIATGRSYPDTKRIMETIGIKV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLF--GVVNDNPDIITNVYRDDEWFMNRHRP 118
            +ITSNGAR++D +G  I+A++L++     +          +I  N+Y D+ W++     
Sbjct: 61  PLITSNGARINDENGETIYANDLEKKYIRKILEMDYKKYGEEIFLNLYSDNVWYITEEMT 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
            +  F     F          +   VSK FF  D HE L+ LE+ +       VN++  T
Sbjct: 121 MD-PFKDLKYFLPHKITVEEAKQMSVSKFFFIGD-HEHLMRLEKELFLLTDGNVNIAMVT 178

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
             CLEV    V KG+A++ + KK    + + +AFGDG ND EML M GKG +MG+A  +L
Sbjct: 179 PECLEVFDIEVHKGNAIKILMKKEKIKMSEVVAFGDGFNDYEMLKMVGKGYVMGNALYQL 238

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K+  P+ E+IGT   DA    L +L+L
Sbjct: 239 KEALPDNEIIGTCDSDAEAKKLIELFL 265


>UniRef50_B0K874 Cof-like hydrolase n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K874_THEP3
          Length = 274

 Score =  251 bits (641), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 70/275 (25%), Positives = 121/275 (44%), Gaps = 16/275 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+D TLL  D T+S    E L     +G+  V +TGR         D +  ++Y
Sbjct: 3   YKLIAIDMDDTLLRHDKTISKENIEALHKAREKGVYVVISTGRVFASAYAYADMIGFRTY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I SNGA + D D N I+   L+ D   ++  V     +    +  D   F      +  
Sbjct: 63  IIASNGALIRDPDNNTIYESLLNYDSMEEIIKVCQKY-NTYFQLISDKTVFSPEITNKFQ 121

Query: 122 RFFK-------EAVFQYALYEPGLLEPEG----VSKVFFTCDSHEQLLPLEQAINARWGD 170
           R+ +       E        +  L E +     + K+    D  E L  + + ++     
Sbjct: 122 RYAEWNELFKTELKVDVQEVKEPLKELDKLKSSILKIIVFNDDVEVLKSIREELSK--NT 179

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + ++ S +  +E++  GVSKG AL+ +   LG   ++ IA GD  ND EM+  AG G  
Sbjct: 180 SIQITSSYMDNIEIVNKGVSKGRALKILGGYLGIEREEMIAIGDSENDIEMIKFAGLGVA 239

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           + +A   +K +     +  +N +D V + + K  L
Sbjct: 240 VENAIDEVKKVAD--FITKSNMEDGVKYVIDKFIL 272


>UniRef50_B0K375 Cof-like hydrolase n=11 Tax=Thermoanaerobacterales
           RepID=B0K375_THEPX
          Length = 273

 Score =  250 bits (640), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 71/270 (26%), Positives = 123/270 (45%), Gaps = 7/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++  +D DG+LL+ +  +S   KE +K + +RG+ F  ATGR    +      L I +
Sbjct: 1   MYKLFVTDADGSLLNSNSEISDKNKEAIKEVISRGVIFTIATGRMFSSILPYALELNINA 60

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP- 118
            +I+ NGA + D     + + + +  + A     ++ +      N+Y DDE ++      
Sbjct: 61  PVISYNGALIKDIYTKKVYYYNPIQTEDAIFAIRLLKEI-GYHINLYIDDELYVEEITDR 119

Query: 119 --EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
               + F    V      E  L    GV+   +  +  +  + ++  I      R+ +S 
Sbjct: 120 VEWYLSFNNVTVNAVGNLEEFLKRTGGVTAKIYAINDMKNPISIDAEIYDEISKRLTIST 179

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE+ A GVSKG+AL+ +A       +  +A GD +ND  M+  AG G  MG+A  
Sbjct: 180 SGGGHLEINAKGVSKGNALKTLANMYSIKREQVVAIGDNLNDLSMIEYAGLGVAMGNAPD 239

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +K          +N +D V H + K +L+
Sbjct: 240 IVKIKAD--YTTLSNDEDGVAHAIDKFFLN 267


>UniRef50_A7ZIK4 HMP-PP phosphatase n=87 Tax=Bacteria RepID=COF_ECO24
          Length = 272

 Score =  250 bits (639), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 101/260 (38%), Positives = 145/260 (55%), Gaps = 2/260 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++ A D+DGTLL PDH L      TL  L  R I   FATGRH +++  I   L + +
Sbjct: 1   MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+IT NG RVH L+G L+   +L  D+A +L      +     +++ DD WF  +  P  
Sbjct: 61  YLITGNGTRVHSLEGELLHRDDLPADVA-ELVLYQQWDTRASMHIFNDDGWFTGKEIPAL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++ F  + F+Y + +   +    V+K+ F C  H+ L  L+  +    G+R ++ FS   
Sbjct: 120 LQAFVYSGFRYQIIDVKKMPLGSVTKICF-CGDHDDLTRLQIQLYEALGERAHLCFSATD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV+  G +KG AL  + + LG SL+DC+AFGD MND EML   G G IMG+A  +L+ 
Sbjct: 179 CLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRA 238

Query: 241 LHPELEVIGTNADDAVPHYL 260
             P L VIG   + AV HYL
Sbjct: 239 ELPHLPVIGHCRNQAVSHYL 258


>UniRef50_C6P8T7 Cof-like hydrolase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6P8T7_CLOTS
          Length = 293

 Score =  249 bits (637), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 76/277 (27%), Positives = 128/277 (46%), Gaps = 18/277 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++VA D+D TLL+ D  +S    E L+     GI  V +TGR +       + L  K Y
Sbjct: 22  YKLVAIDMDDTLLTYDKQISRENLEALQKAHDSGIYVVISTGRIYASAYAYSEFLGFKPY 81

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-------- 113
           +I SNGA + D   N I+   LD D+ S L  + N+N D+  + Y D   +         
Sbjct: 82  IIASNGAMIRDDKDNEIYKSVLDVDLISYLINLANEN-DLYYHFYSDKIVYSPESTSKYQ 140

Query: 114 -----NRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARW 168
                NR   E +R   E + +   +   L   + + K     +  E++  +   I+   
Sbjct: 141 KYGEWNRLYAETLRVKVEDIPKDIDFTDKL--KDNIVKFVMFDEDSEKIKRVRDIIDNNK 198

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
           GD++  + S    +E++  G++KG+ L  + + LG    + +A GD  ND EM+  AG G
Sbjct: 199 GDKLETTSSFYNNIEILNKGINKGNGLRILGEYLGVDRSEMVAIGDSENDTEMVEFAGLG 258

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             M +A ++LK       +  +N ++ V + + K  L
Sbjct: 259 VAMENAIEKLKKTAD--FITKSNMENGVAYVINKFIL 293


>UniRef50_Q0SVE4 HAD hydrolase, IIB family n=17 Tax=Clostridium RepID=Q0SVE4_CLOPS
          Length = 279

 Score =  249 bits (637), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 68/278 (24%), Positives = 117/278 (42%), Gaps = 16/278 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+  H +S   KE +K  T RG+     TGR           L +K+ 
Sbjct: 3   YKLICIDMDGTLLNNKHEISERNKEAIKKATERGVKVAVTTGRLFTSAKYYAGLLGVKTP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I+ NGA + + D   +I+   L+ D    ++ V+      +      +     +  PEE
Sbjct: 63  IISCNGAFIREKDEDKVIYESVLNEDQLDRIYNVIKKYDINMAYFNTPNTVISEKIVPEE 122

Query: 121 MRFFKEAVFQYALYEPGLLEP------------EGVSKVFFTCDSHEQLLPLEQAINA-R 167
             +           E  +               + + K     +   +L  L +A    +
Sbjct: 123 HGYKVMNKMMGESKEKVMFSEGIDFREAFKTYGKHILKAICIENDSNKLNDLFKAKEELK 182

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
             + + V  S+ +  EVM  G SKG A++ +A  L  + ++ +  GD  ND  M+  AG 
Sbjct: 183 KYEDLEVVSSSPSNFEVMNKGTSKGRAVKVLADILNINREEVMCLGDSENDLSMIEFAGL 242

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G  MG+A + LK+      +  TN +D V   + K  L
Sbjct: 243 GVAMGNAEEFLKEKAD--YITDTNENDGVAKAIEKFVL 278


>UniRef50_C3K9U8 Putative haloacid dehalogenase-like hydrolase n=1 Tax=Pseudomonas
           fluorescens SBW25 RepID=C3K9U8_PSEFS
          Length = 274

 Score =  249 bits (637), Expect = 8e-65,   Method: Composition-based stats.
 Identities = 71/266 (26%), Positives = 121/266 (45%), Gaps = 3/266 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + + SD+DGTLL PDH+LS    + ++ L   G+ F  A+GR    +  + +   I   
Sbjct: 9   IRFILSDVDGTLLHPDHSLSQRTADAVRALREAGVLFSLASGRPPKAMLHLIETFGIDVP 68

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF-MNRHRPEE 120
           +   NG  + + DG+++ AH+L  + A     + +  P++   V+ D +W   +   P E
Sbjct: 69  VAGFNGGTLINPDGSILVAHHLPAEAALVTLALFSAEPEVEVWVFADGDWLRRDPSGPME 128

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            R      +   + E      + V K+     + + L+ LE  +  +      VS S   
Sbjct: 129 PREANGLGYGPVVVESFEPYLDRVDKIVAASHNTQLLVELEARLQPKVQGLAQVSRSQPV 188

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L+V A   +KG AL+ +A  LG  ++   A GDG ND  M  +AG    MG A + +K 
Sbjct: 189 YLDVTAMLANKGEALKTLAAHLGVPMEQTAAIGDGGNDPAMFQVAGLSIAMGQAEETVKR 248

Query: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266
                 V G+N +D     + +  L+
Sbjct: 249 QAS--VVTGSNIEDGAAEAIERFILA 272


>UniRef50_C1QE38 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Brachyspira
           murdochii DSM 12563 RepID=C1QE38_9SPIR
          Length = 269

 Score =  249 bits (636), Expect = 8e-65,   Method: Composition-based stats.
 Identities = 72/263 (27%), Positives = 131/263 (49%), Gaps = 6/263 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A+DLDGT L+ +  +S Y K+  + L   GI  + +TGR    + + ++ +   +Y
Sbjct: 7   IKLIATDLDGTFLNNESEISDYNKKVFQYLMNNGIEIILSTGRPFNGMQRYKNMINNDNY 66

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            I  NGA + D +G  I+   +D   +  +  +VN    +  +VY  +++ ++       
Sbjct: 67  SIVFNGAIIADTNGKFIYNKVIDEASSRGVANLVNKYK-VYLHVYSGNKYIVSEPDFYYE 125

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           R+ ++      +     ++    SK+ F  +  E+LL L+  I + +   V+ SFS    
Sbjct: 126 RYIEKENITDTIIGLDNVDNFEFSKMVFIGE-REELLRLQSYITSHFN--VHTSFSHTNF 182

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LEV+A G++KG AL+ +  K G   ++ IAFGD  ND EM+  AG G  M +  + +K  
Sbjct: 183 LEVLANGINKGSALKWLCDKKGIKREEIIAFGDNYNDIEMIEYAGVGVAMYNGEEDVKKK 242

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
                V  +N ++ V  +L K  
Sbjct: 243 AD--YVCLSNDENGVGEFLNKFL 263


>UniRef50_C2EBE1 HAD superfamily hydrolase n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2EBE1_9LACO
          Length = 288

 Score =  248 bits (634), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 63/272 (23%), Positives = 131/272 (48%), Gaps = 10/272 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++  D+D TLL+ + T++P   E +K    +G+ F   TGR  + V    + L +K 
Sbjct: 18  MYKLIVCDMDETLLADNKTITPKTVEAIKRAVKKGVRFSPNTGRGFLSVQDDLEKLGLKD 77

Query: 61  ----YMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I++NGA +  + +  ++    +  +  ++LF +  ++P+   ++Y  DE ++  
Sbjct: 78  VSGQYVISNNGAVIVENKNNRIVKTETMKFETVNELFKLGIEHPEYCVHIYTPDELYIWN 137

Query: 116 HRPEEMRFFKEAVFQYALYEPG---LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
              EE  +    +  Y   +      L+ + ++K+ F+  S  + L L++ +   + + +
Sbjct: 138 LTDEEFAYIDGRLNDYEQPKDESIEFLKEKQITKIIFSVPSEGERLALQKYVQENF-EEM 196

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           N++FS+   +E  +    KG A   + + LG   ++ IA GD  ND  M+  AG G  + 
Sbjct: 197 NITFSSDRYIEFNSKEADKGQAALHLGELLGIKPEEIIAIGDNGNDVPMIKAAGLGVSVA 256

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +  + +K++   +     N  D V   + K  
Sbjct: 257 NGREFVKEIADYVT-EADNNHDPVAEVIEKFI 287


>UniRef50_Q2JQT8 HAD hydrolase, IIB family n=1 Tax=Synechococcus sp. JA-3-3Ab
           RepID=Q2JQT8_SYNJA
          Length = 285

 Score =  247 bits (633), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 66/267 (24%), Positives = 120/267 (44%), Gaps = 7/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGT+  P + +S   ++ ++   A G+    ATGR H    +    +     
Sbjct: 22  IRLLVLDIDGTIAGPSNQVSEPVRQAIQKAKAAGVRVAIATGRMHRSAERFHYAIGADMP 81

Query: 62  MITSNGARVHDLDGNLIFAH-NLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           + +  GA + D D      H +LD  +A +L  V+ D P +  ++Y DD+ ++    P  
Sbjct: 82  LCSYQGALIRDPDSQKTLKHWSLDWSLAEELLQVLQDQP-VGVHLYIDDQLYLRELSPLS 140

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG-DRVNVSFSTL 179
             + + +   + +  P     +  +K+    +  E L  L+ ++  R+  +++ ++ S  
Sbjct: 141 QAYAERSQVPFQMLSPAQ-HGKSPTKILAVSEDTEFLQQLQGSLRQRYSPEQIYLTRSEP 199

Query: 180 TCLEVMAGGVSKGHALEAVA-KKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
             LE     V+KG+A+  +A + LG S    +A GDG ND EML  AG G  MG+A   L
Sbjct: 200 IFLEATHAAVNKGNAVRFLAEELLGVSADQVMAIGDGDNDIEMLQYAGIGVAMGNASPAL 259

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
                   V     +D V   +    L
Sbjct: 260 LPHADW--VAPPVTEDGVAVAIETFIL 284


>UniRef50_C4FT61 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FT61_9FIRM
          Length = 269

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 72/271 (26%), Positives = 117/271 (43%), Gaps = 10/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A DLDGTLL+    +S   ++ L    ++G+  V  TGR +  +     +L +  
Sbjct: 1   MIKLIAIDLDGTLLNAQKEVSQANRQALAYAKSKGVKVVLCTGRPYFAMKHFLADLGLVD 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
            + Y++T NG  V    DG ++ ++ L        + V   N D+  NV   D  +    
Sbjct: 61  PEDYIVTFNGGMVQKAQDGQVLVSNTLGTSDVLAWYQVTQ-NLDLPINVIDADRLYEPTA 119

Query: 117 RPE-EMRFFKEAVFQYALYEPG--LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            P      + E V             +P+     F    + E L      ++  + D+  
Sbjct: 120 YPVGYPSLYLENVTNVPSVVQDYKTFDPDHAFNKFVIVTTQEHLDAQIPKLDPDFKDQYA 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V  S    LEVM  GVSKG  L  + + L  S ++ +  GD  ND  M+ +AG G  MG+
Sbjct: 180 VFKSRSFFLEVMKKGVSKGDTLAKLGELLDISPQEMMTMGDQENDLSMIELAGLGVAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           A +++K       V  TN +D V H + K  
Sbjct: 240 ATEQVK--ASAQYVSLTNEEDGVAHAIHKFI 268


>UniRef50_C3WAR4 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WAR4_FUSMR
          Length = 260

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 73/262 (27%), Positives = 128/262 (48%), Gaps = 5/262 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           + V SDLDGTLL   + +S Y   T+  L  + +NF  ATGR    V  I   L I  Y+
Sbjct: 2   KFVVSDLDGTLLHSHNIVSEYTIRTIDKLVKKNVNFAIATGRGQQGVQGILKQLGINPYL 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I +NGA ++  +G  I    + + I +++   +  N ++  + + ++ +F ++  P E  
Sbjct: 62  ICNNGANIYTPEGECILDKRIPKKIVTEILKEIRKN-NLFYSAFLNEFYFHSKDEPVE-D 119

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
           F    +F     E     P+ ++K+  + D+ + L+ L   +  ++     +  S  TC+
Sbjct: 120 FTSRPLFTEVAVEKEEDIPD-LNKIIVSDDNPKVLIELVNILKNKFSHLAEIMLSQPTCI 178

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           ++     +KG  +E +A+    +  D +AFGDG ND +ML   G   IM ++ + LKD  
Sbjct: 179 DIAPKNCTKGTGIENLARIFNLTPDDFMAFGDGENDLDMLKTVGHPVIMENSQELLKDFF 238

Query: 243 PELEVIGTNADDAVPHYLRKLY 264
               V  +N +D V  YL K +
Sbjct: 239 SN--VTLSNKEDGVARYLEKFF 258


>UniRef50_A6LB32 Haloacid dehalogenase-like hydrolase n=23 Tax=Bacteroidales
           RepID=A6LB32_PARD8
          Length = 268

 Score =  246 bits (630), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 67/269 (24%), Positives = 127/269 (47%), Gaps = 9/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  DLDGTL +    ++P+ +ETL     +G++ V A+GR    +  + + L IK Y
Sbjct: 3   YKLLVLDLDGTLTNSKKEITPFTRETLLQAQEKGLHLVLASGRPTYGIVPLAEELNIKQY 62

Query: 62  ---MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              +++ NG +V DL    ++F   L  DI   L+    +    I +   + ++ ++ H 
Sbjct: 63  GGFILSFNGGKVIDLMTDKVLFEQALPPDIVPVLYNRSKEAGLAILSY--NGKYILSEHP 120

Query: 118 PEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             +   ++  + +  +   +  L +    +         E L+PLE+ +    G R+NV 
Sbjct: 121 ENKYVQYESFLTKMKIKATDDFLRDLHQPADKCLVVGEPEMLVPLEEKLRQELGKRINVY 180

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE++  G+ K  +L  + ++     ++ IA GDG ND  M+  AG G  M +A 
Sbjct: 181 RSEAFYLELVPKGIDKAASLSRLLERTRIKQEEVIAIGDGFNDVSMIHFAGLGVAMANAQ 240

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             +K     +    TN +D V  ++++L 
Sbjct: 241 PPVKANADRITQY-TNDEDGVARFIQELL 268


>UniRef50_A1SZR3 Cof-like hydrolase n=2 Tax=Psychromonas RepID=A1SZR3_PSYIN
          Length = 263

 Score =  246 bits (628), Expect = 8e-64,   Method: Composition-based stats.
 Identities = 94/264 (35%), Positives = 147/264 (55%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++  SDLDGTLL PDH +S   +ET++     G  FV ATGRH+++   ++++L I  
Sbjct: 1   MYKIAISDLDGTLLGPDHRISVKTEETIQRWVQSGRKFVIATGRHYIEAKHLQESLNIPI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGAR+H+ +G +I   NL  +IA ++   V  +  +  N++ D  W+ N    E 
Sbjct: 61  YLITSNGARIHNKEGKIIHQQNLPSNIAQEICDTVFSDA-VQINLFTDQNWYANYPLAEL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                +A F     +   L+     K+FF  ++ E L P+   + AR+GD++N++FS   
Sbjct: 120 DGMGLDAGFNCIKADLSKLDKSNTIKIFFYAEA-ELLQPVYDLLAARYGDKINLTFSLTK 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM    +KG A++ V K+    + D IAFGDGMND EML    K  +M +A   LK+
Sbjct: 179 CLEVMCANTNKGEAVKVVLKRKSLEISDAIAFGDGMNDLEMLLAVAKPIVMANAQYALKE 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
             P +E   ++ +  V   + +  
Sbjct: 239 ALPNVEKTLSSKEHGVAVIMERYL 262


>UniRef50_D0BNB6 Phosphatase YidA n=2 Tax=Granulicatella RepID=D0BNB6_9LACT
          Length = 274

 Score =  246 bits (628), Expect = 9e-64,   Method: Composition-based stats.
 Identities = 61/272 (22%), Positives = 112/272 (41%), Gaps = 9/272 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A D+DGTL++  H ++P     L     +G+  V  TGR    V    + L +  
Sbjct: 1   MIKLIAIDIDGTLINSKHEITPRVHAALTKAKEQGVYVVLCTGRPLPGVQGYLNELNLIN 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
            + ++IT NG+ V     G  +    +  D    L    +    +  +   +   ++   
Sbjct: 61  DRDFVITYNGSLVQKTGTGESLVRFGMTMDDL-KLMDDYHQQYGVHYHAIDEKNIYVTTP 119

Query: 117 RPEEMRFFKEAVFQYALYEP--GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
              +  + +  +    + +      +P          D  E L  L   ++  + +  N+
Sbjct: 120 DIGKYSYMERDLVGMPIVQQPLDQFDPNATFSKMMFVDEPEILENLIPNLSDSFKENHNI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LEV+    SKGHA+  +A+ LG    + +  GD  ND +M+  AG G  MG+A
Sbjct: 180 VRSMPVYLEVLHPQASKGHAVAKLAELLGLDASEVMCIGDQGNDRDMIEYAGMGVAMGNA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              +K+L     +  TN +D V   +    L+
Sbjct: 240 IDEIKELAN--FITTTNDEDGVAVAVETHVLN 269


>UniRef50_B0ADP8 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0ADP8_9CLOT
          Length = 273

 Score =  246 bits (628), Expect = 9e-64,   Method: Composition-based stats.
 Identities = 69/274 (25%), Positives = 130/274 (47%), Gaps = 16/274 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ SD+DGTLL  +H ++   K  L     +G+  V A+GR +    +  D L+I + 
Sbjct: 3   YKLIVSDMDGTLLGDNHKITEENKIALSKALEKGVKIVPASGRIYNSAREHFDFLDINTP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I  NGA + +     LI+ +N+  DI   +  +   N ++   +Y ++         E+
Sbjct: 63  LIACNGAIIKETKTNKLIYKNNIPNDICLKIIDIFEKN-EVYYQLYSENTMMCKNLSKED 121

Query: 121 MRFFKEAVFQYALYEPGL---------LEPEGVSKVFFTCD-SHEQLLPLEQAINARWGD 170
            R  KE +  +   +  +         +    + K+    D   ++L  +++ ++    +
Sbjct: 122 QRQTKERLKNFFNDDINVHFGDDLKEEVIKHKILKIIAIDDYDMDKLKKVKEDLDQI--E 179

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + ++ S    +E+M  GV+KG AL+A+   LG    + IAFGD  ND  ML +AG G +
Sbjct: 180 DIEITSSWFNNVEIMHKGVNKGEALKALINYLGIDKDEVIAFGDNYNDLPMLELAGIGVV 239

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           MG+A+  +K+      +   N +D V   + K  
Sbjct: 240 MGNANDEVKE--KGDYITAKNTEDGVAKAIYKFL 271


>UniRef50_C9R7C9 Cof protein n=1 Tax=Aggregatibacter actinomycetemcomitans D11S-1
           RepID=C9R7C9_AGGAD
          Length = 391

 Score =  245 bits (627), Expect = 9e-64,   Method: Composition-based stats.
 Identities = 63/263 (23%), Positives = 118/263 (44%), Gaps = 6/263 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V SD+DGTLL+  H ++   ++ +K +  RGI F+  + R    +    + L  +  
Sbjct: 133 YKAVFSDIDGTLLNNQHQITLKTEDAIKNMLKRGIPFIPVSARPPYAITPYTEQLGAQHG 192

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           MI  +GA + D +   +++  L+      L  ++ D   +  + Y   +WF N    + +
Sbjct: 193 MICYSGALILDKNLTALYSVILEPQDLQKLNELLADFAHLSISYYAGLDWFCNDVNNDWI 252

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           +         A   P  L    V K+    D+ +++  +E  +     + +++  S    
Sbjct: 253 KQESAITGLTAAAMPDNLTE--VHKLLIMGDA-DEIQAVEPVLKQALPN-LSIHRSKNEY 308

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+M    +K  A++ + + LG +    IAFGD  ND +ML  AG    MG+A   +K  
Sbjct: 309 LEIMNAAATKAKAIQFMEQYLGITADQVIAFGDNFNDLDMLQYAGLSVAMGNAPDAVKQA 368

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
               EV   N +  +   L +++
Sbjct: 369 AK--EVTANNNEGGIALVLNRVF 389


>UniRef50_B1L8F5 Cof-like hydrolase n=6 Tax=Thermotogaceae RepID=B1L8F5_THESQ
          Length = 268

 Score =  245 bits (627), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 76/267 (28%), Positives = 128/267 (47%), Gaps = 10/267 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDN-LEIK 59
           MY+V   DLDGTLL+    +S   ++ ++ L +R  + VFA+GR  V    +        
Sbjct: 1   MYRVFVFDLDGTLLNDSLEISEKDRKVIERL-SRNCHVVFASGRMLVSTLNVEKKYFGRT 59

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
              I  NGA V+  +  +I    +  ++A D+   V    ++    Y DD  +  +   E
Sbjct: 60  FPTIAYNGAMVYIPEEGVILNEKIPPEVAKDIVEYVKQF-NVHWQAYIDDVLYSEKDNEE 118

Query: 120 EMRFFKEAVFQYALYEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
              + K +  +Y + EP LLE     G +K+    D+ E+L  L++ +  ++ + V V  
Sbjct: 119 IRGYAKHSSVEYRV-EPKLLELVSKVGTTKILLI-DTPEKLDELKKILLEKFNNVVKVFK 176

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S  T LE++   V KG AL  + +++G+  ++ + FGD  ND  M   AG    MG+A  
Sbjct: 177 SFPTYLEIVPENVDKGKALRFLRERMGWKKEEIVVFGDNENDLFMFEEAGLRVAMGNAID 236

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKL 263
           ++K+      V  TN D  V H L ++
Sbjct: 237 KVKEAAD--VVTLTNNDSGVSHVLERI 261


>UniRef50_Q1QY75 Cof protein n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QY75_CHRSD
          Length = 266

 Score =  245 bits (627), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 89/261 (34%), Positives = 137/261 (52%), Gaps = 2/261 (0%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++ +DLD TLL+ +H L     ET + L ARG +   A+GRH  D+   R  L + +Y++
Sbjct: 5   LIVTDLDNTLLNAEHDLDELTIETFQALAARGHHLALASGRHFHDITAFRRRLGVPAYIM 64

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRF 123
           ++NGA ++  D +LI    +  ++   L  +     DI  N+Y  +EW ++   PE    
Sbjct: 65  STNGAHLYGPDDSLIAEQWVPAELVRALVELPR-GADIRLNLYTGEEWLIDASAPELKAL 123

Query: 124 FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLE 183
                F Y + +    +  GV KV    D  E L  LEQ+I    G R+++++S    LE
Sbjct: 124 HAHTGFHYRVADLEAHDGRGVGKVLCIGDP-EALAALEQSITETLGTRLHMTYSMAHSLE 182

Query: 184 VMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHP 243
           +MA GV+KG  LE +   LG     C+AFGD +NDAEML++AG G +M +AH  L    P
Sbjct: 183 IMAEGVNKGATLERLLAHLGLPAARCLAFGDNLNDAEMLALAGHGFVMENAHPDLPRRVP 242

Query: 244 ELEVIGTNADDAVPHYLRKLY 264
           +   IG +  + V   LR  +
Sbjct: 243 DAIRIGHHHPNGVAWQLRDFF 263


>UniRef50_C6PXU7 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PXU7_9CLOT
          Length = 272

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 72/274 (26%), Positives = 133/274 (48%), Gaps = 15/274 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+    D+DGTLL+    +S   +E LK + + G+  + A+GR  + +      LE+   
Sbjct: 4   YKWCVCDMDGTLLNSQSIISEENEEALKKIKSEGMEVIIASGRTDLMINCFVKQLELTGP 63

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I+SNG  + D+  G ++++  +++  A ++     +N +I   +Y  D+ + N+  P  
Sbjct: 64  VISSNGGLIRDMKTGKILYSKLIEKSAAEEILSYCCEN-NIDFLIYSFDKVYSNKGNPLG 122

Query: 121 MRFFKEAV---------FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
           +++ K +           +Y       ++   V K+   C  HE+++ LE+  +     +
Sbjct: 123 IKYEKLSKDPFQKMKVPVEYLENAVRSIKNINVIKILLVCSEHERVIELEKHFSK--NKQ 180

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           +    S    L++MA  VSKG+AL+ +A+ +   LK+ IAFGD  ND EML   G    M
Sbjct: 181 ITAVSSAKGLLDIMAPNVSKGNALKFLAENMDMDLKNVIAFGDNYNDMEMLKCVGMPIAM 240

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +A Q LK       V  +N +  + + + K  L
Sbjct: 241 ENAVQDLKLQAKH--VTKSNNESGIAYAINKFVL 272


>UniRef50_C2H930 Haloacid dehalogenase (HAD) superfamily hydrolase n=12
           Tax=Enterococcus faecium RepID=C2H930_ENTFC
          Length = 269

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 9/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M ++VA DLDGTLL+    +S   K+ L     +G+  V  TGR    +      L +  
Sbjct: 1   MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGRPLAAMAHYLQELGLVD 60

Query: 59  -KSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NG  V   D G ++    ++      L+ +     D+  +V  D+       
Sbjct: 61  EGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQ-QLDLPLDVLSDNVVLQLPS 119

Query: 117 RPEEMRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
            P +   +     + Q+   +   +  E V          E+L P  + I   + +   +
Sbjct: 120 APRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQEELDPKIKEIPVEFHEMYEI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             +    LE M  GV+K + +  +AK LG   ++ +A GD  ND  M+  AG G  M +A
Sbjct: 180 IKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIGDEENDLPMIQYAGLGVAMENA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
              +K+    + V  +N ++ V   ++K  L
Sbjct: 240 VPFVKEAADFVTV--SNEENGVAKVIQKFVL 268


>UniRef50_B8FYX3 Cof-like hydrolase n=2 Tax=Desulfitobacterium hafniense
           RepID=B8FYX3_DESHD
          Length = 270

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 61/249 (24%), Positives = 109/249 (43%), Gaps = 8/249 (3%)

Query: 21  SPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNGARVHDL-DGNLIF 79
           S    E ++    +G+   FATGR  V      + L +   +IT NGA + +     +++
Sbjct: 22  SERVVEAIRQARGQGVYVTFATGRMPVSARPYAEQLGLDVPIITYNGAMIQEAISREILY 81

Query: 80  AHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLL 139
              +   +A ++ G +        ++YR D  F+ +       + ++        +   +
Sbjct: 82  RKVIPVALAREVVGFLL-GEGAHLHMYRKDRVFVQKMNEWSRSYGQKTKVTVEEADLITI 140

Query: 140 ---EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALE 196
              E EGV K+       E+L    Q +  R   R++++ S    LE+    V+KG+ L 
Sbjct: 141 LEDEKEGVEKIIVFG-PPEELADWRQKLGQRLPGRLHLTSSKSYFLEMGHPEVNKGNTLL 199

Query: 197 AVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAV 256
             A+ LG   ++ +A GD +ND EM+  AG G  MG+A   +KD      V  +N +D V
Sbjct: 200 TFAQGLGIKPEEVMAIGDSLNDLEMIRCAGLGVAMGNALPEVKDAAD--VVTASNEEDGV 257

Query: 257 PHYLRKLYL 265
              + +  L
Sbjct: 258 AKAIEEYVL 266


>UniRef50_A0AEX0 Complete genome n=17 Tax=Listeria RepID=A0AEX0_LISW6
          Length = 270

 Score =  244 bits (624), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 69/273 (25%), Positives = 129/273 (47%), Gaps = 11/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY+++A D+DGTLL+  H ++P  ++++K    +G+  V  TGR    + +    L++  
Sbjct: 1   MYKIIAIDIDGTLLNDAHKITPAVRDSIKAAKEKGVKVVLCTGRPLAGIKKSLIELDLLE 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NGA V +      +    L++    +++   +   ++    +     ++   
Sbjct: 61  AGDYAITFNGAVVLETASEKTLADITLNKAELEEIYAFCHA-ENVNVTYFDGKNMYVPSR 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEG---VSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
           +  E+      + Q  LY   + E      VSK+    DS E++  + + +     ++  
Sbjct: 120 KITEITCQDSLLLQTPLYHLPVEEAPDSIHVSKIMLL-DSPEKITDVIKKLPDTIKEKFY 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V  S    LE +  GV+KG AL ++A KLG    + ++ GD  ND  M+  AG G  MG+
Sbjct: 179 VVRSVPYNLEFLQKGVNKGSALASLASKLGVKQSEVMSIGDQENDTTMIEYAGMGVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A + +K++        TN +D V + ++ L L+
Sbjct: 239 ATEHIKEIAN--YTTTTNNEDGVANAIQMLVLN 269


>UniRef50_Q38V42 Hydrolase, haloacid dehalogenase family n=2 Tax=Lactobacillales
           RepID=Q38V42_LACSS
          Length = 273

 Score =  244 bits (624), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 72/274 (26%), Positives = 112/274 (40%), Gaps = 13/274 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            ++VA D+DGTLL+ ++ LSP   E +K   A+GI  V  TGR    V      L +   
Sbjct: 3   IKLVAVDMDGTLLNENNVLSPKTIEVVKAAKAQGIKVVLCTGRPLTGVTPFLHELGLTDS 62

Query: 61  --YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+IT NGA V +   G ++  H L      +L   ++    +  +   D   +     
Sbjct: 63  SDYVITFNGALVQNTATGEILVRHTLTHAQYLEL-ETLSRTIGVHLHAEDDQFIYTANRD 121

Query: 118 PEEMRFFKEAVFQYAL---YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                  + A+    +   +   +   +  SKV    D  E L   +  I A + DR   
Sbjct: 122 ISPYTIGESALVNMPIKFRHVDEIAPDKAFSKVMLI-DDPEVLAEGKAKIPADFFDRYQF 180

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LEV+     KG+ L  +A  L     + +A GD  ND  ML+ AG    M +A
Sbjct: 181 VQSEPYFLEVLNTKAGKGNGLRDLANALNIDQSEVMAVGDQGNDLSMLAYAGLPVAMDNA 240

Query: 235 HQRLKDLHPELEVIGTNA--DDAVPHYLRKLYLS 266
              LK +     +  +N    D V + + K  L+
Sbjct: 241 IPELKKIAK--VITKSNHLGQDGVAYAIEKYALN 272


>UniRef50_C5WIM4 HAD superfamily hydrolase n=3 Tax=Streptococcus RepID=C5WIM4_STRDG
          Length = 294

 Score =  244 bits (624), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 68/272 (25%), Positives = 116/272 (42%), Gaps = 10/272 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M Q++A DLDGTLL+    +     + ++     G+  V  TGR         D L +  
Sbjct: 20  MIQLIAIDLDGTLLNEQKEIPEDNIKMIQEAANTGVKIVVCTGRPQSGTRPYFDQLGLVE 79

Query: 59  KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRH 116
           + ++I +NG   +   D  L  + +L+      L  V    P +   +  + ++ +    
Sbjct: 80  EEFLILNNGCSTYSSPDWQLRHSKSLNYSDIEALEQVSQSFPGVYLTLTGEQDYLVLEPE 139

Query: 117 RPEEMRFFKEAVF---QYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            P+ ++   + VF   Q    E      + + +  +  +    L   E A +       +
Sbjct: 140 VPDLVQADGDLVFATVQAVSLEQLSQSHQVIFQAMYLGE-KAALDAFELAASDHLRQSYH 198

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V  S    LE++  GVSK  AL  + + LG S    +A GD  ND EML+ AG G  MG+
Sbjct: 199 VVRSQDNILEILPKGVSKASALRELVEDLGLSADQVMAIGDAPNDIEMLNYAGLGVAMGN 258

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A + +K L  ++ V  TN +  V   + +  L
Sbjct: 259 ASEAIKRLADQVTV--TNDEAGVAQAIHQFVL 288


>UniRef50_B8CYJ2 Cof-like hydrolase n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYJ2_HALOH
          Length = 267

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 73/266 (27%), Positives = 120/266 (45%), Gaps = 5/266 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++VA DLDGTL+  +  LS    + +  L  RG+  V ATGR  +        L IK  
Sbjct: 4   YRMVAMDLDGTLIDENQNLSQVTIDVITELMNRGVICVIATGRMFISALPYVRKLGIKKP 63

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NGA + D     ++    +  ++A  +  +  +  +   N+Y DD   + R   E 
Sbjct: 64  VITYNGAFIKDPVTNKVLHHKPIPLNLAGQVIKITEEYGN-HINLYEDDRLLVARRNEET 122

Query: 121 MRFFKEAVFQYALYEP-GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
           + +   A  +     P      +  +K+       ++   + + I  +  D + V+ S  
Sbjct: 123 LLYEDIAGVKAREVGPLSDYLGKPPTKLLIIERDRDKYEAIYREIRLQLEDDLAVTRSRD 182

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +E+M   +SKG ALE VA      L   IA GD  ND EM+  AG G  MG++ +++K
Sbjct: 183 IFIEIMGKEISKGKALEKVASGFEIPLSQVIAIGDSWNDLEMIKAAGLGVAMGNSPEQIK 242

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
                  V  +N ++ V   L K+ L
Sbjct: 243 AEADL--VTLSNKENGVARILEKVLL 266


>UniRef50_Q7NXV0 Putative uncharacterized protein n=1 Tax=Chromobacterium violaceum
           RepID=Q7NXV0_CHRVO
          Length = 269

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 95/264 (35%), Positives = 134/264 (50%), Gaps = 9/264 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ SDLDGTLL  D  L+   +  L+   ARG+    ATGRH   V ++         +
Sbjct: 12  RLIVSDLDGTLLDKDARLADETRAALQAAVARGVALAVATGRHERQVRKLWPRDLPPVPV 71

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLF--GVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           I++NGAR+H  DG L+    L   + + L    ++ +       VYRDD       R E 
Sbjct: 72  ISANGARIHLADGTLLHQSRLSPALLARLLRPELIRETE---LGVYRDDCIMAYHSRREY 128

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             +  E      + +    + E VSKV F C + EQL  +E  I    GD V++++S + 
Sbjct: 129 SHYTGEVT---EIEDLAGFKAEDVSKVIF-CGTPEQLKAVEADIARELGDEVSMTYSHIC 184

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LEVMA GV KG AL  +   L  + +DC AFGD +NDAEML++AG   +MG+AH  LK 
Sbjct: 185 YLEVMAPGVHKGSALRRLLDHLDIAAEDCAAFGDNLNDAEMLALAGLPHVMGNAHPELKR 244

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
             P   VIG +    V   LR L 
Sbjct: 245 RLPGAPVIGDHDQAGVARQLRALL 268


>UniRef50_P0A8Y6 Phosphatase yidA n=235 Tax=cellular organisms RepID=YIDA_ECOL6
          Length = 270

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 71/271 (26%), Positives = 111/271 (40%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            +++A D+DGTLL PDHT+SP  K  +    ARG+N V  TGR +  V      L ++  
Sbjct: 3   IKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTGRPYAGVHNYLKELHMEQP 62

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y IT NGA V    DG+ +    L  D    L  +  +      +       +     
Sbjct: 63  GDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSREVGS-HFHALDRTTLYTANRD 121

Query: 118 PEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                  +  V    L   E   ++P          D    L      I     ++  V 
Sbjct: 122 ISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEPAILDQAIARIPQEVKEKYTVL 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE++   V+KG  ++++A  LG   ++ +A GD  ND  M+  AG G  M +A 
Sbjct: 182 KSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAIGDQENDIAMIEYAGVGVAMDNAI 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K++     V  +N +D V   + K  L+
Sbjct: 242 PSVKEVAN--FVTKSNLEDGVAFAIEKYVLN 270


>UniRef50_A6P2T9 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
           ATCC 29799 RepID=A6P2T9_9BACE
          Length = 274

 Score =  244 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 75/276 (27%), Positives = 121/276 (43%), Gaps = 16/276 (5%)

Query: 1   MYQVVASDLDGTLLSPDH-TLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK 59
           M +++A D+DGTLL+ DH T+S    + L+    +GI  V ++GR    +  I D + + 
Sbjct: 1   MIKLIAMDMDGTLLNDDHATVSQRNVDALRRAAEQGIEVVISSGRPWSLLQDIADRVGVV 60

Query: 60  SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH-- 116
            YM+TSNGA V D   G  +    + ++       ++              ++   RH  
Sbjct: 61  RYMVTSNGASVLDQKTGEWLLQIGMPKEQVLKFVEILTRYHAGFEIFCEGQDYIEQRHME 120

Query: 117 -------RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
                   PE +  FK  V       P ++E + V K++           +E+ + A   
Sbjct: 121 TVVREALSPEYVDTFKRRVVVVDDLRP-IIEEKLVEKIYVFYVEPGTREKIEEELRAAGP 179

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
                ++S    +E+ A GV KG AL+ + +KLG    + +AFGD  ND  MLS AG   
Sbjct: 180 YESACAYS--FNMEITAPGVDKGEALKVLCEKLGIDASEVMAFGDADNDLGMLSWAGWSF 237

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            MG+   + K       V G N+D  V   + +  L
Sbjct: 238 AMGNGTDKAKAAAK--YVTGRNSDSGVAQGVEQYAL 271


>UniRef50_C6JK34 Hydrolase n=2 Tax=Fusobacterium RepID=C6JK34_FUSVA
          Length = 258

 Score =  243 bits (622), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 69/262 (26%), Positives = 129/262 (49%), Gaps = 7/262 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V SDLDGTLL     ++ Y K  +K L   GI F  ATGR      +++ ++ +  Y+
Sbjct: 2   KLVVSDLDGTLLDTKSQITDYTKSIIKKLVNNGIEFAIATGRGPASAIKLKKDIGLDIYL 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I +NGA ++D   N IF   +D+ I+ ++  ++ D   +  N + DD+++    R E  +
Sbjct: 62  ICNNGANIYDKKENSIFEKVIDKKISQNIIKLLRDRK-VAYNGFIDDDFY----RDEYDK 116

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
                   +  +  G +E           +  + +L + + +  ++ + V ++ S   C+
Sbjct: 117 TDYSRRTDFIEHILGDIEECPALHKIIIVEEADIILRINKELREKFSNVVEITISDPECI 176

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +++    SKG+AL+ +A++LG  ++  +AFGDG ND +ML   G    M +A   +K   
Sbjct: 177 DIVPKECSKGNALKIIAQQLGIEMERVMAFGDGENDLDMLKKVGHPVAMENAQDIVKKEI 236

Query: 243 PELEVIGTNADDAVPHYLRKLY 264
                   N ++ V  YL K +
Sbjct: 237 NN--TAPKNIENGVALYLEKFF 256


>UniRef50_Q5XD45 Putative hydrolase M6_Spy0533 n=25 Tax=Streptococcaceae
           RepID=Y533_STRP6
          Length = 269

 Score =  242 bits (620), Expect = 7e-63,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 121/271 (44%), Gaps = 10/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            ++VA D+DGTLL+ D  ++    + ++   A+G++ V ATGR    V  + + LE+   
Sbjct: 3   IKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATGRPIAGVISLLEQLELNHK 62

Query: 60  -SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
            +++IT NG  V D + G  I    +  D   +    ++    +  +    +  +     
Sbjct: 63  GNHVITFNGGLVQDAETGEEIVKELMTYDDYLET-EFLSRKLGVHMHAITKEGIYTANRN 121

Query: 118 PEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             +    +  +    ++   P  +  + + K+    D  + L    + I   + D+  + 
Sbjct: 122 IGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMI-DEPDLLDAAIKQIPQHFFDKYTIV 180

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            ST   LE M   VSKG+A++ +AKKLG  +   +A GD  ND  ML +     +M +  
Sbjct: 181 KSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIGDAENDRAMLEVVANPVVMENGV 240

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             LK +     +  +N D  V H +RK  L+
Sbjct: 241 PELKKIAK--YITKSNNDSGVAHAIRKWVLN 269


>UniRef50_B9DT57 Putative haloacid dehalogenase-like hydrolase n=2 Tax=Streptococcus
           RepID=B9DT57_STRU0
          Length = 266

 Score =  242 bits (619), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 76/269 (28%), Positives = 126/269 (46%), Gaps = 7/269 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  ++ SD+DGTLL+  H +S   K  +K    +GI FV  + R    +  I  +   + 
Sbjct: 1   MVSIIFSDIDGTLLNDQHEVSSRTKTAIKECLRKGILFVPVSARMPKAIKPITCSFLPEI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDN-PDIITNVYRDDEWFMNRHRPE 119
            +I+ NGA V D  G  I +  +  D+A  +   V +   DI+ N+Y  +EW       +
Sbjct: 61  PIISYNGAFVQDKTGYPISSSPMPFDVALSICSTVEEQFNDIVWNIYSGEEWISQDRDNK 120

Query: 120 EMRFFKE--AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
            ++  +E  +V    +    +     + K+    +    +   E+     + D ++++ S
Sbjct: 121 WVKREEEIVSVTSIQMALETISHSLTIHKLLLMGEP-GSIAKAERLFKENYSD-LSIAQS 178

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LE+MA G++KG A+  +A   G  L D IAFGD  ND +ML   GKG +MG+A   
Sbjct: 179 YPYYLEIMASGITKGKAVTELATSYGVELGDTIAFGDNFNDLDMLQTVGKGYVMGNAPTD 238

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           LK L    +V   N  D +   L +  L+
Sbjct: 239 LKSL--IGDVTTDNNHDGIAEVLERTILT 265


>UniRef50_C9LAG7 HAD hydrolase, IIB family n=1 Tax=Blautia hansenii DSM 20583
           RepID=C9LAG7_RUMHA
          Length = 268

 Score =  242 bits (619), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 64/275 (23%), Positives = 114/275 (41%), Gaps = 21/275 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++  D+DGT+ +    ++   K  +  L  RGI    A+GR    +  +   LE+   
Sbjct: 3   YKLLVLDIDGTVTNSKKEVTEKTKNAILDLQKRGIPVAIASGRAPQGIYSVAKALELDKF 62

Query: 60  -SYMITSNGARVHDLD-GNLIFAHNLD--------RDIASDLFGVVNDNPDIITNVYRDD 109
            SY++  NGAR+ +   G  I++  L         RD   +  G+V  +   +    + D
Sbjct: 63  GSYIMPFNGARIVNFQTGECIYSKTLPLHLPARLWRDAVENGIGIVTYDEKEVIAGTKPD 122

Query: 110 EWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
           ++ +   +   M       F   +  P       V+K   T +  E L  LE     ++ 
Sbjct: 123 KYTLLEAKIASMPIAYHEDFHTYVDFP-------VNKCLMTGEP-EDLEALEPVFAQKYF 174

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
               +  S    LE     V K + L+ + + LG   ++ I  GDG ND  M+  AG G 
Sbjct: 175 HEAQIFRSEPYFLEATPKNVDKAYCLKHLLEILGIKREEMICCGDGFNDISMIQYAGLGV 234

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            M +A +++K +   + V   N  D +   + K +
Sbjct: 235 AMANAQEQVKAVADYVTVCD-NDHDGIAEVIEKFF 268


>UniRef50_A6LB33 Haloacid dehalogenase-like hydrolase n=34 Tax=Bacteria
           RepID=A6LB33_PARD8
          Length = 410

 Score =  242 bits (618), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 69/273 (25%), Positives = 115/273 (42%), Gaps = 13/273 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+    ++P     L      G++ V A+GR    V  + + LE+  Y
Sbjct: 3   YKLLVLDVDGTLLNDKKEITPRTHAALLKAQQMGVHVVLASGRPTNGVQPLAEALELNHY 62

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              +++ NG ++ +   G L+F   +D  +   L     +N   I   ++D   ++    
Sbjct: 63  GGFILSYNGGQIINAQTGELMFEKRIDPAMIPYLNRKAKENGFAIFTYHKD---YILTDS 119

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVS----KVFFTCDSHEQLLPLEQAINARWGDRVN 173
           PE     +EA             PE V     K   T D    L+ LE     R    + 
Sbjct: 120 PENKHVQEEAELNKMRIIGVENFPEAVDFAPCKCILTSDDENNLVGLENHWKKRLDGVLE 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              S    LEV    ++KG+ L  + + L  + ++ +A GDG+ D  ML +AG G  MG+
Sbjct: 180 AFRSEDYFLEVAPHFINKGNTLAVLMEMLNITTEEVVAIGDGVADVSMLQLAGTGVAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A   +K          +N  D V   + K  L+
Sbjct: 240 ARDSVKACAD--FTTLSNNMDGVAVAIEKAILA 270


>UniRef50_C6K3T2 Haloacid dehalogenase-like hydrolase-like protein n=1 Tax=Crithidia
           sp. ATCC 30255 RepID=C6K3T2_9TRYP
          Length = 292

 Score =  241 bits (616), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 91/290 (31%), Positives = 144/290 (49%), Gaps = 26/290 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-S 60
            + V  D+DGTLL+P+H +S Y  + L+ +  + I F+ ATGR + +V        ++  
Sbjct: 3   IKAVFVDMDGTLLNPNHEISDYTADVLRRVKEKKIRFIVATGRPYGEVIATIRRCRLEPD 62

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFG--------------------VVNDNPD 100
           Y+ITSNG R+HD   N++  HN+  ++A+ L                      + N    
Sbjct: 63  YVITSNGGRIHDGSFNVVREHNIPVELATQLVKMGNSSAASDAPETTDKAEGKLTNTKKK 122

Query: 101 IITNVYRDDEWFMNRHRPEEMRFFKE----AVFQYALYEPGLLEPEGVSKVFFTCDSHEQ 156
           I+TNVYR  EW  +   PE      +          LYE    +  GV +V++  ++ + 
Sbjct: 123 IVTNVYRHTEWLTDEDVPELSGAMHKNLPCTDLGDRLYELTPQDLVGVHQVWYYGETAD- 181

Query: 157 LLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGM 216
           L+ L   +   +G ++  +FS    ++     V+KG+ +  VA  LG +L+D   FGD M
Sbjct: 182 LVVLNDELTRAFGPQLCWTFSAPNMIDCGPVAVTKGNGVREVADVLGLALEDVACFGDAM 241

Query: 217 NDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           ND  ML +AGK  IM +A   LKD     EVI +NA+D V   L +L+L+
Sbjct: 242 NDESMLQIAGKAYIMANAQPSLKDAVEHGEVIESNANDGVAKKLEELFLA 291


>UniRef50_A4BEF7 Hydrolase, haloacid dehalogenase-like family protein n=3
           Tax=Bacteria RepID=A4BEF7_9GAMM
          Length = 314

 Score =  241 bits (615), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 63/266 (23%), Positives = 105/266 (39%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            +++  D+D TLL+  H +S    + ++ ++A+GI    A+GR    +    D L +   
Sbjct: 45  IRMIVMDMDDTLLNDQHQISESNLQAIQRVSAQGITIALASGRPTPAMESYADLLGLTQQ 104

Query: 60  SYMITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y+I+ NGA V D      I+  +L +     L    ++  +   + Y D      RH P
Sbjct: 105 GYVISYNGAYVTDWSTQEQIYECSLTKAECDLLVDAAHEQ-NSDLHTYVDGAIVTTRHNP 163

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
                         L +      +G           EQ+  + Q      GD   +S S 
Sbjct: 164 YTDIESNLTGLPIRLVDSLKAVVQGTVPKVLLVAPPEQVTEMRQIFAKTLGDHFTISISK 223

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LE     V K  A++ +  +LG +    +A GD  ND  ML+  G G  MG+A   +
Sbjct: 224 PYFLEFTNKQVDKSAAIDVLCARLGIAKSSVMAIGDSYNDLTMLTDCGIGVAMGNAPDDI 283

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           K +        +N D  V   + K+ 
Sbjct: 284 KAIANW--TTASNNDHGVALVIDKIL 307


>UniRef50_Q8ENE7 Hypothetical conserved protein n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8ENE7_OCEIH
          Length = 246

 Score =  240 bits (614), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 62/263 (23%), Positives = 124/263 (47%), Gaps = 24/263 (9%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGTLL+P+H +S   K+ ++    +GI+ + +TGR         + L + SY+
Sbjct: 8   KLIALDMDGTLLTPEHEVSERNKKAIQTALEQGIDVILSTGRSWDTCFPFAEELSLTSYL 67

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           IT+NG ++  ++  L+  H L  +    ++ +  +  ++   +   ++ F          
Sbjct: 68  ITANGGQIWTVEKELLQQHLLKTETVEKMYLLAKEK-NMHCWMISTEKVF---------- 116

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
                      + P  L      K     +   +L  + + ++  + D + ++ S  T +
Sbjct: 117 ---------RGHAPDNLYDHQWLKFGCASEDKNKLDQMIKELS--YNDELELTNSLPTNI 165

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           E+   GVSK  AL+ + +K+G ++ + +A GD +ND +M+  AG G  MG+A   +K + 
Sbjct: 166 EINPKGVSKAQALQFLCEKIGITMDNVMAVGDSLNDIKMIQEAGVGVAMGNAQVAIKKVA 225

Query: 243 PELEVIGTNADDAVPHYLRKLYL 265
                  TN +D V   + K  L
Sbjct: 226 N--YTTDTNEEDGVGIAIEKYAL 246


>UniRef50_C9AY54 HAD-superfamily hydrolase n=4 Tax=Enterococcus RepID=C9AY54_ENTCA
          Length = 272

 Score =  240 bits (614), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 64/271 (23%), Positives = 112/271 (41%), Gaps = 9/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           M +++A DLDGTLL+    ++P  KE L    A+G+  V  TGR    +    + L +K 
Sbjct: 1   MIKLIAIDLDGTLLNDKKEVTPRNKEVLARAKAQGVKIVICTGRPLRAIRPYLEELSLKE 60

Query: 60  --SYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NG  V  +  G +I    +      +L  V  D  ++  +V  ++       
Sbjct: 61  PGDYSITFNGGLVQKNETGEIIEKAAMQLADIHELVSVAED-LNLPLDVVSEEIVLSLPT 119

Query: 117 RPEEMRFFKEA--VFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                  +     +     +    L+   +          E L P    I++   ++  +
Sbjct: 120 SAAHPSIYGSLNPLLDCRPFAVADLDESMLYNKAVIAYHQEVLDPKIPEISSEIREKYEI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LE M  G++K + +  +A+ LG   ++ +A GD  ND  M+  AG G  M +A
Sbjct: 180 IKSRNNLLEFMPKGITKAYGISLLAQDLGIKQEEVMAIGDEENDLPMIRYAGIGVAMANA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
              +K+    + V  +N +D V   + +  L
Sbjct: 240 VPIIKEAADVVTV--SNQEDGVAAVIEEYVL 268


>UniRef50_Q0TQ35 HAD hydrolase, IIB family n=9 Tax=Clostridium perfringens
           RepID=Q0TQ35_CLOP1
          Length = 276

 Score =  240 bits (613), Expect = 4e-62,   Method: Composition-based stats.
 Identities = 76/277 (27%), Positives = 124/277 (44%), Gaps = 17/277 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V  D+DGTLL   H +S   KE LK    +G++   +TGR         + + + + 
Sbjct: 3   YKLVCIDMDGTLLDSHHKVSERNKEALKKAIEKGVHIAISTGRVFPSARIYGNIIGVNAP 62

Query: 62  MITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I SNG+ + D +   +IF   LDR+    +  ++N     +  V   D    +   PE+
Sbjct: 63  LICSNGSYIKDKNTDEVIFKSTLDRETYFKICDIINKYK-FLAYVDSTDGLIADTDIPED 121

Query: 121 -----MRFFKEAVFQYALYEPGLLEP------EGVSK-VFFTCDSHEQLLPLEQAINARW 168
                M  + +   +   Y    L        E + K +    +    +   ++   A  
Sbjct: 122 DSHRLMNSWVDEKEKIKFYNCDDLRDAYDEHGEDILKFIIIKQEGGPNIEEAKEEFEALE 181

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
           G  + V  S   C+E+M  G SKG A++A+A KLG SL++ I  GD  ND  ML  AG  
Sbjct: 182 GVDL-VYASWGGCIEIMKKGTSKGSAVKALADKLGISLEEVICIGDSGNDVSMLEEAGLS 240

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +MG+A   +K+      +  TN +D V   + K  L
Sbjct: 241 VVMGNAPDFIKEYGD--YITDTNENDGVAKAIEKFIL 275


>UniRef50_UPI0001C365F0 putative haloacid dehalogenase-like hydrolase n=1 Tax=Clostridium
           hathewayi DSM 13479 RepID=UPI0001C365F0
          Length = 299

 Score =  239 bits (612), Expect = 5e-62,   Method: Composition-based stats.
 Identities = 70/270 (25%), Positives = 113/270 (41%), Gaps = 8/270 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++  DLDGTL + D  ++P  KE L  L ++G   V A+GR    +  +   L +   
Sbjct: 33  YRMIVLDLDGTLTNRDKVITPRTKEALMKLKSQGGTIVLASGRPTYGIMPLARELGLTED 92

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NG R+ +   G  +FA  L       +  +  ++  +    Y  D        
Sbjct: 93  GGYILSFNGGRIIECRSGETVFAKELPVASNKKIIALAKEH-GVNILTYEGDCIITPDSG 151

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKV-FFTCDSHEQLLPLEQAINARWGDRVNVSF 176
              ++   +             E      V F   D  + L  +E  + A  G   +V  
Sbjct: 152 DIYVKKESDINKLEVRKVENFAEYVDFPVVKFLLLDDGDYLALVEPKVKAALGRDYSVYR 211

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LEV+  G+ K  +LE +  +L  +  + IA GDG ND  M+  AG G  M +A  
Sbjct: 212 SEPYFLEVLPKGIDKAASLERLLTRLDMTKDEMIACGDGYNDLSMIQYAGLGVAMENAVL 271

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +K+      V  +N DD V H + K  LS
Sbjct: 272 PVKNAAD--YVTLSNNDDGVAHVIEKFMLS 299


>UniRef50_C7N949 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7N949_LEPBD
          Length = 274

 Score =  239 bits (612), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 75/277 (27%), Positives = 113/277 (40%), Gaps = 16/277 (5%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A D+DGTLL+    +    KE +      GI  V  TGR    +      L +  
Sbjct: 1   MIKLIAIDMDGTLLNEKKHIEKAQKEAIHEAIEAGIKIVLCTGRPLYGILPFYKELGLQE 60

Query: 59  ---KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN 114
              + Y+I +NG  VH   D  LI    +  D    L+          T V  D+  + N
Sbjct: 61  LDQEGYVILNNGCSVHKTKDWELIECAEITPDDMEHLYKFSEKYDINFTLV--DETHYFN 118

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPEG-----VSKVFFTCDSHEQLLPLEQAINARWG 169
             R        +A F ++      LE        + KV F  D  E +   +        
Sbjct: 119 IGRKPTKELIMDAQFVFSDITDITLEEAKSGKYKIVKVMFLGDPEE-MKKFQTEYEDMIK 177

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           +R     S     EV+  G +KG  L+ +A+KLG   ++ +A GDG ND EML  A  G 
Sbjct: 178 ERYEGVLSQSYVYEVLPKGYNKGTGLKNLAEKLGIKQEEVMAIGDGNNDVEMLEYANYGV 237

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            MG+A +  ++         TN +D V   +RK  L+
Sbjct: 238 AMGNASKLARNAAK--YTTDTNENDGVAKAIRKYALN 272


>UniRef50_Q04GT8 Predicted hydrolase of the HAD superfamily n=2 Tax=Oenococcus oeni
           RepID=Q04GT8_OENOB
          Length = 271

 Score =  239 bits (612), Expect = 6e-62,   Method: Composition-based stats.
 Identities = 69/272 (25%), Positives = 118/272 (43%), Gaps = 11/272 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            ++VA D+D TLL+  + L+ +  +TLK   A G   V  +GR           L I   
Sbjct: 3   IKLVAIDVDATLLNSRNELTKHTIDTLKEAIAMGTKIVITSGRPLPGTEPYYAKLGIDKK 62

Query: 60  --SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y I  NGA +    G +I    L      D++ + N    +       D  +     
Sbjct: 63  DDQYAINYNGATIRTTSGRMISEATLTIKDYKDIYSLANKI-GVKIQAETADCIYTPYLS 121

Query: 118 PEEMRFFKEAVFQYALYE---PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
             +   +++ +    +       L + + ++K+ F  D  E +  +++ + A   DR NV
Sbjct: 122 APKYTKYEQKLTNAKIRHVRMQDLKKSDVIAKIMFI-DEPEIISRVKKELPAWVYDRFNV 180

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S+   +E +   VSKG+A+  +A+KLG  +   +A GD  ND  M+  AG G  MG+ 
Sbjct: 181 VPSSPVYIEFIDKKVSKGNAVRTLAEKLGIDISQVMAIGDQGNDLSMIEAAGVGVAMGNG 240

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              LK +     V  +N +D V + + K  L+
Sbjct: 241 IDDLKSIAQ--FVTKSNDEDGVAYAVEKFLLN 270


>UniRef50_Q891C8 Hydrolase (HAD superfamily) n=3 Tax=Bacteria RepID=Q891C8_CLOTE
          Length = 320

 Score =  239 bits (611), Expect = 7e-62,   Method: Composition-based stats.
 Identities = 62/269 (23%), Positives = 106/269 (39%), Gaps = 5/269 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++VA D+DGTLL    T+       +K  + +GI    ATGR    +    + L + S
Sbjct: 52  MYKLVAIDMDGTLLDDSKTIPNENIRAIKEASNKGIKIALATGRPLTGIKNYLNVLGLNS 111

Query: 61  Y---MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
                I  NGA + +     I +  L        F  ++    I  NV+  D    ++  
Sbjct: 112 PDNFSIIYNGALIQNNTNKKIISQCLLNYDDLMYFHNLSRKFHIHMNVFTKDSCITSKLG 171

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
                  K +     + +   L+           D  E +  +   ++     +  ++ S
Sbjct: 172 KYTTLEAKWSNIDVKIVDFNNLDKNIEITKVIFADEPELISKIMDNLDDDVYSKYAMARS 231

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LE     ++KG A++  A  L    ++ I  GD  ND EM+  AG G  M +A   
Sbjct: 232 APYFLEFFNKEINKGIAVKKYADSLNIHKEEIICIGDAGNDIEMIKFAGLGIAMENAFPE 291

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +K++     +  +N +  V H + K  LS
Sbjct: 292 IKNVAN--YITLSNENAGVAHAIDKFILS 318


>UniRef50_C7NEL2 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7NEL2_LEPBD
          Length = 263

 Score =  239 bits (611), Expect = 7e-62,   Method: Composition-based stats.
 Identities = 68/263 (25%), Positives = 123/263 (46%), Gaps = 4/263 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + +  DLDGT+L+ +H +S    + L+ L  +G+    ATGR  +      + LEIK+ 
Sbjct: 4   IKAIFMDLDGTVLTSEHKVSENLIKKLRELEEKGVKTFIATGRTFISSKPFVEMLEIKNP 63

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I  NG RV +  +  +IF   ++     +L  V  +   I  N+Y DD+ ++     E 
Sbjct: 64  VINYNGGRVTNPLNNEVIFEKPVEAQDVKELIKVSREK-GIHLNLYMDDKLYIENETDEG 122

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            ++ +     Y +        +  +K  F  ++   +L   +         +N  FS   
Sbjct: 123 KKYSESVEIPYYVKNFDEFIGKTSTKALFITEN--SILLELKKELEEKLPHINFVFSKPH 180

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE +   V+KG A++ + KK   S ++ +AFGD  ND EML     G +MG+A + LK 
Sbjct: 181 YLECLNKEVNKGLAIKELLKKYDISPEETMAFGDQWNDLEMLKFVKYGYLMGNATEELKQ 240

Query: 241 LHPELEVIGTNADDAVPHYLRKL 263
              + ++  +N +D +   ++ L
Sbjct: 241 EFSKDKITLSNDEDGIYEVIKAL 263


>UniRef50_B0P090 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P090_9CLOT
          Length = 298

 Score =  239 bits (611), Expect = 7e-62,   Method: Composition-based stats.
 Identities = 69/276 (25%), Positives = 126/276 (45%), Gaps = 17/276 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLD TLL  +  +S + +E LK    RG+  V ATGR    + +   ++    Y
Sbjct: 26  IKLVAMDLDNTLLDSEKQISKHTEEVLKEAIRRGVYIVPATGRIFKAIPEFLRDIPGVRY 85

Query: 62  MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            +  NGA V+D  +  +I+ ++L ++    LF ++ +      ++Y++ + +M R   + 
Sbjct: 86  AVCCNGATVYDQKENKIIYTNHLPKETVFSLFDIL-EKYHCTRDIYQNGQGYMERCYFDH 144

Query: 121 MRFFKEAVFQYALYEPGLLE-----------PEGVSKVFFTCDSHEQLLPLEQAINARWG 169
           +  +  +     L     L            P G+ K+    D  E+     Q +  +  
Sbjct: 145 LAEYGVSDHVLKLVRDTRLPLDDLRKYIEERPLGIEKINVFFDDMEERETARQELIEK-- 202

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           +  +VS S    +E+   G  KG  L  +A+++G S+ + +A GD  ND  M+   G G 
Sbjct: 203 NIASVSSSLGNNIEINQIGCDKGDGLLHLAEQIGLSMDEVMACGDAGNDTMMIKAVGTGV 262

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +M +    LK++     V  TN +D V + + KL  
Sbjct: 263 VMENGQPDLKEIAD--FVTKTNNEDGVAYAIEKLVF 296


>UniRef50_C9XMM6 Putative hydrolase n=4 Tax=Clostridium difficile RepID=C9XMM6_CLODC
          Length = 284

 Score =  239 bits (611), Expect = 7e-62,   Method: Composition-based stats.
 Identities = 72/279 (25%), Positives = 124/279 (44%), Gaps = 21/279 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ +D+DGTLL  +H ++   K  L+ +   GIN   ATGR         D L+    
Sbjct: 3   YKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATGRAFDSAKCNVDFLKEDMP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I  NG+ + + +GN+I+++ +D     ++  V+ D  DI       D     ++R   +
Sbjct: 63  IIACNGSLIREQNGNIIYSNKIDTRTCLNILDVL-DKYDIYYQCNSIDSMLYEKNRRTIL 121

Query: 122 RFFKE----------------AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAIN 165
            F K+                 V         + + + +  V     +   L  + + + 
Sbjct: 122 CFTKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPSILDEIRKELR 181

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
              G  + ++ S    +EVM  GV KG+A++ +A+K+    +D IAFGD  ND EM+  A
Sbjct: 182 KVQG--IKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDNYNDIEMIKFA 239

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G G  MG+A + +K       V  TN D  V   + K  
Sbjct: 240 GLGVAMGNAEELIKQEAD--YVTDTNQDSGVAKAIYKFL 276


>UniRef50_A9H329 Cof-like hydrolase n=1 Tax=Gluconacetobacter diazotrophicus PAl 5
           RepID=A9H329_GLUDA
          Length = 292

 Score =  239 bits (610), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 66/265 (24%), Positives = 107/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++V SD+DGTL++PD  L+P   +T + L A GI     + R    +      L I + 
Sbjct: 18  IRLVISDIDGTLVTPDKRLTPAVLDTARALRAAGIALCLVSSRPPRGMEMFLGPLGIDTP 77

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
               NG  V   DG +I   +LD D A    G++  +  +   ++   +W +       +
Sbjct: 78  RAGLNGGLVTQPDGTIISRLSLDPDAAQQAVGMLQSH-GVDAWLFVGHDWLITDPDGAYV 136

Query: 122 RFFKEAVFQYALYEPGLL-EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
              +  V    +  P        V K+      +  L  +E  I  R   R +V  S+  
Sbjct: 137 ERERRTVQTDPVVLPDFAGHYNDVGKIMGASSDYPLLARMEADIGTRLAGRASVHRSSDY 196

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L++     +KG+A   +A+ +   + D    GD  ND  ML  AG    MG+A   +K 
Sbjct: 197 YLDITHPQANKGYAALELARLMDIDIHDVACIGDMNNDIPMLDEAGVSIAMGNAPDGVK- 255

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 V  TN  D   H + +  L
Sbjct: 256 -AHAHFVTDTNEQDGWAHAMERYVL 279


>UniRef50_B0BRY2 Predicted hydrolases of the HAD superfamily n=7 Tax=Pasteurellaceae
           RepID=B0BRY2_ACTPJ
          Length = 263

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 62/268 (23%), Positives = 119/268 (44%), Gaps = 10/268 (3%)

Query: 1   MYQ----VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL 56
           M +     V SD+DGTLL+  H ++P  ++ ++ +  +GI F+  + R  + +      L
Sbjct: 1   MKKPLYLAVFSDIDGTLLNTAHQITPLTRQAIQSVMQKGIPFIPVSARPPLAITPYTQQL 60

Query: 57  EIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           +    +I  +GA + D D + +++  +++   + L  ++     +  N Y   +WF N  
Sbjct: 61  QSYYPIICYSGALILDQDLSQLYSVVIEQADLNRLDLLLEKYQHLSINHYAGIDWFTNDL 120

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             E     +E+                V K+    ++ EQ+  LE+ +  +    + +  
Sbjct: 121 ENEWT--VQESEITGLQAVEKTKNLTDVHKILVMGEA-EQIQSLEKLLKQQLP-HLAIHR 176

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE+M    +K +A+  +   L  +    IAFGD  ND +ML  AG    MG+A +
Sbjct: 177 SKNEYLEIMNKQATKSNAIRFMETILNVNQDQVIAFGDNFNDLDMLQYAGLSVAMGNAPE 236

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +K       V  +N DD +   L +++
Sbjct: 237 EIKAAAKR--VTLSNNDDGIAVVLNEIF 262


>UniRef50_A8UBX5 Putative uncharacterized protein n=1 Tax=Carnobacterium sp. AT7
           RepID=A8UBX5_9LACT
          Length = 269

 Score =  238 bits (608), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 70/273 (25%), Positives = 130/273 (47%), Gaps = 11/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A D+DGTLL+  H ++   K+ +K  +  GI  V  TGR    V    + L++  
Sbjct: 1   MIKLIAIDMDGTLLNEHHLVTDKVKKAIKEASNAGIKIVLCTGRPVHAVYDYFEELDLPK 60

Query: 59  --KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
             + Y+I+ NG  V    +  ++++H LD         ++    ++    + +  ++   
Sbjct: 61  DEEDYVISLNGTVVQKTTNWEIVYSHQLDHSQLKKAEQLIEPF-EMNFTYFDEKAYYYTG 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEG--VSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            + E ++F  + +   A++ P    PE   + K  +  +  E L  L  ++ A   +   
Sbjct: 120 KKTEMLQFDADLLGMDAVHLPLEELPEELTIFKAMYVAEETE-LDHLAASMPAFISENFY 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              S    LE++  G +KG AL  +A KLG+S+ + +A GDG ND +M+ +AG    MG+
Sbjct: 179 PIRSLSYVLELLPQGANKGEALTGLATKLGFSMDEVMAIGDGENDLDMMKVAGTSVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A   +K       V  +N +D V H + +  L+
Sbjct: 239 AVDSIKLTAK--YVSKSNQEDGVAHAIYEWALN 269


>UniRef50_A8MEY7 Cof-like hydrolase n=2 Tax=Alkaliphilus RepID=A8MEY7_ALKOO
          Length = 275

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 66/276 (23%), Positives = 119/276 (43%), Gaps = 17/276 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+ +  ++   +  LK    +GI    ATGR         + L I S 
Sbjct: 3   YKLIVLDMDGTLLNRNKEVTKENQIALKKAQEKGIKVAIATGRVFTSAKFYANMLGIDSP 62

Query: 62  MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR----- 115
           +I  NGA + +     +I+ + + ++       +   +  +  + Y +D  ++       
Sbjct: 63  IIACNGALIKEAASNEIIYTNPIRKEDLLKSLEIFRRH-QVYFHTYDEDTIYIESLGFSS 121

Query: 116 --HRPEEMRFFKEAVFQYALYEPGLL----EPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
             +        +E        E   L     P    K+    +  E++L ++  +   +G
Sbjct: 122 AIYNDWNEDQSEENKIPIKKLEDSYLYFKDNPIETLKIMAVDEDSEKMLQIKTELGEIYG 181

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
             +N   S    LEVM  GVSKG+A+E ++K  G   ++ I+FGD  ND  M S +G   
Sbjct: 182 IELN--KSWYNNLEVMNKGVSKGNAIEMLSKIYGIKREEIISFGDHFNDLSMKSYSGTFV 239

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            MG+A + +K       +  +N +  V   + KL L
Sbjct: 240 AMGNAEEAVKKEA--HYITSSNDESGVAKGIEKLVL 273


>UniRef50_C6PMT7 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PMT7_9CLOT
          Length = 267

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 72/283 (25%), Positives = 127/283 (44%), Gaps = 34/283 (12%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGTLL+ +  +S   KE ++    +G+N V  +GR    V    D + ++ 
Sbjct: 1   MYKLLAVDMDGTLLNSNRIISKANKEAIRKAVEKGVNVVITSGRGLKGVDNFLDEVHLRG 60

Query: 61  ---YMITSNGARVHDLDG------------NLIFAHNLDRDIASDLFGVVNDNPDIITNV 105
              Y+I +NG  ++                +LI AH L +    ++    ++ P      
Sbjct: 61  ENQYLIANNGGTIYRTSNFECVAYKGLRGRDLIKAHTLSKKFGLNMIAYTHEGP------ 114

Query: 106 YRDDEWFMNRHRPEEMRFFKEAV---FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQ 162
                  +     E  RF  E V    +   ++  + + + ++K+ F   + E L     
Sbjct: 115 -------IAAEESEFTRFEAEYVGTPVKIINFKSDIEDNDEITKILF-SQTEELLDKKML 166

Query: 163 AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
            +  ++    NV  +    LEVM    +KG+ ++ +A KLG   ++ +  GD  ND EML
Sbjct: 167 ELPKKFYTEYNVVKTMPIILEVMNKNCNKGYGVKVLADKLGIKKEEVMCIGDQANDVEML 226

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           + AG G  MG+A + LKD+     V   N +D V   ++K  L
Sbjct: 227 TYAGLGVAMGNAIEELKDIAQ--YVTLDNDNDGVAKAIKKFIL 267


>UniRef50_C7HV82 HAD phosphatase superfamily protein n=1 Tax=Anaerococcus vaginalis
           ATCC 51170 RepID=C7HV82_9FIRM
          Length = 278

 Score =  237 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 120/271 (44%), Gaps = 7/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTLL+    ++   K  L      G   V A+GR  + V    D LE + 
Sbjct: 8   MKKIIAVDIDGTLLNSKRQITEKTKNALIKAQELGHIVVIASGRDPLGVYPFADILEFEK 67

Query: 61  Y--MIT-SNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           Y  +I+  NG R+ +     +I  H +D D+A ++      N  +   +Y +D+   +  
Sbjct: 68  YGGLISNFNGGRITNYKTKDVIINHPMDFDLAKEILQFSEKNLFMHYIIYTEDKIITSSS 127

Query: 117 RPEEMRFF-KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           +  ++    ++A   Y + +      +              +    + +  ++ ++    
Sbjct: 128 KTYKLEEICQKAFTHYEVIDDLAYSLDFAPNKILFSQDPNLIDDDAKKLMDKFSNKTTQV 187

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            ST    E+M  G+ KG +L  +AK     +KD IAFGD  ND  M+ MAG G +M +  
Sbjct: 188 KSTPYFYEIMPKGIGKGESLVEIAKYFDMDMKDVIAFGDEENDQTMIEMAGLGVVMENGA 247

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K+      +  +N DD + +YL K   +
Sbjct: 248 NFMKEKAD--FITKSNDDDGIAYYLEKFVFN 276


>UniRef50_C6JKA3 HAD-superfamily hydrolase subfamily IIB n=3 Tax=Fusobacterium
           RepID=C6JKA3_FUSVA
          Length = 264

 Score =  237 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 70/266 (26%), Positives = 128/266 (48%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + VA DLDGTLL+ D  +S   ++ LK L  +G+     TGR +       + L +   
Sbjct: 3   IKAVALDLDGTLLTTDKKISDINRDVLKELEQQGVKIFIVTGRTYHAAKPYAEYLNLGGV 62

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH-RPE 119
           +I+ NGA+V +  +  ++F   L  +   ++  +      +  N+Y+D++W++    R E
Sbjct: 63  VISYNGAKVVEYRNDRVVFELPLQEEYVKEIIRIARKM-GVALNLYQDNKWYVEDSSRKE 121

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            + + +E        +    +   ++K  F   + + L  + + +    G++V  + S  
Sbjct: 122 VLEYARERNLIPIEKDFYSFDNYEMTKTVFMG-TPDILDKVNREVEKVLGNKVYKAKSMD 180

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           T  EV+   V+KG  LE   K  G S ++C AFGD +ND EML++   G  MG+A   +K
Sbjct: 181 TLYEVLNREVNKGLVLERTLKTYGISPEECAAFGDAVNDIEMLTVVKYGVAMGNAPHEVK 240

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
                  +  TN ++ V  +L+K + 
Sbjct: 241 SRVN--YITDTNDNNGVAKFLKKFFF 264


>UniRef50_Q1JAD8 Hydrolase n=30 Tax=Streptococcus RepID=Q1JAD8_STRPB
          Length = 293

 Score =  237 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 68/272 (25%), Positives = 113/272 (41%), Gaps = 8/272 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M Q++A DLDGTLL+ D  +       ++     G+  V  TGR         D L +  
Sbjct: 20  MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGRPQSGTRPYFDQLGLTQ 79

Query: 59  KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRH 116
           + ++I +NG   +   D  L  +  L       L  +    PDI   +  ++++ +    
Sbjct: 80  EEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFPDIYLTLTEENDYLVLEEE 139

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVF--FTCDSHEQLLPLEQAINARWGDRVNV 174
            P+ ++   + VF            +    +F          L   E+A+  +     +V
Sbjct: 140 VPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEKAALDAFERAVRNQLSQSFHV 199

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LE++  GVSK  AL+ + + LG +    +A GD  ND EML+ AG G  M +A
Sbjct: 200 VGSQDNILEILPQGVSKASALKELVEDLGLTADQVMAIGDAPNDIEMLTYAGLGVAMENA 259

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              +K L  +  V  TN    V   +R+  L+
Sbjct: 260 SAAIKPLADK--VTLTNDMAGVAQAIRQFALA 289


>UniRef50_C1I280 HAD hydrolase n=1 Tax=Clostridium sp. 7_2_43FAA RepID=C1I280_9CLOT
          Length = 280

 Score =  237 bits (606), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 71/279 (25%), Positives = 125/279 (44%), Gaps = 19/279 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGTLL+  H +S   KE LK   + G+     TGR         D + I S 
Sbjct: 5   IKLICIDMDGTLLNSKHEISERNKEALKKANSLGVKIAITTGRLFCSARYYADLIGIDSP 64

Query: 62  MITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITN-----VYRDDEW---- 111
           +I SNGA +     ++ I  + + ++IA +++ +V  +   +       + R+DE     
Sbjct: 65  VIGSNGAYIKHKYDDIAILENPIPKNIAIEIYKIVKKHGLTVNFNSWDTLIREDEVPATH 124

Query: 112 ---FMNRHRPEE--MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINA 166
               MN+  P++  ++F   +     +        +G+  V    ++ + L   +  +  
Sbjct: 125 AYTIMNKDLPDDKKVKFIVNSDVIETINNFDGKILKGI--VIEEAENKDNLWAAKDELKE 182

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
            +GDR++V  S     EVM G  SKG+A+  +A     + ++ +  GD  ND  ML  AG
Sbjct: 183 TFGDRLHVVSSGTDNFEVMVGTTSKGNAVAHLADTFNINPEEVMCIGDSENDISMLKFAG 242

Query: 227 KGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
               MG+  Q +KD+     V  TN +D V   +    L
Sbjct: 243 VSVAMGNGLQMVKDIAD--FVTDTNNNDGVAKAIEMFVL 279


>UniRef50_A4HGI1 Putative uncharacterized protein n=4 Tax=Leishmania
           RepID=A4HGI1_LEIBR
          Length = 414

 Score =  237 bits (606), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 107/320 (33%), Positives = 162/320 (50%), Gaps = 57/320 (17%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLL-TARGINFVFATGRHHVDV----------- 49
           ++ VASD+DGT+LSP HTLS Y  ETL+ L   R + F+FATGR + DV           
Sbjct: 92  FRFVASDMDGTILSPHHTLSEYTAETLRRLTQDRNVAFIFATGRVYADVAIVNQNMQRFF 151

Query: 50  GQIRDNLEI---------KSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVV-NDN 98
            + R  L             Y+ITSNGA VH+ + G L+  H LD  +  +++ ++    
Sbjct: 152 RERRQQLHPVPTTTGARTPIYIITSNGAVVHNAETGELVLEHALDPVVVREIYHLLPASE 211

Query: 99  PDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYE--PGLLEPEGV------------ 144
             I T + + D WF  R+  E + F KE+ ++Y + E  P  ++  G+            
Sbjct: 212 TRINTGIIQGDHWFYRRNWEEMLEFHKESGYRYQVLEFIPDSVDKSGIDTDTLVGSPSAL 271

Query: 145 -------SKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEA 197
                   KVFF+      L  LEQ +  R+G  + V+FS    L++ A  V+K  ALE 
Sbjct: 272 SGCLKHVHKVFFSSWDLSLLEKLEQTLQQRYGSDLTVTFSASYNLDITAKDVTKAWALER 331

Query: 198 VAKKLG---------YSLKD----CIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPE 244
           + +++           + +      +AFGD +NDA MLS AG+  IMG+ + +L+   P 
Sbjct: 332 LYEQMAPLPHETRSTVTPEQRLKATVAFGDNLNDATMLSSAGRSFIMGNCNPKLRQRCPN 391

Query: 245 LEVIGTNADDAVPHYLRKLY 264
           LEVI TNA+DAV   LR+++
Sbjct: 392 LEVIQTNAEDAVARKLREIF 411


>UniRef50_UPI000197CA00 hypothetical protein PretD1_00540 n=1 Tax=Providencia rettgeri DSM
           1131 RepID=UPI000197CA00
          Length = 270

 Score =  237 bits (606), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 71/269 (26%), Positives = 118/269 (43%), Gaps = 9/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            ++VA DLDGTLL+  H +SP  KE +     +G++ + A+GR    +      L++   
Sbjct: 3   IKLVAIDLDGTLLNSQHQISPVVKEAITQAKQKGVHIILASGRPFSGISPYLRELDLNTA 62

Query: 59  KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRH 116
            +Y I++NG+ +H   DG+ +  + LD       F  +  N  +  +   D+  F  NRH
Sbjct: 63  DNYCISNNGSVIHQANDGSHLAENLLDFADF-QYFEELARNVGVHMHALADNSMFTANRH 121

Query: 117 RPEEMRFFKEAVFQYALYEP-GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                           +Y P   ++       F   D  E+L      I     D  +++
Sbjct: 122 ISHYTVADAYLTHTPLIYCPVNEMDSSLEFTKFMIIDHPEKLDMGISYIPENVFDNYSLT 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            ++   LEV     SKG ALE + +KLG +    ++ GD  ND +ML  A     MG+A 
Sbjct: 182 RTSPYFLEVSNKTSSKGAALECICEKLGITPDKVMSIGDQNNDIQMLQYASVSVAMGNAL 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           + ++ +     V  TN +D V   + K  
Sbjct: 242 EPIRQMVK--FVTTTNDEDGVAVAINKFI 268


>UniRef50_Q5DYX0 Predicted hydrolase n=65 Tax=Bacteria RepID=Q5DYX0_VIBF1
          Length = 273

 Score =  237 bits (605), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 51/270 (18%), Positives = 105/270 (38%), Gaps = 6/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY+++A D+DGTLL+ D  +S   K  +     +G+  V A+GR    +    + L +  
Sbjct: 5   MYKLIALDMDGTLLNSDKQISAENKAAIAAAREKGVVVVLASGRPLNGMKPQLEELGMTT 64

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y+++ N + V  +    +    +     +     +     +  + +  ++  +    
Sbjct: 65  ENDYVLSYNASLVQKVKNEEVIRSQIITGADAKAIAKLAQELGVNVHAFSQEKGLITPAL 124

Query: 118 PEEMRFFKE-AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                   +       + +   L  +         D  E L    + +      +  +  
Sbjct: 125 SHYTEHESKITGMPITVIDFEELADDEQILKAMMIDEPELLSAAIKQLPEALYKQFTIVQ 184

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE +    +KG  +EA+A+ LG +  + I  GD  ND  M+  AG G  M +A  
Sbjct: 185 SAPFFLEFLNPNSNKGVGVEALAEHLGITADEVICMGDAGNDWHMIKYAGLGVAMANATD 244

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +K++   + V  +N +  V   + +  L+
Sbjct: 245 DVKEIANHITV--SNNEHGVAKVIEEFVLN 272


>UniRef50_C7JF38 Hydrolase n=8 Tax=Acetobacter pasteurianus RepID=C7JF38_ACEP3
          Length = 295

 Score =  237 bits (605), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 58/265 (21%), Positives = 111/265 (41%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++V SD+DGTLL+P+  ++ ++   ++ L   G+     + R    +    D L + + 
Sbjct: 19  IRLVVSDMDGTLLTPEKQVTRHSIAAIQTLKQAGVPVCLVSSRPPGGMEMYFDVLGLHTP 78

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
               NG  + + D  +    +LD +   +   ++  + DI   ++R  EW +       +
Sbjct: 79  YGALNGGTIFNADRTIRSRLSLDPEAVQETLDMLKVH-DIDAWLFRGHEWLVTNATGAYV 137

Query: 122 RFFKEAVFQYALYEPGLLE-PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
               +AV       P   +  + V KV  +   +E L+  E  I      R +V+ S   
Sbjct: 138 EPEAKAVRMTPTAVPSFDDYRQDVGKVTGSSADYEALMRQELEIGQLLEGRASVARSCQC 197

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L++     +KG+AL  +A     S+++    GD  ND  MLS+ G    MG +   + +
Sbjct: 198 FLDITPKDANKGYALRQLASFYNISIEEVACIGDMNNDVPMLSIGGLSIAMGQSKPEVAE 257

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 V   N++D     + +  L
Sbjct: 258 TA--HFVTAPNSEDGWAKAMEQFVL 280


>UniRef50_C6CYC3 Cof-like hydrolase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CYC3_PAESJ
          Length = 265

 Score =  236 bits (604), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 71/266 (26%), Positives = 113/266 (42%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y ++A D+DGTLL+ DH L+   +E ++    RG + V  TGR    V  + + L +   
Sbjct: 5   YDLIALDVDGTLLTDDHQLTSKTREAVREAADRGASIVLCTGRAPFSVFPVLEELGLTGT 64

Query: 62  MITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NG    D D   +I  + +              N  +  +V    E  +    PE 
Sbjct: 65  IITHNGGATIDSDTRRIIHEYGIAPQQLEPFVDYCRKN-QVHYDVNTAFEMMVESLTPEV 123

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
              + +     ++   G   PEG+ K F    S E +  +++    +W   ++   S   
Sbjct: 124 SDMYSKFHASPSVLGQGASLPEGLVK-FTVFGSKEVMDRVQEEW-EKWPPSLHTIRSGDF 181

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            ++V     SKG AL   A   G      +A G+  ND  ML  AG G  MG++   +KD
Sbjct: 182 FIDVHHPEASKGRALRQFASSRGIDRSRILAIGNYYNDISMLEFAGCGIAMGNSPDGVKD 241

Query: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266
                 V  +NA+D V + LR+   S
Sbjct: 242 AAD--VVGRSNAEDGVAYALREFAWS 265


>UniRef50_A4HGI8 Haloacid dehalogenase-like hydrolase-like protein n=6
           Tax=Trypanosomatidae RepID=A4HGI8_LEIBR
          Length = 302

 Score =  236 bits (604), Expect = 5e-61,   Method: Composition-based stats.
 Identities = 86/278 (30%), Positives = 135/278 (48%), Gaps = 16/278 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
            + V  DLDGTL +  H +S      ++ L  RG+ F+ ATGR   DV        +   
Sbjct: 6   IKAVFVDLDGTLFNSHHFISLRTATVIQALKERGVAFIVATGRPFPDVFGNLAKANLSPD 65

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGV------------VNDNPDIITNVYRD 108
           ++ITSNGAR+HD   N +FA +++ +    LF +                  I+ N+   
Sbjct: 66  FIITSNGARIHDARQNTLFAGDINTESVCRLFQLSPHLTDEGVVDPAVQARHILFNINCR 125

Query: 109 DEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGV--SKVFFTCDSHEQLLPLEQAINA 166
           D WF N    E    F  + F Y   +P     E +  +   +   +H  L+ +++ ++ 
Sbjct: 126 DRWFTNECVAEVRAAFHPS-FIYEQVDPMTQTTETLKGTHSMWIRGAHADLVCVKKYVDR 184

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
                V  +F+    L+  A G++KG A+  V   +G +L + IAFGDGMND +ML  AG
Sbjct: 185 ELSHEVTCTFALPHILDCFAKGINKGVAMRTVCTHIGIALSETIAFGDGMNDIQMLVEAG 244

Query: 227 KGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           KG +MG+A + +K   PEL VI +N ++ V   L +L 
Sbjct: 245 KGFVMGNAAEMVKQAAPELPVIPSNNEEGVAWQLEELL 282


>UniRef50_Q03T33 Predicted hydrolase of the HAD superfamily n=9 Tax=Lactobacillaceae
           RepID=Q03T33_LACBA
          Length = 271

 Score =  236 bits (604), Expect = 5e-61,   Method: Composition-based stats.
 Identities = 68/271 (25%), Positives = 115/271 (42%), Gaps = 10/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            +++A D+DGTLL+  + L+    + ++   A+GI  V  TGR    V    D ++I   
Sbjct: 3   IKLIAIDIDGTLLNEKNELAQATIDAVQAAKAQGIKVVLCTGRPLTGVQPYLDAMDIDGD 62

Query: 61  --YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             Y IT NG+    + G ++  H+L  +   DL             +   D  +      
Sbjct: 63  DQYAITFNGSVAQTISGKVLTNHSLTYEDYIDLEAWARK-VRAHFQIETPDYIYTANKDI 121

Query: 119 EEMRFFKEAVFQYALYEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                 +  + +  +    + E      +SK  F  D  + +  ++  +   + DR +V 
Sbjct: 122 SAYTIAESYLVRMLIQYREVSETPRDLTISKAMFV-DYPQVIEQVKANMPQDFKDRFSVV 180

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    +EVM    SKG  L  +  +LG +  D +  GD  ND  M+  AG G  MG+A 
Sbjct: 181 QSAPYFIEVMNRRASKGGTLSELVDQLGLTADDVMTLGDQGNDLTMIKYAGLGVAMGNAI 240

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K+      V  TNA++ V   +RK  L+
Sbjct: 241 DEVKEAAQA--VTLTNAENGVAAAIRKYALN 269


>UniRef50_Q4KBY5 Cof-like hydrolase family protein n=8 Tax=Pseudomonas
           RepID=Q4KBY5_PSEF5
          Length = 270

 Score =  236 bits (604), Expect = 5e-61,   Method: Composition-based stats.
 Identities = 73/260 (28%), Positives = 113/260 (43%), Gaps = 3/260 (1%)

Query: 7   SDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSN 66
           SD+DGTLL PDH+LSP   + ++ L   G+ F  ATGR    + Q  + L +       N
Sbjct: 11  SDMDGTLLRPDHSLSPRTLDAVRALREAGVAFSLATGRPPRAMLQQIEALGVDLPTAGFN 70

Query: 67  GARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKE 126
           G  +   DG+ +  H++  + A     +    P + T V+ D+EW +       M   ++
Sbjct: 71  GGSIVKPDGSFLARHHVPVEAAVTALLLFEPCPQVETWVFADNEWLLRNLDGALMPLERQ 130

Query: 127 AVFQYALYEPGLLEPEG-VSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVM 185
           A+           E    + K+      H  L+ LE  + A    +   S S    L++ 
Sbjct: 131 ALGYAPKVVDSFEEYLPRIDKIVAASSDHRLLVQLEARLQAATAGQAQASRSQPRFLDLT 190

Query: 186 AGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPEL 245
           A    KG AL  +A+ LG  L+   A GDG ND  M   AG    MG A +R+K      
Sbjct: 191 ALQADKGQALVTLAEYLGVPLERTAALGDGGNDPAMFQRAGLSIAMGQAEERVKRQAD-- 248

Query: 246 EVIGTNADDAVPHYLRKLYL 265
            + G+N +D     + +  L
Sbjct: 249 VITGSNLEDGAAEAIERYIL 268


>UniRef50_B2A708 Cof-like hydrolase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF
           RepID=B2A708_NATTJ
          Length = 278

 Score =  236 bits (604), Expect = 5e-61,   Method: Composition-based stats.
 Identities = 61/273 (22%), Positives = 115/273 (42%), Gaps = 12/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ VA D+D TL++ +  ++   KE++K     G+    ATGR           L +  
Sbjct: 1   MYRFVAIDIDDTLINNELDITEANKESIKAAINHGVLVTLATGRMFKSALPYAKELGLDL 60

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +IT +GA +   + G +++   +  +    +  +  +  ++  N+Y DDE  +      
Sbjct: 61  PLITYHGALIKTAVKGEVLYHKPVPLETTLQVVRLAKEK-ELHLNLYIDDELIVEEENKY 119

Query: 120 EMRFFKEAVFQYALYEPGLLE------PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
              + K  +   +L   G LE      P  +        S + +  L    N  +G  + 
Sbjct: 120 TDYYTK--IAGVSLNPVGDLENYLKQYPHKIPTKLTVVASEQMVKRLNYEFNQFFGQDLL 177

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V+ S    LE+     +KG A+  +A+         +A GD +ND  M+  AG G  + +
Sbjct: 178 VTESKSDFLELTHPEANKGDAVAKLAEIYNIPQSKTMAIGDSLNDISMIKTAGMGVAVEN 237

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A  ++KD+     ++  N +  V   + +  LS
Sbjct: 238 ARSKVKDVAD--TIVSANDESGVSEAIERFVLS 268


>UniRef50_C9XLD9 Putative hydrolase n=7 Tax=Clostridium difficile RepID=C9XLD9_CLODC
          Length = 273

 Score =  236 bits (603), Expect = 7e-61,   Method: Composition-based stats.
 Identities = 60/273 (21%), Positives = 115/273 (42%), Gaps = 10/273 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGT+L+    ++P   E+++     G   V  TGR    V ++ + L +  
Sbjct: 1   MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGRPLPGVKELLNQLNLTD 60

Query: 61  ---YMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I  NGA + ++    +I    +  D    ++  V        ++           
Sbjct: 61  EGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKKYKTKIHINTMTNLITPNE 120

Query: 117 RPEEMRFFKEAVFQYA---LYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            P +    +  +       + +  + E   + K+    D  E+L  + Q +     ++  
Sbjct: 121 APGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIV-DEPERLEEIIQQLPKNLFNKYT 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +  S    LE +    +KG AL+ +   L   +++ IA GD  ND  M+  AG G  MG+
Sbjct: 180 IVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAVGDEENDQHMIKYAGLGVAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A   +K++     V  TN ++ V   + K  L+
Sbjct: 240 ARNSIKEIAD--YVTDTNNENGVAKVINKYILN 270


>UniRef50_C4RHE6 HAD-superfamily hydrolase, subfamily IIB n=2 Tax=Micromonospora
           RepID=C4RHE6_9ACTO
          Length = 271

 Score =  236 bits (602), Expect = 7e-61,   Method: Composition-based stats.
 Identities = 74/264 (28%), Positives = 120/264 (45%), Gaps = 4/264 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VA+D+DGTLL+ + TLSP  ++ L  ++ARG   V  TGR    +  +   L      
Sbjct: 7   RLVATDIDGTLLTDERTLSPRTRDALARMSARGTPVVLVTGRPIRWLQLVYQQLAEPLPA 66

Query: 63  ITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVN-DNPDIITNVYRDDEWFMNRHRPEE 120
           I +NGA V+D     ++ A  L   + +++   +  + P +   V   D   M       
Sbjct: 67  ICANGAVVYDPVTDEVLRADPLAPKLLAEVARRLRAEVPGVSFAVEIVDSREMRHETDYP 126

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           +R+  +A    A+  P  L      K+       +  + LE    A  G       S   
Sbjct: 127 LRWDADAEAIRAITSPEELHSVPAVKLLARAGEQDPDVFLEVVAGALRGLAEATHSSYTG 186

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            +E+ A GV+K   L     +LG   +D +AFGD  ND  ML+ AG+G  + +AH  +  
Sbjct: 187 LVEISAAGVTKAAGLAWYCARLGIDERDVLAFGDMPNDVPMLTWAGRGVAVANAHPAVLA 246

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
           +    EV   N++D V  YL K++
Sbjct: 247 IAD--EVTAANSEDGVAAYLEKVF 268


>UniRef50_C2LH85 HAD superfamily hydrolase n=3 Tax=Enterobacteriaceae
           RepID=C2LH85_PROMI
          Length = 272

 Score =  236 bits (602), Expect = 8e-61,   Method: Composition-based stats.
 Identities = 57/269 (21%), Positives = 117/269 (43%), Gaps = 9/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            +++  DLDGTLL+  H ++P   + ++     G++ V A+GR    +      L + + 
Sbjct: 7   IKLIVIDLDGTLLNEQHEITPEVHQAIQHAKNSGVHIVLASGRSFNGISPYLKALNLDTS 66

Query: 61  --YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             + I++NG+++H   +G +I    L+ +     F  ++    +  +V  D++ +     
Sbjct: 67  DNFCISNNGSQIHQAENGEIITEDLLNFEDYL-YFEDLSREIGVHFHVLSDNKIYTTNRH 125

Query: 118 PEEMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                  +  +    LY   L E   +     F    +   L    Q + A    + ++ 
Sbjct: 126 ISHFTCREAFLTWTPLYYRPLSEMQRDMRFSKFMIVGTPTVLDNAMQYLPANIYQQYSIL 185

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    +E++   V+KG+A++ +A+ L  + +  +  GD  ND  ML  AG G  MG+A 
Sbjct: 186 RSAPYFIEILNTDVNKGNAVQKIAEHLKITPEKIMCIGDQDNDLAMLQYAGLGVAMGNAP 245

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           + +K +     +  +N +  V   + K  
Sbjct: 246 EEIKKVAK--FITLSNKEHGVAVAINKFI 272


>UniRef50_Q1WS49 Hydrolase, HAD superfamily n=2 Tax=Lactobacillus salivarius
           RepID=Q1WS49_LACS1
          Length = 277

 Score =  236 bits (602), Expect = 8e-61,   Method: Composition-based stats.
 Identities = 67/275 (24%), Positives = 121/275 (44%), Gaps = 10/275 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY++VA D+D TLL+ D  +SP     LK     G+  V  TGR ++ V +    L I  
Sbjct: 1   MYKLVAIDMDETLLNDDAEISPKNVSVLKKAIKDGVKVVLNTGRSYLSVQENLKTLGIYQ 60

Query: 59  --KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGV-VNDNPDIITNVYRDDEWFMN 114
               Y+++ NG  +  + D  ++    L  DI   LF + +   P+   +VY  DE +M 
Sbjct: 61  TKDQYVVSFNGGAIVENKDLKVVHVEGLTFDIVKQLFDISLRYYPESCIHVYTLDELYMW 120

Query: 115 RHRPEEMRFFKEAVFQYALYEP---GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
               +E  + +    ++   +      LE   ++K+    +  ++ L   +      GD+
Sbjct: 121 NVNQDEKDYLQPRGVEWTELQEPNIDFLEDTPITKIIINVNDMDKRLAFNEIARKEIGDK 180

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
              ++S+   +E       KG  +  +A+ LG   ++ IA GD  ND  M+  AG G  +
Sbjct: 181 FKTTYSSGRYIEFNNISTDKGTGMLKLAEMLGIKPEETIAIGDNSNDLPMIEAAGVGVAV 240

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +A++++      +     N  DAV   + K   +
Sbjct: 241 RNANEQVLSKADYIC-KRDNNHDAVAEAVDKFVYN 274


>UniRef50_UPI000196CFC2 hypothetical protein CATMIT_02842 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196CFC2
          Length = 262

 Score =  236 bits (602), Expect = 9e-61,   Method: Composition-based stats.
 Identities = 72/270 (26%), Positives = 129/270 (47%), Gaps = 14/270 (5%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQ + SD+DGTLL+ DH +SP  ++ +K L    I F+  + R    +  I    +I  
Sbjct: 1   MYQCILSDIDGTLLTDDHHMSPKTRDAIKSL---DIPFLPVSARSPEGIYPILKENDIVC 57

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFMNRHRPE 119
            MI  +G  + D  GN+++ + ++     ++   + +   D   N+Y   +W +     E
Sbjct: 58  PMICFSGGLILDEKGNVLYENGMNYKQTEEVITFIKEKKFDCTINIYSLHDWLVE--DKE 115

Query: 120 EMRFFKEAVFQYALYEPGLLEPEG----VSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           + R  +E     A  + G L        + K+   C+       +E+++  R+    +++
Sbjct: 116 DPRVLREERIVKAEAQKGTLSSLDSSRKIHKLLCMCNPL-YTKEIEKSLKERFP-HCSIA 173

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S+   +E+M  GV+K  A+  +        KD +AFGD  ND EML   G G  MG+A 
Sbjct: 174 CSSDILIEIMNEGVTKADAINHLCDYYSIDKKDIVAFGDNYNDKEMLESVGMGIAMGNAP 233

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +K++    +V  TN  D + + L+KL++
Sbjct: 234 DDIKNIA--RDVTSTNNQDGIFNALQKLHI 261


>UniRef50_P94592 Uncharacterized phosphatase ywpJ n=7 Tax=Bacillaceae
           RepID=YWPJ_BACSU
          Length = 285

 Score =  235 bits (601), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 76/289 (26%), Positives = 128/289 (44%), Gaps = 32/289 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLL+  H +S   +  L+     GI  V +TGR H DV  I + L IK+++
Sbjct: 2   KLIAIDLDGTLLNSKHQVSLENENALRQAQRDGIEVVVSTGRAHFDVMSIFEPLGIKTWV 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I++NGA +HD +G L     +D+  A D+   + ++ +    V+     +  ++  E + 
Sbjct: 62  ISANGAVIHDPEGRLYHHETIDKKRAYDILSWL-ESENYYYEVFTGSAIYTPQNGRELLD 120

Query: 123 F------------------------FKEAVFQYALYEPGLL---EPEGVSKVFFTCDSHE 155
                                    + ++ F Y      L    EP     +       E
Sbjct: 121 VELDRFRSANPEADLSVLKQAAEVQYSQSGFAYINSFQELFEADEPIDFYNILGFSFFKE 180

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           +L    +       + + +  S     E+ +   SKG AL+ +AK+L   L++  A GD 
Sbjct: 181 KLEAGWKRYE--HAEDLTLVSSAEHNFELSSRKASKGQALKRLAKQLNIPLEETAAVGDS 238

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +ND  ML  AGKG  MG+A + +K +     V  TN +  V H ++ L 
Sbjct: 239 LNDKSMLEAAGKGVAMGNAREDIKSIADA--VTLTNDEHGVAHMMKHLL 285


>UniRef50_C9KQH1 HAD phosphatase family protein n=2 Tax=Clostridia
           RepID=C9KQH1_9FIRM
          Length = 274

 Score =  235 bits (601), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 71/272 (26%), Positives = 124/272 (45%), Gaps = 10/272 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A DLDGTL + +  ++   +E L  +   G+  V A+GR    + +    L++K 
Sbjct: 1   MYKMIALDLDGTLNNDEKKITEKTREALLSVQQHGVTVVLASGRQAPGLAREAQALDLKD 60

Query: 61  Y---MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN-- 114
           Y   +++ NG R+ D   G ++F   +DR  A      +   P++   V   +  F    
Sbjct: 61  YHGLLLSYNGGRIQDATTGEVLFDQAIDRATALRFLRHLEAYPELSPIVDDGESIFTTDA 120

Query: 115 -RHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKV-FFTCDSHEQLLPLEQAINARWGDRV 172
            RH+ ++         +        +E  G + V   T   +E L+P  + I   + D +
Sbjct: 121 RRHKVQDESRNNNLKVEIVANIADAVEARGFAPVKILTAAPNEILVPRLEDIRRGFEDEL 180

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           +   S     E    GVSK  +L  V ++ G +  + +AFGD  ND  ML  AG G  MG
Sbjct: 181 SFVQSAPWFYEATVKGVSKSTSLAIVCERFGIARAEVMAFGDAQNDMSMLDFAGHGVAMG 240

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A   LK++    E+  +N +D +   L + +
Sbjct: 241 NACPELKEMAD--EITLSNNEDGIAASLTRHF 270


>UniRef50_C2D902 HAD family hydrolase n=1 Tax=Atopobium vaginae DSM 15829
           RepID=C2D902_9ACTN
          Length = 292

 Score =  235 bits (601), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 68/275 (24%), Positives = 115/275 (41%), Gaps = 11/275 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++VA DLD TLL+    +    +  ++   A+G+  V ++GR    +  I D +  K 
Sbjct: 19  MYKLVAVDLDETLLNDARHVPLRVRRAIEQARAKGVYIVPSSGRSFAIMQYILDEIGAKD 78

Query: 61  ----YMITSNGARVHDLDGNLI--FAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN 114
               Y I+ NGA + +   N I         D  + ++       ++  +VY     +  
Sbjct: 79  MKDEYAISCNGACITENAHNTIIDLQPPTPWDFCNKIWKHGIQLGNVGVHVYTLASIYTT 138

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
           + R ++   F              LE      + K+ +  +    L  L   +     D 
Sbjct: 139 KWRDDDRNIFTLTGIPAIETREANLEFLRNTHIVKILYMNNDFAYLQQLAHDMRDLTRD- 197

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           V V+FS+   +E    G+SKG AL+ +A  LG  + + IA GD  ND+EM+  AG G  M
Sbjct: 198 VGVTFSSNCYMEFTPKGISKGAALKRLAHHLGIDMSETIAVGDSANDSEMIKAAGLGVCM 257

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +A   +K     +     N +  V   + K  L+
Sbjct: 258 ANADDSMKAQADYVTQ-NNNNEGGVAEVIEKFILN 291


>UniRef50_Q7N6X1 Similar to unknown protein n=2 Tax=Photorhabdus RepID=Q7N6X1_PHOLL
          Length = 275

 Score =  235 bits (600), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 100/264 (37%), Positives = 145/264 (54%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY ++A+DLDGTLL  +  +  + ++ L  L++ G   VFATGRHH DV  I  + +I  
Sbjct: 9   MYNLIATDLDGTLLLQEDIIGKFTRKVLTDLSSMGKQIVFATGRHHADVNSIIGDFDIPV 68

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++ITSNGAR+     NL    +L   I   +      + D++ N+Y   +W  N      
Sbjct: 69  HLITSNGARLTSACKNLDIRQHLPSHIVKRVIEETQVDNDLVINMYCGSQWLTNEVNHNF 128

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDS--HEQLLPLEQAINARWGDRVNVSFST 178
             F +   F         +  + V KVFF   S  H+ L+ LE+ +   + D V+++FS 
Sbjct: 129 SDFSQNDNFNPTFKCVDEMPCDAVEKVFFIHKSRNHDALVKLERHLIDLFSDNVSIAFSF 188

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LEVM  GVSKG AL  +A  LG  +   IAFGDGMND EMLS   KG IMG+AH R+
Sbjct: 189 PWSLEVMGSGVSKGQALIQLAGFLGIPMNKTIAFGDGMNDVEMLSTVAKGVIMGTAHNRV 248

Query: 239 KDLHPELEVIGTNADDAVPHYLRK 262
           K   P+ ++IG+  +++V HYL +
Sbjct: 249 KQALPDADIIGSCCEESVAHYLSE 272


>UniRef50_C5RPZ1 Cof-like hydrolase n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RPZ1_CLOCL
          Length = 277

 Score =  234 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 71/275 (25%), Positives = 119/275 (43%), Gaps = 17/275 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++V  D+DGTLLS  H + P   E +K  T  G+    ATGR         + L IK+ 
Sbjct: 3   IKLVCIDMDGTLLSNHHEVHPKNLEAIKKATDLGVKIAIATGRIFASAKIYCELLGIKTP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I++NG  +   D  ++  HN+  +    +  V+     +   +Y  D    N + PE  
Sbjct: 63  IISANGGYIRYGDT-VMAEHNMGYENCKKIVEVLEKFKSVYY-LYTADSMITNANIPETH 120

Query: 122 RF----------FKEAVFQYALYEPGLLEP-EGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            +           K   + Y      +    + + K     +  E++  + Q IN   G 
Sbjct: 121 PYRSMNDQLSDKDKLKFYHYDDISDAVENHGDKIIKCIVMEEDFEEIQKIRQDINKIQG- 179

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + V  S    +E+MA GV+KG   EA+AK  G+S  + +  GD  ND  M++ AG G  
Sbjct: 180 -LEVVSSYTNNIEMMAAGVTKGKGAEALAKYYGFSRDEVMCIGDSENDLSMVTYAGFGVA 238

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           MG+ ++ +K       +  TN +  V   + K  +
Sbjct: 239 MGNGNEAVKKAAK--YITDTNVEGGVGKAIEKFVI 271


>UniRef50_Q4DMD3 Haloacid dehalogenase hydrolase, putative n=2 Tax=Trypanosoma cruzi
           RepID=Q4DMD3_TRYCR
          Length = 326

 Score =  234 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 105/292 (35%), Positives = 156/292 (53%), Gaps = 32/292 (10%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL------- 56
           VVA+D+DGT+L P H L+   K+TL  L+ RG++ +FATGRHH  V   R +L       
Sbjct: 31  VVATDMDGTILDPKHRLTERTKDTLYELSTRGVHIIFATGRHHSCVYATRRDLLEHYRRR 90

Query: 57  ----EIKS---------YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGV--VNDNPD- 100
                +           Y+I+SNGARVH+ +G+LIF  +LD DI   L+    + D+ D 
Sbjct: 91  STARGVPDSPTTGYEGFYIISSNGARVHNPNGDLIFLRDLDSDIVRVLYERFGIRDHGDD 150

Query: 101 ----IITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEP---EGVSKVFFTCDS 153
               +  + Y+ ++W++NR    +            L+ P LL+     GV KV F C  
Sbjct: 151 PRKVLSVSAYQTEKWWINRTIMSDEESLAMFGVVPDLH-PDLLKEFPTTGVGKVCFRCYD 209

Query: 154 HEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLK-DCIAF 212
            + L   E  I   +  R     S+  CL+VMA GVSK  AL  + + L +  + + IAF
Sbjct: 210 RDILHQYEAEIKELFHGRATAVMSSEICLDVMAAGVSKAAALREIGRILKFDPEREAIAF 269

Query: 213 GDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           GD MND +ML    KGCIMG+   RLK+  P LEV+G++++D V   L++++
Sbjct: 270 GDSMNDGDMLCSVAKGCIMGNGQSRLKESLPHLEVVGSSSEDGVARKLQEVF 321


>UniRef50_C0Z8L2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z8L2_BREBN
          Length = 279

 Score =  234 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 67/280 (23%), Positives = 121/280 (43%), Gaps = 19/280 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+DGT+L  +HTLS   +  +  L  +G++   ATGR +     +     I + 
Sbjct: 3   YKLLALDVDGTILMSNHTLSKVTERAITQLVQQGVHVTLATGRAYPSAKSLAQQFRISAP 62

Query: 62  MITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH---- 116
           +++ +GA V D     +++   +  +IA+ +  ++  +  +   +  +     NR     
Sbjct: 63  LVSHDGAYVADPKTDQVLYVQRIPHEIAARITDILVSH-GLDVMLLHEAYAVTNRTWKLT 121

Query: 117 ------RPEEMRFFKEAVFQYALYEPGLL-----EPEGVSKVFFTCDSHEQLLPLEQAIN 165
                     +R   +  +   +    L+     + E  +   F     ++LL   Q + 
Sbjct: 122 DLFPLLNAWTLRQLWKNQYPLKIQASRLIAGYVRKHEVCAPKIFVTGDEKRLLEARQELE 181

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
                 + V+ S    LE++  G+SK   L  V+++L     + +A GD  NDAEML  A
Sbjct: 182 KAELSGIRVTASGANNLEILPVGISKASGLAVVSERLAIQPDEIVAVGDNYNDAEMLQFA 241

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G G  MG+A   LK L     V  TN    V   + K +L
Sbjct: 242 GMGVAMGNAPDDLKQLARH--VTETNDRHGVAEVIEKFFL 279


>UniRef50_P44447 Uncharacterized protein HI0003 n=16 Tax=Haemophilus influenzae
           RepID=Y003_HAEIN
          Length = 262

 Score =  234 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 64/264 (24%), Positives = 121/264 (45%), Gaps = 5/264 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V SD +GTLL+  HT+SP     +K LTA GI FV  + R  + +      LE  +
Sbjct: 2   MYKAVFSDFNGTLLTSQHTISPRTVVVIKRLTANGIPFVPISARSPLGILPYWKQLETNN 61

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            ++  +GA + + +   I++  ++     ++  V+ ++P +  N Y +++    R    +
Sbjct: 62  VLVAFSGALILNQNLEPIYSVQIEPKDILEINTVLAEHPLLGVNYYTNNDCHA-RDVENK 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
              ++ +V +  ++    +      K+    ++ E +      +  ++   +++  S   
Sbjct: 121 WVIYERSVTKIEIHPFDEVATRSPHKIQIIGEAEEIIEIEV-LLKEKFP-HLSICRSHAN 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LEVM    +KG A+  +    G    + IAFGD  ND +ML   G G  MG+A   +K 
Sbjct: 179 FLEVMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHVGLGVAMGNAPNEIKQ 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                 V  TN +D +   L + +
Sbjct: 239 AAN--VVTATNNEDGLALILEEKF 260


>UniRef50_C9LXL5 HAD-superfamily hydrolase, family protein IIB n=1 Tax=Selenomonas
           sputigena ATCC 35185 RepID=C9LXL5_9FIRM
          Length = 268

 Score =  234 bits (598), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 63/266 (23%), Positives = 113/266 (42%), Gaps = 5/266 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++ +D+DGTLL   + +S   +  LK   A+G++   ATGR H+        + +   
Sbjct: 3   IRMIVTDMDGTLLDAKNGISEKNRAALKEAAAKGVHVAIATGRMHLSALPYAKEIGVTVP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +++ NGA V    G  +FA  +  D+  ++   + ++       Y D+  F         
Sbjct: 63  IVSCNGALVKTTAGEELFASPIAPDVVREILDCMKEH-GWYVQPYTDEGLFFCERDCRAC 121

Query: 122 RFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            + K A  +      +  L     V K+    D  E+       I+  +  +V    S  
Sbjct: 122 AYEKLAGIEGKAVGWDGLLALGTRVFKLLSISDRAEETAVRAAEISRMFEGKVRAVRSKE 181

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +++MA GVSK  ++E +A  LG ++ + +A GD  ND EML+ AG G  M +     +
Sbjct: 182 KYVDIMAEGVSKAASIERLAASLGINMSEVLALGDSDNDCEMLAAAGIGVAMATGTPAAR 241

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
           +      +    A D V   +    L
Sbjct: 242 EAAD--FLAENGAADGVARAVHAYVL 265


>UniRef50_UPI0001BC341D haloacid dehalogenase-like hydrolase n=1 Tax=Butyrivibrio crossotus
           DSM 2876 RepID=UPI0001BC341D
          Length = 269

 Score =  234 bits (598), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 62/270 (22%), Positives = 116/270 (42%), Gaps = 10/270 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++A D+DGTL +    ++   K  +     +G   + A+GR    +    + L +K  
Sbjct: 3   YKILAFDIDGTLTNSQKIITEETKRAIFAAMDKGCKVLIASGRPVKGLRGYAEELHLKEN 62

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NG  +    D  +++   + +    +++ +   +  +    Y+ +        
Sbjct: 63  GGYILSLNGGYIMSCADEKVLYDVKVPKKYYKEIYELSKKH-GVNLLTYQGETVISEDID 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEG--VSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
            E +                L E     V+K   T D  + L  +E+ +  +  + ++V 
Sbjct: 122 DEYLDIEARLNGLPKKKVDNLYEYLDFEVNKFLMTGDG-DYLAEVEKDVYDKLHNNLDVY 180

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE++   V+KG ALEA+   LG    + +AFGDG ND  M+  AG G  MG+A 
Sbjct: 181 RSEPFFLEILPKDVNKGKALEALLAILGVDRDELMAFGDGYNDKTMVEYAGLGVAMGNAK 240

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +K+      V  TN +D +   + K  L
Sbjct: 241 DVVKEAAD--YVAPTNDEDGIVEVIHKFIL 268


>UniRef50_Q384S8 Haloacid dehalogenase hydrolase, putative n=3 Tax=cellular
           organisms RepID=Q384S8_9TRYP
          Length = 312

 Score =  234 bits (598), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 82/289 (28%), Positives = 135/289 (46%), Gaps = 27/289 (9%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI----- 58
            V  DLDGT+L  +H +S   K TL  + + G++ + ATGR    V  I   L       
Sbjct: 22  AVVVDLDGTILDDNHRVSDVTKATLYEVASCGVHIIIATGRPREGVAAIEQELNSYFRCN 81

Query: 59  --------------KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVND------- 97
                           +++ SNGAR+++  G LI A ++D  +   ++  V +       
Sbjct: 82  SRVPGRATSLAEVKGFHLVASNGARIYNTTGELISAESIDNSVVRAIYERVTESNINANS 141

Query: 98  NPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQL 157
              ++ +V++   W++N   PEE    K                +GV K+     +   L
Sbjct: 142 EDSMLVSVHQTGAWWVNNVLPEEWLRRKYGTLPEVRQNLSDFPTDGVGKICLRSFNEGTL 201

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLK-DCIAFGDGM 216
              ++ ++ ++   +    ++  CL++M  GVSK  AL  V + L +    D IAFGD +
Sbjct: 202 RTFQKELDTKYEHYITTVMTSDHCLDIMPKGVSKASALRMVGEILNFEPHRDAIAFGDSL 261

Query: 217 NDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           ND +ML    KGCIM +    LK+L P +EV+G N +D V H LR+++L
Sbjct: 262 NDRDMLESVAKGCIMKNGKNELKELLPHVEVVGCNEEDGVAHKLREVFL 310


>UniRef50_B1BZI7 Putative uncharacterized protein n=2 Tax=Clostridium spiroforme DSM
           1552 RepID=B1BZI7_9FIRM
          Length = 268

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 73/270 (27%), Positives = 121/270 (44%), Gaps = 11/270 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQVV SD+DGTLL+  H ++P     +K +  +GI FV  + R    +  I     +  
Sbjct: 1   MYQVVFSDVDGTLLNDQHCITPLTLLAIKKIQQQGIPFVIVSARSPSGIYPILKENNLVC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVN-DNPDIITNVYRDDEWFMNRHRPE 119
            MI   G  + + +  +I+   ++  +A  +   +  +N DI   +Y  D+W +      
Sbjct: 61  PMICYGGGMILNHENEIIYEKGMETSLALKIINYIEANNFDIAWCIYSFDDWLVKDCL-- 118

Query: 120 EMRFFKEAVFQYALYEPG----LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           + R  KE     A    G    + +   V K+   C +HE +  LE  +   + +   + 
Sbjct: 119 DPRIIKEEQIVRAKSRQGNQIEIKKLSKVHKILCIC-NHEHINDLETKLKIMFKE-CQIV 176

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S+   +E+    +SK  A++     L  ++K+ IAFGD  ND EML + G G  M +A 
Sbjct: 177 KSSNILIEITHQNISKAFAIKKYCDLLNINIKNTIAFGDQYNDLEMLKIVGCGIAMKNAP 236

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +K      +V   N  D +   L KL L
Sbjct: 237 LGIKKEVK--QVTKDNNHDGIYFALSKLNL 264


>UniRef50_A6LQL6 Cof-like hydrolase n=1 Tax=Clostridium beijerinckii NCIMB 8052
           RepID=A6LQL6_CLOB8
          Length = 270

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 70/272 (25%), Positives = 127/272 (46%), Gaps = 14/272 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKL-LTARGINFVFATGRHHVDVGQIRDNLEIKS 60
            ++V  D+DGTLL+ +H ++   K T+      + I  +  + R    +  +++ L I+ 
Sbjct: 4   IRMVCLDIDGTLLNSNHEVTEKVKSTINKVANNKKIPVILVSARMPKGIRFLQEELGIEE 63

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR----- 115
            +I  +GA + D D +++    +D      ++ + ++N +I  ++Y+DDEW++ +     
Sbjct: 64  PIICYSGALILDKDNSVLAREAIDVSNFEKIYKLTSEN-NIHMSLYKDDEWYIEKLDYWA 122

Query: 116 -HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
               E        +    L E    E  G SK+    +  E +  L++ I   + + +N+
Sbjct: 123 KQESEITNIIPNIIDFNKLIEQWKREGVGPSKILCMSNPKE-INFLKENI---YDNDLNI 178

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S  T LE+M    SK  A+  + KK      + IA GD  ND +ML  AG G  MG+A
Sbjct: 179 YPSKPTYLEIMPIKASKTSAITCLQKKFSIDKSEIIAMGDNYNDIDMLEYAGVGVAMGNA 238

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            + +K      +V  TN +D V   L K  ++
Sbjct: 239 PEDVKKHAD--DVTLTNDEDGVAEALIKYVIN 268


>UniRef50_B6XF55 Putative uncharacterized protein n=2 Tax=Providencia
           RepID=B6XF55_9ENTR
          Length = 269

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 68/269 (25%), Positives = 112/269 (41%), Gaps = 9/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            ++VA DLDGTLL+  H +SP  KE +     +G+  V A+GR +  +      L + + 
Sbjct: 3   IKLVAIDLDGTLLNSQHQISPVVKEAITRAHEQGVRIVLASGRPYSGIQPYLQELGLDTA 62

Query: 61  --YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRH 116
             Y I++NG+ +H   DG+ ++ + LD       F  +  N  +  +   D+  F  NRH
Sbjct: 63  NNYCISNNGSVIHQANDGSHLYENLLDFADY-QYFAELASNVGVHMHALADNTMFTANRH 121

Query: 117 RPEEMRFFKEAVFQYALYEP-GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                           +Y P   +E           D  E+L      I     +  ++ 
Sbjct: 122 ISRYTIHDAYITNTPLVYCPVNEMESSLSFTKIMMIDHPEKLDVGISYIPENTFENYSLI 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            ++   LE+     SKG AL+ +  KL  +    ++ GD  ND  ML  +     MG+A 
Sbjct: 182 KTSPYFLEISNKDASKGSALKVLCDKLALTPDKVMSIGDQNNDVTMLQYSSVSVAMGNAA 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             ++++     V  TN  D V   L K  
Sbjct: 242 PHIREIVK--FVTSTNDCDGVAVALNKFI 268


>UniRef50_C2BEV0 HAD superfamily hydrolase n=1 Tax=Anaerococcus lactolyticus ATCC
           51172 RepID=C2BEV0_9FIRM
          Length = 272

 Score =  234 bits (597), Expect = 3e-60,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 117/271 (43%), Gaps = 8/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTL++ +  ++   +E L   +  G   +  +GR    + +    L    
Sbjct: 1   MKKLIAVDVDGTLVNSEGVITARTREALIAASKAGHEVMIVSGRPTYGLREQAKALAFDE 60

Query: 61  Y---MITSNGARVHDLDGNLIF-AHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR- 115
           +   + + NG +++D   + I   H +D D+A ++    + + D+I  V   +  F +  
Sbjct: 61  FGGILSSYNGGQLYDFKADTILVNHPMDFDLAKEILEF-SKSLDLILMVPHGEVIFTDDA 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                 R       +           +            ++L      I  ++GDR    
Sbjct: 120 ENFYSSRESGMLKMEVRGVRDIRDSLDFAPNKLLFAQDPDKLDAPCANIREKFGDRTEQV 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S     EVM  G+SKG ++    K  G  +KD I FGD MND  M  +AG G  MG+A 
Sbjct: 180 KSARFYYEVMPMGLSKGSSIIEACKIFGIDIKDTIVFGDEMNDMSMFEVAGTGVAMGNAV 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           + +K++     V  TN +D + +YL K  L+
Sbjct: 240 EPVKNVAD--FVTKTNNEDGIAYYLEKFVLN 268


>UniRef50_D1PLJ0 Hydrolase n=1 Tax=Subdoligranulum variabile DSM 15176
           RepID=D1PLJ0_9FIRM
          Length = 308

 Score =  233 bits (596), Expect = 4e-60,   Method: Composition-based stats.
 Identities = 63/272 (23%), Positives = 119/272 (43%), Gaps = 12/272 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+V+A DLDGTL + +  ++P  K  L+    RG+  V A+GR  V +  +   LE++ +
Sbjct: 39  YKVLALDLDGTLTNSEKIITPRTKAALQEAARRGVCIVLASGRPTVGIQPLARELELEKF 98

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              +++ NG ++ D   G  +  H    D+   +        +++   Y D    +  H 
Sbjct: 99  GGCILSYNGGKIIDCKTGKTLVQHAFPPDLIEPVCTFSR-YWNVVPLTY-DAGGVVTEHA 156

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPE---GVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                  +  + +  + E   L  E    + K+  T D  + +  +E+ +   +  ++++
Sbjct: 157 DSPYVQEEARINKIPVREVPDLPAEVRYPIHKLLLTGDPAD-MPHVEELMQQEFAGKLSI 215

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    +E M   V K  +L+ + +  G + ++ +A GDG ND  M+  AG G  MG+A
Sbjct: 216 YRSQPFFIETMPLNVEKAASLDLLLRSKGLTAENLMACGDGWNDLPMIRFAGLGVAMGNA 275

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              +K           N  D V   + +  LS
Sbjct: 276 QAPVKAAADCQ--TADNDHDGVGLAVEQYILS 305


>UniRef50_B8DIC3 Hydrolase, Cof family n=18 Tax=Listeria RepID=B8DIC3_LISMH
          Length = 288

 Score =  233 bits (596), Expect = 5e-60,   Method: Composition-based stats.
 Identities = 77/288 (26%), Positives = 127/288 (44%), Gaps = 28/288 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +V+ASD+DGTLL+ D  ++    E ++   A+GI+FV  TGR + D   + +   + +
Sbjct: 1   MIKVIASDMDGTLLNSDIEIAQENVEAIEKARAKGIHFVLCTGRMYDDAMGLINKANLYA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLF----------GVVNDNPDIITNVYRDDE 110
             I  NGA + D  G +I  H +DR++A + +              D   I T+  R  E
Sbjct: 61  PAICMNGAEIRDEHGKIILQHPIDRNLARNTYNTLTELGMYTEFFTDMGPITTDKARGKE 120

Query: 111 WFMNRHR-------------PEEMRFFKEAVFQYALYEPGLLEPE-GVSKVFFTCDSHEQ 156
           + +  H+               E RF  + V +    E  L   +  + K        + 
Sbjct: 121 FMIEMHKRIHPDVSAETIMDKVEERFESKDVHEIPDVERILGNKDLTILKFISFSSDKDI 180

Query: 157 LLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGM 216
           L   +Q +       ++V+ S    +E+      KG +L+   +KLG +L +  A GD M
Sbjct: 181 LAKAKQKLEK--DSELSVTSSFSDNIEITHREAQKGISLQYYVEKLGVTLDETFAIGDNM 238

Query: 217 NDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ND  ML MAG    MG+  + +KDL     V  +N +  V   + K+ 
Sbjct: 239 NDISMLKMAGYSVAMGNGEEEVKDLAEH--VTLSNDEHGVAAAIYKML 284


>UniRef50_A0Q2R8 Cof-like hydrolase n=1 Tax=Clostridium novyi NT RepID=A0Q2R8_CLONN
          Length = 269

 Score =  233 bits (595), Expect = 5e-60,   Method: Composition-based stats.
 Identities = 65/267 (24%), Positives = 116/267 (43%), Gaps = 8/267 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY+++A D+DGTLL+ D  +S     T+     RGI     TGR +  +      + +  
Sbjct: 1   MYKLIAIDMDGTLLNSDKKVSKENIATINEAMKRGIRVAICTGRPYSGIEPYAKEIGLCK 60

Query: 59  -KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I+ NG+ V +  D   I A  L+ +  + +   + D    +  V   D    N  
Sbjct: 61  DDEYIISQNGSYVSNGNDTKTISAKYLNVEETNKILSYLEDKEIGVVLVTDKDYLAYNCE 120

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKV--FFTCDSHEQLLPLEQAINARWGDRVNV 174
             EEM+   + VF+         +     K+      D+  ++  + + ++    +   V
Sbjct: 121 INEEMKRDADLVFKTIKMFDKSKDSIENLKLVKIMIMDNSHKIDNIIENMDKNIINSCYV 180

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    +E+MA  V KG+ L  +A+ L    KD +  GD +ND  M  +AG G  M +A
Sbjct: 181 VRSMPYLIEIMAKNVDKGYGLSKLAEHLNIDHKDIMVIGDELNDIGMFKVAGLGVAMANA 240

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLR 261
           +  +K L     +  +N ++ V + + 
Sbjct: 241 NIEIKRLAD--FITLSNDENGVSYAID 265


>UniRef50_A5Z5X7 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
           ATCC 27560 RepID=A5Z5X7_9FIRM
          Length = 269

 Score =  232 bits (594), Expect = 6e-60,   Method: Composition-based stats.
 Identities = 67/269 (24%), Positives = 120/269 (44%), Gaps = 11/269 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK--- 59
           +V+  DLDGTL + D  ++P   + LK +   G     A+GR    V Q+   LE+    
Sbjct: 4   KVLFLDLDGTLTNDDKKVTPKTLKALKQIMEEGHIVALASGRPTPGVAQVAKTLELDKYG 63

Query: 60  SYMITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y+++ NG +V +     +I+ + L ++   +L      N  I    Y DD   +     
Sbjct: 64  GYVLSFNGGKVINWKTKEVIYENALSKEYIPELVDYATGNK-IGLITYDDDSIVVGTPID 122

Query: 119 EEMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
           E +   +  + +  L E  L+E      +K   T    E     E+ ++ ++  R+++  
Sbjct: 123 EYIEL-ESFINKLPLKEKNLVEYVDYNPNKCLLTAPG-EIAAEHEKILSKKFEGRISIYR 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    +E +  G+ K H++E +   LG   ++ IA GDG ND  M+  A  G  M +A  
Sbjct: 181 SEPFFIEALPMGIDKAHSIEVLINHLGIPKENTIACGDGFNDLTMIKYAHVGVAMANATD 240

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +K+      +  +N +D + H + K  L
Sbjct: 241 VVKENAD--YITKSNNEDGIAHVIEKFIL 267


>UniRef50_A3MZH9 Predicted hydrolases of the HAD superfamily n=9 Tax=Pasteurellaceae
           RepID=A3MZH9_ACTP2
          Length = 272

 Score =  232 bits (594), Expect = 7e-60,   Method: Composition-based stats.
 Identities = 71/274 (25%), Positives = 124/274 (45%), Gaps = 17/274 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           YQ +A DLDGTLL+P  T+   +K+ +K    +GI   F TGRHH  V      + + + 
Sbjct: 3   YQAIAFDLDGTLLNPHATILESSKQAIKKAREKGIKVFFVTGRHHTAVRPYYAEIGLDTP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++  NG  ++D     ++    L  + AS L         I T VY  D     +  P  
Sbjct: 63  VVCCNGTYLYDFQHDKVLSGKPLTAEQASHLINDAKSQ-GIHTAVYFRDAMTYEQLNPHF 121

Query: 121 MRF----------FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            +            +  V+Q   ++  + +   V KV  +  + E++    + +     D
Sbjct: 122 AKLQQWVASCPESVRPNVYQLESFQQEIDKGTTVWKVLISDPNLEKMQNFVKKLPL---D 178

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           + +  +S +  +++ + G SKG  L  + K  G   ++ IAFGD  ND  ML + G G  
Sbjct: 179 QFSPEWSWVDRVDITSVGNSKGAMLAELLKMEGLEPQNVIAFGDNFNDISMLELVGLGIA 238

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           MG + + +K    +   IG+N++D++   L +L 
Sbjct: 239 MGDSEEEVKQRADK--TIGSNSEDSIAKTLTELL 270


>UniRef50_C6QV31 Cof-like hydrolase n=1 Tax=Geobacillus sp. Y4.1MC1
           RepID=C6QV31_9BACI
          Length = 296

 Score =  232 bits (594), Expect = 8e-60,   Method: Composition-based stats.
 Identities = 77/286 (26%), Positives = 131/286 (45%), Gaps = 30/286 (10%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A DLDGTLL+  + +S    + +K     GI  V ATGR H DV +I  +  I++++I
Sbjct: 6   LMAIDLDGTLLNKHNEISRENIQAMKEAQKNGIEIVVATGRAHFDVQEIFKHTGIRTWII 65

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM---------- 113
            +NGA +H  DG L  +  LD+D A ++   + +  +    V+ D   F           
Sbjct: 66  GANGATIHKPDGQLFLSTPLDKDKAIEILQWL-EQEEYYYEVFSDSAIFTPQKGRELLSI 124

Query: 114 --------------NRHRPEEMRFFKEAVFQYALYEPGLLEPE-GVSKVFFTCDSHEQLL 158
                            +   ++ + ++ F +      LL+P   +  +       E+L 
Sbjct: 125 EMDRLISANPELDSEELKSAALKQYSQSGFVFISSYKELLKPSINIYNILVFSFDKEKLN 184

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
                      + + +  S     E+     SKG+AL+ +AK+LG  L   IA GD MND
Sbjct: 185 RGWNKFQD--CNDLTLVTSANYNFELEHIEASKGNALKILAKELGIPLSQTIAIGDSMND 242

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             M+S+AGKG  MG+A + +K++    EV  +N +  V + + +L 
Sbjct: 243 YSMISIAGKGIAMGNACEEIKNIAK--EVTLSNDEHGVAYVINRLL 286


>UniRef50_D1AIM0 Cof-like hydrolase n=1 Tax=Sebaldella termitidis ATCC 33386
           RepID=D1AIM0_SEBTE
          Length = 262

 Score =  232 bits (593), Expect = 9e-60,   Method: Composition-based stats.
 Identities = 73/263 (27%), Positives = 128/263 (48%), Gaps = 5/263 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           + V  DLDGT+L  D T+S    + +  L  R IN   +TGR         + L ++   
Sbjct: 4   KSVFLDLDGTVLHDDKTISKRLADVVTELKKR-INIYVSTGRSWESASSYVEKLGLEDLA 62

Query: 63  ITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           I  NGAR+ +L    +I    L+ +    L  V  ++  I  N+Y+DD+W++     E  
Sbjct: 63  INYNGARIINLKTKEVISEKPLNEETVKKLIAVSREHK-IHLNLYKDDKWYVENAGREAE 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            +      ++ L        +  +K  F  + +++L  +++ +  +    V   FS+   
Sbjct: 122 YYSNLTDIKWNLINFDDFMGKKSTKALFVAE-YKRLEEIKEILQKKLSG-VEYVFSSEYY 179

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +E++  GV+KG A++ V ++ G S  + +AFGD  ND EML     G +MG+A + LK++
Sbjct: 180 MEILQEGVNKGSAVKKVLEESGVSKDEAMAFGDHWNDKEMLQYVKYGYLMGNAPENLKEV 239

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
             + ++I  N +D V   L KL 
Sbjct: 240 FDKEKIIAANNEDGVAQILEKLI 262


>UniRef50_B7HYF7 Hydrolase, haloacid dehalogenase-like family n=81 Tax=Bacillales
           RepID=B7HYF7_BACC7
          Length = 273

 Score =  232 bits (593), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 67/253 (26%), Positives = 116/253 (45%), Gaps = 9/253 (3%)

Query: 18  HTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY---MITSNGARVHDLD 74
           HT+SP  KE L     +G+  V A+GR    +  +   L ++ Y   +++ NGA++ +  
Sbjct: 19  HTISPRTKEALMTAQEQGVKVVLASGRPTFGMRNVAKELRLEEYGSFILSFNGAKIINCK 78

Query: 75  -GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYAL 133
               IF+  L  +I  +LF  ++   D+  + Y  D+     + P              +
Sbjct: 79  TNEEIFSSTLSPEIVHNLFE-ISKTEDVWIHTYMGDDIVTEENNPYTEIEGDITGMPIVV 137

Query: 134 YEP-GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKG 192
            +       E V KV    ++ E+L+ +E+ +  +   +++V  S    LE    GV+KG
Sbjct: 138 VDDFKAAVKEPVVKVLMNKEA-ERLVEVEKKLQKQLEGQLSVMRSKPFFLEFTEAGVTKG 196

Query: 193 HALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNA 252
            +L  + +KLG   ++ IA GD  ND  M+  AG G  MG+A   +K++     V  TN 
Sbjct: 197 TSLNQLIQKLGIKREEVIAMGDSYNDQAMIEFAGLGVAMGNAPDDIKEIAN--YVTDTNM 254

Query: 253 DDAVPHYLRKLYL 265
           +D V   + K  L
Sbjct: 255 NDGVAKVVEKFVL 267


>UniRef50_A9KKJ5 Cof-like hydrolase n=3 Tax=Clostridiales RepID=A9KKJ5_CLOPH
          Length = 275

 Score =  232 bits (593), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 71/269 (26%), Positives = 123/269 (45%), Gaps = 6/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            +V+A DLDGTL + +  ++   KETL+     G+  V A+GR  V +  +   LE+   
Sbjct: 3   IKVLALDLDGTLTNSEKKITLNTKETLQRAMEDGVTVVLASGRPLVGIKPLAKELELSKY 62

Query: 60  -SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y++  NG ++ D   G  ++   L+ +  + ++ V       +     +D    +   
Sbjct: 63  SGYILAYNGGQIIDCHTGKEVYQKVLNVERIASIYEVAKQFGVAMLTYDGEDIITEDDTD 122

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
           P  +R       +    E  +               HE+LLP+   +  ++GD +++ FS
Sbjct: 123 PYVLRECFINKVKVRKIEDIVSHVTYPVPKCLVVGEHEKLLPVRDYLKDKYGDELSIYFS 182

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LE+M  GV K  +LE +  +L  S ++ +A GDG+ND  ML  AG G  MG+A   
Sbjct: 183 EPFFLEIMPLGVEKSASLELLLNRLQLSREELMACGDGLNDITMLQYAGLGVAMGNACNE 242

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            K++     +  TN +D V   + +  LS
Sbjct: 243 AKEVSK--YITATNDEDGVAKAVNRFILS 269


>UniRef50_A3I239 Putative uncharacterized protein n=1 Tax=Algoriphagus sp. PR1
           RepID=A3I239_9SPHI
          Length = 272

 Score =  232 bits (592), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 118/272 (43%), Gaps = 13/272 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL-EIKS 60
            +   SD+DGTLL+ D  LSP  K  +    +     + A+ R    +  +  +L + + 
Sbjct: 3   IKAFCSDIDGTLLNADRDLSPRLKSVVNKFPS-DFPVILASSRMPNAMRHLVRDLQKPEQ 61

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            +I  NG  V   +G ++ +  +   + + +  +   N +I  ++Y+ ++W+  +     
Sbjct: 62  PLICYNGGYVISAEGEILDSVTIPVPLVAKILDLCK-NTNIHVSLYQGEDWYEEKDDYWS 120

Query: 121 MRFFKEAVFQYA------LYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
            R  +             + +       G  KV    DS E +  L   ++   G+ +++
Sbjct: 121 QREIRNTKTNCTWLPGNEVVQLWSKGDSGAHKVMCMGDSQE-ISWLFGELHFEHGNDLHL 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKK-LGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
             S+ T LE+    +SK   L  +      + ++  IAFGD  ND ++L   G G  +G+
Sbjct: 180 YRSSDTYLEIAPRSISKATGLIKILDHAFDFGMESVIAFGDNYNDIDLLQSVGYGVAVGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A   +K +    E+  TN +D V   L KL+L
Sbjct: 240 ARPEVKAVAK--EITTTNKEDGVAIVLEKLFL 269


>UniRef50_D1XVB8 Cof-like hydrolase n=1 Tax=Prevotella bivia JCVIHMP010
           RepID=D1XVB8_9BACT
          Length = 292

 Score =  232 bits (592), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 61/272 (22%), Positives = 115/272 (42%), Gaps = 13/272 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
           Y+++  DLDGTL +    ++P  KE L     +G+  V A+GR    +  + + L +   
Sbjct: 26  YKMIVLDLDGTLTNSKKVITPKTKEALIQAQKKGVRIVLASGRPTYGIKNLAEELCLNQH 85

Query: 59  KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM---- 113
             Y++  NG ++ D  +   +F   L  ++   L+        +    Y+          
Sbjct: 86  HGYILAFNGGKIIDCSNNETLFEQTLSPELVPTLYNSAMK-GGMQILTYQGKGIAATSTE 144

Query: 114 NRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
           +++  EE    K  +  Y+ +   ++ P  ++K     D    L  +E  +      +++
Sbjct: 145 DKYVKEEAFINKLPITLYSNFLEQIVYP--INKCLIVGDPTP-LHEVEIQLAKTLEGKMS 201

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V  S    LE +   V K  +L  + K  G   ++ IA GDG ND  M+  AG G  M +
Sbjct: 202 VYRSADYFLECVPLNVDKAQSLAKLLKLTGIKREEIIACGDGYNDLSMICFAGLGVAMAN 261

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A++ ++     + +  +N  D V   + K  L
Sbjct: 262 ANEDIRIQANYVTL-ASNEKDGVAEVVEKFLL 292


>UniRef50_Q3D5Y9 Hydrolase, haloacid dehalogenase-like family n=9 Tax=Streptococcus
           agalactiae RepID=Q3D5Y9_STRAG
          Length = 265

 Score =  232 bits (592), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 76/267 (28%), Positives = 138/267 (51%), Gaps = 9/267 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ SD+DGTL++ +  ++P  ++ +K + A+G  FV  + R    +  I + + I S
Sbjct: 1   MVRLIFSDIDGTLINSNFKVTPKTRQGIKQIVAQGATFVPISARMPEAITPIMEQIGIDS 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPD-IITNVYRDDEWFMNRHRPE 119
           Y+I+ NGA + D+    I +H +D  +A  +   V+ +   I  NVYR  EW+      E
Sbjct: 61  YIISYNGALIQDMQQKTIASHTMDGQVALQVCSYVSKHYSKIAWNVYRYHEWYSCDKENE 120

Query: 120 EMRFFKEAVFQYALYEPGLLEPEG---VSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
            ++  +E +      E  L+E E    + K+    +    +  LE  + A++   ++++ 
Sbjct: 121 WVQ-KEEEIVGLQSKEMSLMELEKQDRIHKLLLMGEPS-LMGELENTLKAQYP-HLSIAQ 177

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    +E+MA G+ KG + + +A  L  SL D IAFGD  ND  +L + GKG +MG+A +
Sbjct: 178 SAPYFIEIMAPGIEKGKSAKTLADYLDISLADSIAFGDNYNDLNLLEIVGKGFVMGNAPK 237

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKL 263
            L++      V   N +D + + L + 
Sbjct: 238 DLQERIGN--VTQDNDNDGIYYALVEY 262


>UniRef50_C2EN69 HAD family hydrolase n=7 Tax=Firmicutes RepID=C2EN69_9LACO
          Length = 272

 Score =  231 bits (591), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 73/273 (26%), Positives = 129/273 (47%), Gaps = 10/273 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A DLD TLL     +    K+ ++  T  G+ FV ATGR +  + Q  D + +K 
Sbjct: 1   MYKLIACDLDETLLDDHAHVCQRNKDAIEAATKLGVKFVPATGRGYNAIAQTLDEINLKD 60

Query: 61  ----YMITSNGARVHDLDGNLIFA-HNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I+ NG  + +  GN I     L  D A++L+  +    ++  +VY  D  ++  
Sbjct: 61  KANEYVISFNGGCITENKGNRIMKFQGLSWDKANELYQ-LGLKYNVCIHVYTKDMLYVYH 119

Query: 116 HRPEEMRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
              EE+ + K   A       +   L+ + ++KV +       L  +   I++   D ++
Sbjct: 120 ADEEELNYIKLRHAYQIIDDQDLDFLKGQEIAKVLYGNPDVPYLEKIANEISSSTKD-LD 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           VS+S+   LE    GV+KG  L  +A KLG  L++ +A GD  ND  M+  AG G  + +
Sbjct: 179 VSYSSNRYLEFNHQGVNKGAGLIWLANKLGIKLEETMALGDNFNDLSMIKAAGLGVGVAN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            + ++K+    +       +  V   + K  L+
Sbjct: 239 VNPQMKNECDFVT-NADYKEGGVGEAIEKFVLN 270


>UniRef50_Q97ES2 HAD superfamily hydrolase n=1 Tax=Clostridium acetobutylicum
           RepID=Q97ES2_CLOAB
          Length = 280

 Score =  231 bits (591), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 69/281 (24%), Positives = 125/281 (44%), Gaps = 26/281 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V  D+DGTLL+  H +S   KE ++   A+G++ V  TGR + +       + +KS 
Sbjct: 3   YKLVCIDMDGTLLNSKHCVSGETKEVIRKAYAKGVDIVITTGRIYANAAFYSKLIGVKSP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVV------------------NDNPDIIT 103
           +I SNGA +   D N+I+ + L  D  S +F V                   +    I+ 
Sbjct: 63  VIASNGAIIRGRDNNIIYKNVLSSDTLSRIFNVCSRLKGNITLHTHDSIICSSKFAYIVM 122

Query: 104 NVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQA 163
            V        N     ++++ K     Y+ Y  GL E   + K        +++  + + 
Sbjct: 123 WVIFIGSIIKNNENTLKIKYVK----NYSAYINGLKESNDIIKCEIIDKDVKKISAIREE 178

Query: 164 INARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLS 223
           +     + + V  S+   +EV +  VSKG+A++++A+  G   ++ I  GD  ND  M+ 
Sbjct: 179 LKRM--NDIEVVSSSRHNIEVTSKNVSKGNAIKSLAEFYGIKREEIITIGDSENDLSMIE 236

Query: 224 MAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             G G +M +  +  K L     +  TN ++ V   ++K  
Sbjct: 237 YGGLGVVMENGCESAKKLAD--YITDTNDNNGVAKVIKKFI 275


>UniRef50_C5NXD6 Phosphatase YidA n=1 Tax=Gemella haemolysans ATCC 10379
           RepID=C5NXD6_9BACL
          Length = 270

 Score =  231 bits (591), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 63/269 (23%), Positives = 126/269 (46%), Gaps = 7/269 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++V +D+D TLL+ D  +S   +E ++    + I  + A+GR    +  I ++L++ S
Sbjct: 1   MIKLVVTDIDDTLLNSDREISKKNREVIEECKKQDIKVILASGRPDFGMMSIVEDLQLDS 60

Query: 61  Y---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           Y   +++ NGAR+ +L    +I+   L  +    L  V  +N +     Y+  +   NR 
Sbjct: 61  YDNYLLSFNGARIANLKTNEVIYEKFLSPERIKFLIDVALEN-NCDILTYQGGKVLTNRD 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                        +  + E    + +  +         ++ + ++  +    GD   V+ 
Sbjct: 120 NEYARIESGLVSAELVISENMKDDIKEGAAKVIILKHPDEAVAVKDKLALELGDEYEVAM 179

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    +E+   G+SKG +L+++ KKLG + ++ +A GDG+ND  M+  AG G  + +A+ 
Sbjct: 180 SKPFFIELNDKGISKGVSLDSLCKKLGLTNENVMALGDGLNDLSMIEFAGMGVAVDNANP 239

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            LK+      +  +N +D   + + K  L
Sbjct: 240 TLKEAAN--FISKSNDEDGFAYAIEKFVL 266


>UniRef50_Q030F1 Predicted hydrolase of the HAD superfamily n=34 Tax=Lactobacillales
           RepID=Q030F1_LACLS
          Length = 281

 Score =  231 bits (591), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 56/267 (20%), Positives = 109/267 (40%), Gaps = 5/267 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIR---DNLEI 58
            +++A DLDGTLL+    +S   +  +     +G++ V  TGR  + +       + L+ 
Sbjct: 17  IKLIALDLDGTLLNSSKEISKENRLAIDAARQKGVHVVLTTGRPLIAIQPFLKTLEMLDF 76

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
           + + IT NG  V    G ++   +   D   ++   +     I  +V  +++ +M +   
Sbjct: 77  EDFSITFNGGLVQRNTGQILSKKSFTHDEILEI-KELTTKLGIPCDVLSEEKVYMTKSDV 135

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
                    +  +   +   +  + V     +C   E L      I   + +   +  + 
Sbjct: 136 VSQYDTLNKLLTFIKVDFDQVTLDVVYNKIVSCTDKELLDAQLSKIPESYFEEFEIFKTQ 195

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LE M  G++K + L  +  +L    ++ +A GD  ND  M+S AG G  M +A   +
Sbjct: 196 AKLLEFMPKGINKAYGLTQLTNQLNLGAENVMAMGDEANDLSMISWAGYGVAMANAVPAV 255

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K+    +    TN   AV H + +  L
Sbjct: 256 KEEA-RIISDLTNDQHAVAHMIERYVL 281


>UniRef50_C1P6V3 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36D1
           RepID=C1P6V3_BACCO
          Length = 285

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 71/287 (24%), Positives = 117/287 (40%), Gaps = 29/287 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D DGTLLS D T+S      ++ +  +G   V  +GR   D   I     +   +
Sbjct: 2   KLIAIDFDGTLLSDDGTISEENAGAIREVQEQGNIVVACSGRSLHDTRHILKKAGLDCPV 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE--- 119
           IT NGA ++D D   I    +   +  DL   +               + + + R     
Sbjct: 62  ITGNGAVIYDSD-QCILKLVMPDKVLDDLLPELEAQGYYYELYTNQGVYLLEKGRKRLES 120

Query: 120 ---------------------EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLL 158
                                E++  +  +  +  Y    L    V K+F      E+L 
Sbjct: 121 EMHSLHEKDETFSLEWAAGQIELQMRQYGIHYFHHYAELDLPHLEVYKIFVLSFHPERLK 180

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
            L   ++ R    ++++ S  T LE+    VSKGHAL+ +A+ L   L++ +A GD  ND
Sbjct: 181 QLRSWLSGR--QDLSMTTSGRTKLEIAHAEVSKGHALQFMARHLNIPLENTVAIGDNFND 238

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             M  +AG    MG+A +++K       V  T+  + V H LR   L
Sbjct: 239 LSMFEVAGISIAMGNAEEQVK--ARSTYVTKTHNKNGVAHALRTYIL 283


>UniRef50_A4VVF4 Predicted hydrolase of the HAD superfamily n=38 Tax=Streptococcus
           RepID=A4VVF4_STRSY
          Length = 271

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 64/273 (23%), Positives = 113/273 (41%), Gaps = 10/273 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTLL+    L     + +      G   V  TGR    V    + L   +
Sbjct: 1   MIKLIALDMDGTLLNEKKELMQPQIDAIHQAVEAGFKIVLCTGRPLAGVKPFVEQLGFDT 60

Query: 61  ---YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              ++I +NG   H   D +LI    L      D      +N D+  +++ ++++F+   
Sbjct: 61  EEEFIIVNNGCSTHSTKDWSLIDWEELSISDI-DYLSTFIENADVQISLFDEEDYFVLAE 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFF---TCDSHEQLLPLEQAINARWGDRVN 173
           +          +         L E +     FF          +   E   N     R +
Sbjct: 120 KANARVNLDAGLVGMTPQPIDLKEAQSGQYRFFEAMFVGEKVHIDAFENQHNPVLSKRYS 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              S    LE++  G SK   L+ +A +LG   ++ +A GD  ND EM+  AG G  MG+
Sbjct: 180 TVRSQDYLLEILPNGASKASGLKKLADRLGILPEEIMAMGDANNDLEMIEFAGLGIAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A++++K +    ++  TN ++ V   + K  L+
Sbjct: 240 ANEQVKAIAQ--DITDTNENNGVAKAIEKHILN 270


>UniRef50_B5CTA9 Putative uncharacterized protein n=4 Tax=Clostridiales
           RepID=B5CTA9_9FIRM
          Length = 279

 Score =  231 bits (590), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 62/268 (23%), Positives = 116/268 (43%), Gaps = 11/268 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL---EI 58
           YQV+  DLDGTL +    ++   ++ L  +   G   V A+GR    V  +   L   + 
Sbjct: 11  YQVIVLDLDGTLTNSKKEITEPTRQALIDIQKNGKTVVLASGRPINGVAPLAKQLRLQDF 70

Query: 59  KSYMITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYR-DDEWFMNRH 116
             YM++ NGARV    DG +I+   +  ++   +  +V    +   ++    D   ++  
Sbjct: 71  GGYMLSFNGARVTRCSDGKIIYNKQIPPEMIRPICDIVRSYAEQGVDLITYTDTTIISAI 130

Query: 117 RPEEMRFFKEAVFQYALYEPGLL---EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            P +    +  + +  +Y+P          ++K+       + L  L + +  ++   +N
Sbjct: 131 APNQYTRIESGINRMEIYQPDDFVSYIDFPINKLLVPG-PADVLQELMKLLKEKYHGLLN 189

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +  S    LE+M   + K H+L+ +   +G +    I  GDG ND  M+  AG G  M +
Sbjct: 190 IYLSEPYFLEIMPQNIDKAHSLQKLLNSIGLTADSMICCGDGFNDLSMIEYAGLGVAMEN 249

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLR 261
           A   +KD      +  +N +D V H + 
Sbjct: 250 AQPIIKDSAD--FITRSNDEDGVLHVVN 275


>UniRef50_D2LWT0 Cof-like hydrolase n=1 Tax=Bacillus cellulosilyticus DSM 2522
           RepID=D2LWT0_BACS4
          Length = 247

 Score =  231 bits (589), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 65/264 (24%), Positives = 121/264 (45%), Gaps = 23/264 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A D+DGTLL+ DH++S   +  +      G+  V +TGR  + +    ++L + SY
Sbjct: 4   IKLIALDMDGTLLNSDHSISDANRLAIMEAEQNGMTVVISTGRSILTLKPYIESLNLSSY 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           ++T NG+ + D  G +     L  D+   ++  +    D+       ++ + +    +E+
Sbjct: 64  IVTVNGSLIWDNKGEVFDQSELAPDLIKMMWD-LKKKYDLHFWAVTPEKVWRDEFPEDEI 122

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
              +   F Y +      E +   K  F   S +              DR+ ++ S    
Sbjct: 123 EAHEWLKFCYHI------EDDKTRKTVFEFLSKD--------------DRLEITNSNPVN 162

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+ A G++K  AL  + ++LG ++ + +A GD +ND  M+  AG G  MG+A   +KD 
Sbjct: 163 LEINAAGINKASALRKICEELGITMDNVLAMGDSLNDIAMIKEAGVGVAMGNAQPVVKDA 222

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                V   N +D V   ++K  L
Sbjct: 223 ADW--VTTKNNEDGVALGIKKFAL 244


>UniRef50_A1SVY5 Cof-like hydrolase n=4 Tax=Bacteria RepID=A1SVY5_PSYIN
          Length = 268

 Score =  231 bits (589), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 58/271 (21%), Positives = 112/271 (41%), Gaps = 8/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY++V  D+DGTLL+    ++   ++ +      GI  V A+GR    +    + L +  
Sbjct: 1   MYKLVVLDMDGTLLNSQKEITERVRKAINAAKDIGIKVVLASGRPIDGMSPALEALSLTT 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y++T N +   +     +I +  L    A DL+  ++    + T+ Y   +  +   
Sbjct: 61  VDDYVLTCNASLTLNAGSREVIRSEFLTGQDARDLY-HLSVKLGVNTHAYSAKQGLITPK 119

Query: 117 RPEEMRFFKE-AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             +      +    +  + +   LEP+         D  + L      +     ++ +++
Sbjct: 120 TSKYTEHEADINQIKINICDFTTLEPDHEMLKIMMIDEADLLTAAINRLPDSLQEKYSMA 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S     E M+    K + + A+A  LG++ ++ I  GD  ND EM+  AG G  M +A 
Sbjct: 180 QSAPFFYEFMSKKSGKANGVIALAAYLGFTQEEVICVGDAGNDLEMIQYAGLGIAMANAT 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K +     +  +N  D V H   K  L+
Sbjct: 240 DDVKAVAD--YITLSNDQDGVAHVFEKFILA 268


>UniRef50_P70947 Putative phosphatase yitU n=101 Tax=Firmicutes RepID=YITU_BACSU
          Length = 270

 Score =  231 bits (589), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 59/265 (22%), Positives = 107/265 (40%), Gaps = 7/265 (2%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A DLDGTLL  D T+S     T++ L   G     +TGR +         +E+ + ++
Sbjct: 7   LIALDLDGTLLKDDKTISENTLHTIQRLKDDGHYVCISTGRPYRSSSMYYQQMELTTPIV 66

Query: 64  TSNGARVHDLDGNLI--FAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
             NGA VH    +    +  +L  D+   L  +              D+ + + H    +
Sbjct: 67  NFNGAFVHHPQDDSWGRYHTSLPLDVVKQLVDISESYNVHNVLAEVIDDVYFHYHDEHLI 126

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
             F        + +      E V+ V       E +  +   ++    + ++        
Sbjct: 127 DAFNMNTTNVTVGDLRENLGEDVTSVLIHAK-EEDVPAIRSYLSDVHAEVIDHRRWAAPW 185

Query: 182 --LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +E++  G++K   L+ ++   G   +  IAFGD  ND EML  AG G  MG+    +K
Sbjct: 186 HVIEIIKSGMNKAVGLQKISDYYGVPRERIIAFGDEDNDLEMLEFAGCGVAMGNGIDAVK 245

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
            +        TN +D V  +L++ +
Sbjct: 246 QIANR--TTATNEEDGVARFLKEYF 268


>UniRef50_C2LPY8 HAD-superfamily hydrolase, subfamily IIB n=5 Tax=Streptococcus
           RepID=C2LPY8_STRSL
          Length = 269

 Score =  230 bits (588), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 114/269 (42%), Gaps = 7/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
            +++ SD+DGT+L+ +H +     E +  L    I FV A+ R  + +  I   L +  +
Sbjct: 4   IRLIISDIDGTILTSNHQVEEQLIEVMPELEKANIPFVLASARSPLGMQPIAHKLGLHDN 63

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVV-NDNPDIITNVYRDDEWFMNRHRPE 119
            +   NGA V + D  +I  H +D+    DL   +  D P +  N+Y   +W  N     
Sbjct: 64  PIACYNGALVLEGDRTII-QHPVDKAEIQDLLNYLSKDYPSVSVNIYSGKDWITNELDKW 122

Query: 120 EMRFFKEAVFQYALYE--PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
                        + E    + + E         D  E +  L Q + +    +     S
Sbjct: 123 SQLEGSITGESPIIKELQDTVSDSEPPIHKLLLIDEPEVIQDLHQKLLSMDFPQTAFYLS 182

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LEV A  VSK HAL  VAK     L+  +  GD  ND+ ML++AG G  MG+A + 
Sbjct: 183 KDNYLEVTAKHVSKEHALLEVAKYYDLPLEQVMTIGDNFNDSPMLALAGLGIAMGNAPEG 242

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +K+      V  +N +  V   + +  L+
Sbjct: 243 VKETANL--VTASNDEHGVAQAITEHVLN 269


>UniRef50_A5KNX9 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A5KNX9_9FIRM
          Length = 305

 Score =  230 bits (588), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 67/277 (24%), Positives = 115/277 (41%), Gaps = 19/277 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  DLDGTLL+    L+   +E L      GI  + ATGR  + V +        +Y
Sbjct: 28  IKMIGLDLDGTLLTDKKELTVRTREVLAKAIRSGIVVLVATGRPWMGVPEELREFPGMNY 87

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            +TSNGAR+ D   GN+I  H L    A     +     D +  VY D + +    + E 
Sbjct: 88  ALTSNGARIIDTRTGNVIEEHLLSVKSAKKALEICRKY-DTLQEVYFDGQGYAPAEKMEF 146

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVF------------FTCDSHEQLLPLEQAINARW 168
           +  + +    +       +  + + ++                D  E+    E+      
Sbjct: 147 VERYHKNPNMWEYMRKTRIPVDDIFELVDRENRGLDKTQALFADMSERKRAWEELAR--- 203

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
            + + +  S    +EV A GV+KG  L  +  +LG   ++ +AFGDG ND  ML   G G
Sbjct: 204 HEDLELVGSLRYNIEVNAAGVNKGTGLVNLGSRLGIKREEIMAFGDGDNDTVMLKEVGFG 263

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             M +   ++K+      +  +N +D V   + +  L
Sbjct: 264 VAMANGEPQVKEAAD--YITLSNEEDGVAQAIERFVL 298


>UniRef50_Q5WG82 HAD superfamily hydrolase n=1 Tax=Bacillus clausii KSM-K16
           RepID=Q5WG82_BACSK
          Length = 246

 Score =  230 bits (588), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 64/264 (24%), Positives = 117/264 (44%), Gaps = 24/264 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A D+DGTLL+ +  ++ + K  ++     GI  V  TGR          +L++ S+
Sbjct: 4   IKMIALDIDGTLLNDNKEITSWTKNQIRKAQHAGITVVLCTGRPFPHCHTYIQDLQLHSH 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            IT NG +++ +D +++  H  D    ++L+            +   + ++     PE  
Sbjct: 64  SITCNGGQIYAVDHSVMIEHLFDAATLANLYHFAQGLGMNTWTISTKEAYY--NDLPENC 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
             ++                    K   +    E L  + + + +   D V VS  T   
Sbjct: 122 SAYQ------------------WLKFSCSHKDEEVLNKMAEKVQSI--DGVEVSNRTAFT 161

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +EV   GV+K  ALE V +KLG ++K  +A GD +ND +M+  AG G  MG+A + ++ +
Sbjct: 162 VEVNPTGVNKAAALEWVCEKLGITMKHVMAIGDSLNDIKMIQSAGIGIAMGNAQKAVQQV 221

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                +  TN +D V   + K   
Sbjct: 222 ADA--ITDTNNNDGVGKAIEKFIF 243


>UniRef50_Q0STC6 HAD hydrolase, IIB family n=9 Tax=Clostridium perfringens
           RepID=Q0STC6_CLOPS
          Length = 277

 Score =  230 bits (588), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 63/278 (22%), Positives = 124/278 (44%), Gaps = 20/278 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+    +S   +  LK    +G++ +  TGR+  +     + L +   
Sbjct: 3   YKMICIDMDGTLLNSKKVVSEENRIALKKAYEKGVHIIICTGRNPKNAIYFSEFLGVNCA 62

Query: 62  MITSNGARVHDLDGNLIFAHN-LDRDIASDLFGVVNDNPDIITNVYRDDEWF-------- 112
           +I +NGA V D D +++ + + L+ +   D+  +  +   +I + +  D  +        
Sbjct: 63  VIANNGAWVIDEDKDIVISKDVLNENQCMDIMNICKEYK-VIPSFHSKDSVYWPSRFRKY 121

Query: 113 -----MNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
                +N+  PE+ R     V +   +   + +   + K      +  +L  + + +  +
Sbjct: 122 LCDIILNKKIPEKYRVKNIYVKEKEEWRE-VFKSNNIGKCIIIELNTSKLKKIRENLIKK 180

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
                 ++ S    LEV   GVSKG A+EA+A++     ++ I  GD  ND  M++ AG 
Sbjct: 181 --GNYEITQSGRYALEVNNKGVSKGRAVEALAEEYKIKREEIICIGDNENDLSMINYAGL 238

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G  MG+A   LK       +  +N  + V   + +  L
Sbjct: 239 GVAMGNAIDSLKKKAD--YITESNDKNGVAKVIYEFVL 274


>UniRef50_C5EF13 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C5EF13_9FIRM
          Length = 273

 Score =  230 bits (587), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 67/266 (25%), Positives = 119/266 (44%), Gaps = 10/266 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ SD+DGTLL+  H +    ++ +  L   G+ FV  + R    +  I+  +  ++ 
Sbjct: 10  YKMIFSDIDGTLLNSGHQVPEPTRKKILELEKEGVPFVLVSARMPEGMTTIQAMIGNRAP 69

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVV-NDNPDIITNVYRDDEWFMNRHRPEE 120
           M+  +GA + D DGN +++  +D D+A  +  ++  + P+I  N Y    W ++      
Sbjct: 70  MVCYSGALIRDADGNTMYSCQMDLDLAVRIKDLIGKEFPEICCNTYGGSRWVVDDDSSPW 129

Query: 121 MRFFKEAVFQYALYEPGLLE----PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
           +R  +E +         + E      GV K F      E +  LE+ +   + D ++++ 
Sbjct: 130 VR-KEEEITGLKAMNGDIREVFTADRGVHK-FLLMGQEEAVQGLEKRLKEHFPD-LSIAS 186

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S+   LEVM G VSK   +  +    G  L + IAFGDG ND +ML        M +A  
Sbjct: 187 SSPVYLEVMDGRVSKSRGVGFLCSHYGVGLDEVIAFGDGCNDMDMLRAVKNSYAMANAPL 246

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRK 262
            ++       V   N        L +
Sbjct: 247 GVRRSAAH--VTLDNDHQGFLAALEE 270


>UniRef50_C7RFK7 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7RFK7_ANAPD
          Length = 265

 Score =  230 bits (587), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 77/268 (28%), Positives = 120/268 (44%), Gaps = 9/268 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY- 61
           +++  D+DGTL++    ++   +E L      G   V  TGR       + + LE   Y 
Sbjct: 2   KLIGVDVDGTLVNSKRVITERTREALISAMKAGHKVVIVTGRPTAGARNLAEALEFDKYG 61

Query: 62  --MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             + + NG  + D   G ++  H +D DIA ++  +  D P + T V   D  F  +  P
Sbjct: 62  GLISSFNGGAITDFATGKVLANHEMDHDIAVEMIKLAKDLP-LETMVPYMDTVFSPKIGP 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPE-GVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
                 +    +    E      +  V+K+ F  D  + +      I  R+GD      S
Sbjct: 121 YTEGEARTLRMEAKEVEDLDQTIDFPVNKILFAADP-DLIDEPTSKIKERFGDLTEQVKS 179

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
                EVM  G+SKG++L  +AK      KD IAFGD MND  M+  AG G  MG+A  +
Sbjct: 180 ARFYYEVMPMGLSKGNSLLEIAKIFNIDQKDIIAFGDEMNDETMIEAAGVGVAMGNAVSK 239

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +K++     V  TN +D + +YL K  L
Sbjct: 240 IKEIAD--YVTLTNDEDGIAYYLDKFIL 265


>UniRef50_C7TGI6 Hydrolase of the HAD superfamily n=9 Tax=Lactobacillus
           RepID=C7TGI6_LACRL
          Length = 275

 Score =  230 bits (587), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 76/271 (28%), Positives = 106/271 (39%), Gaps = 10/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A DLD TLL+    LSP   E L+   A GI  V  TGR    V    D L +  
Sbjct: 4   MIRLIAVDLDDTLLNSHKQLSPATVEGLQTALASGIKVVPCTGRPLPGVRTTLDALGLHG 63

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDL--FGVVNDNPDIITNVYR--DDEWFM 113
              Y+I   G  V    G +I    ++     D   F        I +NV     D +  
Sbjct: 64  DDQYVIVQGGGVVQSTSGKIIAQKFMNHQDYKDFSTFATSVSAAGIDSNVLTPAGDVYTA 123

Query: 114 NRHRPEEMRFFK-EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
           +R+          E      + EP  +  + V          EQ+  ++    A +G+R 
Sbjct: 124 DRNISRYTVLQAWENHAGIKVREPQEMPDDFVIAKGILLGEPEQVANIQPQAEAEFGNRF 183

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            V  S    LE+M  GV KG  L  + + LG    D IAFGD  ND +M   AG    M 
Sbjct: 184 TVIRSMPFMLEIMPQGVDKGWGLAQLTQHLGLKPADVIAFGDEHNDLDMFDFAGVSVAMA 243

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           +    +K       V  +N DD V   L+  
Sbjct: 244 NGQNVVKSHAD--YVTASNDDDGVVKALKHF 272


>UniRef50_C4IB07 Cof protein n=1 Tax=Clostridium butyricum E4 str. BoNT E BL5262
           RepID=C4IB07_CLOBU
          Length = 266

 Score =  229 bits (586), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 57/266 (21%), Positives = 125/266 (46%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           ++++ SD+DGTLL+  H +S   KE+L LL    I FV  + R    + +++  + + S 
Sbjct: 4   FKIIFSDIDGTLLNSSHEVSEKNKESLVLLNKLNIPFVLVSARMPQGIKKVQKEINVNSP 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDN-PDIITNVYRDDEWFMNRHRPEE 120
           ++  +G  V D +G  + +  +  + A ++   ++    ++ T+ Y  D+W  +  + E 
Sbjct: 64  IVCYSGGLVIDSNGKYLMSIGIRIEKAQEIKNYIDGKWKNVSTSYYSYDKWIADNKKDEW 123

Query: 121 MRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           +    +      ++     + E   V          + +  ++ +I+ ++ + +++  S 
Sbjct: 124 IAQESDITSVNPIFGKIQDICEKNSVVHKILCMGDSKVIDEIKDSISEKY-EGLSIYKSK 182

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
            T LE+M    +K  A++ +       ++D I+ GD  ND +M+  AG G  M +A   +
Sbjct: 183 DTYLEIMELDATKSGAMKVLCDSFNIKMEDTISIGDNYNDVDMIKAAGNGIAMANAPDEV 242

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           K +    E+  +N +D V   + K +
Sbjct: 243 KRISN--ELTSSNDNDGVAEVIYKYF 266


>UniRef50_A0R0M1 Cof protein n=3 Tax=Bacteria RepID=A0R0M1_MYCS2
          Length = 270

 Score =  229 bits (586), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 57/265 (21%), Positives = 108/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++ +D+DGTL++ D  L+      +  L   GI F   +GR    + ++ + L + + 
Sbjct: 8   IRLLLADVDGTLVTHDKVLTHRTLAAVAKLREAGILFAVTSGRPPRGMSKLIEPLGLTTP 67

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRHRPEE 120
           +   NG      D ++I    +  D+ + +   + D   +   VYR  +W + + H P  
Sbjct: 68  LAAFNGGLFVRPDLSVIERRMISDDVTAAVIEQL-DTDGLTVWVYRGADWLVPDPHGPHV 126

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            R  +   F     E       GVSK+    D H+ +      +  R+ D V+ + S   
Sbjct: 127 AREARTVGFGPTPIESYPPISRGVSKIVGVSDDHDAVRKAAARLRERFADHVSAATSQPY 186

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            ++V     +KG  +  ++     + +     GD  ND  M   +G    MG+A   ++ 
Sbjct: 187 YVDVTHPDANKGAVVSFLSAAYDIATESIATIGDMANDVAMFRKSGLSIAMGNAGDEVRR 246

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 V  +NADD     + +  L
Sbjct: 247 AA--RCVTASNADDGFADAVERFVL 269


>UniRef50_C5D2V8 Cof-like hydrolase n=3 Tax=Geobacillus RepID=C5D2V8_GEOSW
          Length = 281

 Score =  229 bits (586), Expect = 6e-59,   Method: Composition-based stats.
 Identities = 65/282 (23%), Positives = 111/282 (39%), Gaps = 25/282 (8%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A D+DGTLL+ +  +S   KE +     +G      TGR + D      +  +   ++
Sbjct: 2   LIALDMDGTLLNSNGQVSRRNKEAIVTAQKQGHIVAIVTGRAYKDARAPLRDAGLVCPIM 61

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRF 123
           + NGA +   DG ++    LD++        V   PD+   +Y  D  ++  H    +  
Sbjct: 62  SLNGAVMTLEDGTVLGDVPLDKEKLIPALEWVRAQPDLYCEIYTGDAVYVGLHNRAHLEA 121

Query: 124 FKEAVFQYALYEPGLLEP----------EGV-----------SKVFFTCDSHEQLLPLEQ 162
             E     A     ++E           + +            KV       E+L     
Sbjct: 122 MAEKASDIAPELKRIVEKQFQQARVTYVDDIRAIWEERQTVFYKVLIFSLDQERLQEAAA 181

Query: 163 AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
              A  G  + V+ S    +E+     +KG AL  +A   G  +KD + FGD  ND  M 
Sbjct: 182 QFAAISG--ITVTSSHPNNIEINHEQATKGEALVKLAAHYGIDMKDTVVFGDSHNDLSMF 239

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ++AG    M +A   LK++     V  ++ +D V   L +L 
Sbjct: 240 AVAGYRVAMENAAPGLKEVSD--MVTASHEEDGVAVVLEELI 279


>UniRef50_C6VMV1 HAD superfamily hydrolase n=10 Tax=Lactobacillales
           RepID=C6VMV1_LACPJ
          Length = 272

 Score =  229 bits (585), Expect = 7e-59,   Method: Composition-based stats.
 Identities = 59/269 (21%), Positives = 112/269 (41%), Gaps = 10/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            +++A D+DGTL++    ++   K+ +K+   + I  V  TGR    V  +   LE+ + 
Sbjct: 5   IKMIAIDIDGTLVNSKKQVTLRVKQAIKMAKEKKIKVVICTGRPLTGVKALLQELELDAQ 64

Query: 61  ---YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y++   GA  +   G LI    +  +   DL   +     +  +   +D  +     
Sbjct: 65  DDQYVVCFGGAATYTTSGELIDERPISYEDYIDL-EALARKLRLHFHAVSEDRLYTADRN 123

Query: 118 PEEMRFFKEAVFQ--YALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQ-AINARWGDRVNV 174
             +   ++  +     +   P  +    + K  +  +       ++Q  +      +V  
Sbjct: 124 IGDYTLYEANLVSMGISYRTPEEMRNIKLIKSMYVDEPEVLDAAIKQQKLFEPLKKQVTF 183

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           + S     E  A GVSKG+AL+ + +KL  +  + +A GD  ND  M+  AG G  MG+A
Sbjct: 184 TKSAPFYYEANANGVSKGNALQVLCEKLSLTAANVMAIGDEANDLSMIKFAGHGVAMGNA 243

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKL 263
              +K +  E+ V   N  D V   +  +
Sbjct: 244 IPEVKQVADEITV--DNEHDGVAKAIEAI 270


>UniRef50_B9CKY2 Phosphatase YidA n=1 Tax=Atopobium rimae ATCC 49626
           RepID=B9CKY2_9ACTN
          Length = 273

 Score =  229 bits (585), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 69/272 (25%), Positives = 109/272 (40%), Gaps = 9/272 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
           Y+++ASDLD TLL  +H L    +E +     +G+ FV A+GR++  +      L +   
Sbjct: 4   YKLIASDLDETLLDSEHCLPKNVREAVLAARKKGVKFVPASGRNYQSIQVTLRELGLYDQ 63

Query: 59  -KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y I+ N   +  + D ++I    +  + A+++        D+  +VY   + +    
Sbjct: 64  PDEYTISFNSGIITENKDNHIISMEGISHEFANEILQRALTLGDLCVHVYTAHKIWAWNV 123

Query: 117 RPEEMRFFKEAVFQYALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
              E  +  +        EP L  L  E + K          L  L         D ++V
Sbjct: 124 PEIERFYTSKLQKMDETTEPNLAFLAGEKIIKCLVMNTDAAYLHRLAAEWQDITED-IDV 182

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           SFS    LE    G++KG  L  +   L    KD IA GD  ND  M+  AG G  M + 
Sbjct: 183 SFSANRYLEFNKKGINKGTGLVRLGHILNIPTKDIIAIGDNYNDLPMIKTAGLGVFMANT 242

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            + LK     +     N    V   + K  LS
Sbjct: 243 PEELKSQADYVT-TLDNNAGGVAEVIEKFVLS 273


>UniRef50_C0R158 Putative hydrolase n=1 Tax=Brachyspira hyodysenteriae WA1
           RepID=C0R158_BRAHW
          Length = 267

 Score =  229 bits (585), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 71/261 (27%), Positives = 126/261 (48%), Gaps = 5/261 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            Q++A+DLDGTLL+ +H +S Y K  +K  + +GI  + +TGR      +   +L+I + 
Sbjct: 4   IQLIATDLDGTLLNNNHQISEYNKNIIKAASKKGIKTILSTGRPTSAAIKFLYDLDIDTE 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+ NGA + D + N+I+  NL+  I  +L  +     +I    +  D W +     +  
Sbjct: 64  LISFNGAMITDKNSNIIYQENLNPKIGIELINIAKKY-NIYHQGFLGDRWNIGFFDNKWT 122

Query: 122 RFF-KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            F+   A     +     +E    SK  F  ++H  L  + + +N  +G+ +  +FS   
Sbjct: 123 NFYISIAQIDNYIIGFDNIEDFSFSKFMFIGENH-ILKNIAEELNRTFGNSIYYAFSRPV 181

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LEV +   SK +AL+ +A K   +  + +AFGD  ND EML   G    + +A   +K 
Sbjct: 182 YLEVHSPNASKANALKYLADKYNINSDNIMAFGDNNNDLEMLEFVGISVAVENAEDIVK- 240

Query: 241 LHPELEVIGTNADDAVPHYLR 261
               L    +N ++ V  ++ 
Sbjct: 241 -LKSLYTTKSNEENGVGIFIN 260


>UniRef50_C0X6C9 HAD superfamily hydrolase n=22 Tax=Enterococcus faecalis
           RepID=C0X6C9_ENTFA
          Length = 277

 Score =  229 bits (585), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 66/275 (24%), Positives = 122/275 (44%), Gaps = 20/275 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + +  D+DGTLL+ +  +SP  ++ L     +G++ + A+GR    +  + D LE+  Y
Sbjct: 3   IKAIVMDIDGTLLTSEKKISPKTRQALVAAQKQGLSLILASGRPTNGMRPLADELEMAHY 62

Query: 62  ---MITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              +++ NGA V H      +F   + + ++  +   +    D+I  +  +   ++N   
Sbjct: 63  NGHLLSYNGACVTHHGSQQQLFNQTISKSLSQQILEHLKQF-DVIPMINDETFMYVNDVF 121

Query: 118 PEEMRF---------FKEAVFQYALYEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAIN 165
              +           ++     + L E   L       ++K+    +    L    +AI 
Sbjct: 122 HHTLHLETGDFNIIEYESRGGNFQLCEWHDLAARLNFPLNKILIAGEPA-YLQKYHEAIY 180

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
           A + + V  +FS     E  A  + K  +LE +  +LG + ++ IAFGDG ND  ML  A
Sbjct: 181 APFKETVTAAFSAPFYFEFTAKNIDKARSLEKLTLQLGIAAEEVIAFGDGHNDYTMLEWA 240

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
           G G  M +A + LK +    EV  +N +D +   L
Sbjct: 241 GTGIAMENAVEELKSIA--TEVTLSNDNDGIAVAL 273


>UniRef50_C6IVB2 Predicted protein n=3 Tax=Bacillales RepID=C6IVB2_9BACL
          Length = 267

 Score =  229 bits (585), Expect = 9e-59,   Method: Composition-based stats.
 Identities = 62/267 (23%), Positives = 108/267 (40%), Gaps = 7/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+DGTLL+ DH L+P   ET++ +  +G  FV  TGR           + +  Y
Sbjct: 3   YKLIALDVDGTLLTDDHVLTPGTIETIRAIAEQGTEFVLCTGRAPRSSIPYMREIGLDGY 62

Query: 62  MITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR--P 118
           +I  NGA   D+    ++    ++             + ++  +V      ++       
Sbjct: 63  VICHNGAATVDVRTEEVVHEFAMNPHGLEPYMEYCRKH-NVHFDVNTTFALYVENLAGLT 121

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           +E        F      P   +       F      E+L  +    +  W    N+  S 
Sbjct: 122 QETLDVYHQFFMEPEDMPAWADFTKPIVKFTAAGGMEELDRVYADWSQ-WTQEFNMLRSG 180

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              +++M    SKG AL  +A+K G   ++ +A G+  ND  ML+ AG G  M ++   +
Sbjct: 181 DFFIDLMHKDASKGAALRKLAEKRGIPAENVMAIGNYYNDITMLTYAGLGVAMDNSPLDV 240

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K       V  +N ++ V   L K  L
Sbjct: 241 KAAADA--VTASNNEEGVKRALEKYCL 265


>UniRef50_C5RAW2 HAD superfamily hydrolase n=1 Tax=Weissella paramesenteroides ATCC
           33313 RepID=C5RAW2_WEIPA
          Length = 278

 Score =  229 bits (585), Expect = 9e-59,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 108/272 (39%), Gaps = 11/272 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++  D+D TL++ +  ++P  K+ L+  T +G+  V ATGR    V      L +   
Sbjct: 3   IKLITIDIDDTLVNSEKQITPRVKQALQTATNQGVKVVLATGRPLSGVQDYLTQLHLANQ 62

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              + IT NG+ V    G  +  H L        F  + +  +    V            
Sbjct: 63  SDQFAITYNGSVVQTTAGEQLGGHELSLADYKK-FKAIAEKYNSYIQVESLSYAITANTM 121

Query: 118 PEEMRFFKEAVFQYALY---EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                  +  + +  L       +   E   K  F  D  E++  L + +     D   +
Sbjct: 122 VNRFANGENNMVRMPLKFQPVSDMTTDEHYVKFMFI-DEAEKIDELAEHMPQELKDEYYI 180

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             ST   LEVM    +KG+ L+ +A KLG  + + +A GD  ND  M++ +G G  M +A
Sbjct: 181 VKSTPNFLEVMHKQSTKGNGLQLLADKLGIDMSETMALGDQHNDLTMIAASGIGVAMANA 240

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              +K       +  +  +D V   + K  L+
Sbjct: 241 VPEVKATAD--VMTTSQNEDGVGLAVEKWVLN 270


>UniRef50_UPI000196AEDD hypothetical protein CATMIT_00603 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196AEDD
          Length = 275

 Score =  229 bits (584), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 67/269 (24%), Positives = 122/269 (45%), Gaps = 13/269 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++A DLDGTL + ++ ++   +ETL      G   V A+GR    +      LE++  
Sbjct: 3   YKLIALDLDGTLKNSENKITDATRETLIKAQQLGATVVLASGRPTPGLRHEAAALELEKY 62

Query: 60  -SYMITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NGA+V D      +F   L  + A   +     + ++    Y DD  +     
Sbjct: 63  EGYLLSFNGAKVMDAKTRQTMFEQRLTVEQAKKAYDEAKKH-NLAIMTYYDDAVYTEDVD 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEP---EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
            + +      +    + +    +    + ++KV  T D       LE   +A  G  +++
Sbjct: 122 DQYVNIEGH-INDIEIKKAESFKSILRDPINKVLCTGDPEHVASVLEDYKSAFLG--LSI 178

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    +EVMA  + K  +L+ + K L  + ++ IAFGDG ND  ++  AG G  M +A
Sbjct: 179 YRSAPFFIEVMAPNIDKAASLDKLVKMLHLTKEEVIAFGDGFNDLSLIEYAGCGVAMANA 238

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKL 263
              +K+      V  +N +D + + L+KL
Sbjct: 239 VDEVKERAD--VVTLSNDEDGIAYMLKKL 265


>UniRef50_C8P4G9 Cof family protein n=1 Tax=Lactobacillus antri DSM 16041
           RepID=C8P4G9_9LACO
          Length = 274

 Score =  229 bits (584), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 59/274 (21%), Positives = 107/274 (39%), Gaps = 12/274 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            ++VA D+DGTL++    ++P     +K  + +G+  V  TGR    V      L +   
Sbjct: 3   IKMVAIDIDGTLINDQREITPKTVAAIKKASQQGVKIVLCTGRPMTGVRAYLKQLGLNNR 62

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y+++ NG       G ++   +L  +  +D          + + +   D  +     
Sbjct: 63  DDEYVVSFNGGLAQTTSGKVMVDESLSFNDYADWENYCLK-EGVHSQLETRDYIYTTNQD 121

Query: 118 PEEMRFFKEAVFQYAL-----YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
             +   ++  +    +      E   +  + V       D  E +      +      R 
Sbjct: 122 ISKYTVYESELVDMPIRYRPLDEMSRIRDQYVIAKAMMVDEKEVIDRALADLPEELASRF 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           ++  S    LE M  GVSKG AL+ + ++LG    + +A G+  ND  ML  AG G  MG
Sbjct: 182 SIVRSEDFYLEFMRKGVSKGQALDMLCQELGIGASEVMALGNAQNDNSMLEFAGHGVAMG 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           ++ +  K L    +V   N  D V   + K   +
Sbjct: 242 NSVE--KTLAIADDVTADNNHDGVAAAIDKYVFT 273


>UniRef50_A6BG65 Putative uncharacterized protein n=5 Tax=Clostridiales
           RepID=A6BG65_9FIRM
          Length = 272

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 61/271 (22%), Positives = 116/271 (42%), Gaps = 12/271 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           YQ++  DLDGTL +    ++    E L  +   G   V A+GR    V  + + L ++ Y
Sbjct: 3   YQILVLDLDGTLTNSKKEITQPTLEALIEIQEAGKKVVLASGRPTQGVMPLAEQLHLEDY 62

Query: 62  ---MITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDD-EWFMNRH 116
              +++ NG R+ D      I+   L  D    ++  V        +V     E  ++  
Sbjct: 63  GSYILSFNGGRITDCRTKQAIYNKILPADCIQGVYKTVRKYASQGIDVLTYTPEHILSGI 122

Query: 117 RPEEMRFFKEAVFQYALYE--PGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
           +  +    +  + Q  + +     L+  P+  +K   T D    L  + + ++ ++   +
Sbjct: 123 KSNQYTELESRINQMPVIDASENFLDCVPDDPNKFLVTGDPA-VLDQIRKELSKQFHSYL 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           +V  S    +EVM  G+ K H+L  +   +G + +  I  GDG ND  M+  AG G  M 
Sbjct: 182 SVYCSDPFFVEVMPAGIDKAHSLLKLLTSIGLTTEQMICCGDGYNDLTMIETAGLGVAMA 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           +A   +++      +  +N +D V H + + 
Sbjct: 242 NAQPAVRETAD--YITKSNDEDGVLHVINEF 270


>UniRef50_D0BM40 Cof family protein n=2 Tax=Granulicatella RepID=D0BM40_9LACT
          Length = 272

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 69/272 (25%), Positives = 114/272 (41%), Gaps = 12/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGIN--FVFATGRHHVDVGQIRDNLEI 58
           M +++A D+DGTLL+    L    K+  K    +      V  TGR    +     +L  
Sbjct: 1   MIKLIAIDMDGTLLNSKKQLLEETKQYFKEFHHKDTETLLVLCTGRPETGIRPYLKDLGY 60

Query: 59  ---KSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN 114
                Y+I+ NGA +++   GN I    +D         +  ++ DI       D ++  
Sbjct: 61  LEENHYIISQNGANIYESQTGNRIMDAFVDSSAIQKWIQLGKEH-DISVMGGGVDYYYSF 119

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEP--EGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
              P E   +   +    +    + E       K+    D  EQL   E+ I   W D  
Sbjct: 120 DQEPTEWMEYDVKIINGEIKRITIEESLTTDFYKILLLGD-EEQLNEFEKMIPDSWRDEF 178

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            V  S    +EV+  G++K + L+ +A+KL  +  +  A GD  ND EML  AG    MG
Sbjct: 179 YVVRSQKYLIEVLKKGINKAYGLKKLAQKLNITRNEIAAIGDAANDIEMLQYAGLAIAMG 238

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A + +K+L     V  TN ++ V   + ++ 
Sbjct: 239 NATEEVKNLCD--IVTDTNENNGVIKAIERVI 268


>UniRef50_C7ND82 Cof-like hydrolase n=4 Tax=Leptotrichia RepID=C7ND82_LEPBD
          Length = 270

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 87/268 (32%), Positives = 145/268 (54%), Gaps = 4/268 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M++ + SDLDGTLL+ +H +S + +ET+KLL  +GI F  ATGR+++   +  D L +K 
Sbjct: 1   MFKAIVSDLDGTLLNAEHKVSEFTRETVKLLLQKGIKFYIATGRNYLGAKEAMDELGVKI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVND--NPDIITNVYRDDEWFMNRHRP 118
            +ITS+G+   D +GN IF++ L R+    +  +       DII   Y    WF+     
Sbjct: 61  PLITSHGSAAFDENGNEIFSNRLKREYLDKVLNIDYKAFGKDIIITGYSGPNWFVTEDLR 120

Query: 119 EEMRFFKEAVFQYAL-YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR-VNVSF 176
           E     K    +Y     P   +    +K+FF  + H++LL LE  I    G+  +++ F
Sbjct: 121 EYFYNKKPDRTRYPKQITPSEFKKHDFAKIFFLGEDHDELLELENEIKKVIGEENISLLF 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           +    LEV     +K  A E V ++ G +LKD ++FGDG+ND E+++  G G  M ++  
Sbjct: 181 ANEGSLEVFPADCNKAKAAEVVLERDGLTLKDAVSFGDGLNDYELITETGLGFAMENSIY 240

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            L +   + EVI +NA+D +   +R+++
Sbjct: 241 LLLEKLTDTEVIESNANDGMAKKVREIF 268


>UniRef50_B9DRH4 Haloacid dehalogenase-like hydrolase n=11 Tax=Streptococcus
           RepID=B9DRH4_STRU0
          Length = 275

 Score =  228 bits (583), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 62/271 (22%), Positives = 106/271 (39%), Gaps = 8/271 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++A DLDGTL + + T+S   K  ++  +A+G+  V  TGR    +G + + L +   
Sbjct: 4   IKLLALDLDGTLFNAEKTISDANKLAIQKASAKGVKIVITTGRPLAAIGNVLEELGLTSD 63

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             Y IT NG  V    G ++   +L  +  + +   + +N  + T++  + + +    + 
Sbjct: 64  DDYCITFNGGLVQRCTGQILDKSSLSYEEVATVHQHL-ENLALPTDILSEGKVYSIPSKD 122

Query: 119 EEMRFFKEAVFQYALYEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                +  A       E   LE      V     T    + L      +     +     
Sbjct: 123 GRHSQYHLANPLLQFIEINSLEDLPKNIVYNKIVTVTDADFLDQQLSLLPPSTFEAFESF 182

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S     EVM  GV K   L+ +   L    K+ +A GD  ND  ML  +G G  M +A 
Sbjct: 183 KSRDIIFEVMPKGVHKAFGLQLLCSHLKIEAKEVMAMGDEANDFTMLEWSGLGVAMANAV 242

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              K +   +    TN    V   + K  L+
Sbjct: 243 AEAKQIADAVT-SQTNDQSGVAEAIEKYILN 272


>UniRef50_B0P1S7 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P1S7_9CLOT
          Length = 270

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 77/271 (28%), Positives = 115/271 (42%), Gaps = 14/271 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLDGTL +    ++      +      GI    A+GR    +   RD L++  +
Sbjct: 3   YKLIAVDLDGTLYNDQLKITSDTLNAMIEAQEMGIRIALASGRPLPGLFHARDLLKLNEH 62

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              ++  NG +V D     +++   +  D+A +L   + D P    N   DD   +    
Sbjct: 63  HGMLVAYNGGKVVDTTTNEVLYDKYIQDDLAMELLEHLKDYP---VNPIIDDGKVLYVTD 119

Query: 118 PEEMRFFKEAVFQYALYE--PGLLEPEGV--SKVFFTCDSHEQLLPLEQAINARWGDRVN 173
               R  +EA+     Y   P L E      +K+    D  +    LE  I   + D+V 
Sbjct: 120 KNGYRVKEEALNDSMEYVEVPSLTEHLDFHLNKILTAVDPQKTYDVLE-TIGMPFRDQVT 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              +    +E +  G SK   L  V K LG    + IAFGD  ND EM+  AG G  MG+
Sbjct: 179 FVRTAPYYIEAIPVGTSKASGLSNVCKGLGIDPSEVIAFGDAENDLEMIQFAGHGVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           A   LKD     EV  TN +D + H L  L 
Sbjct: 239 ACDALKDAAD--EVTLTNNEDGIAHTLNHLL 267


>UniRef50_A5CYL3 Predicted hydrolase n=5 Tax=Clostridia RepID=A5CYL3_PELTS
          Length = 274

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 68/265 (25%), Positives = 108/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           +++VA D+D TLLS D  L+   +E +  + A G+ F  +TGR +         L +   
Sbjct: 13  FKLVAVDMDDTLLSRDLKLTGRVREAVAAVRAAGVYFTISTGRMYRSALPFARELGLNIP 72

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT  GA V +   G L+    L    A ++   +++      N Y DD   + R  PE 
Sbjct: 73  LITYQGALVKNSHTGELVLYRPLPLARAREIIARIHE-LGYHLNGYLDDRLLVERDTPEG 131

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            R+   +  +  +    L   +       T      L  L   +   +  +V++  S   
Sbjct: 132 RRYAAMSGVEAEIVGDLLEYLDRDPIKVLTIAEEPLLDRLSAELTPLYRGKVHIVKSKPH 191

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE      +KG AL  +A   G   ++ +A GD  ND EML  AG G  + +A + +K 
Sbjct: 192 FLEFSHPQATKGDALAYLAGCFGVKREEVMAVGDSYNDLEMLEYAGLGVAVANAREDVKK 251

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 V      D V   L K  L
Sbjct: 252 KA--GYVTSAAYGDGVVEALEKFVL 274


>UniRef50_A8HYJ4 Haloacid dehalogenase-like hydrolase n=1 Tax=Chlamydomonas
           reinhardtii RepID=A8HYJ4_CHLRE
          Length = 323

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 73/270 (27%), Positives = 116/270 (42%), Gaps = 10/270 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATG--RHHVDVGQIRDNLEIK 59
            +++ +D+DGTLL     LSP  +  +K   A G+  V ATG  R       +   L++ 
Sbjct: 42  IRLIVTDVDGTLLDSSQQLSPRVEAAVKEARAHGVPLVIATGKARGP-WTADVLLGLQLD 100

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
           +  +   G  V+D  G ++    L  D+A D   +  D   +    Y  D          
Sbjct: 101 TPGVFMQGLIVYDDQGRVLHERRLCEDVARDCITLAAD-VGVTLTAYCGDRILCAATDVH 159

Query: 120 EMR--FFKEAVFQYALYEPGLLEPEGV--SKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             R  F+KE   +        L   GV   K+ F  D  +++  L  A  A    R +++
Sbjct: 160 TDRLLFYKEPPPEPVGDLAAALGGGGVPVHKMIFMAD-QDRIDALRPAAEALLDGRASLT 218

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            +    LEV+  G SKG  L  +   LG + +  +A GDG ND EML +AG G  MG+A 
Sbjct: 219 TALTGMLEVLPLGGSKGAGLSWLLDWLGVAPEQVLALGDGENDVEMLQLAGLGVAMGNAG 278

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            + +     + +  TN  D V   +++  L
Sbjct: 279 PKARAAAD-VVLAATNDQDGVAEAIQRFVL 307


>UniRef50_A0M3X3 Haloacid dehalogenase-like hydrolase n=2 Tax=Flavobacteriaceae
           RepID=A0M3X3_GRAFK
          Length = 269

 Score =  227 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 60/272 (22%), Positives = 128/272 (47%), Gaps = 13/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M++++ SD+DGTLL+ +  LS Y  ET++ L+   I F+  + R    +  ++  ++I+ 
Sbjct: 1   MFKIIFSDIDGTLLNAERDLSEYTIETIRKLSKADIPFILISSRMPAAMRHLQKKMDIEH 60

Query: 61  -YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
             +I+ NG  +  +DG ++ +  +  +I ++L    N++ ++  +++ +DEW++ R    
Sbjct: 61  LPIISYNGGLII-VDGKVVSSTEIPIEILTELHKF-NEHQNVHLSLFHNDEWYVPRDDFW 118

Query: 120 EMRFFKEAVFQYA------LYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
             R       Q        +      E +G  K+    +  E++  +   +   + D ++
Sbjct: 119 TQREINNTRVQPEFESNQNVINKWRKESKGAHKIMAMGE-EEKIDAIMTFLLQNFKDELH 177

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAK-KLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           +  S  T +E+    +SK  A++ +        L   +AFGD  ND EM+   G G  +G
Sbjct: 178 LYRSKPTYIEIAPKAISKLTAVQHLLDNHFRIPLSQSMAFGDNYNDVEMIRGVGMGIAVG 237

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A   + ++   +   G   +D V   + +L 
Sbjct: 238 NAKPEVLEIAHMVTTPG--KEDGVAKSIMELL 267


>UniRef50_Q8RF49 Hydrolase (HAD superfamily) n=10 Tax=Fusobacterium
           RepID=Q8RF49_FUSNN
          Length = 270

 Score =  227 bits (581), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 62/263 (23%), Positives = 121/263 (46%), Gaps = 3/263 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V SDLDGTLL+ D  +S    E +K L   GI F  ATGR      +IR  + ++ Y+
Sbjct: 8   KLVVSDLDGTLLNDDSEVSNETIEMIKKLKENGIEFAIATGRSFNSANKIRKEIGLEIYL 67

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFMNRHRPEEM 121
           I +NGA +++ +G +I  + +  D+   +   + +N             +++      + 
Sbjct: 68  ICNNGANIYNKNGKMIKNNIMPADLIRKVINFLTENSIGYFAFDGSGINFYVPNDIEIDA 127

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
               E +  Y      +     + K+    +  E++  ++  ++  + + + +  S   C
Sbjct: 128 ELLNEHIPHYIKNLEDINNLPALEKILIIEEDTERIYEIKDLVHKNFDNELEIVISADDC 187

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           L++   G SK   +E ++++L  + K+ +AFGD  ND +ML   G    M  +    +D 
Sbjct: 188 LDLNIKGCSKRGGVEYISQELKINPKEIMAFGDSGNDYKMLKFVGHPVAMKDSFMSKRDF 247

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
             + +   TN +  V  YL+K +
Sbjct: 248 ENKTDF--TNDESGVAKYLQKYF 268


>UniRef50_C1I4C1 HAD superfamily hydrolase n=1 Tax=Clostridium sp. 7_2_43FAA
           RepID=C1I4C1_9CLOT
          Length = 278

 Score =  227 bits (580), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 60/279 (21%), Positives = 125/279 (44%), Gaps = 21/279 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V  D+DGTLL     +S  +K+ +K +  +G+  V  TGR + +       L ++S 
Sbjct: 3   YKMVCIDMDGTLLGKGKEISKESKKIIKEIHEKGVEIVVTTGRIYNNAAYYSHLLGVESP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE- 119
           +I +NGA V + +   +I+   ++ +    L   +     +  + Y  D  + +    E 
Sbjct: 63  VIAANGAIVREKNTNKVIYEKPIETEECIKLVEKLYKMK-MHFHFYTLDSIYCSNKLTEL 121

Query: 120 -------------EMRFFKEAVFQYALYEPGLLEPEG-VSKVFFTCDSHEQLLPLEQAIN 165
                         ++     +     ++    +  G ++K        E++L +++ ++
Sbjct: 122 GTKLYMTKQIGYDNLKINYYVINNIEKWKDFFRKNHGKITKCIAFSMKPEKILKVKKQLD 181

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
              G  +    S    +E+ + G SKG+A++A+A   G+  ++ +  GD  ND  M+  A
Sbjct: 182 TFEG--IVYYGSGKRSVEINSKGASKGNAVKALANYYGFKREEIMCIGDNENDLSMIEYA 239

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G G  MG+A + +K L     +  TN ++ V   ++K +
Sbjct: 240 GVGVAMGNAIEPVKKLAD--YITDTNIENGVEKAIKKFF 276


>UniRef50_B7GIB3 Predicted hydrolase of the HAD superfamily n=3 Tax=Bacillales
           RepID=B7GIB3_ANOFW
          Length = 258

 Score =  227 bits (580), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 67/263 (25%), Positives = 108/263 (41%), Gaps = 10/263 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V  D+DGTLL  D  L     E +  L  +G+    ATGR       +R  L+I S+ 
Sbjct: 4   KIVFFDIDGTLLDHDKQLPESTYEAIHELKKQGVYVAIATGRAPFMFEALRKELDIPSF- 62

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ++ NG  V   +G +I+   LDR     L  +  DN   +  +  D         P    
Sbjct: 63  VSFNGQYVV-FEGEVIYNQPLDRKQLRALKQMARDNDHPLIFMDADTMRASVPDHPYIHE 121

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
                 F +  ++    E   + +    C   E+  P  Q+       R +   +     
Sbjct: 122 SMGSLKFTHPPHDETYDERNDIYQALLFCKPEEE-QPYIQSFPTFHFVRWHAVST----- 175

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +V+  G SK   ++ +  +LG   ++  AFGDG+ND EML   G G  MG+ H+  K + 
Sbjct: 176 DVLPYGGSKAEGIKKMMNELGIPRENVYAFGDGLNDTEMLRFVGTGVAMGNGHEEAKKVA 235

Query: 243 PELEVIGTNADDAVPHYLRKLYL 265
               +     +D +   LR L L
Sbjct: 236 D--FITKPVDEDGILFGLRHLGL 256


>UniRef50_D1AWH0 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepID=D1AWH0_STRM9
          Length = 269

 Score =  227 bits (580), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 91/269 (33%), Positives = 143/269 (53%), Gaps = 7/269 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V +DLDGTLL+  H +S Y+K+ +K    +G  F  ATGR H    +I D++ +K 
Sbjct: 1   MYKAVVTDLDGTLLNSSHKVSEYSKKVIKKFVEKGYKFYIATGRLHASTKEIADSIGVKI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDL--FGVVNDNPDIITNVYRDDEWFMNRHRP 118
            +IT NG R+ D +GN I+ + L  +    +      +   D++ N Y  + W +   + 
Sbjct: 61  PLITVNGTRILDENGNEIYNNTLSFETVKKIASLDYKSCGEDLLINGYFRNVWLVTDKKA 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVF---FTCDSHEQLLPLEQAINARWGDRVNVS 175
           EE  ++++       +   + E E +SK F       +HE LL L + I     + +NV 
Sbjct: 121 EE--YYRKERPDKPYFPNTVSEEEFMSKTFNKMHFIGNHESLLKLREKILKEIDEDLNVV 178

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
           F   TCLE+     +K  A + V +K G  L + IAFGD +ND EML   GKG +MG+A 
Sbjct: 179 FVGNTCLEIFNKDANKAKAAKFVLEKDGIKLSEAIAFGDSLNDYEMLKEVGKGFLMGNAI 238

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             LK++ PELE+I TN +D     + +++
Sbjct: 239 YLLKEMAPELEIIETNDNDGEAKKIEEIF 267


>UniRef50_C9LXL4 HAD hydrolase, IIB family n=1 Tax=Selenomonas sputigena ATCC 35185
           RepID=C9LXL4_9FIRM
          Length = 265

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 65/267 (24%), Positives = 116/267 (43%), Gaps = 7/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  DLDGTLL+ +  +S Y+K+ L+    +G+    ATGR  +        +   + 
Sbjct: 3   IRLIVMDLDGTLLTSEKMVSDYSKDVLRRAMEKGVAVTLATGRMLLSASYFGRIIGANAP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I+ NGA V  LD    +F      +  ++L     +N       Y  D+ +    RPE 
Sbjct: 63  IISCNGALVQALDATEPLFLRAFSPETVAELLTFAREN-GWYAQWYIGDDIYAEDFRPEY 121

Query: 121 MRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
              ++  +    + + E      EGV++V    D    +  +  +I  R+  RV+   S 
Sbjct: 122 FTAYRTVQGFAVHEVGEDFSPYVEGVAQVVVR-DLAGGVGAIAASIRERFAGRVDPQQSK 180

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              L+++  GVSK   +EA+ +  G    + +A GD  ND  ML +AG   +  +  +  
Sbjct: 181 GYTLDLVPTGVSKATGIEAILRATGIRADEVMACGDSDNDLSMLRLAGTSVVTANGQEEA 240

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K L     +     +D V   + +L L
Sbjct: 241 KALA--TYLAPGCDEDGVARAIEELVL 265


>UniRef50_A9BES4 Cof-like hydrolase n=1 Tax=Petrotoga mobilis SJ95
           RepID=A9BES4_PETMO
          Length = 277

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 120/272 (44%), Gaps = 12/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDN----L 56
           M +    DLDGTLL+ +  +SP   + LK L   G   + A+GR +     + +N    L
Sbjct: 1   MKKTFVFDLDGTLLNSEVRISPKTYQALKRLKEEGHIIIIASGRMYASTMYVVENFLPFL 60

Query: 57  EIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           +    + + NG  + D +G ++F   +  + A      + D  +I  ++Y +D+      
Sbjct: 61  KGNVIISSYNGGYIVDHNGKVVFEKGVANESAIKCIKFLRD-LNIHRHIYINDKLISEID 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPE----GVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
             E   + K +   Y L +  + E E       K+    +  +++  +++          
Sbjct: 120 DKEIRDYSKHSFVDYVLVDDLIAEIETSSHPTLKILAIGEP-DKIDVIKKLAENELQGEF 178

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           N+  S  T L+ +  GVSKG++L+ ++K           FGD  ND +ML +      MG
Sbjct: 179 NLMKSWDTYLDFIPYGVSKGNSLKIISKIYNLDPNTLYVFGDSENDIDMLELTKNSFAMG 238

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A + +K +     ++ +N +D V + + K+ 
Sbjct: 239 NAKEDVKKVAN--YLLPSNDEDGVAYAIEKIL 268


>UniRef50_C8RSV0 HAD family hydrolase n=2 Tax=Corynebacterium jeikeium
           RepID=C8RSV0_CORJE
          Length = 272

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 71/268 (26%), Positives = 119/268 (44%), Gaps = 9/268 (3%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +V SD+DGTLL+    +S   +  +  +  +G  F  ATGR    +  + + L ++    
Sbjct: 7   LVVSDVDGTLLNSRERVSQRMRRAVSSMLRQGTVFTIATGRPPRWLMPVFEQLPVRPVCA 66

Query: 64  TSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDN-PDIITNVYRDDEWFMNRHRPEEM 121
            +NGA ++D D   ++ A  L+ D+   L   ++++ P +   V R      +R      
Sbjct: 67  CANGAIIYDADRDQIVHAATLEPDLIRALIEQLSESVPGVGFAVERAGTSAFDRADELFS 126

Query: 122 ----RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
                       ++A+     L  + V K+     +                 +   ++S
Sbjct: 127 VSPGYDHAWDSTEHAVQSLEELAAKPVVKLLVRDPNRTSAELFAAVRPFIDATQAKATYS 186

Query: 178 TLTCL-EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
               L EV A G+SK  ALE +A+++G      IAFGD  ND EML+ AG G  MG+A +
Sbjct: 187 YEGGLVEVSAAGISKRSALEWIAEQVGVDAAQTIAFGDMPNDTEMLTWAGHGVAMGNAEE 246

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            LK++    EV  TN +D V   L + +
Sbjct: 247 SLKEVAD--EVTLTNDEDGVAAVLERWF 272


>UniRef50_D0BK11 Cof family protein n=2 Tax=Granulicatella RepID=D0BK11_9LACT
          Length = 278

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 64/270 (23%), Positives = 111/270 (41%), Gaps = 9/270 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL---E 57
           M +V+A DLDGTLL+ D  ++P  K+ ++L   +G+  V  TGR  + +  + + L    
Sbjct: 1   MIKVIALDLDGTLLTDDKKVTPENKKAIQLAKEQGVKIVLCTGRPLMSIYHLLEELELLG 60

Query: 58  IKSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVND--NPDIITNVYRDDEWFMN 114
              + I  NG  +       ++F     RD     +        P ++ ++ R  E    
Sbjct: 61  DDDFSINYNGGIIQKTKSQEILFKQGHSRDDMQYCYEEAYKVGLPLVMIDLERAYETTYP 120

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
             RP         + ++    P   E   V      C     L    + +   + ++ N 
Sbjct: 121 EGRPSIYPGLPHPI-EFITKNPSEFEESHVFYKAVLCIEESLLDKGIRQLPEAFFEKFNC 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LEV+   VSKG  L  +A+ LG ++++  A GD  ND  ML+  G    MG+ 
Sbjct: 180 MKSRTFLLEVVPKEVSKGTGLTHLAEILGITVEEIAACGDEENDLSMLTTVGFPVAMGNG 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
              +K++     +  TN +  V H +  + 
Sbjct: 240 SPEVKEVAK--FITKTNEESGVAHAIYHIL 267


>UniRef50_B2GFE5 Hydrolase n=12 Tax=Lactobacillus RepID=B2GFE5_LACF3
          Length = 273

 Score =  227 bits (579), Expect = 4e-58,   Method: Composition-based stats.
 Identities = 65/274 (23%), Positives = 112/274 (40%), Gaps = 12/274 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++A D+DGTL++    ++   KETL+  TA+GI  V  TGR    V +  D L I   
Sbjct: 3   IKLIAIDIDGTLINDQLEITEKTKETLQKATAQGIKVVLCTGRPMTGVHKYLDQLGINNL 62

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y+I+ NGA      G +I    L  +   DL   V    D+       D  ++    
Sbjct: 63  ADQYVISFNGALAQTTSGQVISQFTLPFEKLVDL-SAVALKADVHLLAETADAMYVLNQD 121

Query: 118 PEEMRFFKEAVFQYAL-----YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
                 ++ ++    +      +   ++ + V       D    +      + A      
Sbjct: 122 ISSYAVYESSLVSLPITYKSIDQLNTIKNDLVISKLMITDEPAAIDGFSAKLTAPIKRAF 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           N+  S    LE +    SKG AL ++ ++LG +  + +A G+  ND  M++ AG G  M 
Sbjct: 182 NIVRSEPYYLEFVNPSASKGAALASLGQELGVARTEMMAIGNAQNDESMITYAGIGVAMS 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           ++      L    E++  N  D V   + K  L+
Sbjct: 242 NSIPSTIQLAD--ELVADNNHDGVAEAVEKFALA 273


>UniRef50_C6VK79 HAD superfamily hydrolase n=17 Tax=Lactobacillus RepID=C6VK79_LACPJ
          Length = 271

 Score =  226 bits (578), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 107/271 (39%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++A D+D TLL     L P     +K    +GI  V  TGR         D L +   
Sbjct: 3   IKLIAIDIDDTLLDSKGQLLPSTIAAVKEAHDQGIKVVLCTGRPLAGAQHYLDALGLAGD 62

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             Y+IT NGA +  + G ++  H +D      L      +      +  D   +      
Sbjct: 63  DQYVITYNGAVIESIAGRIVAKHLVDNAHYRQLTAFGKQHHVPFNVLDADSTIYTADRDV 122

Query: 119 EEMRFFK--EAVFQYALYEPGLLEPE-GVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             +   +  E      + +P  L  +  ++K  F  +   QL  +E  +   +G  + V 
Sbjct: 123 NWVTVVQAWENKAGLLIRDPDDLPADFQIAKGVFVGEGP-QLDAVEAQVKTTFGRDLYVV 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            +    LE+M  GV+KG A++ +A  L     + +A GD  ND  M + AG    MG+  
Sbjct: 182 RAATNFLELMHIGVNKGQAVQDLAAALEIQPDEVMALGDEQNDLPMFAFAGTAVAMGNGS 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              K       V  TN  + V   +R+  LS
Sbjct: 242 DIAKAHADH--VTATNDANGVAAAIRQWALS 270


>UniRef50_B0N4M8 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B0N4M8_9FIRM
          Length = 272

 Score =  226 bits (578), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 69/268 (25%), Positives = 118/268 (44%), Gaps = 10/268 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++A DLDGTL S D  + P  K  L+ L  RG+  V A+GR    +    + LE+   
Sbjct: 3   YKLIALDLDGTLKSTDKQILPKTKAILQELAKRGVVIVLASGRPTAGLYAEANELELDKT 62

Query: 60  -SYMITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NGA+V D     +I+    D   A  ++       ++    Y D+        
Sbjct: 63  GGYLLSFNGAKVVDYKTKEIIYQKVYDAKTAHQVYERAKQY-NLAVMTYTDELILTEDET 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
            E +    +       +     +     V+KV  T    E    +     A +GD +++ 
Sbjct: 122 DEYVCIEGDINHMPIKHIDNFKDAVNFSVNKVLLTAKP-EYAETILDEFKAPYGDSLSIY 180

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    +EVMA G+ K  +L+A+ ++LG    + I+FGDG ND  M+  A  G  M +A 
Sbjct: 181 RSAPFFIEVMAQGIDKAASLQALIERLGIKRDEVISFGDGYNDLSMIEFAKFGVAMANAV 240

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKL 263
             +K       +  +N ++ +   L+ L
Sbjct: 241 DEVKKRAA--YITLSNDEEGIYECLKML 266


>UniRef50_B2IW20 Cof-like hydrolase n=18 Tax=Cyanobacteria RepID=B2IW20_NOSP7
          Length = 289

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 57/272 (20%), Positives = 116/272 (42%), Gaps = 11/272 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGT+    +T+S   K+ +    A+GI    ATGR +    +   ++     
Sbjct: 21  IKLLVLDIDGTIAGHSNTISAGVKQAIVAAQAQGIPVAIATGRMYRSALRFHQDIGSTLP 80

Query: 62  MITSNGARVHDLDGNLIFAH-NLDRDIASDLFGVVNDNPD----IITNVYRDDEWFMNRH 116
           ++   GA + D +   I  H  + R++A  L     + P+    +  + Y +D+ ++   
Sbjct: 81  LMAYQGAWIQDPNTQQIHRHWAISREMAHQLLDYF-EQPELRSLLSVHFYINDQLYVREL 139

Query: 117 RPEEMRFFKE-AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARW-GDRVNV 174
             E   + +  A+    + +         +K+    D  + +  L   +  ++    + +
Sbjct: 140 TRETQIYAERSAIIPIPVGDLRQTLTNEPTKILALSDDTDLIDRLLGNLRRQYTPAELYL 199

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVA-KKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           + S  T  E     V+KG A+  +A + LG  + + +A GD  ND EML   G G  MG+
Sbjct: 200 TTSVATFFEATNASVNKGTAVRYLAEELLGLEIANVMAIGDNFNDVEMLESVGLGVAMGN 259

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A + ++ +     V  +  +D     + K  L
Sbjct: 260 APEGVQAIAQW--VAPSVEEDGAAVAIEKFLL 289


>UniRef50_Q1WSZ0 Hydrolase, HAD superfamily n=9 Tax=Lactobacillales
           RepID=Q1WSZ0_LACS1
          Length = 291

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 66/290 (22%), Positives = 121/290 (41%), Gaps = 31/290 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M Q++ASD+DGTLL+    +S    + +K     G++F+ ++GR + ++  + +  +  S
Sbjct: 1   MIQIIASDMDGTLLNDKMVISKRNADAIKEAQKNGVHFIVSSGRGYNEIKPLIEAADFNS 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            MIT NGA V D +G ++ +  L +  A  +  ++     +   V      + +      
Sbjct: 61  PMITLNGAEVLDENGKVLSSSPLPKITAKKIIRLLRKK-GLYAEVITSKGIYSDNKAKRI 119

Query: 121 MRF------------FKEAV-------------FQYALYEPGLLEPEGVSKVF-FTCDSH 154
             F            +K AV             +     E    +   V K+  F+ +  
Sbjct: 120 ENFAELLTRVSPDTPYKLAVIMASNRLELMNINYTDDYMELIDEKHTKVFKIVAFSSEGK 179

Query: 155 EQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGD 214
           + L P+   I+      + V+ S+ + +E+      KG AL+A A  L   + + +A GD
Sbjct: 180 KVLDPIRDEISQ--NSELVVTSSSESNIEINHVNAQKGIALQAYADYLNIPMDNVMAIGD 237

Query: 215 GMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             ND  ML +AG    M +    +K L     +  TN  D V   + ++ 
Sbjct: 238 NNNDVSMLKVAGMSYAMENGSNEVKMLAKR--IADTNTSDGVGKAIEEVL 285


>UniRef50_C0ZHG1 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZHG1_BREBN
          Length = 289

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 67/282 (23%), Positives = 117/282 (41%), Gaps = 24/282 (8%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +VA D+DGTLL+ D  L+   KE L+ L  +G   V +TGR +       D+     Y +
Sbjct: 7   MVAFDMDGTLLTHDSKLTEGTKEALRQLQQQGCKLVLSTGRMYGSAQIPIDSFPFDGY-V 65

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII-TNVYRDDEWFMNRHRPEEMR 122
            SNG  V + DG L+    L  ++       +         +    + W +   R     
Sbjct: 66  CSNGGTVFEGDGTLVRQWLLPTEMVIGAIHALRQETIYYELHDTNSNRWMIKEDRERLEA 125

Query: 123 FFKE-------AVFQYALYEPGLLEPEG------------VSKVFFTCDSHEQLLPLEQA 163
              E       ++  +  Y    +EP              + K F      ++L  +++ 
Sbjct: 126 TMSEDASVEGFSILSFPYYRLARVEPLAEVLEKVESGEVEIVKFFVWHQDPDRLEWVKEQ 185

Query: 164 INARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLS 223
           +   W ++V ++ S    +EV+  GVSK   L+   +K G S +  +AFGD  ND E L+
Sbjct: 186 LKP-WSEQVTITSSGKQNVEVIPQGVSKWEGLQYFCEKWGISPEKVMAFGDAENDREALT 244

Query: 224 MAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            AG    M +A   +K +     +   + ++ V  ++R+  L
Sbjct: 245 GAGYSVAMENASDEIKQVAK--YIAPHHNEEGVARFIRERVL 284


>UniRef50_Q034C6 Predicted hydrolase of the HAD superfamily n=8 Tax=Lactobacillus
           RepID=Q034C6_LACC3
          Length = 273

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 65/277 (23%), Positives = 112/277 (40%), Gaps = 26/277 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M + +A D+D TLL+    +S   ++ L+ L+ +GI  +  +GR    +    D L +  
Sbjct: 1   MLKAIALDMDNTLLNSQKEISVTNQDVLRYLSRKGIRVILCSGRPFATLKPFLDQLHLTK 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF---- 112
                I  NG  V  + D  +I +  L +     ++ +V +      +V  +D+ +    
Sbjct: 61  NDDVCICFNGGLVRLVRDHTVIKSSTLTKSQIQPVYDLVKEK-GFHLDVVAEDQVYSLTE 119

Query: 113 -----MNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
                     P++M F      +             + KV    D  E +    +A  + 
Sbjct: 120 FGKSSYESMIPKQMPFTDTTFAKVPA-------KLSIFKVVIAGDP-EMVDAASEAAQSL 171

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
            G  V V+ S  T LE+M   V+K + L+A         +   AFGD  ND +ML  AG 
Sbjct: 172 EG--VTVTRSRRTLLEIMPPNVNKKNGLKAALNFYRIPREQLAAFGDEENDQDMLDYAGI 229

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G  MG+A   +K +        +N +D V  +L   +
Sbjct: 230 GIAMGNAIPEIKKIAD--ITTQSNDEDGVAKFLIDYF 264


>UniRef50_C4V675 HAD superfamily hydrolase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V675_9FIRM
          Length = 278

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 60/264 (22%), Positives = 104/264 (39%), Gaps = 3/264 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++  SDLDGT+L     +S      ++     G+    ATGR       + + L +   +
Sbjct: 4   KLFVSDLDGTMLPSGDIVSSENIAAVQCAVRAGVTVTIATGRMFEAALPVAEALGVDVPI 63

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I  NGA +    G +   H +D  +A D+          I +       +          
Sbjct: 64  IAYNGALIKSPSGRIYEEHAIDPMLARDIITFAQARGWYIQSYSGGVLRYAIACEESRFY 123

Query: 123 FFKEAVFQYALYEPGLLE-PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
              + +   A+   G+L    G  K+    +         Q +   +G  + V+ S    
Sbjct: 124 ENSQKITGKAVGRNGMLAYVTGNCKLLLVTEGRAVSEARAQMLMDAFGAHIGVTRSADRL 183

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +E++  GVSK  AL A+A KLG +  + +A GD  ND  ML  AGK   MG+A   +K+ 
Sbjct: 184 VEIVVKGVSKASALTALAAKLGITADETMAIGDAYNDLPMLKAAGKSVAMGNAFPEVKEE 243

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                +  +  ++ +   +    L
Sbjct: 244 ADYETL--SCTENGLAAAIYTYVL 265


>UniRef50_Q0TU23 HAD-superfamily hydrolase, subfamily IIB n=7 Tax=Clostridium
           perfringens RepID=Q0TU23_CLOP1
          Length = 274

 Score =  226 bits (577), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 65/276 (23%), Positives = 116/276 (42%), Gaps = 16/276 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGTLL     ++   K  +K    +G      TGR +       D + +K+ 
Sbjct: 3   IKLICIDMDGTLLMDQQNIAEEDKNAIKEAVKKGAIVAITTGRIYDCARMYSDTIGLKTP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I SNGA +  ++   I+ + L +    D F ++    ++ T V  +         PE  
Sbjct: 63  IIASNGAYIGGVNDEEIYNNPLKQSDLED-FNIITKKNNLFTYVTTNWGIVSTVELPENH 121

Query: 122 RFF-------KEAVFQYALYEP-----GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
            +        K+   +  + +         + E +  V    +  ++L   ++ + A   
Sbjct: 122 VYKVLNKTLPKDKQVRLEVVKDLDEAFKKYKGEILKGVCVEKEFKDKLKEAKEELIACTT 181

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           D + V  S     E+M  G SKG A++ +AK LG S ++ +  GD  ND  M++ AG G 
Sbjct: 182 D-LEVVSSWDDNFEIMKKGSSKGEAVQMLAKYLGVSQEEVMCIGDSENDLSMITWAGTGV 240

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            MG+A   +K+      V   N    V   +RK  L
Sbjct: 241 AMGNAIDSVKEFAN--YVTSDNKHGGVAEAIRKFVL 274


>UniRef50_Q819K1 Hydrolase (HAD superfamily) n=77 Tax=Bacillaceae RepID=Q819K1_BACCR
          Length = 257

 Score =  226 bits (577), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 66/259 (25%), Positives = 111/259 (42%), Gaps = 10/259 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V  D+DGTLL  D  +    ++ +K L  +G++   ATGR       IR  L+I +Y 
Sbjct: 4   KIVFFDIDGTLLDHDKKIPQSTRDAVKQLQEKGVHVAIATGRAPFMFEDIRKELDIHNY- 62

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ++ NG  V   +  +IF + L  D               +  +   D      +      
Sbjct: 63  VSFNGQYVV-FEDEVIFNNPLHPDALHKFTQFAKQEGYPLVYLDHQDMRASVEYHDYVKE 121

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
            F    F++  YEP   E   + +    C+ +E     E+     + D  +        +
Sbjct: 122 GFGSLNFEHPAYEPNFYEERNIYQTLLFCEVNE-----EEKFINHYPD-FHFIRWHAYSM 175

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +++  G SK   +E   +KLG++     AFGDG+ND EM+   G G +MG+ H+ LK L 
Sbjct: 176 DIIPNGGSKAKGIEKYIEKLGFNRDQVYAFGDGLNDLEMIEAVGTGIVMGNGHEDLKKLA 235

Query: 243 PELEVIGTNADDAVPHYLR 261
               V     +D + H L+
Sbjct: 236 NH--VTKDVNEDGIYHGLK 252


>UniRef50_C7RDZ8 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7RDZ8_ANAPD
          Length = 267

 Score =  226 bits (577), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 65/270 (24%), Positives = 116/270 (42%), Gaps = 8/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDN---LE 57
           M ++VASD+D TL+  D  +    +  ++    +GI  + ATGR   ++  I      + 
Sbjct: 1   MIKLVASDIDETLVDNDKNVPERNRIAIQKAQEKGIIVMLATGRGTYELFDIPKQAGVIH 60

Query: 58  IKSYMITSNGARVHDLDGNLI-FAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I  NGA + ++    I  +  L  + A  +F     N         D ++ +N  
Sbjct: 61  DDRYVICCNGAIIMNVKTKEIVHSMGLKYEYAKTIFDYAYANNQTCYIYTLDHKYGLNLD 120

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
           R     + +E + +        ++ + + K          L  LE  I       V +++
Sbjct: 121 RD---SYAEEQITELTDNNIDFIKDQIILKAILKNKDMNYLQGLEIDIAYLTNYDVEIAY 177

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S+   +E+ A GV+K  ALE V +  G  L + +A GD  ND  ML  AG    + +AH 
Sbjct: 178 SSDMFMEINAKGVNKARALEKVCEHYGIGLDEVLAIGDNYNDVAMLGEAGTSVAVANAHL 237

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           ++K+    +    TN + AV   + +  L+
Sbjct: 238 QVKESANFVA-EATNEEGAVGEAIERFVLN 266


>UniRef50_C1QEL1 HAD-superfamily hydrolase, subfamily IIB n=3 Tax=Brachyspira
           RepID=C1QEL1_9SPIR
          Length = 266

 Score =  225 bits (576), Expect = 8e-58,   Method: Composition-based stats.
 Identities = 65/264 (24%), Positives = 126/264 (47%), Gaps = 7/264 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLT-ARGINFVFATGRHHVDVGQIRDNLEIKS 60
            +++A+DLDGTLL+ +  +S Y ++ +K L     I+F+ ++GR    +      LE  +
Sbjct: 8   IKLIAADLDGTLLNSNKEISKYNQKIIKKLINEYNIDFILSSGRPFEGIKNYNKLLENNN 67

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             I  NGA + D +G +IF   ++ + +  +  +     D+  +VY + ++ +++     
Sbjct: 68  LSIIFNGASIADNNGKIIFQQTIEEESSKQIIELSKKY-DVCMHVYNNGKYIISKENFPI 126

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             + +       +      +     K+       + L  L++ I++   + V+  FS   
Sbjct: 127 KSYVQIEKTVNVIVGLENTDDYNFDKILILG-QRDILEKLKKEIDSL--NCVHTCFSGDL 183

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE +    +KG+AL+ + +     +KD IAFGD  ND EM+  AG G  MG+A + +K 
Sbjct: 184 FLEAVNKASNKGNALKRICEIKKIDIKDTIAFGDNFNDIEMIKYAGIGVAMGNAEEIVKQ 243

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                 +  +N +D V  +L  L+
Sbjct: 244 EA--YYITLSNEEDGVGKFLSDLF 265


>UniRef50_Q5FQA0 Putative hydrolase of the HAD superfamily n=1 Tax=Gluconobacter
           oxydans RepID=Q5FQA0_GLUOX
          Length = 266

 Score =  225 bits (576), Expect = 8e-58,   Method: Composition-based stats.
 Identities = 67/263 (25%), Positives = 107/263 (40%), Gaps = 4/263 (1%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +V SD+DGTLL+PD T++P     +++L  RGI    A+ R    +    + L +     
Sbjct: 1   MVVSDMDGTLLTPDKTIAPSTLAMVRVLQERGIPLCLASARPPAAMVPYIEQLGLTGQNA 60

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRF 123
             NG  +   DG    +  L  D+ S +  +++ +  I T   R   W +       ++ 
Sbjct: 61  GFNGGIIFKPDGTTSVSRVLSPDVLSIVHDMLHLH-GIETWFLRQSYWMVQDAYTPFVQH 119

Query: 124 FKEAVFQYALYEPGL-LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
            +          P L  E EG+ KV         L  +E  + A      +V  S+   L
Sbjct: 120 EQGITGLTPHQVPDLRKEFEGIGKVMGVSSDTSLLQDVETELGAMLQGDASVRRSSDILL 179

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +V     +KG A+  +A  LG +  +    GD  ND  M S+AG G  MG A   +K   
Sbjct: 180 DVTPALANKGEAVRELALALGIAPHEVACLGDAHNDLPMFSVAGLGIAMGQAEDDVK--A 237

Query: 243 PELEVIGTNADDAVPHYLRKLYL 265
               +  TN  D     + +  L
Sbjct: 238 AAQVLTDTNERDGWAKAVERYIL 260


>UniRef50_C4G5S2 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G5S2_ABIDE
          Length = 266

 Score =  225 bits (576), Expect = 8e-58,   Method: Composition-based stats.
 Identities = 65/264 (24%), Positives = 122/264 (46%), Gaps = 9/264 (3%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +V SD+DGTLL+ +H +       ++ L  + I FV  + R    +  I +       +I
Sbjct: 5   IVFSDVDGTLLNNEHKMLEGTMYAIQKLQEKDIPFVIISARSPSGIYPILEENGFSCPII 64

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFMNRHRPEEMR 122
             +GA + D   N +++   D++ A ++   + +   D   N+Y  D W + + + +   
Sbjct: 65  CYSGALILDDKKNTVYSTGFDKETAENVINFIEEEKFDCCWNLYSGDNWIV-KDKNDPRV 123

Query: 123 FFKEAVFQYALYEPGLL---EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
             +E +      E  L    +   V K+   C + E+ + +E  I  ++   ++V  S  
Sbjct: 124 ICEENIVHTEAVEGTLALLPDNAEVGKILCIC-NPEKTIEIEDKIKKQFP-MLSVVKSFN 181

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           T +E+M  G++KG A+  + K         +AFGD  NDA+ML + G   +MG+A + LK
Sbjct: 182 TMIEIMQTGITKGSAVLELCKLWNIKPDKAVAFGDNFNDADMLDVVGFPFLMGNAPKELK 241

Query: 240 DLHPELEVIGTNADDAVPHYLRKL 263
                  +  +N D+ +   L K+
Sbjct: 242 --LRFKNITDSNNDEGIYKALAKM 263


>UniRef50_A8ST52 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A8ST52_9FIRM
          Length = 277

 Score =  225 bits (575), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 61/269 (22%), Positives = 114/269 (42%), Gaps = 10/269 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK--- 59
           +++A D+DGTL +    ++P   + +  +  +G     A+GR    + +I D +++    
Sbjct: 8   KLLALDIDGTLTNTQKDITPETLKKIIEVQEKGHVVAIASGRPLPGIRKIADIIQLDRFG 67

Query: 60  SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y++  NG R+ +   G +++   LD +I  D++             Y  D         
Sbjct: 68  GYVLAFNGGRIVNYKTGEVVYQAALDNEIVRDIYDYCLK-VGCGMVTYDGDRVITGTDID 126

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGV--SKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             M F         +      E      +K   T +  ++   +E+ + +R+GD+V +  
Sbjct: 127 GYMTFEASINHMELMRIDDFKEYIDFPLNKCLLTAEP-DKAEKIEEELVSRFGDKVTIFR 185

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    +E+M   V K  +LE +   L   ++D IA GDG ND  M+  AG G  M +A  
Sbjct: 186 SEPYFVEIMPQNVHKATSLEKLLGVLNMDVRDLIACGDGYNDLTMIEYAGVGVAMANAQD 245

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +K       +  +N +D +   + K  L
Sbjct: 246 IVKKHAD--YITLSNDEDGLVPVVDKFIL 272


>UniRef50_C1P783 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36D1
           RepID=C1P783_BACCO
          Length = 305

 Score =  225 bits (575), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 69/289 (23%), Positives = 117/289 (40%), Gaps = 29/289 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + +ASD+DGTLL+    +SP   E +KL   +GI+FV  TGR + +   + D + I  
Sbjct: 18  MIECIASDMDGTLLNSRQEVSPANAEAIKLAQKKGIHFVVTTGRSYEEARLVLDPVGIDC 77

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE- 119
            +I  NGA V D  G L+    LD   AS +  V  D   I    + +   +   +    
Sbjct: 78  TVIGLNGAEVRDEKGKLLKTSGLDPLTASQVADVF-DQLGIYYEFFTNKGTYTEDYEENM 136

Query: 120 -----------------------EMRFFKEAVFQYALYEPGLLEPEG-VSKVFFTCDSHE 155
                                  E R  +  V      +    +P     K+    +  +
Sbjct: 137 DMLVNLFHTANPEVPVEEVRNYIEQRGIRRYVHNIRDTKDIFHDPSILFYKILAFNEDEQ 196

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           +L  + + +   + D + V+ S    +E+      KG AL+   +K G S++  +A GD 
Sbjct: 197 RLRQIGKHLEKDFPD-IKVTSSGFRNIEINHVSAQKGIALKEYTEKHGLSMEKTMAIGDN 255

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +ND  ML   G    MG+A   + ++         N +D V   + ++ 
Sbjct: 256 LNDISMLERVGYPFAMGNAENEVLEICRYR--TKRNDEDGVAKAIYRML 302


>UniRef50_UPI0001788F0C Cof-like hydrolase n=1 Tax=Geobacillus sp. Y412MC10
           RepID=UPI0001788F0C
          Length = 254

 Score =  225 bits (574), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 66/264 (25%), Positives = 118/264 (44%), Gaps = 23/264 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLDGTLL+ +  ++   K+ L+    +G+  +F+TGR         D L + S 
Sbjct: 11  YKLIALDLDGTLLTDEKHITDETKKWLQYAVDQGVKVMFSTGRGLQTAKGFWDELGLDSP 70

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           M+  NGA V +  G L     L RD   D+  +               EW+         
Sbjct: 71  MVLLNGAEVWEGPGRLKKRVFLPRDAVRDMHAIAAKRG----------EWY--------W 112

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            +  E++     + P + E +   K     +   +L  +++ + +     + V+ S  T 
Sbjct: 113 GYSVESLTGDKDWTPEMFERD-WMKFGIGSNDQRKLAEIKEELLSW--GTLEVTHSAPTN 169

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +E+   G++K   +  V + LG+S+ D IA GD  NDA++L  AG G  M +  + +K +
Sbjct: 170 MEISVKGITKESGVREVCQTLGFSMSDVIAMGDSDNDAKLLKAAGLGVAMANGEEHIKSI 229

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                +  TN ++ V   +RK   
Sbjct: 230 AD--VITATNNENGVAQAIRKYVF 251


>UniRef50_B9EBT4 Putative uncharacterized protein n=1 Tax=Macrococcus caseolyticus
           JCSC5402 RepID=B9EBT4_MACCJ
          Length = 269

 Score =  224 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 63/268 (23%), Positives = 117/268 (43%), Gaps = 9/268 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++  D+D TLL+  + + P     L      G   V A+GR    +    + L++   
Sbjct: 3   YKLIVLDMDDTLLTSKNEILPSTINALIEAQNNGAMVVLASGRPTGGMIDAAEILQLDTH 62

Query: 60  -SYMITSNGARVHDLDGNLIFAHNLDRDI-ASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
            SY+I+ NGA V  ++   +      + +  S++   +    +I+   Y+D+  +     
Sbjct: 63  QSYIISYNGAVVTRMNDRTVVDATYVQQVHFSEILHFLRK-ENIMALTYKDNTIYYEGQS 121

Query: 118 PEEMRFFKEAVFQYALYE-PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             E    +    +    +    +  E V KV    D  E +  L + +   +G  ++ + 
Sbjct: 122 AYEQVEGELTGLEMIKVDNLQTVITEDVPKVMGVGDI-EHIALLNKQLEGSFGSDIHATT 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE M   VSKG  L+ +A++LG    + IAFGD  ND +ML  AG G  MG+A+ 
Sbjct: 181 SKPFFLEFMHRDVSKGKVLQRLAEQLGIQQSEIIAFGDSNNDKDMLEFAGLGVAMGNAND 240

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +K+      +  ++ +D +   +    
Sbjct: 241 TIKEAAD--VITLSHDEDGIAQIIETYL 266


>UniRef50_Q04BG8 Predicted hydrolase of the HAD superfamily n=13 Tax=Lactobacillus
           RepID=Q04BG8_LACDB
          Length = 294

 Score =  224 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 29/289 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++  DLDGTLL+    +S    + +K     GI F+ A+GR   +   +     I  
Sbjct: 1   MIKLITCDLDGTLLNSSMEISDANVQAIKRAQENGIEFMVASGRAPHESQPMLKEYWIDC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII-----TNVYRDD------ 109
             I  NG  V D  GNLI  + L  + A  +  ++             +VY +D      
Sbjct: 61  SFINLNGGLVFDTAGNLIVKNPLKLETAKKICRLLKKEGFYFELVTSNHVYSEDLSQRIT 120

Query: 110 --EWFMNRHRPEEMRFFKEAVF------------QYALYEPGLLEPEGVSKVFFTCDSHE 155
                M    P  M  FKEAV             Q   YE  + EP          DS  
Sbjct: 121 NVAHLMVELNP--MLTFKEAVLVSASKPAIVSIQQVPSYEDLMDEPGTEVMKILVFDSRG 178

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           Q    +        D+++++ S    +E+ A    KG +L   A   G   ++  A GD 
Sbjct: 179 QYAFTDVIKKIEEIDKLSITSSAADNIEINAASAQKGQSLLDYAAAKGIKREEIAAIGDN 238

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +ND  M+  AG G  MG+A  ++K +     V  +N +D V   + K+ 
Sbjct: 239 LNDESMIQAAGTGVAMGNAVPQIKTIAS--FVTKSNNEDGVAWAIDKII 285


>UniRef50_A7VNH3 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VNH3_9CLOT
          Length = 272

 Score =  224 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 67/270 (24%), Positives = 118/270 (43%), Gaps = 11/270 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
           Y+++A DLDGTL++    ++  AK+ +      G     A+GR    +     +L +   
Sbjct: 3   YRLLALDLDGTLVTSHGGITEAAKQAVWSYIDAGGVVALASGRPTRGLWP-AQDLRLAQK 61

Query: 59  KSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NG ++ +   G  I+  ++ +D+   +  ++ D    +  +   D++ +  H 
Sbjct: 62  GGYLLSYNGGKIVNCKTGAAIYEKDIPQDLVPVIIRMIRDAG--MEAISYQDQYVLLEHV 119

Query: 118 PEEMRFFKEAVFQYALYE-PGLLEPEGVSKV-FFTCDSHEQLLPLEQAINARWGDRVNVS 175
                  + +V +    E P L        V    C + EQ+L LE+      G RV+V 
Sbjct: 120 DRLWFDREASVCRMEYKEVPDLAAYVTFPVVKLMACGAPEQILALEKQAQEAIGSRVDVF 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE +A G+ K   LE + K LG +     AFGD  ND  M+  AG G  M ++ 
Sbjct: 180 RSEDFYLEFVAKGIDKAATLEVLLKHLGLTRDSLAAFGDSYNDIPMIKYAGFGVAMANSI 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +        V  +N +D V H + +  L
Sbjct: 240 PEVLQAADA--VTKSNDEDGVAHAIYRYLL 267


>UniRef50_C7HRV4 Hydrolase (HAD superfamily) n=1 Tax=Anaerococcus vaginalis ATCC
           51170 RepID=C7HRV4_9FIRM
          Length = 272

 Score =  224 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 66/272 (24%), Positives = 121/272 (44%), Gaps = 8/272 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A+D D TLLS D T+     + +K     GI    ATGR    +  I + ++   
Sbjct: 1   MIKLIATDCDETLLSDDKTIHKRNIDAIKKAQEMGIIITTATGRGPYQLFDILEQIDNVK 60

Query: 59  -KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              + I  NG  + D +   ++ A  +D   A ++     +   +   +Y D   ++  +
Sbjct: 61  EDRFSILCNGGIIMDNVTKKVVEASPIDYKKAVEISDYCKE-VGVHFEIYTDKHCYVFVN 119

Query: 117 RPEEMRFFKEAVFQYALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
             E    + + ++++      +  L+ E + KV     +   L+ LE+ I       +++
Sbjct: 120 GNEVEGNYDKNIYKFVQKAKDIKNLDKEIIVKVIIKNSNLNYLMSLEEDIARICNWDISI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           S+S+ T +E+    V+K  ALE +    G  +++ +  GD  ND EML  AG    + +A
Sbjct: 180 SYSSDTFMEINRKNVNKAKALEKLCAHYGIGMENVLTIGDNYNDKEMLEEAGYSAAVQNA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           H  LKD+        TN   AV   + K  L+
Sbjct: 240 HLLLKDISKY-TTKATNNQGAVGEAIEKFVLN 270


>UniRef50_C0CY86 Putative uncharacterized protein n=3 Tax=Clostridium
           RepID=C0CY86_9CLOT
          Length = 265

 Score =  224 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 60/265 (22%), Positives = 120/265 (45%), Gaps = 5/265 (1%)

Query: 1   MYQVVASDLDGTLL-SPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK 59
           M +++ SD+DGTL+      ++P   + +  L  +GI F  A+GR    V    + ++ K
Sbjct: 5   MIKLIVSDVDGTLVEDGSGGVNPELFDVILKLREKGIQFAIASGRPWASVEGAFEPVKKK 64

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            + I +NGA +    G  +F + ++ ++  ++   V  +PD+       D  +M+     
Sbjct: 65  IFYIANNGAYL-GCHGRSLFVNPIEPELVREVIEAVRRHPDLSAIYAGQDGDYMDSENDA 123

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
             R+  E           +L  E    +  +    + +      I   + DR+ ++ +  
Sbjct: 124 LYRWMLEGYKFNIRRVKDVLALEDPC-IKISIYKEQDVEHAAADIREAFQDRMKITLAGE 182

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             ++ MA GV+KG A++ + + L    ++ +AFGD +ND EML  A     + +A + ++
Sbjct: 183 MWMDCMAQGVNKGQAVKRLQESLEIRPEETMAFGDQLNDIEMLQQAYYSFAVANAREEVR 242

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
            L        +N +D V   L++L 
Sbjct: 243 KLA--RFQADSNKNDGVLKVLKQLL 265


>UniRef50_D0Z8V8 Hydrolase, Cof family n=1 Tax=Edwardsiella tarda EIB202
           RepID=D0Z8V8_EDWTE
          Length = 271

 Score =  224 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 82/265 (30%), Positives = 127/265 (47%), Gaps = 5/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V +DLDGTLL+P   LS +    LK L+A GI  VFATGRH  D  +I   LE + +
Sbjct: 8   YKAVVTDLDGTLLNPQGQLSTHTLVILKKLSALGITLVFATGRHPRDAQRIAQALEQRPH 67

Query: 62  MITSNGARVHDLDGNLIF-AHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++  NG+       + I   H + +DI +D+   +     I  + +    W +       
Sbjct: 68  IVGLNGSLTLCQQSDAILCEHVIAQDIIADIMRFIAPY-HIHLSAFDSHGWKLYEVNEMA 126

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             + K + F Y    P  +    ++K+     +   + PLEQ +  ++G  +    +   
Sbjct: 127 NDYVKLSGFSYLQIAPSDIFSLKINKLLLWSTN--DIAPLEQRLQQQFGQYLACYRTFAQ 184

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYS-LKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
            LE+   G+SK  A+ A+  + G    +  IAFGDG ND EML  AG G +M +A   LK
Sbjct: 185 QLEIGPRGISKASAVAALLAEKGIDFQRQAIAFGDGHNDTEMLRQAGLGIVMDNAPCELK 244

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
                L V  +NADD V   L+ ++
Sbjct: 245 MQLGTLPVAQSNADDGVAQMLQHIF 269


>UniRef50_A9VQD5 Cof-like hydrolase n=72 Tax=Bacillus RepID=A9VQD5_BACWK
          Length = 319

 Score =  224 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 65/287 (22%), Positives = 121/287 (42%), Gaps = 29/287 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGTLLS +  +S    + ++     G   +  +GR   D  ++ +  ++   +
Sbjct: 31  KLIALDMDGTLLSSNLEISKENLQAIQTAKEAGHIVMICSGRAKEDALKLLEEYKLSLPV 90

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP------------------DIITN 104
             SNGA V+ +DG +I +  L  D    L  ++                      D +  
Sbjct: 91  GASNGAIVY-VDGKVINSRCLQNDKVYKLAKLLESEGFPYKLYTNKGVYSPYTWQDQVMQ 149

Query: 105 VYRDDEWFMNRHRPEEMRFFKE-----AVFQYALYEPGLLEPE-GVSKVFFTCDSHEQLL 158
            + +++  ++    E  R  ++      +  +   E  +  PE  +SK F    +     
Sbjct: 150 AFEENKHTLDVTLEELERITEKQKKSNLITDFQKIEDVVNNPELEISKFFILTFNAAHRS 209

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
            L Q +       ++V+ S  T +E+M     KG+ L+ +A      ++D +A GD  ND
Sbjct: 210 QLLQTLQE--DTDISVTASAPTNVEIMDKHGHKGNGLQEMAAYFNIPIEDTVAIGDNFND 267

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             ML +AG    MG+A + +K L     V  TN +  V H + +  L
Sbjct: 268 VPMLQVAGLSVAMGNAEEDVKKLCD--VVTLTNNEHGVAHAIEQFVL 312


>UniRef50_C6PUS4 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PUS4_9CLOT
          Length = 276

 Score =  224 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 66/276 (23%), Positives = 123/276 (44%), Gaps = 14/276 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ASD+DGTLL+ D  +S Y    +   T+ G+ FV A+GR    +    + +     
Sbjct: 3   YKIIASDMDGTLLNDDKNISNYNLAMINKATSLGVKFVIASGRVPATLKFYEETIGKNQP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEW---------- 111
           +I +NGA V D + N+I+++ + +     +  ++ ++ D   + Y  + +          
Sbjct: 63  IICANGAIVLDHNKNIIYSNPISKSNLIKIINILREDKDTYYHFYDGNVFCSEQFEYSAK 122

Query: 112 -FMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            F N +R  + ++  E        +  +     + K+    D  + L  L   I+    +
Sbjct: 123 KFYNFNRKVDQKYRMEIRLIKDAKDYIIRSNSNIDKIVVMDDDVKYLEYLRCKIDNL--N 180

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            +  + S +  LE+M  G SKG AL+ +AK     ++ CIA G+  ND  M+  AG G  
Sbjct: 181 EIETTKSEINNLEIMGIGSSKGTALKLLAKYYEIPIEQCIAIGNDENDISMIKAAGVGIS 240

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           M +    LK     +     N +  +   + K  L+
Sbjct: 241 MANGRNSLKQYANYIT-EKNNNNGGIGEIIEKFILN 275


>UniRef50_A6LS28 Cof-like hydrolase n=4 Tax=Bacteria RepID=A6LS28_CLOB8
          Length = 275

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 72/273 (26%), Positives = 121/273 (44%), Gaps = 11/273 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTAR-GINFVFATGRHHVDVGQIRDNLEIKS 60
           Y+++A D+D TLL+ +H +     + +K      G+ FV ATGR +  +      L++  
Sbjct: 3   YKLIACDMDETLLNDNHIICQRNIDLIKRAKKEYGVKFVPATGRGYSSIQNDLKILDLYD 62

Query: 61  ----YMITSNG-ARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I+ NG A   + D  L+    L  D   ++F     N D+  +VY  D+ ++  
Sbjct: 63  QAGEYIISFNGGALTENKDNKLLQFKGLRFDKMKEIFEY-GLNKDVCIHVYTKDKLYIYN 121

Query: 116 HRPEEMRFFKEAVFQYALYEP---GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
               E    K    +  + +     LLE E ++K+ +   +   L+ +E  + +      
Sbjct: 122 LSQSEKERIKNQKLECTIMKENTVDLLEEEPIAKIIYQNINVPYLMGIEPDMRSITEGHC 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            VS+S+   +E  + GV KG  L  +AK L   +KD IA GD  ND  ML +AG     G
Sbjct: 182 AVSYSSNRYMEFNSLGVDKGSGLINLAKILDIDIKDTIAVGDNYNDMSMLKVAGLSVASG 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +A + +K           N +  V   + K  L
Sbjct: 242 NAVEDVKRACDY-TTEADNNEGVVAELIEKFIL 273


>UniRef50_Q7MFQ8 Predicted hydrolase n=24 Tax=Vibrionales RepID=Q7MFQ8_VIBVY
          Length = 267

 Score =  224 bits (572), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 61/265 (23%), Positives = 108/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + +A+D+DGTLL P   L+P      + L  +GI F  A+GR +  + +    +  +  
Sbjct: 6   IKFIAADMDGTLLDPSGKLAPEFFHIYQTLEDKGIIFAAASGRQYYSLRETFAPINDRMM 65

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            I  NG  V    G  +++  L      D+  +          +      ++    PE +
Sbjct: 66  FIAENGTLVMH-QGKELYSCGLASTDIKDIIQLTRTIDGAHIVLCGKKSAYVETKHPEAI 124

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
               +   +   Y P LL+ +        C        L  + + R+     V  S    
Sbjct: 125 EEISKYYHRCQ-YVPDLLDVDEAFIKVAICHFEGSQEKLHTSFSERFDATHQVVVSAKIW 183

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           L+VM    SKG A+  + + LG++ +  ++FGD  ND EML  +     M +AH  +K L
Sbjct: 184 LDVMNAEASKGAAIRHLQQTLGFTRQQTMSFGDYFNDVEMLKQSYHSYAMANAHPEVKAL 243

Query: 242 HPELEVIGTNADDAVPHYLRKLYLS 266
                +  +N +  V   +++  LS
Sbjct: 244 A--RFIAPSNEESGVLQVIQQQVLS 266


>UniRef50_C5NUB3 Hydrolase n=3 Tax=Firmicutes RepID=C5NUB3_9BACL
          Length = 430

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 68/289 (23%), Positives = 124/289 (42%), Gaps = 29/289 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASD+DGTLL+ +H +     + +     +GI FV ATGR + +     +   I  
Sbjct: 1   MIKLIASDMDGTLLNHNHKIPKENVKLINFAKNQGIEFVVATGRAYYEALPALNEENINC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM------- 113
            +I+ NG  V+D +GN+I    +          ++    DI   +Y  +  +        
Sbjct: 61  DVISFNGGIVYDKNGNIISITPMLPKDLYYTIEILKSF-DISYQLYTKNTIYTTSIETDT 119

Query: 114 ---------NRHRPEEMRFFKEA--------VFQYALYEPGLLEPEGVS-KVFFTCDSHE 155
                    N + P+      EA        + +    E  L E E    K+    +   
Sbjct: 120 NAYIDLIRSNGYEPDVEHLRAEAQQKLEVGYITEVENIELYLNEKENPPIKIIAISNDIS 179

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           +L    + ++      ++V+ S    +E+M    +KG AL+ +AK  G +L++ +A GD 
Sbjct: 180 KLENAAKLLSE--NTSISVTSSGANNIEIMHKNATKGTALKEIAKIYGINLENAVAIGDN 237

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +ND  ML + G    M + + +LK+    +    TN++  V   + KL 
Sbjct: 238 LNDQAMLDIVGYSVAMKNGNIKLKEQAKYVT-EKTNSEGGVADTIFKLI 285


>UniRef50_C4V674 HAD superfamily hydrolase n=2 Tax=Selenomonas RepID=C4V674_9FIRM
          Length = 275

 Score =  224 bits (571), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 61/265 (23%), Positives = 108/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A DLDGTLL+ D T++   K+ L    ARG+    ATGR           L  ++ 
Sbjct: 14  IKLIALDLDGTLLTSDKTITARTKDILARAMARGVTVTIATGRMLCSALYFVRLLGSRAP 73

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I  NG  V   +G+ +FA   D  +  +         D   N Y   E +   +R E  
Sbjct: 74  VICCNGGYVGTAEGDPLFARYFDPALVREFLAFCYAR-DWYVNWYNGIEIYAPEYRAECF 132

Query: 122 RFFK-EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             ++  A F         L        F   +    +      + A +G R+    +T T
Sbjct: 133 AAYRTTANFVVTEVGSDYLGCTENVPQFVLREMKSGVDSYVSEVRAHFGGRLVPQQNTGT 192

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            +++   G++K   ++A+A  +G +L + +  GD  ND +MLSM     +  +     K 
Sbjct: 193 SVDINPPGINKAVGVQALADAMGLTLDEVMVAGDADNDLDMLSMGAFSVVPANGLPAAKA 252

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 +  +N ++ +   + K  L
Sbjct: 253 RAS--YITASNDENGIAAAVEKFVL 275


>UniRef50_B4SM39 Cof-like hydrolase n=4 Tax=Bacteria RepID=B4SM39_STRM5
          Length = 277

 Score =  223 bits (570), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 64/270 (23%), Positives = 101/270 (37%), Gaps = 9/270 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            ++VA D+DGTLL P HTL+  AK+ +    A G++ V  +GR    +      L I   
Sbjct: 10  IELVAIDMDGTLLDPTHTLTVRAKQAIAQARALGVHIVLTSGRPVPGLAPFLHELGITGD 69

Query: 59  KSYMITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y I  NG  V  +     +  + L  D       V  D   +          +     
Sbjct: 70  DDYCIACNGGLVQRIGTRETVVEYPLSFDNFLFCEQVARD-LGVHFQALDSRRMYTPNQD 128

Query: 118 PEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                     + +  L       ++P          D+ + L      + +   +R  V 
Sbjct: 129 ISYYTVADSHLSRMPLSYRRVEDMDPSMSFIKLMMIDAPDVLDAAIARLPSELTERFAVL 188

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LEV      KG +L+ +A+ LG    + +A GD  ND  ML  AG    MG+A 
Sbjct: 189 KSAPFFLEVFDHRAGKGPSLQKLAEHLGIDRANVMAIGDQENDLTMLQYAGTSVAMGNAI 248

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +K +        +NAD+ V   + +  L
Sbjct: 249 DAVKAVA--RFETTSNADEGVARAIERFVL 276


>UniRef50_C4L3T6 Cof-like hydrolase n=2 Tax=Exiguobacterium RepID=C4L3T6_EXISA
          Length = 270

 Score =  223 bits (570), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 105/269 (39%), Gaps = 19/269 (7%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A DLDGTLL  D T+S      L+     G   + ATGR         + + + + ++
Sbjct: 5   LIAVDLDGTLLRDDKTISERNLRALQAAREAGHEVMIATGRPKRHSIMYYEQMGLTTPLV 64

Query: 64  TSNGARVHDLDGN--LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
             NGA VH        +    +    A D+   V D       V   D  +  +   E  
Sbjct: 65  NFNGALVHHPKDASYAVTHRPIPLKTAHDIIEEVADTKAHNIVVEVTDHVYFQKDPQEFY 124

Query: 122 RFFKE--------AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
             + E         + ++   EP  L             S    +  E  +N +W     
Sbjct: 125 SPYAERALSVTSGNLLKHLQDEPTSLLIHATKDHVAHVRSQLDDIHAEAVLNRQW----- 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
                   +EVM+   SK   L+ V+K L    K  IAFGD  ND EML   G G  MG+
Sbjct: 180 --RMPEHMIEVMSKNTSKALGLQEVSKHLNIDRKHIIAFGDEENDLEMLDYVGTGVAMGN 237

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRK 262
           A  +LK++    EV  +N DD +  +L +
Sbjct: 238 AIDQLKNVAN--EVTASNMDDGIALFLEE 264


>UniRef50_A7AZV2 Putative uncharacterized protein n=1 Tax=Ruminococcus gnavus ATCC
           29149 RepID=A7AZV2_RUMGN
          Length = 257

 Score =  223 bits (570), Expect = 5e-57,   Method: Composition-based stats.
 Identities = 75/265 (28%), Positives = 117/265 (44%), Gaps = 11/265 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASDLDGTLL  D ++S Y  + +K   A GI +V  TGR       I +N  +  
Sbjct: 1   MIRMIASDLDGTLLRKDWSISEYTIKIIKEAQASGIRWVTVTGRSDRGARPIMENYGLSC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVV-NDNPDIITNVYRDDEWFMNRHRPE 119
             I  NGA   D +GNLI + N+D D+A  +   +  +N     N  R D +       E
Sbjct: 61  DYILMNGAEFRDTNGNLIKSENIDTDLARFVCEKLHRENLGFEINTDRGD-YTTTMELAE 119

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
              + ++       YE    E   + K+   CD   ++  ++Q I    G  ++V  S  
Sbjct: 120 YSDYLEDG------YEKLFEEKHNIRKILVFCDDIPKIRRIKQQIYDASG--LSVLSSFE 171

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +EV +    KG  L+   K  G+  ++ + FGDG ND  M         M +    LK
Sbjct: 172 NNMEVTSQKAKKGIMLKQAMKHFGFLPEEVVVFGDGENDISMFQEFPCSYAMINGVDALK 231

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
           +L   +    +N +D V   L K+ 
Sbjct: 232 ELAYRVTEY-SNDEDGVAKTLEKIL 255


>UniRef50_C2KAT0 Possible sugar-phosphatase n=1 Tax=Chryseobacterium gleum ATCC
           35910 RepID=C2KAT0_9FLAO
          Length = 266

 Score =  223 bits (569), Expect = 5e-57,   Method: Composition-based stats.
 Identities = 64/266 (24%), Positives = 108/266 (40%), Gaps = 4/266 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++ +D+DGT L+  H +SP   E  K L  R I FV A+GR    +      +E +  
Sbjct: 4   IKLIVTDMDGTFLNSSHEMSPEFSEVYKELKKRNIVFVPASGRQMPGITHYFGEIESEIG 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            I  NG  V       +FA  L+     D+   V + P     +      +      + +
Sbjct: 64  FIAENGGYVI-YKDQELFADTLEYKYIVDIIKAVREIPGAKAVLSAKKMAYYETEDQQFV 122

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            FF +   +    +    + +  +              L  A+       + +  S    
Sbjct: 123 DFFSKYYTENMKKDDLTEKIDDTAFKIAVYHPEGSEKHLYPALKKFEEFGLEIVVSGAHW 182

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           L+VM   ++KG+AL+ + K LG S ++ +AFGD MND EML  A     M +AH  +K +
Sbjct: 183 LDVMNKDINKGNALKILQKSLGISPENTMAFGDYMNDIEMLKNAKYSYAMQNAHPNVKQV 242

Query: 242 HPELEVIGTNADDAVPHYLRKL-YLS 266
                   TN    V   ++   +L+
Sbjct: 243 AN--FEACTNDSFGVLKTIKDYLHLN 266


>UniRef50_C7XLV6 Putative uncharacterized protein n=1 Tax=Lactobacillus crispatus
           125-2-CHN RepID=C7XLV6_9LACO
          Length = 273

 Score =  223 bits (569), Expect = 5e-57,   Method: Composition-based stats.
 Identities = 66/275 (24%), Positives = 119/275 (43%), Gaps = 12/275 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A DLDGTLL+    +   + + +K     GI  V  TGR  V V    + L++  
Sbjct: 1   MIKLIAIDLDGTLLNDHGEILQNSIKAIKEAKNYGIKIVLCTGRPLVSVTPFLEQLQLTN 60

Query: 59  --KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF-MNR 115
               Y+IT NG+ +    G +I     D     D F +  D   + T +   +  + +N+
Sbjct: 61  FNDQYVITFNGSIIETTAGKVIKQQTFDFQTFVD-FELWADKIALYTQLENQEALYTINQ 119

Query: 116 HRP----EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
           + P     E    K  +   +L++   +  + V        S E+L  ++  I     D+
Sbjct: 120 NIPIDAAHESWKNKLPIHVTSLHDLIAMPQKPVMLKIMAVASKEKLDEIQHKIPNDLLDK 179

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           ++   S    L+  A  V KG AL+ + + L  + ++ +A G+  ND  M+  AG G  M
Sbjct: 180 LSPIRSEPMYLDFAAPNVDKGWALKKLTQYLHLNRQEVMAIGNADNDVPMVKYAGVGVAM 239

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +  RL  +     + G+N    +   + K+ L+
Sbjct: 240 EKSTPRLLQVAD--YITGSNNTTGIADIINKMILT 272


>UniRef50_Q8ELU0 Hypothetical conserved protein n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8ELU0_OCEIH
          Length = 294

 Score =  223 bits (569), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 71/287 (24%), Positives = 127/287 (44%), Gaps = 30/287 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ASDLDGTLL  D T+S   ++ ++    +GI F+ ATGR +       +   I   +
Sbjct: 2   KLIASDLDGTLLQEDGTISEANQKAIQAAIDKGIEFIVATGRSYDAARIPLEKAGIDCSV 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM--------- 113
           I+ NGA  +  +  +I +  L++D+A  +  V  D   +   ++ +   +          
Sbjct: 62  ISLNGAVSYTKEKEIIRSIPLEKDVAKQITDVC-DQEGMYIELFTNKGIYSGSREYFLEV 120

Query: 114 ---------NRHRPEEMRFFKEAVFQYALYE-----PGLLEPEGVS--KVFFTCDSHEQL 157
                         +++R   E  FQ+   E       +L+   ++  K+       EQL
Sbjct: 121 MVDIMTSANPNISEKDVREQAERRFQFEPVEFINDYHAVLDSTDINVYKILVFATEPEQL 180

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
               + + +  G  V ++ S    LE       KG A+E   ++  ++++D ++ GD  N
Sbjct: 181 SNASEKLRSEEG--VVITSSGEINLEFNHPEAQKGLAVEQYVQQKQWTMEDVMSIGDNWN 238

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           DA ML MAG+G  MG+A   +K L        TN +D V   L ++ 
Sbjct: 239 DASMLQMAGRGVAMGNAADEIKALCS--YTTLTNREDGVAVALEEML 283


>UniRef50_D2RIN9 Cof-like hydrolase n=2 Tax=Acidaminococcus RepID=D2RIN9_ACIFE
          Length = 269

 Score =  222 bits (568), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 67/264 (25%), Positives = 114/264 (43%), Gaps = 8/264 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLL  +  ++P     +K   A G     ATGR +         L +   +
Sbjct: 4   KMIAMDLDGTLLDEEKNIAPEDAAAVKDAVAAGYYVTLATGRMYRSALPYAQELRLTHPL 63

Query: 63  ITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +  NGA + D   G  +    L  D+A  +   +     I    Y DD  +  R   E  
Sbjct: 64  VVYNGALIRDPGTGENLGQWPLPLDVAQSVLDDLL-GWGIYVQAYVDDTLWAPRDCEEVR 122

Query: 122 RFFKEAVFQYALYEPGLLE-PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            + + +   Y +    +   P+   K+    D   Q+  L   +  ++  ++ +  S+  
Sbjct: 123 FYSRFSRVPYEVKTEAIRHLPQAPHKLLVISD---QVRTLRPELEEKYRGKIKIVSSSKG 179

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LEV A G +K HAL+A+A + G   ++ +  GD  ND EM+S AG G  MG+A   +++
Sbjct: 180 FLEVTAPGTNKWHALQALAAREGIREEEILCVGDSDNDLEMISHAGFGVAMGNASDPVRE 239

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                 V   N  + V   +R + 
Sbjct: 240 AA--RVVTAPNTRNGVARIIRTIL 261


>UniRef50_UPI0001C430CB Cof-like hydrolase n=1 Tax=Bacillus pseudofirmus OF4
           RepID=UPI0001C430CB
          Length = 277

 Score =  222 bits (568), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 57/253 (22%), Positives = 111/253 (43%), Gaps = 7/253 (2%)

Query: 18  HTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY---MITSNGARVHDLD 74
           HT+S   KE L      GI  V A+GR    +  + + L++  Y   +++ NGA++ +  
Sbjct: 24  HTISSRTKEALMQAQKNGIKVVLASGRPTYGMVPVANELKLADYGSFILSFNGAKIINSK 83

Query: 75  -GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYAL 133
               +++  L      +L+  V+   ++  + Y +++     +    M   +        
Sbjct: 84  TNEEMYSSTLSPKQLHELY-HVSQRENVGIHTYMENDIVTEANNEYTMIEGEITGMPVIE 142

Query: 134 YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGH 193
            E  +   +            ++L+ +E+ +   +  +++V  S    LE    GV+KG 
Sbjct: 143 VERFVDAVDEPCVKALMVGHPDRLVEVEKKLQEEFRGQLSVMRSKPYFLEFTEDGVTKGA 202

Query: 194 ALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNAD 253
           +L ++  KLG   ++ IA GD  ND  M+  AG G  MG+A   +K++     V  TN +
Sbjct: 203 SLHSLITKLGIKQEEVIAMGDSYNDQTMIEFAGLGVAMGNAPDDIKEIAD--YVTDTNMN 260

Query: 254 DAVPHYLRKLYLS 266
           D V   + +  L+
Sbjct: 261 DGVAKVVEEFVLN 273


>UniRef50_B6WB05 Putative uncharacterized protein n=1 Tax=Anaerococcus hydrogenalis
           DSM 7454 RepID=B6WB05_9FIRM
          Length = 268

 Score =  222 bits (568), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 63/270 (23%), Positives = 121/270 (44%), Gaps = 8/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTL++  H ++   K TL      G   V A+GR    V  + + L+   
Sbjct: 1   MKKIIALDVDGTLVNSKHVITEKTKNTLLKCQKEGHILVIASGRDVEGVKDLAEELQFDK 60

Query: 61  Y---MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN-R 115
           Y   +   NG RV +   G ++F H    D ++++   V  N D+    ++D + + + +
Sbjct: 61  YNGLLSNYNGCRVTNFATGQVLFNHTFKIDQSNEIISFVK-NLDVEIFTFKDGKVYSDDK 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           +    +   K     Y + +      + ++       S +++  +   +   + ++  V 
Sbjct: 120 NNKSLIDTTKRLKIGYLIDKNMRNGIDFLANNMIIGASKDKIDQVYPIVQKEFENKYTVV 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            +T   +E M  G SKG +L  +AK      ++ IAFGD  ND  M  +      MG+A 
Sbjct: 180 RTTENYVEFMPRGFSKGSSLLEIAKYYNIDKENIIAFGDEENDYSMFDIGAFSVAMGNAS 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +++K+      V  +N +D + +YL    L
Sbjct: 240 EKIKEKAD--FVTKSNDEDGIAYYLENYLL 267


>UniRef50_A5UZ29 Cof-like hydrolase n=2 Tax=Roseiflexus RepID=A5UZ29_ROSS1
          Length = 271

 Score =  222 bits (568), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 69/270 (25%), Positives = 119/270 (44%), Gaps = 9/270 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           ++++A DLDGT++  D  + P  +ET+  + ARGI+   ATGR           L+I++ 
Sbjct: 3   FRLIALDLDGTVIDRDLVIHPDVRETIAAVQARGIHVTLATGRMFNAAMPFARELDIRAP 62

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I   GA V     G  ++   +     +        + DI    Y  D  ++  HR E 
Sbjct: 63  IICYQGALVRHPLTGETLYHATMPA-DLAAAAVHALLDADIFVIAYIHDVHYIAAHRSEL 121

Query: 121 MRFF----KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             +     +E     A     L+     +K+ F  +       L   ++ R+G+ + +  
Sbjct: 122 EAYLAFHPEENEIVVAPDLERLVARMAPTKLLFVAEPQVVEREL-ARLSDRFGEALAIIR 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S     E+ A  VSKG AL  +A+ LG + ++ +A GD  ND  M++ AG G  MG+A  
Sbjct: 181 SHAIFGELTAPHVSKGQALATLAESLGVAREEVMAIGDQENDLSMITWAGLGLAMGNAVP 240

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            ++       V+    +  V   LR+  L+
Sbjct: 241 AVRAQAHA--VLPPVGEAGVACALRRYVLN 268


>UniRef50_UPI0001C34D0C Cof-like hydrolase n=2 Tax=Clostridium RepID=UPI0001C34D0C
          Length = 275

 Score =  222 bits (568), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 70/278 (25%), Positives = 116/278 (41%), Gaps = 19/278 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A DLDGTLL+ D  LS   K  L+    RGI  V  TGR    + +    L+   Y
Sbjct: 3   IRLIALDLDGTLLTSDKRLSERNKRALEECIRRGIYIVPCTGRTFEGIPKPVRMLDGIKY 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRD----------DE 110
            I +NGA + D + G ++    L  + A  +   + D   ++ + Y +          D 
Sbjct: 63  TILTNGACIQDAETGEILERRGLFWEKAMQVIDRIEDFT-LMYDCYIEGRGKADRRFLDT 121

Query: 111 WFMNRHRPEEMRFFKEAVFQYALYEPGLLEPE---GVSKVFFTCDSHEQLLPLEQAINAR 167
                 RPE  R  +E        +  L + +       ++F     E    + + +   
Sbjct: 122 LEYYEIRPEICRLIRETRDPLPSLKDYLAKKQPLLDKMNIYFKGCDRETKQRVRRELAEI 181

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
            G  + V+ S    LE+   G +KG A+  +A +L   +   +AFGDG ND  M+ +AG 
Sbjct: 182 EG--LVVTSSMPNNLEINGEGATKGDAIRLLADRLKIPVSQTMAFGDGENDRSMMELAGV 239

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G  M +     K+      +  +N  D V   + +L L
Sbjct: 240 GVAMENGSPLAKECAS--YIAPSNDADGVAEIIERLVL 275


>UniRef50_C0CQY6 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C0CQY6_9FIRM
          Length = 267

 Score =  222 bits (568), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 59/265 (22%), Positives = 112/265 (42%), Gaps = 5/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLS-PYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
            ++VA D+DGT +  D+T   P  +  L  +   G +FV A+G  +  +  +        
Sbjct: 5   IKLVAVDIDGTFVRSDYTYDIPRFQRILSRMKNAGCHFVVASGNQYYQLRDLFPGYYNDL 64

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             +  NGA V   +  LIFA ++ ++    +     + P+I   +   +  +  R R  +
Sbjct: 65  SYVAENGAFVK-AETELIFAADMPKETVDFVVDTCREYPEIRNVLCGVESAYCERGRVNQ 123

Query: 121 MRFFKEAVFQYAL-YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
             F   +++ + L +     +       F      ++     + +  +   R+  + S  
Sbjct: 124 EFFDLTSIYYHRLKWVDDFKQVNDQILKFAPTVPEDKTHFYYEILGKKLKGRLEPTTSGH 183

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             ++++  G  K   L  +AK+ G   + C AFGDG ND EML   G    M +A + +K
Sbjct: 184 GSIDLIVPGCHKASGLRRLAKRWGILPEQCAAFGDGGNDIEMLQYCGYSYAMDNASENVK 243

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
           +      V  +N +D V   L +L+
Sbjct: 244 NAAKH--VCPSNEEDGVLVTLEELF 266


>UniRef50_D1PP54 HAD hydrolase, IIB family n=1 Tax=Subdoligranulum variabile DSM
           15176 RepID=D1PP54_9FIRM
          Length = 274

 Score =  222 bits (567), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 73/275 (26%), Positives = 120/275 (43%), Gaps = 15/275 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLDGT+ + +  +SP   + ++   A+G++ + ATGR    V +    +    Y
Sbjct: 4   IRLVALDLDGTVFNDEKQISPRTLDAIRAALAKGVDVLPATGRTVTGVPRQFAEIPGVRY 63

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN------ 114
            +TSNGA V DL  G  +     D  +A   F VV     ++ +V+ + E +        
Sbjct: 64  ALTSNGASVVDLQTGEKLVCLPFDAALAERAFDVVRPFGGML-SVFINGESYTAASTSGD 122

Query: 115 --RHRPEEMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
                PE +R +             ++E  P  + K F      E          A    
Sbjct: 123 GLEMVPENLREYFRTTRNVVPDMHRMMEEHPHEIEK-FSILYPTEAQRDAAWQAVAAACP 181

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + ++ S    +E+ A GVSKG  L A+AK+LG + +  +A GD  ND  M+ +AG G  
Sbjct: 182 TLEITSSIERNMELNAPGVSKGPGLMALAKRLGLAREQVMAVGDSGNDRTMVELAGLGVA 241

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           MG+A + ++       +   N  D V   + K  L
Sbjct: 242 MGNATEEIRQAAD--VITADNNHDGVAEAIEKYVL 274


>UniRef50_B0TIL9 Cof-like hydrolase n=1 Tax=Heliobacterium modesticaldum Ice1
           RepID=B0TIL9_HELMI
          Length = 275

 Score =  222 bits (567), Expect = 9e-57,   Method: Composition-based stats.
 Identities = 62/269 (23%), Positives = 102/269 (37%), Gaps = 8/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLDGTLL     +       +  L  +G+ F  ATGR +         LE+++ 
Sbjct: 8   IRLVAMDLDGTLLDEKRRIPEPVARRIAELRGKGVIFTVATGRIYPSALPYAKQLELEAP 67

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVN-DNPDIITNVYRDDEWFMNRHRPE 119
           MIT NGA +    DG +I    ++   A  +   +   N D +   +  DE + +     
Sbjct: 68  MITCNGAMIRHPADGRIICHRTVEAKQALAVLQFLKAKNSDALRYSFHGDEVYTDTPHEY 127

Query: 120 EMRFFKEAVFQYALYEPGL----LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
              + +     +   +        EPE    +            L Q I A     V ++
Sbjct: 128 TTSYERGLGLSFTFVDDLTAHLAKEPERHPTMLVLMTDPAVTPALTQDILAHLNGTVTIT 187

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    +E++    SKG AL  +A        + +A GD  ND  M+  AG+G  + +A 
Sbjct: 188 NSHDYFIEILHPEASKGAALAQLAASFSIDRSEVLAIGDNRNDLTMIHWAGQGVFVANAP 247

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           + L        V   +    V   L   +
Sbjct: 248 EVLHQAAD--YVTSASNSMGVLEALNYFF 274


>UniRef50_P42962 Uncharacterized protein ycsE n=9 Tax=Bacillus RepID=YCSE_BACSU
          Length = 249

 Score =  222 bits (567), Expect = 9e-57,   Method: Composition-based stats.
 Identities = 64/264 (24%), Positives = 127/264 (48%), Gaps = 24/264 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A D+DGTLL+ +  +S   ++ ++    +G+  V +TGR  +   ++ ++L++ S+
Sbjct: 10  IKLIAIDMDGTLLNDEQLISDENRKAIREAEDKGVYVVISTGRTLMTCRELAESLKLSSF 69

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +IT+NG+ + D + NL+    L  D    ++ + N +         +  W      PE +
Sbjct: 70  LITANGSEIWDSNFNLVERKLLHTDHIQMMWDLRNKHNTNFWASTVNKVW--RGEFPENI 127

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
              +   F + + +  +               +E L  L +         + ++ S+ T 
Sbjct: 128 TDHEWLKFGFDIEDDDI--------------RNEVLEELRK------NKELEITNSSPTN 167

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +EV A G++K  AL  V +KLG+++++ +A GD +ND  M+  AG G  MG+A   +K+ 
Sbjct: 168 IEVNALGINKAAALAKVTEKLGFTMENVMAMGDSLNDIAMIKEAGLGVAMGNAQDIVKET 227

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                +  TN +D V   +R   L
Sbjct: 228 AD--YITDTNIEDGVAKAIRHWVL 249


>UniRef50_C9LLD7 HAD hydrolase, IIB family n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LLD7_9FIRM
          Length = 266

 Score =  222 bits (567), Expect = 9e-57,   Method: Composition-based stats.
 Identities = 67/266 (25%), Positives = 115/266 (43%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
            ++ A DLDGTLL  D +LS ++K+ ++    RGI+ V ATGR         + L +  +
Sbjct: 3   IKMAAIDLDGTLLHDDMSLSDFSKDIIRKAEHRGIHIVLATGRMFDAARPKAEELGLSDT 62

Query: 61  YMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +I   GA +     G  I+   +D  +A  +     +    + + + DD+ ++      
Sbjct: 63  PLICYTGAWIMMSRSGRPIWQDGIDISVAEKILLTAREK-GWLVHTFFDDQIYLPEPNKT 121

Query: 120 EMRFFKEAVFQYALYEPGLLEPEG-VSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           E ++ K      A        P+   +++ F   S      + + I   + D V V F  
Sbjct: 122 EAKYKKYRTKAVAYLGNAFYHPKKKPTRLIFADGSEAVRREIRRVIETNFSDEVEVVFPG 181

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              ++V   GVSKG AL+ +      SL + IAFG+  ND  ML MAG    + +A +  
Sbjct: 182 DDFVDVHKKGVSKGTALQKLCNMWDISLSEVIAFGNTENDVSMLKMAGISYAVKNADEYA 241

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           +       +  +N +D V   L +  
Sbjct: 242 RSAAGN--ICDSNENDGVAKVLAEYL 265


>UniRef50_Q5WGE2 HAD superfamily hydrolase n=2 Tax=Bacillus RepID=Q5WGE2_BACSK
          Length = 289

 Score =  222 bits (567), Expect = 9e-57,   Method: Composition-based stats.
 Identities = 71/287 (24%), Positives = 116/287 (40%), Gaps = 29/287 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ +D+DGTLL    ++S   +E +K    +G     ATGR   +         +   +
Sbjct: 2   KLIVTDMDGTLLDEKRSVSKENEEAIKAAQKQGAVVAIATGRDLYEATVPLKKTGLSLPI 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP---- 118
           I++NGA++HD  G L+    L  D A     V+  N ++   VY ++  + +        
Sbjct: 62  ISANGAQIHDEHGRLLHEAVLSPDQARHAMAVLK-NENVYFEVYTNEGVYSDDFEAGLAV 120

Query: 119 ---------------EEMRFFKE-----AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLL 158
                          E M F K+     ++     YE  L +   V K+       ++L+
Sbjct: 121 VVDVLKSTGAKLSEQEIMTFAKDRFDNGSIKLIDCYEKLLEDGAVVLKLLAFSLDAKRLM 180

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
                +         VS S    LE+      KG A+E +A+ LG S KD +A GD  ND
Sbjct: 181 SARDRLE--LDKNFAVSASAADNLEITDVNAQKGIAVERLAQSLGISPKDVMAVGDNFND 238

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             M   AG    MG+A   ++       V  TN +  V + +R   L
Sbjct: 239 VSMFQKAGLAVAMGNAPGEIQKQADL--VTKTNDEHGVAYAIRNYAL 283


>UniRef50_A6TMX9 Cof-like hydrolase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TMX9_ALKMQ
          Length = 293

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 72/286 (25%), Positives = 127/286 (44%), Gaps = 28/286 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A+D+DGTLL  D  LS    E L      GI+    TGR    V    + L I  +
Sbjct: 3   YKLLATDMDGTLLMDDKALSTENIEALTRGKEHGIDLAICTGRPFPTVKPYLEQLGISCW 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           ++T+NG+ + D   N+I+   +++D    +  +     D+  +V   +  ++ + R + M
Sbjct: 63  LVTNNGSVIRDKQENIIYEKFMEQDALEKIIDIFESEKDLYYHVSDANHTYI-KSRRQRM 121

Query: 122 RFFKEAV-----------------------FQYALYEPGLLEPEGVSKVFFTCDSHEQLL 158
           R  ++ V                        +   +   +     V+ VF     + QL 
Sbjct: 122 RTIQKFVSIKNMSPIKAYVTAAKMVFLSGTHKKVDFLSYVKNGGKVASVFVYSKDNIQLN 181

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
            L++ ++      +NV+ S    +E++ G  +KGHALE ++KKL    ++ IA GD  ND
Sbjct: 182 RLKEKLSEIKS--INVTSSGSDNIEILDGNATKGHALEYLSKKLDIQAEEMIAVGDNYND 239

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             M+  AG G  M +  Q + D      V  TN ++ V   + K+ 
Sbjct: 240 LSMIQYAGLGVAMRNGEQAIIDEADW--VTKTNQENGVAFLMEKVL 283


>UniRef50_C4FTB9 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FTB9_9FIRM
          Length = 274

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 63/269 (23%), Positives = 115/269 (42%), Gaps = 10/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           YQ++  D+D TL++ ++T+S    + L     +G   V A+GR    + +    L++   
Sbjct: 4   YQMLVLDIDDTLMTSENTISDATYQALMKAQEQGKKVVLASGRPTPSMIETAKQLKLDHF 63

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
            SY+I+ NGA +  + DG  +F+  L+ +   D+   +     +    Y DD   M++  
Sbjct: 64  DSYIISFNGAAITSMADGQELFSQRLEAEAQDDIVRYIQAK-GLTVLTYMDDYVVMDKAN 122

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSK---VFFTCDSHEQLLPLEQAINARWGDRVNV 174
                  +            +     ++K    F      + +   +  +  R+G+    
Sbjct: 123 DYSHIESQLTGIPDRYDPEAIANLSQLAKARMKFIGVGDPDLVAAADAELEGRFGELTYA 182

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           + S    LE +   VSKG A++ + + LG +L   IA GDG ND  M+  AG G  M +A
Sbjct: 183 TTSKPYFLEFVHHQVSKGQAIKVLCQHLGLTLDQVIACGDGNNDLTMIETAGLGVAMANA 242

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKL 263
              LK+      +  +N  D +   +R  
Sbjct: 243 TPLLKEAADH--ITLSNDQDGLVPIIRDF 269


>UniRef50_C6CZV3 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CZV3_PAESJ
          Length = 250

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 59/264 (22%), Positives = 102/264 (38%), Gaps = 19/264 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++VA D+DGTLL+    +S    E ++     GI   F+TGR         + L++++ 
Sbjct: 4   YKLVALDMDGTLLNDQSEISEENAEWIQRALDAGITVSFSTGRGFRGALPFAEQLKLETP 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           MIT+NG+ +      L     L       L  +   +       Y     +         
Sbjct: 64  MITANGSEIWQRPHVLHKRTLLSPVYVKQLHELALKHEGTWFWAYSTTGIY--------- 114

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
                   +  +      E     K  +  +       +   I     D + ++ S+   
Sbjct: 115 ------NLEKWIDPSTTYEDHHWLKFGYYTEDDVIRNRILAEITEW--DALEITNSSTQN 166

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+   G++K  AL  +   LG  +   +A GD +ND   +  AG G  MG+A Q +KD 
Sbjct: 167 LELNPKGITKASALRELCTMLGIEMSQVVAAGDSLNDIAAIREAGLGVAMGNAQQAVKDA 226

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                V  TN ++ V   +++  L
Sbjct: 227 ADA--VTLTNNENGVAEIIKQYVL 248


>UniRef50_Q042H4 Predicted hydrolase of the HAD superfamily n=11 Tax=Lactobacillus
           RepID=Q042H4_LACGA
          Length = 286

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 64/272 (23%), Positives = 120/272 (44%), Gaps = 13/272 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS-- 60
           +++A DLDGTLL+    +S   +E L+  +  GI  V  +GR    + +  D L+++   
Sbjct: 19  KLIAVDLDGTLLNDKQEISVKTREALQKASRLGIKIVPCSGRPFPGIKEYLDQLDLQDPN 78

Query: 61  -YMITSNGARVHDLDGNLIFAHNLDRDI---ASDLFGVVNDNPDIITN-VYRDDEWFMNR 115
            Y++  NGA V +  GN +    L          +   +  N  I  +  +   + F+N 
Sbjct: 79  QYVVAFNGALVLNAQGNAVVEELLSYQDFLFFEKIAQQLKANFHIEVSDKFITLDHFINY 138

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           +   E    + ++         + +    +K  F+    E +  + + +     ++ NVS
Sbjct: 139 YLSRESWLTRMSIEVCGF--KDIAKDLKFTKAMFSGAPSE-MERVYRHLPKEVIEKYNVS 195

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG-KGCIMGSA 234
            S  T +E+ +   SKG+AL+ +A+KL     + + FGD  ND  M  +       MG+A
Sbjct: 196 TSDKTLIEINSKQASKGNALKELAQKLNLRQDEIMIFGDQKNDISMFDVPDFYKVAMGNA 255

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              +K       V  TN +D + + +R+L  +
Sbjct: 256 VLEIKKRAN--YVTRTNNEDGIAYAIRRLIFN 285


>UniRef50_B6FMU0 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
           1787 RepID=B6FMU0_9CLOT
          Length = 269

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 63/272 (23%), Positives = 128/272 (47%), Gaps = 12/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+D T ++  H ++   KE L+ + A+GI+ V  TGR    +      +E  S
Sbjct: 3   MIKLLAVDMDETAVNSRHRMTKVTKEALREVYAKGIHVVPVTGRCLEGLPANMRGMEELS 62

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
           Y+ITSNGA+V+D  +  +++   +  + A D+  +   +  +   ++++ + + N     
Sbjct: 63  YIITSNGAKVYDWKEKEVLYRKLISNETACDVLKICQQDA-LGIAIHQEGKCYDNSKVQA 121

Query: 120 EMR---FFKEAVFQYALYEP---GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
             R   +  +   + A+ +         + + K+       E+L  ++  +     D + 
Sbjct: 122 LYRKLAYHGDFKMREAIKDLCGFVKKSGKPIEKIQVFSGKKEKLESIKNKLEPF--DDLE 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           ++ ST   +E+      KG ALE + + LG  +++ +A GD  ND  ML  AG    MG+
Sbjct: 180 LAISTSGYIEITQKDAQKGKALEHLCRYLGIHMEEVMAIGDNENDHSMLVRAGYPIAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A++ +K +     V  +N +  V   + +  L
Sbjct: 240 ANEEIKKIAK--YVTASNDESGVAKAIYEKLL 269


>UniRef50_P74365 Sll1524 protein n=1 Tax=Synechocystis sp. PCC 6803
           RepID=P74365_SYNY3
          Length = 279

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 113/272 (41%), Gaps = 10/272 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++V  D+DGT+    + ++P   +T+  + +RGI    ATGR      +    ++    
Sbjct: 3   IKLVVLDIDGTIAGVSNQINPSVVKTIHQVQSRGIQVALATGRMFSSALRFHQTIQSTLP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVND---NPDIITNVYRDDEWFMNRHR 117
           +I+ NGA       G ++    L   IA ++          P +  + Y +D+  +    
Sbjct: 63  LISYNGALTKHPHTGAVLREKPLPPAIALEILDHFERPELEPHLDIHCYYNDQLHVRHIT 122

Query: 118 PEEMRFFKEAVFQYALYEP--GLLEPEGVSKVFFTCDSHEQLLPLEQAINARW-GDRVNV 174
           PE   + + +            ++E    +K+     +   +  L   +  +  G  V++
Sbjct: 123 PETHVYMERSGAMAQASGDLRSIIELGSTTKMLAISRNAPLMAQLMAEMGQKLQGQAVHL 182

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKK-LGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           + ST    EV     +KG AL+ +A+  LG   ++ +A GD  ND EML  AG G  MG+
Sbjct: 183 TQSTEIYFEVTHAEATKGLALQHLAEDVLGLDPQEVLAIGDNFNDVEMLKYAGVGVAMGN 242

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A   ++ +     V      D V   L +  L
Sbjct: 243 APPEVQKVADW--VTADVEADGVSQALARFCL 272


>UniRef50_Q042G1 Predicted hydrolase of the HAD superfamily n=8 Tax=Lactobacillus
           RepID=Q042G1_LACGA
          Length = 286

 Score =  222 bits (566), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 73/291 (25%), Positives = 121/291 (41%), Gaps = 35/291 (12%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASD+DGTLL+    +S      +K   A+GI F+ ATGR   +   I     + +
Sbjct: 1   MIKLIASDMDGTLLNKQMQISSENISAIKEAQAKGIEFLVATGRAPSESQGILAKAGLHT 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR--- 117
             I  NGA V + +G LI    + ++ +  +  ++ D+      V  D  +  +R R   
Sbjct: 61  GFINLNGAMVFNTEGKLIVNEPIPKEESFKINKLLKDSGFYFEIVGADHVYSDSRLRRIA 120

Query: 118 -------------------------PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCD 152
                                     E M+      F+  L +P     E +  V F  D
Sbjct: 121 NFSDLLVDLNKKLTFKKAVSFAAGSDEIMKIKYVPDFKDLLKKPSF---EAMKFVAFHPD 177

Query: 153 SHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAF 212
             +    + Q I       + V+ S+ T +E+      KG AL   AK  GY   + +A 
Sbjct: 178 GPKVFNHIRQEIKKI--GDLIVTASSSTNIEINNIKAQKGIALMDYAKLQGYQPDEVMAI 235

Query: 213 GDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           GD +ND  M+ MAG G  M +A   +K++     +  TN ++ V + +R  
Sbjct: 236 GDNLNDESMIRMAGIGVAMENAAPEIKEIAN--FITKTNNENGVAYAIRHF 284


>UniRef50_A5ZMH1 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A5ZMH1_9FIRM
          Length = 295

 Score =  221 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 60/269 (22%), Positives = 109/269 (40%), Gaps = 9/269 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK--- 59
           +++ +DLDGTLL+    ++   +  +    A G   V  TGR             +    
Sbjct: 25  RILFTDLDGTLLNDHKEVTSGNQVAIDEALACGHKIVVCTGRPLASARVCAAKAGLDKEG 84

Query: 60  SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y+I  NG +++D      ++     ++ A+ + G      D+    Y D      R   
Sbjct: 85  CYVICFNGGQIYDPYHEKTVYGKTFSKETAAKIIGEAMKR-DLHIQSYSDTHILSARDTE 143

Query: 119 EEMRFFKEAVFQYALYE-PGLLEPEGVSKVFFT--CDSHEQLLPLEQAINARWGDRVNVS 175
           E  R+ K     Y + E    + PE   K+      +  E+ +  ++ + +++   V+  
Sbjct: 144 ELHRYAKINQLPYKVVECAADVVPEDPYKLIAITPAEQKEKNICFQKEVISQYAGEVHSF 203

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
           FS     E++  G+SKG A+      LG  +++ +A GD  ND EML  A  G +M +A 
Sbjct: 204 FSNDCYQEIVPEGISKGFAVRWFCDYLGIPIENSVAAGDAQNDVEMLKAAHVGAVMCNAF 263

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             + +    +     N  D V   + K  
Sbjct: 264 PGIAEYGNYVT-EHDNNHDGVAEIIHKFI 291


>UniRef50_Q45494 Putative phosphatase ykrA n=4 Tax=Bacillus RepID=YKRA_BACSU
          Length = 257

 Score =  221 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 58/263 (22%), Positives = 111/263 (42%), Gaps = 11/263 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  D+DGT+   D  +    ++T+  L  +G +   A+GR    V  I + L I S+ 
Sbjct: 4   KLIFFDIDGTIYDHDKNIPESTRKTVAELQRQGHHVFIASGRSPFLVKPILEELGIHSF- 62

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I+ NG  V   +  +I+ + L  +    L    ++    +  +  D         P  + 
Sbjct: 63  ISYNGQFVV-FENQVIYKNPLPENAIRRLLKQADEGKHPVVFMAEDTMKATVADHPHVLE 121

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
                   Y   +    E + + ++   C   E     E+A  A      ++        
Sbjct: 122 GIGSLKTDYPETDDLFYEGKEIFQLLLFCQDEE-----EKAYAAF--PEFDLVRWHELST 174

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +V+  G SK   ++ V ++L + + D  AFGDG+ND +M+   G G  MG+A   LK++ 
Sbjct: 175 DVLPHGGSKAEGIKKVIERLPFDIGDTYAFGDGLNDLQMIEYVGTGVAMGNAVPELKEIA 234

Query: 243 PELEVIGTNADDAVPHYLRKLYL 265
               V     +D + + +++L L
Sbjct: 235 D--FVTKPVDEDGIAYAVKELGL 255


>UniRef50_C6W4G6 Cof-like hydrolase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6W4G6_DYAFD
          Length = 265

 Score =  221 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 59/262 (22%), Positives = 112/262 (42%), Gaps = 4/262 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA+D+DGTLL+  H +        + L   GI FV A+GR + ++ +  D ++ +  
Sbjct: 6   IRLVATDMDGTLLNSKHEIHESFFPVFRKLRDHGIIFVAASGRQYFNLAKTLDAVKEEVI 65

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
               NG+ V   +   I    +D++I  +L  V     +    +    + ++     E +
Sbjct: 66  FAAENGSYVV-CNDEEIHIQAVDQEITHELIRVARKIKNTYPIICGKKKAYVENDDEEFI 124

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
              K    +Y + E  L   +     F  CD     +        ++ + + V  S    
Sbjct: 125 NHLKLYFERYEVVEDLLEIRDDQFLKFTLCDLAGSEVNSYPHYK-KYENDLQVKVSGPIW 183

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           L++     +KG A+E + +K   + K  + FGD +ND EML  A     M +AH  +K +
Sbjct: 184 LDISHKKANKGRAMEVLQEKFNITAKQTMVFGDYLNDLEMLEKAHYSYAMANAHPDIKKI 243

Query: 242 HPELEVIGTNADDAVPHYLRKL 263
                +  +N ++ V   L ++
Sbjct: 244 A--RFIAKSNDENGVVEVLSEI 263


>UniRef50_C9PP31 Phosphatase YbhA n=1 Tax=Pasteurella dagmatis ATCC 43325
           RepID=C9PP31_9PAST
          Length = 276

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 59/270 (21%), Positives = 109/270 (40%), Gaps = 17/270 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           YQV+A DLDGTLL+    +   +K  ++    +G   V  TGRHH         L + + 
Sbjct: 3   YQVIAFDLDGTLLNSKGQILTSSKAAIQRCINKGFKVVLVTGRHHTAAYPYYHELNLTTP 62

Query: 62  MITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           MI  NG  V+    + ++ A+ L  + A  +  +  +   +   +Y  +E   +      
Sbjct: 63  MICCNGTYVYQPQTDSVLSANPLSFEQARTIIQLA-EKYGMHLLMYSRNEMNYSSLNEHM 121

Query: 121 MRF----------FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            +F           +  + + + +   L + E + K   +    +    ++  +NA    
Sbjct: 122 RKFSKWVESCPEAIRPKIREVSDFNGLLKDGEIIWKFVISHPDRDL---MQATVNALPSS 178

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
             +  +S     ++   G +KG  L  +        +  +AFGD  ND  MLS  G G  
Sbjct: 179 EFSCEWSWFDRADIANRGNTKGTRLLELLNSWRIDPQAVVAFGDNHNDISMLSAVGLGIA 238

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
           MG+A   +K+      V  +N ++ +   L
Sbjct: 239 MGNAETEVKECAKL--VTLSNDEEGIASVL 266


>UniRef50_C8ZWL6 Hydrolase n=9 Tax=Lactobacillales RepID=C8ZWL6_ENTGA
          Length = 278

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 72/276 (26%), Positives = 115/276 (41%), Gaps = 17/276 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++ SD+DGT+L   H + P  ++ L+ L    I FV A+ R    +  + + L I  Y
Sbjct: 6   IKLIVSDIDGTILDDTHQIDPNLQQVLQRLKESKIPFVLASARSPKGMQHLAEALGISEY 65

Query: 62  -MITSNGARVHDLDGNL----IFAHNLDRDIASDLFGVVNDN-PDIITNVYRDDEWFMNR 115
            +   NGA V   +GNL    I +H +       +      +   +  N+Y D  W+++R
Sbjct: 66  PLACYNGALVL-ANGNLSAPPISSHEVAIKEVVRIISETRTHFSQVSINLYSDTVWYVDR 124

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEP-----EGVSKVFFTCDSHEQLLPLEQAINARWGD 170
                 +  + A+ Q    E  LL         V K+     S E +  ++     +   
Sbjct: 125 LDEWVKK--EAAITQEVAQEADLLALVQSLQIPVHKLLLIGTSAE-IQKVKGYWEKQSLK 181

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
              +  S    LEV    VSK  AL  +A      L   +A GD  ND  M+  AG G  
Sbjct: 182 TSALYLSKDNYLEVTHREVSKEKALMELASYYNVPLAQTLAIGDNFNDLPMILKAGVGVA 241

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           M +A +R+++      V  +N D  V   L+K  LS
Sbjct: 242 MANAPRRVREQADA--VTLSNKDSGVAAALQKFVLS 275


>UniRef50_Q03GE4 Predicted hydrolase of the HAD superfamily n=2 Tax=Lactobacillales
           RepID=Q03GE4_PEDPA
          Length = 270

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 66/269 (24%), Positives = 114/269 (42%), Gaps = 9/269 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI---K 59
           +++A D+D TLL+ +  L P  K+ +       +  V  +GR    V    + L I    
Sbjct: 4   KLIAIDVDDTLLNSNIVLLPSTKDIIAKCLQNHLKVVLCSGRPLAGVKPFLNELGITADD 63

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            Y+IT NG+ +  + G +I +H L   +   +             + RD   + +     
Sbjct: 64  QYVITYNGSVIESVTGEVIASHELSNSVYRAMDEFSRKYHVAYNVLDRDSNIYTSNLEVN 123

Query: 120 EMRFFK--EAVFQYALYEPGLLEPE-GVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                +  E      +  P  L  +  ++K  F  ++ E L  +E+A++A + D+  V  
Sbjct: 124 RFTVVQAWENKAGLLIKTPDQLPADFTITKGIFVGETAE-LNQVEEAVHAAFDDQCYVVR 182

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           +    LEVM   V+KG AL+ +++KLG   ++ IAFGD  ND  M    G    M +   
Sbjct: 183 AADNFLEVMHKNVNKGAALKTLSEKLGIHPEEIIAFGDEQNDIPMFDFVGTAVAMENGSD 242

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             K       +  +N  D + + L KL  
Sbjct: 243 LAKSHAD--MITSSNDADGIKNALEKLIF 269


>UniRef50_C5RDT1 Cof-like hydrolase n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RDT1_CLOCL
          Length = 314

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 120/279 (43%), Gaps = 19/279 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGT+L+  H L+   K+ LK    +G++ V  +GR   D     + L + S 
Sbjct: 34  YKMICVDIDGTILNDKHKLTEDTKKALKEAHDKGLHVVICSGRLFSDAEYYSNLLGVNSS 93

Query: 62  MITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++ SNG  + D      IF   L ++  S L  + + + +I  + Y  D+ + +  +   
Sbjct: 94  IVGSNGTIIKDKKNDEFIFKKILGKNTCSKLLKIFSKH-NIKASFYTTDKVYSSNFKFTL 152

Query: 121 MRFFKEAV-------------FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
           + F  + +              +    +      + + K   T    ++L  L++ +   
Sbjct: 153 ILFLGKLIGVVSRNTKLKYIFNKKQWQQMIDTSVDNIYKCEVTVKDIDKLNALKKELKQL 212

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
               + +       +E+ + G++KG A++ + K      ++ I  GD  ND  M+  AG 
Sbjct: 213 --HDIELVNQAADNIEISSKGITKGSAVKFLTKYYNIKKEEVITIGDSGNDLPMIEYAGL 270

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           G  MG+A + +K+      +  +N D  V   + +  L+
Sbjct: 271 GVAMGNAFEDVKERAD--YITASNNDSGVAKVINEFVLT 307


>UniRef50_D0BJQ5 Cof family protein n=2 Tax=Granulicatella RepID=D0BJQ5_9LACT
          Length = 271

 Score =  221 bits (564), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 63/267 (23%), Positives = 115/267 (43%), Gaps = 8/267 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGT L+     +P   +TL  LT  G      TGR +     + + L +   +
Sbjct: 4   KLIALDLDGTTLNGQSEFNPITIQTLHRLTELGHKIAIVTGRPYRSSKHLYEELGLGGPL 63

Query: 63  ITSNGARVH---DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
           +  NGA  H   D +    F   LD +I  D+     +       V      +       
Sbjct: 64  VNFNGALCHIPNDENWQGEFHVTLDEEIVFDMLDFHKELECDYFMVEGKHHLYATIENIP 123

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF--S 177
           +  ++ +      L +   L  +  +   F+  S E+   +++ I  R+G  ++V     
Sbjct: 124 DSPYYPKDQQPILLQKDTQLLEKPTAITVFS--SIEKQPFIKEKIKQRYGHTIDVRTWGG 181

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
            + CLE++  G+ K   ++ +++  G   +D +AFGD  ND EM+  AG G  M +A   
Sbjct: 182 DMPCLEIVTYGIDKSTGIQHLSRYYGIPTEDVLAFGDEDNDLEMIEFAGHGVAMNNAIDS 241

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLY 264
           LK +  ++  +  +  D + HYL   +
Sbjct: 242 LKAIADDITPLP-HDQDGLAHYLMNYF 267


>UniRef50_C4FWW1 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FWW1_9FIRM
          Length = 275

 Score =  220 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 67/277 (24%), Positives = 121/277 (43%), Gaps = 17/277 (6%)

Query: 1   MYQ-------VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIR 53
           M +       ++A DLDGT L+    LSPY  + L+ +   G   V ATGR + +  Q  
Sbjct: 1   MIRRISMQAYLIAIDLDGTTLNNQSQLSPYTIQVLQQVRDMGHLVVIATGRPYRNSQQFY 60

Query: 54  DNLEIKSYMITSNGARVH---DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDE 110
             ++ ++ ++  NGA  H     +    +   + R++A  +     D    +        
Sbjct: 61  KAIDPQAPILNLNGAYGHYPGRPNWQARYEAEVPRELALKIMDQSRDLGVSLVCAEGPGY 120

Query: 111 WFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVS-KVFFTCDSHEQLLPLEQAINARWG 169
            F++ +   +  FF+       L  P  L     S  VF T ++ E +  L   +   +G
Sbjct: 121 VFVSSYDIPDSPFFQVDPNDLTLMTPESLTFGPTSLSVFSTAETQESIKKL---LLKEYG 177

Query: 170 DRVNVSFSTLT--CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
            +V++         LEV+  GV+K + ++ +A+         +AFGD  ND  M++ AG+
Sbjct: 178 QQVDIDTWGGNLPFLEVVQKGVNKAYGIDRLAQFYHIPNSHIMAFGDQHNDLSMIAYAGR 237

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G  M +A + LK +  ++    TN  D +  YL + +
Sbjct: 238 GVAMANAIEPLKAIANDITSY-TNDQDGLARYLVEFF 273


>UniRef50_A8VQS9 Type III restriction enzyme, res subunit n=1 Tax=Bacillus
           selenitireducens MLS10 RepID=A8VQS9_9BACI
          Length = 262

 Score =  220 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 73/266 (27%), Positives = 115/266 (43%), Gaps = 13/266 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + V  D+DGTLL+PD+ +S   K+ +  L  +G+    ATGR           L + + 
Sbjct: 3   IRAVFLDMDGTLLNPDNRISGRNKDAVLQLVNQGVKVFLATGRQFEITRPYHRQLGLTTP 62

Query: 62  MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           MI  NGA V D      ++  N+   I  + F  + + P     ++  D  F+ R   E 
Sbjct: 63  MICLNGAAVCDSFSAFPVYTKNV--HIKREAFHNIAEEPQCNAIIHTTDGTFVKRPSAET 120

Query: 121 MRFFKEAVFQY-ALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            R+ +E+  +   +     L P  V K    C       P EQA  AR+ D+ +V     
Sbjct: 121 RRWEQESGKKTRYMTNLRQLPPLPVLKYSIQC-----AHPYEQA-AARFQDQASVIQ-WE 173

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
              E++A   SK  A + + +  G    + +A GDG ND E+L  AG G  MG+A   +K
Sbjct: 174 NGFELVAPDTSKWAAAKNLIRAYGIRKDEVLAIGDGPNDIELLQYAGTGVAMGNASDSVK 233

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
                  V   +  D V  Y+ +  +
Sbjct: 234 AAAD--FVTMGHEKDGVADYIERFLI 257


>UniRef50_Q5WEW5 HAD superfamily hydrolase n=1 Tax=Bacillus clausii KSM-K16
           RepID=Q5WEW5_BACSK
          Length = 269

 Score =  220 bits (563), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 69/272 (25%), Positives = 107/272 (39%), Gaps = 13/272 (4%)

Query: 1   MYQ--VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI 58
           M +  ++A DLDGTLL  +  +SP  K  L     +G     ATGR +    +    L++
Sbjct: 1   MAKRHLIALDLDGTLLLKNQEISPRTKTALMKAKEKGHVIAIATGRPYRASKRYYQELQL 60

Query: 59  KSYMITSNGARVH---DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
            + +I  NGA VH   D     I   ++    + +L             V   D ++M +
Sbjct: 61  TTPIINFNGASVHHPLDAHYPRILE-SIPLAYSKELIKRCETIGVFNMMVEIGDTFYMKK 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                  F  + V      E   L  E  + +    +   + + +      + G    + 
Sbjct: 120 QAGFFAEFLTDGVEPAGTGELHALVKEAPTAILI--EPKPEKVNVLHDTLQQTGTETTLQ 177

Query: 176 F---STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
                    LE+    V+K  ALE +A   G    + IAFGD  ND EM+  AG G  MG
Sbjct: 178 RWWKGETRILEIAPRNVTKATALERIANDYGIEQGNIIAFGDEENDYEMIEYAGHGVAMG 237

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A   +K +     V  TN  D +  YL K+ 
Sbjct: 238 NAIDEIKAVADC--VTETNEKDGIACYLEKVL 267


>UniRef50_B0MA46 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MA46_9FIRM
          Length = 277

 Score =  220 bits (562), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 64/277 (23%), Positives = 111/277 (40%), Gaps = 17/277 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A D+DGTLL+    ++ +  E L+    RGI  V ATGR    + +    L+   Y
Sbjct: 6   IKLIAMDMDGTLLTSSKEITEHTIEVLEAAMDRGIQIVPATGRSVNGLPKKLTALKRMRY 65

Query: 62  MITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            I SNGARV+DL     I+ +  + D    L   V        ++ +D E +  +   + 
Sbjct: 66  CILSNGARVYDLHKKKSIYKNQFETDQVLKLLEDVRPY-HAFRSIAKDGEVYCYKEELDR 124

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVS-----------KVFFTCDSHEQLLPLEQAINARWG 169
           +  F    +   +        E +            K+    +  E+     + +     
Sbjct: 125 LGSFHLGEYSEEMIHASRTPVEDLKDYIIQEGGTSEKMTLFFEDQEERAKARKELTE--S 182

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
               V  S    LE+     +KG AL  + + L    ++ +A GD  ND EM+  AG G 
Sbjct: 183 GLYTVVASLKNNLEISLDSCNKGDALAHLMEHLDLKKENVMACGDAENDYEMILAAGIGV 242

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +M +    +K +     +   +  D V   + KL L+
Sbjct: 243 VMENGSDDMKAIAD--YITDDHNRDGVAKAIEKLVLN 277


>UniRef50_C3RM99 Hydrolase n=3 Tax=Bacteria RepID=C3RM99_9MOLU
          Length = 276

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 68/274 (24%), Positives = 116/274 (42%), Gaps = 11/274 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTAR-GINFVFATGRHHVDVGQIRDNLEIKS 60
           Y+++A DLD TLL+ +H +       +K      G+ FV ATGR  + +      L++  
Sbjct: 3   YKLIACDLDETLLNDEHLVGAKNVAAIKRAREEYGVKFVPATGRGFMQIQPELKELQLYD 62

Query: 61  ----YMITSNG-ARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I+ NG A   + +  +I    L+     ++F     N D+  +VY  D  ++  
Sbjct: 63  LEGEYVISFNGGALTENKNNRIIEFKGLEFSKMKEIFE-AGLNFDVCIHVYTPDNLYVFN 121

Query: 116 HRPEEMRFFKEAVFQ---YALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
               E +  K    +     +     L+   +SK+ +       L+ LE+ +        
Sbjct: 122 LSESERQRIKNQKLEAVYPEVNSVDFLKDTPISKILYQNVDVPYLMSLEEGLKPITDGHC 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            VS+S+   +E  A GV KG  L  +A KLG ++++ IA GD  ND  ML +AG      
Sbjct: 182 AVSYSSNRYMEFNALGVDKGQGLIDLANKLGIAIEETIAVGDNYNDMAMLKVAGLSVAAN 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +A   +K           N +  V   + K   +
Sbjct: 242 NAVDDVKAACDY-TTNANNNEGVVAELIEKFIFN 274


>UniRef50_Q03FP9 Predicted hydrolase of the HAD superfamily n=28 Tax=Lactobacillales
           RepID=Q03FP9_PEDPA
          Length = 270

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 69/268 (25%), Positives = 113/268 (42%), Gaps = 11/268 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++  DLDGT L+    LSP   +T+K  TA G      TGR +     I D L +K+ M
Sbjct: 4   KLITLDLDGTTLNSSSQLSPQTIKTIKNATAAGHIVSIVTGRPYRMARDIYDELSLKTPM 63

Query: 63  ITSNGARVHDL----DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
              NGA  H      DG   ++  +++ +  DL    +D    +  V   D +F +   P
Sbjct: 64  ANFNGALTHIPHQKWDGE--YSRTINKAVVYDLMKHKDDYGIQLLAVESKDSFFADHAAP 121

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV-SFS 177
               FF   +    +     L     S              ++  +   +G+ + V  + 
Sbjct: 122 ASFEFFPHEISNDQILTEKTLRTNPTSITILV--EPNSAQKVKNQLLHYYGEYITVGVWG 179

Query: 178 TLTC-LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
                LE+++ G+ K  A+  +A       +D IAFGD  NDAEML   G+G  M +A  
Sbjct: 180 GPQSVLEIVSKGIQKAKAVAYLADYYHIDRRDTIAFGDEHNDAEMLDYVGRGVAMKNATD 239

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ++K +  ++     N +D V  YL +  
Sbjct: 240 QIKGIANDITEFD-NTEDGVAKYLNEYL 266


>UniRef50_B9DIS6 Predicted hydrolases of the HAD superfamily n=61 Tax=Bacillales
           RepID=B9DIS6_STACT
          Length = 281

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 60/265 (22%), Positives = 110/265 (41%), Gaps = 7/265 (2%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++  DLDGTLL+    +SPY  + L+ L  +G   + ATGR         + L++ + ++
Sbjct: 5   LICLDLDGTLLNDKKEISPYTLKVLEKLKEQGHYIMIATGRPFRASKPYYEQLKLNTPIV 64

Query: 64  TSNGARVHDLD--GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
             NGA VH+     + +    LD D+A+ +   +             D  +++       
Sbjct: 65  NFNGAFVHNPTDPDSPVIHETLDPDLATSIIESLQKMQVKNIIAEVKDHVYIDNFDQHLF 124

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
             F     +    +      E  + +    D    +  ++Q ++  + + +         
Sbjct: 125 DGFSMGNPKIETGDIVNQLKEPPTSILIEADEV-MIPRVKQMLSRFYAESIEHRRWGAPF 183

Query: 182 --LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +E++  G+SK   +++V  +LG      IAFGD  ND EM+  A  G  M +    LK
Sbjct: 184 PVIEIVKRGISKARGIDSVKDELGVDRNHIIAFGDEDNDTEMIKYAKHGIAMENGLDELK 243

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
            +    EV  +N DD +  YL   +
Sbjct: 244 HIAN--EVTYSNNDDGIGRYLNDFF 266


>UniRef50_C8P0W5 Phosphatase YidA n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414
           RepID=C8P0W5_ERYRH
          Length = 261

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 71/265 (26%), Positives = 115/265 (43%), Gaps = 8/265 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVD-VGQIRDNLEIK 59
           M +++A+D+DGTLL  DH L+P  +ET+  L  +GI F  ATGR     V  I D  E+ 
Sbjct: 1   MIKLIATDMDGTLLDADHALTPSMRETILKLRQKGIKFGVATGRPMDSAVFGIPDIAELF 60

Query: 60  SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            + I  NG  V+D  DG +     L  D+  ++             +    + +      
Sbjct: 61  DFAICDNGGFVYDFADGEIHEQFPLSGDLIREILDTFMPMGGNPV-LTGPGKLYTQFEDF 119

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
             +        +Y      +L+     K+ F+ +  E L  +E  ++     R    +S 
Sbjct: 120 YNIEVRTHIDLEYVDVRSKVLDSHA--KIIFSGEP-ETLARIEAYVHENPDPRYVAFYSQ 176

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              +E M   ++K   L+    K G ++ + + FGD  ND  M+  AG G  M +A Q +
Sbjct: 177 KELIEFMDPRINKMVGLQYYMDKYGITVDEIMTFGDNNNDLHMIEDAGHGVAMENATQAV 236

Query: 239 KDLHPELEVIGTNADDAVPHYLRKL 263
           KD+     V G N +D V  YL + 
Sbjct: 237 KDVADA--VCGFNHEDGVKRYLDQY 259


>UniRef50_B9RS16 Phosphatase yidA, putative n=1 Tax=Ricinus communis
           RepID=B9RS16_RICCO
          Length = 595

 Score =  220 bits (562), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 67/270 (24%), Positives = 116/270 (42%), Gaps = 13/270 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--K 59
           ++ +  D+DGTLL+    +S    + LK   +R +  V ATG+    V  I   +++  K
Sbjct: 323 FRYIFCDMDGTLLNSKSQISSTNAKALKEALSRDVKVVIATGKARPAVISILKMVDLAGK 382

Query: 60  SYMITS-------NGARVHDLDGNLIFAHNLDRDIASD--LFGVVNDNPDIITNVYRDDE 110
             +I+         G  V+   G  IF  NLD+ +  +  L+   +  P I  +  R   
Sbjct: 383 DGVISEFSPGVFLQGLLVYGRQGREIFRSNLDQSVCREACLYSWEHKVPLIAFSNDRCLT 442

Query: 111 WFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            F +         ++E   +       LL    + K+ F   +      L    +   GD
Sbjct: 443 LFDHPLVDSLHTIYREPKAEIMPSVEHLLAASDIQKMIFLDTAEGVATSLRPYWSEAMGD 502

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           R NV  +    LE++  G SKG  ++ +   LG + K+ +A GDG ND EML +A  G  
Sbjct: 503 RANVVQAVPDMLEIVPRGTSKGTGVKMLLDHLGITAKEIMAIGDGENDIEMLELASLGIA 562

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
           + +  ++ K +   + V  +N +D V   +
Sbjct: 563 LSNGAEKTKAVADVVGV--SNDEDGVADAI 590


>UniRef50_B9Z762 Cof-like hydrolase n=1 Tax=Lutiella nitroferrum 2002
           RepID=B9Z762_9NEIS
          Length = 268

 Score =  220 bits (561), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 95/264 (35%), Positives = 135/264 (51%), Gaps = 11/264 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY  +ASDLDGTLL    T++P+   TL+   ARG++ + ATGRH  DV  +   LE+  
Sbjct: 1   MYAAIASDLDGTLLDARETITPFTAATLRAAAARGVHLIIATGRHVRDVQHLTAALELPI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII----TNVYRDDEWFMNRH 116
            +ITSNGARVH  DG L+ A ++  +    L       PD+      ++Y D+      H
Sbjct: 61  SLITSNGARVHGSDGALLHADDVPAEHVRALL-----QPDLAHGTRLSLYLDEGGLCCLH 115

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                R   E  F     +       GV+K+ +T     +L  +E AI  R+G  + +++
Sbjct: 116 DGYVHR-DAETGFSQQCDDLSQHPGHGVAKLMYTAPPT-RLAEIEAAIRQRFGSALALTY 173

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LEVMA GVSKG AL  +  +LG + + C AFGDG+ND EML   G    M +A  
Sbjct: 174 SRPDYLEVMAPGVSKGRALTRLLARLGVAPERCAAFGDGLNDVEMLQSVGHPFRMANASP 233

Query: 237 RLKDLHPELEVIGTNADDAVPHYL 260
           RL  L PE+   G + +  V   +
Sbjct: 234 RLSALLPEVAEAGHHDEAGVARQI 257


>UniRef50_C4L8T6 Cof-like hydrolase n=1 Tax=Tolumonas auensis DSM 9187
           RepID=C4L8T6_TOLAT
          Length = 273

 Score =  220 bits (561), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 65/275 (23%), Positives = 109/275 (39%), Gaps = 16/275 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
             V+A D+DGTLL+ DHT++    +TL+    +GI  +  TGRHH+    +   L +++ 
Sbjct: 4   IAVIALDMDGTLLTSDHTVTRETVDTLRQARDKGIEVILVTGRHHMMACPVHHQLALETP 63

Query: 62  MITSNGARVHDLDGNLIFA-HNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I SNGA + D     I A + L       L  ++ ++  +    +  D           
Sbjct: 64  LICSNGAYIFDFQAKRITAGNPLHDWQWQQLLPLI-ESLQLDVICHFSDGIGHQPDNVHI 122

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVS----------KVFFTCDSHEQLLPLEQAINARWGD 170
            +           + P  +E   ++          K+     +   +     A+    G 
Sbjct: 123 AKIKNHLSTLPPEHYPHFIEHSSLATLCNTHVPLWKIEIAHATPAAIDAFIDALPD--GL 180

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            +    +    LE++  G SKG+ L       G +L   IAFGD  ND  M    G G  
Sbjct: 181 AITHDRTAPNGLEIVNTGSSKGNRLAEWVAGKGIALDQVIAFGDNHNDISMFQQVGLGVA 240

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           MG+A   ++       V  +N D  +   LR+  L
Sbjct: 241 MGNATPEIQQYAD--FVTCSNDDSGIASALRRWVL 273


>UniRef50_A7VVP1 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VVP1_9CLOT
          Length = 304

 Score =  220 bits (561), Expect = 4e-56,   Method: Composition-based stats.
 Identities = 65/266 (24%), Positives = 114/266 (42%), Gaps = 5/266 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASDLDGTLL+    L       +  L   G+ F+ A+GR +  + +       + 
Sbjct: 39  MIRLIASDLDGTLLNSQRQLPKDFFSVIDRLNQLGVLFIAASGRSYPTLRRDFAPHSDEL 98

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN-RHRPE 119
             I+ NGAR+ +  G ++    +   + S +       P++   +  D   + N +  P 
Sbjct: 99  CFISDNGARIAE-HGKILQKDPIPPQVVSQVLETCASLPEVKPVLTSDRGTYANTKGEPW 157

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
                      Y   +      E   K+   CD    +    + +     D  ++  S  
Sbjct: 158 FHDCILAYFDNYQQVDDLSSVHEDFYKISL-CDRAGAVKNSFRLMPQSLRDSADLQVSGF 216

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             L+VM  GV KG AL+A  K+ G S ++ + FGD  ND++ML  A    +M +A++ +K
Sbjct: 217 IWLDVMKKGVDKGKALQAFQKRYGISKEETMVFGDFYNDSQMLLQAKYSFVMENANEDMK 276

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
                  +  +N DD V   ++K  L
Sbjct: 277 PFGN--FIAPSNDDDGVMRMIKKYVL 300


>UniRef50_D1AM09 Cof-like hydrolase n=6 Tax=Bacteria RepID=D1AM09_SEBTE
          Length = 269

 Score =  220 bits (561), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 65/265 (24%), Positives = 110/265 (41%), Gaps = 5/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLS-PYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
            ++VA D+DGT +  D+T      +  L  +   G +FV A+G  +  +  +      + 
Sbjct: 5   IKMVAVDIDGTFVHSDYTYDILRFQRILSRMNDAGCHFVVASGNQYYQLRDLFPGYYNEL 64

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             +  NGA V D    LIF  N+ +D    +  V  D P+I   +   +  +  R    +
Sbjct: 65  SFVAENGAFVKDGQ-ELIFTANIPKDTVDAVIDVCRDYPEISNVLCGVESAYCQRGTVSQ 123

Query: 121 MRFFKEAVFQYAL-YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
             F   A++ + L +     E +     F      E+          R   +V  + S  
Sbjct: 124 EFFDLTAIYYHRLKWVDDFKEVKDQILKFAPTVPEEKTYFYYDIFCERLKGKVEPTTSGH 183

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             ++++  G  K   L+ + K+ G S + C AFGDG ND EML+  G    M +A   +K
Sbjct: 184 GSIDLIVPGCHKASGLKRLTKRWGISPEQCAAFGDGGNDIEMLNYCGYSYAMENASDSVK 243

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
                  V  +N +D V   L +L+
Sbjct: 244 AAAK--FVCPSNEEDGVLATLEELF 266


>UniRef50_D1CC39 Cof-like hydrolase n=1 Tax=Thermobaculum terrenum ATCC BAA-798
           RepID=D1CC39_THET1
          Length = 285

 Score =  220 bits (561), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 64/276 (23%), Positives = 113/276 (40%), Gaps = 16/276 (5%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A DLDGTLL     + P  KE ++     G+    ATGR      +I + + I   ++
Sbjct: 1   MIALDLDGTLLDSHGRVRPRVKEAVRKAIDLGVIVTIATGRRLHFAQKIAEEIGIDVPLV 60

Query: 64  TSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPD---IITNVYRDDEWFM---NRH 116
              G  + D   G +I+   +   +  +   +V +      +  +             + 
Sbjct: 61  LHGGTLIQDSATGEVIYEDVMSPSLVREAVELVVNYGHQPVLFVSPSAGGGLLAGPPEKD 120

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                ++         L    L   E V  V+   + H+ L PL +A+  R   +V +  
Sbjct: 121 SVLASQYLNSQRNIKRLPYEDLANAEHVLSVWVI-EDHDVLGPLYEAMVKRPYYKVLLWE 179

Query: 177 STL------TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
                      L+++  G SK  AL  +A   G S+ + +A GD +ND EM+  AG G  
Sbjct: 180 PEPDKPDTGYLLDILNVGASKAKALRHLAASYGISMDEVMAIGDQINDLEMMEAAGLGVA 239

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           MG+A   +++L     V+ +N +D V   + +  LS
Sbjct: 240 MGNAISPVRELANA--VVSSNDEDGVAEAIERFVLS 273


>UniRef50_C0XNN9 HAD family hydrolase n=3 Tax=Corynebacterium RepID=C0XNN9_9CORY
          Length = 274

 Score =  219 bits (560), Expect = 6e-56,   Method: Composition-based stats.
 Identities = 64/273 (23%), Positives = 119/273 (43%), Gaps = 13/273 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ SD+DGT L+    ++P  ++ +      G +F  ATGR H  +  + D L I    
Sbjct: 4   RLIISDIDGTFLTSAGRVTPRLRDVVMRAVRSGAHFGLATGRPHRWLMPVLDQLPISPVC 63

Query: 63  ITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVND--NPDIITNVYRDDEWFMNRHRPE 119
           + +NGA  +D     ++ A  LD ++ + +   V+    P  +   Y  +    +   PE
Sbjct: 64  VCANGAVTYDPARDEVLRAFELDSELMAQVVADVDAVFRPLGVRWGYGVERVGQSALDPE 123

Query: 120 EMRFFKEAVFQYALYEPGL-------LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
           +  F     +    ++P         L     +K+   C         +           
Sbjct: 124 DEVFLVTPDYNPDAWDPRFGVAPVSELVSVPAAKLLVRCAEMHSAEMFDLIAPVIDTSEA 183

Query: 173 NVSFSTL-TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           ++++S     +E+ + GV+K   + A+A   G S +D +AFGD  ND EML+ +G G  M
Sbjct: 184 HITYSMDEGLIEISSPGVTKATGVSALASHYGVSAEDVVAFGDMPNDCEMLAWSGLGVAM 243

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G+A+  + D+     V  +N +D V   L + +
Sbjct: 244 GNANPVVLDVAD--TVTVSNDEDGVAKVLEQWF 274


>UniRef50_C5RAP3 Haloacid dehalogenase (HAD) superfamily hydrolase n=1 Tax=Weissella
           paramesenteroides ATCC 33313 RepID=C5RAP3_WEIPA
          Length = 278

 Score =  219 bits (560), Expect = 6e-56,   Method: Composition-based stats.
 Identities = 63/268 (23%), Positives = 105/268 (39%), Gaps = 6/268 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M   +A DLD TLL+    +S   +  LK L   G   V  TGR    + ++   LE+  
Sbjct: 11  MITTIALDLDNTLLNSAKEISEENERVLKQLHKMGKRIVLCTGRPIQGIQKLLTQLELFE 70

Query: 59  -KSYMITSNGARVHDLDGNLIFAHN-LDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NG  +       I A   + +   + L+         I  +  D  + +   
Sbjct: 71  PTDYAITFNGGLIQHNQTQRILAQTTISKHEVAALYQDAQKRHYPIDVIGADQVYSLITL 130

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                     AV  +       L  +            E +  + + + A   D +++  
Sbjct: 131 GKSAYESTMGAVLPFTDVSFDDLPVDQTFGKAVCAAPAEVVQRVRKEMPAELNDLLHIVP 190

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE +   V+K   L  +    G +L + + FGD  ND EM++ AG G  MG+A  
Sbjct: 191 SRAELLEFLPNNVNKARGLTQLMAHFGETLDNAMTFGDEENDFEMIAQAGIGVAMGNAIP 250

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ++K +     +  TN +D V  YL++ +
Sbjct: 251 QIKQVAKAETL--TNNEDGVAAYLKQYF 276


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A0KR21 Hydrolase, Cof family n=3 Tax=Aeromonadaceae Rep...   318   1e-85
UniRef50_P27848 Uncharacterized protein yigL n=168 Tax=Bacteria ...   316   4e-85
UniRef50_A1HSX6 Cof-like hydrolase n=1 Tax=Thermosinus carboxydi...   300   3e-80
UniRef50_C6CW76 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CW...   295   1e-78
UniRef50_Q7MQB3 Predicted hydrolase n=59 Tax=Gammaproteobacteria...   293   4e-78
UniRef50_C4LAX9 Cof-like hydrolase n=28 Tax=Bacteria RepID=C4LAX...   292   1e-77
UniRef50_P54947 Uncharacterized protein yxeH n=10 Tax=Firmicutes...   291   1e-77
UniRef50_C9KQV0 HAD-superfamily hydrolase, subfamily IIB n=2 Tax...   291   2e-77
UniRef50_Q0B097 Putative uncharacterized protein n=1 Tax=Syntrop...   290   3e-77
UniRef50_B8DEX6 Phosphatase YidA n=17 Tax=Listeria RepID=B8DEX6_...   290   4e-77
UniRef50_D0BNB6 Phosphatase YidA n=2 Tax=Granulicatella RepID=D0...   289   9e-77
UniRef50_Q2RLU7 HAD-superfamily hydrolase subfamily IIB n=1 Tax=...   288   1e-76
UniRef50_B8I4P5 Cof-like hydrolase n=2 Tax=Clostridium RepID=B8I...   287   4e-76
UniRef50_C6JR95 Hydrolase n=2 Tax=Fusobacterium RepID=C6JR95_FUSVA    287   4e-76
UniRef50_Q38V42 Hydrolase, haloacid dehalogenase family n=2 Tax=...   286   5e-76
UniRef50_P0A8Y6 Phosphatase yidA n=235 Tax=cellular organisms Re...   286   6e-76
UniRef50_B0K874 Cof-like hydrolase n=10 Tax=Thermoanaerobacterac...   285   8e-76
UniRef50_A8U9P8 Hydrolase, haloacid dehalogenase-like family pro...   284   2e-75
UniRef50_Q5XD45 Putative hydrolase M6_Spy0533 n=25 Tax=Streptoco...   284   3e-75
UniRef50_C3WN06 Hydrolase n=12 Tax=Fusobacterium RepID=C3WN06_9FUSO   283   4e-75
UniRef50_C3WDD5 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC ...   282   7e-75
UniRef50_C4FT61 Putative uncharacterized protein n=1 Tax=Catonel...   282   8e-75
UniRef50_Q0SVE4 HAD hydrolase, IIB family n=17 Tax=Clostridium R...   282   1e-74
UniRef50_C2KV90 HAD superfamily hydrolase n=1 Tax=Oribacterium s...   282   1e-74
UniRef50_C6P8T7 Cof-like hydrolase n=1 Tax=Thermoanaerobacterium...   280   3e-74
UniRef50_B0K375 Cof-like hydrolase n=11 Tax=Thermoanaerobacteral...   280   3e-74
UniRef50_C2LH85 HAD superfamily hydrolase n=3 Tax=Enterobacteria...   279   6e-74
UniRef50_Q3AFE4 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...   279   6e-74
UniRef50_C6AQ91 Cof protein n=4 Tax=Bacteria RepID=C6AQ91_AGGAN       279   8e-74
UniRef50_Q04GT8 Predicted hydrolase of the HAD superfamily n=2 T...   279   8e-74
UniRef50_A4XJ23 Cof-like hydrolase n=2 Tax=Clostridia RepID=A4XJ...   278   2e-73
UniRef50_Q5DYX0 Predicted hydrolase n=65 Tax=Bacteria RepID=Q5DY...   277   2e-73
UniRef50_C2H930 Haloacid dehalogenase (HAD) superfamily hydrolas...   277   2e-73
UniRef50_D1AJW8 Cof-like hydrolase n=1 Tax=Sebaldella termitidis...   277   2e-73
UniRef50_Q891C8 Hydrolase (HAD superfamily) n=3 Tax=Bacteria Rep...   277   3e-73
UniRef50_B8FYX3 Cof-like hydrolase n=2 Tax=Desulfitobacterium ha...   276   5e-73
UniRef50_A8GAR8 HMP-PP phosphatase n=39 Tax=Enterobacteriaceae R...   275   8e-73
UniRef50_UPI0001C365F0 putative haloacid dehalogenase-like hydro...   275   9e-73
UniRef50_C8P4G9 Cof family protein n=1 Tax=Lactobacillus antri D...   275   9e-73
UniRef50_C9AY54 HAD-superfamily hydrolase n=4 Tax=Enterococcus R...   275   1e-72
UniRef50_B8CYJ2 Cof-like hydrolase n=1 Tax=Halothermothrix oreni...   275   1e-72
UniRef50_C9XLD9 Putative hydrolase n=7 Tax=Clostridium difficile...   275   1e-72
UniRef50_A8MEY7 Cof-like hydrolase n=2 Tax=Alkaliphilus RepID=A8...   275   1e-72
UniRef50_A6LB32 Haloacid dehalogenase-like hydrolase n=23 Tax=Ba...   275   1e-72
UniRef50_B0ADP8 Putative uncharacterized protein n=1 Tax=Clostri...   274   2e-72
UniRef50_Q03T33 Predicted hydrolase of the HAD superfamily n=9 T...   274   2e-72
UniRef50_C1QE38 HAD-superfamily hydrolase, subfamily IIB n=1 Tax...   274   2e-72
UniRef50_A4BEF7 Hydrolase, haloacid dehalogenase-like family pro...   274   3e-72
UniRef50_Q2JQT8 HAD hydrolase, IIB family n=1 Tax=Synechococcus ...   273   4e-72
UniRef50_C9LAG7 HAD hydrolase, IIB family n=1 Tax=Blautia hansen...   273   4e-72
UniRef50_A0AEX0 Complete genome n=17 Tax=Listeria RepID=A0AEX0_L...   273   4e-72
UniRef50_Q897B3 Putative haloacid dehalogenase-like hydrolase n=...   272   7e-72
UniRef50_UPI0001BC341D haloacid dehalogenase-like hydrolase n=1 ...   272   9e-72
UniRef50_A6LB33 Haloacid dehalogenase-like hydrolase n=34 Tax=Ba...   270   3e-71
UniRef50_A6FJC9 Putative uncharacterized protein n=1 Tax=Moritel...   270   4e-71
UniRef50_D1PLJ0 Hydrolase n=1 Tax=Subdoligranulum variabile DSM ...   270   4e-71
UniRef50_C2EBE1 HAD superfamily hydrolase n=1 Tax=Lactobacillus ...   270   4e-71
UniRef50_Q8ENE7 Hypothetical conserved protein n=1 Tax=Oceanobac...   270   4e-71
UniRef50_B7HYF7 Hydrolase, haloacid dehalogenase-like family n=8...   269   8e-71
UniRef50_A1SVY5 Cof-like hydrolase n=4 Tax=Bacteria RepID=A1SVY5...   269   9e-71
UniRef50_C3K9U8 Putative haloacid dehalogenase-like hydrolase n=...   269   1e-70
UniRef50_C5WIM4 HAD superfamily hydrolase n=3 Tax=Streptococcus ...   269   1e-70
UniRef50_C1I280 HAD hydrolase n=1 Tax=Clostridium sp. 7_2_43FAA ...   268   1e-70
UniRef50_Q0TQ35 HAD hydrolase, IIB family n=9 Tax=Clostridium pe...   268   1e-70
UniRef50_C9XMM6 Putative hydrolase n=4 Tax=Clostridium difficile...   268   1e-70
UniRef50_A1V919 HAD hydrolase, IIB family n=56 Tax=Betaproteobac...   268   2e-70
UniRef50_C6PMT7 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...   267   2e-70
UniRef50_C5RAW2 HAD superfamily hydrolase n=1 Tax=Weissella para...   267   2e-70
UniRef50_C6IVB2 Predicted protein n=3 Tax=Bacillales RepID=C6IVB...   267   2e-70
UniRef50_B6XF55 Putative uncharacterized protein n=2 Tax=Provide...   267   3e-70
UniRef50_UPI000197CA00 hypothetical protein PretD1_00540 n=1 Tax...   267   4e-70
UniRef50_A6P2T9 Putative uncharacterized protein n=1 Tax=Bactero...   266   5e-70
UniRef50_C6VK79 HAD superfamily hydrolase n=17 Tax=Lactobacillus...   265   7e-70
UniRef50_C7HV82 HAD phosphatase superfamily protein n=1 Tax=Anae...   265   8e-70
UniRef50_B4SM39 Cof-like hydrolase n=4 Tax=Bacteria RepID=B4SM39...   265   8e-70
UniRef50_C9R7C9 Cof protein n=1 Tax=Aggregatibacter actinomycete...   265   1e-69
UniRef50_C6VMV1 HAD superfamily hydrolase n=10 Tax=Lactobacillal...   265   1e-69
UniRef50_A6LQL6 Cof-like hydrolase n=1 Tax=Clostridium beijerinc...   265   2e-69
UniRef50_D1XVB8 Cof-like hydrolase n=1 Tax=Prevotella bivia JCVI...   264   2e-69
UniRef50_C5NXD6 Phosphatase YidA n=1 Tax=Gemella haemolysans ATC...   264   2e-69
UniRef50_C2D902 HAD family hydrolase n=1 Tax=Atopobium vaginae D...   264   2e-69
UniRef50_B2A708 Cof-like hydrolase n=1 Tax=Natranaerobius thermo...   264   2e-69
UniRef50_C7TGI6 Hydrolase of the HAD superfamily n=9 Tax=Lactoba...   264   2e-69
UniRef50_C2BEV0 HAD superfamily hydrolase n=1 Tax=Anaerococcus l...   263   3e-69
UniRef50_P94592 Uncharacterized phosphatase ywpJ n=7 Tax=Bacilla...   263   3e-69
UniRef50_B0P090 Putative uncharacterized protein n=2 Tax=Clostri...   263   3e-69
UniRef50_C6PXU7 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...   263   4e-69
UniRef50_C5RPZ1 Cof-like hydrolase n=1 Tax=Clostridium cellulovo...   263   4e-69
UniRef50_C6CYC3 Cof-like hydrolase n=1 Tax=Paenibacillus sp. JDR...   263   4e-69
UniRef50_A8UBX5 Putative uncharacterized protein n=1 Tax=Carnoba...   263   4e-69
UniRef50_C7N949 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7...   263   4e-69
UniRef50_C9KQH1 HAD phosphatase family protein n=2 Tax=Clostridi...   263   4e-69
UniRef50_D0BK11 Cof family protein n=2 Tax=Granulicatella RepID=...   263   4e-69
UniRef50_B9CKY2 Phosphatase YidA n=1 Tax=Atopobium rimae ATCC 49...   263   5e-69
UniRef50_C3WDI3 Hydrolase n=2 Tax=Fusobacterium mortiferum ATCC ...   262   6e-69
UniRef50_A6BG65 Putative uncharacterized protein n=5 Tax=Clostri...   262   7e-69
UniRef50_A0Q2R8 Cof-like hydrolase n=1 Tax=Clostridium novyi NT ...   262   1e-68
UniRef50_B1L8F5 Cof-like hydrolase n=6 Tax=Thermotogaceae RepID=...   262   1e-68
UniRef50_A9KKJ5 Cof-like hydrolase n=3 Tax=Clostridiales RepID=A...   262   1e-68
UniRef50_A9H329 Cof-like hydrolase n=1 Tax=Gluconacetobacter dia...   261   1e-68
UniRef50_B9DT57 Putative haloacid dehalogenase-like hydrolase n=...   261   2e-68
UniRef50_C6JKA3 HAD-superfamily hydrolase subfamily IIB n=3 Tax=...   261   2e-68
UniRef50_Q030F1 Predicted hydrolase of the HAD superfamily n=34 ...   261   2e-68
UniRef50_C7RFK7 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7...   261   2e-68
UniRef50_B8DIC3 Hydrolase, Cof family n=18 Tax=Listeria RepID=B8...   261   2e-68
UniRef50_A5Z5X7 Putative uncharacterized protein n=1 Tax=Eubacte...   260   3e-68
UniRef50_Q1WS49 Hydrolase, HAD superfamily n=2 Tax=Lactobacillus...   260   3e-68
UniRef50_C2EN69 HAD family hydrolase n=7 Tax=Firmicutes RepID=C2...   260   3e-68
UniRef50_Q0STC6 HAD hydrolase, IIB family n=9 Tax=Clostridium pe...   260   3e-68
UniRef50_A8ST52 Putative uncharacterized protein n=2 Tax=Clostri...   260   3e-68
UniRef50_UPI0001C430CB Cof-like hydrolase n=1 Tax=Bacillus pseud...   260   3e-68
UniRef50_Q1JAD8 Hydrolase n=30 Tax=Streptococcus RepID=Q1JAD8_STRPB   260   3e-68
UniRef50_C6CZV3 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CZ...   260   4e-68
UniRef50_C7NEL2 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7...   260   4e-68
UniRef50_D2LWT0 Cof-like hydrolase n=1 Tax=Bacillus cellulosilyt...   260   5e-68
UniRef50_A6T5I9 HMP-PP phosphatase n=18 Tax=Bacteria RepID=COF_K...   259   6e-68
UniRef50_B9DRH4 Haloacid dehalogenase-like hydrolase n=11 Tax=St...   259   6e-68
UniRef50_B2IW20 Cof-like hydrolase n=18 Tax=Cyanobacteria RepID=...   259   7e-68
UniRef50_C2KAT0 Possible sugar-phosphatase n=1 Tax=Chryseobacter...   259   7e-68
UniRef50_Q7MFQ8 Predicted hydrolase n=24 Tax=Vibrionales RepID=Q...   259   8e-68
UniRef50_Q8KA73 Uncharacterized protein BUsg_029 n=5 Tax=Buchner...   259   8e-68
UniRef50_Q4D2M6 Haloacid dehalogenase-like hydrolase, putative n...   259   8e-68
UniRef50_UPI000196AEDD hypothetical protein CATMIT_00603 n=1 Tax...   258   9e-68
UniRef50_B0BRY2 Predicted hydrolases of the HAD superfamily n=7 ...   258   9e-68
UniRef50_B5CTA9 Putative uncharacterized protein n=4 Tax=Clostri...   258   1e-67
UniRef50_C5D2V8 Cof-like hydrolase n=3 Tax=Geobacillus RepID=C5D...   258   1e-67
UniRef50_C4V675 HAD superfamily hydrolase n=1 Tax=Selenomonas fl...   258   1e-67
UniRef50_B2GFE5 Hydrolase n=12 Tax=Lactobacillus RepID=B2GFE5_LACF3   258   2e-67
UniRef50_A5KNX9 Putative uncharacterized protein n=8 Tax=Clostri...   258   2e-67
UniRef50_C1P6V3 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36...   257   2e-67
UniRef50_Q1WSZ0 Hydrolase, HAD superfamily n=9 Tax=Lactobacillal...   257   2e-67
UniRef50_C9LXL5 HAD-superfamily hydrolase, family protein IIB n=...   257   2e-67
UniRef50_C2LPY8 HAD-superfamily hydrolase, subfamily IIB n=5 Tax...   257   3e-67
UniRef50_C0Z8L2 Putative uncharacterized protein n=1 Tax=Breviba...   257   3e-67
UniRef50_B0P1S7 Putative uncharacterized protein n=2 Tax=Clostri...   257   3e-67
UniRef50_Q0TU23 HAD-superfamily hydrolase, subfamily IIB n=7 Tax...   257   3e-67
UniRef50_P70947 Putative phosphatase yitU n=101 Tax=Firmicutes R...   257   4e-67
UniRef50_B0N4M8 Putative uncharacterized protein n=3 Tax=Bacteri...   256   5e-67
UniRef50_C7JF38 Hydrolase n=8 Tax=Acetobacter pasteurianus RepID...   256   5e-67
UniRef50_A4VVF4 Predicted hydrolase of the HAD superfamily n=38 ...   256   5e-67
UniRef50_C1P783 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36...   256   5e-67
UniRef50_Q97ES2 HAD superfamily hydrolase n=1 Tax=Clostridium ac...   256   6e-67
UniRef50_C0X6C9 HAD superfamily hydrolase n=22 Tax=Enterococcus ...   256   6e-67
UniRef50_C6JK34 Hydrolase n=2 Tax=Fusobacterium RepID=C6JK34_FUSVA    256   6e-67
UniRef50_C6QV31 Cof-like hydrolase n=1 Tax=Geobacillus sp. Y4.1M...   256   7e-67
UniRef50_P44771 Uncharacterized protein HI0597 n=32 Tax=Pasteure...   256   7e-67
UniRef50_Q5WG82 HAD superfamily hydrolase n=1 Tax=Bacillus claus...   255   1e-66
UniRef50_C1I4C1 HAD superfamily hydrolase n=1 Tax=Clostridium sp...   255   1e-66
UniRef50_P44447 Uncharacterized protein HI0003 n=16 Tax=Haemophi...   255   1e-66
UniRef50_C3WAR4 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC ...   255   1e-66
UniRef50_Q03GE4 Predicted hydrolase of the HAD superfamily n=2 T...   255   1e-66
UniRef50_D0BM40 Cof family protein n=2 Tax=Granulicatella RepID=...   255   2e-66
UniRef50_Q042H4 Predicted hydrolase of the HAD superfamily n=11 ...   254   2e-66
UniRef50_B9EBT4 Putative uncharacterized protein n=1 Tax=Macroco...   254   2e-66
UniRef50_A9VQD5 Cof-like hydrolase n=72 Tax=Bacillus RepID=A9VQD...   254   2e-66
UniRef50_A5CYL3 Predicted hydrolase n=5 Tax=Clostridia RepID=A5C...   253   3e-66
UniRef50_Q8ELU0 Hypothetical conserved protein n=1 Tax=Oceanobac...   253   3e-66
UniRef50_B2S2N8 Putative uncharacterized protein n=1 Tax=Trepone...   253   4e-66
UniRef50_UPI000196CFC2 hypothetical protein CATMIT_02842 n=1 Tax...   253   4e-66
UniRef50_C5NUB3 Hydrolase n=3 Tax=Firmicutes RepID=C5NUB3_9BACL       253   5e-66
UniRef50_D0A841 Haloacid dehalogenase-like hydrolase, putative n...   253   5e-66
UniRef50_D2RIN9 Cof-like hydrolase n=2 Tax=Acidaminococcus RepID...   253   6e-66
UniRef50_Q04BG8 Predicted hydrolase of the HAD superfamily n=13 ...   252   6e-66
UniRef50_Q737I7 Hydrolase, haloacid dehalogenase-like family n=6...   252   7e-66
UniRef50_C9RTQ8 Cof-like hydrolase n=4 Tax=Geobacillus RepID=C9R...   252   7e-66
UniRef50_C4FTB9 Putative uncharacterized protein n=1 Tax=Catonel...   252   7e-66
UniRef50_Q5WGE2 HAD superfamily hydrolase n=2 Tax=Bacillus RepID...   252   7e-66
UniRef50_A7VNH3 Putative uncharacterized protein n=1 Tax=Clostri...   252   8e-66
UniRef50_C6W4G6 Cof-like hydrolase n=1 Tax=Dyadobacter fermentan...   252   8e-66
UniRef50_Q4KBY5 Cof-like hydrolase family protein n=8 Tax=Pseudo...   252   1e-65
UniRef50_A7ZIK4 HMP-PP phosphatase n=87 Tax=Bacteria RepID=COF_E...   252   1e-65
UniRef50_C2M275 Sugar phosphatase SupH n=1 Tax=Capnocytophaga gi...   252   1e-65
UniRef50_B6FMU0 Putative uncharacterized protein n=1 Tax=Clostri...   252   1e-65
UniRef50_C4VRW0 Phosphatase YidA n=1 Tax=Lactobacillus gasseri 2...   251   2e-65
UniRef50_D1AMP5 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepI...   251   2e-65
UniRef50_C7XLV6 Putative uncharacterized protein n=1 Tax=Lactoba...   251   2e-65
UniRef50_Q184T9 Putative hydrolase n=7 Tax=Clostridium difficile...   251   2e-65
UniRef50_C0ZHG1 Putative uncharacterized protein n=1 Tax=Breviba...   251   2e-65
UniRef50_A5I530 HAD-superfamily hydrolase, subfamily IIB n=12 Ta...   250   2e-65
UniRef50_C5RDT1 Cof-like hydrolase n=1 Tax=Clostridium cellulovo...   250   2e-65
UniRef50_B1BZI7 Putative uncharacterized protein n=2 Tax=Clostri...   250   3e-65
UniRef50_C5RAP3 Haloacid dehalogenase (HAD) superfamily hydrolas...   250   3e-65
UniRef50_A3I239 Putative uncharacterized protein n=1 Tax=Algorip...   250   3e-65
UniRef50_Q042G1 Predicted hydrolase of the HAD superfamily n=8 T...   250   3e-65
UniRef50_B9DIS6 Predicted hydrolases of the HAD superfamily n=61...   250   3e-65
UniRef50_UPI0001C423D6 hypothetical protein BpOF4_15910 n=1 Tax=...   250   4e-65
UniRef50_Q2B1F0 Putative uncharacterized protein n=2 Tax=Bacillu...   250   4e-65
UniRef50_P42962 Uncharacterized protein ycsE n=9 Tax=Bacillus Re...   250   4e-65
UniRef50_C0R158 Putative hydrolase n=1 Tax=Brachyspira hyodysent...   250   5e-65
UniRef50_Q03PI8 Predicted hydrolase of the HAD superfamily n=14 ...   250   5e-65
UniRef50_A5FGB8 Cof-like hydrolase n=1 Tax=Flavobacterium johnso...   250   5e-65
UniRef50_C7RDZ8 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7...   249   6e-65
UniRef50_Q034C6 Predicted hydrolase of the HAD superfamily n=8 T...   249   6e-65
UniRef50_B6WB05 Putative uncharacterized protein n=1 Tax=Anaeroc...   249   6e-65
UniRef50_B7GIB3 Predicted hydrolase of the HAD superfamily n=3 T...   249   6e-65
UniRef50_P74365 Sll1524 protein n=1 Tax=Synechocystis sp. PCC 68...   249   7e-65
UniRef50_A1SZR3 Cof-like hydrolase n=2 Tax=Psychromonas RepID=A1...   249   7e-65
UniRef50_Q1WV35 Hydrolase, HAD superfamily n=2 Tax=Lactobacillus...   249   7e-65
UniRef50_Q3D5Y9 Hydrolase, haloacid dehalogenase-like family n=9...   248   1e-64
UniRef50_C0CY86 Putative uncharacterized protein n=3 Tax=Clostri...   248   1e-64
UniRef50_A4XJ10 Cof-like hydrolase n=2 Tax=Clostridia RepID=A4XJ...   248   1e-64
UniRef50_C6PUS4 Cof-like hydrolase n=1 Tax=Clostridium carboxidi...   248   1e-64
UniRef50_C1QEL1 HAD-superfamily hydrolase, subfamily IIB n=3 Tax...   248   2e-64
UniRef50_A6LS28 Cof-like hydrolase n=4 Tax=Bacteria RepID=A6LS28...   248   2e-64
UniRef50_A0M3X3 Haloacid dehalogenase-like hydrolase n=2 Tax=Fla...   247   2e-64
UniRef50_C3WB32 Hydrolase n=3 Tax=Fusobacterium RepID=C3WB32_FUSMR    247   2e-64
UniRef50_B1MWW3 Predicted hydrolase of the HAD superfamily n=3 T...   247   3e-64
UniRef50_C5EF13 Putative uncharacterized protein n=2 Tax=Clostri...   247   3e-64
UniRef50_UPI00018506A2 hypothetical protein Bcoam_01805 n=1 Tax=...   247   3e-64
UniRef50_A0R0M1 Cof protein n=3 Tax=Bacteria RepID=A0R0M1_MYCS2       247   3e-64
UniRef50_C9LXL4 HAD hydrolase, IIB family n=1 Tax=Selenomonas sp...   247   3e-64
UniRef50_C9KL53 HAD hydrolase, IIB family n=1 Tax=Mitsuokella mu...   247   4e-64
UniRef50_Q03GV9 Predicted hydrolase of the HAD superfamily n=2 T...   247   4e-64
UniRef50_C3RM99 Hydrolase n=3 Tax=Bacteria RepID=C3RM99_9MOLU         247   4e-64
UniRef50_Q5HRI8 Hydrolase, haloacid dehalogenase-like family n=6...   247   4e-64
UniRef50_Q7NXV0 Putative uncharacterized protein n=1 Tax=Chromob...   247   4e-64
UniRef50_UPI0001788F0C Cof-like hydrolase n=1 Tax=Geobacillus sp...   246   5e-64
UniRef50_B0TIL9 Cof-like hydrolase n=1 Tax=Heliobacterium modest...   246   5e-64
UniRef50_C2HD37 HAD superfamily hydrolase n=12 Tax=Enterococcus ...   246   5e-64
UniRef50_C7H2Z8 Cof family protein n=2 Tax=Faecalibacterium prau...   246   6e-64
UniRef50_B0MA46 Putative uncharacterized protein n=1 Tax=Anaeros...   246   6e-64
UniRef50_Q04G35 Predicted hydrolase of the HAD superfamily n=2 T...   246   6e-64
UniRef50_D1PP54 HAD hydrolase, IIB family n=1 Tax=Subdoligranulu...   245   9e-64
UniRef50_Q5FQA0 Putative hydrolase of the HAD superfamily n=1 Ta...   245   1e-63
UniRef50_A7VVP1 Putative uncharacterized protein n=1 Tax=Clostri...   245   1e-63
UniRef50_UPI0001C34D0C Cof-like hydrolase n=2 Tax=Clostridium Re...   245   1e-63
UniRef50_A6TMX9 Cof-like hydrolase n=1 Tax=Alkaliphilus metallir...   245   1e-63
UniRef50_A8HYJ4 Haloacid dehalogenase-like hydrolase n=1 Tax=Chl...   245   1e-63
UniRef50_C4RHE6 HAD-superfamily hydrolase, subfamily IIB n=2 Tax...   245   1e-63
UniRef50_Q04CZ3 Predicted hydrolase of the HAD superfamily n=2 T...   245   1e-63
UniRef50_Q5WEW5 HAD superfamily hydrolase n=1 Tax=Bacillus claus...   245   2e-63
UniRef50_C4V674 HAD superfamily hydrolase n=2 Tax=Selenomonas Re...   244   2e-63
UniRef50_C4IB07 Cof protein n=1 Tax=Clostridium butyricum E4 str...   244   2e-63
UniRef50_Q183K1 Putative hydrolase n=5 Tax=Clostridium difficile...   244   2e-63
UniRef50_Q1QY75 Cof protein n=1 Tax=Chromohalobacter salexigens ...   244   2e-63
UniRef50_A7GPW1 Cof-like hydrolase n=2 Tax=Bacillus cereus group...   244   2e-63
UniRef50_A0PYI8 Cof family protein , putative n=4 Tax=Bacteria R...   244   2e-63
UniRef50_C4L3T6 Cof-like hydrolase n=2 Tax=Exiguobacterium RepID...   244   2e-63
UniRef50_C7HRV4 Hydrolase (HAD superfamily) n=1 Tax=Anaerococcus...   244   2e-63
UniRef50_A3MZH9 Predicted hydrolases of the HAD superfamily n=9 ...   244   2e-63
UniRef50_C6PAK2 Cof-like hydrolase n=1 Tax=Thermoanaerobacterium...   244   2e-63
UniRef50_C9LLD7 HAD hydrolase, IIB family n=1 Tax=Dialister invi...   244   2e-63
UniRef50_C4Z320 Putative uncharacterized protein n=2 Tax=Bacteri...   244   2e-63
UniRef50_UPI0001C17161 HAD-superfamily hydrolase subfamily IIB n...   244   3e-63
UniRef50_C9PP31 Phosphatase YbhA n=1 Tax=Pasteurella dagmatis AT...   244   3e-63
UniRef50_C6DH90 Cof-like hydrolase n=1 Tax=Pectobacterium caroto...   243   3e-63
UniRef50_Q1IMT6 Cof protein n=1 Tax=Candidatus Koribacter versat...   243   3e-63
UniRef50_Q1G860 Hydrolase (HAD superfamily) n=2 Tax=Lactobacillu...   243   3e-63
UniRef50_A9BES4 Cof-like hydrolase n=1 Tax=Petrotoga mobilis SJ9...   243   3e-63

Sequences not found previously or not previously below threshold:

UniRef50_Q67P94 Haloacid dehalogenase-like hydrolase n=1 Tax=Sym...   247   4e-64

>UniRef50_A0KR21 Hydrolase, Cof family n=3 Tax=Aeromonadaceae RepID=A0KR21_AERHH
          Length = 270

 Score =  318 bits (817), Expect = 1e-85,   Method: Composition-based stats.
 Identities = 123/264 (46%), Positives = 166/264 (62%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+VV SDLDGTLL+  H +SP  ++TL  L  +GI FV ATGRHHVDV  IRD L +  
Sbjct: 1   MYKVVVSDLDGTLLNGQHQISPRTRDTLHRLVDQGIKFVVATGRHHVDVRSIRDTLGLDI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGA VHD    LIF   L   +A++L   +  +P I  N+Y  DEW +    P  
Sbjct: 61  YLITSNGAVVHDKQDQLIFNQALPDGVAAELIA-LERDPSIHINLYYGDEWLVEEEMPWL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++F  E+ F Y L +      + V+KVF+  + HE+LL +E  +N R+GDR+NV+FS   
Sbjct: 120 LQFHHESGFSYRLTDLASHPLDKVNKVFYIGE-HEKLLQIEAELNQRYGDRLNVTFSLPD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM  GV KG+A+ AV ++ G  +   +AFGDGMND EMLSM G+G +MG+AH RLK 
Sbjct: 179 CLEVMHAGVHKGNAVRAVLEQHGLEMSQAVAFGDGMNDFEMLSMVGRGVVMGNAHDRLKL 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                E   ++ +D V  YL +L+
Sbjct: 239 ALANHEQTLSSDEDGVAVYLEQLF 262


>UniRef50_P27848 Uncharacterized protein yigL n=168 Tax=Bacteria RepID=YIGL_ECOLI
          Length = 266

 Score =  316 bits (812), Expect = 4e-85,   Method: Composition-based stats.
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS
Sbjct: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE
Sbjct: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT
Sbjct: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD
Sbjct: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240

Query: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266
           LHPELEVIGTNADDAVPHYLRKLYLS
Sbjct: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266


>UniRef50_A1HSX6 Cof-like hydrolase n=1 Tax=Thermosinus carboxydivorans Nor1
           RepID=A1HSX6_9FIRM
          Length = 272

 Score =  300 bits (770), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 75/264 (28%), Positives = 117/264 (44%), Gaps = 4/264 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A DLD TLL     +S  A+E +    ARG+    ATGR +         L +   
Sbjct: 3   IKLIAVDLDDTLLDNSLAVSARAREAIAQAVARGVTVTVATGRMYRSALPYARQLGLDVP 62

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NGA +     G ++    L  D+A D+  +          VY DD  ++       
Sbjct: 63  LITYNGALIKAALSGEVLLHRPLAEDVARDVLALSRQQ-GWYIQVYLDDVLYVTELNDRA 121

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           + +   A  +       L    G             +L +++ + AR+GDR+    S   
Sbjct: 122 LYYETIAGVKAVPIGDRLYSLPGAPTKLLVMAEPADILRIQEEVQARFGDRLYAVVSKPN 181

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE++   V+KG AL  +A+KLG S  + +A GD  ND +ML  AG G  MG+A QR+K 
Sbjct: 182 YLEMVHPAVNKGAALAFLAEKLGISRDEVMAIGDSYNDLDMLEYAGFGVAMGNASQRVKA 241

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
           +     V   N +D V   + K+ 
Sbjct: 242 VAQA--VTRGNDEDGVAEAIEKIL 263


>UniRef50_C6CW76 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CW76_PAESJ
          Length = 268

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 74/266 (27%), Positives = 130/266 (48%), Gaps = 4/266 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+D TLL+ D  ++   K+ ++   A G+    ATGR +    +I D +++  
Sbjct: 1   MYKLIAIDVDDTLLNDDLIVTEGTKKAMEDAIALGVTVTLATGRMYASAKKIADQIQLNV 60

Query: 61  YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +IT  G+ V  L DG +++   + +D A +L+ +      +   +Y DD  ++     +
Sbjct: 61  PIITYQGSLVKTLLDGEVLYERCVPQDAAKELYAITEQR-GLHLQLYADDILYVKEANEK 119

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            +++       Y + E      +  +      D    L  L + +    GDRV+++ S  
Sbjct: 120 AIKYSTLTNIPYVVAEDFEALLDKPNNKMLIIDDPAYLDQLAEELKPIIGDRVHITKSKP 179

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             LE M    +KGHAL  +A+ LG  ++  IA GD  ND EM+  AG G  MG+A  +LK
Sbjct: 180 HYLEFMHKEGTKGHALRFMAEHLGCGVEQTIAIGDAWNDHEMIEAAGLGVAMGNATPKLK 239

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
           ++     +  TN ++ V H + K  L
Sbjct: 240 EIAD--YITLTNNEEGVRHVIEKFVL 263


>UniRef50_Q7MQB3 Predicted hydrolase n=59 Tax=Gammaproteobacteria RepID=Q7MQB3_VIBVY
          Length = 276

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 129/265 (48%), Positives = 188/265 (70%), Gaps = 2/265 (0%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VASDLDGTLL+P+H LS ++K+TLK L  +G  F+FATGRHHVDV  IR  + I +YM
Sbjct: 12  KIVASDLDGTLLAPNHQLSEFSKQTLKALHEQGYTFIFATGRHHVDVAGIRAQVGIPAYM 71

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ITSNGARVHD    L+++ N+  ++   +  +V  +P+I  ++Y++++W +NR      +
Sbjct: 72  ITSNGARVHDQHDQLMYSKNVPAELVQPVIDIVKQDPEIFVHLYQNEDWRLNREDEVMRK 131

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCD--SHEQLLPLEQAINARWGDRVNVSFSTLT 180
           F +E  F Y +Y+      +G++K+FFT     HE L+  E  +   +GD++N++FST  
Sbjct: 132 FHEETGFTYKVYDIDNAPTDGIAKIFFTHPEQDHEHLVGFENQLREAFGDQLNIAFSTPW 191

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVMA  VSKG AL+AVA+ LG +L++C+AFGDGMND EMLSMAGKG +M ++H+++K 
Sbjct: 192 CLEVMAAEVSKGDALKAVAESLGLTLENCVAFGDGMNDVEMLSMAGKGLVMETSHEKVKK 251

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P+ E+IG+NADDAV HYL+K  L
Sbjct: 252 ALPDNEIIGSNADDAVAHYLQKHLL 276


>UniRef50_C4LAX9 Cof-like hydrolase n=28 Tax=Bacteria RepID=C4LAX9_TOLAT
          Length = 270

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 64/270 (23%), Positives = 109/270 (40%), Gaps = 6/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY+++A D+DGTLL  D T+S   K  ++    +G+  V A+GR    + +    L +  
Sbjct: 3   MYKLIALDMDGTLLRGDGTISERTKSAIQQARQKGVKVVLASGRPIEGLERYLTELGLTT 62

Query: 59  -KSYMITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y ++ NGA + ++     I +  +      D++ V             +      + 
Sbjct: 63  DDDYALSYNGALIKNVGTRENICSQLISGKDLHDVYAVSQQIGVNTHAFSTELGLISPKL 122

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
               +           L +   L  +         D  E L P  + +   + DR  V  
Sbjct: 123 SHYTVHERDINGIPLTLIDFNELAEDHQIIKVMLVDEPEILSPGVEQLPVDYYDRFTVVR 182

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE++    +KG+ +  +A  LG   ++ I  GD  NDA ML  AG    MG+A  
Sbjct: 183 SAPFFLEILNKNSNKGNGVSMLADYLGIKAEEVICVGDAGNDAHMLEYAGLSVAMGNAFD 242

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +K +     V  +N +D V H + K  L+
Sbjct: 243 DIKAIAD--YVTHSNEEDGVAHVIEKFILA 270


>UniRef50_P54947 Uncharacterized protein yxeH n=10 Tax=Firmicutes RepID=YXEH_BACSU
          Length = 270

 Score =  291 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 61/272 (22%), Positives = 114/272 (41%), Gaps = 9/272 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           MY+++A D+DGTLL+  H ++   ++ L    A G+  V  TGR    V +  D L +  
Sbjct: 1   MYKLIAIDMDGTLLNDHHEVTEEVRDALHAAKAEGVKIVLCTGRPIGGVQRYLDELNLIE 60

Query: 60  --SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I  NGA V +     ++   +L  D  + L+ +  +      + +     +    
Sbjct: 61  EGDYVIAYNGALVQNTHTNEVVSELSLGYDDLTSLYDLSLELK-TPMHFFDSSNLYTPNR 119

Query: 117 RPEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
              E   ++  V Q  L+  +   +  + +       D  E L  +  +I     ++  +
Sbjct: 120 DISEFTVYESYVTQVPLHFRKIDEVPKDILIPKVMFIDKPENLSRVITSIPKDVREKYTM 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S     E++    SKG+A+  +A+ LG    + +  GD  ND  M+  AG G  M +A
Sbjct: 180 VRSAPFFYEILHSEASKGNAVRQLAQLLGIEQAEVMCIGDNGNDLTMIEWAGCGVAMANA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              + +         +N +  V H + +L L+
Sbjct: 240 IPEVLEAAN--FQTRSNNEHGVAHAIHELVLA 269


>UniRef50_C9KQV0 HAD-superfamily hydrolase, subfamily IIB n=2 Tax=Veillonellaceae
           RepID=C9KQV0_9FIRM
          Length = 309

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 62/265 (23%), Positives = 106/265 (40%), Gaps = 5/265 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++  +DLDGTLL     +     E ++     G+    ATGR +     + + L +   +
Sbjct: 42  KLFVTDLDGTLLPSGKDVPRENIEAVQQAVRAGVIVTIATGRMYRAALPVAEALGVDVPI 101

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           IT NGA +    G +     L  ++   +     +        Y  DE ++  H      
Sbjct: 102 ITYNGALIKSTQGKVYHTSYLKPEVIRQVVDFCQEQ-GWYLQSYSRDELWVPVHDEHAQH 160

Query: 123 FFKEAVFQYALYEPGLL--EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           + +E      +     L  + + V K+    +  E+       +N R+G  +    S   
Sbjct: 161 YEQEQKVTGHVVGWDGLCEQTQEVCKLLTVSEDGEETNRRLAILNERFGKEIVAMQSNAR 220

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
             E++  GVSK   +  +A KLG +++D +A GD  ND  ML  AG    MG+A   +K 
Sbjct: 221 YGEIVNPGVSKAEGIRRLADKLGIAIEDTMAIGDSYNDLPMLKAAGHSVAMGNAVPEVKA 280

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
           +       G   D      +R+L L
Sbjct: 281 VCD--YETGRCEDFGFAQAIRELVL 303


>UniRef50_Q0B097 Putative uncharacterized protein n=1 Tax=Syntrophomonas wolfei
           subsp. wolfei str. Goettingen RepID=Q0B097_SYNWW
          Length = 268

 Score =  290 bits (744), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 68/267 (25%), Positives = 123/267 (46%), Gaps = 6/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLD TLL     +     E +  +  +G+    ATGR           L++   
Sbjct: 3   IELVAIDLDDTLLDSTWKIPESCLEAISQVQRKGVRVTLATGRMFRSALPYAQQLKVDIP 62

Query: 62  MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT  GA V +     +++   L R +A+++     +   I    Y +D + + R  PE 
Sbjct: 63  LITYQGALVKNSFSQEVLYYEPLPRKLAAEIMIFFKER-GIFYQSYFNDCFCIERWSPEA 121

Query: 121 MRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
             + + +  +   Y+  +     +   K+  +      +L +E+ +N R+G+ + ++ S 
Sbjct: 122 QYYAELSGMEPLFYDDLIAVSREQDTPKILASIFDERLMLAIEEELNRRYGEELYITRSK 181

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LEVM   V KG AL+ +A+  G   +  +AFGD  ND  M+  AG G  MG+A + +
Sbjct: 182 PVFLEVMKRSVDKGLALKMLARYFGIPREKVLAFGDSYNDLAMIKWAGIGVAMGNAPEVV 241

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K+      +  +N ++ V H L +L L
Sbjct: 242 KEAAD--YLAPSNEEEGVAHVLHELIL 266


>UniRef50_B8DEX6 Phosphatase YidA n=17 Tax=Listeria RepID=B8DEX6_LISMH
          Length = 270

 Score =  290 bits (743), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 69/271 (25%), Positives = 121/271 (44%), Gaps = 9/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           MY+++A D+DGTLL+ DH ++   KE ++    +G+  V  TGR  V V      LE++ 
Sbjct: 1   MYKLIAIDIDGTLLTDDHKVTDEVKEAIRQAKLKGVKVVLCTGRPLVGVENYLTELELRE 60

Query: 60  --SYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I+ NGA V D     +I    L  D   +++ V  D  ++  + + D   +    
Sbjct: 61  EGDYVISFNGAFVQDTFTKEVISHLTLGIDDLKEIYQVSLD-SNLHMHFFDDKALYTPNR 119

Query: 117 R--PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                 +        Q    E   +  + +       +   +L      I   + ++ ++
Sbjct: 120 EIGKYTIVEAYLTGSQLIYKEIENVPEDFIMSKAMFIEEAPELEVGIAKIPESFREKYHL 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             ST   LE++    SKG+A++ +++K+G    + +  GD  ND  ML  AG G  MG+A
Sbjct: 180 VRSTPFYLEILNRDASKGNAVKELSEKIGIKQSEVMCIGDQENDVTMLEFAGLGIAMGNA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +R+K L        +N D  V   ++K  L
Sbjct: 240 PERIKQLAD--YTTASNNDSGVAKAIQKFVL 268


>UniRef50_D0BNB6 Phosphatase YidA n=2 Tax=Granulicatella RepID=D0BNB6_9LACT
          Length = 274

 Score =  289 bits (740), Expect = 9e-77,   Method: Composition-based stats.
 Identities = 61/272 (22%), Positives = 112/272 (41%), Gaps = 9/272 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A D+DGTL++  H ++P     L     +G+  V  TGR    V    + L +  
Sbjct: 1   MIKLIAIDIDGTLINSKHEITPRVHAALTKAKEQGVYVVLCTGRPLPGVQGYLNELNLIN 60

Query: 59  -KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
            + ++IT NG+ V     G  +    +  D    L    +    +  +   +   ++   
Sbjct: 61  DRDFVITYNGSLVQKTGTGESLVRFGMTMDDL-KLMDDYHQQYGVHYHAIDEKNIYVTTP 119

Query: 117 RPEEMRFFKEAVFQYALYE--PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
              +  + +  +    + +      +P          D  E L  L   ++  + +  N+
Sbjct: 120 DIGKYSYMERDLVGMPIVQQPLDQFDPNATFSKMMFVDEPEILENLIPNLSDSFKENHNI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LEV+    SKGHA+  +A+ LG    + +  GD  ND +M+  AG G  MG+A
Sbjct: 180 VRSMPVYLEVLHPQASKGHAVAKLAELLGLDASEVMCIGDQGNDRDMIEYAGMGVAMGNA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              +K+L     +  TN +D V   +    L+
Sbjct: 240 IDEIKELAN--FITTTNDEDGVAVAVETHVLN 269


>UniRef50_Q2RLU7 HAD-superfamily hydrolase subfamily IIB n=1 Tax=Moorella
           thermoacetica ATCC 39073 RepID=Q2RLU7_MOOTA
          Length = 272

 Score =  288 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 77/269 (28%), Positives = 122/269 (45%), Gaps = 9/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLDGTLL+ D  + P A+E ++ +  +GI    ATGR           L ++  
Sbjct: 4   IRLVALDLDGTLLTDDIVIEPRAREAIRKVKEKGITVTLATGRMFSSARPYAVELGLELP 63

Query: 62  MITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I  +GA+V H   G ++F   L   +A  L   + +      NVY DD  ++   + E 
Sbjct: 64  LIVYHGAQVRHSTTGEILFERTLPVPLALRLIKNIKEF-GYPYNVYLDDRLYVESIQAEN 122

Query: 121 MRFFKEAVFQYALYEP----GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             +   A       E        +P+G  K+    D    L PLE AI    G  + ++ 
Sbjct: 123 EEYAWRAGVDLHRVEDMLTFLEQQPKGPLKIVALHDGPA-LDPLEAAIRREAGAGIYITR 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S  T LE++   V+K   L+A+A+  G S ++ +  GD  ND +M   AG    M +A +
Sbjct: 182 SMPTYLELLNPEVNKARGLQALAELEGISPEEIMVCGDSYNDVQMFRYAGLAVAMANAPE 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +++       V G+N D  V   L K  L
Sbjct: 242 KVRAEAD--YVTGSNNDGGVAQALEKFVL 268


>UniRef50_B8I4P5 Cof-like hydrolase n=2 Tax=Clostridium RepID=B8I4P5_CLOCE
          Length = 273

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 69/277 (24%), Positives = 120/277 (43%), Gaps = 17/277 (6%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++VA DLDGTLL  +  +S   K  + +   +G+  V  +GR +         L I  
Sbjct: 1   MYRLVAIDLDGTLLDKNKEISERNKIAIHMAKEKGVKIVICSGRVYSGARIYAKQLGIMD 60

Query: 61  YMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +I  NGA +  + DG +I+++ +  D    +  + ++N  I  +VY  +     R    
Sbjct: 61  PIIACNGAIIRENADGKVIYSNYMHTDDCLKILDIFHENS-IYFHVYAGETMLTERLDYN 119

Query: 120 EMRFFKEAV-------FQYALYEPGLLEPE----GVSKVFFTCDSHEQLLPLEQAINARW 168
            +++++           +  +        +     V K+    D  E L  + + ++   
Sbjct: 120 SLKYYERNKALHAKDRVEIDIVTDMEKRLKELDGKVLKLVAVSDDSELLATVRKKLS--I 177

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
            + V+V+ S     EV+  GV+KG ALE ++  L    ++ IA GD  ND  M   AG G
Sbjct: 178 VETVDVTSSNYNNFEVVNKGVNKGKALERLSNMLKIPYREIIAIGDNENDIPMFDFAGLG 237

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             MG+     K+      +  TN +D V   + K  L
Sbjct: 238 VAMGNGEDCAKEAAD--YITATNTEDGVAKAIEKFIL 272


>UniRef50_C6JR95 Hydrolase n=2 Tax=Fusobacterium RepID=C6JR95_FUSVA
          Length = 266

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 101/265 (38%), Positives = 173/265 (65%), Gaps = 2/265 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ +  DLDGTLL+  HT+S Y ++ +K +T  G+ F  ATGRHH+D  + ++ L + SY
Sbjct: 3   YKAIVCDLDGTLLNSQHTISKYTRDVIKDVTNLGVKFFIATGRHHMDALKFKEMLGLDSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+SNGAR+H+ +  +IF  ++ +++++++F  +N N +I  N+Y+DD WF  +   E  
Sbjct: 63  LISSNGARIHNENNEIIFKGDIPKELSNEIFD-LNINEEIYKNIYKDDFWFSEKPLDEAH 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            + KE+ F Y++ +   L+   V K F+  +  + +  LE  IN ++G+R+N++ S   C
Sbjct: 122 EYHKESGFTYSVRKFSELKNSEVIKFFYINEDEKLIRNLENEINEKFGNRINLTLSLPIC 181

Query: 182 LEVMAGGVSKGHALE-AVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           LE+M  G+SKG+A++  +  K   + ++ I+FGDG+ND EML + G+G +MG+ + RLK+
Sbjct: 182 LEIMNKGISKGNAIKDILLPKFKITPEEVISFGDGLNDYEMLDIVGEGLLMGNCNPRLKE 241

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
           L P  +VIG N +D V  YL+K++L
Sbjct: 242 LLPNNKVIGRNDEDGVAEYLKKVFL 266


>UniRef50_Q38V42 Hydrolase, haloacid dehalogenase family n=2 Tax=Lactobacillales
           RepID=Q38V42_LACSS
          Length = 273

 Score =  286 bits (734), Expect = 5e-76,   Method: Composition-based stats.
 Identities = 72/274 (26%), Positives = 112/274 (40%), Gaps = 13/274 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            ++VA D+DGTLL+ ++ LSP   E +K   A+GI  V  TGR    V      L +   
Sbjct: 3   IKLVAVDMDGTLLNENNVLSPKTIEVVKAAKAQGIKVVLCTGRPLTGVTPFLHELGLTDS 62

Query: 61  --YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+IT NGA V +   G ++  H L      +L   ++    +  +   D   +     
Sbjct: 63  SDYVITFNGALVQNTATGEILVRHTLTHAQYLEL-ETLSRTIGVHLHAEDDQFIYTANRD 121

Query: 118 PEEMRFFKEAVFQYAL---YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                  + A+    +   +   +   +  SKV    D  E L   +  I A + DR   
Sbjct: 122 ISPYTIGESALVNMPIKFRHVDEIAPDKAFSKVMLI-DDPEVLAEGKAKIPADFFDRYQF 180

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LEV+     KG+ L  +A  L     + +A GD  ND  ML+ AG    M +A
Sbjct: 181 VQSEPYFLEVLNTKAGKGNGLRDLANALNIDQSEVMAVGDQGNDLSMLAYAGLPVAMDNA 240

Query: 235 HQRLKDLHPELEVIGTNA--DDAVPHYLRKLYLS 266
              LK +     +  +N    D V + + K  L+
Sbjct: 241 IPELKKIAK--VITKSNHLGQDGVAYAIEKYALN 272


>UniRef50_P0A8Y6 Phosphatase yidA n=235 Tax=cellular organisms RepID=YIDA_ECOL6
          Length = 270

 Score =  286 bits (733), Expect = 6e-76,   Method: Composition-based stats.
 Identities = 71/271 (26%), Positives = 111/271 (40%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            +++A D+DGTLL PDHT+SP  K  +    ARG+N V  TGR +  V      L ++  
Sbjct: 3   IKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTGRPYAGVHNYLKELHMEQP 62

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y IT NGA V    DG+ +    L  D    L  +  +      +       +     
Sbjct: 63  GDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE-VGSHFHALDRTTLYTANRD 121

Query: 118 PEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                  +  V    L   E   ++P          D    L      I     ++  V 
Sbjct: 122 ISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEPAILDQAIARIPQEVKEKYTVL 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE++   V+KG  ++++A  LG   ++ +A GD  ND  M+  AG G  M +A 
Sbjct: 182 KSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAIGDQENDIAMIEYAGVGVAMDNAI 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K++     V  +N +D V   + K  L+
Sbjct: 242 PSVKEVAN--FVTKSNLEDGVAFAIEKYVLN 270


>UniRef50_B0K874 Cof-like hydrolase n=10 Tax=Thermoanaerobacteraceae
           RepID=B0K874_THEP3
          Length = 274

 Score =  285 bits (732), Expect = 8e-76,   Method: Composition-based stats.
 Identities = 70/275 (25%), Positives = 121/275 (44%), Gaps = 16/275 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+D TLL  D T+S    E L     +G+  V +TGR         D +  ++Y
Sbjct: 3   YKLIAIDMDDTLLRHDKTISKENIEALHKAREKGVYVVISTGRVFASAYAYADMIGFRTY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I SNGA + D D N I+   L+ D   ++  V     +    +  D   F      +  
Sbjct: 63  IIASNGALIRDPDNNTIYESLLNYDSMEEIIKVCQKY-NTYFQLISDKTVFSPEITNKFQ 121

Query: 122 RFFK-------EAVFQYALYEPGLLEPEG----VSKVFFTCDSHEQLLPLEQAINARWGD 170
           R+ +       E        +  L E +     + K+    D  E L  + + ++     
Sbjct: 122 RYAEWNELFKTELKVDVQEVKEPLKELDKLKSSILKIIVFNDDVEVLKSIREELSKNTS- 180

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + ++ S +  +E++  GVSKG AL+ +   LG   ++ IA GD  ND EM+  AG G  
Sbjct: 181 -IQITSSYMDNIEIVNKGVSKGRALKILGGYLGIEREEMIAIGDSENDIEMIKFAGLGVA 239

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           + +A   +K +     +  +N +D V + + K  L
Sbjct: 240 VENAIDEVKKVAD--FITKSNMEDGVKYVIDKFIL 272


>UniRef50_A8U9P8 Hydrolase, haloacid dehalogenase-like family protein n=1
           Tax=Carnobacterium sp. AT7 RepID=A8U9P8_9LACT
          Length = 269

 Score =  284 bits (728), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 71/273 (26%), Positives = 120/273 (43%), Gaps = 11/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           M ++VA DLDGTLL+ +H +S   KE +K    +G+  V  TGR  + +    + L ++ 
Sbjct: 1   MIKLVAIDLDGTLLNREHIISDENKEVIKKAKEQGVKVVLCTGRPLLGMISYLEELNLRE 60

Query: 60  --SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NG  V   D G ++    L +    ++F +  +  ++  N    ++ +    
Sbjct: 61  VGDYGITYNGGLVQRTDTGEVLSKKTLTKVEIEEIFALSKEI-NVPCNFIDLEKIY-EPP 118

Query: 117 RPEEMRFFKEAVFQYALYEPGLLE---PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            PE        V +   Y P  +E    +        C     L    + I   + ++  
Sbjct: 119 YPEGRDSLYPTVMRALPYVPIEMEHVSEDIAINKTVFCYEQTSLDEAIKKIPVHFHEKYT 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +  S    LE+M  GV KG  +  +A  LG+   + ++ GD  NDA M+  AG G  MG+
Sbjct: 179 IMKSRPVLLELMPKGVDKGSGIAVLADLLGFEASEVMSLGDEANDAAMIEYAGMGVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A   +K +     +  TN +  V H ++K  L+
Sbjct: 239 ATDEIKAMA--QYITKTNEEHGVAHAIQKFVLN 269


>UniRef50_Q5XD45 Putative hydrolase M6_Spy0533 n=25 Tax=Streptococcaceae
           RepID=Y533_STRP6
          Length = 269

 Score =  284 bits (727), Expect = 3e-75,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 121/271 (44%), Gaps = 10/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            ++VA D+DGTLL+ D  ++    + ++   A+G++ V ATGR    V  + + LE+   
Sbjct: 3   IKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATGRPIAGVISLLEQLELNHK 62

Query: 60  -SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
            +++IT NG  V D + G  I    +  D   +    ++    +  +    +  +     
Sbjct: 63  GNHVITFNGGLVQDAETGEEIVKELMTYDDYLET-EFLSRKLGVHMHAITKEGIYTANRN 121

Query: 118 PEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             +    +  +    ++   P  +  + + K+    D  + L    + I   + D+  + 
Sbjct: 122 IGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMI-DEPDLLDAAIKQIPQHFFDKYTIV 180

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            ST   LE M   VSKG+A++ +AKKLG  +   +A GD  ND  ML +     +M +  
Sbjct: 181 KSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIGDAENDRAMLEVVANPVVMENGV 240

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             LK +     +  +N D  V H +RK  L+
Sbjct: 241 PELKKIAK--YITKSNNDSGVAHAIRKWVLN 269


>UniRef50_C3WN06 Hydrolase n=12 Tax=Fusobacterium RepID=C3WN06_9FUSO
          Length = 267

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 96/263 (36%), Positives = 156/263 (59%), Gaps = 2/263 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+  H +S +    +K +   G+ F+ ATGR ++D    RD+LE+KSY
Sbjct: 3   YKLIVCDMDGTLLTSSHKISDHTANIIKKIEDSGVKFMIATGRPYLDARHYRDSLELKSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +ITSNGAR HD D N I   N+ +++   L        DI  N+Y DD+W +       +
Sbjct: 63  LITSNGARAHDEDNNPIVVENIPKELVKRLLNY-KVGKDIHRNIYLDDDWIIEYEIDGLV 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            F KE+ + + + +    + + V+K+FF  ++ E +  LE+ +   + D ++++ S+  C
Sbjct: 122 EFHKESGYGFNIDDLSKYQNQEVAKIFFLGENKE-IEELEKKMKKDFKDELSITVSSPFC 180

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE M  GV+K   L+ V K L    ++ IAFGD MND EMLS+ GK  IMG+A++RL + 
Sbjct: 181 LEFMKKGVNKAETLKKVLKILDIKPEEVIAFGDSMNDYEMLSLVGKPFIMGNANKRLIEA 240

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
            P +EVIG N +D +   L++++
Sbjct: 241 LPNVEVIGNNNEDGIGEKLQEIF 263


>UniRef50_C3WDD5 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WDD5_FUSMR
          Length = 265

 Score =  282 bits (724), Expect = 7e-75,   Method: Composition-based stats.
 Identities = 105/264 (39%), Positives = 159/264 (60%), Gaps = 1/264 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ +  DLDGTLL+  H LS   KE +K +   G     ATGRHH+D   I+  L + SY
Sbjct: 3   YEAIVCDLDGTLLNEKHQLSDETKEVIKKVKDTGKKIFIATGRHHLDALAIKKQLGLDSY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+SNGAR+HD   N ++  N+D + A+ +   V  N +I  ++Y D +W++  H+ E +
Sbjct: 63  LISSNGARIHDEHNNEVYERNIDEETANFILN-VKCNKEIERHIYTDTKWYVEEHKEEYI 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            F KE+ F Y + +   +  E   K+FF   + E+L  LE+      GD+V+++ S   C
Sbjct: 122 EFHKESGFLYEVKDFSKIVGEKFIKIFFISKNQEELFKLEKYFEEVIGDKVSITLSGPEC 181

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+M   V+KG A++ + +KL   L++ +AFGDG+ND EMLS  GKG +MG+  QRL++ 
Sbjct: 182 LELMTKNVTKGEAVKNIMEKLNIPLENTMAFGDGLNDYEMLSEVGKGLLMGNCAQRLREK 241

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
            P  E+IG N D+ V  YLRK +L
Sbjct: 242 LPNNEMIGKNIDNGVAKYLRKTFL 265


>UniRef50_C4FT61 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FT61_9FIRM
          Length = 269

 Score =  282 bits (723), Expect = 8e-75,   Method: Composition-based stats.
 Identities = 70/271 (25%), Positives = 117/271 (43%), Gaps = 10/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A DLDGTLL+    +S   ++ L    ++G+  V  TGR +  +     +L +  
Sbjct: 1   MIKLIAIDLDGTLLNAQKEVSQANRQALAYAKSKGVKVVLCTGRPYFAMKHFLADLGLVD 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
            + Y++T NG  V    DG ++ ++ L        +  V  N D+  NV   D  +    
Sbjct: 61  PEDYIVTFNGGMVQKAQDGQVLVSNTLGTSDVLAWYQ-VTQNLDLPINVIDADRLYEPTA 119

Query: 117 RP---EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            P     +           + +    +P+     F    + E L      ++  + D+  
Sbjct: 120 YPVGYPSLYLENVTNVPSVVQDYKTFDPDHAFNKFVIVTTQEHLDAQIPKLDPDFKDQYA 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V  S    LEVM  GVSKG  L  + + L  S ++ +  GD  ND  M+ +AG G  MG+
Sbjct: 180 VFKSRSFFLEVMKKGVSKGDTLAKLGELLDISPQEMMTMGDQENDLSMIELAGLGVAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           A +++K       V  TN +D V H + K  
Sbjct: 240 ATEQVKASA--QYVSLTNEEDGVAHAIHKFI 268


>UniRef50_Q0SVE4 HAD hydrolase, IIB family n=17 Tax=Clostridium RepID=Q0SVE4_CLOPS
          Length = 279

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 66/280 (23%), Positives = 116/280 (41%), Gaps = 20/280 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+  H +S   KE +K  T RG+     TGR           L +K+ 
Sbjct: 3   YKLICIDMDGTLLNNKHEISERNKEAIKKATERGVKVAVTTGRLFTSAKYYAGLLGVKTP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I+ NGA + + D   +I+   L+ D    ++ V+      +      +     +  PEE
Sbjct: 63  IISCNGAFIREKDEDKVIYESVLNEDQLDRIYNVIKKYDINMAYFNTPNTVISEKIVPEE 122

Query: 121 MRFFKEAVFQYALYEPGLLEP------------EGVSKVFFTCDSHEQLL---PLEQAIN 165
             +           E  +               + + K     +   +L      ++ + 
Sbjct: 123 HGYKVMNKMMGESKEKVMFSEGIDFREAFKTYGKHILKAICIENDSNKLNDLFKAKEELK 182

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
               + + V  S+ +  EVM  G SKG A++ +A  L  + ++ +  GD  ND  M+  A
Sbjct: 183 K--YEDLEVVSSSPSNFEVMNKGTSKGRAVKVLADILNINREEVMCLGDSENDLSMIEFA 240

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G G  MG+A + LK+      +  TN +D V   + K  L
Sbjct: 241 GLGVAMGNAEEFLKEKAD--YITDTNENDGVAKAIEKFVL 278


>UniRef50_C2KV90 HAD superfamily hydrolase n=1 Tax=Oribacterium sinus F0268
           RepID=C2KV90_9FIRM
          Length = 270

 Score =  282 bits (722), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 73/272 (26%), Positives = 131/272 (48%), Gaps = 10/272 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           M++ +A DLDGTL + +  +S   K  L+    RG++ + A+GR    + ++ + LE++ 
Sbjct: 1   MFKAIALDLDGTLTNSEKKVSERNKRALQEAIKRGVSIILASGRPTYGMSEVWEALELEK 60

Query: 60  --SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+++ NG+   D     ++F   + R   + +   V +  D+    Y+  E    R 
Sbjct: 61  LGGYVLSYNGSLCMDCKSKEVLFEKTIPRKYYAPIAQAVRE-ADLGLLSYQGKEIVTERP 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
               M                      E V K+    + HE+LLPL++ +   +G+ +++
Sbjct: 120 EFPYMDRESTINKMPFRKVEDFPNALSEEVCKLLALGE-HEELLPLKERLEKEYGEELSI 178

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
            FS    LE+   GV KG +L+ + +K G+  ++ +AFGDG ND  ML  AGKG  M ++
Sbjct: 179 FFSEPFFLEICPVGVDKGESLKRLLEKKGWKREELMAFGDGGNDLTMLQYAGKGIAMANS 238

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            + + ++    EV  +N +D V   + K  LS
Sbjct: 239 QKHVLEIAD--EVTLSNDEDGVAVMVEKYILS 268


>UniRef50_C6P8T7 Cof-like hydrolase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6P8T7_CLOTS
          Length = 293

 Score =  280 bits (718), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 70/275 (25%), Positives = 123/275 (44%), Gaps = 14/275 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++VA D+D TLL+ D  +S    E L+     GI  V +TGR +       + L  K Y
Sbjct: 22  YKLVAIDMDDTLLTYDKQISRENLEALQKAHDSGIYVVISTGRIYASAYAYSEFLGFKPY 81

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I SNGA + D   N I+   LD D+ S L  + N+N D+  + Y D   +      +  
Sbjct: 82  IIASNGAMIRDDKDNEIYKSVLDVDLISYLINLANEN-DLYYHFYSDKIVYSPESTSKYQ 140

Query: 122 RFFKEAVF-----------QYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
           ++ +                    +      + + K     +  E++  +   I+   GD
Sbjct: 141 KYGEWNRLYAETLRVKVEDIPKDIDFTDKLKDNIVKFVMFDEDSEKIKRVRDIIDNNKGD 200

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           ++  + S    +E++  G++KG+ L  + + LG    + +A GD  ND EM+  AG G  
Sbjct: 201 KLETTSSFYNNIEILNKGINKGNGLRILGEYLGVDRSEMVAIGDSENDTEMVEFAGLGVA 260

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           M +A ++LK       +  +N ++ V + + K  L
Sbjct: 261 MENAIEKLKKTAD--FITKSNMENGVAYVINKFIL 293


>UniRef50_B0K375 Cof-like hydrolase n=11 Tax=Thermoanaerobacterales
           RepID=B0K375_THEPX
          Length = 273

 Score =  280 bits (718), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 69/270 (25%), Positives = 121/270 (44%), Gaps = 7/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++  +D DG+LL+ +  +S   KE +K + +RG+ F  ATGR    +      L I +
Sbjct: 1   MYKLFVTDADGSLLNSNSEISDKNKEAIKEVISRGVIFTIATGRMFSSILPYALELNINA 60

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +I+ NGA + D     + + + +  + A     ++ +      N+Y DDE ++      
Sbjct: 61  PVISYNGALIKDIYTKKVYYYNPIQTEDAIFAIRLLKEI-GYHINLYIDDELYVEEITDR 119

Query: 120 EMRFFKEAVFQYALY---EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
              +              E  L    GV+   +  +  +  + ++  I      R+ +S 
Sbjct: 120 VEWYLSFNNVTVNAVGNLEEFLKRTGGVTAKIYAINDMKNPISIDAEIYDEISKRLTIST 179

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE+ A GVSKG+AL+ +A       +  +A GD +ND  M+  AG G  MG+A  
Sbjct: 180 SGGGHLEINAKGVSKGNALKTLANMYSIKREQVVAIGDNLNDLSMIEYAGLGVAMGNAPD 239

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +K          +N +D V H + K +L+
Sbjct: 240 IVKIKAD--YTTLSNDEDGVAHAIDKFFLN 267


>UniRef50_C2LH85 HAD superfamily hydrolase n=3 Tax=Enterobacteriaceae
           RepID=C2LH85_PROMI
          Length = 272

 Score =  279 bits (715), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 54/269 (20%), Positives = 116/269 (43%), Gaps = 9/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            +++  DLDGTLL+  H ++P   + ++     G++ V A+GR    +      L + + 
Sbjct: 7   IKLIVIDLDGTLLNEQHEITPEVHQAIQHAKNSGVHIVLASGRSFNGISPYLKALNLDTS 66

Query: 61  --YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             + I++NG+++H   +G +I    L+ +       +  +   +  +V  D++ +     
Sbjct: 67  DNFCISNNGSQIHQAENGEIITEDLLNFEDYLYFEDLSREI-GVHFHVLSDNKIYTTNRH 125

Query: 118 PEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                  +  +    LY      ++ +     F    +   L    Q + A    + ++ 
Sbjct: 126 ISHFTCREAFLTWTPLYYRPLSEMQRDMRFSKFMIVGTPTVLDNAMQYLPANIYQQYSIL 185

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    +E++   V+KG+A++ +A+ L  + +  +  GD  ND  ML  AG G  MG+A 
Sbjct: 186 RSAPYFIEILNTDVNKGNAVQKIAEHLKITPEKIMCIGDQDNDLAMLQYAGLGVAMGNAP 245

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           + +K +     +  +N +  V   + K  
Sbjct: 246 EEIKKVAK--FITLSNKEHGVAVAINKFI 272


>UniRef50_Q3AFE4 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Carboxydothermus
           hydrogenoformans Z-2901 RepID=Q3AFE4_CARHZ
          Length = 266

 Score =  279 bits (715), Expect = 6e-74,   Method: Composition-based stats.
 Identities = 72/267 (26%), Positives = 125/267 (46%), Gaps = 8/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLD T L+ +  +SP  ++ +     +GI    ATGR +    +   +      
Sbjct: 3   YRLLAVDLDDTFLNKELQVSPRVQQAVIEALKKGIIVTLATGRMYRSAKKYAFSFLGDIP 62

Query: 62  MITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NGA + +      ++   +  ++A  ++  V        NVY+DDE  +       
Sbjct: 63  LITYNGALIKYSRSEREVYHQPVPGELALTIYRRVK--GHFHLNVYQDDELLVEEDNQYI 120

Query: 121 MRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
             + K A   + +      LL  +  +K+    D  E L  L +  N  +   ++++ S 
Sbjct: 121 RDYSKIAGVPFRVVSNIEELLGKKAPTKLLAIGDPEE-LDQLWEETNGEFRGVLHITKSK 179

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LE +A GV+KG AL+ +A+ LG SL + +A GD  ND EML  AG G  MG+A   +
Sbjct: 180 PHYLEFLAAGVNKGEALKILAQHLGISLTETVAVGDSYNDLEMLEAAGLGVAMGNALPEV 239

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K       V+  N +D + + + ++ L
Sbjct: 240 KRRADL--VVPANDEDGIAYLINEIIL 264


>UniRef50_C6AQ91 Cof protein n=4 Tax=Bacteria RepID=C6AQ91_AGGAN
          Length = 390

 Score =  279 bits (714), Expect = 8e-74,   Method: Composition-based stats.
 Identities = 67/263 (25%), Positives = 119/263 (45%), Gaps = 6/263 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V SD+DGTLL+  H ++P  +E +K +  RGI F+  + R    +    + L  +  
Sbjct: 132 YKAVFSDIDGTLLNSQHQITPKTEEAIKNILKRGIPFIPVSARPPYAITPYTEQLGSQHG 191

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           MI  +GA + D +   +++  L+      L  ++ D   +  + Y   +WF N    + +
Sbjct: 192 MICYSGALILDKNLTALYSVILEPQDLQKLNELLADFAHLSISYYAGLDWFCNDVNNDWI 251

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           +   E        E        V K+     S E++  +E  +       +++  S    
Sbjct: 252 KQESE--ITGLSAELLQGNLTEVHKILVMG-SAEEIQTVEPVLKQALP-HLSIHRSKDEY 307

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+     +K  A++ + + LG S +  IAFGD  ND +ML  AG    MG+A   +K +
Sbjct: 308 LEITNPAATKAKAIQFMERHLGISAEQVIAFGDNFNDLDMLQYAGLSVAMGNAPDAIKQV 367

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
               EV  TN +D +   L +++
Sbjct: 368 AK--EVTATNNEDGIALVLNRVF 388


>UniRef50_Q04GT8 Predicted hydrolase of the HAD superfamily n=2 Tax=Oenococcus oeni
           RepID=Q04GT8_OENOB
          Length = 271

 Score =  279 bits (714), Expect = 8e-74,   Method: Composition-based stats.
 Identities = 68/271 (25%), Positives = 113/271 (41%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            ++VA D+D TLL+  + L+ +  +TLK   A G   V  +GR           L I   
Sbjct: 3   IKLVAIDVDATLLNSRNELTKHTIDTLKEAIAMGTKIVITSGRPLPGTEPYYAKLGIDKK 62

Query: 60  --SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y I  NGA +    G +I    L      D++ + N    +       D  +     
Sbjct: 63  DDQYAINYNGATIRTTSGRMISEATLTIKDYKDIYSLANKI-GVKIQAETADCIYTPYLS 121

Query: 118 PEEMRFFKEAVFQYAL--YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             +   +++ +    +       L+   V       D  E +  +++ + A   DR NV 
Sbjct: 122 APKYTKYEQKLTNAKIRHVRMQDLKKSDVIAKIMFIDEPEIISRVKKELPAWVYDRFNVV 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S+   +E +   VSKG+A+  +A+KLG  +   +A GD  ND  M+  AG G  MG+  
Sbjct: 182 PSSPVYIEFIDKKVSKGNAVRTLAEKLGIDISQVMAIGDQGNDLSMIEAAGVGVAMGNGI 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             LK +     V  +N +D V + + K  L+
Sbjct: 242 DDLKSIA--QFVTKSNDEDGVAYAVEKFLLN 270


>UniRef50_A4XJ23 Cof-like hydrolase n=2 Tax=Clostridia RepID=A4XJ23_CALS8
          Length = 296

 Score =  278 bits (712), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 66/265 (24%), Positives = 127/265 (47%), Gaps = 4/265 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++VA+DLD +LLS D  ++P   + ++ L    +  + A+GR +  V +I  +LE   
Sbjct: 31  MIKLVATDLDDSLLSKDLKITPKNLKAIEFLKKNNVILILASGRPYPSVKKIAYDLENFY 90

Query: 61  YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            MIT  GA V+D  D   ++   +  + A +L  +  +  +I  ++Y D+ W++     +
Sbjct: 91  PMITYQGALVYDPKDDRKLYGCEIQPNDAKELIRLAKE-ENIHVHIYIDNVWYVEVFNEK 149

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
              +      +    +  L   +         D HE+L  L++++   +  + N+ FS  
Sbjct: 150 VEYYKNLTGLEPVKVDNFLEFVDRPVTKVLFFDEHERLRKLKESLPLEFSKKFNIMFSKP 209

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             LE     VSKG+AL+ +A+       + +A GDG ND  M+  AG G  + +A ++LK
Sbjct: 210 FFLEFTDINVSKGNALKFLAQYYNLKRDEIMAIGDGDNDISMIEYAGIGVAVENATEKLK 269

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
           ++     +  +  +    H + K++
Sbjct: 270 EVA--SFITLSCDNSGFAHAVEKVF 292


>UniRef50_Q5DYX0 Predicted hydrolase n=65 Tax=Bacteria RepID=Q5DYX0_VIBF1
          Length = 273

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 54/271 (19%), Positives = 109/271 (40%), Gaps = 8/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY+++A D+DGTLL+ D  +S   K  +     +G+  V A+GR    +    + L +  
Sbjct: 5   MYKLIALDMDGTLLNSDKQISAENKAAIAAAREKGVVVVLASGRPLNGMKPQLEELGMTT 64

Query: 59  -KSYMITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+++ N + V  +    +I +  +    A  +  +  +   +  + +  ++  +   
Sbjct: 65  ENDYVLSYNASLVQKVKNEEVIRSQIITGADAKAIAKLAQE-LGVNVHAFSQEKGLITPA 123

Query: 117 RPEEMRFF-KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                    K       + +   L  +         D  E L    + +      +  + 
Sbjct: 124 LSHYTEHESKITGMPITVIDFEELADDEQILKAMMIDEPELLSAAIKQLPEALYKQFTIV 183

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE +    +KG  +EA+A+ LG +  + I  GD  ND  M+  AG G  M +A 
Sbjct: 184 QSAPFFLEFLNPNSNKGVGVEALAEHLGITADEVICMGDAGNDWHMIKYAGLGVAMANAT 243

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K++   + V  +N +  V   + +  L+
Sbjct: 244 DDVKEIANHITV--SNNEHGVAKVIEEFVLN 272


>UniRef50_C2H930 Haloacid dehalogenase (HAD) superfamily hydrolase n=12
           Tax=Enterococcus faecium RepID=C2H930_ENTFC
          Length = 269

 Score =  277 bits (711), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 65/271 (23%), Positives = 112/271 (41%), Gaps = 9/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++VA DLDGTLL+    +S   K+ L     +G+  V  TGR    +      L +  
Sbjct: 1   MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGRPLAAMAHYLQELGLVD 60

Query: 61  ---YMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NG  V  +  G ++    ++      L+ +     D+  +V  D+       
Sbjct: 61  EGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQ-LDLPLDVLSDNVVLQLPS 119

Query: 117 RPEEMRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
            P +   +     + Q+   +   +  E V          E+L P  + I   + +   +
Sbjct: 120 APRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQEELDPKIKEIPVEFHEMYEI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             +    LE M  GV+K + +  +AK LG   ++ +A GD  ND  M+  AG G  M +A
Sbjct: 180 IKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIGDEENDLPMIQYAGLGVAMENA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
              +K+      V  +N ++ V   ++K  L
Sbjct: 240 VPFVKEAAD--FVTVSNEENGVAKVIQKFVL 268


>UniRef50_D1AJW8 Cof-like hydrolase n=1 Tax=Sebaldella termitidis ATCC 33386
           RepID=D1AJW8_SEBTE
          Length = 262

 Score =  277 bits (710), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 72/264 (27%), Positives = 131/264 (49%), Gaps = 4/264 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + V SDLDGTLL+ + T+S   KE ++ L   GI F  ATGR  + + +  D+LE+ +
Sbjct: 1   MIKAVFSDLDGTLLNENGTVSEETKEMIEKLKKAGIKFFIATGRSFLAMKRFYDHLELDT 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            ++  NGA +H+ DG  IF   LD  +A +L      N ++  + + +++W++  +    
Sbjct: 61  EIVNYNGAVIHNSDGGKIFELTLDDSVARELIDYGRKN-NLYYHGFSNEKWYLEDYNDTA 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             +  ++  Q  +     +     +K+ F     E    ++  +  ++ +++    S+ T
Sbjct: 120 KAYGAKSQLQENIINFDNMPKLDFNKMMFIN-DAETTKIVDSYVIEKYKNKIYKGLSSPT 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE+M   VSKG+A++ + +K G+   + IAFGD  ND EML     G  M +A+  +K 
Sbjct: 179 FLEIMNPDVSKGNAVKFLLEKYGFQPDEVIAFGDAENDLEMLFSVKYGVAMENANDEVKS 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                 +   N ++ V  +L    
Sbjct: 239 --KVNYIAPKNTENGVALFLEDFL 260


>UniRef50_Q891C8 Hydrolase (HAD superfamily) n=3 Tax=Bacteria RepID=Q891C8_CLOTE
          Length = 320

 Score =  277 bits (709), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 62/270 (22%), Positives = 107/270 (39%), Gaps = 7/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++VA D+DGTLL    T+       +K  + +GI    ATGR    +    + L + S
Sbjct: 52  MYKLVAIDMDGTLLDDSKTIPNENIRAIKEASNKGIKIALATGRPLTGIKNYLNVLGLNS 111

Query: 61  Y---MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
                I  NGA + +  +  +I    L+ D       +      I  NV+  D    ++ 
Sbjct: 112 PDNFSIIYNGALIQNNTNKKIISQCLLNYDDLMYFHNLSRKF-HIHMNVFTKDSCITSKL 170

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                   K +     + +   L+           D  E +  +   ++     +  ++ 
Sbjct: 171 GKYTTLEAKWSNIDVKIVDFNNLDKNIEITKVIFADEPELISKIMDNLDDDVYSKYAMAR 230

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE     ++KG A++  A  L    ++ I  GD  ND EM+  AG G  M +A  
Sbjct: 231 SAPYFLEFFNKEINKGIAVKKYADSLNIHKEEIICIGDAGNDIEMIKFAGLGIAMENAFP 290

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +K++     +  +N +  V H + K  LS
Sbjct: 291 EIKNVAN--YITLSNENAGVAHAIDKFILS 318


>UniRef50_B8FYX3 Cof-like hydrolase n=2 Tax=Desulfitobacterium hafniense
           RepID=B8FYX3_DESHD
          Length = 270

 Score =  276 bits (708), Expect = 5e-73,   Method: Composition-based stats.
 Identities = 61/249 (24%), Positives = 109/249 (43%), Gaps = 8/249 (3%)

Query: 21  SPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNGARVHDL-DGNLIF 79
           S    E ++    +G+   FATGR  V      + L +   +IT NGA + +     +++
Sbjct: 22  SERVVEAIRQARGQGVYVTFATGRMPVSARPYAEQLGLDVPIITYNGAMIQEAISREILY 81

Query: 80  AHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLL 139
              +   +A ++ G +        ++YR D  F+ +       + ++        +   +
Sbjct: 82  RKVIPVALAREVVGFLL-GEGAHLHMYRKDRVFVQKMNEWSRSYGQKTKVTVEEADLITI 140

Query: 140 ---EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALE 196
              E EGV K+       E+L    Q +  R   R++++ S    LE+    V+KG+ L 
Sbjct: 141 LEDEKEGVEKIIVFG-PPEELADWRQKLGQRLPGRLHLTSSKSYFLEMGHPEVNKGNTLL 199

Query: 197 AVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAV 256
             A+ LG   ++ +A GD +ND EM+  AG G  MG+A   +KD      V  +N +D V
Sbjct: 200 TFAQGLGIKPEEVMAIGDSLNDLEMIRCAGLGVAMGNALPEVKDAAD--VVTASNEEDGV 257

Query: 257 PHYLRKLYL 265
              + +  L
Sbjct: 258 AKAIEEYVL 266


>UniRef50_A8GAR8 HMP-PP phosphatase n=39 Tax=Enterobacteriaceae RepID=COF_SERP5
          Length = 274

 Score =  275 bits (706), Expect = 8e-73,   Method: Composition-based stats.
 Identities = 109/265 (41%), Positives = 153/265 (57%), Gaps = 3/265 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++ A D+DGTLL+PDH + P     LK L  R +   FATGRH++D   I   L ++ 
Sbjct: 1   MYRLAAFDMDGTLLTPDHRVGPETLAVLKQLVEREMVVTFATGRHYLDAQPIMAQLGLQG 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+IT NG RV+D  G  + A +L  DIA ++    + + D   +V+RD+ W      PEE
Sbjct: 61  YLITGNGTRVYDDRGQQLQATDLPADIAEEVL-HTHWHTDASMHVFRDEGWMTEFAVPEE 119

Query: 121 M-RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
           M R    + F Y L E   L   G SKV F    HE+LL L+  +   +  RV++ FS  
Sbjct: 120 MLRAHHLSGFHYQLTELRRLPAFGNSKVCFAG-PHEELLKLQVQLRRHFAARVDLCFSAY 178

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
            CLEV+  G +KG AL+ +++ LG  + +C+AFGD MND EML+  G G +MG+A  +LK
Sbjct: 179 ECLEVLPLGCNKGSALDMLSRHLGLKMAECMAFGDAMNDKEMLATVGHGVVMGNALPQLK 238

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
            L P+L+VIG     AV HYL+   
Sbjct: 239 SLLPQLQVIGHCEQQAVAHYLQHWL 263


>UniRef50_UPI0001C365F0 putative haloacid dehalogenase-like hydrolase n=1 Tax=Clostridium
           hathewayi DSM 13479 RepID=UPI0001C365F0
          Length = 299

 Score =  275 bits (706), Expect = 9e-73,   Method: Composition-based stats.
 Identities = 70/271 (25%), Positives = 113/271 (41%), Gaps = 10/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++  DLDGTL + D  ++P  KE L  L ++G   V A+GR    +  +   L +   
Sbjct: 33  YRMIVLDLDGTLTNRDKVITPRTKEALMKLKSQGGTIVLASGRPTYGIMPLARELGLTED 92

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NG R+ +   G  +FA  L       +  +  ++  +    Y  D        
Sbjct: 93  GGYILSFNGGRIIECRSGETVFAKELPVASNKKIIALAKEH-GVNILTYEGDCIITPDSG 151

Query: 118 PEEMRFFKEAVFQYALYEPGLLE--PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
              ++   +             E     V K     D  + L  +E  + A  G   +V 
Sbjct: 152 DIYVKKESDINKLEVRKVENFAEYVDFPVVKFLLL-DDGDYLALVEPKVKAALGRDYSVY 210

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LEV+  G+ K  +LE +  +L  +  + IA GDG ND  M+  AG G  M +A 
Sbjct: 211 RSEPYFLEVLPKGIDKAASLERLLTRLDMTKDEMIACGDGYNDLSMIQYAGLGVAMENAV 270

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K+      V  +N DD V H + K  LS
Sbjct: 271 LPVKNAAD--YVTLSNNDDGVAHVIEKFMLS 299


>UniRef50_C8P4G9 Cof family protein n=1 Tax=Lactobacillus antri DSM 16041
           RepID=C8P4G9_9LACO
          Length = 274

 Score =  275 bits (705), Expect = 9e-73,   Method: Composition-based stats.
 Identities = 57/274 (20%), Positives = 107/274 (39%), Gaps = 12/274 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            ++VA D+DGTL++    ++P     +K  + +G+  V  TGR    V      L +   
Sbjct: 3   IKMVAIDIDGTLINDQREITPKTVAAIKKASQQGVKIVLCTGRPMTGVRAYLKQLGLNNR 62

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y+++ NG       G ++   +L  +  +D          + + +   D  +     
Sbjct: 63  DDEYVVSFNGGLAQTTSGKVMVDESLSFNDYADWENYCLK-EGVHSQLETRDYIYTTNQD 121

Query: 118 PEEMRFFKEAVFQYAL-----YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
             +   ++  +    +      E   +  + V       D  E +      +      R 
Sbjct: 122 ISKYTVYESELVDMPIRYRPLDEMSRIRDQYVIAKAMMVDEKEVIDRALADLPEELASRF 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           ++  S    LE M  GVSKG AL+ + ++LG    + +A G+  ND  ML  AG G  MG
Sbjct: 182 SIVRSEDFYLEFMRKGVSKGQALDMLCQELGIGASEVMALGNAQNDNSMLEFAGHGVAMG 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           ++ ++   +  +  V   N  D V   + K   +
Sbjct: 242 NSVEKTLAIADD--VTADNNHDGVAAAIDKYVFT 273


>UniRef50_C9AY54 HAD-superfamily hydrolase n=4 Tax=Enterococcus RepID=C9AY54_ENTCA
          Length = 272

 Score =  275 bits (705), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 63/271 (23%), Positives = 111/271 (40%), Gaps = 9/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           M +++A DLDGTLL+    ++P  KE L    A+G+  V  TGR    +    + L +K 
Sbjct: 1   MIKLIAIDLDGTLLNDKKEVTPRNKEVLARAKAQGVKIVICTGRPLRAIRPYLEELSLKE 60

Query: 60  --SYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NG  V  +  G +I    +      +L  V  ++ ++  +V  ++       
Sbjct: 61  PGDYSITFNGGLVQKNETGEIIEKAAMQLADIHELVSVA-EDLNLPLDVVSEEIVLSLPT 119

Query: 117 RPEEMRFFKEAV--FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                  +           +    L+   +          E L P    I++   ++  +
Sbjct: 120 SAAHPSIYGSLNPLLDCRPFAVADLDESMLYNKAVIAYHQEVLDPKIPEISSEIREKYEI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LE M  G++K + +  +A+ LG   ++ +A GD  ND  M+  AG G  M +A
Sbjct: 180 IKSRNNLLEFMPKGITKAYGISLLAQDLGIKQEEVMAIGDEENDLPMIRYAGIGVAMANA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
              +K+      V  +N +D V   + +  L
Sbjct: 240 VPIIKEAAD--VVTVSNQEDGVAAVIEEYVL 268


>UniRef50_B8CYJ2 Cof-like hydrolase n=1 Tax=Halothermothrix orenii H 168
           RepID=B8CYJ2_HALOH
          Length = 267

 Score =  275 bits (705), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 73/266 (27%), Positives = 120/266 (45%), Gaps = 5/266 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++VA DLDGTL+  +  LS    + +  L  RG+  V ATGR  +        L IK  
Sbjct: 4   YRMVAMDLDGTLIDENQNLSQVTIDVITELMNRGVICVIATGRMFISALPYVRKLGIKKP 63

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NGA + D     ++    +  ++A  +  +  +  +   N+Y DD   + R   E 
Sbjct: 64  VITYNGAFIKDPVTNKVLHHKPIPLNLAGQVIKITEEYGN-HINLYEDDRLLVARRNEET 122

Query: 121 MRFFKEAVFQYALYEP-GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
           + +   A  +     P      +  +K+       ++   + + I  +  D + V+ S  
Sbjct: 123 LLYEDIAGVKAREVGPLSDYLGKPPTKLLIIERDRDKYEAIYREIRLQLEDDLAVTRSRD 182

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +E+M   +SKG ALE VA      L   IA GD  ND EM+  AG G  MG++ +++K
Sbjct: 183 IFIEIMGKEISKGKALEKVASGFEIPLSQVIAIGDSWNDLEMIKAAGLGVAMGNSPEQIK 242

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
                  V  +N ++ V   L K+ L
Sbjct: 243 AEADL--VTLSNKENGVARILEKVLL 266


>UniRef50_C9XLD9 Putative hydrolase n=7 Tax=Clostridium difficile RepID=C9XLD9_CLODC
          Length = 273

 Score =  275 bits (705), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 60/273 (21%), Positives = 115/273 (42%), Gaps = 10/273 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGT+L+    ++P   E+++     G   V  TGR    V ++ + L +  
Sbjct: 1   MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGRPLPGVKELLNQLNLTD 60

Query: 61  ---YMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I  NGA + ++    +I    +  D    ++  V        ++           
Sbjct: 61  EGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKKYKTKIHINTMTNLITPNE 120

Query: 117 RPEEMRFFKEAVFQYA---LYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            P +    +  +       + +  + E   + K+    D  E+L  + Q +     ++  
Sbjct: 121 APGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIV-DEPERLEEIIQQLPKNLFNKYT 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +  S    LE +    +KG AL+ +   L   +++ IA GD  ND  M+  AG G  MG+
Sbjct: 180 IVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAVGDEENDQHMIKYAGLGVAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A   +K++     V  TN ++ V   + K  L+
Sbjct: 240 ARNSIKEIAD--YVTDTNNENGVAKVINKYILN 270


>UniRef50_A8MEY7 Cof-like hydrolase n=2 Tax=Alkaliphilus RepID=A8MEY7_ALKOO
          Length = 275

 Score =  275 bits (704), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 66/276 (23%), Positives = 119/276 (43%), Gaps = 17/276 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+ +  ++   +  LK    +GI    ATGR         + L I S 
Sbjct: 3   YKLIVLDMDGTLLNRNKEVTKENQIALKKAQEKGIKVAIATGRVFTSAKFYANMLGIDSP 62

Query: 62  MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR----- 115
           +I  NGA + +     +I+ + + ++       +   +  +  + Y +D  ++       
Sbjct: 63  IIACNGALIKEAASNEIIYTNPIRKEDLLKSLEIFRRH-QVYFHTYDEDTIYIESLGFSS 121

Query: 116 --HRPEEMRFFKEAVFQYALYEPGLL----EPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
             +        +E        E   L     P    K+    +  E++L ++  +   +G
Sbjct: 122 AIYNDWNEDQSEENKIPIKKLEDSYLYFKDNPIETLKIMAVDEDSEKMLQIKTELGEIYG 181

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
             +N   S    LEVM  GVSKG+A+E ++K  G   ++ I+FGD  ND  M S +G   
Sbjct: 182 IELN--KSWYNNLEVMNKGVSKGNAIEMLSKIYGIKREEIISFGDHFNDLSMKSYSGTFV 239

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            MG+A + +K       +  +N +  V   + KL L
Sbjct: 240 AMGNAEEAVKKEA--HYITSSNDESGVAKGIEKLVL 273


>UniRef50_A6LB32 Haloacid dehalogenase-like hydrolase n=23 Tax=Bacteroidales
           RepID=A6LB32_PARD8
          Length = 268

 Score =  275 bits (704), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 65/268 (24%), Positives = 120/268 (44%), Gaps = 7/268 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  DLDGTL +    ++P+ +ETL     +G++ V A+GR    +  + + L IK Y
Sbjct: 3   YKLLVLDLDGTLTNSKKEITPFTRETLLQAQEKGLHLVLASGRPTYGIVPLAEELNIKQY 62

Query: 62  ---MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              +++ NG +V D +   ++F   L  DI   L+    +   +    Y           
Sbjct: 63  GGFILSFNGGKVIDLMTDKVLFEQALPPDIVPVLYNRSKE-AGLAILSYNGKYILSEHPE 121

Query: 118 PEEMRFFK-EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
            + +++       +    +  L +    +         E L+PLE+ +    G R+NV  
Sbjct: 122 NKYVQYESFLTKMKIKATDDFLRDLHQPADKCLVVGEPEMLVPLEEKLRQELGKRINVYR 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE++  G+ K  +L  + ++     ++ IA GDG ND  M+  AG G  M +A  
Sbjct: 182 SEAFYLELVPKGIDKAASLSRLLERTRIKQEEVIAIGDGFNDVSMIHFAGLGVAMANAQP 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +K     +    TN +D V  ++++L 
Sbjct: 242 PVKANADRITQY-TNDEDGVARFIQELL 268


>UniRef50_B0ADP8 Putative uncharacterized protein n=1 Tax=Clostridium bartlettii DSM
           16795 RepID=B0ADP8_9CLOT
          Length = 273

 Score =  274 bits (703), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 69/274 (25%), Positives = 129/274 (47%), Gaps = 16/274 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ SD+DGTLL  +H ++   K  L     +G+  V A+GR +    +  D L+I + 
Sbjct: 3   YKLIVSDMDGTLLGDNHKITEENKIALSKALEKGVKIVPASGRIYNSAREHFDFLDINTP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I  NGA + +     LI+ +N+  DI   +  +   N  +   +Y ++         E+
Sbjct: 63  LIACNGAIIKETKTNKLIYKNNIPNDICLKIIDIFEKNE-VYYQLYSENTMMCKNLSKED 121

Query: 121 MRFFKEAVFQYALYEPGLLEPEG---------VSKVFFTCD-SHEQLLPLEQAINARWGD 170
            R  KE +  +   +  +   +          + K+    D   ++L  +++ ++    +
Sbjct: 122 QRQTKERLKNFFNDDINVHFGDDLKEEVIKHKILKIIAIDDYDMDKLKKVKEDLDQI--E 179

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + ++ S    +E+M  GV+KG AL+A+   LG    + IAFGD  ND  ML +AG G +
Sbjct: 180 DIEITSSWFNNVEIMHKGVNKGEALKALINYLGIDKDEVIAFGDNYNDLPMLELAGIGVV 239

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           MG+A+  +K+      +   N +D V   + K  
Sbjct: 240 MGNANDEVKEKGD--YITAKNTEDGVAKAIYKFL 271


>UniRef50_Q03T33 Predicted hydrolase of the HAD superfamily n=9 Tax=Lactobacillaceae
           RepID=Q03T33_LACBA
          Length = 271

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 65/270 (24%), Positives = 111/270 (41%), Gaps = 8/270 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            +++A D+DGTLL+  + L+    + ++   A+GI  V  TGR    V    D ++I   
Sbjct: 3   IKLIAIDIDGTLLNEKNELAQATIDAVQAAKAQGIKVVLCTGRPLTGVQPYLDAMDIDGD 62

Query: 61  --YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             Y IT NG+    + G ++  H+L  +   DL             +   D  +      
Sbjct: 63  DQYAITFNGSVAQTISGKVLTNHSLTYEDYIDLEAWARK-VRAHFQIETPDYIYTANKDI 121

Query: 119 EEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                 +  + +  +   E      +         D  + +  ++  +   + DR +V  
Sbjct: 122 SAYTIAESYLVRMLIQYREVSETPRDLTISKAMFVDYPQVIEQVKANMPQDFKDRFSVVQ 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    +EVM    SKG  L  +  +LG +  D +  GD  ND  M+  AG G  MG+A  
Sbjct: 182 SAPYFIEVMNRRASKGGTLSELVDQLGLTADDVMTLGDQGNDLTMIKYAGLGVAMGNAID 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +K+      V  TNA++ V   +RK  L+
Sbjct: 242 EVKEAAQA--VTLTNAENGVAAAIRKYALN 269


>UniRef50_C1QE38 HAD-superfamily hydrolase, subfamily IIB n=1 Tax=Brachyspira
           murdochii DSM 12563 RepID=C1QE38_9SPIR
          Length = 269

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 71/263 (26%), Positives = 129/263 (49%), Gaps = 6/263 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A+DLDGT L+ +  +S Y K+  + L   GI  + +TGR    + + ++ +   +Y
Sbjct: 7   IKLIATDLDGTFLNNESEISDYNKKVFQYLMNNGIEIILSTGRPFNGMQRYKNMINNDNY 66

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            I  NGA + D +G  I+   +D   +  +  +VN    +  +VY  +++ ++       
Sbjct: 67  SIVFNGAIIADTNGKFIYNKVIDEASSRGVANLVNKYK-VYLHVYSGNKYIVSEPDFYYE 125

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           R+ ++      +     ++    SK+ F  +  E L  L+  I + +   V+ SFS    
Sbjct: 126 RYIEKENITDTIIGLDNVDNFEFSKMVFIGEREELL-RLQSYITSHF--NVHTSFSHTNF 182

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LEV+A G++KG AL+ +  K G   ++ IAFGD  ND EM+  AG G  M +  + +K  
Sbjct: 183 LEVLANGINKGSALKWLCDKKGIKREEIIAFGDNYNDIEMIEYAGVGVAMYNGEEDVKKK 242

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
                V  +N ++ V  +L K  
Sbjct: 243 AD--YVCLSNDENGVGEFLNKFL 263


>UniRef50_A4BEF7 Hydrolase, haloacid dehalogenase-like family protein n=3
           Tax=Bacteria RepID=A4BEF7_9GAMM
          Length = 314

 Score =  274 bits (701), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 63/266 (23%), Positives = 105/266 (39%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            +++  D+D TLL+  H +S    + ++ ++A+GI    A+GR    +    D L +   
Sbjct: 45  IRMIVMDMDDTLLNDQHQISESNLQAIQRVSAQGITIALASGRPTPAMESYADLLGLTQQ 104

Query: 60  SYMITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y+I+ NGA V D      I+  +L +     L    ++  +   + Y D      RH P
Sbjct: 105 GYVISYNGAYVTDWSTQEQIYECSLTKAECDLLVDAAHEQ-NSDLHTYVDGAIVTTRHNP 163

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
                         L +      +G           EQ+  + Q      GD   +S S 
Sbjct: 164 YTDIESNLTGLPIRLVDSLKAVVQGTVPKVLLVAPPEQVTEMRQIFAKTLGDHFTISISK 223

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LE     V K  A++ +  +LG +    +A GD  ND  ML+  G G  MG+A   +
Sbjct: 224 PYFLEFTNKQVDKSAAIDVLCARLGIAKSSVMAIGDSYNDLTMLTDCGIGVAMGNAPDDI 283

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           K +        +N D  V   + K+ 
Sbjct: 284 KAIANW--TTASNNDHGVALVIDKIL 307


>UniRef50_Q2JQT8 HAD hydrolase, IIB family n=1 Tax=Synechococcus sp. JA-3-3Ab
           RepID=Q2JQT8_SYNJA
          Length = 285

 Score =  273 bits (700), Expect = 4e-72,   Method: Composition-based stats.
 Identities = 65/267 (24%), Positives = 120/267 (44%), Gaps = 7/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGT+  P + +S   ++ ++   A G+    ATGR H    +    +     
Sbjct: 22  IRLLVLDIDGTIAGPSNQVSEPVRQAIQKAKAAGVRVAIATGRMHRSAERFHYAIGADMP 81

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           + +  GA + D D    +   +LD  +A +L  V+ D P +  ++Y DD+ ++    P  
Sbjct: 82  LCSYQGALIRDPDSQKTLKHWSLDWSLAEELLQVLQDQP-VGVHLYIDDQLYLRELSPLS 140

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARW-GDRVNVSFSTL 179
             + + +   + +  P     +  +K+    +  E L  L+ ++  R+  +++ ++ S  
Sbjct: 141 QAYAERSQVPFQMLSPAQH-GKSPTKILAVSEDTEFLQQLQGSLRQRYSPEQIYLTRSEP 199

Query: 180 TCLEVMAGGVSKGHALEAVA-KKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
             LE     V+KG+A+  +A + LG S    +A GDG ND EML  AG G  MG+A   L
Sbjct: 200 IFLEATHAAVNKGNAVRFLAEELLGVSADQVMAIGDGDNDIEMLQYAGIGVAMGNASPAL 259

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
                   V     +D V   +    L
Sbjct: 260 LPHADW--VAPPVTEDGVAVAIETFIL 284


>UniRef50_C9LAG7 HAD hydrolase, IIB family n=1 Tax=Blautia hansenii DSM 20583
           RepID=C9LAG7_RUMHA
          Length = 268

 Score =  273 bits (700), Expect = 4e-72,   Method: Composition-based stats.
 Identities = 62/268 (23%), Positives = 109/268 (40%), Gaps = 7/268 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++  D+DGT+ +    ++   K  +  L  RGI    A+GR    +  +   LE+   
Sbjct: 3   YKLLVLDIDGTVTNSKKEVTEKTKNAILDLQKRGIPVAIASGRAPQGIYSVAKALELDKF 62

Query: 60  -SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRH 116
            SY++  NGAR+ +   G  I++  L   + + L+    +N  I    Y + E     + 
Sbjct: 63  GSYIMPFNGARIVNFQTGECIYSKTLPLHLPARLWRDAVEN-GIGIVTYDEKEVIAGTKP 121

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
               +   K A    A +E      +            E L  LE     ++     +  
Sbjct: 122 DKYTLLEAKIASMPIAYHEDFHTYVDFPVNKCLMTGEPEDLEALEPVFAQKYFHEAQIFR 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE     V K + L+ + + LG   ++ I  GDG ND  M+  AG G  M +A +
Sbjct: 182 SEPYFLEATPKNVDKAYCLKHLLEILGIKREEMICCGDGFNDISMIQYAGLGVAMANAQE 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ++K +   + V   N  D +   + K +
Sbjct: 242 QVKAVADYVTVC-DNDHDGIAEVIEKFF 268


>UniRef50_A0AEX0 Complete genome n=17 Tax=Listeria RepID=A0AEX0_LISW6
          Length = 270

 Score =  273 bits (700), Expect = 4e-72,   Method: Composition-based stats.
 Identities = 68/273 (24%), Positives = 128/273 (46%), Gaps = 11/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY+++A D+DGTLL+  H ++P  ++++K    +G+  V  TGR    + +    L++  
Sbjct: 1   MYKIIAIDIDGTLLNDAHKITPAVRDSIKAAKEKGVKVVLCTGRPLAGIKKSLIELDLLE 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NGA V +      +    L++    +++   +   ++    +     ++   
Sbjct: 61  AGDYAITFNGAVVLETASEKTLADITLNKAELEEIYAFCHA-ENVNVTYFDGKNMYVPSR 119

Query: 117 RPEEMRFFKEAVFQYALY---EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
           +  E+      + Q  LY        +   VSK+    DS E++  + + +     ++  
Sbjct: 120 KITEITCQDSLLLQTPLYHLPVEEAPDSIHVSKIMLL-DSPEKITDVIKKLPDTIKEKFY 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           V  S    LE +  GV+KG AL ++A KLG    + ++ GD  ND  M+  AG G  MG+
Sbjct: 179 VVRSVPYNLEFLQKGVNKGSALASLASKLGVKQSEVMSIGDQENDTTMIEYAGMGVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A + +K++        TN +D V + ++ L L+
Sbjct: 239 ATEHIKEIAN--YTTTTNNEDGVANAIQMLVLN 269


>UniRef50_Q897B3 Putative haloacid dehalogenase-like hydrolase n=1 Tax=Clostridium
           tetani RepID=Q897B3_CLOTE
          Length = 263

 Score =  272 bits (698), Expect = 7e-72,   Method: Composition-based stats.
 Identities = 65/265 (24%), Positives = 132/265 (49%), Gaps = 4/265 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGTLL+ +H +S    +T+K    +GI  +  +GR +         LE K 
Sbjct: 1   MYKLIALDIDGTLLNREHEISDETIDTIKESMDKGIKIILVSGRDYSAAEPYIKKLETKD 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             +  NGA ++D +G +I +  LD++I   +  +  +  DI   ++ ++  ++N      
Sbjct: 61  LFLGLNGANIYDNEGKIIHSEYLDKEIVEYIIELC-EKEDIYIVLFIENNTYVNEISDFM 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                              + + V+K+  T    E+L+P+++ +++++G ++N  FS   
Sbjct: 120 GIDNYVFNSIEVGQISKFYKEQNVTKILLTHK-EEKLIPIKEKLDSKYGSKINSQFSLPQ 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE+  G ++KG AL+ + +K     ++ +A GD  ND  M+  AG G  MG+  + +K+
Sbjct: 179 FLEIFNGKINKGVALKRICEKYKIPKENVMAIGDWDNDITMIKYAGLGIAMGNGSENIKE 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 +  +N ++   + ++K  L
Sbjct: 239 AAD--FITNSNEENGAAYAIKKFVL 261


>UniRef50_UPI0001BC341D haloacid dehalogenase-like hydrolase n=1 Tax=Butyrivibrio crossotus
           DSM 2876 RepID=UPI0001BC341D
          Length = 269

 Score =  272 bits (697), Expect = 9e-72,   Method: Composition-based stats.
 Identities = 59/269 (21%), Positives = 112/269 (41%), Gaps = 8/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++A D+DGTL +    ++   K  +     +G   + A+GR    +    + L +K  
Sbjct: 3   YKILAFDIDGTLTNSQKIITEETKRAIFAAMDKGCKVLIASGRPVKGLRGYAEELHLKEN 62

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NG  +    D  +++   + +    +++ +   +  +    Y+ +        
Sbjct: 63  GGYILSLNGGYIMSCADEKVLYDVKVPKKYYKEIYELSKKH-GVNLLTYQGETVISEDID 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGV-SKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
            E +                L E        F      + L  +E+ +  +  + ++V  
Sbjct: 122 DEYLDIEARLNGLPKKKVDNLYEYLDFEVNKFLMTGDGDYLAEVEKDVYDKLHNNLDVYR 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE++   V+KG ALEA+   LG    + +AFGDG ND  M+  AG G  MG+A  
Sbjct: 182 SEPFFLEILPKDVNKGKALEALLAILGVDRDELMAFGDGYNDKTMVEYAGLGVAMGNAKD 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +K+      V  TN +D +   + K  L
Sbjct: 242 VVKEAAD--YVAPTNDEDGIVEVIHKFIL 268


>UniRef50_A6LB33 Haloacid dehalogenase-like hydrolase n=34 Tax=Bacteria
           RepID=A6LB33_PARD8
          Length = 410

 Score =  270 bits (692), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 64/271 (23%), Positives = 110/271 (40%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+    ++P     L      G++ V A+GR    V  + + LE+  Y
Sbjct: 3   YKLLVLDVDGTLLNDKKEITPRTHAALLKAQQMGVHVVLASGRPTNGVQPLAEALELNHY 62

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              +++ NG ++ +   G L+F   +D  +   L     +N       Y  D    +   
Sbjct: 63  GGFILSYNGGQIINAQTGELMFEKRIDPAMIPYLNRKAKEN-GFAIFTYHKDYILTDSPE 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEG--VSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
            + ++   E      +      E       K   T D    L+ LE     R    +   
Sbjct: 122 NKHVQEEAELNKMRIIGVENFPEAVDFAPCKCILTSDDENNLVGLENHWKKRLDGVLEAF 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LEV    ++KG+ L  + + L  + ++ +A GDG+ D  ML +AG G  MG+A 
Sbjct: 182 RSEDYFLEVAPHFINKGNTLAVLMEMLNITTEEVVAIGDGVADVSMLQLAGTGVAMGNAR 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K          +N  D V   + K  L+
Sbjct: 242 DSVKACAD--FTTLSNNMDGVAVAIEKAILA 270


>UniRef50_A6FJC9 Putative uncharacterized protein n=1 Tax=Moritella sp. PE36
           RepID=A6FJC9_9GAMM
          Length = 263

 Score =  270 bits (692), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 119/265 (44%), Positives = 167/265 (63%), Gaps = 2/265 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+V+ SDLDGTLL+P H +S   K T+  L  +G  F+ ATGRHHVDV  IR  ++ + 
Sbjct: 1   MYKVIVSDLDGTLLTPAHIVSEQTKITIHKLLKQGKKFIIATGRHHVDVEAIRKTIDAEI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGARVH+  G LI++ N+  DIA  +   +N    I  N++RDDEWF+N   PE 
Sbjct: 61  YLITSNGARVHNHKGELIYSKNIATDIA-QMITEINLPETIQANIFRDDEWFVNTPNPEV 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           + F +++ F Y + +   L+  G++K FF C  H+ L+ L   INA++  ++NVSFS   
Sbjct: 120 LNFSQDSTFSYQVVDLEALDKAGIAK-FFFCGPHKDLVALAAQINAQYSTQLNVSFSLPE 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM   V+K  AL  V +  G+++ + +AFGDGMND EML    KG +MG+A   LK 
Sbjct: 179 CLEVMDINVNKAQALAEVLRIKGFTMAETVAFGDGMNDVEMLQAVDKGLVMGNASTMLKA 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P+ E+IG +ADD V  Y+ K  L
Sbjct: 239 TLPDFEIIGDSADDGVAQYIEKYIL 263


>UniRef50_D1PLJ0 Hydrolase n=1 Tax=Subdoligranulum variabile DSM 15176
           RepID=D1PLJ0_9FIRM
          Length = 308

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 61/272 (22%), Positives = 117/272 (43%), Gaps = 12/272 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+V+A DLDGTL + +  ++P  K  L+    RG+  V A+GR  V +  +   LE++ +
Sbjct: 39  YKVLALDLDGTLTNSEKIITPRTKAALQEAARRGVCIVLASGRPTVGIQPLARELELEKF 98

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              +++ NG ++ D   G  +  H    D+   +        +++   Y           
Sbjct: 99  GGCILSYNGGKIIDCKTGKTLVQHAFPPDLIEPVCTFSR-YWNVVPLTYDAGGVVTEHAD 157

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPE---GVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
              ++     + +  + E   L  E    + K+  T D  + +  +E+ +   +  ++++
Sbjct: 158 SPYVQEEAR-INKIPVREVPDLPAEVRYPIHKLLLTGDPAD-MPHVEELMQQEFAGKLSI 215

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    +E M   V K  +L+ + +  G + ++ +A GDG ND  M+  AG G  MG+A
Sbjct: 216 YRSQPFFIETMPLNVEKAASLDLLLRSKGLTAENLMACGDGWNDLPMIRFAGLGVAMGNA 275

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              +K           N  D V   + +  LS
Sbjct: 276 QAPVKAAADCQ--TADNDHDGVGLAVEQYILS 305


>UniRef50_C2EBE1 HAD superfamily hydrolase n=1 Tax=Lactobacillus ruminis ATCC 25644
           RepID=C2EBE1_9LACO
          Length = 288

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 63/272 (23%), Positives = 131/272 (48%), Gaps = 10/272 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++  D+D TLL+ + T++P   E +K    +G+ F   TGR  + V    + L +K 
Sbjct: 18  MYKLIVCDMDETLLADNKTITPKTVEAIKRAVKKGVRFSPNTGRGFLSVQDDLEKLGLKD 77

Query: 61  ----YMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I++NGA +  + +  ++    +  +  ++LF +  ++P+   ++Y  DE ++  
Sbjct: 78  VSGQYVISNNGAVIVENKNNRIVKTETMKFETVNELFKLGIEHPEYCVHIYTPDELYIWN 137

Query: 116 HRPEEMRFFKEAVFQYALYEPG---LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
              EE  +    +  Y   +      L+ + ++K+ F+  S  + L L++ +   + + +
Sbjct: 138 LTDEEFAYIDGRLNDYEQPKDESIEFLKEKQITKIIFSVPSEGERLALQKYVQENF-EEM 196

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           N++FS+   +E  +    KG A   + + LG   ++ IA GD  ND  M+  AG G  + 
Sbjct: 197 NITFSSDRYIEFNSKEADKGQAALHLGELLGIKPEEIIAIGDNGNDVPMIKAAGLGVSVA 256

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +  + +K++   +     N  D V   + K  
Sbjct: 257 NGREFVKEIADYVTEA-DNNHDPVAEVIEKFI 287


>UniRef50_Q8ENE7 Hypothetical conserved protein n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8ENE7_OCEIH
          Length = 246

 Score =  270 bits (691), Expect = 4e-71,   Method: Composition-based stats.
 Identities = 61/263 (23%), Positives = 121/263 (46%), Gaps = 24/263 (9%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGTLL+P+H +S   K+ ++    +GI+ + +TGR         + L + SY+
Sbjct: 8   KLIALDMDGTLLTPEHEVSERNKKAIQTALEQGIDVILSTGRSWDTCFPFAEELSLTSYL 67

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           IT+NG ++  ++  L+  H L  +    ++ +  +       +  +              
Sbjct: 68  ITANGGQIWTVEKELLQQHLLKTETVEKMYLLAKEKNMHCWMISTEK------------- 114

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
                   +  + P  L      K     +   +L  + + ++  + D + ++ S  T +
Sbjct: 115 -------VFRGHAPDNLYDHQWLKFGCASEDKNKLDQMIKELS--YNDELELTNSLPTNI 165

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           E+   GVSK  AL+ + +K+G ++ + +A GD +ND +M+  AG G  MG+A   +K + 
Sbjct: 166 EINPKGVSKAQALQFLCEKIGITMDNVMAVGDSLNDIKMIQEAGVGVAMGNAQVAIKKVA 225

Query: 243 PELEVIGTNADDAVPHYLRKLYL 265
                  TN +D V   + K  L
Sbjct: 226 N--YTTDTNEEDGVGIAIEKYAL 246


>UniRef50_B7HYF7 Hydrolase, haloacid dehalogenase-like family n=81 Tax=Bacillales
           RepID=B7HYF7_BACC7
          Length = 273

 Score =  269 bits (689), Expect = 8e-71,   Method: Composition-based stats.
 Identities = 63/252 (25%), Positives = 111/252 (44%), Gaps = 7/252 (2%)

Query: 18  HTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY---MITSNGARVHDLD 74
           HT+SP  KE L     +G+  V A+GR    +  +   L ++ Y   +++ NGA++ +  
Sbjct: 19  HTISPRTKEALMTAQEQGVKVVLASGRPTFGMRNVAKELRLEEYGSFILSFNGAKIINCK 78

Query: 75  -GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYAL 133
               IF+  L  +I  +LF + +   D+  + Y  D+     + P              +
Sbjct: 79  TNEEIFSSTLSPEIVHNLFEI-SKTEDVWIHTYMGDDIVTEENNPYTEIEGDITGMPIVV 137

Query: 134 YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGH 193
            +      +            E+L+ +E+ +  +   +++V  S    LE    GV+KG 
Sbjct: 138 VDDFKAAVKEPVVKVLMNKEAERLVEVEKKLQKQLEGQLSVMRSKPFFLEFTEAGVTKGT 197

Query: 194 ALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNAD 253
           +L  + +KLG   ++ IA GD  ND  M+  AG G  MG+A   +K++     V  TN +
Sbjct: 198 SLNQLIQKLGIKREEVIAMGDSYNDQAMIEFAGLGVAMGNAPDDIKEIAN--YVTDTNMN 255

Query: 254 DAVPHYLRKLYL 265
           D V   + K  L
Sbjct: 256 DGVAKVVEKFVL 267


>UniRef50_A1SVY5 Cof-like hydrolase n=4 Tax=Bacteria RepID=A1SVY5_PSYIN
          Length = 268

 Score =  269 bits (688), Expect = 9e-71,   Method: Composition-based stats.
 Identities = 58/271 (21%), Positives = 108/271 (39%), Gaps = 8/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY++V  D+DGTLL+    ++   ++ +      GI  V A+GR    +    + L +  
Sbjct: 1   MYKLVVLDMDGTLLNSQKEITERVRKAINAAKDIGIKVVLASGRPIDGMSPALEALSLTT 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYR-DDEWFMNR 115
              Y++T N +   +     +I +  L    A DL+ +      + T+ Y         +
Sbjct: 61  VDDYVLTCNASLTLNAGSREVIRSEFLTGQDARDLYHLSVK-LGVNTHAYSAKQGLITPK 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                         +  + +   LEP+         D  + L      +     ++ +++
Sbjct: 120 TSKYTEHEADINQIKINICDFTTLEPDHEMLKIMMIDEADLLTAAINRLPDSLQEKYSMA 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S     E M+    K + + A+A  LG++ ++ I  GD  ND EM+  AG G  M +A 
Sbjct: 180 QSAPFFYEFMSKKSGKANGVIALAAYLGFTQEEVICVGDAGNDLEMIQYAGLGIAMANAT 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K +     +  +N  D V H   K  L+
Sbjct: 240 DDVKAVAD--YITLSNDQDGVAHVFEKFILA 268


>UniRef50_C3K9U8 Putative haloacid dehalogenase-like hydrolase n=1 Tax=Pseudomonas
           fluorescens SBW25 RepID=C3K9U8_PSEFS
          Length = 274

 Score =  269 bits (688), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 71/266 (26%), Positives = 120/266 (45%), Gaps = 3/266 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + + SD+DGTLL PDH+LS    + ++ L   G+ F  A+GR    +  + +   I   
Sbjct: 9   IRFILSDVDGTLLHPDHSLSQRTADAVRALREAGVLFSLASGRPPKAMLHLIETFGIDVP 68

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR-PEE 120
           +   NG  + + DG+++ AH+L  + A     + +  P++   V+ D +W       P E
Sbjct: 69  VAGFNGGTLINPDGSILVAHHLPAEAALVTLALFSAEPEVEVWVFADGDWLRRDPSGPME 128

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            R      +   + E      + V K+     + + L+ LE  +  +      VS S   
Sbjct: 129 PREANGLGYGPVVVESFEPYLDRVDKIVAASHNTQLLVELEARLQPKVQGLAQVSRSQPV 188

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L+V A   +KG AL+ +A  LG  ++   A GDG ND  M  +AG    MG A + +K 
Sbjct: 189 YLDVTAMLANKGEALKTLAAHLGVPMEQTAAIGDGGNDPAMFQVAGLSIAMGQAEETVKR 248

Query: 241 LHPELEVIGTNADDAVPHYLRKLYLS 266
                 V G+N +D     + +  L+
Sbjct: 249 QA--SVVTGSNIEDGAAEAIERFILA 272


>UniRef50_C5WIM4 HAD superfamily hydrolase n=3 Tax=Streptococcus RepID=C5WIM4_STRDG
          Length = 294

 Score =  269 bits (688), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 65/271 (23%), Positives = 110/271 (40%), Gaps = 8/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M Q++A DLDGTLL+    +     + ++     G+  V  TGR         D L +  
Sbjct: 20  MIQLIAIDLDGTLLNEQKEIPEDNIKMIQEAANTGVKIVVCTGRPQSGTRPYFDQLGLVE 79

Query: 59  KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
           + ++I +NG   +   D  L  + +L+      L  V    P +   +  + ++ +    
Sbjct: 80  EEFLILNNGCSTYSSPDWQLRHSKSLNYSDIEALEQVSQSFPGVYLTLTGEQDYLVLEPE 139

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFF---TCDSHEQLLPLEQAINARWGDRVNV 174
             ++      +    +    L +     +V F          L   E A +       +V
Sbjct: 140 VPDLVQADGDLVFATVQAVSLEQLSQSHQVIFQAMYLGEKAALDAFELAASDHLRQSYHV 199

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LE++  GVSK  AL  + + LG S    +A GD  ND EML+ AG G  MG+A
Sbjct: 200 VRSQDNILEILPKGVSKASALRELVEDLGLSADQVMAIGDAPNDIEMLNYAGLGVAMGNA 259

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            + +K L  ++ V   N +  V   + +  L
Sbjct: 260 SEAIKRLADQVTVT--NDEAGVAQAIHQFVL 288


>UniRef50_C1I280 HAD hydrolase n=1 Tax=Clostridium sp. 7_2_43FAA RepID=C1I280_9CLOT
          Length = 280

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 67/278 (24%), Positives = 115/278 (41%), Gaps = 17/278 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGTLL+  H +S   KE LK   + G+     TGR         D + I S 
Sbjct: 5   IKLICIDMDGTLLNSKHEISERNKEALKKANSLGVKIAITTGRLFCSARYYADLIGIDSP 64

Query: 62  MITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I SNGA +     ++ I  + + ++IA +++ +V  +  +  N    D        P  
Sbjct: 65  VIGSNGAYIKHKYDDIAILENPIPKNIAIEIYKIVKKH-GLTVNFNSWDTLIREDEVPAT 123

Query: 121 MRFF-----------KEAVFQYALYEPGLLEPEGVSKVFFT--CDSHEQLLPLEQAINAR 167
             +             + +    + E        + K       ++ + L   +  +   
Sbjct: 124 HAYTIMNKDLPDDKKVKFIVNSDVIETINNFDGKILKGIVIEEAENKDNLWAAKDELKET 183

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
           +GDR++V  S     EVM G  SKG+A+  +A     + ++ +  GD  ND  ML  AG 
Sbjct: 184 FGDRLHVVSSGTDNFEVMVGTTSKGNAVAHLADTFNINPEEVMCIGDSENDISMLKFAGV 243

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
              MG+  Q +KD+     V  TN +D V   +    L
Sbjct: 244 SVAMGNGLQMVKDIAD--FVTDTNNNDGVAKAIEMFVL 279


>UniRef50_Q0TQ35 HAD hydrolase, IIB family n=9 Tax=Clostridium perfringens
           RepID=Q0TQ35_CLOP1
          Length = 276

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 73/277 (26%), Positives = 122/277 (44%), Gaps = 17/277 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V  D+DGTLL   H +S   KE LK    +G++   +TGR         + + + + 
Sbjct: 3   YKLVCIDMDGTLLDSHHKVSERNKEALKKAIEKGVHIAISTGRVFPSARIYGNIIGVNAP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I SNG+ + D +   +IF   LDR+    +  ++N    +   V   D    +   PE+
Sbjct: 63  LICSNGSYIKDKNTDEVIFKSTLDRETYFKICDIINKYKFLAY-VDSTDGLIADTDIPED 121

Query: 121 MRF-------FKEAVFQYALYEPG----LLEPEGVSKVFFT-CDSHEQLLPLEQAINARW 168
                      ++   ++   +          E + K      +    +   ++   A  
Sbjct: 122 DSHRLMNSWVDEKEKIKFYNCDDLRDAYDEHGEDILKFIIIKQEGGPNIEEAKEEFEALE 181

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
           G  + V  S   C+E+M  G SKG A++A+A KLG SL++ I  GD  ND  ML  AG  
Sbjct: 182 GVDL-VYASWGGCIEIMKKGTSKGSAVKALADKLGISLEEVICIGDSGNDVSMLEEAGLS 240

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +MG+A   +K+      +  TN +D V   + K  L
Sbjct: 241 VVMGNAPDFIKEYGD--YITDTNENDGVAKAIEKFIL 275


>UniRef50_C9XMM6 Putative hydrolase n=4 Tax=Clostridium difficile RepID=C9XMM6_CLODC
          Length = 284

 Score =  268 bits (687), Expect = 1e-70,   Method: Composition-based stats.
 Identities = 71/279 (25%), Positives = 127/279 (45%), Gaps = 21/279 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ +D+DGTLL  +H ++   K  L+ +   GIN   ATGR         D L+    
Sbjct: 3   YKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATGRAFDSAKCNVDFLKEDMP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I  NG+ + + +GN+I+++ +D     ++  V++   DI       D     ++R   +
Sbjct: 63  IIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKY-DIYYQCNSIDSMLYEKNRRTIL 121

Query: 122 RFFKE-------------AVFQYALYEPGLLE--PEGVSKVFFTCD-SHEQLLPLEQAIN 165
            F K+             +  +  + +    E   + + K     + +   L  + + + 
Sbjct: 122 CFTKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPSILDEIRKELR 181

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
              G  + ++ S    +EVM  GV KG+A++ +A+K+    +D IAFGD  ND EM+  A
Sbjct: 182 KVQG--IKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDNYNDIEMIKFA 239

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G G  MG+A + +K       V  TN D  V   + K  
Sbjct: 240 GLGVAMGNAEELIKQEAD--YVTDTNQDSGVAKAIYKFL 276


>UniRef50_A1V919 HAD hydrolase, IIB family n=56 Tax=Betaproteobacteria
           RepID=A1V919_BURMS
          Length = 273

 Score =  268 bits (686), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 101/266 (37%), Positives = 155/266 (58%), Gaps = 3/266 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ +A+DLDGTLL+ DH L PY  +T++ L   G+ FV ATGRH+ DV  IRD L I+ 
Sbjct: 1   MYKAIATDLDGTLLNSDHQLDPYTIDTVRRLAGSGVPFVIATGRHYADVAGIRDLLGIRP 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLF--GVVNDNPDIITNVYRDDEWFMNRHRP 118
           Y+ITSNGARVH  D   I A ++  D    L    +V  +  +I N++ +D W ++R  P
Sbjct: 61  YLITSNGARVHGPDDTRIHAQDVPADAVRQLVRPELVGTHGRVIVNLFTNDGWLIDRDAP 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           + + F +++ F+Y + +    +   ++KV +  +  + L  +   +  R+GD + V++S 
Sbjct: 121 QLLAFHQDSGFRYEIVDMLAHDGADIAKVLYIGEPED-LAVVSGNLARRFGDALYVTYSL 179

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
             CLEVM   VSKG AL  V ++LG     C+AFGD MND ++L  AG   +M +A+  L
Sbjct: 180 PDCLEVMTANVSKGRALRVVLERLGVDPAHCVAFGDNMNDIDLLETAGYPFMMNNANPDL 239

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
               P++  IG N +  V  +LR L+
Sbjct: 240 ALRLPKVPRIGNNFEAGVARHLRALF 265


>UniRef50_C6PMT7 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PMT7_9CLOT
          Length = 267

 Score =  267 bits (685), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 63/271 (23%), Positives = 114/271 (42%), Gaps = 10/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A D+DGTLL+ +  +S   KE ++    +G+N V  +GR    V    D + ++ 
Sbjct: 1   MYKLLAVDMDGTLLNSNRIISKANKEAIRKAVEKGVNVVITSGRGLKGVDNFLDEVHLRG 60

Query: 61  ---YMITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I +NG  ++       +    L          +      +    Y  +       
Sbjct: 61  ENQYLIANNGGTIYRTSNFECVAYKGLRGRDLIKAHTLSKKF-GLNMIAYTHEGPIAAEE 119

Query: 117 RPEEMRFFKEAVFQYALYEP--GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                   +       +      + + + ++K+ F   + E L      +  ++    NV
Sbjct: 120 SEFTRFEAEYVGTPVKIINFKSDIEDNDEITKILF-SQTEELLDKKMLELPKKFYTEYNV 178

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             +    LEVM    +KG+ ++ +A KLG   ++ +  GD  ND EML+ AG G  MG+A
Sbjct: 179 VKTMPIILEVMNKNCNKGYGVKVLADKLGIKKEEVMCIGDQANDVEMLTYAGLGVAMGNA 238

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            + LKD+     V   N +D V   ++K  L
Sbjct: 239 IEELKDIA--QYVTLDNDNDGVAKAIKKFIL 267


>UniRef50_C5RAW2 HAD superfamily hydrolase n=1 Tax=Weissella paramesenteroides ATCC
           33313 RepID=C5RAW2_WEIPA
          Length = 278

 Score =  267 bits (685), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 60/271 (22%), Positives = 107/271 (39%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++  D+D TL++ +  ++P  K+ L+  T +G+  V ATGR    V      L +   
Sbjct: 3   IKLITIDIDDTLVNSEKQITPRVKQALQTATNQGVKVVLATGRPLSGVQDYLTQLHLANQ 62

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              + IT NG+ V    G  +  H L        F  + +  +    V            
Sbjct: 63  SDQFAITYNGSVVQTTAGEQLGGHELSLADYKK-FKAIAEKYNSYIQVESLSYAITANTM 121

Query: 118 PEEMRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                  +  + +  L       +  +     F   D  E++  L + +     D   + 
Sbjct: 122 VNRFANGENNMVRMPLKFQPVSDMTTDEHYVKFMFIDEAEKIDELAEHMPQELKDEYYIV 181

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            ST   LEVM    +KG+ L+ +A KLG  + + +A GD  ND  M++ +G G  M +A 
Sbjct: 182 KSTPNFLEVMHKQSTKGNGLQLLADKLGIDMSETMALGDQHNDLTMIAASGIGVAMANAV 241

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K     +    +  +D V   + K  L+
Sbjct: 242 PEVKATADVM--TTSQNEDGVGLAVEKWVLN 270


>UniRef50_C6IVB2 Predicted protein n=3 Tax=Bacillales RepID=C6IVB2_9BACL
          Length = 267

 Score =  267 bits (685), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 60/268 (22%), Positives = 110/268 (41%), Gaps = 9/268 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+DGTLL+ DH L+P   ET++ +  +G  FV  TGR           + +  Y
Sbjct: 3   YKLIALDVDGTLLTDDHVLTPGTIETIRAIAEQGTEFVLCTGRAPRSSIPYMREIGLDGY 62

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH---R 117
           +I  NGA   D+    ++    ++             + ++  +V      ++       
Sbjct: 63  VICHNGAATVDVRTEEVVHEFAMNPHGLEPYMEYCRKH-NVHFDVNTTFALYVENLAGLT 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
            E +  + +   +           + + K        E+L  +    +  W    N+  S
Sbjct: 122 QETLDVYHQFFMEPEDMPAWADFTKPIVKFTAAGG-MEELDRVYADWSQ-WTQEFNMLRS 179

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               +++M    SKG AL  +A+K G   ++ +A G+  ND  ML+ AG G  M ++   
Sbjct: 180 GDFFIDLMHKDASKGAALRKLAEKRGIPAENVMAIGNYYNDITMLTYAGLGVAMDNSPLD 239

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +K       V  +N ++ V   L K  L
Sbjct: 240 VKAAADA--VTASNNEEGVKRALEKYCL 265


>UniRef50_B6XF55 Putative uncharacterized protein n=2 Tax=Providencia
           RepID=B6XF55_9ENTR
          Length = 269

 Score =  267 bits (684), Expect = 3e-70,   Method: Composition-based stats.
 Identities = 63/270 (23%), Positives = 110/270 (40%), Gaps = 11/270 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            ++VA DLDGTLL+  H +SP  KE +     +G+  V A+GR +  +      L + + 
Sbjct: 3   IKLVAIDLDGTLLNSQHQISPVVKEAITRAHEQGVRIVLASGRPYSGIQPYLQELGLDTA 62

Query: 61  --YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y I++NG+ +H   DG+ ++ + LD         + + N  +  +   D+  F     
Sbjct: 63  NNYCISNNGSVIHQANDGSHLYENLLDFADYQYFAELAS-NVGVHMHALADNTMFTANRH 121

Query: 118 PEEMRFFKEAVFQYALY---EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                     +    L       +      +K+    D  E+L      I     +  ++
Sbjct: 122 ISRYTIHDAYITNTPLVYCPVNEMESSLSFTKIMMI-DHPEKLDVGISYIPENTFENYSL 180

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             ++   LE+     SKG AL+ +  KL  +    ++ GD  ND  ML  +     MG+A
Sbjct: 181 IKTSPYFLEISNKDASKGSALKVLCDKLALTPDKVMSIGDQNNDVTMLQYSSVSVAMGNA 240

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
              ++++     V  TN  D V   L K  
Sbjct: 241 APHIREI--VKFVTSTNDCDGVAVALNKFI 268


>UniRef50_UPI000197CA00 hypothetical protein PretD1_00540 n=1 Tax=Providencia rettgeri DSM
           1131 RepID=UPI000197CA00
          Length = 270

 Score =  267 bits (683), Expect = 4e-70,   Method: Composition-based stats.
 Identities = 67/270 (24%), Positives = 114/270 (42%), Gaps = 11/270 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            ++VA DLDGTLL+  H +SP  KE +     +G++ + A+GR    +      L++   
Sbjct: 3   IKLVAIDLDGTLLNSQHQISPVVKEAITQAKQKGVHIILASGRPFSGISPYLRELDLNTA 62

Query: 59  KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
            +Y I++NG+ +H   DG+ +  + LD       F  +  N  +  +   D+  F     
Sbjct: 63  DNYCISNNGSVIHQANDGSHLAENLLDFADF-QYFEELARNVGVHMHALADNSMFTANRH 121

Query: 118 PEEMRFFKEAVFQYALY---EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                     +    L       +      +K     D  E+L      I     D  ++
Sbjct: 122 ISHYTVADAYLTHTPLIYCPVNEMDSSLEFTKFMII-DHPEKLDMGISYIPENVFDNYSL 180

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           + ++   LEV     SKG ALE + +KLG +    ++ GD  ND +ML  A     MG+A
Sbjct: 181 TRTSPYFLEVSNKTSSKGAALECICEKLGITPDKVMSIGDQNNDIQMLQYASVSVAMGNA 240

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            + ++ +     V  TN +D V   + K  
Sbjct: 241 LEPIRQM--VKFVTTTNDEDGVAVAINKFI 268


>UniRef50_A6P2T9 Putative uncharacterized protein n=1 Tax=Bacteroides capillosus
           ATCC 29799 RepID=A6P2T9_9BACE
          Length = 274

 Score =  266 bits (682), Expect = 5e-70,   Method: Composition-based stats.
 Identities = 73/277 (26%), Positives = 124/277 (44%), Gaps = 18/277 (6%)

Query: 1   MYQVVASDLDGTLLSPDH-TLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK 59
           M +++A D+DGTLL+ DH T+S    + L+    +GI  V ++GR    +  I D + + 
Sbjct: 1   MIKLIAMDMDGTLLNDDHATVSQRNVDALRRAAEQGIEVVISSGRPWSLLQDIADRVGVV 60

Query: 60  SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH-- 116
            YM+TSNGA V D   G  +    + ++       ++         ++ + + ++ +   
Sbjct: 61  RYMVTSNGASVLDQKTGEWLLQIGMPKEQVLKFVEILTRY-HAGFEIFCEGQDYIEQRHM 119

Query: 117 --------RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARW 168
                    PE +  FK  V       P ++E + V K++           +E+ + A  
Sbjct: 120 ETVVREALSPEYVDTFKRRVVVVDDLRP-IIEEKLVEKIYVFYVEPGTREKIEEELRAAG 178

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
                 ++S    +E+ A GV KG AL+ + +KLG    + +AFGD  ND  MLS AG  
Sbjct: 179 PYESACAYS--FNMEITAPGVDKGEALKVLCEKLGIDASEVMAFGDADNDLGMLSWAGWS 236

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             MG+   + K       V G N+D  V   + +  L
Sbjct: 237 FAMGNGTDKAKAAAK--YVTGRNSDSGVAQGVEQYAL 271


>UniRef50_C6VK79 HAD superfamily hydrolase n=17 Tax=Lactobacillus RepID=C6VK79_LACPJ
          Length = 271

 Score =  265 bits (680), Expect = 7e-70,   Method: Composition-based stats.
 Identities = 64/270 (23%), Positives = 102/270 (37%), Gaps = 7/270 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++A D+D TLL     L P     +K    +GI  V  TGR         D L +   
Sbjct: 3   IKLIAIDIDDTLLDSKGQLLPSTIAAVKEAHDQGIKVVLCTGRPLAGAQHYLDALGLAGD 62

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             Y+IT NGA +  + G ++  H +D      L      +      +  D   +      
Sbjct: 63  DQYVITYNGAVIESIAGRIVAKHLVDNAHYRQLTAFGKQHHVPFNVLDADSTIYTADRDV 122

Query: 119 EEMRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             +   +  E      + +P  L  +             QL  +E  +   +G  + V  
Sbjct: 123 NWVTVVQAWENKAGLLIRDPDDLPADFQIAKGVFVGEGPQLDAVEAQVKTTFGRDLYVVR 182

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           +    LE+M  GV+KG A++ +A  L     + +A GD  ND  M + AG    MG+   
Sbjct: 183 AATNFLELMHIGVNKGQAVQDLAAALEIQPDEVMALGDEQNDLPMFAFAGTAVAMGNGSD 242

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             K       V  TN  + V   +R+  LS
Sbjct: 243 IAKAHADH--VTATNDANGVAAAIRQWALS 270


>UniRef50_C7HV82 HAD phosphatase superfamily protein n=1 Tax=Anaerococcus vaginalis
           ATCC 51170 RepID=C7HV82_9FIRM
          Length = 278

 Score =  265 bits (680), Expect = 8e-70,   Method: Composition-based stats.
 Identities = 66/271 (24%), Positives = 120/271 (44%), Gaps = 7/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTLL+    ++   K  L      G   V A+GR  + V    D LE + 
Sbjct: 8   MKKIIAVDIDGTLLNSKRQITEKTKNALIKAQELGHIVVIASGRDPLGVYPFADILEFEK 67

Query: 61  Y--MIT-SNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           Y  +I+  NG R+ +     +I  H +D D+A ++      N  +   +Y +D+   +  
Sbjct: 68  YGGLISNFNGGRITNYKTKDVIINHPMDFDLAKEILQFSEKNLFMHYIIYTEDKIITSSS 127

Query: 117 RPEEMRFF-KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           +  ++    ++A   Y + +      +              +    + +  ++ ++    
Sbjct: 128 KTYKLEEICQKAFTHYEVIDDLAYSLDFAPNKILFSQDPNLIDDDAKKLMDKFSNKTTQV 187

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            ST    E+M  G+ KG +L  +AK     +KD IAFGD  ND  M+ MAG G +M +  
Sbjct: 188 KSTPYFYEIMPKGIGKGESLVEIAKYFDMDMKDVIAFGDEENDQTMIEMAGLGVVMENGA 247

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K+      +  +N DD + +YL K   +
Sbjct: 248 NFMKEKAD--FITKSNDDDGIAYYLEKFVFN 276


>UniRef50_B4SM39 Cof-like hydrolase n=4 Tax=Bacteria RepID=B4SM39_STRM5
          Length = 277

 Score =  265 bits (680), Expect = 8e-70,   Method: Composition-based stats.
 Identities = 64/271 (23%), Positives = 101/271 (37%), Gaps = 11/271 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            ++VA D+DGTLL P HTL+  AK+ +    A G++ V  +GR    +      L I   
Sbjct: 10  IELVAIDMDGTLLDPTHTLTVRAKQAIAQARALGVHIVLTSGRPVPGLAPFLHELGITGD 69

Query: 59  KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y I  NG  V  +     +  + L  D       V  D   +          +     
Sbjct: 70  DDYCIACNGGLVQRIGTRETVVEYPLSFDNFLFCEQVARD-LGVHFQALDSRRMYTPNQD 128

Query: 118 PEEMRFFKEAVFQYAL---YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
                     + +  L       +       K+    D+ + L      + +   +R  V
Sbjct: 129 ISYYTVADSHLSRMPLSYRRVEDMDPSMSFIKLMMI-DAPDVLDAAIARLPSELTERFAV 187

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LEV      KG +L+ +A+ LG    + +A GD  ND  ML  AG    MG+A
Sbjct: 188 LKSAPFFLEVFDHRAGKGPSLQKLAEHLGIDRANVMAIGDQENDLTMLQYAGTSVAMGNA 247

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
              +K +        +NAD+ V   + +  L
Sbjct: 248 IDAVKAVA--RFETTSNADEGVARAIERFVL 276


>UniRef50_C9R7C9 Cof protein n=1 Tax=Aggregatibacter actinomycetemcomitans D11S-1
           RepID=C9R7C9_AGGAD
          Length = 391

 Score =  265 bits (679), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 62/263 (23%), Positives = 116/263 (44%), Gaps = 6/263 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+ V SD+DGTLL+  H ++   ++ +K +  RGI F+  + R    +    + L  +  
Sbjct: 133 YKAVFSDIDGTLLNNQHQITLKTEDAIKNMLKRGIPFIPVSARPPYAITPYTEQLGAQHG 192

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           MI  +GA + D +   +++  L+      L  ++ D   +  + Y   +WF N    + +
Sbjct: 193 MICYSGALILDKNLTALYSVILEPQDLQKLNELLADFAHLSISYYAGLDWFCNDVNNDWI 252

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
           +         A   P  L    V K+       +++  +E  +     + +++  S    
Sbjct: 253 KQESAITGLTAAAMPDNL--TEVHKLLIMG-DADEIQAVEPVLKQALPN-LSIHRSKNEY 308

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+M    +K  A++ + + LG +    IAFGD  ND +ML  AG    MG+A   +K  
Sbjct: 309 LEIMNAAATKAKAIQFMEQYLGITADQVIAFGDNFNDLDMLQYAGLSVAMGNAPDAVKQA 368

Query: 242 HPELEVIGTNADDAVPHYLRKLY 264
               EV   N +  +   L +++
Sbjct: 369 AK--EVTANNNEGGIALVLNRVF 389


>UniRef50_C6VMV1 HAD superfamily hydrolase n=10 Tax=Lactobacillales
           RepID=C6VMV1_LACPJ
          Length = 272

 Score =  265 bits (678), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 60/268 (22%), Positives = 109/268 (40%), Gaps = 12/268 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            +++A D+DGTL++    ++   K+ +K+   + I  V  TGR    V  +   LE+ + 
Sbjct: 5   IKMIAIDIDGTLVNSKKQVTLRVKQAIKMAKEKKIKVVICTGRPLTGVKALLQELELDAQ 64

Query: 61  ---YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y++   GA  +   G LI    +  +   DL  +      +  +   +D  +     
Sbjct: 65  DDQYVVCFGGAATYTTSGELIDERPISYEDYIDLEALARK-LRLHFHAVSEDRLYTADRN 123

Query: 118 PEEMRFFKEAVFQ--YALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQ--AINARWGDRVN 173
             +   ++  +     +   P  +    + K     D  E L    +   +      +V 
Sbjct: 124 IGDYTLYEANLVSMGISYRTPEEMRNIKLIK-SMYVDEPEVLDAAIKQQKLFEPLKKQVT 182

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
            + S     E  A GVSKG+AL+ + +KL  +  + +A GD  ND  M+  AG G  MG+
Sbjct: 183 FTKSAPFYYEANANGVSKGNALQVLCEKLSLTAANVMAIGDEANDLSMIKFAGHGVAMGN 242

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLR 261
           A   +K +    E+   N  D V   + 
Sbjct: 243 AIPEVKQVAD--EITVDNEHDGVAKAIE 268


>UniRef50_A6LQL6 Cof-like hydrolase n=1 Tax=Clostridium beijerinckii NCIMB 8052
           RepID=A6LQL6_CLOB8
          Length = 270

 Score =  265 bits (678), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 68/272 (25%), Positives = 128/272 (47%), Gaps = 14/272 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKL-LTARGINFVFATGRHHVDVGQIRDNLEIKS 60
            ++V  D+DGTLL+ +H ++   K T+      + I  +  + R    +  +++ L I+ 
Sbjct: 4   IRMVCLDIDGTLLNSNHEVTEKVKSTINKVANNKKIPVILVSARMPKGIRFLQEELGIEE 63

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            +I  +GA + D D +++    +D      ++ + ++N +I  ++Y+DDEW++ +     
Sbjct: 64  PIICYSGALILDKDNSVLAREAIDVSNFEKIYKLTSEN-NIHMSLYKDDEWYIEKLDYWA 122

Query: 121 MRFFKEAVFQYALYEPGLL------EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
            +  +       + +   L      E  G SK+    +  E +  L++ I   + + +N+
Sbjct: 123 KQESEITNIIPNIIDFNKLIEQWKREGVGPSKILCMSNPKE-INFLKENI---YDNDLNI 178

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S  T LE+M    SK  A+  + KK      + IA GD  ND +ML  AG G  MG+A
Sbjct: 179 YPSKPTYLEIMPIKASKTSAITCLQKKFSIDKSEIIAMGDNYNDIDMLEYAGVGVAMGNA 238

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            + +K    +  V  TN +D V   L K  ++
Sbjct: 239 PEDVKKHADD--VTLTNDEDGVAEALIKYVIN 268


>UniRef50_D1XVB8 Cof-like hydrolase n=1 Tax=Prevotella bivia JCVIHMP010
           RepID=D1XVB8_9BACT
          Length = 292

 Score =  264 bits (677), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 58/270 (21%), Positives = 107/270 (39%), Gaps = 9/270 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++  DLDGTL +    ++P  KE L     +G+  V A+GR    +  + + L +   
Sbjct: 26  YKMIVLDLDGTLTNSKKVITPKTKEALIQAQKKGVRIVLASGRPTYGIKNLAEELCLNQH 85

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y++  NG ++ D  +   +F   L  ++   L+        +    Y+          
Sbjct: 86  HGYILAFNGGKIIDCSNNETLFEQTLSPELVPTLYNSAMK-GGMQILTYQGKGIAATSTE 144

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPE--GVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
            + ++                LE     ++K     D    L  +E  +      +++V 
Sbjct: 145 DKYVKEEAFINKLPITLYSNFLEQIVYPINKCLIVGDPTP-LHEVEIQLAKTLEGKMSVY 203

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE +   V K  +L  + K  G   ++ IA GDG ND  M+  AG G  M +A+
Sbjct: 204 RSADYFLECVPLNVDKAQSLAKLLKLTGIKREEIIACGDGYNDLSMICFAGLGVAMANAN 263

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           + ++     + +  +N  D V   + K  L
Sbjct: 264 EDIRIQANYVTLA-SNEKDGVAEVVEKFLL 292


>UniRef50_C5NXD6 Phosphatase YidA n=1 Tax=Gemella haemolysans ATCC 10379
           RepID=C5NXD6_9BACL
          Length = 270

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 63/269 (23%), Positives = 126/269 (46%), Gaps = 7/269 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++V +D+D TLL+ D  +S   +E ++    + I  + A+GR    +  I ++L++ S
Sbjct: 1   MIKLVVTDIDDTLLNSDREISKKNREVIEECKKQDIKVILASGRPDFGMMSIVEDLQLDS 60

Query: 61  Y---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           Y   +++ NGAR+ +L    +I+   L  +    L  V  +N +     Y+  +   NR 
Sbjct: 61  YDNYLLSFNGARIANLKTNEVIYEKFLSPERIKFLIDVALEN-NCDILTYQGGKVLTNRD 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                        +  + E    + +  +         ++ + ++  +    GD   V+ 
Sbjct: 120 NEYARIESGLVSAELVISENMKDDIKEGAAKVIILKHPDEAVAVKDKLALELGDEYEVAM 179

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    +E+   G+SKG +L+++ KKLG + ++ +A GDG+ND  M+  AG G  + +A+ 
Sbjct: 180 SKPFFIELNDKGISKGVSLDSLCKKLGLTNENVMALGDGLNDLSMIEFAGMGVAVDNANP 239

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            LK+      +  +N +D   + + K  L
Sbjct: 240 TLKEAAN--FISKSNDEDGFAYAIEKFVL 266


>UniRef50_C2D902 HAD family hydrolase n=1 Tax=Atopobium vaginae DSM 15829
           RepID=C2D902_9ACTN
          Length = 292

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 66/275 (24%), Positives = 113/275 (41%), Gaps = 11/275 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLE--- 57
           MY++VA DLD TLL+    +    +  ++   A+G+  V ++GR    +  I D +    
Sbjct: 19  MYKLVAVDLDETLLNDARHVPLRVRRAIEQARAKGVYIVPSSGRSFAIMQYILDEIGAKD 78

Query: 58  -IKSYMITSNGARVHDLDGNLIF--AHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN 114
               Y I+ NGA + +   N I         D  + ++       ++  +VY     +  
Sbjct: 79  MKDEYAISCNGACITENAHNTIIDLQPPTPWDFCNKIWKHGIQLGNVGVHVYTLASIYTT 138

Query: 115 RHRPEEMRFFKEAVFQYALY---EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
           + R ++   F                 L    + K+ +  +    L  L   +     D 
Sbjct: 139 KWRDDDRNIFTLTGIPAIETREANLEFLRNTHIVKILYMNNDFAYLQQLAHDMRDLTRD- 197

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           V V+FS+   +E    G+SKG AL+ +A  LG  + + IA GD  ND+EM+  AG G  M
Sbjct: 198 VGVTFSSNCYMEFTPKGISKGAALKRLAHHLGIDMSETIAVGDSANDSEMIKAAGLGVCM 257

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            +A   +K     +     N +  V   + K  L+
Sbjct: 258 ANADDSMKAQADYVTQ-NNNNEGGVAEVIEKFILN 291


>UniRef50_B2A708 Cof-like hydrolase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF
           RepID=B2A708_NATTJ
          Length = 278

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 58/271 (21%), Positives = 108/271 (39%), Gaps = 8/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ VA D+D TL++ +  ++   KE++K     G+    ATGR           L +  
Sbjct: 1   MYRFVAIDIDDTLINNELDITEANKESIKAAINHGVLVTLATGRMFKSALPYAKELGLDL 60

Query: 61  YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +IT +GA +     G +++   +  +    +  +  +   +  N+Y DDE  +      
Sbjct: 61  PLITYHGALIKTAVKGEVLYHKPVPLETTLQVVRLAKEKE-LHLNLYIDDELIVEEENKY 119

Query: 120 EMRFFKEAVFQYALYEPGL----LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
              + K A                 P  +        S + +  L    N  +G  + V+
Sbjct: 120 TDYYTKIAGVSLNPVGDLENYLKQYPHKIPTKLTVVASEQMVKRLNYEFNQFFGQDLLVT 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    LE+     +KG A+  +A+         +A GD +ND  M+  AG G  + +A 
Sbjct: 180 ESKSDFLELTHPEANKGDAVAKLAEIYNIPQSKTMAIGDSLNDISMIKTAGMGVAVENAR 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            ++KD+     ++  N +  V   + +  LS
Sbjct: 240 SKVKDVAD--TIVSANDESGVSEAIERFVLS 268


>UniRef50_C7TGI6 Hydrolase of the HAD superfamily n=9 Tax=Lactobacillus
           RepID=C7TGI6_LACRL
          Length = 275

 Score =  264 bits (676), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 73/271 (26%), Positives = 103/271 (38%), Gaps = 10/271 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A DLD TLL+    LSP   E L+   A GI  V  TGR    V    D L +  
Sbjct: 4   MIRLIAVDLDDTLLNSHKQLSPATVEGLQTALASGIKVVPCTGRPLPGVRTTLDALGLHG 63

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDN--PDIITNVYRD-DEWFMN 114
              Y+I   G  V    G +I    ++     D            I +NV     + +  
Sbjct: 64  DDQYVIVQGGGVVQSTSGKIIAQKFMNHQDYKDFSTFATSVSAAGIDSNVLTPAGDVYTA 123

Query: 115 RHRPEEMRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
                     +  E      + EP  +  + V          EQ+  ++    A +G+R 
Sbjct: 124 DRNISRYTVLQAWENHAGIKVREPQEMPDDFVIAKGILLGEPEQVANIQPQAEAEFGNRF 183

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            V  S    LE+M  GV KG  L  + + LG    D IAFGD  ND +M   AG    M 
Sbjct: 184 TVIRSMPFMLEIMPQGVDKGWGLAQLTQHLGLKPADVIAFGDEHNDLDMFDFAGVSVAMA 243

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           +    +K       V  +N DD V   L+  
Sbjct: 244 NGQNVVKSHAD--YVTASNDDDGVVKALKHF 272


>UniRef50_C2BEV0 HAD superfamily hydrolase n=1 Tax=Anaerococcus lactolyticus ATCC
           51172 RepID=C2BEV0_9FIRM
          Length = 272

 Score =  263 bits (675), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 65/271 (23%), Positives = 115/271 (42%), Gaps = 8/271 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTL++ +  ++   +E L   +  G   +  +GR    + +    L    
Sbjct: 1   MKKLIAVDVDGTLVNSEGVITARTREALIAASKAGHEVMIVSGRPTYGLREQAKALAFDE 60

Query: 61  Y---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR- 115
           +   + + NG +++D     ++  H +D D+A ++        D+I  V   +  F +  
Sbjct: 61  FGGILSSYNGGQLYDFKADTILVNHPMDFDLAKEILEFSKS-LDLILMVPHGEVIFTDDA 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                 R       +           +            ++L      I  ++GDR    
Sbjct: 120 ENFYSSRESGMLKMEVRGVRDIRDSLDFAPNKLLFAQDPDKLDAPCANIREKFGDRTEQV 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S     EVM  G+SKG ++    K  G  +KD I FGD MND  M  +AG G  MG+A 
Sbjct: 180 KSARFYYEVMPMGLSKGSSIIEACKIFGIDIKDTIVFGDEMNDMSMFEVAGTGVAMGNAV 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           + +K++     V  TN +D + +YL K  L+
Sbjct: 240 EPVKNVAD--FVTKTNNEDGIAYYLEKFVLN 268


>UniRef50_P94592 Uncharacterized phosphatase ywpJ n=7 Tax=Bacillaceae
           RepID=YWPJ_BACSU
          Length = 285

 Score =  263 bits (675), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 73/289 (25%), Positives = 128/289 (44%), Gaps = 32/289 (11%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLL+  H +S   +  L+     GI  V +TGR H DV  I + L IK+++
Sbjct: 2   KLIAIDLDGTLLNSKHQVSLENENALRQAQRDGIEVVVSTGRAHFDVMSIFEPLGIKTWV 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE--- 119
           I++NGA +HD +G L     +D+  A D+   + ++ +    V+     +  ++  E   
Sbjct: 62  ISANGAVIHDPEGRLYHHETIDKKRAYDILSWL-ESENYYYEVFTGSAIYTPQNGRELLD 120

Query: 120 ----------------------EMRFFKEAVFQYALYEPGLLEPEGV--SKVFFTCDSHE 155
                                 E+++ +        ++      E +    +       E
Sbjct: 121 VELDRFRSANPEADLSVLKQAAEVQYSQSGFAYINSFQELFEADEPIDFYNILGFSFFKE 180

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           +L    +       + + +  S     E+ +   SKG AL+ +AK+L   L++  A GD 
Sbjct: 181 KLEAGWKRYE--HAEDLTLVSSAEHNFELSSRKASKGQALKRLAKQLNIPLEETAAVGDS 238

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +ND  ML  AGKG  MG+A + +K +     V  TN +  V H ++ L 
Sbjct: 239 LNDKSMLEAAGKGVAMGNAREDIKSIADA--VTLTNDEHGVAHMMKHLL 285


>UniRef50_B0P090 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P090_9CLOT
          Length = 298

 Score =  263 bits (675), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 67/276 (24%), Positives = 124/276 (44%), Gaps = 17/276 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLD TLL  +  +S + +E LK    RG+  V ATGR    + +   ++    Y
Sbjct: 26  IKLVAMDLDNTLLDSEKQISKHTEEVLKEAIRRGVYIVPATGRIFKAIPEFLRDIPGVRY 85

Query: 62  MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            +  NGA V+D  +  +I+ ++L ++    LF ++        ++Y++ + +M R   + 
Sbjct: 86  AVCCNGATVYDQKENKIIYTNHLPKETVFSLFDILEKY-HCTRDIYQNGQGYMERCYFDH 144

Query: 121 MRFFKEAVFQYALYEPGLLEPEG-----------VSKVFFTCDSHEQLLPLEQAINARWG 169
           +  +  +     L     L  +            + K+    D  E+     Q +  +  
Sbjct: 145 LAEYGVSDHVLKLVRDTRLPLDDLRKYIEERPLGIEKINVFFDDMEERETARQELIEK-- 202

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           +  +VS S    +E+   G  KG  L  +A+++G S+ + +A GD  ND  M+   G G 
Sbjct: 203 NIASVSSSLGNNIEINQIGCDKGDGLLHLAEQIGLSMDEVMACGDAGNDTMMIKAVGTGV 262

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +M +    LK++     V  TN +D V + + KL  
Sbjct: 263 VMENGQPDLKEIAD--FVTKTNNEDGVAYAIEKLVF 296


>UniRef50_C6PXU7 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PXU7_9CLOT
          Length = 272

 Score =  263 bits (674), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 71/274 (25%), Positives = 133/274 (48%), Gaps = 15/274 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+    D+DGTLL+    +S   +E LK + + G+  + A+GR  + +      LE+   
Sbjct: 4   YKWCVCDMDGTLLNSQSIISEENEEALKKIKSEGMEVIIASGRTDLMINCFVKQLELTGP 63

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I+SNG  + D+  G ++++  +++  A ++     +N +I   +Y  D+ + N+  P  
Sbjct: 64  VISSNGGLIRDMKTGKILYSKLIEKSAAEEILSYCCEN-NIDFLIYSFDKVYSNKGNPLG 122

Query: 121 MRFFKEAVFQYALYEP---------GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
           +++ K +   +   +            ++   V K+   C  HE+++ LE+  +     +
Sbjct: 123 IKYEKLSKDPFQKMKVPVEYLENAVRSIKNINVIKILLVCSEHERVIELEKHFSK--NKQ 180

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           +    S    L++MA  VSKG+AL+ +A+ +   LK+ IAFGD  ND EML   G    M
Sbjct: 181 ITAVSSAKGLLDIMAPNVSKGNALKFLAENMDMDLKNVIAFGDNYNDMEMLKCVGMPIAM 240

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +A Q LK       V  +N +  + + + K  L
Sbjct: 241 ENAVQDLKLQAKH--VTKSNNESGIAYAINKFVL 272


>UniRef50_C5RPZ1 Cof-like hydrolase n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RPZ1_CLOCL
          Length = 277

 Score =  263 bits (674), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 68/275 (24%), Positives = 116/275 (42%), Gaps = 17/275 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++V  D+DGTLLS  H + P   E +K  T  G+    ATGR         + L IK+ 
Sbjct: 3   IKLVCIDMDGTLLSNHHEVHPKNLEAIKKATDLGVKIAIATGRIFASAKIYCELLGIKTP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I++NG  +      ++  HN+  +    +  V+     +   +Y  D    N + PE  
Sbjct: 63  IISANGGYIR-YGDTVMAEHNMGYENCKKIVEVLEKFKSVYY-LYTADSMITNANIPETH 120

Query: 122 RFFKEA-----------VFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            +                    + +      + + K     +  E++  + Q IN   G 
Sbjct: 121 PYRSMNDQLSDKDKLKFYHYDDISDAVENHGDKIIKCIVMEEDFEEIQKIRQDINKIQG- 179

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + V  S    +E+MA GV+KG   EA+AK  G+S  + +  GD  ND  M++ AG G  
Sbjct: 180 -LEVVSSYTNNIEMMAAGVTKGKGAEALAKYYGFSRDEVMCIGDSENDLSMVTYAGFGVA 238

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           MG+ ++ +K       +  TN +  V   + K  +
Sbjct: 239 MGNGNEAVKKAAK--YITDTNVEGGVGKAIEKFVI 271


>UniRef50_C6CYC3 Cof-like hydrolase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CYC3_PAESJ
          Length = 265

 Score =  263 bits (674), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 69/263 (26%), Positives = 111/263 (42%), Gaps = 6/263 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y ++A D+DGTLL+ DH L+   +E ++    RG + V  TGR    V  + + L +   
Sbjct: 5   YDLIALDVDGTLLTDDHQLTSKTREAVREAADRGASIVLCTGRAPFSVFPVLEELGLTGT 64

Query: 62  MITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT NG    D D   +I  + +              N  +  +V    E  +    PE 
Sbjct: 65  IITHNGGATIDSDTRRIIHEYGIAPQQLEPFVDYCRKN-QVHYDVNTAFEMMVESLTPEV 123

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
              + +     ++   G   PEG+ K      S E +  +++    +W   ++   S   
Sbjct: 124 SDMYSKFHASPSVLGQGASLPEGLVKFTVFG-SKEVMDRVQEEW-EKWPPSLHTIRSGDF 181

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            ++V     SKG AL   A   G      +A G+  ND  ML  AG G  MG++   +KD
Sbjct: 182 FIDVHHPEASKGRALRQFASSRGIDRSRILAIGNYYNDISMLEFAGCGIAMGNSPDGVKD 241

Query: 241 LHPELEVIGTNADDAVPHYLRKL 263
                 V  +NA+D V + LR+ 
Sbjct: 242 AAD--VVGRSNAEDGVAYALREF 262


>UniRef50_A8UBX5 Putative uncharacterized protein n=1 Tax=Carnobacterium sp. AT7
           RepID=A8UBX5_9LACT
          Length = 269

 Score =  263 bits (674), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 70/273 (25%), Positives = 129/273 (47%), Gaps = 11/273 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A D+DGTLL+  H ++   K+ +K  +  GI  V  TGR    V    + L++  
Sbjct: 1   MIKLIAIDMDGTLLNEHHLVTDKVKKAIKEASNAGIKIVLCTGRPVHAVYDYFEELDLPK 60

Query: 59  --KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
             + Y+I+ NG  V    +  ++++H LD         ++     +    + +  ++   
Sbjct: 61  DEEDYVISLNGTVVQKTTNWEIVYSHQLDHSQLKKAEQLIEPFE-MNFTYFDEKAYYYTG 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPE--GVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
            + E ++F  + +   A++ P    PE   + K  +  +  E L  L  ++ A   +   
Sbjct: 120 KKTEMLQFDADLLGMDAVHLPLEELPEELTIFKAMYVAEETE-LDHLAASMPAFISENFY 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              S    LE++  G +KG AL  +A KLG+S+ + +A GDG ND +M+ +AG    MG+
Sbjct: 179 PIRSLSYVLELLPQGANKGEALTGLATKLGFSMDEVMAIGDGENDLDMMKVAGTSVAMGN 238

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A   +K       V  +N +D V H + +  L+
Sbjct: 239 AVDSIKLTAK--YVSKSNQEDGVAHAIYEWALN 269


>UniRef50_C7N949 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7N949_LEPBD
          Length = 274

 Score =  263 bits (674), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 72/276 (26%), Positives = 110/276 (39%), Gaps = 14/276 (5%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A D+DGTLL+    +    KE +      GI  V  TGR    +      L +  
Sbjct: 1   MIKLIAIDMDGTLLNEKKHIEKAQKEAIHEAIEAGIKIVLCTGRPLYGILPFYKELGLQE 60

Query: 59  ---KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN 114
              + Y+I +NG  VH   D  LI    +  D    L+          T V  D+  + N
Sbjct: 61  LDQEGYVILNNGCSVHKTKDWELIECAEITPDDMEHLYKFSEKYDINFTLV--DETHYFN 118

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPEGVSK----VFFTCDSHEQLLPLEQAINARWGD 170
             R        +A F ++      LE     K            E++   +        +
Sbjct: 119 IGRKPTKELIMDAQFVFSDITDITLEEAKSGKYKIVKVMFLGDPEEMKKFQTEYEDMIKE 178

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           R     S     EV+  G +KG  L+ +A+KLG   ++ +A GDG ND EML  A  G  
Sbjct: 179 RYEGVLSQSYVYEVLPKGYNKGTGLKNLAEKLGIKQEEVMAIGDGNNDVEMLEYANYGVA 238

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           MG+A +  ++         TN +D V   +RK  L+
Sbjct: 239 MGNASKLARNAAK--YTTDTNENDGVAKAIRKYALN 272


>UniRef50_C9KQH1 HAD phosphatase family protein n=2 Tax=Clostridia
           RepID=C9KQH1_9FIRM
          Length = 274

 Score =  263 bits (674), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 70/277 (25%), Positives = 123/277 (44%), Gaps = 14/277 (5%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A DLDGTL + +  ++   +E L  +   G+  V A+GR    + +    L++K 
Sbjct: 1   MYKMIALDLDGTLNNDEKKITEKTREALLSVQQHGVTVVLASGRQAPGLAREAQALDLKD 60

Query: 61  Y---MITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           Y   +++ NG R+ D   G ++F   +DR  A      +   P++   V   +  F    
Sbjct: 61  YHGLLLSYNGGRIQDATTGEVLFDQAIDRATALRFLRHLEAYPELSPIVDDGESIFTTDA 120

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEG-----VSKVFFTCDSHEQLLPLEQAINARWGDR 171
           R  +++               + +          K+  T   +E L+P  + I   + D 
Sbjct: 121 RRHKVQDESRNNNLKVEIVANIADAVEARGFAPVKIL-TAAPNEILVPRLEDIRRGFEDE 179

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           ++   S     E    GVSK  +L  V ++ G +  + +AFGD  ND  ML  AG G  M
Sbjct: 180 LSFVQSAPWFYEATVKGVSKSTSLAIVCERFGIARAEVMAFGDAQNDMSMLDFAGHGVAM 239

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYL-RKL-YLS 266
           G+A   LK++    E+  +N +D +   L R   +L+
Sbjct: 240 GNACPELKEMAD--EITLSNNEDGIAASLTRHFDFLN 274


>UniRef50_D0BK11 Cof family protein n=2 Tax=Granulicatella RepID=D0BK11_9LACT
          Length = 278

 Score =  263 bits (674), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 64/270 (23%), Positives = 111/270 (41%), Gaps = 9/270 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL---E 57
           M +V+A DLDGTLL+ D  ++P  K+ ++L   +G+  V  TGR  + +  + + L    
Sbjct: 1   MIKVIALDLDGTLLTDDKKVTPENKKAIQLAKEQGVKIVLCTGRPLMSIYHLLEELELLG 60

Query: 58  IKSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVND--NPDIITNVYRDDEWFMN 114
              + I  NG  +       ++F     RD     +        P ++ ++ R  E    
Sbjct: 61  DDDFSINYNGGIIQKTKSQEILFKQGHSRDDMQYCYEEAYKVGLPLVMIDLERAYETTYP 120

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
             RP         + ++    P   E   V      C     L    + +   + ++ N 
Sbjct: 121 EGRPSIYPGLPHPI-EFITKNPSEFEESHVFYKAVLCIEESLLDKGIRQLPEAFFEKFNC 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LEV+   VSKG  L  +A+ LG ++++  A GD  ND  ML+  G    MG+ 
Sbjct: 180 MKSRTFLLEVVPKEVSKGTGLTHLAEILGITVEEIAACGDEENDLSMLTTVGFPVAMGNG 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
              +K++     +  TN +  V H +  + 
Sbjct: 240 SPEVKEVAK--FITKTNEESGVAHAIYHIL 267


>UniRef50_B9CKY2 Phosphatase YidA n=1 Tax=Atopobium rimae ATCC 49626
           RepID=B9CKY2_9ACTN
          Length = 273

 Score =  263 bits (673), Expect = 5e-69,   Method: Composition-based stats.
 Identities = 68/272 (25%), Positives = 108/272 (39%), Gaps = 9/272 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
           Y+++ASDLD TLL  +H L    +E +     +G+ FV A+GR++  +      L +   
Sbjct: 4   YKLIASDLDETLLDSEHCLPKNVREAVLAARKKGVKFVPASGRNYQSIQVTLRELGLYDQ 63

Query: 59  -KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y I+ N   +  + D ++I    +  + A+++        D+  +VY   + +    
Sbjct: 64  PDEYTISFNSGIITENKDNHIISMEGISHEFANEILQRALTLGDLCVHVYTAHKIWAWNV 123

Query: 117 RPEEMRFFKEAVFQYALYEPG--LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
              E  +  +        EP    L  E + K          L  L         D ++V
Sbjct: 124 PEIERFYTSKLQKMDETTEPNLAFLAGEKIIKCLVMNTDAAYLHRLAAEWQDITED-IDV 182

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           SFS    LE    G++KG  L  +   L    KD IA GD  ND  M+  AG G  M + 
Sbjct: 183 SFSANRYLEFNKKGINKGTGLVRLGHILNIPTKDIIAIGDNYNDLPMIKTAGLGVFMANT 242

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
            + LK     +     N    V   + K  LS
Sbjct: 243 PEELKSQADYVT-TLDNNAGGVAEVIEKFVLS 273


>UniRef50_C3WDI3 Hydrolase n=2 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WDI3_FUSMR
          Length = 267

 Score =  262 bits (672), Expect = 6e-69,   Method: Composition-based stats.
 Identities = 84/264 (31%), Positives = 145/264 (54%), Gaps = 2/264 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V SDLDGTLL+  H +S Y   T++ L  +GI FV ATGRH+ D     + + +  Y
Sbjct: 3   YKIVVSDLDGTLLNSQHRISDYTVSTIRKLEKKGIKFVIATGRHYEDAKYFFNQIGVAKY 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I+ NG+ +H  + N I   ++DR +   L   +        ++Y+  +W+ +R   + +
Sbjct: 63  LISGNGSFIHSENWNEIGRESIDRKLIKTLLE-LEVEEGTSRSIYKGKDWYTDRIVQDYI 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR-VNVSFSTLT 180
            F KE+ +   +      +     K+FF   + + +  LE+ +     D+ +N++ S  T
Sbjct: 122 DFHKESKYSPQISNLDKFKNVEAEKIFFINPNRKVIEKLEKKMKNLELDKYLNIATSQPT 181

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLE+M+   +KG AL+ + K      K+ I+FG  +ND EML  +G G IMG+  +RLK+
Sbjct: 182 CLEIMSKKANKGEALKTLLKYENIDFKEIISFGAALNDKEMLENSGMGIIMGNGDKRLKE 241

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
           +  E +VIG++ +DA   +L  L+
Sbjct: 242 ILKECKVIGSSDEDAAAKFLENLF 265


>UniRef50_A6BG65 Putative uncharacterized protein n=5 Tax=Clostridiales
           RepID=A6BG65_9FIRM
          Length = 272

 Score =  262 bits (672), Expect = 7e-69,   Method: Composition-based stats.
 Identities = 58/271 (21%), Positives = 106/271 (39%), Gaps = 12/271 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           YQ++  DLDGTL +    ++    E L  +   G   V A+GR    V  + + L ++ Y
Sbjct: 3   YQILVLDLDGTLTNSKKEITQPTLEALIEIQEAGKKVVLASGRPTQGVMPLAEQLHLEDY 62

Query: 62  ---MITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNP--DIITNVYRDDEWFMNR 115
              +++ NG R+ D      I+   L  D    ++  V       I    Y  +      
Sbjct: 63  GSYILSFNGGRITDCRTKQAIYNKILPADCIQGVYKTVRKYASQGIDVLTYTPEHILSGI 122

Query: 116 HRPEEMRFFKEAVFQYALY---EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
              +             +          P+  +K   T      L  + + ++ ++   +
Sbjct: 123 KSNQYTELESRINQMPVIDASENFLDCVPDDPNKFLVTG-DPAVLDQIRKELSKQFHSYL 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           +V  S    +EVM  G+ K H+L  +   +G + +  I  GDG ND  M+  AG G  M 
Sbjct: 182 SVYCSDPFFVEVMPAGIDKAHSLLKLLTSIGLTTEQMICCGDGYNDLTMIETAGLGVAMA 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           +A   +++      +  +N +D V H + + 
Sbjct: 242 NAQPAVRETAD--YITKSNDEDGVLHVINEF 270


>UniRef50_A0Q2R8 Cof-like hydrolase n=1 Tax=Clostridium novyi NT RepID=A0Q2R8_CLONN
          Length = 269

 Score =  262 bits (670), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 65/269 (24%), Positives = 115/269 (42%), Gaps = 8/269 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY+++A D+DGTLL+ D  +S     T+     RGI     TGR +  +      + +  
Sbjct: 1   MYKLIAIDMDGTLLNSDKKVSKENIATINEAMKRGIRVAICTGRPYSGIEPYAKEIGLCK 60

Query: 59  -KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I+ NG+ V +  D   I A  L+ +  + +   + D    +  V   D    N  
Sbjct: 61  DDEYIISQNGSYVSNGNDTKTISAKYLNVEETNKILSYLEDKEIGVVLVTDKDYLAYNCE 120

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSK--VFFTCDSHEQLLPLEQAINARWGDRVNV 174
             EEM+   + VF+         +     K       D+  ++  + + ++    +   V
Sbjct: 121 INEEMKRDADLVFKTIKMFDKSKDSIENLKLVKIMIMDNSHKIDNIIENMDKNIINSCYV 180

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    +E+MA  V KG+ L  +A+ L    KD +  GD +ND  M  +AG G  M +A
Sbjct: 181 VRSMPYLIEIMAKNVDKGYGLSKLAEHLNIDHKDIMVIGDELNDIGMFKVAGLGVAMANA 240

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKL 263
           +  +K L     +  +N ++ V + +   
Sbjct: 241 NIEIKRLAD--FITLSNDENGVSYAIDYF 267


>UniRef50_B1L8F5 Cof-like hydrolase n=6 Tax=Thermotogaceae RepID=B1L8F5_THESQ
          Length = 268

 Score =  262 bits (670), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 72/266 (27%), Positives = 124/266 (46%), Gaps = 8/266 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDN-LEIK 59
           MY+V   DLDGTLL+    +S   ++ ++ L +R  + VFA+GR  V    +        
Sbjct: 1   MYRVFVFDLDGTLLNDSLEISEKDRKVIERL-SRNCHVVFASGRMLVSTLNVEKKYFGRT 59

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
              I  NGA V+  +  +I    +  ++A D+   V    ++    Y DD  +  +   E
Sbjct: 60  FPTIAYNGAMVYIPEEGVILNEKIPPEVAKDIVEYVKQF-NVHWQAYIDDVLYSEKDNEE 118

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGV--SKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
              + K +  +Y +    L     V  +K+    D+ E+L  L++ +  ++ + V V  S
Sbjct: 119 IRGYAKHSSVEYRVEPKLLELVSKVGTTKILLI-DTPEKLDELKKILLEKFNNVVKVFKS 177

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
             T LE++   V KG AL  + +++G+  ++ + FGD  ND  M   AG    MG+A  +
Sbjct: 178 FPTYLEIVPENVDKGKALRFLRERMGWKKEEIVVFGDNENDLFMFEEAGLRVAMGNAIDK 237

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKL 263
           +K+      V  TN D  V H L ++
Sbjct: 238 VKEAAD--VVTLTNNDSGVSHVLERI 261


>UniRef50_A9KKJ5 Cof-like hydrolase n=3 Tax=Clostridiales RepID=A9KKJ5_CLOPH
          Length = 275

 Score =  262 bits (670), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 71/270 (26%), Positives = 123/270 (45%), Gaps = 8/270 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            +V+A DLDGTL + +  ++   KETL+     G+  V A+GR  V +  +   LE+   
Sbjct: 3   IKVLALDLDGTLTNSEKKITLNTKETLQRAMEDGVTVVLASGRPLVGIKPLAKELELSKY 62

Query: 60  -SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH- 116
             Y++  NG ++ D   G  ++   L+ +  + ++ V      +    Y  ++       
Sbjct: 63  SGYILAYNGGQIIDCHTGKEVYQKVLNVERIASIYEVAKQF-GVAMLTYDGEDIITEDDT 121

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
            P  +R       +    E  +               HE+LLP+   +  ++GD +++ F
Sbjct: 122 DPYVLRECFINKVKVRKIEDIVSHVTYPVPKCLVVGEHEKLLPVRDYLKDKYGDELSIYF 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE+M  GV K  +LE +  +L  S ++ +A GDG+ND  ML  AG G  MG+A  
Sbjct: 182 SEPFFLEIMPLGVEKSASLELLLNRLQLSREELMACGDGLNDITMLQYAGLGVAMGNACN 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             K++     +  TN +D V   + +  LS
Sbjct: 242 EAKEVSK--YITATNDEDGVAKAVNRFILS 269


>UniRef50_A9H329 Cof-like hydrolase n=1 Tax=Gluconacetobacter diazotrophicus PAl 5
           RepID=A9H329_GLUDA
          Length = 292

 Score =  261 bits (669), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 66/265 (24%), Positives = 107/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++V SD+DGTL++PD  L+P   +T + L A GI     + R    +      L I + 
Sbjct: 18  IRLVISDIDGTLVTPDKRLTPAVLDTARALRAAGIALCLVSSRPPRGMEMFLGPLGIDTP 77

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
               NG  V   DG +I   +LD D A    G++  +  +   ++   +W +       +
Sbjct: 78  RAGLNGGLVTQPDGTIISRLSLDPDAAQQAVGMLQSH-GVDAWLFVGHDWLITDPDGAYV 136

Query: 122 RFFKEAVFQYALYEPGLL-EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
              +  V    +  P        V K+      +  L  +E  I  R   R +V  S+  
Sbjct: 137 ERERRTVQTDPVVLPDFAGHYNDVGKIMGASSDYPLLARMEADIGTRLAGRASVHRSSDY 196

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L++     +KG+A   +A+ +   + D    GD  ND  ML  AG    MG+A   +K 
Sbjct: 197 YLDITHPQANKGYAALELARLMDIDIHDVACIGDMNNDIPMLDEAGVSIAMGNAPDGVKA 256

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 V  TN  D   H + +  L
Sbjct: 257 HA--HFVTDTNEQDGWAHAMERYVL 279


>UniRef50_B9DT57 Putative haloacid dehalogenase-like hydrolase n=2 Tax=Streptococcus
           RepID=B9DT57_STRU0
          Length = 266

 Score =  261 bits (669), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 76/269 (28%), Positives = 126/269 (46%), Gaps = 7/269 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  ++ SD+DGTLL+  H +S   K  +K    +GI FV  + R    +  I  +   + 
Sbjct: 1   MVSIIFSDIDGTLLNDQHEVSSRTKTAIKECLRKGILFVPVSARMPKAIKPITCSFLPEI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVND-NPDIITNVYRDDEWFMNRHRPE 119
            +I+ NGA V D  G  I +  +  D+A  +   V +   DI+ N+Y  +EW       +
Sbjct: 61  PIISYNGAFVQDKTGYPISSSPMPFDVALSICSTVEEQFNDIVWNIYSGEEWISQDRDNK 120

Query: 120 EMRFFKE--AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
            ++  +E  +V    +    +     + K+    +    +   E+     + D ++++ S
Sbjct: 121 WVKREEEIVSVTSIQMALETISHSLTIHKLLLMGE-PGSIAKAERLFKENYSD-LSIAQS 178

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LE+MA G++KG A+  +A   G  L D IAFGD  ND +ML   GKG +MG+A   
Sbjct: 179 YPYYLEIMASGITKGKAVTELATSYGVELGDTIAFGDNFNDLDMLQTVGKGYVMGNAPTD 238

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           LK L    +V   N  D +   L +  L+
Sbjct: 239 LKSL--IGDVTTDNNHDGIAEVLERTILT 265


>UniRef50_C6JKA3 HAD-superfamily hydrolase subfamily IIB n=3 Tax=Fusobacterium
           RepID=C6JKA3_FUSVA
          Length = 264

 Score =  261 bits (669), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 70/266 (26%), Positives = 127/266 (47%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + VA DLDGTLL+ D  +S   ++ LK L  +G+     TGR +       + L +   
Sbjct: 3   IKAVALDLDGTLLTTDKKISDINRDVLKELEQQGVKIFIVTGRTYHAAKPYAEYLNLGGV 62

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH-RPE 119
           +I+ NGA+V +  +  ++F   L  +   ++  +      +  N+Y+D++W++    R E
Sbjct: 63  VISYNGAKVVEYRNDRVVFELPLQEEYVKEIIRIARKM-GVALNLYQDNKWYVEDSSRKE 121

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            + + +E        +    +   ++K  F     + L  + + +    G++V  + S  
Sbjct: 122 VLEYARERNLIPIEKDFYSFDNYEMTKTVFMGT-PDILDKVNREVEKVLGNKVYKAKSMD 180

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
           T  EV+   V+KG  LE   K  G S ++C AFGD +ND EML++   G  MG+A   +K
Sbjct: 181 TLYEVLNREVNKGLVLERTLKTYGISPEECAAFGDAVNDIEMLTVVKYGVAMGNAPHEVK 240

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
                  +  TN ++ V  +L+K + 
Sbjct: 241 SRVN--YITDTNDNNGVAKFLKKFFF 264


>UniRef50_Q030F1 Predicted hydrolase of the HAD superfamily n=34 Tax=Lactobacillales
           RepID=Q030F1_LACLS
          Length = 281

 Score =  261 bits (669), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 56/267 (20%), Positives = 109/267 (40%), Gaps = 5/267 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIR---DNLEI 58
            +++A DLDGTLL+    +S   +  +     +G++ V  TGR  + +       + L+ 
Sbjct: 17  IKLIALDLDGTLLNSSKEISKENRLAIDAARQKGVHVVLTTGRPLIAIQPFLKTLEMLDF 76

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
           + + IT NG  V    G ++   +   D   ++  +      I  +V  +++ +M +   
Sbjct: 77  EDFSITFNGGLVQRNTGQILSKKSFTHDEILEIKELTTK-LGIPCDVLSEEKVYMTKSDV 135

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
                    +  +   +   +  + V     +C   E L      I   + +   +  + 
Sbjct: 136 VSQYDTLNKLLTFIKVDFDQVTLDVVYNKIVSCTDKELLDAQLSKIPESYFEEFEIFKTQ 195

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              LE M  G++K + L  +  +L    ++ +A GD  ND  M+S AG G  M +A   +
Sbjct: 196 AKLLEFMPKGINKAYGLTQLTNQLNLGAENVMAMGDEANDLSMISWAGYGVAMANAVPAV 255

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K+    +    TN   AV H + +  L
Sbjct: 256 KEEARIIS-DLTNDQHAVAHMIERYVL 281


>UniRef50_C7RFK7 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7RFK7_ANAPD
          Length = 265

 Score =  261 bits (668), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 73/267 (27%), Positives = 114/267 (42%), Gaps = 7/267 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY- 61
           +++  D+DGTL++    ++   +E L      G   V  TGR       + + LE   Y 
Sbjct: 2   KLIGVDVDGTLVNSKRVITERTREALISAMKAGHKVVIVTGRPTAGARNLAEALEFDKYG 61

Query: 62  --MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             + + NG  + D   G ++  H +D DIA ++  +  D P + T V   D  F  +  P
Sbjct: 62  GLISSFNGGAITDFATGKVLANHEMDHDIAVEMIKLAKDLP-LETMVPYMDTVFSPKIGP 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
                 +    +    E      +            + +      I  R+GD      S 
Sbjct: 121 YTEGEARTLRMEAKEVEDLDQTIDFPVNKILFAADPDLIDEPTSKIKERFGDLTEQVKSA 180

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
               EVM  G+SKG++L  +AK      KD IAFGD MND  M+  AG G  MG+A  ++
Sbjct: 181 RFYYEVMPMGLSKGNSLLEIAKIFNIDQKDIIAFGDEMNDETMIEAAGVGVAMGNAVSKI 240

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K++     V  TN +D + +YL K  L
Sbjct: 241 KEIAD--YVTLTNDEDGIAYYLDKFIL 265


>UniRef50_B8DIC3 Hydrolase, Cof family n=18 Tax=Listeria RepID=B8DIC3_LISMH
          Length = 288

 Score =  261 bits (668), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 75/289 (25%), Positives = 127/289 (43%), Gaps = 30/289 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +V+ASD+DGTLL+ D  ++    E ++   A+GI+FV  TGR + D   + +   + +
Sbjct: 1   MIKVIASDMDGTLLNSDIEIAQENVEAIEKARAKGIHFVLCTGRMYDDAMGLINKANLYA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRD-----------D 109
             I  NGA + D  G +I  H +DR++A + +  + +   + T  + D            
Sbjct: 61  PAICMNGAEIRDEHGKIILQHPIDRNLARNTYNTLTE-LGMYTEFFTDMGPITTDKARGK 119

Query: 110 EWFMNRH-------------RPEEMRFFKEAVFQYALYEPGLLEPE-GVSKVFFTCDSHE 155
           E+ +  H                E RF  + V +    E  L   +  + K        +
Sbjct: 120 EFMIEMHKRIHPDVSAETIMDKVEERFESKDVHEIPDVERILGNKDLTILKFISFSSDKD 179

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
            L   +Q +       ++V+ S    +E+      KG +L+   +KLG +L +  A GD 
Sbjct: 180 ILAKAKQKLEK--DSELSVTSSFSDNIEITHREAQKGISLQYYVEKLGVTLDETFAIGDN 237

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           MND  ML MAG    MG+  + +KDL     V  +N +  V   + K+ 
Sbjct: 238 MNDISMLKMAGYSVAMGNGEEEVKDLAEH--VTLSNDEHGVAAAIYKML 284


>UniRef50_A5Z5X7 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
           ATCC 27560 RepID=A5Z5X7_9FIRM
          Length = 269

 Score =  260 bits (667), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 61/267 (22%), Positives = 112/267 (41%), Gaps = 7/267 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK--- 59
           +V+  DLDGTL + D  ++P   + LK +   G     A+GR    V Q+   LE+    
Sbjct: 4   KVLFLDLDGTLTNDDKKVTPKTLKALKQIMEEGHIVALASGRPTPGVAQVAKTLELDKYG 63

Query: 60  SYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y+++ NG +V +     +I+ + L ++   +L      N  I    Y DD   +     
Sbjct: 64  GYVLSFNGGKVINWKTKEVIYENALSKEYIPELVDYATGNK-IGLITYDDDSIVVGTPID 122

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           E +             +  +   +            E     E+ ++ ++  R+++  S 
Sbjct: 123 EYIELESFINKLPLKEKNLVEYVDYNPNKCLLTAPGEIAAEHEKILSKKFEGRISIYRSE 182

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              +E +  G+ K H++E +   LG   ++ IA GDG ND  M+  A  G  M +A   +
Sbjct: 183 PFFIEALPMGIDKAHSIEVLINHLGIPKENTIACGDGFNDLTMIKYAHVGVAMANATDVV 242

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K+      +  +N +D + H + K  L
Sbjct: 243 KENAD--YITKSNNEDGIAHVIEKFIL 267


>UniRef50_Q1WS49 Hydrolase, HAD superfamily n=2 Tax=Lactobacillus salivarius
           RepID=Q1WS49_LACS1
          Length = 277

 Score =  260 bits (667), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 67/276 (24%), Positives = 121/276 (43%), Gaps = 12/276 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           MY++VA D+D TLL+ D  +SP     LK     G+  V  TGR ++ V +    L I  
Sbjct: 1   MYKLVAIDMDETLLNDDAEISPKNVSVLKKAIKDGVKVVLNTGRSYLSVQENLKTLGIYQ 60

Query: 59  --KSYMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGV-VNDNPDIITNVYRDDEWFMN 114
               Y+++ NG  +  + D  ++    L  DI   LF + +   P+   +VY  DE +M 
Sbjct: 61  TKDQYVVSFNGGAIVENKDLKVVHVEGLTFDIVKQLFDISLRYYPESCIHVYTLDELYMW 120

Query: 115 RHRPEEMRFFKEAVFQYALYEP---GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
               +E  + +    ++   +      LE   ++K+    +  ++ L   +      GD+
Sbjct: 121 NVNQDEKDYLQPRGVEWTELQEPNIDFLEDTPITKIIINVNDMDKRLAFNEIARKEIGDK 180

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
              ++S+   +E       KG  +  +A+ LG   ++ IA GD  ND  M+  AG G  +
Sbjct: 181 FKTTYSSGRYIEFNNISTDKGTGMLKLAEMLGIKPEETIAIGDNSNDLPMIEAAGVGVAV 240

Query: 232 GSAHQRLKDLHPELEVIG-TNADDAVPHYLRKLYLS 266
            +A++++        +    N  DAV   + K   +
Sbjct: 241 RNANEQVLSKAD--YICKRDNNHDAVAEAVDKFVYN 274


>UniRef50_C2EN69 HAD family hydrolase n=7 Tax=Firmicutes RepID=C2EN69_9LACO
          Length = 272

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 74/274 (27%), Positives = 129/274 (47%), Gaps = 12/274 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A DLD TLL     +    K+ ++  T  G+ FV ATGR +  + Q  D + +K 
Sbjct: 1   MYKLIACDLDETLLDDHAHVCQRNKDAIEAATKLGVKFVPATGRGYNAIAQTLDEINLKD 60

Query: 61  ----YMITSNGARVHDLDGNLIFA-HNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I+ NG  + +  GN I     L  D A++L+ +     ++  +VY  D  ++  
Sbjct: 61  KANEYVISFNGGCITENKGNRIMKFQGLSWDKANELYQLGLKY-NVCIHVYTKDMLYVYH 119

Query: 116 HRPEEMRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
              EE+ + K   A       +   L+ + ++KV +       L  +   I++   D ++
Sbjct: 120 ADEEELNYIKLRHAYQIIDDQDLDFLKGQEIAKVLYGNPDVPYLEKIANEISSSTKD-LD 178

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           VS+S+   LE    GV+KG  L  +A KLG  L++ +A GD  ND  M+  AG G  + +
Sbjct: 179 VSYSSNRYLEFNHQGVNKGAGLIWLANKLGIKLEETMALGDNFNDLSMIKAAGLGVGVAN 238

Query: 234 AHQRLKDLHPELEVI-GTNADDAVPHYLRKLYLS 266
            + ++K+      V      +  V   + K  L+
Sbjct: 239 VNPQMKNECD--FVTNADYKEGGVGEAIEKFVLN 270


>UniRef50_Q0STC6 HAD hydrolase, IIB family n=9 Tax=Clostridium perfringens
           RepID=Q0STC6_CLOPS
          Length = 277

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 64/278 (23%), Positives = 121/278 (43%), Gaps = 20/278 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGTLL+    +S   +  LK    +G++ +  TGR+  +     + L +   
Sbjct: 3   YKMICIDMDGTLLNSKKVVSEENRIALKKAYEKGVHIIICTGRNPKNAIYFSEFLGVNCA 62

Query: 62  MITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF-------- 112
           +I +NGA V D D ++ I    L+ +   D+  +  +   +I + +  D  +        
Sbjct: 63  VIANNGAWVIDEDKDIVISKDVLNENQCMDIMNICKEYK-VIPSFHSKDSVYWPSRFRKY 121

Query: 113 -----MNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
                +N+  PE+ R     V +   +     +   + K      +  +L  + + +  +
Sbjct: 122 LCDIILNKKIPEKYRVKNIYVKEKEEWREVF-KSNNIGKCIIIELNTSKLKKIRENLIKK 180

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
                 ++ S    LEV   GVSKG A+EA+A++     ++ I  GD  ND  M++ AG 
Sbjct: 181 --GNYEITQSGRYALEVNNKGVSKGRAVEALAEEYKIKREEIICIGDNENDLSMINYAGL 238

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G  MG+A   LK       +  +N  + V   + +  L
Sbjct: 239 GVAMGNAIDSLKKKAD--YITESNDKNGVAKVIYEFVL 274


>UniRef50_A8ST52 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=A8ST52_9FIRM
          Length = 277

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 59/268 (22%), Positives = 110/268 (41%), Gaps = 8/268 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK--- 59
           +++A D+DGTL +    ++P   + +  +  +G     A+GR    + +I D +++    
Sbjct: 8   KLLALDIDGTLTNTQKDITPETLKKIIEVQEKGHVVAIASGRPLPGIRKIADIIQLDRFG 67

Query: 60  SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            Y++  NG R+ +   G +++   LD +I  D++             Y  D         
Sbjct: 68  GYVLAFNGGRIVNYKTGEVVYQAALDNEIVRDIYDYCLK-VGCGMVTYDGDRVITGTDID 126

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEG-VSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
             M F         +      E               ++   +E+ + +R+GD+V +  S
Sbjct: 127 GYMTFEASINHMELMRIDDFKEYIDFPLNKCLLTAEPDKAEKIEEELVSRFGDKVTIFRS 186

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               +E+M   V K  +LE +   L   ++D IA GDG ND  M+  AG G  M +A   
Sbjct: 187 EPYFVEIMPQNVHKATSLEKLLGVLNMDVRDLIACGDGYNDLTMIEYAGVGVAMANAQDI 246

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +K       +  +N +D +   + K  L
Sbjct: 247 VKKHAD--YITLSNDEDGLVPVVDKFIL 272


>UniRef50_UPI0001C430CB Cof-like hydrolase n=1 Tax=Bacillus pseudofirmus OF4
           RepID=UPI0001C430CB
          Length = 277

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 57/253 (22%), Positives = 111/253 (43%), Gaps = 7/253 (2%)

Query: 18  HTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY---MITSNGARVHD-L 73
           HT+S   KE L      GI  V A+GR    +  + + L++  Y   +++ NGA++ +  
Sbjct: 24  HTISSRTKEALMQAQKNGIKVVLASGRPTYGMVPVANELKLADYGSFILSFNGAKIINSK 83

Query: 74  DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFQYAL 133
               +++  L      +L+  V+   ++  + Y +++     +    M   +        
Sbjct: 84  TNEEMYSSTLSPKQLHELY-HVSQRENVGIHTYMENDIVTEANNEYTMIEGEITGMPVIE 142

Query: 134 YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGH 193
            E  +   +            ++L+ +E+ +   +  +++V  S    LE    GV+KG 
Sbjct: 143 VERFVDAVDEPCVKALMVGHPDRLVEVEKKLQEEFRGQLSVMRSKPYFLEFTEDGVTKGA 202

Query: 194 ALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNAD 253
           +L ++  KLG   ++ IA GD  ND  M+  AG G  MG+A   +K++     V  TN +
Sbjct: 203 SLHSLITKLGIKQEEVIAMGDSYNDQTMIEFAGLGVAMGNAPDDIKEIAD--YVTDTNMN 260

Query: 254 DAVPHYLRKLYLS 266
           D V   + +  L+
Sbjct: 261 DGVAKVVEEFVLN 273


>UniRef50_Q1JAD8 Hydrolase n=30 Tax=Streptococcus RepID=Q1JAD8_STRPB
          Length = 293

 Score =  260 bits (666), Expect = 3e-68,   Method: Composition-based stats.
 Identities = 68/272 (25%), Positives = 113/272 (41%), Gaps = 8/272 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M Q++A DLDGTLL+ D  +       ++     G+  V  TGR         D L +  
Sbjct: 20  MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGRPQSGTRPYFDQLGLTQ 79

Query: 59  KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRH 116
           + ++I +NG   +   D  L  +  L       L  +    PDI   +  ++++ +    
Sbjct: 80  EEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFPDIYLTLTEENDYLVLEEE 139

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVF--FTCDSHEQLLPLEQAINARWGDRVNV 174
            P+ ++   + VF            +    +F          L   E+A+  +     +V
Sbjct: 140 VPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEKAALDAFERAVRNQLSQSFHV 199

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
             S    LE++  GVSK  AL+ + + LG +    +A GD  ND EML+ AG G  M +A
Sbjct: 200 VGSQDNILEILPQGVSKASALKELVEDLGLTADQVMAIGDAPNDIEMLTYAGLGVAMENA 259

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              +K L  +  V  TN    V   +R+  L+
Sbjct: 260 SAAIKPLADK--VTLTNDMAGVAQAIRQFALA 289


>UniRef50_C6CZV3 Cof-like hydrolase n=3 Tax=Bacillales RepID=C6CZV3_PAESJ
          Length = 250

 Score =  260 bits (666), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 59/264 (22%), Positives = 102/264 (38%), Gaps = 19/264 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++VA D+DGTLL+    +S    E ++     GI   F+TGR         + L++++ 
Sbjct: 4   YKLVALDMDGTLLNDQSEISEENAEWIQRALDAGITVSFSTGRGFRGALPFAEQLKLETP 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           MIT+NG+ +      L     L       L  +   +       Y     +         
Sbjct: 64  MITANGSEIWQRPHVLHKRTLLSPVYVKQLHELALKHEGTWFWAYSTTGIY--------- 114

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
                   +  +      E     K  +  +       +   I     D + ++ S+   
Sbjct: 115 ------NLEKWIDPSTTYEDHHWLKFGYYTEDDVIRNRILAEITEW--DALEITNSSTQN 166

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+   G++K  AL  +   LG  +   +A GD +ND   +  AG G  MG+A Q +KD 
Sbjct: 167 LELNPKGITKASALRELCTMLGIEMSQVVAAGDSLNDIAAIREAGLGVAMGNAQQAVKDA 226

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                V  TN ++ V   +++  L
Sbjct: 227 ADA--VTLTNNENGVAEIIKQYVL 248


>UniRef50_C7NEL2 Cof-like hydrolase n=3 Tax=Leptotrichia RepID=C7NEL2_LEPBD
          Length = 263

 Score =  260 bits (665), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 67/261 (25%), Positives = 122/261 (46%), Gaps = 4/261 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + +  DLDGT+L+ +H +S    + L+ L  +G+    ATGR  +      + LEIK+ 
Sbjct: 4   IKAIFMDLDGTVLTSEHKVSENLIKKLRELEEKGVKTFIATGRTFISSKPFVEMLEIKNP 63

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I  NG RV +  +  +IF   ++     +L  V  +   I  N+Y DD+ ++     E 
Sbjct: 64  VINYNGGRVTNPLNNEVIFEKPVEAQDVKELIKVSREK-GIHLNLYMDDKLYIENETDEG 122

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            ++ +     Y +        +  +K  F  ++   +L   +         +N  FS   
Sbjct: 123 KKYSESVEIPYYVKNFDEFIGKTSTKALFITENS--ILLELKKELEEKLPHINFVFSKPH 180

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE +   V+KG A++ + KK   S ++ +AFGD  ND EML     G +MG+A + LK 
Sbjct: 181 YLECLNKEVNKGLAIKELLKKYDISPEETMAFGDQWNDLEMLKFVKYGYLMGNATEELKQ 240

Query: 241 LHPELEVIGTNADDAVPHYLR 261
              + ++  +N +D +   ++
Sbjct: 241 EFSKDKITLSNDEDGIYEVIK 261


>UniRef50_D2LWT0 Cof-like hydrolase n=1 Tax=Bacillus cellulosilyticus DSM 2522
           RepID=D2LWT0_BACS4
          Length = 247

 Score =  260 bits (665), Expect = 5e-68,   Method: Composition-based stats.
 Identities = 60/264 (22%), Positives = 118/264 (44%), Gaps = 23/264 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A D+DGTLL+ DH++S   +  +      G+  V +TGR  + +    ++L + SY
Sbjct: 4   IKLIALDMDGTLLNSDHSISDANRLAIMEAEQNGMTVVISTGRSILTLKPYIESLNLSSY 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           ++T NG+ + D  G +     L  D+   ++  +    D+       ++ +         
Sbjct: 64  IVTVNGSLIWDNKGEVFDQSELAPDLIKMMWD-LKKKYDLHFWAVTPEKVW--------- 113

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
                       +    +E     K  +  +  +    + + ++    DR+ ++ S    
Sbjct: 114 ---------RDEFPEDEIEAHEWLKFCYHIEDDKTRKTVFEFLSK--DDRLEITNSNPVN 162

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE+ A G++K  AL  + ++LG ++ + +A GD +ND  M+  AG G  MG+A   +KD 
Sbjct: 163 LEINAAGINKASALRKICEELGITMDNVLAMGDSLNDIAMIKEAGVGVAMGNAQPVVKDA 222

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                V   N +D V   ++K  L
Sbjct: 223 ADW--VTTKNNEDGVALGIKKFAL 244


>UniRef50_A6T5I9 HMP-PP phosphatase n=18 Tax=Bacteria RepID=COF_KLEP7
          Length = 272

 Score =  259 bits (664), Expect = 6e-68,   Method: Composition-based stats.
 Identities = 95/264 (35%), Positives = 145/264 (54%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++ A D+DGTLL PDH L       LK L  R I   FATGRH +++  +     + +
Sbjct: 1   MAKLAAFDMDGTLLMPDHRLGEKTLSALKRLRERDITLTFATGRHVLEMHHVIGEFSLDA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +++T NG R+H L+G  ++  +L  + A  +      +     +V+ D  WF  + RPE 
Sbjct: 61  FLVTGNGTRIHSLEGEELYRQDLAPEAAEAVL-HGKWDTQASMHVFNDGGWFTGQARPEL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++    + F Y L +   +  + V+K+ F C  H+ L  L   +N   GDR  + FS + 
Sbjct: 120 LQAHVFSGFHYQLCDLKRMSAQHVTKICF-CGDHDDLRRLRIQLNETLGDRAFLCFSAMD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV+  G +KG AL  +++ LG++L++C+AFGD MND EML   G+G IMG+A  +LK 
Sbjct: 179 CLEVLPVGCNKGAALAVLSQHLGFTLQECMAFGDAMNDREMLGSVGRGFIMGNAMPQLKA 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
             P L VIG   + AV H+L    
Sbjct: 239 ELPHLPVIGDCRNQAVSHFLTHWL 262


>UniRef50_B9DRH4 Haloacid dehalogenase-like hydrolase n=11 Tax=Streptococcus
           RepID=B9DRH4_STRU0
          Length = 275

 Score =  259 bits (664), Expect = 6e-68,   Method: Composition-based stats.
 Identities = 62/271 (22%), Positives = 106/271 (39%), Gaps = 8/271 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++A DLDGTL + + T+S   K  ++  +A+G+  V  TGR    +G + + L +   
Sbjct: 4   IKLLALDLDGTLFNAEKTISDANKLAIQKASAKGVKIVITTGRPLAAIGNVLEELGLTSD 63

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             Y IT NG  V    G ++   +L  +  + +   + +N  + T++  + + +    + 
Sbjct: 64  DDYCITFNGGLVQRCTGQILDKSSLSYEEVATVHQHL-ENLALPTDILSEGKVYSIPSKD 122

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEG---VSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                +  A       E   LE      V     T    + L      +     +     
Sbjct: 123 GRHSQYHLANPLLQFIEINSLEDLPKNIVYNKIVTVTDADFLDQQLSLLPPSTFEAFESF 182

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S     EVM  GV K   L+ +   L    K+ +A GD  ND  ML  +G G  M +A 
Sbjct: 183 KSRDIIFEVMPKGVHKAFGLQLLCSHLKIEAKEVMAMGDEANDFTMLEWSGLGVAMANAV 242

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
              K +   +    TN    V   + K  L+
Sbjct: 243 AEAKQIADAVT-SQTNDQSGVAEAIEKYILN 272


>UniRef50_B2IW20 Cof-like hydrolase n=18 Tax=Cyanobacteria RepID=B2IW20_NOSP7
          Length = 289

 Score =  259 bits (663), Expect = 7e-68,   Method: Composition-based stats.
 Identities = 55/271 (20%), Positives = 113/271 (41%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGT+    +T+S   K+ +    A+GI    ATGR +    +   ++     
Sbjct: 21  IKLLVLDIDGTIAGHSNTISAGVKQAIVAAQAQGIPVAIATGRMYRSALRFHQDIGSTLP 80

Query: 62  MITSNGARVHDLDGNLIFAH-NLDRDIASDLFGVVND---NPDIITNVYRDDEWFMNRHR 117
           ++   GA + D +   I  H  + R++A  L            +  + Y +D+ ++    
Sbjct: 81  LMAYQGAWIQDPNTQQIHRHWAISREMAHQLLDYFEQPELRSLLSVHFYINDQLYVRELT 140

Query: 118 PEEMRFFKEA-VFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARW-GDRVNVS 175
            E   + + + +    + +         +K+    D  + +  L   +  ++    + ++
Sbjct: 141 RETQIYAERSAIIPIPVGDLRQTLTNEPTKILALSDDTDLIDRLLGNLRRQYTPAELYLT 200

Query: 176 FSTLTCLEVMAGGVSKGHALEAVA-KKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
            S  T  E     V+KG A+  +A + LG  + + +A GD  ND EML   G G  MG+A
Sbjct: 201 TSVATFFEATNASVNKGTAVRYLAEELLGLEIANVMAIGDNFNDVEMLESVGLGVAMGNA 260

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            + ++ +     V  +  +D     + K  L
Sbjct: 261 PEGVQAIAQW--VAPSVEEDGAAVAIEKFLL 289


>UniRef50_C2KAT0 Possible sugar-phosphatase n=1 Tax=Chryseobacterium gleum ATCC
           35910 RepID=C2KAT0_9FLAO
          Length = 266

 Score =  259 bits (663), Expect = 7e-68,   Method: Composition-based stats.
 Identities = 64/266 (24%), Positives = 107/266 (40%), Gaps = 4/266 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++ +D+DGT L+  H +SP   E  K L  R I FV A+GR    +      +E +  
Sbjct: 4   IKLIVTDMDGTFLNSSHEMSPEFSEVYKELKKRNIVFVPASGRQMPGITHYFGEIESEIG 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            I  NG  V       +FA  L+     D+   V + P     +      +      + +
Sbjct: 64  FIAENGGYVI-YKDQELFADTLEYKYIVDIIKAVREIPGAKAVLSAKKMAYYETEDQQFV 122

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            FF +   +    +    + +  +              L  A+       + +  S    
Sbjct: 123 DFFSKYYTENMKKDDLTEKIDDTAFKIAVYHPEGSEKHLYPALKKFEEFGLEIVVSGAHW 182

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           L+VM   ++KG+AL+ + K LG S ++ +AFGD MND EML  A     M +AH  +K +
Sbjct: 183 LDVMNKDINKGNALKILQKSLGISPENTMAFGDYMNDIEMLKNAKYSYAMQNAHPNVKQV 242

Query: 242 HPELEVIGTNADDAVPHYLRKLY-LS 266
                   TN    V   ++    L+
Sbjct: 243 AN--FEACTNDSFGVLKTIKDYLHLN 266


>UniRef50_Q7MFQ8 Predicted hydrolase n=24 Tax=Vibrionales RepID=Q7MFQ8_VIBVY
          Length = 267

 Score =  259 bits (663), Expect = 8e-68,   Method: Composition-based stats.
 Identities = 61/265 (23%), Positives = 108/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            + +A+D+DGTLL P   L+P      + L  +GI F  A+GR +  + +    +  +  
Sbjct: 6   IKFIAADMDGTLLDPSGKLAPEFFHIYQTLEDKGIIFAAASGRQYYSLRETFAPINDRMM 65

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            I  NG  V    G  +++  L      D+  +          +      ++    PE +
Sbjct: 66  FIAENGTLVMH-QGKELYSCGLASTDIKDIIQLTRTIDGAHIVLCGKKSAYVETKHPEAI 124

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
               +   +   Y P LL+ +        C        L  + + R+     V  S    
Sbjct: 125 EEISKYYHRCQ-YVPDLLDVDEAFIKVAICHFEGSQEKLHTSFSERFDATHQVVVSAKIW 183

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           L+VM    SKG A+  + + LG++ +  ++FGD  ND EML  +     M +AH  +K L
Sbjct: 184 LDVMNAEASKGAAIRHLQQTLGFTRQQTMSFGDYFNDVEMLKQSYHSYAMANAHPEVKAL 243

Query: 242 HPELEVIGTNADDAVPHYLRKLYLS 266
                +  +N +  V   +++  LS
Sbjct: 244 A--RFIAPSNEESGVLQVIQQQVLS 266


>UniRef50_Q8KA73 Uncharacterized protein BUsg_029 n=5 Tax=Buchnera aphidicola
           RepID=Y029_BUCAP
          Length = 274

 Score =  259 bits (663), Expect = 8e-68,   Method: Composition-based stats.
 Identities = 121/265 (45%), Positives = 183/265 (69%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+++A+DLDGTLLSP++ ++ Y ++ +K L  +G  FVFA+GRH++D+ +IRD L IK 
Sbjct: 1   MYRIIAADLDGTLLSPENKITKYTEKIIKFLIEKGFYFVFASGRHYIDIMKIRDTLNIKV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +MITSNGA+V+DL+  LIF ++LD +IA  L  +   + DIIT VYR+++W++N ++ + 
Sbjct: 61  FMITSNGAQVYDLNNVLIFENHLDEEIALKLCKMKYLDADIITQVYRNNQWYINNNKIDN 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                 +  +Y  + P +   + VSKVFFT  + ++L  L++ I +  G+RVNV FS   
Sbjct: 121 NFCPTLSSLRYKYFCPDVFNFKKVSKVFFTSHNLKKLHTLQKDIISFLGNRVNVHFSVPG 180

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV++G VSKG+ L+ ++  LG SLK+CI FGDGMND +MLS++GK CIM +A   LK 
Sbjct: 181 CLEVVSGEVSKGYGLKLISNILGISLKECITFGDGMNDQDMLSISGKACIMENADSSLKK 240

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
             P  EVIG+N +D V  +L K ++
Sbjct: 241 NLPYAEVIGSNKNDGVAVFLNKNFI 265


>UniRef50_Q4D2M6 Haloacid dehalogenase-like hydrolase, putative n=2 Tax=Trypanosoma
           cruzi RepID=Q4D2M6_TRYCR
          Length = 311

 Score =  259 bits (663), Expect = 8e-68,   Method: Composition-based stats.
 Identities = 111/269 (41%), Positives = 158/269 (58%), Gaps = 9/269 (3%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS-YM 62
            V +DLDGTLL+  H++S Y  ETL+LL  +GI  +FATGR + DV    +   +   Y+
Sbjct: 40  AVVTDLDGTLLNEHHSISEYTAETLRLLKNKGIAIIFATGRAYFDVFHTVEKCGLHGGYL 99

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPD-------IITNVYRDDEWFMNR 115
           ITSNGARV D     I  H++D ++ S+L  +  D+ +         TN YR +EW  NR
Sbjct: 100 ITSNGARVFDPQRRAIVTHDVDPEVVSELINIKLDDENQDAEDSSFATNFYRHEEWLTNR 159

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                +  +  + F+Y   +      +GV  VFF  + HE LL +E+ + +R+  +V  S
Sbjct: 160 GSERMLVAYAGSGFRYKEMDLNTCPHDGVHSVFFLGE-HEVLLRVEKVLESRFQGKVEHS 218

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    L+ +  GV+KG+A+  VA+ LG S K+ IAFGDGMND +ML MAGKGC+MG+A 
Sbjct: 219 MSHPLVLDTVRWGVNKGNAMCEVAQLLGISAKEIIAFGDGMNDLKMLQMAGKGCVMGNAQ 278

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            RLK+  P LEVIG N +D V   LR ++
Sbjct: 279 SRLKEALPHLEVIGCNTEDGVARKLRAVF 307


>UniRef50_UPI000196AEDD hypothetical protein CATMIT_00603 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196AEDD
          Length = 275

 Score =  258 bits (662), Expect = 9e-68,   Method: Composition-based stats.
 Identities = 67/268 (25%), Positives = 118/268 (44%), Gaps = 11/268 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++A DLDGTL + ++ ++   +ETL      G   V A+GR    +      LE++  
Sbjct: 3   YKLIALDLDGTLKNSENKITDATRETLIKAQQLGATVVLASGRPTPGLRHEAAALELEKY 62

Query: 60  -SYMITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NGA+V D      +F   L  + A   +     + ++    Y DD  +     
Sbjct: 63  EGYLLSFNGAKVMDAKTRQTMFEQRLTVEQAKKAYDEAKKH-NLAIMTYYDDAVYTEDVD 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEP--EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
            + +                      + ++KV  T D       LE   +A  G  +++ 
Sbjct: 122 DQYVNIEGHINDIEIKKAESFKSILRDPINKVLCTGDPEHVASVLEDYKSAFLG--LSIY 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    +EVMA  + K  +L+ + K L  + ++ IAFGDG ND  ++  AG G  M +A 
Sbjct: 180 RSAPFFIEVMAPNIDKAASLDKLVKMLHLTKEEVIAFGDGFNDLSLIEYAGCGVAMANAV 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKL 263
             +K+      V  +N +D + + L+KL
Sbjct: 240 DEVKERAD--VVTLSNDEDGIAYMLKKL 265


>UniRef50_B0BRY2 Predicted hydrolases of the HAD superfamily n=7 Tax=Pasteurellaceae
           RepID=B0BRY2_ACTPJ
          Length = 263

 Score =  258 bits (662), Expect = 9e-68,   Method: Composition-based stats.
 Identities = 62/268 (23%), Positives = 118/268 (44%), Gaps = 10/268 (3%)

Query: 1   MYQ----VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL 56
           M +     V SD+DGTLL+  H ++P  ++ ++ +  +GI F+  + R  + +      L
Sbjct: 1   MKKPLYLAVFSDIDGTLLNTAHQITPLTRQAIQSVMQKGIPFIPVSARPPLAITPYTQQL 60

Query: 57  EIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           +    +I  +GA + D D + +++  +++   + L  ++     +  N Y   +WF N  
Sbjct: 61  QSYYPIICYSGALILDQDLSQLYSVVIEQADLNRLDLLLEKYQHLSINHYAGIDWFTNDL 120

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             E     +E+                V K+    +  EQ+  LE+ +  +    + +  
Sbjct: 121 ENEWT--VQESEITGLQAVEKTKNLTDVHKILVMGE-AEQIQSLEKLLKQQLP-HLAIHR 176

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE+M    +K +A+  +   L  +    IAFGD  ND +ML  AG    MG+A +
Sbjct: 177 SKNEYLEIMNKQATKSNAIRFMETILNVNQDQVIAFGDNFNDLDMLQYAGLSVAMGNAPE 236

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +K       V  +N DD +   L +++
Sbjct: 237 EIKAAAKR--VTLSNNDDGIAVVLNEIF 262


>UniRef50_B5CTA9 Putative uncharacterized protein n=4 Tax=Clostridiales
           RepID=B5CTA9_9FIRM
          Length = 279

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 62/268 (23%), Positives = 113/268 (42%), Gaps = 11/268 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
           YQV+  DLDGTL +    ++   ++ L  +   G   V A+GR    V  +   L ++  
Sbjct: 11  YQVIVLDLDGTLTNSKKEITEPTRQALIDIQKNGKTVVLASGRPINGVAPLAKQLRLQDF 70

Query: 61  --YMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNP--DIITNVYRDDEWFMNR 115
             YM++ NGARV    DG +I+   +  ++   +  +V       +    Y D    ++ 
Sbjct: 71  GGYMLSFNGARVTRCSDGKIIYNKQIPPEMIRPICDIVRSYAEQGVDLITYTDTTI-ISA 129

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEP--EGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
             P +    +  + +  +Y+P       +            + L  L + +  ++   +N
Sbjct: 130 IAPNQYTRIESGINRMEIYQPDDFVSYIDFPINKLLVPGPADVLQELMKLLKEKYHGLLN 189

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           +  S    LE+M   + K H+L+ +   +G +    I  GDG ND  M+  AG G  M +
Sbjct: 190 IYLSEPYFLEIMPQNIDKAHSLQKLLNSIGLTADSMICCGDGFNDLSMIEYAGLGVAMEN 249

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLR 261
           A   +KD      +  +N +D V H + 
Sbjct: 250 AQPIIKDSAD--FITRSNDEDGVLHVVN 275


>UniRef50_C5D2V8 Cof-like hydrolase n=3 Tax=Geobacillus RepID=C5D2V8_GEOSW
          Length = 281

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 65/282 (23%), Positives = 111/282 (39%), Gaps = 25/282 (8%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A D+DGTLL+ +  +S   KE +     +G      TGR + D      +  +   ++
Sbjct: 2   LIALDMDGTLLNSNGQVSRRNKEAIVTAQKQGHIVAIVTGRAYKDARAPLRDAGLVCPIM 61

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRF 123
           + NGA +   DG ++    LD++        V   PD+   +Y  D  ++  H    +  
Sbjct: 62  SLNGAVMTLEDGTVLGDVPLDKEKLIPALEWVRAQPDLYCEIYTGDAVYVGLHNRAHLEA 121

Query: 124 FKEAVFQYALYEPGLLEP----------EGV-----------SKVFFTCDSHEQLLPLEQ 162
             E     A     ++E           + +            KV       E+L     
Sbjct: 122 MAEKASDIAPELKRIVEKQFQQARVTYVDDIRAIWEERQTVFYKVLIFSLDQERLQEAAA 181

Query: 163 AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
              A  G  + V+ S    +E+     +KG AL  +A   G  +KD + FGD  ND  M 
Sbjct: 182 QFAAISG--ITVTSSHPNNIEINHEQATKGEALVKLAAHYGIDMKDTVVFGDSHNDLSMF 239

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ++AG    M +A   LK++     V  ++ +D V   L +L 
Sbjct: 240 AVAGYRVAMENAAPGLKEVSDM--VTASHEEDGVAVVLEELI 279


>UniRef50_C4V675 HAD superfamily hydrolase n=1 Tax=Selenomonas flueggei ATCC 43531
           RepID=C4V675_9FIRM
          Length = 278

 Score =  258 bits (661), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 59/265 (22%), Positives = 97/265 (36%), Gaps = 5/265 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++  SDLDGT+L     +S      ++     G+    ATGR       + + L +   +
Sbjct: 4   KLFVSDLDGTMLPSGDIVSSENIAAVQCAVRAGVTVTIATGRMFEAALPVAEALGVDVPI 63

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I  NGA +    G +   H +D  +A D+              Y            E   
Sbjct: 64  IAYNGALIKSPSGRIYEEHAIDPMLARDIITFAQAR-GWYIQSYSGGVLRYAIACEESRF 122

Query: 123 FFKEAVFQYALYEPG--LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           +                L    G  K+    +         Q +   +G  + V+ S   
Sbjct: 123 YENSQKITGKAVGRNGMLAYVTGNCKLLLVTEGRAVSEARAQMLMDAFGAHIGVTRSADR 182

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            +E++  GVSK  AL A+A KLG +  + +A GD  ND  ML  AGK   MG+A   +K+
Sbjct: 183 LVEIVVKGVSKASALTALAAKLGITADETMAIGDAYNDLPMLKAAGKSVAMGNAFPEVKE 242

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                    +  ++ +   +    L
Sbjct: 243 EAD--YETLSCTENGLAAAIYTYVL 265


>UniRef50_B2GFE5 Hydrolase n=12 Tax=Lactobacillus RepID=B2GFE5_LACF3
          Length = 273

 Score =  258 bits (660), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 65/274 (23%), Positives = 112/274 (40%), Gaps = 12/274 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++A D+DGTL++    ++   KETL+  TA+GI  V  TGR    V +  D L I   
Sbjct: 3   IKLIAIDIDGTLINDQLEITEKTKETLQKATAQGIKVVLCTGRPMTGVHKYLDQLGINNL 62

Query: 59  -KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y+I+ NGA      G +I    L  +   DL  V     D+       D  ++    
Sbjct: 63  ADQYVISFNGALAQTTSGQVISQFTLPFEKLVDLSAVALK-ADVHLLAETADAMYVLNQD 121

Query: 118 PEEMRFFKEAVFQYAL-----YEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
                 ++ ++    +      +   ++ + V       D    +      + A      
Sbjct: 122 ISSYAVYESSLVSLPITYKSIDQLNTIKNDLVISKLMITDEPAAIDGFSAKLTAPIKRAF 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           N+  S    LE +    SKG AL ++ ++LG +  + +A G+  ND  M++ AG G  M 
Sbjct: 182 NIVRSEPYYLEFVNPSASKGAALASLGQELGVARTEMMAIGNAQNDESMITYAGIGVAMS 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           ++      L    E++  N  D V   + K  L+
Sbjct: 242 NSIPSTIQLAD--ELVADNNHDGVAEAVEKFALA 273


>UniRef50_A5KNX9 Putative uncharacterized protein n=8 Tax=Clostridiales
           RepID=A5KNX9_9FIRM
          Length = 305

 Score =  258 bits (660), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 68/276 (24%), Positives = 113/276 (40%), Gaps = 17/276 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  DLDGTLL+    L+   +E L      GI  + ATGR  + V +        +Y
Sbjct: 28  IKMIGLDLDGTLLTDKKELTVRTREVLAKAIRSGIVVLVATGRPWMGVPEELREFPGMNY 87

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN------ 114
            +TSNGAR+ D   GN+I  H L    A     +     D +  VY D + +        
Sbjct: 88  ALTSNGARIIDTRTGNVIEEHLLSVKSAKKALEICRKY-DTLQEVYFDGQGYAPAEKMEF 146

Query: 115 ----RHRPEEMRFFKEAVFQYA-LYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWG 169
                  P    + ++       ++E    E  G+ K         +     + +     
Sbjct: 147 VERYHKNPNMWEYMRKTRIPVDDIFELVDRENRGLDKTQALFADMSERKRAWEELARH-- 204

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           + + +  S    +EV A GV+KG  L  +  +LG   ++ +AFGDG ND  ML   G G 
Sbjct: 205 EDLELVGSLRYNIEVNAAGVNKGTGLVNLGSRLGIKREEIMAFGDGDNDTVMLKEVGFGV 264

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            M +   ++K+      +  +N +D V   + +  L
Sbjct: 265 AMANGEPQVKEAAD--YITLSNEEDGVAQAIERFVL 298


>UniRef50_C1P6V3 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36D1
           RepID=C1P6V3_BACCO
          Length = 285

 Score =  257 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 71/288 (24%), Positives = 116/288 (40%), Gaps = 31/288 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D DGTLLS D T+S      ++ +  +G   V  +GR   D   I     +   +
Sbjct: 2   KLIAIDFDGTLLSDDGTISEENAGAIREVQEQGNIVVACSGRSLHDTRHILKKAGLDCPV 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NRHRPEEM 121
           IT NGA ++D D   I    +   +  DL   +         +Y +   ++  + R    
Sbjct: 62  ITGNGAVIYDSD-QCILKLVMPDKVLDDLLPELEAQ-GYYYELYTNQGVYLLEKGRKRLE 119

Query: 122 RFFKEA------------------------VFQYALYEPGLLEPEGVSKVFFTCDSHEQL 157
                                         +  +  Y    L    V K+F      E+L
Sbjct: 120 SEMHSLHEKDETFSLEWAAGQIELQMRQYGIHYFHHYAELDLPHLEVYKIFVLSFHPERL 179

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
             L   ++ R    ++++ S  T LE+    VSKGHAL+ +A+ L   L++ +A GD  N
Sbjct: 180 KQLRSWLSGR--QDLSMTTSGRTKLEIAHAEVSKGHALQFMARHLNIPLENTVAIGDNFN 237

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           D  M  +AG    MG+A +++K       V  T+  + V H LR   L
Sbjct: 238 DLSMFEVAGISIAMGNAEEQVK--ARSTYVTKTHNKNGVAHALRTYIL 283


>UniRef50_Q1WSZ0 Hydrolase, HAD superfamily n=9 Tax=Lactobacillales
           RepID=Q1WSZ0_LACS1
          Length = 291

 Score =  257 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 62/290 (21%), Positives = 116/290 (40%), Gaps = 31/290 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M Q++ASD+DGTLL+    +S    + +K     G++F+ ++GR + ++  + +  +  S
Sbjct: 1   MIQIIASDMDGTLLNDKMVISKRNADAIKEAQKNGVHFIVSSGRGYNEIKPLIEAADFNS 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            MIT NGA V D +G ++ +  L +  A  +  ++     +   V      + +      
Sbjct: 61  PMITLNGAEVLDENGKVLSSSPLPKITAKKIIRLLRK-KGLYAEVITSKGIYSDNKAKRI 119

Query: 121 MRFFK-------------------------EAVFQYALYEPGLLEPEGVSKVFFT-CDSH 154
             F +                            +     E    +   V K+     +  
Sbjct: 120 ENFAELLTRVSPDTPYKLAVIMASNRLELMNINYTDDYMELIDEKHTKVFKIVAFSSEGK 179

Query: 155 EQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGD 214
           + L P+   I+      + V+ S+ + +E+      KG AL+A A  L   + + +A GD
Sbjct: 180 KVLDPIRDEISQ--NSELVVTSSSESNIEINHVNAQKGIALQAYADYLNIPMDNVMAIGD 237

Query: 215 GMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             ND  ML +AG    M +    +K L     +  TN  D V   + ++ 
Sbjct: 238 NNNDVSMLKVAGMSYAMENGSNEVKMLAKR--IADTNTSDGVGKAIEEVL 285


>UniRef50_C9LXL5 HAD-superfamily hydrolase, family protein IIB n=1 Tax=Selenomonas
           sputigena ATCC 35185 RepID=C9LXL5_9FIRM
          Length = 268

 Score =  257 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 63/266 (23%), Positives = 113/266 (42%), Gaps = 5/266 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++ +D+DGTLL   + +S   +  LK   A+G++   ATGR H+        + +   
Sbjct: 3   IRMIVTDMDGTLLDAKNGISEKNRAALKEAAAKGVHVAIATGRMHLSALPYAKEIGVTVP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +++ NGA V    G  +FA  +  D+  ++   + ++       Y D+  F         
Sbjct: 63  IVSCNGALVKTTAGEELFASPIAPDVVREILDCMKEH-GWYVQPYTDEGLFFCERDCRAC 121

Query: 122 RFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            + K A  +      +  L     V K+    D  E+       I+  +  +V    S  
Sbjct: 122 AYEKLAGIEGKAVGWDGLLALGTRVFKLLSISDRAEETAVRAAEISRMFEGKVRAVRSKE 181

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +++MA GVSK  ++E +A  LG ++ + +A GD  ND EML+ AG G  M +     +
Sbjct: 182 KYVDIMAEGVSKAASIERLAASLGINMSEVLALGDSDNDCEMLAAAGIGVAMATGTPAAR 241

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
           +      +    A D V   +    L
Sbjct: 242 EAAD--FLAENGAADGVARAVHAYVL 265


>UniRef50_C2LPY8 HAD-superfamily hydrolase, subfamily IIB n=5 Tax=Streptococcus
           RepID=C2LPY8_STRSL
          Length = 269

 Score =  257 bits (659), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 70/269 (26%), Positives = 113/269 (42%), Gaps = 7/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
            +++ SD+DGT+L+ +H +     E +  L    I FV A+ R  + +  I   L +  +
Sbjct: 4   IRLIISDIDGTILTSNHQVEEQLIEVMPELEKANIPFVLASARSPLGMQPIAHKLGLHDN 63

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVV-NDNPDIITNVYRDDEWFMNRHRPE 119
            +   NGA V + D   I  H +D+    DL   +  D P +  N+Y   +W  N     
Sbjct: 64  PIACYNGALVLEGD-RTIIQHPVDKAEIQDLLNYLSKDYPSVSVNIYSGKDWITNELDKW 122

Query: 120 EMRFFKEAVFQYALYE--PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
                        + E    + + E         D  E +  L Q + +    +     S
Sbjct: 123 SQLEGSITGESPIIKELQDTVSDSEPPIHKLLLIDEPEVIQDLHQKLLSMDFPQTAFYLS 182

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LEV A  VSK HAL  VAK     L+  +  GD  ND+ ML++AG G  MG+A + 
Sbjct: 183 KDNYLEVTAKHVSKEHALLEVAKYYDLPLEQVMTIGDNFNDSPMLALAGLGIAMGNAPEG 242

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +K+      V  +N +  V   + +  L+
Sbjct: 243 VKETANL--VTASNDEHGVAQAITEHVLN 269


>UniRef50_C0Z8L2 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0Z8L2_BREBN
          Length = 279

 Score =  257 bits (658), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 67/280 (23%), Positives = 121/280 (43%), Gaps = 19/280 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+DGT+L  +HTLS   +  +  L  +G++   ATGR +     +     I + 
Sbjct: 3   YKLLALDVDGTILMSNHTLSKVTERAITQLVQQGVHVTLATGRAYPSAKSLAQQFRISAP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH---- 116
           +++ +GA V D     +++   +  +IA+ +  ++  +  +   +  +     NR     
Sbjct: 63  LVSHDGAYVADPKTDQVLYVQRIPHEIAARITDILVSH-GLDVMLLHEAYAVTNRTWKLT 121

Query: 117 ------RPEEMRFFKEAVFQYALYEPGLL-----EPEGVSKVFFTCDSHEQLLPLEQAIN 165
                     +R   +  +   +    L+     + E  +   F     ++LL   Q + 
Sbjct: 122 DLFPLLNAWTLRQLWKNQYPLKIQASRLIAGYVRKHEVCAPKIFVTGDEKRLLEARQELE 181

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
                 + V+ S    LE++  G+SK   L  V+++L     + +A GD  NDAEML  A
Sbjct: 182 KAELSGIRVTASGANNLEILPVGISKASGLAVVSERLAIQPDEIVAVGDNYNDAEMLQFA 241

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G G  MG+A   LK L     V  TN    V   + K +L
Sbjct: 242 GMGVAMGNAPDDLKQLARH--VTETNDRHGVAEVIEKFFL 279


>UniRef50_B0P1S7 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=B0P1S7_9CLOT
          Length = 270

 Score =  257 bits (658), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 67/268 (25%), Positives = 110/268 (41%), Gaps = 8/268 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLDGTL +    ++      +      GI    A+GR    +   RD L++  +
Sbjct: 3   YKLIAVDLDGTLYNDQLKITSDTLNAMIEAQEMGIRIALASGRPLPGLFHARDLLKLNEH 62

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              ++  NG +V D     +++   +  D+A +L   + D P +   +      ++    
Sbjct: 63  HGMLVAYNGGKVVDTTTNEVLYDKYIQDDLAMELLEHLKDYP-VNPIIDDGKVLYVTDKN 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVS-KVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
              ++          +  P L E          T    ++   + + I   + D+V    
Sbjct: 122 GYRVKEEALNDSMEYVEVPSLTEHLDFHLNKILTAVDPQKTYDVLETIGMPFRDQVTFVR 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           +    +E +  G SK   L  V K LG    + IAFGD  ND EM+  AG G  MG+A  
Sbjct: 182 TAPYYIEAIPVGTSKASGLSNVCKGLGIDPSEVIAFGDAENDLEMIQFAGHGVAMGNACD 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            LKD     EV  TN +D + H L  L 
Sbjct: 242 ALKDAAD--EVTLTNNEDGIAHTLNHLL 267


>UniRef50_Q0TU23 HAD-superfamily hydrolase, subfamily IIB n=7 Tax=Clostridium
           perfringens RepID=Q0TU23_CLOP1
          Length = 274

 Score =  257 bits (658), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 65/276 (23%), Positives = 116/276 (42%), Gaps = 16/276 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGTLL     ++   K  +K    +G      TGR +       D + +K+ 
Sbjct: 3   IKLICIDMDGTLLMDQQNIAEEDKNAIKEAVKKGAIVAITTGRIYDCARMYSDTIGLKTP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I SNGA +  ++   I+ + L +    D F ++    ++ T V  +         PE  
Sbjct: 63  IIASNGAYIGGVNDEEIYNNPLKQSDLED-FNIITKKNNLFTYVTTNWGIVSTVELPENH 121

Query: 122 RFF-------KEAVFQYALYEPGLLEPEG----VSK-VFFTCDSHEQLLPLEQAINARWG 169
            +        K+   +  + +      +     + K V    +  ++L   ++ + A   
Sbjct: 122 VYKVLNKTLPKDKQVRLEVVKDLDEAFKKYKGEILKGVCVEKEFKDKLKEAKEELIACTT 181

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
           D + V  S     E+M  G SKG A++ +AK LG S ++ +  GD  ND  M++ AG G 
Sbjct: 182 D-LEVVSSWDDNFEIMKKGSSKGEAVQMLAKYLGVSQEEVMCIGDSENDLSMITWAGTGV 240

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            MG+A   +K+      V   N    V   +RK  L
Sbjct: 241 AMGNAIDSVKEFAN--YVTSDNKHGGVAEAIRKFVL 274


>UniRef50_P70947 Putative phosphatase yitU n=101 Tax=Firmicutes RepID=YITU_BACSU
          Length = 270

 Score =  257 bits (657), Expect = 4e-67,   Method: Composition-based stats.
 Identities = 58/265 (21%), Positives = 107/265 (40%), Gaps = 7/265 (2%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A DLDGTLL  D T+S     T++ L   G     +TGR +         +E+ + ++
Sbjct: 7   LIALDLDGTLLKDDKTISENTLHTIQRLKDDGHYVCISTGRPYRSSSMYYQQMELTTPIV 66

Query: 64  TSNGARVHDLDGNL--IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
             NGA VH    +    +  +L  D+   L  +              D+ + + H    +
Sbjct: 67  NFNGAFVHHPQDDSWGRYHTSLPLDVVKQLVDISESYNVHNVLAEVIDDVYFHYHDEHLI 126

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
             F        + +      E V+ V       + +  +   ++    + ++        
Sbjct: 127 DAFNMNTTNVTVGDLRENLGEDVTSVLIHAKEED-VPAIRSYLSDVHAEVIDHRRWAAPW 185

Query: 182 --LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +E++  G++K   L+ ++   G   +  IAFGD  ND EML  AG G  MG+    +K
Sbjct: 186 HVIEIIKSGMNKAVGLQKISDYYGVPRERIIAFGDEDNDLEMLEFAGCGVAMGNGIDAVK 245

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
            +        TN +D V  +L++ +
Sbjct: 246 QIANR--TTATNEEDGVARFLKEYF 268


>UniRef50_B0N4M8 Putative uncharacterized protein n=3 Tax=Bacteria
           RepID=B0N4M8_9FIRM
          Length = 272

 Score =  256 bits (656), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 68/266 (25%), Positives = 117/266 (43%), Gaps = 10/266 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+++A DLDGTL S D  + P  K  L+ L  RG+  V A+GR    +    + LE+   
Sbjct: 3   YKLIALDLDGTLKSTDKQILPKTKAILQELAKRGVVIVLASGRPTAGLYAEANELELDKT 62

Query: 60  -SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NGA+V D     +I+    D   A  ++       ++    Y D+        
Sbjct: 63  GGYLLSFNGAKVVDYKTKEIIYQKVYDAKTAHQVYERAKQY-NLAVMTYTDELILTEDET 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEG--VSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
            E +    +       +     +     V+KV  T    E    +     A +GD +++ 
Sbjct: 122 DEYVCIEGDINHMPIKHIDNFKDAVNFSVNKVLLTAK-PEYAETILDEFKAPYGDSLSIY 180

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    +EVMA G+ K  +L+A+ ++LG    + I+FGDG ND  M+  A  G  M +A 
Sbjct: 181 RSAPFFIEVMAQGIDKAASLQALIERLGIKRDEVISFGDGYNDLSMIEFAKFGVAMANAV 240

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLR 261
             +K       +  +N ++ +   L+
Sbjct: 241 DEVKKRA--AYITLSNDEEGIYECLK 264


>UniRef50_C7JF38 Hydrolase n=8 Tax=Acetobacter pasteurianus RepID=C7JF38_ACEP3
          Length = 295

 Score =  256 bits (656), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 58/265 (21%), Positives = 111/265 (41%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++V SD+DGTLL+P+  ++ ++   ++ L   G+     + R    +    D L + + 
Sbjct: 19  IRLVVSDMDGTLLTPEKQVTRHSIAAIQTLKQAGVPVCLVSSRPPGGMEMYFDVLGLHTP 78

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
               NG  + + D  +    +LD +   +   ++  + DI   ++R  EW +       +
Sbjct: 79  YGALNGGTIFNADRTIRSRLSLDPEAVQETLDMLKVH-DIDAWLFRGHEWLVTNATGAYV 137

Query: 122 RFFKEAVFQYALYEPGLLE-PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
               +AV       P   +  + V KV  +   +E L+  E  I      R +V+ S   
Sbjct: 138 EPEAKAVRMTPTAVPSFDDYRQDVGKVTGSSADYEALMRQELEIGQLLEGRASVARSCQC 197

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L++     +KG+AL  +A     S+++    GD  ND  MLS+ G    MG +   + +
Sbjct: 198 FLDITPKDANKGYALRQLASFYNISIEEVACIGDMNNDVPMLSIGGLSIAMGQSKPEVAE 257

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 V   N++D     + +  L
Sbjct: 258 TA--HFVTAPNSEDGWAKAMEQFVL 280


>UniRef50_A4VVF4 Predicted hydrolase of the HAD superfamily n=38 Tax=Streptococcus
           RepID=A4VVF4_STRSY
          Length = 271

 Score =  256 bits (656), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 64/273 (23%), Positives = 115/273 (42%), Gaps = 10/273 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTLL+    L     + +      G   V  TGR    V    + L   +
Sbjct: 1   MIKLIALDMDGTLLNEKKELMQPQIDAIHQAVEAGFKIVLCTGRPLAGVKPFVEQLGFDT 60

Query: 61  ---YMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              ++I +NG   H   D +LI    L       L   + +N D+  +++ ++++F+   
Sbjct: 61  EEEFIIVNNGCSTHSTKDWSLIDWEELSISDIDYLSTFI-ENADVQISLFDEEDYFVLAE 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPE-GVSKVF--FTCDSHEQLLPLEQAINARWGDRVN 173
           +          +         L E + G  + F          +   E   N     R +
Sbjct: 120 KANARVNLDAGLVGMTPQPIDLKEAQSGQYRFFEAMFVGEKVHIDAFENQHNPVLSKRYS 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
              S    LE++  G SK   L+ +A +LG   ++ +A GD  ND EM+  AG G  MG+
Sbjct: 180 TVRSQDYLLEILPNGASKASGLKKLADRLGILPEEIMAMGDANNDLEMIEFAGLGIAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           A++++K +  +  +  TN ++ V   + K  L+
Sbjct: 240 ANEQVKAIAQD--ITDTNENNGVAKAIEKHILN 270


>UniRef50_C1P783 Cof-like hydrolase n=1 Tax=Bacillus coagulans 36D1
           RepID=C1P783_BACCO
          Length = 305

 Score =  256 bits (656), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 69/289 (23%), Positives = 117/289 (40%), Gaps = 29/289 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + +ASD+DGTLL+    +SP   E +KL   +GI+FV  TGR + +   + D + I  
Sbjct: 18  MIECIASDMDGTLLNSRQEVSPANAEAIKLAQKKGIHFVVTTGRSYEEARLVLDPVGIDC 77

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE- 119
            +I  NGA V D  G L+    LD   AS +  V  D   I    + +   +   +    
Sbjct: 78  TVIGLNGAEVRDEKGKLLKTSGLDPLTASQVADVF-DQLGIYYEFFTNKGTYTEDYEENM 136

Query: 120 -----------------------EMRFFKEAVFQYALYEPGLLEPEG-VSKVFFTCDSHE 155
                                  E R  +  V      +    +P     K+    +  +
Sbjct: 137 DMLVNLFHTANPEVPVEEVRNYIEQRGIRRYVHNIRDTKDIFHDPSILFYKILAFNEDEQ 196

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           +L  + + +   + D + V+ S    +E+      KG AL+   +K G S++  +A GD 
Sbjct: 197 RLRQIGKHLEKDFPD-IKVTSSGFRNIEINHVSAQKGIALKEYTEKHGLSMEKTMAIGDN 255

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +ND  ML   G    MG+A   + ++         N +D V   + ++ 
Sbjct: 256 LNDISMLERVGYPFAMGNAENEVLEICRYR--TKRNDEDGVAKAIYRML 302


>UniRef50_Q97ES2 HAD superfamily hydrolase n=1 Tax=Clostridium acetobutylicum
           RepID=Q97ES2_CLOAB
          Length = 280

 Score =  256 bits (656), Expect = 6e-67,   Method: Composition-based stats.
 Identities = 67/278 (24%), Positives = 124/278 (44%), Gaps = 20/278 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V  D+DGTLL+  H +S   KE ++   A+G++ V  TGR + +       + +KS 
Sbjct: 3   YKLVCIDMDGTLLNSKHCVSGETKEVIRKAYAKGVDIVITTGRIYANAAFYSKLIGVKSP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I SNGA +   D N+I+ + L  D  S +F V +        ++  D    +      +
Sbjct: 63  VIASNGAIIRGRDNNIIYKNVLSSDTLSRIFNVCSRLKG-NITLHTHDSIICSSKFAYIV 121

Query: 122 RFFK---------------EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINA 166
            +                 + V  Y+ Y  GL E   + K        +++  + + +  
Sbjct: 122 MWVIFIGSIIKNNENTLKIKYVKNYSAYINGLKESNDIIKCEIIDKDVKKISAIREELKR 181

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
              + + V  S+   +EV +  VSKG+A++++A+  G   ++ I  GD  ND  M+   G
Sbjct: 182 M--NDIEVVSSSRHNIEVTSKNVSKGNAIKSLAEFYGIKREEIITIGDSENDLSMIEYGG 239

Query: 227 KGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            G +M +  +  K L     +  TN ++ V   ++K  
Sbjct: 240 LGVVMENGCESAKKLAD--YITDTNDNNGVAKVIKKFI 275


>UniRef50_C0X6C9 HAD superfamily hydrolase n=22 Tax=Enterococcus faecalis
           RepID=C0X6C9_ENTFA
          Length = 277

 Score =  256 bits (655), Expect = 6e-67,   Method: Composition-based stats.
 Identities = 63/278 (22%), Positives = 116/278 (41%), Gaps = 18/278 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            + +  D+DGTLL+ +  +SP  ++ L     +G++ + A+GR    +  + D LE+   
Sbjct: 3   IKAIVMDIDGTLLTSEKKISPKTRQALVAAQKQGLSLILASGRPTNGMRPLADELEMAHY 62

Query: 59  KSYMITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             ++++ NGA V H      +F   + + ++  +   +    D+I  +  +   ++N   
Sbjct: 63  NGHLLSYNGACVTHHGSQQQLFNQTISKSLSQQILEHLKQF-DVIPMINDETFMYVNDVF 121

Query: 118 PEEMR---------FFKEAVFQYALYE--PGLLEPEGVSKVFFTCDSHEQLLPLEQAINA 166
              +           ++     + L E                       L    +AI A
Sbjct: 122 HHTLHLETGDFNIIEYESRGGNFQLCEWHDLAARLNFPLNKILIAGEPAYLQKYHEAIYA 181

Query: 167 RWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG 226
            + + V  +FS     E  A  + K  +LE +  +LG + ++ IAFGDG ND  ML  AG
Sbjct: 182 PFKETVTAAFSAPFYFEFTAKNIDKARSLEKLTLQLGIAAEEVIAFGDGHNDYTMLEWAG 241

Query: 227 KGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            G  M +A + LK +    EV  +N +D +   L    
Sbjct: 242 TGIAMENAVEELKSIA--TEVTLSNDNDGIAVALANFL 277


>UniRef50_C6JK34 Hydrolase n=2 Tax=Fusobacterium RepID=C6JK34_FUSVA
          Length = 258

 Score =  256 bits (655), Expect = 6e-67,   Method: Composition-based stats.
 Identities = 69/262 (26%), Positives = 129/262 (49%), Gaps = 7/262 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V SDLDGTLL     ++ Y K  +K L   GI F  ATGR      +++ ++ +  Y+
Sbjct: 2   KLVVSDLDGTLLDTKSQITDYTKSIIKKLVNNGIEFAIATGRGPASAIKLKKDIGLDIYL 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I +NGA ++D   N IF   +D+ I+ ++  ++ D   +  N + DD+++    R E  +
Sbjct: 62  ICNNGANIYDKKENSIFEKVIDKKISQNIIKLLRDRK-VAYNGFIDDDFY----RDEYDK 116

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
                   +  +  G +E           +  + +L + + +  ++ + V ++ S   C+
Sbjct: 117 TDYSRRTDFIEHILGDIEECPALHKIIIVEEADIILRINKELREKFSNVVEITISDPECI 176

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +++    SKG+AL+ +A++LG  ++  +AFGDG ND +ML   G    M +A   +K   
Sbjct: 177 DIVPKECSKGNALKIIAQQLGIEMERVMAFGDGENDLDMLKKVGHPVAMENAQDIVKKEI 236

Query: 243 PELEVIGTNADDAVPHYLRKLY 264
                   N ++ V  YL K +
Sbjct: 237 NN--TAPKNIENGVALYLEKFF 256


>UniRef50_C6QV31 Cof-like hydrolase n=1 Tax=Geobacillus sp. Y4.1MC1
           RepID=C6QV31_9BACI
          Length = 296

 Score =  256 bits (655), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 76/286 (26%), Positives = 129/286 (45%), Gaps = 30/286 (10%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A DLDGTLL+  + +S    + +K     GI  V ATGR H DV +I  +  I++++I
Sbjct: 6   LMAIDLDGTLLNKHNEISRENIQAMKEAQKNGIEIVVATGRAHFDVQEIFKHTGIRTWII 65

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM-- 121
            +NGA +H  DG L  +  LD+D A ++   + +  +    V+ D   F  +   E +  
Sbjct: 66  GANGATIHKPDGQLFLSTPLDKDKAIEILQWL-EQEEYYYEVFSDSAIFTPQKGRELLSI 124

Query: 122 -----------------------RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLL 158
                                  ++ +      + Y+  L     +  +       E+L 
Sbjct: 125 EMDRLISANPELDSEELKSAALKQYSQSGFVFISSYKELLKPSINIYNILVFSFDKEKLN 184

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
                      + + +  S     E+     SKG+AL+ +AK+LG  L   IA GD MND
Sbjct: 185 RGWNKFQD--CNDLTLVTSANYNFELEHIEASKGNALKILAKELGIPLSQTIAIGDSMND 242

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             M+S+AGKG  MG+A + +K++    EV  +N +  V + + +L 
Sbjct: 243 YSMISIAGKGIAMGNACEEIKNIAK--EVTLSNDEHGVAYVINRLL 286


>UniRef50_P44771 Uncharacterized protein HI0597 n=32 Tax=Pasteurellaceae
           RepID=Y597_HAEIN
          Length = 272

 Score =  256 bits (655), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 115/261 (44%), Positives = 163/261 (62%), Gaps = 1/261 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLE-IKS 60
           ++ + SDLDGTLL+P+H +     +TL+ L  +G++ + ATGR+H DV  I   +   ++
Sbjct: 5   FRAMVSDLDGTLLTPEHLVGDLTIDTLRALEQKGVDIILATGRNHTDVSSILGKIGAERA 64

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            MITSNGARV DL GNL+++++L  ++  +L+    D   +  N Y+D+ WF N+  P  
Sbjct: 65  VMITSNGARVRDLQGNLLYSNSLPEELVLELYKTPFDTSKVCMNSYQDEGWFTNKDIPAM 124

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            +F KE+ F Y + +       G  KVFF   + E L+ +E  +  ++GD   + +S L 
Sbjct: 125 RQFHKESGFDYNVVDFSKHHGRGTEKVFFIGKTPEDLVEVETYLRDKFGDVTTIVYSALA 184

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM   VSKG AL+ + +   Y LKDCIAFGDGMND EMLS AGKGCIM  A  RLK 
Sbjct: 185 CLEVMNKNVSKGDALKHLLESREYELKDCIAFGDGMNDVEMLSWAGKGCIMKDADIRLKM 244

Query: 241 LHPELEVIGTNADDAVPHYLR 261
             PELEVIG+N +++V  YLR
Sbjct: 245 ACPELEVIGSNKEESVARYLR 265


>UniRef50_Q5WG82 HAD superfamily hydrolase n=1 Tax=Bacillus clausii KSM-K16
           RepID=Q5WG82_BACSK
          Length = 246

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 64/264 (24%), Positives = 117/264 (44%), Gaps = 24/264 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A D+DGTLL+ +  ++ + K  ++     GI  V  TGR          +L++ S+
Sbjct: 4   IKMIALDIDGTLLNDNKEITSWTKNQIRKAQHAGITVVLCTGRPFPHCHTYIQDLQLHSH 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
            IT NG +++ +D +++  H  D    ++L+            +   + ++     PE  
Sbjct: 64  SITCNGGQIYAVDHSVMIEHLFDAATLANLYHFAQGLGMNTWTISTKEAYY--NDLPENC 121

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
             ++                    K   +    E L  + + + +   D V VS  T   
Sbjct: 122 SAYQ------------------WLKFSCSHKDEEVLNKMAEKVQSI--DGVEVSNRTAFT 161

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +EV   GV+K  ALE V +KLG ++K  +A GD +ND +M+  AG G  MG+A + ++ +
Sbjct: 162 VEVNPTGVNKAAALEWVCEKLGITMKHVMAIGDSLNDIKMIQSAGIGIAMGNAQKAVQQV 221

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                +  TN +D V   + K   
Sbjct: 222 ADA--ITDTNNNDGVGKAIEKFIF 243


>UniRef50_C1I4C1 HAD superfamily hydrolase n=1 Tax=Clostridium sp. 7_2_43FAA
           RepID=C1I4C1_9CLOT
          Length = 278

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 123/279 (44%), Gaps = 21/279 (7%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V  D+DGTLL     +S  +K+ +K +  +G+  V  TGR + +       L ++S 
Sbjct: 3   YKMVCIDMDGTLLGKGKEISKESKKIIKEIHEKGVEIVVTTGRIYNNAAYYSHLLGVESP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE- 119
           +I +NGA V + +   +I+   ++ +    L   +     +  + Y  D  + +    E 
Sbjct: 63  VIAANGAIVREKNTNKVIYEKPIETEECIKLVEKLYKMK-MHFHFYTLDSIYCSNKLTEL 121

Query: 120 -------------EMRFFKEAVFQYALYEPGLLEPE-GVSKVFFTCDSHEQLLPLEQAIN 165
                         ++     +     ++    +    ++K        E++L +++ + 
Sbjct: 122 GTKLYMTKQIGYDNLKINYYVINNIEKWKDFFRKNHGKITKCIAFSMKPEKILKVKKQL- 180

Query: 166 ARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMA 225
               + +    S    +E+ + G SKG+A++A+A   G+  ++ +  GD  ND  M+  A
Sbjct: 181 -DTFEGIVYYGSGKRSVEINSKGASKGNAVKALANYYGFKREEIMCIGDNENDLSMIEYA 239

Query: 226 GKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G G  MG+A + +K L     +  TN ++ V   ++K +
Sbjct: 240 GVGVAMGNAIEPVKKLAD--YITDTNIENGVEKAIKKFF 276


>UniRef50_P44447 Uncharacterized protein HI0003 n=16 Tax=Haemophilus influenzae
           RepID=Y003_HAEIN
          Length = 262

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 63/264 (23%), Positives = 117/264 (44%), Gaps = 5/264 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V SD +GTLL+  HT+SP     +K LTA GI FV  + R  + +      LE  +
Sbjct: 2   MYKAVFSDFNGTLLTSQHTISPRTVVVIKRLTANGIPFVPISARSPLGILPYWKQLETNN 61

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            ++  +GA + + +   I++  ++     ++  V+ ++P +  N Y +++    R    +
Sbjct: 62  VLVAFSGALILNQNLEPIYSVQIEPKDILEINTVLAEHPLLGVNYYTNNDCHA-RDVENK 120

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
              ++ +V +  ++    +      K         + +   + +       +++  S   
Sbjct: 121 WVIYERSVTKIEIHPFDEVATRSPHK--IQIIGEAEEIIEIEVLLKEKFPHLSICRSHAN 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LEVM    +KG A+  +    G    + IAFGD  ND +ML   G G  MG+A   +K 
Sbjct: 179 FLEVMHKSATKGSAVRFLEDYFGVQTNEVIAFGDNFNDLDMLEHVGLGVAMGNAPNEIKQ 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                 V  TN +D +   L + +
Sbjct: 239 AAN--VVTATNNEDGLALILEEKF 260


>UniRef50_C3WAR4 Hydrolase n=1 Tax=Fusobacterium mortiferum ATCC 9817
           RepID=C3WAR4_FUSMR
          Length = 260

 Score =  255 bits (653), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 70/262 (26%), Positives = 128/262 (48%), Gaps = 5/262 (1%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           + V SDLDGTLL   + +S Y   T+  L  + +NF  ATGR    V  I   L I  Y+
Sbjct: 2   KFVVSDLDGTLLHSHNIVSEYTIRTIDKLVKKNVNFAIATGRGQQGVQGILKQLGINPYL 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I +NGA ++  +G  I    + + I +++   +  N ++  + + ++ +F ++  P E  
Sbjct: 62  ICNNGANIYTPEGECILDKRIPKKIVTEILKEIRKN-NLFYSAFLNEFYFHSKDEPVEDF 120

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
             +    + A+ +   +    ++K+  + D+ + L+ L   +  ++     +  S  TC+
Sbjct: 121 TSRPLFTEVAVEKEEDIP--DLNKIIVSDDNPKVLIELVNILKNKFSHLAEIMLSQPTCI 178

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           ++     +KG  +E +A+    +  D +AFGDG ND +ML   G   IM ++ + LKD  
Sbjct: 179 DIAPKNCTKGTGIENLARIFNLTPDDFMAFGDGENDLDMLKTVGHPVIMENSQELLKDF- 237

Query: 243 PELEVIGTNADDAVPHYLRKLY 264
               V  +N +D V  YL K +
Sbjct: 238 -FSNVTLSNKEDGVARYLEKFF 258


>UniRef50_Q03GE4 Predicted hydrolase of the HAD superfamily n=2 Tax=Lactobacillales
           RepID=Q03GE4_PEDPA
          Length = 270

 Score =  255 bits (652), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 7/268 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI---K 59
           +++A D+D TLL+ +  L P  K+ +       +  V  +GR    V    + L I    
Sbjct: 4   KLIAIDVDDTLLNSNIVLLPSTKDIIAKCLQNHLKVVLCSGRPLAGVKPFLNELGITADD 63

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            Y+IT NG+ +  + G +I +H L   +   +             + RD   + +     
Sbjct: 64  QYVITYNGSVIESVTGEVIASHELSNSVYRAMDEFSRKYHVAYNVLDRDSNIYTSNLEVN 123

Query: 120 EMRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
                +  E      +  P  L  +             +L  +E+A++A + D+  V  +
Sbjct: 124 RFTVVQAWENKAGLLIKTPDQLPADFTITKGIFVGETAELNQVEEAVHAAFDDQCYVVRA 183

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LEVM   V+KG AL+ +++KLG   ++ IAFGD  ND  M    G    M +    
Sbjct: 184 ADNFLEVMHKNVNKGAALKTLSEKLGIHPEEIIAFGDEQNDIPMFDFVGTAVAMENGSDL 243

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYL 265
            K       +  +N  D + + L KL  
Sbjct: 244 AKSHADM--ITSSNDADGIKNALEKLIF 269


>UniRef50_D0BM40 Cof family protein n=2 Tax=Granulicatella RepID=D0BM40_9LACT
          Length = 272

 Score =  255 bits (652), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 68/272 (25%), Positives = 113/272 (41%), Gaps = 12/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGIN--FVFATGRHHVDVGQIRDNLE- 57
           M +++A D+DGTLL+    L    K+  K    +      V  TGR    +     +L  
Sbjct: 1   MIKLIAIDMDGTLLNSKKQLLEETKQYFKEFHHKDTETLLVLCTGRPETGIRPYLKDLGY 60

Query: 58  --IKSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN 114
                Y+I+ NGA +++   GN I    +D         +  ++ DI       D ++  
Sbjct: 61  LEENHYIISQNGANIYESQTGNRIMDAFVDSSAIQKWIQLGKEH-DISVMGGGVDYYYSF 119

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEP--EGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
              P E   +   +    +    + E       K+       EQL   E+ I   W D  
Sbjct: 120 DQEPTEWMEYDVKIINGEIKRITIEESLTTDFYKILLLG-DEEQLNEFEKMIPDSWRDEF 178

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            V  S    +EV+  G++K + L+ +A+KL  +  +  A GD  ND EML  AG    MG
Sbjct: 179 YVVRSQKYLIEVLKKGINKAYGLKKLAQKLNITRNEIAAIGDAANDIEMLQYAGLAIAMG 238

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A + +K+L     V  TN ++ V   + ++ 
Sbjct: 239 NATEEVKNLCDI--VTDTNENNGVIKAIERVI 268


>UniRef50_Q042H4 Predicted hydrolase of the HAD superfamily n=11 Tax=Lactobacillus
           RepID=Q042H4_LACGA
          Length = 286

 Score =  254 bits (651), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 62/271 (22%), Positives = 117/271 (43%), Gaps = 11/271 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI---K 59
           +++A DLDGTLL+    +S   +E L+  +  GI  V  +GR    + +  D L++    
Sbjct: 19  KLIAVDLDGTLLNDKQEISVKTREALQKASRLGIKIVPCSGRPFPGIKEYLDQLDLQDPN 78

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            Y++  NGA V +  GN +    L        F  +        ++   D++    H   
Sbjct: 79  QYVVAFNGALVLNAQGNAVVEELLSYQDFL-FFEKIAQQLKANFHIEVSDKFITLDHFIN 137

Query: 120 EMRFFKEAVFQYALYE---PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                +  + + ++       + +    +K  F+    E +  + + +     ++ NVS 
Sbjct: 138 YYLSRESWLTRMSIEVCGFKDIAKDLKFTKAMFSGAPSE-MERVYRHLPKEVIEKYNVST 196

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG-KGCIMGSAH 235
           S  T +E+ +   SKG+AL+ +A+KL     + + FGD  ND  M  +       MG+A 
Sbjct: 197 SDKTLIEINSKQASKGNALKELAQKLNLRQDEIMIFGDQKNDISMFDVPDFYKVAMGNAV 256

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K       V  TN +D + + +R+L  +
Sbjct: 257 LEIKKRAN--YVTRTNNEDGIAYAIRRLIFN 285


>UniRef50_B9EBT4 Putative uncharacterized protein n=1 Tax=Macrococcus caseolyticus
           JCSC5402 RepID=B9EBT4_MACCJ
          Length = 269

 Score =  254 bits (651), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 62/268 (23%), Positives = 118/268 (44%), Gaps = 9/268 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
           Y+++  D+D TLL+  + + P     L      G   V A+GR    +    + L++ + 
Sbjct: 3   YKLIVLDMDDTLLTSKNEILPSTINALIEAQNNGAMVVLASGRPTGGMIDAAEILQLDTH 62

Query: 61  --YMITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+I+ NGA V  ++   ++ A  + +   S++   +    +I+   Y+D+  +     
Sbjct: 63  QSYIISYNGAVVTRMNDRTVVDATYVQQVHFSEILHFLRK-ENIMALTYKDNTIYYEGQS 121

Query: 118 PEEMRFFKEAVFQYALYE-PGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             E    +    +    +    +  E V KV       E +  L + +   +G  ++ + 
Sbjct: 122 AYEQVEGELTGLEMIKVDNLQTVITEDVPKVMGVG-DIEHIALLNKQLEGSFGSDIHATT 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE M   VSKG  L+ +A++LG    + IAFGD  ND +ML  AG G  MG+A+ 
Sbjct: 181 SKPFFLEFMHRDVSKGKVLQRLAEQLGIQQSEIIAFGDSNNDKDMLEFAGLGVAMGNAND 240

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +K+      +  ++ +D +   +    
Sbjct: 241 TIKEAAD--VITLSHDEDGIAQIIETYL 266


>UniRef50_A9VQD5 Cof-like hydrolase n=72 Tax=Bacillus RepID=A9VQD5_BACWK
          Length = 319

 Score =  254 bits (650), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 63/288 (21%), Positives = 117/288 (40%), Gaps = 31/288 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGTLLS +  +S    + ++     G   +  +GR   D  ++ +  ++   +
Sbjct: 31  KLIALDMDGTLLSSNLEISKENLQAIQTAKEAGHIVMICSGRAKEDALKLLEEYKLSLPV 90

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR----- 117
             SNGA V+ +DG +I +  L  D    L  ++ ++      +Y +   +          
Sbjct: 91  GASNGAIVY-VDGKVINSRCLQNDKVYKLAKLL-ESEGFPYKLYTNKGVYSPYTWQDQVM 148

Query: 118 --------------PEEMRFFKEAVFQYALYEPGLLEP------EGVSKVFFTCDSHEQL 157
                          E  R  ++      + +   +E         +SK F    +    
Sbjct: 149 QAFEENKHTLDVTLEELERITEKQKKSNLITDFQKIEDVVNNPELEISKFFILTFNAAHR 208

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
             L Q +       ++V+ S  T +E+M     KG+ L+ +A      ++D +A GD  N
Sbjct: 209 SQLLQTLQE--DTDISVTASAPTNVEIMDKHGHKGNGLQEMAAYFNIPIEDTVAIGDNFN 266

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           D  ML +AG    MG+A + +K L     V  TN +  V H + +  L
Sbjct: 267 DVPMLQVAGLSVAMGNAEEDVKKLCD--VVTLTNNEHGVAHAIEQFVL 312


>UniRef50_A5CYL3 Predicted hydrolase n=5 Tax=Clostridia RepID=A5CYL3_PELTS
          Length = 274

 Score =  253 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 68/266 (25%), Positives = 109/266 (40%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           +++VA D+D TLLS D  L+   +E +  + A G+ F  +TGR +         L +   
Sbjct: 13  FKLVAVDMDDTLLSRDLKLTGRVREAVAAVRAAGVYFTISTGRMYRSALPFARELGLNIP 72

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +IT  GA V +   G L+    L    A ++   +++      N Y DD   + R  PE 
Sbjct: 73  LITYQGALVKNSHTGELVLYRPLPLARAREIIARIHE-LGYHLNGYLDDRLLVERDTPEG 131

Query: 121 MRFFKEAVFQYALY-EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
            R+   +  +  +  +          KV    +    L  L   +   +  +V++  S  
Sbjct: 132 RRYAAMSGVEAEIVGDLLEYLDRDPIKVLTIAEEP-LLDRLSAELTPLYRGKVHIVKSKP 190

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             LE      +KG AL  +A   G   ++ +A GD  ND EML  AG G  + +A + +K
Sbjct: 191 HFLEFSHPQATKGDALAYLAGCFGVKREEVMAVGDSYNDLEMLEYAGLGVAVANAREDVK 250

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
                  V      D V   L K  L
Sbjct: 251 KKA--GYVTSAAYGDGVVEALEKFVL 274


>UniRef50_Q8ELU0 Hypothetical conserved protein n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8ELU0_OCEIH
          Length = 294

 Score =  253 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 71/287 (24%), Positives = 123/287 (42%), Gaps = 30/287 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ASDLDGTLL  D T+S   ++ ++    +GI F+ ATGR +       +   I   +
Sbjct: 2   KLIASDLDGTLLQEDGTISEANQKAIQAAIDKGIEFIVATGRSYDAARIPLEKAGIDCSV 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM--------- 113
           I+ NGA  +  +  +I +  L++D+A  +  V  D   +   ++ +   +          
Sbjct: 62  ISLNGAVSYTKEKEIIRSIPLEKDVAKQITDVC-DQEGMYIELFTNKGIYSGSREYFLEV 120

Query: 114 ---------NRHRPEEMRFFKEAVFQYALYEP-------GLLEPEGVSKVFFTCDSHEQL 157
                         +++R   E  FQ+   E               V K+       EQL
Sbjct: 121 MVDIMTSANPNISEKDVREQAERRFQFEPVEFINDYHAVLDSTDINVYKILVFATEPEQL 180

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
               + + +  G  V ++ S    LE       KG A+E   ++  ++++D ++ GD  N
Sbjct: 181 SNASEKLRSEEG--VVITSSGEINLEFNHPEAQKGLAVEQYVQQKQWTMEDVMSIGDNWN 238

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           DA ML MAG+G  MG+A   +K L        TN +D V   L ++ 
Sbjct: 239 DASMLQMAGRGVAMGNAADEIKALC--SYTTLTNREDGVAVALEEML 283


>UniRef50_B2S2N8 Putative uncharacterized protein n=1 Tax=Treponema pallidum subsp.
           pallidum SS14 RepID=B2S2N8_TREPS
          Length = 277

 Score =  253 bits (649), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 61/272 (22%), Positives = 106/272 (38%), Gaps = 16/272 (5%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V +D+DGT L  ++ + P  K+ +K L  + I FV ATGR    V +    L++   +
Sbjct: 7   RLVVTDMDGTFLDSENNIPPENKQAVKCLHEKNIPFVIATGRMLPMVQEYVRQLQLVGPV 66

Query: 63  ITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +  NG  + ++  G  IF      +  + +      +  +   VY  D  +   +     
Sbjct: 67  VGYNGGMIREIKTGKTIFQKCFAAEAFARVLEYGMAH-RLDYLVYTSDSVYAPDYSVRIR 125

Query: 122 RFFKEA----------VFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
            F +            +  + +          V K+     S   L    + I +  G  
Sbjct: 126 AFHEYNRLARRGGSALIPIFPIEALSGDRQRQVMKILVQNFSPSDLETAAEFIGSLHG-- 183

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           V+   S    ++VM  GV KG+AL  + +  G SL+    FGD  ND  M   AG    M
Sbjct: 184 VHCEHSMPHLIDVMPEGVDKGNALHILCQYYGISLEQVCVFGDQRNDIVMFKAAGVSFCM 243

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            + H+  K       +  +N D      L++ 
Sbjct: 244 RNGHEEAKKHA--TYIAESNDDAGFAQALKRY 273


>UniRef50_UPI000196CFC2 hypothetical protein CATMIT_02842 n=1 Tax=Catenibacterium mitsuokai
           DSM 15897 RepID=UPI000196CFC2
          Length = 262

 Score =  253 bits (648), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 69/266 (25%), Positives = 126/266 (47%), Gaps = 10/266 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQ + SD+DGTLL+ DH +SP  ++ +K L    I F+  + R    +  I    +I  
Sbjct: 1   MYQCILSDIDGTLLTDDHHMSPKTRDAIKSL---DIPFLPVSARSPEGIYPILKENDIVC 57

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFMN-RHRP 118
            MI  +G  + D  GN+++ + ++     ++   + +   D   N+Y   +W +  +  P
Sbjct: 58  PMICFSGGLILDEKGNVLYENGMNYKQTEEVITFIKEKKFDCTINIYSLHDWLVEDKEDP 117

Query: 119 EEMRFFKEAVFQYALYEPGLLEP-EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
             +R  +    +        L+    + K+   C+       +E+++  R+    +++ S
Sbjct: 118 RVLREERIVKAEAQKGTLSSLDSSRKIHKLLCMCNPL-YTKEIEKSLKERFP-HCSIACS 175

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
           +   +E+M  GV+K  A+  +        KD +AFGD  ND EML   G G  MG+A   
Sbjct: 176 SDILIEIMNEGVTKADAINHLCDYYSIDKKDIVAFGDNYNDKEMLESVGMGIAMGNAPDD 235

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKL 263
           +K++    +V  TN  D + + L+KL
Sbjct: 236 IKNIA--RDVTSTNNQDGIFNALQKL 259


>UniRef50_C5NUB3 Hydrolase n=3 Tax=Firmicutes RepID=C5NUB3_9BACL
          Length = 430

 Score =  253 bits (648), Expect = 5e-66,   Method: Composition-based stats.
 Identities = 60/289 (20%), Positives = 119/289 (41%), Gaps = 29/289 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASD+DGTLL+ +H +     + +     +GI FV ATGR + +     +   I  
Sbjct: 1   MIKLIASDMDGTLLNHNHKIPKENVKLINFAKNQGIEFVVATGRAYYEALPALNEENINC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWF---MNRHR 117
            +I+ NG  V+D +GN+I    +          ++    DI   +Y  +  +   +    
Sbjct: 61  DVISFNGGIVYDKNGNIISITPMLPKDLYYTIEILKSF-DISYQLYTKNTIYTTSIETDT 119

Query: 118 PEEMRFFKEAVFQYALYEP----------------------GLLEPEGVSKVFFTCDSHE 155
              +   +   ++  +                            +     K+    +   
Sbjct: 120 NAYIDLIRSNGYEPDVEHLRAEAQQKLEVGYITEVENIELYLNEKENPPIKIIAISNDIS 179

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           +L    + ++      ++V+ S    +E+M    +KG AL+ +AK  G +L++ +A GD 
Sbjct: 180 KLENAAKLLSENTS--ISVTSSGANNIEIMHKNATKGTALKEIAKIYGINLENAVAIGDN 237

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +ND  ML + G    M + + +LK+    +    TN++  V   + KL 
Sbjct: 238 LNDQAMLDIVGYSVAMKNGNIKLKEQAKYVTE-KTNSEGGVADTIFKLI 285


>UniRef50_D0A841 Haloacid dehalogenase-like hydrolase, putative n=2 Tax=Trypanosoma
           brucei RepID=D0A841_TRYBG
          Length = 287

 Score =  253 bits (647), Expect = 5e-66,   Method: Composition-based stats.
 Identities = 107/272 (39%), Positives = 153/272 (56%), Gaps = 9/272 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-S 60
           Y+    DLDGTLL+ +H +S Y  +T++ L  R I  V ATGR H DV     +  ++ +
Sbjct: 12  YRAAVVDLDGTLLNENHRISAYTLDTIQKLLKRNIPVVIATGRPHPDVFHTIKSCGLQGT 71

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDI--------ITNVYRDDEWF 112
           Y+ITSNGARV D   N+I + NL  D+ S+L G+ +   DI          N+++ DEW 
Sbjct: 72  YVITSNGARVSDPQLNVIASFNLSEDVVSELIGLGSSGEDIQDPKEVPYTVNLFQHDEWV 131

Query: 113 MNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
            +  R E ++ F  + F Y + +      +              L  LE  +  R+  R+
Sbjct: 132 TDAAREELLQMFASSGFHYRVVDDLQAHQKDGVHELVFLAQPNTLHLLEGVVKKRFEGRI 191

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           +V  ST   L+V+    +K  A+  VA+ LG  LKD ++FGDGMND +ML+ AGKG IMG
Sbjct: 192 SVMRSTSITLDVVHHNANKATAMAKVAELLGLELKDIVSFGDGMNDVQMLAAAGKGYIMG 251

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A QRLKD  P LEVIGTNA+D+V   LR+L+
Sbjct: 252 NAQQRLKDALPHLEVIGTNAEDSVAKKLRELF 283


>UniRef50_D2RIN9 Cof-like hydrolase n=2 Tax=Acidaminococcus RepID=D2RIN9_ACIFE
          Length = 269

 Score =  253 bits (647), Expect = 6e-66,   Method: Composition-based stats.
 Identities = 67/264 (25%), Positives = 114/264 (43%), Gaps = 8/264 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLL  +  ++P     +K   A G     ATGR +         L +   +
Sbjct: 4   KMIAMDLDGTLLDEEKNIAPEDAAAVKDAVAAGYYVTLATGRMYRSALPYAQELRLTHPL 63

Query: 63  ITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +  NGA + D   G  +    L  D+A  +   +     I    Y DD  +  R   E  
Sbjct: 64  VVYNGALIRDPGTGENLGQWPLPLDVAQSVLDDLL-GWGIYVQAYVDDTLWAPRDCEEVR 122

Query: 122 RFFKEAVFQYALYEPGLLE-PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            + + +   Y +    +   P+   K+    D   Q+  L   +  ++  ++ +  S+  
Sbjct: 123 FYSRFSRVPYEVKTEAIRHLPQAPHKLLVISD---QVRTLRPELEEKYRGKIKIVSSSKG 179

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LEV A G +K HAL+A+A + G   ++ +  GD  ND EM+S AG G  MG+A   +++
Sbjct: 180 FLEVTAPGTNKWHALQALAAREGIREEEILCVGDSDNDLEMISHAGFGVAMGNASDPVRE 239

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                 V   N  + V   +R + 
Sbjct: 240 AA--RVVTAPNTRNGVARIIRTIL 261


>UniRef50_Q04BG8 Predicted hydrolase of the HAD superfamily n=13 Tax=Lactobacillus
           RepID=Q04BG8_LACDB
          Length = 294

 Score =  252 bits (646), Expect = 6e-66,   Method: Composition-based stats.
 Identities = 63/290 (21%), Positives = 109/290 (37%), Gaps = 31/290 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++  DLDGTLL+    +S    + +K     GI F+ A+GR   +   +     I  
Sbjct: 1   MIKLITCDLDGTLLNSSMEISDANVQAIKRAQENGIEFMVASGRAPHESQPMLKEYWIDC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             I  NG  V D  GNLI  + L  + A  +  ++         +   +  +        
Sbjct: 61  SFINLNGGLVFDTAGNLIVKNPLKLETAKKICRLLKK-EGFYFELVTSNHVYSEDLSQRI 119

Query: 121 MRFFKE------------------------AVFQYALYEPGLLEP-EGVSKVFFTCDSHE 155
                                         ++ Q   YE  + EP   V K+       +
Sbjct: 120 TNVAHLMVELNPMLTFKEAVLVSASKPAIVSIQQVPSYEDLMDEPGTEVMKILVFDSRGQ 179

Query: 156 QL-LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGD 214
                + + I     D+++++ S    +E+ A    KG +L   A   G   ++  A GD
Sbjct: 180 YAFTDVIKKIEEI--DKLSITSSAADNIEINAASAQKGQSLLDYAAAKGIKREEIAAIGD 237

Query: 215 GMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +ND  M+  AG G  MG+A  ++K +     V  +N +D V   + K+ 
Sbjct: 238 NLNDESMIQAAGTGVAMGNAVPQIKTIA--SFVTKSNNEDGVAWAIDKII 285


>UniRef50_Q737I7 Hydrolase, haloacid dehalogenase-like family n=61 Tax=Bacillus
           cereus group RepID=Q737I7_BACC1
          Length = 283

 Score =  252 bits (646), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 60/287 (20%), Positives = 118/287 (41%), Gaps = 31/287 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLLS +  +S    E ++     G      TGR  +D+ ++   + ++  +
Sbjct: 2   KLIAIDLDGTLLSGNKMISNENAEAIRKCQEAGHVVAICTGRSIIDIERLLLEVNLECPI 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE--- 119
           I  NGA +++ D  ++  + +    A ++   + +N  +   +Y +   ++  +  E   
Sbjct: 62  IAENGALIYN-DKKMMKRYPIQNMQALEIVNYLEEN-GLYYQLYTNKGVYVPEYGVESVR 119

Query: 120 -EMRFFKEAVFQYALYEPGLLE---------------------PEGVSKVFFTCDSHEQL 157
            E+ + K +     L E   +                         V K+       E+L
Sbjct: 120 NEIDYVKHSNENIDLKELETIAALYLEHTAFLSAESCKPIVETDIHVHKLLPFSYDMEKL 179

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
             L++         + ++ S    LE+      KG+ L  +A+ L   +++ +A GDG+N
Sbjct: 180 KKLKETF--LHNTDLAITSSYWHNLEINHRDAQKGNGLYTLAEHLNIPVENTVAIGDGLN 237

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           D  M+  A     MG+A + +K +        TN +  V H L K  
Sbjct: 238 DVSMMEKANLSIAMGNAVEEIKAMC--QYETLTNEEHGVAHALYKYV 282


>UniRef50_C9RTQ8 Cof-like hydrolase n=4 Tax=Geobacillus RepID=C9RTQ8_GEOSY
          Length = 282

 Score =  252 bits (646), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 61/282 (21%), Positives = 97/282 (34%), Gaps = 25/282 (8%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A D+DGTLL+ +  +S   ++ +      G      TGR   D         +   + 
Sbjct: 2   LIALDMDGTLLNGEGKISERNRKAMMAAQKEGHIVAVITGRARKDALAPLREAGLVCPIA 61

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRF 123
           + NGA V   DG +I    L R         V    D+    Y  D  ++  H   +   
Sbjct: 62  SLNGAIVTLEDGTVIGEAPLARTAVRPTLEWVRKQSDLYCETYTGDAVYVGLHNRAQWES 121

Query: 124 FKEA-----------------VFQYALYEPGLLEPEGV----SKVFFTCDSHEQLLPLEQ 162
                                  +    +      +       K+       E+L     
Sbjct: 122 LASEMADAAPDVKWLVNKQFQQARVTYVDDIRTVWDDPQLTLYKLLIFALDRERLRDAAS 181

Query: 163 AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
              A  G  V V+ S    +E+     +KG AL+ +A   G  L D +AFGD  ND  M 
Sbjct: 182 RFAALPG--VTVTSSHPHNIEMNNERATKGEALKQLAAHYGIDLCDTVAFGDSHNDLSMF 239

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +AG    M +A   LK       V  ++ +D V   L ++ 
Sbjct: 240 EVAGCRVAMANAAPELKAKADI--VTCSHEEDGVAAGLERVL 279


>UniRef50_C4FTB9 Putative uncharacterized protein n=1 Tax=Catonella morbi ATCC 51271
           RepID=C4FTB9_9FIRM
          Length = 274

 Score =  252 bits (646), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 63/269 (23%), Positives = 114/269 (42%), Gaps = 10/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           YQ++  D+D TL++ ++T+S    + L     +G   V A+GR    + +    L++   
Sbjct: 4   YQMLVLDIDDTLMTSENTISDATYQALMKAQEQGKKVVLASGRPTPSMIETAKQLKLDHF 63

Query: 60  -SYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
            SY+I+ NGA +    DG  +F+  L+ +   D+   +     +    Y DD   M++  
Sbjct: 64  DSYIISFNGAAITSMADGQELFSQRLEAEAQDDIVRYIQAK-GLTVLTYMDDYVVMDKAN 122

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSK---VFFTCDSHEQLLPLEQAINARWGDRVNV 174
                  +            +     ++K    F      + +   +  +  R+G+    
Sbjct: 123 DYSHIESQLTGIPDRYDPEAIANLSQLAKARMKFIGVGDPDLVAAADAELEGRFGELTYA 182

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           + S    LE +   VSKG A++ + + LG +L   IA GDG ND  M+  AG G  M +A
Sbjct: 183 TTSKPYFLEFVHHQVSKGQAIKVLCQHLGLTLDQVIACGDGNNDLTMIETAGLGVAMANA 242

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKL 263
              LK+      +  +N  D +   +R  
Sbjct: 243 TPLLKEAADH--ITLSNDQDGLVPIIRDF 269


>UniRef50_Q5WGE2 HAD superfamily hydrolase n=2 Tax=Bacillus RepID=Q5WGE2_BACSK
          Length = 289

 Score =  252 bits (646), Expect = 7e-66,   Method: Composition-based stats.
 Identities = 69/287 (24%), Positives = 114/287 (39%), Gaps = 29/287 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++ +D+DGTLL    ++S   +E +K    +G     ATGR   +         +   +
Sbjct: 2   KLIVTDMDGTLLDEKRSVSKENEEAIKAAQKQGAVVAIATGRDLYEATVPLKKTGLSLPI 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH------ 116
           I++NGA++HD  G L+    L  D A     V+  N ++   VY ++  + +        
Sbjct: 62  ISANGAQIHDEHGRLLHEAVLSPDQARHAMAVLK-NENVYFEVYTNEGVYSDDFEAGLAV 120

Query: 117 ------------------RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLL 158
                                + RF   ++     YE  L +   V K+       ++L+
Sbjct: 121 VVDVLKSTGAKLSEQEIMTFAKDRFDNGSIKLIDCYEKLLEDGAVVLKLLAFSLDAKRLM 180

Query: 159 PLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND 218
                +         VS S    LE+      KG A+E +A+ LG S KD +A GD  ND
Sbjct: 181 SARDRLE--LDKNFAVSASAADNLEITDVNAQKGIAVERLAQSLGISPKDVMAVGDNFND 238

Query: 219 AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             M   AG    MG+A   ++       V  TN +  V + +R   L
Sbjct: 239 VSMFQKAGLAVAMGNAPGEIQKQADL--VTKTNDEHGVAYAIRNYAL 283


>UniRef50_A7VNH3 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VNH3_9CLOT
          Length = 272

 Score =  252 bits (646), Expect = 8e-66,   Method: Composition-based stats.
 Identities = 64/269 (23%), Positives = 111/269 (41%), Gaps = 9/269 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
           Y+++A DLDGTL++    ++  AK+ +      G     A+GR    +     +L +   
Sbjct: 3   YRLLALDLDGTLVTSHGGITEAAKQAVWSYIDAGGVVALASGRPTRGLWP-AQDLRLAQK 61

Query: 59  KSYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+++ NG ++ +   G  I+  ++ +D+   +  ++ D   +    Y+D    +    
Sbjct: 62  GGYLLSYNGGKIVNCKTGAAIYEKDIPQDLVPVIIRMIRD-AGMEAISYQDQYVLLEHVD 120

Query: 118 P-EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                R       +Y                   C + EQ+L LE+      G RV+V  
Sbjct: 121 RLWFDREASVCRMEYKEVPDLAAYVTFPVVKLMACGAPEQILALEKQAQEAIGSRVDVFR 180

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE +A G+ K   LE + K LG +     AFGD  ND  M+  AG G  M ++  
Sbjct: 181 SEDFYLEFVAKGIDKAATLEVLLKHLGLTRDSLAAFGDSYNDIPMIKYAGFGVAMANSIP 240

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +        V  +N +D V H + +  L
Sbjct: 241 EVLQAADA--VTKSNDEDGVAHAIYRYLL 267


>UniRef50_C6W4G6 Cof-like hydrolase n=1 Tax=Dyadobacter fermentans DSM 18053
           RepID=C6W4G6_DYAFD
          Length = 265

 Score =  252 bits (645), Expect = 8e-66,   Method: Composition-based stats.
 Identities = 59/262 (22%), Positives = 111/262 (42%), Gaps = 4/262 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA+D+DGTLL+  H +        + L   GI FV A+GR + ++ +  D ++ +  
Sbjct: 6   IRLVATDMDGTLLNSKHEIHESFFPVFRKLRDHGIIFVAASGRQYFNLAKTLDAVKEEVI 65

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
               NG+ V   +   I    +D++I  +L  V     +    +    + ++     E +
Sbjct: 66  FAAENGSYVV-CNDEEIHIQAVDQEITHELIRVARKIKNTYPIICGKKKAYVENDDEEFI 124

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
              K    +Y + E  L   +     F  CD     +         + + + V  S    
Sbjct: 125 NHLKLYFERYEVVEDLLEIRDDQFLKFTLCDLAGSEVNSYPHYKK-YENDLQVKVSGPIW 183

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           L++     +KG A+E + +K   + K  + FGD +ND EML  A     M +AH  +K +
Sbjct: 184 LDISHKKANKGRAMEVLQEKFNITAKQTMVFGDYLNDLEMLEKAHYSYAMANAHPDIKKI 243

Query: 242 HPELEVIGTNADDAVPHYLRKL 263
                +  +N ++ V   L ++
Sbjct: 244 A--RFIAKSNDENGVVEVLSEI 263


>UniRef50_Q4KBY5 Cof-like hydrolase family protein n=8 Tax=Pseudomonas
           RepID=Q4KBY5_PSEF5
          Length = 270

 Score =  252 bits (645), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 73/260 (28%), Positives = 113/260 (43%), Gaps = 3/260 (1%)

Query: 7   SDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSN 66
           SD+DGTLL PDH+LSP   + ++ L   G+ F  ATGR    + Q  + L +       N
Sbjct: 11  SDMDGTLLRPDHSLSPRTLDAVRALREAGVAFSLATGRPPRAMLQQIEALGVDLPTAGFN 70

Query: 67  GARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKE 126
           G  +   DG+ +  H++  + A     +    P + T V+ D+EW +       M   ++
Sbjct: 71  GGSIVKPDGSFLARHHVPVEAAVTALLLFEPCPQVETWVFADNEWLLRNLDGALMPLERQ 130

Query: 127 AVFQYALYEPGLLEPEG-VSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLEVM 185
           A+           E    + K+      H  L+ LE  + A    +   S S    L++ 
Sbjct: 131 ALGYAPKVVDSFEEYLPRIDKIVAASSDHRLLVQLEARLQAATAGQAQASRSQPRFLDLT 190

Query: 186 AGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPEL 245
           A    KG AL  +A+ LG  L+   A GDG ND  M   AG    MG A +R+K      
Sbjct: 191 ALQADKGQALVTLAEYLGVPLERTAALGDGGNDPAMFQRAGLSIAMGQAEERVKRQAD-- 248

Query: 246 EVIGTNADDAVPHYLRKLYL 265
            + G+N +D     + +  L
Sbjct: 249 VITGSNLEDGAAEAIERYIL 268


>UniRef50_A7ZIK4 HMP-PP phosphatase n=87 Tax=Bacteria RepID=COF_ECO24
          Length = 272

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 101/264 (38%), Positives = 145/264 (54%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M ++ A D+DGTLL PDH L      TL  L  R I   FATGRH +++  I   L + +
Sbjct: 1   MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDA 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+IT NG RVH L+G L+   +L  D+A +L      +     +++ DD WF  +  P  
Sbjct: 61  YLITGNGTRVHSLEGELLHRDDLPADVA-ELVLYQQWDTRASMHIFNDDGWFTGKEIPAL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++ F  + F+Y + +   +    V+K+ F C  H+ L  L+  +    G+R ++ FS   
Sbjct: 120 LQAFVYSGFRYQIIDVKKMPLGSVTKICF-CGDHDDLTRLQIQLYEALGERAHLCFSATD 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEV+  G +KG AL  + + LG SL+DC+AFGD MND EML   G G IMG+A  +L+ 
Sbjct: 179 CLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRA 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
             P L VIG   + AV HYL    
Sbjct: 239 ELPHLPVIGHCRNQAVSHYLTHWL 262


>UniRef50_C2M275 Sugar phosphatase SupH n=1 Tax=Capnocytophaga gingivalis ATCC 33624
           RepID=C2M275_CAPGI
          Length = 267

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 54/260 (20%), Positives = 107/260 (41%), Gaps = 3/260 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ SD+DGTLL+ +H L        + L  RGI F  A+GR ++ +      ++ K 
Sbjct: 1   MIKLIISDMDGTLLNSNHELPQDFMHVFETLQERGIYFCVASGRQYLSLLSFFAPIKDKM 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             I+ NGA V  ++G  ++ + +       +         +   +      ++    P  
Sbjct: 61  AFISENGAFV-SINGKEVYQNAISPYHIQQVVARYKQFSGMAIGLCGKKATYLLPTTPYA 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                                + +S++    D          A ++   + + ++ S   
Sbjct: 120 EEQVNIYHHTVEKVTDLSQIDDTISQITIL-DPIGAREHSFPAFSSLSQEGLKITISGAY 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            +++   GV+KG A+ A+ + LG S ++ +AFGD +ND E+L  A     M +A + +K 
Sbjct: 179 WIDITNEGVNKGVAVTALQEFLGISPEETMAFGDYLNDLELLKRASYSYAMKNAQEEVKQ 238

Query: 241 LHPELEVIGTNADDAVPHYL 260
           +    E    N  + V   +
Sbjct: 239 VA-FYETKDDNNHNGVLKTI 257


>UniRef50_B6FMU0 Putative uncharacterized protein n=1 Tax=Clostridium nexile DSM
           1787 RepID=B6FMU0_9CLOT
          Length = 269

 Score =  252 bits (644), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 63/272 (23%), Positives = 128/272 (47%), Gaps = 12/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+D T ++  H ++   KE L+ + A+GI+ V  TGR    +      +E  S
Sbjct: 3   MIKLLAVDMDETAVNSRHRMTKVTKEALREVYAKGIHVVPVTGRCLEGLPANMRGMEELS 62

Query: 61  YMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
           Y+ITSNGA+V+D  +  +++   +  + A D+  +   +  +   ++++ + + N     
Sbjct: 63  YIITSNGAKVYDWKEKEVLYRKLISNETACDVLKICQQDA-LGIAIHQEGKCYDNSKVQA 121

Query: 120 EMR---FFKEAVFQYALYEP---GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
             R   +  +   + A+ +         + + K+       E+L  ++  +     D + 
Sbjct: 122 LYRKLAYHGDFKMREAIKDLCGFVKKSGKPIEKIQVFSGKKEKLESIKNKLEP--FDDLE 179

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           ++ ST   +E+      KG ALE + + LG  +++ +A GD  ND  ML  AG    MG+
Sbjct: 180 LAISTSGYIEITQKDAQKGKALEHLCRYLGIHMEEVMAIGDNENDHSMLVRAGYPIAMGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A++ +K +     V  +N +  V   + +  L
Sbjct: 240 ANEEIKKIAK--YVTASNDESGVAKAIYEKLL 269


>UniRef50_C4VRW0 Phosphatase YidA n=1 Tax=Lactobacillus gasseri 202-4
           RepID=C4VRW0_9LACO
          Length = 272

 Score =  251 bits (643), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 61/273 (22%), Positives = 112/273 (41%), Gaps = 12/273 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            ++VA DLDGTLL+ +  + P + + L+ ++ +G+  V  TGR  + V      L + + 
Sbjct: 3   IKLVAIDLDGTLLNDEGKILPNSIKVLRQISHKGVKVVLTTGRPLISVKPFLKELNLDAS 62

Query: 61  ---YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              Y+IT NGA + +  G  I     D     D F +  +N ++   +   +  +     
Sbjct: 63  SHQYVITFNGAIIENTQGKTIKEAAFDIQTFID-FELWANNINLYNQLETPNFLYTTYTN 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVF-----FTCDSHEQLLPLEQAINARWGDRV 172
                  +    +  +    L +   +SK             E+L  ++  I     +++
Sbjct: 122 IPIEAAHESWKNKLPMKVKTLHDLIEISKKLVLLKIMAVGDKEELDRVQNNIPQSILEKL 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           N   S    L+  A  + KG AL+ +A+ L     + +A G+  ND  M+  AG G  M 
Sbjct: 182 NPIRSEPEYLDFAAPNIDKGWALKKLAEYLDLIPSEIMAIGNADNDIPMIKYAGTGIAMA 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           S+   L  +        +N  D +   ++K  L
Sbjct: 242 SSTPTLLKIADYK--TASNNIDGIEKAIKKFIL 272


>UniRef50_D1AMP5 Cof-like hydrolase n=2 Tax=Fusobacteriaceae RepID=D1AMP5_SEBTE
          Length = 265

 Score =  251 bits (643), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 94/267 (35%), Positives = 145/267 (54%), Gaps = 4/267 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY+ V +DLDGTLL+ +  +S ++KE +  +  +G+ F  ATGR + D  +I + + IK 
Sbjct: 1   MYRAVVTDLDGTLLNNEKEVSEFSKEVINKIREKGVKFFIATGRSYPDTKRIMETIGIKV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPD--IITNVYRDDEWFMNRHRP 118
            +ITSNGAR++D +G  I+A++L++     +  +        I  N+Y D+ W++     
Sbjct: 61  PLITSNGARINDENGETIYANDLEKKYIRKILEMDYKKYGEEIFLNLYSDNVWYITEEMT 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
               F     F          +   VSK FF    HE L+ LE+ +       VN++  T
Sbjct: 121 -MDPFKDLKYFLPHKITVEEAKQMSVSKFFFIG-DHEHLMRLEKELFLLTDGNVNIAMVT 178

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
             CLEV    V KG+A++ + KK    + + +AFGDG ND EML M GKG +MG+A  +L
Sbjct: 179 PECLEVFDIEVHKGNAIKILMKKEKIKMSEVVAFGDGFNDYEMLKMVGKGYVMGNALYQL 238

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K+  P+ E+IGT   DA    L +L+L
Sbjct: 239 KEALPDNEIIGTCDSDAEAKKLIELFL 265


>UniRef50_C7XLV6 Putative uncharacterized protein n=1 Tax=Lactobacillus crispatus
           125-2-CHN RepID=C7XLV6_9LACO
          Length = 273

 Score =  251 bits (643), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 61/275 (22%), Positives = 112/275 (40%), Gaps = 12/275 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A DLDGTLL+    +   + + +K     GI  V  TGR  V V    + L++  
Sbjct: 1   MIKLIAIDLDGTLLNDHGEILQNSIKAIKEAKNYGIKIVLCTGRPLVSVTPFLEQLQLTN 60

Query: 59  --KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
               Y+IT NG+ +    G +I     D     D F +  D   + T +   +  +    
Sbjct: 61  FNDQYVITFNGSIIETTAGKVIKQQTFDFQTFVD-FELWADKIALYTQLENQEALYTINQ 119

Query: 117 RPEEMRFFKEAVFQYALY-----EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDR 171
                   +    +  ++     +   +  + V        S E+L  ++  I     D+
Sbjct: 120 NIPIDAAHESWKNKLPIHVTSLHDLIAMPQKPVMLKIMAVASKEKLDEIQHKIPNDLLDK 179

Query: 172 VNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
           ++   S    L+  A  V KG AL+ + + L  + ++ +A G+  ND  M+  AG G  M
Sbjct: 180 LSPIRSEPMYLDFAAPNVDKGWALKKLTQYLHLNRQEVMAIGNADNDVPMVKYAGVGVAM 239

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +  RL  +     + G+N    +   + K+ L+
Sbjct: 240 EKSTPRLLQVAD--YITGSNNTTGIADIINKMILT 272


>UniRef50_Q184T9 Putative hydrolase n=7 Tax=Clostridium difficile RepID=Q184T9_CLOD6
          Length = 273

 Score =  251 bits (643), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 60/274 (21%), Positives = 106/274 (38%), Gaps = 18/274 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ +D+DGTL+     +S    + LK    +GI     TGR +  +      L    Y
Sbjct: 6   YKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKIALVTGRPYNAMKYFTSVLGDDIY 65

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I++NG     L     +   L ++    ++ +     ++  +         N    EE 
Sbjct: 66  IISTNGTYFKLLGYE--YKKVLSKEALKKIYTIGEKY-NLNKHFKGCKIVISNNEIGEEH 122

Query: 122 RFFKEAVFQYALYEPGLLE-----------PEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            +              ++E              + K     ++ + L   ++    +  +
Sbjct: 123 PYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFSENVDSLREAKEEFKKQ--E 180

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + V  S     EVM+ G SKG A++     LG   ++ I  GD  ND  M+  AG G  
Sbjct: 181 DLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSEEVICIGDNENDISMIKFAGLGIA 240

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           MG+A   +K +     V  TN +D V   LRK+ 
Sbjct: 241 MGNATDEVKSMAD--FVTDTNVNDGVAKALRKIL 272


>UniRef50_C0ZHG1 Putative uncharacterized protein n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZHG1_BREBN
          Length = 289

 Score =  251 bits (642), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 69/283 (24%), Positives = 118/283 (41%), Gaps = 26/283 (9%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +VA D+DGTLL+ D  L+   KE L+ L  +G   V +TGR +       D+     Y +
Sbjct: 7   MVAFDMDGTLLTHDSKLTEGTKEALRQLQQQGCKLVLSTGRMYGSAQIPIDSFPFDGY-V 65

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDE--WFMNRHRPEEM 121
            SNG  V + DG L+    L  ++       +     I   ++  +   W +   R    
Sbjct: 66  CSNGGTVFEGDGTLVRQWLLPTEMVIGAIHALRQ-ETIYYELHDTNSNRWMIKEDRERLE 124

Query: 122 RFFKE------------AVFQYALYEPGLLEPEG-------VSKVFFTCDSHEQLLPLEQ 162
               E              ++ A  EP     E        + K F      ++L  +++
Sbjct: 125 ATMSEDASVEGFSILSFPYYRLARVEPLAEVLEKVESGEVEIVKFFVWHQDPDRLEWVKE 184

Query: 163 AINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEML 222
            +   W ++V ++ S    +EV+  GVSK   L+   +K G S +  +AFGD  ND E L
Sbjct: 185 QLKP-WSEQVTITSSGKQNVEVIPQGVSKWEGLQYFCEKWGISPEKVMAFGDAENDREAL 243

Query: 223 SMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           + AG    M +A   +K +     +   + ++ V  ++R+  L
Sbjct: 244 TGAGYSVAMENASDEIKQVAK--YIAPHHNEEGVARFIRERVL 284


>UniRef50_A5I530 HAD-superfamily hydrolase, subfamily IIB n=12 Tax=Clostridium
           RepID=A5I530_CLOBH
          Length = 274

 Score =  250 bits (641), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 57/275 (20%), Positives = 117/275 (42%), Gaps = 14/275 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+DGTLL+ +  ++      +K    +G+  V ++GR    +      +  +  
Sbjct: 3   YELIALDMDGTLLNDEKKITEKTLSYIKEAKEKGVKVVISSGRVPGGLKFYEKTIAKEEP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           MI +NGA + +     I+   ++++   ++  V+    D   + Y D+     +      
Sbjct: 63  MICANGALILNDKKETIYNEGINKNTLLNIIDVLRKYKDTYYHFYHDNIMCTEKFDYSTK 122

Query: 122 RFFKEAVFQYALY-----------EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
           + ++        Y           E        ++K+    +  + L  +++ I      
Sbjct: 123 KIYEFNKNIERKYRIEIRIITDSKEYIKHRSSEITKIVVVDNDLKYLNRIQKEIEDNL-- 180

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           +V+V+ S ++ +E+   G+SKG ALE +A      ++ CIA G+  ND  M+  AG G  
Sbjct: 181 KVSVTKSHISNIEICNFGISKGIALEKLANYYNIPIEKCIAVGNDENDISMIKKAGLGVF 240

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           M +  + LK     +     N +D +   + K  L
Sbjct: 241 MKNTREELKKYADYIT-YMDNNNDGIAEVIEKFIL 274


>UniRef50_C5RDT1 Cof-like hydrolase n=1 Tax=Clostridium cellulovorans 743B
           RepID=C5RDT1_CLOCL
          Length = 314

 Score =  250 bits (641), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 58/279 (20%), Positives = 120/279 (43%), Gaps = 19/279 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++  D+DGT+L+  H L+   K+ LK    +G++ V  +GR   D     + L + S 
Sbjct: 34  YKMICVDIDGTILNDKHKLTEDTKKALKEAHDKGLHVVICSGRLFSDAEYYSNLLGVNSS 93

Query: 62  MITSNGARVHDLDG-NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++ SNG  + D      IF   L ++  S L  + + + +I  + Y  D+ + +  +   
Sbjct: 94  IVGSNGTIIKDKKNDEFIFKKILGKNTCSKLLKIFSKH-NIKASFYTTDKVYSSNFKFTL 152

Query: 121 MRFFKEAV-------------FQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINAR 167
           + F  + +              +    +      + + K   T    ++L  L++ +   
Sbjct: 153 ILFLGKLIGVVSRNTKLKYIFNKKQWQQMIDTSVDNIYKCEVTVKDIDKLNALKKELKQL 212

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
               + +       +E+ + G++KG A++ + K      ++ I  GD  ND  M+  AG 
Sbjct: 213 H--DIELVNQAADNIEISSKGITKGSAVKFLTKYYNIKKEEVITIGDSGNDLPMIEYAGL 270

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           G  MG+A + +K+      +  +N D  V   + +  L+
Sbjct: 271 GVAMGNAFEDVKERAD--YITASNNDSGVAKVINEFVLT 307


>UniRef50_B1BZI7 Putative uncharacterized protein n=2 Tax=Clostridium spiroforme DSM
           1552 RepID=B1BZI7_9FIRM
          Length = 268

 Score =  250 bits (641), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 69/268 (25%), Positives = 119/268 (44%), Gaps = 7/268 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MYQVV SD+DGTLL+  H ++P     +K +  +GI FV  + R    +  I     +  
Sbjct: 1   MYQVVFSDVDGTLLNDQHCITPLTLLAIKKIQQQGIPFVIVSARSPSGIYPILKENNLVC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWFMNR-HRP 118
            MI   G  + + +  +I+   ++  +A  +   +  N  DI   +Y  D+W +     P
Sbjct: 61  PMICYGGGMILNHENEIIYEKGMETSLALKIINYIEANNFDIAWCIYSFDDWLVKDCLDP 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEP-EGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
             ++  +    +        ++    V K+   C +HE +  LE  +   + +   +  S
Sbjct: 121 RIIKEEQIVRAKSRQGNQIEIKKLSKVHKILCIC-NHEHINDLETKLKIMFKE-CQIVKS 178

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
           +   +E+    +SK  A++     L  ++K+ IAFGD  ND EML + G G  M +A   
Sbjct: 179 SNILIEITHQNISKAFAIKKYCDLLNINIKNTIAFGDQYNDLEMLKIVGCGIAMKNAPLG 238

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +K      +V   N  D +   L KL L
Sbjct: 239 IKKE--VKQVTKDNNHDGIYFALSKLNL 264


>UniRef50_C5RAP3 Haloacid dehalogenase (HAD) superfamily hydrolase n=1 Tax=Weissella
           paramesenteroides ATCC 33313 RepID=C5RAP3_WEIPA
          Length = 278

 Score =  250 bits (641), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 62/268 (23%), Positives = 106/268 (39%), Gaps = 6/268 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M   +A DLD TLL+    +S   +  LK L   G   V  TGR    + ++   LE+  
Sbjct: 11  MITTIALDLDNTLLNSAKEISEENERVLKQLHKMGKRIVLCTGRPIQGIQKLLTQLELFE 70

Query: 59  -KSYMITSNGARV-HDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NG  + H+    ++    + +   + L+         I  +  D  + +   
Sbjct: 71  PTDYAITFNGGLIQHNQTQRILAQTTISKHEVAALYQDAQKRHYPIDVIGADQVYSLITL 130

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
                     AV  +       L  +            E +  + + + A   D +++  
Sbjct: 131 GKSAYESTMGAVLPFTDVSFDDLPVDQTFGKAVCAAPAEVVQRVRKEMPAELNDLLHIVP 190

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE +   V+K   L  +    G +L + + FGD  ND EM++ AG G  MG+A  
Sbjct: 191 SRAELLEFLPNNVNKARGLTQLMAHFGETLDNAMTFGDEENDFEMIAQAGIGVAMGNAIP 250

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ++K +        TN +D V  YL++ +
Sbjct: 251 QIKQVAKAE--TLTNNEDGVAAYLKQYF 276


>UniRef50_A3I239 Putative uncharacterized protein n=1 Tax=Algoriphagus sp. PR1
           RepID=A3I239_9SPHI
          Length = 272

 Score =  250 bits (641), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 118/272 (43%), Gaps = 13/272 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNL-EIKS 60
            +   SD+DGTLL+ D  LSP  K  +    +     + A+ R    +  +  +L + + 
Sbjct: 3   IKAFCSDIDGTLLNADRDLSPRLKSVVNKFPS-DFPVILASSRMPNAMRHLVRDLQKPEQ 61

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            +I  NG  V   +G ++ +  +   + + +  +   N +I  ++Y+ ++W+  +     
Sbjct: 62  PLICYNGGYVISAEGEILDSVTIPVPLVAKILDLCK-NTNIHVSLYQGEDWYEEKDDYWS 120

Query: 121 MRFFKEAVFQY------ALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
            R  +             + +       G  KV    DS E +  L   ++   G+ +++
Sbjct: 121 QREIRNTKTNCTWLPGNEVVQLWSKGDSGAHKVMCMGDSQE-ISWLFGELHFEHGNDLHL 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKK-LGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
             S+ T LE+    +SK   L  +      + ++  IAFGD  ND ++L   G G  +G+
Sbjct: 180 YRSSDTYLEIAPRSISKATGLIKILDHAFDFGMESVIAFGDNYNDIDLLQSVGYGVAVGN 239

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A   +K +    E+  TN +D V   L KL+L
Sbjct: 240 ARPEVKAVAK--EITTTNKEDGVAIVLEKLFL 269


>UniRef50_Q042G1 Predicted hydrolase of the HAD superfamily n=8 Tax=Lactobacillus
           RepID=Q042G1_LACGA
          Length = 286

 Score =  250 bits (641), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 63/289 (21%), Positives = 110/289 (38%), Gaps = 31/289 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASD+DGTLL+    +S      +K   A+GI F+ ATGR   +   I     + +
Sbjct: 1   MIKLIASDMDGTLLNKQMQISSENISAIKEAQAKGIEFLVATGRAPSESQGILAKAGLHT 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             I  NGA V + +G LI    + ++ +  +  ++ D       +   D  + +      
Sbjct: 61  GFINLNGAMVFNTEGKLIVNEPIPKEESFKINKLLKD-SGFYFEIVGADHVYSDSRLRRI 119

Query: 121 MRF-------------------------FKEAVFQYALYEPGLLEPEGVSKVFFTCDS-H 154
             F                           +  +     +          K         
Sbjct: 120 ANFSDLLVDLNKKLTFKKAVSFAAGSDEIMKIKYVPDFKDLLKKPSFEAMKFVAFHPDGP 179

Query: 155 EQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGD 214
           +    + Q I       + V+ S+ T +E+      KG AL   AK  GY   + +A GD
Sbjct: 180 KVFNHIRQEIKKI--GDLIVTASSSTNIEINNIKAQKGIALMDYAKLQGYQPDEVMAIGD 237

Query: 215 GMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKL 263
            +ND  M+ MAG G  M +A   +K++     +  TN ++ V + +R  
Sbjct: 238 NLNDESMIRMAGIGVAMENAAPEIKEIAN--FITKTNNENGVAYAIRHF 284


>UniRef50_B9DIS6 Predicted hydrolases of the HAD superfamily n=61 Tax=Bacillales
           RepID=B9DIS6_STACT
          Length = 281

 Score =  250 bits (640), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 61/268 (22%), Positives = 112/268 (41%), Gaps = 8/268 (2%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++  DLDGTLL+    +SPY  + L+ L  +G   + ATGR         + L++ + ++
Sbjct: 5   LICLDLDGTLLNDKKEISPYTLKVLEKLKEQGHYIMIATGRPFRASKPYYEQLKLNTPIV 64

Query: 64  TSNGARVHDLD--GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
             NGA VH+     + +    LD D+A+ +   +             D  +++       
Sbjct: 65  NFNGAFVHNPTDPDSPVIHETLDPDLATSIIESLQKMQVKNIIAEVKDHVYIDNFDQHLF 124

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
             F     +    +      E  + +    D    +  ++Q ++  + + +         
Sbjct: 125 DGFSMGNPKIETGDIVNQLKEPPTSILIEADEV-MIPRVKQMLSRFYAESIEHRRWGAPF 183

Query: 182 --LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +E++  G+SK   +++V  +LG      IAFGD  ND EM+  A  G  M +    LK
Sbjct: 184 PVIEIVKRGISKARGIDSVKDELGVDRNHIIAFGDEDNDTEMIKYAKHGIAMENGLDELK 243

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY-LS 266
            +    EV  +N DD +  YL   + L+
Sbjct: 244 HIAN--EVTYSNNDDGIGRYLNDFFSLN 269


>UniRef50_UPI0001C423D6 hypothetical protein BpOF4_15910 n=1 Tax=Bacillus pseudofirmus OF4
           RepID=UPI0001C423D6
          Length = 284

 Score =  250 bits (640), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 62/287 (21%), Positives = 114/287 (39%), Gaps = 30/287 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A D+DGTLL  +  ++    + +K    RGI  V ATGR   +     D  ++   +
Sbjct: 2   KMIAIDMDGTLLDDERKVTVENVKAIKEAQKRGIEVVIATGRDDKEARIPLDEAKLTCPV 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP---- 118
           I+ NGA V   DG ++  ++LD +       +++ +  +   +Y +   F + +      
Sbjct: 62  ISVNGAEVQSADGKVLDVYSLDNETVKKASEILHRHE-VYFELYTNKGAFTDDYEKGIET 120

Query: 119 --------------------EEMRFFKEAVFQYALYEPGLLEPE-GVSKVFFTCDSHEQL 157
                                E R+   AV     Y+    +P     K+       ++ 
Sbjct: 121 VIDVLLSSGSTDSLDHMREIAEERYETGAVSHIENYQALFDDPTISFYKLLAFTKDDQKR 180

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
              +  +     D + +S S    LE+      KG A++  A  L   +++ +  GD  N
Sbjct: 181 TKAKHELEEM--DHLAISSSASDNLEITHCEAQKGRAVKRYAAGLDIPMEEVMVIGDNGN 238

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           D  M  +AG    MG+A + +K L    EV  TN +  V   +  + 
Sbjct: 239 DLSMFKVAGHAVAMGNAIEEVKSLA--QEVTDTNDNSGVAKAIYNIL 283


>UniRef50_Q2B1F0 Putative uncharacterized protein n=2 Tax=Bacillus
           RepID=Q2B1F0_9BACI
          Length = 298

 Score =  250 bits (640), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 69/285 (24%), Positives = 118/285 (41%), Gaps = 28/285 (9%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + +A D+DGTLL+    ++   ++ ++   A G+  V ATGR + +   + +   I +
Sbjct: 11  MVKCIAIDMDGTLLTATQQITEENRKAIQKAQAEGVEVVIATGRSYFEANFVLEEAGIHT 70

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP-- 118
            MI  NGA V  +D  +I ++ LD+  A    G+      +   VY +   +        
Sbjct: 71  PMICVNGAEVRSIDKEVIASNPLDKSTARTA-GMALLQNGVYFEVYTNKGTYTIDADKGV 129

Query: 119 ----------------------EEMRFFKEAVFQYALYEPGLLEPEG-VSKVFFTCDSHE 155
                                  E RF K  V +   Y+    + E  + K+       E
Sbjct: 130 SIIVDIFMSGNPEADVDEVMKAAEERFTKGLVQKVDSYDILFDDTEHQIYKLLAFSFDAE 189

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           +L   ++A+     + + +S S    LE+ +    KG ALEA  +K G  ++D +A GD 
Sbjct: 190 RLAAAKEALVPLEDEGLVISSSGEENLELTSKQAQKGVALEAFLEKSGTGIQDAMAIGDN 249

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
            ND  M    G+   MG+A + +K       V  TN +  V   +
Sbjct: 250 YNDLSMFKRVGRSVAMGNADEIIKAQCD--FVTLTNEESGVAKAI 292


>UniRef50_P42962 Uncharacterized protein ycsE n=9 Tax=Bacillus RepID=YCSE_BACSU
          Length = 249

 Score =  250 bits (640), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 59/264 (22%), Positives = 123/264 (46%), Gaps = 24/264 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A D+DGTLL+ +  +S   ++ ++    +G+  V +TGR  +   ++ ++L++ S+
Sbjct: 10  IKLIAIDMDGTLLNDEQLISDENRKAIREAEDKGVYVVISTGRTLMTCRELAESLKLSSF 69

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +IT+NG+ + D + NL+    L  D    ++  + +  +        ++ +         
Sbjct: 70  LITANGSEIWDSNFNLVERKLLHTDHIQMMWD-LRNKHNTNFWASTVNKVWRGEF----- 123

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
                         P  +      K  F  +  +    + + +       + ++ S+ T 
Sbjct: 124 --------------PENITDHEWLKFGFDIEDDDIRNEVLEELRK--NKELEITNSSPTN 167

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +EV A G++K  AL  V +KLG+++++ +A GD +ND  M+  AG G  MG+A   +K+ 
Sbjct: 168 IEVNALGINKAAALAKVTEKLGFTMENVMAMGDSLNDIAMIKEAGLGVAMGNAQDIVKET 227

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                +  TN +D V   +R   L
Sbjct: 228 AD--YITDTNIEDGVAKAIRHWVL 249


>UniRef50_C0R158 Putative hydrolase n=1 Tax=Brachyspira hyodysenteriae WA1
           RepID=C0R158_BRAHW
          Length = 267

 Score =  250 bits (639), Expect = 5e-65,   Method: Composition-based stats.
 Identities = 70/264 (26%), Positives = 124/264 (46%), Gaps = 5/264 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            Q++A+DLDGTLL+ +H +S Y K  +K  + +GI  + +TGR      +   +L+I + 
Sbjct: 4   IQLIATDLDGTLLNNNHQISEYNKNIIKAASKKGIKTILSTGRPTSAAIKFLYDLDIDTE 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEW-FMNRHRPEE 120
           +I+ NGA + D + N+I+  NL+  I  +L  +     +I    +  D W          
Sbjct: 64  LISFNGAMITDKNSNIIYQENLNPKIGIELINIAKKY-NIYHQGFLGDRWNIGFFDNKWT 122

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             +   A     +     +E    SK  F  ++H  L  + + +N  +G+ +  +FS   
Sbjct: 123 NFYISIAQIDNYIIGFDNIEDFSFSKFMFIGENH-ILKNIAEELNRTFGNSIYYAFSRPV 181

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LEV +   SK +AL+ +A K   +  + +AFGD  ND EML   G    + +A   +K 
Sbjct: 182 YLEVHSPNASKANALKYLADKYNINSDNIMAFGDNNNDLEMLEFVGISVAVENAEDIVK- 240

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
               L    +N ++ V  ++  + 
Sbjct: 241 -LKSLYTTKSNEENGVGIFINDML 263


>UniRef50_Q03PI8 Predicted hydrolase of the HAD superfamily n=14 Tax=Lactobacillus
           RepID=Q03PI8_LACBA
          Length = 271

 Score =  250 bits (639), Expect = 5e-65,   Method: Composition-based stats.
 Identities = 62/268 (23%), Positives = 98/268 (36%), Gaps = 6/268 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A DLD TLL+ D T+S      L+ L   GI  V  TGR    +    + L +  
Sbjct: 1   MIKMIALDLDETLLNTDKTISEENATALRQLHEAGIKIVLCTGRPINAIWHYLEQLGLTT 60

Query: 59  -KSYMITSNGAR-VHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y IT NGA  + +     +    L R+    L      N   +  +  D  + +   
Sbjct: 61  DDDYTITFNGALVIQNSTKEALAQSGLSRNDFEPLHAFAAANHYPMDVLDFDQVYPIADL 120

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
            P       +A  ++       L  +  SK          L  +   +        +V  
Sbjct: 121 TPSVYEQMLKAPMKFIPTAFADLPDQLFSK-AVMATDAAILDQVVAKLTPELTKLYHVVR 179

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LE +A  + K   L  +    G+   D +AFGD  ND  M+  AG G  M +   
Sbjct: 180 SQPKILEFLAADMDKAVGLGQLLTHFGWDFSDLMAFGDAENDLGMIKAAGDGVAMQNGQP 239

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
            +K        +  N    V  YL+ ++
Sbjct: 240 AVKAAANHQTPV-DNNHAGVAAYLQHVF 266


>UniRef50_A5FGB8 Cof-like hydrolase n=1 Tax=Flavobacterium johnsoniae UW101
           RepID=A5FGB8_FLAJ1
          Length = 281

 Score =  250 bits (639), Expect = 5e-65,   Method: Composition-based stats.
 Identities = 105/259 (40%), Positives = 154/259 (59%), Gaps = 1/259 (0%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +VV SDLDGTLL+P H +S Y K   + L  +    V ATGRHH+D   I + LE+  Y
Sbjct: 12  IKVVVSDLDGTLLNPQHKISDYTKSIFQELHNQNYLIVVATGRHHLDAMAIIETLEVPVY 71

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +++SNGAR+H  +   +FA NLD D+       V  +P I   +++++ W  N+      
Sbjct: 72  LVSSNGARIHSPNKEELFAFNLDSDVVKAALN-VEIDPAITVVLFKENVWQTNKWNERLN 130

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            F  E  ++  L +   LE  G  K+FF+CD HE+L+ L+  + A   + ++ +FS  TC
Sbjct: 131 SFQAELKYRPELVDYKKLEDFGAIKIFFSCDDHEKLVKLKDDVLANSSEHLHHAFSLPTC 190

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           LE M   + K  A+E V +K GY+L+  ++FGDG ND +MLS +GKG IMG+A   LK+ 
Sbjct: 191 LEFMDKSIDKAVAIEQVLEKEGYTLEQAVSFGDGFNDVQMLSASGKGLIMGNAPAVLKET 250

Query: 242 HPELEVIGTNADDAVPHYL 260
            P+LEVI TNA+D V  Y+
Sbjct: 251 LPDLEVIKTNAEDGVAKYI 269


>UniRef50_C7RDZ8 Cof-like hydrolase n=3 Tax=Anaerococcus RepID=C7RDZ8_ANAPD
          Length = 267

 Score =  249 bits (638), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 64/270 (23%), Positives = 114/270 (42%), Gaps = 8/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLE--- 57
           M ++VASD+D TL+  D  +    +  ++    +GI  + ATGR   ++  I        
Sbjct: 1   MIKLVASDIDETLVDNDKNVPERNRIAIQKAQEKGIIVMLATGRGTYELFDIPKQAGVIH 60

Query: 58  IKSYMITSNGARVHDLDGNLI-FAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y+I  NGA + ++    I  +  L  + A  +F     N      +Y  D  +    
Sbjct: 61  DDRYVICCNGAIIMNVKTKEIVHSMGLKYEYAKTIFDYAYANNQTCY-IYTLDHKYGLNL 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             +   + +E + +        ++ + + K          L  LE  I       V +++
Sbjct: 120 DRD--SYAEEQITELTDNNIDFIKDQIILKAILKNKDMNYLQGLEIDIAYLTNYDVEIAY 177

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S+   +E+ A GV+K  ALE V +  G  L + +A GD  ND  ML  AG    + +AH 
Sbjct: 178 SSDMFMEINAKGVNKARALEKVCEHYGIGLDEVLAIGDNYNDVAMLGEAGTSVAVANAHL 237

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           ++K+    +    TN + AV   + +  L+
Sbjct: 238 QVKESANFVAEA-TNEEGAVGEAIERFVLN 266


>UniRef50_Q034C6 Predicted hydrolase of the HAD superfamily n=8 Tax=Lactobacillus
           RepID=Q034C6_LACC3
          Length = 273

 Score =  249 bits (638), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 59/269 (21%), Positives = 105/269 (39%), Gaps = 10/269 (3%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M + +A D+D TLL+    +S   ++ L+ L+ +GI  +  +GR    +    D L +  
Sbjct: 1   MLKAIALDMDNTLLNSQKEISVTNQDVLRYLSRKGIRVILCSGRPFATLKPFLDQLHLTK 60

Query: 59  -KSYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFM-NR 115
                I  NG  V  + D  +I +  L +     ++ +V +      +V  +D+ +    
Sbjct: 61  NDDVCICFNGGLVRLVRDHTVIKSSTLTKSQIQPVYDLVKEK-GFHLDVVAEDQVYSLTE 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                          +       +  +            E +    +A  +  G  V V+
Sbjct: 120 FGKSSYESMIPKQMPFTDTTFAKVPAKLSIFKVVIAGDPEMVDAASEAAQSLEG--VTVT 177

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S  T LE+M   V+K + L+A         +   AFGD  ND +ML  AG G  MG+A 
Sbjct: 178 RSRRTLLEIMPPNVNKKNGLKAALNFYRIPREQLAAFGDEENDQDMLDYAGIGIAMGNAI 237

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
             +K +        +N +D V  +L   +
Sbjct: 238 PEIKKIADI--TTQSNDEDGVAKFLIDYF 264


>UniRef50_B6WB05 Putative uncharacterized protein n=1 Tax=Anaerococcus hydrogenalis
           DSM 7454 RepID=B6WB05_9FIRM
          Length = 268

 Score =  249 bits (638), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 63/270 (23%), Positives = 121/270 (44%), Gaps = 8/270 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A D+DGTL++  H ++   K TL      G   V A+GR    V  + + L+   
Sbjct: 1   MKKIIALDVDGTLVNSKHVITEKTKNTLLKCQKEGHILVIASGRDVEGVKDLAEELQFDK 60

Query: 61  Y---MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN-R 115
           Y   +   NG RV +   G ++F H    D ++++   V  N D+    ++D + + + +
Sbjct: 61  YNGLLSNYNGCRVTNFATGQVLFNHTFKIDQSNEIISFVK-NLDVEIFTFKDGKVYSDDK 119

Query: 116 HRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
           +    +   K     Y + +      + ++       S +++  +   +   + ++  V 
Sbjct: 120 NNKSLIDTTKRLKIGYLIDKNMRNGIDFLANNMIIGASKDKIDQVYPIVQKEFENKYTVV 179

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            +T   +E M  G SKG +L  +AK      ++ IAFGD  ND  M  +      MG+A 
Sbjct: 180 RTTENYVEFMPRGFSKGSSLLEIAKYYNIDKENIIAFGDEENDYSMFDIGAFSVAMGNAS 239

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +++K+      V  +N +D + +YL    L
Sbjct: 240 EKIKEKAD--FVTKSNDEDGIAYYLENYLL 267


>UniRef50_B7GIB3 Predicted hydrolase of the HAD superfamily n=3 Tax=Bacillales
           RepID=B7GIB3_ANOFW
          Length = 258

 Score =  249 bits (638), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 64/263 (24%), Positives = 104/263 (39%), Gaps = 10/263 (3%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++V  D+DGTLL  D  L     E +  L  +G+    ATGR       +R  L+I S  
Sbjct: 4   KIVFFDIDGTLLDHDKQLPESTYEAIHELKKQGVYVAIATGRAPFMFEALRKELDIPS-F 62

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           ++ NG  V   +G +I+   LDR     L  +  DN   +  +  D         P    
Sbjct: 63  VSFNGQYVV-FEGEVIYNQPLDRKQLRALKQMARDNDHPLIFMDADTMRASVPDHPYIHE 121

Query: 123 FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
                 F +  ++    E   + +    C   E+   ++           +         
Sbjct: 122 SMGSLKFTHPPHDETYDERNDIYQALLFCKPEEEQPYIQSF------PTFHFVRWHAVST 175

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +V+  G SK   ++ +  +LG   ++  AFGDG+ND EML   G G  MG+ H+  K + 
Sbjct: 176 DVLPYGGSKAEGIKKMMNELGIPRENVYAFGDGLNDTEMLRFVGTGVAMGNGHEEAKKVA 235

Query: 243 PELEVIGTNADDAVPHYLRKLYL 265
               +     +D +   LR L L
Sbjct: 236 D--FITKPVDEDGILFGLRHLGL 256


>UniRef50_P74365 Sll1524 protein n=1 Tax=Synechocystis sp. PCC 6803
           RepID=P74365_SYNY3
          Length = 279

 Score =  249 bits (638), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 113/272 (41%), Gaps = 10/272 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++V  D+DGT+    + ++P   +T+  + +RGI    ATGR      +    ++    
Sbjct: 3   IKLVVLDIDGTIAGVSNQINPSVVKTIHQVQSRGIQVALATGRMFSSALRFHQTIQSTLP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVND---NPDIITNVYRDDEWFMNRHR 117
           +I+ NGA       G ++    L   IA ++          P +  + Y +D+  +    
Sbjct: 63  LISYNGALTKHPHTGAVLREKPLPPAIALEILDHFERPELEPHLDIHCYYNDQLHVRHIT 122

Query: 118 PEEMRFFKEAVFQYALYEP--GLLEPEGVSKVFFTCDSHEQLLPLEQAINARW-GDRVNV 174
           PE   + + +            ++E    +K+     +   +  L   +  +  G  V++
Sbjct: 123 PETHVYMERSGAMAQASGDLRSIIELGSTTKMLAISRNAPLMAQLMAEMGQKLQGQAVHL 182

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKK-LGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGS 233
           + ST    EV     +KG AL+ +A+  LG   ++ +A GD  ND EML  AG G  MG+
Sbjct: 183 TQSTEIYFEVTHAEATKGLALQHLAEDVLGLDPQEVLAIGDNFNDVEMLKYAGVGVAMGN 242

Query: 234 AHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           A   ++ +     V      D V   L +  L
Sbjct: 243 APPEVQKVADW--VTADVEADGVSQALARFCL 272


>UniRef50_A1SZR3 Cof-like hydrolase n=2 Tax=Psychromonas RepID=A1SZR3_PSYIN
          Length = 263

 Score =  249 bits (638), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 94/264 (35%), Positives = 146/264 (55%), Gaps = 2/264 (0%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           MY++  SDLDGTLL PDH +S   +ET++     G  FV ATGRH+++   ++++L I  
Sbjct: 1   MYKIAISDLDGTLLGPDHRISVKTEETIQRWVQSGRKFVIATGRHYIEAKHLQESLNIPI 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           Y+ITSNGAR+H+ +G +I   NL  +IA ++   V  +  +  N++ D  W+ N    E 
Sbjct: 61  YLITSNGARIHNKEGKIIHQQNLPSNIAQEICDTVFSDA-VQINLFTDQNWYANYPLAEL 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
                +A F     +   L+     K+FF  +  E L P+   + AR+GD++N++FS   
Sbjct: 120 DGMGLDAGFNCIKADLSKLDKSNTIKIFFYAE-AELLQPVYDLLAARYGDKINLTFSLTK 178

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
           CLEVM    +KG A++ V K+    + D IAFGDGMND EML    K  +M +A   LK+
Sbjct: 179 CLEVMCANTNKGEAVKVVLKRKSLEISDAIAFGDGMNDLEMLLAVAKPIVMANAQYALKE 238

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
             P +E   ++ +  V   + +  
Sbjct: 239 ALPNVEKTLSSKEHGVAVIMERYL 262


>UniRef50_Q1WV35 Hydrolase, HAD superfamily n=2 Tax=Lactobacillus salivarius
           RepID=Q1WV35_LACS1
          Length = 273

 Score =  249 bits (637), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 67/270 (24%), Positives = 102/270 (37%), Gaps = 8/270 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS- 60
            +++A+D+DGTL+     LSP   E LK   A GI  V  TGR    V  +   L + + 
Sbjct: 4   IKMIATDIDGTLVDDAKNLSPKTIEVLKKARANGIYVVLCTGRPLSGVANLLTQLGLDND 63

Query: 61  --YMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             ++IT NGA+      G  IF H LD      L  +  +    +  +  D + F+    
Sbjct: 64  DNFVITHNGAQAVSAKSGKAIFKHLLDFSDFKRLDAISKELKVNMQTITTDSQLFVTSPD 123

Query: 118 PEEMRFFKEAVFQYAL-YEPGLLEPEGV-SKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                          L Y P    PE +        D  E +      +     D+ +  
Sbjct: 124 INYYSVLDTFYTHMQLRYRPVTEVPEDIEIAKIMWADYPENIDNALPNLPKDLLDKFDCI 183

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S     E M    +KG+A   + K LG    + +  GD  ND  M+   G    MG+A 
Sbjct: 184 RSEKWFFEFMNPLATKGNAAIELGKHLGIDASEILTAGDQNNDLSMIEKGGFSIAMGNAI 243

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +K+      V  TN +D +   + K   
Sbjct: 244 DTIKEKAD--YVTDTNNNDGLAKAIEKFVF 271


>UniRef50_Q3D5Y9 Hydrolase, haloacid dehalogenase-like family n=9 Tax=Streptococcus
           agalactiae RepID=Q3D5Y9_STRAG
          Length = 265

 Score =  248 bits (636), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 72/265 (27%), Positives = 131/265 (49%), Gaps = 5/265 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ SD+DGTL++ +  ++P  ++ +K + A+G  FV  + R    +  I + + I S
Sbjct: 1   MVRLIFSDIDGTLINSNFKVTPKTRQGIKQIVAQGATFVPISARMPEAITPIMEQIGIDS 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNP-DIITNVYRDDEWF-MNRHRP 118
           Y+I+ NGA + D+    I +H +D  +A  +   V+ +   I  NVYR  EW+  ++   
Sbjct: 61  YIISYNGALIQDMQQKTIASHTMDGQVALQVCSYVSKHYSKIAWNVYRYHEWYSCDKENE 120

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
              +  +    Q        LE +              +  LE  + A++   ++++ S 
Sbjct: 121 WVQKEEEIVGLQSKEMSLMELEKQDRIHKLLLMGEPSLMGELENTLKAQYP-HLSIAQSA 179

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              +E+MA G+ KG + + +A  L  SL D IAFGD  ND  +L + GKG +MG+A + L
Sbjct: 180 PYFIEIMAPGIEKGKSAKTLADYLDISLADSIAFGDNYNDLNLLEIVGKGFVMGNAPKDL 239

Query: 239 KDLHPELEVIGTNADDAVPHYLRKL 263
           ++      V   N +D + + L + 
Sbjct: 240 QER--IGNVTQDNDNDGIYYALVEY 262


>UniRef50_C0CY86 Putative uncharacterized protein n=3 Tax=Clostridium
           RepID=C0CY86_9CLOT
          Length = 265

 Score =  248 bits (636), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 60/265 (22%), Positives = 117/265 (44%), Gaps = 5/265 (1%)

Query: 1   MYQVVASDLDGTLL-SPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK 59
           M +++ SD+DGTL+      ++P   + +  L  +GI F  A+GR    V    + ++ K
Sbjct: 5   MIKLIVSDVDGTLVEDGSGGVNPELFDVILKLREKGIQFAIASGRPWASVEGAFEPVKKK 64

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            + I +NGA      G  +F + ++ ++  ++   V  +PD+       D  +M+     
Sbjct: 65  IFYIANNGAY-LGCHGRSLFVNPIEPELVREVIEAVRRHPDLSAIYAGQDGDYMDSENDA 123

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
             R+  E           +L  E            + +      I   + DR+ ++ +  
Sbjct: 124 LYRWMLEGYKFNIRRVKDVLALEDPCIKISIYKEQD-VEHAAADIREAFQDRMKITLAGE 182

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             ++ MA GV+KG A++ + + L    ++ +AFGD +ND EML  A     + +A + ++
Sbjct: 183 MWMDCMAQGVNKGQAVKRLQESLEIRPEETMAFGDQLNDIEMLQQAYYSFAVANAREEVR 242

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
            L        +N +D V   L++L 
Sbjct: 243 KLA--RFQADSNKNDGVLKVLKQLL 265


>UniRef50_A4XJ10 Cof-like hydrolase n=2 Tax=Clostridia RepID=A4XJ10_CALS8
          Length = 279

 Score =  248 bits (635), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 70/277 (25%), Positives = 119/277 (42%), Gaps = 16/277 (5%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-K 59
           MY+++A DLD TLL  +  +S   K  +KL   +G++ V  +GR    V      L +  
Sbjct: 1   MYKLLAIDLDMTLLDREKKISQKNKVAIKLAKQKGLHVVLCSGRILKGVMHFAKVLGLSD 60

Query: 60  SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
             ++  NGA V DL     ++   LD D + ++  +   N +I  + Y  D     R   
Sbjct: 61  EVVVACNGAIVRDLKTNKDVYYIGLDNDSSIEIAKICKAN-NIYYHYYYKDIMITQRLDY 119

Query: 119 EEMRFFKEAVF-----QYALYEPGLLEPEG-----VSKVFFTCDSHEQLLPLEQAINARW 168
               ++++        +  +     LE        ++K        E++  + + I    
Sbjct: 120 SSRFYYEKNKELPDDEKIEIIVDDSLETIKSCENLITKFVIIDKDIEKVDYVRKQIQENV 179

Query: 169 GDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKG 228
            + +  + S +  LE+M  GV+K +ALE V   L    K+ IA GD  ND EM+  AG G
Sbjct: 180 YN-IETTKSDVNILEIMKKGVNKRNALECVCSYLKIDKKEVIAIGDNENDLEMIGFAGLG 238

Query: 229 CIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             M +A   LK++     +  +  +D V   + K  L
Sbjct: 239 IAMENAIDSLKEIAD--YITDSYENDGVAKAIEKFVL 273


>UniRef50_C6PUS4 Cof-like hydrolase n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6PUS4_9CLOT
          Length = 276

 Score =  248 bits (635), Expect = 1e-64,   Method: Composition-based stats.
 Identities = 66/276 (23%), Positives = 123/276 (44%), Gaps = 14/276 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ASD+DGTLL+ D  +S Y    +   T+ G+ FV A+GR    +    + +     
Sbjct: 3   YKIIASDMDGTLLNDDKNISNYNLAMINKATSLGVKFVIASGRVPATLKFYEETIGKNQP 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEW---------- 111
           +I +NGA V D + N+I+++ + +     +  ++ ++ D   + Y  + +          
Sbjct: 63  IICANGAIVLDHNKNIIYSNPISKSNLIKIINILREDKDTYYHFYDGNVFCSEQFEYSAK 122

Query: 112 -FMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            F N +R  + ++  E        +  +     + K+    D  + L  L   I+    +
Sbjct: 123 KFYNFNRKVDQKYRMEIRLIKDAKDYIIRSNSNIDKIVVMDDDVKYLEYLRCKIDNL--N 180

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            +  + S +  LE+M  G SKG AL+ +AK     ++ CIA G+  ND  M+  AG G  
Sbjct: 181 EIETTKSEINNLEIMGIGSSKGTALKLLAKYYEIPIEQCIAIGNDENDISMIKAAGVGIS 240

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           M +    LK     +     N +  +   + K  L+
Sbjct: 241 MANGRNSLKQYANYITE-KNNNNGGIGEIIEKFILN 275


>UniRef50_C1QEL1 HAD-superfamily hydrolase, subfamily IIB n=3 Tax=Brachyspira
           RepID=C1QEL1_9SPIR
          Length = 266

 Score =  248 bits (635), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 65/264 (24%), Positives = 126/264 (47%), Gaps = 7/264 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLT-ARGINFVFATGRHHVDVGQIRDNLEIKS 60
            +++A+DLDGTLL+ +  +S Y ++ +K L     I+F+ ++GR    +      LE  +
Sbjct: 8   IKLIAADLDGTLLNSNKEISKYNQKIIKKLINEYNIDFILSSGRPFEGIKNYNKLLENNN 67

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             I  NGA + D +G +IF   ++ + +  +  +     D+  +VY + ++ +++     
Sbjct: 68  LSIIFNGASIADNNGKIIFQQTIEEESSKQIIELSKKY-DVCMHVYNNGKYIISKENFPI 126

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             + +       +      +     K+       + L  L++ I++   + V+  FS   
Sbjct: 127 KSYVQIEKTVNVIVGLENTDDYNFDKILILGQ-RDILEKLKKEIDSL--NCVHTCFSGDL 183

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            LE +    +KG+AL+ + +     +KD IAFGD  ND EM+  AG G  MG+A + +K 
Sbjct: 184 FLEAVNKASNKGNALKRICEIKKIDIKDTIAFGDNFNDIEMIKYAGIGVAMGNAEEIVKQ 243

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
                 +  +N +D V  +L  L+
Sbjct: 244 EA--YYITLSNEEDGVGKFLSDLF 265


>UniRef50_A6LS28 Cof-like hydrolase n=4 Tax=Bacteria RepID=A6LS28_CLOB8
          Length = 275

 Score =  248 bits (634), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 72/273 (26%), Positives = 121/273 (44%), Gaps = 11/273 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTAR-GINFVFATGRHHVDVGQIRDNLEIKS 60
           Y+++A D+D TLL+ +H +     + +K      G+ FV ATGR +  +      L++  
Sbjct: 3   YKLIACDMDETLLNDNHIICQRNIDLIKRAKKEYGVKFVPATGRGYSSIQNDLKILDLYD 62

Query: 61  ----YMITSNG-ARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I+ NG A   + D  L+    L  D   ++F     N D+  +VY  D+ ++  
Sbjct: 63  QAGEYIISFNGGALTENKDNKLLQFKGLRFDKMKEIFEYGL-NKDVCIHVYTKDKLYIYN 121

Query: 116 HRPEEMRFFKEAVFQYALYEP---GLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
               E    K    +  + +     LLE E ++K+ +   +   L+ +E  + +      
Sbjct: 122 LSQSEKERIKNQKLECTIMKENTVDLLEEEPIAKIIYQNINVPYLMGIEPDMRSITEGHC 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            VS+S+   +E  + GV KG  L  +AK L   +KD IA GD  ND  ML +AG     G
Sbjct: 182 AVSYSSNRYMEFNSLGVDKGSGLINLAKILDIDIKDTIAVGDNYNDMSMLKVAGLSVASG 241

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +A + +K           N +  V   + K  L
Sbjct: 242 NAVEDVKRACDYTTEA-DNNEGVVAELIEKFIL 273


>UniRef50_A0M3X3 Haloacid dehalogenase-like hydrolase n=2 Tax=Flavobacteriaceae
           RepID=A0M3X3_GRAFK
          Length = 269

 Score =  247 bits (633), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 60/272 (22%), Positives = 127/272 (46%), Gaps = 13/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           M++++ SD+DGTLL+ +  LS Y  ET++ L+   I F+  + R    +  ++  ++I+ 
Sbjct: 1   MFKIIFSDIDGTLLNAERDLSEYTIETIRKLSKADIPFILISSRMPAAMRHLQKKMDIEH 60

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
             +I+ NG  +  +DG ++ +  +  +I ++L    N++ ++  +++ +DEW++ R    
Sbjct: 61  LPIISYNGGLII-VDGKVVSSTEIPIEILTELHKF-NEHQNVHLSLFHNDEWYVPRDDFW 118

Query: 120 EMRFFKEAVFQYA------LYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVN 173
             R       Q        +      E +G  K+    +  E++  +   +   + D ++
Sbjct: 119 TQREINNTRVQPEFESNQNVINKWRKESKGAHKIMAMGE-EEKIDAIMTFLLQNFKDELH 177

Query: 174 VSFSTLTCLEVMAGGVSKGHALEAVAK-KLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           +  S  T +E+    +SK  A++ +        L   +AFGD  ND EM+   G G  +G
Sbjct: 178 LYRSKPTYIEIAPKAISKLTAVQHLLDNHFRIPLSQSMAFGDNYNDVEMIRGVGMGIAVG 237

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A   + ++     V     +D V   + +L 
Sbjct: 238 NAKPEVLEIA--HMVTTPGKEDGVAKSIMELL 267


>UniRef50_C3WB32 Hydrolase n=3 Tax=Fusobacterium RepID=C3WB32_FUSMR
          Length = 270

 Score =  247 bits (633), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 61/269 (22%), Positives = 119/269 (44%), Gaps = 7/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ +DLD TLL+ +  +S   KE +      GI FV A+GR    +  +   LE++ Y
Sbjct: 3   YKIIFTDLDDTLLNSEKKISQIDKEAIMKAQEAGIKFVLASGRPTFAMYDLAKELELEKY 62

Query: 62  ---MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              +++ NG+ + +   G  IF  +L ++    ++    +N       Y DDE       
Sbjct: 63  GSFILSFNGSIITNCKSGEHIFEESLTKEDLHLMYDFAKENS-CHILTYIDDEIISETES 121

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
                        + + +         +      +    L  +E+ +  ++GD+ +++ S
Sbjct: 122 EYIDVEVTLTKMPHKIVKNFKEAVNKPAVKCMILEEPSYLKEVEKKLKEKYGDKYSIAIS 181

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LEV   GV KG AL+ + + LG  +++ IA GD  ND  ML  AG    + +A++ 
Sbjct: 182 KPFFLEVTKLGVDKGVALKNLVETLGMKIEESIAVGDSYNDLPMLKAAGLAACVENANED 241

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +K +     +  +N +  + + +  L  +
Sbjct: 242 IKKVC--SFISKSNDEGGMAYLIENLIFN 268


>UniRef50_B1MWW3 Predicted hydrolase of the HAD superfamily n=3 Tax=Leuconostoc
           RepID=B1MWW3_LEUCK
          Length = 271

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 75/270 (27%), Positives = 112/270 (41%), Gaps = 9/270 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            ++V+ D+DGTLL+    ++P  K+ +K   A+ +  V  TGR    V  I   L I   
Sbjct: 4   IKIVSIDIDGTLLNDQREVTPEVKQAIKHALAQDVKIVITTGRPLPGVKGILAELGIAGD 63

Query: 59  KSYMITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y+IT NG  V   DG   +F   L       +   +    D    V   D  +   H+
Sbjct: 64  NQYVITYNGGLVQTADGKKTLFRQPLSVAEFKKINDFMVSK-DTYVQVETHDAAYTTHHK 122

Query: 118 PEEMRFFKEAVFQYALYE-PGLLEPEGVSKVFFTCDSHE-QLLPLEQAINARWGDRVNVS 175
                 F+ ++    L+      E E V  +    +  E +L  ++ A+       VNV 
Sbjct: 123 IHPWASFENSLVNLPLFVLDSEAELEKVEFIKAIANDEESKLDLVQAAVPDDISQNVNVI 182

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            ST   LE +    SKG+AL A+AKKL     + +A GD  ND  M+  AG G  MG+A 
Sbjct: 183 RSTANNLEFIDRQASKGNALLALAKKLAVKPSETMAIGDQANDYSMIEQAGIGVAMGNAI 242

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
             +K +        TN    V   +    L
Sbjct: 243 PDIKQIAD--FETATNNASGVAKAIEHFVL 270


>UniRef50_C5EF13 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C5EF13_9FIRM
          Length = 273

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 65/265 (24%), Positives = 115/265 (43%), Gaps = 8/265 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++ SD+DGTLL+  H +    ++ +  L   G+ FV  + R    +  I+  +  ++ 
Sbjct: 10  YKMIFSDIDGTLLNSGHQVPEPTRKKILELEKEGVPFVLVSARMPEGMTTIQAMIGNRAP 69

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVV-NDNPDIITNVYRDDEWFMNRHRPEE 120
           M+  +GA + D DGN +++  +D D+A  +  ++  + P+I  N Y    W ++      
Sbjct: 70  MVCYSGALIRDADGNTMYSCQMDLDLAVRIKDLIGKEFPEICCNTYGGSRWVVDDDSSPW 129

Query: 121 MRFFKE---AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
           +R  +E                   GV K        E +  LE+ +   + D ++++ S
Sbjct: 130 VRKEEEITGLKAMNGDIREVFTADRGVHKFLLMGQ-EEAVQGLEKRLKEHFPD-LSIASS 187

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
           +   LEVM G VSK   +  +    G  L + IAFGDG ND +ML        M +A   
Sbjct: 188 SPVYLEVMDGRVSKSRGVGFLCSHYGVGLDEVIAFGDGCNDMDMLRAVKNSYAMANAPLG 247

Query: 238 LKDLHPELEVIGTNADDAVPHYLRK 262
           ++       V   N        L +
Sbjct: 248 VRRSAAH--VTLDNDHQGFLAALEE 270


>UniRef50_UPI00018506A2 hypothetical protein Bcoam_01805 n=1 Tax=Bacillus coahuilensis m4-4
           RepID=UPI00018506A2
          Length = 289

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 67/290 (23%), Positives = 117/290 (40%), Gaps = 30/290 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M + +A+D+DGTLL+ +  +S   K  ++    +G+  V ATGR + +   +     +  
Sbjct: 1   MVKCIATDMDGTLLNHEQRISERNKLAIETAIQQGVKVVVATGRSYPEAATVLKEANLSL 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH---- 116
            +I  NGA + +  G ++++  + ++ AS +   +    DI   +Y +   F   +    
Sbjct: 61  PIICVNGAEIRNTAGEVVYSKGMKKERASFIAKELKKR-DIYFEIYTNKGSFSENYQLGV 119

Query: 117 ----------RPEEMRFFKEAVF----------QYALYEPGLLEPE-GVSKVFFTCDSHE 155
                      PE                    + + YE      E  V K        E
Sbjct: 120 DVIVDIFHTANPEIPEELIRKRAVERLEVGVFEEISDYETIFSSSEYDVYKFLVFSKQKE 179

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
            L    + +     + + +S S    LE+ +    KG AL     + G SL+D +A GD 
Sbjct: 180 VLKEAYEVLVEI--EDIAISSSGEENLEINSSDAQKGIALSHFVAEQGISLEDTLALGDN 237

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           +ND  MLS+ G    MG+AH+ +  L        TN +D V   +  + L
Sbjct: 238 LNDVSMLSVVGYPVAMGNAHKDVLALC--EYTTLTNREDGVGRAIESIVL 285


>UniRef50_A0R0M1 Cof protein n=3 Tax=Bacteria RepID=A0R0M1_MYCS2
          Length = 270

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 57/265 (21%), Positives = 107/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++ +D+DGTL++ D  L+      +  L   GI F   +GR    + ++ + L + + 
Sbjct: 8   IRLLLADVDGTLVTHDKVLTHRTLAAVAKLREAGILFAVTSGRPPRGMSKLIEPLGLTTP 67

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR-HRPEE 120
           +   NG      D ++I    +  D+ + +   + D   +   VYR  +W +   H P  
Sbjct: 68  LAAFNGGLFVRPDLSVIERRMISDDVTAAVIEQL-DTDGLTVWVYRGADWLVPDPHGPHV 126

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
            R  +   F     E       GVSK+    D H+ +      +  R+ D V+ + S   
Sbjct: 127 AREARTVGFGPTPIESYPPISRGVSKIVGVSDDHDAVRKAAARLRERFADHVSAATSQPY 186

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            ++V     +KG  +  ++     + +     GD  ND  M   +G    MG+A   ++ 
Sbjct: 187 YVDVTHPDANKGAVVSFLSAAYDIATESIATIGDMANDVAMFRKSGLSIAMGNAGDEVRR 246

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 V  +NADD     + +  L
Sbjct: 247 AA--RCVTASNADDGFADAVERFVL 269


>UniRef50_C9LXL4 HAD hydrolase, IIB family n=1 Tax=Selenomonas sputigena ATCC 35185
           RepID=C9LXL4_9FIRM
          Length = 265

 Score =  247 bits (632), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 65/267 (24%), Positives = 116/267 (43%), Gaps = 7/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  DLDGTLL+ +  +S Y+K+ L+    +G+    ATGR  +        +   + 
Sbjct: 3   IRLIVMDLDGTLLTSEKMVSDYSKDVLRRAMEKGVAVTLATGRMLLSASYFGRIIGANAP 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           +I+ NGA V  LD    +F      +  ++L     +N       Y  D+ +    RPE 
Sbjct: 63  IISCNGALVQALDATEPLFLRAFSPETVAELLTFAREN-GWYAQWYIGDDIYAEDFRPEY 121

Query: 121 MRFFK--EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
              ++  +    + + E      EGV++V    D    +  +  +I  R+  RV+   S 
Sbjct: 122 FTAYRTVQGFAVHEVGEDFSPYVEGVAQV-VVRDLAGGVGAIAASIRERFAGRVDPQQSK 180

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              L+++  GVSK   +EA+ +  G    + +A GD  ND  ML +AG   +  +  +  
Sbjct: 181 GYTLDLVPTGVSKATGIEAILRATGIRADEVMACGDSDNDLSMLRLAGTSVVTANGQEEA 240

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLYL 265
           K L     +     +D V   + +L L
Sbjct: 241 KALA--TYLAPGCDEDGVARAIEELVL 265


>UniRef50_C9KL53 HAD hydrolase, IIB family n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KL53_9FIRM
          Length = 267

 Score =  247 bits (631), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 58/266 (21%), Positives = 110/266 (41%), Gaps = 6/266 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ SD+DGTLL     +     E +  L  RG+ F  A+GR +  +       + + 
Sbjct: 1   MIKIIFSDMDGTLLDEHGNVPEGFDEIIAELEKRGVMFAPASGRQYYSLEDSFMKYKDRF 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH--RP 118
             +  NG  V    G  IF   +++ +A  +        ++ +        ++ +H    
Sbjct: 61  LFLAENGTVVM-YKGEKIFTCPMNKQLAQQVLKAAEPLENVYSVFCGTKNGYVLKHQYTE 119

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           E +    +     A     +  P+   KV F   +      +   +   +   + V  ++
Sbjct: 120 EFLAELHKYYTHSAPIPSFIDVPDEPVKVSFFDPTGHAEETIYPTMRQ-FEHCLQVVLAS 178

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              +++M  G++KG A++ V K+ G   ++C AFGD MNDAEM+        M +A+  +
Sbjct: 179 DYWVDIMNPGINKGVAVQEVQKRFGIRPEECAAFGDYMNDAEMMQSVYYSFAMANAYPEI 238

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           K L        +N D  V   + +L 
Sbjct: 239 KKLA--RFQTESNVDHGVLRGIERLI 262


>UniRef50_Q03GV9 Predicted hydrolase of the HAD superfamily n=2 Tax=Lactobacillaceae
           RepID=Q03GV9_PEDPA
          Length = 290

 Score =  247 bits (631), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 63/286 (22%), Positives = 114/286 (39%), Gaps = 31/286 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M  ++ASD+DGTLL+ +  +S    + +K   A G++F  ATGR + +   + +   +  
Sbjct: 1   MISIIASDMDGTLLNEEMQISSANADAIKKAQAAGVHFAVATGREYREAKPLLEAYGLSV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            +IT NGA V D+DG  +    + +  A  +   + +   +   +  +     N      
Sbjct: 61  PLITLNGAAVFDVDGKALDMVPITKPSAVLIMHQL-EKAGLYYEITTNQGVVSNSRTRRI 119

Query: 121 MR-------------------------FFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHE 155
                                            +              V K+    ++ +
Sbjct: 120 QTVAHLLETVNPDTPFKLAVAMSSARVELMNIRYVDDYQVLIDDPKIQVLKLVAFGENGQ 179

Query: 156 Q-LLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGD 214
           + L P+ +A++A+    V +S S    +E+      KG A++  A +L   +   +  GD
Sbjct: 180 KGLQPVREALHAKV--DVAISSSFENNIEINNPRAQKGIAVQHFADELNVPMSQVMTIGD 237

Query: 215 GMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
            MNDA ML +AG    MG+A   +K L   L V   N ++ V   +
Sbjct: 238 NMNDASMLKIAGVSYAMGNAIPEIKKLANHLTVT--NNENGVAKAI 281


>UniRef50_C3RM99 Hydrolase n=3 Tax=Bacteria RepID=C3RM99_9MOLU
          Length = 276

 Score =  247 bits (631), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 68/275 (24%), Positives = 117/275 (42%), Gaps = 13/275 (4%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTAR-GINFVFATGRHHVDVGQIRDNLEIKS 60
           Y+++A DLD TLL+ +H +       +K      G+ FV ATGR  + +      L++  
Sbjct: 3   YKLIACDLDETLLNDEHLVGAKNVAAIKRAREEYGVKFVPATGRGFMQIQPELKELQLYD 62

Query: 61  ----YMITSNG-ARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNR 115
               Y+I+ NG A   + +  +I    L+     ++F     N D+  +VY  D  ++  
Sbjct: 63  LEGEYVISFNGGALTENKNNRIIEFKGLEFSKMKEIFE-AGLNFDVCIHVYTPDNLYVFN 121

Query: 116 HRPEEMRFFKEAVFQ---YALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
               E +  K    +     +     L+   +SK+ +       L+ LE+ +        
Sbjct: 122 LSESERQRIKNQKLEAVYPEVNSVDFLKDTPISKILYQNVDVPYLMSLEEGLKPITDGHC 181

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
            VS+S+   +E  A GV KG  L  +A KLG ++++ IA GD  ND  ML +AG      
Sbjct: 182 AVSYSSNRYMEFNALGVDKGQGLIDLANKLGIAIEETIAVGDNYNDMAMLKVAGLSVAAN 241

Query: 233 SAHQRLKDLHPELEVIGTNADDA-VPHYLRKLYLS 266
           +A   +K           N ++  V   + K   +
Sbjct: 242 NAVDDVKAACD--YTTNANNNEGVVAELIEKFIFN 274


>UniRef50_Q67P94 Haloacid dehalogenase-like hydrolase n=1 Tax=Symbiobacterium
           thermophilum RepID=Q67P94_SYMTH
          Length = 284

 Score =  247 bits (631), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 70/283 (24%), Positives = 109/283 (38%), Gaps = 27/283 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A D+DGTL    H +SP     L +   RG   V ATGR      ++   +     
Sbjct: 3   YRLIALDVDGTLFCGRHRVSPRTLAALTVARRRGAITVIATGRTPHSALRVSAEIGG-GP 61

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           +I  NGA + D +G LI   ++  +    +  +     D++ + Y  +   +++     +
Sbjct: 62  VICCNGAGLLDEEGRLIHHRSIPTEPLLRVLKLGRQ-ADLLVHGYTPEGVVLDQPMAHLI 120

Query: 122 RFF----------------------KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLP 159
           R +                       +      L +                    +L  
Sbjct: 121 RAYAWLRAGGAALQSAVGVARLWGANQTRLVPRLTQWAASPHRPPVLKLTLFGDPARLPD 180

Query: 160 LEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDA 219
           +  AI       V V+ S    LEV A GVSKG  L A+ ++LG   +  IAFGD  ND 
Sbjct: 181 VADAIRREVPG-VEVTSSGPDNLEVTAAGVSKGSGLAALGERLGIPPEATIAFGDSDNDL 239

Query: 220 EMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRK 262
            ML  AG G  MG+A   +K       V    A+D V   L +
Sbjct: 240 TMLRYAGLGVAMGNAPPHVKAAADR--VAPPCAEDGVACVLEE 280


>UniRef50_Q5HRI8 Hydrolase, haloacid dehalogenase-like family n=67
           Tax=Staphylococcaceae RepID=Q5HRI8_STAEQ
          Length = 292

 Score =  247 bits (631), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 70/289 (24%), Positives = 114/289 (39%), Gaps = 30/289 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A+D+DGTLL+  H ++   +E +K   A GI  V ATGR   +        ++K 
Sbjct: 1   MIKLIATDMDGTLLNAGHEITTMNQEAIKFAQANGITVVIATGRAFYEAQTPVAETDLKV 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             I  NGA V D   N++   +L+ D+   +      N  I   +Y +   +    + + 
Sbjct: 61  PYICLNGAEVRDESFNIMSTSHLNHDLVHKI-TTALKNNHIYYQIYTNRGIYTEDPKRDL 119

Query: 121 MRFFKEA-------------------------VFQYALYEPGLLEPEGVSKVFFTCDSHE 155
             +   A                                    +  E + KV        
Sbjct: 120 AIYIDIAERAGQKADVDKIRNNIQKRIDNGTLKVVDNYDSIEDIPGELIMKVLAFDADLS 179

Query: 156 QLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDG 215
           ++  + QA+ +     + VS S+   LE+      KG AL A+A +LG  L D IA GD 
Sbjct: 180 KIDQVGQALAS--SPNLAVSSSSRGNLEITHSNAQKGIALSAIAHQLGIDLTDVIAIGDN 237

Query: 216 MNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +ND  ML   G    M +A   +K +     V  TN +  V   + K+ 
Sbjct: 238 LNDISMLERVGYPVAMNNATDEVKHIAK--YVTDTNENSGVGKAIMKIL 284


>UniRef50_Q7NXV0 Putative uncharacterized protein n=1 Tax=Chromobacterium violaceum
           RepID=Q7NXV0_CHRVO
          Length = 269

 Score =  247 bits (631), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 96/265 (36%), Positives = 136/265 (51%), Gaps = 11/265 (4%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIR-DNLEIKSY 61
           +++ SDLDGTLL  D  L+   +  L+   ARG+    ATGRH   V ++   +L     
Sbjct: 12  RLIVSDLDGTLLDKDARLADETRAALQAAVARGVALAVATGRHERQVRKLWPRDLP-PVP 70

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLF--GVVNDNPDIITNVYRDDEWFMNRHRPE 119
           +I++NGAR+H  DG L+    L   + + L    ++ +       VYRDD       R E
Sbjct: 71  VISANGARIHLADGTLLHQSRLSPALLARLLRPELIRETE---LGVYRDDCIMAYHSRRE 127

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
              +  E      + +    + E VSKV F C + EQL  +E  I    GD V++++S +
Sbjct: 128 YSHYTGEVT---EIEDLAGFKAEDVSKVIF-CGTPEQLKAVEADIARELGDEVSMTYSHI 183

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             LEVMA GV KG AL  +   L  + +DC AFGD +NDAEML++AG   +MG+AH  LK
Sbjct: 184 CYLEVMAPGVHKGSALRRLLDHLDIAAEDCAAFGDNLNDAEMLALAGLPHVMGNAHPELK 243

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
              P   VIG +    V   LR L 
Sbjct: 244 RRLPGAPVIGDHDQAGVARQLRALL 268


>UniRef50_UPI0001788F0C Cof-like hydrolase n=1 Tax=Geobacillus sp. Y412MC10
           RepID=UPI0001788F0C
          Length = 254

 Score =  246 bits (630), Expect = 5e-64,   Method: Composition-based stats.
 Identities = 64/264 (24%), Positives = 114/264 (43%), Gaps = 23/264 (8%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A DLDGTLL+ +  ++   K+ L+    +G+  +F+TGR         D L + S 
Sbjct: 11  YKLIALDLDGTLLTDEKHITDETKKWLQYAVDQGVKVMFSTGRGLQTAKGFWDELGLDSP 70

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           M+  NGA V +  G L     L RD   D+  +                           
Sbjct: 71  MVLLNGAEVWEGPGRLKKRVFLPRDAVRDMHAIAAKRG------------------EWYW 112

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTC 181
            +  E++     + P + E     K     +   +L  +++ + +     + V+ S  T 
Sbjct: 113 GYSVESLTGDKDWTPEMFE-RDWMKFGIGSNDQRKLAEIKEELLSW--GTLEVTHSAPTN 169

Query: 182 LEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDL 241
           +E+   G++K   +  V + LG+S+ D IA GD  NDA++L  AG G  M +  + +K +
Sbjct: 170 MEISVKGITKESGVREVCQTLGFSMSDVIAMGDSDNDAKLLKAAGLGVAMANGEEHIKSI 229

Query: 242 HPELEVIGTNADDAVPHYLRKLYL 265
                +  TN ++ V   +RK   
Sbjct: 230 AD--VITATNNENGVAQAIRKYVF 251


>UniRef50_B0TIL9 Cof-like hydrolase n=1 Tax=Heliobacterium modesticaldum Ice1
           RepID=B0TIL9_HELMI
          Length = 275

 Score =  246 bits (630), Expect = 5e-64,   Method: Composition-based stats.
 Identities = 62/269 (23%), Positives = 102/269 (37%), Gaps = 8/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLDGTLL     +       +  L  +G+ F  ATGR +         LE+++ 
Sbjct: 8   IRLVAMDLDGTLLDEKRRIPEPVARRIAELRGKGVIFTVATGRIYPSALPYAKQLELEAP 67

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVN-DNPDIITNVYRDDEWFMNRHRPE 119
           MIT NGA +    DG +I    ++   A  +   +   N D +   +  DE + +     
Sbjct: 68  MITCNGAMIRHPADGRIICHRTVEAKQALAVLQFLKAKNSDALRYSFHGDEVYTDTPHEY 127

Query: 120 EMRFFKEAVFQYALYEPGL----LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
              + +     +   +        EPE    +            L Q I A     V ++
Sbjct: 128 TTSYERGLGLSFTFVDDLTAHLAKEPERHPTMLVLMTDPAVTPALTQDILAHLNGTVTIT 187

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S    +E++    SKG AL  +A        + +A GD  ND  M+  AG+G  + +A 
Sbjct: 188 NSHDYFIEILHPEASKGAALAQLAASFSIDRSEVLAIGDNRNDLTMIHWAGQGVFVANAP 247

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           + L        V   +    V   L   +
Sbjct: 248 EVLHQAAD--YVTSASNSMGVLEALNYFF 274


>UniRef50_C2HD37 HAD superfamily hydrolase n=12 Tax=Enterococcus faecium
           RepID=C2HD37_ENTFC
          Length = 289

 Score =  246 bits (630), Expect = 5e-64,   Method: Composition-based stats.
 Identities = 70/286 (24%), Positives = 118/286 (41%), Gaps = 31/286 (10%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASD+DGTLL    ++SP   E ++     G+ F+ ATGR++ +     D + I  
Sbjct: 1   MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGRNYQEARAALDEVGIDC 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
            MIT NGA+V D +GN +F  ++  + A+ +  +++ N  I   V  +D  +        
Sbjct: 61  AMITLNGAQVFDKEGNSLFTVSIPNNQATSVLDILDAN-GIYYEVATNDGLYSENQAKRI 119

Query: 121 MRFFK-------------------------EAVFQYALYEPGLLEPEGVSKVFFTCDS-H 154
             F                              +  ++      +   V K+        
Sbjct: 120 ESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRTILEEKNLEVLKIICFHTEGP 179

Query: 155 EQLLPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGD 214
             L P+ + I+      + V+ S    +EV      KG A+  VA + G SL++ +  GD
Sbjct: 180 AVLGPVGKQIS--LLGDLAVTSSGQNNIEVNHKNAQKGIAVAHVAHERGISLEEVMTIGD 237

Query: 215 GMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
             ND  ML +AG    MG+A   +KD         TN +  V   +
Sbjct: 238 NFNDVSMLQVAGVSFAMGNAEIEVKDYAK--YTTDTNLESGVGKAI 281


>UniRef50_C7H2Z8 Cof family protein n=2 Tax=Faecalibacterium prausnitzii
           RepID=C7H2Z8_9FIRM
          Length = 273

 Score =  246 bits (629), Expect = 6e-64,   Method: Composition-based stats.
 Identities = 58/271 (21%), Positives = 115/271 (42%), Gaps = 9/271 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            +V+A DLDGTL + +  ++P  +  L    A+G+  V A+GR    +  +   L +   
Sbjct: 6   IRVLALDLDGTLTNDEKIVTPRTRAALDAAAAQGVTIVLASGRPTAGILPLAKELGLDKK 65

Query: 60  -SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              ++  NG ++ D   G  ++   L  +   +L        D+    Y  +     R +
Sbjct: 66  GGCVLAYNGGKIVDCVTGEALYQVQLGAEFVPELCEFAARQ-DVAILTYNSEGIVCERDQ 124

Query: 118 P--EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
                   F   +    + +        + K+  T     +   +  A   ++  R+++ 
Sbjct: 125 DVWANKECFTTKLPMLHVDDLASYVDYPICKMLITL-DPARRDAVCAAGKEQFAGRIDLY 183

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            S+   +E +  GV+K  +L A+ +++G + ++ +A GDG+ND  M+S AG G  M +A 
Sbjct: 184 PSSPFFIEAVPLGVAKDRSLAALLERMGLTRENLMACGDGLNDRSMISYAGVGVAMQNAE 243

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
             +K +   +     N  D V   + K  L+
Sbjct: 244 DAVKAVADYVT-AADNNHDGVAEAIEKFILN 273


>UniRef50_B0MA46 Putative uncharacterized protein n=1 Tax=Anaerostipes caccae DSM
           14662 RepID=B0MA46_9FIRM
          Length = 277

 Score =  246 bits (629), Expect = 6e-64,   Method: Composition-based stats.
 Identities = 64/277 (23%), Positives = 111/277 (40%), Gaps = 17/277 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A D+DGTLL+    ++ +  E L+    RGI  V ATGR    + +    L+   Y
Sbjct: 6   IKLIAMDMDGTLLTSSKEITEHTIEVLEAAMDRGIQIVPATGRSVNGLPKKLTALKRMRY 65

Query: 62  MITSNGARVHDLDGNL-IFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR--- 117
            I SNGARV+DL     I+ +  + D    L   V        ++ +D E +  +     
Sbjct: 66  CILSNGARVYDLHKKKSIYKNQFETDQVLKLLEDVRPY-HAFRSIAKDGEVYCYKEELDR 124

Query: 118 -------PEEMRFFKEAVFQYALYEPGLLEPEGVS-KVFFTCDSHEQLLPLEQAINARWG 169
                           +       +  +++  G S K+    +  E+     + +     
Sbjct: 125 LGSFHLGEYSEEMIHASRTPVEDLKDYIIQEGGTSEKMTLFFEDQEERAKARKELTE--S 182

Query: 170 DRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
               V  S    LE+     +KG AL  + + L    ++ +A GD  ND EM+  AG G 
Sbjct: 183 GLYTVVASLKNNLEISLDSCNKGDALAHLMEHLDLKKENVMACGDAENDYEMILAAGIGV 242

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +M +    +K +     +   +  D V   + KL L+
Sbjct: 243 VMENGSDDMKAIAD--YITDDHNRDGVAKAIEKLVLN 277


>UniRef50_Q04G35 Predicted hydrolase of the HAD superfamily n=2 Tax=Oenococcus oeni
           RepID=Q04G35_OENOB
          Length = 267

 Score =  246 bits (629), Expect = 6e-64,   Method: Composition-based stats.
 Identities = 70/267 (26%), Positives = 116/267 (43%), Gaps = 8/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
            +++A DLD TLL+ +  +S   +E LKLL  +G+  V  TGR    +    D LE+K  
Sbjct: 3   IKLIALDLDNTLLNANSEISSRNREVLKLLHNKGLKVVLTTGRPIKGILPFIDQLELKQP 62

Query: 60  -SYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y I  NG  + + L   +IF+  L ++    +  + N     +  V  D  + +   R
Sbjct: 63  EDYSINFNGGVIQNNLSKKIIFSKFLTKEDIVPINDLANQMRFPLDGVAIDRAYSIIDIR 122

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
               + F   +  +       L  +     F +    EQ+  +++   A       +  S
Sbjct: 123 KSGYQSFIGKLMDFTDLSFHDLPADEHYYKFISQTDPEQVAKIQE--KAADYPTFTIVKS 180

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LE +  GV+K   L  + K  G++  + +AFGD  ND  M+  AG G  MG+A + 
Sbjct: 181 RPNLLEFLPKGVNKSFGLGQLIKHFGWTFDNVMAFGDEENDLPMIKSAGIGVAMGNAIKE 240

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLY 264
           +K+      V   N +D V  YL K +
Sbjct: 241 VKEAAQA--VTKLNTEDGVAAYLVKYF 265


>UniRef50_D1PP54 HAD hydrolase, IIB family n=1 Tax=Subdoligranulum variabile DSM
           15176 RepID=D1PP54_9FIRM
          Length = 274

 Score =  245 bits (628), Expect = 9e-64,   Method: Composition-based stats.
 Identities = 73/275 (26%), Positives = 121/275 (44%), Gaps = 15/275 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            ++VA DLDGT+ + +  +SP   + ++   A+G++ + ATGR    V +    +    Y
Sbjct: 4   IRLVALDLDGTVFNDEKQISPRTLDAIRAALAKGVDVLPATGRTVTGVPRQFAEIPGVRY 63

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN------ 114
            +TSNGA V DL  G  +     D  +A   F VV     +  +V+ + E +        
Sbjct: 64  ALTSNGASVVDLQTGEKLVCLPFDAALAERAFDVVRPFGGM-LSVFINGESYTAASTSGD 122

Query: 115 --RHRPEEMRFF--KEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
                PE +R +          ++      P  + K      +  Q     QA+ A    
Sbjct: 123 GLEMVPENLREYFRTTRNVVPDMHRMMEEHPHEIEKFSILYPTEAQRDAAWQAVAAACP- 181

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
            + ++ S    +E+ A GVSKG  L A+AK+LG + +  +A GD  ND  M+ +AG G  
Sbjct: 182 TLEITSSIERNMELNAPGVSKGPGLMALAKRLGLAREQVMAVGDSGNDRTMVELAGLGVA 241

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           MG+A + ++       +   N  D V   + K  L
Sbjct: 242 MGNATEEIRQAAD--VITADNNHDGVAEAIEKYVL 274


>UniRef50_Q5FQA0 Putative hydrolase of the HAD superfamily n=1 Tax=Gluconobacter
           oxydans RepID=Q5FQA0_GLUOX
          Length = 266

 Score =  245 bits (628), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 65/263 (24%), Positives = 105/263 (39%), Gaps = 4/263 (1%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           +V SD+DGTLL+PD T++P     +++L  RGI    A+ R    +    + L +     
Sbjct: 1   MVVSDMDGTLLTPDKTIAPSTLAMVRVLQERGIPLCLASARPPAAMVPYIEQLGLTGQNA 60

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRF 123
             NG  +   DG    +  L  D+ S +  +++ +  I T   R   W +       ++ 
Sbjct: 61  GFNGGIIFKPDGTTSVSRVLSPDVLSIVHDMLHLH-GIETWFLRQSYWMVQDAYTPFVQH 119

Query: 124 FK-EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCL 182
            +               E EG+ KV         L  +E  + A      +V  S+   L
Sbjct: 120 EQGITGLTPHQVPDLRKEFEGIGKVMGVSSDTSLLQDVETELGAMLQGDASVRRSSDILL 179

Query: 183 EVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLH 242
           +V     +KG A+  +A  LG +  +    GD  ND  M S+AG G  MG A   +K   
Sbjct: 180 DVTPALANKGEAVRELALALGIAPHEVACLGDAHNDLPMFSVAGLGIAMGQAEDDVKAAA 239

Query: 243 PELEVIGTNADDAVPHYLRKLYL 265
               +  TN  D     + +  L
Sbjct: 240 --QVLTDTNERDGWAKAVERYIL 260


>UniRef50_A7VVP1 Putative uncharacterized protein n=1 Tax=Clostridium leptum DSM 753
           RepID=A7VVP1_9CLOT
          Length = 304

 Score =  245 bits (627), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 65/266 (24%), Positives = 114/266 (42%), Gaps = 5/266 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++ASDLDGTLL+    L       +  L   G+ F+ A+GR +  + +       + 
Sbjct: 39  MIRLIASDLDGTLLNSQRQLPKDFFSVIDRLNQLGVLFIAASGRSYPTLRRDFAPHSDEL 98

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN-RHRPE 119
             I+ NGAR+ +  G ++    +   + S +       P++   +  D   + N +  P 
Sbjct: 99  CFISDNGARIAE-HGKILQKDPIPPQVVSQVLETCASLPEVKPVLTSDRGTYANTKGEPW 157

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
                      Y   +      E   K+   CD    +    + +     D  ++  S  
Sbjct: 158 FHDCILAYFDNYQQVDDLSSVHEDFYKISL-CDRAGAVKNSFRLMPQSLRDSADLQVSGF 216

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             L+VM  GV KG AL+A  K+ G S ++ + FGD  ND++ML  A    +M +A++ +K
Sbjct: 217 IWLDVMKKGVDKGKALQAFQKRYGISKEETMVFGDFYNDSQMLLQAKYSFVMENANEDMK 276

Query: 240 DLHPELEVIGTNADDAVPHYLRKLYL 265
                  +  +N DD V   ++K  L
Sbjct: 277 PFGN--FIAPSNDDDGVMRMIKKYVL 300


>UniRef50_UPI0001C34D0C Cof-like hydrolase n=2 Tax=Clostridium RepID=UPI0001C34D0C
          Length = 275

 Score =  245 bits (627), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 70/278 (25%), Positives = 117/278 (42%), Gaps = 19/278 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A DLDGTLL+ D  LS   K  L+    RGI  V  TGR    + +    L+   Y
Sbjct: 3   IRLIALDLDGTLLTSDKRLSERNKRALEECIRRGIYIVPCTGRTFEGIPKPVRMLDGIKY 62

Query: 62  MITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRD----------DE 110
            I +NGA + D + G ++    L  + A  +   + D   ++ + Y +          D 
Sbjct: 63  TILTNGACIQDAETGEILERRGLFWEKAMQVIDRIEDFT-LMYDCYIEGRGKADRRFLDT 121

Query: 111 WFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGV---SKVFFTCDSHEQLLPLEQAINAR 167
                 RPE  R  +E        +  L + + +     ++F     E    + + +   
Sbjct: 122 LEYYEIRPEICRLIRETRDPLPSLKDYLAKKQPLLDKMNIYFKGCDRETKQRVRRELAEI 181

Query: 168 WGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGK 227
            G  + V+ S    LE+   G +KG A+  +A +L   +   +AFGDG ND  M+ +AG 
Sbjct: 182 EG--LVVTSSMPNNLEINGEGATKGDAIRLLADRLKIPVSQTMAFGDGENDRSMMELAGV 239

Query: 228 GCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
           G  M +     K+      +  +N  D V   + +L L
Sbjct: 240 GVAMENGSPLAKECA--SYIAPSNDADGVAEIIERLVL 275


>UniRef50_A6TMX9 Cof-like hydrolase n=1 Tax=Alkaliphilus metalliredigens QYMF
           RepID=A6TMX9_ALKMQ
          Length = 293

 Score =  245 bits (627), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 70/285 (24%), Positives = 121/285 (42%), Gaps = 26/285 (9%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y+++A+D+DGTLL  D  LS    E L      GI+    TGR    V    + L I  +
Sbjct: 3   YKLLATDMDGTLLMDDKALSTENIEALTRGKEHGIDLAICTGRPFPTVKPYLEQLGISCW 62

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
           ++T+NG+ + D   N+I+   +++D    +  +     D+  +V   +  ++   R    
Sbjct: 63  LVTNNGSVIRDKQENIIYEKFMEQDALEKIIDIFESEKDLYYHVSDANHTYIKSRRQRMR 122

Query: 122 RFFK----------------------EAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLP 159
              K                          +   +   +     V+ VF     + QL  
Sbjct: 123 TIQKFVSIKNMSPIKAYVTAAKMVFLSGTHKKVDFLSYVKNGGKVASVFVYSKDNIQLNR 182

Query: 160 LEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDA 219
           L++ ++      +NV+ S    +E++ G  +KGHALE ++KKL    ++ IA GD  ND 
Sbjct: 183 LKEKLSEI--KSINVTSSGSDNIEILDGNATKGHALEYLSKKLDIQAEEMIAVGDNYNDL 240

Query: 220 EMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
            M+  AG G  M +  Q + D      V  TN ++ V   + K+ 
Sbjct: 241 SMIQYAGLGVAMRNGEQAIIDEADW--VTKTNQENGVAFLMEKVL 283


>UniRef50_A8HYJ4 Haloacid dehalogenase-like hydrolase n=1 Tax=Chlamydomonas
           reinhardtii RepID=A8HYJ4_CHLRE
          Length = 323

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 67/270 (24%), Positives = 108/270 (40%), Gaps = 10/270 (3%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATG--RHHVDVGQIRDNLEIK 59
            +++ +D+DGTLL     LSP  +  +K   A G+  V ATG  R       +   L++ 
Sbjct: 42  IRLIVTDVDGTLLDSSQQLSPRVEAAVKEARAHGVPLVIATGKARGP-WTADVLLGLQLD 100

Query: 60  SYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
           +  +   G  V+D  G ++    L  D+A D   +  D   +    Y  D          
Sbjct: 101 TPGVFMQGLIVYDDQGRVLHERRLCEDVARDCITLAAD-VGVTLTAYCGDRILCAATDVH 159

Query: 120 EMRFFKEAVFQYALYEPGLLE----PEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVS 175
             R                         V K+ F     +++  L  A  A    R +++
Sbjct: 160 TDRLLFYKEPPPEPVGDLAAALGGGGVPVHKMIFMA-DQDRIDALRPAAEALLDGRASLT 218

Query: 176 FSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAH 235
            +    LEV+  G SKG  L  +   LG + +  +A GDG ND EML +AG G  MG+A 
Sbjct: 219 TALTGMLEVLPLGGSKGAGLSWLLDWLGVAPEQVLALGDGENDVEMLQLAGLGVAMGNAG 278

Query: 236 QRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            + +     + +  TN  D V   +++  L
Sbjct: 279 PKARAAAD-VVLAATNDQDGVAEAIQRFVL 307


>UniRef50_C4RHE6 HAD-superfamily hydrolase, subfamily IIB n=2 Tax=Micromonospora
           RepID=C4RHE6_9ACTO
          Length = 271

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 71/265 (26%), Positives = 120/265 (45%), Gaps = 6/265 (2%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           ++VA+D+DGTLL+ + TLSP  ++ L  ++ARG   V  TGR    +  +   L      
Sbjct: 7   RLVATDIDGTLLTDERTLSPRTRDALARMSARGTPVVLVTGRPIRWLQLVYQQLAEPLPA 66

Query: 63  ITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVN-DNPDIITNVYRDDEWFMNRHRPEE 120
           I +NGA V+D     ++ A  L   + +++   +  + P +   V   D   M       
Sbjct: 67  ICANGAVVYDPVTDEVLRADPLAPKLLAEVARRLRAEVPGVSFAVEIVDSREMRHETDYP 126

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           +R+  +A    A+  P  L      K+       +      + +          + S+ T
Sbjct: 127 LRWDADAEAIRAITSPEELHSVPAVKLLARAGEQDP-DVFLEVVAGALRGLAEATHSSYT 185

Query: 181 -CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +E+ A GV+K   L     +LG   +D +AFGD  ND  ML+ AG+G  + +AH  + 
Sbjct: 186 GLVEISAAGVTKAAGLAWYCARLGIDERDVLAFGDMPNDVPMLTWAGRGVAVANAHPAVL 245

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
            +    EV   N++D V  YL K++
Sbjct: 246 AIAD--EVTAANSEDGVAAYLEKVF 268


>UniRef50_Q04CZ3 Predicted hydrolase of the HAD superfamily n=2 Tax=Oenococcus oeni
           RepID=Q04CZ3_OENOB
          Length = 269

 Score =  245 bits (626), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 56/269 (20%), Positives = 95/269 (35%), Gaps = 7/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLE---- 57
            +++  D+DGTLLS    +     + ++    +GI  V A+GR    +      +     
Sbjct: 4   IKLITIDIDGTLLSSGQQVPKENIQAIRQAVNQGIKIVIASGRPLSGILPWLKIIGVPKA 63

Query: 58  IKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
              ++I  NG  +    G LI  + +D +    L    +   +    V   D        
Sbjct: 64  DDQFVIAFNGGVIQTTSGKLIAKNAIDYNGYKTLQNFADKQ-NAYFQVESLDGSHTISRL 122

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFS 177
             +    +  +   AL     +  +          S ++L  L   +  +     NV   
Sbjct: 123 IPKEAQMENYLINSALQIHDQMPEKVEFIKPMINGSQQELDRLISIVPKKIEKNFNVVRG 182

Query: 178 TLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQR 237
               LE M+   SKG AL  +   LG S    +A GD  ND  M  ++     MG+A   
Sbjct: 183 AWYNLEFMSKKASKGSALAILIDHLGISSDATMAIGDQGNDLSMFKVSNLAVAMGNAANE 242

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           +K       V  TN    V   + K  ++
Sbjct: 243 IKSKAD--FVTKTNNQAGVGFAISKFAIN 269


>UniRef50_Q5WEW5 HAD superfamily hydrolase n=1 Tax=Bacillus clausii KSM-K16
           RepID=Q5WEW5_BACSK
          Length = 269

 Score =  245 bits (626), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 15/273 (5%)

Query: 1   MYQ--VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI 58
           M +  ++A DLDGTLL  +  +SP  K  L     +G     ATGR +    +    L++
Sbjct: 1   MAKRHLIALDLDGTLLLKNQEISPRTKTALMKAKEKGHVIAIATGRPYRASKRYYQELQL 60

Query: 59  KSYMITSNGARVHDLDG----NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMN 114
            + +I  NGA VH         ++ +  L      +L             V   D ++M 
Sbjct: 61  TTPIINFNGASVHHPLDAHYPRILESIPLAYS--KELIKRCETIGVFNMMVEIGDTFYMK 118

Query: 115 RHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
           +       F  + V      E   L  E  + +       E++  L   +    G    +
Sbjct: 119 KQAGFFAEFLTDGVEPAGTGELHALVKEAPTAILI-EPKPEKVNVLHDTLQQT-GTETTL 176

Query: 175 SFSTLT---CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIM 231
                     LE+    V+K  ALE +A   G    + IAFGD  ND EM+  AG G  M
Sbjct: 177 QRWWKGETRILEIAPRNVTKATALERIANDYGIEQGNIIAFGDEENDYEMIEYAGHGVAM 236

Query: 232 GSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           G+A   +K +     V  TN  D +  YL K+ 
Sbjct: 237 GNAIDEIKAVADC--VTETNEKDGIACYLEKVL 267


>UniRef50_C4V674 HAD superfamily hydrolase n=2 Tax=Selenomonas RepID=C4V674_9FIRM
          Length = 275

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 61/265 (23%), Positives = 107/265 (40%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++A DLDGTLL+ D T++   K+ L    ARG+    ATGR           L  ++ 
Sbjct: 14  IKLIALDLDGTLLTSDKTITARTKDILARAMARGVTVTIATGRMLCSALYFVRLLGSRAP 73

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE-E 120
           +I  NG  V   +G+ +FA   D  +  +         D   N Y   E +   +R E  
Sbjct: 74  VICCNGGYVGTAEGDPLFARYFDPALVREFLAFCYAR-DWYVNWYNGIEIYAPEYRAECF 132

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
             +   A F         L        F   +    +      + A +G R+    +T T
Sbjct: 133 AAYRTTANFVVTEVGSDYLGCTENVPQFVLREMKSGVDSYVSEVRAHFGGRLVPQQNTGT 192

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            +++   G++K   ++A+A  +G +L + +  GD  ND +MLSM     +  +     K 
Sbjct: 193 SVDINPPGINKAVGVQALADAMGLTLDEVMVAGDADNDLDMLSMGAFSVVPANGLPAAKA 252

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                 +  +N ++ +   + K  L
Sbjct: 253 RA--SYITASNDENGIAAAVEKFVL 275


>UniRef50_C4IB07 Cof protein n=1 Tax=Clostridium butyricum E4 str. BoNT E BL5262
           RepID=C4IB07_CLOBU
          Length = 266

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 57/266 (21%), Positives = 124/266 (46%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           ++++ SD+DGTLL+  H +S   KE+L LL    I FV  + R    + +++  + + S 
Sbjct: 4   FKIIFSDIDGTLLNSSHEVSEKNKESLVLLNKLNIPFVLVSARMPQGIKKVQKEINVNSP 63

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVN-DNPDIITNVYRDDEWFMNRHRPEE 120
           ++  +G  V D +G  + +  +  + A ++   ++    ++ T+ Y  D+W  +  + E 
Sbjct: 64  IVCYSGGLVIDSNGKYLMSIGIRIEKAQEIKNYIDGKWKNVSTSYYSYDKWIADNKKDEW 123

Query: 121 MRFFKEAVFQYALY--EPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           +    +      ++     + E   V          + +  ++ +I+ ++   +++  S 
Sbjct: 124 IAQESDITSVNPIFGKIQDICEKNSVVHKILCMGDSKVIDEIKDSISEKYEG-LSIYKSK 182

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
            T LE+M    +K  A++ +       ++D I+ GD  ND +M+  AG G  M +A   +
Sbjct: 183 DTYLEIMELDATKSGAMKVLCDSFNIKMEDTISIGDNYNDVDMIKAAGNGIAMANAPDEV 242

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           K +    E+  +N +D V   + K +
Sbjct: 243 KRISN--ELTSSNDNDGVAEVIYKYF 266


>UniRef50_Q183K1 Putative hydrolase n=5 Tax=Clostridium difficile RepID=Q183K1_CLOD6
          Length = 262

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 55/264 (20%), Positives = 114/264 (43%), Gaps = 5/264 (1%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKS 60
           M +++A+DLDGTLL     ++P   +  K L  RGI F  A+GR + ++ +  ++++   
Sbjct: 1   MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGRQYQNLIKKFEDIKDDM 60

Query: 61  YMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
             I+ NG  V    G  I ++ L++++ +++             +      ++       
Sbjct: 61  MFISENGTLVV-YKGKEILSNPLNKELVNEIIETTRSIKGKKIVMSGKKYAYIESKEEAF 119

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
           ++       ++   E        + K+       +           ++ DR  V  S + 
Sbjct: 120 IQEVSTYYAKFKTVEDLTKVEGDILKIAVF--DFKGAEHNNNIYFEKFSDRAQVCISGVE 177

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L++ A G +KG A++ V K L    ++ + FGD +ND EM+  A     M +A++ LK 
Sbjct: 178 WLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEMMKSAYHSYAMENANEHLKQ 237

Query: 241 LHPELEVIGTNADDAVPHYLRKLY 264
           +         N ++ V   ++++ 
Sbjct: 238 IA--RFRAKRNTENGVVDKIKEVI 259


>UniRef50_Q1QY75 Cof protein n=1 Tax=Chromohalobacter salexigens DSM 3043
           RepID=Q1QY75_CHRSD
          Length = 266

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 88/261 (33%), Positives = 136/261 (52%), Gaps = 2/261 (0%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++ +DLD TLL+ +H L     ET + L ARG +   A+GRH  D+   R  L + +Y++
Sbjct: 5   LIVTDLDNTLLNAEHDLDELTIETFQALAARGHHLALASGRHFHDITAFRRRLGVPAYIM 64

Query: 64  TSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRF 123
           ++NGA ++  D +LI    +  ++   L  +     DI  N+Y  +EW ++   PE    
Sbjct: 65  STNGAHLYGPDDSLIAEQWVPAELVRALVELPR-GADIRLNLYTGEEWLIDASAPELKAL 123

Query: 124 FKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLTCLE 183
                F Y + +    +  GV KV       E L  LEQ+I    G R+++++S    LE
Sbjct: 124 HAHTGFHYRVADLEAHDGRGVGKVLCIG-DPEALAALEQSITETLGTRLHMTYSMAHSLE 182

Query: 184 VMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHP 243
           +MA GV+KG  LE +   LG     C+AFGD +NDAEML++AG G +M +AH  L    P
Sbjct: 183 IMAEGVNKGATLERLLAHLGLPAARCLAFGDNLNDAEMLALAGHGFVMENAHPDLPRRVP 242

Query: 244 ELEVIGTNADDAVPHYLRKLY 264
           +   IG +  + V   LR  +
Sbjct: 243 DAIRIGHHHPNGVAWQLRDFF 263


>UniRef50_A7GPW1 Cof-like hydrolase n=2 Tax=Bacillus cereus group RepID=A7GPW1_BACCN
          Length = 284

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 59/289 (20%), Positives = 112/289 (38%), Gaps = 31/289 (10%)

Query: 3   QVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYM 62
           +++A DLDGTLLS +  +S    E ++     G      TGR  VD+ ++   + ++  +
Sbjct: 2   KLIAIDLDGTLLSKNKMISKENAEAIRKCQEEGHVVAICTGRSIVDIERLLQEVNLQCPI 61

Query: 63  ITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMR 122
           I  NGA ++  D  ++  + +  + A D+   + +   +   +Y D   ++ ++  E +R
Sbjct: 62  IAENGAVIY-KDKTMLKRYAIQNEHALDIVEYLEEQ-GMYYQLYTDKGVYVPKYGEENIR 119

Query: 123 FFKEAVFQYALYEPGLLEPEG-------------------------VSKVFFTCDSHEQL 157
              E +    +                                   V K        ++L
Sbjct: 120 KEMEVIRNLDINISEEEVENIAALYLEHTAFHSIESCKSIINKELYVHKFLPFSYDQQKL 179

Query: 158 LPLEQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMN 217
             L++         + +S S    LE+      KG+ L  +A+      ++ +A GDG+N
Sbjct: 180 KRLKEKFQ--HNSELIISASYWHNLEINHCDAQKGNGLYTLAEYFNIPFENTVAIGDGLN 237

Query: 218 DAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           D  M+  A     MG+A   LK +        TN +  V H L    ++
Sbjct: 238 DVSMMQKANVSIAMGNAVNELKAMC--HYETLTNEEHGVAHALYHYVIA 284


>UniRef50_A0PYI8 Cof family protein , putative n=4 Tax=Bacteria RepID=A0PYI8_CLONN
          Length = 295

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 66/297 (22%), Positives = 125/297 (42%), Gaps = 34/297 (11%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK- 59
           MY+++  D+DGTL+  D TLS    E ++    +G+  V  TGR    + +    L +  
Sbjct: 1   MYKLIGIDIDGTLVKNDKTLSQKTIEAIEKARKKGVKIVLITGRPIEGLLRYTTKLNLNS 60

Query: 60  --SYMITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              Y I  +G  +  L +  ++F  ++     + ++ V N N  I  N+   D  +    
Sbjct: 61  DNDYGIACSGGFIQCLGNKQVLFESSITLKDFNYIYNVAN-NLQITLNILSKDTIYTPTL 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPEG-VSKVFFTCDSHEQLLPL--------------- 160
                     +     + +   L+ +  +++V +  ++      L               
Sbjct: 120 NLTTQIESFLSNIPMEIIDFNNLKDDICINRVVYINENKRFTDHLLNIIKRHNMEYKSSD 179

Query: 161 -----------EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDC 209
                      E ++ +   +   V   +   LE+ A GV+KG +L+ + +KLG    + 
Sbjct: 180 KLYGNNDLILDENSLPSELINNFTVLRPSSGTLEIQAKGVNKGSSLKILGEKLGIKRDEM 239

Query: 210 IAFGDGMNDAEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           IA GD  ND +M+  AG G  MG+AH+++K +     +  TN +D + H + K  L+
Sbjct: 240 IAIGDSGNDIDMIKYAGLGVAMGNAHEKVKAIAD--YITYTNEEDGLAHVIEKFILN 294


>UniRef50_C4L3T6 Cof-like hydrolase n=2 Tax=Exiguobacterium RepID=C4L3T6_EXISA
          Length = 270

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 64/263 (24%), Positives = 102/263 (38%), Gaps = 7/263 (2%)

Query: 4   VVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMI 63
           ++A DLDGTLL  D T+S      L+     G   + ATGR         + + + + ++
Sbjct: 5   LIAVDLDGTLLRDDKTISERNLRALQAAREAGHEVMIATGRPKRHSIMYYEQMGLTTPLV 64

Query: 64  TSNGARVHDLDG--NLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEM 121
             NGA VH        +    +    A D+   V D       V   D  +  +   E  
Sbjct: 65  NFNGALVHHPKDASYAVTHRPIPLKTAHDIIEEVADTKAHNIVVEVTDHVYFQKDPQEFY 124

Query: 122 RFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST--L 179
             + E               +  +       + + +  +   ++    + V         
Sbjct: 125 SPYAERALSVTSGNLLKHLQDEPTS-LLIHATKDHVAHVRSQLDDIHAEAVLNRQWRMPE 183

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +EVM+   SK   L+ V+K L    K  IAFGD  ND EML   G G  MG+A  +LK
Sbjct: 184 HMIEVMSKNTSKALGLQEVSKHLNIDRKHIIAFGDEENDLEMLDYVGTGVAMGNAIDQLK 243

Query: 240 DLHPELEVIGTNADDAVPHYLRK 262
           ++    EV  +N DD +  +L +
Sbjct: 244 NVAN--EVTASNMDDGIALFLEE 264


>UniRef50_C7HRV4 Hydrolase (HAD superfamily) n=1 Tax=Anaerococcus vaginalis ATCC
           51170 RepID=C7HRV4_9FIRM
          Length = 272

 Score =  244 bits (625), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 66/272 (24%), Positives = 121/272 (44%), Gaps = 8/272 (2%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-- 58
           M +++A+D D TLLS D T+     + +K     GI    ATGR    +  I + ++   
Sbjct: 1   MIKLIATDCDETLLSDDKTIHKRNIDAIKKAQEMGIIITTATGRGPYQLFDILEQIDNVK 60

Query: 59  -KSYMITSNGARVHD-LDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
              + I  NG  + D +   ++ A  +D   A ++     +   +   +Y D   ++  +
Sbjct: 61  EDRFSILCNGGIIMDNVTKKVVEASPIDYKKAVEISDYCKE-VGVHFEIYTDKHCYVFVN 119

Query: 117 RPEEMRFFKEAVFQYALYEPGL--LEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNV 174
             E    + + ++++      +  L+ E + KV     +   L+ LE+ I       +++
Sbjct: 120 GNEVEGNYDKNIYKFVQKAKDIKNLDKEIIVKVIIKNSNLNYLMSLEEDIARICNWDISI 179

Query: 175 SFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSA 234
           S+S+ T +E+    V+K  ALE +    G  +++ +  GD  ND EML  AG    + +A
Sbjct: 180 SYSSDTFMEINRKNVNKAKALEKLCAHYGIGMENVLTIGDNYNDKEMLEEAGYSAAVQNA 239

Query: 235 HQRLKDLHPELEVIGTNADDAVPHYLRKLYLS 266
           H  LKD+        TN   AV   + K  L+
Sbjct: 240 HLLLKDISKY-TTKATNNQGAVGEAIEKFVLN 270


>UniRef50_A3MZH9 Predicted hydrolases of the HAD superfamily n=9 Tax=Pasteurellaceae
           RepID=A3MZH9_ACTP2
          Length = 272

 Score =  244 bits (624), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 71/274 (25%), Positives = 124/274 (45%), Gaps = 17/274 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           YQ +A DLDGTLL+P  T+   +K+ +K    +GI   F TGRHH  V      + + + 
Sbjct: 3   YQAIAFDLDGTLLNPHATILESSKQAIKKAREKGIKVFFVTGRHHTAVRPYYAEIGLDTP 62

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           ++  NG  ++D     ++    L  + AS L         I T VY  D     +  P  
Sbjct: 63  VVCCNGTYLYDFQHDKVLSGKPLTAEQASHLINDAKSQ-GIHTAVYFRDAMTYEQLNPHF 121

Query: 121 MRFFKE----------AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            +  +            V+Q   ++  + +   V KV  +  + E++    + +     D
Sbjct: 122 AKLQQWVASCPESVRPNVYQLESFQQEIDKGTTVWKVLISDPNLEKMQNFVKKLP---LD 178

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
           + +  +S +  +++ + G SKG  L  + K  G   ++ IAFGD  ND  ML + G G  
Sbjct: 179 QFSPEWSWVDRVDITSVGNSKGAMLAELLKMEGLEPQNVIAFGDNFNDISMLELVGLGIA 238

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           MG + + +K    +   IG+N++D++   L +L 
Sbjct: 239 MGDSEEEVKQRADK--TIGSNSEDSIAKTLTELL 270


>UniRef50_C6PAK2 Cof-like hydrolase n=1 Tax=Thermoanaerobacterium
           thermosaccharolyticum DSM 571 RepID=C6PAK2_CLOTS
          Length = 267

 Score =  244 bits (624), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 66/265 (24%), Positives = 113/265 (42%), Gaps = 6/265 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           Y++V +D DGTLL+    ++   K +++    +G  F  ATGR  +      + L I   
Sbjct: 3   YKMVVADADGTLLNDKKEITVATKNSIEKFRDKGGIFTLATGRGILSATPYINELNIDVP 62

Query: 62  MITSNGARVHDL-DGNLIFAHNLDRDIASDLFGVVND-NPDIITNVYRDDEWFMNRHRPE 119
           +I  NG  +++  D  ++F   L  D+      +  +   ++   VY  D  F+N+    
Sbjct: 63  VILFNGCMIYNPVDKKILFEKYLSDDLYKLTANLWQEGRYNVDILVYSIDGIFVNKISDF 122

Query: 120 EMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTL 179
              +      +  + +  L     + KV F  +S   L  L   I     +      S  
Sbjct: 123 IKSYMAIEHVKCDIVD-DLSSLNKIIKVLFRGNSKTSL-KLVDEIRQLSDEPFTCVQSDE 180

Query: 180 TCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLK 239
             +E++  GV+KG AL  +   L   +K  +A GD  ND EM+  AG G  MG+A   +K
Sbjct: 181 FFIEILPYGVTKGSALVKLCNILDIDIKSVVAIGDQDNDREMILKAGCGVAMGNADDSIK 240

Query: 240 DLHPELEVIGTNADDAVPHYLRKLY 264
           +      +  +N +D V   L K+ 
Sbjct: 241 NSAN--YIAKSNLEDGVSDILEKVI 263


>UniRef50_C9LLD7 HAD hydrolase, IIB family n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LLD7_9FIRM
          Length = 266

 Score =  244 bits (624), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 66/266 (24%), Positives = 114/266 (42%), Gaps = 6/266 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI-KS 60
            ++ A DLDGTLL  D +LS ++K+ ++    RGI+ V ATGR         + L +  +
Sbjct: 3   IKMAAIDLDGTLLHDDMSLSDFSKDIIRKAEHRGIHIVLATGRMFDAARPKAEELGLSDT 62

Query: 61  YMITSNGARVH-DLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPE 119
            +I   GA +     G  I+   +D  +A  +     +    + + + DD+ ++      
Sbjct: 63  PLICYTGAWIMMSRSGRPIWQDGIDISVAEKILLTAREK-GWLVHTFFDDQIYLPEPNKT 121

Query: 120 EMRFFKEAVFQYALYEPGLL-EPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
           E ++ K      A          +  +++ F   S      + + I   + D V V F  
Sbjct: 122 EAKYKKYRTKAVAYLGNAFYHPKKKPTRLIFADGSEAVRREIRRVIETNFSDEVEVVFPG 181

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRL 238
              ++V   GVSKG AL+ +      SL + IAFG+  ND  ML MAG    + +A +  
Sbjct: 182 DDFVDVHKKGVSKGTALQKLCNMWDISLSEVIAFGNTENDVSMLKMAGISYAVKNADEYA 241

Query: 239 KDLHPELEVIGTNADDAVPHYLRKLY 264
           +       +  +N +D V   L +  
Sbjct: 242 RSAA--GNICDSNENDGVAKVLAEYL 265


>UniRef50_C4Z320 Putative uncharacterized protein n=2 Tax=Bacteria
           RepID=C4Z320_EUBE2
          Length = 268

 Score =  244 bits (624), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 65/269 (24%), Positives = 115/269 (42%), Gaps = 8/269 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIK-- 59
           Y+ +A DLDGTL + +  +    KE +      G+  + A+GR    +  I   LE+   
Sbjct: 3   YKALALDLDGTLTNREKKVPAGNKEAIAKAIDAGVKVILASGRPLFGITPIARELELDKK 62

Query: 60  -SYMITSNGARVHDLD-GNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
             Y++  NG  + D   G  + A  + +D  +D+  +   N  +    Y D +       
Sbjct: 63  GGYILAYNGGCIVDCKTGKQMSATIMPQDCIADICSLARAN-GVYALTYADTQIAAESDS 121

Query: 118 PEEMRFFKE-AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
            E ++             +      +   + F     HE+LLP+++A+  +    +N  F
Sbjct: 122 DEYVKKEAICNSTTIKKVDDLRKFVDYPVEKFLVVGEHEKLLPVQKALLDKHEGVINAFF 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S    LEV+  GV+K  +L+ +   L  + ++ +A GDGMND  ML  AG   +M +A+ 
Sbjct: 182 SESYFLEVVPAGVAKDASLDKLLTMLDITSEELVACGDGMNDIPMLKYAGLAAVMENAYP 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            +K          +N D  V + +    L
Sbjct: 242 EVKKYANVN--APSNDDCGVAYVIDNYIL 268


>UniRef50_UPI0001C17161 HAD-superfamily hydrolase subfamily IIB n=2 Tax=Nostocaceae
           RepID=UPI0001C17161
          Length = 294

 Score =  244 bits (624), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 57/276 (20%), Positives = 107/276 (38%), Gaps = 14/276 (5%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++  D+DGT+   D+ +S   K  +  + ++GI    ATGR +    +   ++     
Sbjct: 20  IKLLVLDIDGTIAGHDNQISETVKMAIAKVQSQGIQVAIATGRMYCSALRFHQDIRSSLP 79

Query: 62  MITSNGARVHDLDGNLIFAH-NLDRDIASDLFGVVND---NPDIITNVYRDDEWFMNRHR 117
           ++   GA + +     +  H  + + IA  L          P +  + Y  D+ ++    
Sbjct: 80  LMAYQGAWIQNPHTGELHRHLAVSKSIADQLLNYFEQPDLRPLLSVHFYLGDQLYVREMT 139

Query: 118 PEEMRFFKEAVFQYALYEPGLLEPEG------VSKVFFTCDSHEQLLPLEQAINARW-GD 170
            E   + +                         +KV       + +  L   +  ++   
Sbjct: 140 TETTIYVERCGVTPLAIGDLRQLLTDHDSSPGPTKVLALSHDVDLIQELLGKLRLQYTPA 199

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVA-KKLGYSLKDCIAFGDGMNDAEMLSMAGKGC 229
            + ++ S  T LEV    V+KG A+  +A + LG +  + +  GD  ND EML  AG G 
Sbjct: 200 ELYMTTSVSTFLEVTNPFVNKGTAVRYLAEELLGLTSDNVMTIGDNFNDLEMLEYAGIGV 259

Query: 230 IMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYL 265
            MG A Q ++ +     V     +D V   + K  L
Sbjct: 260 AMGGAPQPVQAIANW--VTAGVEEDGVAIAIEKFLL 293


>UniRef50_C9PP31 Phosphatase YbhA n=1 Tax=Pasteurella dagmatis ATCC 43325
           RepID=C9PP31_9PAST
          Length = 276

 Score =  244 bits (624), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 59/270 (21%), Positives = 106/270 (39%), Gaps = 17/270 (6%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
           YQV+A DLDGTLL+    +   +K  ++    +G   V  TGRHH         L + + 
Sbjct: 3   YQVIAFDLDGTLLNSKGQILTSSKAAIQRCINKGFKVVLVTGRHHTAAYPYYHELNLTTP 62

Query: 62  MITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEE 120
           MI  NG  V+    + ++ A+ L  + A  +  +      +   +Y  +E   +      
Sbjct: 63  MICCNGTYVYQPQTDSVLSANPLSFEQARTIIQLAEKY-GMHLLMYSRNEMNYSSLNEHM 121

Query: 121 MRFFKE----------AVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGD 170
            +F K            + + + +   L + E + K   +    + +     A+      
Sbjct: 122 RKFSKWVESCPEAIRPKIREVSDFNGLLKDGEIIWKFVISHPDRDLMQATVNALP---SS 178

Query: 171 RVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCI 230
             +  +S     ++   G +KG  L  +        +  +AFGD  ND  MLS  G G  
Sbjct: 179 EFSCEWSWFDRADIANRGNTKGTRLLELLNSWRIDPQAVVAFGDNHNDISMLSAVGLGIA 238

Query: 231 MGSAHQRLKDLHPELEVIGTNADDAVPHYL 260
           MG+A   +K+      V  +N ++ +   L
Sbjct: 239 MGNAETEVKECAKL--VTLSNDEEGIASVL 266


>UniRef50_C6DH90 Cof-like hydrolase n=1 Tax=Pectobacterium carotovorum subsp.
           carotovorum PC1 RepID=C6DH90_PECCP
          Length = 274

 Score =  243 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 64/268 (23%), Positives = 104/268 (38%), Gaps = 8/268 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
           ++++A DLDGTLL+    ++P     L+    +GI+    +GR    V QI D L +   
Sbjct: 3   FKLLAIDLDGTLLTSQKAVTPATCRILQEALEKGIHVALVSGRTLPSVLQIMDQLGLVGS 62

Query: 59  KSYMITSNGARVHDLDGN-LIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR 117
           + + I  NGA +   + + +I A  LD D    L    +        +    +   +R  
Sbjct: 63  RCWAIACNGALIWSQEKSAMISASVLDHDDILTLTHFGHSLNLECYQI-DGQQLVASRPV 121

Query: 118 PEEMRFFKEAVFQYALYEPG-LLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSF 176
             +    +       +  P         +      +    +  L   I      R     
Sbjct: 122 LSDAGALRYCRMPVVILPPDWETHSRRQTPKMMFVEGRTTIDALAGRIPPSLSRRYYFVR 181

Query: 177 STLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQ 236
           S     EVM  GV+KG A + +A  L       +A GD  ND EML+ AG G  MG+A  
Sbjct: 182 SEPNYFEVMQRGVNKGTACQTLAHYLAIPPAAILAIGDEENDREMLAFAGTGIAMGNAVP 241

Query: 237 RLKDLHPELEVIGTNADDAVPHYLRKLY 264
           ++K +     V   N  + V   L++  
Sbjct: 242 KIKAMADW--VTTNNDKEGVAVALQRYL 267


>UniRef50_Q1IMT6 Cof protein n=1 Tax=Candidatus Koribacter versatilis Ellin345
           RepID=Q1IMT6_ACIBL
          Length = 278

 Score =  243 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 57/265 (21%), Positives = 115/265 (43%), Gaps = 4/265 (1%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSY 61
            +++ SD+DGTLL P   L+   ++ +  +   G+ F   + R  +    + D L+I   
Sbjct: 6   IKLLVSDVDGTLLDPKKQLTEPVRQAVLRVKQAGLKFTIVSARPPLGTTFLIDALDITEP 65

Query: 62  MITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHR-PEE 120
           +   NGA        ++    L  D+A+ +   + ++  +   ++R  EW++++   P  
Sbjct: 66  IACFNGALTCTPQYEILHQILLAADVATQVAQTILEH-GLDLWMFRGAEWWVSKLNGPHT 124

Query: 121 MRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFSTLT 180
               K    +       +      +K+    D HE +   E+ + A+ GDRV+ + S+  
Sbjct: 125 EGHIKLMRHEPRYLGEDVTLCARANKLVGVSDDHEAVKRCEKDVIAKCGDRVSATRSSDY 184

Query: 181 CLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD 240
            L+V     +KG+A+  +AK +   L++    GD   D  M + +G    MG+A   +K 
Sbjct: 185 YLDVTDHDANKGNAVVQLAKLMDIPLENVATIGDMPTDMFMFAKSGMSIAMGNASDEVKA 244

Query: 241 LHPELEVIGTNADDAVPHYLRKLYL 265
                    +NA+      + ++ L
Sbjct: 245 AA--TFTTTSNAEGGYVKAMDEIVL 267


>UniRef50_Q1G860 Hydrolase (HAD superfamily) n=2 Tax=Lactobacillus delbrueckii
           subsp. bulgaricus RepID=Q1G860_LACDA
          Length = 268

 Score =  243 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 58/267 (21%), Positives = 99/267 (37%), Gaps = 8/267 (2%)

Query: 2   YQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDNLEI--- 58
            +++A DLDGTLL+    +SP    TLK    +GI  V  +GR    V ++ +  ++   
Sbjct: 3   IKLIAVDLDGTLLTSRKKVSPKTLATLKKAREKGILVVPLSGRPLPGVLKVFEPFKLDPA 62

Query: 59  KSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRP 118
            ++ I  NG  V  +DG ++ A  L  +    +  +          +   D +   +   
Sbjct: 63  DNFAICYNGGLVQRMDGEVLSASPLTDENVEHMLALKQTGIFGPYFMDTKDFYVAPKGSS 122

Query: 119 EEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPLEQAINARWGDRVNVSFST 178
             + F  +A              E +   F +     ++       +        +S S 
Sbjct: 123 FGVGFLAKARNMGVKRMVPGQHYEFIKGEFVSL--PSKIKKFRAGFSPATEQEFEISASG 180

Query: 179 LTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAG-KGCIMGSAHQR 237
             CLE    G SKG AL  +   L    ++ + FGD  ND     + G     MG+A   
Sbjct: 181 GQCLEFNTPGTSKGQALTTLLDLLNIQPEEAMVFGDNNNDLSDFQLPGVFKVAMGNAIDE 240

Query: 238 LKDLHPELEVIGTNADDAVPHYLRKLY 264
           +K       V  +N  D +   + K  
Sbjct: 241 IKAAAD--YVTASNNQDGIALAVEKFV 265


>UniRef50_A9BES4 Cof-like hydrolase n=1 Tax=Petrotoga mobilis SJ95
           RepID=A9BES4_PETMO
          Length = 277

 Score =  243 bits (623), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 62/272 (22%), Positives = 120/272 (44%), Gaps = 12/272 (4%)

Query: 1   MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGRHHVDVGQIRDN----L 56
           M +    DLDGTLL+ +  +SP   + LK L   G   + A+GR +     + +N    L
Sbjct: 1   MKKTFVFDLDGTLLNSEVRISPKTYQALKRLKEEGHIIIIASGRMYASTMYVVENFLPFL 60

Query: 57  EIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRH 116
           +    + + NG  + D +G ++F   +  + A      + D  +I  ++Y +D+      
Sbjct: 61  KGNVIISSYNGGYIVDHNGKVVFEKGVANESAIKCIKFLRD-LNIHRHIYINDKLISEID 119

Query: 117 RPEEMRFFKEAVFQYALYEPGLLEPE----GVSKVFFTCDSHEQLLPLEQAINARWGDRV 172
             E   + K +   Y L +  + E E       K+    +  +++  +++          
Sbjct: 120 DKEIRDYSKHSFVDYVLVDDLIAEIETSSHPTLKILAIGE-PDKIDVIKKLAENELQGEF 178

Query: 173 NVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMG 232
           N+  S  T L+ +  GVSKG++L+ ++K           FGD  ND +ML +      MG
Sbjct: 179 NLMKSWDTYLDFIPYGVSKGNSLKIISKIYNLDPNTLYVFGDSENDIDMLELTKNSFAMG 238

Query: 233 SAHQRLKDLHPELEVIGTNADDAVPHYLRKLY 264
           +A + +K +     ++ +N +D V + + K+ 
Sbjct: 239 NAKEDVKKVAN--YLLPSNDEDGVAYAIEKIL 268


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.314    0.206    0.693 

Lambda     K      H
   0.267   0.0633    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,216,312,817
Number of Sequences: 3077464
Number of extensions: 145654020
Number of successful extensions: 396649
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 4743
Number of HSP's successfully gapped in prelim test: 1727
Number of HSP's that attempted gapping in prelim test: 380255
Number of HSP's gapped (non-prelim): 9145
length of query: 266
length of database: 1,040,396,356
effective HSP length: 126
effective length of query: 140
effective length of database: 652,635,892
effective search space: 91369024880
effective search space used: 91369024880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (20.9 bits)
S2: 93 (39.8 bits)
