Reference sequence (query): batch____ Identities normalised by aligned length. Colored by: property
HSP processing: ranked Search cycle: 3
1 [ . . . . : . . . . 1 . . . . : . . . . 2 . . . . : . . . . 3 . . . . : . . . . 4 . . . . : . . . ] 488
batch____ bits E-value N 100.0% 1:488 MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLVEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDEQAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHQGRETDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQALLNTLKI
1 UniRef50_P33029 Uncharacterized oxidoreduct... 597 1e-169 1 100.0% 1:488 1:488 MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHSAPGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLVEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDEQAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHQGRETDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLREVFGDDLPDNPHFVQAIEQAWQQIVQFGAHQALLNTLKI
2 UniRef50_C6D940 Mannitol dehydrogenase doma... 572 1e-161 1 61.9% 3:487 7:492 --NIATCELPASVQFPRYDRKALKPRIVHIGFGAFHRAHQALLTDRVLNMVGGDWGICEVVLFSDDTMINALRQQDHLFTVLEKAATSNQPIVVGAVCESLHAKIEGINAIIEKLAAPETAIVSLTITEKGYCMDGTSGKLDRTNKLIQQDLIDPRRPVSVPGLLAEALRLRHERGIAPFTVLSCDNVPENGKTAKAAVLESAGINDRNLIDWIEAQVSFPNTMVDRIVPAATPETLQEIADHLGVADPCAIACEPFIQWVIEDHFTAGRPEWEKAGVQLVHDVLPFEEMKLRMLNGSHSFLAYLGYLAGYDHVSDCMNDENYRRAVSHLMLLEQAPTLSVVDIDLKDYAVQLLTRFSNPALKHRTWQIAMDGSQKLPQRMLESLRWHVSNGGDYRCLALGIAGWMRYVSGKDDAGNPIEIRDPLADKLRHVVEesDSAERVSAFLNIRSIFGEDLPANHDVFNAIAQAYLKLRDHGAKNTVAALAQ-
3 UniRef50_Q21M76 Mannitol dehydrogenase-like... 571 1e-161 1 46.3% 1:484 4:488 INNDLLASvsSAIQLPQYDRAGVKPGIVHLGIGAFHRAHQAFYTEAVLNQFGGDWGIIGCSLRSA-SVKTQLAEQDGLYTLVERGPEGEKFQIMGAVQQVVVGPEDP-AALVAIMANPQTQIVSLTVTEKGYCHDPATGNLNLSHPDIQHDLGNLNAPKSAIGYIVAALLARKESGQSSFTVLSCDNLPNNGEVLEKVVLQFAKQVSAELCEWVSAHTKFPSTMIDRIVPATTDSDRADLEAKVGYRDEGMVVAEPFTQWVIEDKFCSARPQWEQVGALLVEDVTAFEKMKLRLLNGSHSMLAYAGYLAGFETISDVMTEPAFVALCKKFMDTEAGPTVKTpgFDIEDYKKQLRDRFANPGLKHRTWQIAMDGSQKIPQRLLETLREQLASGGSIEVISLAIAAWFKYVSAVDDAGNAIDVQDPLAARLKSLCDShnTSERVAALLGVKEVFGEDLVGCSAFAAAISAWLDAFAKQGVLATIKQ----
4 UniRef50_B2SAL5 Mannitol dehydrogenase n=45... 561 1e-158 1 46.1% 1:488 11:498 LSNRTMSGLPSSVKVPAYDRSRITTGIAHLGIGAFHRAHQTAYTDAVLTSGSNEWGIVGVSLRRPDT-RDALQIQDELYTLAIRDGDSEKLQVIGSIQNILVAPEDP-QAVLDIMSHPDTRIVSLTITEKGYCRDAAVSGLDRSHPDIIYDLAHPATPRSALGFITEALRRRRAQGTAPFTVLSCDNLPANGETCKNVIVQFAGCTDTDLAHYIEETVAFPSTMVDRIVPATTDEDRISISRTLKVLDQWPITTEPFSQWVIEDRFPTGRPAWEIAGATFVQDVAAFELMKLRLLNGSHSTLAYLGFLAGHRTVSQTMAAPGFKQLIKALMEIEIAPTLplEGFDLSSYQAALIHRFENHALHHLTSQIAMDGSQKLPQRLLNTIQERLDGGGSIDRLALGVAAWMRYVTGKDEAGTPIDVRDPLSGQLLDQTQGkaPDEIMDALLSFRQIFTARLAANELFREKLRLALGSLYAVGSAETVRRYAEI
5 UniRef50_P39941 Mannitol dehydrogenase DSF1... 558 1e-157 1 37.6% 1:487 12:500 LNAKTLKSFESTLPIPTYPREGVKQGIVHLGVGAFHRSHLAVFMHRLMQEHHldWSICGVGLMKADamRDAMKAQDCLYTLVERGIKDTNAYIVGSITAYMYAP-DDPRAVIEKMANPDTHIVSLTVTENGYYHSEATNSLMTDAPEIINDLNHPEKPDTLYGYLYEALLLRYKRGLTPFTIMSCDNMPQNGVTVKTMLVAFAkkKDEKFAAWIEDKVTSPNSMVDRVTPRCTDKERKYVADTWGIKDQCPVVAEPFIQWVLEDNFSDGRPPWELVGVQVVKDVDSYELMKLRLLNGGHSAMGYLGYLAGYTYIHEVVNDPTINKYIRVLMREEVIPLLPkpGVDFEEYTASVLERFSNPAIQDTVARICLMGSGKMPKYVLPSIYEQLRkdGKYKLLAVCVAGWFRYLTGVDMNGKPFEIEDPMAPTLKAAAVKGG--KDPHELLNIEVLFSPEIRDNKEFVAQLTHSLETVYDKGPIAAIKEILD-
6 UniRef50_B9JSW9 Altronate oxidoreductase n=... 532 1e-149 1 45.3% 3:485 6:487 --PADISANPQRLRRPDSIRPQ--TGIVHLGLGAFYRAHGAIYIEQAMEKSGGDWGIIGVSLMRPDQ-RDALAPQDFAYTAVELGPNGETPHVIGVINDVLVA-RENQRAVIDAMSDPAVKIVSLTVTEKGYCHEPSTGKLNRNHPDIQHDLAYPEAPVSALGFLVRALEKRHAAGLRPFTVLCCDNLPENGKVVRGVVLELAGLISSDLQGWIASEGAFPSTMVDRIVPATKPEDIDRLAQITGVLDLSPVMHEPFRQWVVEDHFVDgrPDLGAVGVELVKDVTPFEHMKLRCLNGTHSSLAYLGYLAGHETIAQTVADPVFARFCKMLWDTEITPGLkpPGISLGDYTAALFDRYANPAIRHRTWQIAMDGSQKLPQRILGTLTENLAANRPITGLALAVAAWMRYVGGIDEKGDAIDVRDPLATRLKSLSDgaEPAEKVAALLSVREIFPAPLADNPTFRNALTTAYQSLVTKGARQTIEDL---
7 UniRef50_UPI000197C908 D-mannonate oxidoreductase ... 528 1e-148 1 49.1% 20:487 19:490 -------------------KPLLIPRIVHLGCGAFHRAHQALYTHLLFEQFLSNWGYCEINLMsgAVLINQLNKYNGHYTLLEKDEEKSTVRTIKVIKEAMHPRIDGIDAVVEKMASPDTAIISLTVTEKGYCLSPATDLLNLSHPNIQHDIAHPTKPRSVLGYIVASLRLRFQRQQPPITILSCDNIRKNGEAARRAIVGLAAQQDKQLAQWIDQHISFPSTMVDRIVPAMTQESYAEIKQLIGRDDPCAIICESFRQWVIEDNFVNGRPDWQHVGAQFVPDVTPYEMMKLRMLNGSHSFLAYLGYLGGYEFISDAMQNSDYSRAAYSLIINEQAPTLFIpnTTLLQYTQTLIKRFSNKTIKHKTAQIAADGSQKLPQRLLDSIMWHQKHGSDYAFLALGVAAWMKYVSGQDEQGNAIDIKDPLQHKFAEIYHLCGVgeAVDRLLAINAIFPLEFSQNQDIVKNVKTAYQQLISVGARETVKHYLQ-
8 UniRef50_B4WTN2 Mannitol dehydrogenase ross... 527 1e-148 1 38.3% 1:486 27:524 LNSAALARYPQQVRIPRYDRASITASVVHIGVGGFHRSHQALYIDNYIEKATEnwGICGVGLLKYdkMRNVLQSQDCLYTLVERSSKQDTARIIGSITEYLFAPEEP-QAVIDKLADETCRIVTLTITEGGYYVIEGTGEFDSQHPNIQHDLQFPDQPASVYGFLTAALKKRWQQGLPPFTVLSCDNVQGNGNIASKMLSAFAKLQDPDLEQWIAENVTFPNSMVDRITPATTPADIQMVAEQFGIEDRWPVVAEPFIQWVIEDNFCAGRPRWESVGVQMTDDVHPYEMMKLRLLNASHSLLGYLGSLLGYTYTSEAMEDNLIRRAIAQLMDEVTPTLLPLPNVDIEDYKTTLIERFSNPKVRDQLSRLCLNGSDKLPKFVFGSLQDKLAQGGSIKHLSFVVALWFRYLNGKDEQDQPIAINDPLSDLLTNRAKAGGPD--PTQLFAITTLFGS-LSKHPSVIDTVTYHLQQLYALGVEKALVELL--
9 UniRef50_D2S6P7 Mannitol dehydrogenase doma... 527 1e-148 1 39.9% 1:486 4:489 LSTATLASLGGSLSVPSYDRSSVRTGIVHLGVGAFHRSHQAMYLDRLMEEGKadWGICGVGVLPSDrmAEVMAAQDGLYTLVVKHSDGrdARVVGSVVEYLLAP-DDPDAVVEKMAAEDTRIVSLTVTEGGYNIAAITGEFDPTHPDVVSDLRPGAALRTSFGLVTEALVRRRDRGLAPFTVVSCDNIQHNGDVARRSFAAFAALRDPELGAWVEREVPFPNSMVDRITPATTDDDRAEVARRFGVDDAWPVVCEHFTQWVLEDRFGLGRPPLEDAGVQIVDDVDPYERMKLRLLNASHQALAYLGHLAGYRLVHDAAQDPLFQRFLLGYMEEEATPTlpVPGIDLEDYRRTLIARFSNPHIRDTLARLAFDGSERLPKWLLPVVRDQLARGGEVRRSAAVVAGWARYSEGVDEQGRPIEIADRRRDPLMAAARRER--EEPLAFLADRALFG-DLVDDERFTGPYLAALASLHERGARATLEALV--
10 UniRef50_B2TGB7 Mannitol dehydrogenase doma... 524 1e-147 1 42.8% 13:486 19:491 ------------VVVPAYDRASLAPGIVHLGLGAFHRAHQALYTEHALRAGDHRWGIVGVSLRRADT-SEALTAQDHLYAVDVRDGTADSLQVIGALIASLVAPQSP-AAVLDAMTDPRCHIVSLTITEKGYCRNPASGALQFDHPDIAHDLRAAAAPRSAIGFVVRALALRRAAGLGPFTVLSCDNLPSNGDTMRALTLAFARETDPALADWIELEAAFPNTMVDRIVPLTTDADRLRVAKQLGADDAWPVITEPFSQWVIEDRFAGPRPAWERAGATLVGDARPYEQAKLRMLNGAHSALAYLGSLIGYDTVDQAIGAPAVLNFVESMLRDEVEPTLSRPA--LATYRAELFARFRNTALDHRLQQIATDGSQKLPQRWLESVRANLKSGAPTERLAFALAGWIAYLGGHDETGRTYAIADPLADRLTEAVRaaDAADAVRTLFEIEPIFGRDLCAHPRFVAQVARHLAAIRAQGVVKAMDAFA--
11 UniRef50_B6R9L2 D-mannonate oxidoreductase ... 522 1e-147 1 47.4% 3:487 7:492 --KLDLNALPSDVSVPSYDRESLKPRVAHIGFGAFARAHVAMHLHETLAAGGGDWGMRVIELFGTSDLFDKLEENDHLYTLVETADEGTNTRLLGAVCETQHLARDGVEALINGLAEEQLKVISLTITEKGYCVK--NGKLDLDNAMIQQDLSTPSAPKTAIGLIVAGLAKRRALGNGPITVMSCDNLPHNGVLCGIAVREFAAKLDAELAAWIEENVSFPSTMVDRIVPALTDESRELIRESLGGqdLNGIVCEPFRQWVIEDNFKAGRPQWELAGAQLVADVEPFEEMKLRTLNGSHSFLAYLGFLAGKETIADCAADPVFYAEARKLMVDEQLPTLDVPgvDLVAYADSLLKRYSNSKLKHRTWQIAADGTQKMPQRWLNSVRFHLANGGDYRHLVLGIGGWMNYIRA-DRNGESYEVVDPLKEKLAAIVANDGADEtvDTLLALDSVFPSELVANDEFKKAVHNAYRAVAEKGAAQAVADLAD-
12 UniRef50_B2TDP7 Mannitol dehydrogenase doma... 522 1e-147 1 44.3% 1:485 10:495 LVRQALPTLQTHLLSPLW--QEPRIGIVHLGIGNFHRAHQALYTEEAMLAAGGDWGICGVTLQGDVGKRDALMEQQGLYSVVERGPHGAKVTVVRALREVLAMPHDQ-AALFARLADPAVRIVSLTVTEKGYCRDPRTGEVALDNPAVAHDLASPFEPRTVPGILVAALRQRHdaRGQPFTVLSCDNLSHNGAALRQVVCSFARQLDPALADWIAAHVAFPSTMVDRIVPATTHAESVTVAHAIVYQDAAPVPCEPFRQWVIEDRFPAGRPAWDAVGAQLVDDVTPFELAKLRMLNGTHSTLAYLSMLGGFETIDAAISYPPMRNLIHAMMTEEIAPTLTMpsFDLSAYRDALLERYANPALKHRCSQIAMDGSQKIPPRLLDTIAARIDAGQSFTRLVLAVAAWMMFLRGHADDGTRYEISDPLASRLHALaaHDDPQALMDALLSVREVFPADLTAFPEFREALLRALRLLREEGARGAIAAL---
13 UniRef50_A6WFS9 Mannitol dehydrogenase doma... 521 1e-146 1 40.7% 1:486 12:493 LREENLGDLPADVAVPGYDRSALRPAIVHIGVGGFHRAHQAVYLDDLARTGETGWGLVGVGLRSPE-MGQVMADQDRLYLLVERGDDADRARVVGVVDRYLFAP-DDPEEVLRTLADEETRLVTLTITGTGYRIDPHTGEFDADDDDVRADLADPAAPRTVFGFLAEALNRRRRAGLVPFTVLSCDNVPDNGAAARTAVASFARLRDPELADWIEAEVAFPGSMVDRITPTTTPEERDAIAAATGVDDRWPVITEPFTQWIVEDSFCNGRPPLDRVGVQFVEDVAPYKAMKTRMLNASHCALAYLGILAGFSTIDEVLADDTFRAYLEHLMDDEIAPLLPppGVDLEDYRRSLVRRFSNPKMGDQLGRLGRRGSTKMPDYVFPSVSAAIEAGRPHQLLLLAVAGWMRFLRGYDYAGNDVPVSGPLSERLVELAREGLTE--PEALLTERSVFG-GLGDDAGFVAGVEVALRALEEQGPREVIALYL--
14 UniRef50_Q164Y8 D-mannonate oxidoreductase,... 521 1e-146 1 45.1% 15:486 4:478 --------------PPRLQRQNKAPGivHLGPGAFFRAFNAVYTDEAMALNGGDWGILAVSLQSARA-REELAPQGCVYTSVSMGPEGEETRLVNAISDVMVAPQNP-DAVLRAMARADVKIVSLTITEKGYCRDPSTGGLDVQHPDVQHDLSTPAMPKTAPGLIVKALARRRAVDERPFSVLSCDNLPDNGATTRRIILEFARKRDPELAAWIAQQARFPSTMVDRITPATTPADIDALAQRSGYHDAALVRHEAFRQWVIEDDFVDgrPAWDKVGAQFVTSVTAHEKMKLRCLNGTHSTLAYLGYLAGYETIAETVADASFAALCTTLWHREILPTIPApgEDLQAYVAALLARYQNPAIRHLTWQIAMDGSQKLPQRILGTIADGYAAGRAPDGLCLAVAGWMRYVGGVDENGAAIDVRDPLAARLraSDSAQSAAGKVDALLDIRDVFDEALASNPDFRRAVHGAYETLVSKGAGGAVADYV--
15 UniRef50_Q21L96 Mannitol dehydrogenase-like... 521 1e-146 1 42.7% 1:485 6:489 LNYESLSNVLDPVKKPQYTPSEHRSGIVHIGIGAFHKAHQAVFTDDVLNMHGGDWRITAVSLRRPDA-RDQLEKQNSLYTVVEKSDGEISPRIIGAVEKVLVCPEDP-QQVINTIASTDIKIVSLTITEKGYC--QKNGTLDTSNVDIAHDLNNLSAPKSMPGLIVAACAARKQNNANGFTVLSCDNLPHNGKITQNVVMRFAEKVDAELASWIATHISFCSTMVDRIVPATTSADLDEVKNLIGLADDAAVICEPFRQWVIEDNFVAGRPQWEDAGALLVADVTPYEDMKLRLLNGSHSALAYLGFLSGFDFIHQAIANPRLLALTKKLMDEDVTPTLNVpgFDLDAYKAIIRTRFANSRVPYKTTQVANDGSQKLPQRILAVADHLISGGKQPAVIPAIIAAWFQFLEGQDTHGEQHTVNDPLANTLCPLahKANDTKQVQELVAASQIFPEGLIANTEFINSIEHYLAKFHAKGVLTTLAEL---
16 UniRef50_Q3ID77 D-mannonate oxidoreductase ... 516 1e-145 1 37.0% 1:487 14:503 LNQQSLAQLPSHVDTPSYDRSAVKAGIVHIGVGGFHRAHQAVYVNELLKtgSEQWGICGVGLLenRGLRDILKQQDYLYTLTVRHPDGkdNKVIGSMIDFLFAPEDK-QAVINKLAHSDTKIVSLTITEGGYNFNPATGEFDYSNPDIINDINNPNDPITAFGYITAALKLRKEQGLGAFTVQSCDNIQHNGNVTRKMLLAFATEQDKNLSEWIEQNVSFPNAMVDRITPVSKKSDIDYVVDAYGVSDEWPITCESFTQWVIEDTFSDSRPNWDVVGAQFVTDVTPYETMKIRLLNAGHSVLGLLGSIHGYGTIDETVSDELFATYLRAFMDKEVTPNlpLEGIDLQSYKDTLIERFANPNIKDSLARICSESSAKLPKFLIATINENLVQGRDVSLATLVIATWCLydKGVSEKGEKLEIQDAMYKELNSYAQE--TQTSPIAFLKLTSLFGK-LEHNETFTAEYKKSIAALYasKIKAIMQAVLE-
17 UniRef50_C6YVN6 Predicted protein n=1 Tax=F... 515 1e-144 1 37.6% 4:485 2:488 ---LNLQKL-HNCSLPNYQRNNLNPGILHIGIGAFHRAHQVFYINKLLNTGdlNWGYVSGTIRSNQKLIDDLKANDCLYTLSTNDESGTKNTIIGALKDVYFAGNGQSQSLITKISDPNIRIISYTVTEKGYYVDLSTQELNFENPDIAYDLVNINSPKTAIGITVAGLYKRWNKNAKAITLLSCDNMPNNGKILKKAILEFSSKIDKQFSTWVAENVSFPSSMVDRIVPAVTQQTLDNIENMIGQKDISAVATEEFSQWVIEDNFANGRPALEKVGVEFVKDIEPFEKLKLTMLNGSHSLIAYLGAYAGLKTVDEVIVKPEFYNFIKKYMLKIAAPLVdpQEISTSEYANKLLHRFANPHLKHKTEQIAMDGSKKIPQRWLGSLAHLLENKQNYDILALGIAGWILFCSGKDQYGKILEISDPLQNGYKLIYQENtiTDIVNCFLSLKSIFPETIAINNDLKEKIVFFIEEINKYGVIKTLTKL---
18 UniRef50_C5CMZ2 Mannitol dehydrogenase doma... 512 1e-143 1 42.1% 1:484 4:503 LNAEMLAALPPAVARPAYDRAALEAGIVHLGVGAFQRGHLAAVNEAALHagDLRWGIAGVSLRSPDT-RDALAPQDGLYTLTLRDVDEasLQVLGCLLGVQVAPEDP-AAVLARIAHPATRIVSLTVTEKGYCHDPATGALRADHPDVLHDLARPDAPRGTLGFVVSGLRLRQLRGLAPVTLLSLDNLPSNGHLLRGLVLDFAQRVDPQLARWIAEHCSFPCSMVDRIVPRTTDADRAQVDAALGLEDAWPVVGERFLEWVVEDDFAAGRPAWDAGGARFVPDARPFETLKLRMVNGAHSALAYLGAMAGLDTVDRAVATPALHRYLDRLMREEIAPTLplPGLDLDAYRQRLLERFANPALAHRTAQIAMDGSQKLPQRLLGTVRERLAAGASIDRLALAVAAWLHYLRGIDELGRRHEIQDPLADAlaAAEPAQADEARVAVFAAFAPVFGNDLGSNPRFVSAVATQLRALRELGVHKTLAD----
19 UniRef50_Q1NAI9 Putative D-mannonate oxidor... 511 1e-143 1 41.4% 1:485 4:486 LSRHHLKSLPHDVRRPSYDRAAVRAGVVHLGIGAFHRAHQAAIFEEALNAGDLRWGIIAASLRSP-AVRDQMAPQDGLYTVLVRDGSADRAQVIGAVRQVIVAPEDP-EALLAALAAPDTHIVTLTVTEKGYKLDPATGGLIEGDAQVAADLVSLKAPQTAPGYLVAALARRKKEGLTPFTAISCDNLPHNGQRLRGAVLDLARRHDPALADWIAAEGAFPETMVDRIVPATTADDVAALGRRLGVEDQAMVKTEPFLQWVIQDWFCGPRPTF-GAGVQVTAAVAPWEEAKLRLLNGAHSGIAYLGGLAGIDHVHEVLTLPEARAFVEALWDEAEATLTPPPELDVAAYRRDLMARFDNPTLRHRTRQIAMDGSQKLPQRLLAPIAARLEEGQGVDALSLAVAAWIRWQAGVDDQGAGHVVDDPLARPIAEALSGadSRGRVDAILALGAIVPPKLAEHAAWRETLMKWLSVLETHGARAALAKL---
20 UniRef50_D2SB75 Mannitol dehydrogenase doma... 510 1e-143 1 38.7% 1:488 37:521 LTQATLYSHGARIAVPTYDRAALTPSVVHLSVGGFSRAHQLIYFDELAERrsTGWGVVGVGLRQ-RHLQDALAPQDHLYTVVERSPDGERARVVGVMVDYLYAP-DDPAAVLDRLSDPRTRLVTLTITPDGYLLDPQTRAFTADHPDVLRDLAEPHAPATVFGYLVEALDRRRKAGLAPFTVVSCDNLHRNGEAARASVVGLARLRDEVLARWITDGVAFPSSMVDRITPQTPPEERAALAARYGVDDRWPVVTEPFSQWFVEDTFSHGRPPLDEVGVRFVPDVGDYELMKTRLLNASHSALGHLGSLAGYDRMDELMGDPVFATYVERLMDDEVTPLLPQpgVDLADYKRTLLQRFANPAIADRLSRLCRRGSAKLPQHLLPSLRQSLVEGRPAPLLLLAVAGWCRYLRGTDDDGRPLPLEDPRADELRALALAGGGD--PRPLLGVRAVFG-DLGDDPVVVAALTGAIETIDRLGARAAVAAALDV
21 UniRef50_Q742F6 Putative uncharacterized pr... 509 1e-143 1 35.1% 1:487 21:503 LSNATLPLHSQRIDVPTYDRSALQRGVVHIGAGNFHRAHQAVYFDDLACSGISdwGVSAISLRSHD-VKDLLSAQDGLYTVVQRGHDHQTARVVGSIGSVHYAPNDG-AAVRAALTDPRTRIVSLTITPNGYFLDPVTREFDADHPDVRADLVASGCYGTAWGYLTEALEQRRRAGIAPFTVLCCDNIPDNTQAARTALVSFAALKNPGLARWIDRHVAFPSTMVDRITPQTSDSEREFVERTFGVADNWPVLTEPHSQWIIEDAFSDGRPPLDEVGVQFVTDVSDHKLIKTRLLNGTHIALACLATLAGYRRTDEAMKDPVIFDYVERLMRDEVQPLLPppGMNTPDYRDTLLTRLGNPRMSDQLSRLARRGSTKIASFLLPSLHEAIAQDRPHTLLMLALAGWARYLRGYDLNGRKIRIDDPEADLLTKLANMAG--NNPDPLLRHEIL--ADLRLVPGFSERLGEMVASIDEHGVIATLRQSLQ-
22 UniRef50_B7UIR8 Predicted mannitol dehydrog... 508 1e-142 1 48.1% 1:486 1:485 MSGNESIDAAHYDQVTTWPRGGLQADIVHIGFGAFHRGHQAVYTDLTNQLSDTRWGIFEINLFGDAQLIENLNAQNGLFSVVETSASQSTSRLVRSVAGGIHTPRDGIAAAIHKLAEPQVKIVSLTITEKGYCLDPQTRSLDLTNGLINHDLQNPDAPQSAIGVIVCALQQRKAAGLAAFSVLSCDNLPDNGHLTRNAVLGFARQLDQPLAQWIEENVSFPGTMVDRIVPAMTESQFALLETKTGYADPCGIVCESFRQWVIEDNFVRGRPEWDKAGAMFVSNVQPYEEMKLRMLNGSHSFLAYNGSLAGYEFIWQCMEDADFRSITRQLMINEQARTLNPdnIDAQEYADLLIERFSNRNVAHRTGQIAMDGSQKLPQRALTPWLKLHQQKQNNAVLSLLVAGWLHYV--IDAVEKSQSVADPMNDQLQALIKeqDAWQQALALLHLSAIFG-DLSNHQPFINEIKIAFANIKNKGIKATISQLL--
23 UniRef50_C7GXF5 Dsf1p n=1 Tax=Saccharomyces... 507 1e-142 1 35.9% 1:487 12:467 LNAKTLKSFESTLPIPTYPREGVKQGIVHLGVGAFHRSHLAVFMHRLMQEHHldWSICGVGLMKADamRDAMKAQDCLYTLVERGIKDTNAYIVGSITAYMYAP-DDPRAVIEKMANPDTHIVSLTVTENGYYHSEATNSLMTDAPEIINDLNHPEKPDTLYGYLYEALLLRYKRGLTPFTIMSCDNMPQNGVTVKTMLVAFAkkKDEKFAAWIEDKVTSPNSMVDRVTPRCTDKERKYVADTWGIKDQCPVVAEPFIQWVLEDNFSDGRPPWELVGVQVVKDVDSYELMKLRLLNGGHSAMGYLGYLAG--------------------------------SVDFEEYTASVLERFSNPAIQDTVARICLMGSGKMPKYVLPSIYEQLRkdGKYKLLAVCVAGWFRYLTGVDMNGKPFEIEDPMAPTLKAAAVKGG--KDPHELLNIEVLFSPEIRDNKEFVAQLTHSLETVYDKGPIAAIKEILD-
24 UniRef50_A6VZ13 Mannitol dehydrogenase doma... 505 1e-141 1 43.9% 18:482 11:481 -----------------YAPEKVDVGIVHIGLGAFHRAHQAVYIEklNRNQGGEWGICAVNIRSNSQLVDELKANGCRYHIAeqDSQNVELREINAIRDALFAGADK-EPLFEKLMSPKTKIVTLTVTEKGYYLAPADKTLRQDDPSIQHDIQNPTAPKTAPGILVEALYRRKDLGLPPFTILSCDNMPNNGSLTRRAVCELAAHRSAEFAQWIEDTVAFPSSMVDRIVPAMSDDSRERLQKELNCHDQNAVMCEAFSQWVVEDNFPQGRPDWEHDGVQMVKDVHPFETMKLRLLNGSHSLLAYVGLAAKYKTVAQAVADEKFAALIRHYMSVEAAPTLDLpeVKVHEYIESLISRFANDSLQHQLSQIAMDGSQKIPQRWLNGAEERLANdgDLNATALGVAAWLFYVRGEDLEGNQHKVDDPMAQALRELHGRcdPESLVREAFKLNDIFSTKLSQSEMFSSAVLSAYQLLISSGVTECL------
25 UniRef50_A6W5I3 Mannitol dehydrogenase doma... 503 1e-141 1 43.0% 1:486 18:508 LSLGTLDAVEAG-HRPRVDPRALGVGVVHLGIGAFHRAHQAVYTEDAVAAAGGDWGICGVTQRS-RSVVEQLGPQDGLYTVLAHDAGGSSARVVGAVRELLFAGEEP-GRLRALIAAPTTRLVTLTVTEKGYRHDPATGRLRRADPDVAADLDgaRPPRTVVGQLVAGLAARRAADAGPVTLLSCDNLPANGAVLRGLVGDFCAALPDglREWIAASVRFPSSMVDRIVPATTPADRDQVQRLLGLRDEGVVVTEPFRQWVVEDDFAAGRPAWERAGAVLTADVAPYEAMKLRLLNGSHSTLAYLGLLAGHEHVADAVADDGIAALVDRLMAHDVVPTLAVpgFDVARYRQDLLDRFANPALHHRTLQIAMDGSQKLPQRLLGTISDALAAGREPRAACLGVAAWMRYvtGRSEAGVALPVDDPLAARLGEVTAGAgpAAVVDALLGLPEVFGTDLPADARFRALVEEALEVLTRDGVAGAVRESV--
26 UniRef50_A1WNS1 Mannitol dehydrogenase, C-t... 497 1e-139 1 41.2% 1:486 4:509 LSPCTLARLPASVARPGYDRDALKTGIVHLGLGAFPRAHLAAVNEAALHagDLRWGIAGVSLRSPDT-RDALAPQGGLYTLALRDIDdtALQVIGCLRQCLVAAEDP-AAVIALIAHPDTRILSLTVTEKGYCHDPASGALQVQHPQVQHDLAALDRPCSTLGFIVAGLRQRRRLGLAPVTLLSLDNLPSNGHLLRALVLDFAARIDPALADWIAGRCSFPCSMVDRIVPRTTDDDRALVRAALGVEDAWPVVGERFLDWVLEDRFVAGRPAWERSGARLAQAAQPFETLKLRMVNASHSALAYLGLMAGFQTVDQAIAQPALRRYLERLMTEEIAPTLplAGLDLHAYRERLLARFANPALAHRTAQIALDGSQKLPQRLLGTVRDRLAAGASIELLALAVAAWLHHLRGRDEQGQPYRIHDPQADALAQQHahQATSAWVRTFSGLAPVFGTDLQHSQPFVHAVAAQLHALRTRGVLPTLEGLA--
27 UniRef50_C5PU77 Mannitol 2-dehydrogenase n=... 496 1e-139 1 34.4% 13:483 3:474 ------------VHTYNYDRNTIQSGILHIGVGNFHRAHQAFYTDQLLHDEDqqWGICGACLLPGdkLVQNLRSQQLDYTLTVCGREGedIYRIGSLSELLWAVEDQ-QELLHKIADSAIRIITLTITEGGYNLDKVTNEFMLDNEWIKDDLIHPANPTTVFGYIAEGLRQRKASGSGGITILSCDNLQHNGNTAKRAFCTFIAAQDPELAEWMETNVSFPNSMVDRITPATTAQDITRLNNQSGIYDKAPVYCEDFIQWVIEDNFIAGRPAWERVGVEFTDDVTAYENMKLSLLNASHTLLSYPSFLIGYRKVDEAMQDKEMVKFVCDFMDTDITPHVPPpgIDLKEYKQTLIERFANPAVSDQISRLCFDGISKFPVYIMPNLLKMIKDNQELSRVAFLIASYRHYLkqTDDKQQQFEIAEP---WLTAEDRESTKSNNPVDFLRLSAFRSTDLTAVASFVGLYTGFAHSIREKGLKKVLQ-----
28 UniRef50_B5ZVY4 Mannitol dehydrogenase doma... 496 1e-139 1 42.6% 5:476 7:479 ----TLSGLAPTAKLPAYDRSRLKSGILHLGPGAFFRAHFAPFTDGALAADGGDWGIEVASLRTAD-VADNLSAQNGLYTTLIRDTSGTTAEVIGSILKAHVAPRDP-AGLLARLEDPDIRIVSMTVTEKAYGFDPATGGLDLKHPDIVADLANRHAPRGVIGYLVEGLARRRQKGIAPFTPLSCDNLPSNGAVLKRLVLEFTSRIDADLHRWIEANVPFPSTMVDRITPASTDATYADAERLTGRTDMAAIETEPFTQWVIEDHFANGRPAWEKvgALMVEDVSAYEKMKLRMLNGAHSLLAYLGYIGGYEFIRDVMDDAALAALAYRHMHAAARTLDPVPGIDLDDYANELIARFANKAIAHRTYQIAMDGTQKLPQRLLEPACEALAHGDRAETFAIAVAAWMRYALGEHGNGERYELRDPRAAEIAALIAdrTGPAISAALFALPGLFPSALTGHRAWTQDVSDKLEILIQD------------
29 UniRef50_A9CFC2 Mannitol dehydrogenase n=1 ... 495 1e-138 1 37.6% 1:484 5:485 LSSLALSHLPQDVLLPTYDREAVTPGIVHLGVGAFHRAHQAVFIDDCLARGETGWGIVAASLRSPDT-RDAIAPQDNLYTFCLRDGENETLRIVGSILETIVAPEDP-ERLLRAMTDPRVRIVTLTVTEKGYLADLSAGTLLRDHPDVVHDLAHPQKPRSALGFLLEATRRRRVAGAVPLTLLSCDNLPSNGRILRRLLVEMAGLTDKDLAEFITENLSCPCVMVDRIVPATTATDRERVTVRLGCEDAWPVIAEPYFRWVIEDRFPHGRPGIELSGAEIVDDVEPYEHMKLRMLNGAHTAMAAIGQCSGLETIADIYADPRVRGYIDRYWREVGSTL--SPAVSGPDYVTGLRQRFANPALRHRAAQIASDASQKVPQRILAPLAELRAAGAPDAAALFAVALWIRSCATLNERGEAIVMADPaaEWAVPTGNGEEPDAVIDRFLTFRRVFGPEWLADEAFVTALRAAYRDIVQYGALGAIER----
30 UniRef50_Q3BME4 Mannitol dehydrogenase n=13... 494 1e-138 1 40.0% 1:473 24:490 LSRDTLATLPPVVSRPSYDPASPTIGIVHLGAGAFHRAHQAVYIDDLLAE-DPSWAISAVSLHRPQ-VRDALRPQHGLYTLALLD-EHPHLRVIGAIREVLCA-ADEHAAVLARLADPAVRLVTLTITEKGYCL--AGDTLDLSHPDIVHDIAHPARPRSAIGYLVAGLQQRRHDGTAPFTALSCDNLTDNGMLLQRAVVRLAEQTDPALAQWITQHAAFPRSMVDSITPATDDALRTRVHDQLGVHDAWPIQRERYSQWVIEDRFCNGRPAFERVGVTLSEDIAGYARAKLRLLNAPHSALAYLGSLLDLETVAEAMRHRELAAYVETLMRAEIAPTLqmQGFDAQRYSDAILARFRNPAIGHLLAQIAWDGSQKLPVRLLGTIGDALATGRPIQRLCLAVAAWLHFVRRQAHNG--VPLTDPLNDVLSAlnATGDAGHDVADFLTLEAVFGS-LPADARFRASLQAAYAAL---------------
31 UniRef50_D2U8Q2 Putative mannitol dehydroge... 494 1e-138 1 39.3% 1:486 5:484 LGSATLHTLPLAITRPSYALDRVRIGIVHLGAGAFHRAHQAVYLDDLL-ASEPDWAISAVSLHNPQ-VRDALCAQDGLYTLALLDA-QPELRVIGAIREVLCA-QDQQAAVLARLTDPAVRLVTLTVTEKGYCLTGE--HLDLAHPDIAHDLAAPHAPRSAIGYLVAGLRQRWRLRLAPYTVLSCDNLHDNGGKLRRAVLRFAHHIDPALAAWIEAEASFPRSMVDSITPASDAALRERIATQLGYDDAWPIQRERYSQWVIEDRFCNGRPAFERVGVTLSEDIGGFDRAKLRLLNGPHSALAYLGTLLALETVADAMCDTPLATFIETLMREDITPTLplSGFDPQRYIDAILTRFRNPAIAHKLAQIAWDGSQKLPVRLLGTLADALAAGHRIDRLCLPLAAWMHFVRH--QAHRDVPLIDPLQETLREiaAGSDDVQDVDAFLTLDTVFAP-LSKDRRFVDALQRAYASLGDGSAAETRETLV--
32 UniRef50_Q8NU38 Mannitol-1-phosphate/altron... 492 1e-138 1 37.7% 1:486 7:498 LNTENLQEIAsgVQIPAFNRADVAPGIVHFGVGGFHRAHQAMYLNELMNEGklDWGIIGMGVMPSdrMRDALASQDHLYTLTTKAPDGtdQKIIGSIIDYVFAPEDPARAV-ATLAQDSIRIVSLTVTEGGYNIDPATEDFDHTNPRIVADREALQalQTFFGLITAALISRKESGSTPFTIMSCDNIQGNGDLAKRFFLAFAHSVSSELGEWVENNVAFPNSMVDRITPETTDGDRDDIKE-IGYIDAWPVVSEDFTQWVLEDAFTQGRPAYEEVGVQVVSDVEPYELMKLRLLNASHQGLCYFGHLAGHHMVHDVMADTRFQDFLLAYMEREATPTLklPGVDLDAYRRQLIARFGNAAVKDTVPRLCAESSDRIPKWLLPVVRENLAAGRDVTLSAAIVASWARYAEGTDEQGNPIKIVDRLSERVQENASGNRTD--ILSFIRDRGIFG-DLVDAEPFTKAYSETLSSLHDRGAEATIDALL--
33 UniRef50_B9JJF8 D-mannonate oxidoreductase ... 492 1e-138 1 40.1% 8:473 10:467 -------QLHDPIESSTYDRPALKPGIVHIGLGAFHRAHQAVYTDTALAHAFGNWGIVGVSLRSTE-IAQDMRVQDCLYSVVACDRFGDSVRVVGSIVEALAANEDG-EAVLARLADPAIQIVTLTVSEKAYGIDPVNGGLDHAHAAIAQDLKSPTRPMGVIGYLTEGLARRLSAGLPPFTVLCCDNLPSNGRIVRRLVIEMAATRDPALAEWVSETVSFPCSMVDRIVPAATAETRARAEKLLGVEDRLSIEAETFSQWVIEEDFVGGRPAWEAGGALFVENVEPYEKMKLRLLNGSHSLIAYLGQLQKLEFVRDVMAIPENVALVRRHMQAAVRTLDPVPGIDLTHYMDQLVERFANPAIAHRTQQIAMDGSQKLPQRLFQPAVDAISSGSDAAEFAFATAVWIAYLK------QAETIDDPRGRELQRAAADATPADEAASFFAMAGLFPSELQANRAWRDQVNSLLRSL---------------
34 UniRef50_C8WEY9 Mannitol dehydrogenase doma... 492 1e-137 1 35.7% 1:485 13:503 LNEKALANlpKRVKIFKYDRSKVTAGIAHIGVGNFHRAHQARYIDDCLAIPGNewGIVGISLgsSKAKAKAMKDQDCLYTLTEYDAKgpSTRIIGSIIQYLHAPEDP-EATMAMLVDPAIRIVSMTITEGGYHLD-SEGNFQSDAEAVQADLKDPEHPKDTFGYIVEALARRRKAGTEPFTVFSCDNQRGNGDVAKQAVLSFARLRDPELAEWIEKNVSFPNSMVDRIAPTVTEEEAEAVRKLTGIDDQSPVIAENFLQWVIKDEFCNGRPPFEKVGAEFTQNVAPYEHMKGRMLNASHTAIALPGVVAGYEYVHEALGDPEIHRLVYDFMTKDVIPVTKGpgISLTDYRDMVLSRFSNPALKDQLVRIAGDSANKLPTFLLPTINEHTEdsRDLRRMAFILACFRRYLRGIDDKGHKFTPIEpiSKEERAEWGSENTEG----FLNCRILESLGLADNEAFVKAFNHAVSLLKPQGVLGALRHL---
35 UniRef50_C8SWP0 Mannitol dehydrogenase doma... 488 1e-136 1 34.9% 1:487 8:496 LGPALLDRLPVSVQTPAYDRAALAPGMAHLGVGAFHRCHQAEYTDDLLSLQFDRWGVVGINIRPP-SLAGTLGRQSGLYTRLIRENSHVEARVIGSIVKVVDSQESAKPAL-DVLASPDIDLVTMTVTEKGYCHIPSSGELDLGHPDIVHDLTNSQAPRSVPGILAQALEQRRATHGQPMTLLSCDNIPTNGVILEKVVRTFAERRDKGLADWIAANAAFPCAMVDRIAPAVTRDDLDSVEQWFGYRDDAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGAQTTLATLGVLAGLEHTFDAVADPLLLAFVRRMLIQETLPTlpVPGVLPLAYVEQSLGRLQNTAIRHRNHQIATDGSQKIVQRLLNPIRDRLRQGASIGLLSVPVAGWMAYlqASARFGKRWPVSDPYAGKVAGIAdgRDAPALASGILAIDGIFDPGLAANETFRAAVTSALDDLLSDDPMAAVRHSLE-
36 UniRef50_C8SUD3 Mannitol dehydrogenase doma... 487 1e-136 1 40.6% 1:485 15:504 LSATTLQALPASVATPSYDRGRITPGIVHLGVGAFHRAHQAAYVHDCLTAGETDWGIIGVSLRSPDT-RDALAPQDGLFTLAIRSSGEEELRVIGSIGSMLVAPEDP-GAVLAALSDPRTRIVTLTITEKAY-LRAAGGGLDAAHPDIVHDLANPQGPRTAHGFLTEALARRRAAGTPPFTVLCCDNLPANGATLHRLLIEFAELRDarLAGHIADEVAFPSSMVDRIVPATTDADRARIAVELGVEDAWPVMTEPFRQWVIEDNFSAGRPAWEKFGVTMVGDVAPYEDMKLRLLNGAHSGIAYLGLLSGHATVDRAFADPAIRQFVDALWA-EAIPTLPEdgLDTKTYTAELAERFSNTALAHRTAQIANDGSQKLPQRIVASAVECMEAGTEFVHLTLVVAAWIAACAARGKTLPEGHFTDPLDGPLTALLSEQLPaeTVTAVFDLAG-FAKDHAERQTLIGLVAVHLVHLRRDGPTLAFAAL---
37 UniRef50_A0R3S3 D-mannonate oxidoreductase ... 485 1e-135 1 36.1% 1:485 13:476 LSSSTLEQL--TIPHPSYDRAKVQIGIVHFGVGGFHRAHQAMYVDKLLEMGLaeWGICGVGLLANDrmAEVMEAQDGLYTLLLEHPDGheARVIGSIVDYRYAP-DDQEGVIELLAAPTTKIISMTITEGGYYIDSA--------PEI-----------NVFGLVTEALVRRRDRGIGSPTIVSCDNIEGNGDVARKAFTTYAERVHPGLGEWMSANTRFPNSMVDRITPVTTPEVISTVEREFGVADQWPVVAEPFTTWVLEDSFSDGRPPYEEVGVMVVDDVTPYELMKLRLLNASHQALCYFGYLAGYRLVHDAASDPLFADFLLAYMDSEATPTlpVPGIDLDEYKHTLIERFANPGVRDTIARLCYGSSDRIPKWLVPVIRENLKTGAPIRLSAAVVASWARYAEGVDEQGEPINVEDQLADTLVPIALSQR--EHPTAFIENTEVFG-DLASSQRFVDEYLWALDSLHRHGARATLESL---
38 UniRef50_P80354 Polyol:NADP oxidoreductase ... 482 1e-135 1 35.3% 1:482 2:483 ITRETLKSLPANVQAPPYDIDGIKPGIVHFGVGNFFRAHEAFYVEQILEHA-PDWAIVGVGLTGSDrkAEEFKAQDCLYSLTETAPSgsTVRVMGALRDYLLAPADP-EAVLKHLVDPAIRIVSMTITEGGYNINETTGAFDLENAAVKADLQNPEKPSTVFGYVVEALRRRRDAGGKAFTVMSCDNLRHNGNVARKAFLGYAKARDPELAKWIEENATFPNGMVDRITPTVSAEIAKKLNAASGLDDDLPLVAEDFHQWVLEDRFANGRPPLEKAGVQLVDDVTDWEHVKIRMLNAGHITLCFPGILVGYENVDDAIEDKDLRGNLENYLNKDVIPTLkpPGMTLEGYRDSVISRFSNKAMSDQTLRIASDGCSKIQVFWTETVRRAIECKRDLSRIAFGIASYLEMLRGRDEKGGTYESSEPTYGEAQKKLAKADDFESALKLPAFDG--WRDL-DTSELDQKVIALRKVIREKGVKAAI------
39 UniRef50_C6XQI5 Mannitol dehydrogenase doma... 482 1e-134 1 35.7% 1:488 9:486 LNPENISKLSSGVRCYDYDRDSLPVRVVHFGAGAFHRAHQLDYFDRLNAI-DPNWGVCSASLRSA-KVKDALEPQDGLYTLVVLD-DVIEYRIIGTLKSVVLA---KDPEFIERLTAPETLVVTLTITEKGYCVT-ADGQLDVENPDIKRDLATPSSPVSAIGWLALCLSIRMERGLNGLNIVSCDNLSGNGEKLRAAVLGYVQHTNPDLVSWIESNCFFPNTMVDSITPATDESLLGRVQDAIGLNDEWPIQREAFTSWIIERNVSEDFPDLAKVGVTFTSDVAAHESAKLRLLNGAHSSLAYIGLLCGHETVYKGMSDPDVMTFIASLMRDEIAPSVNVpgMDIEAYINSLISRFQNPEIEHLLSQIAWDGSQKLPFRLFQTVQDNIGAGRSISKLCMGICAWMEFVRRQAISGTQ--LVDPKDKELRALALASDGKNYAEKFIRESGVFPASLRENTIFLENINNSYASLA--GFKKNILTRVEL
40 UniRef50_Q15XM6 Mannitol dehydrogenase-like... 480 1e-134 1 36.6% 1:473 7:479 LNENSLEEAakGINVPQypPSAAKIGIVHIGPGAFFRAHQAWYTHQALKRHGGDWCISAVSLRSSG-VSDALTAQNGLYCLAELDKD-TNFEVVGSIKEVLVA-RQQYADVIARLIHVDTKFVTLTITEKGYCLN-NQGELDLAHADIQHDLKVMTERVSAVGILVEALSIRHDKGLPAFTVISCDNITGNGGKLKNALVSFAAQCNLTLATWLADSITCPSTMVDSITPATDDALRELVQQTLSIKDNWPIKREAFLQWVIEDCLPSDRPAWEQVGAVLTQDVEGFERAKLRLLNCPHSSIAYLGCLLGIETVYDAMQHTQLVAFIESMIQEEILPSIEGpeLDAKQYSQDILQRFRNPAIRHLLSQIAWDGSQKIPMRILPIIQQNLREGRSVRLLCYALAAWMQFVRLQFSKGE--TLVDPLAAQLETLCVSCNGEadVGLFLSMSAIFPLSLATDGDFNSGLQAAYTNL---------------
41 UniRef50_Q0AT70 Mannitol dehydrogenase n=3 ... 479 1e-133 1 36.9% 1:472 3:466 LNHSTLDHLPSLVRRPDYVPSQQACGIVHLGVGAFHRAHQAVYTDAAMNAGERNWRILGVSLR-TRSVHDQLIPQDGLYSVSTKSEAAPEVRVIGAIANVLVAPENPAAV-VAALASAATRVVTLTVTEKAY-HQSTGGGLDMNAPAVAADLSH-RGPTTIYGYLAAGLRGRWRESAGGLTLLSCDNMANNGKSLARSLNDFLELYDPALADWTRHNCSFPSSMVDRIVPATTDADRRALSETSGVEDSGAVFTEPFSQWIIEDSFVESRPGWEQHGAQLVNDVAPYETAKLRMLNGAHSALAYLGLARGLSLVSEAIADPQVGRLASRLMREEAATSfpAPGQDLRHYADELEARFSNPALPHRLIQIAMDGSQKIPQRWLDTLSARQETGRDCPAILQALASWILYVRGT-----SGEVDDPMRDQLARTWQSAGHTGIASALFGESGLFREHWSASETAIEHLNTHIRE----------------
42 UniRef50_Q98JL8 D-mannonate oxidoreductase ... 478 1e-133 1 36.5% 6:487 2:485 -----LDQLPAAVRTPGYDRTTLAPGMAHLGVGAFHRCHQAEYTDDLLARQFDRWGVVGINIRPP-TLADTLGRQSGLYTRLIRENSHIEARIIGSIVKVVDSQASAGPALT-VLSSRDIELVTMTVTEKGYCHIPSSGALDLGHPDIVHDLANPHAPRSVPGILARALELRRATHGRPLTLLSCDNIPANGVILETVVRSFAERRGNGLAEWIAANAAFPSAMVDRIAPAVTQHDLDSVEQWFGYRDAAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGTQTTLATLGVLAGLEHTSDAIADPLLSAFTRRMLVEETLPTlpVPGMDPSAYVEQSLGRLKNTAIRHRNHQIATDGSQKIVQRLLNPIRDRLRLGQTIGLLSVPVAGWMAYlqASDRFGKRWPVSDPYAGKVAEIAdgRDAPALASAILAIDTIFDPGLAANAAFRAAVTSALGELLSDDPMAAVRHGLE-
43 UniRef50_D1N0Y6 Mannitol dehydrogenase doma... 477 1e-133 1 33.3% 11:487 2:479 ----------NTVEKFKYDRRNVKAGIAHIGVGNFHRAHEEYYTDLLLEYPdhNWGICGIALLPSdkLVEALRGQRGEYTLTVCGRDgdQAFLIGSLVELLWSVEDP-GAVIAKLADPAIRIITMTITEGGYNLDKSTGEFILANEGVQHDLKHPAAPSTVFGFVAAGLRRRMESGGGPVTILSCDNLQHNGSTARRAFTAFFEAQDTALAGWVAANVTFPNSMVDRITPAVLPADRERLNASNGTDDAAPVYCEDFIQWVIEDKFAAGRPAWERVGVEFTGDVTAFENMKLSLLNASHTMLSYPAFLTGYRKVDDAMHDERFARYLRDFMDKDITPYVPAPgvNLDEYKQTLIERFGNRSVSDQLARLCFDGVSKIPVYIMPNLGKMLRDKADLTRVAFFAAAYRRYLkgTDDNGAPYTVDEplTEEDRKLIASADP----DVFLGLSPFASVDLRGDARFPVLYRKMVKELEEKGVSPVLEAVLR-
44 UniRef50_D0XNS1 Mannitol dehydrogenase doma... 470 1e-131 1 38.2% 1:482 6:480 LCRATLGSLPEGVAGLTYDPSRITAGIVHLGPGAFHRAHMAHYVHAQMSRGqmDWGIIGAGLTSFDavREALAPQDWLYTLVERDDQGASAQVVGSIVEVLPPV--GTGAILDAIDRPGIRIVSLTVSETGYCLDATTRRLDRTNPLIASDLAHPRQPGSVIGLLVEACRRRRDAGRPAFTALSCDNLPGNGGLLRAAVLEFAAQVDPGLGDWIATHARFPATMVDRITPVTRPEDVAMLTRTWGLNDGWPIVCEPYAQWVIEDDFADGRPDWEAVGVQFTADVAPYERMKLRLLNASHLALASLGWLRGHSMVAEAMRDPALERCIRALMETELSPTLPAdpVDLAAYQDRIVTRFSNRTLQDTVERINTDASINM---LLDPIRDRLADGRPIRRLSLAVAAWIRRLALIEDD--ALALRHPLADALTSLARGGATGE--AQILARSDVFG-DLSGNAAFLTAVTRRLRVMTTVRIPARV------
45 UniRef50_P33216 Mannitol 2-dehydrogenase n=... 469 1e-130 1 37.3% 12:486 4:475 -----------SVTRPSYDRKALTPGIVHIGVGNFHRAHQAVYLDDLFALggHDWAILGAGVRPTDamREALAAQDNLSTVIELDPAGHRARQVGAMVGFLPVEADN-AALIEAMSDPRIRIVSLTVTEGGYYVD-ASGAFDPTHPDIVADAAHPARPATAFGAILAALRARRDAGVTPFTVMSCDNLPGNGHVTRNAVVGLAELYDAELAGWVKAQVAFPNGMVDRITPATGPHER-ELAQGFGLADPVPVTCEPFRQWVIEDHFPAGRPALEKVGVTFTPHVHAYEAMKIRILNGGHAVIAYPSALMDIQLVHAAMAHPLIAAFLHKVEVEEILPHVPppDTSIPDYLTLIESRFSNPEIADTTRRLCLDGSNRQPKFIVPSLRDNLAAGTVPKGLVLLSALWCRYCFGTTDSGVVVEPNDPNWTALQD--RARRAKETPAEWLAMTEVYG-DLAQNDLLAAEFAAALEAVWRDGAEAVLRRFL--
46 UniRef50_A6TKR4 Mannitol dehydrogenase, C-t... 469 1e-130 1 23.6% 21:487 12:483 --------------------RNYPEKIVQFGEGNFLRAFADWTIDKMNKEANFNSGVVVIQPLQGG-LIDKLNDQDGLYTLYLNGIKDGEVvvIDCVTRGINTYTN-YDEYLAVAENPELRFMISNTTEAGITYNEQDRLED-------------RPQASFPGKLTALLYHRFksKDKGLVFIPCELIEKNGEKLKETVLKLAALWnnDFKVWIDEANTFCNSLVDRIVPGYPKERMEEIRQELGYDDDLVVEGEPFHLWVIEGPavKEAFPAHKVgvLVVDDMTPYRTRKVRILNGAHTSMVPVAYLYGIDTVRESVEDSVVGQFIKETIFEEIIPTLDLPREELDGFANDVLDRFRNPFIKHQLMSISLNSMSKFETRVLPSILEYerKGELPKKLTFSLAALIAFYKG-ERNGEKIALTDDAaeQYKTLWKAYEGKEdvTTILSNEKIWKMDLNQISGLTDMVTNYLSKIQEHGVKNVLQRMMK-
47 UniRef50_Q28N88 Mannitol dehydrogenase-like... 468 1e-130 1 33.7% 1:486 14:497 LRLDTLEALPHGIERPTYSRADLTPGIMHIGLGNFHRAHQAWYLHRLMQAGehDWAIIGAGVRAYDamRDRLAKQDYLTTLIELTPTSTSAEVIGPMIDYL-PIEDGNGALIAAMTDPAIRIVSLTVTEGGYYIDPATHGFDAAHPDMAHDAAHPDSPHTAFGAIIAALRARRDARAPAFTVQSCDNLQGNGAIVRQTVVGLARLGDADLADWIEANASFPNSMVDCIVPATGPAEIA-LARSFGIDDVAPVSHENYRQWVIEDAFCHGRPAWEKVGATLTDDVHSFEAMKIRLLNGGHQVIANVGELLSCETIADCMADPDIAAFFRKVEHDGIVPYVqvPGMTPPAYVELIERRFANSAIRDTTRRVAFDGSSRHTGFILPIVREALAAGGSVDALALVEALWARMCAGTREDGTMIAPNDPFWDDLHATAQAART--RPAAWLEQTHLYG-DLADHPAFAEAFTGWLSDIWSNGSRATIHRFI--
48 UniRef50_UPI0001AEC29A mannitol dehydrogenase doma... 468 1e-130 1 37.7% 15:475 1:464 --------------KPNYDLEATGCGIVHIGPGAFHRAHQAYYTEKALAYGG-DWRIHGVSMRSA-SLKEALSTQDNLYALCIVDNE-PETHIIGAIK-TLSTLAHDREDIVAALVNKQTKIVTLTVTEKGYCLN-AQGHLDTDHPDIKADLVTPETPVSAVGLIVQALAQRKQAGYADITIISCDNVSDNGKKLQKAVTEFANKTDESLGQWISENIAFPCTMVDSITPATEDSFKANVAAELGLTDNWPIQREAFTQWVVEDNFSGPRPAWDKVGVTFTHDVSFFEKAKLRILNGTHSTLAYIGLLLGKETVFDAMRTPAIKQLIQTMLKEEIVPSLSSDnfDLNAYAQDIVKRYENKHIRHLLSQIAWDGSQKIPFRILDTVRDNLKAKRNIDLLCSAVAAWCLFVNNKARLNE--TITDPLDSMLRATAKSVDFqeLAKKLLSLDTMF-AELSVNNTFKEKVLEKVNQLLD-------------
49 UniRef50_Q3JL86 Mannitol dehydrogenase fami... 464 1e-129 1 39.6% 1:487 13:497 LSSDHCRALPPEVSRPRYDRRALRTGIVHLGLGAFHRAHQACYTETLVERGDLRWGIAGVELRR-RHTVERLAAQDHLYSVTERAGDAARTRVVGAVHRTLFAPQ-ALATLLGLIADPSVSIVSLTVTEKGYYRRPGGGGLDLDDPAIRRDLAQPHAPSTTLGVLAAGI--RLRAAHAPLSVLSCDNMPSNGDTLRALLAQYAEQTDGALARRIRCDVAFPNTMVDRIVPAATPESLDWVQSRIGVRDEAAIVCEPFAQWVFEDRFAGARPRWEDAGALVAADVRPYEKMKLRLLNGSHSAIAYAGQLRGRRTVSDAMADPLIDALARGVMTRELLATLDVpgYDVRAYCASLIERFRNPALAHRTAQIATDGTQKVPLRWLPALAESAAAGVERPFLERALAMWLHYVeaRDESGRPLVLEDPGAQALAARLHGagATDAVRAALGL--IASRDAARWPelTARVGAHLETVRTRGTDALLRPLLD-
50 UniRef50_B8HDJ5 Mannitol dehydrogenase doma... 463 1e-129 1 38.2% 1:474 1:474 MERLSIAALAGTGHKVALQRDQLEPGIVHLGLGAFARAHTAVFtdAMLAADDPQWGIIGVTQRS-DAVARQLTPQDGLFTVDERGEGAAPARIVSSIVEAISG-RDNPDLVVERIAAPATKIVTLTITEKGYRFNPQTRNLDLDDAETIADL-GGRPPRTTVGQITRGLQQRCRTGAGPVTVVSCDNLPGNGELTGTLVRNFAEALpdDLLAWIAANVAFPSTMVDRMVPATTDGDLAAVERELGLRDEAAVVAEPFKQWVIEDNFAADRPRWEESGALFSNDVAAWESAKLRLLNASHSMLAYLGLAVGMETIADAVEVDAFRTACRSMMLEEALPSITLpgMDGEQYCDEVLRRFANPALGHTTAKVGSDGSQKVGLRLLTTVRGTLDAGREPKWAALAVAAWMHHVAG----APATELNDPLAKELQAVLPEDRTADTVvaLLGFRPVVEPYLAGHETFKALLLHWYRIID--------------
51 UniRef50_Q15PN7 Mannitol dehydrogenase ross... 462 1e-128 1 30.9% 1:486 6:484 LSISSMLNVADTVQKPNYALGAVLPSIVHFGAGNFHRAHQAAYCDALLNQGETRWGITGVSLRSA-KMRDNLAPQNCLYTLAILGEKETRFRVVGAIQNMAVGPENP-QALIDLLASEPTQLVTTTITEKGYYLK--NGVIDLESTDIANDLASLTAPKTTYGYLAAGLIKRASKGDSPITLLCCDNMNAGGERLRDGVHMLLAKHSPETVSWVNENVAFSASMVDRVTPATDELLKTEVAQELGVQDAAPVAAEPFTQWIIEDNFAGDRPPFDKVGALFVDDIAPFERVKLRFLNAGHSMLAALGYLVGDRFIHEALKRPTLAQFTEQALKLNVMPVTSVpgLQAEHYIAQVFARFRNGNLPYAALQVGTDSSQKIQQRWFPSIDDALKQSVDTRYLAFAVAAWVCFIHKALVRG---DLNDPLIDEFTNS-SSTGASSDVLAFLTLAGANKFSFFSDTGFMASVHGYHDYINGMGVEEAIVHCF--
52 UniRef50_A4ADC5 Mannitol dehydrogenase fami... 460 1e-128 1 34.5% 1:472 4:474 LNKDKLQRLPRALQPETYDRT-PKPKVVHLGVGAFHRAHQAWYFDRLNhePEYPWLIEGASLRS-KSAGEQLNPQDGLYVHVARSAAGSDVTVVQSLTQVVNAFEEP-EALTSAIARPDTQLVTLTITEKGYCQNGGNDDLDLHREDVKRDLVSLEHPCTAIGSLLAGLRRRYREKGQPLTILSCDNLSHNGDVTRRAVLAMAEHHEAGLTEWIGDNVSFPNSMVDRIAPAVTAADRDETQKLTGLEDHGLAITEQFSQWVIENNFKGQRPALERVGVTWVDNVDAWELRKLRLLNAAHTALACLGSWLDIRFVHEAISDPRLESLVDQMWRETATTLPDTEDFNLTTYLASLKLRFGNPHLQHALVQIATDSSQKLPQRILAPLAERLAQRDSVTALTTVVAAWLCIQTGQSQRGTDLGFSDPLSETLRRALNEAGDstQVDAVFAVYPALGA-LGEDDKWREQLIAAYAT----------------
53 UniRef50_B1K2W5 Mannitol dehydrogenase ross... 457 1e-127 1 37.0% 1:487 18:505 LANATLGRAAPHVAVPAYDRHRLTAGIAHIGVGNFHRAHQARYVDHVLHLPGHewAICGIGLGSGPakADALRAQDCLYTLTEFSSDGTtvRVIGAMIEYLHAPADP-EAVLTRLADPAIRILSLTITEGGYNLDETTGAFRFDTPDVAHDLLG-GPPRTAFGFIVEALRRRRAANVLPFTVMSCDNLRGNGDTARRAVLDFARATDVDLAAWIERYVAFPNSMVDRIAPQVTDAIRLRANRLSGFDDTAPVVAETFSQWVVEDSFSAGRPAFDAAGVELRDDVHAYESMKGRMLNASHMLLAYPAILLGHRFVHDAMADRDLAALLDIFLTRDVGSILTLpgVSARAYARDTLARFRNAALGDQLLRVAHDGASKIPVFHEKTIGALIARHGDMRREALLLACFQHYLKGVDDLGNAFAVSEP---QFEAADLERVRSGAPLAILDSKPFAPLGLASNAGFVELFRTMQAAVATRRTRDAIRLALD-
54 UniRef50_B7RYR8 Mannitol dehydrogenase ross... 457 1e-127 1 39.0% 1:482 4:474 LTKASLGELSVSVELPTYDRDSIEAGIVHLGIGAFQRAHQAVYTDQAMNLSGGNWGIIGVSLRS-DTVARQLLPQDCLYSVLSEGGVEQSLRLVGSVTQVLFAPT-QLDEVVSAIAAETTAIITLTITEKGYCTGPDGHSLDRSNPVIEADLAAPEAPRSAIGLLALGLRRRQSLGNSPVTVISCDNVAANGQVIACVLKEYTELAFPELSAWLQHNTSCPSSMVDRIVPASTEAQQLRQSQMLGLTDCSAIATERFSQWIIEDNFCSPRPDWRAAGVQYVENIAPYEEIKLRLLNASHSAIAYCGLLAGKEFVDQVVTDRQLGEFVETLMNDDLMPALNApdFDIEGYKSQLLARFRNPCLGHRCEQIAMDGSEKIGHRWLPVLQG----SGENSKLIVALAAWCYLVLYTD-----IAISDPKEAQLLQLRARRD-DSRLRELLACARVTQRTVTSVDSLCRQIEQKIDKLAQGGILALV------
55 UniRef50_B8H5V1 D-mannonate oxidoreductase ... 456 1e-127 1 40.4% 1:473 13:481 LNATSYPGVVPGVAIPTYDRDKLQIGVVHFGPGAFHRAHQAHYFDQLLAH-DPRWGVCAVSLKSPG-VRDALKPQDGLYTLAQLDAE-TTFRIVGSILEVLVAPEDPP-SVFARLAAPTTRLVTLTVTEKGYTL-SANGGLDESHPDIVHDLANPREPRSAVGYLVEGLRRRFAAGLAPYAVVACDNLADNGWRLKAAVVAYAAKLDESLAAWIDREGRFPRTMVDSITPATDDALRARTLAATGLEDAWPIQREAFAQWVVEDVLPADGPDLASVGVIMTDDVRGFERAKLRLLNGVHSTLAYVGILRGHETVFEAVSDPTLAALASDMMAKDIIPTLTPpgLDLQAYADAILGRFRNPEIRHLLAQIAWDGSQKLPFRILGTLTETLEAGRSIERLAVPLAAWMRFVALRAKAGEA--IVDPLQDRLLalAATGEASADVAAFLALDSVFPASLAGDPRFVSALEKAYADL---------------
56 UniRef50_Q97L67 Altronate oxidoreductase n=... 455 1e-126 1 24.0% 21:486 12:482 --------------------KKYPEKILQFGEGNFLRAFVDWQVDRMNKAADFNAGVVIVQPLE-QGLVDMLNEQDGLYTLYLQGLKEGKAvvIDCVTRGLNPYT-QYEEYLKLAENPEMEIVISNTTEAGIAFDE-------------NDKLGRTCQNSYPGKLTAFLYRRFKtkSKGMLIIPCELIDRNGEKLKATILKFAELWnkEFADWIEEANTFCCTLVDRIVPGYPRDTIEEVHAELGYEDSLVDVGEQFHLWVIEGPeiKDILPFEKAGvqVVKDVTPYRTRKVRILNGAHTALVPVAYLYGLDTVGHSVEDKVIGKYLTELVYDEIIPTLDLPEEELKYFAGAVLERFLNPFVNHYLMSIALNSMPKFETRDLPSLLEYKKrgQLPKKLVFSLAALIEFYKGKrdEDIKLADGEDILELYKDLWSKFDGTDavETVLGYEKNWKMNLNELEGLTDAVTENLIKIDKLGMKEAVKSVM--
57 UniRef50_A3HWR4 Tagaturonate reductase n=1 ... 455 1e-126 1 23.4% 11:475 2:466 ----------KTLSKSFVSRQERPVKILQFGNGNFLRGFTDYMVEEANEKGVFNGNIQVVQVHSP-VADPKMIEQDCLFHVLIRGLKEgeAKLITCIHGISNPNED-FNTYLKLAENPDLRFIISNTTESGIQFDS-------------TDINPDELPSSFPGKVAALLYRRfgDPSKGLIFIPCELIEDNGITLRTCIDQYASLwpKAFTEWLFSACTFCNTLVDRIVPGFPKDSIQEIQERIGFEDKLAVMAEPFHFWAIEGPevKEEFPLDRAgvLFVKDLTPFRTRKVRILNGGHTSMVPYAYLTGIRTVREAVEDPVIGKFMREVIFNEIIPTLDMPKDELEKFANDVLERFANPFIVHELKSIALNSISKFKVRVLPSLLEYYekNLWPEKLTLAFAALLVFYKG-EYKGVETPVNdsIMAEFKAAWELGSTKETVEKLLSERSYWGEDLREHEGLVEAVSKAVDELLQ-------------
58 UniRef50_C7MVR8 Mannitol-1-phosphate/altron... 455 1e-126 1 41.6% 10:475 10:448 ---------PATVEVPH--RPD-TVRILHLGPGAFHRAHQAVFTEDA----GGGWGICGVTQRSP-AVVDQLRPQDCLFTVVERSRTTTSCRVVGTIRDVLFARAEP-ERLRAYFTDPKVRIVSLTVTEKGYRPDSG-----------------------VIGQLVAGLEARRATSEAPITVLSCDNLTGNGTVVRSRVLEACARLpdSLASWITDHVRFPGTMVDRIVPATTDADRAEVRSVLGVTDEAAVVGEPFRQWVIEDDFAAGRPAWETVGAQLTDDVAPYEAVKLRVLNATHSLLAYRGALAGYDTIAEAVADPVLAEEAAEFMEHDVLPTLVVpdVDIAAYRRRVLERFANPALRHRTTQVAMDGSQKLPLRLLGTVRDRLAVGEVPIRAVRAVAAWMVYVagRDRDGRPLPLDDPLADRLRAAAGGAgpHAIVDGLLSVREVFGEDLPDHAALRAALVEAVADIAA-------------
59 UniRef50_C6PA78 Mannitol dehydrogenase doma... 454 1e-126 1 21.1% 19:487 10:483 ------------------DYKKYPEKVVQFGEGNFLRAFVDWMINEMNEKGVFNGSVVVVQPIQNG-LVNALNEQDGLYTLILQGIRDGKAevVNSISRGINPYSD-YETFLSVAESDSIRFVVSNTTEAGIAFDE-------------NDRFDITPHNSFPAKLTAFMYRRYkrSDRGLIVIPCELIDKNGLKLKEMILKYADYWNLefVDWVENDNVFCSTLVDRIVTGYPREDIDKIQEEIGYEDSLVDVGEIFHLWVIEGPkiEEEFPASKIgvKFVDDITPYRDRKVRILNGIHTTMVPVAYLYGIDTVKEAVEDEVVGKFIRDAAYEEIMPTLDLPEDEIKEFVKEVFDRFKNPYVKHYLTSIALNAMSKYETRVLPSLLEYirFGKLPKKLVFSLASYMEFYKG-NRGSETIPLSdpEILElkNLWKQYDGSYdvTEILAYDKIWKINLNDVEGLNTAVTEYLYSIEKNGIKESLKEVLK-
60 UniRef50_A6X6E4 Mannitol dehydrogenase doma... 454 1e-126 1 37.2% 4:484 5:482 ---SALVNDAAAASWPAYTPENHEVGIVHLGLGNFARAHLLSYTDTVLAQKGGDWRVTGVSLR-GTAVADSLNPQDGRYTLITRGP-VTEAHVIGALDRVLSGPTVGNDAL-DAMTSPGCRIVSLTVTEKGYGIT-SDGRLDREHPAIVADLANPDAPTSVIGLIVAALSRRMTGGLPPFTVLSCDNLSHNGQKLRDAVLAFADQTGGRLlrWIAEKVAFPSTMVDRITPASNAQTAKLAVELTGREDHAAVETEPFSQWVIEDKFCAGRPEWECAGALFVDNVAPYENMKLRMLNGTHSMLAYSGQLSDKSFVRDVMADPDHAVLVRRHLA-AAAATVEGLSIDLDAYAAVLVERFANPAIAHSTAQIAMDGTQKLPQRITTPALEALASGKPYGPFVFALAAWLAYLARKEDDGHPVPLNDPKATELQTGLKdkTPEEIIRAVAscPDILPSKLT-NGVFGSALRDTLHAIQSEGMPKVIKR----
61 UniRef50_UPI0001C35E41 altronate oxidoreductase n=... 453 1e-126 1 24.7% 11:487 7:496 ----------ETLEKQGYdlKDAPERVLQFGEGNFLRAFVDYFIDMMNEKADFNSKVVLCQPIAPG-LADMINEQEGLYTLFLRGFENgdKRVISCVSRCLNPYKD-YDAVLACAKNPDLRFIACNTTEAGITYDP-------------ACSFTDVPADSYPGKLTQFLYKRFEtpGKGFVILSCELIDNNGKELEKCVLQYAEKwgEEFTSWIKQENIFCSTLVDRIVTGYPRNEAASICEELGYQDNIIDTGEVFGFWVIEGPelKKELPFEKAgvLITDDHKPYKQRKVRILNGAHTSFVLGAYLAGQDIVRDCMEDEVICGFMNKTIYDEIIPTLTLPREELMSFAASVTERFKNPFIDHALLAISLNSTSKWKARVMPSLKGYIAngRLPECITASFAFYIAFYRGTepAGNEYTVKDDriLQFYYDHRNDDVKTLVHAVCVNEEFWGEDLSAIAGFEDAVAGYVAAIEEKGAYEVMKSCLD-
62 UniRef50_B5ZJL8 Mannitol dehydrogenase doma... 453 1e-126 1 37.2% 1:486 14:499 LDSSTLGHLPPAIIVPSYDRGAVRPGIAHLSVGNFHRAHQAVYIDRVLGQQdaGWGILGVGVMDdrAKAESLRAQDGLYTLTECPADadTVRVIGSIVEYLHAP-DDRAAAIRRLADPAIRIVSLTVTEGGYYVDES-GQFQIDHPTIAEDLA-RDVPHTVFGLATEALRLRRDSGAGPFTILSCDNLPHNGHVARTAFLSWARARDADLAAWVEAHVTFPCTMVDRITPAVRDPDIARLDAASGIADRAPVFCEDFIQWVVEDTFCAGRPPLEQVGVLFTGDVAPYERVKLRMLNASHSMLGLPGVLMGYRIVSDIMHNPDVIELLERYLGLDAEPLLqpPGMELHEYGALLLRRFRNQAISDQLLRIASDSASKLPVFVRDTAEGTLARGGDAARIAFLLACFAEYLRGRDDNGAAYSVTEPHLGPDDLTLAGDADSARA---LDMSVFAGWGLRDHPDFVALFVRTRAAIRAGGTRATLHTLV--
63 UniRef50_Q1GMX0 Fructuronate reductase n=3 ... 452 1e-125 1 41.6% 17:487 9:467 ----------------SYEQTLLKPRILHIGFGAFARAHPMVYLHHGLVAEGGDWGVVAARLNSGVDALDSLDAVQGRYHIAEADGDTITLREIGLLCGTCHPARDGVDAIPALIASPDMSVILLTITEKGYCTK--DGQLDLTQAAIQAELDG-GLPTTAIGVLVSGLERRRAADLGGITILSCDNQPDNGALTRAAVLGFAEELDLNLAEWIRTHVRFPSSMVDRIVPAMTDDSHTAVASALGRDDPNAVLCEPFRQWVIEDDFANERPPFAEGGAMLVADVQPFEEMKLRLLNGAHTTLAWLGQLLGYQTVADCMADKELRALIRHLMLAEQAATlpLEGIDLAAYADELLKRFENTRLRHRLDQIASDSSQKMPQRLFAPIAINLEAKREWSVSALAVAAWIKGL------GSLPPVPDPRQDELRRAALCNDP---VAAVLSLPSLVPDALRPLAEFQAAISVAFERL-QGGAKATVTTTAK-
64 UniRef50_D1F375 Mannitol dehydrogenase doma... 450 1e-125 1 48.3% 96:488 42:436 -----------------------------------------------------------------------------------------------AVSRISWSRRRTPQAVLDIMSHPDTRIVSLTITEKGYCRDAAVSGLDRSHPDIIYDLAHPATPRSALGFITEALRRRRAQGTAPFTVLSCDNLPANGETCKNVIVQFAGCTDTDLAHYIEETVAFPSTMVDRIVPATTDEDRISISRTLKVLDQWPITTEPFSQWVIEDRFPTGRPAWEIAGATFVQDVAAFELMKLRLLNGSHSTLAYLGFLAGHRTVSQTMAAPGFKQLIKALMEIEIAPTLplEGFDLSSYQAALIHRFENHALHHLTSQIAMDGSQKLPQRLLNTIQERLDGGGSIDLLALGVAAWMRYVTGKDEAGTPIDVRDPLSGQLLDQTQGkaPDEIMDALLSFRQIFTARLAANELFREKLRLALGSLYAVGSAETVRRYAEI
65 UniRef50_C6IZA9 Mannitol dehydrogenase n=6 ... 448 1e-124 1 24.8% 19:485 16:472 ------------------DLPAYPERMIQFGEGNFMRAFTAWQVQQMNKQGRFQGSVVMIKPQSS-PVSEHYAKQDHLYTVLINGIAEQQveINHSVSRLISPYTD-YEQFLALAEQDSLEFITSNTTEAGIAYNP-------------EDRLTDAPQRSFPGKLTALLYRRYQLGKAGFTIIPCELIDRNGEKLREIVLRYAAEWddGFIQWLERENTFCCSLVDRIVPGFPQQKAGQLEQQLGYQDRLMVTAEPYLLWVIEGPalPERLPLSEAgvIFTEDLRPYREQKVHLLNGPHTAMAALGLLAGLTTVEDVMNDEDLSVFVRELMEQEIVPMLDLPRSGLLSYAEAVRERFMNPFIRHELASISLNSIAKFQTRLLPVLLRYqeRGELPKRITLAFAALLVGYRGDRLVRKDSPEV---LALFDQAWSQ--PAEAIPALLRETKLWGEDLSSVPELADTLEQYVRKLDAFGARATLQWL---
66 UniRef50_Q65F24 Tagaturonate reductase (Alt... 447 1e-124 1 21.4% 20:487 11:480 -------------------KPSRPERILQIGEGNFMRGFIDWQIHRLNEETDFNGSAVVVPPRRGS--VTAFQEQDGLYTLYLEgrEGREVrvITSISRVVSSY-EHYDEFMELADLPDLRFVFSNTTEAGIIY-------------IEEDRLSDRPQKSYPGKLTALLYRRygSREKGLVILPCELLEDNGKILKDIVLRYTNAweQGFIDWLEEANVFCNTLVDRIVPGFPKENAHRLEEAAGYHDSLMVKAEPYHLFVIEGPklRDELPLHEAgvEFVQDVTPYRIRKVRILNGAHTAMTPVAYLAGLETVREAAEDELIGSFVKELIQREVLETIDMPDSELDNYVEEILDRFKNPFIRHKLIDISLNSFAKFKVRNLPVLMEYAErgKLPARTVFALSALIYFYRGqdDGAIPLSDDDEVLAFLKRLweETDVSNIAFHVLGFEKVWGQNLNDMPGLTDKTAEYLRDMKQTGMRKALEKMMK-
67 UniRef50_A0QWD8 Putative oxidoreductase Yei... 445 1e-123 1 38.1% 1:480 1:477 MNLLKLGSYGTAV-PPRPDPNALTVGQVHLGLGAFHRAHQAIYTEDAmhTGETHWAIAAFTQRSGAAATR-LRPQDGLYTVTERGAAASPPRVVGALREVGDGSADPT-AMVERICDPAVHVVTLTVTEKGYCLDPATGGLDFDHPRIADDL-HSGAPRTVPGVLAHAIARRARSGAGPLTVISCDNLPHNGRLLQQIVHEFSDAAGLSVDD--GATVTYPSTVVDRIVPATTDEDIAALSRSIGVRDQAPVMCEPFRQWVIESRFAGPVPAWSAVGTQLVDDVAPWEQLKLRVLNAAHSTLAYLGLRLGYRSIAEAVHDSVLADICRRLFADDVRPSLDApgLEVGDYGESVLARFANTALPHTTLQVASDGSQKIGPRLLRTVSARAGQGTPARWAALGIAGwlHVVDPVDADGQPTALADPRADELTAMTAGLPVGAAVRRLVTEPSIVGADVAQRRDFADYVVGVAEDLHRHGADA--------
68 UniRef50_A9KNI5 Mannitol dehydrogenase doma... 443 1e-123 1 22.2% 21:485 12:485 --------------------KDRPVKVLQFGEGNFLRGFVDYMIDVANEKEVFDGSVVVVKPIAFGNL-DMFHEQECQYTLSLRGKEDgeSRIVTCISDAVDAINE-FEKYESFAKCDTLRFIVSNTTEAGIVYDE-------------TDDFNALPPKTYPGKLTKFMFDRfgDESKGLIIIPCELIENNGPELKKCVLQFAKLWndEFVAWIENACIFCSTLVDRIVTGYPREEAETMCNEFGYKDNLICTGELFALWVIedKDISKELPLDKAgvIFTNNQKPYRERKVRILNGAHTSFVLASFLAGNDFVKESMEDDTVRKFMMSTVFDEIIPTLSLPKAECEEFANAVIERFENPFIKHALLSISLNSVSKWKSRCMPSLKGYVEknTLPKHLCFSLAALMSFYTGSerGEEEYTILDDaaLEFFAANSGKSSKEYANAYLSNEKFFGQDLTKIEGLVDAVASYVEDIRTNGMRKAMENL---
69 UniRef50_Q9KFI7 Altronate oxidoreductase n=... 443 1e-123 1 23.8% 17:486 16:500 ----------------RYKSSQLPERVLQFGEGNFLRGFIDWMIQQMNKQNVFNGRVVAIQPTPHGKVVPKLQEQDSLYTVWLRGIADGEteVITSISRGLNPYTN-WQDVLEVAASPDISVVFSNTTEAGLTYLEEGYDK-------------EKAPLSFPGKLAACLWHRYEteGSGLVIIPCELVEQNGKVLKELVCRYAKAWnqEFFTWLERENEFCHTLVDRIVPGFPSDTADECFERLGYEDILLTVAEPYHLFIIEGSevRKLLPFNEAGLHvwNHLEKHRNMKVRVLNGTHTFMFALSYLSGVDTVGEAMADEQLCSFIRKGLFEEIIPCVDAPEQEVTAFAETVLERFENPFLQHRLTDIGLNAVNKFRTRLMPTFNDYVAqgEAPTYLLFSLAALINYYRGVEEDgdSYLIRDDliEAFKVGWQQVNTGKLSLalLSKRELWGVDLSMERKVVDKVAESLQIIVEKGMRQAISGVL--
70 UniRef50_B7AP03 Putative uncharacterized pr... 442 1e-122 1 23.2% 22:486 13:496 ---------------------DRPVKVMQFGEGNFLRAFVDYIFDVTNEKTDFNGGVVIVKPIEFGNL-DRFHDQECQYTLQLRGFENGQprVITSVVDAVAAIED-YDKYMEYGLCDTLRFIVSNTTEAGIVFDE-------------TDKFDAMPPKTYPGKLTKLLYERYkaKDKGIILIPCELIADNGIELKKCIDKFIDLWndGFKKWIDEACSFCPTLVDRIVPGYPRDEAEELCKEFGYEDQLIDTAETFGLWVIESdqLRKELPFEKAgvVFTKDHHPYKERKVRILNGSHTSFVLASYLAGNDIVKQSMDDPTIRKYMEETLFNEVIPTLSLPEDECKTFANAVIERFQNPFVKHKLLDISLNSVSKWEARCLPSFLGYvkFGKLPKYLTFSIAALMSFYSTtdRNGEKYNIRDDqlDFFIE-NSTKSPKEFAQAYLSNTKFfgKDLSKVDGLVETVAEYITDIRERGMRAVVTDLV--
71 UniRef50_Q125C8 Mannitol dehydrogenase-like... 440 1e-122 1 34.4% 1:485 4:469 LNQATLTQlpSPVQLPRYRRTDARVGVVHLGLGAFHRAHQAMVFDALLQRGDPRWGVLGVAMRTTE-LADALTAQDGLYAVQVASREALRWQVVGSVLQACVAAREP-AQVVAAMAAPGTRWVTLTVTEKGYG-------------------------PALAALLVQGLAARRAAGLGGLTIASCDNLSDNGRKLQQLCVD-AAQHDAALAQWIDTACAFPNSMVDRIVPAATAQHRSDAAQALGLADACALGTEEFWEWVIERRFVDDADGDAlvGVQVVADVKPFEEAKLRMLNGSHTAIALIGAVLGVPTVADCIARPDIHRFVRSLMTEVVMPHLQRPG--LPAYRDALLARFANPELRHKVHQIATDSSLKIPLRWQATVLAQLAANGSIEPLALAAAVWMRYLLGADEQGQAYAISDPLGQALQATAQRrdVAGTVRALLAVSSIWGEVLPHDVRWTARVEHWLQVIRRQGVAAALAQL---
72 UniRef50_A9QSF6 Altronate oxidoreductase n=... 440 1e-122 1 24.2% 19:485 10:468 ------------------NKENYPVKVIQFGEGNFLRAFIEWQIQQMNNKGLFKGSVAVVQPIECG-MIDCLEEQNNNYTVVLEGLLEGKkeIISVIDCTINPYKD-FEDYLKLADIESVEFIFSNTTEAGITYD-------------ANDKLGDKPAKTYPAKLTQLLHRRFKNGMSGFQIIPCELIEHNGVNLKKIVLQYAQLWneEFVAWINAENNFYSTLVDRIVPGFPHDNKEEVFARIGYEDNMLVKAEAFLLFVIEGNklEELLPLKKAgvIVTDDMQPYRERKVRLLNGPHTTMTPLALLAGVETVGDVMKDDDFSQFINDEMYDEISPMIALPKDELTMYIEAIKERFNNPFVRHELTSIALNSISKCEYRLLPTIIQNIErgKIPKRITLAFSAWL-YIYGF--YGQTTVEPQDTSDVMATLEEMKKSNDYVTAVLGHEAFWGTDLTKYPELVAQVKQNIEDIQKIGTCALVQKI---
73 UniRef50_C7JI68 D-mannonate oxidoreductase ... 438 1e-121 1 32.9% 1:487 3:492 LNRNAISHVPDTVYTPRYDPALLRPGIVHLGCGNFHRGHQVVATQAAIDAEGRdwGIVSATMRRPD-LATVLQSQDNLYTLLTREPANTVASVMAAITEAVYAG-DDNANLAARIADPATAIVTLTVTASGYYL-SADGRLDPTFEAIQADLTAIT-PRTAPGIIAAGLAQVRQRGGVPPVILCCDNVNSNGATLRQAVIDLAALKGDDlaAWIETNVQFPDTMVDRIVPTATPDDIADACRLLgiEDRAPISAEPWFQWVI-GEFDGPRPRwaHPGTKFVSDVGVFERAKLQMLNGTHMLLAYVGALANLNTVSEAASDDALGRIAARFMRNEQTADVSLDTDELDRYTVDLMQRFRNPGIVHEVTRIGRNGSAKMASRIVQPMRSNIEAGRPVDGAVLLIASWIRWFALHEQDEFDIALTDPRAETLRGLCADARDdaQAEAFLAMEEVFGAPLPDHGKQVEAIASMLRRLTEESVPELLRTIAH-
74 UniRef50_C7G7K8 Altronate oxidoreductase n=... 435 1e-120 1 22.6% 22:486 49:522 ---------------------ERPVKVLQFGEGNFLRAFVDYMIDIANEQGKFNGDIVLVKPIEFGSL-DRFHDQECQYTVQLRGIVDGEprIVTSVADAVDAYGE-YQKYADYAKLDSLRYIVSNTTEAGIVYDD-------------TDRLEMEPPKSYPGKLTKFLYERYkaMDKGLVMLPVELIDDNGIHLKECVEKLAVLWneGFKTWLDEACVFTSTLVDRIVTGYPRDEAEELCKEFGYQDNLIVTGEPFALWVIeaKDISKEFPLPDAgvIFTDNQKPYKQRKVRILNGAHTSFVLASYLCGNDIVLESMQDELIFNFMKATIFDEVIPTLTLPKQDLIDFAEAVITRFNNPYVKHALLSISLNSVSKWRARCMPSFLEYIKngKLPTHLTFSLAALMAFYTGTerDGTEYQILDDAAveFFAANSSKDAAEYTHAVLSNEHFWGEDLTKLAGVEEAVTGYMEDIRALGMRAAMEKTF--
75 UniRef50_A5FZM9 Mannitol dehydrogenase ross... 435 1e-120 1 35.1% 1:485 11:465 LYPARLASLPADIARPGYDRDAVRTGILHLGPGAFHRAHQAAFTEDCLAAGETAWGILGASLRSAGT-RDALAPQDFLYTLALREGGREALRVVGAL-RGILAGADAPRAVLAALDDPAIRIVTLTITERGYGCDVARGELDEGDADVAHDLAAPDapRSVPGLLAASLWRRRRAGIAPFTLLSCDNLAGNGRVLHAAVTRMAARRDRGFGDFVAAEVACPSSMVDRIVPATTAEDRARIAARLGCADAAPVVGEPFAEWVIEDRFPTGRPGWERAGARFVTDVAPHERRKLRLLNGAHTMLATIGPGLGCATVAEAVAHERLSPVLARFWAEMAATL--PAETDAAAYCARLRARFGNTALRHELAQIALGSAQKLPQRILLPCLERWRAGRASPVLIAVIAAWLR---GAAAGG------DPLDG------------------LARREVFAADEWRAPPLRGMIAEECGAMARQGLAARLDAL---
76 UniRef50_D1PT81 Altronate oxidoreductase n=... 434 1e-120 1 22.1% 8:486 2:493 -------NHLQALNKRTAPKGNMPERIIQFGEGNFLRAFVDWIIYNMNQKTDFNSSVVVVQPIE-RGMVDWLNGQDGLYHVNLQGKENGQPvrVDVISRALNPYTQN-QAFMALAEQPEMRFIISNTTEAGIAFDD-------------NCKLSDAPASSYPGKLVQLLFHRYkcPSKGMIIMPCELIFLNGHHLKNCIFKYIELWKDdfKEWFTKYCYVCATLVDRIVPGFPRDTIKEIQEKICYKDNLVVKAENFHLWVIEkdELKAEFPAHKAgvLITDNEKPYHERKVTLLNGPHTVLSPVTYLSGVDIVRDACEHPVLGKYIHKVQFDELMQTLDLPMDELQQFAADVLERFENPFVDHQVTSIMLNSFPKYETRDLPGVKIYLQrgELPKGLVFGLAAIITYYkgKQADGAPISPNDdiMDRLTELWATGDTQKIAEGVLAFDYIWKEDLNqvPGLTALVKTYLDLIQDKGMLEAVKTIL--
77 UniRef50_A5V7I0 Mannitol dehydrogenase, C-t... 433 1e-120 1 37.5% 2:486 9:482 -PRLSAATVPEGVAPLRYARDRARSGIVHLGLGAFHRAHQAVYTDDAMAAGDAGWGIVGVSLRSP-AVRDALVPQDCLYIVEERGAPGGR-HLVGSINDALVAP-EAPERVIAALADPAVHVATLTVTEKGYHRDPRTNGLLVDAPDVAHDLAGGGDPRTVFGFLAAALDRRAAQGAGPLTILSCDNLPDNGRLLGGLLDDyaARRGARPGGWTS-----PSSMVDRIVPAITADDLAR----LPVEDRALTVCEPFRQWVIEDRFAGPRPRWEAGGAQIVDDVRPFELAKLRLLNGAHSALAYWGLPLGHAHVHEAVCDPDLLAFVRRQLLAEAAPSLPPsaLDPAAYVETILRRFDNPALPHRLAQIAMDGSQKLPQRWLATIVERAATGLASPAHLRSVAAWLAFV--GDASGGGRPADDPLASRLETIWDgaTPADIAAAIVRSSGVFPAAFGADEALVGALGAALAERLSKGPRAMLRDFL--
78 UniRef50_Q5WKX0 Altronate oxidoreductase n=... 433 1e-119 1 23.4% 23:487 30:506 ----------------------LPERIIQFGEGNFLRGFVDWMIHTLNKKGLFNGSIVAIQPTPHGKVVPKLNAQDGLYTLAQRgtEVDEREIVTSISRGINPYTD-WQKVLEVAENIDVRFMFSNTTEAGLTY-------------LQEEYAMERSPLSFPGKVAAYLYHRFqaKEAGMILFPCELLDNNGQLLKEIVIRLATEwpPSFIDWVDQHNQFCNTLVDRIVTGFPREGIEQFNQELGYEDTLLTTCEPFHLFAIekPEIAAQLPFEKAGLNvwKPVAPFRELKVRILNGAHTMMFAAAYLSGLDTVKEAMEDEELQQFIRTGVYEEILPLLQANEEEKIRFADATFERFSNPFNQHKLLDISLNSIFKWKTRILPSFLEAvkNNALPAALTFSLAALYVFYRPDhrGDTVYPIRENesIQILSDHNGEDLQRTIHAFLSNQQLWETDLTAVPQLAETVTFHVQNIGEHGMKAALRSFME-
79 UniRef50_C3Q0M1 Altronate oxidoreductase n=... 432 1e-119 1 23.1% 11:486 2:479 ----------KALNKETAAKTQRPERIIQFGEGNFLRAFVDWIIYNMNEKTDFNSSVVVVQPIE-KGMVDMLNAQDCLYHVNLQGLDKGQVvkIDVISRALNPYSQN-DEFMKLAEQPEMRFVISNTTEAGIAFDP-------------ACKLDDAPASSYPGKLTQLLYHRYKtkSKGLIIFPCELIFLNGHKLKETIYQYIELWneDFKQWFEEACGVYATLVDRIVPGFPRKDIAAIKEKLQYDDNLVVQAEIFHLWVIEAPqiAKEFPADKAgvLFVPSEAPYHERKVTLLNGPHTVLSPVAYLSGINIVREACEHEVVGKYIHKVMFDELMETLNLPKEELKKFAEDVLERFNNPFVDHQVTSIMLNSFPKYETRDLPGLKVYLErgELPKGLVLGLAAIITYYkgVRADGAEIVPNDaiMNLLKELWATGCTQKVAEGVLAAESIWGENLNNIPGLTAAVKADLDSIQEKGMLETVKGIL--
80 UniRef50_C6X1L4 Altronate oxidoreductase n=... 432 1e-119 1 23.6% 14:479 7:478 -------------TKPRLNREalPVKILQFGEGNFLRAFVDYAFQALNNELGFNAGVAVVQPLPGG-MVGMLEEQDGIYTVFLNGIKNgeVHLIDNIVQCINPYTD-FQALLDVAREESLEFIISNTTEAGIEF-------------VDTDVLSDESPKSFPAKVAAVLYERYThrSKGLTIIPCELINYNADTLKTVLLQYHELweDDFAAWINEACTFHNTLVDRIVPGYPKDEEAEFQNKLEYHDKFMVTAEPFFLWVIedEKLKEKLPFDKTnvKIVADMQPYRDRKVRILNGIHTAMVPFSVMYGNETVQETVGDPFTMKYVSEIAFNEILPTLNMDKDELNKFTEEVLDRFRNPFIRHQLSDIALNSISKFKVRVLPTIVEYfkYQKLPVNLVFGFACLIRFYKGS-WNGKILPVKDsiIAAFDAAWINTSLEGTVSEILENTEFWGEDLNQISGLSAAIVYAIENAEEHGIE---------
81 UniRef50_A0M230 Altronate oxidoreductase n=... 432 1e-119 1 23.3% 22:485 23:492 ---------------------EYPERVLQFGGGNFLRAFCDWMINELNEKTGFDAGVIVVKPTEGGN-YKELKQQDGLFHVAlrGEMLSEVKLISCVNRVIHSYNE-WDKYLKTALQPEIRFIISNTTEAGIKFSDS-------------DSFEDQPPKEFPAKLTLWLLYRFdaEDKGCIVLPCELIEDNGEELLKTVLQYIKLWddDFQQWIEKHNYFCSTLVDRIVSGFPENRKNEIQQKTGFKDPLLVAGEEYHSWIIKAPEikKELPFEKTnvQFVDELASYRELKVRILNGAHTSLVPVGYLAGLRTVRESMDDDLVLNHVEQVLREEIKPTlkFPESEIDAFIDAVLDRFKNPTLKHYLLAISLNSTSKFQARLLPAFKEYteKGHFPKRTAFSLACMLRFYKGEFK-GESIEVKDdvLSFFNQQWEKKdtEEFVESILQNKIIFGEDLTQFEGLVRTIAVYLNEIEAEGIRESLRNL---
82 UniRef50_Q0SCZ3 Fructuronate reductase n=3 ... 432 1e-119 1 34.8% 25:481 25:488 ------------------------TGIVHLGLGNFHRAHQAVYTALAMEREPGPWGILGVASRSS-TVADAMNAQDLLYGVVEISPDGSRVSVPGSHTGTLVAEQDP-ESVVRAIADPATKIVTITVTEHGYTVSPETGSLDLDSDAVRRDLREVRTPRTTIGQIARGLALRASTHAAPVTILSCDNLLSNGRQTEKLVREfaPTLRDDLLSWMDSSVTFPNSMVDRIVPSGSDRYNETALAHLGVRDTIAVPAEPFTMWVMEERFAAGRPAWEHGGALFTDDVEPYELMKVRLLNGTHSLIACLGALDGRATIPESVAQPFVEAAARRILCDEYLPTVTVPevDTDDYIRQLFSRWSNTALGHRTSQVGSDGSVKLAQRIPIPALEHLRRGTVPQYLSLTVAAYLCCIagFDPGPHARSMTDPARARLAGMADnaSTTEFVRSVFVDGGLFPSTLASHTEFVSRIADFVDIIVRHGPAVA-------
83 UniRef50_B7N4U6 Altronate oxidoreductase n=... 432 1e-119 1 21.3% 11:485 2:482 ----------KTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIET-SFPPSLSTQDGLYTTIIRGLNesDARLIRSVNREISVYSE-YDEFLKLAHNPEMRFVFSNTTEAGISYH-------------AGDKFDDAPAVSYPAKLTRLLFERfgALDKGWIIIPCELIDYNGDALRELVLRYAQEwpEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKseLRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKagTLPARLTFALAALIAFYRG-ERNGETYPVQDDalERYQQLWSQhgTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDVILEKGMREAVRPL---
84 UniRef50_D2PZ27 Mannitol dehydrogenase doma... 431 1e-119 1 39.6% 1:475 1:460 MNRLSLTNLPT---KPAVEPGGLSVGIVHLGIGAFHRAHQAVFTERAAQlgDSRWGISGVTQRSA-AVRDQLAPQDGLYSVLTRGGGAASIEVIGSVREVLAASEDP-AAVVQRIADPRVGVVTLTVTEKGYRAR-SGGGLDLTDPEIQADLTG-RPPRTVVGQLAAGLARR---SGAPLTVLSCDNLVANGPYLARLVREYAEAAG--LAGEQFEAAAFPASMVDRIVPATTDADRDEAARLLGVRDEAVVVAEPFIQWVIEDAFAAEQPAWDAAGAVLTADVAPWEQAKLRMLNATHSMLAYLGALRGYETIAEAVRDEDLATAATELMRVDVVPTLTPpgLDLTAYGESVLERFANPALKHRTAQVAMDGSVKLPVRLLGTVQDRLAAGAEPYAAALAVAAWMVYVSRTA------GLDDPQAARLqaAASAGGPAALVDALLAVDTVFAPNLRENKTFRSLLVDHVTALTR-------------
85 UniRef50_A6L4U5 Altronate oxidoreductase n=... 431 1e-119 1 22.9% 11:486 2:479 ----------KALNKETAAKTQRPERIIQFGEGNFLRAFVDWIIYNMNEKTDFNSSVVVVQPIE-KGMVDMLNAQDCLYHVNLQGLDKGQVvkIDVISRALNPYSQN-DEFMKLAEQPEMRFVISNTTEAGIAFDP-------------ACKLDDAPASSYPGKLTQLLYHRYKtkSKGLIIFPCELIFLNGHKLKETIYQYIDLWneDFKQWFEEACGVYATLVDRIVPGFPRKDIAAIKEKLQYDDNLVVQAEIFHLWVIEAPqvAKEFPADKAgvLFVPSEAPYHERKVTLLNGPHTVLSPVAYLSGINIVREACEHEVVGKYIHKVMFDELMETLNLPKEELKKFAEDVLERFNNPFVDHQVTSIMLNSFPKYETRDLPGLKVYLErgELPKGLVLGLAAIITYYkgVRADGAEIVPNDaiMNLLKELWATGCTQKVAEGVLAAESIWGENLNNIPGLTAAVKADLDSIQEKGMLETVKGIL--
86 UniRef50_C7H488 Altronate oxidoreductase n=... 429 1e-118 1 23.2% 17:486 16:504 ----------------GYILKDAPVKVMQFGEGNFLRAFVDYFYDIANEKAGYNGKVKLVQPIGnpQMADWINEQEGLYTLYLRGSEKGQkrVISCVSDCVCPYIDgwDEVLALARSEDLETVVSNTTEAGIAYTQGDSEFD------------QVPPNSFPAKLTRVLYERYKaaDKGLVILSCELIDNNGKELKKCCNNYAKDWnaEFIDWMNNANTFCSTLVDRIVPGrdPKELAAMEEANGYHDQVLDVGEVFGVWVIEGPalEDKLPFKKAGVNvvPDVTPYKKRKVRILNGAHTGFVLGAYLAGFDIVRDCMHNDTVRGFMNKMLHEEIIPTLPLDKKDLEEFASAVEDRFNNPFVNHELMSISLNSTSKWKARNMPSFLAYieQKQLPKCLTMSLAAYIAFYscKRPAGNTYKIQDDAWadFYYAHKDDTDAQLVHAVLTNTQMWDQDLTKIEGLEAAVLADLELIRTQGAEAAYKSCL--
87 UniRef50_C4Z5Q0 Tagaturonate reductase n=1 ... 428 1e-118 1 22.2% 22:486 13:497 ---------------------DRPVKVMQFGEGNFLRAFVDYIFDVTNEKTDFNGGVVIVKPIEFGTL-ERFHDQECQYTLQLRGFVDGEprQITSVVDAVAAIED-YDKYIEYGTSETLRFIVSNTTEAGIVFDETDND------------PNARPPKTYPGKLTQLLYKRYqaADKGLILLPCELIADNGIELKKCIMKFIELWgdGFKDWVNNYCSFCPTLVDRIVPGYPREDAAKLCEEWGYEDQLIDRAEVFGLWVVESdqLEKELPFKEAgvVFTNDHHPYKERKVRILNGSHTSFVLASFLAGNDNVENSMKDPVIRKYMEETLYNEVIPTLSLSKEDCEEFAKAVIDRFLNPFVDHRLLSISLNSVSKWEARCLPSFLGYVKknKLPKYLTFSIAALMSFYTSQTenGEEYNITDDKAvdFFRDNSGKSAKEFTHAYLSNTKFfgEDLSKVLNLEEVITEYITDIRERGMRAVVNDLA--
88 UniRef50_D1N830 Mannitol dehydrogenase doma... 428 1e-118 1 21.7% 19:487 23:501 ------------------PREEYPVKVMQFGEGNFLRAFIDWMIDKSNEAGRFGGMVQLVQPLP-QGMADFINEQDGLYTLILRGMENGakRVVTCVKGCLKTDSE-WDKVVECACLPSLELVFSNTTEAGIEYRPEAYT-------------PGKAQQTYPAKLASLLYERFKAGRKGLVIVPCELIDRNGAKLRECILHYAADwgGGFVKYVENECAFLNTLVDRIVAGYPRAEAAAYCEKLGYEDKLLDCGELFHLFVIedEKFRKVIPFAEAGlvWTSNQTPYRSRKVRFLNGGHTSSVLAAYLAGFDFVDKMTADPLFGRYLRTALFDEVFPTVQLPDGEKKAFAESIIDRFLNPFANHQLISISLNSISKWQVRVLPSLLDYVekGRLPKVLTFSFAALLAFYRGtkRAAGSYPISDDDaaAYAELDRSGDYRSFIETIASKTDFWGRDLNQVPGFTDAAAAYLKSIEDDGVAAAVRKLLE-
89 UniRef50_Q097G0 Polyol:NADP oxidoreductase ... 428 1e-118 1 37.2% 68:486 1:416 -------------------------------------------------------------------MAAAMKRQDGLYTVSEMAPDGttSRVVEAMVEYLYA-QDNPRAVLDRLSQPDIRIVSLTITEGGYLIDE-RGQFNLKHPSVVYDLEHPGEPRSAFGYIVEALDRRRKAGIKPFTVMSCDNLRHNGVQARRACVAFAKAKDPELAAWIEREVGFPNAMVDRITPATDNATRQKLRDLTGVDDAAPVICEDFIQWVLEDDFRNGRPEWDAVGVMITPDVSPYEEAKIRLLNATHTMLSYPAYLAGFRKVDDVLHDELFTQYLRDFLNLDAGYWLklPGLEIDAYKAKLLQRFGNRAVGDQVARLCMDGGSKISGFLLPTLHEILKHGRPYHRIAFFLASYERYLKGKDERGEAYPIVEPNARQLLERVIQSSS---PSTLLELTEVVGTQLPAHPGFVALYLQLRQKIDTQGVVATLKEIV--
90 UniRef50_A4QGN7 Putative uncharacterized pr... 425 1e-117 1 35.0% 20:473 13:449 -------------------PDAPPVRLVHLGLGAFHRAHQVWYTQKA----DPTWGYASFTGRSA-RMSDALTPQDGLYTLVTRSGEGDSPELISSLVEAQPAA--NVERLVELMADPQVAVVTLTITEAGYHL-AADGSLDEAHEDVASDLEALaeLKTAAGKLVKGLAARKTAEAGGIAIMSCDNIADNGALTSGAVLGLAAKVSPELAAWVKDNVTFPSTSIDRITPATEDSLIADVEAQTGFHDNAPVVTEPFASWIIEGEFPAGRPNWENAGVEFVSDIEQFERRKLWLLNGSHSLMAYFGQLRGHATVADAINDSVVRSHVEALW-DEAANHLTAEGLNVPGYRQSLIERFENPRIVHNLAQIAIDGATKQRMRAVPILKAELAAGRPGNGAALSIAAWIAYVLGTEE------VRDTRSAEINEAKLLDD------AILGLITVLDEDLATNDAIVTHIKKVVSEL---------------
91 UniRef50_C0CKL6 Putative uncharacterized pr... 424 1e-117 1 22.9% 21:487 20:495 --------------------RDVPEKILQFGEGNFLRGFVEDFVDQLNQKTDFCGKIVMVQPIMQGS-SDKINAQDGLYTLYLRGIQDgeRRIIQSVQRCIDPYRE-WESFLECAKNEELEFIVTNTTEQGIRYDP-------------ACEFGDCPQSSFPGKLTRFLYERftAGdkGFQILSCELIENNGTELKKCVLAYAKQWgqKFIRWIEEANTFCNTLVDRIVTGYPMGESERLNRENGYEDKLIDTAEVFGFWVIEGPelNEKLKLDEVniHICRDHIPYKKRKVRILNGAHTSMVMAAYLMGYEIVRDCMEDGLICRYVEEFLSTEVIPTIDLPREDLQNFSIAVIERFKNPFIDHRLLAISLNSVSKWRTRVLPTVLEFQKRFGYVPLIafSFAALLQFYRgaYREGTPYYVCD--SEDILGFFSQNSseDYAYQIAKSSWLWGRDLSLIPGFLPLVVKSLEKICDRGMRGAMDWILE-
92 UniRef50_UPI00016C06FB altronate oxidoreductase n=... 423 1e-117 1 24.7% 21:485 12:477 --------------------TSYPERILQFGEGNFLRAFADWMVELANEQGVYQGRIVVCQPI-AKGLGDLLNSQNCLYNVLLQGAT-EQLQTIHSISRVINPYED-YDAFSQLAQNPDLDVIISNTTESGIAYVP-------------EDTLADAPPKSFPAKVCAFLYYRYKhpDKGMLLLPVELIDNNGEKLKQIVIRYAKEWgeEFVEWIEKHNEFASTLVDRIVPGYPRLEIDSITEKLGYEDKAVVACEAFNLWVIedSKYKNRLPIHeaNVLWTDDVTPYKKRKVRILNGSHTAVVPLAFLAGFNTVLEFFRDTQFGGFEKDLINDEIIPATDMSQEELRSFADSVLERFNNPHIVHNLIDITLNNSSKFGARCIPTIVDYikFGTCPKHFAFAIAGFIRFYkgYRDNGESYKIKDDIaeLFANIWKNNTIEVVVHETLAN--FWEVDLADD--FEADVLAYLQAMLKDGVAEAMKQF---
93 UniRef50_A5FC00 Tagaturonate reductase n=2 ... 423 1e-116 1 21.4% 21:487 13:479 --------------------NRLPIKIVQFGEGNFLRAFVEYAIQKLNQKADFNAGIAVVQPID-KGLVNMINAQDGLYTlvKKGEEIQEKELITNIVKAVDPYA-SFQEYLSLAKEEELAFIISNTTEAGIEY-------------IASDLPTMTPPVSFPAKLTVLLNERFkaADKGLTIIPCELINYNADTLKEIVFKYSADwgAEFESWLTNSCSWHNTLVDRIVPGYPKDQIEEYNAQLSYKDDLIVSAETFFLWVIedDKLKAKLPFDKTdvKIISDMQPYRTRKVRILNGAHTAMVPFSLLYGNETVKETVDNEFTGGFINKALFEEINETLNMDKAELAGFSEEILDRFRNPFVKHLLSSIALNSISKFKVRVLPSLTGYVdhGKLPVHLTFAFAALIRFYKGT-WNGQSLPVNddIVTFFDGLWKSDDYEKIARLTLQNKNFWDEDLTEISGLTRAITIALEEIDANGIEAGFAKFQE-
94 UniRef50_A6VU92 Mannitol dehydrogenase doma... 422 1e-116 1 26.8% 2:472 3:470 -NYLQASSNREQLSVQDYSKEMIEAGIVHLGVGAFHRAHQAVYIDRLlhDGQQNWGITGVNIRPQDSQAFafVEQKGEYVLKTMAADGDtyEHIRSIVQQIDGAQEP-EKVDSTLADAKTQLVTSTVTEGGYYLDE-NRRLMLEHPAIKADITGARN--TLYAFLYAGLKLRSETSKTKITLLCCDNLRHNGELLETGLMQFLEAkdSALAQWVRQNVSFPCSMVDRITPKPSQKHVDEVRSRFGIDDHMTVMGEDFIQWVVEDKFAGKKPSLDLVGVQFVQDVVPFEEAKIRILNAGHTCVTYQAALKGLTYFDEAMRDEELKQYFTDFILQDSIPAIGDSVVDLPAYFDIIAQRFSNANIGDTVERICTDGYAKFPIFVFPTLEGAYRNGRIPKKTIQGIAGWFVFIQLSNQGKLKTPYHEPNKASLTAF---SNDEAGIQAFATDRFLWGNVPTEYPDFVTELTKAIKT----------------
95 UniRef50_D1BAE2 Mannitol-1-phosphate/altron... 422 1e-116 1 38.4% 8:476 26:544 -------SQRSGVTGPAVDPSAVTVGIVHLGIGAFHRAHQAVFtdAAAAAGETGWGILGVTQRST-AVVDQLVPQDGLYGVRTVGKDSSSLRLVGSVRGVAFPGEE-TQRVLDAIAAPTTHVVTLTVTEKGYR-AGADGRLDLGDRDVLADLedAVPARSAIGLLVRGLAARARAGGEPLTVLTCDNLLDNGHVLEGLvlDAAAGLpeRLRAWLRASVTFPCTMVDRIVPATTEGDRAAAEEATGVRDEGLVVAEPFMQWVIEDRFAGPRPAWELAGATLTDDVAPFERAKLRMLNGTHSLLAYLGSIAGHRLIADAVADPELLAAARSLLVDDVTPTLVApgLDLATYAESLLERFANPALGHTTIQVAMDGSKKLPIRFLATAADRLADGAVPDAVAHGVAGWVVFVagRTVAGEPLRLDDPIADELRAAAAEVaaEALVRRMLAVEQVFPAEVRDHAGFRDAVVAHTERLLAG------------
96 UniRef50_C5EW18 Altronate oxidoreductase n=... 422 1e-116 1 21.7% 21:486 8:449 --------------------NNVKETVIQFGEGGFLRGFVDYFFHKLQEKGLYDGKIVVVQPIE-KGMCQMLADQNCEYNLFLRGIDNGEVvhVTSISRALNPYT-QYEEYIALAESPDLRVLVSNTTEAGIEYLGTEKLSDM-------------PPKSYPAKLCQFLYKRYKAGLKGLILLPCELIDDNGDNLKKCVLQYADLWedGFKNWLETDNDFCSTLVDRIVTGYPRDEVEELTKKIGYEDKLIDTAEIFHLWVIGGHH-EDELPFQKAgvVWTDDVHPYKKRKVRILNGGHTSMVLGAYLYGLETVGECMKDEKVSSFLKKCIFEEIIPTIGDTE-DNRKFGAAVLERFSNPFIKHLLLSIALNSVSKFQVRVLPTILEYKEkgKYPAALTFSMAALISFYR-TDKANDG--------EEILAFMKTAS----VEDIMKREDYWHEDLSEMIP---MVQEYYDLIQDKGMAEAYSVVL--
97 UniRef50_A7MPR2 Altronate oxidoreductase n=... 421 1e-116 1 21.7% 11:485 2:482 ----------KTLNRRDFPGALWPERIIQFGEGNFLRAFIDWQVDLLNEHTDLNAGVVVVRPIASD-FPPSLSTQDGLYTTIIRGLNesESRLIRSVNREISVYA-QYDEFLKLAHNPDIRFVFSNTTEAGISYH-------------AGDQFDDAPAVSYPAKLTRLLFERfgAQDKGWVIIPCELIDYNGEALRELVLRYAHEwpAAFTTWLESANSFCSTLVDRIVTGYPRDEVAQLEESLGYHDAFLDTAEHFYLFVIQGPQWLArlRLDKlnVLIVDDIKPYKARKVAILNGAHTALVPVAFLAGLNTVGEAMNDAQICAFVERAIHDEIIPVLDLPRNELESFADAVVSRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQAqgTLPPRLTFALAALIAFYRG-ERNGEGYPLQDDalARFEQLWTQRGdrELVDAVLSDCEHWEQDLTAVPGLAAQVTRDLDAILNQGMRHAVAPL---
98 UniRef50_C6DKE8 Altronate oxidoreductase n=... 420 1e-116 1 22.7% 11:485 2:487 ----------QTLNRRNFPGRQHPDRVIQFGEGNFLRAFVDWQLDLLNEHTDLDAGIVIVRPIDSD-FPPALDTQDGLYTTIIRGLNEqePRLIRSVNREINVYR-QFDEYLALAHDPNIRFVFSNTTEAGISYH-------------ADDSLSDAPPVSFPAKLTRLLYERfgAADKGWVLLPCELIDYNGVALKELVLRYAAQwtPTFTAWLNDHNTFCSTLVDRIVTGYPRAEVEALQQEMGYQDTFWDTAEHFYLFVIQGPqlAEELRLNKlnVRIVDDIKPYKERKVAILNGAHTALVPVAFLAGLDTVGESMDDALIGKFVEKTIAEEIVPVLDLPHDELTSFAQAVLSRFRNPFIQHQLLSISLNGMTKFRTRILPQLLTYRERHGepARLTFALAALIAFYRGErdTLQTYPLQDDalERYSTLWAgvSLAELVNVVLRDADHWEQDLTQVPGLAAQVTEQLQTIVERGMRAAVEGY---
99 UniRef50_B7GPP4 Mannitol dehydrogenase, C-t... 416 1e-115 1 30.0% 11:473 11:458 ----------PRLNRAEHGRAAAPVRIIHLGIGNFTRAHQAWYTEHAPDTA--QWGIAGFTGRS-RRMVDKLAPQDNVYTLITSAPEGDSFEVISSISSMHEGG--DMAALHKYFADPNVSIVTSTVTEAGYKRN-AHGDLDVNDTDVSEDlvNVSELATVPARIVAGLEARRAANAGAITILPCDNLAGNGAAFRRVVEQAIEAVDPTLLEWTRDNVAWATSMVDRITPATTDAELQTVAQDEGWYDVAPVRTEPFLEWVIRGDFPKGRPAWDKAGAVITDDVEPYEQRKLWMLNGSHSTLAYVGPLFGHESVAEAIADPQLRAWVNEWWDLAGSYL----SVSSDDYRAKLLERFSNPRIHHHLFQIATDGSQKLPVRIVPVAKHALADGRDITAPARAVAAWIVFLRRF----GNTEAKDVNLDEVRKLAVNDDVTPAV-------SYLDKDLGANATFTNKVSELVNEL---------------
100 UniRef50_C2H7R3 Tagaturonate reductase n=11... 416 1e-115 1 23.4% 20:485 11:466 -------------------KNEAPVKVLQFGEGNFMRGFVDWQIQQLNNQQLFKGNVAIIQPLE-QGLGNMMNQQDNLYTVILQGLSNGEieIITIVEQMINPYHE-WDAYLSLAENDDLAYIVSNTTEAGIQF-------------VETDERTDTPPQSFPSKLTAFLYRRFELNKAGFTIIPCELIDRNGERLKEIILRYAEKWdpAFIEWLEKENVFCCSLVDRIVPGYPREDADVFNQRHNYEDQLMVKAEPFMLWVIEGPklENQLRFKQAgvIITDDMTPYRERKVHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFDLELIPMLSLPKDELAIYADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYieKNQVPPLISVSLAALLLMYRG--DQVKPYD-DEKTISEFVDAWSDN--ETAILRLLQNAALWGEDLSQLPNVADTVQEMATKIDQKGVRAVLQEM---
101 UniRef50_D1BXN9 Mannitol dehydrogenase doma... 416 1e-114 1 35.1% 1:464 6:482 LRLGAGTPLPDGVLAPPVVPTGV--GIVHLGWGAFHRAHQALYTQEAMAagDLSWGILGDVERTPQ-LVPALREQDGRYTVLSVGLEGGELvvVASVLDVAYPG-DETPRLLAAMAAPTTHLITLTVTEKGYCRT-GDGHLDLGQAQPDVDAFVAepAATAMGLLVRGLAARFLGEGTPVTVLSCDNMAHNGKVLKRIVDEFIAAAGPafSAWLAASTTWPSSMVDRITPAVTPATLDRVEEILGARDEAAISGEPFRQWVIEDSFAAPRPQWELVGADLTDDVAPWEEAKLRMLNGTHSLIAYSGRLFGYATMAEAVVAPEIADHARAYMFEDALPSVTPpgADLPAYGEGLLERFANPATGHSTRQVSTDGTQKIPFRWGGALQFALSNGRVPQGIAFGLAAWSEFVRRAVRDG--VDLGDPAGTEALTAvhGNDVEGVARGLLALPGVLPGGAGNHPELAD------------------------
102 UniRef50_A0JS82 Mannitol dehydrogenase n=3 ... 415 1e-114 1 36.7% 14:468 5:454 -------------QAPVLNRALMpvRIVHLGLGAFHRSHEAWYTQHAGD--GAEWGIAAFTGRRPDA-ARALAAQDGLFTLIERSGDGDSFEVIGSITEAVDGA--DLGRLRELVSAPATAMVTLTITEAAYGLAP-DGSFHAGAPEIAEDLAMLakPRTPLGRLVSALAGRRDAGSGPIAVVSCDNLSGNGDVARRAVTGMAEAWDSELALWIGENVSFVSTSVDRITPRTTDADIAEVEQACGYRDSTPVVAEPFRDWVISGDFPKGRPRWEDAGAVVVDDIEPYENRKLWLLNGAHSLLAYSGQLRGHTTVAQALEDPACRDAVEAFW-DEAAAHLRGDDLHIPEYRDALRGRFGNGRIAHHLSQIAADGTTKLRMRALPVLAAERSEGRSGAGSALMLAAWIDFVAVHKE------LQDPMSDAI-GTANGARGPERVASLLNLIS---PQLGGDPQIVALVAG--------------------
103 UniRef50_A7Z3M8 UxaB n=2 Tax=Bacillus RepID... 414 1e-114 1 20.3% 22:485 14:473 ---------------------QYPEKVLQFGEGNFLRAFADWQIDQLNQLTDFNGSVVAVQPRGSEKIKR-LNEQDGLFTLFLQGIKDgeHTIVKSISRGIDLFSD-YDSFKRLAAQEELRFIISNTTEAGITFEKGDRLED-------------RPQKTFPGKLAAFLYFRYKaaEKGCIMLPCELVEENGRKLKAAVLQYAGLWepDFTQWIHDANIFCNTLVDRIVPGFPVDTAEELTDFLGYEDRLLVVGEHYYLWVIEGpqLQNELPFAEAgaLITSDLTSYRTKKVRILNGAHTALAPVALLYGLQTVREAAEHEVTGRFIEELINEEILPVLQMEGV--TQYAADVLQRFKNPYIQHYLQSITLNAAAKFKTRNLPTLKAYIEqgRLPEKLVFSFSAMIyyWNGPNKPADGEGV----LNRFQMARSRCKDdqAASSILGEERLWGKNLNHLPGLTERTAFFLSVIHKRGMKHALHEC---
104 UniRef50_C1FJR8 Predicted protein n=4 Tax=M... 413 1e-114 1 31.5% 14:486 68:566 -------------RPPAVDRAACKSGMMHIGVGGFHRSHQQAFMNELLDVNFdnWCTTGVGVMPNdaMRDYLRDNDWTYPIVARSGTDaeVEEVYALRDMILAFEDPI-ACIEAMANPDVKIVSLTITEFGYrlNSSDFKFIERALNGEMDCETPYPepSTFGIICAAAAARFERGQRPFTLMSCDNLPHNGDVCKGRMTSAAEEllDEFVVWLQNEVRYPSTMVDRITPATSWDDIATMPDKYGFEDKWPVMCEPYKHWVIEDDFVDgrPPWETVGATLTKDVVSHELMKVRLLNVTHSAMCYVGILAGLTHVHEACLHSKIRSYLELVMLEEIAPTlaNPEMdiPSYARSVLERFENVAVKDQLDRIAMDGSEKFRVQGSGVIREGIALGLPMDAFALYVAAWAHFVKREVEAG--VEVKDMGAQGVTAPFRPGGTG--LPAFLDMVDIFG-DLAMDLTWRQNVTRMYDTINEHGMEFALDVVL--
105 UniRef50_A9VD39 Predicted protein n=1 Tax=M... 412 1e-113 1 31.1% 10:475 2:463 ---------AVELQRIKYARDQVQAGIVHLGVGAFHRAHQAVYWDTLLPE-DPRWGVCGINLRAADRafEALQAQGGLYTLKTLAFDgtEYRQVGAIVELIDASRD-YGAAVARAADDHIQIISMTVTESGYYLDEAD-VLRTQAPDVAQGLA-QQPTSCVYTYLHGAMRARMAGNGRPITLMSCDNLRENGHKLRTGFLQYLKAadEATRAWVEAHVSFPCSMVDRITPRLDPAHARDVRERFGIEDQVTIMAEPYIRWVIEDNFAGARPPLDRAGAIITRDVQAHEEAKIRVLNGGHTALAYLAALRGHRTFDRAMTDPELADFFMAYETEEVIPGLGESPIDLAAYRDEICARFSNASIGDTVARICSDGASKMPIFIRPTAEATARRGLVPHHAIRIMASWYVFMRAVQRGGedFAYVEPSWDTLVPLLAAGQE----TTFATHELLWG-DLPqcPTFVECLVAEIAKQEQ-------------
106 UniRef50_B9Y6P1 Putative uncharacterized pr... 412 1e-113 1 20.7% 11:484 3:474 ----------ESLNRQNHPRPQRPVRILQFGEGNFLRAFVDDFISQLNEKTDFNGSVCVVQPRPHGR-VKSLMEQDGLYTLLLEGKKEgeMRIIDVIEQGIDPYTD-YPALLQRAADPQCRVIISNTTEAGITYTDELVTLDV-------------CPQSFPGKVLAVLKHRFQtlESGMDLVCCELIERNGDTLKEIVCRKAREQGeaFLDWIENANRFYNTLVDRIVPGYPKAQAAALEDQLGYHDAYLVKGEIYHSWVIqdPVLHSVLPLDqqNIIFTDDLAPYRDRKVAILNGAHTAMVPLGLLGGLETVKETVEDPQIRRFLEAFLKEEVWPSLNFSESELVAFTHDVFERFENPDIRHELMSISLNSIAKFNTRDLPAMRHYYdhKALAPHACFSLAALIVLLGQRKSDGTPLISESPEVLACWQDWDENQPQATVDALIQL-PLWEGQLASMDNIAERLVQIIHSIATLGLRDALKK----
107 UniRef50_C6D022 Mannitol dehydrogenase doma... 409 1e-112 1 20.4% 1:475 8:500 LPSLNYASLREG-EASSYNrkSYPVKVLQIGEGNFLRGFVDWMIHRCNEQGLFNGSIAVSQPRpgAAKLKELKEQDGLYYQWIRGLHEGEleLISVFSDFIDPYQE-WERFLAQAANPGLELVVSNTTEAGLVYQASEWAPD-------------QPILSYPGKLTLLLYRRFEhsGKGLLLLPCELVERNGDKLRDIVLQHASDwpEAFAVWIREHNRFLNSLVDRIVTGFPAEEANERYTEWGITDRLLNAAEPYHIWAIEGekLDERLPFVKAgvVWTNDLQSYQLRKVRILNGAHTWMAAYGLLNGLNEVREVVEHPMYGAHLREVVFNEIVPSVPLPEAEMKIYAEQVIERFANPYVRHKLTDIAMNSLSKFKVRLLPTLMAYYErgDLPPYIVTAFASLLKLYrgSRLDGSQLLIRDDAaaELASLWNKADnkELLEDILGRDSWWGIDLNGIAGLSDRLTAEFAHLEE-------------
108 UniRef50_C6XUU7 Mannitol dehydrogenase doma... 408 1e-112 1 27.3% 1:487 4:492 LNNNLSDRVAKEIKVPAALKSS-RSQILHIGVGGFHRSHQVYAIQQlnPEKFSKWAITGVCMMPEdqLVENLRKQNQRYCLKMSTPSGTeiRVMNAIASILHSASDAV-KIVNRIASAETKVISFTITEGGYNIDFDKSRFLIENPAVQADLINPDQPGTVFGFLAKGLALRKLRNNGPITLMSCDNIQENGHILKLALLSFISVYDESLLPWIADNVRFPNSMVDRITPVATEKDKADFERQYGLRDNCLVVSEDYFQWVLEDNKYGDFPPLEQVGVEIVAEVKPYEAMKLSILNGGHTLVGLLGDALGYNRIHNAVVDEAISRIYDMYVQQEVIPTLAvdGVSFYNYYEKVKLRFSNAMINDSTDRIISGSSDKVPKFVLPVLQEQLKNSSPKKDITLliIAWWVYLEKEFNKNQMADVKDQKVTEWLPMFETAKGNG--DWFISYKPVFGA-LAEHVELVNLYKAYMKVVQEGELGSLIDKILE-
109 UniRef50_A8RNV1 Putative uncharacterized pr... 406 1e-111 1 21.5% 22:486 2:442 ---------------------ARKETVIQFGEGGFLRGFADYFFQKMQDKGLFDGSVVIVQPIE-KGMCSVLEQQGCEYNLFLRGIDNGQVvhIDIISRCVNPY-DDFEAYMKLAENPDFRFIVSNTTEAGIEYVDSNQFTD-------------APARSFPGKLTQLLYKRYRLGLKGFIILSCELIDHNGEELEKCCLRYAKQwgEEFETWLVRENDFCSTLVDRIVTGFPRDEHEELCRRIGEQDNMMDTAEIFHLWVIQGSH-EDELPLQKAgvVWTDNVDPYKKRKVRILNGAHTSMVLGAHLYGLKTVGECLKDEKVSALLRKCIFREIIPAIGDTE-DNRKFGEAVLERFSNPFIRHMLLSIALNSVSKFRARVLPTILEYRdfGSCPQGLTFSLAALMAFYR-TDDANDSQEIMDFM------------KTAPVEDILKREDYWGQDLS---PLLADVKKWYELIETEGMDKAYDAVL--
110 UniRef50_A3PQL9 Mannitol dehydrogenase, C-t... 406 1e-111 1 33.5% 25:486 4:456 ------------------------PTILHLSPGAFHRAHQAVYAEALIRAGHPEAGIRDVCLFPP-LIGAAHAAQGGTYHVLLRDQTREDLRRITAIREVLDRPHPDM------LCDPALRLVTMTLTEKGYCHVPGTERLDP--AAVAQDLADPQHPRTALGWLALALVRRRAAGLPGITLASCDNIPVNGRLLEAVLTAYVAEAFPDLLDWMAANVTFPVSMVDRIVPRVDAAAAESLAALAGAPDALGVVAEPFGQWVIEDRFALPIPPLDKVGVQIVADVAPFERMKHRILNGAQTAIAHLGALSGFATSFDAASDPVMGVWLERFCAAQARTLACPPGEDLAAYCRATMERLRNPHIRHPLTQIGTDSSFKLGQRIVEAAEHHL-DGPEARLYALTIAAWMRYNTGRDAAGRPIPVEDPLAPVFrdLAAGGDPSALVAGYLQLD-LFEGPLRQNEPFRRRLVALCTALETRTPRDIILASL--
111 UniRef50_C6WS61 Mannitol dehydrogenase doma... 405 1e-111 1 35.5% 1:479 7:474 LGLAALDRLPAH-ARPAADPRELPTRALHLGLGAFHRAHQAVYTEHA-----GGWGIAAIAPRSRD-VVAALRAQDCLYSVVERSPERPSARVVGSITEALHA-TDDADRVRALLTAPETSVITLTVTEKAHHRRADGRGLDLAAPEIAADLTSP-APSTVVGRLAAGLALRHRTTGAPVNVVSCDNIADNGAVLAGLVRDYAEAAnaAFLAWLDTAVAFPSTVVDRIVPATTEDDRATAARALGLRDEATVAGEPYRQWVLQDAFTADRPAWERDGALLVPDVRPYQVTKLRLLNGSHSALAHLGAAAGCTTIREVLHTAWGERFVRAFCA-EVAPTLPEGGPDPAGYADDLVTRFRNPAVRHLLRQIGSDSSLKVPERWLDPLRALDRA----PLLELALAGWVASTRPGDDDLPVHGTTDPLSDELAACWHDRPAHPELVARL-LRLVGAPDLAERTDLTTAVAQRLPALRAGRVE---------
112 UniRef50_UPI000178868B Mannitol dehydrogenase doma... 403 1e-111 1 20.8% 22:474 32:500 ---------------------DFPVKVLQIGEGNFLRGFFDWMIYECNRQGLFQGSVAVSQPRPGGrkLEQLRDQEGIYGLLTRGLQDgeEQWIPVFSKIVDPYAE-WENFLRIAELDSLDIIVSNTTEAG--LDYQRSEWNPDEPVL-----------SYPGKLTMLLYRRYksPDKGLMILPCELLERNGDILRSIVLRHAQDWgpAFQSWVAEHNLFLNSLVDRIVTGYP-EEAERYFDKWGHQDRLLNTAEPYYFWAIedPSLESRLPLRSAgvSWVSDLTPYQVRKVRILNGTHTLMASIGLLHGLNEVKEMTESPEWGDLIRNAMLEEIVPGVPLPPEEVAAYAETVWERFGNPFIRHRLQDIAMNSMSKFRVRVLPSLKEYIrhNELPSTITLGLASLIRLyyGTRLDGEELPLRddNLMTLQQAWQKVDGGelVASILGNQRIWGEDLNRIPALHETVSSYIEEME--------------
113 UniRef50_D2QL58 Mannitol dehydrogenase doma... 402 1e-110 1 23.2% 1:487 4:512 LSITTLAThpTAISLPPAHVQRLPERVLQFGTGVLLRGLPDYLIDRANRQGIFNGRIVVVKSTDGGDMT-AFARQDNLYTLCIRGIENGQTviCSAISRVLSA-KQQWDEILHLAASPDLQIVISNTTEVGIQLT--------------QDSIQLSPPDSFPGKLLAVLYARYKalNKGLVIVPTELIPDNGTALAAILRELanELGSEFIHWLETANTCCNSLVDRIVPGHPDatRKALTEELGYEDDLLTISEVYRLWAIDVPAGSDelSFHQAdvFIQPDIDLFRELKLRLLNGTHTLSCGLAFLGGFTTVREGMEDEQLSAFVSRVMLTDLIPGIPYPIDEAVafGMQVLDRFRNPFIEHRWLGITMQYSAKMKMRIIPVLLHHYeqPATPQYIALGFAAYLLFMRGveRAGEAYPINDSQADYFAGLWAGLSPAALVDTTLKNTDLWGTDLSRLPGFAEAVSHNLLQLLEQGATATLAARID-
114 UniRef50_C6W4F6 Mannitol dehydrogenase doma... 400 1e-110 1 22.8% 1:487 4:502 LFRENLRQLRNQPAVVVADDsqLPEKVLQFGTGAFLRGLADYFIDKANRQGVFNGRIVVVKSTDQGDT-KAFERQDNLYTICSRGIQDGEAkiSSAISRVLSAKT-QWSLVLDLAKNPAVGIVISNTTETGIQL--------------VQDDIYQWPPVSFPGKLLAFLYARygSADSGVVIIPTELIAENGKKLESIILELAHrlEVAFIDWIEQCNFFCNSLVDRIVPGKPDETrkELEEELGYRDELLITTEHYHLWAIedEQIRQKIGFydEGLIIEPDIEQYRELKLRLLNGAHTLGGGLAHLCGFKTVVEAMSDPFFSAFITHLMESEIATAIPYdpAVALAFSRQVADRFRNPHILHKWFNINQNYSAKILSRVIPTYLNYEARNglPEYMTFGLAVFIHYMKVVKKEGdpYLIQDPKAPFFYQKWQMASLPDMVQAILKDASIWGRDLNKVESVHSSIVKYLQSIAQNGVAETLKTLLE-
115 UniRef50_UPI00019136C4 D-mannonate oxidoreductase ... 400 1e-110 1 58.9% 152:487 1:338 -------------------------------------------------------------------------------------------------------------------------------------------------------LAHPQQPKSAIGYIVEALNMRREQGLKAFTVLSCDNVRENGHVAKAAVLGLAKARDAALAAWIADNVTFPCTMVDRIVPAATEETLQLVADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDTVGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYDTIADTMTNPAYRRAALALMLDEQAPTLSMpgTDLEGYANLLIARFTNPSLKHRTWQIAMDGSQKLPQRLLDPVRLHLQQGDDYRRLTLGVAGWMRYVGGVDEQGKTIDVVDPLLAQYQAIHQqqTPEERVRGLLAIESIFGNDLPKNHEFVQAVTDAYQQLLQNGAKATVEALAK-
116 UniRef50_A4XMX2 Mannitol dehydrogenase, C-t... 398 1e-109 1 26.7% 12:487 19:539 -----------QIEMPQFDIEDfnPTWIHFGAGNIFRGYIAALEQDLLERGEVQTGIIAAELFDYEIIDRIYKPYDNLSLVVTADAKGnqKRIIASITEALKCdkDDWARLCEIFKSASLQMVTFTITEKGYNIVDLNGEYL---PQVKEDinGPEKPKSSMGKVTSLLYVRYKNGKHPVAVVSLDNCSKNGERLYNSIIQIAKEweEGFVEYLSnsVSFPWSMIDKIVPR-PSDSIRELLEKDGLeiAPFVNTEKSQYLVIEDSFPNGRPPLEKAGVYFTntVENSERMKVQtlNPLHTALAIFGCLLGYKTIYEEVKDGCLKKLIEKIGYEEGLPVVVDPkiDPKEYLKEVieRFPNPYIPDAPQRIATDTSQKMPIRFGETIKAYSESpkSLRFIPLVIAGWLRYLMCVDDSGKPFEPsdPLLEELKKHmkAENLEEKLKPILSNEMLFRVNLFEI-GLASKVIYYFEEMTegAVRRTLEKYLE-
117 UniRef50_D2QJY5 Mannitol dehydrogenase doma... 392 1e-107 1 22.2% 1:486 1:512 MTADRIAARpaKLTRSTHPVPVYPEKILQFGTGVLLRGLPDYLIQKANSEGKFEGSIVVVKSTDSQT--NEFSDQDNLYTVAVRGVQQGQEVvvSAISRVLAAQT-QWNDVLVLARNPKLQIIISNTTEIGLNY--------------VEESIFQHPPQSFPAKLTAFLYERFRskAKGLVVIPTELVTDNGLKLREAVEKLAqeLGKLFTKWLKFHVRFCNSLVDRIVTRPTEEDKLALENEAGYEDDLLTFTEPYHLWAIEGDD-RVKQTLSFAgiIIDEDINFYKERKLRVLNGTHTLTMPLGYLLGLETVADEMRHPAMSKFVEQLMLNEIVPTVPdpGMDKAafAHDVLDRFRNPHLDHLLLNISLQQTAKMQARNVATLQRYYEqnTAPKLMAFGFAAYLLFMKATREENGqyPVRDDKAGYFYGDWKtaTVDAFVKSVLSDTTLWQADLTALPGFSEAVAENLNALLTEGVEKSLEKVI--
118 UniRef50_C3QT19 Mannitol dehydrogenase n=4 ... 392 1e-107 1 31.7% 17:483 5:440 ----------------NYNRAEIKAGIVHFGVGNFHRAHLEAYTNLLLEDPSQrwGVFGAMIMPTDGVlnALKKDDGIYQLTTCSPSGEqsMLIGSLVELAWGEIDS-EPIIAKIASEEIKIISLTITEGGYKVDFNQS-------------------RSVFWYVAEGLKRRMEKDL-PITILSCDNMQMNGNVAKCAFMSYFEEKYPEVAAWAKKKVTFPNSMVDRITPVTKPGK------------GTDVCCEDFIQWVIEDNFIAGRPAWEKVGVTFTHDVTPYEIMKLSLLNASHTLLSYPAYMEGFRKVDAVMADERYRAMIKLFMNRDVTPYVPVpgVDLEAYKDQLIERFSNKAISDQVSRLCGDGIAKFAVYVVPILKQMLQDGKDISIEAFLIAVYCKYLIGAreSGENIAISEpiTPADRKLISGGSPAE----FLKISPFVSLGLDKYPVFMEKYEQFYAMQVAEGLKVLLQ-----
119 UniRef50_UPI0001C347DF Mannitol dehydrogenase doma... 391 1e-107 1 32.4% 24:409 5:389 -----------------------KSVWMHIGAGSFHRAHQAWYLHRLCQQGDDSWSIALGNIrdANALLDNLTKQNGEYTLETVSPEGEryEKITSVRKVLHWD-ENLSQLVEQGCDKATRVIAFTVTEAGYYLTP-QHELDAEQPDIKADLTG--KMSTIYGALTQILRARLAAHGEPVTLLNCDNLRHNGERFRHGFLSFLQLKGeeLYQWVKENTRSPNTMVDRITPRPTPDVAERVKQHTGWDDKAPVMGEAFIQWVIEDDFINGRPALENVDVEMVESVLPWEEAKIRILNASHSCIAWAGTLIGLSFIDESTRQSAIKQMAWNYVTQDVIPSLSPSPLDLEQYRDVVLARFSNPYIQDTNQRVAADGLSKIPGFITPTLQECYQRQQTPAATAVLPALFSYFY-------------------------------------------------------------------------------
120 UniRef50_A8LED4 Mannitol dehydrogenase doma... 390 1e-107 1 30.4% 7:473 29:485 ------AAVARPLSRPGGdrPAARVRILHLGLGSFFRAHQAWYTDRAPDAR--QWGIAAFSHRR-RGLAHALTAQDGLYTLLTRGAEGDRFDVISSLAAAHAGS--DHDAWLAYWRQPALAVVTLTVTEAGYACDP-DGGLDLARGDVAADIAALRTDptAPARLLAGLHARARAGRSPVATVPCDNLAGNGAVAGRAVRELAAATGRPELVAAADGASWVTTMVDRITPGTTDADGAAVRAATGRDDAVPVVTEPFSEWVLSGDFPGGRPEWEHAGARFVADLTPFENRKLWLLNGAHSLLAYAGPRRGHVTVAQAVADPRCRGWLIE-WWAEASRHLSMTRTELESYQHALLERFENPRIRHLLAQIAMDGSLKLPVRILPVLRAERARGVMPRAGIRVIAAWMLHLREGTAS-----VRDAEAGRSVAAARAPLPEAASLVL----DLLGPGLGRDGELVAALAAQVTEL---------------
121 UniRef50_Q9XBD5 Putative mannitol dehydroge... 390 1e-107 1 31.6% 11:485 3:439 ----------PRLSRSTYPAASPRAGivHLGLGAFHRAHQAVFTQEAMLAEPGDWAICAVGQR-NPAVRDAMSTQDCLFTVTERDAEHEDLRVVDSVRDVLLAS-EQPDQVTAALADPATRIVTITVTEAGYRHDPATGRLRADDPEVAADVAG-RPPRTVIGQLIRGLKAREHSG---LTVVPCDNLPDNGRLVAGLLRDFCVLSgpELAERIAEQVRCPSTVVDQIVPATTDADIANVASLLGLLDRAAVVGETYRQWVIEDDFAAGRPAWDKAGVRLVADITPHQAAKLRLVNGTHSALTYLGLLAGCTSTAEVATRPEFARYAERLIREETGASLARFGIPVD--IDGLLKRLANPRITHRLAQIAADGVRKLPQRLLDPAAELLESGAEPRMICLALAGFLRHER-----------------------------ETPDCLFAARP----ALRDSRVFGELLTDAMHQLDRNGVLTTLRGI---
122 UniRef50_B1LA83 Mannitol dehydrogenase doma... 388 1e-106 1 26.9% 1:487 3:531 LNRETIKDRAagVRPPYFDLDEvqPKWVHFGGGNIFRGFVAAVLQNLLEEGKEDTGINVIELFDYEVIDKVYKPYDNLSIAVTIKPDGdeKRIIASVMEAldPLHPDWERAKEIFRNPSLQLASLTITEKGYNIEDQAGNL---FPQVMEDmnGPVSPQTSMGKVAALLYERFKAGRLPIALLSLDNFSRNGEKLYSSVKRISEEweKDFIDYLEKDVAFPWSMIDKIVPG-PSEFIKEHLEKLGIeiAPFVNMEWAQYLVIEDSFPNGRPKLEGanVFLTdtVEKAERMKVTtlNPLHTALAIFGCLLGYKKIADEMKDPLLKKLVEGVGEEGIKVVVDPGIINPREFLNEVInrLPNPYLPDTPQRIATDTSQKMPIRFGETIKAYHErpRNLKYIPLVIAGWCRYLMGIDDEGKEMQLsdPLLENLRSYVSkeSTDDHLKPILSSQQLFRVNLYEV-GLGEKIEELFKKMIT-GPR-AVRKTLE-
123 UniRef50_C0VU95 Possible fructuronate reduc... 388 1e-106 1 32.0% 28:474 5:393 ---------------------------VHLGLGAFHRAHQVWYTHEA----DPDWNYVSFTGRSA-RMSDLLTAQDNKYTLVTRSKDGDTFDLIETITETQPAA--NVERLMELMASSDVKVVTLTITEAGY---------------------DDTSDNSAPQRIAKGLTARKASGAGPIAIMSCDNVSGNGEKCKQAVYAVA---DDELKAWMDENVTFPTTSIDRITPATTDELIELVEKETGFADKAPVVTEPFASWVIEGEFPAGRPNWEKAGVEFVEDIEPFEHRKLWLLNGSHSLMAYYGQLKGHETVADAICDPAVHEKVEALW-DEAAQGLP---MDVTDYRASLIERFENPNIRHNLAQIAIDGATKQQNRAVPIYGIAHGDGA-----AFSIAAWIVYCLTTED------IKDTRADEINEAKGQSDPVQALCQVLGIDA------------DEKIRAHVEKIQ--------------
124 UniRef50_B6R3S8 Altronate oxidoreductase n=... 388 1e-106 1 22.6% 20:487 12:482 -------------------RPRPTPRVIQFGEGNFLRAFMDWKIDRMNERAGTDFGVVVVRPIDGG-IPFSLNETDGAYTAVTRGVDQddVRQVACIRKEMSAVSE-WHEVLALARNSDFTTVISNTTEAGITYLPDCKLQD-------------EPPVSFPAKVTRLLLERFNssAPGFQFLPCELIEKNGGTLEEIVLQHARDwpTEFINWISTHSAFYNTLVDRIVPGYPRGEAKTFEAELGYEDPLMVTAELFHFLVIEKREDQPELLLPLggTLITSNADGYKERKVAILNGAHTGFCPLALLSQTETVQSAIEHPVGRAFLEGMLQEEIIPFLSLPKDELSAFSDEVLRRFSNPYIKHRWHDISLNGIAKFQTRNLPRFESYIAAkkPPRYMALSLAAWLIFYTGAFKHAEELPARD--ADelNTLQVTEGTDTMIRAFLSEEAFWGKSIASDA-LVALILEALAFLQAE--PFTLDRLAD-
125 UniRef50_P58708 D-arabinitol 4-dehydrogenas... 386 1e-106 1 31.9% 22:475 7:459 ---------------------ARAPVLLHIGAGSFHRAHQAWYLHRVNAapGERWTLTVGNIRDdhATLAALAAQQGAYTLETVTPQGEryETIRSIARVLPWSAD-LAALINTGADPACRIVSFTVTEGGYYLDEHD-RLDVTHPDLAADLRGAR--STLYGALAALLAERRQRGAGPLTLQSCDNLRSNGARFRAGMRAFLALrdAALLAWFDANVSCPSAMVDRITPRPTDDVRTRVHAATGVDDRCPVMGESFIQWVIEDNFIAGRPAWEIAGAEIVADVHPYEEAKIRILNATHSCIAWAGTLAGLTYIHEGMRDAAIYRFAYDYVTDDVIPCLTPSPLDLERYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLAECFARGADPVATAVLPALFLGFLEGWARGTLPYVYQDGVMDG-AAARSIVEAPDSVAAFCSDRQLWGS-LAGRDALVQAVRAGRARVEA-------------
126 UniRef50_C9L6K8 Mannitol-1-phosphate/altron... 385 1e-105 1 28.1% 10:486 16:516 ---------AANIALPTYDIEKIrpVWVHFGAGNIFRIFMGGLADTLLSAGEMQTGIACVETFDFDVIDKIYKPFDNLVLAVTLKSDGsdKKVLGSLTEAYKASPDFPerLEEIFINPSLQMVSFTITEKGYALKDS---------------------SSAISLVCALLYKRYKANQAPLALVSMDNCSHNGEKLQKAVLDTAKEWqeGFLSYleKRISFPWTMIDKITPR-PADSVCKTLERSGVeiAPFVNAEAPQYLVIEDNFPNGRPPLEKAGVYLtdTVNKVERMKVTtlNPLHTALAVYGCLLGYTSIADEMKDCELSKFVHEIGLTEGMPVVTDPGisPSAFADEVInrFPNPFMPDTPQRIATDTSQKVGIRYGETIKAYIKKYGTASKLtlAIAGWCRYLIGVDDKGNPFELsdPMLPMLTQSLRGIEIEnqLKTILSDASIFGVDLYK-AGIGEKIEEMfeEIAsgGVRNTLKKYL--
127 UniRef50_B2VCG7 D-arabinitol 4-dehydrogenas... 384 1e-105 1 28.9% 24:476 8:459 -----------------------KSNWLHLGAGAFHRAHQSWYLNQLHQQGDNSWALSLANIRNsqKTLQQLAKQQGRYTLEIISPEGEIVYqiEAVENVILWD-EGLKSLVAVGASAATKIISFTVTEGGYFLDD-DGELDLEHPAIQADLAEQQETSTLYGALVKILRERMRNETGPVTLLNCDNLRDNGDSVARGLSQFVNAkdQQLLAWIEQNTSAPNGMVDRITPKFDAALFERLAEQGIENDGAPLSCEAFSQWVLEDKFIAGRPALENAGVEFVSSVTPYEEAKIRVLNASHSGIAWAGALLGKKYIDQSLQ-PLIKRWMSDYVLKDVAAALQPCDIDLAHYGETTLNRFSNKWVRDTTQRVSSDSIAKLQQFIVPTLKARYKQDATPAATLILPALWFRFMQQHHAGTLPFDYEDRALDEV-PFADIFNADDPLLAFTQQKKLFGS-LAGRPELYRDLSAAVDNVDKG------------
128 UniRef50_B8HCK0 Mannitol dehydrogenase doma... 384 1e-105 1 34.5% 10:478 16:486 ---------AAAPAVPQLSraKAPVRIVHLGLGAFHRSHQAWYTQHAGDAA--QWGIAAFTGRRPDA-AEALSGQDGLYTVVERGDAGDTFEVVSSIVEAVDGA--DAGRLTALIAAAGTAVVTLTITEAAYGL-GADGQFDRKAQGVAADLQELSapATPVGRLVHALAARKAAGAGPLAVVCCDNLSNNGTVASTAVVGMAEAWNPELAAWIVENISFVSTSVDRITPRTTDADVESVKAACGYFDNSPVVAEPFRNWVLSGDFPAGRPRWEDAGAVFVDDIEPYENRKLWLLNGAHSLLAYAGQLRGHATVAEALADPVCLAAVERFWNEAEANLtaAHGADLqaYREQLLARFRNARIAHHLTQIALDGSTKLRMRAVPVLTAERDGGRSGAGAAAMIAAWVAFC--IDATGRGRTVQDPLSDGIEAACALAGA-DRVRALLALLSV---PLSQDDAVVELVDGLAGGFARQGA----------
129 UniRef50_A4FJI1 Fructuronate reductase n=1 ... 381 1e-104 1 35.1% 24:479 23:481 -----------------------RTGIVHLGLGNFHRAHGAVYTAQAMAAAGGDWGIRG-FAHSSDRVVAPMRAQDNVYSILQLTERGAEAGLVDVHRDTGVAAQDP-AAVVDAIADPAHRIVSLTVSEVGYTRDPATGRLALDAPEVAADLTAGSTPRTAVGMIARGLEQRAASGE-PFAVLSCDNLQSAGDVTRAVVEEFLQAAgdDVLSFVSSSVSFPNGMVDRIVPRTTDEHSRIVADLLGVQDLCPVPAEEFTMWVLEDDFAGGRPAWDLAGATFSNEIEAYEMVKLRLLNGSHSLIAYLGILSGAPTIDVAWGQDFVREAVLNGITDDYLPTFTPpgFDADAYVSELDARWRNPLIGHATTQVGTDGSLKLLQRIPNAALFHLRRGDMPHHLALCIAAWIACvaGFTPEPLAERIVEPARDRLAAAVDGAVTVADHVRRIMNGGFFPDALAEQDAFTVRVADLLTLVVRDGVR---------
130 UniRef50_A3JTC9 Mannitol dehydrogenase n=1 ... 381 1e-104 1 35.7% 25:450 2:404 ------------------------PQILHFGVGNFFRAHQAAYT----ALAGGDWRISGVSMRS-DAMRRAMAADNFAYTLVVEGGPQSEFQVIDVIDDILLAPTQP-DEILTKLADADVQIVTATVTEKGYHL-AANGELELGDPDIQHDMNG--TPKTLIGFLAIGLSQR----KTPMTILSCDNRMDNGRVLERAVKKFASAAGLN-INW--NLFMFPNSMVDRITPATTDELRNRVA-AMGYPATAPVPTEAFSEWVIEDNFATPRPDWAAAGARFVTDVAPHEMRKLRMLNGAHSMLAYQGVLAGHEFVHQAIADPTLLATTQGLMA-EAALTLPVELQDMSayGRDLIARFANPSLAHSLRQIAMDGSQKIPYRFLQSRTALREMNMPSPCLDAALQAWMDFCRAETKAGRQ--INDP----LGRAIADASTRDDFAHILGVDP--------------------------------------
131 UniRef50_C1QE60 Mannitol-1-phosphate/altron... 380 1e-104 1 25.2% 11:486 18:537 ----------NNIEIPKYDIKQikPTWIHFGAGNIFRGFVARIADTLLNDNVINTGIIAVDTHSAGrlEKVYKPFDNLTLLASIKSDGndKKVIGSITDILHAdiNYYEELKKIFISDSLQIVSFTITEKGYSIKDSNGNYNKIVAYDIE--NEPKKAKNIMSIACAMLLERYKNGAYPIAMLSIDNCSNNGDRLKDSIIEIANEwdNGFIEYLEDntAFPFSMIDKITPR-PSEIISKKLESIGLEdaGFVNAEVPEYLVIEDSFPNGRPDLTKAGVYITdtVKNSEKMKVTtlNPLHTALAIFGCLQNYDFIYNEMKDPLLKKLVERIGYDEGMKVVINPKinPMNFIKEVieRLVNPYIPDSPKRIAADTSQKIPIRYGETLKSYVKNGLDTSSLiiTIAAWLRYLMGIDDNGNTMEIsdPMLEELQKHIKnnSVGDNLKPILSNKIIFACDLYDEknLGNRIEEYFKEMI-IGV-NAVRECL--
132 UniRef50_C6Y3U9 Mannitol dehydrogenase doma... 380 1e-104 1 22.1% 1:485 3:497 LSKDTLNSipNQVVAPDEKIFNLPEKVLQFGTGVLLRGLPDFFIDKANKKGLFNGRVAVIKSTSKGGT-KEFDDQNGLYTICVRGIENGQPviSAAISRVLTADQD-WNTILDIAASPLLKVIVSNTTEVGIQL--------------VEESIDQSPPQSFPAKLLAVLYARYKALGAAAAADitELISDNGKKLEAIVLQLanKLDEAFLTWLNAHVHFCNSLVDRIVPGKPDAtlANLETELGYKDELVIMAEPYRLWAIEgqKVAELLGLEAagVIVRPDIEIFKELKVRLLNGSHTLTSGIAYLLGIDTVTKAMNNSLTRNYVNELMMQEIVGAIPYdpDEAIAFANTVIDRFANPSIQHLWINITFQYTMKMKIRILPVLLNYYKLNQkpAHIAFGFAAFLLFMKSARKDGDqyAITDDEAAYFYNIAQQNE-SEYVNLVLADSKLWGTDLSSLQGFNETVKENYNNILKHGVADALARL---
133 UniRef50_A6W9X4 Mannitol dehydrogenase doma... 380 1e-104 1 34.2% 1:480 9:481 LSLDVLATLPSA-SRPLLDPRQLRAGVVHVGFGAFHRAHQAVYTEAAAAASTDPVGTVVVVPGSAATASHLL-EQDGLFSVTELSGDPGVPRVVASTTGVVRGW--DPDAVASLLLDPGTSVVTLTVTEKGYRRD-LRGGLDVTDPALADDLAGGRP--TAVGLLARALDARFRANGAPLTVVSCDNLARNGEVTSRVVREYVERSggAVLQWLQTAVTFPSTVVDQIVPAATPGVLDSAAQALGVRDELAVAGEPFRSWVLQDDFAAARPAWELAGARFVDDVAPHQLMKLRLLNGSHSALAYLGLAAGCATVDEAVATGWGSTLVQRLGG-EVAPTLPVPQEQVREYCHALGQRFANPGVRHRLTQIGDDGAAKVAERWFTPLRELRAARKPVTVLIAAVAAWAHATRP-DGEAQLFGTTDPLSAALADCWAHERGGPPVVAGL-LRTAGADDLAEDHALVDAVAGHLPAL-ARGVVE--------
134 UniRef50_D1YCS2 Mannitol dehydrogenase C-te... 378 1e-103 1 25.3% 1:487 5:525 LDALHGPALaaGLALPLFDVGEMrpRWMHIGPGNLFRVHIARLAQDIMNSGAEQCGIAAIAPRNPQRLDRGLTDHDLLTLGVTSHADgtDFGVIASISEGlyRRDDDFRRITEIACAESLQLITLTITEKGYQLNGYDGSYQDAVVKDLGRDPESDRMSTAMGLVTALLVQRFHAGATPVAVVSCDNFSHNGDMLRTSVLTIVAEwdHRVVEWIAEKVEFPISVIDKITPA-PSQKVAEQLASMGFEdaGFVNTEPAEYLVIEDRFPNGRPELEKAGVYFtdTCHRFERMKVTtlNPLHTALAITGVLLRKPTIDEAMKDPGLVGLVHRLGWQEGLLVVSDPgiDPKEFLREveERFPNPFLGDTPSRIATDTSQKIPIRFGETVKSYLADdaSLRAIPFVFAAWCRYLMGIADDGEPVELsdPLREQLESVVsgDDDSKVISPILSRADIFGVDLTMTP-LSEVVERFFIRLTAG--PGAVRSVLD-
135 UniRef50_C0QWB1 Mannitol-1-phosphate/altron... 376 1e-103 1 24.3% 11:487 17:537 ----------SDIKIPKYDIKQikPTWVHFGAGNIFRGFIARIADTLLNDNIIDTGIIAIDtdDYEMINKVYKPFDNLTLLASIKSSGddKKVIGSITDVVHAdiNSYEELKKIFISNSLQVASFTITEKGYSIKDLNGDYNITVKEDIN--NGPLKSKNIMSISAAMLLERYKNGAYPIAMLSIDNCSNNGDKLKSSIIEIAREwdEGFIKYLekKTAFPLSMVDKITPR-PSEIISKKLEETGLEeaAFVNAEVPEYLVIEDLFPNGRAEFEKAGVYVTDRITVqeKMKVTtlNPLHTALAVFGCLLNYNFIYEEMKDPLLKKLVEKIGYDEGMKVVADPKinPRDFIKEVieRLVNPYIPDSPQRIATDTSQKIPIRYGETLKSYIKNGLYTSSLilTIAAWLRYLMGIDDNGKTMEIsdPMLEELQKHIkkDSIGNNLKPILSNKVIFAVDLYDKenLGEKIEGYFREMIS--SENAVKECLK-
136 UniRef50_C7R2P7 Mannitol dehydrogenase doma... 376 1e-102 1 33.0% 21:469 19:478 --------------------AQRDPRIVHIGLGAFHRAHQAWYTQHAND----NWGIIAFTGRSPHA-ATQLTQQDGIYTLVTRSAQGDTHEIIDTITAAHDG--NDLTTLTAHIAAATTAIITLTITEAGYHCIMGtpTLNLNDPHIDTDITTLRTltTVPARIVLGLAARRDADAWPLAIMSCDNLPHNGAVTRAAITTIAHHVDPTLAQWITDHVSFVDSSIDRITPRTTDTDKRTVAHDTGYLDHTPVITEPFSSWVISGDFPAGRPAWENAGAQFVTDINPYERRKLWLLNGAHSLMAYAGQLRGHTTVSDAMLDPEVTTWINEFW-DEAARHLTEPDLDIPAYRVALTQRFTNPRIAHPLAHIAHDGSLKLAARAVPVYQAEHAAGRSGTASLRLLAAWCDHL--VIQHRNVIPIHDPNADALTHIiaHANTPRELATTQALITVLDPDLAANTTALTAIHTM-------------------
137 UniRef50_Q5WIW3 Altronate oxidoreductase n=... 374 1e-102 1 23.1% 24:461 22:473 -----------------------KETIVQIGEGNFMRGFIDWMVDQLHQQRLYDGRVAAIQPTPHGKIVPVLQAQDGLYTVILRGKLDgeAEVVQSIARGINPYND-WEEVKKLARSPDVKWLFSNTTEAGLVYQQERYEKD-------------KAPLSFPGKVTAFLYERfgALEAGITLVPCELIEDNGAVLKDIVETIAEDWEleFGQWLRKANVFCNTLVDRIVTGFPHGEEETWANRLGYEDRLLTVAEPYHLFVIeeRPLDERLPFEQAGLNvwEPVALHRELKVRLLNGLHTMMFALSFLAGEDTVKGALHSPRLRRFIERGLEQELIPVVNAPEEEKQAYAASVIERFENPFLAHKLTDIGLNAIYKFKTRLLPALEAHEQQDNEPSQLLASLAALLVYMKPQERDGaqIRENETALALLEATWCQYDAgeTISTLLQADGLWGRDLSRYSE---------------------------
138 UniRef50_C7PPZ6 Mannitol dehydrogenase doma... 373 1e-102 1 23.2% 1:479 5:491 LNKAHVLKHPELGVSAGY--FDYPERILQFGTGVLLRGLVDYLVDKANKQGLYQGRIVVVKSTGGDTT--EFSKQDNLFTTNIKGVSQGELviNASISRVLQSNAD-WEFVLQAVRQPALQTIISNTTEVGIQYVEEKI---------------DGVPSSFPGKLLAVLWERFqaSHTGFVIVPTELVVNNGQLLKEIVLKLanRLPATFLQWIEEDNHFCSSLVDRIVPGKPKE-LAVLEEKAGYTDGLWIDTEPYLLWAIedDRVKDILGFHQTdmLIARDITPFREQKLRILNGSHTISVPLGYLSGLNIVLECMEDANMRAFFRTVILEEILPTIKDICPQAPAFAEDVLDRFANPNIAHKLLSITFQESMKMNARNVKTirYYEKFQALPASMCLGFAAMLLFLRPeqRGEEYYTITDDNIAIFAEYWsgDAIAEMVQAISADQRLWEADLSQIPGFADTVTAHLQGMLQEGVK---------
139 UniRef50_Q0FGE2 Mannitol-1-phosphate/altron... 372 1e-101 1 24.7% 4:476 1:470 ---MNNISLPK-IHSTNYNKNECEIGIVHVGFGAFHRAHQAVYMDDYMSknDLRWGIAAVNLRESEttVQEIKA-NGGYLIKSYSSDGHDSVRMVRSHIGFYDWTTDIENTQNLLAVETVHLVTITVTESGYYTN-AYGQLDINEPTII-DEINNSNLKTIYGYLRNAINKRIMAHGKPITIACCDNIRQNGLMLKQNLISYLKACGDQLvdWVQKNAYFPCSMVDRITPQTSILLQEELSSLIGHEIYSPIMAEDFSQWVLQDISLGTLPALDIVGVTITKDIDPYEETKIRVLNGGHTALTYMAALEKMITFDEAMRSHQLLEHFRCFQVNEVLPALLLdpFSKNDYLAKIEERFCNKAIGDTISRICADGMAKFPIFIRPTLEGCLQQGIVPHFSIKSIASWHQFCLHVAAGKIDFKYVEPSWAFLETIIGT-------DEFITCQQLWSDIPNKYPDFTINLRNEIFEMEKK------------
140 UniRef50_C5RJ64 Mannitol dehydrogenase doma... 372 1e-101 1 23.5% 14:476 14:487 -------------QRSIYDKvkSPIKVMQIGEGNFLTSFFDWMLYKAIEAGKYEGSVALTCPLDFDKKINILKEQDMLYTVTQRGFKddESDIISVFSKVFN-YNVDWNSFMEIAELESLEVIISNTTEAGLAYKEV--ELDKVSVDGL-----------YPGKLTAFLMHRFEnkTKKLLIFPCELLDDNGKVLEEMVKKHAEstSDEFKTWVNESCVFLNNLVDRIVPGFPRENTEAYFEKLGYIDEAASVCEPFFLWGIEGSEEYDklPLKSAgvKWADSLYDIHLLKVSILNGSHTLITPLGILKGFERVDELVEDPEEKAFLNEALQNEIIPSLK--NEDAEGYAKTILQRFRNPHLKHKLESISMNSVSKFVNRDLPTVKAYIEDNNspKNMVIGLAGLLRFYqgHNFKGKEYPVFDVilDFMCNMNKEYSiqNYVKAILSNTELWGEDLTKIEGLTVAVSEALESLERK------------
141 UniRef50_A6EKW0 Altronate oxidoreductase n=... 371 1e-101 1 21.7% 11:485 8:491 ----------EHLQSPDLSQFNLPEKVLQFGTGVLLRALPDYFINKANGQGLFNGRVVVVKSTSKGD-VQSFQNQDGLYTICVRGLEQgeNIISAAISRVVSAEHD-FAEILTIAGSKELTLIVSNTTEVGIQFVPED--------------VHQSPPSSFPAKLLAVLYARFHadEADIVIVATELIPENGRRLHDIVIELcnKLNNRFIRWIDRRVYFCNSLVDRIVPGKPATSveEVQGLLGYEDQLLIMAEPYRLWAIedDKIAALIGLsdAGLIVTPDIEIYRELKVRLLNGTHTLSCGIAMLSGIKTVGQGMSEDSLKLYIKEVMYKEIISSIPYPVdeASSFADAVSDRFANPYIEHLWSSITFQYTMKMKVRILPLirFYEIFNEVPKLMAFGFAVYLRFMRVntFDGNNYLINDDQAEWFCQKCELPD-QEYIHAVMIAESLWGADLSRCIGFEVAVADYYHDISKEGVLQCLNSI---
142 UniRef50_C9C0V4 Fructuronate reductase n=16... 368 1e-100 1 25.4% 11:487 17:539 ----------KEVEIPHFDRASLrpVWIHFGGGNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEFvrILAATADSLYCHPdhFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYI--GPIAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAKEWQKefIQYleEIVAFPWTMIDRITPNPSLSVSKMLAKekGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTdtVDKADTMKVTtlNPLHTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPgiDPKIFLEEVItrFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIekDPQTLVftLAAWLRYLIGIDDQGKPfpSPDPLLTDFQHKLSDIqiHEKMAPILSNKEIFGVDLYQ-AELGRKIEEMFIKMVanAVRKTLQDYLQ-
143 UniRef50_Q02XT0 Fructuronate reductase n=7 ... 368 1e-100 1 24.7% 11:487 18:538 ----------AKINIPKFDQGKvnPVWVHFGGGNLFRCFHAVVAQDLLNQGELNSGIIVAETYDDEVIEKIYHAYDNRFLSVTMKSDGtdKELIASVSESFyeNTEGWAHLTKVFENPSLQFTTFSITEKGYSLRDS---KDQLTPLALEDMQGRSKPKTNMGAITYLLYARFKAGKFPIAMVSTDNFSENGLKLQEAILTIAKAweQDFYDYlpKKVSFPWSMIDRITPN-PSEKVAELLTADGFEdaPFGNTEEVHYLVIEDAFPNGRPALEKAGVILTdtVNDADQMKVtcLNPLHTALAIFGSLLDYHSIWEEVANPDLLALIKNLGYGEALPVVKNPkiNPTEFIDQLlkRLPNKNIPDTPQRIAADTSQKIPVRYGVTIGHYIANPreLEFIPLVIAAWCRYLIGINDELESFSPsdPLLEELQAFVAekEIHEILKPILSNHQIFPHEMYQ-TGLAEKIETYFEEMIqkgvLATLQNALK-
144 UniRef50_C8WWW7 Mannitol dehydrogenase doma... 367 1e-100 1 24.3% 21:485 20:478 --------------------RAMPIRVVQIGEGIFLRGFVDWLVHRLNESGTFQGRIAVVNPRPSGAhvHQFQEQDGLYTVLVRGMQDGRpeLVTSVARAFDSTRE-WAQVLQLARDPLVEIAVSNTTELGVRYEPV--------PRPMSDA----PPGTYPAKLTQYLHERYLaeTSRLIVVPCELIDDNGQQLRSIVERHAADwgGDFMRWLRDRVEFCDTLVDRIVTPYAGDP------PLPYEDALAVTVEPYYLFAIRGSelKALWPFEEVgvHYADDIRDFRLQKLRALNGTHTALANLGLMAGLETVLEVMQHPTLSAYVRHLVHGEIVPavSRPEM-LRDFAHDVLERFQNPYLEHKLRSIATNAVSKARIRLVPTLLDAVERLGDARRLTAAVAacLAYRPGMERAAEP----DPAADRLRALWQD-DLGASAHAILSDAELWSADLTQVPGVLDGWIRFVEMALREGPVQAVASL---
145 UniRef50_D0YQL5 D-mannonate oxidoreductase ... 367 1e-100 1 27.1% 1:487 3:535 LNLKNLEEIAaqVSVPGFDVSTMqpRWIHIGPGNLFRCFPARIAADLLERGE-NWPITAVAPRDLEDMEFQLPHHDLLTMKVTLNPDGTqyRVIAGIAEAivGTTADMERLFRVVRDPGVELISYTVTEKGYGILDGSGELQAGVLAAMEDSDpeHCQASTMVLSAVLLLERFAAGGTPITMLSFDNFSHNGDKLRDSVLTIARAwpAGFLDWLEdkVAFPITVIDKITPRPSPEIATKLA-NLGFTdaGFVNTEPTEYLIIEDKFAGSRPAWEDLGVQVVArcDDFENMKVTtlNPLHTALAVSGCLMNFPTIDAEMRDPALVALVHELGWKEGLPVVVDPgvKPEDFLREVLerFPNRYLPDNPARIAMDTSQKIPIRFGVTIRKYLETGRdlHAMPLVFALWCRYLLGVRDDGSPFEpsDPRLTELSAHVAGIsvHEALAPILSDASIFGLDLYETP-LAEATEQYFQRLIAR--PGAVRETLD-
146 UniRef50_C6JE46 Mannitol dehydrogenase ross... 361 4e-98 1 27.1% 11:486 17:537 ----------AGITLPSYDVEAvnPVWVHFGIGNIFRVFIGGIADGLLEEGVLDRGITCVETFDYDVVDKIYDPYDNllSVILHGDGTREYKVVGAFAEAVKanAEQWKRLKEIFTSKSLQMVSFTITEKGYALQKADGTW---FPFVEADinGPDKAVGAMAVLVAMLYERYKAGEYPIALVSMDNCSQNGAKLRESVLTMTEEwdEGFVNYveKVVAFPWTMIDKITPR-PSEQIAADLENLGVeiAPFVNAEKPQYLVIEDSFPNGRPALEKggVYMAdtVNLSERMKVTvlNPVHSATGPLGVVLGYDLFAHMLnnEDMMKMARMIAYDEGLPVVADPGisPQAFVDELfdRFPNEYLGDTNLRLAVDVSQMVGIRFGETIKAYVQKFGDASRLtlGIAGWLRYMLGVDDEGNKFElpDPMNEELQEQFKdeTFKDQLKPILSNERLFFTDLYKD-GVGEKVEDMFREMIagAVRATIHKYV--
147 UniRef50_C7PV24 Mannitol dehydrogenase doma... 360 6e-98 1 22.2% 20:487 13:476 -------------------RAVLPEKVLQFGTGVLLRGLPDYFIDKANKAGIFNGRIVVVKSTDKGNT-DAYSEQDYLYTHCIQGIMQgeYVVNDAISRVLSATGE-WEQILECAADPEMEIIISNTTEVGITLT--------------ADNIDAAPPASFPGKLLAFLLRRYRhiNKGMVIIPTELIPDNGTKLQHILLELAQqlEAAFINWLSAANHICNSLVDRIVPGALPAAAQAAVEalRYSDQLMIMSEPYALWAIETSSERVRKVLSFagVVLAPDINIFRELKLRLLNGTHTLSCGLAVLAGFNTVKEAMEDTAMESCISALAQHEIVPAITdrEDAALRFAGSVLDRFRNPFIEHRWQSITMQYTSKMKMRVIPVirHYQRLDEVPALMALGFAAYLLFMR-------DGEVTDDYAAYFKEKWQKLEPAVLVQTVLKDTALWGVDLTQLPGFSHAVTIMMGALLTEGAPSLIRRVSE-
148 UniRef50_C5BXX0 Mannitol dehydrogenase doma... 359 1e-97 1 30.7% 3:475 10:450 --SARGVSARPGVRGPLVEPAAV--GVVHLGIGAFHRAHQAVYTERAAaaGEREWGILGVTGRRPD-VARVLDASGGVYGVLVRDGADVSVDVVGAVVEAASPDQDA-ERVVAAIAAETTAVVSLTITEHGY----------------------AGPPFSPpeLLVRGL-RRRAAHGAPLSVLSCDNLVDNGAVLRRIVRA-AVSGDDGVARWVDDAVRFPRSMVDRIVPATTAEDRRAAAVLTGFDDAGLVVAEPFSEWVIEDDLAERRPRWELAGARVVPDVEPYERLKLRTLNATHSLLAYEGEARGHTTIAEALDDDELARRVEALMAESGLTLEQPPGIDVVAYRAEVLRRFRNRGMRHTVAQIGHDGSRKLPIRVGGTIGDLVAQGVTPDATARVLAAWAVHLR-------RGAVVDPLADELQAAARAARDaeLAELVLRLPGIVPDAVAGRRDVRDAVAAHTAEILA-------------
149 UniRef50_Q03U13 Fructuronate reductase n=7 ... 352 1e-95 1 25.8% 11:487 18:534 ----------AGIKVPTYDQAALkpRWVHFGGGNLFRAFHAAIANTLIEKGELDSGVIVGETYDDDVVKDIYQAYNNRILRVVTKADGndKELFASVAEAYfsHEDDWNNLFDVFKKDSLQVVTFSITEKGYNLRTVNGDldLTKADIA---NGPEKPRGNMAGLVSLLLARFNNGKAPLALLSTDNFSQNGDRLKESVLTIAKGwgADFLAYLQdqISFPLSMIDRITPNPAEAVGDKLAAA-GFEdaPFTNTEEAHYLVVEDAFPNGRPKFEDAGVIVtdTVNDADEMKVTtlNPLHTALAIFGSVLGFDSIAKELQNKDLVALIKQIGYVEGLPVVTDPkiNPKDFINQLvkRLPNPYIPDTPQRIATDTSQKIPVRYGVTIKHYDERDgtLEFIPLTIAAWFRYLMAVNDEGASFEPsdPMMADLQKYvdDVDVHAHLKDVLTNTSIFGQDLYAV-GLGEKVENYFKQMIAG--KGAIVATLE-
150 UniRef50_A4FJT9 Mannitol dehydrogenase n=1 ... 348 3e-94 1 27.4% 51:474 2:389 --------------------------------------------------ADPDWGIAA-YTFRNTELPRTLAEQDGLYSLQVRGEGEPRAEIVDAISRAHPGSE--TDQWLADLASPDVTLLTLTITEAGYRLSGDQDG-------------------TAIGRVLAGLRGRHRASGAPIALVPCDNLPGNGGVLREAIRTAAAGEAPDFRSWIEDHVSFVDTVVDRITPATTEQDVTATARLTGFEDRAPVVTEPFSEWLLAGDFPLGRPAWENSGARFVDDLAAYEQRKLWFLNGAHTLLAYAGPALGCATVDEAVRHPVLARLT-ASWWDVASRHASLPEEDLADYRQRLRQRFSSRGVRHNLLQIAADGSQKIPARILPVLRAERAAQRMPDAPVAALAGWLIHLR-------DRPVSDPRADELVSLAHSADAPRRVLSALDVT------LANDRELVSAVEDYVEHLR--------------
151 UniRef50_C7MAX7 Mannitol-1-phosphate/altron... 348 4e-94 1 31.2% 26:473 11:420 -------------------------RLVHLGIGNFARAHTLHATDVA-----GGWSVVAFTGRSA-TMADALNAQGGRYGLIVRGAEGDEVSLVDVIDEVHPAS--DVDTLVRLLADPFTAVVTLTITEKGY-------------------AAGSDPATSAPARIALGLKARREAgtEPIALVSCDNLTGNGEVLGQAVL---AELDEETKAWFPDHVDVISSMVDRITPSADENASETVRAQTGLADSVPVVTEPFTEWVIEDRFRGRRPEWEKAGVQFTDDLEVHELRKLRLLNGAHTLMAYAGQVAGVQRVDEAIAHREVRALVEQLWA-EARATLPLPAAELDAYTAALEERFRNPRLADNLIRIAADGSVKLPVRALPVIA---ERGGPEQAPGEVAAVAAWTAWVTDRVRAGEEVQDPKSEAIAAAASLEDTTERVSSLLAL-----LDVPAIDPLVDAVLAEEQRL---------------
152 UniRef50_D1BXA2 Mannitol dehydrogenase doma... 328 4e-88 1 23.0% 12:459 12:482 -----------ELTATTAPAPERPTTILQFGGGNFLRAFVDLMVHDANRAGVMNAGIAVVFTTPNAntFELLRRQDGRYHVLLEGVRDGEPvlVESVTTAVHAHRE-FDAYRALYLSPELTTIVSNTTEAGIVW-------------VEGDDLTAQPPASFPAKVTALLHDRWeaPDKGLRIVCCELIEDNATTLREYVLRHAAAAGLpfVAWVETACSFHDTLVDRIVPGFPRDEIDAVQAELGYRDDLVVKGEHFGVWAIATGEPGGplPLDRAgvEFLADIRPFRAKKVRILNGLHTAMAAVGLLAGRNEVSDAVANLTIASYLGHLLHGEVLPSIPEYSAslAEFADRITERFTNPSLHHRLADISLNSISKWQARNLPVALDAWGAGREAPLTVLAFAALAVLYSGrrVAESGFEVRDDAaaLVRDTFPAEGTDDDVERWLraAGFFSADDAAD-----------------------------
153 UniRef50_C5C1F0 Mannitol dehydrogenase doma... 325 2e-87 1 34.5% 27:446 1:402 --------------------------MVHLGLGAFHRAHQAWYTHRANLAASGawGIAAFTGRRPDA-ARALAAQGCAYTLLVREPDGDAAERITSISGAYDGA--DTAAWRGAVANPRVAVVTLTITEPAYG------------------------ATSAMRRLADGLAARRDAGAGPLAVVSCDNLPANGARTRDAVLGAAD--DPRLAQWITDHVSFVDTVVDRITPAATDDDRAASG------DPCVVVTEPFTEWYLAGEFPAGRPAWEVEGARFVPDVEVYTRRKLWLLNAGHSLLAYLGLARGHTSIDEAMADGECRRALDALW-DDAAPVLPLPEREIRDARAALVRRFTNPRIRHLLEQIAKDGSAKLPARSTPVVAARLADGATpdGQLRLWSAWLAHLrgWTSDADPGGA--PLAARARTSLAD-GAAAVVDHLL------------------------------------------
154 UniRef50_A6DPG6 Tagaturonate reductase n=1 ... 325 2e-87 1 21.3% 23:482 1:453 ----------------------MKNKILQFGSGVFLRGFWGWMVNELNKNENFDASITMVKLTPRGDL-SQFKETSGLYSLSTKGLLNGEveEIDIYQRFIHPYPEWVEFLL-TAEEEDLQIVVSNSTEAGIVYK--------------QCLFPNECPETYPAKLCAWLYKRfqSSDKAPLILPMELIESNGDKLQEIIIKHANDWGLdfITWVQKDCDFRNTLVDRIVTKGDKNDA---------------CVEPYHLFAIEGEEAEEILPLKKAGVnwTKNLPAFRETKVRMLNGGHTSMIYAAILSGETIVADALEKLEIDQFLRSILLDEVLPTLEAKGGdlTDYAEAVIERFKNPFLNHEMINIALNSASKLLVRILPSFNDSTKLNKkpEKLSKAIAAFFWFYRGseSEGLTYEFADdkAMSAIAKCDTSSAANFAKAILACSA-WKGAFNKHPDFEATLTKILEEFEEKGLKASL------
155 UniRef50_C8SYL4 Fructuronate reductase n=1 ... 321 3e-86 1 78.8% 1:260 1:261 MTTIATATLPKNVQYPQYDRSQLRSRIVHFGFGAFHRAHQALLTDRVLNNVGGDWGICEISLFSGDTLMSQLREQDHLFTVLEKGADGNQPIVIGAVHECLNARLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGKLDPTHPRIIHDLENPTLPQSVPGILVEALARRRERGLPPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPALADWIADNVSFPGTMVDRIVPAATPESLAEIATVLGSTIPAPSVANpfSGW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
156 UniRef50_UPI0001C347E9 mannitol-1-phosphate 5-dehy... 303 1e-80 1 20.5% 26:474 2:382 -------------------------KVIHFGAGNIGRGFIGKLLADANSQ--------VTFTDVNQPLIDQLAHQQS-YNVHVVGQEN-RIEKVQHIHA-----------------------VNSN--------DPKTIEF-IATADMLTTAVGPQVLEKIASTIAKGIIHRKSLGNnpLNIIACENMVRGTSQLKQHVL---AQLPEELHQWVEQHIGFVDSAVDRIVPPMDAAN----------DDPLDVTVESFSEWIVDQTQFVGDIPI-INGMELTDNLMAFVERKLFTLNTGHAMTAYLGQLYGYQTISESIGDLRIHTVVKSAMQESGQVLIQRYGFdhNQYIDKILSRFANPYLKDDVSRVGRQPMRKLsdRLIKPLLGTFEYQLPNENLIIGIAAALHFRC----------EADPQANEMAKLIADKGIYQAVVELCGLE--------QYPEVVDRICSQYQLLI--------------
157 UniRef50_A7FP92 Mannitol-1-phosphate 5-dehy... 302 1e-80 1 19.5% 26:476 2:384 -------------------------KALHFGAGNIGRGF----IGKLLADAGAQLTFADV----NQPLLDALNKRKS-YQVNVVG-EQARVEEVKNVSAVNSGSPE----VVALIA----------------------------EADIVTTAVGPQILARIAATVAQGLITRHQQGNtpLNIIACENMVRGTSQLKQHVF---AALSEDEQIWVEQHVGFVDSAVDRIVPPS----------EAGSTDILAVTVETFSEWIVDGTQFKGQPP-EIVGMELTDNLMAFVERKLFTLNTGHAITAYLGQLAGHQTIRDAILDPAVRQTVKGAMEESGAVLIKRYAFDPqaYINKILSRFENPYLHDDVERVGRQPLRKlgDRLIKPLLGTLEYQLPHDSLVTGIAAAMSY----------RSEQDPQAQELVTLLAQLGPKAALAQI--------SGLPADSEVVEQAVSVYNAMQQK------------
158 UniRef50_A9WVA8 D-mannonate oxidoreductase ... 302 2e-80 1 30.2% 10:407 5:364 ---------PTALSRSVLNLPAPAVRIVHLGLGAFHRAHQVWYTQHA--ADGAEWGITAFSMRSAAAADLL-AAQDGLFTLVERGAADS-FELLWPILEVGDASADAGarMIELIAAPSTAVVTLTITEAGYVAGSVAVTLLRAGLAARAAAG-----------------------AGPIAVVPCDNLSGNGDLLASLIFPAGRA----------DGVSFISTSVDRITPRSTSADQERVLPATGREDAAPVVTEPYRSWILQGDFPAGRPRWEPAGAMFVADVTPWEQRKLWMLNGAHSYLANAGLVRGLETVAQAISDPELRAGVQALWA-EVAAHLPA-EVEAENYAAQLIERFENGRIEHRLSQIAADSVAKLRVRVPPVLRVEQMAGRSGAASRAVLEAWVR---------------------------------------------------------------------------------
159 UniRef50_B0K280 Mannitol-1-phosphate 5-dehy... 295 3e-78 1 21.1% 26:475 3:383 -------------------------KAVHFGAGNIGRGFIGY----LLYKSGYEITFVDIS----KELVESINNYK-RYNVIIL-KDNVEKEEVKNIKAIHIEDEENLSKAI-------------------------------VDADIVTTSVGANNLKSIGEKLINYLKIRKANIDKPLNIMACENALFATNILKNSILE---KGDRDFIEYVNQKIGFPNTAVDRIVPNVD----------IKKELPIDVAVEDFYEWDIEKKAIIG--DLNIRGAELVDDLEPYIERKLFLLNGAHATTAYLGYLKGYKYIHEAIEDDFIRNIVSR-MQEEASLALSRKhdDLERYASKVIKRFKNPYLKDEVVRVGREPTRKLSvrLMMPAKLCYEIGITPEFILYGIAAGFLFDYKE----------DPQACKIQDDIKNFGLEKTISKVTGLE--------ENSDLLQEIVKKYKELKE-------------
160 UniRef50_A7MWS7 Mannitol-1-phosphate 5-dehy... 294 4e-78 1 19.0% 27:473 4:382 --------------------------AVHFGAGNIGRGF----IGKLLADAEVEVTFADVDA----PLVDQLSHKQ-EYKVKVVGTE-CQIDTVTHVTAVNSASEDVIDRIVK--------------------------------TDLVTTAVGPNVLDIIAKTIATGIAKRFAAgdKPLNIIACENMVRGTTHLKGEVYKH---LDESLHSKADELVGFVDSAVDRIVPPAEAAN----------DDPLEVTVESFSEWIVDEQQFKGEIP-DIAGMEKTNNLMAFVERKLFTLNTGHCITAYLGCLKGHRTIREAIEDPSIHAEVKQAMQESGEVLIKRYGFdhNAYIEKILGRFANPYLVDEVDRVGRQPIRKLGarLVKPLLGTIEYGTENKTLLKGIAAALKYTNDT----------DPQAVEQQNSLKEVGVKKTLATYTG--------LAENSAEVTQIETLYNQL---------------
161 UniRef50_A4IPF0 Mannitol-1-phosphate 5-dehy... 294 5e-78 1 21.1% 26:476 2:384 -------------------------RAVHFGAGNIGRGF----IGSLLAASGYDVVFVDV----NEQIVRLLKER-GEYRVIIAGERQEE-QWVRGVS-ALNSQTE-RDDVIEAIASADL----------------------------VTTAVGPHILPVIAPVIAAGLERRFTVHQKPLHVIACENMIGGTETLKQHVVTHLSEAGRQL---VEECVGFLNCAVDRIVPNQTND------------DPLAVTVEPFFEWAIETKNTIGAVP-PIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYQKQYRTVQEAMKDSGIRESVEQALRESGAVLVKKHGWdhRSYIETTIGRFTNPSLSDDIVRVARSPIRKLgdRLVAPAVQYYtfERVPSGLVKGIAALLLF----DETG------DAEATALQQTIEQSGVEGALVQY--------AGLDNSHPLVVAVKEEYKKMQKE------------
162 UniRef50_D2R7C9 Mannitol dehydrogenase ross... 293 1e-77 1 20.6% 21:403 2:370 --------------------AELSETVLQLGAGRFLRAFCDRFIHQANASSRPVGKIVVVQST-AGSRADSLASRPEGYSVLVRGFQNGEPvlVASISRALVAGT-QWSEVQRLVQTDALKFVISNATEAGYKLADG-------------DAPSDAPPSSLPGKLAQLLHLRYAKDLAPLVMLPCELIESNGAKLRDLVVEQARRwgEAFIDYVTNKTQWVNSLVDCIVTSPEPTNPHLTT------DPNLVCAEPYQLWAQQPLDPSMPQPIDHPAIRWVSDLSPFYLRKVRILNGLHTAMVAKFFGTGPVTVADVLADLEKAKWLRALLFEEIVPTIAYRVSDVAEFADQTWDRFRNVHLNHQLKDIALNHAAKLQVRLAPTADEYQrfGCRPAKLDEALA-------------------------------------------------------------------------------------
163 UniRef50_C9KJT2 Mannitol-1-phosphate 5-dehy... 291 3e-77 1 19.6% 27:450 12:374 --------------------------AIHFGAGNIGRGF----IGELLVQSGYEVTFVDV----NDELVKTINEKK-AYNIKIVGDEPQTVHV------------------------EHVKAINSNT-------NLEDLLTAIVKADIITTAIGPNILKFIAPNIAKGLERRVKVNETPLNVIACENMVGGSTVLKNFVYEH---LSDEAKPLVDKLIGFPDAAVDRIVPLQHNEE------------PLLVQVEPYCEWDVNRTQAKGEVP-EIKGLTWVDNLQAYIERKLFTVNTGHASIAYMAYQKGIKDIYSAMQDPEIVAFVRKVWGETGSMLIEKYGFDpqKYVETTEKRFANPHLSDEVTRVARGPKRKLGarLVSPATQLIEQGKTPSALAKVIAAALHF----DYEG------DKEAVEVQAYVKEHGYEEALTHFTGIEK--------------------------------------
164 UniRef50_A1SR48 Mannitol-1-phosphate 5-dehy... 288 3e-76 1 19.4% 26:474 2:382 -------------------------KAIHFGAGNIGRGFIGKVLSDA--------GIKVTFADVNKTVVNALIAR-NEYDVNVVGAD-CVVEKVTNVTAVNSAGSE----IVKLIAESDL----------------------------VTTAVGPTVLNIIAKTIADAIELRLNSGNkpLNIIACENMVRGTSQLKAQVFKY---LPESLHVQSDQTIGFVDCAVDRIVPP----------AEAGETDPLAVTVETFSEWIVDQTQFKGEIP-TIKGMECTDNLMAFVERKLFTLNTGHLITAYLGVLAGYETIKESIEDEAIRSDVTAAMQESGEVLIRRYGFDPqaYIQKILGRFANPYLRDEVDRVGRQPIRKLSarLIKPLNGTLEYGLPNGHLIKGIAAAFLYKND----------QDPQAVELQAMFAEKGLAATLAHY--------SGLAVDSETVKLVEQAYQSLK--------------
165 UniRef50_C9RTC9 Mannitol dehydrogenase doma... 286 1e-75 1 21.1% 26:476 2:384 -------------------------RAVHFGAGNIGRGF----IGSLLAASGYDVVFVDV----NEQIVRLLKER-GEYRVIVAGEQQEE-QWVRGVS-ALNSQTE-REAVIEAIADADL----------------------------VTTAVGPPILPAIAPVVAAGLQRRFAIQQKPLHVIACENMIAGTEALKTHVFEHLSADEQRLA---NQSVGFLNCAVDRIVPNQTND------------DPLAVTVEPFFEWAIEARNVIGAVP-PIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYLRNYETVQEAMNDEDIRWNVEQALSESGAVLVKKHGWDANeyIDTTIGRFMNPSLSDDIIRVARSPIRKLgdRLVAPATQYYafERVPFGLVKGIAALLRFDDASDA----------EAAALQQTLKQRGVEEALWQY--------AGLDRGHPLIAAVKEEYGRMEKN------------
166 UniRef50_Q8EN87 Mannitol-1-phosphate 5-dehy... 284 4e-75 1 17.3% 25:476 2:385 ------------------------KTAVHFGAGNIGRGFIGL----LLYQSGYQTIFIDV----NNQVIDEINKQKS-YHVYLAGKEKQEL-TVNHITG------------INSIKEPD------AVTEA------------IVKADVVTTAVGPTILPVIAKAISKGLQERTKQNNSPLNIIACENMVGGSSLLKEHVFE---SLEAHKIGEFDRLYGFPDAAVDRIVPNQTNKNL------------LDVMVEPYYEWVVEKKKIVGEVP-PIFGITYVDDLAPYIERKLFTVNTGHAIPAYLGTHLGYDTIVEAMKDLRIDDTIYGALAESGEALIHAYGFnhQEYVSKIIQRFQNPYISDDVKRVARGPIRKLGarLVKPALMYIEygKIPVYLAKTIAAALLFNNDEDRE----------AIELQKKISATGYQQAFVEVSGCDS--------DSILTKKVIEQLRLLQNK------------
167 UniRef50_UPI0001C42D08 mannitol-1-phosphate 5-dehy... 278 3e-73 1 20.9% 27:472 3:378 --------------------------AVHFGAGNIGRGF----IGEVLHKNGYDIYFVDV----AQPLIDQLNEQKSYY--IRLAQEKEETVLIKNV-YGLNSQTQA-DEVIDTLAKADLITVS----------------------------AGVNILPLIAPILAKGLLKRVEAGAGAVDVIACENAIGASTTLKGHVLD--EMKDNKAKEAILANVGFPDAAVDRIVPNQTR-------------DGLNVLVEPFFEWVVAAK--GMKTGERLQGVNYVEELNPYIERKLYTVNTGHACLAYVGFAKGIPSIAEAVADQSIRKELEEVLKETSRLlyQFDGAELKEYREKIISRFENVHLSDPVERVGRNPLRKLSarLIGPLVQLYDRGIQSPHLVKVAAAAFQFDVPSDEE----------SVKIQSMLKEKGLEETITKVTS--------LSADHPLVTQIKEQLEA----------------
168 UniRef50_C2KB11 Mannitol-1-phosphate 5-dehy... 276 2e-72 1 18.8% 26:476 2:386 -------------------------RAVHFGAGNIGRGF----IGETLADNGFGIDFVDV----NETIIDELNKR-GEYDIELAAPGKKRIH-VSNVDGINNAK--DPDKVVEAIKSTDM----------------------------ITTAIGPKILAIIAPLIAKGLTARIQSGntPLDVIACENMIGGSEHLKEEVYKH---LDDDVKPELDKYIGFPNAAVDRIVPIQHND------------DPLFVSVEDFKEWVIDESQMKNK-DIKLKGVDYAPDLEPYIERKLFSVNTGHATVAYTGKSLGYDTIGDAIKDPFVLKQVKRVLSETRSLLYHktEESLEEYHNKILSRFQNPYISDDIARVGRTPIRKLgeRFIRPIRELKDRGLDYSALMETVGRIYHFD----------EPNDKESVKLMQMLKDEDLKDVIVETT--------DLKDDPELVDEIVKSYHDAEAD------------
169 UniRef50_C4L274 Mannitol-1-phosphate 5-dehy... 275 3e-72 1 21.3% 26:476 2:376 -------------------------KAVHFGAGNIGRGFIGL----LLNQSGYEVTFVDI----NDTVIEALEVKRH-YEVG-FAEDGVDRIVVDRVRGVNSLKE--PARVVDLIAEADL----------------------------VTTAVGPSLLSKVAPLISEGLRAR-EVEDAPVYVIACENMIGGSAILRQEVEACGGVG--------EANVFFPNAAVDRIVPLQQHE------------DPLYVEVETFHEWVIETQGLNEQPP--IQGVTWVEEIGPYIERKLFTVNTGHAIASYIGSLFGKATIDEALKDRRVRQVVQGALYETGWLLLEKYGFEAKeyIQKIIKRFENPKLKDEVSRVARSPIRKLgdRLVKPARELMDNGIEPNELAYGIAAALHYYNPE----------DSESSELNLSIEEHGISSTIEKYLH--------LHEGDTLTQLILDQYHLIREE------------
170 UniRef50_C4V0J5 Mannitol-1-phosphate 5-dehy... 272 2e-71 1 19.3% 27:450 6:368 --------------------------AIHFGGGNIGRGF----IGELLVRSGYEVTFVDV----ADALVDEINAR-RSYDIEVVGDTPKKIHV--EHVKAINSNKD-LEALLDAF-----------VT-----------------ADIVTTAIGPNILKFIAPNIAKGIARRLEKTDAPLNIIACENMVGGSTVLKNFVYEHLA---DDIKEKAAHCIGFPDAAVDRIVPIQHNE------------DPLLVKVEPFCEWDVDRTGVVGAEP-QIEGLTWVDNLEAYIERKLFSVNTGHASIAYMAYLKGIEDIASAMQDEEIVAFVRRVWAETSELLIEKYGFdhAEYIRTAESRFKNPHLSDAVTRVARGPKRKLGarLVSPANQLVARGKKPEALATVIAAALHFDYAE----------DPEAVEVQTYLKEHGFEKALTHFTEIPA--------------------------------------
171 UniRef50_Q2B9X7 Mannitol-1-phosphate 5-dehy... 269 2e-70 1 21.4% 25:450 5:366 ------------------------KKAVHFGAGNIGRGF----IGALFSKSGYHVTFVDI----AEEIINLLNEQ-GEYKVNL-AAENGSSEKISSVSGLNNMTQESQ--------------VIEAIGEAEY----------------LTTAIGPNILPRIAPLIAKGIAERVKKTDDKLYIIACENQISATDLLKGYILE---NLDEETAGKLEGRVFFFNSAVDRIVP---------IQNNQGSLD---VLVEPYYEWVVE--APTDIPAVE--GMKIVPDLAPFIERKLFTVNTGHAVIAYLGYLAGKETIDEALKDEAVYKQAEATLKETGAYLVKEYGLDAEeyIKKIIGRFQNGFLNDGVTRVGRSPIRKLgdRLVRPAEQAMKAGLPFENLAKAIAAALHF----DFQG------DEEAVKIQEMLKEHGPLYVLKEVSGLEE--------------------------------------
172 UniRef50_Q5WDV0 Mannitol-1-phosphate 5-dehy... 268 3e-70 1 20.1% 26:468 2:373 -------------------------KAVHFGAGNIGRGF----IGALLVDAGYEVTFVDV----NEKIIDALNER-NEYKVTVAG-ERKETETVTNV-RGINSKTNEKEAIDAIAE-----------------------------ADIVTTAVGPTVLPYIAKTIAQGLKQRTAS--KPVNMIACENAIRATSQLKKDVLSH---LSEEETTALLKDAGFADAAVDRIVPNVQSD------------DILHVTVEPFFEWVVEKPALKGD-AVQLGKAVLVEDLAPYIERKLFTVNTGHAVAAYVGYRKGKKTIKEALADDYIKHRVRGALNETKAMLVEEYQFDAEayIDKILLRFQNPHLEDLVERVGRGPIRKLgdRLVKPAKYLAEKGLHPESLAETIFDALHF----------YAEGDPESEELRALVDEKG---YVDAFCEISK-----LEKDHPLVEIVAK--------------------
173 UniRef50_Q1QWS2 Mannitol dehydrogenase-like... 267 7e-70 1 23.1% 20:405 4:371 -------------------PTLAEAGIVQFGTSRFLLGHVAAFVHASREAGHTRDGILVVQTSPREAGKQKARDLdrQYPLAIRGrdIDTRETVTSIAGCWIAD-EQWDALERHIVEHA-RFVVSNTGDSGYRVDD--------------DSALAAVPTSFPGKLAKLLHARYRAGREGLTVLPCELVSRNGEQLLALVRELAQraDADFDNWLTTRCLWANTLVDRIVSAA--------------LEPVGAVAEPYALWAIED-QPGLELPCRHPDVQRVTSLAPYEMRKLHILNLAHTYLVHRWQrsHIRFVREAMDDPAWAAELRQVLDDEVLPTlhLERPSLEAYRDATLERFANPYLDHALQDIAQHHATKCQRRLQPVVESARRRGIATPRLDDAISSA-----------------------------------------------------------------------------------
174 UniRef50_Q0CXS6 Mannitol-1-phosphate 5-dehy... 266 1e-69 1 16.1% 23:476 1:386 ----------------------MGKKAIQFGGGNIGRGFVAEFLHEA--------GYEVVFVDVMDAVVSALQTTPS-YNVTEVSKDGENTKTISNY-RAINSKTNESDAVKEIAT-----------------------------ADVVTCAVGPNILKFIAPLIAKGIDARTES--KPVAVIACENAIGATDTLHGFIKEH---TPKDRLDTLYDRARFANSAIDRIVPNQPPNS------------GLNVRIEKFYEWAVEQTPFGSFGHPDIPAIHWVDNLEPYIERKLFTVNTGHATTAYYGHLRGKKMIADALADDEIRSMVHKVLDETASLIVSkpEDEQKEYVDTIIGRMSNPYLEDNIERVGRAPLRKLSrrFIGPASQLAERGQKFDALVDAIEMALRFQN---------VPGDQESADLAQILKQKSSEDATSELTGLE--------KDHPLYSPVLERVAKVQQD------------
175 UniRef50_A6WFS7 Mannitol dehydrogenase ross... 265 2e-69 1 27.3% 6:411 11:379 -----LRSTPTETPEPAvdRGLRTPAVVHLGVGGLRLAHHAVCLHEVVRRrsDDWGLVHVELRPpdGLIRLDRERDHR--VQLPGTSSPEFREVEVLTE-FTTSADDSAAVLDVLADPATRLVTLRVSE---------------EQEFFGLCAAPEHprIAHGYLVRALARRRDAGLPPFTVLSCDPVPRNGARTRDAVLELARRTDPLLADWIGRDVRFPGSLVDPTLPGGS--------------------ALPFR-WVVEDDFGHGRPPLEEAGAHLVTHTAPHEQLRMHLLDGARCALGLVGGTAGARTTAEALADPRVRAFLGGFLEEAASSLLHVPGVDLPGYRAAVLARLAG-----ADEPLPRSGSAAVSAVVLPSLRQALDHYRPRRHLVLAVAVWLLTLPG-----------------------------------------------------------------------------
176 UniRef50_C0Z8I6 Mannitol-1-phosphate 5-dehy... 265 4e-69 1 19.2% 27:475 3:381 --------------------------AVHFGAGNIGRGF----IGQLLQKAGYEIAFVDV----NAALVDELNERK-MYRVQLATTGKPESVVEG--VRAINGQ------------------------------DVAAVAEAIATADLVTTAVGPNILPHIAGAIAAGITQRLTVHARPLNVIACENMIGGSEKLKEHVYEHleSVQAQAAQWI----GFPNAAVDRIVPLQQHA------------DKLLVMVEPFFEWVVDSSQIVGEVP-AIEGVTYVEDLAPYIERKLFTVNTGHAVIAYLGYQLGMKTIDEAMRDDRIVQATRGALQETGALLAAKYGFDPqqYVEKILGRYTNPLLSDDIVRVARSPIRKLSqrLVGPALQCMEKGMNASYLGLAIAAALAFDYPE----------DAESARIQASLKEFGWENTLHNCTGI--------PAGHPLEEIVREQARRLKE-------------
177 UniRef50_B8D8D5 Mannitol-1-phosphate 5-dehy... 262 3e-68 1 17.0% 26:449 2:364 -------------------------KALQFGAGNIGRGFIG--------KTLSESGFSVIFSDVNQNIVDAIN-YNREYFVKIIGSNQNKTVNIKRVS--------------------------------AINSNDSNIKKIISSVDLITTAVGPTALEKIALIITQGIIFKIKNqtKPLNIIACENKIKSSSFLKQVVLK---NLPIKYHDYLNKYIGFIDCSIDTIIPSINN------------KDDLFLTVEEFKEWIVNINQFKGAV-LKIVDMKFSNNLDAFIERKLFTLNTGHAIAAYLGLIKNYKTIQDAISDKKIRVIVRSAMEESGSVLIKRYNfdHLDYIEKIFLRFENPFLSDKLERIGRNPLQKLRrrLIKPFLGAFEYNLPYSNLAKGIAAAFYYHNK----------NDLESIELSSSIKKQGLESTIIKICDLP---------------------------------------
178 UniRef50_D1APL6 Mannitol-1-phosphate 5-dehy... 257 5e-67 1 18.4% 25:476 2:384 ------------------------KKAVHFGAGSIGRGF----IGDLLHDTGYEIVLVDV----DKNIVEQINKTNS-YDLYII-EENYKKKTIDNVKAVLLTDTDKIAGEIAGA-----ELVTVSV--------------------WVDNLPGVAVP------LLAGLKKRVGKEAGKLDVLTCENAIHNGSILKNEVLKLDADFTEDM---LDKAAAFPDTAVDRMVLASERNGVKSVDIGL------------AHELVIEKSKLTDPESEPVKGAVYTENMDKYIERKLFIINGGHAWAGYMGHICGFTTMQEVFEDENFTSSVREVMQEIGALIAQKYNfeLNNYIDFVINRFKTPGITDYISRVSRNPIRKlgERLTGPCIQCEERGLKNDRLIEGIAAALLYDISEDKQ----------SSELQTHIKEHGIEESVS--------FYTSIPADSKLHKKIVENYKILSEK------------
179 UniRef50_A2RH97 Mannitol-1-phosphate 5-dehy... 255 4e-66 1 17.2% 25:449 2:368 ------------------------KKAVHFGAGNIGRGF----IGEILSKNGFEIYFVDT----NKAIIDELNTR----HSYEIGIASSSPEKISVSGVFGINNGENPKDVIEAIA----------------------------QADIVTTAIGPNILPYIAELVAKGIQKRkeNKQVQIDIIACENMIGGSEFLEKKVAEYLSDSD---KVYLANYIGFPNAAVDRIVPGQKHE------------DLLYVEVEPFCEWVIDESQIKNK-SFKLEGVHYASNLEPFIERKLFSVNSGHATVAYSSAYKGYKTILEGLQHKEILSALKGVQKETRALLLAktEEDLMSYHQMIISRFANPKIIDEVTRVARTPIRKLgeRFIRPIRELNERG-------------LSYQNHLDIVGKIFAynDSQSVQLQEKLSTMDFQRLIEEVTGLS---------------------------------------
180 UniRef50_A6LQT9 Mannitol dehydrogenase, C-t... 254 5e-66 1 17.6% 26:450 2:366 -------------------------RALHFGAGNIGKGFIGY----LLNKAGFDVCFVDV----NQSAIDKIN-RNKRYLVELLD-DDHTVEVISPVS-ALNSITQK-EEVLNSI----------------------------VKADIITTSVGIGNIPRIAECIAKGLLKRIKINKTKINIIANENAINASSTLKKEVEKY---LSNEEINKICEYVGFPNSAIDRLALSKENE-----------EDEVAL-VEPIYEWVINESEMVNNNLPYIKGVTYVANLTPYIERKLYCVNMAHAATAYLGFLNGEKTIQDTLKSHVIESIVKGALNETAQYFIKEYDISLEefMEKILLRFKNKNISDDILRVGRSPVRKLgeRLVGPTLKLYEKEYPVKYMAMLVAGALLFDNPEDEE----------SVILQQYIKENGIEESIRHFTGIDD--------------------------------------
181 UniRef50_B0MBD0 Putative uncharacterized pr... 253 1e-65 1 17.1% 24:450 15:380 -----------------------KMKAVHFGAGKIGRGFIA----DLLHDTGYEIVFVDV----NEKVNEELNKYHNYYLYVI--EEDYRRKEIDKVS-ALSPITEE-DKVVEAI----------------------------VEADVVTTAVLADNFPKIAGTLAKGLKARLEAGKERVNVIPCENALFNGDLLLKELVKTEIASEDDFL----KAAAFPNTAVDRMVFGTDKDGRDGID------------IGKDHELAVEVNKLVDPEKLPIAGAEYTDNLQKFLERKLYTINCGHAWSGYIGKLMGYEIIQDYFAVPENIEMTREVMREVAALMVAKHGfeMEDYITFALNRFCTPGIKDTITRISRAPIRKlnDRLVGPAVQCEERGLKNTLLLRGIAATFLFDVKEDEQ----------SVEMMQYVADNGIEDAVTHFTGIEA--------------------------------------
182 UniRef50_D1AQI8 Mannitol-1-phosphate 5-dehy... 250 6e-65 1 15.7% 27:473 3:381 --------------------------VFHFGAGSIGRGF----IGKILSENSYNVTFIDV----NEEIISQLNK-DNEYTVETVGA-NSKTETVKNVCGLLSGDLEGIKR-------------------------------KVPETDLITTAVGANVLEIIAPTVAEIIKFRKNSGITriNIIACENKLEASTFLKSKVEKY---LDENEKEYMETYAGFVNSAVDRLIPPRKIEGKEATY----------TIVEDFNEWIADETLIKGELTLK--GMIKKKDLTPYIERKLFTVNTGHIIAAHMGVYMNYETIDQAVCDEKIRKIIIGAMEESGAVLIKRYGFDKEeyIQKILKRFENKYLGDSTVRVGREPLRKLGvrLIRPLLGTLEYGLPNENLLTGISYALKYD----------VPSDRESVELQEMLKTAGVEETLKKVTENSIP--------DELITIIKSNYEKL---------------
183 UniRef50_C8WQV8 Mannitol dehydrogenase doma... 247 1e-63 1 21.3% 26:476 3:381 -------------------------RALHFGAGNIGRGFIGW----LLAEAGFQVTFADVVP----GLVNELAA-KRSYRVIELGEEKRVVEV-----QGVDACLLGSERCIELAA----------------------------TSDWITTAVGVRHLEGVAAVLVEGFRRRMQAGREgvIVIACENAVRATSQLRHHVERLA---DDALREFLDACVRFLDAAVDRIAPN----------REGHAEDALDAVVESYYEWVVEASPVPGAPH----GISWVSDLDPYLERKLYLVNGAHAAIAYLAHLRGITTIGEALSRKDIEEHAARF-QEEAAHGlaFDVADLAAYAEKVRTRFANPYVVDHVARVARDPLRKlgERLVGPLVAAAEAGSETTAIERAIASALYYV----------DENDEASVELQRRIATDGVEQVARAVCGLE---GPRLRG-------VMAAYRELQAE------------
184 UniRef50_C9B6N7 Mannitol dehydrogenase n=1 ... 245 2e-63 1 17.0% 26:472 2:377 -------------------------KAVHFGAGNIGRG----LIGQILHQNGFDLCFIDTNP----ELIHQLN-QDKGYTI----------EIIDEMNR-----SDFIDHVVALNSLSELEEVITAT----------------KNADILTTSVGAINLVKIAPIIAQALSKRFEQKHS-INIVANENVINASDVLKKEIYSLLSEKEQE---NFDEYAYFVNTAIDR----------QSLGKVLG--GKMISVVEPYYEWIMDRQQLDPTTSFDLKNVNLVDDMEPYIERKLYIVNAAHAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHfeLTSFVEKTLNRHGNQKLSDEITRVGSSPIRKLgdRLIAPIVKLDSYHLPYDAGIKVIAAGYHYRN----------LADPEAEQLRRMIVNDGLKATIKKISRLEG----------KLLNEVVAAYES----------------
185 UniRef50_D1AJ18 Mannitol-1-phosphate 5-dehy... 243 1e-62 1 15.3% 27:450 4:364 --------------------------AVHFGAGNIGKGF----IGDLLHDSGFYITFVEV----NDAVVQSINRTNS-YDIYVID-KNYEKRTINNVSALSSGEEE--------------------ITEA------------ILDADMVTTSVWADNLAKVAPVIAKGLQKRIDNKKEKLNILACENALYATDILKKEILKNLKADESEL----NNYACFPNVSVDR------------LALNIIKDGEPAVEIDSSFELVIEKNKLVNPDTEPIKGAIYAENLTMYLERKLYIVNCGHAAAAYLGFLKGYKIVQDALKDKEILEEVLGAMNESAAVLQKKFGfdLQKFIQKNIKRFTSEAVKDDILRVGRSPIRKltDRLVAPALGCIEYNYETKYLSKIIAAVFHYENPNDEQ----------AVILKKYLDENGIEKSITNFTKIQK--------------------------------------
186 UniRef50_B6W7M3 Putative uncharacterized pr... 242 2e-62 1 16.7% 27:474 4:385 --------------------------AIQFGAGAIGRGLLGKIIH--------DSGYELVFVDVFDKIVDQINE-DG-YVGLELMDHDNEAIKLDKVSALCSTKTEDLEKIYEKIA----------------------------QADIITTSVRVENLDSTSKILVKGLEK-KEANSPKVDIMAFENAFRASDILKNHILENSNFKEEDL----DKLATFPNTVTDRIV------------QNKMVDGRSVVEISDDFEAVIEQTKLKDPKSKPIKDAEYTQNIDEELERKLFLVNGVHAATSYFGHHKGYTMMDEAFGDEEILSDVKKLMEESSEVLIKKYGFdlDKFKEAKLNRFLKTASHDEVARVARDPQRKLGkrLVSPAISAYDNNSSYDYLAKAIAYAFKYDNKEDEK----------AMEIQEYIKENGIEKAIEKYTEITK------KQRPGLFEKILDQYKKID--------------
187 UniRef50_B1KB28 Mannitol dehydrogenase doma... 240 6e-62 1 22.6% 23:385 1:352 ----------------------MTPPILQFGTSRFLLAHVDLFVSQALDDGNAMGGIGIVQTTGnrARIDALRAT-GRYPVRIRGRERgeVVECRAVQRAWDAERDWAE--IRAAAIETVRVIVSNTGDAGYRPDPRDAVDLLAQP--------AHAPHGFPAKLLALLHARWqrPDDGVSILPCELVTNNGDTLRDIVLGLARQwpDAFTDYLSSRCVWVNSLVDRIVSEPLH--------------PVGAIAEPYALWAIERR-AGTALPCTHAQIVVTDDLRSHERLKLFFLNLGHSWLAEQWLAAGreTVLDAMNDARLRDGLEAVWRDEVTPVFVALgdTAERYVESVRERFLNPFLAHRIADIAVNHREKVARRIEPLL-------------------------------------------------------------------------------------------------------
188 UniRef50_A7IBN9 Mannitol dehydrogenase doma... 240 7e-62 1 23.9% 23:403 1:370 ----------------------MSGRIIQFGTSRFLQAHVDLFVHEARQAGQAVGPICIVQASGAADRAGRVAAFggGYPVIIRGIEKGERIevTSVDRGLSAAQD-WQALSDLFAK-DADIIVSNTADAGYEIAAADRGPA---------LLAGGVPVSFPGKLTALLHRRWRQSGRGLTVLPCELINRNGRVLSAAVAALAPeaPEAFLAWLEAEVIFADTLVDRIVS--------QALEPIGA------VAEPYALWVIERR-PGLDLPFTHPSVVLADDLEPFERLKLHILNLGHTVLADIwrRDPGETVREILADADVRGRLDDVYRHEVLPGFAAHGmeAQRYVATTLERFLNPFLDHRIADIAQNHATKVDRRITAFLSWWAEAggATPTLDVVIA-------------------------------------------------------------------------------------
189 UniRef50_Q89A37 Mannitol-1-phosphate 5-dehy... 240 9e-62 1 17.2% 27:450 3:370 --------------------------ALHFGAGNIGRGFIGP----LLLKSGFNLTFVD----NNQAIVDAInhQKYDITVV-----GNNFSYITTVKKV-----------------------------KAIYINDPNIYFKIAKINVITISVGVHAINSLVVFFEKLIRYKIETNdvFLTIIACENVFRCASKLKENIKIL---LPGIYHKYLDKNISFVDSVVDKIVCPNDKNNSDDI--------NLSVKVEKFSEWIVdtQFKHDRP--NIIGMIYSNHLDAFFERKLFTLNTGHAIAAYLGLLIGYKNIYQAILDPLIFNIVYGAMKESGMVLIRKYNfeHKNYILKILSRFKNIYLTDSLKRVGRNPLQKLKkrLISPLIDTIKYNLPNANLMKGIAAALCY----------IDEKDIEAKKLRNMIINKGIKYVLSKISSLDS--------------------------------------
190 UniRef50_B3W862 Mannitol-1-phosphate 5-dehy... 237 1e-60 1 16.3% 21:475 2:387 --------------------KTMKKSAVHFGSGSIGRGF----IGKLLHDSGYQVTMLDV----DDSIISSINAIGG-YDLYLI-NHNYQKVFIDQVS-AINSLKDTQGAIDAI-----------------------------KDADIITTAVLATNLEKIAPILSKGLKARLQLRKAKINILACENLENNSGVLRKKVLALGEIKENDL----ESIAAFPDTEVDRLVLKSERNG-----------EPAIDIGDEF-ELVVDKTKLVNPGVEPIKNAFYTTDIHKYFERKLFIINTGHCWAGYVGHVYGYKVIQDVFANKPLLRATREAMKESAVLIEKKYGfdLDDYISFALNRFMTPGVVDQIARVSRNPIQKIgeRLVQPVQQLADRNLPYQQLVKGISAALLFDLDT----------DQQAIELQHYIEKNGVKQTIVHFTGI--------AEESVLFSQIMEHYNRFKQ-------------
191 UniRef50_Q2VSS2 Mannitol-1-phosphate dehydr... 234 4e-60 1 21.8% 54:406 5:340 -----------------------------------------------------DARIFVTFADINQTQIDQIN-QNKQYGVKIVG-DDSRVEIVKNIAAINSKDEN---AVIE----------------------------QVKNTDLITTAVGPNVLGFIAPLFAKALVARVESGNtpLNIIACENMVRGTTFFKGKIFEHLTA---EQQAEIEKVVGFVDSAVDRIVP--PAEQQAEIEKVVGfaDPLEVTVEEFSEWIVDQTQFKGDIP-NIKGMELTDNLMAFVERKLFTLNTGHLICAYLGKQAGVKWIKEAIAIEEIKTQVKATMEESGAVLIKRYGFDPqaYIEKILKRFANPYLNDDVNRVGREPIRKLSerLIKPLRGTLEYGLPYQNLVKGVVMAL----------------------------------------------------------------------------------
192 UniRef50_Q6AHH7 Mannitol-1-phosphate 5-dehy... 234 5e-60 1 18.7% 26:469 2:381 -------------------------KAVHFGAGNIGRGFVGLLLHEA--------GYEVVFADVNAELIEALAAADS-YDVRLVGDETVTKTVTG--FRALNSATAEDELVGEIAT-----------------------------ADVVTTAVGPRILRFVAPVIARGLGAR-ASGAPRLVVMACENAIGATDLLAAELMDGLQ--DGDTRDELAARAVFANTAVDRIVPAQDPAS------------GVDVTVEAFFEWVVDrpFAGAEPP--IPGAHFVDSLGPYIERKLFTVNTGHATTAYTGFLEGAATISEAIAKPSVLATVEAVLEETSAALTAKHGLdlAEYRAKILNRFRNPHLVDEVTRVGREPLRKLGrrFIGPASDYARygGAPSALLAAVGAALRFDLP----------GDSQSAELQQLLRKTEPGGIVTEVMGVEP--GDAL--YEPLVAVVRTA-------------------
193 UniRef50_C9CRE2 Fructuronate reductase n=1 ... 230 9e-59 1 41.9% 254:487 190:414 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CEPFRQWVIEDDFANGRPPFAEGGATLVTDVQPFEEMKLRLLNGAHTTLAWLGQLLGYQTVADCMADKELRALVRHLMLAEQAATlpLEGIDLAAYADELLKRFENTRLRHRLDQIASDSSQKMPQRLFAPIAANFEVKRDWSVSAVAVAAWIMGLR------SLPPVPDPRQDDLRRAALSDDP---VAGVLSLPSLVPDALRARAEFQTAISAAFDRL-QGGAKSAVTTTAK-
194 UniRef50_Q6GER8 Mannitol-1-phosphate 5-dehy... 227 6e-58 1 16.5% 26:473 2:367 -------------------------KAVHFGAGNIGRGFIGYILADNN--------VKVTFADVNEEIINAL-ATGHQYDVILADESKTTTRvvAAINSM-QPSEELKQAILEA--------------------------------DIITTAVGVN----ILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLG--------NNIHFANSAVDRIVPLQKNENI------------LDVMVEPFYEWVVEKDAWYGP---ELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAEtiTNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIgdRIIKPLAYLYNKDLERTGLLNTAALLLKYD----------DTADQETVEKNNYIKEHGLKAFLSEYAKV----------DDGLADEIIEAYNSL---------------
195 UniRef50_B9DTG2 Putative mannitol-1-phospha... 226 1e-57 1 15.7% 26:476 2:380 -------------------------KAVHFGAGNIGRGFIGNILH--------DSGYELLFVDMDKNLVQQI-HNDREYEIQILDFDQDPI-IIDNV---------------DAILGNSTELVI----------------EELVKADIITTSVGANNLKYLAQNMKNALLKRAELKTT-VTVIANENTINATDILSEEIFNICSEAERDKILSITN---FVNSAIDR------------QAMSKNYNGKSVALVEKYFEWVIEKNDYTKEIEGIIASAKFVEDLEPYIERKLFLVNAEHAAFAYLGKLFGYKTVQSSADNKDILNLVKRMTIENSRYfyNMDPVELESFISKTLLRHTNPKFSDEVERVGRNPIRKLgdRLISPFVKLTELSLPNICLTKVIAAALFF----------TDESDSESLQLQAMIAKEGVETVLEKICGLSEV----------LITQIMKEYNSIKSD------------
196 UniRef50_B3W722 Mannitol dehydrogenase-like... 225 3e-57 1 16.4% 25:450 2:367 ------------------------ATAVHFGAGKIGLGF----IGDLLHQSGYHIVFADVV----EKTVAQLRK-EKQYRLFLIDHDYQE-RIIDNV-DAVSSIQDPTG-------------VVEAIT----------------HADIVTTSVMASNLPKVAPLIAKGLKARLEKHLPKMTVMACENAIMGTDILKKAMLDSGEMTSEQL----EQAAVYPNTAVDRVVFDGHHQGQDGIE------------VGDAYELAIEREKLLDPNSEPIKGAEYVDNLEMYLQRKIYIINCGHAISAYLGQVHGYHTVQEVLHNERLLYQVKAAMAESAAALEAKYHfsLQDYIETmvKRMTTPGLSDPVTRVGREPIRKLsdRIIGPANECESFGLDNQYLLRGAACALLFHNPDDEQ----------AVEIQQFIKTHGIEKAITQYTKIQP--------------------------------------
197 UniRef50_B9CU65 Mannitol-1-phosphate 5-dehy... 219 3e-55 1 17.1% 26:476 2:370 -------------------------KAVHFGAGNIGRGFIGYILADNN--------IKVTFADVNEDIINALDS-EHQYDVILADEAKTTTRvvDAINSA-----KPSDQLKEAILEADLI-----TTAVGVNILP---------------------------IIAKSFAPYLKEKKNHVNIVACENAIMATDTLKKAIL--------DITGPLADYIHFANSAVDRIVPLQKNENI------------LDVMVEPFFEWVIEKDAWYGE---ELEHIKYVDDLTPYIERKLLTVNTGHAFLAYAGHFENKATILDSIEDKQIEAGLRQALSEtiTDQFDFSKNEQKQYVEKIIDRFNNPNLSDEVTRVGRGTIRKIgdRIIKPLTYLYNKGLEREGLVKAAALLLAY----DDNA------DQETVEKNNYIKEHGAKAFLKTYAKV----------DDQLADEIVKELELLQKK------------
198 UniRef50_B0P2D9 Putative uncharacterized pr... 211 4e-53 1 15.8% 26:429 2:365 -------------------------KAVMYGAGSIGRGFIGALFSE--------IGYEVVFIDVNDDVIHLINK-EKTYPQIIMNEEQ-PVHWIKNIRAV---DGKDPEAVSNEIAD----------------------------ADIMATALGAAVLEKVAPVIAQGLLKRWEKESSnlDILICENLMDADILLRDYLLK---ALPEDKHALFEKNVGLVETSIGRMVPPADPDLIPEDEH------PLAVRVEPYDFLPVDKAAFKGMIPEYKKIIPY-EPFHYYLERKLYVHNMAHVTTAFLGQYLNKTYIHEAAHDIYIQSIVRGCMTESCMMlyQVPFSKLNAHMNDLLHRFKNSYLKDTVTRVARDPMRKLqdRLIGAARSCESLHITPVYLSFAIALALSFMEGEDALNLMETveEPIAERI-----------------------------------------------------------
199 UniRef50_A3PGB6 Mannitol dehydrogenase, C-t... 207 8e-52 1 22.8% 21:398 2:357 --------------------SDIRTPVLQFGTSRFLQAHADLFFSEAAEPRA--VTVVQSSGDPARAARLGALAAPEGFPVVIRGLTDgtETRVTSVKRTLSTATD-WSALTAIFCS-EVELVISNTGDAGYQPGPADFDADFSQE------------MSFPAKLFQLLAARFAAGARPLTIMPMELVPENGRVLRDRLLAIgnRAPAALMDWIA-GLPFANSLVDRIVSEP--------------LEPAGAVAEPYALWAIERAPRIAAPCAHPA-VQLVDDLEEIERLKLHVLNLGHTSLVDFWKRRGGalVRELMDGPEGRALLE-LYETEVLPGfkGRGDEARAYLEVTLDRFRNPFLDHRIADIAQNHPQKAERRIGAFLDWVGRSGPDMPDL------------------------------------------------------------------------------------------
200 UniRef50_A8EUM4 HAD-superfamily hydrolase n... 195 4e-48 1 20.6% 53:475 243:660 ----------------------------------------------------FKAGIHGFGAIGGGYLSQIFLHWDG-YT--------RPEKITGASKNVL------LRDLINSSGKYTIKyiAYHQTIRGINIIDLNDREAIDKMYIESDIIALTLPESAIknIALGLKARYKKHDKKLTILIVMNKIGAKKYVKRHILKSLKTIIEdeATQIINNTHFCETVVNRMVSNIpsNALKQFKENLSEIDELNisSEPDI-LIYADNNSPILNTLRQ--VKTVSNIDIMQNIKNKLSNGTHAIIAWYSSLLGYKTIGQGIGDKRVYSLAKRIMENEIKPFLINETPELKSY---ILE-FINNFikDSCHRVGRDPLRKLQkrVLGNIFSAQNMDLKTQNLEFGVACAILYSLLVA------PSKDKEATKIKELYAKRNKVEDILCYDgfKPYKGLDKKIDAKLIKRIENKLEKIKT-------------
201 UniRef50_Q1H0J0 HAD-superfamily hydrolase s... 194 7e-48 1 18.4% 41:475 234:708 ----------------------------------------DAFPQTINN---MRAGIHGFGAMGGGYLAQIFSHWDG-YT--------RPYEIIGASNNAI------LRSLVNAFGKYDVHylAFHQTIDRIRLIDMADEAAVCEMYAVSEIIGLCLPESaaAMIAKGLVARYQNGAGPLTILVILNKLSGAAFVRRQVKemVRMLDEQRAEQIMAMAYFTETVVNRMVSKIPKEILLktQKALgmHQEPALLAEPGLGKIVsrHASHLNRALDQLGVTlvDNIAEIQAIKNRLLNGTHAIIAWYASLLGYQTIGQGMGDERVVMLVKRLVNNEIKPAMLQENPALAEYINTS---FVNSFikDPCRRIGRDPLRKLQrrIMGSIELAARHGIQTPMLEFGAALGILY------SLRLITPEDKECQRIKALFEENGAVADVLAFSGdkPYLGLDRQQDAALIERIAEHLRQLTD-------------
202 UniRef50_UPI0001B478FE Mannitol dehydrogenase doma... 192 3e-47 1 37.8% 1:185 10:195 LSNRTMSGLPSSVKVPAYDRSRITTGIAHLGIGAFHRAHQAAYTDAVLTSGSNEWGIVGVSLRRPDT-RDALQIQDELYTLAIRDGDSEKLQVIGSIQNILVAPEDP-QAVLDIMSHPDTRIVSLTITEKGYCRDAAVSGLDRSHPDIIYDLAHPAtpSASSQKHSGGGAPRERRRLPFFPVIIC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
203 UniRef50_B0P355 Putative uncharacterized pr... 185 5e-45 1 17.1% 20:475 6:399 -------------------RLKMKKELLVIGAGNIGRG----VIGGLFFESGYHLYIYDIM----EERMKQLKEQ-GTYLIERVGANNKRRVLV-----------DDFDVLD--------------------CSDTVDLIEHMKKVDLIACCVYEGAFQSICQNLKEAIEYRTEQEAAPLNILLCVNALGAPDYFETELAKLLQN-NPAASRYLKEKIGICQVMV--------GMAAMPSSEELIAEDAFAVTTKLDGHIGieEPFKGELPQVKQTGG--VQKGKAQIYRKVYTGNMKHCMLAFLGKAKGYTYIRDTYDDGWIEDCVLGAFFeaIQAEYQFDETDHQEWIDFIVEAPKNRNLKDAFTRVAADPKTKLSrrFVGPALLCMKHHILPFYLAKGIAYGFLY----------RDESDIASIEITNYVKEHGIEKAIEVYCG--------LTENeeLKQLIMAQYKEAEK-------------
204 UniRef50_A8RA68 Putative uncharacterized pr... 185 5e-45 1 15.1% 23:480 1:390 ----------------------MKKSIL-FGAGKIARGF----LGQLLYLSDFEITFVDV----YEPIVSVLNEKK-TYHVHVLGDESLDSD-VTHIKAYLF---DEKESIYHTFYESDIAFVS------------VGGNHLTDVAKSLADIFN-----------------RFGIQKKIKNIIVCENWRDAANTFKTAMLKFLNEENKNL---FEEFIGVSEAVLMR-TATQPDEELAKLY-------PQDVWVQNFWYLPIDGSRIKEAIP-KIQCVELLDEFGNFLTQKMYTNNTSNAVIAYSGYLLGYEILAEAANSLEISALLDDAYKEINQILVAELGVdqMEFSQKARAKYCDWTIVDKVIRHGKDPIRKLgdRLIAPCRMALKHGIYPKTLIDTIAKALYFD----------EPSDVEAVKLKMLRQQKGIEYVLQTVCG--------LDKTERLYHEILKSVEQIKEQGLVK--------
205 UniRef50_B0KG55 HAD-superfamily hydrolase, ... 180 8e-44 1 18.2% 51:485 242:710 --------------------------------------------------NQFRVGIHGFGAIGGGYLTQVFSHWDG-YT--------RPCEIIAAtsRMLRESVNAFGRYSVRYGATSFDQTIDNV--RMIDLDDDDAVimYTTAEIIGLSLPEQAIRNQAKVIAKGLLQRFERRGRELTLLIVLNKVGGAAFVRRHvaELALLCPPAIGKQVLEKTHFAETVVSRIVSKLSNDALVRQLrqNSLEDEPAVAtePDMPLYVegSDLLERLR----QVKTVPDIAQIQVIKNRLWNGPHAIVAWYASLLGHDSVGQGMGDARVCELAERLIRQEVGPAL------VAEymAEVVSRFADTFlkDPCARVGRDPLRKLQrrILSSIDLARKQGIETPALAFGAALAIHH---------ALRCKDDKALEAQAIRQvrDNGASVEAVLTHdrFPGLDPITDAQLISAISDAFRQYPQRDVANRLDDL---
206 UniRef50_UPI000190FD9C D-mannonate oxidoreductase ... 179 2e-43 1 49.1% 5:163 4:164 ----NIATAQVSVARPNWDKSRLVSRIVHLGCGAFHRAHQALFTHHLLEKSDSDWGICEVNLMPgaRLIANLKAQNLLYTVAERGAESTELKIIGSMKEALHPEFDGHAGILAAMARPETAIVSLTVTEKGYCTDPASGELDVNNPLIQNDLAHPQQPKSAIG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
207 UniRef50_D0NDP9 Putative uncharacterized pr... 178 3e-43 1 17.0% 30:459 38:440 -----------------------------IGSGRFLRC---VLVPTLRAAGSA----VVVAQTRGTSFASACAKAEGKYEVDTIQNDGsqTEVVEVEAVGSLGDAEGRAAFMQLPSKVslKFIGFGVTESGIV---------KGGPAIVD--------------LTELLYnfTTQPNNIVSVINTDNLPKNGDTIKKLVLKTEWKGQPsfRAYVTSNVHFHNTMVDRLTSHRAGDSLVPLTEPW----PTKTLVIEDVHGVLDANKLSVLPGLHiaGQLEQDHL-----LKLSIANAVHTAMVYLLALTRVKTTCDVLKYPEIRQYLDLLYANDVAPSLELRGieAQHTYDEWMSRVEHKHFGLDNFWVGQNAMLKYGVRLFSTVEANveKYRPSVFMAFATALILRYLTPTQSDSR----KEDGTSVFVGAMDSIQDRTPLYSVTEKTWVYANGLTAN-----------------------------
208 UniRef50_B1A1C6 Altronate oxidoreductase/ma... 174 5e-42 1 20.6% 272:475 8:218 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PFEKAgiIVTDNQAPYRTRKVRILNGAHTLMVPVGLLAGIPTVRENIEDATVGQFVNDALTQEIIPSLPAAEG-LTEFKDDVLDRFRNPFIQHYLKSISLNSFPKFKTRVLPSIVSYMEKEQkpAYLSKSFASLIKLYDPKNKVGFEAQDNADVVELLGTVWEEYRSeeLVKKVLSYDTLWEADLSVNTLLVEEVSKSLREIES-------------
209 UniRef50_Q4A9D2 Mannitol-1-phosphate 5-dehy... 172 2e-41 1 13.8% 26:416 2:323 -------------------------KVVHFGAGNIGRGLIA----KLYHQNQFEIIFVDV----NQNLVNDLNKNGFYY---VINFENGEKYKITNFQAIHL---NNKENLLKKLSSAD--IISTSIGAKNLVF-----------------------LKSIFAKLA-------KIEEKHKQIICFENGYRVSSYFKT-ILEKCQFWN------------FVDTTIDQIAPSSND---------------LNVYTETFSEIILEEKQQK----IKLKTVEYLENLDFFILRKLFFVNALHSGIAYFAYNLKFNFINEALNSVIIQNYIEK-MKeqQTVLIINPLIemNEYFETTIKRFKNPVLQDLVVRVARNPITKISkrFDLLLKYAKKSKISSEKLSitFAYILNFDWENDNQA------------------------------------------------------------------------
210 UniRef50_C9V541 D-mannonate oxidoreductase ... 172 4e-41 1 41.2% 312:488 2:180 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTVSQTMAAPGFKQLIKALMEIEIAPTLplEGFDLSSYQAALIHRFENHALHHLTSQIAMDGSQKLPQRLLNTIQERLDGGGSIDRLALGVAAWMRYVTGKDEAGTPIDVRDPLSGQLLDQTQGkaPDEIMDALLSFRQIFTARLAANELFREKLRLALGSLYAVGSAETVRRYAEI
211 UniRef50_Q5IMD1 Mannitol-1-phosphate dehydr... 168 3e-40 1 19.4% 33:305 1:218 --------------------------------GNIGRGF----IGKLLADAGIQLTFADV----NQVVLDALNAR-HSYQVHVVG----ETEQVDTVSGV-NAVSSIGDDVVDLIA----------------------------QVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGnsPLNIIACENMVRGTTQLKGHVM---NALPEDAKAWVEEHVGFVDSAVDRIVPPSASAT----------NDPLEVTVETFSEWIVDKTQFKGALP-NIPGMELTDNLMAFVERKLFTLNTGHAITAYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
212 UniRef50_B0MBC7 Putative uncharacterized pr... 168 4e-40 1 14.0% 31:480 8:384 ------------------------------GAGRLGKGFFGETFDNA------GWKIA--FLDKDPRVVEELKRT-GSYHV--------EVHRVDSinRTVSGYE-------------------------AYVCDENYSCMDalNTDVIMLPLYPKDFREAGHYLSKCFTEFYkqPEKKLTAICVTNKNY---LIPEIIESFKEKLPDDVKAWFDTNVA----VRDSIIRRGTDAQTHYATEIVTMAVASLLIQTPVYN-----DFSDVEW------LELNDQIETLKDLKVFAINGPHASTAFWGYLKGYKTIPDAEKDEEIAGIIYQaiLDMIMEEYDITKEELDH-----LENLPTPmiPDSIYRVAFDPIRKlgDRLTGAAQRCLKHGLPYEAIAKGMAAGFGYTEPEDEN----------AVKLQEEIKELGIEETVHKYTKLE--------KDSPILRKVVEEYEALKDRGLIK--------
213 UniRef50_C9AC43 Predicted protein n=1 Tax=E... 167 1e-39 1 12.8% 27:478 6:385 --------------------------VLIVGAGRLGKGFVG--------ETFFNAGWKLTFLDRDPRVIQELKKR-NYYDVKVHTTDDVYTTRVEGYEAVL---TDENYSVMDSFLSTDLLMMTL----------------------------YPQDFQASAEYLAKCFNKQYKAknSKKTLICLTNKNHitSHFRKCLL------DDDVRAWFDKNVVI----RDSIVRRSTDAEDSYSTD---------LVTTAVASLIIQGPVYSDFSDVEWLDVR--DNVEMLKDIKVFTINGPHAATAYYGYLKGYKDISSAQSDPEVSKLVKKVHD----ATLHAVLFEYPVTRDEIRekAKN-EMPDAIYRVAFDPIRKVGarFMGVITLCEKYGIDYGGIAKAIACAFAYD----------DPNDANALELQAEISSQGLSSTIAKYIGRH--------EGDQVVGEILKEYKKMEAQGI----------
214 UniRef50_C5J772 Mannitol-1-phosphate 5-dehy... 165 3e-39 1 17.7% 26:398 2:302 -------------------------KAVHFGAGNIGRGLIARIYQQNN--------IEMIFVDVNPDLVNNLNQQK-TYKIIEI-TSNQEFHISN-----FHALHVNDENLIEHLKSAD--FVSTSIG-----------------------VNNLAKLQPIFNKLSEV-----ETHLK--QIICFENGFQISSLFAK-MLKTNNFW------------TFVDVTVDQIIPNINKSS-------------LDVIVENHYEIVLNDLDQQHKLDF----VIYSKNLQYFAIRKFLLVNVLHSTLAYLGFRKGYKFIHETLQDSTILHFikKVLFSIVLKHSQNQNVDLESYFQTNISRFKNKELKDEITRVARNPITKIGkrFDILLQEAKKLHLDSNKL------------------------------------------------------------------------------------------
215 UniRef50_C0D448 Putative uncharacterized pr... 165 4e-39 1 16.4% 25:475 2:396 ------------------------EKVVVIGAGRSGRG----YVGELYDLEGYEITYADI----DQELVDRLNGQ-GYYTVFKIDEDgeEVRRITGY-RALHTIRDH-RAYIDA------------IVEADYV---STATFPDGFDAISDD-------------IVEALRERMKRGIkpMAITVGANYVGVYDYYSK---RIGDQLSGEEREYLNTYMPLVESIIRR-ASSYPTEEQKKV-------DELAIQGDCLNTLEVERneGHGLPKFFK----MVDNVKREMIIKIWIGNTLHCSYAYLGQYYHLHSSFEAAVNDYVSkyACEEAYNAVAKQLGLPMPRPVKEWQGIWTYYRNPSLQDTVLRIGADPIRKLSrrFIGPALMSLENGDVPVFICRNAAYGFVFANPE----------DPSACRLQEMIREQGIEKTIVDVCQL------DLTqdKVVYDLILQSYKEIIS-------------
216 UniRef50_P55800 Mannitol-1-phosphate 5-dehy... 165 4e-39 1 13.1% 28:410 4:325 ---------------------------IHFGAGNIGCGFIAPIL----------SSIV-----------------DHIYFV------DNNIDIVNKI---------NTQKLIKIHTSDSKKISITNIS-AWLLTDFINYKKTWNEVSLLTISIGIKNLKHIIYYVNQLIDYKIKNNQK-LIIMCCENGIRVSSLFKSYFSN------------LNNNIYFVDVLVDRIVSN-----------KNILNDYL--ECEDYYLWIVDKTQLPSDFK-QVPNLTYTTSFDIQITKKIYMLNALHCSLAWFVffNKYLYVYQALKNDKVVEFVNNYLNEVILVLNHKYNINLDeyKNQIIKRLNSNFIKDDLKRLARNTELKLSkrILTILDYAKDNNLKHDILLLSYQNGLEYLK------------------------------------------------------------------------------
217 UniRef50_B7G4T6 Predicted protein n=1 Tax=P... 159 2e-37 1 16.4% 30:414 40:420 -----------------------------LGTGRFLRS---VLVPALNSFSHS----VLVQTR-GRSFLEYMATQDgtFPVDTVLPSgdRYRCYGAFSWGRVEDKAAFYDVSRKTSGPSVIGVG--VTEAGLASSETQAMKDLYDfqDMWEERSLWKPALTPHK--------------KLCVIDMDNIPQNGDVLARHMNSLAQD-NARMLRFLADKVVFLNTMVDRITSHREGDPMVPKAEPV-----------PAKALVILDSEGDLPVAFHKmgVVVRSTRAELeaLKLRVANGTHTALAHILALTKRTMTddGVAGPLLLAYLDALVETQILAAGGASGLEPHATaqDWRSRLTHPYFGLSSFFITQNGAAKGGIRLGPTVLDLVTRSQTTqaMAFAWACLLRWLTPDRR--------------------------------------------------------------------------
218 UniRef50_B2HZL0 Predicted phosphatase/phosp... 153 1e-35 1 17.2% 40:451 234:685 ---------------------------------------QEPFPQSLNQLT---VGIHGFGAIGGGYIAQILSHWDG-YT--------KPKRIIASTRNSLFREanAFGTYSIRYgsYDERIENMTIVD---SDNEQQMLEMYTHSSLIALCLPEQAIEPESKIIAKGLYARFNSQLepLTFLIILNKVGAkkHLKEALLELTN--DEDVTEHILKEHYFCDTVVNRMVSKLSNQNlvEQEDQIEIEDCNKLNQEQLNQASieTDMpkGSPLLEKlqVVLVDQITDIQLIKNRLWNGVHAMLAWYASLMGYESIGVAMGDHLVKAFAENLIA-EVKQGLA---IVLPNYAKD-LDRMSQSFlkDPCQRVARDPLRKlnERVMASIAVNICHDLPYKNLLKGAALGYAYAIQFLEIEETKAV-----EQLQQQIQNLDLSTTQRRQLEAELV-------------------------------------
219 UniRef50_Q98PH2 Mannitol-1-phosphate 5-dehy... 153 2e-35 1 14.4% 26:450 5:347 -------------------------KALHFGAGNIGRG----LISDIYMKNNMDFALVDI----DKDLIEKLNKQKS-YS--IIDFQTNKVFQISNFKAFSIDQEDEIKKWIEQADFISTSIGWSN---------------------------------------LASLKKFFEnlKEKAQIICFENGYKISSFFQSILN--------------IDSNHFVNASVDKIIPNFKS-------------DSLDVYVESYYEIILEQKNESQK---KLNFVNYSTDLEAYINKKLFLVNAIHSTIGYLGYLKKYTYINEALNDQQILFKIKRliNEILSKEYLLFKVdlNDYLEKNLKRFSIKENQDLISRVARNPIQKLSkrYFLIYNLVKKHNLEIDILLEIYKSIFYYDNKMDKE----------SSKIQSTIENKSLAYALKKFSNLDQ--------------------------------------
220 UniRef50_UPI0001903370 D-mannonate oxidoreductase ... 140 1e-31 1 33.5% 307:476 1:172 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YIGGYEFIRDVMDDAALAALAYRHMHAAARTLDPVPGINLDDYANELIARFANKAIAHRTYQIAMDGTQKLPQRLLEPACEALAHGDRAETYAIAVAAWMRYAIGEHGNGERYELRDPRAAEIEALIAdrTGPAISAALFTLPGLFPKTLTEHRAWAQDVSDKLEILIQD------------
221 UniRef50_A8RA67 Putative uncharacterized pr... 134 8e-30 1 15.8% 130:408 62:312 ---------------------------------------------------------------------------------------------------------------------------------KAYTVDSKQGLDALAQADLVMISVGQKNLDSLVPLIQKALAIRQK---GDVDILTAEN----GVHTKNYLIPLCQ----DKRVHLAETIVFCTT--------------------LKQENSLDVFSEDLDYLPYDVVSLGHQLPYKHTVAE--KNLSSLMQRKIYTYNCLSAVVTYLGYYKGYEEYAKAANDSEITMCMDNILQKLNACICKEYEIDVDefSQMAVAKFQNKAIVDTIERNARDVDRKLgeRILAPLCILKKYGKQSDELLLVAACAVYY--------------------------------------------------------------------------------
222 UniRef50_P78008 Mannitol-1-phosphate 5-dehy... 131 4e-29 1 17.4% 24:379 3:285 -----------------------RINVLHFGAGNIGRGVILPIYQQ------NDFSIDLVEL--NQNTVNELQKQK-QYQVHYLDCDQSQL-----VNDFNTWNLKDEAKIIELMERADV--ISTSIGAK-----------------------NLASLKTLFDK--AKFHKRA-------IVLCFENGFRISSNFKNIL------------QLNNTQVNFVDVVIDTIAPNFEKKANF-----------LDIYCEKYSEIYAET------FPLEIKGVNQKNSLDRFIIKKLLLVNALHSVIGLLGFQQKLKYVHETLQVKSNLTFVEKLAQQIIDALCAEYPenLLSYGKNNLVRFANPKIQDLNTRLIREPLRKLNQ-------------------------------------------------------------------------------------------------------------
223 UniRef50_C4U352 Mannitol dehydrogenase C-do... 125 5e-27 1 16.5% 106:432 12:308 ---------------------------------------------------------------------------------------------------------DADLQLIDRLQSARGYDILLtiDEQ--QHIPLAAALHPADPQLQEWLAQATVITTSVRK--ENLHHVASanCAPKTVICCENIEQSGAFFA----SLLQEAGVDDQHW-----SLPDCMVDRICSSHWPQTLEIEAESYGS-----ICVQALENAIIPDKF------------EITENIAARFQEKRILVNTYADGISFIGRAMGLEFLYQAAADQRINHLIDDYmyLQQVCHLSPQHLDTMEQRH--RQRLANTAIKRPLDTVARNFLAKigERFIYPLIELARRDINIDRAIPFVNALI--------NGWAMQQENPSQARQQAL--------------------------------------------------------
224 UniRef50_C6N2H1 Putative uncharacterized pr... 121 6e-26 1 20.4% 28:341 24:336 ---------------------------IH-GGGNIGLGLMADVINRSNFLEPYQ-----IIATSNDITFNTLINGNHQFRLQHIGADEGDDTVVSHITMTQRNHTD----IVKLYTD---------TTE------------------IIALCLTQNAFDESSESIAQGLINRYKQSKSNLTVL----VLMNRHHCDKYVRETISFKIGELIdeILERIEFIPTVSDRIVSKIPVEIVkeLKQQlgYDDSGTLETE--INEIIEDPnfNAEIPfeLSSIDGVEDLDILAVIKDKYINGPHAILAWVSALFNCVTIAQGINYPGMKNYIASLMDVEIAPTLKK---------------------------------------------------------------------------------------------------------------------------------------------------
225 UniRef50_Q0FE81 Mannitol-1-phosphate 5-dehy... 105 4e-21 1 14.3% 25:415 2:320 ------------------------VKALIVGAGAIGRGYVPW------ELKNFEITFFD----GNDQLATSLRER-GVY--KTFMSFGDRLDVMDVDSRLAFSDLN---------------------------------EIDLEVFDIAFVCVGPRNVEKLPKELGKLTCK----------IFSLENDPYTVKILQGHLGK--------------DDIYF--GVPDVIASLTASTENLEL-------DPNALHTENGV-LYLEDhdITDCLKDLTPGIHWIdqMKSEWDAKLYLHNTPHCIAAFYGYLFECKYVHEALAIEEVSIILEGVVDEILQMLKILTNHdmEAYAKKEIRRFSNNLLFDPVIRVAREPIRKlgGRLLGALRMCISAGISPVNLTKGIVAALKYNEKNDPD-------------------------------------------------------------------------
226 UniRef50_B1EK89 Mannitol dehydrogenase C-do... 103 2e-20 1 17.8% 221:439 14:212 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDCMVDRICSSCWPASTLIEAESWgqKLEGATTVQKFEQ---------------------VENITLRFQEKRILVNTYADGISFLGLAAGKQYLYQAAESEEIRLAMDNYMQLMKLYLCQECHLDAN-YLEKMAerLCNPHIKRSLESVARNFLQKIgeRFIYPLTVLQQRGVDIQP-------AISFLN-VLINGWANAQSEPQLARQQALASLNVAE-------------------------------------------------
227 UniRef50_C0VS89 Putative uncharacterized pr... 90 2e-16 1 23.5% 372:486 28:139 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DASDRIPKWLLPVVRENLKHDRKVTLSAAIIASWARYTEGVDEEGEPITIVDRMADRLHATAQGN--KDNIFAFLEDEEVFGEE-AHDERFRKPYAAVLESLHEIGSAKTVEKLI--
228 UniRef50_O96437 Mannitol-1-phosphate dehydr... 88 7e-16 1 14.4% 1:305 151:421 LPVVQLAEVLQRDKQPKGPHKLLPTPHLHFGAGKLGCGLV---LQAMLRSNVED---LVVLQRQSEDFEPLLSAAKReiPVFVNGEKVCEL--------LVYVHPNEIEELIQKLENKKLQNSKstSTHLVLTNDSELALKLAKAAKSLSCSLGPAMETALLPLLSQL-------PDTPKtlYACEN-------------DHAAV--ARLKEQLQQKVLVLPCMVDRIC-----------AARNIFADKIEVSAEPYEGEIveRPQFAPPPPFGGPNVhlRAAAHYLCQRKIGLVNGMHTTLAFL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
229 UniRef50_D0RMY4 Mannitol-1-phosphate 5-dehy... 81 9e-14 1 13.1% 23:320 1:217 ----------------------MSTKILIYGAGAIGRGFLAYKFSN----ERYELSFVD----KNRRLIELLKKRDFFYSVC-----------IKKKNYKFKKIFFKDAFYIDEI-------------------------IDIKKYDFVFCCVGPNQSYEIAKNFSKA-----------KNVISCENDIN-------TVEGIKNLSN-------NNNIFfpDV----ITSNTASPNLLK-------KDELTIVSE-DGELILE--NLKKFKKLKEAKKVSKSIFKMHWYAKFFIHNAPHALLAYLGWMKKYKFIHEAMAD------------------------------------------------------------------------------------------------------------------------------------------------------------------------
230 UniRef50_UPI0001C36157 fructuronate reductase n=1 ... 76 2e-12 1 21.2% 10:89 16:101 ---------RAGIGLPSYdrTTEAPVWVHFGIGNIFRIFIGSIADRLITDGLMDRGIVCVETFDYETIDRIYKPYDNLCLSVILHNDGS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
231 UniRef50_UPI0001AEC5E5 D-mannonate oxidoreductase ... 72 5e-11 1 25.0% 373:476 1:102 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSAKLPVFLFPTVRDNLAANRDTDISALVVACWAFydRHASQDGKSLEINDVLADKLHNAASNNQIDSL--SFLMLEEVFGK-LVDEARFTASFQGFVERLYQQ------------
232 UniRef50_C1N0F1 Predicted protein n=1 Tax=M... 41 0.088 1 14.2% 187:474 219:555 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLPDVEDETRPVLYACENDHseKLQFALRTKVEAVPCMVDRIctVSDDAKTVNVTAE-GHEGSIVVLNQPESA---DGKKEQGPLAGDFVQNPENEADSSYLYRklLTVNGMHTVIAflAllLSDETVTDEQRAEIWsaQVLVLMWEHGIPtmRVHGQdlLDQLRTTLDRFF--TIEDSTARvgGGVSLRYEGRLLPTYeeLLTAGWTPDCavLLKQAGLELESLQTDLQMLVDEARPFAAVDKRARAMKELEEAMKEEQARSPHTGpgLPPVEEVRAKFQESFEIIQ--------------
consensus/100% ........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
consensus/90% ...........................h.hG.G.hhhs..................h..............h......h...............t.....................................................................h..hh..h.......h.hhsh-.h..ss..htt.h.t..............t...h..shlDphss.......................h-.h..hhlpt............th.h..ph..h..hKhhhlNs.Hs.hs..u.h.tht.h.p.htt..h...h.thh.......h.....p..ta.t.hhtRh.s..h.c...pls.ps..Kh..hhh..h....t.t.........hs.hh.h...............................................................................
consensus/80% ..........................hlphG.GshhRua....htth......ththh.h.....t.h.p.ht.tpt.a.l...s.tttp..hltsh.thh.......tthhthh........................................t...th.shlsthl..Rhttt..shsllss-.h.tsuthhpthlhthht.h..thhthhttth.FssshVDRIsst...t............t.h.h.sE.a..hhl-t...tt...ht..sh.hstsltsa..hKlhhlNssHshhshhu.hhGhphltpshts..h.thhpthh.pphh.hh...t.ph.tahttlhtRFtNshltc.h.pluhss.tKh..Rhh.sh..hht.t...thhhhshAshhha..............c.....h.t.h.t.t.......hht..................h....................
consensus/70% ......................thlphG.GshhRua.shhhpph.ttt..phslhsht....tthhptlttpsthYslh.hs.pttphphlssltphh.s..p..tthhthhtt.ththl..shTEtuh.................ts..t.t..tsh.uhlsthLhtRhpttttshsllsC-Nh.tNGphhcphlhphht.hs.thhtaltptstFssohVDRIsPshstt.h..h.t..thtD.h.lhsEsah.WllEsp..tsp.shphsGs.hsssltsapphKlhhLNusHshhuhhuhlhGhphlt-shtc..htthlpthh.pphhshl...t.-httahptllpRFtNshltcph.pluhss.pKh..Rhlsshhthhttst..thhshslAuhhhah.............Ds...thtthhttts.tt.htthht.t......h.t...hht.l.t.ht.h.............
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