Phyre 2 Results for P0AA41

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Email | l.a.kelley@imperial.ac.uk
Description | P0AA41
Date | Thu Jan 5 11:11:52 GMT 2012
Unique Job ID | a3bde3b0c6bec88a

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c1v9fA_
Top template information
PDB header:lyase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d; PDBTitle: crystal structure of catalytic domain of pseudouridine2 synthase rlud from escherichia coli
Confidence and coverage
Confidence: | 100.0% | Coverage: | 86%
223 residues ( 86% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | L | E | I | L | Y | Q | D | E | W | L | V | A | V | N | K | P | S | G | W | L | V | H | R | S | W | L | D | R | D | E | K | V | V | V | M | Q | T | V | R | D | Q | I | G | Q | H | V | F | T | A | H | R | L | D | R | P | T | S | G | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | L | L | M | G | L | S | S | E | A | G | R | L | L | A | Q | Q | F | E | Q | H | Q | I | Q | K | R | Y | H | A | I | V | R | G | W | L | M | E | E | A | V | L | D | Y | P | L | V | E | E | L | D | K | I | A | D | K | F | A | R | E | D | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  | ? |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | G | P | Q | P | A | V | T | H | Y | R | G | L | A | T | V | E | M | P | V | A | T | G | R | Y | P | T | T | R | Y | G | L | V | E | L | E | P | K | T | G | R | K | H | Q | L | R | R | H | L | A | H | L | R | H | P | I | I | G | D | S | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | H | G | D | L | R | Q | N | R | S | G | A | E | H | F | G | L | Q | R | L | M | L | H | A | S | Q | L | S | L | T | H | P | F | T | G | E | P | L | T | I | H | A | G | L | D | D | T | W | M | Q | A | L | S | Q | F | G | W | R | G | L | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260
Sequence |  | P | E | N | E | R | V | E | F | S | A | P | S | G | Q | D | G | E | I | S | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c1v9fA_ |

### PDB 1v9f chain A

Region: 2 - 237
Aligned: 223
Modelled: 236
Confidence: 100.0%
Identity: 28%
PDB header:lyase
Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d;
PDBTitle: crystal structure of catalytic domain of pseudouridine2 synthase rlud from escherichia coli

Phyre2
2 |
| d1v9fa_ |

### PDB 1v9f chain A

Region: 2 - 237
Aligned: 223
Modelled: 236
Confidence: 100.0%
Identity: 28%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase RsuA/RluD

Phyre2
3 |
| c1qyuA_ |

### PDB 1qyu chain A

Region: 2 - 237
Aligned: 223
Modelled: 236
Confidence: 100.0%
Identity: 27%
PDB header:lyase
Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d;
PDBTitle: structure of the catalytic domain of 23s rrna pseudouridine2 synthase rlud

Phyre2
4 |
| d1v9ka_ |

### PDB 1v9k chain A

Region: 4 - 234
Aligned: 219
Modelled: 228
Confidence: 100.0%
Identity: 34%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase RsuA/RluD

Phyre2
5 |
| c2i82D_ |

### PDB 2i82 chain D

Region: 2 - 224
Aligned: 205
Modelled: 217
Confidence: 100.0%
Identity: 36%
PDB header:lyase/rna
Chain: D: PDB Molecule:ribosomal large subunit pseudouridine synthase a;
PDBTitle: crystal structure of pseudouridine synthase rlua: indirect2 sequence readout through protein-induced rna structure

Phyre2
6 |
| c1vioA_ |

### PDB 1vio chain A

Region: 2 - 183
Aligned: 151
Modelled: 170
Confidence: 100.0%
Identity: 21%
PDB header:lyase
Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a;
PDBTitle: crystal structure of pseudouridylate synthase

Phyre2
7 |
| c1kskA_ |

### PDB 1ksk chain A

Region: 4 - 183
Aligned: 151
Modelled: 168
Confidence: 100.0%
Identity: 19%
PDB header:lyase
Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a;
PDBTitle: structure of rsua

Phyre2
8 |
| c2omlA_ |

### PDB 2oml chain A

Region: 7 - 188
Aligned: 164
Modelled: 180
Confidence: 100.0%
Identity: 19%
PDB header:isomerase
Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase e;
PDBTitle: crystal structure of e. coli pseudouridine synthase rlue

Phyre2
9 |
| c2olwB_ |

### PDB 2olw chain B

Region: 11 - 183
Aligned: 155
Modelled: 173
Confidence: 100.0%
Identity: 19%
PDB header:isomerase
Chain: B: PDB Molecule:ribosomal large subunit pseudouridine synthase e;
PDBTitle: crystal structure of e. coli pseudouridine synthase rlue

Phyre2
10 |
| c3dh3C_ |

### PDB 3dh3 chain C

Region: 3 - 183
Aligned: 148
Modelled: 155
Confidence: 100.0%
Identity: 20%
PDB header:isomerase/rna
Chain: C: PDB Molecule:ribosomal large subunit pseudouridine synthase f;
PDBTitle: crystal structure of rluf in complex with a 22 nucleotide2 rna substrate

Phyre2
11 |
| d1kska4 |

### PDB 1ksk chain A domain 4

Region: 10 - 181
Aligned: 143
Modelled: 172
Confidence: 100.0%
Identity: 18%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase RsuA/RluD

Phyre2
12 |
| d1vioa1 |

### PDB 1vio chain A domain 1

Region: 7 - 183
Aligned: 146
Modelled: 165
Confidence: 100.0%
Identity: 21%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase RsuA/RluD

Phyre2
13 |
| c2gmlA_ |

### PDB 2gml chain A

Region: 8 - 181
Aligned: 141
Modelled: 148
Confidence: 100.0%
Identity: 21%
PDB header:isomerase
Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase f;
PDBTitle: crystal structure of catalytic domain of e.coli rluf

Phyre2
14 |
| d1k8wa5 |

### PDB 1k8w chain A domain 5

Region: 9 - 90
Aligned: 69
Modelled: 82
Confidence: 97.7%
Identity: 20%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase II TruB

Phyre2
15 |
| d1sgva2 |

### PDB 1sgv chain A domain 2

Region: 8 - 90
Aligned: 70
Modelled: 83
Confidence: 97.6%
Identity: 27%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase II TruB

Phyre2
16 |
| d2apoa2 |

### PDB 2apo chain A domain 2

Region: 9 - 90
Aligned: 69
Modelled: 82
Confidence: 97.5%
Identity: 22%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase II TruB

Phyre2
17 |
| d2ey4a2 |

### PDB 2ey4 chain A domain 2

Region: 8 - 91
Aligned: 71
Modelled: 84
Confidence: 97.5%
Identity: 23%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase II TruB

Phyre2
18 |
| c2ey4A_ |

### PDB 2ey4 chain A

Region: 9 - 91
Aligned: 70
Modelled: 83
Confidence: 97.4%
Identity: 23%
PDB header:isomerase/biosynthetic protein
Chain: A: PDB Molecule:probable trna pseudouridine synthase b;
PDBTitle: crystal structure of a cbf5-nop10-gar1 complex

Phyre2
19 |
| d1r3ea2 |

### PDB 1r3e chain A domain 2

Region: 9 - 90
Aligned: 69
Modelled: 82
Confidence: 97.4%
Identity: 20%
Fold: Pseudouridine synthase
Superfamily: Pseudouridine synthase
Family: Pseudouridine synthase II TruB

Phyre2
20 |
| c3uaiA_ |

### PDB 3uai chain A

Region: 8 - 90
Aligned: 70
Modelled: 82
Confidence: 97.1%
Identity: 26%
PDB header:isomerase/chaperone
Chain: A: PDB Molecule:h/aca ribonucleoprotein complex subunit 4;
PDBTitle: structure of the shq1-cbf5-nop10-gar1 complex from saccharomyces2 cerevisiae

Phyre2
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71 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c1v9fA_ |
|  | 100.0 | 28 | PDB header:lyase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d; PDBTitle: crystal structure of catalytic domain of pseudouridine2 synthase rlud from escherichia coli
2 | d1v9fa_ |
|  | 100.0 | 28 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase RsuA/RluD
3 | c1qyuA_ |
|  | 100.0 | 27 | PDB header:lyase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase d; PDBTitle: structure of the catalytic domain of 23s rrna pseudouridine2 synthase rlud
4 | d1v9ka_ |
|  | 100.0 | 34 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase RsuA/RluD
5 | c2i82D_ |
|  | 100.0 | 36 | PDB header:lyase/rna Chain: D: PDB Molecule:ribosomal large subunit pseudouridine synthase a; PDBTitle: crystal structure of pseudouridine synthase rlua: indirect2 sequence readout through protein-induced rna structure
6 | c1vioA_ |
|  | 100.0 | 21 | PDB header:lyase Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a; PDBTitle: crystal structure of pseudouridylate synthase
7 | c1kskA_ |
|  | 100.0 | 19 | PDB header:lyase Chain: A: PDB Molecule:ribosomal small subunit pseudouridine synthase a; PDBTitle: structure of rsua
8 | c2omlA_ |
|  | 100.0 | 19 | PDB header:isomerase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase e; PDBTitle: crystal structure of e. coli pseudouridine synthase rlue
9 | c2olwB_ |
|  | 100.0 | 19 | PDB header:isomerase Chain: B: PDB Molecule:ribosomal large subunit pseudouridine synthase e; PDBTitle: crystal structure of e. coli pseudouridine synthase rlue
10 | c3dh3C_ |
|  | 100.0 | 20 | PDB header:isomerase/rna Chain: C: PDB Molecule:ribosomal large subunit pseudouridine synthase f; PDBTitle: crystal structure of rluf in complex with a 22 nucleotide2 rna substrate
11 | d1kska4 |
|  | 100.0 | 18 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase RsuA/RluD
12 | d1vioa1 |
|  | 100.0 | 21 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase RsuA/RluD
13 | c2gmlA_ |
|  | 100.0 | 21 | PDB header:isomerase Chain: A: PDB Molecule:ribosomal large subunit pseudouridine synthase f; PDBTitle: crystal structure of catalytic domain of e.coli rluf
14 | d1k8wa5 |
|  | 97.7 | 20 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB
15 | d1sgva2 |
|  | 97.6 | 27 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB
16 | d2apoa2 |
|  | 97.5 | 22 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB
17 | d2ey4a2 |
|  | 97.5 | 23 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB
18 | c2ey4A_ |
|  | 97.4 | 23 | PDB header:isomerase/biosynthetic protein Chain: A: PDB Molecule:probable trna pseudouridine synthase b; PDBTitle: crystal structure of a cbf5-nop10-gar1 complex
19 | d1r3ea2 |
|  | 97.4 | 20 | Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB
20 | c3uaiA_ |
|  | 97.1 | 26 | PDB header:isomerase/chaperone Chain: A: PDB Molecule:h/aca ribonucleoprotein complex subunit 4; PDBTitle: structure of the shq1-cbf5-nop10-gar1 complex from saccharomyces2 cerevisiae
21 | c2apoA_ |
| not modelled | 97.0 | 21 | PDB header:isomerase/rna binding protein Chain: A: PDB Molecule:probable trna pseudouridine synthase b; PDBTitle: crystal structure of the methanococcus jannaschii cbf52 nop10 complex
22 | c1k8wA_ |
| not modelled | 97.0 | 20 | PDB header:lyase/rna Chain: A: PDB Molecule:trna pseudouridine synthase b; PDBTitle: crystal structure of the e. coli pseudouridine synthase2 trub bound to a t stem-loop rna
23 | c1sgvA_ |
| not modelled | 96.6 | 27 | PDB header:lyase Chain: A: PDB Molecule:trna pseudouridine synthase b; PDBTitle: structure of trna psi55 pseudouridine synthase (trub)
24 | c1ze2B_ |
| not modelled | 95.1 | 28 | PDB header:lyase/rna Chain: B: PDB Molecule:trna pseudouridine synthase b; PDBTitle: conformational change of pseudouridine 55 synthase upon its2 association with rna substrate
25 | c3n1tE_ |
| not modelled | 24.0 | 42 | PDB header:hydrolase Chain: E: PDB Molecule:hit-like protein hint; PDBTitle: crystal structure of the h101a mutant echint gmp complex
26 | d1rzya_ |
| not modelled | 22.8 | 25 | Fold:HIT-like Superfamily:HIT-like Family:HIT (HINT, histidine triad) family of protein kinase-interacting proteins
27 | c2zodB_ |
| not modelled | 21.9 | 23 | PDB header:transferase Chain: B: PDB Molecule:selenide, water dikinase; PDBTitle: crystal structure of selenophosphate synthetase from2 aquifex aeolicus
28 | c3l7xA_ |
| not modelled | 21.4 | 33 | PDB header:cell cycle Chain: A: PDB Molecule:putative hit-like protein involved in cell-cycle PDBTitle: the crystal structure of smu.412c from streptococcus mutans ua159
29 | d1emsa1 |
| not modelled | 20.0 | 17 | Fold:HIT-like Superfamily:HIT-like Family:HIT (HINT, histidine triad) family of protein kinase-interacting proteins
30 | c1mzwB_ |
| not modelled | 18.7 | 31 | PDB header:isomerase Chain: B: PDB Molecule:u4/u6 snrnp 60kda protein; PDBTitle: crystal structure of a u4/u6 snrnp complex between human2 spliceosomal cyclophilin h and a u4/u6-60k peptide
31 | d1kpfa_ |
| not modelled | 16.6 | 25 | Fold:HIT-like Superfamily:HIT-like Family:HIT (HINT, histidine triad) family of protein kinase-interacting proteins
32 | d1fita_ |
| not modelled | 15.3 | 18 | Fold:HIT-like Superfamily:HIT-like Family:HIT (HINT, histidine triad) family of protein kinase-interacting proteins
33 | c3o0mB_ |
| not modelled | 15.0 | 25 | PDB header:hydrolase Chain: B: PDB Molecule:hit family protein; PDBTitle: crystal structure of a zn-bound histidine triad family protein from2 mycobacterium smegmatis
34 | c1emsB_ |
| not modelled | 14.7 | 17 | PDB header:antitumor protein Chain: B: PDB Molecule:nit-fragile histidine triad fusion protein; PDBTitle: crystal structure of the c. elegans nitfhit protein
35 | c2zauB_ |
| not modelled | 13.0 | 24 | PDB header:transferase Chain: B: PDB Molecule:selenide, water dikinase; PDBTitle: crystal structure of an n-terminally truncated2 selenophosphate synthetase from aquifex aeolicus
36 | d1guqa2 |
| not modelled | 12.2 | 25 | Fold:HIT-like Superfamily:HIT-like Family:Hexose-1-phosphate uridylyltransferase
37 | c3p0tB_ |
| not modelled | 12.0 | 33 | PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an hit-like protein from mycobacterium2 paratuberculosis
38 | d1qwga_ |
| not modelled | 11.1 | 14 | Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA
39 | d2oika1 |
| not modelled | 10.2 | 50 | Fold:HIT-like Superfamily:HIT-like Family:HIT (HINT, histidine triad) family of protein kinase-interacting proteins
40 | c3lb5B_ |
| not modelled | 10.1 | 23 | PDB header:cell cycle Chain: B: PDB Molecule:hit-like protein involved in cell-cycle regulation; PDBTitle: crystal structure of hit-like protein involved in cell-cycle2 regulation from bartonella henselae with unknown ligand
41 | c2jv2A_ |
| not modelled | 10.0 | 7 | PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein ph1500; PDBTitle: solution structure of the n-terminal domain of ph1500
42 | d2aaaa1 |
| not modelled | 10.0 | 29 | Fold:Glycosyl hydrolase domain Superfamily:Glycosyl hydrolase domain Family:alpha-Amylases, C-terminal beta-sheet domain
43 | c1xquA_ |
| not modelled | 9.6 | 42 | PDB header:hydrolase Chain: A: PDB Molecule:hit family hydrolase; PDBTitle: hit family hydrolase from clostridium thermocellum cth-393
44 | d1xqua_ |
| not modelled | 9.6 | 42 | Fold:HIT-like Superfamily:HIT-like Family:HIT (HINT, histidine triad) family of protein kinase-interacting proteins
45 | c3zrhA_ |
| not modelled | 9.4 | 31 | PDB header:hydrolase Chain: A: PDB Molecule:ubiquitin thioesterase zranb1; PDBTitle: crystal structure of the lys29, lys33-linkage-specific trabid otu2 deubiquitinase domain reveals an ankyrin-repeat ubiquitin binding3 domain (ankubd)
46 | d1gr0a1 |
| not modelled | 9.3 | 21 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
47 | c2lf6A_ |
| not modelled | 9.2 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:effector protein hopab1; PDBTitle: solution nmr structure of hopabpph1448_220_320 from pseudomonas2 syringae pv. phaseolicola str. 1448a, midwest center for structural3 genomics target apc40132.4 and northeast structural genomics4 consortium target pst3a
48 | d2zoda2 |
| not modelled | 8.4 | 17 | Fold:PurM C-terminal domain-like Superfamily:PurM C-terminal domain-like Family:PurM C-terminal domain-like
49 | d1vjpa1 |
| not modelled | 7.8 | 12 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
50 | c2do5A_ |
| not modelled | 7.8 | 35 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:splicing factor 3b subunit 2; PDBTitle: solution structure of the sap domain of human splicing2 factor 3b subunit 2
51 | c3ksvA_ |
| not modelled | 7.7 | 8 | PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: hypothetical protein from leishmania major
52 | c2oi2A_ |
| not modelled | 7.5 | 13 | PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: streptococcus pneumoniae mevalonate kinase in complex with2 diphosphomevalonate
53 | c2eo4A_ |
| not modelled | 7.4 | 36 | PDB header:hydrolase Chain: A: PDB Molecule:150aa long hypothetical histidine triad nucleotide-binding PDBTitle: crystal structure of hypothetical histidine triad nucleotide-binding2 protein st2152 from sulfolobus tokodaii strain7
54 | c3oj7A_ |
| not modelled | 6.9 | 33 | PDB header:metal binding protein Chain: A: PDB Molecule:putative histidine triad family protein; PDBTitle: crystal structure of a histidine triad family protein from entamoeba2 histolytica, bound to sulfate
55 | d1k8ga2 |
| not modelled | 6.8 | 27 | Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB
56 | c2lkyA_ |
| not modelled | 6.8 | 33 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of msmeg_1053, the second duf3349 annotated protein2 in the genome of mycobacterium smegmatis, seattle structural genomics3 center for infectious disease target mysma.17112.b
57 | c1u83A_ |
| not modelled | 6.6 | 14 | PDB header:lyase Chain: A: PDB Molecule:phosphosulfolactate synthase; PDBTitle: psl synthase from bacillus subtilis
58 | d1u83a_ |
| not modelled | 6.6 | 14 | Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA
59 | c3imiB_ |
| not modelled | 6.4 | 33 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hit family protein; PDBTitle: 2.01 angstrom resolution crystal structure of a hit family protein2 from bacillus anthracis str. 'ames ancestor'
60 | c3anoA_ |
| not modelled | 6.4 | 18 | PDB header:transferase Chain: A: PDB Molecule:ap-4-a phosphorylase; PDBTitle: crystal structure of a novel diadenosine 5',5'''-p1,p4-tetraphosphate2 phosphorylase from mycobacterium tuberculosis h37rv
61 | c1e0aB_ |
| not modelled | 6.4 | 28 | PDB header:signalling protein Chain: B: PDB Molecule:serine/threonine-protein kinase pak-alpha; PDBTitle: cdc42 complexed with the gtpase binding domain of p212 activated kinase
62 | c2kvcA_ |
| not modelled | 6.4 | 31 | PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: solution structure of the mycobacterium tuberculosis protein rv0543c,2 a member of the duf3349 superfamily. seattle structural genomics3 center for infectious disease target mytud.17112.a
63 | d1u2ca2 |
| not modelled | 6.2 | 27 | Fold:Dystroglycan, domain 2 Superfamily:Dystroglycan, domain 2 Family:Dystroglycan, domain 2
64 | d1jb7a2 |
| not modelled | 6.1 | 27 | Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB
65 | d1w91a1 |
| not modelled | 6.1 | 36 | Fold:Glycosyl hydrolase domain Superfamily:Glycosyl hydrolase domain Family:Composite domain of glycosyl hydrolase families 5, 30, 39 and 51
66 | d2al1a1 |
| not modelled | 6.1 | 11 | Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:Enolase
67 | d2guya1 |
| not modelled | 6.0 | 27 | Fold:Glycosyl hydrolase domain Superfamily:Glycosyl hydrolase domain Family:alpha-Amylases, C-terminal beta-sheet domain
68 | c2odbB_ |
| not modelled | 6.0 | 31 | PDB header:protein binding Chain: B: PDB Molecule:serine/threonine-protein kinase pak 6; PDBTitle: the crystal structure of human cdc42 in complex with the crib domain2 of human p21-activated kinase 6 (pak6)
69 | c1u1iC_ |
| not modelled | 5.7 | 16 | PDB header:isomerase Chain: C: PDB Molecule:myo-inositol-1-phosphate synthase; PDBTitle: myo-inositol phosphate synthase mips from a. fulgidus
70 | d1z84a2 |
| not modelled | 5.4 | 17 | Fold:HIT-like Superfamily:HIT-like Family:Hexose-1-phosphate uridylyltransferase
71 | d2hx5a1 |
| not modelled | 5.1 | 14 | Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0