>ss_pred
CEEEEEEECCEEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>ss_conf
92588860988999569880570789886436989999861578832792104777720389956999999999975418722899998767788534044043010677732899727998050048999876414443455677876899999567850689999998099367567678743343210114898020144485855688976899984999899999998397433551001454465788775579
>batch____
MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIGQHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDYPLVEELDKIADKFAREDKGPQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGRKHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLTIHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS
>UniRef50_A1WTN6(11-243:249) Pseudouridine synthase n=2 Tax=Ectothiorhodospiraceae RepID=A1WTN6_HALHL  E=1e-48 s/c=0.84 id=49% cov=85%
-LAILYRDERLIAVYKPAGLLVHRSNIDRDRD-VVLQRLRDQLGGHwVYPVHRLDRATAGVLVFGLDPDAASVLAAAFREQRIGKRYQAVVRGWVEAPGRIDRPLGAGRRGEG-------GAPQPAVTDYVPLAWTELPIPVSRYDTARFTRLALHPQTGRQHQLRRHMKAISHPILGDTTHGDGANNRFFREHFGARRLLLVATELVVPHPADGGAVRL-ATEPDAELQAI-----------------------------
>UniRef50_Q3JQ55(243-470:477) Pseudouridine synthase n=170 Tax=cellular organisms RepID=Q3JQ55_BURP1  E=3e-25 s/c=0.51 id=39% cov=85%
-FEILFEDDAIIVLNKPAGVAVHGGSGVAFGVIEQMRHARPH-AKFLELAHRLDRETSGILMLAKKRSALVGLHEQIRENRMDKRYFACVHGdWAADwgrRRVVKAPLF--------KYATPD-GERRVRVQEDGLPSHTVFNLVDRWPD--YALVEAELKTGRTHQIRVHLAHLGLPIVGDAKYGDFALNKALARANAvpsIKRMFLHAHRLRLAHPLTGEPLQFDAPLPAECRQFIDQL--------------------------
>UniRef50_Q5QZ45(94-312:315) Pseudouridine synthase n=2 Tax=Gammaproteobacteria RepID=Q5QZ45_IDILO  E=4e-24 s/c=0.52 id=37% cov=84%
---ILYEDDALMLINKPSGVAVHGGSGLQFGLIEGLRALRPK-EKSLELVHRIDRDTSGLLLVAKKRSVLRSLHEQLRNKEMNKQYLALVRGqWQKRVRSVEAPLKKNTLKSGERIVRVDAEGKASLTRFR---------IQQRYKEG--TLVEASPVTGRTHQIRVHALHAGHPIAKDPKYGDTDFDNTMS-RLGLNRLFLHAWQLRFLHPVTGKEVAFEAPLDDNLQQTLKQL--------------------------
>UniRef50_A9GIV4(108-339:350) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GIV4_SORC5  E=2e-23 s/c=0.48 id=41% cov=83%
-IPVLHEDDALLAIDKPAGLPVHPTARYHKSTVIKMMEA-ARPGERLFLAHRLDRETSGVLLLCRTPEADRTVKAQFEERTgVVKRYAAIAWGWPERDTFrVELPL--ELDD-ASRYKVKMRVAPPG----RGLASATACEVLGRRadPLTgrRYALVRCTLETGRQHQIRVHLAASGLPLVGDKLYGpDEGMFARGADgvltdddrrALELDRHALHAALLELTHPMTGERVRIEAPLSD-----------------------------------
>UniRef50_B6G997(7-227:227) Pseudouridine synthase n=1 Tax=Collinsella stercoris DSM 13279 RepID=B6G997_9ACTN  E=3e-23 s/c=0.50 id=40% cov=81%
-LRVLYRDPWLMAVDKPAGIIVHGDGTG-------APTLTDAVRAHLVASgeasasaaaqalQRLDRDTTGIVLFSLDKEAQPAFDRMIAERSIQKRYLAIVHGRFPAAKTMCQPLGR--DRHDSRRMRVSRTGKPAHTDAKRIAYAK---ADARAP--ERSLLAIDLHTGRKHQIRVHLAHAKFPLLGDSLYGG--PSCSGG-------LMLHASELSFTHPITGAPTHIQAPYPARFQRIMSQ---------------------------
>UniRef50_B5YAZ5(7-222:226) Pseudouridine synthase n=2 Tax=Dictyoglomus RepID=B5YAZ5_DICT6   E=5e-23 s/c=0.51 id=35% cov=80%
-LEVIYEDNHLLVVNKPAGILVQG---DITKSTTLLEISKAYIKEkykkpgNVFLAivHRLDKPVSGVVIFARNSKSAGRLSEAFRERKVEKEYIALCKGiFKVKKGTISESLLWVEKERKARVSQDDKS-KNAITHYEVLEEFK-----------NLSLVRLIPETGRKHQLRAHLSYIGHPILGDEKYG-------GGRIFK-DRIFLHCKKMAVPHPVRKDIMEFEAKIPDFWSEFL-----------------------------
>UniRef50_Q89AH2(95-314:315) Ribosomal large subunit pseudouridine synthase C n=5 Tax=Buchnera aphidicola RepID=RLUC_BUCBP  E=7e-23 s/c=0.50 id=31% cov=85%
---ILYEDNYFLILNKPSGMSVHSGSGINYGMIENLRILRPY-NRYLDLVHRLDRDTSGVLIIAKKRSILRNLHEQLREKKIKKKYVALVHGvWPDILKSISKPLLKTSSRKNKNIVKIDPKGKESITHFN---------IKKKY--TKNTLISITPITGRTHQIRVHLLHLNYPIVLDAKYGIKKLDYFIKNKFNINRLLLHAESINFFHPKRKKNILITAPLDYVFKTVLKNL--------------------------
>UniRef50_Q0F3G4(94-314:315) Pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F3G4_9PROT  E=1e-22 s/c=0.49 id=35% cov=85%
-IPVLYEDDSLLVVNKPAGMVVHGG---SGHEAGLIEALKQSRGlDDLRLAHRLDRDTSGVLLMAKHLDALRRLTESFRERDMQKTYFALIAGHPYAHAgRMSSNLAKGVVRGGERMVVDSEEGKASVTDYQVMIEYE----RHGFP---YAMVALNPHSGRTHQLRVQLQHEGHPILGDGKYGE-KAQLAAYKSLGGKGLMLHAWRLRFTHPVSGKSLECKAPWPDNWSALL-----------------------------
>UniRef50_Q492Q1(94-322:338) Pseudouridine synthase n=2 Tax=Candidatus Blochmannia RepID=Q492Q1_BLOPB  E=1e-22 s/c=0.47 id=35% cov=84%
---IIYEDDYLLALNKPTGVAAHGGSGLKFGVIEGLRALRPK-AQFLELVHRLDRETSGVLLVAKRRTALVYLHEQLRLQNMKKEYLALVHGrWNVNLQIVSVPLFKK------------------NTLLNSSRVVYIDSENGKFSTTHFQIKEyfdnvatflaIKPITGRTHQIRVHTQYASHPIVGDNRYGDYQSN-TRFKRFGFNRLFLHASILRFIHPKTKKKFHIHAPLGQSFHNCL--FFLRNLSIKN-----------------
>UniRef50_B8FLB4(83-313:321) Pseudouridine synthase n=2 Tax=Bacteria RepID=B8FLB4_DESAA   E=2e-22 s/c=0.47 id=38% cov=85%
-LAILYEDRDIVAVNKPPGMVVHPAPGHSSNTLVnaLLAHCKDLSGiggvQRPGIVHRLDKETSGVILAAKNDAAHAGLSEQLAQRRVEKFYLALAHGVIKEDTgVIDLPLARH---------PSDRKRMHVSTPAKGREALSLWTVKERFLDATY--VKVQIKTGRTHQIRVHLAALHHPVIGDTVYGGRKKrGRLPASVLGKapppERQMLHAHIVSFTHPVTGEKLTLTAPLPQDMAQLL-----------------------------
>UniRef50_Q1ILA4(82-320:333) Pseudouridine synthase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=Q1ILA4_ACIBL  E=4e-22 s/c=0.45 id=33% cov=80%
-LDVVYEDDDLAVINKPAGMMVHvgagATEEERNRGTLVNALLYrfralSEVGGDMRpgIVHRLDKETSGLIVVAKNDVAHRKLAEQFSSRRVHKKYVALVHGWPKKlKGTINLPIARDMSR-RTRMTTRGSGGRDALSHYEVKEKIESPYG-------KFALVEVKIETGRTHQIRVHMASLGHPVVGDTLYgapGELRVTKAlkgmPSKMASLERNFLHAAEIELQQPATGKAL-------------------------------------------
>UniRef50_B0TGQ0(112-342:369) Pseudouridine synthase n=44 Tax=Bacteria RepID=B0TGQ0_HELMI   E=4e-22 s/c=0.46 id=36% cov=83%
-LEIIFQDADIAVINKPAGLVVHPAEGHWSGTLVnaLLYHIKDLSGINgelrPGIVHRIDKDTSGLLVVAKNDRAHIHLTEQVKDHRVRREYLAVVHGVIGAET----------GRVEAPIGRDPKdrqrmaviaGGKSAITHFRVLA---------RYPEQGFSLLHCRLETGRTHQIRVHLAHIGHPVAGDPKYGP----RKAA--FGLTGQALHAWKLEFVHPRSGEPMRFQADPPEPFVQVLQAL---QMTPTNQR---------------
>UniRef50_B9Y836(80-300:307) Pseudouridine synthase n=3 Tax=Firmicutes RepID=B9Y836_9FIRM   E=2e-21 s/c=0.48 id=34% cov=83%
-LNVVYEDHDVIVINKPKGLVVHPGPGNPDHTLVngLLWHCHDLSGINGVlrpgIVHRIDKDTSGLIVACKNDNAHQSLAKQLAEKTAGRQYYALVHGVINHEyGTIDAPIGRD-EKDRQKMAVTEKNSRPAITHFKVVERFD-----------NYTLVSCRLETGRTHQIRVHMQYIGFPIVGDPKYS-LRKT------LPTQGQMLHAYQLSFTHPSTGERMTFEAPLPPEFEALLTQL--------------------------
>UniRef50_Q126H9(128-365:378) Pseudouridine synthase n=1 Tax=Polaromonas sp. JS666 RepID=Q126H9_POLSJ  E=3e-21 s/c=0.44 id=34% cov=88%
---VLFEDDFLLAIDKPAGVAVHGGSGVSFGVIEQLRMARPQ-ADFLELVHRLDRETSGILLIAKRRMALKLLQEQFRERETDKVYLALVSGnWPANHRVIDKALHKYLlpGGAGEGERRVKVVPNDHPDGMRSVTLVKVKSAFAALPAapgTPFTLLEVTIKTGRTHQIRVHLANEGHPIAGDDKYGDFELNKSLQKSVAggapLKRMFLHAWSLKFNHPKTRKTIHLETPLPDELQQFLS----------------------------
>UniRef50_Q1J0S8(97-338:341) Pseudouridine synthase n=7 Tax=Deinococci RepID=Q1J0S8_DEIGD   E=3e-21 s/c=0.43 id=40% cov=89%
-LDVLYEDEHLIAVNKPPGMVTHPAPGVTSGTLVNAllgrLTLPEQPGAvgpdgyRPGIVHRLDKDTSGVIVVAKTVEAHARLAAAFKDRSTHKTYLAIAAGmWKAQGPVSVNAPVGRHPTARQRMTVGGVGPREAQTLFTPLAT--HPDGHGRT----LALVRAQPHTGRTHQIRVHLAHLGSPILGDAVYG-----RASAV---MPRHALHAQFLTLPHPVTGETLHLHAPVPDDLLRAWVALG--GAVP----AELEAPS--------
>UniRef50_Q0AFD5(116-338:354) Pseudouridine synthase n=3 Tax=Nitrosomonas RepID=Q0AFD5_NITEC   E=5e-21 s/c=0.46 id=40% cov=81%
-FDTLYQDDYLLVINKPAGTAVHGG---SGISYGVIEQLRKQRPDWKFleLVHRLDRETSGVLLLARKRQTLLELHKQIREGTVRKHYLTLVRGkWKNSLQNVRLPLYKYLTaegerRVAIATGRNDHDKvQQAYTLFALQKNWEA-----------FSLLDAELKTGRTHQIRVHLAHLGFPIAGDDKYGDFGLNRQLQKDDGsglvLKRMFLHASVFVCTHPVTGELLRLEAPLPD-----------------------------------
>UniRef50_D2R7T3(115-339:355) Pseudouridine synthase, RluA family n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R7T3_9PLAN  E=6e-21 s/c=0.46 id=40% cov=82%
-LDILFEDEHLIAVNKPPGMVVHPArghWSGTLTSALAfhFQQLSTVGGQHrPGIVHRLDRDTSGVIIVAKTDPVHFSLAAQFADRTTAKEYFAITAGVPdRDRDVVSQPIG------IHPFHREKMAIRPGHSTSRDAET--MFHVLERF--AQHAAVECLPKTGRTHQIRVHLAHVRTPVLCDKLYGgraEITQGelvRDGSTEVVLNRQALHARKLSINHPKTGERLTIEAPL-------------------------------------
>UniRef50_Q6MEZ4(32-243:243) Pseudouridine synthase n=1 Tax=Candidatus Protochlamydia amoebophila UWE25 RepID=Q6MEZ4_PARUW  E=1e-20 s/c=0.48 id=34% cov=82%
-IQILYEDADLAIIYKPSGLLSVATAFEKGETTHALLKAHYK-PRKVFVVHRLDQDTSGVMVFAFNEKTCNGLKDLFEVHDISRSYTAIVEGQLLSpSGTWKSYLYEDSQYFVHETEDETYG-RLAITHYRTLKTLK-----------KYSLVELTLETGRKNQIRVHCQSAGHPVVGDKKY--------GAHTNPLKRLCLHAHLLAFKHPISRKIIRIESPIPEEFYRLIPK---------------------------
>UniRef50_C1F7V3(104-353:355) Pseudouridine synthase n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F7V3_ACIC5  E=1e-20 s/c=0.41 id=33% cov=86%
-LDIIYEDKDLIVVNKPAGMMVHAgsgatdSARNRGTLVNALLGRQEKLSKtggdlRPGIVHRLDKETSGLIIVARNDAAHQRLAEMFSQREIHKTYLALVHGHIAEDrGTINAAIARDVIRRTRMTTRRTEGARTAISHYRVQRRIE----------TRWGkftLVSVRIETGRTHQIRVHLSSIGHPVVGDTHYGapttivlpvanrARRKQLPAPEGLSLPRNFLHAAELKFPHPRSEKPLHLEAPLPAELVAFLEQL--------------------------
>UniRef50_A9NGF1(76-297:297) Pseudouridine synthase n=1 Tax=Acholeplasma laidlawii PG-8A RepID=A9NGF1_ACHLI  E=1e-20 s/c=0.46 id=33% cov=83%
-LNIVYEDDDIMVINKPKGLVVHPSETFSETTLVSgLLHHTDTLSTHNDdplrpgILHRIDKDTSGLILVAKTNEAHKILAQDLKSHDIKREYIALVEGVLdHNKGVIDAPIARH-PKIRTKMAVVATG-KPAITHFEVMRTFR-----------DHTLLHCKLETGRTHQIRVHLAYIKHPVTGDPLYGTKAKILKDGQ-------LLHAFRLEFVHPITKKVMMLEAPLPPEFESYLVTLG-------------------------
>UniRef50_Q87AR7(90-318:331) Ribosomal large subunit pseudouridine synthase D n=18 Tax=Gammaproteobacteria RepID=RLUD_XYLFT  E=2e-20 s/c=0.44 id=35% cov=85%
-LDILYEDEHVFVINKPAGLVVHPGAGNPDGTLVNALLHRDPALAAVPRAgvvHRLDKDTSGVMVVARTLQAQTALVEQLSSRQVHRQYLAVVVSALVSGGTVNAA-IERHPRDRLRMEVSDTGKE-AVTHYR-----------LRERFRAHTALECRLDTGRTHQIRVHMAHLRHPIVGDRLYgGSLKLPKGGTDALvamlrGFKRQALHAEVLEFLHPVRALPVRIVAPVPEDLCQLLAAL--------------------------
>UniRef50_C1ZMP6(6-230:246) Pseudouridine synthase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZMP6_PLALI  E=2e-20 s/c=0.45 id=36% cov=84%
---ILFEDNHCLVVEKPAGVLTMGDETG-DENMVQLAmddlKIRHQKPGNVYVglVHRLDRPVSGVLLLAKTSKAASRLSAQFREREPEKVYLAIVEGQLNPAAgeIVDWLIKDQERNHTRVTSPQTPGAKQAKLRYRQLETLVTPEGI-------RTLVEVQPMTGRSHQIRVQLAHAGASILGDLRYGS-------KTPLG-KMIALHARSLTFEHPVQKQPLTIYAPLPSDWKPFMNPLLW------------------------
>UniRef50_Q7MA82(70-306:308) Pseudouridine synthase n=1 Tax=Wolinella succinogenes RepID=Q7MA82_WOLSU  E=3e-20 s/c=0.42 id=37% cov=80%
-LEPLFIAPFFALFDKPADLLVHPK--GTFEHYSLMDEVRLRFGQEADLAHRIDKETSGIVLITRSKKEGAILKINFFNREVKKCYWALVRGKMEGERILDFPLKAQSKRLDLGVrMRVDEKGKSSLTQIKALDYEALSDTT---------LVEASPLTGRTHQIRLHLAHAGYPILGDPLYGTsdelsrayLEQAMDQEERrrcFGASRLMLHAQGLGF--PYKGSWYEIVS---------------------------------------
>UniRef50_C7NAV5(99-321:326) Pseudouridine synthase n=5 Tax=Fusobacteriaceae RepID=C7NAV5_LEPBD   E=4e-20 s/c=0.45 id=34% cov=83%
-IEIIYEDNDLAVINKKAGIVVHPANGHYSGTLVnaILYHIKDLSGINgeirPGIVHRLDKDTSGLLIIAKNDKAHLKLSQMFHDKTVKKIYLAILKGKLNQKS----------GRIVTQIGR-DKNDRKKMTVINDLNSGKTAITNYEVisQTEKFTLVKVHIETGRTHQIRVHMKHLGYPILGDSVYG-----RTDTE----KRQMLHAYKLEFQHPITEENLEFIAKLPEDFKKALKKCG-------------------------
>UniRef50_UPI00016C40E0(9-229:238) pseudouridine synthase n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C40E0  E=7e-20 s/c=0.45 id=36% cov=82%
-LAVLYEDHHLVVVNKPAPLLTQAPPgvpnLEERVRAYIKDKYAKPAGVYLGVPHRLDRPVSGVVCFARNTKAAQRVHSQFEHRSVRKVYWALVEG-----------VVEPDAGVWDDYIRKVENEARAARGHEGepgakLATLEFRVLERFAAHTR---IELHPLTGRMHQLRVQSAWRGHPVIGDSLYGSVRPFGPPAELPRDRVIALHARRLTFEHPFTKQELVIEAPVPAYW---------------------------------
>UniRef50_B8FT16(107-328:334) Pseudouridine synthase n=70 Tax=Bacteria RepID=B8FT16_DESHD   E=9e-20 s/c=0.45 id=36% cov=82%
-LEILYEDEDVLVVNKSQGMVVHPAPGAWTKTLVnaLLYHCRNLSGINGVlrpgIVHRIDKDTSGLLVVAKNDLAHQGLAEQIKAHSMARRYLAIVHGVVFEpSGTVEAPIGRDpADR--KKMAVVFQNAKEAVTHYEVLERFR-----------DFTLLEARLETGRTHQIRVHMAYLKHPVLGDPLYGP-RKNP-----FGLQGQMLHAQLLGFQHPRSGEYMEFSAPASGMFQKVLEE---------------------------
>UniRef50_Q0A8Q9(100-316:327) Pseudouridine synthase n=4 Tax=Ectothiorhodospiraceae RepID=Q0A8Q9_ALHEH  E=9e-20 s/c=0.46 id=38% cov=83%
---ILYEDDRLLVIDKPSGLAVHGGSGLAWGLIEVLRQARPS-APFLELVHRLDRATSGCLMVAKRRSALRELHEQLRTGAVHKRYLALLTGALGRGPI---PVEAPLER--------RSGPAGGVrvaSHGKLARTVFRAVARPGGMT----LAEADIATGRTHQIRVHAAHLGMPIAGDDRYGERAVNRR-LRGLGLKRLFLHAHRLELSAPGTGQPLSIEAPLPDELAAVVAQL--------------------------
>UniRef50_B1ZRU1(6-251:268) Pseudouridine synthase n=2 Tax=Opitutaceae RepID=B1ZRU1_OPITP   E=1e-19 s/c=0.40 id=37% cov=84%
---ILFEDDAMIAFDKPSGLLIAPDRWDK-QRENLMGLVHARFGHGVANVHRLDADTSGLLLCAKTKPALDFLSGQFQAKTVQKTYLSLVVVLPPEEAMkVVKPIRDDAGGLPDAFqvdlalgqderqpgrmrVFKGRGGKDCVTDFRVLERF-----------GRFALVSCHPQTGRTHQIRVHLAAAGAPILNDPFYGnpeiklllsDLKRRYKGrdEEKPLIDRLALHASELTFRHPATRELLTLQAPLPHEFEIALK----------------------------
>UniRef50_Q7NBQ4(84-296:312) Pseudouridine synthase n=1 Tax=Mycoplasma gallisepticum RepID=Q7NBQ4_MYCGA  E=2e-19 s/c=0.46 id=34% cov=80%
-LDIVYEDDDLIIVNKPTNMLSHPTTHNEPDTLLNCLMYHNK-KQKVYLAHRLDKDTTGLIVATKNFKALEKIQEQITK-RIMKRYYLAIVHYPFNElrAVIDAPIgyLKDHDL---KFGVENtKNPKNAITKIYVLDQ-----------NKKYALIKCELLTGRTHQIRVHMDFIKHNIINDPLYGVKGEQRTDYKQF------LHAYQLELTHPTTNVSLFFEVKPDEVFMKKL-----------------------------
>UniRef50_D0XS67(113-333:350) Pseudouridine synthase n=1 Tax=Brevundimonas subvibrioides ATCC 15264 RepID=D0XS67_9CAUL  E=3e-19 s/c=0.44 id=36% cov=81%
---VIYEDDLVIALNKPWGLAV-QGGTKTTRHVDRLLSAWGEGMERPRLVHRLDRDTSGVLLLGKGPEAAKRLAGAFARRQAKKTYWAIVMGLpkpadgqisvhLKKSGINDYEIMRPADP-------KDPGAEPAETAY----------AVISHAAQRASWMALRPFTGRTHQLRAHMKAIGHPILGDPKYGD----DASTQLSGPLKLQLHARRIELDHPAGGT-LVVEAPISAELRAGFEHFGF------------------------
>UniRef50_C1ZGS9(91-337:345) Pseudouridine synthase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZGS9_PLALI  E=3e-19 s/c=0.40 id=36% cov=90%
-LDILYDDEYLCVINKTANMIVHPGRGNyRGTLAGALQfhfdSLSDVAGQYrAGIVHRLDRDTSGVLVVAKDNTVHQHLSRQFEERSVEKEYHAIVWGEMQFDA--DY--VETYVRVSFR-NRERMMVCPPGDNARQAATFYE--VQQRFRGFTY--VKLQPQTGRTHQLRVHMHHLGHPIIADRlyegktcvKLSDiLPETPEEADETLIDRQALHARRLAFNHPVTKKRMVFEAPLPADFQKTLDTLKTHAIKPK------------------
>UniRef50_Q2NIN6(82-299:306) Pseudouridine synthase n=4 Tax=Candidatus Phytoplasma RepID=Q2NIN6_AYWBP  E=3e-19 s/c=0.45 id=32% cov=81%
-LDIIYEDPYLAVINKPANLVVHPSL--SFQKTTLVNGLLHQFNtlSHIDTqrpgiVHRLDKNTTGLLIVAKTNDVSDKLQIAFQQRKITKIYWALIEGFLEDKGIIKLPIgRNNHNRLKMQVMPDGKT---AVTHFKTLQ---------RF--SHFSLMECNLETGRTHQLRAHFSFLKHPIVGDLLY-------DSSHHITPLGQFLHSKILKFNHPITNQNLILEAPLPTNFEKLLKTF--------------------------
>UniRef50_B8FTI5(83-299:302) Pseudouridine synthase n=2 Tax=Desulfitobacterium hafniense RepID=B8FTI5_DESHD  E=3e-19 s/c=0.45 id=37% cov=81%
-LEILYEDDYFIAINKPAGQVVHptpRYPRGTIGNAVVGYWLAKGEARPFRPIHRIDRNTSGVVVIGKNQFAHQQMAWQHAHGRIHKCYRGIVEGQVMEdQGTIKAPIA----LAPDSFIQRQISPEgsPAVTLYKVLE---------RYQDA--SLLEFILETGRTHQIRVHCQHLGHPLLGDDLY--------GGNLARINRQALHSSIYEFNHPLTGELTTIQAPLPEDLQRLLREL--------------------------
>UniRef50_C6E472(78-299:302) Pseudouridine synthase n=4 Tax=Geobacter RepID=C6E472_GEOSM   E=4e-19 s/c=0.44 id=34% cov=83%
-LDILFEDSWIISLNKAPGLSVHRTE-DPDEVNLVdlaetLLQKRDGVGR-LRPVNRLDKGTSGAIILAKSAVAAGMFGKMVQEEGLGKLYLALVEGKLQKQGVIDAPLD----------GKESQTSYLRLFHGGGVS-----------------LLAVYPITGRMHQIRQHFKMIGHPILGDKRYG-------GRALTGFTGHALHSFKTTLVHPATGEEVNIPAPLPEQLMRLVSRYSGvseKALLDTLDQLPASGP---------
>UniRef50_A3EQJ0(95-329:339) Pseudouridine synthase n=1 Tax=Leptospirillum rubarum RepID=A3EQJ0_9BACT  E=5e-19 s/c=0.41 id=34% cov=83%
-LEILYEDEDLIVISKPPGLVVHpapghssgtlvngllfhfQSQGDEQKKGEPEEEEEAERPLRAGLVHRLDQDTSGVMVVGKTESVVLDLMNQFKDRSVSKKYLALVKGILPKKrGEINAPIGRSTHDRKKFTVRQDG--KPSVTRYRVLETYH----------ENYSLLEVTLLTGRTHQIRVHFRYLGFPLLGDAVYGS-----KGTENKNFPRQMLHAWKLSFQHPSSNSKMEFEAPLPPDFVSALERL--------------------------
>UniRef50_B7GAM3(73-295:325) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7GAM3_PHATR  E=7e-19 s/c=0.43 id=32% cov=82%
-LDIIFEDEHMIVINKAANMVVHPAAGNWDGTVVnalayYLANRSESISFRPGIVHRLDKGTTGVLVVAKTSQTLATLSNFFAARQVKKTYMAITVGNPGKHVVIDKPIgrhplhRQRMRVVPDPHQKNSTG-------RRALSYVDTLAFDG-----KLSLVQVRIETGRTHQIRVHLQDRHTPIYGDDIYGLADWNKKLSKTHRIVRPLLHAYKLEINHPVTGEPMVFKASLAD-----------------------------------
>UniRef50_C7MES4(103-314:318) Pseudouridine synthase, RluA family n=5 Tax=Actinomycetales RepID=C7MES4_BRAFD  E=1e-18 s/c=0.45 id=38% cov=81%
----LHEDEDLLIIDKPAGVAVHRGTDVPAGVIDALRQLRPEL-PDLELIHRLDRSTSGVLALAKSPSMLRYLHDLLrdREDEIERRYLALVAGhWPAETTILDAPLRREENRVV-----VDPDGQRAETH----------VAVAQRFGNRATLLEVRLLTGRKHQIRVHLQHAGHPIAGDDRYGDDAFNRRAAS-LGGTGLHLHAAELVIPRP-DGTTLAVTAPTPRRWEQLL-----------------------------
>UniRef50_C8W9Q3(10-240:246) Pseudouridine synthase n=2 Tax=Atopobium RepID=C8W9Q3_ATOPD   E=1e-18 s/c=0.42 id=32% cov=84%
-LEFLYQDDYLLAVNKPAGMIVHSDGTNEpsltdlvCEKLCALESSNKIDLSQVQALNRLDKETTGIVLFSLKKETQPQFDQLIASKELSKEYLAVVKGdFGLNKLLIDKAIGKDRHD-AQKMRISDTG-KPSQTEVRLIKVASS--AQGQIQS----LLLVNLLTGRKHQIRVHLSSLGFPLVGDVLYGGMSslQRKTKKKHRP-QPLMLHAYRIGFIHPVTGAKIVIKTDIPERF---------------------------------
>UniRef50_C1ZB48(82-317:325) Pseudouridine synthase, RluA family n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZB48_PLALI  E=2e-18 s/c=0.40 id=36% cov=85%
-LEILFEDDSLLVINKPAGLIAHPTGEIPDGTLInAVQHYLDKQSTHpglerPGIVHRLDRDTSGAMAICKEHLSHRLLSIQFQLGRISKSYLALVEGVLTDDQlVIDLP-IGRAPGCSSALMSCRADALEAQASKTSLRVVE------RFP--QHTLVEAKPRTGRMHQIRIHLATIGFPIVGDEfylKGGEIRplvwpESERVQVSLLINRQALHAACLSFAHPLTNEWQDFQAPLPDDLRQAI-----------------------------
>UniRef50_A9IQ66(81-330:334) Pseudouridine synthase n=5 Tax=Bacteria RepID=A9IQ66_BART1   E=2e-18 s/c=0.38 id=31% cov=87%
-LDILYEDDHVIVINKPAGLVVHPgngNWTGTLVNALIYHCGNSLSGiggvKRPGVVHRLDKNTSGVMVVAKNDLAHKSLSAQFSDHgrtcALDRRYHALIWGtphrnvWTIDASLGRSPHNRTKQAVVHK---QTPHARHAVTHFSLLEK----YGTHADSTSFASLLECRLETGRTHQIRVHMAHIGHPLIGDTVYGNAFKTKSNTLNPTLKnaidqfnRHALHAASLTFEHPSSGKVISFSAPLPQDMAQLIKHL--------------------------
>UniRef50_B6AN83(95-329:340) Pseudouridine synthase n=2 Tax=Leptospirillum RepID=B6AN83_9BACT   E=2e-18 s/c=0.40 id=34% cov=83%
-LEILYEDDDLIVISKPPGLVVHpapghasgtlvngllfhfQSQGDEQKKGEPEEEEEAERPLRAGLVHRLDQDTSGVMVVGKSETVVLDLMNQFKDRSVSKKYLALVKGILPKKrGEINAPIGRSTHD-RKKFAVRQDG-KPSLTRYRVLETYH----------ENYSLLEVTLLTGRTHQIRVHFRHLGFPLLGDAVYGS-----KGMENRNFPRQMLHAWKLAFQHPRSAAKMEFEAPLPPDFVSAMKRL--------------------------
>UniRef50_A4CLQ5(11-233:236) Pseudouridine synthase n=16 Tax=Bacteria RepID=A4CLQ5_9FLAO   E=2e-18 s/c=0.42 id=38% cov=82%
-LMVLYEDNHLIAVSKRAGDIVQG---DKTGDTPLPETVKDYIAHkyqkpgKVFlgVVHRLDRPTTGVIVFARTSKALSRMNRLFAEGGTRKTYWALVGTPPPETAGRLVHWLERNQKQNKSYARakEVPGSKQAILNYRLLGSLD-----------RYHLLEIDLETGRHHQIRAQLAAIGSPIKGDLKYGFPRSNPDGGIH-------LHARRLEFIHPVRQDPVSILAPLpDDPLWEACGKL--------------------------
>UniRef50_Q0BWH2(81-326:341) Pseudouridine synthase n=3 Tax=Alphaproteobacteria RepID=Q0BWH2_HYPNA  E=3e-18 s/c=0.38 id=36% cov=84%
-LEILFEDAHLVILNKAAGMAVHPAPGSQTGTLVnaLLHHCQGQLSgiggvERPGIVHRLDKLTSGVMVAAKTESAHTGLAALFERHDIDRVYRAVTRGAprplsgTIEAAIAR----SESDRKKMSVHRNPDSPAArhAVTHYKAVETFGYKDRATRLPAA--ALLECRLETGRTHQIRVHMAHSGAPLIGDPVYGrqagimawkapgsEARYDKALAAARAFSRQALHAAVLGFVHPITGETLRYEAPLPE-----------------------------------
>UniRef50_C4XSN0(93-310:554) Ribosomal large subunit pseudouridine synthase D/dephospho-CoA kinase n=1 Tax=Desulfovibrio magneticus RS-1 RepID=C4XSN0_DESMR  E=6e-18 s/c=0.43 id=34% cov=80%
-LKLLYLDGDVLVLNKPAGLTIHPASSQPDGTLVNrllhhFPDMRAMAGDRPGIVHRLDKDTSGLLLVAQTESARLALAADFAERRVAKTYLALVHGRPeRSDGVIELPVGRD-PKHPTKMAVVAKGGREAKSSWKLAWTA---------PDGTASLLEVAIATGRTHQIRVHMAAMGHPIVGDAVYGARQHSdwtrRGGAMARLAKRQMLHAWKLAFSHPGTGEELSF-----------------------------------------
>UniRef50_Q82WZ5(109-330:344) Ribosomal large subunit pseudouridine synthase D n=2 Tax=Nitrosomonas RepID=RLUD_NITEU  E=6e-18 s/c=0.42 id=34% cov=82%
-LKILFEDDHLIIIDKPAGLVVHPgngNWHGTLLNALLNHAPQLSQVPRAGIVHRLDKDTTGLLVVAKTIEAQFDLARQLQQRTVKRHYLALVLGKLEKDGVVDAPIGRH--PIHRTRMAVVQNGKPARTHYRVLEKF-----------TASTLLHCSLETGRTHQIRVHLLSIGHPLAGDPVYGRTSPDPSTADAvVRLPRQALHAWQLELTHPHSGQILLWESPLPDD----------------------------------
>UniRef50_A6CF60(83-311:317) Pseudouridine synthase n=1 Tax=Planctomyces maris DSM 8797 RepID=A6CF60_9PLAN  E=8e-18 s/c=0.41 id=34% cov=86%
-LEVLYEDAWLIIVNKPPGMIAHPAgnILSGTVANALQYYLDQQTGVRSLlrpgIVHRLDQFTSGILIVAKEHLGHRSLSIQFQQNRVSKSYLAIVRDQPKQD------LFENNDAIGEHPTQAGVCMTTHPEALRAKAAFTRFEVVERLPG--HSLIRAFPKTGRLHQIRVHLADLGFPIIADDFYGN--DARLLDDRELISRQALHAEQIEFSHPVTSLRMNISAGVPADFQLALQR---------------------------
>UniRef50_B2UL66(77-312:323) Pseudouridine synthase n=2 Tax=Verrucomicrobiaceae RepID=B2UL66_AKKM8  E=8e-18 s/c=0.39 id=33% cov=87%
-LDILYEDEDVVVINKESGMVVHPAAGNPDGTIVnaLLHHCGDLSGiggvERPGIVHRLDKDTSGCLVIAKNDGAHQSLTAQFAARSTEKRYLAVVQGIPSQSSgtVFTHIGRHPVNRLKMAVVNPGSG-KAAITDYDLLCA---------DPSTDSSLVLCTLHTGRTHQIRVHMLYLGHPLIGDPIYAKPARQKAKP-----GRLMLHAWRLGFDHPRTGKRMDFEAPVPPEYTPWLQLFpnGLYGAIPE------------------
>UniRef50_A6C0W7(93-333:342) Pseudouridine synthase n=1 Tax=Planctomyces maris DSM 8797 RepID=A6C0W7_9PLAN  E=8e-18 s/c=0.39 id=34% cov=83%
-IDIVYEDDWIAIINKPSDMIVHPGKGNYAGTLAgALQYHFDQLsdvaGQYrPGIVHRLDRNTSGIMVVAKDNQVHAKLSAQFEKRDVQKEYRAIVWGRMefdtdyIDTFMCVHPRAREKMIVCD----EGGNARNAFTYYEVIE---------RYQAFTY--VRLKPRTGRTHQLRVHMQHIGHSIVADRVYGghkSLKMKSLGIQAEAdaaelesdvlIERQALHAYCLEFFHPQSGKPMKFEAPLPEDMQNTLA----------------------------
>UniRef50_C8P3R0(83-304:308) Pseudouridine synthase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8P3R0_ERYRH  E=9e-18 s/c=0.42 id=32% cov=82%
-LDIVYEDDAILVVNKPKGLIVHPSPSTLNQPTLVhgllahTTQLSDLNGElRPGIVHRIDKDTTGLLVVAKTNEAHEILVEDLKQRLISREYVAIVhHQFKHQSATVDAPIGRD-PKNRQRMAVTDQNSKQAVTHF---------YLAERF--NDFSVLRCKLDTGRTHQIRVHAQYIKHPIVGD-------QTYSYKNTWETNGQCLHAQKLTLTHPVSKEVMTFEAELPQTMKDVIEE---------------------------
>UniRef50_B1XXM0(119-337:369) Pseudouridine synthase n=6 Tax=Burkholderiales RepID=B1XXM0_LEPCP   E=1e-17 s/c=0.42 id=34% cov=80%
-LAVVHEDAHLLVIDKPAGLVVHPAaghWSGTLLNGLLAHHAAAAHLPRAGIVHRLDKDTSGLMLVAKSLQAHTALVRAIAARDVKREYLALVHGAVMDGlQVIDAPLGRDpVSRVRMAIVASGK---PARTDVRRLAVAELPgdgvrqlPGATRAP-RQVSAVHCQLHTGRTHQIRVHLASRGHPLLADAMYG-------GAPAFGLQRQALHAARLHLLHPIDGRPLAF-----------------------------------------
>UniRef50_Q2LWV4(85-329:333) Pseudouridine synthase n=1 Tax=Syntrophus aciditrophicus SB RepID=Q2LWV4_SYNAS  E=1e-17 s/c=0.38 id=36% cov=88%
-LSILYEDHDLLVLDKPAGLVVHPAAGHVSGTLVnaLLFHCRDLAGiggvMRPGIVHRLDKDTSGLLVVAKTDAAHQGLALQFKKHQVGKTYQALVYGDPREKtGQIDLPVgrhpVER-----KKMSTKSRRGKEAATRWR--IAERFGVAT---------LLNVDIVTGRTHQIRVHLAAIGHPVVGDAVYGSSKRATTLTDPAVKGRLkemsrqALHAARLSFTHPVTHKILEFHAPL-PADMEDLCAFLRKHCCPDSQLV--------------
>UniRef50_A4J1I1(83-299:303) Pseudouridine synthase n=1 Tax=Desulfotomaculum reducens MI-1 RepID=A4J1I1_DESRM  E=1e-17 s/c=0.43 id=33% cov=82%
-LSIISEDEDIALVNKQPGMCVHPTLAYPSGTLangLVYHWLENNPAPTFHAVNRIDRNTSGLVLVAKNSYSAQKLFLQRKRKQLARSYVALVHGKIVQrNGYIDLPL-EKCEGKTTKRQISSTG-QQALTRFEVLQYI-----------TDCTLIRLMPETGRTHQIRVHLSHLGHPLVGDTLYGG-----SIAQ---IGRHCLHADKISFLHPRTGHPMSFQIPLAEDMLQVITEMG-------------------------
>UniRef50_A6DUC9(90-318:323) Pseudouridine synthase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DUC9_9BACT  E=1e-17 s/c=0.40 id=31% cov=83%
-LDIIYEDDDILVVNKPAGMVVHpgagnytgtlvNALLGRDLDTF---SAMDDGSSRPGIVHRLDKETSGVIIVAKSAKNLDKLSRSFARRDVEKYYVALCRGTIRvgRDTITSHIGRSRSNRQKMENTNDSNRGKEAISHYKVLA-----------DNNGATLVKLKIDTGRTHQIRVHMSGINHPVVGDKLYGVRRLD----EKESPDRHILHAWRTRIIHPGTQEIMTFTAPLHDDFKSVCDKFG-------------------------
>UniRef50_C1CWT3(77-313:321) Pseudouridine synthase n=1 Tax=Deinococcus deserti VCD115 RepID=C1CWT3_DEIDV  E=1e-17 s/c=0.39 id=36% cov=85%
-LDVIYEDDYLIAVNKPPGMVTHPAPGVLSGTLVNALLGRmplpeqpdydSEAGYRPGIVHRLDKDTSGVIVVAKTVGAHARLAAAFKDRETRKTYLAIAAGqWradgpaRVEAPIGRHPVQRQRMTVGGANPRE------AQTLFTPLAA--HPDGHGRT----LALVRAQPRTGRTHQIRVHLAHLGSPILGDAVYGRSSET--------MLRHALHAHFLSVPHPGTGRLLHLHAPAPDDMLNAWIALG--GAMPSD-----------------
>UniRef50_C4XFS9(84-313:315) Pseudouridine synthase n=2 Tax=Mycoplasma RepID=C4XFS9_MYCFE   E=1e-17 s/c=0.40 id=31% cov=86%
-LDIKYEDDDLVIINKPSNLVVHPSPGHYNDTLVngLLYHFKNNLSNENgllrpGIVHRIDKDTSGLLIIAKNNKMHNSLTDMLKRHEIERSYLAIVRG-LIENPLTKINLPIARNTVDRKMMSVHKEGKEAITFVHLLKHFYL----DKEPMS---LVRCELKTGRTHQIRVHLSYIKHPVYGDPTYG------KSVDEFN-QR--LHAYKLKFIHPLTKKEICVYAPVPKEF--DVADYDFNELLKNN-----------------
>UniRef50_A7HM17(79-304:314) Pseudouridine synthase n=2 Tax=Thermotogaceae RepID=A7HM17_FERNB   E=1e-17 s/c=0.41 id=33% cov=83%
-LDIIYEDRDILVINKQPGIITHPIPSHTSGTIVngVLYHCKDLQGIGGVlrpgIVHRLDKDTSGVMVIAKNDLAHQSLTKQFKDRLTEKLYICLVKGVPkrkegdIEINIARNPVL----RVKMTVTNSEYG-KPALTHYKVV----------REFGDIAALVFAYPKTGRTHQIRVHMKYIGHPLMGDEVYGRAKED----EIFGIKRQMLHALSLSFYHPRTGEKVKFIAKIPQDFKEAIQKL--------------------------
>UniRef50_Q6AJM1(95-326:327) Pseudouridine synthase n=1 Tax=Desulfotalea psychrophila RepID=Q6AJM1_DESPS  E=2e-17 s/c=0.40 id=33% cov=87%
-FESIYEDDSLLVLSKPPGIVVHPGNGNTEGTLVhgLLYHCREigGVGDAIRpgIVHRLDKDTSGAMVVAKDERSLRTLVDSFKERQVYKVYHALVCGIPKKyEGRIVAPIGRH-SVHRQKMAISERTGKFAATNWQVVEVFE----TKDGP---YSLLRVHIETGRTHQIRVHMSSIGCPIAGDQVYGSKRQNPAFA------RQMLHASRLRLPHPVTGRTMSFTAPLWQDFQEVLEDMDWSGAL--------------------
>UniRef50_B9XDK1(15-248:283) Pseudouridine synthase n=1 Tax=bacterium Ellin514 RepID=B9XDK1_9BACT  E=2e-17 s/c=0.39 id=36% cov=81%
LIPILYEDRSVLAVDKPAGWMLAPDSWDKTGRNLQL-ALQSSLNAGDFWAhsrnikflryvHRLDAETTGVLLLCKSLGALRAYGELFETRSVEKFYLAVVQGipkqseWTCKLPLIADPVVKgkmQVVTPGKPLPKSDpRGPQAelkdAETHFRVIQTLQ-----------DKALVEAQPMTGRTHQIRVHLAASGHPIVGDPLYG----NAPAAASKGAQIIALRAIKLIYWDPFQKRQIRIAAPTDE-----------------------------------
>UniRef50_A4J9H9(102-315:320) Pseudouridine synthase n=2 Tax=Clostridiales RepID=A4J9H9_DESRM   E=2e-17 s/c=0.43 id=32% cov=81%
-IEVLYEDDFLLVLNKPAHQLVHptgQTTRGTMANYLAYYLKQRNVVSAIRPVHRLDRETSGCVIFAKDSRSQFILEQQLKERTLKRTYWALVKGIVHPPSgTIDAPIGPH-PSLANRRAINEHGEQ-SITHYQTLRS---------FPEI--SLLKLNLDTGRTHQIRLHLAHLGYPIIGDRMY--------GVRSPWINRQALHAYDVSFRHLKENHEIAVHAPLPTDFAQAIN----------------------------
>UniRef50_C8PVB8(143-375:380) Pseudouridine synthase n=2 Tax=Moraxellaceae RepID=C8PVB8_9GAMM   E=2e-17 s/c=0.39 id=33% cov=84%
-LDILYEDEAVLVINKPVGLVVHPGAGNGSGTLVnalLFHYPDSRTLPRAGLVHRIDKETSGLMVIAKDSQSQLHLINQLKDKSVYRLYQAIVLASAAELArhrTIDAPIGRHPTQ-RTKMAVVSSG-KPAVTHLEKITAISDAVS----------LVSVRLETGRTHQIRVHLSNLGFPLLGDPLYGAARKNAillktldDDQKHIvqQFQRQALHAYELGFIHPKTGEPIKVQARLPEDMQQLL-----------------------------
>UniRef50_A0L7F8(15-232:255) Pseudouridine synthase n=6 Tax=Proteobacteria RepID=A0L7F8_MAGSM   E=4e-17 s/c=0.42 id=34% cov=83%
----LYRDGLLLIINKPAGIPVHAGPGGGANLEALFGGLRFGLPKAPALAHRLDRDTSGCLVLGRHAKALSKLGKLFSQGKVQKTYWAVVQGGPPQaQGSMDFPLY--------KISTAQQGWRMVVDPEQGKSSLTLYRVLGRSATHSW--LELTPKTGRTHQIRVHCAHVGLPIEGDLQYG-------AAPSEPQLTLHLHARQIILPISASKAPINVSAPPPRAMRGLLEQCGYR-----------------------
>UniRef50_Q38Y05(83-296:296) Pseudouridine synthase, 23S-rRNA-specific n=1 Tax=Lactobacillus sakei subsp. sakei 23K RepID=Q38Y05_LACSS  E=5e-17 s/c=0.42 id=35% cov=80%
-FSVLFESDDLLIVNKPAGIKTHPNR--PGENGTLMNQVAfylAQQGKKAYMVHRIDEATSGTLLIGKTPIVIGILNRQLSQKKMARQYIAIVddpKHELAEHATINSPIGVDPENDRQRCVDYING-LSAITHYRVLS---------RKGATAVLAVDLE--TGRTHQIRVHLASIGHPILGDPLYNPTDTT---------PRLLLHGQTLRYTEPYTDQPRTVTAPVPDAFEPYLS----------------------------
>UniRef50_B9JRD0(90-338:342) Pseudouridine synthase n=1 Tax=Agrobacterium vitis S4 RepID=B9JRD0_AGRVS  E=6e-17 s/c=0.36 id=35% cov=83%
-LTVLYEDKDLIVLSKPAGLVVHPgagNWTGTLVNALIHHCGDSLSGiggvKRPGIVHRLDKETSGVMVVAKNDIAHRHLADQFADHgrsgPLERAYQALVwgrpRGL---RGTIDAALGRAGDRTKRTVKREDtDDAREAITHYQVMERYgEKPDA-----TCLASLVECRLETGRTHQIRVHMAHIGHPLIGDPEYGaafktkaNLLPDAAKAIVTNFHRQALHAYLLAFEHPTTGDVMHFAAPIPD-----------------------------------
>UniRef50_A9GP63(19-277:666) Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GP63_SORC5  E=7e-17 s/c=0.35 id=40% cov=82%
---ILAEDGDLIVVDKPAGLSTHAPEAERiDDMVTRLRAFlrgRGDAEAYLGIHQRLDRDTSGVLLFTRRREANAAVARQFEGRTVQKTYVAAVSGFgdrpprgTLRHRLVPAPggamraLAESGGAREDRAAkREDR----AAGREDRAAKREDRAASGVLAITRYrllerrgdrALLELRPETGRTHQLRVQLAAIGLPIAGDPLYG-------GPE---APRLLLHAAELRLDHPATGAAATFRSRLPavfEAWLAA------------------------------
>UniRef50_D0KVM5(81-307:340) Pseudouridine synthase n=11 Tax=Proteobacteria RepID=D0KVM5_HALNC   E=8e-17 s/c=0.40 id=34% cov=83%
-LDIIYEDDAIIVLNKSPDIVVHPAAGNPDGTLVNALLFHDPSLVSVPRAgvvHRLDKQTSGVMVVAKTLAAHKILVENLAARKIRREYDTVVMGHVVAGGTVDAPIGRH-PRDRQRQAVTATGKR-AVTHYRVLQ---------HYGEQTWLRVQLE--TGRTHQIRVHMAHIRHPVIGDPVYGGrprIPPRASTAlidvlRHF--ERQALHARYLTLAHPVTGTQMRFEAPMPDDMRELIA----------------------------
>UniRef50_C6XFD0(90-340:340) Pseudouridine synthase n=1 Tax=Candidatus Liberibacter asiaticus str. psy62 RepID=C6XFD0_LIBAP  E=1e-16 s/c=0.36 id=28% cov=88%
-LDILYEDDDIIVINKPAGLVVHPApgnWTGTLVNALLYHCHNNLSSINGVkrpgIVHRLDKDTTGVMVVAKNDLAHQKLSEQFVDHgkstRLKRAYYAMVWGIpLPDSGIINAPLGRCKSNRLRRAVKgiDDKTADSAITHYQ---TIEIYNKNSNFAVS---LLKCHLETGRTHQIRVHMAHKGNPLIGDPLYGkgfktkaNIVNNNAKSAILSLARQALHAHSLSFSHPRNNQDMDFQVPIPEDMLTVIRKLN-------------------------
>UniRef50_A5WFS2(181-402:420) Pseudouridine synthase n=3 Tax=Psychrobacter RepID=A5WFS2_PSYWF   E=1e-16 s/c=0.40 id=33% cov=81%
-LDIIYEDDSVIVINKPVGMVVHPGAGNWSGTLVNGLLYHYPNQAHLPRAglvHRIDKNTSGLLVIGKTKAAQLELQEQLKDKSVYRHYQCVVAGdapSLARQRTIDAPIGRHRTQRT-KMTVTSTG-KTAITHIMKITPL----------SDTYSLLDVRLETGRTHQIRVHLSHIGHPIIGDDIYGNRQQLRAGltpEQRQAIQsfpRQALHAYKLGFIHPETGESIELTAPL-------------------------------------
>UniRef50_B2A2J2(91-319:328) Pseudouridine synthase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF RepID=B2A2J2_NATTJ  E=1e-16 s/c=0.39 id=34% cov=82%
-LDIVYEDEYLLVVNKPRNMVVHPGAGNyRDTMVNALlyhcQNLSDGTSyERPGIVHRLDKDTSGLLVVAKQNETHDILSEEIKNRRVARTYLALVIGdFSKKKATIDLPI-----------GRDPRNrKKMAVVHggKRAITKVEMLRSFQNPEKISYLKCSLE--TGRTHQIRVHLSHLGYPLLGDpvyrgktGKNVDIDKNLTGQA--------LHSFSLAFTHPVFKKTMVFRAPLPSDMMNLISKL--------------------------
>UniRef50_C6VWD2(24-254:255) Pseudouridine synthase n=2 Tax=Flexibacteraceae RepID=C6VWD2_DYAFD   E=1e-16 s/c=0.39 id=37% cov=81%
---IIFEDEDFLVVNKPP----HLATLDErtaDRGGSVLRLAK-EYNPELQAAHRLDKETSGALAFAKNPAAYRHLAMQFEHREVTKRYHAVVNGIHDLEGISVYlPILPLKNGTAVKIDRADGKEAETIFNtlqvYRG-----------------YTLVECIPITGRMHQIRIHLSCLKAPIVNDPQYGgepiflsnlkrKFNLKKDTEEQPLIQRVALHARSLSFAL-MNGEDIRVEAPYPkdfEVLVKQLNKFG-------------------------
>UniRef50_C9LM35(80-300:308) Pseudouridine synthase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LM35_9FIRM  E=2e-16 s/c=0.40 id=31% cov=82%
-LDILYEDNDMIVINKRRGVVVHPGAGNTEGTLV--NALLFHCGEQLRSvgdperpgiVHRLDKDTSGVMVAAKSERAYGILQKEIASHKAQRCYIALVHGQMEgDTGVIRLPLGRSTKDRMKWDVLHETG-RPAVTHFHVIEYL-----------PHYSWIECKLETGRTHQIRVHMAHIRHAVVNDPLYGWKK------DHFPIKGQALHSHTLELCHPITGEVMHFEAPVPEDMINCLN----------------------------
>UniRef50_B5JUW4(97-318:321) Pseudouridine synthase n=1 Tax=gamma proteobacterium HTCC5015 RepID=B5JUW4_9GAMM  E=2e-16 s/c=0.40 id=35% cov=83%
---ILFEDERLLVINKPSGMAAHAgSGVPFGIAEAVHQHHCD--GKRTELVHRLDRETSGCLLLAKGRSVLNVLQDSFRQRETHKQYLALLVGDLKGSRRVDLAL-QKTKLSGEAMVVVDEAGKSALSDFEPLA---------HYPwnDRTLTLARVTIHTGRTHQIRVHARALGLPLLGDDKYGDERLNRD-AKRQGLKRLFLHAE--SIRFPLEGQTLYFEAPLDADLEQFINAL--------------------------
>UniRef50_A7NB61(88-310:332) Pseudouridine synthase n=18 Tax=Francisella RepID=A7NB61_FRATF   E=3e-16 s/c=0.40 id=27% cov=84%
-LKIIFEDDDIIVIDKPVNMIVHPGAGNPTGTVsnALLHRYKDQDKlPRAGIVHRLDKDTSGLMVAAKSSIAYHNLVQQLAERKVSRKYLAIVEGEIYQQGTINQPI-----------GRDPTNRTKMAINYRGKEAITYYTPIEVYDG--FTLIECQLETGRTHQIRVHMKSIKHPLVGDQTYN---KSSTKLEKLAItipTRQALHAYKLSFIHPTTAKMVKFKSKLPEDMLNLKAQL--------------------------
>UniRef50_A9BMW0(125-347:356) Pseudouridine synthase n=10 Tax=Comamonadaceae RepID=A9BMW0_DELAS   E=4e-16 s/c=0.39 id=36% cov=80%
-LDVVYEDEHLLVVNKPAGLVVHPAPGNWTGTLLNGLLGRDPKAREVPRAgivHRLDKDTSGLMVVARSRAAMDALVAMIAARDVSRQYLALAhKAWgPRKHREVDAPIgrdprnrlrmaVVDLAQHAGKTARTD-----------------IDLLAG---NEEVSLVRCTLHTGRTHQIRVHMASLGHPLVADAVYG-------GKEAGGMARQALHAFRLAFTHPMTGQALVLRAPLPPDMAQALENWG-------------------------
>UniRef50_B5ZBC1(79-296:299) RluA n=15 Tax=Ureaplasma RepID=B5ZBC1_UREU1   E=5e-16 s/c=0.40 id=30% cov=83%
-LEIVFEDQDLLVINKPSGMLVHPTSF--QEQNTLANALKHYLKTDDFyITHRLDKNTSGLIVICKNQKALCCLQQQFMQKTVKKSYYAIVHNRF-DMHHLHFMINEPIGHSYQDKLRMKTGDAKNVKEAISIVKV-----IEQYQNT--ALVEVSIITGRTHQIRVHMRHINHPIYNDPLYG-ISKHTTPYEQY------LHSFYISFIHPSTNEIVEFKTLMPNEFINLIKE---------------------------
>UniRef50_Q9JVB6(105-330:374) Ribosomal large subunit pseudouridine synthase D n=39 Tax=Proteobacteria RepID=RLUD_NEIMA  E=5e-16 s/c=0.38 id=31% cov=84%
-LDIVYEDDTVIVVNKPAGLVVHPAagnWTGTLLNGLLAHCPELSQIPRAGIVHRLDKETSGLMVVAKTLPAQNSLVWQLQERTVKRIYRAVANGIVPFDGKIETQIGRDPHNRL-KMAVVKFGGKPAVTHVKVLE---------RYLAHSY--IECSLETGRTHQIRVHMREANHPLAGDPVYGNPRHPcgdtvKEAVKSLG-ARQALHAYRLSFTHPESGETVSFEAPIPDDIYHLLS----------------------------
>UniRef50_C5WJF2(127-341:341) Pseudouridine synthase n=104 Tax=Lactobacillales RepID=C5WJF2_STRDG   E=5e-16 s/c=0.40 id=32% cov=83%
-VDCLYEDDHLIIVNKPEGMKTHG---NEPTELALLNHVSAYTGRTCYVVHRLDMETSGVIVFAKTPFILPILNRLLEKREISRDYWALVHGTLSSKEVSYREPIGRHRHDRRKRVVDVKQGQKAVTDVKLLKSFKQNVS----------LINCRLQTGRTHQIRVHLSHHGHALLGDPLY-----SKGKAE---CPRLMLHAHQLRLRHPLTQEMICVQAK-STTFETVLQQVKAKG----------------------
>UniRef50_B3DV48(91-316:325) Pseudouridine synthase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DV48_METI4  E=6e-16 s/c=0.38 id=33% cov=83%
-LEILYEDEEILIVNKQRGMVVHPScghWSGTLVNSLLFHYGESLPGSSLLrpgIVHRLDKDTSGVMVIAKTERSLKSLLLQFSQRTVQKVYLCLCKNRF---PYLRYSFEANIHRHASDRKKM------AVHRLKG-KTAETRF-TLLFASSQASFLKCEPVSGRTHQIRVHLSHLGFPIIGDPLYGK------GVRKYPFP-LLLHAYALKIEHPRSGKKIEFMAPLPQDFKEALDFF--------------------------
>UniRef50_B8LC17(80-304:341) Putative uncharacterized protein (Fragment) n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LC17_THAPS  E=1e-15 s/c=0.38 id=36% cov=85%
-VPVVYEDDHMAIVNKPSGVVLYRAEGGRGGGARDEDTPQNVPLKRPQPVHRLDRPTSGLVVVAKTKLAAVHLSQQFEFRKAEKTYVAIVNGIPRQSGVRAEPM--QWNTI--DYDLEEKT---AVTRWRVLRKVKSLHGNDGTLT----LVEMKPKTGRYHQLRRHCAWVCNsPLVGDTTYdggseGALRLRKRG--------LFLCSSEIALEHPHYNTP----AGQKE-WVELKRNKQQLSFLQENE----------------
>UniRef50_P75485(80-299:309) Uncharacterized RNA pseudouridine synthase MG209 homolog n=2 Tax=Mycoplasma RepID=Y292_MYCPN  E=1e-15 s/c=0.39 id=32% cov=83%
-LDILYEDEQIMVVNKPNGLISHPTSFNESESLLGAALFHCN-HQPVFLVHRLDRDTSGVIMLA-KNQSSLLHLQKQLQQRVMKRYYLALVHFPLDslSGTISAPL-ERVgnNKVMWKVGNSSNKAKNAFTKFTVLNQNE-----------KAALIKCELLTGRTHQIRVHLQFIKHPVYNDPLYG-LKSEQ--ATEYG---QYLHAQQISFIHPTLNKEMGFEAQLDKTFSDKLDNLNLK-----------------------
>UniRef50_B1ZYX0(80-305:311) Pseudouridine synthase n=4 Tax=Verrucomicrobia RepID=B1ZYX0_OPITP   E=2e-15 s/c=0.38 id=34% cov=82%
-LTVLFEDKHMLAVNKAAGMVVH-PGVATSEDTLVHALLAHCAGslsgiggvERPGIVHRLDKETTGVIVVAKTDAAHRALADQFATRTLKKEYVALVAGvprllsGSIDRAIARHPVHRHRMTVGE-------GGRPARTDW------ELVEAFGDI----GALVRCRIFTGRTHQIRVHLKSLGHPILGDALYGWKPEPRLATQP---ARVMLHAEHLVLTHPISGKELDLRAPLPKDFVAMIKEL--------------------------
>UniRef50_A1URK8(80-329:336) Pseudouridine synthase n=2 Tax=Bartonella RepID=A1URK8_BARBK   E=2e-15 s/c=0.34 id=32% cov=85%
-LHILFEDDHIIVVNKPAGLVVhpgHGNWTGTLVNALIYHCGDSLSGiggvRRPGIVHRLDKNTSGVIVVAKNDLAHKGLSAQFSDHGrtgvLDRRYHALIWGSPNRNIGV---ITASLGR-----ARYDRTKQAvihshniyarhAVTHFSVIEKYQ--TCADKIPFA--SLLECRLETGRTHQIRVHMAHIGHPLVGDTVYGNAFKTKSNrfdstiKEAIDLfNRQALHAASLTFEHPAKGNIMSFSAPLPQDMAELINHF--------------------------
>UniRef50_D2R7R1(6-229:245) Pseudouridine synthase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R7R1_9PLAN  E=2e-15 s/c=0.38 id=34% cov=80%
-FEILLEDSAVLVVNKPAGILTQAPLgidsLEWQIKRYLQSTEKSEV-PYLGVPHRLDRPVSGCICFAKNQKAARKISQQFEARLVQKTYWALVSGIVHPTRSTWVDHLKKLDGEPRTIVVDERDPEgkNAILHYELLETRE-----GR------SLLAITLETGRTHQIRVQCGSRGFPLLGDRLYG-------SAEPFGPlaaderdQLIALHARTLAFRHPVTKEDLIFTAQVPAIW---------------------------------
>UniRef50_C7H7W3(80-308:314) Ribosomal large subunit pseudouridine synthase D n=2 Tax=Faecalibacterium prausnitzii RepID=C7H7W3_9FIRM  E=2e-15 s/c=0.37 id=34% cov=85%
-LDIIYEDAHLLVVNKPKGMVVHPAPGNPDGTLVNallwhCKGSLSGIGGEIrpGIVHRVDKDTSGLLVVAKDDATHIGLSQQMAVHSVERAYNTIVYGGFAQ----DEGFVES-NLGRSKTDRKKMAVYPASEPHTKYAY------TGYKVLERLGeftMLECRLKTGRTHQIRVHMASIHHPVAGDPVYGPHNCITS------LHGQCLHAKTLGFIHPITGEHLRFDSELPDYFTRFLTTLRQR-----------------------
>UniRef50_D2R760(379-594:603) Pseudouridine synthase, RluA family n=2 Tax=Planctomycetaceae RepID=D2R760_9PLAN  E=3e-15 s/c=0.39 id=33% cov=82%
-IRVVYEDEAIAVVHKPAPLPLHASGrFHRNTLEWILREIYDP--QKPRPVHRLDANTSGLVLFARTRHFAKLLQQQFTQGKVEKFYLALVSGHPVEDRfVSTAPISAEAGVFGSRSVDEEAG-LPAETRFEVLARTT--TADGK----PVALVRCQPITGRTNQIRVHLWQLGHPIMGEQSYlADQKHGTTQTHTVDDPPLCLLAHQLSFQHPVSRERMTFTSQL-------------------------------------
>UniRef50_Q1D9A6(82-314:316) Pseudouridine synthase n=2 Tax=Cystobacterineae RepID=Q1D9A6_MYXXD   E=4e-15 s/c=0.36 id=36% cov=85%
-LTVLHEDDSLVFVDKPAGRPSH--PLQSGETGTVANALVARYPECALAsldaregglCHRLDVETSGVVVAARTRDAWNAVREAFGSRAVDKRYLALVTGPLTDEGDIDLPLrhhPRHPDRVEPApYGAEDA--RDAVSKFTVLSR-----------SGEFSVVEVKILTGVLHQVRAHLAGIGAPIVGDSLYG-------GREAPELGRFFLHARSLGLTHPQTRRNMTVHSPLPPELRAELER---RGLpLPRGEQ---------------
>UniRef50_Q13E92(178-411:426) Pseudouridine synthase n=28 Tax=Alphaproteobacteria RepID=Q13E92_RHOPS  E=4e-15 s/c=0.36 id=33% cov=82%
-LEIVHEDDDIIVIDKPRGLVVHPAA--GHETGTLVNALIAHCGESLSgiggvrrpgIVHRLDKDTTGLMVAAKNDRAHQSLSAQFADHgrtgELRRGYYAFVWGAPNRiRGTIDAP-IDRHPHAREKMAVRDGG-REAITHWEVLETF-----TGRSGGEIVSLIACQLETGRTHQIRVHLAHIGHPLLGDDVYGPHFKTKASqlrpdarAALTDLGRQALHAYLLVLEHPSTGEVVAWESGL-------------------------------------
>UniRef50_B8GZR6(103-322:342) Pseudouridine synthase n=2 Tax=Caulobacter vibrioides RepID=B8GZR6_CAUCN  E=4e-15 s/c=0.38 id=34% cov=80%
-LSILYEDAHLIVVDKAAGMAVHPAPGTYNGTLV--NALLHHCGASLSgvggvarpgIVHRLDKDTSGVMVAAKSDAAHRGLSTLFATHDIDRLYVALTRGAPNPPTGTIQTQIGRSPGDRKKMAVLRAGGREAITHYR----VEAAFGPADRPLAARVACRLE--TGRTHQIRVHMASKGSPCLGDPVYGAAQPAaavRERIEAAGLRRQALHAAVLGFVHPITGETL-------------------------------------------
>UniRef50_D0RPR1(81-311:325) Pseudouridine synthase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RPR1_9RICK  E=4e-15 s/c=0.36 id=31% cov=82%
-LNIIFEDQDIIIIDKPIGMVVHPGAGNYEDTMVngLLYHCKNNLSgmngeDRPGIVHRIDKDTSGLLVVAKNDQAHAFIAKQFEEHSIKRSYLVFVYGILR-------PLHGKIETLIgrNKTNRQKMSAdvirgKDAITNYETLEVFK----GNKIPDI--SLVKCILETGRTHQIRVHMSHKGNPILGDQTYGkKIKKIRGIDQEFeeilkSLKRQALHAHTLGFIHPTTNEEVFFASELPD-----------------------------------
>UniRef50_Q0ANT2(91-315:330) Pseudouridine synthase n=2 Tax=Hyphomonadaceae RepID=Q0ANT2_MARMM   E=4e-15 s/c=0.37 id=35% cov=82%
---VIYQDDELIAFNKPAGLAVQGG----SKTTRHLDGMLDAFGEGLdrpRLVHRLDKDTSGILIVGKGPKATARLAKAFQSHKTRKTYWAIaigvpkpkmgeIKGFMRKAAASG---VDSERETMVAAGHGDEGAQHALTRY---------VVIGEA-GQKASWVALRPVTGRTHQLRVHLAAMGTAILGDKKY---TCHRPAPEDLG-RRLCLHARRLEIPRP-GGKPLVLTADLPPALKKIYDTLGF------------------------
>UniRef50_Q7PQ70(52-282:300) AGAP004401-PA n=4 Tax=Culicidae RepID=Q7PQ70_ANOGA   E=5e-15 s/c=0.36 id=31% cov=85%
-VDVLYTSGNFLVINKKHDLLINSNDTKKKTVQTIMrkqfpEYVQDNLTHDFYFAHRLDFATSGILCIPLNKNACKEVCQVFEEQRARKYYLALLRGHTdFDEEVIDIAIGEDV-RFKDTSKKmctilEDELCQNPRRSITKVLVLDRGYYNGK-PVTK---VLLRPITGRRHQLRLHCSQIGHVIVGDYTYS-LKIDTSPP------RMFLHAFRLVL--PNTIENLDIQT--DDPFTEKALKYKWK-----------------------
>UniRef50_A0LPH5(87-321:344) Pseudouridine synthase n=1 Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LPH5_SYNFM  E=6e-15 s/c=0.36 id=32% cov=83%
-LEILFEDDDVLVLNKAPGVIVHPGAGHEEGTLVhgllahCSRLASRGAPRRPGIVHRLDRGTSGALMVAKSERAYLELIRQFKHHEVGKEYLALVYGTMagasgeIRTGMGRHPVDRKRMAVLEKGGRE------AVSQWK------VAVAWGEVSLLRVVI-----KTGRTHQIRVHLSHMQHPVVGDETYGGGKRKARAVKSDVLRELlmevdrqMLHAVGLAFRHPVSGADLSFTAPLPPDFAGLLER---------------------------
>UniRef50_C4FWV7(81-308:309) Pseudouridine synthase n=2 Tax=Firmicutes RepID=C4FWV7_9FIRM   E=7e-15 s/c=0.36 id=31% cov=85%
-LDIIYEDEDILVINKPAGLVVHPSKGHLKGTLVngLLHYLNGNLstGSDFYrpgIVHRIDKDTSGLLVVAKHNAAHQALADQLLNHDMRRSYIALVHGQVKApQGTIEAPLQRDpANRLRWTVAKEGK---YALTRFQVMENFENAT-----------LLDLELETGRTHQIRVHLEFIGHPLVGDPVYRKGLDHIKGSLVHDMTGQLLHAYALKLQHPRSGEWLEFKAPLPRRFEEALDQL--------------------------
>UniRef50_A5GW76(88-309:316) Pseudouridine synthase n=1 Tax=Synechococcus sp. RCC307 RepID=A5GW76_SYNR3  E=8e-15 s/c=0.37 id=32% cov=83%
-LDVLFEDEHLIVINKPAGLTVHPAPGNKDGTLVngLLHHCPDLPGisgkLRPGIVHRLDKDTTGCIVIAKSQQALVKLQVQIQKRVASREYLAVVHGVPAGESgtIVGAIGRHPVDRKKYAVVSSDNG-RYACTHW------SLQERLGDYSLLRFKL-----DTGRTHQIRVHCAHRNHPVVGDPTYSRCRK-----LPIELPGQALHAVQLGLDHPITGERMVFEAPLPEVLEKLLA----------------------------
>UniRef50_C4PNG9(89-318:335) Ribosomal large subunit pseudouridine synthase D n=11 Tax=Chlamydiaceae RepID=C4PNG9_CHLTZ  E=8e-15 s/c=0.36 id=33% cov=80%
-LDKVYEDDMILVINKPRDMVVHPAPGHTQGTVVhaLLHEIGERLKQEFpeepwrpGIVHRLDKDTSGLLITVKTRRAKALYSELFATKQVKKLYVAICINApsqeLIHTRIARHPLKRKEMTVLSTHA---EGGKEAITHCHVLAT-----------NGRLSVVALYPETGRTHQLRVHMKHLGTPILGDPVYGIPSINF----RYGLDKQQLHAYSLVFAHPESAERVKLVTKLPDD----------------------------------
>UniRef50_A9IIW7(107-322:324) Pseudouridine synthase n=5 Tax=Bordetella RepID=A9IIW7_BORPD   E=8e-15 s/c=0.39 id=30% cov=82%
--------DWIV-VDKPAGLVTHPgagNWSGTLLNGLLHRYPELARVARAGIVHRLDKDTSGLMVVARNELAQTHLVRQLQARSMGREYIALAHGWLPVAGKVDRPIGRDARVPVRMSVERPIAPKPAITHY-------APLRRGRAPDGPVTEVACRLETGRTHQIRVHLASLGHPLLADTLYG-------GRLTAGATRQMLHARALHFDDPGGGGPAAFRADPPDDMRQVQEALQW------------------------
>UniRef50_B0T2G2(54-274:286) Pseudouridine synthase n=6 Tax=Caulobacteraceae RepID=B0T2G2_CAUSK   E=9e-15 s/c=0.38 id=37% cov=82%
---VIHEDDSVFVLNKPAGLSSQggRIQAHTLDDLLWALARRDRPRPRLI--HRLDRDTSGVILTARTKPAATFLGKALMGKRFRKTYWAIVTPGAPEPrgGQIDSPLrRESIGREAYMRVCEADHPdaETARSRYRTLAATEG-----------AALVELSPDTGRMHQLRVHMASIGRPIAGDSRYG-------GALMLGgapVPRLMLHAANLVFPHPEGGE-RRISAPIPDDMRAILAKLG-------------------------
>UniRef50_Q3A3D8(67-284:301) Pseudouridine synthase n=2 Tax=Desulfuromonadales RepID=Q3A3D8_PELCD  E=9e-15 s/c=0.38 id=33% cov=81%
---ILLRDRYLVVVNKPPGINSQPTPARYKGTLyeALLRLLDDPYNKgrkpSLGMVQRLDRDTSGVMIFSIHARAHKSLSDIFAARRVQKHYLALVAGC-MQAPQGEFRSLLARQHRTNLMKSVARGGKEAVTRYRVI--------------EKFGdaeLLEVEIPTGRSHQIRVHFAEAGHPLLGDIRYGGPDRWRG----VDVPRQMLHARRLELLHPISKEPLNIEAPLPQDFLKLL-----------------------------
>UniRef50_UPI0001C42CC7(105-316:322) hypothetical protein BpOF4_01845 n=1 Tax=Bacillus pseudofirmus OF4 RepID=UPI0001C42CC7  E=9e-15 s/c=0.39 id=33% cov=80%
-LDIHYEDDHLLVINKPQGMptIPSREHPSRTLANAVMGYYESHHIPFTFHAvNRLDRDTSGLLVVAKHGLAHDQLSKGQRAGKLKRYYLALAEGFVQpREGTIHAPIKRRPSSIIERMVAADG--QEAITHYKVIND-----------NQAYSEVEINLETGRTHQIRVHFAHLGHPLLGDDLYG-------GSIEL-LARQALHCQRVELIHPFTGKHLHFSAPLPKDLIEV------------------------------
>UniRef50_C2L1H2(90-320:335) Pseudouridine synthase n=1 Tax=Oribacterium sinus F0268 RepID=C2L1H2_9FIRM  E=1e-14 s/c=0.36 id=30% cov=82%
-LDIVYEDRDILLLDKPARLPCHPSP-GHFEKTLAGAIVFYQMQNSSASSfvchfiHRLDLDTSGLILLAKNRLAASVLNKDMKEGRIQRSYLAFCQGnpeFSLGE-IQGFTRLEEKKKKEFNYAFAISAPIARVEEEKMLRTVNFQKgqealsyfnVLNYFPEKNYSLLQLQLATGRTHQIRVHLSYLSCPLLGDSLYGN-GEESVFSQNIGLSRQALHSYSISFTHPIRKEKM-------------------------------------------
>UniRef50_Q7UHX8(79-317:334) Pseudouridine synthase n=1 Tax=Rhodopirellula baltica RepID=Q7UHX8_RHOBA  E=2e-14 s/c=0.34 id=38% cov=80%
-LDILYEDDGLVVINKPAGMVVHPArgnWTGTLTSALAfrFQSLSDVGGpTRPGIVHRLDRDTSGVIVVAKNNAVHLNLAAQWHDRLVQKEYTAITFGRLdrdrdwIHASIGRHPYQRDKQAIREGHATS----KTASTFY------EVVERHGR--VTR---VDVRPKTGRTHQIRVHLAHIGCPILCDrlyGGHSELSRSQirrlagtevatpgvkptPEGEEILLSRQALHAKALTFTNPQTGKEMTLTAPL-------------------------------------
>UniRef50_C5RBB6(79-294:305) 23S rRNA pseudouridylate synthase RluD n=1 Tax=Weissella paramesenteroides ATCC 33313 RepID=C5RBB6_WEIPA  E=2e-14 s/c=0.38 id=35% cov=80%
-IKILYEDENWLVVDKVAGVTSVPGKADRETTMVnrvkgyLISEGAEDLVPHVVT--RLDRFTSGVALLAKHRFAHGLLDKQLQTHTVDKRYYAIVDGIVPDDhGFIDAPIGRMDNDFIRREVRADG--RPSQTEY--WVVNRMPNQT---------LVKVQLHTGRTHQIRVHFKYIGHPLIGDEIYG-------GPMDRGIERQALHAYWLEFYDPFSEIKRHIQSPLPEDLKQIL-----------------------------
>UniRef50_C6D874(113-330:332) Pseudouridine synthase, RluA family n=2 Tax=Paenibacillus RepID=C6D874_PAESJ  E=2e-14 s/c=0.37 id=34% cov=81%
--EVLYEDDFSLVLNKPAGMPVHEShsgqtgTLDEAAARWLLEQGDPLPVRHI---HRLDDDTSGPVLYSKNDLAQWVLDEAMREKRIDRRYLAVVQGKVKKSSgTVNAPIGK--DRHHSSRRRVTPGGDLAITHYETIRAF-----------SDATLVRLQLETGRTHQIRVHMSHLGHPLLGDKLYgGDTRL---------LQHQALHGERLLFPHPWTGELVEAAAAKPEWLVNLLDKLGGR-----------------------
>UniRef50_C9M7B4(78-298:301) Pseudouridine synthase n=1 Tax=Jonquetella anthropi E3_33 E1 RepID=C9M7B4_9BACT  E=2e-14 s/c=0.37 id=33% cov=82%
----VYADDWLAVVEKLAGIAVHPGAGRKDGTLVngLVKTFGPLPGAGLrpGIVHRLDIGTSGLMVVARTPQAYLFLQREFSQRRVEKTYLALVHGWIpASQGTLDGPIgRSRYDRL--KMAVRADG-RRAVTRYRTLWT-----------RGSLSLTACRIETGRTHQIRVHMASIGCYLDGDRLYGPKDVSR----HFLEGRVFLHAWRLSFHHPSDGRTMNFRSPLPDELIGVLKK---------------------------
>UniRef50_D1RB31(87-318:319) Pseudouridine synthase n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1RB31_9CHLA  E=2e-14 s/c=0.35 id=33% cov=86%
-LNILYEDEHLLIINKPVGMVVHPApgnWTGTFVNALLYHCGYSLSDASVDSirpgiVHRLDKETSGVLVAAKTLSVQQKLMELFAARQVYKEYWAICLGN-PGNCELNWPIGRHPIHRKQMTVREDG--KEALTFCETLEV-----------GNEICLAKLILSTGRTHQIRVHLKHKGHPILGDSIYGSKQVNM----RYRAERQMLHARKLAFIHPITQQKIEVEAPLPADMEECLRK---KAMLERTEK---------------
>UniRef50_P59838(86-316:321) Ribosomal large subunit pseudouridine synthase D n=3 Tax=Gammaproteobacteria RepID=RLUD_BLOFL  E=2e-14 s/c=0.35 id=32% cov=82%
-LNIIYEDNDILVINKASNMVVHpgighyqgtvlNALLYRYPSIL-------KISKQAGIVQRLDKDTTGLMIIAKTVSAYDNLLRSFKLRKVVKEYDAIVYGKFTSNAgVVNQPMRRHFAK--RTFMSVHYTGKSAVTYY---SVVEEFKAHSR--------VRINLKTGRTHQIRVHMAYINHPLVGDQKYKgnfsvfDIKKMSDELNNYLLdfNRQALHACTLQLLHPITQVQMKWNAPLPQDILQLIA----------------------------
>UniRef50_C0QAZ3(81-305:313) RluD1 n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QAZ3_DESAH  E=3e-14 s/c=0.36 id=30% cov=83%
-LDFLHEDQWIVVVNKPAGMVVHPGAGNSSGTLLnaLLHHFPSLTDTHCdpplrgGIVHRLDKDTSGTIVVAKSKKAYEFLQKEFRFRRVEKRYIALATGIITEtQGRITLPIGRHPIH-RKRMAVNTERARPAETLWRVLGQM-----------AGHTLLDVGLKTGRTHQIRVHFRALGHPLAGDRVYGF-----RGKQSARAPRQMLHAGTLGFRHPWSGKRVEFTAPLPEDMVEVLERL--------------------------
>UniRef50_B3PEU4(123-342:349) Pseudouridine synthase n=18 Tax=Gammaproteobacteria RepID=B3PEU4_CELJU  E=3e-14 s/c=0.37 id=31% cov=83%
---VLFENEGLLVINKPPGLAVHGGSGVNLGLIETLRQMRPE-ARYLELVHRLDRDTSGCIMVAKKRSYLRHLQAALRdkvEGQIEKVYCALVVGhWPARLHQVNAPLLRTEVGADERYVRVHPDGKPSLTLFNVIQ---------RY--QGFTLVEARPVTGRTHQIRVHARHAGHGLVGDEKYGDDDINLH-MRNQGIKRLFLHASSLGFCLPGEAQMTWVEAPLPQDLAQPLS----------------------------
>UniRef50_C6J215(83-305:310) Pseudouridine synthase n=1 Tax=Paenibacillus sp. oral taxon 786 str. D14 RepID=C6J215_9BACL  E=3e-14 s/c=0.36 id=34% cov=81%
-LSLLYEDDFCLVVHKPAGLKVHpdgneggasrRDSAPPDTLANRVAGWYASLGQPIAAAhiHRLDEYTSGPVLFAKNEYAHLKLDEAMSRKEIGRTYIAFVQGVVSSAlKIIDQPIGR--DRHHNQRRRVSPTGKPAITHVELMEV---------YPKHEVSLVRLTLETGRTHQIRVHLSAAGHPLVGDALYG-------GSTKW-LPYQALHGERLVFPHPLTGETVE----LDDPWPSAIIQL--------------------------
>UniRef50_UPI0001C37137(92-321:338) ribosomal large subunit pseudouridine synthase D n=1 Tax=Chlamydia muridarum Nigg RepID=UPI0001C37137  E=4e-14 s/c=0.35 id=32% cov=80%
-LDKVYEDNMILVINKPRNMVVHPAPGHVQGTVVhaLLHEIGERLKQEFpeepwrpGIVHRLDKDTSGLLITVKTRRAKAVYSELFSSKQMKKMYIAICINSPAQKhihtRIARHPVKR---KEMTVLSKDTEGGKEAITHCHVLAS-----------NGRLSVVALYPETGRTHQLRVHMKHLGTPILGDPVYGVPSINF----RYGLDKQQLHAYSLVFTHPESAERVELVTKLPDD----------------------------------
>UniRef50_C7PP03(7-235:247) Pseudouridine synthase n=1 Tax=Chitinophaga pinensis DSM 2588 RepID=C7PP03_CHIPD  E=4e-14 s/c=0.35 id=36% cov=81%
---IIKETADFVILNKPAGML---TIPDRhDNQLDSLQGLLKKHYGEIFTVHRLDKDTSGVILFAKNEVAHKYYSQLFEGRNVKKFYKGLVNGQLhpetgsVDEAIMEHP------TIKGRMVTNRKG-KNAQTDYQVLEAFGL-----------YSLVQLQIHTGRTHQIRVHMKHLGHPIAVDELYGTaapvylsaIKKNyklgkRVEEERPLLSRLGLHAWQLQFKDQ-QGEENVIEAPLPKDIQAVVTQL--------------------------
>UniRef50_A7HV45(226-463:482) Pseudouridine synthase n=56 Tax=Alphaproteobacteria RepID=A7HV45_PARL1  E=5e-14 s/c=0.34 id=35% cov=83%
-LEIVYEDADLIVVMKPAGLVVHPAPGNPDMTLVnalvahCGETLSGIGGEkRPGIVHRLDKETSGLMVVAKTDRAHQGLSAQFAAHgrdgKLTRAYTALTWGVpQTRKGTVDANIARSShnrSKMATVRDRgEETGGRIAITHY----TVKTDYADG-----LVAEVECRLETGRTHQIRVHMTALGHPLLGDATYGTGMKSRksklSPEAQAALERLnrqALHAHHLGFEHPVAGEKMSFDAPLPE-----------------------------------
>UniRef50_B0TWR8(90-302:309) Pseudouridine synthase n=19 Tax=Francisella RepID=B0TWR8_FRAP2   E=5e-14 s/c=0.38 id=29% cov=82%
---ILYETDDYIVVDKPSGMAVHGGSGVNSGLVERLRQLRPKV-RRLDLVHRLDKETSGCVLLAKKHSSLVYFFDIFKERKVNKIYYALVHGhWDEKVDAIDLPLSRTETKDGQRIVKVDKREGK-----RALTRILAVQKIG-----DYSLLEIKLETGRTHQIRVHTRAMGHPIVADKKYGYMVDDKKLLAK-GVDKLLLHAGKLEFYDEKQQKLISIEAKLDSRF---------------------------------
>UniRef50_D1PCC3(131-376:387) Pseudouridine synthase n=1 Tax=Prevotella copri DSM 18205 RepID=D1PCC3_9BACT  E=6e-14 s/c=0.33 id=34% cov=84%
-INVVYEDDQLMVVNKEAGMVVHpgagnfhgtliqaVAWHLRDMPEF------DANDPEVGLVHRIDKDTSGLLVVAKTPTAKNALGKQFFNKTTHRSYNALVWGNIVEdEGRIEGNIGRDpKNRLRMKVFDPDSGiGKTAVTHYKVLE---------RFGYTT--LVQCVLETGRTHQIRAHMKHIGHPLFMDETYGGteiLRGQRSSSYKAFIQncfklcpRQALHAKTLGFVHPTTKQQMD----FDSEWPNDFRQLieKWRGFI--------------------
>UniRef50_C6J8T7(107-331:349) Putative uncharacterized protein n=1 Tax=Ruminococcus sp. 5_1_39BFAA RepID=C6J8T7_9FIRM  E=9e-14 s/c=0.35 id=34% cov=80%
-LNILYEDTDILAVDKPAGMVTHPTGMHYTDSLsnLVAGYFREKNEQvCVRPVGRLDQETSGIVVFAKNQVAASRLQSVKSPCKIHKQYLAAVSGTLPVDMpgvwhTLDLPLMQDPEnhlkmKTAADLSLHSSAlsgkIKTAVTHYHTL-----------FSSQDWSLITLKLDTGRTHQIRVHMASTGHPLLGDTlYHSDDKISSCAS----FSRAALHAWKVSFQHPFRDEMLLLEAPL-------------------------------------
>UniRef50_B4U613(79-303:308) Pseudouridine synthase, RluA family n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U613_HYDS0  E=9e-14 s/c=0.35 id=30% cov=83%
-IDILYEDNDLAVVVKPSGMPSH-TGPGHDENTLVNALLAKFGDLSVIggverpgIVHRLDRYTHGLMVIAKNDVSHQKLSLMFKNKEVDKHYKAIVYGIsrFKEQTIETFIRRHPTNRLKFEVANEGK---LAITKY----SLEKPLKNA-------SLLDIKIYTGRTHQIRVHMSYIGHPIVGDTLYGYKHSYFDKTlEHMIGKRFLLVAYKLSFLHPKSQKPMEFEIDMPDYFKNVL-----------------------------
>UniRef50_Q312A0(119-337:578) Pseudouridine synthase, RluD n=6 Tax=Bacteria RepID=Q312A0_DESDG   E=1e-13 s/c=0.36 id=33% cov=80%
-LEVLYRDAHMLVINKPAGLTVHPAPSCPEGTLVhrllhHFPELEAQEGFRPGIVHRIDKDTSGLLLIALTEKARLALSDAFAGRRIHKEYLALVKGIPEgDSGEIDAPVGRHpTHKTRMAVVR---GGREALSTWRVL--LADPHGGG---GTGWTLVAVRIHTGRTHQIRVHMQHTGHPLWGDALYGGMpgreELQTTPALAQTATRQMLHAWKISFDHPVTGAPM-------------------------------------------
>UniRef50_C1FEQ4(103-354:357) Predicted protein n=2 Tax=Micromonas RepID=C1FEQ4_9CHLO   E=1e-13 s/c=0.31 id=33% cov=84%
-LDVVFEDDHLVVVNKPPGMVVHPSAghaggslvnallfhcnerSNRGDDASKMIDV-----PRLGVVHRIDKGTSGLLVMAKDAAAQAGLQTQFANRSVRRRYLAIVLGTpARESGRIDAPIGRDpADRLKMAIVRGATGRQ-AISNFG---------VRARLVRGNASLVEWQLETGRTHQIRVHAREMGHPIVGDEAYGGGGSaaaeflRRDGAMSAAaareivakCARPMLHARSLGFRHPVTGEEISFAVEPPPDFVDAFTEL--------------------------
>UniRef50_A4WSV2(90-333:349) Pseudouridine synthase n=41 Tax=Alphaproteobacteria RepID=A4WSV2_RHOS5  E=1e-13 s/c=0.32 id=34% cov=82%
-LSVVWEDADLIVIDKPVGMVVHPApgqWTGTLVNALLHHCGASLSGiggeKRPGIVHRIDKDTSGLLVVAKTDRAHQGLAAQFEAHTVERRYLALVHG-VPEPSDPRLRGIRGVSfepggvlRIATGIARHRtdrqrqavtfEGGRHAVTRARLLERFGTPPAA--------ALVECRLETGRTHQIRVHMSHVGHGLIGDQTYGGRRKLSAKAvgaeaaqAAEAFPRQALHAATLGFCHPVTGEDLSFESPL-------------------------------------
>UniRef50_Q2RQY9(96-315:330) Pseudouridine synthase n=3 Tax=Alphaproteobacteria RepID=Q2RQY9_RHORT  E=1e-13 s/c=0.36 id=32% cov=85%
---ILHEDAHLIVINKEAGLAVQGGTGTPHHLDGMLESLADG-GETPRLVHRLDKDTSGVLVLARTQAAARALTSAFRSREALKVYWAIVVGRpPMLQGTIKGALAKVAGGRGERMEINEEEGKRAVTDFRVVDQAAKACA----------WVELHPRTGRTHQLRVHCLEMGTPILGDGKYGGPGAFLEGTEL--PKRMHLHARALALPHPAGGV-LEIIAPPPPHFVESLKTLGF------------------------
>UniRef50_D0LGK2(70-303:304) Pseudouridine synthase, RluA family n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LGK2_HALO1  E=2e-13 s/c=0.34 id=29% cov=84%
-VRIAYEDAHVVVIDKPVD--VSSVPYERRETGTAMDLLReawrklrpDAGRTPLHVVHRIDKATSGLLAFAKTKRAELGLAAQFRQHTLERAYLCVAHGAVRAQRIESRLVRDRGDGLRGSTRAPNQGKR-AVTHVEVLEEL-----------ARASLCQVRLETGKTHQIRIHLAERGHPLVGERVYKRDAEFR-GHTLIDAPRLMLHAATLGFAHPITGERVFVESPLPENFAAVLARL--------------------------
>UniRef50_A7I2U9(90-342:357) Pseudouridine synthase n=23 Tax=Campylobacterales RepID=A7I2U9_CAMHC  E=2e-13 s/c=0.31 id=29% cov=89%
-IEILYEDDDLLVLNKPSGVVVHPAksvkeptlaeWLKQKKYMLSSINGDERAG----IVHRLDKQTSGAILVAKTDFAHVKLAAQLKDKSMGRIYLAFLDLALKENVCVDRFIARNPSNRLKKAVVppNENGARSAKSAFLNIANDTIlqnfkPLNFSQ-NQTNFNLIAAKLFTGRTHQIRVHLSSINRHIIGDFLYG------FKSDFDKIKRIFLHAYLLYFTHPRTNRQILISAKIPSEFKNLIEKSDFKDeiyekILPSN-----------------
>UniRef50_C7MN62(82-319:347) Pseudouridine synthase n=8 Tax=Coriobacteriaceae RepID=C7MN62_CRYCD   E=2e-13 s/c=0.33 id=30% cov=87%
-LDVRFEDRWMMAISKQAGLCVHPAPGHEGGTLVnalIYAYGRDSLA-HVqgddrpGIVHRLDMDTSGLMMCAKDDTCGMALQDLVRDHKVDRRYLTLVHGNIaFDTGQIDEP----IGRVGDDRLRMKISYRPTARNALTTFTVLERFEAGR-ADNGYTLLECRLYTGRTHQIRVHMEFIGHCCVGDPLY------RWGNEQVNLElsRQFLHSYSLSFNHPMTGDDIALVDGLPPDLFGALRSLEDRSM---------------------
>UniRef50_A8IAL9(148-370:384) Pseudouridine synthase n=2 Tax=Xanthobacteraceae RepID=A8IAL9_AZOC5   E=2e-13 s/c=0.35 id=31% cov=85%
---ILFEDKDVLVLNKPSGIAVQGGSGTFRHIDGMLDALRAKDGQKPRLVHRIDKDTAGCLLIAKNRLSAAQLAKNFRSREARKIYWALVPGVPKprQGRISTYLAREEAEERMRVARHGEEDASHAVTYY---AVVE-------HAAQKMSWLSLKPVTGRTHQIRAHLAHIHHPIVGDPKYFNIENWELPG---GLQnRLHLLARRLVIPHPRGEGMIDVSAPLPPHMAQSWAVLGF------------------------
>UniRef50_Q28C59(50-308:324) RNA pseudouridylate synthase domain-containing protein 4 n=1 Tax=Xenopus (Silurana) tropicalis RepID=RUSD4_XENTR  E=2e-13 s/c=0.30 id=33% cov=89%
---VVREDPELVLVNKPHGLPVHgGPTVERSVASLLPALAKHHFGwkaEPLKLCHRLDRDTTGALILARTTEAAERVQQALREREVHRVYWALCLGTPSpREGILDIPIMEKETSGPQKHYKMALSPRFRVSEEGAVERVRVPrsahEAVTRYRTlgaaSGASLVELHPITGVKHQLRVHLAlGLNCPILGDHKYshwGRLAPQKppdSVLRALGLTvpqartlSLHLHAVQLTLPSSDGSTPIVLQCPLPYTFRKTLRKL--------------------------
>UniRef50_C5ZWU1(67-307:319) Pseudouridine synthase n=2 Tax=Helicobacter canadensis MIT 98-5491 RepID=C5ZWU1_9HELI  E=3e-13 s/c=0.32 id=30% cov=86%
---ILYEDEDLLILNKPINLIVHQTHQDDSQ-----YTLQDWLQENNFSlsnlgdsyrqgiIHRLDKTTSGAIVIAKNNYAHEILSQQLKSKEMGRYYVCVIDSPLKQNILIDAPLI--------------RHPKNRLKYIP--TTKDTPLSkeakTAFFKIINNDKIELigaKLFSGRTHQIRAHLSKIQRHILGDVFYG-YKGNYTA-------RILLHSHLVYLTHPTTKQRLEIYAPLWEDMLLFLHQEFYSSQSYENFAKNFKIPLEQ------
>UniRef50_A4S1L0(12-232:243) Predicted protein (Fragment) n=1 Tax=Ostreococcus lucimarinus CCE9901 RepID=A4S1L0_OSTLU  E=3e-13 s/c=0.35 id=32% cov=80%
-LDVVFENDEFLVVNKPPNLRFHPNH-RFEGNSLLSRALHHMDGATPYIVHRLDMDTSGVAVFVKKQHLVANVAGQFQEKTAKKTYLAVSVGvvppdcgdsFIVDAPIGDHGIVQEARTV--DFSGEGKDAR---------TTCEI-IARATPPAAVAALVRVTPLTGRTHQIRVHLAHAGLPIVSDALYGPhLRwkpyDDWGGA--LSIRRQALHAFNLELKHPETGESLTFQAKM-------------------------------------
>UniRef50_Q8EWS1(72-297:298) Pseudouridine synthase n=1 Tax=Mycoplasma penetrans RepID=Q8EWS1_MYCPE  E=4e-13 s/c=0.34 id=27% cov=81%
-IEIVYEDKYILIVNKPNDIIVHPTSYD-------LSNTLANIIKYIFDSkkikyngdplrmgivHRLDKCTEGLVIVAKSLDSFNAFTKLFLDQKIEKKYLALLHNHLQTRTVeVDAP-IKRVETSTRREVSRDIDAKEARTIFKEI---------NKYKN--FTLAEVELFTGRTHQIRVHAEFIKNHVINDPIYGPKHINKTTK--YG-QYLV--AYKLKFIHPFTQKEVNINLDMPKEFKEYIKKYG-------------------------
>UniRef50_C1E0I0(71-300:318) Predicted protein n=2 Tax=Micromonas RepID=C1E0I0_9CHLO   E=5e-13 s/c=0.33 id=32% cov=80%
----LWEDEHLAVVSKPAGMLTHPNEASGGATRTLVEALLDAFGDEGLSAingadargivHRLDKPTSGAMLVAKTDLAHAMCVAAWYQRKVTKTYLALVEGvpgRRRGRRRGDDGDAMEGTCVAPADGR------PARSDWRVVETFGE--EDGDDAEQLCSLVEVTPRTGRRHQIRQHMGmALDAPLVGDPlyRRGKRPNTPATAAPFLVGKpgsvLFLHSAALALRHPVTGEALSF-----------------------------------------
>UniRef50_A3DDK9(79-313:318) Pseudouridine synthase, RluA family n=3 Tax=Clostridium thermocellum RepID=A3DDK9_CLOTH  E=5e-13 s/c=0.33 id=31% cov=84%
-IDIIYEDEFLIALNKQPGIVVHPTCSHPGgtlANAVAFHLQKKGIVKKIRPVIRLDRDTSGIIIFAKNPYCQEFLIRQMNDKTFIKEYIGIVHKVLeNDNGTIDLPIARKPGSIMLRHISPDG--DPAVTHYTVLERLNG--AT---------LVKFRLETGRTHQIRVHCQAIGHPLLGDTlypfedtpyslsgNNPHITQANTPSITSGiITRQALHSQRAVFLHPFTKKILEITAPIPEDMKSAL-----------------------------
>UniRef50_Q1D114(80-301:306) Pseudouridine synthase, RluA family n=6 Tax=Cystobacterineae RepID=Q1D114_MYXXD  E=7e-13 s/c=0.35 id=34% cov=82%
VLPVLHDDSALVIVNKPPGIVVEPEG--RAASVVGLLAAQrppfDVEGlAQPGVVHRLDRETSGCLAFARTDTAAAALLRSFQEKRVDKRYWTLVLGQPPAQGRLEGP-----------YARDPADPRRFTTRVpsarRAALSFEV-----RERFADAALLEVDLDTGRTHQVRVQLSEAGFPVLADSLYGPP-EARAHAAARALGRQALHAFTLELPSPATGQPVRVEAPLPEDFQRAL-----------------------------
>UniRef50_Q2S3B7(74-338:349) Pseudouridine synthase n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S3B7_SALRD  E=9e-13 s/c=0.29 id=36% cov=82%
-LDVVHEGDDLLVVNKPAGMVVHPAPGHRSGTLVHAllhhvdggevaadderdEVSEDEVGLSLVNAlpqspdhpvvrpgivHRLDKGTSGLLVVAKRGRAHQPLAEQFKAHTVDRRYRAIVWG---------------------RFAPSDGTIEGAIgrdPHHRQRMAV-VPEDEGKWARTHYetvethahtSVVEFELETGRTHQIRVHARAQGHPLLGDPKYGGQRvryGTQSGTRRTFYDQLFetlphpaLHAYRLGFDHPTTEERLRFEADPPPAWRRVLREL--------------------------
>UniRef50_D0MJ49(86-350:355) Pseudouridine synthase n=2 Tax=Bacteria RepID=D0MJ49_RHOM4   E=9e-13 s/c=0.29 id=38% cov=83%
-LDIVYEDPYLIVVNKQAGLVVHPARGNRSGTLVnallyyigsgpvrfdeeDDLPEDDEIGLSMVStgpteakleaprpgiVHRLDKDTTGLIVVAKDDVTHTGLARQFEHRTIARTYLAIVWGvpdpprGRIEAAIGRDP----RDRQRMAVVPDDRGKR-AVTHYEVVEA--LPAA---------ALVRFKLETGRTHQIRVHARHIGHPVLGDPTYGG-RTIRYGPhtprrrafydQLFArLTRQALHAHTLGFRHPRTGEWLEFEAPLPEDMACALEQL--------------------------
>UniRef50_Q7UQ77(29-248:256) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Rhodopirellula baltica RepID=Q7UQ77_RHOBA  E=1e-12 s/c=0.35 id=31% cov=80%
-VDVIYEDNHLLVVNKPTKLatmgaagqpTLHSLGCD-----YIRRTCNKPNKVYLGIVSRLDSMTSGVIVMARTSKAASRLTPQFANHSgdgAKKTYLAVVSGRVEQQQ----------GTLVDDVYKDDAAHRMRVAHHSRSDAKEARLEYEVLGCDReLTLLMVKPLTGRKHQIRLQWAEVGFPILGDTKYGSERSWPTG--------IALHSWRLSIMHPTKKERMTFEAPIPDAWASRL-----------------------------
>UniRef50_Q7XA65(76-315:322) RNA pseudourine synthase 1 n=12 Tax=Magnoliophyta RepID=PUS1_ARATH   E=2e-12 s/c=0.31 id=36% cov=80%
--DILYEDEYLMAVNKPKG--VYCEAVLRSAPQIVLDS-----SSEYHLANRLDRDTSGVMIITKSHKVAAKLVKAFTEHKIRKSYIALCIGsspnwrrvtvssghgrskhgaWRV-YAALDVGRVlpggsfvrdmETTFEVVSVNSVKNESCELEDVNHVIVAEGERELSCGGDDDDVVVVVRAFPRSGRTHQIRLHCQYLGIPIRGDVKyHGVYEWNgRTFEGH------ELHAECLSLDHPVTGDSIVIRAPL-------------------------------------
>UniRef50_D2LES8(96-319:326) Pseudouridine synthase, RluA family n=1 Tax=Rhodomicrobium vannielii ATCC 17100 RepID=D2LES8_RHOVA  E=5e-12 s/c=0.33 id=30% cov=86%
---IVFENDEMFILNKPFGIAVQGGTKTTRHIDGLLAGMADRFgGERPRLVHRLDRDTTGILAVAKDRQTAARLGRLFQTRSVQKIYWAITRGIPKpTQGKVEAALVKASGPDGDRVRKARPGEQELAQHATTFYSVIDRAAN-------MAWVSLKPVTGRQHQLRAHMDILGTPILGDQKYGD--GTEIPIENIE-RKLHLHARRLTLKDPKLGE-IDISAPLPSHIAQTFELLGF------------------------
>UniRef50_C3XV24(70-329:335) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3XV24_BRAFL  E=6e-12 s/c=0.28 id=36% cov=81%
----LYDEGDIVAIEKPYGVPVHggpgMGVSIADSLPLLQQALKT---DRLYLVHRLDKETTGVMLLAKTDDMARQLHSLFRLRKVIKKYWVLTMGVPShEEGVVDIPIKElevtaqgrphhrmvcvpeysEETKLIVKKKRKSSDAQIAITNFRVLDS-----------CGSCALVECQPETGVKHQIRSHLSYgLGCPILGDHKyshHSKLAPQRLPTgmlERFGIQQpkarylpMHLHARQIVLPGFRDGRSLYFTARLPDFF---------------------------------
>UniRef50_A5EXY5(94-310:313) Pseudouridine synthase n=2 Tax=Cardiobacteriaceae RepID=A5EXY5_DICNV  E=6e-12 s/c=0.34 id=33% cov=82%
---VLYEDDHFLILNKPAGIVVHGG---SGHEFGVIDVVRSIWGEnYAELAHRLDGDTSGVLVLGKHRQALNAFQTAMNEGTVEKRYWALVDGvWTREEAEVVVHLTKAPLNVREKMqVSELENAQFARTWF--------------YVLQRWqdaTLMEAVLDTGRTHQIRVSAAHCQHAIAGDKKYGK-REFNDLVRKKGFHGLFLHAREIKFC--YQNQTIHVMAPLTEAMQQLLEHW--------------------------
>UniRef50_C1A885(83-308:329) Pseudouridine synthase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A885_GEMAT  E=6e-12 s/c=0.33 id=31% cov=82%
-LDVVYEDEHLLVVDKAAGMVVHpapgnwtgtlvNALLGRGEPLAEGGG-EDRAG----LVHRLDKDTSGLLVVAKSDAAHRTLSSALAARQVTRRYAAVCWGHLAEERItVEKPIARDpRDRTRMAIVQSGKASRTDFTRLARFDSVD--------------LLRAHLHTGRTHQIRVHLASTGHPVVGDDTYGGGGGRRLAL--LPPRRHFLHAAWLRFRHPISGDLIDLRSPLPADLRTSLAALG-------------------------
>UniRef50_A9GBV3(90-336:345) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GBV3_SORC5  E=7e-12 s/c=0.30 id=34% cov=85%
VIPVVYEDEHLLVIDKPAGLVVHparghasgtlvNGLLALPGFALAPADPRDPMG-HVrpGIVHRLDRGTSGLLVVAKDEPTREALKDRFARHAIEREYAAIVAGEARDATYDTLHGRHPTDRLrftswirggAGAPGSHVAAPRRAVTHVRVIERL------GDAAT----VVACSLETGRTHQIRVHLAERgRTPVLGDPLYGKPPKKpavRAIAEELGRQ--ALHARVLGFIHPATQKPVRWESALPADMRKALDQL--------------------------
>UniRef50_A4S7H5(44-306:318) Predicted protein n=2 Tax=Ostreococcus RepID=A4S7H5_OSTLU   E=8e-12 s/c=0.28 id=34% cov=82%
----VYVDDDVYVLNKPAQTYVHdierlveRGMVKCDDATTVdnRATTRDvpfNASESARVVHRLDRDTSGCLVVARNRDAIRSLSAQFADGTVQKTYVALC------AATADYDGVEDHRRVFTGWGRAKYGlfrlydaadigralpgnKKVKVKHAETTIIVERVITDGvalRFcepPTAddadrrrhRVALARCSPLTGRTHQIRLHCASLGLPLVGDVRYgGPIAATRDGPidAPFSARRVagaLLHAERVAFRHPKSNLRVDVHA---------------------------------------
>UniRef50_Q54N28(430-709:718) Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum RepID=Q54N28_DICDI  E=8e-12 s/c=0.26 id=33% cov=86%
---VLYKDEHIIVLNKPQGLSVQGGTGLNKHLDMMLSHLRFEKDENPKLVHRLDRNTSGILILGRSKLAASAMTKKFElklvkenkkdkddnnnnknnknnnkndskrlfrekevfnnnknkdeenenySKGIKKTYWALLGSTPTpKEGRIRAPLkkvvVGGFEKVVPTLTTGD-GAKIAITEYKVLES----------SLTKHCFISLWPETGRTHQLRVHCASvLNTPIIGDPKYGDKESDSNLKDLLPYpSKLHLHARRIEFIHPFTNKKIDISAPLPRELVQNWKTMGF------------------------
>UniRef50_UPI000185C0B7(98-322:342) 23S RNA-specific pseudouridylate synthase n=1 Tax=Corynebacterium amycolatum SK46 RepID=UPI000185C0B7  E=9e-12 s/c=0.33 id=37% cov=81%
-MPIVFQDDNLVVVDKPSFLATMPRGRHITETAVV--RLRRELGNpELVPAHRLDRLTSGLLIFTARREVRGAYQGLFASGEVTKRYHALTSPTPIaggaSEALPETPL--ELRtrqhKIAGQMqAYTLEGEPNAHTIIEHISLVDVPSdADGLAADSgRVALWQLKPITGRTHQLRLHLSELGFPILGDQYYPEIlpleAENTS-------EPLHLVCVEMSFADPVTGEQRTFHS---------------------------------------
>UniRef50_B1C9B9(81-306:307) Pseudouridine synthase n=1 Tax=Anaerofustis stercorihominis DSM 17244 RepID=B1C9B9_9FIRM  E=1e-11 s/c=0.32 id=27% cov=84%
-LNIIYEDKNIILIDKPSGILSQADGSSKEDIVSNLISYLNSKSTGIVT--RLDLNTSGIVLAGKNRRALMLLNEMSKNKLIDKRYLTLVRGDFDREG-----------KVTHYGIKDNKENKLILGNKKVDGSFEVSaefIIKKRYKY--HTLLEVRLITGKTHQIRSQLDKMGFPVVGDRKYNKSKQC-GNKDDFKINRQFLHCYKLTLKYSekykeIVTEDKTFYSDLPKDLKNVLKELG-------------------------
>UniRef50_C0QPR5(85-303:319) Pseudouridine synthase n=4 Tax=Hydrogenothermaceae RepID=C0QPR5_PERMH  E=1e-11 s/c=0.33 id=29% cov=80%
-VDILFEDEDIAVVYKPAGMVVHPSPGHTSGTLVNallyhFRNISEYGGkERAGIVHRLDKDTAGLMIIAKSEFAHKELQKQFQERTVDKRYIAVVTGIVQNDhGFIDLPIGRSIYN-RKKMGTEATNLRDALTEYW---------VKNRSEKENLTVVDIKLHTGRTHQIRVHFSAIGHPLFNDKVYGFKKsQLRSEKMRSISDQTLYHallAYRIAFDHPRTGEKIDI-----------------------------------------
>UniRef50_C0BNA6(132-372:379) Pseudouridine synthase n=7 Tax=Bacteroidetes RepID=C0BNA6_9BACT   E=1e-11 s/c=0.30 id=31% cov=86%
-LDVVYEDSDLMVVNKPPGMVVHPGHGNYSGTLInaLLFHVKDlplNADERPGLVHRIDKDTSGLLVVAKTAKAMTHLAKQFFDKTSEREYVAIVWGNVEEEQGTVRGHIGRHPKNRLQMAVFPDGDQgkEAVTHYKVMERL-------GYVT----LVSCVLETGRTHQIRAHMKHIGHTLFNDERYGGEKilkgTTFTKYKQFvdnafkALPRQALHAKTLGFVHPSSGELMRFNTPIPEDMVLCIEK--WR-----------------------
>UniRef50_C9RJ15(83-308:321) Pseudouridine synthase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RJ15_FIBSS  E=2e-11 s/c=0.32 id=30% cov=82%
-FETVFEDDEFILVAKPAGVPVHHTG--RIFYNTFAAIIRREFDSETATpMHRLDRDTGGLILFARYGETAARFQKNLDRILLRKFYLAVVRGKFPEgEVECHMPLREDPEDPIRLRMHHREGGKECFTRFKLVRHLDCPEI-----APELSLVEAELITGRKHQIRAHLAEMGYPIVGDRlyyRDGEFYQKLAqGGELtdedikvLGAHNQMLFAYKVELQLPYWKEPRTFES---------------------------------------
>UniRef50_D0LYX0(92-343:345) Pseudouridine synthase n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LYX0_HALO1  E=2e-11 s/c=0.29 id=34% cov=90%
VLDLLYEDDAIAVVSKPAGLPSHplRAG-ERDtlaNALVAHYPECAAIGadpREAGLAHRLDIDTSGVLVAARTQKAWHALRAAFGSGAVEKHYLALTFG-APSSGEMDVALVQRGRRAHPVF-RDDA--GFGGFGGRGERGDALPARTTWRIERRFGpacLLLCRAHTGRMHQIRVHLALAGAPIIGDSLYAPAPETLSAAeredlaalsEHPEATRHFLHASAVTIPHPETGRALRIEAPLPEGRAQFLAELSRR-----------------------
>UniRef50_B2IK20(90-337:350) Pseudouridine synthase n=2 Tax=Beijerinckiaceae RepID=B2IK20_BEII9   E=2e-11 s/c=0.29 id=36% cov=87%
---ILFEDRDLMVLNKPFGLAVQGGSGMTHHIDKMLASLPNERGDRPVLVHRLDRDTSGVLLVAKTRRMAAELGEIFRSRQARKIYWAVVEG-------VPKPAQGRISlYLAKGEGMEDKrGPHGRDAEARA-GLEKMRVAKhgeedARHSVTYYAIVDkvpsrlawlsMKPITGRTHQLRAHAEAIGHPIIGDPKYGlkpkdDPRRNDPNrAIPEGVERkLHLLARRLILPHPRGGI-LDVTAPLPPHMQKTFDLFGF------------------------
>UniRef50_D1N1K3(90-312:321) Pseudouridine synthase n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N1K3_9BACT  E=2e-11 s/c=0.32 id=33% cov=82%
---IAYEDDALLVVDKPGNLCVHPS--GPFFKHTLWHLLSSKYGK-IHLVNRLDRETSGLLVAAKNPKAAAKLGKP--GWPMRKEYLALVFGNFADRIEAYGFLVPDLASVVRKKRRFVAGERPPEGAVRpeSARTVLLPARSGE----RYSLVRALPETGRLHQIRATLFSLGFPLLGDKLYGpddgiflKIRSNAITAadrERLILLRQALHSAKLAFRHPDTGETVAVESPL-------------------------------------
>UniRef50_Q1GB64(79-299:302) Pseudouridine synthase n=17 Tax=Lactobacillus RepID=Q1GB64_LACDA   E=3e-11 s/c=0.32 id=37% cov=81%
-LDIVEETADYLVINKPAGLLSIPSGFHAEDAVInrVLAYFEKQgvnpayVKPHIVT--RLDQDTSGLVLLGKNAIAHDRFS-KLGKDAFIKKYHAIVHGNFAEgdlSGLIDKPLA----RVGDTVKREvNPKGQRALTEYRVLNQV--PGAS---------LVELRLLTGRTHQIRIHMASIGHVLYGDDLYG---------ARDAFARQALNCFYLAFPNPFSGEEREIEIP-DPGDMQGL----WRQLKQE------------------
>UniRef50_A4S8W7(13-253:264) Predicted protein n=2 Tax=Ostreococcus RepID=A4S8W7_OSTLU   E=4e-11 s/c=0.29 id=35% cov=82%
-LEILHEDEEMTCVNKRAGTastpesrvadssaasLVVARWrrrlVDAHDGALASNVV---LGASLvpYVAHRLDLETSGALVVCKNAKAAARAQGAFERREVEKTYLALCRcdefdvsGGGASSGTIDLALAKRDDGARFFVETSSADGKPASTEW-------TIVARNR----RHALVRCRPKTGRTHQIRVHLAAIGLPIVGDAAYGCLDADV-------VDRHALHAWTLRFpAKDFAGVP-RIVAPVPDDFRRACERVG-------------------------
>UniRef50_Q7VI26(89-311:351) Ribosomal pseudouridine synthase n=1 Tax=Helicobacter hepaticus RepID=Q7VI26_HELHP  E=4e-11 s/c=0.32 id=27% cov=82%
-IDIVYQDEDVLIINKPPHLVIHHApsvkeptlvdWLKLNAHILYTLSGEERYG----IIHRLDKQTSGALAIAKSNLAYTTLTKELKSRQMGRYYLAIIDTPLKDNQQVQCFMGRNPHNRLKMSKIHIRSNSPIPKGVRDSKSSFIKIATS--DNGAFELIAIKLHTGRTHQIRAHLESLSRHILGDTLYGYKPQAKT---HYYQDRILLHAYILYFIHPKTQQNCTFKAPI-------------------------------------
>UniRef50_C1N7S8(37-318:360) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N7S8_9CHLO  E=5e-11 s/c=0.25 id=34% cov=95%
-LTVLYEDEHVLAVDKPPGVMTYPAHRLRGGSVVnravhhLRGVTRDGSGGGAgfgfgaatepIAVHRLDLETSGVLMLAKDKPSASALQGAFERREARKTYLAVC--AILEDAANASDESDDDFDFERHPGHRRRERRRRAVHTRGDAGRE--AREHRFTGKRIvgtALVLARPLTGRTHQVRLHLAHAGLPIVGDALYGyddALRPASGGFE----GRMALHAWNLAVKHPRTKNTMRLAVDM-PADMQALSvGLGLRveGVLlgdaaaaaaaaGAAKRTSTSARTGSDG----
>UniRef50_Q38VN9(78-296:306) Pseudouridine synthase n=1 Tax=Lactobacillus sakei subsp. sakei 23K RepID=Q38VN9_LACSS  E=5e-11 s/c=0.32 id=34% cov=81%
-LKIAYEDDHFLIVDKPAfvASLPAPNHPNNTMANFVKQYLIDEqaesLAVHVVT--RLDRDTSGLMMFTKHGFAHSLLDRQLQSKELQKTYIAIASGDMREDlpqhAWIDRPIKRSEEFYMRRVVGE--GGKRSLTEY-------WQAAHGDGAT----LVKLKLLTGRTHQIRVHFASLGHSLIGDNLYGESND--------LLPRQALHCRQLTFYHPFEERTITVKSPVPADFSAVLAQ---------------------------
>UniRef50_Q8D220(84-310:314) Pseudouridine synthase n=1 Tax=Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis RepID=Q8D220_WIGBR  E=7e-11 s/c=0.31 id=23% cov=83%
----IYEDDDILVINKYKDVIVH-PGCDKHENTLLHDILFNYpDSKNLYRAgivHRLDKDTTGLMLIARNSFSQKKLIKLLKLRLINREYRAVLLGKIICDGTVSAPIIRN-SKNRTRMKVHISGKE-SITHYKIIKNF-----------NDFSYVKINLESGRTHQIRLHMSYINHPVLGDFVYGNKKNKYIKTLYksiFNISRHALHARKIKFIHPINNCLMVHKIDLPDDMKILLKNL--------------------------
>UniRef50_Q1WSL9(78-294:295) Pseudouridine synthase n=3 Tax=Lactobacillus RepID=Q1WSL9_LACS1   E=9e-11 s/c=0.32 id=29% cov=82%
-IKILYEDDNYLLVDKPAFVASIPSPLHPNDslvnRVVGYYQIRGYRGIIPHIVTRLDRDTSGIVIFAKHRYAHALLDSQLKEHKISKTYTAILSGILHNNhYIIDLPIgRDSTSLIKRKVLFSEKAKR---------SKTEIFVEERIRDNT---LCKIKLHTGRTHQIRVHCSYLGYPLVSDTLYG-------GTISMPLQRQALHCSEVVFWDQFSSQYIKVKSNISQDMMNYL-----------------------------
>UniRef50_Q2IJ40(100-353:353) Pseudouridine synthase n=7 Tax=Cystobacterineae RepID=Q2IJ40_ANADE   E=1e-10 s/c=0.27 id=33% cov=89%
-LAVLHEDADLIVLDKAPGMVVHPARGTPHSTVVNALLHRlglpaaagpDGALPRLGLVHRLDKDTSGCLVVAKTEAALAALQAQWKGRSVEKVYLALCHGALAAAGRLDTPYGRhPRDRL--RFTGRLASSRRAITEWR-VREAFGPAAS---------LAEVTLHTGRTHQIRVHLSEAGHPLLGDAVYGGTRREarlapddpaRRAAEAVGRQ--ALHALRLGLDHPRTGRRLVVEAPVPADLRAALeilraAQPGNAGPAPRRRR---------------
>UniRef50_D2NPM0(135-370:377) Pseudouridylate synthase n=2 Tax=Rothia mucilaginosa RepID=D2NPM0_9MICC  E=1e-10 s/c=0.29 id=29% cov=83%
-MPVLYEDEHVLAIDKPHFLPTTPRGAYIAQTALTKLRVREQ-NPLLIPIHRLDRPTAGVLLFAKTVEARRPFQMMFQHRRVSKTYRavapVPADPAAAERALSAEGLQvrSHIQKIRDQLQVQQlseeqcaaQGVEPNTLTTAKILQTFTPSAQAvegwrAEPNREWALYDLAPHTGKTHQLRAHLNMLGSPILGDVLYPQVLPDAPDRPEYPLQLL---AYSLHFEHPITGERVDLYS---------------------------------------
>UniRef50_Q2GEQ1(79-323:330) Ribosomal large subunit pseudouridine synthases, RluA family n=4 Tax=Neorickettsia RepID=Q2GEQ1_NEOSM  E=2e-10 s/c=0.28 id=28% cov=90%
-LDVRYEDDCLLVIYKPAGLVVHPGIGNREQTLVNIlehhyptEKLSSLDSSRPGIVHRLDKDTAGFLIVAKTNPAHLSLSQMIKEGVIRREYLALVHSV---PASLSGEIKKPIKRGQRKMMIGRCSGKPALTYYGVIA---------RTVDRKCSLVHCRLGSGRTHQIRLHMKSIGCPVVGDKLYGLNRDADLCAPHHALW-----AYSLQFRHPFTRKNMAFYiepASIIQPFLEKISI--SRSLfvtFPEDRRTIRSAQS--------
>UniRef50_Q03EW7(28-242:253) Pseudouridine synthase n=1 Tax=Pediococcus pentosaceus ATCC 25745 RepID=Q03EW7_PEDPA  E=2e-10 s/c=0.32 id=27% cov=80%
-IDVRYEDADYLIVNKPpflptvqSAANQKDTLVNRVKNYYVKNNYESRV-VHVVT--RLDQDTSGLVIFAKHRFAHTVMDQDLRQRKINKMYLTIVEGTFTNQhGIIETPIQRDPDSFIKRMVAPMGEGKPSLTEYWVEDTFK-----------NFTLLKVKLHSGRTHQIRVHFSSIGHPLVGDELYG-------GMANDILQRQALHCFSLTFKNVFTEKMIDIKTSIPDDMLE-------------------------------
>UniRef50_A9V182(13-261:289) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V182_MONBE   E=3e-10 s/c=0.27 id=35% cov=83%
---VIYEDNHLVALNKWRGLAVQDAAGSPStvlSNVDVFQQNKDGFVPRL--AHRLDQNTTGVLVLAKTAEAVLRLNRLFQLGAVAKTYEAVLAGQVTKPTGTLKGIPELITEEEDANS-ELTSNQPlfktsaswshstAQSHYTVLASAQ--VNDGRPSRTKPWLtrVELRPTTGYKHQLRIQCADgLRAPVLGDKRYGGGQEQvspiilqhlqrhglRTAAHPYGLV-MHLHAKQLVIPgYNWDGSDLVLRATLPD-----------------------------------
>UniRef50_C9RQF0(78-313:424) Pseudouridine synthase, RluA family n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RQF0_FIBSS  E=2e-09 s/c=0.28 id=32% cov=83%
-LNIVYEDDDIVVINKPRNLVVHPG--NGVSKGTLAAALLYHFKENLSTvngplrpgiVHRLDKDTPGLMVVAKNDAAHRHLAHQLETRTLHRTYNALVWGCPRDlEGTIDAPIGRN-PKNRLKMAVV-KGGKESRTHY--VAKQFFAIAT---------LLELQLESGRTHQIRVHSRYTGHPVVGDPLYDgrDESLNRVPplmkpvAEKVleIAPAQLLQAVKIELIHPRTNKKLTFKVPMEEPFANVLK----------------------------
>UniRef50_A8RLV7(1-238:274) Putative uncharacterized protein n=4 Tax=Clostridiales RepID=A8RLV7_9CLOT  E=3e-09 s/c=0.27 id=30% cov=80%
MVPILYEDKDIIVVQKPAGL---ESQVSRGFAPDMVSEIRRYLhnpqdihnhPQGVSTAqppyvgviHRLDKPVEGIMVYALNQKSAASLSAALQAGKIKKSYLAVVCGKPVDKqgTYVDYLRHCKENNTSKIVDKSDENSKKAVLNYRVLEVINNP----KNQEQILSLIDIELLTGRHHQIRVQFAGHATPLYGDERYGGGLSTKSTTmtvdrgrkkSSFGDahRPLALCARRLAFPHPSTGK---------------------------------------------
>UniRef50_B8C2A6(273-592:596) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8C2A6_THAPS  E=3e-09 s/c=0.20 id=40% cov=82%
-LQTIYFDKDIVVTNKPSGLLCvpgvnhYRSLLDlvyevyggganpNDKGISTTQQTTDEsatttleepLQKDSMIAHRLDMDTSGIVVFARTRLAMSKLHKSFrERTGTRKRYEALLVGWLdtatwassaNNSSNNNYLGCNAGDTTADTdlgggeinlplqrdhkhppFMRVStpeseveaamavrdlnhagwkklvaKRPKPSTTQFRILAhEVWM-----DHPITR---VELTPITGRTHQLRVHCAAIGHPILGDPAYGwcgeahpnggfceeVMRQMSPTCAGMELQRdveesvqasgrtMCLHARRLGFHHPATDKYVEFEA---------------------------------------
>UniRef50_C4GBK1(103-339:341) Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles DSM 14600 RepID=C4GBK1_9FIRM  E=4e-09 s/c=0.27 id=27% cov=87%
-LNIIYEDEDILLIDKPAGMPSHPSMNHQKDTLanAVLYYYQKQGIPFVFrIANRLDMDTSGLVAVSKNSLAAARVKQMIDKRQIHREYLCIVEGSFSADSSLAKRDFVKMRYDADGQMIGGRIWAPISRREGSVLERRVNASDGQTALTdfeivqegaKYSLLRVWLGTGRTHQIRVHMNYLGHPLPADYLYHPVYQD--------ISRQPLHSAKLRFPHPVSGRQMCFESRLPADMRHLLDNF--------------------------
>UniRef50_Q9ZL98(78-304:327) Uncharacterized RNA pseudouridine synthase jhp_0682 n=15 Tax=Helicobacter RepID=Y745_HELPJ  E=5e-09 s/c=0.28 id=29% cov=82%
-IEVIFEDEDLLVLNKPPNLVVHKApsvkeptlvdWLKSQNYELSNLGLKERYG----IVHRLDKDTSGGIVIAKNNFTHVCLSEQLKTKMMGRYYIALLSTPLKEekmsvECYLTRNPNNRLKMIALKAAKKEKS-RYSKSEFTSLLTSQ----------NGMDLIGAKLFTGRTHQIRAHLEYLNRHIIGDNLYG-----LNGVLSKEEIRIMLHAYLIEFKHPRSEQKLRFKVPLLKDMLEYLKK---------------------------
>UniRef50_C0WQF4(79-293:297) Pseudouridine synthase n=3 Tax=Lactobacillus RepID=C0WQF4_LACBU   E=7e-09 s/c=0.30 id=29% cov=82%
-IQIVFEDEHFLVVNKLSGIAsvpAHNRANDSLVNRVKGYYQRNHYAnQKIHIVTRLDKDTSGLVIFAKHHFAHSVLDKQLKDHQIKKTYLAIVEGTFSTTHFEIYLPIKRAD--GSLVKRQVGFP----------GKMSITEAWTKQRLRQHTLLKLQIHTGRTHQIRVHMTAIGHPLVGDWLY--------NPEDKSFPRQALHCAGLRFFNPFAGHFVDCRAPLPDDMKTYLA----------------------------
>UniRef50_B1XIP1(60-280:282) Pseudouridine synthase n=1 Tax=Synechococcus sp. PCC 7002 RepID=B1XIP1_SYNP2  E=9e-09 s/c=0.29 id=31% cov=80%
-FQILHQDPHFWIIDKPAGLPVLPAG-NFLENTLLAQLKRQFPDETPVPIHRLGRGTSGLMILGRSPLGRQSLTRQLREHQITKIYRAVIPAG-------DYPDQITITTPIGKIFHPSLGTIFAATADGLSAHSEMRVLERLAKVSR---VEVQIFTGRPHQIRIHMAAMGFPLVGDRLYlpGGLPAIYEDANHSPLPgdcGYSLNAYYLKFQHPHQDKPIDF-----------------------------------------
>UniRef50_B6TXP4(138-423:439) RNA binding protein n=3 Tax=Poaceae RepID=B6TXP4_MAIZE   E=1e-08 s/c=0.22 id=33% cov=86%
-LDIVYEDDHVLVVNKPAHMVVHpapgnakgtlvnailhhckistftclaRSSAgdecpdssDEDTDVFhVDQFAAEDVSSEVRNAlvrpgivHRLDKGTSGLLVVAKDEHSHARLAEQFKLHTIRRVYISLTCGAPNPNS----------GRIEASIAR-DPNNRIRMTAIAGSGHRYARNAASRYKVREVfagggsALVEWRLETGRTHQIRAHAKYIGIPLLGDETYGGtqsmalslLRPRSPSKYHSGLSNLLskvdrpcLHAASLGFKHPRSGKVLEFSCPPPDDFLEVLGEL--------------------------
>UniRef50_Q0C3G8(95-335:349) Pseudouridine synthase n=2 Tax=Hyphomonadaceae RepID=Q0C3G8_HYPNA   E=4e-08 s/c=0.25 id=29% cov=87%
---IIHEDDDMLAINKPAGLAVQ-GGSGQGRHVDGLIAGMDVDGHRPVLVHRLDKDTSGVLLLAKHPAAAARLTELFRSREMDKVYWAVTVGVPSPQAgqircwmVKGVPDINEpsgyrpVDPYATK--RRDGDRERMIRSAQGVEGARHSITDYVVVSTagpKAAWVAMRPETGRMHQLRFHMLEMNTSILGDYKYKSRREVPQGLA----EGLHLHARALIIPREH-GKPIKIVAPLPPHMKETFETLGF------------------------
>UniRef50_Q5Z8P2(140-425:445) RNA pseudourine synthase 2, chloroplastic n=6 Tax=Magnoliophyta RepID=PUS2_ORYSJ  E=2e-07 s/c=0.21 id=30% cov=88%
-LDIVYEDDHLLVVNKPAHMVVHPAPGNANGTLVnailhhckistFTCLARNSIDDECpdssdddidvfdidqFTtgevssevrealvrpgiVHRLDKGTSGLLVVAKDEHSHAQLAEQFKLHTIRRVYISLTCGAPNpNSGRIEVPIARDPNNRIRMIATPGSGHRYA-RHAASRYKVREVFAGG-----GSALVEWRLETGRTHQIRAHAKYLGIPLLGDETYGGtksmalslLRPRTPSRYHCDLSNMIskidrpcLHAALLGFKHPHSGKILEFSCPPPDDFTEVLNEL--------------------------
>UniRef50_C8RQ24(59-294:297) Pseudouridylate synthase n=2 Tax=Corynebacterium jeikeium RepID=C8RQ24_CORJE  E=2e-07 s/c=0.25 id=33% cov=83%
-IPVLYSGSDAVVVDKPHG--LPSTPNGRLLRATAQSLMRVRLQEpELVAAHRLDRDTRGLLVLARNPVTRGFLQTQFQRREVSKTYQALAADipeigsqWqdvqLPMLKIKDDPQVKVVDGERSRL---------TVTRIRKLASSagaeARPVEATRagTPTAVY---ELQPLTGYTHQLRVLMNHLGAPIYGDDTYPEY---RPGA---GALRLRAVAIELALVASLKNrQRIEIERCLEDPWAQWGNWPSWR-----------------------
>UniRef50_C8NY78(108-335:339) Pseudouridine synthase n=1 Tax=Corynebacterium genitalium ATCC 33030 RepID=C8NY78_9CORY  E=3e-07 s/c=0.26 id=29% cov=80%
---VVYEDDAIMVVNKPP-FLATMPRASHITESATVRLRRSTGNEELTPAHRLDRMTSGLLLFTKKASVRGAYQQLFASRAVAKLYEAVaddIGPSLPARPSANSPLVWEHHIVKREGELASSITVDAIPNSLTYVTDITPLQGG---AARY---LLQPVTGRTHQLRVQMHAAGAPIHGDPVYPELLP--ASAEDF-TNPMLLTAVGLAFTDPLTGVKRTFSA---------------------------------------
>UniRef50_B1VE82(143-415:422) Putative pseudouridylate synthase n=1 Tax=Corynebacterium urealyticum DSM 7109 RepID=B1VE82_CORU7  E=5e-07 s/c=0.21 id=37% cov=81%
-LRLLFQDANLLVVDKPP----FMATLPRGQHIVETALVRArrQFGiPELSPAHRLDRLTRGVLMFTVRPEVRGPYQRLFDERVPEKTYEAVTlpadeapfppiprfRGWqewpaptpeqpwllrhhmVKERGRLATYLVEPEAPAIDATAPTDSGaaaaspshdmflaPPNALTKVVGVRSERraLAIAGGPTPRERRVLVwELVPETGKTHQLRVALRTLGLPILNDPLYEELSDEAlrdptaalpsppfAGEEDFG-RPMELTAQRLRFHDPLTGE---------------------------------------------
>UniRef50_UPI0001BC98D7(117-324:324) RNA pseudouridine synthase family protein n=1 Tax=Pseudomonas syringae pv. tabaci ATCC 11528 RepID=UPI0001BC98D7  E=2e-05 s/c=0.25 id=29% cov=80%
---ILYADEHLVVADKPHFLPVTPAG-EYVEQTLLRRLIHRLGNPDLVPLHRIDRHTAGLVLFSANRQTRSAYQALFPTRQIDKFYEAIAPAL----PGLEFPRLHESRLVeGEPFFRMQEGAGASNTR------TQIEVLERQDQLWRYGLY---PVTGKKHQLRVHMAALGAGICNDPFYPDVVKNPVDDYQNPLKLL---AKGLRFIDPLNGKQRQFESLLELDW---------------------------------
>UniRef50_B8LRV2(63-357:358) Putative uncharacterized protein n=1 Tax=Picea sitchensis RepID=B8LRV2_PICSI  E=0.0002 s/c=0.16 id=33% cov=85%
--EFIYEDEWMIAVNKPSGVYCEHVLSSIPEllasSPSSAGAANDVNPLELHLANRLDRDTSGVMVITKLHKIAGQLVKAFTDRKVRKTYLALCIGpapkWnniyiesghgrskfgawrvysrtdvgrilpggtVVREMATHLKVLavnanhrmhrDSVDKaqnssqgIAfdlkeDRFATvGDNGSTDSIE--KVVVTEQNSKAPGQdrdivsSPNIRKNdevLIRASPLSGRTHQIRLHCQYMGLPIRGDVKYEGphIWKGITYANH------ALHAESLCFEHPVTNNMVKFHAPLPQWVMEA------------------------------
>UniRef50_B8CQ92(27-261:278) Pseudouridine synthase n=1 Tax=Shewanella piezotolerans WP3 RepID=B8CQ92_SHEPW  E=1e-82 s/c=1.31 id=53% cov=91%
-IEILFEDDDVVAIHKPAGLLVHRSYLARRERFFAMQLTRDKVGCHVFPVHRLDRPTSGILLFAKSSEMANALCEQFAAHSIDKEYLAIVRGNMHEAATLDYALKEELDDVADKDVDPNKAAQDAITSYKPLLNSEIPYASGRYATSRYALVHLSPHTGRKHQLRRHMAHLRHPILGDTTHGDGKQNKFFREHFGINRLWLIAKKLSFNHPRTGERVAVETELEQEWITLFDELGW------------------------
>UniRef50_C6XFD0(90-338:340) Pseudouridine synthase n=1 Tax=Candidatus Liberibacter asiaticus str. psy62 RepID=C6XFD0_LIBAP  E=2e-79 s/c=1.20 id=27% cov=88%
-LDILYEDDDIIVINKPAGLVVHPAPGNWTGTLVnaLLYHCHNNLSsingvKRPGIVHRLDKDTTGVMVVAKNDLAHQKLSEQFVDHgkstRLKRAYYAMVWGIPlPDSGIINAPLGRCKSNRLRRAVKgiDDKTADSAITHYQTIE------IYNKNSNFAVSLLKCHLETGRTHQIRVHMAHKGNPLIGDPLYGKGFKtkanivnNNAKSAILSLARQALHAHSLSFSHPRNNQDMDFQVPIPEDMLTVIRKLN-------------------------
>UniRef50_Q15QZ8(3-247:252) Pseudouridine synthase n=5 Tax=Bacteria RepID=Q15QZ8_PSEA6   E=6e-79 s/c=1.21 id=52% cov=95%
-LTILYQDECLVAIHKPAGLLVHRSMIDRHETQFAMQMLRDQIGQHVFPVHRLDRPTSGVLVFALSADIARLLGEQFAGNTIAKTYFAIVRGHVKEAGLIDYALKEKLDKIADKRAKQDKDAQEAQTEYVPLQQFELPFAVSRYPSARYTLVRLHPKTGRKHQLRRHMCHINHPIVGDTTHGDGKHNKFMRDQFSFNGLALTCQQMCMTHPVSNEKLAIVNDFDQRMSTLMVQWGWE--LPSLDRLDL------------
>UniRef50_Q39Z12(1-242:270) Pseudouridine synthase n=3 Tax=Proteobacteria RepID=Q39Z12_GEOMG   E=6e-79 s/c=1.22 id=51% cov=93%
-MEILYRDEHLVAVHKPLGLLVHRSPIDRHETRFALQEVRDLLGRRVYPVHRLDKPTSGVLLFALDPAFARGLVGAFASGSVTKTYLAVVRGTMPEEGVIDHPLAEEPDRFEQGRGNAgERAPQSAVTGYRRLADVELPVAVGRYPTSRYSLVSLSPRTGRRHQLRRHLKHLFHPIVGDTKYGEGRHNRFFREELLTVRMLLHAVELTVPHPATGAPLTVCAPVEGAFAALLARFGWLSAVPS------------------
>UniRef50_C4FYR8(99-325:326) Pseudouridine synthase n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4FYR8_ABIDE  E=7e-77 s/c=1.27 id=33% cov=85%
-LDILYEDEDVILINKPKGMVVHPAAGHYTGTLVnaLMYHCRDNLSGingelRPGIVHRIDMDTTGVIIACKNDVSHRIIAEQLKEHSIKRKYQAIVYGVFKdEEGRIEGSIGRSKTDRKKMAVIPD--GKPAVTHYRVIRNYTSPN------GNNFAHIECELETGRTHQIRVHMTSIGHPLLGDEIYG------AAKNPFKLDGQALHAEMLGFVHPRTGEYMEFHAPLPEYFSKLLTKL--------------------------
>UniRef50_C9KPZ8(80-305:308) Pseudouridine synthase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KPZ8_9FIRM  E=1e-76 s/c=1.27 id=35% cov=84%
-LDILYEDSDIIVINKARGMVVHPATGIYTGTLVnaLLYHCKDLSGingeIRPGIVHRLDKDTSGVMVAAKNDAAHLDLAEQIRTKAAHRIYRAIVCGNIREEAGVIKGDIGRHPTDRKKMAIVHEHGKPAVTHFRVLERF-----------GAYTLVECRLETGRTHQIRVHMASIGHPVLGDPKYGPRK-----ACPFAIKGQALHSLQLTLTHPRTREVMTFTAPLPEDMEKILKAL--------------------------
>UniRef50_B8CWM0(82-303:308) Pseudouridine synthase n=1 Tax=Halothermothrix orenii H 168 RepID=B8CWM0_HALOH  E=1e-74 s/c=1.27 id=31% cov=82%
-LDIIYEDKDILVLNKNAGLVVHPAPGNHENTLVnALIAYCDNLSTisgvnRPGIVHRLDKDTSGVMVIAKNDISHRKLVEQFKQRKTKKYYRTLLKGELPyKEGKIDAPIGRDP-HDRKKMAVTRKNSKKAVTYFKVLEFFR-----------DHSYVEVELKTGRTHQIRVHFSYMGFPVVGDSIYGKKR------NRLQATRQLLHAYRLGFYHPRNDKWVEYKASLPDDFKKALD----------------------------
>UniRef50_Q3A0C2(83-316:326) Pseudouridine synthase n=13 Tax=Bacteria RepID=Q3A0C2_PELCD   E=3e-73 s/c=1.18 id=32% cov=85%
---ILYEDRHLIVIDKPPGMVVHPAPGHYQGTLVnaLLHHCQDLSGIggelRPGIVHRLDKDTSGVMVATKTDSAHQSLAAQFKAHSITRRYIALIHGVLTgDRGSIDRPIGRHPTH-RKKMSTTCRTGRHAVTHWRVLR---------RFDDDRLTLVELALETGRTHQIRVHFSEQQHPLLGDPVYGGSGRLKTINDPQLLKrakalgRQALHARLLGFQHPETGKYLEFSSPLPEDLRSVIDYL--------------------------
>UniRef50_D1RB31(87-317:319) Pseudouridine synthase n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1RB31_9CHLA  E=5e-73 s/c=1.19 id=32% cov=86%
-LNILYEDEHLLIINKPVGMVVHPAPGNWTGTFVNALLYHcgyslsdaSVDSIRPGIVHRLDKETSGVLVAAKTLSVQQKLMELFAARQVYKEYWAICLGNP-GNCELNWPIGRHPIHRKQMTVRED--GKEALTFCETLEV-----------GNEICLAKLILSTGRTHQIRVHLKHKGHPILGDSIYGSKQVN----MRYRAERQMLHARKLAFIHPITQQKIEVEAPLPADMEECLRK---KAMLERTEK---------------
>UniRef50_B1I3F8(81-302:309) Pseudouridine synthase n=2 Tax=Bacteria RepID=B1I3F8_DESAP   E=5e-73 s/c=1.24 id=35% cov=83%
-LEVCFEDPDVLVVNKPRGLVVHPAVGHYSGTLVnaLLHHCRDLSGIngilRPGIVHRLDRDTSGLLMVAKNDAAHLALAGQLKDRAVLRRYTALVHGRPRREtGTVDAPIGRHP-RDRQRMAVTPRSGRAARTHYRVVRRFD-----------KFSLLELTLDTGRTHQIRVHMAHVGHPLVGDLKYGHARP------ELGLEGQFLHAGTLGFRHPRTGEVLVFEAPLPSELAAVLERL--------------------------
>UniRef50_D0RPR1(81-320:325) Pseudouridine synthase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RPR1_9RICK  E=6e-72 s/c=1.14 id=27% cov=85%
-LNIIFEDQDIIIIDKPIGMVVHPGAGNYEDTMVngLLYHCKNNLSgmngeDRPGIVHRIDKDTSGLLVVAKNDQAHAFIAKQFEEHSIKRSYLVFVYGILRPlHGKIETLIGRNKTN-RQKMSADVIRGKDAITNYETLEVFKGNKIP------DISLVKCILETGRTHQIRVHMSHKGNPILGDQTYGKKIKKIRGIDQEfeeilkSLKRQALHAHTLGFIHPTTNEEVFFASELPDDL---------------------------------
>UniRef50_Q2LWV4(85-329:333) Pseudouridine synthase n=1 Tax=Syntrophus aciditrophicus SB RepID=Q2LWV4_SYNAS  E=8e-72 s/c=1.11 id=31% cov=90%
-LSILYEDHDLLVLDKPAGLVVHPAAGHVSGTLVnaLLFHCRDLAGIggvmRPGIVHRLDKDTSGLLVVAKTDAAHQGLALQFKKHQVGKTYQALVYGDPREKtGQIDLPVGRHPV-ERKKMSTKSRRGKEAATRWRIAERFGVA-----------TLLNVDIVTGRTHQIRVHLAAIGHPVVGDAVYGSSKRATTLTDPavkgrlKEMSRQALHAARLSFTHPVTHKILEFHAPLPADMEDLCAFLR-KHCCPDSQLV--------------
>UniRef50_C0BNA6(132-372:379) Pseudouridine synthase n=7 Tax=Bacteroidetes RepID=C0BNA6_9BACT   E=1e-71 s/c=1.12 id=27% cov=86%
-LDVVYEDSDLMVVNKPPGMVVHPGHGNYSGTLINALLFHVKdlplnADERPGLVHRIDKDTSGLLVVAKTAKAMTHLAKQFFDKTSEREYVAIVWGNVEEEqGTVRGHIGRHPKNRLQMAVFPDGDqGKEAVTHYKVMERLGY-----------VTLVSCVLETGRTHQIRAHMKHIGHTLFNDERYGGEKILKGTTftkykqfvdnAFKALPRQALHAKTLGFVHPSSGELMRFNTPIPEDMVLCIEK--WR-----------------------
>UniRef50_D1VS73(75-293:295) Pseudouridine synthase n=1 Tax=Peptoniphilus lacrimalis 315-B RepID=D1VS73_9FIRM  E=1e-71 s/c=1.24 id=27% cov=82%
-FNVIYEDEYIAVISKPQDLVVHIGAGNSSGTLVngLLYKFKNQLSDldplRPGIVHRLDKNTSGLMIIAKNNQAHINLVDQFKNSQIKKYYLAIVHGKTPESGIIAEPIGRNPND-RKKMAVVYKNSKQAITKYKKLKEF-----------QEYSLLNINLLTGRTHQIRVHMAYIGYPVLGDIIYGR-------KNSLKIDKQMLHSYKLIFNHPITNQKMEFTDEFPIRFKKFIDK---------------------------
>UniRef50_A6C0W7(93-339:342) Pseudouridine synthase n=1 Tax=Planctomyces maris DSM 8797 RepID=A6C0W7_9PLAN  E=2e-71 s/c=1.10 id=30% cov=85%
-IDIVYEDDWIAIINKPSDMIVHPGKGNYAGTLAgALQYHFDQLSDvagqyRPGIVHRLDRNTSGIMVVAKDNQVHAKLSAQFEKRDVQKEYRAIVWGRMEfDTDYIDTFMCVHP-RAREKMIVCDEGGnaRNAFTYYEVIERYQA-----------FTYVRLKPRTGRTHQLRVHMQHIGHSIVADRVYGGHKSLKMKSlgiqaeadaaeleSDVLIERQALHAYCLEFFHPQSGKPMKFEAPLPEDMQNTLAAL--------------------------
>UniRef50_Q4FN11(82-321:326) Pseudouridine synthase n=4 Tax=Bacteria RepID=Q4FN11_PELUB   E=2e-69 s/c=1.10 id=29% cov=85%
-LQIVYEDDDLLIINKPAGIIMHPGAGNYDETIVnaLMHYNKDSLSTigdelRPGIVHRIDKDTSGLIVIAKNNETHENLSHQFSEHTITRVYQLLIWGKLrPSSGKIDTFITR-SSKNRQMMEVSNSKGKRAITNYKTIEIFEND------KTPTLSLVECRLETGRTHQIRVHMTHMGNSIMGD---GKYKKKYKKLKNidtnlenliYKLDRQFLHAQTLGFIHPRTNEEMVFTSILPQELENIL-----------------------------
>UniRef50_C1ZGS9(91-337:345) Pseudouridine synthase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZGS9_PLALI  E=7e-69 s/c=1.06 id=31% cov=89%
-LDILYDDEYLCVINKTANMIVHPGRGNYRGTLagalqFHFDSLSDVAGQyRAGIVHRLDRDTSGVLVVAKDNTVHQHLSRQFEERSVEKEYHAIVWGEMQFDADYVETYVRVSFRNRERMMVCPPGdnARQAATFYEVQQRFR-----------GFTYVKLQPQTGRTHQLRVHMHHLGHPIIADRLYEGKtcvklsdilPETPEEADETLIDRQALHARRLAFNHPVTKKRMVFEAPLPADFQKTLDTLKTHAIKPK------------------
>UniRef50_B9YI75(99-327:329) Pseudouridine synthase, RluA family n=1 Tax='Nostoc azollae' 0708 RepID=B9YI75_ANAAZ  E=1e-68 s/c=1.14 id=31% cov=85%
-LDILYEDEQLLILNKPAGLVVHPAPGHLDGTLVnaLLAHCANLPGiggvQRPGIVHRLDKDTTGAIAIAKTDIAYQHLQAQLQAKTARREYLGVVYGVPKtESGIINLPISRHPqDRKKMAIVPTEQGGRTAITHWQI-----------RERLSNYTLIHFQLETGRTHQIRVHSAKIGHPIVGDSVYGAGR-----SVGVNLAGHALHAWQLKLQHPISGDWIQVTASPPQTFTTLLEVLRRRS----------------------
>UniRef50_B0VJ94(89-328:351) Pseudouridine synthase n=1 Tax=Candidatus Cloacamonas acidaminovorans RepID=B0VJ94_9BACT  E=2e-68 s/c=1.09 id=31% cov=85%
-LDVVYEDEYLAIINKKAGMIVHPGFGNPEGTLVNAILYRFGENlssgkefNRPGIVHRLDRGTSGLIIIAKNDLTHAKLSDMFARREIKKTYFAITTGIPePEKGEIETYLARSNKNP--RTICVTNEGRYALTHYKTIKTWHY-----------FALVEINPATGRMHQIRVHFAHIRYPILGDLLYNSRRYVQSLVPQnmkkkvtellvNHLRRQALHSWKLEFFHPITGYPISVSAPIPDDIQYTLNWL--------------------------
>UniRef50_C7LP91(9-237:245) Pseudouridine synthase n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LP91_DESBD  E=3e-68 s/c=1.14 id=42% cov=88%
-IPVLHRDEHLIAVHKPAGLLVHRNA-HAGREPFLLQILRDQLGQRLYPVHRLDRPTSGLMIMALSPQAAHALALQFASQEVHKTYLAVTRGFVPPQGLIDDALK-----------SESGSLQEARTEFTRLATAEIPHPVGPNPTARYSMVRVRPRTGRTHQIRRHFAHIRHPLIGDVLRGDGRQNRFFRDHFGLHRLLLASVELTFRHPEDTSPMTLTCPPARELLDLFGQLGWNAAIDA------------------
>UniRef50_D2R7T3(115-350:355) Pseudouridine synthase, RluA family n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R7T3_9PLAN  E=4e-68 s/c=1.10 id=35% cov=86%
-LDILFEDEHLIAVNKPPGMVVHPARGHWSGTLTSALAFHFQqlstvgGQHRPGIVHRLDRDTSGVIIVAKTDPVHFSLAAQFADRTTAKEYFAITAGVPDRDRdVVSQPIGIHPFHREKMAIRPgHSTSRDAETMFHVLERF-----------AQHAAVECLPKTGRTHQIRVHLAHVRTPVLCDKLYGGRAEItqgelvRDGSTEVVLNRQALHARKLSINHPKTGERLTIEAPLPADLQRVLDLL--------------------------
>UniRef50_A5IBH6(87-319:321) Pseudouridine synthase n=6 Tax=Legionella RepID=A5IBH6_LEGPC   E=2e-67 s/c=1.11 id=29% cov=85%
-IQIIYEDSEVIVVNKPAGLVVHPGAGNKEHTLVnalLHHCPELQLLPRAGIIHRLDKDTTGLLIVAKNLISHTSLIRQMQNREIKRHYLTLVHGYVISGGTIDTGFGRHP-KNRLKMAVTDFG-RQAVTHYNINKHYK-----------DFTLLNVSLMTGRTHQIRVHMNYINHPVVGDQLYGGRMKFPPNADEAILsvlkqfKRQALHACSISFCHPVKNTEITLNALLPDDFELLLNTL--------------------------
>UniRef50_C7H7W3(80-308:314) Ribosomal large subunit pseudouridine synthase D n=2 Tax=Faecalibacterium prausnitzii RepID=C7H7W3_9FIRM  E=5e-67 s/c=1.12 id=30% cov=85%
-LDIIYEDAHLLVVNKPKGMVVHPAPGNPDGTLVNALLWHCKGSlsgiggeIRPGIVHRVDKDTSGLLVVAKDDATHIGLSQQMAVHSVERAYNTIVYGGFAqDEGFVESNLGRSKTDRKKMAVYPASEPhtKYAYTGYKVLERL-----------GEFTMLECRLKTGRTHQIRVHMASIHHPVAGDPVYGPHNCITS------LHGQCLHAKTLGFIHPITGEHLRFDSELPDYFTRFLTTLRQR-----------------------
>UniRef50_C8WW59(91-307:314) Pseudouridine synthase n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WW59_ALIAD  E=7e-67 s/c=1.18 id=30% cov=80%
---VAYEDDDVIVVDKPRGVVVHPGAGHMRGTLVNGLLARGtplctlAGALRPGVVHRIDKDTSGLVVFAKSDRAYRALVEAFRAHDVEREYVAIAHGRMPhREGTIDMPIARDPADRQRMAVR--QGGKRAVTHFEVLESF-----------AKYSYLRLRLETGRTHQIRVHLAAIGHPIAGDPVYGPRH-------TLPIDGQALHARTLGFTHP-DGRRLRFESAVPSDMARLLD----------------------------
>UniRef50_Q03WF6(90-300:312) Pseudouridine synthase n=9 Tax=Firmicutes RepID=Q03WF6_LEUMM   E=8e-67 s/c=1.21 id=33% cov=79%
------------VVNKPQGMVVHPAAGHSSGTLVNALLHHSPLSTingefRPGIVHRIDRDTSGLLMVAKNDKAHRSLSEQLKSHKNQRVYYALVRGEFTEDsGTIEAPIGRH--KIDRKKQAVIEGGREAVTHFRVLKRY-----------VGYTLLKVSLETGRTHQIRVHMSYIGHPVVGDPVYG----TAQKLDGTQLNGQLLHAKTLTLEQPTTGDELSFDSPLPDYFQFALSTL--------------------------
>UniRef50_A5IZB6(76-291:305) Pseudouridine synthase n=4 Tax=Mycoplasma RepID=A5IZB6_MYCAP   E=1e-66 s/c=1.18 id=31% cov=80%
-LDIRYEDEYLLILNKPSGLVVHPAPGHLNDTLVnaLMYHFKNNLSDangllRLGIVHRIDKDTSGLLIIAKDNETHNELAKMLKNHQIKRTYLAICEGILPNKTTkINLPIQRDTKN--RKLMSIHKDGKSSVTYVHMLKSFYI-------DNKPYSLVKCELETGRTHQIRVHLAYIKHPVYGDSIYGKSVDEFN---------QRLHAYKLSFMHPVINKLIEVYSDIPKEF---------------------------------
>UniRef50_C1CWT3(77-313:321) Pseudouridine synthase n=1 Tax=Deinococcus deserti VCD115 RepID=C1CWT3_DEIDV  E=2e-66 s/c=1.07 id=34% cov=87%
-LDVIYEDDYLIAVNKPPGMVTHPAPGVLSGTLVNALLGRmplpeqpdydSEAGYRPGIVHRLDKDTSGVIVVAKTVGAHARLAAAFKDRETRKTYLAIAAGQWRADGpaRVEAPIGRHPVQ-RQRMTVGGANPREAQTLFTPLAA--HPDGHGRT----LALVRAQPRTGRTHQIRVHLAHLGSPILGDAVYGRSSET--------MLRHALHAHFLSVPHPGTGRLLHLHAPAPDDMLNAWIALG--GAMPSD-----------------
>UniRef50_C5J6Q2(82-298:306) Pseudouridine synthase n=1 Tax=Mycoplasma conjunctivae HRC/581 RepID=C5J6Q2_MYCCR  E=2e-66 s/c=1.17 id=30% cov=81%
-FEIVYQDNDIIVINKPKNLVVHPGNGNWDKTLVNGLLhefatnLSDVNGEiRPGIVHRLDKDTSGLLLVAKNNQAHKYLAKQLENHEIERKYIAIVVGKIPHtKMRINLPIGRDNQNRTKK-VVSSFNSKNAITNVELINTF-------VYKNEHFSIVKCILETGRTHQIRVHLSHIGYPIYGDPVYGKKIDDL---------GQRLHAYEITFKH-LDGRLMNFKTEMPDEFK--------------------------------
>UniRef50_O67638(82-311:316) Uncharacterized RNA pseudouridine synthase aq_1758 n=3 Tax=Aquificaceae RepID=Y1758_AQUAE  E=2e-66 s/c=1.10 id=29% cov=85%
-INIIYEDEDIAVVEKPCGLVVHPSPGYTSGTLVnaLLYHIKDLSSiggvERPGIVHRLDKETAGVMVIAKNNTAHRNLVRQFQERKTEKFYKVLVKGLVKKDyGAIDTPIARHP--VDRKRFWVRKEGKEALTEYWVLK---------RYEKYEITLLKVKIHTGRTHQIRVHFASIGHPVLGDRTYG-FKSSSVPKELLSLMGecNMLIAYHLGFYHPTKGEWMVFEIEEPETFKSVYSWL--------------------------
>UniRef50_A7H6D3(87-332:339) Pseudouridine synthase n=6 Tax=Cystobacterineae RepID=A7H6D3_ANADF   E=3e-66 s/c=1.03 id=34% cov=92%
---VLHEDADVLAVDKPAGLAAHPGTGISGATLVEMARAHlgtpadlPPTEFKPSPAHRLDRDTSGVVLVAKNRKTMVRLTELFTDGaDVKKTYLALVKGKMPREaGTIDLPLAEHEQTARSKAARGV-NLQEALTRWKVVSAMK-----------EASLLAVTIETGRTHQIRRHLEAVGHPVLGDRRYGDFPTNRAARQRWGLRRMFLHAWRLELPHPTTGAPLRLEAPLPGELLEALSRANLSS--PAGTASGRAAPRGA------
>UniRef50_A5ZUU7(81-293:293) Pseudouridine synthase n=1 Tax=Ruminococcus obeum ATCC 29174 RepID=A5ZUU7_9FIRM  E=4e-66 s/c=1.19 id=28% cov=81%
-IPVLYEDEDILVVNKPADMPVHPSLGNYTNTLangVAAYLETKGESCPFRCINRLDRDTSGALILAKNALSAAILSVQMRNRQISRTYLAVVEGIPRQSGTISAPISRAADSVIERRI-DFENGESAITHYQLLEV-----------KNNHSLLEIHLETGRTHQIRVHMGYIGHPLPADYLYNPVYDT--------FKRQPLHSLQLKFCHPITGTPMCLMAPVPEDMSNAF-----------------------------
>UniRef50_Q2S3B7(74-338:349) Pseudouridine synthase n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S3B7_SALRD  E=7e-66 s/c=0.95 id=30% cov=86%
-LDVVHEGDDLLVVNKPAGMVVHPAPGHRSGTLVHALLHHVDGGEvaadderdevsedevglslvnalpqspdhpvvRPGIVHRLDKGTSGLLVVAKRGRAHQPLAEQFKAHTVDRRYRAIVWGRFaPSDGTIEGAIGRDPHHRQRMAVVPEDEGKWARTHYETVET-----------HAHTSVVEFELETGRTHQIRVHARAQGHPLLGDPKYGGQRVRYGTQSGTRrtfydqlfetLPHPALHAYRLGFDHPTTEERLRFEADPPPAWRRVLREL--------------------------
>UniRef50_Q5PAD0(82-326:327) Pseudouridine synthase n=5 Tax=Anaplasma RepID=Q5PAD0_ANAMM   E=2e-65 s/c=1.02 id=26% cov=90%
-LKVVYEDHDVIVIDKDPYIAVHPGNGIEHHTITNALLARFGAGlqsvgssSRPGIVHRLDKDTSGLMVAAKTENAYYRLSEELANQGFKKEYLAVAWGIPCPKRGVIHTNIRVKRSDITMMEAANSGGKPAKTEYEV----------EQELGEVASLIRCTLHTGRTHQIRVHMSHIGHSIVGDQKYGKncKKCMRSGvpPDVKNFRRQALHASLLGFRHPSTGKYIEFTSKPADDIQQLISALERAGNLQARNR---------------
>UniRef50_C0GNZ6(83-315:535) Pseudouridine synthase, RluA family n=1 Tax=Desulfonatronospira thiodismutans ASO3-1 RepID=C0GNZ6_9DELT  E=2e-65 s/c=1.08 id=33% cov=85%
-LDIVYMDREMVVLNKPAGLSVHPSSSDPAPTLVHYLLYACPGlrlmtdRQRPGIVHRLDKDTTGLMVAALNQEAKEDLAGQFAGRRVHKTYLALVCGALKqDEGIINVPLARDQQSRAR--VAPSREGRSARTAYKVLK---------RDPSGLWSLVQVQIFTGRTHQIRVHFSHLNHPVLGDRIYGGTDWDRFGWKKRFLsrlaKRQLLHSSCLGIMHPVSRQWLEFISRPPRDFIRTL-----------------------------
>UniRef50_B1ZYX0(80-305:311) Pseudouridine synthase n=4 Tax=Verrucomicrobia RepID=B1ZYX0_OPITP   E=3e-65 s/c=1.11 id=30% cov=84%
-LTVLFEDKHMLAVNKAAGMVVHPGVATSEDTLVHALLAHCAGSlsgiggvERPGIVHRLDKETTGVIVVAKTDAAHRALADQFATRTLKKEYVALVAGVPRlLSGSIDRAIARHP--VHRHRMTVGEGGRPARTDWELVEAFGDIG----------ALVRCRIFTGRTHQIRVHLKSLGHPILGDALYGWKPEPRLATQP---ARVMLHAEHLVLTHPISGKELDLRAPLPKDFVAMIKEL--------------------------
>UniRef50_Q01Q94(77-296:296) Pseudouridine synthase n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q01Q94_SOLUE  E=1e-64 s/c=1.13 id=35% cov=81%
-LRILYEDADVVAIDKPAGMVVHAGAGVHSGTLVNALLHRFatlsgvGGPLRPGIVHRLDRFTSGVLLVAKNDAAHQKLAAQFSGREIEKVYLALVHGTVkPETGRIERPIARDPVHRARMTARLAEG-RAAWSEYRVLRRF-----------PDFTLLEVRIGTGRTHQIRVHLASIRHPVVGDTLYGAPAQ-------PLLGRYFLHAHRIRFHLP-SGREMLIESPLPPDLEAWL-----------------------------
>UniRef50_P59838(86-319:321) Ribosomal large subunit pseudouridine synthase D n=3 Tax=Gammaproteobacteria RepID=RLUD_BLOFL  E=2e-64 s/c=1.06 id=28% cov=84%
-LNIIYEDNDILVINKASNMVVHPGIGHYQGTVLNALLYRYpsilKISKQAGIVQRLDKDTTGLMIIAKTVSAYDNLLRSFKLRKVVKEYDAIVYGKFTSNaGVVNQPMRRHFAK--RTFMSVHYTGKSAVTYYSVVEEFKA-----------HSRVRINLKTGRTHQIRVHMAYINHPLVGDQKYkGNFSVFDIKKMSdelnnylLDFNRQALHACTLQLLHPITQVQMKWNAPLPQDILQLIA----------------------------
>UniRef50_B4U613(79-306:308) Pseudouridine synthase, RluA family n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U613_HYDS0  E=6e-64 s/c=1.08 id=26% cov=85%
-IDILYEDNDLAVVVKPSGMPSHTGPGHDENTLVNALLAKFgdlsviGGVERPGIVHRLDRYTHGLMVIAKNDVSHQKLSLMFKNKEVDKHYKAIVYGISRfKEQTIETFIRRHPTNRLKFEV--ANEGKLAITKYSL-----------EKPLKNASLLDIKIYTGRTHQIRVHMSYIGHPIVGDTLYGYKHSYFDKTlEHMIGKRFLLVAYKLSFLHPKSQKPMEFEIDMPDYFKNVLKYL--------------------------
>UniRef50_C6LL16(85-296:313) Pseudouridine synthase n=3 Tax=Clostridiales RepID=C6LL16_9FIRM   E=1e-63 s/c=1.16 id=31% cov=78%
-LDIVYEDEDLLVIDKPADMPVHPSIHNFDNTLAngLAYYYESRGEAFVYrCITRLDRDTTGLLLVAKNMLSGAFLAEMGKRREIHREYLAIVTGKTEAEGTVDAPIARVEGSVLERCVDFQRGER-AVTHYRTLEYRD-----------GYSLVRLKLETGRTHQIRVHMKYIGHPLTGDFLY--------NPDYRLMDHQALHSHYLAFRHPITGERMEFTSQPP------------------------------------
>UniRef50_Q89AD9(85-314:317) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Buchnera aphidicola (Baizongia pistaciae) RepID=RLUD_BUCBP  E=1e-63 s/c=1.07 id=24% cov=85%
-LNVIYEDDDILVINKQDNFVVHPGAGNTSGTLLNALLHRDStffNIPRAGIVHRLDKDTTGLMVIAKNNLSYMALIDQIKCKKVIREYQAIVYGKVISGGTIVKSIIRNP--IKRTTMIVNKCGKRAITHYRILKRF-----------THHTHLKIILETGRTHQIRTHMLYINFPLVGDKTYGNKFKFYKNISLTLLeqvkkfPRQALHASRLCLYHPVTKHLMEWNSTLPRDMLNLIALLN-------------------------
>UniRef50_Q2G4F0(104-326:436) Pseudouridine synthase n=12 Tax=Alphaproteobacteria RepID=Q2G4F0_NOVAD  E=6e-63 s/c=1.09 id=28% cov=85%
---VLEKDRAAIVLNKPPGLATQGGSGTHEHVDGLLDAYVNEGEARPRLVHRLDKDTSGVLLIARTPGSAAFFSKRFSCRSARKIYWALVVGVPdVKDGLIELPLAKQPGTGGEKMMVDESGqGQSARSRYRVISR----------AGNAAAWVELQPLTGRTHQLRVHMAAIGHPIVGDGKYGGQAAFLTGSIS---RKMHLHARRLRIEHPE-GDMIDVTAPLPAHFAASMASLGF------------------------
>UniRef50_Q1Q689(91-330:335) Similar to ribosomal large subunit pseudouridine synthase D n=1 Tax=Candidatus Kuenenia stuttgartiensis RepID=Q1Q689_9BACT  E=6e-63 s/c=1.01 id=29% cov=82%
-LNIIYEDDYLMLINKPYDMVVHPAGGHPSGTLVNAvtfycQNLSQINGPlKAGIVHRLDRDTSGVMLVIKSDAVHSHIAMQFEKRLVKKEYFAVVEGEVAfDSNEINMPIGRH-RVDRQKMAVRRDTGKNATSVYEVIERFR-----------GYTLVKIMPKTGRTHQIRVHMQAIGHPVVADEMYSKynacfrsdlLGKERAPDEGSIIERQALHAHRIEFFHPILNKQMAFQVDMAED----------------------------------
>UniRef50_Q0BUM2(125-365:366) Pseudouridine synthase n=12 Tax=Acetobacteraceae RepID=Q0BUM2_GRABC   E=1e-62 s/c=1.00 id=35% cov=90%
---ILYKDDHLIVLNKPSGLPSQGGPGITRHLDGLLDGLRFGRDDRPRLVHRLDRDTSGVIVIARSPGVAAKLAALFRTRETEKVYWAVVAGRPVPvEGRIDRPLLRQNDRNEPVVlaDRKDRDKVTAITDYRTLD----------HAARKLAWLELRPLTGRMHQLRVHCAAMDAPILGDERYGswrntDERGVRNTALVEGLsRRLHLHARRLSLPHPAGG-MLSVEADLSPHMAETFETLGF------------TAPKAREGRL--
>UniRef50_B0S119(77-295:307) Pseudouridine synthase n=2 Tax=Finegoldia magna RepID=B0S119_FINM2   E=2e-62 s/c=1.10 id=28% cov=82%
-LDVVYEDDYLAIINKDKDVIVHPTETIYSDTLVNYLMYNFKNLSDVdgdyrrGIVHRLDKDTTGLIIIAKDNDTHLKLKEIIKNHEIIKTYLCIVHGKIDESGTIKEYMTRNP-KDRKKMMVSDEG-KLSISQYERLDY-----------NDDYSLVKVQIKTGRTHQIRVHMNYIHHPILGDKLYGLKK------EKILFDSQVLHAYNLQFIHPQTHEKINVIGKLKPDFMTAIEK---------------------------
>UniRef50_B7GEZ0(96-303:315) Pseudouridine synthase n=7 Tax=Bacillaceae RepID=B7GEZ0_ANOFW   E=3e-62 s/c=1.15 id=33% cov=79%
-LHIVFEDDHVLVVNKRAHMDVHPTQPGQTNTLanaVAFHFQCEGIYSKVRHIHRLDRDTSGVILFAKHALAGAILDQYLAKRTIRRTYIALVHGYVKqKKGTIEAPIGRDRHHPTRR--RVSKTGDTAITHYERLQYDKQ---------KHVSLVRLTLDTGRTHQIRVHMSYIGHPLVGDTLYGGKPW---------IDRQALHAFSLSFLHPFTEELITCSA-LPDE----------------------------------
>UniRef50_Q0F3G2(88-313:325) Possible pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F3G2_9PROT  E=3e-61 s/c=1.05 id=30% cov=82%
-LDILFEDEHLIVLNKPAGIVVHPSHGHDHGTLVhaLLHHCKTLPGingvERPGIVHRLDKDTSGSLVIAKSEVVHQRLSEMFAEHNLNRQYIAWCRGVPSwRVKCIELPIGRHP-HQRQKMAVTDSG-RESITDAAV-----------EHIFGPFSQMRLTLHTGRTHQIRVHMAHENLPVLGDPVYarsyhpGREIPEPARHAIATLSRQALHAELLEFDHPISGEPMSFRAPLPEDL---------------------------------
>UniRef50_B8I750(79-297:299) Pseudouridine synthase, RluA family n=2 Tax=Clostridium RepID=B8I750_CLOCE  E=1e-60 s/c=1.07 id=29% cov=82%
-LDVIYEDECMLVLNKQSGIVVHPTSYHPDNTIangIVYYLKQKGVTKKVRPVSRLDRETSGIIIFAKNQFTQEMLIQQMHNNLFKKEYLGIVQGIPqNNEGTINLPIARKPGSIMLRHISEE--GAPSITHYKILKT---------FPSHNSALLSFKLETGRTHQIRVHCKAMGFPIYGDTLYSDN-------TNLFISRQALHSYRTEIIHPVTLKGVIFKAELPSDISGLLE----------------------------
>UniRef50_C8PW17(141-362:365) Pseudouridine synthase n=5 Tax=Moraxellaceae RepID=C8PW17_9GAMM   E=3e-60 s/c=1.05 id=31% cov=82%
---IVYEDEGLIVLNKPSGMAVHGGSGESFGVIEAMR--EATGKKYLELVHRIDKDTSGLLMIAKKRSTLKTLQEHLREKTLQKTYLCLVVGWIsSETQTIDKPLLKytlpatQEGKSGERRVKVDvksEDSKPSQTQINVLQKFELN-------GQKVSLIEAKPLTGRTHQIRVHLASIGHPLLGDDKYNPNVAKGDKM----VRRLCLHAYQLAIP-----EYETITAELPVDMQNLIE----------------------------
>UniRef50_C9KIU1(78-294:296) Pseudouridine synthase n=3 Tax=Veillonellaceae RepID=C9KIU1_9FIRM   E=2e-59 s/c=1.06 id=34% cov=82%
-LDIRYEDDYLLIVNKPAGQLVHPTTKEAHGTLgnAVLYWYKAHGEHHAYhPVHRLDRNTSGLVLIAKVPQVQYKLTPRHGEGKLfHREYLALIEGELtPPEGLIDAPIARALPSIILRKVSPD--GQTARTHYDTVQT-----------DGKLSLIHLVLDTGRTHQIRVHLAHLGHPLLGDDLYGG--------NLARIKRQALHAARLHFRHPMTGAEIDVQVPLPSDMAQIVSDF--------------------------
>UniRef50_A4FXG9(81-297:298) Pseudouridine synthase, RluA family n=5 Tax=Methanococcus RepID=A4FXG9_METM5  E=2e-59 s/c=1.06 id=26% cov=82%
LLCVIYEDDDLLIVDKPKNMVVHPTKNVLSGTLANAISNHQKINNqnyKIRFVNRLDMDTTGLLIIAKNSYSHQQLAKQMDEGILEKIYIVVVNGHLdSKEGVIEDSIDLNDDGIKREL---STFGKISKTKYKVIEEF-----------NNVSVLEIKLLTGRTHQIRVHLSSFGNNIIGDTLYGKTAD--------LIERQALHSHILRFIHPITKENMEIRSKLPDDMENLIKNL--------------------------
>UniRef50_C2L1H2(90-330:335) Pseudouridine synthase n=1 Tax=Oribacterium sinus F0268 RepID=C2L1H2_9FIRM  E=5e-59 s/c=0.95 id=28% cov=83%
-LDIVYEDRDILLLDKPARLPCHPSPGHFEKTLagaIVFYQMQNSSASSfvCHFIHRLDLDTSGLILLAKNRLAASVLNKDMKEGRIQRSYLAFCQGNPEfslgeiqgftrlEEKkkkefnyafAISAPIARVEEEKMLRTVNFQKG-QEALSYFNVL---------NYFPEKNYSLLQLQLATGRTHQIRVHLSYLSCPLLGDSLYGNGEES-VFSQNIGLSRQALHSYSISFTHPIRKEKMFFQRELPPDL---------------------------------
>UniRef50_UPI00016B2413(175-379:379) ribosomal large subunit pseudouridine synthase, RluD subfamily protein n=3 Tax=candidate division TM7 RepID=UPI00016B2413  E=5e-59 s/c=1.12 id=34% cov=77%
--ETIYEDNDIIVINKPAGMLTH-AKGAIAEEFTAADIVKPITNykadtNRPGIIHRLDRNTSGVLLMVKNSDAASKIQKQFSQRTVKKTYYAIVCGIPyQHKALIDLPIERNPSRP--STFRVGVNGKSAQTSYEVERSI---------IKKNISLIKLQPKTGRTHQLRVHMQYLNTPILGDLVYGGK----------PAERMFLHAESLEVTL-LSGERKVFKAPLP------------------------------------
>UniRef50_Q54N28(430-710:718) Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum RepID=Q54N28_DICDI  E=1e-58 s/c=0.81 id=31% cov=87%
---VLYKDEHIIVLNKPQGLSVQGGTGLNKHLDMMLSHLRFEKDENPKLVHRLDRNTSGILILGRSKLAASAMTkkfelklvkenkkdkddnnnnknnknnnkndskRLFREKEVfnnnknkdeenenyskgiKKTYWALLGSTPtPKEGRIRAPLKKVVVGGFEKVVPtltTGDGAKIAITEYKVLES----------SLTKHCFISLWPETGRTHQLRVHCASvLNTPIIGDPKYGDKESDSNLKDLLPYPsKLHLHARRIEFIHPFTNKKIDISAPLPRELVQNWKTMGFN-----------------------
>UniRef50_A4XKV9(77-286:292) Pseudouridine synthase n=1 Tax=Caldicellulosiruptor saccharolyticus DSM 8903 RepID=A4XKV9_CALS8  E=1e-58 s/c=1.09 id=29% cov=80%
-IDILFEDQFFLFVNKPSGIPSHPSKGHYFDTLAnNVEWYLNSQGVTSHIINRLDKDTSGIVVFAKNSYFHSIVSSEFEKRTIEKTYIAVVDGILtKKSGFIEKPISRSNDGIKREI---NEDGDYAITYYEVVDY-----------KNNYSILKLKPITGRTHQLRVHLASIGYPIVGDVLYGTGKNKNFP--------LLLHAYSMKFDFKLIERQYNITAPLPPYFSEFL-----------------------------
>UniRef50_A9GBV3(90-336:345) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GBV3_SORC5  E=1e-58 s/c=0.92 id=30% cov=87%
VIPVVYEDEHLLVIDKPAGLVVHPARGHASGTLVNGLLAlpgfalapadpRDPMGHvRPGIVHRLDRGTSGLLVVAKDEPTREALKDRFARHAIEREYAAIVAGEARDATYDTLHGRHPTDRLRftswirggaGAPGSHVAAPRRAVTHVRVIERL----------GDAATVVACSLETGRTHQIRVHLAERGrTPVLGDPLYGKPPKKPAVrAIAEELGRQALHARVLGFIHPATQKPVRWESALPADMRKALDQL--------------------------
>UniRef50_Q38VN9(78-296:306) Pseudouridine synthase n=1 Tax=Lactobacillus sakei subsp. sakei 23K RepID=Q38VN9_LACSS  E=2e-58 s/c=1.04 id=31% cov=82%
-LKIAYEDDHFLIVDKPAFVASLPAPNHPNNTManFVKQYLIDEQAESlaVHVVTRLDRDTSGLMMFTKHGFAHSLLDRQLQSKELQKTYIAIASGdmreDLPQHAWIDRPIKRSEEFYMRRVV--GEGGKRSLTEYWQAAH-----------GDGATLVKLKLLTGRTHQIRVHFASLGHSLIGDNLYGES--------NDLLPRQALHCRQLTFYHPFEERTITVKSPVPADFSAVLAQ---------------------------
>UniRef50_B9L8H5(77-288:311) Pseudouridine synthase n=1 Tax=Nautilia profundicola AmH RepID=B9L8H5_NAUPA  E=2e-58 s/c=1.08 id=28% cov=80%
-IPVLYEDEDVLVINKPPGIVVHPAPSVKEATLVDWLKTKNYrlstiaGEERFGIVHRIDKETSGALIIAKNNKAHEFLSAQLKDKTMGRYYIMLLNEPLKEAVCVDKPIARNPKNRLKMAYV--KNGREAKTLFVPVYEN---------------VAAAKLFTGRTHQIRVHLSTIGRYILGDTLYGKKEQK--------LPRVMLHAKELYFIHP-SGKKLSIIAPMFDDFKKNLPK---------------------------
>UniRef50_B0T2G2(54-275:286) Pseudouridine synthase n=6 Tax=Caulobacteraceae RepID=B0T2G2_CAUSK   E=5e-58 s/c=1.02 id=32% cov=83%
---VIHEDDSVFVLNKPAGLSSQGGRIQAHTLDDLLWALARRDRPRPRLIHRLDRDTSGVILTARTKPAATFLGKALMGKRFRKTYWAIVTpGAPePRGGQIDSPLRRESIGREAYMRVceaDHPDAETARSRYRTLAATE-----------GAALVELSPDTGRMHQLRVHMASIGRPIAGDSRYGGALMLGGA----PVPRLMLHAANLVFPHPEGGER-RISAPIPDDMRAILAKLG-------------------------
>UniRef50_C6J8T7(107-340:349) Putative uncharacterized protein n=1 Tax=Ruminococcus sp. 5_1_39BFAA RepID=C6J8T7_9FIRM  E=6e-58 s/c=0.97 id=32% cov=84%
-LNILYEDTDILAVDKPAGMVTHPTGMHYTDSLsnLVAGYFREKNEQvCVRPVGRLDQETSGIVVFAKNQVAASRLQSVKSPCKIHKQYLAAVSGTLPVDMpgvwhTLDLPLMQDPENHLKMKTAADlslhssalsGKIKTAVTHYHTL-----------FSSQDWSLITLKLDTGRTHQIRVHMASTGHPLLGDTLYHSDDKISSCA---SFSRAALHAWKVSFQHPFRDEMLLLEAPLPFDFRELVS----------------------------
>UniRef50_B0PDX0(81-288:292) Putative uncharacterized protein n=1 Tax=Anaerotruncus colihominis DSM 17241 RepID=B0PDX0_9FIRM  E=6e-58 s/c=1.09 id=28% cov=79%
-VEILYEDSDVIVYNKPAAMACHPVRGLRQGTLanvFARDCAANGESCACRLVGRLDRDTSGAVVIAKNARAAAVLT-----GHVEKQYIALVTGMPnPKHGVIDAPIGQPDRKNPRRMIV--ANGKPAVTEYETQIRCE-----------GYSVVHCVLRTGRTHQIRVHMASIGCPLLGDTLYGG--------ETERIERQALHCMQASFIHPVDKRLCIVHAPIPKDMQKLI-----------------------------
>UniRef50_A8Z5T0(101-333:337) Pseudouridine synthase n=3 Tax=Candidatus Sulcia muelleri RepID=A8Z5T0_SULMW  E=1e-57 s/c=0.97 id=22% cov=82%
-INIFYEDEYVIIINKQSGLVVHPGKGNESMTLINGLHFYFLKKKNIYnkipiLVHRIDKGTSGLILVAKDKNILEKIYKQFYINHIKRKYITLVWGYIKNNkGTIICNIGRSLKNRIYMNVFPNGIyGKFSITHYKVLERFKY-----------VTLLKCTLETGRTHQIRVHLKYIGHPILNDKDYGGNHTFKEKKNikklFINMKYQALHAYYIEYIHPIYRKKNYFICPIPD-----------------------------------
>UniRef50_B6WA53(74-297:299) Pseudouridine synthase n=2 Tax=Anaerococcus RepID=B6WA53_9FIRM   E=1e-57 s/c=1.00 id=24% cov=80%
-LKIVYENKDYAIIDKDENVIVHPAGSIVSGTLVNGLLYHFGYNnlshiggdDRPGIVHRLDKDTTGLMVIAKSNSSYKFLKNLFETRKIDKEYLAICNGIFkKKSGEIHTFMDRDPNNRRKMAVRNS--GRDAISKYEVLSE-----------NDGYSLVKIKILTGRTHQIRVHMTHINHPLLGDPVYGNVKH------KFNLDHQLLHCHKLGFTD-KDGVYREFEADVHEDFKK-------------------------------
>UniRef50_Q1AVY4(76-293:305) Pseudouridine synthase n=2 Tax=Rubrobacteridae RepID=Q1AVY4_RUBXD   E=1e-57 s/c=1.03 id=30% cov=82%
-VPILFEDEHIAVVDKPAGMVVHPGAGNRSGTLVNALLGRGIAGgedpERPGIVHRLDRDTSGLMVVAKGEPAYSRLVEMLAARRVRRVYRALVVGEgLPPSGTVDSPVGRDPENPALMAAGV---GRPAVTHFEVLGEA-----------AGHTMLRVRLETGRTHQIRVHLSAIGYPVYADPLYGRAVPGR---------RLWLHAERLSFEHPAEGRPLDFFSPVPEELRRAAAELDAR-----------------------
>UniRef50_B9KFV3(76-313:320) Pseudouridine synthase n=2 Tax=Campylobacter RepID=B9KFV3_CAMLR   E=1e-57 s/c=0.95 id=27% cov=88%
-IEILYEDDDVLVLNKAPNIVVHGASSVKEATLVdwLLHkgyTLSNLNGEHrAGLVHRLDKGTSGAIIIAKNNQAHQFLANQLLDKSMGRFYLALSELPLKNDKMSNeKAIMRCPNNRLKKITTNTKNPlaKNAKTDFINLLSAK-----------NCSLIAAKLYTGRTHQIRTHLADFNRYILGDELYGYKGKIKY-------NRVMLHAYLIYFIHPRTKELMFIKAPMFDDFYQILKENFTQGEIDEKTSLDY------------
>UniRef50_C0M8E2(92-301:301) Pseudouridine synthase n=3 Tax=Streptococcus equi RepID=C0M8E2_STRE4  E=5e-57 s/c=1.06 id=33% cov=81%
LVDCLYQDEHLIIVNKPEGMKTH---GNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRLLEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQAFDQT-----------CLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQK----------AERLMLHAHQLTLRHPLAQEMIRVTAP-SKSFKEGLQQLN-------------------------
>UniRef50_A6LIG6(90-299:304) Pseudouridine synthase n=5 Tax=Bacteroidales RepID=A6LIG6_PARD8   E=6e-57 s/c=1.06 id=34% cov=79%
LLRIVWEDDDLIVINKREGLLSV--STDRIKERTAYRILSDYLKEcdprnKIFVLHRLDRDTSGIMMFAKNQKVKEQLQSNWSEAITQRTYVAVIEGRPEKDTdLIVSNLVE--NKHMQVYVTQDGDGKEAITRYRLLQT-----------NNRYSLVELDLETGRKNQIRAQMQSIGHPIAGDSKYG--------AETNPAGRLMLHARRLCFIHPVTGEEMRFETRIPEKF---------------------------------
>UniRef50_B7GQ28(79-291:320) Pseudouridine synthase, RluA family n=21 Tax=Bifidobacteriaceae RepID=B7GQ28_BIFLI  E=9e-57 s/c=1.04 id=32% cov=80%
---VVYEDDDVIVVDKPVGVAAHASVGWTGPTVLgslrdrGVHIASYGAAGREGIVSRLDVGTSGLMLVCKSDLAYTEMRRQFAEHEVKKTYHALVQGGLKENkATIEAPIGR--AKVSDFRFCVTPAGKPAVTHWDVLERF----------GHEATLVSVNLETGRTHQIRVHFSSIGHPLCGDPMYG---ANPVLSEALGLDRQWLHAMKLEFRHPRTRVWTTVRSQYP------------------------------------
>UniRef50_D2QJH0(89-304:308) Pseudouridine synthase, RluA family n=3 Tax=Bacteria RepID=D2QJH0_9SPHI  E=1e-56 s/c=1.03 id=34% cov=80%
-LTILYEDQFLIVINKQAGLLSMATNKERDRTaygILSEYTKKENPKNKIFIIHRLDRETSGVMMFAKSEKVQRLMQESWNATTKERTYVALVEGIPePPQGTITSYLRESKALIVYSSQNPDTG-QLSITNYTVTKT-----------GNGYALLELELETGRKNQIRVHMQDIGHPVAGDEKYG--------AESDPIGRLGLHAEVLAFEHPITGVPMRFDAPIPKSFL--------------------------------
>UniRef50_Q8D220(86-310:314) Pseudouridine synthase n=1 Tax=Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis RepID=Q8D220_WIGBR  E=1e-56 s/c=0.99 id=22% cov=83%
----IYEDDDILVINKYKDVIVHPG-CDKHENTLLHDILFNYPDSknlyRAGIVHRLDKDTTGLMLIARNSFSQKKLIKLLKLRLINREYRAVLLGKIICDGTVSAPIIRNSKN--RTRMKVHISGKESITHYKIIKNF-----------NDFSYVKINLESGRTHQIRLHMSYINHPVLGDFVYGNKKNKYIKTLYksiFNISRHALHARKIKFIHPINNCLMVHKIDLPDDMKILLKNL--------------------------
>UniRef50_Q67N67(74-317:327) Pseudouridine synthase n=1 Tax=Symbiobacterium thermophilum RepID=Q67N67_SYMTH  E=1e-56 s/c=0.91 id=33% cov=83%
-IQVVYEDPWLLVVDKPAGMVVHPVRDYVSGTLanaVAHHLLRSGSDPVARPVQRIDRETSGLVLFAKDPAVAGLLARELERQKLERRYVAVvegavaadagtvdrpirrVWGHPVAREVAEGPRTPEQERLlaeaaaQGRALREDwtAAGQPAVTHWRVLRRW-----------PAATMLELRLETGRTHQIRVHMAYLGHPLLGDELYGGSRT--------LIQRQALHAATLAFVHPVTREPVRFTAPLPADLEDLVARL--------------------------
>UniRef50_C0F0M1(83-306:306) Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM 3353 RepID=C0F0M1_9FIRM  E=1e-56 s/c=0.99 id=33% cov=80%
-LHILYEDEDLIFVDKPAGIVSHPSKGHLSDSMINgVQAYFENEGREknersnIHLIGRLDKETSGILGIAKNSVTAERMIKQRQRGILIKEYYALVKGNPPEEGILEIPMeemrdARDGDKLKMKVGK-SENAKTAKTFFQVVKRFE-----------KFSLVSLVIETGRTHQIRFHMASIGCPLLGDSFYGDGPE-------LGISRTALHAQQLTFTHPFCEKVMRIESEMPKDL---------------------------------
>UniRef50_A9BJA7(88-296:303) Pseudouridine synthase n=1 Tax=Petrotoga mobilis SJ95 RepID=A9BJA7_PETMO  E=1e-56 s/c=1.06 id=28% cov=81%
-FDIIYEDKDLLVINKPAKVSVHPGSKEEMATIIEGVMHYSRGEFEPHLVHRLDKLTSGVMVVAKNKQTARELTQLIKSRETRKYYLTLLVGNLNK---------------KSGELVSTVYGKTAQLKFNLKKKFDLFGEL-------YSLVEIELYTGRKHQIRVQFADLGFPIAGDDNHGDKKQNKLLRKNYGLKRIFLHASKISFD--YNNKHYDFYAPLSEDLQTVLDKL--------------------------
>UniRef50_C3XLR7(92-325:353) Pseudouridine synthase n=2 Tax=Helicobacter RepID=C3XLR7_9HELI   E=2e-56 s/c=0.94 id=27% cov=85%
-IPIIYEDSDLLILNKPANLIVHR--IDENDTQFTLVDYLKQKGFalsnlgdsyRLGIVHRLDKNTSGAIVIAKNNATHAHLSMQIKSKQMGRYYLCIINQPLKNPQTVEIPIMRHPKQRLKYITTTNNvNAKTAKTAFFMIPTLldSNFLKTENPKKEIPTLIGAKLFTGRTHQIRVHLNSINRHILGDGFYG-YKGNYTG-------RILLHAHFLHLIHPKTQKLLEFHAPIPDDMQNFIK----------------------------
>UniRef50_B2IK20(90-337:350) Pseudouridine synthase n=2 Tax=Beijerinckiaceae RepID=B2IK20_BEII9   E=4e-56 s/c=0.89 id=32% cov=86%
---ILFEDRDLMVLNKPFGLAVQGGSGMTHHIDKMLASLPNERGDRPVLVHRLDRDTSGVLLVAKTRRMAAELGEIFRSRQARKIYWAVVEGVPkPAQGRISLYLAkgegmedKRGPHGRDAEARAglekmrvakhgEEDARHSVTYYAIVDKV----------PSRLAWLSMKPITGRTHQLRAHAEAIGHPIIGDPKYGlkpkddPRRNDPNRAIPEGVERkLHLLARRLILPHPRGG-ILDVTAPLPPHMQKTFDLFGF------------------------
>UniRef50_C8PQT2(9-243:246) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PQT2_9SPIO  E=7e-56 s/c=0.93 id=34% cov=84%
----IYADDDMVAVNKAAGLLVAADRWDAEAprLDLLIQKELPQIAPscnKLYAVHRIDKDTSGILLYALNAEAHRTLNTAFQNREIKKTYRLLIHGRVSEEQfTVDLPLRADGDALH-RTVVDKRRGKEAVTHFTVLETFR-----------QFSLLEACPVTGRTHQIRAHLAAAGYPIVCDSLYGSGKPvllselkqrwrGDVYTEQPLIGRLALHAYRLEGVHPRSGQPFAFTAEYAKDFKSTVHQL--------------------------
>UniRef50_D1W0M0(351-560:566) Pseudouridine synthase n=1 Tax=Prevotella timonensis CRIS 5C-B1 RepID=D1W0M0_9BACT  E=7e-56 s/c=1.04 id=38% cov=79%
-LHVVYEDDALIVVDKPAGILSVPG---RSQRPSVYSILRSQMPSSVELfsVHRLDMATSGLLILAKNSVVYRHLQRQFRTHHIQKEYIAILEGALSQrEGVVTLPL-RPDPFDRPRQVVDWEHGKKAVTSYRVLNVRHGK-----------TWVALFPETGRTHQLRMHCAHaegLNCPILGDPLYGHHA-----------NRLYLHATSITFEHPISGQLLTLHAQPPADFQDVF-----------------------------
>UniRef50_A9MGU8(84-270:318) Pseudouridine synthase n=1 Tax=Salmonella enterica subsp. arizonae serovar 62:z4,z23:-- RepID=A9MGU8_SALAR  E=7e-56 s/c=1.17 id=26% cov=71%
-LDIVYEDDDILVINKPRDLVVHPGAGNPDGTVLnALLHYYPPIAdvPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQLREITREYEAVAIGHMTAGGTVNEPISRHPTK--RTHMSVHPMGKPAVTHYRIMEHFRV-----------HTRLRLRLETGRTHQIRVHMAHITHPLVGDQVYGGRPRPPKAHRKRLFPR--------------------------------------------------------------
>UniRef50_UPI00016C4782(62-272:275) RNA pseudouridylate synthase n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C4782  E=9e-56 s/c=1.04 id=37% cov=80%
-LEIVHEDAHLVVIDKPSGLLTVATESEKLDTAFVRlsDYLRARNAGRPFVVHRLDRDTSGLLLFARSAEVRDQLQGNWEE--LTKTYLAVVEGRPEsSEGGVENYLTEGRDLRVRASPRPGPDGKRAASRYTV-----------RQTRGGYSLVEVEIETGRKHQIRVHLAGLGCPVAGDKMYG--------ATTDPVRRLGLHAWRLSFDHPFTLERLELEAPLPSALAR-------------------------------
>UniRef50_Q6Q916(79-308:311) Pseudouridine synthase n=4 Tax=Bacteria RepID=Q6Q916_9GAMM   E=1e-55 s/c=0.95 id=23% cov=83%
-IDVIYENDDYLIINKQPNLIMHPGAGCSSGTLanaLLHHYPELKNIARAGIVHRLDKDTSGVILVARNDKFRNYFVDLLQKREVTKLYSAIVVGTIIGSFKVTDPIGRDKKNRVKMSIRSD--GKESETFVKLKESL-----------GNYSLLDISIMTGRTHQIRVHLSSKKLPIIGDNTYNPAKNIAKGTSSKLIdiikqfPRQALHAYQLSFKDMHTDEFKTFNCDIPDDMK--------------------------------
>UniRef50_Q1QR55(15-291:292) Pseudouridine synthase n=4 Tax=Bradyrhizobiaceae RepID=Q1QR55_NITHX   E=2e-55 s/c=0.79 id=31% cov=90%
---VLHRDGLMLVIDKPAGIPVHRGPKGGANLEASFEALRFGLPRPPVLAHRLDRDTSGCLVLGRHRKATASLGLLFKHGKISKTYWAVVEGGPTEdEGTIDIPLGR-LNHERGWWQKPDPNGLPSVTRWKVLGRGIFTAASDRFSPSpcgvetsearpegagargnsdgiapdhppprareegiQLTWLALEPVTGRTHQLRVHCAAMRWPIAGDNIYGTQASLRRLRNeqyipQFGEPSLHLHAREIAIPLSKNKPPIVVTASAPVHLHARLKACGWNG----------------------
>UniRef50_Q0ANT2(91-315:330) Pseudouridine synthase n=2 Tax=Hyphomonadaceae RepID=Q0ANT2_MARMM   E=2e-55 s/c=0.96 id=32% cov=84%
---VIYQDDELIAFNKPAGLAVQGGSKTTRHLDGMLDAFGEGLD-RPRLVHRLDKDTSGILIVGKGPKATARLAKAFQSHKTRKTYWAIAIGVPKPkmgeiKGFMRKAAASGVDSERETMVaagHGDEGAQHALTRYVVIGE----------AGQKASWVALRPVTGRTHQLRVHLAAMGTAILGDKKY---TCHRPAPEDLG-RRLCLHARRLEIPRP-GGKPLVLTADLPPALKKIYDTLGF------------------------
>UniRef50_C7GZU4(108-331:331) Pseudouridine synthase n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7GZU4_9FIRM  E=3e-55 s/c=0.97 id=27% cov=80%
---ILYEDDYIIVVDKPAGLLTH-AKGDKSCECTLSDKILEYtegslangsGANRPGVVHRLDRGTCGVMVMAKTDTALKHLTEAFEKQEVSKEYEAIVYdNIVRDSGVITAKIERNKKNRLKMSAGDE--GREAHTEFKVIERF-----------GKFTYVSLVIKSGRTHQIRVHMNYIHHPVLGDMLYGKRK------DKFNLMWPMLRSKKIGFLHPITSEKMEFTAAMPYEFKRIL-----------------------------
>UniRef50_B2S2T6(90-331:331) Putative uncharacterized protein n=2 Tax=Treponema pallidum RepID=B2S2T6_TREPS  E=4e-55 s/c=0.90 id=28% cov=85%
-LSILFENEDIIAVNKAQGMIVHPGAGHWTGTLVqalsFYRVYRARFEDEFsrqfqkgfpdffstlrqGIVHRLDKDTSGVLLTSRNMHAHEALVRSFKKRQVRKVYLALLQGVPARGvGVIETTIVRDRRRRTRFVASEDfSKGKYARTRYKVMK-----------ICGACAFVQFLLDTGRTHQIRVHARYLGCPVVGDPLYGSRNICGIPTT------LMLHAYAVRFVLPRTKKRITLVAPIPLRFVRLIHRLSVR-----------------------
>UniRef50_B7BE87(337-542:551) Pseudouridine synthase n=8 Tax=Bacteroidales RepID=B7BE87_9PORP   E=4e-55 s/c=1.05 id=38% cov=77%
-LEIVYEDESLLVVNKPAGMLSVPG---KSDVDSVYQRVRRMYPgaTGPMVVHRLDMATSGLMLVAKTKEVHQNLQAQFKNRTVCKRYVAWLDGIVEEkEGHLELPLRPDPED-RPRQVVDVVHGKPAVTDYRVLRYGGCKGGLRTTP----TVVSFVPKTGRTHQLRVHSAHplgLNAPIVGDELYGKKA-----------DRLYLHAEYLGFTHPVSGVYMEVE----------------------------------------
>UniRef50_B0VCN8(10-211:212) Pseudouridine synthase n=16 Tax=Acinetobacter RepID=B0VCN8_ACIBY   E=1e-54 s/c=1.06 id=35% cov=78%
----IYRDDDFMVIHKPSDILSVPGKGDLHDSVLTRLVA---IEPRTLLIHRLDRDTSGILVFGLSKRGQSAIARQFQDRQTSKIYEALVAGHLEGEGTVDIPVVYDPSRPPLHIVDASHN-KPALTHWQAIEHFQI-------QGQPVTRVKLTPITGRSHQLRVHMQYLGHPIVGDTLY-------AAPEQLLVPRLCLHAKQLSFNHPVTGESLTFNCPVP------------------------------------
>UniRef50_A8RDU5(92-304:317) Pseudouridine synthase n=1 Tax=Eubacterium dolichum DSM 3991 RepID=A8RDU5_9FIRM  E=2e-54 s/c=1.00 id=29% cov=81%
-LSILYEDDLFLIVYKPSFMLVHSDGNETETTLydiVKGYYLLQGLDIPVRAIHRLDKETSGAVIFCKIPLLQPLLDYMLQEKQIDRQYLALCAKVLNDDLTIDKQIGR--DRHNAKKMRISKQGKSAKTDVHVIAQY-----------QDYTLIACKLYQGRTHQIRVHLASITHPLLHDTLYGNYDK--------RINRCALHAYRIQLCHPFTQQNITIECPLPTDMKKLVE----------------------------
>UniRef50_B1MZP7(78-296:300) Pseudouridine synthase n=5 Tax=Leuconostocaceae RepID=B1MZP7_LEUCK   E=3e-54 s/c=0.98 id=29% cov=82%
-LDIIFENEHWLVVDKPYGVTTVPGHADRLHTLVNQvkGHLEEINAEDlvPHVVTRLDRDTSGIVLLAKHRFAHAVLDQQLQDHTVEKFYLAYPSGILTEDhGDINAPIGRVEGDFIKREVRDD--GKPSRTEYWVERRYD---ENGEQPMTR---VKVQLHTGRTHQIRVHFKNIGHPLVGDDLYGGPLWH-------GLKRQALHAYHMRFYDPFIEDYREFNTKLPEDLK--------------------------------
>UniRef50_Q489H0(364-562:567) Pseudouridine synthase n=3 Tax=Gammaproteobacteria RepID=Q489H0_COLP3  E=4e-54 s/c=1.07 id=40% cov=75%
-LEIVFQDEHVVVVNKPAGLLSVPGKSIKDSVYTRIKTQFPQASGGL-IVHRLDMATSGLLMLALNERAHKHLQQQFMNKEINKRYVATIEGKLEKtSGEICLPLRGDFDDRPKQMVCHEHG-KYAETHWQLIEEVDNTSKLFLY-----------PITGRTHQLRMHCAHpdgLNLPIIGDSLYG-----------HSADRLHLHAQRLSFTHPITKELLTFE----------------------------------------
>UniRef50_D2RJW8(74-281:285) Pseudouridine synthase, RluA family n=2 Tax=Acidaminococcus RepID=D2RJW8_ACIFE  E=5e-54 s/c=1.02 id=33% cov=79%
-LSILEETELYLAVDKPAGLVTHNAGKERTPALsrrVAWYFQTHHISSAVHPVSRLDRETSGVVLFAKN----ACLHHMLSRNRLEKTYLALTLGhWEQPAGILDWPIGRRPGSIVER--QVDPDGQPARTRYQVLGEKE-----------GLSLVRFQLETGRTHQIRVHAAAAGHPLLGDTLYGTPG---------APGRHYLHAWKVAFREPFTGRPVEITAPLPPDFRKVW-----------------------------
>UniRef50_Q6MM51(1-228:231) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MM51_BDEBA  E=8e-54 s/c=0.93 id=34% cov=85%
MIEILFEDEFFLAAAKPAGMPSQATvdKSRQDFFTALKNQLRNERGDAFYLAlhHRLDRDTSGVMIFAKTKEANEPLADLFKTHKIQKTYLCLTKrtQKAADAWEVDNHLVEMKDTKLKktKMVRTQSGGDRAYTKFRKLEVFPEAL-----------LIEAQPLTGRMHQIRVHLADRGMGIYGDDIY-------QAPKNPVAPRLMLHAHALEFTHPFTKEFVRIECAVPADMAQFMKTLTFHS----------------------
>UniRef50_D1PDP7(339-551:556) Pseudouridine synthase n=1 Tax=Prevotella copri DSM 18205 RepID=D1PDP7_9BACT  E=1e-53 s/c=1.00 id=34% cov=77%
-VETLYEDRELAVIYKPEGLLSVPGKDAAQPSVYALMRRKYQEATGPLIVHRLDMATSGLMIIAKTEFAYHRLQKEFLNHRVQKKYVAIVCGKDKEScnrilkeaeggrGYISLPLIADFLDRPRQMVNREQG-KEAITEYEVLERIDDTHLR----------LALYPKTGRTHQLRVHCAHqegLNAPIIGDPLYGNE----------PATRLHLHAEEITFEHPMTGKKMTVT----------------------------------------
>UniRef50_A6G930(109-347:356) Pseudouridine synthase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G930_9DELT  E=2e-53 s/c=0.88 id=30% cov=86%
---VVHEDPDVLVLDKPGNLPVHPTARYHRHTLTALMRRRLGPKHGWEMAHRIDRETSGVIIFGRRKASGPKIKGSFFRREVHKEYLAIVLGRlelPEGPRLIDMPLGSAVGSKIMIKMgprPVDEGGLPAQTTIEVLAH-------GEHRGQPITLVRCLPRTGRTHQIRVHLAEIGHPILGDKLYAaeedeflavveDGEPVAELEARLGLWRQALHARALSLPHPTTGDGVRYVAPWPKELAGVIA----------------------------
>UniRef50_C7LZI3(80-308:309) Pseudouridine synthase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7LZI3_ACIFD  E=2e-53 s/c=0.92 id=31% cov=81%
---VCYEDDDVAVIDKPAGLIVHRThlrdvrPSVADWALERWPSLRALPGDPLrrGLVHRLDRGTSGLMVIALSAGAYESLRRAVHDHEVERRYRALVVGVPPQAARIEAPLGRDLRDLSRVAVVS--GGRDARTQLRVVWH-----------GPDTSLVELTLETGRTHQIRVHLSAIGHPIVGDEVYGVPYG--------GLERPFLHATALAFEHPTRPGRVEVTAELPEDLGELAAR---------------------------
>UniRef50_Q73NS0(88-339:345) Ribosomal large subunit pseudouridine synthase, RluD subfamily n=1 Tax=Treponema denticola RepID=Q73NS0_TREDE  E=2e-53 s/c=0.84 id=24% cov=84%
-LNIIYEDENIIVVNKERGMVTHPAGGNWDGTLVNALNYYRLYDSRIkdefavelnkllsgevknieklslepyrmGIVHRLDKETSGLIITARNLKTEKLLKSFFKKRAVKKYYLAVLDGVPPKNkGRIKTSVFRSSSDRKKFSVSADlSKGKKALSAYKVLKS-----------DGKMSLVLFRIYTGRTHQIRLHAKFMGCPVAGDKVYGKKKtglEKKTGLAKKTGMPLMLHAYKLIIPDTVNSKK-EFKAPIPNDFKQIL-----------------------------
>UniRef50_C7TK72(76-275:278) Ribosomal large subunit 23S pseudouridine synthase D n=8 Tax=Lactobacillus RepID=C7TK72_LACRL  E=2e-53 s/c=1.05 id=32% cov=77%
-LNTRYEDDDLLIVDKPAGMKTHPNQ--PGETGTLMNQAAAYLAPFPALItHRLDMATSGLLVIAKNPLAQAIINRQLTTKTMHRDYLAVVPSGIPEKGTIQAPIGHDPDDKRKRMIRAD--GAFAVTHYHRIAETADTAT-----------IELNLETGRTHQIRVHLASIGFPIIGDPLY---------AATETATRMQLHAFRVRLIRPLTIEPLTVTSPSP------------------------------------
>UniRef50_B5JHH9(89-322:324) Pseudouridine synthase n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JHH9_9BACT  E=3e-53 s/c=0.90 id=31% cov=81%
---IVYFDEHIVVVNKAAGLMTVPHP-ESDETETLDRLVNDYLRIRdpdaktnrasLGVVHRIDKDTSGLVVFARTFLAKRALSEQFRAHSIERRYLAIVHGELKAQSIRTHLVRETGDGLRGsapKGATNSEGeelGRLAITHVDVVERL-----------AGATLVSCRIETGRTHQIRIHLSEIGHPIVGEKVY----IRGFEGELIPANRAMLHAAELGFIHPGSGEAVSWQEEASKDFQR-------------------------------
>UniRef50_D1R6W7(84-292:295) Pseudouridine synthase n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1R6W7_9CHLA  E=4e-53 s/c=1.00 id=30% cov=79%
---IIYEDADLLVYDKPAGI-----NCDTSGIVRLIH----QKDPSLKLVHRLDRDTTGILLFAKTDAVLHKMIRLFKTFKVKKTYYVIVDGAIsKEKGVIDnnlAPLHKYQGQTVWGQATGSKGV-HARTGWR-----------KEKKGQDCTLIQCYPVTGITHQIRVHMSEMGHPILGDYQYG-----RRFICSYQPSRYLLHAYEITFPHPSSEKEIRLKAPLPSDFKQALDHL--------------------------
>UniRef50_A8U9H8(97-305:309) Pseudouridine synthase n=2 Tax=Bacilli RepID=A8U9H8_9LACT   E=4e-53 s/c=1.00 id=29% cov=80%
---ILYEDDAIIVIDKEAGLLSIAAKFAQELTAhrqLINYVKQENQNNRIYVVHRLDRDTSGVMVFAKTEKIKQDMQENWKEIVKERIYTALVEGVVREDEGTIKTWLTESKAMKVHSATYDNGGKLAITHYKKIRNNE-----------DFTLLEARLETGRKNQIRVHMETLGHPVAGDKKYG--------ATSNPLKRLGLHATTLALIHPTTGELVRFHSKVPKAFL--------------------------------
>UniRef50_B2UKZ0(21-256:258) Pseudouridine synthase n=2 Tax=Verrucomicrobiaceae RepID=B2UKZ0_AKKM8  E=6e-53 s/c=0.89 id=32% cov=85%
------ESGDWIVVDKGAPLIVHPSNGKKEpcllEGVEALLSYEIANGAALSLVNRLDRETSGLTLVAKHKRAARELGRAMQRRLIHKEYLAIVQEWPEwTETACTAPILRQ-GEVAESRIWVKQAVHPAGKACTTVFRKERTWNTRRGP---LALVRCIPETGRMHQIRVHLAHLGHPILGDKIYGPSEHcyleyiqhgwSRELEERLVLPRHALHACRLEF--PFDEETFTAEAPLPEDMRLLLE----------------------------
>UniRef50_Q04XF3(84-305:312) Pseudouridylate synthase, 23S RNA-specific n=4 Tax=Leptospira RepID=Q04XF3_LEPBL  E=7e-53 s/c=0.94 id=29% cov=83%
-LPVVLEREDYLIIHKPPGIASHSGPGDRSPSLVngLLHHFKELSKvggeARPGIVHRLDKPTEGLMLIAKNDRAHGKLSELFRKREIEKKYYAWIQGHLPaETGTIDLPIARHP--IERLKMTVSPKGRKSVTHYKVLKYVNSR------SGRKFSFVEVGLETGRTHQIRIHFQSQRCPVVGDLLY---SRTGSQFESYGLQ---LLSYYLKFKDPFTGEMIEATLALSERFLR-------------------------------
>UniRef50_Q5E092(373-576:576) Pseudouridine synthase n=3 Tax=Aliivibrio RepID=Q5E092_VIBF1   E=1e-52 s/c=1.02 id=35% cov=77%
-LEIVYEDDVLVIVNKPVeFLSV--SGKYISDSVHARIQARYPNATGPLIVHRLDMSTSGLLVLTLTAESNKQVQKQFIERTVEKRYTALLEGNIeTDNGTINLPLTGDMEDRPRQMVNH-KSGRKAETHYQVIAQ-----------EGKRTKVHLYPHTGRTHQLRVHCAHqagLNTPIVGDDLYG-----------FKADRLHLHAGYLKFKHPTTNETVEFSC--PEDF---------------------------------
>UniRef50_C8W9Q3(10-239:246) Pseudouridine synthase n=2 Tax=Atopobium RepID=C8W9Q3_ATOPD   E=1e-52 s/c=0.91 id=29% cov=84%
-LEFLYQDDYLLAVNKPAGMIVHSDGTNEPsltdlvcEKLCALESSNKIDLSQVQALNRLDKETTGIVLFSLKKETQPQFDQLIASKELSKEYLAVVKGDFgLNKLLIDKAIGKDRHDAQK--MRISDTGKPSQTEVRLIKVASSAQGQIQ------SLLLVNLLTGRKHQIRVHLSSLGFPLVGDVLYGGMSSlQRKTKKKHRPQPLMLHAYRIGFIHPVTGAKIVIKTDIPERF---------------------------------
>UniRef50_C7LR44(18-237:243) Pseudouridine synthase n=6 Tax=Bacteria RepID=C7LR44_DESBD   E=1e-52 s/c=0.95 id=33% cov=79%
---IIYEDRDIIVVNKPAGMLTMATETEKTRTAyyALTDYVRKGNAKsryRIFIVHRLDRETSGIVLFAKTEVAKRTLQDQWED--TTKIYAAVVHGQMgKASGMLSSHLVESGVHKVYAT-RDAALGKLARTAWTVLKE-----------RGGYSLLDVTLLTGRKHQIRVQMADAGHPIAGDKKYGVKGDT--------FSRLALHARSITFAHPFSGRSMTLDAPVPSVFAQL------------------------------
>UniRef50_D0MHX3(7-223:242) Pseudouridine synthase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MHX3_RHOM4  E=2e-52 s/c=0.96 id=35% cov=80%
-LPVLYLDNHLLVINKPSGL---RSQGDRSGAPTVLSLGKALIKERfnkpgnvyLGLVHRLDAPVSGVMVLARTSKAAARLMQQFRERTVEKVYLALVEGELEGSGTWEDFIA--PARDHMRLVPEDhPFGKRAVLHWQALMT-----------RNGLTLMRLVPETGRKHQIRVQLAFRGYPILGDRRYRARRWLAPGQ-------MALHAWKLALTHPTRRERMQWTAPVPSFWDEAF-----------------------------
>UniRef50_Q0BYW5(23-244:244) Pseudouridine synthase family protein n=1 Tax=Hyphomonas neptunium ATCC 15444 RepID=Q0BYW5_HYPNA  E=2e-52 s/c=0.94 id=33% cov=83%
----IHEDAAILGFNKPPGMASQGGSSVGQSLDDLLWAFAKSNGKRPRLVHRLDQGTSGVMLTARTQPAAAFLSAAFAGRDAQKTYLALVKGKLPpaEHGVIDASLVKVEEGGRPRMIlakPSRKGAQPARTGWAVLARNE-----------DHALMQLTPETGRMHQIRVHLMSLGCPILGDGLYGEGQAT--------APRVMLHAARLEVPHPEGG-TLTLEAPVPEDFRAAAEKAGLQAGL--------------------
>UniRef50_A3VN52(97-313:324) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Parvularcula bermudensis HTCC2503 RepID=A3VN52_9PROT  E=5e-52 s/c=0.95 id=33% cov=82%
---VIYEDDDILALNKPAGLAVQGGA----KTLIHIDGMLDVFGEgeaRPRLVHRLDRDTGGVLLLAKSRAVAATLSLAFQQHRIGKTYWAITKGVPHPLfGRIDMRIEKAGEPGREKM-RGTEQGQSALTDYQTVET----------AGQKAAFLALRPHTGRTHQIRVHLSAIGTPIVGDRKYGG-----AGAVLEGLPNQMhLFCRQMHV--PRRGRpPLVVTADLTGGMATSWSIFGF------------------------
>UniRef50_Q1JVY6(85-291:295) Pseudouridine synthase n=1 Tax=Desulfuromonas acetoxidans DSM 684 RepID=Q1JVY6_DESAC  E=9e-52 s/c=1.00 id=33% cov=79%
---ILYESREILIVDKPSGLAIHSSEGHQDRNLAALvdELIRSRGDAYqVAPIHRLDLETSGPVLFGKGKKACSELGKLFMCHEVEKSYLALVAGKTPGRGLI------------QSEVPSKGKTKEAQTAFQALDRNE-----------QASLLKVTLYTGRQHQIRRQLAELGHPLFGDRRY-------RGQQPDALPRLFLHCCQLAFIDPFSGAPVEINSPLPADLSQFLDTVGLR-----------------------
>UniRef50_C6XLD8(41-264:272) Pseudouridine synthase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XLD8_HIRBI  E=9e-52 s/c=0.92 id=36% cov=82%
------EDDSILAFNKPSGLACQtRSPADRTFDA-LLQVYVKRNGKRPRMLHRLDMLTSGVIIAARTKPATSFFQQTFERREAYKSYLAIVRGPAFEksEGVIDAHLQRYQKEPNLALMRpcdvDGEGAQDARTRYLVLSS-----------QNDYHFLLLTPETGRTHQLRVHLEHFGRPILADPYYG----TDALEGSYQPARLMLHAYRLLTPHPDGGE-IDIIADVPDDMKECLTAL--------------------------
>UniRef50_A4A1L7(9-229:250) Putative 23S rRNA pseudouridine synthase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A4A1L7_9PLAN  E=1e-51 s/c=0.93 id=31% cov=83%
-VDILYEQGPCFCIAKPAGLLTqappHIDSLESRFKAFIRQRDFKTGKVYLGVPHRLDRPVSGVLTFARNVRAARRISQQFETRLVRKLYWAFVAGQPPdDQGVWEDPIRKIPDvAMAEIVSPSDPGARWAKLKYEVLQRTEQG-----------AWLEIELDTGRYHQIRVQCASRGFPILGDVSYGGEIPFGPQSEDERARHIALHARYLRLKHPMVDEIVAVTAPLPESW---------------------------------
>UniRef50_A9GHW4(113-347:356) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GHW4_SORC5  E=2e-51 s/c=0.87 id=27% cov=87%
---VVYADASVVVVNKPAGVSTIPygdeapaeqaATLDALVREVLARRDRLRGRAPLGVVQRLDKGTSGLLVFARTLAAKKHLAQQLRVRAMHRQYLALAHGAVPRGTYRSYLVEDRGDGLRGSARDGRREGQLAVTHVEPIEVLRGP--QEGAGAGGVTLVACRLETGRTHQIRIHLAEAGHPLVGETVY----VRDYRGTKVPAARLMLHAAELGFDHPADDRPMRFQAPPPPDFDDVLERL--------------------------
>UniRef50_D2R4N0(89-312:313) Pseudouridine synthase, RluA family n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R4N0_9PLAN  E=2e-51 s/c=0.91 id=33% cov=82%
---IVYEDRHLIVVEKPAALLTVPTPKNDRGTLlerVANYVKIVSRGKGAFQVHRLDRGVSGLLIFGKTTELAQMLRDQFAMHKPEREYVAIVRGKLdKPEGMIESFLA--TDRDLNRYSTDDESiGQHAVTHYRVIEEL-----------AGASVVQVWLETGRRNQIRVHFAEAGHPLIGDQRY---RADEAADTRWTHARIALHARLLGLSHPMTGEPLRFESPLPHEMKNFI-----------------------------
>UniRef50_B0N6U2(90-297:328) Pseudouridine synthase n=5 Tax=Bacteria RepID=B0N6U2_9FIRM   E=3e-51 s/c=0.98 id=33% cov=76%
-FSVLYEDKHVLIVFKPAGLLVHEDANESINTLTnqVLSYLASKNELDlsrentfmPGPVHRLDRNTSGIVIFGKTLAALQNLNEMIKQRHcIEKKYLTICRGQLNHQRNLHGYMIKLENQAQVKLVKKDYPG--ALT----METIVRPLKY----NCDYSLVEVTLITGRMHQIRVHLSSIEHPIIGDRKYGDFELNKYIKKTFGLNNQLLHAYKIKF----------------------------------------------------
>UniRef50_C6V544(94-303:305) Pseudouridine synthase n=2 Tax=Neorickettsia RepID=C6V544_NEORI   E=1e-50 s/c=0.96 id=30% cov=80%
----LYEDENVLAIDKPFGFPVQSGYGITTSIDNAM----KSINPEYRVVHRLDKHTTGVLIFAKTLDAARELWRLFSNRLVKKRYLAIVIGELKEkKGAVDCYINKVLFKGEEVMQCNHIGnGEHAITQFHVIKKFK-----------NASLIELFPLTGRKHQIRSQMASIGHPVLNDGKYGRREAFLECSVN---KKLCLHACEIEFE--LFGKIIKVTAELPVHFAENLA----------------------------
>UniRef50_B9YDX4(84-294:295) Pseudouridine synthase n=1 Tax=Holdemania filiformis DSM 12042 RepID=B9YDX4_9FIRM  E=2e-50 s/c=0.95 id=32% cov=77%
-VRILYEDELILAVSKPAGMIVHPDNKGKTGTLanaVAAYYLRTGQHCTVRPIHRLDEGTSGIVLFSKCPFFQPKLDQALAQKQIARTYLAVVSGVmkPKDRLTLDKPIGR--DRHNAKAYRISPTGKPAVTHVEVLRCRQKEKQ---------TLVRCQLETGRTHQIRVHLASIQRPVVNDPLYNPRPVQ---------GRMKLHAWKCAWTDLVSGRQVEIT----------------------------------------
>UniRef50_Q6MJF7(13-227:230) Pseudouridine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MJF7_BDEBA  E=2e-50 s/c=0.93 id=31% cov=81%
-FEILHEDLDVIVGNKAAGVLTVAAKWDRDNTVHNLLNLyvrkgNPRSNKCVYVVHRLDQATTGVLIFAKTEQVQHFLKDDWKS--TIKTYYAIVHGKmPKKSGTITSYLEEDENYVVHSSKDSDKG-KLAITEYEVLKETE-----------KFSLLKINLLTGKKNQIRVHLAGEGHPIVGDPKYGKPTTN--------LKELRLHSASLEFTHPHSKKRITIKAPVPNYFRTLID----------------------------
>UniRef50_B0JGC2(300-500:501) Pseudouridine synthase n=2 Tax=Microcystis aeruginosa RepID=B0JGC2_MICAN  E=2e-50 s/c=1.00 id=34% cov=77%
-LEIIYEDEGIIAINKPAGLLSVAGRYQDSQDAVVNRFRRQ--GKNLIPVHRLDRETSGILLLAKSLDIYRCLSQQFQRREVEKIYEAILSEIIeRESGIIDLPLWGNPQNRPYQTVDWQRG-KASQTYFKVVGK-----------EGNYSRLEFIPYTGRTHQIRVHSQQgLGIGILGDRLYNGKQSD----------RLHLHAKQLSFRHPQTENKLDLIIPTP------------------------------------
>UniRef50_Q31NG5(338-542:543) Pseudouridine synthase n=2 Tax=Synechococcus elongatus RepID=Q31NG5_SYNE7  E=3e-50 s/c=0.98 id=36% cov=72%
-LPILYEDADLLAIIKPAGLLSVPGTRG-LQQASAIQLLRQQFPDLPTycVVHRLDQATSGILLVARNRPTQVALFEQFRRRQVHKVYEALLEGQPDcTAGTIDLPLRPDWTRRPYQLVDRDRG-RPALTYYRCIDQTGDRCR-----------MELEPITGRTHQLRVHMAHpegLGQPILGDDLYGQSS-----------DRLYLHARSIRFRHP-------------------------------------------------
>UniRef50_B9XHZ1(379-597:599) Pseudouridine synthase, RluA family n=2 Tax=Verrucomicrobiales RepID=B9XHZ1_9BACT  E=4e-50 s/c=0.91 id=27% cov=83%
-IQILHEDEALIVLNKPAPLPMHaGGRFNRNTLEYILHQVYH--PQKPRAAHRLDANTSGVVLVTRTRHFASHLQPQFAHGEVGKFYLVKVQGTPKEDSfSCNAPISAEPSEAGAREVDFEEGL-PSRTEFRVLQRNADGT----------TLLEARPLTGRTNQIRVHLWQMGLPVCGDPVYlPGNKLGETQTLRVEDAPLCLHAWRVTFLHPLHRQRMEFTAPKPEWAMQV------------------------------
>UniRef50_A6GAA8(88-305:311) Pseudouridine synthase, RluA family protein n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6GAA8_9DELT  E=4e-50 s/c=0.92 id=32% cov=83%
----VHRGEDFVVLDKPAGVPVSAvreTCVGSLSEALIHQLESEGLErPYVGVVHRLDQGASGLVLFTIRDVANKSLHKQFRDHEIRRGYRVRVTGEPPAQLRCDAPLIKLRSGGVKVGSPGDGRSKPATTHFRHVARVDGEAGPEH-------LLDVEIETGRTHQIRAHAAHLGFPIVGDRRYGADGEGEAGSDH---SRLCLHARSLEFEHPLTGAPQSFTCELP-DWAQ-------------------------------
>UniRef50_Q26D11(358-560:561) Pseudouridine synthase n=2 Tax=Flavobacteria RepID=Q26D11_9BACT   E=5e-50 s/c=0.99 id=33% cov=77%
-MEVIYEDDAIIIVNKPEEFLSVPGKTIKDSVYSRLKELYP-DATGPILVHRLDMSTSGILVATKNLEYYHFIQEQFINRTISKRYVALLNGVLeNNEGMIELPLRVDLDNRPTQLVCYEYG-KSARTKYQVLERREKE-----------TLVHFYPITGRTHQLRVHAAHasgLNAPIVGDDLYGT-----------ATNRLHLHAEFIKFIHPITHKTVSFKAPVP------------------------------------
>UniRef50_B2G9U4(91-304:309) Pseudouridine synthase n=14 Tax=Lactobacillus RepID=B2G9U4_LACRJ   E=5e-50 s/c=0.93 id=29% cov=82%
-LEVLYENRDLLVVNKPRGQKTHPNYHGETGTLMNdVAGYLAHSQNNAYMVHRIDLQTSGAVIVAKNPIVVPILNRLISDGQIHRQYLAVVEGEMAQSGKLDWAIGRNPVNPHL-HQVNGQNAQPALTYYETLAS-----------NHERSLVKLRLATGRTHQLRVHLAHSGHPIVGDPLY----------NPSSTEGMLLHGVSQKLILPFVMKSLNISAPLPSYFKNYLVKYN-------------------------
>UniRef50_A6GHA7(87-312:324) Pseudouridine synthase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6GHA7_9DELT  E=6e-50 s/c=0.88 id=29% cov=82%
-LTVVHEDASLLVLDKPAGMVVHAGPGHDSGTLVnaVLHHLQvhadalpvlpGNGPERPGVVHRLDKDTSGLIVFARGLRAQTVLAEQFRDHSIDRAYLGVVLGRPSfERRRLETTHGRDPAD--RRRFAPDQGTRRAVTTMEVL----------RPLGAHAALARFTLETGRTHQIRMHARMVGHPIFADPLYGRRPKHPALRRlADGLGRHALHAALLGFAHPDGSGRLVLEAPLPP-----------------------------------
>UniRef50_B0PEI9(101-304:338) Pseudouridine synthase n=5 Tax=Bacteria RepID=B0PEI9_9FIRM   E=8e-50 s/c=0.98 id=31% cov=74%
-IDIIYEDENILLVNKPAGLVVHEDEHQSSDTLINriqhhlyncgVYNPAEENSFAPALCNRIDRNTAGIVIAAKNAAALRILNEKIKARELQKLYLCIVHGTMPKESdTLKAFLRKDARtNTVAVYDHPIPDGRTILTHYRVVAQKD-----------RLSLLEIDLLTGRTHQIRAHLAHIGHPLLGDAKYGRNRDN----HKTGLKHQALCAYKLTF----------------------------------------------------
>UniRef50_B4D5D1(18-251:265) Pseudouridine synthase n=1 Tax=Chthoniobacter flavus Ellin428 RepID=B4D5D1_9BACT  E=9e-50 s/c=0.85 id=29% cov=83%
------ETADWLVVDKPPFMEAHPSKPNGRPTLWdglrGLLAYEIVNGGQVSIINRLDRETSGLTLVAKHRAAARELHLQMQGRRVEKEYLALVWGWPERETfTIDAPILRQgecMPSPIHLKQAVHPDGAAARTRFQVECTFTLETSNG----NRFALVRAFPETGRTHQIRVHLAHAGHPVVGDKIYGPDEQcylefirtgwTPELGSRLLLPRHALHSTVLRL--PDAG--LAWRTPLAPDLMSW------------------------------
>UniRef50_A3MZ33(32-233:237) Pseudouridine synthase n=9 Tax=Proteobacteria RepID=A3MZ33_ACTP2   E=1e-49 s/c=0.99 id=40% cov=77%
----VYRDNHILVINKPSGLLSVP--GNRPEYYDSAMTRVQQKYGFTEPAHRLDMATSGILLFALSKAAEKELKRQFRDREPKKHYIALLWGKLGEKvgdtGEMNFPLICDWENRPRQKICYERGKK-AITHYEVLAH--LPNNTTR--------VKLTPITGRSHQLRVHSLALGHPILGDKFY------ASPLAKSLSPRLCLHAESLSITHPITGEAMTFTA---------------------------------------
>UniRef50_Q04HA3(84-300:302) Pseudouridine synthase n=2 Tax=Oenococcus oeni RepID=Q04HA3_OENOB   E=1e-49 s/c=0.92 id=29% cov=80%
-LRILSEKEDYLLVDKPAGMKMHPHSPNETDTLLNYveaqlkGHLSRSCPAHAFMVHRIDRDTSGVVIIAKNPLAVGILDQLLAKKRIKRTYLAWVSGNLeNKKGSIDQAIAVDPINPYKRIV--DQAGQKAVTHWTKIHTVYQN-----------TLVRVSLETGRTHQIRVHFAAIGHPIVGDHLYNGLAY----------SRLLLHSATIEIPelFSESRQSHTITTAIPKDFPRQLK----------------------------
>UniRef50_C8P137(71-280:291) Pseudouridine synthase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8P137_ERYRH  E=2e-49 s/c=0.94 id=30% cov=79%
-LQILYEDKDILVVDKPYKLLTV--SNRKEEELTAFRLASDYVKKqdsknRIFVVHRLDQDTSGVLMFAKSEYVKRLYQDKWSELVDERLYVAIVEGVVPKDKDV---IRSFLRQNKTTHMYSTSSGQEAITNYEVIKRTENN-----------TILKIQIDTGRKNQIRVHMNDIGHPIIGDKKY--------DAKTNPLKRLGLHAYRLRVMNPKTKKMMTFVSPLPPKFKKL------------------------------
>UniRef50_Q6MDB9(84-292:298) Putative uncharacterized protein n=1 Tax=Candidatus Protochlamydia amoebophila UWE25 RepID=Q6MDB9_PARUW  E=2e-49 s/c=0.95 id=31% cov=80%
---ILYEDEDLFIYDKPAEMNC--------DEQGIIALLRPSF-PSIQLIHRLDRQTTGVLALAKNKTTFEALVNQFKQLKVSKSYRAIVDGILTSSkGHIENYLGKKHVYQGQSIWGEVPSfqGLYASTYWSCLE-----------IGKKASLVRCFPKTGRTHQIRVHLAGLGHPILGDYQYG-----KKFTCLYNPPRYLLHAEEMGFIHPRTRQKLIVQAILPEDFLGAYKKL--------------------------
>UniRef50_C8QW29(88-325:334) Pseudouridine synthase n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8QW29_9DELT  E=2e-49 s/c=0.83 id=29% cov=85%
-FSVVYEDDDLLVVNKPAPLPCHPGGRYFRHTLWRLLQERCGVPKPL-LVNRLDRETSGLVVVAKKRAAARDCARQWQEQQVEKRYLVLVEGEFPlGAQAVAGFLAPDPASLVRKKSRFFPADQAApagavscATAFRLLA-----------LQGGISLLEARPLTGRCHQIRATLCSLGFPVVGDKIYGldeelflrflADRLSSDDRRRLRLPRQALHSAGLKMRHPADHRPLEFTCPLPPEMAGLLPQ---------------------------
>UniRef50_Q12L72(27-224:230) Pseudouridine synthase n=17 Tax=Shewanella RepID=Q12L72_SHEDO   E=2e-49 s/c=1.00 id=36% cov=75%
-LDIRYLDRDIIVINKPSGLLSNPGraPETYDTAITRLQRLYPET----ILIHRLDCDTSGIMIFARNKKAESNLKTQFQNRQAKKVYIAEVSGCFeHQDGKVNFPLG--PDPMTPPFQQVIESGKPALTYYRLLEHRAST-----------SLVELKPHTGRTHQLRVHMKALGHTIIGDEFYGDETVIAAS------HRLNLHAQSLTLLHPFKQIEIQF-----------------------------------------
>UniRef50_B7VRG6(360-560:563) Pseudouridine synthase n=4 Tax=Vibrionales RepID=B7VRG6_VIBSL   E=3e-49 s/c=0.98 id=34% cov=76%
-FDIVYEDDEIVVVNKPEEFLSVPGKFIEDSVYTRI-KARYPDATGPLIIHRLDMSTSGLLILALTAESNKHIQKQFIDRTVEKRYTALLDGEIDgKSGDISLPLRGDITDRPRQLVCHEHG-RNAETHWEAVST-----------NNGKTKVHLYPKTGRTHQLRVHCAHpsgLGVPIRGDDLYGYKRE-----------RLHLHAGYLKLIHPTTGEWIEFEVP--------------------------------------
>UniRef50_D0LYX0(92-343:345) Pseudouridine synthase n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LYX0_HALO1  E=3e-49 s/c=0.78 id=31% cov=87%
VLDLLYEDDAIAVVSKPAGLPSHPLRAGERDTLANALVAHYPecaaigaDPREAGLAHRLDIDTSGVLVAARTQKAWHALRAAFGSGAVEKHYLALTFGAP-SSGEMDVALVQRGRRAHPVFRDDagfggfggrgeRGDALPARTTWRIERRF-----------GPACLLLCRAHTGRMHQIRVHLALAGAPIIGDSLYAPAPETLSAAeredlaalsEHPEATRHFLHASAVTIPHPETGRALRIEAPLPEGRAQFLAELSRR-----------------------
>UniRef50_B3T0Q8(94-313:320) Putative RNA pseudouridylate synthase n=2 Tax=prokaryotic environmental samples RepID=B3T0Q8_9ZZZZ  E=4e-49 s/c=0.90 id=26% cov=84%
---VIFENDSFLLVNKPSGLAVHGGSGIHLGLIELLRSFREKRNEHLELVHRLDKDTSGCLLVSKKKSKLRKLHEYFREGKVKKTYLGLMVGKFTQTVyEIDQPLKIITTPENGRLAVPDDSGKKAKTKFFLMEKYKNS-----------ALFKIEPITGKTHQIRAHAKYMKTPLAADNRYGIQPDQ--IVSEFGLTRLFLHAESITFPgLSSTENTFSFKSKLDTKLIEVLEKL--------------------------
>UniRef50_C4ZBX3(5-244:244) Probable 23S rRNA pseudouridine synthase n=1 Tax=Eubacterium rectale ATCC 33656 RepID=C4ZBX3_EUBR3  E=4e-49 s/c=0.82 id=28% cov=84%
--DIIYEDNDIIICYKPAGIATQTRRIGQQDMESFIRNYRAAKNEppYVGIVHRLDQPVEGVMVFAKNQKAAASLSRQIKEHTTEKYYRAAsrgqgVSGADKEEdnhdsawhTLTDYISFDKRTNTSKITSEKDRLAKKAVLQYRVISvTPDRDSSQNECIRTEF---DIKLLTGRHHQIRLQLAHIGYPLIGDTKYGKPASNNSGTGSKSgrtcggvREQLALCSYKIVFDHPATGERMTFELP--------------------------------------
>UniRef50_A6TAT3(48-258:263) Pseudouridine synthase n=57 Tax=Bacteria RepID=A6TAT3_KLEP7   E=6e-49 s/c=0.93 id=34% cov=81%
-ITLLYQDEHLVLINKPAGLLSLSGKDPRNLDSVHHRLVQRYPGCTL--VHRLDFGTSGLMVIARNKGINALLCQQFSQRTVDKVYTALLCGHLAEdEGIVEAAIAKDPARF-PRMALCARHGKPARSRYRVIDRLYQAREGERALA--LTRVTLTPETGRTHQLRIHCQLLGYPILGCDLYGG----RELPGTEQAPRLMLHASELRFVHPVSHEPMHIQ----------------------------------------
>UniRef50_Q8DCG0(15-211:250) Ribosomal large subunit pseudouridine synthase A n=82 Tax=Proteobacteria RepID=RLUA_VIBVU  E=8e-49 s/c=0.99 id=30% cov=76%
--EIIFEDDHILAVNKPSGLLSVPGRL-PEHHDSMWSRLQEQY-PEIQVVHRLDMSTSGLMVFAKNKRAEAALKKQFQYRLTHKVYYARVWGHVeADSGMIDLPLICDWPNRPMQKVCHEHG-KPSQTAFQVAKR------EVHANGAQTTIMRLLPVTGRSHQLRVHMQALGHPIVGDEFYAQGDAFTFS------ERLELHAAELSFYHPKS-----------------------------------------------
>UniRef50_A8VZ12(91-301:305) Pseudouridine synthase n=1 Tax=Bacillus selenitireducens MLS10 RepID=A8VZ12_9BACI  E=2e-48 s/c=0.92 id=31% cov=80%
-LSIRYEDEWCIVIDKPAGLLTIPNETYENDSVAGRVIGYFKSCDHPatfHPVTRLDRQTSGLMLIAKDRHSHSLFMKQQCAGLIDKEYVAVTpPGFPWIAATVDAPIARHPDSIIERMVHHE--GQKAKTR-----------LVKVNENASGSLIRCKLETGRTHQIRVHLAFTGWSILGDGLY---REEKSADEH---KRTLLHACSLRWDEPFTGERIEIHESVPEDF---------------------------------
>UniRef50_C6VIZ5(87-293:300) Pseudouridine synthase n=3 Tax=Lactobacillus plantarum RepID=C6VIZ5_LACPJ  E=2e-48 s/c=0.94 id=34% cov=77%
----LYQNSDLLVVDKPAGVKSHPNQPGETGSILNdLAATLQPTQQVPYMVHRLDQMTSGAMLVALNPVVVPILDRLISDKQIRRTYYAWVRGHFAtPTGHFTAPIGHDATDKRKRWVNT-ADAQPALTDYEVCAT-----------TAHQSLVKLTLHTGRTHQLRVHLAASDHPIIGDPLY--------DSQAESAPRLMLHAQLLDLQLPFSTTRVTVPAPLP------------------------------------
>UniRef50_A9GP63(19-261:666) Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GP63_SORC5  E=2e-48 s/c=0.80 id=37% cov=85%
---ILAEDGDLIVVDKPAGLSTHAPEAERIDDMVtrlrAFLRGRGDAEAYLGIHQRLDRDTSGVLLFTRRREANAAVARQFEGRTVQKTYVAAVSGFgdRPPRGTLRHRLVPAPGGAMRALaesggAREDRAAKredRAAGREDRAAKREDRAASGVLAITRYrllerrgdrALLELRPETGRTHQLRVQLAAIGLPIAGDPLYGGPE----------APRLLLHAAELRLDHPATGAAATFRSRLPAVFEAWLA----------------------------
>UniRef50_C0FY60(59-270:294) Pseudouridine synthase n=1 Tax=Roseburia inulinivorans DSM 16841 RepID=C0FY60_9FIRM  E=2e-48 s/c=0.92 id=31% cov=78%
-LQVVYEDDDVIIINKPSGMLSQkavPEDISANEYILSYLIRKGALSEEqfktfkPSICNRLDRNTSGLLIAGKTLKGLQTMAEALKKRTVQKYYRCIVKGELREKTHLKGYLSKDEQNNKVKVVSHIRPEEKA--DYLPIETEYRPVAV----SNGYTELEVHLITGRSHQIRAHLASIGHPIVGDGKYGDLRTNERFRKEVHVRSQLLHAYRIVL----------------------------------------------------
>UniRef50_B8CCD9(92-336:337) Predicted protein (Fragment) n=2 Tax=Thalassiosira pseudonana RepID=B8CCD9_THAPS  E=2e-48 s/c=0.79 id=28% cov=83%
-LDVVYEDEHIVVINKPSGVLTVPGKDDnpSLNKVVFERFGCESNRMDKMVVHRLGMDTSGLVVFARTNSALRELNSLFRTRKVTRKYEALVCGHLaKDSGDIDLSLMRDYEaliglDSGEVGKKLLESPKESMTKFEVISKEEMN-------GKKVTRIALTSISGRTHQLNVHCAAIGHPIVGDTVYGFGGEaapnggleesdlpedrasealQKDIAEAVAGKPMCVHAKSISFDHPVTKEALSFDCAAP------------------------------------
>UniRef50_C5DEF5(184-353:610) KLTH0C08756p n=2 Tax=Saccharomycetaceae RepID=C5DEF5_LACTC   E=3e-48 s/c=1.14 id=30% cov=65%
-IKIVFEDQDLFVIDKPSGIPVHPTGRYRFNTIT--KILQKQINGSVHPCNRLDRLTSGLMFLAKTPRGADHMANQLKAREVKKEYIARVVGEFPAERIsVEKPLKCVEPRLALNGVcnSEEEGAKEAKTVFTRVS-----------FDGETSLVKCQPHTGRTHQIRVHLQYLGHPIANDPLY-------------------------------------------------------------------------------
>UniRef50_Q0VQA6(26-228:229) Pseudouridine synthase n=7 Tax=Gammaproteobacteria RepID=Q0VQA6_ALCBS  E=3e-48 s/c=0.96 id=32% cov=78%
----IYRDEHLLLINKPAYLLSVPGRA-PENKDCAIRRLQQRY-PDIRLVHRLDLDTSGIMVFGLTAFAQSKLSRLFQLRTVKKRYQAIVHGLVEKNaGSIDLPLIADWPKRPLQKVCH-ETGKNALTHYRVLE---------RDIPGNRTRLALSPVTGRSHQLRIHCRELGHPIIGCDMY------APAEIEALSPRLLLHAEWLAFNHPLTGLWQEFTSPCP------------------------------------
>UniRef50_A6DHD2(93-326:328) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DHD2_9BACT  E=4e-48 s/c=0.82 id=27% cov=83%
-FKVVYEDDDILMVEKTGDLPVHPAGSFFKNTLW--YMLVKQFG-NVHIMNRLDRETSGLVLIARHHKAASVLGKQFERRQVGKEYDVLVEGLVSWDQY--DALGYMGPAVSSKIRKKfsfteaedwqDYGKHSARTEFSVLRR-----------SHELSHLHCRLHTGRTHQIRATLLSLGFPLVGDKIYGldeqfflsfiDGALTEQDYQKMRLRRQALHCSLMSFTHPMSGEDVVFESSLPKELAELI-----------------------------
>UniRef50_C9L5B3(30-234:244) Pseudouridine synthase, RluA family n=1 Tax=Blautia hansenii DSM 20583 RepID=C9L5B3_RUMHA  E=4e-48 s/c=0.94 id=29% cov=78%
---VLYEDKYILVCQKPAGFPVQSKRLGTLDMECALRNYLAKKGQEPYVAviHRLDQPVQGVLVFAKDKESAAKLSKQMQQGKFEKTYLAYTQGHTdkKQETLIDELEKDGRTNTSKVVAKKTANSKRAELSYKVLKETEEG-----------SLLEVSLKTGRHHQIRVQLAHAGLPIFGDAKY-----NVKCTKEDANHGVSLCAYKLSFLHPAKGKKMEFQ----------------------------------------
>UniRef50_A8RUB2(119-353:366) Pseudouridine synthase n=3 Tax=Clostridiales RepID=A8RUB2_9CLOT   E=1e-47 s/c=0.82 id=29% cov=75%
-LDIVYEDQHILVVNKPSGMLSQKAKdSDMSLNEYILNYLIDSGKLpisqlrtfKPSICNRLDRNTSGLVVAGKSLAGLQVMNEVFKDRSIHKYYQCLVAGEIKEKQLIAGFLKKDEsTNTVSIFPLEVEDSVPIMTEYLPLS-----------GNKTFTLLQVTLITGRSHQIRAHLASIGHPIVGDYKYGSRSLNDAVKKKYAVRSQLLHSWRL------------------------------------------------------
>UniRef50_C9LG01(7-229:245) Ribosomal large subunit pseudouridine synthase family protein n=4 Tax=Bacteroidetes RepID=C9LG01_9BACT  E=2e-47 s/c=0.86 id=31% cov=79%
-MEILYEDNHIIIVNKQAGEIIQGDkTGDRTVADEIKAYLKEKYNKpgavFLGIPHRLDRPVSGVSIFARTSKALARLNEMFRKGEIEKTYQAIVIHEPqIASGTLVHWLTRNEKqNKAYAHKAPQKNAKKAILDYKVEAKSD-----------RYWLINVQLQTGRHHQIRCQLAAIGCPIKGDLKYGAPRSNADGS-------ICLHARSIRFEHPVSHKIIFAEAPYP------------------------------------
>UniRef50_UPI0001C353AC(5-218:239) putative pseudouridylate synthase n=1 Tax=Clostridium hathewayi DSM 13479 RepID=UPI0001C353AC  E=2e-47 s/c=0.89 id=32% cov=80%
-MNILYEDDQIIVVEKPAGIESQSSRTfEPDMVSEVKKHINslspKKGDPYVGVIHRLDKPVGGILVFGKTKEAAGALSKQISEHQTEKRYLAVVCGKPVENfgTYVDYLWKDGKNNISKIVDKGITDAKRAELSYRVLAELEGE-------GGPLCLMEIDLKTGRHHQIRVQLSGHGTPLLGDLKY-----NPDGPKVTGQRNVALCAWKLSFTHPGNKKRMKFT----------------------------------------
>UniRef50_B7KI53(85-307:308) Pseudouridine synthase n=12 Tax=Cyanobacteria RepID=B7KI53_CYAP7   E=2e-47 s/c=0.86 id=28% cov=83%
-FDLLYSDSDVLVVAKPAGLPILPGGGFVEHTL-LGQLKQHYPEDTPFPIHRLGRGTSGLVLLARSSFARGFLSEQMRSRQISKIYRALIpKSDLTDHFTINQPIGKIPHPVLGYIFGATPNGKDALSECRVLKR-----------TSETTLVEVKILTGRPHQIRIHLAAIGYPLIGDPLYtmGGIPKIQTPITPEKLPvpgdcGYYLHAYQLTFNLPHRESPLTVTCPPPREL---------------------------------
>UniRef50_C4Z0B5(91-316:333) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Eubacterium eligens ATCC 27750 RepID=C4Z0B5_EUBE2  E=2e-47 s/c=0.85 id=27% cov=83%
-LDIIYENSDVIFINKPSGMLSQKAKPEdvSLVEYLIAHLIHkgelnagDLASFKPGICNRLDRNTSGIVAAGKTTKGLQQLSEAFKQRTLGKYYLCIVKGNVDKRALIKGYLYKDNKTNKVTISRtETKDSLPIETEY-----------IPVCSNGNVTLLKIHLLTGRSHQIRAHLASIGHPLIGDYKYGQKSVNDTFNRQYKVKDQMLHSYELDIPD----MDIHIYAVIPDSFKNVMK----------------------------
>UniRef50_B6IR13(12-197:242) Pseudouridine synthase n=1 Tax=Rhodospirillum centenum SW RepID=B6IR13_RHOCS  E=3e-47 s/c=1.02 id=33% cov=72%
---VLHRDADVLILDKPHGLPVHYGTKTVEHLEQYLPWIAFEREEPPRLAHRLDKDTSGCLVLARDAEVAARLGRLFLHGHVGKTYWAVVLGRPRgDAGRIDLPLLKVHIPGCSK-VVVDPDGKPALTDWRLLAT-----------DGRLSWLELTPRTGRMHQLRAHCACSGFPILGDPIYG--------AEQPPPVPLHLHARTVSF----------------------------------------------------
>UniRef50_Q1PXB6(75-272:274) Pseudouridine synthase n=1 Tax=Candidatus Kuenenia stuttgartiensis RepID=Q1PXB6_9BACT  E=4e-47 s/c=0.96 id=34% cov=75%
--DILFNDDCYVIVSKPPGIVT-------NGQNSIERDLRTQFNRdRIQAVHRLDKDTSGALIFAKNENAFEEMKKVFKKHDIQKIYRVIVTGKICEPAfTINSPV----------------GGQTAVTHITLLKKGKNT-----------SYLEVATETGRRHQIRIHLASIGHPVIGETEY--ARKEIENILHREAKRQMLHAHRISFVHPYTKKEISVTAPISHDFIQCL-----------------------------
>UniRef50_C4Z9Y6(93-322:324) Pseudouridine synthase n=1 Tax=Eubacterium rectale ATCC 33656 RepID=C4Z9Y6_EUBR3  E=6e-47 s/c=0.82 id=33% cov=83%
-LGVVYEDDDILAANKPVNMLSQKSKetdISANERLIGYLIKEGKLDfdtyksFKPSVCNRLDRNTSGLILMGKSLHGLQYLSQVLKARTAEKYYMALVAGEVDEPMTIEGFLTKDEAVNKVQITREPISDEslPIKTAYRPLKTIDMSASCHK-----ATLLEVHLITGRSHQIRAHLSSIGHPIIGDIKYGDRRINAFYKENYHVTSQLLHAHHVILPD---GRY--IEAALPDIW---------------------------------
>UniRef50_C0R003(18-232:241) Pseudouridine synthase n=2 Tax=Brachyspira RepID=C0R003_BRAHW   E=6e-47 s/c=0.88 id=28% cov=78%
----IYEDNHIIVAVKPPNI---PTQGDITGDVSFFENIKDYIKIKynkkgnvfLGLVHRLDRPVSGIIVFAKTSKAASRLSEAIRDRKFEKTYYAVVNGIlLEKEAKLENYLIKKTNKLGNIAQVVfenTKNAKIAKLKYNVIKE---------DVIKNLSLLRIELETGRFHQIRVQLANIGHVIYGDRKYGSY-----IKYDRNDVPLALFAKSLRFPHPTRDEEIYVEADLP------------------------------------
>UniRef50_B1Y046(43-254:256) Pseudouridine synthase n=43 Tax=Proteobacteria RepID=B1Y046_LEPCP   E=7e-47 s/c=0.89 id=34% cov=78%
LIDILHHDDSLLVVRKPAGLLSVPGRGEHLQDCVAARV--QAIWPDALIVHRLDMATSGLMVMARGPAAQRALGSAFEHRSVTKQYVAVVAGDVAgDAGSVDLPLCADWPN-RPRQKVDAAMGRPSLTHWRRATPAHEGSTTGDIDRTR---LELEPVTGRSHQLRVHLLALGHPILGDTLYAPDAVQRMA------PRLLLHASRIALPHPAGG----------------------------------------------
>UniRef50_A6ESW1(87-291:300) Pseudouridine synthase n=1 Tax=unidentified eubacterium SCB49 RepID=A6ESW1_9BACT  E=7e-47 s/c=0.92 id=33% cov=78%
-LKVLFEDNHLAIIHKPAGVEVSGNKKYTIENALPSLLKKSNQKdalDRPLPAHRLDYPTSGCLLIGKTSETLQALHRMFEKREISKKYIAVTLGNQITEGKIDKPI----------------DDKASLTTFKTLQTITSKKYNA------LNLVLLTPHTGRRHQLRKHMMQLGNPIFGEKTYGDINDQGKGS------GLFLHAIALSFKHPIDNKTLIIKSEAPRKFQKLF-----------------------------
>UniRef50_D2R795(80-338:341) Pseudouridine synthase, RluA family n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R795_9PLAN  E=7e-47 s/c=0.73 id=30% cov=85%
-VRIRHVDNHLVVVEKPAGMTTerHPEEKNWPSRrkqlqptldEVLPRLLAKHLGwkipreaagsaaakgrrtqpapklPRIFAVHRLDRDTSGLMVFARTPEASTALIKLFKKHHVTRAYVAVVHGTPVEQKIETYLVRDRGDGLRGSspAGKVAEEAQRAVTHVRLMQTI-----------GPYSVVECRLETGRTHQIRIHLAEAGHMLCGEKVYTHKLGEKSQRDESGAPRQALHAAELGFVHPITSEPLIWRMQLPQELADWI-----------------------------
>UniRef50_A7NF15(77-295:309) Pseudouridine synthase n=2 Tax=Roseiflexus RepID=A7NF15_ROSCS   E=9e-47 s/c=0.86 id=33% cov=80%
---ILYEDADLIALDKPIDTYVEATPWDAEGHLRAALAhfleVRDGSAPPLHLAHRLDRDTSGVLLLSKAPDVNAALQRAFREGAVRKTYLALCAGLPAfDEIEIETGHGRGRGGVFRVFPHEEIGralpqggtVKAMRTRLRVVRRMD-----------DAALACATPLTGRTHQIRLHLAFLGHPLIGDVKYGGPSTWRG----VVVQHHHLHAWRLELPHPRSGTALIIESPAP------------------------------------
>UniRef50_C8PJZ2(77-462:495) Pseudouridine synthase n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PJZ2_9PROT  E=2e-46 s/c=0.49 id=29% cov=86%
-VEILYEDDDLLVVNKPAGLTVHPAASVKEPTLVdwlksRGYLLSTLGGElRAGIVHRLDKLTSGALLVAKNNAAHAALSAQLSDKSMGRIYLALIDLPLKEPCVIERPISRNPaNRLKMGIVPGGRSAKSAfyeilsgaeltelqnsaercdeilgagdgtaanasasristeekilgdamdkistgdankisavstgkdkilnasrdadaskilATHAsanpnagtdkilnnradnvdeisnncmqsadKILIQSADKIPNNRADNADkiltadmsadqtqtarlaenkalnfknpaqnyklppinlksFNLVAAKLFTGRTHQIRVHLSSINRHILGDHLYGFKSENAK------ISRILLHAYLLYFIHPRSGKEVKICAGLPSEFLN-------------------------------
>UniRef50_B8I5R6(76-268:303) Pseudouridine synthase n=2 Tax=Clostridium RepID=B8I5R6_CLOCE   E=2e-46 s/c=0.97 id=30% cov=73%
-FSVVYDDDNLLIVNKETGIPVHPDKNQKEAT--LIDKLQSIYGPNLALCHRLDRNTSGLVIIAKNPATLEVMLEKIKNREIQKYYTCIVSGKMEKKnaELVDYLEKNEKLSRVFINPEKTRNSVQIITRYRILASM-----------NSLNLLEVELVTGRTHQIRAHLAYYGHPIIGDGKYGKNAENK----QYNAKYQLLCASRLTF----------------------------------------------------
>UniRef50_C3XV24(72-329:335) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3XV24_BRAFL  E=4e-46 s/c=0.72 id=33% cov=82%
----LYDEGDIVAIEKPYGVPVHGGPGMGVSIADSLPLLQQALKtDRLYLVHRLDKETTGVMLLAKTDDMARQLHSLFRLRKVIKKYWVLTMGVPsHEEGVVDIPIKElevtaqgrphhrmvcvpeysEETKLIVKKKRKSSDAQIAITNFRVLDS-----------CGSCALVECQPETGVKHQIRSHLSYgLGCPILGDHKYShhsklaPQRLPTGMLERFGIQQpkarylpMHLHARQIVLPGFRDGRSLYFTARLPDFF---------------------------------
>UniRef50_C4R1Q9(105-282:358) Mitochondrial tRNA pseudouridine synthase involved in pseudouridylation of mitochondrial tRNAs n=1 Tax=Pichia pastoris GS115 RepID=C4R1Q9_PICPG  E=4e-46 s/c=1.05 id=34% cov=64%
--EIVYQDDNILVVNKPCGVPVHPTGKYYYNTMT--EIMKNELGvSSLYPCHRLDRLTSGILIIGKTPRAAAKYQTQLKQNSIQKTYIARVDGEFPMGNIVcsDKIVNIDCKRGKENGITE---PKEALTNFQRLAYSTSLNQ---------SIVKCSPKTGRTHQIRIHLRNLGHPIANDPLYG------------------------------------------------------------------------------
>UniRef50_C0QYU1(98-334:345) Pseudouridine synthase n=2 Tax=Brachyspira RepID=C0QYU1_BRAHW   E=6e-46 s/c=0.78 id=24% cov=80%
---IVYDDGDLIIANKPANLPVIPSGKYYHNT--LHTIVKNMLNSNINMLNRIDRETSGCVVLSRSSKSASNFCAMLAGRKVngkqykrnsiKKTYIAVienakdiedkftVEGYMLESG------HEYYRRFQTLHKENVEGSKYSKTSFKTIKRI-----------GDYAVVMARLYTGRMHQIRVHLYSKGFFMVGDKIYGKYGPKvfddfieKGIIPEGFFNRQALHAYSLKFNHPITDEIIKVKAPLPKDLKEL------------------------------
>UniRef50_Q12362(161-346:591) Diaminohydroxyphosphoribosylaminopyrimidine deaminase n=25 Tax=Saccharomycetales RepID=RIB2_YEAST  E=7e-46 s/c=1.00 id=29% cov=65%
-IDIVFEDEDILVIDKPSSIPVHPTGRYRFNTITKM--LERQLGYSVHPCNRLDKPTSGLMFLAKTPLGADRMGDQMKAREVTKEYVARVKGeFPIGIVEVDKPVRSVNPKVALNAVCEmsDENAKHAKTVFQRVSY-----------DGQTSIVKCKPLTGRTHQIRVHLQYLGFPIANDPIY-------------------------------------------------------------------------------
>UniRef50_A0YGE0(15-212:221) Pseudouridine synthase n=1 Tax=marine gamma proteobacterium HTCC2143 RepID=A0YGE0_9GAMM  E=8e-46 s/c=0.93 id=32% cov=76%
-VEILFTDDDLLLVNKPAGLLSVPGRHPANKDCLITRVQRQYADAR--IVHRLDMDTSGIMVLALSADSHRALSQLFAERKIIKEYEANVYGTIIDDhRLIDLPLLCDWPN-RPRQKVDFHHGKNAQTWVERVSQH----------PDGWTRVLLKPVTGRSHQLRVHLAEIGHPILGCEFYAHQRAVSMA------DRLQLHATKLEFCHPNSGETI-------------------------------------------
>UniRef50_Q2GKG0(77-284:297) Pseudouridine synthase n=4 Tax=Anaplasma RepID=Q2GKG0_ANAPZ   E=1e-45 s/c=0.89 id=29% cov=80%
--NIIYKDENIIAINKPAGVNVQGGTKVSISLSDLLNKI--IPGEQLHIVHRLDRDTSGVLIIARGQSIARILSEELRFRRVRKEYIAVTKGVPAfSKGEITMPIYCKKQSG----VGETLIPKEAKTVFSVLQS-----------SKRHAVMLLSPVTGRKHQLRIHLSQFCCPIIGDTKYSKD------TEVQQHNSLHLHAFRTSFQ--LFDREIVIKAPVPEYMIATINEL--------------------------
>UniRef50_A8TF58(104-366:372) Pseudouridine synthase n=1 Tax=Methanococcus voltae A3 RepID=A8TF58_METVO  E=1e-45 s/c=0.70 id=25% cov=87%
-MDIMYEDMDILVVNKPKNMVVHPTKTIKSGTLANAimdyQNHNKSESERFKIrfINRIDMDTTGIVLIAKNSFAHQKIANQFQ-GCMKKEYLAVISGNMDvdnldtnlnnsldtelnnnlNDEKYNLPLnlrlkiyKENNSKFSVIIFDRDTDELIEHTNFEIIKNTKDTKDNKDNKDTeisnNFTLIKASLITGKTHQIRRHLAYLGFSIVGDELY---TNNNELNDNFKNYSLMLHSYKTTFIHPRTNELIELIEEPPKDFKILL-----------------------------
>UniRef50_C1N7S8(37-318:360) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N7S8_9CHLO  E=2e-45 s/c=0.66 id=31% cov=97%
-LTVLYEDEHVLAVDKPPGVMTYPAHRLRGGSVVnrAVHHLRgvtrdgsgggagfgFGAATEPIAVHRLDLETSGVLMLAKDKPSASALQGAFERREARKTYLAVCA-ILEDAANASDESDDDFDFERHPGHRRRERRRRAV-HTRGDAGRE--AREHRFTGKRIvgtALVLARPLTGRTHQVRLHLAHAGLPIVGDALYGYDDALRPASGGFE-GRMALHAWNLAVKHPRTKNTMRLAVDMPADMQALSVGLGLRvegvllgdaaaaaAAAGAAKRTSTSARTGSDG----
>UniRef50_D1N1K3(90-317:321) Pseudouridine synthase n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N1K3_9BACT  E=2e-45 s/c=0.81 id=29% cov=84%
---IAYEDDALLVVDKPGNLCVHPSGPFFKHTLW--HLLSSKYGK-IHLVNRLDRETSGLLVAAKNPKAAAKLGK--PGWPMRKEYLALVFGNFADRIEAYGFLVPDLASVVRKKRRFVAGERPPEGAVRP-ESARTVLLPAR-SGERYSLVRALPETGRLHQIRATLFSLGFPLLGDKLYGPDdgiflkirsnAITAADRERLILLRQALHSAKLAFRHPDTGETVAVESPLPPDFR--------------------------------
>UniRef50_C4FZD3(117-352:353) Pseudouridine synthase n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4FZD3_ABIDE  E=2e-45 s/c=0.78 id=26% cov=85%
---VIYEDRDIIIVNKPVNVLSQIAkTGDVSMNEWLISYLinsgsltaEDMLTVKPAVVNRLDRNTSGIILAGKTLTGLRFLSDIIKTRKLTKYYLTIVKGEIPNNFTAEAYLLKNDNHNTVKIYKDKvEGAEYIKTAYEVLQVKD-----------GHSLLKVELITGKSHQIRAHLSFLGYPVIGDGKYGLKSEN-TNYRRMGLNTQFLHSYEIKFPK-FEGEfaylsERSFSAKLPERLEKVANKLGFN-----------------------
>UniRef50_P59831(14-216:222) Ribosomal large subunit pseudouridine synthase A n=20 Tax=Proteobacteria RepID=RLUA_HAEDU  E=2e-45 s/c=0.91 id=35% cov=77%
-LEEVYRDNHIVVINKPSGLLSVP--GNRPEYYDSVMTRVQQRYGFAEPAHRLDMATSGIILLALSKVAEKELKRQFRDREPKKHYIALLWGKLGDRvgqtGEINFPLICDWENRPRQKICYERGKK-ATTHYEVLEHL----------ANNTTRVKFTPITGRSHQLRVHSLALGHPIIGDKFY------ANPLAKSLAPRLCLHAESLTIAHPISAELMTF-----------------------------------------
>UniRef50_Q9LT72(185-470:477) RNA pseudourine synthase 4, mitochondrial n=2 Tax=rosids RepID=PUS4_ARATH  E=3e-45 s/c=0.64 id=32% cov=65%
---VLYKDPAIIVLNKPHGLAVQGGSGIKTSiDELAASCLKFDKSESPRLVHRLDRDCSGLLVLARTQTAATVLHSIFREKTTgasaygvkknvkslKRKYMALVIGCPPRQrGQISAPLRKVVvdDGKSERITVNDNGElvstQHAITEYRVIES----------SPHGYTWLELRPLTGRKHQLRVHCAEvLGTPIVGDYKYG------------------------------------------------------------------------------
>UniRef50_C1E1G0(27-304:327) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E1G0_9CHLO   E=4e-45 s/c=0.66 id=31% cov=87%
---VLHRDADVLVVDKPAGVPM-RSVHGVKGVDAFLADLRFDLAHPPMTVHRLDRDTTGCLILARTREAQRTLAGYFQDRarvarrgsgrstkttspeslgDVRRVYWALVSAtsTLASRGTIDAALV---TTHAGVTLKPGAGAKPAATDYEVISRASPDSCAPTAAGRVPAVLALVPRTGRKHQLRVHCAgALDAAIVGDYKYGYRDVSRTGGVADDWRRvlrdiderstrrlndagtadgevrgagvpLHLHARCVEFTHPSSGERVRVVAPAPSHMSLACE----------------------------
>UniRef50_Q11Q54(20-242:242) Pseudouridine synthase n=7 Tax=Bacteria RepID=Q11Q54_CYTH3   E=1e-44 s/c=0.82 id=31% cov=82%
-FTVVFEDNHLIAVNKKNGVLVQGdDTGDKPLSELVKEYLKKKYNKpgnvFAGVIHRIDRPVSGLVLLAKTSKALERMNKQFADKKIQKAYL-MVSGskpNPASAKLVHWLTKDAKRNIAKAHTSEVKESKYCELSYSLLTSSD-----------RYFLIEVKPVTGRSHQIRCQMASIGCVIKGDLKYGAPRSNPDG-------GICLHSHKLSFQHPVTGDNMQLKADPPkgEPWNALLKK---------------------------
>UniRef50_B6HIT3(124-321:526) Pc21g01540 protein n=3 Tax=Trichocomaceae RepID=B6HIT3_PENCW   E=2e-44 s/c=0.91 id=32% cov=69%
---IIYEDDDLMVIDKPAGVPVHAAGRYNFNT--VIQILRSERGSEwlPRPCNRLDRLTSGIMFIGKHAKGADKMAAALKARSVQKEYVARVKGKFPDGVVVcDQPIMQVSPKLGLNRVR--ATGKEATTKFRRLAYYppesaketesssdderpATPPASFANETEGYSIVHCLPLTGRTHQIRVHLQFLGHPISNDPIYSNRR---------------------------------------------------------------------------
>UniRef50_A5E2D2(189-357:622) DRAP deaminase n=4 Tax=Saccharomycetaceae RepID=A5E2D2_LODEL   E=2e-44 s/c=1.07 id=30% cov=65%
-IKIVYQDDDLLVIDKPSGIPAHPSGRYRYNSVT--KILQHEMGIVLHPCNRLDRLTSGLMFLGKTAKGSTKLMTQIKDRNVSKEYIARVKGKFPKESiTVDQPLLTLNPRLTLNVVDFVKG-KEASTEFKRISY---------DPKTNTSVIKCHPLTGRTHQIRVHLQYIGYPIANDPIY-------------------------------------------------------------------------------
>UniRef50_D2R6S8(7-224:230) Pseudouridine synthase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R6S8_9PLAN  E=2e-44 s/c=0.83 id=31% cov=80%
-LDILHEDNHLLVINKRPLLATQGvAEGTPSLVTEVQQYLKVKYKKpgnvYVGVVSRLDAHTSGVVVLARTSKAASRLAEQFREQGVEKTYWAAVEAAPEPASgeLVSWVVKDDKNRRMTIADRKLAGCQKAVLTYETLEQ-----------NKSAALVSVKLETGRKHQIRLQLAdELSLPVIGDRKYGSRIEFPEG--------IALHARELAFDHPVGGKRLSFVAPLPATWK--------------------------------
>UniRef50_C5ZYE3(75-302:319) Pseudouridine synthase n=3 Tax=Helicobacter RepID=C5ZYE3_9HELI   E=2e-44 s/c=0.79 id=32% cov=74%
----IYENEDFALFNKPAQMLIHP--KGRFFHHSLMDEVREYFGTEASLIHRIDKETSGLVLVGKHKRSIVELGELFANNRIKKKYLALIKGKMCKTSKIVgdfcllmpLSLQEKGGDLSVRSVflgqnlRKDSkllGFRDAKSEFEILGEF-----------GGNTLLKVYPITGRTHQIRVHLFSLGFPILGDPLYGCedwqsreyldsefIEENRDFglcaekrKEYFGADRLMLHAYSLEF----------------------------------------------------
>UniRef50_A9HEJ0(12-224:227) Pseudouridine synthase n=10 Tax=Acetobacteraceae RepID=A9HEJ0_GLUDA   E=4e-44 s/c=0.85 id=29% cov=82%
-FPVLFRDNRFIVIDKPPGLPVHPGPSGGPSVEDSFPLL-SRRADGPWLAHRLDRDTSGCLLIALRKQALLAAQAAFAAGQVRKTYWAVVQGRPaADSGTVAMTMARHSDRQGWRMV-AAPDGQASRTDWRVLAS-----------DGRESWLELHLLTGRTHQARLHCASLGCPILGDPVYGGAEG----------PTLHLMSRHLAL--PLS-PPVSATAPPPAHIRATLDRHGWQGI---------------------
>UniRef50_C1E9U3(213-540:545) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E9U3_9CHLO   E=4e-44 s/c=0.55 id=29% cov=90%
-LDVIHEDDDVLVVNKPPGLrfhPVHRFEGNSLLSRAIGHVRRsgrdddrldgdaagDGHAHVPHVVHRLDMDTSGVCVLVKRPELVDGFARQFRgdagERRAVKEYLAIgvgaappgVTGcvvkadWKPPEAsgneqttaaefigvefTVDAHVGPHASIPEARAVHRPPptperipkrngsggdpdAPKPARTDVRIVSSSRVPIDVNDDgdvmQSLTAVLARVRLHTGRTHQIRVHMAHADLPILSDPLYGPHIRWDGASPcadastsailppgvdadvwggPRWLGRQALHAARLTLRHPETNEEMTFEARAPEDMRGACVALG-------------------------
>UniRef50_Q25257(511-735:741) ORF C n=5 Tax=Leishmania RepID=Q25257_LEIDO   E=5e-44 s/c=0.80 id=33% cov=80%
IIPVLYEDDDVLVVDKPAGLATsrHGLSCTQLGTpttdLISVLLATDRVGAlargifRQGQVHRLDAETSGCLLIAKSDVAADSLrhqlgtSAAFSHHS--KIYHALC--------VVLEPSLRNVRLHDDIIDAADPKIR---TRYRVIR---------FFPKHRVAWVECRIQQGKKHQIRRHLASRGLPILADLEHGGAVCCQSM-----ISRVALHAHSLSFIHPVTADPITAAAPLPADFRRCLSLL--------------------------
>UniRef50_C7RHG0(84-285:318) Pseudouridine synthase n=4 Tax=Anaerococcus RepID=C7RHG0_ANAPD   E=5e-44 s/c=0.89 id=27% cov=74%
-LDIVYEDNNIIIMDKKSGLLTHSSSKKDYGNNLVDNMLHYLYKTksfdmsdrtfKPAVVNRLDRNTAGLVIGAKNAESLRSLNKAIRENKIDKFYLTIVKGYVEKEFSIDTHISKNDNRNR---VSKSRNGKRIKTNFKPLET-----------NKKFSLLECELITGKTHQIRFSLKENSTPIIGDRKYGDRNTNQKLRK-FGINNQILLAYKIRF----------------------------------------------------
>UniRef50_B3DY53(12-239:268) Pseudouridine synthase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DY53_METI4  E=6e-44 s/c=0.79 id=28% cov=82%
---IVEECQDYLIVDKPPFLLSHPTRKKKGPSILEwLQNLHP--GISFKLIHRLDRETSGLLVVAKNSAAAAYFGRQMEKRLIQKGYLAISWGELKADYLkIEAPLGYLGGAKGNEIVIRQgivPHGTQSVTEIYPLGH-----------GGGYSLLWVRPLTGKLHQIRVHLSTIRHPVVGDKLYGPNPsfflefakrgWTEEMEKVLLLPRHALHAAYLSFF--WKGDKKQFYSPLPEDLKKFL-----------------------------
>UniRef50_A5FWV1(1-172:224) Pseudouridine synthase n=1 Tax=Acidiphilium cryptum JF-5 RepID=A5FWV1_ACICJ  E=6e-44 s/c=1.04 id=32% cov=65%
MIDpvILYHSTHLVVIDKPAGLPSHRGRGGGPSVEDWFPRWR-RGADGPWLVHRLDADTAGCLAIARRKTTLVALQRAFAQRRVGKTYWAIVEGVPaAAHGTIELALARRTVPGGWRVA-PDPRGDPAITDWRCLA-----------AGQGRALLELRPRTGRTHQLRVHCAESGFPIVGDPLYG------------------------------------------------------------------------------
>UniRef50_Q5M721(97-369:369) RNA pseudourine synthase 5 n=13 Tax=Embryophyta RepID=PUS5_ARATH   E=7e-44 s/c=0.66 id=33% cov=83%
-LEVLYEDDDLIALNKPSGLQVLPGGLFQQRTVLTQLqwcfgkndsYIGSRESPHPVPVHRLGRGTSGILLCAKTKLAKTKLAAYFAEgtslvgsgnldqecgtgRKLSKIYRALADGIVEEdEVVIKQPIGvVRYPGVAQGLYVASPEGKPAFSKVFVLE---------RDREKNCSLVKVEIQSGRPHQIRIHLAYMGHPLVGDPLYvaGGQPKcfdpdlvddAAAFAEDGGYRRpnqavpgdcgYHLHAHQVELPNLLnTHKVVKIVAPLPP-----------------------------------
>UniRef50_Q5HN86(75-270:274) Ribosomal large subunit pseudouridine synthase, RluD subfamily n=61 Tax=Staphylococcus RepID=Q5HN86_STAEQ  E=8e-44 s/c=0.91 id=29% cov=75%
---IYYEDDDLAIVMKPKGVKTHPNDLKESNTLMN-HVIYTVDSEYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEYNEITRIYKANVKALLPiKPQTIDMPIGKDKFHSNKR--RISNTGQRAITH----------IINSKMIKEGVCQLDIKLDTGRTHQIRVHLAEIGHPVIGDPLYGTST----------LRQLELNSHQIEFTHPLTQEIISV-----------------------------------------
>UniRef50_UPI0001BC3376(6-218:222) putative 23S rRNA pseudouridine synthase n=1 Tax=Butyrivibrio crossotus DSM 2876 RepID=UPI0001BC3376  E=1e-43 s/c=0.84 id=28% cov=79%
---IVYEDDNIIVCNKPVGMPSQSDRTFEQDLVSYVLTHRTEQNEPAYaaIINRLDKPVGGLVLFAKNKKAAAGLSAVSGEHGIEKNYYALVKGSPCDKGEfTDYLLKDGKNNISTVTDKDTKGSKKAVLLYEKLGEKTI-------DGEKYSLMRVRLLTGRHHQIRVQFSHHGYPLYGDIKYNSDFRNRRDVSP------ALFAYHLSFKNPVGADRITVEA---------------------------------------
>UniRef50_B8BQ07(21-243:246) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BQ07_THAPS  E=2e-43 s/c=0.80 id=29% cov=80%
-IRVLYSDDDIVVIDKPANLRSVPGHASNSPDADDGSKSKYQ----LHVVHRLDCQTSGIMVVARNSTAASKLCHAWRERDiVQKTYLAYCQRWPPyhdeqlSEGTIDLPLAASRTERIKWEVRAlEDGGKP----------LKSELTVERDNDNGVVL-ELKPITGRTHQLRIHCATIGSGIVGDSLYGDSPVEWFGDKpqhgqqtisQSDTQTLRLHAHKLVFPHPSTGSEVTFVSP--------------------------------------
>UniRef50_A8SS78(8-222:238) Putative uncharacterized protein n=5 Tax=Clostridiales RepID=A8SS78_9FIRM  E=2e-43 s/c=0.83 id=28% cov=80%
-LNILHEDSDIIVAVKPCGVPTQPDKTNSESMVSMLKlriYERENRKEEPYLVpiHRLDRPVGGVMVFAKTPEAAAALSKQSEDGTMLKYYQAILTGELPNDQGVlkDYLLHDTKDNVTKTVDKDTPGAKYSELEYEVLDVMDTDEGV-------LSYVLVELITGRHHQIRAQFAKRKCGIWGDTKYNPKFQKTKKKYKEIG----LHASRLEFDHPTTGEHMVFK----------------------------------------
>UniRef50_B0G9B7(24-244:249) Pseudouridine synthase n=2 Tax=Clostridiales RepID=B0G9B7_9FIRM   E=2e-43 s/c=0.81 id=27% cov=81%
-INILYEDTQILVCVKPAGVATQ---SKRIGSPDMVSLLKNHISmtsgksgePYLAVIHRLDQPVSGILVFAKTPAAAKDLNRQLTTSGFGKHYYALVAGTPePTSADLENFLVKDARTNTSRIcQKGTADAKLAKLHYDLVDTTFFADIASSIPVAT-SQLKIKLDTGRHHQIRVQLSGMGCPIIGDTKYNPDSPKLTARRTP----LCLCAYQLEFRHPVTKKAMTF-----------------------------------------
>UniRef50_Q0CVH8(108-308:507) DRAP deaminase n=1 Tax=Aspergillus terreus NIH2624 RepID=Q0CVH8_ASPTN  E=2e-43 s/c=0.88 id=30% cov=69%
---IIHEDDDLLVIDKPAGVPVHAAG--RYHYNSIIEILRNENGVEwmPRPCNRLDRLTSGVMFIGKTAKGAEKMCAKLQQRTVQKEYIARVKGRFPDGVVIcDQPIMQVSPKLGLNRVR--ATGKDAKTKFRRIayyppaapaageedsqgegeERAATPPPALANEDEGYSIVHCLPLTGRTHQIRVHLQFLGHPITNDPIYSNRR---------------------------------------------------------------------------
>UniRef50_A8EQU7(78-280:300) Pseudouridine synthase n=2 Tax=Proteobacteria RepID=A8EQU7_ARCB4   E=3e-43 s/c=0.87 id=28% cov=73%
--------EDFAIFDKPTNLMVHP--ISKNTSYSLLDEIRYHFGENANLIHRIDAETSGLVIVGKNKKSEIELKDMFQEKKYHKSYLAIVQGEIKEELKINKALDREGKAIGVRMKVctQEEGGKESITIIKPIIYDK---------EKNLTLVEALPLTGRQHQIRVHLHSMGHTILGDPIYGVDDEnaenylNKTLSEEDRFKvtksyRLWLHANYLEF----------------------------------------------------
>UniRef50_A4S7H5(47-310:318) Predicted protein n=2 Tax=Ostreococcus RepID=A4S7H5_OSTLU   E=4e-43 s/c=0.67 id=29% cov=85%
----VYVDDDVYVLNKPAQTYVHdierlveRGMVKCDDatTVDNRATTRDvpfNASESARVVHRLDRDTSGCLVVARNRDAIRSLSAQFADGTVQKTYVALCAATADYDGVEDHrrvftgwgrakyglfrlydaaDIGRALPGNKKVKVKHAETtiiVERVITDGVALRFCEPPTADDaDRRRHRVALARCSPLTGRTHQIRLHCASLGLPLVGDVRYGGPiaaTRDGPIDAPFSARRVAgalLHAERVAFRHPKSNLRVDVHAPRPP-----------------------------------
>UniRef50_B0ME87(84-322:329) Pseudouridine synthase n=1 Tax=Anaerostipes caccae DSM 14662 RepID=B0ME87_9FIRM  E=6e-43 s/c=0.74 id=28% cov=76%
-LSVIYQDSNVLIINKPYGMLSQKAkPSDISVNELIVPYClehgilkeSDLELVRPSVCNRLDRNTTGLLIAGISLEGLQTMAEVLRDRSVRKYYYCIVKGMVNKKTRISGYICKDHRENKVSFSeRKISGGSRIETAYEPMA-----------AGHGFTLLRVELITGKTHQIRAHLAGMGFPLAGDTKYGDRGVNLQMKQKFGVKHQLLHCGCLEF----------------------------------------------------
>UniRef50_C7H0C0(83-273:322) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7H0C0_9FIRM  E=7e-43 s/c=0.92 id=29% cov=68%
-FKIIFEDDNLLVVYKRAGLLTHGSSTEKKRTLLNeVKTYLIQKGEYdpgfektfsLATSNRLDRNTEGLIAIAKNAASQRELNAAFKEGRIERYYVAEVVGEVRGDVTIDYPLYKSAKNntvFADKDGSVPPDVtKEAITKVHPIRVNRIDKNGSEF---TYTVVRVKLLTGRTHQIRVHLAAIGHPLVNDRKY-------------------------------------------------------------------------------
>UniRef50_A8RLV7(1-243:274) Putative uncharacterized protein n=4 Tax=Clostridiales RepID=A8RLV7_9CLOT  E=8e-43 s/c=0.72 id=27% cov=83%
MVPILYEDKDIIVVQKPAGLESQVSRGfAPDMVSEIRRYLHNPqdihnhpqgvstaQPPYVGVIHRLDKPVEGIMVYALNQKSAASLSAALQAGKIKKSYLAVVCGKPVDKQgtYVDYLRHCKENNTSKIVDKSDENSKKAVLNYRVLEVINNP----KNQEQILSLIDIELLTGRHHQIRVQFAGHATPLYGDERYGGGLSTKSTTMTVDRGRkkssfgdahrpLALCARRLAFPHPSTGKIMEF-----------------------------------------
>UniRef50_Q7XA65(76-316:322) RNA pseudourine synthase 1 n=12 Tax=Magnoliophyta RepID=PUS1_ARATH   E=2e-42 s/c=0.73 id=30% cov=82%
--DILYEDEYLMAVNKPKG--VYCEAVLRSAPQIVLDSSSEY-----HLANRLDRDTSGVMIITKSHKVAAKLVKAFTEHKIRKSYIALCIGSSPnwRRVTVSSGHGRSKHGAWRVYAALDVGrvlpggsfVRDMETTFEVVSVNSVKNESCELEDVNHVIVaegerelscggddddvvvvvRAFPRSGRTHQIRLHCQYLGIPIRGDVKYHGVYEWNGRT----FEGHELHAECLSLDHPVTGDSIVIRAPLP------------------------------------
>UniRef50_Q96CM3(99-365:377) RNA pseudouridylate synthase domain-containing protein 4 n=19 Tax=Amniota RepID=RUSD4_HUMAN  E=2e-42 s/c=0.65 id=33% cov=88%
---ILHQDKNLVVINKPYGLPVHGGPGvqlcITDVLPILAKMLHGHKAEPLHLCHRLDKETTGVMVLAWDKDMAHQVQELFRTRQVVKKYWAItVHVPMPSAGVVDIPIVEkeaqgqqqhhkmtlspsyRMDDGKMVKVRRSRNAQVAVTQYQVLSSTLSS-----------ALVELQPITGIKHQLRVHLSFgLDCPILGDHKYsdwnrlapqklsvGTLKKLGLEQSKARYIPLHLHARQLILPALGSGkEELNLVCKLPRFFVHSLHRL--RLEMPNEDQ---------------
>UniRef50_Q1N0K9(3-182:223) Pseudouridine synthase n=1 Tax=Bermanella marisrubri RepID=Q1N0K9_9GAMM  E=3e-42 s/c=0.97 id=35% cov=70%
-IDIVYEHQDWILVNKPEGVDFH----SQNGEVGFHRQLCDQLGFNVFPVHRLDKATSGLLLFAKSQDACRGLVELFSQRKVEKYYLAIVSNK----------LKKKQGKVFGDMVKSRNGSYK-LTQERRNPAFTQFLSQALKPGYRLAL--LKPKTGKTHQLRVAMKSLGSAIVGDQRYGGESAN----------RLYLHAYALKF----------------------------------------------------
>UniRef50_B4Q9B3(192-358:555) GD22253 n=7 Tax=Neoptera RepID=B4Q9B3_DROSI   E=5e-42 s/c=1.04 id=30% cov=65%
-IKIVHMDEDIVVVNKPASIPVHPCGRYRHNTVVFILAKEFNL-KNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEGVFPD-GIVECKEPIEVVSYKIGVCKVSPKGKDCTTTFQKLSQ-----------NGTTSVVLCKPLTGRMHQIRVHLQYLGYPILNDPLY-------------------------------------------------------------------------------
>UniRef50_Q1IZY6(16-247:251) Pseudouridine synthase n=3 Tax=Deinococcus RepID=Q1IZY6_DEIGD   E=9e-42 s/c=0.74 id=31% cov=82%
---VLVEHPDFYVVHKPALWLTHPVRARVDVPDVLSYMRAETGEPDLAPPHRLDRETSGTQLLSRDPDAARRFFTLFKTHLVGKTYLAVVHGSPDwERYTLDAPLGDLGLGGANRVIIRQavvPDGRPAVTDFRVVEQ-----------RGGFTLIEAYPRSGRLHQIRAHLSHLGLPLVGDKIYGPDPQAFLDFMHHGqtlelterllLPRQALHAARIAF--PWAGAQFAAEAPLAPDLR--------------------------------
>UniRef50_C0NWM0(125-346:545) DRAP deaminase n=10 Tax=Onygenales RepID=C0NWM0_AJECG   E=9e-42 s/c=0.77 id=28% cov=70%
-ISIIHEDDDMIVIDKPAGVPVHPAGRYNYNSILEIMKAERGNGWVPYPCNRLDRLTSGVMFIGKHPKGAEQIGEKLRSRTVRKEYVARVKGKFPDGVVLcDQPMLKISPILGLNRAR--ASGKEARTKFRRIAYYPPHKQAGKKQGlsagpatppatlpdqmnisdsqtdtptgaaipvpmspdeEGYSIVHCLPLTGRTHQLRVHLQYLGHPITNDPIYSNRR---------------------------------------------------------------------------
>UniRef50_UPI000185C0B7(98-322:342) 23S RNA-specific pseudouridylate synthase n=1 Tax=Corynebacterium amycolatum SK46 RepID=UPI000185C0B7  E=2e-41 s/c=0.76 id=30% cov=83%
-MPIVFQDDNLVVVDKPSFLATMPRGRHITETAVV-RLRRELGNPELVPAHRLDRLTSGLLIFTARREVRGAYQGLFASGEVTKRYHALTSPTPIAGGASEAlpetPLelrTRQHKIAGQMQAYTLEGEPNAHTIIEHISLVDVPSDADGlaADSGRVALWQLKPITGRTHQLRLHLSELGFPILGDQYY---PEILPLEAENTSEPLHLVCVEMSFADPVTGEQRTFHS---------------------------------------
>UniRef50_Q9VKU8(216-382:547) RluA-2 n=6 Tax=Sophophora RepID=Q9VKU8_DROME   E=2e-41 s/c=1.02 id=30% cov=65%
-IKIVYMDKDIVVVNKPASIPVHPCGRYRHNTVVFILAKEHNL-KNLRTIHRLDRLTSGLLLFGRTAEKARELELQIRTRQVQKEYVCRVEGRFPD-GIVECNEKIDVVSYKIGVCKVSPKGKDCKTTFKRIGEVGSD-----------SIVLCKPLTGRMHQIRVHLQFLGYPISNDPLY-------------------------------------------------------------------------------
>UniRef50_A2R658(127-290:484) Similarity: patentmatch against protein AC A46560_1 Trembl n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2R658_ASPNC  E=2e-41 s/c=1.04 id=31% cov=62%
---IIHEDDDLIVIDKPAGVPVHSAG--RYHYNSVLEIMRSQRHPEwvPRPCNRLDRLTSGVMFLGKTAKAAENMTGKLKARTLQKEYVARVKGKFPDGVIVcDQPIMSVSPKVGLNRVR--ATGKEAKTKFRRL-----------------AIVHCLPLTGRTHQIRVHLQFLGHPISNDPIYSNRK---------------------------------------------------------------------------
>UniRef50_D1B3J6(56-240:242) Pseudouridine synthase n=3 Tax=Campylobacterales RepID=D1B3J6_SULD5   E=2e-41 s/c=0.92 id=30% cov=65%
-IKVLFEDEYIMAVDKPAFI-------TSEEVAEI---------KKLPLLHRLDRETSGVLLLTKDDEFRQKAVNAFKKREVHKEYIAIVEGKVVEATEVNAPIL-TIKKGNTAYSKISPDGKEAISYIEPL-----------MIEGKRSKIKVTIETGRTHQIRVHLKSIGASILGDTEYGGRPH----------KRLMLHASKI------------------------------------------------------
>UniRef50_Q11NL4(11-217:223) Pseudouridine synthase n=2 Tax=Bacteria RepID=Q11NL4_CYTH3   E=3e-41 s/c=0.83 id=28% cov=77%
---ILYEDNYILVVNKPCSLMVEP---DRNGHPNLLQQVQKYVKKSLHPnkevyvqhIHRLDRPVSGIVLFAKKKSMLKELSEQFAQRTVKKYYQALTRKVTTNgKGALNHWHFKDSKNKKAILYKEEQQETSAVS---------LGYSTSDY-NADYTLWDIQLNTGKYHQIRAQLSFEGYPILGDECY-------KSTDVYAPNAIALHACKLEFVHPVSKESMRLEA---------------------------------------
>UniRef50_Q0IBH1(25-218:220) Pseudouridine synthase n=11 Tax=Cyanobacteria RepID=Q0IBH1_SYNS3   E=3e-41 s/c=0.88 id=34% cov=74%
----------FLVVEKPSGLLSQPGLGDsqSDSLITRLQAVR----PELRLVHRLDRDTSGLLLLARDPESLKVLGGLFAERKVHKFYAADVHGHPKsRSGAVRLPLARLSAHPPRYGPRRD--GRSCLTLWR--------CAQMGSDRSRLWLA---PRTGRSHQLRAHLAAIGLPIIGDPIYASSGLGSPG------ERLHLHALGLSFSDPFSGQRIRVRSSLP------------------------------------
>UniRef50_B8LRV2(63-357:358) Putative uncharacterized protein n=1 Tax=Picea sitchensis RepID=B8LRV2_PICSI  E=4e-41 s/c=0.58 id=28% cov=87%
--EFIYEDEWMIAVNKPSGVYCeHVLSSIPEllaSSPSSAGAANDVNPLELHLANRLDRDTSGVMVITKLHKIAGQLVKAFTDRKVRKTYLALCIGPAPKwnNIYIESGHGRSKFGAWRVYSRTDVGrilpggtvVREMATHLKVLAvnanhrmhrdsvdkaqnssqgiafdlkedrfatvgdngstdsiekvvvTEQNSKAPGQDRDIVSSpnirkndevLIRASPLSGRTHQIRLHCQYMGLPIRGDVKYEGPHIWKGITYA----NHALHAESLCFEHPVTNNMVKFHAPLPQWVMEA------------------------------
>UniRef50_Q74Z98(105-288:381) AGR305Wp n=2 Tax=Saccharomycetaceae RepID=Q74Z98_ASHGO   E=4e-41 s/c=0.92 id=29% cov=65%
-LKVVFEDNDLLVIDKPCGIPIHPTAYFYKNTLT--EVLEDARGYPLFPCYRLDKITSGLLIFAKTQQTASRLQSQIRDQNMNKWYLARVDGNFDfNKKTASSPIYTFEPKKSLKGAFAP--VRDALTEFYHVAYNEELNQ---------SLVLCKPLTGRTHQIRIHLARLGHPIVNDPFY-------------------------------------------------------------------------------
>UniRef50_UPI0001C37945(84-309:315) pseudouridine synthase n=1 Tax=Ruminococcus flavefaciens FD-1 RepID=UPI0001C37945  E=5e-41 s/c=0.75 id=27% cov=81%
-LDTVYEDENVIIVNKPLGLDSHSNGEHNDDTLINRiklylynkneYQPDEESSFAPALCSRLDRNTSGLVTAVKNAAALREINSAIRDGMVHKIYLCITIAQPPKSADIITAYHKKEDSRNIVRISDHPldGYKPIKTGYEVLKSHK-----------GLSLVKVTLFTGRTHQIRAHLSHVGAPLLGDGKYGDTSVNK----RYGVFYQALCAYGLEFALSEDSplaylNKLDIHAPEPD-----------------------------------
>UniRef50_UPI00015B45C3(20-222:272) PREDICTED: similar to conserved hypothetical protein n=1 Tax=Nasonia vitripennis RepID=UPI00015B45C3  E=7e-41 s/c=0.83 id=32% cov=74%
-IEILHQSDNFLIVNKPYDMVI--NSNNPSVKSVQLiiremfpNLVNPNLYHEFYFVHRLDYATSGVMCLALNKQSAQAASSAFEERTVRKYYLALVHGHIDKySMVIDIPIGhdvRELNGNRKMCTKDDDFCEKARKSCTALLVLEKGYIDDRPVTK----VLLYPKTGRRHQLRVHCAHIGHIIVGDYTYSGKTDTKP-------HRTFLHAFRL------------------------------------------------------
>UniRef50_C7H1V6(1-220:253) Pseudouridine synthase, RluD n=1 Tax=Faecalibacterium prausnitzii A2-165 RepID=C7H1V6_9FIRM  E=9e-41 s/c=0.77 id=30% cov=75%
-MNILYEDTALVVLDKPAGL------TSEEGVPAALRQRWGRPDAYVGVIHRLDTGVSGLMVYARTPGAAAALTKQvtesqqayaILDGRVEagpgapaqpcflKTYRAVIAGGPdeqlPPEGILRDYLFKDSRKGRvFPVKRPRKGVREAVLEYRIVETA---------PDGSLSLAEITLHTGRTHQIRVQFASRKHPLYGDGKYGSRFKGD----------IALQSAGLQFVHPETGEKMAFQ----------------------------------------
>UniRef50_B0D7R4(31-268:321) Predicted protein n=1 Tax=Laccaria bicolor S238N-H82 RepID=B0D7R4_LACBS  E=1e-40 s/c=0.71 id=31% cov=84%
----LYVDPAVAVVTKPHGLVCqliHRqlPAGRVNHFNVMMQDLKAHLSleTFPYPVHRLDKSTTGAFLLALTESSARQLSQQFQKRTVQKTYLALVRGgeksFPEKFGEIRTTLNKVDGYPE---VDLSSQGQPCATDWKLLAS---------SPIAPISLLELNLLTGYKHQLRVHLAKcLHAPILGDAQYSKKPLSSAITDVVKIPedRIFLHASEISFLKykssgPHKQFRLAVRAPLPREFLKLCKDL--------------------------
>UniRef50_C5DCE4(115-293:397) KLTH0B02376p n=2 Tax=Saccharomycetaceae RepID=C5DCE4_LACTC   E=1e-40 s/c=0.94 id=33% cov=63%
---VVHECEDLLVIDKPSGIPIHPTGQYYQNTLV---EVLKSHGKTVFPSHRLDKITSGVLILTKNPHMANKIQHQIRQRTMSKIYLARVDGAFPmadtlgsltpfespdKTQTVDSAIYTVELKKQFPAAFSP--PREAKTKFYPLKY---------YPKSDETLVACQPITGRTHQIRIHLARLGHPIVNDPFY-------------------------------------------------------------------------------
>UniRef50_D1AMK0(88-269:285) Pseudouridine synthase, RluA family n=1 Tax=Sebaldella termitidis ATCC 33386 RepID=D1AMK0_SEBTE  E=1e-40 s/c=0.92 id=30% cov=70%
---VFFEDDDCLIINKPGGVAVHKGTGNQYGLAEVYKSI--YKNENLNFANRIDKETKGLLLGAKNLKFLRYLTEKIRNNELEKRYIAVVSGIITEDEfTIDNFLETKENKV---VVSDKENGKAAKAVFKKIKTIK----------NKYTVLEVELITGRKHQIRVQLADMGFPIAGDKKYGSR--NTRGE-------LMLLAYYLKF----------------------------------------------------
>UniRef50_A4S075(100-327:334) Predicted protein n=2 Tax=Ostreococcus RepID=A4S075_OSTLU   E=2e-40 s/c=0.74 id=31% cov=80%
---VVLRDSDgIAAVVKPAGVLTHPVEGGGSELTLMDAALSRFDGQlsdlngldKRGIVSRLDKPTSGVVLLAKNNASHAELLTQFYQRCVVKQYCALLDGTLPASGSESTPL----------------DGRSATSEYEVMETFIG-------PSWSYSLVRVEPKSGRKHQIRRHMALLGAPLVGDPLYRTARTKQINPNPPECVLKAlsvgkpgtifwLHASAVEYSGMPNGERIVVSAPLPSAFETLLA----------------------------
>UniRef50_A4XK98(79-268:311) Pseudouridine synthase n=2 Tax=Clostridia RepID=A4XK98_CALS8   E=2e-40 s/c=0.88 id=28% cov=72%
----VYEDDNIIVIDKPYGIPSHP---DTNNEYSVVNWIEDNYSGNqlPALCHRLDRNTSGLMIIAKNRQVLNEMLKYMSRRAIKKKYLCITKKVdLPKSGVLVHYLKKDSKKSKVYISDlPAEGYSEIVTRYKIIR-----------GKDDLLLVDVEIETGKTHQIRSQLAHVGLCILGDSKYGDWALNKKYNASI----QCLCAYYLKF----------------------------------------------------
>UniRef50_B6JZY3(105-276:401) DRAP deaminase n=1 Tax=Schizosaccharomyces japonicus yFS275 RepID=B6JZY3_SCHJY  E=2e-40 s/c=0.98 id=29% cov=66%
-VRIVHEDEEYVVIDKPAGIPVHPT-GRYNHNTVLHILMHENKCPLLYPCNRLDRLTSGLMFFSKTPKGAERMRVHMISKDLQKEYVARVVGEFPAEKTItcDAKLLTVAPTLGLNRVHPD--GKDAVTIFKRLA-----------FDGHTSLVHCKPLTGRTHQIRVHLQYLGYPIANDPIYANLR---------------------------------------------------------------------------
>UniRef50_C4G2Q7(5-224:236) Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4G2Q7_ABIDE  E=2e-40 s/c=0.76 id=30% cov=77%
-IPILYEDEDIIVCVKPVGILSQ---GDKDGNKDLVRELKKHLvisarknkqsiGKEPYIavVHRLDRNVRGIMVYAKTGRAAAGLSKQIAENKLTKRYMAVVSFTPErctpeinvEKKRIDYIAADKVKNISTIAEKESKGAERAELNYKVIKTA-----------GNKALVQVDLITGRHHQIRLQLSQIFNGIVGDTKYNDDYKLTDGWKDP-----ALEAVELSFVHPVSGEKLSF-----------------------------------------
>UniRef50_B7PYG1(184-441:443) Ribosomal pseudouridine synthase, putative n=1 Tax=Ixodes scapularis RepID=B7PYG1_IXOSC  E=3e-40 s/c=0.65 id=35% cov=85%
---VLYNDNDILVLNKPYGMLCHgPAPGVSDACVLtkllpdLSSALYPRQDAKLYTVHRLDRDVTGVLLLARTQRMADMLNSLFQKHQVSKTYLAITAGVPDHlEGVIDMPLAEGEVEGAKRMVLNPKLDPEfqrlvpkfrksfaAVTTYRVLAS-----------CGRAGYLELRPTTGVKHQLRAHLgLGLRCPILGDHKYSHLRRLAPQKlpgdmlDRLGIRQskvrdapLHLHARAVVVPEILDGRNLTVAAEVPYHFAKNLRRL--------------------------
>UniRef50_C3PKB5(127-344:353) Pseudouridine synthase n=7 Tax=Corynebacterium RepID=C3PKB5_CORA7   E=3e-40 s/c=0.77 id=25% cov=84%
-IPILFEDEHLLVVDKPPFMATMPRARHITETATV-RLRRKTGNNELSPAHRLDRLTSGILVFTKDRSVRGAYQTLFAERRVTKTYEAIAPLADVSPGTVWR--SRMEKTPGELQGRIVEGEVNAITEVAAVEPIDkAPYESIHGSLPELAKYTLKPQTGKTHQLRLHMLQAGVPIIGDPIY--PVIFPAEAEDMRIP-MHLTATHISFVDPLTARPREFFSQLP------------------------------------
>UniRef50_Q09709(107-276:394) Uncharacterized protein C18B11.02c n=1 Tax=Schizosaccharomyces pombe RepID=YA32_SCHPO  E=3e-40 s/c=0.98 id=28% cov=65%
---IVHEDESYVVIDKPAGVPVHPTGRYNHNTVLHILMKENKCSL-LYPCNRLDRLTSGLMFFSKSPKAAEEMRVHMISKSLKKEYVARVIGEFPNSGEVicDAPLLTVAPTLGLNRIHPD--GKEASTVFKRIA-----------FDGHTSLVLCKPLTGRTHQLRVHLQYLGYPIANDPIYANKR---------------------------------------------------------------------------
>UniRef50_D1BPK0(129-372:372) Pseudouridine synthase n=3 Tax=Veillonella RepID=D1BPK0_VEIPT   E=4e-40 s/c=0.68 id=29% cov=80%
-LSVLYEDEDLFIVDKPSGVTVNSKDRLSLANGVAHYFKEHGIKRKVRFLNRLDRDTTGCIVIAKSGLAQSLYQQQMDDNTFEKWYMATVEGIVeADEDTLVFPMERSADGI---HYEVNAKGKETRTDFSVLCRhssqpvdnsvnksensvdiglknvdielvdvdknnLNVDKTVYKSNKCGYTEVLVRLYTGKTHQIRVAFSHIGHPLVGDTLYGAQPTGQPFQ---------LRAQKVVFTHIRTGEHITVMA---------------------------------------
>UniRef50_P72970(61-276:291) Uncharacterized RNA pseudouridine synthase slr1592 n=1 Tax=Synechocystis sp. PCC 6803 RepID=Y1592_SYNY3  E=4e-40 s/c=0.77 id=30% cov=82%
-LSVLHRDEDLWAIDKPSGLPVLPG-GDFVYHTVLEQLKIQYPQESLFPLHRLGTGTSGLLLLGRSTLGRRELSRQFREHICRKIYRT-VIGPcdLPEKFECHQAIGKIPYPQLGYIYAASSHGKPAQSYGRILAR-----------SPEKTWLEVEIRTGRPHQIRIHLASLGYPLLGDRLYGPGGvPINCRTARPSDGGYTLHSYQLGFLHLHTQQAIKLTAPLPPEL---------------------------------
>UniRef50_UPI000050FD43(98-326:332) ribosomal pseudouridine synthase n=1 Tax=Brevibacterium linens BL2 RepID=UPI000050FD43  E=5e-40 s/c=0.73 id=28% cov=83%
-ISVVFEDDDLLVVDKPHFLASTPN-GRFVRECVVTRARLDFDQPDLVAIHRLDRVTAGLLILSKRPETRGRYQRLFQDRLVTKTYRALAA---MPPADLELPLVKESRLVKPRGGRqvlEVEGEPNAFSKISLLGERTPPsprWSDATEPPPRRSVGECpsigeyqlEPLTGKTHQLRVHMNSLGLPILGDPVY---PVDRAPDPYDFSSPLQLLAASIGFDDPLTGRPRRFESGL-------------------------------------
>UniRef50_D0RNQ1(95-287:288) Pseudouridine synthase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RNQ1_9RICK  E=5e-40 s/c=0.87 id=22% cov=75%
----VFECEDYCVLNKPYGYASQDGSKVKLSVIDILNSTKKNY----YIVHRLDKDTSGLMLLAKNRFYAKKFSEMFKSREVKKKYLVIINGK----------IKKNKGEIHSKEKVNGKEI-ESKLYFEVISK-----------KNNFSYLEIDLITGRKHQIRKQFSDIGHPVVGDLKYGDKKNN---------TQLCLLSYEIEFE--YNNKIKKYKATIPDNFKTCLEKF--------------------------
>UniRef50_C6CYJ1(10-218:242) Pseudouridine synthase n=11 Tax=Firmicutes RepID=C6CYJ1_PAESJ   E=7e-40 s/c=0.79 id=25% cov=76%
-IPVLYEDNHIIAVVKLPGIPSQEDeTGDPDMLTLIKQDLKirhnKPGNVFLGLIHRLDRPVGGAMLFAKTSKAASRLSEAVRSRTFGKTYVCVVHGKPAKQQdRLRHYIRKDAKRNQVTVYKEPaADAKEAILEYRVCAQA-----------GGYSLIAVKLHTGRPHQIRAQMAYIGCPLVADRKYGAPNTASVTD-------IALWSTSVEAPHPVTKE---------------------------------------------
>UniRef50_Q8IZ73(228-389:545) RNA pseudouridylate synthase domain-containing protein 2 n=20 Tax=Euteleostomi RepID=RUSD2_HUMAN  E=7e-40 s/c=1.02 id=31% cov=62%
------ENEDVVVVDKPSSIPVHPCGRFRHNTVIFILGKEHQLKE-LHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEKEYVCRVEGeFPTEEVTCKEPILVVSYKVG--VCRVDPRGKPCETVFQRLSY-----------NGQSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIY-------------------------------------------------------------------------------
>UniRef50_A9SET3(56-309:327) Predicted protein n=2 Tax=Physcomitrella patens subsp. patens RepID=A9SET3_PHYPA  E=1e-39 s/c=0.65 id=25% cov=82%
---VLFEDEWLIIVNKPRGLY----SGHVFETMPSLCSSSGETPLHLHMANRLDRDTSGIMIITKCKVAAANLTRSYMNRKVHKTYIAQCAQSQPtwRKSRIESGHGRSRygawhvyakHDIGRRLPVKTETVREMITRLEIVSGPDSLRWDNELSvehdclevivgsedevrlvsnevtkrcsdvDEEVTLVRAFPETGRTHQIRLHCQYLGLPLCGDVKYGG----PLFWQSVHYDSHTLHAESLALRHPMTNQLLQVVAPYP------------------------------------
>UniRef50_C1E6N6(133-363:363) Pseudouridine synthase n=2 Tax=Micromonas RepID=C1E6N6_9CHLO   E=1e-39 s/c=0.71 id=27% cov=84%
----VHEDADYAVVNKPwcVRLDTPRGWPGkvrftpkYPGDLSVEDWLERRYPDWdtVRFCHQLDNATSGVLVAASNKRAAGAAAKLFRERRARKTYLAIVFGHPEQDEwTVDVPMGRDPDDPKGFRERVDPEhGKACETRFRVLKRGRL-NLRGKFEGVPVSKVEVTPVTGRRHQIRLHLQFSGHPIVGDNAY---------SQDTDSFRTFLHAHKLTLPFDEPRGTMQFVAPEPESFAAAME----------------------------
>UniRef50_C1ZMD6(201-393:400) Pseudouridine synthase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZMD6_PLALI  E=1e-39 s/c=0.85 id=30% cov=69%
---------------------------------------------HVRAAHRLDRQTSGLVVLSRVPEAGAKLYAQFQAHDVLREYEALVWGWIEPQRLESELIRDRGDGRRGSRQPVTmleagaedspaanplPAGKMAATN--LVASRQGHFKSGTGELAPVSWIRCQLETGRTHQVRIHLSEKGNPIVGDDVYGTHSLD-------GVPRLYLHAARLGFIHPMTGKRLEFSLSWPEVDRKWLE----------------------------
>UniRef50_A9V182(13-287:289) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V182_MONBE   E=2e-39 s/c=0.60 id=29% cov=90%
---VIYEDNHLVALNKWRGLAVQDAAGSPSTVLSNVDVFqQNKDGFVPRLAHRLDQNTTGVLVLAKTAEAVLRLNRLFQLGAVAKTYEAVLAGQVTKPTGTLKGIPELITEEEDANSeltsnqplfktSASWSHSTAQSHYTVLASAQVNDGRPSRTKPWLTRVELRPTTGYKHQLRIQCADgLRAPVLGDKRYGGGQEQVSPIILQHLQRhglrtaahpyglvMHLHAKQLVIPgYNWDGSDLVLRATLPDHMQLTIDACG-------------------------
>UniRef50_B8BWY4(2-174:175) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BWY4_THAPS  E=2e-39 s/c=0.95 id=38% cov=58%
------------------------------------------------VVHRLDRDTSGVFLLARNDEALKTLHDDFKDKTrgrVTKRYVALVCGHwnsdnascvadrmTTDEGEIDLPLVRDIENPPfMRVATTGNEIKLPVTR-----------------------VELQPITGRTHQLRVHCAAMGYPIVGDSIYGYGGE---GSPREGIEMdedeclLCLHAQRLTIFHPLTKAPMMFECSPP------------------------------------
>UniRef50_B5JQE8(3-192:194) RNA pseudouridine synthase family n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JQE8_9BACT  E=3e-39 s/c=0.86 id=33% cov=72%
------------------------SEGGGDREVDLEQAVSELMGRQCWCCHRLDRLTSGVVVLRKGRRFVKELAGQFESRGVRKEYWLLV------DGLWDRRIQKMESQIasigRGKYANVESGGKAAASTFRVL---------GLDEERRVSWMSGLLKTGRTHQLRLHALKAGCPVVGDPLYGKSRDDGLFG---------LHARSLRMRHPASGEELSFEAEPPDEWRGLLERF--------------------------
>UniRef50_C0GQU7(87-269:318) Pseudouridine synthase n=1 Tax=Desulfonatronospira thiodismutans ASO3-1 RepID=C0GQU7_9DELT  E=4e-39 s/c=0.89 id=29% cov=70%
-LQIVFENPDFTVLDKPAGVPVHSGTSARRDNMVLrLRKHYAGADFSPALVHRLDKETSGLLLAAKNYAWLRRIQAMWNKNLVEKTYLAWVHGsWPSRWVNLEHRLIKTFEK-----MQPSPEGRPALSRVRSIAS-----------SRDKTLVQIRIITGRTHQIRTQLSLSGHPVIGDGKYGKDS---------GYAEMYLHAYMLA-----------------------------------------------------
>UniRef50_C0QC81(75-291:295) Pseudouridine synthase n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QC81_DESAH  E=8e-39 s/c=0.75 id=32% cov=70%
---------------KPSGMSVHNHPGSdllcvlerqIRADEDLMVALGAQEGFQIHPVHRLDQETSGLILVATDPDRLRYLSNLFQQGAVQKHYIALVHGNFDPPcdpfQVWDTPLSKQAGGRTDPRGKGKRV--RSETRYRIMDQ-----------SPHYTLLEIELVTGRKHQIRRHAKLAGHPVTGDTRYGSKRSVEFLRENHAYDRLGLHSFKIEFI---------------------------------------------------
>UniRef50_C3WCY4(90-292:292) Pseudouridine synthase n=1 Tax=Fusobacterium mortiferum ATCC 9817 RepID=C3WCY4_FUSMR  E=2e-38 s/c=0.79 id=24% cov=65%
---IVYEDDRVLILNKKANMVMHKGSGHEYGVSEILKEYLNNPNFNF--VNRIDKATSGLVVGAKSLVVTRELSEEIRERKVDKKYYILVEGKVKrREFQIKSYLKKLEDKVVE-LEQYEEGAKESLSFFKVVEY-----------GKNCTLLEGTLGSGRTHQLRVQLASMGNPIIGDSKYGKGKE--------------------------------------------------------------------------
>UniRef50_Q54UF9(240-441:578) Pseudouridine synthase family protein n=1 Tax=Dictyostelium discoideum RepID=Q54UF9_DICDI  E=3e-38 s/c=0.79 id=32% cov=65%
-IKIVSLDENVVVVDKPSSIPVHPCGRFRHNSLMYILASEHGINQ-LYGVHRLDRLTSGLLLLARTPDSANKKANQIQSGLVSKQYLAKVIGKFPgsdtinsssssfneqiklckhlEDGTfiIDQPIVIQSMRLGINHVGV--GGKPSITHIKLFSY---------DQSTNTSIVLCTPKTGRTHQIRVHLKWLGFPIANDPLY-------------------------------------------------------------------------------
>UniRef50_C8NY78(110-321:339) Pseudouridine synthase n=1 Tax=Corynebacterium genitalium ATCC 33030 RepID=C8NY78_9CORY  E=3e-38 s/c=0.75 id=28% cov=81%
---VVYEDDAIMVVNKPPFLATMPRASHITESATV-RLRRSTGNEELTPAHRLDRMTSGLLLFTKKASVRGAYQQLFASRAVAKLYEAVADDIgpsLPARPSANSPLVWEHHIVKREGELASSITVDAIPNSLTYVTDITPLQGG---AARYLL---QPVTGRTHQLRVQMHAAGAPIHGDPVYPEL---LPASAEDFTNPMLLTAVGLAFTDPLTGVKRTFSAP--------------------------------------
>UniRef50_P53294(119-304:404) Pseudouridylate synthase 6 n=8 Tax=Saccharomycetaceae RepID=PUS6_YEAST  E=3e-38 s/c=0.86 id=27% cov=65%
-FNIVFEDESILVIDKPSGIPVHPTGQFYQNTITELLKLH---GVDALPCYRLDKITSGLLILAKNSQSAGEIQKSIRSRDMIKIYLARVKGRFPHSELIldNENAAETTFEDTSKVTVEMtpiysidpkrqfpvglSTSKDAITKFYPIRYFSHADE---------TVVACKPITGRTHQIRIHLARLGHPIVNDSVY-------------------------------------------------------------------------------
>UniRef50_B4RU15(4-235:279) tRNA pseudouridine synthase A n=2 Tax=Alteromonas macleodii RepID=B4RU15_ALTMD  E=3e-38 s/c=0.69 id=29% cov=77%
-IPILFEDANLLVVNKPVGVAMHDAldskSGDPKDNALAIEHedtdknaaqkessackgedtlrtdgivtqLKKQLSlSELHLCHRLDTGTSGCLCLAKNAKTAAEIGELFSSRRIGKFYLALSEHKPKKKQG--AIIGDMKNRRGGQRILLKSQENPAITQF---------FSHAAKPGTRGFIV--KPHSGKTHQIRVALKSIGAPILGDSLYGGAPSD----------RLYLHAWHLRL--PLSAGELTITAPFD------------------------------------
>UniRef50_Q65TD3(4-200:217) Pseudouridine synthase n=7 Tax=Pasteurellaceae RepID=Q65TD3_MANSM   E=6e-38 s/c=0.81 id=28% cov=76%
-FKIIHKHRDFIIIDKPNGVSVHRDEAEIGLTGLLAKQLS---VAQVWLVHRLDKVTSGLLILALNERSAAEFSLLFARHEISKTYLALSKQKPKKKQGLIIGDMEKARRGAWKLCQTKQN--PAVTRFESVS-----------CEPNLRLFILKPQTGKTHQLRVAMKSLGSPILGDELYGGNSEKN--------DRTYLHAFRLEFT--YQGEPFRVQS-LPQ-----------------------------------
>UniRef50_A0LJK9(89-296:304) Pseudouridine synthase n=1 Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LJK9_SYNFM  E=6e-38 s/c=0.76 id=28% cov=78%
---ILYRDAHLLAYDKEAGVPSQQTPADAYNNLYAalirfLAGEARASAPYVALHHRLDRETSGVMVFALDRAVNRRLGESFQEKRVVKDYLAWVDGVPVLDRW--TAVEDICRKDGRYRTCPQGRGKAARTLLRVLLRA-----------GDRALIAARPVTGRTHQIRLHLAACGHPVIGDRLYGGTSGERLHLHALRLRL----------PHPKHDSELVLSAPVPEYWPE-------------------------------
>UniRef50_C1MIE2(196-542:547) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MIE2_9CHLO  E=7e-38 s/c=0.46 id=28% cov=88%
-LEVIHEDDAILVVNKPPGLrfhPVHRFEGNSLLSRCIGHIRRRRRRRRrasddggedggedadadgeekvdddedahaddmPHIVHRLDMDTSGVCVFVKDKSLVDGFARQFRGDDagVKKEYVALAVGTVPRGDvvafsseaeevrdddddaaaaaaaaavgrafVVDAHIGDHATMPEARAVHPPPlvasttratdpsadasAPKPATTACVVSSSAAAR------DGLVAALVRCAPRTGRTHQIRLHLALANLPILSDPLYGPHVRFGGAAMAENargkaggeeedgggggdrgyfaaelegywggdlwLGRQALHAASLTVRHPKTDVSMTFRAPLPEDMRRACVALG-------------------------
>UniRef50_A6DTB9(82-286:290) Pseudouridine synthase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DTB9_9BACT  E=7e-38 s/c=0.78 id=25% cov=78%
---ILYEDENLLLVDKPHFLPIHPAGPYVKETLV-YRLRESQNNPDISPLHRIDRLTAGLVFFSKKVSIRKDYQLLFENRLVEKTYHAISAGPAPDQGYW--HLKNRIEAGEPWFLSAIKEGKaNSESYINVIEAKDNLVKF-----------ELKPISGKKHQLRVHLASIGYPILHDPLYPSFVEKPP--DNYEKPMQLL-AQSIAFTDPFSKKRHSFQSQL-------------------------------------
>UniRef50_B7APK6(4-196:217) Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus ATCC 43243 RepID=B7APK6_9BACE  E=8e-38 s/c=0.82 id=29% cov=65%
--DIIYEDDGMIICRKPAGVLAQGSRSFDADMVSMLMTYRRKKGEdtYIGVINRLDRPVEGLMVFAKSSRDAARLNRLMQQDTFNKTYIAVVWGCIDAvEGTLTDYLVKDAGNNTSHVASEgEPGAKRAELNYRVIGSLD-----------GMSVVRIQLVTGRHHQIRVQFASRGHALVGDAKYG------------------------------------------------------------------------------
>UniRef50_Q54VB9(193-624:746) Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum RepID=Q54VB9_DICDI  E=1e-37 s/c=0.37 id=28% cov=87%
-LDIVYEDKDLAIINKPAGMLVHPTALtlgsnalvinkeDQTHTLVNALIHRYggvenlssvGGVERPGIVHRLDKDTAGMIIIARNNDVHQKLQTLFEKHtstmithttidqyedngsisnnqiermlqgkkiplTISKKYHCIVLGKPKEQhGFINKKISRHPAD-KNKMVIDQDNGKEALTEFKVLKVWENVNAkvldnqknkqtskqqtttnnnnnnntttnniinstlseydnamnqlhknkkkntkksnitsknvnsrmqflsvddddeeekedgdedekededeeenedeedeeeeddeeedeeeeeeddddedeeeeeddeeeedeeenydeiilrlqqkTKMITSNTFSLLEVTLHTGRSHQIRVHMASENIPIVGDPIY------SSKSKQFLVSYLLLASMNLKFVHPILNEIKEFSIQYPSHFKNFIS----------------------------
>UniRef50_D1SY25(116-317:328) Pseudouridine synthase n=1 Tax=Acidovorax avenae subsp. avenae ATCC 19860 RepID=D1SY25_9BURK  E=1e-37 s/c=0.79 id=28% cov=78%
---VLYQDEHLVVADKPHFLPVVPTGRYLQHTLLV-RLKRRLGLDGLSPVHRIDRDTAGLVLFSVQRATRGRYQALFRDRAVDKTYEA-VAPWRVDVAFPRERSSRIEESPQFFRMHEVPGEANSLTRMEVL---DVDGAWARY--------RLSPVTGRRHQLRVHMAALGLPLRGDAFY--PEVNDPPEGDFSRPLQLL-ARAIAFTDPVTGRERRFES---------------------------------------
>UniRef50_B7CDE9(49-252:253) Pseudouridine synthase n=1 Tax=Eubacterium biforme DSM 3989 RepID=B7CDE9_9FIRM  E=1e-37 s/c=0.78 id=26% cov=68%
-VDILYENTFLIVAFKPPFLLVHDDGNNQDTLqaRVNGYLQLNQNKYPAQAIHRIDYETSGLVLFCKHPFFQAYCDKNMEEHHIKKEYIALVQGHTNyKNKKIISNIARDRHNAKKMIIH--PNGKESVSIFNTLKNYK-----------DCSLIQVTILTGRKHQIRVQCASLNHPILNDSLYGGKKIDNTG----------------------------------------------------------------------
>UniRef50_A9UX27(112-295:401) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UX27_MONBE   E=2e-37 s/c=0.86 id=29% cov=64%
-LSIVGETPDLLAIDKPASIPVHPCGRYRHNTVqAILGHEHDRW--RVYPCHRLDRLTSGLLIFCKNPAMAKQFEQWITQHQVEKQYICRVQGRVEQSVLfCDAPLKICDQRLGLCCVHPE--GKASLTRFRVIRRDKDT-----------TVLHCFPKTGRMHQIRVHVQYLGHPIVNDPVY-------------------------------------------------------------------------------
>UniRef50_UPI00006CDA44(89-306:881) RNA pseudouridylate synthase family protein n=1 Tax=Tetrahymena thermophila RepID=UPI00006CDA44  E=3e-37 s/c=0.72 id=28% cov=78%
---IIYENKNIIILNKANGVSCQGGQDVSLNLVTMgQQYLINQTNQKYLVAHRLDKVTSGVLMVPKNQQIAKIYGNLFNDKSnINKYYIALVRNSPKNfKAMINAPIEYSQSKQRAIVSnIIDENSKSAHTHYQVLAQFKMEDKNLAAKIinsehdyikdwGDFSLLKIRIQEGRKHQIRVHLSEIsKTPIVGDARYFDKNHQESLFQYNKDQSIFLHCYQ-------------------------------------------------------
>UniRef50_A8NJ16(2-226:268) Predicted protein n=1 Tax=Coprinopsis cinerea okayama7#130 RepID=A8NJ16_COPC7  E=3e-37 s/c=0.70 id=30% cov=80%
--------------NKPAGLVSQLGRqlpemktRDTLDKVLKQIERRLELKEALRPLHRLDTATTGCLAFATTQTSARSLSKQFAQGQVEKSYLALVSGgketFPGTSGRIDTPIKYQDGYFDGL----GTGGKLSLTEWSLLAS---------SPVLPISLVRLNLLTGNKHQLRIHMAkKLGAPILGDDRYSSSKvASKLLSEGRIKPNLYLHASDIAFVRyrqrgPQKRFRLGITAPLPAHFVEACKAF--------------------------
>UniRef50_C1N0H2(130-362:497) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N0H2_9CHLO  E=4e-37 s/c=0.67 id=29% cov=73%
--------DDLVAIHKPATMPVHPTGQYRKNTVLGYLAAHRRDLGKLFPVHRLDKNVSGLLVMARTPTTANAMRTQVEGREVSKEYLALVtmkifnaggnaetvaaaaltafareEGTDVFAARCDAAVAYDERaRVASCDVSVADGAKDASTAFELVARGEWGVGGGDGGGDGGSacpfedvvvrgglprralLVRCRPTTGRTHQIRAHLSRLGWPIVNDVKYGGARAADLGGDALALD---------------------------------------------------------------
>UniRef50_C1EDH6(65-322:345) Predicted protein n=2 Tax=Micromonas RepID=C1EDH6_9CHLO   E=4e-37 s/c=0.61 id=23% cov=91%
---VIHEDDDVLVIDKPAGMSFHnddlvtnlPGVLSTVRALQAKGELRgSDYAGELHSVHRLDKITSGILLLAKNERVASWLARQFARRRVHKYYVALSARKPSKKmGTVRGDMAQARRGTYKLTRCSSNSTPAAVTKF-VSRGVRGASPGGDRPLR---VLLMRPLTGKTHQLRVCAKSLGAPVLGDAAYGGADTNKNANKNDGAggeDRGYLHAAALRVAMP-GGNVMEVVCKPTEgrewthasaGFHDAWTSFGFDELIGADE----------------
>UniRef50_Q6AJJ4(19-236:238) Related to ribosomal large subunit pseudouridine synthase D n=1 Tax=Desulfotalea psychrophila RepID=Q6AJJ4_DESPS  E=5e-37 s/c=0.72 id=30% cov=78%
-LPIVYEDNDIILVDKVAGLAT--TSRDKDNENTAYFRLTNYVKKgvakssnRVFLIHHVDKEASGLLIFAKTEKARRHLLDNWSDFNV--SYVAAVHGVPVQtEGVLRANLAENMIHKMYVTVAGEKT-RPAETEYSLLQH-----------SANYSLLSLRPKTEVKHQVRVQLADKGHSIIADKIYG--------VKSDEMKRLALHAAHLTITHPHTKKEMSFESRVPGHF---------------------------------
>UniRef50_Q9LU60(132-311:395) RNA pseudourine synthase 7 n=12 Tax=Embryophyta RepID=PUS7_ARATH   E=6e-37 s/c=0.87 id=32% cov=65%
MIDdvvILHQEPDVVTVCKPASVPVHPCGQYRKNTIVGILDAEHDLGT-LFPIHRLDRLVSGLLIIARTAAKADFFRQQIEGGMVKKRYIAKVIGVFPEdEMIVDANINYNGSEGRSTAEDANSSgddkkvkGKPACTKFTRIDT-----------NGTHSLVSCEPVTGRTHQIRVHLQYTGHPIANDPLY-------------------------------------------------------------------------------
>UniRef50_B2S1F9(100-286:320) Pseudouridine synthase n=2 Tax=Borrelia RepID=B2S1F9_BORHD   E=6e-37 s/c=0.83 id=27% cov=64%
---IVYEDEDLLVINKRRGALVHGDkySLGALINSYLLDENLESLSFKPSSVHRLDRNTSGLIIFAKNIDSARILSRAFSSGIVTKKYLALLDGEIKKPLTYRNFLYRD-RIARKTFVVNDEGRCNAITDVKPILVSKSS-----------TLAEVSIRTGFTHQIRAQCAFNKHALINDKKY-------------------------------------------------------------------------------
>UniRef50_B7RZ07(2-143:143) Putative uncharacterized protein n=1 Tax=marine gamma proteobacterium HTCC2148 RepID=B7RZ07_9GAMM  E=7e-37 s/c=1.10 id=46% cov=55%
---------------------------------------------------------------------------------------------------IDHALQDQPDKIADRNRTQARPTRDAVTRFERLDTVEIPYAVDRYPQSRYSLVALQPEQGRKHQLRRHMKHLGYPIIGDAKHGKGVHNRFFAEKYGCGRLLLACTGMDFSHPVNGDTVHIRAGLDAAFQRVLSAFGWKEPSP-------------------
>UniRef50_Q5XET6(181-467:478) RNA pseudourine synthase 3, mitochondrial n=10 Tax=Magnoliophyta RepID=PUS3_ARATH  E=8e-37 s/c=0.54 id=31% cov=65%
---VRFKDSAIIVLNKPPKLPVKGNvPIHNSMDALAAAALSFGNDEGPRLVHRLDRETSGLLVMGRTKESIDYLHSVFSDYKgrnssckawnkaceaMYQQYWALVIGSPKEkEGLISAPLSKvllddgKTDRVVLAQGSGFEASQDAITEYKVL----------GPKINGCSWVELRPITSRKHQLRVHCAeALGTPIVGDYKYG------------------------------------------------------------------------------
>UniRef50_B1ZYD0(18-255:255) Pseudouridine synthase n=1 Tax=Opitutus terrae PB90-1 RepID=B1ZYD0_OPITP  E=8e-37 s/c=0.66 id=33% cov=85%
-VEILERDPNgLLALSKPAGVLSHPNEG-KDQPRSLLTCHFDAVaecyvwtpegaatSQRWWLLNRLDSATSGVILLAANEELAREIRAQFKRKQVTKVYQALVFGKPP----------RPVELWRDVVAVTKQGGQIRTTagAGRVPAECRMSVVRSRGVGEGaLALLQLEPRTGRSHQLRVQCAKRHVPIVGDQTYGDFRHNREFAKRTGEKRLFLHSLATRFEYAWKGRTHVFaaQAPLPAEFGQVW-----------------------------
>UniRef50_Q9UJJ7(9-237:312) RNA pseudouridylate synthase domain-containing protein 1 n=23 Tax=Deuterostomia RepID=RUSD1_HUMAN  E=1e-36 s/c=0.68 id=29% cov=83%
-LSIVYRSRDFLVVNK--HWDVRIDSKAWRETLTLQKQLRYRFPELADPdtcygfrfCHQLDFSTSGALCVALNKAAAGSAYRCFKERRVTKAYLALLRGHIQESRvTISHAIGRNSTEGRAHTMCIEgsqgcENPKPSLTDLVVLEH-------GLYAGDPVSKVLLKPLTGRTHQLRVHCSALGHPVVGDLTYGEV----SGREDRPF-RMMLHAFYLRI--PTDTECVEVCT--PDPFLPSLDAC--------------------------
>UniRef50_B8HC32(88-317:326) Pseudouridine synthase n=1 Tax=Arthrobacter chlorophenolicus A6 RepID=B8HC32_ARTCA  E=1e-36 s/c=0.67 id=30% cov=84%
-LSILHQDEHLLVVDKPHFLPTTPGGTYIQESALV--RLRNQLDlPDLIPMHRLDRMTAGVLLFSTNPQTRGKYQVLFEKRQVQKEYECVSAADPaPGHPAVEFPVVVRNRMTKSRsylLAEVVEGEPNAETRIERLETFDGGASPDTNGStaavpgspTRLARYRLEPHTGKTHQLRVHMASLGLGIVNDAFYPDL---LDKAPDDYAKPLQLLARGIRLVDPISGSPVEYRSSL-------------------------------------
>UniRef50_C4Z1D5(1-212:225) Pseudouridine synthase n=1 Tax=Eubacterium eligens ATCC 27750 RepID=C4Z1D5_EUBE2  E=2e-36 s/c=0.73 id=26% cov=77%
MLNIIHETKDIIIVNKPAGQLSQGAKGFDLDLVSEVMTYNASQGKPAYaaIINRLDRPVSGLVLIAKNKSAAAKYSTLMQkEGGFNKQYEALICGKLSESkGTFVDYLKKDGRTNTSAIVPadaaaNDKEAKLSKLEYEVISYDEV---------KDITHVRIHLITGRHHQIRVQFASRRHPLVGDYKYATADcgmDNAVKAVAFKRNQIALCAVSLTI----------------------------------------------------
>UniRef50_D1VRZ3(85-279:316) Pseudouridine synthase n=1 Tax=Peptoniphilus lacrimalis 315-B RepID=D1VRZ3_9FIRM  E=3e-36 s/c=0.79 id=26% cov=71%
---ILYEDDNICLMKKPLNMLTHNDKNFYQDNMVDRfidylifkeeYSPREENTFRPSICNRLDRNTSGILLGAKNAETLREINKAIKERLVDKFYLTIVKGKVQKPFEINIKLEKTDKNI----MRKSSQGKDSLTKFFPLIS-----------NGEYSLLKVKLITGRTHQIRASLKEKGLYILGDRKYGTGKDK-------EFNSQALHNYLIKF----------------------------------------------------
>UniRef50_A4CVN5(20-213:215) Pseudouridine synthase n=1 Tax=Synechococcus sp. WH 7805 RepID=A4CVN5_SYNPV  E=3e-36 s/c=0.79 id=32% cov=74%
----------LMVVDKPAGLLCQPGLGSHQQDSLISRLQLACPA--LRLVHRLDRDTSGLVLLAKDPDMLRLLGMFFASRRVRKLYVADVQGQMKNvSGLIGLPLAR--LKRQPPTYGVHPGGKACVTLWRRLKLME--------SSTRLWLC---PRTGRSHQLRAHLAALHHPIIGDPIYNPG----------CAVGLRLRAMALRFPDPDdpSGQ-VRVRAPWPAWF---------------------------------
>UniRef50_B5Y592(1-175:175) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B5Y592_PHATR  E=4e-36 s/c=0.88 id=30% cov=65%
-LKIVHEDEHIIVVDKPSGVLTVPSDKN---VPSLAQAVFDHCQPtevtlDQMVVHRLGMDTSGLIVLAKTMDTVRQMNALFRTRKITRQYEALVVGHLPQHgGLISLPLMRDYEHPPY-MRKLLEMPKESLTKYEVVNREDM-------DGTPVSRVALTSISGRTHQLNVHLAAFGHPIVGDSVY-------------------------------------------------------------------------------
>UniRef50_C8PQZ0(8-266:276) Pseudouridine synthase n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PQZ0_9SPIO  E=6e-36 s/c=0.59 id=26% cov=92%
---IYFEDDYCAVVYKLNG-----------ENAQTFFTPLFPHKPFIAPINRLDTPVSGIILLAFSAQAQTLLSQAFKTGSVEKEYWAICE-RTAADTTEEEPGIHRLEHWLGFHTKTQKAFVGAapiditltnttaagITKPKKHKKPALKKAVLYWtlcgKGDRYDFIRISPETGRTHQIRVQMAAAGHPIKGDLKYGARRSETGGGIR-------LHSYKLSFSHPVTHQDITVQAPPiqPDTlWKACMAACTNSTTFSNKGEADAGADTTAPATLPT
>UniRef50_A8L7E9(13-238:285) Pseudouridine synthase n=1 Tax=Frankia sp. EAN1pec RepID=A8L7E9_FRASN  E=6e-36 s/c=0.68 id=35% cov=73%
----IFEDEAVLALDKPVGVSVMGERHDTD----LVSMARD-AGEELFPAHRIDKVTSGVVLFAKELRFHGDLTRQFNRRTVEKTYLALTRTRgLPALATIDLPLsvgRKNRVRIAANRADIVAWPGPAGTptpdgpagtpgsdgpagsgarspaSWTVPAARTFPNVRSYPSVTRiarvwegaeHTLVAAYPISGRRHQIRVHLAWVGHPIEGDPL----------FDRAPVTRTFLHSWRLSF----------------------------------------------------
>UniRef50_UPI0000384AA5(1-161:166) COG0564: Pseudouridylate synthases, 23S RNA-specific n=1 Tax=Magnetospirillum magnetotacticum MS-1 RepID=UPI0000384AA5  E=6e-36 s/c=0.95 id=26% cov=61%
------------------------------------------------------------MILGRHAKSIKRLGRMFEHHRVEKLYWSVCHGSPEgDSGTVDAPLLKVSGRGQGWRIKVDPAGQSSITDWSVLGR-----------GGGLSWIEWRPRTGRTHQIRIHAQHLGCPLLGDAYYGPDPET--------MTRLHLLAREVSFPaLSPSKDPVRVTAPPPGHMVEALRVCGWR-----------------------
>UniRef50_D2Q929(36-257:264) Ribosomal large subunit pseudouridine synthase D n=19 Tax=Bifidobacterium RepID=D2Q929_9BIFI  E=8e-36 s/c=0.68 id=28% cov=82%
--EVLYEDDGIIVIDKPHFLATTPRGMWYRETALI--RLRERYGEpDIVPAHRLDRLTAGVVVFVRKPELRGAYQMLFQEHRTVKTYECLaplapvVRPRYGTVTRIDrnqpFPLVRRSHIAKDRGRLQAYEIPAAVNAESLIERGDNPRIIDGNVVINYVL---HPKTGKTHQLRVHMNSLGLPILGDVFYPDVIQRPYDDFSRPLE---LVARRLEFDDPVTGESRAFVS---------------------------------------
>UniRef50_C7H3R7(122-322:365) Pseudouridine synthase, RluA family n=3 Tax=Ruminococcaceae RepID=C7H3R7_9FIRM  E=1e-35 s/c=0.76 id=26% cov=73%
---VIYEDENIAVLYKPTHLLCHSDRTGDANLVDAFTQYLAQKGEYdaggenrfkPGICNRLDRGTEGLVIAAKSYAALRDMNEIIRTDLLKKEYYTITVGIPQSGRFTAWweHDEKNNKVSIHAHQSQDERRKQIITDVDVLRTA-----------GPFALCKIGLVTGRTHQIRAHLAYLGKPVLGDIKYGNRKMN----ERTGTRTQALCAVRISF----------------------------------------------------
>UniRef50_Q317H5(103-308:332) Pseudouridine synthase n=2 Tax=Desulfovibrio RepID=Q317H5_DESDG   E=2e-35 s/c=0.73 id=32% cov=76%
--------DGLLVINKPAGLPVQPGTGHTDCVTARLAAHFAGADFMPAPAHRLDKNTSGLLLAGTTYTALRTLQDLFRNgHSLIKDYCAWVCGiWPEQEAltLTDVLVKEGTPGKEKIHALPAGSAQPHTAPPKGREALCQVVPLLRLDNA--TLLGIRLATGRTHQIRVQLASRNHPVIGDVKYGAPACRA---------GMLLHAFRLVLPAPFGRE---------------------------------------------
>UniRef50_A0JSJ6(88-307:314) Pseudouridine synthase n=2 Tax=Micrococcaceae RepID=A0JSJ6_ARTS2   E=3e-35 s/c=0.68 id=29% cov=83%
-LSILHQDDHILVVDKPHFLPTTPGGTYIQESALV--RLRNQLDlPDLIPMHRLDRMTAGILLLSTNPETRGKYQVLFEKRQVQKEYECVSAAEPAAGyPAVGFPVVVRNRMTKSRsylLAEVVDGEPNAETRIELTKTFD--AGTHASEPARRGLYRLEPHSGKTHQLRVHMASLGLGIVNDAFYPELLDKAPDDYTRPLQ---LLARGIRFIDPITGQPVEYRSRL-------------------------------------
>UniRef50_O16686(148-314:432) Uncharacterized protein K07E8.7 n=2 Tax=Chromadorea RepID=YK27_CAEEL  E=3e-35 s/c=0.90 id=29% cov=64%
-IRVISETDDLFVVEKPPSLPVH-TCGQYAIHTVLGQLRVNEGRTGLRVLHRLDRATSGVLLFAKNYETDLEFKTTLKQGEWSKEYICKVDGVFPdEEQVCEQPIGPLVISMGIQCVRPD--GKDAKSRFRKLWSDGTQ-----------SVVQVHIETGRTHQIRVHSQFLGHPIAGDQIY-------------------------------------------------------------------------------
>UniRef50_UPI0001BC98D7(113-324:324) RNA pseudouridine synthase family protein n=1 Tax=Pseudomonas syringae pv. tabaci ATCC 11528 RepID=UPI0001BC98D7  E=3e-35 s/c=0.71 id=28% cov=80%
VLEtILYADEHLVVADKPHFLPVTPA-GEYVEQTLLRRLIHRLGNPDLVPLHRIDRHTAGLVLFSANRQTRSAYQALFPTRQIDKFYEAIA----PALPGLEFPRLHESRLVEGEpffRMQEGAGASNTRTQIEVLERQDQLWRYGLY-----------PVTGKKHQLRVHMAALGAGICNDPFYPDVVKNPVDDYQNPLK---LLAKGLRFIDPLNGKQRQFESLLELDW---------------------------------
>UniRef50_B7CDE6(82-278:295) Pseudouridine synthase n=1 Tax=Eubacterium biforme DSM 3989 RepID=B7CDE6_9FIRM  E=3e-35 s/c=0.76 id=27% cov=72%
-LDVIYEDENILIVNKPYGLLSQSDQSQNQDCLVNrVQAYLMEKNEYdpnkehsfaPSICHRLDRNTTGLVIAAKNANALRKVNEAIANRTIQKMYRAHVVGTFEQKDFTMCYYIRKENTIAKVSDKKLEGYQKALMDVHV-----------ERDDGENSICTITLHTGRFHQIRALMGHIQHPLLGDVKYGYHGKKRPIE---------LMAYRLEF----------------------------------------------------
>UniRef50_Q2SKD2(13-189:231) Pseudouridylate synthases, 23S RNA-specific n=3 Tax=Proteobacteria RepID=Q2SKD2_HAHCH  E=3e-35 s/c=0.85 id=30% cov=68%
--------DDLLVVDKAPGISFH----DEEGQPGLCSCVADTLGIRVYPVHRLDKVTSGLLLLPKTPALARELTEQFSLRQVEKYYLALSAHKPqKKQGKI---IGDMEKARAGAWKLTAGRENPAVTQF---------FSHSLQPGVRAFMV--RPLTGKTHQIRVALKSVSAPIAGDSLYG-------GRANKEFDRTYLHAYGVRF----------------------------------------------------
>UniRef50_B6K9V8(1910-2166:2780) RNA pseudouridylate synthase domain-containing protein n=3 Tax=Toxoplasma gondii RepID=B6K9V8_TOXGO  E=4e-35 s/c=0.58 id=28% cov=87%
--DVLWEGDGLTVIDKPPGW--HCSDVRYDPQTESRQLCCIVSSSRPEPLglycslrfnyptgklkecnfglgHRLDVDTSGPIIIAQTLEAWQWIRDQMHKRNISKEYICLCHGTLAEGfHVIDSPIITSTDGRRLQSYIHHAG-QPSLTVVKPLAHLEHRELRYPGSTTplQFTLNWVKIHTGRTHQIRVHLQSLldsrGRPhcLVSDDKYGNGQQVEDFQ---WCRRLFLHQHRLSFRD-LNDTPQCFVSPLRADLLSALRHL--------------------------
>UniRef50_A1SV26(85-290:303) Pseudouridine synthase n=3 Tax=Gammaproteobacteria RepID=A1SV26_PSYIN  E=5e-35 s/c=0.73 id=27% cov=78%
---ILFQDEHILVAHKPHFLAV--TPGGKYVNECLQNRLRRSTGiEALQTLHRLDRVTAGLVMFSVNPDTRHRYHQLFKTRQIHKSYQAIAS-------ISDAeNLTGQEWEIKNRIVQGEPRFRMRVTEG---EANSHSVIRCLRQSAQTALFELTPVTGKTHQLRVHMQALGLPILNDKYYPQLEP--LSADNYAAPLQLL-AKELQFIDPVTEKPRCFRS---------------------------------------
>UniRef50_Q00YR3(57-251:300) Probable pseudouridine synthase (ISS) n=1 Tax=Ostreococcus tauri RepID=Q00YR3_OSTTA  E=7e-35 s/c=0.76 id=28% cov=74%
---VLHESEAVVIVNKPRGMSFH-----SEFAPGALARLRTQMGERtaVMSVHRLDKPTSGILVFAKNARARDALSKAFEEREIVKYYVGMSNRKPRKKmGTVR---GDMTRSRRKAWMLTSTTESPAETKFVSFGARGMGERALRMFVFR-------PMTGKTHQLRVAAKSLGSPLLGDDTYGGER---------DVDRTYLHACAIRIPKSVLGETIQI-----------------------------------------
>UniRef50_A4BGF0(95-297:309) Pseudouridine synthase n=1 Tax=Reinekea blandensis MED297 RepID=A4BGF0_9GAMM  E=7e-35 s/c=0.73 id=30% cov=77%
--DILYEDEQILVVDKPHFLST--TPVGQFMKHTVTTRLRNRTGNMAItPAHRLDRATAGVLLLTKQRAVREAYQSLFLRREVEKTYHALCHPNPelPEQFEINLHLKENTDN---MFVRVLDAPPNSHTSAKRLARHSTGD-----------LYELRPSSGRKHQLRCQMAHLGAGIVNDIWY--PVAQDPSPDDFSRPLQLL-AKKLAFIDPFSGQRREFVS---------------------------------------
>UniRef50_Q1MQF8(110-298:321) Pseudouridine synthase n=2 Tax=Bacteria RepID=Q1MQF8_LAWIP   E=8e-35 s/c=0.79 id=29% cov=68%
----------FIIFYKPAGLAVHGGTGQTDSLAHRLSQHYAHSTFMPTPVHRLDKDTSGLLLVAKTYNSLRYFSELFASHSTQltKEYLAWVVGICP----WTQPIC--LEDILTKKQKQD--------NYSRLNSYQNKLQQTSAQKASLtvrcikqykdkSLLLIKLHTGRTHQIRIQLSIHGFPIIGDKKYGNT---------IRSHNLKLHAFRLSFP---------------------------------------------------
>UniRef50_A1KNV2(85-285:305) Pseudouridine synthase n=13 Tax=Mycobacterium tuberculosis complex RepID=A1KNV2_MYCBP  E=9e-35 s/c=0.74 id=30% cov=76%
-VPVLHQDADIVVVDKPHFLATMPRGRHVAQTALV-RLRRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARapVAPGLALPRLVRSRIVKRRGHLQ---AVCEPGVPNAETLVERIARD--------------GLYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPNV---ISVAAHDFSTPLQLLAQRIEFDDPLTGSHREF-----------------------------------------
>UniRef50_C1A2U5(95-321:360) Pseudouridine synthase n=3 Tax=Actinomycetales RepID=C1A2U5_RHOE4   E=1e-34 s/c=0.66 id=31% cov=80%
--EILHLDDDLVVIDKPHFLPTTPSGRYLRESALVRLRVR-LDNPDLTPIHRLDRGTAGVVMFSARPATRGAYQSLFEKRQVTKVYEAVSarpSRWDQDAPALDVPLVYRnhieARRGELRVVVDDSREPNSETTIE--ARGTGVSASGRAVLHTV----LRPQSGRMHQLRVHLAALGAGILGDRRYPDLLPDAPDDHSLPLQ---LLARELEFTDPLSGRARRF-----------------------------------------
>UniRef50_Q4PCI6(57-240:1096) Putative uncharacterized protein n=1 Tax=Ustilago maydis RepID=Q4PCI6_USTMA  E=1e-34 s/c=0.81 id=27% cov=65%
-IKIIHRDDDegILVIVKPGSIPVHAAGRYLRHTLVGLLQSEHGVDM-VYTTNRLDRLTSGIMVCSTKKETASRLGAQFAAGQVNKAYVCRVRGKFPQgEVVCKQPILTIDRQSGVNIVHPK--GKHCETIFVRLSY---------DASDDSSVVFCRPITGRTHQIRVHVQYLGHPICNDPIYG------------------------------------------------------------------------------
>UniRef50_A4QI08(95-315:322) Pseudouridine synthase n=5 Tax=Corynebacterium RepID=A4QI08_CORGB   E=1e-34 s/c=0.67 id=27% cov=83%
-IHVIHEDDDILVIDKPPYLATMPRGRHITETALVKMRVLTGNND-LTPAHRLDRLTSGVLVMVKKPELRGAYQTLFARREASKTYEAIaefVPGLLDNGPAIWESRIEKERGIVQAFVVE--GPVNARTELVSVTPVDDAEqsilEEMHGPLPRQARYVLAPSTGKTHQLRIHMRDFAAPILGDPLYPVLH---AVDDEDYTTPMHLIARTLTFVDPQTNEERTFVS---------------------------------------
>UniRef50_B7P2L1(14-229:263) Ribosomal pseudouridine synthase, putative n=1 Tax=Ixodes scapularis RepID=B7P2L1_IXOSC  E=1e-34 s/c=0.69 id=32% cov=78%
---VLHLSPHFVVVDKPADVVIntqrpdeHPVTVETLLKRLHPELVDTGVHHSFRFCHRLDFSTSGVLCLALHKQSARSAQRAFHQRLAKKYYVAILEGHVRDDHVlVDSPIGEDkRPQHSHKMCTADKDycvsPRGAQTRLLVLWR-------GLLKGRPATKVLLRPVTGRRHQLRVHCASLGHTIVGDFTYGEDASSR---------RMFLHACRLVL--PTEVETLDVETPDP------------------------------------
>UniRef50_UPI000197A463(73-296:310) hypothetical protein HcinC1_08895 n=1 Tax=Helicobacter cinaedi CCUG 18818 RepID=UPI000197A463  E=2e-34 s/c=0.66 id=27% cov=75%
-IEPLFYNDDFAIYDKPHNLLTHP--KGRFFHYSLNDILKSRFGIQANALHRLDKQTGGLVLCSINPKSKKALESLMQSRSIAKSYCAIVEGRVKAEILINEPIMTQKHKGDLAIKSiVSEKGKESRTLIRPLAYYKDS-----------TLIHALALTGRTHQIRLHCSYIGHRILGDPLYGVSEdksrfyleaPNLSPKEHkalFDAPFLCLNAYALRF----------------------------------------------------
>UniRef50_B9W8E1(110-299:405) Hydrolase, putative (Drap deaminase, putative) n=5 Tax=Candida RepID=B9W8E1_CANDC  E=3e-34 s/c=0.77 id=24% cov=72%
----IYEDNEILVVDKPSGIPTHPT-GNYYHNSLSEIIKQQYNMDSIWTCHRLDKVTSGVLVLAKTKNGGVKFSKLMRDSKqhTKKTYLARVSGKFPEGiHQYRCPIFAVNMNGYLMSGNMEELPTDSTTVFEQIKY---------NACLDQSLIKCIPITGKFHQIRIHLRNLGFPIVNDSFYqPDKQKNQLTLQKCNIERQL------------------------------------------------------------
>UniRef50_Q7Z110(101-347:350) Chromosome undetermined scaffold_37, whole genome shotgun sequence n=1 Tax=Paramecium tetraurelia RepID=Q7Z110_PARTE  E=4e-34 s/c=0.60 id=26% cov=75%
---ILYENDQIIILNKKHGYASQGGANPNYNIPEILNLYFKNF----YIIHRLDQLTSGLLIIAKNKDIATEISTIIQEKAfITKKYIAVVQGQIKvQKGLIDRPLLFNTNNQKQTCYNEEQllEGKylPARTSYEVIEEYQ-------YQDEMYSILDLQIFEGRKHQIRAHLSQvLNTPILFDQKYGFQftKTNRDLQTSIfgEDQGIMLQAKRIVF----------------------------------------------------
>UniRef50_C0N835(63-274:279) RNA pseudouridine synthase family n=1 Tax=Methylophaga thiooxidans DMS010 RepID=C0N835_9GAMM  E=5e-34 s/c=0.69 id=32% cov=72%
-LDIgqtlhIYYDEHVLdcepaepeliadmgqysIWNKPYGMLSQGSKWGDHCTITRWAEQHLTPQRNAFVVHRLDRAANGLIIVAHEKKAAALLSGLFQSRQIEKRYQIWVEGEFSEQATVDNPVKVDL----------DLDGRHAVSFFTRLK---------FDASKQQSLLDVRIETGRKHQIRQHAASLGHPVVGDRLYGNILQQ---------ENLQLKAYFMAFRCPYTAEE--------------------------------------------
>UniRef50_B0E0Y2(98-279:478) Predicted protein n=2 Tax=Agaricales RepID=B0E0Y2_LACBS   E=5e-34 s/c=0.81 id=31% cov=67%
-VKVLYHDveREFLVVDKPGSIPVHASGRYYRNTLIEI-LVNDFGYKKCYPANRLDRLTSGLMIIPLSPDRARVLTDEFTTGTVRKEYVARVRGRFPAQEIVcEEPLLTVDRQMGLNIVHPEGKVlfihlQPAKTVFNLIRYDE---------NTNSSVVRCEPLTGRSHQLRVHLQYLGFPIANDPIYSESR---------------------------------------------------------------------------
>UniRef50_B8P9A9(86-260:448) Predicted protein (Fragment) n=3 Tax=Agaricomycotina RepID=B8P9A9_POSPM  E=6e-34 s/c=0.83 id=32% cov=65%
-VRIIHHDreREFIIIDKPGSIPVHASG--RFFRNSLVEILKNDFGfKKVYTINRLDRLTSGLMIIPLSSSMANTLTQEFAAGTIRKEYIARCRGQFPEEELaCEVPLLTIDRQMGLNVVHPE--GKPAKTIFKRM---------HYDANTDTSVVHCEPLTGRSHQIRVHLQYLGHPVANDPIY-------------------------------------------------------------------------------
>UniRef50_A0KLM3(1-201:219) Pseudouridine synthase n=2 Tax=Aeromonas RepID=A0KLM3_AERHH   E=6e-34 s/c=0.73 id=26% cov=77%
MYRILAQHKDFMVINKGPGLGMH-DETDEAGLLhpGLVSRVKADTGLLLYPVHRLDKMTSGLVLLARTTEANRALSMAFAAREVSKQYLALSDRKPKKKQGW-----------VKGDMQKGRGGSWMLT--RTLDNPAISWFDSVSVREGLRLYRIKPRTGKTHQIRVALKSVGAPILGDARYGGTAADRGY----------LHAWRLAFT--LAGEAFDFVCPPDE-----------------------------------
>UniRef50_UPI0001792C80(31-253:278) PREDICTED: similar to RNA pseudouridylate synthase domain containing 1 n=1 Tax=Acyrthosiphon pisum RepID=UPI0001792C80  E=9e-34 s/c=0.65 id=29% cov=75%
-VEIVYKSNDFIIVNKPEDVFTNNHNKARPSLDVLLrkkypHLVNSNLEHSFYFVHRLDFVTSGVLCIALNKRACAKASCAMQKRISRKYYIALVRGHVSQDHldlTDSIGYCAREAEGNRKMCTIDKvcctGPRDAHTRLVVLER-------GVFMSYPATKVLLQLITGRRHQIRVHCSTIGHTIVGDYTY-------SGRKDISPSRTFLHSYRLEL----------------------------------------------------
>UniRef50_C3PFH5(74-267:268) Pseudouridine synthase n=5 Tax=Corynebacterium RepID=C3PFH5_CORA7   E=1e-33 s/c=0.75 id=26% cov=75%
---VVFEDGDLIVADKPHFLPT--TSNGRIVRETLQTRLRvDLNEDSIVPLHRLDRLTSGLVLCSRNPRTRAAYQQLFQKRVVVKHYRAQVAAPFSFDGTVRLGMRR---VRGERQVRVDSTGTPTVTRVRASGTTA----------------DVWPLTGHTHQIRVVLNHLGHPIVGDDTY---PVDRGLDLYDFSTPLLLSHVALSFSDPVTGRKREFQ----------------------------------------
>UniRef50_C4GD18(5-307:312) Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles DSM 14600 RepID=C4GD18_9FIRM  E=2e-33 s/c=0.48 id=28% cov=81%
--EIIYEDADIFVCYKPAGFATQTASALQADLVSELKNYRKSRGEsdYIGLIGRLDQPVEGLMVIAKNPRAAGKLEAAQAKGRIDKYYLALTQGLPKgpdcgqeadslhrkgewiflendmlpasrgKNGRLLAPEDKgtknghqpapedKGTKNGHQPAVKDKGAKktrlpapgtgEAKTAcqlapgtgeakkacllapgIKGARKARLEYQILDHSKTKdgraLALLRVHLLTGRRHQIRLQLSGLGSPILGDARYG---------ADPNGQPLALCACQLSFPHPGTGERISYE----------------------------------------
>UniRef50_C5LRC8(202-400:439) Ribosomal pseudouridine synthase, putative n=2 Tax=Perkinsus marinus ATCC 50983 RepID=C5LRC8_9ALVE  E=2e-33 s/c=0.72 id=27% cov=70%
-----------------------------------------------GILHRLDVGTSGPLLLA-HSYKGFYMGRLvFCSHQIDKEYVALVKGHMGTVGkniVISDRIKIlkstlDNGQSYSTTCVVAPDGKPSLTEVVPVAHY------NDGSGEEYSLVLVKLHTGRTHQIRVHMAYIGHPLVCDPKYGNPTDPEAAKAVCAIDRLwcprtFLHSYRLCYNQPMDvvdekDATVDVYVPMPLDLRLALAKL--------------------------
>UniRef50_Q6NEJ6(129-344:349) Pseudouridine synthase n=6 Tax=Corynebacterium RepID=Q6NEJ6_CORDI   E=4e-33 s/c=0.67 id=22% cov=82%
---VVYEDDTLLVADKPPFLATMPRGKHITNSATV-QLRRSTGIDELSPAHRLDRLTSGLLLFTKRKRVRGAYQTLFSERNVRKTYVATAQynPSITPGTIWRSHMTKTAGEIQGHIIDAPPNAETLVSAIERIDAPTQQHLHALHGTDvDLAHYTLKPHTGKTHQLRLHMLAAGVPILGDTIYPTI--LAEDAEDYSRP-MHLTSTELEFIDPLTGRPRLFT----------------------------------------
>UniRef50_A4E6R1(2-136:154) Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens ATCC 25986 RepID=A4E6R1_9ACTN  E=4e-33 s/c=1.07 id=26% cov=52%
-----------------------------------------------------------------------------------------------DEGTINTGIARSTRDRVKMAVSDDPFARQAITTFKVLERFDSTRFDD-----GYTLVECHLFTGRTHQIRVHMRHINHACVGDPLYGKC----DARADQGLTRQFLHSWRVAFEHPVTGERIECRDELPWDLAAVLDDLAPRSL---------------------
>UniRef50_C3WHA9(90-256:295) Pseudouridine synthase n=4 Tax=Fusobacterium RepID=C3WHA9_9FUSO   E=4e-33 s/c=0.86 id=27% cov=65%
---IAYENENLFIINKNLGDVIHKGSGHDISLLEEFRSYYSNNKINF--VNRIDKLTSGLVIGAKNIKTAREIAKEIQLGNILKKYYILVYGKIEKEEFILENYLKKDEEKVIVSDVEKEDYKKSITHYKRI-----------NGDNDYTLLEAELKTGRTHQLRAQLNHLGHTIVGDTKYGK-----------------------------------------------------------------------------
>UniRef50_C1FHP0(253-672:730) rRNA/tRNA pseudouridine synthase n=1 Tax=Micromonas sp. RCC299 RepID=C1FHP0_9CHLO  E=5e-33 s/c=0.34 id=33% cov=90%
-LHVVYEDEWLMAVSKPAGVMTYPAHRLRGESVVsrAVHHLSVSAARRrgrlpyssedlpeesgvgtpvgtpggsfagawtssqvePIAVHRLDLETSGVLLLAKDKRVASELQAKFEARGVRKTYLAVCAvledaeahkatatrrvdfeadvdtdvdsdadmdadvyadtdgdelGVFDESdldddddddayedpddeldeldepgvvRVVNAAIGDPEPGTRRSAAADDGGrcvravtpdGKPARTEYQCLSSrlgvptqVTMPDGVTRRTVVGTALVLARPLTGRTHQVRLHLAHAGFPIVGDGLYGvdyasvaasigafrlsgggitreereaaarrrllfassspssssavsPRDDASAGGESPGsespddvpspCARLALHAWNVDVLHPRALVPLRLCVDMPRDMTDLARALG-------------------------
>UniRef50_B0E5G5(146-314:402) Ribosomal pseudouridine synthase, putative n=2 Tax=Entamoeba RepID=B0E5G5_ENTDI  E=6e-33 s/c=0.85 id=30% cov=63%
-LTIVKETNDFIAIDKPSSVPVHPCGRYRHNTVIFI--LSHEGYPNLRPVHRLDRMTSGILLLAKTIQAARE----FQNHMVikKKEYICRVRGKL-EKTVVTSKIGRKRIDDKKIHVSVNKieeDGKECCSEFNPLFYDEKTNTT----------VAVALLgSGRTHQLRVHLQSIHHPIVNDPIY-------------------------------------------------------------------------------
>UniRef50_Q0F2T6(95-290:291) Pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F2T6_9PROT  E=6e-33 s/c=0.73 id=29% cov=74%
-------------IHKKSGQyaqeALHRSRGTLPDELARHLELTPAQASELRPVHRLDRDTSGLMLFSASAAMLQHLQAHWHD-AVEKRYLAVVSPAPDwDDQRIRLAIDRNRDAHGRYHLSPDGRACDSEAH--VVERRDNR-----------ALVELVPHTGRSHQLRVHLSALGCPILGDSRYGGKPH----------PRLMLHAVSLCIRPPALPETKQWNQPPEENWQ--------------------------------
>UniRef50_C7RAZ2(89-301:305) Pseudouridine synthase n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7RAZ2_KANKD  E=1e-32 s/c=0.67 id=28% cov=77%
--------EHFLIAYKPHFLPVMPGGV--FVNECLQQRLIDKTGnPNLQAVHRLDRDTAGLVMFSTNPHTRSDYHQLFAQQNIKKHYQAIAKTQAGESlsgkswhiknylaRSEPQFIFQNLDTSPDDTSPHDKDAQYAES-----------LIHCEDDNLQLGLFTLSPITGRTHQLRLHMMSLGFPILNDRFYPSLQPKQ--ADNFSQPLQLL-AHKLSFIDPVSKEPRAFTSPV-------------------------------------
>UniRef50_UPI0001BCD7D0(60-264:283) hypothetical protein AmarD1_17996 n=1 Tax=Aeromicrobium marinum DSM 15272 RepID=UPI0001BCD7D0  E=2e-32 s/c=0.69 id=30% cov=79%
-LTVLHRDERLVVVDKPAFLSTIPRGRHVAQSVVV--RLRDELGlPELSPVHRLDRVTSGVLVLTTERRWRGAYQGMFQHRRVHKAYRALA----PLRPDLELPLTVRNHLRKDRGAWQVTVDPDAQPNAETLVELDAVV-------GGLGVYRLTPRTGRTHQLRAHLCGLGIPIVGDPLYPAVLE--VDVDDFSTPLQLL-AHEVSFTDPVDGGERRFTS---------------------------------------
>UniRef50_A0YDZ6(92-260:280) Pseudouridine synthase n=1 Tax=marine gamma proteobacterium HTCC2143 RepID=A0YDZ6_9GAMM  E=2e-32 s/c=0.83 id=29% cov=65%
---------------KPYGVLCQGS--KWGDHCTIDRMIEIYTQKRSYLVHRLDRATTGLMIIAHSKDMAAKLSKLFRDRAIDKRYLAIVDG--------DFPYCEKKQTITSTL-----DGKKAISHMRRLRYSQRHHQ---------SLIDVNIETGRKHQIRRQLSDQGYPIVGDRLYNPAGDDKQHTADLK-----LCCYSLGFKCPIT-----------------------------------------------
>UniRef50_Q0S710(127-330:338) Pseudouridine synthase n=31 Tax=Bacteria RepID=Q0S710_RHOSR   E=2e-32 s/c=0.69 id=29% cov=75%
-IEILHRDEDLLVVDKPHFLASTP-RGAYVAESALVRLRRDFDLPELTPAHRLDRLTAGVLIFTVRREVRRDYQSLFDQRRVVKEYEAVAR---------YDPDLRLPATVRSRIVKERGvlkayemdGPANSESRIELLE--------IHGDAARYRLL---PHTGKTHQLRLHMSSLGIPIHGDNFYPDFYDVAADDYSTPLR---LLARSVEFVDPYSGVTRRF-----------------------------------------
>UniRef50_Q6MN39(1-205:225) Putative pseudouridine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MN39_BDEBA  E=3e-32 s/c=0.69 id=27% cov=77%
MIQIVFENTHFIICDKPAGVLSTPSRFEEDDARLCLGtALQKEKGFQIFPVNRLDFEVSGLVVYAKTAEAHRKANAWFEHKTVKKTYRALTTGQSYAHIPANVPneklkLTPEVGNTFEWRCRLLRGKRRA---YESPQGKEcLTVAVFRGMQGDYQVWDLNPVTGRSHQLRFDLSRHGFPIVGDKLYGS-------TVELADNRIALRSYRIDF----------------------------------------------------
>UniRef50_C4LE96(109-310:316) Pseudouridine synthase n=23 Tax=Gammaproteobacteria RepID=C4LE96_TOLAT  E=3e-32 s/c=0.69 id=26% cov=77%
---ILYMDEHLLIADKPHFLPVTPA-GDYVSQTLLARLVARLNNFELQPLHRIDRHTAGLVMFSVQKKSRAAYQALFRDRKIEKRYEAIA----PALPQIAFPHIRATRIERGEpffLSQETAGTANSQTIIDVIER--------RADLWKYAL---NPVTGKKHQLRLHMSALGAPIYNDAFYPSV--NDDVADDYQKPLQLL-ASELTFVDPVSGVKRHFKS---------------------------------------
>UniRef50_B5YM19(57-321:344) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B5YM19_THAPS  E=4e-32 s/c=0.53 id=28% cov=85%
-IPIIYENDQLLAVCKPPHISHHDDPaSNQLGLLSLIRLQqqqqqqqdesSFPYPHRLHGVHRLDRVTSGVLLLAKDSSVANELITKFRQGEVSKYYMAIsgkkpkkkkqgwVKGQMvmgrrgsyklvnENRDVLDEGDGDDEVEDGGEVSQVKKKGGYAVTRFYTaglgdLQLAPLPKCDGDESNDDELLipktaILFQPHTGKTHQLRVAAKSAGIPILGDVRYGGGTVTQR-EENANFDRTYLHASAIHFQ--LNDEDVTIWSPPP------------------------------------
>UniRef50_C5BI24(12-231:231) Pseudouridine synthase n=1 Tax=Teredinibacter turnerae T7901 RepID=C5BI24_TERTT  E=4e-32 s/c=0.64 id=26% cov=84%
----------FLLIHKYPGAVVHGTA--DSGEITLTQSLRHDFScKSLFPCHRLDRTTSGLLVVAKGEAANKYFSTLFEKRAIDKCYLALSAKKPaKKQGAVRGDMVK--ARNGSWMLTRSLNA-PAHTQF---------FSKGGVEGKR--LFVLRPITGKTHQLRVAMKSLGAPILGDERYGGG----------DADRCYLHAFALQFS--VDGNEYSYVCP-PEHGDLFCSQ-NFKSALDDLQSPfELPWPAAKNGQ---
>UniRef50_C8PQG0(2-214:231) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PQG0_9SPIO  E=5e-32 s/c=0.66 id=27% cov=73%
--------------NKPAGIPVHGSSSI--DTLLSAASVLTPSAEppaavpdtdgrvhlhslsfKPGPLHRLDKDTTGVLCFSRTLAGAQWFSQCLREKTVGKYYLGVVRGAMPAQPI----------------TAQDENG----------ATMTQCYSVEYCKDIDASLMLFRLITGKKHQIRKHTESVGHPLAGDRKY------HGGNPLPGCKHYLLHAWRLYFPalRPAD-IPASIEAPLFPEMETFLNRYfpNWRNA---------------------
>UniRef50_A7AQ79(154-365:465) RNA pseudouridylate synthase family protein n=1 Tax=Babesia bovis RepID=A7AQ79_BABBO  E=6e-32 s/c=0.66 id=27% cov=68%
-VRILHEDDDYIAVSKPSSLPLYHTGTYYYNTLveVLKNEVFKDSARTLYPVHRLDKLTSGVIILAKSSKAASEFCEGIRNSRFRKVYIARVKGDFtnvfgdHECISINDGIGvgngsvacchgfmrcvsHKLSMHEFTLDDTKKDVKVAETRFRMLSYNSSLDE---------SLLLCYPVTGRTHQIRAHLKYLGYPISNDKCYNDGE---------------------------------------------------------------------------
>UniRef50_C0QI10(85-289:298) Pseudouridine synthase n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QI10_DESAH  E=8e-32 s/c=0.68 id=28% cov=78%
--EILFHNDHLIAACKPHFLPVVPSGPHVNETLLNRLKIRF-SNPDIVPIHRLDRETAGVVLFSVEPETRGAFQHLFMEKKVKKTYEAVTRrpGTLPHLPSV---IVNRIERGEPWFRNTIVPGRPnAETRLELVG-----------ADRDRAFFRLYPQTGKKHQLRLHLASLGFPIENDRCYPDLLPKQG---DDWEHPLMLLSREVRFMDPIAGRERVFTSP--------------------------------------
>UniRef50_B9Z169(1-216:229) Pseudouridine synthase n=1 Tax=Lutiella nitroferrum 2002 RepID=B9Z169_9NEIS  E=9e-32 s/c=0.64 id=28% cov=79%
MFDLIATDPRFYVIAKHPGVSFHR----QGDEAGLMEALRAQLADDaLWPVHRLDRLTSGLLLVARSAEVASRLAEAFAAREIEKYYLAL----------SDRKPQKKQGLVRGDMVKGRGGA------WRLLPSSANPAITQFFSFSLAPGLRlfiLRPHSGKTHQLRVALKSLSAPILGDELYGGTPSDRGY----------LHAYSLAFH--LDGERFHFICPPrhgahfnAEALQAALQKPEWQ-----------------------
>UniRef50_B5EI85(84-287:293) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=B5EI85_GEOBB   E=1e-31 s/c=0.68 id=26% cov=78%
--EILFQNDELLVACKPHFLPV--TPGGEYLSQSLLHRLRESTGIHdLVPLHRIDRETAGIVLFSANPKTRGRYGELFREGSIEKSYEAI-SAAPVEPGQAEWLVENRLVHGEPWFtMRTEQGPPNARSLIRLVEQ--------RDGAARF---QLTPVTGKTHQLRVHMSGLGLQILHDRLYPQLQPQQP--DDFDRPLQLL-ARRVRFRDPLSGRLLEFES---------------------------------------
>UniRef50_Q69K07(177-345:448) RNA pseudourine synthase 4, mitochondrial n=5 Tax=Poaceae RepID=PUS4_ORYSJ  E=1e-31 s/c=0.82 id=31% cov=58%
-LEI-YKDEAIIVVNKPPGMPVQGGVGIKNSIDVLASMFEENSSEAPRLVHRLDRDCSGILVLGRNQLSTSMLHAIFREKTAdaladgtqhvlQRKYVALVIGTPRhPKGLLSAPLAKillqdgKSERLTIRASSNAASVQDALTEYRVIESC----------PQGYTWLELFPRTGRKHQ-------------------------------------------------------------------------------------------------
>UniRef50_B6WPU4(110-312:335) Pseudouridine synthase n=1 Tax=Desulfovibrio piger ATCC 29098 RepID=B6WPU4_9DELT  E=1e-31 s/c=0.68 id=28% cov=63%
-------DGDLWVFCKPAGLPTHPGTGHEDSLSSRLAAGAGDAPFKPTPVHRLDKDTSGILLVAASFAVLREMTTALRERRMKKEYLAWVEGLWPHSGVRlfRHWLRKEAGTgngreqmHVRQTGAPDKGETEALLLVRPVRVEDRRSLLLVRLL-----------TGRTHQIRAQLSSLGHPIEGDVKYG------------------------------------------------------------------------------
>UniRef50_A3QIB6(96-310:313) Pseudouridine synthase n=4 Tax=Shewanella RepID=A3QIB6_SHELP   E=2e-31 s/c=0.64 id=29% cov=80%
---ILYLDEQIVLANKPHFMALHP--GGEVINQCLINRLRERTGcETLIAAHRLDRATAGIVLLVKQSDSRDAYHGLFRHGQITKEYQALAR--LTPELLAEYHAGKLSLPRRWTVKNRIDKGTPSFTmrivDGEANSHSEIALVSVEGEIGRF---ELMPITGKTHQLRLHMNSLGMPILNDNFYPTLLPR---SAEDVAQPMKLLARRLAFTDPVTGRKLDI-----------------------------------------
>UniRef50_C5L5W9(272-515:604) Ribosomal large subunit pseudouridine synthase D, putative n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5L5W9_9ALVE  E=2e-31 s/c=0.57 id=29% cov=86%
---VLHRDADFIAINKPWGLSVTDGPKVKYSLQRHLRAFTSPSSSEVPIlIHRLDTATAGVQLLARHKSAATMARDRIGARSFwNRIYWVLVWGRVqlgprQFSGTINIPLIHRGHHV--KPASFHTAELSAITRWEILK--FSPFAGG------ITLLKLEPYTGRRDQLQAHCAFgLRTPIVGDDVYSKeaIRWNDAYPEKHMLQRKemfgeelickrMVCSRQIS-MHSFGGDQIDIIAPVPPHMQQMFDKLGW------------------------
>UniRef50_Q1JXL0(84-287:294) Pseudouridine synthase n=1 Tax=Desulfuromonas acetoxidans DSM 684 RepID=Q1JXL0_DESAC  E=3e-31 s/c=0.67 id=27% cov=78%
---ILYQDDALLVACKPHFLPVHPGGRYVTENLVYRLRLATGNDQ-LAPVHRIDRFTAGLVLFAQRSEDRARYNALFSQGNIKKRYDAVAH-CPEEPQQRHWQVANRIEQGDPWFRwQVVAGDVNARSSIELLD-----------LRQGYGLFSLQPITGKTHQLRLHMSGLGFGLVNDRYYPNLLPEQP--DDFSTPLQLL-AKEVIFTDPVTGKHHHFESP--------------------------------------
>UniRef50_B0SSX5(17-217:231) Pseudouridine synthase n=2 Tax=Leptospira biflexa serovar Patoc RepID=B0SSX5_LEPBP  E=3e-31 s/c=0.68 id=23% cov=76%
---IFYECDDFLLAEKPEGIPVHETkdPSRMDFTRLLSNHLQ---IPELRTVNRLDLGTSGIVLLGKNKNKNVELDLLLKE--AEKTYIFLCDGIPSwREHRMECFLKE----GNKQVNLVRSGGKKAITEFSILHSDPNESISFGF---------AKILTGRRHQIRVMLSSLGFPILGDTVYGKKEKTET--------RMYLHSFRFYFTDFLGQKQM-VQTDVPRDW---------------------------------
>UniRef50_UPI00005230E6(163-430:494) PREDICTED: similar to RNA pseudouridylate synthase domain containing 4 n=1 Tax=Ciona intestinalis RepID=UPI00005230E6  E=4e-31 s/c=0.51 id=33% cov=65%
--NVIYADNKLVIFNKPYGLPMHDGDGTKQTVKNVLPFLSKmvygiNTDIPLHLCHRLDKNTTGITICSTDAEMADYVMGLFRQRRVLRKYLAVVVGEPEPmKGVVDMPMSESIVSATKSTKRHSRmiikpdvryddatgkeyplrnaGGHTAITHYRTIDT-----------TGDLSLVELQPQTTVKHQLRVHMADgLSCPILGDHKY-------------------------------------------------------------------------------
>UniRef50_D0WNY8(101-298:306) RNA pseudouridylate synthase family protein n=1 Tax=Actinomyces sp. oral taxon 848 str. F0332 RepID=D0WNY8_9ACTO  E=4e-31 s/c=0.69 id=30% cov=72%
-LDVV--DgtDRWIAVDKPAGMATMPRGKHVAQTVTIAAR-RHFSNPEIVAAHRLDAATRGVLLLTLAKRWRAPYQMLFERREVRKAYLAVapADDRFVEAQTVALALAKPRGSLKALVVDGQPN---AVTTVRLADERR-----------GLGLYEIEPKTGRTHQIRVTMSHLGIPIVGDWLYPEVRDGGD---------LQLLAARLEFVDPANG----------------------------------------------
>UniRef50_B7G895(96-326:383) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G895_PHATR  E=5e-31 s/c=0.59 id=25% cov=78%
-VPVLFQDDQILVVHKPSGVAHHNDAdTGRLGILNLIRHqqttGRFAYPHRLYGVHRLDRVTSGILVLAKTPGAAQILTQAWREDRVTKYYVGLSGNKATTSKQGHVRGRMIRGRRRSWlLTRETHGSNVAHTRFFTAGLGHLaPPSSTLTNVSPKTLLLFRPTTGRTHQLRVAAKSVGLPLWGDPVYRDGRHRTENASTP--SRTLLHAA--------------------------------------------------------
>UniRef50_A4S4W6(2-178:178) Predicted protein (Fragment) n=1 Tax=Ostreococcus lucimarinus CCE9901 RepID=A4S4W6_OSTLU  E=6e-31 s/c=0.77 id=28% cov=62%
---VLYENDAVVIVNKPPGVSFH--SEFEPGALARLRASRDAREERLRAVHRLDKGTSGTLVFAKTADAAKKLSDGFATRAIVKYYVGI-SGKKPKKkmGTVTGDMARARRKAYKLTNTKDN---PAVTKFVSFGAKGRRMFIFR------------PLTGKTHQLRVCAKSLGAPLLGDDVY-------------------------------------------------------------------------------
>UniRef50_B3PEA2(114-290:291) Putative pseudouridylate synthase n=1 Tax=Cellvibrio japonicus Ueda107 RepID=B3PEA2_CELJU  E=7e-31 s/c=0.77 id=34% cov=68%
---------------KPHGLLAQGSQ--WGDHCSLLRWVEVVRQRECFLVHRLDADAAGLILIAHDAQAAAALSQLFQGRSLRKHYQAWVSGELQATGlRLEQPL----------------DGKDALT--------WVNTAVIDQPNNR-SLVDVRIETGRKHQIRRHLAAIGHPIMGDKLYGQANQ----------QPLQLLAWQLGFECPLLKRPITISLPEPLKFR--------------------------------
>UniRef50_Q21JF5(2-189:209) Pseudouridine synthase n=1 Tax=Saccharophagus degradans 2-40 RepID=Q21JF5_SACD2  E=7e-31 s/c=0.72 id=36% cov=53%
------------------------------------------------PAHRLDKPTSGLCIFAKSSGAAAQFGQLFERKLVTKYYLAITSKKPaKKQGAIIGDMVKTRNGSWKLTAAKTN---PAITHF-----FSFALASGMR------LILLKPSTGKTHQLRVALKALGAAIIGDERYGGEPSD----------RLYLHAYQLEF----------------------------------------------------
>UniRef50_C3XCW5(97-305:319) Pseudouridine synthase n=2 Tax=Oxalobacter formigenes RepID=C3XCW5_OXAFO  E=1e-30 s/c=0.65 id=29% cov=77%
---VLYQDDWLVVADKPHFLPVTPSGKYVSETLLV--RLRKKLGIDtLTPIHRIDRETAGLVLFSVKPEGRNLYQRLFRENFVSKHYEAIA----PYRDDIAFPMRyrsriEEGDSFMRMRVIPDGTP-NAETEISI-----------QQKSNAFAHYHLKPVTGRKHQLRIQMCSLGIPLLNDRIYpvhlPEAVTDEMQAEEFRYP-LQLVAKSVSFKDPVSEKIHHFES---------------------------------------
>UniRef50_Q04RC2(8-258:277) Pseudouridine synthase n=4 Tax=Leptospira RepID=Q04RC2_LEPBJ   E=1e-30 s/c=0.54 id=24% cov=83%
-IRIFYETESFLFAEKPPGIPVHATKDSKREN-FADRLQEQLSLEYLRTVNRLDLDTSGLVFLCKNPDKNKEADRILKSSS--KIYLCVADGIVEEEHFTETCYIKDGNKKVRKVF---SGGDKAVTEFLTLK---------RNLKDHYSVLLAKLHTGRRHQIRLHLSEKGHSIVGDYVYGKSldlnsttkrkpmetspsdnrisniqkrnflnketitAPIRAKRRVSFAQRSLLHAIGVSFRNEGGYEERIF-CPPPIDFQKFLE----------------------------
>UniRef50_C7NC29(99-301:314) Pseudouridine synthase n=2 Tax=Leptotrichia RepID=C7NC29_LEPBD   E=3e-30 s/c=0.66 id=26% cov=68%
---IIFENEDFFIVNKSEKIPMHKGTGHKYGLAEVFKEIFKNENINF--ANRLDFETSGLVIGCKNLKFLRYISQKIRDNEIQKKYFAIVHNIKNniESKIfkIENYLTTTENKVIVSENPISKDSKKSITNFKKILISELKNTKKILDlleknNKNVFLLDVDLVTGRKHQIRAQLAHQKIPIVGDKKYG------------------------------------------------------------------------------
>UniRef50_D2VYL5(155-352:464) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VYL5_NAEGR   E=3e-30 s/c=0.68 id=28% cov=65%
-IRVLYHDDEFLVIDKPSSIPVHPAG--RFVKNSLHYLLESALGRKLFLIHRLDKVTSGVLIHTWNAALAKSYQDTMKEGNVRKCYLAQVYGEFPEtenmsgehvllNGQSFHKDKEGFIHVKNKMVykqndwtfiwradssengSDSTDPKNTDTAYTLVKRIYYDPASSR------SIVIAIPITGRTHQIREHLRVMGYPIIND----------------------------------------------------------------------------------
>UniRef50_D0N321(279-461:556) RNA pseudouridylate synthase, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0N321_PHYIN  E=3e-30 s/c=0.73 id=33% cov=58%
-VRVVYEDDDLIVVSKPPSMPTHPCGAYRHNSLhTILQATRPDLPQ-LNIVHRLDRLTS-------------------ADRQASKTYLARVRGRfpdvlssevqdklvtqakeicpasiitFPEEGavLISCPLRCLSARDGVWECHEE--GKPSETLVRLVRTDKCT-----------SLVKCKPVTGRTHQIRLHLQLIGFPIANDPCYGG-----------------------------------------------------------------------------
>UniRef50_B8LCC0(33-308:332) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LCC0_THAPS  E=3e-30 s/c=0.49 id=31% cov=80%
---------------------------------------RRQLSRKPYLVHRLDHRTSGAVIVGFDSKSAGVLHGRLRGGEARKLYVALVRGDLRErfrqaaaDGCCDGGLSailpeRNDVEEASKMKNVEKAqtyvaseyttkitvdlpinvkvdgvdvEKDATTDFYFIAsmcldeddsgRANDDTAKVPFTNKAVSLILCHPITGRTHQIRRHArKAFSSPVVGDREHGDSRVNRFWREKVGLDRLTLHCWYLDLPQaeedcvedrrgvdavmeEVSKTRIQCMAPLPPDFATALKHEKLKPLWEEVLRME-------------
>UniRef50_B5JF54(26-238:244) Pseudouridine synthase n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JF54_9BACT  E=3e-30 s/c=0.63 id=29% cov=77%
----------LLAIEKPAGVLSHPNKKGEKAKALLDAGYDEKRQAYsvldtesgetrlVYLLNRLDSATSGIVLLALEEGTAKAALKAFETKNVRKTYQALVFGAPRGGP----PLWRDRLSVKHAEGGVRasaGGGLSAET-----KLVKVELLPGVPLVSRLTLM---PITGRTHQLRIQTSKRRIPIVGDRTYGDFQKNKMAAKK-GMKRLCLHCVGTELQYQLSGRSFRFKA---------------------------------------
>UniRef50_A9GNR7(140-364:368) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GNR7_SORC5  E=6e-30 s/c=0.59 id=27% cov=73%
-LDVVLERDDLVVVNKPAGVPTaplHPGERGTVANALVARYPEmagiGFSPREPGLCHRLDTDTSGLVLAARTAAAFAALGAGLKEGRLDKRYLLICQiGDLPEMGSIEVPLAPHPKDKKRvypcihPRDVARYAPRPAATMYKRVRQVGLWELVEARAPRAL-----------RHQIRAHFASVGHPLAGDVLYGGPAVE-------GLSRHALHAHYIG-----------------------------------------------------
>UniRef50_A5IZG0(83-264:284) Ribosomal large subunit pseudouridine synthaseC n=1 Tax=Mycoplasma agalactiae PG2 RepID=A5IZG0_MYCAP  E=7e-30 s/c=0.73 id=27% cov=67%
--EIVYEDDNILLINKKAGTIVHGDSNCLDNQVFSYFKFRQNSAFRPSHVGRLDKWTSGLIMYAKNYQTLTEL-----NHKTEfldKIYV-LKSDYNPHDEIVSVYI--HHDELQQKMVATknmqHPNDKIAKTRF------------FKKDNKLYA----QLFTGRKHQIRATLEYLGYPIYGDSKYGSKTK--------GTKRVYLHCYKLKF----------------------------------------------------
>UniRef50_B5IKI7(87-326:350) Pseudouridine synthase n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5IKI7_9CHRO  E=1e-29 s/c=0.55 id=28% cov=75%
----LFDDGDLLVLAKPAGLPVLPAGGYLEHTVLRLLERQVRAGRldgrfgLPRPVHRLGRFTSGLLVCARRRASRAWLSALLRDGTAeasravplelqemvgeapaacRKLYRALagplpVSGPgaleLGETLRITTPIGRRPHqRLGEVWSAGGRNALPALTTITLLER-----------RGHGCLVEAAIGTGRPHQIRIHLAAVGAPLLGDPLYRPGGGVNPGA-LPGDPGYRLHAHRLTLPWP-------------------------------------------------
>UniRef50_Q4D881(103-444:474) RNA pseudouridylate synthase, putative n=4 Tax=Trypanosoma RepID=Q4D881_TRYCR  E=1e-29 s/c=0.39 id=26% cov=80%
-IHVVHDDDAVIVCVKNGNLPVAEGGRYSGNTLVGLLERRDavsfvsekysaarqkmdqtreedgdagvsvhKVPASYYPIHRLDKETTGLVVLAKQLAAARALSRQFekqseritaqvskrtdpagdglstavfekllaEEKVVTKVYVAVLAGAGPEGAdfvmcdrigllfdslwnegdTEDAKKHNKLKKLKMACFPVNlkenpkRHGRPAASRVRILSSDKKL---------GVSVARVDILTGRTHQIRIHCAQLGYPVLGDKLYetttpgvvggccavpddtyiarakGNEGLVSAAAPRLRVKRHLLHAAVLSFLHPISEERL-------------------------------------------
>UniRef50_A4SY63(88-292:299) Pseudouridine synthase n=1 Tax=Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1 RepID=A4SY63_POLSQ  E=2e-29 s/c=0.64 id=28% cov=76%
----LYQDEHILVADKPHFLPVTPSGLYLHQTLLN-RLKKKTGIQTLSPIHRIDRDTAGLVIFSINPYERANYQNLFRDRTVTKVYEAIA--PYSKELANKLPLTYRSRLEESEHflqMQEVEGEANADTYIELLEASE--------PWARYCL---GPGSGKKHQLRCHLNALGAPIKHDQIYPVLTPYQEYDLDFSKPLQLL-AKEIAFKDPISGE---------------------------------------------
>UniRef50_B1VE82(143-420:422) Putative pseudouridylate synthase n=1 Tax=Corynebacterium urealyticum DSM 7109 RepID=B1VE82_CORU7  E=2e-29 s/c=0.47 id=34% cov=83%
-LRLLFQDANLLVVDKPPFMATLPRGQHIVETALV-RARRQFGIPELSPAHRLDRLTRGVLMFTVRPEVRGPYQRLFDERVPEKTYEAVTlpadeapfppiprfRGWqewpaptpeqpwllrhhmVKERGRLATYLVEPEAPAIDATAPTDSGaaaaspshdmflaPPNALTKVVGVrsERRALAIAGGPTPRERRVLVwELVPETGKTHQLRVALRTLGLPILNDPLYEELSDEAlrdptaalpsppfAGEEDFGRP-MELTAQRLRFHDPLTGELREF-----------------------------------------
>UniRef50_B7XJU4(78-329:331) Diaminohydroxyphosphoribosylaminopyrimidine deaminase n=1 Tax=Enterocytozoon bieneusi H348 RepID=B7XJU4_ENTBH  E=4e-29 s/c=0.52 id=26% cov=63%
-IPTIYIDDEITVVNKPFGIPCHPVGAYHYYTVTKTI----FKNKPVGCVNRLDIPVSGVLII--NTCNQKRIHEYLLNSK--KIYIAKVIGqfIFSDEQLHKLGIEKRISNGKSiiivnksllldpktKKQKISDDGKFAETHFELVSY-----------QNQYSMIKCYPITGRTHQIRVHLAYIGFPILYDTLYG------------------------------------------------------------------------------
>UniRef50_B7FPM1(1-168:168) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FPM1_PHATR  E=7e-29 s/c=0.77 id=29% cov=63%
-------DAAVYVCNKPSSVPVHPAGPFLSNSLTIM--VEAQVGLQCGslkPVHRTDRVTSGLTLCCKSSAVARIFHRCLSEGTVDKLYVARVHGKFPstnSEMHLDAAV--HTLDPANGVRIVDSAGKPSKSVFKLV---------DFNQAENVSVIACQPITGRNHQLRVHLQMLGYPIVNDTQYG------------------------------------------------------------------------------
>UniRef50_B8BW13(24-282:614) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BW13_THAPS  E=1e-25 s/c=0.46 id=31% cov=83%
--------NHIIAL-KPPSVVCHHSGWTGSRAKLkrgeepeipMLQRVREALHdigtrdlpdeqkakvRKVNLVHRLDRGASGCLLLAyADDDGAevanasvsgstAMLIDALASPESTKTYVALVRG----EGILREEDFKTKGwfNVTRPIKDESGEEKDATTWFNFVAGQPETVEDG-IERPRMSLVLARPMQGRWHQIRKHLNGISHPILGDTTHGASTVNREWKEKRNLPgeRICLHLARLQL--PPTEavpEGIDVCCPLLDDMLDML-----------------------------
>UniRef50_Q6MNN8(18-208:521) Pseudouridine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MNN8_BDEBA  E=9e-29 s/c=0.68 id=29% cov=70%
-------------VDKIAGLNTHTPEYGQRG---CVEIYEEELDRKLYTVHRLDKATSGALVFATSSEIAAQLTQAFEQHKVEKKYL-----FLTDKKIARTEFTYESFIQKEKNVFVSRDTQEpnSKTSFKWVKAL-----------GPYQLWEAVPHTGKPHQIRLHAEANGIAVLGDS-------DHNGTNHF---RLCLHSQVLGFE--LNGQKVRYETPLP------------------------------------
>UniRef50_A8Q8B1(93-263:937) Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS 7966 RepID=A8Q8B1_MALGO  E=4e-28 s/c=0.74 id=27% cov=64%
-VRILHRDDSqgrIVVV-KPGSIPVHATGRYHHHTLVEMVKEQAKL-QNLYTSNRLDRLTSGIMVCSTTKEAACELGNDFNAGLVNKAYVCRVVGRFPD-GIVDctEPILSVDRQSGLNIVHPK--GKECRTLFQRLSY---------DAATDSSVLVCRPITGRTHQIRVHAQWLGHAISNDPLY-------------------------------------------------------------------------------
>UniRef50_C5KHN4(113-290:296) Ribosomal pseudouridine synthase, putative n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5KHN4_9ALVE  E=6e-28 s/c=0.71 id=32% cov=64%
---IVFirEDSArgIVAVHKPAGLPTH-SGGKYMRTSLVHILARAFNLSTIRPINRLDRETSGVVLLAADASVHERL----KDRSlLSKV-PALCRtPIAVDRHVPNQPL-------MSRVVEDSTNSTLCTTLFRNLGN---------------GVVACRPVTGKTHQIRVHLSHLGFPIQGDTLYGGR--------STPEGRLRLHAH--------------------------------------------------------
>UniRef50_C1M2U8(543-768:875) Ribosomal pseudouridine synthase, putative n=2 Tax=Schistosoma mansoni RepID=C1M2U8_SCHMA  E=8e-28 s/c=0.56 id=28% cov=67%
--------ENVIALNKPRGIASQPGADCKHNIVDLLPRIESLIRKRnhhgkgeekyigeLSTVHRLDKDSSGIILIARNKDSALKLQEAFSRRWIKKDYLCITVGIPRSDyGYIQLPLVERNFNGIRKMCTPQLNRRlqeltckqtqldidnEAneydVTDAFTVLYDKMRTNNNQPTTwynlidkqNNAALMLCSTLTGIKHQIRAHLAFgLHTPILGDHKY-------------------------------------------------------------------------------
>UniRef50_C4QP03(45-300:370) Ribosomal pseudouridine synthase, putative n=1 Tax=Schistosoma mansoni RepID=C4QP03_SCHMA  E=8e-28 s/c=0.49 id=29% cov=67%
-LRVVHENQGFLVINK------HPELLINCTTpwincLTLQMQLFYNRPRYVnwklknmfHFVHRLDCPTSGLICIAYDTKAASMIRRAFENKEVKKYYLAIVWGYV--GSFCDSGLSSSFVKHESKLVHhiqmsigsfrylwPNTGRKQkiivPITHpecYRPRESLTTVIVLdyGKLMGEPATHILLIPETGRRHQLRVHCAiGLGHPIAGDTTY-------------------------------------------------------------------------------
>UniRef50_UPI0000E0E896(1-204:240) 23S rRNA pseudouridylate synthase n=1 Tax=Glaciecola sp. HTCC2999 RepID=UPI0000E0E896  E=3e-27 s/c=0.61 id=25% cov=77%
-MQVLYDHSDFFIIAKPQGVTMHEASNGLPAVLPLFKAALANMAypeaqyAHLHLVHRLDDHTSGCLIIAKHAVAAERFRELFSQQRIQKYYVALSHAKGKRKAGWVK--GDMVNKRKGQWVLTKSVERPAISYF-----FRQGLGNGLYLFW------VKPFSGKTHQVRVALKSNGSGILGDPQY----------SSEPAQRMYLHAFALDFI--YDDEPIQIHCPVD------------------------------------
>UniRef50_D2VX88(13-249:272) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VX88_NAEGR   E=3e-27 s/c=0.52 id=29% cov=78%
-IPIIFKSRDVLVIDKPNDLHIDGDYELTVEKLINnyypemenpLEEIQHKPGhtpsrRKLKFCHQLDYATSGILCLAFTRESCAKITYPFQQRTAQKQYLAVLRGHvLINDFEILTFIGEDPSDERKFRMRnfylgrektllselnteeeiqEAKKSRESLTFGSVLCRGFYHKDNDTIPVTK---VLLRPKTGRRHQLRLHTQLLGFPILGDATY--SLLGRDGEE--GVHRMMLHAWNLTLP---------------------------------------------------
>UniRef50_Q25346(167-402:413) Pseudouridylate synthase-like protein n=7 Tax=Trypanosomatidae RepID=Q25346_LEIMA  E=5e-27 s/c=0.52 id=22% cov=88%
---VLFKNEHVIVINKPSGVPIMPTHDPLAMNITdLLPAWRYTNTQTPVICHNLDTETSGCVVLARSANTHRMLGRMFVKRVVpNSVYWGFAVGKPP----VNFGRIRMHFEVQKGQGGDVIVARPTPTADSKVGIAEFVVNASALEFGSF--ISFYPLTTRRHQERIMAAHaLRAPLLGDAKYGGESAFPHSLSLFWDParkdvPLHLHHRKIQLPYkNGAGEFVCVTAPLPPHMEKTFKRLGW------------------------
>UniRef50_Q6F0Q2(103-303:323) 23S rRNA pseudouridine synthase n=1 Tax=Mesoplasma florum RepID=Q6F0Q2_MESFL  E=7e-27 s/c=0.61 id=24% cov=65%
-IDVIYEDSNLLIVKKPYNVEVH-SPVKTSMDDIVKNYLFDTNQYNPseensyviSHIHRLDKLTSGLIMYAKNKQTHDIMVEAIQDKEkIEKYYRCRID-VPVTESLIAKGWIKYDPIIQKSVFSEEfrSDYKEATTIFNVVS---------LDVTNEQTELEVQILTGRKHQIRATLEYYGASIINDSRY-------------------------------------------------------------------------------
>UniRef50_C4LG57(108-354:364) Pseudouridine synthase n=1 Tax=Corynebacterium kroppenstedtii DSM 44385 RepID=C4LG57_CORK4  E=1e-26 s/c=0.49 id=28% cov=82%
----------ILVVDKPPFLATMPRGRHITETATV-RLRRATGNDNLVPAHRLDRPTSGLLLFTTHPRYRGPYQTLFARRQVRKTYQAIapyhpvlaestdraeIEHVAIDSGTIsleDDGIhvhQRMEKTHGFIQARLEPGKPNAETvissirmltddDERALREGYHNWFGDPLCDTRYALYTMHPLSGKTHQLRMCLNSLGVPIVGDQVYPRILPEAIDAHQHVDeawhQPLCLRSTQLSWTDPNLHRPITVTAP--------------------------------------
>UniRef50_B8P3B5(60-229:348) Predicted protein n=1 Tax=Postia placenta Mad-698-R RepID=B8P3B5_POSPM  E=2e-26 s/c=0.71 id=33% cov=61%
----LYVDRGLLLVNKPSGLVCQYNRkddreqnAHSDFNDFTDDLKRQLsLDADLLPLHRLDKATTGALAFALTHSHAQDLAEQFNAHTVKKSYLAIVRGGTASFPNRTGNIRGVLYTTNGRVSSEAQGqwEKRAIteTDWEVLAS---------SPVAPLSLVRLSPFTGHKHQLRVHMAKI-----------------------------------------------------------------------------------------
>UniRef50_C1DA62(7-215:236) Pseudouridine synthase n=1 Tax=Laribacter hongkongensis HLHK9 RepID=C1DA62_LARHH  E=8e-26 s/c=0.57 id=30% cov=70%
------EQAAFLVIDKAPGTHVHRDG----EATGLMDRLRDDTGcDTLHLVHRLDAMTSGLLLVARSADAAAALGQALAARQVEKFYLALSDRSPRKKQGWVIGDMERSRRASWKLLPTRQD--PAVTQF-----FSAAAGDGRR------LFLLRPRTGRTHQLRVALKSLGAPIWGDPLYHPQEPGREAPD-----RGYLHSYGIGF----------------------------------------------------
>UniRef50_D2L201(87-269:313) Pseudouridine synthase n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L201_9DELT  E=8e-26 s/c=0.65 id=27% cov=70%
-VPVLVQTGDFAAVSKPAGL--HSAAIAHGGGQSLDDLLPALFPDRAAIlLSRLDRLTSGIVAVALTPGAGTRYRDLEDAGQVAKDYLAVVHGVIADPFVVDFRL-DTADRAKTRVRFKSEPDPLRHTQVEPLDRLD-----------GLTLVRCRIAKGARHQIRAHLAGAGHPLVGDPVYGRGEG----------ERLHLHCAALA-----------------------------------------------------
>UniRef50_P45614(82-278:302) Uncharacterized RNA pseudouridine synthase MCAP_0714 n=3 Tax=Mycoplasma mycoides group RepID=Y714_MYCCT  E=1e-25 s/c=0.60 id=26% cov=65%
-LDIVYEDNNILIVNKPNNLEMH-SIYNLCLDDMVKSYLVDKKEYDIYLensfvishVHRLDKLTSGLVIYAKNKISSIILTNAFKTKdQINKYYYALTSydwnlnDFLQVNGYINY---NSNTQKADFSLVEKNNYKYCQTEFKLVNKN---------------LILVKLITGKKHQIRSVLSFYNNPILNDFRYNGKKEN-------------------------------------------------------------------------
>UniRef50_D1J7I2(82-267:278) Ribosomal large subunit pseudouridine synthaseC n=1 Tax=Mycoplasma hominis ATCC 23114 RepID=D1J7I2_MYCHP  E=2e-25 s/c=0.63 id=24% cov=68%
-FKVIYEDKNLLIIDKAPNIAMHSEENCLDDQVLKYLNFKKVSSFRPASIGRIDKKTSGLVVYAKNYKTLVEFEN--KQNKFDKIYQ-FVSDF--DEDVLDITVRLKKDIKNEKMIVDNNFGVKAQTIF------------YKEGNRKFA----KIITGKKHQIRATLAYLKTPILGDIKYGGK----------FAKRMYLHSYSIKF----------------------------------------------------
>UniRef50_Q73NR9(12-259:261) Pseudouridine synthase n=1 Tax=Treponema denticola RepID=Q73NR9_TREDE  E=3e-25 s/c=0.47 id=23% cov=80%
--EVIFENEAYAVLYKPRGMPTAPLSEDEEGTLVSWFLKRcpeavsvkGKKDIEAGLVHRLDTATSGLVLMAKNQESYDALNLMQGNDLIKKTYVAFTdidneSDLNADFSRLNLPYRissqfRSFGPKGKKVLPVFYGMRDFSSTAKIYTTNIIDINNLDDSVPRVT---CTLTQGFRHQVRAHLASIGLPIYGDPLYnGKFKDFPQEKIEDHSYPLQLYAVGLSFPEP-------------------------------------------------
>UniRef50_B7FYH0(91-308:311) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FYH0_PHATR  E=4e-25 s/c=0.54 id=34% cov=74%
---ILARTDRYVVVAKPPTVVCHhsewtGSRSDPFQIPMLQRTREAMGGNCVNLVHRLNWGCSGCLLLtyaADTADAeiyipntTATLIASMKETASLKTYLALVRGEgllqgrdFKQEGwfKVDRPIKNEKGILN-----------NATTWFRFVAGQDND--SGRINQPRASLVLARPETGRWHQIRRHLNGLSHPILGDTSHGNSHVNREWRDLRGMPaqRTCLHLARLQL----------------------------------------------------
>UniRef50_Q5CTM4(125-345:481) Yd1036cp-like RluD, S4+type 1 pseudouridine synthase n=2 Tax=Cryptosporidium RepID=Q5CTM4_CRYPV  E=5e-25 s/c=0.53 id=26% cov=69%
-VKILYDSSTLLAVFKPCGIPCHPqGRFNKLSLTKLIQSEYlsklNTNSTYIHPINRLDRVTSGLVLLSKDSSTTKNLSSkvQFA----HKYYLAMInestsnfishisqssiegvsirelsldesHGITSHVIKCEIGLKTLKDREGEsliTRIDSSENSKYSLTYFFPLIScldINEAKKQKINETDKYSILLCKPITGRTHQIRAHLKYIGFPIVRDILYSDK----------------------------------------------------------------------------
>UniRef50_B7G4K5(55-405:418) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G4K5_PHATR  E=1e-24 s/c=0.33 id=29% cov=82%
---VVYETDHFLALNKPPDLRMdghHPSTVLKlltywypppafqnlqskglLEKVSEFENYRNIEGNELRPCHQLDYATSGILLVARNRQAADQARVSFEERSTRKTYLALVHGHLsvpsnipvMRRTDIDERMGRLEEIYRQSRRKHRKdtyrGYQPAHGLFQQLQQqhnhilnlswkevkasgktepfdraaevfnkLQYKTLFPEDKSAELSLptffrdesedpntlfiyasvaqvphdfamrinpsmsnasaylkvgdssldykpsltrcvilkhaairgqpvtkVRLEPRTGRRHQLRVHSALLGHAIVGDQTY------KAPGSPDLTDRMCLHSQCLEI--PLFEELIKVEAPDP------------------------------------
>UniRef50_A6GFD8(92-332:401) Pseudouridine synthase, RluD n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6GFD8_9DELT  E=1e-24 s/c=0.48 id=33% cov=70%
-LEVLAETPDFVYVHKPAG--VHTVALTPQQPGVLATAVAERWPECAgasedpregGAVHRLDRPTSGVVAFARSPEIWARARKAFSAEQVRKRYLAVCldlgarergaamtwppalpegglRGWVLPAEVEAHPRAElgslagidtatathPSFRVRAPLGRVAREAEiPSHTAVRLDGQRASSVVHPLAQASATStgaqpwLLALELETGRRHQARCHLAWIGLPIVGDSLYGPR----------------------------------------------------------------------------
>UniRef50_C1E520(58-368:372) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E520_9CHLO   E=6e-24 s/c=0.36 id=28% cov=91%
---VLYVDprARFFVVNKPAGMYVenvldfierymeevrraperHserskRAKTCSDGATSIREAFdsLAKVGERFQLLHRLDRDTTGCLGIACDKETNRILSRAFQEGRVKKHYVAHCINTKFADDfqkkwkdwEVDEPFedgsramtwpqrfcnfrlechtghGRSKHGLWRLYAKEDVGrelpggskVKEARTNlYRGFDSDSDSKRLAHLRELQSFPVVAEPITGRTHQIRMHCSQY-FPIVGDYKYGyDDTADDDVVQEEREKGYRLHSFSLELPikIPDGNgfRDTLVLAPPPSWWNE--EEWGTYDILME------------------
>UniRef50_B6AH65(140-394:527) RNA pseudouridylate synthase family protein n=1 Tax=Cryptosporidium muris RN66 RepID=B6AH65_9CRYT  E=7e-24 s/c=0.44 id=27% cov=68%
---ILYNNKHFLAVYKPYGIPCHPqGRFHKlsLTNIVMSKYFRSETeviidnkaasriinddKLYAHPINRLDRVTSGLVILSKNCDSTRLLSKVIS--KSHKYYLAHVEGDFSSLEHVDigklfkstqlvkiqnlemglninfgikceAPLEIIKDRVGDSLMTKVsfENGKSALTWFFPLKIEYLSQEDRKKIKLDqvnfesinichkpNSYVLCKPVTGRTHQIRAHLQYLGFPVTLDHLY-------------------------------------------------------------------------------
>UniRef50_Q6KHG9(110-310:314) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Mycoplasma mobile RepID=Q6KHG9_MYCMO  E=7e-24 s/c=0.56 id=29% cov=68%
-LEIIFENLDILIINKPNNLIMHSSKNSLDEQ--VLNYLNYVKIDSFVPTHigRLDKETSGLVVYAKNYKTLIELLD--KQSDFEKIYTFIPFCNLSEKDVlVTVNISEDE---INKKMQISNEGKKSITR------IFYDGNSQRYY--------AQILTGRKHQIRLVLAdFLKCPILGERKYANLTKDK---------RLFLHSYKLTF----------------------------------------------------
>UniRef50_C4XKF0(88-262:290) Putative pseudouridine synthase n=1 Tax=Desulfovibrio magneticus RS-1 RepID=C4XKF0_DESMR  E=5e-23 s/c=0.63 id=27% cov=65%
---------DYVLLNKPSGL--HSAALAQGGGESVEALLPDIFPGRPsFLLSRLDSLTTGLLPAAFSPEAAATYRDMEESGEVDKTYLAVGHGEPdvtyfRCDGELDAADRKKTRVLDRA----------------TIDSLRMTEVEALETRGGVTLFRCTIKKGARHQIRTHLAWAGHPLVGDPLYGQGEG----------ERLFLHCA--------------------------------------------------------
>UniRef50_D2VJR9(62-262:301) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VJR9_NAEGR   E=9e-23 s/c=0.54 id=32% cov=60%
--------------------------------------------------HRLDMATSGVLCLSMTRESCACLSTSFEDKTSRKFYLALLSGDVNleelkmneklrnnvkvvnendcSKIIITSFIGRddggnneneeyDPTGRGFVMKQTLEKPIEDLSKYKTKQERQqhqfregtsemIILSYGQVENKPVTKVLLRPLSGRKHQLRLHSLLLGHAIIGDEMYG---------ENDGFSRLMLHAYSLQI--PIDKEYL-------------------------------------------
>UniRef50_B3L648(66-243:504) Ribosomal large subunit pseudouridylate synthase, putative n=6 Tax=Plasmodium RepID=B3L648_PLAKH  E=1e-22 s/c=0.61 id=28% cov=67%
-LSIIYENEFFLVVNKPYDIKLEKGKLD-DVYPSVETLLRQKTNLDVFrICGQLDYATSGLLIIAKDKLSCNILNYNIESKRISKIYLAILYGHLPLGVLhVNTPISKIKNNFKMKlcynYNDYYDTGKYC-------YSLIYPYKQCYLKNQKVTLCELRTITGRRHQLRLHALCLGSGIVGDETY-------------------------------------------------------------------------------
>UniRef50_C3JBT0(88-322:330) Ribosomal large subunit pseudouridine synthase family protein n=2 Tax=Bacteria RepID=C3JBT0_9PORP  E=2e-22 s/c=0.46 id=22% cov=90%
-VKVLWQDDWFILVQKEPGIPTIASkPGDRHTVyrIVADHYKSGDAREKIFLLNRLDRDTRGLILFARDREVQQEILDNWEKYILSQTFSALVEGVVPEEKGEFAPPPKPKKTVGDKDTKKKV----------VVSRRSRATYLVEERGQWRTLLRISLL-GRYNGIRSQLNEKKYPLVG-----ESKGVIKGAPSIALSQQ-----ELVLLHPITKEKLRFESPIPSFFYKLLRR-----RLTTSERKIIEKRTESENDLS-
>UniRef50_C2HWY8(14-116:177) Pseudouridine synthase n=2 Tax=Vibrio cholerae RepID=C2HWY8_VIBCH   E=2e-22 s/c=1.05 id=31% cov=40%
-IDVIYEDEHIIAANKPSGLLSVPGR--PVEHYDSMWARLVDYCPDVKVVHRLDMSTSGLILFAKGKHMESALKKQFQYRLTHKIYYARVWGVMEqDEGEVNLPIV-----------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5J5W4(82-262:284) Ribosomal large subunit pseudouridine synthase n=1 Tax=Mycoplasma conjunctivae HRC/581 RepID=C5J5W4_MYCCR  E=7e-22 s/c=0.59 id=25% cov=62%
-FDILYEDSNILVVIKPRQTAMH---SHKFSLDNQVHKYLNIKMADIFkPAHigRLDKDTTGIVIYAKNYQTALEMNK--KQHFFVKRY--VFKSDIDLKEKVDVKLWIKKNDDLKKMEVSQEKTQNSQLAITSLFLIGNNKI-------------AQLQTGKKHQIRLTLSHLGYPIYGDQKY-------------------------------------------------------------------------------
>UniRef50_B2RHT4(87-304:324) Probable RNA pseudouridylate synthase n=1 Tax=Porphyromonas gingivalis ATCC 33277 RepID=B2RHT4_PORG3  E=2e-21 s/c=0.48 id=26% cov=79%
LVRIIWQDDYFVLIEKKAGVSTVASGVNKDRT--ALRIVSDHLKQYdpevkIFMLNRLDKDSAGMVLFAKNKEVQGFVVDKwskvvLEQRFV----MAI-EGEMPDaEGTLDPPRYQTSIKGKQSRIVAETPSVHSVgtARYKVIRR-----------GAVCSLVEVTLLSGRNNQLRRQMGQLGIPIAGD--------WRQGSSFRHLDCLALQGTRFVFRHPETGDTQEYKLPLPKLFRRLI-----------------------------
>UniRef50_Q4Q7A0(209-500:533) RNA pseudouridylate synthase-like protein n=3 Tax=Leishmania RepID=Q4Q7A0_LEIMA  E=2e-21 s/c=0.36 id=31% cov=52%
----------------------------------------------LFTVQRLDKETSGVVVLAKNSVSARTLASQLEAQTkgcadavesrlrerghavalssdafdellrlkaqsVHKTYTAVLRGAAPEDHTfvvvncMDC-MAKHPTHSWEaqhtqlkklkmccepvkemlfshAAAALPQSPKEQQTRWGRLAVTRIRVLASNKKLG-LTCVQVELLTGRSHQIRLHCAAVGYPVLGDKLY-------------------------------------------------------------------------------
>UniRef50_C6BZC7(118-291:302) Pseudouridine synthase n=1 Tax=Desulfovibrio salexigens DSM 2638 RepID=C6BZC7_DESAD  E=4e-21 s/c=0.60 id=26% cov=67%
-------------VYKPEGL--HSAAIAGSAESSVEECLSGiFPGKEPILANRLDFLTSGMLLIAFGVERENEFRECEDSGTVDKVYHAKVHGIPEGPFVVKNSL--DTADRKRTKVLDDQAPEERWSSAEVVERYDDGT----------SLLEVRIAKGARHQIRAHLAHAGFPIVGDPIYG---------REDSADRMYLHHRKIVLP---------------------------------------------------
>UniRef50_Q4A6V6(82-260:281) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Mycoplasma synoviae 53 RepID=Q4A6V6_MYCS5  E=5e-21 s/c=0.58 id=22% cov=67%
-FQIIYEDANILIIDKKENLVIH-GEDNSLDNQVLSYLKHKQIDSfKPSHVGRLDKETSGLIVYAKNYLTLKQLNE--KSFNFKKVY------QFKSDFLSSSPLelklyfYKDENNKTKISKTQKENSKLAHSIFYCENNKKF----------------AQIITGRKHQIRLSLAYLNKPI----------YGDKKYKGKKSTRLMLHSYYLKF----------------------------------------------------
>UniRef50_C1EHD0(185-468:481) RNA pseudouridylate synthase n=1 Tax=Micromonas sp. RCC299 RepID=C1EHD0_9CHLO  E=6e-21 s/c=0.36 id=27% cov=68%
---VVHEDDAILVVNKPHRLPSmaHESNGVEHCAGCLERSL-GLSPSTLRVTHRLDSSTSGVLVLGKTATAVREFNDSVAktpgSKEIVKSYAALVyakhavplglmthwmypgpfgpgafHGRTLRRSRARLvrssadgergddtggqGTGKRWKRCELRVVSCDRATQSQVDTWRTLFDRELERARkpfdggaddplvsggdspgGDSPGASVWAVRVELVTGRTHQVRAQLAAAGAPLLGDSLY-------------------------------------------------------------------------------
>UniRef50_B6W881(84-188:195) Pseudouridine synthase n=2 Tax=Bacteria RepID=B6W881_9FIRM   E=1e-20 s/c=0.97 id=28% cov=37%
-LDIIYEDENIIIIDKKSGVLSHAASSSDYGKNLVDQMTSYLYKTnkvnsrdltfRPSIVNRLDRNTAGLIIGAKNAKSLRALNEAIRQGKIYKYYLTLVEGEIKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q313X0(85-274:305) Pseudouridylate synthases 23S RNA-specific-like n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. G20 RepID=Q313X0_DESDG  E=1e-20 s/c=0.54 id=27% cov=66%
--EVLCRTADYAAIFKPEGL--HSARIAASPAPSVEDQLDSLFAGEtpPVLVNRLDRPTSGMVLAAFGSHAAEAFRKFEQAGQVEKLYLAVVLGHMK------APVACRNELNMQNRQVTTVLPHEAqdpLRHTTVLPLRALPAES--MDGQKTTLVLAAIHRGARHQIRAHLAHAGHPIAGDCVYG------------------------------------------------------------------------------
>UniRef50_B0W634(12-278:493) Ribosomal pseudouridine synthase n=1 Tax=Culex quinquefasciatus RepID=B0W634_CULQU  E=1e-20 s/c=0.38 id=31% cov=62%
---------------------VHPCGRYRHNT-VVFILAKEYNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEHQIRNRQVQKEYICRVEGEFPESSPVsnsaNHPaaapaqqqrehtssrssrgkrrrssprtallvvaarhQAKHEDEERERTLGGDPSPHRPVKKGGSLnhhtRTAENSLTSNALPRSKRCLVAgggtaddellgmgsntldgiieckepievvsykigvckvspkgkectttfqklgyngsssvvlCKPLTGRMHQIRVHLQYLGYPVVNDPLY-------------------------------------------------------------------------------
>UniRef50_C1DZS3(249-445:474) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1DZS3_9CHLO   E=2e-20 s/c=0.52 id=27% cov=61%
--------------------------------------------------HRLDVATSGVLVLARRSSFAAEFNDALRRRRVTKTYECVTAravpvGVLEHwteesSGAREGPARfemRELEPGDPRWRDVAADGKYSDDAFvtpdgrklcvlRVLGCEETEGLTKRltkrlageageAGEASRAYVStIELVTGRTHQIRAQLSAIGCPILGDVLYGGVDLSREGGATPRVlrddDRLCLHAAEMR-----------------------------------------------------
>UniRef50_B7G1Q0(180-423:607) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G1Q0_PHATR  E=5e-20 s/c=0.41 id=24% cov=79%
---IVAEDTDkgWLVIRKPSMVPVHMTVDNcRENVADCLKQARawqsptaDARDVYITTPQRLDQNTSGLVVVATHKPFAAYFASLLRSKTarqlsgdgddrnheslgsVHKLYRCLpsirapkrfVEHPPDDTQWPECLLKIVKVGNVCELVGSPAGQDLA----EALWQDASGQAKRIPPQAKAVVeVEIELLTGRTHQIRGQLSTLGFPLVGDAQYGGAVPRNPTNEQFyiGTEQLALQCCELAFRDP-------------------------------------------------
>UniRef50_UPI0000E499FC(85-361:373) PREDICTED: similar to RNA pseudouridylate synthase domain containing 3 n=1 Tax=Strongylocentrotus purpuratus RepID=UPI0000E499FC  E=5e-20 s/c=0.36 id=26% cov=87%
--NIVYQQDGIVAINKPPGLGVSGkvnedDESSPLTLSSMMSQVADFTDcPSAEIAQGLEKEASGLLLLAENRMAAKKLQSKIKEarnrRQFIKTYRSIVCGIPETKigvskmylgsdviGGINMTVGRHNPSGRQ---IRDGDVWSAETKYRVISENKEL---------GCAFIELQPLRVKRHQLQVQMVNDLCPILGDHTYSHQVQTILGKPILMDPHQALgvHNIQvlspgirkaLAMTRPqvsllplflhlhhvvlpewAGHQDVTITAPLPSHFTRALKELGLRS----------------------
>UniRef50_A3BN26-2(136-317:400) Isoform 2 of RNA pseudourine synthase 6, chloroplastic n=2 Tax=Poaceae RepID=A3BN26-2  E=7e-20 s/c=0.55 id=19% cov=67%
--------DNYVVLDKPAATSVGGATDNIEESCVVFTSRALGLETPLMTTHQIDNCSEGCVVLSKTKEFCSVFHGMIREKQVNKRYLALTT-APVSTGIITHymrPINRAPRLVSEDHIKGWHVCQMEILDCKkvpwpssLIRKVHKVDNCGWPQQEAAYECKINLLTGKTHQIRAQLAAIGTPIVGDSAY-------------------------------------------------------------------------------
>UniRef50_D0N5S3(116-200:214) Putative uncharacterized protein n=1 Tax=Phytophthora infestans T30-4 RepID=D0N5S3_PHYIN  E=1e-19 s/c=1.17 id=29% cov=33%
---VVYQDAQFVVLNKPHGLAVQDGSTLTESLALYLPWIAEQ---QLRLVHRLDKETSGVLVLARSRLAAAKFSKLLRNGAVYKTYEALVE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2V6I3(132-241:279) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2V6I3_NAEGR   E=5e-19 s/c=0.88 id=33% cov=36%
-LEIIKEENDFVVVTKPPGICVHP--IKRYHKNSLFYMLEHEYAHHFGndlhckTIHRLDKETCGVLIVGKTSEGAKYFQKLLKEKQVEKQYIARVDGIVK---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5A0Y2(14-221:247) Pseudouridylate synthase PUS5 n=4 Tax=Candida RepID=PUS5_CANAL   E=5e-19 s/c=0.47 id=22% cov=68%
------------VVNKPSGMVCdasHTNNIITALTNEFTKILPSVNSSQFRLVQRLDRFVTGGLVVARNKKWADKVRKSfFQEGTLRltRRYVGLIAlDQIPEstQGTIDFPIQALEKDYRGKNKSRELFTYSAVTHYKLIpsARRTIKGVFPVFQQGPILPIILELETGRKNQIRDHiIQKFGVPLLNDDNFSDFKLN-------------------------------------------------------------------------
>UniRef50_Q9SVS0(216-397:472) RNA pseudourine synthase 6, chloroplastic n=8 Tax=Embryophyta RepID=PUS6_ARATH  E=6e-19 s/c=0.53 id=19% cov=66%
--------DSYVILDKPAGTTVGGTTDNIEESCATFASRALDLPEPLKTTHQIDNCTEGCVVFARTKEYCSVFHTKIRNKEVKKLYRALAA-APLPIGIISHYM--RPKNMAPRLVAEDSIQGWHLCQLEVLECKKIPWPDAatekKHDIEDCGWtskefaYECTinLLTGKTHQIRAQLAACGAPLVGDSMY-------------------------------------------------------------------------------
>UniRef50_C1MNL7(210-464:548) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MNL7_9CHLO  E=6e-19 s/c=0.38 id=31% cov=69%
---VVYEDEETLAVNKPHALPTqaHESNAAECVPGCVARALGFTGgvtdGDDALLVtHRLDASTSGVVVLGKTLGAVRAFNASIAgGKRVTKTYVALVenasnvrrRGVTVEDATTPPPPvplgrfvhymypgpfgasalggrgaRRSNARLLRRRAPsaSDGDAKPwrrcelvvrscarasprdvaawralfAESvegnanweAARGVDDGSRDEPSRRAGDDAVYEVEIELVTGRTHQVRAQLAALGFPILGDTLY-------------------------------------------------------------------------------
>UniRef50_Q9U190(1168-1446:1469) Possible RNA pseudouridylate synthase n=3 Tax=Leishmania RepID=Q9U190_LEIMA  E=1e-18 s/c=0.34 id=28% cov=68%
-----------------------------------------------GLVNRVDVGTSGVVLVARTADAlHGAADAMIREHHMRKTYRALVQRWPPfsssssssastvrydddnaaaaplfsvspflspmPSAVVCAPvyaagatassisrrsalplshgrqLQSPGQPSADALAASRAGStlswsssvpvslsslehvhqqyatlhaalqdqRNAITRYRVLEY---------FASAGVAYVQVELCSGRRHQIRQHFAQLGFPLVGDARYHAGVVAGHAGTTLGMRRAALHAYTVDILATTDGddlasseevpDRVVVQAALPADMHRAL-----------------------------
>UniRef50_C6PYN7(103-173:173) RNA-binding S4 domain protein (Fragment) n=1 Tax=Clostridium carboxidivorans P7 RepID=C6PYN7_9CLOT  E=2e-18 s/c=1.35 id=26% cov=27%
-IDVVYEDSDLIVVNKQPGMVVHPTKSYPNGTLAngLLYYFKEKGEQCiVRLVSRLDMDTSGLIIIAKNQFA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0NJP5(65-425:458) RNA pseudouridylate synthase-like protein n=1 Tax=Phytophthora infestans T30-4 RepID=D0NJP5_PHYIN  E=2e-18 s/c=0.26 id=33% cov=75%
-LRVLSRDEHFVVLNKGPDV---RMDGAFDVTLEKALARDFPQVEKFRWIHQLDFATSGVLVVGVNKDATATGCRLFREKQVQKEYLAVVRGHLPfnpaesvdtaalpakactfsklglliqdmeemerlrnqqrgsraHQKTPGYPRGVRHGPNLFTMeqaqllpeARELTPAELAFTKmtwhdltkeekgaytekakadkrrflkefseflnqekirlarkrkyesfdgedseeanepvayvfdapviephrstgvFRMLVGTETDTAAKQSTTMCFVLghaiykgepvtkVLLRPLNGRRHQLRLHMAHHGFPIAGDVTYG--------SQEDEAPRMMLHAWRI------------------------------------------------------
>UniRef50_C1MJ36(166-457:483) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MJ36_9CHLO  E=4e-18 s/c=0.32 id=29% cov=67%
--------DAFVVVDKPAGVNV--GFTVDNAKECVAQCVARALGDafaengsdssstdsstecsswgwadaTPLIVtHRLDAATSGVLVLARDVEFARHFNDALRERKVQKTYACVsearvpvgvmehwtdpedaTRGprrhVMRPPREGDTPWEERGGGGGETSTsiaeeraekaaattskqkksqrqkkrerrlakaeefVHPDGRRRCVLRVLTCEEVKIPGEKAGDAPPRYeSTVE--LVTGRTHQIRAQFAASGAPLLGDVLYGGAR---------------------------------------------------------------------------
>UniRef50_UPI000185C39D(45-298:317) RNA pseudouridine synthase family protein n=1 Tax=Corynebacterium amycolatum SK46 RepID=UPI000185C39D  E=1e-17 s/c=0.37 id=24% cov=75%
--------DEFLVVDKPPFLP--ATPNGRIVANTVQERLRRSLGEsEIVAVHRldlltsgllll-----------SRNPATRARYQQLFQNQEITKEYECLTVMpddwHVGETRDVTLLLDPNPAGRGVKVVETDVSARAAAKNpkfklARTTVTFLGPVAADIGDvlassrgggsgggatsasiplhavgcgcghcgsSMQVGYWRLQPHTGRTHQLRVTMDWLGYPILGEDTYGREAGAQGPSASAGsaptyTPQLRLTATALAFVDPVTGER--------------------------------------------
>UniRef50_Q57VS4(184-573:638) Putative uncharacterized protein n=2 Tax=Trypanosoma brucei RepID=Q57VS4_9TRYP  E=1e-17 s/c=0.24 id=30% cov=66%
----------ILVVHKPAGLPTHASGryfmnsctamleyvlaprrlhawlvekdpllqslvstihlTGRERDELLAYYLTDSMEEDtvpierlPRPCHRLDKVTSGVLLLGISKVAARRVGEALMSKtrqmeeilprrsrfesdegtitfdklhmsgaTVRKRYLARVRGCFPEnsmkirfencpgdknkegvladsnekdttcpinggllivtknshEGRRDATDGMNVKTFVNSVGVPvlftsplrqyrfsenetiyedlnesygtpikEMFCQDAMTLCQPLRHYQSDHSHHKDAGTNTeSLVHCVPFSGRMHQIRIHLSDWGHPIVGDVTY-------------------------------------------------------------------------------
>UniRef50_Q6FS81(5-174:223) Pseudouridylate synthase PUS5 n=1 Tax=Candida glabrata RepID=PUS5_CANGA  E=1e-17 s/c=0.54 id=29% cov=56%
-LKVVYDGMHYMIVYKSAGVLSQPG-LASDSRPVLMSELRGLLSEtlDLYSVQRLDACVTGGTVVAKNKRAAMMFSRYLKQGggsgyGLTRRYLARINAQPVcDEGTIESPGM--------------------VTYYRRVR-------------DDCVVVELK--TGKKHQIRKHLAlNLNCPIVNDTYYG------------------------------------------------------------------------------
>UniRef50_B8LDC7(264-595:686) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LDC7_THAPS  E=1e-17 s/c=0.28 id=23% cov=69%
---IVARDDDagYLIINKPPSTPVHArvdnlvenvassvgrmfwmerresilnqlhddvdRAGEYDDGQATKRKRRKQKIEQLVYVatpQRLDQNTSGLLVVASKKSFASYFAKLLRTKTsgqlvtcriesksdanaeekyyrssscgVHKTYRCLVCVMPSKSSSADDTSIKSMKSEVERLRKYSRE-RTVVRHFlepsirapkaffstvpkdvynpeswaecllRITNVSDICTVVGNKPSDELAVslwgesgkpdecvavveLEVELLTGRTHQIRGQLAAEGFPLVGDAQYGG-----------------------------------------------------------------------------
>UniRef50_D0NFN0(180-285:335) RNA pseudouridylate synthase, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0NFN0_PHYIN  E=3e-17 s/c=0.86 id=31% cov=35%
------ETDELMVVDKPSGIPVHPTGSFQLNSLTHMlirdrreALIEETEALKLFPVHRLDRLTSGLLILAKSADKARSLTAELTatsseggigSRSVQKYYVARVKGKFPD--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8X3G8(89-280:285) Pseudouridine synthase n=1 Tax=Desulfohalobium retbaense DSM 5692 RepID=C8X3G8_DESRD  E=5e-17 s/c=0.47 id=31% cov=63%
--------NALAAVFKPGN--VHCEAQSHNPEPSVESVLPNLFPrQRPRLLNRLDYPTSGLVLVALSQGAFDQYQIWQDEGRVRKTYWAEIHGEWTGPELLKWRIETAKRKRVAVVFEPDPDPLR-WTHVRAL----YRIAPGR------TRVEVVIAKGRRHHIRAHLAAAGTPIQGDSLYGE-----------------------------------------------------------------------------
>UniRef50_UPI0000E4872B(1-124:143) PREDICTED: hypothetical protein, partial n=1 Tax=Strongylocentrotus purpuratus RepID=UPI0000E4872B  E=5e-17 s/c=0.73 id=28% cov=48%
-----------------------------------------------------------------------------------------VRGHVTEDTmMIEKAIYPNPEEDLSHMMKVDDGECPTGTRLLSALTRLEVLQRGEYDSEPATKLLLQLHTGRRHQLRIHCQSIGHPIVGDYTY-------SMRKDVSPYRMMLLAHTLHIPIP--GEGIDVTA---------------------------------------
>UniRef50_C2MA71(89-303:341) Ribosomal large subunit pseudouridine synthase family protein n=1 Tax=Porphyromonas uenonis 60-3 RepID=C2MA71_9PORP  E=5e-17 s/c=0.42 id=25% cov=78%
LIEELYRDEQFIVLHKRPGIPtisVGGASKSSLFQVVTHHLKKVDPNEKIFLLNRLDRDTEGIIIVARDRQLQQDLLAEWHSFVLFNSFEAVVLGALdTSSGELTTRPTKDKKRGSDKRRTSTSSGrdkKPASFRasYEVLST-----------GPYITRLSLSLLT-RNNSIRSTLASIGHPLLGD-----HRANDSIAPDLS-KYLALRATELAIFHPIKRQKMLFT----------------------------------------
>UniRef50_C4R5D7(6-229:249) Putative uncharacterized protein n=1 Tax=Pichia pastoris GS115 RepID=C4R5D7_PICPG  E=2e-16 s/c=0.40 id=26% cov=60%
-----FEGPGFLVINKPPGIYTQPPSfrqGNRDKSNELLPLLEKQLQTTLRQVQRLDYETTGGLVVSTNKYTARMFHRNMQalsnnildgRHRssnkgyiLTKRYIAL--------------LNKPVTSIYEQLPKTSDG-------WRLLETQDIDesnsssklllskvrtIESCRPMHDKFPLM-FELITGRKHQIRRQIKQVfGTTIVNDVKYG------------------------------------------------------------------------------
>UniRef50_Q4Q7F2(1-426:453) Putative uncharacterized protein n=3 Tax=Leishmania RepID=Q4Q7F2_LEIMA  E=1e-15 s/c=0.20 id=31% cov=90%
----------MLVVNKPPGILMDGDESIYGRTVESLvcehmkaRGIFDETHEQLQKekkrkkqlkfVHQLDFGTSGVLCLAFTKDMAARLAHCFEMRLVRKYYVALLHGHLPSDTAlledaassdqpgsafssdtkarrasfaawanacnkaweglgcvragcsasasggssansaggdevagfrhllqrpdktaweavglanskdaeegepvtvvhryrshrspasslitvapensapvpadavedliyrtllestttcsvvfVDLPVGYDlTDPEHLRMAVTAEQSRDAKTSLLVLKRTYLaapPPAGGEVPQRGaiakdspsvtsypVTLVLLAPHTGRRHQLRVHCRAIGFPIVGDTSYCadlpwctalPLGSSPSTWVTAGARRMYLHAWRLLL--PGTATP-----CLDEVERVVLKKKRRREVLGlsEQRGVSLSA----------
>UniRef50_B8DKC4(232-433:463) Pseudouridine synthase n=1 Tax=Desulfovibrio vulgaris str. 'Miyazaki F' RepID=B8DKC4_DESVM  E=4e-15 s/c=0.42 id=31% cov=53%
----------------------------------------------PRLLNRLDGPTSGILLAARAPQAAQRFHAAENSGQATKTYIALVHGVLAQPMKVRRGLdtANRATTRVLPQDTPDALRHTMVTPLGIMQTTDIPDAAPCTPTlagdagqdsapasactthapgpactsgTPCTLVRCVIRKGARHQIRAHLAVLGHPIVGDTRYG------------------------------------------------------------------------------
>UniRef50_C3XHK3(100-193:671) Pseudouridine synthase n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XHK3_9HELI  E=2e-14 s/c=0.87 id=28% cov=36%
---------YFCVFNKPSKLLTHP--KNLADSKSILDSLRYYFGKHANPCHRLDYETSGLLVCSIDKQSEVMLKNLFLQKGVEKSYMAILHGEVKESLLIESGI------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4D992(539-661:682) Putative uncharacterized protein n=1 Tax=Trypanosoma cruzi RepID=Q4D992_TRYCR  E=2e-13 s/c=0.64 id=32% cov=29%
-----------------------------------------------------------------------------------------------------------------------------------------------------SVVECLLLTGRTHQVRVHLASLGHPIRGDKKYirlaadspsiplrtdlrdeeeeDEEEEEEESKGYLSSHGIFLHAWRYTLRYAAGEAPEVLEAPPP------------------------------------
>UniRef50_D2V9L8(190-561:579) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2V9L8_NAEGR   E=4e-13 s/c=0.21 id=26% cov=89%
-IHVLYEDKDVIVVNKPVGYAVH-SSKSKPESETMIYAIRNYvlskekekekskkkskqttntLPLNINLAHRMESQMSGVLICGKNSHSIQKLSEQFLPNTnLQKQYITVCavpninslkkklnpfyhlkeefdedeettddeegsnlsekdilssfgvskkpdrfadlnlgeaeelfvddYGDMEEDGDEELDLlegmgeehetldlsggwkdmRKEHEMLKEKYEKATKNTtltlegdlkfvmhpeynvqvlQRAGTHElpstKVLRNIKTVVNVlELNEDNRIALATVSIPSGSVQQVRSHLATNGIPMLGDFPYFDQVDNRIPiglSKNLNVNKIFFHLYKIVFQHPTSGKNVIVKAPLMSPMKEFVEK---------------------------
>UniRef50_Q4DAY9(171-492:665) Putative uncharacterized protein n=2 Tax=Trypanosoma cruzi RepID=Q4DAY9_TRYCR  E=1e-12 s/c=0.24 id=32% cov=65%
----------LLVIHKPAGVPTHAGGRYFMNSCTAMLeyvlapkRLRAWLLQRdpmlqsivstryltetecqellayymvkdegsmaeyvsierlPRPCYRLDKVTSGVLLLGVSQAATRRVGEALTRKTkqmeevflwklrliasddkkttrvggvhsieertlrefnvgVRKRYLARVHGYFPNDashalhscrvrkenagdgdhrttekvffitiptnptirrcdavkeealGVVGPPVLlasrlmqfkfRDGDTTEEPPARDQEGKQQREPFYQDAATFCQPlryfTSGSGQASEGESLVHCVPFSGRMHQIRMHLSDWGHPIIGD----------------------------------------------------------------------------------
>UniRef50_D0ND20(111-263:263) Putative uncharacterized protein n=1 Tax=Phytophthora infestans T30-4 RepID=D0ND20_PHYIN  E=2e-12 s/c=0.49 id=30% cov=36%
-LRVVYECSILALVVKPVGIHV-KGRGKRTVEQALPLLLRKQHVDAgdfelplPHAVHRLDYRVGGLLLVAKTRKMEVKLSAQFERHSVAKQYRAILVGNV----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9ZNY1(371-713:727) Putative uncharacterized protein n=2 Tax=Trypanosoma brucei RepID=C9ZNY1_TRYBG  E=2e-12 s/c=0.22 id=34% cov=69%
---------------------------------------------KVYVVHRLDSGTSGVLLFGLDSTSARMTAELLSQKddkdvaEISpsdgvvanstastkelgctKQYLARVHGHFDAAKIaedqhncslvsythssqrnacnsgsvgwlcIDRPIGcysyhdslywcpgaaqinswleerekngmvessernhkeseetserpspirgkrpkykntDELEAKHTRMKKLTIGLRGAhltgeETDYdegniecqtstgerqlrETLKRATTLVRRWSYDEDlDESVVECVLLTGRTHQVRVHLASVGHPIVDDHKYiyhlsrntpftGNYRKEVKSRlppypstiphvasncSSVTTQGIFLHAWRYTLQYKNSETPETLEAPLP------------------------------------
>UniRef50_B8J2T9(245-401:493) Pseudouridine synthase n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 RepID=B8J2T9_DESDA  E=3e-12 s/c=0.48 id=31% cov=50%
---------------------------------------------------RLDFGTSGLLCAALSTSAAEDFRAAEAAGLCEKRYVALLSGVLSGPVVARQEL--DVSKRRKSRVLPALAHHTRWTEFWPLhvwrpgdvsvqalqallgpagggapendAPVVTPEAGGlPVPAAGLTLAACRIRRGARHQIRAHAAGLGHPLWGDSLY-------------------------------------------------------------------------------
>UniRef50_B8BYZ7(69-204:571) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BYZ7_THAPS  E=2e-11 s/c=0.53 id=30% cov=34%
---VVYQDDNYLVINKPPDLrmdgpylaSVHklllylfpppslRGPSqeggggdvegdstdinttsnlqldHRHHTQLLqaiapLSKHSSLRDDPFRIVHQLDYATSGVLLYAKNRKAAGKACISFQERKTDKQYVAIV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3KZ50(120-219:230) SJCHGC01105 protein (Fragment) n=1 Tax=Schistosoma japonicum RepID=Q3KZ50_SCHJA  E=2e-11 s/c=0.72 id=28% cov=34%
-LRVVHEEQGFVVINK------HPelliNCTNPWVNCLTLQmQLFYNRPQYVnwklknmfHFVHRLDCPTSGLICIAYDTKVASMIRRAFEKREVTKYYLAIVRGYV----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C2D7I2(84-245:285) Pseudouridine synthase n=1 Tax=Atopobium vaginae DSM 15829 RepID=C2D7I2_9ACTN  E=9e-11 s/c=0.43 id=29% cov=62%
--------DHVyLLLNKPSQVLT--TMSDPFGFPCVASLVPCDDYPGLFPVGRLDSDTTGVLLFTTNGNMGNRL--LHPSHHVWKTYVALIEGKLTSSQMqkLSQGIMLEDGMTSPCFIRTITQDEPC-TH---LDKNHSLFDDMRLNAAS-SLCELKIHEGRNHQVKRMLQEIGHPVI------------------------------------------------------------------------------------
>UniRef50_Q6CQC4(42-247:299) Pseudouridylate synthase PUS5 n=1 Tax=Kluyveromyces lactis RepID=PUS5_KLULA  E=1e-10 s/c=0.34 id=26% cov=57%
----LWRDKHHVIFNKPPLALSQlpdkRTWYNTHDYDppVLLDIVQSSSGSILkdgtyepsyYPIHRIDTPVSGGIVYAVNKQSAQQFSRNLRYGgnkgfSLTRKYVAKV-GKSKTANECKEGLIKWNG---------------AITYFQRVDNEHLI---------------LQLVTGKKHQIRkltqqV----LDSPIYNDLKYGGKK---------------------------------------------------------------------------
>UniRef50_C7MNA2(113-251:296) Pseudouridine synthase n=1 Tax=Cryptobacterium curtum DSM 15641 RepID=C7MNA2_CRYCD  E=1e-10 s/c=0.50 id=25% cov=52%
-----------LALNKPAGIIT--TMKDLRGRRCVADIMPTEQYPGLFPIGRLDQDTTGLLLF----STDGNLGNALLhpSHGVSKVYRATIEGSIGQAALEQLAsgILLDDGMTAPARVSVVQAGK------------------------KHSVIELELHEGRKHQVKRMCQAVGHPVV------------------------------------------------------------------------------------
>UniRef50_B8LBG7(230-497:536) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LBG7_THAPS  E=2e-09 s/c=0.24 id=25% cov=68%
----VYVDDDLgfTVLNKPGGIPTHSTISNHAEDVVSMYRasLKEERGDEAHTPH-----VSipirmepemyGLTLASTKKEFCAYITKQLAASKelhdenssngnsipVKKSYRVLVCiKNPDDIDRIEKMVGKTLEHYVDPVSPtpkkfVRNKPKSSnhdwqqclmlITSVGDTKFRAACVSSKYTDSNDFTLahrlwcpdmdhpaedlgvsyvmqLELELLTAKPHQIRGQLAALGCPIVGDTPYGGG----------------------------------------------------------------------------
>UniRef50_A5C4N1(217-328:400) Putative uncharacterized protein n=1 Tax=Vitis vinifera RepID=A5C4N1_VITVI  E=2e-09 s/c=0.58 id=26% cov=39%
------------------------------------------------------------------------------EKKVKKLYRALAA-APMPIGIVTHYM--RPVNIAPRLISEDFIKGWYLCQLEVLECKEVPWPstliEEKYCIEDRGWplknsafkCKINLLTGRTHQIRAQLAACGAPIVGDSMY-------------------------------------------------------------------------------
>UniRef50_C8QZD4(66-203:240) Pseudouridine synthase n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8QZD4_9DELT  E=2e-09 s/c=0.47 id=32% cov=52%
-----------VLLNKPAGYVT--TMADPQGRPIVTSLI-NEPGLRLFPVGRLDLDTEGALLLTNDGElAQNILHP---SRQINRTYHATVKGRPNREAlqQLRRGIMLEGRRTWPARIRELRRNQESTT------------------------LEVIIHEGRKRQVRKMFAAINHPVL------------------------------------------------------------------------------------
>UniRef50_B3GZS7(37-191:232) Pseudouridine synthase n=10 Tax=Pasteurellaceae RepID=B3GZS7_ACTP7   E=3e-09 s/c=0.42 id=28% cov=59%
-----FEDTVVVLFNKPFDVLTQ------FTDEQGRQTLKDFIPiPQIYPVGRLDRDSEGLLLLTNNGEIQHRLANpKFEK---QKTYLAQVEGIPQAA---DLAKLEKGVELKDGLTKPAKAKAISAPNYE----WQTAPKIRERKTIPTSWIELKIHEGKNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_Q8I312(504-561:955) Pseudouridylate synthase, putative n=2 Tax=Plasmodium RepID=Q8I312_PLAF7  E=5e-07 s/c=0.99 id=29% cov=21%
--------------------------------------LKTQDKSYIYTLHRLDKLTSGIVFFGKNKKFSTYFSQNLSDNKIKKTYITRVQG------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6P087(82-341:343) RNA pseudouridylate synthase domain-containing protein 3 n=35 Tax=Theria RepID=RUSD3_HUMAN  E=3e-09 s/c=0.25 id=25% cov=61%
----------LVTLNKPQGLPVTGKPGELTLFSVLPELsqslgLREQELQVVRAS---GKESSGLVLLSSCPQTASRLQKYFTHaRRAQRptaTYCAVTDGIPaASEGKIQAALKLEHIDGVNLTVPVKapsrkdilEGVKKTLSHFRVVAT-----------GSGCALVQLQPLTVFSSQLQVHMVLQLCPVLGDHMY-------------------------------------------------------------------------------
>UniRef50_Q6BNX8(31-326:339) Pseudouridylate synthase PUS5 n=2 Tax=Debaryomyces hansenii RepID=PUS5_DEBHA  E=4e-09 s/c=0.22 id=24% cov=85%
-----------LIINKPSGI---QCNGTKSHSNYLLPQLYKQLKAHFSannpnyklnpdqykVVHRLDKYVSGGLIIArgKNANAFRKsFSNQNTNLSVKRKYIGLVpipntvsfkqhlhefgdlkvqhenevrylnrpesvtdkKGLIFKddsltEGIINFDIVALPKDDRRNKNTGELVTYSALTKFKILhsmSQVPTNEQISRFPklyknKTIYPII-IELETGRKNQIRDHiLQAFKVSLLNDDKFIDFKmvqksnTANINSEVYNSNQIGLHSAYISIsKSSFANEYV---IPIPEG-----DEYLWKGFLDEN-----------------
>UniRef50_A8BNG7(148-425:568) DRAP deaminase n=2 Tax=Giardia intestinalis RepID=A8BNG7_GIALA   E=5e-09 s/c=0.23 id=27% cov=69%
------EGDHVFC-EKPASMPVHPCGKycyHSVNELVASPDTKLTTKKSLRACNRIDKLVSGLIVMAdSSKEAEQKRNEIVERGNV-KVYLAncrmvstdisprrvcLIWGpmglrfkgnytsrciHFNTHTELFGANLERLDKYNEcieqltacshsfgkgvTFMRDKEMLwfQDSDTYSRFVsskkctallqdliavqldptqsmadigehqAAITVIEYVHVDSSTQTALAMCVPITGRTHQLRLHLQAAGTPIHNDPSHGGLQAN-------------------------------------------------------------------------
>UniRef50_Q38VQ0(53-188:239) Pseudouridine synthase n=6 Tax=Lactobacillus RepID=Q38VQ0_LACSS   E=3e-08 s/c=0.45 id=27% cov=52%
--PIRYQTNFYWLLNKPAGVIS--ATTDPQKTVMDLFAPADYR-EDLFPVGRLDKDTTGLLLITNDgDLAHDLLSP---KKHVAKTYRAKIAGVVTAA---------DQAQFAAGLKLRDFDAQPAQLTILRTDTARQE-----------SLIEVEIHEGKFHQ-------------------------------------------------------------------------------------------------
>UniRef50_A5KLG0(67-215:261) Pseudouridine synthase n=8 Tax=Bacteria RepID=A5KLG0_9FIRM   E=3e-08 s/c=0.41 id=27% cov=53%
-------------LNKPAGVV---SATEDKKERTVIDLIKESKRKDLFPAGRLDKDTEGLLLITNDgQLAHRLLSP---KKHVDKIYYAKIKGIVTEE---DVRLFEKGVHIGDEkptmpaaleiLSVQKERRKEKIKEQKILPETKN---ETDEKEDGYSEIYLTIKEGRFHQ-------------------------------------------------------------------------------------------------
>UniRef50_B3L0N6(22-277:392) Putative uncharacterized protein n=3 Tax=Plasmodium RepID=B3L0N6_PLAKH  E=5e-08 s/c=0.24 id=23% cov=77%
---VLYQDDDYLVVNKAYGVSTFGRApqkesiiksleelnLEGHESANVLYKLHNHVG--------------GCLLICKNKF--------IKNHTYGNTFLALVYGQVENAQNVKVKLGlKYLPNSGIMIPSNDQN------HLRDLKSIKYDVISNtiSYETHKFSLLKI------------HTAakdakfikplvfySLYTCIVGDNEYvggwrkliknGFFAYRDVGGQVERANRlllkklphmgknnelmLHLHCLTVTFQSACS-RVVSVSSPLPRHMRETLNFLGAPSLSQTIE----------------
>UniRef50_A3LZQ0(16-206:265) Pseudouridylate synthase (Fragment) n=1 Tax=Pichia stipitis RepID=A3LZQ0_PICST  E=6e-08 s/c=0.32 id=21% cov=64%
-----------VVVNKPSGI--QCSGFKNYAHHLLPQLTKKFKALHPDrtlnasqfkLVHRLDKYVTGGLVVARDRKWAMKSSKSLSSKgnspdSIIRRYVGLLP-IPEDDslksGWITYDIQAPQKDYKGSTETRKVLSYKALTIFQILDELKLQPTKTQlsmypkiYSGKCIVPIILQLQTGRKNQLRDHtLQSFNTTLLNDD---------------------------------------------------------------------------------
>UniRef50_UPI000155BA23(44-120:152) PREDICTED: hypothetical protein, partial n=1 Tax=Ornithorhynchus anatinus RepID=UPI000155BA23  E=1e-07 s/c=0.77 id=29% cov=22%
--------------------------------------------------HQLDFSTSGALCVALNRAAAGRAYRCFKERIVTKAYVALVRGHVGEDRmTINHAIGKN---------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6AV89(87-221:268) Pseudouridine synthase n=17 Tax=Rhizobiaceae RepID=C6AV89_RHILS   E=2e-07 s/c=0.44 id=27% cov=52%
-----------LMLNKPRGLVT--TRHDPEGRPTVYDCLRDFDIPHLSPVGRLDKASEGLLLFTNDTEFAQILLDPVTH--VTKTYH----------VQIDR-IMDDEDIAAMTAGIRHDGELLTATAARRLRQ-----------GDRNSWIEVELDEGRNRQIRRMLEALG----------------------------------------------------------------------------------------
>UniRef50_C5WHE9(66-145:245) Pseudouridine synthase n=3 Tax=Lactobacillales RepID=C5WHE9_STRDG   E=2e-07 s/c=0.73 id=31% cov=31%
------------ILNKPAGFLS--ATKDRAQATVIDLLDETARQKDVFPVGRLDKDTRGLLLLTNNgQLAHDLLSP---KKHVTKEYLAKVAGIMTD--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5KUW6(27-171:182) Ribosomal large subunit pseudouridine synthase B, putative n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5KUW6_9ALVE  E=3e-07 s/c=0.40 id=28% cov=53%
---------------KPRGM---------ETTCTAGSGLRKFLDRgRLHPVGRLDRDTTGLLLLSSDGDcTNRILHS-----TINKTYAALVRGVLPEglmkkvvSEGVDLPDGHVDVTRLETINDGDTVP------FGLVA-----YPLSSIPTNGCSMVRITTTCGRNRVVRRTLCALGHPVL------------------------------------------------------------------------------------
>UniRef50_A3CPQ5(64-188:242) Pseudouridine synthase n=3 Tax=Firmicutes RepID=A3CPQ5_STRSV   E=7e-07 s/c=0.46 id=29% cov=48%
-------------LNKPRGVIS--SVSDDKGRKTVVELL-PQVKERIYPVGRLDWDTSGILILTNDGD---FTDEMIHPRnEIDKVYVARVKGLANKE--VLRPLTRGIEIEGRKT-------KPAV--YEIIKV---------DPAKNRSVVQLTIHEGRNHQ-------------------------------------------------------------------------------------------------
>UniRef50_C0W3E8(133-287:325) Pseudouridine synthase n=1 Tax=Actinomyces urogenitalis DSM 15434 RepID=C0W3E8_9ACTO  E=1e-06 s/c=0.36 id=30% cov=55%
-------DPDVITVllHKPAGVVT--TMEDPQGRPTVADLAEQFISEHrtelehpesVRLVHvgRLDTETEGLLLLSNDgDLAHRLMHPSF---EISKTYVAIVEGQVE---------GWVPRKLRRGIELDDG-----------LAQADRVVVKDAGPSG--SIVEITLHSGKNRIVRRMLDAVGHPV-------------------------------------------------------------------------------------
>UniRef50_A4J3M3(69-200:309) Pseudouridine synthase n=167 Tax=Bacteria RepID=A4J3M3_DESRM   E=1e-06 s/c=0.43 id=31% cov=50%
--------------NKPRGYVT--TLSDERDRKTVVDLLK-GVEQRVYPVGRLDYDSEGLLLLTNDGE----LTQALTHpkHKVKKTYLAKVDGIPETE---------ELKAMAKGLVLEDGPTAPA--DVRLAGTGDNR-----------ALLEISIHEGRNRQVRRMCEHIGY---------------------------------------------------------------------------------------
>UniRef50_P72581(42-191:261) Uncharacterized RNA pseudouridine synthase slr0612 n=16 Tax=Bacteria RepID=Y612_SYNY3  E=1e-06 s/c=0.37 id=27% cov=55%
-----------IVFYKPYGVLCQ----FTDNSAHPRPTLKDYINlPDLYPVGRLDQDSEGLLLLTSNGKLQHRLaHREFAH---QRTYFAQVEGSPTDE---------DLEPLRRGITFADYPTRPAI-----AKIITEPDFPPRNPPIRYrasiptSWLSITLTEGRNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_Q04F57(49-204:237) Pseudouridine synthase n=2 Tax=Oenococcus oeni RepID=Q04F57_OENOB   E=1e-06 s/c=0.36 id=29% cov=55%
--DIVYVDnkkineesfEYYL-LNKPAGYVS--SNRSYPNQPSVIELIK--TKTRIFSVGRLDQDTTGVLLLTNDGELTQKLTH--PKHRIKRTYAAWVKGIVNEDEIeqLTKPIRFDGEiyfPQAARILKVDQKRQE-------------------------SLIEITIAEGKNHEIKKILDFIGHPVI------------------------------------------------------------------------------------
>UniRef50_A9KNY1(72-150:240) Pseudouridine synthase n=3 Tax=Firmicutes RepID=A9KNY1_CLOPH   E=1e-06 s/c=0.71 id=29% cov=27%
-------------LNKPAGVVS--ASNDKKQTTVV-DLIDEAKRKDLFPVGRLDKDTEGLLIITNDgDLAHQLLSP---KKHVDKVYFA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q042N1(66-203:245) Pseudouridine synthase n=3 Tax=Lactobacillus gasseri RepID=Q042N1_LACGA  E=2e-06 s/c=0.40 id=23% cov=53%
---IAYQQYHYFLLNKPKGVIS-ATEDRSQQTVISLLKTKDRY-QGIAPVGRLDKDTTGLLLLT-NDGALA--HELLApNKHVAKVYRAKIAGVPDPET---------AKKFAQGLILGDGTKlKPA-----------KLKILKQDQDNNLSQIEIQIQEGKYHQI------------------------------------------------------------------------------------------------
>UniRef50_A6LIA0(321-390:495) Pseudouridine synthase n=23 Tax=Bacteroidales RepID=A6LIA0_PARD8   E=2e-06 s/c=0.80 id=29% cov=27%
-----------IVLNKPKNCVT--TSDDPQERLTVMDLVKNACQERIYPVGRLDRNTTGVLLLTNDGDLASKLtHPSFKKKKI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2K4S3(132-266:312) Pseudouridine synthase n=10 Tax=Rhizobiaceae RepID=Q2K4S3_RHIEC   E=2e-06 s/c=0.41 id=24% cov=52%
-----------LMLNKPRGLVT--TRQDPEGRPTVYDCLKNFDIPHLSPVGRLDKASEGLLLFTNDTEFAQTLLDPLTH--VTKTYH----------VQIDRLMDDEEIAAMTSGIRHDG------------ELLTAAATRRLRQGDRNSWIEVELDEGRNRQIRRMLEALG----------------------------------------------------------------------------------------
>UniRef50_O05668(79-218:256) Uncharacterized RNA pseudouridine synthase ML1370 n=49 Tax=Actinomycetales RepID=Y1370_MYCLE  E=2e-06 s/c=0.39 id=28% cov=54%
-----------LALNKPRGMYSTMSDDRGRPCVGDLIERRVRGNKKLFHVGRLDADTEGLILLTNDGElAHRLMHP---SHEVSKTYLATVKGAVPR------GLGKKLS-----VGLELDDGPAHVDDFAVVDAI-----------PGKTLVRLTLHEGRKRIVRRLLTAAGFPV-------------------------------------------------------------------------------------
>UniRef50_B8ET33(75-214:255) Pseudouridine synthase n=29 Tax=Proteobacteria RepID=B8ET33_METSB   E=3e-06 s/c=0.39 id=31% cov=53%
----------VIALNKPRGVTCSRKEAGPLVFDLLPPRFR-LREPALSTVGRLDKDTSGLLLIT-DDGAL--LHRLISpKHNIAKRYCAkLARPLRGDEAEI-------FASGEMMLDDEAKPLLPAV--LRVLSPTEAEVSVTE---------------GRYHQIRRMFAATGNHVL------------------------------------------------------------------------------------
>UniRef50_A4J9G8(69-194:249) Pseudouridine synthase n=47 Tax=Bacteria RepID=A4J9G8_DESRM   E=5e-06 s/c=0.43 id=32% cov=32%
-----------LMLNKPQDVLS--ATEDASDKVVIDLLDPTYHSFNPFPVGRLDKDTEGLLLLTNNgKLAHQLLSP---KKHVPKTYYALVQGLVTEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0JV58(225-386:406) Pseudouridine synthase n=37 Tax=Actinobacteridae RepID=A0JV58_ARTS2   E=9e-06 s/c=0.33 id=26% cov=55%
-------DENMVymVFNKPKGVVS--TMEDPDGRPCISDFVRNTHGERLFHVGRLDVATEGLLLLTNDGELANRLTH--PSYEVPKTYLVQVRGPFPQ-----------GIGAQLKAGVELEDGMASVDSFKLVDS-----------TPGHVLIEVVLHSGKNRIVRRLFDAVGFPVL------------------------------------------------------------------------------------
>UniRef50_C0FY58(91-211:261) Pseudouridine synthase n=3 Tax=Clostridiales RepID=C0FY58_9FIRM   E=9e-06 s/c=0.44 id=31% cov=30%
---------------KPAGCVT--ATEDQLHKTV-MDYLTDTVRSDLFPVGRLDIDTEGLLLITNDgALAHDLLSPA---KHVEKTYYAVIDGVVTEK-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q11WC7(32-175:224) Pseudouridine synthase n=2 Tax=Sphingobacteriales RepID=Q11WC7_CYTH3  E=1e-05 s/c=0.37 id=18% cov=56%
------------IINKPFNMVSQ---FISSDAVNLLGNLDFTFPEGTHAVGRLDNESEGLLILTTNKKVTRLLFQGTKKHT--RTYLVLVKNKVSEETLKQLQTGISIRVKGGGNYISSPCEASIVTDAKAIYSY----AADTRENYPHTWLLLTLTEGKFHQVR-----------------------------------------------------------------------------------------------
>UniRef50_A8SYF2(65-145:239) Pseudouridine synthase n=1 Tax=Coprococcus eutactus ATCC 27759 RepID=A8SYF2_9FIRM  E=1e-05 s/c=0.65 id=27% cov=31%
-------------LNKPAGCV---SATKDNVHQTVIDLLNGENTKDLFPVGRLDLDTEGLLIITNDgRLAHHLLSPA---HHIAKTYYADIDGYVDDQTI-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4FUC8(61-143:243) Pseudouridine synthase n=1 Tax=Catonella morbi ATCC 51271 RepID=C4FUC8_9FIRM  E=1e-05 s/c=0.63 id=30% cov=30%
---------HYYLLNKPEGILS--ATEDRHHQTVIDWLGEGYQHLDLFPVGRLDIDTTGLLLLTNNgQLAHQLLSP---KKKVDKTYTATIRG------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7VSS7(71-151:256) Pseudouridine synthase n=2 Tax=Clostridiales RepID=A7VSS7_9CLOT   E=1e-05 s/c=0.65 id=35% cov=28%
--------------NKPAGVVS--ASRDSREKTVVDLVPPVLSRRDLFPAGRLDRDTTGLLILTDDgELAHRMLSP---KKHVYKLYEASVDG------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q11YT0(390-478:562) Pseudouridine synthase n=9 Tax=Bacteroidetes RepID=Q11YT0_CYTH3   E=1e-05 s/c=0.59 id=29% cov=28%
-----------VLLNKPKDFIT--TMEDENDRKTVMQLVANATKERIYPVGRLDRNTTGLLLFTNDGELAQKLTH--PSNKVKKIY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0D9T3(103-282:300) Pseudouridine synthase n=1 Tax=Clostridium asparagiforme DSM 15981 RepID=C0D9T3_9CLOT  E=2e-05 s/c=0.29 id=32% cov=60%
----------LLAVNKPKGVVCTASDKDKAPNIVDMI----QYPVRVYYVGRLDKDSEGLVLMTnqgdlvnkimRSGNAH------------EKEYQVVV----------DRPVTAEFLARMEKGVRLKE-----------LDRTTLPCKVRKTGDKRFSIV---LTQGlnR--QIRRMCEACGCHVrslkrvrvmnicLGDLKSGEYRQ-VEGAEYREFMKLLEHSTNLSFR---------------------------------------------------
>UniRef50_C5EVC9(101-235:294) Pseudouridine synthase n=6 Tax=Clostridiales RepID=C5EVC9_9FIRM   E=2e-05 s/c=0.39 id=32% cov=48%
----------LLVVNKPRGIVCTTSDKDRAMNIVEYLDY----PERIYPVGRLDKDSEGLLLMTnqgdlvnkimRSGNAH------------EKEY--IV--------TVDRPL---TDDAMDRMAKGI--------YLRELETVTRPCKVKRVDGKTFSII---LTQGlnR--QIRRMCEACGCHV-------------------------------------------------------------------------------------
>UniRef50_B2RK43(249-334:439) Pseudouridine synthase n=1 Tax=Porphyromonas gingivalis ATCC 33277 RepID=B2RK43_PORG3  E=2e-05 s/c=0.60 id=30% cov=30%
--EVIYKDKRVeieskvyVLLNKPKNCVT--TSDDPECRTTVMDIVRYACPERIYPVGRLDRNTTGVLLITNDGDLASKLtHPSFKKKKI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0S1L0(58-199:242) Pseudouridine synthase n=2 Tax=Finegoldia magna RepID=B0S1L0_FINM2   E=2e-05 s/c=0.37 id=23% cov=55%
------EDKIYIAINKPIGYAS--TVKDKFADKKVVDLIKS--DTRVYPVGRLDKDSHGLLILTNDgEFTYELTHPKFEHK---KIYEVLVKGKPNKTEIKQLKDGILLDGYKLKKSK--------------IEFIENVKNDTKY--------RVTIFEGRNRQIRRMFDFINHPVL------------------------------------------------------------------------------------
>UniRef50_A2RP35(151-281:328) Pseudouridine synthase n=172 Tax=Firmicutes RepID=A2RP35_LACLM   E=2e-05 s/c=0.39 id=28% cov=31%
-------------LNKPQGVVS--ATKDNVFKTVVQLLSEKDFRKDIFPVGRLDKNTEGLLILT-NDGALGHDLTQPKKH-VEKEYFARIDGKVTDE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0Z1Z6(25-208:208) Pseudouridylate synthase n=2 Tax=Proteobacteria RepID=A0Z1Z6_9GAMM   E=3e-05 s/c=0.28 id=25% cov=56%
---------DIILLNKPFRVLSQFSDRDNDPPRLTLANL--LSAPEFRVAGRLDYDSEGLTLL--TDD--GKLQQQIANPKFKvwKTYWVQVEGAPKQQAI---------EQLTSGVVLNDGLTKPAK-----VRAIDPPDLWERSPSVRFrahipdAWLEISIQEGRNRQIRRMTAAVNLP--------------------------------------------------------------------------------------
>UniRef50_Q1D5Q2(69-204:745) Pseudouridine synthase n=6 Tax=Bacteria RepID=Q1D5Q2_MYXXD   E=3e-05 s/c=0.38 id=26% cov=52%
-------------LYKPVGVVT--TLSDPQGRPTVANYV-EETGKRLFPVGRLDYDAEGALLFTDDgALAHKLTHPSFQ---VPRTYLAKVKG---------APDTATLDKLRGGVRLEDGMATP-------------VSVSVFEAAERNTWLKIVVAEGRPHLIKRLCAAVGHPVV------------------------------------------------------------------------------------
>UniRef50_A8U4V7(65-163:239) Pseudouridine synthase n=10 Tax=Lactobacillales RepID=A8U4V7_9LACT   E=4e-05 s/c=0.52 id=23% cov=27%
-------------LHKPAGVVS--AVSDAVNQTVIDLIEPSQRVPGLFPVGRLDKDTEGLLLL--TNNGQLGYQLLIPKKEVTKCY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1F236(89-197:406) Pseudouridine synthase n=8 Tax=Bacteria RepID=C1F236_ACIC5   E=4e-05 s/c=0.47 id=22% cov=39%
-------------LNKPKGYVTTVSDPEGRHTVMEFFHGRGKGGERLYPVGRLDYASEGLLLMTNDGALANTLTK--ASSHVEKVYLVKVSGRPTEEQleQIRAGIMIDRGRPGEGRV------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1GHH2(4-157:221) Pseudouridine synthase n=12 Tax=Bacteria RepID=Q1GHH2_SILST   E=4e-05 s/c=0.33 id=25% cov=59%
----------LIRFNKPFDVL--PQFTDRGSEGSPRATLSDYVDcPGVYPAGRLDRDSEGLMLLTDNGRLQAWISD--PKHKLEKTYWVQVEGIPTEDALKALRQGVDLKDGMTRPAKAELISEPAQ-----LWARTPPIRERKSVPT--AWLELKISEGKNRQVRRMTAAMGYP--------------------------------------------------------------------------------------
>UniRef50_C7M7R0(213-289:387) Pseudouridine synthase n=4 Tax=Bacteroidetes RepID=C7M7R0_CAPOD   E=5e-05 s/c=0.66 id=31% cov=30%
--------EYIL-LNKPKGFIT--TTNDEKGRKTVMDLVANATNVRILPVGRLDRATTGLLLLTNDGELTKKLTH--PTHGVRKIYHVI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q65HX7(65-199:244) Pseudouridine synthase n=5 Tax=Firmicutes RepID=Q65HX7_BACLD   E=5e-05 s/c=0.38 id=29% cov=42%
--------------------------------------------ERIYPIGRLDYDTSGLLLLTNDGDFANKL--MHPKYEINKTYVAKLKGI---------PLKENLKKLERGVRLEDGKTAPAKVKLLSLDKKKQT-----------SIVQITIHEGRNRQVRRMFEAIGH---------------------------------------------------------------------------------------
>UniRef50_Q9F855(66-214:241) Ribosomal large subunit pseudouridine synthase E n=107 Tax=Bacteria RepID=RLUE_VIBCH  E=5e-05 s/c=0.34 id=24% cov=57%
----------VILFNKPYDTLSQFTDGDGRKTLADYIPIKD-----VYAAGRLDRDSEGLLILTNDGILQARLTQ--PQSKAPKTYWVQVEGSPQES---------DLEALRHGVTLKDGPTLPAKVDIMPEPTLWPRNPPVRFRAAiPTTWLAITLMEGRNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_Q15Q67(70-211:241) Pseudouridine synthase n=2 Tax=Bacteria RepID=Q15Q67_PSEA6   E=9e-05 s/c=0.35 id=20% cov=22%
--------DGILVmLNKPLGYVCSHDNNEGMRIYDLLPERWEFRNPKIVSVGRLDKDTSGLILV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9LMF3(81-235:277) Ribosomal small subunit pseudouridine synthase A n=1 Tax=Dialister invisus DSM 15470 RepID=C9LMF3_9FIRM  E=9e-05 s/c=0.32 id=24% cov=56%
-------------LNKPAGVIT--ATEDRYQKTV-LDFFGERRRKDLSPVGRLDKDTVGLLLVTNDGGFHHRL--LSPKKHIDKEYYARIDGRVDEA---------DREKFEKGIYVDEIftalPAKLMIDGYRenALESDFMDLANSRAPKSalenGVSEIRVVVQEGKFHQIKRMFHALG----------------------------------------------------------------------------------------
>UniRef50_B2T6J8(2-152:189) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=B2T6J8_BURPP   E=0.0001 s/c=0.33 id=30% cov=55%
---------HLLALNKPFGTICQFSPHETRASLADWVKVPD-----VYPAGRLDSDSEGLLLL--TDD--GALQARIAEprHKLVKRYWAQVEGA------VDAA---TLKKLARGVDLGDYVTRPCRAEY----VEPTDALWTRTPPIRFraaiptTWIELSITEGKNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_C9KIR7(68-208:250) Pseudouridine synthase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KIR7_9FIRM  E=0.0001 s/c=0.35 id=29% cov=54%
-----------LLLNKPKGYLS--TAKDDRGRRTVLDLL-PEVRERVYPVGRLDNNTEGLLLIT-NDGALmnGLLHPRF---EVEKTYHAGVTGKLTEE---------KLQMLRDGLLLEDGMTAPA-------KVSLLPEREPGERVRGLTRAAITIHEGRNRQVRRMFAAVGC---------------------------------------------------------------------------------------
>UniRef50_B6WWG1(104-274:347) Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC 29098 RepID=B6WWG1_9DELT  E=0.0001 s/c=0.29 id=23% cov=58%
---------------KPAGWhsVSLAGGGGRSLEAAIPSLWAEGAVPPAWaLLQRLDARTSGIVCaaVAEDEDSLAATVRDFRQAEAGgrccKGYLALLSGSLEREACVRRALDMAQRRVVRVLDSEAADAAR-WTWFRPLyhWQGEACHAFARELCRRFSlsvpslpdsltLAGCTIHRGARHQIR-----------------------------------------------------------------------------------------------
>UniRef50_D0IWI1(43-192:223) Pseudouridine synthase n=2 Tax=Comamonas testosteroni RepID=D0IWI1_COMTE  E=0.0001 s/c=0.33 id=30% cov=55%
----------LLCFHKPYGVLSQFTPEGK------WQGLKDWIDvPGVYVAGRLDADSEGLLLLTNDGQLQARIAD--PRHKMEKTYWVQVEGIPDEAA---------LQRLREGVELSDGKTLPA--KARLIE--PQPLMWPRNPPIRVrqnipdCWIELIIREGRNRQVRRMTAAVGHP--------------------------------------------------------------------------------------
>UniRef50_Q2S2G3(70-211:249) Pseudouridine synthase n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S2G3_SALRD  E=0.0002 s/c=0.34 id=27% cov=55%
--------EYLL-LNKPKDTISTTDDPKDRRTVLDAIGVPEDNPSGLFPVGRLDRNTTGVLLVSNDgDLAHRLMHP---RYEIPKIYYVRVQDDVKPHQL-----------DQLKRGVELSDGAAA------------ADQVAYLDPQRKTDIALELHEGRNRQIRRMMEALGHTIV------------------------------------------------------------------------------------
>UniRef50_C4Z9Y4(77-207:250) Pseudouridine synthase n=16 Tax=Bacteria RepID=C4Z9Y4_EUBR3   E=0.0002 s/c=0.37 id=30% cov=27%
--------------NKPSG-CVSATCDNVHDT--VMDYITDAVHDDLFPVGRLDIDTEGLLLIT-NDGALS--HELLSpSKHVAKTYYA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C2MA52(267-393:472) Pseudouridine synthase n=1 Tax=Porphyromonas uenonis 60-3 RepID=C2MA52_9PORP  E=0.0002 s/c=0.39 id=31% cov=27%
-----------VLLNKPKNCVT--TLTDPEGRRTVMDLVHNACTERIYPIGRLDRNTTGILLLTNDgDLAVRLMHPAFRKK---KIY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6XLQ6(75-210:247) Pseudouridine synthase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XLQ6_HIRBI  E=0.0002 s/c=0.36 id=31% cov=49%
-------------LNKPAG--VTCSRKDSGTLITELFPSRwDKRDPLLSPIGRLDKETSGLLLL--TDD------GQLNHRvsspktQTPKRYHVI--------------LDRDLNGDEDSIFAAGELMLESET--KPLLPAELSALGKREAI-------LTLHEGRYHQVRRMFAAVG----------------------------------------------------------------------------------------
>UniRef50_Q6AKZ6(34-259:544) Putative uncharacterized protein n=1 Tax=Desulfotalea psychrophila RepID=Q6AKZ6_DESPS  E=0.0002 s/c=0.21 id=26% cov=74%
--PIIYKDAQLLVVDKPTGFSSQAmTEGEVGITEWLALHLQYQIDLYSSL-------TkscSGVLLLRRKNQIEKAENDQpvkIAEKKYHfisaKRY----RGQTEEDGSW---LVERDNSITEESVR-----------FRFLEE-----------GRDYSLYEaatlscCR---------RVQefAEESGIAIVGD------------GADSPFARLFLHCHSIRLA--ESGH--EFISSTPDSFSFVLKQrdkvlidtaiawerrLGWLQLITNSYRLIQRGELDLP-----
>UniRef50_A9NGL0(65-213:238) rRNA pseudouridylate synthase n=1 Tax=Acholeplasma laidlawii PG-8A RepID=A9NGL0_ACHLI  E=0.0003 s/c=0.32 id=29% cov=32%
-------------LNKPTGYLSTTADIHKRRNILDLILKEDQ-NVRLFPIHKLEYDTSGLLLVTNDGELTKKLTSQ--SESIQKEYVIRTKGIMIKERI-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7GZ55(63-140:250) Pseudouridine synthase n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7GZ55_9FIRM  E=0.0003 s/c=0.62 id=32% cov=30%
-----------IAMNKPCGYVC--TVSDELGRRTVYDLLTD-IDERLFTIGRLDKDSEGLILLTNDgDLAQKLLSP---KRKIEKNYEVVVRGVP----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C2KPR0(95-240:278) Pseudouridine synthase n=3 Tax=Mobiluncus RepID=C2KPR0_9ACTO   E=0.0003 s/c=0.33 id=26% cov=53%
------------AFNKPVGTV---STMQPEDDRPCLGDWATKLPQRVFHVGRLDVATAGLILLTNNGDLANRLVH--PRYEVPKTYVAMVQGQVKP--------------GLGKVLRRGVELEDGVTKVDTFKLVEVRRGS--------SIVQLTLHSGKNRVVRRLLSEVGHPV-------------------------------------------------------------------------------------
>UniRef50_Q6SI36(68-210:255) Pseudouridine synthase n=1 Tax=uncultured marine bacterium 105 RepID=Q6SI36_9BACT  E=0.0003 s/c=0.33 id=19% cov=55%
---------YLLVC-KPRGYVT--TRFDPEGRRTILNLISN-VREYVYPVGRLDYDSEGLVILTNDGTLAARLTH--PRYGVERVYEVRVRGVPSQAAI-----------DSLRHGVLINGRRTASSSVKFLRRL-------KAKSSENALLRVAIREGRNRQVRKMCEAIGHPVI------------------------------------------------------------------------------------
>UniRef50_A5Z4I7(2-70:175) Pseudouridine synthase n=1 Tax=Eubacterium ventriosum ATCC 27560 RepID=A5Z4I7_9FIRM  E=0.0004 s/c=0.69 id=29% cov=27%
-------------LNKPAGVL---SAVSDNNCKTVIDLLDVTPKKGLFPVGRLDKDTEGLLLITNDGElSHNLLSPA---KHVDKTYY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8NZC3(70-207:246) Pseudouridine synthase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8NZC3_ERYRH  E=0.0005 s/c=0.34 id=28% cov=52%
------------ILNKPRGIVS--SANDDKDRESVVDLVPNDI--RVFPVGRLDRETTGALILTNDgDFAYYMTHPKF---DLSKIYRVSVRGRLSYE--------------------VTNSLKEGITiegvEYKGVEISRVKYDAAK-DKTQFS---ITLHEGKNRQIRKIFAHFGLPVL------------------------------------------------------------------------------------
>UniRef50_Q3MC44(93-233:288) Pseudouridine synthase n=21 Tax=Cyanobacteria RepID=Q3MC44_ANAVT   E=0.0006 s/c=0.33 id=25% cov=54%
-----------LLLNKPTGVVS--TCYDPQGRKTVLDLLPEELrkGSGLHPVGRLDAYSTGALILTNDGDLTFKLTH--PSHNIPKTYQILVKGHPPEA--------------VLKMWREGVLLDGRKTRKAKVSLLESLAEKSR--------LEIVLQEGRNRQIRRVAEQLGYPVI------------------------------------------------------------------------------------
>UniRef50_A5EVQ2(77-155:266) Pseudouridine synthase n=1 Tax=Dichelobacter nodosus VCS1703A RepID=A5EVQ2_DICNV  E=0.0008 s/c=0.59 id=32% cov=30%
--------------HKPAGEIC--TRKDPEGRVSVFQHLPKISHGRWVAIGRLDLNTSGLLLFT-NDGA---LANQLMhpSAEIEREYWVRVAGEVTEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8ZPZ1(41-190:221) Ribosomal large subunit pseudouridine synthase E n=30 Tax=Enterobacteriaceae RepID=RLUE_SALTY  E=0.0009 s/c=0.31 id=25% cov=58%
----------VVLFNKPYDVLPQ------FTDEAGRRTLKDFIPvQGVYAAGRLDRDSEGLLVLTNDGALQARLTQ--PGKRTGKIYYVQVEGIPD-----NAALQALRTGVTLNDGPTLPAGIEIVAEPDWLWPRTPPIRERKNIPT--SWLKVTLYEGRNRQVRRMTAHVGHP--------------------------------------------------------------------------------------
>UniRef50_C6Y027(299-370:472) Pseudouridine synthase n=1 Tax=Pedobacter heparinus DSM 2366 RepID=C6Y027_PEDHD  E=0.001 s/c=0.65 id=32% cov=24%
-----------VLLNKPKDYIT--TTDDPQERRTVMQLVEKASRERIYPVGRLDRNTTGLLLMTNDGDLADKLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2UL66(77-320:323) Pseudouridine synthase n=2 Tax=Verrucomicrobiaceae RepID=B2UL66_AKKM8  E=1e-65 s/c=1.03 id=31% cov=90%
-LDILYEDEDVVVINKESGMVVHPAAGNPDGTIVNALLHHCgdlsgiGGVERPGIVHRLDKDTSGCLVIAKNDGAHQSLTAQFAARSTEKRYLAVVQGIPSQsSGTVFTHIGRHPVNRLKMAVVNPGSGKAAITDYDLL---------CADPSTDSSLVLCTLHTGRTHQIRVHMLYLGHPLIGDPIY-----AKPARQKAKPGRLMLHAWRLGFDHPRTGKRMDFEAPVPPEYTPWLQLFpnGLYGAIPELRPVQ-------------
>UniRef50_A9BFW4(85-311:319) Pseudouridine synthase n=8 Tax=Thermotogaceae RepID=A9BFW4_PETMO   E=2e-62 s/c=1.06 id=33% cov=83%
-LNILYEDEELIVINKPAGLIVHPTPSIKTGTLVNALMHHvkdldktMQDPNRLGIVHRLDKETSGVLVVAKNAFSHHLLSKEFKERKTMKYYLAIVEGTLKeKEGEINLPLGRHPILRHKRAVV--YNGKEAITEYKTLKEF----------GDLATLVWIRLRTGRTHQIRVHFKYIGNPLIGDSLYGKNKIEKNLQIPVG--RQMLHALKLGFYHPKTKEWMEFLAPLPDDFKNLL-----------------------------
>UniRef50_B8FT16(107-327:334) Pseudouridine synthase n=70 Tax=Bacteria RepID=B8FT16_DESHD   E=4e-62 s/c=1.09 id=33% cov=83%
-LEILYEDEDVLVVNKSQGMVVHPAPGAWTKTLVNALLYHCRnlsginGVLRPGIVHRIDKDTSGLLVVAKNDLAHQGLAEQIKAHSMARRYLAIVHGvVFEPSGTVEAPIGRDPAD-RKKMAVVFQNAKEAVTHYEVLERFR-----------DFTLLEARLETGRTHQIRVHMAYLKHPVLGDPLYGPRK------NPFGLQGQMLHAQLLGFQHPRSGEYMEFSAPASGMFQKVLEE---------------------------
>UniRef50_C1F7V3(104-353:355) Pseudouridine synthase n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F7V3_ACIC5  E=1e-60 s/c=0.94 id=32% cov=87%
-LDIIYEDKDLIVVNKPAGMMVHAGSGATDsarnrGTLVNALLGRQeklsktGGDLRPGIVHRLDKETSGLIIVARNDAAHQRLAEMFSQREIHKTYLALVHGHIAEDrGTINAAIARDVIRRTRMTTRRTEGARTAISHYRVQRRIETRW-------GKFTLVSVRIETGRTHQIRVHLSSIGHPVVGDTHYGapttivlpvanrARRKQLPAPEGLSLPRNFLHAAELKFPHPRSEKPLHLEAPLPAELVAFLEQL--------------------------
>UniRef50_P65834(84-310:326) Ribosomal large subunit pseudouridine synthase D n=321 Tax=Gammaproteobacteria RepID=RLUD_ECOL6  E=6e-60 s/c=1.03 id=28% cov=84%
-LDIVYEDEDIIVINKPRDLVVHPGAGNPDGTVLNALLHYYPPiadVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAV--HPMGKPAVTHYRIMEHFRV-----------HTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEafistlRKFDRQALHATMLRLYHPISGIEMEWHAPIPQDMVELIE----------------------------
>UniRef50_Q8K9E9(84-310:315) Ribosomal large subunit pseudouridine synthase D n=4 Tax=Buchnera aphidicola RepID=RLUD_BUCAP  E=2e-59 s/c=1.02 id=27% cov=84%
-LNTIYEDSNILIINKPPGLVVHPGAGNQDGTILNALLYRYtniSSIPRCGIIHRLDKDTSGLMVIAKTIFSYNKLVTLLKKRKIIRKYQGIIKGNMISGGIVNYPIMRHPFKRI--CMTTDSLGKKSITHYKIINRFKF-----------HTHVSFRLETGRTHQIRVHMLHIGYPLLGDPLYGGidygcnyFQENRNIYRKFNLFRQALHADYIEFIHPFTQKVMSWSASLPQDMKDIL-----------------------------
>UniRef50_A0Q1S9(83-299:301) Pseudouridine synthase n=32 Tax=Clostridium RepID=A0Q1S9_CLONN   E=2e-59 s/c=1.06 id=32% cov=82%
-LDVIYEDKDIVVINKPKGIVVHPTKRHQNGTLsngVLYYFKEKNENSIVRLVNRLDMDTSGLVLIAKNAYSHMALSRDMQKDDFVKSYLAIVHGNLKEKsGVINKPIYRVGEGTLRR--VIDERGQRSVTRFKVVESYEDAD-----------LVELTLETGRTHQIRVHLSSIGHPIYGDSLYGK-------EEHEYIDRQALHAYKLQIPHPKDGRILKLESDLPDDMKNLISKL--------------------------
>UniRef50_Q4FN11(82-321:326) Pseudouridine synthase n=4 Tax=Bacteria RepID=Q4FN11_PELUB   E=1e-58 s/c=0.95 id=28% cov=86%
-LQIVYEDDDLLIINKPAGIIMHPGAGNYDETIVNALMHYNKDSlstigdeLRPGIVHRIDKDTSGLIVIAKNNETHENLSHQFSEHTITRVYQLLIWGKLrPSSGKIDTFITRSSKNRQMMEVSNSK-GKRAITNYKTIEIFEND------KTPTLSLVECRLETGRTHQIRVHMTHMGNSIMGDGKYKKKYKKLKNIDTnlenliYKLDRQFLHAQTLGFIHPRTNEEMVFTSILPQELENIL-----------------------------
>UniRef50_C1FEQ4(103-354:357) Predicted protein n=2 Tax=Micromonas RepID=C1FEQ4_9CHLO   E=2e-58 s/c=0.90 id=28% cov=87%
-LDVVFEDDHLVVVNKPPGMVVHPSAGHAGGSLVNALLFHCNERsnrgddaskmidvPRLGVVHRIDKGTSGLLVMAKDAAAQAGLQTQFANRSVRRRYLAIVLGTPAREsGRIDAPIGRDPADRLKMAIVRGATGRQAISNFGV---------RARLVRGNASLVEWQLETGRTHQIRVHAREMGHPIVGDeayggggsaaaeflRRDGAMSAAAAREIVAKCARPMLHARSLGFRHPVTGEEISFAVEPPPDFVDAFTEL--------------------------
>UniRef50_Q7UHX8(79-324:334) Pseudouridine synthase n=1 Tax=Rhodopirellula baltica RepID=Q7UHX8_RHOBA  E=5e-58 s/c=0.92 id=32% cov=84%
-LDILYEDDGLVVINKPAGMVVHPARGNWTGTLTSALAFRFQslsdvgGPTRPGIVHRLDRDTSGVIVVAKNNAVHLNLAAQWHDRLVQKEYTAITFGRLDRDRDWIHAsIGRHPYQRDKQAIREgHATSKTASTFYEVVER-----------HGRVTRVDVRPKTGRTHQIRVHLAHIGCPILCDRLYGGHSElsrsqirrlagtevatpgvkPTPEGEEILLSRQALHAKALTFTNPQTGKEMTLTAPLPPDLQAV------------------------------
>UniRef50_A3RGY8(110-342:353) Pseudouridine synthase n=1 Tax=uncultured bacterium RepID=A3RGY8_9BACT  E=6e-58 s/c=0.97 id=25% cov=88%
-LEVIFEDDAILVLNKPPKLVVHPAAGHWSGTLLNGLLAYAPtliDVPRAGIVHRLDADTSGLMVVAKTLAAQTDLVRQLQSRTVTREYWALVLGVPSQRGVIDAAIGRDPRNPLRFKVSTTEAAKPARTHYATLDSTK-------NAGADISWLACRLETGRTHQIRVHLEHVGHPLIGDPVYRRRLPPRgePAARWKEFDRQALHACRLALDHPVSRQRLNwFHSP-AADLAQLMHELGF------------------------
>UniRef50_D1CBT6(91-307:313) Pseudouridine synthase n=1 Tax=Thermobaculum terrenum ATCC BAA-798 RepID=D1CBT6_THET1  E=9e-58 s/c=1.04 id=32% cov=82%
-LRVVYEDDKIIVIDKPAGMVVHPSPGHYDNTLVNALIARypdllKQPTDRPGIVHRLDKDTSGLIIVARDLDTLNYLQGQMKARKIFKEYTLLCCGALdPPEGRIEAPIGRDLRDRTKMSVI--AGGKEAVTEYSTIQSL-----------GKYTLAIARPITGRTHQIRVHFAAIGHPIAGDPIYGNCRLE-------GLNRQFLHASRLGVVMP-NGEYKEWHSPLPEDLRQSLEK---------------------------
>UniRef50_C2D7A7(86-323:338) Pseudouridine synthase n=1 Tax=Atopobium vaginae DSM 15829 RepID=C2D7A7_9ACTN  E=2e-57 s/c=0.94 id=25% cov=87%
-LDIRYEDDYLLVISKQTGLVCHPSPGHVDDTLSNALVAHCgyehlgllQGDDRPGIVHRLDMDTTGLMVAAKDNTTQQALQDLIRLRVFDRRYIVLVQGYVtPDEGTITTGIARSKKNRLKMCISKDPASREAITTFKTLERFE-----AGSKDDGYSLLECHLYTGRTHQIRVHMRYVGHSVVGDPLYGR----KGDALNQGLQRQFLHSWRMSFDHPITHEHLQFCDKLPSDLSEVLARL--------------------------
>UniRef50_Q1N5G6(9-235:236) Pseudouridine synthase n=1 Tax=Bermanella marisrubri RepID=Q1N5G6_9GAMM  E=8e-57 s/c=0.98 id=48% cov=88%
---ILYQDDDLIAINKPSGLLVHKSWVAKDAKEFALQIVRDMSGKHVFPVHRLDRPTSGVLLFGFSGEIAQQVQAQWE--QANKTYWAVVRGWLKEQTLVDHALKGMADYGQDVEIV-----QEAQTHFKPIDYVEIDAEIDRYPKSRFSWVEAKPKQGRTHQIRRHLKHLSHPIIGDARYGKGKYNRYITEHYDCPRLLLHHQQLEMTHPVSGSKLMITAPLEGAMQSLFSTFDWK-----------------------
>UniRef50_Q2NIN6(82-299:306) Pseudouridine synthase n=4 Tax=Candidatus Phytoplasma RepID=Q2NIN6_AYWBP  E=2e-56 s/c=1.01 id=29% cov=82%
-LDIIYEDPYLAVINKPANLVVHPSLSFQKTTLVNGLLhqfntLSHIDTQRPGIVHRLDKNTTGLLIVAKTNDVSDKLQIAFQQRKITKIYWALIEGFLEDKGIIKLPIGRNNHNRLKMQVMPD--GKTAVTHFKTLQRF-----------SHFSLMECNLETGRTHQLRAHFSFLKHPIVGDLLYDSSHHITPL-------GQFLHSKILKFNHPITNQNLILEAPLPTNFEKLLKTF--------------------------
>UniRef50_C8P3R0(83-303:308) Pseudouridine synthase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8P3R0_ERYRH  E=3e-56 s/c=1.00 id=29% cov=82%
-LDIVYEDDAILVVNKPKGLIVHPSPSTLNQPTLVHGLLAHttqlsdlNGELRPGIVHRIDKDTTGLLVVAKTNEAHEILVEDLKQRLISREYVAIVHHQFKHQsATVDAPIGRDPKN-RQRMAVTDQNSKQAVTHFYLAERF-----------NDFSVLRCKLDTGRTHQIRVHAQYIKHPIVGDQTYSYKNTWET-------NGQCLHAQKLTLTHPVSKEVMTFEAELPQTMKDVIEE---------------------------
>UniRef50_D1U4S9(99-350:596) Pseudouridine synthase, RluA family n=1 Tax=Desulfovibrio aespoeensis Aspo-2 RepID=D1U4S9_9DELT  E=4e-56 s/c=0.87 id=30% cov=86%
-LEVVFEDAHVAVIDKRAGLTTHPAPGEPGPTLVNHLLHRwpdvasdisGMDRQRPGIVHRLDKDTSGLMVVALTEGDRLRLAADFAGRRVRKVYLAVVLGRPAQPaGTIDAPMGRHP-SQKTRMAVVARGGREAVSDYRVLWT---------GPRGLASLVAVRIHTGRTHQIRVHMAHIGHPLLGDSAYGPRENVEWSRRPDRLaglaPRQMLHAFHLSFRHPATCERVTLWRRPPADFCTLLAAL--------------------------
>UniRef50_O67638(82-316:316) Uncharacterized RNA pseudouridine synthase aq_1758 n=3 Tax=Aquificaceae RepID=Y1758_AQUAE  E=2e-55 s/c=0.93 id=27% cov=86%
-INIIYEDEDIAVVEKPCGLVVHPSPGYTSGTLVNALLYHikdlssIGGVERPGIVHRLDKETAGVMVIAKNNTAHRNLVRQFQERKTEKFYKVLVKGLVKKDyGAIDTPIARHPVDRKRFWVRKE--GKEALTEYWVLKRYEKYEI---------TLLKVKIHTGRTHQIRVHFASIGHPVLGDRTYGFKSSSVPKELLSLMgECNMLIAYHLGFYHPTKGEWMVFEIEEPETFKSVYSWL--------------------------
>UniRef50_B6TXP4(138-423:439) RNA binding protein n=3 Tax=Poaceae RepID=B6TXP4_MAIZE   E=2e-55 s/c=0.76 id=28% cov=87%
-LDIVYEDDHVLVVNKPAHMVVHPAPGNAKGTLVNAILHHCKISTftclarssagdecpdssdedtdvfhvdqfaaedvssevrnalvRPGIVHRLDKGTSGLLVVAKDEHSHARLAEQFKLHTIRRVYISLTCGAPnPNSGRIEASIARDPNNRIRMTAIAGSGhryARNAASRYKVREVF---------AGGGSALVEWRLETGRTHQIRAHAKYIGIPLLGDETYGGtqsmalslLRPRSPSKYHSGLsnllskvDRPCLHAASLGFKHPRSGKVLEFSCPPPDDFLEVLGEL--------------------------
>UniRef50_A7I2U9(90-337:357) Pseudouridine synthase n=23 Tax=Campylobacterales RepID=A7I2U9_CAMHC  E=4e-55 s/c=0.88 id=26% cov=91%
-IEILYEDDDLLVLNKPSGVVVHPAKSVKEPTLAEWLKQKKYmlssinGDERAGIVHRLDKQTSGAILVAKTDFAHVKLAAQLKDKSMGRIYLAFLDLALKENVCVDRFIARNPSNRLKKAVVPpnENGARSAKSAFLNIANDTILQNFKPlnfsQNQTNFNLIAAKLFTGRTHQIRVHLSSINRHIIGDFLYGFKSDFDK------IKRIFLHAYLLYFTHPRTNRQILISAKIPSEFKNLIEKSDFKDEIYE------------------
>UniRef50_A4J479(84-298:303) Pseudouridine synthase n=1 Tax=Desulfotomaculum reducens MI-1 RepID=A4J479_DESRM  E=3e-54 s/c=1.00 id=33% cov=82%
-LNILYEDAHLLAVNKPPGMLVHPLTNETSGTLangVLYHWLQQGTIDRFRPVHRLDRNTSGIVLIARNPYVQQQLQIQMKQGQFVRRYLALVKGKVqPEQGVIQAPIALEEGSFIKRMI--SPAGKEAISHYQVLRTF-----------NQASLVRVELETGRTHQVRVHMAHMGHPLLGDSLYGGDTSN--------IKRQALHCAYLAFNHPVQGSRIKISCSVAGDIRQLMEE---------------------------
>UniRef50_Q2GGY1(96-332:337) Pseudouridine synthase n=13 Tax=Rickettsiales RepID=Q2GGY1_EHRCR   E=4e-54 s/c=0.90 id=24% cov=86%
-ISVVYEDHDIIIINKAPGITVHPGAGTNNNTLVNALVAHYGNSlshvgkaTRPGIIHRLDKDTSGLMVIAKNEKSYYFLSDLLLKKQIKKEYLAVVWGlpNPKSNTIKNYICVKPNNKQMMTVTHLPHKGKLAITEYQTQKSF----------SNIASLIKCRIHTGRTHQIRVHMSYIGNSIIGDQKYGKNNSKSVKYAKQStiintLKRQALHAYKLGFTHPTSNTYIEFHSYIPNDIQMLIDEL--------------------------
>UniRef50_B5ZBC1(79-295:299) RluA n=15 Tax=Ureaplasma RepID=B5ZBC1_UREU1   E=5e-54 s/c=0.98 id=27% cov=83%
-LEIVFEDQDLLVINKPSGMLVHPTSFQEQNTLANALK-HYLKTDDFYITHRLDKNTSGLIVICKNQKALCCLQQQFMQKTVKKSYYAIVHNRFDMHHLHfmiNEPIGHSYQDKLRMKTGDAKNVKEAISIVKVIEQYQ-----------NTALVEVSIITGRTHQIRVHMRHINHPIYNDPLYGISKHTTPYE-------QYLHSFYISFIHPSTNEIVEFKTLMPNEFINLIKEW--------------------------
>UniRef50_C9RQF0(78-315:424) Pseudouridine synthase, RluA family n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RQF0_FIBSS  E=5e-54 s/c=0.89 id=26% cov=85%
-LNIVYEDDDIVVINKPRNLVVHPGNGVSKGTLAAALLYHFKenlstvnGPLRPGIVHRLDKDTPGLMVVAKNDAAHRHLAHQLETRTLHRTYNALVWGCPRDlEGTIDAPIGRNPKNRLKMAVV--KGGKESRTHY-----------VAKQFFAIATLLELQLESGRTHQIRVHSRYTGHPVVGDPLYDGRDESlnrvpplmKPVAEKVLeiAPAQLLQAVKIELIHPRTNKKLTFKVPMEEPFANVLKLL--------------------------
>UniRef50_C7GZW0(94-311:318) Pseudouridine synthase n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7GZW0_9FIRM  E=7e-54 s/c=0.97 id=27% cov=82%
-IEInaVYEDEHLLVIDKPAGIVVHPTHGYEENTIAHALiHYMDTVGEefKIRFINRLDMDTTGLLMIAKNQFIQNAVVSEMKRGNVEKRYLAVVHGLPcNREGIIDAPIKAVEGEPRRQVM---EGGKPSITEYKVV---------GVSDELNVSFLDVRLHTGRTHQIRVHLKHIGCPILGDEFYGGKES---------ADRQLLHSRYLRFTHPVSKKIVELTANLPDDIASILTH---------------------------
>UniRef50_Q211J3(264-488:501) Pseudouridine synthase n=81 Tax=Alphaproteobacteria RepID=Q211J3_RHOPB  E=2e-53 s/c=0.94 id=31% cov=85%
---ILYEDADVMVLNKPAGLAVQGGSGTTRHVDLMLEVMRDAKGQKPRLVHRLDKETAGCLLIAKTRFAATALTGAFRERSARKVYWALVAGVPkPKQGRISTYLAKEEsedDTIMRIAEHGDEGASHAVTYYAVVET----------SASKLAWVSLKPVTGRTHQLRAHMAHIGHAIVGDPKYFNIENWQLPGG--LQNRLHLLARRIVIPHPRGG-TIDVSAPLPPHMLQSWNLLG-------------------------
>UniRef50_D2RBY1(92-316:321) Pseudouridine synthase, RluA family n=1 Tax=Gardnerella vaginalis 409-05 RepID=D2RBY1_GARVA  E=9e-53 s/c=0.93 id=33% cov=83%
-IPIIYNDDDVVVIDKPVGVASHAAKGWSGPTVpECLEAVGIDIKTTLcdesrkGIVSRLDVGTSGLMLVCKTDFAYEVMKNQFAKHIVKKTYHALVQGDLAQDkATIDAPIGRAKVSDFRFTITSD--GKPAVTHWDVLERF-----------SQATLVSVNLETGRTHQIRVHFSSIGHPLVGDSMYG---ANPVLAQKLGLQRQWLHSMELTFTHPRTGKSVTVKSHYPLDLQHALE----------------------------
>UniRef50_B5JUW4(96-315:321) Pseudouridine synthase n=1 Tax=gamma proteobacterium HTCC5015 RepID=B5JUW4_9GAMM  E=2e-52 s/c=0.95 id=31% cov=85%
---ILFEDERLLVINKPSGMAAHAGSGVPFGIAEAVHQHHC-DGKRTELVHRLDRETSGCLLLAKGRSVLNVLQDSFRQRETHKQYLALLVGDLKGSRRVDLALQKTKLS-GEAMVVVDEAGKSALSDFEPLAHY-------PWNDRTLTLARVTIHTGRTHQIRVHARALGLPLLGDDKYGDERLNRD-AKRQGLKRLFLHAESIRF--PLEGQTLYFEAPLDADLEQFINAL--------------------------
>UniRef50_C6D874(113-330:332) Pseudouridine synthase, RluA family n=2 Tax=Paenibacillus RepID=C6D874_PAESJ  E=2e-52 s/c=0.95 id=31% cov=83%
--EVLYEDDFSLVLNKPAGMPVHESHSGQTGTLdeaAARWLLEQGDPLPVRHIHRLDDDTSGPVLYSKNDLAQWVLDEAMREKRIDRRYLAVVQGKVKKsSGTVNAPIGKDRHHSSRR--RVTPGGDLAITHYETIRAF-----------SDATLVRLQLETGRTHQIRVHMSHLGHPLLGDKLYGG--------DTRLLQHQALHGERLLFPHPWTGELVEAAAAKPEWLVNLLDKLGGR-----------------------
>UniRef50_Q67N67(74-316:327) Pseudouridine synthase n=1 Tax=Symbiobacterium thermophilum RepID=Q67N67_SYMTH  E=3e-52 s/c=0.85 id=31% cov=83%
-IQVVYEDPWLLVVDKPAGMVVHPVRDYVSGTLanaVAHHLLRSGSDPVARPVQRIDRETSGLVLFAKDPAVAGLLARELERQKLERRYvAVVEGAVAADAGTVDRPIRRVWGHPVAREVAEGPrtpeqerllaeaaaqgralredwtaAGQPAVTHWRVLRRW-----------PAATMLELRLETGRTHQIRVHMAYLGHPLLGDELYGGSR--------TLIQRQALHAATLAFVHPVTREPVRFTAPLPADLEDLVARL--------------------------
>UniRef50_B8DF66(78-287:289) Pseudouridine synthase n=18 Tax=Listeria RepID=B8DF66_LISMH   E=6e-52 s/c=0.98 id=33% cov=80%
-LEIIYEDDFLLVVNKPVDMKTHANDSYETDTCANavqYYLEKTGQDANALAVHRLDQTTSGLVLFAKNKLAIAGLSWQMENRAIHRTYLAAVDGTWGlVMQTINKPIGEDRHHGSRRQI--SPYGQPAVTHVKVLE---------NDNEKNTSLVECQIETGRTHQIRVHLSGIGHPIIGDTLYGG---------SPRANRIMLHAEKLHLNHPFKGKEMNFSAPAGDDW---------------------------------
>UniRef50_D1BN73(79-323:324) Pseudouridine synthase n=3 Tax=Veillonella RepID=D1BN73_VEIPT   E=6e-52 s/c=0.84 id=28% cov=85%
-LDIIYEDEYILVINKAAGILMHPTSTIRDHTLangVLHYYQETNQHYDFHPVHRLDKDTSGIVIIAKTSVVQHAFDK--KHTHFYKSYDAIVEGHLPSVPIsINWPIGRKPGSIIERCCTVQ--GKPARTDITIISKNTSKISSGKINSDDvitlnnnsnicstdssltsysqFTHVKCLLHTGRTHQIRVHLSQLGYPLAGDDLYGGHLES--------IQRQALHAARVSFYHPITNEWLELHAEMPEDMKVLLN----------------------------
>UniRef50_D1W0M0(351-560:566) Pseudouridine synthase n=1 Tax=Prevotella timonensis CRIS 5C-B1 RepID=D1W0M0_9BACT  E=1e-51 s/c=0.98 id=36% cov=80%
-LHVVYEDDALIVVDKPAGILSVPGRSQRPSVYSILRS-QMPSSVELFSVHRLDMATSGLLILAKNSVVYRHLQRQFRTHHIQKEYIAILEGALSQrEGVVTLPLRPDPFD-RPRQVVDWEHGKKAVTSYRVL-----------NVRHGKTWVALFPETGRTHQLRMHCAHaegLNCPILGDPLYGHH-----------ANRLYLHATSITFEHPISGQLLTLHAQPPADFQDVF-----------------------------
>UniRef50_B5Y8D7(86-304:315) Pseudouridine synthase n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y8D7_COPPD  E=2e-51 s/c=0.94 id=26% cov=82%
---VVYYDEHLAVIDKPPNLVVHPAPSVKGLTLCHGLLKDFpqvknvGSAERPGIVHRLDKDTSGLMLVALSEKGYAGLTKMISEKSVSRKYLVAVYGVANRPFEVDAPIGRDPRNPTRMAVV--PHGKNAYTRFRPVQCLE-----------KVSLLEAELFTGRTHQIRVHLSHAGFYVLGDPVYGNVES------RLLAPRVFLHSYYLELEHPITGERLFFVSPLPEDLDECWHILG-------------------------
>UniRef50_D1Y726(85-308:315) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Pyramidobacter piscolens W5455 RepID=D1Y726_9BACT  E=2e-51 s/c=0.91 id=34% cov=84%
-LDVIYSDRCVMVVNKPAGLLSQPDVKGEDSVVTRALGYAVDPEFPPQLVHRLDRNTSGVMALALDGPTTRALMECFKARRADKRYWAIVIGELPERGRIDVPLLKDAD---KKLVRVDPKGERAVTEYKRL-----------TSSGAFSLAEVHLLTGRTHQIRVHMNHVGHPLLGDVKYGDFGSKGQLR-SLGVKRPMLHARSLTLNglpaflsHLEGK---TFRAPAPDDLRRVMEKLGF------------------------
>UniRef50_Q3A3D8(66-285:301) Pseudouridine synthase n=2 Tax=Desulfuromonadales RepID=Q3A3D8_PELCD  E=2e-51 s/c=0.93 id=32% cov=82%
--HILLRDRYLVVVNKPPGINSQPTPARYKGTLYEALLrllddpYNKGRKPSLGMVQRLDRDTSGVMIFSIHARAHKSLSDIFAARRVQKHYLALVAGCMqAPQGEFRSLLARQHRTNLMK--SVARGGKEAVTRYRVIEKF-----------GDAELLEVEIPTGRSHQIRVHFAEAGHPLLGDIRYGGPDRWRG----VDVPRQMLHARRLELLHPISKEPLNIEAPLPQDFLKLLE----------------------------
>UniRef50_C9KIU1(78-294:296) Pseudouridine synthase n=3 Tax=Veillonellaceae RepID=C9KIU1_9FIRM   E=3e-51 s/c=0.94 id=33% cov=82%
-LDIRYEDDYLLIVNKPAGQLVHPTTKEAHGTLgnaVLYWYKAHGEHHAYHPVHRLDRNTSGLVLIAKVPQVQYKLtPRHGEGKLFHREYLALIEGELtPPEGLIDAPIARALPSIILR--KVSPDGQTARTHYDTVQT-----------DGKLSLIHLVLDTGRTHQIRVHLAHLGHPLLGDDLYGGNLA--------RIKRQALHAARLHFRHPMTGAEIDVQVPLPSDMAQIVSDF--------------------------
>UniRef50_A6LDZ7(340-549:549) Pseudouridine synthase n=26 Tax=Bacteroidales RepID=A6LDZ7_PARD8   E=4e-51 s/c=0.97 id=38% cov=75%
-LDILYEDDYLLVINKPEGMLSVPGKGDADSVYQRLSILYPE-ATGPIIVHRLDMATSGLLLAAKTKEAHQNLQAQFKNRTIQKRYIALLEGEVPQDeGEIRLPLCPDPLDRPRQIVSE-EFGKPALTHYRVLER-----------TSGKTLIAFYPQTGRTHQLRVHAAHplgLHCPILGDELYGRKAE-----------RLYLHAEYLAFTHPITSERIEIQ----------------------------------------
>UniRef50_B2KBB0(77-296:299) Pseudouridine synthase n=1 Tax=Elusimicrobium minutum Pei191 RepID=B2KBB0_ELUMP  E=5e-51 s/c=0.92 id=29% cov=77%
---IIFEDKNMFVINKPSGMLVHPqspvweenpaAAFIGEETLVSLILANPPKNfekgiTRAGLVHRLDKDTSGVMIIAKNSKTQDAMVEMFANREMHKTYEAIVCGVVPDDkGIINVPIGRVTGGKIKA----SELGREAVTEYSVLQRKET-----------VSLMKLHPVTGRTNQLRVHMSWLGYPVLGDWLYKGAT----------APRLMLHSKSAEFEHPFTSKPVKFTVAPPKDFK--------------------------------
>UniRef50_Q2GEQ1(79-323:330) Ribosomal large subunit pseudouridine synthases, RluA family n=4 Tax=Neorickettsia RepID=Q2GEQ1_NEOSM  E=9e-51 s/c=0.82 id=26% cov=90%
-LDVRYEDDCLLVIYKPAGLVVHPGIGNREQTLVNILEHHYPteklsslDSSRPGIVHRLDKDTAGFLIVAKTNPAHLSLSQMIKEGVIRREYLALVHSVPAS---LSGEIKKPIKRGQRKMMIGRCSGKPALTYYGVIA---------RTVDRKCSLVHCRLGSGRTHQIRLHMKSIGCPVVGDKLYGLNRD-----ADLCAPHHALWAYSLQFRHPFTRKNMAFYIEPASIIQPFLEKISISRSLfvtfPEDRRTIRSAQS--------
>UniRef50_B1H0R5(88-293:296) Pseudouridine synthase n=1 Tax=uncultured Termite group 1 bacterium phylotype Rs-D17 RepID=B1H0R5_UNCTG  E=3e-50 s/c=0.97 id=26% cov=79%
-----------VVVNKRSGIVVHPSYGHLSGTLLNALMGYSAGKYNPYLIHRLDKDTSGVIVFAKTEKAKISISKQLQKRVVKKIYYAAVKGVIaENRGIIKAPLGRSPKNRKL-VSVNPLAKKVAITEFKVIERKD-----------DYTLLKVRIITGRTHQIRSHMKYINHPVIGDKQYGGPGTIGLKR----CERQMLHAHNITFTHPSTSKTVKFIAQLPNDMKAIFK----------------------------
>UniRef50_C8NZX3(77-295:298) Pseudouridine synthase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8NZX3_ERYRH  E=4e-50 s/c=0.91 id=25% cov=83%
-IDVVYEDEYLLVVNKPRGLVVHPGNGVKSDTLLhgLLYYLNSNCDHyiRPGLVHRIDRNTSGLLVIAKDDKTHQFLAEQLLDKTMNRTYYALVHGVLPQAHVLIDAPIGPDKSNTKIMTVNQARSKPARTHFEKIETYINS-----------SLICCKLETGRTHQIRVHALHANIPLHGDPQYGHPSDTDKT-------GQYLCAARLEFVHPKYLKLMQFEIPLPRYFQDKITEL--------------------------
>UniRef50_Q5ZT70(91-314:317) Pseudouridine synthase n=5 Tax=Legionella RepID=Q5ZT70_LEGPH   E=5e-50 s/c=0.89 id=29% cov=86%
---IIFEDSSLLVINKPAGIAVHGGSGLSLGVIEALRKTRHDLS-YLELVHRLDRETSGCLLLAKKRSTLRAIQALLEAREVQKIYWALLTHRWdgKKKITITAPLEKNTLKSGERVVSVQKDGKASETDFKLLENY-----------HQACWVEASPKTGRTHQIRVHSAYFGHVIVGDEKYGAKVGEVEGID-YQQNRLYLHARSIQFN--LNGVMHVFQADVDDGFGNTLKQLRARSLL--------------------
>UniRef50_B9JWI8(98-321:330) Pseudouridine synthase n=1 Tax=Agrobacterium vitis S4 RepID=B9JWI8_AGRVS  E=5e-50 s/c=0.89 id=33% cov=85%
----LHEDEKVFVLNKPAGLAVQGGSGLNRHIDQMLEAWTSKKGEKPRLVHRLDRDTSGVLVVARTRGAAQKLTAAFRERDTKKTYWALVKGVPrKHDDKISTWVVKEqtEDGDRMRIARHGEDGaDHAVSYYRVLET----------AAQSLAWLEMEPYTGRTHQLRLHALHIGHPIIGDPKYYIDDPNWDFPGGVQ-KRLHLHARHIDIPHPDGG-RLRITAPLPPHMVQTWNLLG-------------------------
>UniRef50_B9MS57(77-286:293) Pseudouridine synthase n=1 Tax=Anaerocellum thermophilum DSM 6725 RepID=B9MS57_ANATD  E=5e-50 s/c=0.95 id=29% cov=80%
-IDILYEDNFFLFVNKPSGLPSHPSKGHYFDTIANYvEYYLNSKNLTSHIINRLDKDTSGIVVFAKNSYFHSIVSYEFEKRRVDKTYIAIVHGILtKKSGLIEKPIKRSDDGIKREI---HQDGSFASTYYEVIDSFE-----------NFSVLKLKPITGRTHQLRVHLSSIGHPIVGDYIYGEEKTQNTP--------LLLHAYSISFNFkLINNKVYDITSPLPHYFHE-------------------------------
>UniRef50_B1VEM5(95-311:313) Pseudouridine synthase n=3 Tax=Corynebacterium RepID=B1VEM5_CORU7   E=8e-50 s/c=0.92 id=34% cov=82%
--HIVFEDDDLLIVNKPANIAVHVGSGVKAGVIEALRVLRPE-DKELELAHRLDKETSGLLIVAKNSKMLRHLQSLLREGgeDIQRYYLAVAGGVLKKSGKQARRIDAPLRKTGAATVVDRRAGQQAETKLWV----------KKPWGRAGTLVEVQLLTGRKHQIRVHLQHLGHPIIGDSRYGDKAANQAAAEK-GVRMLMLHASRLVIPLP-SGEELDVQAPMPPAW---------------------------------
>UniRef50_P70870(84-306:326) Ribosomal large subunit pseudouridine synthase D n=23 Tax=Borrelia RepID=RLUD_BORBU  E=2e-49 s/c=0.89 id=34% cov=73%
-IAIIYEDSNVIVLNKPQGILSHPGISHWDDTVVNFLLYHikslkinfNEEKIRPGIVHRLDKDTSGVLICAKNISTLRFLAQQFKDKRTNKVYIAIVKGNFNSFFGSIESFIDRDKHNRKKFSVSKDRGKKALTEYRLLLNF-----------GEYSLLALKPKTGRTHQLRVHMKYLNFPILGDEVYGRVDGSLKKIT------LMLHSYKLEI----------------------------------------------------
>UniRef50_D0P480(117-342:363) Ribosomal large subunit pseudouridine synthase A, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0P480_PHYIN  E=3e-49 s/c=0.87 id=36% cov=81%
-LKILFRDDAVIVVNKPANILSV-DGTDPDALMSVHRCV-ARVYPNARMVHRLDQETSGLLVVALTKSAAQSLNAQFRDRSVDKTYVARVDGWMMNDleeksespRRVQIPMEKHLTKSLIQHVVSDREVDPssslwSTTEYSVLSRDES------GDDRKSTLVELKPVTGKTHQLRLHMQHLGHPILGDSLYSPDVV------YHRASRLCLHAAKLSFTHPVTNERLTFESPCP------------------------------------
>UniRef50_Q0ANT2(91-315:330) Pseudouridine synthase n=2 Tax=Hyphomonadaceae RepID=Q0ANT2_MARMM   E=5e-49 s/c=0.88 id=31% cov=84%
---VIYQDDELIAFNKPAGLAVQGGSKTTRHLDGMLDAFGEGLD-RPRLVHRLDKDTSGILIVGKGPKATARLAKAFQSHKTRKTYWAIAIGVPKPKMGEIKGFMRKaaasgvdsERETMVAAGHGDEGAQHALTRYVVIGE----------AGQKASWVALRPVTGRTHQLRVHLAAMGTAILGDKKYTCHRP----APEDLGRRLCLHARRLEIPRP-GGKPLVLTADLPPALKKIYDTLGF------------------------
>UniRef50_Q057L6(93-312:317) Pseudouridine synthase n=1 Tax=Buchnera aphidicola str. Cc (Cinara cedri) RepID=Q057L6_BUCCC  E=5e-49 s/c=0.90 id=28% cov=85%
--NILFEDNDLIIFNKPYGFAVHGGSGISYGVIEIFRKIRSDL-KFLELVHRIDKETSGILILSKKRSILKKMHINLREKKIYKEYLAILHGyWSKKNKIVKLPLLKKKNIKQKKKVCVHKEGKLAQTNFEIKKYL-----------NNKTLVKIIPITGRTHQIRVHTAQFGHPIVFDNRYGKIEKKKKKIIKKN-SRLLLHAFKVSFLHPRNNENFSITAPLDKKFQNCLKYF--------------------------
>UniRef50_C6XFC8(102-325:346) Ribosomal large subunit pseudouridine synthase C n=5 Tax=Rhizobiaceae RepID=C6XFC8_LIBAP  E=6e-49 s/c=0.88 id=28% cov=85%
----LYEDSKIYVFNKPAGISVQGGSGIAYHIDGFLKSWVDSKGQKPRLTHRLDQETSGILVVARTRAAAQHLTESFRMRRIQKIYWSLVWGIPKNKKECIANWLLKKSHIGGDYVHVvkqnEKGANYAISHFKVIDCF----------AQKFCWLEMQPHTGRTHQLRVHALHMGCPIVGDHKY--CANFKGNFTSPIQNKLYLHARYMDLPHPEGG-RLQITAPLPAHMVKTWDSLGFK-----------------------
>UniRef50_C6VN18(77-290:293) Pseudouridine synthase n=3 Tax=Lactobacillus plantarum RepID=C6VN18_LACPJ  E=6e-49 s/c=0.92 id=28% cov=81%
-IQIEYEDANWLVLNKPAGLTSVPGPSNRTDTLVNrikgYLIASHASNQRPHLITRLDRDTSGLVLVAKHRVAQGMLTEPRIAAQLVKTYQAWIEGTItPASGTIDRPIGRVADSPRR---VVTTAGQRAITTYQV---------EADQLQHNVSRLRLELVTGRTHQIRVHLTALGHPLLGDTLYGGNLAW--------IQRQALHAASLQFFDPFSEQTLHFEAALPADLQAL------------------------------
>UniRef50_D1RB93(68-280:283) Pseudouridine synthase n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1RB93_9CHLA  E=7e-49 s/c=0.92 id=31% cov=82%
-VPILYEDAHLVVIEKPAGLLSVATNFDKAKTAHAFLKERYR-PRKVYVVHRLDQDTSGVMLFALTGEAFFGLKALFADHDIDREYTAVVHGKMTqQEGTWQSYLYEDKAYVVHSTQDPDK-GELAITHFKTVE-----------ARTHFSLLNLKLETGKKNQIRVHCEDHGFPIVGDKKYGGE------GESHITKRLCLHAHHLGFVHPIYKKEMSFDSPIPEKFYQCLK----------------------------
>UniRef50_D2EJM0(86-291:304) Pseudouridine synthase n=1 Tax=Pediococcus acidilactici 7_4 RepID=D2EJM0_PEDAC  E=1e-48 s/c=0.95 id=29% cov=79%
--DVLFENDDLLVVNKPAGIKTHANQPHELGSMINfLQAYFAKKDSNAYNVHRLDQWTSGALLVAKNPVVVPILSRQISQKLIQRTYLCVVEGHLKsRSGTITLPIGLDPHDQRKR-QINGPGAQPATTHYQVVREFVER-----------SLLRVQLATGRTHQIRVHLAALGHPIVGDPLYNSLADGAP---------MRLHSWQVKFPLPFSQSWQTVTAPVPNYF---------------------------------
>UniRef50_Q30SG9(78-299:323) Pseudouridine synthase n=5 Tax=Epsilonproteobacteria RepID=Q30SG9_SULDN  E=1e-48 s/c=0.88 id=25% cov=83%
-VEILYEDDDILVINKPTGLTVHPAPSVKEATLVdwlkhkGMRLSSLSGEERHGIVHRLDKGTSGAMVIAKNNSTHEFLSDQLQDKSMGRYYLAVINPPLKDELTEViFPIARSSHNRLKMAPLEH--GKYAKSAFKVLAYSNDEANQ---------LIACKLYTGRTHQIRVHLESLNRHIVGDHIYAQSPKQEKSE------RILLHAYIIYFIHPKSKERVSFVASLDKGMQEYIDK---------------------------
>UniRef50_D2R4N0(89-312:313) Pseudouridine synthase, RluA family n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R4N0_9PLAN  E=2e-48 s/c=0.87 id=31% cov=83%
---IVYEDRHLIVVEKPAALLTVPTPKNDRGTLlerVANYVKIVSRGKGAFQVHRLDRGVSGLLIFGKTTELAQMLRDQFAMHKPEREYVAIVRGKLDKPEGMIESFLATDRDLNRYSTDDESIGQHAVTHYRVIEEL-----------AGASVVQVWLETGRRNQIRVHFAEAGHPLIGDQRY---RADEAADTRWTHARIALHARLLGLSHPMTGEPLRFESPLPHEMKNFI-----------------------------
>UniRef50_Q03H72(87-291:296) Pseudouridine synthase n=1 Tax=Pediococcus pentosaceus ATCC 25745 RepID=Q03H72_PEDPA  E=3e-48 s/c=0.95 id=29% cov=78%
---ILYENSDLMVVNKPTGVKTHANQPHELGSMMNfLQAYFKDTENEAYNVHRLDQFTSGALLVAKNPVVVPILNRQISTKVINRTYLCVVSGHLEQsKGTINVPIGFDPDDKRKR-QINGLNPLSAITHYQVLAQYENS-----------SLIQVDLETGRTHQIRVHLSYLGHPIIGDPLYNLDNTQQP---------MLLHSWKIRFPLPFNLETIEVTAPIPDYF---------------------------------
>UniRef50_Q1D9A6(82-316:316) Pseudouridine synthase n=2 Tax=Cystobacterineae RepID=Q1D9A6_MYXXD   E=3e-48 s/c=0.83 id=31% cov=87%
-LTVLHEDDSLVFVDKPAGRPSHPLQSGETGTVANALvarypecALASLDAREGGLCHRLDVETSGVVVAARTRDAWNAVREAFGSRAVDKRYLALVTGPLTDEGDIDLPLRHHPRHPDRVEPAPygAEDARDAVSKFTVLSR-----------SGEFSVVEVKILTGVLHQVRAHLAGIGAPIVGDSLYGG-------REAPELGRFFLHARSLGLTHPQTRRNMTVHSPLPPELRAELERRGL--PLPRGEQRD-------------
>UniRef50_C0WQF4(79-293:297) Pseudouridine synthase n=3 Tax=Lactobacillus RepID=C0WQF4_LACBU   E=3e-48 s/c=0.90 id=27% cov=81%
-IQIVFEDEHFLVVNKLSGIASVPAHNRANDSLVNrvkgYYQRNHYANQKIHIVTRLDKDTSGLVIFAKHHFAHSVLDKQLKDHQIKKTYLAIVEGTFsTTHFEIYLPIKRADGSLVKRQV--GFPGKMSITE-----------AWTKQRLRQHTLLKLQIHTGRTHQIRVHMTAIGHPLVGDWLY--------NPEDKSFPRQALHCAGLRFFNPFAGHFVDCRAPLPDDMKTYLA----------------------------
>UniRef50_B1MWE1(87-304:306) Pseudouridine synthase n=3 Tax=Leuconostoc RepID=B1MWE1_LEUCK   E=4e-48 s/c=0.89 id=31% cov=81%
-LDIIFENDDLVVVNKPAGMKMHPHSPSETDTLLNFlaanfskrHLYSAGAIAKPYMVHRIDRETSGAVIVAKNPVVVPILNRMLKEKVIQRTYLAWVQGIlLKNSGTIDRPIGRDISKPFQRQVNGVQ-AQHAKTHWFKIHTVFQN-----------TLLRLQLDTGRMHQIRVHLASINHPIVGDSLYG---------QRLNQQRMMLHAMSLTLPLPFDGPKRIITTSLPSDFPKQL-----------------------------
>UniRef50_D1R6W7(83-294:295) Pseudouridine synthase n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1R6W7_9CHLA  E=9e-48 s/c=0.91 id=28% cov=80%
---IIYEDADLLVYDKPAGINC--------DTSGIVRLIH-QKDPSLKLVHRLDRDTTGILLFAKTDAVLHKMIRLFKTFKVKKTYYVIVDGAIsKEKGVIDNNLAPLHKYQGQTVWGQATGSKgvHARTGWR-----------KEKKGQDCTLIQCYPVTGITHQIRVHMSEMGHPILGDYQYG-----RRFICSYQPSRYLLHAYEITFPHPSSEKEIRLKAPLPSDFKQALDHL--------------------------
>UniRef50_A9GHW4(113-347:356) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GHW4_SORC5  E=1e-47 s/c=0.82 id=28% cov=87%
---VVYADASVVVVNKPAGVSTIPygdeapaeqaATLDALVREVLARRDRLRGRAPLGVVQRLDKGTSGLLVFARTLAAKKHLAQQLRVRAMHRQYLALAHGAVP-RGTYRSYLVEDRGDGLRGSARDgRREGQLAVTHVEPIEVLRGPQEGAG--AGGVTLVACRLETGRTHQIRIHLAEAGHPLVGETVY----VRDYRGTKVPAARLMLHAAELGFDHPADDRPMRFQAPPPPDFDDVLERL--------------------------
>UniRef50_B1CC12(97-302:305) Pseudouridine synthase n=1 Tax=Anaerofustis stercorihominis DSM 17244 RepID=B1CC12_9FIRM  E=3e-47 s/c=0.92 id=27% cov=77%
------------VINKKPGMVVHVTKSHPLDTLQNAIYHKweiEKKHFKTRFVNRLDMDTSGIVVIAKNKYVHHFIQNQSINNQIDKKYVLIVDGIMDQkEGYINAPIKRAEGHPLRRIVAED--GKECITKYKVIEEFK-----------NHSLVEAKLITGRTHQLRVHFSYVGHPILGDSLYNENK-------SELISHQALHAKSISFVHPRGNKPMTFEAELFDDFKDVLE----------------------------
>UniRef50_D0XS67(113-333:350) Pseudouridine synthase n=1 Tax=Brevundimonas subvibrioides ATCC 15264 RepID=D0XS67_9CAUL  E=5e-47 s/c=0.86 id=33% cov=84%
---VIYEDDLVIALNKPWGLAVQGGTKTTRHVDRLLSAWGEGM-ERPRLVHRLDRDTSGVLLLGKGPEAAKRLAGAFARRQAKKTYWAIVMGLPkPADGQISVHLKKSGINdyeIMRPADPKDPGAEPAETAYAVISH----------AAQRASWMALRPFTGRTHQLRAHMKAIGHPILGDPKYGDDASTQLSGPLK----LQLHARRIELDHPAGG-TLVVEAPISAELRAGFEHFGF------------------------
>UniRef50_B4UM41(84-295:302) Pseudouridine synthase, RluA family n=4 Tax=Anaeromyxobacter RepID=B4UM41_ANASK  E=1e-46 s/c=0.89 id=33% cov=79%
----LYADADLCAVDKPAGVPAQPTLTTDRG--ALPELVSALLGAPVTLVHRLDRETSGVTVFARTRDAAAALAEAFRTGTPEKTYLALCARAPsPAEGRVALALGKDPARPGLR--RVDPAGDPAATRYRTLREA-----------PGGARVEARPETGRTHQIRVHLAALGAPLLGDARYGGPRRVGEVA----VPRVMLHATRLELPHPATGARMVFEAEPPEDFR--------------------------------
>UniRef50_A3MZ33(32-233:237) Pseudouridine synthase n=9 Tax=Proteobacteria RepID=A3MZ33_ACTP2   E=2e-46 s/c=0.93 id=36% cov=77%
----VYRDNHILVINKPSGLLSVPGNRPEYYDSAMTRVQQKYGFTEP--AHRLDMATSGILLFALSKAAEKELKRQFRDREPKKHYIALLWGKLGEKvgdtGEMNFPLICDWENRPRQKICYER-GKKAITHYEVLAHL----------PNNTTRVKLTPITGRSHQLRVHSLALGHPILGDKFY------ASPLAKSLSPRLCLHAESLSITHPITGEAMTFTA---------------------------------------
>UniRef50_Q9ZL98(78-313:327) Uncharacterized RNA pseudouridine synthase jhp_0682 n=15 Tax=Helicobacter RepID=Y745_HELPJ  E=4e-46 s/c=0.79 id=24% cov=87%
-IEVIFEDEDLLVLNKPPNLVVHKAPSVKEPTLVdwlksqNYELSNLGLKERYGIVHRLDKDTSGGIVIAKNNFTHVCLSEQLKTKMMGRYYIALLSTPLKEEKMsVECYLTRNPNNRLKMIALkaaKKEKSRYSKSEFTSLLT----------SQNGMDLIGAKLFTGRTHQIRAHLEYLNRHIIGDNLYGLNGVLSKEEI-----RIMLHAYLIEFKHPRSEQKLRFKVPLLKDMLEYLKKVFDKENLDE------------------
>UniRef50_A3DC38(9-221:231) Ribosomal large subunit pseudouridine synthase D n=9 Tax=Firmicutes RepID=A3DC38_CLOTH  E=5e-46 s/c=0.87 id=27% cov=80%
-IDIIFEDNHLLVVKKPVNIPTQKDKSNDSDMLTLLkedikKRYNKPGNVYLGLVHRLDRPVGGVMVFAKTSKAASRLSDQVRTRQFKKVYLAVVHGILdKLEGRLENYLLKDTRNNTVSVVKEDtPGGKLAVLDYKV-----------EGIYNGFSLVKVSLHTGRPHQIRVQLANIGHPLYGDQKYGHGVNKPG-------QQIALWSSEIAFVHPVLKQEMIFSCEPPE-----------------------------------
>UniRef50_A7K2Y9(14-245:250) Pseudouridine synthase n=4 Tax=Vibrio RepID=A7K2Y9_VIBSE   E=8e-46 s/c=0.80 id=28% cov=89%
-VDIVFEDDDILAVNKPSGLLSVPGRLAEH--YDSMWSRLKEVHPEIQVVHRLDMSTSGLMLLAKNKPSERALKKQFQYRLTHKVYYARVWGHVePQEGNIDLPLICDWPNRPRQKVCFD-DGKPSQTLFQVVKR------EVHSDGTHTTVVRLLPITGRSHQLRVHLMAIGHAIVGDEFYATEEAYQFSE------RLELHAAELSFYHPATDQLSSIFVPC--DFYPEAEAMIFNYFSPERTLPDYK-----------
>UniRef50_Q2LVB7(107-316:324) Pseudouridine synthase n=1 Tax=Syntrophus aciditrophicus SB RepID=Q2LVB7_SYNAS  E=9e-46 s/c=0.88 id=32% cov=79%
-FPVLFEDQHVIAVEKPVGIATFSADGSASVQWIVAQALKEHSRGKIHafAVHRLDKEVSGVLLFAKSKMAMDHIKE--KWKEAEKRYYALVEGKPEsPDGTIESWLVEDHAQKVHST-RESSKAKFSVTHYRIIKQV-----------NQYTLLDVKLQTGRKNQIRVHLSDIGCPIAGDRKYG--------AAADFVRRIRLHAYYLSFPHPVTGERISIESPMPEGFL--------------------------------
>UniRef50_Q31HX2(29-228:241) Pseudouridine synthase n=1 Tax=Thiomicrospira crunogena XCL-2 RepID=Q31HX2_THICR  E=9e-46 s/c=0.93 id=31% cov=77%
---VLYEDDDIIVVNKPAGLLSVPGKDLDPEMNLLAQVQKH--VPTALIVHRLDMDTSGIMILAKHKASHRHLSIQFQDRLTEKTYQAICFGKPsTSQGHLNLPMRCDWENRPLQI-IDLKQGKAASTHWKLTAQYDNAFE-----------VNLTPVTGRSHQLRLHMKMLGHPILGDNLYADPQSFAAS------KRLLLHAASLKVTHPVTKKTMLFEHP--------------------------------------
>UniRef50_C5SM25(65-285:286) Pseudouridine synthase n=2 Tax=Caulobacteraceae RepID=C5SM25_9CAUL   E=1e-45 s/c=0.84 id=28% cov=83%
----IHEDGVIMGFNKPSNLSSQGGRGNFHNLDDMLWAFARSNGNKPRLLHRLDRDTSGIILAAKTRTSAAFVGNAIAARDVHKAYVCIVAnpHNLKDEGVIDAPLRREEIGREaysRICDPHHPDALTARTIYRVVSRTDTS-----------ALVQCEPFTGRMHQIRVHMAHLGCPIAGDVRYGG----ALSLDGLRVPRLMLHARAIDFPHPDGGRR-RWEAPPSPDIQALCKGLG-------------------------
>UniRef50_C7QW59(344-545:551) Pseudouridine synthase n=5 Tax=Cyanobacteria RepID=C7QW59_CYAP0   E=1e-45 s/c=0.92 id=32% cov=76%
-IKVIYEDQWIIAIDKPSGLLSVPGRYFETFDSVLTRLQNSLPDaQELRTVHRLDQDTSGILLLARDRYTHRHLSQQFAQRKVEKIYEAILAGsVMMNEGVIQLPLWGDPNN-RPYQKVDWELGKPSITQFKVITTQE-----------NLTRIQFIPLTGRTHQIRVHAvdtQGLGSVILGDYLYGCNA---------GVSRLHLHARELKFEHPQQQKTVHL-----------------------------------------
>UniRef50_A5ZQH2(42-286:288) Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC 29174 RepID=A5ZQH2_9FIRM  E=3e-45 s/c=0.75 id=29% cov=88%
-LDIIYEDTDILLINKPAGMLSQPDDTKEPSMVEYLIGYLLQNGSlteenlrtfHPSVCNRLDKNTSGVIAAGKSLAGLQELSTLFHDRTVHKDYLCIVKGKLTRSRHIRGYLHKDANlNKVSVSPTKEKDAQPIETQYTPI-----------CNNEHATLLKVRLITGRTHQIRAHLASEGHPLAGDAKYGSQEFNRYFRDHYGLKHQLLHAYRLTFPelegklHNLSEK--HFEAVLPVQFQHILKEEHLEECSYEN-----------------
>UniRef50_Q04TZ1(86-376:377) Pseudouridine synthase n=4 Tax=Leptospira RepID=Q04TZ1_LEPBJ   E=3e-45 s/c=0.63 id=33% cov=86%
---ILYEDEFFVAVDKPGDLPVHPAGKYRKGNL-LTLLKESGKFENLFTVHRLDRETSGVVLFAKDSKAASLLSGLFSSRKIQKYYITKVYGDFPRRKIAYGVLKPDVSSIIRKKRKffllksnflkrnkkyflensFSPEEEFCLTAFRKIESYfiktqfqeiesdvgelkvrsrkkklnfeslqtqneknEEPKVRSIYPKHEfYSFVLCKPITGRMHQIRAVLYGLDFPIWGDKLYGKDEEvflefiegkNPDLTERLGMERQALHAYAIRFNHPITNRKMKIVASVPKDF---------------------------------
>UniRef50_D1BPK7(78-285:288) Pseudouridine synthase n=3 Tax=Veillonella RepID=D1BPK7_VEIPT   E=4e-45 s/c=0.88 id=30% cov=79%
-ITVLYEDAHTLVVNKDPFMLVHPAGQTKSCTLSNYvagYYAKKNVVHKVRPVHRLDRDTSGCILFGKTKEAQQYYTDELQAGRIDRIYTGLVEGRIDANGMVDAPIGVDPVFDNRR--VIDELGQPAQTEYIVLDH-----------EGDNTLLRFKLLTGRTHQIRVHMEHIGHPIVGDAMYGTRNKPYI--------RQCLHASELTFV-PYGKdEAITITCEVGDNF---------------------------------
>UniRef50_C8P137(71-280:291) Pseudouridine synthase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8P137_ERYRH  E=5e-45 s/c=0.87 id=28% cov=80%
-LQILYEDKDILVVDKPYKLLTVSNRKEEELTAFRLasdYVKKQDSKNRIFVVHRLDQDTSGVLMFAKSEYVKRLYQDKWSELVDERLYVAIVEGVVPKDKDVIRSFLRQNKTT---HMYSTSSGQEAITNYEVIKRTENN-----------TILKIQIDTGRKNQIRVHMNDIGHPIIGDKKY--------DAKTNPLKRLGLHAYRLRVMNPKTKKMMTFVSPLPPKFKKL------------------------------
>UniRef50_C0WQT7(87-293:302) Pseudouridine synthase n=3 Tax=Lactobacillus RepID=C0WQT7_LACBU   E=6e-45 s/c=0.88 id=26% cov=79%
-LKILYEDANLIVINKRRGNKTHPNqPGEVGATINHLAAYLKTKEALPYMVHRLDQETSGAILFAKNPAVVPTLVAKIATKNIKRTYLAWVVGTdIDSQGIIDFPIGLDPNDKRKRMIDGNHPAK-SITHYTVLQK-----------EDGYSLLAVQLETGRTHQIRVHLTAIGHPLVGDPLYNPDDKHPF---------LLLHSWKLNIPLPFSEQVIEITAPLPAHF---------------------------------
>UniRef50_A6GAA8(88-305:311) Pseudouridine synthase, RluA family protein n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6GAA8_9DELT  E=1e-44 s/c=0.83 id=31% cov=83%
----VHRGEDFVVLDKPAGVPVSAVRETCVGSLSeaLIHQLESEGLERPYvgVVHRLDQGASGLVLFTIRDVANKSLHKQFRDHEIRRGYRVRVTGEPPAQLRCDAPLIKLRSGGVKVGSPGDGRSKPATTHFRHVARVDGEAGPEH-------LLDVEIETGRTHQIRAHAAHLGFPIVGDRRYGADGEGEAGSDH---SRLCLHARSLEFEHPLTGAPQSFTCELP-DWAQ-------------------------------
>UniRef50_UPI0001978015(97-335:359) ribosomal pseudouridine synthase n=1 Tax=Helicobacter cinaedi CCUG 18818 RepID=UPI0001978015  E=1e-44 s/c=0.76 id=27% cov=85%
-IDILYEDDDILIINKPPHLVIHDAPSVKDLTLTQWLKLHAHtlhtlsGRERYGIIHRLDKQTSGVLCIAKSLLAYEILPNQLKSRQMGRYYLAIIDTPLKQNLQVQCFMGRCPTNRLKMSKIHidenenpPKGVRDSKSSFVKLATSNDGLLE---------LIAIKLHTGRTHQIRTHLESLSRHILGDSLYGYKPSAKSF---FYEGRILLHAYILYLAHPKNGQNHTFKAPILLDMLEFIQ----------------------------
>UniRef50_C8WWB4(86-298:303) Pseudouridine synthase n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WWB4_ALIAD  E=1e-44 s/c=0.85 id=30% cov=80%
-IDILYEDDEIVAVNKPVGVLTHPADGEYKTSLAaqveayVYDRGAREGAFRAAPVHRLDRNTSGVVVFAKTARAAKAWADAFHRGEVEKEYLAIVEGEWSGRGR----VAVDVRREGNVTRVVDDSGKPSETAYEVVAS-----------SRGTSLVRLHLLTGRTHQIRVHMAHLGHPLLADRKYGARPIRGESF--------YLHAHRVRWN------QVHVTAPLPDRMTEKLRTLGYK-----------------------
>UniRef50_C6BRU5(6-213:214) Pseudouridine synthase n=1 Tax=Desulfovibrio salexigens DSM 2638 RepID=C6BRU5_DESAD  E=3e-44 s/c=0.87 id=34% cov=78%
LLDIVYADRKIVVVNKPSGLLSVPGRGPENQDCVVTRVQKMFPECRKFPaVHRLDMDTSGLLVLGLTARAVRELMEQFQKRQVKKRYEALLEGIVKEDSGVIEMAFRLDPYNRPYQVYDPIHGKLGITHWRKLGV-----------ENGMTRVEFTPLTGRTHQLRVHSAHpqgLGCPIVGDRLYGSGTEPGQLK---------LHAGYLCFEHPKTKEKMEFEiAPL-------------------------------------
>UniRef50_C2ELY9(91-305:310) Pseudouridine synthase n=10 Tax=Lactobacillus RepID=C2ELY9_9LACO   E=3e-44 s/c=0.84 id=29% cov=80%
--PVL-ETKNYIVLDKPAGVLSIPSRYEDNDAIVNRLmgyfAKKNMSNLKPHVITRLDRDTSGLVLVGKNAIAHARFSKIGKEKFVKK-YHAIVHGNFSEDkltGVIDAPIGKKGSGVKRAVV---EGGKKAQTKYRVLKQV-----------SGASLVELRLLTGRTHQIRVHMAYLGHPLYGDHLYG---------IEDDFSRQALNCFYLSFPDPFDNEKIkEISIEEPTDMNELWQK---------------------------
>UniRef50_A3I3R5(76-276:279) Ribosomal large subunit pseudouridine synthase n=2 Tax=Bacillaceae RepID=A3I3R5_9BACI  E=1e-43 s/c=0.89 id=30% cov=77%
-IDIVYEDDHCLIVSKPKGMATHPNDDRDTHTCMNhvIAHIQQQGGMYAEHVHRLDKGTQGLLLVAKHPLAKSIFDRMIEEKSIIRTYAAEVQGNIRsSSGTISESIGKDRHHASRR--VVSKTGQHAVTHYEVVSRYKNS-----------CVVHLILETGRTHQIRVHLAYIGHPIIGDTMYGARETVSDDYE--------LHAIQLEFDHPFLNKRITVK----------------------------------------
>UniRef50_B4WMC0(81-325:328) Pseudouridine synthase n=1 Tax=Synechococcus sp. PCC 7335 RepID=B4WMC0_9SYNE  E=1e-43 s/c=0.73 id=29% cov=85%
-FDVLYEDEDLWVINKPAGLPVLPSGGFLEHTLLYQLRVRYRDCQSA-PVHRLGRGTSGAMLIAKSHIAKVQLSEQFRKRsanlssnttpntastcTLGKTYRALIApttpDQLRDRFICTYPIGKLPHTRLGYIY---GHLRDAHSHEKTIGPINSMVSRSEGSVLRRrahsTLVEITIQTGRPHQIRIHLAAAGYPLLGDPLYSaGGVPDPHGYALPGDCGYHLHAHRLQFAHPRTGQSIAITAPPP------------------------------------
>UniRef50_Q037L4(73-285:293) Ribosomal large subunit pseudouridine synthase D n=8 Tax=Lactobacillus RepID=Q037L4_LACC3  E=1e-43 s/c=0.84 id=29% cov=80%
-LEVIYEDANWLIVSKPAGLTSVPGPHTPNSSLLNriagYLVEQKIDAPQPAIMTRLDRDTVGLVLAAKHPYAQGRFDQAHQ-RTLTKHYLAVVSGKLPsPKGEIDAPLKLAADGIHR---IVAADGQTALTKYRVLKEKTN------------TLVDVQLLTGRTHQIRVHFASLGHPLIGDHLYGQPDA--------RIPYQALQATRLKFTDPFSEKRITAELPVPALFNQLLTE---------------------------
>UniRef50_B6BGX6(75-279:308) Pseudouridine synthase n=1 Tax=Campylobacterales bacterium GD 1 RepID=B6BGX6_9PROT  E=1e-43 s/c=0.87 id=34% cov=73%
--------DEFVVFDKPSGVLIHP--QNRKTPYSLIDELKYQYGRDANIAHRIDQETSGLVLCAKNKESERDIKMMFEQRDMKKKYLALVHGELKESICIEEPLLRREDEsaIVRMVVKVHEEGKASKTDIRPLKYF---------AETDMTLVECSPYTGRQHQIRVHLFHVKHPIVGDPIYGQSEEDivkfldkeldaEKRIELSGASRLLLHANELEF----------------------------------------------------
>UniRef50_B9XDK1(15-271:283) Pseudouridine synthase n=1 Tax=bacterium Ellin514 RepID=B9XDK1_9BACT  E=2e-43 s/c=0.69 id=33% cov=88%
LIPILYEDRSVLAVDKPAGWMLAPDSWDKTGRNLQLALQsslnagdfwaHSRNIKFLRYVHRLDAETTGVLLLCKSLGALRAYGELFETRSVEKFYLAVVQGIPKQsEWTCKLPLIADPVVKGKMQVVTPGKPlpksdprgpqaelKDAETHFRVIQTLQDK-----------ALVEAQPMTGRTHQIRVHLAASGHPIVGDPLYG----NAPAAASKGAQIIALRAIKLIYWDPFQKRQIRIAAPTDE----FLKMYGFES-------KPVSTPTPQP-----
>UniRef50_A3VN52(97-313:324) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Parvularcula bermudensis HTCC2503 RepID=A3VN52_9PROT  E=3e-43 s/c=0.82 id=31% cov=83%
---VIYEDDDILALNKPAGLAVQGGAKTLIHIDGMLD-VFGEGEARPRLVHRLDRDTGGVLLLAKSRAVAATLSLAFQQHRIGKTYWAITKGVPhPLFGRIDMRIEKAGEPGREKM-RGTEQGQSALTDYQTVET----------AGQKAAFLALRPHTGRTHQIRVHLSAIGTPIVGDRKYGGAGAVLEG----LPNQMHLFCRQMHV--PRRGRpPLVVTADLTGGMATSWSIFGF------------------------
>UniRef50_Q5FSR8(46-261:265) Pseudouridine synthase n=1 Tax=Gluconobacter oxydans RepID=Q5FSR8_GLUOX  E=4e-43 s/c=0.82 id=30% cov=83%
-IPVLLETPRFLILYKPAGLAVHPGPSTQDSVETRLL---PHPRGGPWLAHRLDADTSGCLLVARRKTALIEAQKAFQERQAHKLYWAVVVGDLPQDsGEIDAPLLRQSDASGWRMVV-DAKGDEARTRWRVLGRSK-----------GLCWVELELLTGRTHQARIHCAELGTPILGDPVYGMPAPDGSA-----LPGLHLLARSLELSLPS--DTLSAQAPPPEFMAASLRAMGFES----------------------
>UniRef50_C9LQW6(71-266:305) Pseudouridine synthase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LQW6_9FIRM  E=4e-43 s/c=0.90 id=28% cov=74%
-FTIVYEDEHILIADKKAGLLCMDSTGKTTRTLigEVNEYLADKGEPSAYMVHRIDFNTSGLMVIAKDEESKGILDRMIKERELEKVYLCIVSGVPkKKEGHLIHYLFKDSKQGKVFLSdVPQKGAKSAVTDYHIVKT-----------GQNLSLLECTLLTGRTHQIRSQMAYIGHPLIGDDKYGSKEVNR----RYGEKGQLLHAWKITF----------------------------------------------------
>UniRef50_A8SAJ4(81-303:303) Pseudouridine synthase n=1 Tax=Faecalibacterium prausnitzii M21/2 RepID=A8SAJ4_9FIRM  E=6e-43 s/c=0.79 id=27% cov=79%
-VKVVYEDAFAVVLEKPPQLAVHPTLNYPGGTLANGYaawAAAHGHSPVFRPVNRIDKDTSGLVLAAKNAYAAPLLA-----GGVTKLYYAIAQGALPlGEGAIDAPIGRRGDSIIGRCVTPE--GKPSRTEYTIIKE-----------ENGLSLAACVPVTGRTHQIRVHFASIGHPLAGDDLYGGSRE--------RIARQALHCARQSFavpvytplpdgirvEMPLQLRTVTVESPLPPDMEALFS----------------------------
>UniRef50_C2G4G7(18-242:247) Pseudouridine synthase n=2 Tax=Sphingobacterium spiritivorum RepID=C2G4G7_9SPHI  E=4e-42 s/c=0.77 id=27% cov=82%
---IIHEDENIIVINKPPFIASL---DEREGGEVNILRLAKKYYADAQICHRLDKETSGILLIAKNPETYRLISIEFEKRRVDKTYHAIIEGtHIFQDLKIDLPILNQGNKN---VTIDRYNGKPAETIFNSIQYFKH-----------FTLVECKPITGRMHQIRIHLATQHAAIVGDSMYRGKPvylsqikkrgftLSKDEEEQPIMKRFALHSKKVRFK--VADKSYEFEAEYPKDFAILLKQL--------------------------
>UniRef50_Q2Q0E2(79-292:294) Putative RNA pseudouridylate synthase n=1 Tax=uncultured organism HF10_3D09 RepID=Q2Q0E2_9ZZZZ  E=6e-42 s/c=0.81 id=28% cov=82%
-LDIIFEDDAILVVEKPAGLLSVATDRlevDTLHNRCVEYCRELKKKAWCFIVHRLDKATSGLMVFAKTEDVKRDLQEQFAERLVHRHYVALVEG-VAEPGQAIQHLVEDRNLRVFVSDKKTKTSKHAITTWDILEKGDES-----------TLLSVVIETGRRHQIRVAMAENGTPVMGDTMHG--------ATTNLHGRICLHAVALEFLHPLTDDPIRFESNFNPAWRHGLK----------------------------
>UniRef50_A9KM78(1-213:237) Pseudouridine synthase n=1 Tax=Clostridium phytofermentans ISDg RepID=A9KM78_CLOPH  E=1e-41 s/c=0.80 id=25% cov=79%
MFNILFEDKHIIVCIKPIGVLSQPGQGEGMDMITLLQEYRKNNKEsdYIGLVHRLDRNVGGVMVFAKTELATKKLSVAIRERNFTKEYMAVIHGRPsESSGILKDLMFKDSSKNKSFVVnRMRKGVKEASLEYRTIETIEV-------AKGEFSFIRVKLHTGRTHQIRVQFASRKLPLVGDGKYGGKDNQCDA---------ALWSYRLAFVHPLTKALVDIK----------------------------------------
>UniRef50_C9LLD9(91-293:313) Pseudouridine synthase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LLD9_9FIRM  E=2e-41 s/c=0.84 id=26% cov=77%
---IIYEDEHILIVDKPAGILTQSDNSNELSLNDALLdycHYNNHSTAKPSVCNRLDRNTSGIVLCGKTVKGLQMLNEIIKNRTLHKYYRCIVLGETKEQDTLKGFLIKNESANQVTIITEQKdNAVPIETRYKRISTME-------RAGNICSLLEVRLITGRPHQIRAHLTSIGHPILGDRKY-RNKKSIEISKALHIPHQLLCACSITFP---------------------------------------------------
>UniRef50_D2M3P6(22-299:300) Pseudouridine synthase n=1 Tax=Rhodopseudomonas palustris DX-1 RepID=D2M3P6_RHOPA  E=3e-41 s/c=0.61 id=31% cov=88%
---VLYRDGLMLVIDKPPGLPVHRGPKGGPNLEASFDALRYGLPRPPVLAHRLDRDTSGCLVLGRHRKATATLGLLFKHSRISKTYWAIVEGGPaEDEGSIDLPIGKLNAERGWWQKIDQESGLPSLTKWRVMGRSSPPVcgdgsgvgahsgtpslgrphpgplpqagegalsagakgddlsrkpgaKSGAPPPAQLTWLALEPITGRTHQLRVHCAAMGWPIFGDNIYGNGP-------RFGEPRLHLHAREIVIPLSRNKPPVVVIAPPPAHMHPRLSACGWTGA---------------------
>UniRef50_C4R1Q9(105-285:358) Mitochondrial tRNA pseudouridine synthase involved in pseudouridylation of mitochondrial tRNAs n=1 Tax=Pichia pastoris GS115 RepID=C4R1Q9_PICPG  E=9e-41 s/c=0.93 id=33% cov=65%
--EIVYQDDNILVVNKPCGVPVHPTGKYYYNTMTEI-MKNELGVSSLYPCHRLDRLTSGILIIGKTPRAAAKYQTQLKQNSIQKTYIARVDGEFPMGNIVCSDKIVNIDCKRGKENGITE-PKEALTNFQRLAYSTSLNQ---------SIVKCSPKTGRTHQIRIHLRNLGHPIANDPLYG------------------------------------------------------------------------------
>UniRef50_A5E2D2(189-360:622) DRAP deaminase n=4 Tax=Saccharomycetaceae RepID=A5E2D2_LODEL   E=9e-41 s/c=0.98 id=28% cov=65%
-IKIVYQDDDLLVIDKPSGIPAHPSGRYRYNSVT--KILQHEMGIVLHPCNRLDRLTSGLMFLGKTAKGSTKLMTQIKDRNVSKEYIARVKGKFPKESITVDQPLLTLNPRLTLNVVDFVKGKEASTEFKRISY---------DPKTNTSVIKCHPLTGRTHQIRVHLQYIGYPIANDPIY-------------------------------------------------------------------------------
>UniRef50_C8PSH6(12-236:240) Pseudouridine synthase n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PSH6_9SPIO  E=1e-40 s/c=0.75 id=32% cov=82%
-LDILYEDPSLIVINKPSGLLSVPyqGSSVRTAADILERIMRSKGAyskhHRPFAVHRLDRDTSGVMLFALNERTKDEFMRSWHTLVTERIYRAVaenpAEGGLADSGIIDAPLAYNAYNRAFVPTAEKHahfDTVAARTRYKIIER-----------GAAYTLFELSLDTGKKNQIRAHLAANGYPIAGDPI-GHARTDPFG-------RLALHARSLAFTHPVTRKVMRFEVPEPEAWLAYI-----------------------------
>UniRef50_B2GFH2(102-313:326) Putative pseudouridine synthase n=1 Tax=Kocuria rhizophila DC2201 RepID=B2GFH2_KOCRD  E=1e-40 s/c=0.79 id=30% cov=82%
-LDVLHEDEWIMAVDKPHGLCSTPKGENVRRSVVVAARCQ-FDNDEISALHRLDRSTGGVLLLCKRAEDRSAFHRLFQERTVRKTYWAVA-GVNERVGEQTVRVESRIRKIQGVVQAfEEPGEVNAVTDVRRVETFT-------DADGTWGLYEIAPLTGRTHQIRVHMTSLGLPLRGDKLYPQPRQDFDVEDPE--NPLQLIARSIEFVHPVTGRAVRIDSRL-------------------------------------
>UniRef50_C9L5B3(30-234:244) Pseudouridine synthase, RluA family n=1 Tax=Blautia hansenii DSM 20583 RepID=C9L5B3_RUMHA  E=2e-40 s/c=0.82 id=29% cov=78%
---VLYEDKYILVCQKPAGFPVQSKRLGTLDMECALRNYLAKKGQEPYvaVIHRLDQPVQGVLVFAKDKESAAKLSKQMQQGKFEKTYLAYTQGHTDKKQeTLIDELEKDGRTNTSKVVaKKTANSKRAELSYKVLKETEEG-----------SLLEVSLKTGRHHQIRVQLAHAGLPIFGDAKY-----NVKCTKEDANHGVSLCAYKLSFLHPAKGKKMEFQ----------------------------------------
>UniRef50_C4XN86(119-308:339) Pseudouridine synthase n=2 Tax=Desulfovibrio RepID=C4XN86_DESMR   E=2e-40 s/c=0.88 id=31% cov=72%
-LEILHEDDELLVVVKPAGLPVHPGSGHTFALTTLLHAHAPHAPFKPTPAHRLDRDTTGLLLVAKSYRRLRALHEAMQDGTLRKDYFAWVWGKWllgeeNEWVTMRDALAKSGGPGRER-VTAGEDGKEAVAKVRLISRAPT-----------ASLVEVRLETGRTHQIRAQLASRGYPLVGDAKYGG-----------GPTPLRLHAWRVILP---------------------------------------------------
>UniRef50_C3XV24(72-329:335) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3XV24_BRAFL  E=2e-40 s/c=0.65 id=32% cov=82%
----LYDEGDIVAIEKPYGVPVHGGPGmGVSIADSLPLLQQALKTDRLYLVHRLDKETTGVMLLAKTDDMARQLHSLFRLRKVIKKYWVLTMGVPSHeEGVVDIPIKElevtaqgrphhrmvcvpeysEETKLIVKKKRKSSDAQIAITNFRVLDS-----------CGSCALVECQPETGVKHQIRSHLSYgLGCPILGDHKYSHHSKLAPQRlptgmlERFGIQqpkarylPMHLHARQIVLPGFRDGRSLYFTARLPDFF---------------------------------
>UniRef50_C0R003(18-234:241) Pseudouridine synthase n=2 Tax=Brachyspira RepID=C0R003_BRAHW   E=2e-40 s/c=0.77 id=26% cov=81%
----IYEDNHIIVAVKPPNIPTQGDitgdvSFFENIKDYIKIKYNKKGNVFLGLVHRLDRPVSGIIVFAKTSKAASRLSEAIRDRKFEKTYYAVVNGIlLEKEAKLENYLIKKTNKLGNIAQVVFENTKNAK-----IAKLKYNVIKEDVI-KNLSLLRIELETGRFHQIRVQLANIGHVIYGDRKYGSY-----IKYDRNDVPLALFAKSLRFPHPTRDEEIYVEADLP------------------------------------
>UniRef50_C0QPR0(73-265:272) Pseudouridine synthase n=4 Tax=Hydrogenothermaceae RepID=C0QPR0_PERMH  E=3e-40 s/c=0.87 id=30% cov=74%
---VIYEDQFILAVQKPPFLESEGRKG------SVEYQLRKVLDRRLKAIHRLDRETSGVLLFAKNEKIFHRFKDLWHRKEVVKVYLSISYG---------------EAKFKKKVVNMPVDKKYAKSIF-----------FTKKISKGFTLFEVEIKTGRKHQIRIHSSKIRHPIVGDKIYGLKKVEDPLTKN--VKRQMLHGYRLRFLHPFTGKVVDIKAPVYHDFYN-------------------------------
>UniRef50_C1E9U3(213-540:545) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E9U3_9CHLO   E=5e-40 s/c=0.51 id=27% cov=90%
-LDVIHEDDDVLVVNKPPGLRFHPVHRFEGNSLLSRAIGHvrrsgrdddrldgdaagDGHAHVPHVVHRLDMDTSGVCVLVKRPELVDGFARQFRgdagERRAVKEYLAIGVGAAPPgvtgcvvkadwkppeasgneqttaaefigvEFTVDAHVGphasipearavhRPPPTPERIPKRNGSGGdpdapKPARTDVRIVSSSRVPIDVNDDGDVMQSltavLARVRLHTGRTHQIRVHMAHADLPILSDPLYGPHIRWDGASPcadastsailppgvdadvwggPRWLGRQALHAARLTLRHPETNEEMTFEARAPEDMRGACVALG-------------------------
>UniRef50_C1N7S8(37-318:360) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N7S8_9CHLO  E=5e-40 s/c=0.59 id=28% cov=94%
-LTVLYEDEHVLAVDKPPGVMTYPAHRLRGGSVVNraVHHLRgvtrdgsgggagfgFGAATEPIAVHRLDLETSGVLMLAKDKPSASALQGAFERREARKTYLAVCailedaanasDESDDDFDFERHPGHRRRERRRRAVHTRGDAGREAREH-----------RFTGKRIVGTALVLARPLTGRTHQVRLHLAHAGLPIVGDALYGYDDALRPASGGFE-GRMALHAWNLAVKHPRTKNTMRLAVDMPADMQALSVGLGLRvegvllgdaaaaaAAAGAAKRTSTSARTGSDG----
>UniRef50_B5JG19(19-244:262) RNA pseudouridine synthase family n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JG19_9BACT  E=8e-40 s/c=0.73 id=32% cov=75%
---ILQNDDHVLLINKPALLVCHPSKNGPWSSLAGA-CREYLQSERSHLVSRLDRETSGIVLFAKHRLKSRHLQMALEQRKVSKTYLAILEGELKEETLVDAPLGPDTQSIVhsKNTVRRDGRKQEAQTKYTPL-----------HSNGRYTLAKVDPITGRKHQIRAHALHIGHHIVGDKLYGPDEglfldfiedgWTEQMAKILPINRHALHAYRMVF----------------------------------------------------
>UniRef50_B3E6K8(78-299:300) Pseudouridine synthase n=1 Tax=Geobacter lovleyi SZ RepID=B3E6K8_GEOLS  E=8e-40 s/c=0.75 id=30% cov=81%
-IDLLWQDDRLLAINKPAGLAMHPAAEVDENLADIAsawLEKKANYPVRAYPVNRLDRGTSGVVLLATSSSNAGILGRQVKEEGLDKIYLTVVEGMLEGIGEISQPL----------------DGKESISRYRSLSVGES-----------CSFLLVEPVTGRTHQIRRHLSAIGHPVLGDKRY-------DAQPLATLPGIALHSFRTRLQHPTPETRLTLCAPLPTALRELiIERCG----IDEKELLDL------------
>UniRef50_Q25257(511-735:741) ORF C n=5 Tax=Leishmania RepID=Q25257_LEIDO   E=9e-40 s/c=0.74 id=33% cov=80%
IIPVLYEDDDVLVVDKPAGLATSRHGlsctqlGTPTTDLISVLLATDRVGAlargifRQGQVHRLDAETSGCLLIAKSDVAADSLRHQlgtsaaFSHH--SKIYHALCVV-----------LEPSLRNVRLHDDIIDAADPKIRTRYRVIR---------FFPKHRVAWVECRIQQGKKHQIRRHLASRGLPILADLEHGGAVCCQSM-----ISRVALHAHSLSFIHPVTADPITAAAPLPADFRRCLSLL--------------------------
>UniRef50_A1KW96(20-219:236) Pseudouridine synthase n=9 Tax=Neisseria RepID=A1KW96_NEIMF   E=9e-40 s/c=0.82 id=31% cov=77%
MLEILFRHQDFVAINKPGGISVHQDSGETGLARTLAIQL---GVERVWLLHRLDKQTSGILLFALNRESASALSGQFAGKSIKKTYLALSDRKPSKKQGWIKGGMEKSRRGMWKLTRNTENI--AVTRFHSISIAE-----------KLRLFILEPHTGKTHQLRVAMKSLGSPILGDSLYGGTESET----------MFLYAWKIQFA--YQNRQIEIVAPLKNEWQ--------------------------------
>UniRef50_B7FU02(1-239:240) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FU02_PHATR  E=1e-39 s/c=0.69 id=33% cov=85%
-LHILYCDEHICVVNKPSGILSVPGPrRNPSIANLVYEILNPPIDIDQMVVHRIDMDTSGVLVFALTELALRQLHDDFRSRRVKKTYEALLAGHFRKATQVEIDVALERDPYHPPFMRRYWEPQRSATYSRQFSQIYQPSAQAHLP---VSRVHMSPHTGRTHQLRVHAAALGYPIIGDDIYGFEGEGDCGVNSTILDQLipnrmslhqqlqelqlplCLHAKQLCIFHPFSGAPMIFECEAP------------------------------------
>UniRef50_A8RLV7(1-243:274) Putative uncharacterized protein n=4 Tax=Clostridiales RepID=A8RLV7_9CLOT  E=2e-39 s/c=0.67 id=27% cov=83%
MVPILYEDKDIIVVQKPAGLESQVSRGFAPDMVSEIRRYLHNPqdihnhpqgvstaqPPYVGVIHRLDKPVEGIMVYALNQKSAASLSAALQAGKIKKSYLAVVCGKPvDKQGTYVDYLRHCKENNTSKIVdKSDENSKKAVLNYRVLEVINNPKNQEQI----LSLIDIELLTGRHHQIRVQFAGHATPLYGDERYGGGLSTKSTTMTVDRGRkkssfgdahrpLALCARRLAFPHPSTGKIMEF-----------------------------------------
>UniRef50_C2KWN7(91-337:340) Pseudouridine synthase n=1 Tax=Oribacterium sinus F0268 RepID=C2KWN7_9FIRM  E=3e-39 s/c=0.66 id=28% cov=85%
---ILYEDKHCILFNKPVGLLSENDGSSSFSVNSLLLSYMRTKGElskeqeksfRPGIANRLDRNTSGIIIFGKSLGGLQAFAKLLQSHDLEKKYYALVYGDFQKTGMQEHFLEKDKGQNK---ALESERGKRVKSAFEKLACVESSVGSLSLLSV-------QIFTGKTHQIRTQLSLLSHPIVGDDKYGDTRKNARLRKTLPLSYQLLHAYSLRFPkLPessvlFSLSEKCFFAPLPKEYFEILKSF--------------------------
>UniRef50_B8BQ07(21-243:246) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BQ07_THAPS  E=6e-39 s/c=0.73 id=28% cov=80%
-IRVLYSDDDIVVIDKPANLRSVP--GHASNSPDADDGSKSKY--QLHVVHRLDCQTSGIMVVARNSTAASKLCHAWRERDiVQKTYLAYCQRWPPYhdeqlsEGTIDLPLAASRTERIKWEVRAlEDGGKPLKSELTV-----------ERDNDNGVVLELKPITGRTHQLRIHCATIGSGIVGDSLYGDSPVEWFGDKpqhgqqtisQSDTQTLRLHAHKLVFPHPSTGSEVTFVSP--------------------------------------
>UniRef50_D0KW62(23-221:222) Pseudouridine synthase n=1 Tax=Halothiobacillus neapolitanus c2 RepID=D0KW62_HALNC  E=4e-38 s/c=0.80 id=29% cov=77%
----LAETADFLIIAKPTRMLTQPGKEAHKTDSLITRV--NQEFPEARIVHRLDWDTSGVMVLARHARAHRALSIAFQDRRTKKCYIAHVDRAPaPPQGLIDRPIGSDREH-RPRYRIDEEQGRPSQTRYVVL-----------NETADFARLALEPITGRSHQLRVHLLSIGHPIQGDTLYHPHAQNHA--------RLMLHAESLSFPDPASGITQTFSDPVP------------------------------------
>UniRef50_Q7UWB9(19-231:232) Pseudouridine synthase n=1 Tax=Rhodopirellula baltica RepID=Q7UWB9_RHOBA  E=6e-38 s/c=0.75 id=33% cov=78%
MIEILWQCHACVVVNKPVGLPTT-SPKGTDSLESCLREQFAQAGnpvSYLTAVHRLDRPVSGLVLIALRKKAARLLSEQFRLRHVQKKYIAMVQGNaleaCKQEPWHDTIAKLTDEARVEIVGLDSTDGRQAETKVSFLEY---------DSESDTSRIELRPVTGRMHQLRIQSAHRGHPIVGDPLYGTAEDESA---------LRLVAAKLSFRDPTNGRAVEVELP--------------------------------------
>UniRef50_A4A0R6(27-242:242) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Blastopirellula marina DSM 3645 RepID=A4A0R6_9PLAN  E=8e-38 s/c=0.74 id=26% cov=82%
---VLYEDNHLLAISKPALLATMGAQEGEPSAAqwakdYLKRTYNKPGNVYVGIVSRIDAHVTGVLLFARTSKAASRLSEQFRDRSTVKEYAALIPAGPKIRNGELVDWIRKEDRLHRMVIAAEGTADADRAEMEILEQQRRP---------NCQMLHLRLITGRKHQIRLQLASRGAPILGDKKYGSTDRYS--------PGIALHAHRLVFTHPTLKTMVTIEAPLPEAWRPYL-----------------------------
>UniRef50_A7ZDY2(60-245:252) Pseudouridine synthase n=4 Tax=Epsilonproteobacteria RepID=A7ZDY2_CAMC1  E=1e-37 s/c=0.85 id=35% cov=70%
---VIFEDENLIAINKPAAI-----------TSEKISQIYKFP-----LLHRLDKDTSGVLLLVKNDEFASLAINEFKKMKVEKIYVAAVRGIMSEEVVVNEPILTIKNKNG-AFSKISKDGKEAISEISPLMVV-----------GKKTLVKVVIKTGRTHQIRVHLASLNLPIVGDEKYGKNRAN----------RMFLHAYSIALLD------YKFKAPIPREF---------------------------------
>UniRef50_A6LT86(82-314:324) Pseudouridine synthase, RluA family n=35 Tax=Clostridium RepID=A6LT86_CLOB8  E=2e-37 s/c=0.68 id=29% cov=76%
-IKIAYEDENVVVIEKWPDVLVHSDSNNSEEptlTDYVLSYLNDKGDyipeneitFTPAACNRLDRNTSGMVMFGKTFEGLKAINEAIREDEIRKYYYALAKGKI-RAGLYEAYILKNPETNTSKIYD---------TEVKNSKKISMEISI-VESNGAYSLLEIHLITGRSHQIRAHLAHLGNPIIGDNKYGDKKLNSFFESKYGLNFQYLYAYKLNFR---------------------------------------------------
>UniRef50_C8PJZ2(77-462:495) Pseudouridine synthase n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PJZ2_9PROT  E=4e-37 s/c=0.41 id=30% cov=85%
-VEILYEDDDLLVVNKPAGLTVHPAASVKEPTLVDWlksrgYLLSTLGGElRAGIVHRLDKLTSGALLVAKNNAAHAALSAQLSDKSMGRIYLALIDLPLKEPCVIERPISRNPANRLKMGIV--PGGRSAKSAFyeilsgaeltelqnsaercdeilgagdgtaanasasristeekilgdamdkistgdankisavstgkdkilnasrdadasKILAThasanpnagtdkilnnradnvdeisnncmqsadkiliqsadkipnnradnadkiltadmsadqtqtarlaenkalnFKNPAQNYKLPPINlksFNLVAAKLFTGRTHQIRVHLSSINRHILGDHLYGFKSENAK------ISRILLHAYLLYFIHPRSGKEVKICAGLPSEFLN-------------------------------
>UniRef50_C5DCE4(114-309:397) KLTH0B02376p n=2 Tax=Saccharomycetaceae RepID=C5DCE4_LACTC   E=5e-37 s/c=0.80 id=31% cov=64%
---VVHECEDLLVIDKPSGIPIHPTGQYYQNTLV---EVLKSHGKTVFPSHRLDKITSGVLILTKNPHMANKIQHQIRQRTMSKIYLARVDGAFPMadtlgsltpfespDKTQTVDSAIYTVELKKQFPAAFSPPREAKTKFYPLKY---------YPKSDETLVACQPITGRTHQIRIHLARLGHPIVNDPFY-------------------------------------------------------------------------------
>UniRef50_C3XID6(80-300:326) Pseudouridine synthase n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XID6_9HELI  E=5e-37 s/c=0.71 id=17% cov=82%
-IEVIHENSDYLILNKPRNLVVHHAPSVKEVTLTDYLSAKNYelstinGEMRFGIVHRLDKDTSGAILVAKNNASHLRFAEMLQNRTMGRIYICVINKALQHNTFVECYMGRNPNNRLKMAKLDKEKypfARDSKSEFRKI---------MESKNGVFELIGVRLFSGRTHQIRVHLSTLQRYIYGDMLYSPENLKSTYKTK-----MLLHAQLLYF----DGN--VFSAKIPKDLLKFLNE---------------------------
>UniRef50_A9RZN1(1-268:283) Predicted protein (Fragment) n=1 Tax=Physcomitrella patens subsp. patens RepID=A9RZN1_PHYPA  E=8e-37 s/c=0.58 id=31% cov=65%
------QDAEIIVINKPSGLAVQGGSDVVKSLDSMMEaALSYNYNEGPRLVHRLDKETSGALVLGRTHQSTVFLQALLRNKTekisqaPGRCYLALVIGVPeKKEGRISAPLAKvvsDSGKLDKMRVVHgsHPNAQEAITDYKVL---------GSSLFAGCSWLELRPLTGRKHQIRVHCAEvLGMPIVGDYKYG------------------------------------------------------------------------------
>UniRef50_Q7XA65(76-316:322) RNA pseudourine synthase 1 n=12 Tax=Magnoliophyta RepID=PUS1_ARATH   E=1e-36 s/c=0.64 id=29% cov=82%
--DILYEDEYLMAVNKPKGVYC-------EAVLRSAPQIVLDSSSEYHLANRLDRDTSGVMIITKSHKVAAKLVKAFTEHKIRKSYIALCIGsSPNWRRVTVSSGHGRSKHGAWRVYaaldvgRVLPGGsfvRDMETTFEVVSVNSVKNESCELEDVNHVIVaegerelscggddddvvvvvRAFPRSGRTHQIRLHCQYLGIPIRGDVKYHGVYEWNGRT----FEGHELHAECLSLDHPVTGDSIVIRAPLP------------------------------------
>UniRef50_C0W298(129-357:358) Pseudouridine synthase n=1 Tax=Actinomyces coleocanis DSM 15436 RepID=C0W298_9ACTO  E=2e-36 s/c=0.67 id=26% cov=82%
-IPIVHRGNGWLVINKPKDIASTPRGSYIVRTATIA-LRRQEGNADLTPAHRLDRATSGLLLFTERPELRGMYQDLFQNRQVTKTYRATAKAIdfnyikssalvkitvdPEEQPGWVKIESRIEKRPGDPGAQHAFGKINAVTYLRPVKTVTI-------EGQQFVEYEVQPQTGKTHQIRLHFASLGAPLVGDPLYGGFNAAPFGLEKVPAGYQELHleACRLEFKDPQTQEMVKIE----------------------------------------
>UniRef50_Q57Z98(600-825:828) Putative uncharacterized protein n=3 Tax=Trypanosoma RepID=Q57Z98_9TRYP  E=2e-36 s/c=0.68 id=35% cov=80%
IFPVVYEDDDLLVINKPPHVATSRHALscsqlcdDKATDIVSLQLTCKKRGDvmrrvfRQGQVHRLDTETSGCLIMAKSDVAASSLRHQMgtsaAYSQSSKIYLALC--AVVESNLTNIPLNGVLRDPADAKIT---------TKYRIV---------HFYKRFRVALVEARIQQGKKHQIRRHLAAVGLPILQDVEHGGAACC-----SPLLQRVALHASSVTVVHPRTAEVLTCVAPLPEDMRSAI-----------------------------
>UniRef50_D1SY25(116-317:328) Pseudouridine synthase n=1 Tax=Acidovorax avenae subsp. avenae ATCC 19860 RepID=D1SY25_9BURK  E=3e-36 s/c=0.76 id=26% cov=78%
---VLYQDEHLVVADKPHFLPVVPTGRYLQHTLLVRLKRRLGLD-GLSPVHRIDRDTAGLVLFSVQRATRGRYQALFRDRAVDKTYEAVAP-WRVDVAFPRERSSRIEESPQFFRMHEVPGEANSLTRMEVLDV-----------DGAWARYRLSPVTGRRHQLRVHMAALGLPLRGDAFYPEVNDPPEGDFSRPLQ---LLARAIAFTDPVTGRERRFES---------------------------------------
>UniRef50_C7H0C0(83-273:322) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7H0C0_9FIRM  E=1e-35 s/c=0.80 id=25% cov=68%
-FKIIFEDDNLLVVYKRAGLLTHGSSTEKKRTLLNevkTYLIQKGEYDPgfektfsLATSNRLDRNTEGLIAIAKNAASQRELNAAFKEGRIERYYVAEVVGEVRGDVTIDYPLYKSAKNNTvfadKDGSVPPDVTKEAITKVHPIRVNRIDKNGSEFT---YTVVRVKLLTGRTHQIRVHLAAIGHPLVNDRKY-------------------------------------------------------------------------------
>UniRef50_Q7VI73(69-289:303) Pseudouridine synthase n=1 Tax=Helicobacter hepaticus RepID=Q7VI73_HELHP  E=2e-35 s/c=0.68 id=30% cov=66%
-LEPLFFNEDFCVYDKPHNLLTHPKGRFYHYSLNDALKLR--FGNYANAIHRLDKQTSGLVLCAINPQSEPELKELISTRQILKTYYAIVEGKLTQECLIDEPIAlqKYKGTDLSIKSIISPYGKPSRTKLYPLAY---------HSPTDSTLIRVLPLTGRTHQIRLHCAHIGHRILGDPLYG------------------------------------------------------------------------------
>UniRef50_A8SPE4(90-330:334) Pseudouridine synthase n=2 Tax=Clostridiales RepID=A8SPE4_9FIRM   E=2e-35 s/c=0.63 id=29% cov=78%
--EIIYHDHNVLIVNKPVGVLSQKASKDDYSiNESVLDYLLDNGYItseqlrtyKPSICNRLDRNTSGLVLCGVSLMGNQELSRIIRERNIDKYYYTIVKGHIKSVQDVTAYLVKDEKKNTVIVRDgVDEIKQDSgKNEFEKIHTIFEPVR----SNGKYTEVKVKLITGKTHQIRAQLSHMGYPIVGDQKYGDRETNIYFRQTYKLRNQLLHCGEVKFT---------------------------------------------------
>UniRef50_C4Z1D5(1-219:225) Pseudouridine synthase n=1 Tax=Eubacterium eligens ATCC 27750 RepID=C4Z1D5_EUBE2  E=5e-35 s/c=0.68 id=24% cov=77%
MLNIIHETKDIIIVNKPAGQLSQGAKGFDLDlvSEVMTYNASQGKPAYAAIINRLDRPVSGLVLIAKNKSAAAKYSTLMqKEGGFNKQYEALICGKLsESKGTFVDYLKKDGRTNTSAIVPadaaaNDKEAKLSKLEYEVISYDEV---------KDITHVRIHLITGRHHQIRVQFASRRHPLVGDYKYATADcgmDNAVKAVAFKRNQIALCAVSLTI----------------------------------------------------
>UniRef50_B4RU15(4-235:279) tRNA pseudouridine synthase A n=2 Tax=Alteromonas macleodii RepID=B4RU15_ALTMD  E=7e-35 s/c=0.64 id=29% cov=77%
-IPILFEDANLLVVNKPVGVAMHDAldskSGDPKDNALAIEHedtdknaaqkessackgedtlrtdgivtqLKKQLSlSELHLCHRLDTGTSGCLCLAKNAKTAAEIGELFSSRRIGKFYLALSEHKPKKKQGAIIGDMKNRRGGQRILLKSQEN--PAITQF---------FSHAAKPGTRGFIV--KPHSGKTHQIRVALKSIGAPILGDSLYGGAPS----------DRLYLHAWHLRL--PLSAGELTITAPFD------------------------------------
>UniRef50_UPI0001BC98D7(117-324:324) RNA pseudouridine synthase family protein n=1 Tax=Pseudomonas syringae pv. tabaci ATCC 11528 RepID=UPI0001BC98D7  E=9e-35 s/c=0.72 id=26% cov=80%
---ILYADEHLVVADKPHFLPVTPAGEYVEQTL-LRRLIHRLGNPDLVPLHRIDRHTAGLVLFSANRQTRSAYQALFPTRQIDKFYEAIAP-ALPGLEFPRLHESRLVEGEPFFRMQEGAGASNTRTQIEVLERQDQLWRYG-----------LYPVTGKKHQLRVHMAALGAGICNDPFYPDVVKNPVDDYQNPLK---LLAKGLRFIDPLNGKQRQFESLLELDW---------------------------------
>UniRef50_Q6CG33(109-326:337) YALI0B01276p n=1 Tax=Yarrowia lipolytica RepID=Q6CG33_YARLI   E=3e-34 s/c=0.67 id=30% cov=63%
-IRIVFENDALVVVDKPGGIPVHPTGKYLFNS-VKEILKHETGLEELYPAHRLDKNTTGVLVFAKTSESVNHVTQQIMSRSAKKEYLARVKGRFPPGRVETHH------PVVENTIKRNVQPKDAHTAFERVAYDEHR---------DLSIVRCLPSTGRNHQIRQHLLHLGYPIENDREY-------------------------------------------------------------------------------
>UniRef50_B9W8E1(110-299:405) Hydrolase, putative (Drap deaminase, putative) n=5 Tax=Candida RepID=B9W8E1_CANDC  E=4e-34 s/c=0.77 id=24% cov=72%
----IYEDNEILVVDKPSGIPTHPTGNYYHNSLSEIIKQQYNMDS-IWTCHRLDKVTSGVLVLAKTKNGGVKFSKLMRDskQHTKKTYLARVSGKFPEGiHQYRCPIFAVNMNGYLMSGNMEELPTDSTTVFEQIKY---------NACLDQSLIKCIPITGKFHQIRIHLRNLGFPIVNDSFYqPDKQKNQLTLQKCNIERQL------------------------------------------------------------
>UniRef50_C1MIE2(196-542:547) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MIE2_9CHLO  E=6e-34 s/c=0.42 id=27% cov=88%
-LEVIHEDDAILVVNKPPGLRFHPVHRFEGNSLLsrcighirrrrrrrrrasddggedggedadadgeekVDDDEDAHADDMPHIVHRLDMDTSGVCVFVKDKSLVDGFARQFRGDDagVKKEYVALAVGTVPrgdvvafsseaeevrdddddaaaaaaaaavgRAFVVDAHIGDHATMPEARAVHPPPlvasttratdpsadasAPKPATTACVV------SSSAAARDGLVAALVRCAPRTGRTHQIRLHLALANLPILSDPLYGPHVRFGGAAMaenargkaggeeedgggggdrgyfaaelegywggDLWLGRQALHAASLTVRHPKTDVSMTFRAPLPEDMRRACVALG-------------------------
>UniRef50_D0LDE5(93-291:317) Pseudouridine synthase n=18 Tax=Actinomycetales RepID=D0LDE5_GORB4   E=1e-33 s/c=0.73 id=34% cov=75%
-LPILYADENIVVVDKPHFLATMPRGRHVTETALV-RLRRQLGSDDVAPAHRLDRLTAGVLLFTLRREVRAAYQDLFATRAATKEYRALapVDDALTTTVTIRNRIEKTAGDLRARVV---DGPVNAISDITLLS--------------DAGLYRLVPHTGRTHQLRLHMASLRVPIVDDPLYPDVRPELAQRPDVGdfSAPLRLVAHALEFTDPFTG----------------------------------------------
>UniRef50_A1WL43(104-305:314) Pseudouridine synthase n=12 Tax=Proteobacteria RepID=A1WL43_VEREI   E=1e-33 s/c=0.72 id=27% cov=78%
----LHQDPHLVVADKPHFMPVTPSGRYLQHTLLV-RLKRQLGLPQLSPVHRIDRDTAGLVLLSVQQCTRGAYQALFRERRITKHYEAIAP-WRADVVFPRDHTSRIEPGPQFFRMQEVPGPPNSHTHMQLLAVA-----------GDWAHYRLSPSTGKRHQLRVHMAALGLPLRNDPFYPVVDDPPPGDYSRPLQ---LLARALEFVDPLSGERRVFES---------------------------------------
>UniRef50_Q6NEJ6(129-344:349) Pseudouridine synthase n=6 Tax=Corynebacterium RepID=Q6NEJ6_CORDI   E=2e-33 s/c=0.67 id=22% cov=81%
---VVYEDDTLLVADKPPFLATMPRGKHITNSATV-QLRRSTGIDELSPAHRLDRLTSGLLLFTKRKRVRGAYQTLFSERNVRKTYVATAQYNPsiTPGTIWRSHMTKTAGEIQGHIIDAPPN---AETLVSAIERIDAPTQQHLHAlhgtDVDLAHYTLKPHTGKTHQLRLHMLAAGVPILGDTIYPTILAEDAEDYSRP---MHLTSTELEFIDPLTGRPRLFT----------------------------------------
>UniRef50_Q6A5E7(78-289:295) Pseudouridine synthase n=4 Tax=Actinomycetales RepID=Q6A5E7_PROAC   E=2e-33 s/c=0.68 id=32% cov=79%
---ILYSDERILVVDKPHFLSSIPRGRHVLESVVVRLRTQLGL-PELTVAHRLDRVTAGVLLLTRERKWRRPYQEIFERREVVKKYrlVAPVVHDPAGEGVTATKSGWQVRSRIIKergilQAREVPGVPNAVTDIALIGE-----------HGGWGLYEASPRTGRTHQIRLHMQRLGAPIVNDPFYPVVLDTPVDDFTHPLQ---LQAWRMGFTDPVTGDPRAFTSRL-------------------------------------
>UniRef50_D2Q929(36-257:264) Ribosomal large subunit pseudouridine synthase D n=19 Tax=Bifidobacterium RepID=D2Q929_9BIFI  E=2e-33 s/c=0.65 id=25% cov=82%
--EVLYEDDGIIVIDKPHFLATTPRGMWYRETA-LIRLRERYGEPDIVPAHRLDRLTAGVVVFVRKPELRGAYQMLFQEHRTVKTYECLAPLAPvvrprygtvtRIDRNQPFPLVRRSHIAKDRGRLQAYEIPAAVNAESLIERGDNPRIIDGNVVINYVL---HPKTGKTHQLRVHMNSLGLPILGDVFYPDVIQRPYDDFSRPLE---LVARRLEFDDPVTGESRAFVS---------------------------------------
>UniRef50_Q6MN39(1-205:225) Putative pseudouridine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MN39_BDEBA  E=3e-33 s/c=0.70 id=25% cov=77%
MIQIVFENTHFIICDKPAGVLSTPSRFEEDDaRLCLGTALQKEKGFQIFPVNRLDFEVSGLVVYAKTAEAHRKANAWFEHKTVKKTYRALTTGqsyahIPANVPNEKLKLTPEVGNTFEWRCRLLRGKRRA--YESPQGKECLTVAVFRGMQGDYQVWDLNPVTGRSHQLRFDLSRHGFPIVGDKLYG-------STVELADNRIALRSYRIDF----------------------------------------------------
>UniRef50_C7R188(132-344:362) Pseudouridine synthase n=3 Tax=Actinomycetales RepID=C7R188_JONDD   E=6e-33 s/c=0.67 id=27% cov=82%
--DVLFEDDDLYVIDKPHFLASTPKGRYVTETALV-RLRKDTGNPELSPAHRLDRLTAGVLVFTKRRELRGAYQELFAQRQVTKVYQAVAPTNPAVDlpATVRSRIVKEHGIMRAHTMPGEPNTETLVT----LTDTATLPAGHDVAVQDVGLYTLYPHTGKTHQLRIHMASLGLGIVYDNYYPDFYHVESDDYRHPLQ---LLSSQLAFTDPLSGVQRDFRS---------------------------------------
>UniRef50_Q31G00(8-210:238) Pseudouridine synthase n=6 Tax=Gammaproteobacteria RepID=Q31G00_THICR  E=7e-33 s/c=0.70 id=28% cov=73%
-ITVVFQSTEFIVVDKPAGMNFHsePDSDGQKQPGLVVFVQQQLGVEELYPVHRLDKMTSGLVIFALSKASAKAFQQLFESRQIQKFYLAISTHKPKKKQGWVKGDMMPARRGSWKLSKTLEN--PAITQF---------ISQNTRPGERWFLL--NPHTGKTHQLRVALKSLGAPIAGDARY------ALSAEAEHEDRGYLHAFALRFT---------------------------------------------------
>UniRef50_A0KLM3(1-201:219) Pseudouridine synthase n=2 Tax=Aeromonas RepID=A0KLM3_AERHH   E=1e-32 s/c=0.71 id=26% cov=77%
MYRILAQHKDFMVINKGPGLGMH-DETDEAGLLHpgLVSRVKADTGLLLYPVHRLDKMTSGLVLLARTTEANRALSMAFAAREVSKQYLALSDRKPKKKQGWVKGDMQKGRGGSWMLTRTLDN--PAISWFDSVSVRE-----------GLRLYRIKPRTGKTHQIRVALKSVGAPILGDARYGGTA----------ADRGYLHAWRLAFT--LAGEAFDFVCPPDE-----------------------------------
>UniRef50_B6K9V8(1910-2166:2780) RNA pseudouridylate synthase domain-containing protein n=3 Tax=Toxoplasma gondii RepID=B6K9V8_TOXGO  E=1e-32 s/c=0.55 id=26% cov=88%
--DVLWEGDGLTVIDKPPGWhcsdvrydpqtesrqlccIVSSSRPEPLGLYCSLRFNYPTGKLKecnFGLGHRLDVDTSGPIIIAQTLEAWQWIRDQMHKRNISKEYICLCHGTLaEGFHVIDSPIITSTDGRRLQSYIHHA-GQPSLTVVKPLAHLEHRELRYPGSTTplQFTLNWVKIHTGRTHQIRVHLQSLLdsrgrpHCLVSDDKYGNGQQVEDFQ---WCRRLFLHQHRLSFRD-LNDTPQCFVSPLRADLLSALRHL--------------------------
>UniRef50_A4CVN5(20-213:215) Pseudouridine synthase n=1 Tax=Synechococcus sp. WH 7805 RepID=A4CVN5_SYNPV  E=2e-32 s/c=0.73 id=31% cov=73%
----------LMVVDKPAGLLCQPGlGSHQQDSLISRLQLAC---PALRLVHRLDRDTSGLVLLAKDPDMLRLLGMFFASRRVRKLYVADVQGQMKNvSGLIGLPLARL--KRQPPTYGVHPGGKACVTLWRRLKLMESS-----------TRLWLCPRTGRSHQLRAHLAALHHPIIGDPIYNPGCAV----------GLRLRAMALRFPDPDdpSGQ-VRVRAPWPAWF---------------------------------
>UniRef50_B8J0V1(122-306:360) Pseudouridine synthase n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 RepID=B8J0V1_DESDA  E=2e-32 s/c=0.76 id=27% cov=64%
---------YLWAFDKPAGLPVHPGTGHEDSLTTRLSCHFAGVSFMPTPVHRLDRGTSGIILVAASYAALDETQRALRANAMHKEYVAWVAGRWPHTQTClvRHFLRKEAVDGFERVRPVKADAPDA--------KEALCLVRALSIADRASLVQVRLLTGRTHQIRVQLSSLGHPVLGDTKYG------------------------------------------------------------------------------
>UniRef50_D0BPC6(90-288:304) Pseudouridine synthase n=7 Tax=Fusobacterium RepID=D0BPC6_9FUSO   E=2e-32 s/c=0.71 id=26% cov=65%
---IVFENDNLFVINKPLGDVVHKGSGHDISLLEEFRSY--YSNNNINFVNRIDKLTSGLVIGAKNIKTAREVAKEIQAGNIVKKYYILVNGKIEKDNFILENYLKKDEERVIVSDIEKEGYKKSITYFKKIKEYD-----------KYTLLEAELKTGRTHQLRAQLNHLGNNIVGDIKYGK-----------------------------------------------------------------------------
>UniRef50_UPI0001792C80(31-253:278) PREDICTED: similar to RNA pseudouridylate synthase domain containing 1 n=1 Tax=Acyrthosiphon pisum RepID=UPI0001792C80  E=3e-32 s/c=0.63 id=27% cov=75%
-VEIVYKSNDFIIVNKPEDVFTNNHNKARPSLDVLLrkkypHLVNSNLEHSFYFVHRLDFVTSGVLCIALNKRACAKASCAMQKRISRKYYIALVRGHVSQDHLDltdsIGYCAREAEGNRKMCTIDKvccTGPRDAHTRLVVLER-------GVFMSYPATKVLLQLITGRRHQIRVHCSTIGHTIVGDYTYSGRKDISP-------SRTFLHSYRLEL----------------------------------------------------
>UniRef50_C7LWX3(89-268:306) Pseudouridine synthase n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LWX3_DESBD  E=4e-32 s/c=0.78 id=25% cov=69%
----VFENDEMLVIDKLAGLPVHGGTGWTDSVHDRLKACFAGQAFVPIPVHRLDRDTSGLLLCAKTHDFLRAMHASWP--TLTKGYLCWVEGAWAAAGWRTVVSELAKAQTGSGEQVVSGQGKRAVSHVHPV-----------LVTAGKSLLLVVLGTGRTHQIRVHLADCGHAIVGDPRYGQGG------------GLLLHAAALS-----------------------------------------------------
>UniRef50_A9RVX3(69-264:361) Predicted protein n=1 Tax=Physcomitrella patens subsp. patens RepID=A9RVX3_PHYPA  E=8e-32 s/c=0.71 id=35% cov=72%
----LYEDQYIIGVSKPGTLLVHnnkaSSPLEKQRNAFLKNMVEAQLtaGQKVSPVHRLDRPASGAIIFSKSAVATRAAQASLSHPACIKEYVVLARGTTPDFFICDEP-----------VNDEKGAPKSAVSQCEKI---------LDLPESRCSLLKVVIKTGRWHQIRKHLNHRAHHVVGDVKHGKGKTNRFFRENHKMlsGRIFLHAARLTFPHP-------------------------------------------------
>UniRef50_A4SY63(88-292:299) Pseudouridine synthase n=1 Tax=Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1 RepID=A4SY63_POLSQ  E=4e-31 s/c=0.67 id=26% cov=77%
----LYQDEHILVADKPHFLPVTPSGLYLHQTLLN-RLKKKTGIQTLSPIHRIDRDTAGLVIFSINPYERANYQNLFRDRTVTKVYEAIaPYSKELANKLPLTYRSRLEESEHFLQMQEVEGEANADTYIELLEASE--------PWARYCL---GPGSGKKHQLRCHLNALGAPIKHDQIYPVLTPYQEYDLDFSKPLQLL-AKEIAFKDPISGE---------------------------------------------
>UniRef50_B8CVD5(14-194:237) Pseudouridine synthase n=15 Tax=Shewanella RepID=B8CVD5_SHEPW   E=1e-30 s/c=0.75 id=27% cov=70%
MYQIIADEADFIVICKSANIHFH----SQDGSAGVVAQAELDLGIKLYSVHRLDTMTSGLLILAKSSAVAAEFTRQFSEHKVQKYYLALAKGKPKKKQGWVIGDMAKSRRSMHKLLRSMDN--PAKTQF-----------FSHSVGDGLRLYLLKPLSGKTHQLRVALASIGVPILGDELYGGDASDRG----------YLHAYSLNF----------------------------------------------------
>UniRef50_Q2JFI3(2-274:304) Pseudouridine synthase n=2 Tax=Frankia RepID=Q2JFI3_FRASC   E=1e-30 s/c=0.49 id=28% cov=80%
----IYEDEAILVLDKPVGISV---MGERHDTDLV--TLAGDDGEELFPVHRIDKVTSGLVLFARQLRFHGDLTRQFQRRTVDKRYLVLTRTRgLPASGTVDLPLsVGRKSRVRVAANRADIMADLAEvaplaevadlgevaplaevaplaevadlgeaaplaeaaraevgptgagagagvGRWTVppaavfphVRTYPSVTTFIRvWEGGEYTLLAVTPVSGRRHQIRVHLAWIGHPIEGDPLFGRDATA----------RTLLHSWRLAFDAAWaGGSRIEVEAPPGADF---------------------------------
>UniRef50_Q6NI05(46-240:243) Pseudouridine synthase n=1 Tax=Corynebacterium diphtheriae RepID=Q6NI05_CORDI  E=1e-30 s/c=0.69 id=29% cov=73%
---------DLLVVDKPCFLPATSNGRIVAETVQTRARIREN-NPHIVPLHRLDRLTTGILLCSTNPETRATYQQLFQHRAITKRYIAHVAGPIPFGPQWTE--IALGMRKMGPRVVVDPTGTLTRTRVRRLEEG---------------VVELQPATGHTHQLRVLLAWVGCPIIGDDTYPVDRRRRIYDFSKKLE---LYATSLEFVDPVSNVTRRF-----------------------------------------
>UniRef50_Q7VIG5(59-242:245) Ribosomal pseudouridine synthase n=2 Tax=Helicobacter RepID=Q7VIG5_HELHP  E=2e-30 s/c=0.73 id=30% cov=70%
---VLFTDEHILALEKPPFI--------ESYDLSNMF-------EGWHLLHRLDRETSGVILLIKEGSAfHIKAKEAFKNQEVYKEYVCLVHGILADSIEINKAIS--TTKRGFAKSRIDKKGLNALTLLTPLSIM-----------GKKTLLKALIKTGRTHQIRVHCQSINHPILGDRIYGKNDE---------AKRLMLHAHKIALL------GYEFTSPLPKELR--------------------------------
>UniRef50_Q2I6L3(1-197:197) RNA pseudouridylate synthase n=1 Tax=uncultured delta proteobacterium DeepAnt-32C6 RepID=Q2I6L3_9DELT  E=4e-30 s/c=0.68 id=32% cov=76%
-------------------MAVHAAGPVDPEAPDLMTWARtHFDAPGLAPAHRIDKATSGLLLCSPDPRVRARVGHWLAQGQVHKEYRALVFGHTHRSGRIDRPLMDRRRGRRL----------DACTRFRRLATA-----------SQLSYLAVYPETGRKHQIRRHLRGLGHAIVGDTRYGPTHQRPLPGCP---GRLWLHLRQLELP-----EGLTFEAPLPPALVAHLERLGIADTQPSKD----------------
>UniRef50_C7RAZ2(84-301:305) Pseudouridine synthase n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7RAZ2_KANKD  E=4e-30 s/c=0.61 id=27% cov=79%
---IIEHNEHFLIAYKPHFLPVMPGGVFVNECL-QQRLIDKTGNPNLQAVHRLDRDTAGLVMFSTNPHTRSDYHQLFAQQNIKKHYQAIAKTqageslsgkswHIKNYLARSEPqfIFQNLDTSPDDTSPHDKDAQYAES-----------LIHCEDDNLQLGLFTLSPITGRTHQLRLHMMSLGFPILNDRFYPSL--QPKQADNFSQPLQLL-AHKLSFIDPVSKEPRAFTSPV-------------------------------------
>UniRef50_A3QIB6(96-309:313) Pseudouridine synthase n=4 Tax=Shewanella RepID=A3QIB6_SHELP   E=5e-30 s/c=0.62 id=26% cov=82%
---ILYLDEQIVLANKPHFMALHPG-GEVINQCLINRLRERTGCETLIAAHRLDRATAGIVLLVKQSDSRDAYHGLFRHGQITKEYQALARLTPELLAEYHA--GKLSLPRRWTVKNRIDKGTPSFTmRIVDGEANSHSEIALVSVEGEIGRFELMPITGKTHQLRLHMNSLGMPILNDNFYPTLLPRSAEDVAQPMK---LLARRLAFTDPVTGRKLDICLP--------------------------------------
>UniRef50_A5IZG0(83-263:284) Ribosomal large subunit pseudouridine synthaseC n=1 Tax=Mycoplasma agalactiae PG2 RepID=A5IZG0_MYCAP  E=7e-30 s/c=0.73 id=25% cov=69%
--EIVYEDDNILLINKKAGTIVHGDSNCLDNQVFSYFKFRQNSAFRPSHVGRLDKWTSGLIMYAKNYQTLTELNH--KTEFLDKIYV-LKSDYNPHDEIVSVYIHHDELQQKMVATKNmqHPNDKIAKTRF------------FKKDNKLYA----QLFTGRKHQIRATLEYLGYPIYGDSKYG--------SKTKGTKRVYLHCYKLKF----------------------------------------------------
>UniRef50_A4S4A1(81-266:357) Predicted protein (Fragment) n=2 Tax=Ostreococcus RepID=A4S4A1_OSTLU  E=9e-30 s/c=0.72 id=31% cov=67%
-VRVLTVNDDVVSVWKPATVPVHPTGQYRRNTVLALLAASRRDLGRLFPIHRLDKNVSGLLLLARSSEAANEMRVKMEAREMRKEYVARVRGAFNdgdatpvsnveslgFDSKGRVAIWRGKKGVTDLDERTLKSFKDASTKFTCIKTL----------VDGTSLVRCEPFTGRSHQIRAHLAMLGYPIANDVAYGG-----------------------------------------------------------------------------
>UniRef50_D2VYL5(155-433:464) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VYL5_NAEGR   E=9e-30 s/c=0.47 id=26% cov=65%
-IRVLYHDDEFLVIDKPSSIPVHPAGRFVKNSL--HYLLESALGRKLFLIHRLDKVTSGVLIHTWNAALAKSYQDTMKEGNVRKCYLAQVYGEFPetenMSGEHVLLNGQSFHKDKEGFIHvknkmvykqndwtfiwradssengsDSTDPKNTDTAYTLVKRIYYDPASSR------SIVIAIPITGRTHQIREHLRVMGYPIIND----------------------------------------------------------------------------------
>UniRef50_Q4UIK0(136-350:441) (RNA) pseudouridylate synthase, putative n=2 Tax=Theileria RepID=Q4UIK0_THEAN  E=2e-29 s/c=0.61 id=26% cov=66%
-VPVVYEDDQYIVVSKPTSIPVYQTGTYNYNSLMeiMKREIPSCRDLKLFTVHRIDRLVSGLVAFAKSSQDASNLSQAIRDNEVKKVYIARVKGDFSYlintsnsdnkesDGDADNSLENVFESIGYMRVIskkegkyefvgendEDESYKRSVTRFKLIKYNKDLHE---------SLVLCSPITGRTHQIRAHLKYLGYPISNDPWY-------------------------------------------------------------------------------
>UniRef50_Q2BL24(81-291:313) Pseudouridine synthase n=1 Tax=Neptuniibacter caesariensis RepID=Q2BL24_9GAMM  E=3e-29 s/c=0.62 id=30% cov=64%
----VWESDELMAINKPPLLPVSRTTRNLYMTLISL-VRRQTPYPDAQLLHRLDTETSGLILLAKNREADRKWKPQLAKLIRRKVYQAWVHGSPNWDHlLMECELSEKAGSDIRSQVYVVEpqsdsqylKPRPSKTEFLVLQRAGSK-----------SLIQCELFTGRKHQIRAQLAHLGHPIIGDKIY-------------------------------------------------------------------------------
>UniRef50_A9FG19(81-298:326) RluD4 protein n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9FG19_SORC5  E=3e-29 s/c=0.60 id=27% cov=81%
----------LLVASKPAALPTEP---ERRGTRSLVTEVAELLGLRdlPHAASRLDVGVSGAVLCATGARGRRHVVAMREAGRIARVYVGVAGGRVEGSGTWDAPIGAARARGGRSLpAVGGADAKDASTHYR-------AVASAGGGAAPATLLRLDPVTGRTHQLRVHAAHAGAPLLGDRDHGGARSVTTARGRvIPLSRVALHALRVTVPDER-GELCAAIAPVPDELRELW-----------------------------
>UniRef50_B7G895(96-326:383) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G895_PHATR  E=6e-29 s/c=0.56 id=24% cov=77%
-VPVLFQDDQILVVHKPSGVAHHNdADTGRLGILNLIRHQqttgRFAYPHRLYGVHRLDRVTSGILVLAKTPGAAQILTQAWREDRVTKYYVGLSGNKATTSKQGHVRGRMIRGRRRSWLLTRETHGSNvAHTRFFTagLGHLAPPSSTLTNVSPK-TLLLFRPTTGRTHQLRVAAKSVGLPLWGDPVYRDGRHRTENASTP--SRTLLHAA--------------------------------------------------------
>UniRef50_B6KIC7(99-474:493) RNA pseudouridylate synthase, putative n=3 Tax=Toxoplasma gondii RepID=B6KIC7_TOXGO  E=7e-29 s/c=0.35 id=29% cov=87%
-LDVLYEDDDIVVINKPAGLLTHPpqltveniDKHNRLGSVVqrlfykflcsdgmfpetflplakqaafrklnrngctmasrkteehpfkestgdaggeapvegprgptaecadgpssvrmprMQLALPEAISRPVSIVHRLDIGTSGALVAAKTAAAAENLKLQWAERKVLKGYIGLCTPEIHSLHEVDAPLRRHPTQRGRMealsnesrssfHDVCDETAQKDHSSYRIGAKPGVSVFAPLGGNGAYGMFAALALTGRTHQIRAHLEYIGHPLLGDLVYGNQTVNEELRrfvknvvvnprhhREEAATRMtrkevqvsccdagpdvlapagnvkvhmrpFLHAYFLRFAHPRTGAAVNIKALPPAD----------------------------------
>UniRef50_B8C9J1(100-280:280) Predicted protein (Fragment) n=1 Tax=Thalassiosira pseudonana RepID=B8C9J1_THAPS  E=1e-28 s/c=0.71 id=28% cov=66%
-VQIVYEDNSLLIVDKPSTIAIHTSGAYNYNSLFEILSYwnpQAYGLGRLFTVHRLDRLTSGLVLIAKTPELARSMGKCIMERDgCEKLYLTRVKGKFPLNVMEkvasDGGIdaQNDNEHPHLTEEADRKGIKPAQTSFTLL---------TYDAVSDTSVVLAKPVTGRTHQIRLHLQQLGHPIANDHCY-------------------------------------------------------------------------------
>UniRef50_Q3IGX9(9-217:226) Pseudouridine synthase n=4 Tax=Alteromonadales RepID=Q3IGX9_PSEHT   E=2e-28 s/c=0.61 id=26% cov=69%
-LKVVHSHSDFYILAKPAGLNFH--SEDAAGFVVLAEQ---QLNEKLFAVHRLDKVTSGLLILARNKLAAAKFTQMFTEHTINKFYLAISDAKPKKKQGWIKGDMAKSRRGTFKLLTTTAN--PAISRFYSVSYKPGFRGYI-----------LKPYSGKTHQLRVALKSIGAPILGDTSYAGAHSA----------RTYLHAFALDF----------------------------------------------------
>UniRef50_C7LP84(16-189:232) Pseudouridine synthase n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LP84_DESBD  E=2e-28 s/c=0.74 id=33% cov=67%
----------FVVVHKDPGLDFH----DCDGRMGLCSLVRDRLQARVFPVHRLDKATSGLLLLARSREWAAALAGLFRERAVQKYYIALSDLTPGKKQGLVQGDMVRSRRGSWKLARSME--RPARTRF-----------LSWSVRPGMRLFVLKPMSGRTHQLRVAMKSLGAPILGDSLYHPIVPDWP-------DRMYLHAHTLRF----------------------------------------------------
>UniRef50_B8BW13(331-588:614) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BW13_THAPS  E=2e-28 s/c=0.50 id=30% cov=87%
-VEILDQGENYVIASKPASVIVHHSSWTgkrsdpkrrWKEATPMLQRVRDATGRRVNLVHRLDRGASGCLVfsFAQNEEndngetppcsVTKSMIEAMQHPDARKTYLALCDG----DGTWNGVDYLNKGWFTFNNPVKDEWGKlidDCCTDIRFVASKVLPPTSDEDPDNmegrKVSLILARPKTGRWHQVRQHLSSgtIGHALLGDSTHGKSRTNRIWKKDRHLmkERTCLHLSRVQI--PATEYTpaIDISCPLPSDLIKML-----------------------------
>UniRef50_A8Q8B1(93-274:937) Putative uncharacterized protein n=1 Tax=Malassezia globosa CBS 7966 RepID=A8Q8B1_MALGO  E=8e-28 s/c=0.69 id=26% cov=65%
-VRILHRDDsqgRIVVV-KPGSIPVHATGRYHHHTLVEMVKEQAKL-QNLYTSNRLDRLTSGIMVCSTTKEAACELGNDFNAGLVNKAYVCRVVGRFP-DGIVDCTEPILSVDRQSGLNIVHPKGKECRTLFQRLSY---------DAATDSSVLVCRPITGRTHQIRVHAQWLGHAISNDPLY-------------------------------------------------------------------------------
>UniRef50_UPI0001BC5679(88-271:291) tRNA pseudouridine synthase A n=3 Tax=Fusobacterium RepID=UPI0001BC5679  E=1e-27 s/c=0.68 id=26% cov=70%
---IFYQDTDILVFYKKAGELMHKGSSHDYGLAEQFQAY--FQNEDFHFVNRLDKETSGLVLGGKCLKIVRELAEAIKKRTIIKKYYIIIEGSPEKNHFSLKTYLKKGENKVLESQTAKEEYKECSASFSVIRK-----------NKEYSLLEAVLETGRTHQLRVQLAGIGFPILGDIKYGKKR----------AKRMYLHSHLLKI----------------------------------------------------
>UniRef50_UPI0001793647(140-259:259) PREDICTED: similar to RluA-2 CG6187-PA, partial n=1 Tax=Acyrthosiphon pisum RepID=UPI0001793647  E=4e-27 s/c=1.03 id=26% cov=44%
-IEVYYEDKDVAVVYKPKGMVVHPAPGHYTGTLVNglMYVIKDLSGingeIRPGIVHRIDKDTSGLLMIAKNDIAHRGLVEQLVDKTVTREYTALVHGNIPHEfGTIEAPIGRNPKERQEM--------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5DGR1(245-564:567) SJCHGC01427 protein n=1 Tax=Schistosoma japonicum RepID=Q5DGR1_SCHJA  E=4e-27 s/c=0.38 id=30% cov=88%
--------ENVIIMNKPYGIASQPGADCKHNIVDLLPRIESMIRKRnhraskvkeetvdeLSTVHRLDKDSTGAMLIARNRDASLKLQEAFARRWIKKDYLCITVGIPRSEyGYIQLPLVERNFKEFHKMCIPkldrhlqelackqtqldenDETNEYDVTDAFSVLYNKMQTNNNNQPVTWYHLLDqrndaglmlCSTLTGIKHQVRAHLAFgLQTPILGDHKYSHGEYLAPQRLPKHLLealnvRQpkvrylalHLHASSLHLRvspsssssscenffdfvrslenplHTVTGstrHPLKFHAQLPIHFRENLKRIGLK-----------------------
>UniRef50_Q47XX3(112-289:318) RNA pseudouridine synthase family protein n=2 Tax=Gammaproteobacteria RepID=Q47XX3_COLP3  E=4e-27 s/c=0.69 id=31% cov=65%
---------------KPYGMLSQGSKWSDHCTIARFAQQNLPNERPAFIVHRLDRAATGLIIVAHSKSAARALSHMFEHHQLEKHYQIIVHG-------------DHRKRAQPDIIDSDVDGKKARSTFTCLAYDEM---------TDQSLIKVKIDSGRKHQIRLHAASIAMPVVGDRLHG-------IADKDEQRNLQLCAVSLRFVCP-------------------------------------------------
>UniRef50_Q4D881(103-444:474) RNA pseudouridylate synthase, putative n=4 Tax=Trypanosoma RepID=Q4D881_TRYCR  E=6e-27 s/c=0.36 id=25% cov=80%
-IHVVHDDDAVIVCVKNGNLPVAEGGRYSGNTLVGLLERRDavsfvsekysaarqkmdqtreedgdagvsvhKVPASYYPIHRLDKETTGLVVLAKQLAAARALSRQFekqseritaqvskrtdpagdglstavfekllaEEKVVTKVYVAVLAGAGPegadfvmcdrigllFDSLWNEGDTEDAKKHNKLKKLkmacfpvnlkenPKRHGRPAASRVRILSSDK---------KLGVSVARVDILTGRTHQIRIHCAQLGYPVLGDKLYetttpgvvggccavpddtyiarakGNEGLVSAAAPRLRVKRHLLHAAVLSFLHPISEERL-------------------------------------------
>UniRef50_D2VN10(126-309:314) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VN10_NAEGR   E=9e-27 s/c=0.66 id=25% cov=60%
-LNILFEDDFLIVLDKPKFMTVHPSlkpkPRNTTGTLVNALLFHTNGKLstcgsceehyRPGIVHRLDRDTSGIMVVAKDDETHLALKKLFENKnvgdennedKITRYYQALVENELNQsEGRIEIYIKRHHSMPSKREVTNnalETGAKLSITEYKEQKTFPVNNLTGCKV---LTLVRCKLLTG-----------------------------------------------------------------------------------------------------
>UniRef50_D0N321(279-460:556) RNA pseudouridylate synthase, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0N321_PHYIN  E=1e-26 s/c=0.67 id=29% cov=58%
-VRVVYEDDDLIVVSKPPSMPTHPCGAYRHNSLHTILQATRPDLPQLNIVHRLDRLTS-------------------ADRQASKTYLARVRGRFPDvlssevqdklvtqakeicpasiitfpeegAVLISCPLRCLSARDGVWECHEE--GKPSETLVRLVRTDKCT-----------SLVKCKPVTGRTHQIRLHLQLIGFPIANDPCYGG-----------------------------------------------------------------------------
>UniRef50_Q38EM9(999-1272:1279) RNA pseudouridylate synthase protein, putative n=4 Tax=Trypanosoma RepID=Q38EM9_9TRYP  E=2e-26 s/c=0.45 id=25% cov=73%
----------VAAVDKPAGMSTTLHVGHPHLLDFLAGNLPWKGPSAPvlfqhGLVNRIDLGTSGLVLVADTEASLEEARRAsIVERCVEKVYRALVLHCPPPISRIDTSecwylnpcgiimcdvlangadfslqIAAYNSSKGGALPVGAMDRRSATTTYRVLQYF---------PRSGVYYLEIHLHTGRRHQIRQHFARLCHPLLGDGRY--SRRAQVVGEEFGLQRPALHAVRVTLT---------------------------------------------------
>UniRef50_B1VE82(143-420:422) Putative pseudouridylate synthase n=1 Tax=Corynebacterium urealyticum DSM 7109 RepID=B1VE82_CORU7  E=3e-26 s/c=0.43 id=28% cov=84%
-LRLLFQDANLLVVDKPPFMATLPRGQHIVETALV-RARRQFGIPELSPAHRLDRLTRGVLMFTVRPEVRGPYQRLFDERVPEKTYEAVtlpadeapFPPIPRFRGWQEWPAPTPEQPWLLRHHMVKERGRlatylvepeapaidataptdsgaaaaspshdmflappNALTKVVGVrsERRALAIAGGPTPRERRVLVwELVPETGKTHQLRVALRTLGLPILNDPLYEELSdealrdptaalPSPPFAGEEDFGRPMeLTAQRLRFHDPLTGELREF-----------------------------------------
>UniRef50_C4XE77(99-275:296) Putative uncharacterized protein n=1 Tax=Mycoplasma fermentans PG18 RepID=C4XE77_MYCFE  E=7e-26 s/c=0.67 id=22% cov=68%
-FKIIYEDDNILIVSKPINLAVHSENNCLDKQVLSYLKYNQKDSFKPSHVGRLDKVTSGLMIYAKNYATLVELN--YKTGFFEKIYK-LKSDFNEVKKLVEINIQHDE-KLHKMVVTNNAKDPLAKTLF----------------YTKNNEIFASILTGKKHQIRLSMSHLKTPIYGDIKYDGKK----------ADRLYLHCYSITF----------------------------------------------------
>UniRef50_Q55AQ0(24-290:316) Pseudouridine synthase family protein n=1 Tax=Dictyostelium discoideum RepID=Q55AQ0_DICDI  E=1e-25 s/c=0.45 id=27% cov=76%
----IYLDKEYIVVNKPFDVNIDDETGERLTTVVKYIETEYPEHFgNVRFVNRIDYATSGLVVVSFNKKSTTVAMELFQSRETSKTYLAIVHGHMEFDeSIIDKPIQYDtsDENSFKMCVVEDinnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnqstttttitttttiknksNPAKASQTSYKVLERGYLKINNDEYIP--ITKVMLFPKTGRRHQLRVHLLSIGHVIVGDETYGPKDST--------IHRMMLHSWKLIlpFKH--------------------------------------------------
>UniRef50_C4QP03(45-292:370) Ribosomal pseudouridine synthase, putative n=1 Tax=Schistosoma mansoni RepID=C4QP03_SCHMA  E=3e-25 s/c=0.47 id=26% cov=69%
-LRVVHENQGFLVINKHPELLI-NCTTPWINCLTLQMQLFYNRPRYVnwklknmfHFVHRLDCPTSGLICIAYDTKAASMIRRAFENKEVKKYYLAIVWGYvgsfcdsglsssfVKHESKLVHHIQMSIGSFRYLWPNTGRKQKIIvpITHpecYRPRESLTTVIVLdyGKLMGEPATHILLIPETGRRHQLRVHCAiGLGHPIAGDTTY-------------------------------------------------------------------------------
>UniRef50_B8BXW5(131-428:438) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BXW5_THAPS  E=2e-23 s/c=0.37 id=23% cov=68%
--EIIYSNNHLLVVNKPAGWKSQPGDGGGTGSMsnavdpkCLLTHLQNQSlgggsqKNFISPTHRLDQPCTGALIFAKNGKAASRVQVAWAKRNVKKCYWVVVEggigngggrtnglellqsrsmqlkqsglyqmsavlktgggkgrgtsgntGSNKPAGGGSVTVSPVPPNLTSKDIGDVKHGRICHIEWKHL----LALPSSRNSPSNRHLLSVTTDTGAKHQIRAMLAlAGGAPISGDLRYGN-----------------------------------------------------------------------------
>UniRef50_D2L201(87-269:313) Pseudouridine synthase n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L201_9DELT  E=2e-23 s/c=0.61 id=28% cov=69%
-VPVLVQTGDFAAVSKPAGLHSaaiaHGGGQSLDDLLPAL-----FPDRAAILLSRLDRLTSGIVAVALTPGAGTRYRDLEDAGQVAKDYLAVVHGVIADPFVVDFRLDTADRAKTRVRFKSEPDPLR-HTQVEPLDRLD-----------GLTLVRCRIAKGARHQIRAHLAGAGHPLVGDPVYGRGEG----------ERLHLHCAALA-----------------------------------------------------
>UniRef50_C2MA71(89-303:341) Ribosomal large subunit pseudouridine synthase family protein n=1 Tax=Porphyromonas uenonis 60-3 RepID=C2MA71_9PORP  E=2e-22 s/c=0.50 id=22% cov=78%
LIEELYRDEQFIVLHKRPGIPTISVGGASKSSLfqVVTHHLKKvDPNEKIFLLNRLDRDTEGIIIVARDRQLQQDLLAEWHSFVLFNSFEAVVLGALDTsSGELTTRPTKDKKRGSDKRRTSTSSGrdkKPAsfRASYEVLST-----------GPYITRLSLSLLT-RNNSIRSTLASIGHPLLGDHR------ANDSIAPDLSKYLALRATELAIFHPIKRQKMLFT----------------------------------------
>UniRef50_B6AH65(140-394:527) RNA pseudouridylate synthase family protein n=1 Tax=Cryptosporidium muris RN66 RepID=B6AH65_9CRYT  E=3e-22 s/c=0.42 id=25% cov=68%
---ILYNNKHFLAVYKPYGIPCHPqgrfhklsltnivmSKYFRSETEVIIDnkaasRIINDDKLYAHPINRLDRVTSGLVILSKNCDSTRLLSKVIS--KSHKYYLAHVEGDFsslehvdigklfkstqlvkiqnlemglniNFGIKCEAPleIIKDRVGDSLMTKVSFENGKSALTWFFPLKIEYLSQEDRKKIKLDqvnfesinichkpNSYVLCKPVTGRTHQIRAHLQYLGFPVTLDHLY-------------------------------------------------------------------------------
>UniRef50_C1EC23(120-312:498) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1EC23_9CHLO   E=5e-22 s/c=0.55 id=28% cov=65%
---VLLEDSKLVFVDKPAGVPTLAGCGpklqgeNNATRLLNRTRAENATGAddgELFAVNRIDKPVSGVWILAKgSRLAARCRAALAKPGHETKTYLARVRGAVVGPIRIDAPLS--VGADGRATTSGGADAKPAVTLVHPVARYPPPW-------DDCTLVACRLErSGRFHQIRCHLASVGVPIANDATY-------------------------------------------------------------------------------
>UniRef50_C8PKX0(69-466:470) Pseudouridine synthase n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PKX0_9PROT  E=1e-21 s/c=0.27 id=31% cov=81%
-LKPIFECDAFAAFDKPSGILSHPSGRNSPYN--MYDEIWSLYGQDACVAHRLDLETSGILIVAKDKDAARELKECFEQRRVMKSYLALVQGDLReglrgdlqsaacngeiescyalgfdeicgskfagdavslpssvsdlrdtlalkgtgnkfgfnilsngasrglwcdalsydaqvkfnsgaptgdvdsrsefddlscgvsdklkpaitmssadnghkpcalsaakslpatskgcvnlkkfepakyakfseklkflkdfEGFVIDAPIAPSGEfADLKIRMKISRDSKEAITLIRPLRYF---------SDIDASLIECYPLTGRQHQIRLHLFAAGAPILGEPLYGLSREQAERIldkkmdetervRTTGAPRLLLHANAICFE--LGGERYEIKSKFD------------------------------------
>UniRef50_C5YIB1(182-428:439) Putative uncharacterized protein Sb07g027030 n=1 Tax=Sorghum bicolor RepID=C5YIB1_SORBI  E=5e-21 s/c=0.42 id=30% cov=72%
---VIHRDSAILVLNKPPkvpmkgHLPVHNSM---DVLAAAALSYGNKEGPKLTW-----------------NKACEAY--------VQK-YWALVIGTPKeREGVICAPISKvllddgKAERVILAHPSGIDGAQEAITEYRVM----------GPTINGCSWIELRPLTGRKHQLRVHCAeALGTPIVGDYKYGwfvhqtwkqnpQPDFEPFTGEPYKLRRpegleiqkgsvlskvplLHLHCREMVIPniakflsstgewHengaPWAKEKpnlLRFVAPMPPHMK--------------------------------
>UniRef50_C1SGK2(62-226:248) 23S RNA-specific pseudouridylate synthase n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SGK2_9BACT  E=2e-20 s/c=0.61 id=28% cov=63%
---IVKEFDHIVFFDKPAFM--HTDLQKPDDPITMTDVIMAYSNEFSFIS-RLDYTTDGVIAAVRDD---------FFVFETRKVYLAHVEGKIEKPFVMDNLI--DADKRRKVRVLEKPGGY--KTTFTPVS-----------FENGLTLVRAEMENASRHQLRAYLAHKGHPILGDELYGGTA----------ADRIMLHC---------------------------------------------------------
>UniRef50_B7FTR4(233-434:497) Predicted protein n=2 Tax=Bacillariophyta RepID=B7FTR4_PHATR   E=2e-19 s/c=0.49 id=23% cov=68%
----LYEDTTFIVVDKPPLLPTQPDSSNYVE--CCPGCVQDNLGPftdiqgnevvRPLLCHRVDSCVGGCVVLSKDGNGQKVFQEMQRERKLRKLYLAVTTQPVPlgmHLHWMWAPQSARGKSGGPPCQLVSHAPPESRRKARqfwnrcVLEVVKcEPIKIGKEDSHTYDPAgkvhyqsTIRLVTGRKHQVRAQLASLGAPIIRDSLY-------------------------------------------------------------------------------
>UniRef50_A3BN26-2(130-317:400) Isoform 2 of RNA pseudourine synthase 6, chloroplastic n=2 Tax=Poaceae RepID=A3BN26-2  E=8e-19 s/c=0.51 id=21% cov=66%
--------DNYVVLDKPAATSVGGATDNIEESCVVFTSRALGLETPLMTTHQIDNCSEGCVVLSKTKEFCSVFHGMIREKQVNKRYLALTT-APVSTGIITHYM--RPINRAPRLVSEDHIKGWHVCQMEILDCKKVPWPSSLirkvHKVDNCGWpqqeaayeCKINLLTGKTHQIRAQLAAIGTPIVGDSAY-------------------------------------------------------------------------------
>UniRef50_Q05FL2(4-198:204) Pseudouridine synthase n=1 Tax=Candidatus Carsonella ruddii PV RepID=Q05FL2_CARRP  E=2e-18 s/c=0.49 id=23% cov=60%
-FKINYFDNNIIVINKPIGIEV------KNLLNVNFIKLNDKI-PNFGILNRLDKYTSGLILVAKNFYFYFYFKKLIVKNLIKKNYISFVNKKIK-KGFVNVDIFKKKKSSIIKNNKKSI------TYYKIIKEKK-----------NFSFLNICIKTGRTHQIRLHMMHIEKKIFNDFYY-------------------------------------------------------------------------------
>UniRef50_C1EHD0(184-468:481) RNA pseudouridylate synthase n=1 Tax=Micromonas sp. RCC299 RepID=C1EHD0_9CHLO  E=1e-17 s/c=0.33 id=26% cov=68%
---VVHEDDAILVVNKPHRLPSmaHESNGVEHCAGCLERSL-GLSPSTLRVTHRLDSSTSGVLVLGKTATAVREFNDSVAktpgSKEIVKSYaalvyakHAVPLGLMTHWMYpgpfgPGAFHGRTLRRSRARLVRSSADGERGddtggqgtgkrwkrcelrvvscdratqsqvdtwRTLFdRELERARKPfdggaddplvsggdSPGGDSPGASVWAVRVELVTGRTHQVRAQLAAAGAPLLGDSLY-------------------------------------------------------------------------------
>UniRef50_C7LVN5(79-263:281) Pseudouridine synthase n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LVN5_DESBD  E=1e-17 s/c=0.50 id=26% cov=61%
------RNESFAALAKPDGLHTVAG----QEAACLESCLPGLGLEGWELLNRLDCLTSGLVLAAAEKRDAAAYKVWQDAGQVSKWYLALARGEVATL-ECRGRILDDKRSVVRVTADEDEPLRW--TRVRALRQID-----------GNTLLLVKIFKGRRHQIRAHLAHAGHPLIGDPVYG------------------------------------------------------------------------------
>UniRef50_UPI00004D58A9(3-263:264) RNA pseudouridylate synthase domain containing 3 n=1 Tax=Xenopus (Silurana) tropicalis RepID=UPI00004D58A9  E=1e-17 s/c=0.35 id=22% cov=82%
----------LVAINKPQGLSITGKEQEVSVSSLLADLQQHlGLGSDLHIVKAAPKESSGLVLLSTCHMTTKRLEDYYAlCRKAQKptaSYCAVMAGVPhPAEGEIKAALKLEriedwqlvvPVTDPSKGRLERREIKRTLTRYKVLDSAD-----------GCALVQLQPMSVFQAQLLVHSTLMFCRILGDHTYSARvgkvlGENIFVPMDIALPRtqvleenvlrrmhftqqqmhrmpLHLHFQQLMIPgeSPAEGDTF-LDAPPPPFFQRTLQLLG-------------------------
>UniRef50_Q1M2R1(1-176:186) Putative pseudouridine synthase (Fragment) n=1 Tax=Arcanobacterium pyogenes RepID=Q1M2R1_9ACTO  E=1e-15 s/c=0.49 id=32% cov=55%
-------------------------------------------------------------------------QDMFAARKVTKIYEAVARcvdlgalagnlpgvakaeaGHLGEWVRVDLRLAREPGAIA---VHVAEGEPNAVTYIRKVRQLRATPELVPAAADGeatappaLALYELRPITGRLHQLRATLNYLGAPIAGDPLYPKVLSLEDTAAR-SFPTQLL-AAQLSFVDPVDGEQVHI-----------------------------------------
>UniRef50_B5QFC3(1-152:152) Putative ribosomal pseudouridine synthase n=1 Tax=Campylobacter jejuni subsp. jejuni CG8421 RepID=B5QFC3_CAMJE  E=1e-15 s/c=0.57 id=24% cov=49%
------------------------------------------------------------ILLCKDEDFRKLCIEEFKKHRVYKSYIAVLDGVLAEEVEVNEPIFTIKVKGG-ALSKVSKDGLSALSIITPI-----------MMQSKKTLAKIVIQTGRTHQIRVHAKFIKHGVVGDEKY----------AKISSDRMYLHSYEIKI----------------------------------------------------
>UniRef50_UPI000194D267(27-193:270) PREDICTED: similar to RNA pseudouridylate synthase domain-containing protein 3 n=1 Tax=Taeniopygia guttata RepID=UPI000194D267  E=1e-15 s/c=0.51 id=26% cov=61%
---VVHREGALLALSKPPGLPILGRPGDlSLDSLLPALRRRLGLAAELHVVKAPAREYSGLVLLSSCYHTTKKLHQFFtsarRRGQYPATYRAVTVGVPaEVEGEVSTGLCWQQQGDRAMST---------LTHYRVLST-----------TGGCALLQLQPRTAFPEQLQVHLTLLLCPALGDHKH-------------------------------------------------------------------------------
>UniRef50_Q9U190(1168-1446:1469) Possible RNA pseudouridylate synthase n=3 Tax=Leishmania RepID=Q9U190_LEIMA  E=1e-15 s/c=0.31 id=25% cov=68%
-----------------------------------------------GLVNRVDVGTSGVVLVARTADAlHGAADAMIREHHMRKTYRALVQRWPPFSssssssastvrydddnaaaaplfsvspflspmpsavvcapvyaaGATASSISRRSALPLSHGRQLQSPGQPsadalaasragstlswsssvpvslsslehvhqqyatlhaalqdqrnAITRYRVLEYF---------ASAGVAYVQVELCSGRRHQIRQHFAQLGFPLVGDARYHAGVVAGHAGTTLGMRRAALHAYTVDILATTDGddlasseevpDRVVVQAALPADMHRAL-----------------------------
>UniRef50_C1MNL7(209-524:548) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MNL7_9CHLO  E=2e-15 s/c=0.27 id=27% cov=69%
---VVYEDEETLAVNKPHALPTQAHESNAAECVpgCVARALGFTGGvtdgdDALLVTHRLDASTSGVVVLGKTLGAVRAFNASIAgGKRVTKTYVALVENasnvrrrgvtvedattppPPVPLGRFVHYMYPGPFGasalggrgarrsnarllRRRAPSASDGDAKPwrrcelvvrscarasprdvaawralfAESvegnanweAARGVDDGSRDEPSRRAGDDAVYEVEIELVTGRTHQVRAQLAALGFPILGDTLY-------------------------------------------------------------------------------
>UniRef50_B8LBG7(230-497:536) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LBG7_THAPS  E=2e-15 s/c=0.32 id=25% cov=70%
----VYVDDDLgfTVLNKPGGIPTHSTISNHAEDVVSMYRasLKEERGDEAHTPHvsipiRMEPEMYGLTLASTKKEFCAYITKQLAASKelhdenssngnsipVKKSYRVLVCIKNPDDidriekmvGKTLEHYVDPVSPTPKKFVRNKPKSSNHdwqqclmlITSVGDTKFRAACVSSKYTDSNDFTLahrlwcpdmdhpaedlgvsyvmqLELELLTAKPHQIRGQLAALGCPIVGDTPYGGG----------------------------------------------------------------------------
>UniRef50_C8WGQ8(74-243:282) Pseudouridine synthase n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WGQ8_EGGLE  E=3e-15 s/c=0.50 id=29% cov=62%
-----------IMLHKPAGFVT--TMSDPQGRRTVAELVPTERYPGLFPIGRLDFDTTGLLLFSTDGELGNGL--LHPKHHVTKRYLACVEGRPTERdlALLRRGIELDDGPTQPADVRVVEGG--AARHAERLleipaavppRSSKEYAAVCEGRATRRSIVRLGIREGRKRQVKRMLAAVGHPVL------------------------------------------------------------------------------------
>UniRef50_C8WAL4(71-228:279) Pseudouridine synthase n=7 Tax=Coriobacteriaceae RepID=C8WAL4_ATOPD   E=5e-14 s/c=0.51 id=25% cov=58%
-----------LMLNKPAGYLT--TMKDPQGRPTIVDMVPTDTYPGLFPVGRLDMDTTGLLFFTTDGQMAQEL--LHPSKHVWKHYVAHVVGTPTEEQL---------NRLREGIELEDGPAAPAeveiISDDVKMKNLLAPQGLGKTGGGEpNALVSVTIREGRKHQVKKMLLAIHH---------------------------------------------------------------------------------------
>UniRef50_C5KIU2(27-142:142) Ribosomal large subunit pseudouridine synthase A, putative (Fragment) n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5KIU2_9ALVE  E=2e-13 s/c=0.68 id=28% cov=44%
----------------------------------------------------LDIFTSGIIMVAHTYAAYYQLRHQFKKRAILKKYICLVHGHMDEDsGIIDTNIQTYSSSSNSRSKHIPIS------------SSSSSYSTIINNNKKVSLLEVEIPTGRTHQIRLHMYHIGHPIVSD----------------------------------------------------------------------------------
>UniRef50_Q57VS4(184-573:638) Putative uncharacterized protein n=2 Tax=Trypanosoma brucei RepID=Q57VS4_9TRYP  E=4e-13 s/c=0.20 id=30% cov=66%
----------ILVVHKPAGLPTHASGRYfmnsctamleyvlaprrlhawlvekdpllqslvstihltgRERDELLAYYLTDSMEEDtvpierlPRPCHRLDKVTSGVLLLGISKVAARRVGEALMSKtrqmeeilprrsrfesdegtitfdklhmsgaTVRKRYLARVRGCFPENSMKIRFencpgdknkegvladsnekdttcpinggllIVTKNSHEGRRDATDGMNVKtfvnsvgvpvlftsplrqyrfsenetiyedlnesygtpikemfcqDAMTLCQPLRHYQSDHSHHKDAGTNTeSLVHCVPFSGRMHQIRIHLSDWGHPIVGDVTY-------------------------------------------------------------------------------
>UniRef50_Q47QM5(199-337:375) Pseudouridine synthase n=3 Tax=Actinomycetales RepID=Q47QM5_THEFY   E=4e-13 s/c=0.56 id=26% cov=53%
------------ALNKPRGVVS--TMFDPEGRPTIGDYAAQIGPieERLFHVGRLDTDTEGLILLTNDGELANRLTH--PRYKVTKTYLAKVPGPVPRDVI---------RQIRKGVELDDGFVK--VDSFRVIDNIEPK-----------ALVEIRLHEGRKHIVRRLMKAVGHPV-------------------------------------------------------------------------------------
>UniRef50_B6AJ66(2438-2592:2982) Putative uncharacterized protein n=1 Tax=Cryptosporidium muris RN66 RepID=B6AJ66_9CRYT  E=7e-13 s/c=0.50 id=19% cov=60%
-----------------------------------------------------DDEISGPVLISKSDDSYQNLLNQYNEKEIMAEYVFLCHGQLeKHDGYISFENLATIVCNRIFAKSVTVGSSNCIAKYKVCGIYKHVNST--RDSLLYSLCRCHSTAGSVNKIRAFMSEIGHPIVCDSKFLNNKQ--LNADRRLFPHIFFHCWYLEFLKP-------------------------------------------------
>UniRef50_A3CPQ5(64-197:242) Pseudouridine synthase n=3 Tax=Firmicutes RepID=A3CPQ5_STRSV   E=1e-12 s/c=0.57 id=28% cov=48%
-------------LNKPRGVIS--SVSDDKGRKTVVELL-PQVKERIYPVGRLDWDTSGILILTNDGDFTDEMIH--PRNEIDKVYVARVKG---------LANKEVLRPLTRGIEIEGRKTKPAV--YEIIKV---------DPAKNRSVVQLTIHEGRNHQ-------------------------------------------------------------------------------------------------
>UniRef50_C1FJP2(101-179:179) Predicted protein (Fragment) n=4 Tax=Eukaryota RepID=C1FJP2_9CHLO   E=4e-12 s/c=0.94 id=28% cov=31%
-VDVVAVTDDLVAVHKPATMPVHPTGQYRKNTVLGVLAATRRDLGRLSPAHRLDRNVSGLLLMARNARTASALREALAEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P72581(42-191:261) Uncharacterized RNA pseudouridine synthase slr0612 n=16 Tax=Bacteria RepID=Y612_SYNY3  E=6e-12 s/c=0.49 id=24% cov=55%
-----------IVFYKPYGVLCQFTDNSAHPRPTLKDYI---NLPDLYPVGRLDQDSEGLLLLTSNGKLQHRLaHREFAH---QRTYFAQVEGSPTDE---------DLEPLRRGITFADYPTRPAIAKI-----ITEPDFPPRNPPIRYrasiptSWLSITLTEGRNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_O96199(27-306:450) Conserved Plasmodium protein n=1 Tax=Plasmodium falciparum 3D7 RepID=O96199_PLAF7  E=6e-12 s/c=0.26 id=18% cov=84%
--NILYCDDDYLVVNKKYGMFTFGTSRNKESVLKNLSLLNEDEGKGWNILYKLYSQISGCVLICKN--------KIIKYNSYDNIFLTLVYGKIenvKNMKEKNYYYNEiklylkylPESNIMITTNNYEDINKMKCLKYEVL------NNNIYYQKHNFSLLKLYINACNSQYIKPLLYYsLHTCIVGDNEYinvhkkilqkkknekyiikkepyllynnnnNDHVPNILKSRKFLLKklnkekqgnelKLHLHCLNVTFQYQC-NKIKSICAPVPSHFKDTLHILG-------------------------
>UniRef50_B6W880(1-80:115) Putative uncharacterized protein n=1 Tax=Anaerococcus hydrogenalis DSM 7454 RepID=B6W880_9FIRM  E=8e-12 s/c=0.92 id=30% cov=31%
------------------------------------------------------------------------------------------------------------------MVKGNKGGKRIITKFYPLES-----------KNNFTLLECELITGKTHQIRYSLHKNSTPIIGDRKYSKSKIN---YKKINLNSQALLAYKLVF----------------------------------------------------
>UniRef50_C8NA36(1-73:80) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Cardiobacterium hominis ATCC 15826 RepID=C8NA36_9GAMM  E=9e-12 s/c=1.00 id=25% cov=26%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAQHYPLVGDPLYGLATPSGKGlppevrQTLLAFPRQALHATALTLSHPADDDEITFASPLPADMQTLLAAL--------------------------
>UniRef50_Q87QY8(63-238:238) Ribosomal large subunit pseudouridine synthase E n=244 Tax=Bacteria RepID=RLUE_VIBPA  E=2e-11 s/c=0.41 id=26% cov=55%
----------VIIFNKPYDTLSQFTDGDGRKTLADYIPVKD-----VYAAGRLDRDSEGLMVLTNDGILQAKLTQ--PKSKSPKTYWVQVDGAPQEQ---------DLEKLRKGVELKDGMTLPAK-----VEVIDAPTIWERNPPVRFraniptTWLAITIIEGRNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_Q9CKK7(51-200:241) Ribosomal large subunit pseudouridine synthase E n=61 Tax=Bacteria RepID=RLUE_PASMU  E=2e-11 s/c=0.48 id=27% cov=56%
----------VILFNKPYDVLTQFSDEEGRATL-----KAFIPIPHVYPAGRLDRDSEGLVLLTNNGEIQHRL--AVPKFNTEKTYFAQVEGIPQET---------DLAQLRQGVVLNDGKTLPA----KVRLVPEPNWLWQRNPPIRerkqipTSWLEIKIHEGRNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_Q4D992(538-663:682) Putative uncharacterized protein n=1 Tax=Trypanosoma cruzi RepID=Q4D992_TRYCR  E=2e-11 s/c=0.57 id=33% cov=29%
-----------------------------------------------------------------------------------------------------------------------------------------------------SVVECLLLTGRTHQVRVHLASLGHPIRGDKKYIRLAADSPsiplrtdlrdeeeedeeeeeeeSKGYLSSHGIFLHAWRYTLRYAAGEAPEVLEAPPP------------------------------------
>UniRef50_Q38VQ0(53-197:239) Pseudouridine synthase n=6 Tax=Lactobacillus RepID=Q38VQ0_LACSS   E=2e-11 s/c=0.50 id=25% cov=56%
--PIRYQTNFYWLLNKPAGVIS--ATTDPQKTVMDLFAPADYR-EDLFPVGRLDKDTTGLLLITNDGDLAHDLLS--PKKHVAKTYRAKIAGVVT---------AADQAQFAAGLKLRDFDAQPAQ--LTILRTDTARQE---------SLIEVEIHEGKFHQVKRMFHAVG----------------------------------------------------------------------------------------
>UniRef50_A9BF27(38-182:220) Pseudouridine synthase n=1 Tax=Petrotoga mobilis SJ95 RepID=A9BF27_PETMO  E=8e-11 s/c=0.48 id=21% cov=53%
-------------LNKPKGILC--TFKDDFGRKTINDLIKGKIEERVFYVGRLDYDSSGLLLLTNDGDLANYLLR--PENKVTKVYEVLVKGSPS----------KKELQMLEEGITLETGYKTMKSKVKILKKQK-----------DLSLLQISLNEGKKRQIKLMIKALGYKVI------------------------------------------------------------------------------------
>UniRef50_B3U4L2(65-203:420) Pseudouridine synthase n=3 Tax=Bacteria RepID=B3U4L2_9BACT   E=1e-10 s/c=0.50 id=22% cov=53%
-----------LILNKPKN--VMSTLDDPEGRPTVKDLLH-GVTVRVFPVGRLDFDSEGLMLLTNHGDLAQAL--LHPRYHVPKTYLIKVKGVL-----------DDAKIEALERGVKLEDGFTAPAKVKKVSRAESN-----------SWLEVTIHEGRKHQVKRMVEAVGHSVI------------------------------------------------------------------------------------
>UniRef50_B2T6J8(2-152:189) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=B2T6J8_BURPP   E=2e-10 s/c=0.46 id=26% cov=58%
---------HLLALNKPFGTICQFSP--HETRASLADWVK---VPDVYPAGRLDSDSEGLLLLTDDGALQARIAE--PRHKLVKRYWAQVEGAVDAATLKKLARGVDLGDYVTRPCRAEYvEPTDA------LWTRTPPIRFRAAIPT--TWIELSITEGKNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_C5EVC9(101-235:294) Pseudouridine synthase n=6 Tax=Clostridiales RepID=C5EVC9_9FIRM   E=3e-10 s/c=0.50 id=25% cov=52%
----------LLVVNKPRGIVCTTSDKDRAMNIVEYL----DYPERIYPVGRLDKDSEGLLLMTNQGDLVNKIMRSGNAH--EKEYIV----------TVDRPLTDDAMDRMAKGI-----------YLRELETVTRPCKVKRVDGKTFSII---LTQGLNRQIRRMCEACGCHV-------------------------------------------------------------------------------------
>UniRef50_C6MZI4(54-203:240) Pseudouridine synthase n=1 Tax=Legionella drancourtii LLAP12 RepID=C6MZI4_9GAMM  E=4e-10 s/c=0.45 id=23% cov=55%
----------LILFNKPFAVVCQFTGEKHEHTLA-----EFIDKPDFYAAGRLDKNSEGLLLLTNDGALQHQLTH--PKFNKKKYYWVQVEGIPT---------AADLEPLKKGLVLKDITFLPAE-----VRCIEEPALWPRTPPVRFrqsiptSWLEIILREGKNHQVRRMTAAMGFP--------------------------------------------------------------------------------------
>UniRef50_O96270(119-301:338) Pseudouridine synthase, putative n=2 Tax=Plasmodium RepID=O96270_PLAF7  E=6e-10 s/c=0.37 id=21% cov=62%
-----------IVLHKPKGLLC--TSNDEKNRKSIYTLFPEEMLQkyRLVTVGRLDRNTSGVLLLTNDYAWVNKLTHPKYQR--IRTYRVHIEGPVKMNALKELargiYLEEDEKTQPKKIYNYKESREKSniddkkkkkmskmkkKTNPAFIEILREEKIKIKEDTKKITVLNISIKEGRNRQIRKMFQQINQPVI------------------------------------------------------------------------------------
>UniRef50_C6UMY1(13-205:235) Putative pseudouridine synthase n=1 Tax=Candidatus Hodgkinia cicadicola Dsem RepID=C6UMY1_HODCD  E=1e-09 s/c=0.34 id=25% cov=65%
----LYEDEQLVVVVKTKRLL--ACPVANGGASVVHALAACHAPTSLTPAHRLDVGTFGVLAVRKTQARRAHAQRQLSWRRALKMY-AHLASAIEAAASP--------------------------------ASFCVASLALAVGCNSVLAVVTRLVLGRTHQIR----ASQRRVWGDVTYATRclLFGAFRATHSALKRQSLSACTLQVGHPV------------------------------------------------
>UniRef50_A3LZQ0(15-246:265) Pseudouridylate synthase (Fragment) n=1 Tax=Pichia stipitis RepID=A3LZQ0_PICST  E=2e-09 s/c=0.28 id=19% cov=65%
-----------VVVNKPSGIQCSGFKNYAHHLLpqltkkfKALHPDRTLNASQFKLVHRLDKYVTGGLVVARDRKWAMKSSKSLsskgnSPDSIIRRYVGLLP-IPEDDSLKSGWITYDIQAPQKDYKGSTETRKvlsyKALTIFQILDELKLQPTKTQlsmypkiYSGKCIVPIILQLQTGRKNQLRDHtLQSFNTTLLNDD---------------------------------------------------------------------------------
>UniRef50_Q3AI58(19-171:230) Pseudouridine synthase n=5 Tax=Cyanobacteria RepID=Q3AI58_SYNSC   E=2e-09 s/c=0.43 id=24% cov=57%
-----------LLLNKPYGVLSQFTSEEGS----RWRCLSDFVDvPQVYAAGRLDADSEGLLILTSNGRLQQRLTDPRFGHW--RSYWAQVEGTPNTEQLQQLCDG---------VVVQGRRTLPAKARW--LQGQDLPQLPERTPQIRFraaiptNWLQLSLSEGRNRQVRRMTAAVGLP--------------------------------------------------------------------------------------
>UniRef50_A8SYF2(62-199:239) Pseudouridine synthase n=1 Tax=Coprococcus eutactus ATCC 27759 RepID=A8SYF2_9FIRM  E=2e-09 s/c=0.47 id=23% cov=32%
-------------LNKPAGCVS-ATKDNVHQT--VIDLLNGENTKDLFPVGRLDLDTEGLLIITNDGRLAHHLLS--PAHHIAKTYYADIDGYVDDQTI-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5V220(66-200:624) Pseudouridine synthase n=5 Tax=Bacteria RepID=A5V220_ROSS1   E=3e-09 s/c=0.48 id=25% cov=49%
-----------VMLHKPAGVVS--TTDDPQGRPTVIDLV--NLEQRLFPVGRLDYDSEGLLLLTDDGELTQKLTH--PSYQVEKEYRVLLNEAPSPAAL-----------RAWRTGVELDGVKTAPAWVELIER-----------TPDGAWVRVILHEGRKRQIR-----------------------------------------------------------------------------------------------
>UniRef50_Q2JQ37(35-179:226) Pseudouridine synthase n=10 Tax=Bacteria RepID=Q2JQ37_SYNJB   E=4e-09 s/c=0.44 id=25% cov=54%
---------------KPYGVLTQFTDREGRPTL-----QSFIPVPRVYPVGRLDRDSEGLLLLTDDGRLNARLIDPKFGH--ERIYWVQVEGIPTPQALQQLQQGLIIQGRKTRPAQV-----------KVLA--EEPTLPPRDPPIRFrrsiptTWLELTLREGRNRQVRRMTAAVGIP--------------------------------------------------------------------------------------
>UniRef50_C0FY58(85-220:261) Pseudouridine synthase n=3 Tax=Clostridiales RepID=C0FY58_9FIRM   E=5e-09 s/c=0.47 id=22% cov=50%
---------------KPAGCVT---ATEDQLHKTVMDYLTDTVRSDLFPVGRLDIDTEGLLLITNDGALAHDLLS--PAKHVEKTYYAVIDGVVTEKDVNSFENGVDIGE----------------------EKLTKPGKLRILKSEPESEIELTITEGRFHQVKRMFEAVG----------------------------------------------------------------------------------------
>UniRef50_Q24V73(81-217:257) Pseudouridine synthase n=3 Tax=Bacteria RepID=Q24V73_DESHY   E=6e-09 s/c=0.46 id=27% cov=53%
-------------LHKPTGYIT--SVTDPQGRKTVME-LMPKIPRRVYPVGRLDYDTSGLLLLTNDGDLAHRLMH--PSYGVEKTYRVEVGEKIPEQAL---------KRLEKGVLLEDGKTAPA--------RIREVSPKGRGSLPTY---EITIHEGRNRQVRRMFKAVGFPL-------------------------------------------------------------------------------------
>UniRef50_A3YG85(4-152:242) Pseudouridine synthase n=2 Tax=Gammaproteobacteria RepID=A3YG85_9GAMM  E=6e-09 s/c=0.43 id=25% cov=56%
----------IIVFNKPFQVLSQFTTDEEKATLSSFI-----DKANFYPAGRLDYDSEGLLLLT-DHGALQHLIAS-PQHKMPKTYLVQVEGELTKEAV---------EQLRVGVELKDGLTKPAEAK---IASDFEPWPRHPPIRERknipTSWLELTITEGKNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_A3JEU2(75-213:250) Pseudouridine synthase n=2 Tax=Marinobacter RepID=A3JEU2_9ALTE   E=1e-08 s/c=0.45 id=23% cov=52%
--------AHYIMLHKPAGYLS---ATEDDTHPTVLQLLPPGLSQCLHIAGRLDRATTGLMILTNNGTWSRQLT--LPGMGIAKVYRV----------TTAYPIGPDTPQ------------RFAEGIW--FEYEQLTTAPATLELLEPTLARLTIYEGRYHQVKRMFHAVG----------------------------------------------------------------------------------------
>UniRef50_Q01SF5(66-199:249) Pseudouridine synthase n=3 Tax=Bacteria RepID=Q01SF5_SOLUE   E=2e-08 s/c=0.46 id=25% cov=52%
-----------IALNKPKGTVT--TVHDPEGRETVMDLLH-RVKERVYPVGRLDYHSEGLLLLTNDGELANSIMSA--ATHLEKTYVVKVTGTLTAEQ---------EEKFRTGVPLSGRRTLPA--GLKLLSRAENP------------WYEVKLTEGRNNQIRMMFRHFG----------------------------------------------------------------------------------------
>UniRef50_D0MIA1(71-210:268) Pseudouridine synthase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MIA1_RHOM4  E=2e-08 s/c=0.44 id=25% cov=54%
-----------ILMNKPHDTITTCDDERGRRTVLDLINLPPEQKNGLFPVGRLDRNTTGVLLLTNDGELANRLMH--PRYRVEKIYVARTA----------RPVKPEEAEQLRRGVQLEDGPARAV-----------QVAVNPADPHEIALM---IYEGRNRQVRRMLEAIGHEVV------------------------------------------------------------------------------------
>UniRef50_C6W5I1(4-158:201) Pseudouridine synthase n=1 Tax=Dyadobacter fermentans DSM 18053 RepID=C6W5I1_DYAFD  E=2e-08 s/c=0.40 id=20% cov=57%
-------------IYKPFNMLSQFSREGDHQTLAD---LGFTFAKDIYPVGRLDADSEGLLLLTNDNFLKTKLLEPRNRHT--RTYYVQVEGEVTDEAC----------RQLSAGVSISINGKQYKTLPAEIAKIAEPELPERNPPIRFrkniptSWLSVTLREGKNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_Q4Z2R8(124-298:318) Pseudouridine synthetase, putative n=3 Tax=Plasmodium (Vinckeia) RepID=Q4Z2R8_PLABE  E=3e-08 s/c=0.35 id=21% cov=59%
-----------IVMHKPKGLIC--TNQDEKDRKSIFSIFPDDLLQKYRIvsVGRLDRNTSGVLLFTNEYTWVNKLTHPKYERV--RKYMIHIEGPVRMDALKMLAngvYLKDEDNNKKKKKKT----QPAF-----IEVLREENVKIQNQIKKITVLNISIKEGRNRQIRKMFQQINQPIV------------------------------------------------------------------------------------
>UniRef50_Q1QUR9(62-210:257) Ribosomal large subunit pseudouridine synthase E n=26 Tax=Bacteria RepID=Q1QUR9_CHRSD  E=5e-08 s/c=0.41 id=26% cov=55%
----------LYLLHKPYQMLSQFT--DTRGRATLAEAI---DVPDIYPAGRLDYDSEGLLLLTGDGALAHRISH--PRHKQPKTYWVQVEGEPEPAALQ---------ALRQGVTLRDGPTRPAK-----VRRLESPDVAPRHPPVRHreavptAWLELTLSEGRNRQVRRMTAHVGHP--------------------------------------------------------------------------------------
>UniRef50_B1XK09(5-158:223) Pseudouridine synthase n=1 Tax=Synechococcus sp. PCC 7002 RepID=B1XK09_SYNP2  E=6e-08 s/c=0.39 id=21% cov=58%
-----------VLLHKPYNVLCQFTDNSPQGSQ--RQTLKDFVPvPDIYSVGRLDLDSEGLLLLTNDAPLKHYLCEPKFAH--SRTYWV---------QVENIPDGQALEQLRQGVMVQGKKTRPAIANLLTPEptVPAREPPIRFRKNVPTAWLELTLTEGRNRQVRRMTAAVGHP--------------------------------------------------------------------------------------
>UniRef50_A3ZQL4(81-215:517) Pseudouridine synthase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A3ZQL4_9PLAN  E=1e-07 s/c=0.44 id=24% cov=52%
-------------LNKPPGVLS--TNFDPAGRTRVIDMV--PQDVRLFTIGRLDRASEGLIVVTNDGELANRLAH--PRYEIEKTYRVEVAGHPEPDAIT---FVRRGVHLAEGFVQP-------------------VSVVMKRKNKQSTTLEVILDEGKNREIRRLMAKIGHKVL------------------------------------------------------------------------------------
>UniRef50_Q1D9N8(86-225:268) Pseudouridine synthase n=4 Tax=Cystobacterineae RepID=Q1D9N8_MYXXD   E=1e-07 s/c=0.42 id=24% cov=52%
----------VLAFHKPAGLLSSTERQHRTGT--VFEALLPQLPPELagytwHAVGRLDVDSTGLLLFTNDDKLVAHATS--PDAHLPKRYVA---------TVFSTASDERVEPLRRGMTLDDGPARPAKVNVR----------------DEHT-VEVTLTEGRHHQVKRMLGAVGLPV-------------------------------------------------------------------------------------
>UniRef50_C6JI84(67-202:236) Pseudouridine synthase n=2 Tax=Fusobacterium RepID=C6JI84_FUSVA   E=2e-07 s/c=0.43 id=25% cov=53%
------------ILNKP--LEVLSSSKDDRGRKTVVDLINCK--ERIFPIGRLDYNTSGLIILTNDGELFNRIIH--PKAEIFKEYYVKVLGEIKEN---------NVELLKNGVELDDGITLPA--NVRILRR-----------EKGKTELLVAIREGRNRQVRRMMDKINHPVI------------------------------------------------------------------------------------
>UniRef50_B1XJP9(65-207:259) Pseudouridine synthase n=3 Tax=Chroococcales RepID=B1XJP9_SYNP2   E=3e-07 s/c=0.41 id=21% cov=53%
-------------IHKPKGVVS--TCADPKGRSTVLDLLPPPLrqGKGIHPIGRLDAQSTGALLLTNDGNFTLALTH--PRYHIPKTYRVWLKGKVPEHVLDQW---------RQGVMLGDRRTLPTQIHLKTI-------------TQDKTCIDIMLTEGRNRQIRRVAEQLGFPVV------------------------------------------------------------------------------------
>UniRef50_C1N350(62-203:230) Predicted protein (Fragment) n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N350_9CHLO  E=3e-07 s/c=0.41 id=21% cov=53%
---------------KPRGVTCTTDARDRTNIVDAV----NYPDARLFPVGRLDKDSTGLILLTSDGRLPNA--ALRSGRKRDKKYLVVVDAVVRPE---DVRMLRDGVVISTPVQRDRVD--------RVLTARTLPCEIDVVGART---LEITLREGRNRQIRRMLDAVGY---------------------------------------------------------------------------------------
>UniRef50_B9XS61(63-197:235) Pseudouridine synthase n=1 Tax=bacterium Ellin514 RepID=B9XS61_9BACT  E=4e-07 s/c=0.43 id=26% cov=50%
-----------VALNKPRGYVC--SRKDDRKRKVIGDLLPAEWD-NLYSVGRLDSDSEGLIFLTNDGEFSLHLTH--PRYRVLKKYLATVEGRVEQEMLQ-----------RFKHGIVHEGEKLKVDRARTLSV-----------QNSTSLVELELTEGKNREIRR----------------------------------------------------------------------------------------------
>UniRef50_Q1IR68(76-207:254) Pseudouridine synthase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=Q1IR68_ACIBL  E=5e-07 s/c=0.44 id=28% cov=22%
------------VVNKPRGLITTASDEKGRETI---YSLLPPDSPWVAPVGRLDKASEGLLLLTNDSEWAAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8ET33(75-214:255) Pseudouridine synthase n=29 Tax=Proteobacteria RepID=B8ET33_METSB   E=5e-07 s/c=0.41 id=29% cov=54%
----------VIALNKPRGVTCSRKEAGPLVFDLLPPRFRLREPA-LSTVGRLDKDTSGLLLITDDGALLHRLIS--PKHNIAKRYCAKLARPLRGDE------AEIFASGEMMLDDEAKPLLPAV--LRVLSPTEA---------------EVSVTEGRYHQIRRMFAATGNHVL------------------------------------------------------------------------------------
>UniRef50_Q4FV02(6-171:208) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=Q4FV02_PSYA2   E=5e-07 s/c=0.34 id=19% cov=60%
----------LILFNKPYGVQSQfRDDSNNDHTTLS----EYFTDKSLRIAGRLDATSEGLLILTSDGRINKAITQPPSAKNFaqnkqkqGKTYLVQVEGVVTAVQLKELAsgvILKDGKTLPASATLLDEADLP-ITLWQR------DPPIRERKNIPTSWLMLTIYEGKNRQVRRMTAHVGLPCL------------------------------------------------------------------------------------
>UniRef50_B8DUD9(82-241:257) Pseudouridine synthase n=8 Tax=Bifidobacterium RepID=B8DUD9_BIFA0   E=7e-07 s/c=0.35 id=22% cov=53%
-----------LALNKPRKVLS--TMDDPKGRYTLRDIVGDKY-ERIFHMGRLDYDSEGLILMTNDGELSQHVMH--PKYEVEKTYIATLEGH--MSGTVCRRLVRTGVQLDDGWIKLD--------HCSIIDS-----------NRDQTIVKVVLHSGRNRIVRRIFGAIGFPV-------------------------------------------------------------------------------------
>UniRef50_C6J9Y4(74-282:323) Pseudouridine synthase n=2 Tax=Clostridiales RepID=C6J9Y4_9FIRM   E=1e-06 s/c=0.27 id=21% cov=66%
----------LLLFNKPRGIVC--STKQQFDETTVTDYL--DYPLRVYPVGRLDKESQGLLLLTNEGDLVNKIMRAGNYH--EKEYFV----------TVNKPVDREFVRRMSKGVP-------------VLDTVTRPCRVVQTGECSF---RIILTQGLNRQIRRMCRYLG--------YEVQKLKRIRIMNLTLDGI------------REGEYREITAQEWEELNHLLE----------------------------
>UniRef50_B2UKZ1(57-200:230) Pseudouridine synthase n=1 Tax=Akkermansia muciniphila ATCC BAA-835 RepID=B2UKZ1_AKKM8  E=1e-06 s/c=0.39 id=25% cov=54%
------------ALYKPEGYTCSHDDGEGNLIYDLLPFQWRHRNPAVSSVGRLDKETSGLLLLTDDGKFIHRMTS--PRHHVAKVYEAVTEEDIPTEAV------ELFASGTLTLNGETRPCAPALLEIR---------------EPRRALL--TLTEGKYHQVRRMLAAVGAPVL------------------------------------------------------------------------------------
>UniRef50_B1ZYI5(2-153:188) Pseudouridine synthase n=2 Tax=Bacteria RepID=B1ZYI5_OPITP   E=1e-06 s/c=0.37 id=23% cov=58%
----------LCALHKPYGVLSQftPEPGSRWRTLA-----EFGLPPAVYPLGRLDADSEGLLLLSDEPGLNTRLLNPDQAHR--REYWVQVERVPTDAALAQLQRGVKIGDYATRPCAARRL-DPAPT----LPPRDPPIRARKNVPD--CWLALELIEGKNRQVRRMTAAIGHP--------------------------------------------------------------------------------------
>UniRef50_B5YJH7(66-202:237) Pseudouridine synthase n=1 Tax=Thermodesulfovibrio yellowstonii DSM 11347 RepID=B5YJH7_THEYD  E=2e-06 s/c=0.40 id=24% cov=53%
------------AFYKPRKVIT--ALLDPQGRPTIRDFIK-GIKFRIYPVGRLDFDSEGLLLLTNDGELA--YKVMHPSSQIEKTYMVKVDGIVEPETI---------EKLRKGIKIE---GKLAV----------PVSVHLVKKLKANSWIKITLHEGRKRQIRKMLERVGHPVI------------------------------------------------------------------------------------
>UniRef50_Q21EB0(66-198:249) Pseudouridine synthase n=14 Tax=Gammaproteobacteria RepID=Q21EB0_SACD2  E=3e-06 s/c=0.41 id=26% cov=50%
-----------IMLNKPAGRVS---ATKDSTHPTVVGCLPQQLQANIHIVGRLDFNSTGLMLLTNNGAWSRHLTS--PENKVNKIYEVELERTINDD---EWPQYISAFASGMYFAFEDLTTQPAK-----LERLTATRA-------RVTLVE-----GRYHQIKR----------------------------------------------------------------------------------------------
>UniRef50_C8PVP6(4-163:234) RNA pseudouridine synthase family protein n=1 Tax=Enhydrobacter aerosaccus SK60 RepID=C8PVP6_9GAMM  E=3e-06 s/c=0.34 id=22% cov=58%
----------LILFNKPYGVLSQFRSDDNNNFATLSDYFTDKS---LRVAGRLDATSEGLLLLTADGQVNKALthpPKANAGKQQGKTYWIQVEGDASDAQLQQL---------QTGVPLKDGITLPA----EVVRLSEAQIAEHIWQASDkiakrkvTTWLAITIFEGKNRQVRRMAAHVGLPCL------------------------------------------------------------------------------------
>UniRef50_A6GNL7(132-273:458) Pseudouridine synthase n=2 Tax=Betaproteobacteria RepID=A6GNL7_9BURK  E=3e-06 s/c=0.38 id=29% cov=24%
----------VLIYHKPAGEIV--SMDDPQGRTTVFQKLPKISNGKWIAVGRLDFNTEGLLLFTSSGELANRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0LG91(59-205:553) Pseudouridine synthase n=3 Tax=Bacteria RepID=D0LG91_HALO1   E=4e-06 s/c=0.37 id=31% cov=34%
----VYpEEPFYVLLNKPKGCLT--AVTDPENRPTVMEYLH-GLPARVVPVGRLDFYSEGVLLLTNDGDLSARL--QSPRHHVEKTYHVKVRDQVTE--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0SE82(57-195:244) Pseudouridine synthase n=1 Tax=Acinetobacter johnsonii SH046 RepID=D0SE82_ACIJO  E=4e-06 s/c=0.39 id=23% cov=25%
-----YREKVYIALNKPQGYeCSHQATHHFSVFDLFDDVLLNRG---IQCVGRLDQDTTGLLLLTDDGQFLQAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1AL84(43-197:233) Pseudouridine synthase n=1 Tax=Sebaldella termitidis ATCC 33386 RepID=D1AL84_SEBTE  E=5e-06 s/c=0.35 id=24% cov=25%
------EDNDFVAfdgkriefkeflyimLNKPQDVIS--ATDDERHRTVLDLLEEPLTKVGLFPVGRLDKDTEGLLVLTNDGKMAHEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5INL2(16-167:243) Ribosomal large subunit pseudouridine synthase E n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5INL2_9CHRO  E=6e-06 s/c=0.35 id=24% cov=57%
-----------LLFHKPYGVLSQftPEPGSRWRCLADFIAV-----PGVYAAGRLDADSEGLLLLTANGRLQQRLTDpAFGHW---RTYWVQVEGEAGQRPEA-------LQQLRQGVVIQGRLTRPAL--VRCLSDPKLPERDPpirQRATIPVSWLELQLQEGRNRQVRRMTARVGLP--------------------------------------------------------------------------------------
>UniRef50_A8ZRV1(72-204:241) Pseudouridine synthase n=3 Tax=Desulfobacteraceae RepID=A8ZRV1_DESOH  E=7e-06 s/c=0.40 id=36% cov=23%
-----------IALNKPPGYVT--SCLQKQETTVMELVA---VDQRVFPVGRLDKPSCGLLLMTSDGGLHQRLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6F9V5(61-200:239) Pseudouridine synthase n=17 Tax=Acinetobacter RepID=Q6F9V5_ACIAD   E=2e-05 s/c=0.37 id=25% cov=22%
----VYREKVYIILNKPKGFeCSHQPHHHQSVFSLLPDLL---IQRNIAAVGRLDQDTTGLLLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q00UF3(334-428:428) Chromosome 16 contig 1, DNA sequence n=1 Tax=Ostreococcus tauri RepID=Q00UF3_OSTTA  E=4e-05 s/c=0.54 id=26% cov=35%
---------------------------------------------RVWAVNRLDAPVSGVWLCATSVKASLKAREWLsKPGTSTKTYLARVSKgsaltTPDGGLRIDAPLWKNAKTSVAELRPESEGGKPCATRIFLLEQ------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6EPE0(51-224:291) Pseudouridine synthase n=1 Tax=unidentified eubacterium SCB49 RepID=A6EPE0_9BACT  E=5e-05 s/c=0.29 id=28% cov=20%
------ENNNLvyIILNKPVGITCTTDLRVEGNVVDYIDH-----KERIFHVGRLDKPSEGLLLM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7PFL3(67-200:389) Pseudouridine synthase n=3 Tax=Bacteria RepID=C7PFL3_CHIPD   E=8e-05 s/c=0.37 id=19% cov=52%
-----------LALNKPPGITTTTELHIKDNIISFV-----NYPQRIFPIGRLDKDSEGLIFLTNDGDIINKILRAANNH--EKEYVVRV----------NKPIDTNFLHQMSQGVP-------------ILDTRTLPCKVQMTGRQTF---RITLTQGLNRQIRRMCEYLGYTVVG-----------------------------------------------------------------------------------
>UniRef50_C6XQT2(98-175:508) Pseudouridine synthase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XQT2_HIRBI  E=0.0001 s/c=0.63 id=30% cov=22%
--------------HKPKGLVT--TNSDPEGRPTVFEHLPKKL-PRVMTIGRLDLNTEGLLLLTNDGELARTL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4AAG8(66-134:240) Pseudouridine synthase n=6 Tax=Mycoplasma RepID=Q4AAG8_MYCHJ   E=0.0002 s/c=0.71 id=24% cov=27%
------------ALNKPKNYIT--SRFDPENRPTIMEFFSK--NEYLFPVGRLDFQTTGLILITNDGKTTNKL--LHPSSKIERTYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1BMI6(41-194:232) Pseudouridine synthase n=3 Tax=Veillonella RepID=D1BMI6_VEIPT   E=0.0002 s/c=0.32 id=35% cov=22%
-IDI---DVDIVAVDgkvvsttqlyyvkfhKPKGYVT---AVEDSNHPVVMDLLpPEFIKMGVVPVGRLDKDTEGLLLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4BXB5(2-152:181) Pseudouridine synthase n=2 Tax=Bacteroidetes RepID=A4BXB5_9FLAO   E=0.0002 s/c=0.32 id=19% cov=57%
-------------VHKPWGMISQFVNPAKRKKTLLGDLY--GFPEGTMAIGRLDVPSEGLLLLTTDGKVSAE----IRSNAYEKEYYVQVDGIMTAAALENLKTGVEIGFKGTKYVTKPGKAM-------LLKDPRFPLRSQKIRDERHgptSWISIIIKEGKFRQVRKMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_B8BQ39(161-334:370) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BQ39_THAPS  E=0.0002 s/c=0.28 id=21% cov=47%
-----------------------------------------------HPVGRLDYDTTGLILFSSDGKLTQRL--LHPRRGVEKEYVAtvqgevnaselremLANGVETTDGTFAANLIAVTSSNGPSEVSEEDLN-------NVPEEDEGGDETTDEPyNGPYSDVRLVVSEGKYRMVRRILANSGHPVV------------------------------------------------------------------------------------
>UniRef50_B8KTF1(149-291:311) Pseudouridine synthase n=1 Tax=gamma proteobacterium NOR51-B RepID=B8KTF1_9GAMM  E=0.0002 s/c=0.34 id=22% cov=24%
---------HYIMLNKPSGVVC-ATRDARHRT--VIDILDLPFQHTLHIVGRLDIQSTGLVLLTNDGQWSRRLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q54RS0(68-205:571) Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum RepID=Q54RS0_DICDI  E=0.0003 s/c=0.35 id=21% cov=52%
-----------IAVHKPSGYIC--STVNDHDHKIIYDILPKeffKRKPTLSIAGRLDKWVTGLVVLSQDGKLVDRIISP-KDDGCGKDYEVVLKDKLVGDE------AEVFESGKIMLRGESTPCKPA--KLQVLDKEKNK-------------VKVTLYEGRYHQIRRMFAS------------------------------------------------------------------------------------------
>UniRef50_C6UMX9(18-133:167) Putative RNA pseudouridine synthase n=1 Tax=Candidatus Hodgkinia cicadicola Dsem RepID=C6UMX9_HODCD  E=0.0005 s/c=0.41 id=28% cov=45%
----------VLVVNKWAG---------AAHTSVVRQL------SCFVPAHRIDALTSGLLVLERKLARLRLSLRRK-------TYLCLSHDAFAACARC----------RVTTWIRRRSAWKCCVSYVACLEAV-----------SGLALLGVTLVTGRNRQLRRQLA-------------------------------------------------------------------------------------------
>UniRef50_Q605S3(19-164:231) Pseudouridine synthase n=1 Tax=Methylococcus capsulatus RepID=Q605S3_METCA  E=0.0006 s/c=0.32 id=23% cov=28%
----------VLLYHKPVGELV--SRRDPEGRPLIFSRLPRLELGRWVAVGRLDVNTQGLILLTNNGELAHRLMH--PSHAVEREY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3QB38(4-152:182) Pseudouridine synthase n=4 Tax=Bacteria RepID=A3QB38_SHELP   E=0.0008 s/c=0.31 id=20% cov=57%
---------------KPYGYLSQFVGERRKRKPLLGELANFPTG--IMAIGRLDHDSEGLLLLTTDGKT----SHAVRSKSIEKEYYLQLDGEITEQAISSLCEGVEIGIKGEKYRTLPCRAR------RLDQAPDLPPRGRKIRDARHgptSWLAITITEGKNRQLRKMTAAVGF---------------------------------------------------------------------------------------
>UniRef50_Q45826(91-313:316) Uncharacterized RNA pseudouridine synthase Caur_0901 n=5 Tax=Chloroflexi (class) RepID=Y901_CHLAA  E=2e-63 s/c=1.09 id=35% cov=83%
-LDVVYEDADIAVINKPAGMVVHPAPGHPRGTLVNALLARYpdlaiGGELRPGIVHRLDRDTSGLLVIARHDQAMRSLVDQQQARRMRKIYQALVIGRPPETGTIDAPIGRDPRDRLRMAVVPD--GRPARTHYRLLDTF-----------GDYSLLEVQLETGRTHQIRVHLRHLGYPIVGDPVYGPRRS------HLHLSRQFLHAAYLGLVHPRSGRWQEFTAPLPADLQIVLRQL--------------------------
>UniRef50_Q82WZ5(109-331:344) Ribosomal large subunit pseudouridine synthase D n=2 Tax=Nitrosomonas RepID=RLUD_NITEU  E=2e-62 s/c=1.08 id=32% cov=84%
-LKILFEDDHLIIIDKPAGLVVHPGNGNWHGTLLNALLNHAPqlsQVPRAGIVHRLDKDTTGLLVVAKTIEAQFDLARQLQQRTVKRHYLALVLGKLEKDGVVDAPIGRHPIHRTRMAVV--QNGKPARTHYRVLEKFTAS-----------TLLHCSLETGRTHQIRVHLLSIGHPLAGDPVYGRTSPDPSTADAvVRLPRQALHAWQLELTHPHSGQILLWESPLPDDMAALLQ----------------------------
>UniRef50_A7HV45(226-472:482) Pseudouridine synthase n=56 Tax=Alphaproteobacteria RepID=A7HV45_PARL1  E=1e-59 s/c=0.94 id=30% cov=85%
-LEIVYEDADLIVVMKPAGLVVHPAPGNPDMTLVNALVAHCgetlsgiGGEKRPGIVHRLDKETSGLMVVAKTDRAHQGLSAQFAAHgrdgKLTRAYTALTWGVPqTRKGTVDANIARSSHNRSKMATVRDRgeetGGRIAITHYTV---------KTDYADGLVAEVECRLETGRTHQIRVHMTALGHPLLGDATYGTGMKSRKsklspeaQAALERLNRQALHAHHLGFEHPVAGEKMSFDAPLPEDMQEL------------------------------
>UniRef50_D1ANU4(77-299:305) Pseudouridine synthase n=14 Tax=Fusobacteriaceae RepID=D1ANU4_SEBTE   E=1e-59 s/c=1.04 id=30% cov=83%
-IKILYEDSDIAVIDKEAGIVVHPSHGHESGTLVNAVMYHIKdlsginGEIRPGIVHRLDKDTSGLLIIAKNDTAHLRLSEMFGSSGIRKTYIAILKGKINKESGKLETLIGRDPKDRKKMAVVKTNGKTAITYFQVLDKNE-----------KFSLVKVNIQTGRTHQIRVHMKYLGYPVLGDSVYG--------RDNKIAGRQMLHAYKLEFLHPVTQKAMKIISELPQDFEKALKETG-------------------------
>UniRef50_C6WV38(90-319:368) Pseudouridine synthase n=3 Tax=Proteobacteria RepID=C6WV38_METML   E=3e-59 s/c=1.00 id=30% cov=84%
-LDIVYEDDHILVVNKPAGMVVHPAAGNWDGTLLNALLFHApqlHDVPRAGIVHRLDKETSGLLVVAKTLNAQTHLVRQLQARTVKREYRAIVWGQLWRNGVVDQPLGRDPRSRTKMAIN--RMGKPAITRYEILERFSVQ-----------TYLRCNLETGRTHQIRVHMQHLKAPLVGDPVYGFRGIVPIRAMTQTLrdavsqfHRQALHAIKLGLVHPATNEFMEWQIELADDMKVLLE----------------------------
>UniRef50_A0L9J0(87-327:332) Pseudouridine synthase n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L9J0_MAGSM  E=4e-59 s/c=0.95 id=30% cov=85%
-LEILFEDEHLIVLNKPAGMVVHPGAGVNHGTLVNALLYHCGTPDNPHgglsgiggvirpgIVHRLDKETSGIMVAAKQDHAHIHLSRQFEQRTIGRRYLALTRGIPqPAQGRIEGAIGRHPIHRTKMAVVE-QGGRAAATRYKVLE-----------PLGQFALIRCRLESGRTHQIRVHMTHIGHPLVGDPLYGAQHKAPSHWPPLHrqrfdqFQRQALHAHTLTFIHPHTGEEMSFKRPPPADFRQLYETL--------------------------
>UniRef50_B8E0R4(79-299:303) Pseudouridine synthase n=1 Tax=Dictyoglomus turgidum DSM 6724 RepID=B8E0R4_DICTD  E=4e-59 s/c=1.04 id=28% cov=82%
-IEIVYEDEDMVIINKPKGMVVHPAHGHYNDTLVNALLYRvkdlsgIGGELRPGIIHRLDKDTTGLLIIAKNDLSHQKLSEQLKNRTLRRTYWALCEGEIPWeEKRIEAPIGRHPINRKKMAIV--PYGKIAITNFKVLERFK-----------GYTLISADLETGRTHQIRVHISHLGFPIVGDEVYGRID------KKFGVKGQLLHAKKVSFIHPTKGIPMEFEIDLPEEFKKVL-----------------------------
>UniRef50_C5VRN0(83-299:302) Pseudouridine synthase n=1 Tax=Clostridium botulinum D str. 1873 RepID=C5VRN0_CLOBO  E=1e-57 s/c=1.04 id=29% cov=82%
-LDIIYEDNDIIVVNKPKGIVVHPTKRHLNGTLSNGVLYYFNDKNEnsiVRLVNRLDMDTSGLVLIAKNAYSHMALSRDMQKDDFVKKYLAIVHGNFNEDsGVIDKPIYRVGEGTLKRII--DERGQRSITLFKVIEQYK-----------NASLVELTLETGRTHQIRVHLSSIGHPIYGDSLYGEEEPQY-------IDRQALHAYKLQIPHPKDGKILKLESSLPEDMKNLIRKL--------------------------
>UniRef50_UPI0001AEC02F(42-274:279) pseudouridylate synthase, 23S RNA-specific n=1 Tax=Alteromonas macleodii ATCC 27126 RepID=UPI0001AEC02F  E=3e-57 s/c=0.96 id=50% cov=90%
-LPVLYQDEHIIAIEKPPGLLVHRSPIDRHETVFAVQTLRDQIGQHVYPAHRLDRPTSGVLVFSFSSEIAAKLGQQMMDKQVVKTYHAIVRGFVHHTGYIDYALKYRYDKIADKHKRPQQPPQPASTMYQSVAKFEVPEPVGKYQSARYSLVKLSPSTGRKHQLRRHMVHIRHPIIGDTTHGDGKQNKFAKQHFNFNNLALSCTQMGFSHPVTGKWVSINSQMHSEMRLWLEKL--------------------------
>UniRef50_D1N7N8(83-316:323) Pseudouridine synthase, RluA family n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N7N8_9BACT  E=7e-57 s/c=0.95 id=30% cov=86%
-FPILYEDDVMLVIDKPAGVVVHPAAGNPTGTVVNALLGRYPQlaeqlactTSRPGIVHRLDKDTSGCLAVAKTANAQFKLSTAFAGRETRKTYLAITRGVPIRRSGELSTLIGRHPVSRQKMAVVERNGKLAITRYRV-------EYTGMLDGVEIGVLAVRILTGRTHQIRVHLASLGVPVLGDAVYGGAR-----TAVAGVERQLLHAWKLCVPHPATGTPMEFTAPPPEDIRRILERIG-------------------------
>UniRef50_UPI00016C3FBA(109-353:354) ribosomal large subunit pseudouridine synthase n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C3FBA  E=9e-57 s/c=0.91 id=31% cov=86%
-LDILYQDEWLALVNKPADMVVHPAKGNWSGTLVNALQWHFRehlstgaGHLRAGIVHRLDKDTSGVILVAKDDLTHRDLAMQFESRKVFKEYVAIAAGELERDsDYIEGALKMHPYDRLKMIVSTDPDAKHALSYYEVLERFR-----------GFTLVKVQPRTGRTHQIRVHLLHVGCAVLADKIYGGRAQvklseiapgTPPAEDEVLLGRQALHAFRLRFQHPRTGQWIEAEAPLPPDMRRTLDAL--------------------------
>UniRef50_C8PZW5(1-266:266) Pseudouridine synthase n=1 Tax=Enhydrobacter aerosaccus SK60 RepID=C8PZW5_9GAMM  E=1e-56 s/c=0.83 id=56% cov=91%
MLEILYQDEHCVAVNKPAGMLVHRSWLDRHETEFVMQTLRDQLAQYVYPIHRLDRPTSGVLLFALSSESARQLCEQFENRQVQKSYLAIVRGYLTvnaqTSGLIDYPLTQILDKIGdkpslqalqqRKVSSTDMFAealsspaeltllQPAQTHWQCLATTEQPfQARARYPTSRFSLARLTPITGRKHQLRRHMKHVFHPIIGDTSYGDHHQNRAIRQHIGVHRLMLHAHTLAFNRLTDNRRVDITAPVDTDWLTMCAQFGF------------------------
>UniRef50_D1PCC3(131-385:387) Pseudouridine synthase n=1 Tax=Prevotella copri DSM 18205 RepID=D1PCC3_9BACT  E=1e-56 s/c=0.87 id=27% cov=91%
-INVVYEDDQLMVVNKEAGMVVHPGAGNFHGTLiqAVAWHLRDMPefdanDPEVGLVHRIDKDTSGLLVVAKTPTAKNALGKQFFNKTTHRSYNALVWGnIVEDEGRIEGNIGRDPKNRLRMKVfdPDSGIGKTAVTHYKVLERF-----------GYTTLVQCVLETGRTHQIRAHMKHIGHPLFMDETYGGTEILRGQRSSsykafiqncfKLCPRQALHAKTLGFVHPTTKQQMDFDSEWPNDFRQLIEK--WRGFIAGTTQDTFK-----------
>UniRef50_C1SM47(81-297:302) Pseudouridine synthase n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SM47_9BACT  E=3e-56 s/c=1.01 id=28% cov=82%
-IEIIYDCDEFAVINKPAGITVHPAPGHADDTIVNAMLAEfditDDNDLRPGIVHRLDKDTSGLMIVAKNRKSREVLSKVFADRDIDKRYLAVCWGKPKElEFTIEQPIGRHYKDRKRMCVRED--GRYSKSGVRVLKQ-----------NNNAFLAEIRIFTGRTHQIRVHMSHAGFPLAGDVVYGHRQSLK-----LPIKRQALHSFRLAFVSPFTGEDMVFESPLPLDMKELI-----------------------------
>UniRef50_C0ZH07(81-296:306) Pseudouridine synthase n=1 Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZH07_BREBN  E=4e-56 s/c=1.02 id=31% cov=82%
-LSIRYEDEDLMVIAKPAGLVVHPTGNHPSGTLANgmiAYWKKRGENRKFRAVNRLDKDTSGLMIVAKNQWAHEQFSRMQQIRTLQRTYRAIVQGIVEsDDGTINTPIGLAENSFITRQVRPD--GQTAVTHYRVLARGE-----------GMSFVEVKLETGRTHQIRVHMSSEGHPLAGDDLYGGEREH--------IGRQALHAWGLSFVHPRSGLAMSWEEPLPNDMEQLAQQF--------------------------
>UniRef50_A8ZXZ8(82-317:329) Pseudouridine synthase n=1 Tax=Desulfococcus oleovorans Hxd3 RepID=A8ZXZ8_DESOH  E=4e-56 s/c=0.93 id=31% cov=85%
-LPLLFEDAFLLVVNKPPGLVVHPAPGHEGGTLVNRLLHHFpaigtvGEPDRPGIVHRLDRNTSGALVVAKTAAAHQALSDMFKSRQVRKTYLALVYGQMKSTGGVVTLPIGRHSLERKKMSVSSPQARPAETRWKV-----------RKAFVDASLLELEIHTGRTHQIRVHCTALQRPVVGDPTYPCkwtrKRQHFSSRASFELlnaaGRQMLHAWRLEFDHPVTGAPMCFTAPLFEDIKEML-----------------------------
>UniRef50_B7GAM3(73-300:325) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7GAM3_PHATR  E=5e-56 s/c=0.96 id=30% cov=86%
-LDIIFEDEHMIVINKAANMVVHPAAGNWDGTVVNALAYYlanrsESISFRPGIVHRLDKGTTGVLVVAKTSQTLATLSNFFAARQVKKTYMAITVGNPGKHVVIDKPIGRHPLHRQRMRVVPDPHQKNS-TGRRALSYVDTLAF-----DGKLSLVQVRIETGRTHQIRVHLQDRHTPIYGDDIYGLADWNKKLSKTHRIVRPLLHAYKLEINHPVTGEPMVFKASLADDMKR-------------------------------
>UniRef50_A1AW00(79-308:314) Pseudouridine synthase n=2 Tax=sulfur-oxidizing symbionts RepID=A1AW00_RUTMC  E=2e-55 s/c=0.94 id=28% cov=85%
VIDVVYEDEAIIIVNKPVNLVTHPGVSNWTGTLANALLHYDSSLANLdraGIVHRLDKNTSGLMVVARSEYAQKYLTRQLQTHSISREYSAIVYGHMISGGTVDKPIGRDPKDRIRQTVTES--GKDALTHYRVIERF-----------AHHTHVKVMLETGRTHQIRVHLSFIGHPLIADPMYGGKIRFPKKADKqlknslKNFNRQTLHAKKLTLIHPTSTELMSWKVPLPQDMQDLLQ----------------------------
>UniRef50_C7LWM1(82-303:526) Pseudouridine synthase, RluA family n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LWM1_DESBD  E=3e-55 s/c=0.98 id=32% cov=84%
-LNVFFADEDLVVVNKTPAMTVHPAPSVAEPTLVHRVAHHFpallsQSGERPGIVHRLDKDTSGLIVLALSESARLSLTQAFASREVYKEYLALVAGVPDSSGTVSLALGRHP-SIKTRMAVVERGGRAAETRFELLWSAADRSA---------SLVRVRIMTGRTHQIRVHMAALGHPLLGDAVYADKQTAA------RAPRQMLHAWQLRFEHPRSFESMEFCAPPPDDFLQVLREL--------------------------
>UniRef50_C6XNC0(98-357:369) Pseudouridine synthase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XNC0_HIRBI  E=4e-55 s/c=0.83 id=28% cov=87%
-LDVLFEDEHLIILNKPAGLVVHPAPGSTSGTLVNALLHHCagqlpgiGGVARPGIVHRLDKDTSGVMVAAKTEFAHTGLSSLFQAHFMERAYLAVTRGAPrPLLGKIETRIARSTTDRKKMAVVResrlsasaewhgeseedyEQKGKHAITNYKVLEQFGRIDATSGLPA--ATLTECRLETGRTHQIRVHMAHIGAPLLGDQTYGRYRGLKAHGSGPafetathackEFKRQALHAAILGFEHPVTGENLRFEVEPPEDM---------------------------------
>UniRef50_A9IIW7(101-324:324) Pseudouridine synthase n=5 Tax=Bordetella RepID=A9IIW7_BORPD   E=9e-55 s/c=0.96 id=29% cov=85%
---VVAESPDWIVVDKPAGLVTHPGAGNWSGTLLNGLLHRYPELARVaraGIVHRLDKDTSGLMVVARNELAQTHLVRQLQARSMGREYIALAHGWLPVAGKVDRPIGRDARVPVRMSVERPIAPKPAITHYAPLRR-------GRAPDGPVTEVACRLETGRTHQIRVHLASLGHPLLADTLYGG-------RLTAGATRQMLHARALHFDDPGGGGPAAFRADPPDDMRQVQEALQW------------------------
>UniRef50_A1U2H1(8-236:245) Pseudouridine synthase n=1 Tax=Marinobacter aquaeolei VT8 RepID=A1U2H1_MARAV  E=6e-54 s/c=0.93 id=51% cov=88%
----IYRDDWLLAVHKPAGLLVHRSPIDKHETEFALQYARAmNGGEHVYPVHRLDRPTSGVLLFARDPETARALGLAMMAGAVSKTYLAMVRGWAPEQGVIDHPLREEPEDRRLKGQ--EQPVREALTRYRRLATTELPVAIERYPTSRYSLVELKPETGRKHQLRRHMKHINHPIIGDANHGRGRHNRYFAERFGQGRLMLAATELRLRHPVTDEPLCLKAHPESSFLQVLAIF--------------------------
>UniRef50_B0K860(74-285:285) Pseudouridine synthase n=11 Tax=Thermoanaerobacterales RepID=B0K860_THEP3  E=9e-54 s/c=1.00 id=28% cov=81%
-LDICYEDEEILIVNKPANMVVHPTKRYQSGTLangVAWYFKEKGLKALIRPVNRLDRGTSGLVVFAKRPFMQYYLQ---IIKPMTKLYFAVVEGKMEGEGRIDLPISRKPQSGIERMVSEE--GDRAITNYKVVKSSK-----------RFSLLKVKIETGRTHQIRVHLSHIGHPIVGDTLYGSSDDY--------IKRQALHAYRLTFVHPLEEKSISVYSPLPQDIQNLLKLF--------------------------
>UniRef50_Q3JQ55(243-470:477) Pseudouridine synthase n=170 Tax=cellular organisms RepID=Q3JQ55_BURP1  E=2e-53 s/c=0.93 id=36% cov=85%
-FEILFEDDAIIVLNKPAGVAVHGGSGVAFGVIEQMRHARPH-AKFLELAHRLDRETSGILMLAKKRSALVGLHEQIRENRMDKRYFACVHGDWAADWGRRrvvkAPLFKYATPDGERRVRVQEDGLPSHTVFNLVDRW-----------PDYALVEAELKTGRTHQIRVHLAHLGLPIVGDAKYGDFALNKALARAnavPSIKRMFLHAHRLRLAHPLTGEPLQFDAPLPAECRQFIDQL--------------------------
>UniRef50_B5JL25(14-241:249) Pseudouridine synthase n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JL25_9BACT  E=4e-53 s/c=0.92 id=52% cov=88%
-LEILYRDERLVAIHKPSGLLVHRSPIDRRETRFAIQLLRDQIGQHVYPAHRIDRPTSGILLFGLDEAAGTALSLLFQNREIQKNYLAVTRGHLPESGLIDSPLHKYEDADGH---IKSSETQEAETAYRRLATTELPYPTERYDTTRYSLVELTPHTGRRHQIRRHLAHIRHPIIGDVRHGCNKANKLARSHFAIHRLLLAATHVVFVHPFTNAPLKIHCPPETSFQTALQ----------------------------
>UniRef50_P44433(99-318:322) Ribosomal large subunit pseudouridine synthase C n=22 Tax=Gammaproteobacteria RepID=RLUC_HAEIN  E=2e-52 s/c=0.95 id=33% cov=84%
---ILFEDDCLIILNKPSGIAVHGGSGLNFGVIEALRALRPE-ARFLELVHRLDRDTSGILLIAKKRSALRNLHEQLRVKTVQKDYLALVRGqWQSHIKVIQASLLKNELSSGERIVRVSEQGKPSETRFSIEERYI-----------NATLVKASPVTGRTHQIRVHTQYAGHPIALDDKYGDKDFDKQMNE-LGLNRLFLHAFSIRFEHPKNGETLRFNASLDHQMKAILQKL--------------------------
>UniRef50_B6J6C4(89-317:327) Pseudouridine synthase n=7 Tax=Coxiella burnetii RepID=B6J6C4_COXB1   E=2e-52 s/c=0.90 id=29% cov=84%
-LDVIYEDETLLVINKPVGLIVHPGAGVRDQTLINALLHYDPSlsvVPRAGIIHRLDKDTSGLLLIARTLASHHALIKAMKARQIVREYEAIVKGVLISGRTIEAPVGRHPIHRTRMAVV--EFGRPAITHFRIIKRYRA-----------HTHIRVQLETGRTHQIRVHMAHIHHPLAGDPVYGSHVgipvhlSDPLQTALKTLKRQALHGATLQFSHPVDQRPMACHAPLPADMAHLLE----------------------------
>UniRef50_Q1Q689(91-330:335) Similar to ribosomal large subunit pseudouridine synthase D n=1 Tax=Candidatus Kuenenia stuttgartiensis RepID=Q1Q689_9BACT  E=9e-52 s/c=0.85 id=28% cov=82%
-LNIIYEDDYLMLINKPYDMVVHPAGGHPSGTLVNAvtfycqNLSQINGPLKAGIVHRLDRDTSGVMLVIKSDAVHSHIAMQFEKRLVKKEYFAVVEGEVAFDsNEINMPIGRHRVDRQKMAVRRD-TGKNATSVYEVIERFR-----------GYTLVKIMPKTGRTHQIRVHMQAIGHPVVADEMYSKYNacfrsdllgKERAPDEGSIIERQALHAHRIEFFHPILNKQMAFQVDMAED----------------------------------
>UniRef50_Q1QTG8(5-258:261) Pseudouridine synthase n=2 Tax=Gammaproteobacteria RepID=Q1QTG8_CHRSD  E=1e-51 s/c=0.81 id=45% cov=97%
-LPVLYQDERMVAVQKPSGMLVHRSPIARDARVFALQTLRNQLGRHVYPVHRLDRPTSGLLLFALDPEMAQALGEEFTAHRVHKRYLAVVRGVGPEQDLLDYGLREEDGSRPKAEMPELE----AWTAVRRLDSVELPVRIDRYPQVRYSLMEARPWTGRRHQIRRHLARRGYPIIGDAKHGKGAHNRFFRERLDSPRLLLAAVGMTVWHPEQARTLQLDAPLADDMQALFARFGWQGHAPAARvawHAERPAALLSPG----
>UniRef50_C0E4Q3(83-306:310) Pseudouridine synthase n=2 Tax=Corynebacterium matruchotii RepID=C0E4Q3_9CORY  E=7e-51 s/c=0.91 id=31% cov=83%
-LEILYADEDLIAVDKPVGVAAHPTVGWDGPTVVGGLAAAgyristSGPPERNGIVQRLDVGTSGVMVVAASERGYSVLKRAFKERTVSKTYHALVQGHMdPLAGTIEANIGRHPSSGWKFAVTSD--GKHAVTHYETLEAFVA-----------ASLLEVHLETGRTHQIRVHMSALHHPCCGDPMYG---ADPQLSARLGLNRQWLHAVKLGFYHPADGRWLEIESPYPPDLRHALE----------------------------
>UniRef50_C0EHV8(80-294:299) Putative uncharacterized protein n=1 Tax=Clostridium methylpentosum DSM 5476 RepID=C0EHV8_9CLOT  E=1e-50 s/c=0.94 id=29% cov=82%
-FDIAYEDDDLLLVNKPAGTPVHPSPGHYEDSLANYSAWQYAQRREqlvFRPVNRLDRGTSGLLCVAKNAHAQARLSQQLHTGAFERIYYAVVCGAPsPAAGTIDLPIGRTPGSVLKR--RVDPQGARAVTHYETVRV-----------NGAYTLLKIRLETGRTHQIRVHFAHLGCPLFGDFLYGTERRDV-------VEGHALHSGEIRLLHPISGEEIRCSVPLPAYMENLMD----------------------------
>UniRef50_B7HGW1(84-296:297) Pseudouridine synthase n=52 Tax=Bacillales RepID=B7HGW1_BACC4   E=1e-50 s/c=0.95 id=31% cov=80%
---IIYEDDAVLIINKEANMSTIPSREHPAGSVANALLSHYdkqHLASTVHIVTRLDRDTSGLMLIAKNRFVHHLLSKQHQQKAVKRTYEAIVHGKiVEREGMIDAPIGRKSDSIIERTVCED--GQRAVTHFKVIDSTYHK-----------THVALELETGRTHQIRVHMAHVGHPLLGDSLYGGRRDE--------MKRQALHSKSLTFYHPILEKEMSFTIKLPSDMQEVL-----------------------------
>UniRef50_A3ZV48(39-277:281) Pseudouridine synthase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A3ZV48_9PLAN  E=2e-50 s/c=0.84 id=29% cov=83%
-LDIIYQDDRIAVINKPAGMITHPAKGHWKGTLTEGLKGQFpqlstiGGPTRPGIVHRLDRDTSGVIVIAKDDAAHEFLKTQFQDRLTEKEYFAMVIGAPDRDRdLINEPVGPHPKiRERMAIRRGDDEGKDAQTFYEVLERYQ-----------GFAAIKALPKTGRTHQIRVHLMHAGHPVLCDPLYGSRRFlslgelQHDDDRTVLLNRTALHAHRIAIAHPDDGEIREFIAPLPADL---------------------------------
>UniRef50_O31613(66-279:283) Uncharacterized RNA pseudouridine synthase yjbO n=53 Tax=Bacillaceae RepID=YJBO_BACSU  E=3e-50 s/c=0.93 id=31% cov=81%
-LDILYEDEHVLVINKQPYVSSIPSREHPSGSIANGiidHYQTTGVRATVHLVTRLDRDTSGIMLVAKHRFAHSILSSAQKNGLVKRRYAAVVHGRMAqMEGTVDAPIGRHPDSIIERTVTPD--GQKAVTHFYV-----------TCANDDMTSVALQLETGRTHQIRVHMSYLGHPLCGDTLYGGTRQE--------IGRQALHSEHLSFIHPLTQENMRFHAPLPQDMSKLIK----------------------------
>UniRef50_Q38W13(79-292:300) Pseudouridine synthase n=4 Tax=Lactobacillus RepID=Q38W13_LACSS   E=3e-50 s/c=0.93 id=30% cov=81%
-IKVLYEDDYWLVVNKPAGLATIPGPTNTTDTLLNrikgYWQQNGATDLVPHIITRLDFDTSGIVLAAKHQVAQSLLQPQIEQHQLQKFYLAVVAGTgLPEFGTIKAPIGRVGVEPRRRVI---ADGQSAWTDYWRLAQDE-----------RLTVLKVQIHTGRTHQIRVHLSDLDHPLVGDQLYEGPLGW-------GIDRQALHAYQLTFNDPFSQQKRQFTAPIPADIQAIL-----------------------------
>UniRef50_A3Y8C6(99-316:322) Pseudouridine synthase n=1 Tax=Marinomonas sp. MED121 RepID=A3Y8C6_9GAMM  E=4e-50 s/c=0.92 id=33% cov=83%
---IVYEDAGLMVVNKPSGLAVHGGSGLNFGLVEVVRQLRSK-EKSIELVHRLDRDTSGLIMISKKRSVLKQLHAALREKEgVQKTYQALVYGsWPKRKQQVNAPLLKNELKSGERIVKVHTEGKESLTRFKLLRQFE-----------GYSLVECEPVTGRTHQIRVHTLHAGYPIVGDDKYSPSEQNKE-AKGLGFKRLCLHAAKLDIM--LNDQRILVEVPIDDEWRNAMNQ---------------------------
>UniRef50_Q38VN9(78-296:306) Pseudouridine synthase n=1 Tax=Lactobacillus sakei subsp. sakei 23K RepID=Q38VN9_LACSS  E=3e-49 s/c=0.90 id=28% cov=82%
-LKIAYEDDHFLIVDKPAFVASLPAPNHPNNTMANFvkQYLIDEQAESLavHVVTRLDRDTSGLMMFTKHGFAHSLLDRQLQSKELQKTYIAIASGDMREDLPQHAWIDRPIKRSEEfyMRRVVGEGGKRSLTEYWQAAH-----------GDGATLVKLKLLTGRTHQIRVHFASLGHSLIGDNLYGES--------NDLLPRQALHCRQLTFYHPFEERTITVKSPVPADFSAVLAQ---------------------------
>UniRef50_A5ZQM9(88-325:334) Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC 29174 RepID=A5ZQM9_9FIRM  E=3e-49 s/c=0.83 id=31% cov=82%
---ILYEDEDILAVNKPAGVLTHPAGMHYSDSLanqVAAYFQERNLSVCIRPIGRLDKETSGIVLFAKNQVAAQRLQEQRETGVLEKQYLALVDGNLPKDqddiwHTIDFPIKKIGNHPLRMEAVKKSSSAEnekyiahqltdyincfqAVTHYHVL-----------YSTDKWSAIKLKLDTGRTHQIRVHMQAIGHPLLGDSIYNTSTMNR---EQCTIYRAALHAWKVRLRQPFNGRKIELEVPVPEDFKK-------------------------------
>UniRef50_A7HL94(99-314:317) Pseudouridine synthase n=2 Tax=Thermotogaceae RepID=A7HL94_FERNB   E=4e-49 s/c=0.91 id=31% cov=82%
-LDIIYEDELIIAINKPAGVSVHPGKNvNKPSIIEGLIHYGKENGFEPFLVHRLDKETSGVLIVAKDRSVARELSEIISSRNVEKIYNALVFGKV-QKVTINTPI----------------DGQDAVSHIIPIEYFRVKLNGI---SVELSFLEVEIETGRKHQIRKHLSSINCPIVGDKDYGNFRLNREFSKNFGLKRHFLHCKQMKFV--FNGRNYNILAQLPKDLTTVIKYLN-------------------------
>UniRef50_A6NVX8(79-292:299) Pseudouridine synthase n=1 Tax=Bacteroides capillosus ATCC 29799 RepID=A6NVX8_9BACE  E=5e-49 s/c=0.92 id=34% cov=82%
-FPILYQDRDLIAIDKPAGLLTVGHEGERQRTAyrLLADTLRDGsREKKLFVVHRLDRDTSGAVLFARNEEMKRALQEDWDSLVKERIYLAVTVGAPEREEGVVRSWLRETSTRVVYSGGPGSGAKEAVTRYKVLAR-----------SGEYALVRVALDTGRKNQIRVHMADLGCPVAGDKKYGDGSG--------PMDRLALHAVRLTITDPRTGAPLTVTAPVPKSFLRLF-----------------------------
>UniRef50_Q1WS43(77-294:296) Pseudouridine synthase n=3 Tax=Lactobacillus RepID=Q1WS43_LACS1   E=9e-49 s/c=0.89 id=29% cov=82%
-LDIIYEDSNWLVVDKPPLLSSVPGPSNRTDTLVNrvkfHLWQQKSKDLVPHVITRLDRDTSGLVLVAKHRFAQGLINKQVEEHSIDKKYLAVVEGIItEKHGIIDKPLGPRENGIGQM---VTDTGKIAKTEYWVREYL----------GDKATLVECKLHTGRTHQIRAHFSSINHALVGDELYGGRLDW-------GLERQALHAYQLAYVDPFTQEEKLFKSEMPKDLENLIVRL--------------------------
>UniRef50_Q7NBQ4(84-296:312) Pseudouridine synthase n=1 Tax=Mycoplasma gallisepticum RepID=Q7NBQ4_MYCGA  E=1e-48 s/c=0.92 id=31% cov=82%
-LDIVYEDDDLIIVNKPTNMLSHPTTHNEPDTLLNCLMYHNK-KQKVYLAHRLDKDTTGLIVATKNFKALEKIQEQITKRIMKRYYLAIVHYPFNElRAVIDAPIGYLKDHDLKFGVENTKNPKNAITKIYVLDQ-----------NKKYALIKCELLTGRTHQIRVHMDFIKHNIINDPLYGVKGEQRTDYK------QFLHAYQLELTHPTTNVSLFFEVKPDEVFMKKL-----------------------------
>UniRef50_B1YJB1(81-290:293) Pseudouridine synthase n=1 Tax=Exiguobacterium sibiricum 255-15 RepID=B1YJB1_EXIS2  E=2e-48 s/c=0.93 id=31% cov=80%
-LDILFEDDWLLIVNKPPGMASIPSRLHPERSLsnfVLGYYRQHQIPYAIHIVNRLDRDTSGLVVFAKHSLAHHQLSKMQQNGLLDRRYVALIEGTIP-AQTIDLPIGQTDHSFMERMVRED--GQQAITHI-------LTSEPITAFSRELSRLTIKLETGRTHQIRVHLAALGHPLVGDTMY---------KGTPLIARQALHSASATFPHPGTGEVMTFVAPLPDDL---------------------------------
>UniRef50_Q492Q1(94-323:338) Pseudouridine synthase n=2 Tax=Candidatus Blochmannia RepID=Q492Q1_BLOPB  E=5e-48 s/c=0.84 id=32% cov=87%
---IIYEDDYLLALNKPTGVAAHGGSGLKFGVIEGLRALRPK-AQFLELVHRLDRETSGVLLVAKRRTALVYLHEQLRLQNMKKEYLALVHGRWNVNlQIVSVPLFKKNTllNSSRVVYIDSENGKFSTTHFQIKEYFDNV----------ATFLAIKPITGRTHQIRVHTQYASHPIVGDNRYGDYQSNTRF-KRFGFNRLFLHASILRFIHPKTKKKFHIHAPLGQSFHNCL--FFLRNLSIKN-----------------
>UniRef50_Q013B9(163-468:472) Pseudouridine synthase, RluD (ISS) n=1 Tax=Ostreococcus tauri RepID=Q013B9_OSTTA  E=5e-48 s/c=0.63 id=26% cov=90%
-LDVVHEDDEFLVVNKPPNLRFHPNHRFEGNSLLS-RALHHTKGETPYIVHRLDMDTSGVAVFVKKQSLVSDVARQFHEKTARKTYLAISVGVtPPGCGdgfVVDAPIGDHGVVKEARNVDFSGEGKEARTVCEVISRKEtalfdisdetvaatttpkgvsaTSETNDSSPSATAALVLVKPMTGRTHQIRVHLAHAGLPIVSDALYGPHIRWGAQSAdenekltwsasqlaacssenptqmhqmtppdecdsphpsgvwggSLSIGRQALHAYKLELVHPVTGQMLAWQAEMPEDMRRVCDALG-------------------------
>UniRef50_D0BL50(77-294:296) Pseudouridine synthase n=1 Tax=Granulicatella elegans ATCC 700633 RepID=D0BL50_9LACT  E=6e-48 s/c=0.89 id=32% cov=82%
-LDILFEDDYLLIVNKPQGTASIPSQLHPDQSMANrvkgYLQTTRTQDCVTHVVTRLDRDTTGVMMFAKHRVVHAWMDQALRNKTIQKTYHAIvtKQDVLKEHDLIDAPIGRTDDSIINRCVRPD--GKPSLTEYWLEETYQHSQ-----------LVKIRLHTGRTHQIRVHFSWLGCPLLGDDLYGGEKIEP-------LMRQALHCSQLDFVHPMTGEKMCVKALLPKDMAEWIEK---------------------------
>UniRef50_C2L1H2(90-330:335) Pseudouridine synthase n=1 Tax=Oribacterium sinus F0268 RepID=C2L1H2_9FIRM  E=2e-47 s/c=0.79 id=26% cov=83%
-LDIVYEDRDILLLDKPARLPCHPSPGHFEKTLAgaiVFYQMQNSSASSfvCHFIHRLDLDTSGLILLAKNRLAASVLNKDMKEGRIQRSYLAFCQGNPEFSLGEIQGFTRLEEKKKKEfnyafaisapiarveeekmlRTVNFQKGQEALSYFNVLNYF---------PEKNYSLLQLQLATGRTHQIRVHLSYLSCPLLGDSLYGNGEE-SVFSQNIGLSRQALHSYSISFTHPIRKEKMFFQRELPPDL---------------------------------
>UniRef50_A5WCP4(146-357:364) Pseudouridine synthase n=15 Tax=Moraxellaceae RepID=A5WCP4_PSYWF   E=2e-47 s/c=0.90 id=32% cov=80%
---VVYEDEGLIVLNKPSGMAVHGGSGLDFGVIEAMR--DATSKKYLELVHRIDKDTSGLLMIAKKRSTLKVLQEYLREKTIQKHYLCLVKGQPAlNEFEIDAPLLRYTVANGERRVKVDkanPEAKLSQTTCKVLARFKMN-------GEPVSLIEAMPHTGRTHQIRVHLAYLGHPILGDDKY-------NIKDTSGVRRLCLHAWQLDVP-----EYEVIKAPLPEDMQSLL-----------------------------
>UniRef50_C7RGL6(74-297:305) Pseudouridine synthase, RluA family n=3 Tax=Anaerococcus RepID=C7RGL6_ANAPD  E=6e-47 s/c=0.84 id=27% cov=80%
-LKIVYENDDYAIIDKDSNVIVHPAGKIITGTLVNGLLGRYgydglshiGGDDRPGIVHRLDKDTTGLIAITKTNEAYKYFKKMFETRKVDKYYYAIVFGNFdKKKGTIDNFMDRDVHNRRKMAVRNT--GRRAVSHYEVISEVE-----------GFSLVRIKIETGRTHQIRVHMTHINHPILGDPVYGNVKH------KFNLDHQLLHCGKVGFKN-MEGDYVTYEAIPHEDFLK-------------------------------
>UniRef50_Q2SK59(100-308:315) Pseudouridine synthase n=3 Tax=Gammaproteobacteria RepID=Q2SK59_HAHCH  E=1e-46 s/c=0.90 id=34% cov=73%
----LFENDELLIINKPCGVAVHGGSGVSFGVIEILRAARQDI-RFLELAHRLDRDTSGVLVLAKKRRALVQFHDMLKTGRVEKIYHAWVCGkWPKHKSVITAPLKKNVLRSGERMVNVSEDGKPSETRFRVL-----------YSGAGRTLVEAQPITGRTHQIRVHAKFAGHPIIGDDKYCDSETNRVYRD-MGVKRLCLHAYSLR-----------------------------------------------------
>UniRef50_P0AA37(16-219:219) Ribosomal large subunit pseudouridine synthase A n=205 Tax=Proteobacteria RepID=RLUA_ECOLI  E=2e-46 s/c=0.92 id=36% cov=78%
---ILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDY--PQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPsPAEGLVDLPLICDWPNRPKQKVCY-ETGKPAQTEYEVVEY----------AADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFY------ASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKA--PADF---------------------------------
>UniRef50_B0SGK3(83-303:312) Pseudouridylate synthase, 23S RNA-specific n=2 Tax=Leptospira biflexa serovar Patoc RepID=B0SGK3_LEPBA  E=3e-46 s/c=0.85 id=25% cov=82%
-IPVLYDEDEFMVIHKKAGIACHSGPGDDSPSLVNGLLYQFknlsgtGGERRPGIVHRLDKPTEGVLIIAKTDRAHAALSKLFQDRLVEKTYYAWVlQAPVEAEGTINMPIGRHPVERVKMCVRED--GRMAITHYKTEKIVQTQT------GRKFSLMKLGLETGRTHQIRVHMAKVGCPVVGDSLYSRSAKDYTQY------GLLLFAKKLDFPHPFVpDKRIVVELDFPERFK--------------------------------
>UniRef50_Q04XF3(84-305:312) Pseudouridylate synthase, 23S RNA-specific n=4 Tax=Leptospira RepID=Q04XF3_LEPBL  E=3e-46 s/c=0.84 id=27% cov=83%
-LPVVLEREDYLIIHKPPGIASHSGPGDRSPSLVNGLLHHFkelskvGGEARPGIVHRLDKPTEGLMLIAKNDRAHGKLSELFRKREIEKKYYAWIQGHLPAEtGTIDLPIARHPIERLKMTV--SPKGRKSVTHYKVLKYV------NSRSGRKFSFVEVGLETGRTHQIRIHFQSQRCPVVGDLLYSRTGSQFESY------GLQLLSYYLKFKDPFTGEMIEATLALSERFLR-------------------------------
>UniRef50_C0WQF4(79-293:297) Pseudouridine synthase n=3 Tax=Lactobacillus RepID=C0WQF4_LACBU   E=7e-46 s/c=0.87 id=27% cov=82%
-IQIVFEDEHFLVVNKLSGIASVPAHNRANDSLVNrvkgYYQRNHYANQKIHIVTRLDKDTSGLVIFAKHHFAHSVLDKQLKDHQIKKTYLAIVEGTFSTTHFEIYLPIKRADGSLVKRQVGFP-GKMSITEAWTKQRLR-----------QHTLLKLQIHTGRTHQIRVHMTAIGHPLVGDWLY--------NPEDKSFPRQALHCAGLRFFNPFAGHFVDCRAPLPDDMKTYLA----------------------------
>UniRef50_A1AVB5(89-303:303) Pseudouridine synthase n=2 Tax=sulfur-oxidizing symbionts RepID=A1AVB5_RUTMC  E=8e-46 s/c=0.87 id=33% cov=83%
----LYEDKGLLIINKPSGLSVHSGSGVDVG---IIEALRQIYKKPIELVHRLDRATSGVLLIAKKRSVLKNLHEQLSQHTVEKRYTALVKGVWsKKCHTIDAPLYQNS-----RYIMVDAKGKYAISHFQPLKNFSDGGFS-------ASLVEISIETGRTHQIRVHAKYAGHALACDDKYGDKEFDRQVKFK-GLKRLFLHAHQFIFTNPLTNDIQKVNASLPVELEEFLAKL--------------------------
>UniRef50_C6VWD2(24-251:255) Pseudouridine synthase n=2 Tax=Flexibacteraceae RepID=C6VWD2_DYAFD   E=8e-46 s/c=0.82 id=31% cov=84%
---IIFEDEDFLVVNKPPHLATLDERTADRGGSVL--RLAKEYNPELQAAHRLDKETSGALAFAKNPAAYRHLAMQFEHREVTKRYHAVVNGIHDLEGI-SVYLPILPLKNGTAVKIDRADGKEAETIFNTLQVYR-----------GYTLVECIPITGRMHQIRIHLSCLKAPIVNDPQYGGEPiflsnlkrkfnLKKDTEEQPLIQRVALHARSLSFAL-MNGEDIRVEAPYPKDFEVLVKQLN-------------------------
>UniRef50_D0MHX3(7-223:242) Pseudouridine synthase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MHX3_RHOM4  E=9e-46 s/c=0.85 id=31% cov=82%
-LPVLYLDNHLLVINKPSGLRSQGDRSGaptvlSLGKALIKERFNKPGNVYLGLVHRLDAPVSGVMVLARTSKAAARLMQQFRERTVEKVYLALVEGELEGSGTWEDFIA-PARDHMRLVPEDHPFGKRAVLHWQALMTR-----------NGLTLMRLVPETGRKHQIRVQLAFRGYPILGDRRYRARRWLAPGQ-------MALHAWKLALTHPTRRERMQWTAPVPSFWDEAF-----------------------------
>UniRef50_Q0AFD5(116-354:354) Pseudouridine synthase n=3 Tax=Nitrosomonas RepID=Q0AFD5_NITEC   E=1e-45 s/c=0.77 id=33% cov=88%
-FDTLYQDDYLLVINKPAGTAVHGGSGISYGVIEQLRKQRPDW-KFLELVHRLDRETSGVLLLARKRQTLLELHKQIREGTVRKHYLTLVRGKWKNSlQNVRLPLYKYLTAEGERRVAIATGRND---HDKVQQAYTLFALQKNWEA--FSLLDAELKTGRTHQIRVHLAHLGFPIAGDDKYGDFGLNRQLQKDDGsglvLKRMFLHASVFVCTHPVTGELLRLEAPLPDELRVFLRNL--------------------------
>UniRef50_Q0F1Z5(374-578:579) Pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F1Z5_9PROT  E=3e-45 s/c=0.90 id=32% cov=77%
-IEIVYEDDQLLVVNKPAGLMSTPG-REIEESLFSRLAQRYPQIPELTLVHRLDMDTSGLLLVAKDLRTHKRLQKQFIERSVEKCYEAVLVKRLpaqPDQGRIELPLRVDLDDRPRQMVCY-QHGKPATTRWQIIAR-----------ENNRTRIWFYPETGRTHQLRVHASHrdgLNAAIVGDGLYG-----------LPAERLMLHARRLCFTHPVSREPMVFELPAP------------------------------------
>UniRef50_B9XS18(12-209:536) Pseudouridine synthase n=1 Tax=bacterium Ellin514 RepID=B9XS18_9BACT  E=4e-45 s/c=0.92 id=35% cov=75%
---ILFEDEHLLVVNKPAGMNTHAPSPYAGEGIYEWLKHREPRWASLAIVHRLDKETSGVMVFGKTTVANRSLTEQFTNHSIRKKYLLLTDKVVSSQTsTMVSCLVRVGEKYLSRPV--HAGGEKAETHFEVITKAE-----------GGTLVEAEPITGRTHQIRVHAAEQGFPILGDALYGGTK----------ASRVCLHAAELKLKHPGTNAEMTFRA---------------------------------------
>UniRef50_Q01UA0(81-294:304) Pseudouridine synthase n=8 Tax=Bacteria RepID=Q01UA0_SOLUE   E=4e-45 s/c=0.86 id=25% cov=82%
-FEVLFEDPHLLAVNKPSGLPTLPGGGFLENTLLRLVQKHT---PNANPVHRLGRATSGIVLFARTPQAASNLFANWNTPKIRKIYRALAQNIAQHDAYEILtPIGLVPHPRIGSVWAANPSGKPSKSLAKVISRSTS-----------TTTFEVSLNSGRPHQIRIHLASIGHPLVGDPLYGlTGQPLENLPGLPGDGGYFLHAQFLQFQHPITGEQINLEAALPSGF---------------------------------
>UniRef50_Q6MJF7(13-227:230) Pseudouridine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MJF7_BDEBA  E=6e-45 s/c=0.85 id=30% cov=81%
-FEILHEDLDVIVGNKAAGVLTVAAKWDRDNTVHNLLNLyvrkgNPRSNKCVYVVHRLDQATTGVLIFAKTEQVQHFLKDDWKS--TIKTYYAIVHGKMPKKSGTITSYLEEDENYVVHSSKDSDKGKLAITEYEVLKETE-----------KFSLLKINLLTGKKNQIRVHLAGEGHPIVGDPKYGKPTTN--------LKELRLHSASLEFTHPHSKKRITIKAPVPNYFRTLID----------------------------
>UniRef50_B8K915(23-249:254) Pseudouridine synthase n=5 Tax=Vibrio RepID=B8K915_VIBPA   E=7e-45 s/c=0.81 id=34% cov=74%
-VDIVFEDEHILVANKPSGLLSVPGRLEEHYDSLWSRLVA--IYPDIQVVHRLDMDTSGLMLLAKHKEAERSLKKQFQYRLTHKVYYARVWGHPTNDnGEIDLPLICDWPNRPRQIVCFD-DGKPSKTLYQVVKREE-----------RTSIVRLLPITGRSHQLRVHMQALGHPIVGDEFYSEGEAFEFS------DRLELHAAELSFYHPHS-----------------------------------------------
>UniRef50_C7LVL1(16-219:234) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=C7LVL1_DESBD   E=2e-44 s/c=0.89 id=39% cov=77%
-LAVIHEDRDMVVVNKPSGLLSVPGRTPELFDSVLSRVREIHRGAQA--VHRLDLGTSGVLVVATRRKAETILRQQFQDRLTRKLYLARVQGVMSEDsGQVDLPLICDWPNRPMQMVCHD-TGKPALTDYQVLES-----------DGESTLVLLRPHTGRSHQLRVHMASLGHPILGDNLYGEQRPGE---------RLLLHASQLGLYHPYSGEWTTFHAP--------------------------------------
>UniRef50_Q28K21(14-216:217) Pseudouridine synthase n=11 Tax=Proteobacteria RepID=Q28K21_JANSC   E=4e-44 s/c=0.89 id=33% cov=78%
-LDIIHEDHDLLLVNKPAGLLSVPGKGEHLSDCLIARLKIAF--PEVLLVHRLDMDTSGVMVFARTPHAQRHLGLQFEKRHTKKAYVARVWGEVtDKDGHIDLPLIVDWPNRPLQH-VNHETGKPAQTDWRRIRVED-----------GTTRMRLFPKTGRSHQLRVHMLAIGHPILGDPFY-------ATGPALAFPRLMLHAESLKLRHPDGGIGMTFRARVP------------------------------------
>UniRef50_A8UMR7(358-560:561) Pseudouridine synthase n=1 Tax=Flavobacteriales bacterium ALC-1 RepID=A8UMR7_9FLAO  E=5e-44 s/c=0.89 id=34% cov=77%
-LEIIYEDDFLVVLNKPHEFLSVPGKTIKDSVLTRMQNY-LPDATGPLLLHRLDMSTSGLLLVAKNERTHKNLQKQFIKRIVKKRYVALLNGKLePSEGTIDLPLRVDLNNRPRQLVC-DEHGKLAKTKYEVIE-----------IKNNKTRIHFYPITGRTHQLRVHAAHykgLNMPIIGDDLYGTAS-----------NRLHLHAEMLSFEHPVKREWVSFSCKAP------------------------------------
>UniRef50_Q6MND5(10-227:228) Pseudouridine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MND5_BDEBA  E=2e-43 s/c=0.82 id=31% cov=83%
-IPIVEKSKHWLVINKPSGVSVHNDP--PDVRTLLKKQLTPGTYQDIHPVHRLDKETSGLLLVGLDAETAANLSGQFQEHKVEKTYYALLRGELPvstDWQEWNTPIS-DKAEGRKNPQGLLKDRVEARTLYKVLEANKY-----------FSLVEVRLITGRQHQIRKHTALIRHAIVGDTRYGDPKYNERMANIYQTKRMFLHAARMTVM--INGYKHSFEAPLPPEFKEAMK----------------------------
>UniRef50_Q2LVB7(107-316:324) Pseudouridine synthase n=1 Tax=Syntrophus aciditrophicus SB RepID=Q2LVB7_SYNAS  E=2e-43 s/c=0.85 id=32% cov=80%
-FPVLFEDQHVIAVEKPVGIATFSADGSASVQWIVAQALKEHsrGKIHAFAVHRLDKEVSGVLLFAKSKMAMDHIKE--KWKEAEKRYYALVEGKPESPDGTIESWLVEDHAQKVHSTRESSKAKFSVTHYRIIKQV-----------NQYTLLDVKLQTGRKNQIRVHLSDIGCPIAGDRKYG--------AAADFVRRIRLHAYYLSFPHPVTGERISIESPMPEGFL--------------------------------
>UniRef50_A5EXY5(94-310:313) Pseudouridine synthase n=2 Tax=Cardiobacteriaceae RepID=A5EXY5_DICNV  E=5e-43 s/c=0.82 id=29% cov=83%
---VLYEDDHFLILNKPAGIVVHGGSGHEFGVIDVVRSIW--GENYAELAHRLDGDTSGVLVLGKHRQALNAFQTAMNEGTVEKRYWALVDGVWTReEAEVVVHLTKAPLNVREKMQVSElENAQFARTWFYVLQRWQ-----------DATLMEAVLDTGRTHQIRVSAAHCQHAIAGDKKYGKREFNDLVRKK-GFHGLFLHAREIKFC--YQNQTIHVMAPLTEAMQQLLEHW--------------------------
>UniRef50_A9KNX9(105-338:346) Pseudouridine synthase n=21 Tax=Bacteria RepID=A9KNX9_CLOPH   E=6e-43 s/c=0.75 id=29% cov=76%
-LDVLYEDSHVVIINKPIGMLSQRAKESDVSLVELLIAYLLEMGSltkeelstfKPSVCNRLDRNTSGIVIAGKSLLGLQEMSAKLQDRSLHKYYRCIVKGTMTKGARINGYLAKDEKTNKVRITTNDPNDGESsyiETEYQPI-----------LSKNGYTLLEVLLITGKTHQIRAHLSSIGHPIIGDTKYGDETLNKKMQKQYGLSHQLLHSYRLEFP---------------------------------------------------
>UniRef50_UPI00016C4D9D(126-346:354) pseudouridine synthase, RluA family protein n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C4D9D  E=1e-42 s/c=0.79 id=28% cov=81%
--------------NKPAGLTTMrhkeeaeefGAHGQRFLTKTLAGLLPTLLGtpdRAVTAVHRLDRDTSGLVVFARTRAAGENLTAQFRKHSTERRYLALTRGVPKPGRIASVFVSDRGDGRRGTTTDLAADGKRAVTHVAVLE-----------PLGPFALVECRLETGRTHQVRIHLGEAGAPLCGEGVYDRPIDGQPLPDGSGAQRPMLHATRLGFAHPDTGAAVSWEVPPPEDFRRLLAKL--------------------------
>UniRef50_Q31NG5(338-542:543) Pseudouridine synthase n=2 Tax=Synechococcus elongatus RepID=Q31NG5_SYNE7  E=1e-42 s/c=0.85 id=35% cov=72%
-LPILYEDADLLAIIKPAGLLSVPGTRGLQQASAIQLLRQQFPDLPTYcVVHRLDQATSGILLVARNRPTQVALFEQFRRRQVHKVYEALLEGQPDCTaGTIDLPLRPDWTRRPYQLVDRDR-GRPALTYYRCIDQ-----------TGDRCRMELEPITGRTHQLRVHMAHpegLGQPILGDDLYGQSS-----------DRLYLHARSIRFRHP-------------------------------------------------
>UniRef50_D1XZI5(362-571:577) Pseudouridine synthase n=1 Tax=Prevotella bivia JCVIHMP010 RepID=D1XZI5_9BACT  E=6e-42 s/c=0.82 id=30% cov=78%
-IPILFEDNYLAVIDKPAGLLSVPGKK-LATSVYALLKQKWQGRCKPYMVHRLDMDTSGLMVVAKQAHVYHDLQQQFINRTVNKRYTAflplsLLDKNLPPKGKIILPLTADLFDRP-RQKVDKEVGKIAITTYEIVGKTHYGERLKQLAVR----VLLYPHTGRTHQLRVHCAHsegLGTPIIGDNLYGNK-----------ANRLHLYADRLRFVHPITHKEMTF-----------------------------------------
>UniRef50_A6G5N3(95-309:322) Pseudouridine synthase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G5N3_9DELT  E=8e-42 s/c=0.80 id=30% cov=78%
---------------KPAGLLSVP-WDDRDDRDTLIERtritlreregTRSGERDRLGVVQRLDKDTSGLLVFARTRRARKALEAQFRAHTIFRRYVALVHGAAKAGVHESYLIADRGDGLRgsWRGKSPPKAAKKAITKVRVEEKLD-----------GATLISCQLETGRQHQIRIHLAEAGHPLVGEPVYGRGYRGR----RLPAPRPMLHAASLGFRHPVGDRPVRFEAPPPDDFCAALEQL--------------------------
>UniRef50_Q03TY5(86-294:295) Pseudouridylate synthase, 23S RNA-specific n=1 Tax=Lactobacillus brevis ATCC 367 RepID=Q03TY5_LACBA  E=1e-41 s/c=0.82 id=31% cov=78%
---VLYESADLLVINKTRGSKTHPNqPGERGTTLNHVAAYLGPDQPGPYILSRLDQETTGALLMTKTPAVVPIMVRHIADKQVQRTYLAWVHGRLTGDGVFTDPIGRDPLDKRKRQVNGD-HAQPAVTHYHVCEYRE-----------QATLIQLRLETGRTHQLRVHLAAAGHPLIGDPLYGTATDT---------NRLRLHCWQLTFPQPFTvnDAHTTVTAPVPADF---------------------------------
>UniRef50_Q5WF07(86-295:301) Pseudouridine synthase n=1 Tax=Bacillus clausii KSM-K16 RepID=Q5WF07_BACSK  E=2e-41 s/c=0.81 id=32% cov=78%
-----YEDEHLLVADKPGHMATIPSRDRPGGSLangVLHYYKQQHLQATFHAVNRLDRGTSGLLIVAKHRYAHDLLSRLQQQGGVKRCYKALVTGVLSEKaGIINAPIDRKPGSIIEREV--GPGGKSAITHYKVEAESKT-----------HSLVSLQLETGRTHQIRVHFAYIGHPLVGDGLYGDHGE--------ALAHQALHCDRVALTHPFTDEVLYVEKSLPKEWR--------------------------------
>UniRef50_A0Y082(22-234:235) Pseudouridine synthase n=2 Tax=Alteromonadales RepID=A0Y082_9GAMM   E=2e-41 s/c=0.80 id=31% cov=80%
-FSILYQDNDILVINKPSGLLSLSGKNSENWDSVHYRLVNGQKGLTPAflkakLVHRLDLGTSGIMLVSLNDVSSKHLNKQFQLRSVKKHYVAVLQGCISEDRGQIDAPIAKDTQLFPRVKICKLEGKPAVTEFNVIKRLANPVR---------TYVHFSPLTGRTHQLRIHSHFIGHPILGCDLY------KSAHSEKLSKRLQLHASDLFFEHPTTNQAIHIHCPSP------------------------------------
>UniRef50_A8VZ12(91-301:305) Pseudouridine synthase n=1 Tax=Bacillus selenitireducens MLS10 RepID=A8VZ12_9BACI  E=4e-41 s/c=0.81 id=30% cov=80%
-LSIRYEDEWCIVIDKPAGLLTIPNETYENDSVagrVIGYFKSCDHPATFHPVTRLDRQTSGLMLIAKDRHSHSLFMKQQCAGLIDKEYVAVtPPGFPWIAATVDAPIARHPDSIIERMVHHE--GQKAKT--RLVKVNENASG---------SLIRCKLETGRTHQIRVHLAFTGWSILGDGLY------REEKSADEHKRTLLHACSLRWDEPFTGERIEIHESVPEDF---------------------------------
>UniRef50_B0PEI9(101-304:338) Pseudouridine synthase n=5 Tax=Bacteria RepID=B0PEI9_9FIRM   E=5e-41 s/c=0.83 id=31% cov=74%
-IDIIYEDENILLVNKPAGLVVHEDEHQSSDTLINRIQHHlyncgvynpaEENSFAPALCNRIDRNTAGIVIAAKNAAALRILNEKIKARELQKLYLCIVHGtMPKESDTLKAFLRKDARTNTVAVYDHPiPDGRTILTHYRVVAQKD-----------RLSLLEIDLLTGRTHQIRAHLAHIGHPLLGDAKYGRNRDN----HKTGLKHQALCAYKLTF----------------------------------------------------
>UniRef50_C3RID1(74-269:278) Pseudouridine synthase n=3 Tax=Bacteria RepID=C3RID1_9MOLU   E=1e-40 s/c=0.86 id=30% cov=75%
-LKISYEDENFLVIDKPAGLPSIPTKRYPRNTLanaVVYYYQSQGIKATVHLVNRLDKDTQGLLLIAKNSYAHYLLSRDIK--QVRRVYHCVVEGVLTGQGTITAPIIKDKKSVKRLI---HPAGKFAVTHYRGLEV-----------SANQSKIECILETGRTHQIRVHLSSINHPLVGDTLY-----DSIYQESYYLDSIAL-----SFIDPFTQRLIEVK----------------------------------------
>UniRef50_B3DY53(11-258:268) Pseudouridine synthase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DY53_METI4  E=2e-40 s/c=0.68 id=26% cov=88%
---IVEECQDYLIVDKPPFLLSHPTRKKKGPSILEWLQ-NLHPGISFKLIHRLDRETSGLLVVAKNSAAAAYFGRQMEKRLIQKGYLAISWGELKADYLKIEaplgYLGGAKGNEIVIRQGIVPHGTQSVTEIYPLGH-----------GGGYSLLWVRPLTGKLHQIRVHLSTIRHPVVGDKLYGPNPsfflefakrgWTEEMEKVLLLPRHALHAAYLSFF--WKGDKKQFYSPLPEDLKKFlglvqnLSKLQLNNPILAND----------------
>UniRef50_B2J8D4(368-571:575) Pseudouridine synthase n=7 Tax=Cyanobacteria RepID=B2J8D4_NOSP7   E=3e-40 s/c=0.82 id=36% cov=77%
-LPIIYEDEWLIAVNKPPGLLSVPGRyRDRQDSVLSRLRHLLPDGMALASVHRLDQETSGILLLARDRQTHKQLSQQFQQRQVHKVYEAILSGVaIAEKGVIDLPLWGDPENRP-YQKVDWQNGKPSLTQFQVISR-----------EQDYTRIEFTPLTGRTHQLRVHAAdvrGLGITILGDRLYGCDAVT---------SRLYLHARELDFEHPQLKKTLYLKA---------------------------------------
>UniRef50_UPI000196C65D(76-269:282) hypothetical protein CATMIT_03019 n=1 Tax=Catenibacterium mitsuokai DSM 15897 RepID=UPI000196C65D  E=3e-40 s/c=0.86 id=27% cov=74%
-LKVVYEDDYLMIIDKQPNLACIPVKKYLTESLGNAIMYYykvNHIESAIHLVNRLDKETSGLMMIAKSRYVHDAFSHDIK--QVKRVYHALVKGNP-GQGTVNAPIDHAEGHGTKREVR--EGGKEAITHYRTIKT-----------TGEYSLVECKLETGRTHQIRVHMAYLGCPLVGDPLYGEGEGF------------YLDSVEIAFRHPITQQCMTLK----------------------------------------
>UniRef50_A5WHV7(32-236:237) Pseudouridine synthase n=3 Tax=Psychrobacter RepID=A5WHV7_PSYWF   E=3e-40 s/c=0.81 id=32% cov=78%
----VYEDEDLLLVDKPAGLLSIDGK----DLKVSLLSRLERANPEVKLIHRLDMDTSGLMIFAKNKQAQTHISKQFIERIPQKEYQAIVQGTLAIPGKKgeINIPVRYEPSIKPKHVADPEWKKHALTHYEVLHH-------ELRKGRPVTRVALHPVTGRSHQLRVHMVHLGHVIIGDPIY------AEGEALSLAPRLNLHAHKLRLKHPTMNTWMAWESAVP------------------------------------
>UniRef50_C6VIZ5(87-293:300) Pseudouridine synthase n=3 Tax=Lactobacillus plantarum RepID=C6VIZ5_LACPJ  E=6e-40 s/c=0.80 id=34% cov=78%
----LYQNSDLLVVDKPAGVKSHPNQPGETGSILNDLAATLQPTQQvPYMVHRLDQMTSGAMLVALNPVVVPILDRLISDKQIRRTYYAWVRGHFATPTGHFTAPIGHDATDKRKRWVNTADAQPALTDYEVCAT-----------TAHQSLVKLTLHTGRTHQLRVHLAASDHPIIGDPLY--------DSQAESAPRLMLHAQLLDLQLPFSTTRVTVPAPLP------------------------------------
>UniRef50_A8BWX6(1-224:250) Ribosomal large subunit pseudouridine synthase D n=2 Tax=Giardia intestinalis RepID=A8BWX6_GIALA  E=8e-40 s/c=0.74 id=28% cov=82%
MVSVVFENDDYTVINKPPNL--HIDGDYPQ---TVRSWYLATRGRAPRFVNQLDYPTSGLMVIASSRKAAGFAGREFQARAVAKTYVALVVGDVA-SQTISAPIADDAADPRQFCMCISETGKHSETHVERIAAIpeDLRELSPSLPQGLYTLVVLRPVTGRRHQLRLHLAHIGHPIVGDQLYGGGLTDTNQCGEE--ERLCLHALMLSIPN-LSGLPL-LEAPL-------------------------------------
>UniRef50_A8SLC1(85-316:318) Pseudouridine synthase n=1 Tax=Parvimonas micra ATCC 33270 RepID=A8SLC1_9FIRM  E=1e-39 s/c=0.71 id=28% cov=74%
-LDIIYEDENIIVMNKPKNLLSHASSKEDYGNNLVdfmigYLLEKGDYNPRaektfvPAIINRLDRNTSGLVIGAKNSKALRELNR-LKENSIEKYYKTIVSGKVKKNFVINEKLEKDEEKNKSTI---SKNGKDSITEIYVEKNNDE-----------FSLLKIKLITGRTHQIRSHLSSKGFYIIGDIKYGNAKVNKFFRDNFNLRSQFLHAETIIF----------------------------------------------------
>UniRef50_Q30NR3(77-290:304) Pseudouridine synthase n=1 Tax=Sulfurimonas denitrificans DSM 1251 RepID=Q30NR3_SULDN  E=1e-39 s/c=0.77 id=33% cov=73%
--------ERFVVFDKPSGMLIHP--QNRFTEYSLIDELKAQFGMNANIAHRIDQETSGLVLCAKDKKSEVDIKMMFQERDMKKKYLAMVHGELKEELRIDAPLLRYDDEKsalVRMVVKVDPTGKESLTFVRPLKYF---------PITDTTLVECSPHTGRQHQIRVHMFHMKHPIVGDPVYGQSEESvvryldrkierDERVKLSGAKRLLLHANELEF----------------------------------------------------
>UniRef50_B1XIP1(60-275:282) Pseudouridine synthase n=1 Tax=Synechococcus sp. PCC 7002 RepID=B1XIP1_SYNP2  E=5e-39 s/c=0.75 id=28% cov=80%
-FQILHQDPHFWIIDKPAGLPVLPAGNFLENTL-LAQLKRQFPDETPVPIHRLGRGTSGLMILGRSPLGRQSLTRQLREHQITKIYRAvIPAGDYPDQITITTPIGKIFHPSLGTIFAATADGLSAHSEMRVLERL-----------AKVSRVEVQIFTGRPHQIRIHMAAMGFPLVGDRLYlpGGLPAIYEDANHSPLPGDCgysLNAYYLKFQHPHQDKPIDF-----------------------------------------
>UniRef50_A9NFY2(76-276:277) Pseudouridine synthase n=1 Tax=Acholeplasma laidlawii PG-8A RepID=A9NFY2_ACHLI  E=6e-39 s/c=0.81 id=27% cov=77%
-LDIIYEDDDIVIVNKPFNVIVHddGASEDHLTRRVNMHFQYHGYHHQVLPAHRIDKETTGIVVFAKHFIALAYLSNLFESRQVVKNYICVVENKVKDKTGSIE--SKLIKDSKLQKMVVSPHGKLAITHYELLGYEATR-----------SRLKVQIETGRTHQIRAHMASINHPVVGDILYGVSS-----------SRLLLHFSEISFPMIRTKKVEHFVSNPP------------------------------------
>UniRef50_B7AN06(47-280:297) Pseudouridine synthase n=1 Tax=Bacteroides pectinophilus ATCC 43243 RepID=B7AN06_9BACE  E=8e-39 s/c=0.69 id=27% cov=87%
-LKVMYEDEDIVIIDKPSGMLSQkASAGDKSLVEYVTEYLldtgsltqKDLITFRPGICNRLDRNTSGLVVAGKTIKGLQEMSEAFRDRTLHKYYICVVAGRINERSRVSGYLVRDEKTNKSTIY---ADYKEAMDNAEAdMINNIETEYIPAVSNDNFTLLKVKLITGRTHQIRAHLASLGHPIAGDVKYGSRQINKRMSDQYHIKSQMLHAYEL--DYPQRG--LCVRTDIPKEFDRVLK----------------------------
>UniRef50_D2R6S8(7-224:230) Pseudouridine synthase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R6S8_9PLAN  E=1e-38 s/c=0.74 id=32% cov=80%
-LDILHEDNHLLVINKRPLLATQGvAEGTPSLVTEVQQYLkvkyKKPGNVYVGVVSRLDAHTSGVVVLARTSKAASRLAEQFREQGVEKTYWaAVEAAPEPASGELVSWVVKDDKNRRMTIAdRKLAGCQKAVLTYETLEQNKS-----------AALVSVKLETGRKHQIRLQLAdELSLPVIGDRKYGSRIEFPEG--------IALHARELAFDHPVGGKRLSFVAPLPATWK--------------------------------
>UniRef50_Q12RE8(386-593:593) Pseudouridine synthase n=83 Tax=Bacteria RepID=Q12RE8_SHEDO   E=3e-38 s/c=0.77 id=34% cov=77%
-ITVIYQDEHLLVISKPAEFLSVPGKNISDSVHTRI-IRDFPSASGPIIVHRLDMSTSGLMVIALNKEAHESLQKQFILRTVTKRYIALLDGLLPNrtagdEGIISLPLRGDLDDRPRQLVC-HEHGKSAETRWQII-----------DIQQGRTKVFLYPKTGRTHQLRVHCAHsqgLHLPIVGDDHYGVR-----------ASRLHLHAESLSFTHPQSREALHFQ--LDADF---------------------------------
>UniRef50_C4Z9Y6(95-322:324) Pseudouridine synthase n=1 Tax=Eubacterium rectale ATCC 33656 RepID=C4Z9Y6_EUBR3  E=3e-38 s/c=0.71 id=32% cov=83%
---VVYEDDDILAANKPVNMLSQKSKetDISANERLIGYLIKEGkldfdtyKSFKPSVCNRLDRNTSGLILMGKSLHGLQYLSQVLKARTAEKYYMALVAGEVDEPMTIEGFLTKDEAVNKVQITREpiSDESLPIKTAYRPLKTIDMSA-----SCHKATLLEVHLITGRSHQIRAHLSSIGHPIIGDIKYGDRRINAFYKENYHVTSQLLHAHHVILPD---GRY--IEAALPDIW---------------------------------
>UniRef50_Q0CVH8(108-308:507) DRAP deaminase n=1 Tax=Aspergillus terreus NIH2624 RepID=Q0CVH8_ASPTN  E=3e-38 s/c=0.80 id=27% cov=70%
---IIHEDDDLLVIDKPAGVPVHAAGRYHYNSIIEILRNENGVEWMPRPCNRLDRLTSGVMFIGKTAKGAEKMCAKLQQRTVQKEYIARVKGRFPDGvVICDQPIMQVSPKLG--LNRVRATGKDAKTKFRRIayyppaapaageedsqgegeERAATPPPALANEDEGYSIVHCLPLTGRTHQIRVHLQFLGHPITNDPIYSNRR---------------------------------------------------------------------------
>UniRef50_Q6AIJ2(4-206:211) Probable ribosomal large subunit pseudouridine synthase A n=1 Tax=Desulfotalea psychrophila RepID=Q6AIJ2_DESPS  E=4e-38 s/c=0.79 id=36% cov=76%
-LKIIYRDDHLVVVIKPGGLLSVPGRG-PENSDCVSSRLQAKIPEMITqpAVHRLDMYTSGLMVYAVSKEIHRALSIQFQEQQVDKKYTALLEGCLqEVSGEIRLPFRVDLDNRPIQI-LDYQHGKMGITLWRKM-----------DEKNGITRVEFTPMTGRTHQLRVHAAHakgLGIPIIGDSFYGSGRDGDE---------MMLHAHQLSFTHPIIGEKLYFK----------------------------------------
>UniRef50_A4E9L1(1-202:205) Pseudouridine synthase n=1 Tax=Collinsella aerofaciens ATCC 25986 RepID=A4E9L1_9ACTN  E=5e-38 s/c=0.79 id=30% cov=76%
-----------MAIDKPAGMIVHGDGtGERTLTDYASDLLLAMGDgfaaTDMQPLNRLDRNTTGVVLFSLDKQTQPAFDQMVNDHAFEKHYLALAEGKIDWnEKLIDKPIARDRHDSRKM--RVGASGKPSQTRVKVLKRLKSRRGLPTR-----SYIDVELLTGRKHQIRVHLASEHHPLVGDDLYGTARPC----------GLMLHAHSVSFTHPVTGEHIHIEAPCP------------------------------------
>UniRef50_A6DTB9(82-286:290) Pseudouridine synthase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DTB9_9BACT  E=7e-38 s/c=0.78 id=24% cov=79%
---ILYEDENLLLVDKPHFLPIHPAGPYVKETLV-YRLRESQNNPDISPLHRIDRLTAGLVFFSKKVSIRKDYQLLFENRLVEKTYHAISAGPAPDQGYWHLK-NRIEAGEPWFLSAIKEGKANSESYINVIEAKDNLVKF-----------ELKPISGKKHQLRVHLASIGYPILHDPLYPSFVEKPPDNYE---KPMQLLAQSIAFTDPFSKKRHSFQSQL-------------------------------------
>UniRef50_D1QMM7(322-518:522) Pseudouridine synthase n=1 Tax=Prevotella oris F0302 RepID=D1QMM7_9BACT  E=1e-37 s/c=0.81 id=35% cov=74%
-LEWIYEDKDIVVVCKPAGMLSVPGKSLRENVRSLVRQRHPE-ATGPMIVHRLDMATSGLLVVALNLKSYIDLQRQFEEHSVQKRYVALLSrpHHGARSGQISLPLRPDLYDRP-RQIVDAVHGRKAVTNYQ---------------QTGENRMNLYPLTGRTHQLRMHCAHadgLNNPIKGDELYGTRDE-----------RLYLHAEELSFVHPGTGKRMHFEC---------------------------------------
>UniRef50_A9HEJ0(12-224:227) Pseudouridine synthase n=10 Tax=Acetobacteraceae RepID=A9HEJ0_GLUDA   E=1e-37 s/c=0.74 id=28% cov=82%
-FPVLFRDNRFIVIDKPPGLPVHPGPSGGPSVEDSFPLL-SRRADGPWLAHRLDRDTSGCLLIALRKQALLAAQAAFAAGQVRKTYWAVVQGRPAADSGTVAMTMARHSDRQGWRMVAAPDGQASRTDWRVLAS-----------DGRESWLELHLLTGRTHQARLHCASLGCPILGDPVYGGAEG----------PTLHLMSRHLAL--PLS-PPVSATAPPPAHIRATLDRHGWQGI---------------------
>UniRef50_Q041R0(86-281:285) Pseudouridylate synthase, 23S RNA-specific n=28 Tax=Lactobacillus RepID=Q041R0_LACGA  E=5e-37 s/c=0.80 id=32% cov=72%
---VVYEDSDILVIDKPTGQKTHP---NLDEKDTALNDCATYLGYSPFIVHRLDMLTNGLLLVAKNPAVVPILNRQLTNKTLHREYLAWvsKSNQLKQSGTISLSIGHDPDDQRKRMVRLD--GQKAITHYEVIKECENKE-----------LVKLTLETGRTHQIRVHLAALGAPIIGDPLYNPNYQNGEK--------LQLTAYQLTFMGPF------------------------------------------------
>UniRef50_Q11NL4(10-219:223) Pseudouridine synthase n=2 Tax=Bacteria RepID=Q11NL4_CYTH3   E=8e-37 s/c=0.74 id=26% cov=78%
--HILYEDNYILVVNKPCSLMVEPDRNGHPNLLqqvqkYVKKSLHPNKEVYVQHIHRLDRPVSGIVLFAKKKSMLKELSEQFAQRTVKKYYQALTRKVTTNgKGALNHWHFKDSKNKKAILYKEEQQETSAVS----------LGYSTSDYNADYTLWDIQLNTGKYHQIRAQLSFEGYPILGDECYKSTDVYAPNA-------IALHACKLEFVHPVSKESMRLEA---------------------------------------
>UniRef50_Q7UWB9(19-231:232) Pseudouridine synthase n=1 Tax=Rhodopirellula baltica RepID=Q7UWB9_RHOBA  E=1e-36 s/c=0.73 id=31% cov=79%
MIEILWQCHACVVVNKPVGLPTTSPKGTDSLESCLREQFAQAGNPvsYLTAVHRLDRPVSGLVLIALRKKAARLLSEQFRLRHVQKKYIAMVQGNaleaCKQEPWHDTIAKLTDEARVEIVGLDSTDGRQAETKVSFLEY---------DSESDTSRIELRPVTGRMHQLRIQSAHRGHPIVGDPLYGTAEDESA---------LRLVAAKLSFRDPTNGRAVEVELP--------------------------------------
>UniRef50_B7PYG1(184-441:443) Ribosomal pseudouridine synthase, putative n=1 Tax=Ixodes scapularis RepID=B7PYG1_IXOSC  E=2e-36 s/c=0.60 id=36% cov=85%
---VLYNDNDILVLNKPYGMLCHGPAPGVSDACVLTKLLPDlssalypRQDAKLYTVHRLDRDVTGVLLLARTQRMADMLNSLFQKHQVSKTYLAITAGVPDHlEGVIDMPLAEGEVEGAKRMVLNPKLDPEfqrlvpkfrksfaAVTTYRVLAS-----------CGRAGYLELRPTTGVKHQLRAHLGlGLRCPILGDHKYSHLRRLAPQKlPGDMLDRlgirqskvrdapLHLHARAVVVPEILDGRNLTVAAEVPYHFAKNLRRL--------------------------
>UniRef50_A0C2P1(97-275:469) Chromosome undetermined scaffold_145, whole genome shotgun sequence n=1 Tax=Paramecium tetraurelia RepID=A0C2P1_PARTE  E=2e-36 s/c=0.86 id=28% cov=67%
-VDIVFEDDSFVVVSKPPSMIVHTGGGYHYNCLSAILHFEHGL-KDLYVLHRLDRLTSGLLIFSKNRLLAQKFHDANSKLNVQKTYLARVQGNFSEDiKENNKPQYCVSMKDAIFACCTEEdaqklDAKSATTKFEKLWY---------DPISDSSLLECKPITGRTHQIRVHLADLGHPILNDIGYGGK----------------------------------------------------------------------------
>UniRef50_Q4RM58(178-360:516) Chromosome 10 SCAF15019, whole genome shotgun sequence. (Fragment) n=5 Tax=Euteleostomi RepID=Q4RM58_TETNG  E=1e-35 s/c=0.83 id=32% cov=65%
-LEVLVDDGEVLVVDKPASIPVHPCGRFRHNT-VIFILGKELGISELHTVHRLDRLTSGVLLFARTLETSKKLDQLVRDRKLEKEYVCRVEGEFPeEEVICEQPILVVSFKVG--LCRVDPKGKECRTVFQRLS-----------FNGKTSVVRCLPVTGRTHQIRVHLQYLGFPILNDPIYG------------------------------------------------------------------------------
>UniRef50_Q6DBR0(92-358:358) RNA pseudouridylate synthase domain-containing protein 4 n=5 Tax=Euteleostomi RepID=RUSD4_DANRE  E=1e-35 s/c=0.57 id=30% cov=85%
----LYEDQNIIAINKPYDVPLHNINGIRNSIAECLPLLAKitdnmRPGSQLHLCHKLEKETTGVLILAKTEEAAEHVQTLIQSHKVEMKYLAITVGVPvPSEGVIDIPVIERavvgpqphfkmalsplfkvnEDGDGVTRVRAHRQAHAAVTRYQVL-----------DNTSGCSLVELQPLTGVKNQLRVHMAlALTCPILGDHKYSHWSKLAPQKLPEGTLRrlglvqsktrylpLHLHSRRIVLPGFKGHRDITVSCPLPKYFINALKRL--------------------------
>UniRef50_B0D7R4(31-267:321) Predicted protein n=1 Tax=Laccaria bicolor S238N-H82 RepID=B0D7R4_LACBS  E=2e-35 s/c=0.64 id=29% cov=85%
----LYVDPAVAVVTKPHGLVCQlihrqlPAGRVNHFNVMMQDLkAHLSLETFPYPVHRLDKSTTGAFLLALTESSARQLSQQFQKRTVQKTYLALVRGGEKSFPEKFGEIRTTLNKVDGYPEVDlSSQGQPCATDWKLLAS---------SPIAPISLLELNLLTGYKHQLRVHLAKCLHaPILGDAQYSKKPLSSAITDVVKIPedRIFLHASEISFLKykssgPHKQFRLAVRAPLPREFLKLCKDL--------------------------
>UniRef50_Q0I6U3(91-317:327) Pseudouridine synthase n=11 Tax=Synechococcus RepID=Q0I6U3_SYNS3   E=4e-35 s/c=0.66 id=24% cov=85%
-LEVIHDDGDVLVVNKPSGLPVMPGGGFLVHTLTSLLERSSRSVGEvlvPKPIHRLGRFTSGLQVCARRPETRAALSKQFRpEGDCRKTYLGLTHRLESLQQGQTLVIQTDVVERQHPLLGWVWGPEPSTPEPLRRRLSAHSEVQLRERGEREDLLEVQIHTGRPHQIRIHLAQLGFPLLGDPLY-QSDQGLCATATPGDGGYHLHAWRLEgLCWP-TSKWLSLKAQPP------------------------------------
>UniRef50_A0JSJ6(88-307:314) Pseudouridine synthase n=2 Tax=Micrococcaceae RepID=A0JSJ6_ARTS2   E=6e-35 s/c=0.68 id=25% cov=83%
-LSILHQDDHILVVDKPHFLPTTPGGTYIQESALV-RLRNQLDLPDLIPMHRLDRMTAGILLLSTNPETRGKYQVLFEKRQVQKEYECVSAAEPaagyPAVGFPVVVRNRMTKSRSYLLAEVVDGEPNAETRIELTKTFDAGTHASEPARRG--LYRLEPHSGKTHQLRVHMASLGLGIVNDAFYPELLDKAPDDYTRPLQ---LLARGIRFIDPITGQPVEYRSRL-------------------------------------
>UniRef50_A9V182(13-287:289) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9V182_MONBE   E=6e-35 s/c=0.55 id=28% cov=90%
---VIYEDNHLVALNKWRGLAVQDAAGSPSTVLSNVDvFQQNKDGFVPRLAHRLDQNTTGVLVLAKTAEAVLRLNRLFQLGAVAKTYEAVlagqvtkptgtLKGIPELITEEEDANSELTSNQPLFKTSASWSHSTAQSHYTVLASAQVNDGRPSRTKPWLTRVELRPTTGYKHQLRIQCAdGLRAPVLGDKRYGGGQEQVSPIILQHLQRhglrtaahpyglvMHLHAKQLVIPgYNWDGSDLVLRATLPDHMQLTIDACG-------------------------
>UniRef50_D1J3S4(187-475:476) Whole genome shotgun sequence of line PN40024, scaffold_180.assembly12x (Fragment) n=3 Tax=Magnoliophyta RepID=D1J3S4_VITVI  E=7e-35 s/c=0.52 id=34% cov=65%
----LYKDPAIIVVNKPPGLPVQGGIGIKRSLDELAAtYLRYDCSEPPRLVHRLDRDSSGILIMGRTQTSATILHSIFrektfgasnndidtKKRILQRRYWALVIGSPrRPRGLISAPLGKVVVDDGKseRITIVDnvqtMSSQHAITEYRVIKS----------SCHGYTWLELSPLTGRKHQLRVHCAEvLGTPIVGDYKYG------------------------------------------------------------------------------
>UniRef50_B3Q780(22-319:322) Pseudouridine synthase n=8 Tax=Bradyrhizobiaceae RepID=B3Q780_RHOPT   E=1e-34 s/c=0.50 id=31% cov=87%
---VLYRDGLMLVIDKPPGLPVHRGPKGGPNLEASFDALRYGLPRPPVLAHRLDRDTSGCLVLGRHRKATATLGLLFKHSRISKTYWAIVEGGPTEDQGSIDLPIAKLNAERGWWQKVDPEGLPSLTKWRVMGRsgvlpaaatttsatsapirdattsgspppcgegsgvgvhsgsltsgrphpnplpragegvrpargeadnlsRKPGAILGAPPPTQLTWLALEPITGRTHQLRVHCAAMGWPILGDNIYGNGP-------RFGEPRLHLHAREIVIPLSRNKPPVVVTAPPPTHMHPRLSACGW------------------------
>UniRef50_C4G2Q7(5-224:236) Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4G2Q7_ABIDE  E=3e-34 s/c=0.67 id=29% cov=77%
-IPILYEDEDIIVCVKPVGILSQ---GDKDGNKDLVRELKKHLvisarknkqsigkEPYIAVVHRLDRNVRGIMVYAKTGRAAAGLSKQIAENKLTKRYMAVVSFTPERctpeinvEKKRIDYIAADKVKNISTIAeKESKGAERAELNYKVIKT-----------AGNKALVQVDLITGRHHQIRLQLSQIFNGIVGDTKYNDDYKLTDGWKDP-----ALEAVELSFVHPVSGEKLSF-----------------------------------------
>UniRef50_A1SV26(85-290:303) Pseudouridine synthase n=3 Tax=Gammaproteobacteria RepID=A1SV26_PSYIN  E=5e-34 s/c=0.71 id=25% cov=78%
---ILFQDEHILVAHKPHFLAVTPGGKYVNECLQN-RLRRSTGIEALQTLHRLDRVTAGLVMFSVNPDTRHRYHQLFKTRQIHKSYQAIasISDAENLTGQEWEIKNRIVQGEPRFRMRVTEGEANSHSVIRCLRQ-----------SAQTALFELTPVTGKTHQLRVHMQALGLPILNDKYY--PQLEPLSADNYAAPLQLL-AKELQFIDPVTEKPRCFRS---------------------------------------
>UniRef50_Q1JXL0(84-287:294) Pseudouridine synthase n=1 Tax=Desulfuromonas acetoxidans DSM 684 RepID=Q1JXL0_DESAC  E=6e-34 s/c=0.72 id=26% cov=79%
---ILYQDDALLVACKPHFLPVHPGGRYVTENLV-YRLRLATGNDQLAPVHRIDRFTAGLVLFAQRSEDRARYNALFSQGNIKKRYDAVAHCPEEPQQRHWQVANRIEQGDPWFRWQVVAGDVNARSSIELL-----------DLRQGYGLFSLQPITGKTHQLRLHMSGLGFGLVNDRYYPNLLPEQPDDFSTPLQ---LLAKEVIFTDPVTGKHHHFESP--------------------------------------
>UniRef50_Q5Z213(14-231:260) Pseudouridine synthase n=2 Tax=Actinomycetales RepID=Q5Z213_NOCFA   E=8e-34 s/c=0.67 id=30% cov=81%
----LAEDDAVLALNKPAGISV---TGERHDTDIV--ELAAGAGERLFPVHRIDKVTSGLVLLAKDLAAHGTLTRQFTKRTAEKAYLAVVAgGGLPDRGVIELPLSVGRKNRVRiaapRESIRAEDGRWFVDDADLLAVKNYPSRTEFvtlARTADRTVLALRPVTGRRHQIRVHLAWIGHAIVGDPL---------FDKSAAHPRAHLHSWRLVLDAPwRTPPELDLTAPPDAGF---------------------------------
>UniRef50_Q1N0K9(3-182:223) Pseudouridine synthase n=1 Tax=Bermanella marisrubri RepID=Q1N0K9_9GAMM  E=1e-33 s/c=0.81 id=35% cov=70%
-IDIVYEHQDWILVNKPEGVDFHS----QNGEVGFHRQLCDQLGFNVFPVHRLDKATSGLLLFAKSQDACRGLVELFSQRKVEKYYLAIVSNKLKKKQGKVFGDMVKSRNGSYKLTQERRN--PAFTQF-----------LSQALKPGYRLALLKPKTGKTHQLRVAMKSLGSAIVGDQRYGGESAN----------RLYLHAYALKF----------------------------------------------------
>UniRef50_C1MYF0(66-441:443) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MYF0_9CHLO  E=1e-33 s/c=0.39 id=29% cov=93%
---VLYRDDDVLVLNKPSGLPVVGTGTGNANaaapSLSAMLasltfHADAPWKPPLTIVHRLDKDASGCVVLARRAVAARTLARAFAAKSasggegareeeeegllgggraesdalynIERTYWALVAGRPSRDeGVIRAPLRIPGKRNGNTKRRdggvvffaddatderrarlprppdvapgggggasegrveatteDDPRGVRAVTSYRVIGEVPRDADGDDGDDdekvthPRPTLLELTLSTGRKHQIRVHLAsALGTPVVGDYKYGYRDTPRTRRGREIAPpawmealrdveaaarrgsgtirdpasaaawrarrslaladddgggvPLHLHARSLRFPKPSGGDVVRVVAPLPPHLASALERLGVKVSVENGFR---------------
>UniRef50_C8NY78(108-321:339) Pseudouridine synthase n=1 Tax=Corynebacterium genitalium ATCC 33030 RepID=C8NY78_9CORY  E=2e-33 s/c=0.68 id=26% cov=78%
---VVYEDDAIMVVNKPPFLATMPRASHITESATV-RLRRSTGNEELTPAHRLDRMTSGLLLFTKKASVRGAYQQLFASRAVAKLYEAVADDIGPslparpsanSPLVWEHHIVKREGELASSITVDAiPNSLTYVTDITPLQ-------------GGAARYLLQPVTGRTHQLRVQMHAAGAPIHGDPVY---PELLPASAEDFTNPMLLTAVGLAFTDPLTGVKRTFSAP--------------------------------------
>UniRef50_A3YUH6(87-327:328) Pseudouridine synthase n=1 Tax=Synechococcus sp. WH 5701 RepID=A3YUH6_9SYNE  E=2e-33 s/c=0.60 id=26% cov=82%
---VIHDDGDLYVIDKPSGLPVLPAGGFLEHTLLRLLERSCAAQALPRPVHRLGRHTSGLLVCARRPQSRAWLSARLRESTaqllnqpgsearsaatragaCRKVYRALTVPaplqlAPGESLAITTPIGRRPHAGLGQIWaadgPDDPGALPAWSEMRLLERRPQGH-----------LVEVSIHTGRPHQIRIHLASAGVPLLGDPLYRPGGEPRPGA-LPGDGGYLLHAHRLRLPLPAGG-WLDLEAPVPPEL---------------------------------
>UniRef50_C3PFH5(73-267:268) Pseudouridine synthase n=5 Tax=Corynebacterium RepID=C3PFH5_CORA7   E=3e-33 s/c=0.74 id=26% cov=75%
---VVFEDGDLIVADKPHFLPTTSNGRIVRETLQTRLRV-DLNEDSIVPLHRLDRLTSGLVLCSRNPRTRAAYQQLFQKRVVVKHYRAQVAAPFSFDGTVRLGMRRV---RGERQVRVDSTGTPTVTRVRASGTTAD----------------VWPLTGHTHQIRVVLNHLGHPIVGDDTYPVDRGLDLYDFSTP---LLLSHVALSFSDPVTGRKREFQ----------------------------------------
>UniRef50_B7CDE9(49-245:253) Pseudouridine synthase n=1 Tax=Eubacterium biforme DSM 3989 RepID=B7CDE9_9FIRM  E=4e-33 s/c=0.73 id=27% cov=68%
-VDILYENTFLIVAFKPPFLLVHDDGNNQDTLqaRVNGYLQLNQNKYPAQAIHRIDYETSGLVLFCKHPFFQAYCDKNMEEHHIKKEYIALVQGHTNYKNKKIISNIARDRHNAKKMII-HPNGKESVSIFNTLKNYK-----------DCSLIQVTILTGRKHQIRVQCASLNHPILNDSLYGGKKIDNTG----------------------------------------------------------------------
>UniRef50_A8JB96(96-303:303) Pseudouridine synthase (Fragment) n=1 Tax=Chlamydomonas reinhardtii RepID=A8JB96_CHLRE  E=7e-33 s/c=0.69 id=29% cov=78%
-VDVVYEDADMVALSKPSGLQVLPAAMFHQRTVLSLLRRRQYLDV-PAPVHRLGRGTSGCGAAALAALIssapASGSGCQLPLR---KFYRALVQGRVKADqGRVDVPIGPIPHPGVDRgLFAATPDGKPAASVWR-----------AGCMEAECTLMEVEILTGRPHQIRIHMAAMGHPLVGDPLYGAGGRPKVRYRLYGSDcGYYLHSLELHLPHPITGQPL-------------------------------------------
>UniRef50_Q6NEJ6(129-344:349) Pseudouridine synthase n=6 Tax=Corynebacterium RepID=Q6NEJ6_CORDI   E=7e-33 s/c=0.66 id=21% cov=82%
---VVYEDDTLLVADKPPFLATMPRGKHITNSATVQ-LRRSTGIDELSPAHRLDRLTSGLLLFTKRKRVRGAYQTLFSERNVRKTYVATAQYNPSItPGTIWRSHMTKTAGEIQGHIIDAP--PNAETLVSAIERIDAPTQQHLHALHGtdvdLAHYTLKPHTGKTHQLRLHMLAAGVPILGDTIYPTILAEDAEDYSRP---MHLTSTELEFIDPLTGRPRLFT----------------------------------------
>UniRef50_B5EI85(84-287:293) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=B5EI85_GEOBB   E=1e-32 s/c=0.70 id=22% cov=79%
--EILFQNDELLVACKPHFLPVTPGGEYLSQSL-LHRLRESTGIHDLVPLHRIDRETAGIVLFSANPKTRGRYGELFREGSIEKSYEAISAAPVEPGQAEWLVENRLVHGEPWFTMRTEQGPPNARSLIRLVEQRD-----------GAARFQLTPVTGKTHQLRVHMSGLGLQILHDRLYPQLQPQQPDDFDRPLQ---LLARRVRFRDPLSGRLLEFES---------------------------------------
>UniRef50_UPI00006CDA44(89-306:881) RNA pseudouridylate synthase family protein n=1 Tax=Tetrahymena thermophila RepID=UPI00006CDA44  E=2e-32 s/c=0.65 id=27% cov=78%
---IIYENKNIIILNKANGVSCQGGQDVSLNLVTMgQQYLINQTNQKYLVAHRLDKVTSGVLMVPKNQQIAKIYGNLFNDKSnINKYYIALVRNSPKNFKAMINAPIEYSQSKQRAIVsnIIDENSKSAHTHYQVLAQFKMEDKNLAakiinsehdyiKDWGDFSLLKIRIQEGRKHQIRVHLSEIsKTPIVGDARYFDKNHQESLFQYNKDQSIFLHCYQ-------------------------------------------------------
>UniRef50_C8X5P4(88-273:299) Pseudouridine synthase n=1 Tax=Desulfohalobium retbaense DSM 5692 RepID=C8X5P4_DESRD  E=3e-32 s/c=0.76 id=26% cov=70%
------ETETLLVLAKPAGLPVQPGSKHGASLVRELAKAYPETPWPPQPVHRLDKDTSGIILVAKRADVFQIIQQAWQRGEVQKDYLAWLApgdDVGPGWHTWRDRIEICHTDRGEKMCCT-EGGKEAILHLRPLRRNSLGEI----------LVAIQLETGRKHQIRVQSANRGLPVVGDRKYGQTSQK---------TGLMLHAWRLG-----------------------------------------------------
>UniRef50_C5L5W9(272-525:604) Ribosomal large subunit pseudouridine synthase D, putative n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5L5W9_9ALVE  E=4e-32 s/c=0.55 id=27% cov=85%
---VLHRDADFIAINKPWGLSVTDGPKVKY---SLQRHLRAFTSPSssevPILIHRLDTATAGVQLLARHKSAATMARDRIGARSFwNRIYWVLVWGRVqlgprQFSGTINIPLIHRGHHVKPASFHTAE--LSAITRWEILK--------FSPFAGGITLLKLEPYTGRRDQLQAHCAFgLRTPIVGDDVYSKEaiRWNDAYPEKHMLQRKemfgeelickrMVCSRQIS-MHSFGGDQIDIIAPVPPHMQQMFDKLGW------------------------
>UniRef50_C7R188(132-344:362) Pseudouridine synthase n=3 Tax=Actinomycetales RepID=C7R188_JONDD   E=5e-32 s/c=0.66 id=27% cov=82%
--DVLFEDDDLYVIDKPHFLASTPKGRYVTETALV-RLRKDTGNPELSPAHRLDRLTAGVLVFTKRRELRGAYQELFAQRQVTKVYQAVAPTNPAVD-LPATVRSRIVKEHGIMRAHTMPGEPNTETLVTLTDTATLP-AGHDVAVQDVGLYTLYPHTGKTHQLRIHMASLGLGIVYDNYYPDFYHVESDDYRHPLQ---LLSSQLAFTDPLSGVQRDFRS---------------------------------------
>UniRef50_Q6MKN0(84-282:283) Putative RNA pseudouridylate synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MKN0_BDEBA  E=8e-32 s/c=0.70 id=28% cov=77%
---IVFENEHFVVTNKISGLPVHASVDNLHENL--QSYLQQTLHQNVYVTHRLDVPTRGLIVYAKSPEFQTEFNKLLIAREMNKIYRARVQGHSLSTGLLQHYM--EPSPRAPKVVSKELQPKWQECLLEILEFSKL--------ENEMSEVRIKLHTGRTHQIRAQLSAEGHPIVGDVAYGAVKVWDE-------ERIELEACELAFTNPLTGEHHEFK----------------------------------------
>UniRef50_Q9ZKP5(58-241:242) Uncharacterized RNA pseudouridine synthase jhp_0890 n=35 Tax=Campylobacterales RepID=Y956_HELPJ  E=9e-32 s/c=0.76 id=36% cov=65%
---VIFEDENILALFKPPFI-------------ESYDLVSFFKG--WALLHRLDKETSGVILLVKeNSEFHLKAKKAFKDRAVKKEYLAIVQGIIEEEREINAPILTI--KTTKAFSKISKKGQEAVTIITPLKII-----------NKKTLLKVGIKTGRTHQIRVHLKHINHPIIGDTLYNN--------EPSSAKRLMLHAHKIAL----------------------------------------------------
>UniRef50_D1BPK0(129-372:372) Pseudouridine synthase n=3 Tax=Veillonella RepID=D1BPK0_VEIPT   E=1e-31 s/c=0.57 id=27% cov=81%
-LSVLYEDEDLFIVDKPSGVTVNSKDRLSLANGVAHYFKEHGIKRKVRFLNRLDRDTTGCIVIAKSGLAQSLYQQQMDDNTFEKWYMATVEGIVEADEDTLVFPMERSADGIHYEVNAK--GKETRTDFSVLCRhssqpvdnsvnksensvdiglknvdielvdvdknnLNVDKTVYKSNKCGYTEVLVRLYTGKTHQIRVAFSHIGHPLVGDTLYGAQPTGQPFQ---------LRAQKVVFTHIRTGEHITVMA---------------------------------------
>UniRef50_A8EW74(60-246:251) Pseudouridine synthase n=4 Tax=Epsilonproteobacteria RepID=A8EW74_ARCB4  E=1e-31 s/c=0.74 id=27% cov=65%
-VKVIFEDKDILVVDKPAFLT--------------ADEVCKKF-ENAILLNRLDKETSGVMMFAKNEEFQKKAIKEFQANRVYKEYVAIVEGKVVDEIEIDKPILTTKDRGMAKSKIDVKRGKPAKSTVYPL-----------LVEGNKSKIKVVIESGRTHQIRVHLNSVGLPIIGDAIYGRVSSN--------VNRVLLHS---------------------------------------------------------
>UniRef50_C0QC81(75-291:295) Pseudouridine synthase n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QC81_DESAH  E=2e-31 s/c=0.64 id=32% cov=70%
---------------KPSGMSVHNHPGSDLLCVLerqiradedLMVALGAQEGFQIHPVHRLDQETSGLILVATDPDRLRYLSNLFQQGAVQKHYIALVHGNFDPP--CDPFQVWDTPLSKQAGGRTDPRGKgkrvRSETRYRIMDQ-----------SPHYTLLEIELVTGRKHQIRRHAKLAGHPVTGDTRYGSKRSVEFLRENHAYDRLGLHSFKIEFI---------------------------------------------------
>UniRef50_D2VR13(121-321:483) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VR13_NAEGR   E=3e-31 s/c=0.68 id=25% cov=68%
-IPILYDESDLLVVDKPASFPIHPCGRYRKNSLT--YILEENGYGTLHVVHRLDHSTSGVLVLAKNKKVSGEIVEMIKTREkaIGKYYLAVVKGKWKGEYE-VSGLVKDLNNsfvkceKKVYCKNHKNGTWSADDELGTFEAITLFSGIVYNKEKDISLIMCKPITGRTHQIRIHLESIGNPIINDFFY-------------------------------------------------------------------------------
>UniRef50_A8XVV3(154-332:438) Putative uncharacterized protein n=2 Tax=root RepID=A8XVV3_CAEBR   E=4e-31 s/c=0.77 id=28% cov=64%
-IRIISETDDLLVIEKPPSLPVHTCGQYAIHT-VLGQLRENEEKTGLRVLHRLDRATSGVLLFAKNYETDLEFKTTLKQGEWSKEYVCKVDGVFPDeEQVCEQPIGPLVISMGIQCVRPD--GKEAKSTFRKLWS-----------DGTHSVVQVHIETGRTHQIRVHSQFLGYPIVGDQLY-------------------------------------------------------------------------------
>UniRef50_A8NJ16(2-251:268) Predicted protein n=1 Tax=Coprinopsis cinerea okayama7#130 RepID=A8NJ16_COPC7  E=6e-31 s/c=0.54 id=29% cov=82%
--------------NKPAGLVSQLGRqlpemktRDTLDKVLKQIERRLELKEALRPLHRLDTATTGCLAFATTQTSARSLSKQFAQGQVEKSYLALVSGGKETFPGTSGRIDTPIKYQDGYFDGLGTGGKLSLTEWSLLAS---------SPVLPISLVRLNLLTGNKHQLRIHMAkKLGAPILGDDRYSSSKVASKLLSEGRIKPnLYLHASDIAFVRyrqrgPQKRFRLGITAPLPAHFVEACKAF--------------------------
>UniRef50_C4XWV4(146-316:432) Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC 42720 RepID=C4XWV4_CLAL4  E=1e-30 s/c=0.79 id=30% cov=64%
---VLYEDENILVVNKPAGVPTHPNGIFRRNSLT--EIVRFELGVSVYPCHRLDKGTSGVLVLAKT-KTGKMLQEvlQNKKSHVEKWYVARVRGKFPFaSCSYTSPVFSINTAGTGYLNIPNAERVPATssTHFKMVSY---------SPELDESIVFCRPISGKMHQIRVHLRNMGYPISNDPLY-------------------------------------------------------------------------------
>UniRef50_UPI00005230E6(163-430:494) PREDICTED: similar to RNA pseudouridylate synthase domain containing 4 n=1 Tax=Ciona intestinalis RepID=UPI00005230E6  E=2e-30 s/c=0.50 id=32% cov=65%
--NVIYADNKLVIFNKPYGLPMHDGDGTKQTVKNVLPFLSKmvygiNTDIPLHLCHRLDKNTTGITICSTDAEMADYVMGLFRQRRVLRKYLAVVVGEPePMKGVVDMPMSesivsatKSTKRHSRMIIKPDvryddatgkeyplrnAGGHTAITHYRTIDT-----------TGDLSLVELQPQTTVKHQLRVHMAdGLSCPILGDHKY-------------------------------------------------------------------------------
>UniRef50_Q6BK17(124-311:433) DEHA2F25652p n=3 Tax=Saccharomycetaceae RepID=Q6BK17_DEBHA   E=3e-30 s/c=0.71 id=27% cov=66%
-LSIIFENDEMLVIDKPAGIPTHPKGNYRYNSITELVK-HDLNLENVWPCHRLDKVTSGILILGTTKQGSKIYSTIInnERDRISKQYVARVMGeFPKDEFVMNCPIFLVNTSGGYIMPSNSRNvPKNSTTIFRRLNYNKELNQ---------SIVLCKPITGRMHQIRIHLRNTGHPIVNDYEY-------------------------------------------------------------------------------
>UniRef50_Q00YR3(57-255:300) Probable pseudouridine synthase (ISS) n=1 Tax=Ostreococcus tauri RepID=Q00YR3_OSTTA  E=6e-30 s/c=0.67 id=28% cov=75%
---VLHESEAVVIVNKPRGMSFH-----SEFAPGALARLRTQMGERtaVMSVHRLDKPTSGILVFAKNARARDALSKAFEEREIVKYYVGMSNRKPRKKMGTVRGDMTRSRRKAWMLTSTTES--PAETKFVSFGARGMGERALR-------MFVFRPMTGKTHQLRVAAKSLGSPLLGDDTYGGERD---------VDRTYLHACAIRIPKSVLGETIQI-----------------------------------------
>UniRef50_Q8SVK5(85-308:318) Putative uncharacterized protein ECU05_0680 n=1 Tax=Encephalitozoon cuniculi RepID=Q8SVK5_ENCCU  E=1e-29 s/c=0.59 id=28% cov=62%
---VIKEEGDYIVVNKPPGIPCHPTGGYREYCVTKAL----FGDEKVACINRLDMPVSGVLILAVRN--HSKCLEAI--RDAKKIYVAKVYGMFPDKVDVDKRIGCTEGRYRH----VNAGGKACLTLFRRLEYRD-----------GYSLVECRPVTGRTHQIRIHLQSIGFPIANDIMYGDGE---------------------------------------------------------------------------
>UniRef50_C1MPG5(72-341:348) RNA pseudouridylate synthase n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MPG5_9CHLO  E=3e-29 s/c=0.49 id=29% cov=82%
----------FVVVRKPAGVYV-------DDVLAALERdasasasaSPSPSPRRLHLAHRLDRDTSGCLVVATSTRACAALTRAFADGKVRKEYLAHCssaaasssseprepdpspspsldgarpltlrtgHGRSRNGLWRVYPLSDVGRALPRDPGRKTTLVKIAETSLVVVATAAARGGGGGGERSRCAYVRATPTTGRTHQIRLHCAHAGAAIVGDVKYGGPRvveeeeeeeekeketQEDDALIDTRFDGFRLHAAKIAFPHPtREGQTVEVECPPPGWWREA------------------------------
>UniRef50_C5C8S8(92-340:348) Pseudouridine synthase n=1 Tax=Micrococcus luteus NCTC 2665 RepID=C5C8S8_MICLC  E=4e-29 s/c=0.52 id=26% cov=82%
----LHRDEHLVVIHKPHFLSTTPGGRFVQETALVQ-LRNELGLDDLVPLHRLDRATAGVVMFSANPATRGAYHLLFERRAVAKTYEAVAllpdapddgargPGTPADPVLGRFPLtvrsrirkdkgvlrsvveeippaasgRRAGAPVRTRRSNRPHAGANAESRVELLGV---GVSAGTLAGRRVAHLRLTPRTGRTHQLRIHLAALGLGIAFDPFYPDLLDLAPDDVT---QPLQLLSRSLRFTDPVTGEEREFTSP--------------------------------------
>UniRef50_Q2SKD2(13-188:231) Pseudouridylate synthases, 23S RNA-specific n=3 Tax=Proteobacteria RepID=Q2SKD2_HAHCH  E=5e-29 s/c=0.74 id=30% cov=68%
--------DDLLVVDKAPGISFHDEEGQPGLCSCVADTL----GIRVYPVHRLDKVTSGLLLLPKTPALARELTEQFSLRQVEKYYLALSAHKPQKKQGKIIGDMEKARAGAWKLTAGREN--PAVTQF---------FSHSLQPGVRAFMVR--PLTGKTHQIRVALKSVSAPIAGDSLYGG-------RANKEFDRTYLHAYGVRF----------------------------------------------------
>UniRef50_C8RSX9(70-311:313) Pseudouridylate synthase n=2 Tax=Corynebacterium jeikeium RepID=C8RSX9_CORJE  E=1e-28 s/c=0.53 id=26% cov=85%
-IAVLHQDADIVVVDKPPFLATLPRGQHITETALVKARVQLGI-PELSPSHRLDRLTRGVLLMTARPEIRGAYQTMFERRIPHKVYEALTPlpeeapfapiAPLADWRSWDPPTPERPWRLEHSMSKTRGHLSTILTDGSPNALTLVTGLRTEWREGRKILVwRLEPHTGKTHQLRVVLRSLGLPILNDPLYTELTDAALFSIDAPTPRpvyvededfsspMGLIAKELRFPDPLSGQERKFVS---------------------------------------
>UniRef50_Q5XET6(181-467:478) RNA pseudourine synthase 3, mitochondrial n=10 Tax=Magnoliophyta RepID=PUS3_ARATH  E=4e-28 s/c=0.44 id=31% cov=65%
---VRFKDSAIIVLNKPPKLPVKGNvPIHNSMDALAAAALSFGNDEGPRLVHRLDRETSGLLVMGRTKESIDYLHSVFSDYKgrnssckawnkaceaMYQQYWALVIGSPKeKEGLISAPLSKVLLDDGKTDRVVLAQGsgfeasQDAITEYKVL----------GPKINGCSWVELRPITSRKHQLRVHCAeALGTPIVGDYKYG------------------------------------------------------------------------------
>UniRef50_B8BWY4(2-174:175) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BWY4_THAPS  E=7e-28 s/c=0.73 id=35% cov=60%
------------------------------------------------VVHRLDRDTSGVFLLARNDEALKTLHDDFKDKtrgRVTKRYVALVCGHWnsdnascvadrmtTDEGEIDLPLVRDIENPPFMRV----------------------ATTGNEIKLPVTRVELQPITGRTHQLRVHCAAMGYPIVGDSIYGYGGEGSPRegiEMDEDECLLCLHAQRLTIFHPLTKAPMMFECSPP------------------------------------
>UniRef50_B6KRF5(4748-5011:6535) RNA pseudouridine synthase domain containing protein n=5 Tax=Eukaryota RepID=B6KRF5_TOXGO  E=8e-28 s/c=0.48 id=27% cov=72%
---------------------------------------------ECGLCHRTDLETSGSLLIAKTRRARESIFEQFRKRLVHKEYLLLCHGRLdKLHARIDHPIAtRDFDSSRSKshfseVVGPDEGGDEALTEYQVVRVFGVRQPVHRKIqaamsvaariasspssssssssapsdrargsgaaaagakaagsgkgspvsgtaakkdfsySQEFSFCRVRIHTGRTHQIRVHFRHIGHPLVGDTKYCDLY--KCTVDRSWCARMFLHSAVLEFDNPDKTETqhVRVVCPLATELLAALE----------------------------
>UniRef50_B9Z169(1-216:229) Pseudouridine synthase n=1 Tax=Lutiella nitroferrum 2002 RepID=B9Z169_9NEIS  E=2e-27 s/c=0.58 id=27% cov=81%
MFDLIATDPRFYVIAKHPGVSFHR-QGDEAGLMEALRA--QLADDALWPVHRLDRLTSGLLLVARSAEVASRLAEAFAAREIEKYYLALSDRKPQKKQGLVRGDMVKGRGGAWRLLPSSAN--PAITQF-----------FSFSLAPGLRLFILRPHSGKTHQLRVALKSLSAPILGDELYGG----------TPSDRGYLHAYSLAF-H-LDGERFHFICPPrhgahfnAEALQAALQKPEWQ-----------------------
>UniRef50_A8H661(108-295:305) Pseudouridine synthase n=7 Tax=Shewanella RepID=A8H661_SHEPA   E=4e-27 s/c=0.65 id=28% cov=73%
--ELLFDEEQYSVWYKPFGMRCQGSKWSDHTTINRFIETQLTPPRNAYIIHRLDLAATGLIVLGHTKKVTAAIAQLFETRALDKFYQVIVEGKFPEGQV---------------TINTDVDNKKALSHAHILEY---------NSELNQSKVQVKIESGRKHQIRIHMASLGHPVIGDRQHGNG--------SDLTPNLQLTSCHLSFVCPVTGEDKVFELP--------------------------------------
>UniRef50_Q98R93(81-280:282) RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE C (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) n=1 Tax=Mycoplasma pulmonis RepID=Q98R93_MYCPU  E=5e-27 s/c=0.61 id=23% cov=72%
-FNVIFEDQNILVINKQAGVSMHSDENSLDKQVLSYLNFKQVDSFVPSSIGRLDKVTSGVVVYAKNYSILKTLK---SNEHLRKTYVFMSNITLEPNQKIEHVFYHKYNPIKKKAELFKEN---------VEESKITKTLLYKVKNNNYA----ELITGRKHQIRATLSKLGFPIFGDVKYGGKKD----------KRVYLHSYKIKF-HSLKGE---------------------------------------------
>UniRef50_C5LRC8(202-400:439) Ribosomal pseudouridine synthase, putative n=2 Tax=Perkinsus marinus ATCC 50983 RepID=C5LRC8_9ALVE  E=7e-27 s/c=0.62 id=25% cov=70%
-----------------------------------------------GILHRLDVGTSGPLLLAHSYKGFYMGRLVFCSHQIDKEYVALVKGHMGTVGKNIVISDRikilkstlDNGQSYSTTCVVAPDGKPSLTEVVPVAHY------NDGSGEEYSLVLVKLHTGRTHQIRVHMAYIGHPLVCDPKYGNPTDPEAAKAVCAIDRLwcprtFLHSYRLCYNQPMDvvdekDATVDVYVPMPLDLRLALAKL--------------------------
>UniRef50_B9QFU8(2008-2239:2273) RNA pseudouridylate synthase domain-containing protein, putative n=4 Tax=Toxoplasma gondii RepID=B9QFU8_TOXGO  E=3e-26 s/c=0.52 id=24% cov=88%
-------------------LAVTQREREHRKREEERLALLFDASHQFGIGHRLDTPTSGPLLVAKSYAGLAFLRAQLASWRPKKVYLALVFGAVPLREKVRLVHPLRPTFEAGKTGKKEMEVANTV-DAKIALSFLSGITHYSYGGRDFTLCRVEPVTGRTHQIRAQLAHIGHPIVADPIYVNDPADRALGRSLS-DRVFLHCVSLSFLNILENENRTGTSDFsPED------QFDEERTGNRKERPPLQAdPSERP-----
>UniRef50_UPI00019264FF(32-284:329) PREDICTED: similar to RNA pseudouridylate synthase domain containing 4 n=1 Tax=Hydra magnipapillata RepID=UPI00019264FF  E=6e-26 s/c=0.47 id=28% cov=85%
----LYMKDGLLAIHKPYGIPVHGGPKIKLSIADFLPALEQKHGLlagSLELAHRLDKNTSGVLLLTYKKEMAKYLADLHENRQIEKSYLAILLGNVSRvTGVLNGELHETLRNGQFKQTINEISINKSsvETNYTILDSNQDT----------CMLCLFKTFTGNKHQIRVHAYElLKCPILGDHRYHANKGPQTLPIRLiqmlrmrgvkneetgsskirpwqrGLLPMHLLTKSIRIPGLDGSKDLTIETSIPPYFQQTMDHL--------------------------
>UniRef50_B7FYH0(89-308:311) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FYH0_PHATR  E=7e-26 s/c=0.55 id=32% cov=77%
---ILARTDRYVVVAKPPTVVCHhsewtGSRSDPFQIPMLQRTREAMGGNCVNLVHRLNWGCSGCLLLTYAADTADAeiyipnttatLIASMKETASLKTYLALVRG----EGLLQGRDFKQEGWFKVDRPIKNEKGilNNATTWFRFVA--GQDNDSGRINQPRASLVLARPETGRWHQIRRHLNGLSHPILGDTSHGNSHVNREWRDLRGMPaqRTCLHLARLQL----------------------------------------------------
>UniRef50_B7XJU4(78-324:331) Diaminohydroxyphosphoribosylaminopyrimidine deaminase n=1 Tax=Enterocytozoon bieneusi H348 RepID=B7XJU4_ENTBH  E=1e-25 s/c=0.48 id=27% cov=62%
-IPTIYIDDEITVVNKPFGIPCHPVGAYHYYTVT----KTIFKNKPVGCVNRLDIPVSGVLIIntCNQKRIHEYLLNS------KKIYIAkvIGQFIFSDEQLHKLGIEKRISNGKSiiivnksllldpktKKQKISDDGKFAETHFELVSY-----------QNQYSMIKCYPITGRTHQIRVHLAYIGFPILYDTLYG------------------------------------------------------------------------------
>UniRef50_Q6KHG9(110-310:314) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Mycoplasma mobile RepID=Q6KHG9_MYCMO  E=1e-25 s/c=0.59 id=26% cov=69%
-LEIIFENLDILIINKPNNLIMHSSKNSLDEQVLNYLNYVKIDSFVPTHIGRLDKETSGLVVYAKNYKTLIELLD--KQSDFEKIYTFIPFCNLsEKDVLVTVNISEDEINKKMQISNE---GKKSITRI--------------FYDGNSQRYYAQILTGRKHQIRLVLAdFLKCPILGERKYANLTKD---------KRLFLHSYKLTF----------------------------------------------------
>UniRef50_Q6F0Q2(103-302:323) 23S rRNA pseudouridine synthase n=1 Tax=Mesoplasma florum RepID=Q6F0Q2_MESFL  E=7e-24 s/c=0.56 id=22% cov=66%
-IDVIYEDSNLLIVKKPYNVEVHSPVKTSMDDIVknylfdtNQYNPSEENSYVISHIHRLDKLTSGLIMYAKNKQTHDIMVEAIQDKeKIEKYYRCRIDVPVTESLIAKGWIKYDPIIQKSVFSEEfRSDYKEATTIFNVVS---------LDVTNEQTELEVQILTGRKHQIRATLEYYGASIINDSRY-------------------------------------------------------------------------------
>UniRef50_C4XKF0(88-262:290) Putative pseudouridine synthase n=1 Tax=Desulfovibrio magneticus RS-1 RepID=C4XKF0_DESMR  E=1e-23 s/c=0.64 id=27% cov=67%
---------DYVLLNKPSGL--HSAALAQGGGESVEALLPDIFPGRPsFLLSRLDSLTTGLLPAAFSPEAAATYRDMEESGEVDKTYLAVGHGEP--DVTYFRCDGELDAADRKKTRVLDRA---------TIDSLRMTEVEALETRGGVTLFRCTIKKGARHQIRTHLAWAGHPLVGDPLYGQGEG----------ERLFLHCA--------------------------------------------------------
>UniRef50_C6M7K6(1-114:125) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Neisseria sicca ATCC 29256 RepID=C6M7K6_NEISI  E=1e-23 s/c=0.98 id=36% cov=44%
------------------------------------------------------------------------------------------------------------------MVRVSEEGQSAHTIFRVLNRF-SDDLLHQVGLSHLTLVQATLKTGRTHQIRVHLQSQHCPIAGDERYGDYQANKRL-QKLGLKRMFLHAAELHLDHPLTGEKLILKAPLPQDLAQ-------------------------------
>UniRef50_P45614(82-277:302) Uncharacterized RNA pseudouridine synthase MCAP_0714 n=3 Tax=Mycoplasma mycoides group RepID=Y714_MYCCT  E=6e-23 s/c=0.56 id=25% cov=66%
-LDIVYEDNNILIVNKPNNLEMH-SIYNLCLDDMVKSYLVDKKEYDIYLensfvishVHRLDKLTSGLVIYAKNKISSIILTNAFKTKdQINKYYYALTSYDWNLNDFLQVNGYINYNSNTQKADfslVEKNNYKYCQTEFKLVNKN---------------LILVKLITGKKHQIRSVLSFYNNPILNDFRYNGKKEN-------------------------------------------------------------------------
>UniRef50_A8NRI8(175-419:422) RNA pseudouridylate synthase family protein n=1 Tax=Brugia malayi RepID=A8NRI8_BRUMA  E=4e-22 s/c=0.44 id=25% cov=64%
---IIYEDEELIAFNKPYQVACSNAPSNQAELLRILPQLSSRITPHmncLRIVKSIGKSVTGVTLFAKNQNVQEKIKTLYENGLIEQCYRVITNMAPAHqEATINIPLMLPLSANSSNEITP---FLEASTYYRVLRH---------DPKNHTSYMECVVNCDVPEQIRAHLGiGIACPIIGDIKY-------------------------------------------------------------------------------
>UniRef50_C5J5W4(82-261:284) Ribosomal large subunit pseudouridine synthase n=1 Tax=Mycoplasma conjunctivae HRC/581 RepID=C5J5W4_MYCCR  E=8e-22 s/c=0.59 id=25% cov=63%
-FDILYEDSNILVVIKPRQTAMHSHKFSLDNQVHKYLNIKMADIFKPAHIGRLDKDTTGIVIYAKNYQTALEMNK--KQHFFVKRYVFKSDIDLKEKVDVKLWIKKNDDlKKMEVSQEKTQNSQLAITSLFLIGNNKI----------------AQLQTGKKHQIRLTLSHLGYPIYGDQKY-------------------------------------------------------------------------------
>UniRef50_B8P3B5(60-264:348) Predicted protein n=1 Tax=Postia placenta Mad-698-R RepID=B8P3B5_POSPM  E=2e-21 s/c=0.51 id=33% cov=61%
----LYVDRGLLLVNKPSGLVCQYNRKDDReqnahsdfNDFTDDLKRQLSLDADLLPLHRLDKATTGALAFALTHSHAQDLAEQFNAHTVKKSYLAIVRGGTASFPNRTGNIRGVLYTTNGRVSSEAQGqwEKRAITEtdWEVLAS---------SPVAPLSLVRLSPFTGHKHQLRVHMAKI-----------------------------------------------------------------------------------------
>UniRef50_B6AH65(140-389:527) RNA pseudouridylate synthase family protein n=1 Tax=Cryptosporidium muris RN66 RepID=B6AH65_9CRYT  E=2e-21 s/c=0.42 id=23% cov=68%
---ILYNNKHFLAVYKPYGIPCHPQGRFHKLSLTNIVMSKYFRSEteviidnkaasriinddklYAHPINRLDRVTSGLVILSKNCDSTRLLSKVISKSH--KYYLAHVEGDFSSLEHVDigklfkstqlvkiqnlemglninfgikceapLEIIKDRVGDSLMTKVSFENGKSALTWFFPLKIEYLSQEDRKKIKldqvnfesinichKPNSYVLCKPVTGRTHQIRAHLQYLGFPVTLDHLY-------------------------------------------------------------------------------
>UniRef50_Q750S3(6-246:260) Pseudouridylate synthase PUS5 n=1 Tax=Eremothecium gossypii RepID=PUS5_ASHGO  E=6e-21 s/c=0.43 id=26% cov=85%
-VPILHEHKHYYIVNKVHGIVCQPPdlrtwyKYHDYEPPVLLDLLRKQhpnfGGEVWRTVHRLDEPVTGGVLVSRNKRAAAMFSRSLalggnRGFPLTRRYVALLA---------------REAKGLPSEGRITMG--DMITDYKRLEND---------------LVLLQLQTGRKHQIRKQMAQVfGQPVVNDKMYGGDSVDGIVDNLIGLHSAFigaqcgLQARTYLIPIPRTQDAFKL-------WDKYIDEQGGFIPSVQKELRDFSLPSKLENTIT-
>UniRef50_C1MVV0(139-354:539) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MVV0_9CHLO  E=7e-20 s/c=0.46 id=31% cov=68%
---VLTEDERVVIVDKPPGLPtlagVGPGVAGENNAVAVLRRLRASasasakrkreesddggggggggddDDAPLFAVNRIDKPVSGVWILAKgsrlSARARDALHKGAARGETRKTYVALvkgrvevgGGGAGGGGFVVDAPLRKDERGLA---VVGGDGAKPAATRVVPLAVVAVPSKGGGGEKEALTLAAVALEkSGRYHQIRAHLAHVGHPIVFDRDY-------------------------------------------------------------------------------
>UniRef50_Q313X0(85-274:305) Pseudouridylate synthases 23S RNA-specific-like n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. G20 RepID=Q313X0_DESDG  E=8e-20 s/c=0.52 id=27% cov=68%
--EVLCRTADYAAIFKPEGLHSARIAASPAPSVEDQLDSLFAGETPPVLVNRLDRPTSGMVLAAFGSHAAEAFRKFEQAGQVEKLYLAVVLGHMKAPVACRNELNMQNRQVTTVLPHEAQDPLRHTT---VLPLRALPAES--MDGQKTTLVLAAIHRGARHQIRAHLAHAGHPIAGDCVYG------------------------------------------------------------------------------
>UniRef50_C2HWY8(14-118:177) Pseudouridine synthase n=2 Tax=Vibrio cholerae RepID=C2HWY8_VIBCH   E=1e-19 s/c=0.94 id=29% cov=40%
-IDVIYEDEHIIAANKPSGLLSVPGRPVEHYDSMWARLV--DYCPDVKVVHRLDMSTSGLILFAKGKHMESALKKQFQYRLTHKIYYARVWGVMEQDeGEVNLPIV-----------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2VJR9(52-262:301) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VJR9_NAEGR   E=1e-18 s/c=0.45 id=32% cov=60%
--------------------------------------------------HRLDMATSGVLCLSMTRESCACLSTSFEDKTSRKFYLALLSGDVnleelkmneklrnnvkvvnendcskiiitsfigRDDGGNNENEEYDPTGRGFVMKQTLEKPIEDLSKYKTKQERQQHQfregtsemiilSYGQVENKPVTKVLLRPLSGRKHQLRLHSLLLGHAIIGDEMYG---------ENDGFSRLMLHAYSLQI--PIDKEYL-------------------------------------------
>UniRef50_C4R5D7(1-229:249) Putative uncharacterized protein n=1 Tax=Pichia pastoris GS115 RepID=C4R5D7_PICPG  E=2e-18 s/c=0.41 id=20% cov=68%
MIRPFFEGPGFLVINKPPGIYTQPPSfrqGNRDKSNELLPLLEKQLQTTLRQVQRLDYETTGGLVVSTNKYTARMFHRNMQalsnnildgrhrssnkGYILTKRYIALLN-KPVTSIYEQLPKTSDGWRLLETQDIDESNSSSKLLLSKV-----RTIESCRPMHDKFPLM-FELITGRKHQIRRQIKQVfGTTIVNDVKYG------------------------------------------------------------------------------
>UniRef50_C5YIB1(182-428:439) Putative uncharacterized protein Sb07g027030 n=1 Tax=Sorghum bicolor RepID=C5YIB1_SORBI  E=9e-18 s/c=0.38 id=32% cov=54%
---VIHRDSAILVLNKPPkvpmkgHLPVHNSM---DVLAAAALSYGNKEGPKLTW-----------------NKACEAYVQ---------KYWALVIGTPKeREGVICAPISKVllDDGKAERVILAHPSGidgaQEAITEYRVM----------GPTINGCSWIELRPLTGRKHQLRVHCAeALGTPIVGDYKYG------------------------------------------------------------------------------
>UniRef50_C7ICF2(65-203:235) Pseudouridine synthase n=1 Tax=Clostridium papyrosolvens DSM 2782 RepID=C7ICF2_9CLOT  E=5e-17 s/c=0.65 id=22% cov=53%
-----------IMLNKPVGYVS--TSKDQFGRPAVIDLVKD-AGKRLYPVGRLDYDTSGLILLTNDGDFTYRLTH--PKHEVNKVYEAVISGFPDKNEITRFETGLKIDDY-----------QTSPAEFEVL-----------NKKGINTLVRITIHEGKNRQVRKMCEAIGHKVL------------------------------------------------------------------------------------
>UniRef50_C7MNA2(113-251:296) Pseudouridine synthase n=1 Tax=Cryptobacterium curtum DSM 15641 RepID=C7MNA2_CRYCD  E=2e-16 s/c=0.64 id=26% cov=54%
-----------LALNKPAGIIT--TMKDLRGRRCVADIMPTEQYPGLFPIGRLDQDTTGLLLFSTDGNLGNALLH--PSHGVSKVYRATIEGSIGQAALEQLASGILLD-----------DGMTAPARVSVVQ-----------AGKKHSVIELELHEGRKHQVKRMCQAVGHPVV------------------------------------------------------------------------------------
>UniRef50_C8WAL4(71-228:279) Pseudouridine synthase n=7 Tax=Coriobacteriaceae RepID=C8WAL4_ATOPD   E=9e-16 s/c=0.55 id=22% cov=57%
-----------LMLNKPAGYLT--TMKDPQGRPTIVDMVPTDTYPGLFPVGRLDMDTTGLLFFTTDGQMAQELLH--PSKHVWKHYVAHVVGTPTEEQL-----------NRLREGIELEDGPAAPAEVEIISDDVKMKNLLAPQGLGKTgggepnaLVSVTIREGRKHQVKKMLLAIHH---------------------------------------------------------------------------------------
>UniRef50_B1C6T1(70-205:238) Pseudouridine synthase n=2 Tax=Clostridiales RepID=B1C6T1_9FIRM   E=1e-15 s/c=0.63 id=23% cov=53%
-------------LNKPQGVISASKSKYGEETVVDLLGKKEH---RLFPVGRLDKDTTGLIILTNDGDFAYKLTH--PKYEKEKTYEALVKGKVDSKSL-----------DKLKQGVVIDGKKTSRAKVRLVKMIGVN-----------SLVEITLIEGRKRQVKKMCEKVGHKVI------------------------------------------------------------------------------------
>UniRef50_D2B9T7(446-584:621) Pseudouridine synthase n=18 Tax=Actinobacteria (class) RepID=D2B9T7_STRRD  E=2e-15 s/c=0.62 id=30% cov=53%
-----------LAINKPIGVVS--TMSDPDGRPSLADFVADRT-ERLFHVGRLDTETEGLILLTNDGELANRLTH--PSYGVQKKYWAKVPGR----------IERDLGRRLKKGIELEDGIAKA------------DSFTLVQEHGQQALVEVVLHEGRKHIVRRMLEEVGHPVI------------------------------------------------------------------------------------
>UniRef50_D0N5S3(116-199:214) Putative uncharacterized protein n=1 Tax=Phytophthora infestans T30-4 RepID=D0N5S3_PHYIN  E=2e-15 s/c=1.02 id=29% cov=33%
---VVYQDAQFVVLNKPHGLAVQDGS---TLTESLALYLPWIAEQQLRLVHRLDKETSGVLVLARSRLAAAKFSKLLRNGAVYKTYEALV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1M2R1(1-176:186) Putative pseudouridine synthase (Fragment) n=1 Tax=Arcanobacterium pyogenes RepID=Q1M2R1_9ACTO  E=5e-15 s/c=0.48 id=27% cov=56%
-------------------------------------------------------------------------QDMFAARKVTKIYEAVARcvdlgalaGNLPgvakaeagHLGEWVRVDLRLAREPGAIAVHVAEGEPNAVTYIRKVRQLRATPELVPAAADGeatappaLALYELRPITGRLHQLRATLNYLGAPIAGDPLYPKVLSLEDTAAR-SFPTQLL-AAQLSFVDPVDGEQVHI-----------------------------------------
>UniRef50_UPI0001BCEF2E(57-203:296) pseudouridine synthase n=1 Tax=Selenomonas noxia ATCC 43541 RepID=UPI0001BCEF2E  E=6e-15 s/c=0.57 id=27% cov=55%
----IHSDEkrFYILLNKPRGYLS--TARDDRGRKTVLDLLPD-FPARLYPVGRLDADTEGVLLITNDGAITQGLLH--PRFEIDKVYHAEVAGPVTEGGLT-----------RLRRGILLEDGMTASAKLRILR-----------ADKGYTVVETIIHEGRNRQVRRMFAAIGC---------------------------------------------------------------------------------------
>UniRef50_B3GZS7(37-191:232) Pseudouridine synthase n=10 Tax=Pasteurellaceae RepID=B3GZS7_ACTP7   E=9e-15 s/c=0.54 id=23% cov=60%
-----FEDTVVVLFNKPFDVLTQFT--DEQGRQTLKDFI---PIPQIYPVGRLDRDSEGLLLLTNNGEIQHRLAN--PKFEKQKTYLAQVEGIP-----QAADLAKLEKGVELKDGLTKPAKAKAISA--PNYEWQTAPKIRERKTIPTSWIELKIHEGKNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_D0NJP5(65-425:458) RNA pseudouridylate synthase-like protein n=1 Tax=Phytophthora infestans T30-4 RepID=D0NJP5_PHYIN  E=1e-14 s/c=0.23 id=30% cov=75%
-LRVLSRDEHFVVLNKGPDVRM---DGAFDVTLEKALARDFPQVEKFRWIHQLDFATSGVLVVGVNKDATATGCRLFREKQVQKEYLAVVRGHLPFNpaesvdtaalpakactfsklglliqdmeemerlrnqqrgsrahqktpgyprgvrhgpnlftmeqaqllpeareltpaelaftkmtwhdltkeekgaytekakadkrrflKEFSEFLNQEKIRLARKRKYESFDGEDSEeanepvayvfdapviephrstgvfrmlvgtetdTAAKQSTTMCFVLGHAIYKGEPVTKVLLRPLNGRRHQLRLHMAHHGFPIAGDVTYGSQEDE--------APRMMLHAWRI------------------------------------------------------
>UniRef50_A9GX03(64-202:399) Pseudouridine synthase n=2 Tax=Bacteria RepID=A9GX03_SORC5   E=1e-13 s/c=0.57 id=28% cov=50%
-----------VALHKPRNVVS--TLRDPEGRPTVADHVR-GTGARLYPVGRLDFATSGILLMTNDGDFANALLH--PRGGVPKTYVLKVQGVMSDD---------DLTPWREGIRLEDGVTLPA--EARLLRH-----------EGDKTWLEVTLREGRNQQIRR----------------------------------------------------------------------------------------------
>UniRef50_B3E7C4(64-203:274) Pseudouridine synthase n=6 Tax=Desulfuromonadales RepID=B3E7C4_GEOLS  E=2e-13 s/c=0.56 id=26% cov=53%
---------YYVLLHKPAGYVT--SLKDPQGRQLVTELVKD-VGERLFPVGRLDYNSEGLLLLTNDGAWANRLMH--PRHQVDKEYHVRVRGKIDPQQIKKLADG-----------VELEDGPTGATTVRLLKNDQSND-----------WLSVTIREGRNRQVRRMCAAVG----------------------------------------------------------------------------------------
>UniRef50_A2RP35(139-324:328) Pseudouridine synthase n=172 Tax=Firmicutes RepID=A2RP35_LACLM   E=2e-13 s/c=0.42 id=30% cov=35%
---ILdYQEYYYYLLNKPQGVVS--ATKDNVFKTVVQLLSEKDFRKDIFPVGRLDKNTEGLLILTNDGALGHDLTQ--PKKHVEKEYFARIDGKVTDE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9KIR7(67-208:250) Pseudouridine synthase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KIR7_9FIRM  E=8e-13 s/c=0.54 id=25% cov=55%
-----------LLLNKPKGYLS--TAKDDRGRRTVLDLL-PEVRERVYPVGRLDNNTEGLLLITNDGALMNGLLH--PRFEVEKTYHAGVTGKLTEEKLQMLRDGLLL-----------EDGMTAPAKVSLL-----PEREPGERVRGLTRAAITIHEGRNRQVRRMFAAVGC---------------------------------------------------------------------------------------
>UniRef50_Q1D5Q2(63-204:745) Pseudouridine synthase n=6 Tax=Bacteria RepID=Q1D5Q2_MYXXD   E=1e-12 s/c=0.54 id=20% cov=55%
------ESSYFL-LYKPVGVVT--TLSDPQGRPTVANYVEE-TGKRLFPVGRLDYDAEGALLFTDDGALAHKLTH--PSFQVPRTYLAKVKGAPDTATLDKLRGGVRLEDGMATPVSVS----------------------VFEAAERNTWLKIVVAEGRPHLIKRLCAAVGHPVV------------------------------------------------------------------------------------
>UniRef50_Q3MC44(92-233:288) Pseudouridine synthase n=21 Tax=Cyanobacteria RepID=Q3MC44_ANAVT   E=1e-12 s/c=0.54 id=24% cov=54%
-----------LLLNKPTGVVS--TCYDPQGRKTVLDLLPEELrkGSGLHPVGRLDAYSTGALILTNDGDLTFKLTH--PSHNIPKTYQILVKGHPPEAVLKMWREGVLLDGRKTRKAKVS-----------LLESLAEK-----------SRLEIVLQEGRNRQIRRVAEQLGYPVI------------------------------------------------------------------------------------
>UniRef50_A0Z1Z6(25-208:208) Pseudouridylate synthase n=2 Tax=Proteobacteria RepID=A0Z1Z6_9GAMM   E=2e-12 s/c=0.41 id=23% cov=57%
---------DIILLNKPFRVLSQFSDRDNDpPRLTLANLL---SAPEFRVAGRLDYDSEGLTLLTDDGKLQQQIAN--PKFKVWKTYWVQVEGAPKQQAIEQL---------TSGVVLNDGLTKPAK-----VRAIDPPDLWERSPSVRFrahipdAWLEISIQEGRNRQIRRMTAAVNLP--------------------------------------------------------------------------------------
>UniRef50_Q2NIZ3(62-210:245) Pseudouridine synthase n=5 Tax=Candidatus Phytoplasma RepID=Q2NIZ3_AYWBP  E=2e-12 s/c=0.50 id=21% cov=55%
-------------LNKPNGFLS--TAKDKKNRPTVLDLIEEASIQRLYPIGRLDFNTTGLLLITNDGDLTQKLTH--PSFCIPKEYHVKINACLQKKDLSTFCKGIIIDKKYLAVCK------------------EIDILKISYMPKPSTWLKLVITEGKNRQVRKMMQALGYQVL------------------------------------------------------------------------------------
>UniRef50_Q9Z8E0(87-164:232) Pseudouridine synthase n=1 Tax=Chlamydophila pneumoniae RepID=Q9Z8E0_CHLPN  E=5e-12 s/c=0.95 id=37% cov=30%
---ILWEDDYSIIYEKPPHL----------TTEQMAHM------TRFFTVHRLDKGTSGCLLMGKSKQAATELMKLFKQRKIHKQYIAFVFGHPKKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0IWI1(43-192:223) Pseudouridine synthase n=2 Tax=Comamonas testosteroni RepID=D0IWI1_COMTE  E=7e-12 s/c=0.49 id=27% cov=57%
----------LLCFHKPYGVLSQFTPEGK------WQGLKDWIDvPGVYVAGRLDADSEGLLLLTNDGQLQARIAD--PRHKMEKTYWVQVEGIPDEAALQ---------RLREGVELSDGKTLPAKARLiepQPLMWPRNPPIRVRQNIPDC-WIELIIREGRNRQVRRMTAAVGHP--------------------------------------------------------------------------------------
>UniRef50_C5WHE9(64-201:245) Pseudouridine synthase n=3 Tax=Lactobacillales RepID=C5WHE9_STRDG   E=1e-11 s/c=0.52 id=28% cov=31%
------------ILNKPAGFLS--ATKDRAQATVIDLLDETARQKDVFPVGRLDKDTRGLLLLTNNGQLAHDLLS--PKKHVTKEYLAKVAGIMTD--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A2S4Y2(46-195:235) Pseudouridine synthase n=7 Tax=Burkholderiales RepID=A2S4Y2_BURM9   E=4e-11 s/c=0.47 id=25% cov=58%
----------LIALNKPFGTICQFSA--HETRASLGDWVKT---PGVYPAGRLDADSEGLLLLTDDGALQAKIAE--PRHKLVKRYWAQVEGAPDAAALAALERGVDLGDYVSRPCRARFITPPGALWPR-------NPPIRHRAAIPTAWIELEIAEGKNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_A4J9G8(68-203:249) Pseudouridine synthase n=47 Tax=Bacteria RepID=A4J9G8_DESRM   E=1e-10 s/c=0.51 id=28% cov=52%
-----------LMLNKPQDVLS--ATEDASDKVVIDLLDPTYHSFNPFPVGRLDKDTEGLLLLTNNGKLAHQLLS--PKKHVPKTYYALVQGLVTEEDVAAFARGVELDDG-----------------YRTL-----PGQLKIIRSAPQSEIELTIYEGKYHQVKRMFEAVG----------------------------------------------------------------------------------------
>UniRef50_D1C7P2(63-200:337) Pseudouridine synthase n=1 Tax=Sphaerobacter thermophilus DSM 20745 RepID=D1C7P2_SPHTD  E=1e-10 s/c=0.50 id=30% cov=31%
-----------IMLNKPPGYIT--TVSDERGRRTVMDLVQ--VPERVVPAGRLDRPTAGLLLLTNDGDLLFRITH--PRYELEKEYEVLVDGHPPPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9HX48(11-159:189) Ribosomal large subunit pseudouridine synthase E n=30 Tax=Proteobacteria RepID=RLUE_PSEAE  E=2e-10 s/c=0.46 id=26% cov=57%
----------LLLFNKPFDVLTQF--NDEQGRSTLKDFI---PVPGVYPAGRLDRDSEGLLLLTNDGRLQARIAD--PRHKLPKTYWVQVEGTPDEEQL---------RRLREGVTLNDGPTLPA--EARLLDEptlWERVPPVRFRKSVPTHWLELVIREGRNRQVRRMTAAVGLP--------------------------------------------------------------------------------------
>UniRef50_B0RHF4(87-224:291) Pseudouridine synthase n=3 Tax=Actinobacteria (class) RepID=B0RHF4_CLAMS  E=3e-10 s/c=0.50 id=23% cov=53%
-----------LMLNKPVGIYS--SLRDERGRPDLREFTEEFEERLFN-VGRLDAETSGLLILTNDGDLAHVLAH--PSFGVLKTYIAKVTGRVTPQTIQRLTQGVDLEDGP----------------------IQADRARILSGGGDQTLVEITLHSGRNRIVRRMLDEVGHPV-------------------------------------------------------------------------------------
>UniRef50_C6VXU0(383-517:555) Pseudouridine synthase n=1 Tax=Dyadobacter fermentans DSM 18053 RepID=C6VXU0_DYAFD  E=3e-10 s/c=0.50 id=28% cov=28%
-----------ILINKPKDYIT--TTDDPEERKTVLDIIAGACSERVYPVGRLDRNTTGLLLLTNDGELAEKLTH--PSSGIKKIYQA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C2KV26(47-196:239) Pseudouridylate synthase n=1 Tax=Oribacterium sinus F0268 RepID=C2KV26_9FIRM  E=5e-10 s/c=0.45 id=27% cov=53%
--EIVYKDEpihyeefSYYMMNKPVGVLS---STEDRKQKTVLDLFSDKHRKDLFPVGRLDKDSEGLLLIMNDGALAHKLLS--PKMHIEKKYLVEIPGKISEEELDRL--------RQGIQYDTDLIAMPA--KARCLSSTEEG-----------SRVEVIIMEGKFHQI------------------------------------------------------------------------------------------------
>UniRef50_B6EJI1(68-210:354) Pseudouridine synthase n=8 Tax=Gammaproteobacteria RepID=B6EJI1_ALISL  E=5e-10 s/c=0.47 id=23% cov=29%
----------VLAYHKPEGELC--TRHDPEGRRTVFDRLPKIKDSRWVSVGRLDANTAGLLLFTTDGELANRLMH--PSRKVEREYMC----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3M7K0(3-152:262) Pseudouridine synthase n=13 Tax=Acinetobacter RepID=A3M7K0_ACIBT   E=6e-10 s/c=0.45 id=23% cov=56%
----------IVILNKPYDVLSQFRKDEAHMTVS-----DFVDDPTLRIAGRLDMDSEGLVFLTDHGGLNQFITN--PANKKYKTYLVQVDGDVTEEAL---------EQLRKGVELNDGMTLPA----KAIKVSEPEWLWDRDPPVRYrasiptSWIEISICEGRNRQVRRMTSAVGFP--------------------------------------------------------------------------------------
>UniRef50_C1XNC4(74-213:257) Pseudouridine synthase n=1 Tax=Meiothermus ruber DSM 1279 RepID=C1XNC4_MEIRU  E=6e-10 s/c=0.48 id=26% cov=54%
----VYQKFFYLLLNKPAGYIT--STKDPSGTPITALLPEEFWRNDWMPVGRLDKDTEGLLLLTTDGELLHRLTH--PRWKVTKRYYVELASPATPEDV-------------------------AVFAAGTLElEGEPLQPAELYLGPDPRKVELVLREGRFHQVKRMFAARG----------------------------------------------------------------------------------------
>UniRef50_A4CJ52(128-268:303) Pseudouridine synthase n=5 Tax=cellular organisms RepID=A4CJ52_9FLAO  E=6e-10 s/c=0.47 id=24% cov=53%
-----------VLLNKPRNFIT--TTRDEKGRRTVMELISRASNARLVPVGRLDRNTTGLLLFTNDGELAKKLTH--PKHGVRKIYHVELDKTFKSA---------DLGKLREGLELEDG-------RIEVDEASYIDGASKKE-------VGVELHSGRNRIVRRIFEHLGYQVV------------------------------------------------------------------------------------
>UniRef50_A4S9F7(105-253:287) Predicted protein n=3 Tax=cellular organisms RepID=A4S9F7_OSTLU   E=1e-09 s/c=0.44 id=22% cov=22%
------EDvDGLLIVmHKARGVVCSHDVREGTSVYDALPERWRRRKPSIESVGRLDKDTSGLLLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P0AA45(62-198:231) Ribosomal small subunit pseudouridine synthase A n=156 Tax=Gammaproteobacteria RepID=RSUA_ECO57  E=2e-09 s/c=0.48 id=21% cov=52%
-------------LNKPQGYVC---STDDPDHPTVLYFLDEPVAWKLHAAGRLDIDTTGLVLMTDDGQWSHRITS--PRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKD------------LTKPAVLEVITP------------TQVRLTISEGRYHQVKRMFAAVGNHVV------------------------------------------------------------------------------------
>UniRef50_Q12AB3(160-298:544) Pseudouridine synthase n=8 Tax=Proteobacteria RepID=Q12AB3_POLSJ   E=4e-09 s/c=0.46 id=29% cov=24%
----------VIAYHKPSGEVV--THDDPQNRPTVFRRLPKLFQGKWQSVGRLDLNTEGLLLLTSSGELANKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1IR68(74-207:254) Pseudouridine synthase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=Q1IR68_ACIBL  E=5e-09 s/c=0.48 id=26% cov=22%
------------VVNKPRGLIT--TASDEKGRETIYSLL-PPDSPWVAPVGRLDKASEGLLLLTNDSEWAAK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0MSS4(277-439:451) Pseudouridine synthase n=1 Tax=Alistipes putredinis DSM 17216 RepID=B0MSS4_9BACT  E=5e-09 s/c=0.39 id=24% cov=52%
-----------LVLNKPKGYVT--SLDDPHADKTVMELVKDACTERIYPVGRLDKNSVGLLLFTNDGDLTRQLTH--PSFQKKKIYQVSLDKPLTKADMEQIAQGI------------------------TLEDGEIYADEIAYVKEDKTEVGIEIHSGRNRIVRRIFEHLGY---------------------------------------------------------------------------------------
>UniRef50_Q4FV02(6-171:208) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=Q4FV02_PSYA2   E=5e-09 s/c=0.38 id=17% cov=60%
----------LILFNKPYGVQSQFrdDSNNDHTTLS-----EYFTDKSLRIAGRLDATSEGLLILTSDGRINKAITQppsaknfAQNKQKQGKTYLVQVEGVVTAVQLKELAsgvILKDGKTLPASATLLDEADLP-ITLWQR------DPPIRERKNIPTSWLMLTIYEGKNRQVRRMTAHVGLPCL------------------------------------------------------------------------------------
>UniRef50_Q2NZN4(99-243:286) Pseudouridine synthase n=13 Tax=Xanthomonadaceae RepID=Q2NZN4_XANOM   E=8e-09 s/c=0.44 id=20% cov=53%
-----------LMLNKPRGVVT--TVRDEQGRDTVYRCFDGAGLPWIAPVGRLDKASEGLLLFSNDPQWAATVTD--PATGPDKTYHV---------QIDCLPNVAQLAQLQAGVVDPDPEGEGMLLRAKQVSVLR--------EGERNAWLEIVLDEGRNRQIRRLLAA------------------------------------------------------------------------------------------
>UniRef50_A8IBT7(141-268:301) Pseudouridine synthase n=1 Tax=Chlamydomonas reinhardtii RepID=A8IBT7_CHLRE  E=9e-09 s/c=0.49 id=29% cov=45%
----------LVFINKPAGVRVHGraagdvdsaggrDGGGPTLDSVMGEALRFGEQDEPKLVHRLDAQASGVMVVARNADAAAWLSAAFRGK----------SRQPRQSGRIRFP------------VAVDGSFYPAVSSYRV-----------RGTGCGVTWVELTPETG-----------------------------------------------------------------------------------------------------
>UniRef50_A3HY40(262-348:434) Pseudouridine synthase n=1 Tax=Algoriphagus sp. PR1 RepID=A3HY40_9SPHI  E=1e-08 s/c=0.72 id=33% cov=28%
-----------VLLNKPKDFIT--TTDDPLERKTVMALVGNACEERIFPVGRLDRNTTGLLLFTNDGELAAKLSH--PSNQIKKIY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0L0G8(67-259:369) Pseudouridine synthase n=1 Tax=Halothiobacillus neapolitanus c2 RepID=D0L0G8_HALNC  E=1e-08 s/c=0.32 id=26% cov=71%
----------VIIYHKPEGEIT--STSDPEGRPTVFGSLPAIRQGRWITVGRLDFNTSGLLLATNDGELANRLMH--PSHQIERTYAVRVLGGLTEDQVKQLTTEVQLDDGP--------------------AHFDQLSDAGGTGVNR--WYHVTLREGRNREIRRMIEAVGAVV--------SRLIRISYAGIPLPP------RLK---PGRAQ------DLPPEMEDALVKLvGLR---PETRRK--------------
>UniRef50_Q4DAY9(171-492:665) Putative uncharacterized protein n=2 Tax=Trypanosoma cruzi RepID=Q4DAY9_TRYCR  E=1e-08 s/c=0.19 id=29% cov=64%
----------LLVIHKPAGVPTHAGGRYFMNSCTAMLeyvlapkRLRAWLLQRdpmlqsivstryltetecqellayymvkdegsmaeyvsierlPRPCYRLDKVTSGVLLLGVSQAATRRVGEALTRKTkqmeevflwklrliasddkkttrvggvhsieertlrefnvgVRKRYLARVHGYFPNDASHALHSCRvrkenagdgdhrttekvffitiptnptirrcdavkeealgvvgppvllasrlmqfkfrdgdtteePPARDQEGKQQREPFYQDAATFCQPLRYFT---SGSGQASEGESLVHCVPFSGRMHQIRMHLSDWGHPIIGD----------------------------------------------------------------------------------
>UniRef50_A0L6G3(133-270:332) Pseudouridine synthase n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L6G3_MAGSM  E=2e-08 s/c=0.45 id=15% cov=31%
-----------IILHKPKSIIC--TRSDPQGRRTIFDLIENHGSSRLITVGRLDINSEGLIILTSDGQLAHGLMH--PSREVPRVYRVKTHGIL----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5ELL5(85-222:268) Pseudouridine synthase n=3 Tax=Acidithiobacillus RepID=B5ELL5_ACIF5   E=2e-08 s/c=0.45 id=23% cov=23%
----------VLLLHKPRGVLT--TRQDERGRATVYDLL--PGSPWLAPVGRLDQASSGLLLFSNDPHWAQRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2QMI8(465-599:638) RNA-binding S4 domain protein n=16 Tax=Bacteroidetes RepID=D2QMI8_9SPHI  E=3e-08 s/c=0.46 id=33% cov=23%
-----------VLLNKPKDYIT--TTEDPEERKTVMELVADAGKFRMYPVGRLDRNTTGLLLITNDGELADKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1YVK2(59-197:235) Pseudouridine synthase n=3 Tax=Gammaproteobacteria RepID=Q1YVK2_9GAMM  E=3e-08 s/c=0.44 id=22% cov=21%
------ENRYFM-LNKPAGVVS---ATKDSNNSTALDLIFEHRSDELQIAGRLDIDTTGLLLI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8BNG7(148-425:568) DRAP deaminase n=2 Tax=Giardia intestinalis RepID=A8BNG7_GIALA   E=7e-08 s/c=0.22 id=22% cov=70%
------EGDHVF-CEKPASMPVHPCGKYCYHSvneLVASPDTKLTTKKSLRACNRIDKLVSGLIVMADSSKEAEQKRNEIVERGNVKVYLANCRMVstdisPRRVCLIWGPMGLRfkgnytsrcihfnthtelfganlerldkynecieqltacshsfGKGVTFMRDKEMLWFQDSDTYSRFVSSKKCTALlqdliavqldptqsmadigehqaaitvieyVHVDSSTQTALAMCVPITGRTHQLRLHLQAAGTPIHNDPSHGGLQAN-------------------------------------------------------------------------
>UniRef50_Q2NSN0(62-198:235) Pseudouridine synthase n=7 Tax=Gammaproteobacteria RepID=Q2NSN0_SODGM  E=2e-07 s/c=0.43 id=23% cov=50%
-------------LNKPQGYVC---STDDPDHPTILYFIDEPVPDKLHAAGRLDIDTTGLVLLTDDGQWSYRLTS--PRHHCEKDYLVTLEQPLAAEITAQFAAGI------------------------LLRGEKLPTRPARLATLSPLKVRLTISEGRYHQVKRMFAAVG----------------------------------------------------------------------------------------
>UniRef50_A8SLU4(42-196:230) Pseudouridine synthase n=1 Tax=Parvimonas micra ATCC 33270 RepID=A8SLU4_9FIRM  E=2e-07 s/c=0.38 id=22% cov=27%
-------------LNKPIGYSS--TAKAQFQEKIVLDLI--DSKERIYPVGRLDKDSFGLLLLTNDGDLAFRLTH--PSHNVEKEYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001745920(62-198:235) putative pseudouridylate synthase n=1 Tax=Verrucomicrobium spinosum DSM 4136 RepID=UPI0001745920  E=6e-07 s/c=0.42 id=29% cov=49%
-----------IMLHKPVGYLS--ATRDPQH-PTVIDLIDHPARETLHIAGRLDRSSSGLLLLTNDGRWSRRLTE--PGEKVDKVYLV-------ETAEPIAPEAVELFAKGFYFHTEDLTTLPA----------ELGILGER-------LARVTLHEGRYHQIKR----------------------------------------------------------------------------------------------
>UniRef50_A8FRI1(38-187:218) Pseudouridine synthase n=17 Tax=Bacteria RepID=A8FRI1_SHESH   E=7e-07 s/c=0.38 id=20% cov=57%
---------------KPYGYLSQFVPERRKSKKLLAELALFPAGT--MAIGRLDHDSEGLLLLTTDG----MVSHQVRSKKVEKEYYVQVDGDID-----DAAILKLQTGVEIGIKGEKYLTLPCK-VFKLENEPELPSNGRKPRDPKHgpmSWVSITIGEGKNRQIRKMTAAAGFP--------------------------------------------------------------------------------------
>UniRef50_A5ZYR1(73-206:315) Pseudouridine synthase n=2 Tax=Clostridiales RepID=A5ZYR1_9FIRM   E=1e-06 s/c=0.42 id=22% cov=52%
----------LLLFYKPRGIVCSTKKQRQETTVTEFL----DYPVRVYPVGRLDKDSEGLLLLTNQGDLVNRIMRAGNYH--EKEYEV-----------------TVDKKITETFIRKMSSGVP------ILGTVTRPCTVYKTGDKSFSII---LTQGLNRQIRRMCEYLGYHV-------------------------------------------------------------------------------------
>UniRef50_D2UX35(151-290:362) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2UX35_NAEGR   E=1e-06 s/c=0.40 id=25% cov=20%
----------LYAYHKPRGVLC-SRVDNGGNRETIYQRLERMGFGHLISVGRLDYNSEGLILL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI00017431E5(2-66:69) tRNA pseudouridine synthase A n=1 Tax=candidate division TM7 single-cell isolate TM7a RepID=UPI00017431E5  E=2e-06 s/c=0.85 id=19% cov=24%
---VIFENEDFFIVNKAEKIPMHKGTGHKYGLSEVFKKI--YKSENINFANRIDFETSGLVIGCKT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q30NZ7(61-199:228) Pseudouridine synthase n=3 Tax=Campylobacterales RepID=Q30NZ7_SULDN   E=3e-06 s/c=0.39 id=31% cov=21%
--------ERLVILmNKPHGVVCsHSDSGVLIYSLLPPRWQRR--NPKVSTIGRLDIDTTGAILL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0VQK2(73-205:248) Pseudouridine synthase n=2 Tax=Alcanivorax RepID=Q0VQK2_ALCBS   E=3e-06 s/c=0.41 id=21% cov=23%
-----------LMINKPAGVVS---ATRDEHHPTVLELLPRGQREGLHLAGRLDFNSTGLVLLTNDGAWSRRLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1K3P0(324-472:500) Pseudouridylate synthase n=3 Tax=Betaproteobacteria RepID=A1K3P0_AZOSB  E=3e-06 s/c=0.37 id=21% cov=53%
-----------ILLHKPVGYVSgQPEPGYEPAVTLiggdnqfdrdVAQRFHPSQLKGLAPAGRLDIDSTGLLVLTQDGRIARQLIG--DDSKVEKEYLVRVEGELVDDGLALLNHGLSLDD-------------------KPLRPAKVEWINEDQ-------LRFVLKEGRKRQIRRMCELVGLRVVG-----------------------------------------------------------------------------------
>UniRef50_A5IKF7(61-190:239) Pseudouridine synthase n=5 Tax=Thermotogaceae RepID=A5IKF7_THEP1   E=5e-06 s/c=0.42 id=23% cov=32%
-----------ILFHKPSGYVT--STKDPH-SETIMEFLPPLKG--IFPVGRLDKDAEGLLIITSDGDFAHRVIS--PKWSVEKEYIVKVEGEVTEDKI-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6WWG1(104-325:347) Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC 29098 RepID=B6WWG1_9DELT  E=8e-06 s/c=0.24 id=23% cov=64%
---------------KPAGWHSVSLAGGGGRSLEAAipsLWAEGAVPPAWALLQRLDARTSGIVCaaVAEDEDSLAATVRDFRQaeagGRCCKGYLALLSGSLEREACVRRALDMAQRRVVRVLDSEAADAAR-WTWFRPLyhWQGEACHAFARELCRRFSlsvpslpdsltLAGCTIHRGARHQIRAHAAALGHALWLDGLY-------------------------------------------------------------------------------
>UniRef50_Q7MMX9(67-196:347) Pseudouridine synthase n=43 Tax=Vibrionaceae RepID=Q7MMX9_VIBVY   E=8e-06 s/c=0.41 id=20% cov=50%
-----------IALNKPTGITCTTERNIPGNIVDFI-----GHKKRIFPIGRLDKPSDGLIFLTNDGDIVNKILRAGNHH--EKEYVVRVDKPITPEFI-----------------------KAMSSGVNILDTVTLPCKVTQETKFSF---RIVLTQGLNRQIRRMCEALGY---------------------------------------------------------------------------------------
>UniRef50_Q1J0B9(70-198:253) Pseudouridine synthase n=5 Tax=Deinococci RepID=Q1J0B9_DEIGD   E=1e-05 s/c=0.41 id=23% cov=50%
-------------LYKPAGYVT--TARDEYGRRNVLSAM--PPIPGLHPVGRLDKDSEGLLLLTTDGQLTLTLTHPRYGH--EKAYRAWTAGQPVAAELRVLETGIELADGPAR-------------------------ALSARPARGGALV--TLTEGRNRQVRRMLDAIGYPV-------------------------------------------------------------------------------------
>UniRef50_Q3IC94(65-197:327) Pseudouridine synthase n=6 Tax=Bacteria RepID=Q3IC94_PSEHT   E=1e-05 s/c=0.40 id=21% cov=51%
-----------IAYNKPVGITCTTERKIQSNIVKAV-----NYPDRIFPIGRLDRPSEGLIFLTNEGDIVNKILRAGNNH--EKEYVV----------TVDKPLNR-------QFVAKMGNGVP------ILDTITKKCKVTQTGAQQFTII---LTQGLNRQIRRMCEYLGYEVV------------------------------------------------------------------------------------
>UniRef50_A5GM98(2-121:171) Pseudouridine synthase n=3 Tax=Synechococcus RepID=A5GM98_SYNPW   E=0.0002 s/c=0.40 id=18% cov=45%
---------------------------------------------------RLDADSEGLLILTENGRLQQRLTDPRFGHW--RTYWVQVEGLADHGHLAALEQGVVIKGQRTRPARA-----TSLDSSFWFDLPERTPPIRERRTIPTSWLSISLREGRNRQIRRMTAAVGLP--------------------------------------------------------------------------------------
>UniRef50_B7G6C8(2-98:151) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G6C8_PHATR  E=0.0002 s/c=0.50 id=28% cov=38%
-----------------------------------------------HPVGRLDYDTSGLLLFSSSGALTQRLLH--PKHEVEKEYVAVVTGIVVED------------------------------ELRATLAAGVRGYLNVFDAQALSTVRLTVSEGKHRMVRRILANCGHPVV------------------------------------------------------------------------------------
>UniRef50_D0MUX7(106-260:293) Ribosomal large subunit pseudouridine synthase F, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0MUX7_PHYIN  E=0.0008 s/c=0.30 id=23% cov=29%
-----------LVLNKPLGYVSsqpelnkTPAVRLLTFENECQELSRVKPRQNVEPValwkmavcGRLDVNSTGLLLFTQDGTVAKKLLD--PKGGIEKEYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q47417(115-371:376) tRNA pseudouridine synthase C n=252 Tax=cellular organisms RepID=TRUC_PECCC  E=2e-69 s/c=1.03 id=71% cov=99%
MLEIIYQDEHLVAVNKPSGWLVHRSWLDRKEKVVVMQTVRDQIGQHVYTVHRLDRPTSGVLLLALSSEVARALSQQFESHQMQKTYHAVVRGYVLDDGVIDYALTEELDKIADKFTNPDKAPQPAVTHYRSLAQAEMPVAIGRYPTARYSLMELKPQTGRKHQLRRHMSHIHHPIIGDTAHGDLRHNRGMESHFSCGRLMLHASELQLNHPVSGQPLTLQARWDAPWQGVVTQFGWKGILPEFEGVEFPADSGQDSE---
>UniRef50_Q9JVB6(105-341:374) Ribosomal large subunit pseudouridine synthase D n=39 Tax=Proteobacteria RepID=RLUD_NEIMA  E=1e-62 s/c=1.02 id=28% cov=85%
-LDIVYEDDTVIVVNKPAGLVVHPAAGNWTGTLLNGLLAHCPElsqIPRAGIVHRLDKETSGLMVVAKTLPAQNSLVWQLQERTVKRIYRAVANGIVPFDGKIETQIGRDPHN-RLKMAVVKFGGKPAVTHVKVLERYLA-----------HSYIECSLETGRTHQIRVHMREANHPLAGDPVYGNPRHPCGDTVKEAVKslgaRQALHAYRLSFTHPESGETVSFEAPIPDDIYHLLS----------------------------
>UniRef50_C4FYR8(99-325:326) Pseudouridine synthase n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4FYR8_ABIDE  E=5e-62 s/c=1.06 id=31% cov=85%
-LDILYEDEDVILINKPKGMVVHPAAGHYTGTLVNALMYHCRdnlsginGELRPGIVHRIDMDTTGVIIACKNDVSHRIIAEQLKEHSIKRKYQAIVYGVFKDEEGRIEGSIGRSKTDRKKMAVI-PDGKPAVTHYRVIRNYTSPN------GNNFAHIECELETGRTHQIRVHMTSIGHPLLGDEIYGAAK------NPFKLDGQALHAEMLGFVHPRTGEYMEFHAPLPEYFSKLLTKL--------------------------
>UniRef50_A3EQJ0(95-329:339) Pseudouridine synthase n=1 Tax=Leptospirillum rubarum RepID=A3EQJ0_9BACT  E=4e-61 s/c=1.01 id=33% cov=83%
-LEILYEDEDLIVISKPPGLVVHPAPGHSSGTLVNGLLFHFQsqgdeqkkgepeeeeeaeRPLRAGLVHRLDQDTSGVMVVGKTESVVLDLMNQFKDRSVSKKYLALVKGIlPKKRGEINAPIGRSTHDRKKFTVRQD--GKPSVTRYRVLETYHE----------NYSLLEVTLLTGRTHQIRVHFRYLGFPLLGDAVYGSK-----GTENKNFPRQMLHAWKLSFQHPSSNSKMEFEAPLPPDFVSALERL--------------------------
>UniRef50_B2A2J2(91-319:328) Pseudouridine synthase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF RepID=B2A2J2_NATTJ  E=3e-60 s/c=1.02 id=27% cov=86%
-LDIVYEDEYLLVVNKPRNMVVHPGAGNYRDTMVNALLYHCQNlsdgtsYERPGIVHRLDKDTSGLLVVAKQNETHDILSEEIKNRRVARTYLALVIGDFsKKKATIDLPIGRDPRNRKKMAVVH--GGKRAITKVEMLRSFQNPE--------KISYLKCSLETGRTHQIRVHLSHLGYPLLGDPVY-RGKTGKNVDIDKNLTGQALHSFSLAFTHPVFKKTMVFRAPLPSDMMNLISKL--------------------------
>UniRef50_A6DUC9(90-320:323) Pseudouridine synthase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DUC9_9BACT  E=4e-60 s/c=1.01 id=30% cov=85%
-LDIIYEDDDILVVNKPAGMVVHPGAGNYTGTLVNALLGRdldtfsamDDGSSRPGIVHRLDKETSGVIIVAKSAKNLDKLSRSFARRDVEKYYVALCRGTIRVgRDTITSHIGRSRSNRQKMENTNDSNrGKEAISHYKVLA-----------DNNGATLVKLKIDTGRTHQIRVHMSGINHPVVGDKLYGVRRLD----EKESPDRHILHAWRTRIIHPGTQEIMTFTAPLHDDFKSVCDKFG-------------------------
>UniRef50_Q8XYX8(116-349:358) Ribosomal large subunit pseudouridine synthase D n=94 Tax=Proteobacteria RepID=RLUD_RALSO  E=7e-60 s/c=0.99 id=29% cov=87%
-LDVVYEDDTLLVINKPAGLVVHPAAGNWSGTVLNGLLHRYPQAaglPRAGIVHRLDKETSGLMVVARTLPAQTDLVRQLQARTVKRTYLALVWGETPEAGTIDAPIGRDPRDRTRMAIIETASGKPARTHFKTLDVVDLGRA-------QVSLVQCQLETGRTHQIRVHFESEGHPLLGDPVYTrNFRRGRPQTIKAPLPapfaRQALHAVRLGLVHPASGQSVHWHAGVPDDLAELMDAL--------------------------
>UniRef50_C8QZ10(96-318:324) Pseudouridine synthase n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8QZ10_9DELT  E=8e-60 s/c=1.04 id=33% cov=83%
----LYEDEDILVLVKPPGLVVHPADGHRQGTLVHGLLHHCRnlsgisGQLRPGIVHRLDKDTSGCLVVAKNDLAHHNLVQQFKGREVEKTYQALLRGILaEDTGQVVLPIGRHPVHRKKMAVR-REGGREAVTHWRVRQRF----------SAGYTLVELLLETGRTHQIRVHMAALGHPLAGDRLYG---RNPEKDMPYGIDRQWLHAWRLAFNHPRSGRRLTFTAPLWVDLQASLDRL--------------------------
>UniRef50_C4KBT4(1-268:648) Transaldolase n=2 Tax=Proteobacteria RepID=C4KBT4_THASP   E=2e-59 s/c=0.86 id=50% cov=96%
MLEILYRDDWLVAIHKPSGLLVHRSPIAAHEERFAVQLLRDQLGRRVYPAHRLDRGTSGVLLFALDREVARTLAQRFEAQAVDKRYLAVVRGHPPEHGVIEHALVRRLDAVEVRSGKgagardalpedvddsdspeaAEPVAQPARTRFRRLATVELPHAVDRYPSSRYALVELLPETGRRHQLRRHLKHIAHPIIGDATYGKGRHNRLFQALFGSHRLLLACTRLALAHPVTERPLEIVAPVAEDFAAVLAALGWQ----TAQRSTFEAES--------
>UniRef50_B9L028(88-321:322) Pseudouridine synthase n=2 Tax=Thermomicrobia (class) RepID=B9L028_THERP  E=2e-59 s/c=0.99 id=27% cov=83%
-IPVIYEDDDIIVFDKPPGIVTHPAPGHEHGTLVNALKairpdLQVQPSHRPGIVHRLDKDTSGLLVVAKTEAARLALLEQWQSRSVVKKYTALVHGVVePDSGTIDAPISRDPVERTKMAVV--SWGRPAITHFRVLERFRC-----------ATLLDVTIETGRTHQIRVHCAFIGHPVVGDSQYGGHRPFC-----VPVPRQFLHARYLRFVHPTTGQAIELETPLPYDLRTVLEAL--------------------------
>UniRef50_A6C0W7(93-335:342) Pseudouridine synthase n=1 Tax=Planctomyces maris DSM 8797 RepID=A6C0W7_9PLAN  E=6e-59 s/c=0.94 id=28% cov=86%
-IDIVYEDDWIAIINKPSDMIVHPGKGNYAGTLAGALQYHFDqlsdvaGQYRPGIVHRLDRNTSGIMVVAKDNQVHAKLSAQFEKRDVQKEYRAIVWGRMEFDTDYIDTFMCVHPRAREKMIVCDEGGnaRNAFTYYEVIERYQA-----------FTYVRLKPRTGRTHQLRVHMQHIGHSIVADRVYGGHKslkmkslgiqaeaDAAELESDVLIERQALHAYCLEFFHPQSGKPMKFEAPLPEDMQNTLAAL--------------------------
>UniRef50_A1URK8(80-329:336) Pseudouridine synthase n=2 Tax=Bartonella RepID=A1URK8_BARBK   E=6e-59 s/c=0.92 id=28% cov=88%
-LHILFEDDHIIVVNKPAGLVVHPGHGNWTGTLVNALIYHCGDSlsgiggvRRPGIVHRLDKNTSGVIVVAKNDLAHKGLSAQFSDHgrtgVLDRRYHALIWGSPnRNIGVITASLGRARYDRTKQAVIHSHNiyARHAVTHFSVIEKYQTCADKIPFA----SLLECRLETGRTHQIRVHMAHIGHPLVGDTVYGNAFKTKSNRFDstikeaiDLFNRQALHAASLTFEHPAKGNIMSFSAPLPQDMAELINHF--------------------------
>UniRef50_A6SXT6(115-340:342) Pseudouridine synthase n=1 Tax=Janthinobacterium sp. Marseille RepID=A6SXT6_JANMA  E=8e-59 s/c=1.01 id=25% cov=86%
-LAIVHEDAEMLVINKPAGLVVHPAAGNWSGTLLNGLLHYLPsisGVPRAGIVHRLDKDTSGLMVVAKTLIAHTDLVRQLQARTVKREYLALVWGTPNITGKIDASIGRHARDRIKMAVSENLTAKPAVTHFQRLAT-------GMLDGRPVSLMLCRLETGRTHQIRVHMQSIGFALVGDGLYGKQHLTTV------FPRQALHARRLGLIHPVSGEAVEWSSELPQDFAELIARAGIK-----------------------
>UniRef50_C8NEP8(80-300:308) Pseudouridine synthase n=1 Tax=Granulicatella adiacens ATCC 49175 RepID=C8NEP8_9LACT  E=1e-58 s/c=1.03 id=31% cov=82%
-LDIVFEDDSLIVVNKPSGMVVHPSKGHYSGTLVNALLYHSNSLSdstseeiyRPGLVHRIDKDTSGLLVIAKNNDVHQKLAEQIAENKMNREYIAIVDGHFAHeTGVVDAPLSRHQTNRLKR--VVEKGGKNAITHFEVLDSF-----------SDYSLVSCRLETGRTHQIRAHMEFIKHPIVNDPLYHPKGKNATEF------GQFLHARTLSFTHPLTGETLNFQVEPPKEFAEFIQ----------------------------
>UniRef50_Q3A0C2(83-316:326) Pseudouridine synthase n=13 Tax=Bacteria RepID=Q3A0C2_PELCD   E=2e-58 s/c=0.97 id=30% cov=86%
---ILYEDRHLIVIDKPPGMVVHPAPGHYQGTLVNALLHHCQdlsgigGELRPGIVHRLDKDTSGVMVATKTDSAHQSLAAQFKAHSITRRYIALIHGVLTGDRGSIDRPIGRHPTHRKKMSTTCRTGRHAVTHWRVLRRFD---------DDRLTLVELALETGRTHQIRVHFSEQQHPLLGDPVYGGSGRLKTINDPQLLKrakalgRQALHARLLGFQHPETGKYLEFSSPLPEDLRSVIDYL--------------------------
>UniRef50_Q30SZ1(1-236:241) Pseudouridine synthase n=2 Tax=Proteobacteria RepID=Q30SZ1_SULDN   E=2e-58 s/c=0.96 id=51% cov=91%
MLEILYQDEHLVAINKPSGLLVHRSPIDRHETEFAIQTLRNQLGRFVYPIHRLDKPTSGVLLFALDKESAKIMGEKFMAHEAKKSYIAVVRGYTLQSGEIDYALSIKFDKIADKDSSSDKEPQEALTHYKRLATVELDFEVGKYDKTRYSLVKLNPLTGRKHQLRRHMKHISHHILGDTKYGRGEHNKLIRQEFGCHRMLLHAIALEISHPYTKELLYIKAPLDVTFIEMFSFFGW------------------------
>UniRef50_A3M2Y1(115-350:350) Pseudouridine synthase n=18 Tax=Gammaproteobacteria RepID=A3M2Y1_ACIBT  E=3e-58 s/c=0.96 id=27% cov=84%
-LDIVYEDEDILVINKPVGMVVHPGAGNTSSTLVNALLYHSPKSAELsraGLVHRIDKDTSGLLVVAKNLEAQFSLSKQLGDKSVYRIYDLVTYGNIIAGGTIDEPIKRHPVDRVKMAIL--PGGRDAVTHYNVKERFR-----------DFTRVQAQLETGRTHQIRVHFSYIGHGLVGDQVYMNRVRIPAGASELlietlrGFKRQALHAAKLGLKHPRTGEEMLFEAPWPEDFTQLVN----------------------------
>UniRef50_Q1MQ60(83-305:541) Pseudouridylate synthases, 23S RNA-specific n=1 Tax=Lawsonia intracellularis PHE/MN1-00 RepID=Q1MQ60_LAWIP  E=3e-58 s/c=1.02 id=32% cov=82%
-LEILFSDEHLAIINKPPGLTVHPAPSCQESTLVHRLLkyfpkLIEQGGLRPGIVHRIDKDTSGLLCIALTEDTRLKLSKIFLDRKINKEYLALVHGVPSMEGYIAVPLGRDPKTKVK--VAVNPKGKPAHTEWRVLHRGKNDV---------YSILALTIQTGRTHQIRVHMKHIGHPLVGDKLYAGGHVNKT----FQCNRQMLHAWKLSFEHPITGKKMNFLCPPPKDFL--------------------------------
>UniRef50_A8GQ59(79-312:329) Pseudouridine synthase n=15 Tax=Rickettsia RepID=A8GQ59_RICAH   E=4e-58 s/c=0.97 id=28% cov=86%
-LDIIYEDDDLIVINKAAGMTVHPGAGHHDDTLVNALLYHTknlsdiGSAARPGIVHRLDKDTTGLMVVAKNNKAHMLLANQIEQRQVIRKYKALVWGVINPLAGVIKNNIGRSRVERQKMSILKYGGKEAVTHYKTLELFY---------GGTISMVECRLNTGRTHQIRVQLSHVKHSVVGDQTYGNNDRKiahsspALKAKLIDFKRQALHSWYLSFTHPTSNKIMEFSCELPRDMEAIIA----------------------------
>UniRef50_C0Q9S8(13-256:260) TruC n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0Q9S8_DESAH   E=7e-58 s/c=0.93 id=46% cov=94%
-LEILYQDEDLVAVNKPPGLLVHRTALATHETRFALQMVRDQTQGHVFPVHRLDRPTQGVLLFARNRNMATRMSHLFQTGKIQKTYLAVVRGHVKERGTIVHPLKNIKHPQDNKRINHSLKIDDAVTDYACLASVELPFYVDRYPTTRYCLVALIPKTGRRHQLRRHMKHISHPIVGDTVYGKSSHNRFFATHLNCTGLLLAARELCFVHPDTGIFITITAPLDKRFQEVISKFSWDEPTKELPR---------------
>UniRef50_P74346(98-327:327) Uncharacterized RNA pseudouridine synthase slr1629 n=19 Tax=Bacteria RepID=Y1629_SYNY3  E=2e-57 s/c=0.97 id=31% cov=83%
-LDILYEDEQLIIINKPAGLVVHPGPGHPDGTVVNALLAHCpdlagiGGVQRPGIVHRLDKDTTGAMVVAKTELALHNLQVQLKEKTARRLYWGIVYGSPKeIQGTVNLPVGRHPGDRQKMgIVPVEKGGREAVTHWRLLERI-----------GNHSWLEFQLETGRTHQIRVHSKQMGHPLVGDNLY-----TSPGSVNVNLPGQALHAHQLSLIHPVSGEIITAIAPMPAHFEKLL-----------------------------
>UniRef50_B5YKV0(82-311:315) Pseudouridine synthase n=1 Tax=Thermodesulfovibrio yellowstonii DSM 11347 RepID=B5YKV0_THEYD  E=2e-57 s/c=0.97 id=28% cov=82%
-IQVIYKDDYLIVLSKPAGMVVYPCAGHPDGTLMNALAYHvkklanVGAPFRPGIVHRLDKDTSGVMVVALDDETYYKLVEAFKKREIKKEYLALVYGQLRGSGKITTPVGRAIYD-RKKMSIKSKKAKEAITEWEVIKNFK-----------NYTFLKVKILTGRTHQIRVHFSSIGHPVIGDKTYGRKTYIEIGNKKIPVSRQMLHAHKIELIHPITEKLLQFEASLPDD----------------------------------
>UniRef50_A3HSB5(3-233:237) Pseudouridine synthase n=1 Tax=Algoriphagus sp. PR1 RepID=A3HSB5_9SPHI  E=2e-57 s/c=0.97 id=44% cov=89%
-LPILFEDDSIIAINKPAGLLVHRTSIAAQETVFALQILRDQIGMHVHPVHRLDRPTSGILLFAKKEEILPHLKNLFSERQIKKNYLTIVRGIPEQKKALIDHPLKSERSGRL---------QEAQTWYKVISETEIPfDTTGRYPTSRYSLLSVNPETGRTHQIRRHLAHIRHYIIGDKKHGDNKQNIFFQNQFGLENLLLHAIRLSFNHPITEETIEISCPVPEHFQSILKSLNLQEPL--------------------
>UniRef50_C8X1I9(91-336:547) Pseudouridine synthase, RluA family n=1 Tax=Desulfohalobium retbaense DSM 5692 RepID=C8X1I9_DESRD  E=2e-57 s/c=0.91 id=30% cov=92%
-VEVVYSDPDVVVVNKAAGVTVHPGTGCESGTLVhhlaaLYPELARFDGERPGVVHRLDKDTSGLLTVALNESARLALTRSFARREVDKEYLTLVHGRPEAEGTVDHPLGRDPQS-KIRMAVVPRGGKEALTRFKRVWT---------SPDGRVSLLRVRILTGRTHQIRVHMAYLGFPLVGDALYGPQAQAAFQRSRPLLARLakhhMLHAWRLAFPHPRSGRMVCCEQAMPKAM--------WRLVLGCGRRVQRVGLTGMPG----
>UniRef50_D0RPR1(81-320:325) Pseudouridine synthase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RPR1_9RICK  E=3e-57 s/c=0.93 id=28% cov=85%
-LNIIFEDQDIIIIDKPIGMVVHPGAGNYEDTMVNGLLYHCKnnlsgmnGEDRPGIVHRIDKDTSGLLVVAKNDQAHAFIAKQFEEHSIKRSYLVFVYGILRPLHGKIETLIGRNKTNRQKMSADVIRGKDAITNYETLEVFKGNKI------PDISLVKCILETGRTHQIRVHMSHKGNPILGDQTYGKKIKKIRGIDQefeeilKSLKRQALHAHTLGFIHPTTNEEVFFASELPDDL---------------------------------
>UniRef50_D1Y3Y9(116-336:345) Pseudouridine synthase n=1 Tax=Pyramidobacter piscolens W5455 RepID=D1Y3Y9_9BACT  E=5e-57 s/c=1.01 id=31% cov=82%
-FDVVYEDDDVIVVNKPAGVVVHPGAGRPDGTLVNGLMFRYpeigriGDSVRPGIVHRLDVGTSGLMVVARSDAAFRGLTEAFQAHEVLKEYLGLGVGALKaPEGTVDAPIGRDPRNRLKMCV--SWDGRDAVTDYKVLWTR-----------ARCNLIRVRLHTGRTHQIRVHMRALGCSLDGDTLYGPKDP----AQHILKDRVFLHSWRLGFRHPVSGERLEFRAPLPPELIAAL-----------------------------
>UniRef50_Q3AVX8(106-333:339) Pseudouridine synthase n=40 Tax=cellular organisms RepID=Q3AVX8_SYNS9  E=7e-57 s/c=0.97 id=29% cov=83%
-LDVLFEDEHIIVLNKSAGLTVHPAPGNKDGTLVNGLLHHCPDLPgisgklRPGIVHRLDKDTSGCIVVAKSQEALVKLQVQIQKRVASREYFAVVHGVPDgDSGTIIGAVGRHPVDRKKYAVVSDESGRYARTHWTLIERF-----------GDYSLLRFKLDTGRTHQIRVHCAHINHPVVGDPTYSRCRKLP-----LDLPGQALHAVQLGLDHPITGERMVFEAPLPPVMEKLL-----------------------------
>UniRef50_A1K5H7(1-256:260) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=A1K5H7_AZOSB   E=9e-57 s/c=0.87 id=46% cov=97%
MLEILYQDEHLVAIHKPSGLLVHRSALDAHEERFAVQLLRDQLGRHVHPVHRLDKGTSGVLVFALDRDTAGRLATQFETRAVRKQYVAIVRGHPAEAGTIDHPLSRRFDPVEHVAEDKVFAPQPAITRFRRLATAELPWAVDRYPTSRYALLALEPETGRRHQIRRHLKHISHPIIGDSTFGKGKHNRMFQAHFGSERMLLACTDIELRHPQRDAPLQLHAAPAPDFRAVADALGWHDALA---RLPADGDTGHN-----
>UniRef50_O50310(77-317:327) Uncharacterized RNA pseudouridine synthase Cpar_0723 n=13 Tax=Chlorobiaceae RepID=Y723_CHLP8  E=4e-56 s/c=0.91 id=29% cov=85%
-ITILYEDDDLMVIDKEAGMVVHPAFGNWTGTLANAILHHlgkdadelDKTEMRPGIVHRLDKDTSGLIIIAKNPTALHKLARQFANRQVEKVYKAIVWGVPKaESGTIKTNIGRSHKNRKVMANFPYEGaeGKHAITDYQVVE-----------DLGYFSLMDVTLHTGRTHQIRVHLQHLGHSILGDETYGGATPRTLPFSKsepftrnllELMSRQALHAQTLRFRQPTTGEPLSFSAPLPEDMELVLEK---------------------------
>UniRef50_A0LPH5(87-337:344) Pseudouridine synthase n=1 Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LPH5_SYNFM  E=6e-56 s/c=0.87 id=30% cov=92%
-LEILFEDDDVLVLNKAPGVIVHPGAGHEEGTLVHGLLAHcsrlasRGAPRRPGIVHRLDRGTSGALMVAKSERAYLELIRQFKHHEVGKEYLALVYGTMAGASGEIRTGMGRHPVDRKRMAVLEKGGREAVSQWKV-----------AVAWGEVSLLRVVIKTGRTHQIRVHLSHMQHPVVGDETYGGGKRKARAVKSDVLrellmevDRQMLHAVGLAFRHPVSGADLSFTAPLPPDFAGLLERIR---ISLQKEGAGRSDPSG-------
>UniRef50_A5WFS2(181-413:420) Pseudouridine synthase n=3 Tax=Psychrobacter RepID=A5WFS2_PSYWF   E=9e-56 s/c=0.94 id=29% cov=84%
-LDIIYEDDSVIVINKPVGMVVHPGAGNWSGTLVNGLLYHYPNQahlPRAGLVHRIDKNTSGLLVIGKTKAAQLELQEQLKDKSVYRHYQCVVAGDAPslaRQRTIDAPIGRHRTQRTKMTVT--STGKTAITHIMKI----------TPLSDTYSLLDVRLETGRTHQIRVHLSHIGHPIIGDDIYGNRQQLRAGLTPEqrqaiqSFPRQALHAYKLGFIHPETGESIELTAPLPQDIVEL------------------------------
>UniRef50_Q1J0S8(97-341:341) Pseudouridine synthase n=7 Tax=Deinococci RepID=Q1J0S8_DEIGD   E=1e-55 s/c=0.89 id=35% cov=87%
-LDVLYEDEHLIAVNKPPGMVTHPAPGVTSGTLVNALLGRLTLPEqpgavgpdgyRPGIVHRLDKDTSGVIVVAKTVEAHARLAAAFKDRSTHKTYLAIAAGMWKAQGpvSVNAPVGRHPT-ARQRMTVGGVGPREAQTLFTPLAT------HPDGHGRTLALVRAQPHTGRTHQIRVHLAHLGSPILGDAVYG--------RASAVMPRHALHAQFLTLPHPVTGETLHLHAPVPDDLLRAWVALG--GAVPA------------------
>UniRef50_C6JBH1(81-293:299) Pseudouridine synthase n=1 Tax=Ruminococcus sp. 5_1_39BFAA RepID=C6JBH1_9FIRM  E=3e-55 s/c=1.02 id=29% cov=81%
-LNIIYEDEDILVINKPADMPVHPSAGNYENTLANgiaWYFAEKGEDFVYRCINRLDRDTTGALILAKNPLSAAILSVQMKKRQILRTYLALVDGLLPDSGTINAPIARMEGSVITRE-VNFGTGESAITHYERLA-----------AGKEYSLAELHLETGRTHQIRVHMKYIGHPLPGDYLY--------NPDYRRINRQPLHSYQLEFTHPTTGKVMLFTAPLPIDFISAF-----------------------------
>UniRef50_Q6MEC0(87-312:318) Pseudouridine synthase n=1 Tax=Candidatus Protochlamydia amoebophila UWE25 RepID=Q6MEC0_PARUW  E=4e-55 s/c=0.96 id=27% cov=83%
-LSILYEDEHLLVINKPAGMVVHPAPGNWSGTFVNALLYYCQKLPllpdtiRPGIVHRLDKGTSGLLVAAKTLETQQKLIELFASRKVYKAYLAICIGRPA-DGEIQAPIGRHPIHRKQMAVI--PTGKPAISFCKTL-----------GWSDKLSFVQIEIATGRTHQIRVHMKYRGSPILGDPLYGQISLNQ----YYSVPHQLLHAAVLRFQHPISLENLEFCTPPPPEMVRLIKK---------------------------
>UniRef50_Q2SS88(95-316:322) Pseudouridine synthase n=4 Tax=Mollicutes RepID=Q2SS88_MYCCT   E=7e-55 s/c=0.97 id=28% cov=81%
-LNIIYQDDDLLVINKQNNITVHPSLNNTNNTIVNALLASDvelssiNGELRPGIVHRIDKQTTGLLIVAKNDKTHKLLSEMFKNHQIYKEYLAIVTGVIKPNKGLIDAPIGRSQTDRKKMSVTAKNSKHAITTFEVVERFLKN-----------TLIKCQIQTGRTHQIRVHFNYINHPVLNDPIYGKKHQ------EFTDFGQYLHAYKLKFTHPITKKEIELISPLPKEF---------------------------------
>UniRef50_B2RIT5(110-355:365) Pseudouridine synthase n=80 Tax=root RepID=B2RIT5_PORG3   E=1e-54 s/c=0.87 id=28% cov=86%
-LDIVYEDDVLLVINKPAGLVVHPGHGNYTGTLVNALAYYLREDPEydpmdpsLGLVHRIDKDTSGLLVVAKRAEAKSDLCKQFYYKTTHRSYRALVWGRFDYPiGTITGNIGRDLKDRLQMAVFPPDGdiGKPAVTHYQVLEELAY-----------VSWIECRLETGRTHQIRAHMKHIGHTLFADERYGGDQILRGNNTAnyrrfvqnclAICPRQALHAKTLGFRHPVTGVEMQFDSDIPADLTTLLER--WR-----------------------
>UniRef50_Q13E92(178-422:426) Pseudouridine synthase n=28 Tax=Alphaproteobacteria RepID=Q13E92_RHOPS  E=2e-54 s/c=0.87 id=30% cov=86%
-LEIVHEDDDIIVIDKPRGLVVHPAAGHETGTLVNALIAHCGESlsgiggvRRPGIVHRLDKDTTGLMVAAKNDRAHQSLSAQFADHgrtgELRRGYYAFVWGAPnRIRGTIDAPIDRHPHAREKMAVRD--GGREAITHWEVLETFT-----GRSGGEIVSLIACQLETGRTHQIRVHLAHIGHPLLGDDVYGPHFKTKasqlrpdARAALTDLGRQALHAYLLVLEHPSTGEVVAWESGLPADLKRL------------------------------
>UniRef50_A6VXE8(3-236:242) Pseudouridine synthase n=2 Tax=Marinomonas RepID=A6VXE8_MARMS   E=2e-54 s/c=0.91 id=44% cov=90%
-LDILFQDEHLVAVNKPAGLLVHRTNLAKDEEDAVVQRLRDQTGKWVFPVHRLDRGTSGVLVMAFSPEVARRLSTQFAESKTQKTYHCLVRGYCNESGVINYPLAKLNEQKGRSRFKIEGTEREAETGFTRLIQYQLPVPVSRYDSMRLSWLEVTPKQGRKHQIRRHFKHHLNPLVGDSCYGCRHINKVAKELWSEDfRLMLHASSLEFNHPITNQPITLKADLSDKIINILNKL--------------------------
>UniRef50_A9BZ16(51-310:319) Pseudouridine synthase n=9 Tax=Burkholderiales RepID=A9BZ16_DELAS   E=4e-54 s/c=0.82 id=49% cov=96%
-LHILWRDEHLVAVYKPAGWLVHRTGLDAHETRFVLQTLRDQLGCHVYPAHRLDKGTCGVLVMALHAQAAQRLGQAFAGQEVRKQYLALVRGWLPDAVEVDHALRPDD-------APEDAPAQPAQTSLRCLARLEWPEAfDPRHAATRISLVEALPATGRRHQIRRHLKHVAHPIIGDATHGKGPLNRWWAERLGLQRLWLHAHALELAHPMTGEPLRFEADWRqlghvadvQHWRALCALPGWQACagLPATARPDQTASAGAPG----
>UniRef50_C0QV86(109-324:329) Pseudouridine synthase n=2 Tax=Brachyspira RepID=C0QV86_BRAHW   E=1e-53 s/c=0.98 id=32% cov=81%
-LDILYEDKYLLVINKPAGMSVHCSPSEMSGTLVNALLYKikdfdfVGNKERAGIIHRLDKDTSGLMIIGKNANIVSSIQEQFKNRTIKKIYHAIVVGVLKdNYIEINLPIGRHHVYRKKMTVRED--GKEALTHIKVLKRF-----------NSHTLIEINLKTGRTHQIRVHSSYKGFPVAGDKIYSKSFSKYSG--------LMLVAKKIEFMHPITKELLDFEIDYPDYFTNFL-----------------------------
>UniRef50_C1A885(83-308:329) Pseudouridine synthase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A885_GEMAT  E=2e-53 s/c=0.93 id=27% cov=85%
-LDVVYEDEHLLVVDKAAGMVVHPAPGNWTGTLVNALLGRgeplaeGGGEDRAGLVHRLDKDTSGLLVVAKSDAAHRTLSSALAARQVTRRYAAVCWGHLaEERITVEKPIARDPRDRTRMAIVQS--GKASRTDFTRLARFDSVD-----------LLRAHLHTGRTHQIRVHLASTGHPVVGDDTY--GGGGGRRLALLPPRRHFLHAAWLRFRHPISGDLIDLRSPLPADLRTSLAALG-------------------------
>UniRef50_Q126H9(126-365:378) Pseudouridine synthase n=1 Tax=Polaromonas sp. JS666 RepID=Q126H9_POLSJ  E=3e-53 s/c=0.88 id=34% cov=88%
-FPVLFEDDFLLAIDKPAGVAVHGGSGVSFGVIEQLRMARPQADF-LELVHRLDRETSGILLIAKRRMALKLLQEQFRERETDKVYLALVSGnWPANHRVIDKALHKyllpggagEGERRVKVVPNDHPDGMRSVTLVKVKSAF---AALPAAPGTPFTLLEVTIKTGRTHQIRVHLANEGHPIAGDDKYGDFELNKSLQKSVaggaPLKRMFLHAWSLKFNHPKTRKTIHLETPLPDELQQFLS----------------------------
>UniRef50_Q28US1(94-339:354) Pseudouridine synthase n=43 Tax=Rhodobacterales RepID=Q28US1_JANSC   E=6e-53 s/c=0.85 id=31% cov=86%
---VIYRDDHIIAINKPAGLPTQGGTGQSRHVDGLAEALKFGLEDKPRLVHRLDKDTSGVLLMARTRMGAKALTDAFRLRSTRKIYWAAVAGsPLPRMGTIKLGLVKAPGHGRggenekMRAVPVDEiaqvdGAKRAETDYAVMSNL----------GGRVCWCALVPITGRTHQLRAHMAEIGHPIIGDGKYGGSGQENLGDgwgaqlGGEISRKLHLHARSLSFRHPMTGAQVNLVAPLPEHMAKTWDTLGW------------------------
>UniRef50_D1U4S9(99-350:596) Pseudouridine synthase, RluA family n=1 Tax=Desulfovibrio aespoeensis Aspo-2 RepID=D1U4S9_9DELT  E=7e-53 s/c=0.83 id=29% cov=87%
-LEVVFEDAHVAVIDKRAGLTTHPAPGEPGPTLVNHLLHRWPdvasdisgmDRQRPGIVHRLDKDTSGLMVVALTEGDRLRLAADFAGRRVRKVYLAVVLGRPAQPAGTIDAPMGRHPSQKTRMAVVARGGREAVSDYRVLWT---------GPRGLASLVAVRIHTGRTHQIRVHMAHIGHPLLGDSAYGPREnvewSRRPDRLAGLAPRQMLHAFHLSFRHPATCERVTLWRRPPADFCTLLAAL--------------------------
>UniRef50_B8FTI5(83-298:302) Pseudouridine synthase n=2 Tax=Desulfitobacterium hafniense RepID=B8FTI5_DESHD  E=1e-52 s/c=0.96 id=33% cov=82%
-LEILYEDDYFIAINKPAGQVVHPTPRYPRGTIgnaVVGYWLAKGEARPFRPIHRIDRNTSGVVVIGKNQFAHQQMAWQHAHGRIHKCYRGIVEGqVMEDQGTIKAPIALAPDSFIQRQI--SPEGSPAVTLYKVLERYQ-----------DASLLEFILETGRTHQIRVHCQHLGHPLLGDDLYGGNLA--------RINRQALHSSIYEFNHPLTGELTTIQAPLPEDLQRLLREL--------------------------
>UniRef50_A8RHQ2(69-283:287) Pseudouridine synthase n=2 Tax=Clostridium RepID=A8RHQ2_9CLOT   E=2e-52 s/c=0.97 id=30% cov=82%
-LSIVYEDEDILVINKDAGVPIHPSQGHYDNTLANAvswYFHEKGEAFTYRVINRLDRDTTGLLVLARHMLSACILSEQMTGRRIRREYRAIVLGHTPEEGTVDSPIARAEGSTIERR-VDHETGERAVTHFRTLLYNE---------EKDLSLVSLSLETGRTHQIRVHMRSIGHPLPGDFLYCP--------DYRYIDRQPLHSYLLRFEHPITGKEMEFTAGLPEDMKQLL-----------------------------
>UniRef50_B4U613(79-306:308) Pseudouridine synthase, RluA family n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U613_HYDS0  E=3e-52 s/c=0.91 id=27% cov=85%
-IDILYEDNDLAVVVKPSGMPSHTGPGHDENTLVNALLAKFgdlsviGGVERPGIVHRLDRYTHGLMVIAKNDVSHQKLSLMFKNKEVDKHYKAIVYGISRFKEQTIETFIRRHPTNRLKFEVANE-GKLAITKY-----------SLEKPLKNASLLDIKIYTGRTHQIRVHMSYIGHPIVGDTLYGYKHsYFDKTLEHMIGKRFLLVAYKLSFLHPKSQKPMEFEIDMPDYFKNVLKYL--------------------------
>UniRef50_C6VVP1(4-228:228) Pseudouridine synthase n=4 Tax=Bacteroidetes RepID=C6VVP1_DYAFD   E=9e-52 s/c=0.91 id=49% cov=81%
-LEILYRSDDLVAINKPNGLLVHRSPIASDADVFAVQLLRDQLSQKVYPAHRLDRKTSGVLLFALNENVNSEMQGKFMEGEITKTYHAIVRGHTADRGEIDYPLKRD-----------DGVTQDAVTHFETLARAEVPFALGKHATSRYSLVQLNPLTGRMHQLRKHMAHIMHPIIGDRPHGCNKQNRFFKEELGMIQMMLHAVSVEFVHPVSGQHVTIVAP--------------------------------------
>UniRef50_B7GLK3(80-292:292) Pseudouridine synthase n=11 Tax=Bacillaceae RepID=B7GLK3_ANOFW   E=1e-51 s/c=0.96 id=32% cov=81%
-LAIVYEDDYVIVINKPPHMSTIPSREHPHGTLANALLHHYeqqQLQTTVHVVTRLDRDTSGLVLVAKHRHVHHLLSEQQKQGRVKRRYEAVCHGYVIQlVGTIDAPIGRKGDSIIEREVRLD--GQRAVTHYEVLQQ-----------KNEMTHVSIQLETGRTHQIRVHFSHIGHPLVGDDLYGGLREH--------IDRQALHSCELTFFHPFFEKTMTFHAPLPDDIARLL-----------------------------
>UniRef50_C0N6T7(96-317:318) Pseudouridine synthase n=1 Tax=Methylophaga thiooxidans DMS010 RepID=C0N6T7_9GAMM  E=2e-51 s/c=0.92 id=31% cov=85%
--DIIFEDDSMLVLNKPSGLAVHAGSQIQVGVIEAFRIIKPELAF-LELVHRLDRDTSGCLLLAKSRDSLLNLQQQMLSDQIDKRYLTLLKGILPNAEElVEQPLLKNTVSSGERMVKVTPDGKRAKTLF-----------IRQQDLSLAQLTEVKLYTGRTHQIRVHAAWTQHPVAGDDKYGDREFNKTL-KSFGLKRLFLHAWRLGIRHPVSGEPMQLEAPLPTALQQVITKL--------------------------
>UniRef50_Q0VQN9(98-313:317) Pseudouridine synthase n=2 Tax=Alcanivorax RepID=Q0VQN9_ALCBS   E=3e-51 s/c=0.94 id=34% cov=83%
----VYEDDQLFVFNKPAGLAVHGGSGVSLGLIEALR-VMFPQERELELVHRLDRDTSGLIMVARRRSFLRKLQRLMQGGQIEKRYWLLCQGFKGKERTLDAPLLKMMNGN-ERIVRVSREGKPSVTHFRLLERF-----------AQAQLVEATLETGRTHQIRVHSQFGGFALLGDSKYGIAKGEALLAE-IGRRRLCLHARTLVFVHPNTGKRLTVTAPLDDDYEAILTAL--------------------------
>UniRef50_UPI0001C37137(92-318:338) ribosomal large subunit pseudouridine synthase D n=1 Tax=Chlamydia muridarum Nigg RepID=UPI0001C37137  E=3e-51 s/c=0.89 id=29% cov=83%
-LDKVYEDNMILVINKPRNMVVHPAPGHVQGTVVHALLHEigerlkqefPEEPWRPGIVHRLDKDTSGLLITVKTRRAKAVYSELFSSKQMKKMYIAICINSPAQKHIH-TRIARHPVKRKEMTVlsKDTEGGKEAITHCHVLAS-----------NGRLSVVALYPETGRTHQLRVHMKHLGTPILGDPVYGVPSIN----FRYGLDKQQLHAYSLVFTHPESAERVELVTKLPDDMTSLIEK---------------------------
>UniRef50_C1ZB48(82-323:325) Pseudouridine synthase, RluA family n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZB48_PLALI  E=1e-50 s/c=0.83 id=34% cov=86%
-LEILFEDDSLLVINKPAGLIAHPTGEIPDGTLINAVQHYldkqstHPGLERPGIVHRLDRDTSGAMAICKEHLSHRLLSIQFQLGRISKSYLALVEGVLTDDQlVIDLPIGRAPGcSSALMSCRADAlEAQASKTSLRVVERF-----------PQHTLVEAKPRTGRMHQIRIHLATIGFPIVGDEFYLKGGEIRPLvwpeservQVSLLINRQALHAACLSFAHPLTNEWQDFQAPLPDDLRQAieLARLG-------------------------
>UniRef50_Q3ECD0(148-430:430) RNA pseudourine synthase 2, chloroplastic n=4 Tax=Magnoliophyta RepID=PUS2_ARATH  E=1e-50 s/c=0.71 id=27% cov=85%
-LDIVYEDKHVLVVNKPAHMVVHPAPGNPTGTLVNGILHHCSLPcvdysnseedddsdeetfsddeemttspssyaasVRPGIVHRLDKGTTGLLVVAKDEHSHAHLAEQFKLHTIERVYVSLTTGVPsPPQGRIEIPIGRDSSNRIRMAAipggVRGGRARHAASRYKVIETF---------AGGGSALVEWRLETGRTHQIRAHAKYMGVPLLGDEVYGGtksmalsllqKRVSRSDQEEIielisRMDRPCLHAIVLGFTHPCTGEIVKFSCPPPSDLAE-------------------------------
>UniRef50_D1AV01(78-295:297) Pseudouridine synthase n=2 Tax=Bacteria RepID=D1AV01_STRM9   E=6e-50 s/c=0.92 id=28% cov=80%
----VYEDKYLAIINKYAGMVVHPSKGHEEDTLVNAIMYKIKdlsginGDLRPGIVHRLDKNTSGLIIIAKDDKTHFKLSEMFKNKEIKKIYYAIVKGKVnKKSGRIETMIGRNPNDRKKMAVVD--NGKLAITNFEVIDSNE-----------KFSLLKVDLETGRTHQIRVHLSHFFFPILGDSVYGRKDE---------YDRQMLHAYMLNFIHPITLEKIDVIGNFHSDFLRALS----------------------------
>UniRef50_D2ELJ1(78-296:301) Pseudouridine synthase n=1 Tax=Pediococcus acidilactici 7_4 RepID=D2ELJ1_PEDAC  E=1e-49 s/c=0.90 id=27% cov=83%
-IDVIYEDQDYLVVNKPPFLPTVQSARNQTDTLVnrvkNYYAERDYESQVVHVVTRLDQDTSGLVLFAKRRFAHTIMDQDLRQHRVQKYYLAMATGRFAQsHGLIDAPIERDPASFIKRRVASAGNGKPSKTEYWVLEQTDTD-----------SLLKVQLHTGRTHQIRVHFSELHHPLIGDPLYNETSF-------RSLQRQALHCFSLKFENVFRGKKIDVQAPIPNDMLEYWKK---------------------------
>UniRef50_C2W5F3(85-302:307) Pseudouridine synthase n=4 Tax=Bacillus RepID=C2W5F3_BACCE   E=2e-49 s/c=0.91 id=27% cov=83%
-LEVIFEDDHVLIVNKPAHMDTHPSNKGGTGTlanLVAFHLQMQGVETKVRHIHRLDKDTTGGVVFAKHGIAGVIMDRLLMERNIKRTYLALVEGKVrKKQGIIDEAIGRDRHHATRR--RVSQKGDRAVTHYKIEKYFK---------KQDVTLVTLQLETGRTHQIRVHMSHSGHPLIGDVLYGGQATY--------MPYQALHAMRIHFLHPITKEEITVEAPLPNNLNNIIESF--------------------------
>UniRef50_A8MF48(89-302:305) Pseudouridine synthase n=12 Tax=Clostridiaceae RepID=A8MF48_ALKOO   E=9e-49 s/c=0.91 id=27% cov=81%
----VYEDVDLILVNKEPGIVTHPTKSHPDWTIANgaaLYLKSKGIDCKVRFVNRLDMDTSGLLIIAKNAYAHHVLSEQMQEDRIEKKYIAFVWGVIKeDEGRIEAPIYRTTMDSIKR--VVDERGQESITEFKVLERYK-----------NATMVEVKLLTGRTHQIRVHMEHLGHPLIGDTLYGKE-------DAELIDRQALHAEYLRFWQPRFKRAIEVKADLPADLLSLRDKL--------------------------
>UniRef50_A5VJ18(78-295:301) Pseudouridine synthase, RluA family n=13 Tax=Lactobacillus RepID=A5VJ18_LACRD  E=1e-48 s/c=0.89 id=29% cov=80%
-IDIIYEDQDFLIMNKPAGVATVPAHNVPvADSLVNrvkgYYKRQNYENQVTHVATRLDRDTSGLVVFPKHRFAHAVLDEQLKKHLVKKNYLALIKGKVPaEHGYIDAPIQRDPNSFVKRMV--GKEGKASVTEYW-----------RQECNVQASLIKIRLHTGRTHQIRVHFASLGFPLIGDKMYGE--------ESGLIARQALHCYWLSFYSPFKGKNITVSAPLPSDFKNA------------------------------
>UniRef50_C9KQC1(77-287:302) Pseudouridine synthase n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KQC1_9FIRM  E=1e-48 s/c=0.92 id=29% cov=80%
-LDILYEDETFLVVNKPADMIVHPTHRAARDTLVHAvagYFERRGEAAGIHPLYRLDRDTTGIVILAKSARIQHAMTK--HHGQIYREYLALAQGHLDClSGRIDMPIGRDITRANHWQVRAD--GRRALTEYETIASWPA-----------YSLLKIHLLTGRTHQIRVHFAALGHPLLGDTAYDGSCDT--------IPRQALHAWRVHFFHPDTGKEIRIEAPIPEDMCRLI-----------------------------
>UniRef50_C4GBK1(103-339:341) Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles DSM 14600 RepID=C4GBK1_9FIRM  E=2e-48 s/c=0.82 id=26% cov=82%
-LNIIYEDEDILLIDKPAGMPSHPSMNHQKDTLanaVLYYYQKQGIPFVFRIANRLDMDTSGLVAVSKNSLAAARVKQMIDKRQIHREYLCIVEGSFSADsslakrdfvkmrydadgqmigGRIWAPISRREGSVLERRVNAS-DGQTALTDFEIVQE-----------GAKYSLLRVWLGTGRTHQIRVHMNYLGHPLPADYLYHPVYQD--------ISRQPLHSAKLRFPHPVSGRQMCFESRLPADMRHLLDNF--------------------------
>UniRef50_A2U235(3-233:234) Pseudouridine synthase n=3 Tax=Flavobacteriaceae RepID=A2U235_9FLAO   E=3e-48 s/c=0.84 id=36% cov=88%
-LEIIYEDAYLLCVTKPNNVLVHHAyhSRNMADEKSLLQLVSEETGLKVYPIHRLDRKTSGAILLAKEKEYVAKFQDLFTKNQIQKIYYGVVRGFSPSTKRIDSPVKGRDANV----------HKEALTELKTLAKITLDIAVKPYDSSRYSLIELFPKTGRMHQLRVHSNKISHPLIGDAKYGDKNHDMMFEQNFGFKNLFLHAGKLEFIHPYTQETLILKSTFPTDWIQLFEKFNWKNPL--------------------
>UniRef50_Q21K97(98-310:321) Pseudouridine synthase n=10 Tax=Gammaproteobacteria RepID=Q21K97_SACD2  E=3e-48 s/c=0.91 id=31% cov=81%
-----------LVVNKPAGLAVHGGSGVTLGLIEALRQAFPQYS-YLELVHRLDRDTSGCILVAKKRSMLRYLQELFRgEKRIHKRYLALVIGrWPSRRNLVDAPLLRKELQSGERIVRVSLDGKPSKTEFNVVQRF----------GESATLVEARPITGRTHQIRVHAQHQGHPLVGDPKYGNEVFD-LSVKKLGVNRLFLHAAGLSFKN-ADGEQVNIEVPLPAELQSVVAAF--------------------------
>UniRef50_D2RJC8(77-287:294) Pseudouridine synthase, RluA family n=2 Tax=Veillonellaceae RepID=D2RJC8_ACIFE  E=3e-48 s/c=0.91 id=32% cov=80%
-LSLLYEDEDLLVVDKPAGMLIHPTWSGARDTLVQAvggYFRRTGQHCGIHPLYRLDRDTTGVLMVAKSAFAKHALTR--DHSQIYREYLAVCEGRWgIPQGRIEHPIGRVAEGVDRWTVRPD--GRPAVTEYRILEE-----------NQEWTVLKIHLLTGRTHQIRVHFAHEGHPLVGDPLYGTKDG--------RIARQALHAWTVRFRHPRTGEEILLTAPMPGDMEGLL-----------------------------
>UniRef50_B8GX34(93-323:331) Pseudouridine synthase n=7 Tax=Caulobacteraceae RepID=B8GX34_CAUCN   E=6e-48 s/c=0.84 id=33% cov=84%
---VLYEDEEVLALNKPAGLAVQGGTKTTKHIDKLLSAWGEGVD-RPRLVHRLDRDTSGVLLLGKTPSAAARLSGAFAKRKAQKTYWAIVAGNPhPTEGVMELHLAKRGVGDRELVVpaqPKDPDAQPAETEFVTISR----------AGPRVTWMALRPHTGRTHQLRAHMKAMGHPILGDPKYGDEKSAPLSEGLK----LQLHARSILLPHPSAG-MLHIEAPLSPEMKEGFRKFGF------------------------
>UniRef50_P75485(80-299:309) Uncharacterized RNA pseudouridine synthase MG209 homolog n=2 Tax=Mycoplasma RepID=Y292_MYCPN  E=9e-48 s/c=0.87 id=29% cov=84%
-LDILYEDEQIMVVNKPNGLISHPTSFNESESLLGAALFHCN-HQPVFLVHRLDRDTSGVIMLAKNQSSLLHLQKQLQQRVMKRYYLALVHFPLDSlSGTISAPLERVGNNkVMWKVGNSSNKAKNAFTKFTVL-----------NQNEKAALIKCELLTGRTHQIRVHLQFIKHPVYNDPLYGLKSEQATEY------GQYLHAQQISFIHPTLNKEMGFEAQLDKTFSDKLDNLNLK-----------------------
>UniRef50_C1ZMP6(5-244:246) Pseudouridine synthase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZMP6_PLALI  E=1e-47 s/c=0.80 id=31% cov=90%
--HILFEDNHCLVVEKPAGVLTMGDETGDENMVQLAmddlkIRHQKPGNVYVGLVHRLDRPVSGVLLLAKTSKAASRLSAQFREREPEKVYLAIVEGqlNPAAGEIVDWLIKDQERNHTRVTSPQTPGAKQAKLRYRQLETLVTPEGIR-------TLVEVQPMTGRSHQIRVQLAHAGASILGDLRYGSKTPLGKM--------IALHARSLTFEHPVQKQPLTIYAPLPSDWKPFMNPLLWEKFQTAGESAAESS----------
>UniRef50_B1H0R5(88-293:296) Pseudouridine synthase n=1 Tax=uncultured Termite group 1 bacterium phylotype Rs-D17 RepID=B1H0R5_UNCTG  E=2e-47 s/c=0.93 id=26% cov=80%
-----------VVVNKRSGIVVHPSYGHLSGTLLNALMGYSAGKYNPYLIHRLDKDTSGVIVFAKTEKAKISISKQLQKRVVKKIYYAAVKGVIAENRGIIKAPLGRSPKNRKLVSVNPLAKKVAITEFKVIERKD-----------DYTLLKVRIITGRTHQIRSHMKYINHPVIGDKQYGG----PGTIGLKRCERQMLHAHNITFTHPSTSKTVKFIAQLPNDMKAIFK----------------------------
>UniRef50_C9RKF9(143-369:386) Pseudouridine synthase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RKF9_FIBSS  E=2e-47 s/c=0.84 id=32% cov=85%
-LDLVVQTEDYVIVNKPSGLASQPGSGTRPGESLVEYLwewgRNEGLDFKPTIAHRLDQETSGLIIAALHGDTLRDFTRMIREHVVDKFYFALVKGNLkKDRGTISESLLRTDSAKGSKMLVgqDDENAQKAITHYRVKQHYE-----------GYDLVKIKLETGRMHQIRAHFASIGHPLLGDTRYGDFALNREVKKLFGLNRLFLHSCRLEFD--WQGEHKVFDCPLPKELRDVIKQL--------------------------
>UniRef50_C6VRD0(78-292:300) Pseudouridylate synthase n=4 Tax=Lactobacillus RepID=C6VRD0_LACPJ   E=2e-47 s/c=0.89 id=31% cov=80%
-IDILYEDRDYLIVNKPAGVASVPAHALPDNTLANrvkgYYQAAHYDNEVVHITTRLDRDTSGIVLFAKHHFAHSIIDHQLKAHAMRKMYLAVVSGELtTDHGWLDAPIGRAADSFIKRTTRPD--GKPSLTEYWVVKRL-----------CNMTVVRVRLHTGRTHQIRVHFAASGHPLIGDALYGGPR-------DPWIQRQALHCMRLEFDDPFISQTLTTFAPLPADL---------------------------------
>UniRef50_A1ALH6(82-304:306) Pseudouridine synthase, RluA family n=9 Tax=Desulfuromonadales RepID=A1ALH6_PELPD  E=3e-47 s/c=0.85 id=32% cov=85%
----LHEDDDLIALNKPAGVNTQRTPYQLKGTLEYWaseYFRRQGNPEPARVIHRLDRGTSGVMLFPKHKRAAAWLSKRFHDGQVEKRYLALVSGTP---GQIEWRVDGPIGKIASARYGIVAGGRSALTEFRLLAE-----------SCGYALVEAKPLTGRTHQIRVHLQSCGLPIVGDGTYGGE----------PAARMMLHCASLRFAD-GGGREIVVEAPLDRDFRGLM----------EERGVAMTAPGLLNGTV--
>UniRef50_C3RIE2(81-294:294) Pseudouridine synthase n=4 Tax=Bacteria RepID=C3RIE2_9MOLU   E=3e-47 s/c=0.89 id=27% cov=82%
-LDIIYEDRELIVINKPAGLLSMAGGNEKEKTAYHLvgeYLKSKNKNARVFIVHRLDKETSGVLLFAKNEIIKNKLQNNWNDIVYKRGYLAIIEGKLKKKHGTIKNHL-DESKTQMVYIANNGKGKLAITNYKVLKESRYN-----------SLIEVFLETGRKNQIRVHMQSLGHSIVGDKKYG--------ATTNPIKRMGLHSHVFAFVHPDTKARMEFKAVVPEEFKKMFK----------------------------
>UniRef50_A6CF60(83-310:317) Pseudouridine synthase n=1 Tax=Planctomyces maris DSM 8797 RepID=A6CF60_9PLAN  E=8e-47 s/c=0.83 id=31% cov=85%
-LEVLYEDAWLIIVNKPPGMIAHPAGNILSGTVANALQYYLDQQTgvrsllRPGIVHRLDQFTSGILIVAKEHLGHRSLSIQFQQNRVSKSYLAIVRDQPKQDlFENNDAIGEHPTQAGVCMTTHPEAlrAKAAFTRFEVVERL-----------PGHSLIRAFPKTGRLHQIRVHLADLGFPIIADDFYGNDA--RLLDDRELISRQALHAEQIEFSHPVTSLRMNISAGVPADFQLALQR---------------------------
>UniRef50_Q30SG9(78-299:323) Pseudouridine synthase n=5 Tax=Epsilonproteobacteria RepID=Q30SG9_SULDN  E=2e-46 s/c=0.85 id=24% cov=83%
-VEILYEDDDILVINKPTGLTVHPAPSVKEATLVDWLKHKgmrlssLSGEERHGIVHRLDKGTSGAMVIAKNNSTHEFLSDQLQDKSMGRYYLAVINPPLKDELTEVIFPIARSSHNRLKMA-PLEHGKYAKSAFKVLAYSNDEANQ---------LIACKLYTGRTHQIRVHLESLNRHIVGDHIYAQSPKQEKSE------RILLHAYIIYFIHPKSKERVSFVASLDKGMQEYIDK---------------------------
>UniRef50_A4VJG2(39-243:244) Pseudouridine synthase n=18 Tax=Bacteria RepID=A4VJG2_PSEU5   E=4e-46 s/c=0.91 id=28% cov=79%
-IQIVHQDAALLVIDKPTLLLSVPGRAE-DNRDCLVTRLQENGYPEARIVHRLDWETSGLIVLARDADSHRELSRQFHDRETEKAYTALCWGQPDADSGSIDLPLRYDPPTKPRHVVDPELGKHALTFWRVLER-----------CGDHSRVELTPITGRSHQLRVHMLSIGHPLLGDRLYAHEQALRAHE------RLCLHASMLTLTHPQTGARLRFESPAP------------------------------------
>UniRef50_Q3YSF8(93-301:308) Pseudouridine synthase n=5 Tax=canis group RepID=Q3YSF8_EHRCJ   E=5e-46 s/c=0.89 id=31% cov=79%
---ILYEDDDVLIINKPAGVSVQGGTKVRISISDILDKIRD--GESMRIVHRLDKDTSGILMLARNARASRLIMHEFKNRRVEKKYLALTQGIPKNDvGEINHSITKKKHNFYENIGTGNSIFQEAITSFFVLKKLPYDIG----------LLELKPKTGRKHQIRIHLSHIGCSIIGDKKYGK------FCNHVLNDHLQLHAHFLSID--IGNKKLSFTAPMPDYMK--------------------------------
>UniRef50_C6CW89(95-309:322) Pseudouridine synthase n=2 Tax=Bacteria RepID=C6CW89_PAESJ   E=6e-45 s/c=0.85 id=31% cov=82%
-LTILHEDEHVIVASKEAGLLTIASDKETDMTAyrqLMAYVRESDPKNRIFIVHRLDRDTSGVLMFAKSEAVQQKLQEEWQTIVKERSYVALVEGEVKRQEGTISSWLKETKTLRMYSSPHPNDGQHAVTHYKLLQAGKV-----------FSLVEVHLETGRKNQIRVHMQDIGHPIAGDKKYG--------STTKPIGRLGLHARVLAFEHPVTGKLLKFDTGIPKLFYNPL-----------------------------
>UniRef50_C7MES4(103-316:318) Pseudouridine synthase, RluA family n=5 Tax=Actinomycetales RepID=C7MES4_BRAFD  E=1e-44 s/c=0.85 id=34% cov=81%
----LHEDEDLLIIDKPAGVAVHRGTDVPAGVIDALRQLRPEL-PDLELIHRLDRSTSGVLALAKSPSMLRYLHDLLRDRedEIERRYLALVAGHWPAETTILDAPLRREENR----VVVDPDGQRAETHVAVAQRF----------GNRATLLEVRLLTGRKHQIRVHLQHAGHPIAGDDRYGDDAFNR-RAASLGGTGLHLHAAELVIPRP-DGTTLAVTAPTPRRWEQLL-----------------------------
>UniRef50_Q9ZL98(78-313:327) Uncharacterized RNA pseudouridine synthase jhp_0682 n=15 Tax=Helicobacter RepID=Y745_HELPJ  E=4e-44 s/c=0.76 id=23% cov=89%
-IEVIFEDEDLLVLNKPPNLVVHKAPSVKEPTLVdwlksqNYELSNLGLKERYGIVHRLDKDTSGGIVIAKNNFTHVCLSEQLKTKMMGRYYIALLSTPLKEEKMSVECYLTRNPNNRLKMIALKAAKK------EKSRYSKSEFTSLLTSQNGMDLIGAKLFTGRTHQIRAHLEYLNRHIIGDNLYGLNGVLSKEEI-----RIMLHAYLIEFKHPRSEQKLRFKVPLLKDMLEYLKKVFDKENLDE------------------
>UniRef50_B0JGC2(300-500:501) Pseudouridine synthase n=2 Tax=Microcystis aeruginosa RepID=B0JGC2_MICAN  E=6e-44 s/c=0.89 id=32% cov=77%
-LEIIYEDEGIIAINKPAGLLSVAGRYQDSQDAVVNRFRRQ--GKNLIPVHRLDRETSGILLLAKSLDIYRCLSQQFQRREVEKIYEAILSEIIERESGIIDLPLWGNPQNRPYQTVDWQRGKASQTYFKVV-----------GKEGNYSRLEFIPYTGRTHQIRVHSQQgLGIGILGDRLYNGKQS----------DRLHLHAKQLSFRHPQTENKLDLIIPTP------------------------------------
>UniRef50_Q2CAH0(12-214:215) Pseudouridine synthase n=3 Tax=Proteobacteria RepID=Q2CAH0_9RHOB   E=8e-44 s/c=0.88 id=33% cov=78%
-LAVLHEDHEVVLVDKPAGLLSVPGKGEHLADCLLARVQAAF--PTALLVHRLDRDTSGVMIFALTPHAQRHLGLQFEKRQTRKTYVARVAGRIaDKTGTVDLPLIVDWPNRPKQM-VDHENGKPAVTDWRVVRASDAE-----------TRVRLFPKTGRSHQLRVHMLALGHPILGDPFYAEGPARAH-------PRMMLHSETLQFRHPDGGRGMRITAPAP------------------------------------
>UniRef50_Q7VI26(89-327:351) Ribosomal pseudouridine synthase n=1 Tax=Helicobacter hepaticus RepID=Q7VI26_HELHP  E=1e-43 s/c=0.74 id=24% cov=87%
-IDIVYQDEDVLIINKPPHLVIHHAPSVKEPTLVDWLKLNAHilytlsGEERYGIIHRLDKQTSGALAIAKSNLAYTTLTKELKSRQMGRYYLAIIDTPLKDNQQVQCFMGRNPHNRLKMSKIHIRSNSPIPKGVR--DSKSSFIKIATSDNGAFELIAIKLHTGRTHQIRAHLESLSRHILGDTLYGYKPQAKT---HYYQDRILLHAYILYFIHPKTQQNCTFKAPILPDMLKFLQ----------------------------
>UniRef50_C7PP03(7-235:247) Pseudouridine synthase n=1 Tax=Chitinophaga pinensis DSM 2588 RepID=C7PP03_CHIPD  E=1e-43 s/c=0.78 id=32% cov=83%
---IIKETADFVILNKPAGMLTIPD-RHDNQLDSLQGLLKKHYGE-IFTVHRLDKDTSGVILFAKNEVAHKYYSQLFEGRNVKKFYKGLVNGQLhPETGSVDEAIMEHPTIKGRM--VTNRKGKNAQTDYQVLEAFGL-----------YSLVQLQIHTGRTHQIRVHMKHLGHPIAVDELYGTAAPvylsaikknyklgKRVEEERPLLSRLGLHAWQLQFKD-QQGEENVIEAPLPKDIQAVVTQL--------------------------
>UniRef50_Q1RJX7(92-301:301) Ribosomal large subunit pseudouridine synthase C n=14 Tax=Rickettsia RepID=RLUC_RICBR  E=1e-43 s/c=0.85 id=28% cov=80%
----IYEDDNIIAINKPAGLATQGGSKINLSVDSALKYLNSQ-GADFKLVHRLDKETSGLLLIAKNYVSSVKLHDAFKEKLVEKTYLAVTYGKPiKDQGEVKTNIEKSKGSIPKITDINDNNGKLAITYYKLLKSL----------TNNLFLVEFIPITGRMHQLRLHAKLLGCPIFGDNKYGNDKLMPYSKY------MFLHANNIVLSKKVFGKEVNLEAKLPSYF---------------------------------
>UniRef50_D1AVV4(72-288:289) Pseudouridine synthase, RluA family n=2 Tax=Fusobacteriaceae RepID=D1AVV4_STRM9  E=2e-43 s/c=0.82 id=29% cov=82%
-LDIVYEDDDLLIVNKEPYLLTHPTLKKVDKTLANGIVYHFIEKYNknlvPRFISRLDMNTSGLIMIAKNSFSQSFI--QSGKANVTKKYLALAENMFEKEEIIVEEKIYKDGDELARII--DDRGQYAKTKFKLIKN---------YPHLDISLIECELFTGRTHQIRVHLKHLGHPIIGDSLY-----NPDSIFNKIAKRQMLHSYKLSFTHPSSGKRIDVEIPIYHDMLDILK----------------------------
>UniRef50_C6J215(83-309:310) Pseudouridine synthase n=1 Tax=Paenibacillus sp. oral taxon 786 str. D14 RepID=C6J215_9BACL  E=4e-42 s/c=0.76 id=29% cov=83%
-LSLLYEDDFCLVVHKPAGLKVHPDGNEggasrrdsaPPDTLanrVAGWYASLGQPIAAAHIHRLDEYTSGPVLFAKNEYAHLKLDEAMSRKEIGRTYIAFVQGVVSSAlKIIDQPIGRDRHHNQRR--RVSPTGKPAITHVELMEV---------YPKHEVSLVRLTLETGRTHQIRVHLSAAGHPLVGDALYGGSTKW--------LPYQALHGERLVFPHPLTGETVELDDPWPSAIIQLRDRF--------------------------
>UniRef50_A9E330(79-285:300) Pseudouridine synthase n=1 Tax=Kordia algicida OT-1 RepID=A9E330_9FLAO  E=7e-42 s/c=0.84 id=34% cov=78%
VISVIFEDDEIAIINKPAGF---PTNGNYFKTIENALPHNLKPSnsidalPFPKPVHRLDNPTSGILIIAKTKSAQISLYQQFEQQEISKTYQAIVIGKTDKEGEITSAVAE----------------KEALTNYETLQTV------SSLQNGHLSLVKLFPKTGRTHQLRIHLASINHPIVGDQLYGKAEENYK-------KGLFLCATSIQLIHPKTKEKLVFTIHPPNKYKSLLAR---------------------------
>UniRef50_A0Z298(103-318:320) Pseudouridine synthase n=1 Tax=marine gamma proteobacterium HTCC2080 RepID=A0Z298_9GAMM  E=1e-41 s/c=0.80 id=30% cov=83%
---IIREESTLLVVNKPPGLAVHGGSGINVGLIETLRAM-YETDRYLELVHRLDRDTSGLLLVARRASTLRNLHVLLRSNGIDKRYLCLVNGrWPAHLKRVDAPLEKFALPSGERRVKVAATGRQSLTTFRVVRRWSS-----------ATLVEAKPVTGRTHQIRVHCQHAGFPILGDAKYADEAAVRI-ADKLGLKRLFLHAASLNFR--LDDQNYSLEAGLPTELERLLD----------------------------
>UniRef50_C9RJ15(83-321:321) Pseudouridine synthase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RJ15_FIBSS  E=2e-41 s/c=0.72 id=26% cov=87%
-FETVFEDDEFILVAKPAGVPVHHTGRIFYNT-FAAIIRREFDSETATPMHRLDRDTGGLILFARYGETAARFQKNLDRILLRKFYLAVVRGKFPEgEVECHMPLREDPEDPIRLRMHHREGGKECFTRFKLVRHLDCPEIAP-----ELSLVEAELITGRKHQIRAHLAEMGYPIVGDRLYYrdgefyqklaqGGELTDEDIKVLGAHNQMLFAYKVELQLPYWKEPRTFEShAYPADMAKLLAE---------------------------
>UniRef50_C8Q1E7(37-242:243) Pseudouridine synthase n=1 Tax=Enhydrobacter aerosaccus SK60 RepID=C8Q1E7_9GAMM  E=2e-41 s/c=0.83 id=30% cov=80%
----LYRDDDIWVIDKPHGLLSV----DGKELKVSLQSRLLKADPNVKLIHRLDMDTSGIIIFARHSEAQTHISKQFIDRIPSKEYQALVWGTPPQQGEIDVPVRYDPPQKPKHIVDMSWD-KRAYTKYETLHH-------ELREGKAVSRVALYPVTGRSHQLRVHMLHIGHVMLGDPIYAQDVLN--GQAFDLSPRLCLHARKLRLKHPNTGVWMEWESPVP------------------------------------
>UniRef50_C7PHX6(368-568:570) Pseudouridine synthase n=1 Tax=Chitinophaga pinensis DSM 2588 RepID=C7PHX6_CHIPD  E=2e-41 s/c=0.85 id=31% cov=76%
-LDIIYQDESVVVVNKPSGLRSVPGVTIQDSVYT--RLKHALGDIEPLIVHRLDMDTSGLLVVAKTQAAHKHIQRQFLQRTVSKRYTALLSKVIDTsEGEIDLPLTADLFNRPRQIVCFT-TGKKSVTRWKVVTRYQA-----------MTKIDFWPLTGRTHQLRMHSAHplgLNAPIVGDDLYGTAAE-----------RMYLHAAHIEFTHPLSRQRISFDAPV-------------------------------------
>UniRef50_Q1GB64(79-296:302) Pseudouridine synthase n=17 Tax=Lactobacillus RepID=Q1GB64_LACDA   E=4e-41 s/c=0.78 id=30% cov=81%
-LDIVEETADYLVINKPAGLLSIPSGFHAEDAVinrVLAYFEKQGVNPayvKPHIVTRLDQDTSGLVLLGKNAIAHDRFSKLGKDAFIKK-YHAIVHGNFaegDLSGLIDKPLARVGDTVKRE---VNPKGQRALTEYRVLNQV-----------PGASLVELRLLTGRTHQIRIHMASIGHVLYGDDLYG---------ARDAFARQALNCFYLAFPNPFSGEEREIEIPDPGDMQGLWRQL--------------------------
>UniRef50_B8GBL0(78-307:307) Pseudouridine synthase n=3 Tax=Chloroflexus RepID=B8GBL0_CHLAD   E=6e-41 s/c=0.74 id=28% cov=84%
--HIIYEDDDLLVINKPPACYTGDTPWDTQGSVLAVARRllteRDGLVPTLHLAHQLDAGTSGILVISKHPRANAPLQAAFNHGQVDKRYLALCAGHPPTATELITGHGRAAAGRWRlyeqaeigKVLPNGQRVKRAHTQIEL-----------RRQYGDVALVWAKPLTGRTHQIRLHLVALGCPLLGDERYGG----PTTVAGMLIPHPLLHAAELALPHPRSGRLLNIFCPPPSIFTGVLKCFG-------------------------
>UniRef50_C4ZBX3(5-244:244) Probable 23S rRNA pseudouridine synthase n=1 Tax=Eubacterium rectale ATCC 33656 RepID=C4ZBX3_EUBR3  E=1e-40 s/c=0.70 id=27% cov=84%
--DIIYEDNDIIICYKPAGIATQTRRIGQQDMESFIRNYRaaKNEPPYVGIVHRLDQPVEGVMVFAKNQKAAASLSRQIKEHTTEKYYRAASRGqgvsgadkeednHDSAWHTLTDYISFDKRTNTSKITSEkDRLAKKAVLQYRVISV--TPDRDSSQNECIRTEFDIKLLTGRHHQIRLQLAHIGYPLIGDTKYGKPASNNSGTGSKSgrtcggvREQLALCSYKIVFDHPATGERMTFELP--------------------------------------
>UniRef50_C0QYU1(96-334:345) Pseudouridine synthase n=2 Tax=Brachyspira RepID=C0QYU1_BRAHW   E=1e-40 s/c=0.70 id=23% cov=83%
---IVYDDGDLIIANKPANLPVIPSGKYYHNTL--HTIVKNMLNSNINMLNRIDRETSGCVVLSRSSKSASNFCAMLAGRKVngkqykrnsiKKTYIAVIENAkdIEDKFTVEGYMLESGHEYYRRFQTLHkenvEGSKYSKTSFKTIKRI-----------GDYAVVMARLYTGRMHQIRVHLYSKGFFMVGDKIYGKYGPKvfddfieKGIIPEGFFNRQALHAYSLKFNHPITDEIIKVKAPLPKDLKEL------------------------------
>UniRef50_B0S0X9(84-316:321) Pseudouridine synthase n=2 Tax=Finegoldia magna RepID=B0S0X9_FINM2   E=1e-40 s/c=0.72 id=29% cov=84%
-LDIIYEDDDLILINKKTGVLSHAANPQDYGKnivdmMVSYLIKTNQFKPtqnstfTPALVNRLDRNTSGIVVGAKTYDSLKYFNDLFKKHEITKIYETIVVGNLK-DQTIDLALEKDNDKNKS---VINSSGKKSMTKVWNVKNF-----------GKYSLVNVDLLTGRTHQIRAHLSHINHPIIGDIKYGNREVNKYFKNKYDLNFQLLHSYKLVFPEKMGKyqkyESMVFESKRDDLFEKILNDL--------------------------
>UniRef50_C5RCG6(85-292:297) Pseudouridine synthase n=1 Tax=Weissella paramesenteroides ATCC 33313 RepID=C5RCG6_WEIPA  E=2e-40 s/c=0.81 id=26% cov=80%
-LQVLYENDELMVVNKRKGVKTHPNSPGENGTMMNfAQAYLMKQDKRAYMVHRLDGQTTGALIIAKVPYVVPILNQMLHDKTIKRTYLAWVDGHLTDSTGAITLAIGDHPTNSRLRQIDGANAKPAITHWTKIKSVYQQ-----------TLVRLQLETGRTHQIRLHMAAIGHPLVGDDLY--------NQQSAYADGLLLHSASVQLPMPFSSEIKSIGAPLPASF---------------------------------
>UniRef50_Q1UZE2(92-302:304) Pseudouridine synthase n=3 Tax=Candidatus Pelagibacter RepID=Q1UZE2_PELUB  E=3e-40 s/c=0.79 id=29% cov=79%
---IIDNNDDFIVLNKSSGISVQGGTKSKKNLVDIFARSEIFQDTKPFSVHRLDKDTSGVFIMAKHRQSAQLLTSLFRLRKVHKTYLAICHGELQKDSGEWNDDLTRYDNDREVVEK-------ARTLYKVLDKNSI-----------CSLVEMKPITGRKHQLRKQLYAVGCPIYGDQKYKFSNTDKAINKN-----LMLHSYQIKFM--INDKKYTYTALLPDYFKKLLK----------------------------
>UniRef50_C7H3U7(78-303:305) Pseudouridine synthase n=2 Tax=Ruminococcaceae RepID=C7H3U7_9FIRM   E=5e-40 s/c=0.73 id=28% cov=79%
-VRVVYEDAFAVVLEKPPHLAVHPTLNYPRDTLANgyaAWAVAHGESPVFRPVNRIDKDTSGLVLAAKNGYAAPLLAE-----GVEKLYYAIVEGELPlGPGVIDAPIGRRGDSIIGRCVTPE--GKPSRTEYTILR-----------AAQGLSLAACVPVTGRTHQIRAHFASIGHPLAGDDLYGGHRD--------RIARQALHCARQSFRVPAytevpggirletpvgeHARTIAVESPLPEDMRALLD----------------------------
>UniRef50_B1XN95(339-536:538) Pseudouridine synthase n=1 Tax=Synechococcus sp. PCC 7002 RepID=B1XN95_SYNP2  E=5e-40 s/c=0.84 id=32% cov=75%
-LEIIYEDHSLIAIHKPAGLPSIPGRSSQTYDSAFSRLRRDY--QDIFLVHRLDQDTSGILLFAKNAETQQDLQTQFRRRKIHKEYEALLEEKIQRPEGMITLPLWADPGDRPRQKVDAQRGKPSETYFVKLDSHR---------------LKLKPITGRTHQLRVHCAHpngLNNPILGDRLYGNRA----------APRLHLQATALTFMHPETKNPHTIQS---------------------------------------
>UniRef50_A4CLQ5(11-231:236) Pseudouridine synthase n=16 Tax=Bacteria RepID=A4CLQ5_9FLAO   E=1e-39 s/c=0.75 id=34% cov=80%
-LMVLYEDNHLIAVSKRAGDIVQGDKTGDTPLPEtvkdyIAHKYQKPGKVFLGVVHRLDRPTTGVIVFARTSKALSRMNRLFAEGGTRKTYWALVGTPPPETAGRLVHWLERNQKQNKSYARakEVPGSKQAILNYRLLGSLD-----------RYHLLEIDLETGRHHQIRAQLAAIGSPIKGDLKYGFPRSNPDG-------GIHLHARRLEFIHPVRQDPVSILAPLPDD----------------------------------
>UniRef50_A4ANB8(104-307:308) Pseudouridine synthase n=3 Tax=Flavobacteriales RepID=A4ANB8_9FLAO   E=2e-39 s/c=0.81 id=33% cov=78%
-LKMLYEDEHLAAIHKPSGILVSGNSFKTITHALSQNLEPSNLPDStlPQPVHRLDYATTGILLIGKTSSVIRALNGMFERKEIKKTYYAITMGKMEIRGEVTLKI----------------DNKNAQSKYVVEETV------PSERFGQLNLVKLTPITGRRHQLRIHMSGIGNPILGDSDYGTKDLILKG------KGLYLHAYSIEFNHPYTNEKLLIKSEFPKRFKKIF-----------------------------
>UniRef50_P72970(61-276:291) Uncharacterized RNA pseudouridine synthase slr1592 n=1 Tax=Synechocystis sp. PCC 6803 RepID=Y1592_SYNY3  E=2e-39 s/c=0.76 id=29% cov=83%
-LSVLHRDEDLWAIDKPSGLPVLPGGDFVYHTVLEQLKIQ-YPQESLFPLHRLGTGTSGLLLLGRSTLGRRELSRQFREHICRKIYRtVIGPCDLPEKFECHQAIGKIPYPQLGYIYAASSHGKPAQSYGRILAR-----------SPEKTWLEVEIRTGRPHQIRIHLASLGYPLLGDRLYGPGGVPINCRTARPSDGGYtLHSYQLGFLHLHTQQAIKLTAPLPPEL---------------------------------
>UniRef50_Q1VZ16(87-290:292) Pseudouridine synthase n=1 Tax=Psychroflexus torquis ATCC 700755 RepID=Q1VZ16_9FLAO  E=3e-39 s/c=0.80 id=30% cov=77%
-LKVIFEDDSMAVVNKPEGY---PTNGNYFKTIENALTYNLKTSsekdklPYPQPVHRLDNPTSGLLIIAKTLSSKSYLSVLFEHNKVHKIYLAIVEGHFE---------------GLSDIISLDIDGKQSSTNYGVEKMFKINQ-------DEFSLLSLKPSSGRTHQLRIHLSKIGHPIVGDKTYGSL---------TLSNKLMLHASSLELRHPKTDKSLSFETEVPHKFVKFINR---------------------------
>UniRef50_Q12362(161-346:591) Diaminohydroxyphosphoribosylaminopyrimidine deaminase n=25 Tax=Saccharomycetales RepID=RIB2_YEAST  E=6e-39 s/c=0.88 id=27% cov=65%
-IDIVFEDEDILVIDKPSSIPVHPTGRYRFNTITKM--LERQLGYSVHPCNRLDKPTSGLMFLAKTPLGADRMGDQMKAREVTKEYVARVKGEFPIGIVEVDKPVRSVNPKVALNAVcemSDENAKHAKTVFQRVSY-----------DGQTSIVKCKPLTGRTHQIRVHLQYLGFPIANDPIY-------------------------------------------------------------------------------
>UniRef50_C1E9U3(213-540:545) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E9U3_9CHLO   E=1e-38 s/c=0.49 id=28% cov=90%
-LDVIHEDDDVLVVNKPPGLRFHPVHRFEGNSLLSRAIGHvrrsgrdddrldgdaagDGHAHVPHVVHRLDMDTSGVCVLVKRPELVDGFARQFRgdagERRAVKEYLAIGVGaappgvtgcvvkadwkppeasgneqttaaefigveftvdahvgphasIPEARAVHRPPPTPERIPKRNGSGGDPDAPKPARTDVRIVSSSRVPIDVNDDGDVMQSltavLARVRLHTGRTHQIRVHMAHADLPILSDPLYGPHIRWDGASPcadastsailppgvdadvwggPRWLGRQALHAARLTLRHPETNEEMTFEARAPEDMRGACVALG-------------------------
>UniRef50_A1ZQW5(80-286:297) Pseudouridine synthase n=1 Tax=Microscilla marina ATCC 23134 RepID=A1ZQW5_9SPHI  E=1e-38 s/c=0.78 id=34% cov=78%
-LEVVYEDDHFAVINKPAGVKV---SGNQYRTIVNMLPGNLKASPLPdalkwaKPVHRLDVPTSGLLMVAKTTQAHIHLGQQLEQKTIKKAYHAIVKGTPAARGHIRTPI----------------NGQSAHSEFEVLQTV------PSLRNETLSLVRLSPHTGRTHQLRVHLASLGHPITGDTTY------DEAGNTMLHKGLFLAATSLQLQHPTLTQTIEVSIDIPHKFASLLER---------------------------
>UniRef50_A9GP63(19-261:666) Putative uncharacterized protein n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GP63_SORC5  E=3e-38 s/c=0.66 id=35% cov=80%
---ILAEDGDLIVVDKPAGLSTHAPEAERIDDMVtrlrAFLRGRGDAEAYLGIHQRLDRDTSGVLLFTRRREANAAVARQFEGRTVQKTYVAAVSGFGDRPPRGTLRHRLVPAPGGAMRALAESGGARedraakredraagredraakredraasgvlAITRYRLLERR-----------GDRALLELRPETGRTHQLRVQLAAIGLPIAGDPLYGGPE----------APRLLLHAAELRLDHPATGAAATFRSRLPAVFEAWLA----------------------------
>UniRef50_C1ZCX9(21-258:269) 23S RNA-specific pseudouridylate synthase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZCX9_PLALI  E=4e-38 s/c=0.67 id=30% cov=84%
---ILLEDGPLLAIWKPAGLLTQGVPQGLPTLEnwvknWIREKYAKPGNVYLGIPHRLDRPVSGVMLFARNSKAAARLAEVFRDRRVKKTYTAVVEGMPPQtTGRLTNYLLKDPQAAHSQIVAEGtPGSKSAILDYRLLGTV-----------AGRSLLEIELQTGRMHQIRVQMAAMGCPVVGDQEYqtpqagdtttrtvEEQSTTNLTTQPRGSERIALHASQIIVPHPIRFDEVTIHAPFPAEWASYW-----------------------------
>UniRef50_UPI000050FD43(98-326:332) ribosomal pseudouridine synthase n=1 Tax=Brevibacterium linens BL2 RepID=UPI000050FD43  E=6e-38 s/c=0.70 id=25% cov=84%
-ISVVFEDDDLLVVDKPHFLASTPNGRFVRE-CVVTRARLDFDQPDLVAIHRLDRVTAGLLILSKRPETRGRYQRLFQDRLVTKTYRALAAMPPADLELPLVKESRLVKPRGGRQVLEVEGEPNAFSKISLLGERTPPsprWSDATEPPPRRSVGECpsigeyqlEPLTGKTHQLRVHMNSLGLPILGDPVYPVDRAPDPYDFSSPLQ---LLAASIGFDDPLTGRPRRFESGL-------------------------------------
>UniRef50_B6IR13(11-197:242) Pseudouridine synthase n=1 Tax=Rhodospirillum centenum SW RepID=B6IR13_RHOCS  E=6e-38 s/c=0.86 id=31% cov=72%
---VLHRDADVLILDKPHGLPVHYGTKTVEHLEQYLPWIAFEREEPPRLAHRLDKDTSGCLVLARDAEVAARLGRLFLHGHVGKTYWAVVLGRPRGDAGRIDLPLLKVHIPGCSKVVVDPDGKPALTDWRLLAT-----------DGRLSWLELTPRTGRMHQLRAHCACSGFPILGDPIYG--------AEQPPPVPLHLHARTVSF----------------------------------------------------
>UniRef50_C7NCB1(72-378:380) Pseudouridine synthase n=3 Tax=Fusobacteriaceae RepID=C7NCB1_LEPBD   E=6e-38 s/c=0.52 id=28% cov=83%
-LDIIFEDEDILVVNKEPFLLTHPTQKKADFTLangiVNHFFEKYGEVRVPRFYNRLDMNTSGLIIIAKNSFAQAFLQN---FSIFEKKYLAIVNGIIDDKGIarINEELAKDGEKHKiqdlekenlksevekinfgkvkkyeeiekiesnlnvenedskiaentnfdnkdnnlnlanksnfenenlkenktkiiieRRIFRDGENleriidtrGQYAKTAIKVLKV---------YPEKNVTLVECELFTGRTHQIRVHLKSIGHTIVGDELYGNG-----LNKELGINRQFLHAYKVKFIHPALKKEIELEIPMFKDMKEFLE----------------------------
>UniRef50_C4XN86(119-308:339) Pseudouridine synthase n=2 Tax=Desulfovibrio RepID=C4XN86_DESMR   E=7e-38 s/c=0.84 id=29% cov=72%
-LEILHEDDELLVVVKPAGLPVHPGSGHTFALTTLLHAHAPHAPFKPTPAHRLDRDTTGLLLVAKSYRRLRALHEAMQDGTLRKDYFAWVWGKWLLGEENEWVTMRDalakSGGPGRERVTAGEDGKEAVAKVRLISRAPT-----------ASLVEVRLETGRTHQIRAQLASRGYPLVGDAKYGG-----------GPTPLRLHAWRVILP---------------------------------------------------
>UniRef50_A9B0U7(66-289:312) Pseudouridine synthase n=1 Tax=Herpetosiphon aurantiacus ATCC 23779 RepID=A9B0U7_HERA2  E=7e-38 s/c=0.71 id=27% cov=81%
--DILFEDEWILVLNKPAAWYSVATPWDTFGHLEGALQRffleRDGEAVPFHLVHRLDHGTSGALIVSKNPSLNSRFQRMFNEGRVQKTYLALCSGLPDWtklevvtghsRGEFGLWSVYPAAMIDQLYGPKDRRVRRAHTSFTVQAVGNAAALLAA-----------RLHTGRTHQIRLHAKHIGHPLVGDQRYGGVTQFG----NLSIPDQLLHAAWLQFPHPRYGSMLELIAPVPSLW---------------------------------
>UniRef50_Q96CM3(99-359:377) RNA pseudouridylate synthase domain-containing protein 4 n=19 Tax=Amniota RepID=RUSD4_HUMAN  E=7e-38 s/c=0.61 id=33% cov=85%
---ILHQDKNLVVINKPYGLPVHGGPGvqlcITDVLPILAKMLHGHKAEPLHLCHRLDKETTGVMVLAWDKDMAHQVQELFRTRQVVKKYWAITVHVPmPSAGVVDIPIVEKEaqgqqqhhkmtlspsyrmDDGKMVKVRRSRNAQVAVTQYQVLSSTLSS-----------ALVELQPITGIKHQLRVHLSFgLDCPILGDHKYSDWNRLAPQKlsvgtlKKLGLEqskaryiPLHLHARQLILPALGSGkEELNLVCKLPRFFVHSLHRL--------------------------
>UniRef50_B7G8W7(1-234:235) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G8W7_PHATR  E=7e-38 s/c=0.68 id=33% cov=79%
-LQIVYHDSDIVVVNKPPDVLTVPG---IHSRSCVLDLVHDRFGEAVQdkahmIVHRLDMATSGIVLFGRTLNITKRMQAIFRDRLVLKTYQALLMGHFPIDkGTIDLPLQRDHEYPPFMRISTptseadavqavkdlqqhgwkkliRKKPKPSQTSFRVLAR-------SFRNGLPFTRMELVPVTGRTHQLRVHCAALGYPIVGDPTYDEYVPNEKA--------MCLHAALLQCEHPTTGMPIVFEASPD------------------------------------
>UniRef50_B0G9B7(24-244:249) Pseudouridine synthase n=2 Tax=Clostridiales RepID=B0G9B7_9FIRM   E=9e-38 s/c=0.72 id=26% cov=82%
-INILYEDTQILVCVKPAGVATQSKRIGSPDMVSLLKNHismtsGKSGEPYLAVIHRLDQPVSGILVFAKTPAAAKDLNRQLTTSGFGKHYYALVAGTPePTSADLENFLVKDARTNTSRICQKGtADAKLAKLHYDLVDTTFFADIASSIPVA-TSQLKIKLDTGRHHQIRVQLSGMGCPIIGDTKYNPDSPKLTARRTP----LCLCAYQLEFRHPVTKKAMTF-----------------------------------------
>UniRef50_B8I5R6(76-267:303) Pseudouridine synthase n=2 Tax=Clostridium RepID=B8I5R6_CLOCE   E=9e-38 s/c=0.83 id=31% cov=73%
-FSVVYDDDNLLIVNKETGIPVHPDKNQKEATL--IDKLQSIYGPNLALCHRLDRNTSGLVIIAKNPATLEVMLEKIKNREIQKYYTCIVSGKMEKKNAELVDYLEKNEKLSRVFINPEKtrNSVQIITRYRILASMNSLN-----------LLEVELVTGRTHQIRAHLAYYGHPIIGDGKYGKNAENK----QYNAKYQLLCASRLTF----------------------------------------------------
>UniRef50_A0LBW6(12-221:224) Pseudouridine synthase n=1 Tax=Magnetococcus sp. MC-1 RepID=A0LBW6_MAGSM  E=1e-37 s/c=0.75 id=26% cov=81%
--HILHMDADLLIFNKPNRMPIYRGPGGGETLADHLPQLCFERGKPPAAVHRLDSATSGCLVLGRHKGMRRSLSNLFAQGGVEKLYWAVVQGRPLMDQGLIELPLQDVGWPGRPRVKVRMGGKWGRTLFQVMGY-----------GQNETLLALMPQTGRTHQLRVHCAAMGCPIVGDPLYGGAACDG--------PPMHLHARRI-LLHGAIQQ--SFTAPAPPHLQRFLEQ---------------------------
>UniRef50_C7ZA60(191-395:525) Predicted protein n=1 Tax=Nectria haematococca mpVI 77-13-4 RepID=C7ZA60_NECH7  E=1e-37 s/c=0.77 id=31% cov=70%
-LQVIHEDEDMIVINKPAGVPVHPAGRYNYNSVIEIMKSERGQGFLPYLCNRLDRLTSGIMFIAKNPPAAEALGIKIKQRTVRKEYIARVMGKFPDgEVVCDQPILQISPKLG--LNRVRANGKTARTVFKRLAYYPPPDGEETEGDGRpktpeeeldekhhpwinkrgYSIVRCLPVTGRTHQLRVHLQHLGHPIQNDPIYANRR---------------------------------------------------------------------------
>UniRef50_A5CFM2(98-308:312) Pseudouridine synthase n=2 Tax=Orientia tsutsugamushi RepID=A5CFM2_ORITB  E=4e-37 s/c=0.74 id=26% cov=80%
------ETSDYIIINKPALLPTQGGSKISLSLDDAIKYLNKSFYYDFKLVHRLDRETTGLLIIAKNHGTAIKLSQAFLHHSIEKEYIAILQGVPSQLSGE---IITNITKTGDRMIETQNGGKVSITKYQV---------KAISINSQLSLVSFIPVTGRTHQLRVHAAKIGYPIIGDKKY----NISNTYYNYSLK---LHAAKICIPkHLFGNQRI-YYAPLPYQFQQVISTF--------------------------
>UniRef50_C7G8E5(9-217:221) Ribosomal large subunit pseudouridine synthase family protein n=5 Tax=Clostridiales RepID=C7G8E5_9FIRM  E=6e-37 s/c=0.75 id=24% cov=78%
---IIYEDEDIIVCKKPAGVATQTRRIGQADMESLLKNYRASKGELPYIgvVHRLDQPVEGIMVFAKNKEAAADLSRQIKTKLADKYYYAMTDGVPekKKGTLEDELLQNGKTNTSEVVERGTPQAKHASLSYEVVEQ-----------DGKHAVLRIKLDTGRHHQIRVQLAHAGMPIVGDKKYNFKENIAPSGGQ-----LALCSFKIAFRHPKTHRKLEFE----------------------------------------
>UniRef50_Q6MA84(5-214:219) Pseudouridine synthase n=1 Tax=Candidatus Protochlamydia amoebophila UWE25 RepID=Q6MA84_PARUW  E=7e-37 s/c=0.74 id=28% cov=79%
-ISIVYEDNHLFVLNKPAGLLTQPSGTAHDSLESqakayLKIVYQKPGNVFLEAVHRLDKPVSGIVVFGKTSKALTRLNASVRAKQTKKIYYAWVDSVPVDEQKTLENFLIHNDFQAQVVSSKHPQAKLAKLTYRVIERKSVG-----------ALLEIKLETGRYHQIRAQLAHLGCPIRGDIRYGSQYPFTPHA-------IALHHESLEISHPIHQETMLFQTALP------------------------------------
>UniRef50_C5TJ50(96-303:307) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=C5TJ50_NEIFL   E=1e-36 s/c=0.75 id=27% cov=78%
---ILHIDEHLIVVDKPHFLPVIPSGRFLRETLLTRLRLRSELQhlnvEDITPIHRLDKDTAGVMLLSLNPATRRDYQTMFQEKTVQKTYEAVAPTRTDLDYPLDLS-SRMERGEKFFLTRETEGEPNAHTTIELIENR-----------GAFSLYRLTPHTGKKHQLRVHMMSLNMPLMNDALYPNPLAAGDEDYDRPLK---LLAKRIEFTDPVSGEIRVFES---------------------------------------
>UniRef50_B1ZYD0(18-255:255) Pseudouridine synthase n=1 Tax=Opitutus terrae PB90-1 RepID=B1ZYD0_OPITP  E=2e-36 s/c=0.65 id=29% cov=86%
-VEILERDPNgLLALSKPAGVLSHPNEGKDQPRSLLTCHFDavaecyvwtpegAATSQRWWLLNRLDSATSGVILLAANEELAREIRAQFKRKQVTKVYQALVFGKPPRPVELWRDVVAVTKQGGQIRTTAGAGRVPAECRMSVVRSRGVGE-------GALALLQLEPRTGRSHQLRVQCAKRHVPIVGDQTYGDFRHNREFAKRTGEKRLFLHSLATRFEYAWKGRTHVFaaQAPLPAEFGQVW-----------------------------
>UniRef50_A8ZT51(14-222:258) Pseudouridine synthase n=2 Tax=Deltaproteobacteria RepID=A8ZT51_DESOH  E=2e-36 s/c=0.74 id=26% cov=79%
--PVLYEDNHLLALYKPAGLLVQGDSTGDPTLLELGRcwlkiRYNKPGKVFLGMVHRLDRPVAGVVLFCRTSKAAGRISAQFRDGVTAKQYVAVVEGVIPENEGRLANHIFRRGPTSHIIDVPTPKSREARLAFHVIDRTDSR-----------TLVKIDLETGRHHQIRVQFAHLGFPVVGDLRYGAPAPLPGRQ-------IALLARRLTVTHPTLGHALTFTSSFP------------------------------------
>UniRef50_C5ZYE3(72-302:319) Pseudouridine synthase n=3 Tax=Helicobacter RepID=C5ZYE3_9HELI   E=2e-36 s/c=0.67 id=30% cov=75%
-LKPIYENEDFALFNKPAQMLIHPKGRFFHHSL--MDEVREYFGTEASLIHRIDKETSGLVLVGKHKRSIVELGELFANNRIKKKYLALIKGKMcktskivgDFCLLMPLSLQEKGGDLSVRSVflgqnlrkdSKLLGFRDAKSEFEILGEF-----------GGNTLLKVYPITGRTHQIRVHLFSLGFPILGDPLYGCEDWQsreyldsefieenrdfglcaEKRKEYFGADRLMLHAYSLEF----------------------------------------------------
>UniRef50_Q6AJJ4(19-235:238) Related to ribosomal large subunit pseudouridine synthase D n=1 Tax=Desulfotalea psychrophila RepID=Q6AJJ4_DESPS  E=3e-36 s/c=0.71 id=27% cov=78%
-LPIVYEDNDIILVDKVAGLAT--TSRDKDNENTAYFRLTNYVKKgvakssnRVFLIHHVDKEASGLLIFAKTEKARRHLLDNWSDFNVS--YVAAVHGVPVQTEGVLRANLAENMIHKMYVTVAGEKTRPAETEYSLLQH-----------SANYSLLSLRPKTEVKHQVRVQLADKGHSIIADKIYGVKSDE--------MKRLALHAAHLTITHPHTKKEMSFESRVPGHF---------------------------------
>UniRef50_A7RM79(24-308:330) Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RM79_NEMVE   E=4e-36 s/c=0.54 id=29% cov=90%
--NVIFSNNDLIAINKPYGLPVHGGPGVVLSVAELLEEFAaiKNYQNKPELAHRLDKygtdytimliDCSGVLLLTRNKTAAQKIAEMFQSRMVKKRYLAVSVGVPRYEegtisipvgygrvGPWERIIIRQDLVGKTHKEITEAGFKQAITKFKILDENQST----------CSLLEIEPITGHKQQIRVHLAdALRCPILGDHKFSSDKPQPQVIPLRLLQllqisgvkgvdgkkgrirpwqrgqiPLHLHSHQLVLPKYHTGSDLVISAPLPKYYLDTLSRLNLH---PKRKKMNQS-----------
>UniRef50_A0QT71(87-286:291) Pseudouridine synthase n=1 Tax=Mycobacterium smegmatis str. MC2 155 RepID=A0QT71_MYCS2  E=1e-35 s/c=0.76 id=28% cov=77%
-IPVLYRDDDIVVVDKPHFLATMPRGGHVTQTALV-RLRRELDLPELAPAHRLDRLTAGVLLFTVRRELRGAYQTMFARGDVQKTYLAHAEGVPKIALPATLR-SRIVKHRGRLQAFEEPGEPNAETYVEAVGDG---------------LYRLTPRTGRTHQLRVHMASIGLPITGDPFYPTVIDVAPGDFSRPLQ---LLAKRLMFDDPVSGARREFVS---------------------------------------
>UniRef50_B7G0C6(1-215:216) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G0C6_PHATR  E=2e-35 s/c=0.70 id=31% cov=77%
---VIYSDLYLAIIDKPQGMAVQGGENQTLGRSDLLLPLALKPGtkvpwptqnsildsalTKPRVCHRLDAGTGGILVLAKTRVAEVKLKQCFADRACRKRYRALLYGKLPKQEGTIEA---------------SLSGKPAETHYSVLRYVRS------LDFGWLTLIDLRPVTGRKHQLRRHMQGMGHAIYGDQRYGPKLEPRPNEgSEDPHSRLCLWAMEIALPHPSTGEYKTFTLP--------------------------------------
>UniRef50_Q2BH25(12-206:238) Pseudouridine synthase n=1 Tax=Neptuniibacter caesariensis RepID=Q2BH25_9GAMM  E=3e-35 s/c=0.77 id=29% cov=75%
---ILTQTADFIIINKSPGISVHKDQGDEGLTMLLQRQLELD---EIFLIHRLDKVTSGVMVFAKNRETAADLSMQFQNREVEKFYLAVSANKPKRKQGLVCGDMEKSRRGSWKLLRSKIN--PAMTQFVSVA-----------MKPGFRLFLLKPSTGKTHQIRVALKSEGAPILGDNMYGGEE----------ADRTYLHAYQLAFT--LNEERYIFRA-LPTD----------------------------------
>UniRef50_A1KTA8(96-303:307) Pseudouridine synthase n=24 Tax=Neisseria RepID=A1KTA8_NEIMF   E=4e-35 s/c=0.72 id=25% cov=78%
---ILHIDEHLIVVDKPHFLPVIPSGRFLRETLLTRLRLRPELQhlnvEDITPLHRLDKDTAGVMLLSHNPATRGAYQTMFQNKTVWKTYEALALTRTDLPYPLDV-VSRLVRGEKFFTTQEVEGVPNAHTTVELIENR-----------GEFSLYRLTPHTGKKHQLRVHMMGLGMPLLNDALYPVLSEAGSEDYRKPLK---LLAKKIAFADPLSGRERVF-----------------------------------------
>UniRef50_Q7V4B8(97-329:338) Pseudouridine synthase n=2 Tax=Prochlorococcus marinus RepID=Q7V4B8_PROMM  E=4e-35 s/c=0.64 id=28% cov=78%
--EVIFDDGDLLVVNKPSGLPVIPGGGFLDHTLTGLLQRRCQLDGEsrlPRPVHRLGRFTSGLLICARQRETRAKLSAMFRRatagdQGCKKIYRALAHRNLNVHCdevaTIRVPIVQTAHPMVGKVWVAADSSRQHdskQSESRVLTALSTVRLLERRQDAD--LLEVAIQTGRPHQIRIHLAAIGSPLIGDPLYG-FDGQISSAATPGDGGYCLHAHRL------------------------------------------------------
>UniRef50_C5M016(1-259:417) tRNA pseudouridine synthase C, putative n=3 Tax=Perkinsus marinus ATCC 50983 RepID=C5M016_9ALVE  E=6e-35 s/c=0.58 id=25% cov=91%
-----------MVVYKPAFYRCQLPDDHPEDSIVSWLSRQYEIDPELMneelnpalsggggfgpMCHRLDKQTSGPVLIARKLESWKFIRRQFQKEQVTKRYVCLVDGICANDsGMIDSPIRvRRTEKHTSAEIGSGPASSSAHSEYRVLERYEE----------GCTLMSVRITTGVTHQIRVHMAQgLGHPIVGDKKYTPSGRGSELPCATRMPgRVFLHCYELGVkPDKTSGQKLtTIKCSLPTELRNLLWSLTPIStcPLPADTRALLAGLMGLPS----
>UniRef50_Q0IBH1(25-218:220) Pseudouridine synthase n=11 Tax=Cyanobacteria RepID=Q0IBH1_SYNS3   E=6e-35 s/c=0.77 id=31% cov=75%
----------FLVVEKPSGLLSQPGLGDSQSDSLITRLQA--VRPELRLVHRLDRDTSGLLLLARDPESLKVLGGLFAERKVHKFYAADVHGHPKsRSGAVRLPLARLSAHPPRYGPRRD--GRSCLTLWR-----------CAQMGSDRSRLWLAPRTGRSHQLRAHLAAIGLPIIGDPIYASSGLGSPGE------RLHLHALGLSFSDPFSGQRIRVRSSLP------------------------------------
>UniRef50_Q9LT72(185-467:477) RNA pseudourine synthase 4, mitochondrial n=2 Tax=rosids RepID=PUS4_ARATH  E=6e-35 s/c=0.53 id=31% cov=65%
---VLYKDPAIIVLNKPHGLAVQGGSGIKTSIDELAAsCLKFDKSESPRLVHRLDRDCSGLLVLARTQTAATVLHSIFREKTtgasaygvkknvksLKRKYMALVIGCPPRQRGQISAPLRKvvvDDGKSERITVNDNGelvsTQHAITEYRVIES----------SPHGYTWLELRPLTGRKHQLRVHCAEvLGTPIVGDYKYG------------------------------------------------------------------------------
>UniRef50_C8PJZ2(77-462:495) Pseudouridine synthase n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PJZ2_9PROT  E=9e-35 s/c=0.39 id=29% cov=85%
-VEILYEDDDLLVVNKPAGLTVHPAASVKEPTLVDWLKSRgyllstLGGELRAGIVHRLDKLTSGALLVAKNNAAHAALSAQLSDKSMGRIYLALIDLPLKEPCVIERPISRNPANRLKMGIV--PGGRSAKSAFyeilsgaeltelqnsaercdeilgagdgtaanasasristeekilgdamdkistgdankisavstgkdkilnasrdadasKILATHASANPNAGTDKilnnradnvdeisnncmqsadkiliqsadkipnnradnadkiltadmsadqtqtarlaenkalnfknpaqnyklppinlKSFNLVAAKLFTGRTHQIRVHLSSINRHILGDHLYGFKSENAK------ISRILLHAYLLYFIHPRSGKEVKICAGLPSEFLN-------------------------------
>UniRef50_A6QCU7(73-278:309) Ribosomal large subunit pseudouridine synthase, RluD subfamily n=1 Tax=Sulfurovum sp. NBC37-1 RepID=A6QCU7_SULNB  E=2e-34 s/c=0.72 id=33% cov=75%
----LFSNRDFMIFEKPSGVLVHPNTMSTPYS--MLDEIRHISGDNANATHRIDMETSGLLLASKHKKAETHLKNSFEAKTIKKSYLAWVDGRLNEPFSVSEKIKINNDYSRVKHKVfISDAGKASHTDFIPLRYNERL---------DATLVACYPQTGRTHQIRVHLFHVKHPILGDPIYGttfdtanryleDEISEEERFLETGARRLMLHAHTLSFT---------------------------------------------------
>UniRef50_C4PLV8(72-273:274) Pseudouridine synthase n=13 Tax=Chlamydiaceae RepID=C4PLV8_CHLTZ   E=2e-34 s/c=0.73 id=30% cov=71%
----LWEDEHLCIYNKPA----------KQTSEDLAHQL------NVHLVHRLDRDTSGCILFAKHAKASSLITQLFKNPEIDKRYIALVFGQPRQesgiITTYTAPCYRRTGAVLFGN-TDQNSGKITITKWEILTRY-----------PKYTLLLCRPVTGRTHQIRLHMKTIGHPIVGDVDYGNQEQPKNVV------RTLLHAASLAFISPFSNEKIEVSS---------------------------------------
>UniRef50_B8HC32(88-317:326) Pseudouridine synthase n=1 Tax=Arthrobacter chlorophenolicus A6 RepID=B8HC32_ARTCA  E=3e-34 s/c=0.64 id=28% cov=84%
-LSILHQDEHLLVVDKPHFLPTTPGGTYIQESALV-RLRNQLDLPDLIPMHRLDRMTAGVLLFSTNPQTRGKYQVLFEKRQVQKEYECVSAADPaPGHPAVEFPVVVRNRMTKSRSYLlaeVVEGEPNAETRIERLETFDggaspdtnGSTAAVPGSPTRLARYRLEPHTGKTHQLRVHMASLGLGIVNDAFYPDLLDKAPDDY---AKPLQLLARGIRLVDPISGSPVEYRSSL-------------------------------------
>UniRef50_B7VGV5(39-222:270) Pseudouridine synthase n=17 Tax=Gammaproteobacteria RepID=B7VGV5_VIBSL  E=4e-34 s/c=0.80 id=26% cov=71%
MFDILLNHSDFLLINKHPGVSVH---KDDGDTMLLQEVAKAINEPKLYLVHRLDKMTSGILLLAKDAPAASELSQLFAKREVEKYYLAIGSKKPKKKQGLISGDMERSRRSSWKLLTTKEN--PAITQF-----------LSATAEPGERLLLCKPYTGRTHQIRVAMKSIGSAIVGDPIYNPSNE---------ADRGYLHAFAIRFT---------------------------------------------------
>UniRef50_A1R0P0(110-296:331) Pseudouridine synthase n=20 Tax=Borrelia RepID=A1R0P0_BORT9   E=2e-33 s/c=0.78 id=28% cov=64%
---IVYEDADLLVINKRRGILVHGD-KYSLDTLINAYLLDESLGSlsfKPSAVHRLDRNTSGLIIFAKNINSARILSQAFSSGVVIKKYLALLDGVITKPLTYKNFLYRD-KIARKTFVINDIDKCNAVTDIKPILVSKSS-----------TLAEVSIKTGFTHQIRAQCAFNKHALINDKKY-------------------------------------------------------------------------------
>UniRef50_D2VTC2(412-619:624) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VTC2_NAEGR   E=2e-33 s/c=0.70 id=27% cov=76%
---ILFKNDEIIALNKPYGICVQGGSNQTFHIDALLDALtgLDGFNVRPKLVHRLDRDTTGVLIVARNRAGAIRMQQWLQESTVplKKCYWAVTVGVPTPttgRIKMVIDIQKDANGVEKVVPVDNKtdSSKISVSEYKTIDHM----------TDKLAWVALYPVTGRKHQLRVHCAsALGAPILGDYKYGEGVPESLTHvvPDKSLKRLHLHHRAMKLP---------------------------------------------------
>UniRef50_D2NPM0(136-369:377) Pseudouridylate synthase n=2 Tax=Rothia mucilaginosa RepID=D2NPM0_9MICC  E=2e-33 s/c=0.62 id=28% cov=83%
--PVLYEDEHVLAIDKPHFLPTTPRGAYIAQTALTKLRVREQ-NPLLIPIHRLDRPTAGVLLFAKTVEARRPFQMMFQHRRVSKTYRAVAPVPADPAAAERAlsaeglqvrsHIQKIRDQLQVQQLSEEQCAaqgvePNTLTTAKILQTFTPSaqavEGWRAEPNREWALYDLAPHTGKTHQLRAHLNMLGSPILGDVLYPQVLPDAPDRPEYPLQ---LLAYSLHFEHPITGERVDLYS---------------------------------------
>UniRef50_A6T3V4(107-310:316) RNA pseudouridylate synthase family protein n=11 Tax=Proteobacteria RepID=A6T3V4_JANMA  E=4e-33 s/c=0.70 id=28% cov=79%
---VLYQDDYLVAVDKPHFLPVTPAGRYLQETLLV-RLKRSLDIDTLAPMHRIDRETAGLVLFTIQPQTRNLYQTLFRERSVSKEYEAIAPLRADLE-LPTTYRSRLLESEAFMKMCEVAGEANSETAISLLETR-----------GNFGRYLLQPVSGQKHQLRAHMAALGIPIVNDRIYPHLYPDEGATQDYSQPLQLL-AKSISFTDPLSGKLHRFDS---------------------------------------
>UniRef50_Q6NEJ6(129-344:349) Pseudouridine synthase n=6 Tax=Corynebacterium RepID=Q6NEJ6_CORDI   E=8e-33 s/c=0.66 id=21% cov=82%
---VVYEDDTLLVADKPPFLATMPRGKHITNSATVQ-LRRSTGIDELSPAHRLDRLTSGLLLFTKRKRVRGAYQTLFSERNVRKTYVATAQYNPSITPGTIWR-SHMTKTAGEIQGHIIDAPPNAETLVSAIERIDAPTQQHLHALHGtdvdLAHYTLKPHTGKTHQLRLHMLAAGVPILGDTIYPTILAEDAEDYSRP---MHLTSTELEFIDPLTGRPRLFT----------------------------------------
>UniRef50_B2S1F9(99-285:320) Pseudouridine synthase n=2 Tax=Borrelia RepID=B2S1F9_BORHD   E=2e-32 s/c=0.75 id=27% cov=64%
---IVYEDEDLLVINKRRGALVHGD-KYSLGALINSYLLDENLESlsfKPSSVHRLDRNTSGLIIFAKNIDSARILSRAFSSGIVTKKYLALLDGEIKKPLTYRNFLYRD-RIARKTFVVNDEGRCNAITDVKPILVSKSS-----------TLAEVSIRTGFTHQIRAQCAFNKHALINDKKY-------------------------------------------------------------------------------
>UniRef50_D2Q929(36-257:264) Ribosomal large subunit pseudouridine synthase D n=19 Tax=Bifidobacterium RepID=D2Q929_9BIFI  E=2e-32 s/c=0.64 id=23% cov=82%
--EVLYEDDGIIVIDKPHFLATTPRGMWYRETA-LIRLRERYGEPDIVPAHRLDRLTAGVVVFVRKPELRGAYQMLFQEHRTVKTYECLAPLAPvvrPRYGTVTRIDRNQPFPLVRRSHIAKDRGRlqayeipAAVNAESLIERGDNPRIIDGNVVINYVL---HPKTGKTHQLRVHMNSLGLPILGDVFYPDVIQRPYDDFSRPLE---LVARRLEFDDPVTGESRAFVS---------------------------------------
>UniRef50_A8REN7(83-283:313) Putative uncharacterized protein n=1 Tax=Eubacterium dolichum DSM 3991 RepID=A8REN7_9FIRM  E=3e-32 s/c=0.70 id=27% cov=73%
-LDIVYEDENLLIVNKAKGLLAHRDQKVGQDNLmdriLHYLYIHKEYDPRmensfvPALCHRIDRNTQGLVIAAKNAASLRAMNAHIKQRKVRKKYVCIAQGVFDKRQEHVlLYHCKTKDNVAHILPYPKEGYKPIEINYQIKEQKK-----------QYALVEVELLSGKSHQIRAMLAYLSHPLYGDVKYGAKHTAAKHY-------QMLCAYRIEF----------------------------------------------------
>UniRef50_C4LE96(109-311:316) Pseudouridine synthase n=23 Tax=Gammaproteobacteria RepID=C4LE96_TOLAT  E=3e-32 s/c=0.69 id=25% cov=78%
---ILYMDEHLLIADKPHFLPVTPAGDYVSQTL-LARLVARLNNFELQPLHRIDRHTAGLVMFSVQKKSRAAYQALFRDRKIEKRYEAIAP-ALPQIAFPHIRATRIERGEPFFLSQETAGTANSQTIIDVIERRADLWK-----------YALNPVTGKKHQLRLHMSALGAPIYNDAFYPSVNDDVADDYQKPLQ---LLASELTFVDPVSGVKRHFKS---------------------------------------
>UniRef50_A5DIJ4(102-279:390) Putative uncharacterized protein n=2 Tax=Pichia guilliermondii RepID=A5DIJ4_PICGU  E=6e-32 s/c=0.79 id=28% cov=68%
-ISIIYQDPSLIVVNKPSGIPTHPSGNFRYNSVTEIVKAQLHL-ESIFPCHRLDKATSGILMLATTSAACSNIQKQLQERKdVKKEYIARVKGKFPPSQLVHQDPVFLLNSTAGYIMPGRYVSIDSSTTFTRLKYNSELDE---------SIVSCEPHSGKMHQIRIHLRNLGFPIVNDKLYNPGESDK------------------------------------------------------------------------
>UniRef50_P53294(119-317:404) Pseudouridylate synthase 6 n=8 Tax=Saccharomycetaceae RepID=PUS6_YEAST  E=6e-32 s/c=0.70 id=26% cov=65%
-FNIVFEDESILVIDKPSGIPVHPTGQFYQNTITELLKLH---GVDALPCYRLDKITSGLLILAKNSQSAGEIQKSIRSRDMIKIYLARVKGRFPHselildnenaaettfedtSKVTVEMTPIYSIDPKRQFPVGLSTSKDAITKFYPIRYFSHADE---------TVVACKPITGRTHQIRIHLARLGHPIVNDSVY-------------------------------------------------------------------------------
>UniRef50_Q7NAY8(84-291:330) Pseudouridine synthase n=1 Tax=Mycoplasma gallisepticum RepID=Q7NAY8_MYCGA  E=1e-31 s/c=0.67 id=27% cov=75%
-LDLIYEDENLVIFEKPLGIPAQqtdePSQYDHMQNRLVHYLVKSNQYDYLNnqaylpsIVNRLDTYTTGIMLGAKNLKAQQALNQIIKNRDLKKFYHCLVHGEInPKKATLTAYLTKDPNRSLVSIQKEKtNDNKIIITRYQTLYYFK---------KQNYTLLDVELITGRTHQIRAHLASINHPVVGDYKYAKKQYQNNQG---NFKHQLLHSYKIIF----------------------------------------------------
>UniRef50_B0SSX5(17-217:231) Pseudouridine synthase n=2 Tax=Leptospira biflexa serovar Patoc RepID=B0SSX5_LEPBP  E=1e-31 s/c=0.69 id=22% cov=77%
---IFYECDDFLLAEKPEGIPVHET-KDPSRMDFTRLLSNHLQIPELRTVNRLDLGTSGIVLLGKNKNKNVELDLLLK--EAEKTYIFLCDGIPSWREHRMECFLKEGN---KQVNLVRSGGKKAITEFSILHS---------DPNESISFGFAKILTGRRHQIRVMLSSLGFPILGDTVYGKKEKTET--------RMYLHSFRFYFTDFLGQKQM-VQTDVPRDW---------------------------------
>UniRef50_C8X2D1(1-232:237) Pseudouridine synthase n=1 Tax=Desulfohalobium retbaense DSM 5692 RepID=C8X2D1_DESRD  E=3e-31 s/c=0.59 id=27% cov=87%
MYETIAEDERFLCIHKDPGVDCHTD----NGSSGVIRAVQSAYRIRLFPLHRLDKVTSGLLLLAKDRETARSMGELFSAHRIDKFYLALSAKRPRKKQGTVIGDMRRSRRGTWRLERSREN--PAVTQF----------VSRAWSGGKRAFL-LRPQSGKTHQLRVALKSLGAPILGDPLYGPRNHSQ--------DRCYLHAMAVSFE--LDGERYSFWTPprhgehfLDPDGSEVLAAWSR----PEELAWPRIPGSGQPS----
>UniRef50_Q2SJX2(105-295:297) Pseudouridylate synthases, 23S RNA-specific n=1 Tax=Hahella chejuensis KCTC 2396 RepID=Q2SJX2_HAHCH  E=5e-31 s/c=0.71 id=29% cov=71%
---------------KPAGLLTQGSEWGDHCSLLRMAELHFQSKRQVFLLHRLDREAMGLVIIAHNKAAAGRFGALLQDNALDKFYLARVKGRLAQEQGEIDFPV---------------DGKSALSYYQV---------QHYDDATDSSLVRVKLITGRKHQIRRHFADLGYPLLGDPRYGSGNKHE--------DGLMLAATELAFTCPMRRRAMRVV--MPEALLPAWSR---------------------------
>UniRef50_A4B9B1(13-208:214) Pseudouridine synthase n=1 Tax=Reinekea blandensis MED297 RepID=A4B9B1_9GAMM  E=9e-31 s/c=0.69 id=34% cov=75%
--------DAYFVIVKPTGWTVQRDAQAPS----VLEWLNDQ-GHTAFPVHRLDKPTSGLLLVARTTEANRALSLGFAEGRVEKTYLAISDRRPRKKQGWVRGDMAPSRRSQWKLLREQNN--PAITRFRSVSLDDGERGFV-----------LYPKTGKTHQLRVALKSLGSPMLGDTLYGG----------TPADRLYLHAWRLAFD--FEGERLSYQAdPIDDKFTRWLSH---------------------------
>UniRef50_C4QA60(149-333:455) Ribosomal pseudouridine synthase, putative n=1 Tax=Schistosoma mansoni RepID=C4QA60_SCHMA  E=1e-30 s/c=0.74 id=27% cov=66%
-IEFVHDSDDILVVNKPPSIPIHPCGQYTLNSITHILA-KDYGLRPLRFTHRLDRMTSGLLLIAKNYDTSVRLQSQISSKEVAKYYICHVEGCFPTEPIdqctgfeinngvvvCSQPVGPISRRMGvHGVLPESAGGKFARTHFLRLSY---------NPVTDTSLVICRLFTGRTHQIRIHVQYLGYPIVDDPLY-------------------------------------------------------------------------------
>UniRef50_Q317H5(103-308:332) Pseudouridine synthase n=2 Tax=Desulfovibrio RepID=Q317H5_DESDG   E=3e-30 s/c=0.65 id=30% cov=76%
--------DGLLVINKPAGLPVQPGTGHTDCVTARLAAHFAGADFMPAPAHRLDKNTSGLLLAGTTYTALRTLQDLFRNgHSLIKDYCAWVCGIWPEQEalTLTDVLVKEGTPGKEKIHALPAGSAQPHTAP-PKGREALCQVVPLLRLDNATLLGIRLATGRTHQIRVQLASRNHPVIGDVKYGAPACRA---------GMLLHAFRLVLPAPFGRE---------------------------------------------
>UniRef50_A4S2M8(32-214:218) Predicted protein n=2 Tax=Ostreococcus RepID=A4S2M8_OSTLU   E=3e-30 s/c=0.73 id=31% cov=67%
-------------------------------------------GKHHRFCHQLDTATSGVVLTAHTREAAGNAAKLFRDRLAKKKYLAVVFGWPKeDEWTVNAKLGKDPTDVKgFRERVDEENGKASETSFKVLQRG-YCTLDGANRGVEVSRLECRPVTGRRHQIRLHLMHSGHPILGDMAYSDDTDSY---------RMFLHA--LELVMPFEEETLTFATEPPESF---------------------------------
>UniRef50_Q73KM2(5-216:236) Pseudouridine synthase n=1 Tax=Treponema denticola RepID=Q73KM2_TREDE  E=3e-30 s/c=0.63 id=27% cov=79%
-VRILFEDNFFAVVLK-----------NCGDNSQVFFKKAFSEKKYAEAVNRLDKPVSGLVLIAFSPAMHTKLNNLFKEKKIKKEYWAICKKIEELKSAADSKISDTTPVLYKKEFCEnylefnTKIQKAFVTESRQRGKKASLYWQLAGIGDNYNFLRIFPETGRTHQIRIQLSHLGMPIKGDIKYGFARTEKSGGIR-------LHAQSLKFEHPESKKRIEISALPP------------------------------------
>UniRef50_C4XWV4(146-316:432) Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC 42720 RepID=C4XWV4_CLAL4  E=7e-30 s/c=0.78 id=29% cov=64%
---VLYEDENILVVNKPAGVPTHPNGIFRRNSLT--EIVRFELGVSVYPCHRLDKGTSGVLVLAKT-KTGKMLQEvlQNKKSHVEKWYVARVRGKFPfasCSYTSPVFSINTAGTGYLNIPNAERVPATSSTHFKMVSY---------SPELDESIVFCRPISGKMHQIRVHLRNMGYPISNDPLY-------------------------------------------------------------------------------
>UniRef50_C4GD18(5-307:312) Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles DSM 14600 RepID=C4GD18_9FIRM  E=2e-29 s/c=0.43 id=26% cov=80%
--EIIYEDADIFVCYKPAGFATQTASALQADLVSELKNYRKSRGEsdYIGLIGRLDQPVEGLMVIAKNPRAAGKLEAAQAKGRIDKYYLALTQGlpkgpdcgqeadslhrkgewiflendmlpasrgkngrllapedkgtknghqpAPEDKGTKNGHQPAVKDKGAKKTRLPAPGTGEAKTACQlapgtgeakkacllapgikgarkaRLEYQILDHSKTK-DGRALALLRVHLLTGRRHQIRLQLSGLGSPILGDARYGADPNGQP---------LALCACQLSFPHPGTGERISYE----------------------------------------
>UniRef50_C7MAG2(79-292:305) 23S RNA-specific pseudouridylate synthase n=1 Tax=Brachybacterium faecium DSM 4810 RepID=C7MAG2_BRAFD  E=3e-29 s/c=0.61 id=26% cov=80%
-LRILHRDAHLLVLDKPHDMATMPRGAHVLSSALV-RLRRATGISTLVPLHRLDRRTAGVLAFGIRPEERSAYQQLFARQEVDKEYEALLVlgpgtSLPTAVGERAVLRDRLDKRRGELTTRVLDGPPNAETALEV-----------RAAGEGLLQVRLHPRTGRTHQLRAQLAARGAPILGEDLYRPAQDPPPPADAGGPDlPLQLLSRTLRFADPHTGVRREFTS---------------------------------------
>UniRef50_B5YM19(57-323:344) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B5YM19_THAPS  E=4e-29 s/c=0.49 id=26% cov=86%
-IPIIYENDQLLAVCKPPHISHHDDPaSNQLGLLSLIRLQQqqqqqqdessFPYPHRLHGVHRLDRVTSGVLLLAKDSSVANELITKFRQGEVSKYYMAISgkkpkkkkQGWVKGQMVMgrrgsyklvnenrdvlDEGDGDDEVEDGGEVSQVKKKGGYAVTRFYtaglgdlqlaPLPKCDGDESNDDELLIPKTAILFQPHTGKTHQLRVAAKSAGIPILGDVRYGGGTVTQ-REENANFDRTYLHASAIHFQ--LNDEDVTIWSPPPFD----------------------------------
>UniRef50_A6DFD4(6-222:231) Pseudouridine synthase n=2 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DFD4_9BACT  E=5e-29 s/c=0.60 id=28% cov=71%
--EVIEEFEDFILVNKKPGENFHSESGEEG----LFHQLKEHYGE-LYPVHRLDKVTSGLLLMARNLQSCQELNQLFEAQKIEKFYLAISDRKPKKKQGWVIGDMEKSRRGGWKLCESRKN--PAVTQF-----------FSYSIGQGKRVYLLRPRTGKTHQLRVAMKAIGAPICGDPNY------YPGLIKGHEERCYLHAYVIRFT---------------------------------------------------
>UniRef50_Q2JFI3(2-274:304) Pseudouridine synthase n=2 Tax=Frankia RepID=Q2JFI3_FRASC   E=6e-29 s/c=0.48 id=26% cov=80%
----IYEDEAILVLDKPVGISV---MGERHDTDLV--TLAGDDGEELFPVHRIDKVTSGLVLFARQLRFHGDLTRQFQRRTVDKRYLVLTRTRgLPASGTVDLPLSVGRKSRVRvaanradimadlaevaplaevadlgevaplaevaplaevadlgeaaplaeaaraevgptgagaGAGVGRWTVPPAAVFPHVRTYPSVTTFIRVWEGGEYTLLAVTPVSGRRHQIRVHLAWIGHPIEGDPLFGRDATA----------RTLLHSWRLAFDAAWaGGSRIEVEAPPGADF---------------------------------
>UniRef50_Q1MQF8(102-298:321) Pseudouridine synthase n=2 Tax=Bacteria RepID=Q1MQF8_LAWIP   E=2e-28 s/c=0.65 id=26% cov=72%
----------FIIFYKPAGLAVHGGTGQTDSLAHRLSQHYAHSTFMPTPVHRLDKDTSGLLLVAKTYNSLRYFSELFASHstQLTKEYLAWVVGICPWTQpICLEDILTKKQKQDNYSRLNSYQNKLQQTS----AQKASLTVRCIKQYKDKSLLLIKLHTGRTHQIRIQLSIHGFPIIGDKKYGN---------TIRSHNLKLHAFRLSFP---------------------------------------------------
>UniRef50_B0E5G5(146-333:402) Ribosomal pseudouridine synthase, putative n=2 Tax=Entamoeba RepID=B0E5G5_ENTDI  E=3e-28 s/c=0.68 id=28% cov=64%
-LTIVKETNDFIAIDKPSSVPVHPCGRYRHNT--VIFILSHEGYPNLRPVHRLDRMTSGILLLAKTIQAARE----FQNHMVikKKEYICRVRGKLEKTVVTSKIGRKRIDDKKIHVSVNkiEEDGKECCSEFNPLFYDE---------KTNTTVAVALLGSGRTHQLRVHLQSIHHPIVNDPIY-------------------------------------------------------------------------------
>UniRef50_Q4UIK0(136-350:441) (RNA) pseudouridylate synthase, putative n=2 Tax=Theileria RepID=Q4UIK0_THEAN  E=4e-28 s/c=0.59 id=25% cov=66%
-VPVVYEDDQYIVVSKPTSIPVYQTGTYNYNSLMeiMKREIPSCRDLKLFTVHRIDRLVSGLVAFAKSSQDASNLSQAIRDNEVKKVYIARVKGDFSYlintsnsdnkesdgdadnslenVFESIGYMRVISKKEGKYEFVgendEDESYKRSVTRFKLIKYNKDLHE---------SLVLCSPITGRTHQIRAHLKYLGYPISNDPWY-------------------------------------------------------------------------------
>UniRef50_A5DTZ4(107-279:430) Putative uncharacterized protein n=1 Tax=Lodderomyces elongisporus RepID=A5DTZ4_LODEL  E=7e-28 s/c=0.73 id=22% cov=66%
-ISVVFEDDDIIVIDKPSGIPVHPTGSYMFNSLSEIVKEMFNFD-NIWTCHRLDKVTSGVVILCKNRDAAVKFLNILleKSDKVKKIYLARVNGKFPDgVYRYTCPILAVNMNGYI---------QPSNLESLLTLTSTIFERVNFDSLSNTSIVRCQPISGKFHQIRIHLRNLGFPISNDLFY-------------------------------------------------------------------------------
>UniRef50_A9FG19(82-319:326) RluD4 protein n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9FG19_SORC5  E=2e-27 s/c=0.53 id=25% cov=82%
----------LLVASKPAALPTEPERRGTRSLVTEVAEL-LGLRDLPHAASRLDVGVSGAVLCATGARGRRHVVAMREAGRIARVYVGVAGGRVEGSGTWDAPIGaARARGGRSLPAVGGADAKDASTHYR-------AVASAGGGAAPATLLRLDPVTGRTHQLRVHAAHAGAPLLGDRDHGGARSVTTARGRvIPLSRVALHALRVTVPD-ERGELCAAIAPVPDELRELW-----------------------------
>UniRef50_B3PEA2(111-290:291) Putative pseudouridylate synthase n=1 Tax=Cellvibrio japonicus Ueda107 RepID=B3PEA2_CELJU  E=5e-27 s/c=0.68 id=31% cov=68%
---------------KPHGLLAQGSQWGDHCSL--LRWVEVVRQRECFLVHRLDADAAGLILIAHDAQAAAALSQLFQGRSLRKHYQAWVSGELQATGLRLEQPL---------------DGKDALTWV---------NTAVIDQPNNRSLVDVRIETGRKHQIRRHLAAIGHPIMGDKLYGQANQ----------QPLQLLAWQLGFECPLLKRPITISLPEPLKFR--------------------------------
>UniRef50_C3JBT0(88-322:330) Ribosomal large subunit pseudouridine synthase family protein n=2 Tax=Bacteria RepID=C3JBT0_9PORP  E=6e-27 s/c=0.52 id=22% cov=90%
-VKVLWQDDWFILVQKEPGIPTIASKPGDRHTVyrIVADHYKSGDArEKIFLLNRLDRDTRGLILFARDREVQQEILDNWEKYILSQTFSALVEGVVPEEKGEFAPPPKPKKTVGDKDTKKKV----------VVSRRSRATYLVEERGQWRTLLRISLL-GRYNGIRSQLNEKKYPLVGESK----------GVIKGAPSIALSQQELVLLHPITKEKLRFESPIPSFFYKLLRR-----RLTTSERKIIEKRTESENDLS-
>UniRef50_Q0F2T6(92-290:291) Pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F2T6_9PROT  E=1e-26 s/c=0.61 id=29% cov=75%
----------LYLIHKKSGqyaqEALHRSRGTLPDELARHLELTPAQASELRPVHRLDRDTSGLMLFSASAAMLQHLQAHW-HDAVEKRYLAVVSPAPDWDD-QRIRLAIDRNRDAHGRYHLSPDGRACDSEAHVVERRD-----------NRALVELVPHTGRSHQLRVHLSALGCPILGDSRYGGKPH----------PRLMLHAVSLCIRPPALPETKQWNQPPEENWQ--------------------------------
>UniRef50_C4LG57(108-354:364) Pseudouridine synthase n=1 Tax=Corynebacterium kroppenstedtii DSM 44385 RepID=C4LG57_CORK4  E=4e-26 s/c=0.49 id=29% cov=82%
----------ILVVDKPPFLATMPRGRHITETATV-RLRRATGNDNLVPAHRLDRPTSGLLLFTTHPRYRGPYQTLFARRQVRKTYqaiapyhpvlaestdraeiehVAIDSGTISLEDDGIHVHQRMEKTHGFIQARLEPGKPNAETVIssirmltdddeRALREGYHNWFGDPLCDTRYALYTMHPLSGKTHQLRMCLNSLGVPIVGDQVYPRILPEAIDAhqhvDEAWHQPLCLRSTQLSWTDPNLHRPITVTAP--------------------------------------
>UniRef50_Q21JF5(19-174:209) Pseudouridine synthase n=1 Tax=Saccharophagus degradans 2-40 RepID=Q21JF5_SACD2  E=7e-26 s/c=0.77 id=34% cov=53%
------------------------------------------------PAHRLDKPTSGLCIFAKSSGAAAQFGQLFERKLVTKYYLAITSKKPAKKQGAIIGDMVKTRNGSWKLTAAKTN--PAITHF-----------FSFALASGMRLILLKPSTGKTHQLRVALKALGAAIIGDERYGGE----------PSDRLYLHAYQLEF----------------------------------------------------
>UniRef50_B8BXJ8(103-283:383) Putative uncharacterized protein (Fragment) n=1 Tax=Thalassiosira pseudonana RepID=B8BXJ8_THAPS  E=2e-25 s/c=0.65 id=30% cov=62%
---ILY------CINKPASVPVYPSGPYYSNSLLMMVEAQEGLPPKsLVPCHRIDRATSGVLLCTIDSKVSRAVQGRMASRNevgtqhpIKKLYLARVQGKFP-----DPSSSVPVGAASMMHRSVSRDGKQAISRFRLLSY---------DAATDQSLVSCCPITGRGHQLRVHLQFIGLPIHNDVEYGG-----------------------------------------------------------------------------
>UniRef50_D0N321(279-458:556) RNA pseudouridylate synthase, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0N321_PHYIN  E=2e-25 s/c=0.66 id=27% cov=59%
-VRVVYEDDDLIVVSKPPSMPTHPCGAYRHNSLHTILQATRPDLPQLNIVHRLDRLTS-------------------ADRQASKTYLARVRGRFPDVLSSEVQDKLVTQakeicpasiitfpeegavliscplrclSARDGVWECHEEGKPSETLVRLVRTDKC-----------TSLVKCKPVTGRTHQIRLHLQLIGFPIANDPCYGG-----------------------------------------------------------------------------
>UniRef50_UPI0000E0E896(2-204:240) 23S rRNA pseudouridylate synthase n=1 Tax=Glaciecola sp. HTCC2999 RepID=UPI0000E0E896  E=4e-25 s/c=0.58 id=24% cov=76%
---VLYDHSDFFIIAKPQGVTMHEASNGLPAVLplfkaaLANMAYPEAQYAHLHLVHRLDDHTSGCLIIAKHAVAAERFRELFSQQRIQKYYVALSHAKGKRKAGWVKGDMVNKRKGQWVLTKSVE--RPAISYF-----------FRQGLGNGLYLFWVKPFSGKTHQVRVALKSNGSGILGDPQYS----------SEPAQRMYLHAFALDFI--YDDEPIQIHCPVD------------------------------------
>UniRef50_B3PLS7(81-256:277) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Mycoplasma arthritidis 158L3-1 RepID=B3PLS7_MYCA5  E=7e-25 s/c=0.66 id=23% cov=68%
-FKVIFEDKNLLIVDKAINIAMHSEENSLDDQILKYLNYRLTSSFRPASIGRIDKKTSGLVVYAKNYAALVEFEKQQKY--FDKVYQFVSDFNEDKLDITVN-LKKDIGN--EKMIVDPKFGVKARTIFWVDGKHKF----------------AQILTGKTHQIRATLSYLKYPILGDSKYGGKR----------AKRLFLHSYSITF----------------------------------------------------
>UniRef50_UPI000186EBC6(26-185:227) Ribosomal large subunit pseudouridine synthase A, putative n=1 Tax=Pediculus humanus corporis RepID=UPI000186EBC6  E=1e-24 s/c=0.72 id=34% cov=56%
--------------------------------------------------HRLDYSTSGVMCVALSKKSCAAASIAFQEKTTKKYYLALLRGHVsKREIELNAPIGETIKKGLKIMSSEVKGALPACSRLLVLER-------GIYDSYPATKVLLRPLTGRRHQLRVHCNIIGHTIIGDYTYSQKKDVSP-------PRMFLHSIRLIIP---------------------------------------------------
>UniRef50_Q4DB45(8-333:378) Putative uncharacterized protein n=4 Tax=Trypanosoma RepID=Q4DB45_TRYCR  E=4e-24 s/c=0.35 id=30% cov=83%
-FSVIYGNEELVVVNKPHDVPmdgeacpvtvekwawaylakggcadnSAGGGVEKEEDTTRTAGRGRGEKKMVKFVHQLDYATSGVLCVAFSREMAARLAHCFEMRTTRKAYLAVLLGMMPTTSAMQKKLDTDtgvdflrgspyashvrrismddvpgvcfirkcvieasgheegenadccatllevnlpvgydtTDHEGFRMTVNGRDARGSVTYLSVLQRGHMTHPTSGC-SVPVTKVALFPRTGRRHQLRVHCHAIGFPILGDVTYARIPTPRVASKVTGAeevatvgaaesinapneidaieawQRMMLHAWRLSF--PVSMEPLR------------------------------------------
>UniRef50_D2VX88(13-249:272) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VX88_NAEGR   E=4e-24 s/c=0.48 id=25% cov=79%
-IPIIFKSRDVLVIDKPNDLHIDGDyeltvekliNNYYPEMENPLEEIQHKPGhtpsrRKLKFCHQLDYATSGILCLAFTRESCAKITYPFQQRTAQKQYLAVLRGHvLINDFEILTFIGEDPSDERKFRMRNFYLGREKTllselnTEEEIQEAKKSRESltfgsvlcrgfyHKDNDTIPVTKVLLRPKTGRRHQLRLHTQLLGFPILGDATYSLLGRDG----EEGVHRMMLHAWNLTLP---------------------------------------------------
>UniRef50_A4S879(47-255:359) Predicted protein n=1 Tax=Ostreococcus lucimarinus CCE9901 RepID=A4S879_OSTLU  E=5e-24 s/c=0.54 id=29% cov=66%
--EIVFECEktGLVVVEKPAGVPVLagaaPGWQGYGNLAALTSALRRRRAAkddaadetrrtkraratgdagKVWAVNRIDAPVSGIWLAATSPKLAAKANVWMSKTSLGKTYLALVRGAqIECGVRIDSPLAKDKESSL--AVVSEKDGKPCATRVVVLQRRE---------SEDVALVACRLEShGRYHQIRAHLSSIGHPIVFDSAYGD-----------------------------------------------------------------------------
>UniRef50_C1FHP0(253-672:730) rRNA/tRNA pseudouridine synthase n=1 Tax=Micromonas sp. RCC299 RepID=C1FHP0_9CHLO  E=8e-24 s/c=0.27 id=31% cov=90%
-LHVVYEDEWLMAVSKPAGVMTYPAHRLRGESVVSRAVHHLSVSAarrrgrlpyssedlpeesgvgtpvgtpggsfagawtssqvEPIAVHRLDLETSGVLLLAKDKRVASELQAKFEARGVRKTYLAVCAvledaeahkatatrrvdfeadvdtdvdsdadmdadvyadtdgdelGVFDESDldddddddayedpddeldeldepgvvrVVNAAIGDPEPGTRRSAAADDggrcvravtPDGKPARTEYQCLSSrlgvptqVTMPDGVTRRTVVGTALVLARPLTGRTHQVRLHLAHAGFPIVGDGLYGvdyasvaasigafrlsgggitreereaaarrrllfassspssssavsprddasaggeSPGSESPDDVPSPCARLALHAWNVDVLHPRALVPLRLCVDMPRDMTDLARALG-------------------------
>UniRef50_C5KHN4(113-290:296) Ribosomal pseudouridine synthase, putative n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5KHN4_9ALVE  E=8e-23 s/c=0.61 id=27% cov=65%
---IVFirEDSArgIVAVHKPAGLPTHSGGKYMRTSLVHILARAFNLST-IRPINRLDRETSGVVLLAADASVHERLKD-----------RSLLSKVPALCRTPIAVDRHVPNQPLMSRVVED--------------STNSTLCTTLFRNLGNGVVACRPVTGKTHQIRVHLSHLGFPIQGDTLYGGR--------STPEGRLRLHAH--------------------------------------------------------
>UniRef50_C1DA62(1-215:236) Pseudouridine synthase n=1 Tax=Laribacter hongkongensis HLHK9 RepID=C1DA62_LARHH  E=1e-22 s/c=0.51 id=27% cov=72%
MYRLVDEQAAFLVIDKAPGTHVH---RDGEATGLMDRLRDDTGCDTLHLVHRLDAMTSGLLLVARSADAAAALGQALAARQVEKFYLALSDRSPRKKQGWVIGDMERSRRASWKLLPTRQD--PAVTQF-----------FSAAAGDGRRLFLLRPRTGRTHQLRVALKSLGAPIWGDPLYHPQEPGREAP-----DRGYLHSYGIGF----------------------------------------------------
>UniRef50_B3S5A5(35-264:267) Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens RepID=B3S5A5_TRIAD  E=1e-22 s/c=0.47 id=27% cov=77%
---------NVIAINKPYGIASHDNPGIGYNCHSIYRELNlDDDSQPVYLSHVLDRNCTGILIGSK----------------------AITVGIPKaIKGTIDIPIVEDKTLKRVKLKMQDEGAskqeiaykyggrvRLASTNYKVLSKSEI----------GCALIEFETKTYYKKQIRVHAAdALGCPVLGDHQYSSKKIGHNQVVSPKIGQalnliggntntlkMHLHLRKVTIsKWPASGKVINlaIVASPSYEFMQTLEMLQLKSP---------------------
>UniRef50_B5JQR9(28-262:270) RNA pseudouridine synthase family n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JQR9_9BACT  E=9e-21 s/c=0.44 id=25% cov=82%
-------DEGLFAINKPAGLASfqHEWSLGKPDISMALRRellnekpqLKKLGIEGLYRAYNLDSELSGALVFAKNEEFEKILKNAVGSSQLVFRFHLLVKaETEDREFVCDLPLM--NHHQAKRMIVSHRSGKKCETRFRFLRGF-----------GQYQLWEAETTSLRVHQVRVHAAERGLNIVGEDFYSDGEEiylsrikrdymSGRGREKPLYGSLCVHLVEVEFRIPDLKLE-SILAPLPSRFETLLKRL--------------------------
>UniRef50_Q5CTM4(125-345:481) Yd1036cp-like RluD, S4+type 1 pseudouridine synthase n=2 Tax=Cryptosporidium RepID=Q5CTM4_CRYPV  E=9e-20 s/c=0.45 id=24% cov=70%
-VKILYDSSTLLAVFKPCGIPCHPQGRFNKLSLTKLIQSEylsklNTNSTYIHPINRLDRVTSGLVLLSKDSSTTKNLSS--KVQFAHKYYLAMInestsnfishisqssiegvsirelsldesHGITSHVIKCEIGLKTLKDREGEsliTRIDSSENSKYSLTYFFPLIScldINEAKKQKINETDKYSILLCKPITGRTHQIRAHLKYIGFPIVRDILYSDK----------------------------------------------------------------------------
>UniRef50_B7FTR4(233-434:497) Predicted protein n=2 Tax=Bacillariophyta RepID=B7FTR4_PHATR   E=3e-19 s/c=0.49 id=19% cov=68%
----LYEDTTFIVVDKPPLLPTQPDSSNYVECCpgCVQDNLgpftdiQGNEVVRPLLCHRVDSCVGGCVVLSKDGNGQKVFQEMQRERKLRKLYLAVTTQPVPlgmHLHWMWAPQSARGKSGGPPCQLVSHAPPESrrkarqfwnrcvleVVKCEPIKIGKEDSHTYDPAGKVHYQSTIRLVTGRKHQVRAQLASLGAPIIRDSLY-------------------------------------------------------------------------------
>UniRef50_A2F8F2(1-123:173) RNA pseudouridylate synthase family protein n=1 Tax=Trichomonas vaginalis RepID=A2F8F2_TRIVA  E=4e-19 s/c=0.79 id=30% cov=42%
--------------------------------------------------------------MAKSDSAAKRFTEMLNNNKIEKTYIARVLGqFPPEKKIVDLPIIESAESRAKMVCK--EGGKPSQTEFELVTT-----------NGKESIVKCHPITGRTHQIRVHLASIGFPISNDVFYGG-----------------------------------------------------------------------------
>UniRef50_Q9SVS0(210-397:472) RNA pseudourine synthase 6, chloroplastic n=8 Tax=Embryophyta RepID=PUS6_ARATH  E=2e-18 s/c=0.51 id=19% cov=66%
--------DSYVILDKPAGTTVGGTTDNIEESCATFASRALDLPEPLKTTHQIDNCTEGCVVFARTKEYCSVFHTKIRNKEVKKLYRALAAAPLP---IGIISHYMRPKNMAPRLVAEDSIQGWHLCQLEVLECKKIPWPDAATEKKHdiedcgwtskefAYECTINLLTGKTHQIRAQLAACGAPLVGDSMY-------------------------------------------------------------------------------
>UniRef50_Q05FL2(4-198:204) Pseudouridine synthase n=1 Tax=Candidatus Carsonella ruddii PV RepID=Q05FL2_CARRP  E=4e-17 s/c=0.47 id=24% cov=60%
-FKINYFDNNIIVINKPIGIEV------KNLLNVNFIKLNDKI-PNFGILNRLDKYTSGLILVAKNFYFYFYFKKLIVKNLIKKNYISFVNKKIKKGFVNVDIFKKKKSSIIKNNKKS-------ITYYKIIKEKK-----------NFSFLNICIKTGRTHQIRLHMMHIEKKIFNDFYY-------------------------------------------------------------------------------
>UniRef50_UPI00004D58A9(3-263:264) RNA pseudouridylate synthase domain containing 3 n=1 Tax=Xenopus (Silurana) tropicalis RepID=UPI00004D58A9  E=4e-17 s/c=0.35 id=21% cov=82%
----------LVAINKPQGLSITGKEQEVSVSSLLADLQQHlGLGSDLHIVKAAPKESSGLVLLSTCHMTTKRLEDYYAlCRKAQKptaSYCAVMAGVPHPAEGEIKAALKLERIEDWQLVVPVTDPskgrlerreiKRTLTRYKVLDSAD-----------GCALVQLQPMSVFQAQLLVHSTLMFCRILGDHTYSARvgkvlGENIFVPMDIALPRtqvleenvlrrmhftqqqmhrmpLHLHFQQLMIPgeSPAEGDTF-LDAPPPPFFQRTLQLLG-------------------------
>UniRef50_C5DL01(7-189:234) KLTH0F08866p n=1 Tax=Lachancea thermotolerans CBS 6340 RepID=C5DL01_LACTC  E=5e-17 s/c=0.49 id=23% cov=64%
-INLVYEAKNYVIANKPPGVFCQPPDRNvwynaqYKEPPILLELLKSQastRAAEWRPVHRLDTNVTGGVLVAKNKNAAAMFSRHLKKggnhgYKLTRRYVALVEGN-----TAELPD----------TGVISENGR-----------------LSKFKKAGLHVLVLQLCTGKKHQIRQQLsQCLKLPILNDLKYGGRQITGAGRQ------IALHSA--------------------------------------------------------
>UniRef50_A6ET76(2-122:130) Ribosomal large subunit pseudouridine synthase D n=1 Tax=unidentified eubacterium SCB49 RepID=A6ET76_9BACT  E=5e-17 s/c=0.75 id=37% cov=35%
-----------------------------------------------------------------------------------------------------------------------PDSKQAILHYEVIKKLD-----------NYYLLSIDLETGRHHQIRSQLAAIKCPIKGDLKYGFDRSNKDGS-------IHLHARKITFTHPVKKEEMTILAPTPDE----------------------------------
>UniRef50_C1EHD0(184-468:481) RNA pseudouridylate synthase n=1 Tax=Micromonas sp. RCC299 RepID=C1EHD0_9CHLO  E=1e-16 s/c=0.31 id=24% cov=69%
---VVHEDDAILVVNKPHRLPSMAHESNGVEHCAGCLERSLGLSPStLRVTHRLDSSTSGVLVLGKTATAVREFNDSVAKtpgsKEIVKSYaalvyakHAVPLGLMTHWMYpgpfgPGAFHGRTLRRSRARLVRSSADGergddtggqgtgkRWKRCELRVVSCDRAtqsqvdtwrtlfdrelerarkpfdggaddplvsggDSPGGDSPGASVWAVRVELVTGRTHQVRAQLAAAGAPLLGDSLY-------------------------------------------------------------------------------
>UniRef50_Q1IJT7(65-250:680) Pseudouridine synthase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=Q1IJT7_ACIBL  E=5e-16 s/c=0.47 id=22% cov=62%
-----------VLLHKPKGYVT--TVSDPEGRETVMDLVK-GIPARLYPVGRLDYLSEGLLLLTNDGEMAAKLTHA--STHVPKKYLVKVSGEPTEEQIQELRNGVQlPPEQGHIHADPREGGRFGGEKRRSTAVKTAPCKIELTREGDNPWYEVTLNEGRNRQIRRMFDFIGHHV-------------------------------------------------------------------------------------
>UniRef50_UPI000194D267(27-193:270) PREDICTED: similar to RNA pseudouridylate synthase domain-containing protein 3 n=1 Tax=Taeniopygia guttata RepID=UPI000194D267  E=2e-15 s/c=0.51 id=26% cov=62%
---VVHREGALLALSKPPGLPILGRPGDLSlDSLLPALRRRLGLAAELHVVKAPAREYSGLVLLSSCYHTTKKLHQFFtsarRRGQYPATYRAVTVGVPAE--------VEGEVSTGLCWQQQGDRAMSTLTHYRVLST-----------TGGCALLQLQPRTAFPEQLQVHLTLLLCPALGDHKH-------------------------------------------------------------------------------
>UniRef50_P35159(62-202:244) Ribosomal large subunit pseudouridine synthase B n=200 Tax=Bacteria RepID=RLUB_BACSU  E=5e-15 s/c=0.59 id=26% cov=53%
-------------LYKPRGVIS--AAQDDKGRKVVTDFFKN-IPQRIYPIGRLDYDTSGLLLLTNDGEFANKLMH--PKYEIDKTYVAKVKGIPPKELLRKLERGIRL-----------EEGKTAPAKAKLLS---------LDKKKQTSIIQLTIHEGRNRQVRRMFEAIGHEVI------------------------------------------------------------------------------------
>UniRef50_Q4Q7A0(210-498:533) RNA pseudouridylate synthase-like protein n=3 Tax=Leishmania RepID=Q4Q7A0_LEIMA  E=5e-15 s/c=0.29 id=32% cov=49%
----------------------------------------------LFTVQRLDKETSGVVVLAKNSVSARTLASQleaqtkgcadavesrlrerghavalssdafdellrLKAQSVHKTYTAVLRGAAPEDHTfvvvnCMDCMAKHPTHsweaqhtqlKKLKMCCEPvkemlfshaaaalpqspkeqqtRWGRLAVTRIRVLASNK---------KLGLTCVQVELLTGRSHQIRLHCAAVGYPVLGDKLY-------------------------------------------------------------------------------
>UniRef50_UPI000194C6EE(182-262:479) PREDICTED: similar to RNA pseudouridylate synthase domain containing 2 n=1 Tax=Taeniopygia guttata RepID=UPI000194C6EE  E=2e-14 s/c=1.01 id=34% cov=31%
-IRILAEDEEVVVVDKPSSLPVHPCGRFRHNT-VIFILGKEHGLRELHTLHRLDRMTSGVLMFAKTAAVSKRIDEQVRQRQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9CKK7(51-200:241) Ribosomal large subunit pseudouridine synthase E n=61 Tax=Bacteria RepID=RLUE_PASMU  E=2e-14 s/c=0.55 id=23% cov=57%
----------VILFNKPYDVLTQFSDEEGRATLKAFI-----PIPHVYPAGRLDRDSEGLVLLTNNGEIQHRL--AVPKFNTEKTYFAQVEGIPQET---------DLAQLRQGVVLNDGKTLPAKVRLvpEPNWLWQRNPPIRERKQIPTSWLEIKIHEGRNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_Q6MIA3(44-184:265) Putative pseudouridylate synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MIA3_BDEBA  E=2e-14 s/c=0.58 id=20% cov=54%
------------ILNKPTGVLT--TMDDPHDRPTVAEYL-TELPVRVFPVGRLDWDSEGMLLLTNDGDFANKVMH--PKAEVTKTYLVKLNGKPEPFQL-----------EKLKKGVSIVGGKVSARHIEKIKK------TGDNKSEKYEWYKIVITEGKNRQIRQMFAKIGF---------------------------------------------------------------------------------------
>UniRef50_P72581(42-191:261) Uncharacterized RNA pseudouridine synthase slr0612 n=16 Tax=Bacteria RepID=Y612_SYNY3  E=3e-14 s/c=0.54 id=21% cov=58%
-----------IVFYKPYGVLCQFTDNSAHPRPTLKDYINL---PDLYPVGRLDQDSEGLLLLTSNGKLQHRLAHREFAH--QRTYFAQVEGSPTD---------EDLEPLRRGITFADYPTRPAIAKIITEPDFPPRNPPIRYRASiPTSWLSITLTEGRNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_Q2K4S3(131-266:312) Pseudouridine synthase n=10 Tax=Rhizobiaceae RepID=Q2K4S3_RHIEC   E=5e-14 s/c=0.59 id=22% cov=52%
-----------LMLNKPRGLVT--TRQDPEGRPTVYDCLKNFDIPHLSPVGRLDKASEGLLLFTNDTEFAQTLLDPL--THVTKTYHVQIDRLMDDEEIAAMTSGIRHDG----------------------ELLTAAATRRLRQGDRNSWIEVELDEGRNRQIRRMLEALG----------------------------------------------------------------------------------------
>UniRef50_C4V2S0(65-202:290) Pseudouridine synthase n=1 Tax=Selenomonas flueggei ATCC 43531 RepID=C4V2S0_9FIRM  E=5e-14 s/c=0.58 id=25% cov=52%
-----------ILLHKPRGCLS--TAYDDRGRRTVLDLL-PHFPARLYPVGRLDADTEGLLIITNDGAMTQGLLH--PRFEIDKVYRAEVTGNVTEDGLTALRNGILLD-----------DGRTAPARLRVLHR-----------EGERTVVETIIHEGRKRQVRRMFAAIGC---------------------------------------------------------------------------------------
>UniRef50_Q3AVD5(65-204:247) Pseudouridine synthase n=3 Tax=Cyanobacteria RepID=Q3AVD5_SYNS9   E=8e-14 s/c=0.57 id=28% cov=54%
----------VFLLNKPVGVIC--SCRDPQGRATVLDCLPHQERSGLHPVGRLDADSRGALLLTDQGELTLRLTHPRYNHA--KTYRVLVRGIPSSQALRRWRDGLLLDGRLTRPARVH----------------------CLRSRGASSLLEVELKEGRNRQIRRVAELLGHPVI------------------------------------------------------------------------------------
>UniRef50_A2RP35(139-324:328) Pseudouridine synthase n=172 Tax=Firmicutes RepID=A2RP35_LACLM   E=1e-13 s/c=0.43 id=27% cov=35%
---ILdYQEYYYYLLNKPQGVVS-ATKDNVFKT-VVQLLSEKDFRKDIFPVGRLDKNTEGLLILTNDGALGHDLTQ--PKKHVEKEYFARIDGKVTDE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2T6J8(2-152:189) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=B2T6J8_BURPP   E=1e-13 s/c=0.52 id=23% cov=58%
---------HLLALNKPFGTICQFSP--HETRASLADWVK---VPDVYPAGRLDSDSEGLLLLTDDGALQARIAE--PRHKLVKRYWAQVEGAVDAATLKKLARGVDLGDYVTRPCRAEYVEP-------TDALWTRTPPIRFRAAIPTTWIELSITEGKNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_Q87QY8(63-211:238) Ribosomal large subunit pseudouridine synthase E n=244 Tax=Bacteria RepID=RLUE_VIBPA  E=2e-13 s/c=0.53 id=24% cov=57%
----------VIIFNKPYDTLSQFTDGDGRKTLADYIPVKD-----VYAAGRLDRDSEGLMVLTNDGILQAKLTQ--PKSKSPKTYWVQVDGAPQEQ---------DLEKLRKGVELKDGMTLPA--KVEVIDAptiWERNPPVRFRANIPTTWLAITIIEGRNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_B0W634(12-287:493) Ribosomal pseudouridine synthase n=1 Tax=Culex quinquefasciatus RepID=B0W634_CULQU  E=2e-13 s/c=0.28 id=30% cov=57%
---------------------VHPCGRYRHNT-VVFILAKEYNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEHQIRNRQVQKEYICRVEGEFPESspvsnsanhpaaapaqqqrehtssrssrgkrrrssprtallVVAARHQAKHEDEERERtlggdpsphrpvkkggslnhhtrtaensltsnalprskrclvagggtaddellgmgsntldgiieckepievvsykigVCKVSPKGKECTTTFQKLGY-----------NGSSSVVLCKPLTGRMHQIRVHLQYLGYPVVNDPLY-------------------------------------------------------------------------------
>UniRef50_Q1J642(57-200:244) Pseudouridine synthase n=51 Tax=Streptococcus RepID=Q1J642_STRPF   E=8e-13 s/c=0.53 id=28% cov=56%
----VYESFVYYLLNKPSGYVS--ATQDRQQATVMELLDDTARQKTVFPVGRLDKDTRGLLLLTNNGQLAHDLLS--PKKHVTKEYLAKVAGIMTEA---------DKDYFARGISLKDHQCLPA--HLEVLAS---------DLQQQTSLVKITIQEGKFHQVKRMVAACG----------------------------------------------------------------------------------------
>UniRef50_O96270(119-301:338) Pseudouridine synthase, putative n=2 Tax=Plasmodium RepID=O96270_PLAF7  E=1e-12 s/c=0.41 id=20% cov=62%
-----------IVLHKPKGLLC--TSNDEKNRKSIYTLFPEEMLQkyRLVTVGRLDRNTSGVLLLTNDYAWVNKLTHPKYQRI--RTYRVHIEGPVKMNALKELARGIYLEEDEKTQPKKIYNYKESReksniddkkkkkmskmkkkTNPAFIEILREEKIKIKEDTKKITVLNISIKEGRNRQIRKMFQQINQPVI------------------------------------------------------------------------------------
>UniRef50_Q9F855(66-214:241) Ribosomal large subunit pseudouridine synthase E n=107 Tax=Bacteria RepID=RLUE_VIBCH  E=2e-12 s/c=0.50 id=23% cov=58%
----------VILFNKPYDTLSQFTDGDGRKTLADYIPIKD-----VYAAGRLDRDSEGLLILTNDGILQARLTQ--PQSKAPKTYWVQVEGSPQESDLEALRHGVTLKDGPTLPAKVDIMPEPTL--------WPRNPPVRFRAAIPTTWLAITLMEGRNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_D0IWI1(43-192:223) Pseudouridine synthase n=2 Tax=Comamonas testosteroni RepID=D0IWI1_COMTE  E=2e-12 s/c=0.50 id=25% cov=56%
----------LLCFHKPYGVLSQFTPEGK------WQGLKDWIDvPGVYVAGRLDADSEGLLLLTNDGQLQARIAD--PRHKMEKTYWVQVEGIPDEAALQ-----------RLREGVELSDGKTLPAKARLIEPqplmWPRNPPIRVRQNIPDCWIELIIREGRNRQVRRMTAAVGHP--------------------------------------------------------------------------------------
>UniRef50_B8LDC7(264-595:686) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LDC7_THAPS  E=3e-12 s/c=0.23 id=22% cov=70%
---IVARDDDagYLIINKPPSTPVHARVDNlvenvassvgrmfwmeRRESILNQLHddvdrageyddgqatkrkRRKQKIEQLVYVatpQRLDQNTSGLLVVASKKSFASYFAKLLRTKTsgqlvtcriesksdanaeekyyrssscgVHKTYRCLVCVMPSKSSSADDTSIKSMKSEVERLRKysrertvvrhflepsirapkaffstvpkdvyNPESWAECLLRITNVSDICTVVGNKPSDELAVSLwgesgkpdecvavveLEVELLTGRTHQIRGQLAAEGFPLVGDAQYGG-----------------------------------------------------------------------------
>UniRef50_Q6CQC4(42-228:299) Pseudouridylate synthase PUS5 n=1 Tax=Kluyveromyces lactis RepID=PUS5_KLULA  E=3e-12 s/c=0.40 id=23% cov=58%
----LWRDKHHVIFNKPPLALSQlPDKRTWYNThdydpPVLLDIVQSSSGsilkdgtyePSYYPIHRIDTPVSGGIVYAVNKQSAQQFSRNLRYGgnkgfSLTRKYVA-KVGKSKTANECKEGLIKWNG---------------AITYFQRVDNEH---------------LILQLVTGKKHQIRKLTQQvLDSPIYNDLKYGGKK---------------------------------------------------------------------------
>UniRef50_C6MZI4(55-203:240) Pseudouridine synthase n=1 Tax=Legionella drancourtii LLAP12 RepID=C6MZI4_9GAMM  E=3e-12 s/c=0.50 id=20% cov=57%
----------LILFNKPFAVVCQFTGEKHEHTLA-----EFIDKPDFYAAGRLDKNSEGLLLLTNDGALQHQLTH--PKFNKKKYYWVQVEGIPT---------AADLEPLKKGLVLKDITFLPA--EVRCIEEpalWPRTPPVRFRQSIPTSWLEIILREGKNHQVRRMTAAMGFP--------------------------------------------------------------------------------------
>UniRef50_C9LMF3(76-235:277) Ribosomal small subunit pseudouridine synthase A n=1 Tax=Dialister invisus DSM 15470 RepID=C9LMF3_9FIRM  E=5e-12 s/c=0.46 id=22% cov=58%
-------------LNKPAGVIT---ATEDRYQKTVLDFFGERRRKDLSPVGRLDKDTVGLLLVTNDGGFHHRLLS--PKKHIDKEYYARIDGRVDEADREKFEKGIYVDEIFTALP-----AKLMIDGYRenALESDFMDLANSRAPKsaleNGVSEIRVVVQEGKFHQIKRMFHALG----------------------------------------------------------------------------------------
>UniRef50_D0ND20(111-263:263) Putative uncharacterized protein n=1 Tax=Phytophthora infestans T30-4 RepID=D0ND20_PHYIN  E=1e-11 s/c=0.48 id=28% cov=36%
-LRVVYECSILALVVKPVGIHVKGRGKRTVEQALPLLLRKQHVDagdfelPLPHAVHRLDYRVGGLLLVAKTRKMEVKLSAQFERHSVAKQYRAILVGNV----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1ZI67(219-356:391) Pseudouridine synthase n=1 Tax=Microscilla marina ATCC 23134 RepID=A1ZI67_9SPHI  E=1e-11 s/c=0.53 id=28% cov=28%
-----------VLLNKPKDFIT--TTNDPQDRKTVMDLIKNSCDERIYPVGRLDRNTTGLLLFTNDGEVAKKLSH--PSHDVKKVY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1CFA0(66-202:253) Pseudouridine synthase n=1 Tax=Thermobaculum terrenum ATCC BAA-798 RepID=D1CFA0_THET1  E=1e-11 s/c=0.53 id=22% cov=33%
-----------ILLNKPAGVLS--TAKDERGRKTVIDLL--GQSNRVYPVGRLDKDSEGLMLLTNDGELAQRITH--PRYGVHKQYMVEVEGYFSDRSLQDL--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4D992(536-663:682) Putative uncharacterized protein n=1 Tax=Trypanosoma cruzi RepID=Q4D992_TRYCR  E=1e-10 s/c=0.54 id=34% cov=29%
-----------------------------------------------------------------------------------------------------------------------------------------------------SVVECLLLTGRTHQVRVHLASLGHPIRGDKKYIRLAADSPSIPLRTDLRdeeeedeeeeeeeskgylsshgIFLHAWRYTLRYAAGEAPEVLEAPPP------------------------------------
>UniRef50_Q4Z2R8(124-298:318) Pseudouridine synthetase, putative n=3 Tax=Plasmodium (Vinckeia) RepID=Q4Z2R8_PLABE  E=1e-10 s/c=0.40 id=21% cov=60%
-----------IVMHKPKGLIC--TNQDEKDRKSIFSIFPDDLLQKYRIvsVGRLDRNTSGVLLFTNEYTWVNKLTH--PKYERVRKYMIHIEGPVRMDALKMLANGVYLKDE-DNNKKKKKKTQPA-----FIEVLREENVKIQNQIKKITVLNISIKEGRNRQIRKMFQQINQPIV------------------------------------------------------------------------------------
>UniRef50_A3M7K0(3-152:262) Pseudouridine synthase n=13 Tax=Acinetobacter RepID=A3M7K0_ACIBT   E=1e-10 s/c=0.46 id=19% cov=58%
----------IVILNKPYDVLSQFRKDEAHMTVSDFV-----DDPTLRIAGRLDMDSEGLVFLTDHGGLNQFITN--PANKKYKTYLVQVDGDVTEEALEQLRKGVELNDGMTLPAK-------AIKVSEPEWLWDRDPPVRYRASIPTSWIEISICEGRNRQVRRMTSAVGFP--------------------------------------------------------------------------------------
>UniRef50_Q01Z61(75-208:264) Pseudouridine synthase n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q01Z61_SOLUE  E=2e-10 s/c=0.51 id=25% cov=27%
-----------ILLYKPKGYLT--TYRDPEGRPTVYALLGD-VGKWLSPVGRLDLDTSGLLVLTNDNDFAERITN--PEHKVPKTY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3ZQL4(78-215:517) Pseudouridine synthase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A3ZQL4_9PLAN  E=4e-10 s/c=0.49 id=23% cov=52%
-------------LNKPPGVLS--TNFDPAGRTRVIDMVPQ--DVRLFTIGRLDRASEGLIVVTNDGELANRLAH--PRYEIEKTYRVEVAGHPEPDAITFVRRGVHLAEGFVQPVSVVMKRK----------------------NKQSTTLEVILDEGKNREIRRLMAKIGHKVL------------------------------------------------------------------------------------
>UniRef50_C1ZE67(94-235:554) Pseudouridine synthase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZE67_PLALI  E=7e-10 s/c=0.47 id=28% cov=31%
--------------HKPAGVLC--TNSDPAGRTRVIDCFPPNVG-RLFTVGRLDDGTEGLLIVTNDGDLAERLTH--PKFGIPRIYRAVVAGNPSTEAI-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1U6Q2(61-193:231) Pseudouridine synthase n=4 Tax=Gammaproteobacteria RepID=A1U6Q2_MARAV  E=1e-09 s/c=0.50 id=22% cov=50%
--------------HKPAGVLSATT---DSSQPTALDLLPRGLASRVHIAGRLDKDTTGLLLLTSDGQWSHAVTS--PRRECRKSYRVWLAEAIPEQACRAL-------EKGVMLNGETTETRPAEVRV-----------------HNNQLIDLTIGEGRYHQVKRMLAAVG----------------------------------------------------------------------------------------
>UniRef50_A5EVQ2(73-216:266) Pseudouridine synthase n=1 Tax=Dichelobacter nodosus VCS1703A RepID=A5EVQ2_DICNV  E=1e-09 s/c=0.46 id=26% cov=32%
----------ILMYHKPAGEIC--TRKDPEGRVSVFQHLPKISHGRWVAIGRLDLNTSGLLLFTNDGALANQLMH--PSAEIEREYWVRVAGEVTEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1N350(62-203:230) Predicted protein (Fragment) n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N350_9CHLO  E=2e-09 s/c=0.46 id=19% cov=53%
---------------KPRGVTCTTDARDRTNIVDAV----NYPDARLFPVGRLDKDSTGLILLTSDGRLPNA--ALRSGRKRDKKYLVVVDAVVRPEDVRMLRDGVVISTPVQRDRVD-----------RVLTARTLPCEIDVVGART---LEITLREGRNRQIRRMLDAVGY---------------------------------------------------------------------------------------
>UniRef50_Q6BNX8(30-326:339) Pseudouridylate synthase PUS5 n=2 Tax=Debaryomyces hansenii RepID=PUS5_DEBHA  E=2e-09 s/c=0.22 id=21% cov=87%
-----------LIINKPSGIQCNGTKSHSNYLLpQLYKQLKAHFsannpnyklnPDQYKVVHRLDKYVSGGLIIARGKNAnafRKSFSNQNTNLSVKRKYIGLVPipntvsfkqhlhefGDLKVQHENEVRYLNRPESVTDKkglifkddsltegiinfdivaLPKDDRRNKNtgelvtysALTKFKILHSMSQVPTNEQisrfpklYKNKTIYPIIIELETGRKNQIRDHiLQAFKVSLLNDDKFIDFKMVQKsntaniNSEVYNSNQIGLHSAYISIsKSSFANEYV---IPIPEG-----DEYLWKGFLDEN-----------------
>UniRef50_B8BYZ7(69-204:571) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BYZ7_THAPS  E=4e-09 s/c=0.47 id=30% cov=34%
---VVYQDDNYLVINKPPDLrmdgpylaSVHklllylfppPSLRGPSqeggggdvegdstdiNTTSNLQLDHRHhtqllqaiaplskhsslRDDPFRIVHQLDYATSGVLLYAKNRKAAGKACISFQERKTDKQYVAIV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6BG46(24-188:216) Putative uncharacterized protein n=2 Tax=Clostridiales RepID=A6BG46_9FIRM  E=8e-09 s/c=0.38 id=20% cov=61%
--------------HKPFGCVT---ARRDDRYPTVMDYFEELQNDRLSPVGRLDRETTGLLLITDDGIFNQKLTH--PSYHKEKTYEFTLLGDLTPELVHKLEtgvILKGADTLTAPAKITVTGHAVMSDILSTLPEEIQKDIHKNRPDHPITYGIITISEGKKRQIRRMMKSVHCCVI------------------------------------------------------------------------------------
>UniRef50_A5CX60(67-194:241) Pseudouridine synthase n=1 Tax=Candidatus Vesicomyosocius okutanii HA RepID=A5CX60_VESOH  E=1e-08 s/c=0.49 id=25% cov=23%
----------VIILNKQAGVIC--SNRDDKGRKSVYSLLPK--ESRWIMVGRLDLNTSGLLLVTNNGDLANKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3DRY9(81-218:256) Pseudouridine synthase n=7 Tax=Bifidobacterium RepID=B3DRY9_BIFLD   E=1e-08 s/c=0.45 id=19% cov=53%
-----------LALNKPRKVLS--AMDDPKGRYTLRDIVGDKY-ERIFHMGRLDYDSEGLILMTNDGELSQHVMH--PKYEVEKTYVATLEGKISGTVC----------RRLVTTGVQLDDGWIKLDHCAIIDS-----------SRDHTMVKVVLHSGKNRIVRRIFGSIGFPV-------------------------------------------------------------------------------------
>UniRef50_Q8ZGM2(62-198:235) Ribosomal small subunit pseudouridine synthase A n=134 Tax=Gammaproteobacteria RepID=RSUA_YERPE  E=1e-08 s/c=0.46 id=22% cov=50%
-------------LNKPQGYVC---STEDPDHPTVLYFLDEPVAYKLHAAGRLDIDTTGLVLMTDDGQWSHRVTS--PRHHCEKTYLVTLEHPLSDDTAQQFADGVQLYNEK------------SLTKPAQLDVIEPQR------------VRLTISEGRYHQVKRMFAAVG----------------------------------------------------------------------------------------
>UniRef50_Q5SLZ5(65-197:243) Pseudouridine synthase n=4 Tax=Bacteria RepID=Q5SLZ5_THET8   E=1e-08 s/c=0.47 id=22% cov=50%
-----------VLLHKPPGFVTSRTEG-----PSVYALLQGFPTRDLSPVGRLDKDAEGLLLFTTDGLLLHRLTH--PRHKVAKRYLVHLERPVGP---------KDQEAFREGILLDGKKTLPAE----------------LTPLEDPTWAEVVLKEGRFHQIKRMFRARG----------------------------------------------------------------------------------------
>UniRef50_UPI000187DE6E(79-171:175) hypothetical protein MPER_11162 n=1 Tax=Moniliophthora perniciosa FA553 RepID=UPI000187DE6E  E=3e-08 s/c=0.66 id=21% cov=33%
-VKVLLEDKerEFLIVDKPGSIPVHACGRYHRNTLVAILNHDFGYEK----VYRL-------MIIPTSAICARKVTEEFVSGTVRKEYVARCIGKFPE--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9KC52(61-190:240) Pseudouridine synthase n=1 Tax=Thermotoga neapolitana DSM 4359 RepID=B9KC52_THENN  E=4e-08 s/c=0.47 id=26% cov=31%
-----------ILFYKPAGYVT--STRDPH-SETIMEFLPDIKG--IFPVGRLDKDAEGLLLVTNDGEFAHRVIS--PRWKVEKEYVVKVEGEITED-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5INL2(16-167:243) Ribosomal large subunit pseudouridine synthase E n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5INL2_9CHRO  E=6e-08 s/c=0.40 id=24% cov=57%
-----------LLFHKPYGVLSQFTP----EPGSRWRCLADFIAvPGVYAAGRLDADSEGLLLLTANGRLQQRLTDPAFGHW--RTYWVQVEGEAGQRPEA-------LQQLRQGVVIQGRLTRPAL--VRCLSDPKLPErdpPIRQRATIPVSWLELQLQEGRNRQVRRMTARVGLP--------------------------------------------------------------------------------------
>UniRef50_Q6F9V5(61-200:239) Pseudouridine synthase n=17 Tax=Acinetobacter RepID=Q6F9V5_ACIAD   E=6e-08 s/c=0.43 id=26% cov=22%
----VYREKVYIILNKPKGFEC---SHQPHHHQSVFSLLPDLLIQRnIAAVGRLDQDTTGLLLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0F269(104-242:289) Pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F269_9PROT  E=1e-07 s/c=0.43 id=23% cov=52%
--------------NKPKGQLC--SRLDKKKRPLIYDFI--DVAPNVQSIGRLDMDTEGLLMLTDDGALTRALTH--PAAKVPREYRARVAGIVELETLAKLRRGGMDIGRG--------------------DTSDAWEVTVDSESAGHTWLNIIILRGRWREVRRTLEECGHPV-------------------------------------------------------------------------------------
>UniRef50_C9RMB6(92-260:286) Pseudouridine synthase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RMB6_FIBSS  E=2e-07 s/c=0.35 id=23% cov=56%
--------------NKPRGYVT--TASDEKGRATVMDLFREQYAkmfpgkpvPHISPVGRLDAASEGLLLFTNDTQWADALLKTKDERRKtrddkcveresrgpihTKIYRVQVNGHPTA---EELSQMEAGFNVPPRVFGEPEEFMHAVS------------AKLYSAGEKNCWLEITLDEGKNREIRRMLAKLGYEVL------------------------------------------------------------------------------------
>UniRef50_A7HJ21(67-223:265) Pseudouridine synthase n=3 Tax=Thermotogaceae RepID=A7HJ21_FERNB   E=2e-07 s/c=0.37 id=22% cov=55%
------EDDNVLvdgkilkpnqfeyyVLHKPKDYVT--TLFDPKQKKTIGELIK-HIKTPLKPAGRLDKDATGVLILTNDGELIDILTNA--KYRVKKEYIVKVKSVVSAEEL-----------VKLKKGIYDKGEFLKLEHFKIIE-----------KSSEYSIVRVELIKGKKHEIKRLFSSIGHNVL------------------------------------------------------------------------------------
>UniRef50_A7HC79(70-208:354) Pseudouridine synthase n=1 Tax=Anaeromyxobacter sp. Fw109-5 RepID=A7HC79_ANADF  E=2e-07 s/c=0.42 id=26% cov=31%
-------------LYKPPGCVT--TASDPEGRPTALEYLR-GVKERVFSVGRLDFDAEGAVLFTDDGELANRLAHPRYGHR--RTYLVKVRGEPPPAA------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8FRI1(38-187:218) Pseudouridine synthase n=17 Tax=Bacteria RepID=A8FRI1_SHESH   E=4e-07 s/c=0.38 id=22% cov=57%
---------------KPYGYLSQFVPERRKSKKLLAELALFPAGT--MAIGRLDHDSEGLLLLTTDG----MVSHQVRSKKVEKEYYVQVDGDIDDAAILKLQTGVEIGIKGEKYLTLP-------CKVFKLENEPELPSNGRKPRdpkhGPMSWVSITIGEGKNRQIRKMTAAAGFP--------------------------------------------------------------------------------------
>UniRef50_B1ZYG8(70-232:266) Pseudouridine synthase n=3 Tax=Verrucomicrobia RepID=B1ZYG8_OPITP   E=4e-07 s/c=0.35 id=17% cov=54%
-----------LAMHKPRGLVC--TNEDPHNPETIFSVLpREFAKLRFFCAGRLDKDSEGLVILTTDGDLAHRLMH--PSNLVVKRYHVTLEKPFPAKRLPLLVKGVIAQGERLKV--------------------ERAALINPSVSHEATNLDVHMHHGKKREIRLLFTELGYPV-------------------------------------------------------------------------------------
>UniRef50_Q9ZJG0(68-252:262) Uncharacterized RNA pseudouridine synthase jhp_1352 n=37 Tax=Epsilonproteobacteria RepID=YE59_HELPJ  E=7e-07 s/c=0.31 id=27% cov=31%
----------VLVYHKPKGELV--SKADPLKRHVIYESLEKKYA-HFAPVGRLDFASEGVLLLSDSKAVVSALMHA----NLEKEYLVKIQGFVTRE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9HLH3(210-360:397) Predicted protein n=5 Tax=Magnoliophyta RepID=B9HLH3_POPTR   E=1e-06 s/c=0.37 id=23% cov=20%
-----------IALNKPKGYICSLGEKESKSVMCLLDDYFQSWDkrnpglpkPRLFTVGRLDVATTGLIIV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0VQK2(73-205:248) Pseudouridine synthase n=2 Tax=Alcanivorax RepID=Q0VQK2_ALCBS   E=3e-06 s/c=0.41 id=23% cov=23%
-----------LMINKPAGVVS--ATRDEHH-PTVLELLPRGQREGLHLAGRLDFNSTGLVLLTNDGAWSRRLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6XB83(278-427:455) RNA-binding S4 domain protein n=2 Tax=Methylophilaceae RepID=C6XB83_METSD  E=3e-06 s/c=0.36 id=26% cov=53%
-----------ILLHKPVGyvsgqaedgyepavVLVHPD-NHWAEDPV-QKEFRRGFLKGLAPAGRLDIDSTGLLVLTQDGRVARQLIG--EDSQTEKEYLVRVEGTLSDEGLRKLNHGLSLDGVQL---------KPAKVSWQNEDQ-----------------LRFVLREGRKRQIRRMCELVGLHVVG-----------------------------------------------------------------------------------
>UniRef50_C0BLA3(161-299:334) Pseudouridine synthase n=1 Tax=Flavobacteria bacterium MS024-3C RepID=C0BLA3_9BACT  E=4e-06 s/c=0.39 id=24% cov=28%
-----------ILLNKPKDFDSSAT--DASQPKSALGLVANATKSKIKPVGRLDKSASGLLLFTNDGELQTKLTK--PKNGFRKIYHA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1B371(14-132:194) Pseudouridine synthase n=1 Tax=Sulfurospirillum deleyianum DSM 6946 RepID=D1B371_SULD5  E=5e-06 s/c=0.45 id=27% cov=34%
----------LFVLNKPKGYLV--TRSDDLGRKTVYDLLPDWaFNEGWMPIGRLDLDSKGLLLFTTNGHISNALTTP---KKCTKVYEIWVRGHVMDEHIAEA--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7G1Y5(33-217:286) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G1Y5_PHATR  E=8e-06 s/c=0.29 id=25% cov=45%
-----------------------------------------QIRSKLHAIGRLDAETTGLLLLTNDGGLVHHVTnkdsvsHQHHGNPVFKTYEALVMGFYDNH----SPLLEKMRTQGVNIGDKYGGT----------TRPVDELIVKTNPTLKSTLVSLTICEGKNRQIRRMFHALG----------------------------------------------------------------------------------------
>UniRef50_B2UMD6(74-204:467) Pseudouridine synthase n=1 Tax=Akkermansia muciniphila ATCC BAA-835 RepID=B2UMD6_AKKM8  E=8e-06 s/c=0.41 id=26% cov=28%
----------VVLLNKPRGYVCSREAQGAIGT--VYDLLPPRL-RHLNYVGRLDADSEGLLIMTNKGELTQVLSH--PTGGIEKEYW-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6WWG1(104-325:347) Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC 29098 RepID=B6WWG1_9DELT  E=1e-05 s/c=0.24 id=23% cov=64%
---------------KPAGWHSVSLAGGGGRSLEAAipsLWAEGAVPPAWALLQRLDARTSGIVCAAVAededslAATVRDFRQAEAGGRCCKGYLALLSGSLEREACVRRALDMAQRRVVRVLDSEAADAAR-WTWFRPLyhWQGEACHAFARELCRRFslsvpslpdslTLAGCTIHRGARHQIRAHAAALGHALWLDGLY-------------------------------------------------------------------------------
>UniRef50_O66829(61-196:238) Uncharacterized RNA pseudouridine synthase aq_554 n=1 Tax=Aquifex aeolicus RepID=Y554_AQUAE  E=2e-05 s/c=0.38 id=23% cov=28%
-----------LMLYKPKGYLST-TEEDKKYPSFLELIREHFPSRKLFSAGRLDVDAEGLLLITDDGELAHRLTH--PKWKVEKEYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3ESK0(80-218:616) Pseudouridine synthase n=4 Tax=Bacteria RepID=A3ESK0_9BACT   E=2e-05 s/c=0.38 id=24% cov=32%
----------LFLFYKPKGIVS--TLHDPDEKTTLKDFFPQINP--LIHVGRLDIQSEGVLLLTNNGDLAQRILH--PRYEIPRTYLVKVQGVVKPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2W4E4(74-212:247) Pseudouridine synthase n=20 Tax=cellular organisms RepID=Q2W4E4_MAGSA  E=2e-05 s/c=0.37 id=20% cov=53%
----------VLMLHKPEGYTCSTSDPGRI-VYELLPERFMHRNPIVAPVGRLDRDSTGLLLLTDDGPLAHRITS--PKRHVPKTYEVTLARPLS----------------GEEGAVFASGTLMLRSESTPLAPAELVVSGPQTA-------RITITEGRYHQVKRMFAAVG----------------------------------------------------------------------------------------
>UniRef50_B8BRE9(4-151:221) Putative uncharacterized protein (Fragment) n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BRE9_THAPS  E=4e-05 s/c=0.34 id=17% cov=48%
---------------------------------------------KLHAIGRLDADTTGLLLLTNDGGLVHWITNPTSKQDsdpIPKTYEAVIMGH--HYLPQCDGPFTNNDNNTYPLMTLIQNGALLPQKYGGHTRPVDRLSVLSHPTRSTTRVSITISEGKNRQIRRMFHAIG----------------------------------------------------------------------------------------
>UniRef50_Q26G32(154-244:326) Ribosomal large subunit pseudouridine synthase F n=2 Tax=Flavobacteria RepID=Q26G32_9BACT  E=5e-05 s/c=0.56 id=20% cov=23%
-----------LLLNKPKGFI--APRKGERASKTVLDLMQSAGVANLHYVGRLGRQSVGLMLFTNDLEMANKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI00006CCA31(240-379:484) conserved hypothetical protein n=1 Tax=Tetrahymena thermophila RepID=UPI00006CCA31  E=6e-05 s/c=0.36 id=16% cov=23%
------------IFYKPRGMICSHDDPLKRPSVFN-YIYNNTKIKEPHIiaVGRLDYNSEGLILLTNDGDIAQCL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0BE12(504-662:690) Pseudouridine synthase, Rsu n=7 Tax=Burkholderia RepID=Q0BE12_BURCM   E=6e-05 s/c=0.32 id=24% cov=30%
-----------ILLHKPVGYVSGQAEDGYEPASVLITRANQWSGDRsplrfspqhlhaLAPAGRLDIDSTGMLVLTQNGRIAKQLIG--EQSDIDKEYLVRVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9NHG2(54-198:231) Ribosomal small subunit pseudouridine synthase n=1 Tax=Acholeplasma laidlawii PG-8A RepID=A9NHG2_ACHLI  E=0.0001 s/c=0.34 id=21% cov=22%
--EVIYKENVILSFYKPAGyLSSHKAEIYPS----LFELIGAPYNQYdLKIAGRLDYDSEGLVIL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9BZ50(70-215:249) Pseudouridine synthase n=49 Tax=Betaproteobacteria RepID=A9BZ50_DELAS  E=0.0001 s/c=0.34 id=25% cov=20%
-----------VLLHKPAGTecsqkPSTYPSIYSLLPLPLRLRPNKGAVQGVQAVGRLDQDTTGLLLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0F0K3(67-204:249) Pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F0K3_9PROT  E=0.0002 s/c=0.35 id=22% cov=38%
------------------------------------------------PVGRLDKDTSGLLIVTDDGQLNHCLTS--PKQHISKTYSVTLAEPLQGREAEIMAAGTL-----------------------LLENDDRPCLPAELIVHSPTQASLTLHEGRYHQARRMFVALG----------------------------------------------------------------------------------------
>UniRef50_B6AKQ9(85-232:298) Putative uncharacterized protein n=1 Tax=Leptospirillum sp. Group II '5-way CG' RepID=B6AKQ9_9BACT  E=0.0004 s/c=0.32 id=28% cov=21%
----------VFAFNKPRGVLVTRTDPGGRETICESIGRSSGQRtgmdmSRLMPVGRLDQASSGLILL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0AS26(74-204:372) Pseudouridine synthase n=1 Tax=Maricaulis maris MCS10 RepID=Q0AS26_MARMM  E=0.0004 s/c=0.36 id=28% cov=22%
--------------HKPDGLVT--THADPEGRETVFDAIPKDIG-RVISIGRLDLTSEGLLLLTNDGALARAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0M7H0(119-196:295) Ribosomal large subunit pseudouridine synthase F n=4 Tax=Flavobacteriales RepID=A0M7H0_GRAFK  E=0.0004 s/c=0.61 id=25% cov=24%
-----------ILLNKPAGFFVTGNP--EKGGKTVMELVARTTSAKVSPVGKLDNQAKGLLLFTNDGTLAKKLAK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3ABZ7(82-303:305) Pseudouridine synthase n=2 Tax=Bacteria RepID=Q3ABZ7_CARHZ   E=2e-64 s/c=1.12 id=33% cov=83%
-LDIVYEDEDLVVVNKKAGMVVHPAEGNWDGTLVNALLYHCQnlsgigGVLRPGIVHRLDKDTSGLLVVAKNDLAHQSLAEQIKEKKAVREYWTIVHGYLKNKeGIIDLPIGRHPRDRQKMAVV--SNGKTAQTVYKVLEEF----------NKGFTLIQAKLLTGRTHQIRVHFSYLGHPVLGDPKYGHQ------NNPFGVKRQMLHAIKLSFIHPRSGELLEFTAPLPEDFQRVLAKL--------------------------
>UniRef50_C7NAV5(99-322:326) Pseudouridine synthase n=5 Tax=Fusobacteriaceae RepID=C7NAV5_LEPBD   E=2e-63 s/c=1.09 id=31% cov=83%
-IEIIYEDNDLAVINKKAGIVVHPANGHYSGTLVNAILYHIKdlsginGEIRPGIVHRLDKDTSGLLIIAKNDKAHLKLSQMFHDKTVKKIYLAILKGKLNQKsGRIVTQIGRDKNDRKKMTVINDlNSGKTAITNYEVISQTE-----------KFTLVKVHIETGRTHQIRVHMKHLGYPILGDSVYGRTDTE---------KRQMLHAYKLEFQHPITEENLEFIAKLPEDFKKALKKCG-------------------------
>UniRef50_B0TGQ0(112-342:369) Pseudouridine synthase n=44 Tax=Bacteria RepID=B0TGQ0_HELMI   E=9e-63 s/c=1.05 id=32% cov=87%
-LEIIFQDADIAVINKPAGLVVHPAEGHWSGTLVNALLYHIKdlsginGELRPGIVHRIDKDTSGLLVVAKNDRAHIHLTEQVKDHRVRREYLAVVHGVIgAETGRVEAPIGRDPKDRQRMAVI--AGGKSAITHFRVLAR---------YPEQGFSLLHCRLETGRTHQIRVHLAHIGHPVAGDPKYGPRK------AAFGLTGQALHAWKLEFVHPRSGEPMRFQADPPEPFVQVLQAL---QMTPTNQR---------------
>UniRef50_Q6AJM1(98-326:327) Pseudouridine synthase n=1 Tax=Desulfotalea psychrophila RepID=Q6AJM1_DESPS  E=2e-62 s/c=1.05 id=30% cov=86%
----IYEDDSLLVLSKPPGIVVHPGNGNTEGTLVHGLLYHCreiggvGDAIRPGIVHRLDKDTSGAMVVAKDERSLRTLVDSFKERQVYKVYHALVCGIPKKYEGRIVAPIGRHSVHRQKMAISERTGKFAATNWQVVEVFET-------KDGPYSLLRVHIETGRTHQIRVHMSSIGCPIAGDQVYGSKRQNPAFA------RQMLHASRLRLPHPVTGRTMSFTAPLWQDFQEVLEDMDWSGAL--------------------
>UniRef50_A6DUC9(90-320:323) Pseudouridine synthase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DUC9_9BACT  E=2e-60 s/c=1.01 id=30% cov=85%
-LDIIYEDDDILVVNKPAGMVVHPGAGNYTGTLVNALLGRdldtfsamDDGSSRPGIVHRLDKETSGVIIVAKSAKNLDKLSRSFARRDVEKYYVALCRGTIRVGRDTITSHIGRSRSNRQKMenTNDSNRGKEAISHYKVLA-----------DNNGATLVKLKIDTGRTHQIRVHMSGINHPVVGDKLYGVRRLD----EKESPDRHILHAWRTRIIHPGTQEIMTFTAPLHDDFKSVCDKFG-------------------------
>UniRef50_A9IQ66(81-330:334) Pseudouridine synthase n=5 Tax=Bacteria RepID=A9IQ66_BART1   E=2e-60 s/c=0.94 id=30% cov=88%
-LDILYEDDHVIVINKPAGLVVHPGNGNWTGTLVNALIYHCGNSlsgiggvKRPGVVHRLDKNTSGVMVVAKNDLAHKSLSAQFSDHGrtcaLDRRYHALIWGTPhRNVWTIDASLGRSPHNRTKQAVVHKqtPHARHAVTHFSLLEKY----GTHADSTSFASLLECRLETGRTHQIRVHMAHIGHPLIGDTVYGNAFKTKSNTLNPTLKnaidqfnRHALHAASLTFEHPSSGKVISFSAPLPQDMAQLIKHL--------------------------
>UniRef50_D1BAB3(96-313:320) Pseudouridine synthase n=1 Tax=Thermanaerovibrio acidaminovorans DSM 6589 RepID=D1BAB3_THEAS  E=4e-60 s/c=1.07 id=31% cov=82%
-FRVVYQDQDLVVVDKPAGLVVHPAPGHWRGTLVHGLLYRYPdlmelnGVKRPGIVHRLDATTSGLMVVARNGLAMEGLVRAFKDRRVGKVYLAMAAGTLRGEGSVSLPIGRDPDNRKRMACV--PWGREALTRYRVIWSR-----------GGYSLVACQIKTGRTHQIRVHMRSLGHPLVGDRIYGG-----PCPEGFPLGRVFLHSWRLEFDHPRTGAPMSFICPLPPDLVRFI-----------------------------
>UniRef50_C8PVB8(143-378:380) Pseudouridine synthase n=2 Tax=Moraxellaceae RepID=C8PVB8_9GAMM   E=1e-58 s/c=0.97 id=30% cov=85%
-LDILYEDEAVLVINKPVGLVVHPGAGNGSGTLVNALLFHYPDSrtlPRAGLVHRIDKETSGLMVIAKDSQSQLHLINQLKDKSVYRLYQAIvlaSAAELARHRTIDAPIGRHPTQRTKMAVVSS--GKPAVTHLEKITAISDA----------VSLVSVRLETGRTHQIRVHLSNLGFPLLGDPLYGAARKNAILLKTLDddqkhivqqFQRQALHAYELGFIHPKTGEPIKVQARLPEDMQQLLDTL--------------------------
>UniRef50_C7RM94(107-332:375) Pseudouridine synthase n=11 Tax=Proteobacteria RepID=C7RM94_9PROT   E=2e-58 s/c=1.01 id=26% cov=86%
-LRIVFEDDTLIVLDKQAGLVVHPGSGNWRGTLLNGLLHHAPqlaRVPRAGIVHRLDKDTTGLMVVAKTLEAQTDLVRQLQARSVKRCYQALVRGIVEGAGIVDAPIGRHPTVRTRMAVV--SGGRPARTHYRVLERFVA-----------CTLIECALETGRTHQIRVHMTSIAHPLVGDPIYGGGASRVPQGAVF--PRQALHACRLALVHPASGKAMLWRSGVPADMAALIDRLRLESL---------------------
>UniRef50_Q2LWV4(85-318:333) Pseudouridine synthase n=1 Tax=Syntrophus aciditrophicus SB RepID=Q2LWV4_SYNAS  E=2e-58 s/c=0.97 id=30% cov=85%
-LSILYEDHDLLVLDKPAGLVVHPAAGHVSGTLVNALLFHCrdlagiGGVMRPGIVHRLDKDTSGLLVVAKTDAAHQGLALQFKKHQVGKTYQALVYGDPREKTGQIDLPVGRHPVERKKMSTKSRRGKEAATRWRIAERFGV-----------ATLLNVDIVTGRTHQIRVHLAAIGHPVVGDAVYGSSKRATTLTDPavkgrlKEMSRQALHAARLSFTHPVTHKILEFHAPLPADMEDLCA----------------------------
>UniRef50_A5EX53(86-319:322) Pseudouridine synthase n=1 Tax=Dichelobacter nodosus VCS1703A RepID=A5EX53_DICNV  E=6e-58 s/c=0.97 id=32% cov=84%
-LNILYADDDIIVINKPAGLVVHPAVGNHDNTLLNALLYHFPQTKHLprsGIVHRLDKDTSGAMVIAHSARAHTDLVRQLQNRSMGRIYLALVYGYITAGDTIDLPIGRHAKDRLKMAVRPD--GKPAITHYRIEERWQT-----------LTLLRVQLETGRTHQIRVHLSHHRHPLVGDKLYGARPFLASSLTELqrqalaEFPRQALHAVELHLHHPATNEIMRFTAPLPDDMTQLF-----------------------------
>UniRef50_Q87AR7(90-324:331) Ribosomal large subunit pseudouridine synthase D n=18 Tax=Gammaproteobacteria RepID=RLUD_XYLFT  E=7e-58 s/c=0.96 id=32% cov=85%
-LDILYEDEHVFVINKPAGLVVHPGAGNPDGTLVNALLHRDPalaAVPRAGVVHRLDKDTSGVMVVARTLQAQTALVEQLSSRQVHRQYLAVVVSALVSGGTVNAAIERHPRDRLRMEVSD--TGKEAVTHYRLRERFRA-----------HTALECRLDTGRTHQIRVHMAHLRHPIVGDRLYGGSLKLPKGgtdalvAMLRGFKRQALHAEVLEFLHPVRALPVRIVAPVPEDLCQLLAAL--------------------------
>UniRef50_C4FWV7(81-308:309) Pseudouridine synthase n=2 Tax=Firmicutes RepID=C4FWV7_9FIRM   E=5e-57 s/c=0.98 id=30% cov=85%
-LDIIYEDEDILVINKPAGLVVHPSKGHLKGTLVNGLLHYLNGNLstgsdfyRPGIVHRIDKDTSGLLVVAKHNAAHQALADQLLNHDMRRSYIALVHGQVKaPQGTIEAPLQRDPANRLR--WTVAKEGKYALTRFQVMENFE-----------NATLLDLELETGRTHQIRVHLEFIGHPLVGDPVYRKGLDHIKGSLVHDMTGQLLHAYALKLQHPRSGEWLEFKAPLPRRFEEALDQL--------------------------
>UniRef50_A4BJ00(4-243:249) Pseudouridine synthase n=1 Tax=Reinekea blandensis MED297 RepID=A4BJ00_9GAMM  E=2e-56 s/c=0.92 id=45% cov=91%
-LNIVYEDDVLLVVDKPSGLLMHPSWLDRRETDTLagrakAYLAQQSEGAKVHTVHRLDRPTSGLVVMCKDDHAAKALVEQFQEKTVNKRYWAICRGFAPVAETLDYPLIEEHDRIADKFADSDKPAQEAITEFRRLGITELAIPVSRYPKMRLSWMECVPVTGRKHQIRRHLKHLRYPILGDTRHGCRHLNRAVEGSFGELFMGLRAVEMSFQHPVTNELMTFNVGADNVWSCWLDRLGW------------------------
>UniRef50_Q4FN11(82-321:326) Pseudouridine synthase n=4 Tax=Bacteria RepID=Q4FN11_PELUB   E=4e-56 s/c=0.92 id=27% cov=87%
-LQIVYEDDDLLIINKPAGIIMHPGAGNYDETIVNALMHYNkdslstiGDELRPGIVHRIDKDTSGLIVIAKNNETHENLSHQFSEHTITRVYQLLIWGKLRPSSGKIDTFITRSSKNRQMMEVSNSKGKRAITNYKTIEIFEND------KTPTLSLVECRLETGRTHQIRVHMTHMGNSIMGDGKYKKKYKKLKNIDTnlenliYKLDRQFLHAQTLGFIHPRTNEEMVFTSILPQELENIL-----------------------------
>UniRef50_B0VJ94(89-338:351) Pseudouridine synthase n=1 Tax=Candidatus Cloacamonas acidaminovorans RepID=B0VJ94_9BACT  E=5e-56 s/c=0.88 id=31% cov=85%
-LDVVYEDEYLAIINKKAGMIVHPGFGNPEGTLVNAILYRFGENlssgkefNRPGIVHRLDRGTSGLIIIAKNDLTHAKLSDMFARREIKKTYFAITTGIPEPEKGEIETYLARSNKNPRTICVTNE-GRYALTHYKTIKTWHY-----------FALVEINPATGRMHQIRVHFAHIRYPILGDLLYNSRRYVQSLVPQnmkkkvtellvNHLRRQALHSWKLEFFHPITGYPISVSAPIPDDIQYTLNWL--------------------------
>UniRef50_B9YI75(99-327:329) Pseudouridine synthase, RluA family n=1 Tax='Nostoc azollae' 0708 RepID=B9YI75_ANAAZ  E=5e-55 s/c=0.94 id=30% cov=85%
-LDILYEDEQLLILNKPAGLVVHPAPGHLDGTLVNALLAHCanlpgiGGVQRPGIVHRLDKDTTGAIAIAKTDIAYQHLQAQLQAKTARREYLGVVYGVPKTEsGIINLPISRHPQDRKKMAIVPTEqGGRTAITHWQIRERL-----------SNYTLIHFQLETGRTHQIRVHSAKIGHPIVGDSVYGAGRSV-----GVNLAGHALHAWQLKLQHPISGDWIQVTASPPQTFTTLLEVLRRRS----------------------
>UniRef50_A6GP31(104-329:335) Pseudouridine synthase n=1 Tax=Limnobacter sp. MED105 RepID=A6GP31_9BURK  E=8e-55 s/c=0.95 id=31% cov=84%
-LPILFEDEHLLVVNKPSGMAVHGGSGSSFGLIECIRALRAETHQDLELVHRIDRETSGILIISKKRSALRKLQEQLRARSWKKYYKTLVLGhWPEALRQVDLPLLKTQSSEKEARVFVDESGDKACTKFKVIQCYKSSYSS-------FTLIQAQILTGRTHQIRVHTSANKFPIAGDDRYGNFEMNKQLA-RQGLKRMFLHAARLQLVHPATNETIVLEAPLAPEL---------------------------------
>UniRef50_C6XNC0(98-357:369) Pseudouridine synthase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XNC0_HIRBI  E=9e-55 s/c=0.83 id=28% cov=87%
-LDVLFEDEHLIILNKPAGLVVHPAPGSTSGTLVNALLHHCagqlpgiGGVARPGIVHRLDKDTSGVMVAAKTEFAHTGLSSLFQAHFMERAYLAVTRGAPRPLLGKIETRIARSTTDRKKMAVVREsrlsasaewhgeseedyeqKGKHAITNYKVLEQFGRIDATSGLPA--ATLTECRLETGRTHQIRVHMAHIGAPLLGDQTYGRYRGLKAHGSGPafetathackEFKRQALHAAILGFEHPVTGENLRFEVEPPEDM---------------------------------
>UniRef50_Q0F3G4(94-314:315) Pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F3G4_9PROT  E=9e-55 s/c=0.97 id=33% cov=85%
-IPVLYEDDSLLVVNKPAGMVVHGGSGHEAGLIEAL--KQSRGLDDLRLAHRLDRDTSGVLLMAKHLDALRRLTESFRERDMQKTYFALIAGHPyAHAGRMSSNLAKGVVRGGERMVVDSEEGKASVTDYQVMIEYE-------RHGFPYAMVALNPHSGRTHQLRVQLQHEGHPILGDGKYGEKAQLAA-YKSLGGKGLMLHAWRLRFTHPVSGKSLECKAPWPDNWSALL-----------------------------
>UniRef50_B4RVP9(28-260:265) Pseudouridine synthase n=1 Tax=Alteromonas macleodii 'Deep ecotype' RepID=B4RVP9_ALTMD  E=8e-54 s/c=0.91 id=49% cov=90%
-LPVLYQDEHIIAIDKPPGLLVHRSPIDKHETVFAVQTLRDQIGQHVFPAHRLDRPTSGVLVFSFSADTAAKLGKQMMDKQVVKQYHAIVRGFVHHTGYIDYALKYRYDKIADKHKRPQQPPQPASTMYESLAKFDVPEPVGRYQSARYSLVRLSPSTGRKHQLRRHMVHIRHPIIGDTTHGDGKQNKFAKSHFNFTHLALSCTQMGFSHPVTQKWITINGEMHSEMRQFTDRL--------------------------
>UniRef50_D0J9U5(87-333:344) Pseudouridine synthase n=2 Tax=Blattabacterium RepID=D0J9U5_BLASP   E=9e-54 s/c=0.86 id=27% cov=85%
-LNILYEDEDILVINKAAGMVVHPGFGNEKGTLIHGIKYHFKNNHQLYrlgLVHRIDKDTTGLLVLAKNEYAQKYLFQQFISKTIQRKYLALVWGNIqKQEGTISGFIGRDPNNRKRMtlFQRNFYRSRYSVTHYKVLERFKY-----------LTYVSCNLETGKTHQIRVHFKYLGHPLFNDSTYGGDKIFMKKYLSKksidffkdslnLLKRQALHAGSLSFIHPK-NRKCHFTCSIPEDFKKVLQKL--------------------------
>UniRef50_D2QPA6(11-234:244) Pseudouridine synthase n=1 Tax=Spirosoma linguale DSM 74 RepID=D2QPA6_9SPHI  E=1e-53 s/c=0.95 id=49% cov=87%
-LSILYQDTELVAINKPHGLLVHRSMIASDASEFAVQLLRDQLGQRVYPVHRLDRKTAGVLLFALSESMNAIMQQQFMEGAVQKTYLAIVRGYTPDELTIDYPLCKDDGNGAVGVL------QEAVTHLKTLRQTEIPVAFGKHPTSRYSLVELTPTTGRMHQLRRHMAHILHPIIGDRPHGCNKQNKLFKEHFEMNTMLLHAQRIEFTHPVTQETTTIAAPFQAEFRRML-----------------------------
>UniRef50_B5YAZ5(7-223:226) Pseudouridine synthase n=2 Tax=Dictyoglomus RepID=B5YAZ5_DICT6   E=2e-53 s/c=0.97 id=31% cov=82%
-LEVIYEDNHLLVVNKPAGILVQGDITKSTTLLEiskayIKEKYKKPGNVFLAIVHRLDKPVSGVVIFARNSKSAGRLSEAFRERKVEKEYIALCKGIFKVKKGTISESLLWVEKERKARVSQDDKSKNAITHYEVLEEFK-----------NLSLVRLIPETGRKHQLRAHLSYIGHPILGDEKYGGGRIFK--------DRIFLHCKKMAVPHPVRKDIMEFEAKIPDFWSEFLK----------------------------
>UniRef50_A0L8J2(101-325:328) Pseudouridine synthase n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L8J2_MAGSM  E=3e-53 s/c=0.93 id=37% cov=83%
----LHRDGWILVLNKPAGIPVHGGSGHQWGVVdaVRASLEKLGIEAQAELCHRLDKETSGLLLFGLRPRAVRLLTEAMRENQVTKTYLTLVQGVPaARQGVINQPLSKGNVRGGERMVVVEQGGQRAVTHYRVLRSYGV-----------ASLLEVQLETGRTHQIRVHMQWLGHPVAGDGKYGDKAFNKWMRER-GLKRLFLHASELAFRHPENEQKLAYQAPLDDELTRVLE----------------------------
>UniRef50_A1HR26(75-292:301) Pseudouridine synthase, RluA family n=1 Tax=Thermosinus carboxydivorans Nor1 RepID=A1HR26_9FIRM  E=2e-52 s/c=0.95 id=33% cov=82%
-LHIVYEDDFLLIVNKPAGLLVHPTSDPTEPTLAhgiLYYLHSKGALGAFHPIHRLDRNTSGLVAIAKHPHIQHALSGGGAKG-LKRLYLAVVTGIPSSlMGRIDAPIGRHPNSIIKRVVRSD--GQPAITLYRVLSTFSM-----------ASLVELELLTGRTHQIRVHLSHIGHPLLGDDLYGG--------ATDLIRRQALHAASLSFRHPATDKVLTLTSPLPPDLADLIQLL--------------------------
>UniRef50_C5J6Q2(82-298:306) Pseudouridine synthase n=1 Tax=Mycoplasma conjunctivae HRC/581 RepID=C5J6Q2_MYCCR  E=4e-52 s/c=0.95 id=28% cov=81%
-FEIVYQDNDIIVINKPKNLVVHPGNGNWDKTLVNGLLHEFatnlsdvNGEIRPGIVHRLDKDTSGLLLVAKNNQAHKYLAKQLENHEIERKYIAIVVGKIPHTKMRINLPIGRDNQNRTKKVVSSFNSKNAITNVELINTF-------VYKNEHFSIVKCILETGRTHQIRVHLSHIGYPIYGDPVYGKKIDDL---------GQRLHAYEITFKH-LDGRLMNFKTEMPDEFK--------------------------------
>UniRef50_Q5Z8P2(140-425:445) RNA pseudourine synthase 2, chloroplastic n=6 Tax=Magnoliophyta RepID=PUS2_ORYSJ  E=2e-51 s/c=0.72 id=27% cov=87%
-LDIVYEDDHLLVVNKPAHMVVHPAPGNANGTLVNAILHHCKISTftclarnsiddecpdssdddidvfdidqfttgevssevrealvRPGIVHRLDKGTSGLLVVAKDEHSHAQLAEQFKLHTIRRVYISLTCGAPnPNSGRIEVPIARDPNNRIRMIATPGSGhryARHAASRYKVREVF---------AGGGSALVEWRLETGRTHQIRAHAKYLGIPLLGDETYGGTKSMALSLLRPRtpsryhcdlsnmiskIDRPCLHAALLGFKHPHSGKILEFSCPPPDDFTEVLNEL--------------------------
>UniRef50_Q8ZFU1(95-313:320) Ribosomal large subunit pseudouridine synthase C n=102 Tax=Gammaproteobacteria RepID=RLUC_YERPE  E=3e-51 s/c=0.93 id=35% cov=83%
---ILFEDDYLLVLNKPSGTAVHGGSGLSFGVIEGLRALRPE-ARFLELVHRLDRDTSGVLLVAKKRSALRSLHEQLRLKSMQKDYLALVRGqWQSHCKAIQAPLLKNIMQSGERVVKVSSEGKPSETRFKIEERFE-----------HATLVKASPVTGRTHQIRVHALHAGHPIAFDDRYG-YREFDQQLQGTGLHRLFLHAAALRFEHPNTGETMRIEAPLDNQLRHCL-----------------------------
>UniRef50_Q2IJ40(100-353:353) Pseudouridine synthase n=7 Tax=Cystobacterineae RepID=Q2IJ40_ANADE   E=6e-51 s/c=0.80 id=29% cov=90%
-LAVLHEDADLIVLDKAPGMVVHPARGTPHSTVVNALLHRLGLPaaagpdgalPRLGLVHRLDKDTSGCLVVAKTEAALAALQAQWKGRSVEKVYLALCHGALAAAGRLDTPYGRHPRDRLRFTGR-LASSRRAITEWRVREAF----------GPAASLAEVTLHTGRTHQIRVHLSEAGHPLLGDAVYGGTRREARLAPDDPARraaeavgRQALHALRLGLDHPRTGRRLVVEAPVPADLRAALEILraaqpGNAGPAPRRRR---------------
>UniRef50_Q1DCE5(82-310:310) Pseudouridine synthase, RluA family n=2 Tax=Cystobacterineae RepID=Q1DCE5_MYXXD  E=1e-50 s/c=0.88 id=35% cov=82%
-LRVLYEDADVIAVDKPAGVSAQPTEGRVGDSLV--DLVGAKLGRPAGLVHRLDRETSGVTVFGKTAEATSALAAEFREGRARKRYVAATGPGLPPSGTVDLPLSKDPSRPGRWRATRAANGVPALTDFHTLSS-----------GPAFCVVELLPHTGRTHQLRAHLTALGAPILGDARYGG----AARAEGVEAPRCLLHAQALELGHPRTGKLLRIEAPVPEDLMRFF-----------------------------
>UniRef50_A4FXG9(81-296:298) Pseudouridine synthase, RluA family n=5 Tax=Methanococcus RepID=A4FXG9_METM5  E=2e-50 s/c=0.93 id=24% cov=82%
LLCVIYEDDDLLIVDKPKNMVVHPTKNVLSGTLANAisnHQKINNQNYKIRFVNRLDMDTTGLLIIAKNSYSHQQLAKQMDEGILEKIYIVVVNGHLDSKEGVIEDSIDLNDDGIKREL--STFGKISKTKYKVIEEF-----------NNVSVLEIKLLTGRTHQIRVHLSSFGNNIIGDTLYGKTAD--------LIERQALHSHILRFIHPITKENMEIRSKLPDDMENLIKNL--------------------------
>UniRef50_C0Z877(94-307:310) Pseudouridine synthase n=1 Tax=Brevibacillus brevis NBRC 100599 RepID=C0Z877_BREBN  E=4e-50 s/c=0.93 id=33% cov=81%
-IDILYEDDHLLIANKPAGMMVHPIKQETDTLVHALAAVLAARGEQtsVHPVHRLDKDTSGAILVAKSSYGHQLADRLLREGGIHREYLAVASGVLsEGAGTIDAPIGRDARHPTKRRVVES--GDPAITHYEVQQTSE-----------EMTLARVWLETGRTHQIRVHFAHIGHPLAGDTMYGGARG--------LLRRQALHASKLSFLHPLLEKEIVVEAPIPSDMKRLMQ----------------------------
>UniRef50_Q83G23(75-296:303) Pseudouridine synthase n=2 Tax=Tropheryma whipplei RepID=Q83G23_TROWT  E=7e-50 s/c=0.90 id=31% cov=83%
LLRVIYSDDDLFVIDKPAGVAAHASPGWCGPTVTgclSGLLAACGPQDRQGIVHRLDANTSGLMVLAKSDLAYHNLKAAFRDRAIHKRYKALVQGYPdPSSGVINAPIGRDLKHRDRFCI--DYSGRDAVTQYSTEEVY-----------PGFTLLSVAPKTGRTHQIRVHFSALRHPLVGDVKYG---ADPVFSQKVNLKRQWLHAYHLSFTHPVSGVFVEFESRIHEDLQESL-----------------------------
>UniRef50_Q8ERS8(103-319:322) Pseudouridine synthase n=2 Tax=Bacillaceae RepID=Q8ERS8_OCEIH   E=1e-49 s/c=0.91 id=28% cov=82%
-LDIIYEDAYCLVVNKPAGQACLPSMNHRHNTLANgltYYYQKNSIPSTVHIVTRLDVNTSGLVLVAKNQYVHSLFSRMQQEGNINRVYEAIVHGEVsPTSGIVDAPIARKEGSIIER-TVDMRNGKYAKTNYRVL-----------YADSIASWVEIKLETGRTHQIRVHFQYLGHSLYGDNLYGGSKDIML--------RQALHCKQITMMHPIKNQPIQLEASLPEDMGILLKRL--------------------------
>UniRef50_A9GIV4(108-348:350) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GIV4_SORC5  E=3e-49 s/c=0.82 id=35% cov=88%
-IPVLHEDDALLAIDKPAGLPVHPTARYHKSTVIKMME-AARPGERLFLAHRLDRETSGVLLLCRTPEADRTVKAQFEERTgVVKRYAAIAWGWPERDtFRVELPLELDDASRYKVKMRVAPPGRglASATACEVLGRRADPLT-----GRRYALVRCTLETGRQHQIRVHLAASGLPLVGDKLYGpdegmfargaDGVLTDDDRRALELDRHALHAALLELTHPMTGERVRIEAPLSDDLRTFWDAL--------------------------
>UniRef50_B1ZRU1(5-265:268) Pseudouridine synthase n=2 Tax=Opitutaceae RepID=B1ZRU1_OPITP   E=1e-48 s/c=0.75 id=33% cov=90%
--PILFEDDAMIAFDKPSGLLIAPDRWDKQ-RENLMGLVHARFGHGVANVHRLDADTSGLLLCAKTKPALDFLSGQFQAKTVQKTYLSLVVvlppeeamkvvkpirddaGGLPDAFQVDLALGQDERQPGRMRVFKGRGGKDCVTDFRVLERF-----------GRFALVSCHPQTGRTHQIRVHLAAAGAPILNDPFYGNpeiklllsdlkRRYKGRDEEKPLIDRLALHASELTFRHPATRELLTLQAPLPHEFEIALKYL-RKFAAPASRRPP-------------
>UniRef50_A6LDZ7(340-549:549) Pseudouridine synthase n=26 Tax=Bacteroidales RepID=A6LDZ7_PARD8   E=1e-48 s/c=0.93 id=37% cov=76%
-LDILYEDDYLLVINKPEGMLSVPGKGDADSVYQRLSIL-YPEATGPIIVHRLDMATSGLLLAAKTKEAHQNLQAQFKNRTIQKRYIALLEGEVPQDEGEIRLPLCPDPLDRPRQIVSEEFGKPALTHYRVLER-----------TSGKTLIAFYPQTGRTHQLRVHAAHplgLHCPILGDELYGRKAE-----------RLYLHAEYLAFTHPITSERIEIQ----------------------------------------
>UniRef50_B9DS29(76-291:301) Pseudouridine synthase n=85 Tax=Firmicutes RepID=B9DS29_STRU0   E=3e-48 s/c=0.90 id=29% cov=82%
-LDIVYEDDHFLVLNKPVGYASIPSAIHSNtiaNFIKAYYFEQNYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKRSIEKRYFALVSGNgqLPDFGEIVEPIGRSKDSIITR--TVDPMGKYAKTTYEVVARFAE----------NVHLVDIKLHTGRTHQIRVHFSHIGFPLLGDDLYGG-------RMDLGIERQALHCHFLSFFNPFTENESIHTINLTEDFENVI-----------------------------
>UniRef50_C1ZMP6(5-244:246) Pseudouridine synthase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZMP6_PLALI  E=3e-48 s/c=0.81 id=32% cov=90%
--HILFEDNHCLVVEKPAGVLTMGDETGDENMVQLAmddlkIRHQKPGNVYVGLVHRLDRPVSGVLLLAKTSKAASRLSAQFREREPEKVYLAIVEGQLnPAAGEIVDWLIKDQERNHTRVTSPqTPGAKQAKLRYRQLETLVTPEGIR-------TLVEVQPMTGRSHQIRVQLAHAGASILGDLRYGSKTPLGKM--------IALHARSLTFEHPVQKQPLTIYAPLPSDWKPFMNPLLWEKFQTAGESAAESS----------
>UniRef50_Q7UUI8(84-320:321) Pseudouridine synthase n=1 Tax=Rhodopirellula baltica RepID=Q7UUI8_RHOBA  E=7e-48 s/c=0.81 id=27% cov=88%
-FEIVFEDEHIIVVNKSAGTLTVPTDRGEPNSLvdrVSIYLSYSKSKKEAFVVHRLDRETSGLLVFGKHEPIADLLIEQFKDRRPTRVFHAIVAGNVSEDEGTFESHLATGSNLDRYETRPGKDTDQAITHYKVVRRLAERESSH---GEETTLIEAQLETSKRNQVRVQFANAGHPVLGDPRY---KPKEATHARWHRKRMALHASTLGFFHPVSGEPVNFDTPLPSAMEKFVA--GARG----------------------
>UniRef50_D2R7R1(6-225:245) Pseudouridine synthase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R7R1_9PLAN  E=8e-48 s/c=0.87 id=29% cov=83%
-FEILLEDSAVLVVNKPAGILTQAPLGIDSLEWQIKRYLQSTEKsevPYLGVPHRLDRPVSGCICFAKNQKAARKISQQFEARLVQKTYWALVSGIVHPTRSTWVDHLKKLDGEPRTIVVDerDPEGKNAILHYELLETRE-----------GRSLLAITLETGRTHQIRVQCGSRGFPLLGDRLYGSAEPFGPLAADERDQLIALHARTLAFRHPVTKEDLIFTAQVPAIW---------------------------------
>UniRef50_B6BTS8(86-306:306) Pseudouridine synthase n=2 Tax=Betaproteobacteria RepID=B6BTS8_9PROT  E=1e-47 s/c=0.87 id=29% cov=84%
--HIIYEDEWLLVVNKPSGLAVHGGSGIDFGLIEHMRHIKPEY-KFLELVHRIDKNTSGVIVIAKKRSALRSMQELFRNKKIKKNYLvAVKGNWDSKKKEVSLRLEKKQTSEGHHVNVVEDplRGKLSKSIFYLVKQMQKQ-----------SLLSAQIITGRTHQIRVQLAFLGFPVLGDDKYGDFALNKKL-QSSGLKRMFLHAHKLSFFHPFTEEKVELTADLPIELRKFFDE---------------------------
>UniRef50_UPI00016C4782(62-272:275) RNA pseudouridylate synthase n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C4782  E=1e-47 s/c=0.91 id=36% cov=80%
-LEIVHEDAHLVVIDKPSGLLTVATESEKLDTAFVRLsdYLRARNAGRPFVVHRLDRDTSGLLLFARSAEVRDQLQGNWE--ELTKTYLAVVEGRPESSEGGVENYLTEGRDLRVRASpRPGPDGKRAASRYTV-----------RQTRGGYSLVEVEIETGRKHQIRVHLAGLGCPVAGDKMYG--------ATTDPVRRLGLHAWRLSFDHPFTLERLELEAPLPSALAR-------------------------------
>UniRef50_D2QJH0(89-304:308) Pseudouridine synthase, RluA family n=3 Tax=Bacteria RepID=D2QJH0_9SPHI  E=2e-47 s/c=0.88 id=32% cov=80%
-LTILYEDQFLIVINKQAGLLSMATNKERDRTaygILSEYTKKENPKNKIFIIHRLDRETSGVMMFAKSEKVQRLMQESWNATTKERTYVALVEGIPEPPQGTITSYLRESKALIVYSSQNPDTGQLSITNYTVTKT-----------GNGYALLELELETGRKNQIRVHMQDIGHPVAGDEKYG--------AESDPIGRLGLHAEVLAFEHPITGVPMRFDAPIPKSFL--------------------------------
>UniRef50_A0L7F8(16-240:255) Pseudouridine synthase n=6 Tax=Proteobacteria RepID=A0L7F8_MAGSM   E=3e-47 s/c=0.85 id=32% cov=83%
----LYRDGLLLIINKPAGIPVHAGPGGGANLEALFGGLRFGLPKAPALAHRLDRDTSGCLVLGRHAKALSKLGKLFSQGKVQKTYWAVVQGGPPQaQGSMDFPLYKISTaQQGWRMVVDPEQGKSSLTLYRVLGRSAT-----------HSWLELTPKTGRTHQIRVHCAHVGLPIEGDLQYGAAPSEPQLT-------LHLHARQIILPISASKAPINVSAPPPRAMRGLLEQCGYRA----------------------
>UniRef50_D1VV86(81-292:300) Pseudouridine synthase n=1 Tax=Peptoniphilus lacrimalis 315-B RepID=D1VV86_9FIRM  E=4e-47 s/c=0.90 id=30% cov=81%
-IDICYEDYDLLIVNKEYNCVTHTAKDDSKDTLLNYLAGyfeKNNIKRKVRFVNRLDRDTSGLIIVAKNSYAHAKIMDEFSNNQVDKIYLAICRGDFKEKQGEIVKKISLCQDGIRRE-VDDDNGKYAKTKYQVLKDNKKLALVKLKL-----------FTGRTHQIRVHLKSIGHPIIGDKLY-----NDSNEEQNLMNRQALHSYSLSFKLPRTGELKTFTAKLSDDM---------------------------------
>UniRef50_B9MS57(77-286:293) Pseudouridine synthase n=1 Tax=Anaerocellum thermophilum DSM 6725 RepID=B9MS57_ANATD  E=5e-47 s/c=0.90 id=28% cov=80%
-IDILYEDNFFLFVNKPSGLPSHPSKGHYFDTIANYvEYYLNSKNLTSHIINRLDKDTSGIVVFAKNSYFHSIVSYEFEKRRVDKTYIAIVHGILTKKSGLIEKPIKRSDDGIKREIHQD--GSFASTYYEVIDSFE-----------NFSVLKLKPITGRTHQLRVHLSSIGHPIVGDYIYGEEKTQNT--------PLLLHAYSISFNfKLINNKVYDITSPLPHYFHE-------------------------------
>UniRef50_A6DMG7(10-240:246) tRNA pseudouridine synthase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DMG7_9BACT  E=6e-47 s/c=0.82 id=44% cov=89%
----LYEDEYLVVAKKLAKISVHRSEMCRDRRTLLTMVRNKLGGQYVYAVHRLDRPVSGPLLFAKSPEMCRELQKQFNEKTVEKKYIALVRGWLEGKGKVDKQLLKKSNGTI----------QDCLTRYRGLATAEIDEPLGKFPTVRYGLVELEPVTGRYHQLRRHMRDLAYPIIGDSTDGDSHQNRFFREKFELRRLMLHCFYLSFKHPVSQELIKIYLEPDRDLLRIYEQLGMYEQFKQLER---------------
>UniRef50_Q8D220(86-308:314) Pseudouridine synthase n=1 Tax=Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis RepID=Q8D220_WIGBR  E=7e-47 s/c=0.85 id=21% cov=84%
----IYEDDDILVINKYKDVIVHPGCDKHENTLLHDILFNYPDSKNLYragIVHRLDKDTTGLMLIARNSFSQKKLIKLLKLRLINREYRAVLLGKIICDGTVSAPIIRNSKNRTRM--KVHISGKESITHYKIIKNF-----------NDFSYVKINLESGRTHQIRLHMSYINHPVLGDFVYGNKKNKYIKtlyKSIFNISRHALHARKIKFIHPINNCLMVHKIDLPDDMKILLKNL--------------------------
>UniRef50_C8PTH9(13-229:240) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PTH9_9SPIO  E=9e-47 s/c=0.87 id=32% cov=83%
-IPIVYEDEALCIVNKPYGIPVQGGA---HISVCLTEILSKQLGSEIFPVHRLDKETSGLLVTAKSADAARSCRALFESQAVEKEYLALCFGGFEPSAHKKPVKKLLPEGIIDTPVVENGSPKPASSAYKLLASTDA-----------YSLFSVRLHTGRMHQIRIHLAGIGYPIIGDDKHGNFALNKQLWKTARIKKLQLCAYRLMF--PIGGKKCLFTVPAPEHIQAAID----------------------------
>UniRef50_Q03E91(78-290:294) Pseudouridylate synthase, 23S RNA-specific n=2 Tax=Pediococcus RepID=Q03E91_PEDPA  E=1e-46 s/c=0.89 id=32% cov=80%
-LDIIFEDKNWLLVNKPAGLTAVPGPSDREDTLVNRIKGHWQAIESknmmPHLVTRLDRFTSGITLVARHQVSNSLLSEQVAHHKIKKIYLAMVDGVVQAEKGTFNQSLGLAADGIHREVRDD--GQQATTSFKVLKRFENQ-----------TLVQIHLKTGRTHQIRVHFANAGHPLVGDQLY-------DGPMDRGIKRQALHASSIRFFDPFIDEKVSFTAELPDDLKQ-------------------------------
>UniRef50_Q4A7R4(82-301:304) Pseudouridine synthase n=5 Tax=Mycoplasma hyopneumoniae RepID=Q4A7R4_MYCH7  E=2e-46 s/c=0.85 id=28% cov=83%
-FEIIFQDQNMILINKPKNLVVHPGVGNWKNTLVNglishFDSLEQLDHIRPGIVHRLDKDTTGLLLVAKNAKAHSFFVNELANRQIKRFYKAIVIGKvLHKFMKINLPIGRDLKNPLKKTISF-FNSKPAITNVELIKHF-------NYQNQDFSLVKCQLETGRTHQIRLHLAHIGYPIYGDPIYGKKIDEL---------GQRLHAYKLVFKD-LNGLSREFQADLPEEFNIAFEQ---------------------------
>UniRef50_Q6MMV3(50-282:290) Pseudouridine synthase n=2 Tax=Bdellovibrio bacteriovorus RepID=Q6MMV3_BDEBA  E=8e-46 s/c=0.80 id=42% cov=88%
LVELLYKDEYFIAVNKPSGFHVHPHENVQHRVSrdkICLYHARRMMKQHVYPVHRLDAGTSGVLLFALSSESASKLCRLFTERATHKTYQAVVRGFVKEEGEVQLPLELDSTGDLV----------DAHTSFKRLATVEFPVAVGkKFPTARYSWVEVTPHTGRYHQIRRHFNRISHPLLGDAVHGDSHHNRFFRNHLEIEGLCLKALRLEFTHPWSGEKVSIEAPPCDKWKKI--QLLFDPALP-------------------
>UniRef50_C1AE05(269-475:476) Pseudouridine synthase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1AE05_GEMAT  E=1e-45 s/c=0.89 id=29% cov=78%
---VVYEDDHLLVVNKPSGMLTVPGRGPTMQDCVMTRLRaRYPDATGQMVVHRLDLDTSGLLLAAKDPITASALQRLFSLREIDKHYVAWLDGVVTDDHGHIHLPLRMDVDDRPRNIHDPVFGKPAHTEWQVMARTD-----------GRTRVRFTPHTGRTHQLRVHAAHpdgLDAPIVGDRLYGRTAPDED-------ERLQLHAERLAFVHPVSGAKVVVEQPAP------------------------------------
>UniRef50_Q2IJ07(11-234:241) Pseudouridine synthase n=6 Tax=Cystobacterineae RepID=Q2IJ07_ANADE   E=1e-45 s/c=0.83 id=31% cov=87%
---VLHEDAALLAVDKPAGRLVIPGREGGEPSLREELEARFG---RLWVVHRLDRNTSGVLVLARTAAAHRALNLAFDRGEPRKRYLALVRGVPPAEQRIEVAIAPARKGRMRPAAPDDPRGKPSATVVRRLEAY----PSHPLGGGPLALVEALPETGRTHQIRVHLAAAGTPLALDPAYGDAAPLLGPGGEPVLARTPLHAARLALRHPADGRELVLEAPLPADLAGVLALL--------------------------
>UniRef50_D0LGK2(70-299:304) Pseudouridine synthase, RluA family n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LGK2_HALO1  E=2e-45 s/c=0.80 id=27% cov=85%
-VRIAYEDAHVVVIDKPVDVSSVPYERRETGTAMDLLreawrkLRPDAGRTPLHVVHRIDKATSGLLAFAKTKRAELGLAAQFRQHTLERAYLCVAHGAVR-AQRIESRLVRDRGDGLRGSTRAPNQGKRAVTHVEVLEEL-----------ARASLCQVRLETGKTHQIRIHLAERGHPLVGERVYKRDAEFR-GHTLIDAPRLMLHAATLGFAHPITGERVFVESPLPENFAAVLARL--------------------------
>UniRef50_C7LR44(18-228:243) Pseudouridine synthase n=6 Tax=Bacteria RepID=C7LR44_DESBD   E=2e-45 s/c=0.87 id=31% cov=80%
---IIYEDRDIIVVNKPAGMLTMATETEKTRTAyyALTDYVRKGNAKsryRIFIVHRLDRETSGIVLFAKTEVAKRTLQDQWED--TTKIYAAVVHGQMGKASGMLSSHLVESGVHKVYATRDAALGKLARTAWTVLKER-----------GGYSLLDVTLLTGRKHQIRVQMADAGHPIAGDKKYGVKGDT--------FSRLALHARSITFAHPFSGRSMTLDAPVPSVFAQL------------------------------
>UniRef50_D0XS67(113-333:350) Pseudouridine synthase n=1 Tax=Brevundimonas subvibrioides ATCC 15264 RepID=D0XS67_9CAUL  E=4e-45 s/c=0.83 id=33% cov=84%
---VIYEDDLVIALNKPWGLAVQGGTKTTRH-VDRLLSAWGEGMERPRLVHRLDRDTSGVLLLGKGPEAAKRLAGAFARRQAKKTYWAIVMGLPKPADGQISVHLKKSGindyEIMRPADPKDPGAEPAETAYAVISH----------AAQRASWMALRPFTGRTHQLRAHMKAIGHPILGDPKYGDDASTQLSGPLK----LQLHARRIELDHPAGG-TLVVEAPISAELRAGFEHFGF------------------------
>UniRef50_C1E0I0(71-318:318) Predicted protein n=2 Tax=Micromonas RepID=C1E0I0_9CHLO   E=5e-45 s/c=0.74 id=28% cov=88%
----LWEDEHLAVVSKPAGMLTHPNEASGGATRTLVEALLDAFGDEGlsaingadarGIVHRLDKPTSGAMLVAKTDLAHAMCVAAWYQRKVTKTYLALVEGVPGRRRGRRRGDDGDA---MEGTCVAPADGRPARSDWRVVETF--GEEDGDDAEQLCSLVEVTPRTGRRHQIRQHMgMALDAPLVGDPLYrrGKRPNTPATAAPFLVGKpgsvLFLHSAALALRHPVTGEALSFSDPLPAAFEGLVSALRRR-----------------------
>UniRef50_B6G997(7-227:227) Pseudouridine synthase n=1 Tax=Collinsella stercoris DSM 13279 RepID=B6G997_9ACTN  E=7e-45 s/c=0.83 id=35% cov=83%
-LRVLYRDPWLMAVDKPAGIIVHGDGtGAPTLTDAVRAHLvasgEASASAAAQALQRLDRDTTGIVLFSLDKEAQPAFDRMIAERSIQKRYLAIVHGRFPAAKTMCQPLGRDRHDSRRM--RVSRTGKPAHTDAKRIAYAKADARAPER-----SLLAIDLHTGRKHQIRVHLAHAKFPLLGDSLYGGPSCSG---------GLMLHASELSFTHPITGAPTHIQAPYPARFQRIMSQ---------------------------
>UniRef50_Q2CAH0(12-214:215) Pseudouridine synthase n=3 Tax=Proteobacteria RepID=Q2CAH0_9RHOB   E=1e-44 s/c=0.90 id=32% cov=78%
-LAVLHEDHEVVLVDKPAGLLSVPGKGEHLADCLLARVQAAF--PTALLVHRLDRDTSGVMIFALTPHAQRHLGLQFEKRQTRKTYVARVAGRIADKTGTVDLPLIVDWPNRPKQMVDHENGKPAVTDWRVVRASDAE-----------TRVRLFPKTGRSHQLRVHMLALGHPILGDPFYAEGPARAH-------PRMMLHSETLQFRHPDGGRGMRITAPAP------------------------------------
>UniRef50_Q28K21(14-216:217) Pseudouridine synthase n=11 Tax=Proteobacteria RepID=Q28K21_JANSC   E=2e-44 s/c=0.89 id=31% cov=78%
-LDIIHEDHDLLLVNKPAGLLSVPGKGEHLSDCLIARLKIAF--PEVLLVHRLDMDTSGVMVFARTPHAQRHLGLQFEKRHTKKAYVARVWGEVTDKDGHIDLPLIVDWPNRPLQHVNHETGKPAQTDWRRIRVED-----------GTTRMRLFPKTGRSHQLRVHMLAIGHPILGDPFY-------ATGPALAFPRLMLHAESLKLRHPDGGIGMTFRARVP------------------------------------
>UniRef50_A8UMR7(358-560:561) Pseudouridine synthase n=1 Tax=Flavobacteriales bacterium ALC-1 RepID=A8UMR7_9FLAO  E=6e-44 s/c=0.88 id=32% cov=77%
-LEIIYEDDFLVVLNKPHEFLSVPGKTIKDSVLTRMQNY-LPDATGPLLLHRLDMSTSGLLLVAKNERTHKNLQKQFIKRIVKKRYVALLNGKLEPSEGTIDLPLRVDLNNRPRQLVCDEHGKLAKTKYEVIE-----------IKNNKTRIHFYPITGRTHQLRVHAAHykgLNMPIIGDDLYGTAS-----------NRLHLHAEMLSFEHPVKREWVSFSCKAP------------------------------------
>UniRef50_B1ZUV5(43-272:279) Pseudouridine synthase n=2 Tax=Opitutaceae RepID=B1ZUV5_OPITP   E=1e-43 s/c=0.77 id=27% cov=85%
---IVHEDERLLVVAKPGDVVCHPSKAGPWSSLVGA-VREFTGLATVHLVFRLDRETSGIVVLAKDPKTASRLQVAMQERKIGKAYVAILTGAMREPVTVDQPLGDDVASPVFVKSAVRADGQRSVTHFSPITVAADDA---------FSLVRVVTETGRKHQIRAHAQWLGHSLVGDKIYGPDARcyldfidtgwTPALADKLLLPRQALHCAEIDLT--RTGLAHVFRAPMAEDMRRFCAERG-------------------------
>UniRef50_Q31NG5(338-542:543) Pseudouridine synthase n=2 Tax=Synechococcus elongatus RepID=Q31NG5_SYNE7  E=3e-43 s/c=0.86 id=33% cov=73%
-LPILYEDADLLAIIKPAGLLSVPGTRGLQQASAIQLLRQQFPDLPTYcVVHRLDQATSGILLVARNRPTQVALFEQFRRRQVHKVYEALLEGQPDCTAGTIDLPLRPDWTRRPYQLVDRDRGRPALTYYRCIDQ-----------TGDRCRMELEPITGRTHQLRVHMAHpegLGQPILGDDLYGQSS-----------DRLYLHARSIRFRHP-------------------------------------------------
>UniRef50_B2S2H8(3-213:216) Pseudouridine synthase n=2 Tax=Treponema pallidum RepID=B2S2H8_TREPS  E=8e-43 s/c=0.83 id=34% cov=81%
-LPIIFQDAAVVAVDKPAGLAVQPGAR---VRVCVVDVLQKQLGVRLFPLHRLDKDTAGVLLFAKHARAAALYQGILGSMRVIKRYRALCFGRPPRECGDIRVPIRTGTAARRRQVV-----RAAHTAYRVLRATDT-----------HTYLELTLHSGRTHQIRIHLAALGCPIIGDDKYGDFARNKACARAWGVKRLQLFAHSLVL--PCACKPLVLRARMPVHFLRALD----------------------------
>UniRef50_B4UMB0(77-308:312) Pseudouridine synthase n=4 Tax=Anaeromyxobacter RepID=B4UMB0_ANASK   E=1e-42 s/c=0.75 id=28% cov=84%
-LSVLLERPRYLVVEKPAGVAVHPLAPGEGGTLANAVAARHPECAEASPepreggaVQRLDLETSGCVLFARDPEAWEALHAQLGAHTVDKVYLALAVGRLPAGGVCSVPLAQRGGRVVPAPDLEAEErlqarglrPRPAETHYEPERRF-----------ADHTLLRVRIVTGVMHQIRAHLALLGHPVAGDALYGG-----AAAGLPGLERQFLHAWRLAFDDPDGAGRVAVESPLPPELEAVLARL--------------------------
>UniRef50_B3WCK2(77-296:300) Pseudouridine synthase n=8 Tax=Lactobacillus RepID=B3WCK2_LACCB   E=1e-42 s/c=0.80 id=26% cov=82%
-LAISYEDDDYLIVNKPAGVASIPAVGRQNNSMANMvkayLIKTKAESQAVHVVTRLDRDTSGLMVFAKHGLAHSLLDQQLHSQDFVKQYVAIVtaQTPLATHGWIVLPIGVSDGFYMRRVVTD--TGKASVTEYRTLDQNKAG-----------AMMLVTLHTGRTHQIRVHFAAIGHALYGDGLYSP--------DTHGFNRQALHCAHLRFWQPLKHKLIDLHAPLPADMATLAAKL--------------------------
>UniRef50_B1C3D3(92-300:310) Pseudouridine synthase n=1 Tax=Clostridium spiroforme DSM 1552 RepID=B1C3D3_9FIRM  E=2e-42 s/c=0.84 id=24% cov=80%
-LSIAYENDFILIVNKPINTTIYPETKKELNTLCNYvanYYLETNQYLLIRHIHRLDKDTTGLVLFCKCPLLQPILDNMMANKLIKRSYIAICKGIIDHDLTINRDIARDRHVNKMRIT---NKGLKAITEIKIIKHDKQ---------KNYTVCKCDLKTGRKHQIRVHLASINHPLLSDPLYGN--------KSKLIDRLALHAYKLEFIHPVTKQQIIVKADLPQDM---------------------------------
>UniRef50_D1PDP7(339-551:556) Pseudouridine synthase n=1 Tax=Prevotella copri DSM 18205 RepID=D1PDP7_9BACT  E=2e-42 s/c=0.82 id=32% cov=77%
-VETLYEDRELAVIYKPEGLLSVPGKDAAQPSVYALMRRKYQEATGPLIVHRLDMATSGLMIIAKTEFAYHRLQKEFLNHRVQKKYVAIVCGKDKESCNRILKEAEGGRGyislpliadflDRPRQMVNREQGKEAITEYEVLERIDDTHLR----------LALYPKTGRTHQLRVHCAHqegLNAPIIGDPLYGNE----------PATRLHLHAEEITFEHPMTGKKMTVT----------------------------------------
>UniRef50_B1Y046(43-254:256) Pseudouridine synthase n=43 Tax=Proteobacteria RepID=B1Y046_LEPCP   E=2e-42 s/c=0.82 id=31% cov=78%
LIDILHHDDSLLVVRKPAGLLSVPGRGEHLQDCVAARVQA--IWPDALIVHRLDMATSGLMVMARGPAAQRALGSAFEHRSVTKQYVAVVAGDVAGDAGSVDLPLCADWPNRPRQKVDAAMGRPSLTHWR---RATPAHEGSTTGDIDRTRLELEPVTGRSHQLRVHLLALGHPILGDTLYAPDAVQRM------APRLLLHASRIALPHPAGG----------------------------------------------
>UniRef50_B4WMC0(81-325:328) Pseudouridine synthase n=1 Tax=Synechococcus sp. PCC 7335 RepID=B4WMC0_9SYNE  E=2e-42 s/c=0.71 id=27% cov=86%
-FDVLYEDEDLWVINKPAGLPVLPSGGFLEHTLLYQLRVRYRDCQSA-PVHRLGRGTSGAMLIAKSHIAKVQLSEQFRKRsanlssnttpntastcTLGKTYRALIAPTTPDQlrdrFICTYPIGKLPHTRLGYIYGHLRDAHSHEKTIGPINSmVSRSEGSVLRRRAHSTLVEITIQTGRPHQIRIHLAAAGYPLLGDPLYSaGGVPDPHGYALPGDCGYHLHAHRLQFAHPRTGQSIAITAPPP------------------------------------
>UniRef50_D0LYX0(92-343:345) Pseudouridine synthase n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LYX0_HALO1  E=6e-42 s/c=0.69 id=29% cov=87%
VLDLLYEDDAIAVVSKPAGLPSHPLRAGERDTLANALVAHYPEcaaigadPREAGLAHRLDIDTSGVLVAARTQKAWHALRAAFGSGAVEKHYLALTFGAPSsgemdvalvQRGRRAHPVFRDDaGFGGFGGRGERGDALPARTTWRIERRF-----------GPACLLLCRAHTGRMHQIRVHLALAGAPIIGDSLYAPAPETlsaaeredlAALSEHPEATRHFLHASAVTIPHPETGRALRIEAPLPEGRAQFLAELSRR-----------------------
>UniRef50_A9BWX6(35-244:245) Pseudouridine synthase n=2 Tax=Comamonadaceae RepID=A9BWX6_DELAS   E=6e-42 s/c=0.82 id=32% cov=79%
----LYEDAELLVLDKPSGLLCVPGRGPDKQDCLSGRALQRW--PDALVVHRLDQATSGLVVMARSLASQRLLSEAFAQRRVHKLYVAVVAGRPaaqqaDAWQSIDLPIAADWERRPLRI-IDALQGKPSQTLWRAM------PAATEGHDTPTTRVQLQPVTGRTHQLRVHMAALGHAILGDALYADAAVQA------LSPRLLLHAHQLELAHPLSGQTLRFESAVP------------------------------------
>UniRef50_UPI00016C585E(84-319:324) ribosomal large subunit pseudouridine synthase D n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C585E  E=8e-42 s/c=0.73 id=28% cov=85%
---VRHLDEHVVVVEKPAGVNTvrHPAELEWSEerrelDPTLQDLTQWAVGrqlnrdardlPRLRIVHRLDKETSGLVVFARSALAERELGMQFRKHTVVRRYLTVVPGIL-GTQTIKSNLVPDRGDGRRGSTKLPGVGKEAVTHVTPEERL-----------PGYTLLSCRLETGRTHQIRIHLSEAGHPVCGDKVYCKKANGEVFDDRSGAPRLALHATELGFEHPATSGHLHWTMPLPLDLAKFADRL--------------------------
>UniRef50_A6FXR5(269-508:509) Pseudouridine synthase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6FXR5_9DELT  E=1e-41 s/c=0.72 id=37% cov=78%
---VVYEDDDLLVVDKPPGMLSVPGRGPRRRDSVEYRLkaranpdaieaavaaqskskppagseARTAAGPRLdqlwpRLVHRLDLATSGLLIAAKHREAYVALQRQFSSRQIGKRYVALVRGPLPDalgeGGEIELPLARDLDD-RPRQKVDRREGKVARTRWQLLAH---------EPEHAASRVALYPHTGRTHQLRLHAAHpegLDAPLVGDLLYGYGEGA----------RLMLHAERLTFLHPTRGEPMELRSPCP------------------------------------
>UniRef50_A5ZGG0(358-585:590) Pseudouridine synthase n=4 Tax=Bacteroides RepID=A5ZGG0_9BACE   E=3e-41 s/c=0.75 id=34% cov=76%
-LEIVFEDEWLVVVNKPSGMLSVPGKEEDMDSVYHRLKEKYPDATGPMIVHRLDMATSGLLLVAKTKEVHQHLQAQFENRSIKKRYIALLDGCITETEETTNQTTGNTRKtekvratevisttgkvgrielplcpnplDRPCQSVDEEHGKEAITEYQIITNSE-----------KHTRIAFCPLTGRTHQLRVHAAHpkgLNCPILGDELYGKK-----------ADRLYLHAEYIEFRHPIYGDIICIQ----------------------------------------
>UniRef50_C6JLM4(74-288:289) Pseudouridylate synthase n=2 Tax=Fusobacterium RepID=C6JLM4_FUSVA   E=4e-41 s/c=0.79 id=27% cov=81%
-IKVAYEDKNILLIDKEPYIIVHPTQKKVDKTLangvVNYFLKTTRKIMVPRFYNRLDMNTSGLIIVAKNSYAQSFLQ---EKGIVNKFYKAIVKGIIeKDEFLIDKPIGKVGDDLRRREISVENGGQEAQTKIKVIKRLK-----------DLTLIEAELLTGRTHQIRAHMALEGYPLLGDELYGG--------EDKRAKRQMLHSYKTQFSDIETGELKTVEIDIPDDMKSILSE---------------------------
>UniRef50_B9XQ50(19-266:269) Pseudouridine synthase n=1 Tax=bacterium Ellin514 RepID=B9XQ50_9BACT  E=6e-41 s/c=0.69 id=29% cov=83%
-ISVLYEDEHLLAVDKPSKLLTSPDRYDPKRPNLMKLLHagiergtpwaKSRGLTYLMNAHRLDFETSGVILLAKDKPMLVAVANLFGSEKPVKTYSALVQRSPEEKSFEVDAKLAPHPVKLGLIRVDEKNGKRSRTQFELVEKF-----------AGYSLLKCRPLSGRQHQIRVHLQYAGLPIVGDSLYGgqplmlsslkrDYRLKPNKTERPLLDRVSLHAEELSLVHPLTNAEIKIVAPWPKDLK--------------------------------
>UniRef50_A6GN92(96-309:388) Pseudouridine synthase n=1 Tax=Limnobacter sp. MED105 RepID=A6GN92_9BURK  E=8e-41 s/c=0.79 id=25% cov=78%
-LDIVARTNEYTVVNKQAGLVVHPAPGHWTGTLMNGLYHLDPElihVPRAGIVHRLDADTTGLMVVARTQETQVKLVQMLQARIVKRVYLAMVWGRISSPLTVNNPLGRDPRNRLRMAVVDH--GKPAVTHFTPVAFGELLEV-------PVTLMVCRLETGRTHQIRVHAQHAGFALVADPVYkikgaGSHSALRLSSIELPngekFERQALHATHLSFPDP-------------------------------------------------
>UniRef50_A1AT77(78-305:310) Pseudouridine synthase n=2 Tax=Desulfuromonadales RepID=A1AT77_PELPD  E=1e-40 s/c=0.74 id=35% cov=82%
-LDILYEDDQIAIVNKPSGLAMHRTAEQETNLVEqgTAFMAWRGTPCKLYPVNRLDRGTSGAVILAKSSTAAGIFGRQVKETGLDKLYLALVAGRPDGAGVIDAPL----------------DGKECRTDYRLLAQ-----------GCGFSLLELLPFSGRMHQIRRHLEMIGHPILGDQRYSGRVVEE-------LAGFALHSFRTGLTMP-DGRRLVVCAPLTDELLALCQQGGIEsdSLLPLLKRVALS-----------
>UniRef50_A3U5W9(79-281:283) Pseudouridine synthase n=1 Tax=Croceibacter atlanticus HTCC2559 RepID=A3U5W9_9FLAO  E=1e-40 s/c=0.83 id=29% cov=76%
-LDVLFEDDYVAVINKPAGY---PTSGNFFKTIAKALPYNLKISTKndalliPQPIHRLDNPTSGVLVVAKTKSSQINLNKQLELKGIQKTYIAVVHNTPDSNMLFNDNI----------------DGKESESKLEIIKTFKVKDDI-------YSLVELFPKTGRTHQLRIHTSKAGYPIVGDQLYGISSEKN--------KKLLLHAKSIQFKHPVTGNEVFTTSELPKRFEKLLN----------------------------
>UniRef50_A4S8W7(13-253:264) Predicted protein n=2 Tax=Ostreococcus RepID=A4S8W7_OSTLU   E=3e-40 s/c=0.69 id=33% cov=83%
-LEILHEDEEMTCVNKRAGTASTPESRVADSsaaSLVVARWRRRLVDAHdgalasnvvlgaslvPYVAHRLDLETSGALVVCKNAKAAARAQGAFERREVEKTYLALCrcdefdvSGGGASSGTIDLALAKRDDGARFFVETSSADGKPASTEWTIVAR-----------NRRHALVRCRPKTGRTHQIRVHLAAIGLPIVGDAAYGCLDADV-------VDRHALHAWTLRFPAKdFAGVP-RIVAPVPDDFRRACERVG-------------------------
>UniRef50_C8WX68(72-302:333) Pseudouridine synthase n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WX68_ALIAD  E=3e-40 s/c=0.72 id=28% cov=85%
-LEICYEDDDVIVVNKPAGMLTHPSPHERRGSLLaaAAHYLRDRGGV-PHAVHRLDKYTSGAVLIAKHAHAHHQLDRALRQGLVDRRYVAIVYAPEGCetgrWLTFVDGLAPNPHRPSRRIVVPPDRGDRAVTHALPL-----------VQAGPLALVALVLETGRTHQIRAQMAFHGMPLVGDRDYTYALANRRDPlgqasfYEKAFGRQALHAYALSWPRVEDRAMCKVRARVADDMRELWQ----------------------------
>UniRef50_A4A1L7(9-245:250) Putative 23S rRNA pseudouridine synthase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A4A1L7_9PLAN  E=4e-40 s/c=0.70 id=29% cov=83%
-VDILYEQGPCFCIAKPAGLLTQAPPHIDslESRFKAFIRQRDFktGKVYLGVPHRLDRPVSGVLTFARNVRAARRISQQFETRLVRKLYWAFVAGQPPDDQGVWEDPIRKIPDVAMAEIVspSDPGARWAKLKYEVLQRTEQG-----------AWLEIELDTGRYHQIRVQCASRGFPILGDVSYGGEIPFGPQSEDERARHIALHARYLRLKHPMVDEIVAVTAPLPESW---------------------------------
>UniRef50_A5G5P6(78-280:296) Pseudouridine synthase n=2 Tax=Geobacter RepID=A5G5P6_GEOUR   E=5e-40 s/c=0.82 id=32% cov=77%
-LDILHEDQWIMIFNKAPGLPMHHAAEVDERNLVDlgtkLLAGRDGGSVKLRPVNRLDRGTSGAVILAKSSMAAAMFGRLIMDEGLGKLYLALVEGELAEDGVISVPL----------------EGKEAETRYRVL-----------FHRSDCTFVAVYPVTGRMHQIRQHFKFIGHPIRGDRRYGGQPL-------PGFAGNALHSFRTSIVHPATGETLQVFAPLSKEFLTLLKNL--------------------------
>UniRef50_C0R043(2-211:217) Pseudouridine synthase n=2 Tax=Brachyspira RepID=C0R043_BRAHW   E=6e-40 s/c=0.79 id=30% cov=74%
---IIYEDNYFIAIDKEAGIEV-------DDNLINIIKKEYSHIDNLYLVHRIDKFTSGIVILARDEETKKYFEDAFKNKTINKVYHAIVNGKVKKeNGTIDISIGIDKKNPNRRIPlSIKEGGESAITHYKVLKRL-----------NEHTLLELKPLTGRTHQIRVHLSYIGHPIIGDKIYSK------NADIYKMKGFALIAKEIHFVHPFTKKDIDI-----------------------------------------
>UniRef50_C2G4G7(18-242:247) Pseudouridine synthase n=2 Tax=Sphingobacterium spiritivorum RepID=C2G4G7_9SPHI  E=6e-40 s/c=0.74 id=26% cov=82%
---IIHEDENIIVINKPPFIASL---DEREGGEVNILRLAKKYYADAQICHRLDKETSGILLIAKNPETYRLISIEFEKRRVDKTYHAIIEGTHIFQDLKIDLPILNQGN--KNVTIDRYNGKPAETIFNSIQYFK-----------HFTLVECKPITGRMHQIRIHLATQHAAIVGDSMYRGKPVYLSQIKKRGFtlskdeeeqpimKRFALHSKKVRFK--VADKSYEFEAEYPKDFAILLKQL--------------------------
>UniRef50_Q8EX37(82-294:301) Pseudouridine synthase n=1 Tax=Mycoplasma penetrans RepID=Q8EX37_MYCPE  E=1e-39 s/c=0.77 id=25% cov=66%
ILNVIYEDKNIIVVNKPRGLICQPDKNEKIDTLNNrikkyLYEKKDKNYLEANLCHRLDKYTTGLCVAAKNQKTLTELNNLWNTEAVSKYYLCLCYGKFKKKsDTLKDFIFLNEEKQIMEIDRENKFNKEIITKYRVIEQKK-----------DMALLEIQLLTGKKHQIRVHMASIGHPVLGDTKY-------------------------------------------------------------------------------
>UniRef50_D1ASB1(90-296:299) Pseudouridine synthase n=1 Tax=Anaplasma centrale str. Israel RepID=D1ASB1_ANACI  E=2e-39 s/c=0.79 id=30% cov=80%
--NILYEDQNVIAINKPAGVSVQGGSKVGVSIGDLLDKIRPGG--CCRIVHRLDKDTSGVLVLARDLDVARCLAREFRERRVQKEYIAITKGVPhSASGEVNTPIFYKVQSATGERMLE----KDAKTFFSVTRVL-----------GNFAVVLLRPVTGRKHQLRIHMSQIGCPIVGDSKYCKCGPVEKET-------LHLHASLLTFE--LMGRKLSISAGMPGYMEEKINTL--------------------------
>UniRef50_C1N7S8(37-318:360) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N7S8_9CHLO  E=4e-39 s/c=0.58 id=28% cov=98%
-LTVLYEDEHVLAVDKPPGVMTYPAHRLRGGSVVNRAVHHLRGvtrdgsgggagfgfgaATEPIAVHRLDLETSGVLMLAKDKPSASALQGAFERREARKTYLAVCA-ILEDAANASDESDDDFDFERHPGHRRRERRRRAVHTRGDAGREAREHRFTGKRIVGTALVLARPLTGRTHQVRLHLAHAGLPIVGDALYGYDDALRPASGGFE-GRMALHAWNLAVKHPRTKNTMRLAVDMPADMQALSVGLGLRvegvllgdaaaaaAAAGAAKRTSTSARTGSDG----
>UniRef50_D2R6S8(7-224:230) Pseudouridine synthase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R6S8_9PLAN  E=7e-39 s/c=0.75 id=33% cov=80%
-LDILHEDNHLLVINKRPLLATQGVAEGTPSLVTEVQQylkvkYKKPGNVYVGVVSRLDAHTSGVVVLARTSKAASRLAEQFREQGVEKTYWAAVEAAPEPASGELVSWVVKDDKNRRMTIADRKlaGCQKAVLTYETLEQNKS-----------AALVSVKLETGRKHQIRLQLAdELSLPVIGDRKYGSRIEFPEG--------IALHARELAFDHPVGGKRLSFVAPLPATWK--------------------------------
>UniRef50_A9DVX4(4-214:224) Pseudouridine synthase n=3 Tax=Flavobacteriaceae RepID=A9DVX4_9FLAO   E=8e-39 s/c=0.77 id=30% cov=80%
-LEIIHENKDYIVVNKASGLISEKSPYEavTVEDQVFQHILKSKRKPYVGIIHRLDRVTSGVLILAKKKSILVAFNKLFSSRKVQKTYLAIVKNKPTKSKGNlvNFLIKNNKEKKAEIVTTKSKEAQSCMLSYEVIGKNNIGY-----------LLAVKPKTGRFHQIRAQLANIGLPIVGDSKYGSDVSYKSLS-------ICLHAWKLTFEDVETKEQKTFEASLPNH----------------------------------
>UniRef50_Q12RE8(386-593:593) Pseudouridine synthase n=83 Tax=Bacteria RepID=Q12RE8_SHEDO   E=1e-38 s/c=0.78 id=32% cov=78%
-ITVIYQDEHLLVISKPAEFLSVPGKNISDSVHTRI-IRDFPSASGPIIVHRLDMSTSGLMVIALNKEAHESLQKQFILRTVTKRYIALLDGLLPNRTAGDEGIIslplRGDLDDRPRQLVCHEHGKSAETRWQIID-----------IQQGRTKVFLYPKTGRTHQLRVHCAHsqgLHLPIVGDDHYGVR-----------ASRLHLHAESLSFTHPQSREALHFQ--LDADF---------------------------------
>UniRef50_D1B0V0(70-288:302) Pseudouridine synthase n=1 Tax=Sulfurospirillum deleyianum DSM 6946 RepID=D1B0V0_SULD5  E=3e-38 s/c=0.73 id=31% cov=76%
-LRPIFETEDFAVFDKPSGVMIHPRKRSDGYTLN--DEIKSLYGKDANAAHRIDKSTSGLVLVGKHKQSEIALKEIFATRKVQKSYIALVKGHLKEELLIDEKLKRDVETSQIRLKVhVDERGKPSQTKVIPLHYFE---------DKDATLVQAFPYTGRQHQIRVHLFHVKHPIVGDMIYGVEEEDAERyldgsmsaeeqYEKTLSSRLLLHAYSLSF----------------------------------------------------
>UniRef50_D1QMM7(322-518:522) Pseudouridine synthase n=1 Tax=Prevotella oris F0302 RepID=D1QMM7_9BACT  E=1e-37 s/c=0.81 id=35% cov=75%
-LEWIYEDKDIVVVCKPAGMLSVPGKSLRENVRSLVRQ-RHPEATGPMIVHRLDMATSGLLVVALNLKSYIDLQRQFEEHSVQKRYVALLSRPHHGARSGQISLPLRPDlYDRPRQIVDAVHGRKAVTNYQ---------------QTGENRMNLYPLTGRTHQLRMHCAHadgLNNPIKGDELYGTRDE-----------RLYLHAEELSFVHPGTGKRMHFEC---------------------------------------
>UniRef50_C4GB89(92-302:337) Pseudouridine synthase n=1 Tax=Shuttleworthia satelles DSM 14600 RepID=C4GB89_9FIRM  E=2e-37 s/c=0.75 id=34% cov=76%
-VHVIYEDEDILALDKPAGCLSQRAGQKDISLNEEMLAYliakgaltrESYFLFHPSVANRLDRNTSGLILAGKTLRGQQYLSEQLRDRSVIKLYHTIVRGRLTEELQLDGYLYKDVGRNQvlvsEKKEDLPEGAQEIHTAYRPLDHRK-----------DLTLLEVHLMTGRSHQIRAHLASIGHPIAGDPKYGDFHWNQILRRKYGVRGQLLHSYSIKLP---------------------------------------------------
>UniRef50_Q11QN3(10-235:240) Pseudouridylate synthase n=5 Tax=Sphingobacteriales RepID=Q11QN3_CYTH3  E=5e-37 s/c=0.69 id=28% cov=80%
---IIFENDDYFFINKPPFISSL---DERTGGAPSIIRMAKEYWPDAQLCHRIDKETSGVLAVAKNPAAYRHLSMAFESRNVTKEYHAVVNGTHDLDGVDVYLPILVLPTGTVKI--DKSKGKLAETIFFTIQAYK-----------KATLVRCLPITGRMHQIRIHLATLGASIVGDETYGGKPlflseikrkkfnLKKDSEERPLIQRFALHANSLIFTD-MNEQILDIKAPYPKDF---------------------------------
>UniRef50_C1E6N6(130-363:363) Pseudouridine synthase n=2 Tax=Micromonas RepID=C1E6N6_9CHLO   E=6e-37 s/c=0.67 id=27% cov=85%
-FHLVHEDADYAVVNKPWcvrldtprGWPgkVRFTPKYPGDLSVEdWLERRYPDWDTVRFCHQLDNATSGVLVAASNKRAAGAAAKLFRERRARKTYLAIVFGHPEQDeWTVDVPMGRDPDDPKgFRERVDPEHGKACETRFRVLKRGRLNLR-GKFEGVPVSKVEVTPVTGRRHQIRLHLQFSGHPIVGDNAYSQDTDSF---------RTFLHAHKLTlpFDEPRG--TMQFVAPEPESFAAAME----------------------------
>UniRef50_B9DIP6(75-293:294) Pseudouridine synthase n=61 Tax=Staphylococcus RepID=B9DIP6_STACT   E=6e-37 s/c=0.71 id=29% cov=75%
-IDVLFEDQYFIAVSKGKKQNCAPSREHPHGSLIeqVIGYLKDQAADGnyqsiPHIVTRLDRDTSGIVLFAK----HGHLHHRMSSTEMKKVYHCICNGKLENTSKIVAPIMRAGDSIIER--KVDQAGKYAATSYQPI-----------NASEQYTLCEVRLHTGRTHQIRVHFQYINHPIVGDGLYGGL--------HTFVTGQALACCYLSFKHPITHEQIEL-----------------------------------------
>UniRef50_A3DGV1(83-290:320) Pseudouridine synthase, RluA family n=3 Tax=Clostridium thermocellum RepID=A3DGV1_CLOTH  E=8e-37 s/c=0.75 id=28% cov=76%
-FSVAYEDSNLLIVNKKQGIPVHPDRTQTENTLIdfvkeylkLKGEFEENSGFTPSLCHRLDRNTGGLVMIAKNSSTLHMVLKKMKSGEISKYYQCLVKGKME-KKEDILKAYLEKDEKKSRVFIKDTKSKNAVeiiTGYKVLSYKELPDI-----GEGISNLEVTLYTGRTHQIRAHLAHIGHPVVGDGKYGINTFNRL----LGAKYQALWAYKLKF----------------------------------------------------
>UniRef50_B4D302(76-288:289) Pseudouridine synthase n=1 Tax=Chthoniobacter flavus Ellin428 RepID=B4D302_9BACT  E=1e-36 s/c=0.73 id=29% cov=80%
-IRICFEDAALLVIDKPPDLLTIASEAEQEKTvyfqLTEYLRGNDvHSRERVWIVHRLDRETSGIMVFAKTPQAKGLLQTGW--DKAEKRYQAVIEGSLPNDKGTFRSYLDETDPFRVISVPRTPTTRHAVTHYRVLKR-----------GKGRTLVELTLETGRRHQIRVHLADAGCPIVGDKKYGAKTNPAKRLGLHSWSLLL--------LHPISGEEHRFESELPTDLARL------------------------------
>UniRef50_Q9ZMA1(72-292:293) Uncharacterized RNA pseudouridine synthase jhp_0321 n=14 Tax=Helicobacter RepID=Y347_HELPJ  E=3e-36 s/c=0.70 id=27% cov=82%
----VFEAKDFGVFDKPAQIYTHPKGYFYHESL--LDCIQSHFGKNAHPAHRLDYETSGLVLAGKTLQSTKDLKALFMQKKVKKTYLALAHGLVDKSIIINKPILTpqNIQKDLRIRSQISPLGKPSITLVEPLSY---------NPFLDISLLKITPLTGRTHQIRLHLSSVDHRIVGEGLYGVADENA--REYLQLKRennaptLMLHAASLEFE--FKGAHYKIASPMPERFMPFLK----------------------------
>UniRef50_A8EQU7(71-279:300) Pseudouridine synthase n=2 Tax=Proteobacteria RepID=A8EQU7_ARCB4   E=4e-36 s/c=0.73 id=28% cov=76%
-LKPLLEFEDFAIFDKPTNLMVHPISKNT--SYSLLDEIRYHFGENANLIHRIDAETSGLVIVGKNKKSEIELKDMFQEKKYHKSYLAIVQGEIKEELKINKALDREGKaiGVRMKVCTQEEGGKESITIIKPI---------IYDKEKNLTLVEALPLTGRQHQIRVHLHSMGHTILGDPIYGVDDENAENYLNKTLSeedrfkvtksyRLWLHANYLEF----------------------------------------------------
>UniRef50_C1EDH6(65-322:345) Predicted protein n=2 Tax=Micromonas RepID=C1EDH6_9CHLO   E=4e-36 s/c=0.59 id=22% cov=91%
---VIHEDDDVLVIDKPAGMSFHNDDlvTNLPGVLSTVRALQAKGELRgsdyageLHSVHRLDKITSGILLLAKNERVASWLARQFARRRVHKYYVALSARKPSKKMGTVRGDMAQARRGTYKLTRCSSNSTPaAVTKF----VSRGVRGASPGGDRPLRVLLMRPLTGKTHQLRVCAKSLGAPVLGDAAYGGADTNKNANKNDGAggeDRGYLHAAALRVAMP-GGNVMEVVCKPTEgrewthasaGFHDAWTSFGFDELIGADE----------------
>UniRef50_A4XK98(79-268:311) Pseudouridine synthase n=2 Tax=Clostridia RepID=A4XK98_CALS8   E=4e-36 s/c=0.81 id=28% cov=73%
----VYEDDNIIVIDKPYGIPSHPDTNNEY-SVVNWIEDNYSGNQLPALCHRLDRNTSGLMIIAKNRQVLNEMLKYMSRRAIKKKYLCITKKVdLPKSGVLVHYLKKDSKKSKVYISDlPAEGYSEIVTRYKIIR-----------GKDDLLLVDVEIETGKTHQIRSQLAHVGLCILGDSKYGDWALNKKYNASI----QCLCAYYLKF----------------------------------------------------
>UniRef50_Q3A211(78-293:296) 23S RNA-specific pseudouridylate synthase n=1 Tax=Pelobacter carbinolicus DSM 2380 RepID=Q3A211_PELCD  E=6e-36 s/c=0.71 id=26% cov=82%
-LTILLETDEFLAVFKPAGLAVHSSVGHTEDNLTDRLKAwikQCKAPYRIAPVHRLDIGTSGPVIFGKGRKATAELGRLLQNGHMSKTYLALVNGHPPETGMMVT------------SVRVQGKPKQAATRFRVLGRHASAALLELELLSG-----------RKHQIRQQCADAGWPLYGDHRYGGP-------ELPGRDRLFLHCWQLAWPIQGDQPSHRITSPLPEELSVILTSMDIESPAPNRK----------------
>UniRef50_D1B8F2(87-298:302) Pseudouridine synthase n=1 Tax=Thermanaerovibrio acidaminovorans DSM 6589 RepID=D1B8F2_THEAS  E=1e-35 s/c=0.72 id=35% cov=79%
---VIHWDRRLLVANKPAGWICQPGGGRGTSLPEEVWRL-LGVDRGPVPSHRLDVNTTGVVLVPLDGALGRELHRLFREGTIRKLYWALVRGTCVGEALVDLPLSKD----GRGNVTPSPSGQPARSVVRPLAVR-----------GGFSLVEVELLTGRQHQARVHLAHLGLPILGDVRYGVRF--------RGVGRTMLHARRVLLPF---GESLgdlagaAFEAPLYPDMAEAARRLG-------------------------
>UniRef50_Q09709(107-286:394) Uncharacterized protein C18B11.02c n=1 Tax=Schizosaccharomyces pombe RepID=YA32_SCHPO  E=2e-35 s/c=0.84 id=26% cov=66%
---IVHEDESYVVIDKPAGVPVHPTGRYNHNTVLHILMKENKCSL-LYPCNRLDRLTSGLMFFSKSPKAAEEMRVHMISKSLKKEYVARVIGEFPNSGEVICDAPLLTVAPTLGLNRIHPDGKEASTVFKRIA-----------FDGHTSLVLCKPLTGRTHQLRVHLQYLGYPIANDPIYANKR---------------------------------------------------------------------------
>UniRef50_A8SBU6(2-228:231) Putative uncharacterized protein n=1 Tax=Faecalibacterium prausnitzii M21/2 RepID=A8SBU6_9FIRM  E=3e-35 s/c=0.66 id=32% cov=78%
---ILYEDAALVVLDKPAGLSS------EEGVPAALRAHWNAPDAFVGVVHRLDTGVSGLMVYARTPAAAAALSRQVtqsqdayavqdgraegkaAAPQFVKQYRAIIAGAPdaqlPAAGVLRDYLFKDSRKGRVFPVsRPRKGVREAVLEYRILAT-----------AGENSLAEITLHTGRTHQIRVQFASRRHPLYGDGKYGSRQKGS----------IALQSCGLRFVHPDTGKPMAFSLPLPAAapWKEFLE----------------------------
>UniRef50_C5M016(1-259:417) tRNA pseudouridine synthase C, putative n=3 Tax=Perkinsus marinus ATCC 50983 RepID=C5M016_9ALVE  E=3e-35 s/c=0.58 id=25% cov=91%
-----------MVVYKPAFYRCQLPDDHPEDSIVSWLSRQYEIDPELMneelnpalsggggfgpMCHRLDKQTSGPVLIARKLESWKFIRRQFQKEQVTKRYVCLVDGICANDSGMIDSPIRVRRTEKHTSAEIGSGPAssSAHSEYRVLERYEE----------GCTLMSVRITTGVTHQIRVHMAQgLGHPIVGDKKYTPSGRGSELPCATRMPgRVFLHCYELGVkPDKTSGQKLtTIKCSLPTELRNLLWSLTPIStcPLPADTRALLAGLMGLPS----
>UniRef50_Q57Z98(600-825:828) Putative uncharacterized protein n=3 Tax=Trypanosoma RepID=Q57Z98_9TRYP  E=8e-35 s/c=0.66 id=32% cov=80%
IFPVVYEDDDLLVINKPPHVATsrhalscsQLCDDKATDIVSLQLTCKKRGDvmrrvFRQGQVHRLDTETSGCLIMAKSDVAASSLRHQMgtsaAYSQSSKIYLALCAVVES-----------NLTNIPLNGVLRDPADAKITTKYRIV---------HFYKRFRVALVEARIQQGKKHQIRRHLAAVGLPILQDVEHGGAACCSP-----LLQRVALHASSVTVVHPRTAEVLTCVAPLPEDMRSAI-----------------------------
>UniRef50_A7RMP5(88-274:418) Predicted protein (Fragment) n=2 Tax=Metazoa RepID=A7RMP5_NEMVE   E=1e-34 s/c=0.80 id=31% cov=64%
-LEIICNTDDIVVLNKPSSIPVHPCGRYRHNT-VVFLLGKEHNLRNLYTIHRIDRLTSGILMFAKTLTRARMLEAQVRDRQVEKEYLCRVQGEFPSEPVdCEQPIIVVSHKVG--ICRVSPDGKSCRTVFTKL-----------HSNGKSSVVKCIPYTGRMHQIRVHLQWLGYPIIDDPIY-------------------------------------------------------------------------------
>UniRef50_B0RMG5(110-311:319) Pseudouridine synthase n=4 Tax=Gammaproteobacteria RepID=B0RMG5_XANCB  E=1e-34 s/c=0.74 id=28% cov=78%
---VVHADGQIVVACKPHFLPVVPAGAYVRETL-LARLVRRFDNPSLVPLHRIDRDTAGLVLFSANPATRGIYQALFRERRIHKHYLAVAP-PLPALTFPYVHRSRLEPGEPFFRMREGVGEPNSETVIDVVAR-----------GADMWTYRLEPVTGRKHQLRVHMAALGVPILHDRFYPELEDQRPDDPERPLQ---LFAHMLAFDDPITGEPRRFTA---------------------------------------
>UniRef50_A9UX27(112-295:401) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UX27_MONBE   E=1e-34 s/c=0.80 id=27% cov=65%
-LSIVGETPDLLAIDKPASIPVHPCGRYRHNT-VQAILGHEHDRWRVYPCHRLDRLTSGLLIFCKNPAMAKQFEQWITQHQVEKQYICRVQGRVEQSVLFCDAPLKICD-QRLGLCCVHPEGKASLTRFRVIRR-----------DKDTTVLHCFPKTGRMHQIRVHVQYLGHPIVNDPVY-------------------------------------------------------------------------------
>UniRef50_A6BI61(41-290:296) Pseudouridine synthase n=4 Tax=Clostridiales RepID=A6BI61_9FIRM   E=1e-34 s/c=0.59 id=25% cov=83%
-LNILYEDPHILVCVKPHGIATQSKSiRYPDMVSLIKNHLAKASGtsgksgapksigsrtpgsaePYLAVIHRLDQPVAGILVFAKTPAAAKDLNKQLQNQGFGKYYRALVTNAPsEEEGTLEDYMVKDARTNTSRICSAKENGaKIARLHYDTVpdhgrlfstvsgsSSSVDVSLSSQSQECHETELEIHLDTGRHHQIRVQLASIGCPIVGDTKY-----NPELTGNKGWQTIRLCAYKLDFKHPVTHKAMHFQ----------------------------------------
>UniRef50_C4G2Q7(5-224:236) Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4G2Q7_ABIDE  E=2e-34 s/c=0.67 id=28% cov=77%
-IPILYEDEDIIVCVKPVGILSQ---GDKDGNKDLVRELKKHLvisarknkqsigkEPYIAVVHRLDRNVRGIMVYAKTGRAAAGLSKQIAENKLTKRYMAVVSFTPERCTPEINVEKKRIDyiaadkvkNISTIAEKESKGAERAELNYKVIKT-----------AGNKALVQVDLITGRHHQIRLQLSQIFNGIVGDTKYNDDYKLTDGWKDP-----ALEAVELSFVHPVSGEKLSF-----------------------------------------
>UniRef50_A1KNV2(85-285:305) Pseudouridine synthase n=13 Tax=Mycobacterium tuberculosis complex RepID=A1KNV2_MYCBP  E=3e-34 s/c=0.73 id=28% cov=77%
-VPVLHQDADIVVVDKPHFLATMPRGRHVAQTALV-RLRRELGLPELSPAHRLDRLTAGVLLFTTRREVRGSYQTMFARGLVRKTYLARAP-VAPGLALPRLVRSRIVKRRGHLQAVCEPGVPNAETLVERIARDG--------------LYRLTPTTGRTHQLRVHMAALGIPIMGDPLYPN---VISVAAHDFSTPLQLLAQRIEFDDPLTGSHREF-----------------------------------------
>UniRef50_A7K4M8(14-212:243) Pseudouridine synthase n=47 Tax=Gammaproteobacteria RepID=A7K4M8_VIBSE  E=5e-34 s/c=0.73 id=28% cov=71%
MFDILHTHPDFLIINKHPNVSVH---KDDGDTMLLQEVAKQSGDEQLYLIHRLDKMTSGILFLGRNAKAASALSQAFADRQVEKFYLAIGSKKPKKKQGLVVGDMERSRRSSWKLVNSKNN--PAVTQFFSLA-----------AEPGERLFLCKPHTGKTHQIRVALKSVGSGIVGDPIYNAGNE---------ADRGYLHAFSLCF----------------------------------------------------
>UniRef50_UPI00006CD8DD(102-282:446) pseudouridine synthase, RluD subfamily protein n=1 Tax=Tetrahymena thermophila RepID=UPI00006CD8DD  E=5e-34 s/c=0.81 id=28% cov=66%
---VIFEDDKLLVLSKPPYISVHASGGFHFNSLVGLLKFEMGYNIELYVLHRLDKLTSGVLIMAKDRDLTKKFHES-ETELIKKTYLARVHGNFNHQYlEYEKPIYCIYKKVGTYAVLDttdeeeikSKGAKQSKTIFKKIWYDE---------KSDSSLLECQPITGRTHQIRVHLSSLGFPIINDTQYGG-----------------------------------------------------------------------------
>UniRef50_A9G6K6(475-703:765) RNA methyltransferase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9G6K6_SORC5  E=6e-34 s/c=0.64 id=26% cov=85%
---VIYDDDGVLVVEKGPHEPV-ATQPEYLGSLLARCARIPGSTTTPIIVHPLDPGTSGLVMLARSEEAAARWGEALAKTG-RLIYLAAAKGVTPGKG----AITRDLREGTRTY--------TARTRYRRLAV-----------ASGHSILRVIPDGGRTHQIRRHLAAIGHPILGDERYGHVPTNRYFEEKHGLDRSFVHLVRIEIEHPRTGVKMIIESTLPGDLRSALERstgpsvlrfLEQKHALGEQRAVP-------------
>UniRef50_B8C2A6(273-595:596) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8C2A6_THAPS  E=7e-34 s/c=0.45 id=32% cov=82%
-LQTIYFDKDIVVTNKPSGLLCVPGVNHYRSLLDLVYEvyggganpndkgisttqqttdesatttLEEPLQKDSMIAHRLDMDTSGIVVFARTRLAMSKLHKSFRERTgTRKRYEALLVGWLDTatwassannssnnnylgcnagdttadtdlgGGEINLPLQRDHKHPPFMRVSTPESeveaamavrdlnhagwkklvakrPKPSTTQFRILAH-------EVWMDHPITRVELTPITGRTHQLRVHCAAIGHPILGDPAYGwcgeahpnggfceeVMRQMSPTCAGMELQRdveesvqasgrtMCLHARRLGFHHPATDKYVEFEA---------------------------------------
>UniRef50_D2NPM0(136-369:377) Pseudouridylate synthase n=2 Tax=Rothia mucilaginosa RepID=D2NPM0_9MICC  E=8e-34 s/c=0.62 id=28% cov=83%
--PVLYEDEHVLAIDKPHFLPTTPRGAYIAQTALTKLRVREQ-NPLLIPIHRLDRPTAGVLLFAKTVEARRPFQMMFQHRRVSKTYRAVAPvpadpaaaeRALSAEGLQVRSHIQKIRDQLQVQQLSEEQCaaqgvePNTLTTAKILQTFTPSaqavEGWRAEPNREWALYDLAPHTGKTHQLRAHLNMLGSPILGDVLYPQVLPDAPDRPEYPLQ---LLAYSLHFEHPITGERVDLYS---------------------------------------
>UniRef50_Q4PCI6(57-240:1096) Putative uncharacterized protein n=1 Tax=Ustilago maydis RepID=Q4PCI6_USTMA  E=1e-33 s/c=0.79 id=26% cov=66%
-IKIIHRDDDegILVIVKPGSIPVHAAGRYLRHTLVGLLQSEHGVD-MVYTTNRLDRLTSGIMVCSTKKETASRLGAQFAAGQVNKAYVCRVRGKFPQGEVVCKQPILTIDRQ-SGVNIVHPKGKHCETIFVRLSY---------DASDDSSVVFCRPITGRTHQIRVHVQYLGHPICNDPIYG------------------------------------------------------------------------------
>UniRef50_C0QI10(85-289:298) Pseudouridine synthase n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QI10_DESAH  E=2e-33 s/c=0.71 id=25% cov=79%
--EILFHNDHLIAACKPHFLPVVPSGPHVNETLLNRLKIRFS-NPDIVPIHRLDRETAGVVLFSVEPETRGAFQHLFMEKKVKKTYEAVTRRPGTLPHLPSVIVNRIERGEPWFRNTIVPGRPNAETRLELV-----------GADRDRAFFRLYPQTGKKHQLRLHLASLGFPIENDRCYPDLLPKQGDDWEHP---LMLLSREVRFMDPIAGRERVFTSP--------------------------------------
>UniRef50_D1AYL9(88-268:280) Pseudouridine synthase n=1 Tax=Streptobacillus moniliformis DSM 12112 RepID=D1AYL9_STRM9  E=7e-33 s/c=0.79 id=29% cov=64%
---IVFEDEDVFIINKPNNMPMHKGDKHKFGLSETAKAY--YNNPNVNFANRLDLETEGLVIGCKNLQILRKVNEEIRNKKIIKRYIAKVEQ--KKLQLDEEFFSDKKIKIFEDRVRVSKDGLEAKTYFKVIEVKDFKV-----------LLDIELITGRKHQIRVHLSDIGHPIIGDSKYGN-----------------------------------------------------------------------------
>UniRef50_A4QI08(95-315:322) Pseudouridine synthase n=5 Tax=Corynebacterium RepID=A4QI08_CORGB   E=1e-32 s/c=0.64 id=24% cov=83%
-IHVIHEDDDILVIDKPPYLATMPRGRHITETALVKMRVLTGNN-DLTPAHRLDRLTSGVLVMVKKPELRGAYQTLFARREASKTYEAIAEFVPGlLDNGPAIWESRIEKERGIVQAFVVEGPVNARTELVSVTPVDDAEQSIleemHGPLPRQARYVLAPSTGKTHQLRIHMRDFAAPILGDPLYPVLHAVDDEDYTTP---MHLIARTLTFVDPQTNEERTFVS---------------------------------------
>UniRef50_Q54UF9(240-441:578) Pseudouridine synthase family protein n=1 Tax=Dictyostelium discoideum RepID=Q54UF9_DICDI  E=5e-32 s/c=0.69 id=29% cov=66%
-IKIVSLDENVVVVDKPSSIPVHPCGRFRHNSL-MYILASEHGINQLYGVHRLDRLTSGLLLLARTPDSANKKANQIQSGLVSKQYLAKVIGKFPgsdtinsssssfneqiklckhlEDGTFIIDQPIVIQSMRLGINHVGVGGKPSITHIKLFSY---------DQSTNTSIVLCTPKTGRTHQIRVHLKWLGFPIANDPLY-------------------------------------------------------------------------------
>UniRef50_C7LQ47(92-276:281) Pseudouridine synthase n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LQ47_DESBD  E=1e-31 s/c=0.75 id=29% cov=67%
------------VWNKPAAVLSQGTRFADHCTLPRLAQAKLGSRNELHPVHRLDREARGIMLLAHDGKAAAKLGELFRQGAVVKEYAAIVRGIPDWTDIE---------------VNEPLDGKEARSRFHVVQS---------DPASDMTLLLARIDTGRKHQIRRHLNGLGHPVMGDPRYGRGTRQVQE--------LQLVARSLAFTCPFTNAP--------------------------------------------
>UniRef50_B5Y592(1-175:175) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B5Y592_PHATR  E=1e-31 s/c=0.79 id=28% cov=67%
-LKIVHEDEHIIVVDKPSGVLTVPSDKNVPSLaqAVFDHCQPTEVTLDQMVVHRLGMDTSGLIVLAKTMDTVRQMNALFRTRKITRQYEALVVGHLPQHGGLISLPLMRDYEHPPYMRKLLEMPKESLTKYEVVNREDM-------DGTPVSRVALTSISGRTHQLNVHLAAFGHPIVGDSVY-------------------------------------------------------------------------------
>UniRef50_Q0S710(127-330:338) Pseudouridine synthase n=31 Tax=Bacteria RepID=Q0S710_RHOSR   E=1e-31 s/c=0.68 id=28% cov=78%
-IEILHRDEDLLVVDKPHFLASTPRGAYVAESALV-RLRRDFDLPELTPAHRLDRLTAGVLIFTVRREVRRDYQSLFDQRRVVKEYEAVARYDPDLRLPATVRSRIVKERGVLKAY-EMDGPANSESRIELLE-----------IHGDAARYRLLPHTGKTHQLRLHMSSLGIPIHGDNFYPDFYDVAADDYSTPLR---LLARSVEFVDPYSGVTRRF-----------------------------------------
>UniRef50_A4CVN5(20-213:215) Pseudouridine synthase n=1 Tax=Synechococcus sp. WH 7805 RepID=A4CVN5_SYNPV  E=2e-31 s/c=0.71 id=30% cov=74%
----------LMVVDKPAGLLCQPGlGSHQQDSLISRLQLAC---PALRLVHRLDRDTSGLVLLAKDPDMLRLLGMFFASRRVRKLYVADVQGQMKNVSGLIGLPLARLKRQPPTYGV-HPGGKACVTLWRRLKLMESS-----------TRLWLCPRTGRSHQLRAHLAALHHPIIGDPIYNPGCAV----------GLRLRAMALRFPDPDdpSGQ-VRVRAPWPAWF---------------------------------
>UniRef50_Q31EX3(98-295:300) Pseudouridine synthase Rlu family protein n=1 Tax=Thiomicrospira crunogena XCL-2 RepID=Q31EX3_THICR  E=2e-31 s/c=0.70 id=30% cov=61%
--PVLIEDaDDFSVWYKPKGVLSQGSKWGDHTTLnrwieTHYLFKEPPEKRPCWIVHRLDKATDGLILIAHNKKSAQMLARRFEAHQIGKSYQAWVKGKF---------------GETERVFDQDVNGKTALSKAHQL---------VYNSDNDCSLVQVTIATGRKHQIRIHLSKAGFPIIGDRLYGD-----------------------------------------------------------------------------
>UniRef50_B0E0Y2(98-341:478) Predicted protein n=2 Tax=Agaricales RepID=B0E0Y2_LACBS   E=1e-30 s/c=0.55 id=31% cov=67%
-VKVLYHDveREFLVVDKPGSIPVHASGRYYRNTLIEI-LVNDFGYKKCYPANRLDRLTSGLMIIPLSPDRARVLTDEFTTGTVRKEYVARVRGRFPAQEIVCEEPLLTVDRQMGLNIVHPEGKvlfihlQPAKTVFNLIRYDE---------NTNSSVVRCEPLTGRSHQLRVHLQYLGFPIANDPIYSESR---------------------------------------------------------------------------
>UniRef50_A9RVX3(69-264:361) Predicted protein n=1 Tax=Physcomitrella patens subsp. patens RepID=A9RVX3_PHYPA  E=1e-30 s/c=0.69 id=34% cov=72%
----LYEDQYIIGVSKPGTLLVHnnkassPLEKQRNAFLKNMVEAQLTAGQKVSPVHRLDRPASGAIIFSKSAVATRAAQASLSHPACIKEYVVLARGTTPDFFICDEP-----------VNDEKGAPKSAVSQCEKI---------LDLPESRCSLLKVVIKTGRWHQIRKHLNHRAHHVVGDVKHGKGKTNRFFRENHKMlsGRIFLHAARLTFPHP-------------------------------------------------
>UniRef50_Q9LU60(132-327:395) RNA pseudourine synthase 7 n=12 Tax=Embryophyta RepID=PUS7_ARATH   E=4e-30 s/c=0.68 id=31% cov=65%
MIDdvvILHQEPDVVTVCKPASVPVHPCGQYRKNTIVGILDAEHDLGT-LFPIHRLDRLVSGLLIIARTAAKADFFRQQIEGGMVKKRYIAKVIGVFPEDEMIVDANINYNGSEGRSTAedanssgdDKKVKGKPACTKFTRIDT-----------NGTHSLVSCEPVTGRTHQIRVHLQYTGHPIANDPLY-------------------------------------------------------------------------------
>UniRef50_C1E8M2(30-241:279) Predicted protein n=2 Tax=Micromonas RepID=C1E8M2_9CHLO   E=4e-30 s/c=0.63 id=29% cov=68%
-LEVAHEDAHFAVVVKPEGVNTVGdARGGWTAERMLPYFLAPTIGvegalVRPRPVHRLDALTSGLLVVAKTRLAATSLSEAFASRRVTKRYRAVLCGTPAEPEVLVDDDDDDENDRagaaalKLGVIDAPMEGKQCVSHWRVVR----DAPDASMRHGRLTLVDMWPKTGRTHQLRRHAAgALGCPILGDARY-------------------------------------------------------------------------------
>UniRef50_C7RAZ2(84-301:305) Pseudouridine synthase n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7RAZ2_KANKD  E=4e-30 s/c=0.61 id=23% cov=83%
---IIEHNEHFLIAYKPHFLPVMPGGVFVNECL-QQRLIDKTGNPNLQAVHRLDRDTAGLVMFSTNPHTRSDYHQLFAQQNIKKHYQAIAKTQAGESLSGKSWHIKNylARSEPQFIFQNLDTSPDDTSPHDKDAQYAESLIHCEDDNLQLGLFTLSPITGRTHQLRLHMMSLGFPILNDRFYPSLQPKQADNFSQPLQ---LLAHKLSFIDPVSKEPRAFTSPV-------------------------------------
>UniRef50_D0WNY8(101-305:306) RNA pseudouridylate synthase family protein n=1 Tax=Actinomyces sp. oral taxon 848 str. F0332 RepID=D0WNY8_9ACTO  E=8e-30 s/c=0.65 id=30% cov=74%
-LDVVDGTDRWIAVDKPAGMATMPRGKHVAQTVTIA-ARRHFSNPEIVAAHRLDAATRGVLLLTLAKRWRAPYQMLFERREVRKAYLAVAPADDRFVEAQTVALALAKPRGSLKALVVD-GQPNAVTTVRL-----------ADERRGLGLYEIEPKTGRTHQIRVTMSHLGIPIVGDWLYPEVRDGGD---------LQLLAARLEFVDPANG----------------------------------------------
>UniRef50_A9GNR7(140-364:368) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GNR7_SORC5  E=3e-29 s/c=0.58 id=29% cov=73%
-LDVVLERDDLVVVNKPAGVPTAPLHPGERGTVANALVARYPEmagigfsPREPGLCHRLDTDTSGLVLAARTAAAFAALGAGLKEGRLDKRYLLICQiGDLPEMGSIEVPLAPHPKDKKRVYPCIHPrdvaryAPRPAATMYKRVRQVGLWE-----------LVEARAPRALRHQIRAHFASVGHPLAGDVLYGGPAVE-------GLSRHALHAHYIG-----------------------------------------------------
>UniRef50_B7FPM1(1-168:168) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FPM1_PHATR  E=5e-29 s/c=0.77 id=25% cov=64%
-------DAAVYVCNKPSSVPVHPAGPFLSNSLTIMVEAQVGLQcGSLKPVHRTDRVTSGLTLCCKSSAVARIFHRCLSEGTVDKLYVARVHGKFPsTNSEMHLDAAVHTLDPANGVRIVDSAGKPSKSVFKLVD---------FNQAENVSVIACQPITGRNHQLRVHLQMLGYPIVNDTQYG------------------------------------------------------------------------------
>UniRef50_B5Y415(1-189:193) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B5Y415_PHATR  E=5e-29 s/c=0.69 id=30% cov=67%
----------------------------------------SRTSQSLFIVHRLDCETSGVLLFARTSEAASRLSRAWREReHVQKTYVAKVYSWrlPETSGRIDLALAPHPTERIK--WIASKEGKPSTTLWTVMpdERKATCQNPDSDGCARPVKLRLIPVTGRTHQLRIHCCAHGDGILGDTLYGKFATQSLPGKR---SRLFLHSQALSVPHPTTGKMVTF-----------------------------------------
>UniRef50_O16686(148-326:432) Uncharacterized protein K07E8.7 n=2 Tax=Chromadorea RepID=YK27_CAEEL  E=5e-29 s/c=0.73 id=28% cov=64%
-IRVISETDDLFVVEKPPSLPVHTCGQYAIHTVLGQLRVNEGR-TGLRVLHRLDRATSGVLLFAKNYETDLEFKTTLKQGEWSKEYICKVDGVFPDeEQVCEQPIGPLVISMGIQCVRPD--GKDAKSRFRKLWS-----------DGTQSVVQVHIETGRTHQIRVHSQFLGHPIAGDQIY-------------------------------------------------------------------------------
>UniRef50_B1AIA2(85-288:315) Pseudouridine synthase n=18 Tax=Ureaplasma RepID=B1AIA2_UREP2   E=2e-28 s/c=0.63 id=25% cov=65%
-LDIIYEDKNILVVHKPIGLIVHEDNRYKNDTLQNRikkylvkkdeYHPFDESAFVPSLCHRLDLNTSGLIVAAKTANALRVITEMFKNNDVIRIYKCLTYNQlPKNNDVIYNFMYKADDNTMIVQNFKTKFNKTAITKYTYIDKYK-----------KYFIYDIELLTGRTHQIRAVLNFLHAPIVGEQKY-------------------------------------------------------------------------------
>UniRef50_C2L0N0(2-191:206) Pseudouridylate synthase n=1 Tax=Oribacterium sinus F0268 RepID=C2L0N0_9FIRM  E=4e-28 s/c=0.67 id=29% cov=69%
---IIEETKDYLVFYKEAGLDS-----------------EKDAPKDCLPIHRLDKVASGLLLYGKNKEAAAALSRQLTEKKIKKRYHiVVPKGeegkALPEEGCFQDYLYKDSKKQKCFPVKSLRKGvKEAILRYKILE-----------ENGEWMLLDVELETGRFHQIRAQFASRGFPLYGDGKYGSRQKGTVG----------LHCYQLSFLDVKTGEERGFE----------------------------------------
>UniRef50_B7G895(96-326:383) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G895_PHATR  E=4e-28 s/c=0.55 id=26% cov=77%
-VPVLFQDDQILVVHKPSGVAHHNDADtGRLGILNLIRHQqttgRFAYPHRLYGVHRLDRVTSGILVLAKTPGAAQILTQAWREDRVTKYYVGLSGNKATTsKQGHVRGRMIRGRRRSWLLTRETHGSNVAHTRFFTagLGHLAPPSSTLTNVSPK-TLLLFRPTTGRTHQLRVAAKSVGLPLWGDPVYRDGRHRTENASTP--SRTLLHAA--------------------------------------------------------
>UniRef50_B8LDV9(282-587:590) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LDV9_THAPS  E=7e-28 s/c=0.41 id=26% cov=89%
-IHILYQDDDLLIVSKPPGMVCYHNKKTSAGKITTSRKKKSRAANNGkddgsndggdgklmdisledalidmafplstvnpsarGIVHRLDRGTSGAIVLAKNDETHLRLVASFFLRKATKVYSALVPGSClqNIDGDEDANVSAMLTIGSEGEIDLPVDRRPAKSKYRVVKMYGHQEEQTQQPTPEAILLEVQTLTGRKHQVRVHCASgLGRPIFLDPLYstkpaaaasapkqqsrdkkkaqkGGKETEIVDDEALPTAIQnvlkvgryhpeqfFLHAKSLSIL------GVTVDAPFPTWWSDTFDEWELK-----------------------
>UniRef50_C3XDX0(91-260:279) Pseudouridine synthase n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XDX0_9HELI  E=2e-27 s/c=0.73 id=29% cov=66%
---VIFEDDDILALDKSVGI-------------ESYSLLKTYPHYKL--INRLDKDTSGVILLAKNEKMRQKAIQAFKQKEVEKMYFALIEGKVYEEINIEKKISTQKDSKAKSYV--DNEGLYAQSIVTPLQTFT-----------HTTLVSVQIPTGRTHQIRIHLKSIKHPIIGDIIYNKTSLIK-------AKRLMLHCQKTSL----------------------------------------------------
>UniRef50_Q602D5(81-259:281) Ribosomal large subunit pseudouridine synthase n=3 Tax=Mycoplasma hyopneumoniae RepID=Q602D5_MYCH2  E=5e-27 s/c=0.69 id=28% cov=69%
-LKIIYQDENILLVDKPQNLQVHGGKFNLDLAVWNYLKIPENQVFKPSHIGRLDKKTSGIILYGLNYQSVVELNQ--KQKFFEKIYTFKSDINLKNTIKTDVFIRKNNFQQKMEVTLKSPNSFFASTTFYSKNQKKF----------------AILHTGKKHQIRVSLSHLGFPIFGDEKYGGTRDKI----------LYLHSFSLKF----------------------------------------------------
>UniRef50_B8BW13(24-282:614) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BW13_THAPS  E=3e-24 s/c=0.44 id=27% cov=83%
--------NHIIAL-KPPSVVCHHSGWtgsraklkrgeepeipmlqrvrealHDIGTRDLPDEQKAKV-RKVNLVHRLDRGASGCLLLAYADDdgaevanasvsgSTAMLIDALASPESTKTYVALVRG--EGILREEDFKTKGWFNVTRPIKDESGEEKDATTWFNFVA-GQPETVEDGIERPRMSLVLARPMQGRWHQIRKHLNGISHPILGDTTHGASTVNREWKEKRNLPgeRICLHLARLQL--PPTEavpEGIDVCCPLLDDMLDML-----------------------------
>UniRef50_B7FYH0(89-308:311) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FYH0_PHATR  E=3e-26 s/c=0.55 id=31% cov=78%
---ILARTDRYVVVAKPPTVVCHhsewtGSRSDPFQIPMLQRTREAMGGNCVNLVHRLNWGCSGCLLLTYAADTADAeiyipnttatLIASMKETASLKTYLALVRGEGLLQGRDFKQEGWFKVDRPIKNEKGILN--NATTWFRFVA--GQDNDSGRINQPRASLVLARPETGRWHQIRRHLNGLSHPILGDTSHGNSHVNREWRDLRGMPaqRTCLHLARLQL----------------------------------------------------
>UniRef50_Q14NQ9(91-277:312) Hypothetical rna pseudouridylate synthase c protein n=1 Tax=Spiroplasma citri RepID=Q14NQ9_SPICI  E=3e-26 s/c=0.65 id=28% cov=68%
-LQVVYEDDNILVVDKPHGVEMY-SKFHTSLDAMVQHYLiqkheyhpEDEQSFVISHVHRLDKLTRGLVLYAKNKITLDLLLAKInQKESIEKKYLAKCEGIIKeTDFTLTGYLYKNEDKQKMVFTKtVQPHAKVVKTHFRV-----------QHQLTNATWLEVTLITGRKHQIRASLSYLHHPIVNDIKYGAKQETK------------------------------------------------------------------------
>UniRef50_D0N321(279-458:556) RNA pseudouridylate synthase, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0N321_PHYIN  E=4e-26 s/c=0.67 id=27% cov=59%
-VRVVYEDDDLIVVSKPPSMPTHPCGAYRHNSLHTILQATRPDLPQLNIVHRLDRLTS-------------------ADRQASKTYLARVRGRFPDvlssevqdklvtqaKEICPASIITFPEEGavliscplrclsaRDGVWECHEEGKPSETLVRLVRTDKC-----------TSLVKCKPVTGRTHQIRLHLQLIGFPIANDPCYGG-----------------------------------------------------------------------------
>UniRef50_Q4D881(103-444:474) RNA pseudouridylate synthase, putative n=4 Tax=Trypanosoma RepID=Q4D881_TRYCR  E=5e-26 s/c=0.35 id=26% cov=80%
-IHVVHDDDAVIVCVKNGNLPVAEGGRYSGNTLVGLLERRDavsfvsekysaarqkmdqtreedgdagvsvhKVPASYYPIHRLDKETTGLVVLAKQLAAARALSRQFEKqseritaqvskrtdpagdglstavfekllaeeKVVTKVYVAVLAGAGPEgaDFVMCDRIGLLFDSLWNEGDTEDakkhnklkklkmacfpvnlkenpkRHGRPAASRVRILSSDK---------KLGVSVARVDILTGRTHQIRIHCAQLGYPVLGDKLYetttpgvvggccavpddtyiarakGNEGLVSAAAPRLRVKRHLLHAAVLSFLHPISEERL-------------------------------------------
>UniRef50_Q6KHG9(110-310:314) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Mycoplasma mobile RepID=Q6KHG9_MYCMO  E=8e-26 s/c=0.59 id=27% cov=70%
-LEIIFENLDILIINKPNNLIMHSSKNSLDEQVLNYLNYVKIDSFVPTHIGRLDKETSGLVVYAKNYKTLIELLD--KQSDFEKIYTFIPFCNLSEKDVLVTVNISEDEINKKMQISNE--GKKSITRI--------------FYDGNSQRYYAQILTGRKHQIRLVLAdFLKCPILGERKYANLTKD---------KRLFLHSYKLTF----------------------------------------------------
>UniRef50_B7XJU4(78-324:331) Diaminohydroxyphosphoribosylaminopyrimidine deaminase n=1 Tax=Enterocytozoon bieneusi H348 RepID=B7XJU4_ENTBH  E=1e-25 s/c=0.48 id=28% cov=62%
-IPTIYIDDEITVVNKPFGIPCHPVGAYHYYTVT----KTIFKNKPVGCVNRLDIPVSGVLIIntCNQKRIHEYLLNS------KKIYIAKVIGQFIFSDEQLHKLGIEKRisngksiiivnkslllDPKTKKQKISDDGKFAETHFELVSY-----------QNQYSMIKCYPITGRTHQIRVHLAYIGFPILYDTLYG------------------------------------------------------------------------------
>UniRef50_B5JF54(26-238:244) Pseudouridine synthase n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JF54_9BACT  E=1e-25 s/c=0.55 id=28% cov=77%
----------LLAIEKPAGVLSHPNKKGEKAKALLDAGYDEKRQAYsvldtesgetrlVYLLNRLDSATSGIVLLALEEGTAKAALKAFETKNVRKTYQALVFGAPR--GGPPLWRDRLSVKHAEGGVRASaGGGLSAETKLVKVELLPGVPL--------VSRLTLMPITGRTHQLRIQTSKRRIPIVGDRTYGDFQKNKMAAKK-GMKRLCLHCVGTELQYQLSGRSFRFKA---------------------------------------
>UniRef50_C4XE77(99-275:296) Putative uncharacterized protein n=1 Tax=Mycoplasma fermentans PG18 RepID=C4XE77_MYCFE  E=2e-24 s/c=0.65 id=23% cov=68%
-FKIIYEDDNILIVSKPINLAVHSENNCLDKQVLSYLKYNQKDSFKPSHVGRLDKVTSGLMIYAKNYATLVELNY--KTGFFEKIY--KLKSDFNEVKKLVEINIQHDEKLHKMVVTNNAKDPLAKTLFYTKNNE----------------IFASILTGKKHQIRLSMSHLKTPIYGDIKYDGKK----------ADRLYLHCYSITF----------------------------------------------------
>UniRef50_Q6F0Q2(103-302:323) 23S rRNA pseudouridine synthase n=1 Tax=Mesoplasma florum RepID=Q6F0Q2_MESFL  E=2e-24 s/c=0.57 id=23% cov=66%
-IDVIYEDSNLLIVKKPYNVEVHsPVKTSMDDIVKNYLFDTNQYNPSeensyvISHIHRLDKLTSGLIMYAKNKQTHDIMVEAIQDKeKIEKYYRCRIDVPVTESLIAKGWIKYDPIIQKSVFSEEfRSDYKEATTIFNVVS---------LDVTNEQTELEVQILTGRKHQIRATLEYYGASIINDSRY-------------------------------------------------------------------------------
>UniRef50_D1J7I2(82-267:278) Ribosomal large subunit pseudouridine synthaseC n=1 Tax=Mycoplasma hominis ATCC 23114 RepID=D1J7I2_MYCHP  E=3e-24 s/c=0.61 id=21% cov=68%
-FKVIYEDKNLLIIDKAPNIAMHSEENCLDDQVLKYLNFKKVSSFRPASIGRIDKKTSGLVVYAKNYKTLVEFEN--KQNKFDKIYQFVSDFDEDVLDI-TVRLKKDIKN--EKMIVDNNFGVKAQTIFYKEGNRKF----------------AKIITGKKHQIRATLAYLKTPILGDIKYGGK----------FAKRMYLHSYSIKF----------------------------------------------------
>UniRef50_C1FHP0(253-672:730) rRNA/tRNA pseudouridine synthase n=1 Tax=Micromonas sp. RCC299 RepID=C1FHP0_9CHLO  E=6e-24 s/c=0.27 id=30% cov=90%
-LHVVYEDEWLMAVSKPAGVMTYPAHRLRGESVVSRAVHHLSVSAarrrgrlpyssedlpeesgvgtpvgtpggsfagawtssqvEPIAVHRLDLETSGVLLLAKDKRVASELQAKFEARGVRKTYLAVCAVLEDAEAHKATATRRVDfeadvdtdvdsdadmdadvyadtdgdelgvfdesdldddddddayedpddeldeldepgvvrvvnaaigdpepgtrrsaaaDDGGRCVRAVTPDGKPARTEYQCLSSrlgvptqVTMPDGVTRRTVVGTALVLARPLTGRTHQVRLHLAHAGFPIVGDGLYGvdyasvaasigafrlsgggitreereaaarrrllfassspssssavsprddasaggeSPGSESPDDVPSPCARLALHAWNVDVLHPRALVPLRLCVDMPRDMTDLARALG-------------------------
>UniRef50_B8LCC0(25-308:332) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LCC0_THAPS  E=1e-23 s/c=0.39 id=29% cov=80%
---------------------------------------RRQLSRKPYLVHRLDHRTSGAVIVGFDSKSAGVLHGRLRGGEARKLYVALVRGDLRERFRQaaadgccdgglsaILPERNDVEEASKMKNVEKAQTyvaseyttkitvdlpinvkvdgvdveKDATTDFYFIASMCLDEDDSGRANDDtakvpftnkaVSLILCHPITGRTHQIRRHArKAFSSPVVGDREHGDSRVNRFWREKVGLDRLTLHCWYLDLPQAeedcvedrrgvdavmeeVSKTRIQCMAPLPPDFATALKHEKLKPLWEEVLRME-------------
>UniRef50_Q4A6V6(82-260:281) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Mycoplasma synoviae 53 RepID=Q4A6V6_MYCS5  E=5e-23 s/c=0.61 id=20% cov=69%
-FQIIYEDANILIIDKKENLVIHGEDNSLDNQVLSYLKHKQIDSFKPSHVGRLDKETSGLIVYAKNYLTLKQLNE--KSFNFKKVYQFKSDFLSSSPLELKLYFYKDENNKTKISKTQKENSKLAHSIFYCENNKKF----------------AQIITGRKHQIRLSLAYLNKPI----------YGDKKYKGKKSTRLMLHSYYLKF----------------------------------------------------
>UniRef50_UPI000185C39D(45-303:317) RNA pseudouridine synthase family protein n=1 Tax=Corynebacterium amycolatum SK46 RepID=UPI000185C39D  E=1e-22 s/c=0.42 id=24% cov=80%
--------DEFLVVDKPPFLPATPNGRIVANT-VQERLRRSLGESEIVAVHRLDLLTSGLLLLSRNPATRARYQQLFQNQEITKEYECLTVMPDDWHVgeTRDVTLLLDPNPAGRGVKVVEtdvsaraaaknPKFKLARTTVTFLGPVAADIGDvlassrgggsgggatsasiplhavgcgcgHCGSSMQVGYWRLQPHTGRTHQLRVTMDWLGYPILGEDTYGREAGAQGPSASAGSaptytPQLRLTATALAFVDPVTGER--------------------------------------------
>UniRef50_C5K8M1(333-520:602) Ribosomal large subunit pseudouridine synthase D, putative n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5K8M1_9ALVE  E=1e-22 s/c=0.57 id=26% cov=70%
-------------IDKPYDLRVDGNDFDCTVEKFVRDIPHARPGslkipmDKFRLANQLDFATSGALVLTLNKTADRETSALFQFRLTKKVYIAVCEGWVGDDELMKPRIITTG-------ISSEGGGKMSSTIAVPVST-----GHLLCDDIKCTVYILRLLTGRRHQLRLHLSYIGHPILGDYTY--STHLPKGGRGPTLPRMLLHAWRLTLP---------------------------------------------------
>UniRef50_Q86K31(117-381:386) Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum RepID=Q86K31_DICDI  E=3e-22 s/c=0.40 id=20% cov=83%
---IIFENQYFLVIDKPHGINVGPIVDHLHNnfTSFVKDWLKKRNNNNdnnliLYNPHNLDSPTRGLFVIAKDFNFLSKFNKLLSDKKVSKKYKAFIPIKENEENIEIKPgiykhfmeITNHSPKKLFDEQNQDNSLKECLLKVLKVERKEIYVPLGlkdvsidllqddlqfddigkgdfrkQTKKLLFNVVEIQLITGRTHQIRAQLSKLGFPLLSDIMYGGTSLNHLITDDNDIKNfeskyypkmIGLVSFNLSFQCPITNENFNF-----------------------------------------
>UniRef50_C2MA71(89-303:341) Ribosomal large subunit pseudouridine synthase family protein n=1 Tax=Porphyromonas uenonis 60-3 RepID=C2MA71_9PORP  E=2e-21 s/c=0.49 id=21% cov=78%
LIEELYRDEQFIVLHKRPGIPTISVGGASKSSLfqVVTHHLKKvDPNEKIFLLNRLDRDTEGIIIVARDRQLQQDLLAEWHSFVLFNSFEAVVLGALDTSsgelTTRPTKDKKRGSDKRRTSTSSGRDKKPAsfRASYEVLST-----------GPYITRLSLSLLT-RNNSIRSTLASIGHPLLGDHR------ANDSIAPDLSKYLALRATELAIFHPIKRQKMLFT----------------------------------------
>UniRef50_B8LBQ6(150-348:405) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LBQ6_THAPS  E=5e-21 s/c=0.52 id=34% cov=60%
----------------------------------------------------LDRATSGLLVVAKTKPAMVDLSSQFKHRKVKKTYTAIVNGDIQERPESSISSREAKqlgvcientgsHDFRWQFVDEELDGQSAVTIWRTVDKSSLEYAW----NNTIAMVELKPKTGRYHQLRRHMAWVyGCSIVGDKSYDGSGQAKLLRNE----GLYLCSNKVTLQHPFYNTP--------------------------------------------
>UniRef50_C8PKX0(69-453:470) Pseudouridine synthase n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PKX0_9PROT  E=2e-20 s/c=0.26 id=30% cov=83%
-LKPIFECDAFAAFDKPSGILSHPSGRNSPYN--MYDEIWSLYGQDACVAHRLDLETSGILIVAKDKDAARELKECFEQRRVMKSYLALVQGDLREGLRGDLqsaacngeiescyalgfdeicgskfagdavslpssvsdlrdTLALKGTGNKFGFNILSNGAsrglwcdalsydaqvkfnsgaptgdvdsrsefddlscgvsdklKPAITmssadnghkpcalsaakslpatskgcvnlkKFEPAKYAKFSEklkflkdfegfvidapiapsgefadlkirmkisrdskeaitlirPLRYFSDIDASLIECYPLTGRQHQIRLHLFAAGAPILGEPLYGLSREQAERIldkkmdetervRTTGAPRLLLHANAICFE--LGGERYEIKS---------------------------------------
>UniRef50_B9Q0D6(257-567:713) Putative uncharacterized protein n=1 Tax=Toxoplasma gondii GT1 RepID=B9Q0D6_TOXGO  E=2e-20 s/c=0.32 id=27% cov=85%
----------------------------------LLHQLRFSMDETPKLLHRLGKEVTGVLLLGRTKQTAQVAVDRLRGGTFGVlTFFALLHGRPPggrREGVIRIPLAENEAGVMVPTAVQ-RGGSVSVTRWKLLKvaspqTRDVKGDAEQSHACGFSLVELEIrHQQCRHQARAHCLYgLSCPIVGDRVYGPltsrwrqlastgaasftsedrvsatagtarlsvrndagdasahaatdeETRNRVAAKSEEKRRlaearatlgvtapsmLHLHSRAISFE-TFAGRPVRIQAPLPPHMRQAASRLGWEFFVEQLDAnlSPLTADMGIDEE---
>UniRef50_B7G4K5(55-405:418) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G4K5_PHATR  E=5e-19 s/c=0.28 id=29% cov=82%
---VVYETDHFLALNKPPDLRMdghHPStvlklltywypppafqnlqSKGLLEKVSEFENYRNIEGNELRPCHQLDYATSGILLVARNRQAADQARVSFEERSTRKTYLALVHGHLSvpsnipvmRRTDIDERMGRLEEiyrqSRRKHRKDTYRGYQPAHglfqqlqqqhnhilnlswkevkasgktepfdraaevfnklqyktlfpedksaelslptffrdesedpntlfiyasvaqvphdfamrinpsmsnasaylkvgdssLDYKPSLTRCVILKHAAIRGQPVTKVRLEPRTGRRHQLRVHSALLGHAIVGDQTY------KAPGSPDLTDRMCLHSQCLEI--PLFEELIKVEAPDP------------------------------------
>UniRef50_Q06244(7-205:254) Pseudouridylate synthase PUS5 n=6 Tax=Saccharomyces cerevisiae RepID=PUS5_YEAST  E=9e-19 s/c=0.48 id=22% cov=62%
-IPIIFENTHYFIVNKPPGIPSQPpdcrtwgrTHPNLDPTPLLerfkAIYYSHREVELCRTVHRLDHCVTGGMLIAKTKDGSVKFSRFLQKggnngYKLQRKYVAI----VESSGRFNKPNNYEIKYGPKYNFLISHGGRE-ITKFKEVDENC---------------IVLQLVTGKKHQIRNHVSQIlNQPILNDKRHG------------------------------------------------------------------------------
>UniRef50_B7G1Q0(180-423:607) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G1Q0_PHATR  E=9e-19 s/c=0.39 id=23% cov=80%
---IVAEDTDkgWLVIRKPSMVPVHMTVDNcRENVADCLKQARAWQSPtadardvYITTPQRLDQNTSGLVVVATHKPFAAYFASLLRSKTarqlsgdgddrnheslgsVHKLYRCLPSIRAPKRFVEHPPDDTQWPECLLKIVKVGNvcelVGSPAgQDLAEALWQDASGQAKRIPPQAKAVVeVEIELLTGRTHQIRGQLSTLGFPLVGDAQYGGAVPRNPTNEQFyiGTEQLALQCCELAFRDP-------------------------------------------------
>UniRef50_A4BBP0(66-269:270) Pseudouridylate synthase, 23S RNA-specific n=1 Tax=Reinekea blandensis MED297 RepID=A4BBP0_9GAMM  E=1e-18 s/c=0.47 id=27% cov=71%
-IEIFY-DEELLslkplkaellhdagqysVWNKPNGMPLSGTDWGDFNSFERAVELATHGERECYWLTPFDYQAAGVQVLAHSRKAASQLTEQFDPeglKGATLKYRCDVEGDFNDEGECT-------------------------TDLEDGAVSTRFSKVRFDARPNRSVLEAELITGRDDQIRRQLSALRYPVVGDEDYG------QNAEEQGLLR--LKCVEVRFTCPMTHETLVF-----------------------------------------
>UniRef50_C4R5D7(1-229:249) Putative uncharacterized protein n=1 Tax=Pichia pastoris GS115 RepID=C4R5D7_PICPG  E=2e-18 s/c=0.42 id=20% cov=68%
MIRPFFEGPGFLVINKPPGIYTQPPSfrqGNRDKSNELLPLLEKQLQTTLRQVQRLDYETTGGLVVSTNKYTARMFHRNMQalsnnildgrhrssnkGYILTKRYIALLN-KPVTSIYEQLPKTSDGWRLLETQDIDESNSSS------KLLLSKVRTIESCRPMHDKFPLMFELITGRKHQIRRQIKQVfGTTIVNDVKYG------------------------------------------------------------------------------
>UniRef50_P70863(126-217:221) Pseudouridine synthase (Fragment) n=1 Tax=Bartonella bacilliformis RepID=P70863_BARBA  E=4e-18 s/c=1.02 id=33% cov=35%
ML--LYEDPKIFVFNKPAGLAVQGGSGLTRHVDGMLEAWRNKKGEKPRLVHRLDRETSGLLVVARSXXAAQALTAAFRTREMKKIYWALVR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4RUK5(129-341:371) Predicted protein n=2 Tax=Ostreococcus RepID=A4RUK5_OSTLU   E=7e-18 s/c=0.44 id=21% cov=62%
--------------HKPAGVSVVPTVDNVKESCLAMLERAAGLKEGtLKPIHRLDVGTEGVLVLGTTSAFAKEFGDMLADRSVTKVYRVLTENAVPRGVHIHDAEPATEGPRKMIMTKVDTDdidgeiersaergggerggvSGPKRCILRVLKSENIAPARWET--------KVELLTGRTHQIRAQFAALSAPLVGETLY-------------------------------------------------------------------------------
>UniRef50_C7LVN5(79-263:281) Pseudouridine synthase n=1 Tax=Desulfomicrobium baculatum DSM 4028 RepID=C7LVN5_DESBD  E=1e-17 s/c=0.50 id=26% cov=61%
------RNESFAALAKPDGLHTVAG----QEAACLESCLPGLGLEGWELLNRLDCLTSGLVLAAAEKRDAAAYKVWQDAGQVSKWYLALARGEVA---TLECRGRILDDKRSVVRVTADEDEPLRWTRVRALRQID-----------GNTLLLVKIFKGRRHQIRAHLAHAGHPLIGDPVYG------------------------------------------------------------------------------
>UniRef50_C8NNL7(147-291:329) Pseudouridine synthase n=8 Tax=Corynebacterium RepID=C8NNL7_COREF   E=4e-17 s/c=0.63 id=28% cov=55%
------EDLEYFVLNKPRGM--HSTMSDDLGRPCVGDLVSEKtaSGQRLFHVGRLDADTEGLLLLTNDGELANRLMH--PKYEVRKTYLATVRGEAGPNLVTTL-----------RKGIELEDGPAKADYVQIIDTFQ-----------GKSLIRLEIHEGRKHIVRRMLDEAGFPV-------------------------------------------------------------------------------------
>UniRef50_D2V9L8(190-561:579) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2V9L8_NAEGR   E=4e-17 s/c=0.24 id=25% cov=89%
-IHVLYEDKDVIVVNKPVGYAVHSSKSKP-ESETMIYAIRNYvlskekekekskkkskqttntLPLNINLAHRMESQMSGVLICGKNSHSIQKLSEQFlPNTNLQKQYITVCavpninslkkklnpfyhlkeefdedeettddeegsnlsekdilssfgvskkpdrfadlnlgeaeelfvddYGDMEEDGDEELDLLEgmgeehetlDLSGGWKDMRKEHEMLKEkyekatknttltlegdlkfvmhpeynvqvlqrAGTHElpstKVLRNIKTVVNVlELNEDNRIALATVSIPSGSVQQVRSHLATNGIPMLGDFPYFDQVDNRIPiglSKNLNVNKIFFHLYKIVFQHPTSGKNVIVKAPLMSPMKEFVEK---------------------------
>UniRef50_C5DSY2(5-202:250) ZYRO0C03894p n=2 Tax=Saccharomycetaceae RepID=C5DSY2_ZYGRO   E=5e-17 s/c=0.46 id=27% cov=66%
VLKIVHECNNYFLINKPPNVLSQPGNVHRWiyhglyknqhvNTPkVLLDELKSQSStskrdfDSWRLVHRLDSCVSGGLLVATNKNAAKYFSRNLKEggnkgYKIDRRYVA----------MIDNPGKGDPKYLNEYGIIDKMG---MVSKYRRFDEKC---------------ILVELSTGQKHQIRKHLSHIlKQPVLNDVKYGG-----PLLPHTDPLQIALHAA--------------------------------------------------------
>UniRef50_C3YVI6(172-418:418) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3YVI6_BRAFL  E=7e-17 s/c=0.36 id=21% cov=82%
---IVYDDGHIVAINKLAGLPVQGqTPEQLSINSLLPELGAALEASDLSIVKPLDWHLSGIVLLARTPEARAEVFNvtkaARQRDKFYRKYWGVVIGNLDPSEDCTSV-------KPNPSCSEKEGG-----------SELSDEIQGPQSGAGICPV-------FVDQLQVHLTTKLCSILGDHVYssrvgsvaGMPALMEPTNVGPRTQRvpkdilkkmnlraiqmhkvpVHLHCGEMLLPG-YRGRDVRITAPLPKHFLWTLQLLGLEDPTNE------------------
>UniRef50_B6W881(84-187:195) Pseudouridine synthase n=2 Tax=Bacteria RepID=B6W881_9FIRM   E=2e-16 s/c=0.85 id=28% cov=35%
-LDIIYEDENIIIIDKKSGVLSHAASSSDYGKNLVdqmtSYLYKtnkvnsRDLTFRPSIVNRLDRNTAGLIIGAKNAKSLRALNEAIRQGKIYKYYLTLVEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6AKZ6(34-259:544) Putative uncharacterized protein n=1 Tax=Desulfotalea psychrophila RepID=Q6AKZ6_DESPS  E=3e-16 s/c=0.39 id=20% cov=81%
--PIIYKDAQLLVVDKPTGFSSQAmTEGEVGITEWLALHLQYQIDLYSS----LTKSCSGVLLLRRKNQIEKAENDQ-PVKIAEKKYHFISA---------KRYRGQTEEDGSWLVERDNSITEESV-RFRFLE-----------EGRDYSLYEAATLSCCRR-VQEFAEESGIAIVGD------------GADSPFARLFLHCHSIRLA--ESG--HEFISSTPDSFSFVLKqrdkvlidtaiawerRLGWLQLITNSYRLIQRGELDLP-----
>UniRef50_D0CH73(4-109:120) Pseudouridine synthase n=1 Tax=Synechococcus sp. WH 8109 RepID=D0CH73_9SYNE  E=4e-16 s/c=0.82 id=36% cov=38%
----LLRDPWLMAVDKPAGLLSQPGLGQEQGDSVITRLQQQ--DPSLRLVHRLDRDTSGVLLLARSADALRRLSALFTERRINKLYQADVEGELHGRGCIVSP-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8WXC0(63-204:273) Pseudouridine synthase n=3 Tax=Firmicutes RepID=C8WXC0_ALIAD   E=5e-16 s/c=0.61 id=28% cov=55%
----------VLVLNKPVAYLS--TVSDPLGRRTVMQLL-PPIRERVYPVGRLDYDTSGLLLFTNDGELTQRLLH--PSREIEKVYRVSVRG-----------IVDRETRRALMEGVELEDGVTAPAKVEVLRQADR--------EDGVAVVHLAIHEGRNRQVRRMFERLGLPVL------------------------------------------------------------------------------------
>UniRef50_A4J3M3(65-203:309) Pseudouridine synthase n=167 Tax=Bacteria RepID=A4J3M3_DESRM   E=7e-16 s/c=0.62 id=25% cov=53%
-----------LLMNKPRGYVT--TLSDERDRKTVVDLLK-GVEQRVYPVGRLDYDSEGLLLLTNDGELTQALTH--PKHKVKKTYLAKVDGIPETEEL-----------KAMAKGLVLEDGPTAPADVRLAGT-----------GDNRALLEISIHEGRNRQVRRMCEHIGYKVL------------------------------------------------------------------------------------
>UniRef50_Q47QM5(197-337:375) Pseudouridine synthase n=3 Tax=Actinomycetales RepID=Q47QM5_THEFY   E=9e-16 s/c=0.61 id=26% cov=53%
------------ALNKPRGVVS--TMFDPEGRPTIGDYAAQigPIEERLFHVGRLDTDTEGLILLTNDGELANRLTH--PRYKVTKTYLAKVPGPVPRDVI-----------RQIRKGVELDDGFVKVDSFRVIDNIEPK-----------ALVEIRLHEGRKHIVRRLMKAVGHPV-------------------------------------------------------------------------------------
>UniRef50_C6PYN7(103-173:173) RNA-binding S4 domain protein (Fragment) n=1 Tax=Clostridium carboxidivorans P7 RepID=C6PYN7_9CLOT  E=1e-15 s/c=1.21 id=25% cov=27%
-IDVVYEDSDLIVVNKQPGMVVHPTKSYPNGTLANGLLYYFKEKGEqciVRLVSRLDMDTSGLIIIAKNQFA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q7VBH8(65-204:237) Pseudouridine synthase n=1 Tax=Prochlorococcus marinus RepID=Q7VBH8_PROMA  E=5e-15 s/c=0.60 id=23% cov=54%
----------VILLNKPTGVIS--TCRDTHGRKTVLDLLPDNLQKGMHPVGRLDKDSRGALIISNNGLLTLHLTHPRFNHK--KRYSVLITGVPSKNTLKKWRNGIEIDKKTTRKALV----------------------NIVKRQGNNTLLEIVLFEGRNRQIRKVADKLGHPVI------------------------------------------------------------------------------------
>UniRef50_Q5ZXB8(26-174:222) Pseudouridine synthase n=2 Tax=Legionella pneumophila RepID=Q5ZXB8_LEGPH  E=2e-14 s/c=0.55 id=20% cov=57%
----------LILFNKPYGILTQFTGELPEQTLSAFIKL-----PGFYAAGRLDKQSEGLLILTDDGKLQHRLTH--PKFEKKKHYWVQVEGVPTD---------KDLQPLRKGLVIKDITFLPA--EARLISEPKIWPRIPPIRERKHiptTWLEIILREGKNHQIRKMTAAIGFP--------------------------------------------------------------------------------------
>UniRef50_B2V6W2(54-204:244) Pseudouridine synthase n=5 Tax=Bacteria RepID=B2V6W2_SULSY   E=2e-14 s/c=0.54 id=33% cov=33%
--EILYKENHYFMLNKPAGYIT---ATEDEEYPTVLDLFSDlPIASKLFPVGRLDIDTEGLLILTTDGQFGHRLSH--PKWNIEKEYYAIVEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8QZD4(66-203:240) Pseudouridine synthase n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8QZD4_9DELT  E=2e-14 s/c=0.59 id=27% cov=53%
-----------VLLNKPAGYVT--TMADPQGRPIVTSLI-NEPGLRLFPVGRLDLDTEGALLLTNDGELAQNILH--PSRQINRTYHATVKGRPNREALQQLRRGIMLEGRRTWPARIRE----------------------LRRNQESTTLEVIIHEGRKRQVRKMFAAINHPVL------------------------------------------------------------------------------------
>UniRef50_Q042N1(65-215:245) Pseudouridine synthase n=3 Tax=Lactobacillus gasseri RepID=Q042N1_LACGA  E=4e-14 s/c=0.54 id=26% cov=35%
---IAYQQYHYFLLNKPKGVIS--ATEDRSQQTVISLLKTKDRYQGIAPVGRLDKDTTGLLLLTNDGALAHELLA--PNKHVAKVYRAKIAGVPDPE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_O05668(78-218:256) Uncharacterized RNA pseudouridine synthase ML1370 n=49 Tax=Actinomycetales RepID=Y1370_MYCLE  E=4e-14 s/c=0.58 id=25% cov=53%
-----------LALNKPRGMYS--TMSDDRGRPCVGDLieRRVRGNKKLFHVGRLDADTEGLILLTNDGELAHRLMH--PSHEVSKTYLATVKGAVP-----------RGLGKKLSVGLELDDGPAHVDDFAVVDAI-----------PGKTLVRLTLHEGRKRIVRRLLTAAGFPV-------------------------------------------------------------------------------------
>UniRef50_C0W3E8(133-287:325) Pseudouridine synthase n=1 Tax=Actinomyces urogenitalis DSM 15434 RepID=C0W3E8_9ACTO  E=6e-14 s/c=0.52 id=25% cov=55%
-------DPDVItvLLHKPAGVVT--TMEDPQGRPTVADLaeqfisehrteLEHPESVRLVHVGRLDTETEGLLLLSNDGDLAHRLMH--PSFEISKTYVAIVEGQVEGWVPRKLRRGIELDDG--------------------LAQADRVVVKDAGPSG--SIVEITLHSGKNRIVRRMLDAVGHPV-------------------------------------------------------------------------------------
>UniRef50_C1F236(86-230:406) Pseudouridine synthase n=8 Tax=Bacteria RepID=C1F236_ACIC5   E=1e-13 s/c=0.55 id=24% cov=55%
-------------LNKPKGYVTTVSDPEGRHTVMEFFHGRGKGGERLYPVGRLDYASEGLLLMTNDGALANTLTKA--SSHVEKVYLVKVSGRPTEEQLEQIRAGIMIDRGRPGEGRV----MTAPAGVRMVRDAENP------------WFELTLIEGRNREIRKMFEETGH---------------------------------------------------------------------------------------
>UniRef50_Q04F57(49-204:237) Pseudouridine synthase n=2 Tax=Oenococcus oeni RepID=Q04F57_OENOB   E=1e-13 s/c=0.51 id=28% cov=57%
--DIVYVDNkkineesfEYYLLNKPAGYVS--SNRSYPNQPSVIELIKTK--TRIFSVGRLDQDTTGVLLLTNDGELTQKLTH--PKHRIKRTYAAWVKGIVNEDEIEQL-------TKPIRFDGEIYFPQAA----RILKVDQKRQE---------SLIEITIAEGKNHEIKKILDFIGHPVI------------------------------------------------------------------------------------
>UniRef50_A0Z1Z6(25-208:208) Pseudouridylate synthase n=2 Tax=Proteobacteria RepID=A0Z1Z6_9GAMM   E=5e-13 s/c=0.42 id=21% cov=59%
---------DIILLNKPFRVLSQFSDRDNDpPRLTLANLL---SAPEFRVAGRLDYDSEGLTLLTDDGKLQQQIAN--PKFKVWKTYWVQVEGAPKQQAIEQLTSGVVLNDGLTKPAKVRAIDPP--------DLWERSPSVRFRAHIPDAWLEISIQEGRNRQIRRMTAAVNLP--------------------------------------------------------------------------------------
>UniRef50_C0EB54(59-203:248) Pseudouridine synthase n=1 Tax=Clostridium methylpentosum DSM 5476 RepID=C0EB54_9CLOT  E=6e-13 s/c=0.53 id=27% cov=54%
-----YQEHLYLMLNKPQGVVS---ATDDKVHRTVLDLVPPELRRRgLFPAGRLDRDTVGFVLITDDGEFAHNILS--PRHHVPKTYEA----------GLDGPIGENELSVLAQGVVLGDGTKCRPAELTVLQSGERP------------LIQIVIVEGRYHQIKRMFAAVG----------------------------------------------------------------------------------------
>UniRef50_Q3B289(76-209:250) Pseudouridine synthase n=2 Tax=Chlorobium/Pelodictyon group RepID=Q3B289_PELLD  E=2e-12 s/c=0.56 id=26% cov=28%
-----------ILFNKPRNVIT--TSSDERNREMVLDFI--DVNERVYPVGRLDRKTTGVLLLTNDGMLANKLMH--PSSNVKKEYIAV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5KIU2(27-142:142) Ribosomal large subunit pseudouridine synthase A, putative (Fragment) n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5KIU2_9ALVE  E=2e-12 s/c=0.65 id=27% cov=45%
----------------------------------------------------LDIFTSGIIMVAHTYAAYYQLRHQFKKRAILKKYICLVHGHMDEDSGIIDTNIQTYSSSSNSRSKHIPI-----------SSSSSSYSTIINNNKKVSLLEVEIPTGRTHQIRLHMYHIGHPIVSD----------------------------------------------------------------------------------
>UniRef50_Q11WC7(30-186:224) Pseudouridine synthase n=2 Tax=Sphingobacteriales RepID=Q11WC7_CYTH3  E=3e-12 s/c=0.48 id=17% cov=56%
------------IINKPFNMVSQFISSDAVNLLGNLD---FTFPEGTHAVGRLDNESEGLLILTTNKKVTRLLFQGTKKH--TRTYLVLVKNKVSEETLKQLQTGISIRVKGGGNYISSPCEASIVTDAKAIYSYAADTRENY----PHTWLLLTLTEGKFHQVR-----------------------------------------------------------------------------------------------
>UniRef50_Q4XUF6(378-454:1071) Putative uncharacterized protein (Fragment) n=1 Tax=Plasmodium chabaudi RepID=Q4XUF6_PLACH  E=4e-12 s/c=0.96 id=34% cov=25%
-------------------------------------------------------------------------------------------------------------------------------------------------TKEFTLCNVKIHTGRTHQIRVHMRHIGHPLVSDKKY--LDASLSNLDKFWCFRMFLHSIILEFNNP-------------------------------------------------
>UniRef50_C3JBA6(284-428:459) Pseudouridine synthase n=2 Tax=Bacteria RepID=C3JBA6_9PORP   E=9e-12 s/c=0.50 id=26% cov=23%
-----------VLLNKPRNCVT--TSSDPEKRLTAIDLVRNACNERIYPVGRLDRNTTGLLLLTNDGDLAAKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4XSY8(73-214:322) Pseudouridine synthase n=11 Tax=Desulfovibrionales RepID=C4XSY8_DESMR  E=1e-11 s/c=0.51 id=24% cov=53%
-----------LALHKKPGVVT--TASDPEGRPTVFDGLPEvWRGKRLFPVGRLDFFSEGLLLLTTDGELALRLTH--PRWHVPKRYRVTVRGQVTPDML----------GTMARGMRLAEGERLAPVAARVVE----------GPAQDRSILEMELHQGVNRQIRRMCRDLG----------------------------------------------------------------------------------------
>UniRef50_Q2JQ37(33-179:226) Pseudouridine synthase n=10 Tax=Bacteria RepID=Q2JQ37_SYNJB   E=2e-11 s/c=0.49 id=21% cov=55%
---------------KPYGVLTQFTDREGRPTL-----QSFIPVPRVYPVGRLDRDSEGLLLLTDDGRLNARLIDPKFGH--ERIYWVQVEGIPTPQALQQLQQGLIIQGRKTRPAQV-----------KVLAEeptlPPRDPPIRFRRSIPTTWLELTLREGRNRQVRRMTAAVGIP--------------------------------------------------------------------------------------
>UniRef50_C5KUW6(22-171:182) Ribosomal large subunit pseudouridine synthase B, putative n=1 Tax=Perkinsus marinus ATCC 50983 RepID=C5KUW6_9ALVE  E=2e-11 s/c=0.48 id=24% cov=56%
----------LFAFFKPRGMETTCTAGSG--------LRKFLDRGRLHPVGRLDRDTTGLLLLSSDGDCTNRILHS----TINKTYAALVRGVLP------EGLMKKVVSEG----VDLPDGHVDVTRLETINDGDTVPfglvayPLSSIPTNGCSMVRITTTCGRNRVVRRTLCALGHPVL------------------------------------------------------------------------------------
>UniRef50_B2A4P2(59-194:238) Pseudouridine synthase n=2 Tax=Clostridia RepID=B2A4P2_NATTJ   E=3e-11 s/c=0.53 id=26% cov=53%
------ESNVYIMLNKPKDYIT--SKDDPQGRKTVMDLIQ--VKERVYPVGRLDYDSRGLVLLTNDGELANRLMH--PKYNIPKTY---------MVKVDKLPLQDKLDNLVNGIYLEEGLCK--ADHVEILDTKNN-------------ILKIILSEGRKRQIRRMLASLG----------------------------------------------------------------------------------------
>UniRef50_C7H5G4(65-223:294) Pseudouridine synthase n=8 Tax=Clostridiales RepID=C7H5G4_9FIRM   E=3e-11 s/c=0.45 id=32% cov=23%
--DVLHVDDeriyiqknqqlYYLALYKPRGYVT--TASDELGRKTVMELVSD-IPARLYPVGRLDKDSEGLLLM-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1MQ05(64-232:270) Pseudouridine synthase n=1 Tax=Lawsonia intracellularis PHE/MN1-00 RepID=Q1MQ05_LAWIP  E=4e-11 s/c=0.42 id=22% cov=58%
----IHPDKDIIALHgrrvdiqlknkkyyylsmyKP--IKVISSVKDPQNRLTVLDFIPFPWKNyRLYPVGRLDFFSEGLLLITNDGELTQRLTH--PRYHISKVYHVLI----------RERILNTTLKNISKGITLSDGTKLPPAKVRVLSSIT---------ETNTTWLEITLQQGINRQIRRMCKELGLTIL------------------------------------------------------------------------------------
>UniRef50_B3L0G1(123-291:328) Pseudouridine synthetase, putative n=1 Tax=Plasmodium knowlesi strain H RepID=B3L0G1_PLAKH  E=9e-11 s/c=0.41 id=20% cov=60%
------------VLHKPKGFLC--TSNDEKDRASIYSLFPQDimDNYRLVSVGRLDRNTSGVLLLTNEYAWVNKLTH--PKYQRIRTYRVHIEGPAQMKVLKQLatgiYLQDDNRGKENKKIVKKKRTQPA-----FIEILREETIKVKDQVKKVSVLNISVREGRNRQIRKMFEQINQPVI------------------------------------------------------------------------------------
>UniRef50_B0N6F1(58-201:241) Pseudouridine synthase n=3 Tax=Bacteria RepID=B0N6F1_9FIRM   E=2e-10 s/c=0.48 id=14% cov=53%
------------VFYKPKGCVC--TLDDEFDRPIITD-YFTEVKERIYPVGRLDFDTTGLIIMSNDGEFANMIMH--PRSHLEKIYEVSIKGLITGPTLNKLEKG-----------VYLEGVKTLPCKIKVVDKDT---------EHKTTMLKIKLVEGKNRQVKKMFESVGHPV-------------------------------------------------------------------------------------
>UniRef50_Q7UUP0(86-222:395) Pseudouridine synthase n=1 Tax=Rhodopirellula baltica RepID=Q7UUP0_RHOBA  E=3e-10 s/c=0.50 id=26% cov=52%
------------VVNKPVGIVT--TNRDPRGRPRVIDLVPPT--ERVFPVGRLDISSEGLILLTNDGDLAQKLAH--PKFGIQKVYRVVVAGEV----------------RGETMKKMREGIYIAEGLVQV------DGAKIIKARTKATEMEIRLKEGKNREIRRILARFGH---------------------------------------------------------------------------------------
>UniRef50_A4SY81(260-398:587) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=A4SY81_POLSQ   E=5e-10 s/c=0.48 id=29% cov=22%
--------------HKPAGEIV--SQSDPEGRPTVFDRLPKPRQGRWIAVGRLDFNTEGLLLFTTSGELANRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1PIW4(64-233:237) Pseudouridine synthase n=1 Tax=Subdoligranulum variabile DSM 15176 RepID=D1PIW4_9FIRM  E=3e-09 s/c=0.38 id=21% cov=50%
-----------IMLNKPEGVVS--ASRDKRDTTVVDLVAADFPRRALFPAGRLDKTSTGFVLLTDDGALAHDLLS--PAHHVDKQYLVTLDTPLT-----------DAMRAGFAAGVTLADG------------ETMAPAEAEPAGEDPCVVKVTLHQGVYHQIKR----------------------------------------------------------------------------------------------
>UniRef50_B8ET33(75-214:255) Pseudouridine synthase n=29 Tax=Proteobacteria RepID=B8ET33_METSB   E=3e-09 s/c=0.46 id=26% cov=54%
----------VIALNKPRGVTCSRKEAGPLVFDLLPPRFR-LREPALSTVGRLDKDTSGLLLITDDGALLHRLIS--PKHNIAKRYCAKLARPLRGDEAEIFASGE--------MMLDDEAKPLLPAVLRVLSPTEA---------------EVSVTEGRYHQIRRMFAATGNHVL------------------------------------------------------------------------------------
>UniRef50_P45104(142-277:357) Ribosomal large subunit pseudouridine synthase B n=177 Tax=Gammaproteobacteria RepID=RLUB_HAEIN  E=3e-09 s/c=0.47 id=26% cov=26%
---------------KPEGELC--TRSDPEGRATVFDRLPRLTGSRWIAVGRLDINTSGLLLFTTDGELANRLMH--PSREVEREY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1DTU8(64-204:247) Pseudouridine synthase n=5 Tax=Bacteria RepID=C1DTU8_SULAA   E=5e-09 s/c=0.46 id=25% cov=53%
-----------LAIYKPVGYLS-AVGKDRFGRKTLTDFLNElKIPYKLFPVGRLDYNSEGLLILTNDGEFANKVAH--PRNEIKKVYKVKVAGEVSQ---------ETLKKMEEGTILEDGFFKP--DKIKMLKREEDG-----------TWLLVEIHSGKKRIIRRFMDSFGH---------------------------------------------------------------------------------------
>UniRef50_D0SE82(57-195:244) Pseudouridine synthase n=1 Tax=Acinetobacter johnsonii SH046 RepID=D0SE82_ACIJO  E=1e-08 s/c=0.45 id=22% cov=26%
-----YREKVYIALNKPQGYECSHQATHHFSVFDLFDDV--LLNRGIQCVGRLDQDTTGLLLLTDDGQFLQAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5KSQ1(272-359:372) Sulfopyruvate decarboxylase subunit alpha, putative n=4 Tax=Perkinsus marinus ATCC 50983 RepID=C5KSQ1_9ALVE  E=2e-08 s/c=0.70 id=34% cov=28%
----------------------------------------------LYPLHRLDRVTSGIVVFAKTADAARKFEANQRSWPVTKTYIARVTGR------------------------------------------------CSVSEANESIVECIPITGRKHQIRV----------------------------------------------------------------------------------------------
>UniRef50_B2HUK5(60-196:307) Pseudouridine synthase n=9 Tax=Gammaproteobacteria RepID=B2HUK5_ACIBC  E=3e-08 s/c=0.45 id=23% cov=30%
------EDEirrRVLIYYKPEGEIC--SRNDPEKRPTVFDHLPQIANDRWVMVGRLDINSTGLLLFTNDGELANRLMH--PSNEIEREY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0U645(66-200:237) Pseudouridine synthase n=1 Tax=uncultured actinobacterium RepID=D0U645_9ACTN  E=8e-08 s/c=0.44 id=21% cov=50%
-----------LALHKPKGVLS--TMFDPEGRPSLDDFI-DLRKERLFHVGRLDKDSEGLILLTNDGDLTFRATH--PSFGLEKTYIIEFDGILPTGVDKVLLKGVELEDGMGR-----------VLTFKQLSPK---------------WIEVSIHEGRYHIIRRLMEAVG----------------------------------------------------------------------------------------
>UniRef50_B8CBS5(72-209:253) Pseudouridylate synthase (Fragment) n=1 Tax=Thalassiosira pseudonana RepID=B8CBS5_THAPS  E=9e-08 s/c=0.43 id=20% cov=53%
---------------KPLGVTCTTDRRIYDNLIDALQQDGCRPKSRIFPVGRLDKETSGIILMTSDGRLPNAALRGKYKH--PKTYVVKA----------NRPVANDDIKRLREGVPLTAPTLPCKVKAVQLSTLDLSSR----------YLEITLVEGRNRQIRKMLEAIGY---------------------------------------------------------------------------------------
>UniRef50_D2VWU1(68-214:244) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VWU1_NAEGR   E=2e-07 s/c=0.40 id=18% cov=28%
-----------IALNKPESYLC-STQRESSNHKIIYDLLPPEFlnrNPTLGNVGRLDLDSCGLLIMTQDGDLHHRILSA----DVEKTYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C9LMR9(64-203:239) Pseudouridine synthase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LMR9_9FIRM  E=3e-07 s/c=0.41 id=31% cov=25%
---------------------------DPAGRRTVMDYFR-RVRERVFPVGRLDYHSEGLLLVTNDGQLDFILTH--PCHEVQKEYEVVVRGKF----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6IXC3(96-229:551) Pseudouridine synthase n=2 Tax=Alphaproteobacteria RepID=B6IXC3_RHOCS  E=5e-07 s/c=0.43 id=22% cov=52%
--------------HKPDGLVT--TARDEKGRPTVFDNLPPEL-PRVVSVGRLDLTSEGLLLLTNDGALARHLE--LPVTGWLRRYRVRVHGAPDEAQIAKLAQGIIIEGI----------------EYGPIETVVDRSVGAN------TWLTVSLREGRNREVRRVMEHLGLPV-------------------------------------------------------------------------------------
>UniRef50_A6LUE3(60-159:281) Pseudouridine synthase n=3 Tax=Clostridium RepID=A6LUE3_CLOB8   E=5e-07 s/c=0.57 id=25% cov=22%
-----------IVLNKPVGITCTAENKVSDNIISYM-----KYPHYIFPVGRLDKDSQGLILMTNDGEVANR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8BQ39(161-334:370) Predicted protein n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8BQ39_THAPS  E=9e-07 s/c=0.32 id=21% cov=49%
-----------------------------------------------HPVGRLDYDTTGLILFSSDGKLTQRLLH--PRRGVEKEYVATVQGEVNASELREMLANGVETTDGTFaanlIAVTSSNGPSEVSEEdlnNVPEEDEGGDETTDEPyNGPYSDVRLVVSEGKYRMVRRILANSGHPVV------------------------------------------------------------------------------------
>UniRef50_Q1GFA6(123-260:422) Pseudouridine synthase n=3 Tax=Rhodobacteraceae RepID=Q1GFA6_SILST   E=1e-06 s/c=0.41 id=16% cov=52%
---------------KPNGLVT--TTSDEKGRKTIFDALPEDL-PRVMTVGRLDLNSEGLLLLTNDGGVKRQLE--LPSTGWLRRYRVRINGRPQDHEFDVLRKGVVIDG----------------------ERFQPMTISLDRQQGANAWLTIGLREGKNREIRRAMEEVGYPV-------------------------------------------------------------------------------------
>UniRef50_D2VUY3(3-86:133) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VUY3_NAEGR   E=1e-06 s/c=0.66 id=34% cov=30%
----------------------------------------------LFPLHRIDRLTSGVLILGKSSEVARDFSASLKSKQVGKQYIAVAEGICPTEGLFkvDYPLMEIDPLLGIWRAVHSEESKE----------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2W4E4(74-212:247) Pseudouridine synthase n=20 Tax=cellular organisms RepID=Q2W4E4_MAGSA  E=7e-06 s/c=0.38 id=19% cov=53%
----------VLMLHKPEGYTCSTSDPGRI-VYELLPERFMHRNPIVAPVGRLDRDSTGLLLLTDDGPLAHRITS--PKRHVPKTYEVTLARPLSGEEGAVFASGTLM-----------------------LRSESTPLAPAELVVSGPQTARITITEGRYHQVKRMFAAVG----------------------------------------------------------------------------------------
>UniRef50_D0J8G4(456-614:642) Pseudouridine synthase, Rsu n=96 Tax=Bacteria RepID=D0J8G4_COMTE   E=1e-05 s/c=0.33 id=20% cov=29%
-----------ILLNKPMGYVSGQAEDGHEPAVVLItnenrwnedrskTRFNFSQLKGLAPCGRLDIDSVGLLVLTQDGRVARQIIG--EDSEVDKEYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8SIK9(49-196:235) Pseudouridine synthase n=1 Tax=Parvimonas micra ATCC 33270 RepID=A8SIK9_9FIRM  E=2e-05 s/c=0.35 id=27% cov=23%
--EILFDDEiviykefTYLMLNKPKDFIS---ATFDTKLPTVLDLLEFpYSNMELFPVGRLDIDTTGFLIL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q688C2(47-142:235) Pseudouridine synthase n=1 Tax=Mycoplasma mobile RepID=Q688C2_MYCMO   E=3e-05 s/c=0.54 id=22% cov=27%
--DVILVDEKVIskeekvyyLLNKPKNVVT--TLKDNFNRSIITDFI-DEKKYKIFPVGRLDYDTTGIIILTNDGETANKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P50513(82-311:317) Ribosomal large subunit pseudouridine synthase D n=8 Tax=Sphingomonadales RepID=RLUD_ZYMMO  E=3e-62 s/c=1.04 id=31% cov=85%
-LEIVFEDEHLLVVNKPAGMVVHPAAGNYDNTLVNALLYHCagklsgiGGVARPGIVHRIDKDTSGLLVVAKTDPAHAGLAAQFADHSINRRYRAIVDGHPSLQGHVDAPLARSSVNRQKMAIVSDGRGKRAVTHYRMI-----------TPLKNASLIECRLETGRTHQVRVHMSSIGHSLLGDPVYGRsKKAHHALLQSLAFQRQALHAAHLGFIHPISGKQVDFDAEMPQDMQLLFK----------------------------
>UniRef50_C8QZ10(96-318:324) Pseudouridine synthase n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8QZ10_9DELT  E=1e-60 s/c=1.05 id=33% cov=84%
----LYEDEDILVLVKPPGLVVHPADGHRQGTLVHGLLHHCRnlsgisGQLRPGIVHRLDKDTSGCLVVAKNDLAHHNLVQQFKGREVEKTYQALLRGILAEDTGQVVLPIGRHPVHRKKMAVRREGGREAVTHWRVRQRF----------SAGYTLVELLLETGRTHQIRVHMAALGHPLAGDRLYG---RNPEKDMPYGIDRQWLHAWRLAFNHPRSGRRLTFTAPLWVDLQASLDRL--------------------------
>UniRef50_B8FLB4(83-316:321) Pseudouridine synthase n=2 Tax=Bacteria RepID=B8FLB4_DESAA   E=2e-60 s/c=1.00 id=33% cov=86%
-LAILYEDRDIVAVNKPPGMVVHPAPGHSSNTLVNALLAHCkdlsgiGGVQRPGIVHRLDKETSGVILAAKNDAAHAGLSEQLAQRRVEKFYLALAHGVIKeDTGVIDLPLARHPSDRKRMHVSTPAKGREALSLWTVKERF-----------LDATYVKVQIKTGRTHQIRVHLAALHHPVIGDTVYGGRKkrgrlPASVLGKAPPPERQMLHAHIVSFTHPVTGEKLTLTAPLPQDMAQLLEAL--------------------------
>UniRef50_A7NB61(88-310:332) Pseudouridine synthase n=18 Tax=Francisella RepID=A7NB61_FRATF   E=2e-60 s/c=1.05 id=25% cov=85%
-LKIIFEDDDIIVIDKPVNMIVHPGAGNPTGTVSNALLHRYKDQdklPRAGIVHRLDKDTSGLMVAAKSSIAYHNLVQQLAERKVSRKYLAIVEGEIYQQGTINQPIGRDPTNRTKMAIN--YRGKEAITYYTPIEVYD-----------GFTLIECQLETGRTHQIRVHMKSIKHPLVGDQTYNKSSTKLEKLAITIPTRQALHAYKLSFIHPTTAKMVKFKSKLPEDMLNLKAQL--------------------------
>UniRef50_A9BMW0(125-348:356) Pseudouridine synthase n=10 Tax=Comamonadaceae RepID=A9BMW0_DELAS   E=3e-60 s/c=1.04 id=30% cov=83%
-LDVVYEDEHLLVVNKPAGLVVHPAPGNWTGTLLNGLLGRDPKArevPRAGIVHRLDKDTSGLMVVARSRAAMDALVAMIAARDVSRQYLALAHKAwgPRKHREVDAPIGRDPRNRLRMAVVDlaQHAGKTARTDIDLLA-----------GNEEVSLVRCTLHTGRTHQIRVHMASLGHPLVADAVYGGKEAG-------GMARQALHAFRLAFTHPMTGQALVLRAPLPPDMAQALENWG-------------------------
>UniRef50_B8CWM0(82-306:308) Pseudouridine synthase n=1 Tax=Halothermothrix orenii H 168 RepID=B8CWM0_HALOH  E=5e-60 s/c=1.04 id=29% cov=83%
-LDIIYEDKDILVLNKNAGLVVHPAPGNHENTLVNALIAYCDnlstisGVNRPGIVHRLDKDTSGVMVIAKNDISHRKLVEQFKQRKTKKYYRTLLKGELPYKEGKIDAPIGRDPHDRKKMAVTRKNSKKAVTYFKVLEFFR-----------DHSYVEVELKTGRTHQIRVHFSYMGFPVVGDSIYGKKR------NRLQATRQLLHAYRLGFYHPRNDKWVEYKASLPDDFKKALD----------------------------
>UniRef50_Q312A0(119-368:578) Pseudouridine synthase, RluD n=6 Tax=Bacteria RepID=Q312A0_DESDG   E=7e-60 s/c=0.93 id=29% cov=93%
-LEVLYRDAHMLVINKPAGLTVHPAPSCPEGTLVHRLLHHFpeleaQEGFRPGIVHRIDKDTSGLLLIALTEKARLALSDAFAGRRIHKEYLALVKGIPEgDSGEIDAPVGRHPTHKTRMAVV--RGGREALSTWRVL-----LADPHGGGGTGWTLVAVRIHTGRTHQIRVHMQHTGHPLWGDALYGGMPGREELQTTPALaqtaTRQMLHAWKISFDHPVTGAPMQFTLPPPADFGTLIRDLG--------SRCQRVVITGMPG----
>UniRef50_D0MJ49(86-350:355) Pseudouridine synthase n=2 Tax=Bacteria RepID=D0MJ49_RHOM4   E=2e-59 s/c=0.87 id=30% cov=86%
-LDIVYEDPYLIVVNKQAGLVVHPARGNRSGTLVNALLYyigsgpvrfdeeddlpeddeiglsmvstgpteAKLEAPRPGIVHRLDKDTTGLIVVAKDDVTHTGLARQFEHRTIARTYLAIVWGVPdPPRGRIEAAIGRDPRDRQRMAVVPDDRGKRAVTHYEVVEALPA-----------AALVRFKLETGRTHQIRVHARHIGHPVLGDPTYGGRTIRYGPHTPRrrafydqlfaRLTRQALHAHTLGFRHPRTGEWLEFEAPLPEDMACALEQL--------------------------
>UniRef50_A0L9J0(87-327:332) Pseudouridine synthase n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L9J0_MAGSM  E=3e-59 s/c=0.95 id=30% cov=86%
-LEILFEDEHLIVLNKPAGMVVHPGAGVNHGTLVNALLYHCGTPDNPHgglsgiggvirpgIVHRLDKETSGIMVAAKQDHAHIHLSRQFEQRTIGRRYLALTRGIPQPAQGRIEGAIGRHPIHRTKMAVVEQGGRAAATRYKVLE-----------PLGQFALIRCRLESGRTHQIRVHMTHIGHPLVGDPLYGAQHKAPSHWPPLHrqrfdqFQRQALHAHTLTFIHPHTGEEMSFKRPPPADFRQLYETL--------------------------
>UniRef50_Q2W2D5(265-502:505) Pseudouridine synthase n=39 Tax=Bacteria RepID=Q2W2D5_MAGSA   E=3e-59 s/c=0.97 id=30% cov=83%
-LTVVYEDEDLIVIDKPAGMVVHPAPGNPDETLVNALLAHCGESlagiggvKRPGIVHRIDKDTSGLLVAAKTDAAHRGLATQFAAHTLERAYWALVWGTPSPRQGEIEGNIGRNPNDRKKMAVVKSGGKPALTRYRVLKSF---------AGGAVSLVECRLATGRTHQIRVHMTTQGHPLVGDPVYGRIRGHKGvvlppevKTALIQFPRQALHAYLLGFSHPTKGYDVRFESGMP------------------------------------
>UniRef50_A7HM17(79-304:314) Pseudouridine synthase n=2 Tax=Thermotogaceae RepID=A7HM17_FERNB   E=5e-59 s/c=1.02 id=29% cov=85%
-LDIIYEDRDILVINKQPGIITHPIPSHTSGTIVNGVLYHCKDLQgiggvlRPGIVHRLDKDTSGVMVIAKNDLAHQSLTKQFKDRLTEKLYICLVKGVPKRKeGDIEINIARNPVLRVKMTVTNSEYGKPALTHYKVVREF----------GDIAALVFAYPKTGRTHQIRVHMKYIGHPLMGDEVYGRAKED----EIFGIKRQMLHALSLSFYHPRTGEKVKFIAKIPQDFKEAIQKL--------------------------
>UniRef50_C0QAZ3(81-310:313) RluD1 n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QAZ3_DESAH  E=2e-58 s/c=0.99 id=30% cov=86%
-LDFLHEDQWIVVVNKPAGMVVHPGAGNSSGTLLNALLHHFPsltdthcdPPLRGGIVHRLDKDTSGTIVVAKSKKAYEFLQKEFRFRRVEKRYIALATGIITETQGRITLPIGRHPIHRKRMAVNTERARPAETLWRVLGQM-----------AGHTLLDVGLKTGRTHQIRVHFRALGHPLAGDRVYGFR-----GKQSARAPRQMLHAGTLGFRHPWSGKRVEFTAPLPEDMVEVLERLN-RGPL--------------------
>UniRef50_B8GZR6(103-335:342) Pseudouridine synthase n=2 Tax=Caulobacter vibrioides RepID=B8GZR6_CAUCN  E=5e-58 s/c=0.97 id=31% cov=85%
-LSILYEDAHLIVVDKAAGMAVHPAPGTYNGTLVNALLHHCgaslsgvGGVARPGIVHRLDKDTSGVMVAAKSDAAHRGLSTLFATHDIDRLYVALTRGAPNPPTGTIQTQIGRSPGDRKKMAVLRAGGREAITHYRVEAAFGPADRPL------AARVACRLETGRTHQIRVHMASKGSPCLGDPVYGAAQPAAAVRERIeaaGLRRQALHAAVLGFVHPITGETLRFETPLPADM---------------------------------
>UniRef50_B1I3F8(81-302:309) Pseudouridine synthase n=2 Tax=Bacteria RepID=B1I3F8_DESAP   E=5e-58 s/c=1.02 id=32% cov=83%
-LEVCFEDPDVLVVNKPRGLVVHPAVGHYSGTLVNALLHHCRdlsginGILRPGIVHRLDRDTSGLLMVAKNDAAHLALAGQLKDRAVLRRYTALVHGRPRRETGTVDAPIGRHPRDRQRMAVTPRSGRAARTHYRVVRRFD-----------KFSLLELTLDTGRTHQIRVHMAHVGHPLVGDLKYGHARP------ELGLEGQFLHAGTLGFRHPRTGEVLVFEAPLPSELAAVLERL--------------------------
>UniRef50_B8J173(80-318:525) Pseudouridine synthase, RluA family n=2 Tax=Desulfovibrio RepID=B8J173_DESDA  E=6e-58 s/c=0.95 id=32% cov=90%
-LELLWQDDHLVVCNKPAGLTVHPCPSCPEQTLVQRLLGRFPqlsrlEGQRPGIVHRLDKDTSGLLVVALTEADCLALAAAFAERQVHKEYLALVSGLPPLEGQCREPLGRHPTAKIKMAVVpEDQGGRNAFTEWRRLWNTD---------DGSVSLLAVRIHTGRTHQIRVHMTHLGYPLLGDRLYAPKAVQNM------APRQMLHAWRLGFTHPASGEDMRFTCPPPHDMPDA--------ALAAMQRMQRLVITGNPG----
>UniRef50_C9LM35(80-300:308) Pseudouridine synthase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LM35_9FIRM  E=8e-58 s/c=1.02 id=29% cov=83%
-LDILYEDNDMIVINKRRGVVVHPGAGNTEGTLVNALLFHCGEqlrsvgdPERPGIVHRLDKDTSGVMVAAKSERAYGILQKEIASHKAQRCYIALVHGQMEGDTGVIRLPLGRSTKDRMKWDVLHETGRPAVTHFHVIEYL-----------PHYSWIECKLETGRTHQIRVHMAHIRHAVVNDPLYGWKK------DHFPIKGQALHSHTLELCHPITGEVMHFEAPVPEDMINCLN----------------------------
>UniRef50_B6BTN1(84-312:346) Pseudouridine synthase n=2 Tax=Betaproteobacteria RepID=B6BTN1_9PROT  E=8e-58 s/c=0.98 id=26% cov=85%
-LDIVYEDDDILVLNKPYNLVVHPGSGNANGTLLNGLLYYNKDLEKLprgGIVHRLDKDTTGLMVVAKNEESQNNLISQLQSKSVYREYRAIVWGQIWQNKVIQKPIGRHP-RQRTKMAVTKVNGKDAETKLEILERFNY-----------HTYVRCLLKTGRTHQIRVHMLDNNSPIVGDKDYGLKKIIPTKNMEMDLlksiknfDRQALHAIALGLIHPKTNKEMKWTIDLPEDMKELLS----------------------------
>UniRef50_Q0BWH2(81-335:341) Pseudouridine synthase n=3 Tax=Alphaproteobacteria RepID=Q0BWH2_HYPNA  E=8e-58 s/c=0.88 id=31% cov=89%
-LEILFEDAHLVILNKAAGMAVHPAPGSQTGTLVNALLHHCQGQlsgiggvERPGIVHRLDKLTSGVMVAAKTESAHTGLAALFERHDIDRVYRAVTRGAPrPLSGTIEAAIARSESDRKKMSVHrnpDSPAARHAVTHYKAVETFGYKDRATRLPA--AALLECRLETGRTHQIRVHMAHSGAPLIGDPVYGRQagimawkapgseaRYDKALAAARAFSRQALHAAVLGFVHPITGETLRYEAPLPEDMTGLIAAL--------------------------
>UniRef50_B3DV48(91-325:325) Pseudouridine synthase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DV48_METI4  E=1e-57 s/c=0.96 id=29% cov=88%
-LEILYEDEEILIVNKQRGMVVHPSCGHWSGTLVNSLLFHYGESlpgsslLRPGIVHRLDKDTSGVMVIAKTERSLKSLLLQFSQRTVQKVYLCLCKNRFPYLRYSFEANIHRHASDRKKMAVHRLKGKTAETRFTLL-----------FASSQASFLKCEPVSGRTHQIRVHLSHLGFPIIGDPLYGKGVRKYPF-------PLLLHAYALKIEHPRSGKKIEFMAPLPQDFKEALDFFYGRNFSWEENALSL------------
>UniRef50_C5TPY8(27-259:264) Pseudouridine synthase n=6 Tax=Proteobacteria RepID=C5TPY8_NEIFL   E=6e-57 s/c=0.96 id=55% cov=90%
MLDIIHRDSRTIAVNKPAGMLVHRSWLDKHETRFAVQTLRDQIGQHVYPVHRLDRPTSGVLLFALDTEAARLLTQQFENKTIEKTYWAIVRGYLPSDGLIDYALKYMPDKIAE--AQTEATLQEAQTAYRCLAQTELPFQSAlRYPTSRYSWAELTPYTGRKHQLRRHMKHIFHPIVGDTNYGDLRQNHAVAEHIGTQRLMLHARSLSFQSIEDGSRITVNAPTDNDWRLWMEKF--------------------------
>UniRef50_C6BSG2(94-339:549) Pseudouridine synthase, RluA family n=1 Tax=Desulfovibrio salexigens DSM 2638 RepID=C6BSG2_DESAD  E=2e-56 s/c=0.90 id=29% cov=92%
-LEIIYNDGKIAVINKPAGLTTHPAPSCPTGTLVhrmihHFPEIRDMDEWRPGIVHRLDKFTSGLITVALNEHDRLAMSTAFADREVNKAYLAIVHGVPKREFGEIDQPMGRHPVHKTKMAVVLKGGRDARSEYEVLWS---------DPAGRASLVKVKIYTGRTHQIRVHMAHIGHPLVGDQVYGSMPHAIWEQDQPQLaklaERQMLHAYSLSFTHPDSEEELSFTQAPPEDFINMLKAL--------DKSVQRVGLIGMP-----
>UniRef50_A4WSV2(90-337:349) Pseudouridine synthase n=41 Tax=Alphaproteobacteria RepID=A4WSV2_RHOS5  E=2e-56 s/c=0.89 id=31% cov=84%
-LSVVWEDADLIVIDKPVGMVVHPAPGQWTGTLVNALLHHCgaslsgiGGEKRPGIVHRIDKDTSGLLVVAKTDRAHQGLAAQFEAHTVERRYLALVHGVPepsdprlrgirgvsfePGGVLRIATGIARHRTDRQRQAVTFEGGRHAVTRARLLERFGTPPA--------AALVECRLETGRTHQIRVHMSHVGHGLIGDQTYGGRRKLSAKAvgaeaaqAAEAFPRQALHAATLGFCHPVTGEDLSFESPLPADM---------------------------------
>UniRef50_D2BIX0(80-298:302) Pseudouridine synthase n=5 Tax=Dehalococcoides RepID=D2BIX0_DEHSV   E=2e-56 s/c=1.01 id=31% cov=81%
-LEIIFQDKDLLLINKPPGLTVHPAPGHPDHTLINGVLALEPkmedfdDPLRPGIVHRLDKDTSGLLLVAKNRETLANLSAQFKERTVRKYYLTLVKGELhPAEGFIEAPLGRDPQNRQKIAVV--SNGRHARTGYKVLRYIQ-----------GYSLLEVKLETGRTHQIRVHFAAIGHPVAGDAIYGQKETW--------LKRQFLHAHRLSFTLPSNGQTVEFTSPLPPDLEETLK----------------------------
>UniRef50_Q1ILA4(82-332:333) Pseudouridine synthase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=Q1ILA4_ACIBL  E=9e-56 s/c=0.87 id=29% cov=89%
-LDVVYEDDDLAVINKPAGMMVHVGAGATEeernrGTLVNALLYRFralsevGGDMRPGIVHRLDKETSGLIVVAKNDVAHRKLAEQFSSRRVHKKYVALVHGWPKKLKGTINLPIARDMSRRTRMTTRGSGGRDALSHYEVKEKIESPY-------GKFALVEVKIETGRTHQIRVHMASLGHPVVGDTLYGAPGELRVTKALKGMPskmasleRNFLHAAEIELQQPATGKALRFVTKVPaalEDFAETLRHPEVRG----------------------
>UniRef50_D1PCC3(131-376:387) Pseudouridine synthase n=1 Tax=Prevotella copri DSM 18205 RepID=D1PCC3_9BACT  E=1e-55 s/c=0.89 id=28% cov=87%
-INVVYEDDQLMVVNKEAGMVVHPGAGNFHGTLiqAVAWHLRDMPefdanDPEVGLVHRIDKDTSGLLVVAKTPTAKNALGKQFFNKTTHRSYNALVWGNIVEDEGRIEGNIGRDPKNRLRMKVFDPDsgiGKTAVTHYKVLERFGY-----------TTLVQCVLETGRTHQIRAHMKHIGHPLFMDETYGGTEILRGQRSSsykafiqncfKLCPRQALHAKTLGFVHPTTKQQMDFDSEWPNDFRQLIEK--WRGFI--------------------
>UniRef50_Q13E92(178-422:426) Pseudouridine synthase n=28 Tax=Alphaproteobacteria RepID=Q13E92_RHOPS  E=6e-55 s/c=0.88 id=30% cov=86%
-LEIVHEDDDIIVIDKPRGLVVHPAAGHETGTLVNALIAHCGESlsgiggvRRPGIVHRLDKDTTGLMVAAKNDRAHQSLSAQFADHgrtgELRRGYYAFVWGAPNRIRGTIDAPIDRHPHAREKMAVRD-GGREAITHWEVLETFT-----GRSGGEIVSLIACQLETGRTHQIRVHLAHIGHPLLGDDVYGPHFKTKasqlrpdARAALTDLGRQALHAYLLVLEHPSTGEVVAWESGLPADLKRL------------------------------
>UniRef50_C7H7W3(80-308:314) Ribosomal large subunit pseudouridine synthase D n=2 Tax=Faecalibacterium prausnitzii RepID=C7H7W3_9FIRM  E=7e-55 s/c=0.94 id=30% cov=85%
-LDIIYEDAHLLVVNKPKGMVVHPAPGNPDGTLVNALLWHCkgslsgiGGEIRPGIVHRVDKDTSGLLVVAKDDATHIGLSQQMAVHSVERAYNTIVYGGFAQDEGFVESNLGRSKTDRKKMAVypaSEPHTKYAYTGYKVLERL-----------GEFTMLECRLKTGRTHQIRVHMASIHHPVAGDPVYGPHNCITS------LHGQCLHAKTLGFIHPITGEHLRFDSELPDYFTRFLTTLRQR-----------------------
>UniRef50_P54604(83-300:302) Uncharacterized RNA pseudouridine synthase yhcT n=5 Tax=Bacillus RepID=YHCT_BACSU  E=2e-54 s/c=0.98 id=33% cov=82%
-LDILFEDNHMLIINKPAGIATHPNEDGQTGTLANLIAYHYQINGEtckVRHVHRLDQDTSGAIVFAKHRLAHAILDQQLEKKTLKRTYTAIAEGKLrTKKGTINSPIGRDRSHPTRR--RVSPGGQTAVTHFKVMAS---------NAKERLSLVELELETGRTHQIRVHLASLGHPLTGDSLYGGG--------SKLLNRQALHANKVQAVHPITDELIVAEAPFPADMKNLC-----------------------------
>UniRef50_A6NQQ9(84-296:300) Pseudouridine synthase n=1 Tax=Bacteroides capillosus ATCC 29799 RepID=A6NQQ9_9BACE  E=4e-54 s/c=1.00 id=36% cov=81%
-LDIVYQDQDVLVLNKAPGVAVHPGPGHYSDTIgnfLMDYYRKQGILADFHPVHRLDRGTSGLLLVALHGHAQEVLKEQLHSPSFRRVYLAVCEGAPnPPSGVIDAPIGRLEGSVLARTVRPD--GQRAVTHYRTLRTV-----------NDRALVRLELETGRTHQIRVHMAHLGHPLTGDFLYGTEDQS-------LIPRPALHAAELSFTHPITGKTMAFTAPLPQDMAAL------------------------------
>UniRef50_A4RT55(70-332:332) Predicted protein (Fragment) n=3 Tax=Chlorophyta RepID=A4RT55_OSTLU   E=5e-54 s/c=0.81 id=29% cov=84%
-LDIVHEDESVLVVNKAAGMVTHPSAGHESGTLVNAVLGHCDLPElvvptgnqalsdddeddedavdedegardgmiRPGIVHRLDKGTSGVMVVAKDASAHNSLCEQFAARVVRRKYVAILSGVPSPSKGRIEAPIGRDPRDRLRMAVTQGGGRFAASNYEVIATL---------ANGNASLVEWRLETGRTHQIRVHAKHIGHPILGDDtygggggaavsalsRYGVFDVKEAKALMSTIDRPMLHARTLGFTHPQSGEALDFSRDPPEDF---------------------------------
>UniRef50_Q8ZQ16(95-315:319) Ribosomal large subunit pseudouridine synthase C n=110 Tax=Gammaproteobacteria RepID=RLUC_SALTY  E=8e-54 s/c=0.96 id=34% cov=84%
---ILYEDDHILVLNKPSGTAVHGGSGLSFGVIEGLRALR-PEARFLELVHRLDRDTSGVLLVAKKRSALRSLHEQLREKGMQKDYLALVRGqWQSHVKTVQAPLLKNILQSGERIVRVSQEGKPSETRFKVEERYAF-----------ATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDQQLTEAgTGLKRLFLHAAALKFTHPGTGEVMRIEAPMDNALKRCLQ----------------------------
>UniRef50_Q31IZ8(10-246:252) Pseudouridine synthase n=2 Tax=Proteobacteria RepID=Q31IZ8_THICR   E=9e-54 s/c=0.89 id=48% cov=91%
-FKILYQDDSLVAVHKPAGLLVHRSPIDRHETQFAVQMTRDQINQKVYPLHRLDKATSGLLLFALDSNTARLMGQQFEEHTIQKHYLAICRGWTAEHGEIDHALKHKLDKLGDRHAQTNKPPQEALTNFERLATTDVMHKIGKFDSQRYSLVKLMPKTGRKHQLRRHLNHISHPIIGDVKYGDRHHNHFFNTWLGQHRLYLAATSLTFNHPQTNARMTLNAPLELSYQKATQHLNWQ-----------------------
>UniRef50_Q01Q94(77-296:296) Pseudouridine synthase n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q01Q94_SOLUE  E=2e-53 s/c=0.96 id=33% cov=82%
-LRILYEDADVVAIDKPAGMVVHAGAGVHSGTLVNALLHRFatlsgvGGPLRPGIVHRLDRFTSGVLLVAKNDAAHQKLAAQFSGREIEKVYLALVHGTVKPETGRIERPIARDPVHRARMTARLAEGRAAWSEYRVLRRF-----------PDFTLLEVRIGTGRTHQIRVHLASIRHPVVGDTLYGAPAQ-------PLLGRYFLHAHRIRFHLP-SGREMLIESPLPPDLEAWL-----------------------------
>UniRef50_A3DDK9(79-316:318) Pseudouridine synthase, RluA family n=3 Tax=Clostridium thermocellum RepID=A3DDK9_CLOTH  E=4e-53 s/c=0.88 id=29% cov=84%
-IDIIYEDEFLIALNKQPGIVVHPTCSHPGGTLanaVAFHLQKKGIVKKIRPVIRLDRDTSGIIIFAKNPYCQEFLIRQMNDKTFIKEYIGIVHKVLENdNGTIDLPIARKPGSIMLRHI--SPDGDPAVTHYTVLERL-----------NGATLVKFRLETGRTHQIRVHCQAIGHPLLGDTLYPFEDtpyslsgnnphitqANTPSITSGIITRQALHSQRAVFLHPFTKKILEITAPIPEDMKSALE----------------------------
>UniRef50_Q6MGX8(69-318:319) Pseudouridine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MGX8_BDEBA  E=4e-53 s/c=0.84 id=26% cov=86%
-LDVLFEDEDLIVINKPAGLVVHPAAGHAHDTLVNALIHHtddlsmKFGEERPGIVHRLDKETSGIIVIAKNDKAHESLTSQFKERSTHRIYYAVCLGTARTlSGSVRSFLARHPVDRKRYASVLGDDrkpltdpnddpglGKWAVTHFEVLQR-----------KSGMSYLKLKLETGRTHQIRVHMSESGLPIAGDTLYGADRKIKSIEARatqedlRTLPRFLLHAAELGFTHPRTKERMFFTKDWPEDVLVLIKKWG-------------------------
>UniRef50_A7H6D3(87-332:339) Pseudouridine synthase n=6 Tax=Cystobacterineae RepID=A7H6D3_ANADF   E=5e-53 s/c=0.85 id=32% cov=92%
---VLHEDADVLAVDKPAGLAAHPGTGISGATLVEMARAHLGTPAdlpptefKPSPAHRLDRDTSGVVLVAKNRKTMVRLTELFTDGaDVKKTYLALVKGKMPREAGTIDLPLAEHEQTARSKAARGVNLQEALTRWKVVSAMK-----------EASLLAVTIETGRTHQIRRHLEAVGHPVLGDRRYGDFPTNRAARQRWGLRRMFLHAWRLELPHPTTGAPLRLEAPLPGELLEALSRANLSS--PAGTASGRAAPRGA------
>UniRef50_Q47Y03(20-301:304) Pseudouridine synthase n=1 Tax=Colwellia psychrerythraea 34H RepID=Q47Y03_COLP3  E=5e-53 s/c=0.74 id=47% cov=91%
VLDILYQDEYMVAVDKPAGLFVHRSYMDKDEIYFALQLVRDQVGQYVYPVHRLDRPTSGVLLFALTKDVATKLSEAFANKSsqaefksdtelegkvhdktqtgqqgqqsmteglttdknidgsdlaMVKTYYALARGHLAVPVdLIDHPLKEKLDKLGDKNVSRDKPAQSAQSYYQVKQQASLPIKVGKFDSVRYSLIEVRPITGRRHQIRRHLAHLRHPILGDINYGDNKQNPFFIEHFGFKRLMLIAKSLEFNHPINNDRIKISAPFDEQWQQVFTTFEW------------------------
>UniRef50_C6J6E3(85-312:321) Pseudouridine synthase n=2 Tax=Bacillales RepID=C6J6E3_9BACL   E=6e-53 s/c=0.92 id=29% cov=83%
-FDIVYEDEALLIVNKAAGLIVHPTHGHYTGTLangVVYYWQEKGEKFRFRPVHRLDQETSGLIAIAKNAYVHQHISEQLIAGEVTKKYTALVHGCPAvPEGTIDGPIDRDPAEPHRRIVT--PSGYPSLTYYKVAEAY-----------GDGARVELRLGTGRTHQIRVHMTSIGHPLIGDKFYGmpglaelpAPARERIARLDAAIGRQALHASELGFRHPLTGEALTFKSELPEDMLKL------------------------------
>UniRef50_C0QPR5(85-318:319) Pseudouridine synthase n=4 Tax=Hydrogenothermaceae RepID=C0QPR5_PERMH  E=6e-53 s/c=0.89 id=25% cov=86%
-VDILFEDEDIAVVYKPAGMVVHPSPGHTSGTLVNALLYHfrniseYGGKERAGIVHRLDKDTAGLMIIAKSEFAHKELQKQFQERTVDKRYIAVVTGIVQNDHGFIDLPIGRSIYNRKKMGTEATNLRDALTEYWV---------KNRSEKENLTVVDIKLHTGRTHQIRVHFSAIGHPLFNDKVYGFKKSQLRSEKMRSISDQtlyhALLAYRIAFDHPRTGEKIDITLQkLPEHISKVIE----------------------------
>UniRef50_B1ZYX0(80-305:311) Pseudouridine synthase n=4 Tax=Verrucomicrobia RepID=B1ZYX0_OPITP   E=6e-53 s/c=0.92 id=30% cov=85%
-LTVLFEDKHMLAVNKAAGMVVHPGVATSEDTLVHALLAHCagslsgiGGVERPGIVHRLDKETTGVIVVAKTDAAHRALADQFATRTLKKEYVALVAGVPRLLSGSIDRAIARHPVHRHRMTV-GEGGRPARTDWELVEAFGDIG----------ALVRCRIFTGRTHQIRVHLKSLGHPILGDALYGWKPEPRLATQPA---RVMLHAEHLVLTHPISGKELDLRAPLPKDFVAMIKEL--------------------------
>UniRef50_C9M5C8(49-273:276) Pseudouridine synthase n=1 Tax=Jonquetella anthropi E3_33 E1 RepID=C9M5C8_9BACT  E=8e-53 s/c=0.93 id=33% cov=84%
-LDVLYRSDSVLVINKPAGLLSQPDTKGEDSVATRALGYASDPAFGAQLVHRLDRNTSGVMILALDGQALRSLMVCFKERTANKTYLALVSGQLPPSGQIDAPLLKDPD---KKLVRVASNGERAVTRFRRLAT-----------DGQFSLAEVEILTGRTHQIRVHMNHIGHPILGDAKYGDFSAKPQVR-RLGIRRPMLHATCLVVNSPddclkeISGRR--FDAPLAADMASVCQKLGF------------------------
>UniRef50_C6CWL6(89-309:316) Pseudouridine synthase n=2 Tax=Paenibacillus RepID=C6CWL6_PAESJ   E=2e-52 s/c=0.94 id=29% cov=84%
-LSIVFEDDYLLVVNKPAGIIVHPTKGHYTNTLANGIVHHwqvRGERVRFRPVHRLDEDTSGLVVIAKNPYIHQQLSEQLQAGTIMKIYCAYVYGTPsPADGTVGAPIDRNPEDPHVRIVTPE--GYPSVTHYKTAAVF---------GGGQASKVRLKLETGRTHQIRVHMKHIGCPLIGDGMYG-LQTGKVDEWETAAGRQALHAETLGLTHPMTKEWSEWTAALPPDLVQL------------------------------
>UniRef50_Q2GGY1(96-332:337) Pseudouridine synthase n=13 Tax=Rickettsiales RepID=Q2GGY1_EHRCR   E=2e-52 s/c=0.88 id=22% cov=86%
-ISVVYEDHDIIIINKAPGITVHPGAGTNNNTLVNALVAHYGNslshvgkATRPGIIHRLDKDTSGLMVIAKNEKSYYFLSDLLLKKQIKKEYLAVVWGLPNPKSNTIKNYICVKPNNKQMMTVTHlpHKGKLAITEYQTQKSF----------SNIASLIKCRIHTGRTHQIRVHMSYIGNSIIGDQKYGKNNSKSVKYAKQStiintLKRQALHAYKLGFTHPTSNTYIEFHSYIPNDIQMLIDEL--------------------------
>UniRef50_C4XFS9(84-299:315) Pseudouridine synthase n=2 Tax=Mycoplasma RepID=C4XFS9_MYCFE   E=3e-52 s/c=0.96 id=28% cov=81%
-LDIKYEDDDLVIINKPSNLVVHPSPGHYNDTLVNGLLYHFKNNlsnenglLRPGIVHRIDKDTSGLLIIAKNNKMHNSLTDMLKRHEIERSYLAIVRGLIENPLTKINLPIARNTVDRKMMSVHKE-GKEAITFVHLLKHF-------YLDKEPMSLVRCELKTGRTHQIRVHLSYIKHPVYGDPTYGKSVDEFN---------QRLHAYKLKFIHPLTKKEICVYAPVPKEF---------------------------------
>UniRef50_A5INM9(85-295:304) Pseudouridine synthase n=7 Tax=Thermotogaceae RepID=A5INM9_THEP1   E=3e-52 s/c=0.98 id=31% cov=79%
-LDVLYEGKHYLVLNKPPNIAIHPGKGVHVATLiEGLLHYGQEKGFSPFLVHRLDKDTSGLLVVAKDREAARILTELFKDRNIEKEYVTLVRGTPENNMKITIPL----------------DGQEAISEIVSVKSLR-----------DVSLLRVKIHTGRKHQIRRHLSQIGFPVVGDDTYGDRHFNREFRKRYGLKRLFLHSYRMKFIDPWTEEEKDFRAPLPDDLLSVLN----------------------------
>UniRef50_P59838(86-318:321) Ribosomal large subunit pseudouridine synthase D n=3 Tax=Gammaproteobacteria RepID=RLUD_BLOFL  E=8e-52 s/c=0.88 id=26% cov=85%
-LNIIYEDNDILVINKASNMVVHPGIGHYQGTVLNALLYRYpsilKISKQAGIVQRLDKDTTGLMIIAKTVSAYDNLLRSFKLRKVVKEYDAIVYGKFTSNAGVVNQPMRRHFAKRTFMSV-HYTGKSAVTYYSVVEEFKA-----------HSRVRINLKTGRTHQIRVHMAYINHPLVGDQKYKGnfsvfdikKMSDELNNYLLDFNRQALHACTLQLLHPITQVQMKWNAPLPQDILQLIA----------------------------
>UniRef50_C0ZCK6(87-301:302) Pseudouridine synthase n=1 Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZCK6_BREBN  E=1e-51 s/c=0.95 id=33% cov=79%
--EILYEDDHLLIVNKPVGLLLHPTERYHHVTLDHLvsgHFFRTGLEAKVRHVHRLDQDTSGVVLYAKHPWASALLDEMLRERTIKRTYVAYVSGqMPKERGKINEPIGKDRNHGTRR--RVTPNGDPAITHYQVKERFQT-----------ATKVECQLETGRTHQIRVHFSHIGHPLLGDELYGGKRE--------LIKRQALHAAVLKFEHPFGGEVIEVTAPLPLDL---------------------------------
>UniRef50_C7MN62(82-319:347) Pseudouridine synthase n=8 Tax=Coriobacteriaceae RepID=C7MN62_CRYCD   E=1e-51 s/c=0.86 id=26% cov=88%
-LDVRFEDRWMMAISKQAGLCVHPAPGHEGGTLVNALIYAYgrdslahvQGDDRPGIVHRLDMDTSGLMMCAKDDTCGMALQDLVRDHKVDRRYLTLVHGNIAFDtGQIDEPIGRVGDDRLRMKISYRPTARNALTTFTVLERFE-----AGRADNGYTLLECRLYTGRTHQIRVHMEFIGHCCVGDPLY----RWGNEQVNLELSRQFLHSYSLSFNHPMTGDDIALVDGLPPDLFGALRSLEDRSM---------------------
>UniRef50_B0RLZ1(20-245:258) Pseudouridine synthase n=13 Tax=Xanthomonadaceae RepID=B0RLZ1_XANCB   E=1e-51 s/c=0.91 id=41% cov=87%
-LQILYQDAVLAVVDKPAGLMVHDSKLARGEDDFLADRLRVQLGRPIFLVHRLDRATSGCLLLAFDRDTASALGKALMAGEVEKDYLAICRGWPAEERFIVDHDLDGGPGKPIK--------KPAVTHFQRLATGELEIPSTGFATSRYALLRCQPQTGRFRQIRRHLKHLSHHMIGDTSHGDGRHNRSFRM-LGIHRMLLHAERLGFPHPADGRRISVVAPLDVEFAKACALFGW------------------------
>UniRef50_Q73K15(5-241:244) RNA pseudouridylate synthase family protein n=1 Tax=Treponema denticola RepID=Q73K15_TREDE  E=5e-51 s/c=0.86 id=30% cov=85%
--EILYEDKDILIVNKNAGLLVGADRWDseaPRLDKILEELYKDKGERKIYPVHRLDKETSGLIIYALNAEAHKTLNDDFQNRKIEKIYHAVSAGIPQEENFKAEEKLRIDGDKLHRTVIDEKKGKESLTEFSLLKRF-----------SRFCLLEARPITGRTHQIRAHLKHLGLPILCDNLYGNGEPvyisalkknwrGDKYEERPIISRLALHAHSLKFFHPISKEKIEISADYPKDMAGLINQL--------------------------
>UniRef50_C5S931(122-344:346) Pseudouridine synthase n=2 Tax=Gammaproteobacteria RepID=C5S931_CHRVI  E=5e-51 s/c=0.91 id=35% cov=85%
---IIHEDERLLVIDKPSGLAVHGGSGLSYGLIESLRQLR--PGRELELVHRLDRDTSGCLVVCKRRSALRELHALIREGGLDKRYLALILGELPRAElLVDAPLKKNVLSSGERLVRVDaQGGKEARTRFRRLKRFAI-------DGQALTLVEAELITGRTHQIRVHAAHLGTPLAGDDKYGDEAANQRL-KGYGLKRLFLHASALSFKLECMARPLRLECPLPDELQQVLDAL--------------------------
>UniRef50_D1W0M0(351-560:566) Pseudouridine synthase n=1 Tax=Prevotella timonensis CRIS 5C-B1 RepID=D1W0M0_9BACT  E=6e-51 s/c=0.97 id=34% cov=80%
-LHVVYEDDALIVVDKPAGILSVPGRSQRP-SVYSILRSQMPSSVELFSVHRLDMATSGLLILAKNSVVYRHLQRQFRTHHIQKEYIAILEGALSQREGVVTLPLRPDPFDRPRQVVDWEHGKKAVTSYRVL-----------NVRHGKTWVALFPETGRTHQLRMHCAHaegLNCPILGDPLYGHH-----------ANRLYLHATSITFEHPISGQLLTLHAQPPADFQDVF-----------------------------
>UniRef50_D1AV01(78-295:297) Pseudouridine synthase n=2 Tax=Bacteria RepID=D1AV01_STRM9   E=1e-50 s/c=0.93 id=29% cov=80%
----VYEDKYLAIINKYAGMVVHPSKGHEEDTLVNAIMYKIKdlsginGDLRPGIVHRLDKNTSGLIIIAKDDKTHFKLSEMFKNKEIKKIYYAIVKGKVNKKSGRIETMIGRNPNDRKKMAVVD-NGKLAITNFEVIDSNE-----------KFSLLKVDLETGRTHQIRVHLSHFFFPILGDSVYGRKDE---------YDRQMLHAYMLNFIHPITLEKIDVIGNFHSDFLRALS----------------------------
>UniRef50_A8IAL9(148-370:384) Pseudouridine synthase n=2 Tax=Xanthobacteraceae RepID=A8IAL9_AZOC5   E=2e-50 s/c=0.90 id=29% cov=85%
---ILFEDKDVLVLNKPSGIAVQGGSGTFRHIDGMLDALRAKDGQKPRLVHRIDKDTAGCLLIAKNRLSAAQLAKNFRSREARKIYWALVPGVPkPRQGRISTYLAREEAEERMRVARHgEEDASHAVTYYAVVEH----------AAQKMSWLSLKPVTGRTHQIRAHLAHIHHPIVGDPKYFNIENWELPGG--LQNRLHLLARRLVIPHPRGEGMIDVSAPLPPHMAQSWAVLGF------------------------
>UniRef50_A7VVQ2(79-295:298) Pseudouridine synthase n=1 Tax=Clostridium leptum DSM 753 RepID=A7VVQ2_9CLOT  E=3e-50 s/c=0.92 id=31% cov=80%
-VSVLWEDDALLILNKPPLMPVHPCPGHDRGTVCNfvsYYQKRKGEDWRFRPLNRLDKDTSGLVIGAKDSYTASALND------VGKTYFAVCQGSLPGEGVIDTPIRLKEGHSIQREA--GEGGKPAVTHWKSLAQ-------GAAAGKSYTLLALTLETGRTHQIRVHLSSIGHPLAGDDFYGGSRE--------LISRQALHCGLVELTHPFFLSRICVKAPFPNDFKKILE----------------------------
>UniRef50_C4PNG9(89-315:335) Ribosomal large subunit pseudouridine synthase D n=11 Tax=Chlamydiaceae RepID=C4PNG9_CHLTZ  E=4e-50 s/c=0.88 id=30% cov=83%
-LDKVYEDDMILVINKPRDMVVHPAPGHTQGTVVHALLHEigerlkqefPEEPWRPGIVHRLDKDTSGLLITVKTRRAKALYSELFATKQVKKLYVAICINAPSQELIH-TRIARHPLKRKEMTVlsTHAEGGKEAITHCHVLAT-----------NGRLSVVALYPETGRTHQLRVHMKHLGTPILGDPVYGIPSIN----FRYGLDKQQLHAYSLVFAHPESAERVKLVTKLPDDMTSLIEK---------------------------
>UniRef50_C5RBB6(79-293:305) 23S rRNA pseudouridylate synthase RluD n=1 Tax=Weissella paramesenteroides ATCC 33313 RepID=C5RBB6_WEIPA  E=5e-50 s/c=0.93 id=31% cov=81%
-IKILYEDENWLVVDKVAGVTSVPGKADRETTMVNrvkgYLISEGAEDLVPHVVTRLDRFTSGVALLAKHRFAHGLLDKQLQTHTVDKRYYAIVDGIvPDDHGFIDAPIGRMDNDFIRREVRAD--GRPSQTEYWVVNRM-----------PNQTLVKVQLHTGRTHQIRVHFKYIGHPLIGDEIYGGP-------MDRGIERQALHAYWLEFYDPFSEIKRHIQSPLPEDLKQIL-----------------------------
>UniRef50_A9GBV3(90-336:345) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GBV3_SORC5  E=1e-49 s/c=0.80 id=29% cov=86%
VIPVVYEDEHLLVIDKPAGLVVHPARGHASGTLVNGLLALPGfalapadprdpmGHVRPGIVHRLDRGTSGLLVVAKDEPTREALKDRFARHAIEREYAAIVAGE-ARDATYDTLHGRHPTDRLRFTSWIRGGagapgshvaaPRRAVTHVRVIERL----------GDAATVVACSLETGRTHQIRVHLAERGrTPVLGDPLYGKPPKKPAVRAiAEELGRQALHARVLGFIHPATQKPVRWESALPADMRKALDQL--------------------------
>UniRef50_A8F4Z7(86-292:294) Pseudouridine synthase n=2 Tax=Thermotogaceae RepID=A8F4Z7_THELT   E=1e-49 s/c=0.96 id=31% cov=79%
-LDILYEDDNLLILNKKAGITIHPSEKTRSTTLIqGLHFYGAKKGFKPHLVHRLDRDTSGVLVIAKNVKTARTLSHMFRNRLVKKEYITLVSGKIFGDGFIDKPL----------------DGSEALTEYKVLENFR-----------DTSLLRVILHTGRTHQIRKHFALIGNPVVGDILYGDKKVNELFKKKHNLRRQFLHCIRISFTNPSEPGVISIKAPLPDDLERVIK----------------------------
>UniRef50_B0T2G2(54-281:286) Pseudouridine synthase n=6 Tax=Caulobacteraceae RepID=B0T2G2_CAUSK   E=2e-49 s/c=0.87 id=30% cov=86%
---VIHEDDSVFVLNKPAGLSSQGGRIQAHTLDDLLWALARRDRPRPRLIHRLDRDTSGVILTARTKPAATFLGKALMGKRFRKTYWAIvTPGAPEPRGGQIDSPLRRESIGREAYMRvceaDHPDAETARSRYRTLAATE-----------GAALVELSPDTGRMHQLRVHMASIGRPIAGDSRYGG----ALMLGGAPVPRLMLHAANLVFPHPEGGER-RISAPIPDDMRAILAKLGLE--IPEQR----------------
>UniRef50_B0TDX6(83-311:339) Pseudouridine synthase, rlua family n=1 Tax=Heliobacterium modesticaldum Ice1 RepID=B0TDX6_HELMI  E=4e-49 s/c=0.86 id=28% cov=85%
-LKVLYEDADLLILDKPPGIEVHPPEQRARFRPTLAhgvahYFAEKGIKARVRPLHRLDKDTTGICVFAKNAFAHQALDRQLRNGSLQRGYLAILRGLPaELVGVIDAPIGRDPEHHMRRMVRDD--GERAITRYRvtqVIEPSGLEMKGAAESEGHWALAEVILETGRTHQIRVHFRHLGTPLLGDRLYGG--------DSPRIDRQALHSAWVTLLQPRSGEAVKVTAELPEDMARLL-----------------------------
>UniRef50_B1XXM0(119-338:369) Pseudouridine synthase n=6 Tax=Burkholderiales RepID=B1XXM0_LEPCP   E=5e-49 s/c=0.89 id=31% cov=81%
-LAVVHEDAHLLVIDKPAGLVVHPAAGHWSGTLLNgllAHHAAAAHLPRAGIVHRLDKDTSGLMLVAKSLQAHTALVRAIAARDVKREYLALVHGaVMDGLQVIDAPLGRDPVSRVRMAIVAS--GKPARTDVRRLAVAELPGDGVRqlpgatRAPRQVSAVHCQLHTGRTHQIRVHLASRGHPLLADAMYGG-------APAFGLQRQALHAARLHLLHPIDGRPLAFE----------------------------------------
>UniRef50_D1PYC1(93-306:306) Ribosomal large subunit pseudouridine synthase D n=8 Tax=Prevotella RepID=D1PYC1_9BACT  E=6e-49 s/c=0.92 id=28% cov=82%
-VKIVYEDAYIIVVEKNVGILSMPAGHHSLNVKAVLDEYFHKTKQPCqaHVVHRLDRDTSGLMIYAKDKKTEFSLQADWKGTVYDRRYVAVVSGVMEQDEGTIDSWLKDNKSYFSYSSSTDNGGKYAVTHFYTLDR-----------SPQHSLVEFKLDTGRKNQIRVHAADMGHPVCGDPKYGNGDD--------PIGRLCLHAYVLCFYHPVTHEPMEFQARIPQNFIQLF-----------------------------
>UniRef50_A6TSZ4(86-302:308) Pseudouridine synthase n=1 Tax=Alkaliphilus metalliredigens QYMF RepID=A6TSZ4_ALKMQ  E=6e-49 s/c=0.90 id=25% cov=80%
-FNVVYEDIDVIVINKEPGIVSHPTKSHPKDTIANAaqnYLEKKGVACRIRFVNRLDMDTSGLLVIAKNPYTHHIMSQQMKANEITKKYVAFVKGvVVANEGEIDGAIYRSSDETIKR--VVDDRGQQSLTKFTVLERY-----------ADATMLEVSLLTGRTHQIRVHMESIGHPMLGDHLYG-------YVDTELIRRQALHASYLSFLQPRYKEKIEVRASLPKDL---------------------------------
>UniRef50_P75485(80-299:309) Uncharacterized RNA pseudouridine synthase MG209 homolog n=2 Tax=Mycoplasma RepID=Y292_MYCPN  E=9e-49 s/c=0.89 id=28% cov=84%
-LDILYEDEQIMVVNKPNGLISHPTSFNESESLLGAALFHCNHQP-VFLVHRLDRDTSGVIMLAKNQSSLLHLQKQLQQRVMKRYYLALVHFPLDSLSGTISAPLERVGNNKVMWKVgnSSNKAKNAFTKFTVL-----------NQNEKAALIKCELLTGRTHQIRVHLQFIKHPVYNDPLYGLKSEQATEY------GQYLHAQQISFIHPTLNKEMGFEAQLDKTFSDKLDNLNLK-----------------------
>UniRef50_D2R760(379-603:603) Pseudouridine synthase, RluA family n=2 Tax=Planctomycetaceae RepID=D2R760_9PLAN  E=1e-48 s/c=0.87 id=28% cov=83%
-IRVVYEDEAIAVVHKPAPLPLHASGRFHRNTLE-WILREIYDPQKPRPVHRLDANTSGLVLFARTRHFAKLLQQQFTQGKVEKFYLALVSGHPVEDRFVSTAPISAEAGVFGSRSVDEEAGLPAETRFEVLARTTTA------DGKPVALVRCQPITGRTNQIRVHLWQLGHPIMGEQSYlADQKHGTTQTHTVDDPPLCLLAHQLSFQHPVSRERMTFTSQLP------------------------------------
>UniRef50_B0U5V6(104-330:330) Pseudouridine synthase n=7 Tax=Xylella fastidiosa RepID=B0U5V6_XYLFM  E=1e-48 s/c=0.86 id=32% cov=84%
---IVFEDARLLALNKPSGMASHGGSGVSYGVIEAMRILRPK--QELELVHRLDRDTSGLLIMAKKRAALIELQALMREasvngkegRGIAKRYLTLLSGRMPNgVMSVDAPLHINLRHGGERHVRVHHDGKPSKSRFRLLERR-----------GGQSYCEVLIETGRTHQIRVHAQHLGHPVTGDDKYGDQEVNRKLRDQIGLQRLFLHAVSLEFALDAGSTPYVLNAPLAEDLVAALDRL--------------------------
>UniRef50_A7HIF3(108-342:350) Pseudouridine synthase, RluA family n=6 Tax=Cystobacterineae RepID=A7HIF3_ANADF  E=2e-48 s/c=0.83 id=30% cov=85%
VFDVVHDDGALLVVDKPAGLPVHPTARYSANTFTSLARARFP-DRKVDPAHRLDRETSGLLACGSAPEWTSRMKRDFAQGRVKKTYLAIAEGAPrEDTFTVDAPLALTGASAVRVRMHVDAGGLASATDFEVLARR------VLAGGVPVALLACRPRTGRQHQIRAHLAHAGLPMVGDKIYGPDEnifdrftrhaLTDEDHARLRLPRHALHAWRLELPHPRTREPVGLESPLPPDLA--------------------------------
>UniRef50_D2RJC8(77-287:294) Pseudouridine synthase, RluA family n=2 Tax=Veillonellaceae RepID=D2RJC8_ACIFE  E=2e-48 s/c=0.92 id=31% cov=80%
-LSLLYEDEDLLVVDKPAGMLIHPTWSGARDTLVQAvggYFRRTGQHCGIHPLYRLDRDTTGVLMVAKSAFAKHALTR--DHSQIYREYLAVCEGRWGIPQGRIEHPIGRVAEGVDRWTV-RPDGRPAVTEYRILE-----------ENQEWTVLKIHLLTGRTHQIRVHFAHEGHPLVGDPLYGTKDG--------RIARQALHAWTVRFRHPRTGEEILLTAPMPGDMEGLL-----------------------------
>UniRef50_B6IQX5(100-324:336) Pseudouridine synthase n=1 Tax=Rhodospirillum centenum SW RepID=B6IQX5_RHOCS  E=2e-48 s/c=0.86 id=28% cov=85%
---VLFRDHDVIVLDKPAGLATQGGTNQVKHLDAMLDALKFEAEGRPKLVHRLDKDTSGCLVLARSAAAAAKLTAAFRSREARKIYWAVTVGVPkPMKGRIDLPVAKEAGTRGERMTVDEDEGVHAITYYTVLEH----------AHKQAAFVALWPRTGRTHQLRVHMAALGTPILGDGKYAGQGAFLEGAGDLPRQ-LHLHARRIILPHPRGG-VIDVTAPLPKHMRPAWDYFGF------------------------
>UniRef50_A1WTN6(11-248:249) Pseudouridine synthase n=2 Tax=Ectothiorhodospiraceae RepID=A1WTN6_HALHL  E=8e-48 s/c=0.81 id=43% cov=91%
-LAILYRDERLIAVYKPAGLLVHRSNIDRDRDVVLQRLRDQLGGHWVYPVHRLDRATAGVLVFGLDPDAASVLAAAFREQRIGKRYQAVVRGWVEAPGRIDRPLGAGRRGEG-------GAPQPAVTDYVPLAWTELPIPVSRYDTARFTRLALHPQTGRQHQLRRHMKAISHPILGDTTHGDGANNRFFREHFGARRLLLVATELVVPHPADGGAVRLATEPDAELQAIFRRAGLgEAPSPADE----------------
>UniRef50_B9JWI8(98-321:330) Pseudouridine synthase n=1 Tax=Agrobacterium vitis S4 RepID=B9JWI8_AGRVS  E=8e-48 s/c=0.86 id=31% cov=85%
----LHEDEKVFVLNKPAGLAVQGGSGLNRHIDQMLEAWTSKKGEKPRLVHRLDRDTSGVLVVARTRGAAQKLTAAFRERDTKKTYWALVKGVPRKHDdkisTWVVKEQTEDGDRMRIARHGEDGADHAVSYYRVLET----------AAQSLAWLEMEPYTGRTHQLRLHALHIGHPIIGDPKYYIDDPNWDFPGGVQ-KRLHLHARHIDIPHPDGG-RLRITAPLPPHMVQTWNLLG-------------------------
>UniRef50_D0LU78(110-350:369) Pseudouridine synthase n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LU78_HALO1  E=8e-48 s/c=0.80 id=30% cov=84%
---VLYSDPHMLVIDKPAGLPVHASARFYFNTLTRVLGERFP-GQPMQICHRLDRETSGALVVARGKPEAARLKGAFADKRAHKTYLALVWGDPPWPDGAWdsapeddaiidlpLGLVADESARIKIRMEVRAGALPSLTRVRVLERR-----------GRAALVRCLPLTGRQHQIRAHLAACGHPIVGDKLYAHGDDvfaaycdrgmTPELLERVRLPRQALHAAAIALPHPFEGRQVRAESPLPADMRAFLDR---------------------------
>UniRef50_B3QB01(219-442:455) Pseudouridine synthase n=3 Tax=Rhodopseudomonas palustris RepID=B3QB01_RHOPT  E=8e-48 s/c=0.86 id=29% cov=84%
----LFEDADVLVLNKPAGLAVQGGSGTTRHIDQMLEVLRDAKGQKPRLVHRIDKETAGCLLVAKTRFAATALTGSFRHRSARKIYWALVAGVPKPKQGRISTYLAKEesedDSIMRVAKHGDDGASHAVTYYAVVET----------SGQKLAWVSLKPVTGRTHQLRAHMAHIGHAIVGDPKYFNIENWQLPGG--LQNRLHLLARRIVIPHPRGG-VIDVSAPLPPHMLQSWNLLG-------------------------
>UniRef50_B6BTS8(86-306:306) Pseudouridine synthase n=2 Tax=Betaproteobacteria RepID=B6BTS8_9PROT  E=8e-48 s/c=0.87 id=29% cov=84%
--HIIYEDEWLLVVNKPSGLAVHGGSGIDFGLIEHMRHIKPEY-KFLELVHRIDKNTSGVIVIAKKRSALRSMQELFRNKKIKKNYLVAVKGNWDSKKKEVSLRLEKKQTSEGHHVNVVEDplrGKLSKSIFYLVKQMQKQ-----------SLLSAQIITGRTHQIRVQLAFLGFPVLGDDKYGDFALNKKL-QSSGLKRMFLHAHKLSFFHPFTEEKVELTADLPIELRKFFDE---------------------------
>UniRef50_Q03EW7(28-246:253) Pseudouridine synthase n=1 Tax=Pediococcus pentosaceus ATCC 25745 RepID=Q03EW7_PEDPA  E=1e-47 s/c=0.88 id=24% cov=83%
-IDVRYEDADYLIVNKPPFLPTVQSAANQKDTLVnrvkNYYVKNNYESRVVHVVTRLDQDTSGLVIFAKHRFAHTVMDQDLRQRKINKMYLTIVEGTFTnQHGIIETPIQRDPDSFIKRMVAPMGEGKPSLTEYWVEDTFK-----------NFTLLKVKLHSGRTHQIRVHFSSIGHPLVGDELYGGMANDI-------LQRQALHCFSLTFKNVFTEKMIDIKTSIPDDMLEYWNK---------------------------
>UniRef50_Q1D114(80-303:306) Pseudouridine synthase, RluA family n=6 Tax=Cystobacterineae RepID=Q1D114_MYXXD  E=4e-47 s/c=0.85 id=28% cov=84%
VLPVLHDDSALVIVNKPPGIVVEPEGRAASVVGLLAAQRPPFDVEglaQPGVVHRLDRETSGCLAFARTDTAAAALLRSFQEKRVDKRYWTLVLGQPPAQGRLEGPYARDPADPRRFTTRV-PSARRAALSFEVRERF-----------ADAALLEVDLDTGRTHQVRVQLSEAGFPVLADSLYG-PPEARAHAAARALGRQALHAFTLELPSPATGQPVRVEAPLPEDFQRAL-----------------------------
>UniRef50_A8Z5T0(101-335:337) Pseudouridine synthase n=3 Tax=Candidatus Sulcia muelleri RepID=A8Z5T0_SULMW  E=4e-47 s/c=0.81 id=23% cov=82%
-INIFYEDEYVIIINKQSGLVVHPGKGNESMTLINGLHFYFLKKKNIYnkipiLVHRIDKGTSGLILVAKDKNILEKIYKQFYINHIKRKYITLVWGYIKNNKGTIICNIGRSLKNRIYMNVFPNGiyGKFSITHYKVLERFKY-----------VTLLKCTLETGRTHQIRVHLKYIGHPILNDKDYGGNHTFKEKKNIKKLfinmKYQALHAYYIEYIHPIYRKKNYFICPIPD-----------------------------------
>UniRef50_Q73NS0(88-339:345) Ribosomal large subunit pseudouridine synthase, RluD subfamily n=1 Tax=Treponema denticola RepID=Q73NS0_TREDE  E=4e-47 s/c=0.75 id=25% cov=84%
-LNIIYEDENIIVVNKERGMVTHPAGGNWDGTLVNALNYYRLYDSRIkdefavelnkllsgevknieklslepyrmGIVHRLDKETSGLIITARNLKTEKLLKSFFKKRAVKKYYLAVLDGVPPKNKGRIKTSVFRSSSDRKKFSVsaDLSKGKKALSAYKVLKS-----------DGKMSLVLFRIYTGRTHQIRLHAKFMGCPVAGDKVYGKKKTGLEKKTGLAKKtgmPLMLHAYKLIIPDTVNSKK-EFKAPIPNDFKQIL-----------------------------
>UniRef50_Q489H0(364-562:567) Pseudouridine synthase n=3 Tax=Gammaproteobacteria RepID=Q489H0_COLP3  E=6e-47 s/c=0.95 id=39% cov=76%
-LEIVFQDEHVVVVNKPAGLLSVPGKSIKDSVYTRIKTQFPQASGGL-IVHRLDMATSGLLMLALNERAHKHLQQQFMNKEINKRYVATIEGKLEKTSGEICLPLRGDFDDRPKQMVCHEHGKYAETHWQLIEEVD-----------NTSKLFLYPITGRTHQLRMHCAHpdgLNLPIIGDSLYGHS-----------ADRLHLHAQRLSFTHPITKELLTFE----------------------------------------
>UniRef50_Q2W0L6(9-229:229) Pseudouridine synthase n=4 Tax=Alphaproteobacteria RepID=Q2W0L6_MAGSA  E=6e-47 s/c=0.86 id=27% cov=83%
---VLYKDQDVIVLDKPAGLAVHAGPNSPDHLELYLGALAFGWAEMPKLAHRLDRDTSGCLILGRHAKAIKRLGKMFEHRRVEKVYWSVSHGSPaADSGTVDAPLLKVSARGQGWRIKVDPAGQPSITDWSVLGRSD-----------GLSWIEWRPRTGRTHQIRIHAQYLGCPLLGDAYYGPDPEPKV--------RLHLLARAVAFPALApSKDPVRVTAPPPEHMVEALRRCGW------------------------
>UniRef50_Q63E77(85-302:307) Pseudouridine synthase n=73 Tax=Bacillaceae RepID=Q63E77_BACCZ   E=9e-47 s/c=0.87 id=25% cov=79%
-LHVVYEDDHVLIVNKPEKMDTHPSEKGGMGTLANLVAFHFQmqgLETKVRHIHRLDKDTTGGVVFAKHRIAGAIMDRLLMERKIKRTYAALVEGKVkKKQGTIDAAIGRDRHHATRR--RVSPKGDQAITYYKVEEYFK---------KQNVTLVTLQLETGRTHQIRVHMSYNGNPLVGDVLYGGGTKY--------MSRQALHAMKINFLHPITKEEIEVDVPFP------------------------------------
>UniRef50_Q8EWS1(72-297:298) Pseudouridine synthase n=1 Tax=Mycoplasma penetrans RepID=Q8EWS1_MYCPE  E=1e-46 s/c=0.83 id=23% cov=84%
-IEIVYEDKYILIVNKPNDIIVHPTSYDLSNTLANIIKYifdskkikYNGDPLRMGIVHRLDKCTEGLVIVAKSLDSFNAFTKLFLDQKIEKKYLALLHNHLQTRTVEVDAPIKRVETSTRREVSRDIDAKEARTIFKEINKYK-----------NFTLAEVELFTGRTHQIRVHAEFIKNHVINDPIYGPKHINKTTKY-----GQYLVAYKLKFIHPFTQKEVNINLDMPKEFKEYIKKYG-------------------------
>UniRef50_Q057H9(86-315:321) Pseudouridine synthase n=1 Tax=Buchnera aphidicola str. Cc (Cinara cedri) RepID=Q057H9_BUCCC  E=1e-46 s/c=0.82 id=23% cov=84%
-LNIIFEDSEILIINKPTNFVVHLGYGNTSGTLLNALIFHYPDNlliPRAGIVHRLDRNTTGILVVAKTISTYYFLINLFKKRKIIKEYDVIVIGRIEVDGKIEKPIKRDIYNRTKM--TVGIGGKQAITYYSVITIFK-----------NHTYLRIQLKTGRMHQIRVHLSSIFHPVLGDKIYSKGIKsnfsncsKKMKNFLSKFNRPALHARMLNFIHPKTNKKKNWIIYPPKDMLSLIN----------------------------
>UniRef50_C3XLR7(92-324:353) Pseudouridine synthase n=2 Tax=Helicobacter RepID=C3XLR7_9HELI   E=2e-46 s/c=0.81 id=25% cov=86%
-IPIIYEDSDLLILNKPANLIVHRiDENDTQFTLVDYLKQKgfalsnLGDSYRLGIVHRLDKNTSGAIVIAKNNATHAHLSMQIKSKQMGRYYLCIINQPLKNPQTVEIPIMRHPKQRLKYITTTNNvNAKTAKTAFFMIPTlLDSNFLKTENPKKEIpTLIGAKLFTGRTHQIRVHLNSINRHILGDGFYGYKGNYTG--------RILLHAHFLHLIHPKTQKLLEFHAPIPDDMQNFIK----------------------------
>UniRef50_UPI0001C36F41(76-281:446) hypothetical protein RflaF_04377 n=1 Tax=Ruminococcus flavefaciens FD-1 RepID=UPI0001C36F41  E=3e-46 s/c=0.91 id=35% cov=79%
-LDVpaVYESDGVIVFNKPSGMPVHPSIKHQGDTLGN-KFAAMFPDLTFRAVNRLDRDTSGLCVVAKNALAANA-----LQGRCEKVYYAAVTGEIPETGTIDAPIARERESIIIRCVRED--GQRAVTHYRRIAY-----------NGRYSLAEIHLETGRTHQIRVHFSYIGHPLAGDDLYGGTRCD--------IGRQALHCGQMSFTDPVTGEEVTVRAELPDDIKAIIK----------------------------
>UniRef50_P0AA37(16-219:219) Ribosomal large subunit pseudouridine synthase A n=205 Tax=Proteobacteria RepID=RLUA_ECOLI  E=5e-46 s/c=0.92 id=35% cov=79%
---ILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDY--PQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEY----------AADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFY------ASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKA--PADF---------------------------------
>UniRef50_Q6MM51(1-228:231) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MM51_BDEBA  E=5e-46 s/c=0.82 id=31% cov=85%
MIEILFEDEFFLAAAKPAGMPSQATvdksRQDFFTALKNQLRNERGDAFYLALHHRLDRDTSGVMIFAKTKEANEPLADLFKTHKIQKTYLCLTKRTQKaadaWEVDNHLVEMKDTKLKKTKMVRTQSGGDRAYTKFRKLEVFPEAL-----------LIEAQPLTGRMHQIRVHLADRGMGIYGDDIY-------QAPKNPVAPRLMLHAHALEFTHPFTKEFVRIECAVPADMAQFMKTLTFHS----------------------
>UniRef50_C4V3I7(77-285:294) Pseudouridine synthase n=1 Tax=Selenomonas flueggei ATCC 43531 RepID=C4V3I7_9FIRM  E=5e-46 s/c=0.89 id=35% cov=79%
-LSIIYEDDDLLVLDKPAGQLVHPTTKETHGTIANAvrgYYAACGVHLDFHPCHRLDRNTSGLLLIAKHPEVQYQIAQQ---NTLRREYLALIAGSLtPPEGCIDVPIARALPSIILRCVSTE--GKSACTHYVTVQT-----------DGRYSLLRLQLDTGRTHQIRVHLAHLGHPLLGDDLYGGTRAE--------IARHALHSAHLTLVHPRTKKMLALSALLPADMAR-------------------------------
>UniRef50_C8WV14(85-306:314) Pseudouridine synthase n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WV14_ALIAD  E=6e-46 s/c=0.84 id=28% cov=83%
-VRVLYNDPSLLVVDKPENLLVHRDGSDaPTLDACVQRLLNEEGAGRAYHVHRLDRGTTGCVLYAKHGLMLRAMDAELAAGRVRRTYLAIASGTRIRPGVMSAPIGRD--RHVSGRYRVSRTGKVARTHVEVLDEADQG-------GARWTLVRLRLETGRRHQIRVHLSAMGAPVVGDTLYGGTPHPALAPGQ-----IALHAARLQFCHPYAGEDVEVRAPLPRAWEKL------------------------------
>UniRef50_UPI00016C40E0(9-232:238) pseudouridine synthase n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C40E0  E=7e-46 s/c=0.83 id=32% cov=83%
-LAVLYEDHHLVVVNKPAPLLTQAPPGvpnlEERVRAYIKDKYAKPAGVYLGVPHRLDRPVSGVVCFARNTKAAQRVHSQFEHRSVRKVYWALVEGVVePDAGVWDDYIRKVENEARAARGHEgEPGAKLATLEFRVLERFAA-----------HTRIELHPLTGRMHQLRVQSAWRGHPVIGDSLYGSVRPFGPPAELPRDRVIALHARRLTFEHPFTKQELVIEAPVPAYW---------------------------------
>UniRef50_D1B058(75-310:326) Pseudouridine synthase n=1 Tax=Sulfurospirillum deleyianum DSM 6946 RepID=D1B058_SULD5  E=2e-45 s/c=0.78 id=31% cov=81%
-VPVLYEDEDILVINKPPFLTVHGAPSVKEPTLVDWLQHRGislstiSGEERHGIVHRIDKETSGALVIAKNNEAHVKLASQLEDKSMGRYYLAIIDLPLKENVVVDLPIGRNPNHRLKMAVQRE--GRSAKSAF---------CKCSLSHDGKKELIAAKLFTGRTHQIRVHLSALSRHILGDSLYGFKSHNGT------IPRVMLHAYILYLKHPRSQEMLYIHAPLWDDF---------------------------------
>UniRef50_Q0F1Z5(374-578:579) Pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F1Z5_9PROT  E=2e-45 s/c=0.90 id=29% cov=77%
-IEIVYEDDQLLVVNKPAGLMSTPG-REIEESLFSRLAQRYPQIPELTLVHRLDMDTSGLLLVAKDLRTHKRLQKQFIERSVEKCYEAVLVKRLPaqPDQGRIELPLRVDLDDRPRQMVCYQHGKPATTRWQIIAR-----------ENNRTRIWFYPETGRTHQLRVHASHrdgLNAAIVGDGLYG-----------LPAERLMLHARRLCFTHPVSREPMVFELPAP------------------------------------
>UniRef50_Q1WS68(86-295:304) Pseudouridine synthase n=2 Tax=Lactobacillus salivarius RepID=Q1WS68_LACS1  E=2e-45 s/c=0.88 id=27% cov=80%
-IPIIFENDDLLVVNKPQGIKSHPNQPYETGTLVNYIAgYLDARDEHPYMVHRLDMLTSGAMIVAKNPVVVPILTRLISTHTIKRDYLAITEGIFDQKEGVIDLPIGKDENDKRKRKVDGIGALPARTRYQVIKEFENN-----------SVVYLRLETGRTHQLRVHLSAMGHPIVGDVLYNHVSEE---------KHMMLHGYKQKLTLPFSMRELELKADIPEYFAN-------------------------------
>UniRef50_D2EJM0(86-291:304) Pseudouridine synthase n=1 Tax=Pediococcus acidilactici 7_4 RepID=D2EJM0_PEDAC  E=2e-45 s/c=0.89 id=28% cov=79%
--DVLFENDDLLVVNKPAGIKTHANQPHELGSMINFLQaYFAKKDSNAYNVHRLDQWTSGALLVAKNPVVVPILSRQISQKLIQRTYLCVVEGHLKSRSGTITLPIGLDPHDQRKRQINGPGAQPATTHYQVVREFVER-----------SLLRVQLATGRTHQIRVHLAALGHPIVGDPLYNSLADGAP---------MRLHSWQVKFPLPFSQSWQTVTAPVPNYF---------------------------------
>UniRef50_C8PQT2(9-243:246) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PQT2_9SPIO  E=2e-45 s/c=0.78 id=30% cov=85%
----IYADDDMVAVNKAAGLLVAADRWDAEAPRLDLLIQKELPQiapscNKLYAVHRIDKDTSGILLYALNAEAHRTLNTAFQNREIKKTYRLLIHGRVSEEQFTVDLPLRADGDALHRTVVDKRRGKEAVTHFTVLETFR-----------QFSLLEACPVTGRTHQIRAHLAAAGYPIVCDSLYGSGKPvllselkqrwrGDVYTEQPLIGRLALHAYRLEGVHPRSGQPFAFTAEYAKDFKSTVHQL--------------------------
>UniRef50_Q31HX2(29-228:241) Pseudouridine synthase n=1 Tax=Thiomicrospira crunogena XCL-2 RepID=Q31HX2_THICR  E=3e-45 s/c=0.92 id=30% cov=77%
---VLYEDDDIIVVNKPAGLLSVPGKDLDPEMNLLAQVQKH--VPTALIVHRLDMDTSGIMILAKHKASHRHLSIQFQDRLTEKTYQAICFGKPSTSQGHLNLPMRCDWENRPLQIIDLKQGKAASTHWKLTAQYDNAFE-----------VNLTPVTGRSHQLRLHMKMLGHPILGDNLYADPQSFAAS------KRLLLHAASLKVTHPVTKKTMLFEHP--------------------------------------
>UniRef50_A6DCZ8(69-274:293) Pseudouridine synthase n=1 Tax=Caminibacter mediatlanticus TB-2 RepID=A6DCZ8_9PROT  E=4e-45 s/c=0.89 id=29% cov=75%
-LKPIFETDHFAIFDKPSGVAIHP--KKLANTKSLLDDVRLLYGNDANLVHRLDKETSGLVIASKNKFAESILKQAFQNKEIQKKYLALIKGHLDKEITIKKPIAVNKDENIKVKVIISDEGKESITLVKPIKKI-----------GKNTLVECIPLTGRQHQIRIHLYSIGHPIVGDPLYGVDNEFAdkylkklvdenERIQKTGANRLMLHAYKLEF----------------------------------------------------
>UniRef50_C5VJ38(360-571:571) Pseudouridine synthase n=2 Tax=Prevotella RepID=C5VJ38_9BACT   E=5e-45 s/c=0.86 id=35% cov=79%
-LQILYEDDYLAVVVKPSGLLSIPGKGC-QASIYSILCERWKGKSDAFMVHRLDMATSGLLVVARTSEVHKALQAQFIGRTVKKKYVALLPlsileKQLPAEGRIELPLSPDPDD-RPRQRVDRTNGKPAITEYRLIGKTTYGKEALEAVK-----IALYPLTGRTHQLRVHCAHpdgLGTPIIGDNLYGQRAE-----------RLWLHATHLEFTHPITQERMSFDTPL-------------------------------------
>UniRef50_A5VLP2(78-289:290) Pseudouridine synthase, RluA family n=13 Tax=Lactobacillus RepID=A5VLP2_LACRD  E=5e-45 s/c=0.86 id=29% cov=79%
-LNVVYEDDNWLVVDKPAGVTSIPGPTVQNDTVLNrvkgYLIANNSADLRPHLITRLDRFTGGLLLIAKHHIASSMISQQVQQHQMLKEYTALVEGqVMDEHGEINKPIGRKDGQAAR---VIDENGQRALTEYWVEER-----------GAKWTRVRVRLHTGRTHQIRVHFAAIGHSLIGDHLYGGDTSKY--------DHQLLHASKISFNDPFTLKQMTFTSELPAAF---------------------------------
>UniRef50_C8QW29(88-323:334) Pseudouridine synthase n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8QW29_9DELT  E=5e-45 s/c=0.78 id=28% cov=84%
-FSVVYEDDDLLVVNKPAPLPCHPGGRYFRHTLWRLLQERCGVPKPL-LVNRLDRETSGLVVVAKKRAAARDCARQWQEQQVEKRYLVLVEGEFPLGAQAVAGflapdpasLVRKKSRFFPADQAAPAGAVSCATAFRLLA-----------LQGGISLLEARPLTGRCHQIRATLCSLGFPVVGDKIYGldeelflrflADRLSSDDRRRLRLPRQALHSAGLKMRHPADHRPLEFTCPLPPEMAGLL-----------------------------
>UniRef50_C8W9Q3(10-239:246) Pseudouridine synthase n=2 Tax=Atopobium RepID=C8W9Q3_ATOPD   E=6e-45 s/c=0.80 id=30% cov=85%
-LEFLYQDDYLLAVNKPAGMIVHSDGTNEPsltdlvcEKLCALESSNKIDLSQVQALNRLDKETTGIVLFSLKKETQPQFDQLIASKELSKEYLAVVKGDFGLNKLLIDKAIGKDRHDAQKMRISD-TGKPSQTEVRLIKVASSAQGQIQ------SLLLVNLLTGRKHQIRVHLSSLGFPLVGDVLYGGmSSLQRKTKKKHRPQPLMLHAYRIGFIHPVTGAKIVIKTDIPERF---------------------------------
>UniRef50_Q6FCX9(10-213:214) Pseudouridine synthase n=1 Tax=Acinetobacter sp. ADP1 RepID=Q6FCX9_ACIAD  E=7e-45 s/c=0.90 id=34% cov=79%
----IHRDNDFMVIHKPAGILSVPGKGDALFDSLLVRLVE--IEPKTLLIHRLDRDTSGILVFGLNKMAQSAISRQFQERQTDKIYQALVVGEVYGEGLIDVPVVYDAARPPL-HIADPAHHKPAQTEWQALEQFELN-------GKMVTRMRLTPITGRSHQLRVHMQYIGHPIVGDTLY------ASLADQQLVSRLCLHAEQLSFYHPKTGELVTFHCPVP------------------------------------
>UniRef50_A6VZC6(9-211:212) Pseudouridine synthase n=2 Tax=Marinomonas RepID=A6VZC6_MARMS   E=9e-45 s/c=0.90 id=33% cov=78%
-LEILYEDEWFAVINKPANCLSVPGRG-PDKLDSILYRAECLFGE-AFAIHRLDEATSGLILVAKTHECQKRMYAHFREREVQKEYRALLRGHlLGEKGEVRKPLRCDWPNRPRQIICTDEWSKDSITYWEKMAY-----------ENNTTRVRLVPFTGRSHQLRVHMQSLGHSIIGDEFYDPEFQND--------PRLLLHAYRLEFRHPFTKAWIAFVAACP------------------------------------
>UniRef50_B2IK20(90-337:350) Pseudouridine synthase n=2 Tax=Beijerinckiaceae RepID=B2IK20_BEII9   E=9e-45 s/c=0.73 id=30% cov=86%
---ILFEDRDLMVLNKPFGLAVQGGSGMTHHIDKMLASLPNERGDRPVLVHRLDRDTSGVLLVAKTRRMAAELGEIFRSRQARKIYWAVVEGVPKPAQGRISlylakgegmedkrgPHGRDAEARaglekMRVAKHGEEDARHSVTYYAIVDKVPS----------RLAWLSMKPITGRTHQLRAHAEAIGHPIIGDPKYGLKPKDDPRRNDPnraipeGVERkLHLLARRLILPHPRGG-ILDVTAPLPPHMQKTFDLFGF------------------------
>UniRef50_Q03H72(87-291:296) Pseudouridine synthase n=1 Tax=Pediococcus pentosaceus ATCC 25745 RepID=Q03H72_PEDPA  E=1e-44 s/c=0.89 id=28% cov=79%
---ILYENSDLMVVNKPTGVKTHANQPHELGSMMNFLQaYFKDTENEAYNVHRLDQFTSGALLVAKNPVVVPILNRQISTKVINRTYLCVVSGHLEQSKGTINVPIGFDPDDKRKRQINGLNPLSAITHYQVLAQYENS-----------SLIQVDLETGRTHQIRVHLSYLGHPIIGDPLYNLDNTQQP---------MLLHSWKIRFPLPFNLETIEVTAPIPDYF---------------------------------
>UniRef50_D2LES8(96-319:326) Pseudouridine synthase, RluA family n=1 Tax=Rhodomicrobium vannielii ATCC 17100 RepID=D2LES8_RHOVA  E=1e-44 s/c=0.81 id=29% cov=84%
---IVFENDEMFILNKPFGIAVQGGTKTTRHIDgLLAGMADRFGGERPRLVHRLDRDTTGILAVAKDRQTAARLGRLFQTRSVQKIYWAITRGIPKPTQGKVEaalvkASGPDGDRVRKARPGEQELAQHATTFYSVIDR-----------AANMAWVSLKPVTGRQHQLRAHMDILGTPILGDQKYGDGTEIPIENIERK---LHLHARRLTLKDPKLGE-IDISAPLPSHIAQTFELLGF------------------------
>UniRef50_C7LVL1(16-219:234) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=C7LVL1_DESBD   E=2e-44 s/c=0.89 id=37% cov=77%
-LAVIHEDRDMVVVNKPSGLLSVPGRTPELFDSVLSRVREIHRGAQA--VHRLDLGTSGVLVVATRRKAETILRQQFQDRLTRKLYLARVQGVMSEDSGQVDLPLICDWPNRPMQMVCHDTGKPALTDYQVLES-----------DGESTLVLLRPHTGRSHQLRVHMASLGHPILGDNLYGEQRPGE---------RLLLHASQLGLYHPYSGEWTTFHAP--------------------------------------
>UniRef50_A7K2Y9(14-245:250) Pseudouridine synthase n=4 Tax=Vibrio RepID=A7K2Y9_VIBSE   E=2e-44 s/c=0.78 id=26% cov=90%
-VDIVFEDDDILAVNKPSGLLSVPGRLAEH--YDSMWSRLKEVHPEIQVVHRLDMSTSGLMLLAKNKPSERALKKQFQYRLTHKVYYARVWGHVEPQEGNIDLPLICDWPNRPRQKVCFDDGKPSQTLFQVVKR------EVHSDGTHTTVVRLLPITGRSHQLRVHLMAIGHAIVGDEFYATEEAYQFSE------RLELHAAELSFYHPATDQLSSIFVPC--DFYPEAEAMIFNYFSPERTLPDYK-----------
>UniRef50_Q1CZL9(354-558:559) Pseudouridine synthase n=5 Tax=Proteobacteria RepID=Q1CZL9_MYXXD   E=2e-44 s/c=0.88 id=35% cov=78%
-LDIVFEDEWLVVVEKPEGLLSVPAKDVSVEDSVLARLRaRAPEAAGTMLAHRLDLDTSGLLVAAKDARTYAALQRQFAGREVHKRYAAWVEGNVQGERGTIDFPMRVDLDDRPRQIHDPVHGKPAVTEWHVLER-----------SHGRTKVALFPLTGRTHQLRVHAAHplgLGAPIVGDRLYGHPG-----------PRLHLHAEALSFQHPVTGQRLTLERPAP------------------------------------
>UniRef50_B9XBT8(25-256:260) Pseudouridine synthase n=1 Tax=bacterium Ellin514 RepID=B9XBT8_9BACT  E=2e-44 s/c=0.78 id=27% cov=77%
LFDVVHEDAELLVINKPAGLVCHPTKGDEYSSLISRVRLHLGPESHPHLVNRLDRETSGIVIVAKDDTTARGLRRIWEGREVQKEYLAIVHGHVrEEQGTIQAALGKDTSSIIAIKDTVVEGGAASQTDFTVKKRF-------SREEGDFTLLRVLPHTGRKHQIRIHLAHIDHPIVGDKMYGGdedlymalvqDRLTEEQWKKLILPHHALHARAVR-----------------------------------------------------
>UniRef50_B9ZR86(99-321:328) Pseudouridine synthase, RluA family n=1 Tax=Thioalkalivibrio sp. K90mix RepID=B9ZR86_9GAMM  E=2e-44 s/c=0.81 id=29% cov=83%
---ILHEDDQVLVLDKPSGLAVHGGSGLAFGIIEAMRQLRPGSELELG--HRLDRETSGCLLLAKSRSGLQDFHAALREGRVEKRYLALQVGAFPSDQpiVCDEPIASSRGPDGKRRMRagedaDPESARSAISQFVPLERY-----------GSFQLAEVRIGTGRTHQIRVHGQAIGHPVGGDHDYGLPDANRVLRGA-GLKRLFLHAQALQYEDSAS-ESHVYSAPLPDELQSILDAL--------------------------
>UniRef50_C5NUK8(80-291:293) Pseudouridine synthase n=1 Tax=Gemella haemolysans ATCC 10379 RepID=C5NUK8_9BACL  E=4e-44 s/c=0.85 id=28% cov=78%
-INIIYEDAYFLIVNKEINLPSIPSRNLEDESLleiVNYYFKKKNINTIPHIVTRLDKNTSGLVLIAK----HRHVHALFSNMEIDKFYTALVSGKVKDNEIIEAPIRRVTSSIIEREV--GEGGEFAKTEYWLDDYI---------VDKDISVVKLKLYTGRTHQIRVHMKYKDYPLLGDELYGGDVSN--------ISRQALHCTNLKFIHPITDEVVNVRADLPED----------------------------------
>UniRef50_Q0C3G8(95-335:349) Pseudouridine synthase n=2 Tax=Hyphomonadaceae RepID=Q0C3G8_HYPNA   E=5e-44 s/c=0.75 id=28% cov=84%
---IIHEDDDMLAINKPAGLAVQGGSGQGRH-VDGLIAGMDVDGHRPVLVHRLDKDTSGVLLLAKHPAAAARLTELFRSREMDKVYWAVTVGVPSPQAGQIRCWMvkgvpdinepsgyrpvdpyatKRRDGDRERMIRSAqgvEGARHSITDYVVVST----------AGPKAAWVAMRPETGRMHQLRFHMLEMNTSILGDYKYKSRREVPQG----LAEGLHLHARALIIPR-EHGKPIKIVAPLPPHMKETFETLGF------------------------
>UniRef50_C4L584(79-287:287) Pseudouridine synthase n=1 Tax=Exiguobacterium sp. AT1b RepID=C4L584_EXISA  E=5e-44 s/c=0.86 id=28% cov=80%
-IRILYEDDTLLAVDKPAGIATIPSRLHPTDTLANAvlgYYQRIGLSSAIHVINRLDRDTSGVVLFAKYGFIHHRFSELQKANGLMRTYKALVEEEVT-PQTIDAPIGRAENSIMERVVTTE--GQRAITHI-----------LACQPFGSGSLLTIRLETGRTHQIRVHLRHIGHSLIGDSMYGGTA---------RMPRHALHSASARFIHPMTGDTIQIEAPIPEDFRTV------------------------------
>UniRef50_Q5GT77(88-385:389) Pseudouridine synthase n=8 Tax=Wolbachia RepID=Q5GT77_WOLTR   E=5e-44 s/c=0.60 id=32% cov=87%
--NILYEDEYILAINKPAGVIVQGGIKVKISISDLLDQVRE--GETFKIVHRLDRDTSGAIIFARNANVARYLMEEFKGRRVKKTYLALTSGIPsKNRGVIDYPLVKKYVSGQEKVVIDKNSPQDATTRFSIIAKFKLNKPLvqrpiiqvadtqlyehcnlslsrvchlsslsscyssallchlsapilvssktdhkqahyttfsikkldssimCRNDTRSVAYLKLQPITGRTHQLRTHLAYINCPILGDGKYGGKKAFVDGIASK----IHLHSYSLSLKLP-NNKKITITAPLPEHIKKSIEAL--------------------------
>UniRef50_A9CFZ5(18-221:222) Pseudouridine synthase n=3 Tax=Rhizobiales RepID=A9CFZ5_AGRT5   E=6e-44 s/c=0.88 id=32% cov=79%
-LTIVHRDDDLLVLDKPSGLLSVPG-RDPALSDSLMTRVQKQFPKALMI-NRLDKDTSGIVLMSLNRKAHAAIAAQFEKRETRKSYVAIVWGTVAGEEGEVDLPLAIDPDNKPRHRVDHENGKPAQSLWRVLERLPLP----------ATRLALTPLTGRTHQLRVHMKALGHPILGDEFY------AEGEALTAAPRLMLHAQEVGFRHP-DGRDVTYTVPCP------------------------------------
>UniRef50_A8HZL1(87-307:319) Pseudouridine synthase n=12 Tax=Alphaproteobacteria RepID=A8HZL1_AZOC5  E=6e-44 s/c=0.81 id=31% cov=84%
----LHRDGMVLVLDKPAGLPVHPGPKGGETLHDHLNGLRFGLPRAPELAHRLDKDTSGCLVLGRHGKALALLNRLFAEGQADKTYVAVTRGAPaEETGRIDQPLAKRSPHRGWWMQAVPkgtPGGLEAVTDWRVLARTE-----------GLAVMALSPVTGRTHQLRAHLSHIGFPILGDSIYGGASRLPGGPM------LHLHSRRIVLPVAKNGPAIDARAPLPPHMVETLTALGLES----------------------
>UniRef50_Q38Y05(83-296:296) Pseudouridine synthase, 23S-rRNA-specific n=1 Tax=Lactobacillus sakei subsp. sakei 23K RepID=Q38Y05_LACSS  E=8e-44 s/c=0.84 id=30% cov=81%
-FSVLFESDDLLIVNKPAGIKTHPNRPGENGTLMNQvAFYLAQQGKKAYMVHRIDEATSGTLLIGKTPIVIGILNRQLSQKKMARQYIAIVDDPkheLAEHATINSPIGVDPENDRQR-CVDYINGLSAITHYRVLSR-----------KGATAVLAVDLETGRTHQIRVHLASIGHPILGDPLYNPTDTT---------PRLLLHGQTLRYTEPYTDQPRTVTAPVPDAFEPYLS----------------------------
>UniRef50_Q8DCG0(15-246:250) Ribosomal large subunit pseudouridine synthase A n=82 Tax=Proteobacteria RepID=RLUA_VIBVU  E=9e-44 s/c=0.77 id=28% cov=76%
--EIIFEDDHILAVNKPSGLLSVPGRL-PEHHDSMWSRLQEQY-PEIQVVHRLDMSTSGLMVFAKNKRAEAALKKQFQYRLTHKVYYARVWGHVEADSGMIDLPLICDWPNRPMQKVCHEHGKPSQTAFQVAKR------EVHANGAQTTIMRLLPVTGRSHQLRVHMQALGHPIVGDEFYAQGDAFTFSE------RLELHAAELSFYHPKS-----------------------------------------------
>UniRef50_B2UKZ0(16-255:258) Pseudouridine synthase n=2 Tax=Verrucomicrobiaceae RepID=B2UKZ0_AKKM8  E=1e-43 s/c=0.75 id=29% cov=86%
-FEVAAESGDWIVVDKGAPLIVHPSNGKKEPCLLegveALLSYEIANGAALSLVNRLDRETSGLTLVAKHKRAARELGRAMQRRLIHKEYLAIVQEWPEWTETactaPILRQGEVAESRIWVKQAVHPAGKACTTVFRKERTWNTRR-------GPLALVRCIPETGRMHQIRVHLAHLGHPILGDKIYGPSEHcyleyiqhgwSRELEERLVLPRHALHACRLEF--PFDEETFTAEAPLPEDMRLLLE----------------------------
>UniRef50_B9L6Z5(69-273:294) Pseudouridine synthase n=1 Tax=Nautilia profundicola AmH RepID=B9L6Z5_NAUPA  E=1e-43 s/c=0.87 id=29% cov=75%
-LKPIFETTHFAVFDKPSGVAIHP--KKLANTKSLLDDVRSLWGNDANLVHRLDKETSGLVMASKNKFSESVLKKAFQDKEIQKKYLALVKGHLEKDLTIKKPIAVNKDENIKVKVMIHPEGKESVTIIKPIKKI-----------GENTLVECIPLTGRQHQIRVHLFSIGHPIVGDPLYGVDNEfadrylnklidEKERIEKTGAKRLMLHAYYLEF----------------------------------------------------
>UniRef50_Q1QR55(14-291:292) Pseudouridine synthase n=4 Tax=Bradyrhizobiaceae RepID=Q1QR55_NITHX   E=3e-43 s/c=0.64 id=29% cov=91%
---VLHRDGLMLVIDKPAGIPVHRGPKGGANLEASFEALRFGLPRPPVLAHRLDRDTSGCLVLGRHRKATASLGLLFKHGKISKTYWAVVEGGPTEDEGTIDIPLGRLNHERGWWQKPDPNGLPSVTRWKVLGRgiftaasdrfspspcgvetsearpegagargnsdgiaPDHPPPRAREEGIQLTWLALEPVTGRTHQLRVHCAAMRWPIAGDNIYGTQAslrrlRNEQYIPQFGEPSLHLHAREIAIPLSKNKPPIVVTASAPVHLHARLKACGWNG----------------------
>UniRef50_A6DHD2(93-326:328) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DHD2_9BACT  E=5e-43 s/c=0.75 id=26% cov=83%
-FKVVYEDDDILMVEKTGDLPVHPAGSFFKNTLWYMLVKQFG---NVHIMNRLDRETSGLVLIARHHKAASVLGKQFERRQVGKEYDVLVEGLVSWDQYDALGYMgpavsskiRKKFSFTEAEDWQDYGKHSARTEFSVLRR-----------SHELSHLHCRLHTGRTHQIRATLLSLGFPLVGDKIYGldeqfflsfiDGALTEQDYQKMRLRRQALHCSLMSFTHPMSGEDVVFESSLPKELAELI-----------------------------
>UniRef50_Q0VQA6(26-228:229) Pseudouridine synthase n=7 Tax=Gammaproteobacteria RepID=Q0VQA6_ALCBS  E=2e-42 s/c=0.86 id=30% cov=78%
----IYRDEHLLLINKPAYLLSVPGRA-PENKDCAIRRLQQRY-PDIRLVHRLDLDTSGIMVFGLTAFAQSKLSRLFQLRTVKKRYQAIVHGLVEKNAGSIDLPLIADWPKRPLQKVCHETGKNALTHYRVLER---------DIPGNRTRLALSPVTGRSHQLRIHCRELGHPIIGCDMY------APAEIEALSPRLLLHAEWLAFNHPLTGLWQEFTSPCP------------------------------------
>UniRef50_C6E472(78-299:302) Pseudouridine synthase n=4 Tax=Geobacter RepID=C6E472_GEOSM   E=2e-42 s/c=0.79 id=30% cov=83%
-LDILFEDSWIISLNKAPGLSVHRTEDPDEVNLVDLaetLLQKRDGVGRLRPVNRLDKGTSGAIILAKSAVAAGMFGKMVQEEGLGKLYLALVEGKLQKQGVIDAPL----------------DGKESQTSYLRL-----------FHGGGVSLLAVYPITGRMHQIRQHFKMIGHPILGDKRYGG-------RALTGFTGHALHSFKTTLVHPATGEEVNIPAPLPEQLMRLVSRYSGvseKALLDTLDQLPASGP---------
>UniRef50_Q037L4(73-285:293) Ribosomal large subunit pseudouridine synthase D n=8 Tax=Lactobacillus RepID=Q037L4_LACC3  E=2e-42 s/c=0.82 id=27% cov=81%
-LEVIYEDANWLIVSKPAGLTSVPGPHTPNSSLLNriagYLVEQKIDAPQPAIMTRLDRDTVGLVLAAKHPYAQGRFDQAHQ-RTLTKHYLAVVSGKLPSPKGEIDAPLKLAADGIHRIVAAD--GQTALTKYRVLKEKTN------------TLVDVQLLTGRTHQIRVHFASLGHPLIGDHLYGQPDA--------RIPYQALQATRLKFTDPFSEKRITAELPVPALFNQLLTE---------------------------
>UniRef50_O66114(7-217:219) Uncharacterized RNA pseudouridine synthase ZMO0505 n=10 Tax=Sphingomonadales RepID=Y505_ZYMMO  E=3e-42 s/c=0.82 id=32% cov=79%
---VLFIDAEAMIIDKPAGLPVTSVRDGSLSLENYLASLCFGFKRWPSIVHRLDRDTSGCLLLARNPKMHRRLSEAFSQGQVKKCYWAILEGVPeKNEGIIDLPLLKISSPKSGWRIVADDKGKRAVTHWEILA-----------KNKGRSLVAFRPETGRTHQLRVHAAtGLGLPIVGDPFYGSHKDE-------NISRMMLHAHSLEIAR-LEKKPITAEAPLPKAF---------------------------------
>UniRef50_C0CMK8(82-310:310) Putative uncharacterized protein n=1 Tax=Blautia hydrogenotrophica DSM 10507 RepID=C0CMK8_9FIRM  E=3e-42 s/c=0.76 id=29% cov=79%
---VLYEDESLVVVEKRSGQVCHPSGMHYRDSLANQLVWHFQNRQEntsVRIIGRLDKDTSGIVVAAKHKIAAQKLSWQRDRGIFGKEYLALVHGEFsDFDGFLREPIARVQGHPLKMKVC--AQGKPAKTQYHVIAQ-----------NRGYALVSCRLYTGRTHQIRVHMQSIGHPLVNDVIYGLGEQDDFAKTLENEQKIAgdrhkklgLHAAKVWMRHPLSGEELILES---------------------------------------
>UniRef50_C5BU65(4-207:208) Pseudouridine synthase for 23S rRNA and tRNAphe n=1 Tax=Teredinibacter turnerae T7901 RepID=C5BU65_TERTT  E=7e-42 s/c=0.85 id=33% cov=79%
-LAIIYQDDHIIAINKPAGLLTVPGLATPDNAFDQLVHQH----PNSRVVHRLDMATSGLVIFPQSHESLVRFGRLFEQRKMTKTYTATVAGIVAEDRGEITLPLICDWPNRPKQKVDLEQGKHAHTQYKVLER---------RLDLQTTRIELTPITGRSHQLRVHMQQLGHPILGDAFY------APDAIQQASDRLLLHATTLEFVHPFTQCPTSIHCEPD------------------------------------
>UniRef50_A3VN52(97-316:324) Ribosomal large subunit pseudouridine synthase C n=1 Tax=Parvularcula bermudensis HTCC2503 RepID=A3VN52_9PROT  E=2e-41 s/c=0.78 id=29% cov=83%
---VIYEDDDILALNKPAGLAVQGGAKTLIHIDGMLDVFGEG-EARPRLVHRLDRDTGGVLLLAKSRAVAATLSLAFQQHRIGKTYWAITKGVPHPLFGRIDMRIEKAGEPGREKMRGTEQGQSALTDYQTVET----------AGQKAAFLALRPHTGRTHQIRVHLSAIGTPIVGDRKYGGAGAVLEGLP----NQMHLFCRQMHV--PRRGRpPLVVTADLTGGMATSWSIFGF------------------------
>UniRef50_B7I1Q3(29-228:229) Dual specificity pseudouridine synthase n=17 Tax=Acinetobacter RepID=B7I1Q3_ACIB5  E=5e-41 s/c=0.85 id=31% cov=77%
------EDDDLIVVDKPAGLLSVMGRLPEHHDSAYLRVLEKFPLAKVT--HRLDMATSGLLMFAKHRDAEVAVSKMFQARTVKKHYIALVQGQVKQEGRVEVPLITDWEN-RPRQIVHFELGKHAKTLFQPLVYDE---------TTDQSRVLLEPVTGRSHQLRVHMMHIGHPIMGDKLY------HPEPKRFHLNRMALHAAYLAFQHPLKGTDVVIESQVP------------------------------------
>UniRef50_C9LG01(8-232:245) Ribosomal large subunit pseudouridine synthase family protein n=4 Tax=Bacteroidetes RepID=C9LG01_9BACT  E=6e-41 s/c=0.76 id=31% cov=78%
--EILYEDNHIIIVNKQAGEIIQ---GDKTGDRTVADEIKAYLKEKynkpgavfLGIPHRLDRPVSGVSIFARTSKALARLNEMFRKGEIEKTYQAIVIHEPQIaSGTLVHWLTRNEKQNKAYAHKaPQKNAKKAILDYKVEAKSD-----------RYWLINVQLQTGRHHQIRCQLAAIGCPIKGDLKYGAPRSNADGS-------ICLHARSIRFEHPVSHKIIFAEAPYP------------------------------------
>UniRef50_B1C9B9(81-306:307) Pseudouridine synthase n=1 Tax=Anaerofustis stercorihominis DSM 17244 RepID=B1C9B9_9FIRM  E=6e-41 s/c=0.75 id=24% cov=85%
-LNIIYEDKNIILIDKPSGILSQADGSSKEDIVSNLISYLNSKST--GIVTRLDLNTSGIVLAGKNRRALMLLNEMSKNKLIDKRYLTLVRGDFDREGKVTHYGIKDNKENKLILGNKKVDG-----SFEVSAEFIIKKRYKY-----HTLLEVRLITGKTHQIRSQLDKMGFPVVGDRKYNKSKQC-GNKDDFKINRQFLHCYKLTLKYSEKYKEIvtedkTFYSDLPKDLKNVLKELG-------------------------
>UniRef50_P59831(14-220:222) Ribosomal large subunit pseudouridine synthase A n=20 Tax=Proteobacteria RepID=RLUA_HAEDU  E=8e-41 s/c=0.82 id=33% cov=77%
-LEEVYRDNHIVVINKPSGLLSVPGNRPEYYDSVMTRVQQRYGFAE--PAHRLDMATSGIILLALSKVAEKELKRQFRDREPKKHYIALLWGKLgdrvGQTGEINFPLICDWEN-RPRQKICYERGKKATTHYEVLEHL----------ANNTTRVKFTPITGRSHQLRVHSLALGHPIIGDKFYANPL------AKSLAPRLCLHAESLTIAHPISAELMTF-----------------------------------------
>UniRef50_B3DY53(11-258:268) Pseudouridine synthase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DY53_METI4  E=3e-40 s/c=0.67 id=26% cov=89%
---IVEECQDYLIVDKPPFLLSHPTRKKKGPSILEWLQ-NLHPGISFKLIHRLDRETSGLLVVAKNSAAAAYFGRQMEKRLIQKGYLAISWGELKADYLKIEAPLGYLGGAKGNEIVIRQGIVPHGTQ-------SVTEIYPLGHGGGYSLLWVRPLTGKLHQIRVHLSTIRHPVVGDKLYGPNPSfflefakrgwTEEMEKVLLLPRHALHAAYLSFF--WKGDKKQFYSPLPEDLKKFlglvqnLSKLQLNNPILAND----------------
>UniRef50_B0PEI9(101-304:338) Pseudouridine synthase n=5 Tax=Bacteria RepID=B0PEI9_9FIRM   E=3e-40 s/c=0.82 id=30% cov=74%
-IDIIYEDENILLVNKPAGLVVHEDEHQSSDTLINRIQHHlyncgvynpaEENSFAPALCNRIDRNTAGIVIAAKNAAALRILNEKIKARELQKLYLCIVHGTMPKESDTLKAFLRKDARTNTVAVYDHpiPDGRTILTHYRVVAQKD-----------RLSLLEIDLLTGRTHQIRAHLAHIGHPLLGDAKYGRNRDNH----KTGLKHQALCAYKLTF----------------------------------------------------
>UniRef50_C5DEF5(184-361:610) KLTH0C08756p n=2 Tax=Saccharomycetaceae RepID=C5DEF5_LACTC   E=3e-40 s/c=0.94 id=29% cov=65%
-IKIVFEDQDLFVIDKPSGIPVHPTGRYRFNTITKI--LQKQINGSVHPCNRLDRLTSGLMFLAKTPRGADHMANQLKAREVKKEYIARVVGEFPAERISVEKPLKCVEPRLalnGVCNSEEEGAKEAKTVFTRVS-----------FDGETSLVKCQPHTGRTHQIRVHLQYLGHPIANDPLY-------------------------------------------------------------------------------
>UniRef50_C0FY60(59-287:294) Pseudouridine synthase n=1 Tax=Roseburia inulinivorans DSM 16841 RepID=C0FY60_9FIRM  E=4e-40 s/c=0.73 id=31% cov=78%
-LQVVYEDDDVIIINKPSGMLSQKAvpEDISANEYILSYLIRKGALSEeqfktfkPSICNRLDRNTSGLLIAGKTLKGLQTMAEALKKRTVQKYYRCIVKGELREKTHLKGYLSKDEQNNKVKVVSHIRPEEKA--DYLPIETEYRPVAV----SNGYTELEVHLITGRSHQIRAHLASIGHPIVGDGKYGDLRTNERFRKEVHVRSQLLHAYRIVL----------------------------------------------------
>UniRef50_Q1PXB6(75-272:274) Pseudouridine synthase n=1 Tax=Candidatus Kuenenia stuttgartiensis RepID=Q1PXB6_9BACT  E=4e-40 s/c=0.84 id=33% cov=75%
--DILFNDDCYVIVSKPPGIVT-----NGQNSIE-RDLRTQFNRDRIQAVHRLDKDTSGALIFAKNENAFEEMKKVFKKHDIQKIYRVIVTGKICEPAFTINSPV---------------GGQTAVTHITLLK-----------KGKNTSYLEVATETGRRHQIRIHLASIGHPVIGETEY--ARKEIENILHREAKRQMLHAHRISFVHPYTKKEISVTAPISHDFIQCL-----------------------------
>UniRef50_A8RUB2(119-353:366) Pseudouridine synthase n=3 Tax=Clostridiales RepID=A8RUB2_9CLOT   E=4e-40 s/c=0.71 id=29% cov=75%
-LDIVYEDQHILVVNKPSGMLSQKAKDSDMSLNEYILNYLIDSGKlpisqlrtfKPSICNRLDRNTSGLVVAGKSLAGLQVMNEVFKDRSIHKYYQCLVAGEIKEKQLIAGFLKKDEsTNTVSIFPLEVEDSVPIMTEYLPLS-----------GNKTFTLLQVTLITGRSHQIRAHLASIGHPIVGDYKYGSRSLNDAVKKKYAVRSQLLHSWRL------------------------------------------------------
>UniRef50_D2QLU1(6-232:248) Pseudouridine synthase n=53 Tax=Bacteroidetes RepID=D2QLU1_9SPHI   E=6e-40 s/c=0.73 id=33% cov=81%
-FQVVYEDNHLLIVNKDPGILVQ---GDRTGDITLLDVLKDYIKEKynkpgevfLGLVHRLDRPVSGLVVFARTSKALERMNEIFRKRQVQKTYWAVVRRKPPKdsDKLVNWLIKDEQKNQVTVYDYEVPKSQKAELSYRVLGKI-----------NEHYLLEVNPITGRPHQIRSQLAHMGCPIRGDIKYGYDRAVAD-------KKIYLHARRLYFIHPIKQagaedRPIICKAGLPNDpfWEEFLE----------------------------
>UniRef50_C6XLD8(41-264:272) Pseudouridine synthase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XLD8_HIRBI  E=6e-40 s/c=0.74 id=33% cov=82%
------EDDSILAFNKPSGLACQTRSPADRTFDALLQVYVKRNGKRPRMLHRLDMLTSGVIIAARTKPATSFFQQTFERREAYKSYLAIVRGPafEKSEGVIDAHLQRYQKEPnlalMRPCDVDGEGAQDARTRYLVLSS-----------QNDYHFLLLTPETGRTHQLRVHLEHFGRPILADPYYGTDALEGSYQPA----RLMLHAYRLLTPHPDGGE-IDIIADVPDDMKECLTAL--------------------------
>UniRef50_Q6AIJ2(4-206:211) Probable ribosomal large subunit pseudouridine synthase A n=1 Tax=Desulfotalea psychrophila RepID=Q6AIJ2_DESPS  E=8e-40 s/c=0.82 id=35% cov=77%
-LKIIYRDDHLVVVIKPGGLLSVPGRG-PENSDCVSSRLQAKIPEMITqpAVHRLDMYTSGLMVYAVSKEIHRALSIQFQEQQVDKKYTALLEGCLQEVSGEIRLPFRVDLDNRPIQILDYQHGKMGITLWRKMD-----------EKNGITRVEFTPMTGRTHQLRVHAAHakgLGIPIIGDSFYGSGRDGDE---------MMLHAHQLSFTHPIIGEKLYFK----------------------------------------
>UniRef50_Q5FSR8(46-261:265) Pseudouridine synthase n=1 Tax=Gluconobacter oxydans RepID=Q5FSR8_GLUOX  E=1e-39 s/c=0.76 id=28% cov=83%
-IPVLLETPRFLILYKPAGLAVHPGPSTQDSVETRLLPHPRGG---PWLAHRLDADTSGCLLVARRKTALIEAQKAFQERQAHKLYWAVVVGDLPQDSGEIDAPLLRQSDASGWRMVVDAKGDEARTRWRVLGRSK-----------GLCWVELELLTGRTHQARIHCAELGTPILGDPVYGMPAPDGSA-----LPGLHLLARSLELSLPSD--TLSAQAPPPEFMAASLRAMGFES----------------------
>UniRef50_B2GFH2(102-313:326) Putative pseudouridine synthase n=1 Tax=Kocuria rhizophila DC2201 RepID=B2GFH2_KOCRD  E=2e-39 s/c=0.77 id=29% cov=82%
-LDVLHEDEWIMAVDKPHGLCSTPKGENVRRSVVVAARCQFDNDE-ISALHRLDRSTGGVLLLCKRAEDRSAFHRLFQERTVRKTYWAVAGVNERVGEQTVRVESRIRKIQGVVQAFEEPGEVNAVTDVRRVETFT-------DADGTWGLYEIAPLTGRTHQIRVHMTSLGLPLRGDKLYPQPRQD--FDVEDPENPLQLIARSIEFVHPVTGRAVRIDSRL-------------------------------------
>UniRef50_Q1IZY6(15-247:251) Pseudouridine synthase n=3 Tax=Deinococcus RepID=Q1IZY6_DEIGD   E=4e-39 s/c=0.70 id=29% cov=82%
---VLVEHPDFYVVHKPALWLTHPVRARVDVPDVLSYMRAETGEPDLAPPHRLDRETSGTQLLSRDPDAARRFFTLFKTHLVGKTYLAVVHGSPDWERYTLDAPLGDLGlggaNRVIIRQAVVPDGRPAVTDFRVVEQR-----------GGFTLIEAYPRSGRLHQIRAHLSHLGLPLVGDKIYGPDPQAFLDFMHHGqtlelterllLPRQALHAARIAF--PWAGAQFAAEAPLAPDLR--------------------------------
>UniRef50_A8S647(86-312:316) Pseudouridine synthase n=3 Tax=Ruminococcaceae RepID=A8S647_9FIRM   E=8e-39 s/c=0.71 id=29% cov=82%
---VVYDCPQILIVNKPAGVAVDGPEDDTLLNRALLYLnkqgeYKENDLYTPALCHRLDTGTSGLVIIAKTPEAEELFLSAIKNREVQKTYLCVTFGRPmPPDATLGGYLLKDADRGIVKIVEDKqPGAKEVETRYETIAV-----------SGRLALLKVQLITGRTHQIRAHMASIGCPILGDSKYGNNSANR----ELKLKYQALCAWELtmpRFTQPdfafLSGK--TFHAPKPWYYQQVLD----------------------------
>UniRef50_A0LXI9(80-283:289) Pseudouridine synthase n=1 Tax=Gramella forsetii KT0803 RepID=A0LXI9_GRAFK  E=1e-38 s/c=0.79 id=33% cov=77%
-FEVLFEDEHIAVVHKPPGF---PTSGNYFKTIENALPHNLSSSseidtlPYPLPAHRLDNPTSGILLCAKTNSSLIKLQEAFAQKQIQKTYYAIVSGEIKEKIEIDSPIDQ-----------------------KISKTILIPIEFYQIENKNYTLVELNPLTGRTHQLRIHLSENNTPIIGDNLYGKEETNLLKNKS-----IYLFAGKISFDHPLSKKLMTFQLQLPKKFRNL------------------------------
>UniRef50_C7NCB1(72-378:380) Pseudouridine synthase n=3 Tax=Fusobacteriaceae RepID=C7NCB1_LEPBD   E=1e-38 s/c=0.53 id=27% cov=86%
-LDIIFEDEDILVVNKEPFLLTHPTQKKADFTLangiVNHFFEKYGEVRVPRFYNRLDMNTSGLIIIAKNSFAQAFLQN---FSIFEKKYLAIVNGIIDDKGIARINEELAKDGEKHKIQdlekenlksevekinfgkvkkyeeiekiesnlnVENEDSKIAEnTNFdnkdnnlnlanksnfenenlkenktkiiierrifrdgenleRIIDTRgqyakTAIKVLKVYPEKNVTLVECELFTGRTHQIRVHLKSIGHTIVGDELYGNG-----LNKELGINRQFLHAYKVKFIHPALKKEIELEIPMFKDMKEFLE----------------------------
>UniRef50_A9B0U7(66-289:312) Pseudouridine synthase n=1 Tax=Herpetosiphon aurantiacus ATCC 23779 RepID=A9B0U7_HERA2  E=1e-38 s/c=0.72 id=26% cov=81%
--DILFEDEWILVLNKPAAWYSVATPWDTFGHLEGALQRffleRDGEAVPFHLVHRLDHGTSGALIVSKNPSLNSRFQRMFNEGRVQKTYLALCSGLPDWTKLEVVTGHSRGEFGLWSVYpaamidqlygPKDRRVRRAHTSFTVQAVGNAAALLAA-----------RLHTGRTHQIRLHAKHIGHPLVGDQRYGGVTQFG----NLSIPDQLLHAAWLQFPHPRYGSMLELIAPVPSLW---------------------------------
>UniRef50_C6LAK4(56-266:272) Ribosomal large subunit pseudouridine synthase D/dephospho-CoA kinase n=1 Tax=Bryantella formatexigens DSM 14469 RepID=C6LAK4_9FIRM  E=2e-38 s/c=0.76 id=29% cov=79%
--DIIYEDKQLLVCRKPAGLAVQNASFGRMDLESMVRNYlmekSGKPNPYLGVVHRLDQPVQGLLVFAKTPAAAAALSAQVQDGRMTKEYLAVVCGKLPeKEGELVHFLKKEPAGNCSRAVGEKtPGAKRAELSYRVLAEAD-----------GRALVRIKLKTGRHHQIRVQMVACGAPLYGDAKYNPGAQRGE--------RLALCADRLSFVHPAGGKRVEFTCR-PDNF---------------------------------
>UniRef50_Q49WD7(75-270:284) Pseudouridine synthase n=5 Tax=Staphylococcaceae RepID=Q49WD7_STAS1   E=2e-38 s/c=0.82 id=28% cov=75%
-LNILFEDDYLIVVSKPPYQNCAPSRDHLHYSIveqVLGYLNEKQPGINPHIVTRLDRNTSGIVILAKHGFIHHLMSNL----NIDKKYLCICYGKTEKEGVIDAPIARHPESIIQR--RVDAAGKTAQTRFKRVEYKE-----------GFSMCEVTLLTGRTHQIRVHFQHIGHSIVGDALYGG--------KHESYHHQLLRCTQVAFIHPIKNQNIVI-----------------------------------------
>UniRef50_C3PKB5(127-344:353) Pseudouridine synthase n=7 Tax=Corynebacterium RepID=C3PKB5_CORA7   E=2e-38 s/c=0.74 id=24% cov=84%
-IPILFEDEHLLVVDKPPFMATMPRARHITETATV-RLRRKTGNNELSPAHRLDRLTSGILVFTKDRSVRGAYQTLFAERRVTKTYEAIA--PLADVSPGTVWRSRMEKTPGELQGRIVEGEVNAITEVAAVEPIdKAPYESIHGSLPELAKYTLKPQTGKTHQLRLHMLQAGVPIIGDPIYPVIFPAEAEDMRIP---MHLTATHISFVDPLTARPREFFSQLP------------------------------------
>UniRef50_C9L5B3(30-234:244) Pseudouridine synthase, RluA family n=1 Tax=Blautia hansenii DSM 20583 RepID=C9L5B3_RUMHA  E=2e-38 s/c=0.79 id=28% cov=78%
---VLYEDKYILVCQKPAGFPVQSKRLGTLDMECALrnYLAKKGQEPYVAVIHRLDQPVQGVLVFAKDKESAAKLSKQMQQGKFEKTYLAYTQGHtDKKQETLIDELEKDGRTNTSKVVaKKTANSKRAELSYKVLKETEEG-----------SLLEVSLKTGRHHQIRVQLAHAGLPIFGDAKYNVKCTKEDANHGVS-----LCAYKLSFLHPAKGKKMEFQ----------------------------------------
>UniRef50_Q11Q54(20-242:242) Pseudouridine synthase n=7 Tax=Bacteria RepID=Q11Q54_CYTH3   E=4e-38 s/c=0.72 id=30% cov=83%
-FTVVFEDNHLIAVNKKNGVLVQGdDTGDKPLSELVKEYLKKKYNKPgnvfAGVIHRIDRPVSGLVLLAKTSKALERMNKQFADKKIQKAYLMVSGSKPnPASAKLVHWLTKDAKRNIAK----------AHTSEVKESKYCELSYSLLTSSDRYFLIEVKPVTGRSHQIRCQMASIGCVIKGDLKYGAPRSNPDG-------GICLHSHKLSFQHPVTGDNMQLKADPPkgEPWNALLKK---------------------------
>UniRef50_UPI0001BC3376(6-215:222) putative 23S rRNA pseudouridine synthase n=1 Tax=Butyrivibrio crossotus DSM 2876 RepID=UPI0001BC3376  E=6e-38 s/c=0.76 id=26% cov=79%
---IVYEDDNIIVCNKPVGMPSQSDRTFEQDLVSYVLTHRTEQNEPAYaaIINRLDKPVGGLVLFAKNKKAAAGLSAVSGEHGIEKNYYALVKGSPCDKGEFTDYLLKDGKNNISTVTDKDTKGsKKAVLLYEKLGEKTI-------DGEKYSLMRVRLLTGRHHQIRVQFSHHGYPLYGDIKYNSDFRNRRDVSP------ALFAYHLSFKNPVGADRITVEA---------------------------------------
>UniRef50_C8PSH6(12-236:240) Pseudouridine synthase n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PSH6_9SPIO  E=9e-38 s/c=0.71 id=30% cov=82%
-LDILYEDPSLIVINKPSGLLSVPYQGSSVRTAADILERimrskgAYSKHHRPFAVHRLDRDTSGVMLFALNERTKDEFMRSWHTLVTERIYRAVaenpAEGGLADSGIIDAPLAYNAYNRAFVPTAEKHahfDTVAARTRYKIIER-----------GAAYTLFELSLDTGKKNQIRAHLAANGYPIAGDPI--------GHARTDPFGRLALHARSLAFTHPVTRKVMRFEVPEPEAWLAYI-----------------------------
>UniRef50_B6JZY3(105-286:401) DRAP deaminase n=1 Tax=Schizosaccharomyces japonicus yFS275 RepID=B6JZY3_SCHJY  E=2e-37 s/c=0.87 id=27% cov=67%
-VRIVHEDEEYVVIDKPAGIPVHPTGRYNHNTVLHILMHENKCPL-LYPCNRLDRLTSGLMFFSKTPKGAERMRVHMISKDLQKEYVARVVGEFPAEKTITCDAKLLTVAPTLGLNRVHPDGKDAVTIFKRLA-----------FDGHTSLVHCKPLTGRTHQIRVHLQYLGYPIANDPIYANLR---------------------------------------------------------------------------
>UniRef50_B9E7W2(73-268:273) Ribosomal large subunit pseudouridine synthase homolog n=4 Tax=Staphylococcaceae RepID=B9E7W2_MACCJ  E=2e-37 s/c=0.81 id=32% cov=75%
MCEVKYEDEYLAILVKPKGVKTHPNDMSESNTLLN-HAIYTLDSEYVEPIHRLDQETVGLLLVAKNPFIKKILDRMLEERLIKRTYRAKVKSHLPlKHQTIDMPIGKDKFHPNKR--RVSQTGDRAVTHI----------VSSKANRDGTADVELQLETGRTHQIRVHLAEIGHPVIGDPLYSDSH----------LRQLALESYKLEFIHPFTGETVT------------------------------------------
>UniRef50_Q86P70(377-546:739) RH45372p n=20 Tax=Neoptera RepID=Q86P70_DROME   E=2e-37 s/c=0.93 id=31% cov=65%
-IKIVHMDEDIVVVNKPASIPVHPCGRYRHNT-VVFILAKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEGVFPDGIVECKEPIEVV-SYKIGVCKVSAKGKDCTTTFQKLSQ-----------NGTTSVVLCKPLTGRMHQIRVHLQYLGYPILNDPLY-------------------------------------------------------------------------------
>UniRef50_Q2S1S0(3-214:232) Ribosomal large subunit pseudouridine synthase A n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2S1S0_SALRD  E=2e-37 s/c=0.75 id=29% cov=81%
---ILHRDEHLLVVSKPPGLLAQPDQTGDPDVVSRgkeMLSDETEGAPFLGLVHRLDRPASGVMALARSPEAARELSRQFRERLVEKRYVVAVEGTLQGIGAWTDYIAK-PDRQPRLVDPDHPEGKRAALDWQVLESSSA-----------HTLLQVTLQTGRSHQIRLQAASRGHPVVGDDRYGASDSLPDRAV-------ALHHVLLRADHPARPRRETFVAPPPTHWSGVL-----------------------------
>UniRef50_D0KW62(23-221:222) Pseudouridine synthase n=1 Tax=Halothiobacillus neapolitanus c2 RepID=D0KW62_HALNC  E=3e-37 s/c=0.79 id=28% cov=77%
----LAETADFLIIAKPTRMLTQPG-KEAHKTDSLITRVNQEF-PEARIVHRLDWDTSGVMVLARHARAHRALSIAFQDRRTKKCYIAHVDRAPAPPQGLIDRPIGSDREHRPRYRIDEEQGRPSQTRYVVL-----------NETADFARLALEPITGRSHQLRVHLLSIGHPIQGDTLYHPHAQNHA--------RLMLHAESLSFPDPASGITQTFSDPVP------------------------------------
>UniRef50_Q28C59(50-321:324) RNA pseudouridylate synthase domain-containing protein 4 n=1 Tax=Xenopus (Silurana) tropicalis RepID=RUSD4_XENTR  E=5e-37 s/c=0.57 id=29% cov=89%
---VVREDPELVLVNKPHGLPVHGGPTVERSVASLLPALAKHhfgwKAEPLKLCHRLDRDTTGALILARTTEAAERVQQALREREVHRVYWALCLGTPsPREGILDIPIMEKETSGPQKHYKMALSPRFRVSEEGAVERVRVPRSAHEavtryrtlGAASGASLVELHPITGVKHQLRVHLAlGLNCPILGDHKYSHWGRLAPQKPPDSVLRalgltvpqartlsLHLHAVQLTLPSSDGSTPIVLQCPLPYTFRKTLRKL--------------------------
>UniRef50_Q5M721(97-368:369) RNA pseudourine synthase 5 n=13 Tax=Embryophyta RepID=PUS5_ARATH   E=6e-37 s/c=0.57 id=31% cov=83%
-LEVLYEDDDLIALNKPSGLQVLPGGLFQQRTVLTQLQwcfgkndsyIGSRESPHPVPVHRLGRGTSGILLCAKTKLAKTKLAAYFAEgtslvgsgnldqecgtgRKLSKIYRALADGIVEEDEVVIKQPIgvVRYPGVAQGLYVASPEGKPAFSKVFVLER---------DREKNCSLVKVEIQSGRPHQIRIHLAYMGHPLVGDPLYvaggqpkcfdpdlvddaaafaEDGGYRRPNQAVPGDCGYHLHAHQVELPNLLnTHKVVKIVAPLPP-----------------------------------
>UniRef50_D0RNQ1(95-287:288) Pseudouridine synthase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RNQ1_9RICK  E=7e-37 s/c=0.81 id=22% cov=74%
----VFECEDYCVLNKPYGYASQDGSKVK---LSVIDIL-NSTKKNYYIVHRLDKDTSGLMLLAKNRFYAKKFSEMFKSREVKKKYLVIINGKIK-------------KNKGEIHSKEKVNGKEIESKlyFEVIS-----------KKNNFSYLEIDLITGRKHQIRKQFSDIGHPVVGDLKYGDKKNNTQ---------LCLLSYEIEFE--YNNKIKKYKATIPDNFKTCLEKF--------------------------
>UniRef50_D2MPF1(5-208:225) RNA pseudouridine synthase n=1 Tax=Bulleidia extructa W1219 RepID=D2MPF1_9FIRM  E=1e-36 s/c=0.76 id=29% cov=77%
-IKIIYEDNHLLVVEKPVNVLSQADNSQEDDMVSRLKKLikirdQKPGQVFIGLVHRLDRPVGGLMVFAKTSKGASRLSDSIRCHTFKKIYLAIVDSVsLPQEGTLEDYLYKDSQKNR-VFVVDAKKGKLARLHYQVLA-----------KKRGKSLVRIVLETGRPHQIRVQFASRNWPLVNDQRYHPHPNRGS---------ICLFAYQLSFPHPTKREEISFQ----------------------------------------
>UniRef50_A0RRU2(68-300:319) Pseudouridine synthase n=2 Tax=Campylobacter fetus RepID=A0RRU2_CAMFF  E=2e-36 s/c=0.67 id=31% cov=75%
-LKPIFECDEFGVFDKPSGVLSHPNGRNCEYSLC--DEIWSLWGKKACVAHRLDRETSGVIVVAKNANSALNLKKSFENRAVAKTYLAFVRGKFDGNGLDKFHindfedfkdkleffdniqgfvidknmdITKDYDDIKIRMEICPE-GKRAVTVVKLVEY---------YPKFDISLVECYPLTGRQHQIRLHLFHMKHRILGDPIYGLDKFNveqildgvmseRDRVKNTGASRLMLHAKSVKF----------------------------------------------------
>UniRef50_B7G0Q3(3-198:200) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G0Q3_PHATR  E=2e-36 s/c=0.79 id=35% cov=75%
-----YQDRW-VCVNKPAGMSTHRSGGNRSNQFVVSTLLKRQLSRKVFPVHRLDHRTSGALLFAFDSEMCASLHDALREQSARKTYVCLVRGFWDNFFESDTA-------TVDKALTVDGTKRSATTVFTKLASTIILNNSAYGEKNvpiSCSLILAVPTTGRTHQIRRHASAMGMPVLGDTQHGETKVNRWWRQKRGLDRLALHCLSL------------------------------------------------------
>UniRef50_B0S254(73-273:273) Pseudouridine synthase n=2 Tax=Finegoldia magna RepID=B0S254_FINM2   E=2e-36 s/c=0.77 id=29% cov=78%
-IEVLYEDDDIFVLNKPDKLTMNKDGEKSLANFVSYLFEQRNIKQKVRFINRLDQDTSGVVMVAKNKIAQAYY----QKNSFKKKYLAIVKGNPK-----DQKIELNLKRDGIKTEI-DENGKKSVTILENLKNY-----------GDYSLVSLELLTGRTHQIRVSMEYINCPIVADSLYGEKIENFT---------QMLHANEIEFVD-MKGEYHNITTNLPQRFKDYLKE---------------------------
>UniRef50_Q7MA82(79-288:308) Pseudouridine synthase n=1 Tax=Wolinella succinogenes RepID=Q7MA82_WOLSU  E=7e-36 s/c=0.73 id=34% cov=77%
----------FALFDKPADLLVHPKGTFEHYSL--MDEVRLRFGQEADLAHRIDKETSGIVLITRSKKEGAILKINFFNREVKKCYWALVRGKMEGERILDFPLKAQSKRlDLGVRMRVDEKGKSSLTQIKALDY---------EALSDTTLVEASPLTGRTHQIRLHLAHAGYPILGDPLYGTSDElsrayleqamdQEERRRCFGASRLMLHAQGLGF--PYKGSWYEIVS---------------------------------------
>UniRef50_B0ME87(84-322:329) Pseudouridine synthase n=1 Tax=Anaerostipes caccae DSM 14662 RepID=B0ME87_9FIRM  E=8e-36 s/c=0.64 id=28% cov=76%
-LSVIYQDSNVLIINKPYGMLSQKAkpSDISVNELIVPYCLEHGILKesdlelvRPSVCNRLDRNTTGLLIAGISLEGLQTMAEVLRDRSVRKYYYCIVKGMVNKKTRISGYICKDHRENKVSFSeRKISGGSRIETAYEPMA-----------AGHGFTLLRVELITGKTHQIRAHLAGMGFPLAGDTKYGDRGVNLQMKQKFGVKHQLLHCGCLEF----------------------------------------------------
>UniRef50_A2R658(127-290:484) Similarity: patentmatch against protein AC A46560_1 Trembl n=1 Tax=Aspergillus niger CBS 513.88 RepID=A2R658_ASPNC  E=3e-35 s/c=0.92 id=30% cov=63%
---IIHEDDDLIVIDKPAGVPVHSAGRYHYNSVLEIMRSQRHPEWVPRPCNRLDRLTSGVMFLGKTAKAAENMTGKLKARTLQKEYVARVKGKFPDgVIVCDQPIMSVSPKVG--LNRVRATGKEAKTKFRRLA-----------------IVHCLPLTGRTHQIRVHLQFLGHPISNDPIYSNRK---------------------------------------------------------------------------
>UniRef50_A4S8Z7(14-320:321) Predicted protein n=2 Tax=Ostreococcus RepID=A4S8Z7_OSTLU   E=1e-34 s/c=0.48 id=34% cov=85%
---VLHADEHVTVVDKPPGLATTRGNGVD---VSVYDLRHALDSE--YVVHRLDRDTSGVLVLARTAFAANRLNAMFAKKSrmdfteimradmergdapslsndpVVKTYWALTSNPPPrgaRSGWIEAPLTEVGDGDGYSTARlvggwrvydakgggvvvgtgesmrdksndaGSPASKAAMTHFKVLASAGEDGP---------TLLELTPITGRKHQLRVHLAkALSSPIIGDYKYGFNDRRAPWKSRFtdiesadvesekesdfwrKLRRaslrgvskipLHLHARALQFVHPESGVSTRVVAEPPPHFAAALRAFDLK-----------------------
>UniRef50_C6AMS1(3-200:238) Pseudouridine synthase n=19 Tax=Proteobacteria RepID=C6AMS1_AGGAN   E=1e-34 s/c=0.75 id=32% cov=70%
-FQIVFQHPDFIVINKPNGISVHKDHADVGLTRLVAQQL---GVPQVWLVHRLDKVTSGLLILALNEKAAVTLSRKFAEHQIQKIYLALSTQKPKKKQGRISGDMQKARRGAWKLCQSKEN--PAITDF-----------VSHSLAPNLRLFILYPKTGKTHQIRVAMKSLGSPILGDELYGGEV----------ADRTYLHAYQLSF----------------------------------------------------
>UniRef50_A4BGF0(95-297:309) Pseudouridine synthase n=1 Tax=Reinekea blandensis MED297 RepID=A4BGF0_9GAMM  E=2e-34 s/c=0.73 id=27% cov=78%
--DILYEDEQILVVDKPHFLSTTPVGQFMKHTVT-TRLRNRTGNMAITPAHRLDRATAGVLLLTKQRAVREAYQSLFLRREVEKTYHALCHPNPELPEQFEINLHLKENTD-NMFVRVLDAPPNSHTSAKRLARHSTGD-----------LYELRPSSGRKHQLRCQMAHLGAGIVNDIWYPVAQDPSPDDFSRPLQ---LLAKKLAFIDPFSGQRREFVS---------------------------------------
>UniRef50_A1SV26(85-290:303) Pseudouridine synthase n=3 Tax=Gammaproteobacteria RepID=A1SV26_PSYIN  E=3e-34 s/c=0.71 id=27% cov=78%
---ILFQDEHILVAHKPHFLAVTPGGKYVNECLQN-RLRRSTGIEALQTLHRLDRVTAGLVMFSVNPDTRHRYHQLFKTRQIHKSYQAIASISDAENLTGQEWEIKNRivQGEPRFRMRVTEGEANSHSVIRCLRQ-----------SAQTALFELTPVTGKTHQLRVHMQALGLPILNDKYYPQLEPLSADNYAAPLQ---LLAKELQFIDPVTEKPRCFRS---------------------------------------
>UniRef50_A8SPE4(90-330:334) Pseudouridine synthase n=2 Tax=Clostridiales RepID=A8SPE4_9FIRM   E=3e-34 s/c=0.61 id=27% cov=78%
--EIIYHDHNVLIVNKPVGVLSQKASKDDYsiNESVLDYLLDNGYITseqlrtyKPSICNRLDRNTSGLVLCGVSLMGNQELSRIIRERNIDKYYYTIVKGHIKSVQDVTAYLVKDEKKNtvIVRDGVDEIKQDSGKNEFEKIHTIFEPV----RSNGKYTEVKVKLITGKTHQIRAQLSHMGYPIVGDQKYGDRETNIYFRQTYKLRNQLLHCGEVKFT---------------------------------------------------
>UniRef50_Q6F9V8(96-298:304) Pseudouridine synthase n=17 Tax=Acinetobacter RepID=Q6F9V8_ACIAD   E=5e-34 s/c=0.72 id=26% cov=78%
---ILFENHDLLVVDKPHFLTISPTGKYVQETLLV-RLKQQTGNEDLTPIHRLDRETAGVVLFCKRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQTLRLCLEKGNPFYTMQVNPNGQVNSETRIECLAH-----------NQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFYPVVEHKADDDFSAPLQ---LLAKELSFFDPITQSPLNFKS---------------------------------------
>UniRef50_A9SET3(56-311:327) Predicted protein n=2 Tax=Physcomitrella patens subsp. patens RepID=A9SET3_PHYPA  E=5e-34 s/c=0.57 id=26% cov=82%
---VLFEDEWLIIVNKPRGLYS----GHVFETMPSLCSSSGETPLHLHMANRLDRDTSGIMIITKCKVAAANLTRSYMNRKVHKTYIAQCAQSQPTWRKSRiesghgrsrygAWHVYAKHDIGRRLPVKTETVREMITRLEIVSgpdslrwdnelsvehdclevivgsedevrlVSNEVTKRCSDVDEEVTLVRAFPETGRTHQIRLHCQYLGLPLCGDVKYGGPLFWQSVHYDSHT----LHAESLALRHPMTNQLLQVVAPYP------------------------------------
>UniRef50_UPI00015B45C3(20-222:272) PREDICTED: similar to conserved hypothetical protein n=1 Tax=Nasonia vitripennis RepID=UPI00015B45C3  E=8e-34 s/c=0.72 id=30% cov=75%
-IEILHQSDNFLIVNKPYDMVINSNNPSVKSVQLIIRemfpnLVNPNLYHEFYFVHRLDYATSGVMCLALNKQSAQAASSAFEERTVRKYYLALVHGHIdKYSMVIDIPIGhdvRELNGNRKMCTKDDDFCEKARKSCTALLVLE----KGYIDDRPVTKVLLYPKTGRRHQLRVHCAHIGHIIVGDYTYSGKTDTKP-------HRTFLHAFRL------------------------------------------------------
>UniRef50_UPI0001BCD7D0(60-264:283) hypothetical protein AmarD1_17996 n=1 Tax=Aeromicrobium marinum DSM 15272 RepID=UPI0001BCD7D0  E=9e-34 s/c=0.71 id=29% cov=79%
-LTVLHRDERLVVVDKPAFLSTIPRGRHVAQSVVV-RLRDELGLPELSPVHRLDRVTSGVLVLTTERRWRGAYQGMFQHRRVHKAYRALAPLRPDLELPLTVRNHLRKDRGAWQVTVDPDAQPNAETLVELDAVV-----------GGLGVYRLTPRTGRTHQLRAHLCGLGIPIVGDPLYPAVLEVDVDDFSTPLQ---LLAHEVSFTDPVDGGERRFTS---------------------------------------
>UniRef50_C3ZJW0(12-230:244) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3ZJW0_BRAFL  E=2e-33 s/c=0.66 id=30% cov=79%
-VEVLYRSGNFLVVNKPYDVVL--NWDDPSRTDTLQHLLQERFPdlvdqslkHCFRFVHRLDYSTSGPICIALNKKAAGHAGKAFSQKQVIKQYLALVRGHISEDHLsINKAIGEQGTPDAPVPMCVEGTPgcqhlRDAVTQLTVVEK-------GLYEGQPATKVNLCPMTGRRHQLRVHCQSIGHPIVGDYTYSCRQDTTPY-------RMMLHAQRLVI--PLKGEVIDIETDDP------------------------------------
>UniRef50_C3WCY4(90-292:292) Pseudouridine synthase n=1 Tax=Fusobacterium mortiferum ATCC 9817 RepID=C3WCY4_FUSMR  E=2e-33 s/c=0.71 id=22% cov=66%
---IVYEDDRVLILNKKANMVMHKGSGHEYGVSEILKEYLN--NPNFNFVNRIDKATSGLVVGAKSLVVTRELSEEIRERKVDKKYYILVEGKVKRREFQIKSYLKKLEDKVVELEQYEEGAKESLSFFKVVEY-----------GKNCTLLEGTLGSGRTHQLRVQLASMGNPIIGDSKYGKGKE--------------------------------------------------------------------------
>UniRef50_B3PHH1(118-296:347) Pseudouridine synthase n=3 Tax=Gammaproteobacteria RepID=B3PHH1_CELJU  E=5e-33 s/c=0.80 id=32% cov=69%
------EQEDFLLVYKKPGVSFHSEQGEPG---LFEIIRQRGGYAQLYPVHRLDKVTSGLLVFAKTAEANHQLCAQFEQRLTQKYYLAISAGKPIKKQGLIKGDMYPARRGAWMLGRTLEN--PAITQF-----------FSQGLGNGQRLYVLKPHTGKTHQLRVALKSIGAPIVGDSLYGDR--------HAGIDRVYLHAFSLAFT---------------------------------------------------
>UniRef50_B0EHA4(138-303:389) Ribosomal pseudouridine synthase, putative n=2 Tax=Entamoeba RepID=B0EHA4_ENTDI  E=7e-33 s/c=0.86 id=31% cov=64%
LLPIIHEDNDVIVVNKPSGIPTHSGGRYTENTVINI--LEKERNIKLFGVHRLDRLTSGVLIIAKSSEIANEIQRHFIS--AHKKYICRVIGYMGSCIVNK--PIIETTCITKQRVTVGSEGKISTTIFEQIQY---------DQKTDTTLLWAIPKTGRMHQIRVHLSYENHPIANDSMY-------------------------------------------------------------------------------
>UniRef50_C3XCW5(97-305:319) Pseudouridine synthase n=2 Tax=Oxalobacter formigenes RepID=C3XCW5_OXAFO  E=1e-32 s/c=0.68 id=25% cov=80%
---VLYQDDWLVVADKPHFLPVTPSGKYVSETLLV-RLRKKLGIDTLTPIHRIDRETAGLVLFSVKPEGRNLYQRLFRENFVSKHYEAIAPYRDDIAFPMRYRSRIEEGDSFMRMRVIPDGTPNAETEISI-----------QQKSNAFAHYHLKPVTGRKHQLRIQMCSLGIPLLNDRIYPVHLPEAVTDEMQAEEfryPLQLVAKSVSFKDPVSEKIHHFES---------------------------------------
>UniRef50_B6K9V8(1910-2166:2780) RNA pseudouridylate synthase domain-containing protein n=3 Tax=Toxoplasma gondii RepID=B6K9V8_TOXGO  E=1e-32 s/c=0.55 id=25% cov=88%
--DVLWEGDGLTVIDKPPGWhcsdvrydpqtesrqlccIVSSSRPEPLGLYCSLRFNYPTGKLKecnFGLGHRLDVDTSGPIIIAQTLEAWQWIRDQMHKRNISKEYICLCHGTLAEGFHVIDSPIITSTDGRRLQSYIHHAGQPSLTVVKPLAHLEHRELRYPGSTTPlqFTLNWVKIHTGRTHQIRVHLQSLLdsrgrpHCLVSDDKYGNGQQVEDFQ---WCRRLFLHQHRLSFRD-LNDTPQCFVSPLRADLLSALRHL--------------------------
>UniRef50_A4S7H5(47-311:318) Predicted protein n=2 Tax=Ostreococcus RepID=A4S7H5_OSTLU   E=5e-32 s/c=0.53 id=28% cov=85%
----VYVDDDVYVLNKPAQTYVHDIERlvergmvkcDDATTVDNRATTRDvpfNASESARVVHRLDRDTSGCLVVARNRDAIRSLSAQFADGTVQKTYVALCAATADYDGVEDHRRVFTGWGRAKYglfrlydaadigralPGNKKVKVKHAETTIIVERVITDGVALRfcepptaddaDRRRHRVALARCSPLTGRTHQIRLHCASLGLPLVGDVRYGGPiaaTRDGPIDAPFSARRVAgalLHAERVAFRHPKSNLRVDVHAPRPP-----------------------------------
>UniRef50_Q73MW9(89-295:305) RNA pseudouridylate synthase family protein n=1 Tax=Treponema denticola RepID=Q73MW9_TREDE  E=7e-32 s/c=0.67 id=25% cov=78%
--DVLLKTDDLLFINKRSGELVHGEKSLCEAVLKYFPSKEKSLSFKVGALHRLDKDTSGILAFSQSLKGAQGFSRALQEGKIGKFYIGITEGRPSLSEFKSI-----------------IDGKECLCLIRILD---------FSKEENLSLVLFNLITGRKHQIRIQCSQFGTPLLNDKKYGSKQKKAFSEDLSKKTTYFLHAYKLIFSEPFLDDlPKEITAPLPENFKRA------------------------------
>UniRef50_C6C294(81-264:292) Pseudouridine synthase n=1 Tax=Desulfovibrio salexigens DSM 2638 RepID=C6C294_DESAD  E=1e-31 s/c=0.76 id=28% cov=66%
-LPIIYEDDNYLAVCKPAGLPTQGGTGHDDSVADRLLSMFADAHYKPAPAHRLDRDTSGVILAGKSHQGQKDLSDFFAEHgEGGKFYLAEVEGRWPEEDWVELHDKMEKSGSKGREKVVVGSGKDA-----------SSSVCPVTIGEKSSLLIVKLHTGRTHQIRVQLSSRGFPIAGDVKYGG-----------------------------------------------------------------------------
>UniRef50_D1KBQ5(92-268:277) Pseudouridine synthase n=1 Tax=uncultured SUP05 cluster bacterium RepID=D1KBQ5_9GAMM  E=2e-31 s/c=0.78 id=32% cov=66%
---------------KPAGVFSQGSKWGDHCALT--RLVEKKLDRPTFLVHRLDRATSGLMLIAHTKNMARDLSKMFADRNIDKTYLAIVEGKFTKEKITLEKPI---------------DGKNAVSHVTLLESEKFK-----------SLLKVKIETGRKHQIRKHLSEFSHPIIGDRLYGNAAKNHPED-------LQLQAIQLIFNCPIDKQTVKIK----------------------------------------
>UniRef50_A1SUH8(16-211:242) Pseudouridine synthase n=3 Tax=Alteromonadales RepID=A1SUH8_PSYIN   E=4e-31 s/c=0.70 id=26% cov=72%
-FSVVHENNEFIVINKQAGINFH-SEDGEFGVVVAA---EKAFSCKLYSVHRLDKMTSGLLLLAKSSPSAAQLSALFFEHQIQKYYLAISDKKPKKKQGLIKGGMEKSRRSMWKLTKQTNN--LAITQF-----------FSYSLENGKRLFVIKPRTGKTHQIRVALNSIGSAICGDPLYAEKSPQSAA-----FDRAYLHAYQIDF----------------------------------------------------
>UniRef50_B8LRV2(65-357:358) Putative uncharacterized protein n=1 Tax=Picea sitchensis RepID=B8LRV2_PICSI  E=5e-31 s/c=0.46 id=26% cov=86%
----IYEDEWMIAVNKPSGVYCeHVLSSIPEllaSSPSSAGAANDVNPLELHLANRLDRDTSGVMVITKLHKIAGQLVKAFTDRKVRKTYLALCIGPaPKWNNIYIESGHGRSKFGAWRVYSRTDVGrilpggtvvREMATHLKVLAvnanhrmhrdsvdkaqnssqgiafdlkedrfatvgdngstdsiekvvvteqnskapgQDRDIVSSPNIRKNDEVLIRASPLSGRTHQIRLHCQYMGLPIRGDVKYEGPHIWKGITYAN----HALHAESLCFEHPVTNNMVKFHAPLPQWVMEA------------------------------
>UniRef50_A1V9V4(131-320:390) Pseudouridine synthase n=3 Tax=Desulfovibrio vulgaris RepID=A1V9V4_DESVV  E=6e-31 s/c=0.72 id=28% cov=72%
--PVVAETPDLFIFDKPAGLAVHPGTGHTDSLTTRLAQHFAKAPFMPTPAHRLDRDTSGLLLVARSYAMLRTLHEAFASHDaLVKEYLAWVAGcwQPAAPVTLHDRLSKGAEASGFERVASDDEGAEAACTVRCLLR-----------EQHRSLLLVTLHTGRTHQIRVQLSRRGHPLLGDRKYGGPPRMGGF---------LLHAVRLCLP---------------------------------------------------
>UniRef50_B8DML1(157-381:393) Pseudouridine synthase n=1 Tax=Desulfovibrio vulgaris str. 'Miyazaki F' RepID=B8DML1_DESVM  E=7e-31 s/c=0.60 id=28% cov=74%
--------EGLLVLLKPAGLAVQPGTGHDDCVTARLAAQYAGADFLPTPAHRLDRDTSGLLLVATSYARLRALSDAFAAREgLVKEYLAWVAGRWPHEGARTLHDRLEKQGAPGRQKVRRVGGEGSVPRaasgneaVRVESgtdaahaaagadagRHAACTVTPLRRGDGASLLLVRLHTGRTHQIRVQLAERGHPIMGDRKYGGPACG---------QGMLLHAVRLTLP---------------------------------------------------
>UniRef50_B8J0V1(122-306:360) Pseudouridine synthase n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 RepID=B8J0V1_DESDA  E=1e-30 s/c=0.73 id=27% cov=63%
---------YLWAFDKPAGLPVHPGTGHEDSLTTRLSCHFAGVSFMPTPVHRLDRGTSGIILVAASYAALDETQRALRANAMHKEYVAWVAGRWPHTQTCLVRHFLRKEavdgfERVRPVKADAPDAKEALCLVRALSIAD-----------RASLVQVRLLTGRTHQIRVQLSSLGHPVLGDTKYG------------------------------------------------------------------------------
>UniRef50_Q04RC2(8-258:277) Pseudouridine synthase n=4 Tax=Leptospira RepID=Q04RC2_LEPBJ   E=2e-30 s/c=0.54 id=24% cov=83%
-IRIFYETESFLFAEKPPGIPVHATKDSKRENF--ADRLQEQLSlEYLRTVNRLDLDTSGLVFLCKNPDKNKEADRILKSSS--KIYLCVADGIVEEEHFTETCYIKDGNKKVRKVF---SGGDKAVTEFLTLKR---------NLKDHYSVLLAKLHTGRRHQIRLHLSEKGHSIVGDYVYGKSLDLNSTTKRKPMetspsdnrisniqkrnflnketitapirakrrvsfaQRSLLHAIGVSFRNEGGYEERIF-CPPPIDFQKFLE----------------------------
>UniRef50_A2EYQ7(118-345:353) Ribosomal large subunit pseudouridine synthases, putative n=1 Tax=Trichomonas vaginalis RepID=A2EYQ7_TRIVA  E=2e-30 s/c=0.59 id=29% cov=78%
------ETDNYVAYLKPASVTVNTVGGYFYNSMV------KRLPPHLHVVHRLDRVTSGIIVFAKNKAAATNFNQYLVGEKVSKTYIARVIGRFPKgEIICDQPLGTDFNLHR---TVVTPTGKPSKTIFKLLKT-----------NGKESIVEAHPITGRTHQIRCHLQYLGYPITNDEMYGGKREVYTKEMKDALKkaeklglwpcdycqdktnprvefQVYLHSC-----HYQTPE-FDFHAPMP-DWED-LDKFGLK-----------------------
>UniRef50_C1N0H2(123-362:497) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1N0H2_9CHLO  E=3e-30 s/c=0.56 id=27% cov=73%
--------DDLVAIHKPATMPVHPTGQYRKNTVLGYLAAHRRDLGKLFPVHRLDKNVSGLLVMARTPTTANAMRTQVEGREVSKEYLALVTMKIFNAGGNAETVAAAALTAFAREegtdvfaarcdaavayderarvascdVSVADGAKDASTAFELVARGEWGVGGGDGGGDGGSacpfedvvvrgglprralLVRCRPTTGRTHQIRAHLSRLGWPIVNDVKYGGARAADLGGDALALD---------------------------------------------------------------
>UniRef50_Q25346(167-402:413) Pseudouridylate synthase-like protein n=7 Tax=Trypanosomatidae RepID=Q25346_LEIMA  E=3e-30 s/c=0.57 id=23% cov=88%
---VLFKNEHVIVINKPSGVPIMPTHDPLAMNITdLLPAWRYTNTQTPVICHNLDTETSGCVVLARSANTHRMLGRMFVKRVVPNsVYWGFAVGKPPVNFGRIRMHFEVQKGQGGDVIV----ARPTPTADSKVGIAEFVVNASALEFG--SFISFYPLTTRRHQERIMAAHaLRAPLLGDAKYGGESAFPHSLSLFWDParkdvPLHLHHRKIQLPYKNGaGEFVCVTAPLPPHMEKTFKRLGW------------------------
>UniRef50_C5BI24(1-231:231) Pseudouridine synthase n=1 Tax=Teredinibacter turnerae T7901 RepID=C5BI24_TERTT  E=4e-30 s/c=0.58 id=24% cov=87%
---IVDEQPGFLLIHKYPGAVVHGTADSGEITLT-QSLRHDFSCKSLFPCHRLDRTTSGLLVVAKGEAANKYFSTLFEKRAIDKCYLALSAKKPAKKQGAVRGDMVKARNGSWMLTRSLNA--PAHTQF-----------FSKGGVEGKRLFVLRPITGKTHQLRVAMKSLGAPILGDERYGGGD----------ADRCYLHAFALQFS--VDGNEYSYVCP-PEHGDLFCSQ-NFKSALDDLQSPfELPWPAAKNGQ---
>UniRef50_UPI00016C3B11(5-199:204) ribosomal large subunit pseudouridine synthase D n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C3B11  E=7e-30 s/c=0.68 id=32% cov=63%
----------------------------------------------LGVVHRLDKPVSGSLVFARTSKAAARLSEQFREGGVEKVYWAVIEAQAPGPWVTadngslEDWLQKDDDNARvETVAPETPGAQFARLLFQV-----------RGRHNGLIWLELRPHTGRKHQLRVQLASRGASIYGDHKYGSKLPFG--------NGIALHARSLTFLHPTSKNPVTVKSEVPKIWR--------------------------------
>UniRef50_Q54VB9(193-624:746) Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum RepID=Q54VB9_DICDI  E=9e-30 s/c=0.31 id=27% cov=87%
-LDIVYEDKDLAIINKPAGMLVHPTaltlgsnalvinKEDQTHTLVNALIHRYggvenlssvGGVERPGIVHRLDKDTAGMIIIARNNDVHQKLQTLFEKHtstmithttidqyedngsisnnqiermlqgkkiplTISKKYHCIVLGKPKEQHGFINKKISRHPADKNKMVIDQDNGKEALTEFKVLKVWENVNAKVLDNQKNkqtskqqtttnnnnnnntttnniinstlseydnamnqlhknkkkntkksnitsknvnsrmqflsvddddeeekedgdedekededeeenedeedeeeeddeeedeeeeeeddddedeeeeeddeeeedeeenydeiilrlqqktkmitsntFSLLEVTLHTGRSHQIRVHMASENIPIVGDPIYSSK------SKQFLVSYLLLASMNLKFVHPILNEIKEFSIQYPSHFKNFIS----------------------------
>UniRef50_UPI000180B18D(183-370:456) PREDICTED: similar to RNA pseudouridylate synthase domain containing 2 n=1 Tax=Ciona intestinalis RepID=UPI000180B18D  E=9e-30 s/c=0.70 id=30% cov=65%
-VEII-EDNSkYVVVNKPSSIPIHPCGRFRNNSLV-YILAKDLGYQGLLGCHRIDRLTSGIVIFGKTKNIAHKVAKEISERKVEKQYVCKVVGEFPsTDIVCNEPVSLFNRKLGYAVAWKVEGvvGKEASTWFTRMSY-----------DGTNSVVLCKPKTGRTHQIRVHLQYLGFPIINDPIY-------------------------------------------------------------------------------
>UniRef50_B0ENH6(104-377:378) Ribosomal pseudouridine synthase, putative n=4 Tax=Entamoeba RepID=B0ENH6_ENTDI  E=1e-29 s/c=0.48 id=27% cov=73%
----------FLVINKPSGIPVHPTGRYNQNCILNILLNEHHFS-HLKPVYRLDKNTSGVLLFAKTKKFASSFQSFLKEKssvfsspsSLQKIYLARVVGYFPDFIEVNLPLH-LIRFGTESQNSICEDGVEAKSSFKRL---------FFDKDSNTSVIECIPHTGRTHQLRLHLKAINHPIANDSAYllnqihnyrqqdGDFIRENKWREKYGWvfdkdcndcnfpkgdpieDQIWLHAWKYSFN---------------------------------------------------
>UniRef50_C4GD18(5-307:312) Putative uncharacterized protein n=1 Tax=Shuttleworthia satelles DSM 14600 RepID=C4GD18_9FIRM  E=2e-29 s/c=0.43 id=28% cov=78%
--EIIYEDADIFVCYKPAGFATQTASALQADLVSELKNYRKSRGEsdYIGLIGRLDQPVEGLMVIAKNPRAAGKLEAAQAKGRIDKYYLALTQGLPKgpdcgqeadslhrkgeWIFLENDMLPASRGKNGRLLAPEDKGTKNghqpapedkgtknghqpavkdkgakktrlpapgtgeaktacqlapgtgeakkacllapgikgarkARLEYQILDHSKTK------DGRALALLRVHLLTGRRHQIRLQLSGLGSPILGDARYGADPNGQP---------LALCACQLSFPHPGTGERISYE----------------------------------------
>UniRef50_A4S4W6(1-178:178) Predicted protein (Fragment) n=1 Tax=Ostreococcus lucimarinus CCE9901 RepID=A4S4W6_OSTLU  E=4e-29 s/c=0.73 id=26% cov=63%
---VLYENDAVVIVNKPPGVSFH--SEFEPGALARLRASRDAREERLRAVHRLDKGTSGTLVFAKTADAAKKLSDGFATRAIVKYYVGISGKKPKKKMGTVTGDMARARRKAYKLTNTKDN--PAVTKF------------VSFGAKGRRMFIFRPLTGKTHQLRVCAKSLGAPLLGDDVY-------------------------------------------------------------------------------
>UniRef50_Q7PQ70(52-282:300) AGAP004401-PA n=4 Tax=Culicidae RepID=Q7PQ70_ANOGA   E=6e-29 s/c=0.56 id=29% cov=84%
-VDVLYTSGNFLVINKKHDLLINSNDTKKKTVQTIMRkqfpeYVQDNLTHDFYFAHRLDFATSGILCIPLNKNACKEVCQVFEEQRARKYYLALLRGHTDFDeEVIDIAIGEDVRfkDTSKKMCTILEDelcqnPRRSITKVLVLDR-------GYYNGKPVTKVLLRPITGRRHQLRLHCSQIGHVIVGDYTYSLKIDTSP-------PRMFLHAFRLVL--PNTIENLDIQTDDP--FTEKALKYKWK-----------------------
>UniRef50_A7AQ79(154-365:465) RNA pseudouridylate synthase family protein n=1 Tax=Babesia bovis RepID=A7AQ79_BABBO  E=7e-29 s/c=0.61 id=26% cov=68%
-VRILHEDDDYIAVSKPSSLPLYHTGTYYYNTLVEVLknEVFKDSARTLYPVHRLDKLTSGVIILAKSSKAASEFCEGIRNSRFRKVYIARVKGDFTNVFGDHECISINDGIGvgngsvacchGFMRCVSHklsmheftlddtkKDVKVAETRFRMLSYNSSLDE---------SLLLCYPVTGRTHQIRAHLKYLGYPISNDKCYNDGE---------------------------------------------------------------------------
>UniRef50_A8L7E9(13-238:285) Pseudouridine synthase n=1 Tax=Frankia sp. EAN1pec RepID=A8L7E9_FRASN  E=7e-29 s/c=0.58 id=31% cov=73%
----IFEDEAVLALDKPVGVSVM-GERHDTDLVSMAR----DAGEELFPAHRIDKVTSGVVLFAKELRFHGDLTRQFNRRTVEKTYLALTRTRgLPALATIDLPLsvgrknrVRIAANRADIVAWPGPAGTPtpdgpagtpgsdgpagsgarspaswtvpaARTFPNVRSYPSVTRIARVWEGAEHTLVAAYPISGRRHQIRVHLAWVGHPIEGDPLF----------DRAPVTRTFLHSWRLSF----------------------------------------------------
>UniRef50_B7P2L1(14-234:263) Ribosomal pseudouridine synthase, putative n=1 Tax=Ixodes scapularis RepID=B7P2L1_IXOSC  E=1e-28 s/c=0.58 id=31% cov=78%
---VLHLSPHFVVVDKPADVVinTQRPDEHPVTVETLLKRLHPELvdtgvHHSFRFCHRLDFSTSGVLCLALHKQSARSAQRAFHQRLAKKYYVAILEGHVrDDHVLVDSPIGEDKRPqHSHKMCTADKDycvsPRGAQTRLLVLWR-------GLLKGRPATKVLLRPVTGRRHQLRVHCASLGHTIVGDFTYGEDASSR---------RMFLHACRLVL--PTEVETLDVETPDP------------------------------------
>UniRef50_UPI0001757DD8(34-233:274) PREDICTED: similar to AGAP004401-PA n=1 Tax=Tribolium castaneum RepID=UPI0001757DD8  E=1e-28 s/c=0.64 id=24% cov=74%
---IVHRSANFIIIDKAYDLKINSNNRNEETVQTfmkknLPYLASNQLHHEYYFMHRLDYSTSGLMCVPVHKKACQVASQAIQQRKCKKYYIALVRGYLSSNLLDlNFPIGRDNsiTDIEKMCVTHDSNSRSARTLIVVLE-------NGLFENYPSSKVLIRPITGRRHQIRVHCAHIGHTIVGDYTYSNKKDTTP-------ERMYLHSLRLVIP---------------------------------------------------
>UniRef50_A5DTZ4(107-279:430) Putative uncharacterized protein n=1 Tax=Lodderomyces elongisporus RepID=A5DTZ4_LODEL  E=1e-28 s/c=0.74 id=22% cov=66%
-ISVVFEDDDIIVIDKPSGIPVHPTGSYMFNSLSEIVKEMFNFD-NIWTCHRLDKVTSGVVILCKNRDAAVKFLNILleKSDKVKKIYLARVNGKFPDGVYRYTCPILAVNMNGYI--------QPSNLESLLTLTSTIFERVNFDSLSNTSIVRCQPISGKFHQIRIHLRNLGFPISNDLFY-------------------------------------------------------------------------------
>UniRef50_B3RX30(10-219:247) Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens RepID=B3RX30_TRIAD  E=2e-28 s/c=0.61 id=29% cov=74%
-VQIVHQTNSYVIINKPFDM--HINSNEEDVKPTVATQLAELLPTlvdksicfGFRFVNRLDYATSGLLCIAFDKRAANMARKLFEANHVSKKYLALVRGILSRDNGDILVRkaigLDRRDPRGFRMCIPDHNphlcqsPKAAETLIRILGY-------GKYDGEDITKISLSPVTGRRHQLRVHCLTLGHCIVGDYTYSNEVDSKPY-------RMMLHSYSLKIP---------------------------------------------------
>UniRef50_D2VYL5(155-433:464) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VYL5_NAEGR   E=2e-28 s/c=0.46 id=24% cov=68%
-IRVLYHDDEFLVIDKPSSIPVHPAGRFVKNSL--HYLLESALGRKLFLIHRLDKVTSGVLIHTWNAALAKSYQDTMKEGNVRKCYLAQVYGEFPetenMSGEHVLLNGQSFHKDKEGFIHVKNKMVYKQNDWTFIWRADSSENGSDSTDPKntdtaYTLVKriyydpassrsiviAIPITGRTHQIREHLRVMGYPIIND----------------------------------------------------------------------------------
>UniRef50_C3XMA2(103-284:290) Pseudouridine synthase n=2 Tax=Helicobacter RepID=C3XMA2_9HELI   E=1e-27 s/c=0.69 id=36% cov=65%
----IFCNENILALEKPAFLTS-------EEIV--------KSYPQWTLLHRLDKETSGILLLVKeNSSFHLKAKEAFKQLQVLKQYTAIVEGILDEECEITAPLIIKKGKSAKVSISKTNEGQKAITHITPLEIF-----------GKKTKLDIEIKTGKTHQIRAHLAHIKHPIIGDTLYGAK----------PANRILLHARHIAL----------------------------------------------------
>UniRef50_Q73NR9(12-259:261) Pseudouridine synthase n=1 Tax=Treponema denticola RepID=Q73NR9_TREDE  E=1e-27 s/c=0.50 id=21% cov=81%
--EVIFENEAYAVLYKPRGMPTAPLSEDEEGTLVSWFLKRCPEavsvkgkkDIEAGLVHRLDTATSGLVLMAKNQESYDALNLMQGNDLIKKTYVAFTDIDNESDLNADFSRLNLPYRISSQFRSFGPKGKKVLPVFygmrdfsSTAKIYTTNIIDINNLDDSVPRVTCTLTQGFRHQVRAHLASIGLPIYGDPLYnGKFKDFPQEKIEDHSYPLQLYAVGLSFPEP-------------------------------------------------
>UniRef50_B6WPU4(110-303:335) Pseudouridine synthase n=1 Tax=Desulfovibrio piger ATCC 29098 RepID=B6WPU4_9DELT  E=2e-27 s/c=0.64 id=27% cov=63%
-------DGDLWVFCKPAGLPTHPGTGHEDSLSSRLAAGAGDAPFKPTPVHRLDKDTSGILLVAASFAVLREMTTALRERRMKKEYLAWVEGLWPHSGVRLFRHWLRKEagtgNGREQMHVrqtgaPDKGETEALLLVRPVRVEDRRSLLLVRLL-----------TGRTHQIRAQLSSLGHPIEGDVKYG------------------------------------------------------------------------------
>UniRef50_C7NC29(99-301:314) Pseudouridine synthase n=2 Tax=Leptotrichia RepID=C7NC29_LEPBD   E=3e-27 s/c=0.61 id=25% cov=68%
---IIFENEDFFIVNKSEKIPMHKGTGHKYGLAEVFKEIFK--NENINFANRLDFETSGLVIGCKNLKFLRYISQKIRDNEIQKKYFAIVHniknNIESKIFKIENYLTTTENKVIVSENPISKDSKKSITNFKKiliseLKNTKKILDLLEKNNKNVFLLDVDLVTGRKHQIRAQLAHQKIPIVGDKKYG------------------------------------------------------------------------------
>UniRef50_B7G3A4(95-271:271) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G3A4_PHATR  E=5e-27 s/c=0.69 id=28% cov=61%
-----------LVVDKPGTMPVHPSGAYHLNSLLPIL---ENTYGKLYPIHRLDRLTSGLVILGKTPEAARQLGKAIKERdSCTKLYIARVRGRFPFNCASHVPnlssHKSYPPRYGEWSVLQDMDGKKdmkaAETSFALLK---------FDAKSDSSVVLCRPATGRTHQIRLHLQYLGHPIANDPNY-------------------------------------------------------------------------------
>UniRef50_B8BW13(331-588:614) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BW13_THAPS  E=7e-27 s/c=0.48 id=29% cov=86%
-VEILDQGENYVIASKPASVIVHhsswtgkrsdPKRRWKEATP-MLQRVRDATGRRVNLVHRLDRGASGCLVFSFAQneendngetppcSVTKSMIEAMQHPDARKTYLALCDGDGTWNGVDYLNKGWFTFNNP----VKDEWGKlidDCCTDIRFVASKVLPPTSDEDPDNmegrKVSLILARPKTGRWHQVRQHLSSgtIGHALLGDSTHGKSRTNRIWKKDRHLmkERTCLHLSRVQI--PATEYTpaIDISCPLPSDLIKML-----------------------------
>UniRef50_UPI0000E499FC(85-361:373) PREDICTED: similar to RNA pseudouridylate synthase domain containing 3 n=1 Tax=Strongylocentrotus purpuratus RepID=UPI0000E499FC  E=4e-26 s/c=0.43 id=27% cov=88%
--NIVYQQDGIVAINKPPGLGVSGKVNEDDESspltlSSMMSQVADFTDcPSAEIAQGLEKEASGLLLLAENRMAAKKLQSKIKearnRRQFIKTYRSIVCGIPEtKIGVSKMYLGSDvigginmtvGRHNPSGRQIRDGDVWSAETKYRVISENKEL---------GCAFIELQPLRVKRHQLQVQMVNDLCPILGDHTYSHQVQTILGKPILMDPHQALgvHNIQvlspgirkaLAMTRPqvsllplflhlhhvvlpewAGHQDVTITAPLPSHFTRALKELGLRS----------------------
>UniRef50_C7R9V1(100-273:282) Pseudouridine synthase n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7R9V1_KANKD  E=5e-26 s/c=0.69 id=28% cov=66%
------------VWNKPNGVWSQGSKWGDHCSISRLVEEHFDYNRQTYVVHRLDKAARGLLILAHNKEAAAALSAMFAKRTVEKHYLAWVNGQFPHDSITIDKPI---------------DNKPAKSIVTLKEY---------DADKDRSLLSVQILTGRKHQIRIHLSSLGFPIIGDRLHGEPTQSQD---------LQLMAYKLDFQCPITGDK--------------------------------------------
>UniRef50_Q6MNN8(16-225:521) Pseudouridine synthase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MNN8_BDEBA  E=8e-26 s/c=0.57 id=27% cov=72%
-----------IFVDKIAGLNTHTPEYGQRGCVEI---YEEELDRKLYTVHRLDKATSGALVFATSSEIAAQLTQAFEQHKVEKKYLFLTDKKIARTEFTYESFIQKEKNV---FVSRDTQEPNSKTSFKWVKAL-----------GPYQLWEAVPHTGKPHQIRLHAEANGIAVLGDSDHNGTNHF----------RLCLHSQVLGFE--LNGQKVRYETPLPgwaeDDF---------------------------------
>UniRef50_B1VE82(143-420:422) Putative pseudouridylate synthase n=1 Tax=Corynebacterium urealyticum DSM 7109 RepID=B1VE82_CORU7  E=8e-25 s/c=0.42 id=26% cov=84%
-LRLLFQDANLLVVDKPPFMATLPRGQHIVETALV-RARRQFGIPELSPAHRLDRLTRGVLMFTVRPEVRGPYQRLFDERVPEKTYEAVtlpadeapFPPIPRFRGWQEWPAPTPEQPWLLRHHMVKERGRlatylvepeapaidataptdsgaaaaspshdmflappNALTKVVGVRSERRALAIAGGPTPrerRVLVWELVPETGKTHQLRVALRTLGLPILNDPLYEELSDEALRDPTAALPsppfageedfgrPMELTAQRLRFHDPLTGELREF-----------------------------------------
>UniRef50_D1UAP7(83-279:289) Pseudouridine synthase n=1 Tax=Desulfovibrio aespoeensis Aspo-2 RepID=D1UAP7_9DELT  E=4e-24 s/c=0.58 id=26% cov=76%
-LRVVERTDLFAAVYKPGGVHS-AAIAGKDGLSVEAALPALFPDAAPVLLNRLDFPTSGLLLVALGPDGAETYRASEEAGGVRKFYLAVVHGRLDGMISVRNRLDTDDRPRTRALAEEDADAR----------RWTSVNALAHDHDRDTTLVRCLIMKGARHQIRAHLASLDHPIVGDTLYGVPDAATGGEEIGSGPLLHLHHQRIELP---------------------------------------------------
>UniRef50_P45614(82-277:302) Uncharacterized RNA pseudouridine synthase MCAP_0714 n=3 Tax=Mycoplasma mycoides group RepID=Y714_MYCCT  E=9e-23 s/c=0.56 id=24% cov=66%
-LDIVYEDNNILIVNKPNNLEMHSIYNLCLDDMVKSYLVDKKEydiylenSFVISHVHRLDKLTSGLVIYAKNKISSIILTNAFKTKdQINKYYYALTSYDWNLNDFLQVNGYINYNSNTQKADfslVEKNNYKYCQTEFKLVNKN---------------LILVKLITGKKHQIRSVLSFYNNPILNDFRYNGKKEN-------------------------------------------------------------------------
>UniRef50_D2L201(87-269:313) Pseudouridine synthase n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L201_9DELT  E=3e-22 s/c=0.59 id=27% cov=70%
-VPVLVQTGDFAAVSKPAGL--HSAAIAHGGGQSLDDLLPALFPDRAAIlLSRLDRLTSGIVAVALTPGAGTRYRDLEDAGQVAKDYLAVVHGVIADPFVVDFRLDTADRAKTRVRFKSEPDPLR-HTQVEPLDRLD-----------GLTLVRCRIAKGARHQIRAHLAGAGHPLVGDPVYGRGEGE----------RLHLHCAALA-----------------------------------------------------
>UniRef50_A1VAY5(174-368:400) Pseudouridine synthase n=3 Tax=Desulfovibrio vulgaris RepID=A1VAY5_DESVV  E=3e-20 s/c=0.52 id=25% cov=72%
----------LVAVYKPGGLHSAALAGGRAPNAENLL-------PALKLLNRLDGPTSGILMLAGDTAGERQWRKAEDEGGTRKTYLAVCTGRLE-RGTVVRAALDTARRTVTRVRPCDTDDRLRHTEVVPLAHFrlgdlanpiTDDSAGVPACDETVTLVCCRIRKGARHQIRAHMAHIGHPLLGDDVYAAPASPPPGRM-----PLFLHHSRITLP---------------------------------------------------
>UniRef50_C1E520(58-370:372) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1E520_9CHLO   E=4e-20 s/c=0.32 id=27% cov=92%
---VLYVDprARFFVVNKPAGMYVenvldfierymeevrraperHSERSKRAKTcsdgATSIREAFDSLakvGERFQLLHRLDRDTTGCLGIACDKETNRILSRAFQEGRVKKHYVAhcintkfaddfqkkwkdwevdepfedgsramtWPQRFCNFRLECHTGHGRSKHGLWRLYAKEDVGrelpggskVKEARTNlYRGFDSDSDSKRLAHLRELQSFPVVAEPITGRTHQIRMHCSQY-FPIVGDYKYGyDDTADDDVVQEEREKGYRLHSFSLELPikIPDGNgfRDTLVLAPPPSWWNE--EEWGTYDILMERF----------------
>UniRef50_B2S2A1(107-304:345) Putative uncharacterized protein n=2 Tax=Treponema pallidum RepID=B2S2A1_TREPS  E=2e-19 s/c=0.50 id=25% cov=68%
---VVFKTQDLLFFHKPAGLCVHgPRSLDAWVRGQGRAHVPPALSFRPGPLHRLDRGTEGLIAFSRSLRGAQWFSAALQQHTLRKFYL------------AITAAPARTAAAARTLVRPGE-----VTHVQTVLHSCDSALVLRV---------IVPVTGKKHQIRRYCAAQGFPLVGDRTYGGASQHGNARYT----RFFLLAWCVRFP---------------------------------------------------
>UniRef50_C1MVV0(139-354:539) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MVV0_9CHLO  E=2e-19 s/c=0.45 id=29% cov=69%
---VLTEDERVVIVDKPPGLPtlagVGPGVAGENNAVAVLRRLRASasasakrkreesddggggggggddDDAPLFAVNRIDKPVSGVWILAKgsrlSARARDALHKGAARGETRKTYVALVKGRVEVGGGGAGGGGFVVDAPLRKderglAVVGGDGAKPAATRVVPLAVVAVPSKGGGGEKEALTLAAVALEkSGRYHQIRAHLAHVGHPIVFDRDY-------------------------------------------------------------------------------
>UniRef50_Q5A0Y2(11-221:247) Pseudouridylate synthase PUS5 n=4 Tax=Candida RepID=PUS5_CANAL   E=6e-19 s/c=0.46 id=22% cov=67%
------------VVNKPSGMVC--DASHTNNIITALtneftKILPSVNSSQFRLVQRLDRFVTGGLVVARNKKWADKVRKSFFQEgtlRLTRRYVgliALDQIPESTQGTIDFPIQALEKDYRGKNKSRELFTYSAVTHYKLIpsARRTIKGVFPVFQQGPILPIILELETGRKNQIRDHiIQKFGVPLLNDDNFSDFKLN-------------------------------------------------------------------------
>UniRef50_C2D7I2(84-245:285) Pseudouridine synthase n=1 Tax=Atopobium vaginae DSM 15829 RepID=C2D7I2_9ACTN  E=7e-19 s/c=0.60 id=25% cov=62%
-------DHVYLLLNKPSQVLT--TMSDPFGFPCVASLVPCDDYPGLFPVGRLDSDTTGVLLFTTNGNMGNRLLH--PSHHVWKTYVALIEGKLTSSQMQKLSQGIMLEDGMTSPCFIRT-----ITQDEPCTHLDKNHSLFDDMRLNAasSLCELKIHEGRNHQVKRMLQEIGHPVI------------------------------------------------------------------------------------
>UniRef50_A5BEM4(4-129:208) Putative uncharacterized protein n=1 Tax=Vitis vinifera RepID=A5BEM4_VITVI  E=1e-18 s/c=0.76 id=34% cov=42%
-------------------------------------------------IHRLDRLVSGLLILARSASKADSFRQQIEAGMVQKQYIAKVTGVFPDDEVGNC------------CGNTPLKGKSACTKFTRIST-----------NGTHSIVLCEPITGRTHQIRVHLQYTGHPIANDMLY-------------------------------------------------------------------------------
>UniRef50_C8WGQ8(74-243:282) Pseudouridine synthase n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WGQ8_EGGLE  E=6e-18 s/c=0.55 id=28% cov=62%
-----------IMLHKPAGFVT--TMSDPQGRRTVAELVPTERYPGLFPIGRLDFDTTGLLLFSTDGELGNGLLH--PKHHVTKRYLACVEGRPTERDLALLRRGIELDDGPTQPADVRVVEGGAARHAERLleipaavppRSSKEYAAVCEGRATRRSIVRLGIREGRKRQVKRMLAAVGHPVL------------------------------------------------------------------------------------
>UniRef50_Q6P087(82-341:343) RNA pseudouridylate synthase domain-containing protein 3 n=35 Tax=Theria RepID=RUSD3_HUMAN  E=8e-18 s/c=0.36 id=21% cov=62%
----------LVTLNKPQGLPVTGKPGELTLFSVLPELSQSLGlrEQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHaRRAQRptaTYCAVTDGIPAASEGKIQAALKLEHIDGVNLTVPVkapsrkdilEGVKKTLSHFRVVAT-----------GSGCALVQLQPLTVFSSQLQVHMVLQLCPVLGDHMY-------------------------------------------------------------------------------
>UniRef50_B0TFD8(68-206:333) Pseudouridine synthase n=18 Tax=Bacteria RepID=B0TFD8_HELMI   E=2e-17 s/c=0.66 id=25% cov=53%
------------ALYKPRGVVT--TCKDPQGRQTVIGLL-SGVNERVYPVGRLDRDTEGLLLLTNDGQLAFRLTH--PRFGVEKTYRARLRGDVSAGALKALAEG-----------VQLEDGVTAPAQVRLLRR-----------EGDATWIEIKIHEGRKRQIRRMGDAIGHPVI------------------------------------------------------------------------------------
>UniRef50_Q6FS81(5-174:223) Pseudouridylate synthase PUS5 n=1 Tax=Candida glabrata RepID=PUS5_CANGA  E=1e-16 s/c=0.52 id=28% cov=57%
-LKVVYDGMHYMIVYKSAGVLSQPG-LASDSRPVLMSELRGLLSEtlDLYSVQRLDACVTGGTVVAKNKRAAMMFSRYLKQgggsgYGLTRRYLARINAQPVCDEGTIESPG-------------------MVTYYRRVRDDC---------------VVVELKTGKKHQIRKHLAlNLNCPIVNDTYYGG-----------------------------------------------------------------------------
>UniRef50_C1MJ36(166-476:483) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MJ36_9CHLO  E=2e-16 s/c=0.29 id=26% cov=68%
--------DAFVVVDKPAGVNVGFTVDNAKECVaqCVARALGDAFAENgsdssstdsstecsswgwadatpLIVTHRLDAATSGVLVLARDVEFARHFNDALRERKVQKTYACVSEARVPVGVMEHWTDPEDATRGPRRHVmrppregdtpweergggggetstsiaeeraekaaattskqkksqrqkkrerrlakaeefVHPDGRRRCVLRVLTCEEVKIPGEKAGDAPPRYeSTVE--LVTGRTHQIRAQFAASGAPLLGDVLYGGAR---------------------------------------------------------------------------
>UniRef50_B3GZS7(37-191:232) Pseudouridine synthase n=10 Tax=Pasteurellaceae RepID=B3GZS7_ACTP7   E=3e-16 s/c=0.57 id=25% cov=60%
-----FEDTVVVLFNKPFDVLTQFT--DEQGRQTLKDFI---PIPQIYPVGRLDRDSEGLLLLTNNGEIQHRLAN--PKFEKQKTYLAQVEGIPQAADLAKLEKGVELKDGLTKPAKAKAISAP---NYE----WQTAPKIRERKTIPTSWIELKIHEGKNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_UPI0001924EE0(45-150:153) PREDICTED: similar to predicted protein n=2 Tax=Eumetazoa RepID=UPI0001924EE0  E=5e-16 s/c=0.82 id=30% cov=38%
--PVIHEeiefiqnNEEVVVINKPASIPVHPCGRFRHNTIV-FILGKDYGLYNLHTIHRIDRLTSGVLMFAKTSKKARELEGLVRGRLVIKEYLARVIGDFPRTQVM----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8DKC4(144-433:463) Pseudouridine synthase n=1 Tax=Desulfovibrio vulgaris str. 'Miyazaki F' RepID=B8DKC4_DESVM  E=7e-16 s/c=0.30 id=28% cov=70%
--HVLAETDGLVALYKPGGLHSaavagsaapsveallptllgqpdmtaladHADPADLPGLTDLADpaaltDLAAPDASRPSPVaddttgfprllNRLDGPTSGILLAARAPQAAQRFHAAENSGQATKTYIALVHGVLAQPMKVRRGLDTANRATTRVLPQDTPDAlrHTMVTPLGIMQTTDIPDAAPCTPtlagdagqdsapasactthapgpactsGTPCTLVRCVIRKGARHQIRAHLAVLGHPIVGDTRYG------------------------------------------------------------------------------
>UniRef50_C1MNL7(209-524:548) Predicted protein n=1 Tax=Micromonas pusilla CCMP1545 RepID=C1MNL7_9CHLO  E=5e-15 s/c=0.27 id=27% cov=69%
---VVYEDEETLAVNKPHALPTQAHESNAAECVpgCVARALGFTGGvtdgdDALLVTHRLDASTSGVVVLGKTLGAVRAFNASIAgGKRVTKTYVALVENasnvrrrgvtvedattPPPPVPLGRFVHYMYPGPfgasalggrgarrsnarllRRRAPSASDGDAKPwrrcelvvrscARASPRDVAAWRalfaesvegnanweaargvddgsRDEPSRRAGDDAVYEVEIELVTGRTHQVRAQLAALGFPILGDTLY-------------------------------------------------------------------------------
>UniRef50_D0NJP5(65-425:458) RNA pseudouridylate synthase-like protein n=1 Tax=Phytophthora infestans T30-4 RepID=D0NJP5_PHYIN  E=7e-15 s/c=0.23 id=31% cov=75%
-LRVLSRDEHFVVLNKGPDVRM---DGAFDVTLEKALARDFPQVEKFRWIHQLDFATSGVLVVGVNKDATATGCRLFREKQVQKEYLAVVRGHLPfnpaesvdtaalpakactfsklglliqdmeemerlrnqqrgsraHQKTPGYPRGVRHGPNlftmeqaqllpeareltpaelaftKMTWHDLTKEEKGAYTEkakadkrrflkefseflnqekirlarkrkyesfdgedseeanepvayvfdapviephrstgvFRMLVGTETDTAAKQsttmcfvlghaiYKGEPVTKVLLRPLNGRRHQLRLHMAHHGFPIAGDVTYGSQEDE--------APRMMLHAWRI------------------------------------------------------
>UniRef50_Q65HX7(62-202:244) Pseudouridine synthase n=5 Tax=Firmicutes RepID=Q65HX7_BACLD   E=8e-15 s/c=0.59 id=22% cov=53%
-------------LYKPRGVIS--AVKDDKGRKVVTDFF-TEVEERIYPIGRLDYDTSGLLLLTNDGDFANKLMH--PKYEINKTYVAKLKGIPLKENLKKLERGVRL-----------EDGKTAPAKVKLLS---------LDKKKQTSIVQITIHEGRNRQVRRMFEAIGHEVL------------------------------------------------------------------------------------
>UniRef50_A6G735(88-235:300) Pseudouridine synthase n=2 Tax=Bacteria RepID=A6G735_9DELT   E=4e-14 s/c=0.55 id=24% cov=55%
------------VLNKPDGVVSSAAGSvDERGRPTVISLLH-GVSERLYPVGRLDFHSRGVLLLTNDGGLAEALTH--PRHGVVKTYHVKFQGKLTEEQEQLLRDGVELDDG-------------AITR-------PVAELFAFRETATNVWYQIGIREGLNRQIRRMGEAIGHPVL------------------------------------------------------------------------------------
>UniRef50_Q0AX41(58-198:239) Pseudouridine synthase n=1 Tax=Syntrophomonas wolfei subsp. wolfei str. Goettingen RepID=Q0AX41_SYNWW  E=1e-13 s/c=0.56 id=26% cov=52%
-----------LLLHKPAGYIS--SLADPQGRPRVIDLLSA-VNTRVFPVGRLDYDTEGLLLLSNDGEFSNLMTH--PRYLIPKKYEAWVQGLVKPDTIRQLEQG-----------VALEDGITAPARVRLLSSKK-----------GQSLLELEIHEGKKRQIKRMCLAVGH---------------------------------------------------------------------------------------
>UniRef50_B0S1L0(58-199:242) Pseudouridine synthase n=2 Tax=Finegoldia magna RepID=B0S1L0_FINM2   E=2e-13 s/c=0.55 id=22% cov=55%
------EDKIYIAINKPIGYAS--TVKDKFADKKVVDLIKS--DTRVYPVGRLDKDSHGLLILTNDGEFTYELTHPKFEHK--KIYEVLVKGKPNKTEIKQLKDGILLDGYKLK-----------KSKIEFIENVKND-----------TKYRVTIFEGRNRQIRRMFDFINHPVL------------------------------------------------------------------------------------
>UniRef50_C0D9T3(103-282:300) Pseudouridine synthase n=1 Tax=Clostridium asparagiforme DSM 15981 RepID=C0D9T3_9CLOT  E=2e-13 s/c=0.44 id=24% cov=52%
----------LLAVNKPKGVVCTASDKDKAPNIVDMIQY----PVRVYYVGRLDKDSEGLVLMTNQGDLVNKIMRSGNAH--EKEYQVVVDRPVTA-----EFLARMEKGVRLKE----------------LDRTTLPCKVRKTGDKRFSIV---LTQGLNRQIRRMCEACGCHV-------------------------------------------------------------------------------------
>UniRef50_Q24V73(75-217:257) Pseudouridine synthase n=3 Tax=Bacteria RepID=Q24V73_DESHY   E=3e-13 s/c=0.55 id=26% cov=52%
-------------LHKPTGYIT--SVTDPQGRKTVME-LMPKIPRRVYPVGRLDYDTSGLLLLTNDGDLAHRLMH--PSYGVEKTYRVEVGEKIPEQALKRLEKG-----------VLLEDGKTAPARIR-----------EVSPKGRGSLptYEITIHEGRNRQVRRMFKAVGFPL-------------------------------------------------------------------------------------
>UniRef50_A3YG85(4-152:242) Pseudouridine synthase n=2 Tax=Gammaproteobacteria RepID=A3YG85_9GAMM  E=1e-12 s/c=0.51 id=23% cov=58%
----------IIVFNKPFQVLSQFTTDEEKATLSSFI-----DKANFYPAGRLDYDSEGLLLLTDHGALQHLIAS--PQHKMPKTYLVQVEGELTKEAVEQLRVGVELKDGLTK----PAEAKIA-SDFEP---WPRHPPIRERKNIPTSWLELTITEGKNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_Q3KZ50(120-219:230) SJCHGC01105 protein (Fragment) n=1 Tax=Schistosoma japonicum RepID=Q3KZ50_SCHJA  E=2e-12 s/c=0.75 id=26% cov=36%
-LRVVHEEQGFVVINKHPELLI-NCTNPWVNCLTLQMQLFYNRPQYVNWklknmfhfVHRLDCPTSGLICIAYDTKVASMIRRAFEKREVTKYYLAIVRGYV----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1QUR9(62-210:257) Ribosomal large subunit pseudouridine synthase E n=26 Tax=Bacteria RepID=Q1QUR9_CHRSD  E=3e-12 s/c=0.50 id=21% cov=58%
----------LYLLHKPYQMLSQFT--DTRGRATLAEAI---DVPDIYPAGRLDYDSEGLLLLTGDGALAHRISH--PRHKQPKTYWVQVEGEPEPAALQALRQGVTLRDGPTRPAKVRRLESP--------DVAPRHPPVRHREAVPTAWLELTLSEGRNRQVRRMTAHVGHP--------------------------------------------------------------------------------------
>UniRef50_Q7RGT9(151-258:1254) RNA pseudouridylate synthase, putative (Fragment) n=2 Tax=Plasmodium (Vinckeia) RepID=Q7RGT9_PLAYO  E=1e-08 s/c=0.58 id=26% cov=20%
---------------------------------------------ECGLCHRIDLETSGSLIIAKTKDARDFLFDQFRKRNVYKEYILLCHGRIKKK-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7GZ55(62-216:250) Pseudouridine synthase n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7GZ55_9FIRM  E=1e-11 s/c=0.47 id=29% cov=30%
-----------IAMNKPCGYVC--TVSDELGRRTVYDLLTD-IDERLFTIGRLDKDSEGLILLTNDGDLAQKLLS--PKRKIEKNYEVVVRGVP----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9HX48(11-159:189) Ribosomal large subunit pseudouridine synthase E n=30 Tax=Proteobacteria RepID=RLUE_PSEAE  E=1e-11 s/c=0.49 id=24% cov=57%
----------LLLFNKPFDVLTQF--NDEQGRSTLKDFI---PVPGVYPAGRLDRDSEGLLLLTNDGRLQARIAD--PRHKLPKTYWVQVEGTPDEEQL-----------RRLREGVTLNDGPTLPAEARLLDEptlWERVPPVRFRKSVPTHWLELVIREGRNRQVRRMTAAVGLP--------------------------------------------------------------------------------------
>UniRef50_Q4Q7F2(1-390:453) Putative uncharacterized protein n=3 Tax=Leishmania RepID=Q4Q7F2_LEIMA  E=1e-11 s/c=0.19 id=28% cov=77%
----------MLVVNKPPGILMDGDESIYGRTVESLVCEHmkargifdetheqlqkeKKRKKQLKFVHQLDFGTSGVLCLAFTKDMAARLAHCFEMRLVRKYYVALLHGHLPSDtalledaassdqpgsafssdtkarrasfaawanacnkaweglgcvragcsasasggssansaggdevagfrhllqrpdktaweavglanskdaeegepvtvvhryrshrspasslitvapensapvpadavedliyrtllestttcsvVFVDLPVGYDLTDPEHlRMAVTAEQSRDAKTSLLVLKRTYLAAPPPAGGEVpqrgaiakdspsvtsyPVTLVLLAPHTGRRHQLRVHCRAIGFPIVGDTSYCADLPWctalplgssPSTWVTAGARRMYLHAWRLLLP---------------------------------------------------
>UniRef50_B8G2X0(66-200:567) Pseudouridine synthase n=3 Tax=Bacteria RepID=B8G2X0_CHLAD   E=1e-11 s/c=0.54 id=23% cov=52%
-----------IMLHKPAGVVS--TAEDPHGRPTVVDLV--DVPARVFPVGRLDLDSEGLILLTDDGELAYALTH--PSFEVEKEYRVLLDRALTPDAL-----------RSWRNGVLLEGEMTAPAWVELLETTPEGV-----------WVRIVLREGRKRQIRAVAKLLGY---------------------------------------------------------------------------------------
>UniRef50_Q8ZPZ1(41-190:221) Ribosomal large subunit pseudouridine synthase E n=30 Tax=Enterobacteriaceae RepID=RLUE_SALTY  E=2e-11 s/c=0.48 id=23% cov=58%
----------VVLFNKPYDVLPQFT--DEAGRRTLKDFIPVQG---VYAAGRLDRDSEGLLVLTNDGALQARLTQ--PGKRTGKIYYVQVEGIPDNAALQALRTGVTLNDGP-----TLPAGIEIVAEPDWLWPRTPPI--RERKNIPTSWLKVTLYEGRNRQVRRMTAHVGHP--------------------------------------------------------------------------------------
>UniRef50_A4BW35(132-269:305) Pseudouridine synthase n=3 Tax=Flavobacteriaceae RepID=A4BW35_9FLAO   E=2e-11 s/c=0.52 id=28% cov=28%
-----------ILLNKPKNYIT--TMDDDRGRKTVMDLISNATKERIYPVGRLDRNTTGLLLFTNDGELAKKLTH--PKHDVRKLYHA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6C4P7(84-222:352) Pseudouridine synthase n=1 Tax=Planctomyces maris DSM 8797 RepID=A6C4P7_9PLAN  E=2e-11 s/c=0.51 id=24% cov=53%
-------------LNKPSGFLC--TNNDPAGRRRVVDLFPND-GQRLFTVGRLDENSEGLILVTNDGELAQRLAH--PRYRVARTYHVQVVGNPPREKLDELRKGVRFKEGVFRV----------------------SGLKYLKKQGKSAFLELTLHEGQNREIRRMMARIGHKVI------------------------------------------------------------------------------------
>UniRef50_C8NA36(1-73:80) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Cardiobacterium hominis ATCC 15826 RepID=C8NA36_9GAMM  E=3e-11 s/c=0.98 id=24% cov=26%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAQHYPLVGDPLYglatpsGKGLPPEVRQTLLAFPRQALHATALTLSHPADDDEITFASPLPADMQTLLAAL--------------------------
>UniRef50_Q6FCZ3(3-152:264) Pseudouridine synthase n=2 Tax=Gammaproteobacteria RepID=Q6FCZ3_ACIAD  E=3e-11 s/c=0.47 id=22% cov=57%
----------IVVFNKPYDVLSQFREDSAHLTVSSFIA-----DPELRIAGRLDLDSEGLMFLTDHGGLNQYITH--PSNKKYKTYLVQVDGDITEDA---------LEKLRKGVELADGLTLPAQaTKVeEPEWLWERNPPVRFRASIPTSWVEISICEGRNRQVRRMTATVGFP--------------------------------------------------------------------------------------
>UniRef50_C6W5I1(4-158:201) Pseudouridine synthase n=1 Tax=Dyadobacter fermentans DSM 18053 RepID=C6W5I1_DYAFD  E=4e-11 s/c=0.46 id=16% cov=58%
-------------IYKPFNMLSQFSREGDHQTLAD---LGFTFAKDIYPVGRLDADSEGLLLLTNDNFLKTKLLEPRNRH--TRTYYVQVEGEVTDEACRQLSAGVSISiNGKQYKTLPAEIAKIAEPEL-----PERNPPIRFRKNIPTSWLSVTLREGKNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_Q87NB7(68-210:312) Ribosomal large subunit pseudouridine synthase B n=17 Tax=Bacteria RepID=RLUB_VIBPA  E=4e-11 s/c=0.49 id=28% cov=33%
----------VLAYYKPEGELC--TRHDPEGRRTVFDRLPKIRGSRWISVGRLDANTSGLLLFTTDGELANRLMH--PSRQVEREYLVRVFGEVTEQKV-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9KY92(69-206:282) Pseudouridine synthase n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9KY92_THERP  E=5e-11 s/c=0.51 id=20% cov=53%
-----------IVLHKPVGYIT--TTADEYGRKTVLDLVQ--VPERVVPVGRLDRDSSGLLLLTNDGDLIYRITH--PRYELEKEYEVLVDGFPPPEVEEALRRGVPVDGRPVR--------------IRRLEAIRVEPQG--------TVYRVVIHEGRNRIIRRVFERVGYPVL------------------------------------------------------------------------------------
>UniRef50_C8NZC3(68-212:246) Pseudouridine synthase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8NZC3_ERYRH  E=5e-11 s/c=0.49 id=23% cov=53%
------------ILNKPRGIVS--SANDDKDRESVVDLVPNDI--RVFPVGRLDRETTGALILTNDGDFAYYMTH--PKFDLSKIYRVSVRGRLSYEVTNSL--------------------KEGITIEGVEYKGVEISRVKYDAAKDKTQFSITLHEGKNRQIRKIFAHFGLPVL------------------------------------------------------------------------------------
>UniRef50_Q01SF5(66-199:249) Pseudouridine synthase n=3 Tax=Bacteria RepID=Q01SF5_SOLUE   E=6e-11 s/c=0.52 id=24% cov=52%
-----------IALNKPKGTVT--TVHDPEGRETVMDLLH-RVKERVYPVGRLDYHSEGLLLLTNDGELANSIMSA--ATHLEKTYVVKVTGTLTAEQE-----------EKFRTGVPLSGRRTLPAGLKLLSRAENP------------WYEVKLTEGRNNQIRMMFRHFG----------------------------------------------------------------------------------------
>UniRef50_UPI000196BAD7(59-202:247) hypothetical protein CATMIT_00510 n=1 Tax=Catenibacterium mitsuokai DSM 15897 RepID=UPI000196BAD7  E=9e-11 s/c=0.49 id=25% cov=20%
------EDKVYYLFYKPEKCVC--TMSDEHDRTCVADYFADS-NERVYPVGRLDYDTTGAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4CJ52(128-268:303) Pseudouridine synthase n=5 Tax=cellular organisms RepID=A4CJ52_9FLAO  E=9e-11 s/c=0.49 id=24% cov=53%
-----------VLLNKPRNFIT--TTRDEKGRRTVMELISRASNARLVPVGRLDRNTTGLLLFTNDGELAKKLTH--PKHGVRKIYHVELDKTFKSADLGKLREGLELEDGR-------------------IEVDEASYIDGASKKE----VGVELHSGRNRIVRRIFEHLGYQVV------------------------------------------------------------------------------------
>UniRef50_C6J9Y4(74-243:323) Pseudouridine synthase n=2 Tax=Clostridiales RepID=C6J9Y4_9FIRM   E=2e-10 s/c=0.40 id=21% cov=50%
----------LLLFNKPRGIVCSTKQQFDETTVTDYL----DYPLRVYPVGRLDKESQGLLLLTNEGDLVNKIMRAGNYH--EKEYFV----------TVNKPVDREFVRRMSKGVP-------------VLDTVTRPCRVVQTGECSF---RIILTQGLNRQIRRMCRYLG----------------------------------------------------------------------------------------
>UniRef50_C8PVP6(4-163:234) RNA pseudouridine synthase family protein n=1 Tax=Enhydrobacter aerosaccus SK60 RepID=C8PVP6_9GAMM  E=2e-10 s/c=0.43 id=19% cov=60%
----------LILFNKPYGVLSQFRSDDNNNFATLSDY---FTDKSLRVAGRLDATSEGLLLLTADGQVNKALTHppkANAGKQQGKTYWIQVEGDASDAQLQQLQTGVPLKDGItlPAEVVRLSEAQIAEHIWQ--------ASDKIAKRKVTTWLAITIFEGKNRQVRRMAAHVGLPCL------------------------------------------------------------------------------------
>UniRef50_B1X5I1(61-206:242) Pseudouridine synthase, Rsu n=1 Tax=Paulinella chromatophora RepID=B1X5I1_PAUCH  E=3e-10 s/c=0.47 id=25% cov=55%
-------DNHVtLLINKPTGVIS--SCQDPQGRPTILDLIPQSIlqNRKLHPIGRLDSNSRGALILTTDGSLTMNLSHPRYSH--DKAYKVWVEGRPSSSVIKIWQQGIFLDKKMTSRV-----------ELKILCKRVTS-----------TLLEIVMKEGRKRQIRRTATFLGHPVI------------------------------------------------------------------------------------
>UniRef50_C7PP04(341-476:516) Pseudouridine synthase n=1 Tax=Chitinophaga pinensis DSM 2588 RepID=C7PP04_CHIPD  E=4e-10 s/c=0.50 id=37% cov=28%
-----------ILLNKPKGYIT--TTDDPEGRKTVMELIQDatTEEQRVYPVGRLDRNTSGLLLLTNDGELAQKLAH--PKHNIKKIYH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9NGL0(62-201:238) rRNA pseudouridylate synthase n=1 Tax=Acholeplasma laidlawii PG-8A RepID=A9NGL0_ACHLI  E=1e-09 s/c=0.47 id=30% cov=27%
-------------LNKPTGYLSTTADIHKRRNI-LDLILKEDQNVRLFPIHKLEYDTSGLLLVTNDGELTKKLTSQSES--IQKEY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8BYZ7(446-540:571) Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BYZ7_THAPS  E=3e-09 s/c=0.68 id=42% cov=23%
---------------------------------------------------------------------------------------------------------------------------------------------------------LKPWTGRRHQLRVHLALVaGFPILGDVAYSKEETKQRV---MTCERMCLHAHMLSI--PLLGEE--------------------------------------------
>UniRef50_A9AXM1(63-197:728) Pseudouridine synthase n=3 Tax=Bacteria RepID=A9AXM1_HERA2   E=2e-09 s/c=0.48 id=22% cov=52%
---------HYVLLHKPSSVMT--TLHDPEGRQTVADLVKSHN--RLFPVGRLDYDSEGLLLLTDDGDLTFRLTH--PSFEVEKEYQALLNQTPSVEQLRE-----------WRNGVELDDGKTAPAWIELL-----------NETADGTWVRVVIHEGRNRQIRRVAEALG----------------------------------------------------------------------------------------
>UniRef50_Q1D9N8(86-225:268) Pseudouridine synthase n=4 Tax=Cystobacterineae RepID=Q1D9N8_MYXXD   E=2e-09 s/c=0.47 id=25% cov=53%
----------VLAFHKPAGLLSSTERQHRTGTVFEALLPQlppELAGYTWHAVGRLDVDSTGLLLFTNDDKLVAHATS--PDAHLPKRYVA---------TVFSTASDERVEPLRRGMTLDDGPARPAKVNVRDEHT-----------------VEVTLTEGRHHQVKRMLGAVGLPV-------------------------------------------------------------------------------------
>UniRef50_B6KCA6(17-122:231) Putative uncharacterized protein n=3 Tax=Toxoplasma gondii RepID=B6KCA6_TOXGO  E=2e-09 s/c=0.62 id=33% cov=22%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------RLHAASLGHSVIGDPTYGPEVHRR--RHHRCDKPLMLHCWILKIAPPYAQEEVCVEAP--------------------------------------
>UniRef50_Q8X4Q8(69-204:290) Ribosomal large subunit pseudouridine synthase B n=117 Tax=Bacteria RepID=RLUB_ECO57  E=2e-09 s/c=0.48 id=24% cov=34%
----------VLAYYKPEGELC--TRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMH--PSREVEREYAVRVFGQVDDAKLRDL--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6VS09(12-165:225) Pseudouridine synthase n=1 Tax=Dyadobacter fermentans DSM 18053 RepID=C6VS09_DYAFD  E=3e-09 s/c=0.42 id=15% cov=55%
------------IINKPPNMVSQFVSSHD---VRLLGELDFDFPEGTHAVGRLDSMSEGLLILTTNKKVTNLLFLGEVPH--TRTYWVNVGHIVPPETVQLLRTGIPIRVKGGGYYT------TAPCEVEVIERPAilPWHQSEGQPGVPNTWLSITLTEGKYHQVR-----------------------------------------------------------------------------------------------
>UniRef50_B5INL2(16-167:243) Ribosomal large subunit pseudouridine synthase E n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5INL2_9CHRO  E=7e-09 s/c=0.42 id=22% cov=58%
-----------LLFHKPYGVLSQFTPEPGSRWRCLADFIA---VPGVYAAGRLDADSEGLLLLTANGRLQQRLTDPAFGHW--RTYWVQVEGEAGQRPEALQQL-------RQGVVIQGRLTRPAL--VRCLsdpKLPERDPPIRQRATIPVSWLELQLQEGRNRQVRRMTARVGLP--------------------------------------------------------------------------------------
>UniRef50_C1A8K5(63-195:237) Pseudouridine synthase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A8K5_GEMAT  E=7e-09 s/c=0.48 id=29% cov=51%
-----------IVLHKPA--AVMTTRKDPEGRATVFDLV--DDAPGLVYVGRLDFMTEGVLLLTTDGTAAHVLTH--PSHEVERTYVATVRG----DAVTAAREARRGVKLDDGLVVPSE-----VTAY--------------PLGERRWAFELTITEGRTHEVRRICDALG----------------------------------------------------------------------------------------
>UniRef50_B9ZS86(53-205:318) Pseudouridine synthase n=2 Tax=Chromatiales RepID=B9ZS86_9GAMM   E=8e-09 s/c=0.41 id=27% cov=32%
-----------LVYHKPVGEIC--SRSDPEGRKPVFASLPRLKGQRWVAVGRLDLNTSGLLLFTTDGELANRLMH--PSHSLEREYAVRVLGEVPDD-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3LZQ0(15-246:265) Pseudouridylate synthase (Fragment) n=1 Tax=Pichia stipitis RepID=A3LZQ0_PICST  E=2e-08 s/c=0.27 id=20% cov=65%
-----------VVVNKPSGIQCSGFKNYAHHLLpqltkkfKALHPDRTLNASQFKLVHRLDKYVTGGLVVARDRKWAMKSSKSLsskgnSPDSIIRRYVGLLPIPEDDslkSGWITYDIQAPQKDYKGSTETRKVLSYKALTIFQILDELKLQPTKTQlsmypkiYSGKCIVPIILQLQTGRKNQLRDHtLQSFNTTLLNDD---------------------------------------------------------------------------------
>UniRef50_C9RK28(65-242:243) Pseudouridine synthase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RK28_FIBSS  E=2e-08 s/c=0.35 id=21% cov=55%
----------VIMFHKPAGCVC--TKDDPQGRRTVYDYLPPGY-HNFKYVGRLDLQSRGLLLFTDDGELLYRLTH--PSFEVPRSYYVWTTRPLSESAAQRLVDGVDIRDP------EDPDAQE-----------EIAFATDVYLENGFA--ELVLIEGKNREIRRMMRAIGYEI-------------------------------------------------------------------------------------
>UniRef50_C8WBY9(332-466:509) Pseudouridine synthase n=3 Tax=Zymomonas mobilis RepID=C8WBY9_ZYMMN   E=3e-08 s/c=0.45 id=27% cov=51%
--------------HKATGLLT--TERDPEGRKTIYDRLPADL-PRVMPVGRLDMNTEGLLLLTTDGGFKRMLE--LPATHIERCYRARVFGDVSQDQLEELIEGVTIDGI----------------HYGSID------ANLERRTGRNGWVEMKLHEGRNREVRRVLGYLG----------------------------------------------------------------------------------------
>UniRef50_C6XLQ6(73-210:247) Pseudouridine synthase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XLQ6_HIRBI  E=4e-08 s/c=0.44 id=26% cov=52%
-----------VMLNKPAGVTC---SRKDSGTLitELFPSRWDKRDPLLSPIGRLDKETSGLLLLTDDGQLNHRVSS--PKTQTPKRYHVI--------------LDRDLNGDEDSIFAAGELMLESET--KPLLPAELSALGKREAI-------LTLHEGRYHQVRRMFAAVG----------------------------------------------------------------------------------------
>UniRef50_Q21EB0(66-198:249) Pseudouridine synthase n=14 Tax=Gammaproteobacteria RepID=Q21EB0_SACD2  E=6e-08 s/c=0.45 id=24% cov=27%
-----------IMLNKPAG-RVSATKDSTHPTVVG--CLPQQLQANIHIVGRLDFNSTGLMLLTNNGAWSRHLTS--PENKVNKIY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1SPF0(59-193:229) Pseudouridine synthase n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SPF0_9BACT  E=6e-08 s/c=0.45 id=19% cov=30%
------EDYFYWAFYKPKSVLTAYGDGHGKDTLEIYPFLRE---KKPAYSGRLDYDSEGLIIFSNDGDFIRRL--QRAEEKVEKEYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8KTF1(149-291:311) Pseudouridine synthase n=1 Tax=gamma proteobacterium NOR51-B RepID=B8KTF1_9GAMM  E=1e-07 s/c=0.41 id=22% cov=24%
---------HYIMLNKPSGVVC--ATRDARHR-TVIDILDLPFQHTLHIVGRLDIQSTGLVLLTNDGQWSRRLS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0SGV7(66-204:247) Pseudouridylate synthase n=2 Tax=Leptospira biflexa serovar Patoc RepID=B0SGV7_LEPBA  E=3e-07 s/c=0.42 id=20% cov=54%
----------IIAFNKPPGFLTSHEDKHHENTIFTLL---PESFQKYNYAGRLDLDSRGLILLSIDGNFIQKVTH--PKNKIDKEYIISLKQPVSWKKIAEEFMLG-----------VREGGET----LRALAVKPANVFPEKTPPGFTSYLSIVLKEGKKRQIRRMCK-------------------------------------------------------------------------------------------
>UniRef50_UPI00016B2405(75-233:237) pseudouridine synthase n=6 Tax=candidate division TM7 RepID=UPI00016B2405  E=1e-06 s/c=0.35 id=15% cov=55%
-----------LMLNKPINYVC--SRKQQGKTPTIYSLLPDKF-HNLKPVGRLDANSSGLLLLTNDGDFAFRMTH--PKFKKNKQYnVTLDKELAPLHQQMIADFGIQLNDGLSKLGLSRQSNQDRHNWIVTMSEGRNRQIRRTFAALGYTVIKLH----RTH--------------------------------------------------------------------------------------------------
>UniRef50_B4RA72(216-350:521) Pseudouridine synthase n=4 Tax=Caulobacteraceae RepID=B4RA72_PHEZH   E=3e-06 s/c=0.40 id=23% cov=30%
--------------HKPVGLVT--THKDPQGRPTVFEALPEGL-PRLISVGRLDLNSEGLLLLTNDGGLARALE--LPATGVVRRYRARAHGRITQE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9NFY3(57-198:236) Pseudouridine synthase n=1 Tax=Acholeplasma laidlawii PG-8A RepID=A9NFY3_ACHLI  E=5e-06 s/c=0.38 id=21% cov=20%
------EEKFYILLNKPVGIVSTTNTAISGNMITFM-----NFKEKIFPVGRLDKDSHGLILL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3Z8C8(72-210:249) Pseudouridine synthase n=5 Tax=Dehalococcoides RepID=Q3Z8C8_DEHE1   E=5e-06 s/c=0.39 id=29% cov=28%
-----------LMLNKPPEIVS--TTSDELGRKTVMDLLhRRYEGAGLFPVGRLDETTTGLLLLTNDGELTNRLTH--PSYEIEKEYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4XQU4(7-254:368) Putative uncharacterized protein n=2 Tax=Plasmodium (Vinckeia) RepID=Q4XQU4_PLACH  E=1e-05 s/c=0.21 id=13% cov=23%
------------VIEKEYGVSTFGRSEKKKSIIKSLQLLNNENAHNFEIVY-LHSTVGGCLLICKNQFIKKHL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6GU42(35-177:214) Pseudouridine synthase n=1 Tax=Limnobacter sp. MED105 RepID=A6GU42_9BURK  E=1e-05 s/c=0.37 id=23% cov=54%
-----------VLMHKPAGY---ETSHLPSHNPSVFDLLPKHYIKRgLQAAGRLDVDTTGLLLFSDDGQFIHRLIsgKVGTKQEIEKIYEVTGARPFSDLQLQRLLEGVDLDDEPEIIY----------------ASRATLLADGR--------LELGITTGKYHQVKRMVAAVGNHVDG-----------------------------------------------------------------------------------
>UniRef50_A0CY18(99-276:337) Chromosome undetermined scaffold_30, whole genome shotgun sequence n=2 Tax=Paramecium tetraurelia RepID=A0CY18_PARTE  E=2e-05 s/c=0.29 id=21% cov=32%
------------IFYKPVGMICSHNDPFKRPSFYDFAKLRLKTDQHIISVGRLDFNSEGLIVVTNDGELAR--CMELPETKLQRIYRVRVYGTFTEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6XI22(75-219:315) RNA-binding S4 domain protein n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XI22_HIRBI  E=0.0001 s/c=0.34 id=19% cov=20%
-----------VILNKPIDYVSaHPNEGEvpavrllTKANLSGQSETIPDRDTRLAPVGRLDKDSRGLLIL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0MUX7(106-260:293) Ribosomal large subunit pseudouridine synthase F, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0MUX7_PHYIN  E=0.0005 s/c=0.31 id=23% cov=28%
-----------LVLNKPLGYVS--SQPELNKTPAVRLLTFENECQELSrvkprqnvepvalwkmaVCGRLDVNSTGLLLFTQDGTVAKKLLD--PKGGIEKEYL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C5SKU3(111-246:489) Pseudouridine synthase n=2 Tax=Asticcacaulis excentricus CB 48 RepID=C5SKU3_9CAUL  E=0.0009 s/c=0.34 id=26% cov=22%
--------------HKPVGLMT--THQDPQGRPTVFNSLPQEL-PRVISVGRLDINSEGLLLLTNDGELARAL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9Y836(80-300:307) Pseudouridine synthase n=3 Tax=Firmicutes RepID=B9Y836_9FIRM   E=1e-64 s/c=1.12 id=32% cov=83%
-LNVVYEDHDVIVINKPKGLVVHPGPGNPDHTLVNGLLWHCHdlsginGVLRPGIVHRIDKDTSGLIVACKNDNAHQSLAKQLAEKTAGRQYYALVHGVINHEYGTIDAPIGRDEKDRQKMAVTEKNSRPAITHFKVVERFD-----------NYTLVSCRLETGRTHQIRVHMQYIGFPIVGDPKY-------SLRKTLPTQGQMLHAYQLSFTHPSTGERMTFEAPLPPEFEALLTQL--------------------------
>UniRef50_Q8DBG5(1-240:245) tRNA pseudouridine synthase C n=54 Tax=Gammaproteobacteria RepID=TRUC_VIBVU  E=3e-62 s/c=1.00 id=59% cov=93%
MLEIVYQDEYFVAVNKPAGMLVHRSWLDKHETQFVMQTLRDQIGQHVFPLHRLDRPTSGVLVFALSSEVASQVMPMFAGQEMSKTYHAIVRGWIEEEGELDYALKVELDKIADKFASQEKEAQDAITLYKPLAKVEVPYSTSKFPTTRYGLMELKPKTGRKHQLRRHMAHLRHPIVGDTTHGDGKHNKLFREEFDAPRLLLHASELRFVHPYTQQEVVIRAEVDKVWQQLFERFEWPSTL--------------------
>UniRef50_D2L0S2(91-337:558) Pseudouridine synthase, RluA family n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L0S2_9DELT  E=4e-62 s/c=0.97 id=33% cov=92%
-LRVLYADKELAVLDKPPGLTVHPAPGLPEGTLVNRLLHHFPGlremaGERPGIVHRLDKDTSGLLMVALTEPVRLALAADFAARQVHKTYLALVHGRPDGKGGDIRLPIGRDPKYRTKMAVPHKGGRPAHSRWRPVWTA---------PDGTASLLEVTIFTGRTHQIRVHMAAIGHPIIGDAVYGPHQHaawkRRGGAIARLASRQMLHAWKLSFTHPVLKEPRSFTCPPPPDF--------WRLLLLLGRRCQRIGVVGMPG----
>UniRef50_C6XFD0(90-338:340) Pseudouridine synthase n=1 Tax=Candidatus Liberibacter asiaticus str. psy62 RepID=C6XFD0_LIBAP  E=7e-62 s/c=0.96 id=25% cov=88%
-LDILYEDDDIIVINKPAGLVVHPAPGNWTGTLVNALLYHCHNNlssingvKRPGIVHRLDKDTTGVMVVAKNDLAHQKLSEQFvdhgKSTRLKRAYYAMVWGIPlPDSGIINAPLGRCKSNRLRRAVKgiDDKTADSAITHYQTIE------IYNKNSNFAVSLLKCHLETGRTHQIRVHMAHKGNPLIGDPLYGKGFKTKANIVNNNAKsailslaRQALHAHSLSFSHPRNNQDMDFQVPIPEDMLTVIRKLN-------------------------
>UniRef50_A9IQ66(81-330:334) Pseudouridine synthase n=5 Tax=Bacteria RepID=A9IQ66_BART1   E=5e-61 s/c=0.94 id=30% cov=88%
-LDILYEDDHVIVINKPAGLVVHPGNGNWTGTLVNALIYHCGNSlsgiggvKRPGVVHRLDKNTSGVMVVAKNDLAHKSLSAQFSDHGrtcaLDRRYHALIWGTPHRNVWTIDASLGRSPHNRTKQAVVHkqtPHARHAVTHFSLLEKY----GTHADSTSFASLLECRLETGRTHQIRVHMAHIGHPLIGDTVYGNAFKTKSNTLNPTLKnaidqfnRHALHAASLTFEHPSSGKVISFSAPLPQDMAQLIKHL--------------------------
>UniRef50_A1URK8(80-329:336) Pseudouridine synthase n=2 Tax=Bartonella RepID=A1URK8_BARBK   E=4e-60 s/c=0.93 id=28% cov=88%
-LHILFEDDHIIVVNKPAGLVVHPGHGNWTGTLVNALIYHCGDSlsgiggvRRPGIVHRLDKNTSGVIVVAKNDLAHKGLSAQFSDHGrtgvLDRRYHALIWGSPNRNIGVITASLGRARYDRTKQAVIHSHniyARHAVTHFSVIEKYQTCADKIPFA----SLLECRLETGRTHQIRVHMAHIGHPLVGDTVYGNAFKTKSNRFDstikeaiDLFNRQALHAASLTFEHPAKGNIMSFSAPLPQDMAELINHF--------------------------
>UniRef50_B6AN83(95-329:340) Pseudouridine synthase n=2 Tax=Leptospirillum RepID=B6AN83_9BACT   E=1e-59 s/c=0.99 id=33% cov=84%
-LEILYEDDDLIVISKPPGLVVHPAPGHASGTLVNGLLFHFQsqgdeqkkgepeeeeeaeRPLRAGLVHRLDQDTSGVMVVGKSETVVLDLMNQFKDRSVSKKYLALVKGILPKKRGEINAPIGRSTHDRKKFAV-RQDGKPSLTRYRVLETYHE----------NYSLLEVTLLTGRTHQIRVHFRHLGFPLLGDAVYGSK-----GMENRNFPRQMLHAWKLAFQHPRSAAKMEFEAPLPPDFVSAMKRL--------------------------
>UniRef50_B9JRD0(90-338:342) Pseudouridine synthase n=1 Tax=Agrobacterium vitis S4 RepID=B9JRD0_AGRVS  E=4e-59 s/c=0.92 id=31% cov=88%
-LTVLYEDKDLIVLSKPAGLVVHPGAGNWTGTLVNALIHHCGDSlsgiggvKRPGIVHRLDKETSGVMVVAKNDIAHRHLADQFADHGrsgpLERAYQALVWGRPRGlRGTIDAALGRAGDRTKRTVKREDtDDAREAITHYQVMERY----GEKPDATCLASLVECRLETGRTHQIRVHMAHIGHPLIGDPEYGaafktkaNLLPDAAKAIVTNFHRQALHAYLLAFEHPTTGDVMHFAAPIPDDMETIIRAL--------------------------
>UniRef50_C4XSN0(93-339:554) Ribosomal large subunit pseudouridine synthase D/dephospho-CoA kinase n=1 Tax=Desulfovibrio magneticus RS-1 RepID=C4XSN0_DESMR  E=8e-59 s/c=0.93 id=32% cov=92%
-LKLLYLDGDVLVLNKPAGLTIHPASSQPDGTLVNRLLHHFPDmramaGDRPGIVHRLDKDTSGLLLVAQTESARLALAADFAERRVAKTYLALVHGRPERSDGVIELPVGRDPKHPTKMAVVAKGGREAKSSWKLAWTA---------PDGTASLLEVAIATGRTHQIRVHMAAMGHPIVGDAVYGARQHSdwtrRGGAMARLAKRQMLHAWKLAFSHPGTGEELSFCQPPPADF--------WRLLLMLGRRCQRVGLVGMPG----
>UniRef50_C4FWV7(81-308:309) Pseudouridine synthase n=2 Tax=Firmicutes RepID=C4FWV7_9FIRM   E=9e-58 s/c=0.99 id=28% cov=85%
-LDIIYEDEDILVINKPAGLVVHPSKGHLKGTLVNGLLHYLNGNLstgsdfyRPGIVHRIDKDTSGLLVVAKHNAAHQALADQLLNHDMRRSYIALVHGQVKAPQGTIEAPLQRDPANRLRWTVAKE-GKYALTRFQVMENFE-----------NATLLDLELETGRTHQIRVHLEFIGHPLVGDPVYRKGLDHIKGSLVHDMTGQLLHAYALKLQHPRSGEWLEFKAPLPRRFEEALDQL--------------------------
>UniRef50_D0KVM5(81-309:340) Pseudouridine synthase n=11 Tax=Proteobacteria RepID=D0KVM5_HALNC   E=4e-57 s/c=0.98 id=29% cov=85%
-LDIIYEDDAIIVLNKSPDIVVHPAAGNPDGTLVNALLFHDPslvSVPRAGVVHRLDKQTSGVMVVAKTLAAHKILVENLAARKIRREYDTVVMGHVVAGGTVDAPIGRHPRDRQRQAVT--ATGKRAVTHYRVLQHY-----------GEQTWLRVQLETGRTHQIRVHMAHIRHPVIGDPVYGGRPRIPPRASTALIDvlrhfeRQALHARYLTLAHPVTGTQMRFEAPMPDDMRELIALL--------------------------
>UniRef50_Q49WX8(81-300:305) Pseudouridine synthase n=1 Tax=Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 RepID=Q49WX8_STAS1  E=2e-56 s/c=1.00 id=29% cov=82%
-LDIYYEDDDVAIVYKPKGMVVHPSAGHYTGTLVNGLMYQMKnlsginGEIRPGIVHRIDKDTSGLLMVAKNDVAHRSLVDQLVNKTVTRKYVALVHGKIPHdYGTVDAPIGRNKNDRQSMDVVDD--GKEAVTHFNVLEHF-----------NKYTLIECQLETGRTHQIRVHMKYIGYPLVGDPKYGPKK-------TLDIGGQALHAGIIGFEHPVTHEYIEKSTALPEDFEQLLSEL--------------------------
>UniRef50_C8S0A2(99-353:356) Pseudouridine synthase n=1 Tax=Rhodobacter sp. SW2 RepID=C8S0A2_9RHOB  E=3e-56 s/c=0.86 id=29% cov=85%
-LTVVWEDADLIVVDKPVGMVVHPAPGSYTGTLVNALLHHCgdtlsgvGGAKRPGIVHRIDKDTSGLLVVAKTDRAHHGLAAQFEAHSVTRHYIALVHGAPnaadprlrgirgvsfePGGIVCIATNLARHKTDRQRQAVLFDSGRHAVTRVRVLESYGTPPV--------AALVECWLETGRTHQIRVHMSHAGHALLGDQTYGGRRKVAPKAvgeavaqAANDFPRQALHAASLGFVHPVSGEELLFTSPLPADMAAL------------------------------
>UniRef50_A5GW76(88-316:316) Pseudouridine synthase n=1 Tax=Synechococcus sp. RCC307 RepID=A5GW76_SYNR3  E=4e-56 s/c=0.96 id=29% cov=83%
-LDVLFEDEHLIVINKPAGLTVHPAPGNKDGTLVNGLLHHCPDLPgisgklRPGIVHRLDKDTTGCIVIAKSQQALVKLQVQIQKRVASREYLAVVHGVPAgESGTIVGAIGRHPVDRKKYAVVSSDNGRYACTHWSLQERL-----------GDYSLLRFKLDTGRTHQIRVHCAHRNHPVVGDPTYSRCRKLP-----IELPGQALHAVQLGLDHPITGERMVFEAPLPEVLEKLLA----------------------------
>UniRef50_A9NGF1(76-297:297) Pseudouridine synthase n=1 Tax=Acholeplasma laidlawii PG-8A RepID=A9NGF1_ACHLI  E=4e-55 s/c=0.98 id=31% cov=83%
-LNIVYEDDDIMVINKPKGLVVHPSETFSETTLVSGLLHhtdtlstHNDDPLRPGILHRIDKDTSGLILVAKTNEAHKILAQDLKSHDIKREYIALVEGVLDHNKGVIDAPIARHPKIRTKMAVV-ATGKPAITHFEVMRTFR-----------DHTLLHCKLETGRTHQIRVHLAYIKHPVTGDPLYGTK-------AKILKDGQLLHAFRLEFVHPITKKVMMLEAPLPPEFESYLVTLG-------------------------
>UniRef50_Q14NK8(81-306:306) Probable pseudouridine synthase d protein n=1 Tax=Spiroplasma citri RepID=Q14NK8_SPICI  E=2e-53 s/c=0.93 id=31% cov=85%
-LTILYEDSYLMVIDKPNNLVVHPAPGHQNDTLVNALLARgvqwstASGEQRPGIVHRIDRQTTGTLIIAKNDVVHHQLQQQIQTKQLQRRYLALVHGQIIENRAKIDAPIGRDPNNRKKMVVTAKNSKKALTNIVVIERF-----------NDYTYIECELESGRTHQIRAHLKYINHPIVGDPLYGTVADKKESF------GQYLHAYQLRFIHPVTKESLTITAALPQEFEQRLAILRAKG----------------------
>UniRef50_Q9KQH0(97-312:315) Ribosomal large subunit pseudouridine synthase C n=59 Tax=Proteobacteria RepID=RLUC_VIBCH  E=4e-53 s/c=0.97 id=36% cov=83%
---IVYEDDHLLILNKPSGTAVHGGSGLHFGAIEALRALRPQ-ARFLELVHRIDRDTSGILLVAKKRSALRHLQAQFREKTVQKYYYALVMGHWDaECKVVNAPLLKNEVNS---IVRVNPNGKPSETRFRILEKF-----------AEATLVQASPVTGRTHQIRVHTQYMGHPIAWDDRYGDRRFDAYTAQ-FGIERLFLHAANIQFVHPASEKKLEIHAPLEAHLEQALTK---------------------------
>UniRef50_C8P3R0(83-303:308) Pseudouridine synthase n=1 Tax=Erysipelothrix rhusiopathiae ATCC 19414 RepID=C8P3R0_ERYRH  E=4e-53 s/c=0.95 id=28% cov=83%
-LDIVYEDDAILVVNKPKGLIVHPSPSTLNQpTLVHGLLAHTtqlsdlNGELRPGIVHRIDKDTTGLLVVAKTNEAHEILVEDLKQRLISREYVAIVHHQFKHQSATVDAPIGRDPKNRQRMAVTDQNSKQAVTHFYLAERF-----------NDFSVLRCKLDTGRTHQIRVHAQYIKHPIVGDQTYSYKNTWET-------NGQCLHAQKLTLTHPVSKEVMTFEAELPQTMKDVIEE---------------------------
>UniRef50_UPI0001C42CC7(105-320:322) hypothetical protein BpOF4_01845 n=1 Tax=Bacillus pseudofirmus OF4 RepID=UPI0001C42CC7  E=6e-53 s/c=0.97 id=30% cov=82%
-LDIHYEDDHLLVINKPQGMPTIPSREHPSRTLANAvmgYYESHHIPFTFHAVNRLDRDTSGLLVVAKHGLAHDQLSKGQRAGKLKRYYLALAEGFVqPREGTIHAPIKRRPSSIIERMVAAD--GQEAITHYKVI-----------NDNQAYSEVEINLETGRTHQIRVHFAHLGHPLLGDDLYGGSIE--------LLARQALHCQRVELIHPFTGKHLHFSAPLPKDLIEVKDKL--------------------------
>UniRef50_B8CWB7(93-309:310) Pseudouridine synthase n=1 Tax=Halothermothrix orenii H 168 RepID=B8CWB7_HALOH  E=9e-53 s/c=0.96 id=29% cov=83%
-LDIIYEDRHLLVINKPANMLVHPTPVEKSNTIVNgvLYHMRNQGNYNLvRPIHRLDRNTTGLLLIAKNQYAHNYITHQFQNNNIHREYLAFVHGNVEFKKESINAPIGKTRDSLIKRKVDHTLGKRAVTHIKVVK-----------PGGLISLIRVKLETGRTHQIRVHLSHLGHPLLGDTLYGG--------EDILIKRPALHSYKVTCCLPFKHKEVTFKAPLPVDMEKLKKQL--------------------------
>UniRef50_Q0F3G2(88-320:325) Possible pseudouridine synthase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F3G2_9PROT  E=1e-52 s/c=0.89 id=28% cov=83%
-LDILFEDEHLIVLNKPAGIVVHPSHGHDHGTLVHALLHHCKtlpginGVERPGIVHRLDKDTSGSLVIAKSEVVHQRLSEMFAEHNLNRQYIAWCRGVPSWRVKCIELPIGRHPHQRQKMAVTD-SGRESITDAAV-----------EHIFGPFSQMRLTLHTGRTHQIRVHMAHENLPVLGDPVYarsyhpGREIPEPARHAIATLSRQALHAELLEFDHPISGEPMSFRAPLPEDL---------------------------------
>UniRef50_Q1Q689(91-330:335) Similar to ribosomal large subunit pseudouridine synthase D n=1 Tax=Candidatus Kuenenia stuttgartiensis RepID=Q1Q689_9BACT  E=1e-52 s/c=0.87 id=27% cov=83%
-LNIIYEDDYLMLINKPYDMVVHPAGGHPSGTLVNAVtfycqnLSQINGPLKAGIVHRLDRDTSGVMLVIKSDAVHSHIAMQFEKRLVKKEYFAVVEGEVAFDSNEINMPIGRHRVDRQKMAVRRDTGKNATSVYEVIERFR-----------GYTLVKIMPKTGRTHQIRVHMQAIGHPVVADEMYSKYNacfrsdllgKERAPDEGSIIERQALHAHRIEFFHPILNKQMAFQVDMAED----------------------------------
>UniRef50_A5IZB6(76-291:305) Pseudouridine synthase n=4 Tax=Mycoplasma RepID=A5IZB6_MYCAP   E=2e-52 s/c=0.96 id=30% cov=81%
-LDIRYEDEYLLILNKPSGLVVHPAPGHLNDTLVNALMYHFKNNlsdanglLRLGIVHRIDKDTSGLLIIAKDNETHNELAKMLKNHQIKRTYLAICEGILPNKTTKINLPIQRDTKNR-KLMSIHKDGKSSVTYVHMLKSF-------YIDNKPYSLVKCELETGRTHQIRVHLAYIKHPVYGDSIYGKSVDEFN---------QRLHAYKLSFMHPVINKLIEVYSDIPKEF---------------------------------
>UniRef50_D0MK65(3-214:235) Pseudouridine synthase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MK65_RHOM4  E=3e-52 s/c=0.98 id=34% cov=82%
-LPILYEDDDLLAVHKPEGLAAIPER--DPSRPSARRLLEAARGERLWVVHRLDKEASGVLLFARNAEAHRYMNTLFEQRQVRKVYRALVHGRLEPGQGQIRAPIRMYGSG--RMGVDPERGKPSETRYRVLEYLDEA----------YSLIEALPLTGRRHQIRVHCYHIGHPIVGDPRYGDRSVQQRY------PRLMLHALSIRFRHP-NGQELEIVAPVPESFQQVLDAL--------------------------
>UniRef50_C6LL16(85-296:313) Pseudouridine synthase n=3 Tax=Clostridiales RepID=C6LL16_9FIRM   E=1e-51 s/c=0.97 id=31% cov=78%
-LDIVYEDEDLLVIDKPADMPVHPSIHNFDNTLANGLAYYYESRGEAFVyrcITRLDRDTTGLLLVAKNMLSGAFLAEMGKRREIHREYLAIVTGKTEAEGTVDAPIARVEGSVLER-CVDFQRGERAVTHYRTLEYRD-----------GYSLVRLKLETGRTHQIRVHMKYIGHPLTGDFLYNP--------DYRLMDHQALHSHYLAFRHPITGERMEFTSQPP------------------------------------
>UniRef50_C7GZW0(94-312:318) Pseudouridine synthase n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7GZW0_9FIRM  E=1e-51 s/c=0.94 id=25% cov=82%
-IEInaVYEDEHLLVIDKPAGIVVHPTHGYEENTIAHALIHYMdtvGEEFKIRFINRLDMDTTGLLMIAKNQFIQNAVVSEMKRGNVEKRYLAVVHGLPCNREGIIDAPIKAVEGEPRRQVM--EGGKPSITEYKVV---------GVSDELNVSFLDVRLHTGRTHQIRVHLKHIGCPILGDEFYGGKES---------ADRQLLHSRYLRFTHPVSKKIVELTANLPDDIASILTH---------------------------
>UniRef50_A9B3Z2(3-239:560) Pseudouridine synthase n=1 Tax=Herpetosiphon aurantiacus ATCC 23779 RepID=A9B3Z2_HERA2  E=2e-51 s/c=0.86 id=39% cov=82%
-IEILYRDEQILVINKPTGVATHAPQGDLALTDVERALRAQLQLEYLAIHQRLDRDTSGVMLFALDPAANANLATAFAEHTIEKTYQALVYGVPIQtQGVIDAALAPAGDGMIQVASAHDRRAQSAITHYRVL---------VSSPDQRFSLLELQPKTGRTHQLRVHCECLGHPIVGDPLY---------DVARAAPRLMLHASELRFTHPLTQQPLHIQAPTPALFTRV------------------------------
>UniRef50_C1ZB48(82-323:325) Pseudouridine synthase, RluA family n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZB48_PLALI  E=2e-51 s/c=0.85 id=31% cov=85%
-LEILFEDDSLLVINKPAGLIAHPTGEIPDGTLINAVQHYldkqstHPGLERPGIVHRLDRDTSGAMAICKEHLSHRLLSIQFQLGRISKSYLALVEGVLTDDQLVIDLPIGRAPGCSSALMSCRADALEAqasKTSLRVVERF-----------PQHTLVEAKPRTGRMHQIRIHLATIGFPIVGDEFYLKGGEIRPLvwpeservQVSLLINRQALHAACLSFAHPLTNEWQDFQAPLPDDLRQAIE----------------------------
>UniRef50_C4ZAQ6(81-295:295) Pseudouridine synthase n=15 Tax=Clostridiales RepID=C4ZAQ6_EUBR3   E=2e-51 s/c=0.95 id=25% cov=82%
-LDIAYEDDDIIVINKPFDMPAHPSAGNHDNTLANALMYYYGSQNKPFVyrcINRLDRDTTGLTIVAKHALAGGILGNAVAKRAIHRTYYAVCSGCTPACMRISAPIARKDASTIER-CVDFKRGEYAVTDFIRIKY---------NPDNNLSLVKLRLLTGRTHQIRVHMKYIGFPLIGDFLYNP--------DYTYISRQALHSGRLVFTHPVTGQKMNLISDIPSDMKSLF-----------------------------
>UniRef50_D0L1K7(111-344:346) Pseudouridine synthase n=1 Tax=Halothiobacillus neapolitanus c2 RepID=D0L1K7_HALNC  E=3e-51 s/c=0.87 id=35% cov=88%
---IVYEDEALLAVNKPAGLAVHGGSNIPFGLIELMRQ-HTGLGEKLELAHRIDRDTSGLLILAKTRATLHSLQTQFRpEGHAEKQYLAIVHGhWPDKLKRVDAPLEKWQGEGESHRVQVNPQGKEAVTHFAVLA-----------ANKNATLLRAQLETGRTHQIRVHTAHENHPIVGDEKYGQREWDKRLFPSTGAsarrrPPLLLHAYRLMLTHPQTEQPLQLTAPIPDKWRSLAQQLNL--TLPEHD----------------
>UniRef50_C0E4Q3(83-306:310) Pseudouridine synthase n=2 Tax=Corynebacterium matruchotii RepID=C0E4Q3_9CORY  E=5e-51 s/c=0.91 id=33% cov=83%
-LEILYADEDLIAVDKPVGVAAHPTVGWDGPTVVGGLAAAgyristSGPPERNGIVQRLDVGTSGVMVVAASERGYSVLKRAFKERTVSKTYHALVQGHMDPLAGTIEANIGRHPSSGWKFAVTS-DGKHAVTHYETLEAFVA-----------ASLLEVHLETGRTHQIRVHMSALHHPCCGDPMYG---ADPQLSARLGLNRQWLHAVKLGFYHPADGRWLEIESPYPPDLRHALE----------------------------
>UniRef50_C0MA80(76-291:300) Pseudouridine synthase n=6 Tax=Streptococcus RepID=C0MA80_STRE4   E=7e-51 s/c=0.94 id=32% cov=82%
-LDIVYEDEHFLILNKPAGYASIPSAIHSNtiaNFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAINKRYYALVCGqeRLPDQGEIIAPIGRTDDSIITRTVT--PKGKYAKTSYKVIARYPE----------NVSLVDITLHTGRTHQIRVHFAHLGFPLLGDDLYGG-------RLDLGMTRQALHCHHLSFTHPFTESRSDHTICLTDDFESVI-----------------------------
>UniRef50_D2M2K8(83-298:298) Pseudouridine synthase, RluA family n=1 Tax=Bacillus cellulosilyticus DSM 2522 RepID=D2M2K8_BACS4  E=1e-50 s/c=0.94 id=27% cov=82%
-LHIIFEDEHVIIINKPPHLPTIPTRNEGEPSLAgaiLAYYIENGIPSTFHAVSRLDRDTSGLVMVAKHRYMHDLCVKLQKSYEIKRSYVALVEGILsDDYNTIDLPISRKTTSIIEREVN--EFGKSAITHYEVLKRY-----------SGATLLQLTLETGRTHQIRVHMSAIGHPLLGDTLYGG--------DVRYIDRQALHSHQLSFFHPINKREYTFHCPIPDDIEDAMSKF--------------------------
>UniRef50_A6LIG6(90-304:304) Pseudouridine synthase n=5 Tax=Bacteroidales RepID=A6LIG6_PARD8   E=2e-50 s/c=0.93 id=31% cov=80%
LLRIVWEDDDLIVINKREGLLSVSTDRIKERTayrILSDYLKECDPRNKIFVLHRLDRDTSGIMMFAKNQKVKEQLQSNWSEAITQRTYVAVIEGRPEKDTDLIVSNLV-ENKHMQVYVTQDGDGKEAITRYRLLQT-----------NNRYSLVELDLETGRKNQIRAQMQSIGHPIAGDSKYG--------AETNPAGRLMLHARRLCFIHPVTGEEMRFETRIPEKF---------------------------------
>UniRef50_C9M7B4(78-297:301) Pseudouridine synthase n=1 Tax=Jonquetella anthropi E3_33 E1 RepID=C9M7B4_9BACT  E=3e-50 s/c=0.91 id=32% cov=82%
----VYADDWLAVVEKLAGIAVHPGAGRKDGTLVNGLVKTFGPlpgaGLRPGIVHRLDIGTSGLMVVARTPQAYLFLQREFSQRRVEKTYLALVHGWIPaSQGTLDGPIGRSRYDRLKMAVRAD--GRRAVTRYRTLWTR-----------GSLSLTACRIETGRTHQIRVHMASIGCYLDGDRLYGPKDVSR----HFLEGRVFLHAWRLSFHHPSDGRTMNFRSPLPDELIGVLKK---------------------------
>UniRef50_Q0A8Q9(99-317:327) Pseudouridine synthase n=4 Tax=Ectothiorhodospiraceae RepID=Q0A8Q9_ALHEH  E=4e-50 s/c=0.91 id=35% cov=84%
---ILYEDDRLLVIDKPSGLAVHGGSGLAWGLIEVLRQAR-PSAPFLELVHRLDRATSGCLMVAKRRSALRELHEQLRTGAVHKRYLALLTGALGRGPIPVEAPLER-RSGPAGGVRVASHGKLARTVFRAVARP-----------GGMTLAEADIATGRTHQIRVHAAHLGMPIAGDDRYGERAVNRRLR-GLGLKRLFLHAHRLELSAPGTGQPLSIEAPLPDELAAVVAQL--------------------------
>UniRef50_B6BNM7(78-301:325) Ribosomal large subunit pseudouridine synthase, RluA family n=1 Tax=Campylobacterales bacterium GD 1 RepID=B6BNM7_9PROT  E=5e-50 s/c=0.89 id=27% cov=84%
-VEILYEDDDVLVINKPSGVTVHPAPSVKEATLVDWLKHKGirlsniSGEERHGIVHRLDKGTSGTMVVAKNNEAHEFLSEQLQDKSMGRYYLAVLNPPLKDEITTIEqNIGRSAHNRLKMTCTDAGKSKYAKTMFKVLS---------LSNDEKQQFVACKLFTGRTHQIRVHLESINRHIIGDHIY------ALSPKAEKSERILLHAYMIYFVHPTSKEKLTFVAPLDETMKDYLDK---------------------------
>UniRef50_A4S1L0(12-243:243) Predicted protein (Fragment) n=1 Tax=Ostreococcus lucimarinus CCE9901 RepID=A4S1L0_OSTLU  E=5e-50 s/c=0.86 id=27% cov=87%
-LDVVFENDEFLVVNKPPNLRFHPNHRFEGNSLLS-RALHHMDGATPYIVHRLDMDTSGVAVFVKKQHLVANVAGQFQEKTAKKTYLAVSVGVVPPDCgdsfIVDAPIGDHGIVQEARTVDFSGEGKDARTTCEIIARATPPAAV-------AALVRVTPLTGRTHQIRVHLAHAGLPIVSDALYGPHLRWKPYDDwggALSIRRQALHAFNLELKHPETGESLTFQAKMPSDMRSVCDAL--------------------------
>UniRef50_C0F0M1(83-306:306) Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM 3353 RepID=C0F0M1_9FIRM  E=7e-50 s/c=0.89 id=31% cov=80%
-LHILYEDEDLIFVDKPAGIVSHPSKGHLSDSMINGVQayfenegREKNERSNIHLIGRLDKETSGILGIAKNSVTAERMIKQRQRGILIKEYYALVKGNPPEEGILEIPMEEmrdaRDGDKLKMKVGKSENAKTAKTFFQVVKRFE-----------KFSLVSLVIETGRTHQIRFHMASIGCPLLGDSFYGDGPE-------LGISRTALHAQQLTFTHPFCEKVMRIESEMPKDL---------------------------------
>UniRef50_A9GIV4(108-348:350) Pseudouridine synthase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GIV4_SORC5  E=2e-49 s/c=0.82 id=34% cov=88%
-IPVLHEDDALLAIDKPAGLPVHPTARYHKSTVIKMME-AARPGERLFLAHRLDRETSGVLLLCRTPEADRTVKAQFEERTgVVKRYAAIAWGWPERDTFRVELPLELDDASRykvKMRVAPPGRGLASATACEVLGRRADPLT-----GRRYALVRCTLETGRQHQIRVHLAASGLPLVGDKLYGpdegmfargaDGVLTDDDRRALELDRHALHAALLELTHPMTGERVRIEAPLSDDLRTFWDAL--------------------------
>UniRef50_Q3A3D8(66-285:301) Pseudouridine synthase n=2 Tax=Desulfuromonadales RepID=Q3A3D8_PELCD  E=2e-49 s/c=0.90 id=31% cov=83%
--HILLRDRYLVVVNKPPGINSQPTPARYKGTLYEALLrllddpYNKGRKPSLGMVQRLDRDTSGVMIFSIHARAHKSLSDIFAARRVQKHYLALVAGCMQAPQGEFRSLLARQHRTNLMKSVA-RGGKEAVTRYRVIEKF-----------GDAELLEVEIPTGRSHQIRVHFAEAGHPLLGDIRYGGPDRWRGVD----VPRQMLHARRLELLHPISKEPLNIEAPLPQDFLKLLE----------------------------
>UniRef50_A6TSZ4(86-302:308) Pseudouridine synthase n=1 Tax=Alkaliphilus metalliredigens QYMF RepID=A6TSZ4_ALKMQ  E=4e-49 s/c=0.91 id=24% cov=80%
-FNVVYEDIDVIVINKEPGIVSHPTKSHPKDTIANAaqnYLEKKGVACRIRFVNRLDMDTSGLLVIAKNPYTHHIMSQQMKANEITKKYVAFVKGVVVANEGEIDGAIYRSSDETIKRVVDDR-GQQSLTKFTVLERY-----------ADATMLEVSLLTGRTHQIRVHMESIGHPMLGDHLYG-------YVDTELIRRQALHASYLSFLQPRYKEKIEVRASLPKDL---------------------------------
>UniRef50_B7BE87(337-542:551) Pseudouridine synthase n=8 Tax=Bacteroidales RepID=B7BE87_9PORP   E=5e-49 s/c=0.95 id=35% cov=78%
-LEIVYEDESLLVVNKPAGMLSVPGKSDVD-SVYQRVRRMYPGATGPMVVHRLDMATSGLMLVAKTKEVHQNLQAQFKNRTVCKRYVAWLDGIVEEKEGHLELPLRPDPEDRPRQVVDVVHGKPAVTDYRVLRYGGCKGGLRTTP----TVVSFVPKTGRTHQLRVHSAHplgLNAPIVGDELYGKK-----------ADRLYLHAEYLGFTHPVSGVYMEVE----------------------------------------
>UniRef50_Q6KHW4(77-297:298) Pseudouridine synthase n=1 Tax=Mycoplasma mobile RepID=Q6KHW4_MYCMO   E=5e-49 s/c=0.89 id=28% cov=82%
-LDIVFENEDFLIINKRSGMVVHPAPGNMQDTLVNALLFHFKnnlsninGEIRPGIVHRIDKDTSGLLLVAKTNEAHNYFALLLKKHQIERKYQAIIVGKMDHTITNINLPIGRNTSSRLKMEVTAHNSKEAFTKITSLKASET-----------HSLIQCELKTGRTHQIRVHLAHINKPIYGDNIYGKKVDDFN---------QRLHAYELSFTY-KDNKQYSFNVPLPKEMQEDLIKFN-------------------------
>UniRef50_C0X7U3(78-297:297) Pseudouridine synthase n=21 Tax=Enterococcus faecalis RepID=C0X7U3_ENTFA  E=8e-49 s/c=0.89 id=25% cov=81%
-IEIVFEDDHFLVVNKPAGIASIPAQYHPSGTMANrvkgYYKRQNYVNQVIHVVTRLDRDTSGLMLFAKHGFAHALIDQELREKKVTKIYYALVGGAIEQlneHQLIEKPIGRDLSSLLKRQVI--ETGQFASTEYWLAKR-----------GAQAAAVRIQLHTGRTHQIRVHFEAIGCSLLGDEMYHGK-------MDQGIERQALHCMELIFTHPFTKETVHLISPLAEDMKSV------------------------------
>UniRef50_Q3AD19(77-293:301) Ribosomal large subunit pseudouridine synthase, RluA family n=1 Tax=Carboxydothermus hydrogenoformans Z-2901 RepID=Q3AD19_CARHZ  E=9e-49 s/c=0.90 id=30% cov=81%
-VKVLYEDDYLIVIDKPAGVLAHPVKNHFapsmQELTLSYYRDKGRIFEGFYPIYRLDRNTSGPMLIAKFSLIAEMLNNSLRKRQINKIYLALIEGPLaDKSGIINLPLGLLEGSIIKRAVV--PGGQPACTKYQTVKAFPT-----------HTLLKVELLTGRTHQIRAHFAAIGHPLAGDDLYGGKMD--------LIERQALHLYYISFPHPITKKTISLYAPLPRDFKEAL-----------------------------
>UniRef50_B6WA53(74-297:299) Pseudouridine synthase n=2 Tax=Anaerococcus RepID=B6WA53_9FIRM   E=1e-48 s/c=0.87 id=25% cov=81%
-LKIVYENKDYAIIDKDENVIVHPAGSIVSGTLVNGLLYHFgynnlshiGGDDRPGIVHRLDKDTTGLMVIAKSNSSYKFLKNLFETRKIDKEYLAICNGIFKKKSGEIHTFMDRDPNNRRKMAV-RNSGRDAISKYEVLSEND-----------GYSLVKIKILTGRTHQIRVHMTHINHPLLGDPVYGNVKH------KFNLDHQLLHCHKLGFTD-KDGVYREFEADVHEDFKK-------------------------------
>UniRef50_D1VZE9(82-295:315) Pseudouridine synthase, RluA family n=2 Tax=Prevotella RepID=D1VZE9_9BACT  E=1e-48 s/c=0.91 id=30% cov=82%
-VKIVYEDRYLVVIEKQAGILSMAAGHASLNVKKVLDSYFKQSKQKCtaHVVHRLDRDTSGLMIYAKDIQTAQLLEHDWHHNVYDRRYVAVVSGEMEQDEGTIANWLKDNRAYITYSSPEDNGGKFAVTHFHTLNR-----------TTEHSLVEYRLETGRKNQIRVHSADMGHPVCGDHKYGNGDN--------PIGRLCLHAYVLCFYHPVTHRPMEFETPIPPAFAHLFK----------------------------
>UniRef50_A4XKV9(77-286:292) Pseudouridine synthase n=1 Tax=Caldicellulosiruptor saccharolyticus DSM 8903 RepID=A4XKV9_CALS8  E=2e-48 s/c=0.92 id=28% cov=81%
-IDILFEDQFFLFVNKPSGIPSHPSKGHYFDTLAnNVEWYLNSQGVTSHIINRLDKDTSGIVVFAKNSYFHSIVSSEFEKRTIEKTYIAVVDGILTKKSGFIEKPISRSNDGIKREINED--GDYAITYYEVVDY-----------KNNYSILKLKPITGRTHQLRVHLASIGYPIVGDVLYGTGKNKNF--------PLLLHAYSMKFDFKLIERQYNITAPLPPYFSEFL-----------------------------
>UniRef50_C7GZU4(108-331:331) Pseudouridine synthase n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7GZU4_9FIRM  E=2e-48 s/c=0.87 id=28% cov=81%
---ILYEDDYIIVVDKPAGLLTH-AKGDKSCECTLSDkileytegsLANGSGANRPGVVHRLDRGTCGVMVMAKTDTALKHLTEAFEKQEVSKEYEAIVYDNIVRDSGVITAKIERNKKNRLKMSAGDE-GREAHTEFKVIERF-----------GKFTYVSLVIKSGRTHQIRVHMNYIHHPVLGDMLYGKRK------DKFNLMWPMLRSKKIGFLHPITSEKMEFTAAMPYEFKRIL-----------------------------
>UniRef50_Q6MEZ4(32-241:243) Pseudouridine synthase n=1 Tax=Candidatus Protochlamydia amoebophila UWE25 RepID=Q6MEZ4_PARUW  E=3e-48 s/c=0.92 id=33% cov=81%
-IQILYEDADLAIIYKPSGLLSVATAFEKGET-THALLKAHYKPRKVFVVHRLDQDTSGVMVFAFNEKTCNGLKDLFEVHDISRSYTAIVEGQLLSPSGTWKSYLYEDSQYFVHETEDETYGRLAITHYRTLKTLK-----------KYSLVELTLETGRKNQIRVHCQSAGHPVVGDKKYG--------AHTNPLKRLCLHAHLLAFKHPISRKIIRIESPIPEEFYRLI-----------------------------
>UniRef50_A4J9H9(102-315:320) Pseudouridine synthase n=2 Tax=Clostridiales RepID=A4J9H9_DESRM   E=3e-48 s/c=0.91 id=30% cov=81%
-IEVLYEDDFLLVLNKPAHQLVHPTGQTTRGTMANYLAYylkQRNVVSAIRPVHRLDRETSGCVIFAKDSRSQFILEQQLKERTLKRTYWALVKGIVhPPSGTIDAPIGPHPSLANRRAINEH--GEQSITHYQTLRSF-----------PEISLLKLNLDTGRTHQIRLHLAHLGYPIIGDRMYGVRSPW--------INRQALHAYDVSFRHLKENHEIAVHAPLPTDFAQAIN----------------------------
>UniRef50_B1H073(5-233:238) Ribosomal large subunit pseudouridine synthase C n=1 Tax=uncultured Termite group 1 bacterium phylotype Rs-D17 RepID=B1H073_UNCTG  E=5e-48 s/c=0.84 id=33% cov=84%
-IEIIYQDENILVVNKPSGMFVIPGRNIYENK-TLVEILRNQLKQKLWVVHIIDRDASGVLVFAKNPETHRNISVQFENSKIRKKYIALLSGVLEENEGTINKPLIISGKN----VRIDITGKESITDFKVLENFRS-----------YTLVNALPLTVKRHQIRIHFWSLGHPLAIDGEYGtldpiflssfkrGYKIKKGKTENPLISRLTLHAAALTLILPGSGEEKTFEAALAKDFEVAVKQL--------------------------
>UniRef50_C8PT91(79-319:326) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PT91_9SPIO  E=5e-47 s/c=0.79 id=29% cov=82%
-LQILYEDNDVIAVNKRVGMVTHPAAGNWTGTLVQALAYyrlhtspihdkfaglleaeqgrgNFEDLLRAGIVHRLDKDTSGVLITARSAAAEAFLKDEFKMRRTEKYYAAILNGVPeKRTGVIETSVFRDEHSRIRFTASADlAKGKYARSRYKVLRVY-----------GRYALVLFKIDTGRTHQIRLHARFIGCPIVGDPLYGKKEAEWKPY------GMMLHAYRLCVALPSTREKTVFTAPLPRRFQTVL-----------------------------
>UniRef50_Q4A7R4(82-301:304) Pseudouridine synthase n=5 Tax=Mycoplasma hyopneumoniae RepID=Q4A7R4_MYCH7  E=1e-46 s/c=0.85 id=27% cov=83%
-FEIIFQDQNMILINKPKNLVVHPGVGNWKNTLVNglishFDSLEQLDHIRPGIVHRLDKDTTGLLLVAKNAKAHSFFVNELANRQIKRFYKAIVIGKVLHKFMKINLPIGRDLKNPLKKTISFFNSKPAITNVELIKHF-------NYQNQDFSLVKCQLETGRTHQIRLHLAHIGYPIYGDPIYGKKIDEL---------GQRLHAYKLVFKD-LNGLSREFQADLPEEFNIAFEQ---------------------------
>UniRef50_D1RB93(68-280:283) Pseudouridine synthase n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1RB93_9CHLA  E=1e-46 s/c=0.88 id=29% cov=82%
-VPILYEDAHLVVIEKPAGLLSVATNFDKAKTAHAFLKERYR-PRKVYVVHRLDQDTSGVMLFALTGEAFFGLKALFADHDIDREYTAVVHGKMTQQEGTWQSYLYEDKAYVVHSTQDPDKGELAITHFKTVEART-----------HFSLLNLKLETGKKNQIRVHCEDHGFPIVGDKKYGGE------GESHITKRLCLHAHHLGFVHPIYKKEMSFDSPIPEKFYQCLK----------------------------
>UniRef50_B9XHZ1(379-593:599) Pseudouridine synthase, RluA family n=2 Tax=Verrucomicrobiales RepID=B9XHZ1_9BACT  E=1e-46 s/c=0.87 id=25% cov=82%
-IQILHEDEALIVLNKPAPLPMHAGGRFNRNTLE-YILHQVYHPQKPRAAHRLDANTSGVVLVTRTRHFASHLQPQFAHGEVGKFYLVKVQGTPKEDSFSCNAPISAEPSEAGAREVDFEEGLPSRTEFRVLQRNAD----------GTTLLEARPLTGRTNQIRVHLWQMGLPVCGDPVYlPGNKLGETQTLRVEDAPLCLHAWRVTFLHPLHRQRMEFTAPKPE-----------------------------------
>UniRef50_B7GQ28(79-291:320) Pseudouridine synthase, RluA family n=21 Tax=Bifidobacteriaceae RepID=B7GQ28_BIFLI  E=2e-46 s/c=0.88 id=31% cov=80%
---VVYEDDDVIVVDKPVGVAAHASVGWTGPTVLGSLRDRgvhiasYGAAGREGIVSRLDVGTSGLMLVCKSDLAYTEMRRQFAEHEVKKTYHALVQGGLKENKATIEAPIGRAKVSDFRFCVT-PAGKPAVTHWDVLERF----------GHEATLVSVNLETGRTHQIRVHFSSIGHPLCGDPMYG---ANPVLSEALGLDRQWLHAMKLEFRHPRTRVWTTVRSQYP------------------------------------
>UniRef50_C7RGL6(74-297:305) Pseudouridine synthase, RluA family n=3 Tax=Anaerococcus RepID=C7RGL6_ANAPD  E=2e-46 s/c=0.84 id=27% cov=81%
-LKIVYENDDYAIIDKDSNVIVHPAGKIITGTLVNGLLGRYgydglshiGGDDRPGIVHRLDKDTTGLIAITKTNEAYKYFKKMFETRKVDKYYYAIVFGNFDKKKGTIDNFMDRDVHNRRKMAV-RNTGRRAVSHYEVISEVE-----------GFSLVRIKIETGRTHQIRVHMTHINHPILGDPVYGNVKH------KFNLDHQLLHCGKVGFKN-MEGDYVTYEAIPHEDFLK-------------------------------
>UniRef50_Q1WSL9(78-295:295) Pseudouridine synthase n=3 Tax=Lactobacillus RepID=Q1WSL9_LACS1   E=5e-46 s/c=0.85 id=26% cov=82%
-IKILYEDDNYLLVDKPAFVASIPSPLHPNDSLVNrvvgYYQIRGYRGIIPHIVTRLDRDTSGIVIFAKHRYAHALLDSQLKEHKISKTYTAILSGILHNNHyIIDLPIGRDSTSLIKRKVLFSEKAKRSKTEIFVEERIR-----------DNTLCKIKLHTGRTHQIRVHCSYLGYPLVSDTLYGG-------TISMPLQRQALHCSEVVFWDQFSSQYIKVKSNISQDMMNYLK----------------------------
>UniRef50_B2S2T6(90-331:331) Putative uncharacterized protein n=2 Tax=Treponema pallidum RepID=B2S2T6_TREPS  E=5e-46 s/c=0.77 id=26% cov=85%
-LSILFENEDIIAVNKAQGMIVHPGAGHWTGTLVQALSfyrvYRARFEDEFsrqfqkgfpdffstlrqGIVHRLDKDTSGVLLTSRNMHAHEALVRSFKKRQVRKVYLALLQGVPARGVGVIETTIVRDRRRRTRFVASEDfsKGKYARTRYKVMK-----------ICGACAFVQFLLDTGRTHQIRVHARYLGCPVVGDPLYGSRNICGIPTT------LMLHAYAVRFVLPRTKKRITLVAPIPLRFVRLIHRLSVR-----------------------
>UniRef50_A6FJ39(29-238:238) Pseudouridine synthase n=1 Tax=Moritella sp. PE36 RepID=A6FJ39_9GAMM  E=6e-46 s/c=0.89 id=33% cov=80%
-LEILYSDNDLVVINKPAGLLSVASANENKQHALAILrkqLSHAKNSVALWPVHRLDRDTSGVLMFATSREMRDAVNEGWS--GAEKTYLAVVEGSPKPSQGRIDQPLRMDPEKYQMIVGPHSEAKNAVTHFKTLRTVK-----------ELTLLEVKLETGRQHQIRVHMAWLGHSVIGDPRYGTDG-----------PRMGLHALSLSITRPNTGKRLTFEAPAPVEFLDLL-----------------------------
>UniRef50_UPI00016B2413(177-379:379) ribosomal large subunit pseudouridine synthase, RluD subfamily protein n=3 Tax=candidate division TM7 RepID=UPI00016B2413  E=7e-46 s/c=0.92 id=34% cov=77%
----IYEDNDIIVINKPAGMLTHAKGAIAEE-FTAADIVKpitnyKADTNRPGIIHRLDRNTSGVLLMVKNSDAASKIQKQFSQRTVKKTYYAIVCGIPYQHKALIDLPIERNPS-RPSTFRVGVNGKSAQTSYEVERSI---------IKKNISLIKLQPKTGRTHQLRVHMQYLNTPILGDLVYGGK----------PAERMFLHAESLEVTL-LSGERKVFKAPLP------------------------------------
>UniRef50_P0A5T2(83-308:308) Uncharacterized RNA pseudouridine synthase Rv1540/MT1592 n=131 Tax=Actinobacteria (class) RepID=Y1540_MYCTU  E=9e-46 s/c=0.82 id=31% cov=82%
---ILYSDDDIVAVDKPAAVAAHASVGWTGPTVLGGLAAAgyrittSGVHERQGIVHRLDVGTSGVMVVAISERAYTVLKRAFKYRTVDKRYHALVQGHPdPSSGTIDAPIGRHRGHEWKFAIT--KNGRHSLTHYDTLEAFVA-----------ASLLDVHLETGRTHQIRVHFAALHHPCCGDLVYG---ADPKLAKRLGLDRQWLHARSLAFAHPADGRRVEIVSPYPADLQHALK----------------------------
>UniRef50_B1CC12(97-302:305) Pseudouridine synthase n=1 Tax=Anaerofustis stercorihominis DSM 17244 RepID=B1CC12_9FIRM  E=2e-45 s/c=0.90 id=25% cov=78%
------------VINKKPGMVVHVTKSHPLDTLQNAIYHKWEIEKkhfKTRFVNRLDMDTSGIVVIAKNKYVHHFIQNQSINNQIDKKYVLIVDGIMDQKEGYINAPIKRAEGHPLRRIVA-EDGKECITKYKVIEEFK-----------NHSLVEAKLITGRTHQLRVHFSYVGHPILGDSLYNENK-------SELISHQALHAKSISFVHPRGNKPMTFEAELFDDFKDVLE----------------------------
>UniRef50_D1AL10(72-283:283) Pseudouridine synthase, RluA family n=14 Tax=Fusobacteriaceae RepID=D1AL10_SEBTE  E=4e-45 s/c=0.86 id=27% cov=80%
-LDIVFEDEDILVVNKQPYLVTHPTKKKVDVTLANgiVYYFQEKYGKEmvPRFYNRLDMDTSGLIIIAKNSFTQAFLQN---FGDVKKYYMALVHGIIKEEMINIEKPIARVGDDLRRKILDE--GQYAKTVVKTIKRNE---------EKNITLTECELFTGRTHQIRVHLSNEGYPILGDKLYGDMDDN--------VKRQMLHSYKVSFIHPRTKERKELEIEMYDDMKEFM-----------------------------
>UniRef50_UPI000178A5E6(82-295:302) pseudouridine synthase, RluA family n=1 Tax=Geobacillus sp. Y412MC10 RepID=UPI000178A5E6  E=6e-45 s/c=0.86 id=31% cov=80%
-LQVLYEDDFCLVVNKPAGLAVHPDNESRETTLnhvVAAYYEAEGIHAAVRHIHRLDKDTTGPVLYAKNEYAQLKLDEAMREKKIVRMYAAIVQGRVSQElKRIDLPIGKDRYHASRR--RVSLTGQAAITHI-----------LSAEAYPKASLLHIRLETGRTHQIRVHLSHMGHPLLGDVLYGGPGT---------FARQALHGERLLFHHPFTGESIEVPAPWPQDMMEL------------------------------
>UniRef50_D1PU24(222-417:421) Pseudouridine synthase n=1 Tax=Prevotella bergensis DSM 17361 RepID=D1PU24_9BACT  E=6e-45 s/c=0.93 id=35% cov=75%
-LKIVYEDDTLCVVDKPAGMLSVPGKGCRESVLDVMRR-RCPDATGALVVHRLDMATSGLMVVAKTAEAYRELQRQFATRSVRKRYVAILSRQPREPKGEIALPLRPDLDDRPRQVVDSVYGKPALTHYEII---------------DGCRVALYPRTGRTHQLRVHCAHrdgLDSPIKGDELYG-----------RRAERLYLHAEWLAFRHPATGEEVEFTS---------------------------------------
>UniRef50_B8K915(23-249:254) Pseudouridine synthase n=5 Tax=Vibrio RepID=B8K915_VIBPA   E=8e-45 s/c=0.80 id=32% cov=75%
-VDIVFEDEHILVANKPSGLLSVPGRLEEHYDSLWSRLVA--IYPDIQVVHRLDMDTSGLMLLAKHKEAERSLKKQFQYRLTHKVYYARVWGHPTNDNGEIDLPLICDWPNRPRQIVCFDDGKPSKTLYQVVKREE-----------RTSIVRLLPITGRSHQLRVHMQALGHPIVGDEFYSEGEAFEFS------DRLELHAAELSFYHPHS-----------------------------------------------
>UniRef50_C1TRW2(82-296:305) Pseudouridine synthase n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TRW2_9BACT  E=1e-44 s/c=0.85 id=32% cov=81%
----VYRDESLWVVSKPAGLLSQPDKKG--GDSVVTRAFLPGSSFQPQAVNRLDRNTSGIMVLALTGESLRDLSSRWRDGEMEKVYLALVVGDLPEEGSIDAPLSKDGSSNK---VFVDSKGQSSLTLYRRLAS-----------GGGLSLCLVTLITGRSHQIRVHMSHIGHPVLGDVKYGDRALNGV----KGAKRPMLHAFSVSFPD-MSGDlsslsSKTFRTPMPEDMADMCSKNG-------------------------
>UniRef50_C7QW59(344-550:551) Pseudouridine synthase n=5 Tax=Cyanobacteria RepID=C7QW59_CYAP0   E=1e-44 s/c=0.88 id=30% cov=77%
-IKVIYEDQWIIAIDKPSGLLSVPGRYFETFDSVLTRLQNSlPDAQELRTVHRLDQDTSGILLLARDRYTHRHLSQQFAQRKVEKIYEAILAGSVMMNEGVIQLPLWGDPNNRPYQKVDWELGKPSITQFKVITTQE-----------NLTRIQFIPLTGRTHQIRVHAvdtQGLGSVILGDYLYGCNA---------GVSRLHLHARELKFEHPQQQKTVHL-----------------------------------------
>UniRef50_Q26D11(359-560:561) Pseudouridine synthase n=2 Tax=Flavobacteria RepID=Q26D11_9BACT   E=1e-44 s/c=0.90 id=30% cov=77%
--EVIYEDDAIIIVNKPEEFLSVPGKTIKDSVYSRLKEL-YPDATGPILVHRLDMSTSGILVATKNLEYYHFIQEQFINRTISKRYVALLNGVLENNEGMIELPLRVDLDNRPTQLVCYEYGKSARTKYQVLERREKE-----------TLVHFYPITGRTHQLRVHAAHasgLNAPIVGDDLYGTAT-----------NRLHLHAEFIKFIHPITHKTVSFKAPVP------------------------------------
>UniRef50_Q7UQ77(29-248:256) Ribosomal large subunit pseudouridine synthase D n=1 Tax=Rhodopirellula baltica RepID=Q7UQ77_RHOBA  E=2e-44 s/c=0.82 id=29% cov=82%
-VDVIYEDNHLLVVNKPTKLATMGAAGqptlHSLGCDYIRRTCNKPNKVYLGIVSRLDSMTSGVIVMARTSKAASRLTPQFANHSgdgAKKTYLAVVSGRVEQQQGTlvDDVYKDDAAHRMRVAHHSRSDAKEARLEYEVLGC-----------DRELTLLMVKPLTGRKHQIRLQWAEVGFPILGDTKYGSERSWPTG--------IALHSWRLSIMHPTKKERMTFEAPIPDAWASRL-----------------------------
>UniRef50_Q03PR9(76-291:294) Pseudouridylate synthase, 23S RNA-specific n=1 Tax=Lactobacillus brevis ATCC 367 RepID=Q03PR9_LACBA  E=2e-44 s/c=0.84 id=30% cov=82%
-ITVLFENRDWLVVDKPAGLNVVPGPANRTDTLVNrikgYWEAEHAENLVPHILTRLDRFTSGVVWVARHRLANSLASQLQAAHQIDKRYLAVVSGRLEaDHAVIDAPLASDPTGYNQM---VSPTGKPARTEYWVQQRFAT-----------ATVVAVKLHTGRTHQIRAHFASLGHPLLGDALYDGPV--------TGINRQALQALSLTFKDPFTDEQRQFTSELPADWQTLIHQL--------------------------
>UniRef50_Q5LC96(87-302:305) Pseudouridine synthase n=29 Tax=Bacteroides RepID=Q5LC96_BACFN   E=2e-44 s/c=0.84 id=28% cov=82%
LLKIVYEDAYIIVVEKKEGLLSVGTERQKERTaqhILSEYVGRSGRGNRIYVVHRLDRDTSGLMMFAKDEKTQYTLRDHWHDIVTDRRYVAVVTGEMEKDSDTVVSWLTDRTLYVSSSSYDDGGSK-SITHYRTIKR-----------ANGYSLVELRLETGRKNQIRVHMQDLGHPLIGDGRYG------IDGGPNPLGRLALHAFKLCFYHPVTDQLMEFETPYPPTFKKLF-----------------------------
>UniRef50_B1X0W4(83-299:304) Pseudouridine synthase n=2 Tax=Cyanothece RepID=B1X0W4_CYAA5   E=4e-44 s/c=0.83 id=28% cov=80%
-FDLIYEDHHILVINKPSGLPVLPGGGFLEHTL-LGQLKKQYPKEKVFPIHRLGRGTSGLMLMGKTAIARSHLTRQMREHKMRKVYRTLIgENNLPDYFNIEHPIGKISDPVLGYIYGAKADGKDAYSQCQIIERY-----------SDKTLVEVTILTGRPHQIRIHLATIGYPLLGDPLYvvggipkTGFKEQKETVNVPGDCGYFLHAYQLSFVHPATHQCLTFTC---------------------------------------
>UniRef50_C9AAU2(81-281:284) Pseudouridine synthase n=4 Tax=Enterococcus RepID=C9AAU2_ENTCA   E=7e-44 s/c=0.89 id=31% cov=77%
-VDVLFEDEHLLVLNKPAGVKTHPNQPLEADTLLNdAAAYLAPKQQQPYVVHRLDKETSGVVLFAKNPLVLPILGRMLENKQIFRRYQATVWGKLTQDQTIAKKIGRDRHDRRKRI-IDPRNGQSAITHVTI-----------AHTQQKTTDVYCVLDTGRTHQIRVHLASIGHPVVGDPLY----------QNKPAPRLLLHGYELHLEHPFTKEQLVIIA---------------------------------------
>UniRef50_B7VRG6(360-560:563) Pseudouridine synthase n=4 Tax=Vibrionales RepID=B7VRG6_VIBSL   E=7e-44 s/c=0.89 id=33% cov=77%
-FDIVYEDDEIVVVNKPEEFLSVPGKFIEDSVYTRI-KARYPDATGPLIIHRLDMSTSGLLILALTAESNKHIQKQFIDRTVEKRYTALLDGEIDGKSGDISLPLRGDITDRPRQLVCHEHGRNAETHWEAVST-----------NNGKTKVHLYPKTGRTHQLRVHCAHpsgLGVPIRGDDLYGYKRE-----------RLHLHAGYLKLIHPTTGEWIEFEVP--------------------------------------
>UniRef50_Q5E092(373-576:576) Pseudouridine synthase n=3 Tax=Aliivibrio RepID=Q5E092_VIBF1   E=9e-44 s/c=0.88 id=34% cov=78%
-LEIVYEDDVLVIVNKPVEFLSV-SGKYISDSVHARIQARYPNATGPLIVHRLDMSTSGLLVLTLTAESNKQVQKQFIERTVEKRYTALLEGNIETDNGTINLPLTGDMEDRPRQMVNHKSGRKAETHYQVIAQ-----------EGKRTKVHLYPHTGRTHQLRVHCAHqagLNTPIVGDDLYG-----------FKADRLHLHAGYLKFKHPTTNETVEFSC--PEDF---------------------------------
>UniRef50_D0LUH1(96-295:303) Pseudouridine synthase n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LUH1_HALO1  E=1e-43 s/c=0.89 id=28% cov=77%
-FKIVFEDRDLVVVDKPAGLLSAPTPESDLGNLAALLRERR---ERVYVVHRIDLQTSGLLVFAKTRRANQHLSERFREHQIERAYTAVVAGAPVEDTFTIDLPLR---------------GRRATTHLQVLQRI----------GERAAVLDARLETGRTHQIRLHCLQRGYPVLGDPQYGER-----MSDELTPPRMALHARVLGFEHPRSGEARRFESELPADLGDWLA----------------------------
>UniRef50_C5ZWU1(65-307:319) Pseudouridine synthase n=2 Tax=Helicobacter canadensis MIT 98-5491 RepID=C5ZWU1_9HELI  E=2e-43 s/c=0.73 id=26% cov=90%
-IPILYEDEDLLILNKPINLIVHQTHQDDSQ-YTLQDWLQEnnfslsnlGDSYRQGIIHRLDKTTSGAIVIAKNNYAHEILSQQLKSKEMGRYYVCVIDSPLKQNILIDAPLIRHPKNRLKYIptTKDTPLSKEAKTAFFKI-----------INNDKIELIGAKLFSGRTHQIRAHLSKIQRHILGDVFYGYKGNYTA--------RILLHSHLVYLTHPTTKQRLEIYAPLWEDMLLFLHQEFYSSQSYENFAKNFKIPLEQ------
>UniRef50_A9GEI0(8-237:241) Pseudouridine synthase n=2 Tax=Myxococcales RepID=A9GEI0_SORC5   E=1e-42 s/c=0.76 id=45% cov=82%
-LSLLHLDDRVAAFAKPSGLLVHRGWGDAP--VVFVDLAERALGRKVYPVHRLDRATSGVLLVALDPAAAALLCAQFEQGLARKRYLALVRGVPPEHGCVDHPIPRREGGPRV----------PAVTDFERLHALE-----------RYAVVEARPRTGRLHQVRRHLKHISHPIIGDVNYGKGEHNRLFRERYALHRLALHAAELAVAHPETGAPLRVAAPLPDDLRGPFDQLG-------------------------
>UniRef50_C7PHX6(368-568:570) Pseudouridine synthase n=1 Tax=Chitinophaga pinensis DSM 2588 RepID=C7PHX6_CHIPD  E=1e-42 s/c=0.87 id=29% cov=77%
-LDIIYQDESVVVVNKPSGLRSVPGVTIQDSVYT--RLKHALGDIEPLIVHRLDMDTSGLLVVAKTQAAHKHIQRQFLQRTVSKRYTALLSKVIDTSEGEIDLPLTADLFNRPRQIVCFTTGKKSVTRWKVVTRYQA-----------MTKIDFWPLTGRTHQLRMHSAHplgLNAPIVGDDLYGTAAE-----------RMYLHAAHIEFTHPLSRQRISFDAPV-------------------------------------
>UniRef50_A6GHA7(87-312:324) Pseudouridine synthase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6GHA7_9DELT  E=2e-42 s/c=0.77 id=29% cov=82%
-LTVVHEDASLLVLDKPAGMVVHAGPGHDSGTLVNAVLHHLQvhadalpvlpgnGPERPGVVHRLDKDTSGLIVFARGLRAQTVLAEQFRDHSIDRAYLGVVLGRPSFERRRLETTHGRDPADRRRFA-PDQGTRRAVTTMEVL----------RPLGAHAALARFTLETGRTHQIRMHARMVGHPIFADPLYGRRPKHPALRRlADGLGRHALHAALLGFAHPDGSGRLVLEAPLPP-----------------------------------
>UniRef50_B5JHH9(89-322:324) Pseudouridine synthase n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JHH9_9BACT  E=2e-42 s/c=0.74 id=28% cov=82%
---IVYFDEHIVVVNKAAGLMTVPhpesDETETLDRLVNDYLRIRDPDAKtnrasLGVVHRIDKDTSGLVVFARTFLAKRALSEQFRAHSIERRYLAIVHGELKAQSIRTHLVRETGDGLRGSAPKgatnseGEELGRLAITHVDVVERL-----------AGATLVSCRIETGRTHQIRIHLSEIGHPIVGEKVY----IRGFEGELIPANRAMLHAAELGFIHPGSGEAVSWQEEASKDFQR-------------------------------
>UniRef50_C6LHC3(101-328:342) Ribosomal large subunit pseudouridine synthase, RluD family n=1 Tax=Bryantella formatexigens DSM 14469 RepID=C6LHC3_9FIRM  E=2e-42 s/c=0.76 id=30% cov=80%
-LHILYEDEDLICVWKEAGMVLHPAHGHYSDSLANYlqgYLAGKGGQEQVRGIGRLDKDTSGIVVFARNRIAAARLWQQRQSGRFQKEYVALCEGVFPdeayeREQTIDAPIQKVTGEKNKMCIVQERccpaAGCFAVTHYRAISEKESCfheamrllSAGDLPGPEQASLVRLHLETGRTHQIRVHMAYIGHPLVGDAVYGRGIAGQTCAK--------LCAWRARLVQPFTGETI-------------------------------------------
>UniRef50_B8GBL0(78-307:307) Pseudouridine synthase n=3 Tax=Chloroflexus RepID=B8GBL0_CHLAD   E=8e-42 s/c=0.75 id=26% cov=87%
--HIIYEDDDLLVINKPPACYTGDTPWDTQGSVLAVARRllteRDGLVPTLHLAHQLDAGTSGILVISKHPRANAPLQAAFNHGQVDKRYLALCAGHPPTATELITGHGR-AAAGRWRLYEQAEIGKVLPNGQRV--KRAHTQIELRRQYGDVALVWAKPLTGRTHQIRLHLVALGCPLLGDERYGG----PTTVAGMLIPHPLLHAAELALPHPRSGRLLNIFCPPPSIFTGVLKCFG-------------------------
>UniRef50_C0WQT7(87-296:302) Pseudouridine synthase n=3 Tax=Lactobacillus RepID=C0WQT7_LACBU   E=1e-41 s/c=0.82 id=26% cov=80%
-LKILYEDANLIVINKRRGNKTHPNqPGEVGATINHLAAYLKTKEALPYMVHRLDQETSGAILFAKNPAVVPTLVAKIATKNIKRTYLAWVVGTDIDSQGIIDFPIGLDPNDKRKRMIDGNHPAKSITHYTVLQKED-----------GYSLLAVQLETGRTHQIRVHLTAIGHPLVGDPLYNPDDKHPF---------LLLHSWKLNIPLPFSEQVIEITAPLPAHF---------------------------------
>UniRef50_A6Q113(70-285:299) Pseudouridine synthase n=1 Tax=Nitratiruptor sp. SB155-2 RepID=A6Q113_NITSB  E=1e-41 s/c=0.80 id=34% cov=77%
-LKPIFETKDFVLYDKPSGIMVHPRNRNTHYTL--IDEIRYRYGPQANIVHRIDKETSGLVLASTNKEAEKALKQMFEHKQIQKRYLALVRGNIEKQLVIEEPIALNRDYSKIKLKVKiDPSGKYAKTIINPLKQF-----------GSFTLVEAIPITGRQHQIRIHLFHVKHPILGDPIYGPSTNESIRYLDglmdeeerlvvTGATRLMLHAYAVEFTYNDTK----------------------------------------------
>UniRef50_UPI000196C29C(83-287:289) hypothetical protein CATMIT_02934 n=1 Tax=Catenibacterium mitsuokai DSM 15897 RepID=UPI000196C29C  E=1e-41 s/c=0.84 id=29% cov=78%
-IDIVYEDDLILVVNKPIGIAVYPDDPHKTDSLSNrvsAYYMTQGYDIPVRYIHRLDNDTSGLVVFCKCHLIQAYLDHALSIKEIQREYLAYVEGHIKEGKEYKIEQNLGKDRHSPSKMRVHSKGISAVTYYQCLENKE-----------DHALVRCRLETGRKHQIRVHMASIGHPILGDSLY---------NEGSDYPRLALHAAYIKFEEPITHLEIDLYSPM-------------------------------------
>UniRef50_A1VXA1(69-277:300) Pseudouridine synthase n=18 Tax=Campylobacter RepID=A1VXA1_CAMJJ   E=4e-41 s/c=0.81 id=29% cov=75%
-VEIVFENEDFAILEKESGILSHPNGRHCKYSLS--DEIWHLWGKEACVAHRLDKETSGLILIAKNKKAQIDLKSLFEKKLVQKEYLALAHGKIEENFIVDKAInlTKNYDDVKTRMQICKE-GKQAITEFEILEYF---------PKINATLLLCKPLTGRQHQIRVHLHYKNHTILGDPLYGLSKQQIESILDEKLNpkerlkltgalRLCLHSYRLKF----------------------------------------------------
>UniRef50_B2J8D4(368-571:575) Pseudouridine synthase n=7 Tax=Cyanobacteria RepID=B2J8D4_NOSP7   E=6e-41 s/c=0.83 id=34% cov=77%
-LPIIYEDEWLIAVNKPPGLLSVPGRyRDRQDSVLSRLRHLLPDGMALASVHRLDQETSGILLLARDRQTHKQLSQQFQQRQVHKVYEAILSGVAIAEKGVIDLPLWGDPENRPYQKVDWQNGKPSLTQFQVISR-----------EQDYTRIEFTPLTGRTHQLRVHAAdvrGLGITILGDRLYGCDAVT---------SRLYLHARELDFEHPQLKKTLYLKA---------------------------------------
>UniRef50_UPI0001C353AC(6-218:239) putative pseudouridylate synthase n=1 Tax=Clostridium hathewayi DSM 13479 RepID=UPI0001C353AC  E=1e-40 s/c=0.79 id=30% cov=80%
--NILYEDDQIIVVEKPAGIESQSSRTFEPDMVSevkkhINSLSPKKGDPYVGVIHRLDKPVGGILVFGKTKEAAGALSKQISEHQTEKRYLAVVCGKPvENFGTYVDYLWKDGKNNISKIVDKGiTDAKRAELSYRVLAELE-------GEGGPLCLMEIDLKTGRHHQIRVQLSGHGTPLLGDLKY-----NPDGPKVTGQRNVALCAWKLSFTHPGNKKRMKFT----------------------------------------
>UniRef50_A0YGE0(15-212:221) Pseudouridine synthase n=1 Tax=marine gamma proteobacterium HTCC2143 RepID=A0YGE0_9GAMM  E=1e-40 s/c=0.85 id=32% cov=77%
-VEILFTDDDLLLVNKPAGLLSVPG-RHPANKDCLITRVQRQYA-DARIVHRLDMDTSGIMVLALSADSHRALSQLFAERKIIKEYEANVYGTIIDDHRLIDLPLLCDWPNRPRQKVDFHHGKNAQTWVERVSQHPD----------GWTRVLLKPVTGRSHQLRVHLAEIGHPILGCEFYAHQRAVSM------ADRLQLHATKLEFCHPNSGETI-------------------------------------------
>UniRef50_C0EY52(139-399:422) Pseudouridine synthase n=1 Tax=Eubacterium hallii DSM 3353 RepID=C0EY52_9FIRM  E=2e-40 s/c=0.64 id=28% cov=94%
-VRVLYSSEDILVFHKPAGMLSQRakASDDSLNDYLIDYCIQTGIiskeelaGFRPSIANRLDRNTSGIVLAGISIKGLQRLASMLRERTLGKYYLCLVEGKVKEDARIAGYLTKEEKNNKVSLHKEKaEGASYIETEYKVLKSTD-----------KASLLKIRLITGKSHQIRGHLASVGHPVFGDYKYGNRDFNNQIKWKDGVNYQLLHSYELVVPE-GTGELfgLHIIDPVPEVFHKVQTRWGLEvpELSYENEAKNRETDNKRAG----
>UniRef50_A7NF15(77-295:309) Pseudouridine synthase n=2 Tax=Roseiflexus RepID=A7NF15_ROSCS   E=2e-40 s/c=0.77 id=30% cov=80%
---ILYEDADLIALDKPIDTYVEATPWDAEGHLRAALAHflevRDGSAPPLHLAHRLDRDTSGVLLLSKAPDVNAALQRAFREGAVRKTYLALCAGLPAFDEIEIETGHGRGRGGVFRVFPHEEIGralpqggtvKAMRTRLRVVRRMD-----------DAALACATPLTGRTHQIRLHLAFLGHPLIGDVKYGGPSTWRGVV----VQHHHLHAWRLELPHPRSGTALIIESPAP------------------------------------
>UniRef50_B6W8A0(73-278:282) Pseudouridine synthase n=2 Tax=Anaerococcus RepID=B6W8A0_9FIRM   E=2e-40 s/c=0.81 id=26% cov=75%
-IKILYEDKDIVAVDKPPNLTVNSKNQESLSNYLAYYFKENKIKSQIRLINRLDMNTSGIMLVAKNPFSHAYYQNQIENNELDKEYLALVEGNLIIDDFCEIDIDYDKENKKMKVVSDKNHVK---TYFKTLKNY-----------GKFSLIYCKIYTGKTHQIRLSLAYLNHPILGDNLYGS---------KYDIERFLLHAYRIKFKSFRDQKKITI-----------------------------------------
>UniRef50_C3YH76(96-261:369) Putative uncharacterized protein n=1 Tax=Branchiostoma floridae RepID=C3YH76_BRAFL  E=3e-40 s/c=1.01 id=31% cov=64%
-VQIVEETDDLVVINKPASMPVHPCGGYRHNS-VIFVLGKEHGFQNLHPIHRLDRLTSGILIFAKNLETKHRLDAQIKGREVKKVYLARVEGEFPEKAECDKPIFAVKHKLG--VCRVCPEGKPAKTTFERVS-----------FDGKSSVVRCFPETGRMHQIRVHLQYLGHPIVNDPLY-------------------------------------------------------------------------------
>UniRef50_A4ANB8(104-307:308) Pseudouridine synthase n=3 Tax=Flavobacteriales RepID=A4ANB8_9FLAO   E=4e-40 s/c=0.82 id=33% cov=77%
-LKMLYEDEHLAAIHKPSGILV---SGNSFKTITHALSQNLEpsnlpDSTLPQPVHRLDYATTGILLIGKTSSVIRALNGMFERKEIKKTYYAITMGKMEIRGEVTLKI----------------DNKNAQSKYVVEETV------PSERFGQLNLVKLTPITGRRHQLRIHMSGIGNPILGDSDYGTKDLILKG------KGLYLHAYSIEFNHPYTNEKLLIKSEFPKRFKKIF-----------------------------
>UniRef50_A8TF58(105-366:372) Pseudouridine synthase n=1 Tax=Methanococcus voltae A3 RepID=A8TF58_METVO  E=4e-40 s/c=0.64 id=23% cov=87%
--DIMYEDMDILVVNKPKNMVVHPTKTIKSGTLANaiMDYQNHNKSEserfKIRFINRIDMDTTGIVLIAKNSFAHQKIANQFQGC-MKKEYLAVISGNMDvdnldtnlnnsldtelnnnlNDEKYNLPLnlrlkIYKENNSKFSVIIFDRDTDELIehTNFEIIKntkdTKDNKDNKDTEISNNFTLIKASLITGKTHQIRRHLAYLGFSIVGDELYTNNNELNDNFKNYS---LMLHSYKTTFIHPRTNELIELIEEPPKDFKILL-----------------------------
>UniRef50_B2AE77(144-348:479) Predicted CDS Pa_4_3110 n=9 Tax=Leotiomyceta RepID=B2AE77_PODAN   E=1e-39 s/c=0.80 id=29% cov=69%
-VQVIHEDDDMIVINKPSGVPVHPAGRYHYNSVVEIMKAERGPTFAPRPCNRLDRLTSGIMFIAKTAKAAESLSAQIFRRSVRKEYLARVVGRFPDgEVVCDQPILQISPKLG--LNRVRANGKSAKTVFKRLAYYPSPIIKPSssnspspdeaetggpedqftRETEGYSIVRCLPVTGRTHQIRVHLQFLGHPVQNDPIY-------------------------------------------------------------------------------
>UniRef50_Q2GKG0(77-284:297) Pseudouridine synthase n=4 Tax=Anaplasma RepID=Q2GKG0_ANAPZ   E=1e-39 s/c=0.79 id=28% cov=80%
--NIIYKDENIIAINKPAGVNVQGGTK---VSISLSDLLNKIIpGEQLHIVHRLDRDTSGVLIIARGQSIARILSEELRFRRVRKEYIAVTKGVPAFSKGEITMPIYCKKQSG---VGETLIPKEAKTVFSVLQSSK-----------RHAVMLLSPVTGRKHQLRIHLSQFCCPIIGDTKYSKDTEVQQHNS------LHLHAFRTSFQ--LFDREIVIKAPVPEYMIATINEL--------------------------
>UniRef50_Q12L72(27-224:230) Pseudouridine synthase n=17 Tax=Shewanella RepID=Q12L72_SHEDO   E=1e-39 s/c=0.83 id=34% cov=76%
-LDIRYLDRDIIVINKPSGLLSNPGRAPETYDTAITRLQRLY--PETILIHRLDCDTSGIMIFARNKKAESNLKTQFQNRQAKKVYIAEVSGCFEHQdGKVNFPLGPDPMTPPFQQVIES--GKPALTYYRLLEHRAS-----------TSLVELKPHTGRTHQLRVHMKALGHTIIGDEFYGDETVIAAS------HRLNLHAQSLTLLHPFKQIEIQF-----------------------------------------
>UniRef50_UPI0000588046(148-411:414) PREDICTED: similar to RNA pseudouridylate synthase domain containing 4 n=1 Tax=Strongylocentrotus purpuratus RepID=UPI0000588046  E=1e-38 s/c=0.61 id=32% cov=65%
---VIFDKGDIIALDKPYGLPVHGGPGMKHSIDSLLPQLAWTLNnkgggntEELHLIHRLDKETTGVMLLARNERTARVLHEMFRKRQIIKRYLVITVGIPsPKEGILDMPMIEKEIDGKHRMVikpdmadlypdtigmrsgRKSRDSKEAITRYKVLSER-----------GNCALVQLEPETGVKHQIRVHLAQgLGCPILGDHKY-------------------------------------------------------------------------------
>UniRef50_B6HIT3(124-321:526) Pc21g01540 protein n=3 Tax=Trichocomaceae RepID=B6HIT3_PENCW   E=4e-38 s/c=0.81 id=30% cov=70%
---IIYEDDDLMVIDKPAGVPVHAAGRYNFNTVIQILRSERGSEWLPRPCNRLDRLTSGIMFIGKHAKGADKMAAALKARSVQKEYVARVKGKFPDgVVVCDQPIMQVSPKLG--LNRVRATGKEATTKFRRLayyppesaketesssddERPATPPASFANETEGYSIVHCLPLTGRTHQIRVHLQFLGHPISNDPIYSNRR---------------------------------------------------------------------------
>UniRef50_B8I5R6(76-267:303) Pseudouridine synthase n=2 Tax=Clostridium RepID=B8I5R6_CLOCE   E=4e-38 s/c=0.83 id=30% cov=73%
-FSVVYDDDNLLIVNKETGIPVHPDKNQKEATL--IDKLQSIYGPNLALCHRLDRNTSGLVIIAKNPATLEVMLEKIKNREIQKYYTCIVSGKMEKKN-AELVDYLEKNEKLSRVFINPEKTRNSVqiiTRYRILASMNSLN-----------LLEVELVTGRTHQIRAHLAYYGHPIIGDGKYGKNAENK----QYNAKYQLLCASRLTF----------------------------------------------------
>UniRef50_B8LC17(80-322:341) Putative uncharacterized protein (Fragment) n=1 Tax=Thalassiosira pseudonana CCMP1335 RepID=B8LC17_THAPS  E=9e-38 s/c=0.65 id=32% cov=92%
-VPVVYEDDHMAIVNKPSGVVLYRAEGGRGGGARDEDTPQNVPLKRPQPVHRLDRPTSGLVVVAKTKLAAVHLSQQFEFRKAEKTYVAIVNGIPRQSGVRAEPMQWNTIDY-------DLEEKTAVTRWRVLRKVKSLHGN----DGTLTLVEMKPKTGRYHQLRRHCAWVcNSPLVGDTTYDGGSEGALRLRKRG---LFLCSSEIALEHPHYNT--------PagqKEWVELKRNKQQLSFLQENEegRVIIRARIDLPDKFES
>UniRef50_B0SG87(81-320:320) Pseudouridine synthase n=2 Tax=Leptospira biflexa serovar Patoc RepID=B0SG87_LEPBA  E=1e-37 s/c=0.66 id=28% cov=87%
---ILKETEDFLFVEKPGNLPMHPAGRYRTKTLLSFLETKY---PKIIPVHRLDRETSGIVIFAKSEESRKWLQKKFETRVVYKEYFAIVLGKFTKEQKLDGFIGRDIHSVIRKKMifspVEFPDSKSCATHFVPILYNE---------DKKISLVLVKPITGRIHQIRASLLYLGFPIIGDKMYGlresifldfvNFGMTDSLKEELGFERQLLHAYSIRYLDDRGieNQMVHIHSKSFDEMDLYF--PNWKNYVP-------------------
>UniRef50_C9SGW9(214-419:549) DRAP deaminase n=2 Tax=Sordariomycetes RepID=C9SGW9_VERA1   E=1e-37 s/c=0.77 id=30% cov=70%
-IAVIHEDNDYLIVNKPAGVPVHPAGRYNFNSVVEILKSERGAHFMPRPCHRLDRLTSGILCFGKTAQAATDLSRQIQARMVRKEYVARVIGHFPDgEVVCDQPLLQISPRLG--LNRVRANGKFARTVFKRLAYYPPPlsdvdggpeqrpktpeeaadeEQRPWTAKKGYSIVRCLPLTGRTHQIRVHLQFLGYPIQNDPIYANQR---------------------------------------------------------------------------
>UniRef50_C5NYJ1(52-250:251) Pseudouridine synthase n=1 Tax=Gemella haemolysans ATCC 10379 RepID=C5NYJ1_9BACL  E=2e-36 s/c=0.78 id=24% cov=77%
-----YEDDYILVVSKPFGIKTHPNDIETENDTLVNYLIADY--SYLEPIHRLDIDTCGLVILAKTPLIKAKLDQMLEQRAIKRYYTALIKNNIK-PQTINTNIGRDSKEKNKMAVT--RNGKNAITNI---------LECSKLDQNRFS-VLISLETGRTHQIRVHLASIGVSIIGDKLYS--------KDGYKYDKMYLGALKVNFQHPVTGNTLEIKSSIEKDF---------------------------------
>UniRef50_C7RHE5(73-267:277) Pseudouridine synthase n=3 Tax=Anaerococcus RepID=C7RHE5_ANAPD   E=1e-35 s/c=0.78 id=24% cov=72%
-INIVYEDDNSLVISKEANITVNSKNQISLSNYIANYFIDSGQESKIRLVNRLDMDTSGLMLIAKNKYSHAYYQKQLEENTMKKKYLAVVEGMLDIDSLYEN---KFSYNEKKKNYEPSDKGKISRTYFKSIR-----------INCDFSIIECEILTGRTHQIRASLTDLGHPIWGDKLYGSDK---------NLDRFLLHSYRLEFT---------------------------------------------------
>UniRef50_Q0IBH1(25-218:220) Pseudouridine synthase n=11 Tax=Cyanobacteria RepID=Q0IBH1_SYNS3   E=2e-35 s/c=0.78 id=29% cov=75%
----------FLVVEKPSGLLSQPGLGDSQSDSLITRLQA--VRPELRLVHRLDRDTSGLLLLARDPESLKVLGGLFAERKVHKFYAADVHGHPKSRSGAVRLPLARLSAHPPRYG-PRRDGRSCLTLWR-----------CAQMGSDRSRLWLAPRTGRSHQLRAHLAAIGLPIIGDPIYASSGLGSPGE------RLHLHALGLSFSDPFSGQRIRVRSSLP------------------------------------
>UniRef50_A6DK57(8-218:218) Ribosomal large subunit pseudouridine synthase, RluD subfamily protein n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DK57_9BACT  E=3e-35 s/c=0.72 id=27% cov=79%
---IIYEKDGLLVLNKPYDLPS--TGRKLDDDDCLQYWLIQRQGAMVWAVHQLDADTSGINLFVTEKKLVKYYKELLEQAQADKQYLAIVHGVPSWKQCEEHGRIGKVDARSLGIHAE---GKTAHSHFEVIGSVK-----------DFSLIKVKIFTGRTHQIRIHLSHLGHPLVGEEWYCDPPCTAH-------QRQALHCYKVHL--PQT--AHTFSSPLAEDLKQLAQNHG-------------------------
>UniRef50_Q8IZ73(223-389:545) RNA pseudouridylate synthase domain-containing protein 2 n=20 Tax=Euteleostomi RepID=RUSD2_HUMAN  E=3e-35 s/c=0.90 id=30% cov=64%
-IRLLAENEDVVVVDKPSSIPVHPCGRFRHNT-VIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEvTCKEPILVVSYKVG--VCRVDPRGKPCETVFQRLSY-----------NGQSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIY-------------------------------------------------------------------------------
>UniRef50_P43930(3-185:224) Uncharacterized RNA pseudouridine synthase HI0042 n=15 Tax=Gammaproteobacteria RepID=Y042_HAEIN  E=4e-35 s/c=0.82 id=29% cov=71%
-IEVVYQHSDFIIINKSEGISVHKDQEEQGLTELVAKQLN---VPKVWLVHRLDKVTSGLLILALNAESAAEFSRLFSEHKIHKTYLALSNQKPKKKQGLIIGDMKKAREGAWKLCQTKDN--PAITRFESVSC-----------EPNLRLFILKPQTGKTHQLRVAMKSLGSPILGDGLYGKNTEK--------IDRTYLHATQLEF----------------------------------------------------
>UniRef50_A5FWV1(1-172:224) Pseudouridine synthase n=1 Tax=Acidiphilium cryptum JF-5 RepID=A5FWV1_ACICJ  E=4e-35 s/c=0.87 id=31% cov=66%
MIDpvILYHSTHLVVIDKPAGLPSHRGRGGGPSVEDWFPRWRRGAD-GPWLVHRLDADTAGCLAIARRKTTLVALQRAFAQRRVGKTYWAIVEGVPAAAHGTIELALARRTVPGGWRVAPDPRGDPAITDWRCLA-----------AGQGRALLELRPRTGRTHQLRVHCAESGFPIVGDPLYG------------------------------------------------------------------------------
>UniRef50_C7NFK5(86-313:316) Pseudouridine synthase n=1 Tax=Kytococcus sedentarius DSM 20547 RepID=C7NFK5_KYTSD  E=5e-35 s/c=0.66 id=36% cov=77%
-LPVLQADEHCVVVDKPPFLATIPRGVHVQQTVVA--RVREDFPEAV-PVHRLDRLTSGVLLCARTPEARRPLQQLFEKRQVAKTYEALVSLPPEEAAgafsvspgveglglaeRVERAIGEQEHHLVKKRgsqqVVVVPGPPNALTRIEVVEVDEA---------TGRARLRLFPHTGRTHQLRVQLAHLGLPIVGDPLYPVQTEQVTGDFSTPLQ---LLATRLEWTDPWTGK---------------------------------------------
>UniRef50_A7ZGA9(69-276:307) Pseudouridine synthase n=4 Tax=Campylobacter RepID=A7ZGA9_CAMC1   E=1e-34 s/c=0.72 id=28% cov=76%
-LKPIFECESFAVFDKPSGVLSHPNGRHCEYSLN--DEIYTLFGRDASVAHRLDCETSGVIVVGKDRNSTIKLKKIFENREVFKSYVAMVQGKIEREFTIDAKMdLANNYDDVKMRMQICENGKSAVTKILPIKYFD---------DIDTTLVRAIPLTGRQHQIRLHLFHVKHKILGEPLYGLSRPQiekildkemseRERINLTDAKRLLLHSDEISF----------------------------------------------------
>UniRef50_C4PLV8(72-273:274) Pseudouridine synthase n=13 Tax=Chlamydiaceae RepID=C4PLV8_CHLTZ   E=1e-34 s/c=0.74 id=30% cov=71%
----LWEDEHLCIYNKPA----------KQTSEDLAHQL------NVHLVHRLDRDTSGCILFAKHAKASSLITQLFKNPEIDKRYIALVFGQPRQESGIIttyTAPCYRRTGAVLFGNTDQNSGKITITKWEILTRY-----------PKYTLLLCRPVTGRTHQIRLHMKTIGHPIVGDVDYGNQEQPKNVV------RTLLHAASLAFISPFSNEKIEVSS---------------------------------------
>UniRef50_Q74Z98(105-287:381) AGR305Wp n=2 Tax=Saccharomycetaceae RepID=Q74Z98_ASHGO   E=3e-34 s/c=0.80 id=27% cov=65%
-LKVVFEDNDLLVIDKPCGIPIHPTAYFYKNTLT--EVLEDARGYPLFPCYRLDKITSGLLIFAKTQQTASRLQSQIRDQNMNKWYLARVDGNFDFNKKTASSPIYTFEPKKSLKGAFAP-VRDALTEFYHVAYNEELNQ---------SLVLCKPLTGRTHQIRIHLARLGHPIVNDPFY-------------------------------------------------------------------------------
>UniRef50_D2VTC2(412-619:624) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VTC2_NAEGR   E=8e-34 s/c=0.70 id=25% cov=78%
---ILFKNDEIIALNKPYGICVQGGSNQTFHIDALLDALTglDGFNVRPKLVHRLDRDTTGVLIVARNRAGAIRMQQWLQESTVplKKCYWAVTVGVPTPTTGRIKMVIDIQKDANGVEKVVPVDNKTDSSKISVSEYKTID-----HMTDKLAWVALYPVTGRKHQLRVHCAsALGAPILGDYKYGEGVPESLTHvvPDKSLKRLHLHHRAMKLP---------------------------------------------------
>UniRef50_C5K6J4(121-385:393) Ribosomal pseudouridine synthase, putative n=2 Tax=Perkinsus marinus ATCC 50983 RepID=C5K6J4_9ALVE  E=4e-33 s/c=0.54 id=32% cov=70%
-LKIVGETDDVVAVDKPSGMPVHSGGGHRVNCLSAILKEQDPsrFSLAIHTLHRLDRLTSGIVILGKNPDVARAFSEAFKKHdqEIQKCYLARVKGKFEGSNVVVEGFMRCVDFRVGKFIlvksnkgtaSEDANQGDAPTstpsgddksaveeeHIEDKWSQTSFDKVWYDEQNDETIIKCYPKTGRTHQIRVHLESIGHPIANDSCYGG-----------------------------------------------------------------------------
>UniRef50_C0B9T1(2-161:172) Pseudouridine synthase n=2 Tax=Clostridiales RepID=C0B9T1_9FIRM   E=5e-33 s/c=0.89 id=32% cov=62%
-------------------------------------------------IHRLDQPVSGILVFARTPAAAKNLNQQLQNDQFEKYYQAVVCGSLPDSGTLTDYLVKDGRTNTSRICsKNTPGAKKAVLSYEILETSEV---------TGLSVVQIHLGTGRHHQIRVQMAGAGAPLWGDNKY-----NPEFVNKRGYFPIALRAFRLSFCHPTTGKRMEFEVP--------------------------------------
>UniRef50_Q6CG33(109-326:337) YALI0B01276p n=1 Tax=Yarrowia lipolytica RepID=Q6CG33_YARLI   E=9e-33 s/c=0.65 id=31% cov=63%
-IRIVFENDALVVVDKPGGIPVHPTGKYLFNSVKEILKHETGL-EELYPAHRLDKNTTGVLVFAKTSESVNHVTQQIMSRSAKKEYLARVKGRFPPGRVETHHPVVENTIKRNVQ------PKDAHTAFERVAYDEHR---------DLSIVRCLPSTGRNHQIRQHLLHLGYPIENDREY-------------------------------------------------------------------------------
>UniRef50_Q6A5E7(78-289:295) Pseudouridine synthase n=4 Tax=Actinomycetales RepID=Q6A5E7_PROAC   E=1e-32 s/c=0.67 id=29% cov=79%
---ILYSDERILVVDKPHFLSSIPRGRHVLESVVVRLRTQLGL-PELTVAHRLDRVTAGVLLLTRERKWRRPYQEIFERREVVKKYRLVAPVVHDPAGEGVTAtksgwqvRSRIIKERGILQAREVPGVPNAVTDIALI-----------GEHGGWGLYEASPRTGRTHQIRLHMQRLGAPIVNDPFYPVVLDTPVDDFTHPLQ---LQAWRMGFTDPVTGDPRAFTSRL-------------------------------------
>UniRef50_Q07X80(109-321:326) Pseudouridine synthase n=17 Tax=Alteromonadales RepID=Q07X80_SHEFN   E=5e-32 s/c=0.66 id=30% cov=75%
---VLYQDNDTIIVYKPHFLPVTPGGNYVNECLVHRLRIATQIDT-VAPAHRLDKDTAGVMLMTLNPQTRHAYHQLFLDDKITKDYQAIAKLTPTllsefADNTCMLPIHWTVKNRivaanPSFTMQVVEGEANSHSEISLVAV-----------KNGFGLFELSPITGKTHQLRVHMQSLGMPILHDRFYPVLLPKGPDNFDKPLQ---LLAKRLRFTDPIS-----------------------------------------------
>UniRef50_C8RQ24(59-294:297) Pseudouridylate synthase n=2 Tax=Corynebacterium jeikeium RepID=C8RQ24_CORJE  E=5e-32 s/c=0.59 id=27% cov=88%
-IPVLYSGSDAVVVDKPHGLPSTPNGRLLRATAQSLMRVRLQ-EPELVAAHRLDRDTRGLLVLARNPVTRGFLQTQFQRREVSKTYQALAADIPEIGSQWQDvqLPMLKIKDDPQVKVVDGERSRLTVTRIRKLASSagaEARPVEATRAGTPTAVYELQPLTGYTHQLRVLMNHLGAPIYGDDTYPEYRPGA------GALRLRAVAIELALVASLKNrQRIEIERCLEDPWAQWGNWPSWR-----------------------
>UniRef50_P75230(87-322:326) Uncharacterized RNA pseudouridine synthase MG370 homolog n=4 Tax=Mycoplasma RepID=Y548_MYCPN  E=6e-32 s/c=0.59 id=21% cov=75%
-LQVIFEDEQLIVVDKPAGVVCQPDAKHELFNLANSLLKHCGYNQYfknslsfiPRFAHRIDRNTCGLVIGAKTNQALQELEAVFRHNLLMKQYQGLVFGPFNFKGTQKAYWAKDAyQALVTVKAKPFPNAKPITTIFE---------NSKYLTKLDLSLLTIRLVSGKTHQIRACLNLLNTQLVGDRKY---QLLQFKNRNRDFKHQALHATNLSF----------------------------------------------------
>UniRef50_C0QC81(75-291:295) Pseudouridine synthase n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0QC81_DESAH  E=6e-32 s/c=0.65 id=32% cov=71%
---------------KPSGMSVHNHPGSDLLCVLerqiradedLMVALGAQEGFQIHPVHRLDQETSGLILVATDPDRLRYLSNLFQQGAVQKHYIALVHGNFDPPCDPFQVWDTPLSKQAGGRTDPRGKGKrvRSETRYRIMDQ-----------SPHYTLLEIELVTGRKHQIRRHAKLAGHPVTGDTRYGSKRSVEFLRENHAYDRLGLHSFKIEFI---------------------------------------------------
>UniRef50_B7FVV1(208-424:424) Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FVV1_PHATR  E=6e-31 s/c=0.63 id=29% cov=68%
-LPVIIEDDHWALVNKPAGIVVYNQRNGGHGIMTVRAALPFVLAPpkvgtisvlrRPASVHRLDKPTSGILCIAKTKPAMLCLSRQFHDRIVKKTYFAVINGIPTYSNEskissktaYELGVDVDPNDLDDWQLIDSPlDEKKAVTVWRVVRSIKSLHANDGY----LTLVELKPKTGRYHQLRRHMAWVcQRPLVGDDEY-------------------------------------------------------------------------------
>UniRef50_A6VWM4(1-207:223) Pseudouridine synthase n=2 Tax=Marinomonas RepID=A6VWM4_MARMS   E=7e-31 s/c=0.66 id=27% cov=70%
MLQILFRSVDYWIVEKPAGMSFHA---ESEGLGVMQTLAISYPDQNFYPVHRLDKMTSGLLIVACHAAAAAEFGKMFERHEMEKRYLALSAKKPKKKQGTISGGMAPSRRGQWKLTQDNEN--FAVTQF------------FSSAFHGLRVFIVRPLTGKTHQIRVALKSLGSPILGDLRYSGE----------GADRGYLHAYSLQF----------------------------------------------------
>UniRef50_C4XWV4(146-316:432) Putative uncharacterized protein n=1 Tax=Clavispora lusitaniae ATCC 42720 RepID=C4XWV4_CLAL4  E=1e-30 s/c=0.79 id=29% cov=64%
---VLYEDENILVVNKPAGVPTHPNGIFRRNSLT--EIVRFELGVSVYPCHRLDKGTSGVLVLAKT-KTGKMLQEvlQNKKSHVEKWYVARVRGKFPFASCSYTSPVFSINTAGTGYLNIPNAERvpaTSSTHFKMVSY---------SPELDESIVFCRPISGKMHQIRVHLRNMGYPISNDPLY-------------------------------------------------------------------------------
>UniRef50_C8PQZ0(7-266:276) Pseudouridine synthase n=1 Tax=Treponema vincentii ATCC 35580 RepID=C8PQZ0_9SPIO  E=2e-30 s/c=0.52 id=23% cov=92%
---IYFEDDYCAVVYK----------LNGENAQTFFTPLFPH-KPFIAPINRLDTPVSGIILLAFSAQAQTLLSQAFKTGSVEKEYWAICERTAADTTEEEPGIHRLEHWLGFHTKTQKAFVGAAPIDITLTNTTAAGITKPKKhkkpalkkavlywtlcgKGDRYDFIRISPETGRTHQIRVQMAAAGHPIKGDLKYGARRSETGGGIR-------LHSYKLSFSHPVTHQDITVQAPPiqPDTlWKACMAACTNSTTFSNKGEADAGADTTAPATLPT
>UniRef50_B8P9A9(86-272:448) Predicted protein (Fragment) n=3 Tax=Agaricomycotina RepID=B8P9A9_POSPM  E=2e-30 s/c=0.72 id=31% cov=65%
-VRIIHHDreREFIIIDKPGSIPVHASGRFFRNSLVEILK-NDFGFKKVYTINRLDRLTSGLMIIPLSSSMANTLTQEFAAGTIRKEYIARCRGQFPEEELACEVPLLTIDRQM-GLNVVHPEGKPAKTIFKRMHY---------DANTDTSVVHCEPLTGRSHQIRVHLQYLGHPVANDPIY-------------------------------------------------------------------------------
>UniRef50_UPI00005230E6(163-430:494) PREDICTED: similar to RNA pseudouridylate synthase domain containing 4 n=1 Tax=Ciona intestinalis RepID=UPI00005230E6  E=3e-30 s/c=0.50 id=31% cov=65%
--NVIYADNKLVIFNKPYGLPMHDGDGTKQTVKNVLPFLSKmvygiNTDIPLHLCHRLDKNTTGITICSTDAEMADYVMGLFRQRRVLRKYLAVVVGEPEPMkgvvdmpmsesivsatkstkrhsRMIIKPDVRYDDATGKEYPLRNAGGHTAITHYRTIDT-----------TGDLSLVELQPQTTVKHQLRVHMAdGLSCPILGDHKY-------------------------------------------------------------------------------
>UniRef50_A0YDZ6(85-261:280) Pseudouridine synthase n=1 Tax=marine gamma proteobacterium HTCC2143 RepID=A0YDZ6_9GAMM  E=2e-29 s/c=0.74 id=27% cov=65%
---------------KPYGVLCQGSKWGDHCTIDRMIEI--YTQKRSYLVHRLDRATTGLMIIAHSKDMAAKLSKLFRDRAIDKRYLAIVDGDFPYC-------------EKKQTITSTLDGKKAISHMRRLRYSQR---------HHQSLIDVNIETGRKHQIRRQLSDQGYPIVGDRLYNPAGDDKQHTADLK-----LCCYSLGFKCPIT-----------------------------------------------
>UniRef50_Q5DDR8(132-316:438) SJCHGC01065 protein n=3 Tax=Schistosoma RepID=Q5DDR8_SCHJA   E=2e-29 s/c=0.71 id=26% cov=66%
-IEFIHDSHDMLVINKPPSIPIHPCGRYTLNSITHILA-KDYGLRPLRFTHRLDRMTSGLLLIAKDYDTSVRLQSQIASKEVTKHYICHVDGCFPTEPIDHCTGFEINNGvvvcsqpvgpispkmGIHAVLPESAGGKPARTHFLRLNYNSV---------TNTSLVICRLFTGRTHQIRIHTQYLGYPIVEDPIY-------------------------------------------------------------------------------
>UniRef50_A1U1A1(90-263:267) Pseudouridine synthase n=2 Tax=Marinobacter RepID=A1U1A1_MARAV   E=4e-29 s/c=0.75 id=28% cov=66%
---------------KPHGLLSQGSQWGDHCSL--LRLAEIELNTPCFLVHRLDADAAGLMLIAHDGKAAAALSELFAGRAMTKIYRARVAGNLMADDLRLDTPL---------------DGKDSISRVTTLSRDE---------DSDTTDVQVRIETGRKHQIRRHLAGIGHPIVGDRLYGTASAA----------GLQLTAVELAFRCPVTRKAQVFRLP--------------------------------------
>UniRef50_Q7PQ70(52-282:300) AGAP004401-PA n=4 Tax=Culicidae RepID=Q7PQ70_ANOGA   E=6e-29 s/c=0.56 id=28% cov=84%
-VDVLYTSGNFLVINKKHDLLINSNDTKKKTVQTIMRkqfpeYVQDNLTHDFYFAHRLDFATSGILCIPLNKNACKEVCQVFEEQRARKYYLALLRGHTDFDEEVIDiaigEDVRFKDTSKKMCTILEDelcqNPRRSITKVLVLDR-------GYYNGKPVTKVLLRPITGRRHQLRLHCSQIGHVIVGDYTYSLKIDTSP-------PRMFLHAFRLVL--PNTIENLDIQTDDP--FTEKALKYKWK-----------------------
>UniRef50_Q1MQF8(102-298:321) Pseudouridine synthase n=2 Tax=Bacteria RepID=Q1MQF8_LAWIP   E=1e-28 s/c=0.65 id=28% cov=69%
----------FIIFYKPAGLAVHGGTGQTDSLAHRLSQHYAHSTFMPTPVHRLDKDTSGLLLVAKTYNSLRYFSELFASHstQLTKEYLAWVVGICPWTQPICLEDILTKKQKQDNYSRlnsyqnklQQTSAQKASLTVRCIKQYK-----------DKSLLLIKLHTGRTHQIRIQLSIHGFPIIGDKKYGN---------TIRSHNLKLHAFRLSFP---------------------------------------------------
>UniRef50_B9L6B7(60-239:253) Pseudouridine synthase n=1 Tax=Nautilia profundicola AmH RepID=B9L6B7_NAUPA  E=1e-28 s/c=0.72 id=28% cov=70%
----IFEDKNLLAVDKPPYITS--------------EEIAKNFGYEL--LHRLDKETSGVLILVKNDEFKKKAIEEFKKQNVYKEYITWVSGIVAEPMKIDLPI-KVIKTKSGALAKISKDGEDAVTEIEPILAFRTK-----------SKVKAVIHTGRTHQIRAHLKAVEHPILGDEKYGGE----------PFKRVMLHHHKFKIFD------YNFTSPEPSDFK--------------------------------
>UniRef50_Q2BL24(81-291:313) Pseudouridine synthase n=1 Tax=Neptuniibacter caesariensis RepID=Q2BL24_9GAMM  E=1e-27 s/c=0.60 id=30% cov=64%
----VWESDELMAINKPPLLPVSRTTRNLYMTLISLVRRQTPY-PDAQLLHRLDTETSGLILLAKNREADRKWKPQLAKLIRRKVYQAWVHGSPNWDHLLMECELseKAGSDIRSQVYVVEPqsdsqylKPRPSKTEFLVLQR-----------AGSKSLIQCELFTGRKHQIRAQLAHLGHPIIGDKIY-------------------------------------------------------------------------------
>UniRef50_Q14NQ9(91-277:312) Hypothetical rna pseudouridylate synthase c protein n=1 Tax=Spiroplasma citri RepID=Q14NQ9_SPICI  E=2e-26 s/c=0.65 id=26% cov=68%
-LQVVYEDDNILVVDKPHGVEMY-SKFHTSLDAMVQHYLiqkheyhpEDEQSFVISHVHRLDKLTRGLVLYAKNKITLDLLLAKINQKEsIEKKYLAKCEGIIKETDFTLTGYLYKNEDKQKMVftKTVQPHAKVVKTHFRV-----------QHQLTNATWLEVTLITGRKHQIRASLSYLHHPIVNDIKYGAKQETK------------------------------------------------------------------------
>UniRef50_C9N1D6(104-315:328) Pseudouridine synthase n=1 Tax=Leptotrichia hofstadii F0254 RepID=C9N1D6_9FUSO  E=7e-26 s/c=0.57 id=22% cov=75%
---VIFENDDFFIVNKKEKVPMHKGTGHKYGLAEVFKKI--YKSDNINFANRLDFETSGLVIGCKTLKFLRYISQKIRDNEVHKKYFAVVHNKNIIRrnklerekfnledFKIENYLTTLENKVIVSENPVSRESKKSITYFKhvnfnKLKKSKEILKLFEKNNKNILLLDVELITGRKHQIRAQLAHESLFIVGDKKYG---------IKDGSDRFFLCCYSISF----------------------------------------------------
>UniRef50_B2RHT4(87-304:324) Probable RNA pseudouridylate synthase n=1 Tax=Porphyromonas gingivalis ATCC 33277 RepID=B2RHT4_PORG3  E=9e-26 s/c=0.55 id=23% cov=82%
LVRIIWQDDYFVLIEKKAGVSTVASGVNKDRTALRIvsdHLKQYDPEVKIFMLNRLDKDSAGMVLFAKNKEVQGFVVDKWSKVVLEQRFVmAIEGEMPDAEGTLDPPRYQTSIKGKQSRIVAETPSVHSVgtARYKVIRRGAV-----------CSLVEVTLLSGRNNQLRRQMGQLGIPIAGD--------WRQGSSFRHLDCLALQGTRFVFRHPETGDTQEYKLPLPKLFRRLI-----------------------------
>UniRef50_B3L648(66-243:504) Ribosomal large subunit pseudouridylate synthase, putative n=6 Tax=Plasmodium RepID=B3L648_PLAKH  E=4e-25 s/c=0.66 id=26% cov=67%
-LSIIYENEFFLVVNKPYDIKLEKGKLDDVYPSVETLLRQKTNLDVFRICGQLDYATSGLLIIAKDKLSCNILNYNIESKRISKIYLAILYGHLPLGVLHvNTPISKIKNNFKMKLCYNYNDyydtGKYC---YSLI----YPYKQCYLKNQKVTLCELRTITGRRHQLRLHALCLGSGIVGDETY-------------------------------------------------------------------------------
>UniRef50_A9UZH2(118-333:512) Predicted protein n=1 Tax=Monosiga brevicollis RepID=A9UZH2_MONBE   E=5e-25 s/c=0.54 id=28% cov=74%
-------DPFVWVVNKWAGLVTQGEKDGQSLAAYLKYMRMRHDDdmrlltRPLSLVHRLDRNTTGVSFIARNPVVHALLQDVLATHQAQKIYYATTLGVPfPRKGEIKGYLTPHKNGVKLDATPQNKNSVFSHTRYQVVDALDR----------EAALVRLEPVTGRRHQLRAHLAQgLRTPILGDTQYGVGCSNALRPLLFPTKGrpstkvvveglpMMLHAFELVIP---------------------------------------------------
>UniRef50_D2VN10(126-309:314) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VN10_NAEGR   E=3e-24 s/c=0.62 id=25% cov=60%
-LNILFEDDFLIVLDKPKFMTVHPSlkpkPRNTTGTLVNALLFHTNGKLstcgsceehyRPGIVHRLDRDTSGIMVVAKDDETHLALKKLFENKnvgdennedKITRYYQALVENELNQSEGRIEIYIKRHHSMPSKREVTnnalETGAKLSITEYKEQKTFPVNNLTGCKV---LTLVRCKLLTG-----------------------------------------------------------------------------------------------------
>UniRef50_C4XKF0(88-262:290) Putative pseudouridine synthase n=1 Tax=Desulfovibrio magneticus RS-1 RepID=C4XKF0_DESMR  E=4e-24 s/c=0.65 id=27% cov=67%
---------DYVLLNKPSGL--HSAALAQGGGESVEALLPDIFPGRPsFLLSRLDSLTTGLLPAAFSPEAAATYRDMEESGEVDKTYLAVGHGEPDVTYFRCDGELDAADRKKTRVLDRATIDSLRMTEVEALETR-----------GGVTLFRCTIKKGARHQIRTHLAWAGHPLVGDPLYGQGEGE----------RLFLHCA--------------------------------------------------------
>UniRef50_UPI0001903DB3(49-173:303) RNA-pseudouridine synthase protein, ribosomal large subunit C n=1 Tax=Rhizobium etli 8C-3 RepID=UPI0001903DB3  E=2e-23 s/c=0.89 id=27% cov=48%
---VLHEDEKVIVLNKPPGIAVQGGSGVARHIDQMLEAWTSPKGEKPRLVHRLDRDTSGVLVIARTRGAAQKLTAAFRERDTKKTYWALVKGVPrKHEDKISTWLVKEATADGDRMRIAKTRRKTAPT-------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4S6L3(42-210:213) Predicted protein n=2 Tax=Ostreococcus RepID=A4S6L3_OSTLU   E=3e-21 s/c=0.62 id=35% cov=45%
---------------------------------------------RPRPVHRLDELTGGLLVCAKTRMAMTALSAAFEKREVRKRYRAVLRGRVES---------------KKGVVDVPLGGLEALTEYSVVREYESEEYGGI-----LTLIDFFPKTGRTHQLRRHAKALCAPILGDVKY-------------------------------------------------------------------------------
>UniRef50_C1EC23(120-312:498) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1EC23_9CHLO   E=6e-21 s/c=0.53 id=28% cov=65%
---VLLEDSKLVFVDKPAGVPTLAGCGPKlqgENNATRLLNRTRAENAtgaddgELFAVNRIDKPVSGVWILAKgSRLAARCRAALAKPGHETKTYLARVRGAVVGPIRIDAPLSVGAD--GRATTSGGADAKPAVTLVHPVARYPPPW-------DDCTLVACRLErSGRFHQIRCHLASVGVPIANDATY-------------------------------------------------------------------------------
>UniRef50_B3L0N6(22-277:392) Putative uncharacterized protein n=3 Tax=Plasmodium RepID=B3L0N6_PLAKH  E=2e-20 s/c=0.39 id=18% cov=87%
---VLYQDDDYLVVNKAYGVSTFGRAPQKESIIKSLEELNLEGHESANVLYKLHNHVGGCLLICKNKF--------IKNHTYGNTFLALVYGQVENAQNVKVKLGlKYLPNSGIMIPSNDQN------HLRDLKSIKYDVISNtiSYETHKFSLLKIHTAAKDAKFIKPLvFYSLYTCIVGDNEYvggwrkliknGFFAYRDVGGQVERANRlllkklphmgknnelmLHLHCLTVTFQSACS-RVVSVSSPLPRHMRETLNFLGAPSLSQTIE----------------
>UniRef50_B9Q0D6(257-567:713) Putative uncharacterized protein n=1 Tax=Toxoplasma gondii GT1 RepID=B9Q0D6_TOXGO  E=2e-20 s/c=0.32 id=25% cov=86%
----------------------------------LLHQLRFSMDETPKLLHRLGKEVTGVLLLGRTKQTAQVAVDRLRGGTFGVlTFFALLHGRPPggRREGVIRIPLAENEAGVMVPTAVQRGGSVSVTRWKLLKvaspqTRDVKGDAEQSHACGFSLVELEIrHQQCRHQARAHCLYgLSCPIVGDRVYGPltsrwrqlastgaasftsedrvsatagtarlsvrndagdasahaatdeETRNRVAAKSEEKRRlaearatlgvtapsmLHLHSRAISFE-TFAGRPVRIQAPLPPHMRQAASRLGWEFFVEQLDAnlSPLTADMGIDEE---
>UniRef50_A6GFD8(92-396:401) Pseudouridine synthase, RluD n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6GFD8_9DELT  E=1e-19 s/c=0.33 id=28% cov=71%
-LEVLAETPDFVYVHKPAGVHTVAlTPQQPGVLATAVAERwpecagASEDPREGGAVHRLDRPTSGVVAFARSPEIWARARKAFSAEQVRKRYLAVCldLGARERGAAMTWPPALPEGGLRGWVlpaeveahpraelgslagidtatathpsfrvraplgRVAREAEIPSHTAVRLDGQRASSVVHPLAQASATStgaqpwLLALELETGRRHQARCHLAWIGLPIVGDSLYGPR----------------------------------------------------------------------------
>UniRef50_O96199(27-306:450) Conserved Plasmodium protein n=1 Tax=Plasmodium falciparum 3D7 RepID=O96199_PLAF7  E=1e-18 s/c=0.34 id=17% cov=84%
--NILYCDDDYLVVNKKYGMFTFGTSRNKESVLKNLSLLNEDEGKGWNILYKLYSQISGCVLICKNK--------IIKYNSYDNIFLTLVYGKIEnvknmkeknyYYNEIKLYLKYLPESNIMITTNNYEDiNKMKCLKYEVL------NNNIYYQKHNFSLLKLYINACNSQYIKPLLYYSLHtCIVGDNEYinvhkkilqkkknekyiikkepyllynnnnNDHVPNILKSRKFLLKklnkekqgnelKLHLHCLNVTFQYQC-NKIKSICAPVPSHFKDTLHILG-------------------------
>UniRef50_C1DZS3(156-445:474) Predicted protein n=1 Tax=Micromonas sp. RCC299 RepID=C1DZS3_9CHLO   E=2e-18 s/c=0.33 id=27% cov=79%
---IIARGRDWVAVDKPPGVPAGPSLDNATECATyrVARALRRLEttdnddddddeeeedeekkkkkkeeeegghswwggdgdgdgdgGTTLTTTHRLDVATSGVLVLARRSSFAAEFNDALRRRRVTKTYecvtaRAVPVGVLEHWTEessgaregPARFEMRELEPGDPRWRDVAADGKYSDDAFvtpdgrklcvlRVLGCEETEGLTKRltkrlageageaGEASRAYVSTIELVTGRTHQIRAQLSAIGCPILGDVLYGGVDLSREGGATPRVlrddDRLCLHAAEMR-----------------------------------------------------
>UniRef50_C5DSY2(5-202:250) ZYRO0C03894p n=2 Tax=Saccharomycetaceae RepID=C5DSY2_ZYGRO   E=2e-17 s/c=0.46 id=27% cov=66%
VLKIVHECNNYFLINKPPNVLSQPGNVHRWiyhglyknqhvNTPkVLLDELKSQSStskrdfDSWRLVHRLDSCVSGGLLVATNKNAAKYFSRNLKEggnkgYKIDRRYVA-----------MIDNPGKGDPKYLNEYGIIDKMG--MVSKYRRFDEKC---------------ILVELSTGQKHQIRKHLSHIlKQPVLNDVKYGG-----PLLPHTDPLQIALHAA--------------------------------------------------------
>UniRef50_B4U4Q4(72-224:266) Pseudouridine synthase n=15 Tax=Lactobacillales RepID=B4U4Q4_STREM   E=1e-16 s/c=0.59 id=27% cov=52%
-------------LNKPRGVIS--SVSDDKGRQTVIDLL-PQVKERIYPVGRLDWDTSGLLILTNDGDFTDKMIH--PRNEIDKVYLARVKGVVTK---------ESLRPLTRGVVIDGKKTKPA--RYRIIRV---------EPDKNRSIVELTIHEGRHHQVKKMFEAVGH---------------------------------------------------------------------------------------
>UniRef50_A4QE19(138-282:320) Pseudouridine synthase n=13 Tax=Corynebacterineae RepID=A4QE19_CORGB  E=1e-16 s/c=0.62 id=30% cov=55%
------EDLEYFVLNKPRGM--HSTMSDELGRPCVGDLVSEKtaSGQRLFHVGRLDADTEGLLLLTNDGELANRLMH--PKYEVSKTYLATVRGEATNKLVSALRDGVELEDG------------PAKADF----------AQIIDVFQGKSLLRIEIHEGRKHIVRRLFDELGFPV-------------------------------------------------------------------------------------
>UniRef50_UPI0001693918(64-203:249) pseudouridylate synthase n=1 Tax=Paenibacillus larvae subsp. larvae BRL-230010 RepID=UPI0001693918  E=1e-15 s/c=0.61 id=26% cov=54%
-----------ILFNKPKGVIT--SVSDPEGRRVVGDFLK-GIKERVYPVGRLDYDTEGLLILTNDGEFANMVTH--PRHHVSKTYHATVKGVP---------HGSVLEKLREGVKLEDGMTAPAEVEYHDID-----------PDKKQSVISITIYEGKNRQVRRMFEAVGYPV-------------------------------------------------------------------------------------
>UniRef50_Q9CKK7(51-200:241) Ribosomal large subunit pseudouridine synthase E n=61 Tax=Bacteria RepID=RLUE_PASMU  E=3e-15 s/c=0.57 id=22% cov=57%
----------VILFNKPYDVLTQFSDEEGRATLKAFI-----PIPHVYPAGRLDRDSEGLVLLTNNGEIQHRL--AVPKFNTEKTYFAQVEGIPQETDLAQL-----------RQGVVLNDGKTLPAKVRLVpepnWLWQRNPPIRERKQIPTSWLEIKIHEGRNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_D2V6I3(132-229:279) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2V6I3_NAEGR   E=3e-15 s/c=0.86 id=32% cov=37%
-LEIIKEENDFVVVTKPPGICVHPIKRYHKNSLFYMleheYAHHFGNDLHCKTIHRLDKETCGVLIVGKTSEGAKYFQKLLKEKQVEKQYIARVDGIVK---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5KLG0(62-228:261) Pseudouridine synthase n=8 Tax=Bacteria RepID=A5KLG0_9FIRM   E=5e-15 s/c=0.50 id=22% cov=58%
-------------LNKPAGVVS--ATEDKKER-TVIDLIKESKRKDLFPAGRLDKDTEGLLLITNDGQLAHRLLS--PKKHVDKIYYAKIKGIVTEEDVRLFEKGVHIGDEKPTMpaaleilSVQKERRKEKIKEQKILPETKNET---DEKEDGYSEIYLTIKEGRFHQVKRMFRAVG----------------------------------------------------------------------------------------
>UniRef50_Q9U190(1168-1446:1469) Possible RNA pseudouridylate synthase n=3 Tax=Leishmania RepID=Q9U190_LEIMA  E=2e-14 s/c=0.29 id=25% cov=68%
-----------------------------------------------GLVNRVDVGTSGVVLVARTADAlHGAADAMIREHHMRKTYRALVQRWPPFSSSSSSSAstvrydddnaaaaplfsvspflspmpsavvcapvyaaGATASSISRRSALPLSHGrqlqspgqpsadalaasragstlswsssvpvslsslehvhqqyatlhaalqdqRNAITRYRVLEYF---------ASAGVAYVQVELCSGRRHQIRQHFAQLGFPLVGDARYHAGVVAGHAGTTLGMRRAALHAYTVDILATTDGddlasseevpDRVVVQAALPADMHRAL-----------------------------
>UniRef50_A9GX03(64-201:399) Pseudouridine synthase n=2 Tax=Bacteria RepID=A9GX03_SORC5   E=2e-14 s/c=0.59 id=25% cov=50%
-----------VALHKPRNVVS--TLRDPEGRPTVADHVR-GTGARLYPVGRLDFATSGILLMTNDGDFANALLH--PRGGVPKTYVLKVQGVMS-----------DDDLTPWREGIRLEDGVTLPAEARLLRH-----------EGDKTWLEVTLREGRNQQIRR----------------------------------------------------------------------------------------------
>UniRef50_Q87QY8(63-232:238) Ribosomal large subunit pseudouridine synthase E n=244 Tax=Bacteria RepID=RLUE_VIBPA  E=2e-14 s/c=0.48 id=22% cov=58%
----------VIIFNKPYDTLSQFTDGDGRKTLADYI-----PVKDVYAAGRLDRDSEGLMVLTNDGILQAKLTQ--PKSKSPKTYWVQVDGAPQEQDLEKLRKGVELKDGMTLPAKVEVI--DAPTIW------ERNPPVRFRANIPTTWLAITIIEGRNRQVRRMTAHIGFP--------------------------------------------------------------------------------------
>UniRef50_Q38VQ0(53-197:239) Pseudouridine synthase n=6 Tax=Lactobacillus RepID=Q38VQ0_LACSS   E=3e-14 s/c=0.56 id=25% cov=56%
--PIRYQTNFYWLLNKPAGVIS--ATTDPQKT-VMDLFAPADYREDLFPVGRLDKDTTGLLLITNDGDLAHDLLS--PKKHVAKTYRAKIAGVVTAADQAQFAAGLKLR---------DFDAQPAQ--LTILRTDTARQE---------SLIEVEIHEGKFHQVKRMFHAVG----------------------------------------------------------------------------------------
>UniRef50_B9E1X9(71-227:245) Pseudouridine synthase n=39 Tax=Clostridium RepID=B9E1X9_CLOK1   E=7e-14 s/c=0.51 id=24% cov=57%
-----------ILLNKPRGYIS--SVKDDRGRKTLLDIVK--VNERVYPIGRLDYNTSGAIILTNDGEVYNNIAHPGSNKS--KIYIAAIKGIPSSEEIKRFENGIDIGGYI-----------TAKAKFDFISSNKES-----------SKVKIEIHEGKNRQVRKMCDAIGHPVitlmriaIGDIKLGNLKE--------------------------------------------------------------------------
>UniRef50_C5CGJ5(29-171:205) Pseudouridine synthase n=1 Tax=Kosmotoga olearia TBF 19.5.1 RepID=C5CGJ5_KOSOT  E=8e-14 s/c=0.56 id=33% cov=32%
---VVY------ALNKPRGYLS--SMSDDRGRKTIADLIKGKIPEKVFHVGRLDMDTEGLIILTNDGELARKLSH--PSSKIRKTYVARVTGKL----------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0W634(12-287:493) Ribosomal pseudouridine synthase n=1 Tax=Culex quinquefasciatus RepID=B0W634_CULQU  E=1e-13 s/c=0.29 id=29% cov=57%
---------------------VHPCGRYRHNT-VVFILAKEYNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEHQIRNRQVQKEYICRVEGEFPesspvsnsanhpaaapaqqqrehtssrssrgkrrrssprtallvvaarhqakhEDEERERTLGGDPSPHRPvkkggslnhhtrtaensltsnalprskrclvagggtaddellgmgsntldgiieckepievvsykiGVCKVSPKGKECTTTFQKLGY-----------NGSSSVVLCKPLTGRMHQIRVHLQYLGYPVVNDPLY-------------------------------------------------------------------------------
>UniRef50_A4BDP6(4-153:228) Pseudouridine synthase n=1 Tax=Reinekea blandensis MED297 RepID=A4BDP6_9GAMM  E=1e-12 s/c=0.51 id=25% cov=58%
-----------LLFNKPFQVLTQFT--DPDNRQTLADFI---DVPEVYSAGRLDYDSEGLLLLTDDGALIHSMMN--PRFKTPKTYLAQVEGDITDEAIRRLESGLQLKDGPTLPAKARRVSEPAWLWPR-------QPPIRERATIPASWVELTLVEGRNRQVRRMTAAVGFP--------------------------------------------------------------------------------------
>UniRef50_Q4TBL2(11-172:220) Chromosome undetermined SCAF7118, whole genome shotgun sequence. (Fragment) n=1 Tax=Tetraodon nigroviridis RepID=Q4TBL2_TETNG  E=1e-12 s/c=0.47 id=23% cov=58%
-LRVLYHSHDYVVVDKHWDLRI--DSKMWYEKLTVQAQLQASFPPAGRPQHLLRFQV--LSPVGFLDKWSSLCCPQQSCCWPG------------------VPLLQGPHRHQSLPRLSCEKPKTCRSELAVLEY-------GLYDGEPVTKALLQPLTGRTHQLRVHCSAIGHPIVGDVTY-------------------------------------------------------------------------------
>UniRef50_B8J2T9(240-407:493) Pseudouridine synthase n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 RepID=B8J2T9_DESDA  E=2e-12 s/c=0.45 id=27% cov=50%
---------------------------------------------------RLDFGTSGLLCAALSTSAAEDFRAAEAAGLCEKRYVALLSGVLSGPVVARQEL--DVSKRRKSRVLPALAHHTRWTEFWPLHVWRPGDVSVQAlqallgpagggapendapvvtpeagglpvPAAGLTLAACRIRRGARHQIRAHAAGLGHPLWGDSLY-------------------------------------------------------------------------------
>UniRef50_B7L2Z9(86-225:320) Pseudouridine synthase n=4 Tax=Rhizobiales RepID=B7L2Z9_METC4   E=3e-12 s/c=0.53 id=21% cov=51%
-----------LLLNKPRGLLT--TYGDPQGRKTVYDCLAGHDLPFLAPVGRLDCASEGLLLMTNDTRWAHRLLD--PASNVDKVYHVQIDRRPDEALLTGLREGVAHDG----------------------ERLAAKSVAPLRVGERNAWLEVVLSEGRNRQIRRMMA-------------------------------------------------------------------------------------------
>UniRef50_B5JTN5(87-249:256) Pseudouridylate synthase, 23S RNA-specific n=1 Tax=gamma proteobacterium HTCC5015 RepID=B5JTN5_9GAMM  E=4e-12 s/c=0.46 id=21% cov=63%
---------------KPEGMMSEGDEWGDWQALDRQVWLHFERQREVLVLFALAQEVGGIVLVAHNRRAAADLSALEEAGKITRHYRLEVLGETPPSGSINE-----------------------HSEYRRIDYLTAL---------NASVLAVQSTRGTEDPLRERLAAMGHPVLGDDVYGRQDYR---------DHLHLKGVGLAFTCPFSGESVHF-----------------------------------------
>UniRef50_B6AJ66(2438-2615:2982) Putative uncharacterized protein n=1 Tax=Cryptosporidium muris RN66 RepID=B6AJ66_9CRYT  E=7e-12 s/c=0.41 id=19% cov=60%
-----------------------------------------------------DDEISGPVLISKSDDSYQNLLNQYNEKEIMAEYVFLCHGQLEKHDGYISFeNLATIVCNRIFAKSVTVGSSNCIAKYKVCGIYKHVNSTRDSLL--YSLCRCHSTAGSVNKIRAFMSEIGHPIVCDSKF--LNNKQLNADRRLFPHIFFHCWYLEFLKP-------------------------------------------------
>UniRef50_B2ULL1(2-153:188) Pseudouridine synthase n=4 Tax=Bacteria RepID=B2ULL1_AKKM8   E=9e-12 s/c=0.48 id=20% cov=57%
----------ILAFNKPYGILSQFTKEAPHHRTLA----EFGFPPGVYPVGRLDADSEGLLLLSDEKGLADRLLNPSGRH--PRTYWSQVEGTPSETDLRPLELGGLRIRGhctlpcRARLMRREPDVPPRI------------PPVRYRASIPTSWLELTLVEGKNRQVRRMTAAIGFP--------------------------------------------------------------------------------------
>UniRef50_Q57VS4(184-573:638) Putative uncharacterized protein n=2 Tax=Trypanosoma brucei RepID=Q57VS4_9TRYP  E=1e-11 s/c=0.19 id=30% cov=66%
----------ILVVHKPAGLPTHASGRYFMNSCTAMLeyvlaprRLHAWLVEKdpllqslvstihltgrerdellayyltdsmeedtvpierlPRPCHRLDKVTSGVLLLGISKVAARRVGEALMSKtrqmeeilprrsrfesdegtitfdklhmsgaTVRKRYLARVRGCFPENSMKIRFENCPGDKNKEGVladsnekdttcpinggllivtknshegrrdatdgmnvktfvnsvgvpvlftsplrqyrfsenetiyedlnesygtPIKEMFCQDAMTLCQPLRHYQSDHSHHKDAGTNTeSLVHCVPFSGRMHQIRIHLSDWGHPIVGDVTY-------------------------------------------------------------------------------
>UniRef50_C2KPR0(95-240:278) Pseudouridine synthase n=3 Tax=Mobiluncus RepID=C2KPR0_9ACTO   E=2e-11 s/c=0.49 id=23% cov=53%
------------AFNKPVG--TVSTMQPEDDRPCLGDW-ATKLPQRVFHVGRLDVATAGLILLTNNGDLANRLVH--PRYEVPKTYVAMVQGQVKPGLGKVL-----------RRGVELEDGVTKVDTFKLVEVRR-----------GSSIVQLTLHSGKNRVVRRLLSEVGHPV-------------------------------------------------------------------------------------
>UniRef50_O67444(65-203:249) Uncharacterized RNA pseudouridine synthase aq_1464 n=4 Tax=Bacteria RepID=Y1464_AQUAE  E=2e-11 s/c=0.51 id=24% cov=53%
-----------IILNKPCCYLTQLGRS-PDGRKTIEELIKD-IPERVFPVGRLDYNTEGLLILTNDGELANRILH--PRYKLPKVYLALVEGKVDQKTL-----------KRMKQGIELEDGFAKPDNIRIVRY-----------EGKNTLLEITFHEGRKHLVKRFLGAFGH---------------------------------------------------------------------------------------
>UniRef50_C6JI84(65-202:236) Pseudouridine synthase n=2 Tax=Fusobacterium RepID=C6JI84_FUSVA   E=5e-11 s/c=0.51 id=24% cov=53%
------------ILNKP--LEVLSSSKDDRGRKTVVDLINCK--ERIFPIGRLDYNTSGLIILTNDGELFNRIIH--PKAEIFKEYYVKVLGE-----------IKENNVELLKNGVELDDGITLPANVRILRR-----------EKGKTELLVAIREGRNRQVRRMMDKINHPVI------------------------------------------------------------------------------------
>UniRef50_B3L0G1(123-291:328) Pseudouridine synthetase, putative n=1 Tax=Plasmodium knowlesi strain H RepID=B3L0G1_PLAKH  E=8e-11 s/c=0.41 id=17% cov=62%
------------VLHKPKGFLC--TSNDEKDRASIYSLFPQDimDNYRLVSVGRLDRNTSGVLLLTNEYAWVNKLTH--PKYQRIRTYRVHIEGPAQMKVLKQLATGIYLQDDNRGKENKKIVKKK-RTQPAFIEILREETIKVKDQVKKVSVLNISVREGRNRQIRKMFEQINQPVI------------------------------------------------------------------------------------
>UniRef50_A4S9F7(105-253:287) Predicted protein n=3 Tax=cellular organisms RepID=A4S9F7_OSTLU   E=1e-10 s/c=0.47 id=21% cov=22%
------EDVDglLIVMHKARGVVCSHDVREGTSVYDALPERWRRRKPSIESVGRLDKDTSGLLLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C4FUC8(61-199:243) Pseudouridine synthase n=1 Tax=Catonella morbi ATCC 51271 RepID=C4FUC8_9FIRM  E=1e-10 s/c=0.50 id=28% cov=31%
---------HYYLLNKPEGILS--ATEDRHHQTVIDWLGEGYQHLDLFPVGRLDIDTTGLLLLTNNGQLAHQLLS--PKKKVDKTYTATIRG------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7A9J5(74-206:245) Pseudouridine synthase n=1 Tax=Thermus aquaticus Y51MC23 RepID=B7A9J5_THEAQ  E=1e-10 s/c=0.52 id=22% cov=50%
-----------LLLHKPAGYVTSRKEG-----PSVYALLEGFPTRDLSPVGRLDKDTEGLLLFTTDGELLHRLTH--PRHKVEKRYLVHLLHPATAADVRAFQEG-------------------------ILLSGEKTLPARLHLGEDPTWVELTLLEGRFHQVKRMFQARG----------------------------------------------------------------------------------------
>UniRef50_Q13UY7(84-222:261) Pseudouridine synthase n=45 Tax=root RepID=Q13UY7_BURXL   E=4e-10 s/c=0.49 id=30% cov=22%
-----YREHAYLLLNKPAGYEC---SRDPQHHLSVFSLLPPQFaGRGVQCVGRLDQDTTGLLLL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0LG30(66-204:250) Pseudouridine synthase n=1 Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LG30_SYNFM  E=7e-10 s/c=0.48 id=20% cov=49%
------------------------TARDPQGRKTVFDFVPD-AGARLFPVGRLDFDAEGLLLLTNDGLLANRL--QHPRYGVTKTYEVAAMGHPTPAAL-----------DRLRTGVMLEEGMTAPAEVTVI-----------GSSPRSTRLRIVLHQGWNRQIKRMGEAVGHPVL------------------------------------------------------------------------------------
>UniRef50_D1N1S2(68-201:241) Pseudouridine synthase n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N1S2_9BACT  E=2e-09 s/c=0.48 id=21% cov=52%
-----------IMLNKPRGYVC--TNADPHADLKAVDLIRLTPPLRLFSAGRLDKDSEGLILFSNDGDYVARLTH--PRHEILKVYQVRVRREFKPAELEQMRRG-------------------------VLERGELLKVHAVSRCGDCTYL-ITLNEGKNREIRRLTAALGSP--------------------------------------------------------------------------------------
>UniRef50_UPI000155C728(59-257:258) PREDICTED: similar to RNA pseudouridylate synthase domain containing 3 n=1 Tax=Ornithorhynchus anatinus RepID=UPI000155C728  E=3e-09 s/c=0.33 id=20% cov=75%
---VVQREGHLVTLNKPQGLAVIGKPGDVTVHSVLPELsQRLGFDQPLEVVKSAEKESSGLVLLSGCPKTSENLRNYFIWSHRAKrpavTYRAITVGIPNPFEGEVKTALKLEQKWGEKWFVGTALGQ------RFLLSPDTMPQKQVLDER---LLH------RLHLTQQQMSLV--PI-------HLHLHQLLLPKKGLK-------------PGHN---VLTAPPPPFFVQTLERLQLR-----------------------
>UniRef50_UPI00016C3D27(63-200:271) ribosomal large subunit pseudouridine synthase B n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C3D27  E=4e-09 s/c=0.47 id=24% cov=52%
------------AVNKPVGHLC--TNHDPAGRPRAVDLL-PHVEQRVYTVGRLDEGSDGLLLMTNDGDLAQGLTH--PRYGVPKMYFVLVAGRPT-----------DDDLQKLMDGVWLSDGK-----------VRAKSAKRIKAQGNGTWVRVVLTEGKNREIRRMLAKFGH---------------------------------------------------------------------------------------
>UniRef50_A3JIZ1(121-263:367) Pseudouridine synthase n=1 Tax=Marinobacter sp. ELB17 RepID=A3JIZ1_9ALTE  E=5e-09 s/c=0.45 id=21% cov=24%
----------VLIYNKPEGEVT--TRKDPEGRPTVFDRLPRLREHRWISIGRLDLNTTGLVMFTTDGELANRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5WE78(54-201:243) Pseudouridine synthase n=10 Tax=Firmicutes RepID=Q5WE78_BACSK   E=5e-09 s/c=0.43 id=26% cov=35%
--PVRYKAELYLMLNKPAGVVT--ATEDARQKTVLDLMKNEWGHMKPFPVGRLDKDTTGLLLLTTDGAFSHELMA--PKKHIAKEYRALVEGKVTQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q30U38(45-213:312) Pseudouridine synthase n=12 Tax=Epsilonproteobacteria RepID=Q30U38_SULDN  E=5e-09 s/c=0.38 id=19% cov=62%
-VDVVYvsgkpvtpRDKYtVIVYNKPKGELV--TKSDPKERKTIYDTLPKEYKHYV-PVGRLDYASEGLLLLTDASKVASALMES----NLERIYKIKIKGEVTSEMEAAMLNG--------MMLDDATAGGHSHSKVTSMEFKPFIGYKIQKNEPNYSILKVALSEGKNRELRRFFAHFGTDIV------------------------------------------------------------------------------------
>UniRef50_Q5SLZ5(65-197:243) Pseudouridine synthase n=4 Tax=Bacteria RepID=Q5SLZ5_THET8   E=8e-09 s/c=0.48 id=22% cov=50%
-----------VLLHKPPGFVTSRTEG-----PSVYALLQGFPTRDLSPVGRLDKDAEGLLLFTTDGLLLHRLTH--PRHKVAKRYLV-----------HLERPVGPKDQEAFREGILLDGKKTLPAELTPLE--------------DPTWAEVVLKEGRFHQIKRMFRARG----------------------------------------------------------------------------------------
>UniRef50_Q31GA0(82-220:317) Pseudouridine synthase n=2 Tax=Gammaproteobacteria RepID=Q31GA0_THICR  E=2e-08 s/c=0.44 id=26% cov=24%
----------VILYNKPEGQVC--SRKDEKGRETIFTSLPRIINSRWISVGRLDINTSGLLILTNNGELANRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2R7V9(95-232:811) Pseudouridine synthase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R7V9_9PLAN  E=3e-08 s/c=0.45 id=27% cov=29%
------------VVNKPEGVVT--TNYDQAGRTRVIDLV--PTDERVFAVGRLDRASEGLIIVTNDGEFANRVTH--PRYGVTKTYLVRVAG------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6XLQ6(73-210:247) Pseudouridine synthase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XLQ6_HIRBI  E=4e-08 s/c=0.44 id=24% cov=52%
-----------VMLNKPAGVTC---SRKDSGTLitELFPSRWDKRDPLLSPIGRLDKETSGLLLLTDDGQLNHRVSS--PKTQTPKRYHVILDRDLNGDEDSIFAAGEL-----------------------MLESETKPLLPAELSALGKREAILTLHEGRYHQVRRMFAAVG----------------------------------------------------------------------------------------
>UniRef50_A5WGV6(107-236:345) Pseudouridine synthase n=7 Tax=Moraxellaceae RepID=A5WGV6_PSYWF   E=5e-08 s/c=0.47 id=24% cov=24%
----------VLAYYKPEGEIC--SANDPEGRTTVFERLPKLTHDRWIMVGRLDINSTGLLLFTNDGELAHRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0SBU8(50-199:243) Pseudouridine synthase n=2 Tax=Leptospira biflexa serovar Patoc RepID=B0SBU8_LEPBA  E=2e-07 s/c=0.39 id=22% cov=55%
---VVYYDEtlnrkefYYFMMNKAPDCIT--ATEDPREKTVMDYLSERHRNMNLFPIGRLDKETEGLLLFTTDGTLAHYYTS--PKHFVEKEYYAEISAPVTAFDISQFESGITLDDG-----------------YKTL-----PARLAIPDPSNPHIATVWLREGKYRQIRRMFQSLG----------------------------------------------------------------------------------------
>UniRef50_A6WK95(76-253:256) Pseudouridine synthase n=12 Tax=Gammaproteobacteria RepID=A6WK95_SHEB8  E=2e-07 s/c=0.33 id=25% cov=55%
-------DEHILqanapvyvMLHKPIGVVS-ATKDIQHKT--VIDLLDCEARDELHIAGRLDLNSSGLLLLTNDSRWSDALMS--PTHKVDKVYRVTLANPITEEYIAAFA-------EGMYFGFEDITTQPAKL---VILADNVA--------------EVTLHEGKYHQIKRMFGRFRNPVVG-----------------------------------------------------------------------------------
>UniRef50_Q9HZ55(78-178:386) Ribosomal large subunit pseudouridine synthase B n=67 Tax=Gammaproteobacteria RepID=RLUB_PSEAE  E=2e-07 s/c=0.58 id=23% cov=33%
----------VLIYNKPEGEVC--TRDDPEGRPTIFDRLPRLRTGRWINVGRLDINTTGLLLFTTDGELANRLMH--PSYEMDREYAVRVRGEVTEEMI-----------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6W7S5(64-197:231) Pseudouridine synthase n=2 Tax=Anaerococcus RepID=B6W7S5_9FIRM   E=2e-06 s/c=0.41 id=29% cov=27%
-------------LNKPIGFIS--SNYDPHNKKDLNSLVK--IDHRFFCAGRLDKDSHGLMLITNDGKITNKLIH--PSKKIEKTYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7G1Y5(33-217:286) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G1Y5_PHATR  E=4e-06 s/c=0.29 id=26% cov=45%
-----------------------------------------QIRSKLHAIGRLDAETTGLLLLTNDGGLVHHVTnkdsvsHQHHGNPVFKTYEALVMGFYDNHSPLLEKMRTQGVNIGDK--------------YGGTTRPVDELIVKTNPTLKSTLVSLTICEGKNRQIRRMFHALG----------------------------------------------------------------------------------------
>UniRef50_Q1LJQ9(64-200:238) Pseudouridine synthase n=3 Tax=Burkholderiales RepID=Q1LJQ9_RALME   E=4e-05 s/c=0.37 id=22% cov=52%
-----------VMLNKPTGYECSQRPRHHPSVYNLLPV--PLRQREVQAVGRLDHDTTGLLLLTDDGQFIHA--QTSPKKQVPKIYEVTTFDPVTPEQVEALR-----------------------TGVKLDDEPAPIAADACEATGERSL-RLTLLQGKYHQVKRMVAAVG----------------------------------------------------------------------------------------
>UniRef50_C0ACE6(84-218:253) Pseudouridine synthase n=1 Tax=Opitutaceae bacterium TAV2 RepID=C0ACE6_9BACT  E=7e-05 s/c=0.37 id=23% cov=52%
----------LLMLHKPTGFVCSHDEREGPRVYDLLPPRWRARNPQVTSIGRLDKDTSGLLILTDRTELVHTYTS--PRHKVPKLYRATLDRDVPASLVDLFAAGTLQLDG---------------------EKAPCAPATLRLPAPRVA--ELVLVEGKYHQVRRMFAA------------------------------------------------------------------------------------------
>UniRef50_Q00UF3(334-428:428) Chromosome 16 contig 1, DNA sequence n=1 Tax=Ostreococcus tauri RepID=Q00UF3_OSTTA  E=7e-05 s/c=0.53 id=24% cov=35%
---------------------------------------------RVWAVNRLDAPVSGVWLCATSvKASLKAREWLSKPGTSTKTYLARVSKgsaltTPDGGLRIDAPLWKNAKTSVAELRPESEGGKPCATRIFLLEQ------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6FY13(54-211:238) Ribosomal large subunit pseudouridine synthase B n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6FY13_9DELT  E=0.0001 s/c=0.31 id=23% cov=22%
---VLREHAHLM-LHKPHGVVTARADG-RHPTAYALLEGAPLFA-ELRAVGRLDLDAVGLLL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q9I5J6(62-198:230) Ribosomal small subunit pseudouridine synthase A n=25 Tax=Gammaproteobacteria RepID=RSUA_PSEAE  E=0.0002 s/c=0.36 id=23% cov=47%
-------------LHKPMG--CVSATRDPQH-PTVLDLFPEDLRDDLHIGGRLDYNTTGLMLLTNDGQWSRRLT--LPGSRRDKVYYVETEAPIDQRYVDAFA---------------------AGLHFRFEDLVTLP-AQLEPIGPRCA--RLTLHEGRYHQ-------------------------------------------------------------------------------------------------
>UniRef50_Q0C148(70-212:372) Ribosomal large subunit pseudouridine synthase F n=9 Tax=Alphaproteobacteria RepID=Q0C148_HYPNA  E=0.0004 s/c=0.34 id=23% cov=32%
-------DNQLsVILNKPVGYVSgTPEPGEipairliSEENLSGSAHAIPQRSNKMAPLGRLDKDSHGLLILSEDGVLAKAIIGPLSD--MDKEYLVKVRG------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7FTM7(68-214:252) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7FTM7_PHATR  E=0.0004 s/c=0.32 id=22% cov=32%
-----------ILVHKPVGYVsSQPeTDSIPQEQASSRRLFHPRTQLGWATAGRLDINSTGLLVLTQSGRVAKTLIG--PDVRVDKEYLVRVRPSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------
