>ss_pred
CCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEECCCCCEEECCCCCCCCCCCCC
>ss_conf
964663027640102899999855313786423467606752121025893799998320117610686799999999740210121678989999976089999999999999999999972983881035542787766608999999996357341455589997899987542357788887434787124578620404899999850597189652764578899988876192699964103789899998533284343247872599997167689999998717898867999999815928998189858871587546583679
>batch____
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC
>UniRef50_B8D1S4(1-334:334) Hydrogenase expression/formation protein HypE n=3 Tax=Bacteria RepID=B8D1S4_HALOH  E=6e-79 s/c=0.89 id=44% cov=99%
MNTISLAHGNGGKMMEDLIDNLFLKYLNNDIINKKDDASPVPEIKGVP-----VISTDTFVVDPIFFPGGNIGKLSICGTVNDLAVTGAIPLYLTVGFILEEGLPIKHLEKIIISMAEVSREANVKIVAGDTKVVERGKGDKIFINTTGVGMIGDKLKLSDENIKLGDKVIINGSIAEHGLAILMERNQMDFSTSIKSDCCTLSDLIVTlLSETNGIKFMRDPTRGGMATVLNEIATRYNVGIEIEEEKVPLGDEIKSLCKILGLDPLYLANEGKVLIIADREKSEKIVDIMRRHPYGRNSSIIGTIVDNndQQVYLKTRIGGKRIITKLMHDMLPRIC
>UniRef50_D2ATM4(116-446:446) Hydrogenase maturation factor-like protein n=35 Tax=Bacteria RepID=D2ATM4_STRRD  E=1e-75 s/c=0.86 id=51% cov=97%
-DRITLAHGAGGKATHTLIEAVFLEAFRNPLLEPLEDGAVV---------DGLAFTTDSYVVTPLFFPGGDIGDLAVNGTVNDLAMCGARPRYLSAAFIVEEGFPVADLRRITASMAAAARAADVWIVTGDTKVVENGKADGCYITTSGVGTVERPIRLSAAAARPGDVVIVSGPIGEHGVTVMLARGELDIQADLTSDTAPLNTLTGRLLDACGdgqVRCLRDATRGGVATVVNEIAVASKVAVVLEEDAIPVCPAVRGACELLGIDPLYVACEGRMVAVVAQRSAEAALAALRSHPLGSEAAVIGRIGDDPPglVLLKTSFGGTRIVDLLVGDPLPRIC
>UniRef50_B2TM78(1-337:337) Hydrogenase expression/formation protein HypE n=4 Tax=Clostridium RepID=B2TM78_CLOBB  E=1e-74 s/c=0.84 id=44% cov=99%
MNNkiITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLNEIK-----GKIATTIDGFVVDPIFFKGGDIGKLSLCGTINDLAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAKTAKESNVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNiLNVNNIKSGDKIILSGTIGEHGMCIVNKRENLNIDSEIKSDCAPLNSLCEIILNTSnNVRIMRDPTRGGIANTLNELSRSSLKSMMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPLGKDAAIIGEVIEenKGAVYIKGLLGSTKVLQMSQGELLPRIC
>UniRef50_C9KK60(12-348:348) Hydrogenase expression/formation protein HypE n=1 Tax=Mitsuokella multacida DSM 20544 RepID=C9KK60_9FIRM  E=5e-65 s/c=0.74 id=46% cov=99%
--RVTLAHGAGGRQTAALIARVFARHFQNPDFT-ADDAAILPVGNFAT--GRTAFTTDGFIVSPWQFPGGNIGKLSICGTVNDLACMGAVPRYLSCAFQIEEGFPLRDLDAIAAAMAETAKAAGVRIVAGDTKVAGRGQVDGVFITTTGLGELLPDAEPSGSRAEAGDAIIVTGDVGRHGAAILVARRDFAIDAAITSDCAPLAATVRALfaavPDKSAIHTIRDATRGGVGTVLHEIAAESHVGIELDAPAIPVAPEVRGVCGLLGLEPLYLACEGRLVLFAPQAIAPKLVETLRALPDSRQAAIIGHVTPDFSGRvvLRTEIGTKTLLPEPSGELLPRIC
>UniRef50_A3DKG6(7-346:346) Hydrogenase expression/formation protein HypE n=1 Tax=Staphylothermus marinus F1 RepID=A3DKG6_STAMF  E=4e-37 s/c=0.46 id=34% cov=96%
---ITTVHGSGGFETLEIIEKLIVHRVPE-NLRKVLDGVGLDVlddgSSMRIGNTHIVISTDNFTVKPLFFPGGDIGHLAVSGVLNDLVMMGARPIAFMDGIIVEEGFPRDDLDRILESMIKLLKENNVALIGGDFKVMPKKSLDGLIISGTGIGLAEKPI---IDKIKPGDKIIVTGPIAEHGATILaaqlgMLEQAQGLRSDTRPLVKTVLPILEKYRD--HIHAARDPTRGGLSIVLNEWVRGTKYTIVINRSTIPIRDEVRQFLDALGIDPLGVAGEGLAILSVDNEVADEIVEELHRRgePY---ATIIGEVIVPEEEYLAGRviaiteVGGKVVVQ-PNALNLPRIC
>UniRef50_B0TCN4(6-360:360) Hydrogenase expression/formation protein hype n=6 Tax=Firmicutes RepID=B0TCN4_HELMI  E=1e-117 s/c=1.19 id=48% cov=98%
---ILLAHGDGGALTHRLVQEIFLRHFDHPALRDLTDAALLHLPE-----GRLAMTTDTFVVKPLFFPGGDIGKLAVAGTVNDLAVSGARPLYLTAAFILEEGFPLADLEQVVASLARTAREAGVAVVAGDTKVVERGCGDGVYINTTGAGVVPAGRDLGYHRIMPGDAVIVNGTIGDHGLAILSKRAGIEFDTPVESDCAPMNGLTDMLLErfAEAVRFMRDPTRGGVATTLNEVAQSTGLNIILEEQALPVREEVQGAAELLGLDPLYLANEGKVLIVAAPEAVEEILTTLRRHPLGLNAAAIGRVEAGTGvgrgpgqgagqrtgqgsgqgagrgrVFLRTPLGGHRIVDMLAGDPLPRIC
>UniRef50_C5ZXL6(6-340:340) Hydrogenase expression/formation protein HypE n=4 Tax=Helicobacter RepID=C5ZXL6_9HELI  E=1e-116 s/c=1.26 id=44% cov=99%
---ITLSHGSGGVESQKLISELFYPFLEGCVIGNGEDAGIGELDSISQ--GKFAISTDGYTISPLFFPGGDIGKLSICGSCNDVAMMGAKPKYLSASFMIEEGFLIDDLKKILDSFGKTLKASGAKLLSGDTKVLPKGTLDKIFITTTAFGEfLYPHLQISAFNIPQDCCILVSGEIGNHGAVVYSKREEISLQSNLESDCQLLYPSLEELfKNNLSIYALRDATRGGIASVLNEWANASHIGIEIEEETLPIKDEVRGICELLGFEAWNLANEGMCVLAIAKEDSKKALEILKRTPAGKNATIIGYTTSTnlNKVVLKTAYGAKRFLDYPSGELLPRIC
>UniRef50_A6LXR5(1-333:333) Hydrogenase expression/formation protein HypE n=3 Tax=Clostridium RepID=A6LXR5_CLOB8  E=1e-115 s/c=1.26 id=45% cov=98%
MNKmIKLIHGDGGKHTKILIEQLFYKYFNNNILLQEQDSA-----TFTAVQGKMAFTTDSFVVKPLFFSGGNIGKLAVCGTINDLAVSGAKPFYLSSSFIIEEGFSMQSLEEIVKSMGQTCLECGAKIVTGDTKVVEKGSVDGIFINTSGIGYIINGYEVKP--IEEGDKIIVTGEIGEHGTTIAVERYNLKVKGDYKSDCAPLFHFIEELKEqFPSIKIMRDPTRGGLSTVLHEFSSLCKLGIHLIEKEIPISESVKAINNLLGLDPLYMACEGRMVLVVKETEAKKVLDIIRSIDQGKGARIIGEFIKDsnQNIFIENGFGGKRVVSPLEVSMLPRIC
>UniRef50_B2KBC5(3-335:335) Hydrogenase expression/formation protein HypE n=1 Tax=Elusimicrobium minutum Pei191 RepID=B2KBC5_ELUMP  E=1e-105 s/c=1.15 id=42% cov=98%
-NKITLAHGAGAEVSRGFIKKTLLKYFKSKSLAELSDSAKIKI-----NSKDILFTTDSYVVNPVFFPGGNIGDLAVCGTVNDISVSGGDIKYISLGLIIEEGLDLKELEQILKAVALRAKEAGVEIVTGDTKVVERGGADKIFINTSGIGQAIADATVKARNIKKGDKIIVSGNLAEHGISVMNERHKLGLKG-LKSDVAPLNKITKAlfLKFDKDIHMTRDLTRGGLAGALKEIAEQAKKDIELEESRVPLSKAVKGAVSILGVDPLQTANEGKFVCIADAKKAESVLKLLKTFAYGKDAKICGTVlkTRKGRVYIKTPLGASRALAEHEGSNLPRIC
>UniRef50_B1YBW5(25-366:366) Hydrogenase expression/formation protein HypE n=7 Tax=Archaea RepID=B1YBW5_THENV  E=2e-93 s/c=1.01 id=38% cov=97%
---IKLSHGSGGVETSEIVEKLFLRRLP-EGLKKVAGGLGLDFpddaaAIPMADGRYLVVTVDAYTVNPPFFPGGDIGMLAASGSINDVLMLGGRPLAMLDSIIAEEGLPYETLDRVVKSFLSVLEAEGVALIGGDFKVMPKGQLDKIVITTVGIGVADRII---VDKPRHGDKIVVSDFVGDHGAVILMLQmgdvdkpEQLQLKSDVKPLTKLMVPLVEKYGEY--IHAARDPTRGGLAMVLNDWAKAGGGVIVVEEESLPVRPEVASYAGMLGIDPLYLASEGAAVLAVDPAVAEEVVKFMRGLGF-QNARVVGEFREarqhRGYVLLKTVAGGLRILEPPRGDIVPRIC
>UniRef50_B8D3R7(10-349:349) Hydrogenase expression/formation protein HypE n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D3R7_DESK1  E=1e-85 s/c=0.94 id=34% cov=96%
---ITTLHGAGGIESWNIIEKLIrgrvpRDLWSTPGGAGLD---VLDDGSYIRIGEsYIVFASDAYTVKPLFFPGGNIGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELEDIVDSMVKTLVENNVALIGGDFKVMPRGSVDGVVISGFAIGV--SGKPPVVDSIKPGDKIIVTNYIAEHGSTILaaqldMLNDAPGLKSDVKPLVKTVLPVIEEYRDY--INAARDPTRGGLAAILNEWSRSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEALRRN--GENPYIIGEVVEprsrelRGRVVALTEVGGLTII-PPQAYNLPRIC
>UniRef50_Q5ZXK3(13-320:325) Thiamine monophosphate kinase (AIR synthase) n=6 Tax=Legionella RepID=Q5ZXK3_LEGPH  E=7e-59 s/c=0.75 id=27% cov=89%
-----------------LIDHYFKSipcKRNDVLFGIGDDAACLQ----VPDGMHLLVSTDTLVSGIHFLPQWdpyDIACKAVMVNISDMAAMGAQPCWVTLALTLPE-LNQSWLDSFARGIKDSLGLYNVDLIGGDTT---KGP---LSITLTIMGLTPQGQAIRRCGAQAGDAIMVSGELGAAGLAVKLLDEHKKVNAkdkvELMNKLLHPKPRVDLCHLLRKYATSAIDISDGLGADLNHICAASGVGANLFEEAIPRHPLLNQYCPEQALDlALSGGDDYELCFTVSIQQLDSFNRDLQKENLI--CFPIGVIEEKPGLRIQSA-------DSPSKELQPR--
>UniRef50_C7NS45(10-328:345) AIR synthase related protein domain protein n=1 Tax=Halorhabdus utahensis DSM 12940 RepID=C7NS45_HALUD  E=9e-57 s/c=0.70 id=33% cov=85%
-------------------DREFFDEYIYPRLGADRDdvrlqpQHGVDFGVADVGGQALAMATD-----PVFIvPAAGFERAAWFAFHilfSDVAVSGLDPAYLSVDFNLPPEITDEQFETVWETFDQEAAELGASIVTGHTgryagcnypmvggaTTVATGDFDDLVTPD---GARPGDRVI----VTKGPAIEATGLLSVHFDSLM--------DGEVPADeiqaakdrFYDMSPIQEAMVASAAgpVTAMHDATEGGVYGGLFEMARSADVGFEIERDRIPVQPGVEAACDFFDIDPWISISEGTLLATVDPDGASDVLSALKSE--GIPAADAGRVVEGSGLTVDG-----QAVDHPGKDP-----
>UniRef50_UPI0001B4B0DD(35-338:339) hydrogenase expression/formation protein HypE n=1 Tax=Streptomyces sp. C RepID=UPI0001B4B0DD  E=7e-55 s/c=0.71 id=37% cov=82%
-----------------------------------------------------------HVVDPPFYGSGDIGRIAVCATVNELAAAGARPLALTLSAVVEAGLPLERLHRLARSVRDAAREADVVVAGVDVRVVRAGEADQVYLHTTGIGAF-HGAPLDTRDARPGDRVLLSAPLGGHGAHILSVRRGLGFESLVPSGCAPLAGLLERARAAAsgdGIRAVRTVTRGGLAAALHAYARELGHTLRVEESALPVQYEARMALEAMAVDPLHASSESCLCLLVAPDAAPGVLAALRTHPYGRFAAEIGTVVEDGAApveLLRDRGGAVPVTPEPAA--FPRL-
>UniRef50_B0R9W2(8-314:340) Hydrogenase expression/formation protein n=3 Tax=Halobacteriaceae RepID=B0R9W2_HALS3  E=1e-53 s/c=0.69 id=33% cov=84%
------------------IDAEFFAQHLSPNLGADDDavtvgpQYGVDFGVLSIGGQRLVVSADPVSVNP----GVGIeraGRLALHSVLSDVAVSGVPPSFLSITLVLPASARDDTIAALWDAMATECERLGVSVVTGHTA---RQDVSFPWIGGaTAMGVGDPAEIVRPDGATAGDTVLMTHSpgaevaglfaalFGDHLDVADDTVERADArleDTTVVGDaCAAASAP---------VTAMHDATECGIQGALVELATAAGVSISVSSDAVPVPEDVSAVCADLGLDPWQVSSRGTLLVTVPEAHADTAMAALDAR--NTPVAAIGTVSEGSGVTVDGT-------------------
>UniRef50_C7NRE1(7-328:340) AIR synthase related protein domain protein n=4 Tax=Halobacteriaceae RepID=C7NRE1_HALUD  E=1e-48 s/c=0.61 id=28% cov=90%
------------------IDTETFDSVIAPHLGADREdvtigpQHGVDFGVLSVEESAVVVATDPISILPeLGFE--RAGRVALDIVLTDVAVSGIAPTHITVSLSLPPEMTDEELGQTWRGMADHAENLGVSIVSGHTARYE--GIEYSWVGGaTALGVGDPADIVRPDGANPGDAvVLATGPGAETAGLFATLfPEALELPAKTVATAQ------ECVGDILGVadattaaaagelTAIHDTTEGGVIGGLTEMATGAGVTFDVRRDPAPVQPGVAAVCDAIGVDPWTVTSAGSLLITAPPATAESVVEALEAH--GTPAAVIGSVEECSDTSADVILDGER-VEPPESDP-----
>UniRef50_D2RZQ8(7-326:346) AIR synthase related protein domain protein n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2RZQ8_9EURY  E=7e-43 s/c=0.55 id=27% cov=90%
------------------IDRQFFDRHVAPNLGADRDdvavgpQHGVDFGVLEIGGQALVTATDPVSIMPqLGLE--RAARFALDLVLADVAVSGIPPSHLSICFTLPETMTDDEFATVWKTIHEECVDLGVAVVTGHTARYS--DPSHPWVGaATAMAVGDPDEIVRPDGARPGDRLLLTTGPAVESVGLLSTlfadQLEAALPGDVIDDAQDRLEEVYCVRDALAaaaagpVTAMHDVTEGGLAGALNEMADGAGARFSVDRDAVPMRPGVQEVCDHLEIDPWAATSSGSLLLAVAPEGVDDVVAALEDRD--TVVAEIGRVEEPSG----TDGDGEVVVD---GDRLP---
>UniRef50_A8MLK1(4-324:330) AIR synthase related protein domain protein n=3 Tax=Clostridiaceae RepID=A8MLK1_ALKOO  E=3e-39 s/c=0.51 id=25% cov=91%
-----------GKVPTEVLKEVIFSNLKNRRPEVLvrpnigEDCAVVDFGDYVC-----VMSTD-----PITGAAKDIGSLAVHISCNDIASSGVEPLGIMLTIMAPPHTTKEDLSLVMSEANKAAASVNVEIIGGHTEITD--AVNRMIISATAIGRQLKEKLVLSEGAKIDDAVFMTKYTGLEGTAIIARDLEEKLKEKI-SD-ATIQTAQEFLKDISvvkegitagevGVHSMHDVTEGGIFGALWELGEASGIGIEIYEDQIPMRPETLEICHYLSIDPMRLISSGVMVMTIAQDKKEALMEAFKRENLIL--TEIGRMVEKDRIIISAAKGI-RALDPPDVDEL----
>UniRef50_B7R791(21-338:348) AIR synthase related protein, C-terminal domain n=2 Tax=Thermoanaerobacteraceae RepID=B7R791_9THEO  E=1e-38 s/c=0.51 id=24% cov=92%
-----------GKIPVEVMKRSIFPYLGTKRKEVLVHSQLGEDSSIIDFGEYVAVlSTDPITAADKL-----SGFLSVIISCNDLAACGAEPIGILTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGGHTEV--TQAVNKPVISTTAIGIARKGKYITSKGAKIGDDVIVTKALGLEGTAILATDYEdlliKHFGKDFVLKAQSFINEISVIEEGLiasqnGANAMHDITEGGVLGATYEISEASGLGIEIYEEKLPFRRETKEICKFFGLNPLKLISSGSMLITA--EDGNRIVKAL--SEKGIQATIIGKIV-KEGRYLITSSGKEEILPPEKDEI-----
>UniRef50_B0KA39(4-321:331) AIR synthase related protein domain protein n=10 Tax=Clostridia RepID=B0KA39_THEP3  E=5e-38 s/c=0.51 id=23% cov=92%
-----------GKVPVEILKRSVFPYLGVKRKEVLVHSQLGEDSSIIDFGEYVAVlSTDPITAAEKL-----SGFLSVIISCNDLASCGAKPIGILSTILLPEGSDESVLHNLMEEIDKAAKKLNIEVLGGHTEI--TTTVNKPIISTTAIGMAKKGEYITTKGAKIGDDVIVTKALGLEGTAILAtdyedlllKRYDKDFILKAQSFINEISVIEEGLIAAQnGANAMHDITEGGILGAAYEIAEASGLGIEIYEEKLPVRPETKEICRFFGINPLKLISSGSMIITAS--DGDKIVKSL--SEKGIQATIIGKII-KEGKYLITSKGKEEITPPERDEI-----
>UniRef50_D1C5Z5(14-345:359) AIR synthase related protein domain protein n=7 Tax=Chloroflexi RepID=D1C5Z5_SPHTD  E=1e-36 s/c=0.47 id=26% cov=93%
-----------GKISPEVFEQVIKPRLGRHRPEVLvGPQHGVDVGIIDIGGGRvMAVTTDPFFIVPQY--GWeRAAWFAVHILASDAATSGLPPTYFVVDLNLPRNITSEGLEALWHAVDATCKEIGMAIVTGHTARYD--GTDYPMVGGAMVMAVgERDRYVTPTMARVGDAVIVtkgaaieaTGLFGvtfpdriaaAYGQEIARQAEETFYQMSVVKDAMT---AVEVGVRDAGVTAMHDATEGGVWGGLYEIAVASGVGMVVEQNAIVVSPAAQAVCDLFGMNPYAAISEGTLIITCRPEKAGAVLTRL--EDAGIAATQVGEITPPEEGIRLVRDGREEPLEHPRVDP-----
>UniRef50_C9L525(76-342:344) Hydrogenase maturation factor n=1 Tax=Blautia hansenii DSM 20583 RepID=C9L525_RUMHA  E=5e-36 s/c=0.58 id=26% cov=77%
----------------------------------------------------------------------DIGGHSVHITANDLAASGAEPVGIMLTMLLTPDTEEAQLKEIMQDVEKTCKELNMEVLGGHTEVTD--VVKQTLISLTGVGKMKKENVLTTASVKPGDDIVVTKWIGLEGTSIAAkEKESLLLEHFAPPFVETAKKFDQYLSVIPeakiaaewGVSAMHDITEGGVFGALWEMGSGSGVGLDIDLKEIPIRQETVEVCEVLGLNPYILMSSGSMMIAAKDGYG--LVRKLKQA--GIEAAVVGKATDGNDRILRNG-EDTRYLDKPQSDELYKI-
>UniRef50_C3N301(65-393:402) AIR synthase related protein domain protein n=9 Tax=Sulfolobus RepID=C3N301_SULIA  E=2e-35 s/c=0.46 id=25% cov=94%
-----------GKINEDLFNKVIYPHLGEKRTEVLvGPQHGVDTAAIDLQDGRiLVVKTDPVFIVPQFgFKKA--AWFAVHILASDVMTSGIPPQYAVIDVNLPPKIKDDEFEEMWIGIHEALKEIEVMVVGGHTGVYE--GTDYPMVGGfTMFGIGEKEKLGMPSKVRVGDSVIMTkGPaIEATGLLTNLYPEYFKqrLDKETFNEAYNIYWKMSCWKDGliasrIGIHLMHDATEGGVFGALTEVARASGKGMNVYEDKLFINSAVREVTRLVNIDPWISISEGTMIIVTDKG--KDVREALIKE--GIEAEIIGEIVDQSGdVKLVKKDGSRVKIEHPLEDPFWR--
>UniRef50_B0R2T1(10-324:339) Hydrogenase expression/formation protein n=2 Tax=Halobacterium salinarum RepID=B0R2T1_HALS3  E=2e-35 s/c=0.48 id=29% cov=88%
----------------------FFDDHIAGRTGADRDDVRLgptygaDFGVVAIADSVVAMATDPVFV----LRALGIERAAWFAFhicVSDVALSGLSPAHLAVDLNLPPDTATETFDAIWEVFDREARALGVSLTTGHT-----GTYEGCSFPTVGgataLAVGAAEDVVTPTGAQPGDRVVVtkgpavetTGMLGVLFGDRLPISAAAAAAARDRFADATPVRDAATMAAAGEVTAMHDATERGLANGLHELAAASGVGLSVARDAVPVLPGVRAVCEQFGMDAWAASSEGTVIAAVDPGSVDAVLGALGDE--GIPAADVGVVEAGSGVTVDGD-----PLAEPAADPL----
>UniRef50_Q6KZH8(1-303:334) AIR Synthase n=1 Tax=Picrophilus torridus RepID=Q6KZH8_PICTO   E=8e-35 s/c=0.50 id=26% cov=84%
--------------MTGKISREFFESNIIKRLGFLRDEVvvppenGVDVGIVRLGNGYLAVTTDPFYIDPVF----GLKKAAWFGFhilLSDIYTSGIPAMYMSIDLNLPQSMSDDEFNEIWTVINDESKKYNVMVVTGHTARYA--GVSYPMIGGvTLMGY--GDRYITTKNAGDGDIIIMTKTCALEASCILSytfpeyIEKHLGMDTlkKLNDLFYKMTCVNEEILSidfgLDKITSMHDATEGGIINALYEIGKASGHGVIVNKNNINIDESVSRVTKLFNIDPLRSISEGTLLITVKRNFADELLLKLRSA--GIDSYIIGE-------------------------------
>UniRef50_A4YFC4(5-323:332) AIR synthase related protein domain protein n=3 Tax=Sulfolobaceae RepID=A4YFC4_METS5  E=3e-34 s/c=0.46 id=24% cov=89%
------------------IDRKVFDEVIYPHLGKRLDEVivppltGVDTGAIDLGDRVLVVKTDPVFIVPQF------GMKkaswfAVHILASDVMTSGIPPRYALLDLNLPPSMTDEEFREMWVGIHEALLEIGVMVVGGHTGRYE--GVNYPMVGGfTMIGIGEKEKLGHPSKVKPGDYVIVTkGPaIEATGLLTNLYPEFFreRMRSDLFKEALDMYWKMSCWKDGLiasqvGIHMMHDATEGGLWNALVEISEVTGKRINLVGERLFINPAVREVTRIVGIDPFSSISEGTMVIVTDKEKVKE--ELLRN---GIEAEIVGRVESGEGVYVDG-----KRIEKPSEDPFWR--
>UniRef50_B5Y6B6(50-310:339) Hydrogenase expression/formation protein HypE n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y6B6_COPPD  E=3e-32 s/c=0.54 id=24% cov=74%
-------------------------------------------------------------VDPIVGAVNGIGWLAVHVACNDIAASGIKPRWVQLLVMLPSLDQPEELKQIMSDAARAADSLNVTIIGGHTE--ASNGLRRPLVAATALAPACGKRVVRTSGAKPGDIIYVTRGVGLEGTGILASDFAVEARKRGLTD-QDLNEALKLLssvsvvsealkLADLGATAMHDVTRGGILETLLEIASCSGVCMEVDRSRIPVPEVVKRFANAFEFDPLKMISSGTLVATLPPEMCETAEALFENQPC--KLFRIGVVTEGRGVLLR---------------------
>UniRef50_C7H113(13-318:347) Hydrogenase maturation factor n=1 Tax=Eubacterium saphenum ATCC 49989 RepID=C7H113_9FIRM  E=1e-31 s/c=0.45 id=23% cov=88%
-----------GKLDSDILEKIVFGNIRYKSADViKRAGLGEDCAVMDFGEYDCIVSTDPITATP-----NEIGKLAVYISCNDIASNGIEPFALTMSVLLPKGTTEEEVELIMKQAGEAAMDLEVEIVGGHTEI--TTAVVRPVIVSTVFGKSLRGESQTCDLMSEGDLICVTKDLALEGTAIIVGDHEDIMSKVLSEDeikqAKSFMDSISVVKDgvlagSIGTHGMHDVTEGGILGAVWEMCMNSKLGAVIYEDEIPLNDITKKVMKYLDVDPLKMISSGSMVMAISKDKKRAMEEAFKDAGIGF--SVIGEIVdEKEGIVLK---------------------
>UniRef50_B8D020(33-319:348) AIR synthase related protein domain protein n=1 Tax=Halothermothrix orenii H 168 RepID=B8D020_HALOH  E=2e-31 s/c=0.48 id=24% cov=73%
------------------------------------------------------------------------GYLAVHVACNDLASCGARPVGIQVVLLLPPATEEIMVGNIMEEITRAAASIEVEVIGGHTEILSK--VTEPIITVTAIGKAPRDKYITTGGARPGDELIITKGLGIEGTFILASDY-----AELLKDRGVPPEIIErgqeyisklsvleegLIGAGLGVHAMHDITEGGLYGALDEMVTASKAGFRIKRSQFPVNPETDIICKALDLDPAGLISSGSMLIAAP--DGGKLVDKLARA--GIKASIIGEITEE-GCLIEDENGE---FEELSGEI-----
>UniRef50_UPI000038DF5E(5-330:343) AIR synthase n=1 Tax=Ferroplasma acidarmanus fer1 RepID=UPI000038DF5E  E=6e-31 s/c=0.42 id=24% cov=90%
------------------ISRKFFEENIINKIGTLRDEVvvppknGVDVGIVKIGDKYMAVTTDPLYIDKSF----GFKKAAWFAFhilLSDLYTSGIPASYMSIDLNLPSSITDNEFKEIWDVINEECIKYNIEVVTGHTARyngVEFPMVGGITLMGTG------EKFITTENAGVGDRIIMTKSCALETALILSntfpeyVRNNIG-EENYKSiigkfytmTCVGEETLAIEYGISERITSMHDATEGGLLNAIYEIGIASGNGLSVDYNKIIIDSDIEKLCNLFNIDPLRSISEGTLLITVKEQYAMEFLTILQS--SGIEASLIGEILDNSK-GIKILKDGKQEDIRPEDDQL----
>UniRef50_B9LTA0(8-327:330) AIR synthase related protein domain protein n=4 Tax=Halobacteriaceae RepID=B9LTA0_HALLT  E=2e-30 s/c=0.42 id=29% cov=76%
-----------------------------------------------------------------------VGELAVHVACNDVAASGADPRWLTHTLFLPDD-DATRRRTVTQQVDATARDLGVAIVGGHTEVLP--SLERPLCSMTALGTT--DRFVSSGGAEPGDRLLLTKGAGIEATAILATDFreacaEAGVSAATLDAAAGFLDEVSVVPDaaavRDAATAMHDPTEGGLLTALVETASASGTVLSVERDRVPVRPETRACCDALGVDPLATFGSGALLAAVPPERVDAVTDALAAA--GIDVGEIGEVraVDDSEGSDDGhlLLDGDRIDEAPRDELYP---
>UniRef50_C5A3X6(1-309:319) Thiamine monophosphate kinase (ThiL) n=4 Tax=Thermococcus RepID=C5A3X6_THEGJ  E=4e-29 s/c=0.42 id=26% cov=88%
-------------MMESEIIELFIR-----HLKRQGDLPLGDDAGALRLGDRWLVATNDMLVRKTDVP--DImtpeqvGFKAVTMNVSDMASMGAEPLGFLFSLGIPGDLDSDYLEGIARGIGEALDFYGLPVLSADT-----NEADDLIIDGAALGITE--RLLTRSGAKPGELVCVTGDLGRALAGYLVWKNGLEVSDAVRkplyEKFLEPRARVREGSELSKVASSAIDISDGLAKELYLLAEMSQVGIEVRPESLPLGKGVEEVAELLGLDPFEIAlasgEEFELVFTVAPEFVES---------LNFDFSVIGRVTRGKGIYLVDDSG-KRVMPKLGWEHL----
>UniRef50_A1HSU1(28-340:346) Thiamine-monophosphate kinase n=1 Tax=Thermosinus carboxydivorans Nor1 RepID=A1HSU1_9FIRM  E=1e-28 s/c=0.41 id=28% cov=89%
----------------DLIQTDAIQEPGTVVVGIGDDAAVL----LPTPRQLQLLTADMLVEGVHFDLGrttaWQLGYKAIAVNLSDIAAMGGVPRHAVISLALPRQIPVEFVVNLYQGMKEICREFRVNIVGGDTVASPHG----LIINVAVMGEVEPTQLVRRSGAQVGDMVAVTGVLGssAAGLDLLSLDNWAEYDFAWPLVTAHLTPRPQVkagqLLGLYGATSM-DDISDGLASEAHEIAKASKVGLRIEAKLVPLAPELKQAAAMLGKEPldyaLYGGEDYQLVFTIGREK----LQALSAVDFGVPLTVIGEVTEAAdGVKLVMDDGVEQ-------ELAPR--
>UniRef50_B5FBG0(7-301:332) Thiamine-monophosphate kinase n=7 Tax=Vibrionaceae RepID=B5FBG0_VIBFM  E=4e-28 s/c=0.43 id=26% cov=46%
-----------------LIDRFFVQ--ENVSRDDVDLGIGDDCAlVTVPEGYQVAITTDTLAAGTHFLADADpvsVGHKALASNLSDLAAMGAKPTWVSLALTLPQS-DEKWLEGFCRGFFDLAKQYQVELIGGDTT---KGP---LSITITVQGIIPKGSALTRSAAQIGDDIYVTGNLGD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6W2L4(5-303:316) Thiamine-monophosphate kinase n=2 Tax=Marinomonas RepID=A6W2L4_MARMS  E=1e-27 s/c=0.42 id=27% cov=67%
----------------ELIQNIFQASVmastqgrGDLLLGIGDDCAQVQ----VPQGQSLVFSMDTLVEGRHFpFDAdpVDIGYRAVASCVSDLAAMGAKPAFFTLGLTIPESDPQ-WLAGLAQGMAELAEPIGLALVGGDTT---KGP---LTITLQVHGYVEPDMAVKRSGAKLGDDIYVTGVLGDAAAAVPIVTGELQVSSE-RFDYfydrywRPQPRLIVGMALKRVVHAMMD-ISDGLAQDIQHILKASGVGANINASRMPISAE----------------------------------------------------------------------------------
>UniRef50_C1TRR7(1-312:343) Hydrogenase maturation factor n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TRR7_9BACT  E=4e-27 s/c=0.40 id=23% cov=85%
----------------------------GPLSRQIGDPSVL-LGSLFGEDVALVDTGSGLVashVDPIVGASEGLGRLAVHVACNDIAAGGIRPRWAQLLVLVPDKGDEDILKDIMEDAVKAAQEISVTIVGGHSGY--TSALSRPLAAVTAFGSAEPGQMVSTGGASEGDIVCVTRGVGLEGTAILAwdYPEECRSKELPEGDIAEARSLADKLsvveealkLASLGATAMHDPTRGGVLEAMCEMAQGAGMSFRIDGDALPISETVDRFSRAFDFDPMRMISSGALVVTLPGEAVERAGAEL---GSIAPLYPVGVVERGTGVTITSSSG-----------------
>UniRef50_A8PLC8(7-310:323) Thiamine-monophosphate kinase n=2 Tax=Gammaproteobacteria RepID=A8PLC8_9COXI  E=3e-26 s/c=0.40 id=24% cov=87%
----------------ELIQRFFnqpMKCRNDVTLGIGDDGAVLN----VPFNQQLVVSTDTFVAGRHFpeetLPE-DIGYKALAVNLSDLAAMAAEPAWILLALTLPH-VDETWLKKFNQGFFSLIQQFQLQLVGGD---LTRGP---LSITVHALGFVPQGKALRRLGAHIGDKIYVTGTLGDAGlaLALMNTPSCCGLtQSQIFSVKQRLhrpHPRVEVGIALRDIASCAIDISDGLMADLHHLLSANQVGAIVQLEKLPLSDSLRGLSPEKAWSlALSSGDDYELCFTVPESKERDLQQQL--ATINTPYQCIGHIKADSGLILLDKKGA----------------
>UniRef50_B6YTL7(1-304:311) Thiamine monophosphate kinase n=2 Tax=Thermococcus RepID=B6YTL7_THEON  E=5e-26 s/c=0.40 id=24% cov=87%
--------------MEREIIELFMK-----YLKKQGDLPLGDDAGALRIGDEWLVATNDMLVGKTDVP--DImtpeqvGFKAVTMNVSDIAAMGARPIGFLFSLGVPRGFDGLYLEGVAKGIGNALEFYEIPVLSADT-----NEADDLIIDGIALGRTRH--LLTRSGAKPGDLVCITGDIGRPLAGLLVWKNDLDVSLSTKeilyEKLLEPRARVKEGIKIGNYANAAIDISDGLAKELHLVAEMSGVRIEVDASKLPIMEEVFEVAELLRRDPLEIAlasgEEFELVFTIPPKYTEE---------LSFDFTVIGTVHKGAGVFITTE--EKRMEVPPIG-------
>UniRef50_O27447(11-313:327) Probable thiamine-monophosphate kinase n=1 Tax=Methanothermobacter thermautotrophicus str. Delta H RepID=THIL_METTH  E=6e-26 s/c=0.40 id=23% cov=86%
---------------KKLISRIISRA--RSVFGSSEVMGLGDDAALIDAGEEFLVLTSDLLLETRHFPDPerprDMGWKTVTVNMSDLAAMGSRPEGFILSVALPD-LELEFFDSLMDGVIEACCHYQAPLIGGDT-----NEADEIILSGTAIGRAEKDMVLMKSGARPGDLVAVTGPLGV-GAAgtelILSGRDTGGFENAVERSLRPVARIEEglILAESGLVSSATDIT-DGLVSELGELMDASGTGMRIYEDRLPLGREVPEIASILGRDPLELAlyygEDFELVFTAPPTGMEELSDMMELH-------VIGEVTVGGGIEMVDKDGVT---------------
>UniRef50_A3DPV0(18-316:339) AIR synthase related protein domain protein n=1 Tax=Staphylothermus marinus F1 RepID=A3DPV0_STAMF  E=8e-26 s/c=0.40 id=18% cov=86%
---------------EKIISKYIHKPLPGEYLDYPDDA-----RDILPISPRILVNIDGYSISSMKLPwrtWSDVGYVAVAGAISDQIAKGAVPRDIMVSLGLPPSMEASIVEEIYKGIDEASRDYNLRLLGGDT-----NSSSTPWISVAVIGYTTAKKPPSRKNAKPGDIVVVTSLYGAMGyVAINGVENAIHKEWVVEATKRPrpfLETAIVIASNYRGVHASID-VSDGLGYALKELSKRSNVRIILEDKPL-YYKELEEICNgntrCLWKYVLNGGEEYGVILTIDPRLSDMIIDYMKKFR--IPHKIIGRVEQGHGLVFEKE-------------------
>UniRef50_B0MTR2(10-289:310) Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM 17216 RepID=B0MTR2_9BACT  E=2e-25 s/c=0.42 id=23% cov=66%
------------------IRDMFAAIPRNGFDGIGDDCTVFPLGS----GESLVFTADLLAENIHFLRRAtsarELGRKSLAVNLSDVAAMGARPIATLLSLAIPHDLPEGWIEDFMEGYRDLSAQYDVGLVGGDTTASDSG----LVVNVTAIGRIADSHIKRRSDARPGDLIAVGGSLGESGAGlrdILAGRYDTPL-AQIHRNPAPQVAEGIWLGERPEVHAMMD-ISDGIASDLRHILHQSGVGAEVDTECIP--------------------------------------------------------------------------------------
>UniRef50_Q57190(7-300:328) Thiamine-monophosphate kinase n=279 Tax=Gammaproteobacteria RepID=THIL_HAEIN  E=2e-25 s/c=0.40 id=27% cov=45%
--------------------DLIKRYFQQQIL--VDDSVQLSIGddcalVSVPENYQLAITTDTMVENTHFLPTIspeDLAYKAVATNLSDLAAMGAQPKWVSLALTLP-NVDENWISTFSQSLLHTLKQYNVTLIGGDTT---KGN---LSITITAQGFVEKNKGICRHKAQIGDLIYVSSTLGD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4J8J0(30-326:334) Thiamine-monophosphate kinase n=1 Tax=Desulfotomaculum reducens MI-1 RepID=A4J8J0_DESRM  E=2e-25 s/c=0.40 id=26% cov=71%
--------------------------------------------------------------------------------ISDVAAMGGYPSHAVVSVGIPEETRVEDIEELYRGLKEMACRFKVNLVGGDT-VKSPGP---LVINIALMGEVEEGRAVFRSGAKPGDLIYTTGFLGTSAAGLYILSHNGDYPVELKEKVirshllpEPRVAAARILSELEGVTAL-DDNSDGLAAELREICRASSAGCLIREKSLPVLPEVEQLACLTGrntLDWiMDGGEDYELLFTLRPERQEYIENALGKEGILYKA--IGIIThSSEGMVLEKEDGAKETI------------
>UniRef50_Q6AKX6(24-315:328) Related to thiamine-monophosphate kinase (ThiL) n=1 Tax=Desulfotalea psychrophila RepID=Q6AKX6_DESPS  E=3e-25 s/c=0.40 id=23% cov=69%
--------------------------------------------------------------------------------ISDIAAMGGLPVHATISLTFTKDTEEAWLDEFIRGLAYMHHRYNINLIGGDTV-----AGERLSITVTLLGQAHKEPVYR-HGAMPGDIIYVGGPLGSAAAGLFLFQNHRDEIETLKDEYASLLrhhlapmpqvELGRALADSDYIGAMQD-ISDGLATDLAHIAKKSAVQAVVFEDKIPVLPEFTRLCKRYQLTATELAlgggDDYLLLFTVRAGREKEVERLARS--VQAMAYPIGLITEGSGVMLKGPTG-----------------
>UniRef50_Q1YU39(3-274:305) Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium HTCC2207 RepID=Q1YU39_9GAMM  E=4e-25 s/c=0.43 id=23% cov=52%
---------------------------------------------------------------------------ALCVNLSDMAAMGAEPRWFTLALTLPrDKAKAEWLAEFSVGLGHIANQYNLALVGGDTTSGP------LTLTLTLVGEVPVDKALTRGGASIGDSVFVTGTLGDgaAGLKIASNKNSNCIDSDrLLQRFYSPQPQIQAGLKLRSIASACIDISDGLLADLGHICKASDVSAVIKAEQLPIAADVQ--------------------------------------------------------------------------------
>UniRef50_C6X363(34-335:364) Thiamine-monophosphate kinase n=6 Tax=Bacteroidetes RepID=C6X363_FLAB3  E=4e-25 s/c=0.39 id=23% cov=82%
-----------------LIKHLTEKFgFDNP---STETSIGDDAAVIDPQNQKVVITTDILAEGVHFnlgyVPLKHLGYKAVVVNLSDLAAMNAIPTQILVGLAVSNRFPVEALEEIYEGIALACKRYKVDLVGGDTT----SSTSGLVMGITAIGLEQSENLIKRSGAKPNDLLVVTGDLGgaylglqilerEHSVYLANPNMQPEMEGydyilerQLKPEART--DIKKTLKELDIQPTSMIDVSDGLSSEILHLADQSKVGFRLYEEKIPMDSLTISTAEELNLNPVMCAMNGgedfELLFTIAPEDFEKI----RNHP---DFSIIGHAVE----------------------------
>UniRef50_D2RH67(29-291:298) Thiamine-monophosphate kinase n=1 Tax=Archaeoglobus profundus DSM 5631 RepID=D2RH67_ARCPR  E=3e-24 s/c=0.44 id=26% cov=75%
-------------------------------------------------GTRLALTTDCLHEK-TDFPKGikpeEIGHLALAINLSDLASCGAKPLFFLYTITLSD-YWIEYFERILKGMKNLADKYGVAVVGGDT-----DFGDELHISGFAIGK--AERFVGRDGAKVGDKICVTGLLGKAQLSLEQLMNGFSrYEIAYPDSLFKPEPRVEEgLRIAKHANSMTD-ISDSLAISLHQIAKRSGVGIKIYEEKIPLDHLTKFVDYEKALElFLYSGGDYELVFTSKKSEYIE----------------IGEVIEDEGVWIVRRDGRVKEVE-----------
>UniRef50_Q8ESJ0(5-305:322) Thiamine monophosphate kinase n=1 Tax=Oceanobacillus iheyensis RepID=Q8ESJ0_OCEIH  E=4e-24 s/c=0.38 id=23% cov=85%
----------------SFIDSIKPTYYRQPSLLKG----IGDDAAVFRSSKDIVTAVDTFVEDVHFSRSTmepyHIGYRALGANISDLAAMGASPSFYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDT-VSGKQ----LTISITVIGYTITNKARYRQHAKEGDIVFVTGTLGDslAGFHILTSDNEnnryvdQDFYIHRHRKPEPRVAFAQALESLDRVSL--NDVSDGIANEASEIAEASNVSIVLRENDIPVAPSFYQFTYEQQYQWkLSGGEDFELLGTVAKGDWAVVNEA--AEKTNTQLTVIGSVVeeEKHPVYIE---------------------
>UniRef50_B3QYZ8(37-334:373) Thiamine-monophosphate kinase n=1 Tax=Chloroherpeton thalassium ATCC 35110 RepID=B3QYZ8_CHLT3  E=6e-24 s/c=0.38 id=27% cov=52%
------------------------------------------------------------------------GAKAISVNVSDICAMNALPTYAVVSIALSEKLSVEMVESLYKGMSNAAKEYGLAIVGGDT----SASTAGLVISVTIVGKVKKEKVARRSTAKPGDVVCVSGVLgGSHAGLKVLMRERKLMLDNLKEDgsvdenyrpeiadyqdavSRHLLPKarldIVRLFERRGIvpTAMID-ISDGLASEIKHICKESKTGAIIEENKFPI-------------------------------------------------------------------------------------
>UniRef50_D1J9H7(13-320:335) Thiamine-monophosphate kinase n=1 Tax=uncultured archaeon RepID=D1J9H7_9ARCH  E=9e-24 s/c=0.37 id=19% cov=70%
---------------ERIVEKFRVDREMVTVGAGDDDCAVIDIEKVRNRFKHLVITTDTLqesTHFPHGISAFQMGWSIVAVNLSDVAAMGAYPFAFTIAMGIPAQTETSFLDELVAGIEKCAASYNTSVVGGDITMSK-----ELILTGTCFGF--ADRPVRRAGAKEGDLICVTGSLGNAALALKLMRGELKVPGDVgvevkKALSQPVPRINEGItIANSGVATSMIDISDGLALSLAEIAKRSSVGVELYEDKVPVlSDEIRS-------------------------------------------------------------------------------
>UniRef50_Q2JTF1(42-315:340) Thiamine-monophosphate kinase n=11 Tax=Cyanobacteria RepID=Q2JTF1_SYNJA  E=1e-23 s/c=0.41 id=20% cov=51%
---------------------------------------------------------------------------AVAANLSDLAAMGSRPRALVVGLGLPGSTPVAWVEELYEGMRACCARWGAELVGGDLCRSPQR-----FVAITALGSVQPGRAIERRRAQPGDWLVVTGPHGDarAGLELLLHPEQgssataAQRQQLIRAHQYPrprldVLSLLEALPGPLRLAGM--DTSDGLADALVQVCQSSGVAARIAAERIPIS------------------------------------------------------------------------------------
>UniRef50_B8KML1(18-337:366) Putative thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium NOR5-3 RepID=B8KML1_9GAMM  E=2e-23 s/c=0.35 id=21% cov=90%
---------------ERFIKARIMDRIRSsvDKGSGLVGGLGHDAGVLresLLPNERLLVNTDRSGVSkayTLGLAGGEcIGDFAVSHAVSDILATGGIPFAVSVAMLLPGSTSVKLVDEIVDGIVEACAEFDVTITGGDTK-----KAEKLSLVVTALGRASEDRLLFRDTPKVGDQLVVSGFLGSMLMGSIIHKRHHKVSELIQKLVdealvrqRPPYRLAMEMGAARIATACTD-ISDGLPSACRNMVEKSNLGVELFADNIPIHPALESLLKTLSLTPLQLSMAGgdwQFLYCMPKASIASLNRI--SDSCGTPLTVVGEVTGASGVWTRSKCGRRRKV------------
>UniRef50_B0TDV9(49-363:373) Thiamine-monophosphate kinase n=1 Tax=Heliobacterium modesticaldum Ice1 RepID=B0TDV9_HELMI  E=2e-23 s/c=0.36 id=26% cov=74%
------------------------------------------------------------------------GRKALAVNISDIAAMGGIPAWAFLSIGVPASAKVEEVEGLYAGMGEMAAQFGVELAGGDTV-----RSDKWVINVTLLGLAVK-APIGRSGGRPGDLILVTGTVGDAAAGLHLLLMETKMSQAEKMDAQmreapigeadrqalllrHLDPIprvaeARALVDYGGVTAMMD-VSDGVSSEVHHLCRNSGCGARIDLANLPISPAVRRLARREGREvfawALSGGEDYELIFTAPEERVPGLIDHVRRET-GTGVTVIGRLTDGTAGVMAV------YPDEMGGDAVP---
>UniRef50_D1A2J3(42-344:352) AIR synthase related protein n=1 Tax=Thermomonospora curvata DSM 43183 RepID=D1A2J3_THECD  E=4e-23 s/c=0.37 id=27% cov=70%
---------------------------------------------------------------------------------SDIAAMGAQPIALLSVVRYPKTMPDERFAQVLQGINDACARVGAPNVGGDI-----GTAERLILSASAVGVVEAGRSLLRGGARPGDRLCITGPTGVAAAAqkyfgkldVADTRlspqaEELLLNAWKRP--QALVPEGRSLSTSGLVTSCQD-SSDGLKAGIESIAARSGVGFTVEEDALPVVGAVEEVAKLSDteLTPLLLGDsvDFQLIFTVPEEHVEELQEIFAAH--GHSAFhDIGFATEEPDLLLRGSDGITRRLP-----------
>UniRef50_C8R1R1(47-327:341) Thiamine-monophosphate kinase n=1 Tax=Desulfurivibrio alkaliphilus AHT2 RepID=C8R1R1_9DELT  E=8e-23 s/c=0.39 id=26% cov=73%
------------------------------------------------------------------------GRKAVAVNMSDIAAMGGTPRYALLSLGLGEAENPAWLEMMLDGLAEAVAAYGAVLIGGDTVKSP----ERLLLTVTIIGESPASRACLRSGGQAGDSIWVGGPLGLAAGGLELCRRDLAADPQWQEAVqAHLDPPAQVelgrrLAAAGVVHAMMDL-SDGLATDLAHICAASGVGAEVEAELLPVPDLLHRAAAVCQADPLNWAlcggEDYRLLFTADPAR-DGAIAELGRDLADTTLTRIGRLTapppGGPGVLLRTADGQSR--------------
>UniRef50_C0ZK37(65-310:338) Thiamin-monophosphate kinase n=1 Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZK37_BREBN  E=9e-23 s/c=0.45 id=22% cov=54%
----------------------------------------------------------------------DIGYKAVISNVSDVAAMGGVARYALVSIAVSPQWTPDECQQIYEGIYEACQAYGVRVIGGDTVSAP----DALHLSVTVLGEVEKGRAIRRSQAKPGQLVFVTGHVGTSAAGLHLLLQGETAERGVSASWETLMDAHQrpvaqikagrLLLESGACSALND-VSDGLASELWEIAEASGVSILVDAATVPIHDEVR--------------------------------------------------------------------------------
>UniRef50_Q2RZV6(15-323:360) Thiamine-monophosphate kinase n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2RZV6_SALRD  E=2e-22 s/c=0.35 id=27% cov=70%
------------------IGEFGLIALLRDTLGEPTDDTIVsgiadDAAVYRTDEDRVhVMTTDTLVEGVHfdraFMPMEHLGFKALSVNVSDVVAMNASPRYATVSIGIPQNVSVEMITTVYEGLKQACDAYDMHIVGGDT-----NASHGLSLSISVVGAAAEEDVVYRTGAQVGDKICVTGDLGSsyAGLKVLLRnRERLqEQEEDFEPDLDPYSYVIRRhLAPPAQLKTVRDwgdagvqphaliDISDGLSAEVHHICEAGDLGAQLYEPALPIDPETR--------------------------------------------------------------------------------
>UniRef50_A8L3S7(47-291:375) Thiamine-monophosphate kinase n=48 Tax=Actinomycetales RepID=A8L3S7_FRASN  E=3e-22 s/c=0.44 id=24% cov=57%
----------------------------------------------------------------------DTGRKAAAQNLADVAAMGARPTALVVGFAAPGELPVAWAEQLADGLRDECALVGASVAGGDV-----SSAAGIVLGITALGDLAGRAPIRRDGARPGDRVVLAGRIGwaEAGLALLRAtelpPEILRAHAEVVDAHRRPHPPytLGPLLAAAGAHAMCD-VSDGLLADLGHVAAASAVWIDIDPTALPVPGPIRDAAAVLGADPL---------------------------------------------------------------------
>UniRef50_Q5FNA0(18-312:325) Thiamin-monophosphate kinase n=1 Tax=Gluconobacter oxydans RepID=Q5FNA0_GLUOX  E=4e-22 s/c=0.37 id=23% cov=84%
------------------IARHFRPLAGAESLDLRDDCALMRC----PEGEEFAISTDTMVENVHFLPDDppeTLGRKLLRCNLSDLAAMGARPHAYTLNVTVTRGgrHDENWFAAFSRGLAEDQQRYGVHLIGGDTTSIS----GPLVLSATVFGLLRHNTALRRSTARPGDEIWVTGTIGDAALGLLVLQGSLQDPSGFLAERYHLPRPRTGLHLHGIVSAAMD-ISDGLIQDCGHIAEESGVQLVVDAEAVP----VSSAAASLGHEWLMrrlcGGDDYELLLTCAPERSAALQAACQAAEV--PVHRIGTVRTGSGVRL----------------------
>UniRef50_C3K2R7(5-304:321) Thiamine-monophosphate kinase n=3 Tax=Gammaproteobacteria RepID=C3K2R7_PSEFS  E=4e-22 s/c=0.36 id=22% cov=87%
----------------ELIRNYFAAAPCAQGGEGIALGIGDDCALLAlPTGEQLAISTDTLVAGVHFADPCDpflLGQRSLAVAVSDLAAMGAHPLAFTLALTTPT-VDADWLQRYAQGLNAMAQRCGVGLVGGDTTRGP------LSLTLTVLGRVPAGQALTRSGARPGDLLCVGGELGNAAGALPLVLGQRSADAAIAdPLLAHYWSPQPQLalgLALRGKATSAMDISDGLLADCGHIATASQVSLLIERQRLPLSTALLAFVgdDEARVAALSGGDDYVLAFTLPPAELAPLLAD------GLPIHVIGRVEPGQGVTLLDADG-----------------
>UniRef50_C6LD50(63-354:362) Hydrogenase maturation factor n=1 Tax=Bryantella formatexigens DSM 14469 RepID=C6LD50_9FIRM  E=4e-22 s/c=0.37 id=24% cov=73%
--------------------------------------------------------------------------------VNNLACAGSEPEAVLLTVLLPENTEEAFLKEVMREAEAVCKELGIQIAGGHTEVnpavmlplltvtalgaAPSGATTSKAIapratpsgeaasgaATSGVhGAGAMDSYLRAAGAQPGMDVLIAGTVAREGTALLAWAHEEELKKRFPADFveqaESFGSSISILQAARvamqcGAAALHDASQGGIFGALWELCEGAGCGLTADLRKIPIRQETIEICEYFGYNPYCLLS-GGALLVVAPDGRRVEMELAR---HGITAAVIGKLTDSNDRILLNG-EERRFLDRPAQD------
>UniRef50_Q1N2P0(1-269:305) Thiamine monophosphate kinase n=1 Tax=Bermanella marisrubri RepID=Q1N2P0_9GAMM  E=4e-22 s/c=0.40 id=24% cov=69%
--------------MNEF--DMIKQYFQDPQLHFPHPNVRFgigdDCASILPDENHeLVFSMDTLVDGVHFLqtsNSFDIGTRALCVTLSDLAAMAATPIGFTLALTIPEAHS-TWLQGFSQGLAEIAQRFHCPIVGGDTTRGPH-----CVITIQVHGQVKKGKALMRSGAKPGDKVFVSGDLGD-GAGALSQVLENPLDSTGLAQryFQPL-PEIEFAQAIQSYATSGMDISDGLLQDLEHICRASQVGMMIDPESIPMSAD----------------------------------------------------------------------------------
>UniRef50_D1B5R8(37-304:326) AIR synthase related protein n=3 Tax=Synergistaceae RepID=D1B5R8_THEAS  E=5e-22 s/c=0.40 id=27% cov=68%
------------------------------------------------------------------------GRLLVRVNANDVAAKGGEPMFLAVTMIIPPSMGVEAASAIMEEIHRECCRIGVAVAGGHTEFNDR--YDSPVLMGAMIGS--AQRVLSASEVRPGHLVLVTKHLGIEGMSILAHDREdlLGFLSgeeleEVRSwgELTSVVPEAALLRDLAS--FMHDPTEGGFLGGLGEVESLTGLKVRL-EGDLPIHPLTRRAASQLGFDPTCLISSGSLLAFLPPKGLEEAERRLHRA--GIPWSVVGEVLDEP--------------------------
>UniRef50_Q8TXQ3(38-300:309) Thiamine monophosphate kinase n=1 Tax=Methanopyrus kandleri RepID=Q8TXQ3_METKA  E=5e-22 s/c=0.41 id=23% cov=65%
----------------------------------------------------------------------------VASVVSDVGAMGGEPSFFGFSVCLDDEV---DVEQLVLGISEGLREFGVSLIGGD--VVE---GEELVLSGTCLGKL-KGEPLLMSNARPGDVVAVTGPLGGPNAFVRAILNGMEPEETLYERFARPRPPVEVGVELarGGYRAAVTDISDGLLAEAEAIARRSGVAIEIHTWKVPVDEGVEEVAQEFDVDPVDLALEGgedyEFLICGPEDVVKEF-----------GLTTIGRVTEGEGVRI----------------------
>UniRef50_B8D469(6-317:340) AIR synthase related protein domain protein n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D469_DESK1  E=8e-22 s/c=0.34 id=23% cov=89%
--------GSLGEMGEEAVINLIADKLISKPESGESLTYPDDARDLLPKGPRLIYSMDAYRIKSLMLPwrtWSDIGWMALTGALSDVVVKGGVPSVAMIGLGLSSETDILDLEELVKGLREASNYYDVRITGGDT-----NESLDPWIAVSVMGFTTCKRPPSRRGARPGDIVIATGSYGSMGFVALHGVVEASGISWVVDNTKRVYLKLEVanviMSTYRFIHASMD-VSDGLGYTLEQLSELSGYGILL--ENLPVHPaGLREYCknsiECMWRHVLVGGEEYGAVLIVAGEYLDKVAEEL--DYYEIPYSIIGRVGNiSPGIYINGA-------------------
>UniRef50_C9RLV8(76-321:328) Thiamine-monophosphate kinase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RLV8_FIBSS  E=2e-21 s/c=0.43 id=27% cov=71%
--------------------------------------------------------------------------------VSDVSSMGGRPKIALFGLCVNKNWSEETRNRIAKAVAQGFERRGITLIGGDTV-----SGDVGMFSTTLLGTTDGEISLLRSDAKPGDHVFVAGTLGksDAGLWILMNhpEEANRFPRLVEYHLAPkICEDAGAQLVKQGVRGACMDISDGLSSETNHLALSSGVSIEIDEQKLPIDPDVLEMCEYFGLSPLQFAlnggEEYELLFTSNLTKSI----YLEGAPKMGEIHDIGLVSCGNGVYLKGQDGVKALLN-----------
>UniRef50_C6QHP2(41-341:341) Thiamine-monophosphate kinase n=1 Tax=Hyphomicrobium denitrificans ATCC 51888 RepID=C6QHP2_9RHIZ  E=2e-21 s/c=0.35 id=25% cov=81%
-------------------------------------------------GSDLVFSSDPIIAGVHFFhddRPADIAWKALACNASDMAAKGAAPVAYLLTLALPEAPERDWIAAFADGLRAAQSEFGCKLIGGDTDVTP----GPLSIGITIIGSVAAGAFIPRGGAKAGDHVFVSGTIGDAALGLALRRDPSQFST-LTDDQRAL--LLDRYLRPKPRLALAGPVRsharsaldvsDGLIKDLRRLAGAS-LGIAVKFDDIPLSPPARAA---LAANPnvrdsiLAGGDDYELLIAVAPENIEKFVTS--AGESGIRVHDIGVLESKITTVVLDPSGVPIALRRPGYDHFSR--
>UniRef50_A0L3Z7(15-322:338) Thiamine-monophosphate kinase n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L3Z7_MAGSM  E=2e-21 s/c=0.34 id=27% cov=85%
------------------IQHIFAPiqskQGEGVQLGIGDDAACL----VVPRTQDLLATTDTMVEGIHFSSDADpylLGQKALAVNLSDIAAMGGLPRWYLLSMAVPNRTSQSWLEEFARGVKAASEMFHVALVGGDT--VRSNA--KIVITVQMLGLIGQHRAVARSGAQVGDRLYLSGTLGD--SAFGLAHLLGKLPAMLADDVSYLSrrhhlpePRIQlgmALQDAALAHACID-VSDGLLADLQHICEASQVSAVVDVEKLPFSESAQRVIAQYGRSALELAltggEDYELLFAISPGAADQVEKIV--HQVGVSLVEIGEVVgvgERPGVVVR---------------------
>UniRef50_A1AW74(5-294:309) Thiamine-monophosphate kinase n=2 Tax=sulfur-oxidizing symbionts RepID=A1AW74_RUTMC  E=3e-21 s/c=0.36 id=21% cov=69%
----------------SLIETYF--NWGGSNLANL--GIGDDCAVIDIDANYqLVTSVDTF-IEGVHFPsntsASDIAYKSLAVNLSDLAAVGARVKYFTLALTLP-NINKKWLSQFSTSLKSLADEFGIVLVGGDTT---KGMLS-ITINVTGV--VKKNKALLRSSAQVGDLIFVSNTIGDAAYAWKQLQNNQTPSEYVINQFNRPKPQLFLGQQLSDIANACIDISDGLEQDLTHILTRSNVGASINLDDIPLTYEVKTYIE----------------------------------------------------------------------------
>UniRef50_B9ZS01(9-311:324) Thiamine-monophosphate kinase n=1 Tax=Thioalkalivibrio sp. K90mix RepID=B9ZS01_9GAMM  E=6e-21 s/c=0.34 id=27% cov=87%
----------------DLIRRYFAEPAGtspDVRLGIGDDAALL----GVQAGHELVVSVDTMVEGTHYFPDhppASLGHKALAANLSDLAAMGADPLGAVLSLTLP-SVDHDWLAAFSRGFLALAEQASVPLVGGDTT---RGPG---AISVTVLGQVPAGQALRRAGARPGDRLVVSgaLGGAAAGLAFEKQRRAQGRPPDEESpDCARLFWPSARLALGRGLRNrarAVIDISDGLLADLGHLAAACGCGARVDWSQLPVDPLLEGQPEEMVRDcVLAGGEDYELLFALPPTEPLELLSLSVRTSL----TVIGEFTSGSDIEVVDAHGAR---------------
>UniRef50_D2M233(41-309:327) Thiamine-monophosphate kinase n=1 Tax=Bacillus cellulosilyticus DSM 2522 RepID=D2M233_BACS4  E=1e-20 s/c=0.38 id=25% cov=52%
-----------------------------------------------------------------------IGHKALAVNISDIAAMGAIPQYYLVSIAIPKtSWKKKELNDIYNGMNELATVWSMDLIGGDT--VSTN--DALVISVTVIGKVEKERRLLRSNARCGDVVFVTGELGlsAYGLQALLEKGYENIDDDellpyLQAHQKPdPHVRAGRLLANCGYRIALNDISDGLASEAKEIADASQVTVELDWAAIP--------------------------------------------------------------------------------------
>UniRef50_Q8K9A5(7-298:323) Thiamine-monophosphate kinase n=4 Tax=Buchnera aphidicola RepID=THIL_BUCAP  E=1e-20 s/c=0.35 id=21% cov=45%
----------------EIISKFFKNHQkkdKNQIKGIGDDSALIK----IPKNNLLAISTDTLVEGKHFLKNItpkDLAYKSVAVNLSDLAAMGAKPTWITLSITMPKS-DSVWLKSFSKSFFKILNKYKLNLIGGDTNSGP------LSITLSIYGLIEGKNALLRGNAKNGDLIYITGNLGE--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7ALQ7(5-93:93) Putative uncharacterized protein n=1 Tax=Parabacteroides merdae ATCC 43184 RepID=A7ALQ7_9PORP  E=2e-20 s/c=1.15 id=44% cov=26%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPIPDAVRGASEILGLDPLHIANEGLVLVILPDEKTEQALAVMQNYPEGKNAAVIGCIQEKGYalVKMKTLYGNYRIVDMLSDEQLPRI-
>UniRef50_B5JUN1(9-283:305) Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium HTCC5015 RepID=B5JUN1_9GAMM  E=3e-20 s/c=0.37 id=21% cov=66%
--------------------------------------------------------------------------------LSDLAAMGAKPAWVSLALTLPE-ASEVWLRGFASGFGALAAEYGVALIGGDTTRGP------LSVTLTVTGFLPESQALLRSGAQIGESVYVSGRLGAAAQELGQVLQGGSLSPDQRRHLDYPQPRVELGQQLLPVASSAMDLSDGLLSDAAHLAAASELAVDIDLSRLPLAESLASLPRE---EAWALASAGddyELLFTAPNVESPR-LEAL-SQTLGLPLTRVGRTREGDGV------------------------
>UniRef50_UPI0001BC315E(57-309:311) hydrogenase expression/formation protein n=1 Tax=Butyrivibrio crossotus DSM 2876 RepID=UPI0001BC315E  E=3e-20 s/c=0.40 id=22% cov=72%
---------------------------------------------------------------------------AVYKAANNIWVSGGELLGIEASFMLPKNYNEYNLKAYTKRVKAACDKCKTTLAGGHTEVTDGVKRFCISVAATGIaGTTPVNI----HNVKPGMDIIVTKWIALEEAAMIVSNEDNmaklceHFSNEYMSVTgqYADWLTVRdeaAVAMKHGVAAMHDISEGGIFTALWDFAEGSGCGFEVDLKRIPLRQETVEIAEFFHLNPYTMKSSGSIIIACDNGT--DMVNAL--NEEGIPAVIIGRTTDNNGKILRNEDEI-RYLD-----------
>UniRef50_A0LIX8(10-316:340) Thiamine-monophosphate kinase n=1 Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LIX8_SYNFM  E=3e-20 s/c=0.33 id=24% cov=68%
----------------ELIRRIgtFLPGPPGDVVVGIGD----DVAVLNVSGPEYLLATcDAQVENIHFIRAATtpyqLGRKIVAINVSDIAACGGRPKWALVSLALTPDTGVDFVDGLYAGMQEEIHAAGASIVGGNL----SGIRGEIVIDLSLLGTVSPECLILRNGARSGDLVLVTGTLGESRAGLeLILRPELEVEQEAgdRVRARHLTPGARLregriLAATGSIHAMAD-VSDGVLGDLGHICRASEVQAEIWPESLPISPE----------------------------------------------------------------------------------
>UniRef50_B4U7Q4(16-288:306) Thiamine-monophosphate kinase n=3 Tax=Aquificaceae RepID=B4U7Q4_HYDS0  E=4e-20 s/c=0.37 id=22% cov=57%
-----------------------------------------------------------------------IGFKAISINVSDVVANGGKPLYGLISLMIPEDIDERFIERIYEGVKSACDFYKLRIVGGNVSKASKLGID-VFL----IGEIDRFVSRAGANV--GDDVVVSGTLGDsyTGFRLLTTKKEYE-DYELRLIERHLRPtaRIDYINHIRKYASACMDISDGLSSDLWHIAERSNVVIEIDLNKIPISRELRLYASKENLNPYDIA------------------------------------------------------------------
>UniRef50_A1K2S2(25-327:336) Thiamine-phosphate kinase n=9 Tax=cellular organisms RepID=A1K2S2_AZOSB  E=4e-20 s/c=0.33 id=25% cov=86%
-----------------LIQRHFSRPCGHTALAGGDDAALLH----PRPGMELAVSADMLVAGTHFFPDAdphDLGWKTLAVNVSDLAAMGADPRWALLSLAL-PAADDAWIAAFADGFYACAERFGVDLAGGDTTRGP------LTLSVTILGEVPRGQALTRAGANAGDDIWVSGQPGLAALGLEMLRGTFAPTADGERCLAALHrpqPRVALGQALRGLASAALDISDGLLGDLGHILVQSRCGATLHEDALPLaalyatgaSPALARRCLLAGGDDYEL-------LFCAPPAARAAITAL-GPALALPLTRIGTLSDAPGtVALRSADGTLTAL------------
>UniRef50_O05514(61-248:325) Thiamine-monophosphate kinase n=5 Tax=Bacillus RepID=THIL_BACSU   E=5e-20 s/c=0.54 id=21% cov=54%
----------------------------------------------------------------------DIGYKALAVNISDIAAMGGIPKFYLVSLAVPSKWTESEIKAMYEGMNELAKLYHMDLIGGDT----VSTADKLVVTVTVIGEIEKGQACLRSLAKPNDIVFVTGEIGssAAGLSLLLEETNPQ-NSSVETDyFIHRHKRPEPRVSVGRLcsifkRAALNDVSDGLASELNEIAEASCVSIEIVESMLPIHSD----------------------------------------------------------------------------------
>UniRef50_A6CFS7(25-299:307) Thiamine-monophosphate kinase n=1 Tax=Planctomyces maris DSM 8797 RepID=A6CFS7_9PLAN  E=1e-19 s/c=0.36 id=22% cov=68%
------------------------------------------------------------------------GRKALAVNLSDIAAMGGSPHSALVSLALPRSRGSEFAKSVMQGIMELAAEFQTQLAGGDT-----NSWNGpLVINVAIIGTADQSHSIKRSGAQPGDWIFVTGALGG-----SLESHHLTFQPRVREAVA--------LMETVTIKSMID-VSDGLASDLQHILVESDVGAVIQSKQIPISPRVSS--ELTDAERLQKAlSDGedfELLFTVSAEQGQRLRD---QNPLSIPLTHIGKITAEQGALLQQTDGSTTPLE-----------
>UniRef50_C7R8N3(5-304:323) Thiamine-monophosphate kinase n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7R8N3_KANKD  E=1e-19 s/c=0.33 id=24% cov=47%
----------------ELIKEYF--SFSQSKSDTVVEGIGDDCAVLSVPDKRqLVTSVDTLVDGVHFFSDsdpADIAYKSLAVNVSDLAAMGAKPLGFTLAIALPK-VDEVWLKSFSKGLQEASADFEIPLIGGDTTQGP------LTITVNVLGSVKADKAMLRKSAQLDDDIWVTGYVGDAAAAL---------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B4WXS9(34-321:333) Thiamine-monophosphate kinase n=1 Tax=Alcanivorax sp. DG881 RepID=B4WXS9_9GAMM  E=1e-19 s/c=0.35 id=28% cov=65%
----------------SLIRRYFHHRQGDtVVLGPGDDGALL----VPPAGQQLVMTQDTSLVDRH-FPAdmapADVGYRCLAVNLSDLAAMGANPLWFLLSLTLPE-VDEDWLAEFSRGMFELADQAGISLVGGD---ITRGPL-AVSIQAT--GSVPPGLALRRDGARVGDQICLGGVTGagllgleqwqagqRHGPAIGHFRR--------------PRPQWELGMALRGQASACIDISDGVLADLSHILQASgGLGACLDEAALPEDPPVLAGC-----------------------------------------------------------------------------
>UniRef50_D1BMW6(46-316:326) Thiamine-monophosphate kinase n=3 Tax=Veillonella RepID=D1BMW6_VEIPT  E=1e-19 s/c=0.37 id=22% cov=69%
--------------------------------------------------------------------------------LSDVAAMGGIPRQIVLSLAVSDHIDTAILDEIYRGIKDQCMRYQLNILGGDT-VRTEGPM---VWTVTIIGEIPKGTAVMRSGAKVGDVVGLTNYVGYAATGLGALSYNLvGYDMTKVGHQRP-EPQIElgQKLRLLGIHSMND-ISDGLGSELNEIAVASNVSIVFEEQAIPLHEETYELAKHLQTNPvdyaLYGGEDFQLVFTAPKSLLSE-LEKLAGITL------IGEVLSGpPRVQMVTLDKTIKTIE-----------
>UniRef50_B7JUY6(30-317:344) Thiamine-monophosphate kinase n=4 Tax=Cyanobacteria RepID=B7JUY6_CYAP8  E=1e-19 s/c=0.35 id=22% cov=80%
----------------------------------GDDGAILS----VDPAQKLVVTTDVLVDGVHFsdrtTPPATVGWRAAAANLSDLAAMGANPIGITVGLALPGEVPVNWVETLYQGLNDCLQCYDTPIVGGDICRSPT-----ITVSITAFGTVLPHRIIRRSSAQPGHAIVVTGThggsrgglelllnpqLGDH-LTITEQQALIETHQRPQPRLDVLPHLWEIVG-TTEVAGM--DSSDGLGDAVVQICRMSGVGAKIERSQISLPPSLLAlVSPEQALQWgLYGGEDFELVLCLPFDLAKTLVERL-----GNGANIIGEITTEPRVILIDSNG-----------------
>UniRef50_C9LRA0(31-270:329) Thiamine-phosphate kinase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LRA0_9FIRM  E=2e-19 s/c=0.41 id=23% cov=50%
---------------------------------------------------------------------------------SDMAAMGAEPVSFVISAALPGDLSITWIESCYDGIRECCREYSVNLLGGDIT----GSKQGVILTGTIVGIVPENQAVKRSGAKEGDIVFVTGTLGDssAGLSILLdgKKEEYPMLAIRHQRPKPQIDFGRILRES-GASSLND-VSDGLSREINEITSASRVTIELEKERIPLSDE----------------------------------------------------------------------------------
>UniRef50_Q5WJP9(63-321:330) Thiamine-monophosphate kinase n=3 Tax=Bacillus RepID=Q5WJP9_BACSK   E=2e-19 s/c=0.38 id=20% cov=74%
-----------------------------------------------------------------------IGRKALAINVSDLAAMGAVPQFYLVSIAIPPNWSAEELTSLYEGMRAVGDRYGMDLIGGDTVSIK----DSLVLSVTAIGRVKKGCALFRNQAQPGDVVFVTGPVGgsAAGLELLDQRGRFGAFTEQERRYVHMHqepvPQVEmgKMLAEQPYRVALNDISDGLASESMEIAEASGVQLVLDQQKVlELSPQMDSVLPEKRVKWsLNGGEDFQLVGTMTDSAFSSCCEA--AQQQGRHLYKIGFVRAGEPAVLLASETGEQALQM----------
>UniRef50_UPI00016C3B48(16-282:303) thiamine-monophosphate kinase n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C3B48  E=4e-19 s/c=0.37 id=25% cov=64%
-----------------------------------------------------------------------VGRKAMAANLSDIAAMAGVPTAATVSLALPNSHGADLARELFLGLRDVADAFNVPIVGGDT----NSWAGSLVVSVTALGEATVRGPVRRGGARPGDWIFVSGPL---GGSILG--HHLDFTPRV-AEALQLHELVE-------LRAMCD-ISDGLSADLNHICEESRCGAVLDGDAVPITDAARELSRTSGRTPLQHAlGDGedfELVFTVSPEDGTKLLA---RRPFPSLAK-IGECVE----------------------------
>UniRef50_D2MI54(4-248:278) Thiamine-monophosphate kinase (Fragment) n=1 Tax=Candidatus Poribacteria sp. WGA-A3 RepID=D2MI54_9BACT  E=4e-19 s/c=0.40 id=23% cov=60%
--------------------------------------------------------------------------------LSDVAAMGGTPLYVLVSIAVPVRTPPKNIRALYRGLQDACAPCNVELIGGDTSSSP----SHVFLSLTIVGSVRANRALTRHGAEVGDRLYVTGTVGDanAGLRILqshsnnlrrfspSAAEKFLIRRHRRPT--PRIQVGQLLVDRNLAHAAIDL-SDGLSSDVGHVCEESQVGAEIRGEALPLSSPLRAFAKRHDLDPMELALQGgedyELLFIAPAKHHQKVL------------------------------------------------
>UniRef50_Q2RJB8(11-328:337) Thiamine-monophosphate kinase n=1 Tax=Moorella thermoacetica ATCC 39073 RepID=Q2RJB8_MOOTA  E=5e-19 s/c=0.31 id=26% cov=90%
-----------------LIERLKAGAIVDP--ARVVMGIGDDAAVLKGEPGFLTLaSTDMLVEDIHFTLATatprEIGYKTMAVNVSDIAAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFGVNIIGGDTVSSPR----AMVINLAILGRVENDACLYRHGAQPGDILLVTGDLGGSAAGLDTLLSPRPAPAEVIAWARARHFRptprvveIRAALKAGGLTAA-DDISDGLVAEVYTLATASRVGIVLEAGAIPIAPATRQLAAIYHKEPLDYALYGgedfELLLACRPDKVDAVREAVNRACR-TPVTVIGRVVPAEEGITINHSG--RVLPLTPG-------
>UniRef50_Q3ARA0(9-336:369) Thiamine-monophosphate kinase n=11 Tax=Chlorobiaceae RepID=Q3ARA0_CHLCH  E=6e-19 s/c=0.30 id=25% cov=87%
-----------------LIDTI--AHLVQPTLANaptLLQGIGDDCAIMQPTAGMVeVATTDLLVESVHFdlltTPLSHLGSKAISVNVSDICAMNALPRYALVSLALPPTFSKKMVEELYGGMVHAAQAYGIAIAGGDT----SASRSGLMISITAIGEALPTQLTRRSGAQLDDLLCVTGTLGGsmAGLKLLMrekeimlehLRNNEPVNRNLLADLdeyrelmqRHLLPTarldVVRLFHRLGIqpTAMID-ISDGLSSEVQHICRHSNCGALLHESRIPIHATTRQLADEMQEEPLTWAltggEEYQLLFTLPEATYQQL-----AHE--RDIHVIGTITPtNEGMVLEEMFGIR---------------
>UniRef50_Q6L0S9(11-303:315) Thiamine-monophosphate kinase n=1 Tax=Picrophilus torridus RepID=Q6L0S9_PICTO  E=8e-19 s/c=0.33 id=18% cov=70%
--------------------------------------------------------------------------------LSDIAAMAGRPIGIMVSYSVNPDLDIRDLKAFHDGIKKQMNRFNAKILGGDTK-----EGEDFTVSGTIIGIQEGSLVRRRSDIKPGQKVYVTNDIGRSSSGFLFYKNNYKRDLGI-SLMMNVEPRINEAIKIsqSGAMFMMDL-SDGLAASFYQIRNDYKTGFKIYYERIPKSMYVREASKISGVDEkeiiLSGGGDYELLFSVPYDTSEAFERSMSLNNINVSC--IGETYDGANIInMDGSWEELR--------------
>UniRef50_C5S8T0(29-312:317) Selenide, water dikinase n=3 Tax=Allochromatium vinosum RepID=C5S8T0_CHRVI  E=9e-19 s/c=0.34 id=28% cov=73%
----------------------------------------------------LVTTVDAFtpVVDDPF----DYGRIAAINSLSDIYAMGARPvSALSVAGFPDTRLPLDVLAEVLRGLVAGAASVGVPVLGGHT-VKNPEPLFGLAVT----GVIHPDRILRKGAGQAGDVLVLTKPLGIGVLTTAIKNERLGAEGlrRVTELMLTANARAAEIMVEQGARAATDITGFGLLGHLLEMVTGAGVGAELRFDAVPVLDEafelarqglfpggartnLRAYSERLEFDPaleewqrLLLTDpqtSGGLLITFAPEQAEDALAALQTA--GVPATIIGRLV-----------------------------
>UniRef50_C6CVI9(24-337:349) Thiamine-monophosphate kinase n=1 Tax=Paenibacillus sp. JDR-2 RepID=C6CVI9_PAESJ  E=1e-18 s/c=0.31 id=24% cov=71%
----------------------------------------------------------------------DIGYKALASNVSDIAAMGGVPLQALVSVSVPKQLGPEPMHRLYDGLYACAEQYGVAVIGGDTTSSPQ----HLVVAVTVTGAVEAGKALRRSGAKPGDAVVLTGPVGksAAGLHFLLAQRERGADalageraaAQLVQAHRRPSPSVRAgrLLLARGTCHSLNDVSDGLASEAWEIAEASGLVVSLFEKHLPRSGSMAAYAGVAGIDPlewmLYGGEDYVLLGTMEQGDAAAAQAAFHAEGLpfyiigeasaGAPAAEIIRVTDRG--------------------------
>UniRef50_Q54757(23-307:327) Thiamine-monophosphate kinase n=9 Tax=Cyanobacteria RepID=THIL_SYNE7  E=1e-18 s/c=0.34 id=22% cov=68%
-----------------------------------------------------------------------IGWRAAAANLSDLAAMGATPAGITLALALPSDRRLSWLQQIYQGLDRCLKQYDCPLIGGDLSRSPTAT-----LAVTALGWVNPNRVIRRSTAQVGDWIMATGT---HGLSRLGLGHLLGEWTLAEPlrdqaiaahqapkprlDVVPLLARSQPAGTVWRVAGM--DSSDGLADAVLQICRASQVGAVI--EALPLPATTSFDRDRLIQAALYGGEDFELVLCLSPDWAQALLELL-----GEQAQVIGQITEKPVVQLR---------------------
>UniRef50_A1RXF5(1-299:312) Thiamine-phosphate kinase n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RXF5_THEPD  E=1e-18 s/c=0.32 id=25% cov=81%
--------------MPELREDVVVDKVTSLLGLRKDDAAVLSL-----EETSLVVNVDSFESGIHlypFLPPRIAGRRAAVGSISDVLVKGAKPLGILVSLRVPSTADLGFLEEFYRGLLEAGTRFGARILGGDTDV---SSTCYLRVDVVAIG-VSRGKVLHRWGAKPGELVAITGRVG-----ISSVLYALSSGGALS--CNPGNSLVEEYgwgqlpepatwLGIKELLTSAIDNSDGLALSLYYLAESSGVGIVVEE--LPVH-AVAKEClprERL-VDAVLYASgeDYNFIFTFPEEAEEEVRK--------TGATIIGRVTEGEGVFL----------------------
>UniRef50_A4A6E1(3-301:310) Thiamine monophosphate kinase n=2 Tax=unclassified Gammaproteobacteria RepID=A4A6E1_9GAMM  E=2e-18 s/c=0.32 id=23% cov=85%
----------GGKQPRDefsLIARYLkeLDRGPAVVVGNGDDGAVLRLDAH----EELVVSVDSMlegVHFPFDSPPSELAYRAVAAATSDLAAMGARPLGMTLALTIPE-ADDAWLRELRLGLSDAVGDFSLPLVGGD---LTRGS---LTLSVQVMGAVPAGGAIRRDGARPGDRVCVSGPLGDAAAGLALIEGRVAgdgpANTALREHFWRPMPALDLGISLRGKATAAVDVSDGLLADLGHIAEASKVCVIVDSSQLPISEAVNSiASGEQALAWALGGGEDYCLGFTLPE----------SHELPPGSCVIGRVEEGAGVRCDAA-------------------
>UniRef50_C0ZXP1(45-282:343) Thiamine-monophosphate kinase n=11 Tax=Corynebacterineae RepID=C0ZXP1_RHOE4  E=2e-18 s/c=0.40 id=24% cov=57%
----------------------------------------------------------------------DIGRKAVAQNAADVVSMGARPTAFTVSLGCPPSTPVDVIDAISAGIWDAATDLGAGVVGGDLVQSPVVVVSVTVLGD--LGGRPAVLRSGA---KIGDKIAVAGLFGcsAAGLALLLDEAVLLDEAESFPDLLAAHrvpnpPYQSAWEAAESAHSMTD-VSDGLIADLRHLAEASHVRFDIVSAAVPTSPDVASAAEALDVDPL---------------------------------------------------------------------
>UniRef50_UPI0001C16452(23-327:349) Thiamine-monophosphate kinase n=2 Tax=Nostocaceae RepID=UPI0001C16452  E=2e-18 s/c=0.31 id=22% cov=69%
---------------------------------------------------------------------------AATANLSDLAAMGASPLGITVALGLPGDLAVNWVEQLYQGMSDCLQKYHTPIVGGD---IVRSPVTTIGI--TAFGEVSPDLIIRRCTAQVGNAIVITGMHGasRAGLELLLHPQtGENLKEEEKQALirfhQRPNPRLDVIYVLHEILISGLKPRGdsspvtlsgmdssdGLADAILQICRASQVGAVLHQDKIPLVPISNNwLTPLRWLDyALYGGEDFELVLCLPPTIAKALV-----LKLGSGAAIIGEITSGDQVILQ---------------------
>UniRef50_UPI00003C83B8(18-302:322) thiamine monophosphate kinase n=1 Tax=Ferroplasma acidarmanus fer1 RepID=UPI00003C83B8  E=3e-18 s/c=0.33 id=22% cov=60%
--------------------------------------------------------------------------------LSDIAAMAGIPSGFLISLSVSPEYDISYLEEFYRGVRHELDKFNVSIIGGDTK-----EGSDFTAAGTIIGKQVPELIRRRSEIKPGQFLMVTNSLGSSAAGyiyyMYGINRELGIRKML--DVEPrINEAIK--ISASGAKFMMDL-SDGVYASIHQISTDFGVGFKLYGDKIPFDRDVEKAASISNFSvsdiALSFGGDYELMFTVEKNSLEEFMAAM---------------------------------------------
>UniRef50_B7AVF9(38-297:305) Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus ATCC 43243 RepID=B7AVF9_9BACE  E=4e-18 s/c=0.36 id=22% cov=74%
------------------------------------------------------------------------GRYAVIDACNALACRGGEPEGINAAVTIPDSYDEKLLKKLIADIDAQCRTCGTHI--EDVAVSTSQHIRKPVITASAFGRSSEEMPAGMQKAGGNLDIIASGSIGMSGImnvldSHMDEAKKVYADSVINAAAADAGKLsvadrasLAAGAGASYLVAAGD---GGIYAALWRLAADNGCGFDINLRDIPVKQEIIEMCELFDINPYELSSTGCMLMTA--EDGCGIVDVL--NENGYDAVVIGHTTKEKAKMMHLEDEV-RYLDVPRNE------
>UniRef50_A9A3T2(1-293:310) Thiamine-monophosphate kinase n=1 Tax=Nitrosopumilus maritimus SCM1 RepID=A9A3T2_NITMS  E=5e-18 s/c=0.32 id=20% cov=85%
--------------MSKLDESEIIKIFQRKlGNKNSEDVEIFKLKQnIIAKTDTLVQSTD----IPPKMKLGEAARKSVVACVSDFAAKGVKPQYGIISINFPSNISRSKVEEAATGFRKACSEFGISILGGDT-----NAGKEIVFNVCLFGSAEKIVPRNGSESK--DLIFATGPFGYTGAglSILLykKKGKREFVAKAIKAVTHPKPRVDFGVKNKRYFTSSMDSSDGLSTTLNEMAKQSKKKFVINNS--PHKKDLGEFAksnqDNL---VFHGGEEYEFVFTINPKHKKTILKNAKS--LRTPIIEIGYVTTGKGVILQ---------------------
>UniRef50_A0RWJ0(23-306:400) Thiamine monophosphate kinase n=1 Tax=Cenarchaeum symbiosum RepID=A0RWJ0_CENSY  E=7e-18 s/c=0.33 id=27% cov=70%
---------------------------------------------------------------------------AVVSCTSDLAAKGVRPRYGLVSVTLPLDCTKNTVSGLAGGLAAAAKKFGFKFVGGDT-----GGGAELSISVFLAG--PADRIVPRGGARSGDMIYVTGPFGypSAGLQIIMggASSKKGFAArAIRAQLRP-EPRLE-----FGACAARLLTSCmdssdGLSSTLHEMARQSGTRYTLYR--LPAGAGIMGFASDNGLDgdslVLDGGEEFELVFTAHPRNRKRIEKT--ARKLGVPMQEIGRVEQGRGVWLASGDGMRRIKD-----------
>UniRef50_Q3ZZF3(26-324:336) Thiamine-monophosphate kinase n=5 Tax=Dehalococcoides RepID=Q3ZZF3_DEHSC  E=1e-17 s/c=0.31 id=22% cov=70%
---------------------------------------------------------------------------------SDIAAMGGLPQYAVVNIDLPPDTLVSSVTDCYNAMYSLANKYQTVIIAGDT---NQSSIINLAITLLGSAENPS-CLLTRNAAQAGQKIAVTGYLGNAAAGLDMLLNQTEVTDESRrifyRSFYRPKPRINEarLLVKEGVHCCID-ISDGLVTDLGHILRQSRVSARIELDKLPLHPSLRLSYPLQAQNmALYGGEDYELLFTASAKVIEQI--SVQSH---IPVTIIGEIIPGKPEELKLVDKDGRALQP----------
>UniRef50_A0NME7(10-304:332) Thiamine-monophosphate kinase n=2 Tax=Labrenzia RepID=A0NME7_9RHOB   E=1e-17 s/c=0.32 id=28% cov=50%
----------------ELIRRFFAPLAKDPGsLGLTDDAAVL----TPHQGYDLVLTKDVLAADIHFFaedaPEA-IAAKALRVNLSDLAAKGARPRGYLMGLSLPSDWTVDWLERFCNGLAADQAAYDFHLYGGDT--VRSGNGLQVSI--TAIGEVETGKAVRRSGAQPGDLLFVTGTIGD-AAAGLQARLNPDF------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B6IMS3(35-260:344) Thiamine-monophosphate kinase n=1 Tax=Rhodospirillum centenum SW RepID=B6IMS3_RHOCS  E=1e-17 s/c=0.41 id=27% cov=60%
--------------------------------------------VAVPAGMELVVTTDAMVAGVHFLPDDppeDIAAKLLRVNLSDLAAKGAVPLAYSLVTALPRDCAEDWLARFCAGLGGDQQRYGIHLLGGDS-VSTSGPVT---LTVSALGLVPAGRMVRRAGARPGDLVFVTGTVGDAALALLrvLGREPAALPQA--ADWAPLVARLRRPEPRLAFApALRDlasaglDVSDGLVADLGHIAAVSGVAIEIRADRLP--------------------------------------------------------------------------------------
>UniRef50_Q8D289(13-308:329) ThiL protein n=2 Tax=cellular organisms RepID=Q8D289_WIGBR   E=1e-17 s/c=0.32 id=21% cov=48%
---------------WNIIKNFFKKSKNinkNVAVGIGDDCAVLNIKKDSF----FVITTDTLVLNTHFLdsiKPKDLGYKSASVNLSDLASMGAVPKWILLSITIPK-FNKSWISSYSEGLFDNLNYFNVKLIGGD---LNKGP---LSITITACGTIPkKKIKMTRSGAKINDLIYITGTLGDsaAGLAILMK------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8NQV0(40-276:331) Thiamine monophosphate kinase n=5 Tax=Corynebacterium RepID=Q8NQV0_CORGL  E=1e-17 s/c=0.39 id=22% cov=53%
----------------------------------------------------------------------------------DIEAMGARPVAALLAISAPTHTPVEFVRGLARGMNQRLEEYSAELVGGDIT-----SGDSLVIAVTAIGQLGGSLPeLTLGRARPGQTLVAHGKIG-YSAAGLALLQHFGpdnvpehLRPLVDAHCAPvLTPGRGMVARAAGATAMTD-NSDGLIVDLNQMAMKSGVRIDVDSSSISPDELLSEAASVLGTDAW---------------------------------------------------------------------
>UniRef50_B3T8Q3(3-309:318) Putative AIR synthase related protein, N-terminal domain protein n=1 Tax=uncultured marine crenarchaeote HF4000_APKG6B14 RepID=B3T8Q3_9ARCH  E=1e-17 s/c=0.30 id=18% cov=88%
------------KLSEKKIIELFQNRLGNTNFVPE------DVESFKIGKKRLVAKVDTLVEStdvPPGMKLEDVARKSIVSCVSDFAAKGVKPIFGIVSLTIPKRLSRSNIESLAKGFQRAAGEFKLKILGGDT-----NEGKELVINFSLFGISEKIVN--RKGAKTNHVIITSGPFGysGAGLSILLKNKNgskKFKAKAKSAVFRPNCRLTFGLKNKNYFSSSMD-SSDGLSTTLNEMSTQSKKKFVI--TRMPSENDVFDFASSNGLNAndliFNGGEEYEIVATANTSNLTRIKKYAKKHR--IKLYEIGYVTKGSGVFYKKDGKLIRIKD-----------
>UniRef50_C0GCU5(9-324:335) Thiamine-monophosphate kinase n=1 Tax=Dethiobacter alkaliphilus AHT 1 RepID=C0GCU5_9FIRM  E=2e-17 s/c=0.29 id=26% cov=89%
---------------RALIKQ-ITEVLGESASANGFVGIGDDAALTTCNKEAWLVTSkDMLVEGVHFlLPAmtpADLGYKALAVNISDIAAMGGVPRHAYVALALPKETGVEFILEFYRGMGPLAAELGTTISGGDT-VSSPGP---LMISITVQGEVDRQKALLRSGASPGDILCTTGPLGASAAGLALLLNrELDCPEKLRSQALNAHfrpvPRVREadfLAHSGAVTAAMD-ISDGLLEDLGEISQASGCGVLLEEDKIPVHPAAQQIAPLaqsLAAEwALNGGEDYELLLAVQSRRFAS-LSREYESRFGVPLMPIGKVVGEKGLWMVTKEG-----------------
>UniRef50_A7B5B2(60-332:345) Putative uncharacterized protein n=2 Tax=Clostridiales RepID=A7B5B2_RUMGN  E=3e-17 s/c=0.34 id=22% cov=76%
----------------------------------------------------------------------NIGVYAIMRAVLDLETRGASAIGVSVQVILPTYAYESRLKEMFRCMEERCASWGIAITCA--KAETSPAVSQSVVSVTAAGSVEKGQLRTLAQAEPNQEIVLCGSIAAEGVLriFDEKREELskrfvpafmrqiqGIESELE--VFHALRSVKQENTPKGeplVTAMQQIGSGGILASLWELTEAANVGMQIEMSRISIRQECVEVCEYYHLNPYQMTSAGTVLMVTRDGNA--LVRCL--EESGARASVLGVTTADHAKVI-TSGDEVRYLDRPAPDELMR--
>UniRef50_C0R0M8(54-355:358) PRK00943: selenophosphate synthetase n=2 Tax=Brachyspira RepID=C0R0M8_BRAHW  E=3e-17 s/c=0.31 id=26% cov=71%
----------------------------------------------ISDDNALIFTVDYFppvIADPYGF-----GQIAACNSISDIYAMGGEPK-LALNITM---FPKDDSLNILANMlkggQDKATEAGVLVVGGHTitdASVKYGM--------AVIGFANPNKITTNAAAKEGDIIIFTKPLG-TGACLAAMRQGLIKESHIEDVFESMKTLNKkacAVMNKYNVKCATDITGFGLIGHAYKMAKASDVTIEIQSSALPmfnktyevldmgcipgaaftnmryvgdnikVDDNVDYNLKMLSFDPQTS---GGLFICADKSNAENILADLWREGIDC-ACIIGKV------------------------------
>UniRef50_B9KXI5(12-331:341) Thiamine-monophosphate kinase n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9KXI5_THERP  E=3e-17 s/c=0.29 id=23% cov=92%
----------GEEELIEQIARLVGDRSNRVSIGIGDDAA----AWRPRAGHELVITTDTLIERVHFRLEWTdweaLGHKSLAVNLSDIAAMGAIPRLAVVDLAVRGTERDRDIADFYRGVQALARRFGVAIVGGDTTRSPLGVA--VSITVIGESPRDGHRLLRRDAGRPGDLIGVTGPIGLAAAGLRVLERGLKtLDGNpVMQEHYHrPQPRVREglLLRRCGVRAAMD-ISDGLLGDLQKLCRASGVAAIVDLERVPVPNAIKWAFPDWEEVALRGGDDYELLFAAPPAVFARVARAFARAGL-LPPWKIGQLVEagsaGPIVELRDVTGRCRPAD-----------
>UniRef50_Q0APG5(39-308:320) Thiamine-monophosphate kinase n=1 Tax=Maricaulis maris MCS10 RepID=Q0APG5_MARMM  E=4e-17 s/c=0.34 id=25% cov=68%
--------------------------------------------------------------------------------LSDLAAMGARPRGYLSAIAWPEALDAAWREAFVRALHREQSRYGLVLIGGDTTSTP----GPLTVTLTLVGQIETGTALRRSGARPGEDVWVSGMIGDGLLGLLSARKaGTELAGALERYQAP-DPRLELGLALRGLASAAIDVSDGLLADAGHIAAASACSLRVDVDTVPVSPTARDWLESGGaLDALLAGGDDYELLFTAPAGCRERIAAL-GLSLDTNLTRIGSVMAGEGV------------------------
>UniRef50_B8KWB4(7-304:312) Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium NOR51-B RepID=B8KWB4_9GAMM  E=6e-17 s/c=0.31 id=27% cov=84%
----------------ELIGRYFASLGGGDRiaLGIGDDAAVFD----VPEGEQCVVSTDTQVEYVHFFPETlpeDIAYRAVAAAASDLAAMGASPLGMTLALTLPEADEL-WLHGFSQGLAAAVRDLALPLMGGDTTQGP------LTITITVHGSVPRDAAVTRGGARPGDRLCVTGTLGDAAAALALQRGELSGDrlpeaEDVEWLLSRFNRPIARFEWLSFLRAhgsAAIDISDGLLADAEHIAAASGVALTIDSTAIPLSDALRRAApsEARLFEwALGGGDDYELLCTVPAG---------CQIPDGL--AVIGEVVVGQGVQIDRPTSG----------------
>UniRef50_C1F3W9(20-288:338) Thiamine-phosphate kinase n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F3W9_ACIC5  E=6e-17 s/c=0.34 id=22% cov=50%
--------------------------------------------------------------------------------LSDLAAMGASPLAAFLSLAAPPErmrpqgrAKKSWLDRFLDGLLALADAHGVSLAGGDTAQSPMG---GVIADIVLLGQTPRGRALLRSGARAGDRLYVTGALGGAAAELLALGHGQSLR--LKGATAHPQLFPQPRLAVGQrllgarLATAAIDISDGLSTDLDHLCEESGLAAVIDAAALPVHP-----------------------------------------------------------------------------------
>UniRef50_Q3A8K1(30-320:329) Thiamine-monophosphate kinase n=2 Tax=Desulfuromonadales RepID=Q3A8K1_PELCD  E=8e-17 s/c=0.31 id=28% cov=72%
------------------------------------------------------------------------GRKSVSVNVSDIAAMGGRPRHLYLGLGVPADFSVEELQLFMDGFLEAVTAYGACLVGGDTCRSP----GPLLISVTAEGSVAAGREVRRAGAGIGQIIYVSGTLGDSALALQQLGKGEVPDSFLASrhhDPTARVALGQALAQAGLATAMID-ISDGVLADLGHILKASSVGALLEESLLPLSGAFRAVLQhaphLLQL-ALSGGEDYELLFTVAPEREAEV-DAL-ARTLALPLTRIGVITSaDEGLRLRAADGSLR--------------
>UniRef50_B7A847(31-310:313) Thiamine-phosphate kinase n=1 Tax=Thermus aquaticus Y51MC23 RepID=B7A847_THEAQ  E=8e-17 s/c=0.32 id=27% cov=69%
----------------------------------------------------------------------------VAATASDLLVKMGRPLGFTLGLFLPPELEEAFALGLVQGAAEAAGRLGAPLLGGDT-----NAGEEVALTVSGFALSHAPL---PRRARPGDLLFLAGDrWGRVGAAILAHYRGRSLEGFPEIRQAAFYPLPRLELLALSGLL-----RGGLdsSDGLAEtLWQLSELGVRVDLEALPLYPDVLAFAggedEALEL-VLYGGEEFEAVLVVPPEAEGAVLA--RAEAVGLPLFRAGRVGEGEGVYLRGRPVLRR--------------
>UniRef50_Q8TVM0(14-325:334) Selenide, water dikinase n=1 Tax=Methanopyrus kandleri RepID=SELD_METKA  E=9e-17 s/c=0.29 id=27% cov=88%
-------HGUACKLPQGDLEDLLKGVELPEEGGRVEVGVGDDAAVIRVDGGYVIQSVDFFTpIHPDPYTQGRI---AANNSINDVFAMGAT-EVLSVLVVsgFPRELPEEDAREMLQGFADQCREVDALIVGGHTIMNPWPILGGCV---TGF----AERYVTVGGAEPGDVLYLTKPLGTQPAMAALrlpedVRKQFLTDSELEEavDLAvevmtePLKDAAEAALEV-GVHAMTDVTGFGLKGHAGEMAEASGVRVVIER--LPVIPGTTELSRALgyGLERGESAeTAGGLLVAVPEEHAEDLEDAFERRDVWY--RRIGRVEEGSGVEVRG--------------------
>UniRef50_A0B852(43-304:325) Thiamine-monophosphate kinase n=1 Tax=Methanosaeta thermophila PT RepID=A0B852_METTP  E=9e-17 s/c=0.34 id=25% cov=63%
-----------------------------------------DCAVVELDGDYLVVTTDMLH-RETDFPDqatpWQIGWMSAAVNLSDIAAMGAEPLGVLIASGIPPETDLEFVEEIFEGIRDCVKAHGTEVLGGDT-----DAHRELTICGTALGRVSRERILRRRGARPGDLLCTTGSLGGAGAGLKALKiGRIDLARRLLEPCPRVREGI-ALAGTGAVTAMMD-NSDGLALSLHDLAEAGGTGFLVECERIPIAEEVRAIAE----------------------------------------------------------------------------
>UniRef50_C8WEQ3(5-303:321) Thiamine-monophosphate kinase n=5 Tax=Sphingomonadaceae RepID=C8WEQ3_ZYMMN  E=1e-16 s/c=0.30 id=22% cov=62%
-----------------------------------------DAAVLPRPSGDLVLSHDIIVENVHYFPSDPPETVAqklVGVNLSDLAAKGAKPIGALMGYSL--GPDYKWDQAFLKGLESVCHQYNLPLLGGDTVAVPRHTGH--FSAMTVIGLAPSCGVPDRRAAKEGDELWVTSPIGDAGFGLNLLKQKKNINHSAQEKLvqayrSPEPRLKEGIWLAPHVHAMAD-ISDGLLIDAERIANASGLAVRIRLDRVPLSSE----------------------------------------------------------------------------------
>UniRef50_Q10XH5(10-325:341) Thiamine-monophosphate kinase n=6 Tax=Cyanobacteria RepID=Q10XH5_TRIEI  E=1e-16 s/c=0.28 id=22% cov=84%
---------------QELLKKL--RHFCPENII-GDDAAILP----TQPNKSLVVTTDTLVDGVHFsdrttSPE-DVGWRSAAANLSDIAAMGAFPIGITIALGLTVDTPIAWCEQLYQGISECLQPYNTPIVGGD---IVRSPVSTISI--TAFGQIDGGYTILRSNCQPKNVIVATGVHGasRAGLELLLYPELGESLTELErSDLilahqrpKPRLDILDTLWDCLSLNSFS-ATKGsknsilvggmdssdGLADAIIQICQASQIGARIERNQIPIpHSLTKFVSDEQALNwALYGGEDFELVLCLPPNCGQELVKRI-----GVGAAIVGTTTNNTDILL----------------------
>UniRef50_C1ZKV1(4-312:320) Thiamine-monophosphate kinase n=1 Tax=Planctomyces limnophilus DSM 3776 RepID=C1ZKV1_PLALI  E=1e-16 s/c=0.29 id=23% cov=86%
---------TGGRMTFRpefaLIERIRKAAGGSsrVLLGIGDDAAGL----GSREDRETLVATDMLLDGVHFVveecgPYW-AGRKALAVNLSDLAAMGGRCIASFVSIAIPRNWNAHEADELMRGVLELAAKWDCPVAGGDT-----NSWDGrLVINVAVVGETIEATSIRRAGAQVGDVIVVSGAL---GGSIYG--RHLKFEPRL--DVAA------ELLKLAKLNSMIDL-SDGLSSDLWHILRASHAGAVLEQKRIPVHEDVRHHADVVNLSsppalahALHDGEDFELLFTLSPAQ----WETLRQNWKLPIAlTKIGTIVSEEACRIVSETGE-------SKELVP---
>UniRef50_A5WHT2(5-305:372) Thiamine-monophosphate kinase n=4 Tax=Gammaproteobacteria RepID=A5WHT2_PSYWF  E=2e-16 s/c=0.29 id=24% cov=65%
----------------ELISRYFTAASSEQALSQsvacttiakgvGDDAAVVALSSPT----QWVTCVDTLVQGRHFAEDWDqvetlafaIGYKSVAVNVSDIAAMGAKPHSILLALALPQQLAKEaWLSDFAKGLFHACSQFGVQLIGGDTTRSEK-----LVISVTANGFIDKALtPIYRSGAQVGDKVYVSGTLGDACYALYhpdtqvgkQLSHRLNMPTPRIS-------LGNTLAAEGDVTAMID-VSDGLVQDLSHICEQSDVAVRLHLDKLP--------------------------------------------------------------------------------------
>UniRef50_B1Z181(16-351:354) Selenide, water dikinase n=141 Tax=Bacteria RepID=SELD_BURA4   E=3e-16 s/c=0.26 id=26% cov=87%
----SLSHGGGcgckiapGVLS-ELLKRATPPALFPDLLvgtETSDDAAVYRLN----DEQAIVATTDFFmpIVDDPF----DFGRIAATNALSDVYAMGGKPI-LALALV---GMPInvlphETIAAILRGGESVCAEAGIPVAGGH----SIDSVEPIY-GLAAIGVVHPSRVKRNAAARAGDVLVLGKPLGVGVLSAALKKNQLDAAGyaQMVATTTKLNRPGAELAALPGVHALTDVTGFGLLGHTLELARGANLTARVHYASLPWLAGVEAFVAdgvftgasgrnwaaygtdvrlADGLPPVAQAlltdpqTSGGLLVACAPEAVDDVLACFRADGFDR-AAVIGEMVDGPSRV-----------------------
>UniRef50_Q2NE22(9-313:333) ThiL n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NE22_METST   E=3e-16 s/c=0.29 id=20% cov=67%
---------------RKLIQRLLKKRdetlgnIDNTILKSYHDDAAIEENT----SKYTVLSTDMLIQHSHFPKQMTyfqMGEKIVTVNVSDILAMNATPVSILIAMALPSTLTIDEFDEIIDGILYKCKEYGVTLIGGD-----LNQSDEIILSATTTGKINKNIKLQ-SNIQEDNLVAITGQLGMPAAAldLLSKYEIKDLSNEyeeiIKSILEPNLPIKTAkfLREHPTlITSMTDIT-DGLAIELGHLHEKnTNIGFEIYADKLP--------------------------------------------------------------------------------------
>UniRef50_D1CEL5(44-352:354) Selenide, water dikinase n=2 Tax=Bacteria RepID=D1CEL5_THET1   E=4e-16 s/c=0.29 id=26% cov=74%
------------------------------------------------EGQALVQTVDFFppiVDDPYTF-----GAIAAANSLSDIYAMGGTPI---LALNIagwPGNLPLDMLAQIFRGGMDKVEEAGAVIGGGHT-VMDQEPKYGLCVT----GLIHPGKITTKGAVKPGDLLVLTKPLG-TGVITTALKSGKVRDVDIQAAVDSmlrLNKVASELAVELGIRAMTDITGYGLLGHAFEMSEASNVCLNIELSKLPVLPGaldyirqdiypgglnrnrsyltgeqdgrkkisydnsiiVDENLVKLAMDPQTS---GGLLIAVPQEQADEFTA--RAEQRGQSIWIIGFASEGYGVRL----------------------
>UniRef50_A8ABX6(50-347:713) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Thermoprotei RepID=PURL_IGNH4  E=5e-16 s/c=0.29 id=24% cov=83%
---------------------------DSPWVVKGGDAAVVDFGSV-----YVAFRIESHnhpsAVDP--YNGAATG---VGGIIRDILSSGAKPIALLDDLIfgdLDENLVKWHVKGVVKGISDYGNRVGVPTVGGETWFDPDFTRN-PMVSVACVGVCPKDKLIN-GTPRPGDLIVIagnyTGKDGLLGSSFASKNLEEGVEEEYAAIQVPdplmeklLIDSILEMRDERLLVFVKDLGGGGLATALSEVAASFGLGVEARLDALHLREP---------MEAWEIVvseSQERMMLVIRPEDLERAKKVL--EKYDVPYSVIGKFTDTGRVVL--YYNGEKVADLPAK-------
>UniRef50_B2RLG7(58-338:348) Selenide, water dikinase n=4 Tax=Bacteria RepID=SELD_PORG3   E=6e-16 s/c=0.31 id=27% cov=72%
----------------------------------------------------LIVTTDFFppvCSDPYTF-----GRIAAANALSDVYAMGGRPlLVLNLTMFPSEGIPVEVLADILRGGQQTIDESGAFTMGGHT-------IDDPIpkYGLAVTGIVHPEHLVTNAGVRAGQCLVLTKPLGI-GVAMAAHRLGLigseVYEAAIGQMCL-LNRAGAELMQKYGIRGATDITGFGLLGHAKELAEASDVCLHIDSRSVPVLPEclsllrdgcipgatfrnLRFVGDMLRADcpteyKMLLADAqtsGGLLMAVDADRAEDLVADLHRTGLHPFAAIIGYATD----------------------------
>UniRef50_C0GR51(10-312:315) Thiamine-monophosphate kinase n=1 Tax=Desulfonatronospira thiodismutans ASO3-1 RepID=C0GR51_9DELT  E=7e-16 s/c=0.29 id=28% cov=83%
----------------EIVNSLFPREHPHMVVGRGDDCAVLKCPA------SLCMSSDLFLEDVHFrtryFTPEDIGHKALAVNLSDLAAGGARPLGFNLNLIWPVYLDEEFCRSMLSSMAELGAKFKLALTGGD---LSFGKSLGLAV---CIWGKSPARQMLRGKAEPGDVLFVVGKAGLAACGLSLLEEndpGLDRYPECVAQHLRPRPLVREgqvLAGIEEVKGLMD-VSDGLARDLPRFCRR-GTGVEICSD-FRVHPEVAFFCRDRGLDPLATALKGgedyALLGACTRKGWDTV------KKKILDCRRLGTVTDKPGIFLQ---------------------
>UniRef50_B4D453(27-306:306) Thiamine-monophosphate kinase n=1 Tax=Chthoniobacter flavus Ellin428 RepID=B4D453_9BACT  E=8e-16 s/c=0.31 id=25% cov=63%
---------------------------------------------------------------------------ALCRAISDIAAMGGIPAHALITLAAPAATPVDRVKALYAGLRKAARKYDVGIVGGETSRSP----GPLFLNIALTGWVERQQCVLRSGGRPGDSLYVTGRLGG-----SLAGKHLDFQPRIE--------EARWLVSHFKPRAMMDL-SDGLAADLPRLAAASQCGYTIDEACLPLNT---------GCTPTQAMSDGedfELLFALPARSATALEAAWKKRFPRLPLTQIGRLIPHSAIR-----------------------
>UniRef50_B5EQ44(2-300:340) Thiamine-monophosphate kinase n=3 Tax=Acidithiobacillus RepID=B5EQ44_ACIF5  E=9e-16 s/c=0.29 id=27% cov=69%
---------AGGEF--AFIEQLrcrLGKMASDVRLGIGDDAAWLD-----PAGRQLVATMDTLVAGRHFFPEVSPEDLAWkalAVNLSDLAAMGAEARWCLLSLALPwraEGYG-EWLEAFATGWSALADRHDVTLVGGDT-VATDGP---LTLSITALGLSGHGV-MRREAARPGDVIWVTGTLGDAAAALDLALVERGQERRAVPCSAPRRDALEarrlrptprlefgAAALAGGVLCAVDCSDGFLA-DLGHILKASGVHAQVALDALPLSPD----------------------------------------------------------------------------------
>UniRef50_D0LRS0(75-366:381) Selenide, water dikinase n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LRS0_HALO1  E=1e-15 s/c=0.30 id=26% cov=78%
----------------------------------GDDAAVVRLPGDAASGRALVLTTD--VIAPLVDDAESFGAIAATNAVSDVYAMGGRPLYaLNLAFFPDQSLPLEVLRAILRGGARACERMGVAIVGGHT-VRDSALKYGLAVT----GEVDSERAWRHEGGRAGQELVLTKALgtGVLGTAIKRGEASAADSAAAIASMSTANRAAAEIGQRFAVSACTDVTGFGLLGHLRNIVRASAVDAELELDALPLLPGaleharagrvpggskanLAFLAPMLAgadeVDPALLAlaadaqTSGGLLLCVAPEHSAAMLEALRA--SGLPAARVGR-------------------------------
>UniRef50_D1U5K6(9-313:317) Thiamine-monophosphate kinase n=1 Tax=Desulfovibrio aespoeensis Aspo-2 RepID=D1U5K6_9DELT  E=2e-15 s/c=0.28 id=24% cov=83%
----------------DLIGAHFPTGHEFLRLGRGDDCAVL------AGGSDICVSSDLFLEDVHFrrgyFTAEDIGYKALAVNISDIAAMGARPFAFTMDLMIPPDLDEDFWNGFFKGMSALARHNDLALAGGD---LSRADRLGVSISIFGVGGS-KGRFLTRGNCAPGDILFTVGDLGlaRAGLMTLEALGEKGREAFPTAVLAHLRPkpkvLIGTLLNAAGIKGLMD-VSDGLARDLPRF-LGPKVGADL---TIPtnvLNGNVIAFALATGADPVELAmlggEDYALLGVMDEETREKAASV-------PGFTELGRVTDTPGILVNGK-------------------
>UniRef50_D1CF57(13-319:334) Thiamine-monophosphate kinase n=1 Tax=Thermobaculum terrenum ATCC BAA-798 RepID=D1CF57_THET1  E=3e-15 s/c=0.28 id=23% cov=87%
---------------KRLVDKL-PEYGRDVIVGPGDDVAVL----RTSSDKYLLATIDSQVEGIHFlfeYTGARqLGEKAIAINVSDIASMGGQPRHALVSLALPDSCQLKLVEELYEGIYSASHAYGLDVIGGNI----SSSRSGLLVDVCLLGEVEPEHLVLRSGAAPGDGIYVTGWLGSSAAGFELLCSKLrncdeRIWEELTSSHLTPKARLyeaRSLVATGAVSAMID-ISDGLISDLGHILEASGVGAVVYTDRLPIATAVREVASTLGKDalrwALSGGEDYELLLTGDRRVLDGIASD--NGLGGTPLTLIGEILPQSaGLQLEGL-------------------
>UniRef50_B2SNW6(63-350:365) Thiamine-monophosphate kinase n=21 Tax=Gammaproteobacteria RepID=B2SNW6_XANOP  E=3e-15 s/c=0.30 id=21% cov=68%
--------------------------------------------------------------------------------LSDLAAMGAQPRWCTLSLSLPHD-DAAWVDLFADGFFALADAHDIVLVGGDTTRGP------LSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGEaaaalalwqAGQLDVTCAAADPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISDGLLADLGHLCDRSGVGaqlALAALPAMPRSAGTSVAqCP--GWQ-LGGGDDYELCFTAAPQHRAAVAQAMEFAEVA--ATRIGQIVATPGVVVHDADG-----------------
>UniRef50_A8I0K0(37-352:358) Thiamine-monophosphate kinase n=28 Tax=Alphaproteobacteria RepID=A8I0K0_AZOC5  E=3e-15 s/c=0.27 id=26% cov=89%
----------------DIIARYFRPIATHAEARGLFDDAAL---LTPPPGCDLVLTKDALVAGVHFFaddPPASIARKALRVNLSDLAAKGARPLGALLAIALPRPMDPEWLGAFAEALGADAERFGCPILGGDT-VSTPGPVT---LSITAFGAVPTGGFVPRTGAAPGHALLVSGTIGDAalGLQLRLAPDRPGFEAlsaeqkAFLADrflhPQPRLPLAEALRDHAA-AAM--DVSDGLVGDFAKMMSASGCGGLVRAAQVPLSDaaaAAIAAEPALLADVLGGGDDYEIATAVPHDAVPVF--RAAAQAAGIAVTVIGETYKGDGLDLVGLDGQPLYLDR----------
>UniRef50_Q9UY56(12-309:334) Phosphoribosylformylglycinamidine cyclo-ligase n=4 Tax=Thermococcaceae RepID=PUR5_PYRAB  E=3e-15 s/c=0.29 id=24% cov=80%
------------EKTARALREIIRTARETFKLRKGKVGEPGDIGHYAAlldfGNFYLAMTTDGVGTKVLVAEAVGkfdtIGIDMIAMNVNDLLCVGAEPLALVDYFAVKEP-NEEVFKQVAKGLYKGAEEAGVAIVGGETAVMP-DLINGYDLAGTAIGIVEKGKVITGERIRPGDSVIGISSSGIHSNGLTLARKllipKYGLDYEYEG--RKLWEwlleptriyvrPILELINSVEVHGLAHITGGGL---LN-LKRLTNYGFELE------MPPIEGIFKLIhenGV-PLDemfrVFNMGVgFIVVVPQEEKEEALEILSRH------------------------------------------
>UniRef50_Q214H1(21-314:338) Thiamine-monophosphate kinase n=2 Tax=Rhizobiales RepID=Q214H1_RHOPB  E=5e-15 s/c=0.29 id=25% cov=69%
-----------------LIARYFKPLANHAGAFGLSD----DCAILTSSGDDLVLTTDAIVEGVHFLPDDppeSIARKALRVNLSDLAAKGASPAGFLLTLAL-RSAEESWLAPFAKALGEDAAAFGCPLLGGDT-VSTPGP---LMISVTAFGRVPAGRMVRRAGARPGDHVVVSGTIGDAALGLDILKGGPAAGAvSGEARAALVQRYREPQPRSALAQAVRDhasaamDVSDGLAGDLAKLCAVSAVSAAIDAAAVPLSEAARA-------------------------------------------------------------------------------
>UniRef50_B1H0F2(16-287:331) Thiamine-monophosphate kinase n=1 Tax=uncultured Termite group 1 bacterium phylotype Rs-D17 RepID=B1H0F2_UNCTG  E=6e-15 s/c=0.31 id=22% cov=68%
----------------DMIKNQFADSKDNKNIVA---GIGDDSFCFKSGKNNICITKDMLVEDVHFKKDWtnpqEIGRKSIEVNVSDIAAMGnVKPEYAFIGLGLPPKTSEIFIKNLYKGFKKACDKYKMAIAGGNTV-----RADKTIISVTIVGIgIGRERVIKRNGAGIGDLIGVTNTFGDAGAGVALLykygtkhkynkYEHFLISKQNNPKAR----LKEAQKISKHLTSLTDA-SDGLYISVDLLAKDSGKGAEIYMDKIPVSSSLK--------------------------------------------------------------------------------
>UniRef50_A3CSR3(21-280:288) Thiamine-monophosphate kinase n=4 Tax=Methanomicrobiales RepID=A3CSR3_METMJ  E=8e-15 s/c=0.32 id=27% cov=66%
------------------------------------------------------------------FPAGmtdwQIGWMATAVTLSDVASMGAAPGEVLLAV----GLDRpERLSGIMEGARDCCTRFGAELVGGD-----LDAHRELTIVSTGLGLVAPEHLVRRRGARPGDVIAVTGPLGEAEAALAGYDRH-------RRELLEPQPRVREgqALGRAGVSAMMD-ISDGLVLSLHDLLAVNDCGFSVDTARLPLPAGVP---EDEGRElALYGGGDFELLFTAPPDILP---------VPGVEARVIGEVIPERTVLADGE-------------------
>UniRef50_A5CQP0(32-273:361) Thiamin-monophosphate kinase n=4 Tax=Actinobacteria (class) RepID=A5CQP0_CLAM3  E=9e-15 s/c=0.35 id=27% cov=59%
-----------------------------------------DCAVVRAPDGRFVITTDMMIEGPDFRLAWssthDLGRRAATSNLADVAAMGARPTALLVAIAAPAATRVADLEALADGLREGCllQAPGCGVVGGDLSV-----ADALVITVTATGDLEGRDPVLRSGARPGDVIAVAGTLGMAAAGVRLLFDHArsaeaddvpvpdaalaralraSHPTAVEAQLAPVAPLTAGVEAARaGATAMLD-VSDGLLLDLGRMARASGVGIDL--------------------------------------------------------------------------------------------
>UniRef50_Q0VMI1(26-317:325) Thiamine-phosphate kinase n=1 Tax=Alcanivorax borkumensis SK2 RepID=Q0VMI1_ALCBS  E=1e-14 s/c=0.29 id=24% cov=69%
----------------SLIRRYFHHRQgDSVVLGPGDDAAIL----APPVGQQLVMTQDTSLADRHFpsdMAPEDVGYRCLAVNISDLAAMGAMPLWFLLSLTLPR-VDEDWLAGFSNGLFELADQAGISLVGGD---ITRGP---LAISIQATGAVPPGQALRREGACAGDRICVGGVTGGGLLGLEQWQAGQRYGPAIEH-FRRPRPQWELGMALRGQASACIDISDGVLADLNHILQASGaLGACIDEASLPEDPCVLAGC-----------------------------------------------------------------------------
>UniRef50_Q1DAT6(47-345:352) Selenide, water dikinase n=6 Tax=Bacteria RepID=SELD_MYXXD   E=1e-14 s/c=0.28 id=25% cov=68%
-----------------------------------------------------------------------FGAIAAANALSDIYAMGARPLFALNLVCFPDELPLKVLSKILAGGQSKADEAGIPILGGHSIRDPEPKF-----GMAVTGVVHPKKVLTNAGAKPGDVLFLTKPLGS-GIATTAIKRGVASKQLAKRALGVMTTLNRAAGEVfasgkFKVNALTDVTGYGLLGHLLEMMTAAKARATLDLERIPLIAEVPALAED-GVVPggtksnlahvhkkvrfpeglpeciqWVLADAqtnGGLLASVPARQALKALKALEAA--GVDAALIGEV------------------------------
>UniRef50_Q182I1(44-345:348) Selenide, water dikinase n=18 Tax=Bacteria RepID=SELD_CLOD6   E=1e-14 s/c=0.27 id=23% cov=78%
------------------------------GLDTADDAAVYKLNDDMALIQTLDFFT-PMVDDPYVF-----GQIAASNSLSDVYAMGGKPLVAMNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHT-VDDKEPKYGLSVS----GIVSPNKVLSNATAKPGDKLIITKPIGV-GVLNTAMKEGMveqHIADKVIEIMIHLNKYAAMSFEKFDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGaiemaqmgiipagmyknmhyVSKDVEVVGnievavqdilYDPQTS---GGLLISVKEELAEELVKDMKLNG-AIEAKIIGSVV-----------------------------
>UniRef50_C9RGW7(21-323:333) Thiamine-monophosphate kinase n=1 Tax=Methanocaldococcus vulcanius M7 RepID=C9RGW7_METVM  E=2e-14 s/c=0.27 id=22% cov=83%
-----------------LIKKTLTYSNQNIIKGIDDDCAVIK----IDENRYLVATTDMMVKNthiPSILTPHEIGGRILTANVSDIASMGAKPLAFLLSISLSKKEAKEDFiKELYKGLDEFSRLYDCPVVGGDT-----NKGDELVLSGTAIGITDNPIFREG---RVGDKIGITNDIGRVYCALklyyLLKNRKIEVKefkklcskyPLIINKLKVPIARVKEGILLNKYRLLRGCcdISDGLG---KEI--TYFKNFELNSDHIlkAVPEDVFEFCEEFSLDPLTVAlnsgEEFELLFTTS--NINKVKRVLKHH---SKVFEIGKVIEE-GRYIDGEM------------------
>UniRef50_C8S195(415-730:730) Pyridine nucleotide-disulfide oxidoreductase family protein n=1 Tax=Rhodobacter sp. SW2 RepID=C8S195_9RHOB  E=2e-14 s/c=0.26 id=28% cov=59%
----------------------------------------------------------------------------------------------------------ETLREIMAAASEVFRAEGADVVGGHTAT---GAELTLGFTVTGL----AKRILAKGGARPGDALILTKPLG-TGTILAAEMAGQRAPGLMLGEavVAALASMTRSLGPDAAIltpqaHAMTDVTGFGLAGHLLEMLTASNCAAEISLPAIPLLPGAealaatgaasslapanRAACtarmafndtprAALLFDPQT---AGGLLAAVPADQATALLTALHAA--NVRAAIIGQATEGaPFLTIKT--------------------
>UniRef50_O28339(140-387:765) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Euryarchaeota RepID=PURL_ARCFU  E=2e-14 s/c=0.33 id=23% cov=65%
----------------------------------------------------------------------------------DVLCMGAQPIALIDPLFfgnldtpyekLPRGTkhPLYLLKGVVAGIRDYGNRVGIPTVAG-MVFFDNSYLTNCLVNVGCVGIVRKDRIIHSRAGGAGDLFVLaggkTGRDGIHGVTFASAELDEKSEEEARGAVQlgnpimkePLIHACLEVVEKGLLTGMKDLGGGGLSCVIGEMALAAGFGAEVYLDKVPLKEE--------GMAPWEIwISESqeRMMLTVRPEHIDEVLYIFQK--WDVPATVVGKVIPEK--------------------------
>UniRef50_Q1ASC8(25-278:314) Thiamine-monophosphate kinase n=1 Tax=Rubrobacter xylanophilus DSM 9941 RepID=Q1ASC8_RUBXD  E=2e-14 s/c=0.32 id=29% cov=58%
----------------------------------------------------------------------DVGYKAVAVNVSDVAAMGGVPRFVLCSGGAPEA---EAVLRCFRGVAEACAAFGAYPLGGDTTRAGALTVD-----VAILGEVPGGRPVLRSGAVPGDLLAVTGELGAAAAGLLALRRGEGGFGRLVGRHLRPEPRVREGLEaaLLGAHAMIDL-SDGLATDAGHLCERSGVGCRIDLRRLPVSGEVRRLAEAAGEDAEVLAATG---------------------------------------------------------------
>UniRef50_Q73JP8(20-352:354) Selenide, water dikinase n=3 Tax=Bacteria RepID=SELD_TREDE   E=4e-14 s/c=0.24 id=23% cov=84%
--------GUGAKLSAGALDKLLknFSVRNDDNLLVGFNTSDDAAVYKINDKTALISTID-------FFPpvSGDpyiFGQVAAANSLSDIYAMGGEPkLALNL-FCITKDMPEDMIKEILRGGFDKVYEAGAIVCGGHT-IYDDSPKYGLAVN----GFVHPKKILENSTAKEGDVLILTKPIG-TGILLtaskadMSPPEELDRCYKIM---AFLNAKARNIMVKYKINACTDITGFGLLGHLYEMGKGSGMSIEVDYKSVPIYKSVIESAEMgmmpagvysnrnfvgdnivfenvplayqdLMFDPQTS---GGLLISVDKEDAaalyEELSQALENTPCGKPA-IIGLVTKR---------------------------
>UniRef50_D1VW68(69-342:375) Thiamine-phosphate kinase n=2 Tax=Prevotella RepID=D1VW68_9BACT   E=4e-14 s/c=0.30 id=21% cov=50%
--------------------------------------------------------------------------------ISDVFAMNGTPRQMLVSLAIDKRFSVEDIEAFYNGLRMACNKWKVDIVGGDTTSSRTG----VAISITCIGEAKSEEIVYRNGAKDTDLICVSGDLGAAYMGLMLLEreksvyykqvdeirtkilkakeqknqalvtkltHDLNSLGNFQPDFAGKEYLLQRQLQTEArgdiietLRAAHIhPTamidiSDGLSSELLHICKESNCGCRIYEKNLPI-------------------------------------------------------------------------------------
>UniRef50_Q7UPP0(67-288:316) Thiamine-monophosphate kinase n=1 Tax=Rhodopirellula baltica RepID=Q7UPP0_RHOBA  E=6e-14 s/c=0.36 id=27% cov=65%
----------------------------------------------------------------------DIGFKAMAINLSDIAAMGATPSSALVTLALPAENATEIAGEVYEGILEAAQKYQVAIAGGDLSTYD----GPLSISITILGWTEQP--WLRTGAEEGDALFVTGALGG-----SLLGRHLRPEPRVE--------LAAKLKQTVNVHAAID-VSDGFSLDLDRMLAASRMGAELELETLPISEAAHQFAEKSGRTPLEHAwSDGedfELIFCVAPEEA----AIIESTDWGVPVTRVGKVVGRTGL------------------------
>UniRef50_B0T1I1(42-338:357) Thiamine-monophosphate kinase n=5 Tax=Caulobacteraceae RepID=B0T1I1_CAUSK  E=6e-14 s/c=0.27 id=24% cov=84%
-----------------LIERLLRPLTRGDaaALNLLDDAAVLP----SRPGYDLVITKDAMVAGVHFLAGEDLDVVAkrlLRTNLSDLAAKAAVPYGYFLAVGWPSGTTLTDRETFARGLAEDGELYDVNLLGGDT-VTTSGPM---VVSATFLGWTPSGDAVLRKGARVGDRLMVSGTIGDGWLGLLAHWGEVeDPDGGLVRRYRLPPPRLSIRDALRAYARAAADVSDGLLADAAHVAKASGLRVKVDLDRLPLSPGAR---NWLGAQPeagearMSLASGGddyEIVCAVDPTDVAAFQAA--AMAAGVPVRDIGEFVEGEGI------------------------
>UniRef50_D1PUY6(11-351:370) Thiamine monophosphate kinase n=6 Tax=Prevotella RepID=D1PUY6_9BACT   E=9e-14 s/c=0.24 id=20% cov=68%
-----------------LIDHITKDIQLNN--ASSIFGIGDDCAVMHYPNTEVLITTDMLMEGIHFdltyVTMQELGYKAAMENISDIFAMNGTPRQMTVSMAIGKRFKVEDIEAFYKGLRSACDKWSIDIVGGDTT----SSYTGLAISITCIGEARKEDIVYRNGAKETDLVCVTGDLGAAYMGLQLLEREKEVYyqqiddinrkikeaqkagneeavkhfqeqgshiANFQPDFAGkeyllerqLKPeargdMIQLLREhNIRPTAMMD-ISDGLSSELLHICKRSNCGCRIYEKNIPI-------------------------------------------------------------------------------------
>UniRef50_A3IWC4(457-757:765) Selenide, water dikinase n=3 Tax=Cyanobacteria RepID=A3IWC4_9CHRO   E=1e-13 s/c=0.27 id=22% cov=77%
------------------------------GLASPDDAAIIDIS----EQELLVETIDyfpSFISDPFVF-----GQITTNHCLSDLWAMGAKAHSVSAVITLPYGVDsvlEEILYQLLEGCLKILKQNQVSLVGGHTL-----QGEKLGFGLSCNGFILPNRILCKSGMQPNDKIILTKPLGI-GTLLAAEmiyqTKGNWIDNAIQSMLISNKKASEIFLQFEASACT-DITGFGLVGHLIEMMKASQVSVELNLDKIPI---LIGAIETIkqgitsSLHPKNLDNEtyltvnknikkspnysllfdpqtsGGLLASIPEENADRCLQELIRAGY-TDSQMIGKVI-----------------------------
>UniRef50_C6XIX6(5-312:323) Thiamine-monophosphate kinase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XIX6_HIRBI  E=1e-13 s/c=0.26 id=20% cov=87%
----------------DLIKTYFAPLAISPDAFGLKDDV---AALNPPAGRQLIITTDTLVESVHFLSEDPLETVAqklLRVNISDVLAKGGTPWAAVLSLTWPSGRDVRQLSSFADGLKADLEHWGISLMGGDTTSTSGPLTLGLTLLAHC----PQTGPILRSGGKQGDDIWVTGSIGDGYLGLKAAMGELSLSR--PEDVALLawryrvpeipdSAIAELISEVA--HASAD-VSDGLVADINHIAKASNLQAIINLDEVPFSSAAKLCLAEKKVSRLELvtkGDDYQSVFTAPPEAKAVILRA--SLQYGLEITKIGTMQTGQGVSLQRPNGTM---------------
>UniRef50_A9BIH4(68-356:727) Phosphoribosylformylglycinamidine synthase 2 n=1 Tax=Petrotoga mobilis SJ95 RepID=PURL_PETMO  E=1e-13 s/c=0.28 id=22% cov=71%
------------------------------------------------------------------------------GIVRDILAMGARPIALLDSLKFGNVFDpkvKNIFEGVVSGISDYGNSIGVPTVGGETSFNEIYSTNPL-INVMCVGVANKNHLASSHADGP-DKLLVyvgskTGRDGIHGASFASKKlSGKDDRPSVQvGDPFTEKNLIEATLEILKIKGVRACQDMGAAGVLsstSEMAYKGGVGCELYLDNIPKRQE--------DIEPWEIMlseSQERMLFLVNPGTEKKVEAI--CNKYLIDFAVIGKTISTPHYVVKENSEGKVLADLP---------
>UniRef50_A8SRC0(86-342:344) Putative uncharacterized protein n=1 Tax=Coprococcus eutactus ATCC 27759 RepID=A8SRC0_9FIRM  E=1e-13 s/c=0.31 id=23% cov=63%
-------------------------------------------------------------------------------------------------------------KKLLGKLAGICAECGVDIITGHTEV--NTAVFEPIISVTMMGKQsghSDDADLCRLKRPVGMDIVMCGQTGVGGTLQLYYDNQKElFERYSESYLRPVERMEELILLGRQVDIalehgsvyAHDISRGGVFAALWEMGDALKCGLEVCHDDIPILQETIEICEHTGDNPYMIDGCGAALFVVPDGEhlADKLYEA------GYEASVIGHLTENSDRVV-VHDEERRFLTPPR--------
>UniRef50_B9K5N4(20-309:328) Selenophosphate synthetase-related protein n=3 Tax=Alphaproteobacteria RepID=B9K5N4_AGRVS  E=1e-13 s/c=0.28 id=25% cov=83%
---------SGGIAAKHDIGSVTARL----GVKGKSVAVGDDCAALPEGDGYLLFAIEGfmnaFVAADPWFAGWC----GVMVNISDVVAMGGRPTAVVDAVWADGE---ADAAPVLDGMRAAAEAYGVPIVGGHTNI----RTDRSQLSVAILGR--AKRLLTSFDARPGDVLVAA---VDH-----RGRYRPPFDNWEAATDAPAERLRGDLEILPQIAeaglalAAKDISQGGIVGTAIMLAECSGVGIDINVAAIPLPEDVS-------LDRWlaTFPSFG-YLLSVPPEHVTAVLTRFETRDIT--AAIIGTVSVGSAVAITN--GSKRIV------------
>UniRef50_Q72LK3(31-305:311) Thiamin-monophosphate kinase n=2 Tax=Thermus thermophilus RepID=Q72LK3_THET2  E=1e-13 s/c=0.29 id=25% cov=69%
----------------------------------------------------------------------------VAATASDLLVKMGRPLGFTLGLFLPEDLEEGFVLELVRGAAEAAKRLGAFLLGGDT-----NRGVEVALTVSGYALAEAPL---PRKALPGDLLYLAGDrWGRTGAAIRAHYEGRSLEGfpKIREAAFYPLPRLELLALSGLLRGSLD-SSDGLAETLWQLSE---LGVRVELEVLPLYPDVLAFAgsEEAALElVLYGGEEFEAVLVVPQEGAAAVEAR--AKAKGLPLFRVGRVVAGEGVYLR-------------GAPLPR--
>UniRef50_C8QB92(66-298:319) AIR synthase related protein n=3 Tax=Enterobacteriaceae RepID=C8QB92_9ENTR  E=2e-13 s/c=0.34 id=24% cov=47%
--------------------------------------------------------------------------------LSDIAAMGGRPLAVVNALW------DDTLphaEQILQGMAAASRAYQVPIVGGHTNL----RSDQPQLAVAILGETRAP--LSSFAVQSGQTLMVAINLrGRwH-------PPGYNWDAATEAAPAALrqaWSLLPELAEAGLIRAAKDISQAGLAGTLVMMLESCDLGAELALEQIPIPDDV---------------------------------------------------------------------------------
>UniRef50_Q9HKS0(11-240:275) Thiamine monophosphate kinase related protein n=1 Tax=Thermoplasma acidophilum RepID=Q9HKS0_THEAC  E=2e-13 s/c=0.34 id=18% cov=55%
--------------------------------------------------------------------------------LSDIAAMAGHPISFMTAYSVSPDLDMEYLEAIEEGMMSVLRKYSVDFIGGDLK-----EGDDLTLVGIAIGRQTKKLTRKRSDIAKGQMVGYTNRIGRAASGYIFYKSGYDRKRGL-SMLLGVEPRISEAIKMSeyGARFMMDL-SDGLYASLDQMKQDYGVGFRIVRDEIAYDDSVNKASEISGSDVYDIA------------------------------------------------------------------
>UniRef50_D0LC24(45-276:361) Thiamine-monophosphate kinase n=1 Tax=Gordonia bronchialis DSM 43247 RepID=D0LC24_GORB4  E=2e-13 s/c=0.34 id=23% cov=57%
----------------------------------------------------------------------DVGARAIVQSAADIAAMGGRTTGVVVSIAAPPSTPVGTLLDLNAGMVDATHLLGARLLGGD--LVAAGQ---VVVSVTAVGAMDGRAPVALGGARPGDVLAVSGRLGacAAGLAVLSSDRPADVErwPDLVAAHRVPTPdlAQGPIAAARGAHAMTD-ISDGLVEELITMSQASGTQMSVDSSRVPRSDRVTALAAEWGVD-----------------------------------------------------------------------
>UniRef50_Q1GRI7(14-243:317) Thiamine-monophosphate kinase n=2 Tax=Sphingomonadales RepID=Q1GRI7_SPHAL  E=2e-13 s/c=0.34 id=24% cov=41%
----------------------------------------------------------------------------------------------------------------VEGLDGALRRFGVALLGGDTVRAPTGTPR--SFGLTAIGRAPEGGAPTRGGARPGDQIWVTGTIGNAGLGLAMRLGQVEPnETCLAAYCRPQPQLTFGQAVAPHVHAMMDL-SDGLLIDAQRMAAASGCELGIMMDAIPLS------------------------------------------------------------------------------------
>UniRef50_Q18DQ7(10-284:298) Thiamin-phosphate kinase n=10 Tax=Halobacteriaceae RepID=Q18DQ7_HALWD  E=2e-13 s/c=0.29 id=24% cov=61%
-------------------------------------QAGDDAAVISLDSVSLVITTDMLHET-TDFPDGttryTAGWRAVGASLSDIAAMGGQATA-AVAVYGAPAFDPDEIDSFIAGAIDVCDAANAQYVGGD-----LDTTSELTIATTALGTVTHPSYRHGARI--GDCICVTGNLGRTAA---------GLKAFETGDIAHANELFRftprvntGAALAKHTTAMMD-SSDGLARSVHQLASASEVGMSLHWDAIPTHPDVKEYVD----------------------------------------------------------------------------
>UniRef50_UPI0001C41E68(51-412:413) thiamine monphosphate kinase ThiL n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C41E68  E=3e-13 s/c=0.22 id=19% cov=67%
--------------------------------------------------------------------------------VSDLASMGAKNIGFLLNIAIPKDTSLDNFDDLICGIIRACDNYNIPLVGGDT-----NEASEIILSGTAIGQVEKGKALMKHGFKEGDLVSISDHLGYAalGFELLKIKEEnidkyndiifqiNKIDPTVK-DLALFKALKpEAKYEEGRILASHnsqenrisatDIT-DGLASEFYEIlnadkkyylfnkdteshnpndSNDSNdlnnqqnnqnntnnqdvideyddsnysKGIRIYEDKLPVDDEFKQIADVLGIDyldlFLHIGEDFELLFTINKELKSQLENDM-------NFYVIGEITNNNTVEIVLSNG-----------------
>UniRef50_B4X4C8(407-717:738) Selenide, water dikinase, putative n=2 Tax=Alcanivorax RepID=B4X4C8_9GAMM  E=3e-13 s/c=0.25 id=26% cov=79%
----------------------------NPGIEAGVDAADDAAIIDWPAGQRLVQSLDffpAFIDEPYLF-----GRIAALHSLSDLYAMNARPHSALANITLPwhhPRLQGRDLQRMMAGAVRELNAAGCTLVGGHTIEGPQMAA-GFTVN----GQADPAQLWHKRGARDGDRLILTKPLgsGVQLAALMQANSSNGaafhgpwLDTTLRHLLTSNHMAQRALQDVP-VNACTDITGFGLLGHLYEISQQSGVTLSVDCHKVPLLPGTlsliqQGVASTLSdanrqilvhcqqpqpvDDALLTAlcdpqTAGGLVFCLPADYAGQALQHLDRE--GIAATDIGKV------------------------------
>UniRef50_C5A4H7(47-329:334) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=Euryarchaeota RepID=PUR5_THEGJ  E=4e-13 s/c=0.28 id=24% cov=76%
-------------------------------------SALLDFGNF-----YLAMTTDGVGTKVLVaeavgkFNTIGIDMIAMN--VNDLLCVGAEPIALVDYLAVREP-DEKIFAEIAKGLYAGAEKAGIAIVGGETAVMP-DLINGFDLAGTAIGIVEKGKVITGEEMRPDDAVIGISSSGIHSNGLTLARKllipKYGLDYEYEG--RKLWEwlleptriyvrAVLELLERVEVHGLAHITGGGLIN----LKRLTNYGFSLE------MPPIEGIFKLIhenGV-PLEemfrVFNMGVgFVAIVPPEEKEEALGILNKY---YESFELGRVTKEPGIRVEN--------------------
>UniRef50_O29525(13-280:296) Probable thiamine-monophosphate kinase n=1 Tax=Archaeoglobus fulgidus RepID=THIL_ARCFU  E=4e-13 s/c=0.29 id=25% cov=31%
----------------KLVERLFGDE------DVITPAGKHDAAYVKIGNRLIVLTCD--TVNeksdfpPYMLPE-EMGWMAIAVTLSDVAACGARPLYFLSSISLK---SIEFFEDILLGIKRCADRFGVKVVGGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3V944(398-698:698) Selenide, water dikinase, putative n=3 Tax=Rhodobacteraceae RepID=A3V944_9RHOB  E=5e-13 s/c=0.26 id=26% cov=65%
----------------------------------------------------------------------------------DIWAMGATPQAATVQIILprmESALQQRTMAEITATTTAVMSEAGARIAGGHSAL-----GDELTIGFTITGLV--DRPITQAGARAGDALILTKPIGS--GTIMAGDMAGQARGADVIACLDLmvQSQAKAAAILHAAHAMTDVTGFGLLGHLRGICDASGTGAVLDWAQVPVMAGaavlsargvrstlfadnqagagvVEGAVPDLAYDPQT---AGGLLAAVAGHSADDLLGALTRA--GYTAAIIGQITDGSAISLR---------------------
>UniRef50_A6VQ54(23-285:366) Selenide, water dikinase n=13 Tax=Bacteria RepID=A6VQ54_ACTSZ   E=6e-13 s/c=0.29 id=23% cov=73%
-DTIRLtqySHGAGUgcKISPKVLGTILqtkLEQFIDPHLLVGNDTADDAAVYDIGNGVGIISTTDFFmpIVDDPF----DFGRIAATNAISDIFAMGGKP--IMAIAIL--GFPIKLLpaevaQRIVDGGRFACKQAGIALAGGHSIDAP-----EPIFGLAVTGMINTDKVKKNASAQAGCKLYLTKPLGIGVLTTAekkgkLKAEHQNLATQVM--CQ-MNLVGSAFSEIDGVTAMTDVTGFGLLGHLIELCEGSQLNAVVYMDKIHTLDGVRDYLE----------------------------------------------------------------------------
>UniRef50_A4A0I2(4-303:305) Thiamine-monophosphate kinase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A4A0I2_9PLAN  E=6e-13 s/c=0.26 id=24% cov=82%
----------------EFIQHLRKSLGSHDRLriGLGDDAAILDW----RDRDDLVVTTD-LISDEIDFRLAevdprRVGRKALAVNLSDLAAMGAEPVAVVVSLLLPRtppvGTALELAVQLYDGMLPLVEQFDCILAGGDT----NSWSGPLAINVTAFGSC-SDQPLLRRGAAPGDVILVTGEL---GGSILG--HHFDF--------------------TPRIAEARRLTRLGLAQVGMDISdgllldlsrllNESEVAGVLDLTSIPISDAAHRLSETSGRTPLEHAladgEDFELLLTASPEHAQQIVAD---DLLGTPVTAIGKIVAGAGMWAD-QVGGKKL--EPQGYL-----
>UniRef50_B8FWU2(29-333:340) Selenide, water dikinase n=24 Tax=Firmicutes RepID=SELD_DESHD   E=7e-13 s/c=0.25 id=27% cov=67%
------------------------------------------------------------------------GRIAAANALSDVYAMGGSPLFALNLVCYPEREDIQDLGEILAGGAEKLQEAGAVLCGGHS-IYDREPKYGLAVT----GRLNPRQIWKNNTPQPGDRLILTKPLGV-GIVMAALRGEMAEAAAVEAALASMQRLnkyaAEKARDFP-IHACTDITGFGLLAHTREMAGGS-TTIVLYPSALPYiaqaytyaqgylltaagqrnRNFMEGAVEFgdtpfplqeLMLDPQTS---GGLLLSVPGDCAQEALRAIQETE--PQAALIGEVLPRQ--------------------------
>UniRef50_B8J1Z5(31-334:356) Thiamine-monophosphate kinase n=5 Tax=Desulfovibrio RepID=B8J1Z5_DESDA  E=7e-13 s/c=0.25 id=28% cov=55%
--------------------------------------------------------------------------------VSDLAGCGARPLAFTLCLGLPAWVDMDWLNRFFSGMAELAGKHRIALAGGD---LSRSTSLHISITVWGEAAEPGSFLARGGSM-PGDILFLVGPLGlaRAGLALLEEQGREALHHWPAVCAAHLRPVPQVdaglMLSRAGYNArppalmdlsdgiLRDLPRllglsGELSATCPEKCTGLGAEIVLPRGRL--HPEVLHYAAATGKNPVYEA------------------------------------------------------------------
>UniRef50_A7VEH2(70-303:314) Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50 RepID=A7VEH2_9CLOT  E=1e-12 s/c=0.33 id=20% cov=67%
---------------------------------------------------------------------------------NKLRLGGYQPFALTDTVMMPEN-DEKRMKKILRELSDLAKEFHMDVVYGDTAI--SGIFKEPAVTVTMYGRRISQGEKNAK-IKPDMDIVMCGQAGILG-TLLRVRERKEelltryseeyLRTAEQFDrLLLVKDQGDIAMACGSIYVRHISTE-GVYGALWELAEAGNVGLRISHDHIPIMQETIEICEFTGDDPYRIDGCGAALFV----TADGGLLSDRLYEAGFEAAVIGRTTIGHDRVI----------------------
>UniRef50_A3PDW4(14-310:326) Putative uncharacterized protein n=1 Tax=Prochlorococcus marinus str. MIT 9301 RepID=A3PDW4_PROM0  E=2e-12 s/c=0.26 id=18% cov=84%
-----------GIESKKDIQSA-AKTFSHSPFSQLGKSAMLgdDAAVIPKQSGLLLMASEgispSLVEKEPWFAGWS----SVLVNISDIAAMGGKPLALVNS-IWSDKNDLEKHNQILSGMNFACEKFNVPMVGGH----SNQKSPYSALSVSILGLVDGPILSSRFAESEDELWIIANKDGcffkdypfwdaATKASATLLRKHF--------------SLIPFLAKKNIIHAAKDISMGGITGTAVMFAESAGKTIEIDLEKIQRPEGVTE------FDWLTCFPSYGFLCAIKPSKVPFLKEALRAYEELICCHVGNFKNGNSSVYIKNSNGAK---------------
>UniRef50_Q0F396(5-287:305) Thiamine monophosphate kinase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F396_9PROT  E=2e-12 s/c=0.27 id=24% cov=45%
----------------DLIDRCFAGRGGQPrtftRLGIGDDASVHQPAA----GMELVVSTDTSLAGvhwPTDLPLAVAADRAVCAALSDLAAMGAEALCCWLNVMAEDAGAVAQMG---DGATAALARFDVELVGGDTT---RSSCNALAVTVA--GQLPAGSAMRRSGAQAGDNIWLCGCVGFH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6AFK0(28-317:331) Thiamine-monophosphate kinase n=1 Tax=Leifsonia xyli subsp. xyli RepID=Q6AFK0_LEIXX  E=2e-12 s/c=0.26 id=26% cov=75%
-----------------------------------------DAAVLVAPDGRYVVTTDLMVHGPDFRLAWsspaDLGWKAAATNLSDVAAMGAVPTALVVAIAAPPALPVVALEEIAEGLRAACEalALGCGVVGGDLSASET-----LTLAVTAFGDLRGRSPVLRSGARPGDILAVSGRLGaaaaglrllfRHAVDAAGAPDRAAFErvaadhpDLVAAQLRPAPPIADgPLAAEAGATAMLDL-SDGLTIDARRVGEASGVAIDLDPDA-------------LGPDPrlaLTGGEDHSLLASFPPDAA---------LPGGF--RRVGAVLEGEGLFVGGRPFGER--------------
>UniRef50_B2A1F9(16-243:323) Selenophosphate synthase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF RepID=B2A1F9_NATTJ  E=3e-12 s/c=0.33 id=25% cov=53%
------------------------------------------------------------------------GQLAASNALSDIYAMGAEP--VTCMNLL--GFPIDKlsseiLNEILRGGHDKIQESGAALVGGHS-LEDNEPKYGLSVT----GTVSPDKVWTNSGARSGDVLILTKPLG-TGIVTTAIKGELAephHEHSVVEAMVTLNKTAKRVLEDFNVTACTDVTGFGLLGHALEVAKASSVDIELWEENIPLLPGTQEYAE----------------------------------------------------------------------------
>UniRef50_C1E7V6(449-749:804) Selenide, water dikinase n=4 Tax=cellular organisms RepID=C1E7V6_9CHLO  E=3e-12 s/c=0.25 id=23% cov=71%
----------------------------------------------------------SFVDDPYIF-----GQIAVVHALGDCWAMGAEPHAVLAIAQVPYGLEsqvEDELWQMMSGATAVLEEVGCALAGGH-----SCEGAELALGFSVHGVAKREKLMKKGGMKPGQVLIVTKPIGT--GTLFAADMRAKAEGRWVTKALDsmrkPSAVAAQLLVEHGAKACTDVTGFGLLGHLVEMCKGANLAAVLDLDEIPVLDGAEE-CLKMGItSSLQPANvrlsravanqdgiannprypliydpqtAGGMLAAVPKENAEACIEALRQAGYPSTCG-IGEIIEH---------------------------
>UniRef50_Q4JUX8(24-268:332) Thiamin-monophosphate kinase n=4 Tax=Corynebacterium RepID=Q4JUX8_CORJK  E=3e-12 s/c=0.31 id=24% cov=54%
----------------------------------------------------------------------------------DIQAMGARPTAILMAIATPGDLPLQTVADIARGIDEAASPWAAELVGGD--VVTSKD---LVISITALGEISGPaAALTLDGAGVGQRIIASGPIGYSAAGLAVLRHYGSRKAIPANDpilneladwhCAPrLEPGRGSVARATGASAMTD-NSDGLIVDLCAIAERSGVCLDLDGAALVPDEKLRHAAQMTGKNPL---------------------------------------------------------------------
>UniRef50_A8MHJ6(42-295:346) Selenide, water dikinase n=30 Tax=Bacteria RepID=SELD_ALKOO   E=3e-12 s/c=0.30 id=23% cov=55%
------------------------------------------------------------------------GQIAAANSLSDVYAMGGRPLTAMNIVCFPNCLDPKILNQILKGGADKVLESGALLVGGHT-VEDDEPKYGLSIT----GIVHPKKVWANSTAREGDYLILTKPV---GLGVLNTAIKADIATKEQYDGAVkvmsmLNKYAFEALENLDVSACTDITGFGFLGHVYEMAKGSGVSIEIFADKVPLIDGAKELATM-GIIP----------------------------------------------------------------------
>UniRef50_B2V0F0(32-338:345) Selenide, water dikinase n=4 Tax=Clostridium RepID=SELD_CLOBA   E=4e-12 s/c=0.24 id=20% cov=68%
------------------------------------------------------------------------GQVAAANALSDVYAMGGNPS-IAMNLIcFPSCLDISIMREILAGGYDKVKEAGAVIAGGHT-IADPTPKYGLCVS----GFARPEEILSNSNAKIGDVIILTKPL---GIGIMNTAAKAELIGenkikEVTSIMSTLNKYAKECTSGLEIHSCTDVTGFGLIGHGYEMASGSKKTIEIFSEYVPIIDGALDYAKM-GIIPEGMYNnldylkdkfvveanisqelqdvlidpqtSGGLLLSLPEKHAKEFLS--RIEKFTPYAKIIGQVLDKG--------------------------
>UniRef50_Q5ZUW5(45-352:358) Phosphoribosylformylglycinamidine cyclo-ligase n=24 Tax=Gammaproteobacteria RepID=Q5ZUW5_LEGPH  E=4e-12 s/c=0.24 id=26% cov=84%
--QVLTGIGSFG-AMYDL--KPFMEKFKHPVMVQSIDGVGTKTIVARMMQK---FDT--------------IGIDLVSATTNDIIVLGARPLTL-LDYIATDRLKPEYIEEIIIGMTQACLENNISLVGGETAEMPdtylKGEHDLVGIIT---GVVEKDEAILGKDITPGDSVLAFPSSGLHtngyslarkllfelgGYTVESQLDELDAtvgEALLVPHINYTNPVLHLLNNKIPIKGMAHITGGG---VLENIPRvlPNHCSVEINKNSCPVLPIfnvLKALGKLDDQEMYRTFNMGIgLVMIASPGVVSEIYTALKEFP-NFPVYEVGKVVSGK--------------------------
>UniRef50_UPI0001C41B3D(421-708:736) phosphoribosylformylglycinamidine (FGAM) synthase II PurL n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C41B3D  E=5e-12 s/c=0.26 id=23% cov=76%
--------------------------------KPGDDAAVLQ----IDDETAVALTADSNTVHTKLSPyDGGAGSVAEA--IRNVVSMGAKPYAIVDCLNFgnPETPEILWqFKECIRGMSDIAEKFEAPVISGN--VSFYNETEGIKINpTPAVGVIGVEKLSSIRTLPfknEGDKIIIIGktydELGgsEYHRAVHNLEQGEAPKIRIDDELAAANAVLDLIendgdyvkflegEDKLNIKATHDVSAGGIAIALSEMVMKGKLGCEIDISNVPAEENIS------DNDLLFSESHGRYIIAVDADKAEEIV-----NSIDIDAAIIGEV------------------------------
>UniRef50_C6A0I0(451-681:713) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Thermococcaceae RepID=PURL_THESM  E=6e-11 s/c=0.31 id=24% cov=65%
---------------------------------------------------------------------------AVAEVVRNLASVGARPLALvdNLNFASPERPEVYWsFIETIKGLADAAKAFGLAYVSGNVSFYNE-VGKKPIKPTpvvAGLGKVKLENITTMDFKDKGDLIAVVGTtkkelGGSELYRIFGINKGIAPRVDLEREKQNVEGILKAI-ELKLVKAVHDVSKGGLAIALIEMAISGNKGFEVDIEKVPAEG---------GLSPLEVlfsESHGRFLISFEEKNLEKIKAIFDEF------AVIGRVAEE---------------------------
>UniRef50_A9KR69(67-324:332) AIR synthase related protein domain protein n=1 Tax=Clostridium phytofermentans ISDg RepID=A9KR69_CLOPH  E=6e-12 s/c=0.29 id=18% cov=73%
--------------------------------------------------------------------------------VNNIYAKGGKPIAVSTSLTLRSHADEQELKLYSKELNRLSTLYSIPVLSGETMVGAGATQNTITIHATGkVNKQSNTMDKKQESIEDSAKeyqIVMSKYIGLSATKLLIESRKEKLKERLTESFLAGGKKIGELLSIQKemevstdfdILCSHDVSEGGIFAALWEVGESLQCGMEVSLDSILLIQETIEVCETLDLNPYLLYSGGCVLFVTKQGEA--LVEKL--NNEGIPASVIGKTTNSPDRIVRKEDEI-RYLEPFKGD------
>UniRef50_C7QH11(31-184:370) Thiamine-monophosphate kinase n=1 Tax=Catenulispora acidiphila DSM 44928 RepID=C7QH11_CATAD  E=7e-12 s/c=0.48 id=24% cov=31%
----------------------------------------------------------------------DIGHKAAAQNFSDIVAMGGVPTSLLLSMVLPGDLPVAWVEEFAEGVAGECARVGAIVAGGD---MVRG--DLITISVTVLGTLEGRAPVLRSGARPGDTVAVAGRLG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8X4R7(12-307:329) Thiamine-monophosphate kinase n=1 Tax=Desulfohalobium retbaense DSM 5692 RepID=C8X4R7_DESRD  E=8e-12 s/c=0.25 id=25% cov=84%
-----------------LIDRYFPNTHAHMPLGRGDDCAVLRAPDW------MCLTADMFVEDVHFrrtyFSPEDIGYKALAVNLSDIAGMGARPLGFALNLMATGRESDEFCEGLVSGMADLAREHDLPLVGGD---LSRGPALAVAITMWG---KSQKRFLLRRNCQPGDLLFCLGDVGlaRCGLSVLERDDEslrWRFPEAVEAHLRPQIRLEQAqtLGEFEQVRGLMD-VSDGLMQDLPRFV-GPGFGVEVFMSESEVHPEVvefaREFAGLPGVEQALLGGEDYALLGAAAPGASHFLE--REFPEILW---LGKVVERSGIYLDGA-------------------
>UniRef50_Q67KF8(96-351:778) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Bacteria RepID=PURL_SYMTH  E=8e-12 s/c=0.29 id=24% cov=71%
-------------------------------------------------------------VDP--FNGAATG---VGGILRDVFTMGARPVATLNSLRfgpLDEPKQRELLRGVVAGIGHYGNTVGVPCIGGEVYFDESYRGN-CLVNAMCIGILRPDRIHRGIAAGPGNAIMVvgnpTGRDGIHAASLLASAEfsgseaEAALPTVPVGDPFAEKMLMEACLELFETDAvvgIQDMGAAGLISSSSEMAARGGVGVELDVRKVPAREE--------GMEPWeFLLSESqeRMLVCVKKGREAEVEAICRK--WGVGCAVIGRVTDDGMVRV----------------------
>UniRef50_Q10VI8(430-753:767) Selenophosphate synthase n=10 Tax=Cyanobacteria RepID=Q10VI8_TRIEI   E=1e-11 s/c=0.23 id=23% cov=84%
--------GCGAKVTSRVLENVLHKI---PQEIRRDDiligmDTPDDAAVIRVPADRVMVqTIDYFrglLDDPYLL-----GKITANHCLSDLFAMGAMAQSGLAIATIPYAAPskqEDTLYQLLLGATEVLNQSGAVLIGGHTT-----EGEELAFGLTCNGLVSQKKLLYKGGMQPGDMLILTKALGT--GTLFAADMRLKargrwIESAIKSMLGSNQNAAQLLLEY-GVTACTDVTGFGLVGHLLEMLKGQRVGVELDMEAIPVLPGVAETLEQGIFSSLYPGNlqmsasiqnreqasmyplypllfdpqtSGGLLATVPANLASACLNALQQEYF--ETRIIGRV------------------------------
>UniRef50_Q0ATX4(3-298:315) Selenophosphate synthase n=1 Tax=Syntrophomonas wolfei subsp. wolfei str. Goettingen RepID=Q0ATX4_SYNWW  E=1e-11 s/c=0.25 id=24% cov=68%
------------------------------------------------------------------------GQIAATNALNDIYAMGGTPI-LALNVVcFPECADLQVLRKILEGGLSKVLEAGALLVGGHT-VDDNEPKYGLAVS----GLVHPQKIIANNGAQPGDLLFLTKPLGNGVIATsikaeMVSGEAYKEAIKWMS---MLNRESSQAMMEVGVNAATDITGFGLMGHLYEMAWGSDVQVEVFADKVPFMEGTLEYAG-LGLipggaynnrdylkdkveyagniDPLIrdlfFSPEtaGGLLIAVAEKKAGELLQVMEKR--GSFCNLIGRVRGEH--------------------------
>UniRef50_Q8TY09(38-341:724) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Euryarchaeota RepID=PURL_METKA  E=1e-11 s/c=0.24 id=19% cov=84%
------------RSTRHLLRQL-PSEADHVIVGPGDDAAVV----AIDDEWAVVVGIESHNhpsyVDP--YNGAATG---VGGIVRDVLSMGAFPIALLDPLRFGPldGERVPYLvDGVVRGISDYGNRIGVPTVGGELEFDPSYERNPL-VNVMCVGIVRRSEIVRGRADRPGDVLVLvgarTGRDGIGGAAFASEELGEESEEEDRPAVQIGDPFTErqliiairEAVERGLVKGCKDLGAAGLTCAATEMAADGGTGVEIDVFKVPLREE--------GMEPWEIMlseSQERMLLVVAPEDVDEVIEICRK--YGLEASVVGRVTDDGYLTVK---------------------
>UniRef50_Q8TY09(418-698:724) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Euryarchaeota RepID=PURL_METKA  E=4e-06 s/c=0.20 id=24% cov=57%
-----------------------------------------------------------------------------------------------------------QLRRSIEGLGKAAREFEVPVVGGNVSLYNEHEVDGPVNPTPVIGAVGVIRGLDyledfPREPEEGEAVIVLGETREELGGSLYLIEYHGIKGGKVPRVryreeRALHDLLRRIARKNMVSSVTDVSTGGLLAAVAELLGPVGASLSLSE----VPNSVSRW-DFL------LLSESHGRAIVTTDRPDDVLGA--AEEAGVPAQVVGEVTGDG--------------------------
>UniRef50_Q60337(8-303:319) Probable thiamine-monophosphate kinase n=9 Tax=Methanococcales RepID=THIL_METJA  E=1e-11 s/c=0.25 id=21% cov=70%
----------------EIIKKTL--KFSNENIVKGIDD---DCAIIKIDENfYLVATTDMMVKKahiPSILSPYEIGGRILTANVSDIASMGAKPLAFLVSISLSkEEANEKFIKELYSGLDDFSKLYDCPVVGGDT-----NRGDELILSGTAFGITDNPIY---RRGKVGDDICVTNDLGRVYCALtlyYMLKENKISYKEFERLCQKYPKIIEKLrKPIARIK------EGLLMNKLingcCDISDGLGKEItyfknfEIYSDRIfkLIPEDVIEFCDAFNLNPIKVA------------------------------------------------------------------
>UniRef50_Q2G9G0(38-245:304) Thiamine-monophosphate kinase n=4 Tax=Sphingomonadales RepID=Q2G9G0_NOVAD  E=2e-11 s/c=0.35 id=20% cov=60%
-----------------------------------------DCAVLDFGGETMVLTHDMMVEGVHWLPGQDMADVAwklVATNLSDLASKGAEPVGVLLGYTL----DNDEDARFIEGLGAALATFGVPLLGGDT-VSGNGPRS---LGLTALGRATSHPVPDRRGARVGDVLWITGPVGAAMLGFEALRDGTAADSTAFR--RPVPRLAEGRALAGMVTAMMD-VSDGLLIDAARMADASNVTFAIDSASVAFPP-----------------------------------------------------------------------------------
>UniRef50_Q2NEB6(454-692:723) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Methanobacteriaceae RepID=PURL_METST  E=8e-06 s/c=0.23 id=18% cov=51%
---------------------------------------------------------------------------AVLESINNAISMGARPIALVDCLNFgnpekPEVF--WQFKEAVSGMSDVAGKFNTPFISGN--VSFYNETEGVTVNPSPIvgtvGVVENTKIKTMTLKDDGDVILVVGntypelDGSQYYKHIHNVVQGYPPKIRLEEN-YNVSTTIEKLIPkyNDNITSVHDISKGGLIIALALMSIKSKKGVNVNISNIP--------------------------------------------------------------------------------------
>UniRef50_Q30RS2(3-234:275) Thiamine-phosphate kinase n=3 Tax=Campylobacterales RepID=Q30RS2_SULDN  E=3e-11 s/c=0.31 id=22% cov=42%
------------------LENYFISQFKSANIG--DDGAFIDG---------MVYSKDAFFENIHFKTSWmshyQIGYKSIMVNISDAVAMNATPKYALLSVAMPKDITKSQMRDLAKGFQDACAKYGVDIIGGDT--ISNIKLD---ITVTIVSK--SNKPLMRKGLKRGDLIAYSGTLG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5UM16(37-336:339) Phosphoribosylformylglycinamidine cyclo-ligase n=8 Tax=Euryarchaeota RepID=PUR5_METS3  E=3e-11 s/c=0.24 id=20% cov=67%
-------------------------------------------------------------------------------VVNDILCVGAEPIALVDYLAVEQPDP-ERAEEIAEGLVTGAKESRISIIGGETASLP-GIIKDFDLAGTGIGFVDVDKIITGEDIEAGDVLIGIESNGIHSNGYSLARKALfddaGFSIDdkmpncdttigeelIRPTELYVKPIVALFKEEYDIHGLAHITGGGF-TNLRRLKKGVGYDIYdlpeapeifklIYQQNVPLEEMYKVFNMGIGF-----------VVITNENEAEKIMETLKDYC---NCQIIGKVTDDEKITVKTFEGSE---------------
>UniRef50_A1VE87(46-339:351) Selenide, water dikinase n=13 Tax=Desulfovibrionales RepID=SELD_DESVV  E=4e-11 s/c=0.24 id=26% cov=73%
-----------------------------------EDAAIVRVPGGKAIVQTLDFFT-PIVDDPYLF-----GQIAAANALSDVYAMGGEPwCALNIVCFPVKELPEEILADILRGGADKVREAGAVLVGGH-----SIEDESIKYGLSVTGIIDPDCYATNTGLRPGDVLLLTKPLGSGVLATAVKAGWDGFEAheqELGRWGAMLNRAGGRVIRELGLAAATDVTGFGLGGHLLEMANASNMSVHVDVSTLPlmpavldlvatgllpagshanrhfcsgnvsVHPEVDSLLVDIVFDAQTS---GGLILAVPPHLVDDACSILRAE------------------------------------------
>UniRef50_B2A162(91-355:368) AIR synthase related protein domain protein n=3 Tax=Clostridia RepID=B2A162_NATTJ  E=4e-11 s/c=0.27 id=26% cov=67%
------------------------------------------------------------------------------GAMRDVVAMGARPLFIMD-FVgtrpLEEevivgpcGFqekctcgncetmtSQERLNIMLKGIKDMCSTMDVFVAGGGFSTSFSDIVPAVVLTV--IGQQITEEPLTKPAKEAGDKIIIIGETGVDG-------NDTLYRAGLVSELLPAQALFEEEKttmeatlsafKTGKVKACSDLGAAGIGAAVCESARFGGLGAEVELDKAPVKtenisPEERLICETQ----------GRMLLQVAPENVDEVLEAI-SAKNGQGA-VIGEITAENQSIFK--YQGERIATIP---------
>UniRef50_Q46F25(44-350:715) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Methanosarcinaceae RepID=PURL_METBF  E=5e-11 s/c=0.23 id=22% cov=86%
--------------------KTFTSKGENVIIGPGDDAAIIKF----DDGYVLAIGMESHnhpsYVDPYNGAATGIG-----GIVRDIISMGARPIALMDPLYfgpLDTPKNMFLFEQIIKGIAGYGNCIGVPVVNGETFFDRRYSGNPL-VNVVAVGLCREEEVITARSQKAGNKLVLagssTGKDGLGGASFASRDLSESAEAEDRPSVQVGDPYTEKLVIEMTLEAMekgyikscKDLGAAGLGGASAELAAKGGLGAHITADAVTQREPNMNAYEIL------LAeSQERMVFEVAPEDVDAVLALVAKYDL--NGAVVGYLTEKPNYTVE--FKGEVVVDIP---------
>UniRef50_A8V5R7(1-193:205) Thiamine monophosphate kinase (Fragment) n=1 Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8V5R7_9AQUI  E=6e-11 s/c=0.37 id=20% cov=54%
---------------------------------------------------------------------------------------------------------------------EACDYYNCSVIGGNTSASEEIILD-LFI----VGQTERPVL--RKGAQEEDILLVSGHTGlsRAGLELLLMDKNYyeDFEERLiKTHTKPVVPaeLSEKIMKYANSCV---DISDGLVADLGHLQKASSVKVVIEKDRLPVHPDLEKFCQKYNKNPyeyiLYGGEDYQLLFTAKPENIDKF----------ENCFQIGYVEQGKGIFIKEKTG-----------------
>UniRef50_B4S641(16-310:371) AIR synthase related protein domain protein n=1 Tax=Prosthecochloris aestuarii DSM 271 RepID=B4S641_PROA2  E=6e-11 s/c=0.24 id=18% cov=49%
--------------------------------------------------------------------------------VSDLASTGCEPLSISLSIDAPSDMKLSELVEFYSGISSACQEFNISISGGNIR------ASKVFAThGTAIGLLERsKASITRKNCSKNDILI---SIGDNGAFIsfYLKAKKCGFDSLLPNEKEKLIKPYSQLRAVRIINqegllsSASDNSDGILGSIMN-ICERSNCGFLINFDDIKIP------------------------------------------------------------------------------------
>UniRef50_A3EPZ4(32-306:335) Thiamine-monophosphate kinase n=2 Tax=Leptospirillum sp. Group II RepID=A3EPZ4_9BACT  E=6e-11 s/c=0.26 id=23% cov=66%
--------------------------------------------------------------------------------LSDVYVKGGTPVSALVALGIPKNFPEERIFSFYEGLADACRRFDCPVVGGDISR-ATGGFDAV---LSLLARSPAGRFPGRDGLLPGDMLYLLGrpGLAKAGYSALLsgLSDHQAMAESVSAFCRPrTYPWFSELVNAEDQVVATMDTSDGLGQAIFAMADQSGVSVRLDppENWL---DHLQRPSSLLGQDPFGMAWDGgedyDILFAVRPGVGGDAISRIQEQIRGEPEKLIplGEVV-----------------------------
>UniRef50_D2PDK4(9-298:316) AIR synthase related protein domain protein n=9 Tax=Sulfolobus RepID=D2PDK4_SULIS  E=6e-11 s/c=0.24 id=19% cov=83%
---------------HEFIKRYIKNYVDIKLL---DDVFIHEKRGYKVDGFKL-----SYTF--PFMSLYDIGWKAISASTSDIIAKGVKPEFYLISLGLPPDFDVNKAEELIKGISDAIHYYGGRYIGGDLNDSDSSGWVDVFVE----GEVL--CDISNKDIDDGDLLVVGDYIGYTTNVFISYINNFNIQILPESLLKVKHPIVRKSLLFfmkkycKFIKYSTD-ISDGLMVSLYKIIDNFDLGINITE--IPIDKNVfntlKLRLNLTELDILKHAGEEflPLLIIDKNSPVKEMLNELQ--YLAFNPLIIGQVIHEKKVVI----------------------
>UniRef50_C6JD17(14-202:208) Putative uncharacterized protein n=1 Tax=Ruminococcus sp. 5_1_39BFAA RepID=C6JD17_9FIRM  E=8e-11 s/c=0.37 id=24% cov=48%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------LKPGDELVVACPVALKGTSViaknkkdkLAERFSAGFIQNCVSLrddygAGSIVWKIAQEADASALYAMG---EGGFLSALWKMAEASEVGLEADFRKVPIRQETIEVCEIFDLNPYKLQADGAVLIGIRGGEA--LVQRLRNE--GFMAEIIGQTNSGNDRLLYSG-GSARYLERPAEDEL----
>UniRef50_Q1IXX3(92-353:355) Phosphoribosylformylglycinamidine cyclo-ligase n=4 Tax=Bacteria RepID=Q1IXX3_DEIGD  E=8e-11 s/c=0.27 id=27% cov=71%
--------------------------------------------------------------------GADI----VNHCVNDILVQGARPLffldYVAMGRLLPE-----RVAEVVTGAARACEALGVALLGGETAEMPGVYVEGeLDIVGTIVGVVDRHKLIDGARLQPGDVVIALPSTGLHTNGYSLARMALadldweearaDLGGERLADLLTVphrayLGAFDALQAAGvDVRGMAHITGGGLVDNPPRI-FPAGVGMRVNTASWTVPPLFELIVRQAGVareEAFRALNMGVgFLFIVPAAQGEAALASLRGA--GESPWVIGEMVPGSGVTFDGV-------------------
>UniRef50_C0Q953(44-343:349) SelD2 n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0Q953_DESAH  E=8e-11 s/c=0.24 id=23% cov=67%
------------------------------------------------------------------------GQIAAANALSDVYAMGGTPKTAMnlVAFPVKE-MDISVLRQIIQGGIDKLVEAEVVLLGGHS-IEDKELKYGLSVT----GFVHPQKVLIKGNLNPGNQLILTKPLG-TGIintAIKAAMASQALTDTVTRLMATLNRQAADIMSGFDVTACTDVTGFGLIGHLAEMILGSGMTVRLFSKNVPVIQEALTFASM-GLipagayknrefretmtqfsgnvdqslqavlvDPQTS---GGLLISVKASQASQLLSALKNAGI-SDAALIGEVIDG---------------------------
>UniRef50_A8HRC1(77-408:415) Selenide water dikinase n=1 Tax=Azorhizobium caulinodans ORS 571 RepID=A8HRC1_AZOC5  E=1e-10 s/c=0.21 id=22% cov=87%
----SLAHGGGcGcKLAPSVLQELLAGAPAAQPYAQLLVGmeTGDDAAVWDLDGETcIVATTDFFmpvVDDPDHF-----GRIAATNAISDVYAMGGTPIMALAILGMPLGkVDTGIVRKILEGGSAACAAAGIPVAGGH----SIDSVEPIY-GLAVIGTVRKALVRRNADARPGDALILTKAVGVGVYSAAFKKEALSSDAydEMIASTTLLNKVGSALAKDSAVHAMTDVTGFGVIGHALEVARGSKLAVTIEADRVPLMAHAEALVR-QGFvtgasirnwasygaearlpadfpewrrhlltDPQTS---GGLLVSCAPEEADRLVEEIQAAGY-PNARRIGAVTEG---------------------------
>UniRef50_A3EVN2(47-361:737) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Leptospirillum sp. Group II RepID=A3EVN2_9BACT  E=1e-10 s/c=0.22 id=25% cov=77%
--------------------------------------------VHVSDGLSLAFKMESHN-HPSFlepFQGSATG---VGGILRDVIAMGARPVALANSLVfgsLRHPKHRTLFQRVVEGIAGYGNPAGIPTVGGEIWFDDRYQ-HNILVNVMAVGIVNNNEIMSAKASQKGLLAIYignrTGRDGVSGAAMASrgfSKDGADLRPQVQiADPYAGKNLMEATLEIAR-KKLADSIQDmgaaGLTSSSTEMAGRAGLGMELDVSCVPLRDKTMEPWEIL----LSESQERMLVLSC-PENAEKILDIARAWHL--SAAIVGRTIQEPNFVV----------------------
>UniRef50_Q58811(88-367:452) Uncharacterized protein MJ1416 n=3 Tax=Methanocaldococcus RepID=Y1416_METJA  E=1e-10 s/c=0.25 id=19% cov=81%
--------GEGDFFVHREIARIVKSTKVKAYVSAEEQD---DAGIVRADAKYIVAAIDgthSRLSDFPFLGGFHVTRAA----LRDIYVMGAEAVALISDVHLADDGDVGKIFDFTAGICAVSEAVNVPLIGGSTLRVG-GDmviGDRLVSAVGAIGVIKEGEPTARRNAEVGDVILMTEGSGGGTITTTALYYGwFDVIYETLNvDFIKACQNLIRSGLIKKIHAMTDVTNGGLRGDAYEISKTAKVSLIFDKEKVykTINPKVLEMLEVLNIDPLGVSTD-SLMIICPEEYADDI-------------------------------------------------
>UniRef50_A7BD01(4-288:331) Putative uncharacterized protein n=1 Tax=Actinomyces odontolyticus ATCC 17982 RepID=A7BD01_9ACTO  E=1e-10 s/c=0.24 id=25% cov=68%
---------------AELSEAQLVSHFREsfPRGERTMIGIGDDCAQVAAPEGSFIVTTDVMVEDQHFHlswsTGYEVGARVAAQNLADIDAMGGRPSALVASVVAPRDMDADVFLDVVRGLGDRAREVGAGVVGGD-----LSAGEKLVISITAFGYCPGPV-VRRDGARPGDVVAVSGTLGYSYAGLDLLEGGYvDPSSRGVEQLGDLAPFIETYRAprpplgsgvaaaAAGARAMMDL-SDGPATDAGRIAQASGVVVEFNRDAI---------------------------------------------------------------------------------------
>UniRef50_Q8TV42(21-278:302) Selenophosphate synthetase-related enzyme n=1 Tax=Methanopyrus kandleri RepID=Q8TV42_METKA  E=2e-10 s/c=0.27 id=26% cov=77%
------------------VDDVKVVRLLPEFGRAEVGLADYDDAAVVRVDGKLVVSSDG----PYAFRLVR--KSALVHASTDVLVAGGEPRFAVDTIIAP--TEKGALEA-ARRIGRQARALGIEILGGNT--MIEDDVEEPKVSLTVMGPLVAPEPITDCGAEPGDSVLLVGEP-IHG----SFQERME-------RARRLFDTFPELARRGLVKAAKDVTKGGLVAMAALVCAKSGVGMDL--NSVPYSSITR--------------NWDNVLAVVSPDDVEEVLNV--CAERGCPVTMLGEVIEEPVLRIAGR-------------------
>UniRef50_Q0AFI6(27-342:349) Selenide, water dikinase n=3 Tax=Proteobacteria RepID=SELD_NITEC   E=2e-10 s/c=0.22 id=26% cov=81%
---------------HRILQQVRFPAAHSALMVDGryfDDAAIYKINEQTALVQTLDFFT-PIVDTPRLF-----GEIAAANAISDVYAMGGRP--VTAMGIL--AFPLATLSEhiivdVLQGASDKIAEAGANFVGGH-----SIDDDTLKFGLSVTGLVNPQQVWTNANAQSGDHLVLTKALGTGTLTAGIKRQQLqekDIMDALES-MAAINNVIDYLSPdlLAAIHAATDITGFGFSGHAMQLANASNVTLSIATGNLPRFDK-AFYClknsfltkahrtnaeyttphiDDAKLDALYklLIHDpqtsGGLLLSVVPEASQLVLQALRT--YFKPAAIVGTV------------------------------
>UniRef50_B5YKD2(10-314:333) Thiamine-monophosphate kinase n=1 Tax=Thermodesulfovibrio yellowstonii DSM 11347 RepID=B5YKD2_THEYD  E=2e-10 s/c=0.23 id=18% cov=53%
--------------------------------------------------------------------------------VSDIYAMGGDFKGFLFSAGVPETVSDQDFKELFDGIEDALKHYGGFLIGGDLSRSKN-------IVLSGFAVGEAEKPILRKGAQAGDLIFITSYLGlsSAGLNLLnnLSDDEKRFIKSIRNfkNCKeypdrllkfkgineilerHLMPIARKPDKFKHIaKAMMD-ISDGLLIDLHRLCEENKVGAEIYLDQLPIHPAITKIADYLNIEP----------------------------------------------------------------------
>UniRef50_C7BHY4(69-293:351) Putative uncharacterized protein n=1 Tax=Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949 RepID=C7BHY4_PHOAA  E=2e-10 s/c=0.31 id=24% cov=52%
----------------------------------------------------------SFVANHPYFAGWS----AVMANISDIAAMGGRALSVVNSFW---HTSSEHAQLLMQGMQDACRAYGVPLVGGHTNL---GVVYQPTLSVAIQGI--ARKLLSVLHVKPQQKILI----------ALNLQGKFHSNTtywkcfERVSDhiLQSQIALLPQLAEANLVHAARDISNAGILGSLLMLLEATASGAHINLDAIPKPDDV---------------------------------------------------------------------------------
>UniRef50_A5VHT8(446-717:742) Phosphoribosylformylglycinamidine synthase 2 n=50 Tax=Bacteria RepID=PURL_LACRD  E=3e-10 s/c=0.25 id=22% cov=63%
--------------------------------------------------------------------------------------SGAEPLAITDCLNY--GDPTDpeifwELHQSVQGMADACREFNTPVISGNVSLYNENNGQAIH-PTPMVGMVGLikniDRVIPSFVQHPGDKVYLVGqTRDDYAGSELQKMMTGDISGIVESfDLHHVHQYMQRLLttmENGLVSSAHDLSEGGLGVALAETVFKTDLGLKIDLAD-------QHTARLFSETP------GRFIVTVAPEKATEFEQVL-----GKDAHLIGEVTNSHWLMVKLANG-----------------
>UniRef50_D2R1W0(3-295:306) Thiamine-monophosphate kinase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R1W0_9PLAN  E=3e-10 s/c=0.23 id=24% cov=84%
---------------QQIVSAIKHRVLPHPALvvGIGDDAAI----TRVTPGKQLVTTTDMLMDGVDFLLASTdpvlVGRKSLAVNLSDLAAMAAVPVGAVISLALPRQGGEQLVRQLFDGILPLAAEFQLAIAGGDT-----NSWDGpLAISITVWGEVEPGEAWLRSTARVGDKLHVTGAL---GGSILERQFTFT----------PRVNEAQQLRRSAQVTAAMD-ISDGLLIDLARLCEASQCGAVLDLDKIPVHaDAVRLSLQE---HPTATPDELQAFalehALADGEDFELLLTIAPSDPLA--AQSIGEITSARGIFARAADGSLRAL------------
>UniRef50_Q8DIA7(54-353:761) Phosphoribosylformylglycinamidine synthase 2 n=16 Tax=Bacteria RepID=PURL_THEEB  E=3e-10 s/c=0.23 id=24% cov=83%
---------------SRLLLKQFPTQGPRVLVGPGENAGVVDLG----DGLRLAFKIESHnhpsAIEP--FQGAATG---VGGILRDIFTMGARPIALLNALrfgDLKEAKTQQLVKGVVAGIAHYGNCVGVPTVGGEVYFDPCYAGNPL-VNAMALGLMETPEIVKSAASGIGNPVLyvgsTTGRDGMGGASFASA----ELTDESMSDrpaVQVGDPFVEKCLieacleafQTGAVVAAQDMGAAGLTCSTSEMAAKGGVGIELDLDKVPVREQ-----GMVPYEFLLSESQERMLFVAAQGREAELIEIFQR--WGLQAVVVGRVIAEPLVRV----------------------
>UniRef50_UPI0001C1612E(78-339:343) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Nostocaceae RepID=UPI0001C1612E  E=5e-10 s/c=0.26 id=23% cov=68%
--------------------------------------------------------------------------------VNDVLTSGAEPLFF-LDYVATGKLEGEQLTQVVSGIAQGCKLAGAALLGGETAEMPGfyqvGEYD---LAGFCVGIVEKSKMLDGSQVQIGDLVMGLASSGIHSNGLSLVRKIIS-DGGFAWDHTPelfhgktlgstfltptriyVKSVLSALHQGLEIHGMAHITGGGLPENLPR-CLGSNQSVKVHPASWPIPPVFKWLADFgsVGAEAMYNTfNMGLgFVLILPPTQAQQAITHFQSQ--HIPAFTIGEVVGGSGELIA---------------------
>UniRef50_A6X235(66-361:363) Phosphoribosylformylglycinamidine cyclo-ligase n=416 Tax=cellular organisms RepID=PUR5_OCHA4  E=5e-10 s/c=0.23 id=27% cov=68%
--------------------------------------------------------------------------------VNDLVVQGAEPLFFLDYFATGKLSPDQGVD-IVAGIAEGCRQAGSALIGGETAEMPGMYRDGDYdLAGFAVGAAERDRLLPRGDIAEGDVILGLASSGVHSNGFSLVRRIVELSGlGWKSD-APfqpgatlgealltptriyVKPLLAAIRASDGIKALAHITGGGfpdnIPRVLPE-----GLAAEIDLESISVPAVFSWLAKTGGVEPnemLRTFNCGIgMIAVVKPEKVEEVVAALAAE--GEKVVTLGQMVkrDKDGVVYKGTL------------------
>UniRef50_A4VKS6(11-265:344) Selenide, water dikinase n=2 Tax=Bacteria RepID=A4VKS6_PSEU5   E=5e-10 s/c=0.27 id=23% cov=69%
------SHGAGcGCKISPKVLDVILAGSGAQNLDPRlwvGNASRDDAAVYGIDEERGVVSTTDFfmpIVDDPF----DFGRIAATNAISDIYAMGGDPL-MAIAIL---GWPVNVLppevaREVIAGGRAVCDAAGIPLAGGHSIDAP-----EPIFGLAVSGLVNKRQIKRNDTATAGCKLYLTKPLGIGILTTAEKKAKLRVEDvGLARDwMCTLNTAGSRFGKLEGVRAMTDVTGFGLLGHLVEMADGSGLTAEIEYARVP--------------------------------------------------------------------------------------
>UniRef50_Q31DG0(26-253:328) Thiamine-phosphate kinase n=6 Tax=Prochlorococcus marinus RepID=Q31DG0_PROM9  E=6e-10 s/c=0.30 id=18% cov=29%
----------------------------------------------------------------------DLGWKAVVSNISDLLSSGSKKtIGITISLILPAKTEWVWVEELYKGINKALKEYGGKILGGD---CSKGNQKTISITAFGI---QGELELRRNACKPGDIILTTG------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A2SPR4(87-328:331) Phosphoribosylformylglycinamidine cyclo-ligase n=4 Tax=Methanomicrobiales RepID=A2SPR4_METLZ  E=7e-10 s/c=0.28 id=23% cov=67%
--------------------------------------------------------------------------------VNDMYVMNIEPIAF-VDYIATEGINTEQMIQIGVGLNEGARLSNLNIVGGETATL-KGMINGLDLAGTCLGVQDKDKVVTGEKVAPGDIIIGVASTGVHSngytLARKVAEENGGYATVLLSGrtvgeaLLVPTRIYSEVLDVCSkavVHGMCHVTGGGLLNFL----RISSYGFAI-EDPLEVPEILAWIAEKgnLEMNELYRTfNMGMgFAFIVPKESVETVLSMVEG------SKVVGRVIEEHKVTLKGV-------------------
>UniRef50_A4S9M0(450-753:796) Predicted protein n=4 Tax=root RepID=A4S9M0_OSTLU   E=1e-09 s/c=0.22 id=23% cov=70%
-----------------------------------------------------------FVDDPYIF-----GQIAAVHALGDCWAMGADPHAALAIATVPYGLESQVEETLYQMMAGACdilRDAGCGLAGGH-----SSEGAELSLGFSVHGAAPREKLMKKGGMRAGHKIIITKPIGT--GTLFAADMRSKAQGRWVSNALDsmrqPSAVAARTLFEHGATACTDVTGFGVLGHLVEMCKGSSAACVLDMDALPVLPGALECVEIgitsslqpanvrlaraianpaavsgaarypLLFDPQT---AGGMLASLPSASADAAVEALKRAGY-EHTTIIGEVLE----------------------------
>UniRef50_UPI000050FADA(32-272:362) thiamine monophosphate kinase n=1 Tax=Brevibacterium linens BL2 RepID=UPI000050FADA  E=1e-09 s/c=0.28 id=25% cov=29%
--------------------------------------------------------------------------------LSDVCVMGAKPHGLLVSLAVPNSTEIEDLEALFAGIVAEAARAGealgceIPIIGGD---LSSSGLIVVAITalgtvggsgtgtaASSAGTHGSGAAITRAGAQPGDSIYLAGTIGR--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7NGL3(26-260:327) Thiamine-monophosphate kinase n=1 Tax=Kytococcus sedentarius DSM 20547 RepID=C7NGL3_KYTSD  E=1e-09 s/c=0.28 id=25% cov=55%
-----------------------------------------------------------------------VGAKAVAQNLADVTAMGGRCTSMVLTLVADAHTPVAWVEELAVGVGERAREAGVAVTGGDLSSAPAGTR---MVSITALGSLDGPPVLR-SGARAGDQLAVSGPLGRsaAGLALLQAGRTQAEPGTAAAEClehhrAPrVDPGAGQLAAAAGATAMLD-VSDGLGRDGARLATASGVALLLDREAL--GGDVRRAWEALG-------------------------------------------------------------------------
>UniRef50_Q1NV35(16-238:322) Selenide water dikinase n=2 Tax=delta proteobacterium MLMS-1 RepID=Q1NV35_9DELT  E=1e-09 s/c=0.30 id=21% cov=54%
------------------------------------------------------------------------GRIAAANALSDVYAMGGKPL-LAMNLVA---FPIKRLDckilkEILRGGLDALNEAGTLLVGGH-----SIEDEEIKYGLSLTGTVHPNRLLLNSGAQPGDQLLLTKPIG-TGILATAIKGGLAdgrIEEMIGQVMVTLNREAARIMITSGANACTDITGFGLLGHLHEMAAASSVAIGVDCRQVPLLPQVMHFAEM---------------------------------------------------------------------------
>UniRef50_D2RQG9(7-296:307) Thiamine-monophosphate kinase n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2RQG9_9EURY  E=1e-09 s/c=0.23 id=26% cov=81%
-----------------------LSLLEGELEAAGDDAAVVDD---------LVITTDMLHER-TDFPTGttryTAGWRAVGASLSDVAAMGADATAAVAAYAAPE-FDRDELLAFVRGARDVCNRVDAAYVGGD-----LDGHSEFTVSTTAVGRSDDPVRRS--GAEPGDLLCVTGTLGRSAAGLelfgRSAREDSASDDDSgverANDLFRFEPRVAAGAALAPHATAMMDSSDGLARSLHQLAEASDCGFAVDSEAVPVAEALFELADGEGTdaDPLERAiafgEDFELVATLPESALETVRAAID-----VDLSVIGSVTEPvEGITLDGE-------------------
>UniRef50_B0N3F7(171-414:426) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=Bacteria RepID=B0N3F7_9FIRM  E=1e-09 s/c=0.27 id=22% cov=29%
--------------------------------------------------------------------------------VNDIVVMGAKPLAV-LDTIVCGNAEKETIASLVKGISQACQNNECSLVGGETSIQPQVVEHGVYVLTSSIaGIVAKDKVIDGSKISAGDVILAIASNGLH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2VMQ3(391-731:737) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VMQ3_NAEGR   E=1e-09 s/c=0.19 id=21% cov=89%
--------GCGCKINSRLLDSILQKLPKQPENNSVLVGnSTCDDAAVYKINDHVAIvsTIDFF--APIVDNPYDFGAIACANALSDVYAMGGKPQtALSVVAFPSRTLPIEILQEILRGSIDKANEAGVAIVGGHS-IDDEEPKFGMSVN----GIIHPDKIFRNVGCEEGDLLFLTKRIGTGVITSAMKLGNVPYESETaQSAINSMKTLNRdtsyVLREMKSVSSCTDVTGFGLLGHLKEIMKGSreiceenkDLVAQLNAKQIPLLDSsclslmrivipggtktnlenVQQFVEFASTlskeEQLILADAqtsGGLLFTISPDEEEKLVNSFKEKNL--NLWKIGEIVKKPNSVL----------------------
>UniRef50_C0C1G4(25-286:294) Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM 15053 RepID=C0C1G4_9CLOT  E=1e-09 s/c=0.25 id=21% cov=74%
-----------------------------------------------------------------------IGVHALAESLNELAAAGAGAVEARVHIMIPDGYGRPRLAAVQKLIEKACGARGVTLIFLEQYKTPAAALPLVSVTCTG------TAEYTDRVIRPGQDIVLTKWAGLGGMVrILQEKED-----ELEERFAP--AFIKQIKEYAGeifageeLPAARqmgvsvfcQVTEGGIFAALWNLAREAETGLSVDMKKIPVRQETIEVCENYRLNPYQLMSAGSFLMVADNGR--ELARELTGR--GMKAAVIGRMTDNNDKVIQNG-EEIRFIDRPAPDELNKI-
>UniRef50_Q3ANP7(72-354:768) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Bacteria RepID=PURL_SYNSC  E=1e-09 s/c=0.23 id=23% cov=76%
------------------------------------------------GGHRLAFKIESHnhpsAVEP--FQGAATG---VGGILRDIFTMGARPIALLNALRfgpLEDPANVGLMEGVVAGIAHYGNCVGVPTVGGEVAFDPSYSGNPL-VNAMALGLMETEEIVKSGAIGVGNPVVyvgsTTGRDGMGGASFASAElsaDSLDDRPAVQvGDPFLEKGLIEACLEAfasGDVVAAQDMGAAGLTCSCSEMAAKGGLGVELDLDRVPARE-----TGMTAYEFLLSESQERMLFVVKAGREDALMQRFRR--WGLQAALVGKVLQEPIVRV----------------------
>UniRef50_UPI00019733F3(12-195:203) hydrogenase expression/formation protein HypE n=1 Tax=Clostridium sp. M62/1 RepID=UPI00019733F3  E=2e-09 s/c=0.36 id=26% cov=51%
---------------------------------------------------------------------------------------------------------------------------------------------------------------RPGFLKPGQDLIVAGSIGLTGAAAaarageKALRERfsasyaerlLSLDKDAENFAQ--NRLGEAFFREAGVTEAEPAEDGGIMNSLWNLLEAYGLGCTIELRAIPILQETVEVCEVFDINPYRLSSGGCLLMAADNGF--SALNALRKR--GVEGAVIGKVEKGIARRILNG-ETETFLDRPKPDEIEKI-
>UniRef50_B0TAU5(15-317:322) Selenide, water dikinase n=7 Tax=Bacteria RepID=B0TAU5_HELMI   E=2e-09 s/c=0.22 id=23% cov=68%
------------------------------------------------------------------------GQIAAANALSDVYAMGGRPvTALNLVAFPTKTLPMKVLGEILRGGADKVREAGAVLLGGHS-IEDKEPKYGLSVT----GVVHPDRVWTNGGARPGDGLILTKPLGIGIISTAIKKGKASPDAVAAATEAmtALNKTAAEVLSDFSVGGCTDITGFGLLGHGLEMARASRCSLRIHAGKVPIIPEARDYaiagyvpggskCNLSTVSPqLHLAADlqpetgilladaitsGGLLVSLPEKEVEAAIAALHNAGV-TSARYIGSVS-----------------------------
>UniRef50_D1C434(88-341:363) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Sphaerobacter thermophilus DSM 20745 RepID=D1C434_SPHTD  E=2e-09 s/c=0.26 id=25% cov=63%
--------------------------------------------------------------------------------VNDILACGARPLFF-LDYIAAERFPEGLIEALVRGMTDACRKAGCALIGGETAQLP-----GIYQPGTydlagfIVGSVHRDRIVDGATIRAGDLLVGLPSSGLHTNGYSLARAAFGLDPK---DAAarerlaatPAWadrplgelllephrsylPVVEPLLDTGVLRGMAHITGGGIAGNVGRvIPEGLEAVIDVRSWEPPaLFRGLQQAGNIDSAEMYRVFNMGVgFVLIAAPGDAQQLAAQLEG------ARIIGEV------------------------------
>UniRef50_C7RG06(36-326:337) Selenide, water dikinase n=2 Tax=Anaerococcus RepID=C7RG06_ANAPD   E=2e-09 s/c=0.23 id=24% cov=54%
------------------------------------------------------------------------GQIAAANALSDVyAMGGEVISALNiVTFPLEEDFAI--LKEILRGGNDKVSEAKASLTGGHS-IHDKTIKYGLSVT----GKVKKKEIRENNTPKDGDVILLTKKIG-TGLVTANFAQGLVSDEDFEActrQMATLNKYARDIFVKYQIHAATDITGFGLLGHLSEMA-GNDFTIILESAKVPVlSPAKKLAAEFL--------------------------------------------------------------------------
>UniRef50_Q3B0X6(29-252:331) Thiamine-monophosphate kinase n=11 Tax=Synechococcus RepID=Q3B0X6_SYNS9  E=2e-09 s/c=0.29 id=27% cov=32%
----------------------------------------------------------------------DVGWRAVAANLSDLAASGAISVdGITVALVAPGETPWSWVEGVYTGLRAALDAYGGVILGGD---CSKGSQRLLSITALG---RLGPLRLHRGDAKPGDILVTSGPhgLSRLGLAIL--------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8D417(89-359:731) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D417_DESK1  E=3e-09 s/c=0.24 id=21% cov=61%
---------------------------------------------------------------------------------------------------------------IVKGISDYGNRVGVPVVAGDT------WFDESFnkqplVNVACLGIVEKNKAV-LSKPRPGDLVVIignsTGRDGLLGSSFASAPLKDNMVEDIgavqIGDAlmeKMLIDVVNEVVEKKLVDYIKDLGGGGLTTAISEAAGDYDLGVEIYLDRLHLR---------MDLEPYeILASESqeRMLLAVPRENFNELIGILEKYEV--PYSVIGIFNDSGFIRV--YYKGRIIAEVPSKAMArPR--
>UniRef50_C7MDL0(60-198:372) Thiamine-monophosphate kinase n=1 Tax=Brachybacterium faecium DSM 4810 RepID=C7MDL0_BRAFD  E=3e-09 s/c=0.47 id=28% cov=38%
-----------------------------------------DAAVVSLPSPRLVATTDTLVEGFDFLPHTTtarwIGRKAAVQNLADVAAMGARPLALVSAISAPASTAPAVFEELTIGLTARAEAEGASLVGGD-----LGRADRLTVTVTALGSLPlEQAPVRRSGARAGDVLAI--------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8FH87(20-307:323) Selenide, water dikinase n=1 Tax=Desulfatibacillum alkenivorans AK-01 RepID=B8FH87_DESAA  E=3e-09 s/c=0.23 id=21% cov=52%
-------------------------------------------------------------------------------------------------------------------------EAGVALAGGHS-VDDKEFKYGLSVT----GVVHPSKILTNANVKKGDLLVLTKPIG-TGVLATAVKGQVDFqesESLLIEISGTLNRRAGEIMHTFEPHACTDVTGFGLAGHALEMSKGSNLSVTLFaheamfipkalelasmgllpagtyanrqfcENYTKVHPSVEQVQADLVFDPQTS---GGLLVSMTPAMARDYVSAM--NDQGLFAVIAGEV------------------------------
>UniRef50_A4E732(8-266:278) Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens ATCC 25986 RepID=A4E732_9ACTN  E=3e-09 s/c=0.25 id=23% cov=68%
-----------------------------------------------------------------------FGQIAAANSLSDIYAMGGRPSHAMNLLCIPSCLGIEVAGQILAGGADKCVEAGCSIAGGHTI-----NDDEPKYGLSVSGFVALDRMLANSGARVGDALLLTKAVGS-GIITTAIKGELIEQDEAAAVFDSMRTLNEApirLAEGLELHGCTDITGFGLIGHACEMAEGSGVQVELASGAVPLFDQVLDMArlgiipagsyrnqDFFGprvaadedlepgmLDALYdPQTSGGLLIAAPARDVDELARRLDAE--GRIAAVVGRVCE----------------------------
>UniRef50_Q72IH7(473-712:725) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Bacteria RepID=PURL_THET2  E=3e-09 s/c=0.27 id=24% cov=66%
-----------------------------------------------------------------------------------VSVVGAKPLAYTDGLNLgspetPEGY--HELAETIAGLKEASEALGVPVVSGNVslynesggKRIPPTAMVGV------VGVLEVDKRAEMGFRRPGEVLLLIGeERGELGASeVLYLLTGKEFGHPPRLDLGREKAVQEAIRDLIQrglTRTAHDVAEGGLLLALAEMTFPYGVGATVE-----VREE--------GLEALFGEAPSRVLFTVEKTRLQEATLLLEER--GLPYRVLGE-TGGKSLTVLTPGG---VLEWSLEELL----
>UniRef50_Q72IH7(74-321:725) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Bacteria RepID=PURL_THET2  E=3e-06 s/c=0.22 id=24% cov=53%
----------------------------------------------------------------------------VGGILRDIMSMGARPIALLDSLRFgppEEARSRYLLKGVVSGIAFYGNAIGVPTVGGDLYFHE-GYRENPLVNAMCLGLLREE-HLKRSRASLGRPIYYAGaKTGRDGIggAAFASRELKEEKAEDRPAVQVGDPFLGKLLMEATLEAIElDLVEGvqdmgaaGLTSSLSELAHKSGLGVELHLDLVPTREE----------------------------------------------------------------------------------
>UniRef50_A0QAT1(444-732:765) Phosphoribosylformylglycinamidine synthase 2 n=34 Tax=Bacteria RepID=PURL_MYCA1  E=6e-05 s/c=0.18 id=24% cov=68%
--------------SRAFITEQYDRYVrGNTVLAEHADGGVLRVDETT--GRGIAVSTDAsgrYTmLDPY---AG--AQLALAEAYRNVAVTGATPVAVTncLNFGSPEDPAVMWqFAQAVRGLADGCVALGIPVTGGNVSFYNQTGSAAIlptpVVGVLGVLDDVSRRLPTALGAEPGETLMLLGETRDEFDGSVWAQVTADHLGGLPPKVdlareKLLAEVLRAASRDGLVSAAHDLSEGGLAQAVVEaaLAGETGCRIVLPEDADP--------------------------------------------------------------------------------------
>UniRef50_A1RQQ2(96-345:693) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Thermoproteaceae RepID=PURL_PYRIL  E=4e-09 s/c=0.26 id=21% cov=58%
---------------------------------------------------------------------------------------------------------------------------GVPVVGGETWFDEDFTYTPIVLAT-CVGVVEAEA-VPKGYVEPGDYIVVAGLgadrsgLGGSAFASKTLEGGEDLGAIQVADPLMGKKLIDVVKEVsRCVKFIKDLGGGGLATALAELSHWFSLGVEFHLDKLHVRDA-SALPEEL----LISETQERLIFVISPRDLPCLEEALRKYEV--PYSIPGRFVKSDRVLV--MWKGVKIVDIP---------
>UniRef50_Q83FJ9(37-336:337) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Tropheryma whipplei RepID=Q83FJ9_TROWT  E=4e-09 s/c=0.22 id=24% cov=81%
--------GLGGFA--GLFDISFLKRYRSPLLVTSTDGVGTKVVIAQELDKH-----DT------------IGQDLVAMVVGDIAVVGGKPLFMTDYIACGELIP-ERIAQIVGGVARACQEIDCVLLGGETAehpeVMARNQYD---LAGAATGVVEASDLLGKDKVKTGDVLIGVASSGLHANGFSLVRKicrDVSF-AEYCPDLQTTWGealleptrmyvnLIRDLIKTGKLHAASHITGGGIPGNLPRILPE-GLGARLH--PWPIPDLFKVLCEFGSLSLSEVKNAwnlGIGLIIVASST-----SILEDIDDSWQARLIGEVIDGEAI------------------------
>UniRef50_D1BR39(32-340:343) Selenide, water dikinase n=3 Tax=Veillonella RepID=D1BR39_VEIPT   E=4e-09 s/c=0.21 id=24% cov=51%
------------------------------------------------------------------------GKIAAANALSDVYAMGGTP--LTAMNIV--GFPVPLVEQgvltdVLNGAGSIVAEAGAAIVGGHS-IENKEPIFGMSVT----GQVNPKQIWKNKGAQIGDVLVLTKRIG-TGIMNNALKAGLfpvGTEQAVTS-MSTLNRVAAEVAHNFTVHACTDVTGFSLMGHSVEMASASDVTIHIKAYDIPLFDDV---------------------------------------------------------------------------------
>UniRef50_B1HTV6(80-349:351) Phosphoribosylformylglycinamidine cyclo-ligase n=373 Tax=Bacteria RepID=PUR5_LYSSC  E=5e-09 s/c=0.24 id=24% cov=70%
--------------------------------------------------------------------------------VNDIVAQGAEPLYFLDYVALGKAEP-AKIEQIVKGVADGCVQSGAALIGGETAEMPGlYEEDEYDLAGFAVGACEKSAIVTGERIVEGDVLIGIASSGVHSNGyslvrkIVFADRQYAVDAIVENyeDLGPIgeallvptklyAKPVLAALKAADVHGCAHVTGGGFYENLPRMMPE-GLATEIDLGSWPVLrifEFLKDKGQLEDKDLYNVFNMGIgFVIAAPAAEADKVMAAVEAN--GEKAYTIGRVIKGNGVVFNGT-------------------
>UniRef50_B1ZT02(38-239:309) Thiamine-monophosphate kinase n=2 Tax=Opitutaceae RepID=B1ZT02_OPITP  E=5e-09 s/c=0.32 id=24% cov=28%
--------------------------------------------------------------------------------LSDLAAMGGRPTAAVLALTLDARVSRRWLEAFYRGLAACARLYRVPIVGGDIA-----QADGMVgASLTLLGEATGPRTLTRTGARLGDAIYVTGVLG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8UTM0(82-333:335) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8UTM0_9AQUI  E=5e-09 s/c=0.26 id=25% cov=67%
--------------------------------------------------------------------------------VNDVITTGADPL-LFLDYIATGRIDLQVLKAVIDGVVEGCKRGEVLLAGGETAEMPGFYPEGVYdLAGFCVGVCERGEVITGEGVRSGDVLLGLRSSGFHSNGFSLIRKVLKDKGVKLTDrveelgqsvgevlltpTRIYTPEVKLLKSNVELKALAHITGGGipenLIRVLPE-----GIRAVVDKKSIPENPVFAWIQKLGGVEEREMfrtFNMGVgMIAVVSPEDCDKALDAL-----GRDAFVCGHLEEGKREVV----------------------
>UniRef50_O67691(471-715:745) Phosphoribosylformylglycinamidine synthase 2 n=6 Tax=Aquificales RepID=PURL_AQUAE  E=5e-09 s/c=0.26 id=22% cov=46%
------------------------------------------------------------------------GKFVVAEVCRNLACVGAKPLAITDCLNFgnPERPEIMWqFVKAVEGMAEACEELGIPVVSGNVslynETVEKNEIRNVFPTpiVVGVGVLEKAEKYTPSKVEKESELYLVGNL----------EENLRLDGSeylkvihglIKGDVPPvdlekekiLINLLISFNNKELITCAHDVSVGGLLIALLEM------------------------------------------------------------------------------------------------------
>UniRef50_O67691(103-292:745) Phosphoribosylformylglycinamidine synthase 2 n=6 Tax=Aquificales RepID=PURL_AQUAE  E=7e-09 s/c=0.34 id=22% cov=52%
----------------------------------------------------------------------------VGGIIRDVLSMGARPIALADSLRFGE-FNYHETKRLVKGVVSGISFYgnciGVPTVAGET-VFEPSYKTNPLVNAFCLGVIPAGRMYRARATREGQLLFLigssTGRDGIFGAVMASGEFSEDVEEKRPNvqigDPYFGKKLVEAIMEIVEkdlIVGMQDLGAAGLAGSASEIAAKSEKGVELYLENVPLRE-----------------------------------------------------------------------------------
>UniRef50_A9B1J1(2-326:327) Selenide, water dikinase n=4 Tax=Chloroflexi RepID=A9B1J1_HERA2   E=6e-09 s/c=0.20 id=23% cov=67%
----------GAGALSNLISSLRLP--SSPQLLVGLDVSDDAAVYQLNQQQALVQTVDFFppiVDDPYSF-----GAIAAANALSDVYAMGGKPiLALAIA-----GFPRDLdpaiIQAIMQGGADKVAEAGAVLAGGHT-IIDNEPKYGLCVT----GLIDPALITRKAQAQPGDQLYLTKALGTGVISTASKRqiaDPADLAAAIESMLKLNRHAAEHIAMLGTIRSATDITGFGLLGHGLELARNSGVGLQINSRALPL-------------------------------------------------------------------------------------
>UniRef50_C0DBU4(5-194:200) Putative uncharacterized protein n=2 Tax=Clostridiales RepID=C0DBU4_9CLOT  E=6e-09 s/c=0.34 id=25% cov=54%
------------------------------------------------------------------------------------------------------------------------------------------------------GQGPRGFKRRDGEMRPGQDLIMAGYAGLDGACGIARARREELERRFCS--AFLKQLAGSPGPSPVIwageHLGADITayevlgEGGVLAALWNLSGVFNAGIEFDLRRIPIRQATVEICELYGLNPYRLRSGGGFMAAADNGG--RAVRALEAA--GIPAAVIGSVIPGTARRMSHGGESAGFLERPQPDEYDKIC
>UniRef50_D1YVN6(72-297:328) Putative thiamine-monophosphate kinase n=1 Tax=Methanocella paludicola SANAE RepID=D1YVN6_METPS  E=6e-09 s/c=0.28 id=20% cov=61%
--------------------------------------------------------------------------------VHDIAAMGGRPLGMVDVFS---SNSDEITQRVLKGMKAGIDKFGVPIVGGH--VHPDTPYAAL--DVAILGIAKKDTVIYSSTAKPGDDVVLAIDMdGRvHPSC------DLNWDTTFLKDASIVRQQVGSMVELAErkmLTAGKDVSNPGIIGTLGMLLEVSGVGADVDMSAMPKPES-------LEWEHWLKMYPGMgFIVTCKPENTEQVLDIYRNHKL--NATKVGKIV-----------------------------
>UniRef50_C8SBR6(35-291:311) Methanogenesis marker protein 2 n=1 Tax=Ferroglobus placidus DSM 10642 RepID=C8SBR6_FERPL  E=7e-09 s/c=0.25 id=22% cov=62%
--------------------------------------------------------------------------------VHDVYAMGGKPLA---ALNVVSARSKEEMEEIARGIRDACEKFDVKIVGGHI----HPDAKLPSIDVSMIGV--AKSILRSDTAETGDKIVFAADLeGKpH------PKLPYNFDSTNKSK-EVLKYQFESMVEIAERKlanAAKDVSNAGILGTIAMMMEVSGKGCEIFVDRIFKPKNVSFVQWLLS----YPACA----FVVTTKKEREVLEVFEKHNLA--AEVIGIVTDDKKVLLK---------------------
>UniRef50_Q055K0(3-276:299) Thiamine monophosphate kinase n=4 Tax=Leptospira RepID=Q055K0_LEPBL   E=7e-09 s/c=0.23 id=20% cov=64%
-------------------ESEIIRVLYPPGAAQTDDCYLDEEGRI--------FTTDTICEGTHFRTEWSgpkeIARKLVEVNVSDIAAGGGVPTkaFLNLGLSSQYS-KEEWIRPFSSSLQNALSFYNIELCGGDTYLSPS-----LNLTLTLIGVT--ARPWKRSGGKNGDFLYLTGSVGLSLLGYKLLNKSLDVPEPLRNLAleKHLTPkarlnVSKELSKRFPVSCCMDLT-DGLLQDLPKLAYSSKLGLKIDLEKIP--------------------------------------------------------------------------------------
>UniRef50_A9A265(16-336:340) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Thaumarchaeota RepID=A9A265_NITMS  E=1e-08 s/c=0.20 id=19% cov=88%
------------KQSQMAIGKLISSTHKLQKKAKIAHGFGHYAGIVEIPGGKLLAThTDGvgtkVVIANMMKKYNTIGIDCVAMNVNDIICIGATPISF-VDYIAANKNDVPIFKKIVEGLVKGAKKSAMPIVGGETAIMPdviEGKGFAFDLAGMVVGLVEKKQMVLGNKIRAGDVIIGANSTGIHSNGYSLARKALLKKYSVKDKVkgvgtigdALLKPteiytkPVLEMVEKCKINGLAHITGGSFTKLL----RLKKIGYEI--DSLPKIPPIMGLIAEQGVkseEMYKTFNMGVgFCVVAPKDQATKIKSIFKKYKISSQ--EIGQIVSKKGVFV----------------------
>UniRef50_B4CVD4(98-346:350) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Chthoniobacter flavus Ellin428 RepID=B4CVD4_9BACT  E=1e-08 s/c=0.25 id=21% cov=66%
--------------------------------------------------------------------------------VNDIAVVGARPLFF-LDYIGAERLDPPVFQQLIKGFAKACKEAGCALIGGETAQMPgmyqQGEYD---LAGTIVGVVDRKLALDGSRTKVGDVIIGLASNGLHtngyslARKVLFEKMGLHVDSMLPGVAKTLGDELLRVHKNYQpllaklpqgmIKGLAHITGGGLIDNLPRvLPKTTDAVIDTKTWKVPaIFEHIREGGSIDRTEMYQVFNMGIgMTVVVSAADREKALKLTKG-------KVIGRIEKGSGVV-----------------------
>UniRef50_P60819(6-334:349) Selenide, water dikinase n=13 Tax=Methanococcales RepID=SELD_METJA   E=1e-08 s/c=0.19 id=20% cov=70%
-EKIKLTelvklHGUACKLPSTELEFLVKGIVTDDDLLDKNILVGLgdDASIIKRNGLVIAKTVDVFTpiVDDPYIQ----GKIAACNSTSDIYAMGLLDIVGVLAIVgIPEKLPIHVVREMLKGFQDFCRENKTTIVGGHTILNP-----WPLIGGAVTGVGREEEVLTKAGVKVGDVLILTKPLGtQTAMALSRIPEEFKdlisiteeerdyiinkaIEIMTTSNRYALKALRKAEERVGDkiANALTDITGFGILGHSNEMAKNSNVLIEI--------------------------------------------------------------------------------------------
>UniRef50_B4WRX3(36-302:329) AIR synthase related protein, C-terminal domain n=1 Tax=Synechococcus sp. PCC 7335 RepID=B4WRX3_9SYNE  E=1e-08 s/c=0.24 id=24% cov=38%
----------------------------------------------------------------------------------------------------------EETQQIWAGMRAAATAYGVPIVGGHTNC--HSEYSGLAVAVLG----RASQLITSFEASPGDTLMMVinmagvyyGDYPFWNAATMAEPAMLR---------SHLSKLTD-LANANLCSAGKDISMGGLAGTLLMLCEASGCGALLDLNRVP--------------------------------------------------------------------------------------
>UniRef50_Q11IV2(450-706:744) Phosphoribosylformylglycinamidine synthase 2 n=111 Tax=Bacteria RepID=PURL_MESSB  E=1e-08 s/c=0.25 id=23% cov=47%
---------------------------------------------------------------------------------------GADPLAVTDNLNFgnpERPEIMGQFVRAIKGIGEACRALSFPIVSGNVSLYNEtlGQAIPPTPTIAGVGLIPDwSKMARIAFAGEGQAILLAGapeSWGTHlGQSAYLRDVHGRAEGAPPPvDLAHekrVGDFVRGVIRSGTVTAAHDCSDGGLAVALAEMAMASGIGARID-------------------------------------------------------------------------------------------
>UniRef50_Q1UZ94(5-236:319) Thiamine-phosphate kinase n=3 Tax=Candidatus Pelagibacter RepID=Q1UZ94_PELUB  E=1e-08 s/c=0.27 id=27% cov=49%
----------------ELIKNYFQKlSKKSPSALNLNDDVFFD------KKNKLAVSVDTYTEGNHFIdfkrPDLVIKKI-IRSSISDLICKGIKPKYY---FISGSGnkksFSKLNLSKISKSLNQEQNKYKIFLSGGDT-VFS----NKLSFTITSIGFADNIIYRNKAKLY--DDVYVSGNIGDSYLGLLVLKNKIKLNSRLK-------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0IE53(12-315:326) Thiamine-monophosphate kinase n=4 Tax=cellular organisms RepID=Q0IE53_SYNS3  E=1e-08 s/c=0.21 id=25% cov=67%
----------------QLLDRL--ARFAPP--GQLND----DTALLPPDSRALLVNTDVMVEGVHFSDAttapADVGWRAAVANLSDLAASGSEQVeGITVGLVAPGSTSWWWVEQVYEGISEALERFGGTLLGGD---CSTGNQRVLSISAFG---RLGPLRLHRALARPGDLLMSSGPhgLSRLGLALLqdtALPTPLSLPPMLKKQAirchQRPWPRFDALQTLMACKPEQLPWRaggtdssDGLLAAVESLCRSSGCGAVLRREALPRADD----------------------------------------------------------------------------------
>UniRef50_B5IK14(417-642:721) Selenide,water dikinase n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5IK14_9CHRO  E=2e-08 s/c=0.28 id=29% cov=45%
----------------------------------------------------------------------------------------------------------EVLHQTLAGIRSVLEAHGAPLLGGHT--LEARDGGGLVVTLSVNGSVERPQHWPKGPLRPGDALLLSRPLG-TGVLFaaamAAAAEPLWIDQALSQMQQSQASLVSLLRRH-GCTACTDVTGFGLLGHLGEMvaASPAGLRVELDAAAIPALP---GALELL--------------------------------------------------------------------------
>UniRef50_C7HVN7(28-331:339) Selenide, water dikinase n=1 Tax=Anaerococcus vaginalis ATCC 51170 RepID=C7HVN7_9FIRM  E=2e-08 s/c=0.21 id=21% cov=68%
------------------------------------------------------------VSDPYIF-----GQIAAANALSDIYAMGAEPI---CGLNIvlfPEDENINILKKILQGGASKVIEAGASLVGGHSIHDPKIKY-GLSVT----GKVDIDKVWKNNTPNEKDILILTKPLGvtlvtnAYGINILGQKE---MDKAISS-MIFLNKYAKEILEKYRISSATDVTGFSFMGHLSEM-LGDKYSAIIDSKNIPILDGAKKAAsefvftkggqrnrmhmenmveflvddfalEEVLYDPQTS---GGLLVSIHKDDAKDALEELRKN--NINAKIVGQISKK---------------------------
>UniRef50_D0L864(250-465:481) AIR synthase related protein n=1 Tax=Gordonia bronchialis DSM 43247 RepID=D0L864_GORB4  E=2e-08 s/c=0.29 id=25% cov=62%
--------------------------------------------------------------------------------INDLTAMGARPLGLLDAVGAP---TRSHLTRVVRGIAAAAQAWRTPVLGGHTQVGVHAS-----LSVTALGQTERPIPGGGGRV--GDTLSLITDLG------GSWRPGYQGRQWDSTSARSADELARMARLPAEVRpaAAKDVSMAGIAGTLGMLAEASGTGAELDVAAVP-RPDAARMGEWLTCFP------GYAMLMADR-------RSIEHTPAPTTARACGRLTSSPGVRLRWPDG-----------------
>UniRef50_Q6LH23(22-233:323) Hypothetical selenophosphate synthase n=2 Tax=Photobacterium profundum RepID=Q6LH23_PHOPR  E=2e-08 s/c=0.29 id=21% cov=52%
----------------------------------------------------------------------DFGAIAAANALSDVYAMGGQVTLAMNIFCVPVDLPQEVVGQILKGGADKVREAGAVLVGGHT--VED---DEPKFGLSVMGMIHPSKVQTKAAVESGDILVLTKPLG-TGVISTAAKRGKASQESIQTSTDSMKKLNRNAAQIFvkyPIKACTDITGYSLLGHALEMAEKSDVCMHFIADQVP--------------------------------------------------------------------------------------
>UniRef50_A7I447(118-371:378) Selenide, water dikinase n=3 Tax=Campylobacter RepID=A7I447_CAMHC   E=3e-08 s/c=0.24 id=25% cov=68%
------------------------------------------------------------------------GQIAAANSISDIFAMGAKPInALNIVGFDECNFGGEILSEILAGGKSKIKEAGAVLVGGHTIRSAET-----FYGLSVTGLVKGRDFWANNTAVAGDVLILTKPIG-TGIittAIKSKMIDFkDFEDAIESMISLNFKACEILRNY-EIHACTDVTGFGFLGHLSEMLNK-NISFEVSSQNFHYFKSVKK-CLEMGLIPggSYKNSEftskfcdkkppielcdaqtsGGLLAAVSENEVAKVLNHLQNE--GIDAFLVGFAVPKK--------------------------
>UniRef50_A6UX13(466-716:732) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Methanococcales RepID=PURL_META3  E=2e-07 s/c=0.24 id=23% cov=70%
----------------------------------------------------------------------------VCESVRNLATVGAKPIGMLDNLNFgnpEKPERFYQIKKCIEGLADGAEIIGVPVVGGNVSLYNETVIDGkdypinptPVISIVG---TIENINNIPKGAKEGDILIITAPTKDEmGGTeyykqIHNTEEGIVPKANLEVE-KEIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTNNIGVELDLGDY----NTNGLrNDIL----LFSESSGRIILSVDKNNADKVVKEL-------NGAIIGTV---KGNELKIKLNDNELINLPIEEM-----
>UniRef50_B5YF26(72-358:712) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Dictyoglomus RepID=B5YF26_DICT6  E=5e-08 s/c=0.21 id=20% cov=63%
----------------------------------------------------------------------------VGGIVRDILAIGARPIALLDSLRfgpIEKGRNKYLFEGVVGGISFYGNCIGVPVVGGEI-VFEDCYSSNPLVNVMCVGLLgPEQKSYRGKAEGKGNLLLLvgarTGRDGLQGASFASEKLDDEVHKKRPSvqvgDPFLGKLLIESCLEAAstdGVVGIQDLGAAGLVSSLSESARRGRSGVKVYLDKVPQREENMTAEEIL----LSESQE-RMLLVIRPEKAEEIISIFKK-------------------------------------------
>UniRef50_Q8TWZ2(66-273:301) Predicted enzyme related to selenophosphate synthetase n=1 Tax=Methanopyrus kandleri RepID=Q8TWZ2_METKA  E=5e-08 s/c=0.29 id=25% cov=57%
----------------------------------------------------------------------------------DVVVTGGEPI---VAFDAVQAESEEQAEEILEDLRKQAEGLGIKILGGNTQSHP----DLVpCVSVVVIGRLIADEPIPDGTAREGDALVFLGEPvrGDVGDRVYKAKVKF-------------NAFLRFLREGIDVSAAKDASRGGVLGNLLEMMGKAKKGVELRSMPYPTWTG-------------YL---GIFMVCMDPNDVERAAEI--AFEEGCPFTVAGEVVDEP--------------------------
>UniRef50_D1N977(85-342:347) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N977_9BACT  E=5e-08 s/c=0.24 id=21% cov=67%
--------------------------------------------------------------------------------IDDIAVQGAEPVYFMDYIGIGK-LRSPLYEEVLTGIADACKAANVAVLGGETAEMPGMYGNDFDLVGVITGIVEKSKMITGEKIRPGHVAIGFGSNGLHTNGFSLARKILfsQCSYNVRTYLDELGETVGEALLKPHtsyYPAIREAQERGLA--LDGIAHITGgglydnvprilpedVTAVFKTDVLPIPPIFKVLVEKGHVDPieaYRVFNMGVgMVWFVPANAADEAVEIGRSKGFTTG--IIGEIIPGH--------------------------
>UniRef50_C1A7Y1(17-298:323) Thiamine-monophosphate kinase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A7Y1_GEMAT  E=5e-08 s/c=0.22 id=24% cov=71%
------AMGAGGEFDTI---RMLMSRWGDLAADIGDDAAVLS----PITSGVRVVSTDACVEGVHFRREWiapyDVGVRAAAAALSDLAAMGAAAEYVLVAFVVPDGWRTA-LGAVADGIGAQVRRAGARIVGGN---LSRGAAFG--ITLTVIGT--AARAVSRAGAQVGDVVVVTGLLGGPGAALAAWESGVEPTGWAHERFVHPSPRlAEGALLAAAGASAMLDISDGLAADARHIAAASGVDLVIDDTRLPLGEGITA-------------------------------------------------------------------------------
>UniRef50_Q0W3P5(72-304:325) Putative thiamin-monophosphate kinase n=1 Tax=uncultured methanogenic archaeon RC-I RepID=Q0W3P5_UNCMA  E=6e-08 s/c=0.26 id=22% cov=57%
-------------------------------------------------------------------------------------------------------------EKVLKGMKAGVEKLGVPIVGGhihpDT---PYTAVD-----VAILGRVKKDSIIYSSTAKEGDDIVLGIDLdGRvHPSC------DMNWDSTFLKEAAIVRHQMESMVELGErhlLTAGKDVSNPGILGTLGMILEVSGAGAEVELDSIPKPAS-------LDWDRWLKMYPGMgFIVTCRPENTARVIEVFNNHKL--NASRIGKIV--PGSHLDIVRGGERA-------------
>UniRef50_A8M9Z8(69-300:315) Thiamine monophosphate kinase-like protein n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8M9Z8_CALMQ  E=6e-08 s/c=0.26 id=26% cov=65%
------------------------------------------------------------------------------GAASDLLVKFAKPIALVTSLTLRGDHTESELEELIKGINDAAKAIGASYIGGD---LNEGDDDVLDVALIGIAGKPIGRVP-----RLGDVLVTIPEFGFTGLIFKLWYS--GLLSNYINDSivvkgieltrrpKPWIPSGELGNRINCVNASMD-SSDGLGRVLYEM----GKGVRIRVYSLPVNKDVESTCRRYGLSveevVFNGGEEYLPVLAVKPE----CLDYFKALGFVDFA----KVEEGNGVYLDSR-------------------
>UniRef50_Q3ARU4(112-361:761) Phosphoribosylformylglycinamidine synthase 2 n=18 Tax=Bacteria RepID=PURL_CHLCH  E=6e-08 s/c=0.24 id=23% cov=55%
---------------------------------------------------------------------------------------------------------------------------GVPTVAGDI-YFEEGYTGNPLVNAMSVGIVEHHKTVSATAYGTGNPVLIvgssTGRDGIHGATFASEDLS-EASEEKRPSVQVGDPFAEKLLleatleaiETGYVVGLQDMGAAGITSSTSEMSargiEKYGVgGIEIDLDLVPIREAGMSAYEIM----LSESQE-RMLIVAAKGFEDKIIEVYQK--WDVQAVVIGEVTDDNHVRVK---------------------
>UniRef50_Q04EU4(58-311:328) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Lactobacillales RepID=Q04EU4_OENOB  E=6e-08 s/c=0.24 id=22% cov=69%
-----------------------------------------------------------------------IGQDLVAMVVNDLLAQGAKPLFM-LDYIGIDKVSSDKVAEIVSGIAKACRQSKMALIGGETAELPdmyfKDEYD---LAAFAVGVVEEDKILNGNRLQVGDTLLGIASNGLHSNGYSLVRNLLltrakktwsqlddSLQKELLRPTRIYAASLIPLLNNNKIHALSHITGGGlLENVPRMLSNQTAVEINWGSWPIPeIFQRLQETGKLSNHEMLETFNLGIgMVAAVSADESAEIMNQLKK--SGEKVYQIGKVVSR---------------------------
>UniRef50_C1SLQ6(14-318:325) Selenium donor protein n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SLQ6_9BACT  E=7e-08 s/c=0.20 id=22% cov=82%
--------------------KLFRPDQLLVGFETGDDAGVFDMG----NGLYLVQTVD--FITPVVDDAYDFGRISALNSMSDVYAMGGTPVTALSVLLYNCSIGGEIIKTMLQGAADEFAKAGCALAGGHT-VYDPEIKLGFSIT----GKITNGKIYKNVGLREGDILIYTKPLGI-GLISTALKAQMASPEDIKAVTDTMlmsNAAASEIMKKYDVSACTDVTGFSLAGHSYEMASGSGVTIEIDSRAtytiegafryakdfiIPAgaysnMEFLKGRCEfetkpdnahMVFFDPQTS---GGLLIGVSETDSNKLLGEL--LENGIPAQQIAYATAKK--------------------------
>UniRef50_A0LA23(95-342:353) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=cellular organisms RepID=PUR5_MAGSM  E=7e-08 s/c=0.24 id=25% cov=65%
-------------------------------------------------------------------------------SVNDLVVQGAEPLffldYFACGKLSPE-----TAATVVEGIATGCRAAGCALIGGETAEMPGFYTEGEYdLAGFAVGAVDKHKIIDGRHISPGDAIIGLASSGPHSNGYSLIRKlvlgqsGPGLEADFNGKplgevlLTPTHIYVLPLLELAKTHAIHGLvhiTGGGFWENIPRILPDA-TGALLKRSCWQ-QPEVFNLLQKLGNiaedEMLRTFNCGLgMLVIVPATQADSALAQLRAA--GEQAELVGEIT-----------------------------
>UniRef50_B3T9Z5(17-315:323) Putative AIR synthase related protein, C-terminal domain protein n=1 Tax=uncultured marine microorganism HF4000_APKG7N23 RepID=B3T9Z5_9ZZZZ  E=9e-08 s/c=0.20 id=22% cov=85%
------------KATEALIAQI--KSVGRKGDGEAIKLENGFAGLVKLGDGALAICTDG-VGSKLLLAGEldsihTVGIDCVAMNVNDLICVGAEPLSFVDYVALDK--PDEDLmGKIGMGLAEGCRRANCTLSGGETAILPE-LVHGFDIAGTSVGYVKQEDIIDGTKISEGDVLIGLKSSGPHSNGYTLIRKLFDGDKEIgKQLVEPTRIYVKEIMDLIKqvdVHGIAHITGGG----LDNIGRINDNFQYVIDNPLPVPsvfDWLQEKGEVEDSEMYRTFNMGMgMIVIVGEKNAEEAASIL-----GSDAQIIGSVRNGQGV------------------------
>UniRef50_D2L8W8(31-300:322) AIR synthase related protein n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L8W8_9DELT  E=1e-07 s/c=0.22 id=25% cov=48%
------------------------------------------------------------------------GRCAVLANINDIYAMGGRPLAMVDVV----GTPDEaTAREICRGMRDAAARYRVPVVGGH---LLRTAFDH-SASMAILGR--AKTCLTSFDARPGDSlVLATRPNG-------AWLGDLGFwNATLPEDDATLiahLELLPACAEAGLARAGKDVSMAGLAGTALMLAESSGVGCRLDVDAL---------------------------------------------------------------------------------------
>UniRef50_Q4FMQ1(82-189:342) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Candidatus Pelagibacter RepID=Q4FMQ1_PELUB  E=1e-07 s/c=0.56 id=24% cov=28%
-------------------------------------------------------------------------------SVNDLIVQGARPLlfldYISINKI-----DLNKLKLILKGIVRGCKISNCELVGGETAEMPgtyeKGKFD---IAGFAVGLVDEKKILSKKNIKKNDLVLAIPSSGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1U8X7(91-342:353) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Desulfovibrio aespoeensis Aspo-2 RepID=D1U8X7_9DELT  E=1e-07 s/c=0.24 id=27% cov=62%
-------------------------------------------------------------------------------SVNDVLVQGAAPLFFLDYFAtgkLESGVA----EQVVAGVCEGCRRSDCALLGGETAEMPGFYPDGEYdLSGFAVGMVDTPRLVTGTSVTPGDVLIGLGSSGAHSNGYSLIRKLFD-QSGLRPDqpfpgsdrtvaevliepTKIYVRAVLALLQTIGIKGMVHVTGGGfydnVPRVLPETTTA-----RIEFGSWPILPV---------FDWLKT--EGRLswpemlqifncgigyILICSPENAEKAMELLDARDD-VDAYRIGEITPRE--------------------------
>UniRef50_C0VYS5(29-349:381) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Actinomyces coleocanis DSM 15436 RepID=C0VYS5_9ACTO  E=1e-07 s/c=0.19 id=25% cov=86%
-----------GDRTVELMKAAVNASHNNTVLAGAGGFAGLIDASALVGMKRplLASSTDGVGTKVAIAQAMDihdtIGQDLVGMVVDDLVVMGAKPLlmtdYIATGKVVPEKIAD-----IVRGVAQACAMVDCPLIGGETAEHPGLMAEDEYdIAGAATGVVDEPNLLGAHRVQAGDVLIgmaASGLhsngyslvrriIADAGWEWDRHVDEFGrtLGEEVLEPTRLYTRDCLALIDAlpGQVHALSHITGGGLGANISRVIPQ-GLTAIVERDSWTIPP-VFDVMRRLGAVPWAALEEtlnlGVgMVAVVSAEGAAQAVSVLAAA--GMSAWVLGRVV-----------------------------
>UniRef50_A1VP32(45-313:341) AIR synthase related protein n=13 Tax=cellular organisms RepID=A1VP32_POLNA  E=1e-07 s/c=0.22 id=23% cov=62%
--------------------------------------------------------------------------------VSDIYAMGGRPIAVVDA-IWSQGAGTS--EQVMVGMAEASRRYGVPIVGGHT----NHRSDHGQLAVAILGR--ARKLLTSFDALPGHRLLMAidlrgayqepNPYWDASTSAPAERLRADLE------------LLPILAEDGLCNAAKDISMAGAVGTALMLLECSEVGAMIDIEAIPRPLGVPLLRWLQSFPSFG------FVLSVRPEVADEVVA--RFHARGIACADVGEVSAAPQVWLR---------------------
>UniRef50_B1XQD0(79-302:325) Phosphoribosylformylglycinamidine synthase II related protein, AIR synthase related protein n=1 Tax=Synechococcus sp. PCC 7002 RepID=B1XQD0_SYNP2  E=1e-07 s/c=0.27 id=21% cov=64%
----------------------------------------------------------------------------WCGVlvnVSDIYAMGGRPLAVVDALWA---CGDQQAQQIWAGMQAAAEKFQVPIVGGHTNTHSEYDALGVAI------LGRAKRLITSFDAQVGDRlVLVANFQGQ-------PRPQLPYcwDAATQADPAQLqaqWDLLPLLAERGLCSAGKDVSMGGIIGTTLMLLETSNCGAILDIGAVPCPPQ-------LDLQQWLLSfpSYG-FLLTVSPEQVSEV--EMLCEDQGLVAQAIATITPGHTLTLK---------------------
>UniRef50_C7LY34(9-296:309) Thiamine-monophosphate kinase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7LY34_ACIFD  E=2e-07 s/c=0.21 id=26% cov=84%
----------------EVIEAVIGA--GSASLAIGDDTATIaPSSKSRVWCSDLVV--DGVHVEVDRWPLAAIAHKAVAVNLSDLAAAGATPEATLLALACPPAIDARA---IAVAVAEAADRLGAPLVGGDTT---RGAT--LTLCVTALGQVD-GTPLTRRGARSGDHLLVTGPLGAASAglrRVLAGEAPEALPRHLHDALFAPQPRLAhgQLAASYGASAAID-VSDGFSLDLHRLADRSGVGFEL--DHVPIAPDATLA------DALGGGEDYELVIAIHDPSA--LIDACRAAGL-REPIVVGRIVADARQRT------------LGGEPLaPR--
>UniRef50_C2D8D1(7-333:361) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Bacteria RepID=C2D8D1_9ACTN  E=2e-07 s/c=0.18 id=23% cov=88%
MERILMSQNAysqagvdveAGYEAVSRIKKHVHATYRKEVLGDLGGFAGLfSLKDFHFDDPVLVSGTDGVGTKILLAKQLNrldtvgIDCVAMC--VNDVLAQGAEPLffldYISVGKNSPE-----RMEALVKGVCEGCKQAGAALIGGEMAEMPGlYESDEFDLAGFCVGIAERRALLHKSLVHEGDVLVGLASSGVHSNGFSLVRSILGQSlsqhPELLEPTKIYVKSVLPLVQQGLIHGISHITGGGFVENIPRM-LPSDLCAHIYDGSWE-KPAVFSMLQEQGnleyasmFEYFNMGI--GLVLSVGKSDAQKVMDALKTA--GEQVFVIGEVEE----------------------------
>UniRef50_C1SM36(53-343:345) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SM36_9BACT  E=2e-07 s/c=0.20 id=26% cov=67%
--------------------------------------------------------------------------------VNDIIVTGAKPLFF-LDYMATGKLSSEKMAQVVEGIAEGCRQAGSPLVGGETAEMP-GMYSGEDFDLAGfaVGILDKPKAVTGERISKGDVLVGLPSSGLHSNGYSLARklffEKLSMKPDdiLYDDVMLKHALLEPtriyvqqvlsvIEKGIDVKGMVHITGGGFYDniprILPE-----GAGVKINPDAFPTPGIYKFILEKSGIEEkelYRVFNMGIgYIMVLEHSEAEKCMS------LIDDACVIGNVTDTGIVEIEG--------------------
>UniRef50_C1F5Y2(111-376:785) Phosphoribosylformylglycinamidine synthase II n=3 Tax=Bacteria RepID=C1F5Y2_ACIC5  E=2e-07 s/c=0.22 id=22% cov=68%
----------------------------------------------------------------------------VGGILRDIFTMGARPLAVMDSLrfgpihseewvpqvrVSGPGLDTESeavlhknhsiLEGVVHGIAGYGNCFGVPNLGGETRFEPCYSGNPL-VNAFALGLVKRDEIFYAKATGVGNPVIYvgakTGRDGIHGATMASEEFKEGSEQK-RPNVQVGDPFMEKLLLEACIEAMRtgavvgiqDMGAAGLTSSSCEMGARGGVGIEMNLDDVPQRE-----TNMNAYELMLSESQERMLLVAEKGREQEVLDVF--TKWGLDGVVVGEVIAEPRMRI----------------------
>UniRef50_Q1QLI2(85-346:356) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=Bacteria RepID=PUR5_NITHX  E=2e-07 s/c=0.23 id=27% cov=68%
-------------------------------------------------------------------------------SVNDLVVQGAEPLFFLDYFACGK-LDPEVASAIVAGIAVGCREAGCALIGGETAEMPGLYKDGDYdLAGFAVGAAERGTLLPGRDIAAGDAVIGLASSGVHSNGYSLVRkivEASGLGFSVPAPFAPVTTLggalltptrlyvkscLRAIRETGAVKGLAHITGGGFTDNIPRVLPK-HLGIRIDLSRLTVLPVFKWLARQGGIAELELLrtfNCGVgMIAIVRRDAVEQVVDVL--TQAGERVAPLGSVIEASG-------------------------
>UniRef50_C7MPH9(9-230:321) Selenium donor protein n=2 Tax=Coriobacteriaceae RepID=C7MPH9_CRYCD   E=2e-07 s/c=0.27 id=26% cov=30%
------------------------------------------------------------------------------------------------------------------------------------------------------GVVHPDHIIRNGGARPGDVLFYTKKI---GTGILTSAFRAKLETD-ESMREAINSMME--LNKYGAAAMRrvrthaatDVTGFGLAGHLHEMLEASGCAARLQWDALPLFDKV---------------------------------------------------------------------------------
>UniRef50_B1L603(25-289:290) Hydrogenase maturation factor-like protein n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L603_KORCO  E=2e-07 s/c=0.22 id=23% cov=60%
-------------------------------------------------------------------PPSDIGSISFHLPASKISALGADPKFAFGSFFIPEGH-----RGVVEDFEREARRYGSR--TG-SKIV-RGRRALAIVSMRG----EAREIILPTNVKIGDYIALIGVPGAEFLYLISNKkpelfKRLGMEDSIWRWKRALWMLtcidaVRTLLTISRVNGLLCVDSRGILESLNKLADISGTGFIISRNRIIFPPELMRIATQMDLDPLELPSSGVTLAAIPK-------------------------------------------------------
>UniRef50_A8G794(47-338:347) Phosphoribosylformylglycinamidine cyclo-ligase n=10 Tax=Prochlorococcus marinus RepID=PUR5_PROM2  E=2e-07 s/c=0.20 id=19% cov=29%
--------------------------------------------------------------------------------INDIITSGAKPLFF-LDYIATGKLDKKQLLRVVQGISHGCGENNCSLLGGETAEMPgfysKNKYD---LAGFCVGIVDEDKLINGKKVSENDLIIALKSNGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P49903(53-371:392) Selenide, water dikinase 1 n=64 Tax=Metazoa RepID=SPS1_HUMAN   E=2e-07 s/c=0.18 id=22% cov=85%
-------------------DEQFLGAVM-PRLGIGMDTCVIP---LRHGGLSLVQTTDyiyPIVDDPYM-----MGRIACANVLSDLYAMGVTECDNMLMLLgVSNKMTDRERDKvmplIIQGFKDAAEEAGTSVTGGQTVLNP-----WIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVavhqwldipekwnkIKLVVTQEDVElayQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVlakMAAVSKACgNMFGL--MHGTCpetSGGLLICLPREQAARFCAEIKSPKYGEghQAWIIGIVEKGNR--------TARIIDKPR--------
>UniRef50_A8A901(14-276:282) AIR synthase related protein domain protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8A901_IGNH4  E=2e-07 s/c=0.22 id=26% cov=70%
---------------------------------------------------RLVFNVDGFSAKGVlleFMDLRDVGWRGVTACVSDLVAKLVKPKYFLHSVY---GSDVEEVREIVEGIVEAAEEYGLAFLGADT---NKGEA---AVDVFCFGLSDLD-PPRLGGARPGDKVVV--PEGCWGCINRCLR------GEYWEHCKRPKVPLELLERLRGyekyVHASTD-SSDGLVISLYKLAWASGVTIALHEPP-PGPLGEEGLYGGEEYLP---------VFVVDPSASEAVEEAVKGR-------AIGEVLPgRPEVVYKG-----RTLDP----------
>UniRef50_C8W995(21-338:352) Selenide, water dikinase n=3 Tax=Bacteria RepID=C8W995_ATOPD   E=3e-07 s/c=0.19 id=20% cov=84%
----------GAGELAKLLSDI--KVHEDPNLLVGFDKADDAAVYKVTDEIALVETID-------FFPPIaddpyTYGAIAATNALSDVYAMGGEPKVALNVMAVPEDMSSHVVYEILRGGYDKVYEAGANIVGGHS-IYDNEPKYGLAVS----GFVNPKKMYTNSGARADDVLILTKALGVGVLTTAAKADMLSIEEMSVAEASmmTLNRYARDIMVNYDVHAVTDVTGFSLMGHLLEMCQGSGLLAKITVNNIKFLSTRVFELARLGILPAgmyrnrhyaekYVQAEGVsremsdvlfcpetsggLLISVAHDDAQHLLAALQANEHTANSCVVGY-------------------------------
>UniRef50_UPI0001C31B45(11-282:326) thiamine-monophosphate kinase n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C31B45  E=3e-07 s/c=0.22 id=23% cov=58%
----------------------------------------------------------------------DVGHRALAGALSDVAAMGAEAGEAYLALVLPPGLDDAALRELFAAAQQLAAATGTTIAGGD---LARGPALVASVTVVGWADAEHEL-IGRDGARPGDLVGVTGALGGSGAGLELLEGRVG-PARLDPDVAralirrhlrPQPRIAEGRALAAAGARAMIDISDGIATDAGHIARRSGGRLVLALDRLPLADGVAEVAAALGQPPAALA------------------------------------------------------------------
>UniRef50_B9LT08(71-355:759) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Halobacteriaceae RepID=PURL_HALLT  E=3e-07 s/c=0.21 id=24% cov=68%
----------------------------------------------------------------------------VGGIVRDTMSMGAYPIALLDSLYF-GGFDRErsryLFEGVVEGISHYGNCIGVPTVGGSVAFHD-GYEGNPLVNVACVGLTNEDRLVTATAQEPGNTLMLvgngTGRDGLGGASFASEDLAEDAETEdrpavQVGDPYAEKRLIecnEALVDEDLVLSARDLGAAGLGGASSELVAKGGLGARLDLDSVHQREPNMNAMEIL----LAESQE-RMCYEVAPEDVARVEALAERFDLG--CSVIGEVTDGNYV------------------------
>UniRef50_B9L5P2(44-345:347) Selenide, water dikinase n=15 Tax=Bacteria RepID=B9L5P2_NAUPA   E=3e-07 s/c=0.19 id=25% cov=46%
------------------------------------------------------------------------------------------------------------------------------------------------------GVVNPKQMIRNNTLKKDDVIILTKPL---GMGILTT----AIKADLVSDevasevaeiLRTLNYKASIIAREIGVSAMTDVTGFGLLGHLYEMSGK-KFTIEVEFDKVPfISEAINQAS--MGIIPagsynnqifvekyvefvrnlsfeeqmilFDAQTSGGLLISLPQEKAEEYLK--RAGNEGVFAKIIGNVKEKEEKFIK---------------------
>UniRef50_A3YWY9(438-630:711) Putative uncharacterized protein n=1 Tax=Synechococcus sp. WH 5701 RepID=A3YWY9_9SYNE  E=5e-07 s/c=0.30 id=31% cov=40%
--------------------------------------------------------------------------------------------------------------------------LGARLVGGHT-LEQRTTSEGLSLALSVTGRSEPGRFWAKGDLAAGDRLLLSRPIGSgvlFAGAMAGAAEPEWIDGALEVMAQSQQPLVE-LLAAHGCRACTDVTGFGLLGHLGEMleAAAEPLRVVLEPQALP---AFSGALELL--------------------------------------------------------------------------
>UniRef50_B7H4T6(116-359:739) Phosphoribosylformylglycinamidine synthase 2 n=87 Tax=Bacteria RepID=PURL_BACC4  E=5e-07 s/c=0.24 id=23% cov=68%
----------------------------------------------------------------------------VGGIIRDVFSMGARPVALLNSLRFGELQSPRvkyLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPL-VNAMCVGLINHEDIKKGQAHGAGNTVMYvgasTGRDGIHGATFASEELSESSEAKRPAvqvgDPFMEKLLIEACLELIQSDALvgiQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRET--------GMTPYEMMlseSQERMLIVVKKGREQEIVDLF--EKYGLAAVTMGKVTEDKMLRL----------------------
>UniRef50_B7H4T6(445-713:739) Phosphoribosylformylglycinamidine synthase 2 n=87 Tax=Bacteria RepID=PURL_BACC4  E=5e-06 s/c=0.20 id=24% cov=65%
------------------------------------------------------------------------GKIAVAEAARNIVCSGGEPLAITDCLNFgnPEKPEIFWqIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYpTPTVGmVGLVHDLKHVTTQEFKqAGDLVYVIGETKAefggselqkmiHG-KIFGQSPSIDLDVELKRQKQVLEAIQAGL-----VQSAHDVAEGGLAVAISESAIGAkGLG-----ATVKLDGEATAA--------LFAESQSRFVITVKRENKE-------AFEKAVEAIQVGEVTSTNEVTIHNE-------------------
>UniRef50_Q1H4W1(54-345:346) Phosphoribosylformylglycinamidine cyclo-ligase n=71 Tax=Bacteria RepID=PUR5_METFK  E=7e-07 s/c=0.20 id=25% cov=65%
-------------------------------------------------------------------------------SVNDILVQGAEPLFFLDYFACGK-LDVDTAAQVVQGIAAGCEQSGCALVGGETAEMpgmyPAGEYD---LAGFVVGAADKDALIDGSTIAEGDVVLGLASNGAHSNGYSLVRKLIDLSGvDLESDFYgrPFRDVVMAptriyvkpilkLLQAIKVKGMAHITGGGITEnvprVLPE-----GLTAEVRQGSWEIPPLfswLQEQGNITDQEMYRTFNCGIgMVVIVSAQDVAAAKALLSAE--GEQVWEIGRI------------------------------
>UniRef50_A4EBR4(94-362:367) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Bacteria RepID=A4EBR4_9ACTN  E=7e-07 s/c=0.21 id=25% cov=68%
--------------------------------------------------------------------------------VNDILASGAEPLFF-LDYVAIGHIEAEHMAKIIKGVADGCKLAGCALVGGemaeHPGVMAPADYD---LAGFTVGVVDRPKMLDPANVRPGDVILGLPSTGVHSNGYSLVRKVIGVDGikpgtpeaaaKAEELSRPLeelggasladalltptriyvKPILELLRGGAPVHAIAHITGGGITENLNR-ALADDVDAVVTRngaemgwDVPPVITYVSRQAELAPNEACKTFNMGVgLCLIVAPEDEAAVTEALVA--LGEKPFRVGECVEGSGKVV----------------------
>UniRef50_Q8UEB0(469-750:775) Phosphoribosylformylglycinamidine synthase 2 n=86 Tax=Bacteria RepID=PURL_AGRT5  E=7e-07 s/c=0.20 id=27% cov=27%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVHDCSSGGLALAVAEMAISSGIGATI--------DAVEGHNPILTF---YGEDQARYVLTVKKSDLDKVRAAAKAA--GVSCPLIGT---TGGSTVK--LGTARAVE-----------
>UniRef50_C9M8L2(77-330:332) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Synergistaceae RepID=C9M8L2_9BACT  E=8e-07 s/c=0.22 id=21% cov=67%
--------------------------------------------------------------------------------VNDLVTGGARPLFF-LDYIACGALNEPVFAPVVESVARACASCGCALLGGETAEMPGVYGPQTFdLAGFAVGVVDERDVIDGSSVQEGDLLVGLHSSGVHSNGYTLVREALA-QSIAKGDLsrpgpvpgetlgQSLMKPTRLYVNqalsaarTGAVKAMAHITGGGMAGNVNRVLPAGLVcDVDFSSWKRPAVFDLIASCGVAEDEMRRVFNLGIgFVMITSPDSLGRLTDALKAA--GENPQVIGRVV-----------------------------
>UniRef50_Q8XIK1(12-243:246) Selenophosphate synthetase n=1 Tax=Clostridium perfringens RepID=Q8XIK1_CLOPE  E=8e-07 s/c=0.25 id=21% cov=58%
-------------------------------------------------------------------------------------------------------LNMNILGEILRGGADKVLEAGAVIVGGHT-VQDDEPKYGLSVT----GIVHPDKVLKNYGSETGDILILTKPIGL-GIintAIKAKIASKEAYEKAVKVMAYLNKYAGEIITDYNITSCTDITGFSLIGHAYEMAEPSKKTFRIFKDAIPFIKEAKEYASM-GLIPAgcyenkrylegkYLLNnveswmedilfdpqtSGGLLISCKEKDYIDILTRL--EKLEVESAVIGRV------------------------------
>UniRef50_UPI0001BC434D(68-352:359) phosphoribosylaminoimidazole synthetase n=3 Tax=Fusobacterium RepID=UPI0001BC434D  E=9e-07 s/c=0.20 id=27% cov=63%
---------------------------------------------------------------------------AVAMCVNDVLCHGAKPLffldYLACG-----KLDSQVAAELVSGVTEGCLQAGAALIGGETAEMPGfyqvGDYD---IAGFCVGIVEKENLIDGRKVKEGDKIIALASSGVHSNGFSLVRKIFTDYDEViqtkehgrgkVSDIL-LTPTriyvknILKVLEKFQVNGMAHITGGGLPENLprcmgKEFSpivwKEKVRTLEIFEllqERGEISEE-----EMYGT--FNMGIGYTLV--VNAEDSEAIIDYL--NSLGEKAYEIGYI------------------------------
>UniRef50_Q9UX29(20-179:323) Phosphoribosylformylglycinamidine cyclo-ligase n=12 Tax=Sulfolobaceae RepID=PUR5_SULSO  E=1e-06 s/c=0.36 id=18% cov=34%
---------------HNMISQIISSTYKNTIIGAGHYSGVIKIGSLNIAMHTDGVGTKTFlalqtrIIKPV-----GIDCVAMN--VNDLICVGAKPVALVDYIALERPM-DNVVNEIIDGIVQGAKEADVEVIGGETAIMP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7X0W1(63-374:729) Phosphoribosylformylglycinamidine synthase 2 n=61 Tax=Staphylococcus RepID=PURL_STAA1  E=1e-06 s/c=0.18 id=29% cov=28%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLTSSSSEMAAKGGSGLHLRLEQVPTREP--------GISPYEMMlSETqeRMLLVVEKGNEQKFLDLFDKHEL--DSAVIGEVTDTNRFVL--TYDDEVYADIPV-EPL----
>UniRef50_Q3ZZB9(293-555:953) Phosphoribosylformylglycinamidine synthase II n=7 Tax=Bacteria RepID=Q3ZZB9_DEHSC  E=1e-06 s/c=0.22 id=25% cov=45%
-----------------------------------------------------------------------------------------------------------------------------------------------------IGLIPKKYALPGKQ-SAGDLVVLiggrTGRDGIHGVTFASgelndRSTELSFTAVQIGNAIVEKRMLDTLLQARDrelfVRIT-DCGGGGLSSAVGEMAESTGVKIYL--DKVPLKYSGLTYSEI-----WISESQERMLLAVNKEKLGEILALFESE--GVEASVIGEFTSD---------------------------
>UniRef50_Q7UI59(52-355:359) Phosphoribosylformylglycinamidine cyclo-ligase n=6 Tax=Planctomycetaceae RepID=PUR5_RHOBA  E=1e-06 s/c=0.19 id=21% cov=66%
--------------------------------------------------------------------------------VNDLICTGAEPLFFLDYVAM--GRDDpARLERIVQGISDGCVDGDLALLGGETAIMPDMyGTDDYDLAGFAVGVVERKRLVDGHLIAPGDVVLglqASGLhsngfslvrkiIADHGHQWSDVIDELNQDTKTPETLAQVCLRPTKIY-VSAIRSIQSHYR--VKQVLHGIAHITGGGIEENLDRI-LPPGVNAE-----IDPnaWTpnpifqwlqqtgdvatsemrrVFNMGIGMAVVVNEYYAASVAS-QVAKAGIECSPIGRIVEGSSKVV----------------------
>UniRef50_UPI0001C30E92(485-736:752) phosphoribosylformylglycinamidine synthase II n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C30E92  E=2e-06 s/c=0.22 id=28% cov=63%
-----------------------------------------------------------------------------------LACVGAEPLGLTncLNFGNPEKPHIAWqLTESVRGMADACRALDTPVVGGNVSLYNEGGGGPIYPTpvVGIVGRLPDAARAGRlGFAHAGDAIAVV----RAASPSLAASELAKLRGEALPDGLPerslpaLRAAIELVRDAvrrGDLRSAHDVAEGGLAVALAESALAGGNGARVD------LALVGGAtCQSLPLDEqLFGEGPGTFVLSGPRAALDALAAA---APEGVAVSVVGEV------------------------------
>UniRef50_B7G902(437-651:791) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G902_PHATR  E=1e-06 s/c=0.26 id=24% cov=27%
-----------------------------------DDAAV--QILPNKAGGAIVQTIDYFreiVKDPFTF--GKI--VAVHA-LSDIHAMGATPQtAMTLAvapFAADEEVTESTLLHLLSGVSDILQDENVQLVGGHT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8FAM7(423-716:743) Phosphoribosylformylglycinamidine synthase 2 n=93 Tax=Firmicutes RepID=PURL_BACP2  E=2e-06 s/c=0.19 id=22% cov=76%
-----------------------------------------DAGVLRIRGTKkaLAMTTDCNARYLYLDPEVG-GKIAVAEAARNIVCSGARPLAVTDNLNFgnPEKPEIFWqIEKSADGISEACRTLSTPVIGGNVSLYNESNGTAIYPTPVIgmVGLVEDTAHITTKSFqQAGDVIFVIGETKEEFAgselqkmtegRIYGKAPEIDLDVELARQEALLAAIQNGL-----VQSAHDVSEGGLGVALAESTFGTdGLGADIQ---IDLDSEASLFSETQS----------RFVVTVKPEHREAFAAAVK------DAKEVGTVTNDGVFTVKNQEG-----------------
>UniRef50_A8FAM7(116-359:743) Phosphoribosylformylglycinamidine synthase 2 n=93 Tax=Firmicutes RepID=PURL_BACP2  E=2e-05 s/c=0.22 id=23% cov=68%
----------------------------------------------------------------------------VGGIIRDVFSMGARPIAVLNSLRFGELTSPRvkyLFEEVVAGIAGYGNCIGIPTVGGEVHFDQSYEGNPL-VNAMCVGLINHEDIKKGQAKGVGNTVMYvgakTGRDGIHGATFASEEFSDESEEK-RSAVQVGDPFMEKLLLEACLEVIKnDALVGiqdmgaaGLTSSSAEMASKAGSGIEMNLDLIPQRETGMSAYEMM----LSESQE-RMLLVIEKGREQEIIDIFEKYDL--EAVSVGHVTDDKMLRL----------------------
>UniRef50_A8A9K5(70-352:416) AIR synthase related protein domain protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8A9K5_IGNH4  E=2e-06 s/c=0.20 id=25% cov=81%
--------GEGGVGSRGLGDWAVHEALTS--LSGGGDAARV---------GDLVLAVDGFhsrlSSVPLL-----MGFHAVRAAVRDVMVSGGAPVASLIDVHVADDTDVAYLLDVTAGAYVAGELTGAPLVGGSTLRIGGDAVIGNRVTGGAFAVGRKVRDWSRFNASPGDELYAT--VGKGGGTVTAyalthgrpELVKLTLNVDFVYD-------IKRAMEVECVKGAFDWTNGGIALDAFEISRKLGVKVVLWKSVYeAVHPELLKAFEEDGIDPLRTSVD-SVVFVAERGCELPFVK-------------VGEVEAGEGVYLEGE-------------------
>UniRef50_B2GKA9(55-273:345) Selenide, water dikinase n=19 Tax=Actinomycetales RepID=B2GKA9_KOCRD  E=2e-06 s/c=0.26 id=24% cov=62%
------------------------------GLDDGDDAA----AVLVRPDLAVVSTADFFT--PVVDSAHDWGRIAAANALSDVYAMGGTPV---VAINLvgwpRELLPMELMSEVLQGGLDVAAQAGCPVIGGHSIDAPE--------PTYGMavtGTADPQRLLRNDAARPGLPITLTKPI---GVGLLNNRHKATgevFPAAIETMTA-LNRDASRAALAAGVEAATDVTGFGLLGHLYKMCRASGVGATIDAAAVPL---VEGAADAL--------------------------------------------------------------------------
>UniRef50_D2NR50(119-241:414) Phosphoribosylaminoimidazole synthetase n=1 Tax=Rothia mucilaginosa DY-18 RepID=D2NR50_9MICC  E=2e-06 s/c=0.45 id=26% cov=29%
-------------------------------------------------------------------------------VVDDIVVCGAKPLFMTDyiatGKVVPERIAD-----IVRGIAGACAQAGTALVGGETAEHPGLLAEDEYdVAGAATGLVEADELLGPDRVREGDVLIAMASSGIH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q8TX80(44-327:327) Selenophosphate synthetase n=1 Tax=Methanopyrus kandleri RepID=Q8TX80_METKA  E=2e-06 s/c=0.20 id=22% cov=69%
--------------------------------------------------------------------------------VNDVLAMGGRPVGLVNVLSTS---DVDVCREILEGMREGAWKFSTPVLGGHT----HPDTPYTAVDAAIVGVTDEEHLVLSSTAEEGDLIV--------FVIDLNGRpypeYPLNWDTTTMKDPDYLRRQMEAVVEASKlVKAGKDVSNPGLVGTLAMMLEASGcLGAEVWLDSIPKPEDVDMVT------WLKMYPGMGFVYAVDSERDVRAIRRVLSDAR-LEVSVIGEVTEDGVVKVSEGDESARVFDFREDRILgvsPR--
>UniRef50_Q18CW2(81-352:358) Phosphoribosylformylglycinamidine cyclo-ligase n=8 Tax=Clostridiales RepID=Q18CW2_CLOD6  E=3e-06 s/c=0.20 id=22% cov=28%
--------------------------------------------------------------------------------VNDLICQGAKPLffldYIALGKLVPE-----HIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYdLAGFSVGIADKEKIVSGNNVKSGDVLVGISSSGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q01XD1(11-221:306) Selenophosphate synthase n=3 Tax=Bacteria RepID=Q01XD1_SOLUE   E=3e-06 s/c=0.26 id=22% cov=51%
------------------------------------------------------------------------GAIAAANSLSDVYAMGGRPISALSILAYPAKGDMDDLAAILKGGAEKMHEASCSILGGHSVNDEEVKFGYSVT-----GTVHPARVKANAGARAGDALVFTKRLG-TGVIGTALKRGIARDEDVAEATASMLTLnrtaCEEMLSY-DVGGCTDVTGFGLIGHAREMAIASGVTLEIESDAL---------------------------------------------------------------------------------------
>UniRef50_A6QAK6(455-707:740) Phosphoribosylformylglycinamidine synthase 2 n=33 Tax=Epsilonproteobacteria RepID=PURL_SULNB  E=3e-06 s/c=0.22 id=20% cov=61%
-----------------------------------------------------------------------------------VAMSGARPLSITDCLNYgnPENPEVMWqFAQGCEGIKEACLELNTPVVSGNVSLYNETNGVSVFPTPAIamVGLNDDQNKVLPSVFQhEGNNIVLIGETkGEFGGSLYIKElfgetvgtlPSFDYKTELK-----LWELVIEANKIGLLESAKDVNVGGIAIALSKMAAVSSKGIT-------VKASVSNSRDIFD------ESQSRALLEVADADLEELLDM--AAGLGLKAEVIGKI------------------------------
>UniRef50_B8LBF8(1-166:176) Thiamine-phosphate kinase (Fragment) n=1 Tax=Stenotrophomonas sp. SKA14 RepID=B8LBF8_9GAMM  E=4e-06 s/c=0.33 id=25% cov=46%
----------------------------------------------------------------------------------------------------------------------------------------------------------------RDRAQVGDDLWVSGTLGDAAGALKLWQQGAlnVAAATLLADYEHLrlrllrpTPRVTLGLRLRAFAHAAVDVSDGLLADAGHIAARSGVAVHVDADMLPISPELR---ELLGREearecALRGGDDYELCFTAAADQRDALMYL--SQTLDLPLTRIGRIAEGQGVQVDGE-------------------
>UniRef50_D1ATX5(102-362:363) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Anaplasma centrale str. Israel RepID=D1ATX5_ANACI  E=4e-06 s/c=0.21 id=26% cov=65%
--------------------------------------------------------------------------------VNDILAQGATPLFFLDYFST-GSLDYDTTLEVISGIAEGCRRADTALVGGETAEMPGMYPAGCYdLAGFAVGIVEKsEILPRTDQVRTGDVIIGLASSGLHSNGFSLVRKVLQ-DRNIAYDSpYPLADGVTwagilleptriyvrpVLQVSQMIKAAAHITGGGLVhnipRVLPEslaaniqlgtWKQHSIFSWLEREAQIPATEMSETFNCGIG-----------MVLIASEDAAGRVLQVL--GESGEDAYVIGSVVlrERHSVIL----------------------
>UniRef50_A7GYY9(65-352:729) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Proteobacteria RepID=PURL_CAMC5  E=5e-06 s/c=0.19 id=22% cov=24%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLTSSSFEMAGRSGSGMKMQLDRVPMREE--------GMSPYELMlseSQERMLICAKKGCEQKVLEIFKKWDL--DAEVIGEVTDSGQMQL----------------------
>UniRef50_UPI0001C369C7(80-181:187) hydrogenase expression/formation protein HypE n=1 Tax=Clostridium hathewayi DSM 13479 RepID=UPI0001C369C7  E=5e-06 s/c=0.54 id=31% cov=31%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGGILSALWNLSGAYMTGIEFSLRQIPVKQETIEVCERYNLNPYRLYSDGCLLF-VTDNGGEMVLSL---EREGIHAAVIGRVTEGIGRIIRHGESTG-YLDRPAED------
>UniRef50_C3XH11(497-688:798) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XH11_9HELI  E=5e-06 s/c=0.29 id=18% cov=52%
-----------------------------------------------------------------------IGaKIAVAQAGRDVALSGAKPLAITdcLNFGSPENPEVMWqFRETCEGIKEACKALQTPVVSGNVSLYNQTNDEAIYPTPSIvsVGLLEDSNKAIGSHFVSKDSYIcmlgvmdnslqLSGSILQ--KVIGAKNSGILHDINLESELK-LWEILNQSIANEYILSAKDIAQGGLAITLCKMAILGKTSVEVLTDKI---------------------------------------------------------------------------------------
>UniRef50_C8W0C8(302-553:962) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Clostridia RepID=C8W0C8_DESAS  E=5e-06 s/c=0.22 id=25% cov=41%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------QAGDVALVlggrTGRDGIHGATFSSA-EMTDMTITVNSSAVQIGHAIEEKRTSDAileasqeglIRAITDCGAGGYGSALGEMGEKIGVKVFL--DRVPLKYP--------GLNPWEIwlsESQERMVLAVAPENMDRVMAICR--NYNVEATAIAEFTGDGRLLV----------------------
>UniRef50_Q979X9(2-202:221) Thiamine monophosphate kinase n=2 Tax=Thermoplasma volcanium RepID=Q979X9_THEVO  E=5e-06 s/c=0.27 id=17% cov=58%
---------------------------------------------------------------------------------------------------------------------KVLKMYDVDFIGGDLK-----EGMDLILTGIAIGKQKKTLTRKRSDIGRKQMVAYTNKLGRAASGYIFYKSGYD-SVEGINMMLGITPRLEEARIISeyGAKFMMDL-SDGLYSSLNQMKADYGVGFKIVEDEVVYDDSARKAAEISGASVYDIACgyggDYELLFTVPEENYRDFAQAMESN--NIEVHFIGETWEGENIVFDGKTWTK---------------
>UniRef50_A9A5G5(100-364:721) Phosphoribosylformylglycinamidine synthase II n=4 Tax=Thaumarchaeota RepID=A9A5G5_NITMS  E=6e-06 s/c=0.21 id=23% cov=48%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------NHAKKGDiVVLMGGSTGRDGIG-GSQFASDSLESEDRSAVQIPDPFIEKLiieaileaRNDKLIHAMKDLGGGGLSCAISETADALEIGIEMDVDKVHTRES--------GMHPdeiMVSESQERMLIVTSKTKFKKLQAICKKFRIG--CSVIGTVKSDNQMHVKKgkktfanlptdVVANATLLDLPSKEP-----
>UniRef50_C7MMK4(78-375:411) Phosphoribosylformylglycinamidine cyclo-ligase n=7 Tax=Coriobacteriaceae RepID=C7MMK4_CRYCD  E=6e-06 s/c=0.18 id=26% cov=68%
--------------------------------------------------------------------------------VNDILATGAEPLFF-LDYIAVGKLKSEAVAEIVGGIAEGCRQAGCALIGGemaeHPGVMDPEEYD---LSGFSVGVVDRARMLDPENVTEGDVLLGLASSGLHSngyslarKVCLEGRTHYEVrlpqsllggesvqDALLEPTRIYVKSVHTALTNHPhAVHALAHITGGGITENLNR-ALPSHLDAQVDIGSwtmKPIIPFVCRAAKLSESEALKTFNMGLgLVLIVDAAAVDSVEHTLQ--EAGEEVFRVGHVVAGSGAV-----------------------
>UniRef50_B2UNI3(82-329:333) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Verrucomicrobiaceae RepID=B2UNI3_AKKM8  E=7e-06 s/c=0.22 id=24% cov=66%
--------------------------------------------------------------------------------VNDILTTGGDPLlfldYLGIS-NLER--ERSRITRLVAGMCDYLESCNCILAGGETAEMP-GVVPESIVELSGfcIGCCEKSKLIDPKTVQPGDVFIgyKSDSFHANGWSlirrILEENPDVVDEEELRSLLQPTrlyHDVVEDMRRFNVTpKAYAHITGGGLPENLERFLGDYGADL-----SIPYWDNTAAQKILKHVDPqdrFNTFNMGIGwVAIVRPEDAEAALKA------GPGGTVIGTLREGRGIHVK---------------------
>UniRef50_A0RMV9(26-310:317) Selenide, water dikinase n=1 Tax=Campylobacter fetus subsp. fetus 82-40 RepID=A0RMV9_CAMFF  E=7e-06 s/c=0.19 id=20% cov=66%
------------------------------------------------------------------------GMIAAANSLSDIFAMGAK--AITAMNIV--GFDSchfenEILHEIMAGGKNKIKECGAVLVGGHS-IESKETIYGLSVT----GSVDSSKFWSNNSAKINDILILTKPLGSGVLTTALKADMLSLDEirEISNLMSQLNFYAVDALSGLKVNAVTDVTGFGFLGHLSEMLRD-DISFDLYKNGIPLLASAKKFAN-LGFIPegsyknsvftakicnikpdilLSDAqTSGGLIISINEDDAYKALSNLKNAGY-ESSCIVGTV------------------------------
>UniRef50_P22102(484-787:1010) Phosphoribosylglycinamide formyltransferase n=303 Tax=cellular organisms RepID=PUR2_HUMAN  E=7e-06 s/c=0.18 id=27% cov=68%
--------------------------------------------------------------------------------VNDILAQGAEPLffldYFSCG-----KLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDmyppGEYD---LAGFAVGAMERDQKLPhLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPdgcgdqtlgdllltptriYSHSLLPVLRSGHVKAFAHITGGGLLEniprVLPE---KLGVDLDAQTWRIPR---VFSWLQQEGhLSEEEMArtfNCGVgAVLVVSKEQTEQILRDIQQHK--EEAWVIGSVVARaegsPRVKVKNLIESMQI-------------
>UniRef50_A6G6A8(1-248:264) Selenide, water dikinase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G6A8_9DELT  E=8e-06 s/c=0.22 id=25% cov=63%
--------------------------------------------------------------------------------------MGGRPLWaLNLVFFPDDRLPLTVLRDIMRGSSQACAEAGVAVVGGHT--VRNGDL-KFGLAVTGMLEPDARRSLANTRAMPGQQLVLTKALG-TGIVASAIKKGVATPAQVDAAVRSMTRLNGEAAHAArrlGATACTDVTGFGLLGHLSNILEGSRLRAELELER---LPLLPGALEHLGAGIYPGGSkanlshvEGRlrrahastnnrafalthiaadaqtsggLLVAMPPDGAERLVEALRS--SGHPAAIVGE-------------------------------
>UniRef50_A2CCR8(373-634:730) Selenide,water dikinase n=8 Tax=Cyanobacteria RepID=A2CCR8_PROM3   E=8e-06 s/c=0.20 id=23% cov=65%
---------------AKLAEKPLNDALKQAGLGALgqqpEDAALI---ASTSSGDSLLQSVDGFpalISDPWLN-----GRLTTLHACSDLWASGAHVISAQAVITLPKvssELQQELLVQTLKGIQSTLEPQGAKLIGGHTleaRSIPPQPINlGIQLTLSVNGKVASGrVPWSKGKLQSGDVLLLSRPIGSgviFAAAMAGEAHPEDLDAALAQMTISQHNLLTALRSLEErhtgmqtIHACTDITGFGLLGHLGEMLSASN-------------------------------------------------------------------------------------------------
>UniRef50_B8GIC4(55-358:693) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Methanosphaerula palustris E1-9c RepID=B8GIC4_METPE  E=9e-06 s/c=0.18 id=18% cov=73%
------------------------------------------------------------------------------GIVRDVISMGAKPIALMDPLYfgpLTDEKNRYLFSHVISGISGYGNCIGVPVVRGEV-VFDEGYSGNPLVNVVCVGTVDPTKYLTARVKVPGNHLVLvgarTGRDGLGGASFASRDIAEDAEAVDRPSVQIGDPFTEkliidamlAMAATGKVLSCRDLGAAGLAGASSEMCSTFG-GI-IHAEKVHLRE-----TGMTALEIMLAESQERMLLEVAPEDVAQIGSLAERFDLCW--SDIGEVTSDPRYVVD--FHGEVVCDLPIDLLIdgaPR--
>UniRef50_A6W9Q5(217-416:479) GCN5-related N-acetyltransferase n=5 Tax=Actinomycetales RepID=A6W9Q5_KINRD  E=9e-06 s/c=0.27 id=23% cov=46%
--------------------------------------------------------------------------------LNDLAAMGATPVGMLDAL---AARDAHQAQRIVSGLRAAATAWGVPVLGGHTQL---GVPAALSVTALG----RTGSPVPAGGGRAGDEVRLTADLG--GGWRPGYRGAQWDSTSTRrgEDLRAMGSFVARSRPD----AAKDVSMAGLVGTLGMLAEASGTGAEIDVAAVP--------------------------------------------------------------------------------------
>UniRef50_A8KZL9(252-418:486) GCN5-related N-acetyltransferase n=3 Tax=Frankia RepID=A8KZL9_FRASN   E=1e-05 s/c=0.32 id=24% cov=48%
----------------------------------------------------------------------------WCGVlvnLNDLAAMGARPVGMLDAV---AGPTASRVARVIGGLRAAAERYGVPILGGHTQL---GVAAALSVTALG----RSERPIPAGGGLPGHAVTLTADLGGDWRPGYSGRQWDSTSNRRTAELRALLDLPRRHRP----CAAKDVSMVGIVGTLGMLAEASGCAAELDVAAVP--------------------------------------------------------------------------------------
>UniRef50_Q2W4S4(11-126:268) Thiamine monophosphate kinase n=2 Tax=Magnetospirillum RepID=Q2W4S4_MAGSA  E=1e-05 s/c=0.46 id=29% cov=34%
-----------------LIAELFAPlAAGFPGALGLTDDAAFIAAEP---GFDTVATMDSMVAGVHFLaddPPDLVARKLIRVNLSDLAAKGAEPRLLMLSAAFPRGVTQDWLRTFGAGLAEDVRAFGVHLIGGDT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q58MH8(58-330:331) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Prochlorococcus phage P-SSM2 RepID=Q58MH8_BPPRM  E=1e-05 s/c=0.19 id=22% cov=67%
--------------------------------------------------------------------------------VNDIITCGAKPLYF-LDYISTQKL-DDKIPDIMTGIIKGCEIAGMDLLGGETAEHPQYQM-KIDLAGFCTGIVEKKKIIDGSVIKPSDRIIGLASSGVHsnGYSIinyLARRLKLGYYShpELLTPTTIYAPVVERLLnEVEEVYGMSHITGGGIPENLPR-CLPKGLKAHVDWNAWSVPEiflEIQRQGNMDELEMRRVFNLGIgYCVIVPANRAELTMDIIRGE--GIECWEIGEVYEDK--------------------------
>UniRef50_D1ZBE4(492-745:762) Whole genome shotgun sequence assembly, scaffold_16 n=1 Tax=Sordaria macrospora RepID=D1ZBE4_SORMA  E=1e-05 s/c=0.21 id=28% cov=63%
--------------------------------------------------------------------------------VNDLVVQGAEPFmfldYYGCS-----RLDVSVAAAFVEGVAQGCKDAGCALVGGETAEMPDlYTGDDYDAAGAAIGVMKAAQRLPRkDAMAEGDVLVALASSGVHSNGFSLVRKVVDKCGLSYTDKAPwdssasvgeslltptriyVKPLLKVLAQTGeAVKGMAHITGGGLTENVprmlpKHLAAEIDVATwehppvfkWLRESVIP-TEMARTFNNGIG-----------MVLAVAPETADAVVKGLEAE--GEKVYTIGKLVNREG-------------------------
>UniRef50_A6G366(433-616:1010) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G366_9DELT  E=0.0008 s/c=0.26 id=27% cov=29%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLSSSVGEMAEATN-GARIDLAKAPLKYP--------GLAPWeILISEAqeRMTVAVPPAQLDAFLELAARREV--EASVLGEFTDDGRFRVD--YGALEVCDlslefMHDGVPLP---
>UniRef50_B1ZXJ1(471-666:1438) Phosphoribosylformylglycinamidine synthase n=12 Tax=Bacteria RepID=B1ZXJ1_OPITP  E=1e-05 s/c=0.27 id=23% cov=48%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------IKPGDKLVVLGgpamLIGLGGGAASSMasghgSEDLDFasvqrdNAEMERRCQEVIDRCWALGAENPIAFIHDVGAGGLSNALPELVNDGGRGGRFDLRKIPNDEP--------GMTPLEIwCNESqeRYVLAVPAGRIDTFKQLCERERC--PFAIVGEATEEKRLVLEDPHFANKPIDLPLEILLgkpPR--
>UniRef50_Q05728(129-386:389) Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic n=29 Tax=cellular organisms RepID=PUR5_ARATH  E=1e-05 s/c=0.21 id=24% cov=66%
-------------------------------------------------------------------------------SVNDIITSGAKPLFFLDYFATSR-LDVDLAEKVIKGIVEGCRQSECALLGGETAEMPDFYAEGEYdLSGFAVGIVKKTSVINGKNIVAGDVLIGLPSSGVHsnGFSLvrrVLARSNLSLKDALPGGSSTLGDALMAptviyvkqvldMIEKGGVKGLAHITGGGFTDNIPRVFPD-GLGAVIHTDAWELPPLFKWIqqtgriedSEMrrtfnLGI---------GMVMVVSPEAASRILEEVKNGDYV--AYRVGEVVNGEGV------------------------
>UniRef50_C9RR83(75-185:341) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RR83_FIBSS  E=1e-05 s/c=0.48 id=24% cov=29%
-------------------------------------------------------------------PGQDI----VNHCCDDILVQGARPLFFLDYVAtgrLEPGV----MDKLVAGMAKACRENDLVLIGGETAEMPgfYGPGDYD-ISGTIVGVVERENIIDGKKIKPGTIIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9XQX7(72-308:342) Phosphoribosylformylglycinamidine synthase n=1 Tax=bacterium Ellin514 RepID=B9XQX7_9BACT  E=1e-05 s/c=0.22 id=24% cov=64%
-----------------------------------------------------------------------------------LACSGAVPLGSTDNLNYGNPHNQEIFWQLkesVRGLAEACRAFNAPVTGGNVSLYnqnPNGPID-PTPTVAMVGLVEKPEHITTQWFKdEGNAIILLGDIVDTsdpllglGGSAYLQRIH-GKKTGTPPRCnldkeKELHLGLRSLIYSGVVKSAHDCSDGGLAVALAESCISQQVA---RETPRLIGADID-LSSITGtrLDALLFGeTQSRVIISVDKHQAGKVLG--QAKILGIPAIKIGSV------------------------------
>UniRef50_Q55946(44-299:322) Uncharacterized protein sll0787 n=15 Tax=Bacteria RepID=Y787_SYNY3   E=2e-05 s/c=0.21 id=20% cov=62%
--------------------------------------------------------------------------------VSDIYAMGGRPIAVVDALW---SKSSDQAQQIWAGMQAASARFNVPIVGGHTNTHSGYDALGVAI------LGRAKSLITSFDAQVGDRlILVSNFQGK-----PRPNAPYCWDAATMAETETLqkhWDLLPYLAENKLCDAGKDVSMGGIIGTALMLLETSKCGAILDLDAI--------SCPA-GLDFrqwlLSFPSYG-FLLSVRPQFVKTVKACFQAEGLIAEA--IATIQPGHNLTLK---------------------
>UniRef50_C7JIM3(44-299:323) Selenophosphate synthetase n=8 Tax=Acetobacter pasteurianus RepID=C7JIM3_ACEP3  E=2e-05 s/c=0.21 id=21% cov=45%
--------------------------------------------------------------------------------VSDIAAMGGRPVAVVDALWSD---TSEAAASILTGLHDGANTYGVPVVGGHTNMRSTHN----SLSVAILGRARH--LLTSFDAQPGEVLIAaidlrgrwhdphpfwdasSGLCGTEGAA--RLRGDIELLPTIAEDGLS--------------RAAKDISMAGLLGTALMLAECSGIGMTIMLDDIPRPED----------------------------------------------------------------------------------
>UniRef50_B4U7I6(82-248:336) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U7I6_HYDS0  E=2e-05 s/c=0.32 id=20% cov=43%
--------------------------------------------------------------------------------VNDIITTGSKPIafldYIAIGMI--EG---STINPLIEGIITGCEEANTPLVGGETAEMPSFYKDGEYdLAGFCIGICKKDEIVTGQDVKENDIIIAIPSSGFHSNGFSLVRyilekHNIKYNDYIKEFGKELWEIlltptriyvkdVLELKNKIKIKAMAHITGGGI-------------------------------------------------------------------------------------------------------------
>UniRef50_A5UWC7(87-339:341) Phosphoribosylformylglycinamidine cyclo-ligase n=6 Tax=Bacteria RepID=A5UWC7_ROSS1  E=2e-05 s/c=0.21 id=26% cov=66%
--------------------------------------------------------------------------------VNDILVQGARPLFLLDYLAV-DRLDPQRAATLVASVAAACREVGCVLLGGETAQMPDVYREGAFeLAGTIVGVVRRAQML-PRNVAAGDVILALPSSGLHTNGYSLARRVLGRGSAWGYDARPaelngrsigeallephrvyLRAFEQLEAAGVAVHAMAHITGGGIYEnlprVLPE-----GCGAVIRRRTWTIPPICTLVVQAAGLDereAFRTLNMGLGMLVIVPSDAADA-----ARRAVPEASPVGEVVTGGDVRL----------------------
>UniRef50_A1RQR1(66-306:307) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Thermoproteaceae RepID=A1RQR1_PYRIL  E=3e-05 s/c=0.22 id=24% cov=68%
------------------------------------------------------------------------GRDCVTVNVNDIVCDGFKPLAVVDYVAVEPQ-HLDKVPRVVAGVASKAGEVGAQLLGGETAVLP-GVIYGIDVVCTVLGIKAAYTRPPA----PGDVLIGLPSTGPHANGYSLLRRLFKPEEEVCGRPAAELLLAEVADYSPVLKAMEEDTvagavhiTGGGYRKLKK--ALGGLGAEVAFD-VPclFREIVKR-----GVEPheaYQVFNMGIgMVVYTTKDRLGEALRAL--EPL--NPRPIGEVKQGGGLLVNSII------------------
>UniRef50_C7M1V0(21-269:342) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M1V0_ACIFD  E=3e-05 s/c=0.21 id=24% cov=62%
---------------AQIVARTFTERVASPIGGF---GALYEIGGLGGARPTLVATTDGVGTKTEVARAGaryeGLGRDLVAMCVDDLVVTGATPLFFLDYLALgrvEPSL----VALLVDAMAAALGEVGASLIGGeiaeHPGVLEPGQVD---LAGFCVGIVDGDATLGSERVRAGDRVlgLRSPNLRSNGFSLVRRVYADVLEavargetGPLLADGRPLYdaliepsvlyaPLVLEFARAGLLHAAAHVTGGGLAGNL---------------------------------------------------------------------------------------------------------
>UniRef50_A5GQA4(372-678:680) Selenophosphate synthase fused with a FAD/NAD(P)-binding domain n=1 Tax=Synechococcus sp. RCC307 RepID=A5GQA4_SYNR3  E=4e-05 s/c=0.17 id=30% cov=44%
---------------------------------------------------------------------------------------------------------------------------------------------------------PGQLSWGKGPLRPGHVLLLSRPIG-TGVLFAAAQAGSAepqwLIAALEVMQQSQAPLVE-LLAAHGCSACTDVTGFGLLGHLNEMLDASmGVDVQLQADQVPAlagslelleagitstlapSNAVALArwPELLGtrarllIDPQTC---GPLLAAVPEQQAGPCLAAMRLAGF-SQAVRIGTV------------------------------
>UniRef50_B5IM46(21-318:328) Selenophosphate synthetase n=7 Tax=Chroococcales RepID=B5IM46_9CHRO   E=4e-05 s/c=0.17 id=23% cov=86%
-----------GKEEIQLPAGMF-PQLPFPGLGPAA-AIGDDAALIPASSGPLLLASEGmdpaLVEEDPWFAGWC----GVLVNLSDIAAMGGRPIALVNSLWASGETQARPL---LAGLRRAADTFAVPMVGGHTNLhSPYNALAVAVLGTA------PGPVLSARAARPGDRLhLLVNTQGR------LYRHYPFWDAATQAEPAMLrrhLALPVELAAAGLVRAAKDISMGGLVGTAEMFAEAAGCGLEIQLDELQPPAG-------LSLEAW-LTCfpSFGFLLAVPPERTAELARFTAPHPE-LLCAEIGRFLAGAPQVLLAAGAGRCPLRPPG--------
>UniRef50_B0XEZ0(14-324:336) Selenide n=4 Tax=Culicidae RepID=B0XEZ0_CULQU   E=4e-05 s/c=0.16 id=19% cov=83%
------------------IDKEGKSSTDNEGVGIGLDSSVIPLKNDL----QLVQTVD------FFYPLIDdphmLGRIALANVVSDVYAVGA--LAIdEIKLVCSAPTEFSEAERdivvpmIIRGFQEAAAEAKCPAKIGSIALNP-----WCIIGGIATAVCHKSELIMPYNAQPGDALVLTKPLGTQLAtnAFIWMTEEAENWTKLAAHLTPaeversyaiavesmsrLNRSGAELMHKFGAHAATDVTGFGLFGHAENLLKFQKADVDFELDTLPIIRNVVKIAEILGRTPKLMAGKavetsGGLLLSLPAENAEKFCAEYRTVSEH-DAWIIGKVVPGSRVL-----------------------
>UniRef50_B2GFL3(79-286:370) Thiamine-monophosphate kinase n=1 Tax=Kocuria rhizophila DC2201 RepID=B2GFL3_KOCRD  E=5e-05 s/c=0.25 id=20% cov=51%
--------------------------------------------------------------------GADLGHKCAAQNLADVAAMGAVPTAVVVSLTMPGDTPVAWVTDFARGLSRAFESLGAwecALVGGDL-----GRGAELSITATVLGRCETAPVLRSGAGAGGVLVhagvlglaaaglaVLEGAVPEASGALTGPERRMLVEAQLRP--QPPVPAGPALARA-GATAMLD-VSDGLLRDARRIARASGVRIDLDPDAL---------------------------------------------------------------------------------------
>UniRef50_Q2S2H8(84-206:337) Phosphoribosylformylglycinamidine cyclo-ligase n=10 Tax=Bacteroidetes/Chlorobi group RepID=Q2S2H8_SALRD  E=5e-05 s/c=0.42 id=31% cov=26%
--------------------------------------------------------------------------------VTDVAVCGARPLYFLDYYgvgTLEP----DTAEAVVEGFATACDDNDCALVGGEIAEMPDvyGEGDFDLVGTV-VGLVDKGTIVTGDEVRPGDVLL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1J913(83-322:334) Putative uncharacterized protein n=1 Tax=uncultured archaeon RepID=D1J913_9ARCH  E=5e-05 s/c=0.21 id=20% cov=68%
--------------------------------------------------------------------------------VADISAMGGTPLAMvNLTSTQEKGICAE----LGQGMADGVRKFGVPMVGGH--LHPDTNYDAL--DVAIMGTVKRDCVIFSSGAKPGDKVLVAIDI-DGGI---YPSYNLAWDNTTRRTVAEIKKQLDTMVEIGEkklATAGKDISNPGTLGTFGMLLESSGAGAVVELDKIPRPDL------DIPFEQWLKMYPGTgFVLTVENDDnAAECIRIF--EDAGVATSIVGEVDASKKLKITNGTETATVFDL----------
>UniRef50_D1B9U1(28-342:344) Selenide, water dikinase n=3 Tax=Synergistaceae RepID=D1B9U1_THEAS   E=5e-05 s/c=0.16 id=24% cov=76%
-----------------------------------------DAALWRIGEGRLAIlTVDfitPIVDDPLTF-----GEIAAANSLSDVFAMGGSPK-VALNLVAFPTScePLEVLSQILEGGARKVMEAGACLAGGHS-VQDEEPKYGLSV----YGEVDEGGLWRVTGAREGDSLILTKPVGS--GIITTASKGGVAEGDWL-DQAVQW--MRMLNNVPGrmdrsllgnVRAATDVTGFGLLGHCMDMLSHRELDLVIHHDQVPfidgafqmasmgmvpagaysnrghvehrvlMSPNVPLAVQDILFDPQTS---GGLLLAVAPGSEKEVLSQLWELGFHR-AATVGRFIKGEGKVL----------------------
>UniRef50_D1JHF1(59-341:362) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=environmental samples RepID=D1JHF1_9ARCH  E=6e-05 s/c=0.18 id=20% cov=67%
--------------------------------------------------------------------------------VNDILCVGAEPISLVDYIALCEPDP-ELLEEIGKGLLKGAEIANITISGGEIAIV-KDMVKGVRKNrefdlvGTAVGTVSLDKVIVGANIQEKDVIIGLSSSGIHSNGLSLARhiflktgaidEHFDvLEKTIGAELLEPTHiyvpeIMEMINSNLDIKALMHITGDGF---LNLTRVKSEVGFVIEylPETPPIFTLLQKRGNVTDEEMFRVYNMGIgFCVILPEQEAEVAIEIASRHKV--DAFRLGYVVKDP--------------------------
>UniRef50_C7NKL2(67-284:357) Selenophosphate synthase n=13 Tax=Actinomycetales RepID=C7NKL2_KYTSD  E=6e-05 s/c=0.23 id=20% cov=49%
------------------------------------------------------------------------GRIAAANALSDVYAMGGTPV-MAINLVgwPRAALPMELLTEVLAGGLEIATQAGCPVIGGHSIDSP-----EPIYGMAVTGTADPDRLLRNDAAEPGLPISLTKPVGlgilnnHHKTTGALHPHAIEVMTQ-------LNAAASRAALQAGVRAATDVTGFGLLGHLFKMCRASAVAACIDAGAVP--------------------------------------------------------------------------------------
>UniRef50_A3EU85(81-345:350) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Leptospirillum RepID=A3EU85_9BACT  E=6e-05 s/c=0.19 id=23% cov=60%
---------------------------------------------------------------------------------NDIAVMGAEPLFF-LDYYASGRLDPEVGKRIFSGIAEGCRQAGAALLGGETAEMPGVYQDADF-DLAGfvVGIADREKIVDGRKIGLGHRLYGLPSTGIHSNGFSLVRKVLIEERGISPGDRPEWspgedwshiltrptriyvPLILEMIARVEVSAMVHVTGGGLTEnvprVLPE-----GFSARINPrawEKPPVFQEIQKAGKVTTREMFQVFNMGIGLVVVVPSEAGKALE-----------------------------------------------
>UniRef50_B0S0R2(15-272:341) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=Bacteria RepID=PUR5_FINM2  E=7e-05 s/c=0.20 id=21% cov=48%
-----------GYEEVQIIKEIVKKTHGKEVLTGIGGFAGLFKPELTDMKEPVLVSgTDGVGTKIKLAMELDkhdtvgIDLVAMC--VNDVLCQGAKPLFF-LDYIATGSLKPAKMADLVRGVAEGCSQSECALIGGETAEMP-----GLYkendydLAGFAVGIVDRDKIIDGSGIKEGDVAISLSSSGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5HSS7(43-333:340) Selenide, water dikinase n=16 Tax=Campylobacter RepID=SELD_CAMJR   E=8e-05 s/c=0.17 id=17% cov=38%
------------------------------------------------------------------------------------------------------------LKELLEGANDKVQECNALVVGGHTI-----ESTELFFGLSVTGKVHPSKFIANNTSKIGDCIILTKPLG-TGIlstalkAQMLNQKHLDI---------MLKNMMELNYKASQIAlkfhpsAMSDVTGFGLLGHLKEMLNK-NISFEIFQNEI---------------------------------------------------------------------------------------
>UniRef50_D1B9N9(83-329:331) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Thermanaerovibrio acidaminovorans DSM 6589 RepID=D1B9N9_THEAS  E=9e-05 s/c=0.20 id=21% cov=65%
--------------------------------------------------------------------------------VNDLVTCGARPLFF-LDYVACGSLDVEALSPILESIVESCEESGCILLGGETAempwVYPPQGFD---LAGFAVGIVDIDQIVTGGNIEEGDLLLGLRSSGIHSngyslVRLAVERARLDLTQPQPGFQLPLGEELlrptklyvraaMEALSTRKVKGMAHITGGGLEGNVSRIIPR-GLRAQVDYSSWD-RPLIFRLLRELGIEEEEMRrvfNLGIgFVLVASPDHLPEVADALARC--GEEFIVIGRVS-----------------------------
>UniRef50_B3SBH6(474-628:1024) Putative uncharacterized protein n=1 Tax=Trichoplax adhaerens RepID=B3SBH6_TRIAD  E=0.0001 s/c=0.32 id=25% cov=26%
-------------------------------------------------------------------------------SVNDLLARGAEAVAM-LDYISYSSLGKEVIQAILSGIATGCRIAGCALVGGETAQMPGlypvGTYD---LAGFAIGYVERGQDLPeIDTIIPGDKVI---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q46E56(25-185:333) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=Euryarchaeota RepID=PUR5_METBF  E=0.0001 s/c=0.31 id=20% cov=46%
-----------------LIEKL---SYVRKGMGAPLTGIGHYAGLLDFGEYALALTTDGVGSKVLIanemqrWNTVGIDCIAMN--VNDLLAIGAEPVAFVDYLALekhEEGFA----AQIGEGLVKGAEISRMSIVGGETATLPE-IIKGFDLAGTCLGIVRKDEIVEGEKVRVGDVIVGVPSTGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3MXE8(60-307:309) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Pyrobaculum RepID=A3MXE8_PYRCJ  E=0.0001 s/c=0.20 id=25% cov=69%
------------------------------------------------------------------------GRLEVAGwdclfvNVNDVVSDGFKPVAAVDYVAVSPGLEDA-VPPVFEGLRKAAQRANVAVLGGETAIMP-DVVNGIDV----VCTILAKRVAAPKRPAPGDYLVALESTGPHANGFSLLRRIFKLGerlcGSTVEDilLAPVadYGAVVEMLKEGVVKAVAHIT-GGAFAKLKRV--LGDLGAKLELGNLPCwAEEVvkRGVPRE---EAYRVFNMGVGMVLVT-DTPNDALR--RAEDLGLRARVVGRVKEEGPVAVDGVV------------------
>UniRef50_C1TPV7(83-329:330) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TPV7_9BACT  E=0.0001 s/c=0.20 id=26% cov=59%
-------------------------------------------------------------------------------SVNDLITCGARPIlfldYLACG-----KLDSDRLIPVVEGVMDACLESGCALLGGETAempgVYPPNGFD---LAGFAVGTVDREDLIDGSCVERGDLMIGLASSGIHSNGYSLVRKALEKElaaslhekidqlGETLSD-ALLKPtrlyprPVLSALKTGKIKAMAHITGGGLEENI--------------ERALP-----KGMLPEIDFDSWnrpaifdYISNRGVdesemrrvfnlgigYTLVVAPENRDEVTEKLR--EKGETPVVFGTV------------------------------
>UniRef50_B3V648(18-345:348) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=uncultured marine crenarchaeote KM3-153-F8 RepID=B3V648_9ARCH  E=0.0001 s/c=0.15 id=20% cov=89%
------------KSSHSEISKLLGStlSLRNGRIGEVIAGSGHYAGVIkLRNDDYLALHTDGVGTKVLIaqqyskFDTVGIDCIAMN--VNDLICVGAEPISLVDYIALKKNNPV-LVKEITKGLVKGAKLSNTPIIGGETAIMPdviEGYGNKAFdLAASAVGVINKKTNMLNRKIKSGDIIIGLQSSGIHSNGATLARkvllEKYSLRKKmykskrlgdllLEPTIIYSKAIMTILNNIKSIHGLAHIT-GGAFTKLPRIGSG-RVGFSLDLPKPPfIFELIQETGNISDKEMQRTFNMGYgFVIICPKSQYVNVDSIL--SEYKINNTILGNIVSHRGVKVNGK-------------------
>UniRef50_Q65RJ7(416-606:1297) Phosphoribosylformylglycinamidine synthase n=45 Tax=Bacteria RepID=PUR4_MANSM  E=0.0002 s/c=0.26 id=22% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAFIHDVGAGGLSNAMPELVHDGGRGGKFELRNI--------LCDERGMSPLEIwCNESqeRYVLAVAPENLAVFEELCQRER--APYAIIGEATEEEHLTLHDNHFDNNPIDLPMSLLL----
>UniRef50_B3E0M2(96-373:762) Phosphoribosylformylglycinamidinesynthase, synthetase domain n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3E0M2_METI4  E=0.0002 s/c=0.18 id=24% cov=53%
----------------------------------------------------------------------------------DILTMGAQPLCFMNSLrfgeIREEKSPGANhnaflLRHVVAGIAHYGNCVGVPTVGGELA-FDKSYEDNPLVNVFCLGVVKTERIQRGVAQGIGNPVFIagskTGRDGLKGAAFASrkleenkaeQRHSVQIADPFMG--RILMSACLELFQIPGVVAgIQDMGAAGLICSTSETAARAKRGMEINLDEVPVREEDMSAEEIL--------------------------------------------------------------------------
>UniRef50_Q9RXT4(481-721:747) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Deinococci RepID=PURL_DEIRA  E=0.0002 s/c=0.20 id=27% cov=65%
-----------------------------------------------------------------------------------LACVGATPLAITDNLNF--GNPHRpevyyQLQQAVQGIADACRALNTPVTGGNVSLYNQyTEGDhKVAIhptPTIGmVGVLPDVTVRASLNLKaAGQTLLLLGHRAEKGwsDSIgasqyLETVHGLEAGQVPPVDLDLAQKVVDgtlALIRAGLTDTAHDCAEGGLAVALAEMAIAGGLGLNVSLDA---PASVRA-------DALLF---GEAHSRVIVAVEDAAAAGAKLDELGLPYAVLGETVEAPKVTIAAP-------------------
>UniRef50_C4ZDB0(10-339:342) Selenide, water dikinase n=22 Tax=Bacteria RepID=SELD_EUBR3   E=0.0002 s/c=0.15 id=25% cov=72%
------------------------------------------------------ISDDTAVVQTLdFFPpmvddPYTFGQIAAANALSDIyAMGGTVKTALNI-VCFPEKMDLNILGKIMQGGADKVIEAGGTLAGGH-----SIADSDVKYGLSVMGTVHPEHIYSNNTGQPSDVLILTKKLGV-GLVCNANRVGeapLGAIEDAVSSMTTLNKAASEISHAFDIHACTDVTGfsflGHLSEMLND-----DITALIDSISIPVitgalrcadeffltaaaqrnRNHVGDkVCfaknipfsmEEVLFDPQTS---GGLLFAVKASEADAFLHELKAA--GLPAAKVGRFVKRRDV------------------------
>UniRef50_C7XXZ8(55-317:347) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Lactobacillus coleohominis 101-4-CHN RepID=C7XXZ8_9LACO  E=0.0004 s/c=0.18 id=19% cov=60%
--------------------------------------------------------------------------------------SGAEPLAITDCLNYGDPNDPEIFWELhhsIEGMATACRIFDTPVISGNVSLYNENNGRSIY-PTPMVGMVglikNLDHVIPSFATHAGDDVYL---IGQTGNDYAGSELQKLMTGQISGTLSKVNlqriqeycGRLHSEMVAGHVTAAHDVSEGGLGVAFAEMLFAGETGMNL---------------DLRDLTATQLFSEtaGRMIVTVPSAFKTEFEDAM-----GNDAQWVGTVTNTH--------------------------
>UniRef50_B9LUY3(44-329:343) Phosphoribosylformylglycinamidine cyclo-ligase n=12 Tax=Halobacteriaceae RepID=B9LUY3_HALLT  E=0.0005 s/c=0.17 id=25% cov=64%
--------------------------------------------------------------------------------VNDLVAAGVRPVAFVDYLAVDE--PDERFaEQVGEGLARGAELADMELVGGETAVMP-DVIRGLDLAGTCAGLAAKEAVF-DGAAEPGDALVGWRSSGIHSNGLTLAREAATREHAYTDPCpfdgyetvgeALLEPtriytdLLDPMRDH-GVRGAAHVTGGG-WTNLTRLGANRYVVDDAFEPQ-PVFEFVQSEGSVSDEEMHRTFNMGTgFVAAVDPDAAESLAAE-------TDGRVIGRVEEG---------------------------
>UniRef50_UPI000194E500(487-603:1015) PREDICTED: phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase n=1 Tax=Taeniopygia guttata RepID=UPI000194E500  E=0.0007 s/c=0.41 id=31% cov=28%
--------------------------------------------------------------------------------VNDLLAQGAEPLFflshLACG-----KLNAEVMETIKEGIAEACRSAGCAFLGAEVTEVaapcPPGHCD---LAGFAVGAVERGQRLPGlQRAEEGDALLGLGSAAIHG------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5FPS3(66-216:354) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=Dehalococcoides RepID=A5FPS3_DEHSB  E=0.0008 s/c=0.31 id=22% cov=28%
----------------------------------------------------------------------------VNHSVNDILTSGAEPIFF-LDYIAMGKLSPGKITEIVKGLSTACLEAGCALIGGETAEMP-GLYHGEDYDLAGfiVGVVEKENMLINRGIKPGDIIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8V0S2(524-655:809) Phosphoribosylamine-glycine ligase (Eurofung) n=27 Tax=Saccharomyceta RepID=C8V0S2_EMENI  E=0.0009 s/c=0.36 id=38% cov=28%
--------------------------------------------------------------------------------VNDLVVQGAEPLFFldcySCG-----KLDVETAAAFVTGVADGCIQAGCALIGGETAEMPGLFIDDTYdavgaavgaINTS--GPNARTILPDTSSMKAGDVLLALASSGPH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2JL07(54-189:354) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Synechococcus RepID=PUR5_SYNJB  E=0.001 s/c=0.35 id=24% cov=26%
---------------------------------------------------------------------------------NDVLTVGARPLFF-LDYVATGKLEPEALWQVIDGILAGCQEAGCQLLGGETAEMpgfyPPGKYD---LAGFCIGIVEKTAILDGSRVQLGDRLL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6PIR8(1-329:329) Hydrogenase expression/formation protein HypE n=3 Tax=Bacteria RepID=C6PIR8_9THEO  E=2e-91 s/c=1.03 id=49% cov=98%
MDKVLLSHGGGGTMMESLIEEVFSKAFDNEYIKGMEDAALL--------FGNITFTTDSFTVKPIFFPGGDIGRLAVCGTVNDASMRGAKPLYLTSAFIIEEGYPMEDLKKIVKSMAETAEEAGVKIVAGDTKVVEKGGVDGVFINTSGIGVVYENVDVSIKNAKPGDVVLVSGTIGDHGMAIMSAREELQFDPPILSDVSPLNKLIEKLMTLGkAVKVLRDPTRGGVAEVLYEISKMSGVGIKIYEDKLPVKDSVKHACEMMGFDFLHLANEGKLITVIDRKYAEEALEIMKSDKYGKDAAIIGEVNDSKLVTINTIYGTSRIVDRPIGELLPRIC
>UniRef50_A8ZNR3(17-362:362) Hydrogenase expression/formation protein HypE n=17 Tax=Bacteria RepID=A8ZNR3_ACAM1  E=1e-87 s/c=0.94 id=44% cov=98%
--QVLLAHGGGGKLMHQLIEQMFGRLFQSE------DRHHHDAAVLGVPPGRLALTTDSYVVHPLFFPGGDIGSLAVYGTVNDLAMAGARPLYLSTSFILEEGLSMTTLWQVVQSMQQAAHQADVQIVTGDTKVVERGKGDGVFINTAGVGIIEHHQTIHPQSIQPGDLVILNGDLGRHGMAVLAEREGLEFESEIKSDSAPLNHVVLDLFAHGvELHCMRDLTRGGLASALNEIALATGVAISLDETCIPIREDVQGACEILGFDPLYVANEGRFIAFVPPQSVDLALARLNAPlsfplsgqsdthpqmRHQHPAQVIGQVttTTSPRVTLTNRLGVERIVDFLSGEQLPRIC
>UniRef50_P31905(33-351:351) Hydrogenase expression/formation protein hypE n=17 Tax=Bacteria RepID=HYPE_RALEH  E=2e-81 s/c=0.96 id=50% cov=94%
----------------QLIQELFVAAFDNEWLRQGNDQA----AFAMPAGARMVMATDAHVVSPLFFPGGDIGSLSVHGTINDVAMAGAKPLYLAASFILEEGFPLADLKRIVESMAGAAREAGVPIVTGDTKVVEQGKGDGVFITTTGVGVVPAGILIDGAGARPGDAILLSGTMGEHGVAILSKRESLEFDTEIRSDSAALHDLVAQMLAvVPGVRVLRDPTRGGLATTLNEISSQSGVGMVLDEAAIPVLPQVDAACELLGLDPLYVANEGKLVAICAAADADALLAAMRGHPLGREARRIGEVIEDGRhfVQMRTKFGGMRVVDWLSGEQLPRIC
>UniRef50_C9LR03(2-327:327) Hydrogenase expression/formation protein HypE n=1 Tax=Dialister invisus DSM 15470 RepID=C9LR03_9FIRM  E=1e-79 s/c=0.92 id=43% cov=97%
--KITLKHGSGGEESGRLIKDIFASVFDDEILLKMEDSAVL-----PPLHGNPVLTSDSFVVEPLFFKGGDIGKLSVCGTVNDLSSMGARPLYLTASFILETGLDTDILGKIVQSMKETAEEAGVRIVAGDTKVIE--GKGGLYINTAGVGERPSSRDISCRNMKSGDTLILTGTLGDHHAAVLTNR--LGIESEIESDCAPLNHMVEELLEgNISVHTVRDITRGGLATVANELAVSSSVRIELEEELIPVSDIVQGFTGILGLDPLTMGNEGKMIIAVSPKDAEKAVGILRRNKYGRNAVAAGQVLEGKGVYLRTALGGLRRVLPLRGEGLPRIC
>UniRef50_C7NVH7(29-365:365) Hydrogenase expression/formation protein HypE n=1 Tax=Halorhabdus utahensis DSM 12940 RepID=C7NVH7_HALUD  E=1e-77 s/c=0.87 id=40% cov=98%
---ITHAHGAGGGQMTELVDAVavsqFADAAADVGLAALDDGSV----QPIDDDHSVVVTTDSHVVTPLFFRGGDIGRLAVSGTVNDLAMMGAtEPLALTSSLIIEAGTPQTTVERVTESMREACEEAGATVTTGDTKVMGSGEMDTLAINTTGVAVVPKGGHVPDAGLSVGDRLIVSGTVGDHGISLLSEREGFDFGGDLESDVQPVNDLVRAAMDAGEVTAMKDPTRGGLATVLNEMASKADVGIDVEERSVPVSGPVSSAGEVLGIEPFDVACEGVVVMGVASEDAADVLDALRDNPKGEDAAIVGEVVDDHtGQVVLDTGFGRRYLSPPEGEQLPRIC
>UniRef50_B5Y920(1-319:319) Hydrogenase expression/formation protein HypE n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y920_COPPD  E=2e-76 s/c=0.90 id=40% cov=95%
MDKITLSIGTGGEEMTQFLQKTVFPILEESISG---DAALV---------NHTAFTIDSFVAEPPFFPGGSIGTLAVSGTVNDLVAAGAKPSALALSLILEEGLDMEVVRRILQDAKETAKLAQIKIVTGDTKVVQKGAADKVFVTTSGIGQ----KVLDFESPAPGDAVVVTGDIARHGATMLLASKKFELESQLTSDCEPLCWLIDVLKPFEGfLKWMRDPTRGGVGTILHEFCSQFSLGVRLFQKQIPIMPEVKGICELLGLEPLHLASEGRMVIVISPDKAHEFLESLK--PFAPNASVIGEVVDDHKTLTQVVDGYETYVPPLTGEILPRIC
>UniRef50_D2LQB8(3-339:339) Hydrogenase expression/formation protein HypE n=3 Tax=Aciduliprofundum boonei T469 RepID=D2LQB8_9EURY  E=3e-75 s/c=0.84 id=35% cov=99%
LDRIRMVDGAGGEAMERLIKEIILDNITLRSAGKVSLDDLDDGATISLDGEDIVFTIDGHTVKPIFFPGGDIGKLAVSGTVNDLAVMGAKPLALAISLIIEDGFSMDSLKNIMISIDKTGKDVPVPIITGDTKVVE----DKIGIFAISAGIGKADKIVRDSGARVGDFVLINGGIGEHGFAIMSKREGIDFETSLVSDVSPLWSLIEDVAKCIGwenIHAMKDPTRGGLSEALNEMASKANVGIEIDEESVPIKSSVKAASEMLGISPFIMANEGKVVMIVADGYQDDAIEAMRKNKNGKDAAIIGRVIREypGKVIIKTKIGGKRFIERPIGDPVPRVC
>UniRef50_A4TCL4(53-373:373) Hydrogenase expression/formation protein HypE n=15 Tax=Bacteria RepID=A4TCL4_MYCGI  E=3e-72 s/c=0.85 id=45% cov=95%
-------------MSGELVEHLFLPAFGSAAEAGLADSAVVEIG-----GARLAFSTDSFVVKPMVFPGGTIGDLAVNGTVNDLAMAGAVPAVLSTAFILEEGTALDHLARVAQAVGTAALAAGVKLVTGDTKVVDSGHGDGVYINTTGIGLVDPRVDIRPQRAAPGDVVIVSGDLGVHGIAVLSCREGLEFATSVASDAAPLHGLVAAMVETGAdIHTLRDPTRGGLAATLNEIARAAGVGVSIADTALPIPQEVRDACSMLGLDPLYVANEGKLVAFVPAADADEVLAAMHAHPLGAQSAVIGTCVPDHPgmVVAKTALGGNRVVDLPIGEQLPRIC
>UniRef50_B1YBW5(25-366:366) Hydrogenase expression/formation protein HypE n=7 Tax=Archaea RepID=B1YBW5_THENV  E=1e-70 s/c=0.79 id=38% cov=98%
---IKLSHGSGGVETSEIVEKLFLRRLPEglkkVAGGLGLDFPDDAAAIPMADGRYLVVTVDAYTVNPPFFPGGDIGMLAASGSINDVLMLGGRPLAMLDSIIAEEGLPYETLDRVVKSFLSVLEAEGVALIGGDFKVMPKGQLDKIVITTVGIGVADR---IIVDKPRHGDKIVVSDFVGDHGAVILMLQMGDVDKPEqlqLKSDVKPLTKLMVPLVEKYGeyIHAARDPTRGGLAMVLNDWAKAGGGVIVVEEESLPVRPEVASYAGMLGIDPLYLASEGAAVLAVDPAVAEEVVKFMRGLGF-QNARVVGEFREarqhRGYVLLKTVAGGLRILEPPRGDIVPRIC
>UniRef50_B8D3R7(8-349:349) Hydrogenase expression/formation protein HypE n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D3R7_DESK1  E=8e-67 s/c=0.75 id=32% cov=98%
-KIITTLHGAGGIESWNIIEKLIRGRVPRDLwstPGGAGLDVLDDGSYIRIGESYIVFASDAYTVKPLFFPGGNIGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELEDIVDSMVKTLVENNVALIGGDFKVMPRGSVDGVVISGFAIGVSGKPPVVDS--IKPGDKIIVTNYIAEHGSTILAAQldmlnDAPGLKSDVKPLVKTVLPVIEEYRDY--INAARDPTRGGLAAILNEWSRSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEALRRN--GENPYIIGEVVEprsrelRGRVVALTEVGGLTII-PPQAYNLPRIC
>UniRef50_A9KBN8(8-303:320) Thiamine-monophosphate kinase n=5 Tax=Coxiella burnetii RepID=A9KBN8_COXBN  E=2e-57 s/c=0.76 id=23% cov=85%
-----------------IIENYFhrpKKPAKNVVVGIGDDAAVIE----IPKEQQVVISVDTLVEGVHFpinTPPRDLGHKALAVSLSDIASMGAIPHTVLLALTI-QKTNEIWLKAFAEGFFSLADRYQVSLIGGDVTQGP------LCISITATGLIPKNEMICRNGATVGDLIYLTGTVGDAGLALALLKQNKKIDPFLLTRLNCPTPRIEAGVALRGIASAAIDISDGVVADLEKMARASQVGAKIYVERLPLSDSLKRYCPLkkAWEYALTSGDDYELCFTIPKERSEPLEEVF--HSLDCECRCIGEIIQGESVTV----------------------
>UniRef50_C7G8J7(8-330:331) Hydrogenase maturation factor n=4 Tax=Clostridiales RepID=C7G8J7_9FIRM  E=1e-54 s/c=0.67 id=25% cov=84%
----------------------------------GEDCAAVKLA----EDETLVMSTD-----PITGTAQDIGTLAIQITANDLASAGAEPVGVLLTVLLPPEIEEPDLREMMQQVEAACAKAGVQVMGGHTEI--TAVVNQPVISVCGVGKVKDGCLISTGGAKPGMDILVTKWIGIEGTSIIAKEKEKDLLTRFSAPFIENAKKLDvylsvlseaAVAVRSGVSAMHDVTEGGIFGALWEMAEASGVGLEIDLKKIPVRQETIEICEFFGINPYELISSGSMLMAAADGNL--LVNELKKA--GIPATIIGKATAGNDRVLLNED-ERRFLEPPKTDEL----
>UniRef50_B7R791(21-340:348) AIR synthase related protein, C-terminal domain n=2 Tax=Thermoanaerobacteraceae RepID=B7R791_9THEO  E=7e-53 s/c=0.66 id=24% cov=93%
-----------GKIPVEVMKRSIFPYLGTKRKEVLVHSQLGEDSSIIDFGEYVAV----LSTDPITAADKLSGFLSVIISCNDLAACGAEPIGILTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGGHTEV--TQAVNKPVISTTAIGIARKGKYITSKGAKIGDDVIVTKALGLEGTAILATDYEDLLIKHFGKDFVLkaqsfinEISVIEEGLIASqnGANAMHDITEGGVLGATYEISEASGLGIEIYEEKLPFRRETKEICKFFGLNPLKLISSGSMLITA--EDGNRIVKALS--EKGIQATIIGKIVKE-GRYLITSSGKEEIL-PPEKDEIYR--
>UniRef50_Q0K6Z2(55-365:381) Thiamine monophosphate kinase n=114 Tax=Proteobacteria RepID=Q0K6Z2_RALEH  E=2e-52 s/c=0.67 id=23% cov=90%
----TMSHAQPAPLSEfDLIRRFFTRPVRKAALGVGDDCALIEG----RPGHHLAISTDMLVSGRHFFPdvaPRSLGHKALAVNLSDLAAMGAEPRAFTLALALPEA-DPAWLAELADGMLALADAHGCELVGGDTTRGP------LTLSLTVFGDVPLRAALRRDAARPGDDIWISGTLGDARLALGDCRGEWLLPepefSQVRPRMDTPTPRVALGMALRGVAHAALDISDGLVGDLGHILERSQVGALVDVDALPRSAVLASQPDAIQREcVLAGGDDYELCFTAPAGSRDAIAAI--SERLALPLARVGAITPEPGLRLVDSTG-----------------
>UniRef50_C4LAD9(5-311:328) Thiamine-monophosphate kinase n=1 Tax=Tolumonas auensis DSM 9187 RepID=C4LAD9_TOLAT  E=3e-52 s/c=0.67 id=24% cov=85%
----------------ELIQHYFaaqAAARADVELGIGDDCALLNVPV----GECLAVSTDTLVSDVHFFADVDpvaLGHKALAVNLSDLAAMGAQPRWISLALTLPKADDV-WLTGFTQGFHALAVKHNVALIGGDTTRGP------LSITISAKGTVPAAQALRRSGAKAGDAIYVSGSLGAAALAVQQRIHNLPINSDALRDCsfrmDYPQPRCELGLALRGIATSALDLSDGLSGDLMHILRASGVAAEIELTNLPIASAVQRSVtpEQALQLALGGGDDYELCFTVPAGHETAISEL--AVALDLPLTRIGTITTGEPQII----------------------
>UniRef50_C9RAP1(11-323:339) Thiamine-monophosphate kinase n=1 Tax=Ammonifex degensii KC4 RepID=C9RAP1_AMMDK  E=5e-52 s/c=0.66 id=27% cov=84%
-----------------------------PSAREVIQGVGDDAAVLAVGDKWFLFTTDVLVEKVHFrwdlASPADVGFKTLAVNVSDIAAMGGRPTYALVTLGLPLDFPVEKVEEFYAGLKEAAEEYEVILVGGDITRS-----DIFFAGVALLGEVEPGKAKFRKGARPGDILCVTGPLGGAAAGLVLLESKEELLPEtmahfLRRKYRRPDARLEAgriLGDFEEVHALIDISD-GLAGDAHHLARASGVEVNLYRAALPIYPPAQELGRRLGIDParwaLFGGEDYELLFTVEPSAVGKVAKAL--EGVGLNLFPLGFVEEGEGVKLVLPDG-----------------
>UniRef50_A1HSU1(28-339:346) Thiamine-monophosphate kinase n=1 Tax=Thermosinus carboxydivorans Nor1 RepID=A1HSU1_9FIRM  E=5e-52 s/c=0.66 id=25% cov=84%
----------------DLIQTDAIQEPGTVVVGIGDDAAVL----LPTPRQLQLLTADMLVEGVHFdlgrTTAWQLGYKAIAVNLSDIAAMGGVPRHAVISLALPRQIPVEFVVNLYQGMKEICREFRVNIVGGDTVASPHG----LIINVAVMGEVEPTQLVRRSGAQVGDMVAVTGVLGSSAAGLDLLSldnwAEYDFAWPLVTAHLTPRPQVKAGQLLGLYgATSMDDISDGLASEAHEIAKASKVGLRIEAKLVPLAPELKQAAAMLGKEPldyaLYGGEDYQLVFTIGREK----LQALSAVDFGVPLTVIGEVTE----------------------------
>UniRef50_C0ZK37(7-310:338) Thiamin-monophosphate kinase n=1 Tax=Brevibacillus brevis NBRC 100599 RepID=C0ZK37_BREBN  E=4e-51 s/c=0.67 id=21% cov=54%
----------------------------------------------------------------------DIGYKAVISNVSDVAAMGGVARYALVSIAVSPQWTPDECQQIYEGIYEACQAYGVRVIGGDTVSAP----DALHLSVTVLGEVEKGRAIRRSQAKPGQLVFVTGHVGTSAAGLHLLLQGETAErgvsaswETLMDAHQRPVAQIKAgrLLLESGACSALNDVSDGLASELWEIAEASGVSILVDAATVPIHDEVR--------------------------------------------------------------------------------
>UniRef50_B0KA39(4-321:331) AIR synthase related protein domain protein n=10 Tax=Clostridia RepID=B0KA39_THEP3  E=5e-50 s/c=0.63 id=22% cov=92%
-----------GKVPVEILKRSVFPYLGVKRKEVLVHSQLGEDSSIIDFGEYVAV----LSTDPITAAEKLSGFLSVIISCNDLASCGAKPIGILSTILLPEGSDESVLHNLMEEIDKAAKKLNIEVLGGHTEITTT--VNKPIISTTAIGMAKKGEYITTKGAKIGDDVIVTKALGLEGTAILATDYEDLLLKRYDKDFILkaqsfinEISVIEEGLIAAqnGANAMHDITEGGILGAAYEIAEASGLGIEIYEEKLPVRPETKEICRFFGINPLKLISSGSMIITAS--DGDKIVKSLS--EKGIQATIIGKIIKE-GKYLITSKGKEEITPPERDEI-----
>UniRef50_A0M637(20-338:351) Thiamine-monophosphate kinase n=43 Tax=Bacteroidetes RepID=A0M637_GRAFK  E=1e-49 s/c=0.62 id=22% cov=86%
-----------------LIDHLTKNF--SPKLESTIKAIGDDAAVLNFKNKQTLISTDLLVEGVHFdlayMPLKHLGYKAVMVNLSDIYAMNGTATQITVSFAASNRFPVEALEELYAGIQLAAKLYNVDVIGGDTTSSTSG----LMISVTAIGIAEKEEITYRNGAKANDLLVLSGDLGAAYMGLqVLEREKQVFKANPNSQPdldqytylieRQLKPEARqdippLLKELEVQPTSMIDISDGLSSEVIHLCKNSKLGANLFEEKIPLDPAVISVCEEFEIDstmvALSGGEDYELLFTISQDDYDKI-------KGNPHLTVIGHMTEENeGMHLVTR-------------------
>UniRef50_C7R8N3(5-304:323) Thiamine-monophosphate kinase n=1 Tax=Kangiella koreensis DSM 16069 RepID=C7R8N3_KANKD  E=2e-49 s/c=0.66 id=24% cov=47%
----------------ELIKEYFSfsqSKSDTVVEGIGDDCAVLS----VPDKRQLVTSVDTLVDGVHFFsdsDPADIAYKSLAVNVSDLAAMGAKPLGFTLAIALPK-VDEVWLKSFSKGLQEASADFEIPLIGGDTTQGP------LTITVNVLGSVKADKAMLRKSAQLDDDIWVTGYVGDAAAAL---------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C0CMS4(4-326:339) Putative uncharacterized protein n=2 Tax=Clostridiales RepID=C0CMS4_9FIRM  E=6e-49 s/c=0.61 id=25% cov=93%
-----------GKLPEQvLVRSVIKKISHRRDEVLFGPGVGRDCAALKLAKDEIfVISSDPITGTV-----KDIGSHCIYITANDLAAAGAEPVAVMVTALLPPETEEKDLRGIVEDMEKTCAALDMEVIGGHTEVTDT--VKQPLLSVTGVGKMKAGEALYEKKLKAGQDLVVTKWIGLEGTSIVAKERAQKLREVFAESFvrtaqnfdQYLSVLPEsRIAMEHGVSVMHDITEGGVFGALWELAQGADVGLDVDLKKIPIRQETVEVCEQFGLNPYLLMSSGAMLIGT--EQGEILVRKLQ--EAGIPGTVIGQAVEGSSRILRNG-EEIRYLDRPQSDELYKI-
>UniRef50_A1SWW7(7-308:335) Thiamine-monophosphate kinase n=2 Tax=Psychromonas RepID=A1SWW7_PSYIN  E=9e-49 s/c=0.65 id=30% cov=46%
----------------DLIDSYFKRSTtvqnSGVALGIGDDCALLD----IPEGYQLAVSTDSLVCGVHFFEDVDpyrLGYKALAVNLSDLAAMGALPKWVSLAITLPNGAmvnnNPNWLSEFTRGFFALADKFDVVLVGGDTTKGP------LSITVSVKGIVPRGLALQRNKANLGDLICVSNFIGD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5N2W0(4-321:329) HypE n=8 Tax=Clostridium RepID=A5N2W0_CLOK5   E=2e-48 s/c=0.61 id=21% cov=92%
-----------GKLDWKDLKSIIDKNRSVERNDvRVRSGIGEDCSVINFGDKECVVSTD-----PITGANINSGRLAVHINCNDIASCGIEPVGLLVTILLPEGASLEDINRLMGEISDEAKKLNVEILGGHTEV--TSAVNKIVISCTAIGKGDKGKAVSTSGAKEKDDIVATKCLCLEGTSIIVNDYEDKLIGLLtkeeINEAKNYIKQISVVKEgilsgGFGVNSMHDITEGGILGALWEIAEASRVGFKVYKDKLPITKITEKICGHYLIDPLKLISSGSMLITTPKG--EELVRMLENE--GIKACVVGEITKGGYKLICN--GEEEEIDAPGRDEL----
>UniRef50_Q6MP56(8-317:318) Thiamine-monophosphate kinase n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MP56_BDEBA  E=2e-48 s/c=0.63 id=22% cov=69%
------------------------------------------------------------------FSAFDLGYKSLAVNLSDIAAMGALPHFAQVSLALPKKLNESWLDDFYKGMTSLADDHHMQVVGGDLAASP----DRLVVDVSVHGSCE--NPLTRKGAKPGDLLLCSGPLGLSFTGMTALQKKLSGFDDAKERHLRPKPRLDLVASLQkqhtRIHALMDCSDGLVNDALQ--LRPPNGGFHLFAENLPLHPDSESLAVDLHLNPqdfvLWGGEDYELLMAVHPEDYEYF----------PEWKMIGQFTEDPRVFV----------------------
>UniRef50_Q65TX9(7-314:331) ThiL protein n=4 Tax=Pasteurellaceae RepID=Q65TX9_MANSM   E=2e-48 s/c=0.63 id=28% cov=45%
----------------DLINRYFALSKQIPRqdviLSIGDDCAITQLKA----DQRLAVTTDTMVENSHFYptiPPRALGYKAVATNLSDLAAMGATPTWVSLALTLPK-TDSHWLNEFSKGMFEILNRYDVTLIGGDTT-----KGEIPTVTITAQGLL-GDYALCRHQAKIGDWIYVSGTLGD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q1IHF6(6-313:318) Thiamine-monophosphate kinase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=Q1IHF6_ACIBL  E=4e-48 s/c=0.63 id=21% cov=85%
---------------RALIERIRRRAssrkFSAITRGIGDDCAVLD----PPPGHELLVTTDFCLENVHFRREWHpakaVGHRCLVRGLSDIAAMGGDPLAAFLSLALPAEIPQKWVDGFFDGLLALAERWKVPLAGGDIAQSPQGVMADIMV----LGSVPRGKAILRSGGKPGDVLYVTGTLGLSVAALQAFRAGKKPTAKSTPRHFFPDPRIDigRLLRERKLATAMIDLSDGLSTDLSHICDESGVGAVVYATSVPY------VGGENGLEfALNGGEDYELLFTANPR------ARVPKEIDGVPVTAIGEIVQRRGMWLEDKRG-----------------
>UniRef50_C8WRZ3(6-305:323) Thiamine-monophosphate kinase n=2 Tax=Alicyclobacillus acidocaldarius RepID=C8WRZ3_ALIAD  E=1e-47 s/c=0.64 id=26% cov=80%
----------------------------------GDDCAVVD------GGGRLAVTTDAVVEGVHFrrdtMSPPQMGYRAMAAAVSDIAAMGGQPAWITVALAVPPSWPQEDVVAIYDGVSEAAAAFGASVVGGDVV----STQGPLWMSITAVGRVE--RPVTRAGARPGDVLFVTGSLGgsAAGLDILLGRRAGSAIAQavLVERHRRPTPRIAFGREAARLgATALDDISDGLASELNEIAEASGVRLLFEGDRVPIQPEVTEYARAVGKDPLEyalfGGEDYELVGTAPRDVFARLLAV--APVVGTPITAIGRVEEGDGVVMR---------------------
>UniRef50_C7NS45(1-330:345) AIR synthase related protein domain protein n=1 Tax=Halorhabdus utahensis DSM 12940 RepID=C7NS45_HALUD  E=3e-47 s/c=0.58 id=27% cov=93%
-----------GKADREFFDEYIYPRLGADRDDvRLQPQHGVDFGVADVGGQALAMATDPVFIVPA-AGFERAAWFAFHILFSDVAVSGLDPAYLSVDFNLPPEITDEQFETVWETFDQEAAELGASIVTGHTGRY-AGCNYPMVGGATTVATGDFDDLVTPDGARPGDRVIVTKGPAIEATGLLSVHFDSLMDGEVPADeiqaakdrFYDMSPIQEAMVASAAgpVTAMHDATEGGVYGGLFEMARSADVGFEIERDRIPVQPGVEAACDFFDIDPWISISEGTLLATVDPDGASDVLSALKSE--GIPAADAGRVVEGSGLTVDG-----QAVDHPGKDP-----
>UniRef50_Q2RKM3(1-331:528) AIR synthase related protein-like n=1 Tax=Moorella thermoacetica ATCC 39073 RepID=Q2RKM3_MOOTA  E=3e-47 s/c=0.58 id=28% cov=84%
------------------VDDAFFRQAILPHTGAGDPEVvvgprmGVDAAVLKIGEEYLAVAEDPIFPGPTTSPD-DFGWITVHIGASDVAVMGIKPRFMTYSLLLPPGTPEDYIAGLVRSISTYARELGITIVGGHTGFY--GAVTIPTIGGiTVWG--RGREVVTPAGARVGDAVIITkGAAIEAAALVACELGEKLLAAGISPDLvARAKKRLREMsvvaeagiaVEVGGVHAMHDATEGGLARGLWEVAEASGVGLRIERARVPVPADIRAVCDYIGLNPYEVISEGTLVLTCAPEKADAMLAAFK--EAGIEAAVIGRVV-----------------------------
>UniRef50_B8GHF5(9-337:345) AIR synthase related protein domain protein n=1 Tax=Methanosphaerula palustris E1-9c RepID=B8GHF5_METPE  E=6e-47 s/c=0.58 id=24% cov=91%
------------------IDAATFASFLLHRTGAADPSvivpptAGIDAGVVDLGNNRVLI----VAEDPIFAipnqPYDLFGWHTVHIGASDVAVMGVKPQYMTYSLLMPPGTPDQDFRTIVDAIDLAAKDLGIAIVGGHTGYYPGFAAPTIG-GITVFAVAEKGEYITSAGARPGDDVLLTKGPAIETAALLSVLRENELKAKYPAWLvkaaqdlcwqMSVVADAALAREAGEVTAMHDATEGGVIGGLFEIAAASNTGMVIDEAQIIYPKEVRMVCEQFNLDPLASIAEGTLLLTADPSSSDAIIDLLTR--SGIPVSVIGKVTDNPGeRTIRRVDGTIEELHIPEQDP-----
>UniRef50_B4U7Q4(6-297:306) Thiamine-monophosphate kinase n=3 Tax=Aquificaceae RepID=B4U7Q4_HYDS0  E=7e-47 s/c=0.65 id=22% cov=79%
-----------------------------------------DTAYIKIGETGLNITCDAFLEDVHFlrhYPPEAIGFKAISINVSDVVANGGKPLYGLISLMIPEDIDERFIERIYEGVKSACDFYKLRIVGGNVS-----KASKLGIDVFLIGEI--DRFVSRAGANVGDDVVVSGTLGDSYTGFRLLttkKEYEDYELRLIERHLRPTARIDYINHIRKYASACMDISDGLSSDLWHIAERSNVVIEIDLNKIPISRELRLYASKENLNPydiaLSGGEDYQLLFCQKKEHFNPFLDN----------TVIGRVIEqGKALVLVNGKELER--------------
>UniRef50_UPI0000E87BC8(6-300:314) Thiamine-monophosphate kinase n=1 Tax=Methylophilales bacterium HTCC2181 RepID=UPI0000E87BC8  E=7e-47 s/c=0.64 id=20% cov=86%
----------------SLINKYFNQKSSTAPLGIGDDGALLE----KNSQNYYVLSQDTLNVDSHFFRDTNIkylGWKTLAVNVSDILAMGGNPKFALLSISTEEA-NDSWLKKFSSGLFDCANQYGVELIGGDTSRGS------LSVTITIIGEVKKKYVLRRDGANAEEDIWISGELGLASLGFAHQIKTLSLPGHISKKALLalhkPTPIIIDMSKINHLFTSAIDISDGLVPDIQHILNKSNIGADIFCEHLPVPLWIK---ENDGYDfALYGGEDYQLALTSPKSNRKKIEKI--AAQNNLQLSVIGKTNTSKALKLYDVNG-----------------
>UniRef50_B6YTL7(1-304:311) Thiamine monophosphate kinase n=2 Tax=Thermococcus RepID=B6YTL7_THEON  E=8e-47 s/c=0.62 id=22% cov=88%
--------------MEREIIELFMKYLK----KQGDLPLGDDAGALRIGDEWLVATNDMLVgktDVPDIMTPEQVGFKAVTMNVSDIAAMGARPIGFLFSLGVPRGFDGLYLEGVAKGIGNALEFYEIPVLSADT-----NEADDLIIDGIALGRTRH--LLTRSGAKPGDLVCITGDIGRPLAGLLVWKNDLDVslstKEILYEKLLEPRARVKEGIKIGNYANAAIDISDGLAKELHLVAEMSGVRIEVDASKLPIMEEVFEVAELLRRDPLEialaSGEEFELVFTIPPKYTEEL---------SFDFTVIGTVHKGAGVFITT--EEKRMEVPPIG-------
>UniRef50_B4RQH6(5-311:318) Thiamine monophosphate kinase n=28 Tax=Neisseriaceae RepID=B4RQH6_NEIG2  E=1e-46 s/c=0.62 id=23% cov=85%
---------------------------KDVVLGIGDDAAI----VRPREGFDLCFSADMLLKDRHFFAdvkPEGLAWKVLAVNISDMAAMGAIPRWVLLSAALPE-LDEVWLERFCGSFFGLAKKFGVTLIGGDTTKGD------MAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRVGMAAAALNCRLKRCVLPDDVFAECeqklLRPEPRVGLGLALLPFARAAQDVSDGLAQDLGHILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTlaGGDDYELVFTAPESCRSRVLDA--AERCGVPVTCIGKI--NGGCRLKVLDAGGRELELHS--------
>UniRef50_C6VU01(19-331:340) Thiamine-monophosphate kinase n=25 Tax=Bacteria RepID=C6VU01_DYAFD   E=1e-46 s/c=0.60 id=22% cov=86%
------------------INKGIRPALPDTVRGIGDDAAVIDLGEELG-----LLTSDMFLEGIHfdltFFPLKHLGYKIIAAGVSDIAAMNGIPRQVTVNLALSNRFSVEAVDELYEGMKVACKDFNVDLVGGDTTSSRSG----LIISVSAFGKVKKDKIAYRNTAQPNDLLCVTGDLGGAYMGLQLLEREKqvflanpNMQPELEGKDYVIQRQLRpearmdvvyELDEAGVIPTSMIDLSDGLASDLLHICAQSGVGAVIFEERLPIDEQTYLAASELNIgaatAALNGGEDYELLFTVSQSAYEQI-------KNNPKITFIGYITDKKGEVELHTKGDTRV-------------
>UniRef50_A1AW74(5-289:309) Thiamine-monophosphate kinase n=2 Tax=sulfur-oxidizing symbionts RepID=A1AW74_RUTMC  E=4e-46 s/c=0.66 id=20% cov=65%
------------------------------NLGIGDDCAVID----IDANYQLVTSVDTFIEGVHFpsnTSASDIAYKSLAVNLSDLAAVGARVKYFTLALTLP-NINKKWLSQFSTSLKSLADEFGIVLVGGDTT------KGMLSITINVTGVVKKNKALLRSSAQVGDLIFVSNTIGDAAYAWKQLQNNQTPSEYVINQFNRPKPQLFLGQQLSDIANACIDISDGLEQDLTHILTRSNVGASINLDDIPLTYEVKTYIE----------------------------------------------------------------------------
>UniRef50_C6X363(34-335:364) Thiamine-monophosphate kinase n=6 Tax=Bacteroidetes RepID=C6X363_FLAB3  E=5e-46 s/c=0.62 id=22% cov=72%
-----------------LIKHLTEKFgFDNPSTET---SIGDDAAVIDPQNQKVVITTDILAEGVHFnlgyVPLKHLGYKAVVVNLSDLAAMNAIPTQILVGLAVSNRFPVEALEEIYEGIALACKRYKVDLVGGDTTSSTSG----LVMGITAIGLEQSENLIKRSGAKPNDLLVVTGDLGGAYLGLqILEREHsvylanpnmqpemEGYDYILERQLKPEarTDIKKTLKELDIQPTSMIDVSDGLSSEILHLADQSKVGFRLYEEKIPMDSLTISTAEELNLNP----------------------------------------------------------------------
>UniRef50_B3QYZ8(21-344:373) Thiamine-monophosphate kinase n=1 Tax=Chloroherpeton thalassium ATCC 35110 RepID=B3QYZ8_CHLT3  E=5e-46 s/c=0.58 id=24% cov=79%
----------------------------------GDDCAILEFS----DTEYQVVTTDLLIEQIHFdlltTPMEHLGAKAISVNVSDICAMNALPTYAVVSIALSEKLSVEMVESLYKGMSNAAKEYGLAIVGGDTSASTAG----LVISVTIVGKVKKEKVARRSTAKPGDVVCVSGVLGGSHAGLKvLMRERKLMLDNLKEDgsvdenyrpeiadyqdavsrhllPKARLDIVRLFERRGIVPTAMIDISDGLASEIKHICKESKTGAIIEENKFPIMSHARHVADEFEEEattyALYGGEDYELLFTLSPEDAEKLQET-------DDVKIIGEIKPEAyGVVM----------------------
>UniRef50_C0GCU5(9-327:335) Thiamine-monophosphate kinase n=1 Tax=Dethiobacter alkaliphilus AHT 1 RepID=C0GCU5_9FIRM  E=6e-46 s/c=0.59 id=22% cov=89%
---------------RALI-KQITEVLGESASANGFVGIGDDAALTTCNKEAWLVTSkDMLVEGVHFLlpamTPADLGYKALAVNISDIAAMGGVPRHAYVALALPKETGVEFILEFYRGMGPLAAELGTTISGGDTVSSPG----PLMISITVQGEVDRQKALLRSGASPGDILCTTGPlGASAAGLALLLNRELDCPEKLRSQALnahfRPVPRVREAdfLAHSGAVTAAMDISDGLLEDLGEISQASGCGVLLEEDKIPVHPAAQQIAPLaqsLAAEWaLNGGEDYELLLAVQSRRFASLSREYES-RFGVPLMPIGKVVGEKGLWMVTKEG-----------------
>UniRef50_Q2RJB8(11-328:337) Thiamine-monophosphate kinase n=1 Tax=Moorella thermoacetica ATCC 39073 RepID=Q2RJB8_MOOTA  E=7e-46 s/c=0.59 id=25% cov=90%
-----------------LIERLKAGAIVDParvVMGIGDDAAVLKG----EPGFLTLASTDMLVEDIHFtlatATPREIGYKTMAVNVSDIAAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFGVNIIGGDTVSSPR----AMVINLAILGRVENDACLYRHGAQPGDILLVTGDLGGSAAGLDTLLSPRPAPAEViawaRARHFRPTPRVVEIRAAlkAGGLTAADDISDGLVAEVYTLATASRVGIVLEAGAIPIAPATRQLAAIYHKEPldyaLYGGEDFELLLACRPDKVDAVREAVNRACR-TPVTVIGRVVPAEEGITINHSG--RVLPLTPG-------
>UniRef50_Q97BE7(32-362:374) Hydrogenase expression formation protein HypE n=3 Tax=Thermoplasma RepID=Q97BE7_THEVO  E=8e-46 s/c=0.56 id=21% cov=93%
-----------GKLDRKFFTESILRYTGY---RRPEDKVppknGVDTGIISIGNGKvMAVTTDPFYFDPVF-GYEDSAWFAYHILASDITTAGVYPEYMTVDLNLPISISNEEIARMWKTVHEEAYKYKTSIITGHTARY-ANTGFPMVGGATMFGFTDDDKYVTTAMARPGDIMIMTKTAGIEAASLLTRIFPNHVKKNLGEDkyrygfelFRKLSTVDEAIQAIefgtrKAITSMHDATEGGLLGAVYEVAEASGNGVSIDKEAIHVDDYVKEIHSLFGIDPLRSISEGTLLMTIDPEYADEFMKRL--TKSGIDSYVIGKmTTKDEGIKFKD---GSEPIGEPEKDP-----
>UniRef50_D2QDU8(12-332:339) Thiamine-monophosphate kinase n=1 Tax=Spirosoma linguale DSM 74 RepID=D2QDU8_9SPHI  E=8e-46 s/c=0.58 id=22% cov=80%
----------------------------------GDDAAVFDWG-----DDYGLLSTDMLVEGIHFdltyVPLKHLGYKAITFGVSDIAAMNGLPVQVTVSIALSSRFPVEAIDELYEGIRAACEAYKVDLVGGDTTASRSG----LIISVSVLGKVPKNLITYRNTAKPNDVVCVTGDLGAAYLGLqllerekqvfladpnmqpnLSEERAYLVQRQLRPDART--DMVHELRDLGIRPTSMIDISDGLASELLHLCHQSGTGAIIFDENIPIDDQTHLAADEFKISPitaaLNGGEDYELLFTVPPQEFEKLSANAR-------ITAIGYLTADPKqIVLATKAG-----------------
>UniRef50_Q0W120(11-300:322) Putative thiamine monophosphate kinase n=2 Tax=Euryarchaeota RepID=Q0W120_UNCMA  E=2e-45 s/c=0.64 id=29% cov=82%
-----------------LIRR-IGKILQSPYL--GDDCAVIDNG-----NDYLVVTTDMLhrvTDFPREMTGEDIGWMSVAVSLSDVAGMGARPVGVVAAIGIPGDTDIEFIDGIATGMRNCAKCYGTDIIGGDTDQHQ-----ELTIVTTAFGRVNKDQVKLRSGAKVGDLLCVTGYLGTTAAGFKVLTGEREASPEdrqilFRSFFRPEPRLGEgmILAQYPGVTAMMDVSD-GLGKSVYELSVASKVGFIVYADALPVREEARKVArsrtELLDM-AICFGGEFELLFTVNPDEVGNI--------KGVDFTVIGKVTE-SGLVLD---------------------
>UniRef50_A4YFC4(5-323:332) AIR synthase related protein domain protein n=3 Tax=Sulfolobaceae RepID=A4YFC4_METS5  E=3e-45 s/c=0.58 id=22% cov=90%
------------------IDRKVFDEVIYPHLGKRLDEVivppltGVDTGAIDLGDRVLVVKTDPVFIVPQFGMKKAS-WFAVHILASDVMTSGIPPRYALLDLNLPPSMTDEEFREMWVGIHEALLEIGVMVVGGHTGRYE--GVNYPMVGGfTMIGIGEKEKLGHPSKVKPGDYVIVTKGPAIEATGLLTNLYPEFFRERMRSDLFKEaldmywkmsCWKDGLIASQVGIHMMHDATEGGLWNALVEISEVTGKRINLVGERLFINPAVREVTRIVGIDPFSSISEGTMVIVTDKEKVKE--ELLRN---GIEAEIVGRVESGEGVYVDG-----KRIEKPSEDPFWR--
>UniRef50_Q1Q1A8(40-336:340) Similar to thiamine monophosphate kinase n=1 Tax=Candidatus Kuenenia stuttgartiensis RepID=Q1Q1A8_9BACT  E=5e-45 s/c=0.62 id=25% cov=71%
-----------------------------------------------------------------------VGRKAIACSISDIASMGCKPSVAVISLCFPHGTKNSFAKRLYAGIWEIADKYDIDIVGGDIISGEG----PFCINVTLLGKNEGLMPVYRSGAKAGDKILVTGRLGGSLLG-----KHMFFEPRL--------DEGIALNKNFTVHAMIDISD-GLTADLNHILEESGVGAVLFEDKIPVSDDALKISKKTGKTPihhaFSDGEDYELLAVLSKTQAEKVLTSDLFH--GLEISCIGEIVEDKGLWLRDGKGKLRRI-RPKG-------
>UniRef50_B5Y6B6(31-314:339) Hydrogenase expression/formation protein HypE n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y6B6_COPPD  E=6e-45 s/c=0.64 id=25% cov=72%
----------------------------------------------------------------------GIGWLAVHVACNDIAASGIKPRWVQLLVMLPSLDQPEELKQIMSDAARAADSLNVTIIGGHTEA--SNGLRRPLVAATALAPACGKRVVRTSGAKPGDIIYVTRGVGLEGTGILAsdfaveARKRGLTDQDLNEALKLLSsvSVVSEALKLAdlGATAMHDVTRGGILETLLEIASCSGVCMEVDRSRIPVPEVVKRFANAFEFDPLKMISSGTLVATLPPEMCETAEALFENQPC--KLFRIGVVTEGRGVLLR---------------------
>UniRef50_Q1NMW0(31-317:337) Thiamine-monophosphate kinase n=2 Tax=delta proteobacterium MLMS-1 RepID=Q1NMW0_9DELT  E=7e-45 s/c=0.64 id=25% cov=52%
------------------------------------------------------------------------GRKAVTVNISDIAAMGGTPRFVLLSLGLTGREEAAWREELLAGLVEATAAYGAHLIGGDTVHSPG----RVMLTVTVLGEVAEAELCRRDGGRQGDSLWVSGPLGWAAAGLELCRRGLGTEERWQPLVkAHLNPdaqvaLGRALARGRLVHAMQDLSD-GLATDLAHLAAASGQGAEVKAELLP--------------------------------------------------------------------------------------
>UniRef50_A8MDD6(3-309:337) AIR synthase related protein domain protein n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8MDD6_CALMQ  E=1e-44 s/c=0.59 id=23% cov=88%
------------KFSNAFIEREVFKMLGvRDNSVTLGPGIGEDAAVIRINNSYMAVHTDPVTGSSNL-----LGWLAVHVAANDIATRGIRPRWFLVTLILPVDYGENDVVNIMRQINDALIEINASLVGGHTEKSD--AVTRPIAVTTAIGI--GSRFIRTGGLRTGDVIVMTKYAALEATAVLVSDFRGRLmnvlsEGEFKeatSLYRMVSVVNDALAAAEYATSMHDPTEGGVLQGLLEMAYSSGKLIIINEDNIPVLPVTRRVLNAFNLNPLTVLSSGSLLIGVGENDAAKLIGKLR--DMGINASIIGKVTDGePGVVVKGRSG-----------------
>UniRef50_A3DLS7(22-345:355) AIR synthase related protein domain protein n=1 Tax=Staphylothermus marinus F1 RepID=A3DLS7_STAMF  E=1e-44 s/c=0.56 id=21% cov=93%
----------GGKPSWEFLSEMLSILPTMDPDLIVGPSIGEDAAIIRFKDGFLIVHSDPITA-----ATRRIGWLAVHIVANDIAVRGATPRWFLPVILLPPKYPVEQIESIFEDIGLATRSLGATVIGGHTEFTP--GIPRPIISMTAIGYSMDKVVLTR-NARPGDKIFIIGRVGGEGASVIAWDFEdlllrKGISRDIIAKAKEYFTGIsvvdKALLIRDYVNSMHDPTEGGLLQGLREVAKASNTRIILDADKIILDPVVKEITSALKLDPLKILSSGVLIASVPKENTRQVEDLLQEKEYKYSiAGYISEYVKGGELIVEQNGKTIRIIEDVVDEI-----
>UniRef50_C9LRA0(17-317:329) Thiamine-phosphate kinase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LRA0_9FIRM  E=2e-44 s/c=0.60 id=22% cov=80%
-------------------------------LGTGDDGAVF----MTPCGYDEVISTDTMVEGIHFtkrtMSAADTGYHLCAVNFSDMAAMGAEPVSFVISAALPGDLSITWIESCYDGIRECCREYSVNLLGGDIT----GSKQGVILTGTIVGIVPENQAVKRSGAKEGDIVFVTGTLGDSSAGLSiLLDGKKEEYPMLAIRHQRPKPQIDfgRILRESGASSLNDVSD-GLSREINEITSASRVTIELEKERIPLSDELCRWGRDCGKDPFcfaiNGGEDYELVGTISKKNWEYIKDI-------DGVTGIGHVTKagKGQVFLK---------------------
>UniRef50_A8VUM5(19-320:332) Beta-lactamase domain protein n=1 Tax=Bacillus selenitireducens MLS10 RepID=A8VUM5_9BACI  E=2e-44 s/c=0.60 id=24% cov=54%
----------------------------------------------------------------------DIGYKALAVNISDLAAMGAVPKQYLVSLAVPKqGWPDEETRRIYAGLEEAAALYGMDLIGGDTV----STADKLVISVTVTGIVETSVRLLRANARPGDVIAVTGPLGASLAGLDLLLDqtngvpvpEMDQDQLIRSHQRPVPQVkAGRLFAELGIRAALNDISDGISREAKEIAEASGVRMVLDWKRIPKPD-----------------------------------------------------------------------------------
>UniRef50_D1A2J3(36-344:352) AIR synthase related protein n=1 Tax=Thermomonospora curvata DSM 43183 RepID=D1A2J3_THECD  E=2e-44 s/c=0.59 id=23% cov=71%
---------------------------------------------------------------------------------SDIAAMGAQPIALLSVVRYPKTMPDERFAQVLQGINDACARVGAPNVGGDI-----GTAERLILSASAVGVVEAGRSLLRGGARPGDRLCITGPTGVAAAAqkyfgkldVADTRLSPQAEELLLNAWKRPQALVPEGRSLstSGLVTSCQDSSDGLKAGIESIAARSGVGFTVEEDALPVVGAVEEVAKLSDTEltPLLLGDsvDFQLIFTVPEEHVEELQEIFAAHGHSA-FHDIGFATEEPDLLLRGSDGITRRLP-----------
>UniRef50_D0MD26(16-338:358) Thiamine-monophosphate kinase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MD26_RHOM4  E=3e-44 s/c=0.56 id=25% cov=88%
-----------------LIDRLqtIVADLSDPDLimGIGDDAAVYR---LPDEETVHVITTDALLEGVHFdrlmTPMEHLGYKAIAVNVSDVVAMNAEPRYATIAVGIPAKISVEMMEAFYRGVRRACEKYGLVLVGGDTT-----AAHTLCISVTVVGEARMEDVIFRRGARPGDLLCVSGDLGAAYAGLKILleqrRALKEKGADYQPDLEPYRYVIqRQLLPEARLDVIRDwrdrgvrpraliDVSDGLASEVHHLCRHSNCGAIVYASAIPVALETREVADHFAEDvdtyALFGGEDYELLFALPPEQ----LELLDPTSFN----VIGEFLPaDQGVQVQTPEGAIIPLEP----------
>UniRef50_C6V4B8(16-306:313) Thiamine-monophosphate kinase n=2 Tax=Neorickettsia RepID=C6V4B8_NEORI  E=3e-44 s/c=0.62 id=22% cov=83%
---------------HRILSEIISRIAEPFSL--LNDAFVLDD---------FVITKDLLVESIHFFPfaePRNLAKKALRVNLSDLAAMGAEPVGYFLGLVLGEKHkSSTWLNRFAEGLLDDQHCYGIKLFGGDTVIHSG----PLLISVTMIGK-KAEHVLSRSGAKRGDELCISGPIGDSHLGLLSYQGELQENSYFRGKYDLPEPCLDVSRDIISSVTSCIDISDGLLSEAQHLAKNSAVSITIFFDKVPISDEAKSVLlkkPEIRKELLTAGDDYQLLFTVPREN-----------PVTRKYPVIGFVSEGMGeVRVLDSFG-----------------
>UniRef50_C0QQC1(11-312:317) Thiamine-monophosphate kinase n=2 Tax=Hydrogenothermaceae RepID=C0QQC1_PERMH  E=4e-44 s/c=0.60 id=18% cov=80%
-------------------------------------GFGDDCACVNLDGKLMLFTGDIQLENHHFIKGkikpEDLGWKLVSINVSDIVACGGKPRWGFISIGIPESTEYSFIEGVYKGMNDALDRYGFSVIGGNTT-----SSEEIILDLFLVG--ETERFVPRGGAEEGEVILLSGFTGcsRAGLELLLMDREsyEDFEMRLIEKHTRPEARYDLQNLIQRYARSCIDISDGLVGDLSHIQKMSGVKLVIEKDKLPVDPDLERFCKKYGKDiydyILYGGEDYQLVFTVNKQDTEKFKDCFK----------IGYTEKGSGIFIKDEKGLK---------------
>UniRef50_Q54757(27-313:327) Thiamine-monophosphate kinase n=9 Tax=Cyanobacteria RepID=THIL_SYNE7  E=6e-44 s/c=0.63 id=20% cov=69%
-----------------------------------------------------------------------IGWRAAAANLSDLAAMGATPAGITLALALPSDRRLSWLQQIYQGLDRCLKQYDCPLIGGDLSRSPTA-----TLAVTALGWVNPNRVIRRSTAQVGDWIMATGTHGLSRLGLGHLLGEWTLAEPLRdqaiAAHQAPKPRLDVVPLLARSqpagtvwRVAGMDSSDGLADAVLQICRASQVGAVI--EALPLPATTSFDRDRLIQAALYGGEDFELVLCLSPDWAQALLELL-----GEQAQVIGQITEKPVVQLR---------------------
>UniRef50_Q1QUD0(6-300:319) Thiamine-monophosphate kinase n=1 Tax=Chromohalobacter salexigens DSM 3043 RepID=Q1QUD0_CHRSD  E=8e-44 s/c=0.61 id=25% cov=69%
----------------DIIARYFTTPDSEPPMPGVALGVGDDCALLSPEaGHELALSVDTSVVDVHFpgdAPPEAIGHRALAVALSDLAAMGARPRGCLMALTLSHAEP-DWLERFAHGFRELGRRTATPLIGGDVTRGS------LSIGVTVIGDVPAGQALRRTGAAPGERLAVTGSLGGGHAGLRMWQaGGHDLADPLLAAYLTPTPQLAAGQALRDLASAGLDISDGLLADLGHLCRASGVGAVLSPDDLPLAPS----------------------------------------------------------------------------------
>UniRef50_B2V6K1(1-304:314) Thiamine-monophosphate kinase n=3 Tax=Aquificales RepID=B2V6K1_SULSY  E=8e-44 s/c=0.59 id=19% cov=85%
-----------------LIERLnqILPIHDKDVLVGYGD----DCACVNINGKLILFTVDIQVENSHFLKGkikpEDLGWKLATSNVSDVVACGGLPRWALLSLALPKDLEYSFIEKVYLGIKEAQDYYGFYTIGGNCS-----SSNQIMIDMTMAG--ETEKFISRSAAKPNQKIYLSGNLGCSKAGleliLMDKQEYEDFEIALINKHYRPKARIDLIEKIKQASACIDISD-GLTSDLSHISKKSNVKIIIEKEKLKIDENLKKFCLKYGKDPLD------YILTSGEEYEVALIS-----EKDLDLIEIGYTEEGFGVFLK---EGDKIVEL----------
>UniRef50_B6BWK7(5-296:316) Thiamine-monophosphate kinase n=1 Tax=beta proteobacterium KB13 RepID=B6BWK7_9PROT  E=5e-43 s/c=0.61 id=24% cov=33%
----------------DLIKKYFNFTSKHALLGIGDDAALIPLN----NNEFMAISMDTLNIGHHFTEDSDpyyLGWKSLAVNVSDIVSMGGQPRYALLSISL-KNLDVNWIGKFTKGIKACAKKYNIEIVGGDT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0APG5(38-308:320) Thiamine-monophosphate kinase n=1 Tax=Maricaulis maris MCS10 RepID=Q0APG5_MARMM  E=8e-43 s/c=0.65 id=23% cov=68%
--------------------------------------------------------------------------------LSDLAAMGARPRGYLSAIAWPEALDAAWREAFVRALHREQSRYGLVLIGGDTTSTPG----PLTVTLTLVGQIETGTALRRSGARPGEDVWVSGMIGDGLLGLLSARKAGTELAGALERYQAPDPRLELGLALRGLASAAIDVSDGLLADAGHIAAASACSLRVDVDTVPVSPTARDWLESGGaLDAlLAGGDDYELLFTAPAGCRERIAAL--GLSLDTNLTRIGSVMAGEGV------------------------
>UniRef50_B6QX74(14-307:338) Thiamine-monophosphate kinase n=1 Tax=Pseudovibrio sp. JE062 RepID=B6QX74_9RHOB  E=1e-42 s/c=0.60 id=23% cov=46%
----------------SLIERYFAPLATNAGAVHLQDDA---AVFTPDTGCDLVVTKDMLMAGVHFFkndPPFEVAQKALGVNLSDLAAKGAEPKGYLLGLGLSKEIGEEWVAEFCRGLKLVQDQFQIDLLGGDTISCPQG----PLLSVTAFGQVPKGQVVRRNEAVAGALLYVTGTIGD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8D6Q8(5-314:331) AIR synthase related protein domain protein n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D6Q8_DESK1  E=2e-42 s/c=0.56 id=21% cov=74%
------------------------------------------------------------------------GYLAVHVASNDIAVRGVTPKWFMPVVLIPRHYSVEEAEELFSDMGKALSEIHGVAIGGHTEVTP--GLDRPIIAMTVIGYTN-GRVISTRDAGEGDYVVVIGRIGGEGAGVIAWDFGDKLLGKVPRDVieharsfiYDVSIVKTALAIKDYVNTMHDATEGGILQALREVASASKKDIVVLDKAFYIDEEVKRITSAVNVDPLRLLSSGCIVATVAPGYLDSLLNELKKH--GIRHSVVGRVTRGEGRVIIKGDSGETI-------------
>UniRef50_A3DPV0(9-316:339) AIR synthase related protein domain protein n=1 Tax=Staphylothermus marinus F1 RepID=A3DPV0_STAMF  E=2e-42 s/c=0.57 id=19% cov=88%
--------GELGEEgvLEKIISKYIHKPLPGEYLDYPDDA-----RDILPISPRILVNIDGYSISSMKLPwrtWSDVGYVAVAGAISDQIAKGAVPRDIMVSLGLPPSMEASIVEEIYKGIDEASRDYNLRLLGGDT-----NSSSTPWISVAVIGYTTAKKPPSRKNAKPGDIVVVTSLYGAMGYVAINGVENAIHKEWVVEATKRPRPFLETAIviasNYRGVHASIDVSD-GLGYALKELSKRSNVRIIL-EDKPLYYKELEEICNGntrcLWKYVLNGGEEYGVILTIDPRLSDMIIDYMKKFR--IPHKIIGRVEQGHGLVFEKE-------------------
>UniRef50_Q3ARA0(4-337:369) Thiamine-monophosphate kinase n=11 Tax=Chlorobiaceae RepID=Q3ARA0_CHLCH  E=5e-42 s/c=0.52 id=22% cov=77%
-----------------------------------------------------VATTDLLVESVHFdlltTPLSHLGSKAISVNVSDICAMNALPRYALVSLALPPTFSKKMVEELYGGMVHAAQAYGIAIAGGDTSASRSG----LMISITAIGEALPTQLTRRSGAQLDDLLCVTGTLGGSMAGLKLLMREKeimlehlrnnepvnrnllaDLDEYRELMQRHLLPtarldVVRLFHRLGIQPTAMIDISDGLSSEVQHICRHSNCGALLHESRIPIHATTRQLADEMQEEPltwaLTGGEEYQLLFTLPEATYQQL-----AHERDI--HVIGTITPTNEGMVLEEMFGIRI-------------
>UniRef50_D2RZQ8(7-335:346) AIR synthase related protein domain protein n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2RZQ8_9EURY  E=5e-42 s/c=0.53 id=25% cov=91%
------------------IDRQFFDRHVAPNLGADRDDVavgpqhGVDFGVLEIGGQALVTATDPVSIMPQ-LGLERAARFALDLVLADVAVSGIPPSHLSICFTLPETMTDDEFATVWKTIHEECVDLGVAVVTGHTARY-SDPSHPWVGAATAMAVGDPDEIVRPDGARPGDRLLLTTGPAVESVGLLSTLFADQLEAALPGDViDDAQDRLEEVycvrdalaaAAAGPVTAMHDVTEGGLAGALNEMADGAGARFSVDRDAVPMRPGVQEVCDHLEIDPWAATSSGSLLLAVAPEGVDDVVAAL--EDRDTVVAEIGRVeepsgTDGDGEVVVDGD----RLPHPSVDP-----
>UniRef50_A5UMR0(27-296:306) Thiamine monphosphate kinase, ThiL n=3 Tax=Methanobrevibacter smithii RepID=A5UMR0_METS3  E=2e-41 s/c=0.64 id=17% cov=66%
--------------------------------------------------------------------------------VSDLAAMGATPLGFLLSIALPKDFEVDDFKQIIKGVLKACEYYGICLIGGDT-----NEASEIIISGTALGLC--DNPLMKNTSEKGDLVVLTGKIGLAALGFNLENDNIYTKKALE----PIAKIKEGINIKNSGGTSATDITDGLASELYEMKRE-DIGFMIYEDKLDISGEFKSLAAElnlnYLDLLLHVGEDFELVFTINKKNL---------HKLNFKYLVIGEVTDSKKVEIRLSDSTVR--------------
>UniRef50_Q6L0S9(4-303:315) Thiamine-monophosphate kinase n=1 Tax=Picrophilus torridus RepID=Q6L0S9_PICTO  E=3e-40 s/c=0.56 id=15% cov=87%
---------------SELGERLIIKELEPEP--------GDDCSLIESGNSYYLISSDLITRKTHIPDGASydlAGKFFATINLSDIAAMAGRPIGIMVSYSVNPDLDIRDLKAFHDGIKKQMNRFNAKILGGDTK-----EGEDFTVSGTIIGIQEGSLVRRRSDIKPGQKVYVTNDIGRSSSGFLFYKNNYKRDLGISLMMNVEPRINEAIKISQSGAMFMMDLSDGLAASFYQIRNDYKTGFKIYYERIPKSMYVREASKISGVDekeiILSGGGDYELLFSVPYDTSEAFERSMSLN--NINVSCIGETYDGANIInMDGSWEELR--------------
>UniRef50_C8WEQ3(16-303:321) Thiamine-monophosphate kinase n=5 Tax=Sphingomonadaceae RepID=C8WEQ3_ZYMMN  E=5e-40 s/c=0.58 id=22% cov=51%
--------------------------------------------------------------------------------LSDLAAKGAKPIGALMGYSL--GPDYKWDQAFLKGLESVCHQYNLPLLGGDTVAVPRHTGH--FSAMTVIGLAPSCGVPDRRAAKEGDELWVTSPIGDAGFGLNLLKQKKNInhsaQEKLVQAYRSPEPRLkEGIWLAPHVHAMADISD-GLLIDAERIANASGLAVRIRLDRVPLSSE----------------------------------------------------------------------------------
>UniRef50_C6CVI9(23-321:349) Thiamine-monophosphate kinase n=1 Tax=Paenibacillus sp. JDR-2 RepID=C6CVI9_PAESJ  E=7e-40 s/c=0.56 id=22% cov=57%
----------------------------------------------------------------------DIGYKALASNVSDIAAMGGVPLQALVSVSVPKQLGPEPMHRLYDGLYACAEQYGVAVIGGDTTSSPQHLVVAVTVTG----AVEAGKALRRSGAKPGDAVVLTGPVGKSAAGlhfLLAQRErgadalaGERAAAQLVQAHRRPSPSVRAgrLLLARGTCHSLNDVSDGLASEAWEIAEASGLVVSLFEKHLPRSGSMAAYAGVAGIDP----------------------------------------------------------------------
>UniRef50_C8X4R7(12-307:329) Thiamine-monophosphate kinase n=1 Tax=Desulfohalobium retbaense DSM 5692 RepID=C8X4R7_DESRD  E=7e-40 s/c=0.56 id=24% cov=70%
-----------------LIDRYFPNTHAHMPLGRGDDCAVLRAPDW------MCLTADMFVEDVHFrrtyFSPEDIGYKALAVNLSDIAGMGARPLGFALNLMATGRESDEFCEGLVSGMADLAREHDLPLVGGDLSRGP-----ALAVAITMWGKSQK-RFLLRRNCQPGDLLFCLGDVGLARCGLSVLERDDEslrwrFPEAVEAHLRPQIRLeqAQTLGEFEQVRGLMDVSD-GLMQDLPRFVGP-GFGVEVFMSESEVHPEVvefaREFAGLPGVE-----------------------------------------------------------------------
>UniRef50_Q6AQZ8(18-337:345) Related to hydrogenase expression/formation protein (HypE) n=1 Tax=Desulfotalea psychrophila RepID=Q6AQZ8_DESPS  E=9e-40 s/c=0.52 id=24% cov=86%
--------------------------------GPGLDAAILQTA----DGRVMAIAEDPIFPAP-GLPLDIMGWFTVHIGASDIAVTGVKPEFMTYTLLLPLGCPEEDARTIISSISRAAEDLGISIVGGHTGWY--GAVTVPTVgGVTVWGTADQDAWISPGGAKDGDLILMTKGPCIEAAALLSIVHHERLQGNIsEEMLATLRARVDQItvvedalhaFKVGGVHAMHDATEGGVQGGLWEMSTSSGLPVMVDFDGVEIPADIVALARELDFDPWQAISEGTLLAAVEPEQVQEVQRVW--ADLGIDSYILGKFDSslKENTVLKN--GQSQPLLEPDSDP-----
>UniRef50_B4W5V8(11-319:329) Thiamine-monophosphate kinase n=3 Tax=Caulobacteraceae RepID=B4W5V8_9CAUL  E=2e-39 s/c=0.53 id=21% cov=88%
----------------ETIERLLRPLAHPEWGRGLADDV---AVLPSRPGYDLVLTKDVIVEGVHFLPDdplETVAKKLLRVNLSDLAAKGSEPFGYLLACCWSDRCGWPEREAFAAGLAQDQALFGVFLMGGDTVRTPGPA----VFSLTALGWVPAGEAVSRAGAQVGDLVFVTGTIGDGLLGLQAAQAKLKLDAErlarLIDHYRTPMPRLDFADVVRNLATAAADVSDGLAADLNHIAKASGVGIALNLSVLPLSAAAQAWFED-RVDPQaaledlaTGGDDYQIVFTAHPRHEET--LRREAERRLLRLTRIGAVTAGEGVAVD--YGGRRI-------------
>UniRef50_B3DWZ3(33-304:319) Thiamine monophosphate kinase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DWZ3_METI4  E=3e-39 s/c=0.60 id=26% cov=64%
---------------EQLLEILLKDFQTN---RPGIVGIGEDCAVVQGRGNDLyyLFKVDATVENVHFeagTPPELIGRKALARALSDIAAMGGEPLYALVGIGISKDQKIEKIKKIYEGIRSLAQAFDLLIIGGETTVSE-----QLFLVVSLWGKTEGYKPVLRSGATDGDGLFVTGVLGGSFQS---------------GHHLVFMPRIKEgkwLANGRWAKAMMDISD-GLAKDLPRMAKASSIGFEIDFDAIPIR------------------------------------------------------------------------------------
>UniRef50_A9BIH4(69-361:727) Phosphoribosylformylglycinamidine synthase 2 n=1 Tax=Petrotoga mobilis SJ95 RepID=PURL_PETMO  E=4e-39 s/c=0.56 id=21% cov=72%
------------------------------------------------------------------------------GIVRDILAMGARPIALLDSLKFGNVFDPKVkniFEGVVSGISDYGNSIGVPTVGGETSFNEIYSTNPL-INVMCVGVANKNHLASSHADGPDKLLVYvgskTGRDGIHGASFASKKlsGKDDRPSVQVGDPFTEKNLIEatlEILKIKGVRACQDMGAAGVLSSTSEMAYKGGVGCELYLDNIPKRQE-----DIEPWEIMLSESQERMLFLVNPGTEKKVEAIC--NKYLIDFAVIGKTISTPHYVVKENSEGKVLADLPI--------
>UniRef50_C2D8D1(7-333:361) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Bacteria RepID=C2D8D1_9ACTN  E=4e-39 s/c=0.50 id=20% cov=91%
MERILMSQNAysqagvdveAGYEAVSRIKKHVHATYRKEVLGDLGGFAGLfSLKDFHFDDPVLVSGTDGVGTKILLAkqlnRLDTVGIDCVAMCVNDVLAQGAEPLFFLDYISVGKNSP-ERMEALVKGVCEGCKQAGAALIGGEMAEMPGlYESDEFDLAGFCVGIAERRALLHKSLVHEGDVLVGLASSGVHSNGFSLVRSILGQSlsqhPELLEPTKIYVKSVLPLVQQGLIHGISHITGGGFVENIPRMLP-SDLCAHIYDGSWEKPAVFSMLQEQGNLEyasMFEYFNMGiGLVLSVGKSDAQKVMDALKTA--GEQVFVIGEVEE----------------------------
>UniRef50_B3T8Q3(3-309:318) Putative AIR synthase related protein, N-terminal domain protein n=1 Tax=uncultured marine crenarchaeote HF4000_APKG6B14 RepID=B3T8Q3_9ARCH  E=6e-39 s/c=0.53 id=17% cov=88%
------------KLSEKKIIELFQNRLGNTNFVP------EDVESFKIGKKRLVAKVDTLVEStdvPPGMKLEDVARKSIVSCVSDFAAKGVKPIFGIVSLTIPKRLSRSNIESLAKGFQRAAGEFKLKILGGDT-----NEGKELVINFSLFGISEK--IVNRKGAKTNHVIITSGPFGYSGAGLSILLKNKNgskkFKAKAKSAVFRPNCRLTFGLKNKNYFSSSMDSSDGLSTTLNEMSTQSKKKFVI--TRMPSENDVFDFASSNGLNAndliFNGGEEYEIVATANTSNLTRIKKYAKKHR--IKLYEIGYVTKGSGVFYKKDGKLIRIKD-----------
>UniRef50_B8KML1(23-337:366) Putative thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium NOR5-3 RepID=B8KML1_9GAMM  E=1e-38 s/c=0.52 id=21% cov=84%
----------------------------------GHDAGVLRESLL--PNERLLVNTDrSGVSKAYTLglaGGECIGDFAVSHAVSDILATGGIPFAVSVAMLLPGSTSVKLVDEIVDGIVEACAEFDVTITGGDTK-----KAEKLSLVVTALGRASEDRLLFRDTPKVGDQLVVSGFLGSMLMGSIIHKRHHKVSELIQKLVdealvrQRPPYRLAMEMGAARIATACTDISDGLPSACRNMVEKSNLGVELFADNIPIHPALESLLKTLSLTPLQLSMAGGdwqFLYCMPKASIASLNRI--SDSCGTPLTVVGEVTGASGVWTRSKCGRRRKV------------
>UniRef50_Q1MQK0(17-320:340) Thiamine monophosphate kinase n=1 Tax=Lawsonia intracellularis PHE/MN1-00 RepID=Q1MQK0_LAWIP  E=1e-38 s/c=0.53 id=25% cov=32%
------------------INKYFPDQSHFITAGRGDDCAILSVTSP------LCISTDMFIENIHFrhsyFSPEDIGWKALAVNLSDIAACGAQPIGFTVGLALPLNTSIDILEGIYSGMSRLAKQFNLPLLGGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6HZ14(4-326:335) Thiamine-monophosphate kinase n=1 Tax=Leptospirillum ferrodiazotrophum RepID=C6HZ14_9BACT  E=2e-38 s/c=0.50 id=25% cov=73%
-----------------------------------------------------------------------VGRRLVAVNVSDIVSKGGRPAFSVVAAGLPPGDPPGRIAEVYRGIAEESRYYGVVVAGGDISRDPGG----MSLVMTLLGWIPPGTFVGRGGLAPGDCLYLVGRPGRARSGLLSLEKDQDetLFSEARAAFRTPRALLREgplLASFPGVVSMTD-TSDGLGRSLWELARASRVTIKVEE--IPVSKEVRKWAEALGENPgelvWTGGEDYDLLVGVSFREEEAFLKWARTdllEGSPEGLFLIGQVGErgDPEIIFGSGTGGK---------------
>UniRef50_UPI0001C41E68(50-412:413) thiamine monphosphate kinase ThiL n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C41E68  E=9e-38 s/c=0.44 id=18% cov=68%
--------------------------------------------------------------------------------VSDLASMGAKNIGFLLNIAIPKDTSLDNFDDLICGIIRACDNYNIPLVGGDT-----NEASEIILSGTAIGQVEKGKALMKHGFKEGDLVSISDHLGYAALGFELLKikeenidkyndiifqinkidptvKDLALFKALKPEAKYEEGRILASHNSQENRISATDITDGLASEFYEILNAdkkyylfnkdteshnpndsndsndlnnqqnnqnntnnqdvideyddsnYSKGIRIYEDKLPVDDEFKQIADVLGIDyldlFLHIGEDFELLFTINKELKSQLENDM-------NFYVIGEITNNNTVEIVLSNG-----------------
>UniRef50_Q18DQ7(15-286:298) Thiamin-phosphate kinase n=10 Tax=Halobacteriaceae RepID=Q18DQ7_HALWD  E=3e-37 s/c=0.58 id=20% cov=59%
-------------------------------------------------------------------------------------------------------FDPDEIDSFIAGAIDVCDAANAQYVGGDL-----DTTSELTIATTALGTVTHPSY--RHGARIGDCICVTGNLGRTAAGLKAFETG---DIAHANELFRFTPRVNTGAALAKHTTAMMDSSDGLARSVHQLASASEVGMSLHWDAIPTHPDVKEYVDDVSTRReltTTVGEDFELVLTLPSSELANA-----RETTSVPLHVIGEVTEsDNGIIID---------------------
>UniRef50_B9LTA0(3-327:330) AIR synthase related protein domain protein n=4 Tax=Halobacteriaceae RepID=B9LTA0_HALLT  E=8e-37 s/c=0.48 id=28% cov=92%
-----------GKLGPDALAEVLAATGADDAAVDMGPAYGEDAAAIDLAGTE---STLVVAADPLSLAADAVGELAVHVACNDVAASGADPRWLTHTLFLPDD-DATRRRTVTQQVDATARDLGVAIVGGHTEVLPS--LERPLCSMTALGTT--DRFVSSGGAEPGDRLLLTKGAGIEATAILATDFREACAEAGVS-AATLDAAAGFLDEVSVVpdaaavrdaaTAMHDPTEGGLLTALVETASASGTVLSVERDRVPVRPETRACCDALGVDPLATFGSGALLAAVPPERVDAVTDALAAA--GIDVGEIGEVravddsegSDDGHLLLD----GDRIDEAPRDELYP---
>UniRef50_D1B5R8(3-304:326) AIR synthase related protein n=3 Tax=Synergistaceae RepID=D1B5R8_THEAS  E=1e-36 s/c=0.52 id=24% cov=78%
--------------------------------------VGEDAAVIKwPGDRYLIFTSDPIVGAV-----KGAGRLLVRVNANDVAAKGGEPMFLAVTMIIPPSMGVEAASAIMEEIHRECCRIGVAVAGGHTEFNDRY--DSPVLMGAMIGSA--QRVLSASEVRPGHLVLVTKHLGIEGMSILAHDREDLLGflsgeelEEVRSWGELTSVVPEAALLRDLASFMHDPTEGGFLGGLGEVESLTGLKVRLEGD-LPIHPLTRRAASQLGFDPTCLISSGSLLAFLPPKGLEEAERRL--HRAGIPWSVVGEVLDEP--------------------------
>UniRef50_D2R1W0(3-295:306) Thiamine-monophosphate kinase n=1 Tax=Pirellula staleyi DSM 6068 RepID=D2R1W0_9PLAN  E=1e-36 s/c=0.53 id=23% cov=82%
---------------QQIVSAIKHRVLPHPALvvGIGDDAAI----TRVTPGKQLVTTTDMLMDGVDFLLASTdpvlVGRKSLAVNLSDLAAMAAVPVGAVISLALPRQGGEQLVRQLFDGILPLAAEFQLAIAGGDTNSWDG----PLAISITVWGEVEPGEAWLRSTARVGDKLHVTGALG---GSILERQFTFT----------PRVNEAQQLRRSAQVTAAMDISD-GLLIDLARLCEASQCGAVLDLDKIPVHADAVRLslqehptatpdeLQAFALEhALADGEDFELLLTIAPSD-------------PLAAQSIGEITSARGIFARAADGSLRAL------------
>UniRef50_A8ABX6(42-347:713) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Thermoprotei RepID=PURL_IGNH4  E=2e-36 s/c=0.51 id=23% cov=85%
---------------------------DSPWVVKGGDAAVVDFGSV-----YVAFRIESHN-HPSAVDPYNGAATGVGGIIRDILSSGAKPIALLDDLIfgdLDENLVKWHVKGVVKGISDYGNRVGVPTVGGETWFDPDFTRN-PMVSVACVGVCPKDKLING-TPRPGDLIVIagnyTGKDGLLGSSFASKNLEEGVEEEY-AAIQVPDPLMEKLLidsilemrDERLLVFVKDLGGGGLATALSEVAASFGLGVEARLDALHLREPMEA------WEIVVSESQERMMLVIRPEDLERAKKVLEK--YDVPYSVIGKFTDTGRVVL--YYNGEKVADLPAK-------
>UniRef50_B6WXC8(16-332:349) Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC 29098 RepID=B6WXC8_9DELT  E=2e-36 s/c=0.49 id=21% cov=83%
------------------LARHFPATHPSLLLGRGDDCAVLKA------GTPLCVSSDLFLEDVHFrrsyFTPEEIGHKALAVNVSDIAACGGRPLAFTLALGLPDDVDAAWLDRFFSGMAALAQEQRLALAGGDLSRSPF-----LHVSITIWGESyTGGDFLVRGGSMPGDSLFVVGRPGLArvGLQVLEKEGRAALEHWPAACAAHLLPVpqvdAGLMLARAGANArppALMDLSDGIMRDLPRLlgrtgesrarregdtgtATDSGLGAAILLPQGMLHPEVVRHARENGLNPvheaLLGGEDYALLGSCAPD----MLPILHAAIPGFMS--IGTITDDGELT-----------------------
>UniRef50_B1I654(16-312:319) Selenide, water dikinase n=1 Tax=Candidatus Desulforudis audaxviator MP104C RepID=B1I654_DESAP  E=2e-36 s/c=0.52 id=25% cov=60%
-------------------------------------------------------------------------------------------------------IPLGILEDILRGGADKAAEAGVSIAGGH-SITDHAPKYGLCVT----GFAHPERLVFRSGARAGDVLVLTKPLGTGVIATGIDRRlvDAGLETLAVRYMTALNREAAEVMLRIGVHACTDVTGFGLLGHLWEMAAASGVGVEVEASRVPVIPGALELAragavaggahgnyryarERYRWEPSLSEEMrlvlcdpqtsGGLLMAVAPDKLDALLAALRGAAGAEESAVIGRLVRDP--------------------------
>UniRef50_Q60337(8-305:319) Probable thiamine-monophosphate kinase n=9 Tax=Methanococcales RepID=THIL_METJA  E=3e-36 s/c=0.52 id=21% cov=70%
----------------EIIKKTLKFSNENIVKGIDDDCAIIK----IDENFYLVATTDMMVKKahiPSILSPYEIGGRILTANVSDIASMGAKPLAFLVSISLSkEEANEKFIKELYSGLDDFSKLYDCPVVGGDT-----NRGDELILSGTAFGITDNPIYRRG---KVGDDICVTNDLGRVYCALTLyymLKENKISYKEFERLCQKYPKIIEKLR-----KPIARIKEGLLMNKLiNGCCDISdGLGkeityfknFEIYSDRIFklIPEDVIEFCDAFNLNP----------------------------------------------------------------------
>UniRef50_A3EPZ4(3-303:335) Thiamine-monophosphate kinase n=2 Tax=Leptospirillum sp. Group II RepID=A3EPZ4_9BACT  E=4e-36 s/c=0.51 id=21% cov=48%
--------------------------------------------------------------------------------LSDVYVKGGTPVSALVALGIPKNFPEERIFSFYEGLADACRRFDCPVVGGDISRATGGFDAVLSL----LARSPAGRFPGRDGLLPGDMLYLLGRPGLAKAGYSALLSGLSdhqaMAESVSAFCRPRtYPWFSELVNAEDQVVATMDTSDGLGQAIFAMADQSGVSVRLD-------------------------------------------------------------------------------------------
>UniRef50_B8GHC5(4-281:291) Thiamine-monophosphate kinase n=1 Tax=Methanosphaerula palustris E1-9c RepID=B8GHC5_METPE  E=4e-36 s/c=0.55 id=24% cov=68%
-----------------------------------------------------------------------IGWMSAAVTISDIASMGATPCWLLLAAGLDRG---ERLAGITAGAYACCERFGCRLVGGDT-----DHHEELTVVTTGIGAVMPDRVVRRQGSRAGDLICMTGVPGEAEAGLHGFKQHWYTLIEPQPRVAEGQAIGRAG------ASAMMDVSDGLALSLYDLQTANpSVGYTIRSRLLRRPAGVP-PAEGLEL-ALFGGGDFELLFTCAQD---------RYPIAGVDATVIGAVTDQPGVLLDGEVLEKR--------------
>UniRef50_Q9UY56(16-331:334) Phosphoribosylformylglycinamidine cyclo-ligase n=4 Tax=Thermococcaceae RepID=PUR5_PYRAB  E=1e-35 s/c=0.48 id=22% cov=74%
---------------------------------------GHYAALLDFGNFYLAMTTDGVGTKVLVAEAvgkfDTIGIDMIAMNVNDLLCVGAEPLALVDYFAVKEP-NEEVFKQVAKGLYKGAEEAGVAIVGGETAVMP-DLINGYDLAGTAIGIVEKGKVITGERIRPGDSVIGISSSGIHSNGLTLARkllipkygldyeyEGRKLWEWLLEPTRIYVRPILELINSVEVHGLAHITGGGLLN----LKRLTNYGFELEMPPIEGIFKLIHENGVPLDEMFRVFNMGvGFIVVVPQEEKEEALEILSRH------------------------------------------
>UniRef50_A9A0U4(226-526:539) Thiamine-phosphate pyrophosphorylase n=1 Tax=Desulfococcus oleovorans Hxd3 RepID=A9A0U4_DESOH  E=1e-35 s/c=0.50 id=18% cov=74%
--------------------------------GPGDDAAVLHALKTP------VITTDAQVENVHFSfswqRPGEVGQRAVTVVLSDLAAAYARPVSLFVNLTLPHDRPESLAIDLYAGLKKGLAVYDCALGGGNLS-----GGREVSLNLFAVGEARAPFYPARANARPGDDLYCTGPLGRSRAGLLALAAGLEGYDSLVEAFKFPRARFDAAIVLADYNVrCVMDISDGLAGDARHIARASGITLCFDVDTAVCSDDLQRFCEKTGNRPeemiFSGGEDYELLFACPPETARRIGDVM---------------------------------------------
>UniRef50_B8FWU2(12-334:340) Selenide, water dikinase n=24 Tax=Firmicutes RepID=SELD_DESHD   E=1e-35 s/c=0.47 id=22% cov=82%
-----------------------LPVFQDPQLLVGFDASDDAAVYQINEDTAIVSTVDFFT--PMVEDPRTFGRIAAANALSDVYAMGGSPLFALNLVCYPEREDIQDLGEILAGGAEKLQEAGAVLCGGH-SIYDREPKYGLAVT----GRLNPRQIWKNNTPQPGDRLILTKPLGV-GIVMAALRGEMAEAAAVEAAlasMQRLNKYAAEKARDFPIHACTDITGFGLLAHTREMAGGS-TTIVLYPSALPYiaqaytyaqgylltaagqrNRNFMEGAVEFGDTPFPLQElmldpqtSGGLLLSVPGDCAQEALRAIQETE--PQAALIGEVLPRQ--------------------------
>UniRef50_Q7UA92(59-365:768) Phosphoribosylformylglycinamidine synthase 2 n=8 Tax=Cyanobacteria RepID=PURL_SYNPX  E=2e-35 s/c=0.50 id=22% cov=69%
----------------------------------------------------------------------------VGGILRDIFTMGARPIALLNALRfgpLEDPVNVGLIEGVVAGIAHYGNCVGVPTVGGEVAFDPSYGGNPL-VNAMALGLMETEEIVKSGAQGVGNPVVYvgstTGRDGMGGASFasaeLSADSLDDRPAVQVGDPFLEKGLIEACLEAfsgGDVVAAQDMGAAGLTCSCSEMAAKGGLGVELDLDRVPAREEGMTAYEF-----LLSESQERMLFVVKAGREEALMQRFRR--WGLQAAVVGQVLQEPLVRV----------------------
>UniRef50_Q4L580(15-334:343) Phosphoribosylformylglycinamidine cyclo-ligase n=7 Tax=Bacteria RepID=PUR5_STAHJ  E=2e-35 s/c=0.47 id=19% cov=70%
-----------------------------------------------------------------------IGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVP-EVIEQIVKGVSDGCEETNTALIGGETAEMGEMYHEGEYdLAGFAVGAVEKDDYIDGSAIQEGQAIIGLASNGIHSNGYSLVRKlikesgidlndDFDGRTYLETFLAPtqlYVKPILALKKAVQIKGMNHITGGGFYENIPRGLPE-GLAANIDTQAFPtpnVFNWLQQQANIDTKEMYNVFNMGiGFTVIIDKKDVAQTLDILKQE--GISAFEIGEIIEDK--------------------------
>UniRef50_B4U9Y0(42-349:730) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U9Y0_HYDS0  E=3e-35 s/c=0.49 id=19% cov=78%
-------------------------------------------GVIELEDAWLAFKIESHN-HPSFIDPFNGAATGVGGIIRDIMSMGARPIAILDSLRFGEN-SKRITKGIVKGISHYGNCIGIPTVGGETFFDNCYEKN-PIVNAFCIGVMPKNRIYKARANKVGQILFLigssTGRDGIHGATMASSQfdeKALKKRSNVQiGDPFYGKKLLEAIMyvvENQLVVGIQDLGAGGIAGACFEVAYKSNMGVDINLDEVPLREKDMNAYEI-----LLSESQERMLLIAEKENLQELINV--ANKFHLSWCVLGETTTSNTVNV----------------------
>UniRef50_UPI0001C41B3D(45-349:736) phosphoribosylformylglycinamidine (FGAM) synthase II PurL n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C41B3D  E=6e-35 s/c=0.49 id=20% cov=68%
------------------------------------------------------------------------------GILRDIISMGAMPIALLDSLRfgpLEDQKSRYLFEHVVEGISDYGNRVGVPTVAGEIEFDESFRTNPL-VNVLCAGLVKKDEIVLAVAPNIGDVFLLmggtTGRDGIHGVTFASEELTSDSETEDRPAVQVADPFTKkrvleaslEILEKIDCSGVKDLGGGGLTCCVSELVDKSKNGAVVDLRAIPLREE-----GMTPYEIMLSESQERMIFVINPKDVELAQKICDKHE--IPSAVIGEVTEGSNMVVK---------------------
>UniRef50_B0R2T1(4-325:339) Hydrogenase expression/formation protein n=2 Tax=Halobacterium salinarum RepID=B0R2T1_HALS3  E=8e-35 s/c=0.47 id=25% cov=93%
-----------GKAGRGFFDDHIAGRTGADRDDvRLGPTYGADFGVVAIADSVVAMATDPVFV-LRALGIERAAWFAFHICVSDVALSGLSPAHLAVDLNLPPDTATETFDAIWEVFDREARALGVSLTTGHTGTYEGCSFPTVG-GATALAVGAAEDVVTPTGAQPGDRVVVTKGPAVETTGMLGVLFGDRLPisaaaaaaARDRFADATPVRDAATMAAAGEVTAMHDATERGLANGLHELAAASGVGLSVARDAVPVLPGVRAVCEQFGMDAWAASSEGTVIAAVDPGSVDAVLGALGDE--GIPAADVGVVEAGSGVTVDGD-----PLAEPAADPL----
>UniRef50_Q1JXC5(13-324:326) Selenide, water dikinase n=1 Tax=Desulfuromonas acetoxidans DSM 684 RepID=Q1JXC5_DESAC  E=1e-34 s/c=0.48 id=23% cov=71%
-----------------------------------------------------------------------FGAIAAANALSDVFAMGGQPITAMNMVGFPNCLPVDVLTEILKGGTAKVHEAGATMVGGH-SVEDEEPKYGLAVT----GTVHPDNLITSQGCKPGDILVLTKPLGTGLLTTALKAEVINEAQITEALqgMARLNRYASEAMRQVGISACTDVTGFGLLGHALEMAEASGIRLLISGSSLPEYPLARDMAE-TGLVPEGSFrnnrhymprvtgaehqaqadidllcdpqTSGGLLMAVHPERLDALCQALKHA--GDHAFVIGEVADGPAGTME---------------------
>UniRef50_Q3ANP7(494-763:768) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Bacteria RepID=PURL_SYNSC  E=1e-13 s/c=0.30 id=15% cov=48%
-----------------------------------------------------------------------------------LSCVGAEPLAVTDNLNFPSPETPKGFWQLAmacRGISDACRTLNTPVTGGNVSLYNETKQDdgtmQPIHPTPVIGMVGGVDDISRVTClawqQPGDAIFLIGvppedgadpSLGLAGSAYQQQTLGSLAGRPPKPDLaieAAVGSLVREAIAQGLLASAHDCSDGGLAVALAESCIASDLGISV--------------------------------------------------------------------------------------------
>UniRef50_C3N8T5(2-296:318) AIR synthase related protein domain protein n=11 Tax=Sulfolobus RepID=C3N8T5_SULIY  E=1e-34 s/c=0.51 id=23% cov=84%
------------------INKFIYNLPTGDCLTC--PSIGEDAAVLETKGEYLIVHSDPITE-----AKSDNGFLSIAVACNDINMKGAQCRWVNSVILLS---DISHLDGIISGISEACNLIGCKVVGGHTEVTSNVKQD--IVITTAMGT--SNKFLNYKSVKEGMKVVLVGSPGIEGTWILAKDYselllEKGVSREVIEKAKGFKMDIivqqRALSILDYVAAMHDATEGGVMQALLEIAKATGYTVLINLDKIGLRYETKIITKALNIDPLKLISSGSFIVI--SNHPEKILERIS------EAYVIGEIKRGDSVLEIKGVGT----------------
>UniRef50_B2V0F0(15-345:345) Selenide, water dikinase n=4 Tax=Clostridium RepID=SELD_CLOBA   E=2e-34 s/c=0.45 id=18% cov=81%
-----------------------LPKFEDENLIVGFDTSDDACVYKINDDTVVIKTVDffpPMVDDPYTF-----GQVAAANALSDVYAMGGNPSIAMNLICFPSCLDISIMREILAGGYDKVKEAGAVIAGGHTIADPT-PKYGLCVS----GFARPEEILSNSNAKIGDVIILTKPLGIGIMNTAAKAEliGENKIKEVTSIMSTLNKYAKECTSGLEIHSCTDVTGFGLIGHGYEMASGSKKTIEIFSEYVPIIDGALDYAKM-GIIPEGMYNnldylkdkfvveanisqelqdvlidpqtSGGLLLSLPEKHAKEFLSRIEK--FTPYAKIIGQVLD----------------------------
>UniRef50_B4WQH5(83-395:813) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Bacteria RepID=B4WQH5_9SYNE  E=3e-34 s/c=0.47 id=21% cov=79%
--------------------------------GPGENAGVIDVG----NGMQVAFKIESHnhpsAIEP--FQGAATG---VGGILRDIFTMGARPIAALNSLrfgSLEDARTRQIFTGVVSGIAHYGNCFGVPTVGGEVAFDRAYSGNPL-VNAMAIGLMETDEIVKSGAVGVGNPVLYvgstTGRDGMGGASFASAELSDESEANRPAvqvgDPFLEKSLVEACLEAfktGGVAAAQDMGAAGITCSTAEMAANGDVGIELDLDLIPEREP-----GMVPYEYLLSESQERMLFVAHAGRELELIDIF--HRWGLQAVVAGSVIEEPIVRI----------------------
>UniRef50_A4GJ93(28-331:339) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=uncultured marine bacterium EB0_49D07 RepID=A4GJ93_9BACT  E=7e-34 s/c=0.48 id=19% cov=35%
------------------IKKSVNATHDKRVLGGIGGFAGLFQLGSKYKNPVLVGCTDGVGTKVALSQAnnktGSIGQDLVAMCVNDMVTCGAEPLFFLDYFAASKLVPKSH-AQIVKSIAKACKLSNCALLGGETAEMP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6UX13(466-716:732) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Methanococcales RepID=PURL_META3  E=8e-23 s/c=0.44 id=18% cov=71%
----------------------------------------------------------------------------VCESVRNLATVGAKPIGMLDNLNFGNPEKPERFYQIkkcIEGLADGAEIIGVPVVGGNVSLYNETVIDGkdypinPTPVISIVGTIENINNIP-KGAKEGDILIITAPTKDEMGGTEYYKQIHNTEEGIVPKAnleveKEIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTNNIGVELDLGDYNTNGLRNDIL-------LFSESSGRIILSVDKNNADKVVKEL-------NGAIIGTV---KGNELKIKLNDNELINLPIEEM-----
>UniRef50_Q05728(83-386:389) Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic n=29 Tax=cellular organisms RepID=PUR5_ARATH  E=9e-34 s/c=0.48 id=22% cov=68%
-------------------------------------------------------------------------------SVNDIITSGAKPLFFLDYFA-TSRLDVDLAEKVIKGIVEGCRQSECALLGGETAEMPDFYAEGEYdLSGFAVGIVKKTSVINGKNIVAGDVLIGLPSSGVHSNGFSLVRRVLArsnlslkdalpggsstLGDALMAPTVIYVKQVLDMIEKGGVKGLAHITGGGFTDNIPRVFPD-GLGAVIHTDAWELPPLFKWIqqtGRIEDSEMRRTFNLGiGMVMVVSPEAASRILEEVKNGDYV--AYRVGEVVNGEGV------------------------
>UniRef50_Q1MRM4(20-347:349) Phosphoribosylformylglycinamidine cyclo-ligase n=51 Tax=Bacteria RepID=PUR5_LAWIP  E=1e-33 s/c=0.45 id=17% cov=66%
--------------------------------------------------------------------------------VNDILVQGARPLFFLDYFA-TSKLDVDKATQVIYGISEGCKQARCALLGGETAELPGMYTEGEYdLAGFCVGIVDQSKIIDGSSIKVGDTIIGLASSGIHSNGYSLVRQiinqcaiepdniipgsRDTFKQVLLKPTFIYSDIICNLIKDISIKGMVHITGGGFYDNIPRVLPQS-VVANIQFSSWDIPPifyWLQEQGSLSWSEMLQVFNCGiGYVLIIPNDSVTRAMNILKSME--VSAWIIGSI------------------------------
>UniRef50_D2RFS1(92-381:761) Phosphoribosylformylglycinamidine synthase II n=4 Tax=Archaea RepID=D2RFS1_ARCPR  E=1e-33 s/c=0.50 id=22% cov=68%
------------------------------------------------------------------------------GILRDVLCMGAQPIALVDPLFfgnldikdLPKGVkhPLYLLFGVVAGIRDYGNRVGIPTVGG-MVFFDESYVTNCLVNVGCVGIVRKDRIVHSRVGNVGDLFVLvggaTGRDGIHGVTFAskelsekseEERGAVQLGNPIMKE--PLIHACLEVVEKGLVTGMKDLGGGGLSCVISEMSYAANCGAEVYLDKVHLKEEGMAPWEI-----YISESQERMMLTVNPKHVDEVLDVFKK--WDVPAVVVGKAIPDKVVRV----------------------
>UniRef50_D2RFS1(455-738:761) Phosphoribosylformylglycinamidine synthase II n=4 Tax=Archaea RepID=D2RFS1_ARCPR  E=3e-14 s/c=0.29 id=28% cov=26%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYACHDLAEGGLAVALAEMCIG-GFGCKVDLS------------ELRGEDYVKLFSESNTRWLVEVDNAEDFVKFMKS--KGLSVYAIG-VVEGDEIVVKN--------------------
>UniRef50_A1VE87(14-344:351) Selenide, water dikinase n=13 Tax=Desulfovibrionales RepID=SELD_DESVV  E=2e-33 s/c=0.44 id=23% cov=72%
--------------------------------------------VRVPGGKAIVQTLDFFT--PIVDDPYLFGQIAAANALSDVYAMGGEPWCALNIVCFPvKELPEEILADILRGGADKVREAGAVLVGGH-SIEDESIKYGLSVT----GIIDPDCYATNTGLRPGDVLLLTKPLGSGVLATAVKAGWDGFEAheqELGRWGAMLNRAGGRVIRELGLAAATDVTGFGLGGHLLEMANASNMSVHVDVSTLPlmpavldlvatgllpagshanrhfcsgnvsVHPEVDSLLVDIVFDAQTS---GGLILAVPPHLVDDACSILRAE------------------------------------------
>UniRef50_A8HRC1(77-408:415) Selenide water dikinase n=1 Tax=Azorhizobium caulinodans ORS 571 RepID=A8HRC1_AZOC5  E=2e-33 s/c=0.44 id=20% cov=87%
----SLAHGGgcGCKLAPSVLQELLAGAPAAqpyaqllVGMETGDDAAVWDL----DGETCIVATTDFFM--PVVDDPDHFGRIAATNAISDVYAMGGTPIMALAILGMPlGKVDTGIVRKILEGGSAACAAAGIPVAGGHSI-----DSVEPIYGLAVIGTVRKALVRRNADARPGDALILTKAVGVGVYSAAFKKEALSSDAydEMIASTTLLNKVGSALAKDSAVHAMTDVTGFGVIGHALEVARGSKLAVTIEADRVPlmahaealvrqgfvtgasirnwasygaearLPADFPEWRRHLLTDPQTS---GGLLVSCAPEEADRLVEEIQAAGY-PNARRIGAVTEG---------------------------
>UniRef50_C0B9V8(13-329:337) Putative uncharacterized protein n=1 Tax=Coprococcus comes ATCC 27758 RepID=C0B9V8_9FIRM  E=2e-33 s/c=0.46 id=19% cov=75%
----------------------------------------------------------------------DLGVFAIAQAVDQLASRGARAYGISVRIMLPTFAYESRLKAMMVEISEICKEKGLRVFFADAQSVNGIQTS--IVHVTAHGEAKKEQLLASRSAKAGEEIVLVKWIGMEGTlriireegAALAERFAPGFLNKLEDMRDEIfSDRAMEIAGRNGVSAMHPIGEGGILAALWDMAEGAGIGLSVEMKKMTVRQETIEVCEVFHLNPYQLTSTGAVLMVTPKG--EELKERLKRE--GIPAEIIGHTTEGNERIIWG--GGEKKISRQTG-------
>UniRef50_C4XQL6(12-317:320) Thiamine-monophosphate kinase n=2 Tax=Desulfovibrio RepID=C4XQL6_DESMR  E=2e-33 s/c=0.47 id=25% cov=45%
----------------SLMDAHFPRQAAGVELPRGDDAAVVAVPA------RLCVTSDLFVEDVHFrrsyFTPAEVGAKSLAVNLSDVAAMGGTPTGFVLGIVCPDDADRDYWDAFLAGMAALAASHDVPLVGGDLSR-----GDKIAVSVTVWGApGPSGRFLTRGAGHPGDILVAVGDLG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A0LA23(25-351:353) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=cellular organisms RepID=PUR5_MAGSM  E=3e-33 s/c=0.44 id=23% cov=68%
----------------------------------------------------------------------------VAMSVNDLVVQGAEPLFFLDYFAC-GKLSPETAATVVEGIATGCRAAGCALIGGETAEMPGFYTEGEYdLAGFAVGAVDKHKIIDGRHISPGDAIIGLASSGPHSNGYSLIRKlvlgqsGPGLEADfngkplgevlLTPTHIYVLPLLE-LAKTHAIHGLVHITGGGFWENIPRILPDA-TGALLKRSCWQQPEvfnLLQKLGNIAEDEMLRTFNCGlGMLVIVPATQADSALAQLRAA--GEQAELVGEIT-----------------------------
>UniRef50_Q1GRI7(12-314:317) Thiamine-monophosphate kinase n=2 Tax=Sphingomonadales RepID=Q1GRI7_SPHAL  E=3e-33 s/c=0.48 id=21% cov=68%
--------------------------------------------------------------------------------LSDLAAKGAAPVGVLVGYSLG---DAAWDAGFVEGLDGALRRFGVALLGGDTVRAPTGTPR--SFGLTAIGRAPEGGAPTRGGARPGDQIWVTGTIGNAGLGLAMRLGQVEPNETCLAAYCRPQPQLTFGQAVAPHVHAMMDLSDGLLIDAQRMAAASGCELGIMMDAIPLSAALLAVRPdvlDTRLAAATAGDDYQLLFAAVPAAADAIREI--AAGLNVAVTAIGHAGVGEGIVL----------------------
>UniRef50_Q6AFK0(17-317:331) Thiamine-monophosphate kinase n=1 Tax=Leifsonia xyli subsp. xyli RepID=Q6AFK0_LEIXX  E=4e-33 s/c=0.48 id=24% cov=80%
-----------------------------PRSAAALVGPGDDAAVLVAPDGRYVVTTDLMVHGPDFRlawsSPADLGWKAAATNLSDVAAMGAVPTALVVAIAAPPALPVVALEEIAEGLRAACEalALGCGVVGGDLSASET-----LTLAVTAFGDLRGRSPVLRSGARPGDILAVSGRLGAAAAGLRLLfrhavdaagapdraafeRVAADHPDLVAAQLRPAPPIADGPLAAEAGATAMLDLSDGLTIDARRVGEASGVAIDLDPDALGPDPRL----------ALTGGEDHSLLASFPPDAA-----------LPGGFRRVGAVLEGEGLFVGGRPFGER--------------
>UniRef50_D1U8X7(28-342:353) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Desulfovibrio aespoeensis Aspo-2 RepID=D1U8X7_9DELT  E=4e-33 s/c=0.46 id=22% cov=69%
----------------------------------------------------------------------------VAMSVNDVLVQGAAPLFFLDYFA-TGKLESGVAEQVVAGVCEGCRRSDCALLGGETAEMPGFYPDGEYdLSGFAVGMVDTPRLVTGTSVTPGDVLIGLGSSGAHSNGYSLIRKLFDQSGLRPDQPFPGSDRtvaevlieptkiyvraVLALLQTIGIKGMVHVTGGGFYDNVPRVLPET-TTARIEFGSWPILPvfdWLKTEGRLSWPEMLQIFNCGiGYILICSPENAEKAMELLDARD-DVDAYRIGEITPRE--------------------------
>UniRef50_B9KZE5(23-353:359) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9KZE5_THERP  E=5e-33 s/c=0.44 id=24% cov=74%
----------------------------------------------------------------------GIGIDLVHHSANDLLACGAEPLFFLDYFA-TAELEETVLEALVRGMTRACGALGCALIGGETAQLPGVYTPGAYdLAGCMVGVVPVEGIIDGRRIEPGDLVLGLPSDGLHTNGYSLVRAVLGLTGNPQHDrpllaevppwsdrslgdlllqpHRCYVPLLRTWLRDSRLHGLAHITGGGLTGNLSRIVPD-GCRIEIDASSWPVPPlfeEIRQRGSISPTEMFRVFNMGIGFAVI---GTPSFIHALQQALG--EGWIVGHVVraERPRVIVRGGMLGMQIL------------
>UniRef50_B7H4T6(428-716:739) Phosphoribosylformylglycinamidine synthase 2 n=87 Tax=Bacteria RepID=PURL_BACC4  E=4e-25 s/c=0.41 id=20% cov=73%
----------------------------------------------------LAMTTDCNSRYIYLDPEMG-GKIAVAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIeksVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTvgMVGLVHDLKHVTTQEFKqAGDLVYVIGETKAEFGGselqkmIHGKIFGQSPSIDLDVELKRQKQVLEAI-QAGLVQSAHDVAEGGLAVAISESAiGAKGLGATVKLD-------------GEATAALFAESQSRFVITVKRENKEAFEKA-------VEAIQVGEVTSTNEVTIHNE-------------------
>UniRef50_B8J5H7(16-355:355) Selenide, water dikinase n=3 Tax=Anaeromyxobacter RepID=B8J5H7_ANAD2  E=2e-32 s/c=0.42 id=28% cov=90%
----SLSHGAGuaCKIRPADLAQVLrrLPAVDDPRVLVGH-STRDDAAVYALDAERAVVeTVDFFtpvVDDPYWF-----GRIGAANAFSDIWAMGARPLFALNLVAWPvKTLPMEMLGEVLRGGAETARLAGAPVVGGHSIDDPEPKY-----GMAVTGLVHPDRVLRNVGARPGDRLLLTKPLGSGIITTAIKRGiapAPMIDAAVEVMSALNRAAGEVLAESGAVRALTDVTGFGLLGHAWEMAEGSGVALRLHAGAVPVLPGVLDLaakdvlpggskANLAWVEPaLRVApgvaealpavladaqTNGGLLAAVDAARAGAVLEALRAA--GVAAVEVGEVLPG---------------DPPRIELVP---
>UniRef50_C7HVN7(1-331:339) Selenide, water dikinase n=1 Tax=Anaerococcus vaginalis ATCC 51170 RepID=C7HVN7_9FIRM  E=3e-32 s/c=0.43 id=19% cov=76%
-----------------------------------------DCALVRVDKNNGIVSTlDffpPMVSDPYIF-----GQIAAANALSDIYAMGAEPICGLNIVLFPEDENINILKKILQGGASKVIEAGASLVGGHSIHDPK-----IKYGLSVTGKVDIDKVWKNNTPNEKDILILTKPLGVTLVTNAygiNILGQKEMDKAISSMIF-LNKYAKEILEKYRISSATDVTGFSFMGHLSEMLGD-KYSAIIDSKNIPILDGAKKAASEFVFtkggqrNRMHMENMveflvddfaleevlydpqtsGGLLVSIHKDDAKDALEELRKN--NINAKIVGQISKK---------------------------
>UniRef50_Q21Y09(426-751:765) Selenophosphate synthase n=5 Tax=cellular organisms RepID=Q21Y09_RHOFD  E=3e-32 s/c=0.43 id=27% cov=78%
------------------------------GLSDPDDAAV----VRVPAGKAMVHSVDffrSFIDDPYLF-----GKVAANHALGDIWAMGAQAQSATAIATVPSGLEskvEDVLFQMMTGALEVLNEANCALVGGHT-----GEGKELALGFAINGLIDDDpaQILRKNGMCPGDVLILTKPIGTGTLFAAHARlsaKGRWIDAALQSMVVSNQKGAQCLREF-GATACTDLTGFGLLGHLVEMTRPSGVDAELDLGALPLLDGAQECVAAGIVSSLQSANvrlrralrnqeamvnhpryplifdpqtAGGLLASVPADKAQACIAALRELGYSHTVA-IGRV------------------------------
>UniRef50_Q0F396(5-287:305) Thiamine monophosphate kinase n=1 Tax=Mariprofundus ferrooxydans PV-1 RepID=Q0F396_9PROT  E=3e-32 s/c=0.50 id=22% cov=66%
----------------DLIDRCFAGRGGQPrtftRLGIGDDASVHQPAA----GMELVVSTDTSLAGVHWptdLPLAVAADRAVCAALSDLAAMGAEALCCWLNVMAE---DAGAVAQMGDGATAALARFDVELVGGDTTRSSCNA-----LAVTVAGQLPAGSAMRRSGAQAGDNIWLCGCVGFHASGLKQWINDCK-DGSFVEYFTGVVPMLKQGVRLReqGVQCCMDISD-GLLQDATHLACASDVGMEIELSLLP--------------------------------------------------------------------------------------
>UniRef50_B3T9Z5(17-315:323) Putative AIR synthase related protein, C-terminal domain protein n=1 Tax=uncultured marine microorganism HF4000_APKG7N23 RepID=B3T9Z5_9ZZZZ  E=4e-32 s/c=0.47 id=20% cov=87%
------------KATEALIAQI--KSVGRKGDGEAIKLENGFAGLVKLGDGALAICTDGVGSKLLLAGELDsihtVGIDCVAMNVNDLICVGAEPLSFVDYVAL-DKPDEDLMGKIGMGLAEGCRRANCTLSGGETAILPEL-VHGFDIAGTSVGYVKQEDIIDGTKISEGDVLIGLKSSGPHSNGYTLIRKLFDGDKEigkqLVEPTRIYVKEIMDLIKQVDVHGIAHITGGGL-DNIGRINDNFQYVIDNPLPVPSVFDWLQEKGEVEDSEMYRTFNMGmGMIVIVGEKNAEEAASIL-----GSDAQIIGSVRNGQGV------------------------
>UniRef50_B9KZ38(45-358:733) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Bacteria RepID=PURL_THERP  E=5e-32 s/c=0.45 id=24% cov=73%
------------------------------------------------------------------FQGAATG---VGGIVRDIFAMGARPIALADSLRfgpLEEPRQQYLFHGVVGGIGWYGNCLGIPTVAGDVFFAPEYRQNPL-VNAMCVGIAERSALIRARATGPGNLVVLvgadTGRDGIHGATFASVE---DPERSHRGVVQVGNPFLEKLlleaclevLETGAVVAMQDLGAAGLTSASAEIAARGGTGIELDVALVPRRE-----TGMTPYEVMLSESQERMLLVVDPEGIDRVLAIFRRWELH--AVVIGRVTDDG--LLRVLEDGQVVAELP---------
>UniRef50_B9KZ38(437-722:733) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Bacteria RepID=PURL_THERP  E=8e-13 s/c=0.27 id=17% cov=64%
-----------------------------------------------------------------------------------VSCVGAEPLAITDCLNFgnPERPEIyYQLVQAIEGMAEACTVLGIPVVSGNVSLYNETEGRSIPPTpvVGIVGRLADVRRCVGMGFRGEGKVFLLGSelATLGGSEFLAQRHGLVAGAPPPLDLeleRRVQACVREGIARGIVLAAHDCSEGGLLIALAESCMVGRIGGRFTTES------LIAANGRLDR-ALFGESASRVIVQVAEGAEGALLGLARAH--GVPVQELGR-------------------------------
>UniRef50_A3EVN2(52-361:737) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Leptospirillum sp. Group II RepID=A3EVN2_9BACT  E=6e-32 s/c=0.45 id=21% cov=69%
----------------------------------------------------------------------------VGGILRDVIAMGARPVALANSLVfgsLRHPKHRTLFQRVVEGIAGYGNPAGIPTVGGEIWFDDRYQHN-ILVNVMAVGIVNNNEIMSAKASQKGLLAIYignrTGRDGVSGAAMASRgfsKDGADLRPQVQiADPYAGKNLMEATLEIARKKladSIQDMGAAGLTSSSTEMAGRAGLGMELDVSCVPLRDKTMEPWEI-----LLSESQERMLVLSCPENAEKILDIARA--WHLSAAIVGRTIQEPNFVV----------------------
>UniRef50_Q9HJA4(65-384:759) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Euryarchaeota RepID=PURL_THEAC  E=6e-32 s/c=0.44 id=22% cov=71%
------------------------------------------------------------------------------GIVRDVLCMGAQPVALIDSLFLGdvssdryEGLlsPRYIFGGVVGGIRDYGNRIGIPNVAGSLYF-DKLYNSNPLVNAGCVGIVRRDRIVRSKSYKPGDVLVLmggkTGRDGIHGVNFAsttlgkvtkSSRLAIQLGNPIVE--QPMIKAVLEANDAGLIRAMKDLGGGGLSSAATEMVYAGGFGAEITLDDIKLKES-----NMSGWEIWISESQERMLMECYPEDVEKIRQI--AEKWNLDFSVIGQVTADRRIRV--YYKKRKIIDM----------
>UniRef50_B0XEZ0(14-324:336) Selenide n=4 Tax=Culicidae RepID=B0XEZ0_CULQU   E=6e-32 s/c=0.45 id=18% cov=85%
------------------IDKEGKSSTDNEGVGIGLDSSVIPL----KNDLQLVQTVDFFY--PLIDDPHMLGRIALANVVSDVYAVGALAIdEIKLVCSAPTEFSEAErdivVPMIIRGFQEAAAEAKCPAKIGSIALNP-----WCIIGGIATAVCHKSELIMPYNAQPGDALVLTKPLGtqLATNAFIWMTEEAENWTKLAAHLTPaeversyaiavesmsrLNRSGAELMHKFGAHAATDVTGFGLFGHAENLLKFQKADVDFELDTLPIIRNVVKIAEILGRTPKLMAGkavetSGGLLLSLPAENAEKFCAEYRTVSEH-DAWIIGKVVPGSRVL-----------------------
>UniRef50_C7BHY4(46-294:351) Putative uncharacterized protein n=1 Tax=Photorhabdus asymbiotica subsp. asymbiotica ATCC 43949 RepID=C7BHY4_PHOAA  E=7e-32 s/c=0.56 id=23% cov=54%
----------------------------------------------------------SFVANHPYFA----GWSAVMANISDIAAMGGRALSVVNSFW---HTSSEHAQLLMQGMQDACRAYGVPLVGGHTNL---GVVYQPTLSVAIQGIARK--LLSVLHVKPQQKILIALNLqgKFHSNTTYWKCFERVSDHILQSQIALLP----QLAEANLVHAARDISNAGILGSLLMLLEATASGAHINLDAIPKPDDV---------------------------------------------------------------------------------
>UniRef50_B8D417(41-359:731) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D417_DESK1  E=8e-32 s/c=0.44 id=19% cov=85%
---------------------------NHVVLGPGRDA----PAVEVFPGILAVFKIESHnhpsAVDPYNGAATGIG-----GIIRDILTLGAKPIALLDLLYMGNPFNPHakwLIRNIVKGISDYGNRVGVPVVAGDTWFDESFNK-QPLVNVACLGIVEKNKAVL-SKPRPGDLVVIignsTGRDGLLGSSFASAPLKDNMVEDIGAvqigdalMEKMLIDVVNEVVEKKLVDYIKDLGGGGLTTAISEAAGDYDLGVEIYLDRLHLR------MDLEPYEILASESQERMLLAVPRENFNELIGILEKYE--VPYSVIGIFNDSG--FIRVYYKGRIIAEVPSKAMArPR--
>UniRef50_Q8TW12(23-337:345) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Methanopyrus kandleri RepID=PUR5_METKA  E=9e-32 s/c=0.44 id=19% cov=87%
------------------IRDVLEKYKVEPEGCREVEGIGHYAAVLEVHGELLTLNVDGVGSKVLVAqlvgRYDTVGIDAIAMNANDAVCLGARPLAFLDYLAMEDP-DPDVCAEIAEGLGKGAREAGAPIVGGELATLPevirgKEEGRGFDLVVACLGRVEGD-PITGEDVEPGDAIVGLRSSGIHSNGLTLARKVLLSEYDVHDELPHGRTVAEELLEptriyvrpvmevlrDYEVRGIAHITGGGV-ENLKRLRDDVRYVLDDPFEPHPVFEIIRELGNVPVEEMYRTFNMGmGMALIVPEEEAEDVVDTVSKH---VEAKIVGHVEEGRGVVV----------------------
>UniRef50_C1F5Y2(505-756:785) Phosphoribosylformylglycinamidine synthase II n=3 Tax=Bacteria RepID=C1F5Y2_ACIC5  E=5e-20 s/c=0.40 id=21% cov=58%
----------------------------------------------------------------------------------------------------------------IDGMAEACTALGTPITGGNVSLYNETRGEGIYPTPVIgvVGILDDvTKSVPAHFQRAGDLVYLvggksiAGAIGNAlhtfGATEYARQRFAHLWGDVPAlhldDEAALHRALAELAQASAVQSVNDVSDGGLAVALAKNCFPRQIGVRVEvSDPTGTPPEMMLFHEDASL----------VVASVAPEKKDDFLRIIAAHAQ-LFAVQLGETVKQRFTILRN--------------------
>UniRef50_Q8REV3(49-332:339) Phosphoribosylformylglycinamidine cyclo-ligase n=10 Tax=Fusobacterium RepID=PUR5_FUSNN  E=1e-31 s/c=0.49 id=18% cov=66%
--------------------------------------------------------------------------------VNDVLCHGAKPLFFLDYLAC-GKLDAEVAAQLVSGVTEGCLQSYAALVGGETAEMPGFYKEGDYdIAGFCVGIVEKEDLIDGSKVKEGNKIIAVASSGFHSNGYSLVRkvftdynekiflkeygENVTMGDVLLTPTKIYVKPILKVLEKFNVNGMAHITGGGLFENLPR-CMGKNLSPVVFKDKVRVPEIFKLIAERSKIkeeELFGTFNMGvGFTLVVEEKDVETIIELLTS--LGETAYEIGHI------------------------------
>UniRef50_B3DVC1(21-333:336) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3DVC1_METI4  E=2e-31 s/c=0.44 id=21% cov=28%
----------------------------------------------------------------------------VNHCVNDIASLGADPLFFLDYIGC-GKLDSSIFLKILQGMVRACKNAGCALLGGETAQMPGIYKEKDFdLVGAIVGVVDKENIIDGKTICPGDLIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8F8I3(44-360:724) Phosphoribosylformylglycinamidine synthase 2 n=1 Tax=Thermotoga lettingae TMO RepID=PURL_THELT  E=2e-31 s/c=0.44 id=20% cov=79%
--------------------------------GPGENAGVVDIG----DNLVIVFKMESHnhpsAIEPFQGAATGIG-----GIVRDIFAMGARPIALLDSLRFGDLKSAKVkylFSGVVSGIAHYGNCIGVPTVAGEIYFDD-CYTDNPIVNVMCVGIAKKDEIKFARAQFSGASVMLvgamTGRDGIHGASFasenLSEKSQEKRPSVQVGDPFMEKLLIEACLEAikiEGVLAVQDLGAAGLTSACSEIASRGNKGIEIDLAFVPQREKGMTPYEIV-----LSESQERMLLVVKPEYEDEVKQIFQRWDL--YSQKIGVITDDGLFTVK---------------------
>UniRef50_A8F8I3(409-710:724) Phosphoribosylformylglycinamidine synthase 2 n=1 Tax=Thermotoga lettingae TMO RepID=PURL_THELT  E=1e-21 s/c=0.35 id=18% cov=84%
----------------------------NTVVLPGSDAAVLR---IKGSSKAIAVTTDcnGFYC---FLDPYEGAKIAVAEAARNLVATGAMPVGITDCLNFASPDDPKVayqLKRAVEGMAEAARFLRIPIVSGNVSLYNESKKRKIYPTPVigMVGLIEDISYICDAAFKnEGDLVVLIGENFSESACEYTKVIWGIDYGKVPSIDLEVEKRVQQvclkAIREKIVSSAHDLSEGGLAVSLAESSILGNIGVICDLRANIRRDFV-----------LFGEQQSRMIVTIKKENLPLLKKI--AEDNNISICVIGRV-AGKKFII--SVNGEKVIDLNIDEI-----
>UniRef50_C3N674(391-675:709) Phosphoribosylformylglycinamidine synthase 2 n=12 Tax=Sulfolobaceae RepID=PURL_SULIA  E=4e-08 s/c=0.22 id=20% cov=54%
----------------------------------------------------------------------------------------------------------------IRGIGEATRFFNIPIVGGKVSFYNENSQGKPIKPTPLIvmaGLVQGKLLKNR--VEDSSYVVLLGytrkELGGSLLSKIFKVPSQAPKVRLQEDLLSSEVVIDAINE-EKITFAKDISRGGLAASLFNIIVH-GYGVEI--STKSILSDTDNVVEN-----LFSESSGRFVILTNE--PEWIVE--KSRSKGIVASIIGKV------------------------------
>UniRef50_C4ZDB0(10-339:342) Selenide, water dikinase n=22 Tax=Bacteria RepID=SELD_EUBR3   E=3e-31 s/c=0.42 id=21% cov=71%
------------------------------------------------------------VDDPYTF-----GQIAAANALSDIYAMGGTVKTALNIVCFPEKMDLNILGKIMQGGADKVIEAGGTLAGGH-SIADSDVKYGLSV----MGTVHPEHIYSNNTGQPSDVLILTKKLGVGLVCNANRVGEapLGAIEDAVSSMTTLNKAASEISHAFDIHACTDVTGFSFLGHLSEMLND-DITALIDSISIPVITGALRCADEFFLTaaaqrnrnhvgdkvcfakniPFSMEEvlfdpqtSGGLLFAVKASEADAFLHELKAA--GLPAAKVGRFVKRRDV------------------------
>UniRef50_Q03E81(16-347:349) Phosphoribosylformylglycinamidine cyclo-ligase n=6 Tax=Lactobacillales RepID=Q03E81_PEDPA  E=4e-31 s/c=0.41 id=21% cov=65%
-----------------------------------------------------------------------IGQDLVAMCVNDLLAQGALPLFFLDYLALS-HLEKNQVQKILNGILKACQAQSITLLGGETAEMPGiYQKHHFDLAGFAVGLTAKRNLLQAKNVHNGDYLIGLPSSGLHSNGYSLVRKILfedhdfqfddqlaglngSLIEELMQPTRLYVNVIRPLLKQKLVNGIAHITGGGLLDNVPRMLQDQQ-QAEFKLDSWEKPTIFKILAELGKLsqtDCYETFNMGiGMVLAVSPDNYARVVAEL---------------------------------------------
>UniRef50_A0B908(89-396:456) AIR synthase related protein n=26 Tax=Archaea RepID=A0B908_METTP   E=4e-31 s/c=0.44 id=22% cov=90%
------SRGLGDFYMHTKIAEVIGRTGAVVDSSQLDDSGVVKAG-----DKYLIVTVDGMhsrLSDYPFLAGFHVTRAA----LRDILVMGARPVALFSDIHLADDGDVAKVLDHIAGIATVGELVNVPLITGSTLRIGGDMVIGDRLTG-CVGAVgIAERITPRKDAAPGDVIIMT--EGAGGGTICAAALYYGMHDVVEETLniKFLEAAGALIDEGPEIHAMTDVTNGGIRGDAKEISHTAGVKMVFFEERMRslVNHRVLEMLERLEIDYLGVSID-ALLIIAPEREADVILGVIEKA--GVAADIIGRVERGSGVELHTKEGIK---------------
>UniRef50_B1XMJ9(395-723:730) AIR synthase related protein n=2 Tax=Chroococcales RepID=B1XMJ9_SYNP2  E=5e-31 s/c=0.42 id=20% cov=77%
-----------------------------VGLEQPDDAAIIQ----IPRDQLLVQTIDYFpsLLNDPFL----LGKIVTHHCLSDLYGMGAKPHSVLVLATLPHGpatVQQGMLQQLLAGVVEILNLDDIALIGGHT-----NEADQLGLGLTCNGLLQKDAIWRKTELARDQLLILTKPLG-TGTLFAAEMQGKtkghWIDGAIATMVQS-NKTAAEILRSHGATACTDVTGFGLAGHLLEMLQPKGFSAALHLDQLPILEGAIETLQrgltsslapqnhtaeqfiqvtmaqrerpeyELIFDPQTS---GGLLGAIAPEKAQACLQALRAEGY-PHSVVIGHI------------------------------
>UniRef50_C1SM36(24-343:345) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SM36_9BACT  E=6e-31 s/c=0.43 id=23% cov=68%
--------------------------------------------------------------------------------VNDIIVTGAKPLFFLD-YMATGKLSSEKMAQVVEGIAEGCRQAGSPLVGGETAEMPGmYSGEDFDLAGFAVGILDKPKAVTGERISKGDVLVGLPSSGLHSNGYSLARKlffeklSMKPDDILYDDVMLKHALLEPtriyvqqvlsvIEKGIDVKGMVHITGGGFYDNIPRILPE-GAGVKINPDAFPTPGIYKFILEKSGIEEkelYRVFNMGiGYIMVLEHSEAEKCMSLID------DACVIGNVTDTGIVEIEG--------------------
>UniRef50_B7A847(29-306:313) Thiamine-phosphate kinase n=1 Tax=Thermus aquaticus Y51MC23 RepID=B7A847_THEAQ  E=8e-31 s/c=0.49 id=26% cov=69%
----------------------------------------------------------------------------VAATASDLLVKMGRPLGFTLGLFLPPELEEAFALGLVQGAAEAAGRLGAPLLGGDT-----NAGEEVALTVSGFALSHAPLPRR---ARPGDLLFLAGDrWGRVGAAILAHYRGRSLEGfpEIRQAAFYPLPRLELLALSGLLRGGLD-SSDGLAETLWQL---SELGVRVDLEALPLYPDVLAFAggEDEALElVLYGGEEFEAVLVVPPEAEGAVLA--RAEAVGLPLFRAGRVGEGEGVYLRGRPVLRR--------------
>UniRef50_C4LH52(485-839:862) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Corynebacterium RepID=C4LH52_CORK4  E=2e-15 s/c=0.24 id=21% cov=84%
--------------SRAFITEQYDRYVMGNTVEAQNADAGV-LRIDESTGRGVAVSADA--SGRYTKLDPNMGaRLALAEAYRNVVVTGARPVAVTNCLNFgsPEDPAVMWqFREAVHGLADGARELGIPVSGGNVSFYNQTGSEAIlptpLVGVAGVvtsvdhhinhllgGLTTERSAFPESESDAGDDssastsgsandqfeeLYLLGETHDELGGSIWQQVKHNALSGLPPqvDLAATSALADFFCDQADpdtprvVTAAHDLSEGGLAQALAELAMISGVGMDVDVSKVHADPCV----------ALFSESANRVVVACAHGDGDKLVSLAKR--CGIPVLRLGSVTSR---------------------------
>UniRef50_Q5ZUW5(45-357:358) Phosphoribosylformylglycinamidine cyclo-ligase n=24 Tax=Gammaproteobacteria RepID=Q5ZUW5_LEGPH  E=1e-30 s/c=0.43 id=22% cov=85%
--QVLTGIGSFG-AMYDL--KPFMEKFKHPVMVQSIDGVGTKTIVARMMQKF-----------------DTIGIDLVSATTNDIIVLGARPLTLLDYIA-TDRLKPEYIEEIIIGMTQACLENNISLVGGETAEMPDTYLKGEhDLVGIITGVVEKDEAILGKDITPGDSVLAFPSSGLHTNGYSLARKLLfelggytvesqldELDATVGEALLVPhinytNPVLHLLNNKIPIKGMAHITGGGVLENIPRVLPN-HCSVEINKNSCPVLPIfnvLKALGKLDDQEMYRTFNMGiGLVMIASPGVVSEIYTALKEFP-NFPVYEVGKVVSG---------------------------
>UniRef50_C7MMK4(39-375:411) Phosphoribosylformylglycinamidine cyclo-ligase n=7 Tax=Coriobacteriaceae RepID=C7MMK4_CRYCD  E=2e-30 s/c=0.40 id=24% cov=68%
--------------------------------------------------------------------------------VNDILATGAEPLFFLDYIAV-GKLKSEAVAEIVGGIAEGCRQAGCALIGGEMAEHPGvMDPEEYDLSGFSVGVVDRARMLDPENVTEGDVLLGLASSGLHSNGYSLARK-VCLEGRTHYEVRLPQSLLggesvqDALLEptriyvksvhtaltnhPHAVHALAHITGGGITENLNR-ALPSHLDAQVDIGSWtmkPIIPFVCRAAKLSESEALKTFNMGlGLVLIVDAAAVDSVEHTLQ--EAGEEVFRVGHVVAGSGAV-----------------------
>UniRef50_Q18CW2(14-357:358) Phosphoribosylformylglycinamidine cyclo-ligase n=8 Tax=Clostridiales RepID=Q18CW2_CLOD6  E=3e-30 s/c=0.39 id=18% cov=49%
----------------DLIKGKIKGTYDGNVVGDLGNFSGLYSLKDFVGMKEpvLLASTDGVGTKLKIAQMMDkhdtVGIDLVAMCVNDLICQGAKPLFFLDYIALGKLVP-EHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGeDDYDLAGFSVGIADKEKIVSGNNVKSGDVLVGISSSGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A7I780(45-319:338) AIR synthase related protein n=6 Tax=Methanomicrobia RepID=A7I780_METB6  E=3e-30 s/c=0.49 id=16% cov=66%
----------------------------------------------------------------------------------DIAAMGGRPIAMVDVFSMPKNTHIH--EQVVKGMHDASAQFGVPIVGGHLHPDAPYS----VIDVSILGSARLDSIIYSNTAQEGDHILAAIDLsGRVHPSCALNWDSVTMKTA--AYVRAQIALLEEIGKDHLVTAGKDISNPGLIGTLGMLLEVSGRGAEIDLGKVPKPDL---AANAMTFEQWVKMYPGmGFILTARKQNVDELVRRFAA--VGMTAHDIGTVDATRRLRIR---------------------
>UniRef50_D1Z279(31-331:334) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Methanocella paludicola SANAE RepID=D1Z279_METPS  E=5e-30 s/c=0.45 id=23% cov=66%
--------------------------------------------------------------------------------VNDLYVMGVEPLAFVDYVSIEKP-DDELIRQVMVGLDEGARQANISIVGGETAALP-DIIKGFDLAGTAVGYVGKDKVVTGEGIAPGDVVIGLPSSGIHSNGYSLVRKvveksglkytdplPYDKKKTIGAELLTPTRIYAEVVPIFRkypVKGMAHITGGGLMN----LRRITGYGFEFN-DPLPVPPVFTWLQKLGGIDdeeMYKTFNMGmGYVIITDKESAGAIVKM-------TDGKIVGRIVKE-GCTVRGT-------------------
>UniRef50_A8RRZ1(6-271:282) Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC BAA-613 RepID=A8RRZ1_9CLOT  E=5e-30 s/c=0.50 id=24% cov=67%
------------------------------------------------------------------------GQIAAANSLSDVWAMGGEARLCMNILMFPEHLPFETVQAILRGGYDKVAEAEAIVVGGHT-IKDDIPKYGLCVS----GVVHPDRILRNNSIQKGDVLILTKPLG-TGVLTNADRGGLLSDSEHKAMvdcMAALNKyAADAVRNLDGVHACTDVTGFSLLGHSYEMCGESGLTVIIDSSRVPLLPGADSYASMglvpavayqnmnhlkdkvalpkdlpshvhdLLFDPQTS---GGLLYSVASQEAGRIMEALQKACQ--SPAVIGHV------------------------------
>UniRef50_A9NA98(23-350:352) Phosphoribosylformylglycinamidine cyclo-ligase n=162 Tax=Bacteria RepID=PUR5_COXBR  E=6e-30 s/c=0.41 id=17% cov=46%
---------------ADLVEAIkpIAKRTRRPGVLSGIGGFGGLFELPRGYKQPVLVSgTDGVGTKlklaVELNRHDTIGIDLVAMCVNDVITTGAEPLFFLDYYA-TGHLNNEQAKQILTGIGAGCELAEVALIGGETAEMPGLYRQKDYdLAGFCVGVVEKEKIIDGSRVRVGDALI---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4YCP4(9-299:313) AIR synthase related protein domain protein n=1 Tax=Metallosphaera sedula DSM 5348 RepID=A4YCP4_METS5  E=6e-30 s/c=0.46 id=19% cov=81%
---------------HSFIETVISKYVNS------------DVNLDVYRQGNVVLKIDGFPIKytMPFMDFYDLGWKAVVAAMSDLVSYGATPLVVLSSFGLSPEIESKNAEMMIMGISDASKYYGATYGGGDTNSSEDSG----WIDIAIFG---NPVCNTRPKAEPGDLVYVTGELGRTTGAFLWYSSGGKFPLPLDSVIKLRHPVInrailRAHRELCSVVALGTDVSDGILVSLNKIAHYIGHGIDI--ANIPLVEYIQELVDKnivsLNEILKSGGEEYETIFVVKKETSSIFLDAMKR--YGVIVKEIGRVID----------------------------
>UniRef50_Q3ARU4(67-361:761) Phosphoribosylformylglycinamidine synthase 2 n=18 Tax=Bacteria RepID=PURL_CHLCH  E=9e-30 s/c=0.45 id=21% cov=55%
---------------------------------------------------------------------------------------------------------------------------GVPTVAGDIYF-EEGYTGNPLVNAMSVGIVEHHKTVSATAYGTGNPVLIvgssTGRDGIHGATFASEDLSEASEEKRPSvqvgDPFAEKLLLEatlEAIETGYVVGLQDMGAAGITSSTSEMSargiEKYGVgGIEIDLDLVPIREAGMSAYEI-----MLSESQERMLIVAAKGFEDKIIEVYQK--WDVQAVVIGEVTDDNHVRVK---------------------
>UniRef50_Q0AFI6(4-338:349) Selenide, water dikinase n=3 Tax=Proteobacteria RepID=SELD_NITEC   E=1e-29 s/c=0.40 id=21% cov=82%
---------------HRILQQVRFPAAHSALMVDGryfDDAAIYKIN----EQTALVQTLDFFT--PIVDTPRLFGEIAAANAISDVYAMGGRPVTAMGILAFPlATLSEHIIVDVLQGASDKIAEAGANFVGGHSIDD-----DTLKFGLSVTGLVNPQQVWTNANAQSGDHLVLTKALGTGTLTAGIKRQQLQEKDimDALESMAAINNVIDYLSPdlLAAIHAATDITGFGFSGHAMQLANASNVTLSIATGNLPRFDkafyclknsfltkahrtnaeyttphiddaKLDALYKLLIHDPQTS---GGLLLSVVPEASQLVLQALRTYFK--PAAIVGTV------------------------------
>UniRef50_A6QAK6(449-716:740) Phosphoribosylformylglycinamidine synthase 2 n=33 Tax=Epsilonproteobacteria RepID=PURL_SULNB  E=3e-18 s/c=0.35 id=19% cov=62%
-----------------------------------------------------------------------------------VAMSGARPLSITDCLNYGNPENPEVMWQFAqgcEGIKEACLELNTPVVSGNVSLYNETNGVSVFPTpaIAMVGLNDDQNKVLPSVFQhEGNNIVLIGETkGEFGGSLYIKELFGETVGTLPSfDYKTelkLWELVIEANKIGLLESAKDVNVGGIAIALSKMAAVSSKGITVKASVSNSRDIFDE-------------SQSRALLEVADADLEELLDM--AAGLGLKAEVIGKI------------------------------
>UniRef50_A8EST1(4-239:273) Thiamine monophosphate kinase n=5 Tax=Epsilonproteobacteria RepID=A8EST1_ARCB4  E=2e-29 s/c=0.56 id=21% cov=31%
-------------------EEYFIKQFSNNKF-IGDDGAFIDG---------FVYSMDAFFENVHFKKEWmslkQIAYKSMIVNISDAIAMNARPLYALLSVAIPKSYSNEDLQELAKGFKKAASEFDIEIIGGDT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q03Y87(17-337:345) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Leuconostoc RepID=Q03Y87_LEUMM  E=3e-29 s/c=0.41 id=20% cov=46%
-----------GERAVDLMKDAVADTYNDQVL----DGIGGFGAAFALGKGYtdpvLISGADGVGTKLLLAIAADkhdtIGQDLVAMVANDILAQGAKPAFLLDYLAV-DKMRPEVVAEIVTGIAKAAKASNMSLIGGESAELPGLYAEKHYdLAAFAVGIAERQQLLSAKNVSEGDVLI---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B0S0R2(15-298:341) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=Bacteria RepID=PUR5_FINM2  E=3e-29 s/c=0.46 id=16% cov=50%
-----------GYEEVQIIKEIVKKTHGKEVLtGIGGFAGLFKPELTDMKEPVLVSGTDGVGTKIKLAMELDkhdtVGIDLVAMCVNDVLCQGAKPLFFLDYIA-TGSLKPAKMADLVRGVAEGCSQSECALIGGETAEMPGLYKENDYdLAGFAVGIVDRDKIIDGSGIKEGDVAISLSSSGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1ATX5(78-362:363) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Anaplasma centrale str. Israel RepID=D1ATX5_ANACI  E=3e-29 s/c=0.46 id=23% cov=69%
--------------------------------------------------------------------------------VNDILAQGATPLFFLDYFS-TGSLDYDTTLEVISGIAEGCRRADTALVGGETAEMPGMYPAGCYdLAGFAVGIVEKSEILPRtDQVRTGDVIIGLASSGLHSNGFSLVRKVLQDRNIAYDSPYPLADgvtwagiLLEPtriyvrpvLQVSQMIKAAAHITGGGLVHNIPRVLPES-LAANIQLGTWKqhsIFSWLEREAQIPATEMSETFNCGiGMVLIASEDAAGRVLQVL--GESGEDAYVIGSVVlrERHSVIL----------------------
>UniRef50_Q1QLI2(20-346:356) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=Bacteria RepID=PUR5_NITHX  E=3e-29 s/c=0.40 id=27% cov=71%
-----------------------------------------------------------------------IGIDLVAMSVNDLVVQGAEPLFFLDYFAC-GKLDPEVASAIVAGIAVGCREAGCALIGGETAEMPGLYKDGDYdLAGFAVGAAERGTLLPGRDIAAGDAVIGLASSGVHSNGYSLVRKIVEASGLGFSVPAPFAPVttlggalltptrlyvkscLRAIRETGAVKGLAHITGGGFTDNIPRVLPK-HLGIRIDLSRLTVLPVFKWLARQGGiaeLELLRTFNCGvGMIAIVRRDAVEQVVDVL--TQAGERVAPLGSVIEASG-------------------------
>UniRef50_Q01XD1(1-304:306) Selenophosphate synthase n=3 Tax=Bacteria RepID=Q01XD1_SOLUE   E=4e-29 s/c=0.43 id=20% cov=52%
-----------------------------------------------------------------------FGAIAAANSLSDVYAMGGRPISALSILAYPAKGDMDDLAAILKGGAEKMHEASCSILGGHSVNDEEVKFGY-----SVTGTVHPARVKANAGARAGDALVFTKRLGTGVIGTALKRGIARDEdvAEATASMLTLNRTACEEMLSYDVGGCTDVTGFGLIGHAREMAIASGVTLEIESDAL---------------------------------------------------------------------------------------
>UniRef50_A0YCF1(406-730:742) Selenide,water dikinase, putative n=1 Tax=marine gamma proteobacterium HTCC2143 RepID=A0YCF1_9GAMM  E=4e-29 s/c=0.40 id=21% cov=78%
------------------------------GLRSPDDAAVIN----PPEGRQWLQTVDyfrAFIDDPYL-----LGRIATNHCLSDIYAMGGTPHSALAIATVPYGSEeliENSLLQLMSGAVDSLNEQETSLIGGH-----SSEGAELGFGLSVNGTIAKNALLTKSNLHNGQVLVLTKPLGSGTLFAANMRgqaRGNWIDNALEQMLIS-NRQAASIIHQHGATACTDITGFGLLGHLLEMLNAtTNCSAQIIMDKLPILTGAAETTKAGWLSTLHPENSradqqlsnaeefsqhpfypllfdpqtaGGLLAALPSDQVDQCVAALRASDC-PDACVIGSI------------------------------
>UniRef50_C8S195(401-730:730) Pyridine nucleotide-disulfide oxidoreductase family protein n=1 Tax=Rhodobacter sp. SW2 RepID=C8S195_9RHOB  E=4e-29 s/c=0.40 id=26% cov=66%
----------------------------------------------------------------------------------DIWAMGAAPQVALAQITLPrmsPRMQAETLREIMAAASEVFRAEGADVVGGHTA-----TGAELTLGFTVTGLAK--RILAKGGARPGDALILTKPLG-TGTILAAEMAGQRAPglmlgeavvAALASMTRSLGP--DAAILTPQAHAMTDVTGFGLAGHLLEMLTASNCAAEISLPAIPLLPGAEALAATGAASSLAPANraactarmafndtpraallfdpqtAGGLLAAVPADQATALLTALHAA--NVRAAIIGQATEGaPFLTIKT--------------------
>UniRef50_O67691(424-715:745) Phosphoribosylformylglycinamidine synthase 2 n=6 Tax=Aquificales RepID=PURL_AQUAE  E=2e-21 s/c=0.36 id=18% cov=52%
------------------------------------------------------------------------GKFVVAEVCRNLACVGAKPLAITDCLNFGNPERPEIMWQFVKaveGMAEACEELGIPVVSGNVSLynetVEKNEIRNVFPTpiVVGVGVLEKAEKYTPSKVEKESELYLVGNLeenlrldGSEYLKVIHGLIKGDVPPVDLEKEKILINLLISFNNKELITCAHDVSVGGLLIALLEMVFRTPYGLEVE-------------------------------------------------------------------------------------------
>UniRef50_D2RQG9(3-296:307) Thiamine-monophosphate kinase n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2RQG9_9EURY  E=5e-29 s/c=0.45 id=25% cov=81%
-----------------------LSLLEGELEAAGDDAAVVDD---------LVITTDMLHERTDFPTGttrYTAGWRAVGASLSDVAAMGADATAAVAAYAAPE-FDRDELLAFVRGARDVCNRVDAAYVGGDL-----DGHSEFTVSTTAVG--RSDDPVRRSGAEPGDLLCVTGTLGRSAAGLELFGRSAREDSasdddsgvERANDLFRFEPRVAAGAALAPHATAMMDSSDGLARSLHQLAEASDCGFAVDSEAVPVAEALFELAdgEGTDADPLEraiaFGEDFELVATLPESALETVRAAI-----DVDLSVIGSVTEPvEGITLDGE-------------------
>UniRef50_B9L5P2(18-345:347) Selenide, water dikinase n=15 Tax=Bacteria RepID=B9L5P2_NAUPA   E=6e-29 s/c=0.40 id=20% cov=60%
--------------------------------------------------------------------------------------------------------DREVLKEILKGGEDKIKECGGVLAGGHTIETPE-MLYGLSVT----GVVNPKQMIRNNTLKKDDVIILTKPLGMGilTTAIKADLVSDEVASEVAEILRTLNYKASIIAREIGVSAMTDVTGFGLLGHLYEMSGK-KFTIEVEFDKVPFISEAINQASM-GIIPAGSYNnqifvekyvefvrnlsfeeqmilfdaqtSGGLLISLPQEKAEEYLK--RAGNEGVFAKIIGNVKEKEEKFIK---------------------
>UniRef50_D1JHF1(36-345:362) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=environmental samples RepID=D1JHF1_9ARCH  E=2e-28 s/c=0.41 id=19% cov=67%
--------------------------------------------------------------------------------VNDILCVGAEPISLVDYIALCEP-DPELLEEIGKGLLKGAEIANITISGGEIAIVKDMVKGvrknrEFDLVGTAVGTVSLDKVIVGANIQEKDVIIGLSSSGIHSNGLSLARHIFLKTGAIDEHFDVLEKtigaellepthiyvpeIMEMINSNLDIKALMHITGDGF---LNLTRVKSEVGFVIEylPETPPIFTLLQKRGNVTDEEMFRVYNMGiGFCVILPEQEAEVAIEIASRHK--VDAFRLGYVVKDP--------------------------
>UniRef50_Q97CD7(15-327:338) Phosphoribosylformylglycinamidine cyclo-ligase n=4 Tax=Thermoplasmatales RepID=PUR5_THEVO  E=3e-28 s/c=0.41 id=19% cov=86%
-----------GEFVSSFIRQLKFHREDFKNIGY----IGGFTSLIDMGNFALSFNNDGVGTKTMIAEQANkydtLGIDCVAMNVNDAITVGSEPIAMVDYLAV-RDLNEDIAKQLGNGFNVGAQIANISIVGGETAVVPE-IVNHIDVSGAVIGIVQKNQIITGANIKEGDVIIGLGSSGLHSNGFTTVRKIIsdneinlfdnfpgESKKTYEVLLEPTRIYVREILDVMGiiqIKGMANITGGGF----KNITRMKDMKYVIDDPMEPQNVFVR-LMELGNLNykqMYEIFNMGtGFVVVIGEDDKIDFINTLKNR---VPLKVIGHVENGTGV------------------------
>UniRef50_UPI0001C30E92(51-372:752) phosphoribosylformylglycinamidine synthase II n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C30E92  E=3e-28 s/c=0.40 id=21% cov=71%
------------------------------------------------------------------FQGAATG---VGGILRDIFAVGARPIAVLDSLRFGEvggddsARSRYLLEHAVGGIGHYGNSIGVPTVGGEIYFEPPYEQNCL-VNAMALGIAPHDRLTRSAATGPGNTLIlfgaLTGRDGIGGASVLASAELGEDDADKRPTVQIGDPFAEKkllecsleLLDEELLVSLQDLGAAGLTSSSSEMASKGGLGLDIHVDRVPVREPGMEPFEI-----MVSESQERMLCVVEPDKVDAVLAVCEKWE--TTATAIGEVTDSGRLRV----------------------
>UniRef50_C0C1G4(24-286:294) Putative uncharacterized protein n=1 Tax=Clostridium hylemonae DSM 15053 RepID=C0C1G4_9CLOT  E=3e-28 s/c=0.49 id=18% cov=76%
-----------------------------------------------------------------------IGVHALAESLNELAAAGAGAVEARVHIMIPDGYGRPRLAAVQKLIEKACGARGVTLIFLEQYKTPAAAL--PLVSVTCTGTAE----YTDRVIRPGQDIVLTKWAGLGGMVRILQEKEDELEERFAPAFIKQIKeyageifAGEELpaARQMGVSVFCQVTEGGIFAALWNLAREAETGLSVDMKKIPVRQETIEVCENYRLNPYQLMSAGSFLMVADNGR--ELAREL--TGRGMKAAVIGRMTDNNDKVIQNG-EEIRFIDRPAPDELNKI-
>UniRef50_D1B9N9(30-328:331) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Thermanaerovibrio acidaminovorans DSM 6589 RepID=D1B9N9_THEAS  E=3e-28 s/c=0.43 id=21% cov=66%
--------------------------------------------------------------------------------VNDLVTCGARPLFFLDYVAC-GSLDVEALSPILESIVESCEESGCILLGGETAEMPWvYPPQGFDLAGFAVGIVDIDQIVTGGNIEEGDLLLGLRSSGIHSNGYSLVRlaverarldltqpqpgFQLPLGEELLRPTKLYVRAAMEALSTRKVKGMAHITGGGLEGNVSRIIPR-GLRAQVDYSSWD-RPLIFRLLRELGIeeeEMRRVFNLGiGFVLVASPDHLPEVADAL--ARCGEEFIVIGRV------------------------------
>UniRef50_Q2RSC8(57-367:370) Phosphoribosylformylglycinamidine cyclo-ligase n=30 Tax=cellular organisms RepID=PUR5_RHORT  E=4e-28 s/c=0.41 id=25% cov=69%
--------------------------------------------------------------------------------VNDLVVQGGEPLLFLDYFA-TSRLQVPVASAVVKGIAEGCLQAGCALVGGETAEMPGMYGNNDYdLAGFAVGAVERSQLLTDDRIGLGDVLLGLASSGVHSNGFSLVRrivERSGLAWDAPAPFAPETTLARALLtptriyvksclalhRAGLVHGFAHITGGGFWENIPRVLPQ-GACAHLDGLSWPFPPVFRWLMDQGGVsahEMARTFNCGiGMVVAVPADKAEAAIALLGEH--GETVHRLGTIAargEGEAVIID---------------------
>UniRef50_A5UWC7(20-341:341) Phosphoribosylformylglycinamidine cyclo-ligase n=6 Tax=Bacteria RepID=A5UWC7_ROSS1  E=5e-28 s/c=0.39 id=24% cov=68%
----------------------------------------------------------------------------VNHCVNDILVQGARPLFLLDYLAV-DRLDPQRAATLVASVAAACREVGCVLLGGETAQMPDVYREGAFeLAGTIVGVVRRAQMLPRNVA-AGDVILALPSSGLHTNGYSLARRVLGRGSAWGYDARPaelngrsigeallephrvyLRAFEQLEAAGVAVHAMAHITGGGIYENLPRVLPE-GCGAVIRRRTWTIPPIctlVVQAAGLDEREAFRTLNMGlGMLVIVPSDAADAARRAV------PEASPVGEVVTGGDVRL----------------------
>UniRef50_A8EUZ4(15-337:345) Selenide, water dikinase n=2 Tax=Campylobacterales RepID=SELD_ARCB4   E=7e-28 s/c=0.39 id=23% cov=74%
----------------------------------------------INESQAIVQTLDfitPVVDDPYIY-----GQIAAANALSDVFAMGAEVKTAMNIVGFDrKNIPKDALEMILDGGNSKIKECGGVLLGGHTIESPEMYY-----GLSVTGMIHPNEIIRNNTPKIGHVLVLTKPIGMGILTTAIKRDLLEL--NLIKDCakimASLNYLPSKMMRKYEVSSCTDITGFGLMGHALECTNNSitlnishndvpfvkeafdfasndvipggtRRNMKYVEDKIEFLPNVSDIYKALLCDAQTS---GGLLIAMKKDDAKEFIKELEDYSFGY-ASIIGEVIPR---------------------------
>UniRef50_B3V643(410-708:734) Phosphoribosylformylglycinamidine synthase synthetase subunit n=1 Tax=uncultured marine crenarchaeote KM3-153-F8 RepID=B3V643_9ARCH  E=2e-14 s/c=0.28 id=13% cov=31%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLVRDAIKVKLLGAVNDCSKGGFIHSLSQMCMVGNVGVTVDMSK------ILTSCKRWD-DVLFSESHSRFITTIKPEHYNNLLNI--SRNYNIPISVIGNVGGNELRIMDN--------------------
>UniRef50_Q83FJ9(37-330:337) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Tropheryma whipplei RepID=Q83FJ9_TROWT  E=1e-27 s/c=0.43 id=23% cov=69%
-----------------------------------------------------------------------IGQDLVAMVVGDIAVVGGKPLFMTDYIACGELIP-ERIAQIVGGVARACQEIDCVLLGGETAEHPEvMARNQYDLAGAATGVVEASDLLGKDKVKTGDVLIGVASSGLHANGFSLVRKicrdvsfaeycpdlQTTWGEALLEPTRMYVNLIRDLIKTGKLHAASHITGGGIPGNLPRILPE-GLGARLH--PWPIPDLFKVLCEFGSLSLSEVKNAwnlGIGLIIVASST-----SILEDIDDSWQARLIGEVIDGE--------------------------
>UniRef50_D1ZBE4(422-745:762) Whole genome shotgun sequence assembly, scaffold_16 n=1 Tax=Sordaria macrospora RepID=D1ZBE4_SORMA  E=1e-27 s/c=0.39 id=24% cov=68%
--------------------------------------------------------------------------------VNDLVVQGAEPFMFLDYYGCSR-LDVSVAAAFVEGVAQGCKDAGCALVGGETAEMPDlYTGDDYDAAGAAIGVMKAAQRLPRKDAmAEGDVLVALASSGVHSNGFSLVRKVVDKcglsytdkapwdssasvgESLLTPTRIYVKPLLKVLAQTGeAVKGMAHITGGGLTENVPRMLPK-HLAAEIDVATWEHPPVFKWLREsVIPTEMARTFNNGiGMVLAVAPETADAVVKGLEAE--GEKVYTIGKLVNREG-------------------------
>UniRef50_D2L8W8(45-308:322) AIR synthase related protein n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L8W8_9DELT  E=2e-27 s/c=0.47 id=19% cov=66%
------------------------------------------------------------------------GRCAVLANINDIYAMGGRPLAMVDVVGTP---DEATAREICRGMRDAAARYRVPVVGGHLLRTAFDHSA----SMAILGRAKT--CLTSFDARPGDSLVLaTRPNGAWLGDLGFWNATLpEDDATLIAHLELLPACAEAGLARAG----KDVSMAGLAGTALMLAESSGVGCRLDVDALSPPPGAP-------LTPWLLAFMsYGFLLAVAPDKLDAVVALFTA--GGVRTVPVGEVCRERQVWL----------------------
>UniRef50_B0N3F7(167-417:426) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=Bacteria RepID=B0N3F7_9FIRM  E=2e-27 s/c=0.50 id=20% cov=29%
--------------------------------------------------------------------------------VNDIVVMGAKPLAVLDTIVC-GNAEKETIASLVKGISQACQNNECSLVGGETSIQPQVVEHGVYVlTSSIAGIVAKDKVIDGSKISAGDVILAIASNGLH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B3E0M2(495-742:762) Phosphoribosylformylglycinamidinesynthase, synthetase domain n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3E0M2_METI4  E=4e-19 s/c=0.40 id=22% cov=65%
-----------------------------------------------------------------------------------LAVVGAIPLGITDNLNFadpNDPFSYWQFKEAVRGIAEACRFFEIPVTGGNVSFYNFSKQSSILPTPVigAVGLIETDKALAKMAFQnPGDVIVLLGGWGNGLEGSLYLQEYFGESGQKLPHFSLEaekkhNELLYSLANEGIASSIHDLSEGGLGLALVECsvSGDKKLGFSISLPA------------ELRLDELLFNEAGaRSVVSLPGENLSSLLKI--AEGKGVQGIVLGEVTEEYFLKLR---------------------
>UniRef50_UPI000050FADA(10-350:362) thiamine monophosphate kinase n=1 Tax=Brevibacterium linens BL2 RepID=UPI000050FADA  E=4e-27 s/c=0.36 id=22% cov=62%
-----------------------------VIIGPGDDAAV------TAVDGNLVSTADMLVENEDFTRTWldwsRLGTKAAAQNLSDVCVMGAKPHGLLVSLAVPNSTEIEDLEALFAGIVAEAARAGealgceIPIIGGDLS-----SSGLIVVAITALgtvggsgtgtaassaGTHGSGAAITRAGAQPGDSIYLAGTIGRAAAGLDLLFAGVDPNADVgQDDPQPGTSLTELIntqlapqpdyaavLEMRAASAMIDVSD-GLSTDLGRVAAASGVHACIDRTA----------------------------------------------------------------------------------------
>UniRef50_D1B9U1(11-342:344) Selenide, water dikinase n=3 Tax=Synergistaceae RepID=D1B9U1_THEAS   E=4e-27 s/c=0.37 id=20% cov=82%
----------------------------DPNLLSGWDN-GEDAALWRIGEGRLAIlTVDFIT--PIVDDPLTFGEIAAANSLSDVFAMGGSPKVALNLVAFPTSCePLEVLSQILEGGARKVMEAGACLAGGHSVQDEEPKY-----GLSVYGEVDEGGLWRVTGAREGDSLILTKPVGsgiITTASKGGVAEGDWLDQAVQ-WMRMLNNVPGRMDRslLGNVRAATDVTGFGLLGHCMDMLSHRELDLVIHHDQVPfidgafqmasmgmvpagaysnrghvehrvlMSPNVPLAVQDILFDPQTS---GGLLLAVAPGSEKEVLSQLWELGFHRAATV-GRFIKGEGKVL----------------------
>UniRef50_B5IIZ7(33-317:359) Thiamine-monophosphate kinase n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5IIZ7_9CHRO  E=2e-26 s/c=0.43 id=23% cov=41%
-----------------------------------DDAAVLDLGDSR--GHGLVVNTDVLVEDVHFSAattePFHVGWRAAAANLSDLAAMGCTgASGLTVGLIAPASTRWSWVEAVYGGLGRCLSAHG----GGNLLGGDCSSGRQRILAVTALGTLAAAGPIRRTDGRPGDALVCTGPHG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2A162(41-362:368) AIR synthase related protein domain protein n=3 Tax=Clostridia RepID=B2A162_NATTJ  E=2e-26 s/c=0.38 id=27% cov=46%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------EAGDKIIIIGETGVDGNDTL-------YRAGLVSELLPAQALFEEekttmeatlsAFKTGKVKACSDLGAAGIGAAVCESARFGGLGAEVELDKAPVKTE-----NISPEERLICETQGRMLLQVAPENVDEVLEAISA--KNGQGAVIGEITAENQSIFK--YQGERIAtipNQPSDEIL----
>UniRef50_B0SB88(78-370:748) Phosphoribosylformylglycinamidine synthase 2 n=6 Tax=Leptospira RepID=PURL_LEPBA  E=2e-26 s/c=0.41 id=15% cov=25%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GISCATSEMSAKGKTGMDVDLDKVPLRE-----ADMNAYEIMLSESQERMLVIPEVGKEGELVSIF--HKWGLNAVEIGTVTADGILRIR---------------------
>UniRef50_A9A5G5(413-701:721) Phosphoribosylformylglycinamidine synthase II n=4 Tax=Thaumarchaeota RepID=A9A5G5_NITMS  E=1e-15 s/c=0.30 id=20% cov=29%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKSVHDCSKGGLAVAVSELSMNNQIGCKVDLDKVP--------AKKLDVDrILFSESHSRYLLTFDKKNLSKVEKILKKNKTSYN--IIGQF---GGEKIQFTKGKKSIIDL----------
>UniRef50_Q4JXF0(67-368:813) Phosphoribosylformylglycinamidine synthase 2 n=100 Tax=root RepID=PURL_CORJK  E=3e-26 s/c=0.40 id=19% cov=69%
----------------------------------------------------------------------------VGGIVRDIMAMGARPVAVMDQLRFgPADLPDtqRVLPGVVAGVGGYGNSLGLPNIGGETVFDATYAGNPL-VNALCVGTLKTEDLKLAFASGKGNRVILfgsrTGLDGIGGVSVLASDtfeegAERKLPAVQVGDPFAEKVLIECCLDLYRanvVVGIQDLGGAGLSCATAELASAGDGGMHINLDNVHLRAEGMTAAEI-----LSSESQERMCAVVEPENVDAFMEICRK--WDVLASDIGCVTDGEHLVIE---------------------
>UniRef50_Q4JXF0(432-774:813) Phosphoribosylformylglycinamidine synthase 2 n=100 Tax=root RepID=PURL_CORJK  E=8e-13 s/c=0.23 id=20% cov=66%
--------------SREFITEQYDRYVRGNTVAAKDADAGV-LRIDEETGRGIAVSTDASGRYARLDPRTG-AQLALAEAYRNVSVTGATPVAVSNCLNFgsPEDPGVMWqFREAVHGLADGCKEMGIPVTGGNVSFYNQTGDTAILPTpvIAVLGTIDdcarriPQQLPKQAGAEAGadesqeqyHLVLV-------GAETREELGGSIWQQVVHDELAGLPPQVDLSVEQRlgafitdqrdKIVAAHDLSEGGLSQAVVELAIQSGRGMAV--------------------------------------------------------------------------------------------
>UniRef50_D1AYX0(23-326:331) Phosphoribosylformylglycinamidine cyclo-ligase n=8 Tax=Campylobacterales RepID=D1AYX0_SULD5  E=2e-25 s/c=0.39 id=19% cov=65%
---------------------------------------------------------------------------------NDLICNFGTPLFFLDYYAMSK-LEIDASVNIVKGIAEGCKEAECSLIGGETAEMPGMYHGKDFdLAGFAVGIAEKDEMNRLPHVKAGDVLIALPSSGVHSNGFSLVRKiffdklGYTFETEFNGKPliktlltptRIYVKLFKALKE--KINALAHITGGGIVENLPRVLPE-GLQARVYTSKIKTLPIFDFMSQyVEESEMHRTFNMGvGMILVVSPENVDAVLNS-------SDGYVIGELTEGE--------------------------
>UniRef50_C7M1V9(424-714:734) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M1V9_ACIFD  E=1e-11 s/c=0.25 id=23% cov=31%
--------------------------FRTSLVEPGADAALLRVrtPEVGDTGRAIAITVDGNNRWTRVDPRHGATWL-VAEGVANLACVGATPLALVDCLNFgnPEHPTVMWqLAESIDGIAEAARALGVPVVGG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6BF49(24-314:338) Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM 13814 RepID=A6BF49_9FIRM  E=2e-25 s/c=0.41 id=22% cov=54%
----------------------------------------------------------------------------------------------------------------------------------------------IAVTVTGIAKAPKEEAWNRETARACRDIVFVGHAGMDG----MLRITEEKEQELKTRFAPVfmkqiklygqqifAPKEIEAAKAGGAFVVRQVADGGILAALWNLALELNQGLDLDMKKISILQETIEVCEHFRLNPYQMISTGSFLAVT--DNGEVLADAL--NNQGITAAVIGHTTDNNDKILRNG-EEMRYIDRPAPD------
>UniRef50_D0MSK9(54-375:392) Selenide, water dikinase, putative n=1 Tax=Phytophthora infestans T30-4 RepID=D0MSK9_PHYIN  E=2e-25 s/c=0.37 id=19% cov=80%
-----------------------------PNETPGMDSSVVKISH--GTDLYLVSTTDFFfpsVEDPYVQ-----GKIACANVLSDAYAMGVTEVdTMLMILGVCRDMSEKQRDvvttQMIRGFNDLARQACTNVTGGQTVMNP-----WPIVGGVAMSVRSESQIIRPENAAVGDVIILTKPLGTQVAVnLFQWKKRPDRWQRVEnvvthkdADVAfqmasesmsRLNLNAAKMMHKYGAHSATDVTGFGIVAHARNQAKSqlGDVSFEIHT--LPIIKNMAKVNEAIGnsfklLDGFAAETSGGLLLCLPAESADAFIKEIRELD-GKPAWVVGRVVAGSK-------------------------
>UniRef50_A1RYZ9(25-290:465) AIR synthase related protein domain protein n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RYZ9_THEPD  E=6e-25 s/c=0.44 id=24% cov=57%
-------------------------------------------------------------------------------SASNLAVSFARPELAVLSAVFPEGYPGEAVERVLRSFVEECRKYGTRLVGGHTARYR--GLELPLLSSTMVGRAGR----RREKPAGGDRVVIVGEVGAEAAWLAG--------GDVDPSTLTPLPAALALQEEPSIKLMHDVSEGGVIGALLEVAQRYGVALEVSSRDVKVFEGLPR-----GVEPLSAPSYGAIIAVT--GDAESLLSA----------------------------------------------
>UniRef50_D2NR50(53-383:414) Phosphoribosylaminoimidazole synthetase n=1 Tax=Rothia mucilaginosa DY-18 RepID=D2NR50_9MICC  E=4e-24 s/c=0.34 id=22% cov=86%
----------------ELMKGAIKATHNSSVVGGVGGFAGLYDVSelVKYRKPYLATSTDGVGTKVAIAQALDihdtIGYDLVGMVVDDIVVCGAKPLFMTDYIATGKVVP-ERIADIVRGIAGACAQAGTALVGGETAEHPGlLAEDEYDVAGAATGLVEADELLGPDRVREGDVLIAMASSGIHSNGYSLVRKVLNVAGWgLERQVDELGRTIgEELLEptrvyaadcldlaaafpvngedgttGSGVRGFSHVTGGGLAANLARVLPQ-GLEGRVDRSTWQIPAIFSLIGSLGNVplaDLERTLNLGvGMIAIVDPSVAEAATKRL--NDRGIPSWIMGDVV-----------------------------
>UniRef50_C1TMB6(9-275:278) Selenium donor protein n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TMB6_9BACT  E=8e-24 s/c=0.42 id=19% cov=47%
------------------------------------------------------------------------------------------------------------------------------------------------------GEVEKDALWKTTGADPGDLLILTKPLG-SGIIATAVKADMVDDPVWAEDatkwMSKLNDLPLKMARsmRKAIKSCTDVTGFGLAGHCLDMLSTKKVNLELKSEKLPLMDGALELASMgllpagaytnrslyegrvegldsmgeradFLFDPQTS---GGLLLTVSPDKSEELMELAIENGFEKTA-VIGRFKDGDGRI-----------------------
>UniRef50_A8A992(70-318:319) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8A992_IGNH4  E=8e-24 s/c=0.45 id=23% cov=66%
---------------------------------------------------------------------------------NDVACEGFRVFAYVDYLAVERGDPV-LAREVAEGMSKAAEALGAVLAGGETAIMP-DVVKGYDVSCTVLGVREA----RPQPPRPGDAVIAVASNGPHANGYTLIRRliqagLLDPEPLLDFLLAPVanyhNPLLRAMKE-GKAKWGAHVTGGAFYKVHSRLPKGLGV----RLEAWEVPEGFVKIVEAAGMsaeEAYKTFNMGVGMLVV---GSEEAVEAFERE--GLKAWKAGEVVEGP-TEIETPWG-----------------
>UniRef50_A0B5C7(435-736:768) Phosphoribosylformylglycinamidine synthase 2 n=1 Tax=Methanosaeta thermophila PT RepID=PURL_METTP  E=1e-14 s/c=0.27 id=21% cov=52%
------------------------------------------------------------------------GATAVAEAMRNVAAIGATPSTLTDCLNFGNPEKPEAFWEFresVRGLADAARNLwlkghpnqPVPIVSGNVSFYNESPEGAVDPSpvIACVGIMRDiSRAITMSLKEAGDGLYLLGPRFDELGGSEYYRLIWGVTGANVPVVRFPLERsmiytVIDAVDREILRAAHDISNGGMAITAAEMCMLSDHGISID-------------------------------------------------------------------------------------------
>UniRef50_A4FVZ3(48-318:327) AIR synthase related protein n=7 Tax=Methanococcus RepID=A4FVZ3_METM5  E=2e-23 s/c=0.41 id=18% cov=50%
---------------------------------------------------------------------------------------------------------------------------GIPVVGGHT--HPDAQCNVLDISIT--GLVKRDNVLRSDAAKTGDKIVFAYDLDgkIHETFNLNWDTTSMKSKKYVRDQL---KVLEIIGEEHLANSCKDISNPGGLGTLGMLLEVSKKGAMVDVSKIPVPEDVSL------NHWLKMYPGSGFVFTAPENKTKDLIERLEFT--GIASAVCGEV------------------------------
>UniRef50_D2S093(19-335:345) Selenide, water dikinase n=1 Tax=Haloterrigena turkmenica DSM 5511 RepID=D2S093_9EURY  E=2e-23 s/c=0.35 id=21% cov=88%
-------HGCSCKVGRSDLDDLLREAGLTESRDELLFGVGEDAAARqLTDDLALVSTVDFFT--PIIDDPYDFGRVAACNAASDAFATGAVdNLDCLAVLGLPQELTTA-APMILAGIADAIDGMGGVVAGGHTIISP-----WPFAGGAVSATAPPEELLTSQRATTGDRLYLTKPLGTQSAMGALRVSDDEFvDVVAEAAGRSVRTIGDEAVAwmttpnraaavaaRDVASAATDITGFGLVGQAEVLADNADVGIEV--TRLPVIEGTEGLSALFGYGLEDGESaetSGGLLLSVPPSHTATLESRL--DDAGVFYRQIGRVTDGDGVSLR---------------------
>UniRef50_C4G443(64-322:325) Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4G443_ABIDE  E=3e-23 s/c=0.43 id=21% cov=54%
----------------------------------------------------------------------------------------------------------------------------------------------VFISGKGCLKKTSDAPWQRQRIFEGQRIILTGSVGKSGMIELFDKNKQDLKqiypdiyiEKMSNKSADRLPYAEtETAPFYKVSAMLPLGPGGLTAGLWNLGEREEAGLVIYADRINYEQETIEISNHFNLNPLELNSEGAYLLATDRG--EELTLALRSA--GIDAVCIGEVTKNKKRVVMFED-EERYIESPG--------
>UniRef50_A4BDG5(391-698:705) Selenide, water dikinase, putative n=1 Tax=Reinekea blandensis MED297 RepID=A4BDG5_9GAMM  E=7e-23 s/c=0.36 id=22% cov=66%
------------------------------------------------------------------------GIVSVHHAVNDSYAMGLAPssaqVWINLAFSHPR-LARRDFKWLMHGVHDALREHDARLIGGHST---EGAETHMAVVVNAEGQAR----WPKRGAQPGDWLMLNRPIG-TGILLAADMAGSAHPADIESLWQHLltsnRDFFEALADTP-VNAATDITGFGLIGHVLEMMADTSTSAVIEVDTVPLLPGAHELSKqgvqstlLPQLEPLLRDCqierptdarlrclldpqtQGGLLVSVSPEHGQSLLDA------GL-ATRIGQVRERQ--------------------------
>UniRef50_C1A8F1(62-347:350) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Gemmatimonas aurantiaca T-27 RepID=C1A8F1_GEMAT  E=1e-22 s/c=0.38 id=22% cov=47%
-----------------------------------------------------------------------IGHCLVNHCTNDILVQGAVPLYFLDYVAF-GKLEPAVVEGVVAGVAAGCRENLCALIGGETAEMPGVYTPPDYdLAGFITGIVEEDQVLSSVRVEEGDVLVALASDGLHTNGYSLARRIIsdrlnlgvhdlfpDADGASVADVmlkvhRSYLTCLQPLL--GSIHAMAHITGGGLPGNLN--------------------------------------------------------------------------------------------------------
>UniRef50_Q5T5U9(28-300:321) Selenophosphate synthetase 1 n=2 Tax=Eutheria RepID=Q5T5U9_HUMAN   E=2e-22 s/c=0.40 id=20% cov=68%
-----------------------------PRLGIGMDTCVIP---LRHGGLSLVQTTDyiyPIVDDPYM-----MGRIACANVLSDLYAMGVTECDnMLMLLGVSNKMTDRERDKvmplIIQGFKDAAEEAGTSVTGGQTVLNP-----WIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGT------------------------------------QVAVAVHQ-----WLDIPEKWNKIKLVVT--------QEDVELAYQEAMMNMARLNRTGGLLICLPREQAARFCAEIKSPKYGEghQAWIIGIVEKGNR--------TARIIDKPR--------
>UniRef50_A5UWJ5(696-966:985) Phosphoribosylformylglycinamidine synthase II n=6 Tax=Chloroflexi (class) RepID=A5UWJ5_ROSS1  E=2e-12 s/c=0.28 id=29% cov=29%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRACHDLSEGGLGVAVAEMALAGNLGVTLDVRAVSHNP-----AAADDLVLLFSESPTRFLVEVRPADASAFEAAMTGHA----CARVGTVTEA-DVAITGLMGET---------------
>UniRef50_P00967(799-1127:1353) Phosphoribosylglycinamide formyltransferase n=19 Tax=cellular organisms RepID=PUR2_DROME  E=5e-21 s/c=0.32 id=23% cov=67%
--------------------------------------------------------------------------------VNDILCNGAEPISFS-SYYACGHWQEQLAKGVHSGVQEGARQANSSFIDSHSAALPLLYEPQVYdLAGFALGIAEHTGILPLLAeIQPGDVLIGLPSSGVHSNGFSlvhavLKRVGLGLhdkapfsdktlgEELLVPTKIYVKALSTLLSRGKhGIKALAHITGGGLSENIPRVLRK-DLAVRLDANKFQLPPVFAWLAAAGNIsstELQRTYNCGlGMVLVVAPTEVEDVLKELR---YPQRAAVVGEVVARK--------------------------
>UniRef50_A8XC59(475-815:1019) Putative uncharacterized protein n=2 Tax=Caenorhabditis briggsae RepID=A8XC59_CAEBR  E=2e-20 s/c=0.30 id=19% cov=44%
--------------------------------------------------------------------------------VNDVICHCAKPIAFLDYFVC-GKLDRSMATQVLASISDACVEAECSLIgkllnygkkdarfsiklfaGGETAEMPGvYSTHQWDLAGCAIAAREStwPMLPLLTSIQEGDVIIGLPSSGLHSNGFSLARkvltangveysvklpwdETKTFGDELLTGTKLYVKTVLPLLTDGLVKGCAHITGGGL-------------------------------------------------------------------------------------------------------------
>UniRef50_UPI000194E500(444-741:1015) PREDICTED: phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase n=1 Tax=Taeniopygia guttata RepID=UPI000194E500  E=3e-20 s/c=0.34 id=25% cov=30%
--------------------------------------------------------------------------------VNDLLAQGAEPLFFLSHLAC-GKLNAEVMETIKEGIAEACRSAGCAFLGAEvTEVAAPCPPGHCDLAGFAVGAVERGQRLPGlQRAEEGDALLGLGSAAIHG------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5WW17(72-395:780) Phosphoribosylformylglycinamidine synthase II (FGAM synthase II) n=5 Tax=Legionella RepID=Q5WW17_LEGPL  E=3e-20 s/c=0.31 id=26% cov=28%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDLGAGGVACASIELAEAGGsYGAEIDLDKVPT-----GMPGLMPSVILCSETQERFMWVVPPDLVDTILKhynetfALPQVSEGARAAVIGKIRTD-GLYVVNYKG-----------------
>UniRef50_Q0CH68(514-794:815) Phosphoribosylformylglycinamidine cyclo-ligase n=17 Tax=cellular organisms RepID=Q0CH68_ASPTN  E=7e-20 s/c=0.36 id=30% cov=29%
--------------------------------------------------------------------------------VNDLVVQGAEPLFFLDCYSC-GKLDVNTASAFVTGVANGCVQAGCALIGGETAEMPGLFVEDTYdavgaavgaINTT--GEHARTVLPDTAAMRSGDVLLALASSGPH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D2R8C5(252-576:981) Phosphoribosylformylglycinamidine synthase II n=6 Tax=Planctomycetaceae RepID=D2R8C5_9PLAN  E=3e-18 s/c=0.29 id=22% cov=69%
--------------------------------------------------------------------GANTG---VGGVIRDTLGTglGAKPLCNTDVFCfadpstpveeLPPGVlhPRRIMRGVVAGVRDYGNRMGIPTVNGALYFDRRYVGNPLVFCGN-VGLVPKDKAF--KETQPGDLIVAmggrTGRDGIHGATFSSVELTSQSEKVSGGAVQIGNAITEKMvldvllraRDEELFTAVTDCGAGGFSSAVGEM--GADIGAEVWLDRCPLKYDGLTYTEV-----WISEAQERMVLSVPEEKWPQLEALCKSED--VEATVIGRFTPTGRLKLK---------------------
>UniRef50_Q7V2Z5(377-619:730) Selenide,water dikinase n=8 Tax=Prochlorococcus marinus RepID=Q7V2Z5_PROMP  E=4e-18 s/c=0.39 id=22% cov=38%
----------------------------------------------------------------------------------------------------------------LKGIKTTVEEQGGKLIGGHTfesrSLVDQPYSLGIDISLTVQGVLKNGaKPWLKSGMKKGDIILMSRPLGV-GIFFAAQMQNINLKDsseeimrNLVTSQQPLIDKIYLLQDKFGetfINAATDVTGYGFIGHLKEMIDSSNL------------------------------------------------------------------------------------------------
>UniRef50_Q73N76(82-402:766) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Treponema denticola RepID=Q73N76_TREDE  E=1e-16 s/c=0.28 id=24% cov=72%
------------------------------------------------------------------FGGANTG---VGGVIRDV--MGvsARPFAVTDVLcfghpdtpaeNVPKGTlhPKRIISGVIEGVKDYGNKMGIPTVNGGVHYHEAYASNPLVYCG-CAGIAPRGK--HRTKPSAGDHIISlggkTGRDGLRGATFSSMVMDASTGDVAGSSVQIGEPIIQKkvaevlidARDQGLYSAITDCGAGGYSSAVGEMASA--LGCDVDLAKIPV-----KYQGLAPWELWLSEAQERMVIAVPNDKLEALQKLCDAND--VELTNLGRFTGDA--VLRVRFGEKEIINL----------
>UniRef50_Q2Q0E4(666-982:1008) Phosphoribosylformylglycinamidine synthase II n=1 Tax=uncultured organism HF10_3D09 RepID=Q2Q0E4_9ZZZZ  E=9e-11 s/c=0.22 id=19% cov=84%
---------------HEVIAQTVVKPFVGVERDGPGDAGLI--APIHGNPQGLVVS---CGIAPR-YSDIDAGAM-VAASI-DEAVRNAVCVGVdidkmagLDNFCWPDPIESEktpdgkfKLAQLVranRELERVCRAYRLPCVSGkDSMKNDYGVWpNKISIPPTMLfslfGNQPDVRKTATSNFKRhGERIYLVGTtyeeLGASEVAFHLRERGDATGiGGQVPRLEDPVRQLEVYRKLSSsiqnglIRTAHDCSEGGLAVALAEMCIGGRCGAIIDID---------GIGSCDVFSRLWSESLGRIIVSVEAEHELAFVEMME----GADIHLIGMVTESPNLIVEDGY------------------
>UniRef50_B1I460(312-562:947) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Peptococcaceae RepID=B1I460_DESAP  E=5e-16 s/c=0.35 id=24% cov=34%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDAILEARDQNLIRAITDCGAGGFASAAGEM--GADTGVLLALDRAPL-----KYSGLAPWEILLSESQERMVAAVAPENLELFMDVCRR--LNVEATLIGEFTGD--RRFRATFHGETVLDL----------
>UniRef50_Q8MXD3(60-411:413) Selenophosphate synthetase (Fragment) n=8 Tax=Trypanosomatidae RepID=Q8MXD3_LEIMA  E=5e-16 s/c=0.25 id=21% cov=79%
----------------------------------GMDCSIVPLHHTNSKGEAlfLVSTTDFFFpsVSDPFLQ----GQIGAANVLSDLYSMG-IPDCdtMLMLLAASTEMDEHERlittREIMKGFAERARLATTTVTGGQTVMNP-----WPLIGGVAMAVVSEAEMVRPTGlLCAGDILVLTKPLGCQVAVNLkqwLLRPSPLYEEAIAGHispeeieelynmatdsMRRLNREGARLMRKHGAHGATDVTGFGILGHANNFGAAQAVGdaprsLCLVLERLPMFKTAVAASKQMNdkyrlLEGYSAETSGGLLVAFPStTAAAAFCAELTAVDGGCPSWIVGHVEDR---------------------------
>UniRef50_C0F9P1(304-601:1035) Phosphoribosylformylglycinamidine synthase II domain protein n=1 Tax=Wolbachia endosymbiont of Muscidifurax uniraptor RepID=C0F9P1_9RICK  E=8e-15 s/c=0.28 id=18% cov=49%
-----------------------------------------------------------------------------------------------------------------------------------------------------VGIIPRNInnaPSHIKGPKNGDKIVIiggrVGRDGIHGATFSSEALSGNSPSTIVqiGDPITQKKLSNAALEARDLDLYNAITDNGAGGLSSSIGEMGKDGFEVDLSKVLLKNDGMAPWEI-----WISESQERMTLAVPEENLPMFKQIMKKHD--VEVCVIGEFNESGKAVVKCPKG-----------------
>UniRef50_Q5GT14(328-639:1045) Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain n=19 Tax=Rickettsiales RepID=Q5GT14_WOLTR  E=1e-14 s/c=0.27 id=22% cov=44%
-----------------------------------------------------------------------------------------------------------------------------------------------------VGIIPRNINNAPSHIKKpqnGDKIVIiggrVGRDGIHGATFSSEALSGNSPSTVVqiGDPITQKKLsnaVIEARDLGLYNAITDNGAGGLSSSIGEMGKD---GFEVDLSKVLLKSDGMAPWEI-----WISESQERMTLAVPEENLPMFKQIMKKHD--VEVSVIGE-------------------------------
>UniRef50_C6PLR7(1-197:212) AIR synthase related protein domain protein n=1 Tax=Thermoanaerobacter italicus Ab9 RepID=C6PLR7_9THEO  E=2e-12 s/c=0.39 id=27% cov=33%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQELVLKLIDEGLIKSSHDISEGGFAAALVESAIAGKKGAKISL-QTSLREDVELFSE----------SQSRALITASPEKVDEVLKI--AYEYQVPAQKVG-VVEGKDIVID--VNGKRIIDLP---------
>UniRef50_P38972(374-640:1358) Phosphoribosylformylglycinamidine synthase n=34 Tax=cellular organisms RepID=PUR4_YEAST  E=5e-12 s/c=0.28 id=15% cov=51%
----------------------------------------------------------------------------------------------------------------------------------------------------GFGTVRPQFALKNTPITPGSCLIVLGGqsmlIGLGGGAASSVASGEGSadldfasvqrgNPEMERRCQQVIDACVALGNNNPIQSIHDVGAGGLSNALPELVHDNDLGAKFDIRKVLSLEPGMSPMEI-----WCNESQERYVLGVSPQDLSIFEEICKRERA--PFAVVGHATAEQKLIVEDPLLKTTPIDL----------
>UniRef50_Q7RD94(521-928:959) Selenophosphate synthetase n=4 Tax=Plasmodium (Vinckeia) RepID=Q7RD94_PLAYO  E=2e-11 s/c=0.18 id=17% cov=66%
--------------------------------------------------------------------------------LSDIYSMGGTGICALCVLIIKDNIEkklQQRLENILTGCCQKLKEEKCVLSGGHTCAGTENYV-GLAVTGKIkkkknnnkdkeeirksqnnesvldktnqVGnnsinkvneLNEAYHFLPKGSIevKPGDVIITTKVFGFGFimAAHISKKAKARWIYNCLDEMLISNRKGGLYFLKNNAKACTDVTGFGILGHLNEMIKCSRreyyikcvsnnisnneinqkgndnkcneldninfIGAKINLNKINIAEGVQEciqnniyssmykknhylcnniinldeaiLNDKYGilFDPQTS---GGLMAIVEREHANTILSDLKNMGY-QNSSIIGEII-----------------------------
>UniRef50_Q0CAP5(411-635:1364) Phosphoribosylformylglycinamidine synthase n=72 Tax=cellular organisms RepID=Q0CAP5_ASPTN  E=1e-08 s/c=0.28 id=23% cov=24%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IKFIHDVGAGGLSNALPELIHDSGLGAtfelrEIDSADKSMSPMQIWCCEA----------QERYVLAVGEDGMNKFTAIANRERCGF--SVVGR-------------------------------
>UniRef50_Q6AQE0(352-574:1267) Probable phosphoribosylformylglycinamidine synthase n=1 Tax=Desulfotalea psychrophila RepID=Q6AQE0_DESPS  E=1e-06 s/c=0.25 id=17% cov=28%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGPANVIKELVEKSGGRVDIR--KIQVGDPTMSVLEI-----YVAEYQERCGFLIRPENIEQFENICKREKVG--CEILGEVTGDLRFVLFDSENGTTPVD-----------
>UniRef50_Q8BEM8(755-977:1321) ORF65 n=1 Tax=Callitrichine herpesvirus 3 RepID=Q8BEM8_9GAMA   E=0.0001 s/c=0.22 id=29% cov=27%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IKELMALGMVESGHDVSDGGVLVCAIEMALAGNRGIKI---SVPEDQDIME--EMFSEAP-------GVIFEVHRAHAERALKELQGRQL--RAFQIGAVGEEG--------------------------
>UniRef50_Q3KSV4(742-973:1318) Major tegument protein n=6 Tax=Lymphocryptovirus RepID=MTP_EBVG   E=0.0002 s/c=0.21 id=28% cov=22%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HDISDGGLVTCLVEMALAGQRGVTI---TMPVASD--YLPEMFAEHP-------GLVFEVEERSVGEVLQTLRS--MNMYPAVLGRV------------------------------
>UniRef50_B7JZ80(17-348:348) Hydrogenase expression/formation protein HypE n=17 Tax=Bacteria RepID=B7JZ80_CYAP8  E=4e-80 s/c=0.90 id=47% cov=98%
--QVLLAHGGGGKLMQQLLEKMFFPAFKTTHNIPPHDSAVL-----SLNTNKIAFTTDSYVIHPLFFPGGDIGSLAINGTVNDLAMSGARPLYLSVGFILEEGLPMETLWRVVQSLQKAAQIAEVQIITGDTKVVDHGKGDGIFINTAGVGIVEHNQVIAPQSVQPGDAILISGDLGRHGIAIMAVREGLEFETAIESDCAPLSTLVLEMLDAGvEIHCLRDLTRGGLASALNEIATGAGVTLKVQETAIPVAEDVQGACEILGFDPLYVANEGRLVAFIPQNSVSRALEILRSHHQ--QASIIGQVTGTGTgmglVTLESRIGASRILDMLSGEQLPRIC
>UniRef50_B9KGD0(14-336:336) Hydrogenase expression/formation protein HypE n=1 Tax=Campylobacter lari RM2100 RepID=B9KGD0_CAMLR  E=3e-79 s/c=0.92 id=43% cov=96%
MKQITLAHGGGGEEMNALINEIF-SIFENDVLKEANDAAILD---------DLAFSTDSFVLNPIFLKDINIGKLAVCGSVNDVLMVGAKPLYLSLALILEEGFEIEKLKIILNSIKEECDKAGVKLVCGDTKVVPKNKGDEIYINTSCIG--KNIQKINTKNLKSGCSILVSRDIGAHGCAVLVERN--NLEANIQSDCKSLKNEVLALLNAGiSIKAMRDATRGGLSAVLNEWSKLSNLELLIYEEKIPVCDEVLGVCELFGYEPYELANEGTFIICVDKKDEQKALKILK--QFNANAAIIGEITPNEkaRVVLENAYGAKRILETPKGELLPRIC
>UniRef50_P31906(15-346:346) Hydrogenase expression/formation protein hypE n=170 Tax=Bacteria RepID=HYPE_BRAJA  E=7e-78 s/c=0.88 id=51% cov=98%
---VDLSHGSGGRAMAQLISGLFHEAFGNEWLARGNDQSAFDVRA-----GRMVMTTDGYVVSPLFFPGGNIGSLAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFADLKLIAESMGAAAREADVHIITGDTKVVERGKADGLFISTAGVGVVPDGLDLSAEKARVGDRVLISGTLGDHGVAIMSKRQNLAFETEIVSDSASLHDLVARMVQAGgrGIRLMRDPTRGGLAATLNEIAQQSNLGFHLLEEAIPVKPGVAAACELLGLDPLHVANEGKLVAIVAPEAAGAVLAAMRAHPLGRDAADIGEAVADDHhfVQMATSFGGGRIVDWLSGEQLPRIC
>UniRef50_A4CGN3(7-339:339) Hydrogenase expression/formation protein HypE n=2 Tax=Flavobacteriaceae RepID=A4CGN3_9FLAO  E=3e-76 s/c=0.86 id=44% cov=98%
-DIITLGHGSGGLLTNKLLDSGVFHLFDNEHLQQRHDGAMLTL------EGKTAFTTDSFVISPIFFPDSNIGELAVNGTVNDLAMCGAIPQYLSLSFILEEGLKMTEFWEILVSIKSAAEQANIQIVTGDTKVVERGKGDKIFINTTGIGQLHAKADIAPSNVQPGDKIIVSDSIATHGVAIMSVREGLEFESELKSDTRGLSHMVSELLDTFGVdiHLLKDPTRGGVATVLNEIARDRNLGIEILQKDLPLQNEVSALCEILGLDPLYVANEGIFIAVVKDAISEKVVEKLQSMEYGANASIIGDVTENhpKQVVLKSAIGGRRIVNMLAGEQLPRIC
>UniRef50_A7I1Q2(3-390:390) Hydrogenase expression/formation protein HypE n=24 Tax=Epsilonproteobacteria RepID=A7I1Q2_CAMHC  E=4e-76 s/c=0.74 id=44% cov=99%
-KQILLSHGGGGEEMNSLINDTIFKAFDNEILRRANDSAILNFPLDLDKNfdiisanfgdktdyfneksqnfdvsnlngqnktdnmnfnvqnchnkkntqilcGNLAFTTDSFVVTPLFFNGGDIGKIAVCGTVNDLAMVGAKPLFLSCAFIIEEGLEIDTFERILNSMAKTAKEAGVKIVCGDTKVVPRGSGDQIFINTSGIGQILK-AGVQMDCVKKGAKVLISGDIGRHGAVIMAARDEISVSTDLKSDCKPLNAAVtELLKNDVKILALRDATRGGLSAVLNEFAQHLNCEISIRENDIKVAPEVLGICELLGFEPYDLANEGTFVAFIEDGDEIKALEILRK--FNENAAIIGEVTqnEKGRVILQNAYGTERFLEFPKGELLPRIC
>UniRef50_C1SLC8(1-327:327) Hydrogenase expression/formation protein HypE n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SLC8_9BACT  E=7e-72 s/c=0.83 id=43% cov=98%
MEKITMAVGSGGTSSRSFVSEIIFSRLGNEHLLKASDAAIVSTS------GRTAFTTDSYVVRPEFFPGGNIGKIAVCGTINDLLVSGAKPLYLSFGLIMPEGYPVADLERVIDSMAEECRKADVKIVCGDTKVVDKGGCDGLIINTSGIGESLRD-YTEPYNIQEGDAVILTSDVARHGMSVMLARGELGFDGEVLSDCACLKDVFSA-VENLNVKFARDATRGGVAAVLNEIASDSGKGFLMRETDIPMDENVGYLCDMLGFDPLAVANEGLAVIIVSEEDAEKALSNICACENGQRAAIAGRV-EGKNVILETSIGGKRHIEMPAGELLPRIC
>UniRef50_Q8NKU8(4-339:339) Membrane-bound NiFe hydrogenase n=1 Tax=Acidianus ambivalens RepID=Q8NKU8_ACIAM  E=1e-71 s/c=0.81 id=36% cov=99%
-NKIQISHGNGGKETQQLLQRLFFSRLPLELKRVKGGVGIDYPDDGAVLQNNLVVATDSHTVNPYFFPGGDIGYLAVSGTLNDVIMMGAKPIAMLDSIVVSEGFPIDDLEKITGSMIELLKKYNIPLVGGDFKVIEETAmKNSIIINTVGLGVVETGSPI-VDAIKPGDKIIVTGPVGVHGAVIAAMQ--YNISTNLKSDVRPLFELLEVFSKFKGyVHAARDPTRGGLAATLNEWAQLTGNVIVIEEAKVPVLEDVKAITEVTGLDPLNLASEGVGVLAVDSNVEDDVLETLKS--LGFEPASIGYVVEpksEKGIVVaKTAVGGAKILEMPTGDIVPRIC
>UniRef50_A7H7N3(7-340:340) Hydrogenase expression/formation protein HypE n=1 Tax=Anaeromyxobacter sp. Fw109-5 RepID=A7H7N3_ANADF  E=2e-69 s/c=0.79 id=47% cov=99%
--KIGLKHGSGGRAMRQLIEDVFL-TLASPVDGIGL-SALDDGAAIRVGDRWLVVTTDSHVVHPIFFPGGDIGRLSVSGTVNDLAMMGAtEPLGLTCAVVLEDGFPRADLERVVASMRETAREANAPIVTGDTKVMGKDEVDGIVLNTT--GVALAERVVSDAGLRAGDLLIVTGTIGDHGMAIMSRRHDLRLEGDLRSDVAPLNGLVREALRAGGedVVAMKDPTRGGVAGVLHEMAAKGKVGIVIDETALPVRDEVRAAGEMIGIDPLLVANEGKAVIAVRARAADKVLAALRAHPLGASATVIATaIAERPGAVILDTGFGKRMLAEPEGELLPRIC
>UniRef50_A3Z0T5(30-343:343) Hydrogenase expression/formation protein; HypE n=1 Tax=Synechococcus sp. WH 5701 RepID=A3Z0T5_9SYNE  E=1e-59 s/c=0.74 id=46% cov=93%
--------------SQRLLEQVILPALGAT------DGVLLDAASLTTEAGELAFSTDGHVVRPLEFPGGDIGALAVFGTVNDLAMLGATPLALSLGLILEEGLPLSILSRVLSSAAAAAARCGVSVVTGDTKVVERGKADGLFMTTAGIGRIPAGVSIGPSAIRSGDAILVSGDLGRHGLAILAAREELGFSTSLESDLAPLHGSVQALLAAGlELHALRDLTRGGLAAALHELCRDAGLGGLVHEAVVPVHAAVATACELLGLDPLTMASEGRFVMMLPASQAQDALKLLRHEQS--SAAVIGRI-GGEALLLETSLGVRRPLELGRGELLPRIC
>UniRef50_A4XL04(4-324:325) AIR synthase related protein domain protein n=2 Tax=Clostridia RepID=A4XL04_CALS8  E=5e-52 s/c=0.64 id=19% cov=91%
-----------GKIPIEILKEHVFDQKIERSDILLAPGIGEDSAAVDVKSDIAVITMD-----PITAAGSMSGYLSVVVVCNDLAAAGAEPIGVLCTILMPPESSQEEFIQILRDIKEACKRFNIQLLGGHSEVSP--IVTKPLIVSTGFGKVERDMLISTSKAKVGDKIIITKTLGIEGTFILYNEKKEKLKTfltpeevsEIENYINKLSVVEEGLVARKYASSMHDITEGGLFGAIYEVCKASGKGARIYEEKIVLSSSVKKISSFYNLNPYKLISSGSMLITTDKENEL----ICELKEKGIDCYVVGEIIEEPKIEFINSSGEITLIDEL---------
>UniRef50_Q0ABQ2(5-312:321) Thiamine-monophosphate kinase n=3 Tax=Gammaproteobacteria RepID=Q0ABQ2_ALHEH  E=7e-52 s/c=0.67 id=28% cov=86%
----------------QLIRSYFQPdaRGEGVVLGVGDDAALLQPA----PGQLLVTCVDTLVAGVHFpedAPPDAVGHKALAVNLSDLAAMGARPRWFQLALTLPE-IDEAWLAAFSSGLHRLAAEQDVALVGGDTTRGP------LTITVQAMGEVAPAQALRRTGARAGDRLYVTGTLGDAAQGLALWQRgvrsagGDDPAGFLIDRLHRPTPRMAAGRAAAGLARAAIDISDGLLADLGHLLEGGeGLGAVLQADSLPLSPAYRAHCEdsLPGRAALSGGDDYELLFAVAPENEAAFQTALQHVPAG--CTCIGWITEDSAITLQG--------------------
>UniRef50_Q5QVE6(7-316:331) Thiamine monophosphate kinase n=2 Tax=Idiomarina RepID=Q5QVE6_IDILO   E=9e-52 s/c=0.66 id=21% cov=89%
----------------SLINEYFTHRsakRGDVAMGIGDDGAVVR----PMPEHDLVIVTDTLVEGVHFDmttPPRAIGHKSVAVNLSDLAAMGAQPCWISLALTLPR-MDEDWLQEFSGGLDEICSYYDCQLIGGDTTKGP------LTITITAHGQLPSGSAIPRSGAKAGDWIYVSGSLGDAGLGLQVTQNKVSTTGRhlqqVIERLHYPTPRVALGQSLRGVASSCIDISDGLLADLRHLMTEAGTQAQLELEKLPLSLALTETLQVDDalALALTAGDDYELCFTLPEEHRGR-METLTTHLKTRPVC-IGRVANGESGDIQLRYNGE---DWLLAE------
>UniRef50_Q31FT3(6-307:322) Thiamine-monophosphate kinase n=1 Tax=Thiomicrospira crunogena XCL-2 RepID=Q31FT3_THICR  E=3e-50 s/c=0.67 id=21% cov=82%
-------------------------------IGIGDDGAVLSC----LAGNQLVVVTDTLVEGVHFpvkTSAYNIAWKALAVNLSDLAAMGATPAFYSLALSLpPEKNNQAWLELFAGGLKQLASLYNIPLVGGDTTRS-----DRLTITITAQGWVETGNAILRKGAQPDDLIYVSGVLGEGGLGLKAVQQHWD-EASYASAIQKLNqpsPQVTLGYYLKGLATSAIDVSDGLLADLKHILSSSQVSAWVDVDLIPVSDSMRTYLQQSNDwsLPLIAGDDYELCFTVHPDNQASVQDLAKT--LGVSLTKIGQIVAGEGdVQLKNA-------------------
>UniRef50_C9L525(20-342:344) Hydrogenase maturation factor n=1 Tax=Blautia hansenii DSM 20583 RepID=C9L525_RUMHA  E=3e-50 s/c=0.62 id=24% cov=77%
----------------------------------------------------------------------DIGGHSVHITANDLAASGAEPVGIMLTMLLTPDTEEAQLKEIMQDVEKTCKELNMEVLGGHTEVTD--VVKQTLISLTGVGKMKKENVLTTASVKPGDDIVVTKWIGLEGTSIAAKEKESLLLEHFAPPFvetakkfdQYLSVIPEAkIAAEWGVSAMHDITEGGVFGALWEMGSGSGVGLDIDLKEIPIRQETVEVCEVLGLNPYILMSSGSMMIAAKDGYG--LVRKLKQA--GIEAAVVGKATDGNDRILRNG-EDTRYLDKPQSDELYKI-
>UniRef50_O05514(5-309:325) Thiamine-monophosphate kinase n=5 Tax=Bacillus RepID=THIL_BACSU   E=5e-50 s/c=0.66 id=23% cov=54%
----------------------------------------------------------------------DIGYKALAVNISDIAAMGGIPKFYLVSLAVPSKWTESEIKAMYEGMNELAKLYHMDLIGGDTV----STADKLVVTVTVIGEIEKGQACLRSLAKPNDIVFVTGEIGSSAAGLSLLLEETNPQNSSVEtdyfihRHKRPEPRVSVGRLCSIFKrAALNDVSDGLASELNEIAEASCVSIEIVESMLPIHSD----------------------------------------------------------------------------------
>UniRef50_B2SNW6(46-350:365) Thiamine-monophosphate kinase n=21 Tax=Gammaproteobacteria RepID=B2SNW6_XANOP  E=1e-49 s/c=0.65 id=23% cov=82%
-------------------------------LGIGDDAALL----HPPAGEQLAITTDTLNAGVHFpqeTRADDLGWKTLAVNLSDLAAMGAQPRWCTLSLSLPHD-DAAWVDLFADGFFALADAHDIVLVGGDTTRGP------LSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGEAAAALALWQAGqldvtcaaaDPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISDGLLADLGHLCDRSGVGAQLALAALPAMPrsAGTSVAQCPGWQ-LGGGDDYELCFTAAPQHRAAVAQAMEFAE--VAATRIGQIVATPGVVVHDADG-----------------
>UniRef50_A1AS86(15-328:333) Thiamine-monophosphate kinase n=9 Tax=Desulfuromonadales RepID=A1AS86_PELPD  E=3e-49 s/c=0.63 id=23% cov=90%
-----------------LIDRIAAHVAGGEGVitGIGDDAAV----TVLTPGMQLLTSTDMLLEDVHFRTTWHdplaLGRKSLGVSISDVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAGEHGVTLIGGDTC----SSKNGLVISVTIMAEQFPHLILRRSGARAGDEIWVSGTLGDAALVLSLLEDGAvCDEPSLLSRLLDPSPRTRvghALAESGLVSAMIDVSD-GLLADFGHIAQQSGVGGVLYLERLPISADFRRRASRFPSFPhhliLSGGEDYELAFTAAAENHEKIESIVKN--SGIQATAVGIVTSFSGVEVVMEDGS-RYIPRKPG-------
>UniRef50_D2M233(23-319:327) Thiamine-monophosphate kinase n=1 Tax=Bacillus cellulosilyticus DSM 2522 RepID=D2M233_BACS4  E=3e-49 s/c=0.66 id=24% cov=71%
-----------------------------------------------------------------------IGHKALAVNISDIAAMGAIPQYYLVSIAIPKtSWKKKELNDIYNGMNELATVWSMDLIGGDTVSTN----DALVISVTVIGKVEKERRLLRSNARCGDVVFVTGELGLSAYGLQALLEKgyenIDDDELLPYLQAHQKPdphvRAGRLLANCGYRIALNDISDGLASEAKEIADASQVTVELDWAAIPTTNKLKEYPQEKQEEWlLYGGEDFKLVGTIGKENWEKLKAAFQAHSL--PIFKIGSILTGNSEVL----------------------
>UniRef50_B9KXI5(12-331:341) Thiamine-monophosphate kinase n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9KXI5_THERP  E=1e-48 s/c=0.61 id=22% cov=91%
----------GEEELIEQIARLVGDRSNRVSIGIGDDAA----AWRPRAGHELVITTDTLIERVHFrlewTDWEALGHKSLAVNLSDIAAMGAIPRLAVVDLAVRGTERDRDIADFYRGVQALARRFGVAIVGGDTTRSPLG----VAVSITVIGESPRDghRLLRRDAGRPGDLIGVTGPIGLAAAGLRVLERGlktLDGNPVMQEHYHRPQPRVREglLLRRCGVRAAMDISD-GLLGDLQKLCRASGVAAIVDLERVPVPNAIKWAFPDWEEVALRGGDDYELLFAAPPAVFARVARAFARAGL-LPPWKIGQLVEagsaGPIVELRDVTGRCRPAD-----------
>UniRef50_C5BS83(7-296:315) Thiamine-phosphate kinase n=1 Tax=Teredinibacter turnerae T7901 RepID=C5BS83_TERTT  E=2e-48 s/c=0.67 id=29% cov=49%
----------------DLIRDYFARAQDAPGvaLGIGDDCALLE----IPPSEQLAVSVDTLVADVHFPAdaePYLVAERALCVSLSDLAAMGAQPRWITLCLTLP-AFDEAWLAGFSAGLFSRTKAYGCSLVGGDTTRGP------LAISVQVMGTVPVGQALRRKGAQVGDGIYVSGPLGDGAAALALVRGELE-------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4J8J0(14-326:334) Thiamine-monophosphate kinase n=1 Tax=Desulfotomaculum reducens MI-1 RepID=A4J8J0_DESRM  E=2e-48 s/c=0.62 id=23% cov=74%
-----------------------------------------------------------------------VGYKALAVNISDVAAMGGYPSHAVVSVGIPEETRVEDIEELYRGLKEMACRFKVNLVGGDTVKSPG----PLVINIALMGEVEEGRAVFRSGAKPGDLIYTTGFLGTSAAGLYILSHNgdypVELKEKVIRSHLLPEPRVAAARILSELEGvtALDDNSDGLAAELREICRASSAGCLIREKSLPVLPEVEQLACLTGRNtldwIMDGGEDYELLFTLRPERQEYIENALGKE--GILYKAIGIIThSSEGMVLEKEDGAKETI------------
>UniRef50_A6FBC8(7-316:346) Thiamine monophosphate kinase n=1 Tax=Moritella sp. PE36 RepID=A6FBC8_9GAMM  E=3e-48 s/c=0.63 id=24% cov=45%
----------------DLIGQYFTNKsvpRDDVITGIGDDCAILS----VPAGKQLVVTTDTMVSGIHFLsdaNPTDIAHKLVAVNISDIAAMGGQPAWASLALTLP-SFDTEWLSAFSDSLHQQLHRYGVSLIGGDTT------KGNMTLTLTLQGFVEQGKALPRHGAKAGDLIYCSGTIGD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B7V7Q7(5-308:322) Thiamine monophosphate kinase n=11 Tax=Gammaproteobacteria RepID=B7V7Q7_PSEA8  E=5e-48 s/c=0.64 id=25% cov=88%
----------------ELIRRFFAAAACAAPAADVALGIGDDCALLAPPaGEQLAVSTDTLVEGVHFPAGCDpflLAQRALAVSASDLAAMGAAPLAFTLALTLPQA-DAEWLQGFARGLDAMARQCGLALVGGDTTRGP------LSMTLTVFGRVPAGQALTRAGARPGDLLCVGGPLGEAGAALELVLERRSAPAEvaepLLARYWTPAPQFGLGLALRGKASAALDISDGLLADCGHIARASGVALLVECQRLQASAALSGllAGEEALRQQLAAGDDYVLVFTLPPEYLGEIRAAWPAT------AVIGRVEAGQGVHLLDADGKELI-------------
>UniRef50_C3N301(65-393:402) AIR synthase related protein domain protein n=9 Tax=Sulfolobus RepID=C3N301_SULIA  E=2e-47 s/c=0.58 id=23% cov=94%
-----------GKINEDLFNKVIYPHLGEKRTEVLvGPQHGVDTAAIDLQDGRiLVVKTDPVFIVPQF-GFKKAAWFAVHILASDVMTSGIPPQYAVIDVNLPPKIKDDEFEEMWIGIHEALKEIEVMVVGGHTGVYEGT--DYPMVGGfTMFGIGEKEKLGMPSKVRVGDSVIMTKGPAIEATGLLTNLYPEYFKQRLDketfnEAYNIYWKMScwkdGLIASRIGIHLMHDATEGGVFGALTEVARASGKGMNVYEDKLFINSAVREVTRLVNIDPWISISEGTMIIVTDKGK--DVREALIKE--GIEAEIIGEIVDQSGdVKLVKKDGSRVKIEHPLEDPFWR--
>UniRef50_B9ZS01(9-311:324) Thiamine-monophosphate kinase n=1 Tax=Thioalkalivibrio sp. K90mix RepID=B9ZS01_9GAMM  E=4e-47 s/c=0.63 id=25% cov=87%
----------------DLIRRYFAEPAGtspDVRLGIGDDAALL----GVQAGHELVVSVDTMVEGTHYFpdhPPASLGHKALAANLSDLAAMGADPLGAVLSLTLP-SVDHDWLAAFSRGFLALAEQASVPLVGGDTTRGPG------AISVTVLGQVPAGQALRRAGARPGDRLVVSGALGGAAAGLAFEKqrraQGRPPDEESPDCARLFWPsaRLALGRGLRNRARAVIDISDGLLADLGHLAAACGCGARVDWSQLPVDPLLEGQPEEMVRDcVLAGGEDYELLFALPPTEPLELLSLSVRTSL----TVIGEFTSGSDIEVVDAHGAR---------------
>UniRef50_Q0W120(11-306:322) Putative thiamine monophosphate kinase n=2 Tax=Euryarchaeota RepID=Q0W120_UNCMA  E=1e-46 s/c=0.64 id=27% cov=82%
-----------------LIRR-IGKILQSPYL--GDDCAVID-----NGNDYLVVTTDMLHRVTDFpreMTGEDIGWMSVAVSLSDVAGMGARPVGVVAAIGIPGDTDIEFIDGIATGMRNCAKCYGTDIIGGDT-----DQHQELTIVTTAFGRVNKDQVKLRSGAKVGDLLCVTGYLGTTAAGFKVLTGEREASPEdrqiLFRSFFRPEPRLGEGMILAqypGVTAMMDVSD-GLGKSVYELSVASKVGFIVYADALPVREEARKVArsrtELLDMAICFGGE-FELLFTVNPDEVGNI--------KGVDFTVIGKVTE-SGLVLD---------------------
>UniRef50_Q21F21(5-317:334) Thiamine-monophosphate kinase n=1 Tax=Saccharophagus degradans 2-40 RepID=Q21F21_SACD2  E=4e-46 s/c=0.60 id=25% cov=47%
----------------DLIKQYFRnvsPVVEGTTLGNGDDCALLQL----KPNQTMAVSVDTLVEGVHFPCGAsanDIAQRALRTALSDLAAMAATPRWVTLALTLPQH-NSDWLSAFSEGLRADLHAFNCELIGGDTTRG------ALTISVQVMGVVENYPALTRAGAKVGDGIFVTHTLGNGAASLL--------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9XDK5(5-299:310) Thiamine-monophosphate kinase n=1 Tax=bacterium Ellin514 RepID=B9XDK5_9BACT  E=1e-45 s/c=0.63 id=22% cov=85%
----------------ELIGKLTRSLPANKSLvtGAGDDCAVLDLGI---PDRLVLFKTDAVVEGFHFtseTPPEKVGRKALGRCISDIAAMAGTPNSALITLALPRHYDLDYVEGIYAGLGELARKFDVSIAGGETTTNPE----RILISISLLGTVEREKCIFRSGALAGDAIFVTGELGGSISG-----KHLDFEPRLTEAHW--------LRDHFAIHSMIDLSD-GLAGDLRHLLKASHVGSELMASAIPVSREAKLASKAessakpPLLAALTDGEDFELLFTIASKDAVPLLDGWKHQFPKVKLSCIGKVTAGEGINLRDKQGIR---------------
>UniRef50_A4A6E1(3-302:310) Thiamine monophosphate kinase n=2 Tax=unclassified Gammaproteobacteria RepID=A4A6E1_9GAMM  E=6e-45 s/c=0.61 id=23% cov=85%
----------GGKQPRDefsLIARYLKelDRGPAVVVGNGDDGAVLRLDAH----EELVVSVDSMLEGVHFpfdSPPSELAYRAVAAATSDLAAMGARPLGMTLALTIPEA-DDAWLRELRLGLSDAVGDFSLPLVGGDLTRGS------LTLSVQVMGAVPAGGAIRRDGARPGDRVCVSGPLGDAAAGLALIEGRVAGDGpantALREHFWRPMPALDLGISLRGKATAAVDVSDGLLADLGHIAEASKVCVIVDSSQLPISEAVNSIAsgEQALAWALGGGEDYCLGFTLPE-----------SHELPPGSCVIGRVEEGAGVRCDAA-------------------
>UniRef50_Q3ZZF3(10-324:336) Thiamine-monophosphate kinase n=5 Tax=Dehalococcoides RepID=Q3ZZF3_DEHSC  E=1e-44 s/c=0.58 id=20% cov=86%
---------------------------NTPARENLILDIGDDAAVFLPQGYQLV-TVDSLIENVHFnrsmLNWADLGYKALAINMSDIAAMGGLPQYAVVNIDLPPDTLVSSVTDCYNAMYSLANKYQTVIIAGDT-----NQSSIINLAITLLGSAEnPSCLLTRNAAQAGQKIAVTGYLGNAAAGLDMLLNQTEVTDESRrifyRSFYRPKPRIneARLLVKEGVHCCIDISD-GLVTDLGHILRQSRVSARIELDKLPLHPSLRLSYPLQAQNMaLYGGEDYELLFTASAKVIEQI-----SVQSHIPVTIIGEIIPGKPEELKLVDKDGRALQP----------
>UniRef50_A3VRR7(5-304:320) Thiamine-monophosphate kinase n=1 Tax=Parvularcula bermudensis HTCC2503 RepID=A3VRR7_9PROT  E=1e-43 s/c=0.60 id=22% cov=87%
----------------SLIDRYLAPLAIEGAVGLQDDAALF---------EGMIITKDLLVDGVHFRSCDGWGaaaQKALRVNISDLVACGARPAAFALGVVWPKAVTEEEIAAFMEGLSADCARYGLGLIGGDTTRHRADSG-PLTISVTMVGPPAPEGPLRRSGAQVGDVVMVTGTIGEAVLGLKSLLGEIAPTSEGVEAYLRPRPPIDLVDALARYAHAAIDISDGLLADATHIAEASGVVLGLDAAAIPLSPSARAYAEDSGdalLSLLGGGDDYQVIATVPQDNVDPLRAA--AATAQVPLTSIGEVREGaAGTVLRGGDG-----------------
>UniRef50_D2MI54(4-248:278) Thiamine-monophosphate kinase (Fragment) n=1 Tax=Candidatus Poribacteria sp. WGA-A3 RepID=D2MI54_9BACT  E=6e-43 s/c=0.72 id=22% cov=54%
--------------------------------------------------------------------------------LSDVAAMGGTPLYVLVSIAVPVRTPPKNIRALYRGLQDACAPCNVELIGGDTSSSPSH----VFLSLTIVGSVRANRALTRHGAEVGDRLYVTGTVGDANAGLRILQSHSNnlrrfspsaAEKFLIRRHRRPTPRIQvgQLLVDRNLAHAAIDLSDGLSSDVGHVCEESQVGAEIRGEALPLSSPLRAFAKRHDLDP----------------------------------------------------------------------
>UniRef50_A5WHT2(5-306:372) Thiamine-monophosphate kinase n=4 Tax=Gammaproteobacteria RepID=A5WHT2_PSYWF  E=1e-42 s/c=0.58 id=23% cov=66%
----------------ELISRYFTAASSEQALsqsvacttiakGVGDDAAVVALSSPT----QWVTCVDTLVQGRHFAEDWDqvetlafaIGYKSVAVNVSDIAAMGAKPHSIlLALALPQQLAKEAWLSDFAKGLFHACSQFGVQLIGGDTTRSE-----KLVISVTANGFIDKALtPIYRSGAQVGDKVYVSGTLGDACYALYHPDTQVG--KQLSHRLNMPTPRISLgntLAAEGDVTAMIDVSD-GLVQDLSHICEQSDVAVRLHLDKLP--------------------------------------------------------------------------------------
>UniRef50_B5EQ44(2-304:340) Thiamine-monophosphate kinase n=3 Tax=Acidithiobacillus RepID=B5EQ44_ACIF5  E=1e-42 s/c=0.58 id=25% cov=69%
---------AGGEF--AFIEQLrcrLGKMASDVRLGIGDDAAWLD-----PAGRQLVATMDTLVAGRHFFPevsPEDLAWKALAVNLSDLAAMGAEARWCLLSLALPWRAEgyGEWLEAFATGWSALADRHDVTLVGGDTVATDG----PLTLSITALGLSGHG-VMRREAARPGDVIWVTGTLGDAAAALDLALVERGQErravpcsaprrDALEARRLRPTPRLEfgAAALAGGVLCAVDCSDGFLA-DLGHILKASGVHAQVALDALPLSPD----------------------------------------------------------------------------------
>UniRef50_Q04EU4(16-309:328) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Lactobacillales RepID=Q04EU4_OENOB  E=7e-42 s/c=0.59 id=21% cov=70%
-----------------------------------------------------------------------IGQDLVAMVVNDLLAQGAKPLFMLDYIGI-DKVSSDKVAEIVSGIAKACRQSKMALIGGETAELPDMYfKDEYDLAAFAVGVVEEDKILNGNRLQVGDTLLGIASNGLHSNGYSLVRNllltrakktwsqlDDSLQKELLRPTRIYAASLIPLLNNNKIHALSHITGGGLLENVPRML-SNQTAVEINWGSWPIPEIFQRLQEtgkLSNHEMLETFNLGiGMVAAVSADESAEIMNQLKK--SGEKVYQIGKVVSR---------------------------
>UniRef50_A0B852(26-322:325) Thiamine-monophosphate kinase n=1 Tax=Methanosaeta thermophila PT RepID=A0B852_METTP  E=1e-41 s/c=0.58 id=21% cov=64%
--------------------------------------------------------------------------------LSDIAAMGAEPLGVLIASGIPPETDLEFVEEIFEGIRDCVKAHGTEVLGGDT-----DAHRELTICGTALGRVSRERILRRRGARPGDLLCTTGSLGGAGAGLKALKIG---RIDLARRLLEPCPRVREGIALAgtGAVTAMMDNSDGLALSLHDLAEAGGTGFLVECERIPIAEEVRAIAEsdDEALEMvLRAGGDFELLLTVREDMIDDARKAC-------ELTVIGRAVET---------------------------
>UniRef50_D2LH51(7-307:333) Thiamine-monophosphate kinase n=1 Tax=Rhodomicrobium vannielii ATCC 17100 RepID=D2LH51_RHOVA  E=2e-41 s/c=0.57 id=22% cov=71%
---------------NALIAEILAPLATHPGAFGLSDDA---AHLSDLPPNGLVMTTDALVAGVHFFendDPGDAAYKAVAVNVSDLAAKAAKPFAYLLTLALPAAPTEDWARAFAEGLARAQAAFGVSLIGGDTV----TARGPWWLSVTALGDAPA-RPLVRGGGRPGDVLYVTGTLGDAALGLKMRLGLDDFAGALSADetehlarrYLYPEPRVSLRPALAAHASAAMDLSDGLALDLTRLCTASGVTASVDASALPLSEAARsavAAC-----------------------------------------------------------------------------
>UniRef50_C4ZI96(4-331:333) Hydrogenase expression/formation protein n=1 Tax=Eubacterium rectale ATCC 33656 RepID=C4ZI96_EUBR3  E=3e-41 s/c=0.52 id=21% cov=73%
---------------------------------------------------------------------------AVYDALNNIYAMGADPVGIELALLVPTTENEAVLRETVRAIDAVCEKAGIVVLGGHTQVSR--AVKNIVVTVTAIGEAYEQALTPSSAAAPGMDVIVTGYVGLEGTAILANEKRTELETRFSKAFidksAAYIDHISTAMEAasaigAGVAAIHDASQGGIFGALWDMAEASGIGLDIDLKKLPIRQDTIEISEFFDINPYKLLSGGSLIIIAA--DGTRVVRELEKT--GQNAVIVGATTDSNDRVLISG-EERRFLE-----------
>UniRef50_Q2RTC5(9-318:327) Thiamine-monophosphate kinase n=1 Tax=Rhodospirillum rubrum ATCC 11170 RepID=Q2RTC5_RHORT  E=6e-41 s/c=0.55 id=23% cov=87%
-----------------LIGEVFAPLAAScpAALGLGDDAAVLDW----RGRGDLVVSADALVCDVHFLaddPPDTIARKCLRTNLSDMAAMGAKPVGVLLTAALSPALDDAWMEGFARGLGADLADFSVGLLGGDTVSTPGPAQ----FSITILGSMDGHVPLTRSAAQVGDDLWVSGTLGDGALGLRVRQGqilglAEDLRAHLVERYRLPRPRVGLGLALRGLAHGCMDISDGLCADAGHLCAASRVGLVIDAPALPLSEAaatVIADHPALFQAVLGGGDDYELLFTAA--VADRDAVAATTAATGVAVTRIGEVVAGSAVDVRDADG-----------------
>UniRef50_B8J1Z5(30-338:356) Thiamine-monophosphate kinase n=5 Tax=Desulfovibrio RepID=B8J1Z5_DESDA  E=1e-40 s/c=0.55 id=23% cov=54%
--------------------------------------------------------------------------------VSDLAGCGARPLAFTLCLGLPAWVDMDWLNRFFSGMAELAGKHRIALAGGDLSRSTS-----LHISITVWGEaAEPGSFLARGGSMPGDILFLVGPLGLARAGLALLeeqgREALHHWPAVCAAHLRPVPQVDAGLMLSRAgynarpPALMDLSDGilrdlprllGLSGELSATCPEkcTGLGAEIVLPRGRLHPEVLHYAAATGKNP----------------------------------------------------------------------
>UniRef50_D1CEL5(17-352:354) Selenide, water dikinase n=2 Tax=Bacteria RepID=D1CEL5_THET1   E=3e-40 s/c=0.50 id=23% cov=76%
------------------------------------------------EGQALVQTVDFFP--PIVDDPYTFGAIAAANSLSDIYAMGGTPILALNIAGWPGNLPLDMLAQIFRGGMDKVEEAGAVIGGGHT-VMDQEPKYGLCVT----GLIHPGKITTKGAVKPGDLLVLTKPLGTGviTTALKSGKVRDVDIQAAVDSMLRLNKVASELAVELGIRAMTDITGYGLLGHAFEMSEASNVCLNIELSKLPVLPGaldyirqdiypgglnrnrsyltgeqdgrkkisydnsiiVDENLVKLAMDPQTS---GGLLIAVPQEQADEFTA--RAEQRGQSIWIIGFASEGYGVRL----------------------
>UniRef50_A4BAR6(6-307:313) Thiamine monophosphate kinase n=1 Tax=Reinekea blandensis MED297 RepID=A4BAR6_9GAMM  E=5e-40 s/c=0.55 id=19% cov=71%
--------------------------------------------------------------------------------VSDLAAMTATPAFFTLALTLPPATSEDWLTRFALRLRALAETYGIMLAGGDTTAGATLTLTL-SVHGTC------PHPVLRSGARSGDQIWVTGQLGQSAAAlpyILEKREADAPRSWSEAYWNPQPPVLFASQLQGCIHSAIDLSD-GLIGDAAHLARASECDLAIHLDRLPLENDLKQREDEGLKLALAGGDDYQLLFTADPVAEREIVAL--AAQAQVSVTKIGEVQAGKGDIRWYDSGLERQLPW----------
>UniRef50_A6VQ54(23-352:366) Selenide, water dikinase n=13 Tax=Bacteria RepID=A6VQ54_ACTSZ   E=3e-39 s/c=0.50 id=20% cov=75%
-DTIRLtqySHGAguGCKISPKVLGTILqtkLEQFIDPHLLVGNDTADDAAVYDIGNGVGIISTTDFFM--PIVDDPFDFGRIAATNAISDIFAMGGKPIMAIAILGFPiKLLPAEVAQRIVDGGRFACKQAGIALAGGHSIDAP-----EPIFGLAVTGMINTDKVKKNASAQAGCKLYLTKPLGIGVLTTAEKKGKLKAEHQNLATqvMCQMNLVGSAFSEIDGVTAMTDVTGFGLLGHLIELCEGSQLNAVVYMDKIHTLDGVRDYLE----------------------------------------------------------------------------
>UniRef50_B6WXC8(16-332:349) Putative uncharacterized protein n=1 Tax=Desulfovibrio piger ATCC 29098 RepID=B6WXC8_9DELT  E=7e-39 s/c=0.51 id=20% cov=83%
------------------LARHFPATHPSLLLGRGDDCAVLKA------GTPLCVSSDLFLEDVHFrrsyFTPEEIGHKALAVNVSDIAACGGRPLAFTLALGLPDDVDAAWLDRFFSGMAALAQEQRLALAGGDLSRSPF-----LHVSITIWGESyTGGDFLVRGGSMPGDSLFVVGRPGLARVGLQVLekegRAALEHWPAACAAHLLPVPQVDAGLMLARAGAnarppALMDLSDGIMRDLPRLlgrtgesrarregdtgtATDSGLGAAILLPQGMLHPEVVRHARENGLNPvheaLLGGEDYALLGSCAPD----MLPILHAAIPGFMS--IGTITDDGELT-----------------------
>UniRef50_Q10VI8(430-753:767) Selenophosphate synthase n=10 Tax=Cyanobacteria RepID=Q10VI8_TRIEI   E=1e-38 s/c=0.50 id=20% cov=86%
--------GCGAKVTSRVLENVLHKipqEIRRDDILIGMDTPDDAAVIRVPADRVMVQTIDYF--RGLLDDPYLLGKITANHCLSDLFAMGAMAQSGLAIATIPyaaPSKQEDTLYQLLLGATEVLNQSGAVLIGGHTT-----EGEELAFGLTCNGLVSQKKLLYKGGMQPGDMLILTKALGTGtlfAADMRLKARGRWIESAIKSMLGSNQNAAQLLLE-YGVTACTDVTGFGLVGHLLEMLKGQRVGVELDMEAIPVLPGVAETLEQGIFSSLYPGNlqmsasiqnreqasmyplypllfdpqtSGGLLATVPANLASACLNALQQEYF--ETRIIGRV------------------------------
>UniRef50_C9LMP3(20-347:352) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Dialister invisus DSM 15470 RepID=C9LMP3_9FIRM  E=2e-38 s/c=0.49 id=21% cov=72%
-----------------------------------------------------------------------IGQDCVAMSVNDVLVQGARPLFFLDYIA-TGKLDPELMAEIVKGVADACIESGCALLGGETAEMAGFYASGDYdVAGFAVGIVDRKNLITGEKITAGDVILGLPSTGIHSNGYSLVRRiisdnHLNLKETYEGFDKPLgevvltptklyPKLVLPVLKGADVKGLVHITGGGFYDNIPRVLPE-GTRAVLDADKWPLLPIFSFIKAQGGVEPremYRTFNCGlGMLLILSRGEAEKAKKILKN--IGEAVYEVGTISEGNRDVIVT--------------------
>UniRef50_B2A5V9(23-354:360) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF RepID=B2A5V9_NATTJ  E=2e-38 s/c=0.49 id=17% cov=72%
--------------------------------------------------------------------------------VNDVLAQGGQPLIFLDYLAM-DSLEEDLIQDIIQGIVAGCHQSDCSLVGGETAEMPGFYQNGLFdLAGFCVGVVEKDNIVDGSSIKETDQVIGISSSGVHSNGLSLVRKTLikeeggqyeldetpsnletNLGEELLKPTKIYVKPVLSLMEKFSVAGMAHITGGGLPDNLSRIVPD-NLSFSLDLQKlqkmvLPVFSLIQTTGDIPDHDMWRTFNMGiGFTVVLPAEEAQQACEFLR--EQGEKAEIIGTVEQLSQQQGDGVQSGERVM------------
>UniRef50_C1TRR7(33-329:343) Hydrogenase maturation factor n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TRR7_9BACT  E=5e-38 s/c=0.54 id=22% cov=72%
------------------------------------------------------------------------GRLAVHVACNDIAAGGIRPRWAQLLVLVPDKGDEDILKDIMEDAVKAAQEISVTIVGGHSGY--TSALSRPLAAVTAFGSAEPGQMVSTGGASEGDIVCVTRGVGLEGTAILAWDYPEecrskELPEGDIAEARSLADklsVVEEALKLAslGATAMHDPTRGGVLEAMCEMAQGAGMSFRIDGDALPISETVDRFSRAFDFDPMRMISSGALVVTLPGEAVERAGAEL---GSIAPLYPVGVVERGTGVTITSSSG-----------------
>UniRef50_Q46F25(398-695:715) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Methanosarcinaceae RepID=PURL_METBF  E=6e-17 s/c=0.30 id=19% cov=45%
-----------------------------------------------------------------------------------------------------------------------------------------------------IGKVNFETPLPSSfFAKSGDAIILVGeTTADMGGSEYYACFEALNAGKVPSVPKNAPEIIKAVIEAarsGKLSSAHDLSLGGIAAGLARMCRNS--GAKVDLS---------EVSELKAEELLFSEAPARALLATSE--PEAVLEILK----DVPHMVIGKV-EGNSLEVKGK-------------------
>UniRef50_B8DNV5(17-335:350) Phosphoribosylformylglycinamidine cyclo-ligase n=10 Tax=cellular organisms RepID=PUR5_DESVM  E=8e-38 s/c=0.50 id=20% cov=28%
----------------------------------------------------------------------------VAMSVNDILVQGARPLFFLDYFA-TGKLDVDVAASVISGVAEGCRRASCALLGGETAEMPEMYAPGEYdLAGFCVGLVDNTRIVDGSSIRVGDSII---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1E7V6(423-748:804) Selenide, water dikinase n=4 Tax=cellular organisms RepID=C1E7V6_9CHLO  E=8e-38 s/c=0.49 id=21% cov=73%
-----------------------------------------------------VHTVDffrSFVDDPYIF-----GQIAVVHALGDCWAMGAEPHAVLAIAQVPYGLEsqvEDELWQMMSGATAVLEEVGCALAGGHSC-----EGAELALGFSVHGVAKREKLMKKGGMKPGQVLIVTKPIGTGTLFAADMRAKAEgrWVTKALDSMRKPSAVAAQLLVEHGAKACTDVTGFGLLGHLVEMCKGANLAAVLDLDEIPVLDGAEECLKMGITSSLQPANvrlsravanqdgiannprypliydpqtAGGMLAAVPKENAEACIEALRQAGYPSTCG-IGEIIE----------------------------
>UniRef50_A8G794(11-338:347) Phosphoribosylformylglycinamidine cyclo-ligase n=10 Tax=Prochlorococcus marinus RepID=PUR5_PROM2  E=3e-37 s/c=0.48 id=17% cov=29%
--------------------------------------------------------------------------------INDIITSGAKPLFFLDYIA-TGKLDKKQLLRVVQGISHGCGENNCSLLGGETAEMPGfYSKNKYDLAGFCVGIVDEDKLINGKKVSENDLIIALKSNGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P22102(468-787:1010) Phosphoribosylglycinamide formyltransferase n=303 Tax=cellular organisms RepID=PUR2_HUMAN  E=4e-37 s/c=0.49 id=22% cov=71%
--------------------------------------------------------------------------------VNDILAQGAEPLFFLDYFSC-GKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYdLAGFAVGAMERDQKLPHlERITEGDVVVGIASSGLHSNGFSLVRKivaksslqysspapdgcgDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPE-KLGVDLDAQTWRIPRVFSWLQQEGHLseeEMARTFNCGvGAVLVVSKEQTEQILRDIQQHK--EEAWVIGSVVARaegsPRVKVKNLIESMQI-------------
>UniRef50_B3V648(18-345:348) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=uncultured marine crenarchaeote KM3-153-F8 RepID=B3V648_9ARCH  E=7e-37 s/c=0.48 id=18% cov=90%
------------KSSHSEISKLLGSTlsLRNGRIGEVIAGSGHYAGVIKlRNDDYLALHTDGVGTKVLIAQQYskfdTVGIDCIAMNVNDLICVGAEPISLVDYIALKKNNPV-LVKEITKGLVKGAKLSNTPIIGGETAIMPdvieGYGNKAFDLAASAVGVINKKTNMLNRKIKSGDIIIGLQSSGIHSNGATLARKVLLEKYSLRKKMYKSKRLGDLLLEptiiyskaimtilnnIKSIHGLAHITGGAFTK-LPRI-GSGRVGFSLDLPKPPfIFELIQETGNISDKEMQRTFNMGyGFVIICPKSQYVNVDSILSEYK--INNTILGNIVSHRGVKVNGK-------------------
>UniRef50_Q67KF8(415-765:778) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Bacteria RepID=PURL_SYMTH  E=2e-18 s/c=0.27 id=20% cov=73%
--------------------------------------------------------------------------IAVAEAARNCVVTGARPVAITNNCNFGNPEKPEIFWTFdeaITGMAEACEALGTPVTGGNVSFYNETSGEAIHPTPT-IGMIavheNLDRLTTPGFKQVGDVILLLGETrdelgGSEYARLIHGVLAGDAPALDLAFEKRLQDVVLRAIHEGLVTAAHDVAEGGLAVALAEMAiaaaePSLGCQVSIFLGEGRVDGQ------------LFGESQSRILVTATREQVGRLQALLMVEQ--IPFRVLGDVTADGRFRLaalapgsgsAHVYRRQELIDLPVADLV----
>UniRef50_Q30VD3(14-326:339) Thiamine-monophosphate kinase n=1 Tax=Desulfovibrio desulfuricans subsp. desulfuricans str. G20 RepID=Q30VD3_DESDG  E=1e-36 s/c=0.50 id=24% cov=85%
------------------IDRHFCNEHPHMLRGRGDDCCELACP------PRMTLSTDLFMQDTHFrlsyFSAADIGHKALAVNISDIAAAGARPLGFSMGLMVPEKqpgphrLTGAFWDSLFDGMAQLARSHGMALTGGDLT---RAGTFGLCVTVWG-GPCGDAPFLRRTGCRPGDAVFLAGEAGLARTGLMALEamgaEAAGEYPHAVAAHLRPVPLVRSGQRLAALQGARPQSRitlmdlsDGLARDLPRLfaAGEGTCGASLVLPDASLHPDVRRWAAEQGTDaavhAFCGGEDYALLGTCAPEAVADVIEA--AACDGVPVRVLGTVHGEPVVMLNG--------------------
>UniRef50_C1SM36(24-343:345) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SM36_9BACT  E=1e-36 s/c=0.49 id=22% cov=68%
--------------------------------------------------------------------------------VNDIIVTGAKPLFFLDYMA-TGKLSSEKMAQVVEGIAEGCRQAGSPLVGGETAEMPGmYSGEDFDLAGFAVGILDKPKAVTGERISKGDVLVGLPSSGLHSNGYSLARKLFFEKlsmkpddilyddvmlkhALLEPTRIYVQQVLSVIEKGIDVKGMVHITGGGFYDNIPRILPE-GAGVKINPDAFPTPGIYKFILEKSGIeekELYRVFNMGiGYIMVLEHSEAEKCMSLID------DACVIGNVTDTGIVEIEG--------------------
>UniRef50_UPI0001C41B3D(408-723:736) phosphoribosylformylglycinamidine (FGAM) synthase II PurL n=1 Tax=Methanobrevibacter ruminantium M1 RepID=UPI0001C41B3D  E=7e-31 s/c=0.43 id=18% cov=84%
--------------------------------KPGDDAAVLQ----IDDETAVALTADSNTVHTK-LSPYDGGAGSVAEAIRNVVSMGAKPYAIVDCLNFGNPETPEILWQFkecIRGMSDIAEKFEAPVISGNVSFYNETEGIKInpTPAVGVIGVEKLSSIRTLPFKNEGDKIIIIGKTYDELGGseyhraVHNLEQGEAPKIRIDDELAAANAVLDLIENDGDyvkflegedklnIKATHDVSAGGIAIALSEMVMKGKLGCEIDISNVPAEE------NISDNDLLFSESHGRYIIAVDADKAEEIV-----NSIDIDAAIIGEV-KGDSLIIKNND--ETIVDFAIDEL-----
>UniRef50_C7MMK4(39-385:411) Phosphoribosylformylglycinamidine cyclo-ligase n=7 Tax=Coriobacteriaceae RepID=C7MMK4_CRYCD  E=2e-36 s/c=0.45 id=23% cov=68%
--------------------------------------------------------------------------------VNDILATGAEPLFFLDYIAV-GKLKSEAVAEIVGGIAEGCRQAGCALIGGEMAEHPGvMDPEEYDLSGFSVGVVDRARMLDPENVTEGDVLLGLASSGLHSNGYSLARKvclegrthyevrlpqsllgGESVQDALLEPTRIYVKSVHTALTNhpHAVHALAHITGGGITENLNR-ALPSHLDAQVDIGSWtmkPIIPFVCRAAKLSESEALKTFNMGlGLVLIVDAAAVDSVEHTLQ--EAGEEVFRVGHVVAGSG-------------------------
>UniRef50_Q46I38(12-318:327) Thiamine-phosphate kinase n=4 Tax=Prochlorococcus marinus RepID=Q46I38_PROMT  E=2e-36 s/c=0.50 id=18% cov=68%
----------------------------------------------------------------------DIGWKCITTNISDLICSGSENItSFTVGLVLPPNTHWKWVENLYEGMLEAMQEFGGEIIGGDCSSGETK-----MISITAIGEMNLPR-LHRGNALPGDYIVSTGFHGLSRLGLALLtsqklpseaQLSPELINRAINAHKRPYPALEALKALIACKpesiswrAAGTDSSDGLIESIRGICQASNCQAV--LSKTSILKDTDWPKDDIWDEWlLNGGEDYELILSLPKEWAKSLSNKLKS------AKIIGFIKEGK--------------------------
>UniRef50_Q83H66(95-391:760) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Actinomycetales RepID=PURL_TROW8  E=2e-36 s/c=0.52 id=19% cov=68%
------------------------------------------------------------------------------GIVRDIIAMGAKPVALMDSLRFGAASDPDtqrVADGVVSGISFYGNCLGVPNIGGETAFDPVYQGNPL-VNVLCVGVMRRENIRLANASGPGNLVVLfgapTGRDGIGGASVLASDSFTSDAKANRPAVQIGDPFVEKLLtecclelyAADLVVAIQDLGAAGISCAASELAHNGRVGIRLDLSAVPLRDTTLAPDEI-----LVSESQERMMAIVHPDNLEAFFEI--TNRWGISGAVIGEVDNSQYLTV----------------------
>UniRef50_A4VKS6(15-335:344) Selenide, water dikinase n=2 Tax=Bacteria RepID=A4VKS6_PSEU5   E=3e-36 s/c=0.48 id=22% cov=62%
-------------------------------------ASRDDAAVYGIDEERgVVSTTDFFM--PIVDDPFDFGRIAATNAISDIYAMGGDPLMAIAILGWPVNvLPPEVAREVIAGGRAVCDAAGIPLAGGHSIDAP-----EPIFGLAVSGLVNKRQIKRNDTATAGCKLYLTKPLGIGILTTAEKKAKLRVEdvGLARDWMCTLNTAGSRFGKLEGVRAMTDVTGFGLLGHLVEMADGSGLTAEIEYARVP--------------------------------------------------------------------------------------
>UniRef50_Q1IVJ6(5-319:320) Selenophosphate synthase n=1 Tax=Candidatus Koribacter versatilis Ellin345 RepID=Q1IVJ6_ACIBL  E=5e-36 s/c=0.49 id=22% cov=68%
-----------------------------------------------------------------------FGQIAATNALSDVYAMGGKPVSALAMVCFPDKGDPEVLERILAGGLSKMIEANCTVIGGHSIRDE-----EIKFGYAVTGTIHPQKVLKNAGAVAGDALLFTKSLGTGVISTAIKRGKAEPEwiAAAERSMTTLNKLAAEVIAAGdyAVHGMTDITGFGMIGHGREMALGSGVTLRIRAADVPVLPGALE-CVRLGFVPGGLNNnrdfaeclvtyaddvphelrtilydpqtAGGLLISVSEADAKRLLRAMQNA--GVPAVRIGEVI-----------------------------
>UniRef50_Q2NE22(9-313:333) ThiL n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NE22_METST   E=1e-35 s/c=0.50 id=19% cov=67%
---------------RKLIQRLLKKR--DETLGNIDNTILksyhDDAAIEENTSKYTVLSTDMLIQHSHFpkqMTYFQMGEKIVTVNVSDILAMNATPVSILIAMALPSTLTIDEFDEIIDGILYKCKEYGVTLIGGDL-----NQSDEIILSATTTGKINKNIKLQ-SNIQEDNLVAITGQLGMPAAALDLLSKYEikdlsnEYEEIIKSILEPNLPIktAKFLREHPtLITSMTDITDGLAieLGHLHE--KNTNIGFEIYADKLP--------------------------------------------------------------------------------------
>UniRef50_Q18JI5(417-642:725) Phosphoribosylformylglycinamidine synthase 2 n=8 Tax=Halobacteriaceae RepID=PURL_HALWD  E=3e-11 s/c=0.32 id=18% cov=38%
------------------------------------------------------------------------------------------------------------FKDIVQGLADMCHTLSIPVVGGNVSLYNDSTSGPIppTPTLALVGTKKTFDAPPAALTGDGTLLLVgHQSNNLGGSELLAQIGGTDKFPALPSNPTAVVDSLARVANHPSTLATHDVSTGGLAVTLAEL------------------------------------------------------------------------------------------------------
>UniRef50_Q8NQV0(41-318:331) Thiamine monophosphate kinase n=5 Tax=Corynebacterium RepID=Q8NQV0_CORGL  E=3e-35 s/c=0.54 id=17% cov=54%
----------------------------------------------------------------------------------DIEAMGARPVAALLAISAPTHTPVEFVRGLARGMNQRLEEYSAELVGGDIT-----SGDSLVIAVTAIGQLGGSLPeLTLGRARPGQTLVAHGKIGYSAAGLALLQHfgpdnvPEHLRPLVDAHCAPVLTPGRGMVARAAGATAMTDNSDGLIVDLNQMAMKSGVRIDVDSSSISPDELLSEAASVLGTDAW---------------------------------------------------------------------
>UniRef50_D1YVN6(19-314:328) Putative thiamine-monophosphate kinase n=1 Tax=Methanocella paludicola SANAE RepID=D1YVN6_METPS  E=5e-35 s/c=0.51 id=19% cov=67%
------------------------------------------------------------------------GYCSVLVNVHDIAAMGGRPLGMVDVFS---SNSDEITQRVLKGMKAGIDKFGVPIVGGHVHPDTPYAA----LDVAILGIAKKDTVIYSSTAKPGDDVVLAIDMDgrVHPSCDLNWDTTFLKDASIVR--QQVGSMVE-LAERKMLTAGKDVSNPGIIGTLGMLLEVSGVGADVDMSAMPKPESLEW------EHWLKMYPGMGFIVTCKPENTEQVLDIYRNHKL--NATKVGKIVSAPRLDL----------------------
>UniRef50_A2BKY5(10-318:326) Predicted thiamine-monophosphate kinase n=1 Tax=Hyperthermus butylicus DSM 5456 RepID=A2BKY5_HYPBU  E=5e-35 s/c=0.49 id=24% cov=88%
------------EAVKRLIEEILAGQWRCPSLGPGDDAACVGGGF-----QNLILKIDGGSLASLWAPwmePADIGWQAVAAAASDLVAKGAKPLAFAVSLGLDPGEDIETLKGIVRGAAEAAQAHGAWLLGGDTNSCSNCG----WIDVAAVGLAEKPVGLQAS---PGDTVYVtTGRIGLAGLVLDSlakgrWREAMEAYPRAFSEFARPRARLEFVELAGtGCITAATDSSDGLAYSLGKIAEAAH--ALVELENIPVEPEALRYAEEYGVDPlelaLYGGQEYEVIFAVRGGCEKLVEE--RAATLGLAVARIGRLREGPqGITYRGRTLSVR--------------
>UniRef50_Q11IV2(61-370:744) Phosphoribosylformylglycinamidine synthase 2 n=111 Tax=Bacteria RepID=PURL_MESSB  E=5e-35 s/c=0.48 id=20% cov=34%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELMATGAVIAIQDMGAAGLTCSAVEMGAKGDLGIELDLDKVPVREE-----RMSAYEMMLSESQERMLMVLRPEKEPEAEEIFRK--WGLDFAIVGRTTDD--LRFRILHGGEEVANLPIKEL-----
>UniRef50_A8FAM7(437-716:743) Phosphoribosylformylglycinamidine synthase 2 n=93 Tax=Firmicutes RepID=PURL_BACP2  E=4e-30 s/c=0.48 id=19% cov=68%
------------------------------------------------------------------------GKIAVAEAARNIVCSGARPLAVTDNLNFGNPEKPEIFWQIeksADGISEACRTLSTPVIGGNVSLYNESNGTAIYPTpvIGMVGLVEDTAHItTKSFQQAGDVIFVIGETKEEFAGSELQKmtegriYGKAPEIDLDVELARQEALLAAIQN-GLVQSAHDVSEGGLGVALAESTFGTdGLGADIQID-------------LDSEASLFSETQSRFVVTVKPEHREAFAAAVK------DAKEVGTVTNDGVFTVKNQEG-----------------
>UniRef50_B4X4C8(390-717:738) Selenide, water dikinase, putative n=2 Tax=Alcanivorax RepID=B4X4C8_9GAMM  E=3e-34 s/c=0.45 id=22% cov=80%
----------------------------NPGIEAGVDAADDAAIIDWPAGQRLVQSLDFFPA--FIDEPYLFGRIAALHSLSDLYAMNARPHSALANITLPwhhPRLQGRDLQRMMAGAVRELNAAGCTLVGGHTIEGPQMAA-----GFTVNGQADPAQLWHKRGARDGDRLILTKPLGSGVQLAALMQanssngaafHGPWLDTTLR-HLLTSNHMAQRALQDVPVNACTDITGFGLLGHLYEISQQSGVTLSVDCHKVPLLPGTLSLiqqgvastlsdanrqilvhcqQPQPVDDALLTAlcdpqTAGGLVFCLPADYAGQALQHLDRE--GIAATDIGKV------------------------------
>UniRef50_A8UTM0(21-333:335) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8UTM0_9AQUI  E=3e-34 s/c=0.47 id=21% cov=68%
--------------------------------------------------------------------------------VNDVITTGADPLLFLDYIA-TGRIDLQVLKAVIDGVVEGCKRGEVLLAGGETAEMPGFYPEGVYdLAGFCVGVCERGEVITGEGVRSGDVLLGLRSSGFHSNGFSLIRKvlkdkgvkltdrveelGQSVGEVLLTPTRIYTPEVKLLKSNVELKALAHITGGGIPENLIRVLPE-GIRAVVDKKSIPENPVFAWIQKLGGVeerEMFRTFNMGvGMIAVVSPEDCDKALDAL-----GRDAFVCGHLEEGKREVV----------------------
>UniRef50_A5VHT8(425-718:742) Phosphoribosylformylglycinamidine synthase 2 n=50 Tax=Bacteria RepID=PURL_LACRD  E=4e-34 s/c=0.50 id=20% cov=80%
----------------------------NTVAGPGSDAGVLR---IRGTHKGLAMTTDGNGRFVYLSPEVG-GQIALVEAAANIIASGAEPLAITDCLNYGDPTDPEIFWELhqsVQGMADACREFNTPVISGNVSLYNENNGQAIHPTpmVGMVGLIKNiDRVIPSFVQHPGDKVYLVGQTRDDYAGSELQKMMTGDISGIVEsfDLHHVHQYMQRLlttMENGLVSSAHDLSEGGLGVALAETVFKTDLGLKIDLADQHTAR-------------LFSETPGRFIVTVAPEKATEFEQVL-----GKDAHLIGEVTNSHWLMVKLANG-----------------
>UniRef50_A5VHT8(64-375:742) Phosphoribosylformylglycinamidine synthase 2 n=50 Tax=Bacteria RepID=PURL_LACRD  E=1e-32 s/c=0.46 id=20% cov=23%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMASEGQSGMELNLDLVPQREPGMSAYEI-----MLSESQERMLLCVKKGHEEDVKKIFDFYDL--EAVTIGRITAGHDYVL----------------------
>UniRef50_C3PG01(37-321:332) Thiamin-monophosphate kinase n=15 Tax=Corynebacterium RepID=C3PG01_CORA7  E=4e-34 s/c=0.52 id=22% cov=65%
----------------------------------------------------------------------------------DIEAMGARPTAALLAIAAPGDTPVDFVRGIAQGIAERCAVYNAELVGGDLTRSES-----LIINVTALGSLGGsGAALTLDGARAGQKLVAHGKIGYSGAGLALLqRYGRALPPELEefwplvdAHCAPSLTPGRGVIARATGSTSMTDNSDGLVRDVGHLAQRSGVHIDLDRGAIAPDPLLAAAGALLDIDPWewvlTGGEDHTLLATT-----------YKSAPSGF--REIGRVMRGTGVTIDGE-------------------
>UniRef50_P60819(6-343:349) Selenide, water dikinase n=13 Tax=Methanococcales RepID=SELD_METJA   E=5e-34 s/c=0.43 id=19% cov=78%
-------------------------------------GLGDDASIIKRNGLVIAKTVDVFT--PIVDDPYIQGKIAACNSTSDIYAMGlLDIVGVLAIVGIPEKLPIHVVREMLKGFQDFCRENKTTIVGGHTILNP-----WPLIGGAVTGVGREEEVLTKAGVKVGDVLILTKPLGTQTAMALSripEEFKDLISITEEERDYIINKAIEIMTTSNRYAlkalrkaeervgdkianALTDITGFGILGHSNEMAKNSNVLIEINLLPCIKRtPELSRLFGHALLDGYGAETAGGLLISAKEEYKDNLIDELEKAKC--YAFEVGRVV-----------------------------
>UniRef50_A2SPR4(41-327:331) Phosphoribosylformylglycinamidine cyclo-ligase n=4 Tax=Methanomicrobiales RepID=A2SPR4_METLZ  E=5e-34 s/c=0.51 id=21% cov=67%
--------------------------------------------------------------------------------VNDMYVMNIEPIAFVDYIA-TEGINTEQMIQIGVGLNEGARLSNLNIVGGETATL-KGMINGLDLAGTCLGVQDKDKVVTGEKVAPGDIIIGVASTGVHSNGYTLARKVAEENGGYATVLLSGRTVGEALLvptriysevldvcSKAVVHGMCHVTGGGLLNFL----RISSYGFAI-EDPLEVPEILAWIAEKGNLEMnelYRTFNMGmGFAFIVPKESVETVLSMVEGSK------VVGRVIEEHKVTLKG--------------------
>UniRef50_C3N674(391-675:709) Phosphoribosylformylglycinamidine synthase 2 n=12 Tax=Sulfolobaceae RepID=PURL_SULIA  E=1e-10 s/c=0.25 id=21% cov=54%
----------------------------------------------------------------------------------------------------------------IRGIGEATRFFNIPIVGGKVSFYNENSQGKPIKPTpliVMAGLV-QGKLLKNRVEDSSYVVLLGYTRKELGGSLLSKIFKVPSQApkvRLQEDLLSSEVVIDAINE-EKITFAKDISRGGLAASLFNIIVH-GYGVEI--STKSILSDTDNVVEN-----LFSESSGRFVILTNE--PEWIVE--KSRSKGIVASIIGKV------------------------------
>UniRef50_Q1NV35(5-238:322) Selenide water dikinase n=2 Tax=delta proteobacterium MLMS-1 RepID=Q1NV35_9DELT  E=1e-33 s/c=0.62 id=20% cov=55%
-----------------------------------------------------------------------FGRIAAANALSDVYAMGGKPLLAMNLVAFPiKRLDCKILKEILRGGLDALNEAGTLLVGGHSIEDE-----EIKYGLSLTGTVHPNRLLLNSGAQPGDQLLLTKPIGTGilATAIKGGLADGRIEEMIGQVMVTLNREAARIMITSGANACTDITGFGLLGHLHEMAAASSVAIGVDCRQVPLLPQVMHFAEM---------------------------------------------------------------------------
>UniRef50_C0WNA5(16-336:338) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Lactobacillus RepID=C0WNA5_LACBU  E=2e-33 s/c=0.45 id=20% cov=87%
----------------KLVDE-IKQLSHNDALGAF--GGMFPLSLGHYQNPVLVSGTDGVGTKLLIAIKAgihdTIGVDLVAMCVNDVLAQGAKPLFFLDYLG-TGHLNQSEAKAILTGVVDGVSQADAKLVGGETAEMPDMYQHGHYdLAGFTVGIADQDKLLKSDNLREGDVLLGLASNGLHSNGFSLVRDilfkqnhysldetlpgcQLDLKHELLRPTRIYVKSVLPLIEQGLIQSIAHITGGGLIENVGRILPD-HLDAAFNLNSWQVPAIMTNLQKIDHLsfnDMKQTFNLGlGMVLAIHPTDVDRVKAELEKA--GETVYQVGKLVSGSKKVV----------------------
>UniRef50_B8DQ45(14-352:365) Thiamine-monophosphate kinase n=1 Tax=Desulfovibrio vulgaris str. 'Miyazaki F' RepID=B8DQ45_DESVM  E=2e-33 s/c=0.43 id=29% cov=32%
------------------IDRHFTNAHPHLCVGRGDDCAVIACP------PRMAVSTDLFNEHSHFrtsyFTPGDIGHKALAVNISDLAACGARPLGFSLALTAPADLSREFCDEMLGAMAALAREHDMALSGGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1ZMQ5(409-719:755) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Microscilla marina ATCC 23134 RepID=A1ZMQ5_9SPHI  E=4e-21 s/c=0.33 id=16% cov=52%
-----------------------------------------------------------------------IGAmIAVCESARNVVCAGGNPVAITNNLNFGNPYNQEVYWQFvqsVKGIIDACEKLETPVTGGNVSFYNQASTVSkeggnvtnavlPTPTIGMLGLMDNlEHRMTLDFKNVGDIIYVIGEPknDIAGSEYLTSYHNFKESSAPHFDLEAEYDLqqtVKALIRDKQIQSAHDISDGGLFVTLAESAMPRDLGFSI--------------------------------------------------------------------------------------------
>UniRef50_C1SM10(8-284:297) Thiamine-monophosphate kinase n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SM10_9BACT  E=3e-33 s/c=0.52 id=23% cov=81%
----------------SLIERLsSMLNNGGVTLGVGDDAALF---------GETLVAKDIMVEGVHFTKGApflHIMRKIVTANVSDIAAMGGTAEYGLLGIAIPEGYDVN-----AEDIVKPFEMYGVKLIGGDTT----SSQDSLFVSVTIIGR-KNQHVLQRSGANAGDVIYLSRPVGR--VRELLEQELAGGDTYNHYLIKAETELGDLLGRTGLATSCIDVSD-GVGRDASHIADKSGVCMVIEESRFPVeHLHVKGDAVMF---ALGSGEEFALLFTVAEKDISEL------EMLAPSAVRVGYVETGSGVYLEREQG-----------------
>UniRef50_B8HPV7(54-363:367) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Cyanothece sp. PCC 7425 RepID=PUR5_CYAP4  E=5e-33 s/c=0.46 id=22% cov=69%
--------------------------------------------------------------------------------VNDVLTCGAEPLFFLDYLA-TGHLEPEALTDVIAGIAQGCQQAGCALLGGETAEMPGfYPVGEYDLAGFCVGIVEKAEMLNGSQVRMGDRAIGLASSGVHSNGYSLVRKivdefigpaareqsEAGATEALVSPWsitpwaeredlppvdrqqslgaalltptqIYVKPVLAAQRSGLTLHGMAHITGGGLPENLPRCLGE-GQSVQLDPQSWPAPPIFDWIASTGSVptaAMFDTFNMGiGFVLIVPPDEVESALRWFNTQQC--PAYGIGEVVAGAGEVL----------------------
>UniRef50_A4S9M0(427-753:796) Predicted protein n=4 Tax=root RepID=A4S9M0_OSTLU   E=7e-33 s/c=0.44 id=22% cov=80%
----------------------------NPNVEVGIDQPDDAAVVSVPDGMVGVQTVDyfrAFVDDPYIF-----GQIAAVHALGDCWAMGADPHAALAIATVPYGLEsqvEETLYQMMAGACDILRDAGCGLAGGHSS-----EGAELSLGFSVHGAAPREKLMKKGGMRAGHKIIITKPIGTGTLFAADMRSKAqgRWVSNALDSMRQPSAVAARTLFEHGATACTDVTGFGVLGHLVEMCKGSSAACVLDMDALPVLPGALECVEIGITSSLQPANvrlaraianpaavsgaarypllfdpqtAGGMLASLPSASADAAVEALKRAGY-EHTTIIGEVLE----------------------------
>UniRef50_O67139(6-335:336) Selenide, water dikinase n=2 Tax=Aquificaceae RepID=SELD_AQUAE   E=1e-32 s/c=0.43 id=18% cov=51%
------------------------------------------------------------------------GAISTANALSDVYAMGGIPVnALAISCFNNCELDIEIFREVIRGALDKLREAKTVLLGGHT-IDDKEPKFGLSVA----GICPEGKYITQSGAQVGQLLILTKPIG-TGILIKGLKEGILKEEDIneaIENMLALNDKARNLMLSLDATACTDVTGFGLLGHAWNICKNSNIGARIFFEKVP--------------------------------------------------------------------------------------
>UniRef50_A7I192(4-260:277) Thiamine-monophosphate kinase (Thiamine-phosphatekinase) n=18 Tax=Campylobacter RepID=A7I192_CAMHC  E=1e-32 s/c=0.56 id=20% cov=42%
-------------------ERYIFEKFSDK--KNGDDGALV---------GKWVFSKDLFVQNIHFKRSWlslrQIAVKSMLVNISDAVAMNARPKYALLGLELPKEIGISEIDELCGGFLDICKKFNIKIIGGDTI-----SGDRISISVTII--SKTKKAVFRKGAKIGDFIAFTGNLG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1JHF1(36-345:362) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=environmental samples RepID=D1JHF1_9ARCH  E=2e-32 s/c=0.46 id=19% cov=68%
--------------------------------------------------------------------------------VNDILCVGAEPISLVDYIALCEP-DPELLEEIGKGLLKGAEIANITISGGEIAIVKDMVKGvrknrEFDLVGTAVGTVSLDKVIVGANIQEKDVIIGLSSSGIHSNGLSLARHIFLKTGAidehfdvlektigaelLEPTHIYVPEIMEMINSNLDIKALMHITGDGFL-NLTRVKSEVGFVIEYLPETPPIFTLLQKRGNVTDEEMFRVYNMGiGFCVILPEQEAEVAIEIASRHK--VDAFRLGYVVKDP--------------------------
>UniRef50_A6QAK6(449-716:740) Phosphoribosylformylglycinamidine synthase 2 n=33 Tax=Epsilonproteobacteria RepID=PURL_SULNB  E=2e-20 s/c=0.38 id=18% cov=62%
-----------------------------------------------------------------------------------VAMSGARPLSITDCLNYGNPENPEVMWQFAQgceGIKEACLELNTPVVSGNVSLYNETNGVSVFPTpaIAMVGLNDDQNKVLPSVFQhEGNNIVLIGETKGEFGGSLYIKELFGetvgtLPSFDYKTELKLWELVIEANKIGLLESAKDVNVGGIAIALSKMAAVSSKGITVKASVSNSRDIFDE-------------SQSRALLEVADADLEELLDM--AAGLGLKAEVIGKI------------------------------
>UniRef50_A7I447(95-375:378) Selenide, water dikinase n=3 Tax=Campylobacter RepID=A7I447_CAMHC   E=7e-32 s/c=0.50 id=22% cov=69%
------------------------------------------------------------------------GQIAAANSISDIFAMGAKPINALNIVGFDEcNFGGEILSEILAGGKSKIKEAGAVLVGGHTIRSAET-----FYGLSVTGLVKGRDFWANNTAVAGDVLILTKPIGTGIITTAIKSKMIDFKdfEDAIESMISLNFKACEILRNYEIHACTDVTGFGFLGHLSEMLNK-NISFEVSSQNFHYFKSVKKCLEMGlipggsyknseftskfcdkkpPIELCDAQTSGGLLAAVSENEVAKVLNHLQNE--GIDAFLVGFAVPKK--------------------------
>UniRef50_C0VG64(47-305:349) AIR synthase-like protein n=3 Tax=Gammaproteobacteria RepID=C0VG64_9GAMM  E=1e-31 s/c=0.54 id=20% cov=27%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYAARDISNAGILGSLLMLLEATQSGADIDLQKIPKPQNVDWQT------WLQIFPSYGFLLTADEGECEEIIELFDSQ--GICCAVIGESNASGKVYV----------------------
>UniRef50_Q3ARU4(447-740:761) Phosphoribosylformylglycinamidine synthase 2 n=18 Tax=Bacteria RepID=PURL_CHLCH  E=6e-29 s/c=0.44 id=19% cov=73%
------------------------------------------------------------------------GKIAVAECARNIACTGARPLAITNCLNFGNPLKPEVyfqFKESVRGMGEACRTFNTPVTGGNVSFYNETFIAGqrtaiyPTPMIGMIGLLDNIENLVGSTFTAsGDRILLLGNPqltldGSEYLVMQYGTPGQDAPAVDLEHEAQLQRLLVALAEQKLLHSAHDVSDGGLLVALAEKAMMNQempLSFRVHLSNNDKSETAIQQQ-------LFSEAQGRVVLSAAPEAVAAIMAL--ANDYNLPIQDIGEVV--NQQTISLSINEQEVVNLP---------
>UniRef50_O67691(52-362:745) Phosphoribosylformylglycinamidine synthase 2 n=6 Tax=Aquificales RepID=PURL_AQUAE  E=4e-31 s/c=0.44 id=21% cov=72%
----------------------------------------------------------------------------VGGIIRDVLSMGARPIALADSLRFGEfnyHETKRLVKGVVSGISFYGNCIGVPTVAGETVFEPSYKTNPL-VNAFCLGVIPAGRMYRARATREGQLLFLIGSStgrdGIFGAVMASGEFSEDVEEKRPnvqiGDPYFGKKLVEAIMEIvekDLIVGMQDLGAAGLAGSASEIAAKSEKGVELYLENVPLREK-----DMNPYEILLSESQERMLLVVEEENVEKVKEI--ANKWHLEGAVVGKITDDD--TFRAYYKGELVAELPV--------
>UniRef50_B9LUY3(44-329:343) Phosphoribosylformylglycinamidine cyclo-ligase n=12 Tax=Halobacteriaceae RepID=B9LUY3_HALLT  E=3e-30 s/c=0.47 id=23% cov=65%
--------------------------------------------------------------------------------VNDLVAAGVRPVAFVDYLAVDEP-DERFAEQVGEGLARGAELADMELVGGETAVMPDV-IRGLDLAGTCAGLAAKE-AVFDGAAEPGDALVGWRSSGIHSNGLTLAREAATREhaytdpcpfdgyetvgEALLEPTRIYTDLLDPMRDH-GVRGAAHVTGGGWTNLTR--LGANRYVVDDAFEPQPVFEFVQSEGSVSDEEMHRTFNMGtGFVAAVDPDAAESLAAE-------TDGRVIGRVEEG---------------------------
>UniRef50_Q9RXT4(418-721:747) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Deinococci RepID=PURL_DEIRA  E=3e-15 s/c=0.28 id=22% cov=68%
---------------------------------------------------------------------------AVAEAARNLACVGATPLAITDNLNFGNPHRPEVyyqLQQAVQGIADACRALNTPVTGGNVSLYNQYTEGDhkvaihPTPTIGMVGVLPDVTVRASLNLKaAGQTLLLLGHRAEKGWSdsigasqYLETVHGLEAGQVPPVDLDLAQKVVDgtlALIRAGLTDTAHDCAEGGLAVALAEMAIAGGLGLNVSLDA---PASVRADALLFGEAHSRVI----------VAVEDAAAAGAKLDELGLPYAVLGETVEAPKVTIAAP-------------------
>UniRef50_B0SGC9(4-276:302) Thiamine monophosphate kinase n=2 Tax=Leptospira biflexa serovar Patoc RepID=B0SGC9_LEPBA  E=7e-30 s/c=0.49 id=19% cov=52%
--------------------------------------------------------------------------------VSDITASGGVPKECFLNLGLsPHSRQKKWVQTFSKAFRKSLLHYGMKLAGGDTFSSPTTQ-----LTLTVVGTVTK--PWLRSGGKPGDFLYVTGDLGQSQLGYQCLKNNWKDRRYQDAIQRHLLPKSRQVLQtplsRYRIHACMDITD-GLIQDAERLALASKGKLKIQVESIPLHPF---AVEKLGLD-----------------------------------------------------------------------
>UniRef50_C6HZI7(403-693:741) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Leptospirillum ferrodiazotrophum RepID=C6HZI7_9BACT  E=3e-19 s/c=0.34 id=24% cov=49%
-------HPNGG--SADWIYRQFDHEVGtRTLLGPGHDVAIVD---LKEEDRAIAIAQAGF-SHPVSRDPGRGGALLLAKTVTDLAAVGAWPVGVTDCLNFGNPERPETMNDFVQavtGIAGAARRLAIPVVSGNVSFY--NETDGVSIPPTPIlatcGVVAAPRTAPPGSVReEGLHLALAGSLAD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0L864(191-469:481) AIR synthase related protein n=1 Tax=Gordonia bronchialis DSM 43247 RepID=D0L864_GORB4  E=4e-28 s/c=0.46 id=24% cov=63%
--------------------------------------------------------------------------------INDLTAMGARPLGLLDAVGAP---TRSHLTRVVRGIAAAAQAWRTPVLGGHTQVGVHAS-----LSVTALGQTE--RPIPGGGGRVGDTLSLITDLGGSWRPGYQGRQWDSTSARSADELARMARLPAEVRP----AAAKDVSMAGIAGTLGMLAEASGTGAELDVAAVPRPDAARMG------EWLTCFPGYAMLMADRRS--------IEHTPAPTTARACGRLTSSPGVRLRWPDG-----------------
>UniRef50_A3HUE4(5-320:350) Hydrogenase expression/formation factor related protein n=1 Tax=Algoriphagus sp. PR1 RepID=A3HUE4_9SPHI  E=5e-28 s/c=0.40 id=22% cov=65%
--------------------------------------------------------------------------LSVHLMANDMATTGFAPQYGQFVLNLPDSLSNADFSTYWGYIDRFCKEIGVAITGGHTGFV-QGQNSTFAGGGTLITIAPESEMICATGAEEGDVILVTKSCAMTATAILGMSFPETVKNKLGTDVYesacqqfyqtsSLKDGLIAAGESEKfpeITAMHDVTEGGVLGAIYEMLIASGKGGMIENDLIPVGEIASQISKLFDLDPRYCVGAGAMIISCRPDKSAQLIDRL---------------------------------------------
>UniRef50_B7AVF9(38-301:305) Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus ATCC 43243 RepID=B7AVF9_9BACE  E=7e-28 s/c=0.48 id=22% cov=75%
------------------------------------------------------------------------GRYAVIDACNALACRGGEPEGINAAVTIPDSYDEKLLKKLIADIDAQCRTCGTHI--EDVAVSTSQHIRKPVITASAFGRSSEEMPAGMQKAGGNLDIIASGSIGMSGI-MNVLDSHMDEAKKVYADSVINAAAADAGKlsvadraslaAGAGASYLVAAGDGGIYAALWRLAADNGCGFDINLRDIPVKQEIIEMCELFDINPYELSSTGCMLMTA--EDGCGIVDVL--NENGYDAVVIGHTTKEKAKMMHLEDEV-RYLDVPRNE------
>UniRef50_C2AUB9(37-323:341) Thiamine-phosphate kinase n=1 Tax=Tsukamurella paurometabola DSM 20162 RepID=C2AUB9_TSUPA  E=2e-25 s/c=0.41 id=21% cov=70%
-----------------------------------------------------------------------VGRRAIAQNAADIAAMGAVCTGFTVTLGCPPQTPAALVEAISRGVARGAADAGGA-----VAGGDVVRTEQVLLAVTALGDLQGRAPVLLSGARPGDAVAVCGTLGRSaaGLAALDAGRGVDFPEVVEVYRCPVPPLAAGPHAAESGATALTDISDGLLRDARAMAAASGVRIELDGAALRPDDVLADCAAALGADPdawiRTGGEDHALLATFPAGTVPA------------GWRVIGAVLPAEGaagaVTVDGQTGPER--------------
>UniRef50_A8A901(14-280:282) AIR synthase related protein domain protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8A901_IGNH4  E=2e-25 s/c=0.45 id=23% cov=71%
---------------------------------------------------RLVFNVDGFSAKGVlleFMDLRDVGWRGVTACVSDLVAKLVKPKYFLHSVY---GSDVEEVREIVEGIVEAAEEYGLAFLGADTNKGEA------AVDVFCFGLSDLD-PPRLGGARPGDKVVV--PEGCWGCINRCLRGEYW---EHCKRPKVPLELLERLRGYEKYVHASTDSSDGLVISLYKLAWASGVTIALHEPP-PGPLGEEGLYGGEEYLP---------VFVVDPSASEAVEEAVKGRA-------IGEVLPGrPEVVYKG-----RTLDP----------
>UniRef50_Q58811(86-370:452) Uncharacterized protein MJ1416 n=3 Tax=Methanocaldococcus RepID=Y1416_METJA  E=2e-25 s/c=0.41 id=20% cov=61%
----------------------------------------------------------------------------------DIYVMGAEAVALISDVHLADDGDVGKIFDFTAGICAVSEAVNVPLIGGSTLRVGGDMviGDRLVSAVGAIGVIKEGEPTARRNAEVGDVILMTEGSGGGTITTTALYYGWFdviYETLNVDFIKACQNLIRSGL-IKKIHAMTDVTNGGLRGDAYEISKTAKVSLIFDKEKVYktINPKVLEMLEVLNIDPLGVSTD-SLMIICPEEYADDI-------------------------------------------------
>UniRef50_B0G472(24-289:289) Putative uncharacterized protein n=1 Tax=Dorea formicigenerans ATCC 27755 RepID=B0G472_9FIRM  E=2e-25 s/c=0.44 id=24% cov=35%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGGVSVMRQVGEGGIFAALYRLAKEADTGLVVDLKAMPVRQETIEICEYYKLNPYQLASTGNILMIC--DDGEALADALRKEE--TEAAVIGRLTDNNDKIIQNG-EDIRYIDRPAPDELMKI-
>UniRef50_C7M1V0(21-317:342) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M1V0_ACIFD  E=3e-25 s/c=0.40 id=19% cov=63%
---------------AQIVARTFTERVASPIGGFG---ALYEIGGLGGARPTLVATTDGVGTKTEVARAGaryeGLGRDLVAMCVDDLVVTGATPLFFLDYLAL-GRVEPSLVALLVDAMAAALGEVGASLIGGEIAEHPGVlEPGQVDLAGFCVGIVDGDATLGSERVRAGDRVLGLRSPNLRSNGFSLVRRvyadvleavARGETGPLLADGRPLYdaliepsvlyaPLVLEFARAGLLHAAAHVTGGGLAGNL---------------------------------------------------------------------------------------------------------
>UniRef50_C0VZD2(5-302:313) Thiamine monophosphate kinase n=1 Tax=Actinomyces coleocanis DSM 15436 RepID=C0VZD2_9ACTO  E=8e-25 s/c=0.39 id=21% cov=67%
----------------KLIAKMreVLPVGGNTLVWSGDDCA-----EIATTTGSFLISTDVLVEDVHFRIDWssafEVGVRAAQQNMADIMGQGGIVTALVVSLVIPPYLSEDWLCDLVAGFAAAVAPTGAGVVGGDLSR-----GAQLVISVTVCGesvKTPLPGSILRSGARPGDVVAVAGTLGYSYAGLQLLQRGNEQPefALFKQIFKTPQPPLEMGpLAALAGATALMDVSDGLSSDLARLAKASQVSVLLSKTAL---------------------------------------------------------------------------------------
>UniRef50_A4A8V3(412-737:743) Selenide,water dikinase n=3 Tax=unclassified Gammaproteobacteria RepID=A4A8V3_9GAMM  E=9e-25 s/c=0.36 id=20% cov=67%
-----------------------------------------------------------------------MGRIAAQHALSDLYAVGAKPHSAQALVTLPfaaPALLRRDLLMVLQGALSVFDEVGCTLDGGHSMQGPELQLGFAVNGVLAAG----DAPLPKRGAQPGDTLLLSKTLGSGALFAAHMQGladGRHVDDALHALEQ-GNGAAAKIARDYQARAVTDVTGFGLAGHLLEMLGDT-LAADIELGKLKItdgaldamtagvfstlhepnrqaivarwaPPEDLPLLAELLFDPQTS---GGLLMAMPPEKAAQACEALHAQA--VEAELIGT-------------------------------
>UniRef50_A3MXE8(13-305:309) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Pyrobaculum RepID=A3MXE8_PYRCJ  E=5e-24 s/c=0.39 id=22% cov=66%
--------------------------------------------------------------------------------VNDVVSDGFKPVAAVDYVAVSPGL-EDAVPPVFEGLRKAAQRANVAVLGGETAIMPDV-VNGIDVVCTIL----AKRVAAPKRPAPGDYLVALESTGPHANGFSLLRRIFKLGERLCGSTvedILLAPVADygavvEMLKEGVVKAVAHITGGAFAK-LKRVL--GDLGAKLELGNLPCWAEEVVKRGVPREEAYRVFNMGvGMVLVTDtPNDALR-----RAEDLGLRARVVGRVKEEGPVAVDG--------------------
>UniRef50_D0WND5(48-326:375) Thiamine-phosphate kinase n=1 Tax=Actinomyces sp. oral taxon 848 str. F0332 RepID=D0WND5_9ACTO  E=1e-23 s/c=0.41 id=23% cov=48%
----------------------------------------------------------------------------------DAAAMGARPVSFVAALSVPGDRDVEWLVEFARGMGEAARRFGAGVDGGDLTRGPATAG------VTVVGDLSGRPPVLRSGARPGDRLIHCGVLGWSAAGLHFLTSGAvapecasvlpadgerspapngrapDGPDAVVAVYKRPNPPVDLALaacAAGRIRALMDVSD-GLVRDARRMAEASNVGIDIDPAAL---------------------------------------------------------------------------------------
>UniRef50_Q3ZZB9(618-943:953) Phosphoribosylformylglycinamidine synthase II n=7 Tax=Bacteria RepID=Q3ZZB9_DEHSC  E=6e-19 s/c=0.30 id=19% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAACHDLSEGGLGVTAAEMAFSGKLGAHIRLADVPLAEKIER-----EDYILFSESNSRFLVEVAPKHQAEFEKLMSGCDFGL----VGEVMSEPSLEITGRDGKEILLNTPVSEL-----
>UniRef50_C3MZ01(66-370:425) AIR synthase related protein n=13 Tax=Sulfolobaceae RepID=C3MZ01_SULIM  E=4e-21 s/c=0.34 id=18% cov=74%
--------------------------------------------------ENIVVSIDGIHSRLSYFP-FLAGFYATRATLRDIMVKGAYPLGLIVDIHLSDDSDVGMLIDFEAGVTSIGKALNVPILSGSTLRIGGDLVLGDRISGAVgsIGVLKSKDFLRRR-VTKGLKILMTEGNGGGTIATTAIYNGM---PDVISETLNIKDLITCIVvrdhLSSNVYSMTDVTNGGIRADALEVSKITNLSFVIDDEKFlsLINPKVRKMLEEINIDPFGISIDSILIFTDNPDLVKE-----RLAQHNIRSEVIGYI------------------------------
>UniRef50_UPI0001C31B45(8-305:326) thiamine-monophosphate kinase n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C31B45  E=8e-21 s/c=0.35 id=20% cov=71%
----------------EALSEILADEHDRVVRWIGDDAAVVRAR------PYAVTSVDTMVDGVHFrfdggdgtASLADVGHRALAGALSDVAAMGAEAGEAYLALVLPPGLDDAALRELFAAAQQLAAATGTTIAGGDLARGP-----ALVASVTVVGWADAEhELIGRDGARPGDLVGVTGALGGSGAGLELLEGRVGparldpdvARALIRRHLRPQPRIAEGRALAAAGARAMIDISDGIATDAGHIARRSGGRLVLALDRLPLADGVAEVAAALG-------------------------------------------------------------------------
>UniRef50_B1L603(25-289:290) Hydrogenase maturation factor-like protein n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L603_KORCO  E=2e-18 s/c=0.36 id=20% cov=60%
-------------------------------------------------------------------PPSDIGSISFHLPASKISALGADPKFAFGSFFIPEGH-RGVVEDFEREARRYGSRTGSKIVRG---------RRALAI-VSMRGEAR--EIILPTNVKIGDYIALIGVPGAEFLYLISNKkpelfKRLGMEDSIWRWKRALWmltciDAVRTLLTISRVNGLLCVDSRGILESLNKLADISGTGFIISRNRIIFPPELMRIATQMDLDPLELPSSGVTLAAIPK-------------------------------------------------------
>UniRef50_UPI0001C31019(46-359:370) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C31019  E=1e-16 s/c=0.29 id=18% cov=72%
---------------------------------------------------------------------------AVAAIVNDLVCVGAVPAVVNAYFATGDSgwyAQGDRMGQIVRGWERACRDAGAAWGGGESPNLPGlVSPEGIELAGSAIGVVPSGRqPILGAELAVGDEIVIVASSGLHANGASLARMLADRlpqgwstplpsgrafgDALLDPSVQYASLVAALLDQAVPVTYMSHITGHGL-RKLMRADHDLTYAIDALPPVPEVLSFMVDALEMTPADAYGTLNMGaGFAVYVKPGAGAAVVAAAEAAGLSALLA--GRVEQGPRSVVLAPLG-----------------
>UniRef50_P38972(410-640:1358) Phosphoribosylformylglycinamidine synthase n=34 Tax=cellular organisms RepID=PUR4_YEAST  E=2e-15 s/c=0.37 id=13% cov=51%
----------------------------------------------------------------------------------------------------------------------------------------------------GFGTVRPQFALKNTPITPGSCLIVLGGqsmlIGLGGGAASSVASGEGSADLDFASVQRGNPEMErrcqqvidacvALGNNNPIQSIHDVGAGGLSNALPELVHDNDLGAKFD-----IRKVLSLEPGMSPMEIWCNESQERYVLGVSPQDLSIFEEICKRERA--PFAVVGHATAEQKLIVEDPLLKTTPIDL----------
>UniRef50_Q8ZXZ1(3-201:203) Thiamine-monophosphate kinase part 2, authentic frameshift n=1 Tax=Pyrobaculum aerophilum RepID=Q8ZXZ1_PYRAE  E=3e-15 s/c=0.43 id=21% cov=31%
-------------------EKAFLKGLLNILGVEDNDVVYIDDLAIKLDGS--AAST----SKLPFQTWRDFGWRNVAAAVSDLRVKFAAPQFLLASVTAP---SLEVAREIIEGIKEASEAFSVKYVGGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6URF9(401-608:993) Phosphoribosylformylglycinamidine synthase n=8 Tax=Euryarchaeota RepID=A6URF9_METVS  E=4e-15 s/c=0.41 id=19% cov=25%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGISCSVAEMAKECG-GFVVELEKVPLKYPGLEPWEI-----WISESQERITLSVPDEKLNEFMELMK--IRGVESVVIGKFNETDRAVVK---------------------
>UniRef50_Q47XX7(674-988:1320) Phosphoribosylformylglycinamidine synthase n=64 Tax=Proteobacteria RepID=PUR4_COLP3  E=1e-08 s/c=0.20 id=26% cov=27%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTLVRAEKVIAYHDISDGGLFTTVTEMAFAGHTGVDIDISK---------LSNGANDDLATLFNEElGGVIQIRESDVDAIHAILAQHGILENCTDIGR-------------------------------
>UniRef50_UPI0000D5334A(1-225:412) phosphoribosylformylglycinamidine synthase n=1 Tax=Psychroflexus torquis ATCC 700755 RepID=UPI0000D5334A  E=9e-14 s/c=0.36 id=14% cov=52%
----------------------------------------------------------------------------------------------------------------------------------------------------GIGSI-KELHIEKGQPKAGDAVIVLGGpamlIGLGGGSASSTKKTNENSELDFASVQRSNPEMQRRAQqvldkfnerssKNPITFIHDVGAGGISNAIPELAKDTNLGVDIQLEKIYSTDQTMSPMEL-----WCNESQERYVFSIPMKKVPALEFICKRERC--PFSIAGTLTDEK--VIKIKFHDEEIVNLSIDDL-----
>UniRef50_Q8PCQ7(365-578:1348) Phosphoribosylformylglycinamidine synthase n=11 Tax=Gammaproteobacteria RepID=PUR4_XANCP  E=1e-13 s/c=0.37 id=22% cov=33%
--------------------------------------------------------------------------------------------------------------------------------------------DKPIMLAGGLGAIDRNQ-VEKLRLQPGDAVIVLGGpamlIGLGGGAASSVAAGDSAEALDFASVQRENPEMErrcqevidhcvALGTDNPIRWFHDVGAGGLSNAIPELLHDSGVGGVIDLARVP--------------------------------------------------------------------------------------
>UniRef50_Q87DN2(298-578:1322) Phosphoribosylformylglycinamidine synthase n=9 Tax=Gammaproteobacteria RepID=PUR4_XYLFT  E=3e-11 s/c=0.26 id=24% cov=33%
--------------------------------------------------------------------------------------------------------------------------------------------DKPIMLAGGLGAIDR-IHIKKLRLQPGDVIIVLGGpamlIGLGGGAASSVTSGTSTEAldfasvqrdnpEMQRRCQEVIDHCVALGTNNPIRSFHDVGAGGLSNAIPELLHDSEVGGVIDLAKIP--------------------------------------------------------------------------------------
>UniRef50_C9S8T6(250-461:1145) Phosphoribosylformylglycinamidine synthase n=1 Tax=Verticillium albo-atrum VaMs.102 RepID=C9S8T6_VERA1  E=7e-08 s/c=0.29 id=14% cov=25%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAFIHDVGAGGLSNALPELVKDAGFGGKFELRQVHTDDK-----SLSPLQLWANESQERYVLLVNKDSLNRFVSICRRERC--PFSDVGTV------------------------------
>UniRef50_Q19311(323-599:1343) Probable phosphoribosylformylglycinamidine synthase n=2 Tax=Caenorhabditis RepID=PUR4_CAEEL  E=2e-07 s/c=0.21 id=22% cov=28%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AIHDQGAGGNGNVIKELVE--GCGVTVKSDTFQLGDESISLRELWTAEYQ--ENDAAL---VDASLLDALQTISKREKCHV--SVVGEVEKEQRVKLLGKSG-----------------
>UniRef50_Q66675(759-996:1345) Tegument protein n=1 Tax=Equid herpesvirus type 2 strain 86/87 RepID=Q66675_EHV2  E=1e-06 s/c=0.24 id=29% cov=30%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQALVARGLVTAGHDVSDGGLIACCAEMALAGQCGVTLDIQRG-IHPLLVLFSETPG-----------AVLEVPLGNLAGVLEAC--EPFGCFVNQIGTVEPrtGEGHVVVTQGGS----------------
>UniRef50_D0NIT8(329-616:1332) Phosphoribosylformylglycinamidine synthase n=1 Tax=Phytophthora infestans T30-4 RepID=D0NIT8_PHYIN  E=0.0001 s/c=0.17 id=21% cov=25%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNGNVLKEIVEVSNskpgdanrGGARYEVRDILVGDDTLSVLEIWGAEYQ--ENDALLL---RPEHVELFDKICKRE--NCPYALLGQVTGDGHVVL----------------------
>UniRef50_Q016J3(624-757:1078) Putative formylglycineamide ribotide am (ISS) (Fragment) n=2 Tax=cellular organisms RepID=Q016J3_OSTTA  E=0.0001 s/c=0.37 id=26% cov=29%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WSATQKLVDERKISAGHDVSDGGFITAVLEMAFPSTTaGVEVTLP----GDDAMSAC---------FAEELAIVLEVAPENEAAVMSAY--ASVGVTARAIGKVTNDGKCTV----------------------
>UniRef50_C1DUF0(1-332:332) Hydrogenase expression/formation protein HypE n=10 Tax=Bacteria RepID=C1DUF0_SULAA  E=3e-84 s/c=0.95 id=50% cov=98%
MKQIMLAHGGGGEETQKLIKELFFKYFNNEILLSMEDSAVLNI------NSKVAFTTDSFTISPIFFSGGDIGKLAIAGTVNDLSVMGAKPLYLSCSFIIEEGFPFEDLEKIVKSMAEELKKTGTLIVTGDTKVVPRGFVDKIFINTSGLGKVVYEG-VSAHNLSEGDSIIVSGTVGDHGVCIMAQREGIDMQTDLISDCDSVWTLVEDLIKGNvKIKAMRDPTRGGLSAVLNEWAESSNVEIEVLEEKIPVKPQVQGLCELLGLEPYVLANEGRIVVAVSKEDTEKALEILRKNPLGKDAQLIGKVNSkgKKRVILKTSYGSLRIMEPPAGEILPRIC
>UniRef50_A4XJQ3(5-336:336) Hydrogenase expression/formation protein HypE n=9 Tax=Clostridia RepID=A4XJQ3_CALS8  E=8e-83 s/c=0.93 id=40% cov=98%
MKFIQKEHGNGGKQTYELINELFKPIFDSEILKRGDDSSIFDLASKKIG-----VTTDSFVVKPYFFKGGDIGKLSVCGTVNDLAVSGLVPKYITASFIIEEGFPIVDLQKIVKSMKEYADIAGVEIVAGDTKVVEKGSCDGIFINTTGFGVCEKEEKFPSiEKIKGGQVILVSGDIGRHGACIYSHNSEFGFEEKIESDCAPLNRVINELLENVEICYMKDLTRGGLATALNEIAQKANVAIYVEEDKVPVSNEVKALCDILGLDWYYLACEGRFVAIVNRKNEQRALEILRK--YNKEACEIGWIedTEENRVYLRTSFGGTRILDMLYYDMLPRIC
>UniRef50_Q0HUQ3(11-339:339) Hydrogenase expression/formation protein HypE n=38 Tax=Bacteria RepID=Q0HUQ3_SHESR  E=4e-80 s/c=0.91 id=47% cov=97%
---IQLSHGGGGKEMNKLIRELFFAEFDNPILRSEEDAAKLEL------QGATAFTTDSFTVSPLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGVGRILRPN-ISAANVAPGDAIIVSRDVGCHGAAILMAREGLTLESALQSDCATLWPVVEQLIAANiPIHAMRDATRGGLSAVLNEWAAAANVGITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQAAIIGTVSDElpGKVILRTPWNTKRYLDLPQGELLPRIC
>UniRef50_Q58089(2-335:335) Putative hydrogenase expression/formation protein MJ0676 n=40 Tax=cellular organisms RepID=Y676_METJA  E=5e-80 s/c=0.90 id=37% cov=99%
--KITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGlESLDDSATIPIGDKEIVFTVDGHTVKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETSKEAEVAIITGDTKVSDG--VDDIIISTAGIGIVDRGKAIRDCNVQEGDAIIVSGNIGEHGLAILLSREGFDFETNIKSDVAPINKLIERVLEEGiQINAMKDPTRGGLADALNEMAEKSNIGITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNAEIIGYATKEHKGVIIETIVGRRIVDMPIGDPIPRVC
>UniRef50_B2UW48(1-332:332) Hydrogenase expression/formation protein n=12 Tax=Helicobacter RepID=B2UW48_HELPS  E=4e-77 s/c=0.88 id=41% cov=98%
MDSVTLACGNGGKETNALIERVFMPYLKEFIVAFDEDAPKFKAS------GEYCVSTDSFVITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELLKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRY-LKQGQAIIISDTIANHGASLFAMRHEIKLKTNLESDCQLLYPLLKPLfLSDLKIHALRDATRGGLASVLNEWANSSKVKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKNACVIGEVFENpyPSVVLKNAWGFERILEMPEGELLPRIC
>UniRef50_P40599(18-350:350) Hydrogenase expression/formation protein hypE n=110 Tax=Bacteria RepID=HYPE_RHILV  E=2e-76 s/c=0.86 id=47% cov=98%
--RIDLSHGAGGRAMGQLIEGIFHKAFDNDWLRAGNDQ-----SAFSVPGGRMVMTTDGYVVSPLFFPGGNIGTLAVHGTINDIAMAGAVPLYLSASFIIEEGFPLVDLERIADSMGAASREAGVPIITGDTKVVERGKADGVFISTAGIGMAPDGLDLRSDAARPGDAVIISGSIGDHGVAVMSKRENLEFDTDIVSDSAALHGLVADMVAAGGahIRLMRDPTRGGIAATLNEIASQSRVGFRIDEEAIPMKPEVAAACEFLGLDPLNVANEGKLVAVVAPEGADAVLAAIHAHPLGAEAALIGHVVADDNyfVQMVTSFGGGRIVDWLSGEQLPRIC
>UniRef50_C6PPZ0(1-334:334) Hydrogenase expression/formation protein HypE n=6 Tax=Clostridiales RepID=C6PPZ0_9CLOT  E=4e-76 s/c=0.86 id=44% cov=99%
MDKIvTLAHGAGGRQTSELIDQVFKAHFSNPDLTA------DDAAVLNVKGGKLAFTTDGFIVSPSEFPGGNIGKLSICGTVNDLSCMGAKPLYLSCAFVIEEGFPMEKLEKIAAAMEKTADEAGVKIVAGDTKVAGKGQVDGVFITTTGIGQIIDGVNTSGFNAKPGDAIIVTGDIGRHGCTVLLARNEFGIEADVVSDCAPLWGTVKAMLdESKDIHVIRDATRGGVGTVLYEIAEQSKVGIRLDSKSIPVADGVKGVCGMLGLEPLYLACEGRLVIFAPKEVAPKLVDTLHEGKYSKDAAIIGEVTQDmaGRVIVKTEIGAETLLPPPGGELLPRIC
>UniRef50_C3XF65(1-361:361) Hydrogenase expression/formation protein n=3 Tax=Helicobacter RepID=C3XF65_9HELI  E=8e-74 s/c=0.77 id=40% cov=99%
MDIVTLAHGSGGINAAEFVQKVFMPYFKDLMPYANEDCGIFS----SIKDMKYVTSTDSYTINPIFFAGGNIGKLCVCGSSNDVAMMGGKPLYLNIGFIIEEGFNIDLLKQIAESIALECKSLNIKILSADTKVLPKVTDSTeakdklIFINTTCIGSVEKDC-ISAKNLSENDSIILSGKIGSHGARIFLEQNNIAITSNIQSDCASLYPMLESLLQSNiPIHAMRDATRGGLSSVLNEWAISSHACIDIYEEKIQIDSEVHGVCEMLGLEPYDLANEGVCVIAMPKQYAEEVLSLLRGHTLGVNATIIGEVSKvfnpifnlqdskdnkaqiskttyHQKVVLHTKYGSKRFLEYPQGELLPRIC
>UniRef50_B5YJH9(1-332:332) Hydrogenase expression/formation protein HypE n=1 Tax=Thermodesulfovibrio yellowstonii DSM 11347 RepID=B5YJH9_THEYD  E=3e-73 s/c=0.83 id=43% cov=98%
MDKILLGHGSGGKLMYELIKKYIAPIFELPSL---MDSAIVSLNH----SGKIAITTDSYTVSPIFFPGGDIGDLAINGTVNDLAVVGAVPLYLTVGFILEEGFPLSDFEKILSSISSSAKKAGVKIVAGDTKVVDKGKGDGIFINTSGIGVIPEGVELSPLKIEMGDKILISGSIGNHGIAVMSERNGFTFEPPVLSDTRALNGLIDQIMKEFTpfVKVMRDPTRGGLATTLKELALESLKDILIYESAIPLHDTVKGACELLGLDPLYVANEGIFVAIVKADVAEKILQLMKSHPFGEESAIIGEVTgKGGKVLLKTFIGGTRIVDMLPGEQLPRIC
>UniRef50_B7JF80(7-342:342) Hydrogenase expression/formation protein HypE n=32 Tax=Bacteria RepID=B7JF80_BACC0  E=1e-72 s/c=0.82 id=40% cov=99%
LENIILDHGTGGLLSQDLISSIITAKLEGVHLGKMEDSAILEVSS-----RRLAMTTDSFVIDPIFFGEGNIGKVAVCGTVNDLAVSGAKPLYLSLALVLEEGFPIKDLEEILDSIRETAKEAGVYIVAGDTKVVKKGEVDKIFINTTGIGVFEGDVsPFSVNSIQEGDDIIITGQLGNHSIHILSIREGLGFEQRINSDCAPLNHMITELKNHFGdsIHCMRDITRGGLGTVLNEVSETINTGIKIQEKDIPMLAETIMAADMLGVNPMYLANEGNVCMFVSPEVSEEVVRVLKNTKYGKEAAVIGKVtqTKERQVLMEAKSGELKLIELLYGAELPRLC
>UniRef50_D1BLS0(1-335:335) Hydrogenase expression/formation protein HypE n=4 Tax=Veillonellaceae RepID=D1BLS0_VEIPT  E=4e-71 s/c=0.81 id=47% cov=99%
MERVRLVHGNGGRFSHELTDRFILKYFTNDLLAPLHDGA-----QFPVTAGRMAFSTDSYVVQPAFFPGGNIGKLAVCGTVNDLAMNGAIPQYLSCGLILEEGLAFEELDEILRTMSEMAKAANVQIVTGDTKVVKKGEVDKIYINTAGIGMIPDGIDIGPHRVKAGLDIILSGAIGDHSIAVMGQRFGLDLSDSLTTDCAPLNKMVQAVLDKVGtqVALLRDPTRGGLGTVLKEIADQSQVGIKVEETAIPIHEEVQSVCNILGYDPLYLANEGKVVLIVEPSITNEVLKILHSFKEGSEAVLIGKTIDKNigKVGLQTAIGGVRLIDLLGEDQVPRIC
>UniRef50_B4S328(18-350:350) Hydrogenase expression/formation protein HypE n=2 Tax=Proteobacteria RepID=B4S328_ALTMD  E=1e-70 s/c=0.81 id=42% cov=98%
-ESIQLAQGNGGTLTKRLIDHVFKNKANK------DLDLLHDAATVTFDGPYLSITTDSFVVSPPTFPGGNVGALSVYGTVNDLAVVGATPRYISTAFIIEEGFSLSTLKQIVNGMHQAAEETKVAIVTGDTKVVPKGSGGGVFINTTGVGDSRDAPIWDTSLIKAGDHVLVSGSVGDHGACVLLAREDYGLQGQLKSDCGSVVPLIDPIKHLEGVRFVRDPTRGGLSVLLHDVANETGFDIELIENNIPVRPEVASVCEILGFDPFVLACEGRIVAVVAPDISGKVLEHWRSIRNGEQAEHIGVIVKNteskGRVTIVTPMGGRRFMNELEDEPLPRIC
>UniRef50_C8PGA7(3-395:395) Hydrogenase expression/formation protein HypE n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PGA7_9PROT  E=8e-70 s/c=0.68 id=46% cov=99%
-ETILLSHGGGGEEMNRLINEMIFAAFDNEILRANNDSAILNldagagfdrtapssaLNSAASFGGELAFSTDSFVVTPLFFNGGDIGKIAVCGTVNDLAMVGAKPLFLSCALIIEEGLSLSELRRILDSMASTARSCGVRVVCGDTKVVPRGKCDKIFINTSGIGRVLRPARV--QNIKAGAKILLSGDIGRHGAVILAVRDEIALSSELQSDCKPLCAAVEELILQGvKIQAMRDATRGGLSAVLNEFASSSGLEFLVREEDIKISDEVVGVCELLGFEPYELANEGTFVAIVEDDaEANRALEILR--EFDANAAIIGEVREvghdkgefkgslapklgtwdestgasdagtvsenragqfqtphatKGRVILQNAYGSQRFLELPKGELLPRIC
>UniRef50_D1A5C3(24-437:437) Hydrogenase expression/formation protein HypE n=2 Tax=Actinomycetales RepID=D1A5C3_THECD  E=5e-67 s/c=0.62 id=50% cov=100%
-ERITLAHGAGGKATQSLVESLFVAAFRNPALERLDDGAVLDLPAAASGtsgparaasgpsgetgaacademsdaastalgdetvladgtvnpapmsragepgsptvfaddpaatarmsdamataGPRLAFTTDSYVVSPLFFPGGDIGDLAVNGTVNDLAVCGARPLYLSAGFILEEGFEVADLQRIIASMAAAAQRAGVQIVTGDTKVVGRGKADGCYITTAGVGLLDRPITLDAATVRPGDAVLVSGPIGEHGVTIMLARGELDIEADLTSDTAPLNGLTEALLNAtAGVRVLRDATRGGVATVLNEIAQASQTAIVVDEAAVPIRPVVAGACELLGIDPLYVACEGRFVAIVDGAHADKALTVLQTHPLGRDAAIIGHVHDDPPSLVlgRTAFGGTRVIDTLVGDPLPRIC
>UniRef50_C1TK23(1-328:328) Hydrogenase expression/formation protein HypE n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TK23_9BACT  E=2e-64 s/c=0.76 id=40% cov=97%
MGKLNLGQGSGGRLTSELIGK-FKAQFDDVNVQR-------DLEDCTMISPEWAVTIDGFTVSPMDFPGGNIGKLAICGGTNDLAVRGIEPKFVTLSVIAEEGLDEEELLRYGRSAASVCHGLEVKLAAGDTKVVPKGTVDGLFLTVASMGQ-PLGKPLGMDHIKPGDRLAVTTSIGRHGATIGSIRFDLNVEG-LSSDCAPLWPLVKPLAVLPGVRAMRDCTRGGLGTTLCEWAEGTGLGIEIDESSIPIDEEVSSVCDILGFDPLHLACEGCALIAYSPDDEDRIIEILRAHPSGIQATSIGTVVEGHPsmVGMRTKAGGMRVVDMPVGELLPRIC
>UniRef50_B6YVE6(5-329:330) HypE n=9 Tax=Thermococcaceae RepID=B6YVE6_THEON   E=2e-55 s/c=0.67 id=26% cov=93%
-----------GKIPPEKLREIVFNRLGAPGERVIAKSdLGVDATAIDFGSSVLVASTD-----PITGAEEKIGFYAVHINANDVATFGAKPKWFLVSILLPENSDDALLVKIMDELHESASKLGVAIVGGHTEVTPG--LDRPIVAGTMLGEVPKEKLVTSNGAKPGDAIILTKWAGLEGTAIIASERGKELEkafgKEFVEKAQSLIEMIsvvedALTANEIGVNAMHDPTEGGVANGLHEMADAAKLGFRVYAERIPIRKETLKICEFYDLNPLALISSGALMIAAPKEKADSIISALKR--KGINASVIGEFLEDKESRVMVDNGKEKPLERPESDEL----
>UniRef50_D2RDT5(3-344:344) Hydrogenase expression/formation protein HypE n=3 Tax=Archaeoglobaceae RepID=D2RDT5_ARCPR  E=4e-55 s/c=0.63 id=34% cov=97%
---IRREDGAGGKYMAEFLKKHIISRFGDNRLGEISLADMDDSSDFDG----YVFTTDSYVVSPPIFRGGSIGSLAVCGTANDLAVMGAKPYAMSLALIIQEGFKVSDFEKIMNDVERWVKELDVKLITGDTKVVSANV--EIIANTSGIGIRNsaldhnisvvkeyrdyPYNWVRDCGLREGDAIIVSGCVADHAVAIMLSRE-FDFDIDVQSDVYPVWLFVKEALEVGGITAMKDPTRGGLANALNELAEKSGVGIYIEEERIPIREEVKGFCEVLGLDPLSMANEGKVVMGVVEDMAEDVLKALHKAGQKY-AEIIGYATSEFEEVVVETEiGTKKVLPPPTADPIPRVC
>UniRef50_Q15W96(5-294:336) Thiamine-monophosphate kinase n=2 Tax=Alteromonadales RepID=Q15W96_PSEA6  E=3e-54 s/c=0.74 id=29% cov=46%
----------------SLIDTYFRDvsfQRKDVLLGIGDDCAI----TQIPAGQALATTTDTLVSGVHFLPDADpkaIAQKAIAVNLSDLAAMGAEPAWLSLSLSLP-NVDEQWLKAFSEGFRELTEYYSVQLIGGDTVQGP------LAITITAQGFVAADQALKRSGAKPGDFVYVTGSLGDAG------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3II30(7-300:326) Thiamin-monophosphate kinase n=3 Tax=Alteromonadales RepID=Q3II30_PSEHT  E=2e-52 s/c=0.71 id=27% cov=50%
----------------ELINRYFKGRGitrRDVNLGIGDDCALV----TVPQNCQLAITTDTLVAGVHFFDdiePRALGHRALAVNLSDLAAMGAEPTWVSIALTLP-SIDQQWIEELTDGMHEIAEYFNVQIIGGDTTQGP------LSITICAKGTVPEGTALCRNGAKVGDWIFVTGPLGDAGLAIESRKQGLTIEPE---------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1C275(20-334:342) Thiamine-monophosphate kinase n=1 Tax=Sphaerobacter thermophilus DSM 20745 RepID=D1C275_SPHTD  E=1e-49 s/c=0.63 id=21% cov=82%
----------------------------------GDDAAV----WRPRPGRDLVFTTDILVQNVHFrldwMDWQAVGHKALAVNLSDVAAMGAQPRLALVSLALTGSERDREVTDLFRGMNALGRRHGVVVAGGDLSASP----NGVIVSVTVIGETSAGRraVMTRDGARPGDIIGVTGPLGMAAAGLRVFQQQlltLDGNPAMREAYSRPKPRVREgrLLARAGVRAAMDLSD-GLLGDLPKMCQASGVSAVIDIARVPIPNAIKWNFDDWFDLALRGGEDYELLFTAPPAVFARVCRAFRLAGLHGP-WRIGEIVkagaKGPEVKIREASG-----------------
>UniRef50_Q8ESJ0(5-312:322) Thiamine monophosphate kinase n=1 Tax=Oceanobacillus iheyensis RepID=Q8ESJ0_OCEIH  E=1e-49 s/c=0.65 id=22% cov=84%
----------------SFIDSIKPTYYRQPSLlkGIGDDAAVFRSS------KDIVTAVDTFVEDVHFsrstMEPYHIGYRALGANISDLAAMGASPSFYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDTV-----SGKQLTISITVIGYTITNKARYRQHAKEGDIVFVTGTLGDSLAGFHiltsdNENNRYVDQDFYIHRHRKPEPRVAFAQALESLdRVSLNDVSDGIANEASEIAEASNVSIVLRENDIPVAPSFYQFTYEQQYQWkLSGGEDFELLGTVAKGDWAVVNEA--AEKTNTQLTVIGSVVEEEK-------------------------
>UniRef50_A7BRC9(5-332:351) Thiamine-monophosphate kinase n=1 Tax=Beggiatoa sp. PS RepID=A7BRC9_9GAMM  E=3e-49 s/c=0.60 id=27% cov=46%
----------------DVIAHYFsqnFPKRTDVILGIGDDAAL----CSVPNYMQLAVSIDTLVEGVHFpvtTSPEDIGYKALAVNLSDMAAMGATPAWMTLALTCPK-VNETWLKRFSQGLLELAQSAQVSLIGGDTTQGP------LTITLQISGFVPIGQALRRDGAQPGDGIYVTGTLGDAG------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q2JTF1(42-328:340) Thiamine-monophosphate kinase n=11 Tax=Cyanobacteria RepID=Q2JTF1_SYNJA  E=2e-48 s/c=0.68 id=22% cov=66%
---------------------------------------------------------------------------AVAANLSDLAAMGSRPRALVVGLGLPGSTPVAWVEELYEGMRACCARWGAELVGGDLCRSPQR-----FVAITALGSVQPGRAIERRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSAtaaqrqqLIRAHQYPRPRLDVLslleALPGPLRLAGMDTSDGLADALVQVCQSSGVAARIAAERIPISVALRQAFPAQALEWaLYGGEDFELLLSAEVSVAKHLLEKL------PGAAWIGEVT-----------------------------
>UniRef50_D1VUU5(4-324:325) Hydrogenase maturation factor n=1 Tax=Peptoniphilus lacrimalis 315-B RepID=D1VUU5_9FIRM  E=4e-48 s/c=0.60 id=23% cov=94%
-----------GKVSNNDLEKYVFKNINSHRKEVLTKsSIGIDTAVLDFNGDLIVTSVD-----PITGANKNLGYLAINISVNDVSCQGADPVGVLISILLPAESKLEDLNKIMEDADRACRQNNLEIIGGHTEVTD--AVNKIVLTTTVIARVNKNKMPKISSIKVGDVIAVSKDIGLEGTSIILEEKGNEFlsEDELRKESIDIKDlsvlREAKIAVDFNVKYMHDVTEGGIYGALWECSEAIGKGIEVDNIKIPVKDVTKKIGSHYNINIYGLISSGSMLMVFNKEDFKAYKKAC--FEKNIKITQIGEVTEENKKILID-NGKKIEIPEPASDELYKI-
>UniRef50_Q5FH10(5-307:316) Thiamine-monophosphate kinase n=4 Tax=canis group RepID=Q5FH10_EHRRG  E=6e-48 s/c=0.64 id=19% cov=70%
-------------------------------------------------------------------------KKALRSNLSDIAAMGAIPYAYCLGLVLPNNISNNWWQDFSNSLREEHKIFDIILLGGDTTSHKNNI---IIISITAFG-INHGNLLKRSGAKIGDFIYVSGTIGDAALGLLVYQNIIKKnYENLKNKYDIPQPRINLGIDINQIASSCIDISDGLIQDMEHICHASNVGASIYLNKIPLSNETKEIianTPRYINSVLSGGDDYELIFTANPKFSDSIKEISKKN--GVKITKIGKITEGNSVIL----------------------
>UniRef50_B0KL72(5-305:322) Thiamine-monophosphate kinase n=13 Tax=Pseudomonadaceae RepID=B0KL72_PSEPG  E=8e-48 s/c=0.64 id=24% cov=86%
----------------ELINHYFAAApcaqgGEGVALGIGDDCALLDL----PPGEQLAVSTDTLVAGVHFPvacDPLLLGQRSLAVAASDLAAMGATAIGFTLALTLP-DVGPGWLSAYADGLSRMAQRCRMSLIGGDTTRGP------LSITVTVFGRVPVGQALRRSGARPGDLLCVGGSLGKAAGALPLVLGEREAPAAqaepLLAHYWSPMPQLTLGALLRGRATAALDISDGLLADCGHIAKASGVALEVNLAQVPVSPALEAFLgrEAAVRAALTGGDDYVLAFTLPPEALAPL-----AAFDTIEVHTIGRVLEGQGVTLRDAQG-----------------
>UniRef50_B9KYQ7(9-336:343) Hydrogenase expression/formation n=2 Tax=Thermomicrobia (class) RepID=B9KYQ7_THERP  E=9e-46 s/c=0.57 id=28% cov=94%
-----------GKLPPQLLAEFLGNLSPDPSVLLG-PGIGHDAAVIQIDTIRLVFKSD-----PITFATEAIGWYALNVNANDVACLGARPRWFLATVLLPEGTTAHDAQVILDDLARAAERLGVSVVGGHTEI--TVGLDRPIVAGTMIGELTTEYVLSPARVRPGDALLLVRGIAIEGTALLAREcrqtLERMLDQDLLARCRRflyepgisIVPAATLLLERLGedLRYLHDPTEGGLATGLHEVAVACGTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGALLAVVTPESVEHALDTLAQHD--IPATQLGWLDPDPGRRVLIGSTGERPLPVFQVDEVARL-
>UniRef50_Q7NG75(9-327:328) Thiamine-monophosphate kinase n=1 Tax=Gloeobacter violaceus RepID=Q7NG75_GLOVI  E=4e-44 s/c=0.57 id=23% cov=85%
---------------RGLIARLgrFFGQAPHILVPGGDDAAVV-----APGSGALVATTDLLFEDVHFGDrttgPFDVGWRSAAANLSDLAAMGAAPFGMLVGLGLSPGTSVEWVEAFYEGFTACSAPVGALLLGGDTCRAKSR-----TVAVTALGTVDPRRILRRNAARPGDALVVTGHLGASRAGLAVLLEAERyahlgspVREAVVAAHRRPKPRLEvpPLVFALSGRAAAMDTSDGLTDAIAQVCAQSGCGAVVDLAVLPIDAATAQVAGKQAIAWaLGGGEDYELLIALEPGAAVQLVERLAA--IGIGGAIVGRAVAGDRVV-----------------------
>UniRef50_Q8TVM0(14-329:334) Selenide, water dikinase n=1 Tax=Methanopyrus kandleri RepID=SELD_METKA  E=5e-44 s/c=0.57 id=24% cov=88%
-------HGUACKLPQGDLEDLLKGVELPEEGGRVEVGVGDDAAVIRVDGGYVIQSVDFFT--PIHPDPYTQGRIAANNSINDVFAMGAtEVLSVLVVSGFPRELPEEDAREMLQGFADQCREVDALIVGGHTIMNP-----WPILGGCVTGFAE--RYVTVGGAEPGDVLYLTKPLGTQPAMAALrlpedVRKQFLTDSELEEavdlavevMTEPLKDAAEAALEV-GVHAMTDVTGFGLKGHAGEMAEASGVRVVI--ERLPVIPGTTELSRALGYGLERGESaetAGGLLVAVPEEHAEDLEDAFERRD--VWYRRIGRVEEGSGVEVRG--------------------
>UniRef50_D1C5Z5(14-347:359) AIR synthase related protein domain protein n=7 Tax=Chloroflexi RepID=D1C5Z5_SPHTD  E=4e-43 s/c=0.53 id=25% cov=94%
-----------GKISPEVFEQVIKPRLGRHRPEVLvGPQHGVDVGIIDIGGGRvMAVTTDPFFIVPQ-YGWERAAWFAVHILASDAATSGLPPTYFVVDLNLPRNITSEGLEALWHAVDATCKEIGMAIVTGHTARYDGT--DYPMVGGAMVMAVgERDRYVTPTMARVGDAVIVTKGAAIEATGLFGVTFPDRIAAAYGQEIARQaeetfyqmsvvkdaMTAVEVGVRDAGVTAMHDATEGGVWGGLYEIAVASGVGMVVEQNAIVVSPAAQAVCDLFGMNPYAAISEGTLIITCRPEKAGAVLTRL--EDAGIAATQVGEITpPEEGIRLV-RDGREEPLEHPRVDP-----
>UniRef50_Q2RZV6(20-344:360) Thiamine-monophosphate kinase n=1 Tax=Salinibacter ruber DSM 13855 RepID=Q2RZV6_SALRD  E=2e-42 s/c=0.54 id=24% cov=54%
--------------------------------------------------------------------------------VSDVVAMNASPRYATVSIGIPQNVSVEMITTVYEGLKQACDAYDMHIVGGDT-----NASHGLSLSISVVGAAAEEDVVYRTGAQVGDKICVTGDLGSSYAGLKVLLRNRERlqeqEEDFEPDLDPYSYVIRRHLAppaqlktvrdwgdAGVQPHALIDISDGLSAEVHHICEAGDLGAQLYEPALPIDPETRNTATDFGED-----------------------------------------------------------------------
>UniRef50_C0R0M8(25-355:358) PRK00943: selenophosphate synthetase n=2 Tax=Brachyspira RepID=C0R0M8_BRAHW  E=3e-42 s/c=0.53 id=22% cov=77%
-----------------------------------DVDIGDDAGVYKIsDDNALIFTVDYFP--PVIADPYGFGQIAACNSISDIYAMGGEPKLALNITMFPKDDSLNILANMLKGGQDKATEAGVLVVGGHTITDASVKY-----GMAVIGFANPNKITTNAAAKEGDIIIFTKPLG-TGACLAAMRQGLIKEshiEDVFESMKTLNKKACAVMNKYNVKCATDITGFGLIGHAYKMAKASDVTIEIQSSALPmfnktyevldmgcipgaaftnmryvgdnikVDDNVDYNLKMLSFDPQTS---GGLFICADKSNAENILADLWREGIDC-ACIIGKV------------------------------
>UniRef50_Q73JP8(20-352:354) Selenide, water dikinase n=3 Tax=Bacteria RepID=SELD_TREDE   E=1e-41 s/c=0.52 id=20% cov=87%
--------GUGAKLSAGALDKLLknFSVRNDDNLLVGFNTSDDAAVYKINDKTALISTIDFFP--PVSGDPYIFGQVAAANSLSDIYAMGGEPKLALNLFCITKDMPEDMIKEILRGGFDKVYEAGAIVCGGHT-IYDDSPKYGLAVN----GFVHPKKILENSTAKEGDVLILTKPIG-TGILLTASKADMSPPEELDRCykiMAFLNAKARNIMVKYKINACTDITGFGLLGHLYEMGKGSGMSIEVDYKSVPIYKSVIESAEMgmmpagvysnrnfvgdnivfenvplayqdLMFDPQTS---GGLLISVDKEDAAALYEELSQALENTPCgkpAIIGLVTKR---------------------------
>UniRef50_A4WH94(4-321:335) AIR synthase related protein domain protein n=5 Tax=Thermoproteaceae RepID=A4WH94_PYRAR  E=2e-41 s/c=0.54 id=27% cov=80%
-------------------------------------AIGEDAAVVDLGGKYLVAHTDPITGSVNL-----LGSLAVYVPTNDVAVRGVEPMWLSVALLLPPGASDDLLDAITRQMDMAARRLGVTIVGGHTEVTTAVTRPVAVVTAMGVG----SRFVSTSGAKPGDVVVMTKSAGQETASILASDFAEEalrrgVPAEALERARGLIAEIsvarEALALADLATSMHDPTEGGVANGLAEIAYASKVSIDVRRKDVVVYREVEALCRAFRIDPLETLSSGVLLATVPRGRLGEALERLQK--LGVPHAVIGEVKPPSGYLVK---------------------
>UniRef50_A5UMR0(27-296:306) Thiamine monphosphate kinase, ThiL n=3 Tax=Methanobrevibacter smithii RepID=A5UMR0_METS3  E=4e-41 s/c=0.63 id=19% cov=65%
--------------------------------------------------------------------------------VSDLAAMGATPLGFLLSIALPKDFEVDDFKQIIKGVLKACEYYGICLIGGDT-----NEASEIIISGTALGLC--DNPLMKNTSEKGDLVVLTGKIGLAALGFNLENDNIYTKKALE-----PIAKIKEGINIKnsGGTSATDITD-GLASELYEMKRE-DIGFMIYEDKLDISGEFKSLAAElnlnYLDLLLHVGEDFELVFTINKKNL---------HKLNFKYLVIGEVTDSKKVEIRLSDSTVR--------------
>UniRef50_D1VW68(12-357:375) Thiamine-phosphate kinase n=2 Tax=Prevotella RepID=D1VW68_9BACT   E=9e-41 s/c=0.49 id=20% cov=54%
--------------------------------------------------------------------------------ISDVFAMNGTPRQMLVSLAIDKRFSVEDIEAFYNGLRMACNKWKVDIVGGDTTSSRTG----VAISITCIGEAKSEEIVYRNGAKDTDLICVSGDLGAAYMGLMLLEREksvyykqvdeirtkilkakeqknqalvtklthdlnslgnfqpdfAGKEYLLQRQLQTEARgdIIETLRAAHIHPTAMIDISDGLSSELLHICKESNCGCRIYEKNLPIDYQTAVMAEELNLN-----------------------------------------------------------------------
>UniRef50_B1H0F2(1-286:331) Thiamine-monophosphate kinase n=1 Tax=uncultured Termite group 1 bacterium phylotype Rs-D17 RepID=B1H0F2_UNCTG  E=1e-40 s/c=0.59 id=21% cov=69%
----------------DMIKNQFADSKDNKNIVAG---IGDDSFCFKSGKNNICITKDMLVEDVHFKKDWTnpqeIGRKSIEVNVSDIAAMGnVKPEYAFIGLGLPPKTSEIFIKNLYKGFKKACDKYKMAIAGGNTVR-----ADKTIISVTIVGIgIGRERVIKRNGAGIGDLIGVTNTFGDAGAGVALLYkygtkhKYNKYEHFLISKQNNPKARLKEAQKISKHLTSLTDASDGLYISVDLLAKDSGKGAEIYMDKIPVSSSLK--------------------------------------------------------------------------------
>UniRef50_UPI0001C1612E(20-338:343) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Nostocaceae RepID=UPI0001C1612E  E=4e-40 s/c=0.53 id=19% cov=87%
------------------IRNLVHSTFRPEVLGGLGGFSGCFQLPTGYHEPVLVSGTDGVGTKLKIAQilncHHTVGIDLVAMCVNDVLTSGAEPLFFLDYVA-TGKLEGEQLTQVVSGIAQGCKLAGAALLGGETAEMPGfYQVGEYDLAGFCVGIVEKSKMLDGSQVQIGDLVMGLASSGIHSNGLSLVRKiisdgGFAWDHTpelfhgktlgstfLTPTRIYVKSVLSALHQGLEIHGMAHITGGGLPENLPR-CLGSNQSVKVHPASWPIPPVFKWLADfgsVGAEAMYNTFNMGlGFVLILPPTQAQQAITHFQSQ--HIPAFTIGEVVGGSGELI----------------------
>UniRef50_B1HTV6(46-348:351) Phosphoribosylformylglycinamidine cyclo-ligase n=373 Tax=Bacteria RepID=PUR5_LYSSC  E=4e-40 s/c=0.55 id=22% cov=70%
--------------------------------------------------------------------------------VNDIVAQGAEPLYFLDYVALGKA-EPAKIEQIVKGVADGCVQSGAALIGGETAEMPGlYEEDEYDLAGFAVGACEKSAIVTGERIVEGDVLIGIASSGVHSNGYSLVRKIVFADrqyavdaivenyedlgpigEALLVPTKLYAKPVLAALKAADVHGCAHVTGGGFYENLPRMMPE-GLATEIDLGSWPvlrIFEFLKDKGQLEDKDLYNVFNMGiGFVIAAPAAEADKVMAAVEAN--GEKAYTIGRVIKGNGVVFNGT-------------------
>UniRef50_A0RWJ0(23-306:400) Thiamine monophosphate kinase n=1 Tax=Cenarchaeum symbiosum RepID=A0RWJ0_CENSY  E=5e-40 s/c=0.59 id=24% cov=71%
---------------------------------------------------------------------------AVVSCTSDLAAKGVRPRYGLVSVTLPLDCTKNTVSGLAGGLAAAAKKFGFKFVGGDT-----GGGAELSISVFLAG--PADRIVPRGGARSGDMIYVTGPFGYPSAGLQIIMGGAsskkGFAARAIRAQLRPEPRLEFGACAARLLTSCMDSSDGLSSTLHEMARQSGTRYTLY--RLPAGAGIMGFASDNGLDgdslVLDGGEEFELVFTAHPRNRKRIEKTARK--LGVPMQEIGRVEQGRGVWLASGDGMRRIKD-----------
>UniRef50_A1APP9(16-341:348) Selenide, water dikinase n=10 Tax=Bacteria RepID=SELD_PELPD   E=5e-40 s/c=0.51 id=25% cov=69%
-----------------------------------------------------------------------FGQIAAANALSDIYAMGGVPKTAMNVVAFPAKTmDISVLRSVIEGGLDKMREAGVVLVGGHTVEDS-----ELKYGLSVTGFIHPDRILTKKNLQTGDCLILTKPLGTGivSTAIKAGLAGSDLTERVIRNMTALNRDAALVMGDFTVHACTDITGFGFLGHLAEMVVDSGCGVRIIAADVPHYPEALEWADMglipggaynnrdfrgmfvdfgaavsrrfrdLLFDPQTS---GGLLIAVAPNEAEQLVAALKATGI-ECAAVVGEVVEEP--------------------------
>UniRef50_C6A0I0(400-681:713) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Thermococcaceae RepID=PURL_THESM  E=7e-29 s/c=0.46 id=22% cov=66%
---------------------------------------------------------------------------AVAEVVRNLASVGARPLALVDNLNFasPERPEVYWsFIETIKGLADAAKAFGLAYVSGNVSFYNEVGKKPIKPTpvVAGLGKVKLENITTMDFKDKGDLIAVVGTTKKELGGSELYRifginKGIAPRVDLEREKQNVEGILKAI-ELKLVKAVHDVSKGGLAIALIEMAISGNKGFEVDIEKVP------AEGGLSPLEVLFSESHGRFLISFEEKNLEKIKAIFD------EFAVIGRVAEE---------------------------
>UniRef50_A3PDW4(14-310:326) Putative uncharacterized protein n=1 Tax=Prochlorococcus marinus str. MIT 9301 RepID=A3PDW4_PROM0  E=3e-39 s/c=0.55 id=15% cov=80%
-----------GIESKKDIQSA-AKTFSHSPFSQLGKSAmlGDDAAVIPKQSGLLLMASEGISPSLVEKEPWFAGWSSVLVNISDIAAMGGKPLALVNSI-WSDKNDLEKHNQILSGMNFACEKFNVPMVGGHSNQKSPYSA----LSVSILGLVDGPILSSRFAESEDELWIIANKDGCFFKDYPFWDAATKASATLLRKHFSLIPF---LAKKNIIHAAKDISMGGITGTAVMFAESAGKTIEIDLEKIQRPEGVTEF------DWLTCFPSYGFLCAIKPSKVPFLKEALRAYE-----------------------------------------
>UniRef50_D2VMQ3(391-731:737) Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VMQ3_NAEGR   E=5e-39 s/c=0.48 id=19% cov=79%
-----------------------------------------DAAVYKINDHvAIVSTIDFFA--PIVDNPYDFGAIACANALSDVYAMGGKPQTALSVVAFPSRtLPIEILQEILRGSIDKANEAGVAIVGGHSIDDE-----EPKFGMSVNGIIHPDKIFRNVGCEEGDLLFLTKRIGTGVITSAMKLGNVPYESETaqsaINSMKTLNRDTSyVLREMKSVSSCTDVTGFGLLGHLKEIMKGSreiceenkDLVAQLNAKQIPLLDssclslmrivipggtktnlenvqqFVEFASTLSKEEQLILADaqtSGGLLFTISPDEEEKLVNSFK--EKNLNLWKIGEIVKKPNSVL----------------------
>UniRef50_A9A3T2(3-303:310) Thiamine-monophosphate kinase n=1 Tax=Nitrosopumilus maritimus SCM1 RepID=A9A3T2_NITMS  E=1e-38 s/c=0.54 id=19% cov=84%
------------------IIKIFQRKLGNKN---SEDVEIFKLKQnIIAKTDTLVQSTDI----PPKMKLGEAARKSVVACVSDFAAKGVKPQYGIISINFPSNISRSKVEEAATGFRKACSEFGISILGGDT-----NAGKEIVFNVCLFGSAEK--IVPRNGSESKDLIFATGPFGYTGAGLSILlykkKGKREFVAKAIKAVTHPKPRVDFGVKNKRYFTSSMDSSDGLSTTLNEMAKQSKKKFVINNSPHKKDLGEFAKSNQDNL-VFHGGEEYEFVFTINPKHKKTILKNAKS--LRTPIIEIGYVTTGKGVILQ---------------------
>UniRef50_Q46F25(44-352:715) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Methanosarcinaceae RepID=PURL_METBF  E=2e-38 s/c=0.52 id=20% cov=88%
--------------------KTFTSKGENVIIGPGDDAAIIKF----DDGYVLAIGMESHN-HPSYVDPYNGAATGIGGIVRDIISMGARPIALMDPLYFGPLDTPKnmfLFEQIIKGIAGYGNCIGVPVVNGETFFDRRYSGNPL-VNVVAVGLCREEEVITARSQKAGNKLVLAGSStgkdGLGGASFASRDLSESAEAEDRPSVQVGDPYTEKLviemtleaMEKGYIKSCKDLGAAGLGGASAELAAKGGLGAHITADAVTQREPNMNAYEI-----LLAESQERMVFEVAPEDVDAVLALV--AKYDLNGAVVGYLTEKPNYTVE--FKGEVVVDIPI--------
>UniRef50_Q6KZH8(1-325:334) AIR Synthase n=1 Tax=Picrophilus torridus RepID=Q6KZH8_PICTO   E=2e-38 s/c=0.50 id=23% cov=85%
--------------MTGKISREFFESNIIKRLGFLRDEVVvppengVDVGIVRLGNGYLAVTTDPFYIDPVF-GLKKAAWFGFHILLSDIYTSGIPAMYMSIDLNLPQSMSDDEFNEIWTVINDESKKYNVMVVTGHTARY-AGVSYPMIGGVTLMGY--GDRYITTKNAGDGDIIIMTKTCALEASCILSYTFPEYIEKHLgMDTLKKLNDLFykmtcvnEEILSidfgLDKITSMHDATEGGIINALYEIGKASGHGVIVNKNNINIDESVSRVTKLFNIDPLRSISEGTLLITVKRNFADELL--LKLRSAGIDSYIIGE-------------------------------
>UniRef50_C7MPH9(9-314:321) Selenium donor protein n=2 Tax=Coriobacteriaceae RepID=C7MPH9_CRYCD   E=1e-37 s/c=0.52 id=23% cov=47%
------------------------------------------------------------------------------------------------------------------------------------------------------GVVHPDHIIRNGGARPGDVLFYTKKIG-TGILTSAFRAKLETDESMREAinsMMELNKYGAAAMRRVRTHAATDVTGFGLAGHLHEMLEASGCAARLQWDALPLFDKVFDYAcaycrpgktfsiiqWAQPFVPQGTLDDndydnrmavlcdpqtsGGLLVAVDP-ADADAFDAAFFEQTKRHASRIGEVIDGP--------------------------
>UniRef50_B8KWB4(7-304:312) Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium NOR51-B RepID=B8KWB4_9GAMM  E=5e-37 s/c=0.53 id=27% cov=84%
----------------ELIGRYFASLGGGDRiaLGIGDDAAVFD----VPEGEQCVVSTDTQVEYVHFFPetlPEDIAYRAVAAAASDLAAMGASPLGMTLALTLPEA-DELWLHGFSQGLAAAVRDLALPLMGGDTTQGP------LTITITVHGSVPRDAAVTRGGARPGDRLCVTGTLGDAAAALALQRGELSGDrlpeaedvEWLLSRFNRPIARFEWLSFLRAHGSAAIDISDGLLADAEHIAAASGVALTIDSTAIPLSDALRRAApsEARLFEWaLGGGDDYELLCTVPAGC-----------QIPDGLAVIGEVVVGQGVQIDRPTSG----------------
>UniRef50_D0LRS0(75-366:381) Selenide, water dikinase n=1 Tax=Haliangium ochraceum DSM 14365 RepID=D0LRS0_HALO1  E=3e-36 s/c=0.53 id=25% cov=78%
----------------------------------GDDAAVVRLPGDAASGRALVLTTD--VIAPLVDDAESFGAIAATNAVSDVYAMGGRPLYALNLAFFPDqSLPLEVLRAILRGGARACERMGVAIVGGHTVRDS-----ALKYGLAVTGEVDSERAWRHEGGRAGQELVLTKALGTGVLGTAIKRGEasAADSAAAIASMSTANRAAAEIGQRFAVSACTDVTGFGLLGHLRNIVRASAVDAELELDALPLLPGALEHARagrvpggskanlAFLAPMLAGADEvdpallalaadaqtsGGLLLCVAPEHSAAMLEALRA--SGLPAARVGR-------------------------------
>UniRef50_Q9UX29(20-320:323) Phosphoribosylformylglycinamidine cyclo-ligase n=12 Tax=Sulfolobaceae RepID=PUR5_SULSO  E=4e-36 s/c=0.51 id=16% cov=85%
---------------HNMISQIISSTYKNTIIG-----AGHYSGVIKIGSLNIAMHTDGVGTKTFLALQTRIikpvGIDCVAMNVNDLICVGAKPVALVDYIALERPMD-NVVNEIIDGIVQGAKEADVEVIGGETAIMPDV-IRGFDLSCTAIGVV--DKLKTGAEIRPGDYVLGLESSGIHANGYSLVRKlieegKLSLDEYKNELLKPTKIYVKPILEVMNmIKGAAHVTGGAFS----KLKRLTSYKIVLNMPDPPQIFKTIEKAGVAHEEMYKVFNMGiGIVLFVSEELMKEVKTKLEGYG---TVYELGRVYNGNGITIKT--------------------
>UniRef50_A4FWS4(37-338:349) Phosphoribosylformylglycinamidine cyclo-ligase n=12 Tax=Methanococcales RepID=PUR5_METM5  E=4e-36 s/c=0.51 id=16% cov=67%
--------------------------------------------------------------------------------VNDAICIGAEPVALVDYMAV-EDITEDIASQIGKGLNDGIKESNINLIGGETASLP-NMIKGVDLAGTVLAVVKKDEIVSGKEVKPGDLIVGLRSSGIHSNGLSLARkvffdianldvnsklsHGKTVAEELLTPTKIYVKPVLEMIKQVNVKGLAHITGGGFRK-LKRLNKEVCYKIDELPEILPIFKEIQNLGSVADEEMFKTFNMGiGFCVIVDKEDAEKIIEI--SNHHNIPAFVIGKIED----------------------------
>UniRef50_Q21MC3(25-343:352) Phosphoribosylformylglycinamidine cyclo-ligase n=168 Tax=Bacteria RepID=PUR5_SACD2  E=5e-36 s/c=0.48 id=21% cov=67%
--------------------------------------------------------------------------------VNDLIVGGAEPLFFLDYYA-TGKLSVDVAASVVEGIGAGCELSGCSLVGGETAEMPGmYEGEDYDLAGFCVGIVEKSKILDGSKVAAGDVLLGIPSSGPHSNGYSLIRKVLEVSGaslddkvgdttlgqALLEPTRIYVKPLLELFKNVQVNALSHITGGGLLENIPRVLPE-NTRAQIDCASWELPPVFKWLQEQGNInavEMYRTFNCGvGMIVCVPAAEAANAIAQLK--QSGEDAFEIGKIV-----------------------------
>UniRef50_B3QXM6(13-326:329) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Bacteria RepID=B3QXM6_CHLT3  E=9e-36 s/c=0.49 id=21% cov=30%
-----------------------------------------------------------------------IGTCLVNHCTNDILVCGAKPLYFLDYYAC-GKLSPDDAENVVRGIVNGCKENDAALIGGETAEMPGiYGADDFDLAGTIVGVVEKDQILNGRSIKEGDVLI---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A1RXF5(1-299:312) Thiamine-phosphate kinase n=1 Tax=Thermofilum pendens Hrk 5 RepID=A1RXF5_THEPD  E=1e-35 s/c=0.51 id=20% cov=84%
--------------MPELREDVVVDKVTSLLGLRKDDAAVL-----SLEETSLVVNVDSFESGIHlypFLPPRIAGRRAAVGSISDVLVKGAKPLGILVSLRVPSTADLGFLEEFYRGLLEAGTRFGARILGGDTDVSSTCY---LRVDVVAIG-VSRGKVLHRWGAKPGELVAITGRVGISSVLYALSSGGALScnpgNSLVEEYGWGQLPEPATWLGIKELLTSAIDNSDGLALSLYYLAESSGVGIVVEE--LPVHAVAKECLpreRLVDAVLYASGEDYNFIFTFPEEAEEEVRK--------TGATIIGRVTEGEGVFL----------------------
>UniRef50_B4WRX3(36-310:329) AIR synthase related protein, C-terminal domain n=1 Tax=Synechococcus sp. PCC 7335 RepID=B4WRX3_9SYNE  E=1e-35 s/c=0.55 id=19% cov=57%
----------------------------------------------------------------------------------------------------------EETQQIWAGMRAAATAYGVPIVGGHTNCHSEYSG----LAVAVLGRA--SQLITSFEASPGDTLmMVINMAGVYYGDYPFWNAATMAEPAMLRSHLS---KLTDLANANLCSAGKDISMGGLAGTLLMLCEASGCGALLDLNRVPRPVGVPWTK------WLTSFPSYGFLLSVPPNNVAAVKRLFASNQ--VVCQTVGEITPMTSVVLQ---------------------
>UniRef50_B9LT08(435-737:759) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Halobacteriaceae RepID=PURL_HALLT  E=3e-10 s/c=0.23 id=16% cov=55%
------------------------------------------------------------------------------------------------------------FKGIVDGLADACADLDAPVVGGNVSLYNDSVEGPIppTPTLALIGTRKgynaPPAALDADSAGDSELLLIGAGGADGGALggseyLAQAGGTDRFPTLPDTETKSLADRVASLAAVARHEstfATHDVSDGGLAVALAELVTDAAGADVTLPDRVAVFEETP----------------GRLVVqTTDPEAVAELAGEL-------PVLRLGEVTTDGALSL----------------------
>UniRef50_A4EBR4(18-362:367) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Bacteria RepID=A4EBR4_9ACTN  E=1e-34 s/c=0.43 id=24% cov=69%
--------------------------------------------------------------------------------VNDILASGAEPLFFLDYVAI-GHIEAEHMAKIIKGVADGCKLAGCALVGGEMAEHPGvMAPADYDLAGFTVGVVDRPKMLDPANVRPGDVILGLPSTGVHSNGYSLVRKVIGVdgikpgtpeaaakaeelsrpleelggaslaDALLTPTRIYVKPILELLRGGAPVHAIAHITGGGITENLNRALADdvdavvTRNGAEMGWDVPPVITYVSRQAELAPNEACKTFNMGvGLCLIVAPEDEAAVTEALVA--LGEKPFRVGECVEGSGKVV----------------------
>UniRef50_B0VGQ9(20-338:348) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Candidatus Cloacamonas acidaminovorans RepID=B0VGQ9_9BACT  E=2e-34 s/c=0.47 id=16% cov=30%
-----------------------------------------------------------------------IGQDLVNHCVNDILVQGAIPQFFLDYIGI-GKLEPAKVEKMIEGIIIACQQNSCVLIGGEMAEMPDLYKDeEFDLVGTIIGIVEQEQILPRPKIKPGDQLI---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q7UI59(40-355:359) Phosphoribosylformylglycinamidine cyclo-ligase n=6 Tax=Planctomycetaceae RepID=PUR5_RHOBA  E=2e-34 s/c=0.47 id=17% cov=82%
--------------------KLFARNYEEPVLVSGTDGVGTKLKIAQTMNQH-----------------ETVGIDLVAMCVNDLICTGAEPLFFLDYVAMGRD-DPARLERIVQGISDGCVDGDLALLGGETAIMPDMYGtDDYDLAGFAVGVVERKRLVDGHLIAPGDVVLGLQASGLHSNGFSLVRKIIadhghqwsDVIDELNQDTKTPETLAQVCLRPTKIyvsairsiqshyrvkqvlHGIAHITGGGIEENLDRILPP-GVNAEIDPNAWTPNPIFQWLQQTGDVatsEMRRVFNMGIGMAVVVNEYYAASVAS-QVAKAGIECSPIGRIVEGSSKVV----------------------
>UniRef50_C9M8L2(13-330:332) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Synergistaceae RepID=C9M8L2_9BACT  E=6e-34 s/c=0.46 id=20% cov=70%
-----------------------------------------------------------------------IGQDLVAMNVNDLVTGGARPLFFLDYIAC-GALNEPVFAPVVESVARACASCGCALLGGETAEMPGVYGPQtFDLAGFAVGVVDERDVIDGSSVQEGDLLVGLHSSGVHSNGYTLVREalaqsiakgdlsrpgpvpGETLGQSLMKPTRLYVNQALSAARTGAVKAMAHITGGGMAGNVNRVLPAGLVCdVDFSSWKRPAVFDLIASCGVAEDEMRRVFNLGiGFVMITSPDSLGRLTDALKAA--GENPQVIGRVV-----------------------------
>UniRef50_A0QAT1(444-732:765) Phosphoribosylformylglycinamidine synthase 2 n=34 Tax=Bacteria RepID=PURL_MYCA1  E=6e-25 s/c=0.40 id=23% cov=70%
--------------SRAFITEQYDRYVrGNTVLAEHADGGVLR--VDETTGRGIAVSTDASGRYTM-LDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQFaqaVRGLADGCVALGIPVTGGNVSFYNQTGSAAILPTpvVGVLGVLDDvsRRLPTALGAEPGETLMLLGETRDEFDGSVWAQVTADHLGGLPPkvDLAREKLLAEVLRAAsrdGLVSAAHDLSEGGLAQAVVEaaLAGETGCRIVLPEDADP--------------------------------------------------------------------------------------
>UniRef50_Q46E56(20-329:333) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=Euryarchaeota RepID=PUR5_METBF  E=2e-33 s/c=0.47 id=18% cov=47%
-----------------LIEKL---SYVRKGMGAPLTGIGHYAGLLDFGEYALALTTDGVGSKVLIAnemqRWNTVGIDCIAMNVNDLLAIGAEPVAFVDYLALEKH-EEGFAAQIGEGLVKGAEISRMSIVGGETATLPE-IIKGFDLAGTCLGIVRKDEIVEGEKVRVGDVIVGVPSTGVH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B4U7I6(42-335:336) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Hydrogenobaculum sp. Y04AAS1 RepID=B4U7I6_HYDS0  E=2e-33 s/c=0.49 id=14% cov=27%
--------------------------------------------------------------------------------VNDIITTGSKPIAFLDYIAI-GMIEGSTINPLIEGIITGCEEANTPLVGGETAEMPSFYKDGEYdLAGFCIGICKKDEIVTGQDVKENDIII---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B8HPV7(54-363:367) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Cyanothece sp. PCC 7425 RepID=PUR5_CYAP4  E=2e-33 s/c=0.47 id=20% cov=69%
--------------------------------------------------------------------------------VNDVLTCGAEPLFFLDYLA-TGHLEPEALTDVIAGIAQGCQQAGCALLGGETAEMPGfYPVGEYDLAGFCVGIVEKAEMLNGSQVRMGDRAIGLASSGVHSNGYSLVRKIVDefigpaareqseagatealvspwsitpwaeredlppvdrqqsLGAALLTPTQIYVKPVLAAQRSGLtLHGMAHITGGGLPENLPRCLGE-GQSVQLDPQSWPAPPIFDWIASTGSVptaAMFDTFNMGiGFVLIVPPDEVESALRWFNTQQC--PAYGIGEVVAGAGEVL----------------------
>UniRef50_Q97CD7(15-327:338) Phosphoribosylformylglycinamidine cyclo-ligase n=4 Tax=Thermoplasmatales RepID=PUR5_THEVO  E=3e-33 s/c=0.46 id=20% cov=86%
-----------GEFVSSFIRQLKFHREDFKNIGY----IGGFTSLIDMGNFALSFNNDGVGTKTMIAEQANkydtLGIDCVAMNVNDAITVGSEPIAMVDYLAV-RDLNEDIAKQLGNGFNVGAQIANISIVGGETAVVPE-IVNHIDVSGAVIGIVQKNQIITGANIKEGDVIIGLGSSGLHSNGFTTVRkiisdneinlfdnfpgESKKTYEVLLEPTRIYVREILDVMGIIQIKGMANITGGGF----KNITRMKDMKYVIDDPMEPQNVFVR-LMELGNLNykqMYEIFNMGtGFVVVIGEDDKIDFINTLKNR---VPLKVIGHVENGTGV------------------------
>UniRef50_D1N3I6(6-286:297) Thiamine-monophosphate kinase n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N3I6_9BACT  E=3e-33 s/c=0.52 id=21% cov=46%
--------------------------------------------------------------------------------LSDIAAMGGTPKWALLALAV-NGHSEEWLLEFCRGAHEAGAAFGVPVVGGDLAELENKGEAG---SLTILGEIAASEVILRSGARPGDRLYVTGEFGNSLTSG----HHLNFTPRLREG--------RLLARKHFATAMLDVSDGLLLDAV-RLACASQVDLVMNPGKVPLR------------------------------------------------------------------------------------
>UniRef50_O29525(10-278:296) Probable thiamine-monophosphate kinase n=1 Tax=Archaeoglobus fulgidus RepID=THIL_ARCFU  E=6e-33 s/c=0.54 id=25% cov=33%
----------------ELI-KLVERLFGDE--DVITPAGKHDAAYVKIGNRLIVLTCDTVNEKSDFPPymlPEEMGWMAIAVTLSDVAACGARPLYFLSSISL---KSIEFFEDILLGIKRCADRFGVKVVGGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A5FPS3(37-346:354) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=Dehalococcoides RepID=A5FPS3_DEHSB  E=6e-33 s/c=0.46 id=19% cov=69%
-----------------------------------------------------------------------IGIDIVNHSVNDILTSGAEPIFFLDYIAM-GKLSPGKITEIVKGLSTACLEAGCALIGGETAEMPGlYHGEDYDLAGFIVGVVEKENMLINRGIKPGDIILGLASNGLHTNGYSLARKVLGESRESLDKYYPElgQTAGEAMLvphrsylkeikpNLLLIKGLAHITGGGLTDNVPRTLPE-DVSARFETKNWEIPPLFQLIQKTGGIDheeMFHVFNMGiGMVIIAGTEEAGLIMKNL------PEAKIIGEIIARQ--------------------------
>UniRef50_D1JHF1(36-348:362) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=environmental samples RepID=D1JHF1_9ARCH  E=7e-33 s/c=0.46 id=20% cov=68%
--------------------------------------------------------------------------------VNDILCVGAEPISLVDYIALCEP-DPELLEEIGKGLLKGAEIANITISGGEIAIVKDMVKGvrknrEFDLVGTAVGTVSLDKVIVGANIQEKDVIIGLSSSGIHSNGLSLARHiflktgaidehfdvlEKTIGAELLEPTHIYVPEIMEMINSNlDIKALMHITGDGFL-NLTRVKSEVGFVIEYLPETPPIFTLLQKRGNVTDEEMFRVYNMGiGFCVILPEQEAEVAIEIASRHK--VDAFRLGYVVKDP--------------------------
>UniRef50_C7RG06(21-326:337) Selenide, water dikinase n=2 Tax=Anaerococcus RepID=C7RG06_ANAPD   E=9e-33 s/c=0.47 id=21% cov=60%
-----------------------------------DDAAIID----IDGETCVIQTLDFFptmVEDPYLF-----GQIAAANALSDVYAMGGEVISALNIVTFPLEEDFAILKEILRGGNDKVSEAKASLTGGH-SIHDKTIKYGLSVT----GKVKKKEIRENNTPKDGDVILLTKKIG-TGLVTANFAQGLVSDEDFEACtrqMATLNKYARDIFVKYQIHAATDITGFGLLGHLSEMA-GNDFTIILESAKVPV-------------------------------------------------------------------------------------
>UniRef50_C8QB92(42-298:319) AIR synthase related protein n=3 Tax=Enterobacteriaceae RepID=C8QB92_9ENTR  E=9e-33 s/c=0.56 id=20% cov=49%
--------------------------------------------------------------------------------LSDIAAMGGRPLAVVNALW---DDTLPHAEQILQGMAAASRAYQVPIVGGHTNL----RSDQPQLAVAILG--ETRAPLSSFAVQSGQTLMVAINLrGRWHPPGYNWDAATEAAPAALRQAWSLLP---ELAEAGLIRAAKDISQAGLAGTLVMMLESCDLGAELALEQIPIPDDV---------------------------------------------------------------------------------
>UniRef50_Q55946(33-310:322) Uncharacterized protein sll0787 n=15 Tax=Bacteria RepID=Y787_SYNY3   E=2e-32 s/c=0.51 id=15% cov=64%
--------------------------------------------------------------------------------VSDIYAMGGRPIAVVDALW---SKSSDQAQQIWAGMQAASARFNVPIVGGHTNTHSGYDA----LGVAILGRAKS--LITSFDAQVGDRLILVSN----FQGKPRPNAPYCWDAATMAETETLqkhWDLLPYLAENKLCDAGKDVSMGGIIGTALMLLETSKCGAILDLDAISCPAGLDF------RQWLLSFPSYGFLLSVRPQFVKTVKACFQAEGLIAEA--IATIQPGHNLTLK---------------------
>UniRef50_Q3B0X6(28-318:331) Thiamine-monophosphate kinase n=11 Tax=Synechococcus RepID=Q3B0X6_SYNS9  E=2e-32 s/c=0.48 id=22% cov=52%
----------------------------------------------------------------------DVGWRAVAANLSDLAASGAISVdGITVALVAPGETPWSWVEGVYTGLRAALDAYGGVILGGDCSKGSQR-----LLSITALGRLGPLR-LHRGDAKPGDILVTSGPHGLSRLGLAILQndkalHGIDLPDALRtaavNQHQRPIPRLAALQELLNCKpeslpwrAGGTDSSDGLLAAIQGLCSSSECGAVLDEKLLP--------------------------------------------------------------------------------------
>UniRef50_A7B5B2(4-332:345) Putative uncharacterized protein n=2 Tax=Clostridiales RepID=A7B5B2_RUMGN  E=3e-32 s/c=0.43 id=18% cov=93%
-----------GNVSQTVLKRSVLKQLHTKRKEILTDLSVEEmcTAVQIRDTEDVVFAS-AVVSG----NSKNIGVYAIMRAVLDLETRGASAIGVSVQVILPTYAYESRLKEMFRCMEERCASWGIAITCAKAETSPAVSQS--VVSVTAAGSVEKGQLRTLAQAEPNQEIVLCGSIAAEGVLRIFDEKREELSKRFVPAFMRQIQGIESELEVFHalrsvkqentpkgeplVTAMQQIGSGGILASLWELTEAANVGMQIEMSRISIRQECVEVCEYYHLNPYQMTSAGTVLMVTRDGNA--LVRCL--EESGARASVLGVTTADHAKVITSGDEV-RYLDRPAPDELMR--
>UniRef50_Q055K0(3-280:299) Thiamine monophosphate kinase n=4 Tax=Leptospira RepID=Q055K0_LEPBL   E=3e-32 s/c=0.51 id=18% cov=64%
-------------------ESEIIRVLYPPGAAQTDDCYLDEEGRI--------FTTDTICEGTHFRTEWsgpkEIARKLVEVNVSDIAAGGGVPTKAFLNLGLSSQYSkEEWIRPFSSSLQNALSFYNIELCGGDTYLSPS-----LNLTLTLIGVT--ARPWKRSGGKNGDFLYLTGSVGLSLLGYKLLNKSLDVPEPLRnlalEKHLTPKARLnvsKELSKRFPVSCCMDLTD-GLLQDLPKLAYSSKLGLKIDLEKIP--------------------------------------------------------------------------------------
>UniRef50_Q2S2H8(12-332:337) Phosphoribosylformylglycinamidine cyclo-ligase n=10 Tax=Bacteroidetes/Chlorobi group RepID=Q2S2H8_SALRD  E=3e-32 s/c=0.44 id=24% cov=28%
----------------------------------------------------------------------------VNHCVTDVAVCGARPLYFLDYYGV-GTLEPDTAEAVVEGFATACDDNDCALVGGEIAEMPDVYGEGdFDLVGTVVGLVDKGTIVTGDEVRPGDVLL---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6QAK6(62-372:740) Phosphoribosylformylglycinamidine synthase 2 n=33 Tax=Epsilonproteobacteria RepID=PURL_SULNB  E=3e-32 s/c=0.45 id=20% cov=29%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLTSSAFEMAGKTGAGLIMHLDKVPAREE-----GMTPYDFMLSESQERMLICAKKGREQEIIDIFEKWEL--DVAVIGEVTDTERMEL--FWYGDKVCDMPIA-------
>UniRef50_A6DQ43(5-284:299) Thiamin-monophosphate kinase n=1 Tax=Lentisphaera araneosa HTCC2155 RepID=A6DQ43_9BACT  E=4e-32 s/c=0.50 id=15% cov=63%
--------------------------------------------------------------------------------LSDIAAMGGIPRYAVLSCNVNSACSEQWLKDFHHGLLKCGEEFSVHLIGGDLASSPGPNAFSLTITG------ESAKPIQRCGAEDGDLLFSTGEFGLSFPS---------------EHHLHFTPRVEEGKFLSSYAKAMIDVTDGLLLDSQRLLKASANTLDLTFLTQEIPARNFLAKDASLKESFCDGEDYELIFAVGPKRVKELIE---RWPFSTKLSKIGEFKKGTGKILD---------------------
>UniRef50_C5BI56(61-319:338) AIR synthase related protein domain protein n=1 Tax=Teredinibacter turnerae T7901 RepID=C5BI56_TERTT  E=4e-31 s/c=0.53 id=21% cov=31%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WAVPAELAEAGLAVAAKDISNGGVLGTLIMMLELTGCGATLDLSAIPRPPG-------DLLRWLRAFQSYGFLLAVEPDKVSGLLNYFRA--SHLTCSPVGEITDSGTIVLD---------------------
>UniRef50_Q9X0X3(54-322:603) Phosphoribosylformylglycinamidine synthase 2 n=9 Tax=Thermotogaceae RepID=PURL_THEMA  E=8e-31 s/c=0.51 id=20% cov=66%
----------------------------------------------------------------------------VGGIIRDVLAMGARPTAIFDSLHMSR-----IIDGIIEGIADYGNSIGVPTVGGELRISSLYAHNPL-VNVLAAGVVRNDMLVDSKASRPGQVIVIfggaTGRDGIHGASFASEDLTGDKATKLsiqVGDPFAEKMLIEaflEMVEEGLVEGAQDLGAGGVLSATSELVAKGNLGAIVHLDRVPLREPDMEPWEI-----LISESQERMAVVTSPQKASRILEIARKHLLFGD--VVAEVIEEP--------------------------
>UniRef50_Q0BZA9(405-728:728) Pyridine nucleotide-disulphide oxidoreductase / selenide, water dikinase n=35 Tax=Rhodobacterales RepID=Q0BZA9_HYPNA  E=2e-30 s/c=0.42 id=24% cov=80%
------------------------ALHADTITGAGDDAAVLRSGARLQ-----VISTDhlrAFVDDPYL-----MARIAAVHALGDVCAMGAAPQSALLSLIIPrmsDPMQKATVAEVVAAVSDVLRAAGADLVGGHTSM-----GRELTIGLTVTGLLDGP-AIGLTGARPGDAILLTKPLGTGvilAAEMRGLARGKDVEHALASMQRPLAAASKILAPAA--HAMTDVTGFGLAGHLMSILEASDVSARIALPDLPVLPGAEQLSaqgirsslwqsnasleprisrpaspiSDLIYDPQTA---GGLLAVVPSQSVTGLLSAFQAE--GEPAFVIGRIEEGPPRIL----------------------
>UniRef50_C0VYS5(27-367:381) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Actinomyces coleocanis DSM 15436 RepID=C0VYS5_9ACTO  E=3e-30 s/c=0.40 id=24% cov=87%
-----------GDRTVELMKAAVNASHNNTVLAGAGGFAGLIDASALVGMKRplLASSTDGVGTKVAIAQAMDihdtIGQDLVGMVVDDLVVMGAKPLLMTDYIATGKVVPEK-IADIVRGVAQACAMVDCPLIGGETAEHPGlMAEDEYDIAGAATGVVDEPNLLGAHRVQAGDVLIGMAASGLHSNGYSLVRRiiadagwewdrhvdefGRTLGEEVLEPTRLYTRDCLALIDAlpGQVHALSHITGGGLGANISRVIPQ-GLTAIVERDSWTIPP-VFDVMRRLGAVPWAALEETlnlgvGMVAVVSAEGAAQAVSVLAAA--GMSAWVLGRVV-----------------------------
>UniRef50_D0LC24(41-328:361) Thiamine-monophosphate kinase n=1 Tax=Gordonia bronchialis DSM 43247 RepID=D0LC24_GORB4  E=2e-29 s/c=0.46 id=23% cov=57%
----------------------------------------------------------------------DVGARAIVQSAADIAAMGGRTTGVVVSIAAPPSTPVGTLLDLNAGMVDATHLLGARLLGGDLV-----AAGQVVVSVTAVGAMDGRAPVALGGARPGDVLAVSGRLGACAAGLAVLssdrPADVERWPDLVAAHRVPTPDLAqgPIAAARGAHAMTDISD-GLVEELITMSQASGTQMSVDSSRVPRSDRVTALAAEWGVD-----------------------------------------------------------------------
>UniRef50_C3XH11(492-758:798) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XH11_9HELI  E=3e-16 s/c=0.33 id=17% cov=52%
-------------------------------------------------------------------------KIAVAQAGRDVALSGAKPLAITDCLNFGSPENPEVMWQFretCEGIKEACKALQTPVVSGNVSLYNQTNDEAIYPTPSIvsVGLLEDsNKAIGSHFVSKDSYICMLGvmdnSLQLSGSilqkVIGAKNSGILHDINLESELK-LWEILNQSIANEYILSAKDIAQGGLAITLCKMAILGKTSVEVLTDKI---------------------------------------------------------------------------------------
>UniRef50_A4E732(2-277:278) Putative uncharacterized protein n=1 Tax=Collinsella aerofaciens ATCC 25986 RepID=A4E732_9ACTN  E=7e-29 s/c=0.47 id=20% cov=69%
-----------------------------------------------------------------------FGQIAAANSLSDIYAMGGRPSHAMNLLCIPSCLGIEVAGQILAGGADKCVEAGCSIAGGHTIND-----DEPKYGLSVSGFVALDRMLANSGARVGDALLLTKAVGSGiiTTAIKGELIEQDEAAAVFDSMRTLNEAPIRLAEGLELHGCTDITGFGLIGHACEMAEGSGVQVELASGAVPLFDQVLDMARLGiipagsyrnqdffgprvaadeDLEPgmldalYDPQTSGGLLIAAPARDVDELARRLDAE--GRIAAVVGRVCE----------------------------
>UniRef50_B5JNY9(18-301:326) Putative uncharacterized protein n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JNY9_9BACT  E=8e-29 s/c=0.46 id=18% cov=34%
---------------SKLIEQMqvwLGEANPAPPNGIGDDCAV---APTPTPNTKQLVTADPVIYGKHFNDshsPEQAASKLARRNLSDIAAMGGRPTHAIICLALSKNVSISWIKRFYQTLAHEANTHQFKIIGGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q4JAU5(31-280:294) Thiamine-monophosphate kinase n=2 Tax=Sulfolobus RepID=Q4JAU5_SULAC   E=1e-28 s/c=0.52 id=16% cov=70%
----------------------------------------------------------------------DIGWRSVIGVISDILSKGGSPKFFLASLGLNKN-RLKEIENILKGISDAINYYKGSYVGGDTNSSDNNGWIDI------VGIGEAVCYKSVDNIKRGDKVIITSPIGYNSIIFISYVNNWKISIPLKYKLKYKHPIVNPHLqdifsqNCDNIHYSLDISD-GLIVSLYNLVERSKLGIEI--TKMPVSEEVLNIANNYKIRLLdllkFSGEEYESIFVVDKDSYHKIINQMKL--LGLNPVVFGEISDRQGVYFNGE-------------------
>UniRef50_Q4JUX8(24-286:332) Thiamin-monophosphate kinase n=4 Tax=Corynebacterium RepID=Q4JUX8_CORJK  E=1e-28 s/c=0.49 id=20% cov=54%
----------------------------------------------------------------------------------DIQAMGARPTAILMAIATPGDLPLQTVADIARGIDEAASPWAAELVGGDVVTS-----KDLVISITALGEISgPAAALTLDGAGVGQRIIASGPIGYSAAGLAVLRHYGSRKAIPANDPilneladWHCAPRLEPGRgsvARATGASAMTDNSDGLIVDLCAIAERSGVCLDLDGAALVPDEKLRHAAQMTGKNPL---------------------------------------------------------------------
>UniRef50_C7NKL2(37-285:357) Selenophosphate synthase n=13 Tax=Actinomycetales RepID=C7NKL2_KYTSD  E=1e-28 s/c=0.52 id=18% cov=62%
-----------------------------VGLDDGDDAAVVQVA----PGVASVSTADFFT--PVVDDPRTWGRIAAANALSDVYAMGGTPVMAINLVGWPRaALPMELLTEVLAGGLEIATQAGCPVIGGHSIDSP-----EPIYGMAVTGTADPDRLLRNDAAEPGLPISLTKPVGLGILNNHHKTTGALHPHAIEVMTQ-LNAAASRAALQAGVRAATDVTGFGLLGHLFKMCRASAVAACIDAGAVP--------------------------------------------------------------------------------------
>UniRef50_C6HZI7(53-350:741) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Leptospirillum ferrodiazotrophum RepID=C6HZI7_9BACT  E=2e-28 s/c=0.43 id=21% cov=67%
----------------------------------------------------------------------------VGGILRDIFAMGARPIALTNSLVMGSlrqPRQMTLFRRVVAGIGAYGNSIGVPTVGGEIWFDERYAKN-ILVNAFAVGVVPDDAIM--SAIPPDKPLLAvylgnkTGRDGVSGAAMAS-RSFSGEEADLRPQVQVADPFVGKkvmeatlsIIRQGLAGAIQDMGAAGLTSSSVEMADKAGKGIEIDVLKVPLRDPSMEPWEI-----LLSESQERMLLLVEEQNVGAILDL--AHESQVAAAVIGQMIAEP--------------------------
>UniRef50_Q72IH7(412-712:725) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Bacteria RepID=PURL_THET2  E=7e-22 s/c=0.36 id=21% cov=69%
-----------------------------------------------------------------------------------VSVVGAKPLAYTDGLNLGSPETPEgyhELAETIAGLKEASEALGVPVVSGNVSLYNESGGKRIPPTAMvgVVGVLEVDKRAEMGFRRPGEVLLLIgeerGELGASEVLYLLTGKEFGHPPRLdLGREKAVQEAIRDLIQRGLTRTAHDVAEGGLLLALAEMTFPYGVGATVEV-------------REEGLEALFGEAPSRVLFTVEKTRLQE--ATLLLEERGLPYRVLGE-TGGKSLTVLTPGG---VLEWSLEELL----
>UniRef50_Q9VKY8(15-353:370) Selenide, water dikinase 2 n=9 Tax=Drosophila RepID=SPS2_DROME   E=1e-27 s/c=0.37 id=17% cov=30%
------------------------------------------------------------------------GRIALANVLSDVYAVGVT-QFDTVEMIVSTSTSFSEKERdvviglVMKGFQNSLKANGyrnTPLIIRQLKINP-----WCIIGGIATSVCRSEEIILPSNAQPGDVLVLTKPLG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7XXZ8(34-317:347) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Lactobacillus coleohominis 101-4-CHN RepID=C7XXZ8_9LACO  E=1e-27 s/c=0.44 id=19% cov=71%
----------------------------------------------------LAMTTDGNGRFVYLDPEIG-GQMAVTEAYLNIVASGAEPLAITDCLNYGDPNDPEIFWELhhsIEGMATACRIFDTPVISGNVSLYNENNGRSIYPTpmVGMVGLIKNlDHVIPSFATHAGDDVYLIGQTGNDYAGSELQKLMTGQISGTLSkvnlqRIQEYCGRLHSEMVAGHVTAAHDVSEGGLGVAFAEMLFAGETGMNLDL-------------RDLTATQLFSETAGRMIVTVPSAFKTEFEDAM-----GNDAQWVGTVTNTH--------------------------
>UniRef50_A0B5C7(57-391:768) Phosphoribosylformylglycinamidine synthase 2 n=1 Tax=Methanosaeta thermophila PT RepID=PURL_METTP  E=3e-27 s/c=0.37 id=17% cov=90%
------------KSSRAVLREFLPTEGPNVVLGPVEDAGIVS----IDDEWCVVISHESHNHPSQILPNEGAAT-GIGGIVRDVNCMGARVVATADPLRFGDPYGREssrvrwVAEGVVDGIWQYGNALGVPVIAGDVVFSRCFDYNCL-VNVVAIGVVRRDEIIRsrappGSGEKGYDVILIgkpTDSSGLGGVIFASDTLREEEEEANRGAVQIPDPFLknvlfkanedlfRLVREKGVEIGFKDLGGGGLTCASSEMGAAGGYGMEIDLDRLHV------AGEFPPEVLCIAETQERFLIIAPRELRERILKIynedwdLPNVYEGARASVIGRVTTHDRYIVRHR--GEEVVNVPIK-------
>UniRef50_A8A992(18-318:319) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8A992_IGNH4  E=4e-26 s/c=0.40 id=23% cov=66%
---------------------------------------------------------------------------------NDVACEGFRVFAYVDYLAVERGDPV-LAREVAEGMSKAAEALGAVLAGGETAIMPDV-VKGYDVSCTVLGVREA----RPQPPRPGDAVIAVASNGPHANGYTLIRRliqaGLLDPEPLLDFLLAPvanyhNPLLRAMKE-GKAKWGAHVTGGAFYKVHSRLPKGLGV----RLEAWEVPEGFVKIVEAAGMsaeEAYKTFNMGvGMLVVGSEEAVEAF------EREGLKAWKAGEVVEGPT-EIETPWG-----------------
>UniRef50_A4A8V3(412-737:743) Selenide,water dikinase n=3 Tax=unclassified Gammaproteobacteria RepID=A4A8V3_9GAMM  E=4e-25 s/c=0.36 id=21% cov=67%
-----------------------------------------------------------------------MGRIAAQHALSDLYAVGAKPHSAQALVTLPfaaPALLRRDLLMVLQGALSVFDEVGCTLDGGHSMQGPELQLGFAVNGVLAAG----DAPLPKRGAQPGDTLLLSKTLGSGALFAAHMQGladGRHVDDALHALEQ-GNGAAAKIARDYQARAVTDVTGFGLAGHLLEMlgdtlaadielgklkitdgaldAMTAGVFSTLHEPnrqaivaRWAPPEDLPLLAELL-FDPQTS---GGLLMAMPPEKAAQACEALHAQA--VEAELIGT-------------------------------
>UniRef50_B5CL78(81-346:352) Putative uncharacterized protein n=1 Tax=Ruminococcus lactaris ATCC 29176 RepID=B5CL78_9FIRM  E=2e-24 s/c=0.44 id=20% cov=68%
--------------------------------------------------------------------------------------------------ILPEQMQEEDVKHLTDTVGELCKKMNLEIC--QIQVETSSFVTQMVVTATAVGEKKSTAIREQEMTVAGEELLLCGYAGLEGTLRILDESEEELGTRFVPVFLEKAKLLREklvlpdqiLSVKEQVSDIRQIGSGGILAALWELGEELQTGFDIDFSKIALKQETVEICEFYQLNPYLMTSAGSFLLVT--GQSEEVIACL--AEQGVSAVRLGCMKDQNARVIKNG-EETRYLDRPAADELAR--
>UniRef50_A6BF49(73-314:338) Putative uncharacterized protein n=1 Tax=Dorea longicatena DSM 13814 RepID=A6BF49_9FIRM  E=2e-24 s/c=0.48 id=19% cov=55%
----------------------------------------------------------------------------------------------------------------------------------------------IAVTVTGIAKAPKEEAWNRETARACRDIVFVGHAGMDGMLRITEEKEQELKTRFAPVFmkqiklygqQIFAPKEIEAAKAGGAFVVRQVADGGILAALWNLALELNQGLDLDMKKISILQETIEVCEHFRLNPYQMISTGSFLAVT--DNGEVLADAL--NNQGITAAVIGHTTDNNDKILRNG-EEMRYIDRPAPD------
>UniRef50_B7G902(415-759:791) Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1 RepID=B7G902_PHATR  E=2e-24 s/c=0.33 id=19% cov=68%
-----------------------------------------------------------------------FGKIVAVHALSDIHAMGATPQtAMTLAvapFAADEEVTESTLLHLLSGVSDILQDENVQLVGGHTC-----EGLELACGLSVQGYTDNPKLLLRKqGGAIGDKIVLTKPIGTGALFAADMRARCKgsyMSEALDSMIHSNCHASQVAMRAKGIRSCTDVTGFGLIGHLLEMLMANETVKELDSigavvnigDIDFLRGGLEASANGifstlqsqngrnrraivnhteaaekypvkypLLFDPQTA---GGLMFFVDALSASEFLAELRAAD--VNAHIVGELV-----------------------------
>UniRef50_A6W9Q5(218-464:479) GCN5-related N-acetyltransferase n=5 Tax=Actinomycetales RepID=A6W9Q5_KINRD  E=5e-24 s/c=0.46 id=22% cov=63%
--------------------------------------------------------------------------------LNDLAAMGATPVGMLDALAA---RDAHQAQRIVSGLRAAATAWGVPVLGGHTQL-----GVPAALSVTALGRT--GSPVPAGGGRAGDEVRLTADLGGGWRPGYRGAQWDSTSTRRGEDLRAMGSFVARSRPD----AAKDVSMAGLVGTLGMLAEASGTGAEIDVAAVP-RPGAASVG-----DWFTCFPGFAMVTASRPGWEPQ-------HAGPATSAACGRLVAGEGVGLRWPDG-----------------
>UniRef50_Q5WW17(514-766:780) Phosphoribosylformylglycinamidine synthase II (FGAM synthase II) n=5 Tax=Legionella RepID=Q5WW17_LEGPL  E=1e-17 s/c=0.37 id=20% cov=29%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNAAHDVSEGGVAVALAEMSFKNSLGVAV------------QINGELSTDKLLFGETGGFILEIDKQHKAAFDKLV--TQYQVPYMVIGHTTEQPVLQMNS------VINLPVEE------
>UniRef50_B9XQX7(4-318:342) Phosphoribosylformylglycinamidine synthase n=1 Tax=bacterium Ellin514 RepID=B9XQX7_9BACT  E=1e-23 s/c=0.36 id=20% cov=68%
-----------------------------------------------------------------------------------LACSGAVPLGSTDNLNYGNPHNQEIFWQLkesVRGLAEACRAFNAPVTGGNVSLYNQNPNGPIdpTPTVAMVGLVEKPEHITTQWFKdEGNAIILLGDIvdtsdpllGLGGSAYLQRIHGKKTGTPPRcnlDKEKELHLGLRSLIYSGVVKSAHDCSDGGLAVALAESC----ISQQVARETPRLIGADIDLSSITGtrLDAlLFGETQSRVIISVDKHQAGKVLG--QAKILGIPAIKIGSV-GGTALQIKTS-------------------
>UniRef50_C3XNX3(5-289:293) Thiamine monophosphate kinase n=1 Tax=Helicobacter winghamensis ATCC BAA-430 RepID=C3XNX3_9HELI  E=4e-23 s/c=0.39 id=18% cov=32%
-------------------EKAFIRALIQSGATEG---IGDDGVLIARDCAGYVVASDAFFEDVHFKRAWGsleaIVEKCFAVNLSDIYAMNAIPSFCLLTLALPNGF--KEVGRLANVIGKCALKHRIKIIGGDT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C8PEU3(4-160:414) Thiamine-monophosphate kinase n=1 Tax=Campylobacter gracilis RM3268 RepID=C8PEU3_9PROT  E=4e-23 s/c=0.71 id=24% cov=42%
-------------------ERYIFEKFRSKL--NGDDCAVI---------GERAYCKDLFVEGVHFRRGWlslrEIGAKAMLVNISDMIATNARAKYALLGLALPREIGTREIDELCAGVSETAREWGIRIIGGDTI-----GSDRIALSVSLIGKCK--RPVFRSGARVGDLIAHTGELG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9K966(40-312:314) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Thermotoga neapolitana DSM 4359 RepID=B9K966_THENN  E=4e-23 s/c=0.41 id=18% cov=26%
---------------------------------------------------------------------------------NDLVCVGARPVAFLDYLGVERISEEH--EQFITELVDVLENVGVKLVGGETAEMPDVYHGDWDAVGFAVGVLERKIPV--DTIKEGDIIV---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A8M9Z8(52-301:315) Thiamine monophosphate kinase-like protein n=1 Tax=Caldivirga maquilingensis IC-167 RepID=A8M9Z8_CALMQ  E=1e-22 s/c=0.44 id=25% cov=65%
------------------------------------------------------------------------------GAASDLLVKFAKPIALVTSLTLRGDHTESELEELIKGINDAAKAIGASYIGGDL-----NEGDDDVLDVALIGIAGKPI---GRVPRLGDVLVTIPEFGFTGLIFKLWYSGLLsnyindsivvKGIELTRRPKPWIPSGELGNRINCVNASMDSSDG-----LGRVLYEMGKGVRIRVYSLPVNKDVESTCRRYGLSveevVFNGGEEYLPVLAVKPE----CLDYFKALGFVDFA----KVEEGNGVYLDSR-------------------
>UniRef50_B1X4P8(421-791:791) Putative uncharacterized protein n=1 Tax=Paulinella chromatophora RepID=B1X4P8_PAUCH  E=3e-21 s/c=0.28 id=20% cov=69%
------------------------------------------------------------------------GRLTTLHACSDLWACGADVRSLQALVTLPKNnssLQEELLFQTLEGIISVINSTGGKLIGGHTLENRDNSlanhkiltnnhltpiSEDLQVSLIINGQCPKDCFWPKGGFKHEDSLILSHPIGTGalfAAAMVNAAKPDWIDSAIEGMQQNQSSIVE-ILAHYSVNAATDITGFGLLGHLGEMLKASNpadlwerkiseLVVNLDYLSIQTFPGVNELikcgftstLALPNRIYWQLIEQGMikislpnsvsidsflevlidpqtcgpILISLPKTEAQHALVDLHANGF-KNAKIIGKV------------------------------
>UniRef50_B5DRN0(70-392:395) GA28664 n=1 Tax=Drosophila pseudoobscura pseudoobscura RepID=B5DRN0_DROPS  E=5e-21 s/c=0.32 id=21% cov=74%
-----------------------------------------------------------------------MGKIACAKVLNNLYAMGVsDCDNLTMMLGVSNRMTMQErdvvLPLILSGFRFRASDVGAPITGVQTIANPWCFLGGEASSVCQMdGFIEPGYAID------GDVLVLTKPLGtqlalnayqhITGKGTRCKRMQLKLtDEEVQQTHRqaikcmsRLNRVAAGLMFKHNAHGATHIGELGLLGHAQHLASLQRNAVSFSIYNLPLIKNVEKLARsivDANNKLLQGrapEHSGGLFICMPQEQATAFCKDLKRLD-GHSAWIIGLVEKGNR--------TARLVQSPRAIPV----
>UniRef50_D2R8C5(650-961:981) Phosphoribosylformylglycinamidine synthase II n=6 Tax=Planctomycetaceae RepID=D2R8C5_9PLAN  E=3e-14 s/c=0.26 id=25% cov=30%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRACHDISEGGLAVAIAEMAFAGDLGAHVRLADVPLDDTITDPA-LRMATALYSESCTRFVLEVPADKQGSLEELL----AGVPFAALGRVMPAKRVSFAAPGGA----------------
>UniRef50_UPI0001C31B45(8-305:326) thiamine-monophosphate kinase n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C31B45  E=2e-20 s/c=0.34 id=22% cov=71%
----------------EALSEILADEHDRVVRWIGDDAAVVRAR------PYAVTSVDTMVDGVHFrfdggdgtASLADVGHRALAGALSDVAAMGAEAGEAYLALVLPPGLDDAALRELFAAAQQLAAATGTTIAGGDLARGP-----ALVASVTVVGWADAEhELIGRDGARPGDLVGVTGALGGSGAGLELLEGRVgparldpDVARALIRRHLRPQPRIAEGRALAAAGARAMIdISDGIATDAGHIARRSGGRLVLALDRLPLADGVAEVAAALG-------------------------------------------------------------------------
>UniRef50_Q65RJ7(236-606:1297) Phosphoribosylformylglycinamidine synthase n=45 Tax=Bacteria RepID=PUR4_MANSM  E=5e-20 s/c=0.27 id=19% cov=76%
------------------------------------------------------------------FPGAATGS---GGEIRDEGAtgRGAKPKAGLVGFSVSnlviPGFEQPWENELSKpsrissaldimiegplGGAAFNNEFGRPALLGYFRTYEEkvnsfageevrGYHKPIMLAG-GIGNIRAEH-VQKGEIPVGAKLIVLGGpamnIGLGGGAASSMTSGKSKEdldfasvqrdnPEMERRCQEVIDRCWQMGEGNPIAFIHDVGAGGLSNAMPELVHDGGRGGKFELRNILCDER-----GMSPLEIWCNESQERYVLAVAPENLAVFEELCQRERA--PYAIIGEATEEEHLTLHDNHFDNNPIDLPMSLLL----
>UniRef50_C0F9P1(286-601:1035) Phosphoribosylformylglycinamidine synthase II domain protein n=1 Tax=Wolbachia endosymbiont of Muscidifurax uniraptor RepID=C0F9P1_9RICK  E=4e-19 s/c=0.31 id=20% cov=48%
-----------------------------------------------------------------------------------------------------------------------------------------------------VGIIPRNInnaPSHIKGPKNGDKIVIIGGrvgrDGIHGATFSSEALSGNSPSTIVQigdpiTQKKLSNAALEARDLDLYNAITDNGAGGLSSSIGEMGKDG---FEVDLSKVLLKNDGMAPWEI-----WISESQERMTLAVPEENLPMFKQIMKKHD--VEVCVIGEFNESGKAVVKCPKG-----------------
>UniRef50_B1I460(312-562:947) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Peptococcaceae RepID=B1I460_DESAP  E=1e-18 s/c=0.39 id=25% cov=34%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDAILEARDQNLIRAITDCGAGGFASAAGEMGADTGVLLALDRAP-------LKYSGLAPWEILLSESQERMVAAVAPENLELFMDVCRR--LNVEATLIGEFTGD--RRFRATFHGETVLDL----------
>UniRef50_C4G443(64-321:325) Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC 49176 RepID=C4G443_ABIDE  E=1e-18 s/c=0.37 id=21% cov=50%
----------------------------------------------------------------------------------------------------------------------------------------------VFISGKGCLKKTSDAPWQRQRIFEGQRIILTGSVGKSGMIELFDKNKQDLKQIYPDIYieKMSNKSADRLpyaetetAPFYKVSAMLPLGPGGLTAGLWNLGEREEAGLVIYADRINYEQETIEISNHFNLNPLELNSEGAYLLATDRG--EELTLALRSA--GIDAVCIGEVTKNKKRVV----------------------
>UniRef50_Q3A4Y0(695-1009:1020) Phosphoribosylformylglycinamidine(FGAM) synthase, glutamine amidotransferase domain n=35 Tax=cellular organisms RepID=Q3A4Y0_PELCD  E=4e-16 s/c=0.28 id=20% cov=28%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HDLSDGGLGIALAETAFAGGFGMHVDLRNVKCDEVLREDA------VLFSETASRLLVTVKPDNKTAFEKLFN----GQDVSMLGTITEDQELRIVG-LGGEVLV------------
>UniRef50_C5CAC5(20-380:382) Thiamine-monophosphate kinase n=3 Tax=Micrococcus luteus NCTC 2665 RepID=C5CAC5_MICLC  E=1e-15 s/c=0.24 id=17% cov=34%
-------------------------------------------------------------------RGYDAGWKAVAQNLSDVNAMGGTASALVTALTLPPTTPVAWVRSFAAGIVGAVRHLGAPdcrVAGGDL-----GTGGRVHAAVTVLGDPHPGGVLCRTPAAEDRgRVLAEGADLVHAQAVL--------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001909C53(1-102:208) HypE protein n=1 Tax=Rhizobium etli IE4771 RepID=UPI0001909C53   E=1e-15 s/c=0.85 id=47% cov=30%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSAALHRLVAEMVAAGGrhIRLMRDPTRGGIAATLNEIASQSKVGFCIDEEAIPLKPEVAAACEFLGLDPLNVANEGKLVAVVAREGAEAVLSAMRAHPLG---------------------------------------
>UniRef50_A6URF9(714-967:993) Phosphoribosylformylglycinamidine synthase n=8 Tax=Euryarchaeota RepID=A6URF9_METVS  E=3e-12 s/c=0.30 id=22% cov=24%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLGGILITLSKMAIAGKLGAVIDSAVIP--------NESLSLEkILYSETQSRFIVTVAPENEKEFEKLMEE----FEIQKIGKVTEKDFVV-----------------------
>UniRef50_A0LFD0(646-995:1009) Phosphoribosylformylglycinamidine synthase n=4 Tax=Deltaproteobacteria RepID=A0LFD0_SYNFM  E=2e-14 s/c=0.24 id=22% cov=38%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVYRVVEKAIREGLVASCHGIYRGGLGVHAAMAAMAGGLGMRLDLEKVPVAHAGAQAKSGPGprdDHILFSESCGRFILTVSP----AMRGAFEAMAGGLPCAPVGEVLAEPVFVVAGRSG-NVLLEEPVGEL-----
>UniRef50_A9KT73(305-601:1293) Phosphoribosylformylglycinamidine synthase n=6 Tax=Bacteria RepID=A9KT73_CLOPH  E=9e-14 s/c=0.27 id=22% cov=49%
-----------------------------------------------------------------------------------------------------------------------------------------------------MGAAPRKNVI-RENSEPGDIIILmggrTGRDGCGGATGSSKVHttesiqtcGAEVQKGNAPTERKLQRLFRREEVSKLIKKCNDFGAGGVSVAIGELADG----LRIDLDKVP-----KKYAGLDGTELAISESQERMAIVVDKNDVEQMLAY--ANEENLEAVEVAVVTEEPRLVLNWR--GKVIVD-----------
>UniRef50_C6V5T2(278-601:946) Phosphoribosylformylglycinamidine synthase n=2 Tax=Neorickettsia RepID=C6V5T2_NEORI  E=2e-13 s/c=0.25 id=22% cov=50%
----------------------------------------------------------------------------------------------------------------------------------------------------CAGIIPAKIAEKESWIKApedGDLIVIAGGrtgrDGIHGATFSSAgitDSNVKGTEVQLGDPFTQKKLsdaiIREVRDADLYNAITDNGAGGLSSSVGEMGKDG---FVVHLEKV-----LLKTMGLAPWEIWISESQERMTFAIPPGKFETFGRIMTKH--GVEFAAIGEFNKSGRGLI--TFDGKTVFDL----------
>UniRef50_A4YEV4(161-452:466) Selenophosphate synthase-like protein n=12 Tax=Sulfolobaceae RepID=A4YEV4_METS5  E=3e-08 s/c=0.21 id=17% cov=50%
------------------------------------------------------------------------------------------------------------------------------------------------IGATVIGKSDHELPVFYSRVDENMEILVTRPVGeltpinvhmwlltvpelletLEERGITLQRVEEAKKRALDYMTKPnfatakviyehLPEFGKEFDPKAHIAMTTDVTGPGIF-VIKEFADKASVDVELYNVPVIDREINEFATENFIIPNSTAGTNGAIVMFASRKVIDDVAQSLSRA--GLEPSVIGRVIGKGNGTV----------------------
>UniRef50_Q39ZF9(17-349:349) Hydrogenase expression/formation protein HypE n=3 Tax=Deltaproteobacteria RepID=Q39ZF9_GEOMG  E=4e-75 s/c=0.85 id=47% cov=99%
-DLILLGHGSGGKLSHQLLDDLIIPTLSGIPLAGQNDAAVVE-----HGGQRLAFTTDSYVVDPIFFPGGNIGSLAVNGTVNDLAMMGARPLFISAGLIVEEGFSRTELAGILASMRGAADAAGVRIVTGDTKVVPRGKADRIFINTSGIGAVEHDFAINGANARAGDVVIINGTIGDHGIAVMAEREGLDLRTAIRSDCAALNDLVAEIIAAGGdaVHVLRDPTRGGVATTLKEIALQSDKTITLREETLPLNGAVKGVCSILGLDPLYVANEGKLLAVVAPEAAERVLTRIKGHRLGRDAAIIGHVAEGGGrVQMETAVGGMRAVEMLAGEQLPRIC
>UniRef50_B4U670(3-328:328) Hydrogenase expression/formation protein HypE n=2 Tax=Bacteria RepID=B4U670_HYDS0  E=1e-70 s/c=0.83 id=38% cov=96%
---VKLSHGGGAKETRELIEKIFLKHLKNDLLSNED-------ATILHLDGKLAISTDSFTVNPIFFKGGDIGKLSVAGVVNDLSVMGAKPLYMSMGFIIEEGLAFEELERIVISIKEEAQKTGIKLITADTKVVPKGLCDKIYINATGIGKLIKEG-ISASNLQEGDAIVVSGPIGNHGAVIMAHRNGFDID--INSDCASLWEAIEPLLKENiEIHAMRDLTRGGLASALNELSQSSKVEILIKEEDIPIEDSVKGFCEILGIEPFSLACEGTFVMSIPKKDVQKALDILKSQKLTQKAKVIGEIIKKGkqGAYIQTLYGSVRYLEEAPGELLPRIC
>UniRef50_A4YFA3(8-352:352) Hydrogenase expression/formation protein HypE n=1 Tax=Metallosphaera sedula DSM 5348 RepID=A4YFA3_METS5  E=4e-70 s/c=0.77 id=43% cov=97%
-NVITLLHGAGGTYMHSLIRDVFLKLndgFGEVGLEMMDDAAVV---------NGIVFTTDSFVIRPIFFRGGDIGRLSVSGTVNDIAMMGGDPQALSLGVVLEEGFPKDMLEKIVESIKKTAEEANVHVVTGDTKVMERGNLDKIVINTAGIGTRPRQldhnietlrksrqpsRWLVPTNLRDGDKIVVTGTLGDHAIAVLSSREGVGFESNVMSDVAPLNKMIMNLLEVGGIADAKDPTRGGLADLLQDWSEKSGLGIFIRESDIPVKDEVRAAVEFLGMDVLELGNEGKAVLAVSPEYVKDVMDALHSDPLGKDATIIGEVRKDlEGVIMETVVGGNRYVGRPLGDPVPRIC
>UniRef50_C5CEU2(6-326:326) Hydrogenase expression/formation protein HypE n=1 Tax=Kosmotoga olearia TBF 19.5.1 RepID=C5CEU2_KOSOT  E=8e-61 s/c=0.74 id=35% cov=95%
---ITLHHNSGKKQFKLL--KHIEKLLGSTLVSTENDSGFLEEVVDT-------VTTDSFTISPVFFPGGDIGKLSVCGSINDLVMTGAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELDENGVKIIAGDTKVMEHGALDKIVINTTCLGEVLYEK-LCVKRIETNDLIIITGPIGLHGAAIMAERKGFQID--FQSDCRVLTKLL-AVIKGLRVHAMRDPTRGGLAQILNEFSHSTKRNFAIYEDKLPIPGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNA--GFDPSTIGFVggiIERPLLILKTRNGAKRVLPMLVEELTPRIC
>UniRef50_D0SP02(5-288:305) Thiamine-monophosphate kinase n=1 Tax=Acinetobacter junii SH205 RepID=D0SP02_ACIJU  E=5e-54 s/c=0.75 id=21% cov=83%
----------------SIIDRYFKRAsHQDVSLGIGDDSAIL----TPLTSQQLVICTDTLVAGRHFpldTSAHAVGWKSVAVNLSDIAAMGAQPHSILLALSLP-SVDETWLAEFSRGLFECCDQFNVALIGGDTTQSS-----QLTITVTALGWIEQGQAITRAGAQVGDYICVSGQVGDAAYGLHH------LGHTLQQRLDYPTPRCQLGQRLKGRATSMIDVSDGLAQDLGHILKASGVGATLFLDRLPIDSALKALdQQQAWQYALAGGDDYELCFTISPQKFEE----LSRHQSDVPFTIIGEITQQTGLLFK---------------------
>UniRef50_D0KYD5(5-304:323) Thiamine-monophosphate kinase n=1 Tax=Halothiobacillus neapolitanus c2 RepID=D0KYD5_HALNC  E=2e-51 s/c=0.68 id=25% cov=85%
----------------ELIARYFSRPCADasVVLGVGDDCA----ALRVPEGEHLLVSTDLLVEGRHFpesTAAFDVGYKAMAVNLSDLAAMGARPLGVTLGLALP-SIEPDWLEAFAKGFYTLAEQHGICLVGGDTVKSPV-----LSLAVTIMGSAPPDRMLTRSGAQSGDLIAVTGTLGDAGLGLRSIQRPESMPPSLNPedidflqmRLNRPTPRGEEGRRLAEVAHAAIDISDGLLQDLGHILRASHVGAVVEADRLPISPAARAWLAADPTQhnlPLTAGDDYELLFTIAPDQW---------AMLDVPATVIGRITQDKRLRVLDAQG-----------------
>UniRef50_A4SVD0(12-321:339) Thiamine-monophosphate kinase n=1 Tax=Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1 RepID=A4SVD0_POLSQ  E=2e-51 s/c=0.66 id=20% cov=87%
----------------DLIERFFKtgtsatEQNENIPLGIGDDCALIKQA----TDSEIAITTDMLVEGRHFFAGADpeqLGRKALAVNLSDLAAMGAEPLGFTLAIAMPKA-DIAWLEAFSKGLLDSANLYGCPLIGGDTTAGP------LTLSITALGNIPQGKAIRRSGAKIEDDVWVSGNVGDARLALAALRHEIPLSAEdlkqVEKRMHQPTPRIELGIGLRDIATAALDISDGLLGDLNHVLKQSQVDAQIFLNQIPKSETLKKQStDIQNQFAASGGDDYEICFTAPNHQREAIKKLSKS--LDLPLTLIGRIIpiknKNPQVHLINSDGAT---------------
>UniRef50_C5A3X6(1-309:319) Thiamine monophosphate kinase (ThiL) n=4 Tax=Thermococcus RepID=C5A3X6_THEGJ  E=6e-49 s/c=0.64 id=24% cov=89%
-------------MMESEIIELFIRHLKRQGDLPLGD----DAGALRLGDRWLVATNDMLVRKtdvPDIMTPEQVGFKAVTMNVSDMASMGAEPLGFLFSLGIPGDLDSDYLEGIARGIGEALDFYGLPVLSADT-----NEADDLIIDGAALGITE--RLLTRSGAKPGELVCVTGDLGRALAGYLVWKNGLEVSDAVRkplyEKFLEPRARVREGSELSKVASSAIDISDGLAKELYLLAEMSQVGIEVRPESLPLGKGVEEVAELLGLDPfeiaLASGEEFELVFTVAPEFVESL---------NFDFSVIGRVTRGKGIYLVDDSG-KRVMPKLGWEHL----
>UniRef50_B8I2N9(4-328:330) AIR synthase related protein domain protein n=6 Tax=Clostridium RepID=B8I2N9_CLOCE  E=6e-49 s/c=0.61 id=23% cov=93%
-----------GKLPNDILNKIVFGKINTFRKEVIMrPGIGEDCAAIEFDKYACVMSTD-----PITAAGKNAGRLAVHISCNDIASSGVEPLGLMVTILCPVGTTETELEHLMDQVCETAGQLNVEIIGGHTEVTP--AVNKIILSTTCVGKSLKDKIISSSGAKPGDSVILTKSAGLEGTAIIAGDFEEELAEVMnKNELQYAKSLINAisvvpegvLAGRFGVTSMHDITEGGVLGAAWEIAEASSTGVTIKKDSIPVEPVTRHICDHFGINPLRLISSGCMIITC--KDGEGLVRLL--GENNIKASIIGTITqnKTGRLLISEKEGTSENIEAPGADELYKI-
>UniRef50_C9YEU1(26-341:354) Thiamine-monophosphate kinase n=1 Tax=Curvibacter putative symbiont of Hydra magnipapillata RepID=C9YEU1_9BURK  E=2e-47 s/c=0.61 id=24% cov=87%
-----------------LIARYFersqHPLPTQVVLGIGDDCALLQ----PTPGMQWAISSDMLVSGRHFFAdvnPLTLGHKALAVNLSDLAACGARPVGFTLALSLPDA-DPAWLQGFSQGLFALADAHNCPLVGGDTTRGP------LNICITVFGETPPGQALLRSGARAGDDIWVSGTLGDAALALHCLWGRDQLPAEAFALARqrleQPTPRAALGQALRGIATAAADVSDGLLGDLGHILERSHVGAELEaLYAINLLAARAYLTGASGtFDPnsqtdstalryvLSGGDDYELVFTAAPEHRLQVQAA--GTHSGTPVTRIGRIVRDPGVTVKAPDGS----------------
>UniRef50_C7JHE3(18-316:329) Thiamine monophosphate kinase n=8 Tax=Acetobacter pasteurianus RepID=C7JHE3_ACEP3  E=3e-47 s/c=0.64 id=19% cov=88%
-----------------FIRQHFSALAGAAALELRDDAAVF----TPPEGRELVIAADGMVENVHFLpddPPETIGRKLLRCNLSDLAAMGSRPEGWLLTFARPPHITEQWVAQFCKGLKADQAQFGLQLLGGDTTSTRG----PLVLSLTILGSVLPGQAIRRQGAQAGDGLWVTGTIGDGALGLRALQGEIADPSGYLAQRYRL-PQPRIGLPLYGLASAAMDISDGLLQDAGHLARESELHVTIHADAVPLSDAARQTGPKWLETCLTGGDDYEILFAVPAQHEAALLSkgTLDTVCGPVKVTRIGEFTQAStGVTVLDSAG-----------------
>UniRef50_B7JUY6(25-317:344) Thiamine-monophosphate kinase n=4 Tax=Cyanobacteria RepID=B7JUY6_CYAP8  E=7e-47 s/c=0.65 id=20% cov=81%
----------------------------------GDDGAILS----VDPAQKLVVTTDVLVDGVHFsdrtTPPATVGWRAAAANLSDLAAMGANPIGITVGLALPGEVPVNWVETLYQGLNDCLQCYDTPIVGGDICRSPT-----ITVSITAFGTVLPHRIIRRSSAQPGHAIVVTGTHGGSRGGLELLLNPQLGDhltiteqQALIETHQRPQPRLDVLPHLWEIVGttevAGMDSSDGLGDAVVQICRMSGVGAKIERSQISLPPSLLALVspEQALQWGLYGGEDFELVLCLPFDLAKTLVERL-----GNGANIIGEITTEPRVILIDSNG-----------------
>UniRef50_O27447(12-311:327) Probable thiamine-monophosphate kinase n=1 Tax=Methanothermobacter thermautotrophicus str. Delta H RepID=THIL_METTH  E=2e-46 s/c=0.63 id=22% cov=67%
---------------------------------------------------------------------------------SDLAAMGSRPEGFILSVALP-DLELEFFDSLMDGVIEACCHYQAPLIGGDT-----NEADEIILSGTAIGRAEKDMVLMKSGARPGDLVAVTGPLGVGAAGTELILSGRDTGgfENAVERSLRPVARIEEgliLAESGLVSSATDITD-GLVSELGELMDASGTGMRIYEDRLPLGREVPEIASILGRDPLELalyyGEDFELVFTAPPTGMEELSDMMELH-------VIGEVTVGGGIEMVDKDG-----------------
>UniRef50_A0M637(20-338:351) Thiamine-monophosphate kinase n=43 Tax=Bacteroidetes RepID=A0M637_GRAFK  E=3e-46 s/c=0.59 id=21% cov=85%
-----------------LIDHLtknFSPKLESTIKAIGDDAAVLNF-----KNKQTLISTDLLVEGVHFdlayMPLKHLGYKAVMVNLSDIYAMNGTATQITVSFAASNRFPVEALEELYAGIQLAAKLYNVDVIGGDTTSSTSG----LMISVTAIGIAEKEEITYRNGAKANDLLVLSGDLGAAYMGLQVLEREkqvfkanpnsqpdLDQYTYLIERQLKPEARQDippLLKELEVQPTSMIDISDGLSSEVIHLCKNSKLGANLFEEKIPLDPAVISVCEEFEIDstmvALSGGEDYELLFTISQDDYDKI-------KGNPHLTVIGHMTEENeGMHLVTR-------------------
>UniRef50_B6YUV4(6-317:332) HypE n=3 Tax=Thermococcus RepID=B6YUV4_THEON   E=2e-45 s/c=0.59 id=25% cov=88%
-----------GKLRNDVLREVVFPNIGIEDVRVIyGPREGFDSAVLEYDhEHYLIVATDP----TLGVPEETFGFFTYHFAASDVAVFGARPRWLIVDLLFPPGTERSFLENIMRSLNTECRKYGSSIIGGHTGAYPTIA--EPTSTTTAMGLVRKDELKLPL-AEPGDKIIVTAKIGLEFAVSAAYFREEELRkfltfkeiERLKRLFTFETALPDALIARPFVRGMHDATEGGLT-ALHEIAENSGVGFRVYADRLYLDPLVRKVLEFYGLEPWSVSSTGTLIAITPPEKADALITELNKN--GIMAFELGEFTEEKERVL----------------------
>UniRef50_B1I671(9-325:337) Thiamine-monophosphate kinase n=1 Tax=Candidatus Desulforudis audaxviator MP104C RepID=B1I671_DESAP  E=4e-45 s/c=0.58 id=24% cov=89%
-----------------LVERLLGRLARGPGVvrGAGDDAAVLDLG----GKELLLFTVDTLVEEVHFSRAYgsmrDLGAKAMAVNLSDVAAMGGRPVYAVVSLAAPAETAVADIDDLYAGLAGTAARYGVTLVGGDTVRHP----HGLVITVALLGLAGRERVLYRKGAVSGDLFYVTGSLGASAAGLFLFQNPHpacppEVEDRLKKAHLSPEPRVVAggLLAASGVVSAAEDISDGLALTVAHICTAGGVGARLLADRVPLSPEVRRLGILTGKDPlewaLFGGEDYELLFTVRPGAAAGLEREMAAA--GWPVTWIGEVLgPGEGLWLEDAAGAGRPL------------
>UniRef50_Q46DN9(10-317:340) Thiamin-monophosphate kinase n=4 Tax=Methanosarcinaceae RepID=Q46DN9_METBF  E=9e-45 s/c=0.59 id=21% cov=70%
-----------------------------------------------------------------------IGWMSAAVNLSDIAAMGAEPTGLVMAIGMPADTEIAFVEALAKGMQACTEFCGTMIIGGDL-----DTHTELTITGTALGRVKKSQLLLRRGARPGDLVCVTGYTGSAGAALEALQSGKPVSETVLKALFEPVPRtkeARKLAESGAVTSMMD-TSDGLAMSLYDLSRQSRVGFMIRENALPVLREVRKFAsnpNRLREFSLYTGGDFELLITIDPQKIKKVQNIC-------NLVVIGECTKyEAGIVLESP-------------------
>UniRef50_Q1YU39(3-298:305) Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium HTCC2207 RepID=Q1YU39_9GAMM  E=3e-44 s/c=0.61 id=23% cov=54%
---------------------------------------------------------------------------ALCVNLSDMAAMGAEPRWFTLALTLPrDKAKAEWLAEFSVGLGHIANQYNLALVGGDTTSGP------LTLTLTLVGEVPVDKALTRGGASIGDSVFVTGTLGDGAAGLkiaSNKNSNCIDSDRLLQRFYSPQPQIQAGLKLRSIASACIDISDGLLADLGHICKASDVSAVIKAEQLPIAADVQQLSAL---------------------------------------------------------------------------
>UniRef50_Q2GJY6(7-303:318) Thiamine-monophosphate kinase n=1 Tax=Anaplasma phagocytophilum HZ RepID=Q2GJY6_ANAPZ  E=1e-43 s/c=0.60 id=20% cov=85%
------------------IEKYIRPLLRSGFASENDDAA-----HVSSPTSSFIMTKDVLVENVHFLnhsDPFLLAKKALRVNLSDIASMGATPHSYLLGLSLPKFIDEEWWKSFCAGLQEDNSIFSIKLTGGDTT---NNLADIIVISITALG-IPSANILTRSNAKVGDYLYVSGTIGDAALGLLAYNKKLIGEfSYLKQRYDLPQPRVMLGTSISNVASACIDVSDGLLQDIGLLCKLSGVGANLYAYEVPLSHEAAAAimqNHDLLENVLAGGDDYELAFTVPPKYCPEVEQI--ATNIKIPVKRIGVITREQGIRV----------------------
>UniRef50_A0NME7(10-317:332) Thiamine-monophosphate kinase n=2 Tax=Labrenzia RepID=A0NME7_9RHOB   E=2e-43 s/c=0.58 id=20% cov=85%
----------------ELIRRFFAPLAKDPGsLGLTDDAAVL----TPHQGYDLVLTKDVLAADIHFFaedAPEAIAAKALRVNLSDLAAKGARPRGYLMGLSLPSDWTVDWLERFCNGLAADQAAYDFHLYGGDTVR----SGNGLQVSITAIGEVETGKAVRRSGAQPGDLLFVTGTIGDAAAGLQArlnpdfcrdHDLTESEEGHILDRYLLPRPCTRLAGAVADYASAAMDVSDGLIADCAHMAKASALELTIDLDLVPLSQALTHLKIKAPEDfarCLNGGDDYEILMAVPQERSDTLRRV--AHLAGCPVTQIGYARAGE--------------------------
>UniRef50_B4UJS8(16-317:329) Thiamine-monophosphate kinase n=7 Tax=Cystobacterineae RepID=B4UJS8_ANASK  E=2e-43 s/c=0.59 id=26% cov=87%
----------------ELIERFTRAlplAGAGVRLGPGDDTALL----APPPGEDLAATVDAVVEGVHFdarFTPEDVGWKALAVNLSDLASMGARPLWALVALAFPRGTPPERLEGVARGLGACARAHRIAVVGGNVSR-----ASELSVTVTAVGAVRRGRALLRSGARPGDLLVASGTFGDAALGLA-----PGASAALVRRQRRPAPRLALGRALAGVARAAIDVSDGLVQDLGHLCDESGVAAVLEAAAVPTSAAYRRAARSLPDplgPALGGGEDYELV--AALPPARLARALRAAARARVPLAVIGRVERGSGVRILGADGAER--------------
>UniRef50_C6QHP2(20-341:341) Thiamine-monophosphate kinase n=1 Tax=Hyphomicrobium denitrificans ATCC 51888 RepID=C6QHP2_9RHIZ  E=7e-43 s/c=0.55 id=22% cov=86%
-----------------------------------DDAAFLRPAS----GSDLVFSSDPIIAGVHFFhddRPADIAWKALACNASDMAAKGAAPVAYLLTLALPEAPERDWIAAFADGLRAAQSEFGCKLIGGDTDVTPG----PLSIGITIIGSVAAGAFIPRGGAKAGDHVFVSGTIGDAALGLALRRDpsqfstlTDDQRALLLDRYLRPKPRLALAGPVRSHARSALDVSDGLIKDLRRLAGAS-LGIAVKFDDIPLSPPARAALAANPnvrDSILAGGDDYELLIAVAPENIEKFVT--SAGESGIRVHDIGVLESKITTVVLDPSGVPIALRRPGYDHFSR--
>UniRef50_B0TDV9(49-345:373) Thiamine-monophosphate kinase n=1 Tax=Heliobacterium modesticaldum Ice1 RepID=B0TDV9_HELMI  E=2e-42 s/c=0.59 id=29% cov=53%
------------------------------------------------------------------------GRKALAVNISDIAAMGGIPAWAFLSIGVPASAKVEEVEGLYAGMGEMAAQFGVELAGGDTVRS-----DKWVINVTLLGLAVK-APIGRSGGRPGDLILVTGTVGDAAAGLHLLLMETKMSqaekmdaqmreapigeadrQALLLRHLDPIPRVAEARALvdyGGVTAMMDVSD-GVSSEVHHLCRNSGCGARIDLANLPISPAVR--------------------------------------------------------------------------------
>UniRef50_Q10XH5(10-325:341) Thiamine-monophosphate kinase n=6 Tax=Cyanobacteria RepID=Q10XH5_TRIEI  E=2e-42 s/c=0.55 id=18% cov=84%
---------------QELLKKL---RHFCPENIIGDDAAILPT----QPNKSLVVTTDTLVDGVHFSDrttsPEDVGWRSAAANLSDIAAMGAFPIGITIALGLTVDTPIAWCEQLYQGISECLQPYNTPIVGGDIVRSPVS-----TISITAFGQIDGGYTILRSNCQPKNVIVATGVHGASRAGLELLLYPELGEsltelerSDLILAHQRPKPRLDILDTLWDCLSLNsfsatkgsknsilvggMDSSDGLADAIIQICQASQIGARIERNQIPIPHSLtKFVSDEQALNWaLYGGEDFELVLCLPPNCGQELVKRI-----GVGAAIVGTTTNNTDILL----------------------
>UniRef50_Q1QUD0(6-300:319) Thiamine-monophosphate kinase n=1 Tax=Chromohalobacter salexigens DSM 3043 RepID=Q1QUD0_CHRSD  E=3e-42 s/c=0.59 id=25% cov=65%
---------------------------PGVALGVGDDCALLS----PEAGHELALSVDTSVVDVHFpgdAPPEAIGHRALAVALSDLAAMGARPRGCLMALTLS-HAEPDWLERFAHGFRELGRRTATPLIGGDVTRGS------LSIGVTVIGDVPAGQALRRTGAAPGERLAVTGSLGGGHAGLRMWQaGGHDLADPLLAAYLTPTPQLAAGQALRDLASAGLDISDGLLADLGHLCRASGVGAVLSPDDLPLAPS----------------------------------------------------------------------------------
>UniRef50_B1CC54(4-322:324) Putative uncharacterized protein n=1 Tax=Anaerofustis stercorihominis DSM 17244 RepID=B1CC54_9FIRM  E=3e-42 s/c=0.55 id=19% cov=92%
-----------GKLSNETLEKILFNKIKIKNKEVKIGAgIGKDTAMLDFQNDLFIISTD-----PITGSKNGIGKLCVNISCNDIATAMARPVAIMITMLIPTYAKIKDVEEIIDDILLTCDENNVDLIGGHTEV--TSSVNKFILSGVCIGRKEKRKEFLPSA---GDKVVMSKYAGLEGSAIAALDLEEEVKNILTKEEFEKTRELinhtnvikeGLIARNHEVSLLHDATEGGIFGGVWEMATNSNLGAVINTDDILILDETKKIAEHFGIDPYKLISSGVMLFITKNDK--ELIEDLKKE--NIPASTIGYLTEEKEIY-TIKNNKKEILSPPEQDELYKI-
>UniRef50_Q3A8K1(11-320:329) Thiamine-monophosphate kinase n=2 Tax=Desulfuromonadales RepID=Q3A8K1_PELCD  E=1e-41 s/c=0.56 id=25% cov=73%
------------------------------------------------------------------------GRKSVSVNVSDIAAMGGRPRHLYLGLGVPADFSVEELQLFMDGFLEAVTAYGACLVGGDTCRSPG----PLLISVTAEGSVAAGREVRRAGAGIGQIIYVSGTLGDSALALQQLGKGEVPDSFLASRHHDPTARVALGqaLAQAGLATAMIDISDGVLADLGHILKASSVGALLEESLLPLSGAFRAVlqhAPHLLQLALSGGEDYELLFTVAPEREAEVDALART--LALPLTRIGVITsADEGLRLRAADGSLR--------------
>UniRef50_C1F5W5(27-356:358) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F5W5_ACIC5  E=1e-41 s/c=0.52 id=25% cov=28%
----------------------------------------------------------------------------VNHCVNDIAVQGATPLFFLDYLA-TGRLENEVIEKVVQGLAEACKANGAALIGGETAQMPGFYADGeYDLAGFIVGVVEREKIITGKNIQNGDVLI---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C6A3P3(26-337:349) Hydrogenase expression/formation protein HypE n=2 Tax=Thermococcus RepID=C6A3P3_THESM  E=4e-40 s/c=0.54 id=23% cov=88%
-----------GKIRSEVLNNIILKNISvNDPKIVFGPKEGFDAAVLEYDEKnYLVIATDPI----LGVPKEHFGFFTYHFASSDVAVFGAIPKWLIVNLLLPNGTTEEDLNSVMRELNEECKKYGTSIIGGHTGVYSTTRSFTATTTA--IGLVKKDELKLPL-AKPGDDIIITKGIAIEFAVGAAWFRTEELKKILspsqissLREMYTLETVVkDALLAKKFARGMHDVTEGGLT-TLHEIADNSEVGFEVYYEKLHMPPLVKKVVKFYGVNPLTVSSTGTLIIISPQENTSKLIKALHSH--GINASTVGKFTEEKERAL----------------------
>UniRef50_Q4L580(15-333:343) Phosphoribosylformylglycinamidine cyclo-ligase n=7 Tax=Bacteria RepID=PUR5_STAHJ  E=3e-39 s/c=0.51 id=19% cov=70%
-----------------------------------------------------------------------IGIDAVAMCVNDILTTGAEPLYFLDYIA-TNKVVPEVIEQIVKGVSDGCEETNTALIGGETAEMGEMYHEGeYDLAGFAVGAVEKDDYIDGSAIQEGQAIIGLASNGIHSNGYSLVRKlikesgidlNDDFDGRtyletFLAPTQLYVKPILALKKAVQIKGMNHITGGGFYENIPRGLPE-GLAANIDTQAFPTPNVFNWLQQQANIDtkeMYNVFNMGiGFTVIIDKKDVAQTLDILKQE--GISAFEIGEIIEDK--------------------------
>UniRef50_C6A0I0(36-353:713) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Thermococcaceae RepID=PURL_THESM  E=5e-39 s/c=0.52 id=21% cov=72%
----------------------------------------------------------------------------VGGIVRDILCMGARPIALLDPIRfgpLGKERNRYLFEYVVKGIADYGNRIGVPTVGGETEFDESLDNYTL-VNVACIGLMRPEELVHSYVEESGLLLVLvgnkTGRDGIHGVTFASEELSENAEEEDRSAVQIPDPFTEKLLieatleavHTGKVKALKDLGGGGLTCASSEMAGKKGFGAVIYADRVPQREP-----NMNPMEIMISESQERMLFAVRKEDLNEITKIFEKYDL--EWTVVGETIEEPRYIV--YWNDEKIADLPI--------
>UniRef50_A6GU77(4-345:358) Thiamine monophosphate kinase n=1 Tax=Limnobacter sp. MED105 RepID=A6GU77_9BURK  E=1e-38 s/c=0.47 id=26% cov=46%
----------------DLIHRYFKTPFGRlaranantVLVGIGDDCATLQL----LPGHHLYTSTDTLVEGVHFFsddSPHATGWKALACNLSDLAASGASPLGFTLNLSLPE-INESWLADFSAGLLDVATRFNCPLVGGDTTSSGPNPSKTLSITVF--GQAPiTHRGFNRAHAKIGEEVWLSGTPG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D0J8W5(2-325:328) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Blattabacterium RepID=D0J8W5_BLASP  E=4e-38 s/c=0.50 id=16% cov=89%
------------KESHRTIRKigpILEKTYTKKVLSNLDYfSALYQLSLCSYKEPVLVSGADGIGTKLRLAIDYKkydlIGTDCFAMCVNDVLCHGAKPLFFLDYLAC-GKLDSNIVEKIIQGIAVSCKKTNTCLIGGETAEMPGIYQEKDYdIAGFCVGIVDKENIIDGKKtIQEGDILIGLPSSGVHSNGFSLIRKIFSKEDFLMHRiqekpfyeillipTRIYHDPIHLLLKEFLIHGLAHVTGGGISDNLFRILPD-NLSAIVEKKKIPVQPVFNHIQEkgfLSDQEMWETFNMGvGMIVIVSVKDKYSLLQRLCA--LGENPFVFGHLVKGNKRV-----------------------
>UniRef50_A8ABX6(400-669:713) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Thermoprotei RepID=PURL_IGNH4  E=2e-22 s/c=0.40 id=20% cov=49%
-----------------------------------------------------------------------------------VVASGARPLAAVDQVDAGSPERPDRFWffvRMIDGLAWVEREVDVPIVGGKVSFYNEDDVTGkqikPTVMITMIGKVENVYNAKRARAEEGDLLVLVGETFpeLGGSEFLWSVHKLVRGKPPVPRPSTEARVAERILKAikvSGVTGVHDVSVGGLAAAVAELAKGFGATLELD-------------------------------------------------------------------------------------------
>UniRef50_Q46F25(398-695:715) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Methanosarcinaceae RepID=PURL_METBF  E=2e-19 s/c=0.33 id=19% cov=45%
-----------------------------------------------------------------------------------------------------------------------------------------------------IGKVNFETPLPSSfFAKSGDAIILVGeTTADMGGSEYYACFEALNAGKVPSVPKnapEIIKAVIEAARSGKLSSAHDLSLGGIAAGLARMCRNSGAKVDL-----------SEVSELKAEELLFSEAPARALLATSE--PEAVLEILK----DVPHMVIGKV-EGNSLEVKGK-------------------
>UniRef50_C8W2B7(13-338:344) Selenide, water dikinase n=8 Tax=Bacteria RepID=C8W2B7_DESAS   E=2e-37 s/c=0.48 id=25% cov=69%
------------------------------------------------------------------------GMIAAANAISDIYAMGATPAFALNIVGYPNqSLPLSILGQILKGGADKAAEAGIAIIGGH-SITDHAPKYGLVVT----GFVNPSRMISKKGAKPGNALILTKPLGIGviTTGIDRKLVNNELIGRVTKQMTTLNKQAAEIMQEVGVNACTDVTGFGLLGHLREILIASGTGACITASKVPIIPETEELiqagavsggthnnyrylrdlvewdtrlskeVKLILCDPQTS---GGLLIAVPQENKNKLLKALQSKEEVLTAVEIGEVVEGPG-------------------------
>UniRef50_B6IMS3(25-338:344) Thiamine-monophosphate kinase n=1 Tax=Rhodospirillum centenum SW RepID=B6IMS3_RHOCS  E=4e-37 s/c=0.50 id=22% cov=87%
---------------------------GYPGAFGLTDDAG---TVAVPAGMELVVTTDAMVAGVHFLpddPPEDIAAKLLRVNLSDLAAKGAVPLAYSLVTALPRDCAEDWLARFCAGLGGDQQRYGIHLLGGDSVSTSG----PVTLTVSALGLVPAGRMVRRAGARPGDLVFVTGTVGDAALALLrvLGREPAALPQAadwapLVARLRRPEPRLAFAPALRDLASAGLDVSDGLVADLGHIAAVSGVAIEIRADRLPlsaAARTLLAAAPDLLATVLTGGDDYELAFTAPAAREAAVLAAGRA--CGVPVTGIGRVLAGaPAVTVLDASGAPLPLDR----------
>UniRef50_A6X235(29-360:363) Phosphoribosylformylglycinamidine cyclo-ligase n=416 Tax=cellular organisms RepID=PUR5_OCHA4  E=4e-37 s/c=0.47 id=25% cov=70%
--------------------------------------------------------------------------------VNDLVVQGAEPLFFLDYFA-TGKLSPDQGVDIVAGIAEGCRQAGSALIGGETAEMPGMYRDGDYdLAGFAVGAAERDRLLPRGDIAEGDVILGLASSGVHSNGFSLVRRIVELsglgwksdapfqpgatlgEALLTPTRIYVKPLLAAIRASDGIKALAHITGGGFPDNIPRVLPE-GLAAEIDLESISVPAVFSWLAKTGGVEPnemLRTFNCGiGMIAVVKPEKVEEVVAALAAE--GEKVVTLGQMVkrDKDGVVYKGT-------------------
>UniRef50_C9RGW7(21-326:333) Thiamine-monophosphate kinase n=1 Tax=Methanocaldococcus vulcanius M7 RepID=C9RGW7_METVM  E=4e-37 s/c=0.51 id=20% cov=83%
-----------------LIKKTLTYSNQNIIKGIDDDCAVIK----IDENRYLVATTDMMVKNTHipsILTPHEIGGRILTANVSDIASMGAKPLAFLLSISLSKKeAKEDFIKELYKGLDEFSRLYDCPVVGGDT-----NKGDELVLSGTAIGIT--DNPIFREG-RVGDKIGITNDIGRVYCALklyyLLKNRKIEVKEfkklcskypLIINKLKVPIARVKEgilLNKYRLLRGCCDISDGLG----KEITYFKNFELNSDHILKAVPEDVFEFCEEFSLDPLTvalnSGEEFELLFTTS--NINKVKRVLKHHS---KVFEIGKVIEE-GRYIDGEM------------------
>UniRef50_C1F3W9(15-338:338) Thiamine-phosphate kinase n=1 Tax=Acidobacterium capsulatum ATCC 51196 RepID=C1F3W9_ACIC5  E=5e-37 s/c=0.48 id=23% cov=51%
--------------------------------------------------------------------------------LSDLAAMGASPLAAFLSLAAPPErmrpqgrAKKSWLDRFLDGLLALADAHGVSLAGGDTAQSPMG---GVIADIVLLGQTPRGRALLRSGARAGDRLYVTGALGGAAAELLALGHGqsLRLKGATAHPQLFPQPRLAVGQRLLGarLATAAIDISDGLSTDLDHLCEESGLAAVIDAAALPVHP-----------------------------------------------------------------------------------
>UniRef50_Q4FMQ1(54-338:342) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Candidatus Pelagibacter RepID=Q4FMQ1_PELUB  E=2e-36 s/c=0.54 id=17% cov=70%
-------------------------------------------------------------------------------SVNDLIVQGARPLLFLDYISI-NKIDLNKLKLILKGIVRGCKISNCELVGGETAEMPGtYEKGKFDIAGFAVGLVDEKKILSKKNIKKNDLVLAIPSSGVHSNGYSLVRHVLNkkkinlknnsfLKKELLRPTKIYVKEVLNLIDNNLLNGCANITGGGLADNIKRVIPD-KLVADIDLNKVRTKKIFKWLkqNNIDDEEMLKTFNCGvGFCLIVNPKNLNKITKFFTKE---FKPYVIGKITAGKyKVKLHGK-------------------
>UniRef50_Q46I59(71-385:803) Phosphoribosylformylglycinamidine synthase 2 n=41 Tax=Cyanobacteria RepID=PURL_PROMT  E=4e-36 s/c=0.49 id=20% cov=69%
----------------------------------------------------------------------------VGGILRDIFTMGARPIALLNALRFGPLDDEkniSLLEGVVAGISHYGNCVGVPTIGGEVGFDSSYSGNPL-VNAMALGLMETEEIVCSGASGIGFPVLYvgntTGRDGMGGASFasseLSKTSIDDRPAVQVGDPFLEKGLIEACLEAfktGYVIAAQDMGAAGLTCSCSEMASKGEVGIELNLDLVPAREKGMTAYEF-----LLSESQERMLFVVKPGSEEELRELFIR--WGLYVEVVGKVLKEKVVRV----------------------
>UniRef50_B0C6M7(408-736:752) Selenide, water dikinase, putative n=4 Tax=Cyanobacteria RepID=B0C6M7_ACAM1  E=4e-36 s/c=0.47 id=22% cov=78%
-----------------------------VGLGGADDAAVVE----VPPGQVMVHTLDYF--RSLINDPFIFGQIAAHHSLSDLFAMGAEPQSALAMATLPYGSDqslQETLYHLLAGATKVLQQAGAELVGGHTT-----EGAELAFGLACNGLIDRKGILSKHGIQPEQVLILTKPLGTGLIFAAAMRqqtRNLWIDSALQSMLQSNQAATQCFLEYQA-TACTDITGFGLIGHLSEMLRSSPIHVQLNLNSIPAMPGVAEIISQnihsslypqnlkaghwvanqdqfqthplwpLLFDPQTS---GGLLATVPMEHASECLEDLEKVGY-RQSSIIGKTV-----------------------------
>UniRef50_C0ZXP1(26-324:343) Thiamine-monophosphate kinase n=11 Tax=Corynebacterineae RepID=C0ZXP1_RHOE4  E=7e-36 s/c=0.51 id=22% cov=79%
-------------------------------LGPGDDAAIV-----TSGDGRVVVSSDMLVEGRHFRmdwsSPRDIGRKAVAQNAADVVSMGARPTAFTVSLGCPPSTPVDVIDAISAGIWDAATDLGAGVVGGDLVQSPVVVVSVTVL-----GDLGGRPAVLRSGAKIGDKIAVAGLFGCSAAGLALLLDEAVLLDEaesfpdLLAAHRVPNPPYQSAWEAAESAHSMTDVSDGLIADLRHLAEASHVRFDIVSAAVPTSPDVASAAEALDVDPldwiLSGGEDHGFAATFGPEV-----------EIPSGWTVIGEVAAGCGVSVDGS-------------------
>UniRef50_A6UX13(50-359:732) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Methanococcales RepID=PURL_META3  E=2e-35 s/c=0.49 id=19% cov=72%
----------------------------------------------------------------------------VGGIVRDIISMNAKPIALLNALRFgdingEEKDKVRWLvEGVVDGIRDYGNRIGVPNVGGECEFDKSYDYNNL-VNVVCIGLVKEGDIVTGKAKETDLTLILVGSTgrdGIGGASFASKDLTSESEGDRPSvqigDAFTEKCVIDSTLEACAtkkVKAIKDLGAAGITSSCSELCYSGGVGAELYLENVILRDEGMTAYEI-----MVSESQERMLLAVEKGSEEEIIKIFEKYEL--PVSIIGKTTDTKRFFVK--MNDEVVVDLP---------
>UniRef50_C1SM36(24-343:345) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SM36_9BACT  E=2e-35 s/c=0.47 id=22% cov=68%
--------------------------------------------------------------------------------VNDIIVTGAKPLFFLDYMA-TGKLSSEKMAQVVEGIAEGCRQAGSPLVGGETAEMPGmYSGEDFDLAGFAVGILDKPKAVTGERISKGDVLVGLPSSGLHSNGYSLARKlffeklsmkpddilydDVMLKHALLEPTRIYVQQVLSVIEKGiDVKGMVHITGGGFYDNIPRILPE-GAGVKINPDAFPTPGIYKFILEKSGIeekELYRVFNMGiGYIMVLEHSEAEKCMSLID------DACVIGNVTDTGIVEIEG--------------------
>UniRef50_A9BIY1(14-309:322) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Petrotoga mobilis SJ95 RepID=A9BIY1_PETMO  E=2e-35 s/c=0.51 id=13% cov=46%
---------------NESIKEI--RSFIGSNIGAYAGIFPLKDVLPNYKNPFLVATSDGIGTKLHLLKKYGrwdiAAQDLVAMNLNDLVCMGAKPLFFLDYFS-TSHLNKNNFVTFIRHLKNILDEYECVLLGGETAELPGVFKNKsEDIAGFAVGIVEKDNIFDYSKVEPGDKLI---------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q3ANP7(444-742:768) Phosphoribosylformylglycinamidine synthase 2 n=7 Tax=Bacteria RepID=PURL_SYNSC  E=4e-15 s/c=0.28 id=14% cov=48%
-----------------------------------------------------------------------------------LSCVGAEPLAVTDNLNFPSPETPKGFWQLAmacRGISDACRTLNTPVTGGNVSLYNETKQDDgtmqpihPTPVIGMVGGVDDiSRVTCLAWQQPGDAIFLIGvppedgadpSLGLAGSAYQQQTLGSLAGRPPKPDLAIEAAvgsLVREAIAQGLLASAHDCSDGGLAVALAESCIASDLGISV--------------------------------------------------------------------------------------------
>UniRef50_D1Z279(31-331:334) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Methanocella paludicola SANAE RepID=D1Z279_METPS  E=2e-34 s/c=0.49 id=19% cov=67%
--------------------------------------------------------------------------------VNDLYVMGVEPLAFVDYVSIEKP-DDELIRQVMVGLDEGARQANISIVGGETAALPD-IIKGFDLAGTAVGYVGKDKVVTGEGIAPGDVVIGLPSSGIHSNGYSLVRKvveksglkytdplPYDKKKTIGAELLTPTRIYAEvvpIFRKYPVKGMAHITGGGLM-NLRRI-TGYGFEFNDPLPVPPVFTWLQKLGGIDDEEMYKTFNMGmGYVIITDKESAGAIVKM-------TDGKIVGRIVKE-GCTVRGT-------------------
>UniRef50_C7QYT6(14-316:355) Thiamine-monophosphate kinase n=1 Tax=Jonesia denitrificans DSM 20603 RepID=C7QYT6_JONDD  E=3e-34 s/c=0.49 id=21% cov=33%
---------------SQIIDRIqrFLCGTVHTEVGVGDDAAVVRA-----PDGRVVVSTDALVEGHHFRREWssarDVGWRAGTQNLADIVAMGASPTSMVVALGVPRDTPVQWVMDFYDGLSQVCATVGAEIVGGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_P49903(28-371:392) Selenide, water dikinase 1 n=64 Tax=Metazoa RepID=SPS1_HUMAN   E=3e-34 s/c=0.43 id=20% cov=84%
-----------------------------PRLGIGMDTCVIP---LRHGGLSLVQTTD--YIYPIVDDPYMMGRIACANVLSDLYAMGVTeCDNMLMLLGVSNKMTDRERDKvmplIIQGFKDAAEEAGTSVTGGQTVLNP-----WIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGtqvavavhqwldipEKWNKIKLVVTQEDVELAYQEAmmnMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACG-NMFGLmhgtcpETSGGLLICLPREQAARFCAEIKSPKYGEghQAWIIGIVEKGNR--------TARIIDKPR--------
>UniRef50_Q58MH8(59-330:331) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Prochlorococcus phage P-SSM2 RepID=Q58MH8_BPPRM  E=7e-34 s/c=0.54 id=19% cov=67%
--------------------------------------------------------------------------------VNDIITCGAKPLYFLDYIS-TQKLD-DKIPDIMTGIIKGCEIAGMDLLGGETAEHPQYQM-KIDLAGFCTGIVEKKKIIDGSVIKPSDRIIGLASSGVHSNGYSIinylarrLKLGYYSHPELLTPTTIYAPVVERLLnEVEEVYGMSHITGGGIPENLPRCLPK-GLKAHVDWNAWSVPEIFLEIqrqGNMDELEMRRVFNLGiGYCVIVPANRAELTMDIIRGE--GIECWEIGEVYEDK--------------------------
>UniRef50_A8FAM7(67-374:743) Phosphoribosylformylglycinamidine synthase 2 n=93 Tax=Firmicutes RepID=PURL_BACP2  E=1e-33 s/c=0.47 id=20% cov=69%
----------------------------------------------------------------------------VGGIIRDVFSMGARPIAVLNSLRFGELTSPRVkylFEEVVAGIAGYGNCIGIPTVGGEVHFDQSYEGNPL-VNAMCVGLINHEDIKKGQAKGVGNTVMYvgakTGRDGIHGATFAseefSDESEEKRSAVQVGDPFMEKLLLEACLEvikNDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLIPQRE-----TGMSAYEMMLSESQERMLLVIEKGREQEIIDIFEKYDL--EAVSVGHVTDDKMLRL----------------------
>UniRef50_A7X0W1(423-703:729) Phosphoribosylformylglycinamidine synthase 2 n=61 Tax=Staphylococcus RepID=PURL_STAA1  E=5e-17 s/c=0.32 id=16% cov=66%
------------------------------------------------------------------------GKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIdstKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTpvVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGsqlekLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQ--------------LFSETQGRYVVSVKSGKTLNI----------DNAIEIGLLTDSDNFKVTTPY------------------
>UniRef50_B8EBM9(10-338:352) Selenide, water dikinase n=223 Tax=Bacteria RepID=SELD_SHEB2   E=1e-33 s/c=0.44 id=21% cov=73%
-ESIKLteySHGAgcGCKISPKVLSTILasqLPVFTDPNLLVGNQSRDDAAVYKLNDDIGIISTTDFFM--PIVDDPFTFGRIAATNAISDIYAMGGTPIMAIAILGWPiNKLPAEVAQQVVDGGRQACMEAGIMLAGGHSIDAP-----EPIFGLAVTGQIALTDLKQNDTAKAGDRLYLTKPIGIGILTTAQKQKKLQDEDSHIAVNAMcqLNTIGTTIAKISGVNALTDVTGFGLAGHLLEMCQGTKLTAKLKFDAVPL-------------------------------------------------------------------------------------
>UniRef50_Q02AU6(8-290:304) Thiamine-monophosphate kinase n=1 Tax=Candidatus Solibacter usitatus Ellin6076 RepID=Q02AU6_SOLUE  E=2e-33 s/c=0.51 id=20% cov=66%
---------------AELIAQIRGRITPAPGvvLGIGDDCAIVR---PRGSAEDWLYTTDLLIEGTHFLRathtAADVGWKALARGLSDIAAMGGTPRFCLLSLALGDWVDARWVDGFYRGLLRLAGRSGATLIGGDVARTAHVTCD-----IVVAGTVARGKALRRDRARAGDAIYVSGALGGSAHGFATESGKAW------SRHKRPEPRLALgrfLREQVGATAAMDLSD-GLSLDLRRMCLASRVRAEI--TAPPVFPG----------------------------------------------------------------------------------
>UniRef50_D2RFS1(92-393:761) Phosphoribosylformylglycinamidine synthase II n=4 Tax=Archaea RepID=D2RFS1_ARCPR  E=3e-33 s/c=0.48 id=21% cov=68%
------------------------------------------------------------------------------GILRDVLCMGAQPIALVDPLFfgnldikdLPKGVkhPLYLLFGVVAGIRDYGNRVGIPTVGGMVFFDESYVTNCL-VNVGCVGIVRKDRIVHSRVGNVGDLFVLvggaTGRDGIHGVTFASKELSEKSEEERGAvqlgnpiMKEPLIHACLEVVEKGLVTGMKDLGGGGLSCVISEMSYAANCGAEVYLDKVHLKEEGMAPWEI-----YISESQERMMLTVNPKHVDEVLDVFKK--WDVPAVVVGKAIPDKVVRV----------------------
>UniRef50_D2RFS1(470-738:761) Phosphoribosylformylglycinamidine synthase II n=4 Tax=Archaea RepID=D2RFS1_ARCPR  E=1e-18 s/c=0.36 id=24% cov=26%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYACHDLAEGGLAVALAEMC-IGGFGCKVDLSELRGEDYVK----------LFSESNTRWLVEV--DNAEDFVKFMKS--KGLSVYAIG-VVEGDEIVVKN--------------------
>UniRef50_B8D469(6-317:340) AIR synthase related protein domain protein n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D469_DESK1  E=4e-33 s/c=0.46 id=20% cov=90%
--------GSLGEMGEEAVINLIADKLISKPESGESLTYPDDARDLLPKGPRLIYSMDAYRIKSLMLPwrtWSDIGWMALTGALSDVVVKGGVPSVAMIGLGLSSETDILDLEELVKGLREASNYYDVRITGGDT-----NESLDPWIAVSVMGFTTCKRPPSRRGARPGDIVIATGSYGSMGFVALHGVVEASGISWVVDNTKRVYLKLEvanVIMSTYRFIHASMDVSDGLGYTLEQLSELSGYGILL-ENLPVHPAGLREYCKNSIECMWRhvlvGGEEYGAVLIVAGEYLDKVAEELDYYE--IPYSIIGRVGNiSPGIYINGA-------------------
>UniRef50_A8MCK2(393-714:724) Phosphoribosylformylglycinamidine synthase 2 n=1 Tax=Caldivirga maquilingensis IC-167 RepID=PURL_CALMQ  E=1e-11 s/c=0.23 id=18% cov=71%
-----------------------------------------------------------------------------------VASVGAKPIAAVDSINVgnPEKPDKYWyFVKTVEGLTWMGNALGIPFVGGKVSFYNEDSVTGASIKPVVAVAVLGVVNDYAKAIEGGLtgegWLVIIGDTGpeLGGSEFLHSVHGLVAGEPPEPKPLSEVKnanLVMQLINNGLAKAVMDVGVGGLAAALIKMSIIGGVGFTVDLSKAPLTQGLN--------DPVTVaFSETNARYIIETSNLKETVRIIEAN--GVPYGVLGE---SGGGIVQFKWGGLELASLSVDDLV----
>UniRef50_Q8TX80(19-327:327) Selenophosphate synthetase n=1 Tax=Methanopyrus kandleri RepID=Q8TX80_METKA  E=5e-33 s/c=0.47 id=22% cov=73%
------------------------------------------------------------------------GYCAVLVNVNDVLAMGGRPVGLVNVLSTS---DVDVCREILEGMREGAWKFSTPVLGGHTHPDTPYTA----VDAAIVGVTDEEHLVLSSTAEEGDLIVFVIDL----NGRPYPEYPLNWDTTTMKDPDYLRRQMEAVVEASKlVKAGKDVSNPGLVGTLAMMLEASGClGAEVWLDSIPKPEDVDMVT------WLKMYPGMGFVYAVDSErDVRAIRRVLSDARL--EVSVIGEVTEDGVVKVSEGDESARVFDFREDRILgvsPR--
>UniRef50_Q97CD7(15-327:338) Phosphoribosylformylglycinamidine cyclo-ligase n=4 Tax=Thermoplasmatales RepID=PUR5_THEVO  E=5e-33 s/c=0.46 id=19% cov=87%
-----------GEFVSSFIRQLKFHREDFKNIGY----IGGFTSLIDMGNFALSFNNDGVGTKTMIAEQANkydtLGIDCVAMNVNDAITVGSEPIAMVDYLAV-RDLNEDIAKQLGNGFNVGAQIANISIVGGETAVVPE-IVNHIDVSGAVIGIVQKNQIITGANIKEGDVIIGLGSSGLHSNGFTTVRkiisdneinlfdnfpgESKKTYEVLLEPTRIYVREILDVMGIIQIKGMANITGGGFKNITRM--KDMKYVIDDPMEPQNVFVRLMELGNLNYKQMYEIFNMGtGFVVVIGEDDKIDFINTLKNR---VPLKVIGHVENGTGV------------------------
>UniRef50_C1CVZ1(57-348:361) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Deinococci RepID=C1CVZ1_DEIDV  E=7e-33 s/c=0.49 id=24% cov=68%
--------------------------------------------------------------------------------VNDILVQGARPLFFLDYVAM-GRLKPEAVAEVVTGAAQACEALGVALLGGETAEMPGVYVEGeLDIVGTIVGVVDRPRLVDGQRIEVGDSVIALPSSGLHTNGFSLARMALdgldwdearsDLGGQSLAEVLPVPHRsylqAHAALESAGVdiRGMAHITGGGLVDNPPRVFPA-GIGMRVDTSSWSVPPLFELIvreAQVERLEAFRALNMGvGFLFIVPAAQREQALRVLASA--GEQPWVIGEMIAGQGV------------------------
>UniRef50_A0QAT1(76-388:765) Phosphoribosylformylglycinamidine synthase 2 n=34 Tax=Bacteria RepID=PURL_MYCA1  E=1e-32 s/c=0.46 id=20% cov=72%
----------------------------------------------------------------------------VGGIVRDIMAMGARPVAVMDQLrfgAADAPDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDACYAGNPL-VNAMCVGVLRQEDLHLAFASGAGNKIILFGArtglDGIGGVSVLasdtfdAENSRKKLPSVQVGDPFMEKVLIECCLELyagGLVIGIQDLGGAGLACATSELASAGDGGMEVRLEAVPLR-----TAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRK--WDVLATVIGEVTDGDRLRI--TWHGQTVVDVP---------
>UniRef50_D1B9P1(43-343:709) Phosphoribosylformylglycinamidine synthase II n=4 Tax=Synergistaceae RepID=D1B9P1_THEAS  E=1e-32 s/c=0.48 id=19% cov=67%
----------------------------------------------------------------------------VGGIIRDILAMGARPIMSMDGLFFGDSDSPKakhIREKVVEGIGGYGNAVGVPTVGGLTIYDPCYE-DNPLVNAFCAGVVELDRLCSSKTARPGMRVVVlgarTGRDGIAGASFAsteLKDHGASNKPQIQiGDPFYEKLLIEACLELlnqGVIQAMQDMGAAGLLSSSSEVAHKSGNGIDIHCDRIPLRE------EMEPWEIFLSESQERMLIICLPEDLPRLSAT--AEKWGLEWADVGEITD----------------------------
>UniRef50_C1SLQ6(14-325:325) Selenium donor protein n=1 Tax=Denitrovibrio acetiphilus DSM 12809 RepID=C1SLQ6_9BACT  E=1e-32 s/c=0.46 id=18% cov=81%
--------------------KLFRPDQLLVGFETGDDAGVFDMG----NGLYLVQTVDFIT--PVVDDAYDFGRISALNSMSDVYAMGGTPVTALSVLLYNCSIGGEIIKTMLQGAADEFAKAGCALAGGHTVYDP-----EIKLGFSITGKITNGKIYKNVGLREGDILIYTKPLGIGliSTALKAQMASPEDIKAVTDTMLMSNAAASEIMKKYDVSACTDVTGFSLAGHSYEMASGSGVTIEIDSRATYTIEGAFRYAKDFIipagaysnmeflkgrcefetkpdnahmvfFDPQTS---GGLLIGVSETDSNKLLGEL--LENGIPAQQIAYAT-----------------------------
>UniRef50_B9K5N4(20-309:328) Selenophosphate synthetase-related protein n=3 Tax=Alphaproteobacteria RepID=B9K5N4_AGRVS  E=1e-32 s/c=0.49 id=21% cov=86%
---------SGGIAAKHDIGSVTARL----GVKGKSVAVGDDCAALPEGDGYLLFAIEGFMNAFVAADPWFAGWCGVMVNISDVVAMGGRPTAVVDAVWADG---EADAAPVLDGMRAAAEAYGVPIVGGHTNI----RTDRSQLSVAILGRAK--RLLTSFDARPGDVLVAAVDHrGRYRPPFDNWEAATDAPAERLRGDLEILPQI---AEAGLALAAKDISQGGIVGTAIMLAECSGVGIDINVAAIPLPEDV------SLDRWLATFPSFGYLLSVPPEHVTAVLTRFETRD--ITAAIIGTVSVGSAVAITN--GSKRIV------------
>UniRef50_B2UNI3(15-329:333) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Verrucomicrobiaceae RepID=B2UNI3_AKKM8  E=2e-32 s/c=0.45 id=19% cov=70%
------------------------------------------------------------------------GKDLVAMNVNDILTTGGDPLLFLDYLGISNlERERSRITRLVAGMCDYLESCNCILAGGETAEMPGVVPESIVeLSGFCIGCCEKSKLIDPKTVQPGDVFIGYKSDSFHANGWSLIRRILEenpdvvDEEELRSLLQPtrlYHDVVEDMRRFNVTpKAYAHITGGGLPENLERFLGDYGADLSIPYWDNT--AAQKILKHVDPQDRFNTFNMGiGWVAIVRPEDAEAALKA------GPGGTVIGTLREGRGIHVK---------------------
>UniRef50_Q5HSQ7(15-329:329) Phosphoribosylformylglycinamidine cyclo-ligase n=23 Tax=Campylobacterales RepID=Q5HSQ7_CAMJR  E=4e-32 s/c=0.45 id=24% cov=70%
-----------------------------------------------------------------------IGQDLVAMCVNDLICNFATPLFFLDYYA-TAKLEVEVAKAVVSGIAKGCKMANCALIGGETAEMPGmYAKDDFDLAGFAVGMAEEDEIDRSKFVKNGDILLALPSSGLHSNGYSLARKVLFESLKLKFDDKIEDKnLIDILLEptriyvrdfltlKPYISALAHITGGGLVENLPRVLPR-GMGATIRKHHLKTPEIFYIIGQAVEEsEMYRSFNMGvGLVMVVDPSNVSKVLE-------NSDAFIIGEICINEGIVLE---------------------
>UniRef50_C5EK55(2-299:305) Selenide n=1 Tax=Clostridiales bacterium 1_7_47FAA RepID=C5EK55_9FIRM  E=4e-32 s/c=0.47 id=25% cov=67%
------------------------------------------------------------------------GLIAAANSLSDVWAMGGEPRLCMNILMFPDSLPPEAVNAILRGGFDKVAEAGAILVGGHTLKD-----DIPKYGLCVSGLVPPNRILRNNTVREGDVLILTKPLG-TGILTTADRGGLLTRAEHQAMVRSMTTLnkyaADAVRSLDGIHACTDVTGFSLLGHSFEMCAGTGLTAVIDSARVPLLPGADTYASMglvpaaayqnmghlkekvslpgslashihdLLFDPQTS---GGLLYSVARGEAGRIMEAILKAC--PEATVIGHV------------------------------
>UniRef50_A1R7J3(68-350:391) Thiamine-monophosphate kinase n=7 Tax=Actinomycetales RepID=A1R7J3_ARTAT  E=7e-32 s/c=0.49 id=26% cov=59%
---------------SELLARIFPRLHHSPGvlLGPGDDAALISA-----PDGRTLISIDTQTQDQDFrlewrngyrTTGYDVGWKAAAQNLSDINAMGGSATSLVVSLTMPPETPVEWVEAFADGLSAAivgLGARDCSVAGGDL-----GRGRELAVTVAVVGTLAGMAPVLRSGAKPGDVVAVSGTLGRAAAGWALLESEIPLDslsGELRSlvdnQCRPLPPLAAgPLAAHAGATAMLD-------------------------------------------------------------------------------------------------------------------
>UniRef50_A3TRA0(13-334:346) Thiamine monophosphate kinase n=1 Tax=Janibacter sp. HTCC2649 RepID=A3TRA0_9MICO  E=8e-32 s/c=0.43 id=21% cov=84%
---------------SDLLARIIPMFGESPFAGSGVLVAPGDDAAVITARESVVVTTDSMVRGRDWRDDWssghDVGLKVVAQNVADVAAMGAVATGLLVSVAADPETELDWVIDLTRGIADAAEDAGCPVVGGDLSSAPAGV---VLVAVTAFGDLQGRMPVLRSGARPGDVVAVAGSLGWSGAGLALYEAGtpdpiapdagaghltarERATSVLMWFHRSPRPPWEsgPVAADAGATSMIDLSD-GLVRDGGRIAVASGVELALDEAQLREHflagPIELAVGEDVGWrQVLSGGEEHSLLATFPADAVPD--------DPHAPWTVIGQVVE----------------------------
>UniRef50_B5IM46(21-317:328) Selenophosphate synthetase n=7 Tax=Chroococcales RepID=B5IM46_9CHRO   E=8e-32 s/c=0.47 id=20% cov=88%
-----------GKEEIQLPAGMF-PQLPFPGLGPAA-AIGDDAALIPASSGPLLLASEGMDPALVEEDPWFAGWCGVLVNLSDIAAMGGRPIALVNSLWASGETQ---ARPLLAGLRRAADTFAVPMVGGHTNLHSPYNA----LAVAVLGTAPGP-VLSARAARPGDRLhLLVNTQGR------LYRHYPFWDAATQAEPAMLRRHLAlpvELAAAGLVRAAKDISMGGLVGTAEMFAEAAGCGLEIQLD------ELQPPAGLSLEAWLTCFPSFGFLLAVPPERTAE-LARFTAPHPELLCAEIGRFLAGAPQVLLAAGAGRCPLRPP---------
>UniRef50_B5ICX6(26-265:302) Thiamine-monophosphate kinase n=2 Tax=Aciduliprofundum boonei T469 RepID=B5ICX6_9EURY  E=1e-31 s/c=0.58 id=16% cov=28%
--------------------------------------------------------------------------------LSDIAAMGGEPEIFMASMFFPKRMDLGFLEDFMKGMLEILNDFNVPYKGGDLKESRI-----IGFSGIAIGKVEKERIMLRNAINKGEGVYITGELG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A3EVN2(52-361:737) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Leptospirillum sp. Group II RepID=A3EVN2_9BACT  E=2e-31 s/c=0.45 id=20% cov=68%
----------------------------------------------------------------------------VGGILRDVIAMGARPVALANSLVFGSlrhPKHRTLFQRVVEGIAGYGNPAGIPTVGGEIWFDDRYQHN-ILVNVMAVGIVNNNEIMSAKASQKGLLAIYignrTGRDGVSGAAMAS-RGFSKDGADLRPQVQIADPYAgknlmeatLEIARKKLADSIQDMGAAGLTSSSTEMAGRAGLGMELDVSCVPLRDKTMEPWEI-----LLSESQERMLVLSCPENAEKILDIARA--WHLSAAIVGRTIQEPNFVV----------------------
>UniRef50_A1VP32(55-318:341) AIR synthase related protein n=13 Tax=cellular organisms RepID=A1VP32_POLNA  E=2e-31 s/c=0.52 id=23% cov=56%
--------------------------------------------------------------------------------------------------------------QVMVGMAEASRRYGVPIVGGHTNHRSDHGQ----LAVAILGRARK--LLTSFDALPGHRLLMAIDLrGAYQEPNPYWDASTSAPAERLRADLELLPI---LAEDGLCNAAKDISMAGAVGTALMLLECSEVGAMIDIEAIPRPLGV------PLLRWLQSFPSFGFVLSVRPEVADEVVARFHAR--GIACADVGEVSAAPQVWLR---------------------
>UniRef50_O62461(32-355:378) Probable selenide, water dikinase n=3 Tax=Chromadorea RepID=SELD_CAEEL  E=2e-31 s/c=0.43 id=19% cov=80%
-------------------------------INNDEVDIGLDSCVIPLrhPGLRLVQTTDFFY--PLIDDPYIMGRVTCANVLSDLYAMGVsECDNMLMLLAVAIDLNEKqrdiVVPLFIQGFKDAADEAGTKIRGGQTVRCP-----WLLLGGVATSVAHESEIIKVDQAVPGDVLILTKPIGgqVAVNSYEWIKKKNGKIEELnleipkiekafkqvCEQMSRLNRNAAKLLHKYDAHSSTDVTGFGLLGHAENLARVQKQPMEFIIEKLPIIEYMDEIADKMiakggeGFKLYQGtsaETSGGLLIAMSEENAKKYIAELSSLD-NAPAWIIGKVT-----------------------------
>UniRef50_Q58057(39-315:324) Uncharacterized protein MJ0640 n=8 Tax=Euryarchaeota RepID=Y640_METJA  E=2e-30 s/c=0.49 id=12% cov=46%
------------------------------------------------------------------------------------------------------------------------------------------------------GIAKKDCILRSDNAKIGDKIIFAYDL----VGQIYKSFPLNWDTTTMKSKKLVRAQMDALvqiAENKLANSCKDISNPGAIGTLGMLLEVSRKGGVVDITKIPKPE------EIDLIHWLKVYPGSGYVLTAKEENFKEIKDIFEDVEM--TAEICGEVIAEKKLYI----------------------
>UniRef50_A0QV00(34-325:337) Thiamine-monophosphate kinase n=9 Tax=Corynebacterineae RepID=A0QV00_MYCS2  E=2e-30 s/c=0.46 id=28% cov=40%
-----------------------------------------DAAVIATSDGRTAVSTDMLVERRHFrldwASPHQIGRKAIAQNAADIEAMGARPAAFVVSFGAPSDTPADAAVELSDGMWDEARRCGGGIAGGDLVRAPL-----WVISVTVLGDLGGRAPVLRSGARAGDVVAVAGDLGRSAA-----------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B5YF26(41-327:712) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Dictyoglomus RepID=B5YF26_DICT6  E=4e-30 s/c=0.47 id=17% cov=80%
------------KHSRKYLKD-FLTKAEWVEQGPGENAGIINLG----DGYRVVFKIESHN-HPSAVEPFQGAATGVGGIVRDILAIGARPIALLDSLRFgpiEKGRNKYLFEGVVGGISFYGNCIGVPVVGGEIVFEDCYSSNPL-VNVMCVGLLGPEQKSYRGKAEgKGNLLLLvgarTGRDGLQGASFASEKLDDEVhkkrPSVQVGDPFLGKLLIESCLEAAstdGVVGIQDLGAAGLVSSLSESARRGRSGVKVYLDKVPQREE-----NMTAEEILLSESQERMLLVIRPEKAEEIISIFKK-------------------------------------------
>UniRef50_Q9RXT4(47-366:747) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Deinococci RepID=PURL_DEIRA  E=6e-30 s/c=0.42 id=18% cov=73%
----------------------------------------------------------------------------VGGILRDIFAMGARPFAVLDSLRFGNPDSPRtrfLVNGVVDGIAHYGNAIGVPTVGGEVTFHPSYQENPL-VNVMALGLLRHEDLATGTMGEVGNQIVYVGSktgrDGLGGAVFSSADlsaaSQADRPAVQVGDPFMEKLLLEATLEaiqAGLVAGVQDMGAAGLVSSTCEMAYRASLGITMDLDKVPTREE-----GMVPMELCLSESQERMILVPVPGKEQALHDLLAKWEL--DVVTIGEVEAHDRYRL--TWKGEVVCDLPVA-------
>UniRef50_B5Y8K3(3-304:310) Hydrogenase expression/formation protein HypE, putative n=1 Tax=Coprothermobacter proteolyticus DSM 5265 RepID=B5Y8K3_COPPD  E=7e-30 s/c=0.44 id=19% cov=76%
-----------GKVPVSYIGDLVERFYGKRRQEVLIDASNLTDSAVVDLDAPMVVSTDPIT----GADNHVVTQLAVHINANDVRVAGGEPVAFLAVLLLPTNFPQKDIEGMFEHLHEGLDYENAQLVGGHSEF--TSAVTKPVVVGTMFG--KRIRVLGKDLVRPGQHVFFAGTLGREAMMILRGSYGDDILKV------SVKPIMDVALNVPSLVFAHDLTEGGLVAGLWELTRGTSLGIEASFPESYLDQELIQLSRRFQFNPYKIISSGSVLLVC---------------------------------------------------------
>UniRef50_A7GYY9(480-713:729) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Proteobacteria RepID=PURL_CAMC5  E=1e-12 s/c=0.33 id=18% cov=48%
-----------------------------------------------------------------------------------VAMSGAMPLAITDCLNYGNPQNPEVMWQFAQgceGIKEACRELNTPVVSGNVSLYNDTDGVSVYPTPAIvsVGVNDDARAnLKSVFGSAGTAIYLLGETKGEFAASLYVKALFDVVGGTLSEIdykkeRALWELVIAANKAGVLEFANSVGVGGVAMSLAKMACISGIGAE---------------------------------------------------------------------------------------------
>UniRef50_D2L8W8(45-308:322) AIR synthase related protein n=1 Tax=Desulfovibrio sp. FW1012B RepID=D2L8W8_9DELT  E=3e-29 s/c=0.50 id=19% cov=66%
------------------------------------------------------------------------GRCAVLANINDIYAMGGRPLAMVDVVGTP---DEATAREICRGMRDAAARYRVPVVGGHLLRTAFDHSA----SMAILGRAKT--CLTSFDARPGDSLVLaTRPNGAWLGDLGFWNATLPEDDATLIAHLELLP---ACAEAGLARAGKDVSMAGLAGTALMLAESSGVGCRLDVDALSPPPG------APLTPWLLAFMSYGFLLAVAPDKLDAVVALFTA--GGVRTVPVGEVCRERQVWL----------------------
>UniRef50_D1B9U1(11-342:344) Selenide, water dikinase n=3 Tax=Synergistaceae RepID=D1B9U1_THEAS   E=1e-28 s/c=0.39 id=18% cov=82%
----------------------------DPNLLSGWDN-GEDAALWRIGEGRLAIlTVDFIT--PIVDDPLTFGEIAAANSLSDVFAMGGSPKVALNLVAFPTSCEPlEVLSQILEGGARKVMEAGACLAGGHSVQDE-----EPKYGLSVYGEVDEGGLWRVTGAREGDSLILTKPVGSGIITTASKggVAEGDWLDQAVQWMRMLNNVPGRMDRslLGNVRAATDVTGFGLLGHCMDMLSHRELDLVIHHDQVPFIDGAFQMASMgmvpagaysnrghvehrvlmspnvplavqdILFDPQTS---GGLLLAVAPGSEKEVLSQLWELGFHRAATV-GRFIKGEGKVL----------------------
>UniRef50_Q72LK3(29-301:311) Thiamin-monophosphate kinase n=2 Tax=Thermus thermophilus RepID=Q72LK3_THET2  E=2e-28 s/c=0.47 id=24% cov=68%
----------------------------------------------------------------------------VAATASDLLVKMGRPLGFTLGLFLPEDLEEGFVLELVRGAAEAAKRLGAFLLGGDTNR-------GVEVALTVSGYALAEAPLPRKAL-PGDLLYLAGDrWGRTGAAIRAHYEGRSLEGfpKIREAAFYPLPRLELLALSGLLRGSLD-SSDGLAETLWQL---SELGVRVELEVLPLYPDVLAFAgseEAALELVLYGGEEFEAVLVVPQEGAA--AVEARAKAKGLPLFRVGRVVAGEGVYLRGA-------------------
>UniRef50_C9SUR7(433-744:759) Phosphoribosylamine-glycine ligase n=1 Tax=Verticillium albo-atrum VaMs.102 RepID=C9SUR7_VERA1  E=2e-28 s/c=0.41 id=22% cov=68%
--------------------------------------------------------------------------------VNDLVVQGARPLMFLDYYGCSK-LDLSTAASFVEGVAAGCIDAGCTLVGGETAEMPGmYQKDDYDAAGCAVGVMTGRHRLPRtQDMAQGDVLLGLASSGVHSNGFSLVRKIVEREglqysdqapwdqgrsvgENLLTPTRIYVKSLRGVVEKGLVKGLAHITGGGLIDNVPRMLPD-ELAAEIDLTSWQVPAVFKWLkisGNVEALQMCRTFNMGiGMVVAVGVDQIQDTVAALEAA--GEQVSRIGRLVKRDG-------------------------
>UniRef50_B3E0M2(435-742:762) Phosphoribosylformylglycinamidinesynthase, synthetase domain n=1 Tax=Methylacidiphilum infernorum V4 RepID=B3E0M2_METI4  E=8e-22 s/c=0.34 id=19% cov=69%
--------------------------------------------------------------------------MAVAEAMRNLAVVGAIPLGITDNLNFadpNDPFSYWQFKEAVRGIAEACRFFEIPVTGGNVSFYNFSKQSSILPTpvIGAVGLIETDKALAKMAFQnPGDVIVLLGGWGNGLEGSLYLQEYFGESGQKLPHFSLEaekkhNELLYSLANEGIASSIHDLSEGGLGLALVECSVSGDKKLGF---------SISLPAELRLDELLFNEAGARSVVSLPGENLSSLLKI--AEGKGVQGIVLGEVTEEYFLKLR---------------------
>UniRef50_P00967(799-1126:1353) Phosphoribosylglycinamide formyltransferase n=19 Tax=cellular organisms RepID=PUR2_DROME  E=7e-28 s/c=0.38 id=23% cov=67%
--------------------------------------------------------------------------------VNDILCNGAEPISFSSYYAC-GHWQEQLAKGVHSGVQEGARQANSSFIDSHSAALPLLYEPQVYdLAGFALGIAEHTGILPLLAeIQPGDVLIGLPSSGVHSNGFSlvhavLKRVGLGlhdkapfsdktLGEELLVPTKIYVKALSTLLSRGkhGIKALAHITGGGLSENIPRVLRK-DLAVRLDANKFQLPPVFAWLAAAGNIsstELQRTYNCGlGMVLVVAPTEVEDVLKELR---YPQRAAVVGEVVARK--------------------------
>UniRef50_Q4JXF0(432-774:813) Phosphoribosylformylglycinamidine synthase 2 n=100 Tax=root RepID=PURL_CORJK  E=1e-16 s/c=0.26 id=17% cov=68%
--------------SREFITEQYDRYVRGNTVAAKDADAGV-LRIDEETGRGIAVSTDASGRYAR-LDPRTGAQLALAEAYRNVSVTGATPVAVSNCLNFGSPEDPGVMWQFreaVHGLADGCKEMGIPVTGGNVSFYNQTGDTAILPTpvIAVLGTIDdcarriPQQLPKQAGAEAGADesqeqyhLVLVGAETREELGGSIWQQvvHDELAGLPPQVDLSVEQRLGAFItdQRDKIVAAHDLSEGGLSQAVVELAIQSGRGMAV--------------------------------------------------------------------------------------------
>UniRef50_C7NGL3(19-320:327) Thiamine-monophosphate kinase n=1 Tax=Kytococcus sedentarius DSM 20547 RepID=C7NGL3_KYTSD  E=3e-27 s/c=0.41 id=24% cov=52%
----------------------------------------------------------------------------------DVTAMGGRCTSMVLTLVADAHTPVAWVEELAVGVGERAREAGVAVTGGDLSSAPAGTR---MVSITALGSLDGP-PVLRSGARAGDQLAVSGPLGRSAAGLALLQAGRtqaepgTAAAECLEHHRAPRvdPGAGQLAAAAGATAMLDVSD-GLGRDGARLATASGVALLLDREA--LGGDVRRAWEALG-------------------------------------------------------------------------
>UniRef50_Q5HSS7(16-330:340) Selenide, water dikinase n=16 Tax=Campylobacter RepID=SELD_CAMJR   E=1e-26 s/c=0.39 id=18% cov=58%
--------------------------------------------------------------------------------------------------------DVNILKELLEGANDKVQECNALVVGGHTIEST-----ELFFGLSVTGKVHPSKFIANNTSKIGDCIILTKPLGTGILSTALKAQMLNqkhLDIMLKNMM-ELNYKASQIALKFHPSAMSDVTGFGLLGHLKEMlnknisfeifqneilflegAKEYFNMGLIPAGAYKNLEFIKELIPDLNEEKLLLCDpqtSGGLLISISEKESLECLKKL--EDENIQAKIIAKVV-----------------------------
>UniRef50_B7AVF9(38-301:305) Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus ATCC 43243 RepID=B7AVF9_9BACE  E=4e-26 s/c=0.46 id=22% cov=73%
------------------------------------------------------------------------GRYAVIDACNALACRGGEPEGINAAVTIPDSYDEKLLKKLIADIDAQCRTCGTHI--EDVAVSTSQHIRKPVITASAFGRSSEEMPAGMQKAGGNLDIIASGSIGMSGIMNVLDSHMDEAKKVYADS------VINAAAADAGKLSVADraslaagagasylvaAGDGGIYAALWRLAADNGCGFDINLRDIPVKQEIIEMCELFDINPYELSSTGCMLMTA--EDGCGIVDVL--NENGYDAVVIGHTTKEKAKMMHLEDEV-RYLDVPRNE------
>UniRef50_A8SRC0(84-342:344) Putative uncharacterized protein n=1 Tax=Coprococcus eutactus ATCC 27759 RepID=A8SRC0_9FIRM  E=2e-25 s/c=0.46 id=23% cov=63%
-------------------------------------------------------------------------------------------------------------KKLLGKLAGICAECGVDIITGHTEVN--TAVFEPIISVTMMGKQsghSDDADLCRLKRPVGMDIVMCGQTGVGGTLQLYYDNQKELFERYSESYLRPVERMEELILLGrqvdialehGSVYAHDISRGGVFAALWEMGDALKCGLEVCHDDIPILQETIEICEHTGDNPYMIDGCGAALFVVP--DGEHLADKL--YEAGYEASVIGHLTENSDRVVVH-DEERRFLTPPR--------
>UniRef50_C8V0S2(487-801:809) Phosphoribosylamine-glycine ligase (Eurofung) n=27 Tax=Saccharomyceta RepID=C8V0S2_EMENI  E=5e-25 s/c=0.37 id=32% cov=29%
--------------------------------------------------------------------------------VNDLVVQGAEPLFFLDCYSC-GKLDVETAAAFVTGVADGCIQAGCALIGGETAEMPGLFIDDTYDAVgAAVGAINtsgpnaRTILPDTSSMKAGDVLLALASSGPH-------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C1TMB6(1-275:278) Selenium donor protein n=1 Tax=Dethiosulfovibrio peptidovorans DSM 11002 RepID=C1TMB6_9BACT  E=5e-25 s/c=0.43 id=17% cov=48%
------------------------------------------------------------------------------------------------------------------------------------------------------GEVEKDALWKTTGADPGDLLILTKPLGSGIIATAVKADMVDdpvWAEDATKWMSKLNDLPLKMARsmRKAIKSCTDVTGFGLAGHCLDMLSTKKVNLELKSEKLPLMDGALELASMgllpagaytnrslyegrvegldsmgeradFLFDPQTS---GGLLLTVSPDKSEELMELAIENGFEKTA-VIGRFKDGDGRI-----------------------
>UniRef50_A3V944(395-698:698) Selenide, water dikinase, putative n=3 Tax=Rhodobacteraceae RepID=A3V944_9RHOB  E=7e-25 s/c=0.38 id=23% cov=82%
--------GCGAKVGRAALQQVLGDAF-------GDDAGLVQTGQ--------VITTDhlrALVADPVLMT-----RIAAIHALGDIWAMGATPQAATVQIILPRmesALQQRTMAEITATTTAVMSEAGARIAGGHSAL-----GDELTIGFTITGLV--DRPITQAGARAGDALILTKPIG-SGTIMAGDMAGQARGADVIACLdLMVQSQAKAAAILHAAHAMTDVTGFGLLGHLRGICDASGTGAVLDWAQVPVMAGaavlsargvrstlfadnqagagvVEGAVPDLAYDPQTA---GGLLAAVAGHSADDLLGALTRA--GYTAAIIGQITDGSAISLR---------------------
>UniRef50_C0W2R7(16-340:370) Thiamine monophosphate kinase n=1 Tax=Actinomyces urogenitalis DSM 15434 RepID=C0W2R7_9ACTO  E=8e-25 s/c=0.36 id=26% cov=27%
----------------------------------------------------------------------------------DAAAMGARPVALVVSLVLPGDTPVSWMEGLARGLGEECRKAGAGVVGGDLS-----AGESIVIAVTVHGDLEGREPVLRSGARAGDLVVHAGDLG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q5T5U9(28-300:321) Selenophosphate synthetase 1 n=2 Tax=Eutheria RepID=Q5T5U9_HUMAN   E=2e-24 s/c=0.42 id=19% cov=69%
-----------------------------PRLGIGMDTCVIP---LRHGGLSLVQTTD--YIYPIVDDPYMMGRIACANVLSDLYAMGVTeCDNMLMLLGVSNKMTDRERDKvmplIIQGFKDAAEEAGTSVTGGQTVLNP-----WIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQ-----------------------------------------------VAVAVHQWLDIPEKWNKIKL--VVTQEDVELAYQEAMMNMARLNRTGGLLICLPREQAARFCAEIKSPKYGEghQAWIIGIVEKGNR--------TARIIDKPR--------
>UniRef50_A5UWJ5(285-583:985) Phosphoribosylformylglycinamidine synthase II n=6 Tax=Chloroflexi (class) RepID=A5UWJ5_ROSS1  E=2e-24 s/c=0.38 id=25% cov=49%
-----------------------------------------------------------------------------------------------------------------------------------------------------VGLAPRD--THPRAVRPGDAIVViggrTGRDGIHGATFSSAELTHTTAEEVGSAVQIGDPITEKkmidvvlqARDRGLYSAITDCGAGGLSSAVGEM--GADCGAEVELARAPL-----KYAGLQPWEIWLSEAQERMVLAVPPQCLERLLALCASED--VEATVIGRYTDTGRLVVR--YNGASVVDL----------
>UniRef50_C2AUB9(37-323:341) Thiamine-phosphate kinase n=1 Tax=Tsukamurella paurometabola DSM 20162 RepID=C2AUB9_TSUPA  E=2e-23 s/c=0.39 id=24% cov=70%
-----------------------------------------------------------------------VGRRAIAQNAADIAAMGAVCTGFTVTLGCPPQTPAALVEAISRGVARGAADAGGA-----VAGGDVVRTEQVLLAVTALGDLQGRAPVLLSGARPGDAVAVCGTLGRSAAGLAALDAGRGVDfPEVVEVYRCPVPPLAAGphAAESGATALTDISD-GLLRDARAMAAASGVRIELDGAALRPDDVLADCAAALGADPdawiRTGGEDHALLATFPAGTVPA------------GWRVIGAVLPAEGaagaVTVDGQTGPER--------------
>UniRef50_B2UP02(452-782:800) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Verrucomicrobiaceae RepID=B2UP02_AKKM8  E=3e-23 s/c=0.34 id=19% cov=89%
-----------------IIREYDHEVQGNTILKPLAGAqadAPQDGSVVDIDGSDKCMAM-ACAILPEWgkTDPYAMGTGTVDECVRQLILVGSNPdkIGLLDNFCMGNPEDPAELGRLvecVKAIAKAADAYNAPFISGKDSFYNYFETEDGPINVpvtflcSGFGVVEnPDHVIGSSLRRSNSLLYLIGHTEDEmGGSVFARTHGVEDGKVPQTDCAANMELYKAyygALTSGLVLSAHDVSEGGLAVTAAEMAFSGKGGVRLDLTKVPTVNGWKSPAV-----PLFSESTGRILVEVDPEFAADFETAMD----GFPCACIGGVTEEKRLT-ATCCGGEKVLD-----------
>UniRef50_C6QR31(10-215:221) AIR synthase related protein domain protein n=1 Tax=Geobacillus sp. Y4.1MC1 RepID=C6QR31_9BACI  E=2e-22 s/c=0.53 id=22% cov=56%
-------------------------------------------------------------------------------------------------------------ETIAQGMAEACRKYGVPMVGGHYLPEETAG-----VATAMVGRATH--LLRCFHGRPGQWLMVAVDLeGRQFKDYLQWDSTsFRTPQDLQSKLAVLPMIAELQLA----TAARDISNAGLIGTLAMLAEASECGARVDLNSIPKPYNVDFSKWI------KMFPGYGFILAVDPEHAGKVQALFQKEQ--ITAQVIGELTEDPNIVL----------------------
>UniRef50_Q1UZ94(5-291:319) Thiamine-phosphate kinase n=3 Tax=Candidatus Pelagibacter RepID=Q1UZ94_PELUB  E=1e-21 s/c=0.37 id=22% cov=50%
----------------ELIKNYFQKlSKKSPSALNLNDDVFFD------KKNKLAVSVDTYTEGNHFIDfkrPDLVIKKIIRSSISDLICKGIKPKYYFISGSGNKKsFSKLNLSKISKSLNQEQNKYKIFLSGGDTVFS-----NKLSFTITSIGFA--DNIIYRNKAKLYDDVYVSGNIGDSYLGLLVLKNKIKLNSRLK-------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q6MIZ0(272-612:1009) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Bdellovibrio bacteriovorus RepID=Q6MIZ0_BDEBA  E=2e-21 s/c=0.31 id=23% cov=64%
---------------------------------------------------------------------------------------GAKPVANTDVFCLstPNLFPASDspqrpellkdpgviFRGVHQGVEEGGNQSGIPTINGAFCFASEFAAKPLIFVGS-VGVMPKtvhGRASESKEIRPGDLIVVAGGrlgkDGVHGATFSSLALHDNVASNVVQigdsiTQKRLLDFTLKARDNGWIQAITDNGAGGVSSSIGEMAQYSG-GARMDLGLHPVKYSGLEY-----WEMLVSESQERMSYAVSPNHLMDFMNLARH--MGVEAFVLGEFTDSGS-------------------------
>UniRef50_C8W0C8(237-563:962) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Clostridia RepID=C8W0C8_DESAS  E=4e-20 s/c=0.31 id=22% cov=49%
------------------------------------------------------------------------------------------------------------------------------------------------------GLLPAERCQKAS-PQAGDVALVlggrTGRDGIHGATFSSAEMTDMTITVNSSAVQIGHAIeekrtsdaILEASQEGLIRAITDCGAGGYGSALGEMGEKIGV--KVFLDRVPL-----KYPGLNPWEIWLSESQERMVLAVAPENMDRVMAICRN--YNVEATAIAEFTGDGRLLV--TYNGENVCDL----------
>UniRef50_Q3AN70(350-601:675) Selenide,water dikinase n=5 Tax=Synechococcus RepID=Q3AN70_SYNSC   E=2e-19 s/c=0.39 id=22% cov=53%
------------------------------------------------------------------------GRLTALHACSDLWACGARVSSAMATITLpmvPANEQQELLVQTLAGIRSVLDEQGAELIGGHTmesrSASPLPASLGVQITLSVNGRSSQS-PWLKSGLQPGDALLISRPLGTGvlfAGAMTGATKATDLDAALKGMAGSQHTLLEQLEPVRGdIHACTDITGFGLLGHLGEMLQNrTGLKILLNGAAIP--------------------------------------------------------------------------------------
>UniRef50_Q2Q0E4(316-608:1008) Phosphoribosylformylglycinamidine synthase II n=1 Tax=uncultured organism HF10_3D09 RepID=Q2Q0E4_9ZZZZ  E=3e-19 s/c=0.34 id=20% cov=22%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DMLLEARDSCLITCTTDNGAGGLSSSIGEMAEYTN-GCEIDLGKVPLKQE-----GLSSWEILVSESQERMTVAVAPKD-----------------------------------------------------
>UniRef50_Q2Q0E4(666-982:1008) Phosphoribosylformylglycinamidine synthase II n=1 Tax=uncultured organism HF10_3D09 RepID=Q2Q0E4_9ZZZZ  E=4e-15 s/c=0.27 id=18% cov=85%
---------------HEVIAQTVVKPFVGVERDGPGDAGLI--APIHGNPQGLVVS---CGIAPRYSD-IDAGAMVAAsidEAVRNAVCVGVDIdkMAGLDNFCWPDPIESEktpdgkfKLAQLVranRELERVCRAYRLPCVSGKDSMKNDYGVwpNKISIPPTMLfslfGNQPDvRKTATSNFKRHGERIYLVGTtyeeLGASEVAFHLRERGDATGiGGQVPRLEDPVRQLEVYRKLsssiqnGLIRTAHDCSEGGLAVALAEMCIGGRCGAIIDID---------GIGSCDVFSRLWSESLGRIIVSVEAEHELAFVEMME----GADIHLIGMVTESPNLIVEDGY------------------
>UniRef50_Q9YFL3(30-301:309) Putative thiamine-monophosphate kinase n=1 Tax=Aeropyrum pernix RepID=Q9YFL3_AERPE  E=6e-16 s/c=0.32 id=21% cov=69%
---------------------------------------------------------------------GDWGWKSVVAAASDVAASGGAPFHVMYSLGLD---SVERAVDVARGVGEAAVWMGATV-----GKSDFNTSKSPWIDVAVLGKAEK--PLGRFGAKPGMTLVQVGASGYGLLSHLTLQGRLsrdDLPGPVVEYTRRPKPPLRIGPELSSCeAAASIDNSDGLGASLHLLGVESGVSVVI--DDILVDRHVEKVLDELGLEkwaVLQSWEDYNIVAVGGDGSIDCILRWCRR--LNIECATVGYTSSDGAGRV----------------------
>UniRef50_A6G366(718-978:1010) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G366_9DELT  E=7e-16 s/c=0.33 id=29% cov=27%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDAGLIRSAHVCARGGLALSLAHMVLASGLGLELELDTDGLSAAAQLFAE----------STGRIVLTCAEAQGEAVEAALGAHGL----QRLGRVVEAPTLRV----------------------
>UniRef50_B1ZQV5(132-415:431) AIR synthase related protein domain protein n=1 Tax=Opitutus terrae PB90-1 RepID=B1ZQV5_OPITP  E=2e-15 s/c=0.30 id=19% cov=65%
---------------------------------------------------------------------------------------GAMPRAVQAHVFVPEALTlpaLARLGDILQGLAEACAYFELGLTG-----VPLTGGAELGLQVAAIGVVAEEKHVTRAVVQEaGENLVLLGEAphelgGSHFVAAVHGLQTGPVPELDLAAEKRLNKTLLALIKGGVLMAVRHVAGGGLLGTAAAMLLAAPRVLGAKLDVTPLGGARADAL-------LFGESQGRVLVAVAASRVGTVLT--EAQIRGVPAVLVGEVTETATLNLKTR-------------------
>UniRef50_Q2W4S4(11-140:268) Thiamine monophosphate kinase n=2 Tax=Magnetospirillum RepID=Q2W4S4_MAGSA  E=3e-15 s/c=0.66 id=29% cov=33%
-----------------LIAELFAPLAAGfpGALGLTDDAAFIAA----EPGFDTVATMDSMVAGVHFLaddPPDLVARKLIRVNLSDLAAKGAEPRLLMLSAAFPRGVTQDWLRTFGAGLAEDVRAFGVHLIGGDT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_UPI0001C369C7(10-183:187) hydrogenase expression/formation protein HypE n=1 Tax=Clostridium hathewayi DSM 13479 RepID=UPI0001C369C7  E=1e-14 s/c=0.48 id=27% cov=31%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGGILSALWNLSGAYMTGIEFSLRQIPVKQETIEVCERYNLNPYRLYSDGCLLFVTDNGGEM----VLSLEREGIHAAVIGRVTEGIGRIIRHG-ESTGYLDRPAED------
>UniRef50_Q8PCQ7(926-1030:1348) Phosphoribosylformylglycinamidine synthase n=11 Tax=Gammaproteobacteria RepID=PUR4_XANCP  E=0.0004 s/c=0.46 id=25% cov=32%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LIRDAREGGLLLAYHDRSDGGAFAALCEMAFASRQGLDITLDAWGDDAFRSLFNEELG-----------AVVQIANEDRAAFADLVERHALTECAQRIARPTGTPRVRV---SGQGRVL------------
>UniRef50_Q21KN9(286-600:1290) Phosphoribosylformylglycinamidine synthase n=13 Tax=Proteobacteria RepID=Q21KN9_SACD2  E=1e-13 s/c=0.25 id=19% cov=32%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAFIHDVGAGGLSNAFPELAKDGGCGAIFDIRKVPNDEP-----GMSPLEIWCNESQERYVMAIPPERLAQFEAICERERC--PYAVVGEAISEQTLQVKDTLLNANPVDLP---------
>UniRef50_A8RQE2(5-196:197) Putative uncharacterized protein n=1 Tax=Clostridium bolteae ATCC BAA-613 RepID=A8RQE2_9CLOT  E=2e-13 s/c=0.41 id=20% cov=54%
------------------------------------------------------------------------------------------------------------------------------------------------------GQGPGGFEKRDGFMRPGQDLVMAGYAGFAGTVKIGAEKRDFLKTRFSSMFLRCLDETEPYsveqwikreqkEEHCSFTVYEYAGEGGVLAALWNLSGIFNAGIDADLRCMPVRQVTVEVCELFELNPYRLYSGNCAVLV--SDRGGQLVRRLREE--GIPAGVIGSVAEGSARQIRHGQVGAGFLERPRPDELTKI-
>UniRef50_Q2SWP3(760-1104:1414) Phosphoribosylformylglycinamidine synthase n=77 Tax=root RepID=Q2SWP3_BURTA  E=2e-06 s/c=0.16 id=28% cov=33%
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AYHDRSDGGLWATVCEMAFAGHAGVSLNVDMLTLDPqhesdygDAKDWAkqtsgrrEDRTIRALFSEELG-AVVQVRAADRDAVLGALREQGLSACSHVIGAVNETD--VIEVYRDAKKIYEAPRVEL-----
>UniRef50_Q6AQE0(729-944:1267) Probable phosphoribosylformylglycinamidine synthase n=1 Tax=Desulfotalea psychrophila RepID=Q6AQE0_DESPS  E=4e-06 s/c=0.25 id=22% cov=31%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQEMIDAGLISAGHDRSDGGLVTTMLEMAFAGNCGLKIELS-----------GDVSAHDYLFNEELG-MMIECVPGAEAEVEEILVAA--GITPVALGFTTADKNISI--SYNGEQVLNR----------
>UniRef50_D1PUA6(317-566:1278) Phosphoribosylformylglycinamidine synthase n=6 Tax=Prevotella RepID=D1PUA6_9BACT  E=3e-07 s/c=0.23 id=16% cov=48%
--------------------------------------------------------------------------------------------------------------------------------------------DKVIMLASGVGYGKKRDCLKKEPRKGNKVVVVGGDnyrIGLGGGSVSSVDtgrysNGIELNAVQRanpEMQKRAYNLIRALVEEESnpVVSVHDHGSAGHLNCLSELVEECG--GEIDMTQLPIGDKTLSAKEIIANE-----SQERMGLLIDEKHLDHVQKIAERERA--PMYVVGETTGD---------------------------
>UniRef50_D1IDG9(431-724:942) Whole genome shotgun sequence of line PN40024, scaffold_19.assembly12x (Fragment) n=3 Tax=Vitis vinifera RepID=D1IDG9_VITVI  E=6e-07 s/c=0.20 id=30% cov=29%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQELLADGSISAGHDISDGGLIVCVLEMAFAGNCGIALDLTSHGNSLFETLFAEELG-----------LVLEVSRTNLDMIMGKL--HGVGVSAEIIGQVTATPMIELK---------------------
>UniRef50_Q3KSV4(741-981:1318) Major tegument protein n=6 Tax=Lymphocryptovirus RepID=MTP_EBVG   E=0.0002 s/c=0.21 id=29% cov=21%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HDISDGGLVTCLVEMALAGqrGVTITMPVASDYLP-------EMFAEHP-------GLVFEVEERSVGEVLQTLRS--MNMYPAVLGRV------------------------------
>UniRef50_Q016J3(624-757:1078) Putative formylglycineamide ribotide am (ISS) (Fragment) n=2 Tax=cellular organisms RepID=Q016J3_OSTTA  E=0.0002 s/c=0.37 id=24% cov=28%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WSATQKLVDERKISAGHDVSDGGFITAVLEMAFPSttaGVEVTLPGDDAMS----ACFAEELAI-----------VLEVAPENEAAVMSAY--ASVGVTARAIGKVTNDGKCTV----------------------
>UniRef50_C1F4L5(37-374:374) Hydrogenase expression/formation protein HypE n=5 Tax=Bacteria RepID=C1F4L5_ACIC5  E=2e-83 s/c=0.92 id=47% cov=98%
--NIVMGHGSGGKLSAELIDKIFVQRFRNPILDRMDDQAVLE-----IGGMRLAFTTDSFVVTPLFFPGGDIGHLAVNGTVNDLAMCGARPLYLSAAFILEEGLPTQDLARVVESMRDAANAANIQLVTGDTKVVNRGKGDKVFITTTGIGIVDRPTEMSADRAQPGDKVILSGFIGDHGITILSQREHLEFESDLKSDCAPLHSLVEAMLNEAeangnikGIRCMRDPTRGGVATVLNEIARKSHVGMRLHESSIPVRESVRGACEVLGLDPLYVANEGKLLAVVAPQIADQLIVRMRKHPLGTESQIIGEITGQPRdmVLMKTSIGGTRVVDVLFGEQMPRIC
>UniRef50_A8A9S1(2-337:337) Hydrogenase expression/formation protein HypE n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8A9S1_IGNH4  E=5e-70 s/c=0.79 id=37% cov=99%
---VTLAVGGGGRETEEFIKNFILPLFKIRSLGsVGLDDLEDGAAVPIGDNKYLVVSVDSYTVSPPFFPGGDIGKLAATGSLNDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMSEVTNSLNVALLGGDTKVMPKGSVDKIVISTVGIGIAEGP-LLTLDRGEPGDKVLVTGPVGDHGATILALQFGLQVKT-LKSDVRPVWPAVKALREALGedLKAAKDPTRGGLAMALNELAERSKTTVYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKAGF-EEAAIIGELRKGKPGYVisRTPVGGLRLLEKPSGELVPRIC
>UniRef50_A6C222(25-358:358) Hydrogenase expression/formation protein HypE n=1 Tax=Planctomyces maris DSM 8797 RepID=A6C222_9PLAN  E=2e-67 s/c=0.77 id=47% cov=99%
-DCVTLAHGEGGRLSRKLIQERIASVLKNEFLETSDDAARL-----PRVDGPLAFTTDSFVVSPLFFPGGDIGSLAIYGTVNDLAVSGAHPLWLTLSLILEEGFPLMLLDRVLQSLAEAASSTAVKIVAGDTKVVPRGAVDGLFINTAGVGKLTEPVPPGPAFLREGDELVVSGPIGQHGIAVLAAREQLQLDPLPHSDCGSLLTAVEQLREALGdrICCLRDATRGGVAAVLQEWAGSSGLTLSIDERCVPVTPGVKGMSELLGLDPLHIANEGTMLIAVRQGAGQEAVSVLQSLSKTADARLIGSVKGRGvaAVTVKRTLGLEQPLHDPLGSPLPRIC
>UniRef50_A3DKG6(7-346:346) Hydrogenase expression/formation protein HypE n=1 Tax=Staphylothermus marinus F1 RepID=A3DKG6_STAMF  E=5e-61 s/c=0.70 id=32% cov=98%
---ITTVHGSGGFETLEIIEKLIVHRVPenlRKVLDGVGLDVLDDGSSMRIGNTHIVISTDNFTVKPLFFPGGDIGHLAVSGVLNDLVMMGARPIAFMDGIIVEEGFPRDDLDRILESMIKLLKENNVALIGGDFKVMPKKSLDGLIISGTGIGLAEKPII---DKIKPGDKIIVTGPIAEHGATILAAQLGmLEQAQGLRSDTRPLVKTVLPILEKYRdhIHAARDPTRGGLSIVLNEWVRGTKYTIVINRSTIPIRDEVRQFLDALGIDPLGVAGEGLAILSVDNEVADEIVEELHRRGEPY-ATIIGEVIvpEEEylagRVIAITEVGGKVVVQ-PNALNLPRIC
>UniRef50_B0VPT8(5-289:305) Thiamin-monophosphate kinase n=18 Tax=Moraxellaceae RepID=B0VPT8_ACIBS  E=2e-52 s/c=0.73 id=22% cov=66%
----------------SIIDQYFNRQsHPDVALGIGDDSALI----TPPPNQQLVICADTLVAGRHFpleTLSHAIGWKSVAVNLSDIAAMGAKPHSILLAISLPQ-VDHEWLEGFSQGIYDCCNQFGVALIGGDTTQGPH-----LTITVTAMGWIETGKAVLRSGAKVGDYVCVSGQIGDAAYGL------QHLGHSLQQRLDYPTPRCKLGEELKGLASSMIDVSDGLAQDLGHILKASKVGARLILEKLPVDP-----------------------------------------------------------------------------------
>UniRef50_A1S0T2(7-331:335) AIR synthase related protein domain protein n=2 Tax=Archaea RepID=A1S0T2_THEPD  E=1e-50 s/c=0.62 id=27% cov=94%
-----------GKLTYGELEELLSRLRRQDASVLLGPAIGEDAALIDLGDKVLVVHADPITGAV-----SNIGWLSVHVSANDVATRGVQPRWLVTVVLLPEGAGQDVLWDIAGQLRKAADEIGATIVGGHTEFTPG--LDRPILVTTAMGVGGKGEVLATSRARPGDALILTKGAGIEGTAILATELYDELSRKVDREVLeraksfiyevSVVKDALTAVRAGGVHAMHDPTEGGVLGGLQEMAIAANAGLVVEEEKIPVREETKAVCRALGVDPLRLISSGSLLIAVEGSRARDVVDALSRE--GIPAAVIGRLTEGSERILVKRGGEIVDLNEPVVDELWRI-
>UniRef50_A8PLC8(7-311:323) Thiamine-monophosphate kinase n=2 Tax=Gammaproteobacteria RepID=A8PLC8_9COXI  E=1e-50 s/c=0.66 id=21% cov=87%
----------------ELIQRFFnqpMKCRNDVTLGIGDDGAVLN----VPFNQQLVVSTDTFVAGRHFPEetlPEDIGYKALAVNLSDLAAMAAEPAWILLALTLP-HVDETWLKKFNQGFFSLIQQFQLQLVGGDLTRGP------LSITVHALGFVPQGKALRRLGAHIGDKIYVTGTLGDAGLALALMNtpsccgLTQSQIFSVKQRLHRPHPRVEVGIALRDIASCAIDISDGLMADLHHLLSANQVGAIVQLEKLPLSDSLRGLSpEKAWSLALSSGDDYELCFTVPESKERDLQQQL--ATINTPYQCIGHIKADSGLILLDKKGA----------------
>UniRef50_A8MLK1(4-326:330) AIR synthase related protein domain protein n=3 Tax=Clostridiaceae RepID=A8MLK1_ALKOO  E=6e-50 s/c=0.62 id=22% cov=93%
-----------GKVPTEVLKEVIFSNLKNRRPEVLvRPNIGEDCAVVDFGDYVCVMSTD-----PITGAAKDIGSLAVHISCNDIASSGVEPLGIMLTIMAPPHTTKEDLSLVMSEANKAAASVNVEIIGGHTEITD--AVNRMIISATAIGRQLKEKLVLSEGAKIDDAVFMTKYTGLEGTAIIARDLEEKLkekisDATIQTAQEFLKDIsvVKEGITAGevGVHSMHDVTEGGIFGALWELGEASGIGIEIYEDQIPMRPETLEICHYLSIDPMRLISSGVMVMTIAQDKKEALMEAFKRENLIL--TEIGRMVEKDRIIISAAKG-IRALDPPDVDEL----
>UniRef50_Q5FNA0(18-316:325) Thiamin-monophosphate kinase n=1 Tax=Gluconobacter oxydans RepID=Q5FNA0_GLUOX  E=9e-50 s/c=0.67 id=22% cov=85%
------------------IARHFRPLAGAESLDLRDDCALMRC----PEGEEFAISTDTMVENVHFLpddPPETLGRKLLRCNLSDLAAMGARPHAYTLNVTVTRGgrHDENWFAAFSRGLAEDQQRYGVHLIGGDTTSISG----PLVLSATVFGLLRHNTALRRSTARPGDEIWVTGTIGDAALGLLVLQGSLQDPSGFLAERYHL-PRPRTGLHLHGIVSAAMDISDGLIQDCGHIAEESGVQLVVDAEAVPVSSAAASLGHEWLMRRLCGGDDYELLLTCAPERSAALQAACQAAE--VPVHRIGTVRTGSGVRL----------------------
>UniRef50_Q6AKX6(10-315:328) Related to thiamine-monophosphate kinase (ThiL) n=1 Tax=Desulfotalea psychrophila RepID=Q6AKX6_DESPS  E=9e-49 s/c=0.64 id=21% cov=86%
------------------IQQHLTAYNEKVICGIGDDCAVFSG----DNGRPWLITTDTLVEGHHFDlswhPAYELGCKAMAVNISDIAAMGGLPVHATISLTFTKDTEEAWLDEFIRGLAYMHHRYNINLIGGDTV-----AGERLSITVTLLGQAHKE-PVYRHGAMPGDIIYVGGPLGSAAAGLFLFQNHRDEIETLKdeyasllRHHLAPMPQVELGRALADsdyIGAMQDISD-GLATDLAHIAKKSAVQAVVFEDKIPVLPEFTRLCKRYQLTatelALGGGDDYLLLFTVRAGREKEVERLARSVQAM--AYPIGLITEGSGVMLKGPTG-----------------
>UniRef50_A0L3Z7(14-326:338) Thiamine-monophosphate kinase n=1 Tax=Magnetococcus sp. MC-1 RepID=A0L3Z7_MAGSM  E=2e-48 s/c=0.62 id=24% cov=86%
------------------IQHIFAPiqskQGEGVQLGIGDDAACL----VVPRTQDLLATTDTMVEGIHFssdADPYLLGQKALAVNLSDIAAMGGLPRWYLLSMAVPNRTSQSWLEEFARGVKAASEMFHVALVGGDTVRSNA----KIVITVQMLGLIGQHRAVARSGAQVGDRLYLSGTLGDSAFGLAHLLGKLpamlaDDVSYLSRRHHLPEPRIQLGMALqdAALAHACIDVSDGLLADLQHICEASQVSAVVDVEKLPFSESAQRVIAQYGRSalelALTGGEDYELLFAISPGAADQVEKIV--HQVGVSLVEIGEVVgvgERPGVVVR---------------------
>UniRef50_A8ZNV6(9-333:339) Hydrogenase expression/formation protein HypE n=2 Tax=Bacteria RepID=A8ZNV6_ACAM1  E=3e-48 s/c=0.60 id=22% cov=92%
-----------GKLPSHLLAHLLSQTPIHDPQVLLGPGIGHDCAVVDGGAKLWVIKSD-----PITFVTDDIGWYVVQINANDIATTGATPRWLMATILLPEQRTTATLaERIHQQIYTACQEINVSLIGGHTEI--TYGIDRPIVVGTLIGEVARDSLITPRGAKPGDRILLTKSVPIEATAILAREYSEQISQALTSDELTqargylYKPGISVLRDaqlanqAGQVSAMHDPTEGGLLAALWELAQASNCQLVIDLEKVPISDLSAHICRVFKIDPLAAIASGALLLTAPQRDAPSICRTL--NTSGIPCCEIGDVQSGNAtVWSRTALEKER-LPCPSRD------
>UniRef50_Q9V1N8(10-302:310) Probable thiamine-monophosphate kinase n=3 Tax=Pyrococcus RepID=THIL_PYRAB  E=4e-48 s/c=0.66 id=21% cov=82%
------------------IISLFMKHFERHSLG-------DDAGFIKLNNSWLLVTSDMLVwktDVPDFMTPEDAGRKVVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDT-----NEADDIIIDGGSLGI--GKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEEKARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEIVSDPVKVALASGEEFELLFTIPREKVEEL---------DIDFKIIGRVEGGNGVYIK---------------------
>UniRef50_A4YFC4(3-323:332) AIR synthase related protein domain protein n=3 Tax=Sulfolobaceae RepID=A4YFC4_METS5  E=5e-47 s/c=0.59 id=21% cov=93%
-----------GKIDRKVFDEVIYPHLGKRLDEVIVpPLTGVDTGAIDLGDRVLVVKTDPVFIVPQF-GMKKASWFAVHILASDVMTSGIPPRYALLDLNLPPSMTDEEFREMWVGIHEALLEIGVMVVGGHTGRYEG--VNYPMVGGfTMIGIGEKEKLGHPSKVKPGDYVIVTKGPAIEATGLLTNLYPEFFRERMRSDLFkealdMYWKMScwkdGLIASQVGIHMMHDATEGGLWNALVEISEVTGKRINLVGERLFINPAVREVTRIVGIDPFSSISEGTMVIVTDKEKVKE--ELLRN---GIEAEIVGRVESGEGVYVDG-----KRIEKPSEDPFWR--
>UniRef50_D1R9A7(11-329:333) Putative uncharacterized protein n=1 Tax=Parachlamydia acanthamoebae str. Hall's coccus RepID=D1R9A7_9CHLA  E=4e-45 s/c=0.58 id=22% cov=75%
----------------------------------------------------------------------DLGYKTIAVNVSDVAAMGGTPKFAFLTLALPSTVHCEWTRLVLQGIKEACEKWHIQLLGGDTV----GSRRDIFINLTLIGSAPQKHIRYRNQAQLGDRICVSGNLGNSGGGLQALKEKIQTTPEvkiLLEAHFRPTPHIqqgRWLASQPGVHAMMDVSD-GLDFDLKRLIKSSHKGAHVDISKIPLSEELLKMAQTKGWNPlqlaLTGGEDYCLLITIDQKKQGVIQDFFKK--FGAPLYEIGQITDQVNELTYYDHGEKKEIDFP---------
>UniRef50_Q2RKM3(1-331:528) AIR synthase related protein-like n=1 Tax=Moorella thermoacetica ATCC 39073 RepID=Q2RKM3_MOOTA  E=1e-44 s/c=0.55 id=26% cov=85%
------------------VDDAFFRQAILPHTGAGDPEVvvgprmGVDAAVLKIGEEYLAVAEDPIFPGP-TTSPDDFGWITVHIGASDVAVMGIKPRFMTYSLLLPPGTPEDYIAGLVRSISTYARELGITIVGGHTGFYGAVTIPTIG-GITVWG--RGREVVTPAGARVGDAVIITKGAAIEAAALVACELGEKLLAAGISPdlVARAKKRLREMsvvaeagiaVEVGGVHAMHDATEGGLARGLWEVAEASGVGLRIERARVPVPADIRAVCDYIGLNPYEVISEGTLVLTCAPEKADAMLAAFK--EAGIEAAVIGRVV-----------------------------
>UniRef50_Q5WJP9(6-321:330) Thiamine-monophosphate kinase n=3 Tax=Bacillus RepID=Q5WJP9_BACSK   E=6e-44 s/c=0.57 id=19% cov=74%
-----------------------------------------------------------------------IGRKALAINVSDLAAMGAVPQFYLVSIAIPPNWSAEELTSLYEGMRAVGDRYGMDLIGGDTVSI----KDSLVLSVTAIGRVKKGCALFRNQAQPGDVVFVTGPVGGSAAGLELLDQRGRFGAfteqerRYVHMHQEPVPQVEmgKMLAEQPYRVALNDISDGLASESMEIAEASGVQLVLDQQKVlELSPQMDSVLPEKRVKWsLNGGEDFQLVGTMTDSAFSSCCEA--AQQQGRHLYKIGFVRAGEPAVLLASETGEQALQM----------
>UniRef50_B0R9W2(8-314:340) Hydrogenase expression/formation protein n=3 Tax=Halobacteriaceae RepID=B0R9W2_HALS3  E=1e-43 s/c=0.58 id=29% cov=88%
------------------IDAEFFAQHLSPNLGADDDAVtvgpqyGVDFGVLSIGGQRLVVSADPVSVNP-GVGIERAGRLALHSVLSDVAVSGVPPSFLSITLVLPASARDDTIAALWDAMATECERLGVSVVTGHTARQD--VSFPWIGGATAMGVGDPAEIVRPDGATAGDTVLMTHSPGAEVAGLFAALFGDHLdvaDDTVERADARLEDTTvvgdACAAASAPVTAMHDATECGIQGALVELATAAGVSISVSSDAVPVPEDVSAVCADLGLDPWQVSSRGTLLVTVPEAHADTAMAALDAR--NTPVAAIGTVSEGSGVTVDGT-------------------
>UniRef50_Q2S9S1(5-311:325) Thiamine-monophosphate kinase n=1 Tax=Hahella chejuensis KCTC 2396 RepID=Q2S9S1_HAHCH  E=1e-43 s/c=0.58 id=25% cov=69%
----------------ELISRYFHAPFANfPNVGRLiETGIGDDCAVLTPLSGRLVISTDTCVSGAHFpvdTSAEMVAARSLGSSVSDLAAMGAEPVGFTLALTLPT-INEAWLQAFGSQLYESALAWRIPLIGGDTTKGP------LAVTVTVLGRV-QDQCLYRHGAAPGEDVWVSGSLGDAAAALSLLGRPDAsltpIERWLYQRYASPQPRLRLGSMLRGIATAAIDISDGLIADLAHICSASNCGALIEEGAIPLSPA----------------------------------------------------------------------------------
>UniRef50_Q0BTF2(20-325:331) Thiamine-monophosphate kinase n=2 Tax=Acetobacteraceae RepID=Q0BTF2_GRABC  E=2e-43 s/c=0.58 id=22% cov=87%
-----------------MIARYLAPLAAAGGLNLTDDAALLQ----PPPGLSLVLAADAMVEGVHYLPGTDphlLARKLLRVNLSDLAAMGAAPLHYLMTLALPRGTDPApWFTAFTAGLAEDQGIFGITLLGGDTTSI----KGPACLSLTVIGTVEPGKAVRRQGACPDDEIWVTGTIGDGALGLLALTEGLADPDDFLAGRYHLPSPRLGLIDQSLVQAAADISD-GLLQDLGHLCTASGLDALVEADTVPLSDAARRHMPEYLPLCLSGGDDYELVMAVSPSCTVPLRQ--RADSLGIPVQRIGRFHARsgqkPGVHVLASDGS----------------
>UniRef50_D1AS58(40-334:349) Thiamin-monophosphate kinase n=5 Tax=Anaplasma RepID=D1AS58_ANACI   E=2e-43 s/c=0.60 id=19% cov=85%
------------------IEKYIRPLMRSGFSTENDDA-----GKISSPNGSFIVTQDILVEGTHFLRhsnPTLLAKKALRVNLSDLAAMGAQPYGYMLGMSLPQGVTEEWWEQFSNGLREDNKNYNVNLIGGDTTSNNTGT---ITISITAMG-VPGMQSMTRSQAKVGDFLYVSGNIGDATLGLMAYQDLIGGEYfALKRRYDLPEPRITLGSKICGIASACIDISDGLVQDIGHICRLSNVGASIHLNQIPMSDaaqDVLRRNPELIERICSGGDDYELAFTSAESNHTKIMHI--AADLGVKVTTIGVIVRQPGVEV----------------------
>UniRef50_A1K2S2(25-327:336) Thiamine-phosphate kinase n=9 Tax=cellular organisms RepID=A1K2S2_AZOSB  E=3e-43 s/c=0.59 id=22% cov=88%
-----------------LIQRHFSRPCGHTALAGGDDAALL----HPRPGMELAVSADMLVAGTHFFPdadPHDLGWKTLAVNVSDLAAMGADPRWALLS-LALPAADDAWIAAFADGFYACAERFGVDLAGGDTTRGP------LTLSVTILGEVPRGQALTRAGANAGDDIWVSGQPGLAALGLEMLRGTFAPTADGERCLAalhRPQPRVALGQALRGLASAALDISDGLLGDLGHILVQSRCGATLHEDALPLAALYATGASpaLARRCLLAGGDDYELLFCAPPAARAAITAL--GPALALPLTRIGTLSDAPGtVALRSADGTLTAL------------
>UniRef50_D1J9H7(13-327:335) Thiamine-monophosphate kinase n=1 Tax=uncultured archaeon RepID=D1J9H7_9ARCH  E=5e-43 s/c=0.56 id=20% cov=87%
---------------ERIVEKFRVDREMVTVGAGDDDCAVIDIEKVRNRFKHLVITTDTLQESTHFphgISAFQMGWSIVAVNLSDVAAMGAYPFAFTIAMGIPAQTETSFLDELVAGIEKCAASYNTSVVGGDITMS-----KELILTGTCFGFA--DRPVRRAGAKEGDLICVTGSLGNAALALKLMRGELKVPGdvgvEVKKALSQPVPRINEGitIANSGVATSMIDISDGLALSLAEIAKRSSVGVELYEDKVPvlsdeIRSDLRLSTREQRELAYYFGGDYELLFTIDAGALenEQVMSELIKE---VKMSVIGKIVPqNEGIYFKN--------------------
>UniRef50_D0MD26(16-338:358) Thiamine-monophosphate kinase n=1 Tax=Rhodothermus marinus DSM 4252 RepID=D0MD26_RHOM4  E=8e-43 s/c=0.55 id=24% cov=88%
-----------------LIDRLqtIVADLSDPDLimGIGDDAAVYR---LPDEETVHVITTDALLEGVHFDrlmtPMEHLGYKAIAVNVSDVVAMNAEPRYATIAVGIPAKISVEMMEAFYRGVRRACEKYGLVLVGGDTT-----AAHTLCISVTVVGEARMEDVIFRRGARPGDLLCVSGDLGAAYAGLkilleqrrALKEKGADYQPDLEPYRYVIQRqllpearldVIRDWRDRGVRPRALIDVSDGLASEVHHLCRHSNCGAIVYASAIPVALETREVADHFAEDvdtyALFGGEDYELLFALPPEQLELL--------DPTSFNVIGEFLpADQGVQVQTPEGAIIPLEP----------
>UniRef50_Q8TY09(405-717:724) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Euryarchaeota RepID=PURL_METKA  E=7e-26 s/c=0.38 id=22% cov=81%
--------------------------------KPGHDAAVMWLQHEGLEDVALALTTDSNPRHVLIDPKTGT-EGCVAEALRNLATVGAEPLCLVDCLNFGSPENPRVyyqLRRSIEGLGKAAREFEVPVVGGNVSLYNEHEVDGPVNPTPVIGAVGVIRGLDyledfPREPEEGEAVIVLGETREELGGSLYLIEYHGIKGGKVPRVRYreeraLHDLLRRIARKNMVSSVTDVSTGGLLAAVAELLGPVGASLSLSEVPNSVSRWDFL---------LLSESHGRAIVTT--DRPDDVLGA--AEEAGVPAQVVGEVTGDG--VLRISVG-----------------
>UniRef50_C8S8T5(19-294:301) Thiamine-monophosphate kinase n=1 Tax=Ferroglobus placidus DSM 10642 RepID=C8S8T5_FERPL  E=2e-42 s/c=0.63 id=21% cov=68%
-----------------------------------------------------------------------IGWKAVTASVSDLAAMGAKPIYFSYSLGLSRE-EISFVEDLMKGIREALDFYGMKFLSGDT-----NESTELVLDSVAVGIAR--NLLLRSNAKVGDAVCVTGDLGRAYCSLLYlLEKVEEIEEKILEKFLKPVARVDEGLKLANIANSAIDVSDGLSKELNLLANSSGVMIKVFEDRIPIREEVLEFCTSNNLNPievaLNSGEEYELLFTVSKDKLEDL---------DFEFSIIGEVSKGEGVFLVGK-------------------
>UniRef50_C0GR51(10-311:315) Thiamine-monophosphate kinase n=1 Tax=Desulfonatronospira thiodismutans ASO3-1 RepID=C0GR51_9DELT  E=3e-41 s/c=0.57 id=27% cov=83%
----------------EIVNSLFPREHPHMVVGRGDDCAVLKCPA------SLCMSSDLFLEDVHFrtryFTPEDIGHKALAVNLSDLAAGGARPLGFNLNLIWPVYLDEEFCRSMLSSMAELGAKFKLALTGGDLSF-----GKSLGLAVCIWGKSPARQML-RGKAEPGDVLFVVGKAGLAACGLSLLEEndpGLDRYPECVAQHLRPRPLVREGQVLAGieeVKGLMDVSD-GLARDLPRFCRR-GTGVEICSD-FRVHPEVAFFCRDRGLDPlataLKGGEDYALLGACTRKGWDTVKKKI------LDCRRLGTVTDKPGIFLQ---------------------
>UniRef50_D1PUY6(11-355:370) Thiamine monophosphate kinase n=6 Tax=Prevotella RepID=D1PUY6_9BACT   E=2e-40 s/c=0.49 id=18% cov=54%
--------------------------------------------------------------------------------ISDIFAMNGTPRQMTVSMAIGKRFKVEDIEAFYKGLRSACDKWSIDIVGGDTT----SSYTGLAISITCIGEARKEDIVYRNGAKETDLVCVTGDLGAAYMGLQLLEREKEVyyqqiddinrkikeaqkagneeavkhfqeqgshianfqpdfagKEYLLERQLKPEARgdmIQLLREHNIRPTAMMDISDGLSSELLHICKRSNCGCRIYEKNIPIDYQTAIMAEELNIN-----------------------------------------------------------------------
>UniRef50_B1L7H6(5-311:320) Thiamine-monophosphate kinase n=1 Tax=Candidatus Korarchaeum cryptofilum OPF8 RepID=B1L7H6_KORCO  E=3e-40 s/c=0.55 id=22% cov=89%
---------------RELIDEIIGLVSEDPygLLRLGRD----DASARRLNEGIYVFKMDMVSSSTDLLPGMslrQLAKKCVVANFSDVASKGARPLLFMCSLGLPRGMRDEEFVSIFEGFEEAMRKYGTYLVGGDL-----GESEELIISGFAFGRVE-GRLVGRGGSRPGDIVMTTGSFGLTWLGFKHLLEGLELPEGLRRRalksVYEPEARVEEGIIISNYATSTVDSSDGLYWSLKELSRASGNGFLIEE--LPLDEEVGLFLGGDSISaAFHGGEEYEIVFTLREEDVAKVRDEL--TVLGVEPIKIGRVVEGGGIRLRA---GNELIEVPEG-------
>UniRef50_A9A265(16-334:340) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Thaumarchaeota RepID=A9A265_NITMS  E=2e-39 s/c=0.52 id=17% cov=88%
------------KQSQMAIGKLISSTHKLQKKAKIAHGFGHYAGIVEIPGGKLLAThTDGVGTKVVIAnmmkKYNTIGIDCVAMNVNDIICIGATPISFVDYIAANKN-DVPIFKKIVEGLVKGAKKSAMPIVGGETAIMPdviEGKGFAFDLAGMVVGLVEKKQMVLGNKIRAGDVIIGANSTGIHSNGYSLARKALLkkysvkdkvkgvgtIGDALLKPTEIYTKPVLEMVEKCKINGLAHITGGSFTKLLR--LKKIGYEID-SLPKIPPIMGLIAEQGVKSEEMYKTFNMGvGFCVVAPKDQATKIKSIFKKYK--ISSQEIGQIVSKKGVFV----------------------
>UniRef50_A8I0K0(37-352:358) Thiamine-monophosphate kinase n=28 Tax=Alphaproteobacteria RepID=A8I0K0_AZOC5  E=3e-39 s/c=0.52 id=23% cov=90%
----------------DIIARYFRPIATHAEARGLFDDA---ALLTPPPGCDLVLTKDALVAGVHFFaddPPASIARKALRVNLSDLAAKGARPLGALLAIALPRPMDPEWLGAFAEALGADAERFGCPILGGDTVSTPG----PVTLSITAFGAVPTGGFVPRTGAAPGHALLVSGTIGDAALGLQLRLAPDrpgfealsaEQKAFLADRFLHPQPRLPLAEALRDHAAAAMDVSDGLVGDFAKMMSASGCGGLVRAAQVPLSDaaaAAIAAEPALLADVLGGGDDYEIATAVPHDAVPVFRAAAQAAGIAV--TVIGETYKGDGLDLVGLDGQPLYLDR----------
>UniRef50_C6CVI9(23-321:349) Thiamine-monophosphate kinase n=1 Tax=Paenibacillus sp. JDR-2 RepID=C6CVI9_PAESJ  E=1e-38 s/c=0.54 id=22% cov=57%
----------------------------------------------------------------------DIGYKALASNVSDIAAMGGVPLQALVSVSVPKQLGPEPMHRLYDGLYACAEQYGVAVIGGDTTSSPQHLVVAVTVTG----AVEAGKALRRSGAKPGDAVVLTGPVGKSAAGlhFLLAQRERGADalageraaAQLVQAHRRPSPSVRAgrlLLARGTCHSLNDVSD-GLASEAWEIAEASGLVVSLFEKHLPRSGSMAAYAGVAGIDP----------------------------------------------------------------------
>UniRef50_C6LD50(4-358:362) Hydrogenase maturation factor n=1 Tax=Bryantella formatexigens DSM 14469 RepID=C6LD50_9FIRM  E=3e-38 s/c=0.45 id=22% cov=75%
-------------------------------------------------------------------------RFAIEHAVNNLACAGSEPEAVLLTVLLPENTEEAFLKEVMREAEAVCKELGIQIAGGHTEVNPAVML--PLLTVTALGAAPSgattskaiapratpsgeaasgaatsgvhgagamDSYLRAAGAQPGMDVLIAGTVAREGTALLAWAHEEELKKRFPADFVEQAEsfgssisilQAARVAMQCGAAALHDASQGGIFGALWELCEGAGCGLTADLRKIPIRQETIEICEYFGYNPYCLLSGGALLVVAPDGRRVE----MELARHGITAAVIGKLTDSNDRILLNG-EERRFLDRPAQD------
>UniRef50_B1Z181(16-351:354) Selenide, water dikinase n=141 Tax=Bacteria RepID=SELD_BURA4   E=3e-38 s/c=0.48 id=24% cov=75%
--------------------------------------------------QAIVATTDFFM--PIVDDPFDFGRIAATNALSDVYAMGGKPILALALVGMPiNVLPHETIAAILRGGESVCAEAGIPVAGGHSI-----DSVEPIYGLAAIGVVHPSRVKRNAAARAGDVLVLGKPLGVGVLSAALKKNQLDAAgyAQMVATTTKLNRPGAELAALPGVHALTDVTGFGLLGHTLELARGANLTARVHYASLPWLAGVEAFvadgvftgasgrnwaaygtdvrladglppvAQALLTDPQTS---GGLLVACAPEAVDDVLACFRADGFDR-AAVIGEMVDGPSRV-----------------------
>UniRef50_B2RLG7(16-340:348) Selenide, water dikinase n=4 Tax=Bacteria RepID=SELD_PORG3   E=8e-38 s/c=0.49 id=23% cov=79%
------------------------------------DVSTHDDAGVyrLNDDTALIVTTDFFP--PVCSDPYTFGRIAAANALSDVYAMGGRPLLVLNLTMFPsEGIPVEVLADILRGGQQTIDESGAFTMGGHTIDDPI-----PKYGLAVTGIVHPEHLVTNAGVRAGQCLVLTKPLGI-GVAMAAHRLGLigsEVYEAAIGQMCLLNRAGAELMQKYGIRGATDITGFGLLGHAKELAEASDVCLHIDSRSVPVLPECLSLLRDGCIpgatfrnlrfvgDMLRadcpteykmlladAQTSGGLLMAVDADRAEDLVADLHRTGLHPFAAIIGYATD----------------------------
>UniRef50_D1U5K6(9-312:317) Thiamine-monophosphate kinase n=1 Tax=Desulfovibrio aespoeensis Aspo-2 RepID=D1U5K6_9DELT  E=1e-37 s/c=0.52 id=22% cov=84%
----------------DLIGAHFPTGHEFLRLGRGDDCAVL------AGGSDICVSSDLFLEDVHFrrgyFTAEDIGYKALAVNISDIAAMGARPFAFTMDLMIPPDLDEDFWNGFFKGMSALARHNDLALAGGDLSRADRL---GVSISIFGVG-GSKGRFLTRGNCAPGDILFTVGDLGLARAGLmtleaLGEKGREAFPTAVLAHLRPkPKVLIGTLLNAAGIKGLMDVSD-GLARDLPRFLGP-KVGADLTIPTNVLNGNVIAFALATGADPvelaMLGGEDYALLGVMDEETREKAASV-------PGFTELGRVTDTPGILVNGK-------------------
>UniRef50_B4CVD4(35-346:350) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Chthoniobacter flavus Ellin428 RepID=B4CVD4_9BACT  E=1e-37 s/c=0.51 id=20% cov=68%
----------------------------------------------------------------------------VNHCVNDIAVVGARPLFFLDYIGA-ERLDPPVFQQLIKGFAKACKEAGCALIGGETAQMPGmYQQGEYDLAGTIVGVVDRKLALDGSRTKVGDVIIGLASNGLHTNGYSLARKvlfekmglhvdsmlpgvAKTLGDELLRVHKNYQPLLAKL-PQGMIKGLAHITGGGLIDNLPRVLPKT-TDAVIDTKTWKVPAIFEHIREGGSIDrteMYQVFNMGiGMTVVVSAADREKALKLTKG-------KVIGRIEKGSGVV-----------------------
>UniRef50_Q1JXC5(13-324:326) Selenide, water dikinase n=1 Tax=Desulfuromonas acetoxidans DSM 684 RepID=Q1JXC5_DESAC  E=3e-37 s/c=0.51 id=23% cov=70%
-----------------------------------------------------------------------FGAIAAANALSDVFAMGGQPITAMNMVGFPNCLPVDVLTEILKGGTAKVHEAGATMVGGHSVEDE-----EPKYGLAVTGTVHPDNLITSQGCKPGDILVLTKPLGTGLLTTALKAEviNEAQITEALQGMARLNRYASEAMRQVGISACTDVTGFGLLGHALEMAEASGIRLLISGSSLPEYPLARDMAEtglvpegsfrnnrhymprvtgaehqaqadiDLLCDPQTS---GGLLMAVHPERLDALCQALKHA--GDHAFVIGEVADGPAGTME---------------------
>UniRef50_A5ULE1(44-317:334) Phosphoribosylformylglycinamidine synthase-related protein (Selenophosphate synthetase) n=7 Tax=Euryarchaeota RepID=A5ULE1_METS3  E=7e-37 s/c=0.57 id=19% cov=67%
--------------------------------------------------------------------------------VNDIAAMGGKPLAMVNIMSVKHD---EIYENLLAGIKDGCLKFGVPMVGGHL--HPDGEVD--SLGVAIVGIAKKDKLITSFGAEVGDKIIVAIDLdgKPHEMFELNWDTTYDKDKQLVQDQIT---AVQYLAERDYIKSGKDISNPGILGTLEMLLETSDKGAIVNLEDIPKNE------NISWENWLKSYPGSGFIFTANEENCEFIKKYLK--DYSIEANVVGEVTGECSLYLVNGDGEK---------------
>UniRef50_Q7UA92(443-760:768) Phosphoribosylformylglycinamidine synthase 2 n=8 Tax=Cyanobacteria RepID=PURL_SYNPX  E=2e-16 s/c=0.28 id=18% cov=71%
-----------------------------------------------------------------------------------LSCVGAEPLAITDNLNFPSPETPKgywQLAMACRGIAEACRALNTPVTGGNVSLYNETRRDDgtlqpihPTPVVGMVGLVENiERVVGLGWRQPGDAVLLLGvapdeqgddRLGLAGSSYQMLVSGVLAGRPPRVDFeleRGVQQLLRQAIDAGLLASAHDSSDGGLAVALAESSIASSLGVELKLNGRP--EGLTR----------TLFAEGGARVAISVKAECRPQWDQLAAESTVPITELGVVNDGSTFRIHC---GEKDVQWSLADLkrahqegLPR--
>UniRef50_C6XIX6(5-315:323) Thiamine-monophosphate kinase n=1 Tax=Hirschia baltica ATCC 49814 RepID=C6XIX6_HIRBI  E=9e-37 s/c=0.50 id=19% cov=88%
----------------DLIKTYFAPLAISPDAFGLKDDV---AALNPPAGRQLIITTDTLVESVHFLsedPLETVAQKLLRVNISDVLAKGGTPWAAVLSLTWPSGRDVRQLSSFADGLKADLEHWGISLMGGDTTSTSGPLTLGLTLLAHC----PQTGPILRSGGKQGDDIWVTGSIGDGYLGLKAAMGELSLsrpeDVALLAWRYRVPEIPDSAIAelISEVAHASADVSDGLVADINHIAKASNLQAIINLDEVPFSSAAKLCLAEKKVSRLELvtkGDDYQSVFTAPPEAKAVILRA--SLQYGLEITKIGTMQTGQGVSLQRPNGTM---------------
>UniRef50_Q1DAT6(15-345:352) Selenide, water dikinase n=6 Tax=Bacteria RepID=SELD_MYXXD   E=1e-36 s/c=0.47 id=25% cov=68%
-----------------------------------------------------------------------FGAIAAANALSDIYAMGARPLFALNLVCFPDELPLKVLSKILAGGQSKADEAGIPILGGHSIRDP-----EPKFGMAVTGVVHPKKVLTNAGAKPGDVLFLTKPLGSGIATTAIKRGvaSKQLAKRALGVMTTLNRAAGEVFASGkfKVNALTDVTGYGLLGHLLEMMTAAKARATLDLERIPLIAEVPALAEDgvvpggtksnlahvhkkvrfpegLPECIQWVLADaqtnGGLLASVPARQALKALKALEAA--GVDAALIGEV------------------------------
>UniRef50_Q0ATX4(8-311:315) Selenophosphate synthase n=1 Tax=Syntrophomonas wolfei subsp. wolfei str. Goettingen RepID=Q0ATX4_SYNWW  E=2e-36 s/c=0.51 id=21% cov=69%
-----------------------------------------------------------------------FGQIAATNALNDIYAMGGTPILALNVVCFPECADLQVLRKILEGGLSKVLEAGALLVGGHTVDD-----NEPKYGLAVSGLVHPQKIIANNGAQPGDLLFLTKPLGNGviATSIKAEMVSGEAYKEAIKWMSMLNRESSQAMMEVGVNAATDITGFGLMGHLYEMAWGSDVQVEVFADKVPFMEGTLEYAGLglipggaynnrdylkdkveyaGNIDPLirdlffSPETAGGLLIAVAEKKAGELLQVMEKR--GSFCNLIGRVRGEH--------------------------
>UniRef50_A6G515(16-355:357) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G515_9DELT  E=8e-36 s/c=0.45 id=22% cov=70%
--------------------------------------------------------------------------------VNDLLCTGGRPLFVLDYVA-TGRLEPGKIEQIVAGVVAGCRQSNCALIGGETAELPGMYADGhYDLAATAVGVVDKASIWAPSRTQAGDVILGLASSGLHSNGYSLARKALlspehgamtlddplpgsggSVGEALLEPTRIYEPAFAALRALEGaaVRSAAHITGGGLIENPPR-AYGEQLCAEIDLSAVEVPAVLRAIAEvgVARNELLKTFNCGvGMLLFVDPERVDEVSTAC--EGAGQPVARLGQVVArdsasGDAVRIRGGLG-----------------
>UniRef50_B7H4T6(65-374:739) Phosphoribosylformylglycinamidine synthase 2 n=87 Tax=Bacteria RepID=PURL_BACC4  E=1e-35 s/c=0.49 id=22% cov=69%
----------------------------------------------------------------------------VGGIIRDVFSMGARPVALLNSLRFGELQSPRVkylFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPL-VNAMCVGLINHEDIKKGQAHGAGNTVMYvgasTGRDGIHGATFAseelSESSEAKRPAVQVGDPFMEKLLIEACLELiqsDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRE-----TGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEK--YGLAAVTMGKVTEDKMLRL----------------------
>UniRef50_Q6LH23(22-322:323) Hypothetical selenophosphate synthase n=2 Tax=Photobacterium profundum RepID=Q6LH23_PHOPR  E=1e-35 s/c=0.51 id=20% cov=52%
----------------------------------------------------------------------DFGAIAAANALSDVYAMGGQVTLAMNIFCVPVDLPQEVVGQILKGGADKVREAGAVLVGGHTVED-----DEPKFGLSVMGMIHPSKVQTKAAVESGDILVLTKPLGTGVISTAAKRGKASQESIQTSTdsMKKLNRNAAQIFVKYPIKACTDITGYSLLGHALEMAEKSDVCMHFIADQVP--------------------------------------------------------------------------------------
>UniRef50_Q18JI5(60-367:725) Phosphoribosylformylglycinamidine synthase 2 n=8 Tax=Halobacteriaceae RepID=PURL_HALWD  E=1e-35 s/c=0.50 id=21% cov=72%
----------------------------------------------------------------------------VGGIVRDTLSMGAYPIALADSLyfgSFDRERTQYLLDGVVEGIADYGNAIGVPTVAGSVEFHNKYTGNPL-VNVACIGLLTDERLVTAEAQSPGNKLVLvgnaTGRDGLGGASFASEDLSEDAETEDRPAVQVGDPYTekrlieanEELITAELIQSARDLGAAGLGGASSELVAKGGLGARINLERVHQREPAMNAMEI-----LLAESQERMCYEVHPDDVETVGDIAAKYDLG--YAVIGEIRDGNYV---CTFGDETVVDVPAG-------
>UniRef50_O28339(95-383:765) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Euryarchaeota RepID=PURL_ARCFU  E=2e-35 s/c=0.53 id=23% cov=67%
------------------------------------------------------------------------------GILRDVLCMGAQPIALIDPLFfgnldtpyekLPRGTkhPLYLLKGVVAGIRDYGNRVGIPTVAGMVFFDNSYLTNCL-VNVGCVGIVRKDRIIHSRAGGAGDLFVLaggkTGRDGIHGVTFASAELDEKSEEEARGAVQLGNPIMKeplihaclEVVEKGLLTGMKDLGGGGLSCVIGEMALAAGFGAEVYLDKVPLKEEGMAPWEI-----WISESQERMMLTVRPEHIDEVLYIFQK--WDVPATVVGKVIPEK--------------------------
>UniRef50_O28339(463-735:765) Phosphoribosylformylglycinamidine synthase 2 n=4 Tax=Euryarchaeota RepID=PURL_ARCFU  E=1e-16 s/c=0.33 id=25% cov=22%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VKACHDVSMGGLAVCIAEMSFGRGLGF--------------EAARELSFVELFSESNTRWVVEVPESVAEGYAEFFRAKEL--KAEVIGY-------------------------------
>UniRef50_B5YF24(54-356:361) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Dictyoglomus RepID=B5YF24_DICT6  E=2e-35 s/c=0.50 id=19% cov=68%
--------------------------------------------------------------------------------VNDILTAGAKPLFFMDYFA-GGRIDPEVYKKVLVSIANACKKADCSLVGGETAEMPGvYKGKEIDLAGFVVGIVEEENLLPKMGkIQEGNILIGVSSSGLHSNGYSLIRYilkkkrisirkkidGHDLLEELLKPTKIYSPVILPLLEKYRdnILGIAHITGGGIPGNLPRILPG-HIQAEIDPSLWEIPwifKFLIKKGNLTWKEAFKVFNMGiGLILIVS-ERENEILEDLKN--SGEKAYVIGSLSKGER-------------------------
>UniRef50_D1N977(27-347:347) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Victivallis vadensis ATCC BAA-548 RepID=D1N977_9BACT  E=2e-35 s/c=0.47 id=20% cov=70%
-----------------------------------------------------------------------VGHDIVNHCIDDIAVQGAEPVYFMDYIGI-GKLRSPLYEEVLTGIADACKAANVAVLGGETAEMPGMYGNDFDLVGVITGIVEKSKMITGEKIRPGHVAIGFGSNGLHTNGFSLARKilfsqcsynvrtyldelGETVGEALLKPHTSYYPAIREAQERGlALDGIAHITGGGLYDNVPRILPE-DVTAVFKTDVLPIPPIFKVLVEKGHVDPieaYRVFNMGvGMVWFVPANAADEAVEIGRSKGFTTG--IIGEIIPGH--------------------------
>UniRef50_Q0C317(4-289:317) Thiamine-monophosphate kinase n=1 Tax=Hyphomonas neptunium ATCC 15444 RepID=Q0C317_HYPNA  E=2e-35 s/c=0.53 id=22% cov=72%
------------------IRQYFAPLAKAPGAAGLTD----DTAEISKGYGPLIATVDAMVEGVHFFaddPVETIARKLVRVNVSDILGSGAVPREALLTLGWPQaGRNPGQIGTFADSFGTELDRWGILLAGGDTVMTPGG----LFLSLTLTGECLGPAPVRRGGGKAGDDVWVTGEIGAARRGYLWKTQGLGEAGWLNALQVPELPPLEAAGLISAHASAAMDISDGLLGDLSSLAAASGLGAQIDLDQVPFAGGAASLEEMIDLSSW---------------------------------------------------------------------
>UniRef50_C9RLV8(26-321:328) Thiamine-monophosphate kinase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RLV8_FIBSS  E=2e-35 s/c=0.51 id=26% cov=71%
--------------------------------------------------------------------------------VSDVSSMGGRPKIALFGLCVNKNWSEETRNRIAKAVAQGFERRGITLIGGDTVSGDVG-----MFSTTLLGTTDGEISLLRSDAKPGDHVFVAGTLGKSDAGlwiLMNHPEEANRFPRLVEYHLAPKICEDAGAQLvkQGVRGACMDISDGLSSETNHLALSSGVSIEIDEQKLPIDPDVLEMCEYFGLSPLQfalnGGEEYELLFT---SNLTKSI-YLEGAPKMGEIHDIGLVSCGNGVYLKGQDGVKALLN-----------
>UniRef50_B9LT08(47-355:759) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Halobacteriaceae RepID=PURL_HALLT  E=3e-35 s/c=0.49 id=22% cov=48%
------------------------------------------------------------------------------------------------------------------------------------------------VNVACVGLTNEDRLVTATAQEPGNTLMLvgngTGRDGLGGASFASEDLAEDAETEDRPAVQVGDPYAekrliecnEALVDEDLVLSARDLGAAGLGGASSELVAKGGLGARLDLDSVHQREPNMNAMEI-----LLAESQERMCYEVAPEDVARVEALAERFDLG--CSVIGEVTDGNYV------------------------
>UniRef50_B8GIC4(37-358:693) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Methanosphaerula palustris E1-9c RepID=B8GIC4_METPE  E=4e-35 s/c=0.47 id=16% cov=85%
-------------------------------LGPGDDAAIVSFSETC----ALAIGMESHN-HPSYVDPYDGSATGVGGIVRDVISMGAKPIALMDPLYFGPLTDEKnryLFSHVISGISGYGNCIGVPVVRGEVVFDEGYSGNPL-VNVVCVGTVDPTKYLTARVKVPGNHLVLvgarTGRDGLGGASFASRDIAEDAEAVDRPSVQIGDPFTEkliidamlAMAATGKVLSCRDLGAAGLAGASSEMCSTFG--GIIHAEKVHLRE-----TGMTALEIMLAESQERMLLEVAPEDVAQIGSL--AERFDLCWSDIGEVTSDPRYVVD--FHGEVVCDLPIDLLIdgaPR--
>UniRef50_A3IWC4(430-754:765) Selenide, water dikinase n=3 Tax=Cyanobacteria RepID=A3IWC4_9CHRO   E=4e-35 s/c=0.46 id=20% cov=78%
-----------------------------VGLASPDDAAIIDIS----EQELLVETIDYF---PSFIsDPFVFGQITTNHCLSDLWAMGAKAHSVSAVITLPYGVDsvlEEILYQLLEGCLKILKQNQVSLVGGHTL-----QGEKLGFGLSCNGFILPNRILCKSGMQPNDKIILTKPLGIGtllAAEMIYQTKGNWIDNAIQSMLIS-NKKASEIFLQFEASACTDITGFGLVGHLIEMMKASQVSVELNLDKIPILIGAIETIKQgitsslhpknldnetyltvnknikkspnysLLFDPQTS---GGLLASIPEENADRCLQELIRAGY-TDSQMIGKVI-----------------------------
>UniRef50_B8GHC5(4-281:291) Thiamine-monophosphate kinase n=1 Tax=Methanosphaerula palustris E1-9c RepID=B8GHC5_METPE  E=8e-35 s/c=0.54 id=26% cov=67%
-----------------------------------------------------------------------IGWMSAAVTISDIASMGATPCWLLLAAGLDRG---ERLAGITAGAYACCERFGCRLVGGDT-----DHHEELTVVTTGIGAVMPDRVVRRQGSRAGDLICMTGVPGEAEAGLHGFKQHW-------YTLIEPQPRVAEGQAIGraGASAMMDVSDGLALSLYDLQTANPSVGYTIRSRLLRRPAGVP-PAEGLEL-ALFGGGDFELLFTCAQDRYP---------IAGVDATVIGAVTDQPGVLLDGEVLEKR--------------
>UniRef50_Q9HJA4(65-384:759) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Euryarchaeota RepID=PURL_THEAC  E=2e-34 s/c=0.47 id=19% cov=71%
------------------------------------------------------------------------------GIVRDVLCMGAQPVALIDSLFLGDvssdryeglLSPRYIFGGVVGGIRDYGNRIGIPNVAGSLYFDKLYNSNPL-VNAGCVGIVRRDRIVRSKSYKPGDVLVLmggkTGRDGIHGVNFASTTLGKVTKSSRLAIQlgnpiveQPMIKAVLEANDAGLIRAMKDLGGGGLSSAATEMVYAGGFGAEITLDDIKLKE-----SNMSGWEIWISESQERMLMECYPEDVEKIRQI--AEKWNLDFSVIGQVTADRRIRV--YYKKRKIIDM----------
>UniRef50_C3N674(42-352:709) Phosphoribosylformylglycinamidine synthase 2 n=12 Tax=Sulfolobaceae RepID=PURL_SULIA  E=2e-34 s/c=0.48 id=20% cov=90%
-------------------SKIFLKSFsiDSPNVIMGIKDWQDAGAVDIGDGWAIVIKVESHN-HPSAIDPFNGAATGVGGIIRDIISKGAKPIALMDMIRVGNlkiRKNVWLLKNIIAGIAAYGNSIGVPVVGGELSFDDTYN-DNPLVDVAAIGIVRKDKIKPSIVDKAGLKLVLAGLTGIDGLGGASfasrkLSGEDEIGAVQIADPFAGKIILDITLEIAdKVEAIKDLGGGGLAVAVTEMAN--GLGAIVDIEKIPLR-----VKNMNPADVIISETQERMLYAVEEKNVEEVCKAFEEYEY--PCSVIGEITSEP--IIKFRYFGKDLVSLPTNALL----
>UniRef50_C3N674(385-688:709) Phosphoribosylformylglycinamidine synthase 2 n=12 Tax=Sulfolobaceae RepID=PURL_SULIA  E=2e-14 s/c=0.27 id=19% cov=55%
----------------------------------------------------------------------------------------------------------------IRGIGEATRFFNIPIVGGKVSFYNENSQGKPIKPTpliVMAGLV-QGKLLKNRVEDSSYVVLLGYTRKELGGSLLSKIFKVPSQApkvRLQEDLLSSEVVIDAINE-EKITFAKDISRGGLAASLfNIIVHGYGVEISTKSILSDTDNVV---------ENLFSESSGRFVILTNE--PEWIVE--KSRSKGIVASIIGKVNKKTSI------------------------
>UniRef50_B8D423(23-334:339) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D423_DESK1  E=4e-34 s/c=0.47 id=17% cov=86%
-----------------------MHRYVLERMGKLDDRGIEPYGSfsqwVTVDGKAIALHIDGVGTKTIVLKKLGklrvAGWDCVAVNVNDVACDNVEPVALLDYIALPSS-DTDSFREIIDGIMDAAGELGVKLIGGETAIMPDL-VNGIDVVCMVIGYKKGS---GRYRARVGDLVIGVNSWGLHANGYTLARKivestlgsydavidGVNIGKELSKPTPIYSRLVLEALGSGYASAAAHITGGSFYKAKRILPGEADMVIKAPEPP-PIFKVLMKLGNVSPPEMYRVFNMGiGLVLTTSRDNLDGLSRLIEEH--GFHPYVIGEIVEGNGLVhVITPYG-----------------
>UniRef50_A4A0I2(4-296:305) Thiamine-monophosphate kinase n=1 Tax=Blastopirellula marina DSM 3645 RepID=A4A0I2_9PLAN  E=4e-34 s/c=0.50 id=21% cov=83%
----------------EFIQHLRKSLGSHDRLriGLGDDAAILDW----RDRDDLVVTTDLISDEIDFRlaevDPRRVGRKALAVNLSDLAAMGAEPVAVVVSLLLPRtppvGTALELAVQLYDGMLPLVEQFDCILAGGDTNSWSG----PLAINVTAFGSC-SDQPLLRRGAAPGDVILVTGELGGSILG-----HHFDFTPRIAE--------ARRLTRLGLAQVGMDISDGLLLDL-SRLLNESEVAGVLDLTSIPISDAAHRLSETSGRTPLEHaladGEDFELLLTASPEHAQQIVAD---DLLGTPVTAIGKIVAGAGMWADQVGGKK---------------
>UniRef50_D1BR39(12-340:343) Selenide, water dikinase n=3 Tax=Veillonella RepID=D1BR39_VEIPT   E=5e-34 s/c=0.45 id=19% cov=55%
-----------------------------------------------------------------------FGKIAAANALSDVYAMGGTPLTAMNIVGFPvPLVEQGVLTDVLNGAGSIVAEAGAAIVGGHSIEN-----KEPIFGMSVTGQVNPKQIWKNKGAQIGDVLVLTKRIgtGIMNNALKAGLFPVGTEQAVTS-MSTLNRVAAEVAHNFTVHACTDVTGFSLMGHSVEMASASDVTIHIKAYDIPLFDDVIEAAQM---------------------------------------------------------------------------
>UniRef50_C0Q953(5-346:349) SelD2 n=1 Tax=Desulfobacterium autotrophicum HRM2 RepID=C0Q953_DESAH  E=7e-34 s/c=0.43 id=20% cov=80%
-----------------------------VGLERADDAGVYKVS----DDLALIQTVDFFT--PIVDDPYWFGQIAAANALSDVYAMGGTPKTAMNLVAFPvKEMDISVLRQIIQGGIDKLVEAEVVLLGGHSIED-----KELKYGLSVTGFVHPQKVLIKGNLNPGNQLILTKPLGTGiiNTAIKAAMASQALTDTVTRLMATLNRQAADIMSGFDVTACTDVTGFGLIGHLAEMILGSGMTVRLFSKNVPVIQEALTFASMGLIPAgayknrefretmtQFSGNvdqslqavlvdpqtSGGLLISVKASQASQLLSALKNAGIS-DAALIGEVIDG---------------------------
>UniRef50_A1ZMQ5(58-369:755) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Microscilla marina ATCC 23134 RepID=A1ZMQ5_9SPHI  E=2e-33 s/c=0.46 id=23% cov=22%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMSAKGEHGMDIDLDKVPLRQE-----NMLPFEILLSESQERMLVVVEKGKEQEILDIFDKWDL--NCAEIGTVTESNNVR-----------------------
>UniRef50_C1F5Y2(443-768:785) Phosphoribosylformylglycinamidine synthase II n=3 Tax=Bacteria RepID=C1F5Y2_ACIC5  E=6e-24 s/c=0.35 id=19% cov=69%
---------------------------------------------------------------------------AVAEAARKVACTGATPVAATNCLNFGNPEKPEIMAQLstaIDGMAEACTALGTPITGGNVSLYNETRGEGIYPTpvIGVVGILDDvTKSVPAHFQRAGDLVYLVGGKSIAGAignalhtfgATEYARQRFahlwgDVPALHLDDEAALHRALAELAQASAVQSVNDVSDGGLAVALAKNCFPRQIGVRVEvSDPTGTPPEMMLFHEDASL----------VVASVAPEKKDDFLRIIAAHAQ-LFAVQLGETVKQRFTILRN--------------------
>UniRef50_C4LH52(133-428:862) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Corynebacterium RepID=C4LH52_CORK4  E=7e-33 s/c=0.48 id=20% cov=28%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLSCATSELAAAGDGGMEVNLDAVPLRAENMTAAEI-----LSSESQERMCAVVTPENVDRFREIC--AHWDVTCAEIGEVTDGDHLVIR--HHGQVVVDAPA--------
>UniRef50_C4LH52(485-839:862) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Corynebacterium RepID=C4LH52_CORK4  E=3e-20 s/c=0.28 id=20% cov=84%
--------------SRAFITEQYDRYVmGNTVEAQNADAGVLR--IDESTGRGVAVSADASGRYTKLDPNMG-ARLALAEAYRNVVVTGARPVAVTNCLNFGSPEDPAVMWQFreaVHGLADGARELGIPVSGGNVSFYNQTGSEAIlptpLVGVAGVvtsvdhhinhllgGLTTERSAFPESESDAGDDssastsgsandqfeeLYLLGETHDELGGSIWQQVKHNALSGLPPqvDLAATSALADFFCDQADpdtprvVTAAHDLSEGGLAQALAELAMISGVGMDVDVSKVHADPCV----------ALFSESANRVVVACAHGDGDKLVSLAKR--CGIPVLRLGSVTSR---------------------------
>UniRef50_A7I780(45-319:338) AIR synthase related protein n=6 Tax=Methanomicrobia RepID=A7I780_METB6  E=9e-33 s/c=0.52 id=17% cov=66%
----------------------------------------------------------------------------------DIAAMGGRPIAMVDVFSMPKNTHIH--EQVVKGMHDASAQFGVPIVGGHLHPDAPYS----VIDVSILGSARLDSIIYSNTAQEGDHILAAIDLSgrVHPSCALNWD---SVTMKTAAYVRAQIALLEEIGKDHLVTAGKDISNPGLIGTLGMLLEVSGRGAEIDLGKVPKPD--LAANAMTFEQWVKMYPGMGFILTARKQNVDELVRRFAA--VGMTAHDIGTVDATRRLRIR---------------------
>UniRef50_C0EUP9(4-364:373) Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM 3353 RepID=C0EUP9_9FIRM  E=5e-32 s/c=0.39 id=22% cov=91%
-----------GKVKESILKRSVLRQLHNHSEkgspAPGEDAGVLFMPEFMPeftqgfsGKNGVAMAVNP-VEGWTF-----AAKRAVYGAVNSMLAAGAAPKAISLSILMPEEAEEKQLKALIKEIDSLCMQENILVLSGHTAVSP--YVSTLILSVTAMGsttenrkditankgsitrnkesiLVSKESIADSKGntkqIAVGNadlDLVVAGTVGREGAAMLAAEYAKRLEERyapsYVEAAKHLFDdgsmtAVEDILQEKEVVSVHDVREGGIFAALWEMAAAANVGLSIDLKNIPIKQHTIEVCEYFNLNPYMLRSGGTLLLACA--NGARIVEQLQKA--GVAAAVIGQTTSGNDRLIRYDDEA-RFLEPPKMD------
>UniRef50_Q99611(108-428:448) Selenide, water dikinase 2 n=28 Tax=Coelomata RepID=SPS2_HUMAN   E=2e-31 s/c=0.43 id=24% cov=62%
----------------------------------------------------------------------------------------------------------------VKGFRDAAEEGGTAVTGGQTVVNP-----WIIIGGVATVVCQPNEFIMPDSAVVGDVLVLTKPLGTQVAVNAHQwldnperwnkvkmvvsREEVELAyQEAMFNMATLNRTAAGLMHTFNAHAATDITGFGILGHSQNLAKQQRNEVSFVIHNLPIIAKMAAVSKASGRFGLLqgtsAETSGGLLICLPREQAARFCSEIKSSKYGEghQAWIVGIVEKGNR--------TARIIDKPRViEVLPR--
>UniRef50_A5Z7T1(4-317:319) Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum ATCC 27560 RepID=A5Z7T1_9FIRM  E=2e-31 s/c=0.44 id=19% cov=72%
-------------------------------------------------------------------------------SINSICEKGGVPKSLQLSITMPLEFEEKEVNRMIKNFRKSADSHNVEI---NQCNVYRGTTEGPIINIFMIGTT--GNLLKSDSIKPGMDVIMAGTLAIGGTSVIAERYKDKLEgkfsGRFISECLELKDYtstekASAIAIDAGAVYMHAVSEGGLFSGLWEVASCVDKGIQVDINKIPIWQQVIEIAEFMDINPYLLEGSGSLLI-VSPDGY-KIEESLNAN--GIYGEVIGKITDNKNRVVINGDET-RYLEPPRGD------
>UniRef50_D1J913(20-322:334) Putative uncharacterized protein n=1 Tax=uncultured archaeon RepID=D1J913_9ARCH  E=4e-31 s/c=0.45 id=18% cov=71%
------------------------------------------------------------------------GYCAVLVNVADISAMGGTPLAM---VNLTSTQEKGICAELGQGMADGVRKFGVPMVGGHLHPDTNYDA----LDVAIMGTVKRDCVIFSSGAKPGDKVLVAIDID----GGIYPSYNLAWDNTTRRTVAEIKKQLDTMVEIGekkLATAGKDISNPGTLGTFGMLLESSGAGAVVELDKIPRPD-----LDIPFEQWLKMYPGTGFVLTVENDDnAAECIRIF--EDAGVATSIVGEVDASKKLKITNGTETATVFDL----------
>UniRef50_Q9RXT4(418-721:747) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Deinococci RepID=PURL_DEIRA  E=2e-16 s/c=0.29 id=21% cov=68%
---------------------------------------------------------------------------AVAEAARNLACVGATPLAITDNLNFGNPHRPEVyyqLQQAVQGIADACRALNTPVTGGNVSLYNQYTEGDhkvaihPTPTIGMVGVLPDVTVRASLNLKaAGQTLLLLGhraekgwSDSIGASQYLETVHGLEAGQVPPVDLDLAQKVVDgtlALIRAGLTDTAHDCAEGGLAVALAEMAIAGGLGLNVSLDAPaSVRADALLFGEAHSRVIVA--------------VEDAAAAGAKLDELGLPYAVLGETVEAPKVTIAAP-------------------
>UniRef50_O67691(416-715:745) Phosphoribosylformylglycinamidine synthase 2 n=6 Tax=Aquificales RepID=PURL_AQUAE  E=4e-25 s/c=0.39 id=18% cov=52%
------------------------------------------------------------------------GKFVVAEVCRNLACVGAKPLAITDCLNFGNPERPEIMWQFVKaveGMAEACEELGIPVVSGNVSLYNETVEKNeirnvfPTPIVVGVGVLEKAEKYTPSKVEKESELYLVGnleeNLRLDGSEYLKVIHGLikgDVPPVDLEKEKILINLLISFNNKELITCAHDVSVGGLLIALLEMVFRTPYGLEVE-------------------------------------------------------------------------------------------
>UniRef50_A7GYY9(55-352:729) Phosphoribosylformylglycinamidine synthase 2 n=2 Tax=Proteobacteria RepID=PURL_CAMC5  E=3e-30 s/c=0.45 id=20% cov=25%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLTSSSFEMAGRSGSGMKMQLDRVPMREE-----GMSPYELMLSESQERMLICAKKGCEQKVLEIFKKWDL--DAEVIGEVTDSGQMQL----------------------
>UniRef50_B3E7F7(4-260:346) Selenide, water dikinase n=7 Tax=Desulfuromonadales RepID=SELD_GEOLS  E=3e-30 s/c=0.53 id=22% cov=54%
-----------------------------------------------------------------------FGRIAAANALSDIYAMGGRPLTAMNLAFFPAcSLQPEVLGEVLAGGQDALNEAGCCLVGGHTVED-----DELKYGLSVTGTVHPEQVLRNSTARPGDCLLLTKPLGSGilSTAVKGEMATVEQEAEAVAWMSLLNRAAAELMLRYTPSACTDITGFGLIGHSCEMALGSGVTIRLYLDAVPLMQGV---------------------------------------------------------------------------------
>UniRef50_B4WLV7(428-776:784) Selenide, water dikinase, putative n=1 Tax=Synechococcus sp. PCC 7335 RepID=B4WLV7_9SYNE  E=4e-30 s/c=0.38 id=18% cov=78%
------------------------------GLDQPDDAAIIQ----IPSGKLAVHTVDQFSA--LVDDPFVFGQICVNHCLSDLFAMGATSHSVLAIATIPYGNNkqqEEILYQLLSGAMLALAESKTFLVGGHTT-----EGTELSLGFSCNGWIDPEQTWKKGGLQPGQALILTKALGTGvlfAADSQLKAKGRWIEAAIQSMLQS-NRMAAECLKQYGATACTDVTGFGLAGHLLEMVQASQVVVGLNLNAIKLLSGTEYALKngitsslyqrnlenalsaiqttqpveqtaihapdfQILFDPQTA---GGLLASVPANSVDECLSTLHRLGY-RDSRYIGNV------------------------------
>UniRef50_UPI0001C30E92(443-732:752) phosphoribosylformylglycinamidine synthase II n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C30E92  E=5e-21 s/c=0.36 id=21% cov=62%
----------------------------------------------------------------------------------------------------------------VRGMADACRALDTPVVGGNVSLYNEGGGGPIYPTpvVGIVGRLPDAARAGRLGfAHAGDAIAVvrAASPSLAASELAKLRGEalpDGLPERSLPALRAAIELVRDAVRRGDLRSAHDVAEGGLAVALAESALAGGNGARVDLA----LVGGATCQSLPLDEQLFGEGPGTFVLSGPRAALDA---LAAAAPEGVAVSVVGEV-GGDALAVEHGGGT---LAWPLADL-----
>UniRef50_A0B908(89-396:456) AIR synthase related protein n=26 Tax=Archaea RepID=A0B908_METTP   E=6e-30 s/c=0.44 id=19% cov=91%
------SRGLGDFYMHTKIAEVIGRTGAVVDSSQLDDSGVVKAG-----DKYLIVTVDGMHSRLSDYP-FLAGFHVTRAALRDILVMGARPVALFSDIHLADDGDVAKVLDHIAGIATVGELVNVPLITGSTLRIGGDMVIGDRLTGCVGAVGIAERITPRKDAAPGDVIIMTEGAGGGTICAAALYYGMHDVVEETLNIKFLEAAGALIDEGPEIHAMTDVTNGGIRGDAKEISHTAGVKMVFFEERMRslVNHRVLEMLERLEIDYLGVSID-ALLIIAPEREADVILGVIEKA--GVAADIIGRVERGSGVELHTKEGIK---------------
>UniRef50_Q0BZA9(405-728:728) Pyridine nucleotide-disulphide oxidoreductase / selenide, water dikinase n=35 Tax=Rhodobacterales RepID=Q0BZA9_HYPNA  E=8e-30 s/c=0.41 id=23% cov=80%
------------------------ALHADTITGAGDDAAVLRSGARLQ-----VISTDhlrAFVDDPYL-----MARIAAVHALGDVCAMGAAPQSALLSLIIPrmsDPMQKATVAEVVAAVSDVLRAAGADLVGGHTSM-----GRELTIGLTVTGLLDGP-AIGLTGARPGDAILLTKPLG-TGVILAAEMRGLARGKDVEHALASMQRPLAAAskILAPAAHAMTDVTGFGLAGHLMSILEASDVSARIALPDLPVLPGAEQLSaqgirsslwqsnasleprisrpaspiSDLIYDPQTA---GGLLAVVPSQSVTGLLSAFQAE--GEPAFVIGRIEEGPPRIL----------------------
>UniRef50_Q31DG0(1-306:328) Thiamine-phosphate kinase n=6 Tax=Prochlorococcus marinus RepID=Q31DG0_PROM9  E=1e-29 s/c=0.43 id=17% cov=29%
----------------------------------------------------------------------DLGWKAVVSNISDLLSSGSKKtIGITISLILPAKTEWVWVEELYKGINKALKEYGGKILGGD-----CSKGNQKTISITAFGIQ-GELELRRNACKPGDIILTTG------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C3XH11(64-380:798) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Helicobacter bilis ATCC 43879 RepID=C3XH11_9HELI  E=3e-29 s/c=0.41 id=16% cov=25%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GLTSSSFEMASRSGSGMIMWLDKIPMRE-----SGMTPYELMLSESQERMLLCAKKGTEKQIKDIFAKYEL--SAEIVGEVRNTGKMEL----------------------
>UniRef50_D2PDK4(9-298:316) AIR synthase related protein domain protein n=9 Tax=Sulfolobus RepID=D2PDK4_SULIS  E=5e-29 s/c=0.45 id=16% cov=84%
---------------HEFIKRYIKNYVDIKLL---DDVFIHEKRGYKVDGFKLSYT-------FPFMSLYDIGWKAISASTSDIIAKGVKPEFYLISLGLPPDFDVNKAEELIKGISDAIHYYGGRYIGGDLNDSDSSG----WVDVFVEGEVLCD--ISNKDIDDGDLLVVGDYIGYTTNVFISYINNFNIQILPESLLKVKHPIVRKsllffMKKYCKFIKYSTDISDGLMVSLYKIIDNFDLGINITEIPIdkNVFNTLKLRLNLTELDILkHAGEEFLPLLIIDKNSpVKEMLNELQ--YLAFNPLIIGQVIHEKKVVI----------------------
>UniRef50_Q8UEB0(92-401:775) Phosphoribosylformylglycinamidine synthase 2 n=86 Tax=Bacteria RepID=PURL_AGRT5  E=3e-28 s/c=0.41 id=23% cov=34%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELMKTGAVIAIQDMGAAGLTCSAVEMGAKGDLGIELDLNAVPVREE-----RMTAYEMMLSESQERMLMVLEPSKEEVAKAIFVK--WGLDFAIVGKTTDD--LRFRVLHNGEEVANLPIKEL-----
>UniRef50_Q8UEB0(460-750:775) Phosphoribosylformylglycinamidine synthase 2 n=86 Tax=Bacteria RepID=PURL_AGRT5  E=1e-21 s/c=0.36 id=25% cov=27%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAVHDCSSGGLALAVAEMAISSGIGATID-----------AVEGHNPILTFYGEDQARYVLTVKKSDLDKVRAAAKAA--GVSCPLIGT-TGGSTVKL----GTARAVE-----------
>UniRef50_UPI000050FADA(10-350:362) thiamine monophosphate kinase n=1 Tax=Brevibacterium linens BL2 RepID=UPI000050FADA  E=3e-28 s/c=0.38 id=22% cov=62%
-----------------------------VIIGPGDDAAV------TAVDGNLVSTADMLVENEDFtrtwLDWSRLGTKAAAQNLSDVCVMGAKPHGLLVSLAVPNSTEIEDLEALFAGIVAEAARAGealgceIPIIGGDLS-----SSGLIVVAITALgtvggsgtgtaassaGTHGSGAAITRAGAQPGDSIYLAGTIGRAAAGLDLLFAGVDPNAdvgqddpqpgtsltELINTQLAPQPDYAAVLEMRAASAMIDVSD-GLSTDLGRVAAASGVHACIDRTA----------------------------------------------------------------------------------------
>UniRef50_C7M1V9(46-340:734) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M1V9_ACIFD  E=9e-28 s/c=0.43 id=22% cov=66%
----------------------------------------------------------------------------VGGILRDIFTVGARPIALLDSLWMGPQDDArsRWItDGVVGGISAYGNAVGVPTVGGELRVDACYGANPL-VNVVAVGVAPTEALVRARAEGIGNYVVLLGaPTGRDGIGGVSVLASAGFDATAEqkrpsvqvGDPFEEKKLIEaclALMRAGLVTGVQDLGGAGLTCATSETAAAAGVGMDIFLDAVPRREP-----GMTPMEVLCSESQERMLAIVEPGLLDEVIATCRRFE--VTASVIGVV------------------------------
>UniRef50_C7M1V9(424-714:734) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M1V9_ACIFD  E=4e-15 s/c=0.29 id=21% cov=31%
--------------------------FRTSLVEPGADAALLRVRTPEVGdtGRAIAITVDGNNRWTRVDPRHGATWL-VAEGVANLACVGATPLALVDCLNFGNPEHPTVMWQLaesIDGIAEAARALGVPVVGG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_O27569(91-415:462) Hydrogenase expression/formation protein HypE related protein n=8 Tax=Euryarchaeota RepID=O27569_METTH  E=2e-25 s/c=0.36 id=23% cov=72%
----------------------------------------------------------------------------------DVCVMGSRPVALISDLHLADDGDVGKLFDFTAGVAAVSELVGVPVVAGSTLRVGGDMvlGDRLVSAVGAIGFSETP-PTARKRAEPGDVILLTEGSGGGTITTTAIYHGLfdvVWETLDVNFIRASEAIMDSGL-LGDVHAMTDVTNGGLRGDAHEISSTAGVGLEFDADAvmSMINPSVLRMLQDLEIDPLGVSID-SLMIIAPEDVAPDVMDTIRGA--GVDVAEIGRVTD-SGVPVLLRDGSEEELRPLFRE------
>UniRef50_Q3ZZB9(266-555:953) Phosphoribosylformylglycinamidine synthase II n=7 Tax=Bacteria RepID=Q3ZZB9_DEHSC  E=2e-25 s/c=0.41 id=22% cov=45%
-----------------------------------------------------------------------------------------------------------------------------------------------------IGLIPKKYALPGKQ-SAGDLVVLiggrTGRDGIHGVTFASGELNDRSTELSFTAVQIGNAIVEKrmldtllqARDRELFVRITDCGGGGLSSAVGEMAESTGV--KIYLDKVPLKYSGLTYSEI-----WISESQERMLLAVNKEKLGEILALFESE--GVEASVIGEFTSD---------------------------
>UniRef50_A7VEH2(3-314:314) Putative uncharacterized protein n=1 Tax=Clostridium sp. L2-50 RepID=A7VEH2_9CLOT  E=3e-25 s/c=0.38 id=17% cov=67%
---------------------------------------------------------------------------------NKLRLGGYQPFALTDTVMMPEN-DEKRMKKILRELSDLAKEFHMDVVYGDTAIS--GIFKEPAVTVTMYGrRISQGE--KNAKIKPDMDIVMCGQAGILGTLLRVRERKEELLTRYSEEYLRtaeQFDRLLLVKDQGDIAMACgsiyvrHISTEGVYGALWELAEAGNVGLRISHDHIPIMQETIEICEFTGDDPYRIDGCGAALFVT----ADGGLLSDRLYEAGFEAAVIGRTTIGHDRVI----------------------
>UniRef50_D2C4G5(40-311:311) Phosphoribosylformylglycinamidine cyclo-ligase n=8 Tax=Thermotogaceae RepID=D2C4G5_THENR  E=4e-25 s/c=0.43 id=20% cov=63%
---------------------------------------------------------------------------------NDLVCVGARPVAFLDYLGVERISEEH--ESFIKELVNVLDSVDVKLVGGETAEMPDVYRGDWDAVGFAVGVLEKRIPV--DKIKEGDVIVGIPSSGFHSNGWSLIRRIIKEEsikiEELPFELLKGTRIYREVIELFDlVKGIAHVTGGGVVRALKRVLGKLGAHVSL-----PKRDFVDWILKYVDFnEAVNTFNMGvGMFLIVEKQKVDEVLAR-------VDGTVVGKVSSD---------------------------
>UniRef50_A6Q9J4(4-265:273) Thiamin-monophosphate kinase n=1 Tax=Sulfurovum sp. NBC37-1 RepID=A6Q9J4_SULNB  E=1e-24 s/c=0.44 id=30% cov=30%
-----------------------------------------------------------------------IGRKAMLVNLSDAIAMNAQPKYALVTVSLPQNVSTEEIDALTQSLENTAAQFGCEIIGGDTV-----AGDKLHLSITII--SQSDDPLLRKGLEEGDLLAYTGTLGE--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A9GR51(20-284:329) Thiamine-phosphate kinase n=1 Tax=Sorangium cellulosum 'So ce 56' RepID=A9GR51_SORC5  E=3e-24 s/c=0.43 id=23% cov=30%
----------------------------------------------------------------------DLGYRATMAAASDLAAMGARPVGLLAALVLPPSVSDDELGALAGGQRAACDEIGTAVIGGNLSR-----GGEISITTTALGVA--ALPLRRDGARPGDALALAGPVG---------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A4A8V3(412-737:743) Selenide,water dikinase n=3 Tax=unclassified Gammaproteobacteria RepID=A4A8V3_9GAMM  E=5e-24 s/c=0.35 id=22% cov=67%
-----------------------------------------------------------------------MGRIAAQHALSDLYAVGAKPHSAQALVTLPfaaPALLRRDLLMVLQGALSVFDEVGCTLDGGHSMQGPELQLGFAVNGVLAAG----DAPLPKRGAQPGDTLLLSKTLG-SGALFAAHMQGLADGRHVDDALHALeqgNGAAAKIARDYQARAVTDVTGFGLAGHLLEMlgdtlaadielgklkitdgaldAMTAGVFSTLHEPnrqaivaRWAPPEDLPLLAELL-FDPQTS---GGLLMAMPPEKAAQACEALHAQA--VEAELIGT-------------------------------
>UniRef50_B0NBN5(24-286:324) Putative uncharacterized protein n=1 Tax=Clostridium scindens ATCC 35704 RepID=B0NBN5_EUBSP  E=1e-22 s/c=0.41 id=20% cov=53%
---------------------------------------------------------------------------------------------------------------------------------------------------SGIAKVPKNDPWCKGPVPAKGEIVLTKWVGMDGMLQITMEKERELRERFAPAFlnQILSYRQEIfarqeigIARACGASAICQIGDGGILAALWNLAKEASAGISVDMKQISILQETIEVCEHYRLNPYQLASAGSLLIIA--DDGEALAEALNSRQ--VKASVIGRLTDNNDKIIHNG-EEVRYIDRPAPD------
>UniRef50_A8HR64(6-310:310) Selenophosphate synthase (Fragment) n=1 Tax=Chlamydomonas reinhardtii RepID=A8HR64_CHLRE  E=8e-22 s/c=0.35 id=23% cov=79%
----QLSHggGCGCKIAPAKLQEILKGVqldFGSPDLLVGASTSDDAAVYRLSPDLALILTTDFFM--PIVDDPRDFGRVAAANAISDVYAMGGRPLLALSVLGMPvNKLPAAVISEIVAGGADVCRQAGIPLAGGCGAARAGVG--------------------CAAGLAPG---------ALSSGGRGEGGEGRGRECVVIGTMTQLNTVGTALGQDPRVHAITDVTGFGLLGHLLEVCRGSGLAARVAAGAVPVMAPALALAQrgvfpgavernwdsygaavaveqgveswrrDLLVDPQTS---GGLLLAVEPGAAEELLAAVRAAGFS-QAAAVGR-------------------------------
>UniRef50_C8W0C8(645-942:962) Phosphoribosylformylglycinamidine synthase II n=2 Tax=Clostridia RepID=C8W0C8_DESAS  E=5e-10 s/c=0.23 id=25% cov=28%
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAVPACHDISEGGLAAALAEMCFGGNVGAEISIPAGENPEYF-----------LYNETAGCFMVEIPDGmDAAELFA-------GIPYYVIGKTVE--KLSVEILYEGRELFD-----------
>UniRef50_B1Y1E5(38-351:372) Phosphoribosylformylglycinamidine cyclo-ligase n=2 Tax=Bacteria RepID=B1Y1E5_LEPCP  E=7e-21 s/c=0.33 id=19% cov=67%
--------------------------------------------------------------------------------INDLITVGATPLVVQAYWAAGGSDwfgDDQRSQALVAGWKRACEVCQVAWGGGETPALAGIVEEGrIDLAASCTGLInPKERLSVGDKLAAGDAIVLLASSGIHANGLSLARKlverlpdgylteiapGLTYGAALLAPTTLYSPVTEALFKAGITpHYCANITGHGWRKLLRHPAELS-YRIHTVPPVTPVLRFIQQQAQQDDREAYSTLNMGaGFAIFVAAEDAERTVEIARAQ--GIAAWVAGEV------------------------------
>UniRef50_B3CNQ8(278-594:1019) Phosphoribosylformylglycinamidine synthase II domain protein n=2 Tax=Wolbachia endosymbiont of Culex quinquefasciatus RepID=B3CNQ8_WOLPP  E=1e-20 s/c=0.32 id=20% cov=48%
-----------------------------------------------------------------------------------------------------------------------------------------------------IGIIPRNINNAPSHIKEpknGDKIVIIGGrvgrDGIHGATFSSEALSGNSPSTIVQigdpiTQKKLSNAVVKARDLGLYNAITDNGAGGLSSSIGEMGKDG---FEVDLSKVLLKNDGMAPWEI-----WISESQERMTLAVPEENLPAFKQIMKTHD--VEVCVIGEFNKSGKAVVKCPPG-----------------
>UniRef50_Q58209(14-280:296) Uncharacterized protein MJ0799 n=11 Tax=Methanococcales RepID=Y799_METJA  E=2e-20 s/c=0.38 id=24% cov=62%
-------------------------------------------------------------------------------TACDVVAMGAEPKFALNAI---QAKNEDEIKLAVDGLRKQSIGLNIPIIGGNTQTVEELKS---CISVAVFGeLIDENLIIKDGGAKDGDLLIMLGDPVEGDVGERIYKAKKKFDT-----------YLEILENGIKINACKDASRGGWLGNLLEMLIKAKKGAEIK--SLPYPRATRYL--------------GTYIIAVPEEEYEKVVDIALKNKC--PVVLFGRILEKPKLII----GTKEYI------------
>UniRef50_Q05U99(309-580:655) Selenide,water dikinase n=1 Tax=Synechococcus sp. RS9916 RepID=Q05U99_9SYNE  E=7e-20 s/c=0.37 id=20% cov=40%
---------------------------------------------------------------------------------------------------------VELLSQTLAGVRSALKEQGADLIGGHTMESRQPSATPSAldcqLSLSVTGETPTGaQPWSKGPIQPGDVLLLSRGLGSGVMFAAAMQGRCDpwhLDACLKQLGTSQHSRLHELFKLeaedpGCIHACTDITGFGLLGHLNEMLAAS--------------------------------------------------------------------------------------------------
>UniRef50_B1ZXJ1(460-666:1438) Phosphoribosylformylglycinamidine synthase n=12 Tax=Bacteria RepID=B1ZXJ1_OPITP  E=1e-19 s/c=0.48 id=20% cov=34%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAFIHDVGAGGLSNALPELVNDGGRGGRFDLRKIPNDEP-----GMTPLEIWCNESQERYVLAVPAGRIDTFKQLCERERC--PFAIVGEATEEKRLVLEDPHFANKPIDLPLEILLgkpPR--
>UniRef50_A5KNH2(32-318:328) Putative uncharacterized protein n=1 Tax=Ruminococcus torques ATCC 27756 RepID=A5KNH2_9FIRM  E=2e-19 s/c=0.35 id=19% cov=77%
----------------------------------------------------------------------GIGYYAVLGAAGELAARKIQAEGISVRILFPEETEEEFLADVCGEIQKGCECIKAKLTS--LSAEGTAAVQTPIVYACAGGtkvqdpgmhaleETADKKTGNRQKFVKNRELLLCGYAGLEGSLRILEAAEEELSQRFINTFLMQAKKLrdqlitpEQILEAAKGRDISvwQIGSGGILAALWEMAEEEKIGFEIAMGSISLKQETVEICEYYRLNPYQLTSAGSYLILTDE--ADQVIEVLEKA--GARAVRLG-VAKAQNARVITSKEEIRYLDRPAPDELAR--
>UniRef50_UPI00019733F3(7-195:203) hydrogenase expression/formation protein HypE n=1 Tax=Clostridium sp. M62/1 RepID=UPI00019733F3  E=6e-19 s/c=0.51 id=23% cov=51%
---------------------------------------------------------------------------------------------------------------------------------------------------------------RPGFLKPGQDLIVAGSIGLTGAAAAARAGEKALRERFSASYAerllsldkdaenfAQNRLGEAFFREAGVTEAEPAEDGGIMNSLWNLLEAYGLGCTIELRAIPILQETVEVCEVFDINPYRLSSGGCLLMAADNGF--SALNALRKR--GVEGAVIGKVEKGIARRILNG-ETETFLDRPKPDEIEKI-
>UniRef50_A5GQA4(380-674:680) Selenophosphate synthase fused with a FAD/NAD(P)-binding domain n=1 Tax=Synechococcus sp. RCC307 RepID=A5GQA4_SYNR3  E=6e-18 s/c=0.32 id=29% cov=29%
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLVE-LLAAHGCSACTDVTGFGLLGHLNEMLDASmGVDVQLQADQVPALAGSLELLEAgitstlapsnavalarwpellgtrarLLIDPQT---CGPLLAAVPEQQAGPCLAAMRLAGFS-QAVRIGTV------------------------------
>UniRef50_Q1R8H7(235-606:1295) Phosphoribosylformylglycinamidine synthase n=389 Tax=cellular organisms RepID=PUR4_ECOUT  E=4e-17 s/c=0.25 id=20% cov=53%
----------------------------------------------------------------------------------------------------------------------------------------------------GIGNIRADH-VQKGEINVGAKLVVLGGPamniglgGGAASSMASGQSDADLDfasvqrdnPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFEL-----RDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERA--PYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLL----
>UniRef50_A3MTW6(11-254:293) Thiamine monophosphate kinase-like protein n=5 Tax=Thermoproteaceae RepID=A3MTW6_PYRCJ  E=9e-17 s/c=0.37 id=21% cov=66%
-------------------EKGFLRWLLGELGVEEDDVAYVDG---------LVVKVDGAAASTsrlPFQTWADFGWRNVAAAYSDVRVKFAEARLLLASVTAP---DLGTAAEVVQGVREASQFFSLAYVGGDLNEGRDVVVDVVL-----VGWA---RARVGRAPRPGDVLVTIPQFGYTSLAYRFWQMGGAVVERGVEALKRPKPLWP--LPPAECVTAAMDSSDGLGDVLWSMAR--GVDIVVKE--LPAPREVLEFAAERGLD-----------------------------------------------------------------------
>UniRef50_A6G6A8(1-248:264) Selenide, water dikinase n=1 Tax=Plesiocystis pacifica SIR-1 RepID=A6G6A8_9DELT  E=1e-16 s/c=0.36 id=24% cov=58%
-------------------------------------------------------------------------------------------------------LPLTVLRDIMRGSSQACAEAGVAVVGGHTV---RNGDLKFGLAVTGMLEPDARRSLANTRAMPGQQLVLTKALG-TGIVASAIKKGVATPAQVdaaVRSMTRLNGEAAHAARRLGATACTDVTGFGLLGHLSNILEGSRLRAELELERLPLLPG---ALEHLGAGIYPGGSkanlshvegrlrrahastnnrafalthiaadaqtSGGLLVAMPPDGAERLVEALRS--SGHPAAIVGE-------------------------------
>UniRef50_C0DBU4(5-194:200) Putative uncharacterized protein n=2 Tax=Clostridiales RepID=C0DBU4_9CLOT  E=2e-16 s/c=0.47 id=23% cov=54%
------------------------------------------------------------------------------------------------------------------------------------------------------GQGPRGFKRRDGEMRPGQDLIMAGYAGLDGACGIARARREELERRFCSAFLKqlagspgPSPVIWAGEHLGAdITAYEVLGEGGVLAALWNLSGVFNAGIEFDLRRIPIRQATVEICELYGLNPYRLRSGGGFMAAA--DNGGRAVRALEAA--GIPAAVIGSVIPGTARRMSHGGESAGFLERPQPDEYDKIC
>UniRef50_A5ZQT1(17-187:204) Putative uncharacterized protein n=1 Tax=Ruminococcus obeum ATCC 29174 RepID=A5ZQT1_9FIRM  E=1e-13 s/c=0.47 id=27% cov=30%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGILSGLWKMAEASGVGMDVDLRRIPIRQETIEVCERLDVDPYKLEAKGSVLIGTAQGDA--LVRELEAH--GIHAAVIGYADSGND-RLLHSGEITRYLERPR--------
>UniRef50_C9PSX2(315-549:1255) Phosphoribosylformylglycinamidine synthase n=3 Tax=Prevotella RepID=C9PSX2_9BACT  E=5e-11 s/c=0.30 id=16% cov=51%
--------------------------------------------------------------------------------------------------------------------------------------------DKVIMLAGGVGYGTKRDCLKGEPQKGNKVVVVGGDnyrIGLGGGSVSSVDTGRysngielnAIQRANPEMQKRAYNLVRALVESddNPVVSIHDHGSAGHLNCLSELVEECG--GEINMDQLPIGDKTLSAKEIIANE-----SQERMGLLIDEQHIERVREIAERERA--PFYVVGETTGDAHFAFKQADGTK---------------
>UniRef50_Q21VR6(421-675:1409) Phosphoribosylformylglycinamidine synthase n=11 Tax=Bacteria RepID=Q21VR6_RHOFD  E=2e-08 s/c=0.25 id=16% cov=33%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILAIHDVGAGGLSNAFPELTNDAGRGARFDLRAVPL-----EESGMAPKEIWCNESQERYVLAIAPESLDLFTALCERERC--PFAVVGVATDARQLELLDA-GNESPVNMPMNVLL----
>UniRef50_O41976(689-968:1310) 75c n=2 Tax=Murid herpesvirus 4 RepID=O41976_MHV68   E=6e-06 s/c=0.19 id=28% cov=24%
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAHALEMLTSRTAILSMHDVSDGGLIAAILEMAMAGNKGCNIEMPSYITRP----------FDMLISETPG-MVIEVEKKSMEMVKAILK--------------------------------------------
>UniRef50_A6VPG0(3-337:337) Hydrogenase expression/formation protein HypE n=16 Tax=Gammaproteobacteria RepID=A6VPG0_ACTSZ  E=2e-85 s/c=0.95 id=67% cov=100%
-DFITMAHGNGGAAMQKLIREYFFEAFNNPILVQGEDQARIPLNELTKCGQKLAFSTDSFVIDPIFFPGGNIGKLAVCGTANDVAVSGAVPKYLSCGFILEEGLPLSELKTVIQAMAETCRKAGIQVVTGDTKVVQKGAVDKIFINTSGIGVIPDRLDWGAHRIEPGDQIIVSGTIGDHGATILNLRENLGIQSELQSDCAVLTPLIDLLRPIDGVKAVRDATRGGVNAVLHEYVQACGVGMLIEEAALPVRSEVRGICEILGLEALNFANEGKLVIVAKPEKTAEILTALHSHELGKNAAVIGTVTEDKKVRLAGIFGQTRLLDLPANEPLPRIC
>UniRef50_B0TWC9(12-341:341) Hydrogenase expression/formation protein HypE n=3 Tax=Francisella philomiragia RepID=B0TWC9_FRAP2  E=5e-74 s/c=0.85 id=47% cov=98%
---VDLAMGAGGKAMHHLIEQMIKKSFDSQYLAQAEDQAIL-----PQINGKIAMTTDSYVITPYFFRGGNIGSLAIHGTVNDLVVGGAKPLYISVGLILEEGLPLRDLKVILDSMAETAKKANVQIVTGDTKVVEKGKGDGIFINTTGVGVI-RDDFVTRDTLEDGDEIIINGTLGDHGVAVMSQRAGLDFECQIVSDATSLDSLVDAIYDnKCQIKTMRDPTRGGVGATLNEWANQYNVAIEIDEANLPISTEVQSACELLGLDPLYIANEGKVLIACKPSQTQKVLDCLRGHPLGENAQVIATVrkSEQSQVFMKTTFGGKRRVDWLSGEQLPRIC
>UniRef50_UPI0001C42969(4-334:334) hydrogenase expression/formation protein HypE n=1 Tax=Bacillus pseudofirmus OF4 RepID=UPI0001C42969  E=2e-70 s/c=0.81 id=45% cov=97%
--RISLAHGEGGELTHQLIQEVFMSAFSSKKE------IQHDSAVFPIEGKRIAVTTDSYVVQPIFFPGGNIGKLAITGTVNDLAVCCAVPKMITAGFILEEGFALSDLNKIVHSMAEEAKAANVKIVAGDTKVVEKGSADGIFINTTGIGAISEQ--VCSPAIKKGDCVVVSGTIGDHGIAILSARNQLGLLTDVQSDCASLHSLIQSLLEqVDGIRLMRDPTRGGLATSLVELCEDFQFSVELEEDLIPIRREVTGACNILGFDPLYLANEGKVVIVCDSTNKDKVIEIMQNHKYGEEAKVIGKVIsvndSNGKLYSRTQIGTTRRIHRLNGMILPRIC
>UniRef50_D1Y5N1(3-331:331) Hydrogenase expression/formation protein HypE n=1 Tax=Pyramidobacter piscolens W5455 RepID=D1Y5N1_9BACT  E=8e-63 s/c=0.74 id=41% cov=97%
---ISLGEGSGGRLTADLVASVIKNFAACDGQKGG-------CEDCTFIEGNLAVTTDGFTVSPRFFPGGDMGHLAVCGATNDLAVRGVRPQWLTLGMIIEEGLPRAELLRLVRSAARQCEALGATLAAGDTKVVPRGACEGVFFNVTALGRAVTPRPLGMNRLQPGDALILSTPPGRHGAVIAALRYGLDRGG-LESDCAALWPLLGPLLPLDGLRCMRDCTRGGLGTVLCEWAEATGLGMEIEEERLALHPSVAAICDILGFDPLYLASEGCALIACAPAETEIALARLRRHPLGRDAALIGAVTAEHAglVGLKTRLGGSRIVDMPVGEILPRIC
>UniRef50_D1VJK8(31-409:409) Hydrogenase expression/formation protein HypE n=1 Tax=Frankia sp. EuI1c RepID=D1VJK8_9ACTO  E=4e-62 s/c=0.63 id=50% cov=99%
-EHITMAHGAGGKATAALVDAVFLEAFRNPALEALDDGAHVDAG-----GARLVLTTDSYVVTPLFFPGGCIGDLAVNGTVNDLAVCGAKPLYLTCGFVLEEGFAVADLRRVVAAMAEAARTAGVTLVTGDTKVVPRGRADGCYVNTTGLGLfhpggstlddespmegvvaaddpvgpwpvgytppghrpTEPDRLdrLGMAHARPGDVVLVSGPIGDHGITIMLARGELDLEADLRSDTAPLSGLVERLLTAtsgpehgGGVRAMRDATRGGVATVLNELAMAAGVGVVIDEDAVPVREAVRGAAELLGIDPLYVACEGRLVAVVAPEAADAALAALLADPLGAGATVIGRVVDDPPglVLLNTAFGGTRIVDMLVGDPLPRIC
>UniRef50_A5EUI7(15-346:346) Hydrogenase expression/formation protein n=4 Tax=Proteobacteria RepID=A5EUI7_BRASB  E=2e-56 s/c=0.67 id=45% cov=99%
--RVSLAHGNGGRRMRQLIEELFVRHLGNALLDTDADAAALP---PLPTGATPMITTDGFTVDPLEFPGGNIGSLAVHGTVNDLAVSGAEPLYLTLNCFLEEGLDLGLLDRLTASMAAAATEAGVKVVAGDTKVVRRGEGGGVYLATSGVGLRRAGLDLGLGRIAAGDHILVSGPVGDHGTAVLLARGQFGLRGDLVSDSASVLPVTRALVDVPGLRFMRDPTRGGLATVAHEIVRHTGMGIRLSEPAIPIRDQVRAVCEMLGYNPLYLASEGRVVAVVDPASAPAALAAMRGPGQSPDAVEIGTVgCEEPYVVLETEIGGERLIEELEADPLPRIC
>UniRef50_Q57190(7-300:328) Thiamine-monophosphate kinase n=279 Tax=Gammaproteobacteria RepID=THIL_HAEIN  E=1e-53 s/c=0.72 id=26% cov=45%
----------------DLIKRYFQQQIlvdDSVQLSIGDDCALVS----VPENYQLAITTDTMVENTHFLPtisPEDLAYKAVATNLSDLAAMGAQPKWVSLALTLP-NVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGN------LSITITAQGFVEKNKGICRHKAQIGDLIYVSSTLGD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_A6W2L4(5-311:316) Thiamine-monophosphate kinase n=2 Tax=Marinomonas RepID=A6W2L4_MARMS  E=5e-50 s/c=0.65 id=23% cov=88%
----------------ELIQNIFQASVMASTQGRGDllLGIGDDCAqVQVPQGQSLVFSMDTLVEGRHFpfdADPVDIGYRAVASCVSDLAAMGAKPAFFTLGLTIPES-DPQWLAGLAQGMAELAEPIGLALVGGDTTKGP------LTITLQVHGYVEPDMAVKRSGAKLGDDIYVTGVLGDAAAAVPIVTGELQVSSERFDYFYdrywRPQPRLIVGMALKRVVHAMMDISDGLAQDIQHILKASGVGANINASRMPISAELLRWQPESAVAlALTGGDDYELCFTAPKDQAAEI--ALITQTLSLPCTKVGEIVAE-GFVIQGYDG-----------------
>UniRef50_B3PBC5(11-308:326) Thiamine-monophosphate kinase n=1 Tax=Cellvibrio japonicus Ueda107 RepID=B3PBC5_CELJU  E=2e-49 s/c=0.66 id=25% cov=85%
----------------QLIQQFFQREqaeqpAAGVVLGIGDDCALLQ----IPEGKQLAVSVDTLVSGVHFPEGAEpalIAERALRTNLSDLAAMGAEPLWFTLALTLPQA-EEQWLREFSRGLFACAKRYGIALIGGDTTAGP------LSVSIQVMGAVTPGQALRRDGANLGDFILVTHSVGDGAAALASLQGRVSFSGDdhayLHERFYRPEPRLQASARIRPFASAALDISDGLVADLQHICTASDLGAVIDVEALPLSSALVAYPDRTQayEWALSGGDDYELCFTVAPENMPDI--AMLIAQGQLQASVIGEMVAGNRVI-----------------------
>UniRef50_Q3AE31(7-315:326) Thiamine-monophosphate kinase n=1 Tax=Carboxydothermus hydrogenoformans Z-2901 RepID=Q3AE31_CARHZ  E=2e-48 s/c=0.63 id=22% cov=75%
---------------------------PGVILGIGDDAAVVEI------KGKLLVTTDLLVENVHFkrnyTKPEILGKKALAVNLSDIAAMGGIPRFCLVSLALPKTTEVNFVEGFYQGLKSMAKEYGVTLIGGDTT----GAGSEIMVAVTVLGEALEEGVLTRSGAKPGDGVYVSGYLGDSAAGLYLLLKEklgllpEEVEKYLISRHLEPEPRLELgqLLCREKFATSTNDLSDGLVKKLQEIARASGVEITINREKIPLSFALLTFCQQFTLKPldfaLHGGEDYELLFTVPAEKEEEL-------------------------------------------------
>UniRef50_A1WVF9(3-314:324) Thiamine-monophosphate kinase n=2 Tax=Ectothiorhodospiraceae RepID=A1WVF9_HALHL  E=5e-46 s/c=0.60 id=24% cov=90%
---------GGGEA--ALIQRYFHgltAQRDGVELGVGDDAALLQT-----ETGLLAACCDTLVEDIHFpgdIPPEALGHRVLAVNLSDLAAVGARPAWTLLSLTLPEK-DPQWLERFSAGFKALADRYGVALVGGDTTQGP------LSVSVTALGQVAGDHGLRRGGARPGDGVWVTGTLGDAALGLELWQEREEAtalagdPAYLAGRLFRPEPRVAAGTALLGRASAAIDVSDGLAADLSRVLDESGVGATLELEALPRSQAFIDEQGDL-RHLLHGGDDYELCFTLPAEREEEM--ACLREHAATPVTRIGTVEETPGLRGVDAGGVVCALEP----------
>UniRef50_D1BMW6(11-316:326) Thiamine-monophosphate kinase n=3 Tax=Veillonella RepID=D1BMW6_VEIPT  E=6e-46 s/c=0.61 id=19% cov=73%
----------------------------------------------------------------------DVGYRLMTANLSDVAAMGGIPRQIVLSLAVSDHIDTAILDEIYRGIKDQCMRYQLNILGGDTVRTEG----PMVWTVTIIGEIPKGTAVMRSGAKVGDVVGLTNYVGYAATGLGALSYNLVGYDMTKVGHQRPEPQIELGqkLRLLGIHSMNDISD-GLGSELNEIAVASNVSIVFEEQAIPLHEETYELAKHLQTNPvdyaLYGGEDFQLVFTAPKSLLSELEKLA-------GITLIGEVLSGpPRVQMVTLDKTIKTIE-----------
>UniRef50_C3K2R7(5-304:321) Thiamine-monophosphate kinase n=3 Tax=Gammaproteobacteria RepID=C3K2R7_PSEFS  E=6e-46 s/c=0.62 id=23% cov=85%
----------------ELIRNYFAAApcaqgGEGIALGIGDDCALL----ALPTGEQLAISTDTLVAGVHFADPCDpflLGQRSLAVAVSDLAAMGAHPLAFTLALTTPT-VDADWLQRYAQGLNAMAQRCGVGLVGGDTTRGP------LSLTLTVLGRVPAGQALTRSGARPGDLLCVGGELGNAAGALPLVLGQRSADAAiadpLLAHYWSPQPQLALGLALRGKATSAMDISDGLLADCGHIATASQVSLLIERQRLPLSTALLAFVgdDEARVAALSGGDDYVLAFTLPPAELAPLLAD------GLPIHVIGRVEPGQGVTLLDADG-----------------
>UniRef50_UPI0001C16452(32-327:349) Thiamine-monophosphate kinase n=2 Tax=Nostocaceae RepID=UPI0001C16452  E=6e-46 s/c=0.63 id=21% cov=69%
---------------------------------------------------------------------------AATANLSDLAAMGASPLGITVALGLPGDLAVNWVEQLYQGMSDCLQKYHTPIVGGDIVRSPVT-----TIGITAFGEVSPDLIIRRCTAQVGNAIVITGMHGASRAGLELLLHpqtgenlKEEEKQALIRFHQRPNPRLDVIyvlheilisglkprGDSSPVTLSGMDSSDGLADAILQICRASQVGAVLHQDKIPLVPIsNNWLTPLRWLDyALYGGEDFELVLCLPPTIAKALV-----LKLGSGAAIIGEITSGDQVILQ---------------------
>UniRef50_B4WXS9(34-321:333) Thiamine-monophosphate kinase n=1 Tax=Alcanivorax sp. DG881 RepID=B4WXS9_9GAMM  E=1e-45 s/c=0.65 id=23% cov=84%
----------------SLIRRYFHHRQGDtVVLGPGDDGALL----VPPAGQQLVMTQDTSLVDRHFpadMAPADVGYRCLAVNLSDLAAMGANPLWFLLSLTLPE-VDEDWLAEFSRGMFELADQAGISLVGGDITRGP------LAVSIQATGSVPPGLALRRDGARVGDQICLGGVTGAGLLGLEQWQAGQRHGPAI-GHFRRPRPQWELGMALRGQASACIDISDGVLADLSHILQASgGLGACLDEAALPEDPPVLAGCSADKQRAlqLQGGDDYLLLFTLPA-----------AQPVPRGCYCLGQVDAQPGIRLRQRNGA----------------
>UniRef50_Q1N2P0(5-284:305) Thiamine monophosphate kinase n=1 Tax=Bermanella marisrubri RepID=Q1N2P0_9GAMM  E=3e-45 s/c=0.66 id=22% cov=65%
--------------------------HPNVRFGIGDDCA----SILPDENHELVFSMDTLVDGVHFLqtsNSFDIGTRALCVTLSDLAAMAATPIGFTLALTIPEAHST-WLQGFSQGLAEIAQRFHCPIVGGDTTRGPHC-----VITIQVHGQVKKGKALMRSGAKPGDKVFVSGDLGDGAGALSQVLENPLDSTGLAQRYFQPLPEIEFAQAIQSYATSGMDISDGLLQDLEHICRASQVGMMIDPESIPMSAD----------------------------------------------------------------------------------
>UniRef50_Q607V1(8-310:325) Thiamine-monophosphate kinase n=1 Tax=Methylococcus capsulatus RepID=Q607V1_METCA  E=5e-45 s/c=0.60 id=20% cov=82%
----------------------------NTEIGIGDDCAVLNFTAAA----RLALTTDTLVAGIHFFsdtDPTRLGHKALAVNLSDLAAMGARPRWALLALTLPEN-DPEWIAAFAQGFFRLAERHRVQLIGGDTTRGP------LAITVHALGTVDGRPGVKRAGAKPGDAIYLTGSIGLAGLGLRIRQGAYLVpDEEALDRLEAPQPRTDFGIRLGEFASAGIDVSDGLAADLGHILEQSSVGAEVDWESLPLSAGVGRYVADSGDWqmPLVAGDDYELCFTASPAYAQA--IASAADATATPVRRIGTIRTGSGLIIR---------------------
>UniRef50_A0LIX8(1-322:340) Thiamine-monophosphate kinase n=1 Tax=Syntrophobacter fumaroxidans MPOB RepID=A0LIX8_SYNFM  E=7e-45 s/c=0.57 id=20% cov=72%
------------------------------------------------------------------------GRKIVAINVSDIAACGGRPKWALVSLALTPDTGVDFVDGLYAGMQEEIHAAGASIVGGNLS----GIRGEIVIDLSLLGTVSPECLILRNGARSGDLVLVTGTLGESRAGLELILRpelevEQEAGDRVRARHLTPGARLREgriLAATGSIHAMADVSD-GVLGDLGHICRASEVQAEIWPESLPISPECLRVAEVARCDavqwALSGGEDYELLFTADPRRVPEIRGRLEAE-TGTSCHVIGRITgKGEAVLVRSREG-----------------
>UniRef50_B3QYZ8(21-344:373) Thiamine-monophosphate kinase n=1 Tax=Chloroherpeton thalassium ATCC 35110 RepID=B3QYZ8_CHLT3  E=9e-45 s/c=0.56 id=24% cov=79%
----------------------------------GDDCAILEFS----DTEYQVVTTDLLIEQIHFDllttPMEHLGAKAISVNVSDICAMNALPTYAVVSIALSEKLSVEMVESLYKGMSNAAKEYGLAIVGGDTSA----STAGLVISVTIVGKVKKEKVARRSTAKPGDVVCVSGVLGGSHAGLKVLMRERKLmldnlkedgsvdenyrpeiadYQDAVSRHLLPKARLDIVRlfeRRGIVPTAMIDISDGLASEIKHICKESKTGAIIEENKFPIMSHARHVADEFEEEattyALYGGEDYELLFTLSPEDAEKLQET-------DDVKIIGEIKPEAyGVVM----------------------
>UniRef50_B0MTR2(8-304:310) Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM 17216 RepID=B0MTR2_9BACT  E=9e-45 s/c=0.62 id=20% cov=82%
------------------IRDMFAAIPRNGFDGIGDDCTVFPLGS----GESLVFTADLLAENIHFLRratsARELGRKSLAVNLSDVAAMGARPIATLLSLAIPHDLPEGWIEDFMEGYRDLSAQYDVGLVGGDTTASDSG----LVVNVTAIGRIADSHIKRRSDARPGDLIAVGGSLGESGAGLRDILAG-RYDTPLAQIHRNPAPQVAEGIwlgERPEVHAMMDISD-GIASDLRHILHQSGVGAEVDTECIPTPVDLETAVS--------GGEDYKLLFTVAPESANTLLSNYRL-RFGDEFHFIGRITGGN--------------------------
>UniRef50_C6X363(34-353:364) Thiamine-monophosphate kinase n=6 Tax=Bacteroidetes RepID=C6X363_FLAB3  E=2e-43 s/c=0.56 id=21% cov=83%
-----------------LIKHLTEKFgFDNPSTET---SIGDDAAVIDPQNQKVVITTDILAEGVHFnlgyVPLKHLGYKAVVVNLSDLAAMNAIPTQILVGLAVSNRFPVEALEEIYEGIALACKRYKVDLVGGDTTSSTSG----LVMGITAIGLEQSENLIKRSGAKPNDLLVVTGDLGGAYLGLQILEREHsvylanpNMQPEMEGYDYILERQLKPeartdikktLKELDIQPTSMIDVSDGLSSEILHLADQSKVGFRLYEEKIPMDSLTISTAEELNLNPvmcaMNGGEDFELLFTIAPEDFEKI-------RNHPDFSIIGHAVE----------------------------
>UniRef50_A8VUM5(19-320:332) Beta-lactamase domain protein n=1 Tax=Bacillus selenitireducens MLS10 RepID=A8VUM5_9BACI  E=3e-43 s/c=0.59 id=25% cov=54%
----------------------------------------------------------------------DIGYKALAVNISDLAAMGAVPKQYLVSLAVPKqGWPDEETRRIYAGLEEAAALYGMDLIGGDTV----STADKLVISVTVTGIVETSVRLLRANARPGDVIAVTGPLGASLAGLdLLLDQTNGVPvpemdqDQLIRSHQRPVPQVKAGRlfAELGIRAALNDISDGISREAKEIAEASGVRMVLDWKRIPKPD-----------------------------------------------------------------------------------
>UniRef50_Q214H1(21-314:338) Thiamine-monophosphate kinase n=2 Tax=Rhizobiales RepID=Q214H1_RHOPB  E=2e-40 s/c=0.57 id=24% cov=69%
-----------------LIARYFKPLANHAGAFGLSD----DCAILTSSGDDLVLTTDAIVEGVHFLpddPPESIARKALRVNLSDLAAKGASPAGFLLTLAL-RSAEESWLAPFAKALGEDAAAFGCPLLGGDTVSTPG----PLMISVTAFGRVPAGRMVRRAGARPGDHVVVSGTIGDAALGLDILKGGPaagavsgEARAALVQRYREPQPRSALAQAVRDHASAAMDVSDGLAGDLAKLCAVSAVSAAIDAAAVPLSEAARAV------------------------------------------------------------------------------
>UniRef50_C5A4H7(44-329:334) Phosphoribosylformylglycinamidine cyclo-ligase n=5 Tax=Euryarchaeota RepID=PUR5_THEGJ  E=4e-40 s/c=0.58 id=19% cov=68%
--------------------------------------------------------------------------------VNDLLCVGAEPIALVDYLAVREP-DEKIFAEIAKGLYAGAEKAGIAIVGGETAVMPDL-INGFDLAGTAIGIVEKGKVITGEEMRPDDAVIGISSSGIHSNGLTLARkllipkygldyeyEGRKLWEWLLEPTRIYVRAVLELLERVEVHGLAHITGGGLIN----LKRLTNYGFSLEMPPIEGIFKLIHENGVPLEEMFRVFNMGvGFVAIVPPEEKEEALGILNKY---YESFELGRVTKEPGIRVEN--------------------
>UniRef50_C7NRE1(5-330:340) AIR synthase related protein domain protein n=4 Tax=Halobacteriaceae RepID=C7NRE1_HALUD  E=1e-39 s/c=0.51 id=24% cov=94%
-----------GKIDTETFDSVIAPHLGADREDVtIGPQHGVDFGVLSVEESAVVVATDPISILPE-LGFERAGRVALDIVLTDVAVSGIAPTHITVSLSLPPEMTDEELGQTWRGMADHAENLGVSIVSGHTARYEGIEYSWVG-GATALGVGDPADIVRPDGANPGDAVVLATGPGAETAGLfaTLFPEALELPAKTVATAQEcvgdilGVADATTAAAAGELTAIHDTTEGGVIGGLTEMATGAGVTFDVRRDPAPVQPGVAAVCDAIGVDPWTVTSAGSLLITAPPATAESVVEALEAH--GTPAAVIGSVEECSDTSADVILDGER-VEPPESDP-----
>UniRef50_UPI000038DF5E(1-331:343) AIR synthase n=1 Tax=Ferroplasma acidarmanus fer1 RepID=UPI000038DF5E  E=2e-39 s/c=0.50 id=21% cov=86%
------------------ISRKFFEENIINKIGTLRDEVvvppknGVDVGIVKIGDKYMAVTTDPLYIDKSF-GFKKAAWFAFHILLSDLYTSGIPASYMSIDLNLPSSITDNEFKEIWDVINEECIKYNIEVVTGHTARYNGVEF-PMVGGITLMGT--GEKFITTENAGVGDRIIMTKSCALETALILSNTFpeyvrnniGEENYKSIIGKFYTMTCVGEETLAIeygisERITSMHDATEGGLLNAIYEIGIASGNGLSVDYNKIIIDSDIEKLCNLFNIDPLRSISEGTLLITVKEQYAMEFLTILQS--SGIEASLIGEILDNSKGI-----------------------
>UniRef50_Q8DIA7(54-368:761) Phosphoribosylformylglycinamidine synthase 2 n=16 Tax=Bacteria RepID=PURL_THEEB  E=2e-39 s/c=0.52 id=22% cov=85%
---------------SRLLLKQFPTQGPRVLVGPGENAGVVDLG----DGLRLAFKIESHN-HPSAIEPFQGAATGVGGILRDIFTMGARPIALLNALRFGdlkEAKTQQLVKGVVAGIAHYGNCVGVPTVGGEVYFDPCYAGNPL-VNAMALGLMETPEIVKSAASGIGNPVLYVGSTtgrdGMGGASFASAELTDesmsDRPAVQVGDPFVEKCLIEACLEAfqtGAVVAAQDMGAAGLTCSTSEMAAKGGVGIELDLDKVPVRE-----QGMVPYEFLLSESQERMLFVAAQGREAELIEIFQR--WGLQAVVVGRVIAEPLVRV----------------------
>UniRef50_A3UCC4(34-307:336) Thiamine-monophosphate kinase n=1 Tax=Oceanicaulis alexandrii HTCC2633 RepID=A3UCC4_9RHOB  E=3e-39 s/c=0.60 id=22% cov=32%
--------------------------------------------------------------------------------LSDLAAMGADPHAYLACVVWPETGREARMTGFADGLALDQAEFGVHLAGGDTTSADG----PWMISITAFGAVPTGQAVRRAGAKPGDVAILTGTIGDAGLGLLVRQGEY--------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B2UPF2(15-285:298) Thiamine-monophosphate kinase n=2 Tax=Verrucomicrobiaceae RepID=B2UPF2_AKKM8  E=3e-39 s/c=0.61 id=27% cov=62%
---------------------------SNPSLetGPGDDCAIIRGS----GNRQLLLKTDCVVEGMHFLPGTDpelIGRKALARAVSDIGAMGGTPLHALVTLFVHADRPISQVEGIYRGMGRLARQFGISIAGGESSGLP---ADGLIINVALTGEVEAGKAVLRSTARAGDLIAVTGTLGGSF---------------PTGHHLSFTPRVREggILAASGVATSMMDLSDGLGTDLPRLAAASGLGFRIHEELLPVRPGFTAA------------------------------------------------------------------------------
>UniRef50_C5S8T0(11-316:317) Selenide, water dikinase n=3 Tax=Allochromatium vinosum RepID=C5S8T0_CHRVI  E=5e-39 s/c=0.54 id=25% cov=74%
----------------------------------------------------LVTTVDAFT--PVVDDPFDYGRIAAINSLSDIYAMGARPVSALSVAGFPDtRLPLDVLAEVLRGLVAGAASVGVPVLGGHTVKNP-----EPLFGLAVTGVIHPDRILRKGAGQAGDVLVLTKPLGIGVLTTAIKNERLGAEGlrRVTELMLTANARAAEIMVEQGARAATDITGFGLLGHLLEMVTGAGVGAELRFDAVPVLDEAFELArqglfpggartnlraysERLEFDPALEEwqrllltdpqTSGGLLITFAPEQAEDALAALQTA--GVPATIIGRLV-----------------------------
>UniRef50_D2RH67(5-291:298) Thiamine-monophosphate kinase n=1 Tax=Archaeoglobus profundus DSM 5631 RepID=D2RH67_ARCPR  E=6e-39 s/c=0.57 id=24% cov=83%
----------------ELIgkaKELFRVERDDVIVGIDDDCALVDV------GTRLALTTDCLHEKTDFpkgIKPEEIGHLALAINLSDLASCGAKPLFFLYTITLSDYW-IEYFERILKGMKNLADKYGVAVVGGDTDF-----GDELHISGFAIGKAE--RFVGRDGAKVGDKICVTGLLGKAQLSLEQLMNGFSrYEIAYPDSLFKPEPRVEEGLRIAKHANSMTDISDSLAISLHQIAKRSGVGIKIYEEKIPLDHLTKFVdYEKALELFLYSGGDYELVFTSKKS----------------EYIEIGEVIEDEGVWIVRRDGRVKEVE-----------
>UniRef50_A5UM16(37-336:339) Phosphoribosylformylglycinamidine cyclo-ligase n=8 Tax=Euryarchaeota RepID=PUR5_METS3  E=8e-39 s/c=0.54 id=19% cov=70%
-------------------------------------------------------------------------------VVNDILCVGAEPIALVDYLAVEQP-DPERAEEIAEGLVTGAKESRISIIGGETASLPGIIKD-FDLAGTGIGFVDVDKIITGEDIEAGDVLIGIESNGIHSNGYSLARKALFDDagfsiddkmpncdttigeELIRPTELYVKPIVALFKEEYDIHGLAHITGGGFT-NLRRLKKGVGYDIY-DLPEAPEIFKLIYQQNVPLEEMYKVFNMGiGFVVITNENEAEKIMETLKDY---CNCQIIGKVTDDEKITVKTFEGSE---------------
>UniRef50_A0LA23(25-351:353) Phosphoribosylformylglycinamidine cyclo-ligase n=9 Tax=cellular organisms RepID=PUR5_MAGSM  E=1e-38 s/c=0.50 id=23% cov=68%
----------------------------------------------------------------------------VAMSVNDLVVQGAEPLFFLDYFAC-GKLSPETAATVVEGIATGCRAAGCALIGGETAEMPGFYTEGeYDLAGFAVGAVDKHKIIDGRHISPGDAIIGLASSGPHSNGYSLIRKlvlgqsgpgleadfnGKPLGEVLLTPTHIYVLPLLELAKTHAIHGLVHITGGGFWENIPRILpDATGALLKRSCWQQPeVFNLLQKLGNIAEDEMLRTFNCGlGMLVIVPATQADSALAQLRAA--GEQAELVGEIT-----------------------------
>UniRef50_A8MHJ6(7-346:346) Selenide, water dikinase n=30 Tax=Bacteria RepID=SELD_ALKOO   E=1e-38 s/c=0.48 id=20% cov=54%
------------------------------------------------------------------------GQIAAANSLSDVYAMGGRPLTAMNIVCFPNCLDPKILNQILKGGADKVLESGALLVGGHTVED-----DEPKYGLSITGIVHPKKVWANSTAREGDYLILTKPVGLGVlnTAIKADIATKEQYDGAVKVMSMLNKYAFEALENLDVSACTDITGFGFLGHVYEMAKGSGVSIEIFADKVPLIDGAK--------------------------------------------------------------------------------
>UniRef50_UPI00016C3B48(12-296:303) thiamine-monophosphate kinase n=1 Tax=Gemmata obscuriglobus UQM 2246 RepID=UPI00016C3B48  E=1e-38 s/c=0.57 id=22% cov=65%
-----------------------------------------------------------------------VGRKAMAANLSDIAAMAGVPTAATVSLALPNSHGADLARELFLGLRDVADAFNVPIVGGDTNSWAGS----LVVSVTALGEATVRGPVRRGGARPGDWIFVSGPLGGSILG-----HHLDFTPRVAEALQ--------LHELVELRAMCDISD-GLSADLNHICEESRCGAVLDGDAVPITDAARELSRTSGRTPLQHalgdGEDFELVFTVSPEDGTKLL----ARRPFPSLAKIGECVET---------------------------
>UniRef50_A3EU85(36-349:350) Phosphoribosylformylglycinamidine cyclo-ligase n=3 Tax=Leptospirillum RepID=A3EU85_9BACT  E=2e-38 s/c=0.52 id=21% cov=69%
---------------------------------------------------------------------------------NDIAVMGAEPLFFLDYYA-SGRLDPEVGKRIFSGIAEGCRQAGAALLGGETAEMPGVYQDaDFDLAGFVVGIADREKIVDGRKIGLGHRLYGLPSTGIHSNGFSLVRKvlieergispgdrpewspGEDWSHILTRPTRIYVPLILEMIARVEVSAMVHVTGGGLTENVPRVLPE-GFSARINpraWEKPPVFQEIQKAGKVTTREMFQVFNMGIGLVVVVPSEAGKALEGFLSEK-GETFYFLGEVIPGGREVV----------------------
>UniRef50_UPI00003C83B8(26-302:322) thiamine monophosphate kinase n=1 Tax=Ferroplasma acidarmanus fer1 RepID=UPI00003C83B8  E=2e-38 s/c=0.58 id=18% cov=69%
--------------------------------------------------------------------------------LSDIAAMAGIPSGFLISLSVSPEYDISYLEEFYRGVRHELDKFNVSIIGGDTKEGSDFTA-----AGTIIGKQVPELIRRRSEIKPGQFLMVTNSLGSSAAGYIYYMYGINRELGIRKMLDVEPRINEAIKISASGAKFMMDLSDGVYASIHQISTDFGVGFKLYGDKIPFDRDVEKAASISNFSvsdiALSFGGDYELMFTVEKNSLEEFMAAMSHE--NIEVHCIGETYNGDNVIYDGR-------------------
>UniRef50_B5YKD2(16-323:333) Thiamine-monophosphate kinase n=1 Tax=Thermodesulfovibrio yellowstonii DSM 11347 RepID=B5YKD2_THEYD  E=4e-38 s/c=0.52 id=17% cov=65%
--------------------------------------------------------------------------------VSDIYAMGGDFKGFLFSAGVPETVSDQDFKELFDGIEDALKHYGGFLIGGDLSRS-----KNIVLSGFAVGEAEK--PILRKGAQAGDLIFITSYLGLSSAGLNLLNNLSDDEKRFIKSIrnfknckeypdrllkfkgineileRHLMPIARKPDKFKHIAKAMMDISDGLLIDLHRLCEENKVGAEIYLDQLPIHPAITKIADYLNIEPmnpiLSGGEDYELLVISDRQDAKEF-----------GLIPVGRIVEEKGIYL----------------------
>UniRef50_Q2NEB6(39-347:723) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Methanobacteriaceae RepID=PURL_METST  E=4e-38 s/c=0.52 id=18% cov=68%
------------------------------------------------------------------------------GIVRDIISMGAKPVVLLDALRFghmSNQRSKYIFDYVVKGISDYGNRIGVPTVGGEIEFDDNFQYN-PMVNVVCAGLVKKDEIVYGSAPIVGDVYLLmggtTGRDGIHGVTFASEEltsnsEVEDRPAVQVADPFTKKRVMEatyELLETLDIHGVKDLGGGGLTCCLSEMADKGGNGSLIDLNKIPLREE-----NMTPYEIMLSESQERMVFAIDSSDVEKAFEICKKHDLAH--AIIGNIIDKREFIIK---------------------
>UniRef50_Q2NEB6(403-692:723) Phosphoribosylformylglycinamidine synthase 2 n=5 Tax=Methanobacteriaceae RepID=PURL_METST  E=7e-26 s/c=0.41 id=14% cov=52%
---------------------------------------------------------------------------AVLESINNAISMGARPIALVDCLNFGNPEKPEVFWQFkeaVSGMSDVAGKFNTPFISGNVSFYNETEGVTVNPSPIVgtVGVVENTKIKTMTLKDDGDVILVVGNTYPELDGSQYYKHIHNVVQGYPPKIRLEENYnvsttIEKLIPKYndNITSVHDISKGGLIIALALMSIKSKKGVNVNISNIP--------------------------------------------------------------------------------------
>UniRef50_B2A1F9(16-312:323) Selenophosphate synthase n=1 Tax=Natranaerobius thermophilus JW/NM-WN-LF RepID=B2A1F9_NATTJ  E=2e-37 s/c=0.54 id=22% cov=55%
-----------------------------------------------------------------------FGQLAASNALSDIYAMGAEPVTCMNLLGFPiDKLSSEILNEILRGGHDKIQESGAALVGGHSLED-----NEPKYGLSVTGTVSPDKVWTNSGARSGDVLILTKPLGTGivTTAIKGELAEPHHEHSVVEAMVTLNKTAKRVLEDFNVTACTDVTGFGLLGHALEVAKASSVDIELWEENIPLLPGTQEYAE----------------------------------------------------------------------------
>UniRef50_D1C434(31-341:363) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Sphaerobacter thermophilus DSM 20745 RepID=D1C434_SPHTD  E=2e-37 s/c=0.51 id=24% cov=68%
-----------------------------------------------------------------------IGVDLVNHCVNDILACGARPLFFLDYIAA-ERFPEGLIEALVRGMTDACRKAGCALIGGETAQLPGIYQPGtYDLAGFIVGSVHRDRIVDGATIRAGDLLVGLPSSGLHTNGYSLARAAFGLDPKdaaarerlaatpawadrplgelLLEPHRSYLPVVEPLLDTGVLRGMAHITGGGIAGNVGRVIPE-GLEAVIDVRSWEPPALFRGLQQAGNIDsaeMYRVFNMGvGFVLIAAPGDAQQLAAQLEG------ARIIGEV------------------------------
>UniRef50_Q9YA95(18-335:345) Putative hydrogenase expression/formation protein HypE n=1 Tax=Aeropyrum pernix RepID=Q9YA95_AERPE  E=3e-37 s/c=0.50 id=26% cov=85%
-------------------------------------SVGEDAAIVSLGPIDLVMHLDPITE-----AGALAGWLAVHVAANDIAVTGARPRWEMLAVLMPPGSSEDSLASLLGDAVRAAEEIGVEIVGGHTEAAPGVP--RPIIVAAAAGITCGGCTTPTSAARPGDLVLQVKPAAIEGTAIIATDFADmlrsrGVGEDAIAGARMLASRVSiveeaiELAEAGVVRAMHDPTEGGVLGGLVEMALASRTVIEVEEDKIIVGEATRIVASALGIDPLRLISSGTLLATVPPDKAGEARYVL--EELGVEYSFIGRVAARSGepaLRLSSRGRVKTFREPPMDEI-----
>UniRef50_B9KZE5(23-353:359) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Thermomicrobium roseum DSM 5159 RepID=B9KZE5_THERP  E=1e-36 s/c=0.47 id=23% cov=74%
----------------------------------------------------------------------GIGIDLVHHSANDLLACGAEPLFFLDYFA-TAELEETVLEALVRGMTRACGALGCALIGGETAQLPGVYTPGaYDLAGCMVGVVPVEGIIDGRRIEPGDLVLGLPSDGLHTNGYSLVRAVLGLTGNpqhdrpllaevppwsdrslgdlLLQPHRCYVPLLRTWLRDSRLHGLAHITGGGLTGNLSRIVPD-GCRIEIDASSWPVPPLFEEIrqrGSISPTEMFRVFNMGiGFAVIGTPSFIHALQQALG------EGWIVGHVVraERPRVIVRGGMLGMQIL------------
>UniRef50_B5JLX3(27-356:360) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Verrucomicrobiae bacterium DG1235 RepID=B5JLX3_9BACT  E=3e-36 s/c=0.47 id=22% cov=69%
----------------------------------------------------------------------------VNHCIDDISVIGAEPLFFLDYLGL-GKLEPKVFKQILAGISEACAGANCALIGGETAQLPDmYSKGEYDIAGVIVGIAEKKKMLSGSTIRPGDVVIGLPSSGLHTNGYTLARKvifdkakltlkdkvpgtRQSIEKALMVPHTNYAPLLQPLLAKfnvgtsskvrkgNAVFGIAHITGGGFTGNIPRILPE-KVDVEIETSTWEPLPIFKLIGEKGGIDfdeMYEVFNMGiGMTLVVDGKQADEVLAFC--HSNGCKAVKIGQAVKGSG-------------------------
>UniRef50_A9B1J1(2-320:327) Selenide, water dikinase n=4 Tax=Chloroflexi RepID=A9B1J1_HERA2   E=4e-36 s/c=0.48 id=19% cov=69%
----------GAGALSNLISSLRLPS--SPQLLVGLDVSDDAAVYQLNQQQALVQTVDFFP--PIVDDPYSFGAIAAANALSDVYAMGGKPILALAIAGFPRDLDPAIIQAIMQGGADKVAEAGAVLAGGHTIID-----NEPKYGLCVTGLIDPALITRKAQAQPGDQLYLTKALGTGVISTASKRQiadPADLAAAIESMLKLNRHAAEHIAMLGTIRSATDITGFGLLGHGLELARNSGVGLQINSRALPL-------------------------------------------------------------------------------------
>UniRef50_B5EFU7(23-335:348) Phosphoribosylformylglycinamidine cyclo-ligase n=35 Tax=cellular organisms RepID=PUR5_GEOBB  E=5e-36 s/c=0.49 id=20% cov=66%
--------------------------------------------------------------------------------VNDIIVQGAEPLFFLDYLA-TAKLDPAKAASIIKGVSEGCVQAGCALIGGETAEMPGfYTGDEYDMAGFAVGVVEREKIIDGSSITVGNRLIGLASSGLHSNGYSLARKvilehmglgiddqlpglGKTVAEELLTPTRIYVRSVMNLLRDFNVSGLAHITGGGLLENIPRVLPN-GCKAVIKKDSWDVPEIFRIMQKAGNIeenEMFRTFNCGiGMVLVVPEKESEEIM--IRLSGLNETAFVIGEV------------------------------
>UniRef50_Q18JI5(417-633:725) Phosphoribosylformylglycinamidine synthase 2 n=8 Tax=Halobacteriaceae RepID=PURL_HALWD  E=3e-13 s/c=0.36 id=15% cov=38%
------------------------------------------------------------------------------------------------------------FKDIVQGLADMCHTLSIPVVGGNVSLYNDSTSGPIPPTPTLALVGTKKTFDAPPAALTGDgtlLLVGHQSNNLGGSELLAQIGGTDKFPALPSNPTAVVDSLARVANHPSTLATHDVSTGGLAVTLAEL------------------------------------------------------------------------------------------------------
>UniRef50_Q5GT57(18-335:346) Phosphoribosylformylglycinamidine cyclo-ligase n=14 Tax=Rickettsiales RepID=Q5GT57_WOLTR  E=1e-35 s/c=0.48 id=27% cov=29%
-------------------------------------SALFDFAALskKYDHPVLVSSTDGVGTKLLIAQEVDkhdtIGIDLVAMCVNDLLAQGATPLFFLDYFA-TGALNKDVLLSVVQGITEGCKQAKITLVGGETAEMP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_B9LT08(435-737:759) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Halobacteriaceae RepID=PURL_HALLT  E=9e-12 s/c=0.24 id=16% cov=55%
------------------------------------------------------------------------------------------------------------FKGIVDGLADACADLDAPVVGGNVSLYNDSVEGPIPPTPTLAligtrkGYNAPPAALDADSAGDSELLLIgaggADGGALGGSEYLAQAGGTDRFPTLPDTeTKSLADRVASLAAVARHEstfATHDVSDGGLAVALAELVTDAAGADVTLPDRVAVFEETP----------------GRLVVqTTDPEAVAELAGEL-------PVLRLGEVTTDGALSL----------------------
>UniRef50_C9RR83(20-333:341) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Fibrobacter succinogenes subsp. succinogenes S85 RepID=C9RR83_FIBSS  E=9e-35 s/c=0.48 id=17% cov=69%
-------------------------------------------------------------------PGQDI----VNHCCDDILVQGARPLFFLDYVA-TGRLEPGVMDKLVAGMAKACRENDLVLIGGETAEMPGFYGPGDYdISGTIVGVVERENIIDGKKIKPGTIILGLPSTGLHTNGYSLARKvlfdvagykvdtmvdgmDKSIGEALATPHRSYYPSLIDLCNKKKIQGLAHITGSGYQGNIPRILPD-NVDVIIDrttWDPPMIFKLIQQAGSVEKDEMYSTFNMGmGMLIFIDPADKAEVVAHLEA--KGEKWTQIGEVV-----------------------------
>UniRef50_B8D417(400-716:731) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Desulfurococcus kamchatkensis 1221n RepID=B8D417_DESK1  E=4e-23 s/c=0.35 id=20% cov=63%
------------------------------------------------------------------------------------------------------------FENMLKGLAWISDELGLPVVGGKVSFYNEDSSGnqvKPTLAIVGIGRVENvRKAKTMEFKEPGSYIVVIGEtlPEIGGSEYLYRVHGLEVGEIPVPRPRLEYmhgSTVRMLINEDAVSSVHDVSIGGLVTSMLEMAVASGLGAEVELSLVPSR-------GIDRLDyLLFSETQARYIVEVPLNKVEKARRIL--DEMNVVYGVVGRVSSRSQVDLL--VNGKRILELDIG-------
>UniRef50_C4Z424(4-311:313) Hydrogenase expression/formation protein HypE n=1 Tax=Eubacterium eligens ATCC 27750 RepID=C4Z424_EUBE2  E=1e-34 s/c=0.48 id=21% cov=75%
------------------------------------------------------------------------GELAVYRAVNNISAACGVADCIMDTVIIDEKSREIRLKEIIKELDRQCCIAGVGIAGGHTTVSDK--VNSPVVSVMAIGHQERVQ----NKAVAGQDIVVTKHIGMSGIRTVIDCKRDEILKVYSEDIinkalgdeteLLVAKEAEIFMQESAYGAMHDVSEGGIFAALWDMAEYSGVGIEVDLRQIPVKQEIIEICELFNVNPYILDSMGCLLMTCKNGC--DIINML--HQNGIEAAVIGKITDGNNRIIHNT-EEDRYLGLPEQDEIYR--
>UniRef50_D0RPG1(45-343:344) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=alpha proteobacterium HIMB114 RepID=D0RPG1_9RICK  E=2e-34 s/c=0.50 id=16% cov=34%
--------------------------------------------------------------------------------VNDLIVQGARPLFFLDYIAI-GKVEKNKYKKLLKGIAKGCEISKCYLAGGETAEMPGiYSNNKFDMAGFSVGIVDKFKILDGKKIQKDNLILAIPSSGLHSNGFSLVRHVLKLK-----------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_D1ATX5(55-362:363) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Anaplasma centrale str. Israel RepID=D1ATX5_ANACI  E=4e-34 s/c=0.48 id=22% cov=68%
--------------------------------------------------------------------------------VNDILAQGATPLFFLDYFS-TGSLDYDTTLEVISGIAEGCRRADTALVGGETAEMPGMYPAGCYdLAGFAVGIVEKSEILPRtDQVRTGDVIIGLASSGLHSNGFSLVRKvlqdrniaydspypladGVTWAGILLEPTRIYVRPV--LQVSQMIKAAAHITGGGLVHNIPRVLPES-LAANIQLGTWKQHSIFSWLereAQIPATEMSETFNCGiGMVLIASEDAAGRVLQVL--GESGEDAYVIGSVVlrERHSVIL----------------------
>UniRef50_B1XQD0(11-317:325) Phosphoribosylformylglycinamidine synthase II related protein, AIR synthase related protein n=1 Tax=Synechococcus sp. PCC 7002 RepID=B1XQD0_SYNP2  E=7e-34 s/c=0.48 id=18% cov=64%
--------------------------------------------------------------------------------VSDIYAMGGRPLAVVDALWACGD---QQAQQIWAGMQAAAEKFQVPIVGGHTNTHSEYDA----LGVAILGRAK--RLITSFDAQVGDRLVLVANF----QGQPRPQLPYCWDAATQADPAQLqaqWDLLPLLAERGLCSAGKDVSMGGIIGTTLMLLETSNCGAILDIGAVPCPP------QLDLQQWLLSFPSYGFLLTVSPEQVSEVE--MLCEDQGLVAQAIATITPGHTLTLK---------------------
>UniRef50_A8MCK2(57-347:724) Phosphoribosylformylglycinamidine synthase 2 n=1 Tax=Caldivirga maquilingensis IC-167 RepID=PURL_CALMQ  E=1e-33 s/c=0.50 id=21% cov=71%
----------------------------------------------------------------------------VGGIVRDILTTGLRPIALLDNLHLGSLDNQRSLWlsrNIIKGISDYGNRIGVPVVGGETWFDESFNNNPIVL-VTCIGAGDFKRVIWGEG-KVGDLVLVVGnDTGRDGMLGSSFASRELSSSDDIGAVQVGNPLLEKLLidalmelgERGLVKAIKDVGGGGLATALSELAHQLGLGIEVDLTNIRLRDELK------PEEILVSESQERMIIVVDPSRLSYVEAVLRKYEVGFDL--IGKLTNDGKFT--AYYKGIKLIDLP---------
>UniRef50_Q2NE22(9-313:333) ThiL n=1 Tax=Methanosphaera stadtmanae DSM 3091 RepID=Q2NE22_METST   E=1e-33 s/c=0.48 id=19% cov=67%
---------------RKLIQRLLKKR--DETLGNIDNTILksyhDDAAIEENTSKYTVLSTDMLIQHSHFpkqMTYFQMGEKIVTVNVSDILAMNATPVSILIAMALPSTLTIDEFDEIIDGILYKCKEYGVTLIGGDL-----NQSDEIILSATTTGKINKNIKLQ-SNIQEDNLVAITGQLGMPAAAldLLSKYEIKDLSNEYEEIIKSilepnlPIKTAKFLREHPtLITSMTDITDGLAieLGHLHE--KNTNIGFEIYADKLP--------------------------------------------------------------------------------------
>UniRef50_C3PG01(26-320:332) Thiamin-monophosphate kinase n=15 Tax=Corynebacterium RepID=C3PG01_CORA7  E=1e-33 s/c=0.49 id=25% cov=78%
-----------------------------PSALNGDDAAVLYPAA---PNSRTVAATDMMVEGRHFRRDWstaaEIGQKAIVRNFADIEAMGARPTAALLAIAAPGDTPVDFVRGIAQGIAERCAVYNAELVGGDLTRSES-----LIINVTALGSLGGsGAALTLDGARAGQKLVAHGKIGYSGAGLALLqRYGRALPPELEEF----WPLVDAhcapsltpgrgvIARATGSTSMTDNSD-GLVRDVGHLAQRSGVHIDLDRGAIAPDPLLAAAGALLDIDPWewvlTGGEDHTLLATT-----------YKSAPSGF--REIGRVMRGTGVTIDGE-------------------
>UniRef50_C1QGA1(5-284:320) Thiamine-monophosphate kinase n=2 Tax=Brachyspira RepID=C1QGA1_9SPIR  E=3e-33 s/c=0.52 id=19% cov=46%
----------------KLIEKIkkLTEYKNTNNLNIGDDCAVIKD---ISQCKDILVTSDILVENIHFslkyYSFYDVGYKSAQANISDIICKGAYPKNVFISLSIPKKINDENILEWYNGFLDACKPYNIEISGGDTTSSN----DYFFISITLIGIIEKNKSILRSNAQTDDNVYVLGFVGE--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_Q0W3P5(19-308:325) Putative thiamin-monophosphate kinase n=1 Tax=uncultured methanogenic archaeon RC-I RepID=Q0W3P5_UNCMA  E=6e-33 s/c=0.49 id=19% cov=80%
------------------IVNMFDEKGTNPSFG-------EDAAIIEAGEEALLLAADGIWDRLMRADPEWSGYCAILVNVHDIAAMGGRALGMVDIFS---SSSPELSEKVLKGMKAGVEKLGVPIVGGHIHPDTPYTA----VDVAILGRVKKDSIIYSSTAKEGDDIVLGIDLDgrVHPSCDMNWDSTFLKEAAIV---RHQMESMVELGERHLLTAGKDVSNPGILGTLGMILEVSGAGAEVELDSIPKP------ASLDWDRWLKMYPGMGFIVTCRPENTARVIEVFNNHKL--NASRIGKIVPGS--------------------------
>UniRef50_Q2RSC8(57-367:370) Phosphoribosylformylglycinamidine cyclo-ligase n=30 Tax=cellular organisms RepID=PUR5_RHORT  E=6e-33 s/c=0.46 id=24% cov=69%
--------------------------------------------------------------------------------VNDLVVQGGEPLLFLDYFA-TSRLQVPVASAVVKGIAEGCLQAGCALVGGETAEMPGMYGnNDYDLAGFAVGAVERSQLLTDDRIGLGDVLLGLASSGVHSNGFSLVRRIVERSGlawdapapfapettlarALLTPTRIYVKSCLALHRAGLVHGFAHITGGGFWENIPRVLPQ-GACAHLDGLSWPFPPVFRWLMDQGGVsahEMARTFNCGiGMVVAVPADKAEAAIALLGEH--GETVHRLGTIAargEGEAVIID---------------------
>UniRef50_B3V643(46-359:734) Phosphoribosylformylglycinamidine synthase synthetase subunit n=1 Tax=uncultured marine crenarchaeote KM3-153-F8 RepID=B3V643_9ARCH  E=2e-32 s/c=0.45 id=17% cov=69%
----------------------------------------------------------------------------VGGVLRDILSIGTRPLAVLDSLRFGKldnPNNKWLLRNVVRGIADYGNCVGIPTVGGEVAFDSCFDTNCL-VDVVCVGVGKRKNLVFSEAKNPGDVLILlggkTGRDGIHGSSFASKDldnMDSDRSAVQIPDPFTKKLIIEAtldALSTGFVSGLKDLGGGGLACALSEVSDKGNTGVEVDLNRILLRE-----SNMDPSDVLISESQERMLFIVKNGHETEISNAF--AKYDLPYSIIGKVTDTRHVIVR---------------------
>UniRef50_A7GYT8(16-262:273) Thiamine-monophosphate kinase n=3 Tax=Campylobacter RepID=A7GYT8_CAMC5  E=2e-32 s/c=0.57 id=21% cov=45%
---------------------------------------------------------------------------------SDCVVMNARPKFALLGLSLPRNFTRAQITELTRGIKKACDEFGVQVIGGDTI-----GSDALNLSVSIVGEL-AGKVVRRSGAKKGDIVAHTGRLGGSLKGLRALQNG----GQLGANSRFVKPVLRErffYAAAKFINAAMDVSD-GLGTDLTKLCAASGCGV----------------------------------------------------------------------------------------------
>UniRef50_C8SBR6(36-301:311) Methanogenesis marker protein 2 n=1 Tax=Ferroglobus placidus DSM 10642 RepID=C8SBR6_FERPL  E=7e-32 s/c=0.53 id=18% cov=57%
----------------------------------------------------------------------------------------------------------EEMEEIARGIRDACEKFDVKIVGGHIHPDAKL----PSIDVSMIGVAKS--ILRSDTAETGDKIVFAADL--EGKPHPKLPYNFDSTNKSKEVLKYQFESMVEIAERKLANAAKDVSNAGILGTIAMMMEVSGKGCEIFVDRIFKPKNVSFVQWLLSYPAC------AFVVTTKKER--EVLEVFEKH--NLAAEVIGIVTDDKKVLLK---------------------
>UniRef50_C8WHQ9(5-343:351) Selenide, water dikinase n=1 Tax=Eggerthella lenta DSM 2243 RepID=C8WHQ9_EGGLE  E=1e-31 s/c=0.41 id=22% cov=69%
-----------------------------------------------------------------------FGAIAAANALSDVFAMGAKPLTALNILAFPCSLGTDVVADVLRGGADKVREAGAFVVGGHSIED-----DEPKYGLSVFGTVHPDCIVRNGGAQPGDALFYTKVLG-SGIMNSAFRAGFEDDEgmrPVIASMMELNKAGSEAMAAAHVHAATDVTGFGLAGHLHEMLDASDASAELVWDDLPLFEGVYRYSCDFcrpaktfgIIDWARAFvrqgglgdeefenrmgvlcdpqTSGGLLVAVAPDEADEFARAFEAAAGRAPA-LIGHVRDG---------------------------
>UniRef50_A0Z0V9(7-294:311) Thiamine monophosphate kinase n=1 Tax=marine gamma proteobacterium HTCC2080 RepID=A0Z0V9_9GAMM  E=2e-31 s/c=0.48 id=25% cov=41%
-----------------------------VRLGVGDDGAVL----ALPPNSELVVSSDSLVEGTHFPEltlPEYVATRAIAAAASDLAAMAADPLAMTLALTLPDS-DELWLHSFSQGLERCVQALALPLVGGDLTRGP------LSVTVTVMGSVPTGRALRRSDAEPGDRLCVTHTLGD--------------------------------------------------------------------------------------------------------------------------------------------------------------
>UniRef50_C7JIM3(29-313:323) Selenophosphate synthetase n=8 Tax=Acetobacter pasteurianus RepID=C7JIM3_ACEP3  E=4e-30 s/c=0.47 id=17% cov=60%
--------------------------------------------------------------------------------VSDIAAMGGRPVAVVDALW---SDTSEAAASILTGLHDGANTYGVPVVGGHTNMRSTHN----SLSVAILGRARH--LLTSFDAQPGEVLIAAidlrgrwhdpHPFWDASSGLCGTEGAARLRGDIE--------LLPTIAEDGLSRAAKDISMAGLLGTALMLAECSGIGMTIMLDDIPRPEDAPM------ERWLSAFPSYGYLLTARPEDAHAIMARFR--GRGITASVIGR-------------------------------
>UniRef50_C8S195(401-730:730) Pyridine nucleotide-disulfide oxidoreductase family protein n=1 Tax=Rhodobacter sp. SW2 RepID=C8S195_9RHOB  E=2e-29 s/c=0.40 id=26% cov=66%
----------------------------------------------------------------------------------DIWAMGAAPQVALAQITLPrmsPRMQAETLREIMAAASEVFRAEGADVVGGHTA-----TGAELTLGFTVTGLAK--RILAKGGARPGDALILTKPLGTGtilAAEMAGQRApGLMLGEAVVAALASMTRSLgpDAAILTPQAHAMTDVTGFGLAGHLLEMLTASNCAAEISLPAIPLLPGAEALAatgaasslapanraactarmafndtprAALLFDPQTA---GGLLAAVPADQATALLTALHAA--NVRAAIIGQATEGaPFLTIKT--------------------
>UniRef50_A1T716(18-310:320) Thiamine-monophosphate kinase n=7 Tax=Actinomycetales RepID=A1T716_MYCVP  E=4e-29 s/c=0.45 id=21% cov=60%
-------------------------------LGPGDDAAVV-----LAPDGRVVVCTDMLVENRHFRldwsSPHDVGRKAIAQNAADIEAMGGRSTAFVVAFGAPGDTDTASAVELADGMWHEAGLMGAGIVGGDVVAAP-----QWVVSVAALGDLGGRDPVRRDGAKPGDMVAVVGELGRSQAGFTLWDSGISGHDALRRRHLVPEPPYgqGEIAARGGATAMTDVSD-GLLADLGHIASASEVSI----------------------------------------------------------------------------------------------
>UniRef50_B2GKA9(24-275:345) Selenide, water dikinase n=19 Tax=Actinomycetales RepID=B2GKA9_KOCRD  E=9e-29 s/c=0.52 id=18% cov=62%
------------------------------------DDGDDAAAVLVRPDLAVVSTADFFT--PVVDSAHDWGRIAAANALSDVYAMGGTPVVAINLVGWPRElLPMELMSEVLQGGLDVAAQAGCPVIGGHSIDAP-----EPTYGMAVTGTADPQRLLRNDAARPGLPITLTKPIGVGLLNNRHKATGEVFPAAI-ETMTALNRDASRAALAAGVEAATDVTGFGLLGHLYKMCRASGVGATIDAAAVPL-------------------------------------------------------------------------------------
>UniRef50_B0SB88(428-707:748) Phosphoribosylformylglycinamidine synthase 2 n=6 Tax=Leptospira RepID=PURL_LEPBA  E=9e-20 s/c=0.36 id=17% cov=51%
--------------------------------------------------------------------------IAVCESARNVAATGAEPYGVTNNLNFGNPYIPEnyyVFSECVRGLGDACRFLGLPVTGGNVSFYNESPEGPVFPTPTigMVGVIDDVakglRTYPRTKEDVKYALVGNFQPTISASEYLYRSQGLDTGAipniSLEKEKQTMDALIE-CRKNGLLTSAKDLSLGGLLVALAKIVIAGKKGVEV--------------------------------------------------------------------------------------------
>UniRef50_Q72IH7(45-360:725) Phosphoribosylformylglycinamidine synthase 2 n=3 Tax=Bacteria RepID=PURL_THET2  E=2e-28 s/c=0.41 id=22% cov=61%
----------------------------------------------------------------------------VGGILRDIMSMGARPIALLDSLRFGPPEEARsryLLKGVVSGIAFYGNAIGVPTVGGDLYFHEGYRENPL-VNAMCLGLL-REEHLKRSRASLGRPIYYagakTGRDGIGGAAFAS-RELKEEKAEDRPAVQVGDPFLGKLLmeatleaiELDLVEGVQDMGAAGLTSSLSELAHKSGLGVELHLDLVPTREE-----GMTPEELLLSESQERMVL-VPKEGKEKALE-----------------------------------------------
>UniRef50_C7M1V9(46-340:734) Phosphoribosylformylglycinamidine synthase II n=1 Tax=Acidimicrobium ferrooxidans DSM 10331 RepID=C7M1V9_ACIFD  E=1e-27 s/c=0.43 id=22% cov=66%
----------------------------------------------------------------------------VGGILRDIFTVGARPIALLDSLWMGPQDDARsrwITDGVVGGISAYGNAVGVPTVGGELRVDACYGANPL-VNVVAVGVAPTEALVRARAEGIGNYVVLlgapTGRDGIGGVSVLAsagfdATAEQKRPSVQVGDPFEEKKLIEaclALMRAGLVTGVQDLGGAGLTCATSETAAAAGVGMDIFLDAVPRREP-----GMTPMEVLCSESQERMLAIVEPGLLDEVIATCRRFE--VTASVIGVV------------------------------
>UniRef50_B5IK14(395-654:721) Selenide,water dikinase n=1 Tax=Cyanobium sp. PCC 7001 RepID=B5IK14_9CHRO  E=2e-23 s/c=0.43 id=28% cov=52%
------------------------------------------------------------------------GRLTALHACSDLWASGARLHSALAVVTVPEaaaSLQQEVLHQTLAGIRSVLEAHGAPLLGGHTLEARDGG--GLVVTLSVNGSVERPQHWPKGPLRPGDALLLSRPLGTGvlfAAAMAAAAEPLWIDQALSQMQQSQASLVSLLRRH-GCTACTDVTGFGLLGHLGEMVAASpaGLRVELDAAAIP--------------------------------------------------------------------------------------
>UniRef50_A8A9K5(70-352:416) AIR synthase related protein domain protein n=1 Tax=Ignicoccus hospitalis KIN4/I RepID=A8A9K5_IGNH4  E=6e-22 s/c=0.38 id=22% cov=84%
--------GEGGVGSRGLGDWAVHEALTS--LSGGGDAARV---------GDLVLAVDGFHSRLSSVPLL-MGFHAVRAAVRDVMVSGGAPVASLIDVHVADDTDVAYLLDVTAGAYVAGELTGAPLVGGSTLRIGGDAVIGNRVTGGAFAVGRKVRDWSRFNASPGDELYATVGKGGGTVTAYALTHGRPELVKLTLNVDFVYD-IKRAMEVECVKGAFDWTNGGIALDAFEISRKLGVKVVLWKSVYEaVHPELLKAFEEDGIDPLRTSVDS--VVFVAERGCE------------LPFVKVGEVEAGEGVYLEGE-------------------
>UniRef50_Q8MXD3(60-411:413) Selenophosphate synthetase (Fragment) n=8 Tax=Trypanosomatidae RepID=Q8MXD3_LEIMA  E=2e-21 s/c=0.30 id=22% cov=58%
-------------------------------------------------------------------------------------------------------------REIMKGFAERARLATTTVTGGQTVMNP-----WPLIGGVAMAVVSEAEMVRPTGlLCAGDILVLTKPLGCqvavnlkqwllrpsplyeeAIAGHISPEEIEELYNMATDSMRRLNREGARLMRKHGAHGATDVTGFGILGHANNFGAAQAVgdaprSLCLVLERLPMFKTAVAASKQMNdkyrlLEGYSAETSGGLLVAFPStTAAAAFCAELTAVDGGCPSWIVGHVEDR---------------------------
>UniRef50_UPI0001C31019(46-359:370) Phosphoribosylformylglycinamidine cyclo-ligase n=1 Tax=Conexibacter woesei DSM 14684 RepID=UPI0001C31019  E=3e-17 s/c=0.29 id=18% cov=72%
---------------------------------------------------------------------------AVAAIVNDLVCVGAVPAVVNAYFATGDSgwyAQGDRMGQIVRGWERACRDAGAAWGGGESPNLPGlVSPEGIELAGSAIGVVPSGRqPILGAELAVGDEIVIVASSGLHANGASLARMladrlpqgwstplpsGRAFGDALLDPSVQYASLVAALLDQAVPVTYMSHITGHGLRKLMRADHDLTYAIDALPPVPEVLSFMVDALEMTPADAYGTLNMGaGFAVYVKPGAGAAVVAAAEAAGLSALLA--GRVEQGPRSVVLAPLG-----------------
>UniRef50_Q47XX7(288-620:1320) Phosphoribosylformylglycinamidine synthase n=64 Tax=Proteobacteria RepID=PUR4_COLP3  E=2e-15 s/c=0.26 id=16% cov=28%
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAFIHDVGAGGLSNAFPELVADGGRGGIFELRNVPNDERSMAPHEI-----WCNESQERYVIAVSDKNLATFEQICQRERA--PYSVVGRATEEEHLTV----------------------
>UniRef50_B5XJ16(407-615:1257) Phosphoribosylformylglycinamidine synthase, synthetase subunit/Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit n=70 Tax=cellular organisms RepID=B5XJ16_STRPZ  E=5e-14 s/c=0.39 id=23% cov=49%
-----------------------------------------------------------------------------------------------------------------------------------------------------VGAAPKENVV-REKPEAGDVVILlggkTGRDGVGGATGSSKVQTVEsvetAGAEVQKGNAIEERKIQRLFRDGNVtrliKKSNDFGAGGVCVAIGELADG----LEIDLDKVPL-----KYQGLNGTEIAISESQERMSVVVRPSDVDAFIAACNKE--NIDAVVVATVTEKPNLVM--TWNGETIVDL----------
>UniRef50_Q87DN2(365-578:1322) Phosphoribosylformylglycinamidine synthase n=9 Tax=Gammaproteobacteria RepID=PUR4_XYLFT  E=7e-12 s/c=0.34 id=24% cov=33%
--------------------------------------------------------------------------------------------------------------------------------------------DKPIMLAGGLGAIDR-IHIKKLRLQPGDVIIVLGGpamlIGLGGGAASSVTSGTSTEALDFASVQRDNPEMQrrcqevidhcvALGTNNPIRSFHDVGAGGLSNAIPELLHDSEVGGVIDLAKIP--------------------------------------------------------------------------------------
>UniRef50_B0TBD5(377-602:1272) Phosphoribosylformylglycinamidine (Fgam) synthase, purl component n=3 Tax=Firmicutes RepID=B0TBD5_HELMI  E=4e-10 s/c=0.30 id=18% cov=46%
-----------------------------------------------------------------------------------------------------------------------------------------------------IGAVPRQNVV-RKAPAPGDVILLvggrTGRDGCGGATGSSKEHTAESLFTCGAEVQKGNPVTERKIQRlfrhpdvsRRIKKCNDFGAGGVSVAIGELTDG----LIVNLDAIP-----KKYEGLDGTELAIAESQERMAVVVAPEDVDAFIRL--AHEENLEVTPVASVTAEKRLKM----------------------
>UniRef50_A5EXN9(347-597:1235) Phosphoribosylformylglycinamidine synthase n=1 Tax=Dichelobacter nodosus VCS1703A RepID=A5EXN9_DICNV  E=4e-09 s/c=0.26 id=20% cov=24%
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGVCVAVGEIASS----LDINLDAVPVKYQGLSATELA-----ISESQERMAIVIAAEDFAAISDL--AAKENLSACKIAQVTDSGKMIMR---------------------
