BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (336 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A6VPG0 Hydrogenase expression/formation protein HypE n=...   469   e-131
UniRef50_C6PIR8 Hydrogenase expression/formation protein HypE n=...   326   8e-88
UniRef50_C1DUF0 Hydrogenase expression/formation protein HypE n=...   314   3e-84
UniRef50_P31906 Hydrogenase expression/formation protein hypE n=...   313   6e-84
UniRef50_P40599 Hydrogenase expression/formation protein hypE n=...   304   4e-81
UniRef50_C1F4L5 Hydrogenase expression/formation protein HypE n=...   299   1e-79
UniRef50_B8D1S4 Hydrogenase expression/formation protein HypE n=...   296   6e-79
UniRef50_D1BLS0 Hydrogenase expression/formation protein HypE n=...   292   1e-77
UniRef50_D2ATM4 Hydrogenase maturation factor-like protein n=35 ...   286   1e-75
UniRef50_P31905 Hydrogenase expression/formation protein hypE n=...   284   3e-75
UniRef50_A6LXR5 Hydrogenase expression/formation protein HypE n=...   283   6e-75
UniRef50_B0TWC9 Hydrogenase expression/formation protein HypE n=...   282   1e-74
UniRef50_B2TM78 Hydrogenase expression/formation protein HypE n=...   282   1e-74
UniRef50_Q0HUQ3 Hydrogenase expression/formation protein HypE n=...   277   3e-73
UniRef50_B0TCN4 Hydrogenase expression/formation protein hype n=...   277   4e-73
UniRef50_UPI0001C42969 hydrogenase expression/formation protein ...   275   2e-72
UniRef50_Q39ZF9 Hydrogenase expression/formation protein HypE n=...   275   2e-72
UniRef50_C5ZXL6 Hydrogenase expression/formation protein HypE n=...   274   3e-72
UniRef50_B7JZ80 Hydrogenase expression/formation protein HypE n=...   273   5e-72
UniRef50_A6C222 Hydrogenase expression/formation protein HypE n=...   269   8e-71
UniRef50_C6PPZ0 Hydrogenase expression/formation protein HypE n=...   268   3e-70
UniRef50_A4YFA3 Hydrogenase expression/formation protein HypE n=...   259   7e-68
UniRef50_B2KBC5 Hydrogenase expression/formation protein HypE n=...   258   2e-67
UniRef50_B5YJH9 Hydrogenase expression/formation protein HypE n=...   257   3e-67
UniRef50_B4S328 Hydrogenase expression/formation protein HypE n=...   256   6e-67
UniRef50_A7I1Q2 Hydrogenase expression/formation protein HypE n=...   254   3e-66
UniRef50_A4CGN3 Hydrogenase expression/formation protein HypE n=...   254   3e-66
UniRef50_B7JF80 Hydrogenase expression/formation protein HypE n=...   254   3e-66
UniRef50_D1A5C3 Hydrogenase expression/formation protein HypE n=...   254   4e-66
UniRef50_C8PGA7 Hydrogenase expression/formation protein HypE n=...   253   6e-66
UniRef50_C9KK60 Hydrogenase expression/formation protein HypE n=...   250   5e-65
UniRef50_A8ZNR3 Hydrogenase expression/formation protein HypE n=...   249   1e-64
UniRef50_A4XJQ3 Hydrogenase expression/formation protein HypE n=...   248   2e-64
UniRef50_C1SLC8 Hydrogenase expression/formation protein HypE n=...   247   5e-64
UniRef50_A4TCL4 Hydrogenase expression/formation protein HypE n=...   246   8e-64
UniRef50_C9LR03 Hydrogenase expression/formation protein HypE n=...   246   1e-63
UniRef50_B2UW48 Hydrogenase expression/formation protein n=12 Ta...   245   2e-63
UniRef50_A7H7N3 Hydrogenase expression/formation protein HypE n=...   243   9e-63
UniRef50_D1VJK8 Hydrogenase expression/formation protein HypE n=...   242   1e-62
UniRef50_C3XF65 Hydrogenase expression/formation protein n=3 Tax...   239   1e-61
UniRef50_B4U670 Hydrogenase expression/formation protein HypE n=...   238   2e-61
UniRef50_Q58089 Putative hydrogenase expression/formation protei...   236   8e-61
UniRef50_B9KGD0 Hydrogenase expression/formation protein HypE n=...   233   5e-60
UniRef50_B5Y920 Hydrogenase expression/formation protein HypE n=...   233   6e-60
UniRef50_A5EUI7 Hydrogenase expression/formation protein n=4 Tax...   226   8e-58
UniRef50_C7NVH7 Hydrogenase expression/formation protein HypE n=...   225   2e-57
UniRef50_A3Z0T5 Hydrogenase expression/formation protein; HypE n...   218   2e-55
UniRef50_D2LQB8 Hydrogenase expression/formation protein HypE n=...   211   2e-53
UniRef50_D1Y5N1 Hydrogenase expression/formation protein HypE n=...   209   1e-52
UniRef50_C1TK23 Hydrogenase expression/formation protein HypE n=...   205   2e-51
UniRef50_A8A9S1 Hydrogenase expression/formation protein HypE n=...   191   2e-47
UniRef50_Q8NKU8 Membrane-bound NiFe hydrogenase n=1 Tax=Acidianu...   185   2e-45
UniRef50_C5CEU2 Hydrogenase expression/formation protein HypE n=...   185   2e-45
UniRef50_B1YBW5 Hydrogenase expression/formation protein HypE n=...   182   2e-44
UniRef50_D2RDT5 Hydrogenase expression/formation protein HypE n=...   179   1e-43
UniRef50_B8D3R7 Hydrogenase expression/formation protein HypE n=...   161   3e-38
UniRef50_A3DKG6 Hydrogenase expression/formation protein HypE n=...   157   4e-37
UniRef50_UPI0001B4B0DD hydrogenase expression/formation protein ...   153   9e-36
UniRef50_B6YVE6 HypE n=9 Tax=Thermococcaceae RepID=B6YVE6_THEON        98   5e-19
UniRef50_A1S0T2 AIR synthase related protein domain protein n=2 ...    92   4e-17
UniRef50_B9KYQ7 Hydrogenase expression/formation n=2 Tax=Thermom...    92   4e-17
UniRef50_B7R791 AIR synthase related protein, C-terminal domain ...    87   7e-16
UniRef50_UPI0001909C53 HypE protein n=1 Tax=Rhizobium etli IE477...    87   7e-16
UniRef50_A8MLK1 AIR synthase related protein domain protein n=3 ...    84   7e-15
UniRef50_B0R9W2 Hydrogenase expression/formation protein n=3 Tax...    82   2e-14
UniRef50_B8I2N9 AIR synthase related protein domain protein n=6 ...    80   7e-14
UniRef50_C7NS45 AIR synthase related protein domain protein n=1 ...    80   1e-13
UniRef50_Q2RKM3 AIR synthase related protein-like n=1 Tax=Moorel...    79   2e-13
UniRef50_D1C5Z5 AIR synthase related protein domain protein n=7 ...    79   2e-13
UniRef50_B0KA39 AIR synthase related protein domain protein n=10...    79   3e-13
UniRef50_B0R2T1 Hydrogenase expression/formation protein n=2 Tax...    77   8e-13
UniRef50_B8GHF5 AIR synthase related protein domain protein n=1 ...    76   2e-12
UniRef50_Q97BE7 Hydrogenase expression formation protein HypE n=...    75   2e-12
UniRef50_A7ALQ7 Putative uncharacterized protein n=1 Tax=Parabac...    73   1e-11
UniRef50_Q6KZH8 AIR Synthase n=1 Tax=Picrophilus torridus RepID=...    73   1e-11
UniRef50_B9LTA0 AIR synthase related protein domain protein n=4 ...    72   3e-11
UniRef50_A1HSU1 Thiamine-monophosphate kinase n=1 Tax=Thermosinu...    71   4e-11
UniRef50_D1VUU5 Hydrogenase maturation factor n=1 Tax=Peptoniphi...    70   7e-11
UniRef50_C9L525 Hydrogenase maturation factor n=1 Tax=Blautia ha...    70   9e-11
UniRef50_C0CMS4 Putative uncharacterized protein n=2 Tax=Clostri...    70   1e-10
UniRef50_C6A3P3 Hydrogenase expression/formation protein HypE n=...    70   1e-10
UniRef50_C7G8J7 Hydrogenase maturation factor n=4 Tax=Clostridia...    69   2e-10
UniRef50_D2RZQ8 AIR synthase related protein domain protein n=1 ...    66   1e-09
UniRef50_A3DLS7 AIR synthase related protein domain protein n=1 ...    66   2e-09
UniRef50_B6YUV4 HypE n=3 Tax=Thermococcus RepID=B6YUV4_THEON           66   2e-09
UniRef50_C7NRE1 AIR synthase related protein domain protein n=4 ...    65   3e-09
UniRef50_A4WH94 AIR synthase related protein domain protein n=5 ...    64   9e-09
UniRef50_A4XL04 AIR synthase related protein domain protein n=2 ...    64   1e-08
UniRef50_C3N301 AIR synthase related protein domain protein n=9 ...    63   2e-08
UniRef50_A8ZNV6 Hydrogenase expression/formation protein HypE n=...    62   2e-08
UniRef50_B5Y6B6 Hydrogenase expression/formation protein HypE n=...    62   3e-08
UniRef50_Q9YA95 Putative hydrogenase expression/formation protei...    62   3e-08
UniRef50_C7H113 Hydrogenase maturation factor n=1 Tax=Eubacteriu...    62   3e-08
UniRef50_B0TDV9 Thiamine-monophosphate kinase n=1 Tax=Heliobacte...    61   7e-08
UniRef50_A5N2W0 HypE n=8 Tax=Clostridium RepID=A5N2W0_CLOK5            60   7e-08
UniRef50_Q6AQZ8 Related to hydrogenase expression/formation prot...    60   9e-08
UniRef50_A9KBN8 Thiamine-monophosphate kinase n=5 Tax=Coxiella b...    60   1e-07
UniRef50_C9RLV8 Thiamine-monophosphate kinase n=1 Tax=Fibrobacte...    58   5e-07
UniRef50_UPI000038DF5E AIR synthase n=1 Tax=Ferroplasma acidarma...    57   1e-06
UniRef50_Q9HHP1 Hydrogenase expression/formation protein n=1 Tax...    57   1e-06
UniRef50_B8D020 AIR synthase related protein domain protein n=1 ...    56   2e-06
UniRef50_C9RAP1 Thiamine-monophosphate kinase n=1 Tax=Ammonifex ...    56   2e-06
UniRef50_B2UPF2 Thiamine-monophosphate kinase n=2 Tax=Verrucomic...    55   3e-06
UniRef50_C8WRZ3 Thiamine-monophosphate kinase n=2 Tax=Alicycloba...    55   4e-06
UniRef50_A4YFC4 AIR synthase related protein domain protein n=3 ...    55   5e-06
UniRef50_D1B5R8 AIR synthase related protein n=3 Tax=Synergistac...    55   5e-06
UniRef50_Q2RZV6 Thiamine-monophosphate kinase n=1 Tax=Salinibact...    54   5e-06
UniRef50_A8MDD6 AIR synthase related protein domain protein n=1 ...    53   1e-05
UniRef50_B3QYZ8 Thiamine-monophosphate kinase n=1 Tax=Chloroherp...    53   2e-05
UniRef50_Q3ARA0 Thiamine-monophosphate kinase n=11 Tax=Chlorobia...    52   3e-05
UniRef50_C1TRR7 Hydrogenase maturation factor n=1 Tax=Dethiosulf...    52   4e-05
UniRef50_Q0W120 Putative thiamine monophosphate kinase n=2 Tax=E...    52   4e-05
UniRef50_A0L3Z7 Thiamine-monophosphate kinase n=1 Tax=Magnetococ...    51   5e-05
UniRef50_C3N8T5 AIR synthase related protein domain protein n=11...    51   5e-05
UniRef50_UPI0001BC315E hydrogenase expression/formation protein ...    51   5e-05
UniRef50_B8D469 AIR synthase related protein domain protein n=1 ...    51   6e-05
UniRef50_Q0ABQ2 Thiamine-monophosphate kinase n=3 Tax=Gammaprote...    50   1e-04
UniRef50_Q2RJB8 Thiamine-monophosphate kinase n=1 Tax=Moorella t...    50   1e-04
UniRef50_D2M233 Thiamine-monophosphate kinase n=1 Tax=Bacillus c...    49   2e-04
UniRef50_A6W2L4 Thiamine-monophosphate kinase n=2 Tax=Marinomona...    49   2e-04
UniRef50_B7AVF9 Putative uncharacterized protein n=1 Tax=Bactero...    49   4e-04
UniRef50_A3HUE4 Hydrogenase expression/formation factor related ...    49   4e-04
UniRef50_C5A3X6 Thiamine monophosphate kinase (ThiL) n=4 Tax=The...    48   5e-04
UniRef50_Q5ZXK3 Thiamine monophosphate kinase (AIR synthase) n=6...    48   6e-04
UniRef50_B8D6Q8 AIR synthase related protein domain protein n=1 ...    47   6e-04
UniRef50_C4LAD9 Thiamine-monophosphate kinase n=1 Tax=Tolumonas ...    47   0.001
UniRef50_B7V7Q7 Thiamine monophosphate kinase n=11 Tax=Gammaprot...    47   0.001
UniRef50_A1AS86 Thiamine-monophosphate kinase n=9 Tax=Desulfurom...    46   0.002
UniRef50_D0LRS0 Selenide, water dikinase n=1 Tax=Haliangium ochr...    46   0.002
UniRef50_A8VUM5 Beta-lactamase domain protein n=1 Tax=Bacillus s...    46   0.002
UniRef50_C6VU01 Thiamine-monophosphate kinase n=25 Tax=Bacteria ...    45   0.003
UniRef50_B1CC54 Putative uncharacterized protein n=1 Tax=Anaerof...    45   0.003
UniRef50_Q0K6Z2 Thiamine monophosphate kinase n=114 Tax=Proteoba...    45   0.003
UniRef50_D2QDU8 Thiamine-monophosphate kinase n=1 Tax=Spirosoma ...    45   0.003
UniRef50_D2RH67 Thiamine-monophosphate kinase n=1 Tax=Archaeoglo...    45   0.004
UniRef50_C5BS83 Thiamine-phosphate kinase n=1 Tax=Teredinibacter...    45   0.005
UniRef50_B0G472 Putative uncharacterized protein n=1 Tax=Dorea f...    45   0.005
UniRef50_C0GR51 Thiamine-monophosphate kinase n=1 Tax=Desulfonat...    45   0.005
UniRef50_D1CF57 Thiamine-monophosphate kinase n=1 Tax=Thermobacu...    44   0.007
UniRef50_B4D453 Thiamine-monophosphate kinase n=1 Tax=Chthonioba...    44   0.007
UniRef50_C4Z424 Hydrogenase expression/formation protein HypE n=...    44   0.008
UniRef50_C6X363 Thiamine-monophosphate kinase n=6 Tax=Bacteroide...    44   0.009
UniRef50_A0M637 Thiamine-monophosphate kinase n=43 Tax=Bacteroid...    44   0.010
UniRef50_C4ZI96 Hydrogenase expression/formation protein n=1 Tax...    44   0.010
UniRef50_A1RYZ9 AIR synthase related protein domain protein n=1 ...    44   0.012
UniRef50_B4UJS8 Thiamine-monophosphate kinase n=7 Tax=Cystobacte...    43   0.013
UniRef50_B4RQH6 Thiamine monophosphate kinase n=28 Tax=Neisseria...    43   0.015
UniRef50_Q9V1N8 Probable thiamine-monophosphate kinase n=3 Tax=P...    43   0.018
UniRef50_B4WXS9 Thiamine-monophosphate kinase n=1 Tax=Alcanivora...    43   0.019
UniRef50_Q57190 Thiamine-monophosphate kinase n=279 Tax=Gammapro...    42   0.024
UniRef50_B3PBC5 Thiamine-monophosphate kinase n=1 Tax=Cellvibrio...    42   0.025
UniRef50_D2LH51 Thiamine-monophosphate kinase n=1 Tax=Rhodomicro...    42   0.025
UniRef50_B1L7H6 Thiamine-monophosphate kinase n=1 Tax=Candidatus...    42   0.025
UniRef50_D0MD26 Thiamine-monophosphate kinase n=1 Tax=Rhodotherm...    42   0.030
UniRef50_D0KYD5 Thiamine-monophosphate kinase n=1 Tax=Halothioba...    42   0.034
UniRef50_C0ZK37 Thiamin-monophosphate kinase n=1 Tax=Brevibacill...    42   0.034
UniRef50_D2MI54 Thiamine-monophosphate kinase (Fragment) n=1 Tax...    42   0.039
UniRef50_D1U5K6 Thiamine-monophosphate kinase n=1 Tax=Desulfovib...    42   0.040
UniRef50_B5FBG0 Thiamine-monophosphate kinase n=7 Tax=Vibrionace...    42   0.041
UniRef50_Q214H1 Thiamine-monophosphate kinase n=2 Tax=Rhizobiale...    42   0.041
UniRef50_Q3II30 Thiamin-monophosphate kinase n=3 Tax=Alteromonad...    42   0.043
UniRef50_B8KML1 Putative thiamine-monophosphate kinase n=1 Tax=g...    41   0.048
UniRef50_B9ZS01 Thiamine-monophosphate kinase n=1 Tax=Thioalkali...    41   0.050
UniRef50_Q65TX9 ThiL protein n=4 Tax=Pasteurellaceae RepID=Q65TX...    41   0.057
UniRef50_Q5FNA0 Thiamin-monophosphate kinase n=1 Tax=Gluconobact...    41   0.070
UniRef50_C6QHP2 Thiamine-monophosphate kinase n=1 Tax=Hyphomicro...    40   0.088

>UniRef50_A6VPG0 Hydrogenase expression/formation protein HypE n=16
           Tax=Gammaproteobacteria RepID=A6VPG0_ACTSZ
          Length = 337

 Score =  469 bits (1207), Expect = e-131,   Method: Compositional matrix adjust.
 Identities = 226/333 (67%), Positives = 268/333 (80%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I +AHG+GG AMQ+LI   F EAF NP L + EDQAR+ L +L   G +LAFSTDS+VID
Sbjct: 5   ITMAHGNGGAAMQKLIREYFFEAFNNPILVQGEDQARIPLNELTKCGQKLAFSTDSFVID 64

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+FFPGGNIGKLA+CGTANDVAVSGA+P+YLSCGFILEEGLP+  LK V+ +MAET R A
Sbjct: 65  PIFFPGGNIGKLAVCGTANDVAVSGAVPKYLSCGFILEEGLPLSELKTVIQAMAETCRKA 124

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           GI +VTGDTKVVQ+GAVDK+FINT+G+G IP  + WGA  +  GD ++VSGT+GDHGATI
Sbjct: 125 GIQVVTGDTKVVQKGAVDKIFINTSGIGVIPDRLDWGAHRIEPGDQIIVSGTIGDHGATI 184

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
           LNLRE LG+  EL SDCAVLTPLI  LR I GVKA+RDATRGGVNAV+HE+  ACG G+ 
Sbjct: 185 LNLRENLGIQSELQSDCAVLTPLIDLLRPIDGVKAVRDATRGGVNAVLHEYVQACGVGML 244

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + EAALPV+  VRG+CE+LGL+ALNFANEGKLVI  +     ++L ALHSH LGK+AA+I
Sbjct: 245 IEEAALPVRSEVRGICEILGLEALNFANEGKLVIVAKPEKTAEILTALHSHELGKNAAVI 304

Query: 304 GEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           G V E K VRLAG++G  R LDLP  EPLPRIC
Sbjct: 305 GTVTEDKKVRLAGIFGQTRLLDLPANEPLPRIC 337


>UniRef50_C6PIR8 Hydrogenase expression/formation protein HypE n=3 Tax=Bacteria
           RepID=C6PIR8_9THEO
          Length = 329

 Score =  326 bits (835), Expect = 8e-88,   Method: Compositional matrix adjust.
 Identities = 160/337 (47%), Positives = 220/337 (65%), Gaps = 9/337 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ + L+HG GG  M+ LI  +F +AF N ++   ED A L           + F+TDS+
Sbjct: 1   MDKVLLSHGGGGTMMESLIEEVFSKAFDNEYIKGMEDAALL--------FGNITFTTDSF 52

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IG+LA+CGT ND ++ GA P YL+  FI+EEG PME LK +V SMAETA
Sbjct: 53  TVKPIFFPGGDIGRLAVCGTVNDASMRGAKPLYLTSAFIIEEGYPMEDLKKIVKSMAETA 112

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             AG+ IV GDTKVV++G VD +FINT+G+G +  N+    +    GDV+LVSGT+GDHG
Sbjct: 113 EEAGVKIVAGDTKVVEKGGVDGVFINTSGIGVVYENVDVSIKNAKPGDVVLVSGTIGDHG 172

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDI-PGVKALRDATRGGVNAVVHEFAAACG 239
             I++ RE+L  D  ++SD + L  LI+ L  +   VK LRD TRGGV  V++E +   G
Sbjct: 173 MAIMSAREELQFDPPILSDVSPLNKLIEKLMTLGKAVKVLRDPTRGGVAEVLYEISKMSG 232

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GI++ E  LPVK +V+  CE++G D L+ ANEGKL+  ++R  AE+ L  + S   GKD
Sbjct: 233 VGIKIYEDKLPVKDSVKHACEMMGFDFLHLANEGKLITVIDRKYAEEALEIMKSDKYGKD 292

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGEV + K V +  +YG  R +D P  E LPRIC
Sbjct: 293 AAIIGEVNDSKLVTINTIYGTSRIVDRPIGELLPRIC 329


>UniRef50_C1DUF0 Hydrogenase expression/formation protein HypE n=10 Tax=Bacteria
           RepID=C1DUF0_SULAA
          Length = 332

 Score =  314 bits (804), Expect = 3e-84,   Method: Compositional matrix adjust.
 Identities = 167/343 (48%), Positives = 225/343 (65%), Gaps = 18/343 (5%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I LAHG GG+  Q+LI  LF + F N  L   ED A L++        ++AF+TDS+
Sbjct: 1   MKQIMLAHGGGGEETQKLIKELFFKYFNNEILLSMEDSAVLNI------NSKVAFTTDSF 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            I P+FF GG+IGKLAI GT ND++V GA P YLSC FI+EEG P E L+ +V SMAE  
Sbjct: 55  TISPIFFSGGDIGKLAIAGTVNDLSVMGAKPLYLSCSFIIEEGFPFEDLEKIVKSMAEEL 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWG--AQTLTAGDVLLVSGTLGD 178
           +  G  IVTGDTKVV RG VDK+FINT+G+G +   ++ G  A  L+ GD ++VSGT+GD
Sbjct: 115 KKTGTLIVTGDTKVVPRGFVDKIFINTSGLGKV---VYEGVSAHNLSEGDSIIVSGTVGD 171

Query: 179 HGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VKALRDATRGGVNAVVHEFA 235
           HG  I+  RE + +  +L+SDC  +  L++ L  I G   +KA+RD TRGG++AV++E+A
Sbjct: 172 HGVCIMAQREGIDMQTDLISDCDSVWTLVEDL--IKGNVKIKAMRDPTRGGLSAVLNEWA 229

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
            +    IE+ E  +PVKP V+G+CELLGL+    ANEG++V+AV +   E+ L  L  +P
Sbjct: 230 ESSNVEIEVLEEKIPVKPQVQGLCELLGLEPYVLANEGRIVVAVSKEDTEKALEILRKNP 289

Query: 296 LGKDAALIGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           LGKDA LIG+V    +K V L   YG  R ++ P  E LPRIC
Sbjct: 290 LGKDAQLIGKVNSKGKKRVILKTSYGSLRIMEPPAGEILPRIC 332


>UniRef50_P31906 Hydrogenase expression/formation protein hypE n=170 Tax=Bacteria
           RepID=HYPE_BRAJA
          Length = 346

 Score =  313 bits (801), Expect = 6e-84,   Method: Compositional matrix adjust.
 Identities = 167/337 (49%), Positives = 215/337 (63%), Gaps = 9/337 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           + L+HGSGG+AM QLI+ LF EAF N WLA   DQ+  D+        R+  +TD YV+ 
Sbjct: 15  VDLSHGSGGRAMAQLISGLFHEAFGNEWLARGNDQSAFDV-----RAGRMVMTTDGYVVS 69

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGGNIG LA+ GT ND+A++GA P YLS  FI+EEG     LK +  SM   AR A
Sbjct: 70  PLFFPGGNIGSLAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFADLKLIAESMGAAAREA 129

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            + I+TGDTKVV+RG  D LFI+TAG+G +P  +   A+    GD +L+SGTLGDHG  I
Sbjct: 130 DVHIITGDTKVVERGKADGLFISTAGVGVVPDGLDLSAEKARVGDRVLISGTLGDHGVAI 189

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDI--PGVKALRDATRGGVNAVVHEFAAACGCG 241
           ++ R+ L  + E+VSD A L  L+  +      G++ +RD TRGG+ A ++E A     G
Sbjct: 190 MSKRQNLAFETEIVSDSASLHDLVARMVQAGGRGIRLMRDPTRGGLAATLNEIAQQSNLG 249

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             L E A+PVKP V   CELLGLD L+ ANEGKLV  V   AA  VLAA+ +HPLG+DAA
Sbjct: 250 FHLLEEAIPVKPGVAAACELLGLDPLHVANEGKLVAIVAPEAAGAVLAAMRAHPLGRDAA 309

Query: 302 LIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            IGE V  +   V++A  +G  R +D    E LPRIC
Sbjct: 310 DIGEAVADDHHFVQMATSFGGGRIVDWLSGEQLPRIC 346


>UniRef50_P40599 Hydrogenase expression/formation protein hypE n=110 Tax=Bacteria
           RepID=HYPE_RHILV
          Length = 350

 Score =  304 bits (778), Expect = 4e-81,   Method: Compositional matrix adjust.
 Identities = 156/337 (46%), Positives = 215/337 (63%), Gaps = 9/337 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L+HG+GG+AM QLI  +F +AF N WL    DQ+   +      G R+  +TD YV+ 
Sbjct: 19  IDLSHGAGGRAMGQLIEGIFHKAFDNDWLRAGNDQSAFSV-----PGGRMVMTTDGYVVS 73

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGGNIG LA+ GT ND+A++GA+P YLS  FI+EEG P+  L+ +  SM   +R A
Sbjct: 74  PLFFPGGNIGTLAVHGTINDIAMAGAVPLYLSASFIIEEGFPLVDLERIADSMGAASREA 133

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G+ I+TGDTKVV+RG  D +FI+TAG+G  P  +   +     GD +++SG++GDHG  +
Sbjct: 134 GVPIITGDTKVVERGKADGVFISTAGIGMAPDGLDLRSDAARPGDAVIISGSIGDHGVAV 193

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACGCG 241
           ++ RE L  D ++VSD A L  L+  +    G  ++ +RD TRGG+ A ++E A+    G
Sbjct: 194 MSKRENLEFDTDIVSDSAALHGLVADMVAAGGAHIRLMRDPTRGGIAATLNEIASQSRVG 253

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             + E A+P+KP V   CE LGLD LN ANEGKLV  V    A+ VLAA+H+HPLG +AA
Sbjct: 254 FRIDEEAIPMKPEVAAACEFLGLDPLNVANEGKLVAVVAPEGADAVLAAIHAHPLGAEAA 313

Query: 302 LIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           LIG VV  +   V++   +G  R +D    E LPRIC
Sbjct: 314 LIGHVVADDNYFVQMVTSFGGGRIVDWLSGEQLPRIC 350


>UniRef50_C1F4L5 Hydrogenase expression/formation protein HypE n=5 Tax=Bacteria
           RepID=C1F4L5_ACIC5
          Length = 374

 Score =  299 bits (765), Expect = 1e-79,   Method: Compositional matrix adjust.
 Identities = 158/343 (46%), Positives = 217/343 (63%), Gaps = 14/343 (4%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
           NI + HGSGG+   +LI+ +F++ F NP L   +DQA L++      G RLAF+TDS+V+
Sbjct: 37  NIVMGHGSGGKLSAELIDKIFVQRFRNPILDRMDDQAVLEIG-----GMRLAFTTDSFVV 91

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LA+ GT ND+A+ GA P YLS  FILEEGLP + L  VV SM + A A
Sbjct: 92  TPLFFPGGDIGHLAVNGTVNDLAMCGARPLYLSAAFILEEGLPTQDLARVVESMRDAANA 151

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A I +VTGDTKVV RG  DK+FI T G+G +       A     GD +++SG +GDHG T
Sbjct: 152 ANIQLVTGDTKVVNRGKGDKVFITTTGIGIVDRPTEMSADRAQPGDKVILSGFIGDHGIT 211

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLR-------DIPGVKALRDATRGGVNAVVHEFA 235
           IL+ RE L  + +L SDCA L  L++ +        +I G++ +RD TRGGV  V++E A
Sbjct: 212 ILSQREHLEFESDLKSDCAPLHSLVEAMLNEAEANGNIKGIRCMRDPTRGGVATVLNEIA 271

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
                G+ L E+++PV+ +VRG CE+LGLD L  ANEGKL+  V    A+Q++  +  HP
Sbjct: 272 RKSHVGMRLHESSIPVRESVRGACEVLGLDPLYVANEGKLLAVVAPQIADQLIVRMRKHP 331

Query: 296 LGKDAALIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           LG ++ +IGE+    R  V +    G  R +D+   E +PRIC
Sbjct: 332 LGTESQIIGEITGQPRDMVLMKTSIGGTRVVDVLFGEQMPRIC 374


>UniRef50_B8D1S4 Hydrogenase expression/formation protein HypE n=3 Tax=Bacteria
           RepID=B8D1S4_HALOH
          Length = 334

 Score =  296 bits (759), Expect = 6e-79,   Method: Compositional matrix adjust.
 Identities = 145/339 (42%), Positives = 222/339 (65%), Gaps = 8/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           MN I LAHG+GG+ M+ LI++LF++   N  + +++D + +   + V        STD++
Sbjct: 1   MNTISLAHGNGGKMMEDLIDNLFLKYLNNDIINKKDDASPVPEIKGVP-----VISTDTF 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+DP+FFPGGNIGKL+ICGT ND+AV+GAIP YL+ GFILEEGLP++ L+ ++ SMAE +
Sbjct: 56  VVDPIFFPGGNIGKLSICGTVNDLAVTGAIPLYLTVGFILEEGLPIKHLEKIIISMAEVS 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           R A + IV GDTKVV+RG  DK+FINT G+G I   +    + +  GD ++++G++ +HG
Sbjct: 116 REANVKIVAGDTKVVERGKGDKIFINTTGVGMIGDKLKLSDENIKLGDKVIINGSIAEHG 175

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACG 239
             IL  R Q+     + SDC  L+ LI T L +  G+K +RD TRGG+  V++E A    
Sbjct: 176 LAILMERNQMDFSTSIKSDCCTLSDLIVTLLSETNGIKFMRDPTRGGMATVLNEIATRYN 235

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GIE+ E  +P+   ++ +C++LGLD L  ANEGK++I  +R  +E+++  +  HP G++
Sbjct: 236 VGIEIEEEKVPLGDEIKSLCKILGLDPLYLANEGKVLIIADREKSEKIVDIMRRHPYGRN 295

Query: 300 AALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +++IG +V+   + V L    G KR +     + LPRIC
Sbjct: 296 SSIIGTIVDNNDQQVYLKTRIGGKRIITKLMHDMLPRIC 334


>UniRef50_D1BLS0 Hydrogenase expression/formation protein HypE n=4
           Tax=Veillonellaceae RepID=D1BLS0_VEIPT
          Length = 335

 Score =  292 bits (748), Expect = 1e-77,   Method: Compositional matrix adjust.
 Identities = 154/340 (45%), Positives = 212/340 (62%), Gaps = 9/340 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  ++L HG+GG+   +L +   ++ F N  LA   D A     Q      R+AFSTDSY
Sbjct: 1   MERVRLVHGNGGRFSHELTDRFILKYFTNDLLAPLHDGA-----QFPVTAGRMAFSTDSY 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FFPGGNIGKLA+CGT ND+A++GAIP+YLSCG ILEEGL  E L  ++ +M+E A
Sbjct: 56  VVQPAFFPGGNIGKLAVCGTVNDLAMNGAIPQYLSCGLILEEGLAFEELDEILRTMSEMA 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +AA + IVTGDTKVV++G VDK++INTAG+G IP  I  G   + AG  +++SG +GDH 
Sbjct: 116 KAANVQIVTGDTKVVKKGEVDKIYINTAGIGMIPDGIDIGPHRVKAGLDIILSGAIGDHS 175

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKA--LRDATRGGVNAVVHEFAAAC 238
             ++  R  L L   L +DCA L  ++Q + D  G +   LRD TRGG+  V+ E A   
Sbjct: 176 IAVMGQRFGLDLSDSLTTDCAPLNKMVQAVLDKVGTQVALLRDPTRGGLGTVLKEIADQS 235

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI++ E A+P+   V+ VC +LG D L  ANEGK+V+ VE +   +VL  LHS   G 
Sbjct: 236 QVGIKVEETAIPIHEEVQSVCNILGYDPLYLANEGKVVLIVEPSITNEVLKILHSFKEGS 295

Query: 299 DAALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +A LIG+ +++    V L    G  R +DL   + +PRIC
Sbjct: 296 EAVLIGKTIDKNIGKVGLQTAIGGVRLIDLLGEDQVPRIC 335


>UniRef50_D2ATM4 Hydrogenase maturation factor-like protein n=35 Tax=Bacteria
           RepID=D2ATM4_STRRD
          Length = 446

 Score =  286 bits (731), Expect = 1e-75,   Method: Compositional matrix adjust.
 Identities = 168/340 (49%), Positives = 216/340 (63%), Gaps = 14/340 (4%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I LAHG+GG+A   LI ++F+EAF NP L   ED A +D          LAF+TDSYV
Sbjct: 116 DRITLAHGAGGKATHTLIEAVFLEAFRNPLLEPLEDGAVVD---------GLAFTTDSYV 166

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG+IG LA+ GT ND+A+ GA PRYLS  FI+EEG P+  L+ +  SMA  AR
Sbjct: 167 VTPLFFPGGDIGDLAVNGTVNDLAMCGARPRYLSAAFIVEEGFPVADLRRITASMAAAAR 226

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           AA + IVTGDTKVV+ G  D  +I T+G+G +   I   A     GDV++VSG +G+HG 
Sbjct: 227 AADVWIVTGDTKVVENGKADGCYITTSGVGTVERPIRLSAAAARPGDVVIVSGPIGEHGV 286

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VKALRDATRGGVNAVVHEFAAAC 238
           T++  R +L +  +L SD A L  L   L D  G   V+ LRDATRGGV  VV+E A A 
Sbjct: 287 TVMLARGELDIQADLTSDTAPLNTLTGRLLDACGDGQVRCLRDATRGGVATVVNEIAVAS 346

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
              + L E A+PV PAVRG CELLG+D L  A EG++V  V + +AE  LAAL SHPLG 
Sbjct: 347 KVAVVLEEDAIPVCPAVRGACELLGIDPLYVACEGRMVAVVAQRSAEAALAALRSHPLGS 406

Query: 299 DAALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           +AA+IG + +     V L   +G  R +DL   +PLPRIC
Sbjct: 407 EAAVIGRIGDDPPGLVLLKTSFGGTRIVDLLVGDPLPRIC 446


>UniRef50_P31905 Hydrogenase expression/formation protein hypE n=17 Tax=Bacteria
           RepID=HYPE_RALEH
          Length = 351

 Score =  284 bits (727), Expect = 3e-75,   Method: Compositional matrix adjust.
 Identities = 160/323 (49%), Positives = 208/323 (64%), Gaps = 7/323 (2%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLA 76
           QLI  LF+ AF N WL +  DQA    A  +  G R+  +TD++V+ PLFFPGG+IG L+
Sbjct: 33  QLIQELFVAAFDNEWLRQGNDQA----AFAMPAGARMVMATDAHVVSPLFFPGGDIGSLS 88

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           + GT NDVA++GA P YL+  FILEEG P+  LK +V SMA  AR AG+ IVTGDTKVV+
Sbjct: 89  VHGTINDVAMAGAKPLYLAASFILEEGFPLADLKRIVESMAGAAREAGVPIVTGDTKVVE 148

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGEL 196
           +G  D +FI T G+G +PA I         GD +L+SGT+G+HG  IL+ RE L  D E+
Sbjct: 149 QGKGDGVFITTTGVGVVPAGILIDGAGARPGDAILLSGTMGEHGVAILSKRESLEFDTEI 208

Query: 197 VSDCAVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAV 255
            SD A L  L+ Q L  +PGV+ LRD TRGG+   ++E ++  G G+ L EAA+PV P V
Sbjct: 209 RSDSAALHDLVAQMLAVVPGVRVLRDPTRGGLATTLNEISSQSGVGMVLDEAAIPVLPQV 268

Query: 256 RGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE--RKGVR 313
              CELLGLD L  ANEGKLV       A+ +LAA+  HPLG++A  IGEV+E  R  V+
Sbjct: 269 DAACELLGLDPLYVANEGKLVAICAAADADALLAAMRGHPLGREARRIGEVIEDGRHFVQ 328

Query: 314 LAGLYGVKRTLDLPHAEPLPRIC 336
           +   +G  R +D    E LPRIC
Sbjct: 329 MRTKFGGMRVVDWLSGEQLPRIC 351


>UniRef50_A6LXR5 Hydrogenase expression/formation protein HypE n=3 Tax=Clostridium
           RepID=A6LXR5_CLOB8
          Length = 333

 Score =  283 bits (724), Expect = 6e-75,   Method: Compositional matrix adjust.
 Identities = 148/340 (43%), Positives = 214/340 (62%), Gaps = 11/340 (3%)

Query: 1   MNN-IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDS 59
           MN  I+L HG GG+  + LI  LF + F N  L +++D A     Q      ++AF+TDS
Sbjct: 1   MNKMIKLIHGDGGKHTKILIEQLFYKYFNNNILLQEQDSATFTAVQ-----GKMAFTTDS 55

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           +V+ PLFF GGNIGKLA+CGT ND+AVSGA P YLS  FI+EEG  M++L+ +V SM +T
Sbjct: 56  FVVKPLFFSGGNIGKLAVCGTINDLAVSGAKPFYLSSSFIIEEGFSMQSLEEIVKSMGQT 115

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
               G  IVTGDTKVV++G+VD +FINT+G+G I     +  + +  GD ++V+G +G+H
Sbjct: 116 CLECGAKIVTGDTKVVEKGSVDGIFINTSGIGYIING--YEVKPIEEGDKIIVTGEIGEH 173

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAAC 238
           G TI   R  L + G+  SDCA L   I+ L++  P +K +RD TRGG++ V+HEF++ C
Sbjct: 174 GTTIAVERYNLKVKGDYKSDCAPLFHFIEELKEQFPSIKIMRDPTRGGLSTVLHEFSSLC 233

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI L E  +P+  +V+ +  LLGLD L  A EG++V+ V+   A++VL  + S   GK
Sbjct: 234 KLGIHLIEKEIPISESVKAINNLLGLDPLYMACEGRMVLVVKETEAKKVLDIIRSIDQGK 293

Query: 299 DAALIGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            A +IGE ++   + + +   +G KR +       LPRIC
Sbjct: 294 GARIIGEFIKDSNQNIFIENGFGGKRVVSPLEVSMLPRIC 333


>UniRef50_B0TWC9 Hydrogenase expression/formation protein HypE n=3 Tax=Francisella
           philomiragia RepID=B0TWC9_FRAP2
          Length = 341

 Score =  282 bits (722), Expect = 1e-74,   Method: Compositional matrix adjust.
 Identities = 155/336 (46%), Positives = 213/336 (63%), Gaps = 9/336 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           + LA G+GG+AM  LI  +  ++F + +LA+ EDQA L   Q+     ++A +TDSYVI 
Sbjct: 12  VDLAMGAGGKAMHHLIEQMIKKSFDSQYLAQAEDQAIL--PQI---NGKIAMTTDSYVIT 66

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P FF GGNIG LAI GT ND+ V GA P Y+S G ILEEGLP+  LK ++ SMAETA+ A
Sbjct: 67  PYFFRGGNIGSLAIHGTVNDLVVGGAKPLYISVGLILEEGLPLRDLKVILDSMAETAKKA 126

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            + IVTGDTKVV++G  D +FINT G+G I  +      TL  GD ++++GTLGDHG  +
Sbjct: 127 NVQIVTGDTKVVEKGKGDGIFINTTGVGVIRDDF-VTRDTLEDGDEIIINGTLGDHGVAV 185

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGI 242
           ++ R  L  + ++VSD   L  L+  + D    +K +RD TRGGV A ++E+A      I
Sbjct: 186 MSQRAGLDFECQIVSDATSLDSLVDAIYDNKCQIKTMRDPTRGGVGATLNEWANQYNVAI 245

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+ EA LP+   V+  CELLGLD L  ANEGK++IA + +  ++VL  L  HPLG++A +
Sbjct: 246 EIDEANLPISTEVQSACELLGLDPLYIANEGKVLIACKPSQTQKVLDCLRGHPLGENAQV 305

Query: 303 IGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           I  V   E+  V +   +G KR +D    E LPRIC
Sbjct: 306 IATVRKSEQSQVFMKTTFGGKRRVDWLSGEQLPRIC 341


>UniRef50_B2TM78 Hydrogenase expression/formation protein HypE n=4 Tax=Clostridium
           RepID=B2TM78_CLOBB
          Length = 337

 Score =  282 bits (722), Expect = 1e-74,   Method: Compositional matrix adjust.
 Identities = 145/342 (42%), Positives = 216/342 (63%), Gaps = 11/342 (3%)

Query: 1   MNN--IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTD 58
           MNN  I L+HGSGG    +LI+ +F   F N  L +Q D   L+  +      ++A + D
Sbjct: 1   MNNKIITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLNEIK-----GKIATTID 55

Query: 59  SYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
            +V+DP+FF GG+IGKL++CGT ND+AVSGA P Y++C FI+EEG   ++L+ +V SMA+
Sbjct: 56  GFVVDPIFFKGGDIGKLSLCGTINDLAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAK 115

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH-WGAQTLTAGDVLLVSGTLG 177
           TA+ + + IV GDTKVV++G   K++I+T G+G      +      + +GD +++SGT+G
Sbjct: 116 TAKESNVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNILNVNNIKSGDKIILSGTIG 175

Query: 178 DHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAA 236
           +HG  I+N RE L +D E+ SDCA L  L + + +    V+ +RD TRGG+   ++E + 
Sbjct: 176 EHGMCIVNKRENLNIDSEIKSDCAPLNSLCEIILNTSNNVRIMRDPTRGGIANTLNELSR 235

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
           +    + + E  +P+   VR   ELLG+  L  ANEGKL+  V+   AE VL+A+ +HPL
Sbjct: 236 SSLKSMMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPL 295

Query: 297 GKDAALIGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           GKDAA+IGEV+E  +  V + GL G  + L +   E LPRIC
Sbjct: 296 GKDAAIIGEVIEENKGAVYIKGLLGSTKVLQMSQGELLPRIC 337


>UniRef50_Q0HUQ3 Hydrogenase expression/formation protein HypE n=38 Tax=Bacteria
           RepID=Q0HUQ3_SHESR
          Length = 339

 Score =  277 bits (709), Expect = 3e-73,   Method: Compositional matrix adjust.
 Identities = 159/338 (47%), Positives = 214/338 (63%), Gaps = 14/338 (4%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           IQL+HG GG+ M +LI  LF   F NP L  +ED A+L+L    A      F+TDS+ + 
Sbjct: 11  IQLSHGGGGKEMNKLIRELFFAEFDNPILRSEEDAAKLELQGATA------FTTDSFTVS 64

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFF GG+IGKLAI GT ND+A+ GA P+YLSC  I+EEG  +  L  +V SMA+  + +
Sbjct: 65  PLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKELKQS 124

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAI-PANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           G  IV GDTKVV +G  D LFINT+G+G I   NI   A  +  GD ++VS  +G HGA 
Sbjct: 125 GARIVCGDTKVVPKGCADGLFINTSGVGRILRPNIS--AANVAPGDAIIVSRDVGCHGAA 182

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTL--RDIPGVKALRDATRGGVNAVVHEFAAACGC 240
           IL  RE L L+  L SDCA L P+++ L   +IP + A+RDATRGG++AV++E+AAA   
Sbjct: 183 ILMAREGLTLESALQSDCATLWPVVEQLIAANIP-IHAMRDATRGGLSAVLNEWAAAANV 241

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           GI ++EA++PV   V+G+CEL G +A++ ANEG  ++AV  + A   L  +      + A
Sbjct: 242 GITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQA 301

Query: 301 ALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A+IG V +     V L   +  KR LDLP  E LPRIC
Sbjct: 302 AIIGTVSDELPGKVILRTPWNTKRYLDLPQGELLPRIC 339


>UniRef50_B0TCN4 Hydrogenase expression/formation protein hype n=6 Tax=Firmicutes
           RepID=B0TCN4_HELMI
          Length = 360

 Score =  277 bits (709), Expect = 4e-73,   Method: Compositional matrix adjust.
 Identities = 161/360 (44%), Positives = 210/360 (58%), Gaps = 32/360 (8%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I LAHG GG    +L+  +F+  F +P L +  D A L L +      RLA +TD++V+ 
Sbjct: 6   ILLAHGDGGALTHRLVQEIFLRHFDHPALRDLTDAALLHLPE-----GRLAMTTDTFVVK 60

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGG+IGKLA+ GT ND+AVSGA P YL+  FILEEG P+  L+ VV S+A TAR A
Sbjct: 61  PLFFPGGDIGKLAVAGTVNDLAVSGARPLYLTAAFILEEGFPLADLEQVVASLARTAREA 120

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G+A+V GDTKVV+RG  D ++INT G G +PA    G   +  GD ++V+GT+GDHG  I
Sbjct: 121 GVAVVAGDTKVVERGCGDGVYINTTGAGVVPAGRDLGYHRIMPGDAVIVNGTIGDHGLAI 180

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTL--RDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
           L+ R  +  D  + SDCA +  L   L  R    V+ +RD TRGGV   ++E A + G  
Sbjct: 181 LSKRAGIEFDTPVESDCAPMNGLTDMLLERFAEAVRFMRDPTRGGVATTLNEVAQSTGLN 240

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           I L E ALPV+  V+G  ELLGLD L  ANEGK++I     A E++L  L  HPLG +AA
Sbjct: 241 IILEEQALPVREEVQGAAELLGLDPLYLANEGKVLIVAAPEAVEEILTTLRRHPLGLNAA 300

Query: 302 LIGEVV--------------ERKG-----------VRLAGLYGVKRTLDLPHAEPLPRIC 336
            IG V               +R G           V L    G  R +D+   +PLPRIC
Sbjct: 301 AIGRVEAGTGVGRGPGQGAGQRTGQGSGQGAGRGRVFLRTPLGGHRIVDMLAGDPLPRIC 360


>UniRef50_UPI0001C42969 hydrogenase expression/formation protein HypE n=1 Tax=Bacillus
           pseudofirmus OF4 RepID=UPI0001C42969
          Length = 334

 Score =  275 bits (703), Expect = 2e-72,   Method: Compositional matrix adjust.
 Identities = 149/342 (43%), Positives = 209/342 (61%), Gaps = 15/342 (4%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           +  I LAHG GG+   QLI  +FM AF++      + + + D A    EG R+A +TDSY
Sbjct: 2   VQRISLAHGEGGELTHQLIQEVFMSAFSS------KKEIQHDSAVFPIEGKRIAVTTDSY 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P+FFPGGNIGKLAI GT ND+AV  A+P+ ++ GFILEEG  +  L  +V SMAE A
Sbjct: 56  VVQPIFFPGGNIGKLAITGTVNDLAVCCAVPKMITAGFILEEGFALSDLNKIVHSMAEEA 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +AA + IV GDTKVV++G+ D +FINT G+GAI   +   A  +  GD ++VSGT+GDHG
Sbjct: 116 KAANVKIVAGDTKVVEKGSADGIFINTTGIGAISEQVCSPA--IKKGDCVVVSGTIGDHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACG 239
             IL+ R QLGL  ++ SDCA L  LIQ+ L  + G++ +RD TRGG+   + E      
Sbjct: 174 IAILSARNQLGLLTDVQSDCASLHSLIQSLLEQVDGIRLMRDPTRGGLATSLVELCEDFQ 233

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             +EL E  +P++  V G C +LG D L  ANEGK+VI  +    ++V+  + +H  G++
Sbjct: 234 FSVELEEDLIPIRREVTGACNILGFDPLYLANEGKVVIVCDSTNKDKVIEIMQNHKYGEE 293

Query: 300 AALIGEVVERKGVRLAGLY-----GVKRTLDLPHAEPLPRIC 336
           A +IG+V+         LY     G  R +   +   LPRIC
Sbjct: 294 AKVIGKVISVNDSN-GKLYSRTQIGTTRRIHRLNGMILPRIC 334


>UniRef50_Q39ZF9 Hydrogenase expression/formation protein HypE n=3
           Tax=Deltaproteobacteria RepID=Q39ZF9_GEOMG
          Length = 349

 Score =  275 bits (702), Expect = 2e-72,   Method: Compositional matrix adjust.
 Identities = 156/336 (46%), Positives = 205/336 (61%), Gaps = 8/336 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L HGSGG+   QL++ L +   +   LA Q D A ++       G RLAF+TDSYV+D
Sbjct: 19  ILLGHGSGGKLSHQLLDDLIIPTLSGIPLAGQNDAAVVEHG-----GQRLAFTTDSYVVD 73

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+FFPGGNIG LA+ GT ND+A+ GA P ++S G I+EEG     L  ++ SM   A AA
Sbjct: 74  PIFFPGGNIGSLAVNGTVNDLAMMGARPLFISAGLIVEEGFSRTELAGILASMRGAADAA 133

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G+ IVTGDTKVV RG  D++FINT+G+GA+  +         AGDV++++GT+GDHG  +
Sbjct: 134 GVRIVTGDTKVVPRGKADRIFINTSGIGAVEHDFAINGANARAGDVVIINGTIGDHGIAV 193

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACGCG 241
           +  RE L L   + SDCA L  L+  +    G  V  LRD TRGGV   + E A      
Sbjct: 194 MAEREGLDLRTAIRSDCAALNDLVAEIIAAGGDAVHVLRDPTRGGVATTLKEIALQSDKT 253

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           I L E  LP+  AV+GVC +LGLD L  ANEGKL+  V   AAE+VL  +  H LG+DAA
Sbjct: 254 ITLREETLPLNGAVKGVCSILGLDPLYVANEGKLLAVVAPEAAERVLTRIKGHRLGRDAA 313

Query: 302 LIGEVVERKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG V E  G V++    G  R +++   E LPRIC
Sbjct: 314 IIGHVAEGGGRVQMETAVGGMRAVEMLAGEQLPRIC 349


>UniRef50_C5ZXL6 Hydrogenase expression/formation protein HypE n=4 Tax=Helicobacter
           RepID=C5ZXL6_9HELI
          Length = 340

 Score =  274 bits (700), Expect = 3e-72,   Method: Compositional matrix adjust.
 Identities = 146/337 (43%), Positives = 210/337 (62%), Gaps = 6/337 (1%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L+HGSGG   Q+LI+ LF        +   ED    +L   +++G + A STD Y I 
Sbjct: 6   ITLSHGSGGVESQKLISELFYPFLEGCVIGNGEDAGIGELDS-ISQG-KFAISTDGYTIS 63

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGG+IGKL+ICG+ NDVA+ GA P+YLS  F++EEG  ++ LK ++ S  +T +A+
Sbjct: 64  PLFFPGGDIGKLSICGSCNDVAMMGAKPKYLSASFMIEEGFLIDDLKKILDSFGKTLKAS 123

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGA-IPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           G  +++GDTKV+ +G +DK+FI T   G  +  ++   A  +     +LVSG +G+HGA 
Sbjct: 124 GAKLLSGDTKVLPKGTLDKIFITTTAFGEFLYPHLQISAFNIPQDCCILVSGEIGNHGAV 183

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
           + + RE++ L   L SDC +L P ++ L ++   + ALRDATRGG+ +V++E+A A   G
Sbjct: 184 VYSKREEISLQSNLESDCQLLYPSLEELFKNNLSIYALRDATRGGIASVLNEWANASHIG 243

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IE+ E  LP+K  VRG+CELLG +A N ANEG  V+A+ +  +++ L  L   P GK+A 
Sbjct: 244 IEIEEETLPIKDEVRGICELLGFEAWNLANEGMCVLAIAKEDSKKALEILKRTPAGKNAT 303

Query: 302 LIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG         V L   YG KR LD P  E LPRIC
Sbjct: 304 IIGYTTSTNLNKVVLKTAYGAKRFLDYPSGELLPRIC 340


>UniRef50_B7JZ80 Hydrogenase expression/formation protein HypE n=17 Tax=Bacteria
           RepID=B7JZ80_CYAP8
          Length = 348

 Score =  273 bits (699), Expect = 5e-72,   Method: Compositional matrix adjust.
 Identities = 157/340 (46%), Positives = 208/340 (61%), Gaps = 14/340 (4%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG GG+ MQQL+  +F  AF         D A L L       +++AF+TDSYVI
Sbjct: 17  QVLLAHGGGGKLMQQLLEKMFFPAFKTTHNIPPHDSAVLSL-----NTNKIAFTTDSYVI 71

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LAI GT ND+A+SGA P YLS GFILEEGLPMETL  VV S+ + A+ 
Sbjct: 72  HPLFFPGGDIGSLAINGTVNDLAMSGARPLYLSVGFILEEGLPMETLWRVVQSLQKAAQI 131

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A + I+TGDTKVV  G  D +FINTAG+G +  N     Q++  GD +L+SG LG HG  
Sbjct: 132 AEVQIITGDTKVVDHGKGDGIFINTAGVGIVEHNQVIAPQSVQPGDAILISGDLGRHGIA 191

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVK--ALRDATRGGVNAVVHEFAAACGC 240
           I+ +RE L  +  + SDCA L+ L+  + D  GV+   LRD TRGG+ + ++E A   G 
Sbjct: 192 IMAVREGLEFETAIESDCAPLSTLVLEMLD-AGVEIHCLRDLTRGGLASALNEIATGAGV 250

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
            +++ E A+PV   V+G CE+LG D L  ANEG+LV  + +N+  + L  L SH   + A
Sbjct: 251 TLKVQETAIPVAEDVQGACEILGFDPLYVANEGRLVAFIPQNSVSRALEILRSH--HQQA 308

Query: 301 ALIGEVVERKG----VRLAGLYGVKRTLDLPHAEPLPRIC 336
           ++IG+V         V L    G  R LD+   E LPRIC
Sbjct: 309 SIIGQVTGTGTGMGLVTLESRIGASRILDMLSGEQLPRIC 348


>UniRef50_A6C222 Hydrogenase expression/formation protein HypE n=1 Tax=Planctomyces
           maris DSM 8797 RepID=A6C222_9PLAN
          Length = 358

 Score =  269 bits (688), Expect = 8e-71,   Method: Compositional matrix adjust.
 Identities = 161/341 (47%), Positives = 207/341 (60%), Gaps = 17/341 (4%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           + LAHG GG+  ++LI         N +L   +D ARL           LAF+TDS+V+ 
Sbjct: 27  VTLAHGEGGRLSRKLIQERIASVLKNEFLETSDDAARLPRVD-----GPLAFTTDSFVVS 81

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGG+IG LAI GT ND+AVSGA P +L+   ILEEG P+  L  V+ S+AE A + 
Sbjct: 82  PLFFPGGDIGSLAIYGTVNDLAVSGAHPLWLTLSLILEEGFPLMLLDRVLQSLAEAASST 141

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            + IV GDTKVV RGAVD LFINTAG+G +   +  G   L  GD L+VSG +G HG  +
Sbjct: 142 AVKIVAGDTKVVPRGAVDGLFINTAGVGKLTEPVPPGPAFLREGDELVVSGPIGQHGIAV 201

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACGCG 241
           L  REQL LD    SDC  L   ++ LR+  G  +  LRDATRGGV AV+ E+A + G  
Sbjct: 202 LAAREQLQLDPLPHSDCGSLLTAVEQLREALGDRICCLRDATRGGVAAVLQEWAGSSGLT 261

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           + + E  +PV P V+G+ ELLGLD L+ ANEG ++IAV + A ++ ++ L S     DA 
Sbjct: 262 LSIDERCVPVTPGVKGMSELLGLDPLHIANEGTMLIAVRQGAGQEAVSVLQSLSKTADAR 321

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDL------PHAEPLPRIC 336
           LIG V   KG  +A +  VKRTL L      P   PLPRIC
Sbjct: 322 LIGSV---KGRGVAAVT-VKRTLGLEQPLHDPLGSPLPRIC 358


>UniRef50_C6PPZ0 Hydrogenase expression/formation protein HypE n=6 Tax=Clostridiales
           RepID=C6PPZ0_9CLOT
          Length = 334

 Score =  268 bits (684), Expect = 3e-70,   Method: Compositional matrix adjust.
 Identities = 143/336 (42%), Positives = 202/336 (60%), Gaps = 9/336 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           + LAHG+GG+   +LI+ +F   F+NP L         D A L  +G +LAF+TD +++ 
Sbjct: 5   VTLAHGAGGRQTSELIDQVFKAHFSNPDLTAD------DAAVLNVKGGKLAFTTDGFIVS 58

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P  FPGGNIGKL+ICGT ND++  GA P YLSC F++EEG PME L+ +  +M +TA  A
Sbjct: 59  PSEFPGGNIGKLSICGTVNDLSCMGAKPLYLSCAFVIEEGFPMEKLEKIAAAMEKTADEA 118

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G+ IV GDTKV  +G VD +FI T G+G I   ++        GD ++V+G +G HG T+
Sbjct: 119 GVKIVAGDTKVAGKGQVDGVFITTTGIGQIIDGVNTSGFNAKPGDAIIVTGDIGRHGCTV 178

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           L  R + G++ ++VSDCA L   ++ + D    +  +RDATRGGV  V++E A     GI
Sbjct: 179 LLARNEFGIEADVVSDCAPLWGTVKAMLDESKDIHVIRDATRGGVGTVLYEIAEQSKVGI 238

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            L   ++PV   V+GVC +LGL+ L  A EG+LVI   +  A +++  LH     KDAA+
Sbjct: 239 RLDSKSIPVADGVKGVCGMLGLEPLYLACEGRLVIFAPKEVAPKLVDTLHEGKYSKDAAI 298

Query: 303 IGEVVERKGVR--LAGLYGVKRTLDLPHAEPLPRIC 336
           IGEV +    R  +    G +  L  P  E LPRIC
Sbjct: 299 IGEVTQDMAGRVIVKTEIGAETLLPPPGGELLPRIC 334


>UniRef50_A4YFA3 Hydrogenase expression/formation protein HypE n=1
           Tax=Metallosphaera sedula DSM 5348 RepID=A4YFA3_METS5
          Length = 352

 Score =  259 bits (663), Expect = 7e-68,   Method: Compositional matrix adjust.
 Identities = 143/354 (40%), Positives = 209/354 (59%), Gaps = 28/354 (7%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFM---EAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTD 58
           N I L HG+GG  M  LI  +F+   + F    L   +D A       V  G  + F+TD
Sbjct: 8   NVITLLHGAGGTYMHSLIRDVFLKLNDGFGEVGLEMMDDAA-------VVNG--IVFTTD 58

Query: 59  SYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
           S+VI P+FF GG+IG+L++ GT ND+A+ G  P+ LS G +LEEG P + L+ +V S+ +
Sbjct: 59  SFVIRPIFFRGGDIGRLSVSGTVNDIAMMGGDPQALSLGVVLEEGFPKDMLEKIVESIKK 118

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTA------------ 166
           TA  A + +VTGDTKV++RG +DK+ INTAG+G  P  +    +TL              
Sbjct: 119 TAEEANVHVVTGDTKVMERGNLDKIVINTAGIGTRPRQLDHNIETLRKSRQPSRWLVPTN 178

Query: 167 ---GDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDAT 223
              GD ++V+GTLGDH   +L+ RE +G +  ++SD A L  +I  L ++ G+   +D T
Sbjct: 179 LRDGDKIVVTGTLGDHAIAVLSSREGVGFESNVMSDVAPLNKMIMNLLEVGGIADAKDPT 238

Query: 224 RGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNA 283
           RGG+  ++ +++   G GI + E+ +PVK  VR   E LG+D L   NEGK V+AV    
Sbjct: 239 RGGLADLLQDWSEKSGLGIFIRESDIPVKDEVRAAVEFLGMDVLELGNEGKAVLAVSPEY 298

Query: 284 AEQVLAALHSHPLGKDAALIGEVVER-KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            + V+ ALHS PLGKDA +IGEV +  +GV +  + G  R +  P  +P+PRIC
Sbjct: 299 VKDVMDALHSDPLGKDATIIGEVRKDLEGVIMETVVGGNRYVGRPLGDPVPRIC 352


>UniRef50_B2KBC5 Hydrogenase expression/formation protein HypE n=1
           Tax=Elusimicrobium minutum Pei191 RepID=B2KBC5_ELUMP
          Length = 335

 Score =  258 bits (659), Expect = 2e-67,   Method: Compositional matrix adjust.
 Identities = 142/339 (41%), Positives = 203/339 (59%), Gaps = 10/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           N I LAHG+G +  +  I    ++ F +  LAE  D A++ +         + F+TDSYV
Sbjct: 3   NKITLAHGAGAEVSRGFIKKTLLKYFKSKSLAELSDSAKIKI-----NSKDILFTTDSYV 57

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           ++P+FFPGGNIG LA+CGT ND++VSG   +Y+S G I+EEGL ++ L+ ++ ++A  A+
Sbjct: 58  VNPVFFPGGNIGDLAVCGTVNDISVSGGDIKYISLGLIIEEGLDLKELEQILKAVALRAK 117

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            AG+ IVTGDTKVV+RG  DK+FINT+G+G   A+    A+ +  GD ++VSG L +HG 
Sbjct: 118 EAGVEIVTGDTKVVERGGADKIFINTSGIGQAIADATVKARNIKKGDKIIVSGNLAEHGI 177

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHEFAAACG 239
           +++N R +LGL G L SD A L  + +   L+    +   RD TRGG+   + E A    
Sbjct: 178 SVMNERHKLGLKG-LKSDVAPLNKITKALFLKFDKDIHMTRDLTRGGLAGALKEIAEQAK 236

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             IEL E+ +P+  AV+G   +LG+D L  ANEGK V   +   AE VL  L +   GKD
Sbjct: 237 KDIELEESRVPLSKAVKGAVSILGVDPLQTANEGKFVCIADAKKAESVLKLLKTFAYGKD 296

Query: 300 AALIGEVVE-RKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
           A + G V++ RKG V +    G  R L       LPRIC
Sbjct: 297 AKICGTVLKTRKGRVYIKTPLGASRALAEHEGSNLPRIC 335


>UniRef50_B5YJH9 Hydrogenase expression/formation protein HypE n=1
           Tax=Thermodesulfovibrio yellowstonii DSM 11347
           RepID=B5YJH9_THEYD
          Length = 332

 Score =  257 bits (657), Expect = 3e-67,   Method: Compositional matrix adjust.
 Identities = 144/339 (42%), Positives = 207/339 (61%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ I L HGSGG+ M +LI       F  P L    D A + L        ++A +TDSY
Sbjct: 1   MDKILLGHGSGGKLMYELIKKYIAPIFELPSLM---DSAIVSLNH----SGKIAITTDSY 53

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IG LAI GT ND+AV GA+P YL+ GFILEEG P+   + +++S++ +A
Sbjct: 54  TVSPIFFPGGDIGDLAINGTVNDLAVVGAVPLYLTVGFILEEGFPLSDFEKILSSISSSA 113

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           + AG+ IV GDTKVV +G  D +FINT+G+G IP  +      +  GD +L+SG++G+HG
Sbjct: 114 KKAGVKIVAGDTKVVDKGKGDGIFINTSGIGVIPEGVELSPLKIEMGDKILISGSIGNHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLI-QTLRDI-PGVKALRDATRGGVNAVVHEFAAAC 238
             +++ R     +  ++SD   L  LI Q +++  P VK +RD TRGG+   + E A   
Sbjct: 174 IAVMSERNGFTFEPPVLSDTRALNGLIDQIMKEFTPFVKVMRDPTRGGLATTLKELALES 233

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
              I + E+A+P+   V+G CELLGLD L  ANEG  V  V+ + AE++L  + SHP G+
Sbjct: 234 LKDILIYESAIPLHDTVKGACELLGLDPLYVANEGIFVAIVKADVAEKILQLMKSHPFGE 293

Query: 299 DAALIGEVVERKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
           ++A+IGEV  + G V L    G  R +D+   E LPRIC
Sbjct: 294 ESAIIGEVTGKGGKVLLKTFIGGTRIVDMLPGEQLPRIC 332


>UniRef50_B4S328 Hydrogenase expression/formation protein HypE n=2
           Tax=Proteobacteria RepID=B4S328_ALTMD
          Length = 350

 Score =  256 bits (655), Expect = 6e-67,   Method: Compositional matrix adjust.
 Identities = 144/338 (42%), Positives = 203/338 (60%), Gaps = 10/338 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
           +IQLA G+GG   ++LI+ +F         A ++     D A +  +G  L+ +TDS+V+
Sbjct: 19  SIQLAQGNGGTLTKRLIDHVFKNK------ANKDLDLLHDAATVTFDGPYLSITTDSFVV 72

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            P  FPGGN+G L++ GT ND+AV GA PRY+S  FI+EEG  + TLK +V  M + A  
Sbjct: 73  SPPTFPGGNVGALSVYGTVNDLAVVGATPRYISTAFIIEEGFSLSTLKQIVNGMHQAAEE 132

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
             +AIVTGDTKVV +G+   +FINT G+G       W    + AGD +LVSG++GDHGA 
Sbjct: 133 TKVAIVTGDTKVVPKGSGGGVFINTTGVGDSRDAPIWDTSLIKAGDHVLVSGSVGDHGAC 192

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           +L  RE  GL G+L SDC  + PLI  ++ + GV+ +RD TRGG++ ++H+ A   G  I
Sbjct: 193 VLLAREDYGLQGQLKSDCGSVVPLIDPIKHLEGVRFVRDPTRGGLSVLLHDVANETGFDI 252

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           EL E  +PV+P V  VCE+LG D    A EG++V  V  + + +VL    S   G+ A  
Sbjct: 253 ELIENNIPVRPEVASVCEILGFDPFVLACEGRIVAVVAPDISGKVLEHWRSIRNGEQAEH 312

Query: 303 IGEVV---ERKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
           IG +V   E KG V +    G +R ++    EPLPRIC
Sbjct: 313 IGVIVKNTESKGRVTIVTPMGGRRFMNELEDEPLPRIC 350


>UniRef50_A7I1Q2 Hydrogenase expression/formation protein HypE n=24
           Tax=Epsilonproteobacteria RepID=A7I1Q2_CAMHC
          Length = 390

 Score =  254 bits (650), Expect = 3e-66,   Method: Compositional matrix adjust.
 Identities = 151/391 (38%), Positives = 213/391 (54%), Gaps = 63/391 (16%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQA------------------------ 39
           I L+HG GG+ M  LIN    +AF N  L    D A                        
Sbjct: 5   ILLSHGGGGEEMNSLINDTIFKAFDNEILRRANDSAILNFPLDLDKNFDIISANFGDKTD 64

Query: 40  -------RLDLAQLVAEGD----------------------RLAFSTDSYVIDPLFFPGG 70
                    D++ L  +                         LAF+TDS+V+ PLFF GG
Sbjct: 65  YFNEKSQNFDVSNLNGQNKTDNMNFNVQNCHNKKNTQILCGNLAFTTDSFVVTPLFFNGG 124

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IGK+A+CGT ND+A+ GA P +LSC FI+EEGL ++T + ++ SMA+TA+ AG+ IV G
Sbjct: 125 DIGKIAVCGTVNDLAMVGAKPLFLSCAFIIEEGLEIDTFERILNSMAKTAKEAGVKIVCG 184

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQT--LTAGDVLLVSGTLGDHGATILNLRE 188
           DTKVV RG+ D++FINT+G+G I   +  G Q   +  G  +L+SG +G HGA I+  R+
Sbjct: 185 DTKVVPRGSGDQIFINTSGIGQI---LKAGVQMDCVKKGAKVLISGDIGRHGAVIMAARD 241

Query: 189 QLGLDGELVSDCAVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           ++ +  +L SDC  L   + + L++   + ALRDATRGG++AV++EFA    C I + E 
Sbjct: 242 EISVSTDLKSDCKPLNAAVTELLKNDVKILALRDATRGGLSAVLNEFAQHLNCEISIREN 301

Query: 248 ALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
            + V P V G+CELLG +  + ANEG  V  +E     + L  L      ++AA+IGEV 
Sbjct: 302 DIKVAPEVLGICELLGFEPYDLANEGTFVAFIEDGDEIKALEILRK--FNENAAIIGEVT 359

Query: 308 --ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
             E+  V L   YG +R L+ P  E LPRIC
Sbjct: 360 QNEKGRVILQNAYGTERFLEFPKGELLPRIC 390


>UniRef50_A4CGN3 Hydrogenase expression/formation protein HypE n=2
           Tax=Flavobacteriaceae RepID=A4CGN3_9FLAO
          Length = 339

 Score =  254 bits (649), Expect = 3e-66,   Method: Compositional matrix adjust.
 Identities = 147/337 (43%), Positives = 200/337 (59%), Gaps = 10/337 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L HGSGG    +L++S     F N  L     Q R D A L  EG + AF+TDS+VI 
Sbjct: 9   ITLGHGSGGLLTNKLLDSGVFHLFDNEHL-----QQRHDGAMLTLEG-KTAFTTDSFVIS 62

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+FFP  NIG+LA+ GT ND+A+ GAIP+YLS  FILEEGL M     ++ S+   A  A
Sbjct: 63  PIFFPDSNIGELAVNGTVNDLAMCGAIPQYLSLSFILEEGLKMTEFWEILVSIKSAAEQA 122

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            I IVTGDTKVV+RG  DK+FINT G+G + A        +  GD ++VS ++  HG  I
Sbjct: 123 NIQIVTGDTKVVERGKGDKIFINTTGIGQLHAKADIAPSNVQPGDKIIVSDSIATHGVAI 182

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKA--LRDATRGGVNAVVHEFAAACGCG 241
           +++RE L  + EL SD   L+ ++  L D  GV    L+D TRGGV  V++E A     G
Sbjct: 183 MSVREGLEFESELKSDTRGLSHMVSELLDTFGVDIHLLKDPTRGGVATVLNEIARDRNLG 242

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IE+ +  LP++  V  +CE+LGLD L  ANEG  +  V+   +E+V+  L S   G +A+
Sbjct: 243 IEILQKDLPLQNEVSALCEILGLDPLYVANEGIFIAVVKDAISEKVVEKLQSMEYGANAS 302

Query: 302 LIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG+V E   K V L    G +R +++   E LPRIC
Sbjct: 303 IIGDVTENHPKQVVLKSAIGGRRIVNMLAGEQLPRIC 339


>UniRef50_B7JF80 Hydrogenase expression/formation protein HypE n=32 Tax=Bacteria
           RepID=B7JF80_BACC0
          Length = 342

 Score =  254 bits (649), Expect = 3e-66,   Method: Compositional matrix adjust.
 Identities = 135/341 (39%), Positives = 210/341 (61%), Gaps = 10/341 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           + NI L HG+GG   Q LI+S+         L + ED A L+++       RLA +TDS+
Sbjct: 7   LENIILDHGTGGLLSQDLISSIITAKLEGVHLGKMEDSAILEVSS-----RRLAMTTDSF 61

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           VIDP+FF  GNIGK+A+CGT ND+AVSGA P YLS   +LEEG P++ L+ ++ S+ ETA
Sbjct: 62  VIDPIFFGEGNIGKVAVCGTVNDLAVSGAKPLYLSLALVLEEGFPIKDLEEILDSIRETA 121

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH-WGAQTLTAGDVLLVSGTLGDH 179
           + AG+ IV GDTKVV++G VDK+FINT G+G    ++  +   ++  GD ++++G LG+H
Sbjct: 122 KEAGVYIVAGDTKVVKKGEVDKIFINTTGIGVFEGDVSPFSVNSIQEGDDIIITGQLGNH 181

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAA 237
              IL++RE LG +  + SDCA L  +I  L++  G  +  +RD TRGG+  V++E +  
Sbjct: 182 SIHILSIREGLGFEQRINSDCAPLNHMITELKNHFGDSIHCMRDITRGGLGTVLNEVSET 241

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
              GI++ E  +P+        ++LG++ +  ANEG + + V    +E+V+  L +   G
Sbjct: 242 INTGIKIQEKDIPMLAETIMAADMLGVNPMYLANEGNVCMFVSPEVSEEVVRVLKNTKYG 301

Query: 298 KDAALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           K+AA+IG+V + K   V +    G  + ++L +   LPR+C
Sbjct: 302 KEAAVIGKVTQTKERQVLMEAKSGELKLIELLYGAELPRLC 342


>UniRef50_D1A5C3 Hydrogenase expression/formation protein HypE n=2
           Tax=Actinomycetales RepID=D1A5C3_THECD
          Length = 437

 Score =  254 bits (648), Expect = 4e-66,   Method: Compositional matrix adjust.
 Identities = 149/301 (49%), Positives = 195/301 (64%), Gaps = 4/301 (1%)

Query: 39  ARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGF 98
           AR+  A   A G RLAF+TDSYV+ PLFFPGG+IG LA+ GT ND+AV GA P YLS GF
Sbjct: 138 ARMSDAMATA-GPRLAFTTDSYVVSPLFFPGGDIGDLAVNGTVNDLAVCGARPLYLSAGF 196

Query: 99  ILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH 158
           ILEEG  +  L+ ++ SMA  A+ AG+ IVTGDTKVV RG  D  +I TAG+G +   I 
Sbjct: 197 ILEEGFEVADLQRIIASMAAAAQRAGVQIVTGDTKVVGRGKADGCYITTAGVGLLDRPIT 256

Query: 159 WGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVK 217
             A T+  GD +LVSG +G+HG TI+  R +L ++ +L SD A L  L + L +   GV+
Sbjct: 257 LDAATVRPGDAVLVSGPIGEHGVTIMLARGELDIEADLTSDTAPLNGLTEALLNATAGVR 316

Query: 218 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVI 277
            LRDATRGGV  V++E A A    I + EAA+P++P V G CELLG+D L  A EG+ V 
Sbjct: 317 VLRDATRGGVATVLNEIAQASQTAIVVDEAAVPIRPVVAGACELLGIDPLYVACEGRFVA 376

Query: 278 AVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAG--LYGVKRTLDLPHAEPLPRI 335
            V+   A++ L  L +HPLG+DAA+IG V +     + G   +G  R +D    +PLPRI
Sbjct: 377 IVDGAHADKALTVLQTHPLGRDAAIIGHVHDDPPSLVLGRTAFGGTRVIDTLVGDPLPRI 436

Query: 336 C 336
           C
Sbjct: 437 C 437



 Score = 49.3 bits (116), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 23/42 (54%), Positives = 28/42 (66%)

Query: 2  NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDL 43
            I LAHG+GG+A Q L+ SLF+ AF NP L   +D A LDL
Sbjct: 24 ERITLAHGAGGKATQSLVESLFVAAFRNPALERLDDGAVLDL 65


>UniRef50_C8PGA7 Hydrogenase expression/formation protein HypE n=1 Tax=Campylobacter
           gracilis RM3268 RepID=C8PGA7_9PROT
          Length = 395

 Score =  253 bits (647), Expect = 6e-66,   Method: Compositional matrix adjust.
 Identities = 164/402 (40%), Positives = 219/402 (54%), Gaps = 73/402 (18%)

Query: 1   MN-NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDL---------------A 44
           MN  I L+HG GG+ M +LIN +   AF N  L    D A L+L                
Sbjct: 1   MNETILLSHGGGGEEMNRLINEMIFAAFDNEILRANNDSAILNLDAGAGFDRTAPSSALN 60

Query: 45  QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGL 104
              + G  LAFSTDS+V+ PLFF GG+IGK+A+CGT ND+A+ GA P +LSC  I+EEGL
Sbjct: 61  SAASFGGELAFSTDSFVVTPLFFNGGDIGKIAVCGTVNDLAMVGAKPLFLSCALIIEEGL 120

Query: 105 PMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAI--PANIHWGAQ 162
            +  L+ ++ SMA TAR+ G+ +V GDTKVV RG  DK+FINT+G+G +  PA +    Q
Sbjct: 121 SLSELRRILDSMASTARSCGVRVVCGDTKVVPRGKCDKIFINTSGIGRVLRPARV----Q 176

Query: 163 TLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVK--ALR 220
            + AG  +L+SG +G HGA IL +R+++ L  EL SDC  L   ++ L  + GVK  A+R
Sbjct: 177 NIKAGAKILLSGDIGRHGAVILAVRDEIALSSELQSDCKPLCAAVEELI-LQGVKIQAMR 235

Query: 221 DATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVE 280
           DATRGG++AV++EFA++ G    + E  + +   V GVCELLG +    ANEG  V  VE
Sbjct: 236 DATRGGLSAVLNEFASSSGLEFLVREEDIKISDEVVGVCELLGFEPYELANEGTFVAIVE 295

Query: 281 RNA-AEQVLAALHSHPLGKDAALIGEVVE------------------------------- 308
            +A A + L  L       +AA+IGEV E                               
Sbjct: 296 DDAEANRALEILRE--FDANAAIIGEVREVGHDKGEFKGSLAPKLGTWDESTGASDAGTV 353

Query: 309 ---RKG-----------VRLAGLYGVKRTLDLPHAEPLPRIC 336
              R G           V L   YG +R L+LP  E LPRIC
Sbjct: 354 SENRAGQFQTPHATKGRVILQNAYGSQRFLELPKGELLPRIC 395


>UniRef50_C9KK60 Hydrogenase expression/formation protein HypE n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KK60_9FIRM
          Length = 348

 Score =  250 bits (639), Expect = 5e-65,   Method: Compositional matrix adjust.
 Identities = 152/340 (44%), Positives = 197/340 (57%), Gaps = 9/340 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG+GG+    LI  +F   F NP     +D A L +        R AF+TD +++
Sbjct: 12  RVTLAHGAGGRQTAALIARVFARHFQNPDFT-ADDAAILPVGNFAT--GRTAFTTDGFIV 68

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            P  FPGGNIGKL+ICGT ND+A  GA+PRYLSC F +EEG P+  L A+  +MAETA+A
Sbjct: 69  SPWQFPGGNIGKLSICGTVNDLACMGAVPRYLSCAFQIEEGFPLRDLDAIAAAMAETAKA 128

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ IV GDTKV  RG VD +FI T G+G +  +         AGD ++V+G +G HGA 
Sbjct: 129 AGVRIVAGDTKVAGRGQVDGVFITTTGLGELLPDAEPSGSRAEAGDAIIVTGDVGRHGAA 188

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTL----RDIPGVKALRDATRGGVNAVVHEFAAAC 238
           IL  R    +D  + SDCA L   ++ L     D   +  +RDATRGGV  V+HE AA  
Sbjct: 189 ILVARRDFAIDAAITSDCAPLAATVRALFAAVPDKSAIHTIRDATRGGVGTVLHEIAAES 248

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GIEL   A+PV P VRGVC LLGL+ L  A EG+LV+   +  A +++  L + P  +
Sbjct: 249 HVGIELDAPAIPVAPEVRGVCGLLGLEPLYLACEGRLVLFAPQAIAPKLVETLRALPDSR 308

Query: 299 DAALIGEVVERKGVR--LAGLYGVKRTLDLPHAEPLPRIC 336
            AA+IG V      R  L    G K  L  P  E LPRIC
Sbjct: 309 QAAIIGHVTPDFSGRVVLRTEIGTKTLLPEPSGELLPRIC 348


>UniRef50_A8ZNR3 Hydrogenase expression/formation protein HypE n=17 Tax=Bacteria
           RepID=A8ZNR3_ACAM1
          Length = 362

 Score =  249 bits (635), Expect = 1e-64,   Method: Compositional matrix adjust.
 Identities = 153/359 (42%), Positives = 202/359 (56%), Gaps = 38/359 (10%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG GG+ M QLI  +F   F      + ED+   D A L     RLA +TDSYV+
Sbjct: 17  QVLLAHGGGGKLMHQLIEQMFGRLF------QSEDRHHHDAAVLGVPPGRLALTTDSYVV 70

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LA+ GT ND+A++GA P YLS  FILEEGL M TL  VV SM + A  
Sbjct: 71  HPLFFPGGDIGSLAVYGTVNDLAMAGARPLYLSTSFILEEGLSMTTLWQVVQSMQQAAHQ 130

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A + IVTGDTKVV+RG  D +FINTAG+G I  +     Q++  GD+++++G LG HG  
Sbjct: 131 ADVQIVTGDTKVVERGKGDGVFINTAGVGIIEHHQTIHPQSIQPGDLVILNGDLGRHGMA 190

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDI--PGVK--ALRDATRGGVNAVVHEFAAAC 238
           +L  RE L  + E+ SD A   PL   + D+   GV+   +RD TRGG+ + ++E A A 
Sbjct: 191 VLAEREGLEFESEIKSDSA---PLNHVVLDLFAHGVELHCMRDLTRGGLASALNEIALAT 247

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAAL------- 291
           G  I L E  +P++  V+G CE+LG D L  ANEG+ +  V   + +  LA L       
Sbjct: 248 GVAISLDETCIPIREDVQGACEILGFDPLYVANEGRFIAFVPPQSVDLALARLNAPLSFP 307

Query: 292 ------------HSHPLGKDAALIGEVVERKGVR--LAGLYGVKRTLDLPHAEPLPRIC 336
                       H HP    A +IG+V      R  L    GV+R +D    E LPRIC
Sbjct: 308 LSGQSDTHPQMRHQHP----AQVIGQVTTTTSPRVTLTNRLGVERIVDFLSGEQLPRIC 362


>UniRef50_A4XJQ3 Hydrogenase expression/formation protein HypE n=9 Tax=Clostridia
           RepID=A4XJQ3_CALS8
          Length = 336

 Score =  248 bits (634), Expect = 2e-64,   Method: Compositional matrix adjust.
 Identities = 133/339 (39%), Positives = 195/339 (57%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  IQ  HG+GG+   +LIN LF   F +  L   +D +  DLA       ++  +TDS+
Sbjct: 5   MKFIQKEHGNGGKQTYELINELFKPIFDSEILKRGDDSSIFDLAS-----KKIGVTTDSF 59

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FF GG+IGKL++CGT ND+AVSG +P+Y++  FI+EEG P+  L+ +V SM E A
Sbjct: 60  VVKPYFFKGGDIGKLSVCGTVNDLAVSGLVPKYITASFIIEEGFPIVDLQKIVKSMKEYA 119

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGA-QTLTAGDVLLVSGTLGDH 179
             AG+ IV GDTKVV++G+ D +FINT G G       + + + +  G V+LVSG +G H
Sbjct: 120 DIAGVEIVAGDTKVVEKGSCDGIFINTTGFGVCEKEEKFPSIEKIKGGQVILVSGDIGRH 179

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
           GA I +   + G + ++ SDCA L  +I  L +   +  ++D TRGG+   ++E A    
Sbjct: 180 GACIYSHNSEFGFEEKIESDCAPLNRVINELLENVEICYMKDLTRGGLATALNEIAQKAN 239

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I + E  +PV   V+ +C++LGLD    A EG+ V  V R   ++ L  L  +   K+
Sbjct: 240 VAIYVEEDKVPVSNEVKALCDILGLDWYYLACEGRFVAIVNRKNEQRALEILRKY--NKE 297

Query: 300 AALIG--EVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A  IG  E  E   V L   +G  R LD+ + + LPRIC
Sbjct: 298 ACEIGWIEDTEENRVYLRTSFGGTRILDMLYYDMLPRIC 336


>UniRef50_C1SLC8 Hydrogenase expression/formation protein HypE n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SLC8_9BACT
          Length = 327

 Score =  247 bits (630), Expect = 5e-64,   Method: Compositional matrix adjust.
 Identities = 141/336 (41%), Positives = 199/336 (59%), Gaps = 9/336 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I +A GSGG + +  ++ +      N  L +  D A      +V+   R AF+TDSY
Sbjct: 1   MEKITMAVGSGGTSSRSFVSEIIFSRLGNEHLLKASDAA------IVSTSGRTAFTTDSY 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FFPGGNIGK+A+CGT ND+ VSGA P YLS G I+ EG P+  L+ V+ SMAE  
Sbjct: 55  VVRPEFFPGGNIGKIAVCGTINDLLVSGAKPLYLSFGLIMPEGYPVADLERVIDSMAEEC 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           R A + IV GDTKVV +G  D L INT+G+G    + +     +  GD ++++  +  HG
Sbjct: 115 RKADVKIVCGDTKVVDKGGCDGLIINTSGIGESLRD-YTEPYNIQEGDAVILTSDVARHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
            +++  R +LG DGE++SDCA L  +   + ++  VK  RDATRGGV AV++E A+  G 
Sbjct: 174 MSVMLARGELGFDGEVLSDCACLKDVFSAVENL-NVKFARDATRGGVAAVLNEIASDSGK 232

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G  + E  +P+   V  +C++LG D L  ANEG  VI V    AE+ L+ + +   G+ A
Sbjct: 233 GFLMRETDIPMDENVGYLCDMLGFDPLAVANEGLAVIIVSEEDAEKALSNICACENGQRA 292

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A+ G  VE K V L    G KR +++P  E LPRIC
Sbjct: 293 AIAGR-VEGKNVILETSIGGKRHIEMPAGELLPRIC 327


>UniRef50_A4TCL4 Hydrogenase expression/formation protein HypE n=15 Tax=Bacteria
           RepID=A4TCL4_MYCGI
          Length = 373

 Score =  246 bits (628), Expect = 8e-64,   Method: Compositional matrix adjust.
 Identities = 143/323 (44%), Positives = 197/323 (60%), Gaps = 8/323 (2%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLA 76
           +L+  LF+ AF +   A   D A +++      G RLAFSTDS+V+ P+ FPGG IG LA
Sbjct: 56  ELVEHLFLPAFGSAAEAGLADSAVVEIG-----GARLAFSTDSFVVKPMVFPGGTIGDLA 110

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           + GT ND+A++GA+P  LS  FILEEG  ++ L  V  ++   A AAG+ +VTGDTKVV 
Sbjct: 111 VNGTVNDLAMAGAVPAVLSTAFILEEGTALDHLARVAQAVGTAALAAGVKLVTGDTKVVD 170

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGEL 196
            G  D ++INT G+G +   +    Q    GDV++VSG LG HG  +L+ RE L     +
Sbjct: 171 SGHGDGVYINTTGIGLVDPRVDIRPQRAAPGDVVIVSGDLGVHGIAVLSCREGLEFATSV 230

Query: 197 VSDCAVLTPLIQTLRDI-PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAV 255
            SD A L  L+  + +    +  LRD TRGG+ A ++E A A G G+ +++ ALP+   V
Sbjct: 231 ASDAAPLHGLVAAMVETGADIHTLRDPTRGGLAATLNEIARAAGVGVSIADTALPIPQEV 290

Query: 256 RGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV-ERKGVRL 314
           R  C +LGLD L  ANEGKLV  V    A++VLAA+H+HPLG  +A+IG  V +  G+ +
Sbjct: 291 RDACSMLGLDPLYVANEGKLVAFVPAADADEVLAAMHAHPLGAQSAVIGTCVPDHPGMVV 350

Query: 315 AGL-YGVKRTLDLPHAEPLPRIC 336
           A    G  R +DLP  E LPRIC
Sbjct: 351 AKTALGGNRVVDLPIGEQLPRIC 373


>UniRef50_C9LR03 Hydrogenase expression/formation protein HypE n=1 Tax=Dialister
           invisus DSM 15470 RepID=C9LR03_9FIRM
          Length = 327

 Score =  246 bits (627), Expect = 1e-63,   Method: Compositional matrix adjust.
 Identities = 144/337 (42%), Positives = 202/337 (59%), Gaps = 14/337 (4%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            I L HGSGG+   +LI  +F   F +  L + ED A L              ++DS+V+
Sbjct: 2   KITLKHGSGGEESGRLIKDIFASVFDDEILLKMEDSAVLPPLH-----GNPVLTSDSFVV 56

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           +PLFF GG+IGKL++CGT ND++  GA P YL+  FILE GL  + L  +V SM ETA  
Sbjct: 57  EPLFFKGGDIGKLSVCGTVNDLSSMGARPLYLTASFILETGLDTDILGKIVQSMKETAEE 116

Query: 123 AGIAIVTGDTKVVQ-RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           AG+ IV GDTKV++ +G    L+INTAG+G  P++     + + +GD L+++GTLGDH A
Sbjct: 117 AGVRIVAGDTKVIEGKGG---LYINTAGVGERPSSRDISCRNMKSGDTLILTGTLGDHHA 173

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACGC 240
            +L  R  LG++ E+ SDCA L  +++ L +    V  +RD TRGG+  V +E A +   
Sbjct: 174 AVLTNR--LGIESEIESDCAPLNHMVEELLEGNISVHTVRDITRGGLATVANELAVSSSV 231

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
            IEL E  +PV   V+G   +LGLD L   NEGK++IAV    AE+ +  L  +  G++A
Sbjct: 232 RIELEEELIPVSDIVQGFTGILGLDPLTMGNEGKMIIAVSPKDAEKAVGILRRNKYGRNA 291

Query: 301 ALIGEVVERKGVRL-AGLYGVKRTLDLPHAEPLPRIC 336
              G+V+E KGV L   L G++R L L   E LPRIC
Sbjct: 292 VAAGQVLEGKGVYLRTALGGLRRVLPL-RGEGLPRIC 327


>UniRef50_B2UW48 Hydrogenase expression/formation protein n=12 Tax=Helicobacter
           RepID=B2UW48_HELPS
          Length = 332

 Score =  245 bits (625), Expect = 2e-63,   Method: Compositional matrix adjust.
 Identities = 140/341 (41%), Positives = 208/341 (60%), Gaps = 14/341 (4%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+++ LA G+GG+    LI  +FM     P+L E       D  +  A G+    STDS+
Sbjct: 1   MDSVTLACGNGGKETNALIERVFM-----PYLKEFIVAFDEDAPKFKASGE-YCVSTDSF 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           VI PL F GG+IGKL +CG+ANDV+V G  P YL+ GFILEEGL +  LK ++ S+ +  
Sbjct: 55  VITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKEL 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMG-AIPANIHWGAQTLTAGDVLLVSGTLGDH 179
             A + +++ DTKVV +G+VDKLFINT  +G  I   I   ++ L  G  +++S T+ +H
Sbjct: 115 LKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKPGI--SSRYLKQGQAIIISDTIANH 172

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHEFAAA 237
           GA++  +R ++ L   L SDC +L PL++   L D+  + ALRDATRGG+ +V++E+A +
Sbjct: 173 GASLFAMRHEIKLKTNLESDCQLLYPLLKPLFLSDL-KIHALRDATRGGLASVLNEWANS 231

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
               I + E  +P+K   +G+CE+LGL+    ANEG  V+A+ +  A + L  L S+   
Sbjct: 232 SKVKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKA 291

Query: 298 KDAALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           K+A +IGEV E     V L   +G +R L++P  E LPRIC
Sbjct: 292 KNACVIGEVFENPYPSVVLKNAWGFERILEMPEGELLPRIC 332


>UniRef50_A7H7N3 Hydrogenase expression/formation protein HypE n=1
           Tax=Anaeromyxobacter sp. Fw109-5 RepID=A7H7N3_ANADF
          Length = 340

 Score =  243 bits (619), Expect = 9e-63,   Method: Compositional matrix adjust.
 Identities = 158/339 (46%), Positives = 211/339 (62%), Gaps = 10/339 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYV 61
            I L HGSGG+AM+QLI  +F+   A+P   +    + LD    +  GDR L  +TDS+V
Sbjct: 7   KIGLKHGSGGRAMRQLIEDVFL-TLASP--VDGIGLSALDDGAAIRVGDRWLVVTTDSHV 63

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAI-PRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           + P+FFPGG+IG+L++ GT ND+A+ GA  P  L+C  +LE+G P   L+ VV SM ETA
Sbjct: 64  VHPIFFPGGDIGRLSVSGTVNDLAMMGATEPLGLTCAVVLEDGFPRADLERVVASMRETA 123

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           R A   IVTGDTKV+ +  VD + +NT G+ A+   +   A  L AGD+L+V+GT+GDHG
Sbjct: 124 REANAPIVTGDTKVMGKDEVDGIVLNTTGV-ALAERVVSDAG-LRAGDLLIVTGTIGDHG 181

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAAC 238
             I++ R  L L+G+L SD A L  L++      G  V A++D TRGGV  V+HE AA  
Sbjct: 182 MAIMSRRHDLRLEGDLRSDVAPLNGLVREALRAGGEDVVAMKDPTRGGVAGVLHEMAAKG 241

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI + E ALPV+  VR   E++G+D L  ANEGK VIAV   AA++VLAAL +HPLG 
Sbjct: 242 KVGIVIDETALPVRDEVRAAGEMIGIDPLLVANEGKAVIAVRARAADKVLAALRAHPLGA 301

Query: 299 DAALIGE-VVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            A +I   + ER G  +      KR L  P  E LPRIC
Sbjct: 302 SATVIATAIAERPGAVILDTGFGKRMLAEPEGELLPRIC 340


>UniRef50_D1VJK8 Hydrogenase expression/formation protein HypE n=1 Tax=Frankia sp.
           EuI1c RepID=D1VJK8_9ACTO
          Length = 409

 Score =  242 bits (617), Expect = 1e-62,   Method: Compositional matrix adjust.
 Identities = 170/388 (43%), Positives = 222/388 (57%), Gaps = 62/388 (15%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
            +I +AHG+GG+A   L++++F+EAF NP L   +D A +D     A G RL  +TDSYV
Sbjct: 31  EHITMAHGAGGKATAALVDAVFLEAFRNPALEALDDGAHVD-----AGGARLVLTTDSYV 85

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG IG LA+ GT ND+AV GA P YL+CGF+LEEG  +  L+ VV +MAE AR
Sbjct: 86  VTPLFFPGGCIGDLAVNGTVNDLAVCGAKPLYLTCGFVLEEGFAVADLRRVVAAMAEAAR 145

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLT---------------- 165
            AG+ +VTGDTKVV RG  D  ++NT G+G      H G  TL                 
Sbjct: 146 TAGVTLVTGDTKVVPRGRADGCYVNTTGLGL----FHPGGSTLDDESPMEGVVAADDPVG 201

Query: 166 ----------------------------AGDVLLVSGTLGDHGATILNLREQLGLDGELV 197
                                        GDV+LVSG +GDHG TI+  R +L L+ +L 
Sbjct: 202 PWPVGYTPPGHRPTEPDRLDRLGMAHARPGDVVLVSGPIGDHGITIMLARGELDLEADLR 261

Query: 198 SDCAVLTPLIQTLRDIP-------GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
           SD A L+ L++ L           GV+A+RDATRGGV  V++E A A G G+ + E A+P
Sbjct: 262 SDTAPLSGLVERLLTATSGPEHGGGVRAMRDATRGGVATVLNELAMAAGVGVVIDEDAVP 321

Query: 251 VKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
           V+ AVRG  ELLG+D L  A EG+LV  V   AA+  LAAL + PLG  A +IG VV+  
Sbjct: 322 VREAVRGAAELLGIDPLYVACEGRLVAVVAPEAADAALAALLADPLGAGATVIGRVVDDP 381

Query: 311 G--VRLAGLYGVKRTLDLPHAEPLPRIC 336
              V L   +G  R +D+   +PLPRIC
Sbjct: 382 PGLVLLNTAFGGTRIVDMLVGDPLPRIC 409


>UniRef50_C3XF65 Hydrogenase expression/formation protein n=3 Tax=Helicobacter
           RepID=C3XF65_9HELI
          Length = 361

 Score =  239 bits (610), Expect = 1e-61,   Method: Compositional matrix adjust.
 Identities = 139/368 (37%), Positives = 210/368 (57%), Gaps = 39/368 (10%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGD-RLAFSTDS 59
           M+ + LAHGSGG    + +  +FM     P+  +    A  D     +  D +   STDS
Sbjct: 1   MDIVTLAHGSGGINAAEFVQKVFM-----PYFKDLMPYANEDCGIFSSIKDMKYVTSTDS 55

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           Y I+P+FF GGNIGKL +CG++NDVA+ G  P YL+ GFI+EEG  ++ LK +  S+A  
Sbjct: 56  YTINPIFFAGGNIGKLCVCGSSNDVAMMGGKPLYLNIGFIIEEGFNIDLLKQIAESIALE 115

Query: 120 ARAAGIAIVTGDTKVVQR-----GAVDKL-FINTAGMGAIPANIHWGAQTLTAGDVLLVS 173
            ++  I I++ DTKV+ +      A DKL FINT  +G++  +    A+ L+  D +++S
Sbjct: 116 CKSLNIKILSADTKVLPKVTDSTEAKDKLIFINTTCIGSVEKDC-ISAKNLSENDSIILS 174

Query: 174 GTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTL--RDIPGVKALRDATRGGVNAVV 231
           G +G HGA I   +  + +   + SDCA L P++++L   +IP + A+RDATRGG+++V+
Sbjct: 175 GKIGSHGARIFLEQNNIAITSNIQSDCASLYPMLESLLQSNIP-IHAMRDATRGGLSSVL 233

Query: 232 HEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAAL 291
           +E+A +    I++ E  + +   V GVCE+LGL+  + ANEG  VIA+ +  AE+VL+ L
Sbjct: 234 NEWAISSHACIDIYEEKIQIDSEVHGVCEMLGLEPYDLANEGVCVIAMPKQYAEEVLSLL 293

Query: 292 HSHPLGKDAALIGEVVE-----------------------RKGVRLAGLYGVKRTLDLPH 328
             H LG +A +IGEV +                        + V L   YG KR L+ P 
Sbjct: 294 RGHTLGVNATIIGEVSKVFNPIFNLQDSKDNKAQISKTTYHQKVVLHTKYGSKRFLEYPQ 353

Query: 329 AEPLPRIC 336
            E LPRIC
Sbjct: 354 GELLPRIC 361


>UniRef50_B4U670 Hydrogenase expression/formation protein HypE n=2 Tax=Bacteria
           RepID=B4U670_HYDS0
          Length = 328

 Score =  238 bits (608), Expect = 2e-61,   Method: Compositional matrix adjust.
 Identities = 125/336 (37%), Positives = 205/336 (61%), Gaps = 13/336 (3%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           ++L+HG G +  ++LI  +F++   N  L+ ++       A ++    +LA STDS+ ++
Sbjct: 3   VKLSHGGGAKETRELIEKIFLKHLKNDLLSNED-------ATILHLDGKLAISTDSFTVN 55

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+FF GG+IGKL++ G  ND++V GA P Y+S GFI+EEGL  E L+ +V S+ E A+  
Sbjct: 56  PIFFKGGDIGKLSVAGVVNDLSVMGAKPLYMSMGFIIEEGLAFEELERIVISIKEEAQKT 115

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           GI ++T DTKVV +G  DK++IN  G+G +       A  L  GD ++VSG +G+HGA I
Sbjct: 116 GIKLITADTKVVPKGLCDKIYINATGIGKLIKE-GISASNLQEGDAIVVSGPIGNHGAVI 174

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQ-TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           +  R   G D ++ SDCA L   I+  L++   + A+RD TRGG+ + ++E + +    I
Sbjct: 175 MAHRN--GFDIDINSDCASLWEAIEPLLKENIEIHAMRDLTRGGLASALNELSQSSKVEI 232

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            + E  +P++ +V+G CE+LG++  + A EG  V+++ +   ++ L  L S  L + A +
Sbjct: 233 LIKEEDIPIEDSVKGFCEILGIEPFSLACEGTFVMSIPKKDVQKALDILKSQKLTQKAKV 292

Query: 303 IGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           IGE+++  ++G  +  LYG  R L+    E LPRIC
Sbjct: 293 IGEIIKKGKQGAYIQTLYGSVRYLEEAPGELLPRIC 328


>UniRef50_Q58089 Putative hydrogenase expression/formation protein MJ0676 n=40
           Tax=cellular organisms RepID=Y676_METJA
          Length = 335

 Score =  236 bits (602), Expect = 8e-61,   Method: Compositional matrix adjust.
 Identities = 130/337 (38%), Positives = 200/337 (59%), Gaps = 6/337 (1%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYV 61
            I   HG+GG+ MQ+LI  + ++      +        LD +  +  GD+ + F+ D + 
Sbjct: 2   KITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGHT 61

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P+FFPGG+IG+LA+ GT ND+AV GA P  LS   I+ EG  +E L+ +V S+ ET++
Sbjct: 62  VKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETSK 121

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            A +AI+TGDTKV     VD + I+TAG+G +          +  GD ++VSG +G+HG 
Sbjct: 122 EAEVAIITGDTKVSD--GVDDIIISTAGIGIVDRGKAIRDCNVQEGDAIIVSGNIGEHGL 179

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQ-TLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
            IL  RE    +  + SD A +  LI+  L +   + A++D TRGG+   ++E A     
Sbjct: 180 AILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNI 239

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           GI + E  +P+   V+ +C++LGLD L  ANEGK+V+AV++  AE+ L  L  HPLGK+A
Sbjct: 240 GITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNA 299

Query: 301 ALIGEVV-ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            +IG    E KGV +  + G +R +D+P  +P+PR+C
Sbjct: 300 EIIGYATKEHKGVIIETIVG-RRIVDMPIGDPIPRVC 335


>UniRef50_B9KGD0 Hydrogenase expression/formation protein HypE n=1 Tax=Campylobacter
           lari RM2100 RepID=B9KGD0_CAMLR
          Length = 336

 Score =  233 bits (595), Expect = 5e-60,   Method: Compositional matrix adjust.
 Identities = 139/339 (41%), Positives = 193/339 (56%), Gaps = 19/339 (5%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I LAHG GG+ M  LIN +F   F N  L E  D A LD          LAFSTDS+
Sbjct: 14  MKQITLAHGGGGEEMNALINEIF-SIFENDVLKEANDAAILD---------DLAFSTDSF 63

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V++P+F    NIGKLA+CG+ NDV + GA P YLS   ILEEG  +E LK ++ S+ E  
Sbjct: 64  VLNPIFLKDINIGKLAVCGSVNDVLMVGAKPLYLSLALILEEGFEIEKLKIILNSIKEEC 123

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             AG+ +V GDTKVV +   D+++INT+ +G     I+   + L +G  +LVS  +G HG
Sbjct: 124 DKAGVKLVCGDTKVVPKNKGDEIYINTSCIGKNIQKIN--TKNLKSGCSILVSRDIGAHG 181

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDI-PGVKALRDATRGGVNAVVHEFAAACG 239
             +  L E+  L+  + SDC  L   +  L +    +KA+RDATRGG++AV++E++    
Sbjct: 182 CAV--LVERNNLEANIQSDCKSLKNEVLALLNAGISIKAMRDATRGGLSAVLNEWSKLSN 239

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             + + E  +PV   V GVCEL G +    ANEG  +I V++   ++ L  L       +
Sbjct: 240 LELLIYEEKIPVCDEVLGVCELFGYEPYELANEGTFIICVDKKDEQKALKILKQ--FNAN 297

Query: 300 AALIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGE+   E+  V L   YG KR L+ P  E LPRIC
Sbjct: 298 AAIIGEITPNEKARVVLENAYGAKRILETPKGELLPRIC 336


>UniRef50_B5Y920 Hydrogenase expression/formation protein HypE n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y920_COPPD
          Length = 319

 Score =  233 bits (595), Expect = 6e-60,   Method: Compositional matrix adjust.
 Identities = 133/337 (39%), Positives = 198/337 (58%), Gaps = 19/337 (5%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ I L+ G+GG+ M Q     F++    P L E        ++   A  +  AF+ DS+
Sbjct: 1   MDKITLSIGTGGEEMTQ-----FLQKTVFPILEES-------ISGDAALVNHTAFTIDSF 48

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V +P FFPGG+IG LA+ GT ND+  +GA P  L+   ILEEGL ME ++ ++    ETA
Sbjct: 49  VAEPPFFPGGSIGTLAVSGTVNDLVAAGAKPSALALSLILEEGLDMEVVRRILQDAKETA 108

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           + A I IVTGDTKVVQ+GA DK+F+ T+G+G    +    A     GD ++V+G +  HG
Sbjct: 109 KLAQIKIVTGDTKVVQKGAADKVFVTTSGIGQKVLDFESPA----PGDAVVVTGDIARHG 164

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACG 239
           AT+L   ++  L+ +L SDC  L  LI  L+   G +K +RD TRGGV  ++HEF +   
Sbjct: 165 ATMLLASKKFELESQLTSDCEPLCWLIDVLKPFEGFLKWMRDPTRGGVGTILHEFCSQFS 224

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            G+ L +  +P+ P V+G+CELLGL+ L+ A+EG++VI +  + A + L +L   P   +
Sbjct: 225 LGVRLFQKQIPIMPEVKGICELLGLEPLHLASEGRMVIVISPDKAHEFLESL--KPFAPN 282

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A++IGEVV+        + G +  +     E LPRIC
Sbjct: 283 ASVIGEVVDDHKTLTQVVDGYETYVPPLTGEILPRIC 319


>UniRef50_A5EUI7 Hydrogenase expression/formation protein n=4 Tax=Proteobacteria
           RepID=A5EUI7_BRASB
          Length = 346

 Score =  226 bits (576), Expect = 8e-58,   Method: Compositional matrix adjust.
 Identities = 148/335 (44%), Positives = 199/335 (59%), Gaps = 4/335 (1%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG+GG+ M+QLI  LF+    N  L    D A L     +  G     +TD + +
Sbjct: 15  RVSLAHGNGGRRMRQLIEELFVRHLGNALLDTDADAAAL---PPLPTGATPMITTDGFTV 71

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DPL FPGGNIG LA+ GT ND+AVSGA P YL+    LEEGL +  L  +  SMA  A  
Sbjct: 72  DPLEFPGGNIGSLAVHGTVNDLAVSGAEPLYLTLNCFLEEGLDLGLLDRLTASMAAAATE 131

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ +V GDTKVV+RG    +++ T+G+G   A +  G   + AGD +LVSG +GDHG  
Sbjct: 132 AGVKVVAGDTKVVRRGEGGGVYLATSGVGLRRAGLDLGLGRIAAGDHILVSGPVGDHGTA 191

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           +L  R Q GL G+LVSD A + P+ + L D+PG++ +RD TRGG+  V HE     G GI
Sbjct: 192 VLLARGQFGLRGDLVSDSASVLPVTRALVDVPGLRFMRDPTRGGLATVAHEIVRHTGMGI 251

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            LSE A+P++  VR VCE+LG + L  A+EG++V  V+  +A   LAA+       DA  
Sbjct: 252 RLSEPAIPIRDQVRAVCEMLGYNPLYLASEGRVVAVVDPASAPAALAAMRGPGQSPDAVE 311

Query: 303 IGEV-VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           IG V  E   V L    G +R ++   A+PLPRIC
Sbjct: 312 IGTVGCEEPYVVLETEIGGERLIEELEADPLPRIC 346


>UniRef50_C7NVH7 Hydrogenase expression/formation protein HypE n=1 Tax=Halorhabdus
           utahensis DSM 12940 RepID=C7NVH7_HALUD
          Length = 365

 Score =  225 bits (574), Expect = 2e-57,   Method: Compositional matrix adjust.
 Identities = 136/340 (40%), Positives = 197/340 (57%), Gaps = 12/340 (3%)

Query: 4   IQLAHGSGGQAMQQLIN----SLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDS 59
           I  AHG+GG  M +L++    S F +A A+  LA  +D +     Q + +   +  +TDS
Sbjct: 31  ITHAHGAGGGQMTELVDAVAVSQFADAAADVGLAALDDGS----VQPIDDDHSVVVTTDS 86

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAI-PRYLSCGFILEEGLPMETLKAVVTSMAE 118
           +V+ PLFF GG+IG+LA+ GT ND+A+ GA  P  L+   I+E G P  T++ V  SM E
Sbjct: 87  HVVTPLFFRGGDIGRLAVSGTVNDLAMMGATEPLALTSSLIIEAGTPQTTVERVTESMRE 146

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD 178
               AG  + TGDTKV+  G +D L INT G+  +P   H     L+ GD L+VSGT+GD
Sbjct: 147 ACEEAGATVTTGDTKVMGSGEMDTLAINTTGVAVVPKGGHVPDAGLSVGDRLIVSGTVGD 206

Query: 179 HGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAAC 238
           HG ++L+ RE     G+L SD   +  L++   D   V A++D TRGG+  V++E A+  
Sbjct: 207 HGISLLSEREGFDFGGDLESDVQPVNDLVRAAMDAGEVTAMKDPTRGGLATVLNEMASKA 266

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI++ E ++PV   V    E+LG++  + A EG +V+ V    A  VL AL  +P G+
Sbjct: 267 DVGIDVEERSVPVSGPVSSAGEVLGIEPFDVACEGVVVMGVASEDAADVLDALRDNPKGE 326

Query: 299 DAALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           DAA++GEVV+     V L   +G +R L  P  E LPRIC
Sbjct: 327 DAAIVGEVVDDHTGQVVLDTGFG-RRYLSPPEGEQLPRIC 365


>UniRef50_A3Z0T5 Hydrogenase expression/formation protein; HypE n=1
           Tax=Synechococcus sp. WH 5701 RepID=A3Z0T5_9SYNE
          Length = 343

 Score =  218 bits (555), Expect = 2e-55,   Method: Compositional matrix adjust.
 Identities = 144/322 (44%), Positives = 186/322 (57%), Gaps = 10/322 (3%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKL 75
           Q+L+  + + A          D   LD A L  E   LAFSTD +V+ PL FPGG+IG L
Sbjct: 31  QRLLEQVILPALG------ATDGVLLDAASLTTEAGELAFSTDGHVVRPLEFPGGDIGAL 84

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVV 135
           A+ GT ND+A+ GA P  LS G ILEEGLP+  L  V++S A  A   G+++VTGDTKVV
Sbjct: 85  AVFGTVNDLAMLGATPLALSLGLILEEGLPLSILSRVLSSAAAAAARCGVSVVTGDTKVV 144

Query: 136 QRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE 195
           +RG  D LF+ TAG+G IPA +  G   + +GD +LVSG LG HG  IL  RE+LG    
Sbjct: 145 ERGKADGLFMTTAGIGRIPAGVSIGPSAIRSGDAILVSGDLGRHGLAILAAREELGFSTS 204

Query: 196 LVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
           L SD A L   +Q L      + ALRD TRGG+ A +HE     G G  + EA +PV  A
Sbjct: 205 LESDLAPLHGSVQALLAAGLELHALRDLTRGGLAAALHELCRDAGLGGLVHEAVVPVHAA 264

Query: 255 VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
           V   CELLGLD L  A+EG+ V+ +  + A+  L  L        AA+IG  +  + + L
Sbjct: 265 VATACELLGLDPLTMASEGRFVMMLPASQAQDALKLLRHEQ--SSAAVIGR-IGGEALLL 321

Query: 315 AGLYGVKRTLDLPHAEPLPRIC 336
               GV+R L+L   E LPRIC
Sbjct: 322 ETSLGVRRPLELGRGELLPRIC 343


>UniRef50_D2LQB8 Hydrogenase expression/formation protein HypE n=3
           Tax=Aciduliprofundum boonei T469 RepID=D2LQB8_9EURY
          Length = 339

 Score =  211 bits (538), Expect = 2e-53,   Method: Compositional matrix adjust.
 Identities = 121/344 (35%), Positives = 204/344 (59%), Gaps = 15/344 (4%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           ++ I++  G+GG+AM++LI  + ++        +       D A +  +G+ + F+ D +
Sbjct: 3   LDRIRMVDGAGGEAMERLIKEIILDNITLRSAGKVSLDDLDDGATISLDGEDIVFTIDGH 62

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IGKLA+ GT ND+AV GA P  L+   I+E+G  M++LK ++ S+ +T 
Sbjct: 63  TVKPIFFPGGDIGKLAVSGTVNDLAVMGAKPLALAISLIIEDGFSMDSLKNIMISIDKTG 122

Query: 121 RAAGIAIVTGDTKVVQRGAVDK--LFINTAGMGAIPANIH-WGAQTLTAGDVLLVSGTLG 177
           +   + I+TGDTKVV+    DK  +F  +AG+G     +   GA+    GD +L++G +G
Sbjct: 123 KDVPVPIITGDTKVVE----DKIGIFAISAGIGKADKIVRDSGARV---GDFVLINGGIG 175

Query: 178 DHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VKALRDATRGGVNAVVHEF 234
           +HG  I++ RE +  +  LVSD + L  LI+ +    G   + A++D TRGG++  ++E 
Sbjct: 176 EHGFAIMSKREGIDFETSLVSDVSPLWSLIEDVAKCIGWENIHAMKDPTRGGLSEALNEM 235

Query: 235 AAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSH 294
           A+    GIE+ E ++P+K +V+   E+LG+     ANEGK+V+ V     +  + A+  +
Sbjct: 236 ASKANVGIEIDEESVPIKSSVKAASEMLGISPFIMANEGKVVMIVADGYQDDAIEAMRKN 295

Query: 295 PLGKDAALIGEVV-ERKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
             GKDAA+IG V+ E  G V +    G KR ++ P  +P+PR+C
Sbjct: 296 KNGKDAAIIGRVIREYPGKVIIKTKIGGKRFIERPIGDPVPRVC 339


>UniRef50_D1Y5N1 Hydrogenase expression/formation protein HypE n=1
           Tax=Pyramidobacter piscolens W5455 RepID=D1Y5N1_9BACT
          Length = 331

 Score =  209 bits (532), Expect = 1e-52,   Method: Compositional matrix adjust.
 Identities = 143/340 (42%), Positives = 191/340 (56%), Gaps = 20/340 (5%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L  GSGG+    L+ S+ ++ FA    A    +   +    + EG+ LA +TD + + 
Sbjct: 5   ISLGEGSGGRLTADLVASV-IKNFA----ACDGQKGGCEDCTFI-EGN-LAVTTDGFTVS 57

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P FFPGG++G LA+CG  ND+AV G  P++L+ G I+EEGLP   L  +V S A    A 
Sbjct: 58  PRFFPGGDMGHLAVCGATNDLAVRGVRPQWLTLGMIIEEGLPRAELLRLVRSAARQCEAL 117

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G  +  GDTKVV RGA + +F N   +G        G   L  GD L++S   G HGA I
Sbjct: 118 GATLAAGDTKVVPRGACEGVFFNVTALGRAVTPRPLGMNRLQPGDALILSTPPGRHGAVI 177

Query: 184 LNLREQLGLD-GELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
             LR   GLD G L SDCA L PL+  L  + G++ +RD TRGG+  V+ E+A A G G+
Sbjct: 178 AALR--YGLDRGGLESDCAALWPLLGPLLPLDGLRCMRDCTRGGLGTVLCEWAEATGLGM 235

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+ E  L + P+V  +C++LG D L  A+EG  +IA      E  LA L  HPLG+DAAL
Sbjct: 236 EIEEERLALHPSVAAICDILGFDPLYLASEGCALIACAPAETEIALARLRRHPLGRDAAL 295

Query: 303 IGEVVERKGVRLAGLYGVK------RTLDLPHAEPLPRIC 336
           IG V        AGL G+K      R +D+P  E LPRIC
Sbjct: 296 IGAVTAEH----AGLVGLKTRLGGSRIVDMPVGEILPRIC 331


>UniRef50_C1TK23 Hydrogenase expression/formation protein HypE n=1
           Tax=Dethiosulfovibrio peptidovorans DSM 11002
           RepID=C1TK23_9BACT
          Length = 328

 Score =  205 bits (522), Expect = 2e-51,   Method: Compositional matrix adjust.
 Identities = 133/340 (39%), Positives = 185/340 (54%), Gaps = 16/340 (4%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  + L  GSGG+   +LI   F   F        +   + DL          A + D +
Sbjct: 1   MGKLNLGQGSGGRLTSELIGK-FKAQF-------DDVNVQRDLEDCTMISPEWAVTIDGF 52

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+ FPGGNIGKLAICG  ND+AV G  P++++   I EEGL  E L     S A   
Sbjct: 53  TVSPMDFPGGNIGKLAICGGTNDLAVRGIEPKFVTLSVIAEEGLDEEELLRYGRSAASVC 112

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
               + +  GDTKVV +G VD LF+  A MG  P     G   +  GD L V+ ++G HG
Sbjct: 113 HGLEVKLAAGDTKVVPKGTVDGLFLTVASMGQ-PLGKPLGMDHIKPGDRLAVTTSIGRHG 171

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
           ATI ++R  L ++G L SDCA L PL++ L  +PGV+A+RD TRGG+   + E+A   G 
Sbjct: 172 ATIGSIRFDLNVEG-LSSDCAPLWPLVKPLAVLPGVRAMRDCTRGGLGTTLCEWAEGTGL 230

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           GIE+ E+++P+   V  VC++LG D L+ A EG  +IA   +  ++++  L +HP G  A
Sbjct: 231 GIEIDESSIPIDEEVSSVCDILGFDPLHLACEGCALIAYSPDDEDRIIEILRAHPSGIQA 290

Query: 301 ALIGEVVERK----GVRLAGLYGVKRTLDLPHAEPLPRIC 336
             IG VVE      G+R     G  R +D+P  E LPRIC
Sbjct: 291 TSIGTVVEGHPSMVGMRTKA--GGMRVVDMPVGELLPRIC 328


>UniRef50_A8A9S1 Hydrogenase expression/formation protein HypE n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8A9S1_IGNH4
          Length = 337

 Score =  191 bits (486), Expect = 2e-47,   Method: Compositional matrix adjust.
 Identities = 131/349 (37%), Positives = 194/349 (55%), Gaps = 28/349 (8%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAF-----ANPWLAEQEDQARLDLAQLVAEGDRLAFST 57
           ++ LA G GG+  ++ I +  +  F      +  L + ED A    A  + +   L  S 
Sbjct: 2   SVTLAVGGGGRETEEFIKNFILPLFKIRSLGSVGLDDLEDGA----AVPIGDNKYLVVSV 57

Query: 58  DSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMA 117
           DSY + P FFPGG+IGKLA  G+ NDVAV GA P+ L    I+EEG  +  LK ++ SM+
Sbjct: 58  DSYTVSPPFFPGGDIGKLAATGSLNDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMS 117

Query: 118 ETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLG 177
           E   +  +A++ GDTKV+ +G+VDK+ I+T G+G I             GD +LV+G +G
Sbjct: 118 EVTNSLNVALLGGDTKVMPKGSVDKIVISTVGIG-IAEGPLLTLDRGEPGDKVLVTGPVG 176

Query: 178 DHGATILNLREQLGLD-GELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEF 234
           DHGATIL L  Q GL    L SD   + P ++ LR+  G  +KA +D TRGG+   ++E 
Sbjct: 177 DHGATILAL--QFGLQVKTLKSDVRPVWPAVKALREALGEDLKAAKDPTRGGLAMALNEL 234

Query: 235 AAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSH 294
           A      + + EA +P++ AV+   E+LG++ L  A+EG+ V  V+ + AE+ L  L   
Sbjct: 235 AERSKTTVYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKA 294

Query: 295 PLGKDAALIGEVVERKGVRLAGLYGVKRT-------LDLPHAEPLPRIC 336
              ++AA+IGE+  RKG      Y + RT       L+ P  E +PRIC
Sbjct: 295 GF-EEAAIIGEL--RKG---KPGYVISRTPVGGLRLLEKPSGELVPRIC 337


>UniRef50_Q8NKU8 Membrane-bound NiFe hydrogenase n=1 Tax=Acidianus ambivalens
           RepID=Q8NKU8_ACIAM
          Length = 339

 Score =  185 bits (470), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 125/349 (35%), Positives = 186/349 (53%), Gaps = 27/349 (7%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAF--------ANPWLAEQEDQARLDLAQLVAEGDRL 53
           N IQ++HG+GG+  QQL+  LF                +   +D A L         + L
Sbjct: 4   NKIQISHGNGGKETQQLLQRLFFSRLPLELKRVKGGVGIDYPDDGAVLQ--------NNL 55

Query: 54  AFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVV 113
             +TDS+ ++P FFPGG+IG LA+ GT NDV + GA P  +    ++ EG P++ L+ + 
Sbjct: 56  VVATDSHTVNPYFFPGGDIGYLAVSGTLNDVIMMGAKPIAMLDSIVVSEGFPIDDLEKIT 115

Query: 114 TSMAETARAAGIAIVTGDTKVVQRGAV-DKLFINTAGMGAIPANIHWGAQTLTAGDVLLV 172
            SM E  +   I +V GD KV++  A+ + + INT G+G +          +  GD ++V
Sbjct: 116 GSMIELLKKYNIPLVGGDFKVIEETAMKNSIIINTVGLGVVETGSPI-VDAIKPGDKIIV 174

Query: 173 SGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVV 231
           +G +G HGA I  +  Q  +   L SD   L  L++      G V A RD TRGG+ A +
Sbjct: 175 TGPVGVHGAVIAAM--QYNISTNLKSDVRPLFELLEVFSKFKGYVHAARDPTRGGLAATL 232

Query: 232 HEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAAL 291
           +E+A   G  I + EA +PV   V+ + E+ GLD LN A+EG  V+AV+ N  + VL  L
Sbjct: 233 NEWAQLTGNVIVIEEAKVPVLEDVKAITEVTGLDPLNLASEGVGVLAVDSNVEDDVLETL 292

Query: 292 HSHPLGKDAALIGEVVE---RKGVRLAGL-YGVKRTLDLPHAEPLPRIC 336
            S  LG + A IG VVE    KG+ +A    G  + L++P  + +PRIC
Sbjct: 293 KS--LGFEPASIGYVVEPKSEKGIVVAKTAVGGAKILEMPTGDIVPRIC 339


>UniRef50_C5CEU2 Hydrogenase expression/formation protein HypE n=1 Tax=Kosmotoga
           olearia TBF 19.5.1 RepID=C5CEU2_KOSOT
          Length = 326

 Score =  185 bits (469), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 115/336 (34%), Positives = 184/336 (54%), Gaps = 18/336 (5%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L H SG +  + L +   +E      L   E+ +   L ++V        +TDS+ I 
Sbjct: 6   ITLHHNSGKKQFKLLKH---IEKLLGSTLVSTENDSGF-LEEVVD-----TVTTDSFTIS 56

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+FFPGG+IGKL++CG+ ND+ ++GA P+Y++   +LEEG     L  ++ S+ +     
Sbjct: 57  PVFFPGGDIGKLSVCGSINDLVMTGAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELDEN 116

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G+ I+ GDTKV++ GA+DK+ INT  +G +        + +   D+++++G +G HGA I
Sbjct: 117 GVKIIAGDTKVMEHGALDKIVINTTCLGEVLYE-KLCVKRIETNDLIIITGPIGLHGAAI 175

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
           +  R+   +D +  SDC VLT L+  ++ +  V A+RD TRGG+  +++EF+ +      
Sbjct: 176 MAERKGFQIDFQ--SDCRVLTKLLAVIKGLR-VHAMRDPTRGGLAQILNEFSHSTKRNFA 232

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + E  LP+   V+ V E+LG+D L  A EG  VI      A+ +L  L +   G D + I
Sbjct: 233 IYEDKLPIPGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNA--GFDPSTI 290

Query: 304 GEV---VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           G V   +ER  + L    G KR L +   E  PRIC
Sbjct: 291 GFVGGIIERPLLILKTRNGAKRVLPMLVEELTPRIC 326


>UniRef50_B1YBW5 Hydrogenase expression/formation protein HypE n=7 Tax=Archaea
           RepID=B1YBW5_THENV
          Length = 366

 Score =  182 bits (462), Expect = 2e-44,   Method: Compositional matrix adjust.
 Identities = 127/350 (36%), Positives = 188/350 (53%), Gaps = 25/350 (7%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDL-----AQLVAEGDRLAFSTD 58
           I+L+HGSGG    +++  LF+       L +      LD      A  +A+G  L  + D
Sbjct: 25  IKLSHGSGGVETSEIVEKLFLRRLPE-GLKKVAGGLGLDFPDDAAAIPMADGRYLVVTVD 83

Query: 59  SYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
           +Y ++P FFPGG+IG LA  G+ NDV + G  P  +    I EEGLP ETL  VV S   
Sbjct: 84  AYTVNPPFFPGGDIGMLAASGSINDVLMLGGRPLAMLDSIIAEEGLPYETLDRVVKSFLS 143

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD 178
              A G+A++ GD KV+ +G +DK+ I T G+G     I         GD ++VS  +GD
Sbjct: 144 VLEAEGVALIGGDFKVMPKGQLDKIVITTVGIGVADRII---VDKPRHGDKIVVSDFVGD 200

Query: 179 HGATILNLR-------EQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVV 231
           HGA IL L+       EQL L  ++     ++ PL++   +   + A RD TRGG+  V+
Sbjct: 201 HGAVILMLQMGDVDKPEQLQLKSDVKPLTKLMVPLVEKYGEY--IHAARDPTRGGLAMVL 258

Query: 232 HEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAAL 291
           +++A A G  I + E +LPV+P V     +LG+D L  A+EG  V+AV+   AE+V+  +
Sbjct: 259 NDWAKAGGGVIVVEEESLPVRPEVASYAGMLGIDPLYLASEGAAVLAVDPAVAEEVVKFM 318

Query: 292 HSHPLG-KDAALIGEVVE----RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
               LG ++A ++GE  E    R  V L  + G  R L+ P  + +PRIC
Sbjct: 319 RG--LGFQNARVVGEFREARQHRGYVLLKTVAGGLRILEPPRGDIVPRIC 366


>UniRef50_D2RDT5 Hydrogenase expression/formation protein HypE n=3
           Tax=Archaeoglobaceae RepID=D2RDT5_ARCPR
          Length = 344

 Score =  179 bits (454), Expect = 1e-43,   Method: Compositional matrix adjust.
 Identities = 119/352 (33%), Positives = 188/352 (53%), Gaps = 29/352 (8%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQL--VAEGDRLAFSTDSYV 61
           I+   G+GG+ M + +    +  F +  L E      + LA +   ++ D   F+TDSYV
Sbjct: 3   IRREDGAGGKYMAEFLKKHIISRFGDNRLGE------ISLADMDDSSDFDGYVFTTDSYV 56

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P  F GG+IG LA+CGTAND+AV GA P  +S   I++EG  +   + ++  +    +
Sbjct: 57  VSPPIFRGGSIGSLAVCGTANDLAVMGAKPYAMSLALIIQEGFKVSDFEKIMNDVERWVK 116

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMG----AIPANI-----------HWGAQT-LT 165
              + ++TGDTKVV      ++  NT+G+G    A+  NI           +W     L 
Sbjct: 117 ELDVKLITGDTKVVSANV--EIIANTSGIGIRNSALDHNISVVKEYRDYPYNWVRDCGLR 174

Query: 166 AGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRG 225
            GD ++VSG + DH   I+ L  +   D ++ SD   +   ++   ++ G+ A++D TRG
Sbjct: 175 EGDAIIVSGCVADHAVAIM-LSREFDFDIDVQSDVYPVWLFVKEALEVGGITAMKDPTRG 233

Query: 226 GVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAE 285
           G+   ++E A   G GI + E  +P++  V+G CE+LGLD L+ ANEGK+V+ V  + AE
Sbjct: 234 GLANALNELAEKSGVGIYIEEERIPIREEVKGFCEVLGLDPLSMANEGKVVMGVVEDMAE 293

Query: 286 QVLAALHSHPLGKDAALIGEVVE-RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            VL ALH     K A +IG      + V +    G K+ L  P A+P+PR+C
Sbjct: 294 DVLKALHKAG-QKYAEIIGYATSEFEEVVVETEIGTKKVLPPPTADPIPRVC 344


>UniRef50_B8D3R7 Hydrogenase expression/formation protein HypE n=1
           Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D3R7_DESK1
          Length = 349

 Score =  161 bits (408), Expect = 3e-38,   Method: Compositional matrix adjust.
 Identities = 114/351 (32%), Positives = 185/351 (52%), Gaps = 29/351 (8%)

Query: 4   IQLAHGSGGQAMQQLINSLFM-----EAFANPWLAEQEDQARLDLAQLVAEGDR-LAFST 57
           I   HG+GG     +I  L       + ++ P  A  +    LD    +  G+  + F++
Sbjct: 10  ITTLHGAGGIESWNIIEKLIRGRVPRDLWSTPGGAGLD---VLDDGSYIRIGESYIVFAS 66

Query: 58  DSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMA 117
           D+Y + PLFFPGGNIG+L   G  ND+ + GA P       ++EEG  +  L+ +V SM 
Sbjct: 67  DAYTVKPLFFPGGNIGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELEDIVDSMV 126

Query: 118 ETARAAGIAIVTGDTKVVQRGAVDKLFIN--TAGMGAIPANIHWGAQTLTAGDVLLVSGT 175
           +T     +A++ GD KV+ RG+VD + I+    G+   P  +     ++  GD ++V+  
Sbjct: 127 KTLVENNVALIGGDFKVMPRGSVDGVVISGFAIGVSGKPPVV----DSIKPGDKIIVTNY 182

Query: 176 LGDHGATIL-----NLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAV 230
           + +HG+TIL      L +  GL  ++      + P+I+  RD   + A RD TRGG+ A+
Sbjct: 183 IAEHGSTILAAQLDMLNDAPGLKSDVKPLVKTVLPVIEEYRDY--INAARDPTRGGLAAI 240

Query: 231 VHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAA 290
           ++E++ + G  I + +  +PV+  V    E+LG+D L  A+EG  V++V    A++V+ A
Sbjct: 241 LNEWSRSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEA 300

Query: 291 LHSHPLGKDAALIGEVVERKGVRLAG----LYGV-KRTLDLPHAEPLPRIC 336
           L  +  G++  +IGEVVE +   L G    L  V   T+  P A  LPRIC
Sbjct: 301 LRRN--GENPYIIGEVVEPRSRELRGRVVALTEVGGLTIIPPQAYNLPRIC 349


>UniRef50_A3DKG6 Hydrogenase expression/formation protein HypE n=1
           Tax=Staphylothermus marinus F1 RepID=A3DKG6_STAMF
          Length = 346

 Score =  157 bits (398), Expect = 4e-37,   Method: Compositional matrix adjust.
 Identities = 110/350 (31%), Positives = 179/350 (51%), Gaps = 27/350 (7%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDL----AQLVAEGDRLAFSTDS 59
           I   HGSGG    ++I  L +       L +  D   LD+    + +      +  STD+
Sbjct: 7   ITTVHGSGGFETLEIIEKLIVHRVPE-NLRKVLDGVGLDVLDDGSSMRIGNTHIVISTDN 65

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           + + PLFFPGG+IG LA+ G  ND+ + GA P     G I+EEG P + L  ++ SM + 
Sbjct: 66  FTVKPLFFPGGDIGHLAVSGVLNDLVMMGARPIAFMDGIIVEEGFPRDDLDRILESMIKL 125

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
            +   +A++ GD KV+ + ++D L I+  G+G     I      +  GD ++V+G + +H
Sbjct: 126 LKENNVALIGGDFKVMPKKSLDGLIISGTGIGLAEKPI---IDKIKPGDKIIVTGPIAEH 182

Query: 180 GATIL-----NLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEF 234
           GATIL      L +  GL  +       + P+++  RD   + A RD TRGG++ V++E+
Sbjct: 183 GATILAAQLGMLEQAQGLRSDTRPLVKTVLPILEKYRD--HIHAARDPTRGGLSIVLNEW 240

Query: 235 AAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSH 294
                  I ++ + +P++  VR   + LG+D L  A EG  +++V+   A++++  LH  
Sbjct: 241 VRGTKYTIVINRSTIPIRDEVRQFLDALGIDPLGVAGEGLAILSVDNEVADEIVEELHRR 300

Query: 295 --PLGKDAALIGEVVERKGVRLAGL------YGVKRTLDLPHAEPLPRIC 336
             P    A +IGEV+  +   LAG        G K  +  P+A  LPRIC
Sbjct: 301 GEPY---ATIIGEVIVPEEEYLAGRVIAITEVGGKVVVQ-PNALNLPRIC 346


>UniRef50_UPI0001B4B0DD hydrogenase expression/formation protein HypE n=1 Tax=Streptomyces
           sp. C RepID=UPI0001B4B0DD
          Length = 339

 Score =  153 bits (386), Expect = 9e-36,   Method: Compositional matrix adjust.
 Identities = 96/258 (37%), Positives = 153/258 (59%), Gaps = 4/258 (1%)

Query: 54  AFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVV 113
           A  + ++V+DP F+  G+IG++A+C T N++A +GA P  L+   ++E GLP+E L  + 
Sbjct: 54  ALVSGAHVVDPPFYGSGDIGRIAVCATVNELAAAGARPLALTLSAVVEAGLPLERLHRLA 113

Query: 114 TSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVS 173
            S+ + AR A + +   D +VV+ G  D+++++T G+GA         +    GD +L+S
Sbjct: 114 RSVRDAAREADVVVAGVDVRVVRAGEADQVYLHTTGIGAF-HGAPLDTRDARPGDRVLLS 172

Query: 174 GTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP---GVKALRDATRGGVNAV 230
             LG HGA IL++R  LG +  + S CA L  L++  R      G++A+R  TRGG+ A 
Sbjct: 173 APLGGHGAHILSVRRGLGFESLVPSGCAPLAGLLERARAAASGDGIRAVRTVTRGGLAAA 232

Query: 231 VHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAA 290
           +H +A   G  + + E+ALPV+   R   E + +D L+ ++E  L + V  +AA  VLAA
Sbjct: 233 LHAYARELGHTLRVEESALPVQYEARMALEAMAVDPLHASSESCLCLLVAPDAAPGVLAA 292

Query: 291 LHSHPLGKDAALIGEVVE 308
           L +HP G+ AA IG VVE
Sbjct: 293 LRTHPYGRFAAEIGTVVE 310


>UniRef50_B6YVE6 HypE n=9 Tax=Thermococcaceae RepID=B6YVE6_THEON
          Length = 330

 Score = 97.8 bits (242), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 77/285 (27%), Positives = 129/285 (45%), Gaps = 17/285 (5%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+      IG  A+   ANDVA  GA P++     +L E      L  ++  + E+A  
Sbjct: 52  DPITGAEEKIGFYAVHINANDVATFGAKPKWFLVSILLPENSDDALLVKIMDELHESASK 111

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
            G+AIV G T+V     +D+  +    +G +P      +     GD ++++   G  G  
Sbjct: 112 LGVAIVGGHTEVTP--GLDRPIVAGTMLGEVPKEKLVTSNGAKPGDAIILTKWAGLEGTA 169

Query: 183 IL------NLREQLGLDGELVSDCAVLTPLIQTLRDI-----PGVKALRDATRGGVNAVV 231
           I+       L +  G   E V     L  +I  + D       GV A+ D T GGV   +
Sbjct: 170 IIASERGKELEKAFG--KEFVEKAQSLIEMISVVEDALTANEIGVNAMHDPTEGGVANGL 227

Query: 232 HEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAAL 291
           HE A A   G  +    +P++     +CE   L+ L   + G L+IA  +  A+ +++AL
Sbjct: 228 HEMADAAKLGFRVYAERIPIRKETLKICEFYDLNPLALISSGALMIAAPKEKADSIISAL 287

Query: 292 HSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
                G +A++IGE +E K  R+    G ++ L+ P ++ L ++ 
Sbjct: 288 KRK--GINASVIGEFLEDKESRVMVDNGKEKPLERPESDELWKVV 330


>UniRef50_A1S0T2 AIR synthase related protein domain protein n=2 Tax=Archaea
           RepID=A1S0T2_THEPD
          Length = 335

 Score = 91.7 bits (226), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 78/256 (30%), Positives = 117/256 (45%), Gaps = 14/256 (5%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+     NIG L++  +ANDVA  G  PR+L    +L EG   + L  +   + + A  
Sbjct: 53  DPITGAVSNIGWLSVHVSANDVATRGVQPRWLVTVVLLPEGAGQDVLWDIAGQLRKAADE 112

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
            G  IV G T+      +D+  + T  MG               GD L+++   G  G  
Sbjct: 113 IGATIVGGHTEFTP--GLDRPILVTTAMGVGGKGEVLATSRARPGDALILTKGAGIEGTA 170

Query: 183 IL--NLREQLG--LDGELVSDCAVLTPLIQTLRDI------PGVKALRDATRGGVNAVVH 232
           IL   L ++L   +D E++         +  ++D        GV A+ D T GGV   + 
Sbjct: 171 ILATELYDELSRKVDREVLERAKSFIYEVSVVKDALTAVRAGGVHAMHDPTEGGVLGGLQ 230

Query: 233 EFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALH 292
           E A A   G+ + E  +PV+   + VC  LG+D L   + G L+IAVE + A  V+ AL 
Sbjct: 231 EMAIAANAGLVVEEEKIPVREETKAVCRALGVDPLRLISSGSLLIAVEGSRARDVVDALS 290

Query: 293 SHPLGKDAALIGEVVE 308
               G  AA+IG + E
Sbjct: 291 RE--GIPAAVIGRLTE 304


>UniRef50_B9KYQ7 Hydrogenase expression/formation n=2 Tax=Thermomicrobia (class)
           RepID=B9KYQ7_THERP
          Length = 343

 Score = 91.7 bits (226), Expect = 4e-17,   Method: Compositional matrix adjust.
 Identities = 76/259 (29%), Positives = 115/259 (44%), Gaps = 25/259 (9%)

Query: 52  RLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKA 111
           RL F +D     P+ F    IG  A+   ANDVA  GA PR+     +L EG      + 
Sbjct: 48  RLVFKSD-----PITFATEAIGWYALNVNANDVACLGARPRWFLATVLLPEGTTAHDAQV 102

Query: 112 VVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLL 171
           ++  +A  A   G+++V G T++     +D+  +    +G +          +  GD LL
Sbjct: 103 ILDDLARAAERLGVSVVGGHTEITV--GLDRPIVAGTMIGELTTEYVLSPARVRPGDALL 160

Query: 172 VSGTLGDHGATIL--NLREQLG--LDGELVSDCAVL------------TPLIQTLRDIPG 215
           +   +   G  +L    R+ L   LD +L++ C               T L++ L +   
Sbjct: 161 LVRGIAIEGTALLARECRQTLERMLDQDLLARCRRFLYEPGISIVPAATLLLERLGE--D 218

Query: 216 VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKL 275
           ++ L D T GG+   +HE A ACG G+ +SE A+ V P  R VC  LGLD L     G L
Sbjct: 219 LRYLHDPTEGGLATGLHEVAVACGTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGAL 278

Query: 276 VIAVERNAAEQVLAALHSH 294
           +  V   + E  L  L  H
Sbjct: 279 LAVVTPESVEHALDTLAQH 297


>UniRef50_B7R791 AIR synthase related protein, C-terminal domain n=2
           Tax=Thermoanaerobacteraceae RepID=B7R791_9THEO
          Length = 348

 Score = 87.4 bits (215), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 76/285 (26%), Positives = 133/285 (46%), Gaps = 29/285 (10%)

Query: 36  EDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLS 95
           ED + +D  + VA       STD     P+       G L++  + ND+A  GA P  + 
Sbjct: 51  EDSSIIDFGEYVA-----VLSTD-----PITAADKLSGFLSVIISCNDLAACGAEPIGIL 100

Query: 96  CGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
              +L EG   + LK ++  + + ++  GI ++ G T+V Q  AV+K  I+T  +G    
Sbjct: 101 TTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGGHTEVTQ--AVNKPVISTTAIGIARK 158

Query: 156 NIHWGAQTLTAGDVLLVSGTLGDHGATILN------LREQLGLD-----GELVSDCAVLT 204
             +  ++    GD ++V+  LG  G  IL       L +  G D        +++ +V+ 
Sbjct: 159 GKYITSKGAKIGDDVIVTKALGLEGTAILATDYEDLLIKHFGKDFVLKAQSFINEISVIE 218

Query: 205 PLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGL 264
             +   ++  G  A+ D T GGV    +E + A G GIE+ E  LP +   + +C+  GL
Sbjct: 219 EGLIASQN--GANAMHDITEGGVLGATYEISEASGLGIEIYEEKLPFRRETKEICKFFGL 276

Query: 265 DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
           + L   + G ++I  E     +++ AL     G  A +IG++V+ 
Sbjct: 277 NPLKLISSGSMLITAED--GNRIVKALSEK--GIQATIIGKIVKE 317


>UniRef50_UPI0001909C53 HypE protein n=1 Tax=Rhizobium etli IE4771 RepID=UPI0001909C53
          Length = 208

 Score = 87.4 bits (215), Expect = 7e-16,   Method: Compositional matrix adjust.
 Identities = 42/82 (51%), Positives = 55/82 (67%)

Query: 216 VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKL 275
           ++ +RD TRGG+ A ++E A+    G  + E A+P+KP V   CE LGLD LN ANEGKL
Sbjct: 20  IRLMRDPTRGGIAATLNEIASQSKVGFCIDEEAIPLKPEVAAACEFLGLDPLNVANEGKL 79

Query: 276 VIAVERNAAEQVLAALHSHPLG 297
           V  V R  AE VL+A+ +HPLG
Sbjct: 80  VAVVAREGAEAVLSAMRAHPLG 101


>UniRef50_A8MLK1 AIR synthase related protein domain protein n=3 Tax=Clostridiaceae
           RepID=A8MLK1_ALKOO
          Length = 330

 Score = 84.0 bits (206), Expect = 7e-15,   Method: Compositional matrix adjust.
 Identities = 70/285 (24%), Positives = 129/285 (45%), Gaps = 22/285 (7%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+     +IG LA+  + ND+A SG  P  +    +       E L  V++   + A +
Sbjct: 51  DPITGAAKDIGSLAVHISCNDIASSGVEPLGIMLTIMAPPHTTKEDLSLVMSEANKAAAS 110

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
             + I+ G T++    AV+++ I+   +G         ++     D + ++   G  G  
Sbjct: 111 VNVEIIGGHTEITD--AVNRMIISATAIGRQLKEKLVLSEGAKIDDAVFMTKYTGLEGTA 168

Query: 183 IL--NLREQLGLDGELVSDCAVLTPLIQTLRDIP-----------GVKALRDATRGGVNA 229
           I+  +L E+L    E +SD  + T   + L+DI            GV ++ D T GG+  
Sbjct: 169 IIARDLEEKLK---EKISDATIQTAQ-EFLKDISVVKEGITAGEVGVHSMHDVTEGGIFG 224

Query: 230 VVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLA 289
            + E   A G GIE+ E  +P++P    +C  L +D +   + G +V+ + ++  E ++ 
Sbjct: 225 ALWELGEASGIGIEIYEDQIPMRPETLEICHYLSIDPMRLISSGVMVMTIAQDKKEALME 284

Query: 290 ALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           A     L      IG +VE+  + ++   G+ R LD P  + L +
Sbjct: 285 AFKRENLI--LTEIGRMVEKDRIIISAAKGI-RALDPPDVDELYK 326


>UniRef50_B0R9W2 Hydrogenase expression/formation protein n=3 Tax=Halobacteriaceae
           RepID=B0R9W2_HALS3
          Length = 340

 Score = 82.4 bits (202), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 98/326 (30%), Positives = 140/326 (42%), Gaps = 48/326 (14%)

Query: 19  INSLFMEAFANPWLAEQED------QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI 72
           I++ F     +P L   +D      Q  +D   L   G RL  S D   ++P    G  I
Sbjct: 8   IDAEFFAQHLSPNLGADDDAVTVGPQYGVDFGVLSIGGQRLVVSADPVSVNP----GVGI 63

Query: 73  ---GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
              G+LA+    +DVAVSG  P +LS   +L      +T+ A+  +MA      G+++VT
Sbjct: 64  ERAGRLALHSVLSDVAVSGVPPSFLSITLVLPASARDDTIAALWDAMATECERLGVSVVT 123

Query: 130 GDTKVVQRGAVDKLFINTA---GMGAIPANIHWGAQTLTAGDVLLVSGT----------- 175
           G T    R  V   +I  A   G+G  PA I       TAGD +L++ +           
Sbjct: 124 GHTA---RQDVSFPWIGGATAMGVGD-PAEIV-RPDGATAGDTVLMTHSPGAEVAGLFAA 178

Query: 176 -LGDHGATILNLREQLGL---DGELVSD-CAVLTPLIQTLRDIPGVKALRDATRGGVNAV 230
             GDH     +  E+      D  +V D CA  +           V A+ DAT  G+   
Sbjct: 179 LFGDHLDVADDTVERADARLEDTTVVGDACAAASAP---------VTAMHDATECGIQGA 229

Query: 231 VHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAA 290
           + E A A G  I +S  A+PV   V  VC  LGLD    ++ G L++ V    A+  +AA
Sbjct: 230 LVELATAAGVSISVSSDAVPVPEDVSAVCADLGLDPWQVSSRGTLLVTVPEAHADTAMAA 289

Query: 291 LHSHPLGKDAALIGEVVERKGVRLAG 316
           L +       A IG V E  GV + G
Sbjct: 290 LDAR--NTPVAAIGTVSEGSGVTVDG 313


>UniRef50_B8I2N9 AIR synthase related protein domain protein n=6 Tax=Clostridium
           RepID=B8I2N9_CLOCE
          Length = 330

 Score = 80.5 bits (197), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 82/331 (24%), Positives = 150/331 (45%), Gaps = 35/331 (10%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAIC 78
           IN+   E    P + E       D A +  E D+ A    +   DP+   G N G+LA+ 
Sbjct: 19  INTFRKEVIMRPGIGE-------DCAAI--EFDKYACVMST---DPITAAGKNAGRLAVH 66

Query: 79  GTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRG 138
            + ND+A SG  P  L    +   G     L+ ++  + ETA    + I+ G T+V    
Sbjct: 67  ISCNDIASSGVEPLGLMVTILCPVGTTETELEHLMDQVCETAGQLNVEIIGGHTEVTP-- 124

Query: 139 AVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL--NLREQLGLDGEL 196
           AV+K+ ++T  +G    +    +     GD ++++ + G  G  I+  +  E+L    E+
Sbjct: 125 AVNKIILSTTCVGKSLKDKIISSSGAKPGDSVILTKSAGLEGTAIIAGDFEEELA---EV 181

Query: 197 VS--DCAVLTPLIQTLRDIP--------GVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
           ++  +      LI  +  +P        GV ++ D T GGV     E A A   G+ + +
Sbjct: 182 MNKNELQYAKSLINAISVVPEGVLAGRFGVTSMHDITEGGVLGAAWEIAEASSTGVTIKK 241

Query: 247 AALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
            ++PV+P  R +C+  G++ L   + G ++I  +    E ++  L  + +   A++IG +
Sbjct: 242 DSIPVEPVTRHICDHFGINPLRLISSGCMIITCKD--GEGLVRLLGENNI--KASIIGTI 297

Query: 307 VERKGVRL--AGLYGVKRTLDLPHAEPLPRI 335
            + K  RL  +   G    ++ P A+ L +I
Sbjct: 298 TQNKTGRLLISEKEGTSENIEAPGADELYKI 328


>UniRef50_C7NS45 AIR synthase related protein domain protein n=1 Tax=Halorhabdus
           utahensis DSM 12940 RepID=C7NS45_HALUD
          Length = 345

 Score = 79.7 bits (195), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 94/344 (27%), Positives = 137/344 (39%), Gaps = 61/344 (17%)

Query: 23  FMEAFANPWLAEQEDQARL------DLAQLVAEGDRLAFSTDSYVIDPLFF-PGGNIGKL 75
           F + +  P L    D  RL      D       G  LA +TD     P+F  P     + 
Sbjct: 13  FFDEYIYPRLGADRDDVRLQPQHGVDFGVADVGGQALAMATD-----PVFIVPAAGFERA 67

Query: 76  AICGTA---NDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           A        +DVAVSG  P YLS  F L   +  E  + V  +  + A   G +IVTG T
Sbjct: 68  AWFAFHILFSDVAVSGLDPAYLSVDFNLPPEITDEQFETVWETFDQEAAELGASIVTGHT 127

Query: 133 --------------KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD 178
                           V  G  D L       GA P +       +T G  +  +G L  
Sbjct: 128 GRYAGCNYPMVGGATTVATGDFDDLVTPD---GARPGD----RVIVTKGPAIEATGLLSV 180

Query: 179 HGATILNLREQLGLDGELVSD--------CAVLTPLIQTLRDIPG--VKALRDATRGGVN 228
           H  +++        DGE+ +D           ++P+ + +       V A+ DAT GGV 
Sbjct: 181 HFDSLM--------DGEVPADEIQAAKDRFYDMSPIQEAMVASAAGPVTAMHDATEGGVY 232

Query: 229 AVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVL 288
             + E A +   G E+    +PV+P V   C+   +D     +EG L+  V+ + A  VL
Sbjct: 233 GGLFEMARSADVGFEIERDRIPVQPGVEAACDFFDIDPWISISEGTLLATVDPDGASDVL 292

Query: 289 AALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           +AL S   G  AA  G VVE  G+ + G     + +D P  +P 
Sbjct: 293 SALKSE--GIPAADAGRVVEGSGLTVDG-----QAVDHPGKDPY 329


>UniRef50_Q2RKM3 AIR synthase related protein-like n=1 Tax=Moorella thermoacetica
           ATCC 39073 RepID=Q2RKM3_MOOTA
          Length = 528

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 79/270 (29%), Positives = 120/270 (44%), Gaps = 40/270 (14%)

Query: 63  DPLFFPG-----GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMA 117
           DP+F PG      + G + +   A+DVAV G  PR+++   +L  G P + +  +V S++
Sbjct: 50  DPIF-PGPTTSPDDFGWITVHIGASDVAVMGIKPRFMTYSLLLPPGTPEDYIAGLVRSIS 108

Query: 118 ETARAAGIAIVTGDTKVVQRGAVDKLF-INTAGMG---AIPANIHWGAQTLTA------- 166
             AR  GI IV G T       +  +  I   G G     PA    G   +         
Sbjct: 109 TYARELGITIVGGHTGFYGAVTIPTIGGITVWGRGREVVTPAGARVGDAVIITKGAAIEA 168

Query: 167 --------GDVLLVSGTLGDHGATILN-LREQLGLDGELVSDCAVLTPLIQTLRDIPGVK 217
                   G+ LL +G   D  A     LRE       +V++  +         ++ GV 
Sbjct: 169 AALVACELGEKLLAAGISPDLVARAKKRLREM-----SVVAEAGIAV-------EVGGVH 216

Query: 218 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVI 277
           A+ DAT GG+   + E A A G G+ +  A +PV   +R VC+ +GL+     +EG LV+
Sbjct: 217 AMHDATEGGLARGLWEVAEASGVGLRIERARVPVPADIRAVCDYIGLNPYEVISEGTLVL 276

Query: 278 AVERNAAEQVLAALHSHPLGKDAALIGEVV 307
                 A+ +LAA      G +AA+IG VV
Sbjct: 277 TCAPEKADAMLAAFKEA--GIEAAVIGRVV 304


>UniRef50_D1C5Z5 AIR synthase related protein domain protein n=7 Tax=Chloroflexi
           RepID=D1C5Z5_SPHTD
          Length = 359

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 84/302 (27%), Positives = 132/302 (43%), Gaps = 28/302 (9%)

Query: 50  GDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETL 109
           G  +A +TD + I P +         A+   A+D A SG  P Y      L   +  E L
Sbjct: 54  GRVMAVTTDPFFIVPQYG-WERAAWFAVHILASDAATSGLPPTYFVVDLNLPRNITSEGL 112

Query: 110 KAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLT-AGD 168
           +A+  ++  T +  G+AIVTG T   +    D   +  A + A+     +   T+   GD
Sbjct: 113 EALWHAVDATCKEIGMAIVTGHTA--RYDGTDYPMVGGAMVMAVGERDRYVTPTMARVGD 170

Query: 169 VLLVSG------------TLGD-----HGATILNLREQLGLDGELVSDCAVLTPLIQTLR 211
            ++V+             T  D     +G  I    E+      +V D   +T +   +R
Sbjct: 171 AVIVTKGAAIEATGLFGVTFPDRIAAAYGQEIARQAEETFYQMSVVKDA--MTAVEVGVR 228

Query: 212 DIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFAN 271
           D  GV A+ DAT GGV   ++E A A G G+ + + A+ V PA + VC+L G++     +
Sbjct: 229 DA-GVTAMHDATEGGVWGGLYEIAVASGVGMVVEQNAIVVSPAAQAVCDLFGMNPYAAIS 287

Query: 272 EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV-ERKGVRLAGLYGVKRTLDLPHAE 330
           EG L+I      A  VL  L     G  A  +GE+    +G+RL    G +  L+ P  +
Sbjct: 288 EGTLIITCRPEKAGAVLTRLED--AGIAATQVGEITPPEEGIRLV-RDGREEPLEHPRVD 344

Query: 331 PL 332
           P 
Sbjct: 345 PF 346


>UniRef50_B0KA39 AIR synthase related protein domain protein n=10 Tax=Clostridia
           RepID=B0KA39_THEP3
          Length = 331

 Score = 79.0 bits (193), Expect = 3e-13,   Method: Compositional matrix adjust.
 Identities = 71/283 (25%), Positives = 125/283 (44%), Gaps = 25/283 (8%)

Query: 36  EDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLS 95
           ED + +D  + VA       STD     P+       G L++  + ND+A  GA P  + 
Sbjct: 34  EDSSIIDFGEYVA-----VLSTD-----PITAAEKLSGFLSVIISCNDLASCGAKPIGIL 83

Query: 96  CGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
              +L EG     L  ++  + + A+   I ++ G T++     V+K  I+T  +G    
Sbjct: 84  STILLPEGSDESVLHNLMEEIDKAAKKLNIEVLGGHTEITT--TVNKPIISTTAIGMAKK 141

Query: 156 NIHWGAQTLTAGDVLLVSGTLGDHGATILNL-REQLGL---DGELVSDCAVLTPLIQTLR 211
             +   +    GD ++V+  LG  G  IL    E L L   D + +         I  + 
Sbjct: 142 GEYITTKGAKIGDDVIVTKALGLEGTAILATDYEDLLLKRYDKDFILKAQSFINEISVIE 201

Query: 212 D-----IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
           +       G  A+ D T GG+    +E A A G GIE+ E  LPV+P  + +C   G++ 
Sbjct: 202 EGLIAAQNGANAMHDITEGGILGAAYEIAEASGLGIEIYEEKLPVRPETKEICRFFGINP 261

Query: 267 LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
           L   + G ++I    +  ++++ +L     G  A +IG++++ 
Sbjct: 262 LKLISSGSMIITA--SDGDKIVKSLSEK--GIQATIIGKIIKE 300


>UniRef50_B0R2T1 Hydrogenase expression/formation protein n=2 Tax=Halobacterium
           salinarum RepID=B0R2T1_HALS3
          Length = 339

 Score = 77.0 bits (188), Expect = 8e-13,   Method: Compositional matrix adjust.
 Identities = 79/269 (29%), Positives = 117/269 (43%), Gaps = 28/269 (10%)

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           IC   +DVA+SG  P +L+    L      ET  A+       ARA G+++ TG T   +
Sbjct: 71  IC--VSDVALSGLSPAHLAVDLNLPPDTATETFDAIWEVFDREARALGVSLTTGHTGTYE 128

Query: 137 R------GAVDKLFINTAGMGAIPANIHWGAQTL-TAGDVLLVSGTLGDHGATILNLREQ 189
                  G    L +  A     P     G + + T G  +  +G LG      +   ++
Sbjct: 129 GCSFPTVGGATALAVGAAEDVVTPTGAQPGDRVVVTKGPAVETTGMLG------VLFGDR 182

Query: 190 LGLDGELVSDCAVLTPLIQTLRDIPG------VKALRDATRGGVNAVVHEFAAACGCGIE 243
           L +     +           +RD         V A+ DAT  G+   +HE AAA G G+ 
Sbjct: 183 LPISAAAAAAARDRFADATPVRDAATMAAAGEVTAMHDATERGLANGLHELAAASGVGLS 242

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           ++  A+PV P VR VCE  G+DA   ++EG ++ AV+  + + VL AL     G  AA +
Sbjct: 243 VARDAVPVLPGVRAVCEQFGMDAWAASSEGTVIAAVDPGSVDAVLGALGDE--GIPAADV 300

Query: 304 GEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           G V    GV + G       L  P A+PL
Sbjct: 301 GVVEAGSGVTVDG-----DPLAEPAADPL 324


>UniRef50_B8GHF5 AIR synthase related protein domain protein n=1
           Tax=Methanosphaerula palustris E1-9c RepID=B8GHF5_METPE
          Length = 345

 Score = 75.9 bits (185), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 82/296 (27%), Positives = 126/296 (42%), Gaps = 40/296 (13%)

Query: 63  DPLFF----PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
           DP+F     P    G   +   A+DVAV G  P+Y++   ++  G P +  + +V ++  
Sbjct: 55  DPIFAIPNQPYDLFGWHTVHIGASDVAVMGVKPQYMTYSLLMPPGTPDQDFRTIVDAIDL 114

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAG-----DVLLVS 173
            A+  GIAIV G T     G        T G   + A    G    +AG     DVLL  
Sbjct: 115 AAKDLGIAIVGGHT-----GYYPGFAAPTIGGITVFAVAEKGEYITSAGARPGDDVLLTK 169

Query: 174 GTLGDHGATILNLREQ----------------LGLDGELVSDCAVLTPLIQTLRDIPGVK 217
           G   +  A +  LRE                 L     +V+D A+        R+   V 
Sbjct: 170 GPAIETAALLSVLRENELKAKYPAWLVKAAQDLCWQMSVVADAALA-------REAGEVT 222

Query: 218 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVI 277
           A+ DAT GGV   + E AAA   G+ + EA +     VR VCE   LD L    EG L++
Sbjct: 223 AMHDATEGGVIGGLFEIAAASNTGMVIDEAQIIYPKEVRMVCEQFNLDPLASIAEGTLLL 282

Query: 278 AVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR-LAGLYGVKRTLDLPHAEPL 332
             + ++++ ++  L     G   ++IG+V +  G R +  + G    L +P  +P 
Sbjct: 283 TADPSSSDAIIDLLTRS--GIPVSVIGKVTDNPGERTIRRVDGTIEELHIPEQDPF 336


>UniRef50_Q97BE7 Hydrogenase expression formation protein HypE n=3 Tax=Thermoplasma
           RepID=Q97BE7_THEVO
          Length = 374

 Score = 75.5 bits (184), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 64/283 (22%), Positives = 129/283 (45%), Gaps = 20/283 (7%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPM 106
           +  G  +A +TD +  DP+F    +    A    A+D+  +G  P Y++    L   +  
Sbjct: 69  IGNGKVMAVTTDPFYFDPVF-GYEDSAWFAYHILASDITTAGVYPEYMTVDLNLPISISN 127

Query: 107 ETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLT- 165
           E +  +  ++ E A     +I+TG T   +        +  A M     +  +    +  
Sbjct: 128 EEIARMWKTVHEEAYKYKTSIITGHT--ARYANTGFPMVGGATMFGFTDDDKYVTTAMAR 185

Query: 166 AGDVLLVSGTLGDHGATIL------NLREQLGLDG-----ELVSDCAVLTPLIQTLR--D 212
            GD+++++ T G   A++L      ++++ LG D      EL    + +   IQ +    
Sbjct: 186 PGDIMIMTKTAGIEAASLLTRIFPNHVKKNLGEDKYRYGFELFRKLSTVDEAIQAIEFGT 245

Query: 213 IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANE 272
              + ++ DAT GG+   V+E A A G G+ + + A+ V   V+ +  L G+D L   +E
Sbjct: 246 RKAITSMHDATEGGLLGAVYEVAEASGNGVSIDKEAIHVDDYVKEIHSLFGIDPLRSISE 305

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER-KGVRL 314
           G L++ ++   A++ +  L     G D+ +IG++  + +G++ 
Sbjct: 306 GTLLMTIDPEYADEFMKRLTKS--GIDSYVIGKMTTKDEGIKF 346


>UniRef50_A7ALQ7 Putative uncharacterized protein n=1 Tax=Parabacteroides merdae
           ATCC 43184 RepID=A7ALQ7_9PORP
          Length = 93

 Score = 73.2 bits (178), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 40/90 (44%), Positives = 58/90 (64%), Gaps = 4/90 (4%)

Query: 249 LPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE 308
           LP+  AVRG  E+LGLD L+ ANEG +++ +     EQ LA + ++P GK+AA+IG  ++
Sbjct: 5   LPIPDAVRGASEILGLDPLHIANEGLVLVILPDEKTEQALAVMQNYPEGKNAAVIG-CIQ 63

Query: 309 RKG---VRLAGLYGVKRTLDLPHAEPLPRI 335
            KG   V++  LYG  R +D+   E LPRI
Sbjct: 64  EKGYALVKMKTLYGNYRIVDMLSDEQLPRI 93


>UniRef50_Q6KZH8 AIR Synthase n=1 Tax=Picrophilus torridus RepID=Q6KZH8_PICTO
          Length = 334

 Score = 72.8 bits (177), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 66/274 (24%), Positives = 128/274 (46%), Gaps = 34/274 (12%)

Query: 53  LAFSTDSYVIDPLFFPGGNIGKLAICGTA---NDVAVSGAIPRYLSCGFILEEGLPMETL 109
           LA +TD + IDP+F     + K A  G     +D+  SG    Y+S    L + +  +  
Sbjct: 45  LAVTTDPFYIDPVF----GLKKAAWFGFHILLSDIYTSGIPAMYMSIDLNLPQSMSDDEF 100

Query: 110 KAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTA--- 166
             + T + + ++   + +VTG T   +   V    I    +      + +G + +T    
Sbjct: 101 NEIWTVINDESKKYNVMVVTGHT--ARYAGVSYPMIGGVTL------MGYGDRYITTKNA 152

Query: 167 --GDVLLVSGTLGDHGATILN------LREQLGLD-----GELVSDCAVLTPLIQTLR-D 212
             GD+++++ T     + IL+      + + LG+D      +L      +   I ++   
Sbjct: 153 GDGDIIIMTKTCALEASCILSYTFPEYIEKHLGMDTLKKLNDLFYKMTCVNEEILSIDFG 212

Query: 213 IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANE 272
           +  + ++ DAT GG+   ++E   A G G+ +++  + +  +V  V +L  +D L   +E
Sbjct: 213 LDKITSMHDATEGGIINALYEIGKASGHGVIVNKNNINIDESVSRVTKLFNIDPLRSISE 272

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           G L+I V+RN A+++L  L S   G D+ +IGE+
Sbjct: 273 GTLLITVKRNFADELLLKLRSA--GIDSYIIGEL 304


>UniRef50_B9LTA0 AIR synthase related protein domain protein n=4
           Tax=Halobacteriaceae RepID=B9LTA0_HALLT
          Length = 330

 Score = 71.6 bits (174), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 82/284 (28%), Positives = 124/284 (43%), Gaps = 32/284 (11%)

Query: 36  EDQARLDLAQLVAEGDRLAFSTDSYVI---DPLFFPGGNIGKLAICGTANDVAVSGAIPR 92
           ED A +DLA            T+S ++   DPL      +G+LA+    NDVA SGA PR
Sbjct: 32  EDAAAIDLA-----------GTESTLVVAADPLSLAADAVGELAVHVACNDVAASGADPR 80

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAE-TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMG 151
           +L+    L +     T +  VT   + TAR  G+AIV G T+V+   ++++   +   +G
Sbjct: 81  WLTHTLFLPDD--DATRRRTVTQQVDATARDLGVAIVGGHTEVLP--SLERPLCSMTALG 136

Query: 152 AIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL--NLREQLGLDGELVSDCAVLTPLIQT 209
                +  G      GD LL++   G     IL  + RE     G   +        +  
Sbjct: 137 TTDRFVSSGGAE--PGDRLLLTKGAGIEATAILATDFREACAEAGVSAATLDAAAGFLDE 194

Query: 210 LRDIPGVKA-------LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELL 262
           +  +P   A       + D T GG+   + E A+A G  + +    +PV+P  R  C+ L
Sbjct: 195 VSVVPDAAAVRDAATAMHDPTEGGLLTALVETASASGTVLSVERDRVPVRPETRACCDAL 254

Query: 263 GLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           G+D L     G L+ AV     + V  AL +   G D   IGEV
Sbjct: 255 GVDPLATFGSGALLAAVPPERVDAVTDALAAA--GIDVGEIGEV 296


>UniRef50_A1HSU1 Thiamine-monophosphate kinase n=1 Tax=Thermosinus carboxydivorans
           Nor1 RepID=A1HSU1_9FIRM
          Length = 346

 Score = 71.2 bits (173), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 79/268 (29%), Positives = 119/268 (44%), Gaps = 26/268 (9%)

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G  AI    +D+A  G +PR+      L   +P+E +  +   M E  R   + IV G
Sbjct: 82  QLGYKAIAVNLSDIAAMGGVPRHAVISLALPRQIPVEFVVNLYQGMKEICREFRVNIVGG 141

Query: 131 DTKVVQRGAVDKLFINTAGMGAI-PANI--HWGAQTLTAGDVLLVSGTLGDH--GATILN 185
           DT     G    L IN A MG + P  +    GAQ    GD++ V+G LG    G  +L+
Sbjct: 142 DTVASPHG----LIINVAVMGEVEPTQLVRRSGAQV---GDMVAVTGVLGSSAAGLDLLS 194

Query: 186 LREQLGLDGELVSDCAVLTPLIQT----LRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
           L      D       A LTP  Q     L  + G  ++ D + G + +  HE A A   G
Sbjct: 195 LDNWAEYDFAWPLVTAHLTPRPQVKAGQLLGLYGATSMDDISDG-LASEAHEIAKASKVG 253

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEG----KLVIAVERNAAEQVLAALHSHPLG 297
           + +    +P+ P ++    +LG + L++A  G    +LV  + R      L AL +   G
Sbjct: 254 LRIEAKLVPLAPELKQAAAMLGKEPLDYALYGGEDYQLVFTIGREK----LQALSAVDFG 309

Query: 298 KDAALIGEVVE-RKGVRLAGLYGVKRTL 324
               +IGEV E   GV+L    GV++ L
Sbjct: 310 VPLTVIGEVTEAADGVKLVMDDGVEQEL 337


>UniRef50_D1VUU5 Hydrogenase maturation factor n=1 Tax=Peptoniphilus lacrimalis
           315-B RepID=D1VUU5_9FIRM
          Length = 325

 Score = 70.5 bits (171), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 75/303 (24%), Positives = 127/303 (41%), Gaps = 20/303 (6%)

Query: 41  LDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFIL 100
           +D A L   GD +  S     +DP+     N+G LAI  + NDV+  GA P  +    +L
Sbjct: 34  IDTAVLDFNGDLIVTS-----VDPITGANKNLGYLAINISVNDVSCQGADPVGVLISILL 88

Query: 101 EEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWG 160
                +E L  ++       R   + I+ G T+V    AV+K+ + T  +  +  N    
Sbjct: 89  PAESKLEDLNKIMEDADRACRQNNLEIIGGHTEVTD--AVNKIVLTTTVIARVNKNKMPK 146

Query: 161 AQTLTAGDVLLVSGTLGDHGATILNLRE---QLGLDGELVSDCAVLTPLIQTLRDIP--- 214
             ++  GDV+ VS  +G  G +I+ L E   +   + EL  +   +  L   LR+     
Sbjct: 147 ISSIKVGDVIAVSKDIGLEGTSII-LEEKGNEFLSEDELRKESIDIKDL-SVLREAKIAV 204

Query: 215 --GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANE 272
              VK + D T GG+   + E + A G GIE+    +PVK   + +     ++     + 
Sbjct: 205 DFNVKYMHDVTEGGIYGALWECSEAIGKGIEVDNIKIPVKDVTKKIGSHYNINIYGLISS 264

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           G +++   +   +    A     +      IGEV E     L    G K  +  P ++ L
Sbjct: 265 GSMLMVFNKEDFKAYKKACFEKNIK--ITQIGEVTEENKKILID-NGKKIEIPEPASDEL 321

Query: 333 PRI 335
            +I
Sbjct: 322 YKI 324


>UniRef50_C9L525 Hydrogenase maturation factor n=1 Tax=Blautia hansenii DSM 20583
           RepID=C9L525_RUMHA
          Length = 344

 Score = 70.5 bits (171), Expect = 9e-11,   Method: Compositional matrix adjust.
 Identities = 70/282 (24%), Positives = 125/282 (44%), Gaps = 16/282 (5%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+     +IG  ++  TAND+A SGA P  +    +L        LK ++  + +T + 
Sbjct: 68  DPITGTTKDIGGHSVHITANDLAASGAEPVGIMLTMLLTPDTEEAQLKEIMQDVEKTCKE 127

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
             + ++ G T+V     V +  I+  G+G +         ++  GD ++V+  +G  G +
Sbjct: 128 LNMEVLGGHTEVTD--VVKQTLISLTGVGKMKKENVLTTASVKPGDDIVVTKWIGLEGTS 185

Query: 183 IL-NLREQLGLDGELVSDCAVLTPLIQTLRDIP--------GVKALRDATRGGVNAVVHE 233
           I    +E L L+              Q L  IP        GV A+ D T GGV   + E
Sbjct: 186 IAAKEKESLLLEHFAPPFVETAKKFDQYLSVIPEAKIAAEWGVSAMHDITEGGVFGALWE 245

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS 293
             +  G G+++    +P++     VCE+LGL+     + G ++IA +      ++  L  
Sbjct: 246 MGSGSGVGLDIDLKEIPIRQETVEVCEVLGLNPYILMSSGSMMIAAKDGYG--LVRKLKQ 303

Query: 294 HPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
              G +AA++G+  +    R+       R LD P ++ L +I
Sbjct: 304 A--GIEAAVVGKATDGND-RILRNGEDTRYLDKPQSDELYKI 342


>UniRef50_C0CMS4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C0CMS4_9FIRM
          Length = 339

 Score = 70.1 bits (170), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 75/289 (25%), Positives = 127/289 (43%), Gaps = 30/289 (10%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+     +IG   I  TAND+A +GA P  +    +L      + L+ +V  M +T  A
Sbjct: 52  DPITGTVKDIGSHCIYITANDLAAAGAEPVAVMVTALLPPETEEKDLRGIVEDMEKTCAA 111

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
             + ++ G T+V     V +  ++  G+G + A      + L AG  L+V+  +G  G +
Sbjct: 112 LDMEVIGGHTEVTD--TVKQPLLSVTGVGKMKAGEALYEKKLKAGQDLVVTKWIGLEGTS 169

Query: 183 ILNLREQLGLDGELVSDCAVLTP--LIQTLRDIP--------GVKALRDATRGGVNAVVH 232
           I+  +E+     E+ ++  V T     Q L  +P        GV  + D T GGV   + 
Sbjct: 170 IVA-KERAQKLREVFAESFVRTAQNFDQYLSVLPESRIAMEHGVSVMHDITEGGVFGALW 228

Query: 233 EFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALH 292
           E A     G+++    +P++     VCE  GL+     + G ++I  E+   E ++  L 
Sbjct: 229 ELAQGADVGLDVDLKKIPIRQETVEVCEQFGLNPYLLMSSGAMLIGTEQ--GEILVRKLQ 286

Query: 293 SHPLGKDAALIGEVVE------RKGVRLAGLYGVKRTLDLPHAEPLPRI 335
               G    +IG+ VE      R G  +       R LD P ++ L +I
Sbjct: 287 EA--GIPGTVIGQAVEGSSRILRNGEEI-------RYLDRPQSDELYKI 326


>UniRef50_C6A3P3 Hydrogenase expression/formation protein HypE n=2 Tax=Thermococcus
           RepID=C6A3P3_THESM
          Length = 349

 Score = 69.7 bits (169), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 65/269 (24%), Positives = 115/269 (42%), Gaps = 16/269 (5%)

Query: 53  LAFSTDSYVI---DPLF-FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMET 108
           L +   +Y++   DP+   P  + G       ++DVAV GAIP++L    +L  G   E 
Sbjct: 61  LEYDEKNYLVIATDPILGVPKEHFGFFTYHFASSDVAVFGAIPKWLIVNLLLPNGTTEED 120

Query: 109 LKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGD 168
           L +V+  + E  +  G +I+ G T V            T  +G +  +           D
Sbjct: 121 LNSVMRELNEECKKYGTSIIGGHTGVYSTTRSFTA--TTTAIGLVKKDELKLPLAKPGDD 178

Query: 169 VLLVSGTLGDH--GATILNLRE-QLGLDGELVSDCAVLTPLIQTLRDI----PGVKALRD 221
           +++  G   +   GA      E +  L    +S    +  L   ++D        + + D
Sbjct: 179 IIITKGIAIEFAVGAAWFRTEELKKILSPSQISSLREMYTLETVVKDALLAKKFARGMHD 238

Query: 222 ATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVER 281
            T GG+   +HE A     G E+    L + P V+ V +  G++ L  ++ G L+I   +
Sbjct: 239 VTEGGLTT-LHEIADNSEVGFEVYYEKLHMPPLVKKVVKFYGVNPLTVSSTGTLIIISPQ 297

Query: 282 NAAEQVLAALHSHPLGKDAALIGEVVERK 310
               +++ ALHSH  G +A+ +G+  E K
Sbjct: 298 ENTSKLIKALHSH--GINASTVGKFTEEK 324


>UniRef50_C7G8J7 Hydrogenase maturation factor n=4 Tax=Clostridiales
           RepID=C7G8J7_9FIRM
          Length = 331

 Score = 69.3 bits (168), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 64/245 (26%), Positives = 109/245 (44%), Gaps = 24/245 (9%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPM 106
           +AE + L  STD     P+     +IG LAI  TAND+A +GA P     G +L   LP 
Sbjct: 45  LAEDETLVMSTD-----PITGTAQDIGTLAIQITANDLASAGAEP----VGVLLTVLLPP 95

Query: 107 ETLKAVVTSMAETARAA----GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQ 162
           E  +  +  M +   AA    G+ ++ G T++     V++  I+  G+G +         
Sbjct: 96  EIEEPDLREMMQQVEAACAKAGVQVMGGHTEIT--AVVNQPVISVCGVGKVKDGCLISTG 153

Query: 163 TLTAGDVLLVSGTLGDHGATILNLREQLGL----DGELVSDCAVLTPLIQTLRDI----- 213
               G  +LV+  +G  G +I+   ++  L        + +   L   +  L +      
Sbjct: 154 GAKPGMDILVTKWIGIEGTSIIAKEKEKDLLTRFSAPFIENAKKLDVYLSVLSEAAVAVR 213

Query: 214 PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEG 273
            GV A+ D T GG+   + E A A G G+E+    +PV+     +CE  G++     + G
Sbjct: 214 SGVSAMHDVTEGGIFGALWEMAEASGVGLEIDLKKIPVRQETIEICEFFGINPYELISSG 273

Query: 274 KLVIA 278
            +++A
Sbjct: 274 SMLMA 278


>UniRef50_D2RZQ8 AIR synthase related protein domain protein n=1 Tax=Haloterrigena
           turkmenica DSM 5511 RepID=D2RZQ8_9EURY
          Length = 346

 Score = 66.2 bits (160), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 67/244 (27%), Positives = 104/244 (42%), Gaps = 23/244 (9%)

Query: 83  DVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQR----- 137
           DVAVSG  P +LS  F L E +  +    V  ++ E     G+A+VTG T          
Sbjct: 76  DVAVSGIPPSHLSICFTLPETMTDDEFATVWKTIHEECVDLGVAVVTGHTARYSDPSHPW 135

Query: 138 -GAVDKLFINTAGMGAIPANIHWGAQTL-TAGDVLLVSGTLGDHGATILNLREQLGLDGE 195
            GA   + +        P     G + L T G  +   G L    +T+   + +  L G+
Sbjct: 136 VGAATAMAVGDPDEIVRPDGARPGDRLLLTTGPAVESVGLL----STLFADQLEAALPGD 191

Query: 196 LVSDCAVLTPLIQTLRDIPG------VKALRDATRGGVNAVVHEFAAACGCGIELSEAAL 249
           ++ D       +  +RD         V A+ D T GG+   ++E A   G    +   A+
Sbjct: 192 VIDDAQDRLEEVYCVRDALAAAAAGPVTAMHDVTEGGLAGALNEMADGAGARFSVDRDAV 251

Query: 250 PVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA--ALIGEVV 307
           P++P V+ VC+ L +D     + G L++AV     + V+AAL      +D   A IG V 
Sbjct: 252 PMRPGVQEVCDHLEIDPWAATSSGSLLLAVAPEGVDDVVAALED----RDTVVAEIGRVE 307

Query: 308 ERKG 311
           E  G
Sbjct: 308 EPSG 311


>UniRef50_A3DLS7 AIR synthase related protein domain protein n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DLS7_STAMF
          Length = 355

 Score = 65.9 bits (159), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 62/242 (25%), Positives = 104/242 (42%), Gaps = 28/242 (11%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+      IG LA+   AND+AV GA PR+     +L    P+E ++++   +    R+
Sbjct: 70  DPITAATRRIGWLAVHIVANDIAVRGATPRWFLPVILLPPKYPVEQIESIFEDIGLATRS 129

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
            G  ++ G T+      + +  I+   +G     +    +    GD + + G +G  GA+
Sbjct: 130 LGATVIGGHTEFTP--GIPRPIISMTAIGYSMDKVVL-TRNARPGDKIFIIGRVGGEGAS 186

Query: 183 I-------LNLREQLGLD----------GELVSDCAVLTPLIQTLRDIPGVKALRDATRG 225
           +       L LR+ +  D          G  V D A+L      +RD   V ++ D T G
Sbjct: 187 VIAWDFEDLLLRKGISRDIIAKAKEYFTGISVVDKALL------IRDY--VNSMHDPTEG 238

Query: 226 GVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAE 285
           G+   + E A A    I L    + + P V+ +   L LD L   + G L+ +V +    
Sbjct: 239 GLLQGLREVAKASNTRIILDADKIILDPVVKEITSALKLDPLKILSSGVLIASVPKENTR 298

Query: 286 QV 287
           QV
Sbjct: 299 QV 300


>UniRef50_B6YUV4 HypE n=3 Tax=Thermococcus RepID=B6YUV4_THEON
          Length = 332

 Score = 65.9 bits (159), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 71/274 (25%), Positives = 111/274 (40%), Gaps = 26/274 (9%)

Query: 53  LAFSTDSYVI---DP-LFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMET 108
           L +  + Y+I   DP L  P    G       A+DVAV GA PR+L    +   G     
Sbjct: 41  LEYDHEHYLIVATDPTLGVPEETFGFFTYHFAASDVAVFGARPRWLIVDLLFPPGTERSF 100

Query: 109 LKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGD 168
           L+ ++ S+    R  G +I+ G T       + +    T  MG +  +          GD
Sbjct: 101 LENIMRSLNTECRKYGSSIIGGHTGAYP--TIAEPTSTTTAMGLVRKD-ELKLPLAEPGD 157

Query: 169 VLLVSGTLGDHGAT------------ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGV 216
            ++V+  +G   A              L  +E   L      + A+   LI      P V
Sbjct: 158 KIIVTAKIGLEFAVSAAYFREEELRKFLTFKEIERLKRLFTFETALPDALIAR----PFV 213

Query: 217 KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLV 276
           + + DAT GG+ A +HE A   G G  +    L + P VR V E  GL+  + ++ G L+
Sbjct: 214 RGMHDATEGGLTA-LHEIAENSGVGFRVYADRLYLDPLVRKVLEFYGLEPWSVSSTGTLI 272

Query: 277 IAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
                  A+ ++  L+ +  G  A  +GE  E K
Sbjct: 273 AITPPEKADALITELNKN--GIMAFELGEFTEEK 304


>UniRef50_C7NRE1 AIR synthase related protein domain protein n=4
           Tax=Halobacteriaceae RepID=C7NRE1_HALUD
          Length = 340

 Score = 65.5 bits (158), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 87/313 (27%), Positives = 134/313 (42%), Gaps = 36/313 (11%)

Query: 19  INSLFMEAFANPWL-AEQED-----QARLDLAQLVAEGDRLAFSTDSYVIDP-LFFPGGN 71
           I++   ++   P L A++ED     Q  +D   L  E   +  +TD   I P L F    
Sbjct: 7   IDTETFDSVIAPHLGADREDVTIGPQHGVDFGVLSVEESAVVVATDPISILPELGFE--R 64

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
            G++A+     DVAVSG  P +++    L   +  E L      MA+ A   G++IV+G 
Sbjct: 65  AGRVALDIVLTDVAVSGIAPTHITVSLSLPPEMTDEELGQTWRGMADHAENLGVSIVSGH 124

Query: 132 TKVVQRGAVDKLFINTA---GMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL-R 187
           T   +   ++  ++  A   G+G  PA+I           V+L +G   +       L  
Sbjct: 125 TARYE--GIEYSWVGGATALGVGD-PADIVRPDGANPGDAVVLATGPGAETAGLFATLFP 181

Query: 188 EQLGLDGELVSDCAVLTPLIQTLRDIPGV------------KALRDATRGGVNAVVHEFA 235
           E L L  + V+         + + DI GV             A+ D T GGV   + E A
Sbjct: 182 EALELPAKTVATAQ------ECVGDILGVADATTAAAAGELTAIHDTTEGGVIGGLTEMA 235

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
              G   ++     PV+P V  VC+ +G+D     + G L+I      AE V+ AL +H 
Sbjct: 236 TGAGVTFDVRRDPAPVQPGVAAVCDAIGVDPWTVTSAGSLLITAPPATAESVVEALEAH- 294

Query: 296 LGKDAALIGEVVE 308
            G  AA+IG V E
Sbjct: 295 -GTPAAVIGSVEE 306


>UniRef50_A4WH94 AIR synthase related protein domain protein n=5
           Tax=Thermoproteaceae RepID=A4WH94_PYRAR
          Length = 335

 Score = 63.9 bits (154), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 71/253 (28%), Positives = 109/253 (43%), Gaps = 15/253 (5%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+      +G LA+    NDVAV G  P +LS   +L  G   + L A+   M   AR 
Sbjct: 51  DPITGSVNLLGSLAVYVPTNDVAVRGVEPMWLSVALLLPPGASDDLLDAITRQMDMAARR 110

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
            G+ IV G T+V          +   G+G+   +   GA+    GDV++++ + G   A+
Sbjct: 111 LGVTIVGGHTEVTTAVTRPVAVVTAMGVGSRFVSTS-GAK---PGDVVVMTKSAGQETAS 166

Query: 183 IL--NLREQ---LGLDGELVSDCAVLTPLIQTLRDIPGV----KALRDATRGGVNAVVHE 233
           IL  +  E+    G+  E +     L   I   R+   +     ++ D T GGV   + E
Sbjct: 167 ILASDFAEEALRRGVPAEALERARGLIAEISVAREALALADLATSMHDPTEGGVANGLAE 226

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS 293
            A A    I++    + V   V  +C    +D L   + G L+  V R    + L  L  
Sbjct: 227 IAYASKVSIDVRRKDVVVYREVEALCRAFRIDPLETLSSGVLLATVPRGRLGEALERLQK 286

Query: 294 HPLGKDAALIGEV 306
             LG   A+IGEV
Sbjct: 287 --LGVPHAVIGEV 297


>UniRef50_A4XL04 AIR synthase related protein domain protein n=2 Tax=Clostridia
           RepID=A4XL04_CALS8
          Length = 325

 Score = 63.5 bits (153), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 57/261 (21%), Positives = 113/261 (43%), Gaps = 14/261 (5%)

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           +DP+   G   G L++    ND+A +GA P  + C  ++      E    ++  + E  +
Sbjct: 49  MDPITAAGSMSGYLSVVVVCNDLAAAGAEPIGVLCTILMPPESSQEEFIQILRDIKEACK 108

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
              I ++ G ++V     V K  I + G G +  ++         GD ++++ TLG  G 
Sbjct: 109 RFNIQLLGGHSEV--SPIVTKPLIVSTGFGKVERDMLISTSKAKVGDKIIITKTLGIEGT 166

Query: 182 TIL--NLREQLG--LDGELVSDCA----VLTPLIQTLRDIPGVKALRDATRGGVNAVVHE 233
            IL    +E+L   L  E VS+       L+ + + L       ++ D T GG+   ++E
Sbjct: 167 FILYNEKKEKLKTFLTPEEVSEIENYINKLSVVEEGLVARKYASSMHDITEGGLFGAIYE 226

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS 293
              A G G  + E  + +  +V+ +     L+     + G ++I  ++    +++  L  
Sbjct: 227 VCKASGKGARIYEEKIVLSSSVKKISSFYNLNPYKLISSGSMLITTDKE--NELICELKE 284

Query: 294 HPLGKDAALIGEVVERKGVRL 314
              G D  ++GE++E   +  
Sbjct: 285 K--GIDCYVVGEIIEEPKIEF 303


>UniRef50_C3N301 AIR synthase related protein domain protein n=9 Tax=Sulfolobus
           RepID=C3N301_SULIA
          Length = 402

 Score = 62.8 bits (151), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 78/312 (25%), Positives = 129/312 (41%), Gaps = 28/312 (8%)

Query: 37  DQARLDLAQLVAEGDRLAFSTDSYVIDPLF-FPGGNIGKLAICGTANDVAVSGAIPRYLS 95
           D A +DL     +G  L   TD   I P F F        A+   A+DV  SG  P+Y  
Sbjct: 96  DTAAIDLQ----DGRILVVKTDPVFIVPQFGFKKA--AWFAVHILASDVMTSGIPPQYAV 149

Query: 96  CGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ------RGAVDKLFINTAG 149
               L   +  +  + +   + E  +   + +V G T V +       G      I    
Sbjct: 150 IDVNLPPKIKDDEFEEMWIGIHEALKEIEVMVVGGHTGVYEGTDYPMVGGFTMFGIGEKE 209

Query: 150 MGAIPANIHWG-AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQ 208
              +P+ +  G +  +T G  +  +G L +        R    LD E  ++   +   + 
Sbjct: 210 KLGMPSKVRVGDSVIMTKGPAIEATGLLTNLYPEYFKQR----LDKETFNEAYNIYWKMS 265

Query: 209 TLRD-----IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLG 263
             +D       G+  + DAT GGV   + E A A G G+ + E  L +  AVR V  L+ 
Sbjct: 266 CWKDGLIASRIGIHLMHDATEGGVFGALTEVARASGKGMNVYEDKLFINSAVREVTRLVN 325

Query: 264 LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG-VRLAGLYGVKR 322
           +D     +EG ++I  ++   + V  AL     G +A +IGE+V++ G V+L    G + 
Sbjct: 326 IDPWISISEGTMIIVTDK--GKDVREALIKE--GIEAEIIGEIVDQSGDVKLVKKDGSRV 381

Query: 323 TLDLPHAEPLPR 334
            ++ P  +P  R
Sbjct: 382 KIEHPLEDPFWR 393


>UniRef50_A8ZNV6 Hydrogenase expression/formation protein HypE n=2 Tax=Bacteria
           RepID=A8ZNV6_ACAM1
          Length = 339

 Score = 62.4 bits (150), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 56/244 (22%), Positives = 101/244 (41%), Gaps = 15/244 (6%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA-R 121
           DP+ F   +IG   +   AND+A +GA PR+L    +L E     TL   +     TA +
Sbjct: 55  DPITFVTDDIGWYVVQINANDIATTGATPRWLMATILLPEQRTTATLAERIHQQIYTACQ 114

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
              ++++ G T++     +D+  +    +G +  +     +    GD +L++ ++     
Sbjct: 115 EINVSLIGGHTEITY--GIDRPIVVGTLIGEVARDSLITPRGAKPGDRILLTKSVPIEAT 172

Query: 182 TILNLREQLGLDGELVSD------CAVLTPLIQTLRDIP------GVKALRDATRGGVNA 229
            IL       +   L SD        +  P I  LRD         V A+ D T GG+ A
Sbjct: 173 AILAREYSEQISQALTSDELTQARGYLYKPGISVLRDAQLANQAGQVSAMHDPTEGGLLA 232

Query: 230 VVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLA 289
            + E A A  C + +    +P+      +C +  +D L     G L++   +  A  +  
Sbjct: 233 ALWELAQASNCQLVIDLEKVPISDLSAHICRVFKIDPLAAIASGALLLTAPQRDAPSICR 292

Query: 290 ALHS 293
            L++
Sbjct: 293 TLNT 296


>UniRef50_B5Y6B6 Hydrogenase expression/formation protein HypE n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y6B6_COPPD
          Length = 339

 Score = 62.0 bits (149), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 77/283 (27%), Positives = 119/283 (42%), Gaps = 34/283 (12%)

Query: 50  GDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETL 109
           GD L  S     +DP+      IG LA+    ND+A SG  PR++    +L      E L
Sbjct: 42  GDDLLLSH----VDPIVGAVNGIGWLAVHVACNDIAASGIKPRWVQLLVMLPSLDQPEEL 97

Query: 110 KAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI--HWGAQTLTAG 167
           K +++  A  A +  + I+ G T+    G    L   TA   A    +    GA+    G
Sbjct: 98  KQIMSDAARAADSLNVTIIGGHTEA-SNGLRRPLVAATALAPACGKRVVRTSGAK---PG 153

Query: 168 DVLLVSGTLGDHGATIL----------------NLREQLGLDGELVSDCAVLTPLIQTLR 211
           D++ V+  +G  G  IL                +L E L    +L+S  +V++  ++ L 
Sbjct: 154 DIIYVTRGVGLEGTGILASDFAVEARKRGLTDQDLNEAL----KLLSSVSVVSEALK-LA 208

Query: 212 DIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFAN 271
           D+ G  A+ D TRGG+   + E A+  G  +E+  + +PV   V+        D L   +
Sbjct: 209 DL-GATAMHDVTRGGILETLLEIASCSGVCMEVDRSRIPVPEVVKRFANAFEFDPLKMIS 267

Query: 272 EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
            G LV  +     E   A   + P       IG V E +GV L
Sbjct: 268 SGTLVATLPPEMCETAEALFENQPC--KLFRIGVVTEGRGVLL 308


>UniRef50_Q9YA95 Putative hydrogenase expression/formation protein HypE n=1
           Tax=Aeropyrum pernix RepID=Q9YA95_AERPE
          Length = 345

 Score = 62.0 bits (149), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 79/284 (27%), Positives = 120/284 (42%), Gaps = 20/284 (7%)

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           +DP+   G   G LA+   AND+AV+GA PR+     ++  G   ++L +++      A 
Sbjct: 56  LDPITEAGALAGWLAVHVAANDIAVTGARPRWEMLAVLMPPGSSEDSLASLLGDAVRAAE 115

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
             G+ IV G T+      V +  I  A  G               GD++L        G 
Sbjct: 116 EIGVEIVGGHTEAAP--GVPRPIIVAAAAGITCGGCTTPTSAARPGDLVLQVKPAAIEGT 173

Query: 182 TILN------LREQ-LGLDG-----ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNA 229
            I+       LR + +G D       L S  +++   I+ L +   V+A+ D T GGV  
Sbjct: 174 AIIATDFADMLRSRGVGEDAIAGARMLASRVSIVEEAIE-LAEAGVVRAMHDPTEGGVLG 232

Query: 230 VVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLA 289
            + E A A    IE+ E  + V  A R V   LG+D L   + G L+  V  + A +   
Sbjct: 233 GLVEMALASRTVIEVEEDKIIVGEATRIVASALGIDPLRLISSGTLLATVPPDKAGEARY 292

Query: 290 ALHSHPLGKDAALIGEVVERKG---VRLAGLYGVKRTLDLPHAE 330
            L    LG + + IG V  R G   +RL+    VK   + P  E
Sbjct: 293 VLEE--LGVEYSFIGRVAARSGEPALRLSSRGRVKTFREPPMDE 334


>UniRef50_C7H113 Hydrogenase maturation factor n=1 Tax=Eubacterium saphenum ATCC
           49989 RepID=C7H113_9FIRM
          Length = 347

 Score = 62.0 bits (149), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 59/258 (22%), Positives = 110/258 (42%), Gaps = 15/258 (5%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+      IGKLA+  + ND+A +G  P  L+   +L +G   E ++ ++    E A  
Sbjct: 60  DPITATPNEIGKLAVYISCNDIASNGIEPFALTMSVLLPKGTTEEEVELIMKQAGEAAMD 119

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
             + IV G T++    AV +  I +   G            ++ GD++ V+  L   G  
Sbjct: 120 LEVEIVGGHTEITT--AVVRPVIVSTVFGKSLRGESQTCDLMSEGDLICVTKDLALEGTA 177

Query: 183 IL-----NLREQLGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVH 232
           I+     ++  ++ L  + +         I  ++D       G   + D T GG+   V 
Sbjct: 178 IIVGDHEDIMSKV-LSEDEIKQAKSFMDSISVVKDGVLAGSIGTHGMHDVTEGGILGAVW 236

Query: 233 EFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALH 292
           E       G  + E  +P+    + V + L +D L   + G +V+A+ ++    +  A  
Sbjct: 237 EMCMNSKLGAVIYEDEIPLNDITKKVMKYLDVDPLKMISSGSMVMAISKDKKRAMEEAFK 296

Query: 293 SHPLGKDAALIGEVVERK 310
              +G   ++IGE+V+ K
Sbjct: 297 DAGIG--FSVIGEIVDEK 312


>UniRef50_B0TDV9 Thiamine-monophosphate kinase n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDV9_HELMI
          Length = 373

 Score = 60.8 bits (146), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 77/316 (24%), Positives = 124/316 (39%), Gaps = 59/316 (18%)

Query: 27  FANPWLAEQEDQARLDLAQLV-AEGDRLAFSTDSYVIDPLFFPGGN-------------- 71
            A  W        R  L+ ++ ++G RL    D+ VID    PGG               
Sbjct: 23  LARAWQGAASQGERGGLSPVIPSQGLRLGIGDDAAVID---VPGGKPLLVTTDMLVEGVH 79

Query: 72  ----------IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
                     +G+ A+    +D+A  G IP +      +     +E ++ +   M E A 
Sbjct: 80  FLWSPIRRRLLGRKALAVNISDIAAMGGIPAWAFLSIGVPASAKVEEVEGLYAGMGEMAA 139

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMG-AIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             G+ +  GDT        DK  IN   +G A+ A I  G      GD++LV+GT+GD  
Sbjct: 140 QFGVELAGGDTV-----RSDKWVINVTLLGLAVKAPI--GRSGGRPGDLILVTGTVGDAA 192

Query: 181 ATI------LNLREQLGLDGEL----VSDCAVLTPLIQTLRDIP------------GVKA 218
           A +        + +   +D ++    + +      L++ L  IP            GV A
Sbjct: 193 AGLHLLLMETKMSQAEKMDAQMREAPIGEADRQALLLRHLDPIPRVAEARALVDYGGVTA 252

Query: 219 LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIA 278
           + D + G V++ VH      GCG  +  A LP+ PAVR +    G +   +A  G     
Sbjct: 253 MMDVSDG-VSSEVHHLCRNSGCGARIDLANLPISPAVRRLARREGREVFAWALSGGEDYE 311

Query: 279 VERNAAEQVLAALHSH 294
           +   A E+ +  L  H
Sbjct: 312 LIFTAPEERVPGLIDH 327


>UniRef50_A5N2W0 HypE n=8 Tax=Clostridium RepID=A5N2W0_CLOK5
          Length = 329

 Score = 60.5 bits (145), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 66/281 (23%), Positives = 126/281 (44%), Gaps = 21/281 (7%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+     N G+LA+    ND+A  G  P  L    +L EG  +E +  ++  +++ A+ 
Sbjct: 51  DPITGANINSGRLAVHINCNDIASCGIEPVGLLVTILLPEGASLEDINRLMGEISDEAKK 110

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMG------AIPANIHWGAQTLTAGDVLLVSGT- 175
             + I+ G T+V    AV+K+ I+   +G      A+  +       + A   L + GT 
Sbjct: 111 LNVEILGGHTEVTS--AVNKIVISCTAIGKGDKGKAVSTSGAKEKDDIVATKCLCLEGTS 168

Query: 176 --LGDHGATILNL--REQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVV 231
             + D+   ++ L  +E++      +   +V+   I  L    GV ++ D T GG+   +
Sbjct: 169 IIVNDYEDKLIGLLTKEEINEAKNYIKQISVVKEGI--LSGGFGVNSMHDITEGGILGAL 226

Query: 232 HEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAAL 291
            E A A   G ++ +  LP+      +C    +D L   + G ++I   +   E+++  L
Sbjct: 227 WEIAEASRVGFKVYKDKLPITKITEKICGHYLIDPLKLISSGSMLITTPK--GEELVRML 284

Query: 292 HSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
            +   G  A ++GE+  + G +L    G +  +D P  + L
Sbjct: 285 ENE--GIKACVVGEIT-KGGYKLI-CNGEEEEIDAPGRDEL 321


>UniRef50_Q6AQZ8 Related to hydrogenase expression/formation protein (HypE) n=1
           Tax=Desulfotalea psychrophila RepID=Q6AQZ8_DESPS
          Length = 345

 Score = 60.5 bits (145), Expect = 9e-08,   Method: Compositional matrix adjust.
 Identities = 67/273 (24%), Positives = 119/273 (43%), Gaps = 29/273 (10%)

Query: 63  DPLF----FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
           DP+F     P   +G   +   A+D+AV+G  P +++   +L  G P E  + +++S++ 
Sbjct: 56  DPIFPAPGLPLDIMGWFTVHIGASDIAVTGVKPEFMTYTLLLPLGCPEEDARTIISSISR 115

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHW----GAQTLTAGDVLLVSG 174
            A   GI+IV G T     GAV    +    +        W    GA+    GD++L++ 
Sbjct: 116 AAEDLGISIVGGHTG--WYGAVTVPTVGGVTVWGTADQDAWISPGGAKD---GDLILMTK 170

Query: 175 TLGDHGATILNL----REQLGLDGELVSDCAVLTPLIQTLRD------IPGVKALRDATR 224
                 A +L++    R Q  +  E+++        I  + D      + GV A+ DAT 
Sbjct: 171 GPCIEAAALLSIVHHERLQGNISEEMLATLRARVDQITVVEDALHAFKVGGVHAMHDATE 230

Query: 225 GGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAA 284
           GGV   + E + + G  + +    + +   +  +   L  D     +EG L+ AVE    
Sbjct: 231 GGVQGGLWEMSTSSGLPVMVDFDGVEIPADIVALARELDFDPWQAISEGTLLAAVEPEQV 290

Query: 285 EQVLA-----ALHSHPLGK-DAALIGEVVERKG 311
           ++V        + S+ LGK D++L    V + G
Sbjct: 291 QEVQRVWADLGIDSYILGKFDSSLKENTVLKNG 323


>UniRef50_A9KBN8 Thiamine-monophosphate kinase n=5 Tax=Coxiella burnetii
           RepID=A9KBN8_COXBN
          Length = 320

 Score = 60.1 bits (144), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 64/271 (23%), Positives = 119/271 (43%), Gaps = 21/271 (7%)

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+  P  ++G  A+  + +D+A  GAIP  +     +++   +  LKA        A   
Sbjct: 56  PINTPPRDLGHKALAVSLSDIASMGAIPHTVLLALTIQKTNEI-WLKAFAEGFFSLADRY 114

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            ++++ GD   V +G    L I+    G IP N        T GD++ ++GT+GD G  +
Sbjct: 115 QVSLIGGD---VTQGP---LCISITATGLIPKNEMICRNGATVGDLIYLTGTVGDAGLAL 168

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
             L++   +D  L++     TP I+    + G+ +       GV A + + A A   G +
Sbjct: 169 ALLKQNKKIDPFLLTRLNCPTPRIEAGVALRGIASAAIDISDGVVADLEKMARASQVGAK 228

Query: 244 LSEAALPVKPAVRGVCELLGL--DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           +    LP+  +++  C L      AL   ++ +L   + +  +E +    HS  L  +  
Sbjct: 229 IYVERLPLSDSLKRYCPLKKAWEYALTSGDDYELCFTIPKERSEPLEEVFHS--LDCECR 286

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
            IGE+++ + V          T+  PH  P+
Sbjct: 287 CIGEIIQGESV----------TVIDPHNRPI 307


>UniRef50_C9RLV8 Thiamine-monophosphate kinase n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RLV8_FIBSS
          Length = 328

 Score = 57.8 bits (138), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 66/261 (25%), Positives = 103/261 (39%), Gaps = 24/261 (9%)

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           I    +DV+  G  P+    G  + +    ET   +  ++A+     GI ++ GDT    
Sbjct: 73  IVSNVSDVSSMGGRPKIALFGLCVNKNWSEETRNRIAKAVAQGFERRGITLIGGDTVSGD 132

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA---TILNLREQLGLD 193
            G       +T  +G     I         GD + V+GTLG   A    ++N  E+    
Sbjct: 133 VG-----MFSTTLLGTTDGEISLLRSDAKPGDHVFVAGTLGKSDAGLWILMNHPEEANRF 187

Query: 194 GELVSDCAVLTPLIQTLRDIPGVKALRDATRG-------GVNAVVHEFAAACGCGIELSE 246
             LV        L   + +  G + ++   RG       G+++  +  A + G  IE+ E
Sbjct: 188 PRLVE-----YHLAPKICEDAGAQLVKQGVRGACMDISDGLSSETNHLALSSGVSIEIDE 242

Query: 247 AALPVKPAVRGVCELLGLDALNFANEG--KLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
             LP+ P V  +CE  GL  L FA  G  +  +    N  + +   L   P   +   IG
Sbjct: 243 QKLPIDPDVLEMCEYFGLSPLQFALNGGEEYELLFTSNLTKSIY--LEGAPKMGEIHDIG 300

Query: 305 EVVERKGVRLAGLYGVKRTLD 325
            V    GV L G  GVK  L+
Sbjct: 301 LVSCGNGVYLKGQDGVKALLN 321


>UniRef50_UPI000038DF5E AIR synthase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI000038DF5E
          Length = 343

 Score = 56.6 bits (135), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 30/100 (30%), Positives = 55/100 (55%), Gaps = 3/100 (3%)

Query: 216 VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKL 275
           + ++ DAT GG+   ++E   A G G+ +    + +   +  +C L  +D L   +EG L
Sbjct: 217 ITSMHDATEGGLLNAIYEIGIASGNGLSVDYNKIIIDSDIEKLCNLFNIDPLRSISEGTL 276

Query: 276 VIAVERNAAEQVLAALHSHPLGKDAALIGEVVER-KGVRL 314
           +I V+   A + L  L S   G +A+LIGE+++  KG+++
Sbjct: 277 LITVKEQYAMEFLTILQSS--GIEASLIGEILDNSKGIKI 314


>UniRef50_Q9HHP1 Hydrogenase expression/formation protein n=1 Tax=Halobacterium
           salinarum RepID=Q9HHP1_HALSA
          Length = 231

 Score = 56.6 bits (135), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 2/101 (1%)

Query: 216 VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKL 275
           V A+ DAT  G+   + E A A G  I +S  A+PV   V  VC  LGLD    ++ G L
Sbjct: 106 VTAMHDATECGIQGALVELATAAGVSISVSSDAVPVPEDVSAVCADLGLDPWQVSSRGTL 165

Query: 276 VIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAG 316
           ++ V    A+  +AAL +       A IG V E  GV + G
Sbjct: 166 LVTVPEAHADTAMAALDAR--NTPVAAIGTVSEGSGVTVDG 204


>UniRef50_B8D020 AIR synthase related protein domain protein n=1 Tax=Halothermothrix
           orenii H 168 RepID=B8D020_HALOH
          Length = 348

 Score = 56.2 bits (134), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 65/261 (24%), Positives = 109/261 (41%), Gaps = 24/261 (9%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTS-MAETAR 121
           DP+       G LA+    ND+A  GA P  +    +L    P  T + +V + M E  R
Sbjct: 51  DPITGAVNKAGYLAVHVACNDLASCGARPVGIQVVLLL----PPATEEIMVGNIMEEITR 106

Query: 122 AAG---IAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD 178
           AA    + ++ G T+++ +  V +  I    +G  P + +        GD L+++  LG 
Sbjct: 107 AAASIEVEVIGGHTEILSK--VTEPIITVTAIGKAPRDKYITTGGARPGDELIITKGLGI 164

Query: 179 HGATIL-----NLREQLGLDGELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVN 228
            G  IL      L +  G+  E++         +  L +       GV A+ D T GG+ 
Sbjct: 165 EGTFILASDYAELLKDRGVPPEIIERGQEYISKLSVLEEGLIGAGLGVHAMHDITEGGLY 224

Query: 229 AVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVL 288
             + E   A   G  +  +  PV P    +C+ L LD     + G ++IA       +++
Sbjct: 225 GALDEMVTASKAGFRIKRSQFPVNPETDIICKALDLDPAGLISSGSMLIAAPDGG--KLV 282

Query: 289 AALHSHPLGKDAALIGEVVER 309
             L     G  A++IGE+ E 
Sbjct: 283 DKLARA--GIKASIIGEITEE 301


>UniRef50_C9RAP1 Thiamine-monophosphate kinase n=1 Tax=Ammonifex degensii KC4
           RepID=C9RAP1_AMMDK
          Length = 339

 Score = 55.8 bits (133), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 76/293 (25%), Positives = 124/293 (42%), Gaps = 31/293 (10%)

Query: 42  DLAQLVAEGDRLAFSTDSYVIDPLFF-----PGGNIGKLAICGTANDVAVSGAIPRYLSC 96
           D A ++A GD+    T   +++ + F        ++G   +    +D+A  G  P Y   
Sbjct: 31  DDAAVLAVGDKWFLFTTDVLVEKVHFRWDLASPADVGFKTLAVNVSDIAAMGGRPTYALV 90

Query: 97  GFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAI--- 153
              L    P+E ++     + E A    + +V GD   + R   D  F   A +G +   
Sbjct: 91  TLGLPLDFPVEKVEEFYAGLKEAAEEYEVILVGGD---ITRS--DIFFAGVALLGEVEPG 145

Query: 154 PANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDC---AVLTPLIQ-- 208
            A    GA+    GD+L V+G LG   A ++ L  +  L  E ++         P  +  
Sbjct: 146 KAKFRKGARP---GDILCVTGPLGGAAAGLVLLESKEELLPETMAHFLRRKYRRPDARLE 202

Query: 209 ---TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD 265
               L D   V AL D + G +    H  A A G  + L  AALP+ P  + +   LG+D
Sbjct: 203 AGRILGDFEEVHALIDISDG-LAGDAHHLARASGVEVNLYRAALPIYPPAQELGRRLGID 261

Query: 266 ALNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
              +A     + +L+  VE +A  +V  AL    +G +   +G V E +GV+L
Sbjct: 262 PARWALFGGEDYELLFTVEPSAVGKVAKALEG--VGLNLFPLGFVEEGEGVKL 312


>UniRef50_B2UPF2 Thiamine-monophosphate kinase n=2 Tax=Verrucomicrobiaceae
           RepID=B2UPF2_AKKM8
          Length = 298

 Score = 55.5 bits (132), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 60/222 (27%), Positives = 92/222 (41%), Gaps = 32/222 (14%)

Query: 42  DLAQLVAEGDR-LAFSTDSYVIDPLFFPGGN---IGKLAICGTANDVAVSGAIPRYLSCG 97
           D A +   G+R L   TD  V    F PG +   IG+ A+    +D+   G  P +    
Sbjct: 36  DCAIIRGSGNRQLLLKTDCVVEGMHFLPGTDPELIGRKALARAVSDIGAMGGTPLHALVT 95

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
             +    P+  ++ +   M   AR  GI+I  G++  +     D L IN A  G + A  
Sbjct: 96  LFVHADRPISQVEGIYRGMGRLARQFGISIAGGESSGLP---ADGLIINVALTGEVEAGK 152

Query: 158 HWGAQTLTAGDVLLVSGTL------GDHGATILNLREQLGLDGELVSDCAVLTPLIQTLR 211
                T  AGD++ V+GTL      G H +    +RE     G +++   V T ++  L 
Sbjct: 153 AVLRSTARAGDLIAVTGTLGGSFPTGHHLSFTPRVRE-----GGILAASGVATSMMD-LS 206

Query: 212 DIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
           D             G+   +   AAA G G  + E  LPV+P
Sbjct: 207 D-------------GLGTDLPRLAAASGLGFRIHEELLPVRP 235


>UniRef50_C8WRZ3 Thiamine-monophosphate kinase n=2 Tax=Alicyclobacillus
           acidocaldarius RepID=C8WRZ3_ALIAD
          Length = 323

 Score = 55.1 bits (131), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 77/288 (26%), Positives = 125/288 (43%), Gaps = 29/288 (10%)

Query: 42  DLAQLVAEGDRLAFSTDSYV------IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLS 95
           D   +V  G RLA +TD+ V       D +  P   +G  A+    +D+A  G  P +++
Sbjct: 27  DDCAVVDGGGRLAVTTDAVVEGVHFRRDTMSPP--QMGYRAMAAAVSDIAAMGGQPAWIT 84

Query: 96  CGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
               +    P E + A+   ++E A A G ++V GD    Q      L+++   +G +  
Sbjct: 85  VALAVPPSWPQEDVVAIYDGVSEAAAAFGASVVGGDVVSTQ----GPLWMSITAVGRVER 140

Query: 156 NI-HWGAQTLTAGDVLLVSGTLGDHGA---TILNLREQLGL-DGELVSDCAVLTPLIQTL 210
            +   GA+    GDVL V+G+LG   A    +L  R    +    LV      TP I   
Sbjct: 141 PVTRAGARP---GDVLFVTGSLGGSAAGLDILLGRRAGSAIAQAVLVERHRRPTPRIAFG 197

Query: 211 RDIP--GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALN 268
           R+    G  AL D +  G+ + ++E A A G  +      +P++P V      +G D L 
Sbjct: 198 REAARLGATALDDIS-DGLASELNEIAEASGVRLLFEGDRVPIQPEVTEYARAVGKDPLE 256

Query: 269 FA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGV 312
           +A     + +LV    R+   ++LA   +  +G     IG V E  GV
Sbjct: 257 YALFGGEDYELVGTAPRDVFARLLAV--APVVGTPITAIGRVEEGDGV 302


>UniRef50_A4YFC4 AIR synthase related protein domain protein n=3 Tax=Sulfolobaceae
           RepID=A4YFC4_METS5
          Length = 332

 Score = 54.7 bits (130), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 71/298 (23%), Positives = 119/298 (39%), Gaps = 28/298 (9%)

Query: 50  GDR-LAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMET 108
           GDR L   TD   I P F         A+   A+DV  SG  PRY      L   +  E 
Sbjct: 41  GDRVLVVKTDPVFIVPQF-GMKKASWFAVHILASDVMTSGIPPRYALLDLNLPPSMTDEE 99

Query: 109 LKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQT-LTAG 167
            + +   + E     G+ +V G T   +   V+   +    M  I      G  + +  G
Sbjct: 100 FREMWVGIHEALLEIGVMVVGGHTGRYE--GVNYPMVGGFTMIGIGEKEKLGHPSKVKPG 157

Query: 168 DVLLVSGTLGDHGATILN------LREQLGLDGELVSDCAVLTPLIQTLRD-----IPGV 216
           D ++V+         +L        RE++  D  L  +   +   +   +D       G+
Sbjct: 158 DYVIVTKGPAIEATGLLTNLYPEFFRERMRSD--LFKEALDMYWKMSCWKDGLIASQVGI 215

Query: 217 KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLV 276
             + DAT GG+   + E +   G  I L    L + PAVR V  ++G+D  +  +EG +V
Sbjct: 216 HMMHDATEGGLWNALVEISEVTGKRINLVGERLFINPAVREVTRIVGIDPFSSISEGTMV 275

Query: 277 IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           I  ++   ++ L        G +A ++G V   +GV + G     + ++ P  +P  R
Sbjct: 276 IVTDKEKVKEELLR-----NGIEAEIVGRVESGEGVYVDG-----KRIEKPSEDPFWR 323


>UniRef50_D1B5R8 AIR synthase related protein n=3 Tax=Synergistaceae
           RepID=D1B5R8_THEAS
          Length = 326

 Score = 54.7 bits (130), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 75/284 (26%), Positives = 120/284 (42%), Gaps = 24/284 (8%)

Query: 53  LAFSTDSYVI---DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETL 109
           + +  D Y+I   DP+       G+L +   ANDVA  G  P +L+   I+   + +E  
Sbjct: 44  IKWPGDRYLIFTSDPIVGAVKGAGRLLVRVNANDVAAKGGEPMFLAVTMIIPPSMGVEAA 103

Query: 110 KAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDV 169
            A++  +       G+A+  G T+   R   D   +  A +G+  A     A  +  G +
Sbjct: 104 SAIMEEIHRECCRIGVAVAGGHTEFNDR--YDSPVLMGAMIGS--AQRVLSASEVRPGHL 159

Query: 170 LLVSGTLGDHGATIL-NLREQL-----GLDGELVSDCAVLTPLIQT---LRDIPGVKALR 220
           +LV+  LG  G +IL + RE L     G + E V     LT ++     LRD+     + 
Sbjct: 160 VLVTKHLGIEGMSILAHDREDLLGFLSGEELEEVRSWGELTSVVPEAALLRDL--ASFMH 217

Query: 221 DATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVE 280
           D T GG    + E  +  G  + L E  LP+ P  R     LG D     + G L+  + 
Sbjct: 218 DPTEGGFLGGLGEVESLTGLKVRL-EGDLPIHPLTRRAASQLGFDPTCLISSGSLLAFLP 276

Query: 281 RNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTL 324
               E+    LH    G   +++GEV++      +G   VK  L
Sbjct: 277 PKGLEEAERRLHRA--GIPWSVVGEVLDEP---FSGEVSVKEEL 315


>UniRef50_Q2RZV6 Thiamine-monophosphate kinase n=1 Tax=Salinibacter ruber DSM 13855
           RepID=Q2RZV6_SALRD
          Length = 360

 Score = 54.3 bits (129), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 77/290 (26%), Positives = 116/290 (40%), Gaps = 33/290 (11%)

Query: 42  DLAQLVAEGDRL-AFSTDSYV----IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSC 96
           D A    + DR+   +TD+ V     D  F P  ++G  A+    +DV    A PRY + 
Sbjct: 43  DAAVYRTDEDRVHVMTTDTLVEGVHFDRAFMPMEHLGFKALSVNVSDVVAMNASPRYATV 102

Query: 97  GFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN 156
              + + + +E +  V   + +   A  + IV GDT      +   L I+  G  A    
Sbjct: 103 SIGIPQNVSVEMITTVYEGLKQACDAYDMHIVGGDTNASHGLS---LSISVVGAAAEEDV 159

Query: 157 IH-WGAQTLTAGDVLLVSGTLGDHGA---TILNLREQLGLDGE-LVSDCAVLTPLIQTLR 211
           ++  GAQ    GD + V+G LG   A    +L  RE+L    E    D    + +I+   
Sbjct: 160 VYRTGAQV---GDKICVTGDLGSSYAGLKVLLRNRERLQEQEEDFEPDLDPYSYVIRRHL 216

Query: 212 DIPG-VKALRDATRGGV------------NAVVHEFAAACGCGIELSEAALPVKPAVRGV 258
             P  +K +RD    GV            +A VH    A   G +L E ALP+ P  R  
Sbjct: 217 APPAQLKTVRDWGDAGVQPHALIDISDGLSAEVHHICEAGDLGAQLYEPALPIDPETRNT 276

Query: 259 CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE 308
               G D   +A  G     +     E  L AL      +   ++GE+VE
Sbjct: 277 ATDFGEDVTIYALFGGEDYELVFTIPEDELDALDP----QTYTVVGEIVE 322


>UniRef50_A8MDD6 AIR synthase related protein domain protein n=1 Tax=Caldivirga
           maquilingensis IC-167 RepID=A8MDD6_CALMQ
          Length = 337

 Score = 53.1 bits (126), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 67/267 (25%), Positives = 115/267 (43%), Gaps = 17/267 (6%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+      +G LA+   AND+A  G  PR+     IL        +  ++  + +    
Sbjct: 49  DPVTGSSNLLGWLAVHVAANDIATRGIRPRWFLVTLILPVDYGENDVVNIMRQINDALIE 108

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
              ++V G T+  +  AV +    T  +G     I  G   L  GDV++++         
Sbjct: 109 INASLVGGHTE--KSDAVTRPIAVTTAIGIGSRFIRTGG--LRTGDVIVMTKYAALEATA 164

Query: 183 IL--NLREQLG---LDGELVSDCAVLTPLIQTLRDIPGV----KALRDATRGGVNAVVHE 233
           +L  + R +L     +GE   +   L  ++  + D         ++ D T GGV   + E
Sbjct: 165 VLVSDFRGRLMNVLSEGEF-KEATSLYRMVSVVNDALAAAEYATSMHDPTEGGVLQGLLE 223

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS 293
            A + G  I ++E  +PV P  R V     L+ L   + G L+I V  N A +++  L  
Sbjct: 224 MAYSSGKLIIINEDNIPVLPVTRRVLNAFNLNPLTVLSSGSLLIGVGENDAAKLIGKLRD 283

Query: 294 HPLGKDAALIGEVVE-RKGVRLAGLYG 319
             +G +A++IG+V +   GV + G  G
Sbjct: 284 --MGINASIIGKVTDGEPGVVVKGRSG 308


>UniRef50_B3QYZ8 Thiamine-monophosphate kinase n=1 Tax=Chloroherpeton thalassium
           ATCC 35110 RepID=B3QYZ8_CHLT3
          Length = 373

 Score = 52.8 bits (125), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 71/295 (24%), Positives = 116/295 (39%), Gaps = 44/295 (14%)

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
            D L  P  ++G  AI    +D+    A+P Y      L E L +E ++++   M+  A+
Sbjct: 64  FDLLTTPMEHLGAKAISVNVSDICAMNALPTYAVVSIALSEKLSVEMVESLYKGMSNAAK 123

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTL-GDHG 180
             G+AIV GDT     G    L I+   +G +         T   GDV+ VSG L G H 
Sbjct: 124 EYGLAIVGGDTSASTAG----LVISVTIVGKVKKEKVARRSTAKPGDVVCVSGVLGGSHA 179

Query: 181 ATILNLREQLGLDGELVSDCAV---LTPLIQTLRD------IPGVK-------------- 217
              + +RE+  +   L  D +V     P I   +D      +P  +              
Sbjct: 180 GLKVLMRERKLMLDNLKEDGSVDENYRPEIADYQDAVSRHLLPKARLDIVRLFERRGIVP 239

Query: 218 -ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEG--- 273
            A+ D + G  + + H        G  + E   P+    R V +    +A  +A  G   
Sbjct: 240 TAMIDISDGLASEIKH-ICKESKTGAIIEENKFPIMSHARHVADEFEEEATTYALYGGED 298

Query: 274 -KLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV-ERKGVRLAGLYGVKRTLDL 326
            +L+  +    AE++           D  +IGE+  E  GV +  ++   R +DL
Sbjct: 299 YELLFTLSPEDAEKLQET-------DDVKIIGEIKPEAYGVVMLDMFA--REIDL 344


>UniRef50_Q3ARA0 Thiamine-monophosphate kinase n=11 Tax=Chlorobiaceae
           RepID=Q3ARA0_CHLCH
          Length = 369

 Score = 52.4 bits (124), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 71/303 (23%), Positives = 124/303 (40%), Gaps = 46/303 (15%)

Query: 58  DSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMA 117
           +S   D L  P  ++G  AI    +D+    A+PRY      L      + ++ +   M 
Sbjct: 55  ESVHFDLLTTPLSHLGSKAISVNVSDICAMNALPRYALVSLALPPTFSKKMVEELYGGMV 114

Query: 118 ETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMG-AIPANI--HWGAQTLTAGDVLLVSG 174
             A+A GIAI  GDT   + G    L I+   +G A+P  +    GAQ     D+L V+G
Sbjct: 115 HAAQAYGIAIAGGDTSASRSG----LMISITAIGEALPTQLTRRSGAQ---LDDLLCVTG 167

Query: 175 TLGDHGA-----------TILNLREQLGLDGELVSDCAVLTPLIQT-LRDIPGVKALRDA 222
           TLG   A            + +LR    ++  L++D      L+Q  L     +  +R  
Sbjct: 168 TLGGSMAGLKLLMREKEIMLEHLRNNEPVNRNLLADLDEYRELMQRHLLPTARLDVVRLF 227

Query: 223 TR------------GGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFA 270
            R             G+++ V        CG  L E+ +P+    R + + +  + L +A
Sbjct: 228 HRLGIQPTAMIDISDGLSSEVQHICRHSNCGALLHESRIPIHATTRQLADEMQEEPLTWA 287

Query: 271 ----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV-ERKGVRLAGLYGVKRTLD 325
                E +L+  +     +Q+     +H   +D  +IG +    +G+ L  ++G++  L 
Sbjct: 288 LTGGEEYQLLFTLPEATYQQL-----AHE--RDIHVIGTITPTNEGMVLEEMFGIRIDLT 340

Query: 326 LPH 328
             H
Sbjct: 341 TIH 343


>UniRef50_C1TRR7 Hydrogenase maturation factor n=1 Tax=Dethiosulfovibrio
           peptidovorans DSM 11002 RepID=C1TRR7_9BACT
          Length = 343

 Score = 51.6 bits (122), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 68/287 (23%), Positives = 109/287 (37%), Gaps = 30/287 (10%)

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           +DP+      +G+LA+    ND+A  G  PR+     ++ +    + LK ++    + A+
Sbjct: 50  VDPIVGASEGLGRLAVHVACNDIAAGGIRPRWAQLLVLVPDKGDEDILKDIMEDAVKAAQ 109

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
              + IV G +      A+ +        G+            + GD++ V+  +G  G 
Sbjct: 110 EISVTIVGGHSGYTS--ALSRPLAAVTAFGSAEPGQMVSTGGASEGDIVCVTRGVGLEGT 167

Query: 182 TIL--NLREQLGLDGELVSDCAVLTPLIQTLRDIP--------GVKALRDATRGGVNAVV 231
            IL  +  E+         D A    L   L  +         G  A+ D TRGGV   +
Sbjct: 168 AILAWDYPEECRSKELPEGDIAEARSLADKLSVVEEALKLASLGATAMHDPTRGGVLEAM 227

Query: 232 HEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAAL 291
            E A   G    +   ALP+   V         D +   + G LV+ +   A E+  A L
Sbjct: 228 CEMAQGAGMSFRIDGDALPISETVDRFSRAFDFDPMRMISSGALVVTLPGEAVERAGAEL 287

Query: 292 HS----HPLGKDAALIGEVVER-KGVRLAGLYGVKRTLDLPHAEPLP 333
            S    +P+G        VVER  GV +    G     DL +  P P
Sbjct: 288 GSIAPLYPVG--------VVERGTGVTITSSSG-----DLFYEGPEP 321


>UniRef50_Q0W120 Putative thiamine monophosphate kinase n=2 Tax=Euryarchaeota
           RepID=Q0W120_UNCMA
          Length = 322

 Score = 51.6 bits (122), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 80/301 (26%), Positives = 126/301 (41%), Gaps = 50/301 (16%)

Query: 29  NPWLAEQEDQARLDLAQLVAEGDRLAFSTD--SYVID-PLFFPGGNIGKLAICGTANDVA 85
           +P+L +       D A +    D L  +TD    V D P    G +IG +++  + +DVA
Sbjct: 21  SPYLGD-------DCAVIDNGNDYLVVTTDMLHRVTDFPREMTGEDIGWMSVAVSLSDVA 73

Query: 86  VSGAIPRYLSCGFILEEGLP----METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVD 141
             GA P     G +   G+P    +E +  + T M   A+  G  I+ GDT   Q     
Sbjct: 74  GMGARP----VGVVAAIGIPGDTDIEFIDGIATGMRNCAKCYGTDIIGGDTDQHQ----- 124

Query: 142 KLFINTAGMGAIPAN---IHWGAQTLTAGDVLLVSGTLGDH--GATILNLREQLGLDGEL 196
           +L I T   G +  +   +  GA+    GD+L V+G LG    G  +L    +   +   
Sbjct: 125 ELTIVTTAFGRVNKDQVKLRSGAK---VGDLLCVTGYLGTTAAGFKVLTGEREASPEDRQ 181

Query: 197 VSDCAVLTPLIQ-----TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           +   +   P  +      L   PGV A+ D +  G+   V+E + A   G  +   ALPV
Sbjct: 182 ILFRSFFRPEPRLGEGMILAQYPGVTAMMDVSD-GLGKSVYELSVASKVGFIVYADALPV 240

Query: 252 KPAVRGV----CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
           +   R V     ELL + A+ F  E +L+  V  +    +         G D  +IG+V 
Sbjct: 241 REEARKVARSRTELLDM-AICFGGEFELLFTVNPDEVGNI--------KGVDFTVIGKVT 291

Query: 308 E 308
           E
Sbjct: 292 E 292


>UniRef50_A0L3Z7 Thiamine-monophosphate kinase n=1 Tax=Magnetococcus sp. MC-1
           RepID=A0L3Z7_MAGSM
          Length = 338

 Score = 51.2 bits (121), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 80/282 (28%), Positives = 120/282 (42%), Gaps = 44/282 (15%)

Query: 53  LAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAV 112
           + FS+D+   DP       +G+ A+    +D+A  G +PR+    ++L   +P  T ++ 
Sbjct: 60  IHFSSDA---DPYL-----LGQKALAVNLSDIAAMGGLPRW----YLLSMAVPNRTSQSW 107

Query: 113 VTSMAETARAAG----IAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGD 168
           +   A   +AA     +A+V GDT  V+  A  K+ I    +G I  +          GD
Sbjct: 108 LEEFARGVKAASEMFHVALVGGDT--VRSNA--KIVITVQMLGLIGQHRAVARSGAQVGD 163

Query: 169 VLLVSGTLGDHGATILNLREQLG-LDGELVSDCAVLT-------PLIQ---TLRDIPGVK 217
            L +SGTLGD   +   L   LG L   L  D + L+       P IQ    L+D     
Sbjct: 164 RLYLSGTLGD---SAFGLAHLLGKLPAMLADDVSYLSRRHHLPEPRIQLGMALQDAALAH 220

Query: 218 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEG---- 273
           A  D + G +  + H    A      +    LP   + + V    G  AL  A  G    
Sbjct: 221 ACIDVSDGLLADLQH-ICEASQVSAVVDVEKLPFSESAQRVIAQYGRSALELALTGGEDY 279

Query: 274 KLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV---ERKGV 312
           +L+ A+   AA+QV   +H   +G     IGEVV   ER GV
Sbjct: 280 ELLFAISPGAADQVEKIVHQ--VGVSLVEIGEVVGVGERPGV 319


>UniRef50_C3N8T5 AIR synthase related protein domain protein n=11 Tax=Sulfolobus
           RepID=C3N8T5_SULIY
          Length = 318

 Score = 51.2 bits (121), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 67/286 (23%), Positives = 125/286 (43%), Gaps = 35/286 (12%)

Query: 42  DLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILE 101
           D A L  +G+ L   +D     P+     + G L+I    ND+ + GA  R+++   +L 
Sbjct: 29  DAAVLETKGEYLIVHSD-----PITEAKSDNGFLSIAVACNDINMKGAQCRWVNSVILLS 83

Query: 102 EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGA 161
           +   +  L  +++ ++E     G  +V G T+V     V +  + T  MG   +N     
Sbjct: 84  D---ISHLDGIISGISEACNLIGCKVVGGHTEVTSN--VKQDIVITTAMGT--SNKFLNY 136

Query: 162 QTLTAGDVLLVSGTLGDHGATIL-----NLREQLGLDGELVSDCAVLTPLI----QTLRD 212
           +++  G  +++ G+ G  G  IL      L  + G+  E++         I    + L  
Sbjct: 137 KSVKEGMKVVLVGSPGIEGTWILAKDYSELLLEKGVSREVIEKAKGFKMDIIVQQRALSI 196

Query: 213 IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANE 272
           +  V A+ DAT GGV   + E A A G  + ++   + ++   + + + L +D L   + 
Sbjct: 197 LDYVAAMHDATEGGVMQALLEIAKATGYTVLINLDKIGLRYETKIITKALNIDPLKLISS 256

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGE------VVERKGV 312
           G  ++    N  E++L  +       +A +IGE      V+E KGV
Sbjct: 257 GSFIVI--SNHPEKILERI------SEAYVIGEIKRGDSVLEIKGV 294


>UniRef50_UPI0001BC315E hydrogenase expression/formation protein n=1 Tax=Butyrivibrio
           crossotus DSM 2876 RepID=UPI0001BC315E
          Length = 311

 Score = 51.2 bits (121), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 62/280 (22%), Positives = 104/280 (37%), Gaps = 40/280 (14%)

Query: 62  IDPLFFPGGNIGKLAICGT----------------ANDVAVSGAIPRYLSCGFILEEGLP 105
           ID   F  G+I  L  C T                AN++ VSG     +   F+L +   
Sbjct: 27  IDAASFAVGDIHVLTACATGLTDCAIAPETAVYKAANNIWVSGGELLGIEASFMLPKNYN 86

Query: 106 METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMG---AIPANIHWGAQ 162
              LKA    +          +  G T+V     V +  I+ A  G     P NIH    
Sbjct: 87  EYNLKAYTKRVKAACDKCKTTLAGGHTEVTD--GVKRFCISVAATGIAGTTPVNIH---N 141

Query: 163 TLTAGDVLLVSGTLGDHGATILNLREQLG-----LDGELVSDCAVLTPLIQTLRD----- 212
                D+++      +  A I++  + +         E +S        + T+RD     
Sbjct: 142 VKPGMDIIVTKWIALEEAAMIVSNEDNMAKLCEHFSNEYMSVTGQYADWL-TVRDEAAVA 200

Query: 213 -IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFAN 271
              GV A+ D + GG+   + +FA   GCG E+    +P++     + E   L+     +
Sbjct: 201 MKHGVAAMHDISEGGIFTALWDFAEGSGCGFEVDLKRIPLRQETVEIAEFFHLNPYTMKS 260

Query: 272 EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG 311
            G ++IA +      ++ AL+    G  A +IG   +  G
Sbjct: 261 SGSIIIACDN--GTDMVNALNEE--GIPAVIIGRTTDNNG 296


>UniRef50_B8D469 AIR synthase related protein domain protein n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D469_DESK1
          Length = 340

 Score = 50.8 bits (120), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 59/230 (25%), Positives = 97/230 (42%), Gaps = 22/230 (9%)

Query: 42  DLAQLVAEGDRLAFSTDSYVIDPLFFPG---GNIGKLAICGTANDVAVSGAIPRYLSCGF 98
           D   L+ +G RL +S D+Y I  L  P     +IG +A+ G  +DV V G +P     G 
Sbjct: 39  DARDLLPKGPRLIYSMDAYRIKSLMLPWRTWSDIGWMALTGALSDVVVKGGVPSVAMIGL 98

Query: 99  ILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH 158
            L     +  L+ +V  + E +    + I  GDT      ++D  +I  + MG       
Sbjct: 99  GLSSETDILDLEELVKGLREASNYYDVRITGGDTN----ESLDP-WIAVSVMGFTTCKRP 153

Query: 159 WGAQTLTAGDVLLVSGTLGDHGATILN-LREQLGLDGELVSDCAVLTPL------IQTLR 211
              +    GD+++ +G+ G  G   L+ + E  G+   + +   V   L      + T R
Sbjct: 154 PSRRGARPGDIVIATGSYGSMGFVALHGVVEASGISWVVDNTKRVYLKLEVANVIMSTYR 213

Query: 212 DIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA-VRGVCE 260
            I     + D    G+   + + +   G GI L    LPV PA +R  C+
Sbjct: 214 FIHASMDVSD----GLGYTLEQLSELSGYGILLEN--LPVHPAGLREYCK 257


>UniRef50_Q0ABQ2 Thiamine-monophosphate kinase n=3 Tax=Gammaproteobacteria
           RepID=Q0ABQ2_ALHEH
          Length = 321

 Score = 50.1 bits (118), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 78/260 (30%), Positives = 107/260 (41%), Gaps = 22/260 (8%)

Query: 68  PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAI 127
           P   +G  A+    +D+A  GA PR+      L E +    L A  + +   A    +A+
Sbjct: 57  PPDAVGHKALAVNLSDLAAMGARPRWFQLALTLPE-IDEAWLAAFSSGLHRLAAEQDVAL 115

Query: 128 VTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD--HGATILN 185
           V GDT    RG    L I    MG +            AGD L V+GTLGD   G  +  
Sbjct: 116 VGGDTT---RG---PLTITVQAMGEVAPAQALRRTGARAGDRLYVTGTLGDAAQGLALWQ 169

Query: 186 --LREQLGLD--GELVSDCAVLTPLIQTLRDIPGVKALR-DATRGGVNAVVHEFAAACGC 240
             +R   G D  G L+      TP +   R   G+     D + G +  + H      G 
Sbjct: 170 RGVRSAGGDDPAGFLIDRLHRPTPRMAAGRAAAGLARAAIDISDGLLADLGHLLEGGEGL 229

Query: 241 GIELSEAALPVKPAVRGVCE--LLGLDALNFANEGKLVIAV--ERNAAEQVLAALHSHPL 296
           G  L   +LP+ PA R  CE  L G  AL+  ++ +L+ AV  E  AA Q   AL   P 
Sbjct: 230 GAVLQADSLPLSPAYRAHCEDSLPGRAALSGGDDYELLFAVAPENEAAFQT--ALQHVPA 287

Query: 297 GKDAALIGEVVERKGVRLAG 316
           G     IG + E   + L G
Sbjct: 288 G--CTCIGWITEDSAITLQG 305


>UniRef50_Q2RJB8 Thiamine-monophosphate kinase n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RJB8_MOOTA
          Length = 337

 Score = 50.1 bits (118), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 53/214 (24%), Positives = 84/214 (39%), Gaps = 20/214 (9%)

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            IG   +    +D+A  G IP        L     +E +  +   + E  +  G+ I+ G
Sbjct: 67  EIGYKTMAVNVSDIAAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFGVNIIGG 126

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT    R  V    IN A +G +  +          GD+LLV+G LG   A +  L    
Sbjct: 127 DTVSSPRAMV----INLAILGRVENDACLYRHGAQPGDILLVTGDLGGSAAGLDTLLSPR 182

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGG-----------VNAVVHEFAAACG 239
               E+++         +  R  P V  +R A + G           + A V+  A A  
Sbjct: 183 PAPAEVIAWARA-----RHFRPTPRVVEIRAALKAGGLTAADDISDGLVAEVYTLATASR 237

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEG 273
            GI L   A+P+ PA R +  +   + L++A  G
Sbjct: 238 VGIVLEAGAIPIAPATRQLAAIYHKEPLDYALYG 271


>UniRef50_D2M233 Thiamine-monophosphate kinase n=1 Tax=Bacillus cellulosilyticus DSM
           2522 RepID=D2M233_BACS4
          Length = 327

 Score = 49.3 bits (116), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 59/243 (24%), Positives = 96/243 (39%), Gaps = 20/243 (8%)

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGF-ILEEGLPMETLKAVVTSMAETARAAGI 125
            P  +IG  A+    +D+A  GAIP+Y      I +     + L  +   M E A    +
Sbjct: 58  MPMKSIGHKALAVNISDIAAMGAIPQYYLVSIAIPKTSWKKKELNDIYNGMNELATVWSM 117

Query: 126 AIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN 185
            ++ GDT        D L I+   +G +             GDV+ V+G L   G +   
Sbjct: 118 DLIGGDTVSTN----DALVISVTVIGKVEKERRLLRSNARCGDVVFVTGEL---GLSAYG 170

Query: 186 LREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALR-----------DATRGGVNAVVHEF 234
           L+  L    E + D  +L  L    +  P V+A R           +    G+ +   E 
Sbjct: 171 LQALLEKGYENIDDDELLPYLQAHQKPDPHVRAGRLLANCGYRIALNDISDGLASEAKEI 230

Query: 235 AAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEG-KLVIAVERNAAEQVLAALHS 293
           A A    +EL  AA+P    ++   +    + L +  E  KLV  + +   E++ AA  +
Sbjct: 231 ADASQVTVELDWAAIPTTNKLKEYPQEKQEEWLLYGGEDFKLVGTIGKENWEKLKAAFQA 290

Query: 294 HPL 296
           H L
Sbjct: 291 HSL 293


>UniRef50_A6W2L4 Thiamine-monophosphate kinase n=2 Tax=Marinomonas
           RepID=A6W2L4_MARMS
          Length = 316

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 72/278 (25%), Positives = 119/278 (42%), Gaps = 24/278 (8%)

Query: 42  DLAQL-VAEGDRLAFSTDSYVIDPLFFPGG----NIGKLAICGTANDVAVSGAIPRYLSC 96
           D AQ+ V +G  L FS D+ +++   FP      +IG  A+    +D+A  GA P + + 
Sbjct: 32  DCAQVQVPQGQSLVFSMDT-LVEGRHFPFDADPVDIGYRAVASCVSDLAAMGAKPAFFTL 90

Query: 97  GFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN 156
           G  + E  P + L  +   MAE A   G+A+V GDT    +G    L I     G +  +
Sbjct: 91  GLTIPESDP-QWLAGLAQGMAELAEPIGLALVGGDTT---KG---PLTITLQVHGYVEPD 143

Query: 157 IHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG- 215
           +         GD + V+G LGD  A +  +  +L +  E   D           R I G 
Sbjct: 144 MAVKRSGAKLGDDIYVTGVLGDAAAAVPIVTGELQVSSERF-DYFYDRYWRPQPRLIVGM 202

Query: 216 -----VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA-VRGVCELLGLDALNF 269
                V A+ D + G    + H   A+ G G  ++ + +P+    +R   E     AL  
Sbjct: 203 ALKRVVHAMMDISDGLAQDIQHILKAS-GVGANINASRMPISAELLRWQPESAVALALTG 261

Query: 270 ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
            ++ +L     ++ A ++  AL +  L      +GE+V
Sbjct: 262 GDDYELCFTAPKDQAAEI--ALITQTLSLPCTKVGEIV 297


>UniRef50_B7AVF9 Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus
           ATCC 43243 RepID=B7AVF9_9BACE
          Length = 305

 Score = 48.5 bits (114), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 59/274 (21%), Positives = 109/274 (39%), Gaps = 20/274 (7%)

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ A+    N +A  G  P  ++    + +    + LK ++  +    R  G  I   D 
Sbjct: 38  GRYAVIDACNALACRGGEPEGINAAVTIPDSYDEKLLKKLIADIDAQCRTCGTHI--EDV 95

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
            V     + K  I  +  G     +  G Q       ++ SG++G  G  I+N+ +    
Sbjct: 96  AVSTSQHIRKPVITASAFGRSSEEMPAGMQKAGGNLDIIASGSIGMSG--IMNVLDSHMD 153

Query: 193 DGELVSDCAVLTPLIQTLRDIP-----------GVKALRDATRGGVNAVVHEFAAACGCG 241
           + + V   +V+         +            G   L  A  GG+ A +   AA  GCG
Sbjct: 154 EAKKVYADSVINAAAADAGKLSVADRASLAAGAGASYLVAAGDGGIYAALWRLAADNGCG 213

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
            +++   +PVK  +  +CEL  ++    ++ G +++  E      ++  L+ +  G DA 
Sbjct: 214 FDINLRDIPVKQEIIEMCELFDINPYELSSTGCMLMTAEDGCG--IVDVLNEN--GYDAV 269

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           +IG   + K  ++  L    R LD+P  E   R 
Sbjct: 270 VIGHTTKEKA-KMMHLEDEVRYLDVPRNEESERF 302


>UniRef50_A3HUE4 Hydrogenase expression/formation factor related protein n=1
           Tax=Algoriphagus sp. PR1 RepID=A3HUE4_9SPHI
          Length = 350

 Score = 48.5 bits (114), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 59/254 (23%), Positives = 104/254 (40%), Gaps = 26/254 (10%)

Query: 81  ANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAV 140
           AND+A +G  P+Y      L + L           +    +  G+AI  G T  VQ    
Sbjct: 75  ANDMATTGFAPQYGQFVLNLPDSLSNADFSTYWGYIDRFCKEIGVAITGGHTGFVQ--GQ 132

Query: 141 DKLFINTAGMGAI----PANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGEL 196
           +  F   AG G +    P +    A     GDV+LV+ +       IL +     +  +L
Sbjct: 133 NSTF---AGGGTLITIAPESEMICATGAEEGDVILVTKSCAMTATAILGMSFPETVKNKL 189

Query: 197 VSDC--AVLTPLIQT--LRD----------IPGVKALRDATRGGVNAVVHEFAAACGCGI 242
            +D   +      QT  L+D           P + A+ D T GGV   ++E   A G G 
Sbjct: 190 GTDVYESACQQFYQTSSLKDGLIAAGESEKFPEITAMHDVTEGGVLGAIYEMLIASGKGG 249

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            +    +PV      + +L  LD       G ++I+   + + Q++  L +  +     +
Sbjct: 250 MIENDLIPVGEIASQISKLFDLDPRYCVGAGAMIISCRPDKSAQLIDRLGNENI--SCTV 307

Query: 303 IGEVV-ERKGVRLA 315
           +G+V+ + +G+R++
Sbjct: 308 VGKVLGQDQGIRIS 321


>UniRef50_C5A3X6 Thiamine monophosphate kinase (ThiL) n=4 Tax=Thermococcus
           RepID=C5A3X6_THEGJ
          Length = 319

 Score = 48.1 bits (113), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 78/294 (26%), Positives = 116/294 (39%), Gaps = 50/294 (17%)

Query: 40  RLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFI 99
           RL    LVA  D L   TD     P       +G  A+    +D+A  GA P     GF+
Sbjct: 30  RLGDRWLVATNDMLVRKTDV----PDIMTPEQVGFKAVTMNVSDMASMGAEP----LGFL 81

Query: 100 LEEGLP----METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
              G+P     + L+ +   + E     G+ +++ DT        D L I+ A +G    
Sbjct: 82  FSLGIPGDLDSDYLEGIARGIGEALDFYGLPVLSADTN-----EADDLIIDGAALGITER 136

Query: 156 NI-HWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTL---- 210
            +   GA+    G+++ V+G LG   A  L  +     +G  VSD AV  PL +      
Sbjct: 137 LLTRSGAK---PGELVCVTGDLGRALAGYLVWK-----NGLEVSD-AVRKPLYEKFLEPR 187

Query: 211 ------RDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGL 264
                  ++  V +       G+   ++  A     GIE+   +LP+   V  V ELLGL
Sbjct: 188 ARVREGSELSKVASSAIDISDGLAKELYLLAEMSQVGIEVRPESLPLGKGVEEVAELLGL 247

Query: 265 DALNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
           D    A     E +LV  V     E          L  D ++IG V   KG+ L
Sbjct: 248 DPFEIALASGEEFELVFTVAPEFVES---------LNFDFSVIGRVTRGKGIYL 292


>UniRef50_Q5ZXK3 Thiamine monophosphate kinase (AIR synthase) n=6 Tax=Legionella
           RepID=Q5ZXK3_LEGPH
          Length = 325

 Score = 47.8 bits (112), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 77/299 (25%), Positives = 119/299 (39%), Gaps = 30/299 (10%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGTANDVAVSGAIPRYLSCGFILEEG 103
           V +G  L  STD+ V    F P  +   I   A+    +D+A  GA P +++    L E 
Sbjct: 41  VPDGMHLLVSTDTLVSGIHFLPQWDPYDIACKAVMVNISDMAAMGAQPCWVTLALTLPE- 99

Query: 104 LPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIP---ANIHWG 160
           L    L +    + ++     + ++ GDT    +G    L I    MG  P   A    G
Sbjct: 100 LNQSWLDSFARGIKDSLGLYNVDLIGGDTT---KGP---LSITLTIMGLTPQGQAIRRCG 153

Query: 161 AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG----ELVSDCAVLTPLIQTLRDIPGV 216
           AQ   AGD ++VSG LG  G  +  L E   ++     EL++      P +     +   
Sbjct: 154 AQ---AGDAIMVSGELGAAGLAVKLLDEHKKVNAKDKVELMNKLLHPKPRVDLCHLLRKY 210

Query: 217 KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD-ALNFANEGKL 275
                    G+ A ++   AA G G  L E A+P  P +   C    LD AL+  ++ +L
Sbjct: 211 ATSAIDISDGLGADLNHICAASGVGANLFEEAIPRHPLLNQYCPEQALDLALSGGDDYEL 270

Query: 276 VIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
              V     +     L    L      IG + E+ G+R+       ++ D P  E  PR
Sbjct: 271 CFTVSIQQLDSFNRDLQKENLI--CFPIGVIEEKPGLRI-------QSADSPSKELQPR 320


>UniRef50_B8D6Q8 AIR synthase related protein domain protein n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D6Q8_DESK1
          Length = 331

 Score = 47.4 bits (111), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 56/262 (21%), Positives = 111/262 (42%), Gaps = 21/262 (8%)

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET-A 120
           +DP+       G LA+   +ND+AV G  P++     ++     +E  + + + M +  +
Sbjct: 50  VDPITTGVKKAGYLAVHVASNDIAVRGVTPKWFMPVVLIPRHYSVEEAEELFSDMGKALS 109

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
              G+AI  G T+V     +D+  I    +G     +    +    GD ++V G +G  G
Sbjct: 110 EIHGVAI-GGHTEVTP--GLDRPIIAMTVIGYTNGRV-ISTRDAGEGDYVVVIGRIGGEG 165

Query: 181 ATILNL-----------REQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNA 229
           A ++             R+ +      + D +++   +  ++D   V  + DAT GG+  
Sbjct: 166 AGVIAWDFGDKLLGKVPRDVIEHARSFIYDVSIVKTAL-AIKDY--VNTMHDATEGGILQ 222

Query: 230 VVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLA 289
            + E A+A    I + + A  +   V+ +   + +D L   + G +V  V     + +L 
Sbjct: 223 ALREVASASKKDIVVLDKAFYIDEEVKRITSAVNVDPLRLLSSGCIVATVAPGYLDSLLN 282

Query: 290 ALHSHPLGKDAALIGEVVERKG 311
            L  H  G   +++G V   +G
Sbjct: 283 ELKKH--GIRHSVVGRVTRGEG 302


>UniRef50_C4LAD9 Thiamine-monophosphate kinase n=1 Tax=Tolumonas auensis DSM 9187
           RepID=C4LAD9_TOLAT
          Length = 328

 Score = 47.0 bits (110), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 61/220 (27%), Positives = 92/220 (41%), Gaps = 20/220 (9%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGTANDVAVSGAIPRYLSCGFILEEG 103
           V  G+ LA STD+ V D  FF   +   +G  A+    +D+A  GA PR++S    L + 
Sbjct: 34  VPVGECLAVSTDTLVSDVHFFADVDPVALGHKALAVNLSDLAAMGAQPRWISLALTLPKA 93

Query: 104 LPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQT 163
             +  L          A    +A++ GDT    RG    L I  +  G +PA        
Sbjct: 94  DDV-WLTGFTQGFHALAVKHNVALIGGDTT---RG---PLSITISAKGTVPAAQALRRSG 146

Query: 164 LTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQ-------TLRDIPGV 216
             AGD + VSG+LG     +      L ++ + + DC+      Q        LR I   
Sbjct: 147 AKAGDAIYVSGSLGAAALAVQQRIHNLPINSDALRDCSFRMDYPQPRCELGLALRGI-AT 205

Query: 217 KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVR 256
            AL D + G    ++H   A+ G   E+    LP+  AV+
Sbjct: 206 SAL-DLSDGLSGDLMHILRAS-GVAAEIELTNLPIASAVQ 243


>UniRef50_B7V7Q7 Thiamine monophosphate kinase n=11 Tax=Gammaproteobacteria
           RepID=B7V7Q7_PSEA8
          Length = 322

 Score = 46.6 bits (109), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 12/138 (8%)

Query: 50  GDRLAFSTDSYVIDPLFFPGGN----IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLP 105
           G++LA STD+ +++ + FP G     + + A+  +A+D+A  GA P   +    L +   
Sbjct: 39  GEQLAVSTDT-LVEGVHFPAGCDPFLLAQRALAVSASDLAAMGAAPLAFTLALTLPQA-D 96

Query: 106 METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLT 165
            E L+     +   AR  G+A+V GDT    RG    L +     G +PA          
Sbjct: 97  AEWLQGFARGLDAMARQCGLALVGGDTT---RG---PLSMTLTVFGRVPAGQALTRAGAR 150

Query: 166 AGDVLLVSGTLGDHGATI 183
            GD+L V G LG+ GA +
Sbjct: 151 PGDLLCVGGPLGEAGAAL 168


>UniRef50_A1AS86 Thiamine-monophosphate kinase n=9 Tax=Desulfuromonadales
           RepID=A1AS86_PELPD
          Length = 333

 Score = 46.2 bits (108), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 14/146 (9%)

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DPL      +G+ ++  + +DVA  GAIPR+      +  G P+E L          A  
Sbjct: 67  DPL-----ALGRKSLGVSISDVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAGE 121

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
            G+ ++ GDT   + G    L I+   M     ++        AGD + VSGTLGD  A 
Sbjct: 122 HGVTLIGGDTCSSKNG----LVISVTIMAEQFPHLILRRSGARAGDEIWVSGTLGD-AAL 176

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQ 208
           +L+L E    DG +  + ++L+ L+ 
Sbjct: 177 VLSLLE----DGAVCDEPSLLSRLLD 198


>UniRef50_D0LRS0 Selenide, water dikinase n=1 Tax=Haliangium ochraceum DSM 14365
           RepID=D0LRS0_HALO1
          Length = 381

 Score = 46.2 bits (108), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 8/143 (5%)

Query: 36  EDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRY-L 94
           +D A + L    A G  L  +TD  VI PL     + G +A     +DV   G  P Y L
Sbjct: 76  DDAAVVRLPGDAASGRALVLTTD--VIAPLVDDAESFGAIAATNAVSDVYAMGGRPLYAL 133

Query: 95  SCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIP 154
           +  F  ++ LP+E L+A++   A      G+AIV G T  V+  A   L    A  G + 
Sbjct: 134 NLAFFPDQSLPLEVLRAILRGGARACERMGVAIVGGHT--VRDSA---LKYGLAVTGEVD 188

Query: 155 ANIHWGAQTLTAGDVLLVSGTLG 177
           +   W  +   AG  L+++  LG
Sbjct: 189 SERAWRHEGGRAGQELVLTKALG 211


>UniRef50_A8VUM5 Beta-lactamase domain protein n=1 Tax=Bacillus selenitireducens
           MLS10 RepID=A8VUM5_9BACI
          Length = 332

 Score = 45.8 bits (107), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 51/197 (25%), Positives = 84/197 (42%), Gaps = 19/197 (9%)

Query: 71  NIGKLAICGTANDVAVSGAIPR-YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
           +IG  A+    +D+A  GA+P+ YL    + ++G P E  + +   + E A   G+ ++ 
Sbjct: 62  DIGYKALAVNISDLAAMGAVPKQYLVSLAVPKQGWPDEETRRIYAGLEEAAALYGMDLIG 121

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           GDT        DKL I+    G +  ++         GDV+ V+G LG   A +  L +Q
Sbjct: 122 GDTV----STADKLVISVTVTGIVETSVRLLRANARPGDVIAVTGPLGASLAGLDLLLDQ 177

Query: 190 LGLDGELVSDCAVLTPLIQTLRDIPGVKALR-----------DATRGGVNAVVHEFAAAC 238
              +G  V +      +    R +P VKA R           +    G++    E A A 
Sbjct: 178 --TNGVPVPEMDQDQLIRSHQRPVPQVKAGRLFAELGIRAALNDISDGISREAKEIAEAS 235

Query: 239 GCGIELSEAALPVKPAV 255
           G  + L    +P KP +
Sbjct: 236 GVRMVLDWKRIP-KPDI 251


>UniRef50_C6VU01 Thiamine-monophosphate kinase n=25 Tax=Bacteria RepID=C6VU01_DYAFD
          Length = 340

 Score = 45.4 bits (106), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 63/271 (23%), Positives = 107/271 (39%), Gaps = 33/271 (12%)

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
            D  FFP  ++G   I    +D+A    IPR ++    L     +E +  +   M    +
Sbjct: 61  FDLTFFPLKHLGYKIIAAGVSDIAAMNGIPRQVTVNLALSNRFSVEAVDELYEGMKVACK 120

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD--H 179
              + +V GDT   + G    L I+ +  G +  +      T    D+L V+G LG    
Sbjct: 121 DFNVDLVGGDTTSSRSG----LIISVSAFGKVKKDKIAYRNTAQPNDLLCVTGDLGGAYM 176

Query: 180 GATILNLREQL-----GLDGELV-SDCAVLTPLIQTLR-------DIPGV--KALRDATR 224
           G  +L   +Q+      +  EL   D  +   L    R       D  GV   ++ D + 
Sbjct: 177 GLQLLEREKQVFLANPNMQPELEGKDYVIQRQLRPEARMDVVYELDEAGVIPTSMIDLSD 236

Query: 225 GGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVE 280
           G  + ++H   A  G G  + E  LP+          L +     ALN   + +L+  V 
Sbjct: 237 GLASDLLH-ICAQSGVGAVIFEERLPIDEQTYLAASELNIGAATAALNGGEDYELLFTVS 295

Query: 281 RNAAEQVLAALHSHPLGKDAALIGEVVERKG 311
           ++A EQ+     ++P       IG + ++KG
Sbjct: 296 QSAYEQI----KNNP---KITFIGYITDKKG 319


>UniRef50_B1CC54 Putative uncharacterized protein n=1 Tax=Anaerofustis
           stercorihominis DSM 17244 RepID=B1CC54_9FIRM
          Length = 324

 Score = 45.4 bits (106), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 65/300 (21%), Positives = 124/300 (41%), Gaps = 33/300 (11%)

Query: 53  LAFSTDSYVI--DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLK 110
           L F  D ++I  DP+      IGKL +  + ND+A + A P  +    ++     ++ ++
Sbjct: 39  LDFQNDLFIISTDPITGSKNGIGKLCVNISCNDIATAMARPVAIMITMLIPTYAKIKDVE 98

Query: 111 AVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVL 170
            ++  +  T     + ++ G T+V    +V+K  ++   +G       +     +AGD +
Sbjct: 99  EIIDDILLTCDENNVDLIGGHTEVT--SSVNKFILSGVCIGRKEKRKEFLP---SAGDKV 153

Query: 171 LVSGTLGDHGATILNL-----------REQLGLDGELVSDCAVLTP-LIQTLRDIPGVKA 218
           ++S   G  G+ I  L           +E+     EL++   V+   LI    +   V  
Sbjct: 154 VMSKYAGLEGSAIAALDLEEEVKNILTKEEFEKTRELINHTNVIKEGLIARNHE---VSL 210

Query: 219 LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIA 278
           L DAT GG+   V E A     G  ++   + +    + + E  G+D     + G +++ 
Sbjct: 211 LHDATEGGIFGGVWEMATNSNLGAVINTDDILILDETKKIAEHFGIDPYKLISSG-VMLF 269

Query: 279 VERNAAEQVLAALHSHPLGKD---AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           + +N  E +        L K+   A+ IG + E K +        K  L  P  + L +I
Sbjct: 270 ITKNDKELI------EDLKKENIPASTIGYLTEEKEIYTIK-NNKKEILSPPEQDELYKI 322


>UniRef50_Q0K6Z2 Thiamine monophosphate kinase n=114 Tax=Proteobacteria
           RepID=Q0K6Z2_RALEH
          Length = 381

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 43/132 (32%), Positives = 56/132 (42%), Gaps = 10/132 (7%)

Query: 50  GDRLAFSTDSYVIDPLFFPG---GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPM 106
           G  LA STD  V    FFP     ++G  A+    +D+A  GA PR  +    L E  P 
Sbjct: 97  GHHLAISTDMLVSGRHFFPDVAPRSLGHKALAVNLSDLAAMGAEPRAFTLALALPEADP- 155

Query: 107 ETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTA 166
             L  +   M   A A G  +V GDT    RG    L ++    G +P            
Sbjct: 156 AWLAELADGMLALADAHGCELVGGDTT---RG---PLTLSLTVFGDVPLRAALRRDAARP 209

Query: 167 GDVLLVSGTLGD 178
           GD + +SGTLGD
Sbjct: 210 GDDIWISGTLGD 221


>UniRef50_D2QDU8 Thiamine-monophosphate kinase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QDU8_9SPHI
          Length = 339

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 8/127 (6%)

Query: 55  FSTDSYV----IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLK 110
            STD  V     D  + P  ++G  AI    +D+A    +P  ++    L    P+E + 
Sbjct: 48  LSTDMLVEGIHFDLTYVPLKHLGYKAITFGVSDIAAMNGLPVQVTVSIALSSRFPVEAID 107

Query: 111 AVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVL 170
            +   +     A  + +V GDT   + G    L I+ + +G +P N+     T    DV+
Sbjct: 108 ELYEGIRAACEAYKVDLVGGDTTASRSG----LIISVSVLGKVPKNLITYRNTAKPNDVV 163

Query: 171 LVSGTLG 177
            V+G LG
Sbjct: 164 CVTGDLG 170


>UniRef50_D2RH67 Thiamine-monophosphate kinase n=1 Tax=Archaeoglobus profundus DSM
           5631 RepID=D2RH67_ARCPR
          Length = 298

 Score = 45.1 bits (105), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 66/274 (24%), Positives = 111/274 (40%), Gaps = 33/274 (12%)

Query: 46  LVAEGDRLAFSTDSYVIDPLFFPGG----NIGKLAICGTANDVAVSGAIPRYLSCGFILE 101
           LV  G RLA +TD  + +   FP G     IG LA+    +D+A  GA P +      L 
Sbjct: 31  LVDVGTRLALTTDC-LHEKTDFPKGIKPEEIGHLALAINLSDLASCGAKPLFFLYTITLS 89

Query: 102 EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGA 161
           +   +E  + ++  M   A   G+A+V GDT        D+L I+   +G   A    G 
Sbjct: 90  D-YWIEYFERILKGMKNLADKYGVAVVGGDTDF-----GDELHISGFAIG--KAERFVGR 141

Query: 162 QTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTP---LIQTLRDIPGVKA 218
                GD + V+G LG    ++  L        E+    ++  P   + + LR      +
Sbjct: 142 DGAKVGDKICVTGLLGKAQLSLEQLMNGFS-RYEIAYPDSLFKPEPRVEEGLRIAKHANS 200

Query: 219 LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIA 278
           + D +   +   +H+ A   G GI++ E  +P+    + V     L+   ++  G   + 
Sbjct: 201 MTDIS-DSLAISLHQIAKRSGVGIKIYEEKIPLDHLTKFVDYEKALELFLYSG-GDYELV 258

Query: 279 VERNAAEQVLAALHSHPLGKDAALIGEVVERKGV 312
                +E +               IGEV+E +GV
Sbjct: 259 FTSKKSEYI--------------EIGEVIEDEGV 278


>UniRef50_C5BS83 Thiamine-phosphate kinase n=1 Tax=Teredinibacter turnerae T7901
           RepID=C5BS83_TERTT
          Length = 315

 Score = 44.7 bits (104), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 67/148 (45%), Gaps = 12/148 (8%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGN----IGKLAICGTANDVAVSGAIPRYLSCGFILEE 102
           +   ++LA S D+ V D + FP       + + A+C + +D+A  GA PR+++    L  
Sbjct: 35  IPPSEQLAVSVDTLVAD-VHFPADAEPYLVAERALCVSLSDLAAMGAQPRWITLCLTLP- 92

Query: 103 GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQ 162
                 L      +    +A G ++V GDT    RG    L I+   MG +P       +
Sbjct: 93  AFDEAWLAGFSAGLFSRTKAYGCSLVGGDTT---RG---PLAISVQVMGTVPVGQALRRK 146

Query: 163 TLTAGDVLLVSGTLGDHGATILNLREQL 190
               GD + VSG LGD  A +  +R +L
Sbjct: 147 GAQVGDGIYVSGPLGDGAAALALVRGEL 174


>UniRef50_B0G472 Putative uncharacterized protein n=1 Tax=Dorea formicigenerans ATCC
           27755 RepID=B0G472_9FIRM
          Length = 289

 Score = 44.7 bits (104), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 64/299 (21%), Positives = 118/299 (39%), Gaps = 26/299 (8%)

Query: 53  LAFSTDS-YVIDPLFFPGGN---IGKLAICGTANDVAVSGAIPRYLS---CGFILEEGLP 105
           + F T+   V+  +    GN   IG+ AI    N+V         +    C  + E+   
Sbjct: 1   MKFETEHGCVVSEMATAYGNSKQIGRYAIAAAMNEVLTRAERVDQMEIRVCAPLEEKKTH 60

Query: 106 METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLT 165
           +  +KA     A  AR  G      + ++++       F+    + A      W  +T+ 
Sbjct: 61  LYDVKA---EAARCAREHGQTF--WEPEIIRAAWAAGTFVQVNALAADVKQQAWNKETMR 115

Query: 166 AGDVLLVSGTLGDHGA-TILN-LREQLG--LDGELVSDCAVLTPLIQTLRDIP-----GV 216
           AG  ++++  +G  G   IL+  R +LG    G  +         I   R+I      GV
Sbjct: 116 AGQDIVLTKWIGLEGTLRILDEKRRELGKRFSGTFLHQVEEFRETIFAEREIRVAKAGGV 175

Query: 217 KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLV 276
             +R    GG+ A ++  A     G+ +   A+PV+     +CE   L+    A+ G ++
Sbjct: 176 SVMRQVGEGGIFAALYRLAKEADTGLVVDLKAMPVRQETIEICEYYKLNPYQLASTGNIL 235

Query: 277 IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           +    +  E +  AL       +AA+IG + +     +     + R +D P  + L +I
Sbjct: 236 MIC--DDGEALADALRKEET--EAAVIGRLTDNNDKIIQNGEDI-RYIDRPAPDELMKI 289


>UniRef50_C0GR51 Thiamine-monophosphate kinase n=1 Tax=Desulfonatronospira
           thiodismutans ASO3-1 RepID=C0GR51_9DELT
          Length = 315

 Score = 44.7 bits (104), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 84/315 (26%), Positives = 126/315 (40%), Gaps = 41/315 (13%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNI 72
           +++NSLF     +  +   +D A L           L  S+D ++ D  F    F   +I
Sbjct: 10  EIVNSLFPREHPHMVVGRGDDCAVLKCPA------SLCMSSDLFLEDVHFRTRYFTPEDI 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P   +   I    L  E  +++++SMAE      +A+  GD 
Sbjct: 64  GHKALAVNLSDLAAGGARPLGFNLNLIWPVYLDEEFCRSMLSSMAELGAKFKLALTGGDL 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ--L 190
              +      L +     G  PA      +    GDVL V G  G   A  L+L E+   
Sbjct: 124 SFGK-----SLGLAVCIWGKSPARQMLRGKA-EPGDVLFVVGKAG-LAACGLSLLEENDP 176

Query: 191 GLDG--ELVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAAC--GCGIE 243
           GLD   E V+      PL+   Q L  I  VK L D + G    +  +    C  G G+E
Sbjct: 177 GLDRYPECVAQHLRPRPLVREGQVLAGIEEVKGLMDVSDG----LARDLPRFCRRGTGVE 232

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEG----KLVIAVERNAAEQVLAALHSHPLGKD 299
           +  +   V P V   C   GLD L  A +G     L+ A  R   + V   +       D
Sbjct: 233 IC-SDFRVHPEVAFFCRDRGLDPLATALKGGEDYALLGACTRKGWDTVKKKI------LD 285

Query: 300 AALIGEVVERKGVRL 314
              +G V ++ G+ L
Sbjct: 286 CRRLGTVTDKPGIFL 300


>UniRef50_D1CF57 Thiamine-monophosphate kinase n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CF57_THET1
          Length = 334

 Score = 44.3 bits (103), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 75/296 (25%), Positives = 128/296 (43%), Gaps = 29/296 (9%)

Query: 42  DLAQLVAEGDRLAFST-DSYV--IDPLFFPGG--NIGKLAICGTANDVAVSGAIPRYLSC 96
           D+A L    D+   +T DS V  I  LF   G   +G+ AI    +D+A  G  PR+   
Sbjct: 33  DVAVLRTSSDKYLLATIDSQVEGIHFLFEYTGARQLGEKAIAINVSDIASMGGQPRHALV 92

Query: 97  GFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN 156
              L +   ++ ++ +   +   + A G+ ++ G+    + G    L ++   +G +   
Sbjct: 93  SLALPDSCQLKLVEELYEGIYSASHAYGLDVIGGNISSSRSG----LLVDVCLLGEVEPE 148

Query: 157 IHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSD---CAVLTPLIQ----- 208
                     GD + V+G LG   A    L  +L    E + +    + LTP  +     
Sbjct: 149 HLVLRSGAAPGDGIYVTGWLGSSAAGFELLCSKLRNCDERIWEELTSSHLTPKARLYEAR 208

Query: 209 TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALN 268
           +L     V A+ D + G ++ + H    A G G  +    LP+  AVR V   LG DAL 
Sbjct: 209 SLVATGAVSAMIDISDGLISDLGH-ILEASGVGAVVYTDRLPIATAVREVASTLGKDALR 267

Query: 269 FANEG----KLVIAVERNAAEQVLA--ALHSHPLGKDAALIGEVV-ERKGVRLAGL 317
           +A  G    +L++  +R   + + +   L   PL     LIGE++ +  G++L GL
Sbjct: 268 WALSGGEDYELLLTGDRRVLDGIASDNGLGGTPL----TLIGEILPQSAGLQLEGL 319


>UniRef50_B4D453 Thiamine-monophosphate kinase n=1 Tax=Chthoniobacter flavus
           Ellin428 RepID=B4D453_9BACT
          Length = 306

 Score = 43.9 bits (102), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 47/184 (25%), Positives = 73/184 (39%), Gaps = 24/184 (13%)

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G  A+C   +D+A  G IP +           P++ +KA+   + + AR   + IV G
Sbjct: 75  RVGWKALCRAISDIAAMGGIPAHALITLAAPAATPVDRVKALYAGLRKAARKYDVGIVGG 134

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           +T      +   LF+N A  G +             GD L V+G LG             
Sbjct: 135 ETSR----SPGPLFLNIALTGWVERQQCVLRSGGRPGDSLYVTGRLG------------- 177

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPG---VKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
              G L        P I+  R +      +A+ D +  G+ A +   AAA  CG  + EA
Sbjct: 178 ---GSLAGKHLDFQPRIEEARWLVSHFKPRAMMDLS-DGLAADLPRLAAASQCGYTIDEA 233

Query: 248 ALPV 251
            LP+
Sbjct: 234 CLPL 237


>UniRef50_C4Z424 Hydrogenase expression/formation protein HypE n=1 Tax=Eubacterium
           eligens ATCC 27750 RepID=C4Z424_EUBE2
          Length = 313

 Score = 43.9 bits (102), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 59/272 (21%), Positives = 119/272 (43%), Gaps = 21/272 (7%)

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+LA+    N+++ +  +   +    I++E      LK ++  +      AG+ I  G T
Sbjct: 51  GELAVYRAVNNISAACGVADCIMDTVIIDEKSREIRLKEIIKELDRQCCIAGVGIAGGHT 110

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG-ATILNLR--EQ 189
            V  +  V+   ++   +G    +         AG  ++V+  +G  G  T+++ +  E 
Sbjct: 111 TVSDK--VNSPVVSVMAIG----HQERVQNKAVAGQDIVVTKHIGMSGIRTVIDCKRDEI 164

Query: 190 LGLDGELVSDCAV--LTPLI-----QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           L +  E + + A+   T L+     +         A+ D + GG+ A + + A   G GI
Sbjct: 165 LKVYSEDIINKALGDETELLVAKEAEIFMQESAYGAMHDVSEGGIFAALWDMAEYSGVGI 224

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+    +PVK  +  +CEL  ++     + G L++  +      ++  LH +  G +AA+
Sbjct: 225 EVDLRQIPVKQEIIEICELFNVNPYILDSMGCLLMTCKNGC--DIINMLHQN--GIEAAV 280

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           IG++ +    R+       R L LP  + + R
Sbjct: 281 IGKITDGNN-RIIHNTEEDRYLGLPEQDEIYR 311


>UniRef50_C6X363 Thiamine-monophosphate kinase n=6 Tax=Bacteroidetes
           RepID=C6X363_FLAB3
          Length = 364

 Score = 43.9 bits (102), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 60/265 (22%), Positives = 109/265 (41%), Gaps = 35/265 (13%)

Query: 66  FFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGI 125
           + P  ++G  A+    +D+A   AIP  +  G  +    P+E L+ +   +A   +   +
Sbjct: 84  YVPLKHLGYKAVVVNLSDLAAMNAIPTQILVGLAVSNRFPVEALEEIYEGIALACKRYKV 143

Query: 126 AIVTGDTKVVQRGAVDKLFINTAGMGAIPANI-HWGAQTLTAGDVLLVSGTLG------- 177
            +V GDT     G V  + I   G+      I   GA+     D+L+V+G LG       
Sbjct: 144 DLVGGDTTSSTSGLV--MGITAIGLEQSENLIKRSGAK---PNDLLVVTGDLGGAYLGLQ 198

Query: 178 ----DHGATILNLREQLGLDG-----ELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGV 227
               +H   + N   Q  ++G     E        T + +TL+++     ++ D + G  
Sbjct: 199 ILEREHSVYLANPNMQPEMEGYDYILERQLKPEARTDIKKTLKELDIQPTSMIDVSDGLS 258

Query: 228 NAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNA 283
           + ++H  A     G  L E  +P+        E L L+    A+N   + +L+  +    
Sbjct: 259 SEILH-LADQSKVGFRLYEEKIPMDSLTISTAEELNLNPVMCAMNGGEDFELLFTI---- 313

Query: 284 AEQVLAALHSHPLGKDAALIGEVVE 308
           A +    + +HP   D ++IG  VE
Sbjct: 314 APEDFEKIRNHP---DFSIIGHAVE 335


>UniRef50_A0M637 Thiamine-monophosphate kinase n=43 Tax=Bacteroidetes
           RepID=A0M637_GRAFK
          Length = 351

 Score = 43.5 bits (101), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 64/279 (22%), Positives = 113/279 (40%), Gaps = 36/279 (12%)

Query: 42  DLAQLVAEGDRLAFSTDSYV----IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
           D A L  +  +   STD  V     D  + P  ++G  A+    +D+         ++  
Sbjct: 42  DAAVLNFKNKQTLISTDLLVEGVHFDLAYMPLKHLGYKAVMVNLSDIYAMNGTATQITVS 101

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMG-AIPAN 156
           F      P+E L+ +   +   A+   + ++ GDT     G    L I+   +G A    
Sbjct: 102 FAASNRFPVEALEELYAGIQLAAKLYNVDVIGGDTTSSTSG----LMISVTAIGIAEKEE 157

Query: 157 IHW--GAQTLTAGDVLLVSGTLG--DHGATILNLREQ-LGLDGELVSDCAVLTPLI---- 207
           I +  GA+   A D+L++SG LG    G  +L   +Q    +     D    T LI    
Sbjct: 158 ITYRNGAK---ANDLLVLSGDLGAAYMGLQVLEREKQVFKANPNSQPDLDQYTYLIERQL 214

Query: 208 --QTLRDIPGV--------KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRG 257
             +  +DIP +         ++ D + G  + V+H        G  L E  +P+ PAV  
Sbjct: 215 KPEARQDIPPLLKELEVQPTSMIDISDGLSSEVIH-LCKNSKLGANLFEEKIPLDPAVIS 273

Query: 258 VCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALH 292
           VCE   +D    AL+   + +L+  + ++  +++    H
Sbjct: 274 VCEEFEIDSTMVALSGGEDYELLFTISQDDYDKIKGNPH 312


>UniRef50_C4ZI96 Hydrogenase expression/formation protein n=1 Tax=Eubacterium
           rectale ATCC 33656 RepID=C4ZI96_EUBR3
          Length = 333

 Score = 43.5 bits (101), Expect = 0.010,   Method: Compositional matrix adjust.
 Identities = 49/238 (20%), Positives = 96/238 (40%), Gaps = 15/238 (6%)

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVV 135
           A+    N++   GA P  +    ++        L+  V ++      AGI ++ G T+V 
Sbjct: 70  AVYDALNNIYAMGADPVGIELALLVPTTENEAVLRETVRAIDAVCEKAGIVVLGGHTQVS 129

Query: 136 QRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE 195
           +  AV  + +    +G         +     G  ++V+G +G  G  IL   ++  L+  
Sbjct: 130 R--AVKNIVVTVTAIGEAYEQALTPSSAAAPGMDVIVTGYVGLEGTAILANEKRTELETR 187

Query: 196 L----VSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
                +   A     I T  +       GV A+ DA++GG+   + + A A G G+++  
Sbjct: 188 FSKAFIDKSAAYIDHISTAMEAASAIGAGVAAIHDASQGGIFGALWDMAEASGIGLDIDL 247

Query: 247 AALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
             LP++     + E   ++     + G L+I     AA+           G++A ++G
Sbjct: 248 KKLPIRQDTIEISEFFDINPYKLLSGGSLIII----AADGTRVVRELEKTGQNAVIVG 301


>UniRef50_A1RYZ9 AIR synthase related protein domain protein n=1 Tax=Thermofilum
           pendens Hrk 5 RepID=A1RYZ9_THEPD
          Length = 465

 Score = 43.5 bits (101), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 18/176 (10%)

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  A   +A+++AVS A P       +  EG P E ++ V+ S  E  R  G  +V G 
Sbjct: 54  LGFFAYHYSASNLAVSFARPELAVLSAVFPEGYPGEAVERVLRSFVEECRKYGTRLVGGH 113

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T    RG    L  +T     +        +    GD +++ G +G   A +        
Sbjct: 114 T-ARYRGLELPLLSST-----MVGRAGRRREKPAGGDRVVIVGEVGAEAAWLAG------ 161

Query: 192 LDGELVSDCAVLTPLIQ--TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
             G++  D + LTPL     L++ P +K + D + GGV   + E A   G  +E+S
Sbjct: 162 --GDV--DPSTLTPLPAALALQEEPSIKLMHDVSEGGVIGALLEVAQRYGVALEVS 213


>UniRef50_B4UJS8 Thiamine-monophosphate kinase n=7 Tax=Cystobacterineae
           RepID=B4UJS8_ANASK
          Length = 329

 Score = 43.1 bits (100), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 43/136 (31%), Positives = 64/136 (47%), Gaps = 16/136 (11%)

Query: 50  GDRLAFSTDSYV----IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLP 105
           G+ LA + D+ V     D  F P  ++G  A+    +D+A  GA P +         G P
Sbjct: 48  GEDLAATVDAVVEGVHFDARFTPE-DVGWKALAVNLSDLASMGARPLWALVALAFPRGTP 106

Query: 106 METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAI---PANIHWGAQ 162
            E L+ V   +   ARA  IA+V G+   V R    +L +    +GA+    A +  GA+
Sbjct: 107 PERLEGVARGLGACARAHRIAVVGGN---VSR--ASELSVTVTAVGAVRRGRALLRSGAR 161

Query: 163 TLTAGDVLLVSGTLGD 178
               GD+L+ SGT GD
Sbjct: 162 P---GDLLVASGTFGD 174


>UniRef50_B4RQH6 Thiamine monophosphate kinase n=28 Tax=Neisseriaceae
           RepID=B4RQH6_NEIG2
          Length = 318

 Score = 43.1 bits (100), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 20/212 (9%)

Query: 49  EGDRLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGL 104
           EG  L FS D  + D  FF    P G   K+ +    +D+A  GAIPR++     L E L
Sbjct: 34  EGFDLCFSADMLLKDRHFFADVKPEGLAWKV-LAVNISDMAAMGAIPRWVLLSAALPE-L 91

Query: 105 PMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTL 164
               L+    S    A+  G+ ++ GDT    +G    +  N   +G +P          
Sbjct: 92  DEVWLERFCGSFFGLAKKFGVTLIGGDT---TKG---DMAFNVTIIGELPKGRALRRDAA 145

Query: 165 TAGDVLLVSGTLGDHGATILNLR-EQLGLDGELVSDC--AVLTPLIQT---LRDIPGVKA 218
            AGD + VSG +G   A  LN R ++  L  ++ ++C   +L P  +    L  +P  +A
Sbjct: 146 VAGDDIWVSGRVG-MAAAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLALLPFARA 204

Query: 219 LRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
            +D + G    + H   A+ G G E+   +LP
Sbjct: 205 AQDVSDGLAQDLGHILTAS-GVGAEIWADSLP 235


>UniRef50_Q9V1N8 Probable thiamine-monophosphate kinase n=3 Tax=Pyrococcus
           RepID=THIL_PYRAB
          Length = 310

 Score = 42.7 bits (99), Expect = 0.018,   Method: Compositional matrix adjust.
 Identities = 63/284 (22%), Positives = 113/284 (39%), Gaps = 41/284 (14%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAIC 78
           I SLFM+ F    L +     +L+ + L+   D L + TD     P F    + G+  + 
Sbjct: 10  IISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTDV----PDFMTPEDAGRKVVT 65

Query: 79  GTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRG 138
              +D+A  G  P        +   +  + L+ +   + E ++   + IV+GDT      
Sbjct: 66  MNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTN----- 120

Query: 139 AVDKLFINTAGMGAIPANIHWGAQTL-----TAGDVLLVSGTLGDH-GATILNLR-EQLG 191
             D + I+   +G        G + L       GD++ V+G LG    A +L +R E++ 
Sbjct: 121 EADDIIIDGGSLGI-------GKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIP 173

Query: 192 LDGE--------LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
            + E         V +   L+ L  +  DI            G++  + E A A    I 
Sbjct: 174 REIEEKARNPRARVEEGVKLSSLANSAIDIS----------DGLSKELWEIANASNVRII 223

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQV 287
           + E  LP+  +V+ +       AL    E +L+  + R   E++
Sbjct: 224 IEEERLPISDSVKEIVSDPVKVALASGEEFELLFTIPREKVEEL 267


>UniRef50_B4WXS9 Thiamine-monophosphate kinase n=1 Tax=Alcanivorax sp. DG881
           RepID=B4WXS9_9GAMM
          Length = 333

 Score = 42.7 bits (99), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 67/272 (24%), Positives = 108/272 (39%), Gaps = 27/272 (9%)

Query: 50  GDRLAFSTDSYVIDPLFFPG----GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLP 105
           G +L  + D+ ++D   FP      ++G   +    +D+A  GA P +      L E + 
Sbjct: 64  GQQLVMTQDTSLVD-RHFPADMAPADVGYRCLAVNLSDLAAMGANPLWFLLSLTLPE-VD 121

Query: 106 METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLT 165
            + L      M E A  AGI++V GD   + RG    L ++    G++P  +        
Sbjct: 122 EDWLAEFSRGMFELADQAGISLVGGD---ITRG---PLAVSIQATGSVPPGLALRRDGAR 175

Query: 166 AGDVLLVSGTLGDHGATILNLRE-QLG-LDGELVSDCAVLTPLIQTLRDIPG-VKALRDA 222
            GD + + G  G   A +L L + Q G   G  +       P  +    + G   A  D 
Sbjct: 176 VGDQICLGGVTG---AGLLGLEQWQAGQRHGPAIGHFRRPRPQWELGMALRGQASACIDI 232

Query: 223 TRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERN 282
           + G +  + H   A+ G G  L EAALP  P V   C      AL        ++     
Sbjct: 233 SDGVLADLSHILQASGGLGACLDEAALPEDPPVLAGCSADKQRALQLQGGDDYLLLFTLP 292

Query: 283 AAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
           AA+         P+ +    +G+V  + G+RL
Sbjct: 293 AAQ---------PVPRGCYCLGQVDAQPGIRL 315


>UniRef50_Q57190 Thiamine-monophosphate kinase n=279 Tax=Gammaproteobacteria
           RepID=THIL_HAEIN
          Length = 328

 Score = 42.4 bits (98), Expect = 0.024,   Method: Compositional matrix adjust.
 Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 10/138 (7%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPG---GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEG 103
           V E  +LA +TD+ V +  F P     ++   A+    +D+A  GA P+++S    L   
Sbjct: 36  VPENYQLAITTDTMVENTHFLPTISPEDLAYKAVATNLSDLAAMGAQPKWVSLALTLP-N 94

Query: 104 LPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQT 163
           +    +     S+  T +   + ++ GDT    +G    L I     G +  N       
Sbjct: 95  VDENWISTFSQSLLHTLKQYNVTLIGGDTT---KG---NLSITITAQGFVEKNKGICRHK 148

Query: 164 LTAGDVLLVSGTLGDHGA 181
              GD++ VS TLGD  A
Sbjct: 149 AQIGDLIYVSSTLGDSAA 166


>UniRef50_B3PBC5 Thiamine-monophosphate kinase n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PBC5_CELJU
          Length = 326

 Score = 42.4 bits (98), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 56/221 (25%), Positives = 95/221 (42%), Gaps = 24/221 (10%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGN----IGKLAICGTANDVAVSGAIPRYLSCGFILEE 102
           + EG +LA S D+ ++  + FP G     I + A+    +D+A  GA P + +    L +
Sbjct: 42  IPEGKQLAVSVDT-LVSGVHFPEGAEPALIAERALRTNLSDLAAMGAEPLWFTLALTLPQ 100

Query: 103 GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQ 162
               + L+     +   A+  GIA++ GDT          L ++   MGA+         
Sbjct: 101 A-EEQWLREFSRGLFACAKRYGIALIGGDTTA------GPLSVSIQVMGAVTPGQALRRD 153

Query: 163 TLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVL-------TPLIQ-TLRDIP 214
               GD +LV+ ++GD  A + +L+ ++   G+   D A L        P +Q + R  P
Sbjct: 154 GANLGDFILVTHSVGDGAAALASLQGRVSFSGD---DHAYLHERFYRPEPRLQASARIRP 210

Query: 215 GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAV 255
              A  D + G V  + H    A   G  +   ALP+  A+
Sbjct: 211 FASAALDISDGLVADLQH-ICTASDLGAVIDVEALPLSSAL 250


>UniRef50_D2LH51 Thiamine-monophosphate kinase n=1 Tax=Rhodomicrobium vannielii ATCC
           17100 RepID=D2LH51_RHOVA
          Length = 333

 Score = 42.4 bits (98), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 23/150 (15%)

Query: 53  LAFSTDSYVIDPLFFPGGNIGKLAICGTA---NDVAVSGAIPRYLSCGFILEEGLPM--- 106
           L  +TD+ V    FF   + G  A    A   +D+A   A P      ++L   LP    
Sbjct: 41  LVMTTDALVAGVHFFENDDPGDAAYKAVAVNVSDLAAKAAKP----FAYLLTLALPAAPT 96

Query: 107 -ETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN--IHWGAQT 163
            +  +A    +A    A G++++ GDT V  RG     +++   +G  PA   +  G + 
Sbjct: 97  EDWARAFAEGLARAQAAFGVSLIGGDT-VTARG---PWWLSVTALGDAPARPLVRGGGRP 152

Query: 164 LTAGDVLLVSGTLGDHGATILNLREQLGLD 193
              GDVL V+GTLGD     L L+ +LGLD
Sbjct: 153 ---GDVLYVTGTLGD---AALGLKMRLGLD 176


>UniRef50_B1L7H6 Thiamine-monophosphate kinase n=1 Tax=Candidatus Korarchaeum
           cryptofilum OPF8 RepID=B1L7H6_KORCO
          Length = 320

 Score = 42.4 bits (98), Expect = 0.025,   Method: Compositional matrix adjust.
 Identities = 76/285 (26%), Positives = 117/285 (41%), Gaps = 29/285 (10%)

Query: 40  RLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAI-CGTAN--DVAVSGAIPRYLSC 96
           RL+    V + D ++ STD         PG ++ +LA  C  AN  DVA  GA P    C
Sbjct: 34  RLNEGIYVFKMDMVSSSTD-------LLPGMSLRQLAKKCVVANFSDVASKGARPLLFMC 86

Query: 97  GFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN 156
              L  G+  E   ++     E  R  G  +V GD      G  ++L I+    G +   
Sbjct: 87  SLGLPRGMRDEEFVSIFEGFEEAMRKYGTYLVGGDL-----GESEELIISGFAFGRVEGR 141

Query: 157 IHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGV 216
           +  G      GD+++ +G+ G       +L E L L  E +   A+ +      R   G+
Sbjct: 142 LV-GRGGSRPGDIVMTTGSFGLTWLGFKHLLEGLELP-EGLRRRALKSVYEPEARVEEGI 199

Query: 217 KALRDATR-----GGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFAN 271
                AT       G+   + E + A G G  + E  LP+   V G+   LG D+++ A 
Sbjct: 200 IISNYATSTVDSSDGLYWSLKELSRASGNGFLIEE--LPLDEEV-GL--FLGGDSISAAF 254

Query: 272 EGKLVIAVERNAAEQVLAALHSH--PLGKDAALIGEVVERKGVRL 314
            G     +     E+ +A +      LG +   IG VVE  G+RL
Sbjct: 255 HGGEEYEIVFTLREEDVAKVRDELTVLGVEPIKIGRVVEGGGIRL 299


>UniRef50_D0MD26 Thiamine-monophosphate kinase n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MD26_RHOM4
          Length = 358

 Score = 42.0 bits (97), Expect = 0.030,   Method: Compositional matrix adjust.
 Identities = 59/228 (25%), Positives = 89/228 (39%), Gaps = 26/228 (11%)

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
            D L  P  ++G  AI    +DV    A PRY +    +   + +E ++A    +     
Sbjct: 65  FDRLMTPMEHLGYKAIAVNVSDVVAMNAEPRYATIAVGIPAKISVEMMEAFYRGVRRACE 124

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
             G+ +V GDT       +    +  A M  +      GA+    GD+L VSG LG   A
Sbjct: 125 KYGLVLVGGDTTAAHTLCISVTVVGEARMEDV--IFRRGAR---PGDLLCVSGDLGAAYA 179

Query: 182 TILNLREQLGLDGELVSDCAV-LTP----------------LIQTLRDIPGVK--ALRDA 222
            +  L EQ     E  +D    L P                +I+  RD  GV+  AL D 
Sbjct: 180 GLKILLEQRRALKEKGADYQPDLEPYRYVIQRQLLPEARLDVIRDWRD-RGVRPRALIDV 238

Query: 223 TRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFA 270
           +  G+ + VH       CG  +  +A+PV    R V +    D   +A
Sbjct: 239 S-DGLASEVHHLCRHSNCGAIVYASAIPVALETREVADHFAEDVDTYA 285


>UniRef50_D0KYD5 Thiamine-monophosphate kinase n=1 Tax=Halothiobacillus neapolitanus
           c2 RepID=D0KYD5_HALNC
          Length = 323

 Score = 42.0 bits (97), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 42/138 (30%), Positives = 64/138 (46%), Gaps = 11/138 (7%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGG----NIGKLAICGTANDVAVSGAIPRYLSCGFILEE 102
           V EG+ L  STD  +++   FP      ++G  A+    +D+A  GA P  ++ G  L  
Sbjct: 33  VPEGEHLLVSTD-LLVEGRHFPESTAAFDVGYKAMAVNLSDLAAMGARPLGVTLGLALPS 91

Query: 103 GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQ 162
             P + L+A        A   GI +V GDT    +  V  L +    MG+ P +      
Sbjct: 92  IEP-DWLEAFAKGFYTLAEQHGICLVGGDTV---KSPVLSLAVTI--MGSAPPDRMLTRS 145

Query: 163 TLTAGDVLLVSGTLGDHG 180
              +GD++ V+GTLGD G
Sbjct: 146 GAQSGDLIAVTGTLGDAG 163


>UniRef50_C0ZK37 Thiamin-monophosphate kinase n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZK37_BREBN
          Length = 338

 Score = 42.0 bits (97), Expect = 0.034,   Method: Compositional matrix adjust.
 Identities = 58/258 (22%), Positives = 98/258 (37%), Gaps = 29/258 (11%)

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IG  A+    +DVA  G + RY      +      +  + +   + E  +A G+ ++ G
Sbjct: 65  DIGYKAVISNVSDVAAMGGVARYALVSIAVSPQWTPDECQQIYEGIYEACQAYGVRVIGG 124

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT      A D L ++   +G +             G ++ V+G +G   A +  L +  
Sbjct: 125 DTV----SAPDALHLSVTVLGEVEKGRAIRRSQAKPGQLVFVTGHVGTSAAGLHLLLQ-- 178

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPGVKALR-----------DATRGGVNAVVHEFAAACG 239
           G   E     +  T +    R +  +KA R           +    G+ + + E A A G
Sbjct: 179 GETAERGVSASWETLMDAHQRPVAQIKAGRLLLESGACSALNDVSDGLASELWEIAEASG 238

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I +  A +P+   VR     +  D L +A  G      E       LA  H   + K 
Sbjct: 239 VSILVDAATVPIHDEVREYARHVEKDPLEWAFYGG-----EDYQLVGTLAKSHYEAVSKQ 293

Query: 300 AA-------LIGEVVERK 310
            A       +IGEVVE++
Sbjct: 294 FAVSGVRFTVIGEVVEKR 311


>UniRef50_D2MI54 Thiamine-monophosphate kinase (Fragment) n=1 Tax=Candidatus
           Poribacteria sp. WGA-A3 RepID=D2MI54_9BACT
          Length = 278

 Score = 41.6 bits (96), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 51/215 (23%), Positives = 86/215 (40%), Gaps = 17/215 (7%)

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A     +DVA  G  P Y+     +    P + ++A+   + +      + ++ G
Sbjct: 4   DVGWRAGVANLSDVAAMGGTPLYVLVSIAVPVRTPPKNIRALYRGLQDACAPCNVELIGG 63

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL------ 184
           DT      +   +F++   +G++ AN          GD L V+GT+GD  A +       
Sbjct: 64  DTS----SSPSHVFLSLTIVGSVRANRALTRHGAEVGDRLYVTGTVGDANAGLRILQSHS 119

Query: 185 -NLREQLGLDGE--LVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAAC 238
            NLR       E  L+      TP IQ    L D     A  D +  G+++ V       
Sbjct: 120 NNLRRFSPSAAEKFLIRRHRRPTPRIQVGQLLVDRNLAHAAIDLS-DGLSSDVGHVCEES 178

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEG 273
             G E+   ALP+   +R   +   LD +  A +G
Sbjct: 179 QVGAEIRGEALPLSSPLRAFAKRHDLDPMELALQG 213


>UniRef50_D1U5K6 Thiamine-monophosphate kinase n=1 Tax=Desulfovibrio aespoeensis
           Aspo-2 RepID=D1U5K6_9DELT
          Length = 317

 Score = 41.6 bits (96), Expect = 0.040,   Method: Compositional matrix adjust.
 Identities = 53/197 (26%), Positives = 78/197 (39%), Gaps = 16/197 (8%)

Query: 40  RLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVSGAIPRYLS 95
           R D   ++A G  +  S+D ++ D  F    F   +IG  A+    +D+A  GA P   +
Sbjct: 26  RGDDCAVLAGGSDICVSSDLFLEDVHFRRGYFTAEDIGYKALAVNISDIAAMGARPFAFT 85

Query: 96  CGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
              ++   L  +        M+  AR   +A+  GD     R  V    I+  G+G    
Sbjct: 86  MDLMIPPDLDEDFWNGFFKGMSALARHNDLALAGGDLSRADRLGVS---ISIFGVGGSKG 142

Query: 156 NIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTP-------LIQ 208
                      GD+L   G LG   A ++ L E LG  G      AVL         LI 
Sbjct: 143 RF-LTRGNCAPGDILFTVGDLGLARAGLMTL-EALGEKGREAFPTAVLAHLRPKPKVLIG 200

Query: 209 TLRDIPGVKALRDATRG 225
           TL +  G+K L D + G
Sbjct: 201 TLLNAAGIKGLMDVSDG 217


>UniRef50_B5FBG0 Thiamine-monophosphate kinase n=7 Tax=Vibrionaceae
           RepID=B5FBG0_VIBFM
          Length = 332

 Score = 41.6 bits (96), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 65/282 (23%), Positives = 116/282 (41%), Gaps = 35/282 (12%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGTANDVAVSGAIPRYLSCGFILEEG 103
           V EG ++A +TD+      F    +   +G  A+    +D+A  GA P ++S    L + 
Sbjct: 35  VPEGYQVAITTDTLAAGTHFLADADPVSVGHKALASNLSDLAAMGAKPTWVSLALTLPQS 94

Query: 104 LPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQT 163
              + L+       + A+   + ++ GDT    +G    L I     G IP         
Sbjct: 95  -DEKWLEGFCRGFFDLAKQYQVELIGGDTT---KGP---LSITITVQGIIPKGSALTRSA 147

Query: 164 LTAGDVLLVSGTLGDHGA---TILNLREQLG--LDGELVSDCAVLTPLIQTLRDIPGV-K 217
              GD + V+G LGD  A    ILN  + +   L+ EL       TP ++  +DI  +  
Sbjct: 148 AQIGDDIYVTGNLGDSAAGLEVILNSHKNVKGELEKELEKRHYYSTPQVELAQDIRHLCH 207

Query: 218 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAV-------RGVCELLGLDALNFA 270
           A  D + G ++ + H    +    + ++   LP+   +       +  C+ L   AL   
Sbjct: 208 AALDISDGVISDLGHILKQSNVSAV-INVNNLPISSELVTYYRQDKEKCQKL---ALTSG 263

Query: 271 NEGKLVIAV---ERNAAEQVLAALHSHPLGKDAALIGEVVER 309
            E +L        R A +Q+   L+     K  ++IGE++++
Sbjct: 264 EEYELCFTASKKNRKAIKQIATILN-----KKISIIGEIIDK 300


>UniRef50_Q214H1 Thiamine-monophosphate kinase n=2 Tax=Rhizobiales
           RepID=Q214H1_RHOPB
          Length = 338

 Score = 41.6 bits (96), Expect = 0.041,   Method: Compositional matrix adjust.
 Identities = 45/143 (31%), Positives = 63/143 (44%), Gaps = 14/143 (9%)

Query: 42  DLAQLVAEGDRLAFSTDSYVIDPLFFPGG---NIGKLAICGTANDVAVSGAIPRYLSCGF 98
           D A L + GD L  +TD+ V    F P     +I + A+    +D+A  GA P     GF
Sbjct: 41  DCAILTSSGDDLVLTTDAIVEGVHFLPDDPPESIARKALRVNLSDLAAKGASP----AGF 96

Query: 99  ILEEGLPM---ETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
           +L   L       L     ++ E A A G  ++ GDT V   G    L I+    G +PA
Sbjct: 97  LLTLALRSAEESWLAPFAKALGEDAAAFGCPLLGGDT-VSTPG---PLMISVTAFGRVPA 152

Query: 156 NIHWGAQTLTAGDVLLVSGTLGD 178
                      GD ++VSGT+GD
Sbjct: 153 GRMVRRAGARPGDHVVVSGTIGD 175


>UniRef50_Q3II30 Thiamin-monophosphate kinase n=3 Tax=Alteromonadales
           RepID=Q3II30_PSEHT
          Length = 326

 Score = 41.6 bits (96), Expect = 0.043,   Method: Compositional matrix adjust.
 Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 10/152 (6%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGTANDVAVSGAIPRYLSCGFILEEG 103
           V +  +LA +TD+ V    FF       +G  A+    +D+A  GA P ++S    L   
Sbjct: 36  VPQNCQLAITTDTLVAGVHFFDDIEPRALGHRALAVNLSDLAAMGAEPTWVSIALTLP-S 94

Query: 104 LPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQT 163
           +  + ++ +   M E A    + I+ GDT          L I     G +P         
Sbjct: 95  IDQQWIEELTDGMHEIAEYFNVQIIGGDT------TQGPLSITICAKGTVPEGTALCRNG 148

Query: 164 LTAGDVLLVSGTLGDHGATILNLREQLGLDGE 195
              GD + V+G LGD G  I + ++ L ++ E
Sbjct: 149 AKVGDWIFVTGPLGDAGLAIESRKQGLTIEPE 180


>UniRef50_B8KML1 Putative thiamine-monophosphate kinase n=1 Tax=gamma
           proteobacterium NOR5-3 RepID=B8KML1_9GAMM
          Length = 366

 Score = 41.2 bits (95), Expect = 0.048,   Method: Compositional matrix adjust.
 Identities = 57/245 (23%), Positives = 93/245 (37%), Gaps = 39/245 (15%)

Query: 51  DRLAFSTDSYVIDPLF---FPGGN-IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPM 106
           +RL  +TD   +   +     GG  IG  A+    +D+  +G IP  +S   +L     +
Sbjct: 58  ERLLVNTDRSGVSKAYTLGLAGGECIGDFAVSHAVSDILATGGIPFAVSVAMLLPGSTSV 117

Query: 107 ETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTA 166
           + +  +V  + E      + I  GDTK       +KL +    +G    +      T   
Sbjct: 118 KLVDEIVDGIVEACAEFDVTITGGDTK-----KAEKLSLVVTALGRASEDRLLFRDTPKV 172

Query: 167 GDVLLVSGTLGDH-GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVK-------- 217
           GD L+VSG LG     +I++ R               ++ LIQ L D   V+        
Sbjct: 173 GDQLVVSGFLGSMLMGSIIHKRHH------------KVSELIQKLVDEALVRQRPPYRLA 220

Query: 218 ----ALRDAT-----RGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALN 268
               A R AT       G+ +           G+EL    +P+ PA+  + + L L  L 
Sbjct: 221 MEMGAARIATACTDISDGLPSACRNMVEKSNLGVELFADNIPIHPALESLLKTLSLTPLQ 280

Query: 269 FANEG 273
            +  G
Sbjct: 281 LSMAG 285


>UniRef50_B9ZS01 Thiamine-monophosphate kinase n=1 Tax=Thioalkalivibrio sp. K90mix
           RepID=B9ZS01_9GAMM
          Length = 324

 Score = 41.2 bits (95), Expect = 0.050,   Method: Compositional matrix adjust.
 Identities = 69/229 (30%), Positives = 93/229 (40%), Gaps = 28/229 (12%)

Query: 47  VAEGDRLAFSTDSYVIDPLFFPG---GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEG 103
           V  G  L  S D+ V    +FP     ++G  A+    +D+A  GA P     G +L   
Sbjct: 38  VQAGHELVVSVDTMVEGTHYFPDHPPASLGHKALAANLSDLAAMGADP----LGAVLSLT 93

Query: 104 LP---METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWG 160
           LP    + L A        A  A + +V GDT    RG      I+   +G +PA     
Sbjct: 94  LPSVDHDWLAAFSRGFLALAEQASVPLVGGDTT---RGPG---AISVTVLGQVPAGQALR 147

Query: 161 AQTLTAGDVLLVSGTLGDHGATIL---NLREQLGLDGELVSDCAVLTPLIQTLRDIPGVK 217
                 GD L+VSG LG   A +      R Q     E   DCA L     + R   G +
Sbjct: 148 RAGARPGDRLVVSGALGGAAAGLAFEKQRRAQGRPPDEESPDCARL--FWPSARLALG-R 204

Query: 218 ALRDATRG------GVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCE 260
            LR+  R       G+ A +   AAACGCG  +  + LPV P + G  E
Sbjct: 205 GLRNRARAVIDISDGLLADLGHLAAACGCGARVDWSQLPVDPLLEGQPE 253


>UniRef50_Q65TX9 ThiL protein n=4 Tax=Pasteurellaceae RepID=Q65TX9_MANSM
          Length = 331

 Score = 41.2 bits (95), Expect = 0.057,   Method: Compositional matrix adjust.
 Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 11/139 (7%)

Query: 43  LAQLVAEGDRLAFSTDSYVIDPLFFPG---GNIGKLAICGTANDVAVSGAIPRYLSCGFI 99
           + QL A+  RLA +TD+ V +  F+P      +G  A+    +D+A  GA P ++S    
Sbjct: 34  ITQLKAD-QRLAVTTDTMVENSHFYPTIPPRALGYKAVATNLSDLAAMGATPTWVSLALT 92

Query: 100 LEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHW 159
           L +      L      M E      + ++ GDT    +G +  + I   G+    A    
Sbjct: 93  LPKT-DSHWLNEFSKGMFEILNRYDVTLIGGDTT---KGEIPTVTITAQGLLGDYALCRH 148

Query: 160 GAQTLTAGDVLLVSGTLGD 178
            A+    GD + VSGTLGD
Sbjct: 149 QAKI---GDWIYVSGTLGD 164


>UniRef50_Q5FNA0 Thiamin-monophosphate kinase n=1 Tax=Gluconobacter oxydans
           RepID=Q5FNA0_GLUOX
          Length = 325

 Score = 40.8 bits (94), Expect = 0.070,   Method: Compositional matrix adjust.
 Identities = 37/147 (25%), Positives = 62/147 (42%), Gaps = 9/147 (6%)

Query: 49  EGDRLAFSTDSYVIDPLFFPGG---NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLP 105
           EG+  A STD+ V +  F P      +G+  +    +D+A  GA P   +    +  G  
Sbjct: 44  EGEEFAISTDTMVENVHFLPDDPPETLGRKLLRCNLSDLAAMGARPHAYTLNVTVTRGGR 103

Query: 106 MET--LKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQT 163
            +     A    +AE  +  G+ ++ GDT  +       L ++    G +  N      T
Sbjct: 104 HDENWFAAFSRGLAEDQQRYGVHLIGGDTTSIS----GPLVLSATVFGLLRHNTALRRST 159

Query: 164 LTAGDVLLVSGTLGDHGATILNLREQL 190
              GD + V+GT+GD    +L L+  L
Sbjct: 160 ARPGDEIWVTGTIGDAALGLLVLQGSL 186


>UniRef50_C6QHP2 Thiamine-monophosphate kinase n=1 Tax=Hyphomicrobium denitrificans
           ATCC 51888 RepID=C6QHP2_9RHIZ
          Length = 341

 Score = 40.4 bits (93), Expect = 0.088,   Method: Compositional matrix adjust.
 Identities = 59/226 (26%), Positives = 91/226 (40%), Gaps = 29/226 (12%)

Query: 48  AEGDRLAFSTDSYVIDPLFFPG---GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGL 104
           A G  L FS+D  +    FF      +I   A+   A+D+A  GA P      ++L   L
Sbjct: 49  ASGSDLVFSSDPIIAGVHFFHDDRPADIAWKALACNASDMAAKGAAP----VAYLLTLAL 104

Query: 105 PMETLKAVVTSMAETARAA----GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWG 160
           P    +  + + A+  RAA    G  ++ GDT V        L I    +G++ A     
Sbjct: 105 PEAPERDWIAAFADGLRAAQSEFGCKLIGGDTDVTP----GPLSIGITIIGSVAAGAFIP 160

Query: 161 AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGV---- 216
                AGD + VSGT+GD  A  L LR        L  D   L  L + LR  P +    
Sbjct: 161 RGGAKAGDHVFVSGTIGD-AALGLALRRDPSQFSTLTDDQRALL-LDRYLRPKPRLALAG 218

Query: 217 ------KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVR 256
                 ++  D + G +  +     A+ G  ++  +  +P+ P  R
Sbjct: 219 PVRSHARSALDVSDGLIKDLRRLAGASLGIAVKFDD--IPLSPPAR 262


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A6VPG0 Hydrogenase expression/formation protein HypE n=...   421   e-116
UniRef50_C1F4L5 Hydrogenase expression/formation protein HypE n=...   390   e-107
UniRef50_C1DUF0 Hydrogenase expression/formation protein HypE n=...   387   e-106
UniRef50_C6PIR8 Hydrogenase expression/formation protein HypE n=...   385   e-105
UniRef50_P31906 Hydrogenase expression/formation protein hypE n=...   376   e-103
UniRef50_P40599 Hydrogenase expression/formation protein hypE n=...   375   e-102
UniRef50_B8D1S4 Hydrogenase expression/formation protein HypE n=...   371   e-101
UniRef50_A4XJQ3 Hydrogenase expression/formation protein HypE n=...   370   e-101
UniRef50_Q0HUQ3 Hydrogenase expression/formation protein HypE n=...   367   e-100
UniRef50_B2TM78 Hydrogenase expression/formation protein HypE n=...   366   e-100
UniRef50_B0TWC9 Hydrogenase expression/formation protein HypE n=...   362   1e-98
UniRef50_C6PPZ0 Hydrogenase expression/formation protein HypE n=...   361   2e-98
UniRef50_B7JZ80 Hydrogenase expression/formation protein HypE n=...   360   3e-98
UniRef50_C5ZXL6 Hydrogenase expression/formation protein HypE n=...   360   5e-98
UniRef50_B0TCN4 Hydrogenase expression/formation protein hype n=...   358   2e-97
UniRef50_D2ATM4 Hydrogenase maturation factor-like protein n=35 ...   358   2e-97
UniRef50_A4CGN3 Hydrogenase expression/formation protein HypE n=...   357   3e-97
UniRef50_D1BLS0 Hydrogenase expression/formation protein HypE n=...   356   9e-97
UniRef50_A8ZNR3 Hydrogenase expression/formation protein HypE n=...   356   9e-97
UniRef50_UPI0001C42969 hydrogenase expression/formation protein ...   354   2e-96
UniRef50_A6LXR5 Hydrogenase expression/formation protein HypE n=...   353   5e-96
UniRef50_P31905 Hydrogenase expression/formation protein hypE n=...   351   2e-95
UniRef50_Q39ZF9 Hydrogenase expression/formation protein HypE n=...   351   2e-95
UniRef50_Q58089 Putative hydrogenase expression/formation protei...   348   3e-94
UniRef50_B2UW48 Hydrogenase expression/formation protein n=12 Ta...   346   7e-94
UniRef50_B7JF80 Hydrogenase expression/formation protein HypE n=...   346   9e-94
UniRef50_A7I1Q2 Hydrogenase expression/formation protein HypE n=...   346   9e-94
UniRef50_B9KGD0 Hydrogenase expression/formation protein HypE n=...   344   4e-93
UniRef50_B4U670 Hydrogenase expression/formation protein HypE n=...   343   4e-93
UniRef50_C3XF65 Hydrogenase expression/formation protein n=3 Tax...   343   6e-93
UniRef50_A4YFA3 Hydrogenase expression/formation protein HypE n=...   342   1e-92
UniRef50_C1SLC8 Hydrogenase expression/formation protein HypE n=...   341   2e-92
UniRef50_B5YJH9 Hydrogenase expression/formation protein HypE n=...   337   4e-91
UniRef50_A6C222 Hydrogenase expression/formation protein HypE n=...   337   4e-91
UniRef50_B4S328 Hydrogenase expression/formation protein HypE n=...   335   1e-90
UniRef50_C8PGA7 Hydrogenase expression/formation protein HypE n=...   333   5e-90
UniRef50_C9LR03 Hydrogenase expression/formation protein HypE n=...   332   1e-89
UniRef50_C9KK60 Hydrogenase expression/formation protein HypE n=...   328   2e-88
UniRef50_B2KBC5 Hydrogenase expression/formation protein HypE n=...   322   9e-87
UniRef50_D1VJK8 Hydrogenase expression/formation protein HypE n=...   317   5e-85
UniRef50_D2LQB8 Hydrogenase expression/formation protein HypE n=...   313   6e-84
UniRef50_A4TCL4 Hydrogenase expression/formation protein HypE n=...   312   8e-84
UniRef50_C7NVH7 Hydrogenase expression/formation protein HypE n=...   311   2e-83
UniRef50_A8A9S1 Hydrogenase expression/formation protein HypE n=...   311   2e-83
UniRef50_B5Y920 Hydrogenase expression/formation protein HypE n=...   311   2e-83
UniRef50_D1Y5N1 Hydrogenase expression/formation protein HypE n=...   311   2e-83
UniRef50_A7H7N3 Hydrogenase expression/formation protein HypE n=...   310   5e-83
UniRef50_D1A5C3 Hydrogenase expression/formation protein HypE n=...   309   7e-83
UniRef50_C1TK23 Hydrogenase expression/formation protein HypE n=...   306   6e-82
UniRef50_Q8NKU8 Membrane-bound NiFe hydrogenase n=1 Tax=Acidianu...   302   1e-80
UniRef50_C5CEU2 Hydrogenase expression/formation protein HypE n=...   302   2e-80
UniRef50_A5EUI7 Hydrogenase expression/formation protein n=4 Tax...   301   3e-80
UniRef50_B1YBW5 Hydrogenase expression/formation protein HypE n=...   287   4e-76
UniRef50_A3Z0T5 Hydrogenase expression/formation protein; HypE n...   285   2e-75
UniRef50_D2RDT5 Hydrogenase expression/formation protein HypE n=...   275   1e-72
UniRef50_A3DKG6 Hydrogenase expression/formation protein HypE n=...   274   3e-72
UniRef50_B6YVE6 HypE n=9 Tax=Thermococcaceae RepID=B6YVE6_THEON       272   2e-71
UniRef50_B8D3R7 Hydrogenase expression/formation protein HypE n=...   271   3e-71
UniRef50_A1S0T2 AIR synthase related protein domain protein n=2 ...   250   4e-65
UniRef50_B7R791 AIR synthase related protein, C-terminal domain ...   242   1e-62
UniRef50_B8I2N9 AIR synthase related protein domain protein n=6 ...   240   7e-62
UniRef50_C7G8J7 Hydrogenase maturation factor n=4 Tax=Clostridia...   239   8e-62
UniRef50_C3N301 AIR synthase related protein domain protein n=9 ...   238   1e-61
UniRef50_B0KA39 AIR synthase related protein domain protein n=10...   237   4e-61
UniRef50_C7NS45 AIR synthase related protein domain protein n=1 ...   237   6e-61
UniRef50_A8MLK1 AIR synthase related protein domain protein n=3 ...   237   6e-61
UniRef50_A8ZNV6 Hydrogenase expression/formation protein HypE n=...   235   2e-60
UniRef50_Q97BE7 Hydrogenase expression formation protein HypE n=...   230   4e-59
UniRef50_C9L525 Hydrogenase maturation factor n=1 Tax=Blautia ha...   230   5e-59
UniRef50_A4YFC4 AIR synthase related protein domain protein n=3 ...   230   5e-59
UniRef50_A5N2W0 HypE n=8 Tax=Clostridium RepID=A5N2W0_CLOK5           229   1e-58
UniRef50_B8GHF5 AIR synthase related protein domain protein n=1 ...   229   1e-58
UniRef50_D1VUU5 Hydrogenase maturation factor n=1 Tax=Peptoniphi...   226   1e-57
UniRef50_A4XL04 AIR synthase related protein domain protein n=2 ...   226   1e-57
UniRef50_B9KYQ7 Hydrogenase expression/formation n=2 Tax=Thermom...   224   3e-57
UniRef50_Q2RKM3 AIR synthase related protein-like n=1 Tax=Moorel...   223   5e-57
UniRef50_D1C5Z5 AIR synthase related protein domain protein n=7 ...   223   7e-57
UniRef50_C0CMS4 Putative uncharacterized protein n=2 Tax=Clostri...   220   5e-56
UniRef50_B8D020 AIR synthase related protein domain protein n=1 ...   218   2e-55
UniRef50_B5Y6B6 Hydrogenase expression/formation protein HypE n=...   216   8e-55
UniRef50_A8MDD6 AIR synthase related protein domain protein n=1 ...   214   3e-54
UniRef50_A4WH94 AIR synthase related protein domain protein n=5 ...   213   5e-54
UniRef50_A3DLS7 AIR synthase related protein domain protein n=1 ...   212   1e-53
UniRef50_B6YUV4 HypE n=3 Tax=Thermococcus RepID=B6YUV4_THEON          211   4e-53
UniRef50_B0R9W2 Hydrogenase expression/formation protein n=3 Tax...   209   1e-52
UniRef50_C7H113 Hydrogenase maturation factor n=1 Tax=Eubacteriu...   209   1e-52
UniRef50_C6A3P3 Hydrogenase expression/formation protein HypE n=...   207   4e-52
UniRef50_Q6KZH8 AIR Synthase n=1 Tax=Picrophilus torridus RepID=...   207   4e-52
UniRef50_UPI0001B4B0DD hydrogenase expression/formation protein ...   207   5e-52
UniRef50_D2RZQ8 AIR synthase related protein domain protein n=1 ...   205   1e-51
UniRef50_Q9YA95 Putative hydrogenase expression/formation protei...   205   2e-51
UniRef50_Q6AQZ8 Related to hydrogenase expression/formation prot...   198   2e-49
UniRef50_Q5ZXK3 Thiamine monophosphate kinase (AIR synthase) n=6...   198   2e-49
UniRef50_C1TRR7 Hydrogenase maturation factor n=1 Tax=Dethiosulf...   197   4e-49
UniRef50_UPI000038DF5E AIR synthase n=1 Tax=Ferroplasma acidarma...   194   3e-48
UniRef50_B8D6Q8 AIR synthase related protein domain protein n=1 ...   193   9e-48
UniRef50_C9RAP1 Thiamine-monophosphate kinase n=1 Tax=Ammonifex ...   192   2e-47
UniRef50_A1HSU1 Thiamine-monophosphate kinase n=1 Tax=Thermosinu...   191   3e-47
UniRef50_B0R2T1 Hydrogenase expression/formation protein n=2 Tax...   188   3e-46
UniRef50_A9KBN8 Thiamine-monophosphate kinase n=5 Tax=Coxiella b...   187   5e-46
UniRef50_C7NRE1 AIR synthase related protein domain protein n=4 ...   186   1e-45
UniRef50_B9LTA0 AIR synthase related protein domain protein n=4 ...   186   1e-45
UniRef50_C3N8T5 AIR synthase related protein domain protein n=11...   183   6e-45
UniRef50_C8WRZ3 Thiamine-monophosphate kinase n=2 Tax=Alicycloba...   181   3e-44
UniRef50_A6W2L4 Thiamine-monophosphate kinase n=2 Tax=Marinomona...   180   5e-44
UniRef50_C5A3X6 Thiamine monophosphate kinase (ThiL) n=4 Tax=The...   179   1e-43
UniRef50_Q0W120 Putative thiamine monophosphate kinase n=2 Tax=E...   178   2e-43
UniRef50_UPI0001BC315E hydrogenase expression/formation protein ...   176   7e-43
UniRef50_Q3ARA0 Thiamine-monophosphate kinase n=11 Tax=Chlorobia...   176   1e-42
UniRef50_A3HUE4 Hydrogenase expression/formation factor related ...   176   1e-42
UniRef50_B3QYZ8 Thiamine-monophosphate kinase n=1 Tax=Chloroherp...   176   1e-42
UniRef50_D2M233 Thiamine-monophosphate kinase n=1 Tax=Bacillus c...   175   2e-42
UniRef50_Q2RZV6 Thiamine-monophosphate kinase n=1 Tax=Salinibact...   174   4e-42
UniRef50_D1B5R8 AIR synthase related protein n=3 Tax=Synergistac...   173   7e-42
UniRef50_B0TDV9 Thiamine-monophosphate kinase n=1 Tax=Heliobacte...   171   3e-41
UniRef50_Q0ABQ2 Thiamine-monophosphate kinase n=3 Tax=Gammaprote...   167   4e-40
UniRef50_C4LAD9 Thiamine-monophosphate kinase n=1 Tax=Tolumonas ...   167   6e-40
UniRef50_Q2RJB8 Thiamine-monophosphate kinase n=1 Tax=Moorella t...   165   3e-39
UniRef50_A0L3Z7 Thiamine-monophosphate kinase n=1 Tax=Magnetococ...   163   7e-39
UniRef50_A1AS86 Thiamine-monophosphate kinase n=9 Tax=Desulfurom...   161   4e-38
UniRef50_C9RLV8 Thiamine-monophosphate kinase n=1 Tax=Fibrobacte...   156   1e-36
UniRef50_B8D469 AIR synthase related protein domain protein n=1 ...   152   1e-35
UniRef50_B7V7Q7 Thiamine monophosphate kinase n=11 Tax=Gammaprot...   152   2e-35
UniRef50_B7AVF9 Putative uncharacterized protein n=1 Tax=Bactero...   149   1e-34
UniRef50_B2UPF2 Thiamine-monophosphate kinase n=2 Tax=Verrucomic...   146   1e-33
UniRef50_Q9HHP1 Hydrogenase expression/formation protein n=1 Tax...   137   7e-31

Sequences not found previously or not previously below threshold:

UniRef50_B1CC54 Putative uncharacterized protein n=1 Tax=Anaerof...   199   1e-49
UniRef50_Q9V1N8 Probable thiamine-monophosphate kinase n=3 Tax=P...   180   6e-44
UniRef50_C0ZK37 Thiamin-monophosphate kinase n=1 Tax=Brevibacill...   172   1e-41
UniRef50_A4J8J0 Thiamine-monophosphate kinase n=1 Tax=Desulfotom...   170   5e-41
UniRef50_Q3II30 Thiamin-monophosphate kinase n=3 Tax=Alteromonad...   169   1e-40
UniRef50_O27447 Probable thiamine-monophosphate kinase n=1 Tax=M...   169   2e-40
UniRef50_D0SP02 Thiamine-monophosphate kinase n=1 Tax=Acinetobac...   168   2e-40
UniRef50_D0MD26 Thiamine-monophosphate kinase n=1 Tax=Rhodotherm...   167   4e-40
UniRef50_C4ZI96 Hydrogenase expression/formation protein n=1 Tax...   167   6e-40
UniRef50_Q46DN9 Thiamin-monophosphate kinase n=4 Tax=Methanosarc...   167   6e-40
UniRef50_C6LD50 Hydrogenase maturation factor n=1 Tax=Bryantella...   166   8e-40
UniRef50_A0M637 Thiamine-monophosphate kinase n=43 Tax=Bacteroid...   166   1e-39
UniRef50_B5FBG0 Thiamine-monophosphate kinase n=7 Tax=Vibrionace...   165   3e-39
UniRef50_C6X363 Thiamine-monophosphate kinase n=6 Tax=Bacteroide...   164   4e-39
UniRef50_B6YTL7 Thiamine monophosphate kinase n=2 Tax=Thermococc...   163   8e-39
UniRef50_Q57190 Thiamine-monophosphate kinase n=279 Tax=Gammapro...   163   8e-39
UniRef50_C6VU01 Thiamine-monophosphate kinase n=25 Tax=Bacteria ...   163   9e-39
UniRef50_B0VPT8 Thiamin-monophosphate kinase n=18 Tax=Moraxellac...   163   1e-38
UniRef50_D0KYD5 Thiamine-monophosphate kinase n=1 Tax=Halothioba...   161   2e-38
UniRef50_B3PBC5 Thiamine-monophosphate kinase n=1 Tax=Cellvibrio...   161   5e-38
UniRef50_Q15W96 Thiamine-monophosphate kinase n=2 Tax=Alteromona...   160   6e-38
UniRef50_D2RH67 Thiamine-monophosphate kinase n=1 Tax=Archaeoglo...   160   7e-38
UniRef50_B1I671 Thiamine-monophosphate kinase n=1 Tax=Candidatus...   160   9e-38
UniRef50_A8PLC8 Thiamine-monophosphate kinase n=2 Tax=Gammaprote...   159   1e-37
UniRef50_D2QDU8 Thiamine-monophosphate kinase n=1 Tax=Spirosoma ...   159   1e-37
UniRef50_Q8ESJ0 Thiamine monophosphate kinase n=1 Tax=Oceanobaci...   158   2e-37
UniRef50_A3DPV0 AIR synthase related protein domain protein n=1 ...   158   2e-37
UniRef50_Q0K6Z2 Thiamine monophosphate kinase n=114 Tax=Proteoba...   157   6e-37
UniRef50_Q3AE31 Thiamine-monophosphate kinase n=1 Tax=Carboxydot...   155   2e-36
UniRef50_O05514 Thiamine-monophosphate kinase n=5 Tax=Bacillus R...   155   2e-36
UniRef50_Q6AKX6 Related to thiamine-monophosphate kinase (ThiL) ...   155   2e-36
UniRef50_A7BRC9 Thiamine-monophosphate kinase n=1 Tax=Beggiatoa ...   153   6e-36
UniRef50_C8S8T5 Thiamine-monophosphate kinase n=1 Tax=Ferroglobu...   153   1e-35
UniRef50_C0GCU5 Thiamine-monophosphate kinase n=1 Tax=Dethiobact...   153   1e-35
UniRef50_A8VUM5 Beta-lactamase domain protein n=1 Tax=Bacillus s...   152   2e-35
UniRef50_C4Z424 Hydrogenase expression/formation protein HypE n=...   151   2e-35
UniRef50_D1J9H7 Thiamine-monophosphate kinase n=1 Tax=uncultured...   151   3e-35
UniRef50_Q1Q1A8 Similar to thiamine monophosphate kinase n=1 Tax...   151   3e-35
UniRef50_D2MI54 Thiamine-monophosphate kinase (Fragment) n=1 Tax...   151   4e-35
UniRef50_B4RQH6 Thiamine monophosphate kinase n=28 Tax=Neisseria...   151   4e-35
UniRef50_C5BS83 Thiamine-phosphate kinase n=1 Tax=Teredinibacter...   150   6e-35
UniRef50_Q5FH10 Thiamine-monophosphate kinase n=4 Tax=canis grou...   150   8e-35
UniRef50_D1R9A7 Putative uncharacterized protein n=1 Tax=Parachl...   150   8e-35
UniRef50_Q2JTF1 Thiamine-monophosphate kinase n=11 Tax=Cyanobact...   150   8e-35
UniRef50_B4U7Q4 Thiamine-monophosphate kinase n=3 Tax=Aquificace...   150   8e-35
UniRef50_A4SVD0 Thiamine-monophosphate kinase n=1 Tax=Polynucleo...   150   8e-35
UniRef50_Q8K9A5 Thiamine-monophosphate kinase n=4 Tax=Buchnera a...   150   9e-35
UniRef50_B0MTR2 Putative uncharacterized protein n=1 Tax=Alistip...   150   1e-34
UniRef50_A0LIX8 Thiamine-monophosphate kinase n=1 Tax=Syntrophob...   149   1e-34
UniRef50_C8R1R1 Thiamine-monophosphate kinase n=1 Tax=Desulfuriv...   149   1e-34
UniRef50_Q5QVE6 Thiamine monophosphate kinase n=2 Tax=Idiomarina...   148   2e-34
UniRef50_Q5FNA0 Thiamin-monophosphate kinase n=1 Tax=Gluconobact...   148   2e-34
UniRef50_B9XDK5 Thiamine-monophosphate kinase n=1 Tax=bacterium ...   148   2e-34
UniRef50_D1A2J3 AIR synthase related protein n=1 Tax=Thermomonos...   148   3e-34
UniRef50_D1C275 Thiamine-monophosphate kinase n=1 Tax=Sphaerobac...   148   3e-34
UniRef50_Q1IHF6 Thiamine-monophosphate kinase n=1 Tax=Candidatus...   147   5e-34
UniRef50_A0B852 Thiamine-monophosphate kinase n=1 Tax=Methanosae...   147   5e-34
UniRef50_B5Y8K3 Hydrogenase expression/formation protein HypE, p...   147   5e-34
UniRef50_B9ZS01 Thiamine-monophosphate kinase n=1 Tax=Thioalkali...   147   5e-34
UniRef50_D1BMW6 Thiamine-monophosphate kinase n=3 Tax=Veillonell...   147   7e-34
UniRef50_A6CFS7 Thiamine-monophosphate kinase n=1 Tax=Planctomyc...   146   7e-34
UniRef50_Q1YU39 Thiamine-monophosphate kinase n=1 Tax=gamma prot...   146   9e-34
UniRef50_C3K2R7 Thiamine-monophosphate kinase n=3 Tax=Gammaprote...   146   1e-33
UniRef50_Q607V1 Thiamine-monophosphate kinase n=1 Tax=Methylococ...   146   1e-33
UniRef50_B4WXS9 Thiamine-monophosphate kinase n=1 Tax=Alcanivora...   143   6e-33
UniRef50_Q31FT3 Thiamine-monophosphate kinase n=1 Tax=Thiomicros...   143   7e-33
UniRef50_B5JUN1 Thiamine-monophosphate kinase n=1 Tax=gamma prot...   143   8e-33
UniRef50_Q65TX9 ThiL protein n=4 Tax=Pasteurellaceae RepID=Q65TX...   143   9e-33
UniRef50_B4D453 Thiamine-monophosphate kinase n=1 Tax=Chthonioba...   143   1e-32
UniRef50_A5Z7T1 Putative uncharacterized protein n=1 Tax=Eubacte...   143   1e-32
UniRef50_B0KL72 Thiamine-monophosphate kinase n=13 Tax=Pseudomon...   143   1e-32
UniRef50_D1CF57 Thiamine-monophosphate kinase n=1 Tax=Thermobacu...   143   1e-32
UniRef50_Q5WJP9 Thiamine-monophosphate kinase n=3 Tax=Bacillus R...   143   1e-32
UniRef50_A1AW74 Thiamine-monophosphate kinase n=2 Tax=sulfur-oxi...   142   2e-32
UniRef50_C0QQC1 Thiamine-monophosphate kinase n=2 Tax=Hydrogenot...   142   2e-32
UniRef50_A1WVF9 Thiamine-monophosphate kinase n=2 Tax=Ectothiorh...   141   2e-32
UniRef50_B7JUY6 Thiamine-monophosphate kinase n=4 Tax=Cyanobacte...   141   3e-32
UniRef50_A1SWW7 Thiamine-monophosphate kinase n=2 Tax=Psychromon...   141   3e-32
UniRef50_B9KXI5 Thiamine-monophosphate kinase n=1 Tax=Thermomicr...   141   5e-32
UniRef50_Q2S9S1 Thiamine-monophosphate kinase n=1 Tax=Hahella ch...   141   5e-32
UniRef50_Q21F21 Thiamine-monophosphate kinase n=1 Tax=Saccharoph...   141   5e-32
UniRef50_C9YEU1 Thiamine-monophosphate kinase n=1 Tax=Curvibacte...   140   6e-32
UniRef50_A6FBC8 Thiamine monophosphate kinase n=1 Tax=Moritella ...   140   6e-32
UniRef50_C6V4B8 Thiamine-monophosphate kinase n=2 Tax=Neorickett...   140   7e-32
UniRef50_Q3A8K1 Thiamine-monophosphate kinase n=2 Tax=Desulfurom...   140   8e-32
UniRef50_Q1N2P0 Thiamine monophosphate kinase n=1 Tax=Bermanella...   139   9e-32
UniRef50_B2V6K1 Thiamine-monophosphate kinase n=3 Tax=Aquificale...   139   1e-31
UniRef50_C1ZKV1 Thiamine-monophosphate kinase n=1 Tax=Planctomyc...   139   1e-31
UniRef50_C9LRA0 Thiamine-phosphate kinase n=1 Tax=Dialister invi...   139   1e-31
UniRef50_C6CVI9 Thiamine-monophosphate kinase n=1 Tax=Paenibacil...   139   2e-31
UniRef50_UPI00003C83B8 thiamine monophosphate kinase n=1 Tax=Fer...   138   2e-31
UniRef50_C6QHP2 Thiamine-monophosphate kinase n=1 Tax=Hyphomicro...   138   3e-31
UniRef50_D1AS58 Thiamin-monophosphate kinase n=5 Tax=Anaplasma R...   138   3e-31
UniRef50_Q1NMW0 Thiamine-monophosphate kinase n=2 Tax=delta prot...   138   3e-31
UniRef50_B8KML1 Putative thiamine-monophosphate kinase n=1 Tax=g...   138   4e-31
UniRef50_B4UJS8 Thiamine-monophosphate kinase n=7 Tax=Cystobacte...   138   4e-31
UniRef50_Q0BTF2 Thiamine-monophosphate kinase n=2 Tax=Acetobacte...   137   6e-31
UniRef50_UPI00016C3B48 thiamine-monophosphate kinase n=1 Tax=Gem...   137   7e-31
UniRef50_Q7NG75 Thiamine-monophosphate kinase n=1 Tax=Gloeobacte...   136   9e-31
UniRef50_C7R8N3 Thiamine-monophosphate kinase n=1 Tax=Kangiella ...   136   9e-31
UniRef50_B1L7H6 Thiamine-monophosphate kinase n=1 Tax=Candidatus...   136   1e-30
UniRef50_A3VRR7 Thiamine-monophosphate kinase n=1 Tax=Parvularcu...   136   1e-30
UniRef50_Q1QUD0 Thiamine-monophosphate kinase n=1 Tax=Chromohalo...   136   1e-30
UniRef50_D1PUY6 Thiamine monophosphate kinase n=6 Tax=Prevotella...   135   2e-30
UniRef50_Q6MP56 Thiamine-monophosphate kinase n=1 Tax=Bdellovibr...   135   2e-30
UniRef50_A5UMR0 Thiamine monphosphate kinase, ThiL n=3 Tax=Metha...   134   3e-30
UniRef50_Q8TXQ3 Thiamine monophosphate kinase n=1 Tax=Methanopyr...   134   3e-30
UniRef50_UPI0001C16452 Thiamine-monophosphate kinase n=2 Tax=Nos...   134   4e-30
UniRef50_Q3ZZF3 Thiamine-monophosphate kinase n=5 Tax=Dehalococc...   134   4e-30
UniRef50_C0B9V8 Putative uncharacterized protein n=1 Tax=Coproco...   134   4e-30
UniRef50_D1VW68 Thiamine-phosphate kinase n=2 Tax=Prevotella Rep...   134   4e-30
UniRef50_D2LH51 Thiamine-monophosphate kinase n=1 Tax=Rhodomicro...   134   5e-30
UniRef50_B6BWK7 Thiamine-monophosphate kinase n=1 Tax=beta prote...   134   5e-30
UniRef50_A0NME7 Thiamine-monophosphate kinase n=2 Tax=Labrenzia ...   134   6e-30
UniRef50_A2BKY5 Predicted thiamine-monophosphate kinase n=1 Tax=...   133   1e-29
UniRef50_C7JHE3 Thiamine monophosphate kinase n=8 Tax=Acetobacte...   133   1e-29
UniRef50_A1K2S2 Thiamine-phosphate kinase n=9 Tax=cellular organ...   132   1e-29
UniRef50_Q2GJY6 Thiamine-monophosphate kinase n=1 Tax=Anaplasma ...   132   2e-29
UniRef50_B5EQ44 Thiamine-monophosphate kinase n=3 Tax=Acidithiob...   132   2e-29
UniRef50_B3DWZ3 Thiamine monophosphate kinase n=1 Tax=Methylacid...   132   2e-29
UniRef50_C6HZ14 Thiamine-monophosphate kinase n=1 Tax=Leptospiri...   131   3e-29
UniRef50_C0EUP9 Putative uncharacterized protein n=1 Tax=Eubacte...   131   3e-29
UniRef50_B2SNW6 Thiamine-monophosphate kinase n=21 Tax=Gammaprot...   131   3e-29
UniRef50_C0GR51 Thiamine-monophosphate kinase n=1 Tax=Desulfonat...   131   4e-29

>UniRef50_A6VPG0 Hydrogenase expression/formation protein HypE n=16
           Tax=Gammaproteobacteria RepID=A6VPG0_ACTSZ
          Length = 337

 Score =  421 bits (1084), Expect = e-116,   Method: Composition-based stats.
 Identities = 226/335 (67%), Positives = 269/335 (80%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I +AHG+GG AMQ+LI   F EAF NP L + EDQAR+ L +L   G +LAFSTDS+V
Sbjct: 3   DFITMAHGNGGAAMQKLIREYFFEAFNNPILVQGEDQARIPLNELTKCGQKLAFSTDSFV 62

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           IDP+FFPGGNIGKLA+CGTANDVAVSGA+P+YLSCGFILEEGLP+  LK V+ +MAET R
Sbjct: 63  IDPIFFPGGNIGKLAVCGTANDVAVSGAVPKYLSCGFILEEGLPLSELKTVIQAMAETCR 122

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            AGI +VTGDTKVVQ+GAVDK+FINT+G+G IP  + WGA  +  GD ++VSGT+GDHGA
Sbjct: 123 KAGIQVVTGDTKVVQKGAVDKIFINTSGIGVIPDRLDWGAHRIEPGDQIIVSGTIGDHGA 182

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
           TILNLRE LG+  EL SDCAVLTPLI  LR I GVKA+RDATRGGVNAV+HE+  ACG G
Sbjct: 183 TILNLRENLGIQSELQSDCAVLTPLIDLLRPIDGVKAVRDATRGGVNAVLHEYVQACGVG 242

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           + + EAALPV+  VRG+CE+LGL+ALNFANEGKLVI  +     ++L ALHSH LGK+AA
Sbjct: 243 MLIEEAALPVRSEVRGICEILGLEALNFANEGKLVIVAKPEKTAEILTALHSHELGKNAA 302

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG V E K VRLAG++G  R LDLP  EPLPRIC
Sbjct: 303 VIGTVTEDKKVRLAGIFGQTRLLDLPANEPLPRIC 337


>UniRef50_C1F4L5 Hydrogenase expression/formation protein HypE n=5 Tax=Bacteria
           RepID=C1F4L5_ACIC5
          Length = 374

 Score =  390 bits (1003), Expect = e-107,   Method: Composition-based stats.
 Identities = 157/343 (45%), Positives = 217/343 (63%), Gaps = 14/343 (4%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
           NI + HGSGG+   +LI+ +F++ F NP L   +DQA L++      G RLAF+TDS+V+
Sbjct: 37  NIVMGHGSGGKLSAELIDKIFVQRFRNPILDRMDDQAVLEIG-----GMRLAFTTDSFVV 91

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LA+ GT ND+A+ GA P YLS  FILEEGLP + L  VV SM + A A
Sbjct: 92  TPLFFPGGDIGHLAVNGTVNDLAMCGARPLYLSAAFILEEGLPTQDLARVVESMRDAANA 151

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A I +VTGDTKVV RG  DK+FI T G+G +       A     GD +++SG +GDHG T
Sbjct: 152 ANIQLVTGDTKVVNRGKGDKVFITTTGIGIVDRPTEMSADRAQPGDKVILSGFIGDHGIT 211

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLR-------DIPGVKALRDATRGGVNAVVHEFA 235
           IL+ RE L  + +L SDCA L  L++ +        +I G++ +RD TRGGV  V++E A
Sbjct: 212 ILSQREHLEFESDLKSDCAPLHSLVEAMLNEAEANGNIKGIRCMRDPTRGGVATVLNEIA 271

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
                G+ L E+++PV+ +VRG CE+LGLD L  ANEGKL+  V    A+Q++  +  HP
Sbjct: 272 RKSHVGMRLHESSIPVRESVRGACEVLGLDPLYVANEGKLLAVVAPQIADQLIVRMRKHP 331

Query: 296 LGKDAALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           LG ++ +IGE+  +    V +    G  R +D+   E +PRIC
Sbjct: 332 LGTESQIIGEITGQPRDMVLMKTSIGGTRVVDVLFGEQMPRIC 374


>UniRef50_C1DUF0 Hydrogenase expression/formation protein HypE n=10 Tax=Bacteria
           RepID=C1DUF0_SULAA
          Length = 332

 Score =  387 bits (994), Expect = e-106,   Method: Composition-based stats.
 Identities = 164/339 (48%), Positives = 221/339 (65%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I LAHG GG+  Q+LI  LF + F N  L   ED A L++        ++AF+TDS+
Sbjct: 1   MKQIMLAHGGGGEETQKLIKELFFKYFNNEILLSMEDSAVLNI------NSKVAFTTDSF 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            I P+FF GG+IGKLAI GT ND++V GA P YLSC FI+EEG P E L+ +V SMAE  
Sbjct: 55  TISPIFFSGGDIGKLAIAGTVNDLSVMGAKPLYLSCSFIIEEGFPFEDLEKIVKSMAEEL 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +  G  IVTGDTKVV RG VDK+FINT+G+G +       A  L+ GD ++VSGT+GDHG
Sbjct: 115 KKTGTLIVTGDTKVVPRGFVDKIFINTSGLGKVVYE-GVSAHNLSEGDSIIVSGTVGDHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACG 239
             I+  RE + +  +L+SDC  +  L++ L +    +KA+RD TRGG++AV++E+A +  
Sbjct: 174 VCIMAQREGIDMQTDLISDCDSVWTLVEDLIKGNVKIKAMRDPTRGGLSAVLNEWAESSN 233

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             IE+ E  +PVKP V+G+CELLGL+    ANEG++V+AV +   E+ L  L  +PLGKD
Sbjct: 234 VEIEVLEEKIPVKPQVQGLCELLGLEPYVLANEGRIVVAVSKEDTEKALEILRKNPLGKD 293

Query: 300 AALIGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A LIG+V    +K V L   YG  R ++ P  E LPRIC
Sbjct: 294 AQLIGKVNSKGKKRVILKTSYGSLRIMEPPAGEILPRIC 332


>UniRef50_C6PIR8 Hydrogenase expression/formation protein HypE n=3 Tax=Bacteria
           RepID=C6PIR8_9THEO
          Length = 329

 Score =  385 bits (990), Expect = e-105,   Method: Composition-based stats.
 Identities = 160/337 (47%), Positives = 220/337 (65%), Gaps = 9/337 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ + L+HG GG  M+ LI  +F +AF N ++   ED A L           + F+TDS+
Sbjct: 1   MDKVLLSHGGGGTMMESLIEEVFSKAFDNEYIKGMEDAALL--------FGNITFTTDSF 52

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IG+LA+CGT ND ++ GA P YL+  FI+EEG PME LK +V SMAETA
Sbjct: 53  TVKPIFFPGGDIGRLAVCGTVNDASMRGAKPLYLTSAFIIEEGYPMEDLKKIVKSMAETA 112

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             AG+ IV GDTKVV++G VD +FINT+G+G +  N+    +    GDV+LVSGT+GDHG
Sbjct: 113 EEAGVKIVAGDTKVVEKGGVDGVFINTSGIGVVYENVDVSIKNAKPGDVVLVSGTIGDHG 172

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDI-PGVKALRDATRGGVNAVVHEFAAACG 239
             I++ RE+L  D  ++SD + L  LI+ L  +   VK LRD TRGGV  V++E +   G
Sbjct: 173 MAIMSAREELQFDPPILSDVSPLNKLIEKLMTLGKAVKVLRDPTRGGVAEVLYEISKMSG 232

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GI++ E  LPVK +V+  CE++G D L+ ANEGKL+  ++R  AE+ L  + S   GKD
Sbjct: 233 VGIKIYEDKLPVKDSVKHACEMMGFDFLHLANEGKLITVIDRKYAEEALEIMKSDKYGKD 292

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGEV + K V +  +YG  R +D P  E LPRIC
Sbjct: 293 AAIIGEVNDSKLVTINTIYGTSRIVDRPIGELLPRIC 329


>UniRef50_P31906 Hydrogenase expression/formation protein hypE n=170 Tax=Bacteria
           RepID=HYPE_BRAJA
          Length = 346

 Score =  376 bits (966), Expect = e-103,   Method: Composition-based stats.
 Identities = 167/337 (49%), Positives = 215/337 (63%), Gaps = 9/337 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           + L+HGSGG+AM QLI+ LF EAF N WLA   DQ+  D+        R+  +TD YV+ 
Sbjct: 15  VDLSHGSGGRAMAQLISGLFHEAFGNEWLARGNDQSAFDVRA-----GRMVMTTDGYVVS 69

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGGNIG LA+ GT ND+A++GA P YLS  FI+EEG     LK +  SM   AR A
Sbjct: 70  PLFFPGGNIGSLAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFADLKLIAESMGAAAREA 129

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            + I+TGDTKVV+RG  D LFI+TAG+G +P  +   A+    GD +L+SGTLGDHG  I
Sbjct: 130 DVHIITGDTKVVERGKADGLFISTAGVGVVPDGLDLSAEKARVGDRVLISGTLGDHGVAI 189

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIP--GVKALRDATRGGVNAVVHEFAAACGCG 241
           ++ R+ L  + E+VSD A L  L+  +      G++ +RD TRGG+ A ++E A     G
Sbjct: 190 MSKRQNLAFETEIVSDSASLHDLVARMVQAGGRGIRLMRDPTRGGLAATLNEIAQQSNLG 249

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             L E A+PVKP V   CELLGLD L+ ANEGKLV  V   AA  VLAA+ +HPLG+DAA
Sbjct: 250 FHLLEEAIPVKPGVAAACELLGLDPLHVANEGKLVAIVAPEAAGAVLAAMRAHPLGRDAA 309

Query: 302 LIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            IGE V  +   V++A  +G  R +D    E LPRIC
Sbjct: 310 DIGEAVADDHHFVQMATSFGGGRIVDWLSGEQLPRIC 346


>UniRef50_P40599 Hydrogenase expression/formation protein hypE n=110 Tax=Bacteria
           RepID=HYPE_RHILV
          Length = 350

 Score =  375 bits (963), Expect = e-102,   Method: Composition-based stats.
 Identities = 156/338 (46%), Positives = 212/338 (62%), Gaps = 9/338 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            I L+HG+GG+AM QLI  +F +AF N WL    DQ+          G R+  +TD YV+
Sbjct: 18  RIDLSHGAGGRAMGQLIEGIFHKAFDNDWLRAGNDQSA-----FSVPGGRMVMTTDGYVV 72

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGGNIG LA+ GT ND+A++GA+P YLS  FI+EEG P+  L+ +  SM   +R 
Sbjct: 73  SPLFFPGGNIGTLAVHGTINDIAMAGAVPLYLSASFIIEEGFPLVDLERIADSMGAASRE 132

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ I+TGDTKVV+RG  D +FI+TAG+G  P  +   +     GD +++SG++GDHG  
Sbjct: 133 AGVPIITGDTKVVERGKADGVFISTAGIGMAPDGLDLRSDAARPGDAVIISGSIGDHGVA 192

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVK--ALRDATRGGVNAVVHEFAAACGC 240
           +++ RE L  D ++VSD A L  L+  +    G     +RD TRGG+ A ++E A+    
Sbjct: 193 VMSKRENLEFDTDIVSDSAALHGLVADMVAAGGAHIRLMRDPTRGGIAATLNEIASQSRV 252

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G  + E A+P+KP V   CE LGLD LN ANEGKLV  V    A+ VLAA+H+HPLG +A
Sbjct: 253 GFRIDEEAIPMKPEVAAACEFLGLDPLNVANEGKLVAVVAPEGADAVLAAIHAHPLGAEA 312

Query: 301 ALIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           ALIG VV  +   V++   +G  R +D    E LPRIC
Sbjct: 313 ALIGHVVADDNYFVQMVTSFGGGRIVDWLSGEQLPRIC 350


>UniRef50_B8D1S4 Hydrogenase expression/formation protein HypE n=3 Tax=Bacteria
           RepID=B8D1S4_HALOH
          Length = 334

 Score =  371 bits (953), Expect = e-101,   Method: Composition-based stats.
 Identities = 144/339 (42%), Positives = 220/339 (64%), Gaps = 8/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           MN I LAHG+GG+ M+ LI++LF++   N  + +++D + +   + V        STD++
Sbjct: 1   MNTISLAHGNGGKMMEDLIDNLFLKYLNNDIINKKDDASPVPEIKGVP-----VISTDTF 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+DP+FFPGGNIGKL+ICGT ND+AV+GAIP YL+ GFILEEGLP++ L+ ++ SMAE +
Sbjct: 56  VVDPIFFPGGNIGKLSICGTVNDLAVTGAIPLYLTVGFILEEGLPIKHLEKIIISMAEVS 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           R A + IV GDTKVV+RG  DK+FINT G+G I   +    + +  GD ++++G++ +HG
Sbjct: 116 REANVKIVAGDTKVVERGKGDKIFINTTGVGMIGDKLKLSDENIKLGDKVIINGSIAEHG 175

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
             IL  R Q+     + SDC  L+ LI   L +  G+K +RD TRGG+  V++E A    
Sbjct: 176 LAILMERNQMDFSTSIKSDCCTLSDLIVTLLSETNGIKFMRDPTRGGMATVLNEIATRYN 235

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GIE+ E  +P+   ++ +C++LGLD L  ANEGK++I  +R  +E+++  +  HP G++
Sbjct: 236 VGIEIEEEKVPLGDEIKSLCKILGLDPLYLANEGKVLIIADREKSEKIVDIMRRHPYGRN 295

Query: 300 AALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +++IG +V+     V L    G KR +     + LPRIC
Sbjct: 296 SSIIGTIVDNNDQQVYLKTRIGGKRIITKLMHDMLPRIC 334


>UniRef50_A4XJQ3 Hydrogenase expression/formation protein HypE n=9 Tax=Clostridia
           RepID=A4XJQ3_CALS8
          Length = 336

 Score =  370 bits (951), Expect = e-101,   Method: Composition-based stats.
 Identities = 132/339 (38%), Positives = 192/339 (56%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  IQ  HG+GG+   +LIN LF   F +  L   +D +  DLA       ++  +TDS+
Sbjct: 5   MKFIQKEHGNGGKQTYELINELFKPIFDSEILKRGDDSSIFDLAS-----KKIGVTTDSF 59

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FF GG+IGKL++CGT ND+AVSG +P+Y++  FI+EEG P+  L+ +V SM E A
Sbjct: 60  VVKPYFFKGGDIGKLSVCGTVNDLAVSGLVPKYITASFIIEEGFPIVDLQKIVKSMKEYA 119

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH-WGAQTLTAGDVLLVSGTLGDH 179
             AG+ IV GDTKVV++G+ D +FINT G G           + +  G V+LVSG +G H
Sbjct: 120 DIAGVEIVAGDTKVVEKGSCDGIFINTTGFGVCEKEEKFPSIEKIKGGQVILVSGDIGRH 179

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
           GA I +   + G + ++ SDCA L  +I  L +   +  ++D TRGG+   ++E A    
Sbjct: 180 GACIYSHNSEFGFEEKIESDCAPLNRVINELLENVEICYMKDLTRGGLATALNEIAQKAN 239

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I + E  +PV   V+ +C++LGLD    A EG+ V  V R   ++ L  L      K+
Sbjct: 240 VAIYVEEDKVPVSNEVKALCDILGLDWYYLACEGRFVAIVNRKNEQRALEILRK--YNKE 297

Query: 300 AALIGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A  IG +   E   V L   +G  R LD+ + + LPRIC
Sbjct: 298 ACEIGWIEDTEENRVYLRTSFGGTRILDMLYYDMLPRIC 336


>UniRef50_Q0HUQ3 Hydrogenase expression/formation protein HypE n=38 Tax=Bacteria
           RepID=Q0HUQ3_SHESR
          Length = 339

 Score =  367 bits (942), Expect = e-100,   Method: Composition-based stats.
 Identities = 155/336 (46%), Positives = 210/336 (62%), Gaps = 10/336 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           IQL+HG GG+ M +LI  LF   F NP L  +ED A+L+L          AF+TDS+ + 
Sbjct: 11  IQLSHGGGGKEMNKLIRELFFAEFDNPILRSEEDAAKLELQ------GATAFTTDSFTVS 64

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFF GG+IGKLAI GT ND+A+ GA P+YLSC  I+EEG  +  L  +V SMA+  + +
Sbjct: 65  PLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKELKQS 124

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G  IV GDTKVV +G  D LFINT+G+G I    +  A  +  GD ++VS  +G HGA I
Sbjct: 125 GARIVCGDTKVVPKGCADGLFINTSGVGRILRP-NISAANVAPGDAIIVSRDVGCHGAAI 183

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDI-PGVKALRDATRGGVNAVVHEFAAACGCGI 242
           L  RE L L+  L SDCA L P+++ L      + A+RDATRGG++AV++E+AAA   GI
Sbjct: 184 LMAREGLTLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAAAANVGI 243

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            ++EA++PV   V+G+CEL G +A++ ANEG  ++AV  + A   L  +      + AA+
Sbjct: 244 TVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQAAI 303

Query: 303 IGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           IG V +     V L   +  KR LDLP  E LPRIC
Sbjct: 304 IGTVSDELPGKVILRTPWNTKRYLDLPQGELLPRIC 339


>UniRef50_B2TM78 Hydrogenase expression/formation protein HypE n=4 Tax=Clostridium
           RepID=B2TM78_CLOBB
          Length = 337

 Score =  366 bits (940), Expect = e-100,   Method: Composition-based stats.
 Identities = 145/342 (42%), Positives = 214/342 (62%), Gaps = 11/342 (3%)

Query: 1   MNN--IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTD 58
           MNN  I L+HGSGG    +LI+ +F   F N  L +Q D   L+         ++A + D
Sbjct: 1   MNNKIITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLN-----EIKGKIATTID 55

Query: 59  SYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
            +V+DP+FF GG+IGKL++CGT ND+AVSGA P Y++C FI+EEG   ++L+ +V SMA+
Sbjct: 56  GFVVDPIFFKGGDIGKLSLCGTINDLAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAK 115

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHW-GAQTLTAGDVLLVSGTLG 177
           TA+ + + IV GDTKVV++G   K++I+T G+G      +      + +GD +++SGT+G
Sbjct: 116 TAKESNVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNILNVNNIKSGDKIILSGTIG 175

Query: 178 DHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAA 236
           +HG  I+N RE L +D E+ SDCA L  L + + +    V+ +RD TRGG+   ++E + 
Sbjct: 176 EHGMCIVNKRENLNIDSEIKSDCAPLNSLCEIILNTSNNVRIMRDPTRGGIANTLNELSR 235

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
           +    + + E  +P+   VR   ELLG+  L  ANEGKL+  V+   AE VL+A+ +HPL
Sbjct: 236 SSLKSMMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPL 295

Query: 297 GKDAALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           GKDAA+IGEV+E     V + GL G  + L +   E LPRIC
Sbjct: 296 GKDAAIIGEVIEENKGAVYIKGLLGSTKVLQMSQGELLPRIC 337


>UniRef50_B0TWC9 Hydrogenase expression/formation protein HypE n=3 Tax=Francisella
           philomiragia RepID=B0TWC9_FRAP2
          Length = 341

 Score =  362 bits (929), Expect = 1e-98,   Method: Composition-based stats.
 Identities = 154/336 (45%), Positives = 211/336 (62%), Gaps = 9/336 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           + LA G+GG+AM  LI  +  ++F + +LA+ EDQA L          ++A +TDSYVI 
Sbjct: 12  VDLAMGAGGKAMHHLIEQMIKKSFDSQYLAQAEDQAILP-----QINGKIAMTTDSYVIT 66

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P FF GGNIG LAI GT ND+ V GA P Y+S G ILEEGLP+  LK ++ SMAETA+ A
Sbjct: 67  PYFFRGGNIGSLAIHGTVNDLVVGGAKPLYISVGLILEEGLPLRDLKVILDSMAETAKKA 126

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            + IVTGDTKVV++G  D +FINT G+G I  +      TL  GD ++++GTLGDHG  +
Sbjct: 127 NVQIVTGDTKVVEKGKGDGIFINTTGVGVIRDDF-VTRDTLEDGDEIIINGTLGDHGVAV 185

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGI 242
           ++ R  L  + ++VSD   L  L+  + D    +K +RD TRGGV A ++E+A      I
Sbjct: 186 MSQRAGLDFECQIVSDATSLDSLVDAIYDNKCQIKTMRDPTRGGVGATLNEWANQYNVAI 245

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+ EA LP+   V+  CELLGLD L  ANEGK++IA + +  ++VL  L  HPLG++A +
Sbjct: 246 EIDEANLPISTEVQSACELLGLDPLYIANEGKVLIACKPSQTQKVLDCLRGHPLGENAQV 305

Query: 303 IGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           I  V   E+  V +   +G KR +D    E LPRIC
Sbjct: 306 IATVRKSEQSQVFMKTTFGGKRRVDWLSGEQLPRIC 341


>UniRef50_C6PPZ0 Hydrogenase expression/formation protein HypE n=6 Tax=Clostridiales
           RepID=C6PPZ0_9CLOT
          Length = 334

 Score =  361 bits (927), Expect = 2e-98,   Method: Composition-based stats.
 Identities = 145/340 (42%), Positives = 204/340 (60%), Gaps = 10/340 (2%)

Query: 1   MNNI-QLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDS 59
           M+ I  LAHG+GG+   +LI+ +F   F+NP L         D A L  +G +LAF+TD 
Sbjct: 1   MDKIVTLAHGAGGRQTSELIDQVFKAHFSNPDLTAD------DAAVLNVKGGKLAFTTDG 54

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           +++ P  FPGGNIGKL+ICGT ND++  GA P YLSC F++EEG PME L+ +  +M +T
Sbjct: 55  FIVSPSEFPGGNIGKLSICGTVNDLSCMGAKPLYLSCAFVIEEGFPMEKLEKIAAAMEKT 114

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
           A  AG+ IV GDTKV  +G VD +FI T G+G I   ++        GD ++V+G +G H
Sbjct: 115 ADEAGVKIVAGDTKVAGKGQVDGVFITTTGIGQIIDGVNTSGFNAKPGDAIIVTGDIGRH 174

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAAC 238
           G T+L  R + G++ ++VSDCA L   ++ + D    +  +RDATRGGV  V++E A   
Sbjct: 175 GCTVLLARNEFGIEADVVSDCAPLWGTVKAMLDESKDIHVIRDATRGGVGTVLYEIAEQS 234

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI L   ++PV   V+GVC +LGL+ L  A EG+LVI   +  A +++  LH     K
Sbjct: 235 KVGIRLDSKSIPVADGVKGVCGMLGLEPLYLACEGRLVIFAPKEVAPKLVDTLHEGKYSK 294

Query: 299 DAALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           DAA+IGEV +     V +    G +  L  P  E LPRIC
Sbjct: 295 DAAIIGEVTQDMAGRVIVKTEIGAETLLPPPGGELLPRIC 334


>UniRef50_B7JZ80 Hydrogenase expression/formation protein HypE n=17 Tax=Bacteria
           RepID=B7JZ80_CYAP8
          Length = 348

 Score =  360 bits (925), Expect = 3e-98,   Method: Composition-based stats.
 Identities = 155/339 (45%), Positives = 206/339 (60%), Gaps = 12/339 (3%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG GG+ MQQL+  +F  AF         D A L L       +++AF+TDSYVI
Sbjct: 17  QVLLAHGGGGKLMQQLLEKMFFPAFKTTHNIPPHDSAVLSLNT-----NKIAFTTDSYVI 71

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LAI GT ND+A+SGA P YLS GFILEEGLPMETL  VV S+ + A+ 
Sbjct: 72  HPLFFPGGDIGSLAINGTVNDLAMSGARPLYLSVGFILEEGLPMETLWRVVQSLQKAAQI 131

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A + I+TGDTKVV  G  D +FINTAG+G +  N     Q++  GD +L+SG LG HG  
Sbjct: 132 AEVQIITGDTKVVDHGKGDGIFINTAGVGIVEHNQVIAPQSVQPGDAILISGDLGRHGIA 191

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCG 241
           I+ +RE L  +  + SDCA L+ L+  + D    +  LRD TRGG+ + ++E A   G  
Sbjct: 192 IMAVREGLEFETAIESDCAPLSTLVLEMLDAGVEIHCLRDLTRGGLASALNEIATGAGVT 251

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           +++ E A+PV   V+G CE+LG D L  ANEG+LV  + +N+  + L  L SH   + A+
Sbjct: 252 LKVQETAIPVAEDVQGACEILGFDPLYVANEGRLVAFIPQNSVSRALEILRSHH--QQAS 309

Query: 302 LIGEVVERKG----VRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG+V         V L    G  R LD+   E LPRIC
Sbjct: 310 IIGQVTGTGTGMGLVTLESRIGASRILDMLSGEQLPRIC 348


>UniRef50_C5ZXL6 Hydrogenase expression/formation protein HypE n=4 Tax=Helicobacter
           RepID=C5ZXL6_9HELI
          Length = 340

 Score =  360 bits (924), Expect = 5e-98,   Method: Composition-based stats.
 Identities = 145/337 (43%), Positives = 207/337 (61%), Gaps = 6/337 (1%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L+HGSGG   Q+LI+ LF        +   ED    +L  +     + A STD Y I 
Sbjct: 6   ITLSHGSGGVESQKLISELFYPFLEGCVIGNGEDAGIGELDSISQ--GKFAISTDGYTIS 63

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGG+IGKL+ICG+ NDVA+ GA P+YLS  F++EEG  ++ LK ++ S  +T +A+
Sbjct: 64  PLFFPGGDIGKLSICGSCNDVAMMGAKPKYLSASFMIEEGFLIDDLKKILDSFGKTLKAS 123

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGA-IPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           G  +++GDTKV+ +G +DK+FI T   G  +  ++   A  +     +LVSG +G+HGA 
Sbjct: 124 GAKLLSGDTKVLPKGTLDKIFITTTAFGEFLYPHLQISAFNIPQDCCILVSGEIGNHGAV 183

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
           + + RE++ L   L SDC +L P ++ L ++   + ALRDATRGG+ +V++E+A A   G
Sbjct: 184 VYSKREEISLQSNLESDCQLLYPSLEELFKNNLSIYALRDATRGGIASVLNEWANASHIG 243

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IE+ E  LP+K  VRG+CELLG +A N ANEG  V+A+ +  +++ L  L   P GK+A 
Sbjct: 244 IEIEEETLPIKDEVRGICELLGFEAWNLANEGMCVLAIAKEDSKKALEILKRTPAGKNAT 303

Query: 302 LIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG         V L   YG KR LD P  E LPRIC
Sbjct: 304 IIGYTTSTNLNKVVLKTAYGAKRFLDYPSGELLPRIC 340


>UniRef50_B0TCN4 Hydrogenase expression/formation protein hype n=6 Tax=Firmicutes
           RepID=B0TCN4_HELMI
          Length = 360

 Score =  358 bits (918), Expect = 2e-97,   Method: Composition-based stats.
 Identities = 159/360 (44%), Positives = 208/360 (57%), Gaps = 32/360 (8%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I LAHG GG    +L+  +F+  F +P L +  D A L L +      RLA +TD++V+ 
Sbjct: 6   ILLAHGDGGALTHRLVQEIFLRHFDHPALRDLTDAALLHLPE-----GRLAMTTDTFVVK 60

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGG+IGKLA+ GT ND+AVSGA P YL+  FILEEG P+  L+ VV S+A TAR A
Sbjct: 61  PLFFPGGDIGKLAVAGTVNDLAVSGARPLYLTAAFILEEGFPLADLEQVVASLARTAREA 120

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G+A+V GDTKVV+RG  D ++INT G G +PA    G   +  GD ++V+GT+GDHG  I
Sbjct: 121 GVAVVAGDTKVVERGCGDGVYINTTGAGVVPAGRDLGYHRIMPGDAVIVNGTIGDHGLAI 180

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRD--IPGVKALRDATRGGVNAVVHEFAAACGCG 241
           L+ R  +  D  + SDCA +  L   L +     V+ +RD TRGGV   ++E A + G  
Sbjct: 181 LSKRAGIEFDTPVESDCAPMNGLTDMLLERFAEAVRFMRDPTRGGVATTLNEVAQSTGLN 240

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           I L E ALPV+  V+G  ELLGLD L  ANEGK++I     A E++L  L  HPLG +AA
Sbjct: 241 IILEEQALPVREEVQGAAELLGLDPLYLANEGKVLIVAAPEAVEEILTTLRRHPLGLNAA 300

Query: 302 LIGEVVERKG-------------------------VRLAGLYGVKRTLDLPHAEPLPRIC 336
            IG V    G                         V L    G  R +D+   +PLPRIC
Sbjct: 301 AIGRVEAGTGVGRGPGQGAGQRTGQGSGQGAGRGRVFLRTPLGGHRIVDMLAGDPLPRIC 360


>UniRef50_D2ATM4 Hydrogenase maturation factor-like protein n=35 Tax=Bacteria
           RepID=D2ATM4_STRRD
          Length = 446

 Score =  358 bits (918), Expect = 2e-97,   Method: Composition-based stats.
 Identities = 168/340 (49%), Positives = 216/340 (63%), Gaps = 14/340 (4%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I LAHG+GG+A   LI ++F+EAF NP L   ED A +D          LAF+TDSYV
Sbjct: 116 DRITLAHGAGGKATHTLIEAVFLEAFRNPLLEPLEDGAVVDG---------LAFTTDSYV 166

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG+IG LA+ GT ND+A+ GA PRYLS  FI+EEG P+  L+ +  SMA  AR
Sbjct: 167 VTPLFFPGGDIGDLAVNGTVNDLAMCGARPRYLSAAFIVEEGFPVADLRRITASMAAAAR 226

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           AA + IVTGDTKVV+ G  D  +I T+G+G +   I   A     GDV++VSG +G+HG 
Sbjct: 227 AADVWIVTGDTKVVENGKADGCYITTSGVGTVERPIRLSAAAARPGDVVIVSGPIGEHGV 286

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VKALRDATRGGVNAVVHEFAAAC 238
           T++  R +L +  +L SD A L  L   L D  G   V+ LRDATRGGV  VV+E A A 
Sbjct: 287 TVMLARGELDIQADLTSDTAPLNTLTGRLLDACGDGQVRCLRDATRGGVATVVNEIAVAS 346

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
              + L E A+PV PAVRG CELLG+D L  A EG++V  V + +AE  LAAL SHPLG 
Sbjct: 347 KVAVVLEEDAIPVCPAVRGACELLGIDPLYVACEGRMVAVVAQRSAEAALAALRSHPLGS 406

Query: 299 DAALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           +AA+IG + +     V L   +G  R +DL   +PLPRIC
Sbjct: 407 EAAVIGRIGDDPPGLVLLKTSFGGTRIVDLLVGDPLPRIC 446


>UniRef50_A4CGN3 Hydrogenase expression/formation protein HypE n=2
           Tax=Flavobacteriaceae RepID=A4CGN3_9FLAO
          Length = 339

 Score =  357 bits (916), Expect = 3e-97,   Method: Composition-based stats.
 Identities = 144/339 (42%), Positives = 200/339 (58%), Gaps = 10/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I L HGSGG    +L++S     F N  L ++ D A L L        + AF+TDS+V
Sbjct: 7   DIITLGHGSGGLLTNKLLDSGVFHLFDNEHLQQRHDGAMLTL------EGKTAFTTDSFV 60

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           I P+FFP  NIG+LA+ GT ND+A+ GAIP+YLS  FILEEGL M     ++ S+   A 
Sbjct: 61  ISPIFFPDSNIGELAVNGTVNDLAMCGAIPQYLSLSFILEEGLKMTEFWEILVSIKSAAE 120

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            A I IVTGDTKVV+RG  DK+FINT G+G + A        +  GD ++VS ++  HG 
Sbjct: 121 QANIQIVTGDTKVVERGKGDKIFINTTGIGQLHAKADIAPSNVQPGDKIIVSDSIATHGV 180

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGV--KALRDATRGGVNAVVHEFAAACG 239
            I+++RE L  + EL SD   L+ ++  L D  GV    L+D TRGGV  V++E A    
Sbjct: 181 AIMSVREGLEFESELKSDTRGLSHMVSELLDTFGVDIHLLKDPTRGGVATVLNEIARDRN 240

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GIE+ +  LP++  V  +CE+LGLD L  ANEG  +  V+   +E+V+  L S   G +
Sbjct: 241 LGIEILQKDLPLQNEVSALCEILGLDPLYVANEGIFIAVVKDAISEKVVEKLQSMEYGAN 300

Query: 300 AALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A++IG+V E   K V L    G +R +++   E LPRIC
Sbjct: 301 ASIIGDVTENHPKQVVLKSAIGGRRIVNMLAGEQLPRIC 339


>UniRef50_D1BLS0 Hydrogenase expression/formation protein HypE n=4
           Tax=Veillonellaceae RepID=D1BLS0_VEIPT
          Length = 335

 Score =  356 bits (913), Expect = 9e-97,   Method: Composition-based stats.
 Identities = 155/340 (45%), Positives = 212/340 (62%), Gaps = 9/340 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  ++L HG+GG+   +L +   ++ F N  LA   D A     Q      R+AFSTDSY
Sbjct: 1   MERVRLVHGNGGRFSHELTDRFILKYFTNDLLAPLHDGA-----QFPVTAGRMAFSTDSY 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FFPGGNIGKLA+CGT ND+A++GAIP+YLSCG ILEEGL  E L  ++ +M+E A
Sbjct: 56  VVQPAFFPGGNIGKLAVCGTVNDLAMNGAIPQYLSCGLILEEGLAFEELDEILRTMSEMA 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +AA + IVTGDTKVV++G VDK++INTAG+G IP  I  G   + AG  +++SG +GDH 
Sbjct: 116 KAANVQIVTGDTKVVKKGEVDKIYINTAGIGMIPDGIDIGPHRVKAGLDIILSGAIGDHS 175

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAAC 238
             ++  R  L L   L +DCA L  ++Q + D  G  V  LRD TRGG+  V+ E A   
Sbjct: 176 IAVMGQRFGLDLSDSLTTDCAPLNKMVQAVLDKVGTQVALLRDPTRGGLGTVLKEIADQS 235

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI++ E A+P+   V+ VC +LG D L  ANEGK+V+ VE +   +VL  LHS   G 
Sbjct: 236 QVGIKVEETAIPIHEEVQSVCNILGYDPLYLANEGKVVLIVEPSITNEVLKILHSFKEGS 295

Query: 299 DAALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +A LIG+ +++    V L    G  R +DL   + +PRIC
Sbjct: 296 EAVLIGKTIDKNIGKVGLQTAIGGVRLIDLLGEDQVPRIC 335


>UniRef50_A8ZNR3 Hydrogenase expression/formation protein HypE n=17 Tax=Bacteria
           RepID=A8ZNR3_ACAM1
          Length = 362

 Score =  356 bits (913), Expect = 9e-97,   Method: Composition-based stats.
 Identities = 151/353 (42%), Positives = 202/353 (57%), Gaps = 26/353 (7%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG GG+ M QLI  +F   F +      ED+   D A L     RLA +TDSYV+
Sbjct: 17  QVLLAHGGGGKLMHQLIEQMFGRLFQS------EDRHHHDAAVLGVPPGRLALTTDSYVV 70

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LA+ GT ND+A++GA P YLS  FILEEGL M TL  VV SM + A  
Sbjct: 71  HPLFFPGGDIGSLAVYGTVNDLAMAGARPLYLSTSFILEEGLSMTTLWQVVQSMQQAAHQ 130

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A + IVTGDTKVV+RG  D +FINTAG+G I  +     Q++  GD+++++G LG HG  
Sbjct: 131 ADVQIVTGDTKVVERGKGDGVFINTAGVGIIEHHQTIHPQSIQPGDLVILNGDLGRHGMA 190

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGV--KALRDATRGGVNAVVHEFAAACGC 240
           +L  RE L  + E+ SD A L  ++  L    GV    +RD TRGG+ + ++E A A G 
Sbjct: 191 VLAEREGLEFESEIKSDSAPLNHVVLDL-FAHGVELHCMRDLTRGGLASALNEIALATGV 249

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS------- 293
            I L E  +P++  V+G CE+LG D L  ANEG+ +  V   + +  LA L++       
Sbjct: 250 AISLDETCIPIREDVQGACEILGFDPLYVANEGRFIAFVPPQSVDLALARLNAPLSFPLS 309

Query: 294 -----HPLGK---DAALIGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
                HP  +    A +IG+V       V L    GV+R +D    E LPRIC
Sbjct: 310 GQSDTHPQMRHQHPAQVIGQVTTTTSPRVTLTNRLGVERIVDFLSGEQLPRIC 362


>UniRef50_UPI0001C42969 hydrogenase expression/formation protein HypE n=1 Tax=Bacillus
           pseudofirmus OF4 RepID=UPI0001C42969
          Length = 334

 Score =  354 bits (910), Expect = 2e-96,   Method: Composition-based stats.
 Identities = 147/341 (43%), Positives = 209/341 (61%), Gaps = 13/341 (3%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           +  I LAHG GG+   QLI  +FM AF++      + + + D A    EG R+A +TDSY
Sbjct: 2   VQRISLAHGEGGELTHQLIQEVFMSAFSS------KKEIQHDSAVFPIEGKRIAVTTDSY 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P+FFPGGNIGKLAI GT ND+AV  A+P+ ++ GFILEEG  +  L  +V SMAE A
Sbjct: 56  VVQPIFFPGGNIGKLAITGTVNDLAVCCAVPKMITAGFILEEGFALSDLNKIVHSMAEEA 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +AA + IV GDTKVV++G+ D +FINT G+GAI   +   A  +  GD ++VSGT+GDHG
Sbjct: 116 KAANVKIVAGDTKVVEKGSADGIFINTTGIGAISEQVCSPA--IKKGDCVVVSGTIGDHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACG 239
             IL+ R QLGL  ++ SDCA L  LIQ+L + + G++ +RD TRGG+   + E      
Sbjct: 174 IAILSARNQLGLLTDVQSDCASLHSLIQSLLEQVDGIRLMRDPTRGGLATSLVELCEDFQ 233

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             +EL E  +P++  V G C +LG D L  ANEGK+VI  +    ++V+  + +H  G++
Sbjct: 234 FSVELEEDLIPIRREVTGACNILGFDPLYLANEGKVVIVCDSTNKDKVIEIMQNHKYGEE 293

Query: 300 AALIGEVV----ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A +IG+V+        +      G  R +   +   LPRIC
Sbjct: 294 AKVIGKVISVNDSNGKLYSRTQIGTTRRIHRLNGMILPRIC 334


>UniRef50_A6LXR5 Hydrogenase expression/formation protein HypE n=3 Tax=Clostridium
           RepID=A6LXR5_CLOB8
          Length = 333

 Score =  353 bits (907), Expect = 5e-96,   Method: Composition-based stats.
 Identities = 148/340 (43%), Positives = 212/340 (62%), Gaps = 11/340 (3%)

Query: 1   MNN-IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDS 59
           MN  I+L HG GG+  + LI  LF + F N  L +++D A        A   ++AF+TDS
Sbjct: 1   MNKMIKLIHGDGGKHTKILIEQLFYKYFNNNILLQEQDSA-----TFTAVQGKMAFTTDS 55

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           +V+ PLFF GGNIGKLA+CGT ND+AVSGA P YLS  FI+EEG  M++L+ +V SM +T
Sbjct: 56  FVVKPLFFSGGNIGKLAVCGTINDLAVSGAKPFYLSSSFIIEEGFSMQSLEEIVKSMGQT 115

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
               G  IVTGDTKVV++G+VD +FINT+G+G I          +  GD ++V+G +G+H
Sbjct: 116 CLECGAKIVTGDTKVVEKGSVDGIFINTSGIGYIINGYEVKP--IEEGDKIIVTGEIGEH 173

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAAC 238
           G TI   R  L + G+  SDCA L   I+ L++  P +K +RD TRGG++ V+HEF++ C
Sbjct: 174 GTTIAVERYNLKVKGDYKSDCAPLFHFIEELKEQFPSIKIMRDPTRGGLSTVLHEFSSLC 233

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI L E  +P+  +V+ +  LLGLD L  A EG++V+ V+   A++VL  + S   GK
Sbjct: 234 KLGIHLIEKEIPISESVKAINNLLGLDPLYMACEGRMVLVVKETEAKKVLDIIRSIDQGK 293

Query: 299 DAALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            A +IGE ++   + + +   +G KR +       LPRIC
Sbjct: 294 GARIIGEFIKDSNQNIFIENGFGGKRVVSPLEVSMLPRIC 333


>UniRef50_P31905 Hydrogenase expression/formation protein hypE n=17 Tax=Bacteria
           RepID=HYPE_RALEH
          Length = 351

 Score =  351 bits (902), Expect = 2e-95,   Method: Composition-based stats.
 Identities = 159/323 (49%), Positives = 207/323 (64%), Gaps = 7/323 (2%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLA 76
           QLI  LF+ AF N WL +  DQA    A  +  G R+  +TD++V+ PLFFPGG+IG L+
Sbjct: 33  QLIQELFVAAFDNEWLRQGNDQA----AFAMPAGARMVMATDAHVVSPLFFPGGDIGSLS 88

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           + GT NDVA++GA P YL+  FILEEG P+  LK +V SMA  AR AG+ IVTGDTKVV+
Sbjct: 89  VHGTINDVAMAGAKPLYLAASFILEEGFPLADLKRIVESMAGAAREAGVPIVTGDTKVVE 148

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGEL 196
           +G  D +FI T G+G +PA I         GD +L+SGT+G+HG  IL+ RE L  D E+
Sbjct: 149 QGKGDGVFITTTGVGVVPAGILIDGAGARPGDAILLSGTMGEHGVAILSKRESLEFDTEI 208

Query: 197 VSDCAVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAV 255
            SD A L  L+ Q L  +PGV+ LRD TRGG+   ++E ++  G G+ L EAA+PV P V
Sbjct: 209 RSDSAALHDLVAQMLAVVPGVRVLRDPTRGGLATTLNEISSQSGVGMVLDEAAIPVLPQV 268

Query: 256 RGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG--VR 313
              CELLGLD L  ANEGKLV       A+ +LAA+  HPLG++A  IGEV+E     V+
Sbjct: 269 DAACELLGLDPLYVANEGKLVAICAAADADALLAAMRGHPLGREARRIGEVIEDGRHFVQ 328

Query: 314 LAGLYGVKRTLDLPHAEPLPRIC 336
           +   +G  R +D    E LPRIC
Sbjct: 329 MRTKFGGMRVVDWLSGEQLPRIC 351


>UniRef50_Q39ZF9 Hydrogenase expression/formation protein HypE n=3
           Tax=Deltaproteobacteria RepID=Q39ZF9_GEOMG
          Length = 349

 Score =  351 bits (901), Expect = 2e-95,   Method: Composition-based stats.
 Identities = 156/338 (46%), Positives = 206/338 (60%), Gaps = 8/338 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I L HGSGG+   QL++ L +   +   LA Q D A ++       G RLAF+TDSYV
Sbjct: 17  DLILLGHGSGGKLSHQLLDDLIIPTLSGIPLAGQNDAAVVEHG-----GQRLAFTTDSYV 71

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           +DP+FFPGGNIG LA+ GT ND+A+ GA P ++S G I+EEG     L  ++ SM   A 
Sbjct: 72  VDPIFFPGGNIGSLAVNGTVNDLAMMGARPLFISAGLIVEEGFSRTELAGILASMRGAAD 131

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           AAG+ IVTGDTKVV RG  D++FINT+G+GA+  +         AGDV++++GT+GDHG 
Sbjct: 132 AAGVRIVTGDTKVVPRGKADRIFINTSGIGAVEHDFAINGANARAGDVVIINGTIGDHGI 191

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACG 239
            ++  RE L L   + SDCA L  L+  +    G  V  LRD TRGGV   + E A    
Sbjct: 192 AVMAEREGLDLRTAIRSDCAALNDLVAEIIAAGGDAVHVLRDPTRGGVATTLKEIALQSD 251

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I L E  LP+  AV+GVC +LGLD L  ANEGKL+  V   AAE+VL  +  H LG+D
Sbjct: 252 KTITLREETLPLNGAVKGVCSILGLDPLYVANEGKLLAVVAPEAAERVLTRIKGHRLGRD 311

Query: 300 AALIGEVVERKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IG V E  G V++    G  R +++   E LPRIC
Sbjct: 312 AAIIGHVAEGGGRVQMETAVGGMRAVEMLAGEQLPRIC 349


>UniRef50_Q58089 Putative hydrogenase expression/formation protein MJ0676 n=40
           Tax=cellular organisms RepID=Y676_METJA
          Length = 335

 Score =  348 bits (892), Expect = 3e-94,   Method: Composition-based stats.
 Identities = 130/337 (38%), Positives = 200/337 (59%), Gaps = 6/337 (1%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYV 61
            I   HG+GG+ MQ+LI  + ++      +        LD +  +  GD+ + F+ D + 
Sbjct: 2   KITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGHT 61

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P+FFPGG+IG+LA+ GT ND+AV GA P  LS   I+ EG  +E L+ +V S+ ET++
Sbjct: 62  VKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETSK 121

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            A +AI+TGDTKV     VD + I+TAG+G +          +  GD ++VSG +G+HG 
Sbjct: 122 EAEVAIITGDTKVSD--GVDDIIISTAGIGIVDRGKAIRDCNVQEGDAIIVSGNIGEHGL 179

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQ-TLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
            IL  RE    +  + SD A +  LI+  L +   + A++D TRGG+   ++E A     
Sbjct: 180 AILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNI 239

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           GI + E  +P+   V+ +C++LGLD L  ANEGK+V+AV++  AE+ L  L  HPLGK+A
Sbjct: 240 GITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNA 299

Query: 301 ALIGEVV-ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            +IG    E KGV +  + G +R +D+P  +P+PR+C
Sbjct: 300 EIIGYATKEHKGVIIETIVG-RRIVDMPIGDPIPRVC 335


>UniRef50_B2UW48 Hydrogenase expression/formation protein n=12 Tax=Helicobacter
           RepID=B2UW48_HELPS
          Length = 332

 Score =  346 bits (888), Expect = 7e-94,   Method: Composition-based stats.
 Identities = 137/339 (40%), Positives = 204/339 (60%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+++ LA G+GG+    LI  +FM     P+L E       D  +  A G+    STDS+
Sbjct: 1   MDSVTLACGNGGKETNALIERVFM-----PYLKEFIVAFDEDAPKFKASGEY-CVSTDSF 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           VI PL F GG+IGKL +CG+ANDV+V G  P YL+ GFILEEGL +  LK ++ S+ +  
Sbjct: 55  VITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKEL 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             A + +++ DTKVV +G+VDKLFINT  +G         ++ L  G  +++S T+ +HG
Sbjct: 115 LKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKP-GISSRYLKQGQAIIISDTIANHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACG 239
           A++  +R ++ L   L SDC +L PL++ L      + ALRDATRGG+ +V++E+A +  
Sbjct: 174 ASLFAMRHEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSK 233

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I + E  +P+K   +G+CE+LGL+    ANEG  V+A+ +  A + L  L S+   K+
Sbjct: 234 VKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKN 293

Query: 300 AALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A +IGEV E     V L   +G +R L++P  E LPRIC
Sbjct: 294 ACVIGEVFENPYPSVVLKNAWGFERILEMPEGELLPRIC 332


>UniRef50_B7JF80 Hydrogenase expression/formation protein HypE n=32 Tax=Bacteria
           RepID=B7JF80_BACC0
          Length = 342

 Score =  346 bits (887), Expect = 9e-94,   Method: Composition-based stats.
 Identities = 135/341 (39%), Positives = 209/341 (61%), Gaps = 10/341 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           + NI L HG+GG   Q LI+S+         L + ED A L+++       RLA +TDS+
Sbjct: 7   LENIILDHGTGGLLSQDLISSIITAKLEGVHLGKMEDSAILEVSS-----RRLAMTTDSF 61

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           VIDP+FF  GNIGK+A+CGT ND+AVSGA P YLS   +LEEG P++ L+ ++ S+ ETA
Sbjct: 62  VIDPIFFGEGNIGKVAVCGTVNDLAVSGAKPLYLSLALVLEEGFPIKDLEEILDSIRETA 121

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHW-GAQTLTAGDVLLVSGTLGDH 179
           + AG+ IV GDTKVV++G VDK+FINT G+G    ++      ++  GD ++++G LG+H
Sbjct: 122 KEAGVYIVAGDTKVVKKGEVDKIFINTTGIGVFEGDVSPFSVNSIQEGDDIIITGQLGNH 181

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAA 237
              IL++RE LG +  + SDCA L  +I  L++  G  +  +RD TRGG+  V++E +  
Sbjct: 182 SIHILSIREGLGFEQRINSDCAPLNHMITELKNHFGDSIHCMRDITRGGLGTVLNEVSET 241

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
              GI++ E  +P+        ++LG++ +  ANEG + + V    +E+V+  L +   G
Sbjct: 242 INTGIKIQEKDIPMLAETIMAADMLGVNPMYLANEGNVCMFVSPEVSEEVVRVLKNTKYG 301

Query: 298 KDAALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           K+AA+IG+V + K   V +    G  + ++L +   LPR+C
Sbjct: 302 KEAAVIGKVTQTKERQVLMEAKSGELKLIELLYGAELPRLC 342


>UniRef50_A7I1Q2 Hydrogenase expression/formation protein HypE n=24
           Tax=Epsilonproteobacteria RepID=A7I1Q2_CAMHC
          Length = 390

 Score =  346 bits (887), Expect = 9e-94,   Method: Composition-based stats.
 Identities = 148/391 (37%), Positives = 209/391 (53%), Gaps = 59/391 (15%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEG----------- 50
             I L+HG GG+ M  LIN    +AF N  L    D A L+    + +            
Sbjct: 3   KQILLSHGGGGEEMNSLINDTIFKAFDNEILRRANDSAILNFPLDLDKNFDIISANFGDK 62

Query: 51  ------------------------------------------DRLAFSTDSYVIDPLFFP 68
                                                       LAF+TDS+V+ PLFF 
Sbjct: 63  TDYFNEKSQNFDVSNLNGQNKTDNMNFNVQNCHNKKNTQILCGNLAFTTDSFVVTPLFFN 122

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
           GG+IGK+A+CGT ND+A+ GA P +LSC FI+EEGL ++T + ++ SMA+TA+ AG+ IV
Sbjct: 123 GGDIGKIAVCGTVNDLAMVGAKPLFLSCAFIIEEGLEIDTFERILNSMAKTAKEAGVKIV 182

Query: 129 TGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
            GDTKVV RG+ D++FINT+G+G I          +  G  +L+SG +G HGA I+  R+
Sbjct: 183 CGDTKVVPRGSGDQIFINTSGIGQILK-AGVQMDCVKKGAKVLISGDIGRHGAVIMAARD 241

Query: 189 QLGLDGELVSDCAVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           ++ +  +L SDC  L   + + L++   + ALRDATRGG++AV++EFA    C I + E 
Sbjct: 242 EISVSTDLKSDCKPLNAAVTELLKNDVKILALRDATRGGLSAVLNEFAQHLNCEISIREN 301

Query: 248 ALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
            + V P V G+CELLG +  + ANEG  V  +E     + L  L      ++AA+IGEV 
Sbjct: 302 DIKVAPEVLGICELLGFEPYDLANEGTFVAFIEDGDEIKALEILRK--FNENAAIIGEVT 359

Query: 308 --ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
             E+  V L   YG +R L+ P  E LPRIC
Sbjct: 360 QNEKGRVILQNAYGTERFLEFPKGELLPRIC 390


>UniRef50_B9KGD0 Hydrogenase expression/formation protein HypE n=1 Tax=Campylobacter
           lari RM2100 RepID=B9KGD0_CAMLR
          Length = 336

 Score =  344 bits (882), Expect = 4e-93,   Method: Composition-based stats.
 Identities = 138/339 (40%), Positives = 190/339 (56%), Gaps = 19/339 (5%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I LAHG GG+ M  LIN +F   F N  L E  D A LD          LAFSTDS+
Sbjct: 14  MKQITLAHGGGGEEMNALINEIF-SIFENDVLKEANDAAILDD---------LAFSTDSF 63

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V++P+F    NIGKLA+CG+ NDV + GA P YLS   ILEEG  +E LK ++ S+ E  
Sbjct: 64  VLNPIFLKDINIGKLAVCGSVNDVLMVGAKPLYLSLALILEEGFEIEKLKIILNSIKEEC 123

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             AG+ +V GDTKVV +   D+++INT+ +G          + L +G  +LVS  +G HG
Sbjct: 124 DKAGVKLVCGDTKVVPKNKGDEIYINTSCIGK--NIQKINTKNLKSGCSILVSRDIGAHG 181

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACG 239
             +L  R  L  +  + SDC  L   +  L +    +KA+RDATRGG++AV++E++    
Sbjct: 182 CAVLVERNNL--EANIQSDCKSLKNEVLALLNAGISIKAMRDATRGGLSAVLNEWSKLSN 239

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             + + E  +PV   V GVCEL G +    ANEG  +I V++   ++ L  L       +
Sbjct: 240 LELLIYEEKIPVCDEVLGVCELFGYEPYELANEGTFIICVDKKDEQKALKILKQ--FNAN 297

Query: 300 AALIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGE+   E+  V L   YG KR L+ P  E LPRIC
Sbjct: 298 AAIIGEITPNEKARVVLENAYGAKRILETPKGELLPRIC 336


>UniRef50_B4U670 Hydrogenase expression/formation protein HypE n=2 Tax=Bacteria
           RepID=B4U670_HYDS0
          Length = 328

 Score =  343 bits (881), Expect = 4e-93,   Method: Composition-based stats.
 Identities = 125/336 (37%), Positives = 205/336 (61%), Gaps = 13/336 (3%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           ++L+HG G +  ++LI  +F++   N  L+ ++       A ++    +LA STDS+ ++
Sbjct: 3   VKLSHGGGAKETRELIEKIFLKHLKNDLLSNED-------ATILHLDGKLAISTDSFTVN 55

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+FF GG+IGKL++ G  ND++V GA P Y+S GFI+EEGL  E L+ +V S+ E A+  
Sbjct: 56  PIFFKGGDIGKLSVAGVVNDLSVMGAKPLYMSMGFIIEEGLAFEELERIVISIKEEAQKT 115

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           GI ++T DTKVV +G  DK++IN  G+G +       A  L  GD ++VSG +G+HGA I
Sbjct: 116 GIKLITADTKVVPKGLCDKIYINATGIGKLIKE-GISASNLQEGDAIVVSGPIGNHGAVI 174

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           +  R   G D ++ SDCA L   I+  L++   + A+RD TRGG+ + ++E + +    I
Sbjct: 175 MAHRN--GFDIDINSDCASLWEAIEPLLKENIEIHAMRDLTRGGLASALNELSQSSKVEI 232

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            + E  +P++ +V+G CE+LG++  + A EG  V+++ +   ++ L  L S  L + A +
Sbjct: 233 LIKEEDIPIEDSVKGFCEILGIEPFSLACEGTFVMSIPKKDVQKALDILKSQKLTQKAKV 292

Query: 303 IGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           IGE+++  ++G  +  LYG  R L+    E LPRIC
Sbjct: 293 IGEIIKKGKQGAYIQTLYGSVRYLEEAPGELLPRIC 328


>UniRef50_C3XF65 Hydrogenase expression/formation protein n=3 Tax=Helicobacter
           RepID=C3XF65_9HELI
          Length = 361

 Score =  343 bits (880), Expect = 6e-93,   Method: Composition-based stats.
 Identities = 136/367 (37%), Positives = 206/367 (56%), Gaps = 37/367 (10%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGD-RLAFSTDS 59
           M+ + LAHGSGG    + +  +FM  F      +    A  D     +  D +   STDS
Sbjct: 1   MDIVTLAHGSGGINAAEFVQKVFMPYF-----KDLMPYANEDCGIFSSIKDMKYVTSTDS 55

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           Y I+P+FF GGNIGKL +CG++NDVA+ G  P YL+ GFI+EEG  ++ LK +  S+A  
Sbjct: 56  YTINPIFFAGGNIGKLCVCGSSNDVAMMGGKPLYLNIGFIIEEGFNIDLLKQIAESIALE 115

Query: 120 ARAAGIAIVTGDTKVVQR-----GAVDK-LFINTAGMGAIPANIHWGAQTLTAGDVLLVS 173
            ++  I I++ DTKV+ +      A DK +FINT  +G++  +    A+ L+  D +++S
Sbjct: 116 CKSLNIKILSADTKVLPKVTDSTEAKDKLIFINTTCIGSVEKDC-ISAKNLSENDSIILS 174

Query: 174 GTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDI-PGVKALRDATRGGVNAVVH 232
           G +G HGA I   +  + +   + SDCA L P++++L      + A+RDATRGG+++V++
Sbjct: 175 GKIGSHGARIFLEQNNIAITSNIQSDCASLYPMLESLLQSNIPIHAMRDATRGGLSSVLN 234

Query: 233 EFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALH 292
           E+A +    I++ E  + +   V GVCE+LGL+  + ANEG  VIA+ +  AE+VL+ L 
Sbjct: 235 EWAISSHACIDIYEEKIQIDSEVHGVCEMLGLEPYDLANEGVCVIAMPKQYAEEVLSLLR 294

Query: 293 SHPLGKDAALIGEVVE-----------------------RKGVRLAGLYGVKRTLDLPHA 329
            H LG +A +IGEV +                        + V L   YG KR L+ P  
Sbjct: 295 GHTLGVNATIIGEVSKVFNPIFNLQDSKDNKAQISKTTYHQKVVLHTKYGSKRFLEYPQG 354

Query: 330 EPLPRIC 336
           E LPRIC
Sbjct: 355 ELLPRIC 361


>UniRef50_A4YFA3 Hydrogenase expression/formation protein HypE n=1
           Tax=Metallosphaera sedula DSM 5348 RepID=A4YFA3_METS5
          Length = 352

 Score =  342 bits (877), Expect = 1e-92,   Method: Composition-based stats.
 Identities = 140/354 (39%), Positives = 207/354 (58%), Gaps = 28/354 (7%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEA---FANPWLAEQEDQARLDLAQLVAEGDRLAFSTD 58
           N I L HG+GG  M  LI  +F++    F    L   +D A +         + + F+TD
Sbjct: 8   NVITLLHGAGGTYMHSLIRDVFLKLNDGFGEVGLEMMDDAAVV---------NGIVFTTD 58

Query: 59  SYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
           S+VI P+FF GG+IG+L++ GT ND+A+ G  P+ LS G +LEEG P + L+ +V S+ +
Sbjct: 59  SFVIRPIFFRGGDIGRLSVSGTVNDIAMMGGDPQALSLGVVLEEGFPKDMLEKIVESIKK 118

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH---------------WGAQT 163
           TA  A + +VTGDTKV++RG +DK+ INTAG+G  P  +                     
Sbjct: 119 TAEEANVHVVTGDTKVMERGNLDKIVINTAGIGTRPRQLDHNIETLRKSRQPSRWLVPTN 178

Query: 164 LTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDAT 223
           L  GD ++V+GTLGDH   +L+ RE +G +  ++SD A L  +I  L ++ G+   +D T
Sbjct: 179 LRDGDKIVVTGTLGDHAIAVLSSREGVGFESNVMSDVAPLNKMIMNLLEVGGIADAKDPT 238

Query: 224 RGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNA 283
           RGG+  ++ +++   G GI + E+ +PVK  VR   E LG+D L   NEGK V+AV    
Sbjct: 239 RGGLADLLQDWSEKSGLGIFIRESDIPVKDEVRAAVEFLGMDVLELGNEGKAVLAVSPEY 298

Query: 284 AEQVLAALHSHPLGKDAALIGEVVER-KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            + V+ ALHS PLGKDA +IGEV +  +GV +  + G  R +  P  +P+PRIC
Sbjct: 299 VKDVMDALHSDPLGKDATIIGEVRKDLEGVIMETVVGGNRYVGRPLGDPVPRIC 352


>UniRef50_C1SLC8 Hydrogenase expression/formation protein HypE n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SLC8_9BACT
          Length = 327

 Score =  341 bits (875), Expect = 2e-92,   Method: Composition-based stats.
 Identities = 141/336 (41%), Positives = 199/336 (59%), Gaps = 9/336 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I +A GSGG + +  ++ +      N  L +  D A      +V+   R AF+TDSY
Sbjct: 1   MEKITMAVGSGGTSSRSFVSEIIFSRLGNEHLLKASDAA------IVSTSGRTAFTTDSY 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FFPGGNIGK+A+CGT ND+ VSGA P YLS G I+ EG P+  L+ V+ SMAE  
Sbjct: 55  VVRPEFFPGGNIGKIAVCGTINDLLVSGAKPLYLSFGLIMPEGYPVADLERVIDSMAEEC 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           R A + IV GDTKVV +G  D L INT+G+G    + +     +  GD ++++  +  HG
Sbjct: 115 RKADVKIVCGDTKVVDKGGCDGLIINTSGIGESLRD-YTEPYNIQEGDAVILTSDVARHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
            +++  R +LG DGE++SDCA L  +   + ++  VK  RDATRGGV AV++E A+  G 
Sbjct: 174 MSVMLARGELGFDGEVLSDCACLKDVFSAVENL-NVKFARDATRGGVAAVLNEIASDSGK 232

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G  + E  +P+   V  +C++LG D L  ANEG  VI V    AE+ L+ + +   G+ A
Sbjct: 233 GFLMRETDIPMDENVGYLCDMLGFDPLAVANEGLAVIIVSEEDAEKALSNICACENGQRA 292

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A+ G V E K V L    G KR +++P  E LPRIC
Sbjct: 293 AIAGRV-EGKNVILETSIGGKRHIEMPAGELLPRIC 327


>UniRef50_B5YJH9 Hydrogenase expression/formation protein HypE n=1
           Tax=Thermodesulfovibrio yellowstonii DSM 11347
           RepID=B5YJH9_THEYD
          Length = 332

 Score =  337 bits (864), Expect = 4e-91,   Method: Composition-based stats.
 Identities = 143/339 (42%), Positives = 204/339 (60%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ I L HGSGG+ M +LI       F  P L    D A + L        ++A +TDSY
Sbjct: 1   MDKILLGHGSGGKLMYELIKKYIAPIFELPSL---MDSAIVSLNH----SGKIAITTDSY 53

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IG LAI GT ND+AV GA+P YL+ GFILEEG P+   + +++S++ +A
Sbjct: 54  TVSPIFFPGGDIGDLAINGTVNDLAVVGAVPLYLTVGFILEEGFPLSDFEKILSSISSSA 113

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           + AG+ IV GDTKVV +G  D +FINT+G+G IP  +      +  GD +L+SG++G+HG
Sbjct: 114 KKAGVKIVAGDTKVVDKGKGDGIFINTSGIGVIPEGVELSPLKIEMGDKILISGSIGNHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTL--RDIPGVKALRDATRGGVNAVVHEFAAAC 238
             +++ R     +  ++SD   L  LI  +     P VK +RD TRGG+   + E A   
Sbjct: 174 IAVMSERNGFTFEPPVLSDTRALNGLIDQIMKEFTPFVKVMRDPTRGGLATTLKELALES 233

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
              I + E+A+P+   V+G CELLGLD L  ANEG  V  V+ + AE++L  + SHP G+
Sbjct: 234 LKDILIYESAIPLHDTVKGACELLGLDPLYVANEGIFVAIVKADVAEKILQLMKSHPFGE 293

Query: 299 DAALIGEVVERKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
           ++A+IGEV  + G V L    G  R +D+   E LPRIC
Sbjct: 294 ESAIIGEVTGKGGKVLLKTFIGGTRIVDMLPGEQLPRIC 332


>UniRef50_A6C222 Hydrogenase expression/formation protein HypE n=1 Tax=Planctomyces
           maris DSM 8797 RepID=A6C222_9PLAN
          Length = 358

 Score =  337 bits (864), Expect = 4e-91,   Method: Composition-based stats.
 Identities = 156/339 (46%), Positives = 205/339 (60%), Gaps = 9/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + + LAHG GG+  ++LI         N +L   +D ARL           LAF+TDS+V
Sbjct: 25  DCVTLAHGEGGRLSRKLIQERIASVLKNEFLETSDDAARLP-----RVDGPLAFTTDSFV 79

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG+IG LAI GT ND+AVSGA P +L+   ILEEG P+  L  V+ S+AE A 
Sbjct: 80  VSPLFFPGGDIGSLAIYGTVNDLAVSGAHPLWLTLSLILEEGFPLMLLDRVLQSLAEAAS 139

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           +  + IV GDTKVV RGAVD LFINTAG+G +   +  G   L  GD L+VSG +G HG 
Sbjct: 140 STAVKIVAGDTKVVPRGAVDGLFINTAGVGKLTEPVPPGPAFLREGDELVVSGPIGQHGI 199

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACG 239
            +L  REQL LD    SDC  L   ++ LR+  G  +  LRDATRGGV AV+ E+A + G
Sbjct: 200 AVLAAREQLQLDPLPHSDCGSLLTAVEQLREALGDRICCLRDATRGGVAAVLQEWAGSSG 259

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             + + E  +PV P V+G+ ELLGLD L+ ANEG ++IAV + A ++ ++ L S     D
Sbjct: 260 LTLSIDERCVPVTPGVKGMSELLGLDPLHIANEGTMLIAVRQGAGQEAVSVLQSLSKTAD 319

Query: 300 AALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A LIG V  R    V +    G+++ L  P   PLPRIC
Sbjct: 320 ARLIGSVKGRGVAAVTVKRTLGLEQPLHDPLGSPLPRIC 358


>UniRef50_B4S328 Hydrogenase expression/formation protein HypE n=2
           Tax=Proteobacteria RepID=B4S328_ALTMD
          Length = 350

 Score =  335 bits (859), Expect = 1e-90,   Method: Composition-based stats.
 Identities = 143/339 (42%), Positives = 202/339 (59%), Gaps = 10/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
            +IQLA G+GG   ++LI+ +F         A ++     D A +  +G  L+ +TDS+V
Sbjct: 18  ESIQLAQGNGGTLTKRLIDHVFKNK------ANKDLDLLHDAATVTFDGPYLSITTDSFV 71

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P  FPGGN+G L++ GT ND+AV GA PRY+S  FI+EEG  + TLK +V  M + A 
Sbjct: 72  VSPPTFPGGNVGALSVYGTVNDLAVVGATPRYISTAFIIEEGFSLSTLKQIVNGMHQAAE 131

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
              +AIVTGDTKVV +G+   +FINT G+G       W    + AGD +LVSG++GDHGA
Sbjct: 132 ETKVAIVTGDTKVVPKGSGGGVFINTTGVGDSRDAPIWDTSLIKAGDHVLVSGSVGDHGA 191

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            +L  RE  GL G+L SDC  + PLI  ++ + GV+ +RD TRGG++ ++H+ A   G  
Sbjct: 192 CVLLAREDYGLQGQLKSDCGSVVPLIDPIKHLEGVRFVRDPTRGGLSVLLHDVANETGFD 251

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IEL E  +PV+P V  VCE+LG D    A EG++V  V  + + +VL    S   G+ A 
Sbjct: 252 IELIENNIPVRPEVASVCEILGFDPFVLACEGRIVAVVAPDISGKVLEHWRSIRNGEQAE 311

Query: 302 LIGEV---VERKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
            IG +    E KG V +    G +R ++    EPLPRIC
Sbjct: 312 HIGVIVKNTESKGRVTIVTPMGGRRFMNELEDEPLPRIC 350


>UniRef50_C8PGA7 Hydrogenase expression/formation protein HypE n=1 Tax=Campylobacter
           gracilis RM3268 RepID=C8PGA7_9PROT
          Length = 395

 Score =  333 bits (855), Expect = 5e-90,   Method: Composition-based stats.
 Identities = 155/397 (39%), Positives = 211/397 (53%), Gaps = 66/397 (16%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDL---------------AQL 46
             I L+HG GG+ M +LIN +   AF N  L    D A L+L                  
Sbjct: 3   ETILLSHGGGGEEMNRLINEMIFAAFDNEILRANNDSAILNLDAGAGFDRTAPSSALNSA 62

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPM 106
            + G  LAFSTDS+V+ PLFF GG+IGK+A+CGT ND+A+ GA P +LSC  I+EEGL +
Sbjct: 63  ASFGGELAFSTDSFVVTPLFFNGGDIGKIAVCGTVNDLAMVGAKPLFLSCALIIEEGLSL 122

Query: 107 ETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTA 166
             L+ ++ SMA TAR+ G+ +V GDTKVV RG  DK+FINT+G+G +        Q + A
Sbjct: 123 SELRRILDSMASTARSCGVRVVCGDTKVVPRGKCDKIFINTSGIGRVLRPARV--QNIKA 180

Query: 167 GDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRG 225
           G  +L+SG +G HGA IL +R+++ L  EL SDC  L   ++ L      ++A+RDATRG
Sbjct: 181 GAKILLSGDIGRHGAVILAVRDEIALSSELQSDCKPLCAAVEELILQGVKIQAMRDATRG 240

Query: 226 GVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNA-A 284
           G++AV++EFA++ G    + E  + +   V GVCELLG +    ANEG  V  VE +A A
Sbjct: 241 GLSAVLNEFASSSGLEFLVREEDIKISDEVVGVCELLGFEPYELANEGTFVAIVEDDAEA 300

Query: 285 EQVLAALHSHPLGKDAALIGEVVE------------------------------------ 308
            + L  L       +AA+IGEV E                                    
Sbjct: 301 NRALEILRE--FDANAAIIGEVREVGHDKGEFKGSLAPKLGTWDESTGASDAGTVSENRA 358

Query: 309 ---------RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
                    +  V L   YG +R L+LP  E LPRIC
Sbjct: 359 GQFQTPHATKGRVILQNAYGSQRFLELPKGELLPRIC 395


>UniRef50_C9LR03 Hydrogenase expression/formation protein HypE n=1 Tax=Dialister
           invisus DSM 15470 RepID=C9LR03_9FIRM
          Length = 327

 Score =  332 bits (851), Expect = 1e-89,   Method: Composition-based stats.
 Identities = 140/335 (41%), Positives = 196/335 (58%), Gaps = 10/335 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            I L HGSGG+   +LI  +F   F +  L + ED A L              ++DS+V+
Sbjct: 2   KITLKHGSGGEESGRLIKDIFASVFDDEILLKMEDSAVLP-----PLHGNPVLTSDSFVV 56

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           +PLFF GG+IGKL++CGT ND++  GA P YL+  FILE GL  + L  +V SM ETA  
Sbjct: 57  EPLFFKGGDIGKLSVCGTVNDLSSMGARPLYLTASFILETGLDTDILGKIVQSMKETAEE 116

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ IV GDTKV++      L+INTAG+G  P++     + + +GD L+++GTLGDH A 
Sbjct: 117 AGVRIVAGDTKVIEGKG--GLYINTAGVGERPSSRDISCRNMKSGDTLILTGTLGDHHAA 174

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACGCG 241
           +L  R  LG++ E+ SDCA L  +++ L +    V  +RD TRGG+  V +E A +    
Sbjct: 175 VLTNR--LGIESEIESDCAPLNHMVEELLEGNISVHTVRDITRGGLATVANELAVSSSVR 232

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IEL E  +PV   V+G   +LGLD L   NEGK++IAV    AE+ +  L  +  G++A 
Sbjct: 233 IELEEELIPVSDIVQGFTGILGLDPLTMGNEGKMIIAVSPKDAEKAVGILRRNKYGRNAV 292

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
             G+V+E KGV L    G  R +     E LPRIC
Sbjct: 293 AAGQVLEGKGVYLRTALGGLRRVLPLRGEGLPRIC 327


>UniRef50_C9KK60 Hydrogenase expression/formation protein HypE n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KK60_9FIRM
          Length = 348

 Score =  328 bits (842), Expect = 2e-88,   Method: Composition-based stats.
 Identities = 152/340 (44%), Positives = 197/340 (57%), Gaps = 9/340 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG+GG+    LI  +F   F NP     +D A L +        R AF+TD +++
Sbjct: 12  RVTLAHGAGGRQTAALIARVFARHFQNPDFTA-DDAAILPVGNFAT--GRTAFTTDGFIV 68

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            P  FPGGNIGKL+ICGT ND+A  GA+PRYLSC F +EEG P+  L A+  +MAETA+A
Sbjct: 69  SPWQFPGGNIGKLSICGTVNDLACMGAVPRYLSCAFQIEEGFPLRDLDAIAAAMAETAKA 128

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ IV GDTKV  RG VD +FI T G+G +  +         AGD ++V+G +G HGA 
Sbjct: 129 AGVRIVAGDTKVAGRGQVDGVFITTTGLGELLPDAEPSGSRAEAGDAIIVTGDVGRHGAA 188

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTL----RDIPGVKALRDATRGGVNAVVHEFAAAC 238
           IL  R    +D  + SDCA L   ++ L     D   +  +RDATRGGV  V+HE AA  
Sbjct: 189 ILVARRDFAIDAAITSDCAPLAATVRALFAAVPDKSAIHTIRDATRGGVGTVLHEIAAES 248

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GIEL   A+PV P VRGVC LLGL+ L  A EG+LV+   +  A +++  L + P  +
Sbjct: 249 HVGIELDAPAIPVAPEVRGVCGLLGLEPLYLACEGRLVLFAPQAIAPKLVETLRALPDSR 308

Query: 299 DAALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            AA+IG V       V L    G K  L  P  E LPRIC
Sbjct: 309 QAAIIGHVTPDFSGRVVLRTEIGTKTLLPEPSGELLPRIC 348


>UniRef50_B2KBC5 Hydrogenase expression/formation protein HypE n=1
           Tax=Elusimicrobium minutum Pei191 RepID=B2KBC5_ELUMP
          Length = 335

 Score =  322 bits (826), Expect = 9e-87,   Method: Composition-based stats.
 Identities = 139/339 (41%), Positives = 198/339 (58%), Gaps = 10/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           N I LAHG+G +  +  I    ++ F +  LAE  D A++           + F+TDSYV
Sbjct: 3   NKITLAHGAGAEVSRGFIKKTLLKYFKSKSLAELSDSAKI-----KINSKDILFTTDSYV 57

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           ++P+FFPGGNIG LA+CGT ND++VSG   +Y+S G I+EEGL ++ L+ ++ ++A  A+
Sbjct: 58  VNPVFFPGGNIGDLAVCGTVNDISVSGGDIKYISLGLIIEEGLDLKELEQILKAVALRAK 117

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            AG+ IVTGDTKVV+RG  DK+FINT+G+G   A+    A+ +  GD ++VSG L +HG 
Sbjct: 118 EAGVEIVTGDTKVVERGGADKIFINTSGIGQAIADATVKARNIKKGDKIIVSGNLAEHGI 177

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHEFAAACG 239
           +++N R +LGL G L SD A L  + +   L+    +   RD TRGG+   + E A    
Sbjct: 178 SVMNERHKLGLKG-LKSDVAPLNKITKALFLKFDKDIHMTRDLTRGGLAGALKEIAEQAK 236

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             IEL E+ +P+  AV+G   +LG+D L  ANEGK V   +   AE VL  L +   GKD
Sbjct: 237 KDIELEESRVPLSKAVKGAVSILGVDPLQTANEGKFVCIADAKKAESVLKLLKTFAYGKD 296

Query: 300 AALIGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A + G V    +  V +    G  R L       LPRIC
Sbjct: 297 AKICGTVLKTRKGRVYIKTPLGASRALAEHEGSNLPRIC 335


>UniRef50_D1VJK8 Hydrogenase expression/formation protein HypE n=1 Tax=Frankia sp.
           EuI1c RepID=D1VJK8_9ACTO
          Length = 409

 Score =  317 bits (812), Expect = 5e-85,   Method: Composition-based stats.
 Identities = 166/384 (43%), Positives = 218/384 (56%), Gaps = 54/384 (14%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
            +I +AHG+GG+A   L++++F+EAF NP L   +D A +D       G RL  +TDSYV
Sbjct: 31  EHITMAHGAGGKATAALVDAVFLEAFRNPALEALDDGAHVDAG-----GARLVLTTDSYV 85

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG IG LA+ GT ND+AV GA P YL+CGF+LEEG  +  L+ VV +MAE AR
Sbjct: 86  VTPLFFPGGCIGDLAVNGTVNDLAVCGAKPLYLTCGFVLEEGFAVADLRRVVAAMAEAAR 145

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN------------------------- 156
            AG+ +VTGDTKVV RG  D  ++NT G+G                              
Sbjct: 146 TAGVTLVTGDTKVVPRGRADGCYVNTTGLGLFHPGGSTLDDESPMEGVVAADDPVGPWPV 205

Query: 157 ---------------IHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCA 201
                             G      GDV+LVSG +GDHG TI+  R +L L+ +L SD A
Sbjct: 206 GYTPPGHRPTEPDRLDRLGMAHARPGDVVLVSGPIGDHGITIMLARGELDLEADLRSDTA 265

Query: 202 VLTPLIQTLRDI-------PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
            L+ L++ L           GV+A+RDATRGGV  V++E A A G G+ + E A+PV+ A
Sbjct: 266 PLSGLVERLLTATSGPEHGGGVRAMRDATRGGVATVLNELAMAAGVGVVIDEDAVPVREA 325

Query: 255 VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG--V 312
           VRG  ELLG+D L  A EG+LV  V   AA+  LAAL + PLG  A +IG VV+     V
Sbjct: 326 VRGAAELLGIDPLYVACEGRLVAVVAPEAADAALAALLADPLGAGATVIGRVVDDPPGLV 385

Query: 313 RLAGLYGVKRTLDLPHAEPLPRIC 336
            L   +G  R +D+   +PLPRIC
Sbjct: 386 LLNTAFGGTRIVDMLVGDPLPRIC 409


>UniRef50_D2LQB8 Hydrogenase expression/formation protein HypE n=3
           Tax=Aciduliprofundum boonei T469 RepID=D2LQB8_9EURY
          Length = 339

 Score =  313 bits (802), Expect = 6e-84,   Method: Composition-based stats.
 Identities = 116/341 (34%), Positives = 196/341 (57%), Gaps = 9/341 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           ++ I++  G+GG+AM++LI  + ++        +       D A +  +G+ + F+ D +
Sbjct: 3   LDRIRMVDGAGGEAMERLIKEIILDNITLRSAGKVSLDDLDDGATISLDGEDIVFTIDGH 62

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IGKLA+ GT ND+AV GA P  L+   I+E+G  M++LK ++ S+ +T 
Sbjct: 63  TVKPIFFPGGDIGKLAVSGTVNDLAVMGAKPLALAISLIIEDGFSMDSLKNIMISIDKTG 122

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +   + I+TGDTKVV+    DK+ I     G   A+          GD +L++G +G+HG
Sbjct: 123 KDVPVPIITGDTKVVE----DKIGIFAISAGIGKADKIVRDSGARVGDFVLINGGIGEHG 178

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VKALRDATRGGVNAVVHEFAAA 237
             I++ RE +  +  LVSD + L  LI+ +    G   + A++D TRGG++  ++E A+ 
Sbjct: 179 FAIMSKREGIDFETSLVSDVSPLWSLIEDVAKCIGWENIHAMKDPTRGGLSEALNEMASK 238

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
              GIE+ E ++P+K +V+   E+LG+     ANEGK+V+ V     +  + A+  +  G
Sbjct: 239 ANVGIEIDEESVPIKSSVKAASEMLGISPFIMANEGKVVMIVADGYQDDAIEAMRKNKNG 298

Query: 298 KDAALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           KDAA+IG V+      V +    G KR ++ P  +P+PR+C
Sbjct: 299 KDAAIIGRVIREYPGKVIIKTKIGGKRFIERPIGDPVPRVC 339


>UniRef50_A4TCL4 Hydrogenase expression/formation protein HypE n=15 Tax=Bacteria
           RepID=A4TCL4_MYCGI
          Length = 373

 Score =  312 bits (801), Expect = 8e-84,   Method: Composition-based stats.
 Identities = 142/326 (43%), Positives = 193/326 (59%), Gaps = 8/326 (2%)

Query: 14  AMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIG 73
              +L+  LF+ AF +   A   D A +++      G RLAFSTDS+V+ P+ FPGG IG
Sbjct: 53  MSGELVEHLFLPAFGSAAEAGLADSAVVEIG-----GARLAFSTDSFVVKPMVFPGGTIG 107

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
            LA+ GT ND+A++GA+P  LS  FILEEG  ++ L  V  ++   A AAG+ +VTGDTK
Sbjct: 108 DLAVNGTVNDLAMAGAVPAVLSTAFILEEGTALDHLARVAQAVGTAALAAGVKLVTGDTK 167

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
           VV  G  D ++INT G+G +   +    Q    GDV++VSG LG HG  +L+ RE L   
Sbjct: 168 VVDSGHGDGVYINTTGIGLVDPRVDIRPQRAAPGDVVIVSGDLGVHGIAVLSCREGLEFA 227

Query: 194 GELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVK 252
             + SD A L  L+  + +    +  LRD TRGG+ A ++E A A G G+ +++ ALP+ 
Sbjct: 228 TSVASDAAPLHGLVAAMVETGADIHTLRDPTRGGLAATLNEIARAAGVGVSIADTALPIP 287

Query: 253 PAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG- 311
             VR  C +LGLD L  ANEGKLV  V    A++VLAA+H+HPLG  +A+IG  V     
Sbjct: 288 QEVRDACSMLGLDPLYVANEGKLVAFVPAADADEVLAAMHAHPLGAQSAVIGTCVPDHPG 347

Query: 312 -VRLAGLYGVKRTLDLPHAEPLPRIC 336
            V      G  R +DLP  E LPRIC
Sbjct: 348 MVVAKTALGGNRVVDLPIGEQLPRIC 373


>UniRef50_C7NVH7 Hydrogenase expression/formation protein HypE n=1 Tax=Halorhabdus
           utahensis DSM 12940 RepID=C7NVH7_HALUD
          Length = 365

 Score =  311 bits (798), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 135/342 (39%), Positives = 198/342 (57%), Gaps = 12/342 (3%)

Query: 2   NNIQLAHGSGGQAMQQLINSL----FMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFST 57
             I  AHG+GG  M +L++++    F +A A+  LA  +D +     Q + +   +  +T
Sbjct: 29  EVITHAHGAGGGQMTELVDAVAVSQFADAAADVGLAALDDGSV----QPIDDDHSVVVTT 84

Query: 58  DSYVIDPLFFPGGNIGKLAICGTANDVAVSGA-IPRYLSCGFILEEGLPMETLKAVVTSM 116
           DS+V+ PLFF GG+IG+LA+ GT ND+A+ GA  P  L+   I+E G P  T++ V  SM
Sbjct: 85  DSHVVTPLFFRGGDIGRLAVSGTVNDLAMMGATEPLALTSSLIIEAGTPQTTVERVTESM 144

Query: 117 AETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTL 176
            E    AG  + TGDTKV+  G +D L INT G+  +P   H     L+ GD L+VSGT+
Sbjct: 145 REACEEAGATVTTGDTKVMGSGEMDTLAINTTGVAVVPKGGHVPDAGLSVGDRLIVSGTV 204

Query: 177 GDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAA 236
           GDHG ++L+ RE     G+L SD   +  L++   D   V A++D TRGG+  V++E A+
Sbjct: 205 GDHGISLLSEREGFDFGGDLESDVQPVNDLVRAAMDAGEVTAMKDPTRGGLATVLNEMAS 264

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
               GI++ E ++PV   V    E+LG++  + A EG +V+ V    A  VL AL  +P 
Sbjct: 265 KADVGIDVEERSVPVSGPVSSAGEVLGIEPFDVACEGVVVMGVASEDAADVLDALRDNPK 324

Query: 297 GKDAALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           G+DAA++GEVV+     V L   +G +R L  P  E LPRIC
Sbjct: 325 GEDAAIVGEVVDDHTGQVVLDTGFG-RRYLSPPEGEQLPRIC 365


>UniRef50_A8A9S1 Hydrogenase expression/formation protein HypE n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8A9S1_IGNH4
          Length = 337

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 124/339 (36%), Positives = 189/339 (55%), Gaps = 8/339 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLD-LAQLVAEGDRLAFSTDSYV 61
           ++ LA G GG+  ++ I +  +  F    L         D  A  + +   L  S DSY 
Sbjct: 2   SVTLAVGGGGRETEEFIKNFILPLFKIRSLGSVGLDDLEDGAAVPIGDNKYLVVSVDSYT 61

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P FFPGG+IGKLA  G+ NDVAV GA P+ L    I+EEG  +  LK ++ SM+E   
Sbjct: 62  VSPPFFPGGDIGKLAATGSLNDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMSEVTN 121

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           +  +A++ GDTKV+ +G+VDK+ I+T G+G     +    +    GD +LV+G +GDHGA
Sbjct: 122 SLNVALLGGDTKVMPKGSVDKIVISTVGIGIAEGPLLTLDRG-EPGDKVLVTGPVGDHGA 180

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACG 239
           TIL L+  L +   L SD   + P ++ LR+  G  +KA +D TRGG+   ++E A    
Sbjct: 181 TILALQFGLQVKT-LKSDVRPVWPAVKALREALGEDLKAAKDPTRGGLAMALNELAERSK 239

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             + + EA +P++ AV+   E+LG++ L  A+EG+ V  V+ + AE+ L  L      ++
Sbjct: 240 TTVYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKAGF-EE 298

Query: 300 AALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGE+ + K   V      G  R L+ P  E +PRIC
Sbjct: 299 AAIIGELRKGKPGYVISRTPVGGLRLLEKPSGELVPRIC 337


>UniRef50_B5Y920 Hydrogenase expression/formation protein HypE n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y920_COPPD
          Length = 319

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 130/337 (38%), Positives = 193/337 (57%), Gaps = 19/337 (5%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ I L+ G+GG+ M Q +                 D A +         +  AF+ DS+
Sbjct: 1   MDKITLSIGTGGEEMTQFLQKTVFPILEESISG---DAALV---------NHTAFTIDSF 48

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V +P FFPGG+IG LA+ GT ND+  +GA P  L+   ILEEGL ME ++ ++    ETA
Sbjct: 49  VAEPPFFPGGSIGTLAVSGTVNDLVAAGAKPSALALSLILEEGLDMEVVRRILQDAKETA 108

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           + A I IVTGDTKVVQ+GA DK+F+ T+G+G    +    A     GD ++V+G +  HG
Sbjct: 109 KLAQIKIVTGDTKVVQKGAADKVFVTTSGIGQKVLDFESPA----PGDAVVVTGDIARHG 164

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACG 239
           AT+L   ++  L+ +L SDC  L  LI  L+   G +K +RD TRGGV  ++HEF +   
Sbjct: 165 ATMLLASKKFELESQLTSDCEPLCWLIDVLKPFEGFLKWMRDPTRGGVGTILHEFCSQFS 224

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            G+ L +  +P+ P V+G+CELLGL+ L+ A+EG++VI +  + A + L +L   P   +
Sbjct: 225 LGVRLFQKQIPIMPEVKGICELLGLEPLHLASEGRMVIVISPDKAHEFLESLK--PFAPN 282

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A++IGEVV+        + G +  +     E LPRIC
Sbjct: 283 ASVIGEVVDDHKTLTQVVDGYETYVPPLTGEILPRIC 319


>UniRef50_D1Y5N1 Hydrogenase expression/formation protein HypE n=1
           Tax=Pyramidobacter piscolens W5455 RepID=D1Y5N1_9BACT
          Length = 331

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 135/335 (40%), Positives = 177/335 (52%), Gaps = 10/335 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L  GSGG+    L+ S+              D  +            LA +TD + + 
Sbjct: 5   ISLGEGSGGRLTADLVASVIKNF-------AACDGQKGGCEDCTFIEGNLAVTTDGFTVS 57

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P FFPGG++G LA+CG  ND+AV G  P++L+ G I+EEGLP   L  +V S A    A 
Sbjct: 58  PRFFPGGDMGHLAVCGATNDLAVRGVRPQWLTLGMIIEEGLPRAELLRLVRSAARQCEAL 117

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G  +  GDTKVV RGA + +F N   +G        G   L  GD L++S   G HGA I
Sbjct: 118 GATLAAGDTKVVPRGACEGVFFNVTALGRAVTPRPLGMNRLQPGDALILSTPPGRHGAVI 177

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
             LR  L   G L SDCA L PL+  L  + G++ +RD TRGG+  V+ E+A A G G+E
Sbjct: 178 AALRYGLD-RGGLESDCAALWPLLGPLLPLDGLRCMRDCTRGGLGTVLCEWAEATGLGME 236

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + E  L + P+V  +C++LG D L  A+EG  +IA      E  LA L  HPLG+DAALI
Sbjct: 237 IEEERLALHPSVAAICDILGFDPLYLASEGCALIACAPAETEIALARLRRHPLGRDAALI 296

Query: 304 GEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           G V       V L    G  R +D+P  E LPRIC
Sbjct: 297 GAVTAEHAGLVGLKTRLGGSRIVDMPVGEILPRIC 331


>UniRef50_A7H7N3 Hydrogenase expression/formation protein HypE n=1
           Tax=Anaeromyxobacter sp. Fw109-5 RepID=A7H7N3_ANADF
          Length = 340

 Score =  310 bits (795), Expect = 5e-83,   Method: Composition-based stats.
 Identities = 157/339 (46%), Positives = 207/339 (61%), Gaps = 10/339 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYV 61
            I L HGSGG+AM+QLI  +F+   A+P   +    + LD    +  GDR L  +TDS+V
Sbjct: 7   KIGLKHGSGGRAMRQLIEDVFL-TLASPV--DGIGLSALDDGAAIRVGDRWLVVTTDSHV 63

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGA-IPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           + P+FFPGG+IG+L++ GT ND+A+ GA  P  L+C  +LE+G P   L+ VV SM ETA
Sbjct: 64  VHPIFFPGGDIGRLSVSGTVNDLAMMGATEPLGLTCAVVLEDGFPRADLERVVASMRETA 123

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           R A   IVTGDTKV+ +  VD + +NT   G   A        L AGD+L+V+GT+GDHG
Sbjct: 124 REANAPIVTGDTKVMGKDEVDGIVLNTT--GVALAERVVSDAGLRAGDLLIVTGTIGDHG 181

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAAC 238
             I++ R  L L+G+L SD A L  L++      G  V A++D TRGGV  V+HE AA  
Sbjct: 182 MAIMSRRHDLRLEGDLRSDVAPLNGLVREALRAGGEDVVAMKDPTRGGVAGVLHEMAAKG 241

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI + E ALPV+  VR   E++G+D L  ANEGK VIAV   AA++VLAAL +HPLG 
Sbjct: 242 KVGIVIDETALPVRDEVRAAGEMIGIDPLLVANEGKAVIAVRARAADKVLAALRAHPLGA 301

Query: 299 DAALIGE-VVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            A +I   + ER G  +      KR L  P  E LPRIC
Sbjct: 302 SATVIATAIAERPGAVILDTGFGKRMLAEPEGELLPRIC 340


>UniRef50_D1A5C3 Hydrogenase expression/formation protein HypE n=2
           Tax=Actinomycetales RepID=D1A5C3_THECD
          Length = 437

 Score =  309 bits (793), Expect = 7e-83,   Method: Composition-based stats.
 Identities = 148/313 (47%), Positives = 198/313 (63%), Gaps = 4/313 (1%)

Query: 28  ANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAV 86
            +P +   +  A   ++  +A  G RLAF+TDSYV+ PLFFPGG+IG LA+ GT ND+AV
Sbjct: 125 GSPTVFADDPAATARMSDAMATAGPRLAFTTDSYVVSPLFFPGGDIGDLAVNGTVNDLAV 184

Query: 87  SGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFIN 146
            GA P YLS GFILEEG  +  L+ ++ SMA  A+ AG+ IVTGDTKVV RG  D  +I 
Sbjct: 185 CGARPLYLSAGFILEEGFEVADLQRIIASMAAAAQRAGVQIVTGDTKVVGRGKADGCYIT 244

Query: 147 TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPL 206
           TAG+G +   I   A T+  GD +LVSG +G+HG TI+  R +L ++ +L SD A L  L
Sbjct: 245 TAGVGLLDRPITLDAATVRPGDAVLVSGPIGEHGVTIMLARGELDIEADLTSDTAPLNGL 304

Query: 207 IQTLRDI-PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD 265
            + L +   GV+ LRDATRGGV  V++E A A    I + EAA+P++P V G CELLG+D
Sbjct: 305 TEALLNATAGVRVLRDATRGGVATVLNEIAQASQTAIVVDEAAVPIRPVVAGACELLGID 364

Query: 266 ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG--VRLAGLYGVKRT 323
            L  A EG+ V  V+   A++ L  L +HPLG+DAA+IG V +     V     +G  R 
Sbjct: 365 PLYVACEGRFVAIVDGAHADKALTVLQTHPLGRDAAIIGHVHDDPPSLVLGRTAFGGTRV 424

Query: 324 LDLPHAEPLPRIC 336
           +D    +PLPRIC
Sbjct: 425 IDTLVGDPLPRIC 437



 Score = 54.1 bits (129), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 23/48 (47%), Positives = 29/48 (60%)

Query: 2  NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAE 49
            I LAHG+GG+A Q L+ SLF+ AF NP L   +D A LDL    + 
Sbjct: 24 ERITLAHGAGGKATQSLVESLFVAAFRNPALERLDDGAVLDLPAAASG 71


>UniRef50_C1TK23 Hydrogenase expression/formation protein HypE n=1
           Tax=Dethiosulfovibrio peptidovorans DSM 11002
           RepID=C1TK23_9BACT
          Length = 328

 Score =  306 bits (785), Expect = 6e-82,   Method: Composition-based stats.
 Identities = 132/338 (39%), Positives = 184/338 (54%), Gaps = 12/338 (3%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  + L  GSGG+   +LI   F   F        +   + DL          A + D +
Sbjct: 1   MGKLNLGQGSGGRLTSELIGK-FKAQFD-------DVNVQRDLEDCTMISPEWAVTIDGF 52

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+ FPGGNIGKLAICG  ND+AV G  P++++   I EEGL  E L     S A   
Sbjct: 53  TVSPMDFPGGNIGKLAICGGTNDLAVRGIEPKFVTLSVIAEEGLDEEELLRYGRSAASVC 112

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
               + +  GDTKVV +G VD LF+  A MG  P     G   +  GD L V+ ++G HG
Sbjct: 113 HGLEVKLAAGDTKVVPKGTVDGLFLTVASMGQ-PLGKPLGMDHIKPGDRLAVTTSIGRHG 171

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
           ATI ++R  L ++G L SDCA L PL++ L  +PGV+A+RD TRGG+   + E+A   G 
Sbjct: 172 ATIGSIRFDLNVEG-LSSDCAPLWPLVKPLAVLPGVRAMRDCTRGGLGTTLCEWAEGTGL 230

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           GIE+ E+++P+   V  VC++LG D L+ A EG  +IA   +  ++++  L +HP G  A
Sbjct: 231 GIEIDESSIPIDEEVSSVCDILGFDPLHLACEGCALIAYSPDDEDRIIEILRAHPSGIQA 290

Query: 301 ALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
             IG VVE     V +    G  R +D+P  E LPRIC
Sbjct: 291 TSIGTVVEGHPSMVGMRTKAGGMRVVDMPVGELLPRIC 328


>UniRef50_Q8NKU8 Membrane-bound NiFe hydrogenase n=1 Tax=Acidianus ambivalens
           RepID=Q8NKU8_ACIAM
          Length = 339

 Score =  302 bits (774), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 124/342 (36%), Positives = 183/342 (53%), Gaps = 13/342 (3%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSY 60
           N IQ++HG+GG+  QQL+  LF        L   +    +D     A   + L  +TDS+
Sbjct: 4   NKIQISHGNGGKETQQLLQRLFFSRLPLE-LKRVKGGVGIDYPDDGAVLQNNLVVATDSH 62

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            ++P FFPGG+IG LA+ GT NDV + GA P  +    ++ EG P++ L+ +  SM E  
Sbjct: 63  TVNPYFFPGGDIGYLAVSGTLNDVIMMGAKPIAMLDSIVVSEGFPIDDLEKITGSMIELL 122

Query: 121 RAAGIAIVTGDTKVVQRGAV-DKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
           +   I +V GD KV++  A+ + + INT G+G +          +  GD ++V+G +G H
Sbjct: 123 KKYNIPLVGGDFKVIEETAMKNSIIINTVGLGVVETGSPI-VDAIKPGDKIIVTGPVGVH 181

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAAC 238
           GA I  +  Q  +   L SD   L  L++      G V A RD TRGG+ A ++E+A   
Sbjct: 182 GAVIAAM--QYNISTNLKSDVRPLFELLEVFSKFKGYVHAARDPTRGGLAATLNEWAQLT 239

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
           G  I + EA +PV   V+ + E+ GLD LN A+EG  V+AV+ N  + VL  L S  LG 
Sbjct: 240 GNVIVIEEAKVPVLEDVKAITEVTGLDPLNLASEGVGVLAVDSNVEDDVLETLKS--LGF 297

Query: 299 DAALIGEVVERKG----VRLAGLYGVKRTLDLPHAEPLPRIC 336
           + A IG VVE K     V      G  + L++P  + +PRIC
Sbjct: 298 EPASIGYVVEPKSEKGIVVAKTAVGGAKILEMPTGDIVPRIC 339


>UniRef50_C5CEU2 Hydrogenase expression/formation protein HypE n=1 Tax=Kosmotoga
           olearia TBF 19.5.1 RepID=C5CEU2_KOSOT
          Length = 326

 Score =  302 bits (773), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 112/336 (33%), Positives = 180/336 (53%), Gaps = 18/336 (5%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L H SG +  + L      +   +  ++ + D   L+             +TDS+ I 
Sbjct: 6   ITLHHNSGKKQFKLL--KHIEKLLGSTLVSTENDSGFLEEVVDT-------VTTDSFTIS 56

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+FFPGG+IGKL++CG+ ND+ ++GA P+Y++   +LEEG     L  ++ S+ +     
Sbjct: 57  PVFFPGGDIGKLSVCGSINDLVMTGAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELDEN 116

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G+ I+ GDTKV++ GA+DK+ INT  +G +        + +   D+++++G +G HGA I
Sbjct: 117 GVKIIAGDTKVMEHGALDKIVINTTCLGEVLYEK-LCVKRIETNDLIIITGPIGLHGAAI 175

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
           +  R+   +D    SDC VLT L+  ++ +  V A+RD TRGG+  +++EF+ +      
Sbjct: 176 MAERKGFQID--FQSDCRVLTKLLAVIKGLR-VHAMRDPTRGGLAQILNEFSHSTKRNFA 232

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + E  LP+   V+ V E+LG+D L  A EG  VI      A+ +L  L +   G D + I
Sbjct: 233 IYEDKLPIPGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNA--GFDPSTI 290

Query: 304 GEV---VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           G V   +ER  + L    G KR L +   E  PRIC
Sbjct: 291 GFVGGIIERPLLILKTRNGAKRVLPMLVEELTPRIC 326


>UniRef50_A5EUI7 Hydrogenase expression/formation protein n=4 Tax=Proteobacteria
           RepID=A5EUI7_BRASB
          Length = 346

 Score =  301 bits (770), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 148/335 (44%), Positives = 199/335 (59%), Gaps = 4/335 (1%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG+GG+ M+QLI  LF+    N  L    D A L     +  G     +TD + +
Sbjct: 15  RVSLAHGNGGRRMRQLIEELFVRHLGNALLDTDADAAALP---PLPTGATPMITTDGFTV 71

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DPL FPGGNIG LA+ GT ND+AVSGA P YL+    LEEGL +  L  +  SMA  A  
Sbjct: 72  DPLEFPGGNIGSLAVHGTVNDLAVSGAEPLYLTLNCFLEEGLDLGLLDRLTASMAAAATE 131

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ +V GDTKVV+RG    +++ T+G+G   A +  G   + AGD +LVSG +GDHG  
Sbjct: 132 AGVKVVAGDTKVVRRGEGGGVYLATSGVGLRRAGLDLGLGRIAAGDHILVSGPVGDHGTA 191

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           +L  R Q GL G+LVSD A + P+ + L D+PG++ +RD TRGG+  V HE     G GI
Sbjct: 192 VLLARGQFGLRGDLVSDSASVLPVTRALVDVPGLRFMRDPTRGGLATVAHEIVRHTGMGI 251

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            LSE A+P++  VR VCE+LG + L  A+EG++V  V+  +A   LAA+       DA  
Sbjct: 252 RLSEPAIPIRDQVRAVCEMLGYNPLYLASEGRVVAVVDPASAPAALAAMRGPGQSPDAVE 311

Query: 303 IGEV-VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           IG V  E   V L    G +R ++   A+PLPRIC
Sbjct: 312 IGTVGCEEPYVVLETEIGGERLIEELEADPLPRIC 346


>UniRef50_B1YBW5 Hydrogenase expression/formation protein HypE n=7 Tax=Archaea
           RepID=B1YBW5_THENV
          Length = 366

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 127/347 (36%), Positives = 184/347 (53%), Gaps = 19/347 (5%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDL-----AQLVAEGDRLAFSTD 58
           I+L+HGSGG    +++  LF+       L +      LD      A  +A+G  L  + D
Sbjct: 25  IKLSHGSGGVETSEIVEKLFLRRLP-EGLKKVAGGLGLDFPDDAAAIPMADGRYLVVTVD 83

Query: 59  SYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
           +Y ++P FFPGG+IG LA  G+ NDV + G  P  +    I EEGLP ETL  VV S   
Sbjct: 84  AYTVNPPFFPGGDIGMLAASGSINDVLMLGGRPLAMLDSIIAEEGLPYETLDRVVKSFLS 143

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD 178
              A G+A++ GD KV+ +G +DK+ I T G+G     I         GD ++VS  +GD
Sbjct: 144 VLEAEGVALIGGDFKVMPKGQLDKIVITTVGIGVADRIIV---DKPRHGDKIVVSDFVGD 200

Query: 179 HGATILNLREQ---LGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHE 233
           HGA IL L+          +L SD   LT L+  L +  G  + A RD TRGG+  V+++
Sbjct: 201 HGAVILMLQMGDVDKPEQLQLKSDVKPLTKLMVPLVEKYGEYIHAARDPTRGGLAMVLND 260

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS 293
           +A A G  I + E +LPV+P V     +LG+D L  A+EG  V+AV+   AE+V+  +  
Sbjct: 261 WAKAGGGVIVVEEESLPVRPEVASYAGMLGIDPLYLASEGAAVLAVDPAVAEEVVKFMRG 320

Query: 294 HPLGKDAALIGEVVE----RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
               ++A ++GE  E    R  V L  + G  R L+ P  + +PRIC
Sbjct: 321 LGF-QNARVVGEFREARQHRGYVLLKTVAGGLRILEPPRGDIVPRIC 366


>UniRef50_A3Z0T5 Hydrogenase expression/formation protein; HypE n=1
           Tax=Synechococcus sp. WH 5701 RepID=A3Z0T5_9SYNE
          Length = 343

 Score =  285 bits (729), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 144/323 (44%), Positives = 186/323 (57%), Gaps = 10/323 (3%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGK 74
            Q+L+  + + A          D   LD A L  E   LAFSTD +V+ PL FPGG+IG 
Sbjct: 30  SQRLLEQVILPALG------ATDGVLLDAASLTTEAGELAFSTDGHVVRPLEFPGGDIGA 83

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
           LA+ GT ND+A+ GA P  LS G ILEEGLP+  L  V++S A  A   G+++VTGDTKV
Sbjct: 84  LAVFGTVNDLAMLGATPLALSLGLILEEGLPLSILSRVLSSAAAAAARCGVSVVTGDTKV 143

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
           V+RG  D LF+ TAG+G IPA +  G   + +GD +LVSG LG HG  IL  RE+LG   
Sbjct: 144 VERGKADGLFMTTAGIGRIPAGVSIGPSAIRSGDAILVSGDLGRHGLAILAAREELGFST 203

Query: 195 ELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
            L SD A L   +Q L      + ALRD TRGG+ A +HE     G G  + EA +PV  
Sbjct: 204 SLESDLAPLHGSVQALLAAGLELHALRDLTRGGLAAALHELCRDAGLGGLVHEAVVPVHA 263

Query: 254 AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           AV   CELLGLD L  A+EG+ V+ +  + A+  L  L        AA+IG +   + + 
Sbjct: 264 AVATACELLGLDPLTMASEGRFVMMLPASQAQDALKLLRHEQ--SSAAVIGRI-GGEALL 320

Query: 314 LAGLYGVKRTLDLPHAEPLPRIC 336
           L    GV+R L+L   E LPRIC
Sbjct: 321 LETSLGVRRPLELGRGELLPRIC 343


>UniRef50_D2RDT5 Hydrogenase expression/formation protein HypE n=3
           Tax=Archaeoglobaceae RepID=D2RDT5_ARCPR
          Length = 344

 Score =  275 bits (705), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 115/350 (32%), Positives = 181/350 (51%), Gaps = 25/350 (7%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I+   G+GG+ M + +    +  F +  L E       D     ++ D   F+TDSYV+ 
Sbjct: 3   IRREDGAGGKYMAEFLKKHIISRFGDNRLGEISLADMDD----SSDFDGYVFTTDSYVVS 58

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P  F GG+IG LA+CGTAND+AV GA P  +S   I++EG  +   + ++  +    +  
Sbjct: 59  PPIFRGGSIGSLAVCGTANDLAVMGAKPYAMSLALIIQEGFKVSDFEKIMNDVERWVKEL 118

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH----------------WGAQTLTAG 167
            + ++TGDTKVV      ++  NT+G+G   + +                      L  G
Sbjct: 119 DVKLITGDTKVVSANV--EIIANTSGIGIRNSALDHNISVVKEYRDYPYNWVRDCGLREG 176

Query: 168 DVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGV 227
           D ++VSG + DH   I+  RE    D ++ SD   +   ++   ++ G+ A++D TRGG+
Sbjct: 177 DAIIVSGCVADHAVAIMLSRE-FDFDIDVQSDVYPVWLFVKEALEVGGITAMKDPTRGGL 235

Query: 228 NAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQV 287
              ++E A   G GI + E  +P++  V+G CE+LGLD L+ ANEGK+V+ V  + AE V
Sbjct: 236 ANALNELAEKSGVGIYIEEERIPIREEVKGFCEVLGLDPLSMANEGKVVMGVVEDMAEDV 295

Query: 288 LAALHSHPLGKDAALIGEVVE-RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           L ALH     K A +IG      + V +    G K+ L  P A+P+PR+C
Sbjct: 296 LKALHKAGQ-KYAEIIGYATSEFEEVVVETEIGTKKVLPPPTADPIPRVC 344


>UniRef50_A3DKG6 Hydrogenase expression/formation protein HypE n=1
           Tax=Staphylothermus marinus F1 RepID=A3DKG6_STAMF
          Length = 346

 Score =  274 bits (701), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 106/346 (30%), Positives = 175/346 (50%), Gaps = 19/346 (5%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDL----AQLVAEGDRLAFSTDS 59
           I   HGSGG    ++I  L +       L +  D   LD+    + +      +  STD+
Sbjct: 7   ITTVHGSGGFETLEIIEKLIVHRVP-ENLRKVLDGVGLDVLDDGSSMRIGNTHIVISTDN 65

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           + + PLFFPGG+IG LA+ G  ND+ + GA P     G I+EEG P + L  ++ SM + 
Sbjct: 66  FTVKPLFFPGGDIGHLAVSGVLNDLVMMGARPIAFMDGIIVEEGFPRDDLDRILESMIKL 125

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
            +   +A++ GD KV+ + ++D L I+  G+G     I      +  GD ++V+G + +H
Sbjct: 126 LKENNVALIGGDFKVMPKKSLDGLIISGTGIGLAEKPII---DKIKPGDKIIVTGPIAEH 182

Query: 180 GATILNLREQLGLDGE-LVSDCAVLTPLIQTLRD--IPGVKALRDATRGGVNAVVHEFAA 236
           GATIL  +  +    + L SD   L   +  + +     + A RD TRGG++ V++E+  
Sbjct: 183 GATILAAQLGMLEQAQGLRSDTRPLVKTVLPILEKYRDHIHAARDPTRGGLSIVLNEWVR 242

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
                I ++ + +P++  VR   + LG+D L  A EG  +++V+   A++++  LH    
Sbjct: 243 GTKYTIVINRSTIPIRDEVRQFLDALGIDPLGVAGEGLAILSVDNEVADEIVEELHRRGE 302

Query: 297 GKDAALIGEVVERKGVRLA------GLYGVKRTLDLPHAEPLPRIC 336
              A +IGEV+  +   LA         G K  +  P+A  LPRIC
Sbjct: 303 -PYATIIGEVIVPEEEYLAGRVIAITEVGGKVVVQ-PNALNLPRIC 346


>UniRef50_B6YVE6 HypE n=9 Tax=Thermococcaceae RepID=B6YVE6_THEON
          Length = 330

 Score =  272 bits (695), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 82/334 (24%), Positives = 141/334 (42%), Gaps = 19/334 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAE-QEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+   + +  +       P      +    +D   +      L  STD     P+     
Sbjct: 5   GKIPPEKLREIVFNRLGAPGERVIAKSDLGVDATAIDFGSSVLVASTD-----PITGAEE 59

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            IG  A+   ANDVA  GA P++     +L E      L  ++  + E+A   G+AIV G
Sbjct: 60  KIGFYAVHINANDVATFGAKPKWFLVSILLPENSDDALLVKIMDELHESASKLGVAIVGG 119

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T+V     +D+  +    +G +P      +     GD ++++   G  G  I+      
Sbjct: 120 HTEVTP--GLDRPIVAGTMLGEVPKEKLVTSNGAKPGDAIILTKWAGLEGTAIIASERGK 177

Query: 191 GLD----GELVSDCAVLTPLIQTLRDI-----PGVKALRDATRGGVNAVVHEFAAACGCG 241
            L+     E V     L  +I  + D       GV A+ D T GGV   +HE A A   G
Sbjct: 178 ELEKAFGKEFVEKAQSLIEMISVVEDALTANEIGVNAMHDPTEGGVANGLHEMADAAKLG 237

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             +    +P++     +CE   L+ L   + G L+IA  +  A+ +++AL     G +A+
Sbjct: 238 FRVYAERIPIRKETLKICEFYDLNPLALISSGALMIAAPKEKADSIISALKRK--GINAS 295

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           +IGE +E K  R+    G ++ L+ P ++ L ++
Sbjct: 296 VIGEFLEDKESRVMVDNGKEKPLERPESDELWKV 329


>UniRef50_B8D3R7 Hydrogenase expression/formation protein HypE n=1
           Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D3R7_DESK1
          Length = 349

 Score =  271 bits (693), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 109/347 (31%), Positives = 176/347 (50%), Gaps = 21/347 (6%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQA--RLDLAQLVAEGD-RLAFSTDSY 60
           I   HG+GG     +I  L          +         LD    +  G+  + F++D+Y
Sbjct: 10  ITTLHGAGGIESWNIIEKLIRGRVPRDLWSTPGGAGLDVLDDGSYIRIGESYIVFASDAY 69

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + PLFFPGGNIG+L   G  ND+ + GA P       ++EEG  +  L+ +V SM +T 
Sbjct: 70  TVKPLFFPGGNIGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELEDIVDSMVKTL 129

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
               +A++ GD KV+ RG+VD + I+   +G   +       ++  GD ++V+  + +HG
Sbjct: 130 VENNVALIGGDFKVMPRGSVDGVVISGFAIGV--SGKPPVVDSIKPGDKIIVTNYIAEHG 187

Query: 181 ATILN-----LREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFA 235
           +TIL      L +  GL  ++      + P+I+  RD   + A RD TRGG+ A+++E++
Sbjct: 188 STILAAQLDMLNDAPGLKSDVKPLVKTVLPVIEEYRDY--INAARDPTRGGLAAILNEWS 245

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
            + G  I + +  +PV+  V    E+LG+D L  A+EG  V++V    A++V+ AL  + 
Sbjct: 246 RSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEALRRN- 304

Query: 296 LGKDAALIGEVVE------RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            G++  +IGEVVE      R  V      G    +  P A  LPRIC
Sbjct: 305 -GENPYIIGEVVEPRSRELRGRVVALTEVGGLTII-PPQAYNLPRIC 349


>UniRef50_A1S0T2 AIR synthase related protein domain protein n=2 Tax=Archaea
           RepID=A1S0T2_THEPD
          Length = 335

 Score =  250 bits (640), Expect = 4e-65,   Method: Composition-based stats.
 Identities = 88/334 (26%), Positives = 130/334 (38%), Gaps = 19/334 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+     +  L                   D A +      L    D     P+     N
Sbjct: 7   GKLTYGELEELLSRLRRQDASVLLGPAIGEDAALIDLGDKVLVVHAD-----PITGAVSN 61

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           IG L++  +ANDVA  G  PR+L    +L EG   + L  +   + + A   G  IV G 
Sbjct: 62  IGWLSVHVSANDVATRGVQPRWLVTVVLLPEGAGQDVLWDIAGQLRKAADEIGATIVGGH 121

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE--- 188
           T+      +D+  + T  MG               GD L+++   G  G  IL       
Sbjct: 122 TEFTP--GLDRPILVTTAMGVGGKGEVLATSRARPGDALILTKGAGIEGTAILATELYDE 179

Query: 189 -QLGLDGELVSDCAVLTPLIQTLRDI------PGVKALRDATRGGVNAVVHEFAAACGCG 241
               +D E++         +  ++D        GV A+ D T GGV   + E A A   G
Sbjct: 180 LSRKVDREVLERAKSFIYEVSVVKDALTAVRAGGVHAMHDPTEGGVLGGLQEMAIAANAG 239

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           + + E  +PV+   + VC  LG+D L   + G L+IAVE + A  V+ AL     G  AA
Sbjct: 240 LVVEEEKIPVREETKAVCRALGVDPLRLISSGSLLIAVEGSRARDVVDALSRE--GIPAA 297

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           +IG + E     L    G    L+ P  + L RI
Sbjct: 298 VIGRLTEGSERILVKRGGEIVDLNEPVVDELWRI 331


>UniRef50_B7R791 AIR synthase related protein, C-terminal domain n=2
           Tax=Thermoanaerobacteraceae RepID=B7R791_9THEO
          Length = 348

 Score =  242 bits (618), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 79/309 (25%), Positives = 135/309 (43%), Gaps = 27/309 (8%)

Query: 35  QEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYL 94
            ED + +D  + VA       STD     P+       G L++  + ND+A  GA P  +
Sbjct: 50  GEDSSIIDFGEYVA-----VLSTD-----PITAADKLSGFLSVIISCNDLAACGAEPIGI 99

Query: 95  SCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIP 154
               +L EG   + LK ++  + + ++  GI ++ G T+V Q  AV+K  I+T  +G   
Sbjct: 100 LTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGGHTEVTQ--AVNKPVISTTAIGIAR 157

Query: 155 ANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ----LGLDGELVSDCAVLTPLIQTL 210
              +  ++    GD ++V+  LG  G  IL    +         + V         I  +
Sbjct: 158 KGKYITSKGAKIGDDVIVTKALGLEGTAILATDYEDLLIKHFGKDFVLKAQSFINEISVI 217

Query: 211 RDIP-----GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD 265
            +       G  A+ D T GGV    +E + A G GIE+ E  LP +   + +C+  GL+
Sbjct: 218 EEGLIASQNGANAMHDITEGGVLGATYEISEASGLGIEIYEEKLPFRRETKEICKFFGLN 277

Query: 266 ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLD 325
            L   + G ++I        +++ AL     G  A +IG++V ++G  L    G +  L 
Sbjct: 278 PLKLISSGSMLITA--EDGNRIVKALSEK--GIQATIIGKIV-KEGRYLITSSGKEEIL- 331

Query: 326 LPHAEPLPR 334
            P  + + R
Sbjct: 332 PPEKDEIYR 340


>UniRef50_B8I2N9 AIR synthase related protein domain protein n=6 Tax=Clostridium
           RepID=B8I2N9_CLOCE
          Length = 330

 Score =  240 bits (612), Expect = 7e-62,   Method: Composition-based stats.
 Identities = 77/328 (23%), Positives = 142/328 (43%), Gaps = 29/328 (8%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAIC 78
           IN+   E    P + E       D A +  +      STD     P+   G N G+LA+ 
Sbjct: 19  INTFRKEVIMRPGIGE-------DCAAIEFDKYACVMSTD-----PITAAGKNAGRLAVH 66

Query: 79  GTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRG 138
            + ND+A SG  P  L    +   G     L+ ++  + ETA    + I+ G T+V    
Sbjct: 67  ISCNDIASSGVEPLGLMVTILCPVGTTETELEHLMDQVCETAGQLNVEIIGGHTEVTP-- 124

Query: 139 AVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGEL-V 197
           AV+K+ ++T  +G    +    +     GD ++++ + G  G  I+    +  L   +  
Sbjct: 125 AVNKIILSTTCVGKSLKDKIISSSGAKPGDSVILTKSAGLEGTAIIAGDFEEELAEVMNK 184

Query: 198 SDCAVLTPLIQTLRDIP--------GVKALRDATRGGVNAVVHEFAAACGCGIELSEAAL 249
           ++      LI  +  +P        GV ++ D T GGV     E A A   G+ + + ++
Sbjct: 185 NELQYAKSLINAISVVPEGVLAGRFGVTSMHDITEGGVLGAAWEIAEASSTGVTIKKDSI 244

Query: 250 PVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
           PV+P  R +C+  G++ L   + G ++I       E ++  L  +     A++IG + + 
Sbjct: 245 PVEPVTRHICDHFGINPLRLISSGCMIITC--KDGEGLVRLLGENN--IKASIIGTITQN 300

Query: 310 K--GVRLAGLYGVKRTLDLPHAEPLPRI 335
           K   + ++   G    ++ P A+ L +I
Sbjct: 301 KTGRLLISEKEGTSENIEAPGADELYKI 328


>UniRef50_C7G8J7 Hydrogenase maturation factor n=4 Tax=Clostridiales
           RepID=C7G8J7_9FIRM
          Length = 331

 Score =  239 bits (611), Expect = 8e-62,   Method: Composition-based stats.
 Identities = 73/328 (22%), Positives = 133/328 (40%), Gaps = 22/328 (6%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFPGGNIGKLA 76
           L  S+F +                D A + +AE + L  STD     P+     +IG LA
Sbjct: 15  LKRSVFKQIHTKRPEVVLGAGVGEDCAAVKLAEDETLVMSTD-----PITGTAQDIGTLA 69

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           I  TAND+A +GA P  +    +L   +    L+ ++  +      AG+ ++ G T++  
Sbjct: 70  IQITANDLASAGAEPVGVLLTVLLPPEIEEPDLREMMQQVEAACAKAGVQVMGGHTEIT- 128

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG----L 192
              V++  I+  G+G +             G  +LV+  +G  G +I+   ++       
Sbjct: 129 -AVVNQPVISVCGVGKVKDGCLISTGGAKPGMDILVTKWIGIEGTSIIAKEKEKDLLTRF 187

Query: 193 DGELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
               + +   L   +  L +       GV A+ D T GG+   + E A A G G+E+   
Sbjct: 188 SAPFIENAKKLDVYLSVLSEAAVAVRSGVSAMHDVTEGGIFGALWEMAEASGVGLEIDLK 247

Query: 248 ALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
            +PV+     +CE  G++     + G +++A        ++  L     G  A +IG+  
Sbjct: 248 KIPVRQETIEICEFFGINPYELISSGSMLMAAADGNL--LVNELKKA--GIPATIIGKAT 303

Query: 308 ERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
                 L      +R L+ P  + L ++
Sbjct: 304 AGNDRVLLNED-ERRFLEPPKTDELYKV 330


>UniRef50_C3N301 AIR synthase related protein domain protein n=9 Tax=Sulfolobus
           RepID=C3N301_SULIA
          Length = 402

 Score =  238 bits (609), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 75/336 (22%), Positives = 129/336 (38%), Gaps = 20/336 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQ-EDQARLDLAQLVA-EGDRLAFSTDSYVIDPLFFPG 69
           G+  + L N +                Q  +D A +   +G  L   TD   I P F   
Sbjct: 65  GKINEDLFNKVIYPHLGEKRTEVLVGPQHGVDTAAIDLQDGRILVVKTDPVFIVPQFG-F 123

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
                 A+   A+DV  SG  P+Y      L   +  +  + +   + E  +   + +V 
Sbjct: 124 KKAAWFAVHILASDVMTSGIPPQYAVIDVNLPPKIKDDEFEEMWIGIHEALKEIEVMVVG 183

Query: 130 GDTKVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR- 187
           G T V +    D   +      G            +  GD ++++         +L    
Sbjct: 184 GHTGVYE--GTDYPMVGGFTMFGIGEKEKLGMPSKVRVGDSVIMTKGPAIEATGLLTNLY 241

Query: 188 ---EQLGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACG 239
               +  LD E  ++   +   +   +D       G+  + DAT GGV   + E A A G
Sbjct: 242 PEYFKQRLDKETFNEAYNIYWKMSCWKDGLIASRIGIHLMHDATEGGVFGALTEVARASG 301

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            G+ + E  L +  AVR V  L+ +D     +EG ++I  ++     V  AL     G +
Sbjct: 302 KGMNVYEDKLFINSAVREVTRLVNIDPWISISEGTMIIVTDKGK--DVREALIKE--GIE 357

Query: 300 AALIGEVVERKG-VRLAGLYGVKRTLDLPHAEPLPR 334
           A +IGE+V++ G V+L    G +  ++ P  +P  R
Sbjct: 358 AEIIGEIVDQSGDVKLVKKDGSRVKIEHPLEDPFWR 393


>UniRef50_B0KA39 AIR synthase related protein domain protein n=10 Tax=Clostridia
           RepID=B0KA39_THEP3
          Length = 331

 Score =  237 bits (605), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 73/308 (23%), Positives = 131/308 (42%), Gaps = 27/308 (8%)

Query: 35  QEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYL 94
            ED + +D  + VA       STD     P+       G L++  + ND+A  GA P  +
Sbjct: 33  GEDSSIIDFGEYVA-----VLSTD-----PITAAEKLSGFLSVIISCNDLASCGAKPIGI 82

Query: 95  SCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIP 154
               +L EG     L  ++  + + A+   I ++ G T++     V+K  I+T  +G   
Sbjct: 83  LSTILLPEGSDESVLHNLMEEIDKAAKKLNIEVLGGHTEITT--TVNKPIISTTAIGMAK 140

Query: 155 ANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ----LGLDGELVSDCAVLTPLIQTL 210
              +   +    GD ++V+  LG  G  IL    +       D + +         I  +
Sbjct: 141 KGEYITTKGAKIGDDVIVTKALGLEGTAILATDYEDLLLKRYDKDFILKAQSFINEISVI 200

Query: 211 RDIP-----GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD 265
            +       G  A+ D T GG+    +E A A G GIE+ E  LPV+P  + +C   G++
Sbjct: 201 EEGLIAAQNGANAMHDITEGGILGAAYEIAEASGLGIEIYEEKLPVRPETKEICRFFGIN 260

Query: 266 ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLD 325
            L   + G ++I       ++++ +L     G  A +IG+++ ++G  L    G K  + 
Sbjct: 261 PLKLISSGSMIITAS--DGDKIVKSLSEK--GIQATIIGKII-KEGKYLITSKG-KEEIT 314

Query: 326 LPHAEPLP 333
            P  + + 
Sbjct: 315 PPERDEIY 322


>UniRef50_C7NS45 AIR synthase related protein domain protein n=1 Tax=Halorhabdus
           utahensis DSM 12940 RepID=C7NS45_HALUD
          Length = 345

 Score =  237 bits (604), Expect = 6e-61,   Method: Composition-based stats.
 Identities = 86/331 (25%), Positives = 133/331 (40%), Gaps = 27/331 (8%)

Query: 20  NSLFMEAFANPWLAEQED------QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIG 73
           +  F + +  P L    D      Q  +D       G  LA +TD   I P         
Sbjct: 10  DREFFDEYIYPRLGADRDDVRLQPQHGVDFGVADVGGQALAMATDPVFIVPA-AGFERAA 68

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A     +DVAVSG  P YLS  F L   +  E  + V  +  + A   G +IVTG T 
Sbjct: 69  WFAFHILFSDVAVSGLDPAYLSVDFNLPPEITDEQFETVWETFDQEAAELGASIVTGHTG 128

Query: 134 VVQRGAVDKLFINTAGMGAIPA-NIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
             +    +   +  A   A    +          GD ++V+         +L++     +
Sbjct: 129 --RYAGCNYPMVGGATTVATGDFDDLVTPDGARPGDRVIVTKGPAIEATGLLSVHFDSLM 186

Query: 193 DGELVSD--------CAVLTPLIQTL--RDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           DGE+ +D           ++P+ + +       V A+ DAT GGV   + E A +   G 
Sbjct: 187 DGEVPADEIQAAKDRFYDMSPIQEAMVASAAGPVTAMHDATEGGVYGGLFEMARSADVGF 246

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+    +PV+P V   C+   +D     +EG L+  V+ + A  VL+AL S   G  AA 
Sbjct: 247 EIERDRIPVQPGVEAACDFFDIDPWISISEGTLLATVDPDGASDVLSALKSE--GIPAAD 304

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
            G VVE  G+ + G     + +D P  +P  
Sbjct: 305 AGRVVEGSGLTVDG-----QAVDHPGKDPYW 330


>UniRef50_A8MLK1 AIR synthase related protein domain protein n=3 Tax=Clostridiaceae
           RepID=A8MLK1_ALKOO
          Length = 330

 Score =  237 bits (604), Expect = 6e-61,   Method: Composition-based stats.
 Identities = 68/333 (20%), Positives = 134/333 (40%), Gaps = 20/333 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQ-EDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+   +++  +      N             D A +         STD     P+     
Sbjct: 4   GKVPTEVLKEVIFSNLKNRRPEVLVRPNIGEDCAVVDFGDYVCVMSTD-----PITGAAK 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IG LA+  + ND+A SG  P  +    +       E L  V++   + A +  + I+ G
Sbjct: 59  DIGSLAVHISCNDIASSGVEPLGIMLTIMAPPHTTKEDLSLVMSEANKAAASVNVEIIGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T++    AV+++ I+   +G         ++     D + ++   G  G  I+    + 
Sbjct: 119 HTEITD--AVNRMIISATAIGRQLKEKLVLSEGAKIDDAVFMTKYTGLEGTAIIARDLEE 176

Query: 191 GLDGEL----VSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGCG 241
            L  ++    +         I  +++       GV ++ D T GG+   + E   A G G
Sbjct: 177 KLKEKISDATIQTAQEFLKDISVVKEGITAGEVGVHSMHDVTEGGIFGALWELGEASGIG 236

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IE+ E  +P++P    +C  L +D +   + G +V+ + ++  E ++ A     L     
Sbjct: 237 IEIYEDQIPMRPETLEICHYLSIDPMRLISSGVMVMTIAQDKKEALMEAFKRENLIL--T 294

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
            IG +VE+  + ++   G+ R LD P  + L +
Sbjct: 295 EIGRMVEKDRIIISAAKGI-RALDPPDVDELYK 326


>UniRef50_A8ZNV6 Hydrogenase expression/formation protein HypE n=2 Tax=Bacteria
           RepID=A8ZNV6_ACAM1
          Length = 339

 Score =  235 bits (600), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 66/334 (19%), Positives = 123/334 (36%), Gaps = 22/334 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+    L+  L  +   +            D A +          +D     P+ F   +
Sbjct: 9   GKLPSHLLAHLLSQTPIHDPQVLLGPGIGHDCAVVDGGAKLWVIKSD-----PITFVTDD 63

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETL-KAVVTSMAETARAAGIAIVTG 130
           IG   +   AND+A +GA PR+L    +L E     TL + +   +    +   ++++ G
Sbjct: 64  IGWYVVQINANDIATTGATPRWLMATILLPEQRTTATLAERIHQQIYTACQEINVSLIGG 123

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T++     +D+  +    +G +  +     +    GD +L++ ++      IL      
Sbjct: 124 HTEITY--GIDRPIVVGTLIGEVARDSLITPRGAKPGDRILLTKSVPIEATAILAREYSE 181

Query: 191 GLDGELVSD------CAVLTPLIQTLRDI------PGVKALRDATRGGVNAVVHEFAAAC 238
            +   L SD        +  P I  LRD         V A+ D T GG+ A + E A A 
Sbjct: 182 QISQALTSDELTQARGYLYKPGISVLRDAQLANQAGQVSAMHDPTEGGLLAALWELAQAS 241

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
            C + +    +P+      +C +  +D L     G L++   +  A  +   L++   G 
Sbjct: 242 NCQLVIDLEKVPISDLSAHICRVFKIDPLAAIASGALLLTAPQRDAPSICRTLNTS--GI 299

Query: 299 DAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
               IG+V        +     K  L  P  + +
Sbjct: 300 PCCEIGDVQSGNATVWSRTALEKERLPCPSRDEI 333


>UniRef50_Q97BE7 Hydrogenase expression formation protein HypE n=3 Tax=Thermoplasma
           RepID=Q97BE7_THEVO
          Length = 374

 Score =  230 bits (588), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 69/341 (20%), Positives = 141/341 (41%), Gaps = 29/341 (8%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQA----RLDLAQL-VAEGDRLAFSTDSYVIDPLF 66
           G+  ++      +           ED+      +D   + +  G  +A +TD +  DP+F
Sbjct: 32  GKLDRKFFTESILRYTGY---RRPEDKVPPKNGVDTGIISIGNGKVMAVTTDPFYFDPVF 88

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
               +    A    A+D+  +G  P Y++    L   +  E +  +  ++ E A     +
Sbjct: 89  G-YEDSAWFAYHILASDITTAGVYPEYMTVDLNLPISISNEEIARMWKTVHEEAYKYKTS 147

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL-- 184
           I+TG T          +       G    + +        GD+++++ T G   A++L  
Sbjct: 148 IITGHTARYANTGFPMVG-GATMFGFTDDDKYVTTAMARPGDIMIMTKTAGIEAASLLTR 206

Query: 185 ----NLREQLGLDG-----ELVSDCAVLTPLIQTLRD--IPGVKALRDATRGGVNAVVHE 233
               ++++ LG D      EL    + +   IQ +       + ++ DAT GG+   V+E
Sbjct: 207 IFPNHVKKNLGEDKYRYGFELFRKLSTVDEAIQAIEFGTRKAITSMHDATEGGLLGAVYE 266

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS 293
            A A G G+ + + A+ V   V+ +  L G+D L   +EG L++ ++   A++ +  L  
Sbjct: 267 VAEASGNGVSIDKEAIHVDDYVKEIHSLFGIDPLRSISEGTLLMTIDPEYADEFMKRLTK 326

Query: 294 HPLGKDAALIGEV-VERKGVRLAGLYGVKRTLDLPHAEPLP 333
              G D+ +IG++  + +G++          +  P  +P  
Sbjct: 327 S--GIDSYVIGKMTTKDEGIKFKD---GSEPIGEPEKDPFW 362


>UniRef50_C9L525 Hydrogenase maturation factor n=1 Tax=Blautia hansenii DSM 20583
           RepID=C9L525_RUMHA
          Length = 344

 Score =  230 bits (587), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 74/342 (21%), Positives = 137/342 (40%), Gaps = 27/342 (7%)

Query: 10  SGGQAMQQ-------LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
           +GGQ M+        LI S+  +                D A +  E   +         
Sbjct: 12  NGGQNMKIGKLPEPVLIRSVLKQVGHRRNEVLVGPAVGQDCAVMELEEGEVFV----LSC 67

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DP+     +IG  ++  TAND+A SGA P  +    +L        LK ++  + +T + 
Sbjct: 68  DPITGTTKDIGGHSVHITANDLAASGAEPVGIMLTMLLTPDTEEAQLKEIMQDVEKTCKE 127

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
             + ++ G T+V     V +  I+  G+G +         ++  GD ++V+  +G  G +
Sbjct: 128 LNMEVLGGHTEVTDV--VKQTLISLTGVGKMKKENVLTTASVKPGDDIVVTKWIGLEGTS 185

Query: 183 ILNLREQ----LGLDGELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHE 233
           I    ++           V         +  + +       GV A+ D T GGV   + E
Sbjct: 186 IAAKEKESLLLEHFAPPFVETAKKFDQYLSVIPEAKIAAEWGVSAMHDITEGGVFGALWE 245

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS 293
             +  G G+++    +P++     VCE+LGL+     + G ++IA +      ++  L  
Sbjct: 246 MGSGSGVGLDIDLKEIPIRQETVEVCEVLGLNPYILMSSGSMMIAAKDGYG--LVRKLKQ 303

Query: 294 HPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
              G +AA++G+  +     L       R LD P ++ L +I
Sbjct: 304 A--GIEAAVVGKATDGNDRILRNGE-DTRYLDKPQSDELYKI 342


>UniRef50_A4YFC4 AIR synthase related protein domain protein n=3 Tax=Sulfolobaceae
           RepID=A4YFC4_METS5
          Length = 332

 Score =  230 bits (587), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 68/332 (20%), Positives = 124/332 (37%), Gaps = 29/332 (8%)

Query: 19  INSLFMEAFANPWLAEQEDQARL------DLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI 72
           I+    +    P L ++ D+  +      D   +      L   TD   I P F      
Sbjct: 5   IDRKVFDEVIYPHLGKRLDEVIVPPLTGVDTGAIDLGDRVLVVKTDPVFIVPQFG-MKKA 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
              A+   A+DV  SG  PRY      L   +  E  + +   + E     G+ +V G T
Sbjct: 64  SWFAVHILASDVMTSGIPPRYALLDLNLPPSMTDEEFREMWVGIHEALLEIGVMVVGGHT 123

Query: 133 KVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR---- 187
              +   V+   +     +G            +  GD ++V+         +L       
Sbjct: 124 GRYE--GVNYPMVGGFTMIGIGEKEKLGHPSKVKPGDYVIVTKGPAIEATGLLTNLYPEF 181

Query: 188 EQLGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACGCGI 242
            +  +  +L  +   +   +   +D       G+  + DAT GG+   + E +   G  I
Sbjct: 182 FRERMRSDLFKEALDMYWKMSCWKDGLIASQVGIHMMHDATEGGLWNALVEISEVTGKRI 241

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            L    L + PAVR V  ++G+D  +  +EG +VI  ++   ++ L        G +A +
Sbjct: 242 NLVGERLFINPAVREVTRIVGIDPFSSISEGTMVIVTDKEKVKEELLR-----NGIEAEI 296

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           +G V   +GV + G     + ++ P  +P  R
Sbjct: 297 VGRVESGEGVYVDG-----KRIEKPSEDPFWR 323


>UniRef50_A5N2W0 HypE n=8 Tax=Clostridium RepID=A5N2W0_CLOK5
          Length = 329

 Score =  229 bits (585), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 65/306 (21%), Positives = 123/306 (40%), Gaps = 26/306 (8%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
               D + +         STD     P+     N G+LA+    ND+A  G  P  L   
Sbjct: 31  GIGEDCSVINFGDKECVVSTD-----PITGANINSGRLAVHINCNDIASCGIEPVGLLVT 85

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
            +L EG  +E +  ++  +++ A+   + I+ G T+V    AV+K+ I+   +G      
Sbjct: 86  ILLPEGASLEDINRLMGEISDEAKKLNVEILGGHTEVTS--AVNKIVISCTAIGKGDKGK 143

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATI-----------LNLREQLGLDGELVSDCAVLTPL 206
                     D ++ +  L   G +I           L  +E++      +   +V+   
Sbjct: 144 AVSTSGAKEKDDIVATKCLCLEGTSIIVNDYEDKLIGLLTKEEINEAKNYIKQISVVKEG 203

Query: 207 IQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
           I  L    GV ++ D T GG+   + E A A   G ++ +  LP+      +C    +D 
Sbjct: 204 I--LSGGFGVNSMHDITEGGILGALWEIAEASRVGFKVYKDKLPITKITEKICGHYLIDP 261

Query: 267 LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDL 326
           L   + G ++I   +   E+++  L +   G  A ++GE+ +     +    G +  +D 
Sbjct: 262 LKLISSGSMLITTPK--GEELVRMLENE--GIKACVVGEITKGGYKLI--CNGEEEEIDA 315

Query: 327 PHAEPL 332
           P  + L
Sbjct: 316 PGRDEL 321


>UniRef50_B8GHF5 AIR synthase related protein domain protein n=1
           Tax=Methanosphaerula palustris E1-9c RepID=B8GHF5_METPE
          Length = 345

 Score =  229 bits (584), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 77/336 (22%), Positives = 136/336 (40%), Gaps = 28/336 (8%)

Query: 19  INSLFMEAFANPWLAEQEDQ------ARLDLAQLVAEGDRLAFSTDSYVIDPLFF----P 68
           I++    +F        +        A +D   +    +R+    +    DP+F     P
Sbjct: 9   IDAATFASFLLHRTGAADPSVIVPPTAGIDAGVVDLGNNRVLIVAE----DPIFAIPNQP 64

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
               G   +   A+DVAV G  P+Y++   ++  G P +  + +V ++   A+  GIAIV
Sbjct: 65  YDLFGWHTVHIGASDVAVMGVKPQYMTYSLLMPPGTPDQDFRTIVDAIDLAAKDLGIAIV 124

Query: 129 TGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
            G T      A   +              +  +     GD +L++       A +L++  
Sbjct: 125 GGHTGYYPGFAAPTIG-GITVFAVAEKGEYITSAGARPGDDVLLTKGPAIETAALLSVLR 183

Query: 189 QLGLDGE----LVSDCAVLTPLIQTL------RDIPGVKALRDATRGGVNAVVHEFAAAC 238
           +  L  +    LV     L   +  +      R+   V A+ DAT GGV   + E AAA 
Sbjct: 184 ENELKAKYPAWLVKAAQDLCWQMSVVADAALAREAGEVTAMHDATEGGVIGGLFEIAAAS 243

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             G+ + EA +     VR VCE   LD L    EG L++  + ++++ ++  L     G 
Sbjct: 244 NTGMVIDEAQIIYPKEVRMVCEQFNLDPLASIAEGTLLLTADPSSSDAIIDLLTRS--GI 301

Query: 299 DAALIGEVVERKGVR-LAGLYGVKRTLDLPHAEPLP 333
             ++IG+V +  G R +  + G    L +P  +P  
Sbjct: 302 PVSVIGKVTDNPGERTIRRVDGTIEELHIPEQDPFW 337


>UniRef50_D1VUU5 Hydrogenase maturation factor n=1 Tax=Peptoniphilus lacrimalis
           315-B RepID=D1VUU5_9FIRM
          Length = 325

 Score =  226 bits (576), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 74/332 (22%), Positives = 130/332 (39%), Gaps = 19/332 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQAR-LDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+     +     +   +         +  +D A L   GD +  S     +DP+     
Sbjct: 4   GKVSNNDLEKYVFKNINSHRKEVLTKSSIGIDTAVLDFNGDLIVTS-----VDPITGANK 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           N+G LAI  + NDV+  GA P  +    +L     +E L  ++       R   + I+ G
Sbjct: 59  NLGYLAINISVNDVSCQGADPVGVLISILLPAESKLEDLNKIMEDADRACRQNNLEIIGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T+V    AV+K+ + T  +  +  N      ++  GDV+ VS  +G  G +I+   +  
Sbjct: 119 HTEVTD--AVNKIVLTTTVIARVNKNKMPKISSIKVGDVIAVSKDIGLEGTSIILEEKGN 176

Query: 191 GL--DGELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGCGIE 243
               + EL  +   +  L   LR+        VK + D T GG+   + E + A G GIE
Sbjct: 177 EFLSEDELRKESIDIKDL-SVLREAKIAVDFNVKYMHDVTEGGIYGALWECSEAIGKGIE 235

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           +    +PVK   + +     ++     + G +++   +   +    A            I
Sbjct: 236 VDNIKIPVKDVTKKIGSHYNINIYGLISSGSMLMVFNKEDFKAYKKACFEKN--IKITQI 293

Query: 304 GEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           GEV E     L    G K  +  P ++ L +I
Sbjct: 294 GEVTEENKKILID-NGKKIEIPEPASDELYKI 324


>UniRef50_A4XL04 AIR synthase related protein domain protein n=2 Tax=Clostridia
           RepID=A4XL04_CALS8
          Length = 325

 Score =  226 bits (576), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 59/332 (17%), Positives = 127/332 (38%), Gaps = 19/332 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+   +++     +                D A +  + D    + D     P+   G  
Sbjct: 4   GKIPIEILKEHVFDQKIERSDILLAPGIGEDSAAVDVKSDIAVITMD-----PITAAGSM 58

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
            G L++    ND+A +GA P  + C  ++      E    ++  + E  +   I ++ G 
Sbjct: 59  SGYLSVVVVCNDLAAAGAEPIGVLCTILMPPESSQEEFIQILRDIKEACKRFNIQLLGGH 118

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           ++V     V K  I + G G +  ++         GD ++++ TLG  G  IL   ++  
Sbjct: 119 SEVSP--IVTKPLIVSTGFGKVERDMLISTSKAKVGDKIIITKTLGIEGTFILYNEKKEK 176

Query: 192 LDGELVSD--------CAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
           L   L  +           L+ + + L       ++ D T GG+   ++E   A G G  
Sbjct: 177 LKTFLTPEEVSEIENYINKLSVVEEGLVARKYASSMHDITEGGLFGAIYEVCKASGKGAR 236

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + E  + +  +V+ +     L+     + G ++I  ++    +++  L     G D  ++
Sbjct: 237 IYEEKIVLSSSVKKISSFYNLNPYKLISSGSMLITTDKEN--ELICELKEK--GIDCYVV 292

Query: 304 GEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           GE++E   +      G    +D    + + ++
Sbjct: 293 GEIIEEPKIEFINSSGEITLIDELPIDEIYKV 324


>UniRef50_B9KYQ7 Hydrogenase expression/formation n=2 Tax=Thermomicrobia (class)
           RepID=B9KYQ7_THERP
          Length = 343

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 87/337 (25%), Positives = 138/337 (40%), Gaps = 24/337 (7%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+   QL+   F+   +             D A +  +  RL F +D     P+ F    
Sbjct: 9   GKLPPQLLAE-FLGNLSPDPSVLLGPGIGHDAAVIQIDTIRLVFKSD-----PITFATEA 62

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           IG  A+   ANDVA  GA PR+     +L EG      + ++  +A  A   G+++V G 
Sbjct: 63  IGWYALNVNANDVACLGARPRWFLATVLLPEGTTAHDAQVILDDLARAAERLGVSVVGGH 122

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR---- 187
           T++     +D+  +    +G +          +  GD LL+   +   G  +L       
Sbjct: 123 TEIT--VGLDRPIVAGTMIGELTTEYVLSPARVRPGDALLLVRGIAIEGTALLARECRQT 180

Query: 188 EQLGLDGELVSDCA--------VLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAA 237
            +  LD +L++ C          + P    L +  G  ++ L D T GG+   +HE A A
Sbjct: 181 LERMLDQDLLARCRRFLYEPGISIVPAATLLLERLGEDLRYLHDPTEGGLATGLHEVAVA 240

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
           CG G+ +SE A+ V P  R VC  LGLD L     G L+  V   + E  L  L  H   
Sbjct: 241 CGTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGALLAVVTPESVEHALDTLAQHD-- 298

Query: 298 KDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
             A  +G +    G R+      +R L +   + + R
Sbjct: 299 IPATQLGWLDPDPGRRVLIGSTGERPLPVFQVDEVAR 335


>UniRef50_Q2RKM3 AIR synthase related protein-like n=1 Tax=Moorella thermoacetica
           ATCC 39073 RepID=Q2RKM3_MOOTA
          Length = 528

 Score =  223 bits (570), Expect = 5e-57,   Method: Composition-based stats.
 Identities = 82/333 (24%), Positives = 134/333 (40%), Gaps = 24/333 (7%)

Query: 19  INSLFMEAFANPWLAEQEDQARL------DLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI 72
           ++  F      P     + +  +      D A L    + LA + D     P   P  + 
Sbjct: 5   VDDAFFRQAILPHTGAGDPEVVVGPRMGVDAAVLKIGEEYLAVAEDPIFPGPTTSP-DDF 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G + +   A+DVAV G  PR+++   +L  G P + +  +V S++  AR  GI IV G T
Sbjct: 64  GWITVHIGASDVAVMGIKPRFMTYSLLLPPGTPEDYIAGLVRSISTYARELGITIVGGHT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-- 190
                GAV    I    +      +         GD ++++       A ++        
Sbjct: 124 GFY--GAVTIPTIGGITVWGRGREV-VTPAGARVGDAVIITKGAAIEAAALVACELGEKL 180

Query: 191 ---GLDGELVSDCAVLTPLIQTLRDIP------GVKALRDATRGGVNAVVHEFAAACGCG 241
              G+  +LV+        +  + +        GV A+ DAT GG+   + E A A G G
Sbjct: 181 LAAGISPDLVARAKKRLREMSVVAEAGIAVEVGGVHAMHDATEGGLARGLWEVAEASGVG 240

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           + +  A +PV   +R VC+ +GL+     +EG LV+      A+ +LAA      G +AA
Sbjct: 241 LRIERARVPVPADIRAVCDYIGLNPYEVISEGTLVLTCAPEKADAMLAAFKEA--GIEAA 298

Query: 302 LIGEVVE-RKGVRLAGLYGVKRTLDLPHAEPLP 333
           +IG VV    G       G +  L  P  +   
Sbjct: 299 VIGRVVPAGAGRAWLEDDGREEQLLPPAVDRFW 331


>UniRef50_D1C5Z5 AIR synthase related protein domain protein n=7 Tax=Chloroflexi
           RepID=D1C5Z5_SPHTD
          Length = 359

 Score =  223 bits (569), Expect = 7e-57,   Method: Composition-based stats.
 Identities = 77/339 (22%), Positives = 130/339 (38%), Gaps = 22/339 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQ-EDQARLDLAQLVAEGDR-LAFSTDSYVIDPLFFPG 69
           G+   ++   +                Q  +D+  +   G R +A +TD + I P +   
Sbjct: 14  GKISPEVFEQVIKPRLGRHRPEVLVGPQHGVDVGIIDIGGGRVMAVTTDPFFIVPQYG-W 72

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
                 A+   A+D A SG  P Y      L   +  E L+A+  ++  T +  G+AIVT
Sbjct: 73  ERAAWFAVHILASDAATSGLPPTYFVVDLNLPRNITSEGLEALWHAVDATCKEIGMAIVT 132

Query: 130 GDTKVVQRGAVDKLFINTAGMGAI-PANIHWGAQTLTAGDVLLVSGTLGDHGATILNL-- 186
           G T        D   +  A + A+   + +        GD ++V+         +  +  
Sbjct: 133 GHTARYD--GTDYPMVGGAMVMAVGERDRYVTPTMARVGDAVIVTKGAAIEATGLFGVTF 190

Query: 187 --REQLGLDGELVSDCAVLTPLIQTLRDI----------PGVKALRDATRGGVNAVVHEF 234
             R       E+          +  ++D            GV A+ DAT GGV   ++E 
Sbjct: 191 PDRIAAAYGQEIARQAEETFYQMSVVKDAMTAVEVGVRDAGVTAMHDATEGGVWGGLYEI 250

Query: 235 AAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSH 294
           A A G G+ + + A+ V PA + VC+L G++     +EG L+I      A  VL  L   
Sbjct: 251 AVASGVGMVVEQNAIVVSPAAQAVCDLFGMNPYAAISEGTLIITCRPEKAGAVLTRLEDA 310

Query: 295 PLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
             G  A  +GE+   +        G +  L+ P  +P  
Sbjct: 311 --GIAATQVGEITPPEEGIRLVRDGREEPLEHPRVDPFW 347


>UniRef50_C0CMS4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C0CMS4_9FIRM
          Length = 339

 Score =  220 bits (561), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 76/334 (22%), Positives = 129/334 (38%), Gaps = 21/334 (6%)

Query: 12  GQAMQQ-LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+  +Q L+ S+  +                D A L    D +         DP+     
Sbjct: 4   GKLPEQVLVRSVIKKISHRRDEVLFGPGVGRDCAALKLAKDEIFV----ISSDPITGTVK 59

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IG   I  TAND+A +GA P  +    +L      + L+ +V  M +T  A  + ++ G
Sbjct: 60  DIGSHCIYITANDLAAAGAEPVAVMVTALLPPETEEKDLRGIVEDMEKTCAALDMEVIGG 119

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T+V     V +  ++  G+G + A      + L AG  L+V+  +G  G +I+      
Sbjct: 120 HTEVTD--TVKQPLLSVTGVGKMKAGEALYEKKLKAGQDLVVTKWIGLEGTSIVAKERAQ 177

Query: 191 G----LDGELVSDCAVLTPLIQTLRDI-----PGVKALRDATRGGVNAVVHEFAAACGCG 241
                     V         +  L +       GV  + D T GGV   + E A     G
Sbjct: 178 KLREVFAESFVRTAQNFDQYLSVLPESRIAMEHGVSVMHDITEGGVFGALWELAQGADVG 237

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           +++    +P++     VCE  GL+     + G ++I       E ++  L     G    
Sbjct: 238 LDVDLKKIPIRQETVEVCEQFGLNPYLLMSSGAMLIGT--EQGEILVRKLQEA--GIPGT 293

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           +IG+ VE     L     + R LD P ++ L +I
Sbjct: 294 VIGQAVEGSSRILRNGEEI-RYLDRPQSDELYKI 326


>UniRef50_B8D020 AIR synthase related protein domain protein n=1 Tax=Halothermothrix
           orenii H 168 RepID=B8D020_HALOH
          Length = 348

 Score =  218 bits (557), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 66/306 (21%), Positives = 117/306 (38%), Gaps = 22/306 (7%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
               D A +    + L  S+D     P+       G LA+    ND+A  GA P  +   
Sbjct: 31  GIGEDSAVVDFGDEVLVISSD-----PITGAVNKAGYLAVHVACNDLASCGARPVGIQVV 85

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
            +L        +  ++  +   A +  + ++ G T+++ +  V +  I    +G  P + 
Sbjct: 86  LLLPPATEEIMVGNIMEEITRAAASIEVEVIGGHTEILSK--VTEPIITVTAIGKAPRDK 143

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILN-----LREQLGLDGELVSDCAVLTPLIQTLRD 212
           +        GD L+++  LG  G  IL      L +  G+  E++         +  L +
Sbjct: 144 YITTGGARPGDELIITKGLGIEGTFILASDYAELLKDRGVPPEIIERGQEYISKLSVLEE 203

Query: 213 -----IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDAL 267
                  GV A+ D T GG+   + E   A   G  +  +  PV P    +C+ L LD  
Sbjct: 204 GLIGAGLGVHAMHDITEGGLYGALDEMVTASKAGFRIKRSQFPVNPETDIICKALDLDPA 263

Query: 268 NFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLP 327
              + G ++IA       +++  L     G  A++IGE+ E  G  +    G    L   
Sbjct: 264 GLISSGSMLIAAP--DGGKLVDKLARA--GIKASIIGEITEE-GCLIEDENGEFEELSGE 318

Query: 328 HAEPLP 333
             + L 
Sbjct: 319 IKDELW 324


>UniRef50_B5Y6B6 Hydrogenase expression/formation protein HypE n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y6B6_COPPD
          Length = 339

 Score =  216 bits (551), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 66/289 (22%), Positives = 111/289 (38%), Gaps = 18/289 (6%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
            A  +   +   GD L  S     +DP+      IG LA+    ND+A SG  PR++   
Sbjct: 30  SAFGEDVAVTRVGDDLLLSH----VDPIVGAVNGIGWLAVHVACNDIAASGIKPRWVQLL 85

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
            +L      E LK +++  A  A +  + I+ G T+      + +  +    +       
Sbjct: 86  VMLPSLDQPEELKQIMSDAARAADSLNVTIIGGHTEA--SNGLRRPLVAATALAPACGKR 143

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILN-----LREQLGLDGELVSDCAVLTPLIQTLRD 212
                    GD++ V+  +G  G  IL         + GL  + +++   L   +  + +
Sbjct: 144 VVRTSGAKPGDIIYVTRGVGLEGTGILASDFAVEARKRGLTDQDLNEALKLLSSVSVVSE 203

Query: 213 I-----PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDAL 267
                  G  A+ D TRGG+   + E A+  G  +E+  + +PV   V+        D L
Sbjct: 204 ALKLADLGATAMHDVTRGGILETLLEIASCSGVCMEVDRSRIPVPEVVKRFANAFEFDPL 263

Query: 268 NFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAG 316
              + G LV  +     E   A   + P       IG V E +GV L  
Sbjct: 264 KMISSGTLVATLPPEMCETAEALFENQP--CKLFRIGVVTEGRGVLLRS 310


>UniRef50_A8MDD6 AIR synthase related protein domain protein n=1 Tax=Caldivirga
           maquilingensis IC-167 RepID=A8MDD6_CALMQ
          Length = 337

 Score =  214 bits (546), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 71/317 (22%), Positives = 122/317 (38%), Gaps = 21/317 (6%)

Query: 13  QAMQQLINSLFMEAFA-NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           +     I     +                 D A +      +A  TD     P+      
Sbjct: 3   KFSNAFIEREVFKMLGVRDNSVTLGPGIGEDAAVIRINNSYMAVHTD-----PVTGSSNL 57

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G LA+   AND+A  G  PR+     IL        +  ++  + +       ++V G 
Sbjct: 58  LGWLAVHVAANDIATRGIRPRWFLVTLILPVDYGENDVVNIMRQINDALIEINASLVGGH 117

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL--NLREQ 189
           T+  +  AV +    T  +G     I  G   L  GDV++++         +L  + R +
Sbjct: 118 TE--KSDAVTRPIAVTTAIGIGSRFIRTG--GLRTGDVIVMTKYAALEATAVLVSDFRGR 173

Query: 190 LG--LDGELVSDCAVLTPLIQTLRDIPGV----KALRDATRGGVNAVVHEFAAACGCGIE 243
           L   L      +   L  ++  + D         ++ D T GGV   + E A + G  I 
Sbjct: 174 LMNVLSEGEFKEATSLYRMVSVVNDALAAAEYATSMHDPTEGGVLQGLLEMAYSSGKLII 233

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           ++E  +PV P  R V     L+ L   + G L+I V  N A +++  L    +G +A++I
Sbjct: 234 INEDNIPVLPVTRRVLNAFNLNPLTVLSSGSLLIGVGENDAAKLIGKLRD--MGINASII 291

Query: 304 GEVVER-KGVRLAGLYG 319
           G+V +   GV + G  G
Sbjct: 292 GKVTDGEPGVVVKGRSG 308


>UniRef50_A4WH94 AIR synthase related protein domain protein n=5
           Tax=Thermoproteaceae RepID=A4WH94_PYRAR
          Length = 335

 Score =  213 bits (544), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 78/287 (27%), Positives = 112/287 (39%), Gaps = 20/287 (6%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
               D A +   G  L   TD     P+      +G LA+    NDVAV G  P +LS  
Sbjct: 31  AIGEDAAVVDLGGKYLVAHTD-----PITGSVNLLGSLAVYVPTNDVAVRGVEPMWLSVA 85

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
            +L  G   + L A+   M   AR  G+ IV G T+V    AV +       MG    + 
Sbjct: 86  LLLPPGASDDLLDAITRQMDMAARRLGVTIVGGHTEVTT--AVTRPVAVVTAMGV--GSR 141

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILN---LREQL--GLDGELVSDCAVLTPLIQTLRD 212
                    GDV++++ + G   A+IL      E L  G+  E +     L   I   R+
Sbjct: 142 FVSTSGAKPGDVVVMTKSAGQETASILASDFAEEALRRGVPAEALERARGLIAEISVARE 201

Query: 213 IPG----VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALN 268
                    ++ D T GGV   + E A A    I++    + V   V  +C    +D L 
Sbjct: 202 ALALADLATSMHDPTEGGVANGLAEIAYASKVSIDVRRKDVVVYREVEALCRAFRIDPLE 261

Query: 269 FANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLA 315
             + G L+  V R    + L  L    LG   A+IGEV    G  + 
Sbjct: 262 TLSSGVLLATVPRGRLGEALERLQK--LGVPHAVIGEVKPPSGYLVK 306


>UniRef50_A3DLS7 AIR synthase related protein domain protein n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DLS7_STAMF
          Length = 355

 Score =  212 bits (541), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 63/337 (18%), Positives = 128/337 (37%), Gaps = 25/337 (7%)

Query: 11  GGQAMQQLINSL--FMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP 68
           GG+   + ++ +   +       +         D A +  +   L   +D     P+   
Sbjct: 23  GGKPSWEFLSEMLSILPTMDPDLIVGP--SIGEDAAIIRFKDGFLIVHSD-----PITAA 75

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
              IG LA+   AND+AV GA PR+     +L    P+E ++++   +    R+ G  ++
Sbjct: 76  TRRIGWLAVHIVANDIAVRGATPRWFLPVILLPPKYPVEQIESIFEDIGLATRSLGATVI 135

Query: 129 TGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
            G T+      + +  I+   +G     +    +    GD + + G +G  GA+++    
Sbjct: 136 GGHTEFTP--GIPRPIISMTAIGYSMDKVVL-TRNARPGDKIFIIGRVGGEGASVIAWDF 192

Query: 189 Q-----LGLDGELVSDCAVLTPLIQTLRDI----PGVKALRDATRGGVNAVVHEFAAACG 239
           +      G+  ++++        I  +         V ++ D T GG+   + E A A  
Sbjct: 193 EDLLLRKGISRDIIAKAKEYFTGISVVDKALLIRDYVNSMHDPTEGGLLQGLREVAKASN 252

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I L    + + P V+ +   L LD L   + G L+ +V +    QV   L        
Sbjct: 253 TRIILDADKIILDPVVKEITSALKLDPLKILSSGVLIASVPKENTRQVEDLLQEKEY--K 310

Query: 300 AALIGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPR 334
            ++ G + E  + G  +    G    +     + + +
Sbjct: 311 YSIAGYISEYVKGGELIVEQNGKTIRIIEDVVDEIYK 347


>UniRef50_B6YUV4 HypE n=3 Tax=Thermococcus RepID=B6YUV4_THEON
          Length = 332

 Score =  211 bits (537), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 75/330 (22%), Positives = 124/330 (37%), Gaps = 21/330 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQ-EDQARLDLAQLVAEGD-RLAFSTDSYVIDPLFFPG 69
           G+    ++  +         +      +   D A L  + +  L  +TD      L  P 
Sbjct: 6   GKLRNDVLREVVFPNIGIEDVRVIYGPREGFDSAVLEYDHEHYLIVATDPT----LGVPE 61

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
              G       A+DVAV GA PR+L    +   G     L+ ++ S+    R  G +I+ 
Sbjct: 62  ETFGFFTYHFAASDVAVFGARPRWLIVDLLFPPGTERSFLENIMRSLNTECRKYGSSIIG 121

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH-GATILNLRE 188
           G T       + +    T  MG +  +          GD ++V+  +G     +    RE
Sbjct: 122 GHTGAYP--TIAEPTSTTTAMGLVRKDELKLP-LAEPGDKIIVTAKIGLEFAVSAAYFRE 178

Query: 189 QLGLDGELVSDCAVL-------TPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
           +         +   L       T L   L   P V+ + DAT GG+   +HE A   G G
Sbjct: 179 EELRKFLTFKEIERLKRLFTFETALPDALIARPFVRGMHDATEGGL-TALHEIAENSGVG 237

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             +    L + P VR V E  GL+  + ++ G L+       A+ ++  L+ +  G  A 
Sbjct: 238 FRVYADRLYLDPLVRKVLEFYGLEPWSVSSTGTLIAITPPEKADALITELNKN--GIMAF 295

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEP 331
            +GE  E K   L    G ++T      +P
Sbjct: 296 ELGEFTEEKERVLV-KGGKEKTFPTFERDP 324


>UniRef50_B0R9W2 Hydrogenase expression/formation protein n=3 Tax=Halobacteriaceae
           RepID=B0R9W2_HALS3
          Length = 340

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 87/313 (27%), Positives = 129/313 (41%), Gaps = 20/313 (6%)

Query: 19  INSLFMEAFANPWLAEQEDQA------RLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI 72
           I++ F     +P L   +D         +D   L   G RL  S D   ++P        
Sbjct: 8   IDAEFFAQHLSPNLGADDDAVTVGPQYGVDFGVLSIGGQRLVVSADPVSVNP-GVGIERA 66

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+LA+    +DVAVSG  P +LS   +L      +T+ A+  +MA      G+++VTG T
Sbjct: 67  GRLALHSVLSDVAVSGVPPSFLSITLVLPASARDDTIAALWDAMATECERLGVSVVTGHT 126

Query: 133 KVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR--EQ 189
               R  V   +I     MG             TAGD +L++ + G   A +      + 
Sbjct: 127 A---RQDVSFPWIGGATAMGVGDPAEIVRPDGATAGDTVLMTHSPGAEVAGLFAALFGDH 183

Query: 190 LGLDGELVSDCAVLTPLIQTLRDIPG-----VKALRDATRGGVNAVVHEFAAACGCGIEL 244
           L +  + V            + D        V A+ DAT  G+   + E A A G  I +
Sbjct: 184 LDVADDTVERADARLEDTTVVGDACAAASAPVTAMHDATECGIQGALVELATAAGVSISV 243

Query: 245 SEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           S  A+PV   V  VC  LGLD    ++ G L++ V    A+  +AAL +       A IG
Sbjct: 244 SSDAVPVPEDVSAVCADLGLDPWQVSSRGTLLVTVPEAHADTAMAALDARN--TPVAAIG 301

Query: 305 EVVERKGVRLAGL 317
            V E  GV + G 
Sbjct: 302 TVSEGSGVTVDGT 314


>UniRef50_C7H113 Hydrogenase maturation factor n=1 Tax=Eubacterium saphenum ATCC
           49989 RepID=C7H113_9FIRM
          Length = 347

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 66/315 (20%), Positives = 122/315 (38%), Gaps = 20/315 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQA-RLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+    ++  +             +      D A +         STD     P+     
Sbjct: 13  GKLDSDILEKIVFGNIRYKSADVIKRAGLGEDCAVMDFGEYDCIVSTD-----PITATPN 67

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            IGKLA+  + ND+A +G  P  L+   +L +G   E ++ ++    E A    + IV G
Sbjct: 68  EIGKLAVYISCNDIASNGIEPFALTMSVLLPKGTTEEEVELIMKQAGEAAMDLEVEIVGG 127

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ- 189
            T++    AV +  I +   G            ++ GD++ V+  L   G  I+    + 
Sbjct: 128 HTEITT--AVVRPVIVSTVFGKSLRGESQTCDLMSEGDLICVTKDLALEGTAIIVGDHED 185

Query: 190 ---LGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACGCG 241
                L  + +         I  ++D       G   + D T GG+   V E       G
Sbjct: 186 IMSKVLSEDEIKQAKSFMDSISVVKDGVLAGSIGTHGMHDVTEGGILGAVWEMCMNSKLG 245

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             + E  +P+    + V + L +D L   + G +V+A+ ++    +  A     +G   +
Sbjct: 246 AVIYEDEIPLNDITKKVMKYLDVDPLKMISSGSMVMAISKDKKRAMEEAFKDAGIG--FS 303

Query: 302 LIGEVV-ERKGVRLA 315
           +IGE+V E++G+ L 
Sbjct: 304 VIGEIVDEKEGIVLK 318


>UniRef50_C6A3P3 Hydrogenase expression/formation protein HypE n=2 Tax=Thermococcus
           RepID=C6A3P3_THESM
          Length = 349

 Score =  207 bits (528), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 74/329 (22%), Positives = 134/329 (40%), Gaps = 21/329 (6%)

Query: 12  GQAMQQLINSLFMEAFA-NPWLAEQEDQARLDLAQLVAEG-DRLAFSTDSYVIDPLFFPG 69
           G+   +++N++ ++  + N        +   D A L  +  + L  +TD      L  P 
Sbjct: 26  GKIRSEVLNNIILKNISVNDPKIVFGPKEGFDAAVLEYDEKNYLVIATDPI----LGVPK 81

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            + G       ++DVAV GAIP++L    +L  G   E L +V+  + E  +  G +I+ 
Sbjct: 82  EHFGFFTYHFASSDVAVFGAIPKWLIVNLLLPNGTTEEDLNSVMRELNEECKKYGTSIIG 141

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH---GATILNL 186
           G T V            T  +G +  +          GD ++++  +      GA     
Sbjct: 142 GHTGVYSTTRSFTAT--TTAIGLVKKDELKLP-LAKPGDDIIITKGIAIEFAVGAAWFRT 198

Query: 187 RE-QLGLDGELVSDCAVLTPLIQTLRDI----PGVKALRDATRGGVNAVVHEFAAACGCG 241
            E +  L    +S    +  L   ++D        + + D T GG+   +HE A     G
Sbjct: 199 EELKKILSPSQISSLREMYTLETVVKDALLAKKFARGMHDVTEGGL-TTLHEIADNSEVG 257

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
            E+    L + P V+ V +  G++ L  ++ G L+I   +    +++ ALHSH  G +A+
Sbjct: 258 FEVYYEKLHMPPLVKKVVKFYGVNPLTVSSTGTLIIISPQENTSKLIKALHSH--GINAS 315

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAE 330
            +G+  E K   L    G K        +
Sbjct: 316 TVGKFTEEKERALIKK-GRKEEFPKFEKD 343


>UniRef50_Q6KZH8 AIR Synthase n=1 Tax=Picrophilus torridus RepID=Q6KZH8_PICTO
          Length = 334

 Score =  207 bits (528), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 74/338 (21%), Positives = 143/338 (42%), Gaps = 32/338 (9%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQARL------DLAQLVAEGDRLAFSTDSYVIDPLFFP 68
           M   I+  F E+     L    D+  +      D+  +      LA +TD + IDP+F  
Sbjct: 1   MTGKISREFFESNIIKRLGFLRDEVVVPPENGVDVGIVRLGNGYLAVTTDPFYIDPVFG- 59

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
                        +D+  SG    Y+S    L + +  +    + T + + ++   + +V
Sbjct: 60  LKKAAWFGFHILLSDIYTSGIPAMYMSIDLNLPQSMSDDEFNEIWTVINDESKKYNVMVV 119

Query: 129 TGDTKVVQRGAVDKLFIN-TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN-- 185
           TG T   +   V    I     MG    + +   +    GD+++++ T     + IL+  
Sbjct: 120 TGHTA--RYAGVSYPMIGGVTLMGY--GDRYITTKNAGDGDIIIMTKTCALEASCILSYT 175

Query: 186 ----LREQLGLDG-----ELVSDCAVLTPLIQTLR-DIPGVKALRDATRGGVNAVVHEFA 235
               + + LG+D      +L      +   I ++   +  + ++ DAT GG+   ++E  
Sbjct: 176 FPEYIEKHLGMDTLKKLNDLFYKMTCVNEEILSIDFGLDKITSMHDATEGGIINALYEIG 235

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
            A G G+ +++  + +  +V  V +L  +D L   +EG L+I V+RN A+++L  L S  
Sbjct: 236 KASGHGVIVNKNNINIDESVSRVTKLFNIDPLRSISEGTLLITVKRNFADELLLKLRSA- 294

Query: 296 LGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
            G D+ +IGE+   KG  +    G    +  P  + + 
Sbjct: 295 -GIDSYIIGEL---KGDEIKFDTG---EMIKPGDDQIW 325


>UniRef50_UPI0001B4B0DD hydrogenase expression/formation protein HypE n=1 Tax=Streptomyces
           sp. C RepID=UPI0001B4B0DD
          Length = 339

 Score =  207 bits (527), Expect = 5e-52,   Method: Composition-based stats.
 Identities = 102/287 (35%), Positives = 159/287 (55%), Gaps = 9/287 (3%)

Query: 54  AFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVV 113
           A  + ++V+DP F+  G+IG++A+C T N++A +GA P  L+   ++E GLP+E L  + 
Sbjct: 54  ALVSGAHVVDPPFYGSGDIGRIAVCATVNELAAAGARPLALTLSAVVEAGLPLERLHRLA 113

Query: 114 TSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVS 173
            S+ + AR A + +   D +VV+ G  D+++++T G+GA         +    GD +L+S
Sbjct: 114 RSVRDAAREADVVVAGVDVRVVRAGEADQVYLHTTGIGAF-HGAPLDTRDARPGDRVLLS 172

Query: 174 GTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP---GVKALRDATRGGVNAV 230
             LG HGA IL++R  LG +  + S CA L  L++  R      G++A+R  TRGG+ A 
Sbjct: 173 APLGGHGAHILSVRRGLGFESLVPSGCAPLAGLLERARAAASGDGIRAVRTVTRGGLAAA 232

Query: 231 VHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAA 290
           +H +A   G  + + E+ALPV+   R   E + +D L+ ++E  L + V  +AA  VLAA
Sbjct: 233 LHAYARELGHTLRVEESALPVQYEARMALEAMAVDPLHASSESCLCLLVAPDAAPGVLAA 292

Query: 291 LHSHPLGKDAALIGEVVERKGV---RLAGLYGVKRTLDLPHAEPLPR 334
           L +HP G+ AA IG VVE        L    G       P A   PR
Sbjct: 293 LRTHPYGRFAAEIGTVVEDGAAPVELLRDRGGAVPVTPEPAA--FPR 337


>UniRef50_D2RZQ8 AIR synthase related protein domain protein n=1 Tax=Haloterrigena
           turkmenica DSM 5511 RepID=D2RZQ8_9EURY
          Length = 346

 Score =  205 bits (523), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 83/334 (24%), Positives = 128/334 (38%), Gaps = 23/334 (6%)

Query: 19  INSLFMEAFANPWLAEQED------QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI 72
           I+  F +    P L    D      Q  +D   L   G  L  +TD   I P        
Sbjct: 7   IDRQFFDRHVAPNLGADRDDVAVGPQHGVDFGVLEIGGQALVTATDPVSIMPQLG-LERA 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
            + A+     DVAVSG  P +LS  F L E +  +    V  ++ E     G+A+VTG T
Sbjct: 66  ARFALDLVLADVAVSGIPPSHLSICFTLPETMTDDEFATVWKTIHEECVDLGVAVVTGHT 125

Query: 133 KVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL----R 187
                 +    ++     M     +          GD LL++         +L+     +
Sbjct: 126 ARYSDPS--HPWVGAATAMAVGDPDEIVRPDGARPGDRLLLTTGPAVESVGLLSTLFADQ 183

Query: 188 EQLGLDGELVSDCAVLTPLIQTLRDIPG------VKALRDATRGGVNAVVHEFAAACGCG 241
            +  L G+++ D       +  +RD         V A+ D T GG+   ++E A   G  
Sbjct: 184 LEAALPGDVIDDAQDRLEEVYCVRDALAAAAAGPVTAMHDVTEGGLAGALNEMADGAGAR 243

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             +   A+P++P V+ VC+ L +D     + G L++AV     + V+AAL         A
Sbjct: 244 FSVDRDAVPMRPGVQEVCDHLEIDPWAATSSGSLLLAVAPEGVDDVVAALEDRD--TVVA 301

Query: 302 LIGEVVERKGVRLAGLYGV-KRTLDLPHAEPLPR 334
            IG V E  G    G   V    L  P  +P  R
Sbjct: 302 EIGRVEEPSGTDGDGEVVVDGDRLPHPSVDPSWR 335


>UniRef50_Q9YA95 Putative hydrogenase expression/formation protein HypE n=1
           Tax=Aeropyrum pernix RepID=Q9YA95_AERPE
          Length = 345

 Score =  205 bits (522), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 78/309 (25%), Positives = 120/309 (38%), Gaps = 25/309 (8%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
               D A +      L        +DP+   G   G LA+   AND+AV+GA PR+    
Sbjct: 37  SVGEDAAIVSLGPIDLVMH-----LDPITEAGALAGWLAVHVAANDIAVTGARPRWEMLA 91

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
            ++  G   ++L +++      A   G+ IV G T+      V +  I  A  G      
Sbjct: 92  VLMPPGSSEDSLASLLGDAVRAAEEIGVEIVGGHTEAAP--GVPRPIIVAAAAGITCGGC 149

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILNL------------REQLGLDGELVSDCAVLTP 205
                    GD++L        G  I+               + +     L S  +++  
Sbjct: 150 TTPTSAARPGDLVLQVKPAAIEGTAIIATDFADMLRSRGVGEDAIAGARMLASRVSIVEE 209

Query: 206 LIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD 265
            I+ L +   V+A+ D T GGV   + E A A    IE+ E  + V  A R V   LG+D
Sbjct: 210 AIE-LAEAGVVRAMHDPTEGGVLGGLVEMALASRTVIEVEEDKIIVGEATRIVASALGID 268

Query: 266 ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG---VRLAGLYGVKR 322
            L   + G L+  V  + A +    L    LG + + IG V  R G   +RL+    VK 
Sbjct: 269 PLRLISSGTLLATVPPDKAGEARYVLEE--LGVEYSFIGRVAARSGEPALRLSSRGRVKT 326

Query: 323 TLDLPHAEP 331
             + P  E 
Sbjct: 327 FREPPMDEI 335


>UniRef50_B1CC54 Putative uncharacterized protein n=1 Tax=Anaerofustis
           stercorihominis DSM 17244 RepID=B1CC54_9FIRM
          Length = 324

 Score =  199 bits (506), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 63/336 (18%), Positives = 126/336 (37%), Gaps = 29/336 (8%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARL-DLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+   + +  +            +       D A L  + D    STD     P+     
Sbjct: 4   GKLSNETLEKILFNKIKIKNKEVKIGAGIGKDTAMLDFQNDLFIISTD-----PITGSKN 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            IGKL +  + ND+A + A P  +    ++     ++ ++ ++  +  T     + ++ G
Sbjct: 59  GIGKLCVNISCNDIATAMARPVAIMITMLIPTYAKIKDVEEIIDDILLTCDENNVDLIGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL---- 186
            T+V    +V+K  ++   +G       +      AGD +++S   G  G+ I  L    
Sbjct: 119 HTEVTS--SVNKFILSGVCIGRKEKRKEFLPS---AGDKVVMSKYAGLEGSAIAALDLEE 173

Query: 187 -------REQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
                  +E+     EL++   V+   +  +     V  L DAT GG+   V E A    
Sbjct: 174 EVKNILTKEEFEKTRELINHTNVIKEGL--IARNHEVSLLHDATEGGIFGGVWEMATNSN 231

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            G  ++   + +    + + E  G+D     + G ++   + +   +++  L        
Sbjct: 232 LGAVINTDDILILDETKKIAEHFGIDPYKLISSGVMLFITKNDK--ELIEDLKKEN--IP 287

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           A+ IG + E K +        K  L  P  + L +I
Sbjct: 288 ASTIGYLTEEKEIYTI-KNNKKEILSPPEQDELYKI 322


>UniRef50_Q6AQZ8 Related to hydrogenase expression/formation protein (HypE) n=1
           Tax=Desulfotalea psychrophila RepID=Q6AQZ8_DESPS
          Length = 345

 Score =  198 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 71/306 (23%), Positives = 125/306 (40%), Gaps = 17/306 (5%)

Query: 40  RLDLAQL-VAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGF 98
            LD A L  A+G  +A + D     P   P   +G   +   A+D+AV+G  P +++   
Sbjct: 37  GLDAAILQTADGRVMAIAEDPIFPAP-GLPLDIMGWFTVHIGASDIAVTGVKPEFMTYTL 95

Query: 99  ILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI-NTAGMGAIPANI 157
           +L  G P E  + +++S++  A   GI+IV G T     GAV    +      G    + 
Sbjct: 96  LLPLGCPEEDARTIISSISRAAEDLGISIVGGHTG--WYGAVTVPTVGGVTVWGTADQDA 153

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILNL----REQLGLDGELVSDCAVLTPLIQTLRDI 213
                    GD++L++       A +L++    R Q  +  E+++        I  + D 
Sbjct: 154 WISPGGAKDGDLILMTKGPCIEAAALLSIVHHERLQGNISEEMLATLRARVDQITVVEDA 213

Query: 214 ------PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDAL 267
                  GV A+ DAT GGV   + E + + G  + +    + +   +  +   L  D  
Sbjct: 214 LHAFKVGGVHAMHDATEGGVQGGLWEMSTSSGLPVMVDFDGVEIPADIVALARELDFDPW 273

Query: 268 NFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLP 327
              +EG L+ AVE    ++V        LG D+ ++G+             G  + L  P
Sbjct: 274 QAISEGTLLAAVEPEQVQEVQRVW--ADLGIDSYILGKFDSSLKENTVLKNGQSQPLLEP 331

Query: 328 HAEPLP 333
            ++P  
Sbjct: 332 DSDPFW 337


>UniRef50_Q5ZXK3 Thiamine monophosphate kinase (AIR synthase) n=6 Tax=Legionella
           RepID=Q5ZXK3_LEGPH
          Length = 325

 Score =  198 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 78/328 (23%), Positives = 120/328 (36%), Gaps = 31/328 (9%)

Query: 18  LINSLFME---AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN--- 71
           LI+  F        +      +D A L     V +G  L  STD+ V    F P  +   
Sbjct: 13  LIDHYFKSIPCKRNDVLFGIGDDAACLQ----VPDGMHLLVSTDTLVSGIHFLPQWDPYD 68

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           I   A+    +D+A  GA P +++    L E L    L +    + ++     + ++ GD
Sbjct: 69  IACKAVMVNISDMAAMGAQPCWVTLALTLPE-LNQSWLDSFARGIKDSLGLYNVDLIGGD 127

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T          L I    MG  P           AGD ++VSG LG  G  +  L E   
Sbjct: 128 TTKGP------LSITLTIMGLTPQGQAIRRCGAQAGDAIMVSGELGAAGLAVKLLDEHKK 181

Query: 192 LDG----ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           ++     EL++      P +     +            G+ A ++   AA G G  L E 
Sbjct: 182 VNAKDKVELMNKLLHPKPRVDLCHLLRKYATSAIDISDGLGADLNHICAASGVGANLFEE 241

Query: 248 ALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           A+P  P +   C    LD AL+  ++ +L   V     +     L    L      IG +
Sbjct: 242 AIPRHPLLNQYCPEQALDLALSGGDDYELCFTVSIQQLDSFNRDLQKENLI--CFPIGVI 299

Query: 307 VERKGVRLAGLYGVKRTLDLPHAEPLPR 334
            E+ G+R+          D P  E  PR
Sbjct: 300 EEKPGLRIQSA-------DSPSKELQPR 320


>UniRef50_C1TRR7 Hydrogenase maturation factor n=1 Tax=Dethiosulfovibrio
           peptidovorans DSM 11002 RepID=C1TRR7_9BACT
          Length = 343

 Score =  197 bits (502), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 62/288 (21%), Positives = 105/288 (36%), Gaps = 19/288 (6%)

Query: 42  DLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILE 101
           +   LV  G  L  S     +DP+      +G+LA+    ND+A  G  PR+     ++ 
Sbjct: 34  EDVALVDTGSGLVASH----VDPIVGASEGLGRLAVHVACNDIAAGGIRPRWAQLLVLVP 89

Query: 102 EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGA 161
           +    + LK ++    + A+   + IV G +      A+ +        G+         
Sbjct: 90  DKGDEDILKDIMEDAVKAAQEISVTIVGGHSGYTS--ALSRPLAAVTAFGSAEPGQMVST 147

Query: 162 QTLTAGDVLLVSGTLGDHGATILNLR-----EQLGLDGELVSDCAVLTPLIQTLRDI--- 213
              + GD++ V+  +G  G  IL            L    +++   L   +  + +    
Sbjct: 148 GGASEGDIVCVTRGVGLEGTAILAWDYPEECRSKELPEGDIAEARSLADKLSVVEEALKL 207

Query: 214 --PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFAN 271
              G  A+ D TRGGV   + E A   G    +   ALP+   V         D +   +
Sbjct: 208 ASLGATAMHDPTRGGVLEAMCEMAQGAGMSFRIDGDALPISETVDRFSRAFDFDPMRMIS 267

Query: 272 EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYG 319
            G LV+ +   A E+  A L S         +G V    GV +    G
Sbjct: 268 SGALVVTLPGEAVERAGAELGS---IAPLYPVGVVERGTGVTITSSSG 312


>UniRef50_UPI000038DF5E AIR synthase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI000038DF5E
          Length = 343

 Score =  194 bits (494), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 68/335 (20%), Positives = 124/335 (37%), Gaps = 28/335 (8%)

Query: 19  INSLFMEAFANPWLAEQEDQARL------DLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI 72
           I+  F E      +    D+  +      D+  +      +A +TD   ID   F     
Sbjct: 5   ISRKFFEENIINKIGTLRDEVVVPPKNGVDVGIVKIGDKYMAVTTDPLYIDK-SFGFKKA 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
              A     +D+  SG    Y+S    L   +     K +   + E      I +VTG T
Sbjct: 64  AWFAFHILLSDLYTSGIPASYMSIDLNLPSSITDNEFKEIWDVINEECIKYNIEVVTGHT 123

Query: 133 KVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN------ 185
              +   V+   +     MG          +    GD ++++ +     A IL+      
Sbjct: 124 A--RYNGVEFPMVGGITLMGT--GEKFITTENAGVGDRIIMTKSCALETALILSNTFPEY 179

Query: 186 LREQLGLDG--ELVSDCAVLT-----PLIQTLRDIPGVKALRDATRGGVNAVVHEFAAAC 238
           +R  +G +    ++     +T      L         + ++ DAT GG+   ++E   A 
Sbjct: 180 VRNNIGEENYKSIIGKFYTMTCVGEETLAIEYGISERITSMHDATEGGLLNAIYEIGIAS 239

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
           G G+ +    + +   +  +C L  +D L   +EG L+I V+   A + L  L S   G 
Sbjct: 240 GNGLSVDYNKIIIDSDIEKLCNLFNIDPLRSISEGTLLITVKEQYAMEFLTILQSS--GI 297

Query: 299 DAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
           +A+LIGE+++          G +  +  P  + L 
Sbjct: 298 EASLIGEILDNSKGIKILKDGKQEDI-RPEDDQLW 331


>UniRef50_B8D6Q8 AIR synthase related protein domain protein n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D6Q8_DESK1
          Length = 331

 Score =  193 bits (490), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 61/293 (20%), Positives = 116/293 (39%), Gaps = 21/293 (7%)

Query: 42  DLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILE 101
           D A +  +   L        +DP+       G LA+   +ND+AV G  P++     ++ 
Sbjct: 35  DAAVIRFKDGFLVTH-----VDPITTGVKKAGYLAVHVASNDIAVRGVTPKWFMPVVLIP 89

Query: 102 EGLPMETLKAVVTSMAETARAA-GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWG 160
               +E  + + + M +      G+AI  G T+V     +D+  I    +G         
Sbjct: 90  RHYSVEEAEELFSDMGKALSEIHGVAI-GGHTEVTP--GLDRPIIAMTVIGYTN-GRVIS 145

Query: 161 AQTLTAGDVLLVSGTLGDHGATILNLREQLGL----DGELVSDCAVLTPLIQTLRDIPGV 216
            +    GD ++V G +G  GA ++       L      +++         +  ++    +
Sbjct: 146 TRDAGEGDYVVVIGRIGGEGAGVIAWDFGDKLLGKVPRDVIEHARSFIYDVSIVKTALAI 205

Query: 217 K----ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANE 272
           K     + DAT GG+   + E A+A    I + + A  +   V+ +   + +D L   + 
Sbjct: 206 KDYVNTMHDATEGGILQALREVASASKKDIVVLDKAFYIDEEVKRITSAVNVDPLRLLSS 265

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG-VRLAGLYGVKRTL 324
           G +V  V     + +L  L  H  G   +++G V   +G V + G  G   T+
Sbjct: 266 GCIVATVAPGYLDSLLNELKKH--GIRHSVVGRVTRGEGRVIIKGDSGETITI 316


>UniRef50_C9RAP1 Thiamine-monophosphate kinase n=1 Tax=Ammonifex degensii KC4
           RepID=C9RAP1_AMMDK
          Length = 339

 Score =  192 bits (488), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 76/312 (24%), Positives = 118/312 (37%), Gaps = 24/312 (7%)

Query: 30  PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVA 85
           P   E       D A L        F+TD  V    F        ++G   +    +D+A
Sbjct: 20  PSAREVIQGVGDDAAVLAVGDKWFLFTTDVLVEKVHFRWDLASPADVGFKTLAVNVSDIA 79

Query: 86  VSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI 145
             G  P Y      L    P+E ++     + E A    + +V GD         D  F 
Sbjct: 80  AMGGRPTYALVTLGLPLDFPVEKVEEFYAGLKEAAEEYEVILVGGD-----ITRSDIFFA 134

Query: 146 NTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVS------- 198
             A +G +        +    GD+L V+G LG   A ++ L  +  L  E ++       
Sbjct: 135 GVALLGEVEPGKAKFRKGARPGDILCVTGPLGGAAAGLVLLESKEELLPETMAHFLRRKY 194

Query: 199 -DCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRG 257
                     + L D   V AL D +  G+    H  A A G  + L  AALP+ P  + 
Sbjct: 195 RRPDARLEAGRILGDFEEVHALIDISD-GLAGDAHHLARASGVEVNLYRAALPIYPPAQE 253

Query: 258 VCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           +   LG+D     L    + +L+  VE +A  +V  AL    +G +   +G V E +GV+
Sbjct: 254 LGRRLGIDPARWALFGGEDYELLFTVEPSAVGKVAKALEG--VGLNLFPLGFVEEGEGVK 311

Query: 314 LAGLYGVKRTLD 325
           L    G +  L+
Sbjct: 312 LVLPDGREEELE 323


>UniRef50_A1HSU1 Thiamine-monophosphate kinase n=1 Tax=Thermosinus carboxydivorans
           Nor1 RepID=A1HSU1_9FIRM
          Length = 346

 Score =  191 bits (486), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 83/321 (25%), Positives = 131/321 (40%), Gaps = 19/321 (5%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG-----NI 72
           LI+ +  +A   P           D A L+    +L   T   +++ + F  G      +
Sbjct: 26  LIDLIQTDAIQEP--GTVVVGIGDDAAVLLPTPRQLQLLTADMLVEGVHFDLGRTTAWQL 83

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  AI    +D+A  G +PR+      L   +P+E +  +   M E  R   + IV GDT
Sbjct: 84  GYKAIAVNLSDIAAMGGVPRHAVISLALPRQIPVEFVVNLYQGMKEICREFRVNIVGGDT 143

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT--ILNLREQL 190
                G    L IN A MG +             GD++ V+G LG   A   +L+L    
Sbjct: 144 VASPHG----LIINVAVMGEVEPTQLVRRSGAQVGDMVAVTGVLGSSAAGLDLLSLDNWA 199

Query: 191 GLDGELVSDCAVLTPLIQT----LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
             D       A LTP  Q     L  + G  ++ D +  G+ +  HE A A   G+ +  
Sbjct: 200 EYDFAWPLVTAHLTPRPQVKAGQLLGLYGATSMDDISD-GLASEAHEIAKASKVGLRIEA 258

Query: 247 AALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
             +P+ P ++    +LG + L++A  G     +      + L AL +   G    +IGEV
Sbjct: 259 KLVPLAPELKQAAAMLGKEPLDYALYGGEDYQLVFTIGREKLQALSAVDFGVPLTVIGEV 318

Query: 307 VE-RKGVRLAGLYGVKRTLDL 326
            E   GV+L    GV++ L  
Sbjct: 319 TEAADGVKLVMDDGVEQELAP 339


>UniRef50_B0R2T1 Hydrogenase expression/formation protein n=2 Tax=Halobacterium
           salinarum RepID=B0R2T1_HALS3
          Length = 339

 Score =  188 bits (477), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 82/325 (25%), Positives = 125/325 (38%), Gaps = 23/325 (7%)

Query: 23  FMEAFANPWLAEQEDQARL------DLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLA 76
           F +           D  RL      D   +      +A +TD   +             A
Sbjct: 10  FFDDHIAGRTGADRDDVRLGPTYGADFGVVAIADSVVAMATDPVFVLRALG-IERAAWFA 68

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
                +DVA+SG  P +L+    L      ET  A+       ARA G+++ TG T   +
Sbjct: 69  FHICVSDVALSGLSPAHLAVDLNLPPDTATETFDAIWEVFDREARALGVSLTTGHTGTYE 128

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR--EQLGLDG 194
            G           +    A           GD ++V+         +L +   ++L +  
Sbjct: 129 -GCSFPTVGGATALAVGAAEDVVTPTGAQPGDRVVVTKGPAVETTGMLGVLFGDRLPISA 187

Query: 195 ELVSDCAVLTPLIQTLRDIP------GVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
              +           +RD         V A+ DAT  G+   +HE AAA G G+ ++  A
Sbjct: 188 AAAAAARDRFADATPVRDAATMAAAGEVTAMHDATERGLANGLHELAAASGVGLSVARDA 247

Query: 249 LPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE 308
           +PV P VR VCE  G+DA   ++EG ++ AV+  + + VL AL     G  AA +G V  
Sbjct: 248 VPVLPGVRAVCEQFGMDAWAASSEGTVIAAVDPGSVDAVLGALGDE--GIPAADVGVVEA 305

Query: 309 RKGVRLAGLYGVKRTLDLPHAEPLP 333
             GV + G       L  P A+PL 
Sbjct: 306 GSGVTVDGD-----PLAEPAADPLW 325


>UniRef50_A9KBN8 Thiamine-monophosphate kinase n=5 Tax=Coxiella burnetii
           RepID=A9KBN8_COXBN
          Length = 320

 Score =  187 bits (475), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 65/308 (21%), Positives = 128/308 (41%), Gaps = 21/308 (6%)

Query: 18  LINSLF---MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGGN 71
           +I + F    +   N  +   +D A ++    + +  ++  S D+ V     P+  P  +
Sbjct: 8   IIENYFHRPKKPAKNVVVGIGDDAAVIE----IPKEQQVVISVDTLVEGVHFPINTPPRD 63

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  A+  + +D+A  GAIP  +     + +      LKA        A    ++++ GD
Sbjct: 64  LGHKALAVSLSDIASMGAIPHTVLLALTI-QKTNEIWLKAFAEGFFSLADRYQVSLIGGD 122

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
                      L I+    G IP N        T GD++ ++GT+GD G  +  L++   
Sbjct: 123 VTQGP------LCISITATGLIPKNEMICRNGATVGDLIYLTGTVGDAGLALALLKQNKK 176

Query: 192 LDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           +D  L++     TP I+    + G+ +       GV A + + A A   G ++    LP+
Sbjct: 177 IDPFLLTRLNCPTPRIEAGVALRGIASAAIDISDGVVADLEKMARASQVGAKIYVERLPL 236

Query: 252 KPAVRGVCELLG--LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
             +++  C L      AL   ++ +L   + +  +E +      H L  +   IGE+++ 
Sbjct: 237 SDSLKRYCPLKKAWEYALTSGDDYELCFTIPKERSEPLEEVF--HSLDCECRCIGEIIQG 294

Query: 310 KGVRLAGL 317
           + V +   
Sbjct: 295 ESVTVIDP 302


>UniRef50_C7NRE1 AIR synthase related protein domain protein n=4
           Tax=Halobacteriaceae RepID=C7NRE1_HALUD
          Length = 340

 Score =  186 bits (472), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 78/330 (23%), Positives = 130/330 (39%), Gaps = 21/330 (6%)

Query: 19  INSLFMEAFANPWLAEQED------QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI 72
           I++   ++   P L    +      Q  +D   L  E   +  +TD   I P        
Sbjct: 7   IDTETFDSVIAPHLGADREDVTIGPQHGVDFGVLSVEESAVVVATDPISILP-ELGFERA 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G++A+     DVAVSG  P +++    L   +  E L      MA+ A   G++IV+G T
Sbjct: 66  GRVALDIVLTDVAVSGIAPTHITVSLSLPPEMTDEELGQTWRGMADHAENLGVSIVSGHT 125

Query: 133 KVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN--LREQ 189
              +   ++  ++     +G               GD ++++   G   A +      E 
Sbjct: 126 ARYE--GIEYSWVGGATALGVGDPADIVRPDGANPGDAVVLATGPGAETAGLFATLFPEA 183

Query: 190 LGLDGELVSDCAVLTPLIQTLRDIPGVKA------LRDATRGGVNAVVHEFAAACGCGIE 243
           L L  + V+        I  + D     A      + D T GGV   + E A   G   +
Sbjct: 184 LELPAKTVATAQECVGDILGVADATTAAAAGELTAIHDTTEGGVIGGLTEMATGAGVTFD 243

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           +     PV+P V  VC+ +G+D     + G L+I      AE V+ AL +H  G  AA+I
Sbjct: 244 VRRDPAPVQPGVAAVCDAIGVDPWTVTSAGSLLITAPPATAESVVEALEAH--GTPAAVI 301

Query: 304 GEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
           G V E        +   +R ++ P ++P  
Sbjct: 302 GSVEECSDTSADVILDGER-VEPPESDPAW 330


>UniRef50_B9LTA0 AIR synthase related protein domain protein n=4
           Tax=Halobacteriaceae RepID=B9LTA0_HALLT
          Length = 330

 Score =  186 bits (472), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 90/327 (27%), Positives = 137/327 (41%), Gaps = 25/327 (7%)

Query: 25  EAFANPWLAEQEDQARLDLAQLVAEGD---RLAFSTDSYVI--DPLFFPGGNIGKLAICG 79
           +A A    A   D A +D+     E      LA +  + V+  DPL      +G+LA+  
Sbjct: 8   DALAEVLAATGADDAAVDMGPAYGEDAAAIDLAGTESTLVVAADPLSLAADAVGELAVHV 67

Query: 80  TANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGA 139
             NDVA SGA PR+L+    L +       + V   +  TAR  G+AIV G T+V+   +
Sbjct: 68  ACNDVAASGADPRWLTHTLFLPDD-DATRRRTVTQQVDATARDLGVAIVGGHTEVLP--S 124

Query: 140 VDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN--LRE---QLGLDG 194
           +++   +   +G     +  G      GD LL++   G     IL    RE   + G+  
Sbjct: 125 LERPLCSMTALGTTDRFVSSG--GAEPGDRLLLTKGAGIEATAILATDFREACAEAGVSA 182

Query: 195 ELVSDCAVLTPLIQTLRDIPGVKA----LRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
             +   A     +  + D   V+     + D T GG+   + E A+A G  + +    +P
Sbjct: 183 ATLDAAAGFLDEVSVVPDAAAVRDAATAMHDPTEGGLLTALVETASASGTVLSVERDRVP 242

Query: 251 VKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV--VE 308
           V+P  R  C+ LG+D L     G L+ AV     + V  AL +   G D   IGEV  V+
Sbjct: 243 VRPETRACCDALGVDPLATFGSGALLAAVPPERVDAVTDALAAA--GIDVGEIGEVRAVD 300

Query: 309 RKGVRLAG--LYGVKRTLDLPHAEPLP 333
                  G  L    R  + P  E  P
Sbjct: 301 DSEGSDDGHLLLDGDRIDEAPRDELYP 327


>UniRef50_C3N8T5 AIR synthase related protein domain protein n=11 Tax=Sulfolobus
           RepID=C3N8T5_SULIY
          Length = 318

 Score =  183 bits (466), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 68/311 (21%), Positives = 122/311 (39%), Gaps = 31/311 (9%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAIC 78
           IN           L         D A L  +G+ L   +D     P+     + G L+I 
Sbjct: 8   INKFIYNLPTGDCLTCP--SIGEDAAVLETKGEYLIVHSD-----PITEAKSDNGFLSIA 60

Query: 79  GTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRG 138
              ND+ + GA  R+++   +L     +  L  +++ ++E     G  +V G T+V    
Sbjct: 61  VACNDINMKGAQCRWVNSVILLS---DISHLDGIISGISEACNLIGCKVVGGHTEVTSNV 117

Query: 139 AVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN-----LREQLGLD 193
             D   + T  MG   +N     +++  G  +++ G+ G  G  IL      L  + G+ 
Sbjct: 118 KQD--IVITTAMGT--SNKFLNYKSVKEGMKVVLVGSPGIEGTWILAKDYSELLLEKGVS 173

Query: 194 GELVSDCAVLTPLI----QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAAL 249
            E++         I    + L  +  V A+ DAT GGV   + E A A G  + ++   +
Sbjct: 174 REVIEKAKGFKMDIIVQQRALSILDYVAAMHDATEGGVMQALLEIAKATGYTVLINLDKI 233

Query: 250 PVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
            ++   + + + L +D L   + G     V  N  E++L  +       +A +IGE+   
Sbjct: 234 GLRYETKIITKALNIDPLKLISSGS--FIVISNHPEKILERIS------EAYVIGEIKRG 285

Query: 310 KGVRLAGLYGV 320
             V      G 
Sbjct: 286 DSVLEIKGVGT 296


>UniRef50_C8WRZ3 Thiamine-monophosphate kinase n=2 Tax=Alicyclobacillus
           acidocaldarius RepID=C8WRZ3_ALIAD
          Length = 323

 Score =  181 bits (460), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 74/290 (25%), Positives = 120/290 (41%), Gaps = 23/290 (7%)

Query: 40  RLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVSGAIPRYLS 95
             D   +V  G RLA +TD+ V    F         +G  A+    +D+A  G  P +++
Sbjct: 25  IGDDCAVVDGGGRLAVTTDAVVEGVHFRRDTMSPPQMGYRAMAAAVSDIAAMGGQPAWIT 84

Query: 96  CGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
               +    P E + A+   ++E A A G ++V GD    Q      L+++   +G +  
Sbjct: 85  VALAVPPSWPQEDVVAIYDGVSEAAAAFGASVVGGDVVSTQG----PLWMSITAVGRVER 140

Query: 156 NIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNLREQLGL-DGELVSDCAVLTPLIQTLR 211
                      GDVL V+G+LG   A    +L  R    +    LV      TP I   R
Sbjct: 141 --PVTRAGARPGDVLFVTGSLGGSAAGLDILLGRRAGSAIAQAVLVERHRRPTPRIAFGR 198

Query: 212 DIP--GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNF 269
           +    G  AL D +  G+ + ++E A A G  +      +P++P V      +G D L +
Sbjct: 199 EAARLGATALDDISD-GLASELNEIAEASGVRLLFEGDRVPIQPEVTEYARAVGKDPLEY 257

Query: 270 A----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLA 315
           A     + +LV    R+   ++LA   +  +G     IG V E  GV + 
Sbjct: 258 ALFGGEDYELVGTAPRDVFARLLAV--APVVGTPITAIGRVEEGDGVVMR 305


>UniRef50_A6W2L4 Thiamine-monophosphate kinase n=2 Tax=Marinomonas
           RepID=A6W2L4_MARMS
          Length = 316

 Score =  180 bits (458), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 74/316 (23%), Positives = 129/316 (40%), Gaps = 25/316 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARL--DLAQL-VAEGDRLAFSTDSYVIDPLFFPGG--- 70
           +LI ++F  +         +    +  D AQ+ V +G  L FS D+ +++   FP     
Sbjct: 5   ELIQNIFQASVMASTQGRGDLLLGIGDDCAQVQVPQGQSLVFSMDT-LVEGRHFPFDADP 63

Query: 71  -NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            +IG  A+    +D+A  GA P + + G  + E  P + L  +   MAE A   G+A+V 
Sbjct: 64  VDIGYRAVASCVSDLAAMGAKPAFFTLGLTIPESDP-QWLAGLAQGMAELAEPIGLALVG 122

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           GDT          L I     G +  ++         GD + V+G LGD  A +  +  +
Sbjct: 123 GDTTKGP------LTITLQVHGYVEPDMAVKRSGAKLGDDIYVTGVLGDAAAAVPIVTGE 176

Query: 190 LGLDGELVSDCAVLTP-----LIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
           L +  E               LI  +     V A+ D +  G+   +     A G G  +
Sbjct: 177 LQVSSERFDYFYDRYWRPQPRLIVGMALKRVVHAMMDISD-GLAQDIQHILKASGVGANI 235

Query: 245 SEAALPVKPA-VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + + +P+    +R   E     AL   ++ +L     ++ A ++  AL +  L      +
Sbjct: 236 NASRMPISAELLRWQPESAVALALTGGDDYELCFTAPKDQAAEI--ALITQTLSLPCTKV 293

Query: 304 GEVVERKGVRLAGLYG 319
           GE+V  +G  + G  G
Sbjct: 294 GEIV-AEGFVIQGYDG 308


>UniRef50_Q9V1N8 Probable thiamine-monophosphate kinase n=3 Tax=Pyrococcus
           RepID=THIL_PYRAB
          Length = 310

 Score =  180 bits (457), Expect = 6e-44,   Method: Composition-based stats.
 Identities = 60/297 (20%), Positives = 109/297 (36%), Gaps = 20/297 (6%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAIC 78
           I SLFM+ F    L +     +L+ + L+   D L + TD     P F    + G+  + 
Sbjct: 10  IISLFMKHFERHSLGDDAGFIKLNNSWLLVTSDMLVWKTD----VPDFMTPEDAGRKVVT 65

Query: 79  GTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRG 138
              +D+A  G  P        +   +  + L+ +   + E ++   + IV+GDT      
Sbjct: 66  MNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDT-----N 120

Query: 139 AVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVS 198
             D + I+   +G               GD++ V+G LG     +L       +  E+  
Sbjct: 121 EADDIIIDGGSLGI--GKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPREIEE 178

Query: 199 DCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGV 258
                   ++    +  +         G++  + E A A    I + E  LP+  +V+ +
Sbjct: 179 KARNPRARVEEGVKLSSLANSAIDISDGLSKELWEIANASNVRIIIEEERLPISDSVKEI 238

Query: 259 CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLA 315
                  AL    E +L+  + R   E+         L  D  +IG V    GV + 
Sbjct: 239 VSDPVKVALASGEEFELLFTIPREKVEE---------LDIDFKIIGRVEGGNGVYIK 286


>UniRef50_C5A3X6 Thiamine monophosphate kinase (ThiL) n=4 Tax=Thermococcus
           RepID=C5A3X6_THEGJ
          Length = 319

 Score =  179 bits (455), Expect = 1e-43,   Method: Composition-based stats.
 Identities = 76/330 (23%), Positives = 117/330 (35%), Gaps = 32/330 (9%)

Query: 14  AMQQLINSLFMEAFANPW---LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
            M+  I  LF+          L +     RL    LVA  D L   TD     P      
Sbjct: 1   MMESEIIELFIRHLKRQGDLPLGDDAGALRLGDRWLVATNDMLVRKTD----VPDIMTPE 56

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G  A+    +D+A  GA P        +   L  + L+ +   + E     G+ +++ 
Sbjct: 57  QVGFKAVTMNVSDMASMGAEPLGFLFSLGIPGDLDSDYLEGIARGIGEALDFYGLPVLSA 116

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT        D L I+ A +G               G+++ V+G LG   A  L  +  L
Sbjct: 117 DT-----NEADDLIIDGAALGITER--LLTRSGAKPGELVCVTGDLGRALAGYLVWKNGL 169

Query: 191 GLDGELV----SDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
            +   +              ++   ++  V +       G+   ++  A     GIE+  
Sbjct: 170 EVSDAVRKPLYEKFLEPRARVREGSELSKVASSAIDISDGLAKELYLLAEMSQVGIEVRP 229

Query: 247 AALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            +LP+   V  V ELLGLD     L    E +LV  V     E          L  D ++
Sbjct: 230 ESLPLGKGVEEVAELLGLDPFEIALASGEEFELVFTVAPEFVES---------LNFDFSV 280

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           IG V   KG+ L    G KR +     E L
Sbjct: 281 IGRVTRGKGIYLVDDSG-KRVMPKLGWEHL 309


>UniRef50_Q0W120 Putative thiamine monophosphate kinase n=2 Tax=Euryarchaeota
           RepID=Q0W120_UNCMA
          Length = 322

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 80/320 (25%), Positives = 124/320 (38%), Gaps = 38/320 (11%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTD--SYVID-PLFFPGGNIGK 74
           LI     +   +P+L +       D A +    D L  +TD    V D P    G +IG 
Sbjct: 11  LIRR-IGKILQSPYLGD-------DCAVIDNGNDYLVVTTDMLHRVTDFPREMTGEDIGW 62

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
           +++  + +DVA  GA P  +     +     +E +  + T M   A+  G  I+ GDT  
Sbjct: 63  MSVAVSLSDVAGMGARPVGVVAAIGIPGDTDIEFIDGIATGMRNCAKCYGTDIIGGDTDQ 122

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA---TILNLREQLG 191
            Q     +L I T   G +  +          GD+L V+G LG   A    +   RE   
Sbjct: 123 HQ-----ELTIVTTAFGRVNKDQVKLRSGAKVGDLLCVTGYLGTTAAGFKVLTGEREASP 177

Query: 192 LDGELVSDC----AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
            D +++                L   PGV A+ D +  G+   V+E + A   G  +   
Sbjct: 178 EDRQILFRSFFRPEPRLGEGMILAQYPGVTAMMDVSD-GLGKSVYELSVASKVGFIVYAD 236

Query: 248 ALPVKPAVRGVC----ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           ALPV+   R V     ELL + A+ F  E +L+  V  +    +         G D  +I
Sbjct: 237 ALPVREEARKVARSRTELLDM-AICFGGEFELLFTVNPDEVGNI--------KGVDFTVI 287

Query: 304 GEVVERKGVRLAGLYGVKRT 323
           G+V E  G+ L         
Sbjct: 288 GKVTE-SGLVLDDRGARTEI 306


>UniRef50_UPI0001BC315E hydrogenase expression/formation protein n=1 Tax=Butyrivibrio
           crossotus DSM 2876 RepID=UPI0001BC315E
          Length = 311

 Score =  176 bits (448), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 60/291 (20%), Positives = 105/291 (36%), Gaps = 35/291 (12%)

Query: 62  IDPLFFPGGNIGKLAICGT----------------ANDVAVSGAIPRYLSCGFILEEGLP 105
           ID   F  G+I  L  C T                AN++ VSG     +   F+L +   
Sbjct: 27  IDAASFAVGDIHVLTACATGLTDCAIAPETAVYKAANNIWVSGGELLGIEASFMLPKNYN 86

Query: 106 METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLT 165
              LKA    +          +  G T+V     V +  I+ A  G            + 
Sbjct: 87  EYNLKAYTKRVKAACDKCKTTLAGGHTEVTD--GVKRFCISVAATGIAGT-TPVNIHNVK 143

Query: 166 AGDVLLVSGTLG-DHGATILNLREQLG-----LDGELVSDCAVLTPLIQTLRDI-----P 214
            G  ++V+  +  +  A I++  + +         E +S        +    +       
Sbjct: 144 PGMDIIVTKWIALEEAAMIVSNEDNMAKLCEHFSNEYMSVTGQYADWLTVRDEAAVAMKH 203

Query: 215 GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGK 274
           GV A+ D + GG+   + +FA   GCG E+    +P++     + E   L+     + G 
Sbjct: 204 GVAAMHDISEGGIFTALWDFAEGSGCGFEVDLKRIPLRQETVEIAEFFHLNPYTMKSSGS 263

Query: 275 LVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLD 325
           ++IA   +    ++ AL+    G  A +IG   +  G  L     + R LD
Sbjct: 264 IIIAC--DNGTDMVNALNEE--GIPAVIIGRTTDNNGKILRNEDEI-RYLD 309


>UniRef50_Q3ARA0 Thiamine-monophosphate kinase n=11 Tax=Chlorobiaceae
           RepID=Q3ARA0_CHLCH
          Length = 369

 Score =  176 bits (446), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 75/350 (21%), Positives = 131/350 (37%), Gaps = 52/350 (14%)

Query: 18  LINSLFMEAFANPWLAEQE---DQARLDLAQLVAEGDRLAF-STD----SYVIDPLFFPG 69
           LI+++       P LA           D A +      +   +TD    S   D L  P 
Sbjct: 9   LIDTI--AHLVQPTLANAPTLLQGIGDDCAIMQPTAGMVEVATTDLLVESVHFDLLTTPL 66

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            ++G  AI    +D+    A+PRY      L      + ++ +   M   A+A GIAI  
Sbjct: 67  SHLGSKAISVNVSDICAMNALPRYALVSLALPPTFSKKMVEELYGGMVHAAQAYGIAIAG 126

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL----- 184
           GDT   + G    L I+   +G                D+L V+GTLG   A +      
Sbjct: 127 GDTSASRSG----LMISITAIGEALPTQLTRRSGAQLDDLLCVTGTLGGSMAGLKLLMRE 182

Query: 185 ------NLREQLGLDGELVSDCAVLTPLIQ------------TLRDIPGV--KALRDATR 224
                 +LR    ++  L++D      L+Q             L    G+   A+ D + 
Sbjct: 183 KEIMLEHLRNNEPVNRNLLADLDEYRELMQRHLLPTARLDVVRLFHRLGIQPTAMIDISD 242

Query: 225 GGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFA----NEGKLVIAVE 280
            G+++ V        CG  L E+ +P+    R + + +  + L +A     E +L+  + 
Sbjct: 243 -GLSSEVQHICRHSNCGALLHESRIPIHATTRQLADEMQEEPLTWALTGGEEYQLLFTLP 301

Query: 281 RNAAEQVLAALHSHPLGKDAALIGEVV-ERKGVRLAGLYGVKRTLDLPHA 329
               +Q+          +D  +IG +    +G+ L  ++G++  L   H 
Sbjct: 302 EATYQQL-------AHERDIHVIGTITPTNEGMVLEEMFGIRIDLTTIHG 344


>UniRef50_A3HUE4 Hydrogenase expression/formation factor related protein n=1
           Tax=Algoriphagus sp. PR1 RepID=A3HUE4_9SPHI
          Length = 350

 Score =  176 bits (446), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 63/312 (20%), Positives = 116/312 (37%), Gaps = 21/312 (6%)

Query: 38  QARLDLAQLV-AEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSC 96
              +D+A      G  +A ++D   + P          L++   AND+A +G  P+Y   
Sbjct: 32  GFGVDVAITSLPGGLAMAATSDPLSLIP-SLGLQESAWLSVHLMANDMATTGFAPQYGQF 90

Query: 97  GFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN 156
              L + L           +    +  G+AI  G T  VQ G           +   P +
Sbjct: 91  VLNLPDSLSNADFSTYWGYIDRFCKEIGVAITGGHTGFVQ-GQNSTFAGGGTLITIAPES 149

Query: 157 IHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAV----LTPLIQTLRD 212
               A     GDV+LV+ +       IL +     +  +L +D             +L+D
Sbjct: 150 EMICATGAEEGDVILVTKSCAMTATAILGMSFPETVKNKLGTDVYESACQQFYQTSSLKD 209

Query: 213 ----------IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELL 262
                      P + A+ D T GGV   ++E   A G G  +    +PV      + +L 
Sbjct: 210 GLIAAGESEKFPEITAMHDVTEGGVLGAIYEMLIASGKGGMIENDLIPVGEIASQISKLF 269

Query: 263 GLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV-ERKGVRLAGLYGVK 321
            LD       G ++I+   + + Q++  L +        ++G+V+ + +G+R++      
Sbjct: 270 DLDPRYCVGAGAMIISCRPDKSAQLIDRLGNEN--ISCTVVGKVLGQDQGIRISEGESSS 327

Query: 322 RTLDLPHAEPLP 333
             L+    +P  
Sbjct: 328 -LLEYKETDPYW 338


>UniRef50_B3QYZ8 Thiamine-monophosphate kinase n=1 Tax=Chloroherpeton thalassium
           ATCC 35110 RepID=B3QYZ8_CHLT3
          Length = 373

 Score =  176 bits (446), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 74/345 (21%), Positives = 126/345 (36%), Gaps = 50/345 (14%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLV--AEGDRLAFSTD----SYVIDPLFFPGGN 71
           LI  +   A           +   D   ++  ++ +    +TD        D L  P  +
Sbjct: 14  LIEKISAIASQTESQMNSLKKGIGDDCAILEFSDTEYQVVTTDLLIEQIHFDLLTTPMEH 73

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  AI    +D+    A+P Y      L E L +E ++++   M+  A+  G+AIV GD
Sbjct: 74  LGAKAISVNVSDICAMNALPTYAVVSIALSEKLSVEMVESLYKGMSNAAKEYGLAIVGGD 133

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD-HGATILNLREQL 190
           T     G    L I+   +G +         T   GDV+ VSG LG  H    + +RE+ 
Sbjct: 134 TSASTAG----LVISVTIVGKVKKEKVARRSTAKPGDVVCVSGVLGGSHAGLKVLMRERK 189

Query: 191 GLDGELVSDCAV---LTPLIQTLRDIPGVK---------------------ALRDATRGG 226
            +   L  D +V     P I   +D                          A+ D +  G
Sbjct: 190 LMLDNLKEDGSVDENYRPEIADYQDAVSRHLLPKARLDIVRLFERRGIVPTAMIDISD-G 248

Query: 227 VNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERN 282
           + + +         G  + E   P+    R V +    +    AL    + +L+  +   
Sbjct: 249 LASEIKHICKESKTGAIIEENKFPIMSHARHVADEFEEEATTYALYGGEDYELLFTLSPE 308

Query: 283 AAEQVLAALHSHPLGKDAALIGEVV-ERKGVRLAGLYGVKRTLDL 326
            AE++           D  +IGE+  E  GV +  ++   R +DL
Sbjct: 309 DAEKLQET-------DDVKIIGEIKPEAYGVVMLDMFA--REIDL 344


>UniRef50_D2M233 Thiamine-monophosphate kinase n=1 Tax=Bacillus cellulosilyticus DSM
           2522 RepID=D2M233_BACS4
          Length = 327

 Score =  175 bits (444), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 66/304 (21%), Positives = 112/304 (36%), Gaps = 28/304 (9%)

Query: 40  RLDLAQLVAEGDRL--AFSTDSYV----IDPLFFPGGNIGKLAICGTANDVAVSGAIPRY 93
             D A +     ++    + D+ V          P  +IG  A+    +D+A  GAIP+Y
Sbjct: 25  IGDDAAIYGHDKKMESVVAVDTMVEGIHFTKQTMPMKSIGHKALAVNISDIAAMGAIPQY 84

Query: 94  LSCGFILEE-GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
                 + +     + L  +   M E A    + ++ GDT        D L I+   +G 
Sbjct: 85  YLVSIAIPKTSWKKKELNDIYNGMNELATVWSMDLIGGDTVSTN----DALVISVTVIGK 140

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRD 212
           +             GDV+ V+G LG     +  L E+     E + D  +L  L    + 
Sbjct: 141 VEKERRLLRSNARCGDVVFVTGELGLSAYGLQALLEK---GYENIDDDELLPYLQAHQKP 197

Query: 213 IPGVKALR-----------DATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCEL 261
            P V+A R           +    G+ +   E A A    +EL  AA+P    ++   + 
Sbjct: 198 DPHVRAGRLLANCGYRIALNDISDGLASEAKEIADASQVTVELDWAAIPTTNKLKEYPQE 257

Query: 262 LGLDALNFANE-GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV 320
              + L +  E  KLV  + +   E++ AA  +H L      IG ++      L      
Sbjct: 258 KQEEWLLYGGEDFKLVGTIGKENWEKLKAAFQAHSL--PIFKIGSILTGNSEVLLKKENK 315

Query: 321 KRTL 324
           +  L
Sbjct: 316 REVL 319


>UniRef50_Q2RZV6 Thiamine-monophosphate kinase n=1 Tax=Salinibacter ruber DSM 13855
           RepID=Q2RZV6_SALRD
          Length = 360

 Score =  174 bits (442), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 80/343 (23%), Positives = 128/343 (37%), Gaps = 48/343 (13%)

Query: 19  INSLFMEAFANPWLAEQEDQARL-----DLAQLVAEGDRL-AFSTDSYV----IDPLFFP 68
           I    + A     L E  D   +     D A    + DR+   +TD+ V     D  F P
Sbjct: 15  IGEFGLIALLRDTLGEPTDDTIVSGIADDAAVYRTDEDRVHVMTTDTLVEGVHFDRAFMP 74

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
             ++G  A+    +DV    A PRY +    + + + +E +  V   + +   A  + IV
Sbjct: 75  MEHLGFKALSVNVSDVVAMNASPRYATVSIGIPQNVSVEMITTVYEGLKQACDAYDMHIV 134

Query: 129 TGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA---TILN 185
            GDT          L ++ + +GA              GD + V+G LG   A    +L 
Sbjct: 135 GGDTNASH-----GLSLSISVVGAAAEEDVVYRTGAQVGDKICVTGDLGSSYAGLKVLLR 189

Query: 186 LREQLGL-DGELVSDCAVLTPLI-QTLRDIPGVKALRDATR------------GGVNAVV 231
            RE+L   + +   D    + +I + L     +K +RD                G++A V
Sbjct: 190 NRERLQEQEEDFEPDLDPYSYVIRRHLAPPAQLKTVRDWGDAGVQPHALIDISDGLSAEV 249

Query: 232 HEFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQV 287
           H    A   G +L E ALP+ P  R      G D    AL    + +LV  +     E  
Sbjct: 250 HHICEAGDLGAQLYEPALPIDPETRNTATDFGEDVTIYALFGGEDYELVFTIP----EDE 305

Query: 288 LAALHSHPLGKDAALIGEVVE----RKGVRLAGLYGVKRTLDL 326
           L AL          ++GE+VE       +++   +G    L  
Sbjct: 306 LDALDPQTY----TVVGEIVEPDDPEHPIKIQRAHGENVPLQP 344


>UniRef50_D1B5R8 AIR synthase related protein n=3 Tax=Synergistaceae
           RepID=D1B5R8_THEAS
          Length = 326

 Score =  173 bits (440), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 69/279 (24%), Positives = 113/279 (40%), Gaps = 18/279 (6%)

Query: 39  ARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGF 98
              D A +   GDR       +  DP+       G+L +   ANDVA  G  P +L+   
Sbjct: 37  VGEDAAVIKWPGDRYLI----FTSDPIVGAVKGAGRLLVRVNANDVAAKGGEPMFLAVTM 92

Query: 99  ILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH 158
           I+   + +E   A++  +       G+A+  G T+   R   D   +  A +G+  A   
Sbjct: 93  IIPPSMGVEAASAIMEEIHRECCRIGVAVAGGHTEFNDR--YDSPVLMGAMIGS--AQRV 148

Query: 159 WGAQTLTAGDVLLVSGTLGDHGATILNL-REQLG--LDGELVSDCAVLTPLIQTLRDIPG 215
             A  +  G ++LV+  LG  G +IL   RE L   L GE + +      L   + +   
Sbjct: 149 LSASEVRPGHLVLVTKHLGIEGMSILAHDREDLLGFLSGEELEEVRSWGELTSVVPEAAL 208

Query: 216 VK----ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFAN 271
           ++     + D T GG    + E  +  G  + L E  LP+ P  R     LG D     +
Sbjct: 209 LRDLASFMHDPTEGGFLGGLGEVESLTGLKVRL-EGDLPIHPLTRRAASQLGFDPTCLIS 267

Query: 272 EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
            G L+  +     E+    LH    G   +++GEV++  
Sbjct: 268 SGSLLAFLPPKGLEEAERRLHRA--GIPWSVVGEVLDEP 304


>UniRef50_C0ZK37 Thiamin-monophosphate kinase n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZK37_BREBN
          Length = 338

 Score =  172 bits (437), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 54/258 (20%), Positives = 97/258 (37%), Gaps = 21/258 (8%)

Query: 66  FFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGI 125
                +IG  A+    +DVA  G + RY      +      +  + +   + E  +A G+
Sbjct: 60  TMNPSDIGYKAVISNVSDVAAMGGVARYALVSIAVSPQWTPDECQQIYEGIYEACQAYGV 119

Query: 126 AIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN 185
            ++ GDT        D L ++   +G +             G ++ V+G +G   A +  
Sbjct: 120 RVIGGDTVSAP----DALHLSVTVLGEVEKGRAIRRSQAKPGQLVFVTGHVGTSAAGLHL 175

Query: 186 LREQLGLDGELVSDCAVLTPLIQT----------LRDIPGVKALRDATRGGVNAVVHEFA 235
           L +    +  + +    L    Q           L +     AL D +  G+ + + E A
Sbjct: 176 LLQGETAERGVSASWETLMDAHQRPVAQIKAGRLLLESGACSALNDVSD-GLASELWEIA 234

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFA----NEGKLVIAVERNAAEQVLAAL 291
            A G  I +  A +P+   VR     +  D L +A     + +LV  + ++  E V    
Sbjct: 235 EASGVSILVDAATVPIHDEVREYARHVEKDPLEWAFYGGEDYQLVGTLAKSHYEAVSKQF 294

Query: 292 HSHPLGKDAALIGEVVER 309
                G    +IGEVVE+
Sbjct: 295 --AVSGVRFTVIGEVVEK 310


>UniRef50_B0TDV9 Thiamine-monophosphate kinase n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDV9_HELMI
          Length = 373

 Score =  171 bits (434), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 71/314 (22%), Positives = 114/314 (36%), Gaps = 42/314 (13%)

Query: 32  LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVS 87
           L   +D A +D    V  G  L  +TD  V    F         +G+ A+    +D+A  
Sbjct: 50  LGIGDDAAVID----VPGGKPLLVTTDMLVEGVHFLWSPIRRRLLGRKALAVNISDIAAM 105

Query: 88  GAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINT 147
           G IP +      +     +E ++ +   M E A   G+ +  GDT        DK  IN 
Sbjct: 106 GGIPAWAFLSIGVPASAKVEEVEGLYAGMGEMAAQFGVELAGGDTVRS-----DKWVINV 160

Query: 148 AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCA------ 201
             +G        G      GD++LV+GT+GD  A +  L  +  +      D        
Sbjct: 161 TLLGLAVK-APIGRSGGRPGDLILVTGTVGDAAAGLHLLLMETKMSQAEKMDAQMREAPI 219

Query: 202 ----------------VLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
                                 + L D  GV A+ D +  GV++ VH      GCG  + 
Sbjct: 220 GEADRQALLLRHLDPIPRVAEARALVDYGGVTAMMDVSD-GVSSEVHHLCRNSGCGARID 278

Query: 246 EAALPVKPAVRGVCELLGLDALNFANEG----KLVIAVERNAAEQVLAALHSHPLGKDAA 301
            A LP+ PAVR +    G +   +A  G    +L+          ++  +     G    
Sbjct: 279 LANLPISPAVRRLARREGREVFAWALSGGEDYELIFTAPEERVPGLIDHVRRET-GTGVT 337

Query: 302 LIGEVVERKGVRLA 315
           +IG + +     +A
Sbjct: 338 VIGRLTDGTAGVMA 351


>UniRef50_A4J8J0 Thiamine-monophosphate kinase n=1 Tax=Desulfotomaculum reducens
           MI-1 RepID=A4J8J0_DESRM
          Length = 334

 Score =  170 bits (432), Expect = 5e-41,   Method: Composition-based stats.
 Identities = 73/324 (22%), Positives = 119/324 (36%), Gaps = 26/324 (8%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG-----NI 72
           LI+ L      +P   +       D A L   G +    T   +++ + F         +
Sbjct: 12  LIDLLNKNMLYDP--EKVIAGIGDDAAVLKPPGTKWQLLTTDMMMENIHFRLDWSQYYQV 69

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +DVA  G  P +      + E   +E ++ +   + E A    + +V GDT
Sbjct: 70  GYKALAVNISDVAAMGGYPSHAVVSVGIPEETRVEDIEELYRGLKEMACRFKVNLVGGDT 129

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L IN A MG +             GD++  +G LG   A +  L      
Sbjct: 130 VKSPG----PLVINIALMGEVEEGRAVFRSGAKPGDLIYTTGFLGTSAAGLYILSHNGDY 185

Query: 193 DGELVSDC-------AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
             EL                  + L ++ GV AL D +  G+ A + E   A   G  + 
Sbjct: 186 PVELKEKVIRSHLLPEPRVAAARILSELEGVTALDDNSD-GLAAELREICRASSAGCLIR 244

Query: 246 EAALPVKPAVRGVCELLGLDALNFANEG----KLVIAVERNAAEQVLAALHSHPLGKDAA 301
           E +LPV P V  +  L G + L++  +G    +L+  +     E +  AL     G    
Sbjct: 245 EKSLPVLPEVEQLACLTGRNTLDWIMDGGEDYELLFTLRPERQEYIENALGKE--GILYK 302

Query: 302 LIGEVV-ERKGVRLAGLYGVKRTL 324
            IG +    +G+ L    G K T+
Sbjct: 303 AIGIITHSSEGMVLEKEDGAKETI 326


>UniRef50_Q3II30 Thiamin-monophosphate kinase n=3 Tax=Alteromonadales
           RepID=Q3II30_PSEHT
          Length = 326

 Score =  169 bits (429), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 63/307 (20%), Positives = 118/307 (38%), Gaps = 25/307 (8%)

Query: 17  QLINSLFMEA---FANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGG 70
           +LIN  F        +  L   +D A +     V +  +LA +TD+ V    FF      
Sbjct: 7   ELINRYFKGRGITRRDVNLGIGDDCALV----TVPQNCQLAITTDTLVAGVHFFDDIEPR 62

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G  A+    +D+A  GA P ++S    L   +  + ++ +   M E A    + I+ G
Sbjct: 63  ALGHRALAVNLSDLAAMGAEPTWVSIALTLP-SIDQQWIEELTDGMHEIAEYFNVQIIGG 121

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I     G +P            GD + V+G LGD G  I + ++ L
Sbjct: 122 DTTQGP------LSITICAKGTVPEGTALCRNGAKVGDWIFVTGPLGDAGLAIESRKQGL 175

Query: 191 GLDGE----LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
            ++ E    +       TP +   + + G+ +       G+ A +            ++ 
Sbjct: 176 TIEPEHLKHIKKRLNFPTPRVAAGQVLRGLASSAIDISDGLLADLGHILNMSQVSATVNI 235

Query: 247 AALPVKPAVRGVCELLGLDA--LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
            ++P   A++   +        LN+ ++ +L+  V  +    +   L     G +A  IG
Sbjct: 236 ESIPTSDAMKASLDFEQQLPFILNYGDDYELLYTVPDSNKSMLDVKLRQ--YGVEAICIG 293

Query: 305 EVVERKG 311
           ++   +G
Sbjct: 294 QIKSGEG 300


>UniRef50_O27447 Probable thiamine-monophosphate kinase n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=THIL_METTH
          Length = 327

 Score =  169 bits (428), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 66/323 (20%), Positives = 123/323 (38%), Gaps = 29/323 (8%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP----GGN 71
           ++LI+ +   A         E     D A L+  G+     T   +++   FP      +
Sbjct: 11  KKLISRIISRA--RSVFGSSEVMGLGDDAALIDAGEEFLVLTSDLLLETRHFPDPERPRD 68

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G   +    +D+A  G+ P        L + L +E   +++  + E        ++ GD
Sbjct: 69  MGWKTVTVNMSDLAAMGSRPEGFILSVALPD-LELEFFDSLMDGVIEACCHYQAPLIGGD 127

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNLRE 188
           T        D++ ++   +G    ++         GD++ V+G LG   A    IL+ R+
Sbjct: 128 T-----NEADEIILSGTAIGRAEKDMVLMKSGARPGDLVAVTGPLGVGAAGTELILSGRD 182

Query: 189 QLGLDGELVSDCAVLTPLIQ--TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
             G +  +      +  + +   L +   V +  D T  G+ + + E   A G G+ + E
Sbjct: 183 TGGFENAVERSLRPVARIEEGLILAESGLVSSATDITD-GLVSELGELMDASGTGMRIYE 241

Query: 247 AALPVKPAVRGVCELLGLDALNFANEG----KLVIAVERNAAEQVLAALHSHPLGKDAAL 302
             LP+   V  +  +LG D L  A       +LV        E++   +  H       +
Sbjct: 242 DRLPLGREVPEIASILGRDPLELALYYGEDFELVFTAPPTGMEELSDMMELH-------V 294

Query: 303 IGEVVERKGVRLAGLYGVKRTLD 325
           IGEV    G+ +    GV   L 
Sbjct: 295 IGEVTVGGGIEMVDKDGVTYKLH 317


>UniRef50_D0SP02 Thiamine-monophosphate kinase n=1 Tax=Acinetobacter junii SH205
           RepID=D0SP02_ACIJU
          Length = 305

 Score =  168 bits (426), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 61/304 (20%), Positives = 107/304 (35%), Gaps = 25/304 (8%)

Query: 17  QLINSLFMEA-FANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGGNI 72
            +I+  F  A   +  L   +D A L          +L   TD+ V     PL      +
Sbjct: 5   SIIDRYFKRASHQDVSLGIGDDSAIL----TPLTSQQLVICTDTLVAGRHFPLDTSAHAV 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  ++    +D+A  GA P  +     L   +    L      + E      +A++ GDT
Sbjct: 61  GWKSVAVNLSDIAAMGAQPHSILLALSLP-SVDETWLAEFSRGLFECCDQFNVALIGGDT 119

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                    +L I    +G I             GD + VSG +GD    + +L   L  
Sbjct: 120 TQSS-----QLTITVTALGWIEQGQAITRAGAQVGDYICVSGQVGDAAYGLHHLGHTLQQ 174

Query: 193 DGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVK 252
             +  +       L Q L+      ++ D +  G+   +     A G G  L    LP+ 
Sbjct: 175 RLDYPT---PRCQLGQRLK--GRATSMIDVSD-GLAQDLGHILKASGVGATLFLDRLPID 228

Query: 253 PAVRGVCELLG-LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG 311
            A++ + +      AL   ++ +L   +     E+    L  H       +IGE+ ++ G
Sbjct: 229 SALKALDQQQAWQYALAGGDDYELCFTISPQKFEE----LSRHQSDVPFTIIGEITQQTG 284

Query: 312 VRLA 315
           +   
Sbjct: 285 LLFK 288


>UniRef50_Q0ABQ2 Thiamine-monophosphate kinase n=3 Tax=Gammaproteobacteria
           RepID=Q0ABQ2_ALHEH
          Length = 321

 Score =  167 bits (424), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 82/314 (26%), Positives = 114/314 (36%), Gaps = 27/314 (8%)

Query: 17  QLINSLFMEAFANPW--LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGN 71
           QLI S F          L   +D A L  A     G  L    D+ V    F    P   
Sbjct: 5   QLIRSYFQPDARGEGVVLGVGDDAALLQPAP----GQLLVTCVDTLVAGVHFPEDAPPDA 60

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  A+    +D+A  GA PR+      L E +    L A  + +   A    +A+V GD
Sbjct: 61  VGHKALAVNLSDLAAMGARPRWFQLALTLPE-IDEAWLAAFSSGLHRLAAEQDVALVGGD 119

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL- 190
           T          L I    MG +            AGD L V+GTLGD    +   +  + 
Sbjct: 120 TTRGP------LTITVQAMGEVAPAQALRRTGARAGDRLYVTGTLGDAAQGLALWQRGVR 173

Query: 191 -----GLDGELVSDCAVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
                   G L+      TP +          +A  D + G +  + H      G G  L
Sbjct: 174 SAGGDDPAGFLIDRLHRPTPRMAAGRAAAGLARAAIDISDGLLADLGHLLEGGEGLGAVL 233

Query: 245 SEAALPVKPAVRGVCE--LLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
              +LP+ PA R  CE  L G  AL+  ++ +L+ AV          AL   P G     
Sbjct: 234 QADSLPLSPAYRAHCEDSLPGRAALSGGDDYELLFAVAPENEAAFQTALQHVPAG--CTC 291

Query: 303 IGEVVERKGVRLAG 316
           IG + E   + L G
Sbjct: 292 IGWITEDSAITLQG 305


>UniRef50_D0MD26 Thiamine-monophosphate kinase n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MD26_RHOM4
          Length = 358

 Score =  167 bits (424), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 77/339 (22%), Positives = 122/339 (35%), Gaps = 46/339 (13%)

Query: 18  LINSL--FMEAFANPWL--AEQEDQARLDLAQLVAEGDRLAFSTDSYV----IDPLFFPG 69
           LI+ L   +   ++P L     +D A   L     E      +TD+ +     D L  P 
Sbjct: 16  LIDRLQTIVADLSDPDLIMGIGDDAAVYRLPD---EETVHVITTDALLEGVHFDRLMTPM 72

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            ++G  AI    +DV    A PRY +    +   + +E ++A    +       G+ +V 
Sbjct: 73  EHLGYKAIAVNVSDVVAMNAEPRYATIAVGIPAKISVEMMEAFYRGVRRACEKYGLVLVG 132

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNL 186
           GDT      A   L I+   +G          +    GD+L VSG LG   A    +L  
Sbjct: 133 GDTT-----AAHTLCISVTVVGEARMEDVIFRRGARPGDLLCVSGDLGAAYAGLKILLEQ 187

Query: 187 REQLGLDG-ELVSDCAVLTPLIQT-LRDIPGVKALRDATR------------GGVNAVVH 232
           R  L   G +   D      +IQ  L     +  +RD                G+ + VH
Sbjct: 188 RRALKEKGADYQPDLEPYRYVIQRQLLPEARLDVIRDWRDRGVRPRALIDVSDGLASEVH 247

Query: 233 EFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVL 288
                  CG  +  +A+PV    R V +    D    AL    + +L+ A+        L
Sbjct: 248 HLCRHSNCGAIVYASAIPVALETREVADHFAEDVDTYALFGGEDYELLFALPPEQ----L 303

Query: 289 AALHSHPLGKDAALIGEVVE-RKGVRLAGLYGVKRTLDL 326
             L          +IGE +   +GV++    G    L+ 
Sbjct: 304 ELLDPTSFN----VIGEFLPADQGVQVQTPEGAIIPLEP 338


>UniRef50_C4ZI96 Hydrogenase expression/formation protein n=1 Tax=Eubacterium
           rectale ATCC 33656 RepID=C4ZI96_EUBR3
          Length = 333

 Score =  167 bits (423), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 52/269 (19%), Positives = 107/269 (39%), Gaps = 16/269 (5%)

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVV 135
           A+    N++   GA P  +    ++        L+  V ++      AGI ++ G T+V 
Sbjct: 70  AVYDALNNIYAMGADPVGIELALLVPTTENEAVLRETVRAIDAVCEKAGIVVLGGHTQVS 129

Query: 136 QRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE 195
           +  AV  + +    +G         +     G  ++V+G +G  G  IL   ++  L+  
Sbjct: 130 R--AVKNIVVTVTAIGEAYEQALTPSSAAAPGMDVIVTGYVGLEGTAILANEKRTELETR 187

Query: 196 L----VSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
                +   A     I T  +       GV A+ DA++GG+   + + A A G G+++  
Sbjct: 188 FSKAFIDKSAAYIDHISTAMEAASAIGAGVAAIHDASQGGIFGALWDMAEASGIGLDIDL 247

Query: 247 AALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
             LP++     + E   ++     + G L+I        +V+  L     G++A ++G  
Sbjct: 248 KKLPIRQDTIEISEFFDINPYKLLSGGSLIIIAA--DGTRVVRELEKT--GQNAVIVGAT 303

Query: 307 VERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
            +     L      +R L+    + + ++
Sbjct: 304 TDSNDRVLISGE-ERRFLETAQTDEIYKV 331


>UniRef50_Q46DN9 Thiamin-monophosphate kinase n=4 Tax=Methanosarcinaceae
           RepID=Q46DN9_METBF
          Length = 340

 Score =  167 bits (423), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 68/327 (20%), Positives = 121/327 (37%), Gaps = 31/327 (9%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARL------DLAQLVAEG-DRLAFSTDSYVID---PL 65
           + LI S+  E F  P   E+E +  L      D A L  +G D L  +TD        P 
Sbjct: 12  RALI-SILSEIFKAPDGREKEQEGILIGAGSDDCAVLDLKGEDCLVVTTDMLHRTTDFPE 70

Query: 66  FFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGI 125
                 IG ++     +D+A  GA P  L     +     +  ++A+   M       G 
Sbjct: 71  EMTPWQIGWMSAAVNLSDIAAMGAEPTGLVMAIGMPADTEIAFVEALAKGMQACTEFCGT 130

Query: 126 AIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN 185
            I+ GD          +L I    +G +  +     +    GD++ V+G  G  GA +  
Sbjct: 131 MIIGGD-----LDTHTELTITGTALGRVKKSQLLLRRGARPGDLVCVTGYTGSAGAALEA 185

Query: 186 LREQLGLDGELVSDCA---VLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           L+    +   ++         T   + L +   V ++ D T  G+   +++ +     G 
Sbjct: 186 LQSGKPVSETVLKALFEPVPRTKEARKLAESGAVTSMMD-TSDGLAMSLYDLSRQSRVGF 244

Query: 243 ELSEAALPVKPAVRGVCE---LLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            + E ALPV   VR        L   +L    + +L+I ++    ++V           +
Sbjct: 245 MIRENALPVLREVRKFASNPNRLREFSLYTGGDFELLITIDPQKIKKVQNIC-------N 297

Query: 300 AALIGEVVE-RKGVRLAGLYGVKRTLD 325
             +IGE  +   G+ L        T++
Sbjct: 298 LVVIGECTKYEAGIVLESPECEHITIE 324


>UniRef50_C4LAD9 Thiamine-monophosphate kinase n=1 Tax=Tolumonas auensis DSM 9187
           RepID=C4LAD9_TOLAT
          Length = 328

 Score =  167 bits (423), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 69/308 (22%), Positives = 112/308 (36%), Gaps = 21/308 (6%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFPGGN---I 72
           +LI   F         A+ E     D A L V  G+ LA STD+ V D  FF   +   +
Sbjct: 5   ELIQHYFAA--QAAARADVELGIGDDCALLNVPVGECLAVSTDTLVSDVHFFADVDPVAL 62

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA PR++S    L +   +  L          A    +A++ GDT
Sbjct: 63  GHKALAVNLSDLAAMGAQPRWISLALTLPKADDV-WLTGFTQGFHALAVKHNVALIGGDT 121

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I  +  G +PA          AGD + VSG+LG     +      L +
Sbjct: 122 TRGP------LSITISAKGTVPAAQALRRSGAKAGDAIYVSGSLGAAALAVQQRIHNLPI 175

Query: 193 DGELVSDCA----VLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
           + + + DC+       P  +    + G+         G++  +     A G   E+    
Sbjct: 176 NSDALRDCSFRMDYPQPRCELGLALRGIATSALDLSDGLSGDLMHILRASGVAAEIELTN 235

Query: 249 LPVKPAVRG--VCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           LP+  AV+     E     AL   ++ +L   V       +     +  L      IG +
Sbjct: 236 LPIASAVQRSVTPEQALQLALGGGDDYELCFTVPAGHETAISEL--AVALDLPLTRIGTI 293

Query: 307 VERKGVRL 314
              +   +
Sbjct: 294 TTGEPQII 301


>UniRef50_C6LD50 Hydrogenase maturation factor n=1 Tax=Bryantella formatexigens DSM
           14469 RepID=C6LD50_9FIRM
          Length = 362

 Score =  166 bits (422), Expect = 8e-40,   Method: Composition-based stats.
 Identities = 70/365 (19%), Positives = 125/365 (34%), Gaps = 52/365 (14%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+  + ++    ++   N   A  +         L+   ++ A    S  + P       
Sbjct: 4   GKIPEAVLKRSVLKQCQNTHPAVLQGAGSGSDCALILTAEKSAV---SCSVHPAVLDTMK 60

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
             + AI    N++A +G+ P  +    +L E      LK V+       +  GI I  G 
Sbjct: 61  KVRFAIEHAVNNLACAGSEPEAVLLTVLLPENTEEAFLKEVMREAEAVCKELGIQIAGGH 120

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANI---------------------------------H 158
           T+V    AV    +    +GA P+                                   +
Sbjct: 121 TEVNP--AVMLPLLTVTALGAAPSGATTSKAIAPRATPSGEAASGAATSGVHGAGAMDSY 178

Query: 159 WGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSD----CAVLTPLIQTLRDIP 214
             A     G  +L++GT+   G  +L    +  L     +D           I  L+   
Sbjct: 179 LRAAGAQPGMDVLIAGTVAREGTALLAWAHEEELKKRFPADFVEQAESFGSSISILQAAR 238

Query: 215 -----GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNF 269
                G  AL DA++GG+   + E     GCG+      +P++     +CE  G +    
Sbjct: 239 VAMQCGAAALHDASQGGIFGALWELCEGAGCGLTADLRKIPIRQETIEICEYFGYNPYCL 298

Query: 270 ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHA 329
            + G L++        +V   L  H  G  AA+IG++ +     L      +R LD P  
Sbjct: 299 LSGGALLVVAP--DGRRVEMELARH--GITAAVIGKLTDSNDRILLNGE-ERRFLDRPAQ 353

Query: 330 EPLPR 334
           + + +
Sbjct: 354 DEIWK 358


>UniRef50_A0M637 Thiamine-monophosphate kinase n=43 Tax=Bacteroidetes
           RepID=A0M637_GRAFK
          Length = 351

 Score =  166 bits (420), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 67/333 (20%), Positives = 120/333 (36%), Gaps = 40/333 (12%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTD----SYVIDPLFFPGGNIG 73
           LI+ L      +P L         D A L  +  +   STD        D  + P  ++G
Sbjct: 20  LIDHLTKNF--SPKLESTIKAIGDDAAVLNFKNKQTLISTDLLVEGVHFDLAYMPLKHLG 77

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A+    +D+         ++  F      P+E L+ +   +   A+   + ++ GDT 
Sbjct: 78  YKAVMVNLSDIYAMNGTATQITVSFAASNRFPVEALEELYAGIQLAAKLYNVDVIGGDTT 137

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL- 192
               G    L I+   +G              A D+L++SG LG     +  L  +  + 
Sbjct: 138 SSTSG----LMISVTAIGIAEKEEITYRNGAKANDLLVLSGDLGAAYMGLQVLEREKQVF 193

Query: 193 --DGELVSDCAVLTPLIQTLR------DIPGV--------KALRDATRGGVNAVVHEFAA 236
             +     D    T LI+         DIP +         ++ D +  G+++ V     
Sbjct: 194 KANPNSQPDLDQYTYLIERQLKPEARQDIPPLLKELEVQPTSMIDISD-GLSSEVIHLCK 252

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALH 292
               G  L E  +P+ PAV  VCE   +D    AL+   + +L+  + ++  +++     
Sbjct: 253 NSKLGANLFEEKIPLDPAVISVCEEFEIDSTMVALSGGEDYELLFTISQDDYDKI----- 307

Query: 293 SHPLGKDAALIGEVVERK-GVRLAGLYGVKRTL 324
                    +IG + E   G+ L      K  L
Sbjct: 308 --KGNPHLTVIGHMTEENEGMHLVTRANQKLPL 338


>UniRef50_B5FBG0 Thiamine-monophosphate kinase n=7 Tax=Vibrionaceae
           RepID=B5FBG0_VIBFM
          Length = 332

 Score =  165 bits (417), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 67/310 (21%), Positives = 120/310 (38%), Gaps = 32/310 (10%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLA-QLVAEGDRLAFSTDSYVIDPLFFPGGN---IG 73
           LI+  F++   N    + +     D A   V EG ++A +TD+      F    +   +G
Sbjct: 7   LIDRFFVQ--ENVSRDDVDLGIGDDCALVTVPEGYQVAITTDTLAAGTHFLADADPVSVG 64

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A+    +D+A  GA P ++S    L +    + L+       + A+   + ++ GDT 
Sbjct: 65  HKALASNLSDLAAMGAKPTWVSLALTLPQS-DEKWLEGFCRGFFDLAKQYQVELIGGDTT 123

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA---TILNLREQL 190
                    L I     G IP            GD + V+G LGD  A    ILN  + +
Sbjct: 124 KGP------LSITITVQGIIPKGSALTRSAAQIGDDIYVTGNLGDSAAGLEVILNSHKNV 177

Query: 191 --GLDGELVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSEA 247
              L+ EL       TP ++  +DI  +  A  D +  GV + +            ++  
Sbjct: 178 KGELEKELEKRHYYSTPQVELAQDIRHLCHAALDISD-GVISDLGHILKQSNVSAVINVN 236

Query: 248 ALPVKPAV-------RGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
            LP+   +       +  C+ L   AL    E +L     +   + +     +  L K  
Sbjct: 237 NLPISSELVTYYRQDKEKCQKL---ALTSGEEYELCFTASKKNRKAIKQI--ATILNKKI 291

Query: 301 ALIGEVVERK 310
           ++IGE++++ 
Sbjct: 292 SIIGEIIDKP 301


>UniRef50_Q2RJB8 Thiamine-monophosphate kinase n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RJB8_MOOTA
          Length = 337

 Score =  165 bits (417), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 78/325 (24%), Positives = 119/325 (36%), Gaps = 24/325 (7%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAF-STDSYVIDPLF----FPGGNI 72
           LI  L   A  +P  A        D A L  E   L   STD  V D  F         I
Sbjct: 11  LIERLKAGAIVDP--ARVVMGIGDDAAVLKGEPGFLTLASTDMLVEDIHFTLATATPREI 68

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G   +    +D+A  G IP        L     +E +  +   + E  +  G+ I+ GDT
Sbjct: 69  GYKTMAVNVSDIAAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFGVNIIGGDT 128

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
               R     + IN A +G +  +          GD+LLV+G LG   A +  L      
Sbjct: 129 VSSPRA----MVINLAILGRVENDACLYRHGAQPGDILLVTGDLGGSAAGLDTLLSPRPA 184

Query: 193 DGELVSDCA-------VLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
             E+++               I+      G+ A  D + G V   V+  A A   GI L 
Sbjct: 185 PAEVIAWARARHFRPTPRVVEIRAALKAGGLTAADDISDGLVA-EVYTLATASRVGIVLE 243

Query: 246 EAALPVKPAVRGVCELLGLDALNFANEG----KLVIAVERNAAEQVLAALHSHPLGKDAA 301
             A+P+ PA R +  +   + L++A  G    +L++A   +  + V  A++         
Sbjct: 244 AGAIPIAPATRQLAAIYHKEPLDYALYGGEDFELLLACRPDKVDAVREAVNRACR-TPVT 302

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDL 326
           +IG VV  +        G    L  
Sbjct: 303 VIGRVVPAEEGITINHSGRVLPLTP 327


>UniRef50_C6X363 Thiamine-monophosphate kinase n=6 Tax=Bacteroidetes
           RepID=C6X363_FLAB3
          Length = 364

 Score =  164 bits (416), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 69/335 (20%), Positives = 123/335 (36%), Gaps = 41/335 (12%)

Query: 18  LINSLFMEA-FANPWLAEQEDQARLDLAQLVAEGDRLAFSTD----SYVIDPLFFPGGNI 72
           LI  L  +  F NP     E     D A +  +  ++  +TD        +  + P  ++
Sbjct: 34  LIKHLTEKFGFDNP---STETSIGDDAAVIDPQNQKVVITTDILAEGVHFNLGYVPLKHL 90

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A   AIP  +  G  +    P+E L+ +   +A   +   + +V GDT
Sbjct: 91  GYKAVVVNLSDLAAMNAIPTQILVGLAVSNRFPVEALEEIYEGIALACKRYKVDLVGGDT 150

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH--GATILNLR--- 187
                G    L +    +G   +            D+L+V+G LG    G  IL      
Sbjct: 151 TSSTSG----LVMGITAIGLEQSENLIKRSGAKPNDLLVVTGDLGGAYLGLQILEREHSV 206

Query: 188 ---------EQLGLDGELVSDCAV--LTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFA 235
                    E  G D  L         T + +TL+++     ++ D +  G+++ +   A
Sbjct: 207 YLANPNMQPEMEGYDYILERQLKPEARTDIKKTLKELDIQPTSMIDVSD-GLSSEILHLA 265

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAAL 291
                G  L E  +P+        E L L+     +N   + +L+  +     E++    
Sbjct: 266 DQSKVGFRLYEEKIPMDSLTISTAEELNLNPVMCAMNGGEDFELLFTIAPEDFEKI---- 321

Query: 292 HSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDL 326
            +HP   D ++IG  VE          G    + L
Sbjct: 322 RNHP---DFSIIGHAVEADEGNFLVARGSNELIAL 353


>UniRef50_A0L3Z7 Thiamine-monophosphate kinase n=1 Tax=Magnetococcus sp. MC-1
           RepID=A0L3Z7_MAGSM
          Length = 338

 Score =  163 bits (414), Expect = 7e-39,   Method: Composition-based stats.
 Identities = 76/321 (23%), Positives = 119/321 (37%), Gaps = 37/321 (11%)

Query: 19  INSLFME----AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN--- 71
           I  +F            L   +D A L    +V     L  +TD+ V    F    +   
Sbjct: 15  IQHIFAPIQSKQGEGVQLGIGDDAACL----VVPRTQDLLATTDTMVEGIHFSSDADPYL 70

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G+ A+    +D+A  G +PR+      +        L+     +   +    +A+V GD
Sbjct: 71  LGQKALAVNLSDIAAMGGLPRWYLLSMAVPNRTSQSWLEEFARGVKAASEMFHVALVGGD 130

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T         K+ I    +G I  +          GD L +SGTLGD    + +L  +L 
Sbjct: 131 TVRSNA----KIVITVQMLGLIGQHRAVARSGAQVGDRLYLSGTLGDSAFGLAHLLGKL- 185

Query: 192 LDGELVSDCAVLT-------PLIQ---TLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
               L  D + L+       P IQ    L+D     A  D + G +   +     A    
Sbjct: 186 -PAMLADDVSYLSRRHHLPEPRIQLGMALQDAALAHACIDVSDGLLAD-LQHICEASQVS 243

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFA----NEGKLVIAVERNAAEQVLAALHSHPLG 297
             +    LP   + + V    G  AL  A     + +L+ A+   AA+QV   +  H +G
Sbjct: 244 AVVDVEKLPFSESAQRVIAQYGRSALELALTGGEDYELLFAISPGAADQVEKIV--HQVG 301

Query: 298 KDAALIGEVV---ERKGVRLA 315
                IGEVV   ER GV + 
Sbjct: 302 VSLVEIGEVVGVGERPGVVVR 322


>UniRef50_B6YTL7 Thiamine monophosphate kinase n=2 Tax=Thermococcus
           RepID=B6YTL7_THEON
          Length = 311

 Score =  163 bits (413), Expect = 8e-39,   Method: Composition-based stats.
 Identities = 72/327 (22%), Positives = 116/327 (35%), Gaps = 35/327 (10%)

Query: 15  MQQLINSLFMEAFANPW---LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           M++ I  LFM+         L +     R+    LVA  D L   TD     P       
Sbjct: 1   MEREIIELFMKYLKKQGDLPLGDDAGALRIGDEWLVATNDMLVGKTD----VPDIMTPEQ 56

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  A+    +D+A  GA P        +  G     L+ V   +        I +++ D
Sbjct: 57  VGFKAVTMNVSDIAAMGARPIGFLFSLGVPRGFDGLYLEGVAKGIGNALEFYEIPVLSAD 116

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T        D L I+   +G               GD++ ++G +G   A +L  +  L 
Sbjct: 117 T-----NEADDLIIDGIALGRTRH--LLTRSGAKPGDLVCITGDIGRPLAGLLVWKNDLD 169

Query: 192 LD---GELVSD--CAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
           +     E++ +        + + ++      A  D +  G+   +H  A   G  IE+  
Sbjct: 170 VSLSTKEILYEKLLEPRARVKEGIKIGNYANAAIDISD-GLAKELHLVAEMSGVRIEVDA 228

Query: 247 AALPVKPAVRGVCELLGLDALNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           + LP+   V  V ELL  D L  A     E +LV  +     E+         L  D  +
Sbjct: 229 SKLPIMEEVFEVAELLRRDPLEIALASGEEFELVFTIPPKYTEE---------LSFDFTV 279

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHA 329
           IG V +  GV +      KR    P  
Sbjct: 280 IGTVHKGAGVFITTE--EKRMEVPPIG 304


>UniRef50_Q57190 Thiamine-monophosphate kinase n=279 Tax=Gammaproteobacteria
           RepID=THIL_HAEIN
          Length = 328

 Score =  163 bits (413), Expect = 8e-39,   Method: Composition-based stats.
 Identities = 67/306 (21%), Positives = 116/306 (37%), Gaps = 27/306 (8%)

Query: 21  SLFMEAFANPWLAEQEDQARL--DLA-QLVAEGDRLAFSTDSYVIDPLFFP---GGNIGK 74
            L    F    L +   Q  +  D A   V E  +LA +TD+ V +  F P     ++  
Sbjct: 7   DLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPEDLAY 66

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
            A+    +D+A  GA P+++S    L   +    +     S+  T +   + ++ GDT  
Sbjct: 67  KAVATNLSDLAAMGAQPKWVSLALTLP-NVDENWISTFSQSLLHTLKQYNVTLIGGDT-- 123

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNLREQLG 191
             +G    L I     G +  N          GD++ VS TLGD  A    IL  +  + 
Sbjct: 124 -TKGN---LSITITAQGFVEKNKGICRHKAQIGDLIYVSSTLGDSAAGLTQILLGKSAVD 179

Query: 192 LDG-ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
            D   L       TP I+  + + G+  +      G+ + +        C  E+   ALP
Sbjct: 180 SDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHILERSQCSAEVELTALP 239

Query: 251 VKPAV-----RGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           +  ++     R   E     AL+   + +L   +     +++   L    L      IG+
Sbjct: 240 LSSSILNKYDRTQAEQF---ALSGGEDYELCFTIPPEYKDELELRLKK--LNVPCTCIGK 294

Query: 306 VVERKG 311
           + E+ G
Sbjct: 295 INEKCG 300


>UniRef50_C6VU01 Thiamine-monophosphate kinase n=25 Tax=Bacteria RepID=C6VU01_DYAFD
          Length = 340

 Score =  163 bits (413), Expect = 9e-39,   Method: Composition-based stats.
 Identities = 65/330 (19%), Positives = 119/330 (36%), Gaps = 42/330 (12%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV----IDPLFFPGGNIGK 74
           IN     A  +      +D A +DL + +        ++D ++     D  FFP  ++G 
Sbjct: 19  INKGIRPALPDTVRGIGDDAAVIDLGEELG-----LLTSDMFLEGIHFDLTFFPLKHLGY 73

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
             I    +D+A    IPR ++    L     +E +  +   M    +   + +V GDT  
Sbjct: 74  KIIAAGVSDIAAMNGIPRQVTVNLALSNRFSVEAVDELYEGMKVACKDFNVDLVGGDTTS 133

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL---- 190
            + G    L I+ +  G +  +      T    D+L V+G LG     +  L  +     
Sbjct: 134 SRSG----LIISVSAFGKVKKDKIAYRNTAQPNDLLCVTGDLGGAYMGLQLLEREKQVFL 189

Query: 191 ---GLDGELVSDCAVL---------TPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAA 237
               +  EL     V+           ++  L +   +  ++ D +  G+ + +    A 
Sbjct: 190 ANPNMQPELEGKDYVIQRQLRPEARMDVVYELDEAGVIPTSMIDLSD-GLASDLLHICAQ 248

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGL----DALNFANEGKLVIAVERNAAEQVLAALHS 293
            G G  + E  LP+          L +     ALN   + +L+  V ++A EQ+      
Sbjct: 249 SGVGAVIFEERLPIDEQTYLAASELNIGAATAALNGGEDYELLFTVSQSAYEQI------ 302

Query: 294 HPLGKDAALIGEVVERKGVRLAGLYGVKRT 323
                    IG + ++KG       G  R 
Sbjct: 303 -KNNPKITFIGYITDKKGEVELHTKGDTRV 331


>UniRef50_B0VPT8 Thiamin-monophosphate kinase n=18 Tax=Moraxellaceae
           RepID=B0VPT8_ACIBS
          Length = 305

 Score =  163 bits (412), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 61/304 (20%), Positives = 108/304 (35%), Gaps = 25/304 (8%)

Query: 17  QLINSLF-MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGGNI 72
            +I+  F  ++  +  L   +D A +          +L    D+ V     PL      I
Sbjct: 5   SIIDQYFNRQSHPDVALGIGDDSALI----TPPPNQQLVICADTLVAGRHFPLETLSHAI 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  ++    +D+A  GA P  +     L + +  E L+     + +     G+A++ GDT
Sbjct: 61  GWKSVAVNLSDIAAMGAKPHSILLAISLPQ-VDHEWLEGFSQGIYDCCNQFGVALIGGDT 119

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I    MG I             GD + VSG +GD    + +L   L  
Sbjct: 120 TQGPH-----LTITVTAMGWIETGKAVLRSGAKVGDYVCVSGQIGDAAYGLQHLGHSLQ- 173

Query: 193 DGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVK 252
                      TP  +   ++ G+ +       G+   +     A   G  L    LPV 
Sbjct: 174 -----QRLDYPTPRCKLGEELKGLASSMIDVSDGLAQDLGHILKASKVGARLILEKLPVD 228

Query: 253 PAVRGVCELLG-LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG 311
           P ++ + E      AL   ++ +L   +     E++L       L     +IG++VE+  
Sbjct: 229 PVLQQLEEQQRWQYALAGGDDYELCFTITPQNYEKLL----QKQLDVKITMIGQIVEQTK 284

Query: 312 VRLA 315
           +   
Sbjct: 285 LTFE 288


>UniRef50_D0KYD5 Thiamine-monophosphate kinase n=1 Tax=Halothiobacillus neapolitanus
           c2 RepID=D0KYD5_HALNC
          Length = 323

 Score =  161 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 69/324 (21%), Positives = 113/324 (34%), Gaps = 39/324 (12%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQARLDLAQL--VAEGDRLAFSTDSYVID---PLFFPG 69
           M +    L    F+ P           D      V EG+ L  STD  V     P     
Sbjct: 1   MNEF--ELIARYFSRPCADASVVLGVGDDCAALRVPEGEHLLVSTDLLVEGRHFPESTAA 58

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            ++G  A+    +D+A  GA P  ++ G  L   +  + L+A        A   GI +V 
Sbjct: 59  FDVGYKAMAVNLSDLAAMGARPLGVTLGLALP-SIEPDWLEAFAKGFYTLAEQHGICLVG 117

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           GDT          L +    MG+ P +         +GD++ V+GTLGD G  + +++  
Sbjct: 118 GDTVKSPV-----LSLAVTIMGSAPPDRMLTRSGAQSGDLIAVTGTLGDAGLGLRSIQRP 172

Query: 190 LGLDGELVSD--------CAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
             +   L  +            TP  +  R +  V         G+   +     A   G
Sbjct: 173 ESMPPSLNPEDIDFLQMRLNRPTPRGEEGRRLAEVAHAAIDISDGLLQDLGHILRASHVG 232

Query: 242 IELSEAALPVKPAVRGVCELLGLD------ALNFANEGKLVIAVERNAAEQVLAALHSHP 295
             +    LP+ PA R     L  D       L   ++ +L+  +  +             
Sbjct: 233 AVVEADRLPISPAARA---WLAADPTQHNLPLTAGDDYELLFTIAPDQW---------AM 280

Query: 296 LGKDAALIGEVVERKGVRLAGLYG 319
           L   A +IG + + K +R+    G
Sbjct: 281 LDVPATVIGRITQDKRLRVLDAQG 304


>UniRef50_A1AS86 Thiamine-monophosphate kinase n=9 Tax=Desulfuromonadales
           RepID=A1AS86_PELPD
          Length = 333

 Score =  161 bits (407), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 71/318 (22%), Positives = 119/318 (37%), Gaps = 25/318 (7%)

Query: 18  LINSLFMEAFANPWL--AEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---- 71
           LI+ +         +     +D A      ++  G +L  STD  + D  F    +    
Sbjct: 15  LIDRIAAHVAGGEGVITGIGDDAAV----TVLTPGMQLLTSTDMLLEDVHFRTTWHDPLA 70

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G+ ++  + +DVA  GAIPR+      +  G P+E L          A   G+ ++ GD
Sbjct: 71  LGRKSLGVSISDVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAGEHGVTLIGGD 130

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL- 190
           T   + G    L I+   M     ++        AGD + VSGTLGD    +  L +   
Sbjct: 131 TCSSKNG----LVISVTIMAEQFPHLILRRSGARAGDEIWVSGTLGDAALVLSLLEDGAV 186

Query: 191 GLDGELVS---DCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
             +  L+S   D +  T +   L +   V A+ D + G +    H  A   G G  L   
Sbjct: 187 CDEPSLLSRLLDPSPRTRVGHALAESGLVSAMIDVSDGLLADFGH-IAQQSGVGGVLYLE 245

Query: 248 ALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
            LP+    R              L+   + +L         E++ + + +   G  A  +
Sbjct: 246 RLPISADFRRRASRFPSFPHHLILSGGEDYELAFTAAAENHEKIESIVKNS--GIQATAV 303

Query: 304 GEVVERKGVRLAGLYGVK 321
           G V    GV +    G +
Sbjct: 304 GIVTSFSGVEVVMEDGSR 321


>UniRef50_B3PBC5 Thiamine-monophosphate kinase n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PBC5_CELJU
          Length = 326

 Score =  161 bits (407), Expect = 5e-38,   Method: Composition-based stats.
 Identities = 73/309 (23%), Positives = 121/309 (39%), Gaps = 23/309 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFPGGN---- 71
           QLI   F    A    A        D A L + EG +LA S D+ ++  + FP G     
Sbjct: 11  QLIQQFFQREQAEQPAAGVVLGIGDDCALLQIPEGKQLAVSVDT-LVSGVHFPEGAEPAL 69

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           I + A+    +D+A  GA P + +    L +    + L+     +   A+  GIA++ GD
Sbjct: 70  IAERALRTNLSDLAAMGAEPLWFTLALTLPQA-EEQWLREFSRGLFACAKRYGIALIGGD 128

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T          L ++   MGA+             GD +LV+ ++GD  A + +L+ ++ 
Sbjct: 129 TTAGP------LSVSIQVMGAVTPGQALRRDGANLGDFILVTHSVGDGAAALASLQGRVS 182

Query: 192 LDGE----LVSDCAVLTPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
             G+    L        P +Q   R  P   A  D + G V   +     A   G  +  
Sbjct: 183 FSGDDHAYLHERFYRPEPRLQASARIRPFASAALDISDGLVAD-LQHICTASDLGAVIDV 241

Query: 247 AALPVKPAVRGVCELLGLD--ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
            ALP+  A+    +       AL+  ++ +L   V       +  A+        A++IG
Sbjct: 242 EALPLSSALVAYPDRTQAYEWALSGGDDYELCFTVAPENMPDI--AMLIAQGQLQASVIG 299

Query: 305 EVVERKGVR 313
           E+V    V 
Sbjct: 300 EMVAGNRVI 308


>UniRef50_Q15W96 Thiamine-monophosphate kinase n=2 Tax=Alteromonadales
           RepID=Q15W96_PSEA6
          Length = 336

 Score =  160 bits (406), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 68/306 (22%), Positives = 110/306 (35%), Gaps = 32/306 (10%)

Query: 17  QLINSLFME---AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN-- 71
            LI++ F +      +  L   +D A       +  G  LA +TD+ V    F P  +  
Sbjct: 5   SLIDTYFRDVSFQRKDVLLGIGDDCAI----TQIPAGQALATTTDTLVSGVHFLPDADPK 60

Query: 72  -IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            I + AI    +D+A  GA P +LS    L   +  + LKA      E      + ++ G
Sbjct: 61  AIAQKAIAVNLSDLAAMGAEPAWLSLSLSLP-NVDEQWLKAFSEGFRELTEYYSVQLIGG 119

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I     G + A+          GD + V+G+LGD G  +  L  + 
Sbjct: 120 DTVQGP------LAITITAQGFVAADQALKRSGAKPGDFVYVTGSLGDAGLGLDILLNRA 173

Query: 191 GLDGE-----LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
            +        L+      TP +     +  V +       G+ A +     A  CG  L 
Sbjct: 174 EVKSTEHSEYLLKRLHYPTPRVFAGTSLRRVASACIDISDGLLADIKHILKASQCGACLQ 233

Query: 246 EAALPVKPAVRGVCELLGLD-----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
              LP+    + + E    D     AL+  ++ +L+  V       V   L        A
Sbjct: 234 LDKLPLS---KAMLESADRDAAFHYALSSGDDYELLFTVSEEQKNNVERVL--ACSNVPA 288

Query: 301 ALIGEV 306
             IG++
Sbjct: 289 TCIGQI 294


>UniRef50_D2RH67 Thiamine-monophosphate kinase n=1 Tax=Archaeoglobus profundus DSM
           5631 RepID=D2RH67_ARCPR
          Length = 298

 Score =  160 bits (405), Expect = 7e-38,   Method: Composition-based stats.
 Identities = 66/288 (22%), Positives = 112/288 (38%), Gaps = 31/288 (10%)

Query: 44  AQLVAEGDRLAFSTDSYVIDPLFFPG---GNIGKLAICGTANDVAVSGAIPRYLSCGFIL 100
             LV  G RLA +TD       F  G     IG LA+    +D+A  GA P +      L
Sbjct: 29  CALVDVGTRLALTTDCLHEKTDFPKGIKPEEIGHLALAINLSDLASCGAKPLFFLYTITL 88

Query: 101 EEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWG 160
            +   +E  + ++  M   A   G+A+V GDT        D+L I+   +G   A    G
Sbjct: 89  SDYW-IEYFERILKGMKNLADKYGVAVVGGDTDF-----GDELHISGFAIGK--AERFVG 140

Query: 161 AQTLTAGDVLLVSGTLGDHGATILNLREQLG-LDGELVSDCAVLTPLIQT-LRDIPGVKA 218
                 GD + V+G LG    ++  L       +           P ++  LR      +
Sbjct: 141 RDGAKVGDKICVTGLLGKAQLSLEQLMNGFSRYEIAYPDSLFKPEPRVEEGLRIAKHANS 200

Query: 219 LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD-ALNFANEGKLVI 277
           + D +   +   +H+ A   G GI++ E  +P+    + V     L+  L    + +LV 
Sbjct: 201 MTDISDS-LAISLHQIAKRSGVGIKIYEEKIPLDHLTKFVDYEKALELFLYSGGDYELVF 259

Query: 278 AVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLD 325
             +++                +   IGEV+E +GV +    G  + ++
Sbjct: 260 TSKKS----------------EYIEIGEVIEDEGVWIVRRDGRVKEVE 291


>UniRef50_B1I671 Thiamine-monophosphate kinase n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I671_DESAP
          Length = 337

 Score =  160 bits (404), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 78/325 (24%), Positives = 121/325 (37%), Gaps = 28/325 (8%)

Query: 18  LINSLFMEAFANPWL--AEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGN 71
           L+  L       P +     +D A LDL       + L F+ D+ V +  F        +
Sbjct: 11  LVERLLGRLARGPGVVRGAGDDAAVLDLG----GKELLLFTVDTLVEEVHFSRAYGSMRD 66

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  A+    +DVA  G  P Y            +  +  +   +A TA   G+ +V GD
Sbjct: 67  LGAKAMAVNLSDVAAMGGRPVYAVVSLAAPAETAVADIDDLYAGLAGTAARYGVTLVGGD 126

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T     G    L I  A +G          +   +GD+  V+G+LG   A +   +    
Sbjct: 127 TVRHPHG----LVITVALLGLAGRERVLYRKGAVSGDLFYVTGSLGASAAGLFLFQNPHP 182

Query: 192 LDGELVSD---CAVLTPLIQT----LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
                V D    A L+P  +     L    GV +  +    G+   V     A G G  L
Sbjct: 183 ACPPEVEDRLKKAHLSPEPRVVAGGLLAASGVVSAAEDISDGLALTVAHICTAGGVGARL 242

Query: 245 SEAALPVKPAVRGVCELLGLDALNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
               +P+ P VR +  L G D L +A     + +L+  V   AA  +   + +   G   
Sbjct: 243 LADRVPLSPEVRRLGILTGKDPLEWALFGGEDYELLFTVRPGAAAGLEREMAAA--GWPV 300

Query: 301 ALIGEVV-ERKGVRLAGLYGVKRTL 324
             IGEV+   +G+ L    G  R L
Sbjct: 301 TWIGEVLGPGEGLWLEDAAGAGRPL 325


>UniRef50_A8PLC8 Thiamine-monophosphate kinase n=2 Tax=Gammaproteobacteria
           RepID=A8PLC8_9COXI
          Length = 323

 Score =  159 bits (403), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 66/317 (20%), Positives = 114/317 (35%), Gaps = 26/317 (8%)

Query: 17  QLINSLF---MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GG 70
           +LI   F   M+   +  L   +D A L+    V    +L  STD++V    F       
Sbjct: 7   ELIQRFFNQPMKCRNDVTLGIGDDGAVLN----VPFNQQLVVSTDTFVAGRHFPEETLPE 62

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IG  A+    +D+A   A P ++     L   +    LK          +   + +V G
Sbjct: 63  DIGYKALAVNLSDLAAMAAEPAWILLALTLP-HVDETWLKKFNQGFFSLIQQFQLQLVGG 121

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG--ATILNLRE 188
           D   + RG    L I    +G +P            GD + V+GTLGD G    ++N   
Sbjct: 122 D---LTRG---PLSITVHALGFVPQGKALRRLGAHIGDKIYVTGTLGDAGLALALMNTPS 175

Query: 189 QLGLDG----ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
             GL       +        P ++    +  + +       G+ A +H   +A   G  +
Sbjct: 176 CCGLTQSQIFSVKQRLHRPHPRVEVGIALRDIASCAIDISDGLMADLHHLLSANQVGAIV 235

Query: 245 SEAALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
               LP+  ++RG+        AL+  ++ +L   V  +    +   L    +      I
Sbjct: 236 QLEKLPLSDSLRGLSPEKAWSLALSSGDDYELCFTVPESKERDLQQQL--ATINTPYQCI 293

Query: 304 GEVVERKGVRLAGLYGV 320
           G +    G+ L    G 
Sbjct: 294 GHIKADSGLILLDKKGA 310


>UniRef50_D2QDU8 Thiamine-monophosphate kinase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QDU8_9SPHI
          Length = 339

 Score =  159 bits (402), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 60/314 (19%), Positives = 111/314 (35%), Gaps = 39/314 (12%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYV----IDPLFFPGGNIGKLAICGTANDVAVSGAIPRY 93
               D A      D    STD  V     D  + P  ++G  AI    +D+A    +P  
Sbjct: 31  GIGDDAAVFDWGDDYGLLSTDMLVEGIHFDLTYVPLKHLGYKAITFGVSDIAAMNGLPVQ 90

Query: 94  LSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAI 153
           ++    L    P+E +  +   +     A  + +V GDT   + G    L I+ + +G +
Sbjct: 91  VTVSIALSSRFPVEAIDELYEGIRAACEAYKVDLVGGDTTASRSG----LIISVSVLGKV 146

Query: 154 PANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-------GLDGELVSDCAVL--- 203
           P N+     T    DV+ V+G LG     +  L  +         +   L  + A L   
Sbjct: 147 PKNLITYRNTAKPNDVVCVTGDLGAAYLGLQLLEREKQVFLADPNMQPNLSEERAYLVQR 206

Query: 204 -------TPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAV 255
                  T ++  LRD+     ++ D +  G+ + +       G G  + +  +P+    
Sbjct: 207 QLRPDARTDMVHELRDLGIRPTSMIDISD-GLASELLHLCHQSGTGAIIFDENIPIDDQT 265

Query: 256 RGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV-ERK 310
               +   +      LN   + +L+  V     E++               IG +  + K
Sbjct: 266 HLAADEFKISPITAALNGGEDYELLFTVPPQEFEKL-------SANARITAIGYLTADPK 318

Query: 311 GVRLAGLYGVKRTL 324
            + LA   G +  +
Sbjct: 319 QIVLATKAGQQTPI 332


>UniRef50_Q8ESJ0 Thiamine monophosphate kinase n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8ESJ0_OCEIH
          Length = 322

 Score =  158 bits (401), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 68/315 (21%), Positives = 115/315 (36%), Gaps = 28/315 (8%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNI 72
             I+S+    +  P L +       D A +      +  + D++V D  F        +I
Sbjct: 5   SFIDSIKPTYYRQPSLLKG----IGDDAAVFRSSKDIVTAVDTFVEDVHFSRSTMEPYHI 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P +     ++ +      L  + + M + A    + I+ GDT
Sbjct: 61  GYRALGANISDLAAMGASPSFYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDT 120

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH--GATIL--NLRE 188
                 +  +L I+   +G    N     Q    GD++ V+GTLGD   G  IL  +   
Sbjct: 121 V-----SGKQLTISITVIGYTITNKARYRQHAKEGDIVFVTGTLGDSLAGFHILTSDNEN 175

Query: 189 QLGLDGEL----VSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
              +D +                Q L  +  V +L D +  G+     E A A    I L
Sbjct: 176 NRYVDQDFYIHRHRKPEPRVAFAQALESLDRV-SLNDVSD-GIANEASEIAEASNVSIVL 233

Query: 245 SEAALPVKPAVRGVCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
            E  +PV P+             L+   + +L+  V +     V  A  +        +I
Sbjct: 234 RENDIPVAPSFYQFTYEQQYQWKLSGGEDFELLGTVAKGDWAVVNEA--AEKTNTQLTVI 291

Query: 304 GEVVERKG--VRLAG 316
           G VVE +   V +  
Sbjct: 292 GSVVEEEKHPVYIED 306


>UniRef50_A3DPV0 AIR synthase related protein domain protein n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DPV0_STAMF
          Length = 339

 Score =  158 bits (401), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 54/313 (17%), Positives = 115/313 (36%), Gaps = 25/313 (7%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPG---GNI 72
           +++I+    +     +L   +D        ++    R+  + D Y I  +  P     ++
Sbjct: 18  EKIISKYIHKPLPGEYLDYPDDA-----RDILPISPRILVNIDGYSISSMKLPWRTWSDV 72

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G +A+ G  +D    GA+PR +     L   +    ++ +   + E +R   + ++ GDT
Sbjct: 73  GYVAVAGAISDQIAKGAVPRDIMVSLGLPPSMEASIVEEIYKGIDEASRDYNLRLLGGDT 132

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                      +I+ A +G   A      +    GD+++V+   G  G   +N  E    
Sbjct: 133 NSSST-----PWISVAVIGYTTAKKPPSRKNAKPGDIVVVTSLYGAMGYVAINGVENAIH 187

Query: 193 DGELVSDCAVLTPLIQT----LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
              +V       P ++T      +  GV A  D +  G+   + E +      I L +  
Sbjct: 188 KEWVVEATKRPRPFLETAIVIASNYRGVHASIDVSD-GLGYALKELSKRSNVRIILEDKP 246

Query: 249 LPVKPAVRGVC----ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           L     +  +C      L    LN   E  +++ ++   ++ ++  +          +IG
Sbjct: 247 L-YYKELEEICNGNTRCLWKYVLNGGEEYGVILTIDPRLSDMIIDYMKKFR--IPHKIIG 303

Query: 305 EVVERKGVRLAGL 317
            V +  G+     
Sbjct: 304 RVEQGHGLVFEKE 316


>UniRef50_Q0K6Z2 Thiamine monophosphate kinase n=114 Tax=Proteobacteria
           RepID=Q0K6Z2_RALEH
          Length = 381

 Score =  157 bits (397), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 71/324 (21%), Positives = 111/324 (34%), Gaps = 22/324 (6%)

Query: 5   QLAHGSGGQAMQ-QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
            ++H       +  LI   F        L   +D A ++       G  LA STD  V  
Sbjct: 55  TMSHAQPAPLSEFDLIRRFFTRPVRKAALGVGDDCALIEGRP----GHHLAISTDMLVSG 110

Query: 64  PLFFP---GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
             FFP     ++G  A+    +D+A  GA PR  +    L E  P   L  +   M   A
Sbjct: 111 RHFFPDVAPRSLGHKALAVNLSDLAAMGAEPRAFTLALALPEADP-AWLAELADGMLALA 169

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
            A G  +V GDT          L ++    G +P            GD + +SGTLGD  
Sbjct: 170 DAHGCELVGGDTTRGP------LTLSLTVFGDVPLRAALRRDAARPGDDIWISGTLGDAR 223

Query: 181 ATILNLREQLGLDGELVSDCAVL----TPLIQTLRDIPGVKALRDATRGGVNAVVHEFAA 236
             + + R +  L     S         TP +     + GV         G+   +     
Sbjct: 224 LALGDCRGEWLLPEPEFSQVRPRMDTPTPRVALGMALRGVAHAALDISDGLVGDLGHILE 283

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHP 295
               G  +   ALP    +    + +  +  L   ++ +L       + + + A   S  
Sbjct: 284 RSQVGALVDVDALPRSAVLASQPDAIQRECVLAGGDDYELCFTAPAGSRDAIAAI--SER 341

Query: 296 LGKDAALIGEVVERKGVRLAGLYG 319
           L    A +G +    G+RL    G
Sbjct: 342 LALPLARVGAITPEPGLRLVDSTG 365


>UniRef50_C9RLV8 Thiamine-monophosphate kinase n=1 Tax=Fibrobacter succinogenes
           subsp. succinogenes S85 RepID=C9RLV8_FIBSS
          Length = 328

 Score =  156 bits (395), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 66/260 (25%), Positives = 103/260 (39%), Gaps = 28/260 (10%)

Query: 80  TANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGA 139
             +DV+  G  P+    G  + +    ET   +  ++A+     GI ++ GDT     G 
Sbjct: 76  NVSDVSSMGGRPKIALFGLCVNKNWSEETRNRIAKAVAQGFERRGITLIGGDTVSGDVG- 134

Query: 140 VDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI---LNLREQLGLDGEL 196
                 +T  +G     I         GD + V+GTLG   A +   +N  E+      L
Sbjct: 135 ----MFSTTLLGTTDGEISLLRSDAKPGDHVFVAGTLGKSDAGLWILMNHPEEANRFPRL 190

Query: 197 VSDCAVLTPLIQTLRDIPGVKALRDATRG-------GVNAVVHEFAAACGCGIELSEAAL 249
           V        L   + +  G + ++   RG       G+++  +  A + G  IE+ E  L
Sbjct: 191 VE-----YHLAPKICEDAGAQLVKQGVRGACMDISDGLSSETNHLALSSGVSIEIDEQKL 245

Query: 250 PVKPAVRGVCELLGLDALNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           P+ P V  +CE  GL  L FA     E +L+     N  + +   L   P   +   IG 
Sbjct: 246 PIDPDVLEMCEYFGLSPLQFALNGGEEYELLFT--SNLTKSIY--LEGAPKMGEIHDIGL 301

Query: 306 VVERKGVRLAGLYGVKRTLD 325
           V    GV L G  GVK  L+
Sbjct: 302 VSCGNGVYLKGQDGVKALLN 321


>UniRef50_Q3AE31 Thiamine-monophosphate kinase n=1 Tax=Carboxydothermus
           hydrogenoformans Z-2901 RepID=Q3AE31_CARHZ
          Length = 326

 Score =  155 bits (393), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 64/298 (21%), Positives = 111/298 (37%), Gaps = 25/298 (8%)

Query: 40  RLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVSGAIPRYLS 95
             D A +V    +L  +TD  V +  F         +GK A+    +D+A  G IPR+  
Sbjct: 29  IGDDAAVVEIKGKLLVTTDLLVENVHFKRNYTKPEILGKKALAVNLSDIAAMGGIPRFCL 88

Query: 96  CGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
               L +   +  ++     +   A+  G+ ++ GDT     GA  ++ +    +G    
Sbjct: 89  VSLALPKTTEVNFVEGFYQGLKSMAKEYGVTLIGGDTT----GAGSEIMVAVTVLGEALE 144

Query: 156 NIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ------LGLDGELVS---DCAVLTPL 206
                      GD + VSG LGD  A +  L ++        ++  L+S   +      L
Sbjct: 145 EGVLTRSGAKPGDGVYVSGYLGDSAAGLYLLLKEKLGLLPEEVEKYLISRHLEPEPRLEL 204

Query: 207 IQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
            Q L       +  D +  G+   + E A A G  I ++   +P+  A+   C+   L  
Sbjct: 205 GQLLCREKFATSTNDLSD-GLVKKLQEIARASGVEITINREKIPLSFALLTFCQQFTLKP 263

Query: 267 LNFA----NEGKLVIAVERNAAEQVLAA---LHSHPLGKDAALIGEVVERKGVRLAGL 317
           L+FA     + +L+  V     E++      L    +       G V    GV L   
Sbjct: 264 LDFALHGGEDYELLFTVPAEKEEELFKLDLPLFKIGMVTGYDERGRVKAEDGVVLQDR 321


>UniRef50_O05514 Thiamine-monophosphate kinase n=5 Tax=Bacillus RepID=THIL_BACSU
          Length = 325

 Score =  155 bits (393), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 63/296 (21%), Positives = 105/296 (35%), Gaps = 22/296 (7%)

Query: 36  EDQARLDLAQLVAE-GDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVSGAI 90
           +     D A   A+ G +     D+ V D  F        +IG  A+    +D+A  G I
Sbjct: 21  DVGIGDDAALYTAKHGVQEIVCVDTMVEDVHFKLHYSSPEDIGYKALAVNISDIAAMGGI 80

Query: 91  PRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGM 150
           P++      +        +KA+   M E A+   + ++ GDT        DKL +    +
Sbjct: 81  PKFYLVSLAVPSKWTESEIKAMYEGMNELAKLYHMDLIGGDTVST----ADKLVVTVTVI 136

Query: 151 GAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTP----- 205
           G I              D++ V+G +G   A +  L E+       V     +       
Sbjct: 137 GEIEKGQACLRSLAKPNDIVFVTGEIGSSAAGLSLLLEETNPQNSSVETDYFIHRHKRPE 196

Query: 206 ---LIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELL 262
               +  L  I    AL D +  G+ + ++E A A    IE+ E+ LP+   +  +    
Sbjct: 197 PRVSVGRLCSIFKRAALNDVSD-GLASELNEIAEASCVSIEIVESMLPIHSDLPKLHPNW 255

Query: 263 GLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE--RKGVRLAG 316
              AL    + +L   V     E +     +  L      IG V E  +  V L  
Sbjct: 256 KEWALFGGEDFELTGTVSNEEWEVLKQECAA--LHLPITKIGYVREKTKSKVILKT 309


>UniRef50_Q6AKX6 Related to thiamine-monophosphate kinase (ThiL) n=1
           Tax=Desulfotalea psychrophila RepID=Q6AKX6_DESPS
          Length = 328

 Score =  155 bits (392), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 62/301 (20%), Positives = 102/301 (33%), Gaps = 28/301 (9%)

Query: 38  QARLDLAQLVAEGDR-LAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPR 92
               D A    +  R    +TD+ V    F     P   +G  A+    +D+A  G +P 
Sbjct: 24  GIGDDCAVFSGDNGRPWLITTDTLVEGHHFDLSWHPAYELGCKAMAVNISDIAAMGGLPV 83

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
           + +      +      L   +  +A       I ++ GDT      A ++L I    +G 
Sbjct: 84  HATISLTFTKDTEEAWLDEFIRGLAYMHHRYNINLIGGDTV-----AGERLSITVTLLGQ 138

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVL--------- 203
                         GD++ V G LG   A +   +        L  + A L         
Sbjct: 139 AHKE-PVYRHGAMPGDIIYVGGPLGSAAAGLFLFQNHRDEIETLKDEYASLLRHHLAPMP 197

Query: 204 -TPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELL 262
              L + L D   + A++D +  G+   +   A        + E  +PV P    +C+  
Sbjct: 198 QVELGRALADSDYIGAMQDISD-GLATDLAHIAKKSAVQAVVFEDKIPVLPEFTRLCKRY 256

Query: 263 GL----DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLY 318
            L     AL   ++  L+  V     ++V     S      A  IG + E  GV L G  
Sbjct: 257 QLTATELALGGGDDYLLLFTVRAGREKEVERLARSVQAM--AYPIGLITEGSGVMLKGPT 314

Query: 319 G 319
           G
Sbjct: 315 G 315


>UniRef50_A7BRC9 Thiamine-monophosphate kinase n=1 Tax=Beggiatoa sp. PS
           RepID=A7BRC9_9GAMM
          Length = 351

 Score =  153 bits (388), Expect = 6e-36,   Method: Composition-based stats.
 Identities = 65/343 (18%), Positives = 119/343 (34%), Gaps = 61/343 (17%)

Query: 17  QLINSLFMEAFA---NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGG 70
            +I   F + F    +  L   +D A   +   +    +LA S D+ V     P+     
Sbjct: 5   DVIAHYFSQNFPKRTDVILGIGDDAALCSVPNYM----QLAVSIDTLVEGVHFPVTTSPE 60

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IG  A+    +D+A  GA P +++      + +    LK     + E A++A ++++ G
Sbjct: 61  DIGYKALAVNLSDMAAMGATPAWMTLALTCPK-VNETWLKRFSQGLLELAQSAQVSLIGG 119

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I     G +P            GD + V+GTLGD G  +  ++E  
Sbjct: 120 DTTQGP------LTITLQISGFVPIGQALRRDGAQPGDGIYVTGTLGDAGLGLALIQETE 173

Query: 191 GLDGELVS--DCAVLTPLIQTL------------------------------------RD 212
            +  +      C   +P+++ L                                    + 
Sbjct: 174 KIFPKEREAPRCDPPSPVVERLVSLSNHIETWEGVRGRAASKFVKSRLNRPTPCLKIGQA 233

Query: 213 IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGL--DALNFA 270
           + G+ +       G+ A +     A   G  L    LP+   +     L      AL+  
Sbjct: 234 LRGIASSAIDISDGLVADLGHILKASSVGATLQLENLPLSNVLHDYLSLEQAWYFALSAG 293

Query: 271 NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           ++ +L   V  N  + +  AL +         IG +    G+R
Sbjct: 294 DDYELCFTVPPNKEKALQEALETETY----TRIGSIETESGLR 332


>UniRef50_C8S8T5 Thiamine-monophosphate kinase n=1 Tax=Ferroglobus placidus DSM
           10642 RepID=C8S8T5_FERPL
          Length = 301

 Score =  153 bits (386), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 57/285 (20%), Positives = 108/285 (37%), Gaps = 27/285 (9%)

Query: 42  DLAQLVAEGDRLAFSTD--SYVID-PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGF 98
           D          +  + D  S   D P       IG  A+  + +D+A  GA P Y S   
Sbjct: 19  DAGFFKFGDAYIVIANDMLSRSFDFPSKLLPKQIGWKAVTASVSDLAAMGAKPIYFSYSL 78

Query: 99  ILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH 158
            L     +  ++ ++  + E     G+  ++GDT       +D + +  A          
Sbjct: 79  GLSRE-EISFVEDLMKGIREALDFYGMKFLSGDTNESTELVLDSVAVGIA-------RNL 130

Query: 159 WGAQTLTAGDVLLVSGTLGDHGATIL--NLREQLGLDGELVSDCAVLTPLIQTLRDIPGV 216
                   GD + V+G LG    ++L    + +   +  L      +  + + L+     
Sbjct: 131 LLRSNAKVGDAVCVTGDLGRAYCSLLYLLEKVEEIEEKILEKFLKPVARVDEGLKLANIA 190

Query: 217 KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA----LNFANE 272
            +  D +  G++  ++  A + G  I++ E  +P++  V   C    L+     LN   E
Sbjct: 191 NSAIDVSD-GLSKELNLLANSSGVMIKVFEDRIPIREEVLEFCTSNNLNPIEVALNSGEE 249

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGL 317
            +L+  V ++  E          L  + ++IGEV + +GV L G 
Sbjct: 250 YELLFTVSKDKLED---------LDFEFSIIGEVSKGEGVFLVGK 285


>UniRef50_C0GCU5 Thiamine-monophosphate kinase n=1 Tax=Dethiobacter alkaliphilus AHT
           1 RepID=C0GCU5_9FIRM
          Length = 335

 Score =  153 bits (386), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 70/326 (21%), Positives = 115/326 (35%), Gaps = 24/326 (7%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF-----PGG 70
           + LI     E       A        D A      +    ++   +++ + F        
Sbjct: 9   RALIKQ-ITEVLGESASANGFVGIGDDAALTTCNKEAWLVTSKDMLVEGVHFLLPAMTPA 67

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A+    +D+A  G +PR+      L +   +E +      M   A   G  I  G
Sbjct: 68  DLGYKALAVNISDIAAMGGVPRHAYVALALPKETGVEFILEFYRGMGPLAAELGTTISGG 127

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE-Q 189
           DT          L I+    G +           + GD+L  +G LG   A +  L   +
Sbjct: 128 DTVSSPG----PLMISITVQGEVDRQKALLRSGASPGDILCTTGPLGASAAGLALLLNRE 183

Query: 190 LGLDGELVSDCA-------VLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           L    +L S                  L     V A  D +  G+   + E + A GCG+
Sbjct: 184 LDCPEKLRSQALNAHFRPVPRVREADFLAHSGAVTAAMDISD-GLLEDLGEISQASGCGV 242

Query: 243 ELSEAALPVKPAVRGVCEL---LGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
            L E  +PV PA + +  L   L  +  LN   + +L++AV+      +     S   G 
Sbjct: 243 LLEEDKIPVHPAAQQIAPLAQSLAAEWALNGGEDYELLLAVQSRRFASLSREYES-RFGV 301

Query: 299 DAALIGEVVERKGVRLAGLYGVKRTL 324
               IG+VV  KG+ +    G +  L
Sbjct: 302 PLMPIGKVVGEKGLWMVTKEGKRVKL 327


>UniRef50_B8D469 AIR synthase related protein domain protein n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D469_DESK1
          Length = 340

 Score =  152 bits (385), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 72/322 (22%), Positives = 126/322 (39%), Gaps = 23/322 (7%)

Query: 9   GSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP 68
           GS G+  ++ + +L  +   +   + +      D   L+ +G RL +S D+Y I  L  P
Sbjct: 6   GSLGEMGEEAVINLIADKLISKPESGESLTYPDDARDLLPKGPRLIYSMDAYRIKSLMLP 65

Query: 69  G---GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGI 125
                +IG +A+ G  +DV V G +P     G  L     +  L+ +V  + E +    +
Sbjct: 66  WRTWSDIGWMALTGALSDVVVKGGVPSVAMIGLGLSSETDILDLEELVKGLREASNYYDV 125

Query: 126 AIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN 185
            I  GDT           +I  + MG          +    GD+++ +G+ G  G   L+
Sbjct: 126 RITGGDT-----NESLDPWIAVSVMGFTTCKRPPSRRGARPGDIVIATGSYGSMGFVALH 180

Query: 186 -LREQLGLDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            + E  G+   + +   V   L      +     + A  D +  G+   + + +   G G
Sbjct: 181 GVVEASGISWVVDNTKRVYLKLEVANVIMSTYRFIHASMDVSD-GLGYTLEQLSELSGYG 239

Query: 242 IELSEAALPVKPA-VRGVC----ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
           I L    LPV PA +R  C    E +    L    E   V+ V     ++V   L  +  
Sbjct: 240 ILLE--NLPVHPAGLREYCKNSIECMWRHVLVGGEEYGAVLIVAGEYLDKVAEELDYYE- 296

Query: 297 GKDAALIGEVVE-RKGVRLAGL 317
               ++IG V     G+ + G 
Sbjct: 297 -IPYSIIGRVGNISPGIYINGA 317


>UniRef50_A8VUM5 Beta-lactamase domain protein n=1 Tax=Bacillus selenitireducens
           MLS10 RepID=A8VUM5_9BACI
          Length = 332

 Score =  152 bits (384), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 64/298 (21%), Positives = 110/298 (36%), Gaps = 25/298 (8%)

Query: 32  LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVS 87
           L   +D A +     V +G     + D+ V D  F        +IG  A+    +D+A  
Sbjct: 23  LGIGDDAAIVR----VPDGYDQVLAVDTMVEDVHFSRATMAPEDIGYKALAVNISDLAAM 78

Query: 88  GAIPRYLSCGFILE-EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFIN 146
           GA+P+       +  +G P E  + +   + E A   G+ ++ GDT        DKL I+
Sbjct: 79  GAVPKQYLVSLAVPKQGWPDEETRRIYAGLEEAAALYGMDLIGGDTVST----ADKLVIS 134

Query: 147 TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG-------LDGELVSD 199
               G +  ++         GDV+ V+G LG   A +  L +Q            +L+  
Sbjct: 135 VTVTGIVETSVRLLRANARPGDVIAVTGPLGASLAGLDLLLDQTNGVPVPEMDQDQLIRS 194

Query: 200 CAVLTPLIQTLRDIP--GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRG 257
                P ++  R     G++A  +    G++    E A A G  + L    +P    +  
Sbjct: 195 HQRPVPQVKAGRLFAELGIRAALNDISDGISREAKEIAEASGVRMVLDWKRIPKPDILAL 254

Query: 258 VCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
             E    D  L+   E +LV          V   L +   G   + +G V   +   +
Sbjct: 255 FDEEKQKDWVLHGGEEFQLVCVFSGKHWRDVC--LLAEQHGITISPVGMVEAGEPAVI 310


>UniRef50_B7V7Q7 Thiamine monophosphate kinase n=11 Tax=Gammaproteobacteria
           RepID=B7V7Q7_PSEA8
          Length = 322

 Score =  152 bits (384), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 77/318 (24%), Positives = 119/318 (37%), Gaps = 29/318 (9%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFFPGGN---I 72
           +LI   F  A      A+       D A L    G++LA STD+ V    F  G +   +
Sbjct: 5   ELIRRFFAAAACAAPAADVALGIGDDCALLAPPAGEQLAVSTDTLVEGVHFPAGCDPFLL 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
            + A+  +A+D+A  GA P   +    L +    E L+     +   AR  G+A+V GDT
Sbjct: 65  AQRALAVSASDLAAMGAAPLAFTLALTLPQA-DAEWLQGFARGLDAMARQCGLALVGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L +     G +PA           GD+L V G LG+ GA +  + E+   
Sbjct: 124 TRGP------LSMTLTVFGRVPAGQALTRAGARPGDLLCVGGPLGEAGAALELVLERRSA 177

Query: 193 DGELVSDCAVLTPLIQT-----LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
             E+                  L       A  D + G +    H  A A G  + +   
Sbjct: 178 PAEVAEPLLARYWTPAPQFGLGLALRGKASAALDISDGLLADCGH-IARASGVALLVECQ 236

Query: 248 ALPVKPAVRGVCELLGLDALN----FANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
            L    A+ G+  L G +AL       ++  LV  +      ++ AA  +       A+I
Sbjct: 237 RLQASAALSGL--LAGEEALRQQLAAGDDYVLVFTLPPEYLGEIRAAWPAT------AVI 288

Query: 304 GEVVERKGVRLAGLYGVK 321
           G V   +GV L    G +
Sbjct: 289 GRVEAGQGVHLLDADGKE 306


>UniRef50_C4Z424 Hydrogenase expression/formation protein HypE n=1 Tax=Eubacterium
           eligens ATCC 27750 RepID=C4Z424_EUBE2
          Length = 313

 Score =  151 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 55/273 (20%), Positives = 110/273 (40%), Gaps = 21/273 (7%)

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+LA+    N+++ +  +   +    I++E      LK ++  +      AG+ I  G T
Sbjct: 51  GELAVYRAVNNISAACGVADCIMDTVIIDEKSREIRLKEIIKELDRQCCIAGVGIAGGHT 110

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA---------TI 183
            V  +  V+   ++   +G              AG  ++V+  +G  G           I
Sbjct: 111 TVSDK--VNSPVVSVMAIGHQERVQ----NKAVAGQDIVVTKHIGMSGIRTVIDCKRDEI 164

Query: 184 LNLREQLGLDGELVSDCAVLTP-LIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           L +  +  ++  L  +  +L     +         A+ D + GG+ A + + A   G GI
Sbjct: 165 LKVYSEDIINKALGDETELLVAKEAEIFMQESAYGAMHDVSEGGIFAALWDMAEYSGVGI 224

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+    +PVK  +  +CEL  ++     + G L++  +      ++  L  H  G +AA+
Sbjct: 225 EVDLRQIPVKQEIIEICELFNVNPYILDSMGCLLMTCKNGC--DIINML--HQNGIEAAV 280

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           IG++ +     +       R L LP  + + R 
Sbjct: 281 IGKITDGNNRIIHNTE-EDRYLGLPEQDEIYRF 312


>UniRef50_D1J9H7 Thiamine-monophosphate kinase n=1 Tax=uncultured archaeon
           RepID=D1J9H7_9ARCH
          Length = 335

 Score =  151 bits (383), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 55/324 (16%), Positives = 120/324 (37%), Gaps = 25/324 (7%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGGNI 72
           ++++    ++       A  +D A +D+ ++      L  +TD+       P       +
Sbjct: 13  ERIVEKFRVDREMVTVGAGDDDCAVIDIEKVRNRFKHLVITTDTLQESTHFPHGISAFQM 72

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G   +    +DVA  GA P   +    +        L  +V  + + A +   ++V GD 
Sbjct: 73  GWSIVAVNLSDVAAMGAYPFAFTIAMGIPAQTETSFLDELVAGIEKCAASYNTSVVGGD- 131

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                    +L +     G   A+          GD++ V+G+LG+    +  +R +L +
Sbjct: 132 ----ITMSKELILTGTCFG--FADRPVRRAGAKEGDLICVTGSLGNAALALKLMRGELKV 185

Query: 193 DG----ELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
            G    E+    +   P I     + +     ++ D +  G+   + E A     G+EL 
Sbjct: 186 PGDVGVEVKKALSQPVPRINEGITIANSGVATSMIDISD-GLALSLAEIAKRSSVGVELY 244

Query: 246 EAALP-----VKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           E  +P     ++  +R         A  F  + +L+  ++  A E     +         
Sbjct: 245 EDKVPVLSDEIRSDLRLSTREQRELAYYFGGDYELLFTIDAGALEN-EQVMSELIKEVKM 303

Query: 301 ALIGEVV-ERKGVRLAGLYGVKRT 323
           ++IG++V + +G+        ++ 
Sbjct: 304 SVIGKIVPQNEGIYFKNGEEKEKV 327


>UniRef50_Q1Q1A8 Similar to thiamine monophosphate kinase n=1 Tax=Candidatus
           Kuenenia stuttgartiensis RepID=Q1Q1A8_9BACT
          Length = 340

 Score =  151 bits (382), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 68/301 (22%), Positives = 106/301 (35%), Gaps = 30/301 (9%)

Query: 38  QARLDLAQLVAEGDRL-AFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPR 92
               D A +    + L   +TD  V    F         +G+ AI  + +D+A  G  P 
Sbjct: 57  GIGDDCAVINTAKNTLCLITTDMLVEGTHFDLKKHNASEVGRKAIACSISDIASMGCKPS 116

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
                     G      K +   + E A    I IV GD             IN   +G 
Sbjct: 117 VAVISLCFPHGTKNSFAKRLYAGIWEIADKYDIDIVGGD----IISGEGPFCINVTLLGK 172

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRD 212
               +        AGD +LV+G LG        L + +  +  L    A        L  
Sbjct: 173 NEGLMPVYRSGAKAGDKILVTGRLGGS-----LLGKHMFFEPRLDEGIA--------LNK 219

Query: 213 IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFA-- 270
              V A+ D +  G+ A ++      G G  L E  +PV      + +  G   ++ A  
Sbjct: 220 NFTVHAMIDISD-GLTADLNHILEESGVGAVLFEDKIPVSDDALKISKKTGKTPIHHAFS 278

Query: 271 --NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPH 328
              + +L+  + +  AE+VL        G + + IGE+VE KG+ L    G  R +  P 
Sbjct: 279 DGEDYELLAVLSKTQAEKVLT--SDLFHGLEISCIGEIVEDKGLWLRDGKGKLRRI-RPK 335

Query: 329 A 329
            
Sbjct: 336 G 336


>UniRef50_D2MI54 Thiamine-monophosphate kinase (Fragment) n=1 Tax=Candidatus
           Poribacteria sp. WGA-A3 RepID=D2MI54_9BACT
          Length = 278

 Score =  151 bits (381), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 55/252 (21%), Positives = 97/252 (38%), Gaps = 23/252 (9%)

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A     +DVA  G  P Y+     +    P + ++A+   + +      + ++ G
Sbjct: 4   DVGWRAGVANLSDVAAMGGTPLYVLVSIAVPVRTPPKNIRALYRGLQDACAPCNVELIGG 63

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          +F++   +G++ AN          GD L V+GT+GD  A +  L+   
Sbjct: 64  DTSSSPS----HVFLSLTIVGSVRANRALTRHGAEVGDRLYVTGTVGDANAGLRILQSHS 119

Query: 191 G---------LDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAAC 238
                      +  L+      TP IQ    L D     A  D +  G+++ V       
Sbjct: 120 NNLRRFSPSAAEKFLIRRHRRPTPRIQVGQLLVDRNLAHAAIDLSD-GLSSDVGHVCEES 178

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFA----NEGKLVIAVERNAAEQVLAALHSH 294
             G E+   ALP+   +R   +   LD +  A     + +L+        ++VL  L S 
Sbjct: 179 QVGAEIRGEALPLSSPLRAFAKRHDLDPMELALQGGEDYELLFIAPAKHHQKVL--LVSE 236

Query: 295 PLGKDAALIGEV 306
                 + IGE+
Sbjct: 237 QTKVPISCIGEI 248


>UniRef50_B4RQH6 Thiamine monophosphate kinase n=28 Tax=Neisseriaceae
           RepID=B4RQH6_NEIG2
          Length = 318

 Score =  151 bits (381), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 72/318 (22%), Positives = 124/318 (38%), Gaps = 24/318 (7%)

Query: 23  FMEAFANPWLAEQEDQARLDLAQLVA--EGDRLAFSTDSYVIDPLFFP---GGNIGKLAI 77
           F++ +      +       D A +V   EG  L FS D  + D  FF       +    +
Sbjct: 6   FIKRYLQTGTDKDVVLGIGDDAAIVRPREGFDLCFSADMLLKDRHFFADVKPEGLAWKVL 65

Query: 78  CGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQR 137
               +D+A  GAIPR++     L E L    L+    S    A+  G+ ++ GDT     
Sbjct: 66  AVNISDMAAMGAIPRWVLLSAALPE-LDEVWLERFCGSFFGLAKKFGVTLIGGDT----- 119

Query: 138 GAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELV 197
                +  N   +G +P           AGD + VSG +G   A +    ++  L  ++ 
Sbjct: 120 -TKGDMAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRVGMAAAALNCRLKRCVLPDDVF 178

Query: 198 SDC--AVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVK 252
           ++C   +L P  +    L  +P  +A +D +  G+   +     A G G E+   +LP  
Sbjct: 179 AECEQKLLRPEPRVGLGLALLPFARAAQDVSD-GLAQDLGHILTASGVGAEIWADSLPSL 237

Query: 253 PAVRGVCELLGLDALNFA--NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
             ++ +       +   A  ++ +LV     +   +VL A  +   G     IG++    
Sbjct: 238 SVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLDA--AERCGVPVTCIGKI--NG 293

Query: 311 GVRLAGLYGVKRTLDLPH 328
           G RL  L    R L+L  
Sbjct: 294 GCRLKVLDAGGRELELHS 311


>UniRef50_C5BS83 Thiamine-phosphate kinase n=1 Tax=Teredinibacter turnerae T7901
           RepID=C5BS83_TERTT
          Length = 315

 Score =  150 bits (380), Expect = 6e-35,   Method: Composition-based stats.
 Identities = 69/307 (22%), Positives = 110/307 (35%), Gaps = 27/307 (8%)

Query: 17  QLINSLFMEAFANPW--LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN--- 71
            LI   F  A   P   L   +D A L+    +   ++LA S D+ V D  F        
Sbjct: 7   DLIRDYFARAQDAPGVALGIGDDCALLE----IPPSEQLAVSVDTLVADVHFPADAEPYL 62

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           + + A+C + +D+A  GA PR+++    L        L      +    +A G ++V GD
Sbjct: 63  VAERALCVSLSDLAAMGAQPRWITLCLTLPA-FDEAWLAGFSAGLFSRTKAYGCSLVGGD 121

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T          L I+   MG +P       +    GD + VSG LGD  A +  +R +L 
Sbjct: 122 TTRGP------LAISVQVMGTVPVGQALRRKGAQVGDGIYVSGPLGDGAAALALVRGELE 175

Query: 192 LDGELVSDCAVLTPLIQTL----RDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
                 +         +        + G+         G+   +    ++ G    +   
Sbjct: 176 TTPSESAYLRERYFQPEPCFGWGHALRGIANAAIDVSDGLVQDLGHICSSSGVAGLVYLE 235

Query: 248 ALPVKPAVRGV-CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
            LP   AV  +        AL   ++ +L   V     +  L  L        A  IG+V
Sbjct: 236 RLPFSAAVNRLDTTARYQAALAGGDDYQLCFTVPAAR-QSALEELE-----LTAFRIGDV 289

Query: 307 VERKGVR 313
           V   GVR
Sbjct: 290 VAGSGVR 296


>UniRef50_Q5FH10 Thiamine-monophosphate kinase n=4 Tax=canis group
           RepID=Q5FH10_EHRRG
          Length = 316

 Score =  150 bits (379), Expect = 8e-35,   Method: Composition-based stats.
 Identities = 57/310 (18%), Positives = 106/310 (34%), Gaps = 14/310 (4%)

Query: 24  MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIGKLAICG 79
            E   N       +    D A ++   +     T   +I+ + F        + K A+  
Sbjct: 4   FEYLQNYIYTLDNNSLIGDDAAIINCTENQLVVTKDILIEEVHFLKNCKPRILAKKALRS 63

Query: 80  TANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGA 139
             +D+A  GAIP     G +L   +     +    S+ E  +   I ++ GDT   +   
Sbjct: 64  NLSDIAAMGAIPYAYCLGLVLPNNISNNWWQDFSNSLREEHKIFDIILLGGDTTSHKN-- 121

Query: 140 VDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE-LVS 198
            + + I+    G I             GD + VSGT+GD    +L  +  +  + E L +
Sbjct: 122 -NIIIISITAFG-INHGNLLKRSGAKIGDFIYVSGTIGDAALGLLVYQNIIKKNYENLKN 179

Query: 199 DCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGV 258
              +  P I    DI  + +       G+   +     A   G  +    +P+    + +
Sbjct: 180 KYDIPQPRINLGIDINQIASSCIDISDGLIQDMEHICHASNVGASIYLNKIPLSNETKEI 239

Query: 259 ---CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLA 315
                      L+  ++ +L+       ++ +     S   G     IG++ E   V L 
Sbjct: 240 IANTPRYINSVLSGGDDYELIFTANPKFSDSIKEI--SKKNGVKITKIGKITEGNSVILY 297

Query: 316 GLYGVKRTLD 325
                  TLD
Sbjct: 298 DHSNNIVTLD 307


>UniRef50_D1R9A7 Putative uncharacterized protein n=1 Tax=Parachlamydia
           acanthamoebae str. Hall's coccus RepID=D1R9A7_9CHLA
          Length = 333

 Score =  150 bits (379), Expect = 8e-35,   Method: Composition-based stats.
 Identities = 65/305 (21%), Positives = 119/305 (39%), Gaps = 22/305 (7%)

Query: 38  QARLDLAQLVAEGD-RLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPR 92
               D A + AE +     +TD+ +    F        ++G   I    +DVA  G  P+
Sbjct: 27  GIGDDCAVIPAENEEAWLVTTDALIEGVHFLKDQIAPIDLGYKTIAVNVSDVAAMGGTPK 86

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
           +      L   +  E  + V+  + E      I ++ GDT     G+   +FIN   +G+
Sbjct: 87  FAFLTLALPSTVHCEWTRLVLQGIKEACEKWHIQLLGGDTV----GSRRDIFINLTLIGS 142

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE---LVSDCAVLTPLIQT 209
            P            GD + VSG LG+ G  +  L+E++    E   L+      TP IQ 
Sbjct: 143 APQKHIRYRNQAQLGDRICVSGNLGNSGGGLQALKEKIQTTPEVKILLEAHFRPTPHIQQ 202

Query: 210 ---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
              L   PGV A+ D +  G++  +     +   G  +  + +P+   +  + +  G + 
Sbjct: 203 GRWLASQPGVHAMMDVSD-GLDFDLKRLIKSSHKGAHVDISKIPLSEELLKMAQTKGWNP 261

Query: 267 LNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKR 322
           L  A     +  L+I +++     +         G     IG++ ++        +G K+
Sbjct: 262 LQLALTGGEDYCLLITIDQKKQGVIQDFFKK--FGAPLYEIGQITDQVNELTYYDHGEKK 319

Query: 323 TLDLP 327
            +D P
Sbjct: 320 EIDFP 324


>UniRef50_Q2JTF1 Thiamine-monophosphate kinase n=11 Tax=Cyanobacteria
           RepID=Q2JTF1_SYNJA
          Length = 340

 Score =  150 bits (379), Expect = 8e-35,   Method: Composition-based stats.
 Identities = 59/282 (20%), Positives = 104/282 (36%), Gaps = 27/282 (9%)

Query: 42  DLAQLVAEGDRLAFSTDSYV----IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
           D A L A   +L  STD  V       +  P   +G  A+    +D+A  G+ PR L  G
Sbjct: 45  DGAVLPAPEGQLVVSTDVLVEGVHFSDVTTPAHAVGWRAVAANLSDLAAMGSRPRALVVG 104

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
             L    P+  ++ +   M       G  +V GD     +      F+    +G++    
Sbjct: 105 LGLPGSTPVAWVEELYEGMRACCARWGAELVGGDLCRSPQR-----FVAITALGSVQPGR 159

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDC----------AVLTPLI 207
               +    GD L+V+G  GD  A +  L           +                 ++
Sbjct: 160 AIERRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSATAAQRQQLIRAHQYPRPRLDVL 219

Query: 208 QTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
             L  +PG ++     T  G+   + +   + G    ++   +P+  A+R       L+ 
Sbjct: 220 SLLEALPGPLRLAGMDTSDGLADALVQVCQSSGVAARIAAERIPISVALRQAFPAQALEW 279

Query: 267 -LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
            L    + +L+++ E + A+ +L  L        AA IGEV 
Sbjct: 280 ALYGGEDFELLLSAEVSVAKHLLEKLPG------AAWIGEVT 315


>UniRef50_B4U7Q4 Thiamine-monophosphate kinase n=3 Tax=Aquificaceae
           RepID=B4U7Q4_HYDS0
          Length = 306

 Score =  150 bits (379), Expect = 8e-35,   Method: Composition-based stats.
 Identities = 58/301 (19%), Positives = 106/301 (35%), Gaps = 30/301 (9%)

Query: 35  QEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNIGKLAICGTANDVAVSGAIP 91
            E+    D A +      L  + D+++ D  F   +P   IG  AI    +DV  +G  P
Sbjct: 16  GENTIGDDTAYIKIGETGLNITCDAFLEDVHFLRHYPPEAIGFKAISINVSDVVANGGKP 75

Query: 92  RYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMG 151
            Y     ++ E +    ++ +   +        + IV G+     +  +D   I      
Sbjct: 76  LYGLISLMIPEDIDERFIERIYEGVKSACDFYKLRIVGGNVSKASKLGIDVFLIG----- 130

Query: 152 AIPANIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNLREQLGLDGELVSDCAVLTPLIQ 208
               +          GD ++VSGTLGD       +   +E    +  L+      T  I 
Sbjct: 131 --EIDRFVSRAGANVGDDVVVSGTLGDSYTGFRLLTTKKEYEDYELRLIERHLRPTARID 188

Query: 209 TLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDAL 267
            +  I     A  D +  G+++ +   A      IE+    +P+   +R       L+  
Sbjct: 189 YINHIRKYASACMDISD-GLSSDLWHIAERSNVVIEIDLNKIPISRELRLYASKENLNPY 247

Query: 268 NFANEG----KLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE-RKGVRLAGLYGVKR 322
           + A  G    +L+   ++      L             +IG V+E  K + L     ++R
Sbjct: 248 DIALSGGEDYQLLFCQKKEHFNPFLDN----------TVIGRVIEQGKALVLVNGKELER 297

Query: 323 T 323
           T
Sbjct: 298 T 298


>UniRef50_A4SVD0 Thiamine-monophosphate kinase n=1 Tax=Polynucleobacter necessarius
           subsp. asymbioticus QLW-P1DMWA-1 RepID=A4SVD0_POLSQ
          Length = 339

 Score =  150 bits (378), Expect = 8e-35,   Method: Composition-based stats.
 Identities = 57/319 (17%), Positives = 109/319 (34%), Gaps = 23/319 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLV--AEGDRLAFSTDSYVIDPLFFPGGN--- 71
            LI   F    +     E       D   L+  A    +A +TD  V    FF G +   
Sbjct: 12  DLIERFFKTGTSATEQNENIPLGIGDDCALIKQATDSEIAITTDMLVEGRHFFAGADPEQ 71

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G+ A+    +D+A  GA P   +    + +   +  L+A    + ++A   G  ++ GD
Sbjct: 72  LGRKALAVNLSDLAAMGAEPLGFTLAIAMPKA-DIAWLEAFSKGLLDSANLYGCPLIGGD 130

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T          L ++   +G IP             D + VSG +GD    +  LR ++ 
Sbjct: 131 TTAGP------LTLSITALGNIPQGKAIRRSGAKIEDDVWVSGNVGDARLALAALRHEIP 184

Query: 192 LDGE----LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           L  E    +       TP I+    +  +         G+   ++          ++   
Sbjct: 185 LSAEDLKQVEKRMHQPTPRIELGIGLRDIATAALDISDGLLGDLNHVLKQSQVDAQIFLN 244

Query: 248 ALPVKPAVRGV-CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
            +P    ++    ++    A +  ++ ++      +  E +     S  L     LIG +
Sbjct: 245 QIPKSETLKKQSTDIQNQFAASGGDDYEICFTAPNHQREAIKKL--SKSLDLPLTLIGRI 302

Query: 307 V----ERKGVRLAGLYGVK 321
           +    +   V L    G  
Sbjct: 303 IPIKNKNPQVHLINSDGAT 321


>UniRef50_Q8K9A5 Thiamine-monophosphate kinase n=4 Tax=Buchnera aphidicola
           RepID=THIL_BUCAP
          Length = 323

 Score =  150 bits (378), Expect = 9e-35,   Method: Composition-based stats.
 Identities = 50/311 (16%), Positives = 112/311 (36%), Gaps = 32/311 (10%)

Query: 17  QLINSLFM---EAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGG 70
           ++I+  F    +   N      +D A +     + + + LA STD+ V    F       
Sbjct: 7   EIISKFFKNHQKKDKNQIKGIGDDSALIK----IPKNNLLAISTDTLVEGKHFLKNITPK 62

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++   ++    +D+A  GA P +++    + +   +  LK+   S  +      + ++ G
Sbjct: 63  DLAYKSVAVNLSDLAAMGAKPTWITLSITMPKSDSV-WLKSFSKSFFKILNKYKLNLIGG 121

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I  +  G I             GD++ ++G LG+  A +  L+++ 
Sbjct: 122 DTNSGP------LSITLSIYGLIEGKNALLRGNAKNGDLIYITGNLGESAAGLSLLQKKT 175

Query: 191 GLDGE-----LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
            L        L+       P I     +  +         G+ + +        CG +++
Sbjct: 176 FLKNVKICNYLIKKHLKPIPRISEGIALRNIANAAIDISDGLISDLGHILKNSKCGADIN 235

Query: 246 EAALPVKPAVRGVCELLGLD-----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
              +P+    + + +   +D     ALN   + +L   + +   +++  A+         
Sbjct: 236 LNTIPIS---KILTDNFKIDEYLNWALNSGEDYELCFTISKKNIKKLNVAIKKKI--IKC 290

Query: 301 ALIGEVVERKG 311
             IG +   + 
Sbjct: 291 TCIGYITSAEK 301


>UniRef50_B0MTR2 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MTR2_9BACT
          Length = 310

 Score =  150 bits (378), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 60/299 (20%), Positives = 107/299 (35%), Gaps = 26/299 (8%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIGK 74
           I  +F     N +    +D     L      G+ L F+ D    +  F         +G+
Sbjct: 10  IRDMFAAIPRNGFDGIGDDCTVFPLGS----GESLVFTADLLAENIHFLRRATSARELGR 65

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
            ++    +DVA  GA P        +   LP   ++  +    + +    + +V GDT  
Sbjct: 66  KSLAVNLSDVAAMGARPIATLLSLAIPHDLPEGWIEDFMEGYRDLSAQYDVGLVGGDTTA 125

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNLREQLG 191
              G    L +N   +G I  +          GD++ V G+LG+ GA    IL  R    
Sbjct: 126 SDSG----LVVNVTAIGRIADSHIKRRSDARPGDLIAVGGSLGESGAGLRDILAGRYDTP 181

Query: 192 LDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           L  ++  + A        L + P V A+ D +  G+ + +       G G E+    +P 
Sbjct: 182 L-AQIHRNPAPQVAEGIWLGERPEVHAMMDISD-GIASDLRHILHQSGVGAEVDTECIPT 239

Query: 252 KPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
              +          A++   + KL+  V   +A  +L+       G +   IG +    
Sbjct: 240 PVDLET--------AVSGGEDYKLLFTVAPESANTLLSNYR-LRFGDEFHFIGRITGGN 289


>UniRef50_B7AVF9 Putative uncharacterized protein n=1 Tax=Bacteroides pectinophilus
           ATCC 43243 RepID=B7AVF9_9BACE
          Length = 305

 Score =  149 bits (377), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 58/274 (21%), Positives = 108/274 (39%), Gaps = 20/274 (7%)

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ A+    N +A  G  P  ++    + +    + LK ++  +    R  G  I   D 
Sbjct: 38  GRYAVIDACNALACRGGEPEGINAAVTIPDSYDEKLLKKLIADIDAQCRTCGTHI--EDV 95

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
            V     + K  I  +  G     +  G Q       ++ SG++G  G  I+N+ +    
Sbjct: 96  AVSTSQHIRKPVITASAFGRSSEEMPAGMQKAGGNLDIIASGSIGMSG--IMNVLDSHMD 153

Query: 193 DGELVSDCAVLTPLIQTLRDIPGV-----------KALRDATRGGVNAVVHEFAAACGCG 241
           + + V   +V+         +                L  A  GG+ A +   AA  GCG
Sbjct: 154 EAKKVYADSVINAAAADAGKLSVADRASLAAGAGASYLVAAGDGGIYAALWRLAADNGCG 213

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
            +++   +PVK  +  +CEL  ++    ++ G +++  E      ++  L+ +  G DA 
Sbjct: 214 FDINLRDIPVKQEIIEMCELFDINPYELSSTGCMLMTAEDGCG--IVDVLNEN--GYDAV 269

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           +IG   + K  ++  L    R LD+P  E   R 
Sbjct: 270 VIGHTTKEKA-KMMHLEDEVRYLDVPRNEESERF 302


>UniRef50_A0LIX8 Thiamine-monophosphate kinase n=1 Tax=Syntrophobacter fumaroxidans
           MPOB RepID=A0LIX8_SYNFM
          Length = 340

 Score =  149 bits (377), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 62/305 (20%), Positives = 116/305 (38%), Gaps = 24/305 (7%)

Query: 33  AEQEDQARLDLAQLVAEGDRLAFST-DSYVIDPLFFPGG----NIGKLAICGTANDVAVS 87
            +       D+A L   G     +T D+ V +  F         +G+  +    +D+A  
Sbjct: 24  GDVVVGIGDDVAVLNVSGPEYLLATCDAQVENIHFIRAATTPYQLGRKIVAINVSDIAAC 83

Query: 88  GAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINT 147
           G  P++      L     ++ +  +   M E   AAG +IV G       G   ++ I+ 
Sbjct: 84  GGRPKWALVSLALTPDTGVDFVDGLYAGMQEEIHAAGASIVGG----NLSGIRGEIVIDL 139

Query: 148 AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI-LNLREQLGLDGELVSDCAVLTPL 206
           + +G +            +GD++LV+GTLG+  A + L LR +L ++ E           
Sbjct: 140 SLLGTVSPECLILRNGARSGDLVLVTGTLGESRAGLELILRPELEVEQEAGDRVRARHLT 199

Query: 207 I-------QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVC 259
                   + L     + A+ D +  GV   +     A     E+   +LP+ P    V 
Sbjct: 200 PGARLREGRILAATGSIHAMADVSD-GVLGDLGHICRASEVQAEIWPESLPISPECLRVA 258

Query: 260 ELLGLDALNFANEG----KLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV-ERKGVRL 314
           E+   DA+ +A  G    +L+   +     ++   L +   G    +IG +  + + V +
Sbjct: 259 EVARCDAVQWALSGGEDYELLFTADPRRVPEIRGRLEAET-GTSCHVIGRITGKGEAVLV 317

Query: 315 AGLYG 319
               G
Sbjct: 318 RSREG 322


>UniRef50_C8R1R1 Thiamine-monophosphate kinase n=1 Tax=Desulfurivibrio alkaliphilus
           AHT2 RepID=C8R1R1_9DELT
          Length = 341

 Score =  149 bits (376), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 65/288 (22%), Positives = 103/288 (35%), Gaps = 24/288 (8%)

Query: 55  FSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLK 110
            +TD+ V    F     P   +G+ A+    +D+A  G  PRY      L E      L+
Sbjct: 48  VTTDTLVEGVHFDRRWHPPRLLGRKAVAVNMSDIAAMGGTPRYALLSLGLGEAENPAWLE 107

Query: 111 AVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVL 170
            ++  +AE   A G  ++ GDT        ++L +    +G  PA+         AGD +
Sbjct: 108 MMLDGLAEAVAAYGAVLIGGDTVKSP----ERLLLTVTIIGESPASRACLRSGGQAGDSI 163

Query: 171 LVSGTLGDHGATILNLREQLGLDGELVSDCA------VLTPLIQTLRDIPGVKALRDATR 224
            V G LG     +   R  L  D +                L + L     V A+ D + 
Sbjct: 164 WVGGPLGLAAGGLELCRRDLAADPQWQEAVQAHLDPPAQVELGRRLAAAGVVHAMMDLSD 223

Query: 225 GGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFA----NEGKLVIAVE 280
            G+   +    AA G G E+    LPV   +     +   D LN+A     + +L+   +
Sbjct: 224 -GLATDLAHICAASGVGAEVEAELLPVPDLLHRAAAVCQADPLNWALCGGEDYRLLFTAD 282

Query: 281 RNAAEQVLAALHSHPLGKDAALIGEVVE----RKGVRLAGLYGVKRTL 324
               +  +A L           IG +        GV L    G  R +
Sbjct: 283 PAR-DGAIAELGRDLADTTLTRIGRLTAPPPGGPGVLLRTADGQSREI 329


>UniRef50_Q5QVE6 Thiamine monophosphate kinase n=2 Tax=Idiomarina RepID=Q5QVE6_IDILO
          Length = 331

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 64/319 (20%), Positives = 112/319 (35%), Gaps = 23/319 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYVIDPLF---FPGGNI 72
            LIN  F     +    +       D A +    +  L   TD+ V    F    P   I
Sbjct: 7   SLINEYFTHR--SAKRGDVAMGIGDDGAVVRPMPEHDLVIVTDTLVEGVHFDMTTPPRAI 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  ++    +D+A  GA P ++S    L   +  + L+     + E        ++ GDT
Sbjct: 65  GHKSVAVNLSDLAAMGAQPCWISLALTLPR-MDEDWLQEFSGGLDEICSYYDCQLIGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I     G +P+          AGD + VSG+LGD G  +   + ++  
Sbjct: 124 TKGP------LTITITAHGQLPSGSAIPRSGAKAGDWIYVSGSLGDAGLGLQVTQNKVST 177

Query: 193 DG----ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
            G    +++      TP +   + + GV +       G+ A +       G   +L    
Sbjct: 178 TGRHLQQVIERLHYPTPRVALGQSLRGVASSCIDISDGLLADLRHLMTEAGTQAQLELEK 237

Query: 249 LPVK---PAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           LP+         V + L L AL   ++ +L   +      + +  L +H   +    IG 
Sbjct: 238 LPLSLALTETLQVDDALAL-ALTAGDDYELCFTLPEEHRGR-METLTTHLKTRPV-CIGR 294

Query: 306 VVERKGVRLAGLYGVKRTL 324
           V   +   +   Y  +  L
Sbjct: 295 VANGESGDIQLRYNGEDWL 313


>UniRef50_Q5FNA0 Thiamin-monophosphate kinase n=1 Tax=Gluconobacter oxydans
           RepID=Q5FNA0_GLUOX
          Length = 325

 Score =  148 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 67/310 (21%), Positives = 113/310 (36%), Gaps = 16/310 (5%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGKL 75
           I   F        L  ++D A +       EG+  A STD+ V +  F P      +G+ 
Sbjct: 18  IARHFRPLAGAESLDLRDDCALMRC----PEGEEFAISTDTMVENVHFLPDDPPETLGRK 73

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEG--LPMETLKAVVTSMAETARAAGIAIVTGDTK 133
            +    +D+A  GA P   +    +  G         A    +AE  +  G+ ++ GDT 
Sbjct: 74  LLRCNLSDLAAMGARPHAYTLNVTVTRGGRHDENWFAAFSRGLAEDQQRYGVHLIGGDTT 133

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
            +       L ++    G +  N      T   GD + V+GT+GD    +L L+  L   
Sbjct: 134 SISG----PLVLSATVFGLLRHNTALRRSTARPGDEIWVTGTIGDAALGLLVLQGSLQDP 189

Query: 194 GELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
              +++   L      L     V A  D + G +    H  A   G  + +   A+PV  
Sbjct: 190 SGFLAERYHLPRPRTGLHLHGIVSAAMDISDGLIQDCGH-IAEESGVQLVVDAEAVPVSS 248

Query: 254 AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           A   +     +  L   ++ +L++      +  + AA  +         IG V    GVR
Sbjct: 249 AAASLGHEWLMRRLCGGDDYELLLTCAPERSAALQAACQAAE--VPVHRIGTVRTGSGVR 306

Query: 314 LAGLYGVKRT 323
           L    G +  
Sbjct: 307 LLDGEGHEIV 316


>UniRef50_B9XDK5 Thiamine-monophosphate kinase n=1 Tax=bacterium Ellin514
           RepID=B9XDK5_9BACT
          Length = 310

 Score =  148 bits (374), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 67/317 (21%), Positives = 117/317 (36%), Gaps = 34/317 (10%)

Query: 17  QLINSLFMEAFANPWL--AEQEDQARLDLAQLVAEGDRLA-FSTDSYVIDPLFF---PGG 70
           +LI  L     AN  L     +D A LDL       DRL  F TD+ V    F    P  
Sbjct: 5   ELIGKLTRSLPANKSLVTGAGDDCAVLDLGIP----DRLVLFKTDAVVEGFHFTSETPPE 60

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G+ A+    +D+A     P        L     ++ ++ +   + E AR   ++I  G
Sbjct: 61  KVGRKALGRCISDIAAMAGTPNSALITLALPRHYDLDYVEGIYAGLGELARKFDVSIAGG 120

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           +T        +++ I+ + +G +            AGD + V+G LG   +      + L
Sbjct: 121 ETTTNP----ERILISISLLGTVEREKCIFRSGALAGDAIFVTGELGGSISG-----KHL 171

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
             +  L             LRD   + ++ D +  G+   +     A   G EL  +A+P
Sbjct: 172 DFEPRLTE--------AHWLRDHFAIHSMIDLSD-GLAGDLRHLLKASHVGSELMASAIP 222

Query: 251 VKPAVRGVCELLG------LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           V    +   +         L AL    + +L+  +    A  +L            + IG
Sbjct: 223 VSREAKLASKAESSAKPPLLAALTDGEDFELLFTIASKDAVPLLDGWKHQFPKVKLSCIG 282

Query: 305 EVVERKGVRLAGLYGVK 321
           +V   +G+ L    G++
Sbjct: 283 KVTAGEGINLRDKQGIR 299


>UniRef50_D1A2J3 AIR synthase related protein n=1 Tax=Thermomonospora curvata DSM
           43183 RepID=D1A2J3_THECD
          Length = 352

 Score =  148 bits (374), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 69/311 (22%), Positives = 113/311 (36%), Gaps = 31/311 (9%)

Query: 38  QARLDLAQLVAEG-DRLAFSTDSYVIDPLFFPGG-------NIGKLAICGTANDVAVSGA 89
            A+ D A    +G   L   +D YV  P F           +IG        +D+A  GA
Sbjct: 42  DAQDDCAVFRLDGVQELVVGSD-YVRGPKFGLYELGYLDDYDIGYYLAMANFSDIAAMGA 100

Query: 90  IPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAG 149
            P  L       + +P E    V+  + +     G   V GD      G  ++L ++ + 
Sbjct: 101 QPIALLSVVRYPKTMPDERFAQVLQGINDACARVGAPNVGGD-----IGTAERLILSASA 155

Query: 150 MGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT--------ILNLREQLGLDGELVSDCA 201
           +G + A           GD L ++G  G   A         + + R     +  L++   
Sbjct: 156 VGVVEAGRSLLRGGARPGDRLCITGPTGVAAAAQKYFGKLDVADTRLSPQAEELLLNAWK 215

Query: 202 VLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGV 258
               L+   ++L     V + +D +  G+ A +   AA  G G  + E ALPV  AV  V
Sbjct: 216 RPQALVPEGRSLSTSGLVTSCQD-SSDGLKAGIESIAARSGVGFTVEEDALPVVGAVEEV 274

Query: 259 CELLGLD--ALNFANE--GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
            +L   +   L   +    +L+  V     E++     +H        IG   E   + L
Sbjct: 275 AKLSDTELTPLLLGDSVDFQLIFTVPEEHVEELQEIFAAHGHSA-FHDIGFATEEPDLLL 333

Query: 315 AGLYGVKRTLD 325
            G  G+ R L 
Sbjct: 334 RGSDGITRRLP 344


>UniRef50_D1C275 Thiamine-monophosphate kinase n=1 Tax=Sphaerobacter thermophilus
           DSM 20745 RepID=D1C275_SPHTD
          Length = 342

 Score =  148 bits (373), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 61/324 (18%), Positives = 110/324 (33%), Gaps = 24/324 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNI 72
            +I+ +              D A +        G  L F+TD  V +  F         +
Sbjct: 20  DMIDGVVSATLPRRLRMGIGDDAAV---WRPRPGRDLVFTTDILVQNVHFRLDWMDWQAV 76

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +DVA  GA PR       L        +  +   M    R  G+ +  GD 
Sbjct: 77  GHKALAVNLSDVAAMGAQPRLALVSLALTGSERDREVTDLFRGMNALGRRHGVVVAGGDL 136

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIH--WGAQTLTAGDVLLVSGTLGDHGATILNLREQ- 189
                G    + ++   +G   A             GD++ V+G LG   A +   ++Q 
Sbjct: 137 SASPNG----VIVSVTVIGETSAGRRAVMTRDGARPGDIIGVTGPLGMAAAGLRVFQQQL 192

Query: 190 --LGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
             L  +  +    +   P ++   L    GV+A  D +  G+   + +   A G    + 
Sbjct: 193 LTLDGNPAMREAYSRPKPRVREGRLLARAGVRAAMDLSD-GLLGDLPKMCQASGVSAVID 251

Query: 246 EAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
            A +P+  A++   +     AL    + +L+         +V  A     L      IGE
Sbjct: 252 IARVPIPNAIKWNFDDWFDLALRGGEDYELLFTAPPAVFARVCRAFRLAGLHGPWR-IGE 310

Query: 306 VV----ERKGVRLAGLYGVKRTLD 325
           +V    +   V++    G    ++
Sbjct: 311 IVKAGAKGPEVKIREASGKVEEVE 334


>UniRef50_Q1IHF6 Thiamine-monophosphate kinase n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IHF6_ACIBL
          Length = 318

 Score =  147 bits (372), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 67/326 (20%), Positives = 112/326 (34%), Gaps = 34/326 (10%)

Query: 16  QQLINSLFMEA----FANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----F 67
           + LI  +   A    F+       +D A LD       G  L  +TD  + +  F     
Sbjct: 6   RALIERIRRRASSRKFSAITRGIGDDCAVLD----PPPGHELLVTTDFCLENVHFRREWH 61

Query: 68  PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAI 127
           P   +G   +    +D+A  G  P        L   +P + +      +   A    + +
Sbjct: 62  PAKAVGHRCLVRGLSDIAAMGGDPLAAFLSLALPAEIPQKWVDGFFDGLLALAERWKVPL 121

Query: 128 VTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR 187
             GD     +G +  + +    +G++P            GDVL V+GTLG   A +   R
Sbjct: 122 AGGDIAQSPQGVMADIMV----LGSVPRGKAILRSGGKPGDVLYVTGTLGLSVAALQAFR 177

Query: 188 EQLGLDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
                  +         P I     LR+     A+ D +  G++  +       G G  +
Sbjct: 178 AGKKPTAKSTPRHFFPDPRIDIGRLLRERKLATAMIDLSD-GLSTDLSHICDESGVGAVV 236

Query: 245 SEAALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
              ++P       V    GL+ ALN   + +L+            A +     G     I
Sbjct: 237 YATSVPY------VGGENGLEFALNGGEDYELLFTANPR------ARVPKEIDGVPVTAI 284

Query: 304 GEVVERKGVRLAGLYGVKRTLDLPHA 329
           GE+V+R+G+ L    G    L  P  
Sbjct: 285 GEIVQRRGMWLEDKRGKVAKL-RPRG 309


>UniRef50_A0B852 Thiamine-monophosphate kinase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B852_METTP
          Length = 325

 Score =  147 bits (372), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 59/274 (21%), Positives = 109/274 (39%), Gaps = 21/274 (7%)

Query: 42  DLAQLVAEGDRLAFSTDSYVID---PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGF 98
           D A +  +GD L  +TD    +   P       IG ++     +D+A  GA P  +    
Sbjct: 43  DCAVVELDGDYLVVTTDMLHRETDFPDQATPWQIGWMSAAVNLSDIAAMGAEPLGVLIAS 102

Query: 99  ILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIH 158
            +     +E ++ +   + +  +A G  ++ GDT   +     +L I    +G +     
Sbjct: 103 GIPPETDLEFVEEIFEGIRDCVKAHGTEVLGGDTDAHR-----ELTICGTALGRVSRERI 157

Query: 159 WGAQTLTAGDVLLVSGTLGDHGATILNLR-EQLGLDGELVSDCAVLTPLIQTLRDIPGVK 217
              +    GD+L  +G+LG  GA +  L+  ++ L   L+  C  +   I  L     V 
Sbjct: 158 LRRRGARPGDLLCTTGSLGGAGAGLKALKIGRIDLARRLLEPCPRVREGI-ALAGTGAVT 216

Query: 218 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD---ALNFANEGK 274
           A+ D +  G+   +H+ A A G G  +    +P+   VR + E         L    + +
Sbjct: 217 AMMDNSD-GLALSLHDLAEAGGTGFLVECERIPIAEEVRAIAESDDEALEMVLRAGGDFE 275

Query: 275 LVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE 308
           L++ V  +  +    A        +  +IG  VE
Sbjct: 276 LLLTVREDMIDDARKAC-------ELTVIGRAVE 302


>UniRef50_B5Y8K3 Hydrogenase expression/formation protein HypE, putative n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y8K3_COPPD
          Length = 310

 Score =  147 bits (371), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 57/286 (19%), Positives = 100/286 (34%), Gaps = 18/286 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+     I  L    +         D + L  + +V     +  STD     P+     +
Sbjct: 3   GKVPVSYIGDLVERFYGKRRQEVLIDASNLTDSAVVDLDAPMVVSTD-----PITGADNH 57

Query: 72  I-GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +  +LA+   ANDV V+G  P       +L    P + ++ +   + E        +V G
Sbjct: 58  VVTQLAVHINANDVRVAGGEPVAFLAVLLLPTNFPQKDIEGMFEHLHEGLDYENAQLVGG 117

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            ++     AV K  +     G        G   +  G  +  +GTLG     IL  R   
Sbjct: 118 HSEFTS--AVTKPVVVGTMFGK--RIRVLGKDLVRPGQHVFFAGTLGREAMMIL--RGSY 171

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
           G D   VS    + P++    ++P +    D T GG+ A + E       GIE S     
Sbjct: 172 GDDILKVS----VKPIMDVALNVPSLVFAHDLTEGGLVAGLWELTRGTSLGIEASFPESY 227

Query: 251 VKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
           +   +  +      +     + G +++  E     ++   L    L
Sbjct: 228 LDQELIQLSRRFQFNPYKIISSGSVLLVCENER--EMREKLEEEHL 271


>UniRef50_B9ZS01 Thiamine-monophosphate kinase n=1 Tax=Thioalkalivibrio sp. K90mix
           RepID=B9ZS01_9GAMM
          Length = 324

 Score =  147 bits (371), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 78/319 (24%), Positives = 120/319 (37%), Gaps = 30/319 (9%)

Query: 17  QLINSLFMEAFA---NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GG 70
            LI   F E      +  L   +D A L +      G  L  S D+ V    +FP     
Sbjct: 9   DLIRRYFAEPAGTSPDVRLGIGDDAALLGVQA----GHELVVSVDTMVEGTHYFPDHPPA 64

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A+    +D+A  GA P        L   +  + L A        A  A + +V G
Sbjct: 65  SLGHKALAANLSDLAAMGADPLGAVLSLTLP-SVDHDWLAAFSRGFLALAEQASVPLVGG 123

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL--NLRE 188
           DT            I+   +G +PA           GD L+VSG LG   A +     R 
Sbjct: 124 DTTRGPGA------ISVTVLGQVPAGQALRRAGARPGDRLVVSGALGGAAAGLAFEKQRR 177

Query: 189 QLGLDGELVS-DCAVLTPLIQTLRDIPG----VKALRDATRGGVNAVVHEFAAACGCGIE 243
             G   +  S DCA L      L    G     +A+ D + G +   +   AAACGCG  
Sbjct: 178 AQGRPPDEESPDCARLFWPSARLALGRGLRNRARAVIDISDGLLAD-LGHLAAACGCGAR 236

Query: 244 LSEAALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           +  + LPV P + G  E +  D  L    + +L+ A+      ++L+      +     +
Sbjct: 237 VDWSQLPVDPLLEGQPEEMVRDCVLAGGEDYELLFALPPTEPLELLSL----SVRTSLTV 292

Query: 303 IGEVVERKGVRLAGLYGVK 321
           IGE      + +   +G +
Sbjct: 293 IGEFTSGSDIEVVDAHGAR 311


>UniRef50_D1BMW6 Thiamine-monophosphate kinase n=3 Tax=Veillonella
           RepID=D1BMW6_VEIPT
          Length = 326

 Score =  147 bits (371), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 61/297 (20%), Positives = 110/297 (37%), Gaps = 18/297 (6%)

Query: 38  QARLDLAQLVAE-GDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVSGAIPR 92
               D A    E       STD+ V    F        ++G   +    +DVA  G IPR
Sbjct: 29  GIGDDCAIYKTEQNTEQLISTDTMVEGIHFSFHYMTPYDVGYRLMTANLSDVAAMGGIPR 88

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
            +     + + +    L  +   + +      + I+ GDT   +      +      +G 
Sbjct: 89  QIVLSLAVSDHIDTAILDEIYRGIKDQCMRYQLNILGGDTVRTEG----PMVWTVTIIGE 144

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-GLDGELVS--DCAVLTPLIQT 209
           IP            GDV+ ++  +G     +  L   L G D   V          L Q 
Sbjct: 145 IPKGTAVMRSGAKVGDVVGLTNYVGYAATGLGALSYNLVGYDMTKVGHQRPEPQIELGQK 204

Query: 210 LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNF 269
           LR + G+ ++ D +  G+ + ++E A A    I   E A+P+      + + L  + +++
Sbjct: 205 LR-LLGIHSMNDISD-GLGSELNEIAVASNVSIVFEEQAIPLHEETYELAKHLQTNPVDY 262

Query: 270 ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER-KGVRLAGLYGVKRTLD 325
           A  G     +   A + +L+ L          LIGEV+     V++  L    +T++
Sbjct: 263 ALYGGEDFQLVFTAPKSLLSELEKL---AGITLIGEVLSGPPRVQMVTLDKTIKTIE 316


>UniRef50_A6CFS7 Thiamine-monophosphate kinase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CFS7_9PLAN
          Length = 307

 Score =  146 bits (370), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 58/304 (19%), Positives = 98/304 (32%), Gaps = 39/304 (12%)

Query: 32  LAEQEDQARLDLAQLVAEGDRLAFSTD------SYVIDPLFFPGGNIGKLAICGTANDVA 85
           L   +D A L           L  +TD       +   P        G+ A+    +D+A
Sbjct: 25  LGIGDDTAILQPPAHS----ELLLATDMLMEGAHFTFPPAT--PELAGRKALAVNLSDIA 78

Query: 86  VSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI 145
             G  P        L      E  K+V+  + E A      +  GDT          L I
Sbjct: 79  AMGGSPHSALVSLALPRSRGSEFAKSVMQGIMELAAEFQTQLAGGDTNSWNG----PLVI 134

Query: 146 NTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTP 205
           N A +G    +          GD + V+G LG            L     +    A    
Sbjct: 135 NVAIIGTADQSHSIKRSGAQPGDWIFVTGALGGS-----LESHHLTFQPRVREAVA---- 185

Query: 206 LIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD 265
               L +   +K++ D +  G+ + +         G  +    +P+ P V    EL   +
Sbjct: 186 ----LMETVTIKSMIDVSD-GLASDLQHILVESDVGAVIQSKQIPISPRVSS--ELTDAE 238

Query: 266 ----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVK 321
               AL+   + +L+  V     +++      +PL      IG++   +G  L    G  
Sbjct: 239 RLQKALSDGEDFELLFTVSAEQGQRLRD---QNPLSIPLTHIGKITAEQGALLQQTDGST 295

Query: 322 RTLD 325
             L+
Sbjct: 296 TPLE 299


>UniRef50_Q1YU39 Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium
           HTCC2207 RepID=Q1YU39_9GAMM
          Length = 305

 Score =  146 bits (369), Expect = 9e-34,   Method: Composition-based stats.
 Identities = 63/284 (22%), Positives = 106/284 (37%), Gaps = 20/284 (7%)

Query: 32  LAEQEDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGGNIGKLAICGTANDVAVSG 88
           L   +D A L+    V  G +L  ++D+ V     P       I   A+C   +D+A  G
Sbjct: 3   LGIGDDAALLN----VRPGQQLVMASDTLVSSIHFPESATPRQIATRALCVNLSDMAAMG 58

Query: 89  AIPRYLSCGFILE-EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINT 147
           A PR+ +    L  +    E L      +   A    +A+V GDT          L +  
Sbjct: 59  AEPRWFTLALTLPRDKAKAEWLAEFSVGLGHIANQYNLALVGGDTTSGP------LTLTL 112

Query: 148 AGMGAIPANIHWGAQTLTAGDVLLVSGTLGD--HGATILNLREQLGLDGE-LVSDCAVLT 204
             +G +P +        + GD + V+GTLGD   G  I + +    +D + L+       
Sbjct: 113 TLVGEVPVDKALTRGGASIGDSVFVTGTLGDGAAGLKIASNKNSNCIDSDRLLQRFYSPQ 172

Query: 205 PLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGL 264
           P IQ    +  + +       G+ A +     A      +    LP+   V+ +  L  L
Sbjct: 173 PQIQAGLKLRSIASACIDISDGLLADLGHICKASDVSAVIKAEQLPIAADVQQLSALDAL 232

Query: 265 DA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
              L+  ++ +L   V       V   +    L  DA+ IG + 
Sbjct: 233 QWALSGGDDYQLCFTVATGQLPTVEGWIEKGEL--DASRIGFIE 274


>UniRef50_C3K2R7 Thiamine-monophosphate kinase n=3 Tax=Gammaproteobacteria
           RepID=C3K2R7_PSEFS
          Length = 321

 Score =  146 bits (369), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 64/314 (20%), Positives = 110/314 (35%), Gaps = 25/314 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFPGGN---I 72
           +LI + F  A               D A L +  G++LA STD+ V    F    +   +
Sbjct: 5   ELIRNYFAAAPCAQGGEGIALGIGDDCALLALPTGEQLAISTDTLVAGVHFADPCDPFLL 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ ++    +D+A  GA P   +        +  + L+     +   A+  G+ +V GDT
Sbjct: 65  GQRSLAVAVSDLAAMGAHPLAFTLALTTP-TVDADWLQRYAQGLNAMAQRCGVGLVGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L +    +G +PA           GD+L V G LG+    +  +  Q   
Sbjct: 124 TRGP------LSLTLTVLGRVPAGQALTRSGARPGDLLCVGGELGNAAGALPLVLGQRSA 177

Query: 193 DGELVSDC-----AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           D  +         +    L   L       +  D + G +    H  A A    + +   
Sbjct: 178 DAAIADPLLAHYWSPQPQLALGLALRGKATSAMDISDGLLADCGH-IATASQVSLLIERQ 236

Query: 248 ALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
            LP+  A+      +   + AL+  ++  L   +       +LA       G    +IG 
Sbjct: 237 RLPLSTALLAFVGDDEARVAALSGGDDYVLAFTLPPAELAPLLAD------GLPIHVIGR 290

Query: 306 VVERKGVRLAGLYG 319
           V   +GV L    G
Sbjct: 291 VEPGQGVTLLDADG 304


>UniRef50_Q607V1 Thiamine-monophosphate kinase n=1 Tax=Methylococcus capsulatus
           RepID=Q607V1_METCA
          Length = 325

 Score =  146 bits (369), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 61/297 (20%), Positives = 103/297 (34%), Gaps = 23/297 (7%)

Query: 29  NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGTANDVA 85
           N  +   +D A L+         RLA +TD+ V    FF   +   +G  A+    +D+A
Sbjct: 23  NTEIGIGDDCAVLNFTAAA----RLALTTDTLVAGIHFFSDTDPTRLGHKALAVNLSDLA 78

Query: 86  VSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI 145
             GA PR+      L E  P E + A        A    + ++ GDT          L I
Sbjct: 79  AMGARPRWALLALTLPENDP-EWIAAFAQGFFRLAERHRVQLIGGDTTRGP------LAI 131

Query: 146 NTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL--DGELVSDCAVL 203
               +G +             GD + ++G++G  G   L +R+   L  D E +      
Sbjct: 132 TVHALGTVDGRPGVKRAGAKPGDAIYLTGSIGLAGLG-LRIRQGAYLVPDEEALDRLEAP 190

Query: 204 TPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELL 262
            P     +R      A  D +  G+ A +         G E+   +LP+   V       
Sbjct: 191 QPRTDFGIRLGEFASAGIDVSD-GLAADLGHILEQSSVGAEVDWESLPLSAGVGRYVADS 249

Query: 263 G--LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGL 317
           G     L   ++ +L        A+ + +A  +         IG +    G+ +   
Sbjct: 250 GDWQMPLVAGDDYELCFTASPAYAQAIASA--ADATATPVRRIGTIRTGSGLIIRRR 304


>UniRef50_B2UPF2 Thiamine-monophosphate kinase n=2 Tax=Verrucomicrobiaceae
           RepID=B2UPF2_AKKM8
          Length = 298

 Score =  146 bits (368), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 65/284 (22%), Positives = 102/284 (35%), Gaps = 26/284 (9%)

Query: 30  PWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYVIDPLFFPGGN---IGKLAICGTANDVA 85
           P     E     D A +   G+R L   TD  V    F PG +   IG+ A+    +D+ 
Sbjct: 24  PSNPSLETGPGDDCAIIRGSGNRQLLLKTDCVVEGMHFLPGTDPELIGRKALARAVSDIG 83

Query: 86  VSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI 145
             G  P +      +    P+  ++ +   M   AR  GI+I  G++  +     D L I
Sbjct: 84  AMGGTPLHALVTLFVHADRPISQVEGIYRGMGRLARQFGISIAGGESSGLP---ADGLII 140

Query: 146 NTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTP 205
           N A  G + A       T  AGD++ V+GTLG    T       L     +         
Sbjct: 141 NVALTGEVEAGKAVLRSTARAGDLIAVTGTLGGSFPT----GHHLSFTPRVREGG----- 191

Query: 206 LIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD 265
               L       ++ D +  G+   +   AAA G G  + E  LPV+P            
Sbjct: 192 ---ILAASGVATSMMDLSD-GLGTDLPRLAAASGLGFRIHEELLPVRPGFTAA------Q 241

Query: 266 ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
           A+    + +L++       E+       H       +IGE+   
Sbjct: 242 AVGDGEDYELLVTFRPGDRERAARLAAEHFPETPLTVIGEMTAE 285


>UniRef50_B4WXS9 Thiamine-monophosphate kinase n=1 Tax=Alcanivorax sp. DG881
           RepID=B4WXS9_9GAMM
          Length = 333

 Score =  143 bits (362), Expect = 6e-33,   Method: Composition-based stats.
 Identities = 65/310 (20%), Positives = 110/310 (35%), Gaps = 28/310 (9%)

Query: 17  QLINSLFMEAFAN-PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGGNI 72
            LI   F     +   L   +D A L    +   G +L  + D+ ++D   P      ++
Sbjct: 34  SLIRRYFHHRQGDTVVLGPGDDGALL----VPPAGQQLVMTQDTSLVDRHFPADMAPADV 89

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G   +    +D+A  GA P +      L E +  + L      M E A  AGI++V GD 
Sbjct: 90  GYRCLAVNLSDLAAMGANPLWFLLSLTLPE-VDEDWLAEFSRGMFELADQAGISLVGGD- 147

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
             + RG    L ++    G++P  +         GD + + G  G     +   +     
Sbjct: 148 --ITRG---PLAVSIQATGSVPPGLALRRDGARVGDQICLGGVTGAGLLGLEQWQAGQRH 202

Query: 193 DGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVK 252
              +             +       A  D + G +  + H   A+ G G  L EAALP  
Sbjct: 203 GPAIGHFRRPRPQWELGMALRGQASACIDISDGVLADLSHILQASGGLGACLDEAALPED 262

Query: 253 PAVRGVCELLGLDALNF--ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
           P V   C      AL     ++  L+  +             + P+ +    +G+V  + 
Sbjct: 263 PPVLAGCSADKQRALQLQGGDDYLLLFTLP-----------AAQPVPRGCYCLGQVDAQP 311

Query: 311 GVRLAGLYGV 320
           G+RL    G 
Sbjct: 312 GIRLRQRNGA 321


>UniRef50_Q31FT3 Thiamine-monophosphate kinase n=1 Tax=Thiomicrospira crunogena
           XCL-2 RepID=Q31FT3_THICR
          Length = 322

 Score =  143 bits (362), Expect = 7e-33,   Method: Composition-based stats.
 Identities = 61/315 (19%), Positives = 113/315 (35%), Gaps = 27/315 (8%)

Query: 17  QLINSLFME---AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG--- 70
            +I + F       +   +   +D A L        G++L   TD+ +++ + FP     
Sbjct: 6   DVIETFFKPLSSVASVDEIGIGDDGAVLSC----LAGNQLVVVTDT-LVEGVHFPVKTSA 60

Query: 71  -NIGKLAICGTANDVAVSGAIPRYLSCGFIL-EEGLPMETLKAVVTSMAETARAAGIAIV 128
            NI   A+    +D+A  GA P + S    L  E      L+     + + A    I +V
Sbjct: 61  YNIAWKALAVNLSDLAAMGATPAFYSLALSLPPEKNNQAWLELFAGGLKQLASLYNIPLV 120

Query: 129 TGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
            GDT        D+L I     G +        +     D++ VSG LG+ G  +  +++
Sbjct: 121 GGDTTRS-----DRLTITITAQGWVETGNAILRKGAQPDDLIYVSGVLGEGGLGLKAVQQ 175

Query: 189 QLGLDGELVSDCAVLT---PLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
               +    S    L    P +     + G+         G+ A +    ++      + 
Sbjct: 176 HWD-EASYASAIQKLNQPSPQVTLGYYLKGLATSAIDVSDGLLADLKHILSSSQVSAWVD 234

Query: 246 EAALPVKPAVRGVCELLG--LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
              +PV  ++R   +        L   ++ +L   V  +    V     +  LG     I
Sbjct: 235 VDLIPVSDSMRTYLQQSNDWSLPLIAGDDYELCFTVHPDNQASVQDL--AKTLGVSLTKI 292

Query: 304 GEVVERKG-VRLAGL 317
           G++V  +G V+L   
Sbjct: 293 GQIVAGEGDVQLKNA 307


>UniRef50_B5JUN1 Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium
           HTCC5015 RepID=B5JUN1_9GAMM
          Length = 305

 Score =  143 bits (362), Expect = 8e-33,   Method: Composition-based stats.
 Identities = 65/297 (21%), Positives = 113/297 (38%), Gaps = 26/297 (8%)

Query: 32  LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP----GGNIGKLAICGTANDVAVS 87
           L   +D A L        G RLA S+D+ +I    FP       +G  A+    +D+A  
Sbjct: 13  LGPGDDAAILQA----PAGYRLATSSDT-LIAGRHFPENTVPEAVGHKALAVNLSDLAAM 67

Query: 88  GAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINT 147
           GA P ++S    L E      L+   +     A   G+A++ GDT          L +  
Sbjct: 68  GAKPAWVSLALTLPEA-SEVWLRGFASGFGALAAEYGVALIGGDTTRGP------LSVTL 120

Query: 148 AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLI 207
              G +P +          G+ + VSG LG     +  + +   L  +         P +
Sbjct: 121 TVTGFLPESQALLRSGAQIGESVYVSGRLGAAAQELGQVLQGGSLSPDQRRHLDYPQPRV 180

Query: 208 QTLRD-IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
           +  +  +P   +  D + G ++   H  AAA    +++  + LP+  ++  +      +A
Sbjct: 181 ELGQQLLPVASSAMDLSDGLLSDAAH-LAAASELAVDIDLSRLPLAESLASLPRE---EA 236

Query: 267 LNFAN---EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV 320
              A+   + +L+       + + L AL S  LG     +G   E  GV      GV
Sbjct: 237 WALASAGDDYELLFTAPNVESPR-LEAL-SQTLGLPLTRVGRTREGDGVHCFERDGV 291


>UniRef50_Q65TX9 ThiL protein n=4 Tax=Pasteurellaceae RepID=Q65TX9_MANSM
          Length = 331

 Score =  143 bits (361), Expect = 9e-33,   Method: Composition-based stats.
 Identities = 68/317 (21%), Positives = 109/317 (34%), Gaps = 32/317 (10%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGD-RLAFSTDSYVIDPLFFP---GGNI 72
            LIN  F  +   P   +       D A    + D RLA +TD+ V +  F+P      +
Sbjct: 7   DLINRYFALSKQIPRQ-DVILSIGDDCAITQLKADQRLAVTTDTMVENSHFYPTIPPRAL 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P ++S    L +      L      M E      + ++ GDT
Sbjct: 66  GYKAVATNLSDLAAMGATPTWVSLALTLPK-TDSHWLNEFSKGMFEILNRYDVTLIGGDT 124

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE---- 188
               +G +  + I   G+     +          GD + VSGTLGD  A     R+    
Sbjct: 125 ---TKGEIPTVTITAQGL---LGDYALCRHQAKIGDWIYVSGTLGDALAGFYLNRDIYEG 178

Query: 189 -----QLGLDGELVSDCAVLTPLIQ---TLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
                    D  +  +   + P I+   TL       A  D +  G    +         
Sbjct: 179 KKSAVGFDEDFFIQRNLYPI-PRIEFGKTLAKYRLANAALDISD-GFMGDLMHILERSQV 236

Query: 241 GIELSEAALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
              ++   LP+ P +      E   L AL    + +L   V      ++   L   PL  
Sbjct: 237 SAVVNLEDLPLSPQLSAYYGREKAELMALQGGEDYELCFTVSDENKTKLDQYL--APLNV 294

Query: 299 DAALIGEV--VERKGVR 313
               +G++   E   V 
Sbjct: 295 PYTCVGQICAAEDNPVI 311


>UniRef50_B4D453 Thiamine-monophosphate kinase n=1 Tax=Chthoniobacter flavus
           Ellin428 RepID=B4D453_9BACT
          Length = 306

 Score =  143 bits (361), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 65/292 (22%), Positives = 106/292 (36%), Gaps = 35/292 (11%)

Query: 30  PWLAEQEDQARLDLAQL--VAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGTANDV 84
           P  AE    A  D A +    +       TD  +    F P  +   +G  A+C   +D+
Sbjct: 29  PHGAEVLVGAGDDCAVIGRKRDARWQLLKTDVVIEGIHFLPDEDARRVGWKALCRAISDI 88

Query: 85  AVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLF 144
           A  G IP +           P++ +KA+   + + AR   + IV G+T          LF
Sbjct: 89  AAMGGIPAHALITLAAPAATPVDRVKALYAGLRKAARKYDVGIVGGETSRSPG----PLF 144

Query: 145 INTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLT 204
           +N A  G +             GD L V+G LG   A      + L     +        
Sbjct: 145 LNIALTGWVERQQCVLRSGGRPGDSLYVTGRLGGSLAG-----KHLDFQPRIEE----AR 195

Query: 205 PLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGL 264
            L+   +     +A+ D +  G+ A +   AAA  CG  + EA LP+           G 
Sbjct: 196 WLVSHFKP----RAMMDLSD-GLAADLPRLAAASQCGYTIDEACLPLNT---------GC 241

Query: 265 DALNFANEG---KLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
                 ++G   +L+ A+   +A  + AA            IG ++    +R
Sbjct: 242 TPTQAMSDGEDFELLFALPARSATALEAAWKKRFPRLPLTQIGRLIPHSAIR 293


>UniRef50_A5Z7T1 Putative uncharacterized protein n=1 Tax=Eubacterium ventriosum
           ATCC 27560 RepID=A5Z7T1_9FIRM
          Length = 319

 Score =  143 bits (360), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 43/268 (16%), Positives = 105/268 (39%), Gaps = 19/268 (7%)

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           +  + N +   G +P+ L     +      + +  ++ +  ++A +  + I   +   V 
Sbjct: 61  VQRSINSICEKGGVPKSLQLSITMPLEFEEKEVNRMIKNFRKSADSHNVEI---NQCNVY 117

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE----QLGL 192
           RG  +   IN   +G         + ++  G  ++++GTL   G +++  R     +   
Sbjct: 118 RGTTEGPIINIFMIGTT--GNLLKSDSIKPGMDVIMAGTLAIGGTSVIAERYKDKLEGKF 175

Query: 193 DGELVSDCAVLTPL-----IQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
            G  +S+C  L           +    G   +   + GG+ + + E A+    GI++   
Sbjct: 176 SGRFISECLELKDYTSTEKASAIAIDAGAVYMHAVSEGGLFSGLWEVASCVDKGIQVDIN 235

Query: 248 ALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
            +P+   V  + E + ++       G L+I        ++  +L+++  G    +IG++ 
Sbjct: 236 KIPIWQQVIEIAEFMDINPYLLEGSGSLLIVSPDGY--KIEESLNAN--GIYGEVIGKIT 291

Query: 308 ERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           + K   +       R L+ P  + + + 
Sbjct: 292 DNKNRVVINGD-ETRYLEPPRGDEIYKF 318


>UniRef50_B0KL72 Thiamine-monophosphate kinase n=13 Tax=Pseudomonadaceae
           RepID=B0KL72_PSEPG
          Length = 322

 Score =  143 bits (360), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 72/314 (22%), Positives = 114/314 (36%), Gaps = 24/314 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLV-AEGDRLAFSTDSYVIDPLFFPGGN---I 72
           +LIN  F  A               D A L    G++LA STD+ V    F    +   +
Sbjct: 5   ELINHYFAAAPCAQGGEGVALGIGDDCALLDLPPGEQLAVSTDTLVAGVHFPVACDPLLL 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ ++   A+D+A  GA     +    L +  P   L A    ++  A+   ++++ GDT
Sbjct: 65  GQRSLAVAASDLAAMGATAIGFTLALTLPDVGP-GWLSAYADGLSRMAQRCRMSLIGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI-LNLREQLG 191
                     L I     G +P            GD+L V G+LG     + L L E+  
Sbjct: 124 TRGP------LSITVTVFGRVPVGQALRRSGARPGDLLCVGGSLGKAAGALPLVLGEREA 177

Query: 192 LDGELVSDCAVLTPLIQTL----RDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
              +     A     +  L           A  D + G +    H  A A G  +E++ A
Sbjct: 178 PAAQAEPLLAHYWSPMPQLTLGALLRGRATAALDISDGLLADCGH-IAKASGVALEVNLA 236

Query: 248 ALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
            +PV PA+      E     AL   ++  L   +   A   +     +     +   IG 
Sbjct: 237 QVPVSPALEAFLGREAAVRAALTGGDDYVLAFTLPPEALAPL-----AAFDTIEVHTIGR 291

Query: 306 VVERKGVRLAGLYG 319
           V+E +GV L    G
Sbjct: 292 VLEGQGVTLRDAQG 305


>UniRef50_D1CF57 Thiamine-monophosphate kinase n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CF57_THET1
          Length = 334

 Score =  143 bits (360), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 67/321 (20%), Positives = 127/321 (39%), Gaps = 31/321 (9%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF-----PGG 70
           ++L++ L    +    +    D    D+A L    D+   +T    ++ + F        
Sbjct: 13  KRLVDKL--PEYGRDVIVGPGD----DVAVLRTSSDKYLLATIDSQVEGIHFLFEYTGAR 66

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G+ AI    +D+A  G  PR+      L +   ++ ++ +   +   + A G+ ++ G
Sbjct: 67  QLGEKAIAINVSDIASMGGQPRHALVSLALPDSCQLKLVEELYEGIYSASHAYGLDVIGG 126

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI------L 184
           +    + G    L ++   +G +             GD + V+G LG   A        L
Sbjct: 127 NISSSRSG----LLVDVCLLGEVEPEHLVLRSGAAPGDGIYVTGWLGSSAAGFELLCSKL 182

Query: 185 NLREQLGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
              ++   +    S       L +   L     V A+ D +  G+ + +     A G G 
Sbjct: 183 RNCDERIWEELTSSHLTPKARLYEARSLVATGAVSAMIDISD-GLISDLGHILEASGVGA 241

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEG----KLVIAVERNAAEQVLAALHSHPLGK 298
            +    LP+  AVR V   LG DAL +A  G    +L++  +R   + +  A  +   G 
Sbjct: 242 VVYTDRLPIATAVREVASTLGKDALRWALSGGEDYELLLTGDRRVLDGI--ASDNGLGGT 299

Query: 299 DAALIGEVV-ERKGVRLAGLY 318
              LIGE++ +  G++L GL 
Sbjct: 300 PLTLIGEILPQSAGLQLEGLN 320


>UniRef50_Q5WJP9 Thiamine-monophosphate kinase n=3 Tax=Bacillus RepID=Q5WJP9_BACSK
          Length = 330

 Score =  143 bits (360), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 55/266 (20%), Positives = 102/266 (38%), Gaps = 18/266 (6%)

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           IG+ A+    +D+A  GA+P++      +      E L ++   M       G+ ++ GD
Sbjct: 63  IGRKALAINVSDLAAMGAVPQFYLVSIAIPPNWSAEELTSLYEGMRAVGDRYGMDLIGGD 122

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT--ILNLREQ 189
           T  ++    D L ++   +G +             GDV+ V+G +G   A   +L+ R +
Sbjct: 123 TVSIK----DSLVLSVTAIGRVKKGCALFRNQAQPGDVVFVTGPVGGSAAGLELLDQRGR 178

Query: 190 LGLDGELVSDCAVLT-------PLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
            G   E       +         + + L + P   AL D +  G+ +   E A A G  +
Sbjct: 179 FGAFTEQERRYVHMHQEPVPQVEMGKMLAEQPYRVALNDISD-GLASESMEIAEASGVQL 237

Query: 243 ELSEAA-LPVKPAVRGVCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
            L +   L + P +  V     +   LN   + +LV  +  +A      A  +   G+  
Sbjct: 238 VLDQQKVLELSPQMDSVLPEKRVKWSLNGGEDFQLVGTMTDSAFSSCCEA--AQQQGRHL 295

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDL 326
             IG V   +   L      ++ L +
Sbjct: 296 YKIGFVRAGEPAVLLASETGEQALQM 321


>UniRef50_A1AW74 Thiamine-monophosphate kinase n=2 Tax=sulfur-oxidizing symbionts
           RepID=A1AW74_RUTMC
          Length = 309

 Score =  142 bits (359), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 62/303 (20%), Positives = 109/303 (35%), Gaps = 29/303 (9%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYVIDPLFFP----GGN 71
            LI + F   +    LA        D A +  + +  L  S D++ I+ + FP      +
Sbjct: 5   SLIETYF--NWGGSNLANL--GIGDDCAVIDIDANYQLVTSVDTF-IEGVHFPSNTSASD 59

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           I   ++    +D+A  GA  +Y +    L   +  + L    TS+   A   GI +V GD
Sbjct: 60  IAYKSLAVNLSDLAAVGARVKYFTLALTLP-NINKKWLSQFSTSLKSLADEFGIVLVGGD 118

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T       +  + IN    G +  N      +   GD++ VS T+GD       L+    
Sbjct: 119 TT----KGMLSITINVT--GVVKKNKALLRSSAQVGDLIFVSNTIGDAAYAWKQLQNNQT 172

Query: 192 LDGELVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
               +++      P +   Q L DI    A  D +  G+   +         G  ++   
Sbjct: 173 PSEYVINQFNRPKPQLFLGQQLSDI--ANACIDISD-GLEQDLTHILTRSNVGASINLDD 229

Query: 249 LPVKPAVRGVCELLGLDA---LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           +P+   V+   E    D    L   ++ +L           +L AL +         IG 
Sbjct: 230 IPLTYEVKTYIEKTN-DWCLVLAGGDDYELCFTAPVKNM-NLLKALQNKN-NITVTQIGI 286

Query: 306 VVE 308
           + +
Sbjct: 287 IND 289


>UniRef50_C0QQC1 Thiamine-monophosphate kinase n=2 Tax=Hydrogenothermaceae
           RepID=C0QQC1_PERMH
          Length = 317

 Score =  142 bits (359), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 50/297 (16%), Positives = 99/297 (33%), Gaps = 31/297 (10%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPG----GNIGKLAICGTANDVAVSGAIPRY 93
               D A +  +G  + F+ D  + +  F  G     ++G   +    +D+   G  PR+
Sbjct: 29  GFGDDCACVNLDGKLMLFTGDIQLENHHFIKGKIKPEDLGWKLVSINVSDIVACGGKPRW 88

Query: 94  LSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAI 153
                 + E      ++ V   M +     G +++ G+T   +   +D   +        
Sbjct: 89  GFISIGIPESTEYSFIEGVYKGMNDALDRYGFSVIGGNTTSSEEIILDLFLVGET----- 143

Query: 154 PANIHWGAQTLTAGDVLLVSGTLGDHGAT----ILNLREQLGLDGELVSDCAVLTPLIQT 209
                        G+V+L+SG  G   A     +++       +  L+            
Sbjct: 144 --ERFVPRGGAEEGEVILLSGFTGCSRAGLELLLMDRESYEDFEMRLIEKHTRPEARYDL 201

Query: 210 LRDI-PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD--- 265
              I    ++  D +  G+   +       G  + + +  LPV P +   C+  G D   
Sbjct: 202 QNLIQRYARSCIDISD-GLVGDLSHIQKMSGVKLVIEKDKLPVDPDLERFCKKYGKDIYD 260

Query: 266 -ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVK 321
             L    + +LV  V +   E+           KD   IG   +  G+ +    G+K
Sbjct: 261 YILYGGEDYQLVFTVNKQDTEKF----------KDCFKIGYTEKGSGIFIKDEKGLK 307


>UniRef50_A1WVF9 Thiamine-monophosphate kinase n=2 Tax=Ectothiorhodospiraceae
           RepID=A1WVF9_HALHL
          Length = 324

 Score =  141 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 77/327 (23%), Positives = 114/327 (34%), Gaps = 25/327 (7%)

Query: 10  SGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF--- 66
            GG+A   LI   F    A       E     D A L  E   LA   D+ V D  F   
Sbjct: 3   GGGEA--ALIQRYFHGLTAQR--DGVELGVGDDAALLQTETGLLAACCDTLVEDIHFPGD 58

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
            P   +G   +    +D+A  GA P +      L E  P + L+         A   G+A
Sbjct: 59  IPPEALGHRVLAVNLSDLAAVGARPAWTLLSLTLPEKDP-QWLERFSAGFKALADRYGVA 117

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL 186
           +V GDT          L ++   +G +  +          GD + V+GTLGD    +   
Sbjct: 118 LVGGDTTQGP------LSVSVTALGQVAGDHGLRRGGARPGDGVWVTGTLGDAALGLELW 171

Query: 187 REQL------GLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
           +E+       G    L        P +     + G  +       G+ A +       G 
Sbjct: 172 QEREEATALAGDPAYLAGRLFRPEPRVAAGTALLGRASAAIDVSDGLAADLSRVLDESGV 231

Query: 241 GIELSEAALPVKPA-VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
           G  L   ALP   A +    +L  L  L+  ++ +L   +     E+ +A L  H     
Sbjct: 232 GATLELEALPRSQAFIDEQGDLRHL--LHGGDDYELCFTLPAEREEE-MACLREHAA-TP 287

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDL 326
              IG V E  G+R     GV   L+ 
Sbjct: 288 VTRIGTVEETPGLRGVDAGGVVCALEP 314


>UniRef50_B7JUY6 Thiamine-monophosphate kinase n=4 Tax=Cyanobacteria
           RepID=B7JUY6_CYAP8
          Length = 344

 Score =  141 bits (357), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 56/305 (18%), Positives = 110/305 (36%), Gaps = 37/305 (12%)

Query: 35  QEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF-----PGGNIGKLAICGTANDVAVSGA 89
            +D A L     V    +L  +TD  ++D + F     P   +G  A     +D+A  GA
Sbjct: 30  GDDGAILS----VDPAQKLVVTTD-VLVDGVHFSDRTTPPATVGWRAAAANLSDLAAMGA 84

Query: 90  IPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAG 149
            P  ++ G  L   +P+  ++ +   + +  +     IV GD           + ++   
Sbjct: 85  NPIGITVGLALPGEVPVNWVETLYQGLNDCLQCYDTPIVGGDICRSPT-----ITVSITA 139

Query: 150 MGAIPANIHWGAQTLTAGDVLLVSGTLGDH--GATILNLRE-----QLGLDGELVSDCAV 202
            G +  +      +   G  ++V+GT G    G  +L   +      +     L+     
Sbjct: 140 FGTVLPHRIIRRSSAQPGHAIVVTGTHGGSRGGLELLLNPQLGDHLTITEQQALIETHQR 199

Query: 203 LTPLIQTL------RDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVR 256
             P +  L           V  +   +  G+   V +     G G ++  + + + P++ 
Sbjct: 200 PQPRLDVLPHLWEIVGTTEVAGM--DSSDGLGDAVVQICRMSGVGAKIERSQISLPPSLL 257

Query: 257 G-VCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
             V     L   L    + +LV+ +  + A+ ++  L     G  A +IGE+     V L
Sbjct: 258 ALVSPEQALQWGLYGGEDFELVLCLPFDLAKTLVERL-----GNGANIIGEITTEPRVIL 312

Query: 315 AGLYG 319
               G
Sbjct: 313 IDSNG 317


>UniRef50_A1SWW7 Thiamine-monophosphate kinase n=2 Tax=Psychromonas
           RepID=A1SWW7_PSYIN
          Length = 335

 Score =  141 bits (356), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 66/312 (21%), Positives = 116/312 (37%), Gaps = 31/312 (9%)

Query: 17  QLINSLFMEAF----ANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN- 71
            LI+S F  +     +   L   +D A LD    + EG +LA STDS V    FF   + 
Sbjct: 7   DLIDSYFKRSTTVQNSGVALGIGDDCALLD----IPEGYQLAVSTDSLVCGVHFFEDVDP 62

Query: 72  --IGKLAICGTANDVAVSGAIPRYLSCGFILEEGL----PMETLKAVVTSMAETARAAGI 125
             +G  A+    +D+A  GA+P+++S    L  G         L          A    +
Sbjct: 63  YRLGYKALAVNLSDLAAMGALPKWVSLAITLPNGAMVNNNPNWLSEFTRGFFALADKFDV 122

Query: 126 AIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN 185
            +V GDT          L I  +  G +P  +         GD++ VS  +GD    +  
Sbjct: 123 VLVGGDTTKGP------LSITVSVKGIVPRGLALQRNKANLGDLICVSNFIGDGALGLSI 176

Query: 186 LREQLGL-DGELVSDCAVLT-PLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
              +L + + +   D   LT P +     + G+ +       G+   +     A  C   
Sbjct: 177 KLNELAVTNPQYFVDALELTEPRVDLGILLRGLASSCIDISDGLTQDLIHILKASHCAAN 236

Query: 244 LSEAALPVKPAVRGVCELLGLD-------ALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
           ++  +LP+   +R    L  L+       AL   ++ +L+  +  N    +   +     
Sbjct: 237 IAIESLPLSKTMRKEVNLGKLNNDEAVQYALTGGDDYELLFTISENNLRLLEQRIAQQTQ 296

Query: 297 GKDA-ALIGEVV 307
              + ++IG   
Sbjct: 297 PIPSLSVIGRTT 308


>UniRef50_B9KXI5 Thiamine-monophosphate kinase n=1 Tax=Thermomicrobium roseum DSM
           5159 RepID=B9KXI5_THERP
          Length = 341

 Score =  141 bits (355), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 71/330 (21%), Positives = 117/330 (35%), Gaps = 25/330 (7%)

Query: 11  GGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---- 66
           G + + + I  L  +      +   +D A    A     G  L  +TD+ +    F    
Sbjct: 12  GEEELIEQIARLVGDRSNRVSIGIGDDAA----AWRPRAGHELVITTDTLIERVHFRLEW 67

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
                +G  ++    +D+A  GAIPR       +        +      +   AR  G+A
Sbjct: 68  TDWEALGHKSLAVNLSDIAAMGAIPRLAVVDLAVRGTERDRDIADFYRGVQALARRFGVA 127

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPAN--IHWGAQTLTAGDVLLVSGTLGDHGATIL 184
           IV GDT     G    + ++   +G  P +            GD++ V+G +G   A + 
Sbjct: 128 IVGGDTTRSPLG----VAVSITVIGESPRDGHRLLRRDAGRPGDLIGVTGPIGLAAAGLR 183

Query: 185 NLREQLG-LDGELVSDCAVLTPLIQT----LRDIPGVKALRDATRGGVNAVVHEFAAACG 239
            L   L  LDG  V       P  +     L    GV+A  D +  G+   + +   A G
Sbjct: 184 VLERGLKTLDGNPVMQEHYHRPQPRVREGLLLRRCGVRAAMDISD-GLLGDLQKLCRASG 242

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
               +    +PV  A++         AL   ++ +L+ A       +V  A     L   
Sbjct: 243 VAAIVDLERVPVPNAIKWAFPDWEEVALRGGDDYELLFAAPPAVFARVARAFARAGL-LP 301

Query: 300 AALIGEVVE----RKGVRLAGLYGVKRTLD 325
              IG++VE       V L  + G  R  D
Sbjct: 302 PWKIGQLVEAGSAGPIVELRDVTGRCRPAD 331


>UniRef50_Q2S9S1 Thiamine-monophosphate kinase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2S9S1_HAHCH
          Length = 325

 Score =  141 bits (355), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 68/319 (21%), Positives = 120/319 (37%), Gaps = 23/319 (7%)

Query: 17  QLINSLFMEAFAN-PWLAEQ-EDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGGN 71
           +LI+  F   FAN P +    E     D A L     RL  STD+ V     P+      
Sbjct: 5   ELISRYFHAPFANFPNVGRLIETGIGDDCAVLTPLSGRLVISTDTCVSGAHFPVDTSAEM 64

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +   ++  + +D+A  GA P   +    L   +    L+A  + + E+A A  I ++ GD
Sbjct: 65  VAARSLGSSVSDLAAMGAEPVGFTLALTLP-TINEAWLQAFGSQLYESALAWRIPLIGGD 123

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ-- 189
           T          L +    +G +  +          G+ + VSG+LGD  A +  L     
Sbjct: 124 TTKGP------LAVTVTVLGRV-QDQCLYRHGAAPGEDVWVSGSLGDAAAALSLLGRPDA 176

Query: 190 --LGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
               ++  L    A   P ++    + G+         G+ A +    +A  CG  + E 
Sbjct: 177 SLTPIERWLYQRYASPQPRLRLGSMLRGIATAAIDISDGLIADLAHICSASNCGALIEEG 236

Query: 248 ALPVKPAVRG-VCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           A+P+ PA+     +   L+ AL   ++ +L         +     + S       + IG 
Sbjct: 237 AIPLSPALLATFSKEEALNCALEGGDDYELCFTAP----QSTRDLIQSLSADVALSRIGT 292

Query: 306 VVERKGVRLAGLYGVKRTL 324
           + +  GV +       R +
Sbjct: 293 LRKESGVSMQRRGEEIRLM 311


>UniRef50_Q21F21 Thiamine-monophosphate kinase n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21F21_SACD2
          Length = 334

 Score =  141 bits (355), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 71/330 (21%), Positives = 120/330 (36%), Gaps = 47/330 (14%)

Query: 17  QLINSLFM---EAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG--- 70
            LI   F           L   +D A L L         +A S D+ +++ + FP G   
Sbjct: 5   DLIKQYFRNVSPVVEGTTLGNGDDCALLQLKP----NQTMAVSVDT-LVEGVHFPCGASA 59

Query: 71  -NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            +I + A+    +D+A   A PR+++    L +    + L A    +     A    ++ 
Sbjct: 60  NDIAQRALRTALSDLAAMAATPRWVTLALTLPQHNS-DWLSAFSEGLRADLHAFNCELIG 118

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           GDT    RGA   L I+   MG +             GD + V+ TLG+  A++L +  +
Sbjct: 119 GDT---TRGA---LTISVQVMGVVENYPALTRAGAKVGDGIFVTHTLGNGAASLLQVLGK 172

Query: 190 LG---LDGELVSDCAVLTPLIQ----TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           L    L   L S+   L    +      + +  V         G+ A +     A G G 
Sbjct: 173 LQSLALPNALCSELDDLFYRPELAFYVAQQLHAVATSAIDISDGLVADLKHICTASGVGA 232

Query: 243 ELSEAALPVKPAVRGVCE----------------LLGLDALNFANEGKLVIAVERNAAEQ 286
           +++ A LP     + + +                LL   AL   ++ +L      +A  +
Sbjct: 233 KVNVAQLPYSATAKSLAKGIENTALNSERLTAQQLLQQWALYGGDDYQLCFTAPAHAVAE 292

Query: 287 VLAALHSHPLGKDAALIGEVVERKGVRLAG 316
           +            A  IG VV  +GV+L  
Sbjct: 293 L-----KEQTPLAATQIGVVVAEQGVQLHN 317


>UniRef50_C9YEU1 Thiamine-monophosphate kinase n=1 Tax=Curvibacter putative symbiont
           of Hydra magnipapillata RepID=C9YEU1_9BURK
          Length = 354

 Score =  140 bits (354), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 77/335 (22%), Positives = 110/335 (32%), Gaps = 35/335 (10%)

Query: 12  GQAMQQLIN-SLFMEAFAN---PWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLF 66
           GQ M  L   +L    F     P   +       D A L    G + A S+D  V    F
Sbjct: 15  GQRMSDLGEFALIARYFERSQHPLPTQVVLGIGDDCALLQPTPGMQWAISSDMLVSGRHF 74

Query: 67  FPGGN---IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           F   N   +G  A+    +D+A  GA P   +    L +  P   L+     +   A A 
Sbjct: 75  FADVNPLTLGHKALAVNLSDLAACGARPVGFTLALSLPDADP-AWLQGFSQGLFALADAH 133

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
              +V GDT          L I     G  P           AGD + VSGTLGD    +
Sbjct: 134 NCPLVGGDTTRGP------LNICITVFGETPPGQALLRSGARAGDDIWVSGTLGDAALAL 187

Query: 184 --LNLREQLGLDGELVS--DCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
             L  R+QL  +   ++       TP     + + G+         G+   +        
Sbjct: 188 HCLWGRDQLPAEAFALARQRLEQPTPRAALGQALRGIATAAADVSDGLLGDLGHILERSH 247

Query: 240 CGIELSE-AALPVKPAVRGVCELLG-LDA------------LNFANEGKLVIAVERNAAE 285
            G EL    A+ +  A   +    G  D             L+  ++ +LV         
Sbjct: 248 VGAELEALYAINLLAARAYLTGASGTFDPNSQTDSTALRYVLSGGDDYELVFTAAPEHRL 307

Query: 286 QVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV 320
           QV AA      G     IG +V   GV +    G 
Sbjct: 308 QVQAA--GTHSGTPVTRIGRIVRDPGVTVKAPDGS 340


>UniRef50_A6FBC8 Thiamine monophosphate kinase n=1 Tax=Moritella sp. PE36
           RepID=A6FBC8_9GAMM
          Length = 346

 Score =  140 bits (354), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 63/318 (19%), Positives = 113/318 (35%), Gaps = 40/318 (12%)

Query: 21  SLFMEAFANPWLAEQEDQARL--DLAQL-VAEGDRLAFSTDSYVIDPLFFP---GGNIGK 74
            L  + F N  +   +    +  D A L V  G +L  +TD+ V    F       +I  
Sbjct: 7   DLIGQYFTNKSVPRDDVITGIGDDCAILSVPAGKQLVVTTDTMVSGIHFLSDANPTDIAH 66

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
             +    +D+A  G  P + S    L      E L A   S+ +     G++++ GDT  
Sbjct: 67  KLVAVNISDIAAMGGQPAWASLALTLP-SFDTEWLSAFSDSLHQQLHRYGVSLIGGDT-- 123

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNLREQLG 191
             +G +    +     G +            AGD++  SGT+GD  A    +++   +  
Sbjct: 124 -TKGNMT---LTLTLQGFVEQGKALPRHGAKAGDLIYCSGTIGDANAGLKLLIDANNRTD 179

Query: 192 LDGE--------------LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAA 237
           L  E              L++     T  + T + + G+         G+ + +     A
Sbjct: 180 LHPENSDEALLTKNDKDYLIARHQRPTARVSTGQALVGIANSCIDLSDGLASDLKHILKA 239

Query: 238 CG------CGIELSEAALPVKPAVRGVCE--LLGLDALNFANEGKLVIAVERNAAEQVLA 289
                       +  +ALP+  A++      L    AL   ++ +L+  V      Q+  
Sbjct: 240 SSRACGVALSANIELSALPLSTALQTYVSKALWPQYALAGGDDYELLFTVSAENKAQLED 299

Query: 290 ALHSHPLGKDAALIGEVV 307
            +  H L      IGE+V
Sbjct: 300 VMAEHDL--PYTHIGEIV 315


>UniRef50_C6V4B8 Thiamine-monophosphate kinase n=2 Tax=Neorickettsia
           RepID=C6V4B8_NEORI
          Length = 313

 Score =  140 bits (353), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 26/284 (9%)

Query: 51  DRLAFSTDSYVIDPLFFP---GGNIGKLAICGTANDVAVSGAIPRYLSCGFIL-EEGLPM 106
           D    + D  V    FFP     N+ K A+    +D+A  GA P     G +L E+    
Sbjct: 40  DDFVITKDLLVESIHFFPFAEPRNLAKKALRVNLSDLAAMGAEPVGYFLGLVLGEKHKSS 99

Query: 107 ETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTA 166
             L      + +     GI +  GDT +        L I+   +G   A           
Sbjct: 100 TWLNRFAEGLLDDQHCYGIKLFGGDTVIHSG----PLLISVTMIGK-KAEHVLSRSGAKR 154

Query: 167 GDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRG 225
           GD L +SG +GD    +L+ + +L  +        +  P +   RD I  V +  D + G
Sbjct: 155 GDELCISGPIGDSHLGLLSYQGELQENSYFRGKYDLPEPCLDVSRDIISSVTSCIDISDG 214

Query: 226 GVNAVVHEFAAACGCGIELSEAALPVKPAVRGVC---ELLGLDALNFANEGKLVIAVERN 282
            ++   H  A      I +    +P+    + V      +  + L   ++ +L+  V R 
Sbjct: 215 LLSEAQH-LAKNSAVSITIFFDKVPISDEAKSVLLKKPEIRKELLTAGDDYQLLFTVPRE 273

Query: 283 AAEQVLAALHSHPLGKDAALIGEVVERKG-VRLAGLYGVKRTLD 325
                      +P+ +   +IG V E  G VR+   +G +   D
Sbjct: 274 -----------NPVTRKYPVIGFVSEGMGEVRVLDSFGREIYFD 306


>UniRef50_Q3A8K1 Thiamine-monophosphate kinase n=2 Tax=Desulfuromonadales
           RepID=Q3A8K1_PELCD
          Length = 329

 Score =  140 bits (353), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 72/297 (24%), Positives = 114/297 (38%), Gaps = 21/297 (7%)

Query: 42  DLAQLVAEGDRLAFSTDSYVIDPLFF-----PGGNIGKLAICGTANDVAVSGAIPRYLSC 96
           D A L     +   +T   +I+ + F        ++G+ ++    +D+A  G  PR+L  
Sbjct: 32  DCAVLELPPGQRLLTTKDLLIEGVHFQRAWTDSRSLGRKSVSVNVSDIAAMGGRPRHLYL 91

Query: 97  GFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN 156
           G  +     +E L+  +    E   A G  +V GDT          L I+    G++ A 
Sbjct: 92  GLGVPADFSVEELQLFMDGFLEAVTAYGACLVGGDTCRSPG----PLLISVTAEGSVAAG 147

Query: 157 IHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVS---DCAVLTPLIQTLRDI 213
                     G ++ VSGTLGD    +  L +    D  L S   D      L Q L   
Sbjct: 148 REVRRAGAGIGQIIYVSGTLGDSALALQQLGKGEVPDSFLASRHHDPTARVALGQALAQA 207

Query: 214 PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP----VKPAVRGVCELLGLDALNF 269
               A+ D +  GV A +     A   G  L E+ LP     +  ++    LL L AL+ 
Sbjct: 208 GLATAMIDISD-GVLADLGHILKASSVGALLEESLLPLSGAFRAVLQHAPHLLQL-ALSG 265

Query: 270 ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE-RKGVRLAGLYGVKRTLD 325
             + +L+  V     E  + AL +  L      IG +    +G+RL    G  R  +
Sbjct: 266 GEDYELLFTVAPER-EAEVDAL-ARTLALPLTRIGVITSADEGLRLRAADGSLRPAE 320


>UniRef50_Q1N2P0 Thiamine monophosphate kinase n=1 Tax=Bermanella marisrubri
           RepID=Q1N2P0_9GAMM
          Length = 305

 Score =  139 bits (352), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 68/317 (21%), Positives = 108/317 (34%), Gaps = 38/317 (11%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQARL----DLAQLVAEGDR-LAFSTDSYVIDPLFFPG 69
           M +    +  + F +P L       R     D A ++ + +  L FS D+ V    F   
Sbjct: 1   MNEF--DMIKQYFQDPQLHFPHPNVRFGIGDDCASILPDENHELVFSMDTLVDGVHFLQT 58

Query: 70  G---NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
               +IG  A+C T +D+A   A P   +    + E      L+     +AE A+     
Sbjct: 59  SNSFDIGTRALCVTLSDLAAMAATPIGFTLALTIPEAHST-WLQGFSQGLAEIAQRFHCP 117

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL 186
           IV GDT            I     G +             GD + VSG LGD    +  +
Sbjct: 118 IVGGDTTRGPH-----CVITIQVHGQVKKGKALMRSGAKPGDKVFVSGDLGDGAGALSQV 172

Query: 187 REQLGLDGELVSDCAVLTPLIQTLRDI-PGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
            E       L        P I+  + I     +  D +  G+   +     A   G+ + 
Sbjct: 173 LENPLDSTGLAQRYFQPLPEIEFAQAIQSYATSGMDISD-GLLQDLEHICRASQVGMMID 231

Query: 246 EAALPVKPAV---RGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
             ++P+   +    G    +   AL   ++ +LV                    G     
Sbjct: 232 PESIPMSADLIDKVGYQRAMKF-ALTGGDDYRLVYTAP------------DCAHGIQ--- 275

Query: 303 IGEVV-ERKGVRLAGLY 318
           IGEVV E K V ++GL 
Sbjct: 276 IGEVVAEPKSVNVSGLD 292


>UniRef50_B2V6K1 Thiamine-monophosphate kinase n=3 Tax=Aquificales
           RepID=B2V6K1_SULSY
          Length = 314

 Score =  139 bits (352), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 56/311 (18%), Positives = 100/311 (32%), Gaps = 33/311 (10%)

Query: 18  LINSL--FMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPG----GN 71
           LI  L   +       L    D    D A +   G  + F+ D  V +  F  G     +
Sbjct: 12  LIERLNQILPIHDKDVLVGYGD----DCACVNINGKLILFTVDIQVENSHFLKGKIKPED 67

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G        +DV   G +PR+      L + L    ++ V   + E     G   + G 
Sbjct: 68  LGWKLATSNVSDVVACGGLPRWALLSLALPKDLEYSFIEKVYLGIKEAQDYYGFYTIGG- 126

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT----ILNLR 187
                  + +++ I+    G                  + +SG LG   A     +++ +
Sbjct: 127 ----NCSSSNQIMIDMTMAGETEK--FISRSAAKPNQKIYLSGNLGCSKAGLELILMDKQ 180

Query: 188 EQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           E    +  L++        I  +  I    A  D +  G+ + +   +      I + + 
Sbjct: 181 EYEDFEIALINKHYRPKARIDLIEKIKQASACIDISD-GLTSDLSHISKKSNVKIIIEKE 239

Query: 248 ALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
            L +   ++  C   G D L++             + E+   AL S     D   IG   
Sbjct: 240 KLKIDENLKKFCLKYGKDPLDYIL----------TSGEEYEVALISEK-DLDLIEIGYTE 288

Query: 308 ERKGVRLAGLY 318
           E  GV L    
Sbjct: 289 EGFGVFLKEGD 299


>UniRef50_C1ZKV1 Thiamine-monophosphate kinase n=1 Tax=Planctomyces limnophilus DSM
           3776 RepID=C1ZKV1_PLALI
          Length = 320

 Score =  139 bits (351), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 62/333 (18%), Positives = 113/333 (33%), Gaps = 44/333 (13%)

Query: 10  SGGQAMQQ----LINSLFMEAFAN--PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           +GG+   +    LI  +   A  +    L   +D A L       E      +TD  ++D
Sbjct: 4   TGGRMTFRPEFALIERIRKAAGGSSRVLLGIGDDAAGLG----SREDRETLVATD-MLLD 58

Query: 64  PLFFPGGN-----IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
            + F          G+ A+    +D+A  G           +           ++  + E
Sbjct: 59  GVHFVVEECGPYWAGRKALAVNLSDLAAMGGRCIASFVSIAIPRNWNAHEADELMRGVLE 118

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD 178
            A      +  GDT         +L IN A +G               GDV++VSG LG 
Sbjct: 119 LAAKWDCPVAGGDTNSWDG----RLVINVAVVGETIEATSIRRAGAQVGDVIVVSGALGG 174

Query: 179 HGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAAC 238
              +I      L  +  L         +   L  +  + ++ D +  G+++ +     A 
Sbjct: 175 ---SIYG--RHLKFEPRL--------DVAAELLKLAKLNSMIDLSD-GLSSDLWHILRAS 220

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLD-------ALNFANEGKLVIAVERNAAEQVLAAL 291
             G  L +  +PV   VR   +++ L        AL+   + +L+  +     E +    
Sbjct: 221 HAGAVLEQKRIPVHEDVRHHADVVNLSSPPALAHALHDGEDFELLFTLSPAQWETLR--- 277

Query: 292 HSHPLGKDAALIGEVVERKGVRLAGLYGVKRTL 324
            +  L      IG +V  +  R+    G  + L
Sbjct: 278 QNWKLPIALTKIGTIVSEEACRIVSETGESKEL 310


>UniRef50_C9LRA0 Thiamine-phosphate kinase n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LRA0_9FIRM
          Length = 329

 Score =  139 bits (351), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 61/303 (20%), Positives = 109/303 (35%), Gaps = 29/303 (9%)

Query: 32  LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVS 87
           L   +D A      +   G     STD+ V    F        + G        +D+A  
Sbjct: 31  LGTGDDGAVF----MTPCGYDEVISTDTMVEGIHFTKRTMSAADTGYHLCAVNFSDMAAM 86

Query: 88  GAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINT 147
           GA P        L   L +  +++    + E  R   + ++ GD      G+   + +  
Sbjct: 87  GAEPVSFVISAALPGDLSITWIESCYDGIRECCREYSVNLLGGD----ITGSKQGVILTG 142

Query: 148 AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVS-DCAVLTPL 206
             +G +P N          GD++ V+GTLGD  A +  L +    +  +++       P 
Sbjct: 143 TIVGIVPENQAVKRSGAKEGDIVFVTGTLGDSSAGLSILLDGKKEEYPMLAIRHQRPKPQ 202

Query: 207 IQTLRDI--PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGL 264
           I   R +   G  +L D +  G++  ++E  +A    IEL +  +P+   +       G 
Sbjct: 203 IDFGRILRESGASSLNDVSD-GLSREINEITSASRVTIELEKERIPLSDELCRWGRDCGK 261

Query: 265 DALNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE--RKGVRLAGLY 318
           D   FA     + +LV  + +   E +               IG V +  +  V L    
Sbjct: 262 DPFCFAINGGEDYELVGTISKKNWEYIKDI-------DGVTGIGHVTKAGKGQVFLKDKN 314

Query: 319 GVK 321
            +K
Sbjct: 315 SIK 317


>UniRef50_C6CVI9 Thiamine-monophosphate kinase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CVI9_PAESJ
          Length = 349

 Score =  139 bits (350), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 60/301 (19%), Positives = 109/301 (36%), Gaps = 31/301 (10%)

Query: 29  NPWLAEQEDQARLDLAQLVAEGDR-----LAFST--DSYVIDPLFFPGGNIGKLAICGTA 81
              L   +D A +D A  +   D      +A  T  ++   + +     +IG  A+    
Sbjct: 24  GVRLGIGDDAALVDPAAPINGVDSPYEYIMAMDTMVETVHFNEVTMSYEDIGYKALASNV 83

Query: 82  NDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVD 141
           +D+A  G +P        + + L  E +  +   +   A   G+A++ GDT    +    
Sbjct: 84  SDIAAMGGVPLQALVSVSVPKQLGPEPMHRLYDGLYACAEQYGVAVIGGDTTSSPQ---- 139

Query: 142 KLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNLRE-------QLG 191
            L +     GA+ A           GD ++++G +G   A    +L  RE          
Sbjct: 140 HLVVAVTVTGAVEAGKALRRSGAKPGDAVVLTGPVGKSAAGLHFLLAQRERGADALAGER 199

Query: 192 LDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
              +LV      +P ++    L       +L D +  G+ +   E A A G  + L E  
Sbjct: 200 AAAQLVQAHRRPSPSVRAGRLLLARGTCHSLNDVSD-GLASEAWEIAEASGLVVSLFEKH 258

Query: 249 LPVKPAVRGVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           LP   ++     + G+D L +      +  L+  +     +   A    H  G    +IG
Sbjct: 259 LPRSGSMAAYAGVAGIDPLEWMLYGGEDYVLLGTM--EQGDAAAAQAAFHAEGLPFYIIG 316

Query: 305 E 305
           E
Sbjct: 317 E 317


>UniRef50_UPI00003C83B8 thiamine monophosphate kinase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI00003C83B8
          Length = 322

 Score =  138 bits (349), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 57/296 (19%), Positives = 98/296 (33%), Gaps = 22/296 (7%)

Query: 33  AEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGTANDVAVSGA 89
             +    R D A +         STD    +     G      GK       +D+A    
Sbjct: 18  GSKNLDNRDDCAIIGFGNYYALLSTDLITRETHLPEGAEPFLAGKFFAAINLSDIAAMAG 77

Query: 90  IPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAG 149
           IP        +     +  L+     +        ++I+ GDTK                
Sbjct: 78  IPSGFLISLSVSPEYDISYLEEFYRGVRHELDKFNVSIIGGDTK-----EGSDFTAAGTI 132

Query: 150 MGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL----NLREQLGLDGELVSDCAVLTP 205
           +G     +      +  G  L+V+ +LG   A  +     +  +LG+   L  D      
Sbjct: 133 IGKQVPELIRRRSEIKPGQFLMVTNSLGSSAAGYIYYMYGINRELGIRKML--DVEPRIN 190

Query: 206 LIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD 265
               +    G K + D +  GV A +H+ +   G G +L    +P    V     +    
Sbjct: 191 EAIKIS-ASGAKFMMDLSD-GVYASIHQISTDFGVGFKLYGDKIPFDRDVEKAASISNFS 248

Query: 266 ----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGL 317
               AL+F  + +L+  VE+N+ E+ +AA+       +   IGE      V   G 
Sbjct: 249 VSDIALSFGGDYELMFTVEKNSLEEFMAAMSHEN--IEVHCIGETYNGDNVIYDGR 302


>UniRef50_C6QHP2 Thiamine-monophosphate kinase n=1 Tax=Hyphomicrobium denitrificans
           ATCC 51888 RepID=C6QHP2_9RHIZ
          Length = 341

 Score =  138 bits (348), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 68/335 (20%), Positives = 113/335 (33%), Gaps = 31/335 (9%)

Query: 20  NSLFMEAFANPWLAEQEDQARL-DLAQLV--AEGDRLAFSTDSYVIDPLFF---PGGNIG 73
            +  ++ +  P          L D A  +  A G  L FS+D  +    FF      +I 
Sbjct: 18  ETELIQTYLAPLAEGMAGAFGLTDDAAFLRPASGSDLVFSSDPIIAGVHFFHDDRPADIA 77

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A+   A+D+A  GA P        L E    + + A    +       G  ++ GDT 
Sbjct: 78  WKALACNASDMAAKGAAPVAYLLTLALPEAPERDWIAAFADGLRAAQSEFGCKLIGGDTD 137

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
           V        L I    +G++ A          AGD + VSGT+GD    +   R+     
Sbjct: 138 VTPG----PLSIGITIIGSVAAGAFIPRGGAKAGDHVFVSGTIGDAALGLALRRDPSQFS 193

Query: 194 GELVSDCAVLTPLIQTLRDIPG--------VKALRDATRGGVNAVVHEFAAACGCGIELS 245
                  A+L       +             ++  D +  G+   +   A A   GI + 
Sbjct: 194 TLTDDQRALLLDRYLRPKPRLALAGPVRSHARSALDVSD-GLIKDLRRLAGAS-LGIAVK 251

Query: 246 EAALPVKPAVRGVCELLGLDA------LNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
              +P+ P  R     L  +       L   ++ +L+IAV     E+ +    +   G  
Sbjct: 252 FDDIPLSPPARAA---LAANPNVRDSILAGGDDYELLIAVAPENIEKFVT--SAGESGIR 306

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
              IG +  +    +    GV   L  P  +   R
Sbjct: 307 VHDIGVLESKITTVVLDPSGVPIALRRPGYDHFSR 341


>UniRef50_D1AS58 Thiamin-monophosphate kinase n=5 Tax=Anaplasma RepID=D1AS58_ANACI
          Length = 349

 Score =  138 bits (348), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 54/301 (17%), Positives = 107/301 (35%), Gaps = 19/301 (6%)

Query: 24  MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGT 80
           +E +  P +         D  ++ +       + D  V    F    N   + K A+   
Sbjct: 40  IEKYIRPLMRSGFSTENDDAGKISSPNGSFIVTQDILVEGTHFLRHSNPTLLAKKALRVN 99

Query: 81  ANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAV 140
            +D+A  GA P     G  L +G+  E  +     + E  +   + ++ GDT     G  
Sbjct: 100 LSDLAAMGAQPYGYMLGMSLPQGVTEEWWEQFSNGLREDNKNYNVNLIGGDTTSNNTGT- 158

Query: 141 DKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG-ELVSD 199
             + I+   MG +P            GD L VSG +GD    ++  ++ +G +   L   
Sbjct: 159 --ITISITAMG-VPGMQSMTRSQAKVGDFLYVSGNIGDATLGLMAYQDLIGGEYFALKRR 215

Query: 200 CAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVC 259
             +  P I     I G+ +       G+   +         G  +    +P+  A +   
Sbjct: 216 YDLPEPRITLGSKICGIASACIDISDGLVQDIGHICRLSNVGASIHLNQIPMSDAAQ--- 272

Query: 260 ELLGLDA------LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           ++L  +        +  ++ +L      +   +++    +  LG     IG +V + GV 
Sbjct: 273 DVLRRNPELIERICSGGDDYELAFTSAESNHTKIMHI--AADLGVKVTTIGVIVRQPGVE 330

Query: 314 L 314
           +
Sbjct: 331 V 331


>UniRef50_Q1NMW0 Thiamine-monophosphate kinase n=2 Tax=delta proteobacterium MLMS-1
           RepID=Q1NMW0_9DELT
          Length = 337

 Score =  138 bits (347), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 62/293 (21%), Positives = 106/293 (36%), Gaps = 21/293 (7%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFF-----PGGNIGKLAICGTANDVAVSGAIPR 92
               D A   A+    + +T   +I+ + F     P   +G+ A+    +D+A  G  PR
Sbjct: 32  GIGDDCAAWQADPTACSLATTDTLIEGVHFDSSWHPPRLLGRKAVTVNISDIAAMGGTPR 91

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
           ++     L         + ++  + E   A G  ++ GDT         ++ +    +G 
Sbjct: 92  FVLLSLGLTGREEAAWREELLAGLVEATAAYGAHLIGGDTVHSPG----RVMLTVTVLGE 147

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDC-AVLTPLIQ--- 208
           +             GD L VSG LG   A +   R  LG +        A L P  Q   
Sbjct: 148 VAEAELCRRDGGRQGDSLWVSGPLGWAAAGLELCRRGLGTEERWQPLVKAHLNPDAQVAL 207

Query: 209 --TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
              L     V A++D +  G+   +   AAA G G E+    LP    ++        D 
Sbjct: 208 GRALARGRLVHAMQDLSD-GLATDLAHLAAASGQGAEVKAELLPQAELLQAAATHCEADP 266

Query: 267 LNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLA 315
             +      + +L+ +      +  +AAL           IG++V   GV L+
Sbjct: 267 TTWTIAGGEDYQLLFSAPPEH-DPAIAALSQRDKLPALHRIGQLVAGAGVFLS 318


>UniRef50_B8KML1 Putative thiamine-monophosphate kinase n=1 Tax=gamma
           proteobacterium NOR5-3 RepID=B8KML1_9GAMM
          Length = 366

 Score =  138 bits (347), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 65/334 (19%), Positives = 119/334 (35%), Gaps = 27/334 (8%)

Query: 16  QQLINSLFMEAFAN--PWLAEQEDQARLDLAQLVAE---GDRLAFSTDSYVIDPLF---- 66
           ++ I +  M+   +     +        D   L       +RL  +TD   +   +    
Sbjct: 18  ERFIKARIMDRIRSSVDKGSGLVGGLGHDAGVLRESLLPNERLLVNTDRSGVSKAYTLGL 77

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
             G  IG  A+    +D+  +G IP  +S   +L     ++ +  +V  + E      + 
Sbjct: 78  AGGECIGDFAVSHAVSDILATGGIPFAVSVAMLLPGSTSVKLVDEIVDGIVEACAEFDVT 137

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA-TILN 185
           I  GDTK       +KL +    +G    +      T   GD L+VSG LG     +I++
Sbjct: 138 ITGGDTK-----KAEKLSLVVTALGRASEDRLLFRDTPKVGDQLVVSGFLGSMLMGSIIH 192

Query: 186 LREQL--GLDGELVSDC----AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
            R      L  +LV +          L   +       A  D +  G+ +          
Sbjct: 193 KRHHKVSELIQKLVDEALVRQRPPYRLAMEMGAARIATACTDISD-GLPSACRNMVEKSN 251

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEG---KLVIAVERNAAEQVLAALHSHPL 296
            G+EL    +P+ PA+  + + L L  L  +  G   + +  + + +   +     S   
Sbjct: 252 LGVELFADNIPIHPALESLLKTLSLTPLQLSMAGGDWQFLYCMPKASIASLNRI--SDSC 309

Query: 297 GKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAE 330
           G    ++GEV    GV      G +R +     +
Sbjct: 310 GTPLTVVGEVTGASGVWTRSKCGRRRKVRAIEHD 343


>UniRef50_B4UJS8 Thiamine-monophosphate kinase n=7 Tax=Cystobacterineae
           RepID=B4UJS8_ANASK
          Length = 329

 Score =  138 bits (347), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 78/319 (24%), Positives = 112/319 (35%), Gaps = 27/319 (8%)

Query: 17  QLINSLFME---AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGG 70
           +LI         A A   L   +D A L        G+ LA + D+ V    F   F   
Sbjct: 16  ELIERFTRALPLAGAGVRLGPGDDTALL----APPPGEDLAATVDAVVEGVHFDARFTPE 71

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A+    +D+A  GA P +         G P E L+ V   +   ARA  IA+V G
Sbjct: 72  DVGWKALAVNLSDLASMGARPLWALVALAFPRGTPPERLEGVARGLGACARAHRIAVVGG 131

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
                      +L +    +GA+             GD+L+ SGT GD    +       
Sbjct: 132 -----NVSRASELSVTVTAVGAVRRGRALLRSGARPGDLLVASGTFGDAALGL-----AP 181

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
           G    LV       P +   R + GV         G+   +       G    L  AA+P
Sbjct: 182 GASAALVRRQRRPAPRLALGRALAGVARAAIDVSDGLVQDLGHLCDESGVAAVLEAAAVP 241

Query: 251 VKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
              A R     L  D     L    + +LV A+      + L A  +       A+IG V
Sbjct: 242 TSAAYRRAARSL-PDPLGPALGGGEDYELVAALPPARLARALRA--AARARVPLAVIGRV 298

Query: 307 VERKGVRLAGLYGVKRTLD 325
               GVR+ G  G +R   
Sbjct: 299 ERGSGVRILGADGAERPAP 317


>UniRef50_Q0BTF2 Thiamine-monophosphate kinase n=2 Tax=Acetobacteraceae
           RepID=Q0BTF2_GRABC
          Length = 331

 Score =  137 bits (345), Expect = 6e-31,   Method: Composition-based stats.
 Identities = 64/311 (20%), Positives = 110/311 (35%), Gaps = 19/311 (6%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---IGK 74
           +I        A   L   +D A L        G  L  + D+ V    + PG +   + +
Sbjct: 20  MIARYLAPLAAAGGLNLTDDAALLQ----PPPGLSLVLAADAMVEGVHYLPGTDPHLLAR 75

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPME-TLKAVVTSMAETARAAGIAIVTGDTK 133
             +    +D+A  GA P +      L  G        A    +AE     GI ++ GDT 
Sbjct: 76  KLLRVNLSDLAAMGAAPLHYLMTLALPRGTDPAPWFTAFTAGLAEDQGIFGITLLGGDTT 135

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
            ++  A     ++   +G +        Q     D + V+GT+GD    +L L E L   
Sbjct: 136 SIKGPA----CLSLTVIGTVEPGKAVRRQGACPDDEIWVTGTIGDGALGLLALTEGLADP 191

Query: 194 GELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
            + ++    L      L D   V+A  D +  G+   +     A G    +    +P+  
Sbjct: 192 DDFLAGRYHLPSPRLGLIDQSLVQAAADISD-GLLQDLGHLCTASGLDALVEADTVPLSD 250

Query: 254 AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV----ER 309
           A R          L+  ++ +LV+AV  +    +     +  LG     IG       ++
Sbjct: 251 AARRHMPEYLPLCLSGGDDYELVMAVSPSCTVPLRQ--RADSLGIPVQRIGRFHARSGQK 308

Query: 310 KGVRLAGLYGV 320
            GV +    G 
Sbjct: 309 PGVHVLASDGS 319


>UniRef50_UPI00016C3B48 thiamine-monophosphate kinase n=1 Tax=Gemmata obscuriglobus UQM
           2246 RepID=UPI00016C3B48
          Length = 303

 Score =  137 bits (345), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 61/292 (20%), Positives = 100/292 (34%), Gaps = 35/292 (11%)

Query: 25  EAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGT 80
            A +   L   +D      A L      L  +TD  +    F         +G+ A+   
Sbjct: 16  PAHSRVRLGPGDD-----CAALEPPARELLVTTDMLMDGTDFILSEVGARRVGRKAMAAN 70

Query: 81  ANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAV 140
            +D+A    +P   +    L      +  + +   + + A A  + IV GDT        
Sbjct: 71  LSDIAAMAGVPTAATVSLALPNSHGADLARELFLGLRDVADAFNVPIVGGDT----NSWA 126

Query: 141 DKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDC 200
             L ++   +G               GD + VSG LG    +IL              D 
Sbjct: 127 GSLVVSVTALGEATVRGPVRRGGARPGDWIFVSGPLGG---SILGH----------HLDF 173

Query: 201 AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCE 260
                    L ++  ++A+ D +  G++A ++       CG  L   A+P+  A R +  
Sbjct: 174 TPRVAEALQLHELVELRAMCDISD-GLSADLNHICEESRCGAVLDGDAVPITDAARELSR 232

Query: 261 LLGLDALNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE 308
             G   L  A     + +LV  V      ++LA     P     A IGE VE
Sbjct: 233 TSGRTPLQHALGDGEDFELVFTVSPEDGTKLLAR-RPFP---SLAKIGECVE 280


>UniRef50_Q9HHP1 Hydrogenase expression/formation protein n=1 Tax=Halobacterium
           salinarum RepID=Q9HHP1_HALSA
          Length = 231

 Score =  137 bits (345), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 59/210 (28%), Positives = 85/210 (40%), Gaps = 13/210 (6%)

Query: 116 MAETARAAGIAIVTGDTKVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSG 174
           MA      G+++VTG T    R  V   +I     MG             TAGD +L++ 
Sbjct: 1   MATECERLGVSVVTGHTA---RQDVSFPWIGGATAMGVGDPAEIVRPDGATAGDTVLMTH 57

Query: 175 TLGDHGATILNLR--EQLGLDGELVSDCAVLTPLIQTLRDIPG-----VKALRDATRGGV 227
           + G   A +      + L +  + V            + D        V A+ DAT  G+
Sbjct: 58  SPGAEVAGLFAALFGDHLDVADDTVERADARLEDTTVVGDACAAASAPVTAMHDATECGI 117

Query: 228 NAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQV 287
              + E A A G  I +S  A+PV   V  VC  LGLD    ++ G L++ V    A+  
Sbjct: 118 QGALVELATAAGVSISVSSDAVPVPEDVSAVCADLGLDPWQVSSRGTLLVTVPEAHADTA 177

Query: 288 LAALHSHPLGKDAALIGEVVERKGVRLAGL 317
           +AAL +       A IG V E  GV + G 
Sbjct: 178 MAALDARN--TPVAAIGTVSEGSGVTVDGT 205


>UniRef50_Q7NG75 Thiamine-monophosphate kinase n=1 Tax=Gloeobacter violaceus
           RepID=Q7NG75_GLOVI
          Length = 328

 Score =  136 bits (344), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 64/287 (22%), Positives = 105/287 (36%), Gaps = 23/287 (8%)

Query: 42  DLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
           D A +      L  +TD    D  F        ++G  +     +D+A  GA P  +  G
Sbjct: 32  DAAVVAPGSGALVATTDLLFEDVHFGDRTTGPFDVGWRSAAANLSDLAAMGAAPFGMLVG 91

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
             L  G  +E ++A        +   G  ++ GDT   +   V         +G +    
Sbjct: 92  LGLSPGTSVEWVEAFYEGFTACSAPVGALLLGGDTCRAKSRTV-----AVTALGTVDPRR 146

Query: 158 HWGAQTLTAGDVLLVSGTLG--DHGATILNLREQLGLDGELVSDC--------AVLTPLI 207
                    GD L+V+G LG    G  +L   E+    G  V +              + 
Sbjct: 147 ILRRNAARPGDALVVTGHLGASRAGLAVLLEAERYAHLGSPVREAVVAAHRRPKPRLEVP 206

Query: 208 QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA- 266
             +  + G  A  D T  G+   + +  A  GCG  +  A LP+  A   V     +   
Sbjct: 207 PLVFALSGRAAAMD-TSDGLTDAIAQVCAQSGCGAVVDLAVLPIDAATAQVAGKQAIAWA 265

Query: 267 LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           L    + +L+IA+E  AA Q++  L +  +G   A++G  V    V 
Sbjct: 266 LGGGEDYELLIALEPGAAVQLVERLAA--IGIGGAIVGRAVAGDRVV 310


>UniRef50_C7R8N3 Thiamine-monophosphate kinase n=1 Tax=Kangiella koreensis DSM 16069
           RepID=C7R8N3_KANKD
          Length = 323

 Score =  136 bits (344), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 61/313 (19%), Positives = 116/313 (37%), Gaps = 28/313 (8%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFP---GGNI 72
           +LI   F  +F+        +    D A L V +  +L  S D+ V    FF      +I
Sbjct: 5   ELIKEYF--SFSQSKSDTVVEGIGDDCAVLSVPDKRQLVTSVDTLVDGVHFFSDSDPADI 62

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
              ++    +D+A  GA P   +    L + +    LK+    + E +    I ++ GDT
Sbjct: 63  AYKSLAVNVSDLAAMGAKPLGFTLAIALPK-VDEVWLKSFSKGLQEASADFEIPLIGGDT 121

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I    +G++ A+     ++    D + V+G +GD  A  L L  +   
Sbjct: 122 TQGP------LTITVNVLGSVKADKAMLRKSAQLDDDIWVTGYVGDAAAA-LGLHGKAQS 174

Query: 193 DGELVSDCAVLTPLIQ-------TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
                ++  +L  L++         +      A  D + G +   +        C  ++ 
Sbjct: 175 SDLNEAESYLLQRLLRPNPPITFATKLAKLAHAAIDISDGLLAD-LGHILEQSQCSAKIK 233

Query: 246 EAALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
             +LP+   +      E     ALN  ++ +L    + +   ++L    +     +   I
Sbjct: 234 VGSLPLSEQLIQCVGLEQAREFALNGGDDYELCFTAKHSMRNKILNL--AEDFQVNVHRI 291

Query: 304 GEVVE--RKGVRL 314
           G +VE   +GV L
Sbjct: 292 GTIVEQSDEGVFL 304


>UniRef50_B1L7H6 Thiamine-monophosphate kinase n=1 Tax=Candidatus Korarchaeum
           cryptofilum OPF8 RepID=B1L7H6_KORCO
          Length = 320

 Score =  136 bits (343), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 70/327 (21%), Positives = 112/327 (34%), Gaps = 33/327 (10%)

Query: 16  QQLINSLFMEAFANPW--LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPG---G 70
           ++LI+ +      +P+  L    D    D +          F  D         PG    
Sbjct: 5   RELIDEIIGLVSEDPYGLLRLGRD----DASARRLNEGIYVFKMDMVSSSTDLLPGMSLR 60

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            + K  +    +DVA  GA P    C   L  G+  E   ++     E  R  G  +V G
Sbjct: 61  QLAKKCVVANFSDVASKGARPLLFMCSLGLPRGMRDEEFVSIFEGFEEAMRKYGTYLVGG 120

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           D      G  ++L I+    G +      G      GD+++ +G+ G       +L E L
Sbjct: 121 D-----LGESEELIISGFAFGRVE-GRLVGRGGSRPGDIVMTTGSFGLTWLGFKHLLEGL 174

Query: 191 GLDGELVSDC----AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
            L   L              ++    I         +  G+   + E + A G G  + E
Sbjct: 175 ELPEGLRRRALKSVYEPEARVEEGIIISNYATSTVDSSDGLYWSLKELSRASGNGFLIEE 234

Query: 247 AALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
             LP+   V      LG D    A +   E ++V  +      +V   L    LG +   
Sbjct: 235 --LPLDEEVGL---FLGGDSISAAFHGGEEYEIVFTLREEDVAKVRDEL--TVLGVEPIK 287

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHA 329
           IG VVE  G+RL         +++P  
Sbjct: 288 IGRVVEGGGIRLRA---GNELIEVPEG 311


>UniRef50_A3VRR7 Thiamine-monophosphate kinase n=1 Tax=Parvularcula bermudensis
           HTCC2503 RepID=A3VRR7_9PROT
          Length = 320

 Score =  136 bits (343), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 64/305 (20%), Positives = 122/305 (40%), Gaps = 14/305 (4%)

Query: 26  AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIGKLAICGTA 81
           +  + +LA    +  + L    A  + +  + D  ++D + F      G   + A+    
Sbjct: 5   SLIDRYLAPLAIEGAVGLQDDAALFEGMIITKD-LLVDGVHFRSCDGWGAAAQKALRVNI 63

Query: 82  NDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVD 141
           +D+   GA P   + G +  + +  E + A +  ++      G+ ++ GDT   +  +  
Sbjct: 64  SDLVACGARPAAFALGVVWPKAVTEEEIAAFMEGLSADCARYGLGLIGGDTTRHRADSG- 122

Query: 142 KLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCA 201
            L I+   +G               GDV++V+GT+G+    + +L  ++    E V    
Sbjct: 123 PLTISVTMVGPPAPEGPLRRSGAQVGDVVMVTGTIGEAVLGLKSLLGEIAPTSEGVEAYL 182

Query: 202 VLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCE 260
              P I  +  +     A  D + G +    H  A A G  + L  AA+P+ P+ R   E
Sbjct: 183 RPRPPIDLVDALARYAHAAIDISDGLLADATH-IAEASGVVLGLDAAAIPLSPSARAYAE 241

Query: 261 LLG---LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER-KGVRLAG 316
             G   L  L   ++ +++  V ++  + + AA  +         IGEV E   G  L G
Sbjct: 242 DSGDALLSLLGGGDDYQVIATVPQDNVDPLRAA--AATAQVPLTSIGEVREGAAGTVLRG 299

Query: 317 LYGVK 321
             G +
Sbjct: 300 GDGKE 304


>UniRef50_Q1QUD0 Thiamine-monophosphate kinase n=1 Tax=Chromohalobacter salexigens
           DSM 3043 RepID=Q1QUD0_CHRSD
          Length = 319

 Score =  136 bits (342), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 73/307 (23%), Positives = 114/307 (37%), Gaps = 22/307 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLF---FPGGNI 72
            +I   F    + P +         D A L  E G  LA S D+ V+D  F    P   I
Sbjct: 6   DIIARYFTTPDSEPPMPGVALGVGDDCALLSPEAGHELALSVDTSVVDVHFPGDAPPEAI 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA PR       L      + L+       E  R     ++ GD 
Sbjct: 66  GHRALAVALSDLAAMGARPRGCLMALTLS-HAEPDWLERFAHGFRELGRRTATPLIGGD- 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTL-GDHGATILNLREQLG 191
             V RG+   L I    +G +PA           G+ L V+G+L G H    +       
Sbjct: 124 --VTRGS---LSIGVTVIGDVPAGQALRRTGAAPGERLAVTGSLGGGHAGLRMWQAGGHD 178

Query: 192 LDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           L   L++     TP +   + +  + +       G+ A +     A G G  LS   LP+
Sbjct: 179 LADPLLAAYLTPTPQLAAGQALRDLASAGLDISDGLLADLGHLCRASGVGAVLSPDDLPL 238

Query: 252 KPAVRGVCELLGLD-----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
            P++      LG +     ALN  ++ +L+++V   A         +  +      IG V
Sbjct: 239 APSLDMT---LGREAALHAALNGGDDYQLLVSVPDAAWADAQQRCAACDVAL--TEIGRV 293

Query: 307 VERKGVR 313
               G+R
Sbjct: 294 TAEPGIR 300


>UniRef50_D1PUY6 Thiamine monophosphate kinase n=6 Tax=Prevotella RepID=D1PUY6_9BACT
          Length = 370

 Score =  135 bits (340), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 53/357 (14%), Positives = 107/357 (29%), Gaps = 68/357 (19%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTD----SYVIDPLFFPGGNIG 73
           LI+ +  +   N   A        D A +      +  +TD        D  +     +G
Sbjct: 11  LIDHITKDIQLNN--ASSIFGIGDDCAVMHYPNTEVLITTDMLMEGIHFDLTYVTMQELG 68

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A     +D+      PR ++    + +   +E ++A    +        I IV GDT 
Sbjct: 69  YKAAMENISDIFAMNGTPRQMTVSMAIGKRFKVEDIEAFYKGLRSACDKWSIDIVGGDTT 128

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
                +   L I+   +G                D++ V+G LG     +  L  +  + 
Sbjct: 129 S----SYTGLAISITCIGEARKEDIVYRNGAKETDLVCVTGDLGAAYMGLQLLEREKEVY 184

Query: 194 GELVSDCAVLTPLIQTLRDIPGV------------------------------------- 216
            + + D        Q   +   V                                     
Sbjct: 185 YQQIDDINRKIKEAQKAGNEEAVKHFQEQGSHIANFQPDFAGKEYLLERQLKPEARGDMI 244

Query: 217 ----------KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD- 265
                      A+ D +  G+++ +        CG  + E  +P+      + E L ++ 
Sbjct: 245 QLLREHNIRPTAMMDISD-GLSSELLHICKRSNCGCRIYEKNIPIDYQTAIMAEELNINV 303

Query: 266 ---ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK-GVRLAGLY 318
              A+N   + +L+        +++   L    + +    IG + + + GVRL    
Sbjct: 304 TTAAMNGGEDYELLFTCPIGDHDKLQD-LEEAGVKQ----IGYITKPELGVRLISRD 355


>UniRef50_Q6MP56 Thiamine-monophosphate kinase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MP56_BDEBA
          Length = 318

 Score =  135 bits (340), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 51/261 (19%), Positives = 93/261 (35%), Gaps = 26/261 (9%)

Query: 66  FFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGI 125
           +F   ++G  ++    +D+A  GA+P +      L + L    L      M   A    +
Sbjct: 60  YFSAFDLGYKSLAVNLSDIAAMGALPHFAQVSLALPKKLNESWLDDFYKGMTSLADDHHM 119

Query: 126 AIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN 185
            +V GD         D+L ++ +  G+         +    GD+LL SG LG     +  
Sbjct: 120 QVVGGDLAASP----DRLVVDVSVHGSCEN--PLTRKGAKPGDLLLCSGPLGLSFTGMTA 173

Query: 186 LREQLGLDGELVSDCAVLTPLIQTLRDIPG----VKALRDATRGGVNAVVHEFAAACGCG 241
           L+++L    +         P +  +  +      + AL D + G VN  +         G
Sbjct: 174 LQKKLSGFDDAKERHLRPKPRLDLVASLQKQHTRIHALMDCSDGLVNDALQL--RPPNGG 231

Query: 242 IELSEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
             L    LP+ P    +   L L+     L    + +L++AV     E            
Sbjct: 232 FHLFAENLPLHPDSESLAVDLHLNPQDFVLWGGEDYELLMAVHPEDYE----------YF 281

Query: 298 KDAALIGEVVERKGVRLAGLY 318
            +  +IG+  E   V ++   
Sbjct: 282 PEWKMIGQFTEDPRVFVSHPD 302


>UniRef50_A5UMR0 Thiamine monphosphate kinase, ThiL n=3 Tax=Methanobrevibacter
           smithii RepID=A5UMR0_METS3
          Length = 306

 Score =  134 bits (339), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 53/318 (16%), Positives = 106/318 (33%), Gaps = 45/318 (14%)

Query: 20  NSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG----NIGKL 75
             L     AN      +D A   +A           ST   +I    FP       +G  
Sbjct: 11  KELIKYILANCKTITPDDTAVTPIANTN------LISTCDMLIQSKHFPENMSYFQMGFK 64

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVV 135
           ++    +D+A  GA P        L +   ++  K ++  + +     GI ++ GDT   
Sbjct: 65  SVTVNVSDLAAMGATPLGFLLSIALPKDFEVDDFKQIIKGVLKACEYYGICLIGGDT--- 121

Query: 136 QRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE 195
                 ++ I+   +G     +         GD+++++G +G              L+ +
Sbjct: 122 --NEASEIIISGTALGLCDNPLMKNTS--EKGDLVVLTGKIGLAAL-------GFNLEND 170

Query: 196 LVSDCAVLTPLIQTLRDIPGV-----KALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
            +     L P I  +++   +      +  D T  G+ + ++E       G  + E  L 
Sbjct: 171 NIYTKKALEP-IAKIKEGINIKNSGGTSATDITD-GLASELYEMKRE-DIGFMIYEDKLD 227

Query: 251 VKPAVRGVCEL----LGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           +    + +            L+   + +LV  + +            H L     +IGEV
Sbjct: 228 ISGEFKSLAAELNLNYLDLLLHVGEDFELVFTINKKNL---------HKLNFKYLVIGEV 278

Query: 307 VERKGVRLAGLYGVKRTL 324
            + K V +       R +
Sbjct: 279 TDSKKVEIRLSDSTVRQI 296


>UniRef50_Q8TXQ3 Thiamine monophosphate kinase n=1 Tax=Methanopyrus kandleri
           RepID=Q8TXQ3_METKA
          Length = 309

 Score =  134 bits (339), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 60/284 (21%), Positives = 106/284 (37%), Gaps = 23/284 (8%)

Query: 33  AEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPR 92
           A  +D A L    +V      A +   +V  P      ++G   +    +DV   G  P 
Sbjct: 38  AGDDDAAVLPDGTVVNFD---AMTRSRHV--PKELRDRDLGWKFVASVVSDVGAMGGEPS 92

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
           +      L++ + +E L   V  ++E  R  G++++ GD         ++L ++   +G 
Sbjct: 93  FFGFSVCLDDEVDVEQL---VLGISEGLREFGVSLIGGDVV-----EGEELVLSGTCLGK 144

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRD 212
           +             GDV+ V+G LG   A +  +   +  +  L    A   P ++   +
Sbjct: 145 L-KGEPLLMSNARPGDVVAVTGPLGGPNAFVRAILNGMEPEETLYERFARPRPPVEVGVE 203

Query: 213 IP--GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFA 270
           +   G +A       G+ A     A   G  IE+    +PV   V  V +   +D ++ A
Sbjct: 204 LARGGYRAAVTDISDGLLAEAEAIARRSGVAIEIHTWKVPVDEGVEEVAQEFDVDPVDLA 263

Query: 271 NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
            EG           E V+              IG V E +GVR+
Sbjct: 264 LEGGEDYEFLICGPEDVVKEFG-------LTTIGRVTEGEGVRI 300


>UniRef50_UPI0001C16452 Thiamine-monophosphate kinase n=2 Tax=Nostocaceae
           RepID=UPI0001C16452
          Length = 349

 Score =  134 bits (338), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 58/320 (18%), Positives = 106/320 (33%), Gaps = 42/320 (13%)

Query: 24  MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTD----SYVIDPLFFPGGNIGKLAICG 79
           +++F  P +   +D A L           L  +TD          L     + G  A   
Sbjct: 23  LQSFCPPHII-GDDGAVL----PTKPAHHLVVTTDMLVDGVHFSNLTTSPKDAGWRAATA 77

Query: 80  TANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGA 139
             +D+A  GA P  ++    L   L +  ++ +   M++  +     IV GD        
Sbjct: 78  NLSDLAAMGASPLGITVALGLPGDLAVNWVEQLYQGMSDCLQKYHTPIVGGDIVRSPVTT 137

Query: 140 VDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE-------QLGL 192
                I     G +  ++     T   G+ ++++G  G   A +  L         +   
Sbjct: 138 -----IGITAFGEVSPDLIIRRCTAQVGNAIVITGMHGASRAGLELLLHPQTGENLKEEE 192

Query: 193 DGELVSDCAVLTPLIQTL--------------RDIPGVKALRDATRGGVNAVVHEFAAAC 238
              L+       P +  +               D   V      +  G+   + +   A 
Sbjct: 193 KQALIRFHQRPNPRLDVIYVLHEILISGLKPRGDSSPVTLSGMDSSDGLADAILQICRAS 252

Query: 239 GCGIELSEAALPVKPAV-RGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
             G  L +  +P+ P     +  L  LD AL    + +LV+ +    A+ ++  L     
Sbjct: 253 QVGAVLHQDKIPLVPISNNWLTPLRWLDYALYGGEDFELVLCLPPTIAKALVLKL----- 307

Query: 297 GKDAALIGEVVERKGVRLAG 316
           G  AA+IGE+     V L  
Sbjct: 308 GSGAAIIGEITSGDQVILQS 327


>UniRef50_Q3ZZF3 Thiamine-monophosphate kinase n=5 Tax=Dehalococcoides
           RepID=Q3ZZF3_DEHSC
          Length = 336

 Score =  134 bits (338), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 59/313 (18%), Positives = 100/313 (31%), Gaps = 28/313 (8%)

Query: 28  ANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTAND 83
             P           D A  + +G +L  + DS + +  F        ++G  A+    +D
Sbjct: 26  NTPARENLILDIGDDAAVFLPQGYQLV-TVDSLIENVHFNRSMLNWADLGYKALAINMSD 84

Query: 84  VAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKL 143
           +A  G +P+Y      L     + ++     +M   A      I+ GDT           
Sbjct: 85  IAAMGGLPQYAVVNIDLPPDTLVSSVTDCYNAMYSLANKYQTVIIAGDTNQSS------- 137

Query: 144 FIN--TAGMGAIP-ANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE----L 196
            IN     +G+    +         AG  + V+G LG+  A +  L  Q  +  E     
Sbjct: 138 IINLAITLLGSAENPSCLLTRNAAQAGQKIAVTGYLGNAAAGLDMLLNQTEVTDESRRIF 197

Query: 197 VSDCAVLTPLI--QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
                   P I    L    GV    D +  G+   +            +    LP+ P+
Sbjct: 198 YRSFYRPKPRINEARLLVKEGVHCCIDISD-GLVTDLGHILRQSRVSARIELDKLPLHPS 256

Query: 255 VR-GVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           +R          AL    + +L+        EQ+     S        +IGE++  K   
Sbjct: 257 LRLSYPLQAQNMALYGGEDYELLFTASAKVIEQI-----SVQSHIPVTIIGEIIPGKPEE 311

Query: 314 LAGLYGVKRTLDL 326
           L  +    R L  
Sbjct: 312 LKLVDKDGRALQP 324


>UniRef50_C0B9V8 Putative uncharacterized protein n=1 Tax=Coprococcus comes ATCC
           27758 RepID=C0B9V8_9FIRM
          Length = 337

 Score =  134 bits (338), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 54/329 (16%), Positives = 114/329 (34%), Gaps = 23/329 (6%)

Query: 12  GQAMQQLINSLFMEAFAN--PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPG 69
           G+  Q +     ++   N    +                  +R+  +TD  +        
Sbjct: 13  GRVSQTVYRRSVLKQIQNNIEGIDFLRPSQEETCYIADESEERITIATDVSLA----GNE 68

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            ++G  AI    + +A  GA    +S   +L        LKA++  ++E  +  G+ +  
Sbjct: 69  KDLGVFAIAQAVDQLASRGARAYGISVRIMLPTFAYESRLKAMMVEISEICKEKGLRVFF 128

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA-------- 181
            D + V    +    ++    G         +++  AG+ +++   +G  G         
Sbjct: 129 ADAQSV--NGIQTSIVHVTAHGEAKKEQLLASRSAKAGEEIVLVKWIGMEGTLRIIREEG 186

Query: 182 TILNLREQLGLDGELVS-DCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
             L  R   G   +L      + +     +    GV A+     GG+ A + + A   G 
Sbjct: 187 AALAERFAPGFLNKLEDMRDEIFSDRAMEIAGRNGVSAMHPIGEGGILAALWDMAEGAGI 246

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G+ +    + V+     VCE+  L+     + G +++   +   E++   L     G  A
Sbjct: 247 GLSVEMKKMTVRQETIEVCEVFHLNPYQLTSTGAVLMVTPK--GEELKERLKRE--GIPA 302

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHA 329
            +IG   E     + G  G ++ +     
Sbjct: 303 EIIGHTTEGNERIIWG--GGEKKISRQTG 329


>UniRef50_D1VW68 Thiamine-phosphate kinase n=2 Tax=Prevotella RepID=D1VW68_9BACT
          Length = 375

 Score =  134 bits (338), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 56/325 (17%), Positives = 101/325 (31%), Gaps = 67/325 (20%)

Query: 38  QARLDLAQLVAEGDRLAFSTD----SYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRY 93
               D A +      +  +TD        D  +    ++G  A     +DV      PR 
Sbjct: 30  GVGDDCAVMHYPHSEVLTTTDMLMEGVHFDLTYIDLQHLGYKAAMVNISDVFAMNGTPRQ 89

Query: 94  LSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAI 153
           +     +++   +E ++A    +        + IV GDT   + G    + I+   +G  
Sbjct: 90  MLVSLAIDKRFSVEDIEAFYNGLRMACNKWKVDIVGGDTTSSRTG----VAISITCIGEA 145

Query: 154 PANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ------------------------ 189
            +            D++ VSG LG     ++ L  +                        
Sbjct: 146 KSEEIVYRNGAKDTDLICVSGDLGAAYMGLMLLEREKSVYYKQVDEIRTKILKAKEQKNQ 205

Query: 190 ---------LGLDGELVSDCA-------------VLTPLIQTLRDIP-GVKALRDATRGG 226
                    L   G    D A                 +I+TLR       A+ D +  G
Sbjct: 206 ALVTKLTHDLNSLGNFQPDFAGKEYLLQRQLQTEARGDIIETLRAAHIHPTAMIDISD-G 264

Query: 227 VNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERN 282
           +++ +        CG  + E  LP+      + E L L+    ALN   + +L+  V   
Sbjct: 265 LSSELLHICKESNCGCRIYEKNLPIDYQTAVMAEELNLNVTTCALNGGEDYELLFTVPIG 324

Query: 283 AAEQVLAALHSHPLGKDAALIGEVV 307
             E++          +   LIG + 
Sbjct: 325 DHEKIQTL-------EGIKLIGHIT 342


>UniRef50_D2LH51 Thiamine-monophosphate kinase n=1 Tax=Rhodomicrobium vannielii ATCC
           17100 RepID=D2LH51_RHOVA
          Length = 333

 Score =  134 bits (337), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 70/310 (22%), Positives = 109/310 (35%), Gaps = 25/310 (8%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNI 72
             LI  +      +P      D A   L+ L   G  L  +TD+ V    FF     G+ 
Sbjct: 7   NALIAEILAPLATHPGAFGLSDDAAH-LSDLPPNG--LVMTTDALVAGVHFFENDDPGDA 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
              A+    +D+A   A P        L      +  +A    +A    A G++++ GDT
Sbjct: 64  AYKAVAVNVSDLAAKAAKPFAYLLTLALPAAPTEDWARAFAEGLARAQAAFGVSLIGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
            V  RG     +++   +G  PA           GDVL V+GTLGD    +         
Sbjct: 124 -VTARG---PWWLSVTALGDAPA-RPLVRGGGRPGDVLYVTGTLGDAALGLKMRLGLDDF 178

Query: 193 DGELVSD------CAVLTPLIQTLR---DIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
            G L +D         L P  +            A  D +  G+   +     A G    
Sbjct: 179 AGALSADETEHLARRYLYPEPRVSLRPALAAHASAAMDLSD-GLALDLTRLCTASGVTAS 237

Query: 244 LSEAALPVKPAVR---GVCELLGLDALNFANEGKLVIAVERNAAEQVLA-ALHSHPLGKD 299
           +  +ALP+  A R     C  L    +   ++ +++ AV  + A   LA    +   G  
Sbjct: 238 VDASALPLSEAARSAVAACPALIEAIIAGGDDYEILAAVPPDTASHSLAFEATARDAGCP 297

Query: 300 AALIGEVVER 309
              IG + E 
Sbjct: 298 VFRIGTLAEG 307


>UniRef50_B6BWK7 Thiamine-monophosphate kinase n=1 Tax=beta proteobacterium KB13
           RepID=B6BWK7_9PROT
          Length = 316

 Score =  134 bits (337), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 54/308 (17%), Positives = 109/308 (35%), Gaps = 28/308 (9%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---IG 73
            LI   F     +  L   +D A + L       + +A S D+  I   F    +   +G
Sbjct: 5   DLIKKYFNFTSKHALLGIGDDAALIPL----NNNEFMAISMDTLNIGHHFTEDSDPYYLG 60

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             ++    +D+   G  PRY      L + L +  +      +   A+   I IV GDT 
Sbjct: 61  WKSLAVNVSDIVSMGGQPRYALLSISL-KNLDVNWIGKFTKGIKACAKKYNIEIVGGDTN 119

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI----LNLREQ 189
              +G+     I+ A MG + +            D + V+  +G          L  + +
Sbjct: 120 ---KGSTS---ISIAIMGNVSSKNVLKRSGAIPEDEIWVTNEVGYAALHFNQHSLLPKYK 173

Query: 190 LGLDGELVSDCAV----LTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIEL 244
             +   L   C        P ++ ++D    + +  D +  G+   +     +   G ++
Sbjct: 174 KSISNCLKKRCQEEFFKPQPPLEFIQDTKSMINSAIDLSD-GLVGDLKHILNSSSVGAKI 232

Query: 245 SEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
               +P+    RG  +     A+    + ++++        ++   L  H L    A+IG
Sbjct: 233 EINEIPMHKWFRGNNQY--ELAMCGGEDYQILMTASHKHHNKIQNLLKKHSL--KGAMIG 288

Query: 305 EVVERKGV 312
            + + K +
Sbjct: 289 IITKDKKI 296


>UniRef50_A0NME7 Thiamine-monophosphate kinase n=2 Tax=Labrenzia RepID=A0NME7_9RHOB
          Length = 332

 Score =  134 bits (337), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 65/310 (20%), Positives = 108/310 (34%), Gaps = 38/310 (12%)

Query: 17  QLINSLFMEAFANPW-LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNI 72
           +LI   F     +P  L   +D A L       +G  L  + D    D  FF       I
Sbjct: 10  ELIRRFFAPLAKDPGSLGLTDDAAVL----TPHQGYDLVLTKDVLAADIHFFAEDAPEAI 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
              A+    +D+A  GA PR    G  L     ++ L+     +A    A    +  GDT
Sbjct: 66  AAKALRVNLSDLAAKGARPRGYLMGLSLPSDWTVDWLERFCNGLAADQAAYDFHLYGGDT 125

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL------ 186
                 + + L ++   +G +             GD+L V+GT+GD  A +         
Sbjct: 126 VR----SGNGLQVSITAIGEVETGKAVRRSGAQPGDLLFVTGTIGDAAAGLQARLNPDFC 181

Query: 187 --------REQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAAC 238
                    E   LD  L+      T L   + D     A  D + G +    H  A A 
Sbjct: 182 RDHDLTESEEGHILDRYLLP--RPCTRLAGAVADY--ASAAMDVSDGLIADCAH-MAKAS 236

Query: 239 GCGIELSEAALPVKPAVRG----VCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSH 294
              + +    +P+  A+        E      LN  ++ ++++AV +  ++ +     +H
Sbjct: 237 ALELTIDLDLVPLSQALTHLKIKAPEDFAR-CLNGGDDYEILMAVPQERSDTLRRV--AH 293

Query: 295 PLGKDAALIG 304
             G     IG
Sbjct: 294 LAGCPVTQIG 303


>UniRef50_A2BKY5 Predicted thiamine-monophosphate kinase n=1 Tax=Hyperthermus
           butylicus DSM 5456 RepID=A2BKY5_HYPBU
          Length = 326

 Score =  133 bits (334), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 73/312 (23%), Positives = 122/312 (39%), Gaps = 30/312 (9%)

Query: 13  QAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPG--- 69
           +A+++LI  +    +  P L   +D A +           L    D   +  L+ P    
Sbjct: 10  EAVKRLIEEILAGQWRCPSLGPGDDAACVG-----GGFQNLILKIDGGSLASLWAPWMEP 64

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            +IG  A+   A+D+   GA P   +    L+ G  +ETLK +V   AE A+A G  ++ 
Sbjct: 65  ADIGWQAVAAAASDLVAKGAKPLAFAVSLGLDPGEDIETLKGIVRGAAEAAQAHGAWLLG 124

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLV-SGTLGDHGATILNL-- 186
           GDT           +I+ A +G     +       + GD + V +G +G  G  + +L  
Sbjct: 125 GDTNSCSNCG----WIDVAAVGLAEKPVGL---QASPGDTVYVTTGRIGLAGLVLDSLAK 177

Query: 187 ---REQLGLDGELVSDCAVLTPLIQ--TLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
              RE +       S+ A     ++   L     + A  D +  G+   + + A A    
Sbjct: 178 GRWREAMEAYPRAFSEFARPRARLEFVELAGTGCITAATD-SSDGLAYSLGKIAEAAH-- 234

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGK---LVIAVERNAAEQVLAALHSHPLGK 298
             +    +PV+P      E  G+D L  A  G     VI   R   E+++    +  LG 
Sbjct: 235 ALVELENIPVEPEALRYAEEYGVDPLELALYGGQEYEVIFAVRGGCEKLVEE-RAATLGL 293

Query: 299 DAALIGEVVERK 310
             A IG + E  
Sbjct: 294 AVARIGRLREGP 305


>UniRef50_C7JHE3 Thiamine monophosphate kinase n=8 Tax=Acetobacter pasteurianus
           RepID=C7JHE3_ACEP3
          Length = 329

 Score =  133 bits (334), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 58/308 (18%), Positives = 104/308 (33%), Gaps = 15/308 (4%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGK 74
            I   F        L  ++D A         EG  L  + D  V +  F P      IG+
Sbjct: 18  FIRQHFSALAGAAALELRDDAAVF----TPPEGRELVIAADGMVENVHFLPDDPPETIGR 73

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
             +    +D+A  G+ P      F     +  + +      +       G+ ++ GDT  
Sbjct: 74  KLLRCNLSDLAAMGSRPEGWLLTFARPPHITEQWVAQFCKGLKADQAQFGLQLLGGDTTS 133

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
            +      L ++   +G++        Q   AGD L V+GT+GD    +  L+ ++    
Sbjct: 134 TRG----PLVLSLTILGSVLPGQAIRRQGAQAGDGLWVTGTIGDGALGLRALQGEIADPS 189

Query: 195 ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
             ++    L      L       A  D + G +    H  A      + +   A+P+  A
Sbjct: 190 GYLAQRYRLPQPRIGLPLYGLASAAMDISDGLLQDAGH-LARESELHVTIHADAVPLSDA 248

Query: 255 VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLA--ALHSHPLGKDAALIGEVVERK-G 311
            R          L   ++ +++ AV       +L+   L +         IGE  +   G
Sbjct: 249 ARQTGPKWLETCLTGGDDYEILFAVPAQHEAALLSKGTLDTVCGPVKVTRIGEFTQASTG 308

Query: 312 VRLAGLYG 319
           V +    G
Sbjct: 309 VTVLDSAG 316


>UniRef50_A1K2S2 Thiamine-phosphate kinase n=9 Tax=cellular organisms
           RepID=A1K2S2_AZOSB
          Length = 336

 Score =  132 bits (333), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 71/316 (22%), Positives = 104/316 (32%), Gaps = 22/316 (6%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---IGK 74
           LI   F     +  LA  +D A L        G  LA S D  V    FFP  +   +G 
Sbjct: 25  LIQRHFSRPCGHTALAGGDDAALLHPRP----GMELAVSADMLVAGTHFFPDADPHDLGW 80

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
             +    +D+A  GA PR+      L        + A        A   G+ +  GDT  
Sbjct: 81  KTLAVNVSDLAAMGADPRWALLSLAL-PAADDAWIAAFADGFYACAERFGVDLAGGDTTR 139

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
                   L ++   +G +P           AGD + VSG  G     +  LR       
Sbjct: 140 GP------LTLSVTILGEVPRGQALTRAGANAGDDIWVSGQPGLAALGLEMLRGTFAPTA 193

Query: 195 ELVSDCAVLT---PLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           +     A L    P +   + + G+ +       G+   +        CG  L E ALP+
Sbjct: 194 DGERCLAALHRPQPRVALGQALRGLASAALDISDGLLGDLGHILVQSRCGATLHEDALPL 253

Query: 252 KP--AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
               A      L     L   ++ +L+      AA   + AL    L      IG + + 
Sbjct: 254 AALYATGASPALARRCLLAGGDDYELLFCAPP-AARAAITALGPA-LALPLTRIGTLSDA 311

Query: 310 KG-VRLAGLYGVKRTL 324
            G V L    G    L
Sbjct: 312 PGTVALRSADGTLTAL 327


>UniRef50_Q2GJY6 Thiamine-monophosphate kinase n=1 Tax=Anaplasma phagocytophilum HZ
           RepID=Q2GJY6_ANAPZ
          Length = 318

 Score =  132 bits (333), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 59/298 (19%), Positives = 101/298 (33%), Gaps = 13/298 (4%)

Query: 24  MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---IGKLAICGT 80
           +E +  P L         D A + +       + D  V +  F    +   + K A+   
Sbjct: 7   IEKYIRPLLRSGFASENDDAAHVSSPTSSFIMTKDVLVENVHFLNHSDPFLLAKKALRVN 66

Query: 81  ANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAV 140
            +D+A  GA P     G  L + +  E  K+    + E      I +  GDT        
Sbjct: 67  LSDIASMGATPHSYLLGLSLPKFIDEEWWKSFCAGLQEDNSIFSIKLTGGDT---TNNLA 123

Query: 141 DKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-GLDGELVSD 199
           D + I+   +G IP+           GD L VSGT+GD    +L   ++L G    L   
Sbjct: 124 DIIVISITALG-IPSANILTRSNAKVGDYLYVSGTIGDAALGLLAYNKKLIGEFSYLKQR 182

Query: 200 CAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVC 259
             +  P +     I  V +       G+   +       G G  L    +P+        
Sbjct: 183 YDLPQPRVMLGTSISNVASACIDVSDGLLQDIGLLCKLSGVGANLYAYEVPLSHEAAAAI 242

Query: 260 ---ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
                L  + L   ++ +L   V      +V     +  +      IG +   +G+R+
Sbjct: 243 MQNHDLLENVLAGGDDYELAFTVPPKYCPEVEQI--ATNIKIPVKRIGVITREQGIRV 298


>UniRef50_B5EQ44 Thiamine-monophosphate kinase n=3 Tax=Acidithiobacillus
           RepID=B5EQ44_ACIF5
          Length = 340

 Score =  132 bits (333), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 64/292 (21%), Positives = 107/292 (36%), Gaps = 32/292 (10%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGKLAICGTANDVAVSGAIPRYL 94
               D A L   G +L  + D+ V    FFP     ++   A+    +D+A  GA  R+ 
Sbjct: 26  GIGDDAAWLDPAGRQLVATMDTLVAGRHFFPEVSPEDLAWKALAVNLSDLAAMGAEARWC 85

Query: 95  SCGFILE---EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMG 151
                L    EG   E L+A  T  +  A    + +V GDT          L ++   +G
Sbjct: 86  LLSLALPWRAEGYG-EWLEAFATGWSALADRHDVTLVGGDTVATDG----PLTLSITALG 140

Query: 152 AIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQT-- 209
                +    +    GDV+ V+GTLGD  A +     + G +   V   A     ++   
Sbjct: 141 LSGHGVM-RREAARPGDVIWVTGTLGDAAAALDLALVERGQERRAVPCSAPRRDALEARR 199

Query: 210 LRDIP-----------GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGV 258
           LR  P           GV    D + G +   +     A G   +++  ALP+ P +  +
Sbjct: 200 LRPTPRLEFGAAALAGGVLCAVDCSDGFLAD-LGHILKASGVHAQVALDALPLSPDLADL 258

Query: 259 C----ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
                E L    L   ++ +L++      +  +  A  S  L      +G +
Sbjct: 259 ARTDPERLQRWPLTGGDDYELILCAAPALSTALQEAARS--LSLRLTAVGSI 308


>UniRef50_B3DWZ3 Thiamine monophosphate kinase n=1 Tax=Methylacidiphilum infernorum
           V4 RepID=B3DWZ3_METI4
          Length = 319

 Score =  132 bits (332), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 58/295 (19%), Positives = 101/295 (34%), Gaps = 32/295 (10%)

Query: 38  QARLDLAQLVAEGDRL--AFSTDSYVIDPLF---FPGGNIGKLAICGTANDVAVSGAIPR 92
               D A +   G+ L   F  D+ V +  F    P   IG+ A+    +D+A  G  P 
Sbjct: 52  GIGEDCAVVQGRGNDLYYLFKVDATVENVHFEAGTPPELIGRKALARALSDIAAMGGEPL 111

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
           Y   G  + +   +E +K +   +   A+A  + I+ G+T V +     +LF+  +  G 
Sbjct: 112 YALVGIGISKDQKIEKIKKIYEGIRSLAQAFDLLIIGGETTVSE-----QLFLVVSLWGK 166

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRD 212
                       T GD L V+G LG                              + L +
Sbjct: 167 TEGYKPVLRSGATDGDGLFVTGVLGGS------------FQSGHHLVFMPRIKEGKWLAN 214

Query: 213 IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANE 272
               KA+ D +  G+   +   A A   G E+   A+P++             AL    +
Sbjct: 215 GRWAKAMMDISD-GLAKDLPRMAKASSIGFEIDFDAIPIRGGYTIKA------ALTEGED 267

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLP 327
            +L+ +V +    +++    S P       IG   +R        +        P
Sbjct: 268 YELLFSVAKEKENKLI---QSWPFDVPLKKIGFFSQRGKRNFPDEFRGFDHFQEP 319


>UniRef50_C6HZ14 Thiamine-monophosphate kinase n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HZ14_9BACT
          Length = 335

 Score =  131 bits (331), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 73/307 (23%), Positives = 109/307 (35%), Gaps = 32/307 (10%)

Query: 38  QARLDLAQLV-AEGDRLAFSTDSYVIDPLFFPGGNI-----GKLAICGTANDVAVSGAIP 91
               D A +    G  L  +TDS   + + F    I     G+  +    +D+   G  P
Sbjct: 30  GIGDDCALITQPPGCDLLVTTDSQR-EGVHFRWEWIDPFSVGRRLVAVNVSDIVSKGGRP 88

Query: 92  RYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMG 151
            +      L  G P   +  V   +AE +R  G+ +  GD      G    + +    +G
Sbjct: 89  AFSVVAAGLPPGDPPGRIAEVYRGIAEESRYYGVVVAGGDISRDPGG----MSLVMTLLG 144

Query: 152 AIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLI---- 207
            IP     G   L  GD L + G  G   + +L+L +         +  A  TP      
Sbjct: 145 WIPPGTFVGRGGLAPGDCLYLVGRPGRARSGLLSLEKDQDETLFSEARAAFRTPRALLRE 204

Query: 208 -QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
              L   PGV ++ D T  G+   + E A A    I++ E  +PV   VR   E LG + 
Sbjct: 205 GPLLASFPGVVSMTD-TSDGLGRSLWELARASRVTIKVEE--IPVSKEVRKWAEALGENP 261

Query: 267 ----LNFANEGKLVIAVERNAAEQVL-----AALHSHPLGKDAALIGEVVER--KGVRLA 315
                    +  L++ V     E  L       L   P G    LIG+V ER    +   
Sbjct: 262 GELVWTGGEDYDLLVGVSFREEEAFLKWARTDLLEGSPEGL--FLIGQVGERGDPEIIFG 319

Query: 316 GLYGVKR 322
              G K 
Sbjct: 320 SGTGGKE 326


>UniRef50_C0EUP9 Putative uncharacterized protein n=1 Tax=Eubacterium hallii DSM
           3353 RepID=C0EUP9_9FIRM
          Length = 373

 Score =  131 bits (330), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 64/303 (21%), Positives = 113/303 (37%), Gaps = 46/303 (15%)

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
             K A+ G  N +  +GA P+ +S   ++ E    + LKA++  +        I +++G 
Sbjct: 69  AAKRAVYGAVNSMLAAGAAPKAISLSILMPEEAEEKQLKALIKEIDSLCMQENILVLSGH 128

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHW---------------------------GAQTL 164
           T V     V  L ++   MG+   N                                + +
Sbjct: 129 TAVSPY--VSTLILSVTAMGSTTENRKDITANKGSITRNKESILVSKESIADSKGNTKQI 186

Query: 165 TAGDV---LLVSGTLGDHGATILNLREQLGLD----GELVSDCAVLTP-----LIQTLRD 212
             G+    L+V+GT+G  GA +L       L+       V     L        ++ +  
Sbjct: 187 AVGNADLDLVVAGTVGREGAAMLAAEYAKRLEERYAPSYVEAAKHLFDDGSMTAVEDILQ 246

Query: 213 IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANE 272
              V ++ D   GG+ A + E AAA   G+ +    +P+K     VCE   L+     + 
Sbjct: 247 EKEVVSVHDVREGGIFAALWEMAAAANVGLSIDLKNIPIKQHTIEVCEYFNLNPYMLRSG 306

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           G L++A    A  +++  L     G  AA+IG+       RL       R L+ P  +  
Sbjct: 307 GTLLLACANGA--RIVEQLQKA--GVAAAVIGQTTSGND-RLIRYDDEARFLEPPKMDEY 361

Query: 333 PRI 335
            ++
Sbjct: 362 YKV 364


>UniRef50_B2SNW6 Thiamine-monophosphate kinase n=21 Tax=Gammaproteobacteria
           RepID=B2SNW6_XANOP
          Length = 365

 Score =  131 bits (330), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 61/316 (19%), Positives = 103/316 (32%), Gaps = 34/316 (10%)

Query: 21  SLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY---VIDPLFFPGGNIGKLAI 77
            + + A A+  L   +D A L        G++LA +TD+    V  P      ++G   +
Sbjct: 52  RVRIAARADVPLGIGDDAALLH----PPAGEQLAITTDTLNAGVHFPQETRADDLGWKTL 107

Query: 78  CGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQR 137
               +D+A  GA PR+ +    L        +          A A  I +V GDT     
Sbjct: 108 AVNLSDLAAMGAQPRWCTLSLSLP-HDDAAWVDLFADGFFALADAHDIVLVGGDTTRGP- 165

Query: 138 GAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL------- 190
                L      +G++P +          GD + V+G  G+  A +   +          
Sbjct: 166 -----LSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGEAAAALALWQAGQLDVTCAA 220

Query: 191 --GLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCG---IEL 244
              L  +  S      P +Q    + G   A  D + G +   +       G G      
Sbjct: 221 ADPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISDGLLAD-LGHLCDRSGVGAQLALA 279

Query: 245 SEAALPVKPAVR-GVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           +  A+P         C       L   ++ +L           V  A+    +   A  I
Sbjct: 280 ALPAMPRSAGTSVAQCPGWQ---LGGGDDYELCFTAAPQHRAAVAQAMEFAEVA--ATRI 334

Query: 304 GEVVERKGVRLAGLYG 319
           G++V   GV +    G
Sbjct: 335 GQIVATPGVVVHDADG 350


>UniRef50_C0GR51 Thiamine-monophosphate kinase n=1 Tax=Desulfonatronospira
           thiodismutans ASO3-1 RepID=C0GR51_9DELT
          Length = 315

 Score =  131 bits (329), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 79/315 (25%), Positives = 117/315 (37%), Gaps = 35/315 (11%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNI 72
           +++NSLF     +  +   +D A L           L  S+D ++ D  F    F   +I
Sbjct: 10  EIVNSLFPREHPHMVVGRGDDCAVLKCPA------SLCMSSDLFLEDVHFRTRYFTPEDI 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P   +   I    L  E  +++++SMAE      +A+  GD 
Sbjct: 64  GHKALAVNLSDLAAGGARPLGFNLNLIWPVYLDEEFCRSMLSSMAELGAKFKLALTGGDL 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ--- 189
                     L +     G  PA           GDVL V G  G     +  L E    
Sbjct: 124 SF-----GKSLGLAVCIWGKSPARQML-RGKAEPGDVLFVVGKAGLAACGLSLLEENDPG 177

Query: 190 LGLDGELVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
           L    E V+      PL+   Q L  I  VK L D +  G+   +  F    G G+E+  
Sbjct: 178 LDRYPECVAQHLRPRPLVREGQVLAGIEEVKGLMDVSD-GLARDLPRFCRR-GTGVEICS 235

Query: 247 AALPVKPAVRGVCELLGLDALNFA----NEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
               V P V   C   GLD L  A     +  L+ A  R   + V   +       D   
Sbjct: 236 D-FRVHPEVAFFCRDRGLDPLATALKGGEDYALLGACTRKGWDTVKKKI------LDCRR 288

Query: 303 IGEVVERKGVRLAGL 317
           +G V ++ G+ L   
Sbjct: 289 LGTVTDKPGIFLQDR 303


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A6VPG0 Hydrogenase expression/formation protein HypE n=...   344   3e-93
UniRef50_C1F4L5 Hydrogenase expression/formation protein HypE n=...   338   2e-91
UniRef50_C6PIR8 Hydrogenase expression/formation protein HypE n=...   325   2e-87
UniRef50_C1DUF0 Hydrogenase expression/formation protein HypE n=...   325   2e-87
UniRef50_A4XJQ3 Hydrogenase expression/formation protein HypE n=...   323   6e-87
UniRef50_Q58089 Putative hydrogenase expression/formation protei...   319   7e-86
UniRef50_P40599 Hydrogenase expression/formation protein hypE n=...   312   9e-84
UniRef50_B8D1S4 Hydrogenase expression/formation protein HypE n=...   312   1e-83
UniRef50_Q0HUQ3 Hydrogenase expression/formation protein HypE n=...   308   1e-82
UniRef50_A8ZNR3 Hydrogenase expression/formation protein HypE n=...   308   2e-82
UniRef50_C6PPZ0 Hydrogenase expression/formation protein HypE n=...   307   4e-82
UniRef50_P31906 Hydrogenase expression/formation protein hypE n=...   303   5e-81
UniRef50_B7JZ80 Hydrogenase expression/formation protein HypE n=...   303   6e-81
UniRef50_B2TM78 Hydrogenase expression/formation protein HypE n=...   301   2e-80
UniRef50_C5ZXL6 Hydrogenase expression/formation protein HypE n=...   301   2e-80
UniRef50_B9KGD0 Hydrogenase expression/formation protein HypE n=...   301   3e-80
UniRef50_B0TWC9 Hydrogenase expression/formation protein HypE n=...   300   5e-80
UniRef50_Q39ZF9 Hydrogenase expression/formation protein HypE n=...   300   5e-80
UniRef50_B0TCN4 Hydrogenase expression/formation protein hype n=...   299   1e-79
UniRef50_B4U670 Hydrogenase expression/formation protein HypE n=...   297   3e-79
UniRef50_D2ATM4 Hydrogenase maturation factor-like protein n=35 ...   296   6e-79
UniRef50_B2UW48 Hydrogenase expression/formation protein n=12 Ta...   295   2e-78
UniRef50_A4CGN3 Hydrogenase expression/formation protein HypE n=...   293   4e-78
UniRef50_B7JF80 Hydrogenase expression/formation protein HypE n=...   292   9e-78
UniRef50_A6LXR5 Hydrogenase expression/formation protein HypE n=...   292   1e-77
UniRef50_P31905 Hydrogenase expression/formation protein hypE n=...   292   1e-77
UniRef50_A4YFA3 Hydrogenase expression/formation protein HypE n=...   290   3e-77
UniRef50_C3XF65 Hydrogenase expression/formation protein n=3 Tax...   289   7e-77
UniRef50_A7I1Q2 Hydrogenase expression/formation protein HypE n=...   287   3e-76
UniRef50_C9LR03 Hydrogenase expression/formation protein HypE n=...   287   5e-76
UniRef50_D1BLS0 Hydrogenase expression/formation protein HypE n=...   287   5e-76
UniRef50_UPI0001C42969 hydrogenase expression/formation protein ...   286   7e-76
UniRef50_A8A9S1 Hydrogenase expression/formation protein HypE n=...   285   1e-75
UniRef50_B5YJH9 Hydrogenase expression/formation protein HypE n=...   282   2e-74
UniRef50_C1SLC8 Hydrogenase expression/formation protein HypE n=...   281   2e-74
UniRef50_C7NVH7 Hydrogenase expression/formation protein HypE n=...   281   2e-74
UniRef50_D2LQB8 Hydrogenase expression/formation protein HypE n=...   280   4e-74
UniRef50_B4S328 Hydrogenase expression/formation protein HypE n=...   277   3e-73
UniRef50_Q8NKU8 Membrane-bound NiFe hydrogenase n=1 Tax=Acidianu...   277   5e-73
UniRef50_A7H7N3 Hydrogenase expression/formation protein HypE n=...   276   6e-73
UniRef50_C8PGA7 Hydrogenase expression/formation protein HypE n=...   275   2e-72
UniRef50_A6C222 Hydrogenase expression/formation protein HypE n=...   274   2e-72
UniRef50_C9KK60 Hydrogenase expression/formation protein HypE n=...   272   1e-71
UniRef50_B2KBC5 Hydrogenase expression/formation protein HypE n=...   268   2e-70
UniRef50_D1VJK8 Hydrogenase expression/formation protein HypE n=...   265   1e-69
UniRef50_B5Y920 Hydrogenase expression/formation protein HypE n=...   264   3e-69
UniRef50_B6YVE6 HypE n=9 Tax=Thermococcaceae RepID=B6YVE6_THEON       264   4e-69
UniRef50_A4TCL4 Hydrogenase expression/formation protein HypE n=...   262   1e-68
UniRef50_D1Y5N1 Hydrogenase expression/formation protein HypE n=...   261   2e-68
UniRef50_C1TK23 Hydrogenase expression/formation protein HypE n=...   261   4e-68
UniRef50_D0SP02 Thiamine-monophosphate kinase n=1 Tax=Acinetobac...   255   2e-66
UniRef50_C7G8J7 Hydrogenase maturation factor n=4 Tax=Clostridia...   254   3e-66
UniRef50_C5CEU2 Hydrogenase expression/formation protein HypE n=...   253   4e-66
UniRef50_B1YBW5 Hydrogenase expression/formation protein HypE n=...   251   2e-65
UniRef50_A9KBN8 Thiamine-monophosphate kinase n=5 Tax=Coxiella b...   251   2e-65
UniRef50_D1A5C3 Hydrogenase expression/formation protein HypE n=...   250   6e-65
UniRef50_Q5ZXK3 Thiamine monophosphate kinase (AIR synthase) n=6...   248   3e-64
UniRef50_B0VPT8 Thiamin-monophosphate kinase n=18 Tax=Moraxellac...   247   4e-64
UniRef50_C9RAP1 Thiamine-monophosphate kinase n=1 Tax=Ammonifex ...   246   1e-63
UniRef50_A3DKG6 Hydrogenase expression/formation protein HypE n=...   244   3e-63
UniRef50_A4XL04 AIR synthase related protein domain protein n=2 ...   244   4e-63
UniRef50_A1HSU1 Thiamine-monophosphate kinase n=1 Tax=Thermosinu...   243   7e-63
UniRef50_Q57190 Thiamine-monophosphate kinase n=279 Tax=Gammapro...   243   9e-63
UniRef50_B5FBG0 Thiamine-monophosphate kinase n=7 Tax=Vibrionace...   243   9e-63
UniRef50_A6W2L4 Thiamine-monophosphate kinase n=2 Tax=Marinomona...   242   1e-62
UniRef50_D0KYD5 Thiamine-monophosphate kinase n=1 Tax=Halothioba...   241   2e-62
UniRef50_B8D3R7 Hydrogenase expression/formation protein HypE n=...   241   2e-62
UniRef50_B7R791 AIR synthase related protein, C-terminal domain ...   240   7e-62
UniRef50_A8MLK1 AIR synthase related protein domain protein n=3 ...   239   1e-61
UniRef50_Q3II30 Thiamin-monophosphate kinase n=3 Tax=Alteromonad...   239   1e-61
UniRef50_A8ZNV6 Hydrogenase expression/formation protein HypE n=...   238   2e-61
UniRef50_A5EUI7 Hydrogenase expression/formation protein n=4 Tax...   238   2e-61
UniRef50_A3Z0T5 Hydrogenase expression/formation protein; HypE n...   238   2e-61
UniRef50_Q15W96 Thiamine-monophosphate kinase n=2 Tax=Alteromona...   237   3e-61
UniRef50_A8PLC8 Thiamine-monophosphate kinase n=2 Tax=Gammaprote...   237   4e-61
UniRef50_A1S0T2 AIR synthase related protein domain protein n=2 ...   236   7e-61
UniRef50_C0ZK37 Thiamin-monophosphate kinase n=1 Tax=Brevibacill...   235   1e-60
UniRef50_C9L525 Hydrogenase maturation factor n=1 Tax=Blautia ha...   235   2e-60
UniRef50_A0M637 Thiamine-monophosphate kinase n=43 Tax=Bacteroid...   235   2e-60
UniRef50_B8I2N9 AIR synthase related protein domain protein n=6 ...   233   6e-60
UniRef50_A4SVD0 Thiamine-monophosphate kinase n=1 Tax=Polynucleo...   233   7e-60
UniRef50_Q65TX9 ThiL protein n=4 Tax=Pasteurellaceae RepID=Q65TX...   233   8e-60
UniRef50_A0L3Z7 Thiamine-monophosphate kinase n=1 Tax=Magnetococ...   232   1e-59
UniRef50_B0KA39 AIR synthase related protein domain protein n=10...   232   1e-59
UniRef50_B3PBC5 Thiamine-monophosphate kinase n=1 Tax=Cellvibrio...   232   2e-59
UniRef50_Q5FNA0 Thiamin-monophosphate kinase n=1 Tax=Gluconobact...   231   2e-59
UniRef50_D2RDT5 Hydrogenase expression/formation protein HypE n=...   230   8e-59
UniRef50_A4J8J0 Thiamine-monophosphate kinase n=1 Tax=Desulfotom...   229   1e-58
UniRef50_A5N2W0 HypE n=8 Tax=Clostridium RepID=A5N2W0_CLOK5           228   2e-58
UniRef50_Q2RKM3 AIR synthase related protein-like n=1 Tax=Moorel...   228   2e-58
UniRef50_O05514 Thiamine-monophosphate kinase n=5 Tax=Bacillus R...   228   3e-58
UniRef50_C4LAD9 Thiamine-monophosphate kinase n=1 Tax=Tolumonas ...   228   3e-58
UniRef50_Q8K9A5 Thiamine-monophosphate kinase n=4 Tax=Buchnera a...   227   5e-58
UniRef50_C9YEU1 Thiamine-monophosphate kinase n=1 Tax=Curvibacte...   227   5e-58
UniRef50_Q0K6Z2 Thiamine monophosphate kinase n=114 Tax=Proteoba...   226   6e-58
UniRef50_D1C275 Thiamine-monophosphate kinase n=1 Tax=Sphaerobac...   226   6e-58
UniRef50_C7R8N3 Thiamine-monophosphate kinase n=1 Tax=Kangiella ...   226   6e-58
UniRef50_Q5QVE6 Thiamine monophosphate kinase n=2 Tax=Idiomarina...   226   7e-58
UniRef50_Q1IHF6 Thiamine-monophosphate kinase n=1 Tax=Candidatus...   226   1e-57
UniRef50_Q5FH10 Thiamine-monophosphate kinase n=4 Tax=canis grou...   225   1e-57
UniRef50_Q46DN9 Thiamin-monophosphate kinase n=4 Tax=Methanosarc...   225   2e-57
UniRef50_A7BRC9 Thiamine-monophosphate kinase n=1 Tax=Beggiatoa ...   225   2e-57
UniRef50_C0CMS4 Putative uncharacterized protein n=2 Tax=Clostri...   225   2e-57
UniRef50_D1VUU5 Hydrogenase maturation factor n=1 Tax=Peptoniphi...   224   3e-57
UniRef50_O27447 Probable thiamine-monophosphate kinase n=1 Tax=M...   224   3e-57
UniRef50_C5A3X6 Thiamine monophosphate kinase (ThiL) n=4 Tax=The...   224   3e-57
UniRef50_C8WRZ3 Thiamine-monophosphate kinase n=2 Tax=Alicycloba...   224   4e-57
UniRef50_C7JHE3 Thiamine monophosphate kinase n=8 Tax=Acetobacte...   223   5e-57
UniRef50_Q0ABQ2 Thiamine-monophosphate kinase n=3 Tax=Gammaprote...   223   6e-57
UniRef50_C3N301 AIR synthase related protein domain protein n=9 ...   223   8e-57
UniRef50_Q9V1N8 Probable thiamine-monophosphate kinase n=3 Tax=P...   223   8e-57
UniRef50_B8GHF5 AIR synthase related protein domain protein n=1 ...   223   8e-57
UniRef50_D1BMW6 Thiamine-monophosphate kinase n=3 Tax=Veillonell...   222   1e-56
UniRef50_A1AS86 Thiamine-monophosphate kinase n=9 Tax=Desulfurom...   222   1e-56
UniRef50_Q0W120 Putative thiamine monophosphate kinase n=2 Tax=E...   222   1e-56
UniRef50_Q6AKX6 Related to thiamine-monophosphate kinase (ThiL) ...   222   1e-56
UniRef50_C0GCU5 Thiamine-monophosphate kinase n=1 Tax=Dethiobact...   222   2e-56
UniRef50_B8D020 AIR synthase related protein domain protein n=1 ...   222   2e-56
UniRef50_Q3AE31 Thiamine-monophosphate kinase n=1 Tax=Carboxydot...   222   2e-56
UniRef50_C6X363 Thiamine-monophosphate kinase n=6 Tax=Bacteroide...   221   2e-56
UniRef50_C6VU01 Thiamine-monophosphate kinase n=25 Tax=Bacteria ...   221   3e-56
UniRef50_D1R9A7 Putative uncharacterized protein n=1 Tax=Parachl...   221   3e-56
UniRef50_Q8ESJ0 Thiamine monophosphate kinase n=1 Tax=Oceanobaci...   220   6e-56
UniRef50_A6CFS7 Thiamine-monophosphate kinase n=1 Tax=Planctomyc...   220   7e-56
UniRef50_B0TDV9 Thiamine-monophosphate kinase n=1 Tax=Heliobacte...   220   7e-56
UniRef50_B3QYZ8 Thiamine-monophosphate kinase n=1 Tax=Chloroherp...   220   8e-56
UniRef50_B0MTR2 Putative uncharacterized protein n=1 Tax=Alistip...   220   9e-56
UniRef50_B9KXI5 Thiamine-monophosphate kinase n=1 Tax=Thermomicr...   219   9e-56
UniRef50_Q1Q1A8 Similar to thiamine monophosphate kinase n=1 Tax...   219   1e-55
UniRef50_B4WXS9 Thiamine-monophosphate kinase n=1 Tax=Alcanivora...   219   1e-55
UniRef50_A1SWW7 Thiamine-monophosphate kinase n=2 Tax=Psychromon...   219   1e-55
UniRef50_B7JUY6 Thiamine-monophosphate kinase n=4 Tax=Cyanobacte...   219   1e-55
UniRef50_Q2RJB8 Thiamine-monophosphate kinase n=1 Tax=Moorella t...   218   2e-55
UniRef50_D2M233 Thiamine-monophosphate kinase n=1 Tax=Bacillus c...   218   2e-55
UniRef50_Q31FT3 Thiamine-monophosphate kinase n=1 Tax=Thiomicros...   218   2e-55
UniRef50_A6FBC8 Thiamine monophosphate kinase n=1 Tax=Moritella ...   218   2e-55
UniRef50_Q97BE7 Hydrogenase expression formation protein HypE n=...   217   4e-55
UniRef50_B4U7Q4 Thiamine-monophosphate kinase n=3 Tax=Aquificace...   217   4e-55
UniRef50_Q2GJY6 Thiamine-monophosphate kinase n=1 Tax=Anaplasma ...   217   5e-55
UniRef50_Q6MP56 Thiamine-monophosphate kinase n=1 Tax=Bdellovibr...   216   6e-55
UniRef50_D2QDU8 Thiamine-monophosphate kinase n=1 Tax=Spirosoma ...   216   7e-55
UniRef50_A1WVF9 Thiamine-monophosphate kinase n=2 Tax=Ectothiorh...   216   8e-55
UniRef50_A1AW74 Thiamine-monophosphate kinase n=2 Tax=sulfur-oxi...   216   9e-55
UniRef50_Q3ZZF3 Thiamine-monophosphate kinase n=5 Tax=Dehalococc...   216   1e-54
UniRef50_D0MD26 Thiamine-monophosphate kinase n=1 Tax=Rhodotherm...   215   1e-54
UniRef50_Q607V1 Thiamine-monophosphate kinase n=1 Tax=Methylococ...   215   2e-54
UniRef50_B9XDK5 Thiamine-monophosphate kinase n=1 Tax=bacterium ...   215   2e-54
UniRef50_C3K2R7 Thiamine-monophosphate kinase n=3 Tax=Gammaprote...   215   2e-54
UniRef50_D1PUY6 Thiamine monophosphate kinase n=6 Tax=Prevotella...   215   2e-54
UniRef50_Q2JTF1 Thiamine-monophosphate kinase n=11 Tax=Cyanobact...   215   2e-54
UniRef50_B1I671 Thiamine-monophosphate kinase n=1 Tax=Candidatus...   215   2e-54
UniRef50_B9KYQ7 Hydrogenase expression/formation n=2 Tax=Thermom...   215   2e-54
UniRef50_B7V7Q7 Thiamine monophosphate kinase n=11 Tax=Gammaprot...   215   2e-54
UniRef50_C5BS83 Thiamine-phosphate kinase n=1 Tax=Teredinibacter...   215   2e-54
UniRef50_B4RQH6 Thiamine monophosphate kinase n=28 Tax=Neisseria...   215   2e-54
UniRef50_C8R1R1 Thiamine-monophosphate kinase n=1 Tax=Desulfuriv...   214   3e-54
UniRef50_B6YUV4 HypE n=3 Tax=Thermococcus RepID=B6YUV4_THEON          214   4e-54
UniRef50_A0LIX8 Thiamine-monophosphate kinase n=1 Tax=Syntrophob...   214   4e-54
UniRef50_B5Y6B6 Hydrogenase expression/formation protein HypE n=...   214   5e-54
UniRef50_Q2RZV6 Thiamine-monophosphate kinase n=1 Tax=Salinibact...   213   5e-54
UniRef50_B9ZS01 Thiamine-monophosphate kinase n=1 Tax=Thioalkali...   213   8e-54
UniRef50_Q1N2P0 Thiamine monophosphate kinase n=1 Tax=Bermanella...   213   1e-53
UniRef50_D1J9H7 Thiamine-monophosphate kinase n=1 Tax=uncultured...   213   1e-53
UniRef50_UPI0001C16452 Thiamine-monophosphate kinase n=2 Tax=Nos...   212   1e-53
UniRef50_D1AS58 Thiamin-monophosphate kinase n=5 Tax=Anaplasma R...   212   2e-53
UniRef50_Q0BTF2 Thiamine-monophosphate kinase n=2 Tax=Acetobacte...   212   2e-53
UniRef50_B0KL72 Thiamine-monophosphate kinase n=13 Tax=Pseudomon...   212   2e-53
UniRef50_Q1YU39 Thiamine-monophosphate kinase n=1 Tax=gamma prot...   211   2e-53
UniRef50_Q3ARA0 Thiamine-monophosphate kinase n=11 Tax=Chlorobia...   211   2e-53
UniRef50_B6BWK7 Thiamine-monophosphate kinase n=1 Tax=beta prote...   211   2e-53
UniRef50_D2MI54 Thiamine-monophosphate kinase (Fragment) n=1 Tax...   211   4e-53
UniRef50_A8MDD6 AIR synthase related protein domain protein n=1 ...   210   4e-53
UniRef50_Q21F21 Thiamine-monophosphate kinase n=1 Tax=Saccharoph...   210   6e-53
UniRef50_C0QQC1 Thiamine-monophosphate kinase n=2 Tax=Hydrogenot...   210   6e-53
UniRef50_A8VUM5 Beta-lactamase domain protein n=1 Tax=Bacillus s...   210   6e-53
UniRef50_UPI0000E87BC8 Thiamine-monophosphate kinase n=1 Tax=Met...   210   7e-53
UniRef50_B6YTL7 Thiamine monophosphate kinase n=2 Tax=Thermococc...   210   7e-53
UniRef50_C7NS45 AIR synthase related protein domain protein n=1 ...   209   8e-53
UniRef50_A3DLS7 AIR synthase related protein domain protein n=1 ...   209   9e-53
UniRef50_A0NME7 Thiamine-monophosphate kinase n=2 Tax=Labrenzia ...   209   1e-52
UniRef50_A4YFC4 AIR synthase related protein domain protein n=3 ...   209   1e-52
UniRef50_Q2S9S1 Thiamine-monophosphate kinase n=1 Tax=Hahella ch...   209   1e-52
UniRef50_Q8D289 ThiL protein n=2 Tax=cellular organisms RepID=Q8...   209   1e-52
UniRef50_Q3A8K1 Thiamine-monophosphate kinase n=2 Tax=Desulfurom...   209   1e-52
UniRef50_C9LRA0 Thiamine-phosphate kinase n=1 Tax=Dialister invi...   209   1e-52
UniRef50_D1C5Z5 AIR synthase related protein domain protein n=7 ...   208   2e-52
UniRef50_B5JUN1 Thiamine-monophosphate kinase n=1 Tax=gamma prot...   208   3e-52
UniRef50_C1ZKV1 Thiamine-monophosphate kinase n=1 Tax=Planctomyc...   208   3e-52
UniRef50_Q5WJP9 Thiamine-monophosphate kinase n=3 Tax=Bacillus R...   208   3e-52
UniRef50_B2SNW6 Thiamine-monophosphate kinase n=21 Tax=Gammaprot...   208   3e-52
UniRef50_A5WHT2 Thiamine-monophosphate kinase n=4 Tax=Gammaprote...   206   7e-52
UniRef50_D1VW68 Thiamine-phosphate kinase n=2 Tax=Prevotella Rep...   206   7e-52
UniRef50_C6V4B8 Thiamine-monophosphate kinase n=2 Tax=Neorickett...   206   8e-52
UniRef50_Q1NMW0 Thiamine-monophosphate kinase n=2 Tax=delta prot...   205   2e-51
UniRef50_D1CF57 Thiamine-monophosphate kinase n=1 Tax=Thermobacu...   204   3e-51
UniRef50_B2V6K1 Thiamine-monophosphate kinase n=3 Tax=Aquificale...   204   3e-51
UniRef50_Q54757 Thiamine-monophosphate kinase n=9 Tax=Cyanobacte...   204   4e-51
UniRef50_Q10XH5 Thiamine-monophosphate kinase n=6 Tax=Cyanobacte...   204   5e-51
UniRef50_UPI00016C3B48 thiamine-monophosphate kinase n=1 Tax=Gem...   203   5e-51
UniRef50_B1CC54 Putative uncharacterized protein n=1 Tax=Anaerof...   203   8e-51
UniRef50_C0GR51 Thiamine-monophosphate kinase n=1 Tax=Desulfonat...   203   1e-50
UniRef50_Q1QUD0 Thiamine-monophosphate kinase n=1 Tax=Chromohalo...   202   1e-50
UniRef50_B3DWZ3 Thiamine monophosphate kinase n=1 Tax=Methylacid...   202   1e-50
UniRef50_B4D453 Thiamine-monophosphate kinase n=1 Tax=Chthonioba...   201   2e-50
UniRef50_Q7NG75 Thiamine-monophosphate kinase n=1 Tax=Gloeobacte...   201   2e-50
UniRef50_D2RH67 Thiamine-monophosphate kinase n=1 Tax=Archaeoglo...   201   3e-50
UniRef50_Q0VMI1 Thiamine-phosphate kinase n=1 Tax=Alcanivorax bo...   201   3e-50
UniRef50_C6A3P3 Hydrogenase expression/formation protein HypE n=...   201   4e-50
UniRef50_A4WH94 AIR synthase related protein domain protein n=5 ...   200   4e-50
UniRef50_A3VRR7 Thiamine-monophosphate kinase n=1 Tax=Parvularcu...   199   8e-50
UniRef50_D1A2J3 AIR synthase related protein n=1 Tax=Thermomonos...   199   1e-49
UniRef50_C6QHP2 Thiamine-monophosphate kinase n=1 Tax=Hyphomicro...   199   1e-49
UniRef50_Q8TVM0 Selenide, water dikinase n=1 Tax=Methanopyrus ka...   199   1e-49
UniRef50_A1K2S2 Thiamine-phosphate kinase n=9 Tax=cellular organ...   199   2e-49
UniRef50_A3DPV0 AIR synthase related protein domain protein n=1 ...   198   2e-49
UniRef50_B2UPF2 Thiamine-monophosphate kinase n=2 Tax=Verrucomic...   198   2e-49
UniRef50_A0B852 Thiamine-monophosphate kinase n=1 Tax=Methanosae...   198   3e-49
UniRef50_Q0APG5 Thiamine-monophosphate kinase n=1 Tax=Maricaulis...   198   3e-49
UniRef50_C7H113 Hydrogenase maturation factor n=1 Tax=Eubacteriu...   198   3e-49
UniRef50_B4UJS8 Thiamine-monophosphate kinase n=7 Tax=Cystobacte...   197   6e-49
UniRef50_B5YKD2 Thiamine-monophosphate kinase n=1 Tax=Thermodesu...   196   7e-49
UniRef50_B6QX74 Thiamine-monophosphate kinase n=1 Tax=Pseudovibr...   196   8e-49
UniRef50_C8S8T5 Thiamine-monophosphate kinase n=1 Tax=Ferroglobu...   196   1e-48
UniRef50_D2RZQ8 AIR synthase related protein domain protein n=1 ...   196   1e-48
UniRef50_Q7UPP0 Thiamine-monophosphate kinase n=1 Tax=Rhodopirel...   195   2e-48
UniRef50_C1F3W9 Thiamine-phosphate kinase n=1 Tax=Acidobacterium...   195   2e-48
UniRef50_C8WEQ3 Thiamine-monophosphate kinase n=5 Tax=Sphingomon...   194   3e-48
UniRef50_C6CVI9 Thiamine-monophosphate kinase n=1 Tax=Paenibacil...   194   3e-48
UniRef50_A6GU77 Thiamine monophosphate kinase n=1 Tax=Limnobacte...   194   3e-48
UniRef50_UPI000038DF5E AIR synthase n=1 Tax=Ferroplasma acidarma...   194   3e-48
UniRef50_A5UMR0 Thiamine monphosphate kinase, ThiL n=3 Tax=Metha...   194   3e-48
UniRef50_C4ZI96 Hydrogenase expression/formation protein n=1 Tax...   194   4e-48
UniRef50_B8D6Q8 AIR synthase related protein domain protein n=1 ...   194   4e-48
UniRef50_B0R9W2 Hydrogenase expression/formation protein n=3 Tax...   194   4e-48
UniRef50_A4A6E1 Thiamine monophosphate kinase n=2 Tax=unclassifi...   194   4e-48
UniRef50_A3UCC4 Thiamine-monophosphate kinase n=1 Tax=Oceanicaul...   194   5e-48
UniRef50_B4WRX3 AIR synthase related protein, C-terminal domain ...   193   9e-48
UniRef50_Q6KZH8 AIR Synthase n=1 Tax=Picrophilus torridus RepID=...   192   1e-47
UniRef50_B1I654 Selenide, water dikinase n=1 Tax=Candidatus Desu...   192   2e-47
UniRef50_Q6AQZ8 Related to hydrogenase expression/formation prot...   192   2e-47
UniRef50_A4BAR6 Thiamine monophosphate kinase n=1 Tax=Reinekea b...   191   2e-47
UniRef50_C6XIX6 Thiamine-monophosphate kinase n=1 Tax=Hirschia b...   191   4e-47
UniRef50_UPI00003C83B8 thiamine monophosphate kinase n=1 Tax=Fer...   191   4e-47
UniRef50_C8W2B7 Selenide, water dikinase n=8 Tax=Bacteria RepID=...   190   7e-47
UniRef50_A8I0K0 Thiamine-monophosphate kinase n=28 Tax=Alphaprot...   190   7e-47
UniRef50_B1H0F2 Thiamine-monophosphate kinase n=1 Tax=uncultured...   189   9e-47
UniRef50_Q73JP8 Selenide, water dikinase n=3 Tax=Bacteria RepID=...   189   1e-46
UniRef50_C7BHY4 Putative uncharacterized protein n=1 Tax=Photorh...   189   1e-46
UniRef50_D2VMQ3 Predicted protein n=1 Tax=Naegleria gruberi RepI...   189   1e-46
UniRef50_C6HZ14 Thiamine-monophosphate kinase n=1 Tax=Leptospiri...   189   2e-46

Sequences not found previously or not previously below threshold:

>UniRef50_A6VPG0 Hydrogenase expression/formation protein HypE n=16
           Tax=Gammaproteobacteria RepID=A6VPG0_ACTSZ
          Length = 337

 Score =  344 bits (883), Expect = 3e-93,   Method: Composition-based stats.
 Identities = 226/335 (67%), Positives = 269/335 (80%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I +AHG+GG AMQ+LI   F EAF NP L + EDQAR+ L +L   G +LAFSTDS+V
Sbjct: 3   DFITMAHGNGGAAMQKLIREYFFEAFNNPILVQGEDQARIPLNELTKCGQKLAFSTDSFV 62

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           IDP+FFPGGNIGKLA+CGTANDVAVSGA+P+YLSCGFILEEGLP+  LK V+ +MAET R
Sbjct: 63  IDPIFFPGGNIGKLAVCGTANDVAVSGAVPKYLSCGFILEEGLPLSELKTVIQAMAETCR 122

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            AGI +VTGDTKVVQ+GAVDK+FINT+G+G IP  + WGA  +  GD ++VSGT+GDHGA
Sbjct: 123 KAGIQVVTGDTKVVQKGAVDKIFINTSGIGVIPDRLDWGAHRIEPGDQIIVSGTIGDHGA 182

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
           TILNLRE LG+  EL SDCAVLTPLI  LR I GVKA+RDATRGGVNAV+HE+  ACG G
Sbjct: 183 TILNLRENLGIQSELQSDCAVLTPLIDLLRPIDGVKAVRDATRGGVNAVLHEYVQACGVG 242

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           + + EAALPV+  VRG+CE+LGL+ALNFANEGKLVI  +     ++L ALHSH LGK+AA
Sbjct: 243 MLIEEAALPVRSEVRGICEILGLEALNFANEGKLVIVAKPEKTAEILTALHSHELGKNAA 302

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG V E K VRLAG++G  R LDLP  EPLPRIC
Sbjct: 303 VIGTVTEDKKVRLAGIFGQTRLLDLPANEPLPRIC 337


>UniRef50_C1F4L5 Hydrogenase expression/formation protein HypE n=5 Tax=Bacteria
           RepID=C1F4L5_ACIC5
          Length = 374

 Score =  338 bits (867), Expect = 2e-91,   Method: Composition-based stats.
 Identities = 157/343 (45%), Positives = 215/343 (62%), Gaps = 14/343 (4%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
           NI + HGSGG+   +LI+ +F++ F NP L   +DQ     A L   G RLAF+TDS+V+
Sbjct: 37  NIVMGHGSGGKLSAELIDKIFVQRFRNPILDRMDDQ-----AVLEIGGMRLAFTTDSFVV 91

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LA+ GT ND+A+ GA P YLS  FILEEGLP + L  VV SM + A A
Sbjct: 92  TPLFFPGGDIGHLAVNGTVNDLAMCGARPLYLSAAFILEEGLPTQDLARVVESMRDAANA 151

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A I +VTGDTKVV RG  DK+FI T G+G +       A     GD +++SG +GDHG T
Sbjct: 152 ANIQLVTGDTKVVNRGKGDKVFITTTGIGIVDRPTEMSADRAQPGDKVILSGFIGDHGIT 211

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLR-------DIPGVKALRDATRGGVNAVVHEFA 235
           IL+ RE L  + +L SDCA L  L++ +        +I G++ +RD TRGGV  V++E A
Sbjct: 212 ILSQREHLEFESDLKSDCAPLHSLVEAMLNEAEANGNIKGIRCMRDPTRGGVATVLNEIA 271

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
                G+ L E+++PV+ +VRG CE+LGLD L  ANEGKL+  V    A+Q++  +  HP
Sbjct: 272 RKSHVGMRLHESSIPVRESVRGACEVLGLDPLYVANEGKLLAVVAPQIADQLIVRMRKHP 331

Query: 296 LGKDAALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           LG ++ +IGE+  +    V +    G  R +D+   E +PRIC
Sbjct: 332 LGTESQIIGEITGQPRDMVLMKTSIGGTRVVDVLFGEQMPRIC 374


>UniRef50_C6PIR8 Hydrogenase expression/formation protein HypE n=3 Tax=Bacteria
           RepID=C6PIR8_9THEO
          Length = 329

 Score =  325 bits (834), Expect = 2e-87,   Method: Composition-based stats.
 Identities = 160/337 (47%), Positives = 220/337 (65%), Gaps = 9/337 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ + L+HG GG  M+ LI  +F +AF N ++   ED A L           + F+TDS+
Sbjct: 1   MDKVLLSHGGGGTMMESLIEEVFSKAFDNEYIKGMEDAALL--------FGNITFTTDSF 52

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IG+LA+CGT ND ++ GA P YL+  FI+EEG PME LK +V SMAETA
Sbjct: 53  TVKPIFFPGGDIGRLAVCGTVNDASMRGAKPLYLTSAFIIEEGYPMEDLKKIVKSMAETA 112

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             AG+ IV GDTKVV++G VD +FINT+G+G +  N+    +    GDV+LVSGT+GDHG
Sbjct: 113 EEAGVKIVAGDTKVVEKGGVDGVFINTSGIGVVYENVDVSIKNAKPGDVVLVSGTIGDHG 172

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACG 239
             I++ RE+L  D  ++SD + L  LI+ L  +   VK LRD TRGGV  V++E +   G
Sbjct: 173 MAIMSAREELQFDPPILSDVSPLNKLIEKLMTLGKAVKVLRDPTRGGVAEVLYEISKMSG 232

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GI++ E  LPVK +V+  CE++G D L+ ANEGKL+  ++R  AE+ L  + S   GKD
Sbjct: 233 VGIKIYEDKLPVKDSVKHACEMMGFDFLHLANEGKLITVIDRKYAEEALEIMKSDKYGKD 292

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGEV + K V +  +YG  R +D P  E LPRIC
Sbjct: 293 AAIIGEVNDSKLVTINTIYGTSRIVDRPIGELLPRIC 329


>UniRef50_C1DUF0 Hydrogenase expression/formation protein HypE n=10 Tax=Bacteria
           RepID=C1DUF0_SULAA
          Length = 332

 Score =  325 bits (833), Expect = 2e-87,   Method: Composition-based stats.
 Identities = 164/339 (48%), Positives = 221/339 (65%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I LAHG GG+  Q+LI  LF + F N  L   ED A L++        ++AF+TDS+
Sbjct: 1   MKQIMLAHGGGGEETQKLIKELFFKYFNNEILLSMEDSAVLNI------NSKVAFTTDSF 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            I P+FF GG+IGKLAI GT ND++V GA P YLSC FI+EEG P E L+ +V SMAE  
Sbjct: 55  TISPIFFSGGDIGKLAIAGTVNDLSVMGAKPLYLSCSFIIEEGFPFEDLEKIVKSMAEEL 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +  G  IVTGDTKVV RG VDK+FINT+G+G +       A  L+ GD ++VSGT+GDHG
Sbjct: 115 KKTGTLIVTGDTKVVPRGFVDKIFINTSGLGKVVYEG-VSAHNLSEGDSIIVSGTVGDHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACG 239
             I+  RE + +  +L+SDC  +  L++ L +    +KA+RD TRGG++AV++E+A +  
Sbjct: 174 VCIMAQREGIDMQTDLISDCDSVWTLVEDLIKGNVKIKAMRDPTRGGLSAVLNEWAESSN 233

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             IE+ E  +PVKP V+G+CELLGL+    ANEG++V+AV +   E+ L  L  +PLGKD
Sbjct: 234 VEIEVLEEKIPVKPQVQGLCELLGLEPYVLANEGRIVVAVSKEDTEKALEILRKNPLGKD 293

Query: 300 AALIGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A LIG+V    +K V L   YG  R ++ P  E LPRIC
Sbjct: 294 AQLIGKVNSKGKKRVILKTSYGSLRIMEPPAGEILPRIC 332


>UniRef50_A4XJQ3 Hydrogenase expression/formation protein HypE n=9 Tax=Clostridia
           RepID=A4XJQ3_CALS8
          Length = 336

 Score =  323 bits (828), Expect = 6e-87,   Method: Composition-based stats.
 Identities = 132/339 (38%), Positives = 190/339 (56%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  IQ  HG+GG+   +LIN LF   F +  L   +D +  DLA           +TDS+
Sbjct: 5   MKFIQKEHGNGGKQTYELINELFKPIFDSEILKRGDDSSIFDLASKKIG-----VTTDSF 59

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FF GG+IGKL++CGT ND+AVSG +P+Y++  FI+EEG P+  L+ +V SM E A
Sbjct: 60  VVKPYFFKGGDIGKLSVCGTVNDLAVSGLVPKYITASFIIEEGFPIVDLQKIVKSMKEYA 119

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN-IHWGAQTLTAGDVLLVSGTLGDH 179
             AG+ IV GDTKVV++G+ D +FINT G G           + +  G V+LVSG +G H
Sbjct: 120 DIAGVEIVAGDTKVVEKGSCDGIFINTTGFGVCEKEEKFPSIEKIKGGQVILVSGDIGRH 179

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
           GA I +   + G + ++ SDCA L  +I  L +   +  ++D TRGG+   ++E A    
Sbjct: 180 GACIYSHNSEFGFEEKIESDCAPLNRVINELLENVEICYMKDLTRGGLATALNEIAQKAN 239

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I + E  +PV   V+ +C++LGLD    A EG+ V  V R   ++ L  L      K+
Sbjct: 240 VAIYVEEDKVPVSNEVKALCDILGLDWYYLACEGRFVAIVNRKNEQRALEILRK--YNKE 297

Query: 300 AALIGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A  IG +   E   V L   +G  R LD+ + + LPRIC
Sbjct: 298 ACEIGWIEDTEENRVYLRTSFGGTRILDMLYYDMLPRIC 336


>UniRef50_Q58089 Putative hydrogenase expression/formation protein MJ0676 n=40
           Tax=cellular organisms RepID=Y676_METJA
          Length = 335

 Score =  319 bits (819), Expect = 7e-86,   Method: Composition-based stats.
 Identities = 122/336 (36%), Positives = 193/336 (57%), Gaps = 4/336 (1%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQED-QARLDLAQLVAEGDRLAFSTDSYV 61
            I   HG+GG+ MQ+LI  + ++      +      ++  D A +      + F+ D + 
Sbjct: 2   KITRMHGAGGKVMQELIKDVILKNLEITSVNGGIGLESLDDSATIPIGDKEIVFTVDGHT 61

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P+FFPGG+IG+LA+ GT ND+AV GA P  LS   I+ EG  +E L+ +V S+ ET++
Sbjct: 62  VKPIFFPGGDIGRLAVSGTVNDLAVMGAKPLALSLSLIIPEGFNLEDLEKIVKSINETSK 121

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            A +AI+TGDTKV     VD + I+TAG+G +          +  GD ++VSG +G+HG 
Sbjct: 122 EAEVAIITGDTKVSD--GVDDIIISTAGIGIVDRGKAIRDCNVQEGDAIIVSGNIGEHGL 179

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGC 240
            IL  RE    +  + SD A +  LI+ + +    + A++D TRGG+   ++E A     
Sbjct: 180 AILLSREGFDFETNIKSDVAPINKLIERVLEEGIQINAMKDPTRGGLADALNEMAEKSNI 239

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           GI + E  +P+   V+ +C++LGLD L  ANEGK+V+AV++  AE+ L  L  HPLGK+A
Sbjct: 240 GITIFEDKIPISDEVQSICDILGLDPLTIANEGKVVMAVKKEDAERCLEILREHPLGKNA 299

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            +IG   +     +      +R +D+P  +P+PR+C
Sbjct: 300 EIIGYATKEHKGVIIETIVGRRIVDMPIGDPIPRVC 335


>UniRef50_P40599 Hydrogenase expression/formation protein hypE n=110 Tax=Bacteria
           RepID=HYPE_RHILV
          Length = 350

 Score =  312 bits (801), Expect = 9e-84,   Method: Composition-based stats.
 Identities = 156/338 (46%), Positives = 211/338 (62%), Gaps = 9/338 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            I L+HG+GG+AM QLI  +F +AF N WL    DQ+          G R+  +TD YV+
Sbjct: 18  RIDLSHGAGGRAMGQLIEGIFHKAFDNDWLRAGNDQS-----AFSVPGGRMVMTTDGYVV 72

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGGNIG LA+ GT ND+A++GA+P YLS  FI+EEG P+  L+ +  SM   +R 
Sbjct: 73  SPLFFPGGNIGTLAVHGTINDIAMAGAVPLYLSASFIIEEGFPLVDLERIADSMGAASRE 132

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ I+TGDTKVV+RG  D +FI+TAG+G  P  +   +     GD +++SG++GDHG  
Sbjct: 133 AGVPIITGDTKVVERGKADGVFISTAGIGMAPDGLDLRSDAARPGDAVIISGSIGDHGVA 192

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVK--ALRDATRGGVNAVVHEFAAACGC 240
           +++ RE L  D ++VSD A L  L+  +    G     +RD TRGG+ A ++E A+    
Sbjct: 193 VMSKRENLEFDTDIVSDSAALHGLVADMVAAGGAHIRLMRDPTRGGIAATLNEIASQSRV 252

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G  + E A+P+KP V   CE LGLD LN ANEGKLV  V    A+ VLAA+H+HPLG +A
Sbjct: 253 GFRIDEEAIPMKPEVAAACEFLGLDPLNVANEGKLVAVVAPEGADAVLAAIHAHPLGAEA 312

Query: 301 ALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           ALIG VV      V++   +G  R +D    E LPRIC
Sbjct: 313 ALIGHVVADDNYFVQMVTSFGGGRIVDWLSGEQLPRIC 350


>UniRef50_B8D1S4 Hydrogenase expression/formation protein HypE n=3 Tax=Bacteria
           RepID=B8D1S4_HALOH
          Length = 334

 Score =  312 bits (799), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 143/339 (42%), Positives = 218/339 (64%), Gaps = 8/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           MN I LAHG+GG+ M+ LI++LF++   N  + +++D +      +         STD++
Sbjct: 1   MNTISLAHGNGGKMMEDLIDNLFLKYLNNDIINKKDDAS-----PVPEIKGVPVISTDTF 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+DP+FFPGGNIGKL+ICGT ND+AV+GAIP YL+ GFILEEGLP++ L+ ++ SMAE +
Sbjct: 56  VVDPIFFPGGNIGKLSICGTVNDLAVTGAIPLYLTVGFILEEGLPIKHLEKIIISMAEVS 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           R A + IV GDTKVV+RG  DK+FINT G+G I   +    + +  GD ++++G++ +HG
Sbjct: 116 REANVKIVAGDTKVVERGKGDKIFINTTGVGMIGDKLKLSDENIKLGDKVIINGSIAEHG 175

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
             IL  R Q+     + SDC  L+ LI   L +  G+K +RD TRGG+  V++E A    
Sbjct: 176 LAILMERNQMDFSTSIKSDCCTLSDLIVTLLSETNGIKFMRDPTRGGMATVLNEIATRYN 235

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GIE+ E  +P+   ++ +C++LGLD L  ANEGK++I  +R  +E+++  +  HP G++
Sbjct: 236 VGIEIEEEKVPLGDEIKSLCKILGLDPLYLANEGKVLIIADREKSEKIVDIMRRHPYGRN 295

Query: 300 AALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           +++IG +V+     V L    G KR +     + LPRIC
Sbjct: 296 SSIIGTIVDNNDQQVYLKTRIGGKRIITKLMHDMLPRIC 334


>UniRef50_Q0HUQ3 Hydrogenase expression/formation protein HypE n=38 Tax=Bacteria
           RepID=Q0HUQ3_SHESR
          Length = 339

 Score =  308 bits (790), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 155/336 (46%), Positives = 209/336 (62%), Gaps = 10/336 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           IQL+HG GG+ M +LI  LF   F NP L  +ED A+L+L          AF+TDS+ + 
Sbjct: 11  IQLSHGGGGKEMNKLIRELFFAEFDNPILRSEEDAAKLELQ------GATAFTTDSFTVS 64

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFF GG+IGKLAI GT ND+A+ GA P+YLSC  I+EEG  +  L  +V SMA+  + +
Sbjct: 65  PLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSLNQLTTIVRSMAKELKQS 124

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           G  IV GDTKVV +G  D LFINT+G+G I       A  +  GD ++VS  +G HGA I
Sbjct: 125 GARIVCGDTKVVPKGCADGLFINTSGVGRILRPN-ISAANVAPGDAIIVSRDVGCHGAAI 183

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGI 242
           L  RE L L+  L SDCA L P+++ L      + A+RDATRGG++AV++E+AAA   GI
Sbjct: 184 LMAREGLTLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAAAANVGI 243

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            ++EA++PV   V+G+CEL G +A++ ANEG  ++AV  + A   L  +      + AA+
Sbjct: 244 TVNEASIPVCDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGHCEQAAI 303

Query: 303 IGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           IG V +     V L   +  KR LDLP  E LPRIC
Sbjct: 304 IGTVSDELPGKVILRTPWNTKRYLDLPQGELLPRIC 339


>UniRef50_A8ZNR3 Hydrogenase expression/formation protein HypE n=17 Tax=Bacteria
           RepID=A8ZNR3_ACAM1
          Length = 362

 Score =  308 bits (790), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 147/352 (41%), Positives = 198/352 (56%), Gaps = 24/352 (6%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG GG+ M QLI  +F   F +      ED+   D A L     RLA +TDSYV+
Sbjct: 17  QVLLAHGGGGKLMHQLIEQMFGRLFQS------EDRHHHDAAVLGVPPGRLALTTDSYVV 70

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LA+ GT ND+A++GA P YLS  FILEEGL M TL  VV SM + A  
Sbjct: 71  HPLFFPGGDIGSLAVYGTVNDLAMAGARPLYLSTSFILEEGLSMTTLWQVVQSMQQAAHQ 130

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A + IVTGDTKVV+RG  D +FINTAG+G I  +     Q++  GD+++++G LG HG  
Sbjct: 131 ADVQIVTGDTKVVERGKGDGVFINTAGVGIIEHHQTIHPQSIQPGDLVILNGDLGRHGMA 190

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCG 241
           +L  RE L  + E+ SD A L  ++  L      +  +RD TRGG+ + ++E A A G  
Sbjct: 191 VLAEREGLEFESEIKSDSAPLNHVVLDLFAHGVELHCMRDLTRGGLASALNEIALATGVA 250

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS-------- 293
           I L E  +P++  V+G CE+LG D L  ANEG+ +  V   + +  LA L++        
Sbjct: 251 ISLDETCIPIREDVQGACEILGFDPLYVANEGRFIAFVPPQSVDLALARLNAPLSFPLSG 310

Query: 294 -------HPLGKDAALIGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
                        A +IG+V       V L    GV+R +D    E LPRIC
Sbjct: 311 QSDTHPQMRHQHPAQVIGQVTTTTSPRVTLTNRLGVERIVDFLSGEQLPRIC 362


>UniRef50_C6PPZ0 Hydrogenase expression/formation protein HypE n=6 Tax=Clostridiales
           RepID=C6PPZ0_9CLOT
          Length = 334

 Score =  307 bits (787), Expect = 4e-82,   Method: Composition-based stats.
 Identities = 144/340 (42%), Positives = 204/340 (60%), Gaps = 10/340 (2%)

Query: 1   MNNI-QLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDS 59
           M+ I  LAHG+GG+   +LI+ +F   F+NP      D    D A L  +G +LAF+TD 
Sbjct: 1   MDKIVTLAHGAGGRQTSELIDQVFKAHFSNP------DLTADDAAVLNVKGGKLAFTTDG 54

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           +++ P  FPGGNIGKL+ICGT ND++  GA P YLSC F++EEG PME L+ +  +M +T
Sbjct: 55  FIVSPSEFPGGNIGKLSICGTVNDLSCMGAKPLYLSCAFVIEEGFPMEKLEKIAAAMEKT 114

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
           A  AG+ IV GDTKV  +G VD +FI T G+G I   ++        GD ++V+G +G H
Sbjct: 115 ADEAGVKIVAGDTKVAGKGQVDGVFITTTGIGQIIDGVNTSGFNAKPGDAIIVTGDIGRH 174

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLR-DIPGVKALRDATRGGVNAVVHEFAAAC 238
           G T+L  R + G++ ++VSDCA L   ++ +  +   +  +RDATRGGV  V++E A   
Sbjct: 175 GCTVLLARNEFGIEADVVSDCAPLWGTVKAMLDESKDIHVIRDATRGGVGTVLYEIAEQS 234

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI L   ++PV   V+GVC +LGL+ L  A EG+LVI   +  A +++  LH     K
Sbjct: 235 KVGIRLDSKSIPVADGVKGVCGMLGLEPLYLACEGRLVIFAPKEVAPKLVDTLHEGKYSK 294

Query: 299 DAALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           DAA+IGEV +     V +    G +  L  P  E LPRIC
Sbjct: 295 DAAIIGEVTQDMAGRVIVKTEIGAETLLPPPGGELLPRIC 334


>UniRef50_P31906 Hydrogenase expression/formation protein hypE n=170 Tax=Bacteria
           RepID=HYPE_BRAJA
          Length = 346

 Score =  303 bits (777), Expect = 5e-81,   Method: Composition-based stats.
 Identities = 167/337 (49%), Positives = 214/337 (63%), Gaps = 9/337 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           + L+HGSGG+AM QLI+ LF EAF N WLA   DQ+  D+        R+  +TD YV+ 
Sbjct: 15  VDLSHGSGGRAMAQLISGLFHEAFGNEWLARGNDQSAFDVRA-----GRMVMTTDGYVVS 69

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGGNIG LA+ GT ND+A++GA P YLS  FI+EEG     LK +  SM   AR A
Sbjct: 70  PLFFPGGNIGSLAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFADLKLIAESMGAAAREA 129

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            + I+TGDTKVV+RG  D LFI+TAG+G +P  +   A+    GD +L+SGTLGDHG  I
Sbjct: 130 DVHIITGDTKVVERGKADGLFISTAGVGVVPDGLDLSAEKARVGDRVLISGTLGDHGVAI 189

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIP--GVKALRDATRGGVNAVVHEFAAACGCG 241
           ++ R+ L  + E+VSD A L  L+  +      G++ +RD TRGG+ A ++E A     G
Sbjct: 190 MSKRQNLAFETEIVSDSASLHDLVARMVQAGGRGIRLMRDPTRGGLAATLNEIAQQSNLG 249

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             L E A+PVKP V   CELLGLD L+ ANEGKLV  V   AA  VLAA+ +HPLG+DAA
Sbjct: 250 FHLLEEAIPVKPGVAAACELLGLDPLHVANEGKLVAIVAPEAAGAVLAAMRAHPLGRDAA 309

Query: 302 LIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            IGE V      V++A  +G  R +D    E LPRIC
Sbjct: 310 DIGEAVADDHHFVQMATSFGGGRIVDWLSGEQLPRIC 346


>UniRef50_B7JZ80 Hydrogenase expression/formation protein HypE n=17 Tax=Bacteria
           RepID=B7JZ80_CYAP8
          Length = 348

 Score =  303 bits (776), Expect = 6e-81,   Method: Composition-based stats.
 Identities = 155/339 (45%), Positives = 205/339 (60%), Gaps = 12/339 (3%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG GG+ MQQL+  +F  AF         D      A L    +++AF+TDSYVI
Sbjct: 17  QVLLAHGGGGKLMQQLLEKMFFPAFKTTHNIPPHDS-----AVLSLNTNKIAFTTDSYVI 71

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            PLFFPGG+IG LAI GT ND+A+SGA P YLS GFILEEGLPMETL  VV S+ + A+ 
Sbjct: 72  HPLFFPGGDIGSLAINGTVNDLAMSGARPLYLSVGFILEEGLPMETLWRVVQSLQKAAQI 131

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           A + I+TGDTKVV  G  D +FINTAG+G +  N     Q++  GD +L+SG LG HG  
Sbjct: 132 AEVQIITGDTKVVDHGKGDGIFINTAGVGIVEHNQVIAPQSVQPGDAILISGDLGRHGIA 191

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCG 241
           I+ +RE L  +  + SDCA L+ L+  + D    +  LRD TRGG+ + ++E A   G  
Sbjct: 192 IMAVREGLEFETAIESDCAPLSTLVLEMLDAGVEIHCLRDLTRGGLASALNEIATGAGVT 251

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           +++ E A+PV   V+G CE+LG D L  ANEG+LV  + +N+  + L  L SH     A+
Sbjct: 252 LKVQETAIPVAEDVQGACEILGFDPLYVANEGRLVAFIPQNSVSRALEILRSHHQ--QAS 309

Query: 302 LIGEVV-ERKG---VRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG+V     G   V L    G  R LD+   E LPRIC
Sbjct: 310 IIGQVTGTGTGMGLVTLESRIGASRILDMLSGEQLPRIC 348


>UniRef50_B2TM78 Hydrogenase expression/formation protein HypE n=4 Tax=Clostridium
           RepID=B2TM78_CLOBB
          Length = 337

 Score =  301 bits (772), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 142/339 (41%), Positives = 210/339 (61%), Gaps = 9/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
             I L+HGSGG    +LI+ +F   F N  L +Q D   L+         ++A + D +V
Sbjct: 4   KIITLSHGSGGIETYKLIDEMFYRNFNNDELLQQGDSTVLN-----EIKGKIATTIDGFV 58

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           +DP+FF GG+IGKL++CGT ND+AVSGA P Y++C FI+EEG   ++L+ +V SMA+TA+
Sbjct: 59  VDPIFFKGGDIGKLSLCGTINDLAVSGACPLYITCSFIIEEGFEFKSLEKIVQSMAKTAK 118

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI-HWGAQTLTAGDVLLVSGTLGDHG 180
            + + IV GDTKVV++G   K++I+T G+G             + +GD +++SGT+G+HG
Sbjct: 119 ESNVKIVAGDTKVVEKGKGHKVYISTCGIGYFKEQKNILNVNNIKSGDKIILSGTIGEHG 178

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACG 239
             I+N RE L +D E+ SDCA L  L + + +    V+ +RD TRGG+   ++E + +  
Sbjct: 179 MCIVNKRENLNIDSEIKSDCAPLNSLCEIILNTSNNVRIMRDPTRGGIANTLNELSRSSL 238

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             + + E  +P+   VR   ELLG+  L  ANEGKL+  V+   AE VL+A+ +HPLGKD
Sbjct: 239 KSMMIYEEFIPINNDVRSFFELLGMSPLYIANEGKLLCIVDEVDAENVLSAMKNHPLGKD 298

Query: 300 AALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGEV+E     V + GL G  + L +   E LPRIC
Sbjct: 299 AAIIGEVIEENKGAVYIKGLLGSTKVLQMSQGELLPRIC 337


>UniRef50_C5ZXL6 Hydrogenase expression/formation protein HypE n=4 Tax=Helicobacter
           RepID=C5ZXL6_9HELI
          Length = 340

 Score =  301 bits (772), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 145/337 (43%), Positives = 207/337 (61%), Gaps = 6/337 (1%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I L+HGSGG   Q+LI+ LF        +   ED    +L  +     + A STD Y I 
Sbjct: 6   ITLSHGSGGVESQKLISELFYPFLEGCVIGNGEDAGIGELDSISQG--KFAISTDGYTIS 63

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           PLFFPGG+IGKL+ICG+ NDVA+ GA P+YLS  F++EEG  ++ LK ++ S  +T +A+
Sbjct: 64  PLFFPGGDIGKLSICGSCNDVAMMGAKPKYLSASFMIEEGFLIDDLKKILDSFGKTLKAS 123

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGA-IPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           G  +++GDTKV+ +G +DK+FI T   G  +  ++   A  +     +LVSG +G+HGA 
Sbjct: 124 GAKLLSGDTKVLPKGTLDKIFITTTAFGEFLYPHLQISAFNIPQDCCILVSGEIGNHGAV 183

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
           + + RE++ L   L SDC +L P ++ L ++   + ALRDATRGG+ +V++E+A A   G
Sbjct: 184 VYSKREEISLQSNLESDCQLLYPSLEELFKNNLSIYALRDATRGGIASVLNEWANASHIG 243

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IE+ E  LP+K  VRG+CELLG +A N ANEG  V+A+ +  +++ L  L   P GK+A 
Sbjct: 244 IEIEEETLPIKDEVRGICELLGFEAWNLANEGMCVLAIAKEDSKKALEILKRTPAGKNAT 303

Query: 302 LIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +IG         V L   YG KR LD P  E LPRIC
Sbjct: 304 IIGYTTSTNLNKVVLKTAYGAKRFLDYPSGELLPRIC 340


>UniRef50_B9KGD0 Hydrogenase expression/formation protein HypE n=1 Tax=Campylobacter
           lari RM2100 RepID=B9KGD0_CAMLR
          Length = 336

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 138/339 (40%), Positives = 190/339 (56%), Gaps = 19/339 (5%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I LAHG GG+ M  LIN +F   F N  L E  D A LD          LAFSTDS+
Sbjct: 14  MKQITLAHGGGGEEMNALINEIF-SIFENDVLKEANDAAILDD---------LAFSTDSF 63

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V++P+F    NIGKLA+CG+ NDV + GA P YLS   ILEEG  +E LK ++ S+ E  
Sbjct: 64  VLNPIFLKDINIGKLAVCGSVNDVLMVGAKPLYLSLALILEEGFEIEKLKIILNSIKEEC 123

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             AG+ +V GDTKVV +   D+++INT+ +G          + L +G  +LVS  +G HG
Sbjct: 124 DKAGVKLVCGDTKVVPKNKGDEIYINTSCIG--KNIQKINTKNLKSGCSILVSRDIGAHG 181

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACG 239
             +L  R  L  +  + SDC  L   +  L +    +KA+RDATRGG++AV++E++    
Sbjct: 182 CAVLVERNNL--EANIQSDCKSLKNEVLALLNAGISIKAMRDATRGGLSAVLNEWSKLSN 239

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             + + E  +PV   V GVCEL G +    ANEG  +I V++   ++ L  L       +
Sbjct: 240 LELLIYEEKIPVCDEVLGVCELFGYEPYELANEGTFIICVDKKDEQKALKILK--QFNAN 297

Query: 300 AALIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGE+   E+  V L   YG KR L+ P  E LPRIC
Sbjct: 298 AAIIGEITPNEKARVVLENAYGAKRILETPKGELLPRIC 336


>UniRef50_B0TWC9 Hydrogenase expression/formation protein HypE n=3 Tax=Francisella
           philomiragia RepID=B0TWC9_FRAP2
          Length = 341

 Score =  300 bits (768), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 154/336 (45%), Positives = 211/336 (62%), Gaps = 9/336 (2%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           + LA G+GG+AM  LI  +  ++F + +LA+ EDQA L          ++A +TDSYVI 
Sbjct: 12  VDLAMGAGGKAMHHLIEQMIKKSFDSQYLAQAEDQAIL-----PQINGKIAMTTDSYVIT 66

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P FF GGNIG LAI GT ND+ V GA P Y+S G ILEEGLP+  LK ++ SMAETA+ A
Sbjct: 67  PYFFRGGNIGSLAIHGTVNDLVVGGAKPLYISVGLILEEGLPLRDLKVILDSMAETAKKA 126

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
            + IVTGDTKVV++G  D +FINT G+G I  +      TL  GD ++++GTLGDHG  +
Sbjct: 127 NVQIVTGDTKVVEKGKGDGIFINTTGVGVI-RDDFVTRDTLEDGDEIIINGTLGDHGVAV 185

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGI 242
           ++ R  L  + ++VSD   L  L+  + D    +K +RD TRGGV A ++E+A      I
Sbjct: 186 MSQRAGLDFECQIVSDATSLDSLVDAIYDNKCQIKTMRDPTRGGVGATLNEWANQYNVAI 245

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+ EA LP+   V+  CELLGLD L  ANEGK++IA + +  ++VL  L  HPLG++A +
Sbjct: 246 EIDEANLPISTEVQSACELLGLDPLYIANEGKVLIACKPSQTQKVLDCLRGHPLGENAQV 305

Query: 303 IGEVV--ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           I  V   E+  V +   +G KR +D    E LPRIC
Sbjct: 306 IATVRKSEQSQVFMKTTFGGKRRVDWLSGEQLPRIC 341


>UniRef50_Q39ZF9 Hydrogenase expression/formation protein HypE n=3
           Tax=Deltaproteobacteria RepID=Q39ZF9_GEOMG
          Length = 349

 Score =  300 bits (768), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 154/338 (45%), Positives = 204/338 (60%), Gaps = 8/338 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I L HGSGG+   QL++ L +   +   L       + D A +   G RLAF+TDSYV
Sbjct: 17  DLILLGHGSGGKLSHQLLDDLIIPTLSGIPL-----AGQNDAAVVEHGGQRLAFTTDSYV 71

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           +DP+FFPGGNIG LA+ GT ND+A+ GA P ++S G I+EEG     L  ++ SM   A 
Sbjct: 72  VDPIFFPGGNIGSLAVNGTVNDLAMMGARPLFISAGLIVEEGFSRTELAGILASMRGAAD 131

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           AAG+ IVTGDTKVV RG  D++FINT+G+GA+  +         AGDV++++GT+GDHG 
Sbjct: 132 AAGVRIVTGDTKVVPRGKADRIFINTSGIGAVEHDFAINGANARAGDVVIINGTIGDHGI 191

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACG 239
            ++  RE L L   + SDCA L  L+  +    G  V  LRD TRGGV   + E A    
Sbjct: 192 AVMAEREGLDLRTAIRSDCAALNDLVAEIIAAGGDAVHVLRDPTRGGVATTLKEIALQSD 251

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I L E  LP+  AV+GVC +LGLD L  ANEGKL+  V   AAE+VL  +  H LG+D
Sbjct: 252 KTITLREETLPLNGAVKGVCSILGLDPLYVANEGKLLAVVAPEAAERVLTRIKGHRLGRD 311

Query: 300 AALIGEVVERKG-VRLAGLYGVKRTLDLPHAEPLPRIC 336
           AA+IG V E  G V++    G  R +++   E LPRIC
Sbjct: 312 AAIIGHVAEGGGRVQMETAVGGMRAVEMLAGEQLPRIC 349


>UniRef50_B0TCN4 Hydrogenase expression/formation protein hype n=6 Tax=Firmicutes
           RepID=B0TCN4_HELMI
          Length = 360

 Score =  299 bits (766), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 158/362 (43%), Positives = 206/362 (56%), Gaps = 32/362 (8%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
             I LAHG GG    +L+  +F+  F +P L +  D      A L     RLA +TD++V
Sbjct: 4   ECILLAHGDGGALTHRLVQEIFLRHFDHPALRDLTDA-----ALLHLPEGRLAMTTDTFV 58

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG+IGKLA+ GT ND+AVSGA P YL+  FILEEG P+  L+ VV S+A TAR
Sbjct: 59  VKPLFFPGGDIGKLAVAGTVNDLAVSGARPLYLTAAFILEEGFPLADLEQVVASLARTAR 118

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            AG+A+V GDTKVV+RG  D ++INT G G +PA    G   +  GD ++V+GT+GDHG 
Sbjct: 119 EAGVAVVAGDTKVVERGCGDGVYINTTGAGVVPAGRDLGYHRIMPGDAVIVNGTIGDHGL 178

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRD--IPGVKALRDATRGGVNAVVHEFAAACG 239
            IL+ R  +  D  + SDCA +  L   L +     V+ +RD TRGGV   ++E A + G
Sbjct: 179 AILSKRAGIEFDTPVESDCAPMNGLTDMLLERFAEAVRFMRDPTRGGVATTLNEVAQSTG 238

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I L E ALPV+  V+G  ELLGLD L  ANEGK++I     A E++L  L  HPLG +
Sbjct: 239 LNIILEEQALPVREEVQGAAELLGLDPLYLANEGKVLIVAAPEAVEEILTTLRRHPLGLN 298

Query: 300 AALIGEVVERKG-------------------------VRLAGLYGVKRTLDLPHAEPLPR 334
           AA IG V    G                         V L    G  R +D+   +PLPR
Sbjct: 299 AAAIGRVEAGTGVGRGPGQGAGQRTGQGSGQGAGRGRVFLRTPLGGHRIVDMLAGDPLPR 358

Query: 335 IC 336
           IC
Sbjct: 359 IC 360


>UniRef50_B4U670 Hydrogenase expression/formation protein HypE n=2 Tax=Bacteria
           RepID=B4U670_HYDS0
          Length = 328

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 124/336 (36%), Positives = 203/336 (60%), Gaps = 13/336 (3%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           ++L+HG G +  ++LI  +F++   N  L+ ++       A ++    +LA STDS+ ++
Sbjct: 3   VKLSHGGGAKETRELIEKIFLKHLKNDLLSNED-------ATILHLDGKLAISTDSFTVN 55

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P+FF GG+IGKL++ G  ND++V GA P Y+S GFI+EEGL  E L+ +V S+ E A+  
Sbjct: 56  PIFFKGGDIGKLSVAGVVNDLSVMGAKPLYMSMGFIIEEGLAFEELERIVISIKEEAQKT 115

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI 183
           GI ++T DTKVV +G  DK++IN  G+G +       A  L  GD ++VSG +G+HGA I
Sbjct: 116 GIKLITADTKVVPKGLCDKIYINATGIGKLIKEG-ISASNLQEGDAIVVSGPIGNHGAVI 174

Query: 184 LNLREQLGLDGELVSDCAVLTPLIQ-TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           +  R    +D  + SDCA L   I+  L++   + A+RD TRGG+ + ++E + +    I
Sbjct: 175 MAHRNGFDID--INSDCASLWEAIEPLLKENIEIHAMRDLTRGGLASALNELSQSSKVEI 232

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            + E  +P++ +V+G CE+LG++  + A EG  V+++ +   ++ L  L S  L + A +
Sbjct: 233 LIKEEDIPIEDSVKGFCEILGIEPFSLACEGTFVMSIPKKDVQKALDILKSQKLTQKAKV 292

Query: 303 IGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           IGE++++   G  +  LYG  R L+    E LPRIC
Sbjct: 293 IGEIIKKGKQGAYIQTLYGSVRYLEEAPGELLPRIC 328


>UniRef50_D2ATM4 Hydrogenase maturation factor-like protein n=35 Tax=Bacteria
           RepID=D2ATM4_STRRD
          Length = 446

 Score =  296 bits (759), Expect = 6e-79,   Method: Composition-based stats.
 Identities = 168/340 (49%), Positives = 216/340 (63%), Gaps = 14/340 (4%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I LAHG+GG+A   LI ++F+EAF NP L   ED A +D          LAF+TDSYV
Sbjct: 116 DRITLAHGAGGKATHTLIEAVFLEAFRNPLLEPLEDGAVVD---------GLAFTTDSYV 166

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG+IG LA+ GT ND+A+ GA PRYLS  FI+EEG P+  L+ +  SMA  AR
Sbjct: 167 VTPLFFPGGDIGDLAVNGTVNDLAMCGARPRYLSAAFIVEEGFPVADLRRITASMAAAAR 226

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           AA + IVTGDTKVV+ G  D  +I T+G+G +   I   A     GDV++VSG +G+HG 
Sbjct: 227 AADVWIVTGDTKVVENGKADGCYITTSGVGTVERPIRLSAAAARPGDVVIVSGPIGEHGV 286

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VKALRDATRGGVNAVVHEFAAAC 238
           T++  R +L +  +L SD A L  L   L D  G   V+ LRDATRGGV  VV+E A A 
Sbjct: 287 TVMLARGELDIQADLTSDTAPLNTLTGRLLDACGDGQVRCLRDATRGGVATVVNEIAVAS 346

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
              + L E A+PV PAVRG CELLG+D L  A EG++V  V + +AE  LAAL SHPLG 
Sbjct: 347 KVAVVLEEDAIPVCPAVRGACELLGIDPLYVACEGRMVAVVAQRSAEAALAALRSHPLGS 406

Query: 299 DAALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           +AA+IG + +     V L   +G  R +DL   +PLPRIC
Sbjct: 407 EAAVIGRIGDDPPGLVLLKTSFGGTRIVDLLVGDPLPRIC 446


>UniRef50_B2UW48 Hydrogenase expression/formation protein n=12 Tax=Helicobacter
           RepID=B2UW48_HELPS
          Length = 332

 Score =  295 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 137/339 (40%), Positives = 202/339 (59%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+++ LA G+GG+    LI  +FM     P+L E       D  +  A G+    STDS+
Sbjct: 1   MDSVTLACGNGGKETNALIERVFM-----PYLKEFIVAFDEDAPKFKASGEYCV-STDSF 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           VI PL F GG+IGKL +CG+ANDV+V G  P YL+ GFILEEGL +  LK ++ S+ +  
Sbjct: 55  VITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKEL 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
             A + +++ DTKVV +G+VDKLFINT  +G            L  G  +++S T+ +HG
Sbjct: 115 LKANLKLLSLDTKVVPKGSVDKLFINTTCIGKTIKPGISSRY-LKQGQAIIISDTIANHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACG 239
           A++  +R ++ L   L SDC +L PL++ L      + ALRDATRGG+ +V++E+A +  
Sbjct: 174 ASLFAMRHEIKLKTNLESDCQLLYPLLKPLFLSDLKIHALRDATRGGLASVLNEWANSSK 233

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             I + E  +P+K   +G+CE+LGL+    ANEG  V+A+ +  A + L  L S+   K+
Sbjct: 234 VKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLAINQKDAPKALEILKSNEKAKN 293

Query: 300 AALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A +IGEV E     V L   +G +R L++P  E LPRIC
Sbjct: 294 ACVIGEVFENPYPSVVLKNAWGFERILEMPEGELLPRIC 332


>UniRef50_A4CGN3 Hydrogenase expression/formation protein HypE n=2
           Tax=Flavobacteriaceae RepID=A4CGN3_9FLAO
          Length = 339

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 143/339 (42%), Positives = 199/339 (58%), Gaps = 10/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + I L HGSGG    +L++S     F N  L ++ D A L          + AF+TDS+V
Sbjct: 7   DIITLGHGSGGLLTNKLLDSGVFHLFDNEHLQQRHDGAML------TLEGKTAFTTDSFV 60

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           I P+FFP  NIG+LA+ GT ND+A+ GAIP+YLS  FILEEGL M     ++ S+   A 
Sbjct: 61  ISPIFFPDSNIGELAVNGTVNDLAMCGAIPQYLSLSFILEEGLKMTEFWEILVSIKSAAE 120

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            A I IVTGDTKVV+RG  DK+FINT G+G + A        +  GD ++VS ++  HG 
Sbjct: 121 QANIQIVTGDTKVVERGKGDKIFINTTGIGQLHAKADIAPSNVQPGDKIIVSDSIATHGV 180

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGV--KALRDATRGGVNAVVHEFAAACG 239
            I+++RE L  + EL SD   L+ ++  L D  GV    L+D TRGGV  V++E A    
Sbjct: 181 AIMSVREGLEFESELKSDTRGLSHMVSELLDTFGVDIHLLKDPTRGGVATVLNEIARDRN 240

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GIE+ +  LP++  V  +CE+LGLD L  ANEG  +  V+   +E+V+  L S   G +
Sbjct: 241 LGIEILQKDLPLQNEVSALCEILGLDPLYVANEGIFIAVVKDAISEKVVEKLQSMEYGAN 300

Query: 300 AALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A++IG+V E   K V L    G +R +++   E LPRIC
Sbjct: 301 ASIIGDVTENHPKQVVLKSAIGGRRIVNMLAGEQLPRIC 339


>UniRef50_B7JF80 Hydrogenase expression/formation protein HypE n=32 Tax=Bacteria
           RepID=B7JF80_BACC0
          Length = 342

 Score =  292 bits (749), Expect = 9e-78,   Method: Composition-based stats.
 Identities = 134/341 (39%), Positives = 208/341 (60%), Gaps = 10/341 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           + NI L HG+GG   Q LI+S+         L + ED A L+         RLA +TDS+
Sbjct: 7   LENIILDHGTGGLLSQDLISSIITAKLEGVHLGKMEDSAILE-----VSSRRLAMTTDSF 61

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           VIDP+FF  GNIGK+A+CGT ND+AVSGA P YLS   +LEEG P++ L+ ++ S+ ETA
Sbjct: 62  VIDPIFFGEGNIGKVAVCGTVNDLAVSGAKPLYLSLALVLEEGFPIKDLEEILDSIRETA 121

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI-HWGAQTLTAGDVLLVSGTLGDH 179
           + AG+ IV GDTKVV++G VDK+FINT G+G    ++  +   ++  GD ++++G LG+H
Sbjct: 122 KEAGVYIVAGDTKVVKKGEVDKIFINTTGIGVFEGDVSPFSVNSIQEGDDIIITGQLGNH 181

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAA 237
              IL++RE LG +  + SDCA L  +I  L++  G  +  +RD TRGG+  V++E +  
Sbjct: 182 SIHILSIREGLGFEQRINSDCAPLNHMITELKNHFGDSIHCMRDITRGGLGTVLNEVSET 241

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
              GI++ E  +P+        ++LG++ +  ANEG + + V    +E+V+  L +   G
Sbjct: 242 INTGIKIQEKDIPMLAETIMAADMLGVNPMYLANEGNVCMFVSPEVSEEVVRVLKNTKYG 301

Query: 298 KDAALIGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           K+AA+IG+V   + + V +    G  + ++L +   LPR+C
Sbjct: 302 KEAAVIGKVTQTKERQVLMEAKSGELKLIELLYGAELPRLC 342


>UniRef50_A6LXR5 Hydrogenase expression/formation protein HypE n=3 Tax=Clostridium
           RepID=A6LXR5_CLOB8
          Length = 333

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 148/340 (43%), Positives = 211/340 (62%), Gaps = 11/340 (3%)

Query: 1   MNN-IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDS 59
           MN  I+L HG GG+  + LI  LF + F N  L +++D      A   A   ++AF+TDS
Sbjct: 1   MNKMIKLIHGDGGKHTKILIEQLFYKYFNNNILLQEQDS-----ATFTAVQGKMAFTTDS 55

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           +V+ PLFF GGNIGKLA+CGT ND+AVSGA P YLS  FI+EEG  M++L+ +V SM +T
Sbjct: 56  FVVKPLFFSGGNIGKLAVCGTINDLAVSGAKPFYLSSSFIIEEGFSMQSLEEIVKSMGQT 115

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
               G  IVTGDTKVV++G+VD +FINT+G+G I          +  GD ++V+G +G+H
Sbjct: 116 CLECGAKIVTGDTKVVEKGSVDGIFINTSGIGYIINGYEVKP--IEEGDKIIVTGEIGEH 173

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAAC 238
           G TI   R  L + G+  SDCA L   I+ L++  P +K +RD TRGG++ V+HEF++ C
Sbjct: 174 GTTIAVERYNLKVKGDYKSDCAPLFHFIEELKEQFPSIKIMRDPTRGGLSTVLHEFSSLC 233

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI L E  +P+  +V+ +  LLGLD L  A EG++V+ V+   A++VL  + S   GK
Sbjct: 234 KLGIHLIEKEIPISESVKAINNLLGLDPLYMACEGRMVLVVKETEAKKVLDIIRSIDQGK 293

Query: 299 DAALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
            A +IGE ++     + +   +G KR +       LPRIC
Sbjct: 294 GARIIGEFIKDSNQNIFIENGFGGKRVVSPLEVSMLPRIC 333


>UniRef50_P31905 Hydrogenase expression/formation protein hypE n=17 Tax=Bacteria
           RepID=HYPE_RALEH
          Length = 351

 Score =  292 bits (747), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 157/323 (48%), Positives = 206/323 (63%), Gaps = 7/323 (2%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLA 76
           QLI  LF+ AF N WL +  DQA    A  +  G R+  +TD++V+ PLFFPGG+IG L+
Sbjct: 33  QLIQELFVAAFDNEWLRQGNDQA----AFAMPAGARMVMATDAHVVSPLFFPGGDIGSLS 88

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           + GT NDVA++GA P YL+  FILEEG P+  LK +V SMA  AR AG+ IVTGDTKVV+
Sbjct: 89  VHGTINDVAMAGAKPLYLAASFILEEGFPLADLKRIVESMAGAAREAGVPIVTGDTKVVE 148

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGEL 196
           +G  D +FI T G+G +PA I         GD +L+SGT+G+HG  IL+ RE L  D E+
Sbjct: 149 QGKGDGVFITTTGVGVVPAGILIDGAGARPGDAILLSGTMGEHGVAILSKRESLEFDTEI 208

Query: 197 VSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAV 255
            SD A L  L+  +   +PGV+ LRD TRGG+   ++E ++  G G+ L EAA+PV P V
Sbjct: 209 RSDSAALHDLVAQMLAVVPGVRVLRDPTRGGLATTLNEISSQSGVGMVLDEAAIPVLPQV 268

Query: 256 RGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG--VR 313
              CELLGLD L  ANEGKLV       A+ +LAA+  HPLG++A  IGEV+E     V+
Sbjct: 269 DAACELLGLDPLYVANEGKLVAICAAADADALLAAMRGHPLGREARRIGEVIEDGRHFVQ 328

Query: 314 LAGLYGVKRTLDLPHAEPLPRIC 336
           +   +G  R +D    E LPRIC
Sbjct: 329 MRTKFGGMRVVDWLSGEQLPRIC 351


>UniRef50_A4YFA3 Hydrogenase expression/formation protein HypE n=1
           Tax=Metallosphaera sedula DSM 5348 RepID=A4YFA3_METS5
          Length = 352

 Score =  290 bits (744), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 140/351 (39%), Positives = 205/351 (58%), Gaps = 22/351 (6%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           N I L HG+GG  M  LI  +F++   N    E   +   D A +      + F+TDS+V
Sbjct: 8   NVITLLHGAGGTYMHSLIRDVFLKL--NDGFGEVGLEMMDDAAVVNG----IVFTTDSFV 61

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           I P+FF GG+IG+L++ GT ND+A+ G  P+ LS G +LEEG P + L+ +V S+ +TA 
Sbjct: 62  IRPIFFRGGDIGRLSVSGTVNDIAMMGGDPQALSLGVVLEEGFPKDMLEKIVESIKKTAE 121

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN---------------IHWGAQTLTA 166
            A + +VTGDTKV++RG +DK+ INTAG+G  P                        L  
Sbjct: 122 EANVHVVTGDTKVMERGNLDKIVINTAGIGTRPRQLDHNIETLRKSRQPSRWLVPTNLRD 181

Query: 167 GDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGG 226
           GD ++V+GTLGDH   +L+ RE +G +  ++SD A L  +I  L ++ G+   +D TRGG
Sbjct: 182 GDKIVVTGTLGDHAIAVLSSREGVGFESNVMSDVAPLNKMIMNLLEVGGIADAKDPTRGG 241

Query: 227 VNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQ 286
           +  ++ +++   G GI + E+ +PVK  VR   E LG+D L   NEGK V+AV     + 
Sbjct: 242 LADLLQDWSEKSGLGIFIRESDIPVKDEVRAAVEFLGMDVLELGNEGKAVLAVSPEYVKD 301

Query: 287 VLAALHSHPLGKDAALIGEVVER-KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           V+ ALHS PLGKDA +IGEV +  +GV +  + G  R +  P  +P+PRIC
Sbjct: 302 VMDALHSDPLGKDATIIGEVRKDLEGVIMETVVGGNRYVGRPLGDPVPRIC 352


>UniRef50_C3XF65 Hydrogenase expression/formation protein n=3 Tax=Helicobacter
           RepID=C3XF65_9HELI
          Length = 361

 Score =  289 bits (741), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 132/367 (35%), Positives = 202/367 (55%), Gaps = 37/367 (10%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLV-AEGDRLAFSTDS 59
           M+ + LAHGSGG    + +  +FM  F +         A  D       +  +   STDS
Sbjct: 1   MDIVTLAHGSGGINAAEFVQKVFMPYFKD-----LMPYANEDCGIFSSIKDMKYVTSTDS 55

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           Y I+P+FF GGNIGKL +CG++NDVA+ G  P YL+ GFI+EEG  ++ LK +  S+A  
Sbjct: 56  YTINPIFFAGGNIGKLCVCGSSNDVAMMGGKPLYLNIGFIIEEGFNIDLLKQIAESIALE 115

Query: 120 ARAAGIAIVTGDTKVVQRGAVDK------LFINTAGMGAIPANIHWGAQTLTAGDVLLVS 173
            ++  I I++ DTKV+ +           +FINT  +G++  +    A+ L+  D +++S
Sbjct: 116 CKSLNIKILSADTKVLPKVTDSTEAKDKLIFINTTCIGSVEKDC-ISAKNLSENDSIILS 174

Query: 174 GTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVH 232
           G +G HGA I   +  + +   + SDCA L P++++L      + A+RDATRGG+++V++
Sbjct: 175 GKIGSHGARIFLEQNNIAITSNIQSDCASLYPMLESLLQSNIPIHAMRDATRGGLSSVLN 234

Query: 233 EFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALH 292
           E+A +    I++ E  + +   V GVCE+LGL+  + ANEG  VIA+ +  AE+VL+ L 
Sbjct: 235 EWAISSHACIDIYEEKIQIDSEVHGVCEMLGLEPYDLANEGVCVIAMPKQYAEEVLSLLR 294

Query: 293 SHPLGKDAALIGEVVE-----------------------RKGVRLAGLYGVKRTLDLPHA 329
            H LG +A +IGEV +                        + V L   YG KR L+ P  
Sbjct: 295 GHTLGVNATIIGEVSKVFNPIFNLQDSKDNKAQISKTTYHQKVVLHTKYGSKRFLEYPQG 354

Query: 330 EPLPRIC 336
           E LPRIC
Sbjct: 355 ELLPRIC 361


>UniRef50_A7I1Q2 Hydrogenase expression/formation protein HypE n=24
           Tax=Epsilonproteobacteria RepID=A7I1Q2_CAMHC
          Length = 390

 Score =  287 bits (736), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 148/391 (37%), Positives = 209/391 (53%), Gaps = 59/391 (15%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEG----------- 50
             I L+HG GG+ M  LIN    +AF N  L    D A L+    + +            
Sbjct: 3   KQILLSHGGGGEEMNSLINDTIFKAFDNEILRRANDSAILNFPLDLDKNFDIISANFGDK 62

Query: 51  ------------------------------------------DRLAFSTDSYVIDPLFFP 68
                                                       LAF+TDS+V+ PLFF 
Sbjct: 63  TDYFNEKSQNFDVSNLNGQNKTDNMNFNVQNCHNKKNTQILCGNLAFTTDSFVVTPLFFN 122

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
           GG+IGK+A+CGT ND+A+ GA P +LSC FI+EEGL ++T + ++ SMA+TA+ AG+ IV
Sbjct: 123 GGDIGKIAVCGTVNDLAMVGAKPLFLSCAFIIEEGLEIDTFERILNSMAKTAKEAGVKIV 182

Query: 129 TGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
            GDTKVV RG+ D++FINT+G+G I          +  G  +L+SG +G HGA I+  R+
Sbjct: 183 CGDTKVVPRGSGDQIFINTSGIGQILKAG-VQMDCVKKGAKVLISGDIGRHGAVIMAARD 241

Query: 189 QLGLDGELVSDCAVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           ++ +  +L SDC  L   + + L++   + ALRDATRGG++AV++EFA    C I + E 
Sbjct: 242 EISVSTDLKSDCKPLNAAVTELLKNDVKILALRDATRGGLSAVLNEFAQHLNCEISIREN 301

Query: 248 ALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
            + V P V G+CELLG +  + ANEG  V  +E     + L  L      ++AA+IGEV 
Sbjct: 302 DIKVAPEVLGICELLGFEPYDLANEGTFVAFIEDGDEIKALEILRK--FNENAAIIGEVT 359

Query: 308 --ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
             E+  V L   YG +R L+ P  E LPRIC
Sbjct: 360 QNEKGRVILQNAYGTERFLEFPKGELLPRIC 390


>UniRef50_C9LR03 Hydrogenase expression/formation protein HypE n=1 Tax=Dialister
           invisus DSM 15470 RepID=C9LR03_9FIRM
          Length = 327

 Score =  287 bits (735), Expect = 5e-76,   Method: Composition-based stats.
 Identities = 140/335 (41%), Positives = 196/335 (58%), Gaps = 10/335 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            I L HGSGG+   +LI  +F   F +  L + ED      A L         ++DS+V+
Sbjct: 2   KITLKHGSGGEESGRLIKDIFASVFDDEILLKMEDS-----AVLPPLHGNPVLTSDSFVV 56

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           +PLFF GG+IGKL++CGT ND++  GA P YL+  FILE GL  + L  +V SM ETA  
Sbjct: 57  EPLFFKGGDIGKLSVCGTVNDLSSMGARPLYLTASFILETGLDTDILGKIVQSMKETAEE 116

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ IV GDTKV++      L+INTAG+G  P++     + + +GD L+++GTLGDH A 
Sbjct: 117 AGVRIVAGDTKVIEGKG--GLYINTAGVGERPSSRDISCRNMKSGDTLILTGTLGDHHAA 174

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCG 241
           +L  R  LG++ E+ SDCA L  +++ L +    V  +RD TRGG+  V +E A +    
Sbjct: 175 VLTNR--LGIESEIESDCAPLNHMVEELLEGNISVHTVRDITRGGLATVANELAVSSSVR 232

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IEL E  +PV   V+G   +LGLD L   NEGK++IAV    AE+ +  L  +  G++A 
Sbjct: 233 IELEEELIPVSDIVQGFTGILGLDPLTMGNEGKMIIAVSPKDAEKAVGILRRNKYGRNAV 292

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
             G+V+E KGV L    G  R +     E LPRIC
Sbjct: 293 AAGQVLEGKGVYLRTALGGLRRVLPLRGEGLPRIC 327


>UniRef50_D1BLS0 Hydrogenase expression/formation protein HypE n=4
           Tax=Veillonellaceae RepID=D1BLS0_VEIPT
          Length = 335

 Score =  287 bits (734), Expect = 5e-76,   Method: Composition-based stats.
 Identities = 155/340 (45%), Positives = 212/340 (62%), Gaps = 9/340 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  ++L HG+GG+   +L +   ++ F N  LA   D      AQ      R+AFSTDSY
Sbjct: 1   MERVRLVHGNGGRFSHELTDRFILKYFTNDLLAPLHDG-----AQFPVTAGRMAFSTDSY 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FFPGGNIGKLA+CGT ND+A++GAIP+YLSCG ILEEGL  E L  ++ +M+E A
Sbjct: 56  VVQPAFFPGGNIGKLAVCGTVNDLAMNGAIPQYLSCGLILEEGLAFEELDEILRTMSEMA 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +AA + IVTGDTKVV++G VDK++INTAG+G IP  I  G   + AG  +++SG +GDH 
Sbjct: 116 KAANVQIVTGDTKVVKKGEVDKIYINTAGIGMIPDGIDIGPHRVKAGLDIILSGAIGDHS 175

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAAC 238
             ++  R  L L   L +DCA L  ++Q + D  G  V  LRD TRGG+  V+ E A   
Sbjct: 176 IAVMGQRFGLDLSDSLTTDCAPLNKMVQAVLDKVGTQVALLRDPTRGGLGTVLKEIADQS 235

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GI++ E A+P+   V+ VC +LG D L  ANEGK+V+ VE +   +VL  LHS   G 
Sbjct: 236 QVGIKVEETAIPIHEEVQSVCNILGYDPLYLANEGKVVLIVEPSITNEVLKILHSFKEGS 295

Query: 299 DAALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           +A LIG+ +++    V L    G  R +DL   + +PRIC
Sbjct: 296 EAVLIGKTIDKNIGKVGLQTAIGGVRLIDLLGEDQVPRIC 335


>UniRef50_UPI0001C42969 hydrogenase expression/formation protein HypE n=1 Tax=Bacillus
           pseudofirmus OF4 RepID=UPI0001C42969
          Length = 334

 Score =  286 bits (733), Expect = 7e-76,   Method: Composition-based stats.
 Identities = 146/341 (42%), Positives = 207/341 (60%), Gaps = 13/341 (3%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           +  I LAHG GG+   QLI  +FM AF++        + + D A    EG R+A +TDSY
Sbjct: 2   VQRISLAHGEGGELTHQLIQEVFMSAFSSKK------EIQHDSAVFPIEGKRIAVTTDSY 55

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P+FFPGGNIGKLAI GT ND+AV  A+P+ ++ GFILEEG  +  L  +V SMAE A
Sbjct: 56  VVQPIFFPGGNIGKLAITGTVNDLAVCCAVPKMITAGFILEEGFALSDLNKIVHSMAEEA 115

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +AA + IV GDTKVV++G+ D +FINT G+GAI       +  +  GD ++VSGT+GDHG
Sbjct: 116 KAANVKIVAGDTKVVEKGSADGIFINTTGIGAISEQ--VCSPAIKKGDCVVVSGTIGDHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACG 239
             IL+ R QLGL  ++ SDCA L  LIQ+L + + G++ +RD TRGG+   + E      
Sbjct: 174 IAILSARNQLGLLTDVQSDCASLHSLIQSLLEQVDGIRLMRDPTRGGLATSLVELCEDFQ 233

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             +EL E  +P++  V G C +LG D L  ANEGK+VI  +    ++V+  + +H  G++
Sbjct: 234 FSVELEEDLIPIRREVTGACNILGFDPLYLANEGKVVIVCDSTNKDKVIEIMQNHKYGEE 293

Query: 300 AALIGEVV----ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A +IG+V+        +      G  R +   +   LPRIC
Sbjct: 294 AKVIGKVISVNDSNGKLYSRTQIGTTRRIHRLNGMILPRIC 334


>UniRef50_A8A9S1 Hydrogenase expression/formation protein HypE n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8A9S1_IGNH4
          Length = 337

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 123/339 (36%), Positives = 187/339 (55%), Gaps = 8/339 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLA-EQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           ++ LA G GG+  ++ I +  +  F    L     D      A  + +   L  S DSY 
Sbjct: 2   SVTLAVGGGGRETEEFIKNFILPLFKIRSLGSVGLDDLEDGAAVPIGDNKYLVVSVDSYT 61

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P FFPGG+IGKLA  G+ NDVAV GA P+ L    I+EEG  +  LK ++ SM+E   
Sbjct: 62  VSPPFFPGGDIGKLAATGSLNDVAVMGAEPKALMDAIIVEEGFKLSDLKTILKSMSEVTN 121

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           +  +A++ GDTKV+ +G+VDK+ I+T G+G               GD +LV+G +GDHGA
Sbjct: 122 SLNVALLGGDTKVMPKGSVDKIVISTVGIGIAEGP-LLTLDRGEPGDKVLVTGPVGDHGA 180

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACG 239
           TIL L+  L +   L SD   + P ++ LR+  G  +KA +D TRGG+   ++E A    
Sbjct: 181 TILALQFGLQVKT-LKSDVRPVWPAVKALREALGEDLKAAKDPTRGGLAMALNELAERSK 239

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             + + EA +P++ AV+   E+LG++ L  A+EG+ V  V+ + AE+ L  L      ++
Sbjct: 240 TTVYVEEARVPIREAVKEYAEMLGVEPLALASEGQAVFVVKGDRAEEALEVLRKAGF-EE 298

Query: 300 AALIGEVVERKGVRL--AGLYGVKRTLDLPHAEPLPRIC 336
           AA+IGE+ + K   +      G  R L+ P  E +PRIC
Sbjct: 299 AAIIGELRKGKPGYVISRTPVGGLRLLEKPSGELVPRIC 337


>UniRef50_B5YJH9 Hydrogenase expression/formation protein HypE n=1
           Tax=Thermodesulfovibrio yellowstonii DSM 11347
           RepID=B5YJH9_THEYD
          Length = 332

 Score =  282 bits (721), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 141/339 (41%), Positives = 202/339 (59%), Gaps = 10/339 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ I L HGSGG+ M +LI       F  P L    D A       +    ++A +TDSY
Sbjct: 1   MDKILLGHGSGGKLMYELIKKYIAPIFELPSL---MDSAI----VSLNHSGKIAITTDSY 53

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IG LAI GT ND+AV GA+P YL+ GFILEEG P+   + +++S++ +A
Sbjct: 54  TVSPIFFPGGDIGDLAINGTVNDLAVVGAVPLYLTVGFILEEGFPLSDFEKILSSISSSA 113

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           + AG+ IV GDTKVV +G  D +FINT+G+G IP  +      +  GD +L+SG++G+HG
Sbjct: 114 KKAGVKIVAGDTKVVDKGKGDGIFINTSGIGVIPEGVELSPLKIEMGDKILISGSIGNHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRD--IPGVKALRDATRGGVNAVVHEFAAAC 238
             +++ R     +  ++SD   L  LI  +     P VK +RD TRGG+   + E A   
Sbjct: 174 IAVMSERNGFTFEPPVLSDTRALNGLIDQIMKEFTPFVKVMRDPTRGGLATTLKELALES 233

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
              I + E+A+P+   V+G CELLGLD L  ANEG  V  V+ + AE++L  + SHP G+
Sbjct: 234 LKDILIYESAIPLHDTVKGACELLGLDPLYVANEGIFVAIVKADVAEKILQLMKSHPFGE 293

Query: 299 DAALIGEVV-ERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           ++A+IGEV  +   V L    G  R +D+   E LPRIC
Sbjct: 294 ESAIIGEVTGKGGKVLLKTFIGGTRIVDMLPGEQLPRIC 332


>UniRef50_C1SLC8 Hydrogenase expression/formation protein HypE n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SLC8_9BACT
          Length = 327

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 140/336 (41%), Positives = 198/336 (58%), Gaps = 9/336 (2%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  I +A GSGG + +  ++ +      N  L +  D A +      +   R AF+TDSY
Sbjct: 1   MEKITMAVGSGGTSSRSFVSEIIFSRLGNEHLLKASDAAIV------STSGRTAFTTDSY 54

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V+ P FFPGGNIGK+A+CGT ND+ VSGA P YLS G I+ EG P+  L+ V+ SMAE  
Sbjct: 55  VVRPEFFPGGNIGKIAVCGTINDLLVSGAKPLYLSFGLIMPEGYPVADLERVIDSMAEEC 114

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           R A + IV GDTKVV +G  D L INT+G+G    + +     +  GD ++++  +  HG
Sbjct: 115 RKADVKIVCGDTKVVDKGGCDGLIINTSGIGESLRD-YTEPYNIQEGDAVILTSDVARHG 173

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
            +++  R +LG DGE++SDCA L  +   + ++  VK  RDATRGGV AV++E A+  G 
Sbjct: 174 MSVMLARGELGFDGEVLSDCACLKDVFSAVENL-NVKFARDATRGGVAAVLNEIASDSGK 232

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G  + E  +P+   V  +C++LG D L  ANEG  VI V    AE+ L+ + +   G+ A
Sbjct: 233 GFLMRETDIPMDENVGYLCDMLGFDPLAVANEGLAVIIVSEEDAEKALSNICACENGQRA 292

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A+ G V E K V L    G KR +++P  E LPRIC
Sbjct: 293 AIAGRV-EGKNVILETSIGGKRHIEMPAGELLPRIC 327


>UniRef50_C7NVH7 Hydrogenase expression/formation protein HypE n=1 Tax=Halorhabdus
           utahensis DSM 12940 RepID=C7NVH7_HALUD
          Length = 365

 Score =  281 bits (720), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 133/341 (39%), Positives = 196/341 (57%), Gaps = 10/341 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSL----FMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFST 57
             I  AHG+GG  M +L++++    F +A A+  LA  +D +     Q + +   +  +T
Sbjct: 29  EVITHAHGAGGGQMTELVDAVAVSQFADAAADVGLAALDDGSV----QPIDDDHSVVVTT 84

Query: 58  DSYVIDPLFFPGGNIGKLAICGTANDVAVSGA-IPRYLSCGFILEEGLPMETLKAVVTSM 116
           DS+V+ PLFF GG+IG+LA+ GT ND+A+ GA  P  L+   I+E G P  T++ V  SM
Sbjct: 85  DSHVVTPLFFRGGDIGRLAVSGTVNDLAMMGATEPLALTSSLIIEAGTPQTTVERVTESM 144

Query: 117 AETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTL 176
            E    AG  + TGDTKV+  G +D L INT G+  +P   H     L+ GD L+VSGT+
Sbjct: 145 REACEEAGATVTTGDTKVMGSGEMDTLAINTTGVAVVPKGGHVPDAGLSVGDRLIVSGTV 204

Query: 177 GDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAA 236
           GDHG ++L+ RE     G+L SD   +  L++   D   V A++D TRGG+  V++E A+
Sbjct: 205 GDHGISLLSEREGFDFGGDLESDVQPVNDLVRAAMDAGEVTAMKDPTRGGLATVLNEMAS 264

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
               GI++ E ++PV   V    E+LG++  + A EG +V+ V    A  VL AL  +P 
Sbjct: 265 KADVGIDVEERSVPVSGPVSSAGEVLGIEPFDVACEGVVVMGVASEDAADVLDALRDNPK 324

Query: 297 GKDAALIGEVVERK-GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           G+DAA++GEVV+   G  +      +R L  P  E LPRIC
Sbjct: 325 GEDAAIVGEVVDDHTGQVVLDTGFGRRYLSPPEGEQLPRIC 365


>UniRef50_D2LQB8 Hydrogenase expression/formation protein HypE n=3
           Tax=Aciduliprofundum boonei T469 RepID=D2LQB8_9EURY
          Length = 339

 Score =  280 bits (718), Expect = 4e-74,   Method: Composition-based stats.
 Identities = 114/343 (33%), Positives = 194/343 (56%), Gaps = 13/343 (3%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           ++ I++  G+GG+AM++LI  + ++        +       D A +  +G+ + F+ D +
Sbjct: 3   LDRIRMVDGAGGEAMERLIKEIILDNITLRSAGKVSLDDLDDGATISLDGEDIVFTIDGH 62

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+FFPGG+IGKLA+ GT ND+AV GA P  L+   I+E+G  M++LK ++ S+ +T 
Sbjct: 63  TVKPIFFPGGDIGKLAVSGTVNDLAVMGAKPLALAISLIIEDGFSMDSLKNIMISIDKTG 122

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGM--GAIPANIHWGAQTLTAGDVLLVSGTLGD 178
           +   + I+TGDTKVV+        I    +  G   A+          GD +L++G +G+
Sbjct: 123 KDVPVPIITGDTKVVED------KIGIFAISAGIGKADKIVRDSGARVGDFVLINGGIGE 176

Query: 179 HGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG---VKALRDATRGGVNAVVHEFA 235
           HG  I++ RE +  +  LVSD + L  LI+ +    G   + A++D TRGG++  ++E A
Sbjct: 177 HGFAIMSKREGIDFETSLVSDVSPLWSLIEDVAKCIGWENIHAMKDPTRGGLSEALNEMA 236

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
           +    GIE+ E ++P+K +V+   E+LG+     ANEGK+V+ V     +  + A+  + 
Sbjct: 237 SKANVGIEIDEESVPIKSSVKAASEMLGISPFIMANEGKVVMIVADGYQDDAIEAMRKNK 296

Query: 296 LGKDAALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            GKDAA+IG V+      V +    G KR ++ P  +P+PR+C
Sbjct: 297 NGKDAAIIGRVIREYPGKVIIKTKIGGKRFIERPIGDPVPRVC 339


>UniRef50_B4S328 Hydrogenase expression/formation protein HypE n=2
           Tax=Proteobacteria RepID=B4S328_ALTMD
          Length = 350

 Score =  277 bits (710), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 140/339 (41%), Positives = 200/339 (58%), Gaps = 10/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
            +IQLA G+GG   ++LI+ +F            +     D A +  +G  L+ +TDS+V
Sbjct: 18  ESIQLAQGNGGTLTKRLIDHVFKNKANK------DLDLLHDAATVTFDGPYLSITTDSFV 71

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P  FPGGN+G L++ GT ND+AV GA PRY+S  FI+EEG  + TLK +V  M + A 
Sbjct: 72  VSPPTFPGGNVGALSVYGTVNDLAVVGATPRYISTAFIIEEGFSLSTLKQIVNGMHQAAE 131

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
              +AIVTGDTKVV +G+   +FINT G+G       W    + AGD +LVSG++GDHGA
Sbjct: 132 ETKVAIVTGDTKVVPKGSGGGVFINTTGVGDSRDAPIWDTSLIKAGDHVLVSGSVGDHGA 191

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            +L  RE  GL G+L SDC  + PLI  ++ + GV+ +RD TRGG++ ++H+ A   G  
Sbjct: 192 CVLLAREDYGLQGQLKSDCGSVVPLIDPIKHLEGVRFVRDPTRGGLSVLLHDVANETGFD 251

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IEL E  +PV+P V  VCE+LG D    A EG++V  V  + + +VL    S   G+ A 
Sbjct: 252 IELIENNIPVRPEVASVCEILGFDPFVLACEGRIVAVVAPDISGKVLEHWRSIRNGEQAE 311

Query: 302 LIGEVVE----RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            IG +V+    +  V +    G +R ++    EPLPRIC
Sbjct: 312 HIGVIVKNTESKGRVTIVTPMGGRRFMNELEDEPLPRIC 350


>UniRef50_Q8NKU8 Membrane-bound NiFe hydrogenase n=1 Tax=Acidianus ambivalens
           RepID=Q8NKU8_ACIAM
          Length = 339

 Score =  277 bits (708), Expect = 5e-73,   Method: Composition-based stats.
 Identities = 121/343 (35%), Positives = 183/343 (53%), Gaps = 15/343 (4%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARL--DLAQLVAEGDRLAFSTDS 59
           N IQ++HG+GG+  QQL+  LF           +        D   ++     L  +TDS
Sbjct: 4   NKIQISHGNGGKETQQLLQRLFFSRLPLELKRVKGGVGIDYPDDGAVLQNN--LVVATDS 61

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           + ++P FFPGG+IG LA+ GT NDV + GA P  +    ++ EG P++ L+ +  SM E 
Sbjct: 62  HTVNPYFFPGGDIGYLAVSGTLNDVIMMGAKPIAMLDSIVVSEGFPIDDLEKITGSMIEL 121

Query: 120 ARAAGIAIVTGDTKVVQRGAV-DKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD 178
            +   I +V GD KV++  A+ + + INT G+G +          +  GD ++V+G +G 
Sbjct: 122 LKKYNIPLVGGDFKVIEETAMKNSIIINTVGLGVVETGSPI-VDAIKPGDKIIVTGPVGV 180

Query: 179 HGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAA 237
           HGA I  ++    +   L SD   L  L++      G V A RD TRGG+ A ++E+A  
Sbjct: 181 HGAVIAAMQYN--ISTNLKSDVRPLFELLEVFSKFKGYVHAARDPTRGGLAATLNEWAQL 238

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
            G  I + EA +PV   V+ + E+ GLD LN A+EG  V+AV+ N  + VL  L S  LG
Sbjct: 239 TGNVIVIEEAKVPVLEDVKAITEVTGLDPLNLASEGVGVLAVDSNVEDDVLETLKS--LG 296

Query: 298 KDAALIGEVVE---RKGVRL-AGLYGVKRTLDLPHAEPLPRIC 336
            + A IG VVE    KG+ +     G  + L++P  + +PRIC
Sbjct: 297 FEPASIGYVVEPKSEKGIVVAKTAVGGAKILEMPTGDIVPRIC 339


>UniRef50_A7H7N3 Hydrogenase expression/formation protein HypE n=1
           Tax=Anaeromyxobacter sp. Fw109-5 RepID=A7H7N3_ANADF
          Length = 340

 Score =  276 bits (707), Expect = 6e-73,   Method: Composition-based stats.
 Identities = 155/338 (45%), Positives = 203/338 (60%), Gaps = 8/338 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            I L HGSGG+AM+QLI  +F+   A+P        A  D A +      L  +TDS+V+
Sbjct: 7   KIGLKHGSGGRAMRQLIEDVFL-TLASPVDGIG-LSALDDGAAIRVGDRWLVVTTDSHVV 64

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGA-IPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
            P+FFPGG+IG+L++ GT ND+A+ GA  P  L+C  +LE+G P   L+ VV SM ETAR
Sbjct: 65  HPIFFPGGDIGRLSVSGTVNDLAMMGATEPLGLTCAVVLEDGFPRADLERVVASMRETAR 124

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            A   IVTGDTKV+ +  VD + +NT   G   A        L AGD+L+V+GT+GDHG 
Sbjct: 125 EANAPIVTGDTKVMGKDEVDGIVLNTT--GVALAERVVSDAGLRAGDLLIVTGTIGDHGM 182

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACG 239
            I++ R  L L+G+L SD A L  L++      G  V A++D TRGGV  V+HE AA   
Sbjct: 183 AIMSRRHDLRLEGDLRSDVAPLNGLVREALRAGGEDVVAMKDPTRGGVAGVLHEMAAKGK 242

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            GI + E ALPV+  VR   E++G+D L  ANEGK VIAV   AA++VLAAL +HPLG  
Sbjct: 243 VGIVIDETALPVRDEVRAAGEMIGIDPLLVANEGKAVIAVRARAADKVLAALRAHPLGAS 302

Query: 300 AALIGE-VVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A +I   + ER G  +      KR L  P  E LPRIC
Sbjct: 303 ATVIATAIAERPGAVILDTGFGKRMLAEPEGELLPRIC 340


>UniRef50_C8PGA7 Hydrogenase expression/formation protein HypE n=1 Tax=Campylobacter
           gracilis RM3268 RepID=C8PGA7_9PROT
          Length = 395

 Score =  275 bits (704), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 154/397 (38%), Positives = 209/397 (52%), Gaps = 66/397 (16%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARL--DLAQ-------------L 46
             I L+HG GG+ M +LIN +   AF N  L    D A L  D                 
Sbjct: 3   ETILLSHGGGGEEMNRLINEMIFAAFDNEILRANNDSAILNLDAGAGFDRTAPSSALNSA 62

Query: 47  VAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPM 106
            + G  LAFSTDS+V+ PLFF GG+IGK+A+CGT ND+A+ GA P +LSC  I+EEGL +
Sbjct: 63  ASFGGELAFSTDSFVVTPLFFNGGDIGKIAVCGTVNDLAMVGAKPLFLSCALIIEEGLSL 122

Query: 107 ETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTA 166
             L+ ++ SMA TAR+ G+ +V GDTKVV RG  DK+FINT+G+G +        Q + A
Sbjct: 123 SELRRILDSMASTARSCGVRVVCGDTKVVPRGKCDKIFINTSGIGRVLRPARV--QNIKA 180

Query: 167 GDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRG 225
           G  +L+SG +G HGA IL +R+++ L  EL SDC  L   ++ L      ++A+RDATRG
Sbjct: 181 GAKILLSGDIGRHGAVILAVRDEIALSSELQSDCKPLCAAVEELILQGVKIQAMRDATRG 240

Query: 226 GVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERN-AA 284
           G++AV++EFA++ G    + E  + +   V GVCELLG +    ANEG  V  VE +  A
Sbjct: 241 GLSAVLNEFASSSGLEFLVREEDIKISDEVVGVCELLGFEPYELANEGTFVAIVEDDAEA 300

Query: 285 EQVLAALHSHPLGKDAALIGEVVE------------------------------------ 308
            + L  L       +AA+IGEV E                                    
Sbjct: 301 NRALEILRE--FDANAAIIGEVREVGHDKGEFKGSLAPKLGTWDESTGASDAGTVSENRA 358

Query: 309 ---------RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
                    +  V L   YG +R L+LP  E LPRIC
Sbjct: 359 GQFQTPHATKGRVILQNAYGSQRFLELPKGELLPRIC 395


>UniRef50_A6C222 Hydrogenase expression/formation protein HypE n=1 Tax=Planctomyces
           maris DSM 8797 RepID=A6C222_9PLAN
          Length = 358

 Score =  274 bits (702), Expect = 2e-72,   Method: Composition-based stats.
 Identities = 156/339 (46%), Positives = 205/339 (60%), Gaps = 9/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           + + LAHG GG+  ++LI         N +L   +D ARL           LAF+TDS+V
Sbjct: 25  DCVTLAHGEGGRLSRKLIQERIASVLKNEFLETSDDAARL-----PRVDGPLAFTTDSFV 79

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG+IG LAI GT ND+AVSGA P +L+   ILEEG P+  L  V+ S+AE A 
Sbjct: 80  VSPLFFPGGDIGSLAIYGTVNDLAVSGAHPLWLTLSLILEEGFPLMLLDRVLQSLAEAAS 139

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           +  + IV GDTKVV RGAVD LFINTAG+G +   +  G   L  GD L+VSG +G HG 
Sbjct: 140 STAVKIVAGDTKVVPRGAVDGLFINTAGVGKLTEPVPPGPAFLREGDELVVSGPIGQHGI 199

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAACG 239
            +L  REQL LD    SDC  L   ++ LR+  G  +  LRDATRGGV AV+ E+A + G
Sbjct: 200 AVLAAREQLQLDPLPHSDCGSLLTAVEQLREALGDRICCLRDATRGGVAAVLQEWAGSSG 259

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             + + E  +PV P V+G+ ELLGLD L+ ANEG ++IAV + A ++ ++ L S     D
Sbjct: 260 LTLSIDERCVPVTPGVKGMSELLGLDPLHIANEGTMLIAVRQGAGQEAVSVLQSLSKTAD 319

Query: 300 AALIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A LIG V  R    V +    G+++ L  P   PLPRIC
Sbjct: 320 ARLIGSVKGRGVAAVTVKRTLGLEQPLHDPLGSPLPRIC 358


>UniRef50_C9KK60 Hydrogenase expression/formation protein HypE n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KK60_9FIRM
          Length = 348

 Score =  272 bits (696), Expect = 1e-71,   Method: Composition-based stats.
 Identities = 151/340 (44%), Positives = 196/340 (57%), Gaps = 9/340 (2%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG+GG+    LI  +F   F NP     +D A L +        R AF+TD +++
Sbjct: 12  RVTLAHGAGGRQTAALIARVFARHFQNPDF-TADDAAILPVG--NFATGRTAFTTDGFIV 68

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
            P  FPGGNIGKL+ICGT ND+A  GA+PRYLSC F +EEG P+  L A+  +MAETA+A
Sbjct: 69  SPWQFPGGNIGKLSICGTVNDLACMGAVPRYLSCAFQIEEGFPLRDLDAIAAAMAETAKA 128

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ IV GDTKV  RG VD +FI T G+G +  +         AGD ++V+G +G HGA 
Sbjct: 129 AGVRIVAGDTKVAGRGQVDGVFITTTGLGELLPDAEPSGSRAEAGDAIIVTGDVGRHGAA 188

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDI----PGVKALRDATRGGVNAVVHEFAAAC 238
           IL  R    +D  + SDCA L   ++ L         +  +RDATRGGV  V+HE AA  
Sbjct: 189 ILVARRDFAIDAAITSDCAPLAATVRALFAAVPDKSAIHTIRDATRGGVGTVLHEIAAES 248

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             GIEL   A+PV P VRGVC LLGL+ L  A EG+LV+   +  A +++  L + P  +
Sbjct: 249 HVGIELDAPAIPVAPEVRGVCGLLGLEPLYLACEGRLVLFAPQAIAPKLVETLRALPDSR 308

Query: 299 DAALIGEVVER--KGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            AA+IG V       V L    G K  L  P  E LPRIC
Sbjct: 309 QAAIIGHVTPDFSGRVVLRTEIGTKTLLPEPSGELLPRIC 348


>UniRef50_B2KBC5 Hydrogenase expression/formation protein HypE n=1
           Tax=Elusimicrobium minutum Pei191 RepID=B2KBC5_ELUMP
          Length = 335

 Score =  268 bits (686), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 139/339 (41%), Positives = 198/339 (58%), Gaps = 10/339 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           N I LAHG+G +  +  I    ++ F +  LAE  D      A++      + F+TDSYV
Sbjct: 3   NKITLAHGAGAEVSRGFIKKTLLKYFKSKSLAELSDS-----AKIKINSKDILFTTDSYV 57

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           ++P+FFPGGNIG LA+CGT ND++VSG   +Y+S G I+EEGL ++ L+ ++ ++A  A+
Sbjct: 58  VNPVFFPGGNIGDLAVCGTVNDISVSGGDIKYISLGLIIEEGLDLKELEQILKAVALRAK 117

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
            AG+ IVTGDTKVV+RG  DK+FINT+G+G   A+    A+ +  GD ++VSG L +HG 
Sbjct: 118 EAGVEIVTGDTKVVERGGADKIFINTSGIGQAIADATVKARNIKKGDKIIVSGNLAEHGI 177

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHEFAAACG 239
           +++N R +LGL G L SD A L  + +   L+    +   RD TRGG+   + E A    
Sbjct: 178 SVMNERHKLGLKG-LKSDVAPLNKITKALFLKFDKDIHMTRDLTRGGLAGALKEIAEQAK 236

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             IEL E+ +P+  AV+G   +LG+D L  ANEGK V   +   AE VL  L +   GKD
Sbjct: 237 KDIELEESRVPLSKAVKGAVSILGVDPLQTANEGKFVCIADAKKAESVLKLLKTFAYGKD 296

Query: 300 AALIGEV--VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A + G V    +  V +    G  R L       LPRIC
Sbjct: 297 AKICGTVLKTRKGRVYIKTPLGASRALAEHEGSNLPRIC 335


>UniRef50_D1VJK8 Hydrogenase expression/formation protein HypE n=1 Tax=Frankia sp.
           EuI1c RepID=D1VJK8_9ACTO
          Length = 409

 Score =  265 bits (679), Expect = 1e-69,   Method: Composition-based stats.
 Identities = 166/384 (43%), Positives = 218/384 (56%), Gaps = 54/384 (14%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
            +I +AHG+GG+A   L++++F+EAF NP L   +D A +D       G RL  +TDSYV
Sbjct: 31  EHITMAHGAGGKATAALVDAVFLEAFRNPALEALDDGAHVDAG-----GARLVLTTDSYV 85

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + PLFFPGG IG LA+ GT ND+AV GA P YL+CGF+LEEG  +  L+ VV +MAE AR
Sbjct: 86  VTPLFFPGGCIGDLAVNGTVNDLAVCGAKPLYLTCGFVLEEGFAVADLRRVVAAMAEAAR 145

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPAN------------------------- 156
            AG+ +VTGDTKVV RG  D  ++NT G+G                              
Sbjct: 146 TAGVTLVTGDTKVVPRGRADGCYVNTTGLGLFHPGGSTLDDESPMEGVVAADDPVGPWPV 205

Query: 157 ---------------IHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCA 201
                             G      GDV+LVSG +GDHG TI+  R +L L+ +L SD A
Sbjct: 206 GYTPPGHRPTEPDRLDRLGMAHARPGDVVLVSGPIGDHGITIMLARGELDLEADLRSDTA 265

Query: 202 VLTPLIQTLRDI-------PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
            L+ L++ L           GV+A+RDATRGGV  V++E A A G G+ + E A+PV+ A
Sbjct: 266 PLSGLVERLLTATSGPEHGGGVRAMRDATRGGVATVLNELAMAAGVGVVIDEDAVPVREA 325

Query: 255 VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG--V 312
           VRG  ELLG+D L  A EG+LV  V   AA+  LAAL + PLG  A +IG VV+     V
Sbjct: 326 VRGAAELLGIDPLYVACEGRLVAVVAPEAADAALAALLADPLGAGATVIGRVVDDPPGLV 385

Query: 313 RLAGLYGVKRTLDLPHAEPLPRIC 336
            L   +G  R +D+   +PLPRIC
Sbjct: 386 LLNTAFGGTRIVDMLVGDPLPRIC 409


>UniRef50_B5Y920 Hydrogenase expression/formation protein HypE n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y920_COPPD
          Length = 319

 Score =  264 bits (676), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 129/337 (38%), Positives = 193/337 (57%), Gaps = 19/337 (5%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M+ I L+ G+GG+ M Q +                      D A +    +  AF+ DS+
Sbjct: 1   MDKITLSIGTGGEEMTQFLQKTVFPILEE--------SISGDAALV----NHTAFTIDSF 48

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
           V +P FFPGG+IG LA+ GT ND+  +GA P  L+   ILEEGL ME ++ ++    ETA
Sbjct: 49  VAEPPFFPGGSIGTLAVSGTVNDLVAAGAKPSALALSLILEEGLDMEVVRRILQDAKETA 108

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           + A I IVTGDTKVVQ+GA DK+F+ T+G+G          ++   GD ++V+G +  HG
Sbjct: 109 KLAQIKIVTGDTKVVQKGAADKVFVTTSGIGQ----KVLDFESPAPGDAVVVTGDIARHG 164

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACG 239
           AT+L   ++  L+ +L SDC  L  LI  L+   G +K +RD TRGGV  ++HEF +   
Sbjct: 165 ATMLLASKKFELESQLTSDCEPLCWLIDVLKPFEGFLKWMRDPTRGGVGTILHEFCSQFS 224

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            G+ L +  +P+ P V+G+CELLGL+ L+ A+EG++VI +  + A + L +L   P   +
Sbjct: 225 LGVRLFQKQIPIMPEVKGICELLGLEPLHLASEGRMVIVISPDKAHEFLESLK--PFAPN 282

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           A++IGEVV+        + G +  +     E LPRIC
Sbjct: 283 ASVIGEVVDDHKTLTQVVDGYETYVPPLTGEILPRIC 319


>UniRef50_B6YVE6 HypE n=9 Tax=Thermococcaceae RepID=B6YVE6_THEON
          Length = 330

 Score =  264 bits (675), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 82/334 (24%), Positives = 140/334 (41%), Gaps = 19/334 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQ-ARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+   + +  +       P           +D   +      L  STD     P+     
Sbjct: 5   GKIPPEKLREIVFNRLGAPGERVIAKSDLGVDATAIDFGSSVLVASTD-----PITGAEE 59

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            IG  A+   ANDVA  GA P++     +L E      L  ++  + E+A   G+AIV G
Sbjct: 60  KIGFYAVHINANDVATFGAKPKWFLVSILLPENSDDALLVKIMDELHESASKLGVAIVGG 119

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T+V     +D+  +    +G +P      +     GD ++++   G  G  I+      
Sbjct: 120 HTEVTP--GLDRPIVAGTMLGEVPKEKLVTSNGAKPGDAIILTKWAGLEGTAIIASERGK 177

Query: 191 GLDG----ELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGCG 241
            L+     E V     L  +I  + D       GV A+ D T GGV   +HE A A   G
Sbjct: 178 ELEKAFGKEFVEKAQSLIEMISVVEDALTANEIGVNAMHDPTEGGVANGLHEMADAAKLG 237

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             +    +P++     +CE   L+ L   + G L+IA  +  A+ +++AL     G +A+
Sbjct: 238 FRVYAERIPIRKETLKICEFYDLNPLALISSGALMIAAPKEKADSIISALKRK--GINAS 295

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           +IGE +E K  R+    G ++ L+ P ++ L ++
Sbjct: 296 VIGEFLEDKESRVMVDNGKEKPLERPESDELWKV 329


>UniRef50_A4TCL4 Hydrogenase expression/formation protein HypE n=15 Tax=Bacteria
           RepID=A4TCL4_MYCGI
          Length = 373

 Score =  262 bits (671), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 142/326 (43%), Positives = 191/326 (58%), Gaps = 8/326 (2%)

Query: 14  AMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIG 73
              +L+  LF+ AF +   A   D      A +   G RLAFSTDS+V+ P+ FPGG IG
Sbjct: 53  MSGELVEHLFLPAFGSAAEAGLADS-----AVVEIGGARLAFSTDSFVVKPMVFPGGTIG 107

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
            LA+ GT ND+A++GA+P  LS  FILEEG  ++ L  V  ++   A AAG+ +VTGDTK
Sbjct: 108 DLAVNGTVNDLAMAGAVPAVLSTAFILEEGTALDHLARVAQAVGTAALAAGVKLVTGDTK 167

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
           VV  G  D ++INT G+G +   +    Q    GDV++VSG LG HG  +L+ RE L   
Sbjct: 168 VVDSGHGDGVYINTTGIGLVDPRVDIRPQRAAPGDVVIVSGDLGVHGIAVLSCREGLEFA 227

Query: 194 GELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVK 252
             + SD A L  L+  + +    +  LRD TRGG+ A ++E A A G G+ +++ ALP+ 
Sbjct: 228 TSVASDAAPLHGLVAAMVETGADIHTLRDPTRGGLAATLNEIARAAGVGVSIADTALPIP 287

Query: 253 PAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG- 311
             VR  C +LGLD L  ANEGKLV  V    A++VLAA+H+HPLG  +A+IG  V     
Sbjct: 288 QEVRDACSMLGLDPLYVANEGKLVAFVPAADADEVLAAMHAHPLGAQSAVIGTCVPDHPG 347

Query: 312 -VRLAGLYGVKRTLDLPHAEPLPRIC 336
            V      G  R +DLP  E LPRIC
Sbjct: 348 MVVAKTALGGNRVVDLPIGEQLPRIC 373


>UniRef50_D1Y5N1 Hydrogenase expression/formation protein HypE n=1
           Tax=Pyramidobacter piscolens W5455 RepID=D1Y5N1_9BACT
          Length = 331

 Score =  261 bits (669), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 135/337 (40%), Positives = 176/337 (52%), Gaps = 10/337 (2%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
             I L  GSGG+    L+ S+     A                        LA +TD + 
Sbjct: 3   ELISLGEGSGGRLTADLVASVIKNFAACDGQKGG-------CEDCTFIEGNLAVTTDGFT 55

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           + P FFPGG++G LA+CG  ND+AV G  P++L+ G I+EEGLP   L  +V S A    
Sbjct: 56  VSPRFFPGGDMGHLAVCGATNDLAVRGVRPQWLTLGMIIEEGLPRAELLRLVRSAARQCE 115

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
           A G  +  GDTKVV RGA + +F N   +G        G   L  GD L++S   G HGA
Sbjct: 116 ALGATLAAGDTKVVPRGACEGVFFNVTALGRAVTPRPLGMNRLQPGDALILSTPPGRHGA 175

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            I  LR  L   G L SDCA L PL+  L  + G++ +RD TRGG+  V+ E+A A G G
Sbjct: 176 VIAALRYGLDRGG-LESDCAALWPLLGPLLPLDGLRCMRDCTRGGLGTVLCEWAEATGLG 234

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           +E+ E  L + P+V  +C++LG D L  A+EG  +IA      E  LA L  HPLG+DAA
Sbjct: 235 MEIEEERLALHPSVAAICDILGFDPLYLASEGCALIACAPAETEIALARLRRHPLGRDAA 294

Query: 302 LIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           LIG V       V L    G  R +D+P  E LPRIC
Sbjct: 295 LIGAVTAEHAGLVGLKTRLGGSRIVDMPVGEILPRIC 331


>UniRef50_C1TK23 Hydrogenase expression/formation protein HypE n=1
           Tax=Dethiosulfovibrio peptidovorans DSM 11002
           RepID=C1TK23_9BACT
          Length = 328

 Score =  261 bits (667), Expect = 4e-68,   Method: Composition-based stats.
 Identities = 132/338 (39%), Positives = 185/338 (54%), Gaps = 12/338 (3%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M  + L  GSGG+   +LI   F   F +  +         D   +  E    A + D +
Sbjct: 1   MGKLNLGQGSGGRLTSELIGK-FKAQFDDVNVQRD----LEDCTMISPE---WAVTIDGF 52

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + P+ FPGGNIGKLAICG  ND+AV G  P++++   I EEGL  E L     S A   
Sbjct: 53  TVSPMDFPGGNIGKLAICGGTNDLAVRGIEPKFVTLSVIAEEGLDEEELLRYGRSAASVC 112

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
               + +  GDTKVV +G VD LF+  A MG  P     G   +  GD L V+ ++G HG
Sbjct: 113 HGLEVKLAAGDTKVVPKGTVDGLFLTVASMGQ-PLGKPLGMDHIKPGDRLAVTTSIGRHG 171

Query: 181 ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
           ATI ++R  L ++G L SDCA L PL++ L  +PGV+A+RD TRGG+   + E+A   G 
Sbjct: 172 ATIGSIRFDLNVEG-LSSDCAPLWPLVKPLAVLPGVRAMRDCTRGGLGTTLCEWAEGTGL 230

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           GIE+ E+++P+   V  VC++LG D L+ A EG  +IA   +  ++++  L +HP G  A
Sbjct: 231 GIEIDESSIPIDEEVSSVCDILGFDPLHLACEGCALIAYSPDDEDRIIEILRAHPSGIQA 290

Query: 301 ALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
             IG VVE     V +    G  R +D+P  E LPRIC
Sbjct: 291 TSIGTVVEGHPSMVGMRTKAGGMRVVDMPVGELLPRIC 328


>UniRef50_D0SP02 Thiamine-monophosphate kinase n=1 Tax=Acinetobacter junii SH205
           RepID=D0SP02_ACIJU
          Length = 305

 Score =  255 bits (652), Expect = 2e-66,   Method: Composition-based stats.
 Identities = 61/305 (20%), Positives = 106/305 (34%), Gaps = 27/305 (8%)

Query: 17  QLINSLFMEA-FANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNI 72
            +I+  F  A   +  L   +D A L          +L   TD+ V    F        +
Sbjct: 5   SIIDRYFKRASHQDVSLGIGDDSAIL----TPLTSQQLVICTDTLVAGRHFPLDTSAHAV 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  ++    +D+A  GA P  +     L   +    L      + E      +A++ GDT
Sbjct: 61  GWKSVAVNLSDIAAMGAQPHSILLALSLP-SVDETWLAEFSRGLFECCDQFNVALIGGDT 119

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                    +L I    +G I             GD + VSG +GD    + +L      
Sbjct: 120 TQSS-----QLTITVTALGWIEQGQAITRAGAQVGDYICVSGQVGDAAYGLHHLGH---- 170

Query: 193 DGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
              L       TP  Q  + + G   ++ D +  G+   +     A G G  L    LP+
Sbjct: 171 --TLQQRLDYPTPRCQLGQRLKGRATSMIDVSD-GLAQDLGHILKASGVGATLFLDRLPI 227

Query: 252 KPAVRGV-CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
             A++ +  +     AL   ++ +L   +     E+    L  H       +IGE+ ++ 
Sbjct: 228 DSALKALDQQQAWQYALAGGDDYELCFTISPQKFEE----LSRHQSDVPFTIIGEITQQT 283

Query: 311 GVRLA 315
           G+   
Sbjct: 284 GLLFK 288


>UniRef50_C7G8J7 Hydrogenase maturation factor n=4 Tax=Clostridiales
           RepID=C7G8J7_9FIRM
          Length = 331

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 72/335 (21%), Positives = 135/335 (40%), Gaps = 23/335 (6%)

Query: 12  GQAMQQLINS-LFMEAFANPWLAEQEDQARLDLAQLV-AEGDRLAFSTDSYVIDPLFFPG 69
           G+  + ++   +F +                D A +  AE + L  STD     P+    
Sbjct: 8   GKVPENVLKRSVFKQIHTKRPEVVLGAGVGEDCAAVKLAEDETLVMSTD-----PITGTA 62

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            +IG LAI  TAND+A +GA P  +    +L   +    L+ ++  +      AG+ ++ 
Sbjct: 63  QDIGTLAIQITANDLASAGAEPVGVLLTVLLPPEIEEPDLREMMQQVEAACAKAGVQVMG 122

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           G T++     V++  I+  G+G +             G  +LV+  +G  G +I+   ++
Sbjct: 123 GHTEIT--AVVNQPVISVCGVGKVKDGCLISTGGAKPGMDILVTKWIGIEGTSIIAKEKE 180

Query: 190 LG----LDGELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGC 240
                      + +   L   +  L +       GV A+ D T GG+   + E A A G 
Sbjct: 181 KDLLTRFSAPFIENAKKLDVYLSVLSEAAVAVRSGVSAMHDVTEGGIFGALWEMAEASGV 240

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G+E+    +PV+     +CE  G++     + G +++A        ++  L     G  A
Sbjct: 241 GLEIDLKKIPVRQETIEICEFFGINPYELISSGSMLMAAADGNL--LVNELKKA--GIPA 296

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
            +IG+        L      +R L+ P  + L ++
Sbjct: 297 TIIGKATAGNDRVLLNED-ERRFLEPPKTDELYKV 330


>UniRef50_C5CEU2 Hydrogenase expression/formation protein HypE n=1 Tax=Kosmotoga
           olearia TBF 19.5.1 RepID=C5CEU2_KOSOT
          Length = 326

 Score =  253 bits (648), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 113/338 (33%), Positives = 178/338 (52%), Gaps = 22/338 (6%)

Query: 4   IQLAHGSGGQAMQQL--INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV 61
           I L H SG +  + L  I  L      +        +  +D             +TDS+ 
Sbjct: 6   ITLHHNSGKKQFKLLKHIEKLLGSTLVSTENDSGFLEEVVDT-----------VTTDSFT 54

Query: 62  IDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETAR 121
           I P+FFPGG+IGKL++CG+ ND+ ++GA P+Y++   +LEEG     L  ++ S+ +   
Sbjct: 55  ISPVFFPGGDIGKLSVCGSINDLVMTGAKPKYITLSVVLEEGFEFSRLDKIIDSIRKELD 114

Query: 122 AAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGA 181
             G+ I+ GDTKV++ GA+DK+ INT  +G +        + +   D+++++G +G HGA
Sbjct: 115 ENGVKIIAGDTKVMEHGALDKIVINTTCLGEVLYEK-LCVKRIETNDLIIITGPIGLHGA 173

Query: 182 TILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            I+  R+   +D    SDC VLT L+  ++ +  V A+RD TRGG+  +++EF+ +    
Sbjct: 174 AIMAERKGFQID--FQSDCRVLTKLLAVIKGLR-VHAMRDPTRGGLAQILNEFSHSTKRN 230

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             + E  LP+   V+ V E+LG+D L  A EG  VI      A+ +L  L +   G D +
Sbjct: 231 FAIYEDKLPIPGGVKTVSEILGIDPLYLACEGTAVIICHPEDAQDLLERLKNA--GFDPS 288

Query: 302 LIGEV---VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            IG V   +ER  + L    G KR L +   E  PRIC
Sbjct: 289 TIGFVGGIIERPLLILKTRNGAKRVLPMLVEELTPRIC 326


>UniRef50_B1YBW5 Hydrogenase expression/formation protein HypE n=7 Tax=Archaea
           RepID=B1YBW5_THENV
          Length = 366

 Score =  251 bits (643), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 125/346 (36%), Positives = 180/346 (52%), Gaps = 17/346 (4%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFAN----PWLAEQEDQARLDLAQLVAEGDRLAFSTDS 59
           I+L+HGSGG    +++  LF+                D      A  +A+G  L  + D+
Sbjct: 25  IKLSHGSGGVETSEIVEKLFLRRLPEGLKKVAGGLGLDFPDDAAAIPMADGRYLVVTVDA 84

Query: 60  YVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
           Y ++P FFPGG+IG LA  G+ NDV + G  P  +    I EEGLP ETL  VV S    
Sbjct: 85  YTVNPPFFPGGDIGMLAASGSINDVLMLGGRPLAMLDSIIAEEGLPYETLDRVVKSFLSV 144

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
             A G+A++ GD KV+ +G +DK+ I T G+G               GD ++VS  +GDH
Sbjct: 145 LEAEGVALIGGDFKVMPKGQLDKIVITTVGIGVADR---IIVDKPRHGDKIVVSDFVGDH 201

Query: 180 GATILNLREQLGLDGE---LVSDCAVLTPLIQTLRDIPG--VKALRDATRGGVNAVVHEF 234
           GA IL L+       E   L SD   LT L+  L +  G  + A RD TRGG+  V++++
Sbjct: 202 GAVILMLQMGDVDKPEQLQLKSDVKPLTKLMVPLVEKYGEYIHAARDPTRGGLAMVLNDW 261

Query: 235 AAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSH 294
           A A G  I + E +LPV+P V     +LG+D L  A+EG  V+AV+   AE+V+  +   
Sbjct: 262 AKAGGGVIVVEEESLPVRPEVASYAGMLGIDPLYLASEGAAVLAVDPAVAEEVVKFMRGL 321

Query: 295 PLGKDAALIGEVVE----RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
              ++A ++GE  E    R  V L  + G  R L+ P  + +PRIC
Sbjct: 322 GF-QNARVVGEFREARQHRGYVLLKTVAGGLRILEPPRGDIVPRIC 366


>UniRef50_A9KBN8 Thiamine-monophosphate kinase n=5 Tax=Coxiella burnetii
           RepID=A9KBN8_COXBN
          Length = 320

 Score =  251 bits (643), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 65/308 (21%), Positives = 127/308 (41%), Gaps = 21/308 (6%)

Query: 18  LINSLF---MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGN 71
           +I + F    +   N  +   +D A ++    + +  ++  S D+ V    F    P  +
Sbjct: 8   IIENYFHRPKKPAKNVVVGIGDDAAVIE----IPKEQQVVISVDTLVEGVHFPINTPPRD 63

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  A+  + +D+A  GAIP  +     + +      LKA        A    ++++ GD
Sbjct: 64  LGHKALAVSLSDIASMGAIPHTVLLALTI-QKTNEIWLKAFAEGFFSLADRYQVSLIGGD 122

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
                      L I+    G IP N        T GD++ ++GT+GD G  +  L++   
Sbjct: 123 VTQGP------LCISITATGLIPKNEMICRNGATVGDLIYLTGTVGDAGLALALLKQNKK 176

Query: 192 LDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           +D  L++     TP I+    + G+ +       GV A + + A A   G ++    LP+
Sbjct: 177 IDPFLLTRLNCPTPRIEAGVALRGIASAAIDISDGVVADLEKMARASQVGAKIYVERLPL 236

Query: 252 KPAVRGVCEL--LGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
             +++  C L      AL   ++ +L   + +  +E +      H L  +   IGE+++ 
Sbjct: 237 SDSLKRYCPLKKAWEYALTSGDDYELCFTIPKERSEPLEEVF--HSLDCECRCIGEIIQG 294

Query: 310 KGVRLAGL 317
           + V +   
Sbjct: 295 ESVTVIDP 302


>UniRef50_D1A5C3 Hydrogenase expression/formation protein HypE n=2
           Tax=Actinomycetales RepID=D1A5C3_THECD
          Length = 437

 Score =  250 bits (638), Expect = 6e-65,   Method: Composition-based stats.
 Identities = 145/295 (49%), Positives = 190/295 (64%), Gaps = 3/295 (1%)

Query: 45  QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGL 104
            +   G RLAF+TDSYV+ PLFFPGG+IG LA+ GT ND+AV GA P YLS GFILEEG 
Sbjct: 143 AMATAGPRLAFTTDSYVVSPLFFPGGDIGDLAVNGTVNDLAVCGARPLYLSAGFILEEGF 202

Query: 105 PMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTL 164
            +  L+ ++ SMA  A+ AG+ IVTGDTKVV RG  D  +I TAG+G +   I   A T+
Sbjct: 203 EVADLQRIIASMAAAAQRAGVQIVTGDTKVVGRGKADGCYITTAGVGLLDRPITLDAATV 262

Query: 165 TAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDI-PGVKALRDAT 223
             GD +LVSG +G+HG TI+  R +L ++ +L SD A L  L + L +   GV+ LRDAT
Sbjct: 263 RPGDAVLVSGPIGEHGVTIMLARGELDIEADLTSDTAPLNGLTEALLNATAGVRVLRDAT 322

Query: 224 RGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNA 283
           RGGV  V++E A A    I + EAA+P++P V G CELLG+D L  A EG+ V  V+   
Sbjct: 323 RGGVATVLNEIAQASQTAIVVDEAAVPIRPVVAGACELLGIDPLYVACEGRFVAIVDGAH 382

Query: 284 AEQVLAALHSHPLGKDAALIGEVVERKG--VRLAGLYGVKRTLDLPHAEPLPRIC 336
           A++ L  L +HPLG+DAA+IG V +     V     +G  R +D    +PLPRIC
Sbjct: 383 ADKALTVLQTHPLGRDAAIIGHVHDDPPSLVLGRTAFGGTRVIDTLVGDPLPRIC 437



 Score = 52.1 bits (124), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 23/48 (47%), Positives = 29/48 (60%)

Query: 2  NNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAE 49
            I LAHG+GG+A Q L+ SLF+ AF NP L   +D A LDL    + 
Sbjct: 24 ERITLAHGAGGKATQSLVESLFVAAFRNPALERLDDGAVLDLPAAASG 71


>UniRef50_Q5ZXK3 Thiamine monophosphate kinase (AIR synthase) n=6 Tax=Legionella
           RepID=Q5ZXK3_LEGPH
          Length = 325

 Score =  248 bits (633), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 78/329 (23%), Positives = 121/329 (36%), Gaps = 33/329 (10%)

Query: 18  LINSLFME---AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGN 71
           LI+  F        +      +D A       V +G  L  STD+ V    F P     +
Sbjct: 13  LIDHYFKSIPCKRNDVLFGIGDDAA----CLQVPDGMHLLVSTDTLVSGIHFLPQWDPYD 68

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           I   A+    +D+A  GA P +++    L E L    L +    + ++     + ++ GD
Sbjct: 69  IACKAVMVNISDMAAMGAQPCWVTLALTLPE-LNQSWLDSFARGIKDSLGLYNVDLIGGD 127

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T          L I    MG  P           AGD ++VSG LG  G  +  L E   
Sbjct: 128 TTKGP------LSITLTIMGLTPQGQAIRRCGAQAGDAIMVSGELGAAGLAVKLLDEHKK 181

Query: 192 LDG----ELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
           ++     EL++      P +           +  D +  G+ A ++   AA G G  L E
Sbjct: 182 VNAKDKVELMNKLLHPKPRVDLCHLLRKYATSAIDISD-GLGADLNHICAASGVGANLFE 240

Query: 247 AALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
            A+P  P +   C    LD AL+  ++ +L   V     +     L    L      IG 
Sbjct: 241 EAIPRHPLLNQYCPEQALDLALSGGDDYELCFTVSIQQLDSFNRDLQKENLI--CFPIGV 298

Query: 306 VVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           + E+ G+R+          D P  E  PR
Sbjct: 299 IEEKPGLRIQSA-------DSPSKELQPR 320


>UniRef50_B0VPT8 Thiamin-monophosphate kinase n=18 Tax=Moraxellaceae
           RepID=B0VPT8_ACIBS
          Length = 305

 Score =  247 bits (632), Expect = 4e-64,   Method: Composition-based stats.
 Identities = 61/306 (19%), Positives = 107/306 (34%), Gaps = 27/306 (8%)

Query: 17  QLINSLFMEA-FANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNI 72
            +I+  F      +  L   +D A +          +L    D+ V    F        I
Sbjct: 5   SIIDQYFNRQSHPDVALGIGDDSALI----TPPPNQQLVICADTLVAGRHFPLETLSHAI 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  ++    +D+A  GA P  +     L + +  E L+     + +     G+A++ GDT
Sbjct: 61  GWKSVAVNLSDIAAMGAKPHSILLAISLPQ-VDHEWLEGFSQGIYDCCNQFGVALIGGDT 119

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I    MG I             GD + VSG +GD    + +L      
Sbjct: 120 TQGPH-----LTITVTAMGWIETGKAVLRSGAKVGDYVCVSGQIGDAAYGLQHLGH---- 170

Query: 193 DGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
              L       TP  +   ++ G   ++ D +  G+   +     A   G  L    LPV
Sbjct: 171 --SLQQRLDYPTPRCKLGEELKGLASSMIDVSD-GLAQDLGHILKASKVGARLILEKLPV 227

Query: 252 KPAVRGVCELLGL-DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
            P ++ + E      AL   ++ +L   +     E++L       L     +IG++VE+ 
Sbjct: 228 DPVLQQLEEQQRWQYALAGGDDYELCFTITPQNYEKLLQ----KQLDVKITMIGQIVEQT 283

Query: 311 GVRLAG 316
            +    
Sbjct: 284 KLTFEH 289


>UniRef50_C9RAP1 Thiamine-monophosphate kinase n=1 Tax=Ammonifex degensii KC4
           RepID=C9RAP1_AMMDK
          Length = 339

 Score =  246 bits (628), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 76/312 (24%), Positives = 118/312 (37%), Gaps = 24/312 (7%)

Query: 30  PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVA 85
           P   E       D A L        F+TD  V    F        ++G   +    +D+A
Sbjct: 20  PSAREVIQGVGDDAAVLAVGDKWFLFTTDVLVEKVHFRWDLASPADVGFKTLAVNVSDIA 79

Query: 86  VSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI 145
             G  P Y      L    P+E ++     + E A    + +V GD         D  F 
Sbjct: 80  AMGGRPTYALVTLGLPLDFPVEKVEEFYAGLKEAAEEYEVILVGGDITRS-----DIFFA 134

Query: 146 NTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE-----LVSDC 200
             A +G +        +    GD+L V+G LG   A ++ L  +  L  E     L    
Sbjct: 135 GVALLGEVEPGKAKFRKGARPGDILCVTGPLGGAAAGLVLLESKEELLPETMAHFLRRKY 194

Query: 201 AVLTPLIQTLRDIP---GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRG 257
                 ++  R +     V AL D +  G+    H  A A G  + L  AALP+ P  + 
Sbjct: 195 RRPDARLEAGRILGDFEEVHALIDISD-GLAGDAHHLARASGVEVNLYRAALPIYPPAQE 253

Query: 258 VCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           +   LG+D     L    + +L+  VE +A  +V  AL    +G +   +G V E +GV+
Sbjct: 254 LGRRLGIDPARWALFGGEDYELLFTVEPSAVGKVAKALE--GVGLNLFPLGFVEEGEGVK 311

Query: 314 LAGLYGVKRTLD 325
           L    G +  L+
Sbjct: 312 LVLPDGREEELE 323


>UniRef50_A3DKG6 Hydrogenase expression/formation protein HypE n=1
           Tax=Staphylothermus marinus F1 RepID=A3DKG6_STAMF
          Length = 346

 Score =  244 bits (624), Expect = 3e-63,   Method: Composition-based stats.
 Identities = 104/345 (30%), Positives = 171/345 (49%), Gaps = 17/345 (4%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFA---NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           I   HGSGG    ++I  L +          L         D + +      +  STD++
Sbjct: 7   ITTVHGSGGFETLEIIEKLIVHRVPENLRKVLDGVGLDVLDDGSSMRIGNTHIVISTDNF 66

Query: 61  VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            + PLFFPGG+IG LA+ G  ND+ + GA P     G I+EEG P + L  ++ SM +  
Sbjct: 67  TVKPLFFPGGDIGHLAVSGVLNDLVMMGARPIAFMDGIIVEEGFPRDDLDRILESMIKLL 126

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
           +   +A++ GD KV+ + ++D L I+  G+G     I      +  GD ++V+G + +HG
Sbjct: 127 KENNVALIGGDFKVMPKKSLDGLIISGTGIGLAEKPII---DKIKPGDKIIVTGPIAEHG 183

Query: 181 ATILNLREQLGLDGE-LVSDCAVLTPLIQTLRD--IPGVKALRDATRGGVNAVVHEFAAA 237
           ATIL  +  +    + L SD   L   +  + +     + A RD TRGG++ V++E+   
Sbjct: 184 ATILAAQLGMLEQAQGLRSDTRPLVKTVLPILEKYRDHIHAARDPTRGGLSIVLNEWVRG 243

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
               I ++ + +P++  VR   + LG+D L  A EG  +++V+   A++++  LH     
Sbjct: 244 TKYTIVINRSTIPIRDEVRQFLDALGIDPLGVAGEGLAILSVDNEVADEIVEELHRRGEP 303

Query: 298 KDAALIGEVV--ERK----GVRLAGLYGVKRTLDLPHAEPLPRIC 336
             A +IGEV+  E +     V      G K  +  P+A  LPRIC
Sbjct: 304 Y-ATIIGEVIVPEEEYLAGRVIAITEVGGKVVVQ-PNALNLPRIC 346


>UniRef50_A4XL04 AIR synthase related protein domain protein n=2 Tax=Clostridia
           RepID=A4XL04_CALS8
          Length = 325

 Score =  244 bits (623), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 58/332 (17%), Positives = 124/332 (37%), Gaps = 19/332 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+   +++     +                D A +  + D    + D     P+   G  
Sbjct: 4   GKIPIEILKEHVFDQKIERSDILLAPGIGEDSAAVDVKSDIAVITMD-----PITAAGSM 58

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
            G L++    ND+A +GA P  + C  ++      E    ++  + E  +   I ++ G 
Sbjct: 59  SGYLSVVVVCNDLAAAGAEPIGVLCTILMPPESSQEEFIQILRDIKEACKRFNIQLLGGH 118

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           ++V     V K  I + G G +  ++         GD ++++ TLG  G  IL   ++  
Sbjct: 119 SEVSPI--VTKPLIVSTGFGKVERDMLISTSKAKVGDKIIITKTLGIEGTFILYNEKKEK 176

Query: 192 LD--------GELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
           L          E+ +    L+ + + L       ++ D T GG+   ++E   A G G  
Sbjct: 177 LKTFLTPEEVSEIENYINKLSVVEEGLVARKYASSMHDITEGGLFGAIYEVCKASGKGAR 236

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + E  + +  +V+ +     L+     + G ++I  ++               G D  ++
Sbjct: 237 IYEEKIVLSSSVKKISSFYNLNPYKLISSGSMLITTDKEN----ELICELKEKGIDCYVV 292

Query: 304 GEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           GE++E   +      G    +D    + + ++
Sbjct: 293 GEIIEEPKIEFINSSGEITLIDELPIDEIYKV 324


>UniRef50_A1HSU1 Thiamine-monophosphate kinase n=1 Tax=Thermosinus carboxydivorans
           Nor1 RepID=A1HSU1_9FIRM
          Length = 346

 Score =  243 bits (621), Expect = 7e-63,   Method: Composition-based stats.
 Identities = 80/325 (24%), Positives = 127/325 (39%), Gaps = 27/325 (8%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRL-AFSTDSYVIDPLFF----PGGNI 72
           LI+ +  +A   P           D A L+    +L   + D  V    F         +
Sbjct: 26  LIDLIQTDAIQEP--GTVVVGIGDDAAVLLPTPRQLQLLTADMLVEGVHFDLGRTTAWQL 83

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  AI    +D+A  G +PR+      L   +P+E +  +   M E  R   + IV GDT
Sbjct: 84  GYKAIAVNLSDIAAMGGVPRHAVISLALPRQIPVEFVVNLYQGMKEICREFRVNIVGGDT 143

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR----E 188
                G    L IN A MG +             GD++ V+G LG   A +  L      
Sbjct: 144 VASPHG----LIINVAVMGEVEPTQLVRRSGAQVGDMVAVTGVLGSSAAGLDLLSLDNWA 199

Query: 189 QLGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
           +      LV+      P ++   L  + G  ++ D +  G+ +  HE A A   G+ +  
Sbjct: 200 EYDFAWPLVTAHLTPRPQVKAGQLLGLYGATSMDDISD-GLASEAHEIAKASKVGLRIEA 258

Query: 247 AALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
             +P+ P ++    +LG +     L    + +LV  + R      L AL +   G    +
Sbjct: 259 KLVPLAPELKQAAAMLGKEPLDYALYGGEDYQLVFTIGREK----LQALSAVDFGVPLTV 314

Query: 303 IGEVVE-RKGVRLAGLYGVKRTLDL 326
           IGEV E   GV+L    GV++ L  
Sbjct: 315 IGEVTEAADGVKLVMDDGVEQELAP 339


>UniRef50_Q57190 Thiamine-monophosphate kinase n=279 Tax=Gammaproteobacteria
           RepID=THIL_HAEIN
          Length = 328

 Score =  243 bits (620), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 63/308 (20%), Positives = 115/308 (37%), Gaps = 27/308 (8%)

Query: 17  QLINSLFMEAF---ANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GG 70
            LI   F +      +  L+  +D A       V E  +LA +TD+ V +  F P     
Sbjct: 7   DLIKRYFQQQILVDDSVQLSIGDDCAL----VSVPENYQLAITTDTMVENTHFLPTISPE 62

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++   A+    +D+A  GA P+++S    L   +    +     S+  T +   + ++ G
Sbjct: 63  DLAYKAVATNLSDLAAMGAQPKWVSLALTLP-NVDENWISTFSQSLLHTLKQYNVTLIGG 121

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I     G +  N          GD++ VS TLGD  A +  +    
Sbjct: 122 DTTKGN------LSITITAQGFVEKNKGICRHKAQIGDLIYVSSTLGDSAAGLTQILLGK 175

Query: 191 ----GLDGELVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELS 245
                 D  L       TP I+  + + G+     D +  G+ + +        C  E+ 
Sbjct: 176 SAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSD-GLISDLGHILERSQCSAEVE 234

Query: 246 EAALPVKPAVRGVCELLGLD--ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
             ALP+  ++    +    +  AL+   + +L   +     +++   L    L      I
Sbjct: 235 LTALPLSSSILNKYDRTQAEQFALSGGEDYELCFTIPPEYKDELELRLKK--LNVPCTCI 292

Query: 304 GEVVERKG 311
           G++ E+ G
Sbjct: 293 GKINEKCG 300


>UniRef50_B5FBG0 Thiamine-monophosphate kinase n=7 Tax=Vibrionaceae
           RepID=B5FBG0_VIBFM
          Length = 332

 Score =  243 bits (620), Expect = 9e-63,   Method: Composition-based stats.
 Identities = 64/307 (20%), Positives = 116/307 (37%), Gaps = 26/307 (8%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLA-QLVAEGDRLAFSTDSYVIDPLFFPGGN---IG 73
           LI+  F++   N    + +     D A   V EG ++A +TD+      F    +   +G
Sbjct: 7   LIDRFFVQ--ENVSRDDVDLGIGDDCALVTVPEGYQVAITTDTLAAGTHFLADADPVSVG 64

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A+    +D+A  GA P ++S    L +    + L+       + A+   + ++ GDT 
Sbjct: 65  HKALASNLSDLAAMGAKPTWVSLALTLPQS-DEKWLEGFCRGFFDLAKQYQVELIGGDTT 123

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE----- 188
                    L I     G IP            GD + V+G LGD  A +  +       
Sbjct: 124 KGP------LSITITVQGIIPKGSALTRSAAQIGDDIYVTGNLGDSAAGLEVILNSHKNV 177

Query: 189 QLGLDGELVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           +  L+ EL       TP ++  +DI  +  A  D +  GV + +            ++  
Sbjct: 178 KGELEKELEKRHYYSTPQVELAQDIRHLCHAALDISD-GVISDLGHILKQSNVSAVINVN 236

Query: 248 ALPVKPAV----RGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
            LP+   +    R   E     AL    E +L     +   + +     +  L K  ++I
Sbjct: 237 NLPISSELVTYYRQDKEKCQKLALTSGEEYELCFTASKKNRKAIKQI--ATILNKKISII 294

Query: 304 GEVVERK 310
           GE++++ 
Sbjct: 295 GEIIDKP 301


>UniRef50_A6W2L4 Thiamine-monophosphate kinase n=2 Tax=Marinomonas
           RepID=A6W2L4_MARMS
          Length = 316

 Score =  242 bits (619), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 73/316 (23%), Positives = 123/316 (38%), Gaps = 23/316 (7%)

Query: 17  QLINSLFMEAFANPWLAEQED--QARLDLAQL-VAEGDRLAFSTDSYVIDPLF---FPGG 70
           +LI ++F  +         +       D AQ+ V +G  L FS D+ V    F       
Sbjct: 5   ELIQNIFQASVMASTQGRGDLLLGIGDDCAQVQVPQGQSLVFSMDTLVEGRHFPFDADPV 64

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IG  A+    +D+A  GA P + + G  + E    + L  +   MAE A   G+A+V G
Sbjct: 65  DIGYRAVASCVSDLAAMGAKPAFFTLGLTIPES-DPQWLAGLAQGMAELAEPIGLALVGG 123

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I     G +  ++         GD + V+G LGD  A +  +  +L
Sbjct: 124 DTTKGP------LTITLQVHGYVEPDMAVKRSGAKLGDDIYVTGVLGDAAAAVPIVTGEL 177

Query: 191 GLDGE-----LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
            +  E               LI  +     V A+ D +  G+   +     A G G  ++
Sbjct: 178 QVSSERFDYFYDRYWRPQPRLIVGMALKRVVHAMMDISD-GLAQDIQHILKASGVGANIN 236

Query: 246 EAALPVKPA-VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
            + +P+    +R   E     AL   ++ +L     ++ A ++  AL +  L      +G
Sbjct: 237 ASRMPISAELLRWQPESAVALALTGGDDYELCFTAPKDQAAEI--ALITQTLSLPCTKVG 294

Query: 305 EVVERKGVRLAGLYGV 320
           E+V   G  + G  G 
Sbjct: 295 EIVAE-GFVIQGYDGE 309


>UniRef50_D0KYD5 Thiamine-monophosphate kinase n=1 Tax=Halothiobacillus neapolitanus
           c2 RepID=D0KYD5_HALNC
          Length = 323

 Score =  241 bits (616), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 71/319 (22%), Positives = 116/319 (36%), Gaps = 35/319 (10%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLF---FPGGNI 72
           +LI   F    A+  +         D A L V EG+ L  STD  V    F       ++
Sbjct: 5   ELIARYFSRPCADASVVLG---VGDDCAALRVPEGEHLLVSTDLLVEGRHFPESTAAFDV 61

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P  ++ G  L   +  + L+A        A   GI +V GDT
Sbjct: 62  GYKAMAVNLSDLAAMGARPLGVTLGLALP-SIEPDWLEAFAKGFYTLAEQHGICLVGGDT 120

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L +    MG+ P +         +GD++ V+GTLGD G  + +++    +
Sbjct: 121 VKSPV-----LSLAVTIMGSAPPDRMLTRSGAQSGDLIAVTGTLGDAGLGLRSIQRPESM 175

Query: 193 DGELVS--------DCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIE 243
              L               TP  +  R +  V  A  D +  G+   +     A   G  
Sbjct: 176 PPSLNPEDIDFLQMRLNRPTPRGEEGRRLAEVAHAAIDISD-GLLQDLGHILRASHVGAV 234

Query: 244 LSEAALPVKPAVRGVCEL---LGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           +    LP+ PA R             L   ++ +L+  +  +             L   A
Sbjct: 235 VEADRLPISPAARAWLAADPTQHNLPLTAGDDYELLFTIAPDQW---------AMLDVPA 285

Query: 301 ALIGEVVERKGVRLAGLYG 319
            +IG + + K +R+    G
Sbjct: 286 TVIGRITQDKRLRVLDAQG 304


>UniRef50_B8D3R7 Hydrogenase expression/formation protein HypE n=1
           Tax=Desulfurococcus kamchatkensis 1221n
           RepID=B8D3R7_DESK1
          Length = 349

 Score =  241 bits (616), Expect = 2e-62,   Method: Composition-based stats.
 Identities = 105/347 (30%), Positives = 168/347 (48%), Gaps = 17/347 (4%)

Query: 2   NNIQLAHGSGGQAMQQLINSLFMEAFANPW---LAEQEDQARLDLAQLVAEGDRLAFSTD 58
             I   HG+GG     +I  L                      D + +      + F++D
Sbjct: 8   KIITTLHGAGGIESWNIIEKLIRGRVPRDLWSTPGGAGLDVLDDGSYIRIGESYIVFASD 67

Query: 59  SYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAE 118
           +Y + PLFFPGGNIG+L   G  ND+ + GA P       ++EEG  +  L+ +V SM +
Sbjct: 68  AYTVKPLFFPGGNIGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELEDIVDSMVK 127

Query: 119 TARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGD 178
           T     +A++ GD KV+ RG+VD + I+   +G           ++  GD ++V+  + +
Sbjct: 128 TLVENNVALIGGDFKVMPRGSVDGVVISGFAIGVSGKPPVV--DSIKPGDKIIVTNYIAE 185

Query: 179 HGATILNLREQ-LGLDGELVSDCAVLTPLIQTLRD--IPGVKALRDATRGGVNAVVHEFA 235
           HG+TIL  +   L     L SD   L   +  + +     + A RD TRGG+ A+++E++
Sbjct: 186 HGSTILAAQLDMLNDAPGLKSDVKPLVKTVLPVIEEYRDYINAARDPTRGGLAAILNEWS 245

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
            + G  I + +  +PV+  V    E+LG+D L  A+EG  V++V    A++V+ AL  + 
Sbjct: 246 RSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEALRRN- 304

Query: 296 LGKDAALIGEVVE------RKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
            G++  +IGEVVE      R  V      G    +  P A  LPRIC
Sbjct: 305 -GENPYIIGEVVEPRSRELRGRVVALTEVGGLTII-PPQAYNLPRIC 349


>UniRef50_B7R791 AIR synthase related protein, C-terminal domain n=2
           Tax=Thermoanaerobacteraceae RepID=B7R791_9THEO
          Length = 348

 Score =  240 bits (612), Expect = 7e-62,   Method: Composition-based stats.
 Identities = 74/332 (22%), Positives = 136/332 (40%), Gaps = 21/332 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+   +++                      + + ++  G+ +A        DP+      
Sbjct: 21  GKIPVEVMKRSIFPYLGTKRKEVLVHSQLGEDSSIIDFGEYVAV----LSTDPITAADKL 76

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
            G L++  + ND+A  GA P  +    +L EG   + LK ++  + + ++  GI ++ G 
Sbjct: 77  SGFLSVIISCNDLAACGAEPIGILTTILLPEGTEEQMLKNIMQEIDKASKMIGIEVLGGH 136

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ-- 189
           T+V    AV+K  I+T  +G      +  ++    GD ++V+  LG  G  IL    +  
Sbjct: 137 TEVT--QAVNKPVISTTAIGIARKGKYITSKGAKIGDDVIVTKALGLEGTAILATDYEDL 194

Query: 190 --LGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACGCGI 242
                  + V         I  + +       G  A+ D T GGV    +E + A G GI
Sbjct: 195 LIKHFGKDFVLKAQSFINEISVIEEGLIASQNGANAMHDITEGGVLGATYEISEASGLGI 254

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+ E  LP +   + +C+  GL+ L   + G ++I        +++ AL     G  A +
Sbjct: 255 EIYEEKLPFRRETKEICKFFGLNPLKLISSGSMLITA--EDGNRIVKALSEK--GIQATI 310

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           IG++V+  G  L    G +  L  P  + + R
Sbjct: 311 IGKIVKE-GRYLITSSGKEEIL-PPEKDEIYR 340


>UniRef50_A8MLK1 AIR synthase related protein domain protein n=3 Tax=Clostridiaceae
           RepID=A8MLK1_ALKOO
          Length = 330

 Score =  239 bits (611), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 67/333 (20%), Positives = 133/333 (39%), Gaps = 20/333 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQE-DQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+   +++  +      N             D A +         STD     P+     
Sbjct: 4   GKVPTEVLKEVIFSNLKNRRPEVLVRPNIGEDCAVVDFGDYVCVMSTD-----PITGAAK 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IG LA+  + ND+A SG  P  +    +       E L  V++   + A +  + I+ G
Sbjct: 59  DIGSLAVHISCNDIASSGVEPLGIMLTIMAPPHTTKEDLSLVMSEANKAAASVNVEIIGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN----L 186
            T++    AV+++ I+   +G         ++     D + ++   G  G  I+      
Sbjct: 119 HTEITD--AVNRMIISATAIGRQLKEKLVLSEGAKIDDAVFMTKYTGLEGTAIIARDLEE 176

Query: 187 REQLGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACGCG 241
           + +  +    +         I  +++       GV ++ D T GG+   + E   A G G
Sbjct: 177 KLKEKISDATIQTAQEFLKDISVVKEGITAGEVGVHSMHDVTEGGIFGALWELGEASGIG 236

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           IE+ E  +P++P    +C  L +D +   + G +V+ + ++  E ++ A     L     
Sbjct: 237 IEIYEDQIPMRPETLEICHYLSIDPMRLISSGVMVMTIAQDKKEALMEAFKRENLI--LT 294

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
            IG +VE+  + ++   G+ R LD P  + L +
Sbjct: 295 EIGRMVEKDRIIISAAKGI-RALDPPDVDELYK 326


>UniRef50_Q3II30 Thiamin-monophosphate kinase n=3 Tax=Alteromonadales
           RepID=Q3II30_PSEHT
          Length = 326

 Score =  239 bits (611), Expect = 1e-61,   Method: Composition-based stats.
 Identities = 64/308 (20%), Positives = 118/308 (38%), Gaps = 27/308 (8%)

Query: 17  QLINSLFMEAF---ANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GG 70
           +LIN  F        +  L   +D A       V +  +LA +TD+ V    FF      
Sbjct: 7   ELINRYFKGRGITRRDVNLGIGDDCAL----VTVPQNCQLAITTDTLVAGVHFFDDIEPR 62

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G  A+    +D+A  GA P ++S    L   +  + ++ +   M E A    + I+ G
Sbjct: 63  ALGHRALAVNLSDLAAMGAEPTWVSIALTLP-SIDQQWIEELTDGMHEIAEYFNVQIIGG 121

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I     G +P            GD + V+G LGD G  I + ++ L
Sbjct: 122 DTTQGP------LSITICAKGTVPEGTALCRNGAKVGDWIFVTGPLGDAGLAIESRKQGL 175

Query: 191 GLDGE----LVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELS 245
            ++ E    +       TP +   + + G   +  D +  G+ A +            ++
Sbjct: 176 TIEPEHLKHIKKRLNFPTPRVAAGQVLRGLASSAIDISD-GLLADLGHILNMSQVSATVN 234

Query: 246 EAALPVKPAVRGVCELLGLDA--LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
             ++P   A++   +        LN+ ++ +L+  V  +    +   L     G +A  I
Sbjct: 235 IESIPTSDAMKASLDFEQQLPFILNYGDDYELLYTVPDSNKSMLDVKLR--QYGVEAICI 292

Query: 304 GEVVERKG 311
           G++   +G
Sbjct: 293 GQIKSGEG 300


>UniRef50_A8ZNV6 Hydrogenase expression/formation protein HypE n=2 Tax=Bacteria
           RepID=A8ZNV6_ACAM1
          Length = 339

 Score =  238 bits (609), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 66/334 (19%), Positives = 122/334 (36%), Gaps = 22/334 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+    L+  L  +   +            D A +          +D     P+ F   +
Sbjct: 9   GKLPSHLLAHLLSQTPIHDPQVLLGPGIGHDCAVVDGGAKLWVIKSD-----PITFVTDD 63

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETL-KAVVTSMAETARAAGIAIVTG 130
           IG   +   AND+A +GA PR+L    +L E     TL + +   +    +   ++++ G
Sbjct: 64  IGWYVVQINANDIATTGATPRWLMATILLPEQRTTATLAERIHQQIYTACQEINVSLIGG 123

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T++     +D+  +    +G +  +     +    GD +L++ ++      IL      
Sbjct: 124 HTEIT--YGIDRPIVVGTLIGEVARDSLITPRGAKPGDRILLTKSVPIEATAILAREYSE 181

Query: 191 GLDGELVSDC------AVLTPLIQTLRDI------PGVKALRDATRGGVNAVVHEFAAAC 238
            +   L SD        +  P I  LRD         V A+ D T GG+ A + E A A 
Sbjct: 182 QISQALTSDELTQARGYLYKPGISVLRDAQLANQAGQVSAMHDPTEGGLLAALWELAQAS 241

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
            C + +    +P+      +C +  +D L     G L++   +  A  +   L  +  G 
Sbjct: 242 NCQLVIDLEKVPISDLSAHICRVFKIDPLAAIASGALLLTAPQRDAPSICRTL--NTSGI 299

Query: 299 DAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
               IG+V        +     K  L  P  + +
Sbjct: 300 PCCEIGDVQSGNATVWSRTALEKERLPCPSRDEI 333


>UniRef50_A5EUI7 Hydrogenase expression/formation protein n=4 Tax=Proteobacteria
           RepID=A5EUI7_BRASB
          Length = 346

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 148/335 (44%), Positives = 199/335 (59%), Gaps = 4/335 (1%)

Query: 3   NIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVI 62
            + LAHG+GG+ M+QLI  LF+    N  L    D A L     +  G     +TD + +
Sbjct: 15  RVSLAHGNGGRRMRQLIEELFVRHLGNALLDTDADAAALP---PLPTGATPMITTDGFTV 71

Query: 63  DPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           DPL FPGGNIG LA+ GT ND+AVSGA P YL+    LEEGL +  L  +  SMA  A  
Sbjct: 72  DPLEFPGGNIGSLAVHGTVNDLAVSGAEPLYLTLNCFLEEGLDLGLLDRLTASMAAAATE 131

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
           AG+ +V GDTKVV+RG    +++ T+G+G   A +  G   + AGD +LVSG +GDHG  
Sbjct: 132 AGVKVVAGDTKVVRRGEGGGVYLATSGVGLRRAGLDLGLGRIAAGDHILVSGPVGDHGTA 191

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
           +L  R Q GL G+LVSD A + P+ + L D+PG++ +RD TRGG+  V HE     G GI
Sbjct: 192 VLLARGQFGLRGDLVSDSASVLPVTRALVDVPGLRFMRDPTRGGLATVAHEIVRHTGMGI 251

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            LSE A+P++  VR VCE+LG + L  A+EG++V  V+  +A   LAA+       DA  
Sbjct: 252 RLSEPAIPIRDQVRAVCEMLGYNPLYLASEGRVVAVVDPASAPAALAAMRGPGQSPDAVE 311

Query: 303 IGEV-VERKGVRLAGLYGVKRTLDLPHAEPLPRIC 336
           IG V  E   V L    G +R ++   A+PLPRIC
Sbjct: 312 IGTVGCEEPYVVLETEIGGERLIEELEADPLPRIC 346


>UniRef50_A3Z0T5 Hydrogenase expression/formation protein; HypE n=1
           Tax=Synechococcus sp. WH 5701 RepID=A3Z0T5_9SYNE
          Length = 343

 Score =  238 bits (608), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 144/323 (44%), Positives = 186/323 (57%), Gaps = 10/323 (3%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGK 74
            Q+L+  + + A          D   LD A L  E   LAFSTD +V+ PL FPGG+IG 
Sbjct: 30  SQRLLEQVILPALGAT------DGVLLDAASLTTEAGELAFSTDGHVVRPLEFPGGDIGA 83

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
           LA+ GT ND+A+ GA P  LS G ILEEGLP+  L  V++S A  A   G+++VTGDTKV
Sbjct: 84  LAVFGTVNDLAMLGATPLALSLGLILEEGLPLSILSRVLSSAAAAAARCGVSVVTGDTKV 143

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
           V+RG  D LF+ TAG+G IPA +  G   + +GD +LVSG LG HG  IL  RE+LG   
Sbjct: 144 VERGKADGLFMTTAGIGRIPAGVSIGPSAIRSGDAILVSGDLGRHGLAILAAREELGFST 203

Query: 195 ELVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
            L SD A L   +Q L      + ALRD TRGG+ A +HE     G G  + EA +PV  
Sbjct: 204 SLESDLAPLHGSVQALLAAGLELHALRDLTRGGLAAALHELCRDAGLGGLVHEAVVPVHA 263

Query: 254 AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           AV   CELLGLD L  A+EG+ V+ +  + A+  L  L        AA+IG +   + + 
Sbjct: 264 AVATACELLGLDPLTMASEGRFVMMLPASQAQDALKLLRHEQS--SAAVIGRI-GGEALL 320

Query: 314 LAGLYGVKRTLDLPHAEPLPRIC 336
           L    GV+R L+L   E LPRIC
Sbjct: 321 LETSLGVRRPLELGRGELLPRIC 343


>UniRef50_Q15W96 Thiamine-monophosphate kinase n=2 Tax=Alteromonadales
           RepID=Q15W96_PSEA6
          Length = 336

 Score =  237 bits (606), Expect = 3e-61,   Method: Composition-based stats.
 Identities = 67/303 (22%), Positives = 108/303 (35%), Gaps = 26/303 (8%)

Query: 17  QLINSLFME---AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GG 70
            LI++ F +      +  L   +D A       +  G  LA +TD+ V    F P     
Sbjct: 5   SLIDTYFRDVSFQRKDVLLGIGDDCAI----TQIPAGQALATTTDTLVSGVHFLPDADPK 60

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            I + AI    +D+A  GA P +LS    L   +  + LKA      E      + ++ G
Sbjct: 61  AIAQKAIAVNLSDLAAMGAEPAWLSLSLSLP-NVDEQWLKAFSEGFRELTEYYSVQLIGG 119

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I     G + A+          GD + V+G+LGD G  +  L  + 
Sbjct: 120 DTVQGP------LAITITAQGFVAADQALKRSGAKPGDFVYVTGSLGDAGLGLDILLNRA 173

Query: 191 GL-----DGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
            +        L+      TP +     +  V +       G+ A +     A  CG  L 
Sbjct: 174 EVKSTEHSEYLLKRLHYPTPRVFAGTSLRRVASACIDISDGLLADIKHILKASQCGACLQ 233

Query: 246 EAALPVKPAVRGVCELLGL--DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
              LP+  A+    +       AL+  ++ +L+  V       V   L        A  I
Sbjct: 234 LDKLPLSKAMLESADRDAAFHYALSSGDDYELLFTVSEEQKNNVERVL--ACSNVPATCI 291

Query: 304 GEV 306
           G++
Sbjct: 292 GQI 294


>UniRef50_A8PLC8 Thiamine-monophosphate kinase n=2 Tax=Gammaproteobacteria
           RepID=A8PLC8_9COXI
          Length = 323

 Score =  237 bits (606), Expect = 4e-61,   Method: Composition-based stats.
 Identities = 63/317 (19%), Positives = 110/317 (34%), Gaps = 26/317 (8%)

Query: 17  QLINSLF---MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GG 70
           +LI   F   M+   +  L   +D A L+    V    +L  STD++V    F       
Sbjct: 7   ELIQRFFNQPMKCRNDVTLGIGDDGAVLN----VPFNQQLVVSTDTFVAGRHFPEETLPE 62

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           +IG  A+    +D+A   A P ++     L   +    LK          +   + +V G
Sbjct: 63  DIGYKALAVNLSDLAAMAAEPAWILLALTLP-HVDETWLKKFNQGFFSLIQQFQLQLVGG 121

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR--- 187
           D           L I    +G +P            GD + V+GTLGD G  +  +    
Sbjct: 122 DLTRGP------LSITVHALGFVPQGKALRRLGAHIGDKIYVTGTLGDAGLALALMNTPS 175

Query: 188 -EQLGLDG--ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
              L       +        P ++    +  + +       G+ A +H   +A   G  +
Sbjct: 176 CCGLTQSQIFSVKQRLHRPHPRVEVGIALRDIASCAIDISDGLMADLHHLLSANQVGAIV 235

Query: 245 SEAALPVKPAVRGVC-ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
               LP+  ++RG+  E     AL+  ++ +L   V  +    +   L    +      I
Sbjct: 236 QLEKLPLSDSLRGLSPEKAWSLALSSGDDYELCFTVPESKERDLQQQL--ATINTPYQCI 293

Query: 304 GEVVERKGVRLAGLYGV 320
           G +    G+ L    G 
Sbjct: 294 GHIKADSGLILLDKKGA 310


>UniRef50_A1S0T2 AIR synthase related protein domain protein n=2 Tax=Archaea
           RepID=A1S0T2_THEPD
          Length = 335

 Score =  236 bits (604), Expect = 7e-61,   Method: Composition-based stats.
 Identities = 89/334 (26%), Positives = 130/334 (38%), Gaps = 19/334 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+     +  L                   D A +      L    D     P+     N
Sbjct: 7   GKLTYGELEELLSRLRRQDASVLLGPAIGEDAALIDLGDKVLVVHAD-----PITGAVSN 61

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           IG L++  +ANDVA  G  PR+L    +L EG   + L  +   + + A   G  IV G 
Sbjct: 62  IGWLSVHVSANDVATRGVQPRWLVTVVLLPEGAGQDVLWDIAGQLRKAADEIGATIVGGH 121

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T+      +D+  + T  MG               GD L+++   G  G  IL       
Sbjct: 122 TEFTP--GLDRPILVTTAMGVGGKGEVLATSRARPGDALILTKGAGIEGTAILATELYDE 179

Query: 192 L----DGELVSDCAVLTPLIQTLRD------IPGVKALRDATRGGVNAVVHEFAAACGCG 241
           L    D E++         +  ++D        GV A+ D T GGV   + E A A   G
Sbjct: 180 LSRKVDREVLERAKSFIYEVSVVKDALTAVRAGGVHAMHDPTEGGVLGGLQEMAIAANAG 239

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           + + E  +PV+   + VC  LG+D L   + G L+IAVE + A  V+ AL     G  AA
Sbjct: 240 LVVEEEKIPVREETKAVCRALGVDPLRLISSGSLLIAVEGSRARDVVDALSRE--GIPAA 297

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           +IG + E     L    G    L+ P  + L RI
Sbjct: 298 VIGRLTEGSERILVKRGGEIVDLNEPVVDELWRI 331


>UniRef50_C0ZK37 Thiamin-monophosphate kinase n=1 Tax=Brevibacillus brevis NBRC
           100599 RepID=C0ZK37_BREBN
          Length = 338

 Score =  235 bits (601), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 60/312 (19%), Positives = 106/312 (33%), Gaps = 27/312 (8%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVA-EGDRLAFSTDSYVIDPLF----FPGGN 71
            LI      +               D A         +    D+ V    F        +
Sbjct: 7   SLIRQWTSRSAGQEGNG-LTVGIGDDAAVFSPAPEMEVVACCDAMVETVHFLKKTMNPSD 65

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           IG  A+    +DVA  G + RY      +      +  + +   + E  +A G+ ++ GD
Sbjct: 66  IGYKAVISNVSDVAAMGGVARYALVSIAVSPQWTPDECQQIYEGIYEACQAYGVRVIGGD 125

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T        D L ++   +G +             G ++ V+G +G   A +  L +   
Sbjct: 126 TVSAP----DALHLSVTVLGEVEKGRAIRRSQAKPGQLVFVTGHVGTSAAGLHLLLQGET 181

Query: 192 LD-------GELVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            +         L+         I   + L +     AL D +  G+ + + E A A G  
Sbjct: 182 AERGVSASWETLMDAHQRPVAQIKAGRLLLESGACSALNDVSD-GLASELWEIAEASGVS 240

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLG 297
           I +  A +P+   VR     +  D L +      + +LV  + ++  E V         G
Sbjct: 241 ILVDAATVPIHDEVREYARHVEKDPLEWAFYGGEDYQLVGTLAKSHYEAVSKQF--AVSG 298

Query: 298 KDAALIGEVVER 309
               +IGEVVE+
Sbjct: 299 VRFTVIGEVVEK 310


>UniRef50_C9L525 Hydrogenase maturation factor n=1 Tax=Blautia hansenii DSM 20583
           RepID=C9L525_RUMHA
          Length = 344

 Score =  235 bits (600), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 73/335 (21%), Positives = 136/335 (40%), Gaps = 23/335 (6%)

Query: 12  GQAMQQ-LINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFFPG 69
           G+  +  LI S+  +                D A +  E G+    S D     P+    
Sbjct: 20  GKLPEPVLIRSVLKQVGHRRNEVLVGPAVGQDCAVMELEEGEVFVLSCD-----PITGTT 74

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            +IG  ++  TAND+A SGA P  +    +L        LK ++  + +T +   + ++ 
Sbjct: 75  KDIGGHSVHITANDLAASGAEPVGIMLTMLLTPDTEEAQLKEIMQDVEKTCKELNMEVLG 134

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           G T+V     V +  I+  G+G +         ++  GD ++V+  +G  G +I    ++
Sbjct: 135 GHTEVTDV--VKQTLISLTGVGKMKKENVLTTASVKPGDDIVVTKWIGLEGTSIAAKEKE 192

Query: 190 ----LGLDGELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGC 240
                      V         +  + +       GV A+ D T GGV   + E  +  G 
Sbjct: 193 SLLLEHFAPPFVETAKKFDQYLSVIPEAKIAAEWGVSAMHDITEGGVFGALWEMGSGSGV 252

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G+++    +P++     VCE+LGL+     + G ++IA +      ++  L     G +A
Sbjct: 253 GLDIDLKEIPIRQETVEVCEVLGLNPYILMSSGSMMIAAKDGYG--LVRKLKQA--GIEA 308

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           A++G+  +     L       R LD P ++ L +I
Sbjct: 309 AVVGKATDGNDRILRNGEDT-RYLDKPQSDELYKI 342


>UniRef50_A0M637 Thiamine-monophosphate kinase n=43 Tax=Bacteroidetes
           RepID=A0M637_GRAFK
          Length = 351

 Score =  235 bits (599), Expect = 2e-60,   Method: Composition-based stats.
 Identities = 67/333 (20%), Positives = 118/333 (35%), Gaps = 40/333 (12%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIG 73
           LI+ L      +P L         D A L  +  +   STD  V    F     P  ++G
Sbjct: 20  LIDHLTKNF--SPKLESTIKAIGDDAAVLNFKNKQTLISTDLLVEGVHFDLAYMPLKHLG 77

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A+    +D+         ++  F      P+E L+ +   +   A+   + ++ GDT 
Sbjct: 78  YKAVMVNLSDIYAMNGTATQITVSFAASNRFPVEALEELYAGIQLAAKLYNVDVIGGDTT 137

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL- 192
               G    L I+   +G              A D+L++SG LG     +  L  +  + 
Sbjct: 138 SSTSG----LMISVTAIGIAEKEEITYRNGAKANDLLVLSGDLGAAYMGLQVLEREKQVF 193

Query: 193 --DGELVSDCAVLTPLIQT------------LRDIPGV--KALRDATRGGVNAVVHEFAA 236
             +     D    T LI+             L     V   ++ D +  G+++ V     
Sbjct: 194 KANPNSQPDLDQYTYLIERQLKPEARQDIPPLLKELEVQPTSMIDISD-GLSSEVIHLCK 252

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALH 292
               G  L E  +P+ PAV  VCE   +D    AL+   + +L+  + ++  +++     
Sbjct: 253 NSKLGANLFEEKIPLDPAVISVCEEFEIDSTMVALSGGEDYELLFTISQDDYDKI----- 307

Query: 293 SHPLGKDAALIGEVVERK-GVRLAGLYGVKRTL 324
                    +IG + E   G+ L      K  L
Sbjct: 308 --KGNPHLTVIGHMTEENEGMHLVTRANQKLPL 338


>UniRef50_B8I2N9 AIR synthase related protein domain protein n=6 Tax=Clostridium
           RepID=B8I2N9_CLOCE
          Length = 330

 Score =  233 bits (596), Expect = 6e-60,   Method: Composition-based stats.
 Identities = 74/336 (22%), Positives = 139/336 (41%), Gaps = 23/336 (6%)

Query: 12  GQAMQQLINSLFMEAFAN-PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+    ++N +                    D A +  +      STD     P+   G 
Sbjct: 4   GKLPNDILNKIVFGKINTFRKEVIMRPGIGEDCAAIEFDKYACVMSTD-----PITAAGK 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           N G+LA+  + ND+A SG  P  L    +   G     L+ ++  + ETA    + I+ G
Sbjct: 59  NAGRLAVHISCNDIASSGVEPLGLMVTILCPVGTTETELEHLMDQVCETAGQLNVEIIGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T+V    AV+K+ ++T  +G    +    +     GD ++++ + G  G  I+    + 
Sbjct: 119 HTEVTP--AVNKIILSTTCVGKSLKDKIISSSGAKPGDSVILTKSAGLEGTAIIAGDFEE 176

Query: 191 GLDGEL-VSDCAVLTPLIQT--------LRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            L   +  ++      LI          L    GV ++ D T GGV     E A A   G
Sbjct: 177 ELAEVMNKNELQYAKSLINAISVVPEGVLAGRFGVTSMHDITEGGVLGAAWEIAEASSTG 236

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           + + + ++PV+P  R +C+  G++ L   + G ++I       E ++  L  +     A+
Sbjct: 237 VTIKKDSIPVEPVTRHICDHFGINPLRLISSGCMIITC--KDGEGLVRLLGEN--NIKAS 292

Query: 302 LIGEVVERK--GVRLAGLYGVKRTLDLPHAEPLPRI 335
           +IG + + K   + ++   G    ++ P A+ L +I
Sbjct: 293 IIGTITQNKTGRLLISEKEGTSENIEAPGADELYKI 328


>UniRef50_A4SVD0 Thiamine-monophosphate kinase n=1 Tax=Polynucleobacter necessarius
           subsp. asymbioticus QLW-P1DMWA-1 RepID=A4SVD0_POLSQ
          Length = 339

 Score =  233 bits (595), Expect = 7e-60,   Method: Composition-based stats.
 Identities = 58/320 (18%), Positives = 110/320 (34%), Gaps = 25/320 (7%)

Query: 17  QLINSLFMEAFANPWLAEQED-QARLDLAQLV-AEGDRLAFSTDSYVIDPLFF---PGGN 71
            LI   F    +     E        D A +  A    +A +TD  V    FF       
Sbjct: 12  DLIERFFKTGTSATEQNENIPLGIGDDCALIKQATDSEIAITTDMLVEGRHFFAGADPEQ 71

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G+ A+    +D+A  GA P   +    + +   +  L+A    + ++A   G  ++ GD
Sbjct: 72  LGRKALAVNLSDLAAMGAEPLGFTLAIAMPKA-DIAWLEAFSKGLLDSANLYGCPLIGGD 130

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T          L ++   +G IP             D + VSG +GD    +  LR ++ 
Sbjct: 131 TTAGP------LTLSITALGNIPQGKAIRRSGAKIEDDVWVSGNVGDARLALAALRHEIP 184

Query: 192 LDGE----LVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSE 246
           L  E    +       TP I+    +  +  A  D +  G+   ++          ++  
Sbjct: 185 LSAEDLKQVEKRMHQPTPRIELGIGLRDIATAALDISD-GLLGDLNHVLKQSQVDAQIFL 243

Query: 247 AALPVKPAVRGVC-ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
             +P    ++    ++    A +  ++ ++      +  E +     S  L     LIG 
Sbjct: 244 NQIPKSETLKKQSTDIQNQFAASGGDDYEICFTAPNHQREAIKKL--SKSLDLPLTLIGR 301

Query: 306 VV----ERKGVRLAGLYGVK 321
           ++    +   V L    G  
Sbjct: 302 IIPIKNKNPQVHLINSDGAT 321


>UniRef50_Q65TX9 ThiL protein n=4 Tax=Pasteurellaceae RepID=Q65TX9_MANSM
          Length = 331

 Score =  233 bits (594), Expect = 8e-60,   Method: Composition-based stats.
 Identities = 66/335 (19%), Positives = 107/335 (31%), Gaps = 30/335 (8%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFP---GGNI 72
            LIN  F  +   P           D A   +    RLA +TD+ V +  F+P      +
Sbjct: 7   DLINRYFALSKQIPRQD-VILSIGDDCAITQLKADQRLAVTTDTMVENSHFYPTIPPRAL 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P ++S    L +      L      M E      + ++ GDT
Sbjct: 66  GYKAVATNLSDLAAMGATPTWVSLALTLPK-TDSHWLNEFSKGMFEILNRYDVTLIGGDT 124

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG- 191
                   +   +     G +  +          GD + VSGTLGD  A     R+    
Sbjct: 125 T-----KGEIPTVTITAQGLL-GDYALCRHQAKIGDWIYVSGTLGDALAGFYLNRDIYEG 178

Query: 192 -------LDGELVSDCAVLTPLIQ---TLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
                   +   +       P I+   TL       A  D +  G    +          
Sbjct: 179 KKSAVGFDEDFFIQRNLYPIPRIEFGKTLAKYRLANAALDISD-GFMGDLMHILERSQVS 237

Query: 242 IELSEAALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
             ++   LP+ P +      E   L AL    + +L   V      ++   L   PL   
Sbjct: 238 AVVNLEDLPLSPQLSAYYGREKAELMALQGGEDYELCFTVSDENKTKLDQYL--APLNVP 295

Query: 300 AALIGEVV--ERKGVRLAGLYGVKRTLDLPHAEPL 332
              +G++   E   V     Y  +  L +   +  
Sbjct: 296 YTCVGQICAAEDNPVIRLQRYKQEVNLSIHSFDHF 330


>UniRef50_A0L3Z7 Thiamine-monophosphate kinase n=1 Tax=Magnetococcus sp. MC-1
           RepID=A0L3Z7_MAGSM
          Length = 338

 Score =  232 bits (593), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 73/320 (22%), Positives = 115/320 (35%), Gaps = 33/320 (10%)

Query: 18  LINSLFME----AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGG 70
           +I  +F            L   +D A      +V     L  +TD+ V    F       
Sbjct: 14  VIQHIFAPIQSKQGEGVQLGIGDDAA----CLVVPRTQDLLATTDTMVEGIHFSSDADPY 69

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G+ A+    +D+A  G +PR+      +        L+     +   +    +A+V G
Sbjct: 70  LLGQKALAVNLSDIAAMGGLPRWYLLSMAVPNRTSQSWLEEFARGVKAASEMFHVALVGG 129

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT         K+ I    +G I  +          GD L +SGTLGD    + +L  +L
Sbjct: 130 DTVRSNA----KIVITVQMLGLIGQHRAVARSGAQVGDRLYLSGTLGDSAFGLAHLLGKL 185

Query: 191 -----GLDGELVSDCAVLTPLIQ---TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
                     L     +  P IQ    L+D     A  D +  G+ A +     A     
Sbjct: 186 PAMLADDVSYLSRRHHLPEPRIQLGMALQDAALAHACIDVSD-GLLADLQHICEASQVSA 244

Query: 243 ELSEAALPVKPAVRGVCELLG----LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
            +    LP   + + V    G      AL    + +L+ A+   AA+QV   +  H +G 
Sbjct: 245 VVDVEKLPFSESAQRVIAQYGRSALELALTGGEDYELLFAISPGAADQVEKIV--HQVGV 302

Query: 299 DAALIGEVV---ERKGVRLA 315
               IGEVV   ER GV + 
Sbjct: 303 SLVEIGEVVGVGERPGVVVR 322


>UniRef50_B0KA39 AIR synthase related protein domain protein n=10 Tax=Clostridia
           RepID=B0KA39_THEP3
          Length = 331

 Score =  232 bits (592), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 68/331 (20%), Positives = 133/331 (40%), Gaps = 21/331 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+   +++                      + + ++  G+ +A        DP+      
Sbjct: 4   GKVPVEILKRSVFPYLGVKRKEVLVHSQLGEDSSIIDFGEYVAV----LSTDPITAAEKL 59

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
            G L++  + ND+A  GA P  +    +L EG     L  ++  + + A+   I ++ G 
Sbjct: 60  SGFLSVIISCNDLASCGAKPIGILSTILLPEGSDESVLHNLMEEIDKAAKKLNIEVLGGH 119

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ-- 189
           T++     V+K  I+T  +G      +   +    GD ++V+  LG  G  IL    +  
Sbjct: 120 TEITT--TVNKPIISTTAIGMAKKGEYITTKGAKIGDDVIVTKALGLEGTAILATDYEDL 177

Query: 190 --LGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACGCGI 242
                D + +         I  + +       G  A+ D T GG+    +E A A G GI
Sbjct: 178 LLKRYDKDFILKAQSFINEISVIEEGLIAAQNGANAMHDITEGGILGAAYEIAEASGLGI 237

Query: 243 ELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           E+ E  LPV+P  + +C   G++ L   + G ++I       ++++ +L     G  A +
Sbjct: 238 EIYEEKLPVRPETKEICRFFGINPLKLISSGSMIITAS--DGDKIVKSLSEK--GIQATI 293

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
           IG++++  G  L    G +  +  P  + + 
Sbjct: 294 IGKIIKE-GKYLITSKGKEE-ITPPERDEIY 322


>UniRef50_B3PBC5 Thiamine-monophosphate kinase n=1 Tax=Cellvibrio japonicus Ueda107
           RepID=B3PBC5_CELJU
          Length = 326

 Score =  232 bits (592), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 72/308 (23%), Positives = 118/308 (38%), Gaps = 21/308 (6%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLF---FPGGNI 72
           QLI   F    A    A        D A L + EG +LA S D+ V    F        I
Sbjct: 11  QLIQQFFQREQAEQPAAGVVLGIGDDCALLQIPEGKQLAVSVDTLVSGVHFPEGAEPALI 70

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
            + A+    +D+A  GA P + +    L +    + L+     +   A+  GIA++ GDT
Sbjct: 71  AERALRTNLSDLAAMGAEPLWFTLALTLPQA-EEQWLREFSRGLFACAKRYGIALIGGDT 129

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L ++   MGA+             GD +LV+ ++GD  A + +L+ ++  
Sbjct: 130 TAGP------LSVSIQVMGAVTPGQALRRDGANLGDFILVTHSVGDGAAALASLQGRVSF 183

Query: 193 DGE----LVSDCAVLTPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
            G+    L        P +Q   R  P   A  D +  G+ A +     A   G  +   
Sbjct: 184 SGDDHAYLHERFYRPEPRLQASARIRPFASAALDISD-GLVADLQHICTASDLGAVIDVE 242

Query: 248 ALPVKPAVRGVCELLG--LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           ALP+  A+    +       AL+  ++ +L   V       +  A+        A++IGE
Sbjct: 243 ALPLSSALVAYPDRTQAYEWALSGGDDYELCFTVAPENMPDI--AMLIAQGQLQASVIGE 300

Query: 306 VVERKGVR 313
           +V    V 
Sbjct: 301 MVAGNRVI 308


>UniRef50_Q5FNA0 Thiamin-monophosphate kinase n=1 Tax=Gluconobacter oxydans
           RepID=Q5FNA0_GLUOX
          Length = 325

 Score =  231 bits (591), Expect = 2e-59,   Method: Composition-based stats.
 Identities = 66/310 (21%), Positives = 112/310 (36%), Gaps = 16/310 (5%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGKL 75
           I   F        L  ++D A +       EG+  A STD+ V +  F P      +G+ 
Sbjct: 18  IARHFRPLAGAESLDLRDDCALMRC----PEGEEFAISTDTMVENVHFLPDDPPETLGRK 73

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEG--LPMETLKAVVTSMAETARAAGIAIVTGDTK 133
            +    +D+A  GA P   +    +  G         A    +AE  +  G+ ++ GDT 
Sbjct: 74  LLRCNLSDLAAMGARPHAYTLNVTVTRGGRHDENWFAAFSRGLAEDQQRYGVHLIGGDTT 133

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
            +       L ++    G +  N      T   GD + V+GT+GD    +L L+  L   
Sbjct: 134 SISG----PLVLSATVFGLLRHNTALRRSTARPGDEIWVTGTIGDAALGLLVLQGSLQDP 189

Query: 194 GELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
              +++   L      L     V A  D +  G+       A   G  + +   A+PV  
Sbjct: 190 SGFLAERYHLPRPRTGLHLHGIVSAAMDISD-GLIQDCGHIAEESGVQLVVDAEAVPVSS 248

Query: 254 AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           A   +     +  L   ++ +L++      +  + AA  +         IG V    GVR
Sbjct: 249 AAASLGHEWLMRRLCGGDDYELLLTCAPERSAALQAACQAAE--VPVHRIGTVRTGSGVR 306

Query: 314 LAGLYGVKRT 323
           L    G +  
Sbjct: 307 LLDGEGHEIV 316


>UniRef50_D2RDT5 Hydrogenase expression/formation protein HypE n=3
           Tax=Archaeoglobaceae RepID=D2RDT5_ARCPR
          Length = 344

 Score =  230 bits (586), Expect = 8e-59,   Method: Composition-based stats.
 Identities = 113/350 (32%), Positives = 176/350 (50%), Gaps = 25/350 (7%)

Query: 4   IQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           I+   G+GG+ M + +    +  F +  L E       D     ++ D   F+TDSYV+ 
Sbjct: 3   IRREDGAGGKYMAEFLKKHIISRFGDNRLGEISLADMDD----SSDFDGYVFTTDSYVVS 58

Query: 64  PLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAA 123
           P  F GG+IG LA+CGTAND+AV GA P  +S   I++EG  +   + ++  +    +  
Sbjct: 59  PPIFRGGSIGSLAVCGTANDLAVMGAKPYAMSLALIIQEGFKVSDFEKIMNDVERWVKEL 118

Query: 124 GIAIVTGDTKVVQRGAVDKLFINTAGMGAIP----------------ANIHWGAQTLTAG 167
            + ++TGDTKVV      ++  NT+G+G                            L  G
Sbjct: 119 DVKLITGDTKVVSANV--EIIANTSGIGIRNSALDHNISVVKEYRDYPYNWVRDCGLREG 176

Query: 168 DVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGV 227
           D ++VSG + DH   I+  RE    D ++ SD   +   ++   ++ G+ A++D TRGG+
Sbjct: 177 DAIIVSGCVADHAVAIMLSRE-FDFDIDVQSDVYPVWLFVKEALEVGGITAMKDPTRGGL 235

Query: 228 NAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQV 287
              ++E A   G GI + E  +P++  V+G CE+LGLD L+ ANEGK+V+ V  + AE V
Sbjct: 236 ANALNELAEKSGVGIYIEEERIPIREEVKGFCEVLGLDPLSMANEGKVVMGVVEDMAEDV 295

Query: 288 LAALHSHPLGKDAALIGEVVERKGVRLAGLY-GVKRTLDLPHAEPLPRIC 336
           L ALH       A +IG         +     G K+ L  P A+P+PR+C
Sbjct: 296 LKALHKAGQKY-AEIIGYATSEFEEVVVETEIGTKKVLPPPTADPIPRVC 344


>UniRef50_A4J8J0 Thiamine-monophosphate kinase n=1 Tax=Desulfotomaculum reducens
           MI-1 RepID=A4J8J0_DESRM
          Length = 334

 Score =  229 bits (585), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 73/324 (22%), Positives = 118/324 (36%), Gaps = 26/324 (8%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRL-AFSTDSYVIDPLF----FPGGNI 72
           LI+ L      +P   +       D A L   G +    +TD  + +  F         +
Sbjct: 12  LIDLLNKNMLYDP--EKVIAGIGDDAAVLKPPGTKWQLLTTDMMMENIHFRLDWSQYYQV 69

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +DVA  G  P +      + E   +E ++ +   + E A    + +V GDT
Sbjct: 70  GYKALAVNISDVAAMGGYPSHAVVSVGIPEETRVEDIEELYRGLKEMACRFKVNLVGGDT 129

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L IN A MG +             GD++  +G LG   A +  L      
Sbjct: 130 VKSPG----PLVINIALMGEVEEGRAVFRSGAKPGDLIYTTGFLGTSAAGLYILSHNGDY 185

Query: 193 DGELVSD-------CAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
             EL                  + L ++ GV AL D +  G+ A + E   A   G  + 
Sbjct: 186 PVELKEKVIRSHLLPEPRVAAARILSELEGVTALDDNSD-GLAAELREICRASSAGCLIR 244

Query: 246 EAALPVKPAVRGVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           E +LPV P V  +  L G + L++      + +L+  +     E +  AL     G    
Sbjct: 245 EKSLPVLPEVEQLACLTGRNTLDWIMDGGEDYELLFTLRPERQEYIENALGKE--GILYK 302

Query: 302 LIGEVV-ERKGVRLAGLYGVKRTL 324
            IG +    +G+ L    G K T+
Sbjct: 303 AIGIITHSSEGMVLEKEDGAKETI 326


>UniRef50_A5N2W0 HypE n=8 Tax=Clostridium RepID=A5N2W0_CLOK5
          Length = 329

 Score =  228 bits (583), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 65/331 (19%), Positives = 129/331 (38%), Gaps = 23/331 (6%)

Query: 12  GQAMQQLINSLF-MEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+   + + S+                    D + +         STD     P+     
Sbjct: 4   GKLDWKDLKSIIDKNRSVERNDVRVRSGIGEDCSVINFGDKECVVSTD-----PITGANI 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           N G+LA+    ND+A  G  P  L    +L EG  +E +  ++  +++ A+   + I+ G
Sbjct: 59  NSGRLAVHINCNDIASCGIEPVGLLVTILLPEGASLEDINRLMGEISDEAKKLNVEILGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T+V    AV+K+ I+   +G                D ++ +  L   G +I+    + 
Sbjct: 119 HTEVTS--AVNKIVISCTAIGKGDKGKAVSTSGAKEKDDIVATKCLCLEGTSIIVNDYED 176

Query: 191 G----LDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACGCG 241
                L  E +++       I  +++       GV ++ D T GG+   + E A A   G
Sbjct: 177 KLIGLLTKEEINEAKNYIKQISVVKEGILSGGFGVNSMHDITEGGILGALWEIAEASRVG 236

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
            ++ +  LP+      +C    +D L   + G ++I   +   E+++  L +   G  A 
Sbjct: 237 FKVYKDKLPITKITEKICGHYLIDPLKLISSGSMLITTPKG--EELVRMLENE--GIKAC 292

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           ++GE+ +     +    G +  +D P  + L
Sbjct: 293 VVGEITKGGYKLI--CNGEEEEIDAPGRDEL 321


>UniRef50_Q2RKM3 AIR synthase related protein-like n=1 Tax=Moorella thermoacetica
           ATCC 39073 RepID=Q2RKM3_MOOTA
          Length = 528

 Score =  228 bits (582), Expect = 2e-58,   Method: Composition-based stats.
 Identities = 83/338 (24%), Positives = 132/338 (39%), Gaps = 26/338 (7%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQA------RLDLAQLVAEGDRLAFSTDSYVIDPLFFP 68
           M   ++  F      P     + +        +D A L    + LA + D     P    
Sbjct: 1   MIGKVDDAFFRQAILPHTGAGDPEVVVGPRMGVDAAVLKIGEEYLAVAEDPIFPGP-TTS 59

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
             + G + +   A+DVAV G  PR+++   +L  G P + +  +V S++  AR  GI IV
Sbjct: 60  PDDFGWITVHIGASDVAVMGIKPRFMTYSLLLPPGTPEDYIAGLVRSISTYARELGITIV 119

Query: 129 TGDTKVVQRGAVDKLFIN-TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR 187
            G T     GAV    I      G               GD ++++       A ++   
Sbjct: 120 GGHTGFY--GAVTIPTIGGITVWGR--GREVVTPAGARVGDAVIITKGAAIEAAALVACE 175

Query: 188 EQLGL-----DGELVSDCAVLTPLIQTLRDIP------GVKALRDATRGGVNAVVHEFAA 236
               L       +LV+        +  + +        GV A+ DAT GG+   + E A 
Sbjct: 176 LGEKLLAAGISPDLVARAKKRLREMSVVAEAGIAVEVGGVHAMHDATEGGLARGLWEVAE 235

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
           A G G+ +  A +PV   +R VC+ +GL+     +EG LV+      A+ +LAA      
Sbjct: 236 ASGVGLRIERARVPVPADIRAVCDYIGLNPYEVISEGTLVLTCAPEKADAMLAAFKEA-- 293

Query: 297 GKDAALIGEVV-ERKGVRLAGLYGVKRTLDLPHAEPLP 333
           G +AA+IG VV    G       G +  L  P  +   
Sbjct: 294 GIEAAVIGRVVPAGAGRAWLEDDGREEQLLPPAVDRFW 331


>UniRef50_O05514 Thiamine-monophosphate kinase n=5 Tax=Bacillus RepID=THIL_BACSU
          Length = 325

 Score =  228 bits (581), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 25/316 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLF----FPGGN 71
            LI+S+      +   +  +     D A   A+ G +     D+ V D  F        +
Sbjct: 5   DLIHSITPRTIHH---SSVDVGIGDDAALYTAKHGVQEIVCVDTMVEDVHFKLHYSSPED 61

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           IG  A+    +D+A  G IP++      +        +KA+   M E A+   + ++ GD
Sbjct: 62  IGYKALAVNISDIAAMGGIPKFYLVSLAVPSKWTESEIKAMYEGMNELAKLYHMDLIGGD 121

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T        DKL +    +G I              D++ V+G +G   A +  L E+  
Sbjct: 122 TVST----ADKLVVTVTVIGEIEKGQACLRSLAKPNDIVFVTGEIGSSAAGLSLLLEETN 177

Query: 192 LDGE------LVSDCAVLTPLIQ--TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
                      +       P +    L  I    AL D +  G+ + ++E A A    IE
Sbjct: 178 PQNSSVETDYFIHRHKRPEPRVSVGRLCSIFKRAALNDVSD-GLASELNEIAEASCVSIE 236

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + E+ LP+   +  +       AL    + +L   V     E +     +  L      I
Sbjct: 237 IVESMLPIHSDLPKLHPNWKEWALFGGEDFELTGTVSNEEWEVLKQECAA--LHLPITKI 294

Query: 304 GEVVE--RKGVRLAGL 317
           G V E  +  V L   
Sbjct: 295 GYVREKTKSKVILKTD 310


>UniRef50_C4LAD9 Thiamine-monophosphate kinase n=1 Tax=Tolumonas auensis DSM 9187
           RepID=C4LAD9_TOLAT
          Length = 328

 Score =  228 bits (581), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 73/319 (22%), Positives = 116/319 (36%), Gaps = 23/319 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFF---PGGNI 72
           +LI   F    A    A+ E     D A L V  G+ LA STD+ V D  FF       +
Sbjct: 5   ELIQHYFAAQAA--ARADVELGIGDDCALLNVPVGECLAVSTDTLVSDVHFFADVDPVAL 62

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA PR++S    L +   +  L          A    +A++ GDT
Sbjct: 63  GHKALAVNLSDLAAMGAQPRWISLALTLPKADDV-WLTGFTQGFHALAVKHNVALIGGDT 121

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I  +  G +PA          AGD + VSG+LG     +      L +
Sbjct: 122 TRGP------LSITISAKGTVPAAQALRRSGAKAGDAIYVSGSLGAAALAVQQRIHNLPI 175

Query: 193 DGELVSDC----AVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           + + + DC        P  +    + G+  +  D +  G++  +     A G   E+   
Sbjct: 176 NSDALRDCSFRMDYPQPRCELGLALRGIATSALDLSD-GLSGDLMHILRASGVAAEIELT 234

Query: 248 ALPVKPAVRG--VCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
            LP+  AV+     E     AL   ++ +L   V       +     +  L      IG 
Sbjct: 235 NLPIASAVQRSVTPEQALQLALGGGDDYELCFTVPAGHETAISEL--AVALDLPLTRIGT 292

Query: 306 VVERKGVRLAGLYGVKRTL 324
           +   +   +    G    L
Sbjct: 293 ITTGEPQIIWYHQGKAVEL 311


>UniRef50_Q8K9A5 Thiamine-monophosphate kinase n=4 Tax=Buchnera aphidicola
           RepID=THIL_BUCAP
          Length = 323

 Score =  227 bits (579), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 54/314 (17%), Positives = 115/314 (36%), Gaps = 29/314 (9%)

Query: 17  QLINSLFM---EAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGG 70
           ++I+  F    +   N      +D A +     + + + LA STD+ V    F       
Sbjct: 7   EIISKFFKNHQKKDKNQIKGIGDDSALIK----IPKNNLLAISTDTLVEGKHFLKNITPK 62

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++   ++    +D+A  GA P +++    + +   +  LK+   S  +      + ++ G
Sbjct: 63  DLAYKSVAVNLSDLAAMGAKPTWITLSITMPKSDSV-WLKSFSKSFFKILNKYKLNLIGG 121

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L I  +  G I             GD++ ++G LG+  A +  L+++ 
Sbjct: 122 DTNSGP------LSITLSIYGLIEGKNALLRGNAKNGDLIYITGNLGESAAGLSLLQKKT 175

Query: 191 GLDGE-----LVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIEL 244
            L        L+       P I     +  +  A  D +  G+ + +        CG ++
Sbjct: 176 FLKNVKICNYLIKKHLKPIPRISEGIALRNIANAAIDISD-GLISDLGHILKNSKCGADI 234

Query: 245 SEAALPVKPAVRGV--CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           +   +P+   +      +     ALN   + +L   + +   +++  A+           
Sbjct: 235 NLNTIPISKILTDNFKIDEYLNWALNSGEDYELCFTISKKNIKKLNVAIKKKI--IKCTC 292

Query: 303 IGEVV-ERKGVRLA 315
           IG +    KG+ L 
Sbjct: 293 IGYITSAEKGLNLI 306


>UniRef50_C9YEU1 Thiamine-monophosphate kinase n=1 Tax=Curvibacter putative symbiont
           of Hydra magnipapillata RepID=C9YEU1_9BURK
          Length = 354

 Score =  227 bits (579), Expect = 5e-58,   Method: Composition-based stats.
 Identities = 74/338 (21%), Positives = 107/338 (31%), Gaps = 34/338 (10%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVA-EGDRLAFSTDSYVIDPLFFP---GGNIG 73
           LI   F E   +P   +       D A L    G + A S+D  V    FF       +G
Sbjct: 26  LIARYF-ERSQHPLPTQVVLGIGDDCALLQPTPGMQWAISSDMLVSGRHFFADVNPLTLG 84

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A+    +D+A  GA P   +    L +      L+     +   A A    +V GDT 
Sbjct: 85  HKALAVNLSDLAACGARPVGFTLALSLPDA-DPAWLQGFSQGLFALADAHNCPLVGGDTT 143

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
                    L I     G  P           AGD + VSGTLGD    +  L  +  L 
Sbjct: 144 RGP------LNICITVFGETPPGQALLRSGARAGDDIWVSGTLGDAALALHCLWGRDQLP 197

Query: 194 GELVS----DCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELS-EA 247
            E  +         TP     + + G+  A  D +  G+   +         G EL    
Sbjct: 198 AEAFALARQRLEQPTPRAALGQALRGIATAAADVSD-GLLGDLGHILERSHVGAELEALY 256

Query: 248 ALPVKPAVRGVCELLG-LDA------------LNFANEGKLVIAVERNAAEQVLAALHSH 294
           A+ +  A   +    G  D             L+  ++ +LV         QV AA    
Sbjct: 257 AINLLAARAYLTGASGTFDPNSQTDSTALRYVLSGGDDYELVFTAAPEHRLQVQAA--GT 314

Query: 295 PLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
             G     IG +V   GV +    G          +  
Sbjct: 315 HSGTPVTRIGRIVRDPGVTVKAPDGSALRGPWASFDHF 352


>UniRef50_Q0K6Z2 Thiamine monophosphate kinase n=114 Tax=Proteobacteria
           RepID=Q0K6Z2_RALEH
          Length = 381

 Score =  226 bits (578), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 72/325 (22%), Positives = 113/325 (34%), Gaps = 24/325 (7%)

Query: 5   QLAHGSGGQAMQ-QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
            ++H       +  LI   F        L   +D A ++       G  LA STD  V  
Sbjct: 55  TMSHAQPAPLSEFDLIRRFFTRPVRKAALGVGDDCALIE----GRPGHHLAISTDMLVSG 110

Query: 64  PLFFP---GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
             FFP     ++G  A+    +D+A  GA PR  +    L E      L  +   M   A
Sbjct: 111 RHFFPDVAPRSLGHKALAVNLSDLAAMGAEPRAFTLALALPEA-DPAWLAELADGMLALA 169

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
            A G  +V GDT          L ++    G +P            GD + +SGTLGD  
Sbjct: 170 DAHGCELVGGDTTRGP------LTLSLTVFGDVPLRAALRRDAARPGDDIWISGTLGDAR 223

Query: 181 ATILNLREQLGLDGELVSDCAV----LTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFA 235
             + + R +  L     S         TP +     + GV  A  D +  G+   +    
Sbjct: 224 LALGDCRGEWLLPEPEFSQVRPRMDTPTPRVALGMALRGVAHAALDISD-GLVGDLGHIL 282

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSH 294
                G  +   ALP    +    + +  +  L   ++ +L       + + + A   S 
Sbjct: 283 ERSQVGALVDVDALPRSAVLASQPDAIQRECVLAGGDDYELCFTAPAGSRDAIAAI--SE 340

Query: 295 PLGKDAALIGEVVERKGVRLAGLYG 319
            L    A +G +    G+RL    G
Sbjct: 341 RLALPLARVGAITPEPGLRLVDSTG 365


>UniRef50_D1C275 Thiamine-monophosphate kinase n=1 Tax=Sphaerobacter thermophilus
           DSM 20745 RepID=D1C275_SPHTD
          Length = 342

 Score =  226 bits (578), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 63/336 (18%), Positives = 116/336 (34%), Gaps = 26/336 (7%)

Query: 10  SGGQAMQQL----INSLFMEAFANPWLAEQEDQARLDLAQLVA-EGDRLAFSTDSYVIDP 64
           SGG+ ++++    +  +     +             D A      G  L F+TD  V + 
Sbjct: 5   SGGRPVKEVGEFPLIDMIDGVVSATLPRRLRMGIGDDAAVWRPRPGRDLVFTTDILVQNV 64

Query: 65  LF----FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            F         +G  A+    +DVA  GA PR       L        +  +   M    
Sbjct: 65  HFRLDWMDWQAVGHKALAVNLSDVAAMGAQPRLALVSLALTGSERDREVTDLFRGMNALG 124

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI--HWGAQTLTAGDVLLVSGTLGD 178
           R  G+ +  GD      G    + ++   +G   A             GD++ V+G LG 
Sbjct: 125 RRHGVVVAGGDLSASPNG----VIVSVTVIGETSAGRRAVMTRDGARPGDIIGVTGPLGM 180

Query: 179 HGATILNLREQ---LGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHE 233
             A +   ++Q   L  +  +    +   P ++   L    GV+A  D +  G+   + +
Sbjct: 181 AAAGLRVFQQQLLTLDGNPAMREAYSRPKPRVREGRLLARAGVRAAMDLSD-GLLGDLPK 239

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHS 293
              A G    +  A +P+  A++   +     AL    + +L+         +V  A   
Sbjct: 240 MCQASGVSAVIDIARVPIPNAIKWNFDDWFDLALRGGEDYELLFTAPPAVFARVCRAFRL 299

Query: 294 HPLGKDAALIGEVV----ERKGVRLAGLYGVKRTLD 325
             L      IGE+V    +   V++    G    ++
Sbjct: 300 AGLHGP-WRIGEIVKAGAKGPEVKIREASGKVEEVE 334


>UniRef50_C7R8N3 Thiamine-monophosphate kinase n=1 Tax=Kangiella koreensis DSM 16069
           RepID=C7R8N3_KANKD
          Length = 323

 Score =  226 bits (578), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 61/312 (19%), Positives = 112/312 (35%), Gaps = 26/312 (8%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYVIDPLFF---PGGNI 72
           +LI   F  +F+        +    D A L     R L  S D+ V    FF      +I
Sbjct: 5   ELIKEYF--SFSQSKSDTVVEGIGDDCAVLSVPDKRQLVTSVDTLVDGVHFFSDSDPADI 62

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
              ++    +D+A  GA P   +    L + +    LK+    + E +    I ++ GDT
Sbjct: 63  AYKSLAVNVSDLAAMGAKPLGFTLAIALPK-VDEVWLKSFSKGLQEASADFEIPLIGGDT 121

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-- 190
                     L I    +G++ A+     ++    D + V+G +GD  A +    +    
Sbjct: 122 TQGP------LTITVNVLGSVKADKAMLRKSAQLDDDIWVTGYVGDAAAALGLHGKAQSS 175

Query: 191 ---GLDGELVSDCAVLTPLIQ-TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
                +  L+       P I    +      A  D +  G+ A +        C  ++  
Sbjct: 176 DLNEAESYLLQRLLRPNPPITFATKLAKLAHAAIDISD-GLLADLGHILEQSQCSAKIKV 234

Query: 247 AALPVKPAVRGV--CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
            +LP+   +      E     ALN  ++ +L    + +   ++L    +     +   IG
Sbjct: 235 GSLPLSEQLIQCVGLEQAREFALNGGDDYELCFTAKHSMRNKILNL--AEDFQVNVHRIG 292

Query: 305 EVVE--RKGVRL 314
            +VE   +GV L
Sbjct: 293 TIVEQSDEGVFL 304


>UniRef50_Q5QVE6 Thiamine monophosphate kinase n=2 Tax=Idiomarina RepID=Q5QVE6_IDILO
          Length = 331

 Score =  226 bits (578), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 62/318 (19%), Positives = 110/318 (34%), Gaps = 21/318 (6%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVA-EGDRLAFSTDSYVIDPLFF---PGGNI 72
            LIN  F     +    +       D A +       L   TD+ V    F    P   I
Sbjct: 7   SLINEYF--THRSAKRGDVAMGIGDDGAVVRPMPEHDLVIVTDTLVEGVHFDMTTPPRAI 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  ++    +D+A  GA P ++S    L   +  + L+     + E        ++ GDT
Sbjct: 65  GHKSVAVNLSDLAAMGAQPCWISLALTLPR-MDEDWLQEFSGGLDEICSYYDCQLIGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I     G +P+          AGD + VSG+LGD G  +   + ++  
Sbjct: 124 TKGP------LTITITAHGQLPSGSAIPRSGAKAGDWIYVSGSLGDAGLGLQVTQNKVST 177

Query: 193 DGE----LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
            G     ++      TP +   + + GV +       G+ A +       G   +L    
Sbjct: 178 TGRHLQQVIERLHYPTPRVALGQSLRGVASSCIDISDGLLADLRHLMTEAGTQAQLELEK 237

Query: 249 LPVKPAVRGVCELLGLDALNF--ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           LP+  A+    ++    AL     ++ +L   +      + +  L +H   +    IG V
Sbjct: 238 LPLSLALTETLQVDDALALALTAGDDYELCFTLPEEHRGR-METLTTHLKTRPV-CIGRV 295

Query: 307 VERKGVRLAGLYGVKRTL 324
              +   +   Y  +  L
Sbjct: 296 ANGESGDIQLRYNGEDWL 313


>UniRef50_Q1IHF6 Thiamine-monophosphate kinase n=1 Tax=Candidatus Koribacter
           versatilis Ellin345 RepID=Q1IHF6_ACIBL
          Length = 318

 Score =  226 bits (576), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 64/328 (19%), Positives = 108/328 (32%), Gaps = 31/328 (9%)

Query: 16  QQLINSLFME----AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---- 67
           + LI  +        F+       +D A LD       G  L  +TD  + +  F     
Sbjct: 6   RALIERIRRRASSRKFSAITRGIGDDCAVLD----PPPGHELLVTTDFCLENVHFRREWH 61

Query: 68  PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAI 127
           P   +G   +    +D+A  G  P        L   +P + +      +   A    + +
Sbjct: 62  PAKAVGHRCLVRGLSDIAAMGGDPLAAFLSLALPAEIPQKWVDGFFDGLLALAERWKVPL 121

Query: 128 VTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR 187
             GD     +G    +  +   +G++P            GDVL V+GTLG   A +   R
Sbjct: 122 AGGDIAQSPQG----VMADIMVLGSVPRGKAILRSGGKPGDVLYVTGTLGLSVAALQAFR 177

Query: 188 EQLGLDGELVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
                  +         P I   + LR+     A+ D +  G++  +       G G  +
Sbjct: 178 AGKKPTAKSTPRHFFPDPRIDIGRLLRERKLATAMIDLSD-GLSTDLSHICDESGVGAVV 236

Query: 245 SEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
              ++P         E     ALN   + +L+            A +     G     IG
Sbjct: 237 YATSVPYVGG-----ENGLEFALNGGEDYELLFTANP------RARVPKEIDGVPVTAIG 285

Query: 305 EVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           E+V+R+G+ L    G    L     E  
Sbjct: 286 EIVQRRGMWLEDKRGKVAKLRPRGWEHF 313


>UniRef50_Q5FH10 Thiamine-monophosphate kinase n=4 Tax=canis group
           RepID=Q5FH10_EHRRG
          Length = 316

 Score =  225 bits (575), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 55/295 (18%), Positives = 105/295 (35%), Gaps = 15/295 (5%)

Query: 39  ARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGKLAICGTANDVAVSGAIPRYLS 95
              D A +    ++L  + D  + +  F        + K A+    +D+A  GAIP    
Sbjct: 20  IGDDAAIINCTENQLVVTKDILIEEVHFLKNCKPRILAKKALRSNLSDIAAMGAIPYAYC 79

Query: 96  CGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPA 155
            G +L   +     +    S+ E  +   I ++ GDT   +    + + I+    G I  
Sbjct: 80  LGLVLPNNISNNWWQDFSNSLREEHKIFDIILLGGDTTSHKN---NIIIISITAFG-INH 135

Query: 156 NIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE-LVSDCAVLTPLIQTLRDIP 214
                      GD + VSGT+GD    +L  +  +  + E L +   +  P I    DI 
Sbjct: 136 GNLLKRSGAKIGDFIYVSGTIGDAALGLLVYQNIIKKNYENLKNKYDIPQPRINLGIDIN 195

Query: 215 GV-KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGV---CELLGLDALNFA 270
            +  +  D +  G+   +     A   G  +    +P+    + +           L+  
Sbjct: 196 QIASSCIDISD-GLIQDMEHICHASNVGASIYLNKIPLSNETKEIIANTPRYINSVLSGG 254

Query: 271 NEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLD 325
           ++ +L+       ++ +      +  G     IG++ E   V L        TLD
Sbjct: 255 DDYELIFTANPKFSDSIKEISKKN--GVKITKIGKITEGNSVILYDHSNNIVTLD 307


>UniRef50_Q46DN9 Thiamin-monophosphate kinase n=4 Tax=Methanosarcinaceae
           RepID=Q46DN9_METBF
          Length = 340

 Score =  225 bits (575), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 61/328 (18%), Positives = 117/328 (35%), Gaps = 26/328 (7%)

Query: 11  GGQAMQQLINSLFMEAFANPWL--AEQEDQARLDLAQLVAEGDR-LAFSTDSYVIDPLF- 66
           G +A+  +++ +F                    D A L  +G+  L  +TD       F 
Sbjct: 10  GERALISILSEIFKAPDGREKEQEGILIGAGSDDCAVLDLKGEDCLVVTTDMLHRTTDFP 69

Query: 67  --FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAG 124
                  IG ++     +D+A  GA P  L     +     +  ++A+   M       G
Sbjct: 70  EEMTPWQIGWMSAAVNLSDIAAMGAEPTGLVMAIGMPADTEIAFVEALAKGMQACTEFCG 129

Query: 125 IAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL 184
             I+ GD          +L I    +G +  +     +    GD++ V+G  G  GA + 
Sbjct: 130 TMIIGGDLDTHT-----ELTITGTALGRVKKSQLLLRRGARPGDLVCVTGYTGSAGAALE 184

Query: 185 NLREQLGLDGELVSDCAVLTPL---IQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            L+    +   ++       P     + L +   V ++ D T  G+   +++ +     G
Sbjct: 185 ALQSGKPVSETVLKALFEPVPRTKEARKLAESGAVTSMMD-TSDGLAMSLYDLSRQSRVG 243

Query: 242 IELSEAALPVKPAVRGVC---ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             + E ALPV   VR        L   +L    + +L+I ++    ++V           
Sbjct: 244 FMIRENALPVLREVRKFASNPNRLREFSLYTGGDFELLITIDPQKIKKVQNIC------- 296

Query: 299 DAALIGEVVE-RKGVRLAGLYGVKRTLD 325
           +  +IGE  +   G+ L        T++
Sbjct: 297 NLVVIGECTKYEAGIVLESPECEHITIE 324


>UniRef50_A7BRC9 Thiamine-monophosphate kinase n=1 Tax=Beggiatoa sp. PS
           RepID=A7BRC9_9GAMM
          Length = 351

 Score =  225 bits (574), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 65/342 (19%), Positives = 113/342 (33%), Gaps = 59/342 (17%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGD-RLAFSTDSYVIDPLF---FPGGNI 72
            +I   F + F  P   +       D A        +LA S D+ V    F       +I
Sbjct: 5   DVIAHYFSQNF--PKRTDVILGIGDDAALCSVPNYMQLAVSIDTLVEGVHFPVTTSPEDI 62

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P +++      + +    LK     + E A++A ++++ GDT
Sbjct: 63  GYKALAVNLSDMAAMGATPAWMTLALTCPK-VNETWLKRFSQGLLELAQSAQVSLIGGDT 121

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I     G +P            GD + V+GTLGD G  +  ++E   +
Sbjct: 122 TQGP------LTITLQISGFVPIGQALRRDGAQPGDGIYVTGTLGDAGLGLALIQETEKI 175

Query: 193 DGELVS--DCAVLTPLIQTL-------------------------------------RDI 213
             +      C   +P+++ L                                        
Sbjct: 176 FPKEREAPRCDPPSPVVERLVSLSNHIETWEGVRGRAASKFVKSRLNRPTPCLKIGQALR 235

Query: 214 PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGV--CELLGLDALNFAN 271
               +  D +  G+ A +     A   G  L    LP+   +      E     AL+  +
Sbjct: 236 GIASSAIDISD-GLVADLGHILKASSVGATLQLENLPLSNVLHDYLSLEQAWYFALSAGD 294

Query: 272 EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
           + +L   V  N  + +  AL +         IG +    G+R
Sbjct: 295 DYELCFTVPPNKEKALQEALETETY----TRIGSIETESGLR 332


>UniRef50_C0CMS4 Putative uncharacterized protein n=2 Tax=Clostridiales
           RepID=C0CMS4_9FIRM
          Length = 339

 Score =  225 bits (573), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 77/335 (22%), Positives = 130/335 (38%), Gaps = 23/335 (6%)

Query: 12  GQAMQQ-LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRL-AFSTDSYVIDPLFFPG 69
           G+  +Q L+ S+  +                D A L    D +   S+D     P+    
Sbjct: 4   GKLPEQVLVRSVIKKISHRRDEVLFGPGVGRDCAALKLAKDEIFVISSD-----PITGTV 58

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            +IG   I  TAND+A +GA P  +    +L      + L+ +V  M +T  A  + ++ 
Sbjct: 59  KDIGSHCIYITANDLAAAGAEPVAVMVTALLPPETEEKDLRGIVEDMEKTCAALDMEVIG 118

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           G T+V     V +  ++  G+G + A      + L AG  L+V+  +G  G +I+     
Sbjct: 119 GHTEVTD--TVKQPLLSVTGVGKMKAGEALYEKKLKAGQDLVVTKWIGLEGTSIVAKERA 176

Query: 190 LG----LDGELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGC 240
                      V         +  L +       GV  + D T GGV   + E A     
Sbjct: 177 QKLREVFAESFVRTAQNFDQYLSVLPESRIAMEHGVSVMHDITEGGVFGALWELAQGADV 236

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G+++    +P++     VCE  GL+     + G ++I       E ++  L     G   
Sbjct: 237 GLDVDLKKIPIRQETVEVCEQFGLNPYLLMSSGAMLIGT--EQGEILVRKLQEA--GIPG 292

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
            +IG+ VE     L       R LD P ++ L +I
Sbjct: 293 TVIGQAVEGSSRILRNGE-EIRYLDRPQSDELYKI 326


>UniRef50_D1VUU5 Hydrogenase maturation factor n=1 Tax=Peptoniphilus lacrimalis
           315-B RepID=D1VUU5_9FIRM
          Length = 325

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 72/331 (21%), Positives = 125/331 (37%), Gaps = 17/331 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQ-ARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+     +     +   +            +D A L   GD +  S D     P+     
Sbjct: 4   GKVSNNDLEKYVFKNINSHRKEVLTKSSIGIDTAVLDFNGDLIVTSVD-----PITGANK 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           N+G LAI  + NDV+  GA P  +    +L     +E L  ++       R   + I+ G
Sbjct: 59  NLGYLAINISVNDVSCQGADPVGVLISILLPAESKLEDLNKIMEDADRACRQNNLEIIGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T+V    AV+K+ + T  +  +  N      ++  GDV+ VS  +G  G +I+   +  
Sbjct: 119 HTEVTD--AVNKIVLTTTVIARVNKNKMPKISSIKVGDVIAVSKDIGLEGTSIILEEKGN 176

Query: 191 GLDGELVSDCAVL-TPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAACGCGIEL 244
               E       +    +  LR+        VK + D T GG+   + E + A G GIE+
Sbjct: 177 EFLSEDELRKESIDIKDLSVLREAKIAVDFNVKYMHDVTEGGIYGALWECSEAIGKGIEV 236

Query: 245 SEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
               +PVK   + +     ++     + G +++   +   +    A            IG
Sbjct: 237 DNIKIPVKDVTKKIGSHYNINIYGLISSGSMLMVFNKEDFKAYKKAC--FEKNIKITQIG 294

Query: 305 EVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           EV E     L    G K  +  P ++ L +I
Sbjct: 295 EVTEENKKILID-NGKKIEIPEPASDELYKI 324


>UniRef50_O27447 Probable thiamine-monophosphate kinase n=1 Tax=Methanothermobacter
           thermautotrophicus str. Delta H RepID=THIL_METTH
          Length = 327

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 62/332 (18%), Positives = 125/332 (37%), Gaps = 31/332 (9%)

Query: 13  QAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG-- 70
           + + ++I+       ++  +   +D A +D        + L  ++D  +    F      
Sbjct: 12  KLISRIISRARSVFGSSEVMGLGDDAALIDAG-----EEFLVLTSDLLLETRHFPDPERP 66

Query: 71  -NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            ++G   +    +D+A  G+ P        L   L +E   +++  + E        ++ 
Sbjct: 67  RDMGWKTVTVNMSDLAAMGSRPEGFILSVALP-DLELEFFDSLMDGVIEACCHYQAPLIG 125

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT---ILNL 186
           GDT        D++ ++   +G    ++         GD++ V+G LG   A    IL+ 
Sbjct: 126 GDTN-----EADEIILSGTAIGRAEKDMVLMKSGARPGDLVAVTGPLGVGAAGTELILSG 180

Query: 187 REQLGLDGELVSDCAVLTPLIQ--TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
           R+  G +  +      +  + +   L +   V +  D T  G+ + + E   A G G+ +
Sbjct: 181 RDTGGFENAVERSLRPVARIEEGLILAESGLVSSATDITD-GLVSELGELMDASGTGMRI 239

Query: 245 SEAALPVKPAVRGVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
            E  LP+   V  +  +LG D L        + +LV        E++   +         
Sbjct: 240 YEDRLPLGREVPEIASILGRDPLELALYYGEDFELVFTAPPTGMEELSDMME-------L 292

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
            +IGEV    G+ +    GV   L +   E L
Sbjct: 293 HVIGEVTVGGGIEMVDKDGVTYKLHVRGYEHL 324


>UniRef50_C5A3X6 Thiamine monophosphate kinase (ThiL) n=4 Tax=Thermococcus
           RepID=C5A3X6_THEGJ
          Length = 319

 Score =  224 bits (572), Expect = 3e-57,   Method: Composition-based stats.
 Identities = 70/330 (21%), Positives = 113/330 (34%), Gaps = 32/330 (9%)

Query: 14  AMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID---PLFFPGG 70
            M+  I  LF+           +     D   L      L  + D  V     P      
Sbjct: 1   MMESEIIELFIRHLKRQ----GDLPLGDDAGALRLGDRWLVATNDMLVRKTDVPDIMTPE 56

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G  A+    +D+A  GA P        +   L  + L+ +   + E     G+ +++ 
Sbjct: 57  QVGFKAVTMNVSDMASMGAEPLGFLFSLGIPGDLDSDYLEGIARGIGEALDFYGLPVLSA 116

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT        D L I+ A +G               G+++ V+G LG   A  L  +  L
Sbjct: 117 DTN-----EADDLIIDGAALGITE--RLLTRSGAKPGELVCVTGDLGRALAGYLVWKNGL 169

Query: 191 GLDGELVSDCA----VLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
            +   +              ++   ++  V +       G+   ++  A     GIE+  
Sbjct: 170 EVSDAVRKPLYEKFLEPRARVREGSELSKVASSAIDISDGLAKELYLLAEMSQVGIEVRP 229

Query: 247 AALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
            +LP+   V  V ELLGLD     L    E +LV  V     E +           D ++
Sbjct: 230 ESLPLGKGVEEVAELLGLDPFEIALASGEEFELVFTVAPEFVESL---------NFDFSV 280

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           IG V   KG+ L    G KR +     E L
Sbjct: 281 IGRVTRGKGIYLVDDSG-KRVMPKLGWEHL 309


>UniRef50_C8WRZ3 Thiamine-monophosphate kinase n=2 Tax=Alicyclobacillus
           acidocaldarius RepID=C8WRZ3_ALIAD
          Length = 323

 Score =  224 bits (571), Expect = 4e-57,   Method: Composition-based stats.
 Identities = 77/315 (24%), Positives = 125/315 (39%), Gaps = 26/315 (8%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIG 73
           LI +L  +    P  A+       D A +   G RLA +TD+ V    F         +G
Sbjct: 6   LIQALVAKL--PPPGADVMVPIGDDCAVVD-GGGRLAVTTDAVVEGVHFRRDTMSPPQMG 62

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A+    +D+A  G  P +++    +    P E + A+   ++E A A G ++V GD  
Sbjct: 63  YRAMAAAVSDIAAMGGQPAWITVALAVPPSWPQEDVVAIYDGVSEAAAAFGASVVGGDVV 122

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG-- 191
             Q      L+++   +G +             GDVL V+G+LG   A +  L  +    
Sbjct: 123 STQG----PLWMSITAVGRVE--RPVTRAGARPGDVLFVTGSLGGSAAGLDILLGRRAGS 176

Query: 192 --LDGELVSDCAVLTPLIQTLRDIP--GVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
                 LV      TP I   R+    G  AL D +  G+ + ++E A A G  +     
Sbjct: 177 AIAQAVLVERHRRPTPRIAFGREAARLGATALDDISD-GLASELNEIAEASGVRLLFEGD 235

Query: 248 ALPVKPAVRGVCELLGLDALN----FANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
            +P++P V      +G D L        + +LV    R+   ++LA   +  +G     I
Sbjct: 236 RVPIQPEVTEYARAVGKDPLEYALFGGEDYELVGTAPRDVFARLLAV--APVVGTPITAI 293

Query: 304 GEVVERKGVRLAGLY 318
           G V E  GV +    
Sbjct: 294 GRVEEGDGVVMRRDG 308


>UniRef50_C7JHE3 Thiamine monophosphate kinase n=8 Tax=Acetobacter pasteurianus
           RepID=C7JHE3_ACEP3
          Length = 329

 Score =  223 bits (570), Expect = 5e-57,   Method: Composition-based stats.
 Identities = 57/309 (18%), Positives = 103/309 (33%), Gaps = 15/309 (4%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGK 74
            I   F        L  ++D A         EG  L  + D  V +  F P      IG+
Sbjct: 18  FIRQHFSALAGAAALELRDDAAVF----TPPEGRELVIAADGMVENVHFLPDDPPETIGR 73

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
             +    +D+A  G+ P      F     +  + +      +       G+ ++ GDT  
Sbjct: 74  KLLRCNLSDLAAMGSRPEGWLLTFARPPHITEQWVAQFCKGLKADQAQFGLQLLGGDTTS 133

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
            +      L ++   +G++        Q   AGD L V+GT+GD    +  L+ ++    
Sbjct: 134 TRG----PLVLSLTILGSVLPGQAIRRQGAQAGDGLWVTGTIGDGALGLRALQGEIADPS 189

Query: 195 ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
             ++    L      L       A  D +  G+       A      + +   A+P+  A
Sbjct: 190 GYLAQRYRLPQPRIGLPLYGLASAAMDISD-GLLQDAGHLARESELHVTIHADAVPLSDA 248

Query: 255 VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLA--ALHSHPLGKDAALIGEVVERK-G 311
            R          L   ++ +++ AV       +L+   L +         IGE  +   G
Sbjct: 249 ARQTGPKWLETCLTGGDDYEILFAVPAQHEAALLSKGTLDTVCGPVKVTRIGEFTQASTG 308

Query: 312 VRLAGLYGV 320
           V +    G 
Sbjct: 309 VTVLDSAGK 317


>UniRef50_Q0ABQ2 Thiamine-monophosphate kinase n=3 Tax=Gammaproteobacteria
           RepID=Q0ABQ2_ALHEH
          Length = 321

 Score =  223 bits (569), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 84/324 (25%), Positives = 116/324 (35%), Gaps = 28/324 (8%)

Query: 17  QLINSLFME--AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGN 71
           QLI S F          L   +D A L  A     G  L    D+ V    F    P   
Sbjct: 5   QLIRSYFQPDARGEGVVLGVGDDAALLQPA----PGQLLVTCVDTLVAGVHFPEDAPPDA 60

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  A+    +D+A  GA PR+      L E +    L A  + +   A    +A+V GD
Sbjct: 61  VGHKALAVNLSDLAAMGARPRWFQLALTLPE-IDEAWLAAFSSGLHRLAAEQDVALVGGD 119

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL- 190
           T          L I    MG +            AGD L V+GTLGD    +   +  + 
Sbjct: 120 TTRGP------LTITVQAMGEVAPAQALRRTGARAGDRLYVTGTLGDAAQGLALWQRGVR 173

Query: 191 -----GLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAAC-GCGIEL 244
                   G L+      TP +   R   G+         G+ A +        G G  L
Sbjct: 174 SAGGDDPAGFLIDRLHRPTPRMAAGRAAAGLARAAIDISDGLLADLGHLLEGGEGLGAVL 233

Query: 245 SEAALPVKPAVRGVCE--LLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
              +LP+ PA R  CE  L G  AL+  ++ +L+ AV          AL   P G     
Sbjct: 234 QADSLPLSPAYRAHCEDSLPGRAALSGGDDYELLFAVAPENEAAFQTALQHVPAG--CTC 291

Query: 303 IGEVVERKGVRLAGLYGVKRTLDL 326
           IG + E   + L G  G  + L  
Sbjct: 292 IGWITEDSAITLQG-DGKAQVLTR 314


>UniRef50_C3N301 AIR synthase related protein domain protein n=9 Tax=Sulfolobus
           RepID=C3N301_SULIA
          Length = 402

 Score =  223 bits (569), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 75/336 (22%), Positives = 129/336 (38%), Gaps = 20/336 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAE-QEDQARLDLAQLVAEGDR-LAFSTDSYVIDPLFFPG 69
           G+  + L N +                Q  +D A +  +  R L   TD   I P F   
Sbjct: 65  GKINEDLFNKVIYPHLGEKRTEVLVGPQHGVDTAAIDLQDGRILVVKTDPVFIVPQFG-F 123

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
                 A+   A+DV  SG  P+Y      L   +  +  + +   + E  +   + +V 
Sbjct: 124 KKAAWFAVHILASDVMTSGIPPQYAVIDVNLPPKIKDDEFEEMWIGIHEALKEIEVMVVG 183

Query: 130 GDTKVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
           G T V +    D   +      G            +  GD ++++         +L    
Sbjct: 184 GHTGVYE--GTDYPMVGGFTMFGIGEKEKLGMPSKVRVGDSVIMTKGPAIEATGLLTNLY 241

Query: 189 ----QLGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACG 239
               +  LD E  ++   +   +   +D       G+  + DAT GGV   + E A A G
Sbjct: 242 PEYFKQRLDKETFNEAYNIYWKMSCWKDGLIASRIGIHLMHDATEGGVFGALTEVARASG 301

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            G+ + E  L +  AVR V  L+ +D     +EG ++I  ++     V  AL     G +
Sbjct: 302 KGMNVYEDKLFINSAVREVTRLVNIDPWISISEGTMIIVTDKGK--DVREALIKE--GIE 357

Query: 300 AALIGEVVERKG-VRLAGLYGVKRTLDLPHAEPLPR 334
           A +IGE+V++ G V+L    G +  ++ P  +P  R
Sbjct: 358 AEIIGEIVDQSGDVKLVKKDGSRVKIEHPLEDPFWR 393


>UniRef50_Q9V1N8 Probable thiamine-monophosphate kinase n=3 Tax=Pyrococcus
           RepID=THIL_PYRAB
          Length = 310

 Score =  223 bits (569), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 61/318 (19%), Positives = 112/318 (35%), Gaps = 29/318 (9%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV---IDPLFFPGGNIGKL 75
           I SLFM+ F    L         D   +      L  ++D  V     P F    + G+ 
Sbjct: 10  IISLFMKHFERHSLG-------DDAGFIKLNNSWLLVTSDMLVWKTDVPDFMTPEDAGRK 62

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVV 135
            +    +D+A  G  P        +   +  + L+ +   + E ++   + IV+GDT   
Sbjct: 63  VVTMNVSDIAAMGGRPMAFFFSLAVPGDVSEDILRGIARGINEGSKVYKLKIVSGDTN-- 120

Query: 136 QRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE 195
                D + I+   +G               GD++ V+G LG     +L       +  E
Sbjct: 121 ---EADDIIIDGGSLGI--GKRLLLRSNAKPGDLVCVTGDLGRPLTALLLWMRGEKIPRE 175

Query: 196 LVSDCAVLTPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
           +          ++  ++      +  D +  G++  + E A A    I + E  LP+  +
Sbjct: 176 IEEKARNPRARVEEGVKLSSLANSAIDISD-GLSKELWEIANASNVRIIIEEERLPISDS 234

Query: 255 VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
           V+ +       AL    E +L+  + R   E++           D  +IG V    GV +
Sbjct: 235 VKEIVSDPVKVALASGEEFELLFTIPREKVEEL---------DIDFKIIGRVEGGNGVYI 285

Query: 315 AGLYGVKRTLDLPHAEPL 332
                    L++   E L
Sbjct: 286 K-RGRKIEELEVLGWEHL 302


>UniRef50_B8GHF5 AIR synthase related protein domain protein n=1
           Tax=Methanosphaerula palustris E1-9c RepID=B8GHF5_METPE
          Length = 345

 Score =  223 bits (568), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 73/336 (21%), Positives = 131/336 (38%), Gaps = 28/336 (8%)

Query: 19  INSLFMEAFANPWLAEQEDQ------ARLDLAQLVAEGDRLAFSTDSYVIDPLFF----P 68
           I++    +F        +        A +D   +    +R+         DP+F     P
Sbjct: 9   IDAATFASFLLHRTGAADPSVIVPPTAGIDAGVVDLGNNRVLI----VAEDPIFAIPNQP 64

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
               G   +   A+DVAV G  P+Y++   ++  G P +  + +V ++   A+  GIAIV
Sbjct: 65  YDLFGWHTVHIGASDVAVMGVKPQYMTYSLLMPPGTPDQDFRTIVDAIDLAAKDLGIAIV 124

Query: 129 TGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
            G T      A   +              +  +     GD +L++       A +L++  
Sbjct: 125 GGHTGYYPGFAAPTIG-GITVFAVAEKGEYITSAGARPGDDVLLTKGPAIETAALLSVLR 183

Query: 189 QLGLDGELVSDCA----------VLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAAC 238
           +  L  +  +              +       R+   V A+ DAT GGV   + E AAA 
Sbjct: 184 ENELKAKYPAWLVKAAQDLCWQMSVVADAALAREAGEVTAMHDATEGGVIGGLFEIAAAS 243

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             G+ + EA +     VR VCE   LD L    EG L++  + ++++ ++  L     G 
Sbjct: 244 NTGMVIDEAQIIYPKEVRMVCEQFNLDPLASIAEGTLLLTADPSSSDAIIDLLTR--SGI 301

Query: 299 DAALIGEVVERKG-VRLAGLYGVKRTLDLPHAEPLP 333
             ++IG+V +  G   +  + G    L +P  +P  
Sbjct: 302 PVSVIGKVTDNPGERTIRRVDGTIEELHIPEQDPFW 337


>UniRef50_D1BMW6 Thiamine-monophosphate kinase n=3 Tax=Veillonella
           RepID=D1BMW6_VEIPT
          Length = 326

 Score =  222 bits (567), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 57/320 (17%), Positives = 108/320 (33%), Gaps = 26/320 (8%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLF----FPGGNI 72
            I  +      NP           D A    E       STD+ V    F        ++
Sbjct: 11  FIRQIQNNTIYNPNTVVY--GIGDDCAIYKTEQNTEQLISTDTMVEGIHFSFHYMTPYDV 68

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G   +    +DVA  G IPR +     + + +    L  +   + +      + I+ GDT
Sbjct: 69  GYRLMTANLSDVAAMGGIPRQIVLSLAVSDHIDTAILDEIYRGIKDQCMRYQLNILGGDT 128

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
              +      +      +G IP            GDV+ ++  +G     +  L   L  
Sbjct: 129 VRTEG----PMVWTVTIIGEIPKGTAVMRSGAKVGDVVGLTNYVGYAATGLGALSYNLVG 184

Query: 193 DGELVSDCAVLTPLIQTLRDIP--GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
                       P I+  + +   G+ ++ D +  G+ + ++E A A    I   E A+P
Sbjct: 185 YDMTKVGHQRPEPQIELGQKLRLLGIHSMNDISD-GLGSELNEIAVASNVSIVFEEQAIP 243

Query: 251 VKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           +      + + L  +     L    + +LV    ++   ++              LIGEV
Sbjct: 244 LHEETYELAKHLQTNPVDYALYGGEDFQLVFTAPKSLLSELEKL-------AGITLIGEV 296

Query: 307 VER-KGVRLAGLYGVKRTLD 325
           +     V++  L    +T++
Sbjct: 297 LSGPPRVQMVTLDKTIKTIE 316


>UniRef50_A1AS86 Thiamine-monophosphate kinase n=9 Tax=Desulfuromonadales
           RepID=A1AS86_PELPD
          Length = 333

 Score =  222 bits (567), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 71/322 (22%), Positives = 117/322 (36%), Gaps = 24/322 (7%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQ-LVAEGDRLAFSTDSYVIDPLFFPGGN----I 72
           LI+ +         +         D A  ++  G +L  STD  + D  F    +    +
Sbjct: 15  LIDRIAAHVAGGEGVITG---IGDDAAVTVLTPGMQLLTSTDMLLEDVHFRTTWHDPLAL 71

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ ++  + +DVA  GAIPR+      +  G P+E L          A   G+ ++ GDT
Sbjct: 72  GRKSLGVSISDVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAGEHGVTLIGGDT 131

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-G 191
              + G    L I+   M     ++        AGD + VSGTLGD    +  L +    
Sbjct: 132 CSSKNG----LVISVTIMAEQFPHLILRRSGARAGDEIWVSGTLGDAALVLSLLEDGAVC 187

Query: 192 LDGELVSDCAVLTPLIQ---TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
            +  L+S     +P  +    L +   V A+ D +  G+ A     A   G G  L    
Sbjct: 188 DEPSLLSRLLDPSPRTRVGHALAESGLVSAMIDVSD-GLLADFGHIAQQSGVGGVLYLER 246

Query: 249 LPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           LP+    R              L+   + +L         E++ + +     G  A  +G
Sbjct: 247 LPISADFRRRASRFPSFPHHLILSGGEDYELAFTAAAENHEKIESIVK--NSGIQATAVG 304

Query: 305 EVVERKGVRLAGLYGVKRTLDL 326
            V    GV +    G  R +  
Sbjct: 305 IVTSFSGVEVVMEDGS-RYIPR 325


>UniRef50_Q0W120 Putative thiamine monophosphate kinase n=2 Tax=Euryarchaeota
           RepID=Q0W120_UNCMA
          Length = 322

 Score =  222 bits (567), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 76/319 (23%), Positives = 116/319 (36%), Gaps = 36/319 (11%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV---IDPLFFPGGNIGK 74
           LI     +   +P+L         D A +    D L  +TD        P    G +IG 
Sbjct: 11  LIRR-IGKILQSPYLG-------DDCAVIDNGNDYLVVTTDMLHRVTDFPREMTGEDIGW 62

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
           +++  + +DVA  GA P  +     +     +E +  + T M   A+  G  I+ GDT  
Sbjct: 63  MSVAVSLSDVAGMGARPVGVVAAIGIPGDTDIEFIDGIATGMRNCAKCYGTDIIGGDTDQ 122

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
                  +L I T   G +  +          GD+L V+G LG   A    L  +     
Sbjct: 123 H-----QELTIVTTAFGRVNKDQVKLRSGAKVGDLLCVTGYLGTTAAGFKVLTGEREASP 177

Query: 195 E----LVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           E    L        P +     L   PGV A+ D +  G+   V+E + A   G  +   
Sbjct: 178 EDRQILFRSFFRPEPRLGEGMILAQYPGVTAMMDVSD-GLGKSVYELSVASKVGFIVYAD 236

Query: 248 ALPVKPAVRGVCE---LLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           ALPV+   R V      L   A+ F  E +L+  V  +    +         G D  +IG
Sbjct: 237 ALPVREEARKVARSRTELLDMAICFGGEFELLFTVNPDEVGNIK--------GVDFTVIG 288

Query: 305 EVVERKGVRLAGLYGVKRT 323
           +V E  G+ L         
Sbjct: 289 KVTE-SGLVLDDRGARTEI 306


>UniRef50_Q6AKX6 Related to thiamine-monophosphate kinase (ThiL) n=1
           Tax=Desulfotalea psychrophila RepID=Q6AKX6_DESPS
          Length = 328

 Score =  222 bits (567), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 62/301 (20%), Positives = 102/301 (33%), Gaps = 28/301 (9%)

Query: 38  QARLDLAQLVAEGDR-LAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPR 92
               D A    +  R    +TD+ V    F     P   +G  A+    +D+A  G +P 
Sbjct: 24  GIGDDCAVFSGDNGRPWLITTDTLVEGHHFDLSWHPAYELGCKAMAVNISDIAAMGGLPV 83

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
           + +      +      L   +  +A       I ++ GDT      A ++L I    +G 
Sbjct: 84  HATISLTFTKDTEEAWLDEFIRGLAYMHHRYNINLIGGDTV-----AGERLSITVTLLGQ 138

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVL--------- 203
                         GD++ V G LG   A +   +        L  + A L         
Sbjct: 139 AHKE-PVYRHGAMPGDIIYVGGPLGSAAAGLFLFQNHRDEIETLKDEYASLLRHHLAPMP 197

Query: 204 -TPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELL 262
              L + L D   + A++D +  G+   +   A        + E  +PV P    +C+  
Sbjct: 198 QVELGRALADSDYIGAMQDISD-GLATDLAHIAKKSAVQAVVFEDKIPVLPEFTRLCKRY 256

Query: 263 GL----DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLY 318
            L     AL   ++  L+  V     ++V     S      A  IG + E  GV L G  
Sbjct: 257 QLTATELALGGGDDYLLLFTVRAGREKEVERLARSVQA--MAYPIGLITEGSGVMLKGPT 314

Query: 319 G 319
           G
Sbjct: 315 G 315


>UniRef50_C0GCU5 Thiamine-monophosphate kinase n=1 Tax=Dethiobacter alkaliphilus AHT
           1 RepID=C0GCU5_9FIRM
          Length = 335

 Score =  222 bits (566), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 71/326 (21%), Positives = 115/326 (35%), Gaps = 24/326 (7%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFST-DSYVIDPLF----FPGG 70
           + LI     E       A        D A      +    ++ D  V    F        
Sbjct: 9   RALIKQ-ITEVLGESASANGFVGIGDDAALTTCNKEAWLVTSKDMLVEGVHFLLPAMTPA 67

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A+    +D+A  G +PR+      L +   +E +      M   A   G  I  G
Sbjct: 68  DLGYKALAVNISDIAAMGGVPRHAYVALALPKETGVEFILEFYRGMGPLAAELGTTISGG 127

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ- 189
           DT          L I+    G +           + GD+L  +G LG   A +  L  + 
Sbjct: 128 DTVSSPG----PLMISITVQGEVDRQKALLRSGASPGDILCTTGPLGASAAGLALLLNRE 183

Query: 190 ----LGLDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
                 L  + ++      P ++    L     V A  D +  G+   + E + A GCG+
Sbjct: 184 LDCPEKLRSQALNAHFRPVPRVREADFLAHSGAVTAAMDISD-GLLEDLGEISQASGCGV 242

Query: 243 ELSEAALPVKPAVRGVCELLG----LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
            L E  +PV PA + +  L        ALN   + +L++AV+      +     S   G 
Sbjct: 243 LLEEDKIPVHPAAQQIAPLAQSLAAEWALNGGEDYELLLAVQSRRFASLSREYESR-FGV 301

Query: 299 DAALIGEVVERKGVRLAGLYGVKRTL 324
               IG+VV  KG+ +    G +  L
Sbjct: 302 PLMPIGKVVGEKGLWMVTKEGKRVKL 327


>UniRef50_B8D020 AIR synthase related protein domain protein n=1 Tax=Halothermothrix
           orenii H 168 RepID=B8D020_HALOH
          Length = 348

 Score =  222 bits (566), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 69/333 (20%), Positives = 124/333 (37%), Gaps = 23/333 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQE-DQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+  +  + SL +                  D A +    + L  S+D     P+     
Sbjct: 4   GKIPKNKLESLIINKIKYHHKDVLVHSGIGEDSAVVDFGDEVLVISSD-----PITGAVN 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
             G LA+    ND+A  GA P  +    +L        +  ++  +   A +  + ++ G
Sbjct: 59  KAGYLAVHVACNDLASCGARPVGIQVVLLLPPATEEIMVGNIMEEITRAAASIEVEVIGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN----- 185
            T+++ +  V +  I    +G  P + +        GD L+++  LG  G  IL      
Sbjct: 119 HTEILSK--VTEPIITVTAIGKAPRDKYITTGGARPGDELIITKGLGIEGTFILASDYAE 176

Query: 186 LREQLGLDGELVSDCAVLTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAACGC 240
           L +  G+  E++         +  L +       GV A+ D T GG+   + E   A   
Sbjct: 177 LLKDRGVPPEIIERGQEYISKLSVLEEGLIGAGLGVHAMHDITEGGLYGALDEMVTASKA 236

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           G  +  +  PV P    +C+ L LD     + G ++IA       +++  L     G  A
Sbjct: 237 GFRIKRSQFPVNPETDIICKALDLDPAGLISSGSMLIAAP--DGGKLVDKLARA--GIKA 292

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
           ++IGE+ E  G  +    G    L     + L 
Sbjct: 293 SIIGEITEE-GCLIEDENGEFEELSGEIKDELW 324


>UniRef50_Q3AE31 Thiamine-monophosphate kinase n=1 Tax=Carboxydothermus
           hydrogenoformans Z-2901 RepID=Q3AE31_CARHZ
          Length = 326

 Score =  222 bits (566), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 61/305 (20%), Positives = 109/305 (35%), Gaps = 26/305 (8%)

Query: 34  EQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVSGA 89
                   D A +  +G  L  +TD  V +  F         +GK A+    +D+A  G 
Sbjct: 24  GVILGIGDDAAVVEIKGK-LLVTTDLLVENVHFKRNYTKPEILGKKALAVNLSDIAAMGG 82

Query: 90  IPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAG 149
           IPR+      L +   +  ++     +   A+  G+ ++ GDT     GA  ++ +    
Sbjct: 83  IPRFCLVSLALPKTTEVNFVEGFYQGLKSMAKEYGVTLIGGDTT----GAGSEIMVAVTV 138

Query: 150 MGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ------LGLDGELVSDCAVL 203
           +G               GD + VSG LGD  A +  L ++        ++  L+S     
Sbjct: 139 LGEALEEGVLTRSGAKPGDGVYVSGYLGDSAAGLYLLLKEKLGLLPEEVEKYLISRHLEP 198

Query: 204 TPLIQ---TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCE 260
            P ++    L       +  D +  G+   + E A A G  I ++   +P+  A+   C+
Sbjct: 199 EPRLELGQLLCREKFATSTNDLSD-GLVKKLQEIARASGVEITINREKIPLSFALLTFCQ 257

Query: 261 LLGLDA----LNFANEGKLVIAVERNAAEQVLAA---LHSHPLGKDAALIGEVVERKGVR 313
              L      L+   + +L+  V     E++      L    +       G V    GV 
Sbjct: 258 QFTLKPLDFALHGGEDYELLFTVPAEKEEELFKLDLPLFKIGMVTGYDERGRVKAEDGVV 317

Query: 314 LAGLY 318
           L    
Sbjct: 318 LQDRG 322


>UniRef50_C6X363 Thiamine-monophosphate kinase n=6 Tax=Bacteroidetes
           RepID=C6X363_FLAB3
          Length = 364

 Score =  221 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 63/333 (18%), Positives = 116/333 (34%), Gaps = 41/333 (12%)

Query: 18  LINSLFMEA-FANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNI 72
           LI  L  +  F NP           D A +  +  ++  +TD       F     P  ++
Sbjct: 34  LIKHLTEKFGFDNPSTET---SIGDDAAVIDPQNQKVVITTDILAEGVHFNLGYVPLKHL 90

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A   AIP  +  G  +    P+E L+ +   +A   +   + +V GDT
Sbjct: 91  GYKAVVVNLSDLAAMNAIPTQILVGLAVSNRFPVEALEEIYEGIALACKRYKVDLVGGDT 150

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ--- 189
                G    L +    +G   +            D+L+V+G LG     +  L  +   
Sbjct: 151 TSSTSG----LVMGITAIGLEQSENLIKRSGAKPNDLLVVTGDLGGAYLGLQILEREHSV 206

Query: 190 -----------LGLDGELVSDCAV--LTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFA 235
                       G D  L         T + +TL+++     ++ D +  G+++ +   A
Sbjct: 207 YLANPNMQPEMEGYDYILERQLKPEARTDIKKTLKELDIQPTSMIDVSD-GLSSEILHLA 265

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAAL 291
                G  L E  +P+        E L L+     +N   + +L+  +     E++    
Sbjct: 266 DQSKVGFRLYEEKIPMDSLTISTAEELNLNPVMCAMNGGEDFELLFTIAPEDFEKIRN-- 323

Query: 292 HSHPLGKDAALIGEVVERKGVRLAGLYGVKRTL 324
                  D ++IG  VE          G    +
Sbjct: 324 -----HPDFSIIGHAVEADEGNFLVARGSNELI 351


>UniRef50_C6VU01 Thiamine-monophosphate kinase n=25 Tax=Bacteria RepID=C6VU01_DYAFD
          Length = 340

 Score =  221 bits (564), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 60/331 (18%), Positives = 113/331 (34%), Gaps = 39/331 (11%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIG 73
           LI  +       P L +       D A +    +    ++D ++    F    FP  ++G
Sbjct: 15  LIQRI--NKGIRPALPDTVRGIGDDAAVIDLGEELGLLTSDMFLEGIHFDLTFFPLKHLG 72

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
              I    +D+A    IPR ++    L     +E +  +   M    +   + +V GDT 
Sbjct: 73  YKIIAAGVSDIAAMNGIPRQVTVNLALSNRFSVEAVDELYEGMKVACKDFNVDLVGGDTT 132

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE----- 188
             + G    L I+ +  G +  +      T    D+L V+G LG     +  L       
Sbjct: 133 SSRSG----LIISVSAFGKVKKDKIAYRNTAQPNDLLCVTGDLGGAYMGLQLLEREKQVF 188

Query: 189 --------QLGLDGELVSDCAVLTPLIQTLRDIPGV----KALRDATRGGVNAVVHEFAA 236
                   +L     ++         +  + ++        ++ D +  G+ + +    A
Sbjct: 189 LANPNMQPELEGKDYVIQRQLRPEARMDVVYELDEAGVIPTSMIDLSD-GLASDLLHICA 247

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGL----DALNFANEGKLVIAVERNAAEQVLAALH 292
             G G  + E  LP+          L +     ALN   + +L+  V ++A EQ+     
Sbjct: 248 QSGVGAVIFEERLPIDEQTYLAASELNIGAATAALNGGEDYELLFTVSQSAYEQIKN--- 304

Query: 293 SHPLGKDAALIGEVVERKGVRLAGLYGVKRT 323
                     IG + ++KG       G  R 
Sbjct: 305 ----NPKITFIGYITDKKGEVELHTKGDTRV 331


>UniRef50_D1R9A7 Putative uncharacterized protein n=1 Tax=Parachlamydia
           acanthamoebae str. Hall's coccus RepID=D1R9A7_9CHLA
          Length = 333

 Score =  221 bits (564), Expect = 3e-56,   Method: Composition-based stats.
 Identities = 65/331 (19%), Positives = 123/331 (37%), Gaps = 25/331 (7%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGD-RLAFSTDSYVIDPLFF----PGGNIG 73
           I       F+             D A + AE +     +TD+ +    F        ++G
Sbjct: 11  IIHYLSHCFSAKN---GIVGIGDDCAVIPAENEEAWLVTTDALIEGVHFLKDQIAPIDLG 67

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
              I    +DVA  G  P++      L   +  E  + V+  + E      I ++ GDT 
Sbjct: 68  YKTIAVNVSDVAAMGGTPKFAFLTLALPSTVHCEWTRLVLQGIKEACEKWHIQLLGGDTV 127

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
               G+   +FIN   +G+ P            GD + VSG LG+ G  +  L+E++   
Sbjct: 128 ----GSRRDIFINLTLIGSAPQKHIRYRNQAQLGDRICVSGNLGNSGGGLQALKEKIQTT 183

Query: 194 GE---LVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
            E   L+      TP I   + L   PGV A+ D +  G++  +     +   G  +  +
Sbjct: 184 PEVKILLEAHFRPTPHIQQGRWLASQPGVHAMMDVSD-GLDFDLKRLIKSSHKGAHVDIS 242

Query: 248 ALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
            +P+   +  + +  G +     L    +  L+I +++     +         G     I
Sbjct: 243 KIPLSEELLKMAQTKGWNPLQLALTGGEDYCLLITIDQKKQGVIQDFFKK--FGAPLYEI 300

Query: 304 GEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           G++ ++        +G K+ +D P  +   +
Sbjct: 301 GQITDQVNELTYYDHGEKKEIDFPPFDHFHK 331


>UniRef50_Q8ESJ0 Thiamine monophosphate kinase n=1 Tax=Oceanobacillus iheyensis
           RepID=Q8ESJ0_OCEIH
          Length = 322

 Score =  220 bits (561), Expect = 6e-56,   Method: Composition-based stats.
 Identities = 65/320 (20%), Positives = 115/320 (35%), Gaps = 24/320 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNI 72
             I+S+    +  P L +       D A +      +  + D++V D  F        +I
Sbjct: 5   SFIDSIKPTYYRQPSLLKG----IGDDAAVFRSSKDIVTAVDTFVEDVHFSRSTMEPYHI 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P +     ++ +      L  + + M + A    + I+ GDT
Sbjct: 61  GYRALGANISDLAAMGASPSFYLVSIVIPKNWTQAELSQIYSGMDDLASKYHMDIIGGDT 120

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL----RE 188
                    +L I+   +G    N     Q    GD++ V+GTLGD  A    L      
Sbjct: 121 VS-----GKQLTISITVIGYTITNKARYRQHAKEGDIVFVTGTLGDSLAGFHILTSDNEN 175

Query: 189 QLGLDGEL-VSDCAVLTPLIQTLRDIPGV--KALRDATRGGVNAVVHEFAAACGCGIELS 245
              +D +  +       P +   + +  +   +L D +  G+     E A A    I L 
Sbjct: 176 NRYVDQDFYIHRHRKPEPRVAFAQALESLDRVSLNDVSD-GIANEASEIAEASNVSIVLR 234

Query: 246 EAALPVKPAVRGVCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           E  +PV P+             L+   + +L+  V +     V  A  +        +IG
Sbjct: 235 ENDIPVAPSFYQFTYEQQYQWKLSGGEDFELLGTVAKGDWAVVNEA--AEKTNTQLTVIG 292

Query: 305 EVVERKGVRLAGLYGVKRTL 324
            VVE +   +       R +
Sbjct: 293 SVVEEEKHPVYIEDNAMRKV 312


>UniRef50_A6CFS7 Thiamine-monophosphate kinase n=1 Tax=Planctomyces maris DSM 8797
           RepID=A6CFS7_9PLAN
          Length = 307

 Score =  220 bits (561), Expect = 7e-56,   Method: Composition-based stats.
 Identities = 59/317 (18%), Positives = 104/317 (32%), Gaps = 33/317 (10%)

Query: 17  QLINSLFMEAFAN--PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGG 70
           +LI  +  +   +    L   +D A L           L  +TD  +    F        
Sbjct: 8   ELIEWIRSQKGMSHTNLLGIGDDTAILQ----PPAHSELLLATDMLMEGAHFTFPPATPE 63

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
             G+ A+    +D+A  G  P        L      E  K+V+  + E A      +  G
Sbjct: 64  LAGRKALAVNLSDIAAMGGSPHSALVSLALPRSRGSEFAKSVMQGIMELAAEFQTQLAGG 123

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          L IN A +G    +          GD + V+G LG            L
Sbjct: 124 DTNSWNG----PLVINVAIIGTADQSHSIKRSGAQPGDWIFVTGALGGS-----LESHHL 174

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
                +    A        L +   +K++ D +  G+ + +         G  +    +P
Sbjct: 175 TFQPRVREAVA--------LMETVTIKSMIDVSD-GLASDLQHILVESDVGAVIQSKQIP 225

Query: 251 VKPAV-RGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE 308
           + P V   + +   L  AL+   + +L+  V     +++      +PL      IG++  
Sbjct: 226 ISPRVSSELTDAERLQKALSDGEDFELLFTVSAEQGQRLRD---QNPLSIPLTHIGKITA 282

Query: 309 RKGVRLAGLYGVKRTLD 325
            +G  L    G    L+
Sbjct: 283 EQGALLQQTDGSTTPLE 299


>UniRef50_B0TDV9 Thiamine-monophosphate kinase n=1 Tax=Heliobacterium modesticaldum
           Ice1 RepID=B0TDV9_HELMI
          Length = 373

 Score =  220 bits (560), Expect = 7e-56,   Method: Composition-based stats.
 Identities = 70/309 (22%), Positives = 113/309 (36%), Gaps = 42/309 (13%)

Query: 31  WLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAV 86
            L   +D A +D    V  G  L  +TD  V    F         +G+ A+    +D+A 
Sbjct: 49  RLGIGDDAAVID----VPGGKPLLVTTDMLVEGVHFLWSPIRRRLLGRKALAVNISDIAA 104

Query: 87  SGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFIN 146
            G IP +      +     +E ++ +   M E A   G+ +  GDT        DK  IN
Sbjct: 105 MGGIPAWAFLSIGVPASAKVEEVEGLYAGMGEMAAQFGVELAGGDTVRS-----DKWVIN 159

Query: 147 TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCA----- 201
              +G        G      GD++LV+GT+GD  A +  L  +  +      D       
Sbjct: 160 VTLLGLAVK-APIGRSGGRPGDLILVTGTVGDAAAGLHLLLMETKMSQAEKMDAQMREAP 218

Query: 202 -----------------VLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
                                  + L D  GV A+ D +  GV++ VH      GCG  +
Sbjct: 219 IGEADRQALLLRHLDPIPRVAEARALVDYGGVTAMMDVSD-GVSSEVHHLCRNSGCGARI 277

Query: 245 SEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
             A LP+ PAVR +    G +    AL+   + +L+          ++  +     G   
Sbjct: 278 DLANLPISPAVRRLARREGREVFAWALSGGEDYELIFTAPEERVPGLIDHVRRET-GTGV 336

Query: 301 ALIGEVVER 309
            +IG + + 
Sbjct: 337 TVIGRLTDG 345


>UniRef50_B3QYZ8 Thiamine-monophosphate kinase n=1 Tax=Chloroherpeton thalassium
           ATCC 35110 RepID=B3QYZ8_CHLT3
          Length = 373

 Score =  220 bits (560), Expect = 8e-56,   Method: Composition-based stats.
 Identities = 67/322 (20%), Positives = 116/322 (36%), Gaps = 47/322 (14%)

Query: 38  QARLDLAQLVAEG-DRLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPR 92
               D A L     +    +TD  +    F     P  ++G  AI    +D+    A+P 
Sbjct: 35  GIGDDCAILEFSDTEYQVVTTDLLIEQIHFDLLTTPMEHLGAKAISVNVSDICAMNALPT 94

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
           Y      L E L +E ++++   M+  A+  G+AIV GDT     G    L I+   +G 
Sbjct: 95  YAVVSIALSEKLSVEMVESLYKGMSNAAKEYGLAIVGGDTSASTAG----LVISVTIVGK 150

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL-------------------- 192
           +         T   GDV+ VSG LG   A +  L  +  L                    
Sbjct: 151 VKKEKVARRSTAKPGDVVCVSGVLGGSHAGLKVLMRERKLMLDNLKEDGSVDENYRPEIA 210

Query: 193 -DGELVSDCAVLTPLIQTLR--DIPGV--KALRDATRGGVNAVVHEFAAACGCGIELSEA 247
              + VS   +    +  +R  +  G+   A+ D +  G+ + +         G  + E 
Sbjct: 211 DYQDAVSRHLLPKARLDIVRLFERRGIVPTAMIDISD-GLASEIKHICKESKTGAIIEEN 269

Query: 248 ALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
             P+    R V +    +    AL    + +L+  +    AE++           D  +I
Sbjct: 270 KFPIMSHARHVADEFEEEATTYALYGGEDYELLFTLSPEDAEKLQET-------DDVKII 322

Query: 304 GEVVERK-GVRLAGLYGVKRTL 324
           GE+     GV +  ++  +  L
Sbjct: 323 GEIKPEAYGVVMLDMFAREIDL 344


>UniRef50_B0MTR2 Putative uncharacterized protein n=1 Tax=Alistipes putredinis DSM
           17216 RepID=B0MTR2_9BACT
          Length = 310

 Score =  220 bits (560), Expect = 9e-56,   Method: Composition-based stats.
 Identities = 58/300 (19%), Positives = 104/300 (34%), Gaps = 28/300 (9%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFF----PGGNIG 73
           I  +F     N       D    D        G+ L F+ D    +  F         +G
Sbjct: 10  IRDMFAAIPRN-----GFDGIGDDCTVFPLGSGESLVFTADLLAENIHFLRRATSARELG 64

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
           + ++    +DVA  GA P        +   LP   ++  +    + +    + +V GDT 
Sbjct: 65  RKSLAVNLSDVAAMGARPIATLLSLAIPHDLPEGWIEDFMEGYRDLSAQYDVGLVGGDTT 124

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
               G    L +N   +G I  +          GD++ V G+LG+ GA + ++      D
Sbjct: 125 ASDSG----LVVNVTAIGRIADSHIKRRSDARPGDLIAVGGSLGESGAGLRDILAGR-YD 179

Query: 194 GELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
             L        P +     L + P V A+ D +  G+ + +       G G E+    +P
Sbjct: 180 TPLAQIHRNPAPQVAEGIWLGERPEVHAMMDISD-GIASDLRHILHQSGVGAEVDTECIP 238

Query: 251 VKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
               +          A++   + KL+  V   +A  +L+       G +   IG +    
Sbjct: 239 TPVDL--------ETAVSGGEDYKLLFTVAPESANTLLSNYR-LRFGDEFHFIGRITGGN 289


>UniRef50_B9KXI5 Thiamine-monophosphate kinase n=1 Tax=Thermomicrobium roseum DSM
           5159 RepID=B9KXI5_THERP
          Length = 341

 Score =  219 bits (559), Expect = 9e-56,   Method: Composition-based stats.
 Identities = 67/330 (20%), Positives = 116/330 (35%), Gaps = 25/330 (7%)

Query: 11  GGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---- 66
           G + + + I  L  +      +   +D A    A     G  L  +TD+ +    F    
Sbjct: 12  GEEELIEQIARLVGDRSNRVSIGIGDDAA----AWRPRAGHELVITTDTLIERVHFRLEW 67

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
                +G  ++    +D+A  GAIPR       +        +      +   AR  G+A
Sbjct: 68  TDWEALGHKSLAVNLSDIAAMGAIPRLAVVDLAVRGTERDRDIADFYRGVQALARRFGVA 127

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPAN--IHWGAQTLTAGDVLLVSGTLGDHGATIL 184
           IV GDT     G    + ++   +G  P +            GD++ V+G +G   A + 
Sbjct: 128 IVGGDTTRSPLG----VAVSITVIGESPRDGHRLLRRDAGRPGDLIGVTGPIGLAAAGLR 183

Query: 185 NLREQ---LGLDGELVSDCAVLTPLIQT--LRDIPGVKALRDATRGGVNAVVHEFAAACG 239
            L      L  +  +        P ++   L    GV+A  D +  G+   + +   A G
Sbjct: 184 VLERGLKTLDGNPVMQEHYHRPQPRVREGLLLRRCGVRAAMDISD-GLLGDLQKLCRASG 242

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
               +    +PV  A++         AL   ++ +L+ A       +V  A     L   
Sbjct: 243 VAAIVDLERVPVPNAIKWAFPDWEEVALRGGDDYELLFAAPPAVFARVARAFARAGL-LP 301

Query: 300 AALIGEVVE----RKGVRLAGLYGVKRTLD 325
              IG++VE       V L  + G  R  D
Sbjct: 302 PWKIGQLVEAGSAGPIVELRDVTGRCRPAD 331


>UniRef50_Q1Q1A8 Similar to thiamine monophosphate kinase n=1 Tax=Candidatus
           Kuenenia stuttgartiensis RepID=Q1Q1A8_9BACT
          Length = 340

 Score =  219 bits (559), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 65/298 (21%), Positives = 103/298 (34%), Gaps = 29/298 (9%)

Query: 38  QARLDLAQLVAEGDRL-AFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPR 92
               D A +    + L   +TD  V    F         +G+ AI  + +D+A  G  P 
Sbjct: 57  GIGDDCAVINTAKNTLCLITTDMLVEGTHFDLKKHNASEVGRKAIACSISDIASMGCKPS 116

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
                     G      K +   + E A    I IV GD    +        IN   +G 
Sbjct: 117 VAVISLCFPHGTKNSFAKRLYAGIWEIADKYDIDIVGGDIISGEG----PFCINVTLLGK 172

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRD 212
               +        AGD +LV+G LG          + +  +  L    A        L  
Sbjct: 173 NEGLMPVYRSGAKAGDKILVTGRLGGSLLG-----KHMFFEPRLDEGIA--------LNK 219

Query: 213 IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA----LN 268
              V A+ D +  G+ A ++      G G  L E  +PV      + +  G        +
Sbjct: 220 NFTVHAMIDISD-GLTADLNHILEESGVGAVLFEDKIPVSDDALKISKKTGKTPIHHAFS 278

Query: 269 FANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDL 326
              + +L+  + +  AE+VL        G + + IGE+VE KG+ L    G  R +  
Sbjct: 279 DGEDYELLAVLSKTQAEKVLT--SDLFHGLEISCIGEIVEDKGLWLRDGKGKLRRIRP 334


>UniRef50_B4WXS9 Thiamine-monophosphate kinase n=1 Tax=Alcanivorax sp. DG881
           RepID=B4WXS9_9GAMM
          Length = 333

 Score =  219 bits (558), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 64/312 (20%), Positives = 106/312 (33%), Gaps = 30/312 (9%)

Query: 17  QLINSLFMEAFAN-PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNI 72
            LI   F     +   L   +D A L    +   G +L  + D+ ++D  F       ++
Sbjct: 34  SLIRRYFHHRQGDTVVLGPGDDGALL----VPPAGQQLVMTQDTSLVDRHFPADMAPADV 89

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G   +    +D+A  GA P +      L E +  + L      M E A  AGI++V GD 
Sbjct: 90  GYRCLAVNLSDLAAMGANPLWFLLSLTLPE-VDEDWLAEFSRGMFELADQAGISLVGGDI 148

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L ++    G++P  +         GD + + G  G     +   +     
Sbjct: 149 TRGP------LAVSIQATGSVPPGLALRRDGARVGDQICLGGVTGAGLLGLEQWQAGQRH 202

Query: 193 DGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAAC-GCGIELSEAALPV 251
              +             +       A  D +  GV A +     A  G G  L EAALP 
Sbjct: 203 GPAIGHFRRPRPQWELGMALRGQASACIDISD-GVLADLSHILQASGGLGACLDEAALPE 261

Query: 252 KPAVRGVCELLGLDA--LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
            P V   C      A  L   ++  L+  +             + P+ +    +G+V  +
Sbjct: 262 DPPVLAGCSADKQRALQLQGGDDYLLLFTLPA-----------AQPVPRGCYCLGQVDAQ 310

Query: 310 KGVRLAGLYGVK 321
            G+RL    G  
Sbjct: 311 PGIRLRQRNGAV 322


>UniRef50_A1SWW7 Thiamine-monophosphate kinase n=2 Tax=Psychromonas
           RepID=A1SWW7_PSYIN
          Length = 335

 Score =  219 bits (558), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 65/313 (20%), Positives = 111/313 (35%), Gaps = 33/313 (10%)

Query: 17  QLINSLFME----AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PG 69
            LI+S F        +   L   +D A LD    + EG +LA STDS V    FF     
Sbjct: 7   DLIDSYFKRSTTVQNSGVALGIGDDCALLD----IPEGYQLAVSTDSLVCGVHFFEDVDP 62

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGL----PMETLKAVVTSMAETARAAGI 125
             +G  A+    +D+A  GA+P+++S    L  G         L          A    +
Sbjct: 63  YRLGYKALAVNLSDLAAMGALPKWVSLAITLPNGAMVNNNPNWLSEFTRGFFALADKFDV 122

Query: 126 AIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN 185
            +V GDT          L I  +  G +P  +         GD++ VS  +GD    +  
Sbjct: 123 VLVGGDTTKGP------LSITVSVKGIVPRGLALQRNKANLGDLICVSNFIGDGALGLSI 176

Query: 186 LREQLGL--DGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGI 242
              +L +      V    +  P +     + G   +  D +  G+   +     A  C  
Sbjct: 177 KLNELAVTNPQYFVDALELTEPRVDLGILLRGLASSCIDISD-GLTQDLIHILKASHCAA 235

Query: 243 ELSEAALPVKPAVRGVCELLGLD-------ALNFANEGKLVIAVERNAAEQVLAALHSHP 295
            ++  +LP+   +R    L  L+       AL   ++ +L+  +  N    +   +    
Sbjct: 236 NIAIESLPLSKTMRKEVNLGKLNNDEAVQYALTGGDDYELLFTISENNLRLLEQRIAQQT 295

Query: 296 LGKD-AALIGEVV 307
                 ++IG   
Sbjct: 296 QPIPSLSVIGRTT 308


>UniRef50_B7JUY6 Thiamine-monophosphate kinase n=4 Tax=Cyanobacteria
           RepID=B7JUY6_CYAP8
          Length = 344

 Score =  219 bits (558), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 56/309 (18%), Positives = 108/309 (34%), Gaps = 33/309 (10%)

Query: 30  PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVA 85
           P     +D A L     V    +L  +TD  V    F     P   +G  A     +D+A
Sbjct: 25  PRDIIGDDGAILS----VDPAQKLVVTTDVLVDGVHFSDRTTPPATVGWRAAAANLSDLA 80

Query: 86  VSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI 145
             GA P  ++ G  L   +P+  ++ +   + +  +     IV GD           + +
Sbjct: 81  AMGANPIGITVGLALPGEVPVNWVETLYQGLNDCLQCYDTPIVGGDICRSP-----TITV 135

Query: 146 NTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ-------LGLDGELVS 198
           +    G +  +      +   G  ++V+GT G     +  L          +     L+ 
Sbjct: 136 SITAFGTVLPHRIIRRSSAQPGHAIVVTGTHGGSRGGLELLLNPQLGDHLTITEQQALIE 195

Query: 199 DCAVLTPLIQTLRDIPGV-----KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
                 P +  L  +  +      A  D +  G+   V +     G G ++  + + + P
Sbjct: 196 THQRPQPRLDVLPHLWEIVGTTEVAGMD-SSDGLGDAVVQICRMSGVGAKIERSQISLPP 254

Query: 254 AVRGV--CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG 311
           ++  +   E      L    + +LV+ +  + A+ ++  L     G  A +IGE+     
Sbjct: 255 SLLALVSPEQALQWGLYGGEDFELVLCLPFDLAKTLVERL-----GNGANIIGEITTEPR 309

Query: 312 VRLAGLYGV 320
           V L    G 
Sbjct: 310 VILIDSNGK 318


>UniRef50_Q2RJB8 Thiamine-monophosphate kinase n=1 Tax=Moorella thermoacetica ATCC
           39073 RepID=Q2RJB8_MOOTA
          Length = 337

 Score =  218 bits (557), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 75/325 (23%), Positives = 116/325 (35%), Gaps = 24/325 (7%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRL-AFSTDSYVIDPLFF----PGGNI 72
           LI  L   A  +P           D A L  E   L   STD  V D  F         I
Sbjct: 11  LIERLKAGAIVDPARVVM--GIGDDAAVLKGEPGFLTLASTDMLVEDIHFTLATATPREI 68

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G   +    +D+A  G IP        L     +E +  +   + E  +  G+ I+ GDT
Sbjct: 69  GYKTMAVNVSDIAAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFGVNIIGGDT 128

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
               R     + IN A +G +  +          GD+LLV+G LG   A +  L      
Sbjct: 129 VSSPRA----MVINLAILGRVENDACLYRHGAQPGDILLVTGDLGGSAAGLDTLLSPRPA 184

Query: 193 DGELVSDCAVLTPL-------IQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
             E+++               I+      G+ A  D +  G+ A V+  A A   GI L 
Sbjct: 185 PAEVIAWARARHFRPTPRVVEIRAALKAGGLTAADDISD-GLVAEVYTLATASRVGIVLE 243

Query: 246 EAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             A+P+ PA R +  +   +     L    + +L++A   +  + V  A++         
Sbjct: 244 AGAIPIAPATRQLAAIYHKEPLDYALYGGEDFELLLACRPDKVDAVREAVNRACR-TPVT 302

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDL 326
           +IG VV  +        G    L  
Sbjct: 303 VIGRVVPAEEGITINHSGRVLPLTP 327


>UniRef50_D2M233 Thiamine-monophosphate kinase n=1 Tax=Bacillus cellulosilyticus DSM
           2522 RepID=D2M233_BACS4
          Length = 327

 Score =  218 bits (557), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 65/323 (20%), Positives = 114/323 (35%), Gaps = 28/323 (8%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRL--AFSTDSYVIDPLF----FPGGNI 72
           I  +         L         D A +     ++    + D+ V    F     P  +I
Sbjct: 8   IRGITPNKHHQQQLKVG----IGDDAAIYGHDKKMESVVAVDTMVEGIHFTKQTMPMKSI 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEE-GLPMETLKAVVTSMAETARAAGIAIVTGD 131
           G  A+    +D+A  GAIP+Y      + +     + L  +   M E A    + ++ GD
Sbjct: 64  GHKALAVNISDIAAMGAIPQYYLVSIAIPKTSWKKKELNDIYNGMNELATVWSMDLIGGD 123

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T        D L I+   +G +             GDV+ V+G LG     +  L E+  
Sbjct: 124 TVSTN----DALVISVTVIGKVEKERRLLRSNARCGDVVFVTGELGLSAYGLQALLEKGY 179

Query: 192 LDGE------LVSDCAVLTPLIQTLRDIPGVK---ALRDATRGGVNAVVHEFAAACGCGI 242
            + +       +       P ++  R +       AL D +  G+ +   E A A    +
Sbjct: 180 ENIDDDELLPYLQAHQKPDPHVRAGRLLANCGYRIALNDISD-GLASEAKEIADASQVTV 238

Query: 243 ELSEAALPVKPAVRGVCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           EL  AA+P    ++   +    +  L    + KLV  + +   E++ AA  +H L     
Sbjct: 239 ELDWAAIPTTNKLKEYPQEKQEEWLLYGGEDFKLVGTIGKENWEKLKAAFQAHSL--PIF 296

Query: 302 LIGEVVERKGVRLAGLYGVKRTL 324
            IG ++      L      +  L
Sbjct: 297 KIGSILTGNSEVLLKKENKREVL 319


>UniRef50_Q31FT3 Thiamine-monophosphate kinase n=1 Tax=Thiomicrospira crunogena
           XCL-2 RepID=Q31FT3_THICR
          Length = 322

 Score =  218 bits (557), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 62/329 (18%), Positives = 113/329 (34%), Gaps = 25/329 (7%)

Query: 17  QLINSLFMEA---FANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGG 70
            +I + F       +   +   +D A L        G++L   TD+ V    F       
Sbjct: 6   DVIETFFKPLSSVASVDEIGIGDDGAVLSC----LAGNQLVVVTDTLVEGVHFPVKTSAY 61

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFIL-EEGLPMETLKAVVTSMAETARAAGIAIVT 129
           NI   A+    +D+A  GA P + S    L  E      L+     + + A    I +V 
Sbjct: 62  NIAWKALAVNLSDLAAMGATPAFYSLALSLPPEKNNQAWLELFAGGLKQLASLYNIPLVG 121

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           GDT        D+L I     G +        +     D++ VSG LG+ G  +  +++ 
Sbjct: 122 GDTTRS-----DRLTITITAQGWVETGNAILRKGAQPDDLIYVSGVLGEGGLGLKAVQQH 176

Query: 190 LGLD--GELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSE 246
                    +      +P +     + G   +  D +  G+ A +    ++      +  
Sbjct: 177 WDEASYASAIQKLNQPSPQVTLGYYLKGLATSAIDVSD-GLLADLKHILSSSQVSAWVDV 235

Query: 247 AALPVKPAVRGVCELLGLD--ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
             +PV  ++R   +        L   ++ +L   V  +    V     +  LG     IG
Sbjct: 236 DLIPVSDSMRTYLQQSNDWSLPLIAGDDYELCFTVHPDNQASVQDL--AKTLGVSLTKIG 293

Query: 305 EVVERKG-VRLAGLYGVKRTLDLPHAEPL 332
           ++V  +G V+L      +  L     E  
Sbjct: 294 QIVAGEGDVQLKNAPENQAHLQSLGFEHF 322


>UniRef50_A6FBC8 Thiamine monophosphate kinase n=1 Tax=Moritella sp. PE36
           RepID=A6FBC8_9GAMM
          Length = 346

 Score =  218 bits (556), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 64/322 (19%), Positives = 111/322 (34%), Gaps = 42/322 (13%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFP---GGNI 72
            LI   F     +    +       D A L V  G +L  +TD+ V    F       +I
Sbjct: 7   DLIGQYFTNK--SVPRDDVITGIGDDCAILSVPAGKQLVVTTDTMVSGIHFLSDANPTDI 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
               +    +D+A  G  P + S    L      E L A   S+ +     G++++ GDT
Sbjct: 65  AHKLVAVNISDIAAMGGQPAWASLALTLP-SFDTEWLSAFSDSLHQQLHRYGVSLIGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL---REQ 189
                     + +     G +            AGD++  SGT+GD  A +  L     +
Sbjct: 124 TKGN------MTLTLTLQGFVEQGKALPRHGAKAGDLIYCSGTIGDANAGLKLLIDANNR 177

Query: 190 LGLDGE--------------LVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEF 234
             L  E              L++     T  + T + + G+  +  D +  G+ + +   
Sbjct: 178 TDLHPENSDEALLTKNDKDYLIARHQRPTARVSTGQALVGIANSCIDLSD-GLASDLKHI 236

Query: 235 AAACG------CGIELSEAALPVKPAVRGVCE--LLGLDALNFANEGKLVIAVERNAAEQ 286
             A            +  +ALP+  A++      L    AL   ++ +L+  V      Q
Sbjct: 237 LKASSRACGVALSANIELSALPLSTALQTYVSKALWPQYALAGGDDYELLFTVSAENKAQ 296

Query: 287 VLAALHSHPLGKDAALIGEVVE 308
           +   +  H L      IGE+V 
Sbjct: 297 LEDVMAEHDL--PYTHIGEIVS 316


>UniRef50_Q97BE7 Hydrogenase expression formation protein HypE n=3 Tax=Thermoplasma
           RepID=Q97BE7_THEVO
          Length = 374

 Score =  217 bits (554), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 67/338 (19%), Positives = 139/338 (41%), Gaps = 23/338 (6%)

Query: 12  GQAMQQLINSLFMEAFA-NPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFFPG 69
           G+  ++      +          +   +  +D   +    G  +A +TD +  DP+F   
Sbjct: 32  GKLDRKFFTESILRYTGYRRPEDKVPPKNGVDTGIISIGNGKVMAVTTDPFYFDPVFG-Y 90

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            +    A    A+D+  +G  P Y++    L   +  E +  +  ++ E A     +I+T
Sbjct: 91  EDSAWFAYHILASDITTAGVYPEYMTVDLNLPISISNEEIARMWKTVHEEAYKYKTSIIT 150

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL----- 184
           G T          +       G    + +        GD+++++ T G   A++L     
Sbjct: 151 GHTARY-ANTGFPMVGGATMFGFTDDDKYVTTAMARPGDIMIMTKTAGIEAASLLTRIFP 209

Query: 185 -NLREQLGLDG-----ELVSDCAVLTPLIQTLR--DIPGVKALRDATRGGVNAVVHEFAA 236
            ++++ LG D      EL    + +   IQ +       + ++ DAT GG+   V+E A 
Sbjct: 210 NHVKKNLGEDKYRYGFELFRKLSTVDEAIQAIEFGTRKAITSMHDATEGGLLGAVYEVAE 269

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
           A G G+ + + A+ V   V+ +  L G+D L   +EG L++ ++   A++ +  L     
Sbjct: 270 ASGNGVSIDKEAIHVDDYVKEIHSLFGIDPLRSISEGTLLMTIDPEYADEFMKRLTK--S 327

Query: 297 GKDAALIGEV-VERKGVRLAGLYGVKRTLDLPHAEPLP 333
           G D+ +IG++  + +G++          +  P  +P  
Sbjct: 328 GIDSYVIGKMTTKDEGIKFKD---GSEPIGEPEKDPFW 362


>UniRef50_B4U7Q4 Thiamine-monophosphate kinase n=3 Tax=Aquificaceae
           RepID=B4U7Q4_HYDS0
          Length = 306

 Score =  217 bits (554), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 63/318 (19%), Positives = 111/318 (34%), Gaps = 38/318 (11%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGGNIG 73
           +LI  L             E+    D A +      L  + D+++ D  F    P   IG
Sbjct: 6   ELIKKLTS--------IIGENTIGDDTAYIKIGETGLNITCDAFLEDVHFLRHYPPEAIG 57

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             AI    +DV  +G  P Y     ++ E +    ++ +   +        + IV G+  
Sbjct: 58  FKAISINVSDVVANGGKPLYGLISLMIPEDIDERFIERIYEGVKSACDFYKLRIVGGNVS 117

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL---REQL 190
                   KL I+   +G I  +          GD ++VSGTLGD       L   +E  
Sbjct: 118 -----KASKLGIDVFLIGEI--DRFVSRAGANVGDDVVVSGTLGDSYTGFRLLTTKKEYE 170

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSEAAL 249
             +  L+      T  I  +  I     A  D +  G+++ +   A      IE+    +
Sbjct: 171 DYELRLIERHLRPTARIDYINHIRKYASACMDISD-GLSSDLWHIAERSNVVIEIDLNKI 229

Query: 250 PVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           P+   +R       L+     L+   + +L+   ++      L             +IG 
Sbjct: 230 PISRELRLYASKENLNPYDIALSGGEDYQLLFCQKKEHFNPFLDN----------TVIGR 279

Query: 306 VVE-RKGVRLAGLYGVKR 322
           V+E  K + L     ++R
Sbjct: 280 VIEQGKALVLVNGKELER 297


>UniRef50_Q2GJY6 Thiamine-monophosphate kinase n=1 Tax=Anaplasma phagocytophilum HZ
           RepID=Q2GJY6_ANAPZ
          Length = 318

 Score =  217 bits (553), Expect = 5e-55,   Method: Composition-based stats.
 Identities = 59/307 (19%), Positives = 98/307 (31%), Gaps = 18/307 (5%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGGNIGKL 75
           I          P L         D A + +       + D  V +  F        + K 
Sbjct: 7   IEKYI-----RPLLRSGFASENDDAAHVSSPTSSFIMTKDVLVENVHFLNHSDPFLLAKK 61

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVV 135
           A+    +D+A  GA P     G  L + +  E  K+    + E      I +  GDT   
Sbjct: 62  ALRVNLSDIASMGATPHSYLLGLSLPKFIDEEWWKSFCAGLQEDNSIFSIKLTGGDTT-- 119

Query: 136 QRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-GLDG 194
                D + I+   +G IP+           GD L VSGT+GD    +L   ++L G   
Sbjct: 120 -NNLADIIVISITALG-IPSANILTRSNAKVGDYLYVSGTIGDAALGLLAYNKKLIGEFS 177

Query: 195 ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
            L     +  P +     I  V +       G+   +       G G  L    +P+   
Sbjct: 178 YLKQRYDLPQPRVMLGTSISNVASACIDVSDGLLQDIGLLCKLSGVGANLYAYEVPLSHE 237

Query: 255 VRGVC---ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG 311
                     L  + L   ++ +L   V      +V     +  +      IG +   +G
Sbjct: 238 AAAAIMQNHDLLENVLAGGDDYELAFTVPPKYCPEVEQI--ATNIKIPVKRIGVITREQG 295

Query: 312 VRLAGLY 318
           +R+    
Sbjct: 296 IRVYDRN 302


>UniRef50_Q6MP56 Thiamine-monophosphate kinase n=1 Tax=Bdellovibrio bacteriovorus
           RepID=Q6MP56_BDEBA
          Length = 318

 Score =  216 bits (552), Expect = 6e-55,   Method: Composition-based stats.
 Identities = 58/333 (17%), Positives = 106/333 (31%), Gaps = 38/333 (11%)

Query: 16  QQLINSL---FMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FP 68
             LI  +         +  +   +D                    D  V    F    F 
Sbjct: 8   WSLIERIRYRVQRQNDHTKVPLGDDAF-----VFRNYPGYSVICQDMMVEGVHFELDYFS 62

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
             ++G  ++    +D+A  GA+P +      L + L    L      M   A    + +V
Sbjct: 63  AFDLGYKSLAVNLSDIAAMGALPHFAQVSLALPKKLNESWLDDFYKGMTSLADDHHMQVV 122

Query: 129 TGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
            GD         D+L ++ +  G+         +    GD+LL SG LG     +  L++
Sbjct: 123 GGDLAASP----DRLVVDVSVHGSCEN--PLTRKGAKPGDLLLCSGPLGLSFTGMTALQK 176

Query: 189 QLGLDGELVSDCAVLTPLIQTLRDIPG----VKALRDATRGGVNAVVHEFAAACGCGIEL 244
           +L    +         P +  +  +      + AL D + G VN  +         G  L
Sbjct: 177 KLSGFDDAKERHLRPKPRLDLVASLQKQHTRIHALMDCSDGLVNDALQ--LRPPNGGFHL 234

Query: 245 SEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
               LP+ P    +   L L+     L    + +L++AV     E             + 
Sbjct: 235 FAENLPLHPDSESLAVDLHLNPQDFVLWGGEDYELLMAVHPEDYEYF----------PEW 284

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
            +IG+  E   V ++     +   +    +  P
Sbjct: 285 KMIGQFTEDPRVFVSHPDHHEEIKEFKGWKHFP 317


>UniRef50_D2QDU8 Thiamine-monophosphate kinase n=1 Tax=Spirosoma linguale DSM 74
           RepID=D2QDU8_9SPHI
          Length = 339

 Score =  216 bits (552), Expect = 7e-55,   Method: Composition-based stats.
 Identities = 63/334 (18%), Positives = 114/334 (34%), Gaps = 40/334 (11%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIG 73
           LI  +     A+            D A      D    STD  V    F     P  ++G
Sbjct: 12  LIERIRQATPASTHPETVR-GIGDDAAVFDWGDDYGLLSTDMLVEGIHFDLTYVPLKHLG 70

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             AI    +D+A    +P  ++    L    P+E +  +   +     A  + +V GDT 
Sbjct: 71  YKAITFGVSDIAAMNGLPVQVTVSIALSSRFPVEAIDELYEGIRAACEAYKVDLVGGDTT 130

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL--- 190
             + G    L I+ + +G +P N+     T    DV+ V+G LG     +  L  +    
Sbjct: 131 ASRSG----LIISVSVLGKVPKNLITYRNTAKPNDVVCVTGDLGAAYLGLQLLEREKQVF 186

Query: 191 ----GLDGELVSDCAVL----------TPLIQTLRDIP-GVKALRDATRGGVNAVVHEFA 235
                +   L  + A L          T ++  LRD+     ++ D +  G+ + +    
Sbjct: 187 LADPNMQPNLSEERAYLVQRQLRPDARTDMVHELRDLGIRPTSMIDISD-GLASELLHLC 245

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAAL 291
              G G  + +  +P+        +   +      LN   + +L+  V     E++ A  
Sbjct: 246 HQSGTGAIIFDENIPIDDQTHLAADEFKISPITAALNGGEDYELLFTVPPQEFEKLSANA 305

Query: 292 HSHPLGKDAALIGEVVERKG-VRLAGLYGVKRTL 324
                      IG +      + LA   G +  +
Sbjct: 306 R-------ITAIGYLTADPKQIVLATKAGQQTPI 332


>UniRef50_A1WVF9 Thiamine-monophosphate kinase n=2 Tax=Ectothiorhodospiraceae
           RepID=A1WVF9_HALHL
          Length = 324

 Score =  216 bits (551), Expect = 8e-55,   Method: Composition-based stats.
 Identities = 74/333 (22%), Positives = 110/333 (33%), Gaps = 25/333 (7%)

Query: 10  SGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF--- 66
            GG+A   LI   F    A       E     D A L  E   LA   D+ V D  F   
Sbjct: 3   GGGEA--ALIQRYFHGLTAQR--DGVELGVGDDAALLQTETGLLAACCDTLVEDIHFPGD 58

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
            P   +G   +    +D+A  GA P +      L E    + L+         A   G+A
Sbjct: 59  IPPEALGHRVLAVNLSDLAAVGARPAWTLLSLTLPEK-DPQWLERFSAGFKALADRYGVA 117

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL 186
           +V GDT          L ++   +G +  +          GD + V+GTLGD    +   
Sbjct: 118 LVGGDTTQGP------LSVSVTALGQVAGDHGLRRGGARPGDGVWVTGTLGDAALGLELW 171

Query: 187 REQL------GLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACG 239
           +E+       G    L        P +      +    A  D +  G+ A +       G
Sbjct: 172 QEREEATALAGDPAYLAGRLFRPEPRVAAGTALLGRASAAIDVSD-GLAADLSRVLDESG 230

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            G  L   ALP   A       L    L+  ++ +L   +     E++  A         
Sbjct: 231 VGATLELEALPRSQAFIDEQGDLRHL-LHGGDDYELCFTLPAEREEEM--ACLREHAATP 287

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
              IG V E  G+R     GV   L+    +  
Sbjct: 288 VTRIGTVEETPGLRGVDAGGVVCALEPGGYDHF 320


>UniRef50_A1AW74 Thiamine-monophosphate kinase n=2 Tax=sulfur-oxidizing symbionts
           RepID=A1AW74_RUTMC
          Length = 309

 Score =  216 bits (551), Expect = 9e-55,   Method: Composition-based stats.
 Identities = 56/299 (18%), Positives = 104/299 (34%), Gaps = 21/299 (7%)

Query: 17  QLINSLFMEAFAN-PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNI 72
            LI + F    +N   L   +D A +D    +    +L  S D+++    F       +I
Sbjct: 5   SLIETYFNWGGSNLANLGIGDDCAVID----IDANYQLVTSVDTFIEGVHFPSNTSASDI 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
              ++    +D+A  GA  +Y +    L   +  + L    TS+   A   GI +V GDT
Sbjct: 61  AYKSLAVNLSDLAAVGARVKYFTLALTLP-NINKKWLSQFSTSLKSLADEFGIVLVGGDT 119

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I     G +  N      +   GD++ VS T+GD       L+     
Sbjct: 120 TKG------MLSITINVTGVVKKNKALLRSSAQVGDLIFVSNTIGDAAYAWKQLQNNQTP 173

Query: 193 DGELVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
              +++      P +   + +  +  A  D +  G+   +         G  ++   +P+
Sbjct: 174 SEYVINQFNRPKPQLFLGQQLSDIANACIDISD-GLEQDLTHILTRSNVGASINLDDIPL 232

Query: 252 KPAVRGVCELLGLD--ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE 308
              V+   E        L   ++ +L           +L AL  +        IG + +
Sbjct: 233 TYEVKTYIEKTNDWCLVLAGGDDYELCFTAPVKNMN-LLKALQ-NKNNITVTQIGIIND 289


>UniRef50_Q3ZZF3 Thiamine-monophosphate kinase n=5 Tax=Dehalococcoides
           RepID=Q3ZZF3_DEHSC
          Length = 336

 Score =  216 bits (550), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 62/327 (18%), Positives = 107/327 (32%), Gaps = 29/327 (8%)

Query: 17  QLINSL-----FMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----F 67
           QLI+ L            P           D A  + +G +L  + DS + +  F     
Sbjct: 10  QLIDRLNILLHQKPDENTPARENLILDIGDDAAVFLPQGYQLV-TVDSLIENVHFNRSML 68

Query: 68  PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAI 127
              ++G  A+    +D+A  G +P+Y      L     + ++     +M   A      I
Sbjct: 69  NWADLGYKALAINMSDIAAMGGLPQYAVVNIDLPPDTLVSSVTDCYNAMYSLANKYQTVI 128

Query: 128 VTGDTKVVQRGAVDKLFINTAGMGAIP-ANIHWGAQTLTAGDVLLVSGTLGDHGATILNL 186
           + GDT          + +    +G+    +         AG  + V+G LG+  A +  L
Sbjct: 129 IAGDTNQSSI-----INLAITLLGSAENPSCLLTRNAAQAGQKIAVTGYLGNAAAGLDML 183

Query: 187 REQLGLDGE----LVSDCAVLTPLI--QTLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
             Q  +  E             P I    L    GV    D +  G+   +         
Sbjct: 184 LNQTEVTDESRRIFYRSFYRPKPRINEARLLVKEGVHCCIDISD-GLVTDLGHILRQSRV 242

Query: 241 GIELSEAALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
              +    LP+ P++R    L   + AL    + +L+        EQ+     S      
Sbjct: 243 SARIELDKLPLHPSLRLSYPLQAQNMALYGGEDYELLFTASAKVIEQI-----SVQSHIP 297

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDL 326
             +IGE++  K   L  +    R L  
Sbjct: 298 VTIIGEIIPGKPEELKLVDKDGRALQP 324


>UniRef50_D0MD26 Thiamine-monophosphate kinase n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MD26_RHOM4
          Length = 358

 Score =  215 bits (549), Expect = 1e-54,   Method: Composition-based stats.
 Identities = 74/340 (21%), Positives = 121/340 (35%), Gaps = 48/340 (14%)

Query: 18  LINSL--FMEAFANPWLAEQEDQARLDLAQLVAEGDRLA--FSTDSYVIDPLFF----PG 69
           LI+ L   +   ++P L         D A      +      +TD+ +    F     P 
Sbjct: 16  LIDRLQTIVADLSDPDLIMG---IGDDAAVYRLPDEETVHVITTDALLEGVHFDRLMTPM 72

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            ++G  AI    +DV    A PRY +    +   + +E ++A    +       G+ +V 
Sbjct: 73  EHLGYKAIAVNVSDVVAMNAEPRYATIAVGIPAKISVEMMEAFYRGVRRACEKYGLVLVG 132

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           GDT      A   L I+   +G          +    GD+L VSG LG   A +  L EQ
Sbjct: 133 GDTT-----AAHTLCISVTVVGEARMEDVIFRRGARPGDLLCVSGDLGAAYAGLKILLEQ 187

Query: 190 LGLDGELVSDCAV-----------------LTPLIQTLRDIP-GVKALRDATRGGVNAVV 231
                E  +D                       +I+  RD     +AL D +  G+ + V
Sbjct: 188 RRALKEKGADYQPDLEPYRYVIQRQLLPEARLDVIRDWRDRGVRPRALIDVSD-GLASEV 246

Query: 232 HEFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQV 287
           H       CG  +  +A+PV    R V +    D    AL    + +L+ A+     E +
Sbjct: 247 HHLCRHSNCGAIVYASAIPVALETREVADHFAEDVDTYALFGGEDYELLFALPPEQLELL 306

Query: 288 LAALHSHPLGKDAALIGEVV-ERKGVRLAGLYGVKRTLDL 326
                         +IGE +   +GV++    G    L+ 
Sbjct: 307 --------DPTSFNVIGEFLPADQGVQVQTPEGAIIPLEP 338


>UniRef50_Q607V1 Thiamine-monophosphate kinase n=1 Tax=Methylococcus capsulatus
           RepID=Q607V1_METCA
          Length = 325

 Score =  215 bits (549), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 59/310 (19%), Positives = 98/310 (31%), Gaps = 20/310 (6%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGD-RLAFSTDSYVIDPLFF---PGGNI 72
           ++I   F  +         E     D A L      RLA +TD+ V    FF       +
Sbjct: 8   EIIRRFF--SGQRVADVNTEIGIGDDCAVLNFTAAARLALTTDTLVAGIHFFSDTDPTRL 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA PR+      L E    E + A        A    + ++ GDT
Sbjct: 66  GHKALAVNLSDLAAMGARPRWALLALTLPEN-DPEWIAAFAQGFFRLAERHRVQLIGGDT 124

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ-LG 191
                     L I    +G +             GD + ++G++G  G  +   +   L 
Sbjct: 125 TRGP------LAITVHALGTVDGRPGVKRAGAKPGDAIYLTGSIGLAGLGLRIRQGAYLV 178

Query: 192 LDGELVSDCAVLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
            D E +       P       +     A  D +  G+ A +         G E+   +LP
Sbjct: 179 PDEEALDRLEAPQPRTDFGIRLGEFASAGIDVSD-GLAADLGHILEQSSVGAEVDWESLP 237

Query: 251 VKPAVRGVCELLGLD--ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE 308
           +   V       G     L   ++ +L        A+    A  +         IG +  
Sbjct: 238 LSAGVGRYVADSGDWQMPLVAGDDYELCFTASPAYAQ--AIASAADATATPVRRIGTIRT 295

Query: 309 RKGVRLAGLY 318
             G+ +    
Sbjct: 296 GSGLIIRRRG 305


>UniRef50_B9XDK5 Thiamine-monophosphate kinase n=1 Tax=bacterium Ellin514
           RepID=B9XDK5_9BACT
          Length = 310

 Score =  215 bits (549), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 64/316 (20%), Positives = 115/316 (36%), Gaps = 32/316 (10%)

Query: 17  QLINSLFMEAFANPWL--AEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGGN 71
           +LI  L     AN  L     +D A LDL         + F TD+ V    F    P   
Sbjct: 5   ELIGKLTRSLPANKSLVTGAGDDCAVLDLGI---PDRLVLFKTDAVVEGFHFTSETPPEK 61

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G+ A+    +D+A     P        L     ++ ++ +   + E AR   ++I  G+
Sbjct: 62  VGRKALGRCISDIAAMAGTPNSALITLALPRHYDLDYVEGIYAGLGELARKFDVSIAGGE 121

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T        +++ I+ + +G +            AGD + V+G LG   +      + L 
Sbjct: 122 TTTNP----ERILISISLLGTVEREKCIFRSGALAGDAIFVTGELGGSISG-----KHLD 172

Query: 192 LDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
            +  L             LRD   + ++ D +  G+   +     A   G EL  +A+PV
Sbjct: 173 FEPRLTEAH--------WLRDHFAIHSMIDLSD-GLAGDLRHLLKASHVGSELMASAIPV 223

Query: 252 KPAVRGVCELLG------LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
               +   +         L AL    + +L+  +    A  +L            + IG+
Sbjct: 224 SREAKLASKAESSAKPPLLAALTDGEDFELLFTIASKDAVPLLDGWKHQFPKVKLSCIGK 283

Query: 306 VVERKGVRLAGLYGVK 321
           V   +G+ L    G++
Sbjct: 284 VTAGEGINLRDKQGIR 299


>UniRef50_C3K2R7 Thiamine-monophosphate kinase n=3 Tax=Gammaproteobacteria
           RepID=C3K2R7_PSEFS
          Length = 321

 Score =  215 bits (548), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 64/314 (20%), Positives = 110/314 (35%), Gaps = 25/314 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFPGGN---I 72
           +LI + F  A               D A L +  G++LA STD+ V    F    +   +
Sbjct: 5   ELIRNYFAAAPCAQGGEGIALGIGDDCALLALPTGEQLAISTDTLVAGVHFADPCDPFLL 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ ++    +D+A  GA P   +        +  + L+     +   A+  G+ +V GDT
Sbjct: 65  GQRSLAVAVSDLAAMGAHPLAFTLALTTP-TVDADWLQRYAQGLNAMAQRCGVGLVGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L +    +G +PA           GD+L V G LG+    +  +  Q   
Sbjct: 124 TRGP------LSLTLTVLGRVPAGQALTRSGARPGDLLCVGGELGNAAGALPLVLGQRSA 177

Query: 193 DGELVSDC-----AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
           D  +         +    L   L       +  D +  G+ A     A A    + +   
Sbjct: 178 DAAIADPLLAHYWSPQPQLALGLALRGKATSAMDISD-GLLADCGHIATASQVSLLIERQ 236

Query: 248 ALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
            LP+  A+      +   + AL+  ++  L   +       +LA       G    +IG 
Sbjct: 237 RLPLSTALLAFVGDDEARVAALSGGDDYVLAFTLPPAELAPLLA------DGLPIHVIGR 290

Query: 306 VVERKGVRLAGLYG 319
           V   +GV L    G
Sbjct: 291 VEPGQGVTLLDADG 304


>UniRef50_D1PUY6 Thiamine monophosphate kinase n=6 Tax=Prevotella RepID=D1PUY6_9BACT
          Length = 370

 Score =  215 bits (548), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 51/360 (14%), Positives = 105/360 (29%), Gaps = 68/360 (18%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIG 73
           LI+ +  +   N   +        D A +      +  +TD  +    F         +G
Sbjct: 11  LIDHITKDIQLNNASSIF--GIGDDCAVMHYPNTEVLITTDMLMEGIHFDLTYVTMQELG 68

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A     +D+      PR ++    + +   +E ++A    +        I IV GDT 
Sbjct: 69  YKAAMENISDIFAMNGTPRQMTVSMAIGKRFKVEDIEAFYKGLRSACDKWSIDIVGGDTT 128

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
                    L I+   +G                D++ V+G LG     +  L  +  + 
Sbjct: 129 SS----YTGLAISITCIGEARKEDIVYRNGAKETDLVCVTGDLGAAYMGLQLLEREKEVY 184

Query: 194 GELVSDCAVLTPLIQTLRDIPGV------------------------------------- 216
            + + D        Q   +   V                                     
Sbjct: 185 YQQIDDINRKIKEAQKAGNEEAVKHFQEQGSHIANFQPDFAGKEYLLERQLKPEARGDMI 244

Query: 217 ----------KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD- 265
                      A+ D +  G+++ +        CG  + E  +P+      + E L ++ 
Sbjct: 245 QLLREHNIRPTAMMDISD-GLSSELLHICKRSNCGCRIYEKNIPIDYQTAIMAEELNINV 303

Query: 266 ---ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK-GVRLAGLYGVK 321
              A+N   + +L+        +++     +         IG + + + GVRL      +
Sbjct: 304 TTAAMNGGEDYELLFTCPIGDHDKLQDLEEA-----GVKQIGYITKPELGVRLISRDQQE 358


>UniRef50_Q2JTF1 Thiamine-monophosphate kinase n=11 Tax=Cyanobacteria
           RepID=Q2JTF1_SYNJA
          Length = 340

 Score =  215 bits (548), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 63/299 (21%), Positives = 106/299 (35%), Gaps = 30/299 (10%)

Query: 39  ARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVAVSGAIPRYL 94
              D A L A   +L  STD  V    F     P   +G  A+    +D+A  G+ PR L
Sbjct: 42  VGDDGAVLPAPEGQLVVSTDVLVEGVHFSDVTTPAHAVGWRAVAANLSDLAAMGSRPRAL 101

Query: 95  SCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIP 154
             G  L    P+  ++ +   M       G  +V GD     +      F+    +G++ 
Sbjct: 102 VVGLGLPGSTPVAWVEELYEGMRACCARWGAELVGGDLCRSPQR-----FVAITALGSVQ 156

Query: 155 ANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE-------LVSDCAVLTPLI 207
                  +    GD L+V+G  GD  A +  L                L+       P +
Sbjct: 157 PGRAIERRRAQPGDWLVVTGPHGDARAGLELLLHPEQGSSATAAQRQQLIRAHQYPRPRL 216

Query: 208 QTLRDIPGV-----KALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELL 262
             L  +  +      A  D T  G+   + +   + G    ++   +P+  A+R      
Sbjct: 217 DVLSLLEALPGPLRLAGMD-TSDGLADALVQVCQSSGVAARIAAERIPISVALRQAFPAQ 275

Query: 263 GLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE-RKGVRLAGLYG 319
            L+  L    + +L+++ E + A+ +L  L        AA IGEV        +    G
Sbjct: 276 ALEWALYGGEDFELLLSAEVSVAKHLLEKLP------GAAWIGEVTGWDPQGTVRLQDG 328


>UniRef50_B1I671 Thiamine-monophosphate kinase n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I671_DESAP
          Length = 337

 Score =  215 bits (548), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 75/325 (23%), Positives = 116/325 (35%), Gaps = 28/325 (8%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLA-FSTDSYVIDPLF----FPGGNI 72
           L+  L       P +      A  D A L   G  L  F+ D+ V +  F        ++
Sbjct: 11  LVERLLGRLARGPGVVRG---AGDDAAVLDLGGKELLLFTVDTLVEEVHFSRAYGSMRDL 67

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +DVA  G  P Y            +  +  +   +A TA   G+ +V GDT
Sbjct: 68  GAKAMAVNLSDVAAMGGRPVYAVVSLAAPAETAVADIDDLYAGLAGTAARYGVTLVGGDT 127

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-- 190
                G    L I  A +G          +   +GD+  V+G+LG   A +   +     
Sbjct: 128 VRHPHG----LVITVALLGLAGRERVLYRKGAVSGDLFYVTGSLGASAAGLFLFQNPHPA 183

Query: 191 ---GLDGELVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
               ++  L        P +     L     V A  D +  G+   V     A G G  L
Sbjct: 184 CPPEVEDRLKKAHLSPEPRVVAGGLLAASGVVSAAEDISD-GLALTVAHICTAGGVGARL 242

Query: 245 SEAALPVKPAVRGVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
               +P+ P VR +  L G D L +      + +L+  V   AA  +   + +   G   
Sbjct: 243 LADRVPLSPEVRRLGILTGKDPLEWALFGGEDYELLFTVRPGAAAGLEREMAAA--GWPV 300

Query: 301 ALIGEVV-ERKGVRLAGLYGVKRTL 324
             IGEV+   +G+ L    G  R L
Sbjct: 301 TWIGEVLGPGEGLWLEDAAGAGRPL 325


>UniRef50_B9KYQ7 Hydrogenase expression/formation n=2 Tax=Thermomicrobia (class)
           RepID=B9KYQ7_THERP
          Length = 343

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 87/337 (25%), Positives = 137/337 (40%), Gaps = 24/337 (7%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+   QL+         +P +         D A +  +  RL F +D     P+ F    
Sbjct: 9   GKLPPQLLAEFLGNLSPDPSVLLG-PGIGHDAAVIQIDTIRLVFKSD-----PITFATEA 62

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           IG  A+   ANDVA  GA PR+     +L EG      + ++  +A  A   G+++V G 
Sbjct: 63  IGWYALNVNANDVACLGARPRWFLATVLLPEGTTAHDAQVILDDLARAAERLGVSVVGGH 122

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE--- 188
           T++     +D+  +    +G +          +  GD LL+   +   G  +L       
Sbjct: 123 TEIT--VGLDRPIVAGTMIGELTTEYVLSPARVRPGDALLLVRGIAIEGTALLARECRQT 180

Query: 189 -QLGLDGELVSDCAVL--------TPLIQTLRDIPG--VKALRDATRGGVNAVVHEFAAA 237
            +  LD +L++ C            P    L +  G  ++ L D T GG+   +HE A A
Sbjct: 181 LERMLDQDLLARCRRFLYEPGISIVPAATLLLERLGEDLRYLHDPTEGGLATGLHEVAVA 240

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
           CG G+ +SE A+ V P  R VC  LGLD L     G L+  V   + E  L  L  H   
Sbjct: 241 CGTGLVVSEEAILVYPETRAVCTALGLDPLGLIASGALLAVVTPESVEHALDTLAQHD-- 298

Query: 298 KDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
             A  +G +    G R+      +R L +   + + R
Sbjct: 299 IPATQLGWLDPDPGRRVLIGSTGERPLPVFQVDEVAR 335


>UniRef50_B7V7Q7 Thiamine monophosphate kinase n=11 Tax=Gammaproteobacteria
           RepID=B7V7Q7_PSEA8
          Length = 322

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 75/318 (23%), Positives = 116/318 (36%), Gaps = 25/318 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFFPGGN---I 72
           +LI   F  A      A+       D A L    G++LA STD+ V    F  G +   +
Sbjct: 5   ELIRRFFAAAACAAPAADVALGIGDDCALLAPPAGEQLAVSTDTLVEGVHFPAGCDPFLL 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
            + A+  +A+D+A  GA P   +    L +    E L+     +   AR  G+A+V GDT
Sbjct: 65  AQRALAVSASDLAAMGAAPLAFTLALTLPQA-DAEWLQGFARGLDAMARQCGLALVGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L +     G +PA           GD+L V G LG+ GA +  + E+   
Sbjct: 124 TRGP------LSMTLTVFGRVPAGQALTRAGARPGDLLCVGGPLGEAGAALELVLERRSA 177

Query: 193 DGELVSDCAVLTPLIQT-----LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
             E+                  L       A  D +  G+ A     A A G  + +   
Sbjct: 178 PAEVAEPLLARYWTPAPQFGLGLALRGKASAALDISD-GLLADCGHIARASGVALLVECQ 236

Query: 248 ALPVKPAVRGV--CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
            L    A+ G+   E      L   ++  LV  +      ++ AA  +       A+IG 
Sbjct: 237 RLQASAALSGLLAGEEALRQQLAAGDDYVLVFTLPPEYLGEIRAAWPAT------AVIGR 290

Query: 306 VVERKGVRLAGLYGVKRT 323
           V   +GV L    G +  
Sbjct: 291 VEAGQGVHLLDADGKELI 308


>UniRef50_C5BS83 Thiamine-phosphate kinase n=1 Tax=Teredinibacter turnerae T7901
           RepID=C5BS83_TERTT
          Length = 315

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 72/307 (23%), Positives = 111/307 (36%), Gaps = 27/307 (8%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFP---GGNI 72
            LI   F  A   P +A        D A L +   ++LA S D+ V D  F        +
Sbjct: 7   DLIRDYFARAQDAPGVALG---IGDDCALLEIPPSEQLAVSVDTLVADVHFPADAEPYLV 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
            + A+C + +D+A  GA PR+++    L        L      +    +A G ++V GDT
Sbjct: 64  AERALCVSLSDLAAMGAQPRWITLCLTLP-AFDEAWLAGFSAGLFSRTKAYGCSLVGGDT 122

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG- 191
                     L I+   MG +P       +    GD + VSG LGD  A +  +R +L  
Sbjct: 123 TRGP------LAISVQVMGTVPVGQALRRKGAQVGDGIYVSGPLGDGAAALALVRGELET 176

Query: 192 ---LDGELVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSEA 247
                  L        P       + G+  A  D +  G+   +    ++ G    +   
Sbjct: 177 TPSESAYLRERYFQPEPCFGWGHALRGIANAAIDVSD-GLVQDLGHICSSSGVAGLVYLE 235

Query: 248 ALPVKPAVRGV-CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
            LP   AV  +        AL   ++ +L   V       +        L   A  IG+V
Sbjct: 236 RLPFSAAVNRLDTTARYQAALAGGDDYQLCFTVPAARQSALEE------LELTAFRIGDV 289

Query: 307 VERKGVR 313
           V   GVR
Sbjct: 290 VAGSGVR 296


>UniRef50_B4RQH6 Thiamine monophosphate kinase n=28 Tax=Neisseriaceae
           RepID=B4RQH6_NEIG2
          Length = 318

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 65/327 (19%), Positives = 117/327 (35%), Gaps = 25/327 (7%)

Query: 17  QLINSLFMEAFA-NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNI 72
             I          +  L   +D A +       EG  L FS D  + D  FF       +
Sbjct: 5   DFIKRYLQTGTDKDVVLGIGDDAAIVR----PREGFDLCFSADMLLKDRHFFADVKPEGL 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
               +    +D+A  GAIPR++     L E L    L+    S    A+  G+ ++ GDT
Sbjct: 61  AWKVLAVNISDMAAMGAIPRWVLLSAALPE-LDEVWLERFCGSFFGLAKKFGVTLIGGDT 119

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     +  N   +G +P           AGD + VSG +G   A +    ++  L
Sbjct: 120 TKGD------MAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRVGMAAAALNCRLKRCVL 173

Query: 193 DGELVSDC-----AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
             ++ ++C          +   L  +P  +A +D +  G+   +     A G G E+   
Sbjct: 174 PDDVFAECEQKLLRPEPRVGLGLALLPFARAAQDVSD-GLAQDLGHILTASGVGAEIWAD 232

Query: 248 ALPVKPAVRGVCELLGL--DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           +LP    ++ +          L   ++ +LV     +   +VL A  +   G     IG+
Sbjct: 233 SLPSLSVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLDA--AERCGVPVTCIGK 290

Query: 306 VVERKGVRLAGLYGVKRTLDLPHAEPL 332
           +     +++    G +  L     +  
Sbjct: 291 INGGCRLKVLDAGGRELELHSLGFDHF 317


>UniRef50_C8R1R1 Thiamine-monophosphate kinase n=1 Tax=Desulfurivibrio alkaliphilus
           AHT2 RepID=C8R1R1_9DELT
          Length = 341

 Score =  214 bits (546), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 67/306 (21%), Positives = 105/306 (34%), Gaps = 25/306 (8%)

Query: 38  QARLDLAQLVA-EGDRLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPR 92
               D A            +TD+ V    F     P   +G+ A+    +D+A  G  PR
Sbjct: 30  GIGDDCAIWQPTPATDSLVTTDTLVEGVHFDRRWHPPRLLGRKAVAVNMSDIAAMGGTPR 89

Query: 93  YLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA 152
           Y      L E      L+ ++  +AE   A G  ++ GDT        ++L +    +G 
Sbjct: 90  YALLSLGLGEAENPAWLEMMLDGLAEAVAAYGAVLIGGDTVKSP----ERLLLTVTIIGE 145

Query: 153 IPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVS------DCAVLTPL 206
            PA+         AGD + V G LG     +   R  L  D +         D      L
Sbjct: 146 SPASRACLRSGGQAGDSIWVGGPLGLAAGGLELCRRDLAADPQWQEAVQAHLDPPAQVEL 205

Query: 207 IQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA 266
            + L     V A+ D +  G+   +    AA G G E+    LPV   +     +   D 
Sbjct: 206 GRRLAAAGVVHAMMDLSD-GLATDLAHICAASGVGAEVEAELLPVPDLLHRAAAVCQADP 264

Query: 267 LNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE----RKGVRLAGLY 318
           LN+      + +L+   +    +  +A L           IG +        GV L    
Sbjct: 265 LNWALCGGEDYRLLFTADPAR-DGAIAELGRDLADTTLTRIGRLTAPPPGGPGVLLRTAD 323

Query: 319 GVKRTL 324
           G  R +
Sbjct: 324 GQSREI 329


>UniRef50_B6YUV4 HypE n=3 Tax=Thermococcus RepID=B6YUV4_THEON
          Length = 332

 Score =  214 bits (545), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 77/331 (23%), Positives = 123/331 (37%), Gaps = 21/331 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQ-EDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFFPG 69
           G+    ++  +         +      +   D A L  +    L  +TD      L  P 
Sbjct: 6   GKLRNDVLREVVFPNIGIEDVRVIYGPREGFDSAVLEYDHEHYLIVATDP----TLGVPE 61

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
              G       A+DVAV GA PR+L    +   G     L+ ++ S+    R  G +I+ 
Sbjct: 62  ETFGFFTYHFAASDVAVFGARPRWLIVDLLFPPGTERSFLENIMRSLNTECRKYGSSIIG 121

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           G T      A  +    T  MG +  +          GD ++V+  +G   A       +
Sbjct: 122 GHTGAYPTIA--EPTSTTTAMGLVRKDELKLPL-AEPGDKIIVTAKIGLEFAVSAAYFRE 178

Query: 190 LGLDGEL----VSDCAVL----TPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
             L   L    +     L    T L   L   P V+ + DAT GG+   +HE A   G G
Sbjct: 179 EELRKFLTFKEIERLKRLFTFETALPDALIARPFVRGMHDATEGGL-TALHEIAENSGVG 237

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             +    L + P VR V E  GL+  + ++ G L+       A+ ++  L+ +  G  A 
Sbjct: 238 FRVYADRLYLDPLVRKVLEFYGLEPWSVSSTGTLIAITPPEKADALITELNKN--GIMAF 295

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
            +GE  E K   L    G ++T      +P 
Sbjct: 296 ELGEFTEEKERVLV-KGGKEKTFPTFERDPY 325


>UniRef50_A0LIX8 Thiamine-monophosphate kinase n=1 Tax=Syntrophobacter fumaroxidans
           MPOB RepID=A0LIX8_SYNFM
          Length = 340

 Score =  214 bits (545), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 66/332 (19%), Positives = 126/332 (37%), Gaps = 28/332 (8%)

Query: 6   LAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEG-DRLAFSTDSYVIDP 64
           +  G  G+   +LI  +    F      +       D+A L   G + L  + D+ V + 
Sbjct: 1   MRIGEFGEF--ELIRRI--GTFLPGPPGDVVVGIGDDVAVLNVSGPEYLLATCDAQVENI 56

Query: 65  LF----FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA 120
            F         +G+  +    +D+A  G  P++      L     ++ +  +   M E  
Sbjct: 57  HFIRAATTPYQLGRKIVAINVSDIAACGGRPKWALVSLALTPDTGVDFVDGLYAGMQEEI 116

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHG 180
            AAG +IV G+      G   ++ I+ + +G +            +GD++LV+GTLG+  
Sbjct: 117 HAAGASIVGGNL----SGIRGEIVIDLSLLGTVSPECLILRNGARSGDLVLVTGTLGESR 172

Query: 181 ATI-LNLREQLGLDGELVSDCAVLT-------PLIQTLRDIPGVKALRDATRGGVNAVVH 232
           A + L LR +L ++ E                   + L     + A+ D +  GV   + 
Sbjct: 173 AGLELILRPELEVEQEAGDRVRARHLTPGARLREGRILAATGSIHAMADVSD-GVLGDLG 231

Query: 233 EFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVL 288
               A     E+   +LP+ P    V E+   D    AL+   + +L+   +     ++ 
Sbjct: 232 HICRASEVQAEIWPESLPISPECLRVAEVARCDAVQWALSGGEDYELLFTADPRRVPEIR 291

Query: 289 AALHSHPLGKDAALIGEVV-ERKGVRLAGLYG 319
             L +   G    +IG +  + + V +    G
Sbjct: 292 GRLEAET-GTSCHVIGRITGKGEAVLVRSREG 322


>UniRef50_B5Y6B6 Hydrogenase expression/formation protein HypE n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y6B6_COPPD
          Length = 339

 Score =  214 bits (545), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 65/296 (21%), Positives = 108/296 (36%), Gaps = 19/296 (6%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
               D+A      D L    D     P+      IG LA+    ND+A SG  PR++   
Sbjct: 31  AFGEDVAVTRVGDDLLLSHVD-----PIVGAVNGIGWLAVHVACNDIAASGIKPRWVQLL 85

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
            +L      E LK +++  A  A +  + I+ G T+      + +  +    +       
Sbjct: 86  VMLPSLDQPEELKQIMSDAARAADSLNVTIIGGHTEAS--NGLRRPLVAATALAPACGKR 143

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILN-----LREQLGLDGELVSDCAVLTPLIQTLRD 212
                    GD++ V+  +G  G  IL         + GL  + +++   L   +  + +
Sbjct: 144 VVRTSGAKPGDIIYVTRGVGLEGTGILASDFAVEARKRGLTDQDLNEALKLLSSVSVVSE 203

Query: 213 I-----PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDAL 267
                  G  A+ D TRGG+   + E A+  G  +E+  + +PV   V+        D L
Sbjct: 204 ALKLADLGATAMHDVTRGGILETLLEIASCSGVCMEVDRSRIPVPEVVKRFANAFEFDPL 263

Query: 268 NFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRT 323
              + G LV  +     E   A   + P       IG V E +GV L         
Sbjct: 264 KMISSGTLVATLPPEMCETAEALFENQP--CKLFRIGVVTEGRGVLLRSGSESHLY 317


>UniRef50_Q2RZV6 Thiamine-monophosphate kinase n=1 Tax=Salinibacter ruber DSM 13855
           RepID=Q2RZV6_SALRD
          Length = 360

 Score =  213 bits (544), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 69/336 (20%), Positives = 121/336 (36%), Gaps = 45/336 (13%)

Query: 22  LFMEAFANPWLAEQEDQARLDLAQLVAEGDRL-AFSTDSYVIDPLF----FPGGNIGKLA 76
           L  +    P           D A    + DR+   +TD+ V    F     P  ++G  A
Sbjct: 23  LLRDTLGEPTDDTIVSGIADDAAVYRTDEDRVHVMTTDTLVEGVHFDRAFMPMEHLGFKA 82

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           +    +DV    A PRY +    + + + +E +  V   + +   A  + IV GDT    
Sbjct: 83  LSVNVSDVVAMNASPRYATVSIGIPQNVSVEMITTVYEGLKQACDAYDMHIVGGDTNAS- 141

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL--------NLRE 188
                 L ++ + +GA              GD + V+G LG   A +            +
Sbjct: 142 ----HGLSLSISVVGAAAEEDVVYRTGAQVGDKICVTGDLGSSYAGLKVLLRNRERLQEQ 197

Query: 189 QLGLDGEL------VSDCAVLTPLIQTLRDIPGV----KALRDATRGGVNAVVHEFAAAC 238
           +   + +L      +         ++T+RD         AL D +  G++A VH    A 
Sbjct: 198 EEDFEPDLDPYSYVIRRHLAPPAQLKTVRDWGDAGVQPHALIDISD-GLSAEVHHICEAG 256

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALHSH 294
             G +L E ALP+ P  R      G D    AL    + +LV  +  +  + +       
Sbjct: 257 DLGAQLYEPALPIDPETRNTATDFGEDVTIYALFGGEDYELVFTIPEDELDAL------- 309

Query: 295 PLGKDAALIGEVVE----RKGVRLAGLYGVKRTLDL 326
              +   ++GE+VE       +++   +G    L  
Sbjct: 310 -DPQTYTVVGEIVEPDDPEHPIKIQRAHGENVPLQP 344


>UniRef50_B9ZS01 Thiamine-monophosphate kinase n=1 Tax=Thioalkalivibrio sp. K90mix
           RepID=B9ZS01_9GAMM
          Length = 324

 Score =  213 bits (543), Expect = 8e-54,   Method: Composition-based stats.
 Identities = 77/330 (23%), Positives = 123/330 (37%), Gaps = 30/330 (9%)

Query: 17  QLINSLFMEAFA---NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GG 70
            LI   F E      +  L   +D A L +      G  L  S D+ V    +FP     
Sbjct: 9   DLIRRYFAEPAGTSPDVRLGIGDDAALLGVQA----GHELVVSVDTMVEGTHYFPDHPPA 64

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A+    +D+A  GA P        L   +  + L A        A  A + +V G
Sbjct: 65  SLGHKALAANLSDLAAMGADPLGAVLSLTLP-SVDHDWLAAFSRGFLALAEQASVPLVGG 123

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT            I+   +G +PA           GD L+VSG LG   A +   +++ 
Sbjct: 124 DTTRGPGA------ISVTVLGQVPAGQALRRAGARPGDRLVVSGALGGAAAGLAFEKQRR 177

Query: 191 G---LDGELVSDCAVLTPLIQTLRDIPG----VKALRDATRGGVNAVVHEFAAACGCGIE 243
                  E   DCA L      L    G     +A+ D +  G+ A +   AAACGCG  
Sbjct: 178 AQGRPPDEESPDCARLFWPSARLALGRGLRNRARAVIDISD-GLLADLGHLAAACGCGAR 236

Query: 244 LSEAALPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           +  + LPV P + G  E +  D  L    + +L+ A+      ++L+      +     +
Sbjct: 237 VDWSQLPVDPLLEGQPEEMVRDCVLAGGEDYELLFALPPTEPLELLSL----SVRTSLTV 292

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           IGE      + +   +G +  +     +  
Sbjct: 293 IGEFTSGSDIEVVDAHGARLDVARRGHDHF 322


>UniRef50_Q1N2P0 Thiamine monophosphate kinase n=1 Tax=Bermanella marisrubri
           RepID=Q1N2P0_9GAMM
          Length = 305

 Score =  213 bits (542), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 62/306 (20%), Positives = 101/306 (33%), Gaps = 37/306 (12%)

Query: 17  QLINSLFME---AFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFF---PG 69
            +I   F +    F +P +         D A ++ +    L FS D+ V    F      
Sbjct: 5   DMIKQYFQDPQLHFPHPNVRFG---IGDDCASILPDENHELVFSMDTLVDGVHFLQTSNS 61

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            +IG  A+C T +D+A   A P   +    + E      L+     +AE A+     IV 
Sbjct: 62  FDIGTRALCVTLSDLAAMAATPIGFTLALTIPEAHST-WLQGFSQGLAEIAQRFHCPIVG 120

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           GDT            I     G +             GD + VSG LGD    +  + E 
Sbjct: 121 GDTTRGPHC-----VITIQVHGQVKKGKALMRSGAKPGDKVFVSGDLGDGAGALSQVLEN 175

Query: 190 LGLDGELVSDCAVLTPLIQTLRDI-PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
                 L        P I+  + I     +  D +  G+   +     A   G+ +   +
Sbjct: 176 PLDSTGLAQRYFQPLPEIEFAQAIQSYATSGMDISD-GLLQDLEHICRASQVGMMIDPES 234

Query: 249 LPVKPAVR---GVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           +P+   +    G    +   AL   ++ +LV     + A  +               IGE
Sbjct: 235 IPMSADLIDKVGYQRAMKF-ALTGGDDYRLVYTA-PDCAHGIQ--------------IGE 278

Query: 306 VVERKG 311
           VV    
Sbjct: 279 VVAEPK 284


>UniRef50_D1J9H7 Thiamine-monophosphate kinase n=1 Tax=uncultured archaeon
           RepID=D1J9H7_9ARCH
          Length = 335

 Score =  213 bits (542), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 54/324 (16%), Positives = 119/324 (36%), Gaps = 25/324 (7%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNI 72
           ++++    ++       A  +D A +D+ ++      L  +TD+      F        +
Sbjct: 13  ERIVEKFRVDREMVTVGAGDDDCAVIDIEKVRNRFKHLVITTDTLQESTHFPHGISAFQM 72

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G   +    +DVA  GA P   +    +        L  +V  + + A +   ++V GD 
Sbjct: 73  GWSIVAVNLSDVAAMGAYPFAFTIAMGIPAQTETSFLDELVAGIEKCAASYNTSVVGGDI 132

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
            +       +L +     G    +          GD++ V+G+LG+    +  +R +L +
Sbjct: 133 TMS-----KELILTGTCFGFA--DRPVRRAGAKEGDLICVTGSLGNAALALKLMRGELKV 185

Query: 193 DG----ELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELS 245
            G    E+    +   P I     + +     ++ D +  G+   + E A     G+EL 
Sbjct: 186 PGDVGVEVKKALSQPVPRINEGITIANSGVATSMIDISD-GLALSLAEIAKRSSVGVELY 244

Query: 246 EAALP-----VKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           E  +P     ++  +R         A  F  + +L+  ++  A E     +         
Sbjct: 245 EDKVPVLSDEIRSDLRLSTREQRELAYYFGGDYELLFTIDAGALEN-EQVMSELIKEVKM 303

Query: 301 ALIGEVVE-RKGVRLAGLYGVKRT 323
           ++IG++V   +G+        ++ 
Sbjct: 304 SVIGKIVPQNEGIYFKNGEEKEKV 327


>UniRef50_UPI0001C16452 Thiamine-monophosphate kinase n=2 Tax=Nostocaceae
           RepID=UPI0001C16452
          Length = 349

 Score =  212 bits (541), Expect = 1e-53,   Method: Composition-based stats.
 Identities = 57/315 (18%), Positives = 104/315 (33%), Gaps = 43/315 (13%)

Query: 30  PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVA 85
           P     +D A L           L  +TD  V    F        + G  A     +D+A
Sbjct: 28  PPHIIGDDGAVL----PTKPAHHLVVTTDMLVDGVHFSNLTTSPKDAGWRAATANLSDLA 83

Query: 86  VSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI 145
             GA P  ++    L   L +  ++ +   M++  +     IV GD             I
Sbjct: 84  AMGASPLGITVALGLPGDLAVNWVEQLYQGMSDCLQKYHTPIVGGDIVRSPVT-----TI 138

Query: 146 NTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE-------QLGLDGELVS 198
                G +  ++     T   G+ ++++G  G   A +  L         +      L+ 
Sbjct: 139 GITAFGEVSPDLIIRRCTAQVGNAIVITGMHGASRAGLELLLHPQTGENLKEEEKQALIR 198

Query: 199 DCAVLTPLIQTLRDIPGV---------------KALRDATRGGVNAVVHEFAAACGCGIE 243
                 P +  +  +  +                +  D +  G+   + +   A   G  
Sbjct: 199 FHQRPNPRLDVIYVLHEILISGLKPRGDSSPVTLSGMD-SSDGLADAILQICRASQVGAV 257

Query: 244 LSEAALPVKPAV-RGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           L +  +P+ P     +  L  LD AL    + +LV+ +    A+ ++  L     G  AA
Sbjct: 258 LHQDKIPLVPISNNWLTPLRWLDYALYGGEDFELVLCLPPTIAKALVLKL-----GSGAA 312

Query: 302 LIGEVVERKGVRLAG 316
           +IGE+     V L  
Sbjct: 313 IIGEITSGDQVILQS 327


>UniRef50_D1AS58 Thiamin-monophosphate kinase n=5 Tax=Anaplasma RepID=D1AS58_ANACI
          Length = 349

 Score =  212 bits (540), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 54/306 (17%), Positives = 102/306 (33%), Gaps = 18/306 (5%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGGNIGKL 75
           I          P +         D  ++ +       + D  V    F        + K 
Sbjct: 40  IEKYI-----RPLMRSGFSTENDDAGKISSPNGSFIVTQDILVEGTHFLRHSNPTLLAKK 94

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVV 135
           A+    +D+A  GA P     G  L +G+  E  +     + E  +   + ++ GDT   
Sbjct: 95  ALRVNLSDLAAMGAQPYGYMLGMSLPQGVTEEWWEQFSNGLREDNKNYNVNLIGGDTTSN 154

Query: 136 QRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG- 194
             G    + I+   MG +P            GD L VSG +GD    ++  ++ +G +  
Sbjct: 155 NTGT---ITISITAMG-VPGMQSMTRSQAKVGDFLYVSGNIGDATLGLMAYQDLIGGEYF 210

Query: 195 ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
            L     +  P I     I G+ +       G+   +         G  +    +P+  A
Sbjct: 211 ALKRRYDLPEPRITLGSKICGIASACIDISDGLVQDIGHICRLSNVGASIHLNQIPMSDA 270

Query: 255 VRGVCE---LLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG 311
            + V      L     +  ++ +L      +   +++    +  LG     IG +V + G
Sbjct: 271 AQDVLRRNPELIERICSGGDDYELAFTSAESNHTKIMHI--AADLGVKVTTIGVIVRQPG 328

Query: 312 VRLAGL 317
           V +   
Sbjct: 329 VEVYDG 334


>UniRef50_Q0BTF2 Thiamine-monophosphate kinase n=2 Tax=Acetobacteraceae
           RepID=Q0BTF2_GRABC
          Length = 331

 Score =  212 bits (540), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 64/316 (20%), Positives = 109/316 (34%), Gaps = 19/316 (6%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN---IGKL 75
           I        A   L   +D A L        G  L  + D+ V    + PG +   + + 
Sbjct: 21  IARYLAPLAAAGGLNLTDDAALLQ----PPPGLSLVLAADAMVEGVHYLPGTDPHLLARK 76

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPME-TLKAVVTSMAETARAAGIAIVTGDTKV 134
            +    +D+A  GA P +      L  G        A    +AE     GI ++ GDT  
Sbjct: 77  LLRVNLSDLAAMGAAPLHYLMTLALPRGTDPAPWFTAFTAGLAEDQGIFGITLLGGDTTS 136

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
           ++  A     ++   +G +        Q     D + V+GT+GD    +L L E L    
Sbjct: 137 IKGPA----CLSLTVIGTVEPGKAVRRQGACPDDEIWVTGTIGDGALGLLALTEGLADPD 192

Query: 195 ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPA 254
           + ++    L      L D   V+A  D +  G+   +     A G    +    +P+  A
Sbjct: 193 DFLAGRYHLPSPRLGLIDQSLVQAAADISD-GLLQDLGHLCTASGLDALVEADTVPLSDA 251

Query: 255 VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE----RK 310
            R          L+  ++ +LV+AV  +    +     +  LG     IG        + 
Sbjct: 252 ARRHMPEYLPLCLSGGDDYELVMAVSPSCTVPLRQ--RADSLGIPVQRIGRFHARSGQKP 309

Query: 311 GVRLAGLYGVKRTLDL 326
           GV +    G     + 
Sbjct: 310 GVHVLASDGSVMPFER 325


>UniRef50_B0KL72 Thiamine-monophosphate kinase n=13 Tax=Pseudomonadaceae
           RepID=B0KL72_PSEPG
          Length = 322

 Score =  212 bits (540), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 67/314 (21%), Positives = 109/314 (34%), Gaps = 24/314 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLV-AEGDRLAFSTDSYVIDPLFF---PGGNI 72
           +LIN  F  A               D A L    G++LA STD+ V    F        +
Sbjct: 5   ELINHYFAAAPCAQGGEGVALGIGDDCALLDLPPGEQLAVSTDTLVAGVHFPVACDPLLL 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ ++   A+D+A  GA     +    L   +    L A    ++  A+   ++++ GDT
Sbjct: 65  GQRSLAVAASDLAAMGATAIGFTLALTLP-DVGPGWLSAYADGLSRMAQRCRMSLIGGDT 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I     G +P            GD+L V G+LG     +  +  +   
Sbjct: 124 TRGP------LSITVTVFGRVPVGQALRRSGARPGDLLCVGGSLGKAAGALPLVLGEREA 177

Query: 193 DGELVSDC-----AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEA 247
                        + +  L           A  D +  G+ A     A A G  +E++ A
Sbjct: 178 PAAQAEPLLAHYWSPMPQLTLGALLRGRATAALDISD-GLLADCGHIAKASGVALEVNLA 236

Query: 248 ALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
            +PV PA+      E     AL   ++  L   +   A   +     +     +   IG 
Sbjct: 237 QVPVSPALEAFLGREAAVRAALTGGDDYVLAFTLPPEALAPL-----AAFDTIEVHTIGR 291

Query: 306 VVERKGVRLAGLYG 319
           V+E +GV L    G
Sbjct: 292 VLEGQGVTLRDAQG 305


>UniRef50_Q1YU39 Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium
           HTCC2207 RepID=Q1YU39_9GAMM
          Length = 305

 Score =  211 bits (539), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 65/316 (20%), Positives = 109/316 (34%), Gaps = 24/316 (7%)

Query: 31  WLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNIGKLAICGTANDVAVS 87
            L   +D A L+    V  G +L  ++D+ V    F        I   A+C   +D+A  
Sbjct: 2   ALGIGDDAALLN----VRPGQQLVMASDTLVSSIHFPESATPRQIATRALCVNLSDMAAM 57

Query: 88  GAIPRYLSCGFILEEG-LPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFIN 146
           GA PR+ +    L       E L      +   A    +A+V GDT          L + 
Sbjct: 58  GAEPRWFTLALTLPRDKAKAEWLAEFSVGLGHIANQYNLALVGGDTTSGP------LTLT 111

Query: 147 TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG---LDGELVSDCAVL 203
              +G +P +        + GD + V+GTLGD  A +     +         L+      
Sbjct: 112 LTLVGEVPVDKALTRGGASIGDSVFVTGTLGDGAAGLKIASNKNSNCIDSDRLLQRFYSP 171

Query: 204 TPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLG 263
            P IQ    +  + +       G+ A +     A      +    LP+   V+ +  L  
Sbjct: 172 QPQIQAGLKLRSIASACIDISDGLLADLGHICKASDVSAVIKAEQLPIAADVQQLSALDA 231

Query: 264 LDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER----KGVRLAGLY 318
           L   L+  ++ +L   V       V   +    L  DA+ IG +         V +    
Sbjct: 232 LQWALSGGDDYQLCFTVATGQLPTVEGWIEKGEL--DASRIGFIEAARDSINRVSVVDKN 289

Query: 319 GVKRTLDLPHAEPLPR 334
            +  T++ P      R
Sbjct: 290 NLPLTIEKPGYNHFGR 305


>UniRef50_Q3ARA0 Thiamine-monophosphate kinase n=11 Tax=Chlorobiaceae
           RepID=Q3ARA0_CHLCH
          Length = 369

 Score =  211 bits (539), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 71/355 (20%), Positives = 125/355 (35%), Gaps = 49/355 (13%)

Query: 10  SGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRL-AFSTDSYVIDPLFF- 67
           +G   +   I  L     AN            D A +      +   +TD  V    F  
Sbjct: 4   NGEFTLIDTIAHLVQPTLANAP--TLLQGIGDDCAIMQPTAGMVEVATTDLLVESVHFDL 61

Query: 68  ---PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAG 124
              P  ++G  AI    +D+    A+PRY      L      + ++ +   M   A+A G
Sbjct: 62  LTTPLSHLGSKAISVNVSDICAMNALPRYALVSLALPPTFSKKMVEELYGGMVHAAQAYG 121

Query: 125 IAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL 184
           IAI  GDT   + G    L I+   +G                D+L V+GTLG   A + 
Sbjct: 122 IAIAGGDTSASRSG----LMISITAIGEALPTQLTRRSGAQLDDLLCVTGTLGGSMAGLK 177

Query: 185 NLREQ---------------------LGLDGELVSDCAVLTPLIQTLRDIPGV----KAL 219
            L  +                     L    EL+    + T  +  +R    +     A+
Sbjct: 178 LLMREKEIMLEHLRNNEPVNRNLLADLDEYRELMQRHLLPTARLDVVRLFHRLGIQPTAM 237

Query: 220 RDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNF----ANEGKL 275
            D +  G+++ V        CG  L E+ +P+    R + + +  + L +      E +L
Sbjct: 238 IDISD-GLSSEVQHICRHSNCGALLHESRIPIHATTRQLADEMQEEPLTWALTGGEEYQL 296

Query: 276 VIAVERNAAEQVLAALHSHPLGKDAALIGEVVE-RKGVRLAGLYGVKRTLDLPHA 329
           +  +     +Q+          +D  +IG +    +G+ L  ++G++  L   H 
Sbjct: 297 LFTLPEATYQQLAHE-------RDIHVIGTITPTNEGMVLEEMFGIRIDLTTIHG 344


>UniRef50_B6BWK7 Thiamine-monophosphate kinase n=1 Tax=beta proteobacterium KB13
           RepID=B6BWK7_9PROT
          Length = 316

 Score =  211 bits (539), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 52/308 (16%), Positives = 105/308 (34%), Gaps = 28/308 (9%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGGNIG 73
            LI   F     +  L   +D A +     +   + +A S D+  I   F        +G
Sbjct: 5   DLIKKYFNFTSKHALLGIGDDAALI----PLNNNEFMAISMDTLNIGHHFTEDSDPYYLG 60

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             ++    +D+   G  PRY      L + L +  +      +   A+   I IV GDT 
Sbjct: 61  WKSLAVNVSDIVSMGGQPRYALLSISL-KNLDVNWIGKFTKGIKACAKKYNIEIVGGDTN 119

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI----LNLREQ 189
                      I+ A MG + +            D + V+  +G          L  + +
Sbjct: 120 KGSTS------ISIAIMGNVSSKNVLKRSGAIPEDEIWVTNEVGYAALHFNQHSLLPKYK 173

Query: 190 LGLDGELVSDCA----VLTPLIQTLRDIPG-VKALRDATRGGVNAVVHEFAAACGCGIEL 244
             +   L   C        P ++ ++D    + +  D +  G+   +     +   G ++
Sbjct: 174 KSISNCLKKRCQEEFFKPQPPLEFIQDTKSMINSAIDLSD-GLVGDLKHILNSSSVGAKI 232

Query: 245 SEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
               +P+    RG  +     A+    + ++++        ++   L  H L    A+IG
Sbjct: 233 EINEIPMHKWFRGNNQY--ELAMCGGEDYQILMTASHKHHNKIQNLLKKHSL--KGAMIG 288

Query: 305 EVVERKGV 312
            + + K +
Sbjct: 289 IITKDKKI 296


>UniRef50_D2MI54 Thiamine-monophosphate kinase (Fragment) n=1 Tax=Candidatus
           Poribacteria sp. WGA-A3 RepID=D2MI54_9BACT
          Length = 278

 Score =  211 bits (537), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 59/271 (21%), Positives = 103/271 (38%), Gaps = 24/271 (8%)

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A     +DVA  G  P Y+     +    P + ++A+   + +      + ++ G
Sbjct: 4   DVGWRAGVANLSDVAAMGGTPLYVLVSIAVPVRTPPKNIRALYRGLQDACAPCNVELIGG 63

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           DT          +F++   +G++ AN          GD L V+GT+GD  A +  L+   
Sbjct: 64  DTSSSPS----HVFLSLTIVGSVRANRALTRHGAEVGDRLYVTGTVGDANAGLRILQSHS 119

Query: 191 G---------LDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAAC 238
                      +  L+      TP IQ    L D     A  D +  G+++ V       
Sbjct: 120 NNLRRFSPSAAEKFLIRRHRRPTPRIQVGQLLVDRNLAHAAIDLSD-GLSSDVGHVCEES 178

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSH 294
             G E+   ALP+   +R   +   LD     L    + +L+        ++VL  L S 
Sbjct: 179 QVGAEIRGEALPLSSPLRAFAKRHDLDPMELALQGGEDYELLFIAPAKHHQKVL--LVSE 236

Query: 295 PLGKDAALIGEVVERK-GVRLAGLYGVKRTL 324
                 + IGE+  +  G +L    G  + L
Sbjct: 237 QTKVPISCIGEIKPKTFGQQLELPGGRIQRL 267


>UniRef50_A8MDD6 AIR synthase related protein domain protein n=1 Tax=Caldivirga
           maquilingensis IC-167 RepID=A8MDD6_CALMQ
          Length = 337

 Score =  210 bits (536), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 68/318 (21%), Positives = 118/318 (37%), Gaps = 21/318 (6%)

Query: 13  QAMQQLINSLFMEAFA-NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           +     I     +                 D A +      +A  TD     P+      
Sbjct: 3   KFSNAFIEREVFKMLGVRDNSVTLGPGIGEDAAVIRINNSYMAVHTD-----PVTGSSNL 57

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G LA+   AND+A  G  PR+     IL        +  ++  + +       ++V G 
Sbjct: 58  LGWLAVHVAANDIATRGIRPRWFLVTLILPVDYGENDVVNIMRQINDALIEINASLVGGH 117

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T+     AV +    T  +G    +       L  GDV++++         +L    +  
Sbjct: 118 TEKSD--AVTRPIAVTTAIGI--GSRFIRTGGLRTGDVIVMTKYAALEATAVLVSDFRGR 173

Query: 192 L-----DGELVSDCAVLTP---LIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
           L     +GE     ++      +   L       ++ D T GGV   + E A + G  I 
Sbjct: 174 LMNVLSEGEFKEATSLYRMVSVVNDALAAAEYATSMHDPTEGGVLQGLLEMAYSSGKLII 233

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           ++E  +PV P  R V     L+ L   + G L+I V  N A +++  L    +G +A++I
Sbjct: 234 INEDNIPVLPVTRRVLNAFNLNPLTVLSSGSLLIGVGENDAAKLIGKLR--DMGINASII 291

Query: 304 GEVVER-KGVRLAGLYGV 320
           G+V +   GV + G  G 
Sbjct: 292 GKVTDGEPGVVVKGRSGE 309


>UniRef50_Q21F21 Thiamine-monophosphate kinase n=1 Tax=Saccharophagus degradans 2-40
           RepID=Q21F21_SACD2
          Length = 334

 Score =  210 bits (535), Expect = 6e-53,   Method: Composition-based stats.
 Identities = 66/328 (20%), Positives = 114/328 (34%), Gaps = 43/328 (13%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLF---FPGGNI 72
            LI   F     +P +         D A L +     +A S D+ V    F       +I
Sbjct: 5   DLIKQYFRNV--SPVVEGTTLGNGDDCALLQLKPNQTMAVSVDTLVEGVHFPCGASANDI 62

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
            + A+    +D+A   A PR+++    L +    + L A    +     A    ++ GDT
Sbjct: 63  AQRALRTALSDLAAMAATPRWVTLALTLPQHNS-DWLSAFSEGLRADLHAFNCELIGGDT 121

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ--- 189
                     L I+   MG +             GD + V+ TLG+  A++L +  +   
Sbjct: 122 TRG------ALTISVQVMGVVENYPALTRAGAKVGDGIFVTHTLGNGAASLLQVLGKLQS 175

Query: 190 LGLDGELVSDCAVLTPLIQTL-----RDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
           L L   L S+   L    +       +      +  D +  G+ A +     A G G ++
Sbjct: 176 LALPNALCSELDDLFYRPELAFYVAQQLHAVATSAIDISD-GLVADLKHICTASGVGAKV 234

Query: 245 SEAALPVKPAVRGVC----------------ELLGLDALNFANEGKLVIAVERNAAEQVL 288
           + A LP     + +                 +LL   AL   ++ +L      +A  ++ 
Sbjct: 235 NVAQLPYSATAKSLAKGIENTALNSERLTAQQLLQQWALYGGDDYQLCFTAPAHAVAEL- 293

Query: 289 AALHSHPLGKDAALIGEVVERKGVRLAG 316
                      A  IG VV  +GV+L  
Sbjct: 294 ----KEQTPLAATQIGVVVAEQGVQLHN 317


>UniRef50_C0QQC1 Thiamine-monophosphate kinase n=2 Tax=Hydrogenothermaceae
           RepID=C0QQC1_PERMH
          Length = 317

 Score =  210 bits (535), Expect = 6e-53,   Method: Composition-based stats.
 Identities = 50/327 (15%), Positives = 104/327 (31%), Gaps = 37/327 (11%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP----GGNIG 73
           LI+ L      +    +       D A +  +G  + F+ D  + +  F        ++G
Sbjct: 11  LIDRLTKILRIDDP--DVVVGFGDDCACVNLDGKLMLFTGDIQLENHHFIKGKIKPEDLG 68

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
              +    +D+   G  PR+      + E      ++ V   M +     G +++ G+T 
Sbjct: 69  WKLVSINVSDIVACGGKPRWGFISIGIPESTEYSFIEGVYKGMNDALDRYGFSVIGGNTT 128

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL----REQ 189
             +     ++ ++   +G               G+V+L+SG  G   A +  L       
Sbjct: 129 SSE-----EIILDLFLVGETE--RFVPRGGAEEGEVILLSGFTGCSRAGLELLLMDRESY 181

Query: 190 LGLDGELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
              +  L+                    ++  D +  G+   +       G  + + +  
Sbjct: 182 EDFEMRLIEKHTRPEARYDLQNLIQRYARSCIDISD-GLVGDLSHIQKMSGVKLVIEKDK 240

Query: 249 LPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           LPV P +   C+  G D     L    + +LV  V +   E+                IG
Sbjct: 241 LPVDPDLERFCKKYGKDIYDYILYGGEDYQLVFTVNKQDTEKFKDCFK----------IG 290

Query: 305 EVVERKGVRLAGLYG----VKRTLDLP 327
              +  G+ +    G     +R  +  
Sbjct: 291 YTEKGSGIFIKDEKGLKPLKERGFEHL 317


>UniRef50_A8VUM5 Beta-lactamase domain protein n=1 Tax=Bacillus selenitireducens
           MLS10 RepID=A8VUM5_9BACI
          Length = 332

 Score =  210 bits (535), Expect = 6e-53,   Method: Composition-based stats.
 Identities = 66/320 (20%), Positives = 114/320 (35%), Gaps = 25/320 (7%)

Query: 28  ANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTAND 83
            +  L   +D A +     V +G     + D+ V D  F        +IG  A+    +D
Sbjct: 19  EDVELGIGDDAAIVR----VPDGYDQVLAVDTMVEDVHFSRATMAPEDIGYKALAVNISD 74

Query: 84  VAVSGAIPRYLSCGFILEE-GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDK 142
           +A  GA+P+       + + G P E  + +   + E A   G+ ++ GDT        DK
Sbjct: 75  LAAMGAVPKQYLVSLAVPKQGWPDEETRRIYAGLEEAAALYGMDLIGGDTVST----ADK 130

Query: 143 LFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG-------LDGE 195
           L I+    G +  ++         GDV+ V+G LG   A +  L +Q            +
Sbjct: 131 LVISVTVTGIVETSVRLLRANARPGDVIAVTGPLGASLAGLDLLLDQTNGVPVPEMDQDQ 190

Query: 196 LVSDCAVLTPLIQTLRDIP--GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
           L+       P ++  R     G++A  +    G++    E A A G  + L    +P   
Sbjct: 191 LIRSHQRPVPQVKAGRLFAELGIRAALNDISDGISREAKEIAEASGVRMVLDWKRIPKPD 250

Query: 254 AVRGVCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGV 312
            +    E    D  L+   E +LV          V   L +   G   + +G V   +  
Sbjct: 251 ILALFDEEKQKDWVLHGGEEFQLVCVFSGKHWRDVC--LLAEQHGITISPVGMVEAGEPA 308

Query: 313 RLAGLYGVKRTLDLPHAEPL 332
            +        TL     +  
Sbjct: 309 VILIDGQESETLTKSGYDHF 328


>UniRef50_UPI0000E87BC8 Thiamine-monophosphate kinase n=1 Tax=Methylophilales bacterium
           HTCC2181 RepID=UPI0000E87BC8
          Length = 314

 Score =  210 bits (535), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 59/312 (18%), Positives = 111/312 (35%), Gaps = 26/312 (8%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI---G 73
            LIN  F +  +   L   +D A L+        +    S D+  +D  FF   NI   G
Sbjct: 6   SLINKYFNQKSSTAPLGIGDDGALLE----KNSQNYYVLSQDTLNVDSHFFRDTNIKYLG 61

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
              +    +D+   G  P++       EE      LK   + + + A   G+ ++ GDT 
Sbjct: 62  WKTLAVNVSDILAMGGNPKFALLSISTEEAND-SWLKKFSSGLFDCANQYGVELIGGDTS 120

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
                    L +    +G +            A + + +SG LG       +  + L L 
Sbjct: 121 RGS------LSVTITIIGEVKKKYVLRRDGANAEEDIWISGELGLASLGFAHQIKTLSLP 174

Query: 194 GELVSD----CAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
           G +           TP+I  +  I  +  +  D +  G+   +         G ++    
Sbjct: 175 GHISKKALLALHKPTPIIIDMSKINHLFTSAIDISD-GLVPDIQHILNKSNIGADIFCEH 233

Query: 249 LPVKPAVRGVCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
           LPV      + E  G D AL    + +L +   ++  +++     +       ++IG+  
Sbjct: 234 LPVP---LWIKENDGYDFALYGGEDYQLALTSPKSNRKKIEKI--AAQNNLQLSVIGKTN 288

Query: 308 ERKGVRLAGLYG 319
             K ++L  + G
Sbjct: 289 TSKALKLYDVNG 300


>UniRef50_B6YTL7 Thiamine monophosphate kinase n=2 Tax=Thermococcus
           RepID=B6YTL7_THEON
          Length = 311

 Score =  210 bits (535), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 63/327 (19%), Positives = 108/327 (33%), Gaps = 35/327 (10%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYV---IDPLFFPGGN 71
           M++ I  LFM+        + +     D   L    + L  + D  V     P       
Sbjct: 1   MEREIIELFMKYLK----KQGDLPLGDDAGALRIGDEWLVATNDMLVGKTDVPDIMTPEQ 56

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  A+    +D+A  GA P        +  G     L+ V   +        I +++ D
Sbjct: 57  VGFKAVTMNVSDIAAMGARPIGFLFSLGVPRGFDGLYLEGVAKGIGNALEFYEIPVLSAD 116

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T        D L I+   +G               GD++ ++G +G   A +L  +  L 
Sbjct: 117 TN-----EADDLIIDGIALGRTR--HLLTRSGAKPGDLVCITGDIGRPLAGLLVWKNDLD 169

Query: 192 L-----DGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
           +     +            + + ++      A  D +  G+   +H  A   G  IE+  
Sbjct: 170 VSLSTKEILYEKLLEPRARVKEGIKIGNYANAAIDISD-GLAKELHLVAEMSGVRIEVDA 228

Query: 247 AALPVKPAVRGVCELLGLDALN----FANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
           + LP+   V  V ELL  D L        E +LV  +     E++           D  +
Sbjct: 229 SKLPIMEEVFEVAELLRRDPLEIALASGEEFELVFTIPPKYTEEL---------SFDFTV 279

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPHA 329
           IG V +  GV +            P  
Sbjct: 280 IGTVHKGAGVFITTEEKRMEV--PPIG 304


>UniRef50_C7NS45 AIR synthase related protein domain protein n=1 Tax=Halorhabdus
           utahensis DSM 12940 RepID=C7NS45_HALUD
          Length = 345

 Score =  209 bits (534), Expect = 8e-53,   Method: Composition-based stats.
 Identities = 81/334 (24%), Positives = 125/334 (37%), Gaps = 22/334 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLA-EQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+A ++  +                + Q  +D       G  LA +TD   I P      
Sbjct: 7   GKADREFFDEYIYPRLGADRDDVRLQPQHGVDFGVADVGGQALAMATDPVFIVPAAG-FE 65

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
                A     +DVAVSG  P YLS  F L   +  E  + V  +  + A   G +IVTG
Sbjct: 66  RAAWFAFHILFSDVAVSGLDPAYLSVDFNLPPEITDEQFETVWETFDQEAAELGASIVTG 125

Query: 131 DTKVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
            T        +   +     +     +          GD ++V+         +L++   
Sbjct: 126 HTGRY--AGCNYPMVGGATTVATGDFDDLVTPDGARPGDRVIVTKGPAIEATGLLSVHFD 183

Query: 190 LGLDGELVSDC----------AVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
             +DGE+ +D                          V A+ DAT GGV   + E A +  
Sbjct: 184 SLMDGEVPADEIQAAKDRFYDMSPIQEAMVASAAGPVTAMHDATEGGVYGGLFEMARSAD 243

Query: 240 CGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            G E+    +PV+P V   C+   +D     +EG L+  V+ + A  VL+AL S   G  
Sbjct: 244 VGFEIERDRIPVQPGVEAACDFFDIDPWISISEGTLLATVDPDGASDVLSALKSE--GIP 301

Query: 300 AALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
           AA  G VVE  G+ + G     + +D P  +P  
Sbjct: 302 AADAGRVVEGSGLTVDG-----QAVDHPGKDPYW 330


>UniRef50_A3DLS7 AIR synthase related protein domain protein n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DLS7_STAMF
          Length = 355

 Score =  209 bits (534), Expect = 9e-53,   Method: Composition-based stats.
 Identities = 64/336 (19%), Positives = 126/336 (37%), Gaps = 21/336 (6%)

Query: 10  SGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPG 69
            GG+   + ++ +                   D A +  +   L   +D     P+    
Sbjct: 22  EGGKPSWEFLSEMLSILPTMDPDLIVGPSIGEDAAIIRFKDGFLIVHSD-----PITAAT 76

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
             IG LA+   AND+AV GA PR+     +L    P+E ++++   +    R+ G  ++ 
Sbjct: 77  RRIGWLAVHIVANDIAVRGATPRWFLPVILLPPKYPVEQIESIFEDIGLATRSLGATVIG 136

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ 189
           G T+      + +  I+   +G    +     +    GD + + G +G  GA+++    +
Sbjct: 137 GHTEFTP--GIPRPIISMTAIGYSM-DKVVLTRNARPGDKIFIIGRVGGEGASVIAWDFE 193

Query: 190 -----LGLDGELVSDCAVLTPLIQ----TLRDIPGVKALRDATRGGVNAVVHEFAAACGC 240
                 G+  ++++        I      L     V ++ D T GG+   + E A A   
Sbjct: 194 DLLLRKGISRDIIAKAKEYFTGISVVDKALLIRDYVNSMHDPTEGGLLQGLREVAKASNT 253

Query: 241 GIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
            I L    + + P V+ +   L LD L   + G L+ +V +    QV   L         
Sbjct: 254 RIILDADKIILDPVVKEITSALKLDPLKILSSGVLIASVPKENTRQVEDLLQEKEY--KY 311

Query: 301 ALIGEVVE--RKGVRLAGLYGVKRTLDLPHAEPLPR 334
           ++ G + E  + G  +    G    +     + + +
Sbjct: 312 SIAGYISEYVKGGELIVEQNGKTIRIIEDVVDEIYK 347


>UniRef50_A0NME7 Thiamine-monophosphate kinase n=2 Tax=Labrenzia RepID=A0NME7_9RHOB
          Length = 332

 Score =  209 bits (533), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 63/320 (19%), Positives = 111/320 (34%), Gaps = 29/320 (9%)

Query: 17  QLINSLFMEAFANPW-LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNI 72
           +LI   F     +P  L   +D A L       +G  L  + D    D  FF       I
Sbjct: 10  ELIRRFFAPLAKDPGSLGLTDDAAVL----TPHQGYDLVLTKDVLAADIHFFAEDAPEAI 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
              A+    +D+A  GA PR    G  L     ++ L+     +A    A    +  GDT
Sbjct: 66  AAKALRVNLSDLAAKGARPRGYLMGLSLPSDWTVDWLERFCNGLAADQAAYDFHLYGGDT 125

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ--- 189
                   + L ++   +G +             GD+L V+GT+GD  A +         
Sbjct: 126 VRS----GNGLQVSITAIGEVETGKAVRRSGAQPGDLLFVTGTIGDAAAGLQARLNPDFC 181

Query: 190 ------LGLDGELVSDCAVLTPLIQ-TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
                    +G ++    +  P  +          A  D +  G+ A     A A    +
Sbjct: 182 RDHDLTESEEGHILDRYLLPRPCTRLAGAVADYASAAMDVSD-GLIADCAHMAKASALEL 240

Query: 243 ELSEAALPVKPAVRGVCELLGLD---ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            +    +P+  A+  +      D    LN  ++ ++++AV +  ++ +     +H  G  
Sbjct: 241 TIDLDLVPLSQALTHLKIKAPEDFARCLNGGDDYEILMAVPQERSDTLRRV--AHLAGCP 298

Query: 300 AALIGEVVERK-GVRLAGLY 318
              IG     + G+RL    
Sbjct: 299 VTQIGYARAGEAGLRLVDAG 318


>UniRef50_A4YFC4 AIR synthase related protein domain protein n=3 Tax=Sulfolobaceae
           RepID=A4YFC4_METS5
          Length = 332

 Score =  209 bits (533), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 70/336 (20%), Positives = 124/336 (36%), Gaps = 29/336 (8%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQA------RLDLAQLVAEGDRLAFSTDSYVIDPLFFP 68
           M   I+    +    P L ++ D+        +D   +      L   TD   I P F  
Sbjct: 1   MLGKIDRKVFDEVIYPHLGKRLDEVIVPPLTGVDTGAIDLGDRVLVVKTDPVFIVPQFG- 59

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
                  A+   A+DV  SG  PRY      L   +  E  + +   + E     G+ +V
Sbjct: 60  MKKASWFAVHILASDVMTSGIPPRYALLDLNLPPSMTDEEFREMWVGIHEALLEIGVMVV 119

Query: 129 TGDTKVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR 187
            G T   +   V+   +     +G            +  GD ++V+         +L   
Sbjct: 120 GGHTGRYE--GVNYPMVGGFTMIGIGEKEKLGHPSKVKPGDYVIVTKGPAIEATGLLTNL 177

Query: 188 EQLGLDGELVSDCAV----LTPLIQTLRD-----IPGVKALRDATRGGVNAVVHEFAAAC 238
                   + SD       +   +   +D       G+  + DAT GG+   + E +   
Sbjct: 178 YPEFFRERMRSDLFKEALDMYWKMSCWKDGLIASQVGIHMMHDATEGGLWNALVEISEVT 237

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
           G  I L    L + PAVR V  ++G+D  +  +EG +VI  ++   ++    L +   G 
Sbjct: 238 GKRINLVGERLFINPAVREVTRIVGIDPFSSISEGTMVIVTDKEKVKE--ELLRN---GI 292

Query: 299 DAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           +A ++G V   +GV + G     + ++ P  +P  R
Sbjct: 293 EAEIVGRVESGEGVYVDG-----KRIEKPSEDPFWR 323


>UniRef50_Q2S9S1 Thiamine-monophosphate kinase n=1 Tax=Hahella chejuensis KCTC 2396
           RepID=Q2S9S1_HAHCH
          Length = 325

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 70/328 (21%), Positives = 125/328 (38%), Gaps = 25/328 (7%)

Query: 17  QLINSLFMEAFAN-PWLAEQ-EDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGN 71
           +LI+  F   FAN P +    E     D A L     RL  STD+ V    F        
Sbjct: 5   ELISRYFHAPFANFPNVGRLIETGIGDDCAVLTPLSGRLVISTDTCVSGAHFPVDTSAEM 64

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +   ++  + +D+A  GA P   +    L   +    L+A  + + E+A A  I ++ GD
Sbjct: 65  VAARSLGSSVSDLAAMGAEPVGFTLALTLP-TINEAWLQAFGSQLYESALAWRIPLIGGD 123

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T          L +    +G +  +          G+ + VSG+LGD  A +  L     
Sbjct: 124 TTKGP------LAVTVTVLGRV-QDQCLYRHGAAPGEDVWVSGSLGDAAAALSLLGRPDA 176

Query: 192 ----LDGELVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSE 246
               ++  L    A   P ++    + G+  A  D +  G+ A +    +A  CG  + E
Sbjct: 177 SLTPIERWLYQRYASPQPRLRLGSMLRGIATAAIDISD-GLIADLAHICSASNCGALIEE 235

Query: 247 AALPVKPAVRG-VCELLGLD-ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
            A+P+ PA+     +   L+ AL   ++ +L     ++  +     + S       + IG
Sbjct: 236 GAIPLSPALLATFSKEEALNCALEGGDDYELCFTAPQSTRD----LIQSLSADVALSRIG 291

Query: 305 EVVERKGVRLAGLYGVKRTLDLPHAEPL 332
            + +  GV +       R +     +  
Sbjct: 292 TLRKESGVSMQRRGEEIRLMTKGGYDHF 319


>UniRef50_Q8D289 ThiL protein n=2 Tax=cellular organisms RepID=Q8D289_WIGBR
          Length = 329

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 51/319 (15%), Positives = 117/319 (36%), Gaps = 32/319 (10%)

Query: 16  QQLINSLFMEAFA---NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---G 69
             +I + F ++     N  +   +D A L+    + +      +TD+ V++  F      
Sbjct: 13  WNIIKNFFKKSKNINKNVAVGIGDDCAVLN----IKKDSFFVITTDTLVLNTHFLDSIKP 68

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            ++G  +     +D+A  GA+P+++     + +      + +    + +      + ++ 
Sbjct: 69  KDLGYKSASVNLSDLASMGAVPKWILLSITIPK-FNKSWISSYSEGLFDNLNYFNVKLIG 127

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIH-WGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
           GD           L I     G IP              D++ ++GTLGD  A +  L +
Sbjct: 128 GDLNKGP------LSITITACGTIPKKKIKMTRSGAKINDLIYITGTLGDSAAGLAILMK 181

Query: 189 QLGLDGE-----LVSDCAVLTPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
            L ++       L+      +P I+  +       +  D +  G+   + +  +   CG 
Sbjct: 182 NLKINNTNSKKYLLKRHFRPSPRIREGIMLSNFANSACDISD-GILIDLKKILSCSNCGA 240

Query: 243 ELSEAALPVKPAVR---GVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            +    +P+   +       + +   ALN   + +L + V      +  + +  +     
Sbjct: 241 NIYIDRIPMSNHLLNNVEYKKAINF-ALNGGEDYELCVTVPIKKYYEFNSMIKKNK--IF 297

Query: 300 AALIGEVVERK-GVRLAGL 317
              IG +  +K G++L G 
Sbjct: 298 ITYIGNICSKKVGLKLIGD 316


>UniRef50_Q3A8K1 Thiamine-monophosphate kinase n=2 Tax=Desulfuromonadales
           RepID=Q3A8K1_PELCD
          Length = 329

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 75/320 (23%), Positives = 116/320 (36%), Gaps = 22/320 (6%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFPGGN----I 72
            I  +   A +   +         D A L +  G RL  + D  +    F         +
Sbjct: 11  FIKRIRAAAASGEGVCH---SIGDDCAVLELPPGQRLLTTKDLLIEGVHFQRAWTDSRSL 67

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ ++    +D+A  G  PR+L  G  +     +E L+  +    E   A G  +V GDT
Sbjct: 68  GRKSVSVNVSDIAAMGGRPRHLYLGLGVPADFSVEELQLFMDGFLEAVTAYGACLVGGDT 127

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I+    G++ A           G ++ VSGTLGD    +  L +    
Sbjct: 128 CRSPG----PLLISVTAEGSVAAGREVRRAGAGIGQIIYVSGTLGDSALALQQLGKGEVP 183

Query: 193 DGELVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAAL 249
           D  L S     T  +   Q L       A+ D +  GV A +     A   G  L E+ L
Sbjct: 184 DSFLASRHHDPTARVALGQALAQAGLATAMIDISD-GVLADLGHILKASSVGALLEESLL 242

Query: 250 PVKPAVRGV---CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           P+  A R V      L   AL+   + +L+  V      +V A   +  L      IG +
Sbjct: 243 PLSGAFRAVLQHAPHLLQLALSGGEDYELLFTVAPEREAEVDAL--ARTLALPLTRIGVI 300

Query: 307 V-ERKGVRLAGLYGVKRTLD 325
               +G+RL    G  R  +
Sbjct: 301 TSADEGLRLRAADGSLRPAE 320


>UniRef50_C9LRA0 Thiamine-phosphate kinase n=1 Tax=Dialister invisus DSM 15470
           RepID=C9LRA0_9FIRM
          Length = 329

 Score =  209 bits (532), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 60/326 (18%), Positives = 109/326 (33%), Gaps = 28/326 (8%)

Query: 19  INSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGK 74
           I    +       L   +D A      +   G     STD+ V    F        + G 
Sbjct: 18  IAHDLIYRPELVKLGTGDDGAVF----MTPCGYDEVISTDTMVEGIHFTKRTMSAADTGY 73

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
                  +D+A  GA P        L   L +  +++    + E  R   + ++ GD   
Sbjct: 74  HLCAVNFSDMAAMGAEPVSFVISAALPGDLSITWIESCYDGIRECCREYSVNLLGGDIT- 132

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
              G+   + +    +G +P N          GD++ V+GTLGD  A +  L +    + 
Sbjct: 133 ---GSKQGVILTGTIVGIVPENQAVKRSGAKEGDIVFVTGTLGDSSAGLSILLDGKKEEY 189

Query: 195 ELVS-DCAVLTPLIQTLRDIP--GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
            +++       P I   R +   G  +L D +  G++  ++E  +A    IEL +  +P+
Sbjct: 190 PMLAIRHQRPKPQIDFGRILRESGASSLNDVSD-GLSREINEITSASRVTIELEKERIPL 248

Query: 252 KPAVRGVCELLGLDALN----FANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
              +       G D          + +LV  + +   E +               IG V 
Sbjct: 249 SDELCRWGRDCGKDPFCFAINGGEDYELVGTISKKNWEYIKDI-------DGVTGIGHVT 301

Query: 308 -ERKGVRLAGLYGVKRTLDLPHAEPL 332
              KG          + L +   +  
Sbjct: 302 KAGKGQVFLKDKNSIKLLTIAGYDHF 327


>UniRef50_D1C5Z5 AIR synthase related protein domain protein n=7 Tax=Chloroflexi
           RepID=D1C5Z5_SPHTD
          Length = 359

 Score =  208 bits (531), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 78/340 (22%), Positives = 132/340 (38%), Gaps = 24/340 (7%)

Query: 12  GQAMQQLINSLFMEAFANPWLAE-QEDQARLDLAQLVAEGDR-LAFSTDSYVIDPLFFPG 69
           G+   ++   +                Q  +D+  +   G R +A +TD + I P +   
Sbjct: 14  GKISPEVFEQVIKPRLGRHRPEVLVGPQHGVDVGIIDIGGGRVMAVTTDPFFIVPQYG-W 72

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
                 A+   A+D A SG  P Y      L   +  E L+A+  ++  T +  G+AIVT
Sbjct: 73  ERAAWFAVHILASDAATSGLPPTYFVVDLNLPRNITSEGLEALWHAVDATCKEIGMAIVT 132

Query: 130 GDTKVVQRGAVDKLFINTAGMGAI-PANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
           G T        D   +  A + A+   + +        GD ++V+         +  +  
Sbjct: 133 GHTARYD--GTDYPMVGGAMVMAVGERDRYVTPTMARVGDAVIVTKGAAIEATGLFGVTF 190

Query: 189 QLGLDGELVSDCAVLTP--------------LIQTLRDIPGVKALRDATRGGVNAVVHEF 234
              +      + A                   ++      GV A+ DAT GGV   ++E 
Sbjct: 191 PDRIAAAYGQEIARQAEETFYQMSVVKDAMTAVEVGVRDAGVTAMHDATEGGVWGGLYEI 250

Query: 235 AAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSH 294
           A A G G+ + + A+ V PA + VC+L G++     +EG L+I      A  VL  L   
Sbjct: 251 AVASGVGMVVEQNAIVVSPAAQAVCDLFGMNPYAAISEGTLIITCRPEKAGAVLTRLEDA 310

Query: 295 PLGKDAALIGEVV-ERKGVRLAGLYGVKRTLDLPHAEPLP 333
             G  A  +GE+    +G+RL    G +  L+ P  +P  
Sbjct: 311 --GIAATQVGEITPPEEGIRLV-RDGREEPLEHPRVDPFW 347


>UniRef50_B5JUN1 Thiamine-monophosphate kinase n=1 Tax=gamma proteobacterium
           HTCC5015 RepID=B5JUN1_9GAMM
          Length = 305

 Score =  208 bits (529), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 57/296 (19%), Positives = 109/296 (36%), Gaps = 18/296 (6%)

Query: 28  ANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGKLAICGTANDV 84
           ++  L   +D A L        G RLA S+D+ +    F        +G  A+    +D+
Sbjct: 9   SDVQLGPGDDAAILQA----PAGYRLATSSDTLIAGRHFPENTVPEAVGHKALAVNLSDL 64

Query: 85  AVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLF 144
           A  GA P ++S    L E   +  L+   +     A   G+A++ GDT          L 
Sbjct: 65  AAMGAKPAWVSLALTLPEASEV-WLRGFASGFGALAAEYGVALIGGDTTRGP------LS 117

Query: 145 INTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLT 204
           +     G +P +          G+ + VSG LG     +  + +   L  +         
Sbjct: 118 VTLTVTGFLPESQALLRSGAQIGESVYVSGRLGAAAQELGQVLQGGSLSPDQRRHLDYPQ 177

Query: 205 PLIQTLRDI-PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLG 263
           P ++  + + P   +  D +  G+ +     AAA    +++  + LP+  ++  +     
Sbjct: 178 PRVELGQQLLPVASSAMDLSD-GLLSDAAHLAAASELAVDIDLSRLPLAESLASLPREEA 236

Query: 264 LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYG 319
               +  ++ +L+       + ++ A   S  LG     +G   E  GV      G
Sbjct: 237 WALASAGDDYELLFTAPNVESPRLEAL--SQTLGLPLTRVGRTREGDGVHCFERDG 290


>UniRef50_C1ZKV1 Thiamine-monophosphate kinase n=1 Tax=Planctomyces limnophilus DSM
           3776 RepID=C1ZKV1_PLALI
          Length = 320

 Score =  208 bits (529), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 60/332 (18%), Positives = 107/332 (32%), Gaps = 42/332 (12%)

Query: 10  SGGQAMQQ----LINSLFMEAFA--NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVID 63
           +GG+   +    LI  +   A       L   +D A L       E      +TD  +  
Sbjct: 4   TGGRMTFRPEFALIERIRKAAGGSSRVLLGIGDDAAGLG----SREDRETLVATDMLLDG 59

Query: 64  PLFF----PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAET 119
             F          G+ A+    +D+A  G           +           ++  + E 
Sbjct: 60  VHFVVEECGPYWAGRKALAVNLSDLAAMGGRCIASFVSIAIPRNWNAHEADELMRGVLEL 119

Query: 120 ARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH 179
           A      +  GDT         +L IN A +G               GDV++VSG LG  
Sbjct: 120 AAKWDCPVAGGDTNSWDG----RLVINVAVVGETIEATSIRRAGAQVGDVIVVSGALGGS 175

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG 239
                     L  +  L         +   L  +  + ++ D +  G+++ +     A  
Sbjct: 176 IYG-----RHLKFEPRL--------DVAAELLKLAKLNSMIDLSD-GLSSDLWHILRASH 221

Query: 240 CGIELSEAALPVKPAVRGVCELLGLD-------ALNFANEGKLVIAVERNAAEQVLAALH 292
            G  L +  +PV   VR   +++ L        AL+   + +L+  +     E +     
Sbjct: 222 AGAVLEQKRIPVHEDVRHHADVVNLSSPPALAHALHDGEDFELLFTLSPAQWETLR---Q 278

Query: 293 SHPLGKDAALIGEVVERKGVRLAGLYGVKRTL 324
           +  L      IG +V  +  R+    G  + L
Sbjct: 279 NWKLPIALTKIGTIVSEEACRIVSETGESKEL 310


>UniRef50_Q5WJP9 Thiamine-monophosphate kinase n=3 Tax=Bacillus RepID=Q5WJP9_BACSK
          Length = 330

 Score =  208 bits (529), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 61/326 (18%), Positives = 112/326 (34%), Gaps = 26/326 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEG-DRLAFSTDSYVIDPLF----FPGGN 71
             I S+         L         D A    +         D+ V    F         
Sbjct: 6   SFIRSIVPRETYQERLTHG---IGDDAAVYTGQDAWDEVVCVDAMVEGVHFRKDTLSPFQ 62

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           IG+ A+    +D+A  GA+P++      +      E L ++   M       G+ ++ GD
Sbjct: 63  IGRKALAINVSDLAAMGAVPQFYLVSIAIPPNWSAEELTSLYEGMRAVGDRYGMDLIGGD 122

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T  ++    D L ++   +G +             GDV+ V+G +G   A +  L ++  
Sbjct: 123 TVSIK----DSLVLSVTAIGRVKKGCALFRNQAQPGDVVFVTGPVGGSAAGLELLDQRGR 178

Query: 192 L------DGELVSDCAVLTPLIQ---TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGI 242
                  +   V       P ++    L + P   AL D +  G+ +   E A A G  +
Sbjct: 179 FGAFTEQERRYVHMHQEPVPQVEMGKMLAEQPYRVALNDISD-GLASESMEIAEASGVQL 237

Query: 243 ELSEAAL-PVKPAVRGVCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
            L +  +  + P +  V     +   LN   + +LV  +  +A      A  +   G+  
Sbjct: 238 VLDQQKVLELSPQMDSVLPEKRVKWSLNGGEDFQLVGTMTDSAFSSCCEA--AQQQGRHL 295

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDL 326
             IG V   +   L      ++ L +
Sbjct: 296 YKIGFVRAGEPAVLLASETGEQALQM 321


>UniRef50_B2SNW6 Thiamine-monophosphate kinase n=21 Tax=Gammaproteobacteria
           RepID=B2SNW6_XANOP
          Length = 365

 Score =  208 bits (529), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 70/320 (21%), Positives = 110/320 (34%), Gaps = 32/320 (10%)

Query: 17  QLINSLFMEAFA--NPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGN 71
            LI  L +   A  +  L   +D A L        G++LA +TD+      F       +
Sbjct: 46  DLIARLRVRIAARADVPLGIGDDAALL----HPPAGEQLAITTDTLNAGVHFPQETRADD 101

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G   +    +D+A  GA PR+ +    L        +          A A  I +V GD
Sbjct: 102 LGWKTLAVNLSDLAAMGAQPRWCTLSLSLP-HDDAAWVDLFADGFFALADAHDIVLVGGD 160

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL- 190
           T          L      +G++P +          GD + V+G  G+  A +   +    
Sbjct: 161 TTRGP------LSCAVTAIGSVPPSAALRRDGARIGDDVWVTGAPGEAAAALALWQAGQL 214

Query: 191 --------GLDGELVSDCAVLTPLIQT-LRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
                    L  +  S      P +Q  LR      A  D +  G+ A +       G G
Sbjct: 215 DVTCAAADPLHEQWRSRLLRPQPRVQAGLRLRGLAHACVDISD-GLLADLGHLCDRSGVG 273

Query: 242 IELSEAALPVKPAVRG--VCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            +L+ AALP  P   G  V +  G   L   ++ +L           V  A+        
Sbjct: 274 AQLALAALPAMPRSAGTSVAQCPGWQ-LGGGDDYELCFTAAPQHRAAVAQAMEFAE--VA 330

Query: 300 AALIGEVVERKGVRLAGLYG 319
           A  IG++V   GV +    G
Sbjct: 331 ATRIGQIVATPGVVVHDADG 350


>UniRef50_A5WHT2 Thiamine-monophosphate kinase n=4 Tax=Gammaproteobacteria
           RepID=A5WHT2_PSYWF
          Length = 372

 Score =  206 bits (526), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 60/313 (19%), Positives = 103/313 (32%), Gaps = 32/313 (10%)

Query: 17  QLINSLFMEAFANPWLAEQE------DQARLDLAQLVAEGD-RLAFSTDSYVIDPLFFPG 69
           +LI+  F  A +   L++             D A +      +     D+ V    F   
Sbjct: 5   ELISRYFTAASSEQALSQSVACTTIAKGVGDDAAVVALSSPTQWVTCVDTLVQGRHFAED 64

Query: 70  GN--------IGKLAICGTANDVAVSGAIPRYL-SCGFILEEGLPMETLKAVVTSMAETA 120
            +        IG  ++    +D+A  GA P  +     + ++      L      +    
Sbjct: 65  WDQVETLAFAIGYKSVAVNVSDIAAMGAKPHSILLALALPQQLAKEAWLSDFAKGLFHAC 124

Query: 121 RAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI-HWGAQTLTAGDVLLVSGTLGDH 179
              G+ ++ GDT   +     KL I+    G I   +          GD + VSGTLGD 
Sbjct: 125 SQFGVQLIGGDTTRSE-----KLVISVTANGFIDKALTPIYRSGAQVGDKVYVSGTLGD- 178

Query: 180 GATILNLREQLGLDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAA 236
            A          +  +L     + TP I     L     V A+ D +  G+   +     
Sbjct: 179 -ACYALYHPDTQVGKQLSHRLNMPTPRISLGNTLAAEGDVTAMIDVSD-GLVQDLSHICE 236

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHP 295
                + L    LP   A++ +     L   L   ++ +L+  +  +    +   L S  
Sbjct: 237 QSDVAVRLHLDKLPTSSALQNIELTQRLRCQLTGGDDYELLFTLPASV--SLSETLMSTA 294

Query: 296 LGKDAALIGEVVE 308
                  IGEVV 
Sbjct: 295 F-TQITCIGEVVA 306


>UniRef50_D1VW68 Thiamine-phosphate kinase n=2 Tax=Prevotella RepID=D1VW68_9BACT
          Length = 375

 Score =  206 bits (526), Expect = 7e-52,   Method: Composition-based stats.
 Identities = 55/340 (16%), Positives = 105/340 (30%), Gaps = 68/340 (20%)

Query: 38  QARLDLAQLVAEGDRLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVSGAIPRY 93
               D A +      +  +TD  +    F        ++G  A     +DV      PR 
Sbjct: 30  GVGDDCAVMHYPHSEVLTTTDMLMEGVHFDLTYIDLQHLGYKAAMVNISDVFAMNGTPRQ 89

Query: 94  LSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAI 153
           +     +++   +E ++A    +        + IV GDT   + G    + I+   +G  
Sbjct: 90  MLVSLAIDKRFSVEDIEAFYNGLRMACNKWKVDIVGGDTTSSRTG----VAISITCIGEA 145

Query: 154 PANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCA------------ 201
            +            D++ VSG LG     ++ L  +  +  + V +              
Sbjct: 146 KSEEIVYRNGAKDTDLICVSGDLGAAYMGLMLLEREKSVYYKQVDEIRTKILKAKEQKNQ 205

Query: 202 ----------------------------------VLTPLIQTLRDIP-GVKALRDATRGG 226
                                                 +I+TLR       A+ D +  G
Sbjct: 206 ALVTKLTHDLNSLGNFQPDFAGKEYLLQRQLQTEARGDIIETLRAAHIHPTAMIDISD-G 264

Query: 227 VNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD----ALNFANEGKLVIAVERN 282
           +++ +        CG  + E  LP+      + E L L+    ALN   + +L+  V   
Sbjct: 265 LSSELLHICKESNCGCRIYEKNLPIDYQTAVMAEELNLNVTTCALNGGEDYELLFTVPIG 324

Query: 283 AAEQVLAALHSHPLGKDAALIGEVVERK-GVRLAGLYGVK 321
             E++          +   LIG +     G +L      +
Sbjct: 325 DHEKIQTL-------EGIKLIGHITHANLGAQLVTRDNQE 357


>UniRef50_C6V4B8 Thiamine-monophosphate kinase n=2 Tax=Neorickettsia
           RepID=C6V4B8_NEORI
          Length = 313

 Score =  206 bits (526), Expect = 8e-52,   Method: Composition-based stats.
 Identities = 64/319 (20%), Positives = 111/319 (34%), Gaps = 37/319 (11%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNI 72
            ++++ +         L    D   LD             + D  V    FFP     N+
Sbjct: 16  HRILSEIISRIAEPFSL--LNDAFVLDD---------FVITKDLLVESIHFFPFAEPRNL 64

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFIL-EEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
            K A+    +D+A  GA P     G +L E+      L      + +     GI +  GD
Sbjct: 65  AKKALRVNLSDLAAMGAEPVGYFLGLVLGEKHKSSTWLNRFAEGLLDDQHCYGIKLFGGD 124

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T +        L I+   +G   A           GD L +SG +GD    +L+ + +L 
Sbjct: 125 TVIHSG----PLLISVTMIGK-KAEHVLSRSGAKRGDELCISGPIGDSHLGLLSYQGELQ 179

Query: 192 LDGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
            +        +  P +   RD I  V +  D +  G+ +     A      I +    +P
Sbjct: 180 ENSYFRGKYDLPEPCLDVSRDIISSVTSCIDISD-GLLSEAQHLAKNSAVSITIFFDKVP 238

Query: 251 VKPAVRGVC---ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
           +    + V      +  + L   ++ +L+  V R             P+ +   +IG V 
Sbjct: 239 ISDEAKSVLLKKPEIRKELLTAGDDYQLLFTVPREN-----------PVTRKYPVIGFVS 287

Query: 308 ERKG-VRLAGLYGVKRTLD 325
           E  G VR+   +G +   D
Sbjct: 288 EGMGEVRVLDSFGREIYFD 306


>UniRef50_Q1NMW0 Thiamine-monophosphate kinase n=2 Tax=delta proteobacterium MLMS-1
           RepID=Q1NMW0_9DELT
          Length = 337

 Score =  205 bits (522), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 60/306 (19%), Positives = 105/306 (34%), Gaps = 21/306 (6%)

Query: 28  ANPWLAEQEDQARLDLAQLVAEGDRL-AFSTDSYVIDPLFF----PGGNIGKLAICGTAN 82
           +    A        D A   A+       +TD+ +    F     P   +G+ A+    +
Sbjct: 22  SATGGARLLLGIGDDCAAWQADPTACSLATTDTLIEGVHFDSSWHPPRLLGRKAVTVNIS 81

Query: 83  DVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDK 142
           D+A  G  PR++     L         + ++  + E   A G  ++ GDT         +
Sbjct: 82  DIAAMGGTPRFVLLSLGLTGREEAAWREELLAGLVEATAAYGAHLIGGDTVHSPG----R 137

Query: 143 LFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVS---- 198
           + +    +G +             GD L VSG LG   A +   R  LG +         
Sbjct: 138 VMLTVTVLGEVAEAELCRRDGGRQGDSLWVSGPLGWAAAGLELCRRGLGTEERWQPLVKA 197

Query: 199 --DCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVR 256
             +      L + L     V A++D +  G+   +   AAA G G E+    LP    ++
Sbjct: 198 HLNPDAQVALGRALARGRLVHAMQDLSD-GLATDLAHLAAASGQGAEVKAELLPQAELLQ 256

Query: 257 GVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGV 312
                   D   +      + +L+ +      +  +AAL           IG++V   GV
Sbjct: 257 AAATHCEADPTTWTIAGGEDYQLLFSAPPEH-DPAIAALSQRDKLPALHRIGQLVAGAGV 315

Query: 313 RLAGLY 318
            L+   
Sbjct: 316 FLSRGE 321


>UniRef50_D1CF57 Thiamine-monophosphate kinase n=1 Tax=Thermobaculum terrenum ATCC
           BAA-798 RepID=D1CF57_THET1
          Length = 334

 Score =  204 bits (521), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 65/310 (20%), Positives = 119/310 (38%), Gaps = 26/310 (8%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLV-AEGDRLAFSTDSYVIDPLFF----PGGNI 72
           LI  L  +     +  +       D+A L  +    L  + DS V    F         +
Sbjct: 11  LIKRLVDKL--PEYGRDVIVGPGDDVAVLRTSSDKYLLATIDSQVEGIHFLFEYTGARQL 68

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+ AI    +D+A  G  PR+      L +   ++ ++ +   +   + A G+ ++ G+ 
Sbjct: 69  GEKAIAINVSDIASMGGQPRHALVSLALPDSCQLKLVEELYEGIYSASHAYGLDVIGGNI 128

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL-- 190
              + G    L ++   +G +             GD + V+G LG   A    L  +L  
Sbjct: 129 SSSRSG----LLVDVCLLGEVEPEHLVLRSGAAPGDGIYVTGWLGSSAAGFELLCSKLRN 184

Query: 191 ---GLDGELVSDCAVLTPLI---QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEL 244
               +  EL S        +   ++L     V A+ D +  G+ + +     A G G  +
Sbjct: 185 CDERIWEELTSSHLTPKARLYEARSLVATGAVSAMIDISD-GLISDLGHILEASGVGAVV 243

Query: 245 SEAALPVKPAVRGVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
               LP+  AVR V   LG DAL +      + +L++  +R   + +  A  +   G   
Sbjct: 244 YTDRLPIATAVREVASTLGKDALRWALSGGEDYELLLTGDRRVLDGI--ASDNGLGGTPL 301

Query: 301 ALIGEVVERK 310
            LIGE++ + 
Sbjct: 302 TLIGEILPQS 311


>UniRef50_B2V6K1 Thiamine-monophosphate kinase n=3 Tax=Aquificales
           RepID=B2V6K1_SULSY
          Length = 314

 Score =  204 bits (520), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 56/336 (16%), Positives = 102/336 (30%), Gaps = 47/336 (13%)

Query: 1   MNNIQLAHGSGGQAMQQLINSL--FMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTD 58
           M  I    G  G     LI  L   +       L         D A +   G  + F+ D
Sbjct: 1   MERIN-QIGEFG-----LIERLNQILPIHDKDVL----VGYGDDCACVNINGKLILFTVD 50

Query: 59  SYVIDPLFFP----GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVT 114
             V +  F        ++G        +DV   G +PR+      L + L    ++ V  
Sbjct: 51  IQVENSHFLKGKIKPEDLGWKLATSNVSDVVACGGLPRWALLSLALPKDLEYSFIEKVYL 110

Query: 115 SMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSG 174
            + E     G   + G+         +++ I+    G                  + +SG
Sbjct: 111 GIKEAQDYYGFYTIGGNCSSS-----NQIMIDMTMAGETEK--FISRSAAKPNQKIYLSG 163

Query: 175 TLGDHGAT----ILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAV 230
            LG   A     +++ +E    +  L++        I  +  I    A  D +  G+ + 
Sbjct: 164 NLGCSKAGLELILMDKQEYEDFEIALINKHYRPKARIDLIEKIKQASACIDISD-GLTSD 222

Query: 231 VHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQ 286
           +   +      I + +  L +   ++  C   G D     L    E ++ +  E++    
Sbjct: 223 LSHISKKSNVKIIIEKEKLKIDENLKKFCLKYGKDPLDYILTSGEEYEVALISEKD---- 278

Query: 287 VLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKR 322
                       D   IG   E  GV L     +  
Sbjct: 279 -----------LDLIEIGYTEEGFGVFLKEGDKIVE 303


>UniRef50_Q54757 Thiamine-monophosphate kinase n=9 Tax=Cyanobacteria
           RepID=THIL_SYNE7
          Length = 327

 Score =  204 bits (520), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 58/309 (18%), Positives = 107/309 (34%), Gaps = 35/309 (11%)

Query: 30  PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLAICGTANDVA 85
           P     +D A L        G +L  S+D  V    F     P   IG  A     +D+A
Sbjct: 23  PAEQRGDDAAIL----TPPAGQQLVVSSDVLVEGIHFSEATTPPAAIGWRAAAANLSDLA 78

Query: 86  VSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFI 145
             GA P  ++    L     +  L+ +   +    +     ++ GD             +
Sbjct: 79  AMGATPAGITLALALPSDRRLSWLQQIYQGLDRCLKQYDCPLIGGDLSRSPTA-----TL 133

Query: 146 NTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGEL----VSDCA 201
               +G +  N      T   GD ++ +GT G     + +L  +  L   L    ++   
Sbjct: 134 AVTALGWVNPNRVIRRSTAQVGDWIMATGTHGLSRLGLGHLLGEWTLAEPLRDQAIAAHQ 193

Query: 202 VLTPLIQTLRDIP---------GVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVK 252
              P +  +  +           V  +   +  G+   V +   A   G  +   ALP+ 
Sbjct: 194 APKPRLDVVPLLARSQPAGTVWRVAGM--DSSDGLADAVLQICRASQVGAVI--EALPLP 249

Query: 253 PAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGV 312
                  + L   AL    + +LV+ +  + A+ +L  L     G+ A +IG++ E+  V
Sbjct: 250 ATTSFDRDRLIQAALYGGEDFELVLCLSPDWAQALLELL-----GEQAQVIGQITEKPVV 304

Query: 313 RLAGLYGVK 321
           +L      +
Sbjct: 305 QLRLSDRTE 313


>UniRef50_Q10XH5 Thiamine-monophosphate kinase n=6 Tax=Cyanobacteria
           RepID=Q10XH5_TRIEI
          Length = 341

 Score =  204 bits (519), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 53/335 (15%), Positives = 105/335 (31%), Gaps = 50/335 (14%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP----GGN 71
           Q+L+  L       P     +D A L           L  +TD+ V    F        +
Sbjct: 10  QELLKKL---RHFCPENIIGDDAAIL----PTQPNKSLVVTTDTLVDGVHFSDRTTSPED 62

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  +     +D+A  GA P  ++    L    P+   + +   ++E  +     IV GD
Sbjct: 63  VGWRSAAANLSDIAAMGAFPIGITIALGLTVDTPIAWCEQLYQGISECLQPYNTPIVGGD 122

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
                        I+    G I              +V++ +G  G   A +  L     
Sbjct: 123 IVRSPVS-----TISITAFGQIDGGYTILRSNCQPKNVIVATGVHGASRAGLELLLYPEL 177

Query: 192 LD-------GELVSDCAVLTPLIQTL------------------RDIPGVKALRDATRGG 226
            +        +L+       P +  L                  ++   V  +   +  G
Sbjct: 178 GESLTELERSDLILAHQRPKPRLDILDTLWDCLSLNSFSATKGSKNSILVGGM--DSSDG 235

Query: 227 VNAVVHEFAAACGCGIELSEAALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAA 284
           +   + +   A   G  +    +P+  ++      E     AL    + +LV+ +  N  
Sbjct: 236 LADAIIQICQASQIGARIERNQIPIPHSLTKFVSDEQALNWALYGGEDFELVLCLPPNCG 295

Query: 285 EQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYG 319
           ++++  +     G  AA++G       + L    G
Sbjct: 296 QELVKRI-----GVGAAIVGTTTNNTDILLIDSQG 325


>UniRef50_UPI00016C3B48 thiamine-monophosphate kinase n=1 Tax=Gemmata obscuriglobus UQM
           2246 RepID=UPI00016C3B48
          Length = 303

 Score =  203 bits (518), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 60/314 (19%), Positives = 103/314 (32%), Gaps = 37/314 (11%)

Query: 21  SLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIGKLA 76
                A +   L   +     D A L      L  +TD  +    F         +G+ A
Sbjct: 12  RARTPAHSRVRLGPGD-----DCAALEPPARELLVTTDMLMDGTDFILSEVGARRVGRKA 66

Query: 77  ICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQ 136
           +    +D+A    +P   +    L      +  + +   + + A A  + IV GDT    
Sbjct: 67  MAANLSDIAAMAGVPTAATVSLALPNSHGADLARELFLGLRDVADAFNVPIVGGDTNS-- 124

Query: 137 RGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGEL 196
                 L ++   +G               GD + VSG LG                   
Sbjct: 125 --WAGSLVVSVTALGEATVRGPVRRGGARPGDWIFVSGPLGGSILGHHL----------- 171

Query: 197 VSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVR 256
             D          L ++  ++A+ D +  G++A ++       CG  L   A+P+  A R
Sbjct: 172 --DFTPRVAEALQLHELVELRAMCDISD-GLSADLNHICEESRCGAVLDGDAVPITDAAR 228

Query: 257 GVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGV 312
            +    G   L        + +LV  V      ++L    +       A IGE VE  G+
Sbjct: 229 ELSRTSGRTPLQHALGDGEDFELVFTVSPEDGTKLL----ARRPFPSLAKIGECVET-GL 283

Query: 313 RLAGLYGVKRTLDL 326
            L  + G ++ L  
Sbjct: 284 WLE-INGTRQPLAP 296


>UniRef50_B1CC54 Putative uncharacterized protein n=1 Tax=Anaerofustis
           stercorihominis DSM 17244 RepID=B1CC54_9FIRM
          Length = 324

 Score =  203 bits (517), Expect = 8e-51,   Method: Composition-based stats.
 Identities = 61/334 (18%), Positives = 121/334 (36%), Gaps = 25/334 (7%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARL-DLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+   + +  +            +       D A L  + D    STD     P+     
Sbjct: 4   GKLSNETLEKILFNKIKIKNKEVKIGAGIGKDTAMLDFQNDLFIISTD-----PITGSKN 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            IGKL +  + ND+A + A P  +    ++     ++ ++ ++  +  T     + ++ G
Sbjct: 59  GIGKLCVNISCNDIATAMARPVAIMITMLIPTYAKIKDVEEIIDDILLTCDENNVDLIGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T+V     V+K  ++   +G       +      AGD +++S   G  G+ I  L  + 
Sbjct: 119 HTEVTSS--VNKFILSGVCIGRKEKRKEFLPS---AGDKVVMSKYAGLEGSAIAALDLEE 173

Query: 191 GLDGELVSDCAVLTPLI---------QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            +   L  +    T  +           +     V  L DAT GG+   V E A     G
Sbjct: 174 EVKNILTKEEFEKTRELINHTNVIKEGLIARNHEVSLLHDATEGGIFGGVWEMATNSNLG 233

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             ++   + +    + + E  G+D     + G ++   + +   +++  L        A+
Sbjct: 234 AVINTDDILILDETKKIAEHFGIDPYKLISSGVMLFITKNDK--ELIEDLKKE--NIPAS 289

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
            IG + E K +        K  L  P  + L +I
Sbjct: 290 TIGYLTEEKEIYTI-KNNKKEILSPPEQDELYKI 322


>UniRef50_C0GR51 Thiamine-monophosphate kinase n=1 Tax=Desulfonatronospira
           thiodismutans ASO3-1 RepID=C0GR51_9DELT
          Length = 315

 Score =  203 bits (516), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 78/326 (23%), Positives = 118/326 (36%), Gaps = 35/326 (10%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNI 72
           +++NSLF     +  +   +D A L           L  S+D ++ D  F    F   +I
Sbjct: 10  EIVNSLFPREHPHMVVGRGDDCAVLKCPA------SLCMSSDLFLEDVHFRTRYFTPEDI 63

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA P   +   I    L  E  +++++SMAE      +A+  GD 
Sbjct: 64  GHKALAVNLSDLAAGGARPLGFNLNLIWPVYLDEEFCRSMLSSMAELGAKFKLALTGGDL 123

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE---Q 189
                     L +     G  PA           GDVL V G  G     +  L E    
Sbjct: 124 SF-----GKSLGLAVCIWGKSPARQML-RGKAEPGDVLFVVGKAGLAACGLSLLEENDPG 177

Query: 190 LGLDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSE 246
           L    E V+      PL++    L  I  VK L D +  G+   +  F    G G+E+  
Sbjct: 178 LDRYPECVAQHLRPRPLVREGQVLAGIEEVKGLMDVSD-GLARDLPRFCRR-GTGVEICS 235

Query: 247 AALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAAL 302
               V P V   C   GLD     L    +  L+ A  R   + V   +       D   
Sbjct: 236 D-FRVHPEVAFFCRDRGLDPLATALKGGEDYALLGACTRKGWDTVKKKI------LDCRR 288

Query: 303 IGEVVERKGVRLAGLYGVKRTLDLPH 328
           +G V ++ G+ L       +  D   
Sbjct: 289 LGTVTDKPGIFLQDRELGLKGFDHFE 314


>UniRef50_Q1QUD0 Thiamine-monophosphate kinase n=1 Tax=Chromohalobacter salexigens
           DSM 3043 RepID=Q1QUD0_CHRSD
          Length = 319

 Score =  202 bits (515), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 69/304 (22%), Positives = 108/304 (35%), Gaps = 16/304 (5%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLF---FPGGNI 72
            +I   F    + P +         D A L  E G  LA S D+ V+D  F    P   I
Sbjct: 6   DIIARYFTTPDSEPPMPGVALGVGDDCALLSPEAGHELALSVDTSVVDVHFPGDAPPEAI 65

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G  A+    +D+A  GA PR       L      + L+       E  R     ++ GD 
Sbjct: 66  GHRALAVALSDLAAMGARPRGCLMALTL-SHAEPDWLERFAHGFRELGRRTATPLIGGDV 124

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR-EQLG 191
                     L I    +G +PA           G+ L V+G+LG   A +   +     
Sbjct: 125 TRGS------LSIGVTVIGDVPAGQALRRTGAAPGERLAVTGSLGGGHAGLRMWQAGGHD 178

Query: 192 LDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           L   L++     TP +   + +  + +       G+ A +     A G G  LS   LP+
Sbjct: 179 LADPLLAAYLTPTPQLAAGQALRDLASAGLDISDGLLADLGHLCRASGVGAVLSPDDLPL 238

Query: 252 KPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
            P++      E     ALN  ++ +L+++V   A         +         IG V   
Sbjct: 239 APSLDMTLGREAALHAALNGGDDYQLLVSVPDAAWADAQQRCAACD--VALTEIGRVTAE 296

Query: 310 KGVR 313
            G+R
Sbjct: 297 PGIR 300


>UniRef50_B3DWZ3 Thiamine monophosphate kinase n=1 Tax=Methylacidiphilum infernorum
           V4 RepID=B3DWZ3_METI4
          Length = 319

 Score =  202 bits (515), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 62/317 (19%), Positives = 108/317 (34%), Gaps = 35/317 (11%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRL--AFSTDSYVIDPLF---FPGG 70
           +QL+  L  +   N            D A +   G+ L   F  D+ V +  F    P  
Sbjct: 33  EQLLEILLKDFQTN---RPGIVGIGEDCAVVQGRGNDLYYLFKVDATVENVHFEAGTPPE 89

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            IG+ A+    +D+A  G  P Y   G  + +   +E +K +   +   A+A  + I+ G
Sbjct: 90  LIGRKALARALSDIAAMGGEPLYALVGIGISKDQKIEKIKKIYEGIRSLAQAFDLLIIGG 149

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           +T V +     +LF+  +  G             T GD L V+G LG             
Sbjct: 150 ETTVSE-----QLFLVVSLWGKTEGYKPVLRSGATDGDGLFVTGVLGGS----------- 193

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
                            + L +    KA+ D +  G+   +   A A   G E+   A+P
Sbjct: 194 -FQSGHHLVFMPRIKEGKWLANGRWAKAMMDISD-GLAKDLPRMAKASSIGFEIDFDAIP 251

Query: 251 VKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERK 310
           ++             AL    + +L+ +V +    +++    S P       IG   +R 
Sbjct: 252 IRGGYTIKA------ALTEGEDYELLFSVAKEKENKLI---QSWPFDVPLKKIGFFSQRG 302

Query: 311 GVRLAGLYGVKRTLDLP 327
                  +        P
Sbjct: 303 KRNFPDEFRGFDHFQEP 319


>UniRef50_B4D453 Thiamine-monophosphate kinase n=1 Tax=Chthoniobacter flavus
           Ellin428 RepID=B4D453_9BACT
          Length = 306

 Score =  201 bits (513), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 65/300 (21%), Positives = 106/300 (35%), Gaps = 30/300 (10%)

Query: 20  NSLFMEAFAN-PWLAEQEDQARLDLAQL--VAEGDRLAFSTDSYVIDPLFFPGGN---IG 73
           + L      + P  AE    A  D A +    +       TD  +    F P  +   +G
Sbjct: 18  DRLVAALTRDLPHGAEVLVGAGDDCAVIGRKRDARWQLLKTDVVIEGIHFLPDEDARRVG 77

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
             A+C   +D+A  G IP +           P++ +KA+   + + AR   + IV G+T 
Sbjct: 78  WKALCRAISDIAAMGGIPAHALITLAAPAATPVDRVKALYAGLRKAARKYDVGIVGGETS 137

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
                    LF+N A  G +             GD L V+G LG   A            
Sbjct: 138 RSPG----PLFLNIALTGWVERQQCVLRSGGRPGDSLYVTGRLGGSLAGKHL-------- 185

Query: 194 GELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
                D        + L      +A+ D +  G+ A +   AAA  CG  + EA LP+  
Sbjct: 186 -----DFQPRIEEARWLVSHFKPRAMMDLSD-GLAADLPRLAAASQCGYTIDEACLPLNT 239

Query: 254 AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
                       A++   + +L+ A+   +A  + AA            IG ++    +R
Sbjct: 240 GCTPT------QAMSDGEDFELLFALPARSATALEAAWKKRFPRLPLTQIGRLIPHSAIR 293


>UniRef50_Q7NG75 Thiamine-monophosphate kinase n=1 Tax=Gloeobacter violaceus
           RepID=Q7NG75_GLOVI
          Length = 328

 Score =  201 bits (513), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 72/334 (21%), Positives = 118/334 (35%), Gaps = 30/334 (8%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP----GGN 71
           + LI  L       P +         D A +      L  +TD    D  F        +
Sbjct: 9   RGLIARLGRFFGQAPHILVP---GGDDAAVVAPGSGALVATTDLLFEDVHFGDRTTGPFD 65

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           +G  +     +D+A  GA P  +  G  L  G  +E ++A        +   G  ++ GD
Sbjct: 66  VGWRSAAANLSDLAAMGAAPFGMLVGLGLSPGTSVEWVEAFYEGFTACSAPVGALLLGGD 125

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE--- 188
           T   +        +    +G +             GD L+V+G LG   A +  L E   
Sbjct: 126 TCRAKSR-----TVAVTALGTVDPRRILRRNAARPGDALVVTGHLGASRAGLAVLLEAER 180

Query: 189 ----QLGLDGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
                  +   +V+      P ++    +  + G  A  D T  G+   + +  A  GCG
Sbjct: 181 YAHLGSPVREAVVAAHRRPKPRLEVPPLVFALSGRAAAMD-TSDGLTDAIAQVCAQSGCG 239

Query: 242 IELSEAALPVKPAVRGVCELLGLDA-LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
             +  A LP+  A   V     +   L    + +L+IA+E  AA Q++  L +  +G   
Sbjct: 240 AVVDLAVLPIDAATAQVAGKQAIAWALGGGEDYELLIALEPGAAVQLVERLAA--IGIGG 297

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
           A++G  V    V         R L  P  E   R
Sbjct: 298 AIVGRAVAGDRVV----DTEDRPLAAPGFEHFNR 327


>UniRef50_D2RH67 Thiamine-monophosphate kinase n=1 Tax=Archaeoglobus profundus DSM
           5631 RepID=D2RH67_ARCPR
          Length = 298

 Score =  201 bits (513), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 64/288 (22%), Positives = 110/288 (38%), Gaps = 31/288 (10%)

Query: 44  AQLVAEGDRLAFSTDSYVIDPLF---FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFIL 100
             LV  G RLA +TD       F        IG LA+    +D+A  GA P +      L
Sbjct: 29  CALVDVGTRLALTTDCLHEKTDFPKGIKPEEIGHLALAINLSDLASCGAKPLFFLYTITL 88

Query: 101 EEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWG 160
            +   +E  + ++  M   A   G+A+V GDT        D+L I+   +G        G
Sbjct: 89  SDYW-IEYFERILKGMKNLADKYGVAVVGGDTDF-----GDELHISGFAIGKAE--RFVG 140

Query: 161 AQTLTAGDVLLVSGTLGDHGATILNLREQLG-LDGELVSDCAVLTPLIQT-LRDIPGVKA 218
                 GD + V+G LG    ++  L       +           P ++  LR      +
Sbjct: 141 RDGAKVGDKICVTGLLGKAQLSLEQLMNGFSRYEIAYPDSLFKPEPRVEEGLRIAKHANS 200

Query: 219 LRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA-LNFANEGKLVI 277
           + D +   +   +H+ A   G GI++ E  +P+    + V     L+  L    + +LV 
Sbjct: 201 MTDISDS-LAISLHQIAKRSGVGIKIYEEKIPLDHLTKFVDYEKALELFLYSGGDYELVF 259

Query: 278 AVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLD 325
             +++                +   IGEV+E +GV +    G  + ++
Sbjct: 260 TSKKS----------------EYIEIGEVIEDEGVWIVRRDGRVKEVE 291


>UniRef50_Q0VMI1 Thiamine-phosphate kinase n=1 Tax=Alcanivorax borkumensis SK2
           RepID=Q0VMI1_ALCBS
          Length = 325

 Score =  201 bits (511), Expect = 3e-50,   Method: Composition-based stats.
 Identities = 64/315 (20%), Positives = 104/315 (33%), Gaps = 30/315 (9%)

Query: 17  QLINSLFM-EAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNI 72
            LI   F      +  L   +D A L        G +L  + D+ + D  F       ++
Sbjct: 26  SLIRRYFHHRQGDSVVLGPGDDAAIL----APPVGQQLVMTQDTSLADRHFPSDMAPEDV 81

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G   +    +D+A  GA+P +      L   +  + L      + E A  AGI++V GD 
Sbjct: 82  GYRCLAVNISDLAAMGAMPLWFLLSLTLPR-VDEDWLAGFSNGLFELADQAGISLVGGDI 140

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                     L I+    GA+P       +   AGD + V G  G     +   +     
Sbjct: 141 TRGP------LAISIQATGAVPPGQALRREGACAGDRICVGGVTGGGLLGLEQWQAGQRY 194

Query: 193 DGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACG-CGIELSEAALPV 251
              +             +       A  D +  GV A ++    A G  G  + EA+LP 
Sbjct: 195 GPAIEHFRRPRPQWELGMALRGQASACIDISD-GVLADLNHILQASGALGACIDEASLPE 253

Query: 252 KPAVRGVCELLGLDA--LNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
            P V   C      A  L   ++              +       P+ +    +G +  +
Sbjct: 254 DPCVLAGCSADKQRALQLQGGDDY-----------LLLFTLPPPLPIPEGCYCLGRIEAQ 302

Query: 310 KGVRLAGLYGVKRTL 324
            G+RL    G  R L
Sbjct: 303 PGIRLRQHDGTVRAL 317


>UniRef50_C6A3P3 Hydrogenase expression/formation protein HypE n=2 Tax=Thermococcus
           RepID=C6A3P3_THESM
          Length = 349

 Score =  201 bits (511), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 70/329 (21%), Positives = 128/329 (38%), Gaps = 21/329 (6%)

Query: 12  GQAMQQLINSLFMEAFA-NPWLAEQEDQARLDLAQLVAEGD-RLAFSTDSYVIDPLFFPG 69
           G+   +++N++ ++  + N        +   D A L  +    L  +TD  +  P     
Sbjct: 26  GKIRSEVLNNIILKNISVNDPKIVFGPKEGFDAAVLEYDEKNYLVIATDPILGVP----K 81

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
            + G       ++DVAV GAIP++L    +L  G   E L +V+  + E  +  G +I+ 
Sbjct: 82  EHFGFFTYHFASSDVAVFGAIPKWLIVNLLLPNGTTEEDLNSVMRELNEECKKYGTSIIG 141

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDH----GATILN 185
           G T V               +G +  +          GD ++++  +        A    
Sbjct: 142 GHTGVYSTTRSFTATTTA--IGLVKKDELKLPL-AKPGDDIIITKGIAIEFAVGAAWFRT 198

Query: 186 LREQLGLDGELVSDCAVLTPLI----QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
              +  L    +S    +  L       L      + + D T GG+   +HE A     G
Sbjct: 199 EELKKILSPSQISSLREMYTLETVVKDALLAKKFARGMHDVTEGGL-TTLHEIADNSEVG 257

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
            E+    L + P V+ V +  G++ L  ++ G L+I   +    +++ ALHSH  G +A+
Sbjct: 258 FEVYYEKLHMPPLVKKVVKFYGVNPLTVSSTGTLIIISPQENTSKLIKALHSH--GINAS 315

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAE 330
            +G+  E K   L    G K        +
Sbjct: 316 TVGKFTEEKERALI-KKGRKEEFPKFEKD 343


>UniRef50_A4WH94 AIR synthase related protein domain protein n=5
           Tax=Thermoproteaceae RepID=A4WH94_PYRAR
          Length = 335

 Score =  200 bits (510), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 81/331 (24%), Positives = 122/331 (36%), Gaps = 23/331 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQ-EDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+    L+  L +                  D A +   G  L   TD     P+     
Sbjct: 4   GKVHPSLLEKLVLTRRGAARGDVVVGPAIGEDAAVVDLGGKYLVAHTD-----PITGSVN 58

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            +G LA+    NDVAV G  P +LS   +L  G   + L A+   M   AR  G+ IV G
Sbjct: 59  LLGSLAVYVPTNDVAVRGVEPMWLSVALLLPPGASDDLLDAITRQMDMAARRLGVTIVGG 118

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN----- 185
            T+V    AV +       MG    +          GDV++++ + G   A+IL      
Sbjct: 119 HTEVTT--AVTRPVAVVTAMGV--GSRFVSTSGAKPGDVVVMTKSAGQETASILASDFAE 174

Query: 186 LREQLGLDGELVSDCAVLTPLI----QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
              + G+  E +     L   I    + L       ++ D T GGV   + E A A    
Sbjct: 175 EALRRGVPAEALERARGLIAEISVAREALALADLATSMHDPTEGGVANGLAEIAYASKVS 234

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
           I++    + V   V  +C    +D L   + G L+  V R    + L  L    LG   A
Sbjct: 235 IDVRRKDVVVYREVEALCRAFRIDPLETLSSGVLLATVPRGRLGEALERLQK--LGVPHA 292

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPL 332
           +IGEV    G  +      +R  +    + L
Sbjct: 293 VIGEVKPPSGYLVKIDD--RRYNEPYVEDKL 321


>UniRef50_A3VRR7 Thiamine-monophosphate kinase n=1 Tax=Parvularcula bermudensis
           HTCC2503 RepID=A3VRR7_9PROT
          Length = 320

 Score =  199 bits (508), Expect = 8e-50,   Method: Composition-based stats.
 Identities = 65/316 (20%), Positives = 117/316 (37%), Gaps = 21/316 (6%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNIG 73
            LI+           +  Q+D A           + +  + D  V    F      G   
Sbjct: 5   SLIDRYLAPLAIEGAVGLQDDAALF---------EGMIITKDLLVDGVHFRSCDGWGAAA 55

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
           + A+    +D+   GA P   + G +  + +  E + A +  ++      G+ ++ GDT 
Sbjct: 56  QKALRVNISDLVACGARPAAFALGVVWPKAVTEEEIAAFMEGLSADCARYGLGLIGGDTT 115

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
             +  +   L I+   +G               GDV++V+GT+G+    + +L  ++   
Sbjct: 116 RHRADSG-PLTISVTMVGPPAPEGPLRRSGAQVGDVVMVTGTIGEAVLGLKSLLGEIAPT 174

Query: 194 GELVSDCAVLTPLIQTL-RDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVK 252
            E V       P I  +        A  D +  G+ A     A A G  + L  AA+P+ 
Sbjct: 175 SEGVEAYLRPRPPIDLVDALARYAHAAIDISD-GLLADATHIAEASGVVLGLDAAAIPLS 233

Query: 253 PAVRGVCELLG---LDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
           P+ R   E  G   L  L   ++ +++  V ++  + + AA  +         IGEV E 
Sbjct: 234 PSARAYAEDSGDALLSLLGGGDDYQVIATVPQDNVDPLRAA--AATAQVPLTSIGEVREG 291

Query: 310 -KGVRLAGLYGVKRTL 324
             G  L G  G +   
Sbjct: 292 AAGTVLRGGDGKEIAF 307


>UniRef50_D1A2J3 AIR synthase related protein n=1 Tax=Thermomonospora curvata DSM
           43183 RepID=D1A2J3_THECD
          Length = 352

 Score =  199 bits (507), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 72/318 (22%), Positives = 112/318 (35%), Gaps = 32/318 (10%)

Query: 31  WLAEQEDQARLDLAQLVAEG-DRLAFSTDSYVIDPLFF-------PGGNIGKLAICGTAN 82
            L    D A+ D A    +G   L   +D YV  P F           +IG        +
Sbjct: 36  RLLAGAD-AQDDCAVFRLDGVQELVVGSD-YVRGPKFGLYELGYLDDYDIGYYLAMANFS 93

Query: 83  DVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDK 142
           D+A  GA P  L       + +P E    V+  + +     G   V GD      G  ++
Sbjct: 94  DIAAMGAQPIALLSVVRYPKTMPDERFAQVLQGINDACARVGAPNVGGDI-----GTAER 148

Query: 143 LFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELV----- 197
           L ++ + +G + A           GD L ++G  G   A      +    D  L      
Sbjct: 149 LILSASAVGVVEAGRSLLRGGARPGDRLCITGPTGVAAAAQKYFGKLDVADTRLSPQAEE 208

Query: 198 ------SDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
                      L P  ++L     V + +D +  G+ A +   AA  G G  + E ALPV
Sbjct: 209 LLLNAWKRPQALVPEGRSLSTSGLVTSCQD-SSDGLKAGIESIAARSGVGFTVEEDALPV 267

Query: 252 KPAVRGVCELLGLD--ALNFAN--EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
             AV  V +L   +   L   +  + +L+  V     E++     +H        IG   
Sbjct: 268 VGAVEEVAKLSDTELTPLLLGDSVDFQLIFTVPEEHVEELQEIFAAHGHSA-FHDIGFAT 326

Query: 308 ERKGVRLAGLYGVKRTLD 325
           E   + L G  G+ R L 
Sbjct: 327 EEPDLLLRGSDGITRRLP 344


>UniRef50_C6QHP2 Thiamine-monophosphate kinase n=1 Tax=Hyphomicrobium denitrificans
           ATCC 51888 RepID=C6QHP2_9RHIZ
          Length = 341

 Score =  199 bits (507), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 68/334 (20%), Positives = 110/334 (32%), Gaps = 28/334 (8%)

Query: 17  QLINSLFMEAFANPW--LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGGN 71
           +LI +                +D A L  A     G  L FS+D  +    FF      +
Sbjct: 20  ELIQTYLAPLAEGMAGAFGLTDDAAFLRPA----SGSDLVFSSDPIIAGVHFFHDDRPAD 75

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
           I   A+   A+D+A  GA P        L E    + + A    +       G  ++ GD
Sbjct: 76  IAWKALACNASDMAAKGAAPVAYLLTLALPEAPERDWIAAFADGLRAAQSEFGCKLIGGD 135

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T V        L I    +G++ A          AGD + VSGT+GD    +   R+   
Sbjct: 136 TDVTPG----PLSIGITIIGSVAAGAFIPRGGAKAGDHVFVSGTIGDAALGLALRRDPSQ 191

Query: 192 LD-------GELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
                      L+       P +          ++  D +  G+   +   A A   GI 
Sbjct: 192 FSTLTDDQRALLLDRYLRPKPRLALAGPVRSHARSALDVSD-GLIKDLRRLAGAS-LGIA 249

Query: 244 LSEAALPVKPAVRGVCELL---GLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA 300
           +    +P+ P  R             L   ++ +L+IAV     E+ +    +   G   
Sbjct: 250 VKFDDIPLSPPARAALAANPNVRDSILAGGDDYELLIAVAPENIEKFVT--SAGESGIRV 307

Query: 301 ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR 334
             IG +  +    +    GV   L  P  +   R
Sbjct: 308 HDIGVLESKITTVVLDPSGVPIALRRPGYDHFSR 341


>UniRef50_Q8TVM0 Selenide, water dikinase n=1 Tax=Methanopyrus kandleri
           RepID=SELD_METKA
          Length = 334

 Score =  199 bits (507), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 72/333 (21%), Positives = 106/333 (31%), Gaps = 33/333 (9%)

Query: 8   HGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF 67
           HG   +  Q  +  L             E     D A +  +G  +  S D +   P+  
Sbjct: 14  HGUACKLPQGDLEDLLKGVELPEEGGRVEVGVGDDAAVIRVDGGYVIQSVDFFT--PIHP 71

Query: 68  PGGNIGKLAICGTANDVAVSGA-IPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
                G++A   + NDV   GA     +         LP E  + ++   A+  R     
Sbjct: 72  DPYTQGRIAANNSINDVFAMGATEVLSVLVVSGFPRELPEEDAREMLQGFADQCREVDAL 131

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN- 185
           IV G T +          +     G      +        GDVL ++  LG   A     
Sbjct: 132 IVGGHTIMNPW-----PILGGCVTGFAE--RYVTVGGAEPGDVLYLTKPLGTQPAMAALR 184

Query: 186 ----LREQLGLDGELVSDCA--------VLTPLIQTLRDIPGVKALRDATRGGVNAVVHE 233
               +R+Q   D EL              L    +   ++ GV A+ D T  G+     E
Sbjct: 185 LPEDVRKQFLTDSELEEAVDLAVEVMTEPLKDAAEAALEV-GVHAMTDVTGFGLKGHAGE 243

Query: 234 FAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANE----GKLVIAVERNAAEQVLA 289
            A A G  + +    LPV P    +   LG   L         G L++AV    AE +  
Sbjct: 244 MAEASGVRVVI--ERLPVIPGTTELSRALGYG-LERGESAETAGGLLVAVPEEHAEDLED 300

Query: 290 ALHSHPLGKDAALIGEVVERKGVRLAGLYGVKR 322
           A            IG V E  GV + G      
Sbjct: 301 AFERRD--VWYRRIGRVEEGSGVEVRGDVEEVE 331


>UniRef50_A1K2S2 Thiamine-phosphate kinase n=9 Tax=cellular organisms
           RepID=A1K2S2_AZOSB
          Length = 336

 Score =  199 bits (506), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 66/324 (20%), Positives = 104/324 (32%), Gaps = 22/324 (6%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGK 74
           LI   F     +  LA  +D A L        G  LA S D  V    FFP     ++G 
Sbjct: 25  LIQRHFSRPCGHTALAGGDDAALL----HPRPGMELAVSADMLVAGTHFFPDADPHDLGW 80

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
             +    +D+A  GA PR+     +         + A        A   G+ +  GDT  
Sbjct: 81  KTLAVNVSDLAAMGADPRWALLS-LALPAADDAWIAAFADGFYACAERFGVDLAGGDTTR 139

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG 194
                   L ++   +G +P           AGD + VSG  G     +  LR       
Sbjct: 140 GP------LTLSVTILGEVPRGQALTRAGANAGDDIWVSGQPGLAALGLEMLRGTFAPTA 193

Query: 195 E---LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           +    ++      P +   + + G+ +       G+   +        CG  L E ALP+
Sbjct: 194 DGERCLAALHRPQPRVALGQALRGLASAALDISDGLLGDLGHILVQSRCGATLHEDALPL 253

Query: 252 KP--AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
               A      L     L   ++ +L+      A   + A   +  L      IG + + 
Sbjct: 254 AALYATGASPALARRCLLAGGDDYELLFCAPPAARAAITALGPA--LALPLTRIGTLSDA 311

Query: 310 KG-VRLAGLYGVKRTLDLPHAEPL 332
            G V L    G    L     +  
Sbjct: 312 PGTVALRSADGTLTALAARGYDHF 335


>UniRef50_A3DPV0 AIR synthase related protein domain protein n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DPV0_STAMF
          Length = 339

 Score =  198 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 54/320 (16%), Positives = 115/320 (35%), Gaps = 25/320 (7%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG---NI 72
           +++I+    +     +L   +D        ++    R+  + D Y I  +  P     ++
Sbjct: 18  EKIISKYIHKPLPGEYLDYPDDA-----RDILPISPRILVNIDGYSISSMKLPWRTWSDV 72

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G +A+ G  +D    GA+PR +     L   +    ++ +   + E +R   + ++ GDT
Sbjct: 73  GYVAVAGAISDQIAKGAVPRDIMVSLGLPPSMEASIVEEIYKGIDEASRDYNLRLLGGDT 132

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
                      +I+ A +G   A      +    GD+++V+   G  G   +N  E    
Sbjct: 133 NSSS-----TPWISVAVIGYTTAKKPPSRKNAKPGDIVVVTSLYGAMGYVAINGVENAIH 187

Query: 193 DGELVSDCAVLTPLIQT----LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAA 248
              +V       P ++T      +  GV A  D +  G+   + E +      I L E  
Sbjct: 188 KEWVVEATKRPRPFLETAIVIASNYRGVHASIDVSD-GLGYALKELSKRSNVRIIL-EDK 245

Query: 249 LPVKPAVRGVC----ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
                 +  +C      L    LN   E  +++ ++   ++ ++  +          +IG
Sbjct: 246 PLYYKELEEICNGNTRCLWKYVLNGGEEYGVILTIDPRLSDMIIDYMKK--FRIPHKIIG 303

Query: 305 EVVERKGVRLAGLYGVKRTL 324
            V +  G+           +
Sbjct: 304 RVEQGHGLVFEKEEISIDEI 323


>UniRef50_B2UPF2 Thiamine-monophosphate kinase n=2 Tax=Verrucomicrobiaceae
           RepID=B2UPF2_AKKM8
          Length = 298

 Score =  198 bits (505), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 66/296 (22%), Positives = 102/296 (34%), Gaps = 29/296 (9%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDR-LAFSTDSYVIDPLFFPGGN---IG 73
           L+  L     +NP L         D A +   G+R L   TD  V    F PG +   IG
Sbjct: 15  LVARLLPLMPSNPSLETG---PGDDCAIIRGSGNRQLLLKTDCVVEGMHFLPGTDPELIG 71

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
           + A+    +D+   G  P +      +    P+  ++ +   M   AR  GI+I  G+  
Sbjct: 72  RKALARAVSDIGAMGGTPLHALVTLFVHADRPISQVEGIYRGMGRLARQFGISIAGGE-- 129

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
                  D L IN A  G + A       T  AGD++ V+GTLG                
Sbjct: 130 -SSGLPADGLIINVALTGEVEAGKAVLRSTARAGDLIAVTGTLGGS------------FP 176

Query: 194 GELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKP 253
                           L       ++ D +  G+   +   AAA G G  + E  LPV+P
Sbjct: 177 TGHHLSFTPRVREGGILAASGVATSMMDLSD-GLGTDLPRLAAASGLGFRIHEELLPVRP 235

Query: 254 AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVER 309
                       A+    + +L++       E+       H       +IGE+   
Sbjct: 236 GFTAA------QAVGDGEDYELLVTFRPGDRERAARLAAEHFPETPLTVIGEMTAE 285


>UniRef50_A0B852 Thiamine-monophosphate kinase n=1 Tax=Methanosaeta thermophila PT
           RepID=A0B852_METTP
          Length = 325

 Score =  198 bits (504), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 58/292 (19%), Positives = 108/292 (36%), Gaps = 21/292 (7%)

Query: 41  LDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
            D A +  +GD L  +TD    +  F        IG ++     +D+A  GA P  +   
Sbjct: 42  DDCAVVELDGDYLVVTTDMLHRETDFPDQATPWQIGWMSAAVNLSDIAAMGAEPLGVLIA 101

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
             +     +E ++ +   + +  +A G  ++ GDT   +     +L I    +G +    
Sbjct: 102 SGIPPETDLEFVEEIFEGIRDCVKAHGTEVLGGDTDAHR-----ELTICGTALGRVSRER 156

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVK 217
               +    GD+L  +G+LG  GA +  L+         + +          L     V 
Sbjct: 157 ILRRRGARPGDLLCTTGSLGGAGAGLKALKIGRIDLARRLLEPCPRVREGIALAGTGAVT 216

Query: 218 ALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLD---ALNFANEGK 274
           A+ D +  G+   +H+ A A G G  +    +P+   VR + E         L    + +
Sbjct: 217 AMMDNSD-GLALSLHDLAEAGGTGFLVECERIPIAEEVRAIAESDDEALEMVLRAGGDFE 275

Query: 275 LVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDL 326
           L++ V  +  +    A           +IG  VE  G+ L    G +  +  
Sbjct: 276 LLLTVREDMIDDARKACE-------LTVIGRAVET-GIWLE-RDGSRIPISR 318


>UniRef50_Q0APG5 Thiamine-monophosphate kinase n=1 Tax=Maricaulis maris MCS10
           RepID=Q0APG5_MARMM
          Length = 320

 Score =  198 bits (503), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 59/277 (21%), Positives = 98/277 (35%), Gaps = 11/277 (3%)

Query: 49  EGDRLAFSTDSYVIDPLFFP---GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLP 105
            G     + DS V    F        +   A+    +D+A  GA PR         E L 
Sbjct: 38  PGQETVLACDSLVAGVHFLDSDTPAVVAARALRSNLSDLAAMGARPRGYLSAIAWPEALD 97

Query: 106 METLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLT 165
               +A V ++       G+ ++ GDT          L +    +G I            
Sbjct: 98  AAWREAFVRALHREQSRYGLVLIGGDTTSTPG----PLTVTLTLVGQIETGTALRRSGAR 153

Query: 166 AGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRG 225
            G+ + VSG +GD    +L+ R+        +       P ++    + G+ +       
Sbjct: 154 PGEDVWVSGMIGDGLLGLLSARKAGTELAGALERYQAPDPRLELGLALRGLASAAIDVSD 213

Query: 226 GVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLG-LDA-LNFANEGKLVIAVERNA 283
           G+ A     AAA  C + +    +PV P  R   E  G LDA L   ++ +L+       
Sbjct: 214 GLLADAGHIAAASACSLRVDVDTVPVSPTARDWLESGGALDALLAGGDDYELLFTAPAGC 273

Query: 284 AEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV 320
            E++ A      L  +   IG V+  +GV+     G 
Sbjct: 274 RERIAAL--GLSLDTNLTRIGSVMAGEGVQARWGDGS 308


>UniRef50_C7H113 Hydrogenase maturation factor n=1 Tax=Eubacterium saphenum ATCC
           49989 RepID=C7H113_9FIRM
          Length = 347

 Score =  198 bits (503), Expect = 3e-49,   Method: Composition-based stats.
 Identities = 65/332 (19%), Positives = 122/332 (36%), Gaps = 19/332 (5%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQA-RLDLAQLVAEGDRLAFSTDSYVIDPLFFPGG 70
           G+    ++  +             +      D A +         STD     P+     
Sbjct: 13  GKLDSDILEKIVFGNIRYKSADVIKRAGLGEDCAVMDFGEYDCIVSTD-----PITATPN 67

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
            IGKLA+  + ND+A +G  P  L+   +L +G   E ++ ++    E A    + IV G
Sbjct: 68  EIGKLAVYISCNDIASNGIEPFALTMSVLLPKGTTEEEVELIMKQAGEAAMDLEVEIVGG 127

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
            T++    AV +  I +   G            ++ GD++ V+  L   G  I+    + 
Sbjct: 128 HTEITT--AVVRPVIVSTVFGKSLRGESQTCDLMSEGDLICVTKDLALEGTAIIVGDHED 185

Query: 191 GLDGELVSD----CAVLTPLIQTLRDIPGV-----KALRDATRGGVNAVVHEFAAACGCG 241
            +   L  D           I  ++D           + D T GG+   V E       G
Sbjct: 186 IMSKVLSEDEIKQAKSFMDSISVVKDGVLAGSIGTHGMHDVTEGGILGAVWEMCMNSKLG 245

Query: 242 IELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAA 301
             + E  +P+    + V + L +D L   + G +V+A+ ++    +  A      G   +
Sbjct: 246 AVIYEDEIPLNDITKKVMKYLDVDPLKMISSGSMVMAISKDKKRAMEEAFKDA--GIGFS 303

Query: 302 LIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
           +IGE+V+ K   +         +  P ++ + 
Sbjct: 304 VIGEIVDEKEGIVLKSGESSSPVSPPQSDEIY 335


>UniRef50_B4UJS8 Thiamine-monophosphate kinase n=7 Tax=Cystobacterineae
           RepID=B4UJS8_ANASK
          Length = 329

 Score =  197 bits (501), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 79/319 (24%), Positives = 114/319 (35%), Gaps = 27/319 (8%)

Query: 17  QLINSLFME---AFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGG 70
           +LI         A A   L   +D A L        G+ LA + D+ V    F   F   
Sbjct: 16  ELIERFTRALPLAGAGVRLGPGDDTALL----APPPGEDLAATVDAVVEGVHFDARFTPE 71

Query: 71  NIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTG 130
           ++G  A+    +D+A  GA P +         G P E L+ V   +   ARA  IA+V G
Sbjct: 72  DVGWKALAVNLSDLASMGARPLWALVALAFPRGTPPERLEGVARGLGACARAHRIAVVGG 131

Query: 131 DTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQL 190
           +          +L +    +GA+             GD+L+ SGT GD    +       
Sbjct: 132 NVSR-----ASELSVTVTAVGAVRRGRALLRSGARPGDLLVASGTFGDAALGLA-----P 181

Query: 191 GLDGELVSDCAVLTPLIQTLRDIPGV-KALRDATRGGVNAVVHEFAAACGCGIELSEAAL 249
           G    LV       P +   R + GV +A  D +  G+   +       G    L  AA+
Sbjct: 182 GASAALVRRQRRPAPRLALGRALAGVARAAIDVSD-GLVQDLGHLCDESGVAAVLEAAAV 240

Query: 250 PVKPAVRGVCELLGL---DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEV 306
           P   A R     L      AL    + +LV       A    A   +       A+IG V
Sbjct: 241 PTSAAYRRAARSLPDPLGPALGGGEDYELV--AALPPARLARALRAAARARVPLAVIGRV 298

Query: 307 VERKGVRLAGLYGVKRTLD 325
               GVR+ G  G +R   
Sbjct: 299 ERGSGVRILGADGAERPAP 317


>UniRef50_B5YKD2 Thiamine-monophosphate kinase n=1 Tax=Thermodesulfovibrio
           yellowstonii DSM 11347 RepID=B5YKD2_THEYD
          Length = 333

 Score =  196 bits (500), Expect = 7e-49,   Method: Composition-based stats.
 Identities = 49/339 (14%), Positives = 106/339 (31%), Gaps = 56/339 (16%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF----FPGGNIG 73
           L+  +         +         D A L  +   +  +TD  + D  F        ++G
Sbjct: 8   LVKEIRDRFSLPEDIGIG---IGDDAAVLNLKSSAIL-TTDLMIEDVHFELSYTSFYHLG 63

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
              +    +D+   G   +       + E +  +  K +   + +  +  G  ++ GD  
Sbjct: 64  FKIVSVNVSDIYAMGGDFKGFLFSAGVPETVSDQDFKELFDGIEDALKHYGGFLIGGDLS 123

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLD 193
                    + ++   +G          +   AGD++ ++  LG   A +  L      +
Sbjct: 124 RS-----KNIVLSGFAVGEAEK--PILRKGAQAGDLIFITSYLGLSSAGLNLLNNLSDDE 176

Query: 194 GELVSDCAVL---TPLIQTLRDIPGV----------------------KALRDATRGGVN 228
              +               L    G+                      KA+ D + G + 
Sbjct: 177 KRFIKSIRNFKNCKEYPDRLLKFKGINEILERHLMPIARKPDKFKHIAKAMMDISDGLLI 236

Query: 229 AVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAA 284
             +H        G E+    LP+ PA+  + + L ++     L+   + +L++  +R  A
Sbjct: 237 -DLHRLCEENKVGAEIYLDQLPIHPAITKIADYLNIEPMNPILSGGEDYELLVISDRQDA 295

Query: 285 EQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRT 323
           ++                +G +VE KG+ L      K  
Sbjct: 296 KEF-----------GLIPVGRIVEEKGIYLIDPQRGKIP 323


>UniRef50_B6QX74 Thiamine-monophosphate kinase n=1 Tax=Pseudovibrio sp. JE062
           RepID=B6QX74_9RHOB
          Length = 338

 Score =  196 bits (500), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 59/305 (19%), Positives = 102/305 (33%), Gaps = 28/305 (9%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAE-GDRLAFSTDSYVIDPLFF---PGGNI 72
            LI   F     N      +D    D A    + G  L  + D  +    FF   P   +
Sbjct: 14  SLIERYFAPLATNAGAVHLQD----DAAVFTPDTGCDLVVTKDMLMAGVHFFKNDPPFEV 69

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
            + A+    +D+A  GA P+    G  L + +  E +      +        I ++ GDT
Sbjct: 70  AQKALGVNLSDLAAKGAEPKGYLLGLGLSKEIGEEWVAEFCRGLKLVQDQFQIDLLGGDT 129

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN-----LR 187
               +G      ++    G +P           AG +L V+GT+GD    +       L 
Sbjct: 130 ISCPQG----PLLSVTAFGQVPKGQVVRRNEAVAGALLYVTGTIGDAALGLKLRLDDELA 185

Query: 188 EQLGLDGE----LVSDCAVLTPLIQTLRDIP-GVKALRDATRGGVNAVVHEFAAACGCGI 242
            +L L  E    L++   +  P +  +  +     A  D +  G+ A +           
Sbjct: 186 GELELSAEHRDFLLNRYLLPQPRVAAVSALRDYAVAAMDISD-GLIADLGHMCRTSQVQA 244

Query: 243 ELSEAALPVKPAVRGVCE---LLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKD 299
            +    +P   A   +          A+   ++ +++ AV    A     AL     G  
Sbjct: 245 AVRLENVPFSDAASAMIARDTAFRETAITGGDDYEILAAVMPENAVAFEVALQEA--GLR 302

Query: 300 AALIG 304
            A IG
Sbjct: 303 CAQIG 307


>UniRef50_C8S8T5 Thiamine-monophosphate kinase n=1 Tax=Ferroglobus placidus DSM
           10642 RepID=C8S8T5_FERPL
          Length = 301

 Score =  196 bits (499), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 54/289 (18%), Positives = 106/289 (36%), Gaps = 27/289 (9%)

Query: 41  LDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGKLAICGTANDVAVSGAIPRYLSCG 97
            D          +  + D       F        IG  A+  + +D+A  GA P Y S  
Sbjct: 18  EDAGFFKFGDAYIVIANDMLSRSFDFPSKLLPKQIGWKAVTASVSDLAAMGAKPIYFSYS 77

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
             L     +  ++ ++  + E     G+  ++GDT       +D + +  A         
Sbjct: 78  LGLSRE-EISFVEDLMKGIREALDFYGMKFLSGDTNESTELVLDSVAVGIA-------RN 129

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATIL--NLREQLGLDGELVSDCAVLTPLIQTLRDIPG 215
                    GD + V+G LG    ++L    + +   +  L      +  + + L+    
Sbjct: 130 LLLRSNAKVGDAVCVTGDLGRAYCSLLYLLEKVEEIEEKILEKFLKPVARVDEGLKLANI 189

Query: 216 VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDA----LNFAN 271
             +  D +  G++  ++  A + G  I++ E  +P++  V   C    L+     LN   
Sbjct: 190 ANSAIDVSD-GLSKELNLLANSSGVMIKVFEDRIPIREEVLEFCTSNNLNPIEVALNSGE 248

Query: 272 EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV 320
           E +L+  V ++  E +           + ++IGEV + +GV L G    
Sbjct: 249 EYELLFTVSKDKLEDL---------DFEFSIIGEVSKGEGVFLVGKEKK 288


>UniRef50_D2RZQ8 AIR synthase related protein domain protein n=1 Tax=Haloterrigena
           turkmenica DSM 5511 RepID=D2RZQ8_9EURY
          Length = 346

 Score =  196 bits (498), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 81/343 (23%), Positives = 127/343 (37%), Gaps = 31/343 (9%)

Query: 15  MQQL--INSLFMEAFANPWLAEQEDQA------RLDLAQLVAEGDRLAFSTDSYVIDPLF 66
           M  L  I+  F +    P L    D         +D   L   G  L  +TD   I P  
Sbjct: 1   MSDLGKIDRQFFDRHVAPNLGADRDDVAVGPQHGVDFGVLEIGGQALVTATDPVSIMPQL 60

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
                  + A+     DVAVSG  P +LS  F L E +  +    V  ++ E     G+A
Sbjct: 61  G-LERAARFALDLVLADVAVSGIPPSHLSICFTLPETMTDDEFATVWKTIHEECVDLGVA 119

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL 186
           +VTG T      +   +      M     +          GD LL++         +L+ 
Sbjct: 120 VVTGHTARYSDPSHPWVG-AATAMAVGDPDEIVRPDGARPGDRLLLTTGPAVESVGLLST 178

Query: 187 ----REQLGLDGELVSDCAVLTPLIQTLRD------IPGVKALRDATRGGVNAVVHEFAA 236
               + +  L G+++ D       +  +RD         V A+ D T GG+   ++E A 
Sbjct: 179 LFADQLEAALPGDVIDDAQDRLEEVYCVRDALAAAAAGPVTAMHDVTEGGLAGALNEMAD 238

Query: 237 ACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPL 296
             G    +   A+P++P V+ VC+ L +D     + G L++AV     + V+AAL     
Sbjct: 239 GAGARFSVDRDAVPMRPGVQEVCDHLEIDPWAATSSGSLLLAVAPEGVDDVVAALEDRDT 298

Query: 297 GKDAALIGEV-----VERKGVRLAGLYGVKRTLDLPHAEPLPR 334
               A IG V      +  G  +         L  P  +P  R
Sbjct: 299 VV--AEIGRVEEPSGTDGDGEVVVDGD----RLPHPSVDPSWR 335


>UniRef50_Q7UPP0 Thiamine-monophosphate kinase n=1 Tax=Rhodopirellula baltica
           RepID=Q7UPP0_RHOBA
          Length = 316

 Score =  195 bits (497), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 64/300 (21%), Positives = 91/300 (30%), Gaps = 35/300 (11%)

Query: 25  EAFANPWLAEQEDQARLDLAQLVAEGD---RLAFSTDSYVIDPLFFPGG----NIGKLAI 77
                  +   +D A +D    V+      R    TD  +    F        +IG  A+
Sbjct: 14  RQLPQVAVGIGDDAAVIDWPGSVSSDQPQLRQVACTDQILDGVDFRSEEQSLSDIGFKAM 73

Query: 78  CGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQR 137
               +D+A  GA P        L      E    V   + E A+   +AI  GD      
Sbjct: 74  AINLSDIAAMGATPSSALVTLALPAENATEIAGEVYEGILEAAQKYQVAIAGGDLSTYDG 133

Query: 138 GAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELV 197
                L I+   +G       W       GD L V+G LG                    
Sbjct: 134 ----PLSISITILGWTE--QPWLRTGAEEGDALFVTGALGGSLLGRHL------------ 175

Query: 198 SDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRG 257
                   L   L+    V A  D +  G +  +    AA   G EL    LP+  A   
Sbjct: 176 -RPEPRVELAAKLKQTVNVHAAIDVSD-GFSLDLDRMLAASRMGAELELETLPISEAAHQ 233

Query: 258 VCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVR 313
             E  G   L        + +L+  V    A    A + S   G     +G+VV R G+ 
Sbjct: 234 FAEKSGRTPLEHAWSDGEDFELIFCVAPEEA----AIIESTDWGVPVTRVGKVVGRTGLW 289


>UniRef50_C1F3W9 Thiamine-phosphate kinase n=1 Tax=Acidobacterium capsulatum ATCC
           51196 RepID=C1F3W9_ACIC5
          Length = 338

 Score =  195 bits (496), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 63/329 (19%), Positives = 94/329 (28%), Gaps = 37/329 (11%)

Query: 33  AEQEDQARLDLAQLVA-EGDRLAFSTDSYVIDPLFF----PGGNIGKLAICGTANDVAVS 87
           A        D A L    G  +  +TD  +    F        + G   +    +D+A  
Sbjct: 20  AGVRVGIGDDCAVLRPRAGHEIVVTTDLLLEGTHFRRDWHSPESAGHRCLARGLSDLAAM 79

Query: 88  GAIPRYLSCGFILEEGL-------PMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAV 140
           GA P                        L   +  +   A A G+++  GDT     G V
Sbjct: 80  GASPLAAFLSLAAPPERMRPQGRAKKSWLDRFLDGLLALADAHGVSLAGGDTAQSPMGGV 139

Query: 141 DKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL-----DGE 195
                +   +G  P           AGD L V+G LG   A +L L     L        
Sbjct: 140 ---IADIVLLGQTPRGRALLRSGARAGDRLYVTGALGGAAAELLALGHGQSLRLKGATAH 196

Query: 196 LVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAV 255
                     + Q L       A  D +  G++  +       G    +  AALPV P  
Sbjct: 197 PQLFPQPRLAVGQRLLGARLATAAIDISD-GLSTDLDHLCEESGLAAVIDAAALPVHPLA 255

Query: 256 RGVCELLGL-----DALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVE-- 308
               E          AL+   + +L+            A +     G     IG +    
Sbjct: 256 VMAAERGWAASAQGLALHGGEDYELLFTAAPA------ARVPRQIAGVPVTCIGAMQAPA 309

Query: 309 --RKGVRLAGLYGVKRTLDLPHAEPL-PR 334
             +  ++L    G    L     E   PR
Sbjct: 310 RRQPRMQLRSAGGSSEALAPGGWEHFRPR 338


>UniRef50_C8WEQ3 Thiamine-monophosphate kinase n=5 Tax=Sphingomonadaceae
           RepID=C8WEQ3_ZYMMN
          Length = 321

 Score =  194 bits (495), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 57/298 (19%), Positives = 108/298 (36%), Gaps = 21/298 (7%)

Query: 31  WLAEQEDQAR---LDLAQLVAEGDRLAFSTDSYVIDPLFFP---GGNIGKLAICGTANDV 84
                +  AR    D A L      L  S D  V +  +FP      + +  +    +D+
Sbjct: 13  RQIAGDPAARNLSDDAAVLPRPSGDLVLSHDIIVENVHYFPSDPPETVAQKLVGVNLSDL 72

Query: 85  AVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLF 144
           A  GA P     G+ L      +  +A +  +        + ++ GDT  V R      F
Sbjct: 73  AAKGAKPIGALMGYSLGPDY--KWDQAFLKGLESVCHQYNLPLLGGDTVAVPRHTGH--F 128

Query: 145 INTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL----DGELVSDC 200
                +G  P+      +    GD L V+  +GD G  +  L+++  +      +LV   
Sbjct: 129 SAMTVIGLAPSCGVPDRRAAKEGDELWVTSPIGDAGFGLNLLKQKKNINHSAQEKLVQAY 188

Query: 201 AVLTPLI-QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGV- 258
               P + + +   P V A+ D + G +       A A G  + +    +P+        
Sbjct: 189 RSPEPRLKEGIWLAPHVHAMADISDGLLIDA-ERIANASGLAVRIRLDRVPLSSEAISCF 247

Query: 259 --CELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL 314
              +   L A+   ++ +L++A   N  +++L          D   +G++    G+ L
Sbjct: 248 GDTKSTRLQAVTAGDDYQLIMACAANKRQELLKLSKEKQF--DLYRVGQLTAGSGLSL 303


>UniRef50_C6CVI9 Thiamine-monophosphate kinase n=1 Tax=Paenibacillus sp. JDR-2
           RepID=C6CVI9_PAESJ
          Length = 349

 Score =  194 bits (495), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 57/304 (18%), Positives = 105/304 (34%), Gaps = 31/304 (10%)

Query: 30  PWLAEQEDQARLDLAQLVAEGD---RLAFSTDSYVIDPLF----FPGGNIGKLAICGTAN 82
             L   +D A +D A  +   D       + D+ V    F        +IG  A+    +
Sbjct: 25  VRLGIGDDAALVDPAAPINGVDSPYEYIMAMDTMVETVHFNEVTMSYEDIGYKALASNVS 84

Query: 83  DVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDK 142
           D+A  G +P        + + L  E +  +   +   A   G+A++ GDT    +  V  
Sbjct: 85  DIAAMGGVPLQALVSVSVPKQLGPEPMHRLYDGLYACAEQYGVAVIGGDTTSSPQHLVVA 144

Query: 143 LFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI----------LNLREQLGL 192
           + +      A+ A           GD ++++G +G   A +           +       
Sbjct: 145 VTVTG----AVEAGKALRRSGAKPGDAVVLTGPVGKSAAGLHFLLAQRERGADALAGERA 200

Query: 193 DGELVSDCAVLTPLIQT---LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAAL 249
             +LV      +P ++    L       +L D +  G+ +   E A A G  + L E  L
Sbjct: 201 AAQLVQAHRRPSPSVRAGRLLLARGTCHSLNDVSD-GLASEAWEIAEASGLVVSLFEKHL 259

Query: 250 PVKPAVRGVCELLGLDALNF----ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGE 305
           P   ++     + G+D L +      +  L+  +     +   A    H  G    +IGE
Sbjct: 260 PRSGSMAAYAGVAGIDPLEWMLYGGEDYVLLGTM--EQGDAAAAQAAFHAEGLPFYIIGE 317

Query: 306 VVER 309
               
Sbjct: 318 ASAG 321


>UniRef50_A6GU77 Thiamine monophosphate kinase n=1 Tax=Limnobacter sp. MED105
           RepID=A6GU77_9BURK
          Length = 358

 Score =  194 bits (495), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 58/352 (16%), Positives = 101/352 (28%), Gaps = 54/352 (15%)

Query: 17  QLINSLFMEAFAN---PWLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFP---G 69
            LI+  F   F                 D A L +  G  L  STD+ V    FF     
Sbjct: 4   DLIHRYFKTPFGRLARANANTVLVGIGDDCATLQLLPGHHLYTSTDTLVEGVHFFSDDSP 63

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
              G  A+    +D+A SGA P   +    L E +    L      + + A      +V 
Sbjct: 64  HATGWKALACNLSDLAASGASPLGFTLNLSLPE-INESWLADFSAGLLDVATRFNCPLVG 122

Query: 130 GDTKVVQRGAVDKLFINTAGMGAIP-ANIHWGAQTLTAGDVLLVSGTLGDHGATILNLRE 188
           GDT     G      ++    G  P  +  +       G+ + +SGT G     +L   +
Sbjct: 123 GDTTSS--GPNPSKTLSITVFGQAPITHRGFNRAHAKIGEEVWLSGTPGLARLGLLLEYQ 180

Query: 189 QLGLDGE-------------------------LVSDCAVLTPLIQTLRDIPGVKALRDAT 223
           +     E                         ++     L  L   +R      A  D +
Sbjct: 181 RRDRLAECCQGTELHQVQVLLDAMPAHLRQSAVIQLGTPLPRLELGVRLHGLASACLDLS 240

Query: 224 RGGVNAVVHEFAAACGCGIEL--------SEAALP---VKPAVRGVCELLGLDALNFANE 272
             G++  +   + A      L             P    +     + ++L    L   ++
Sbjct: 241 D-GLSGDLAHISKASDVSAVLVQSSLESMWRERWPEICQRADAAELLKILVTQTLKGGDD 299

Query: 273 GKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTL 324
            +L      N  + +         G     +G +    G+ L      +  +
Sbjct: 300 FELCWTAHPNHHDAI------QSFGGGLHCVGFIEPGSGIWLQSPSADRTRV 345


>UniRef50_UPI000038DF5E AIR synthase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI000038DF5E
          Length = 343

 Score =  194 bits (494), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 69/339 (20%), Positives = 126/339 (37%), Gaps = 28/339 (8%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQA------RLDLAQLVAEGDRLAFSTDSYVIDPLFFP 68
           M   I+  F E      +    D+        +D+  +      +A +TD   ID  F  
Sbjct: 1   MIGKISRKFFEENIINKIGTLRDEVVVPPKNGVDVGIVKIGDKYMAVTTDPLYIDKSFG- 59

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
                  A     +D+  SG    Y+S    L   +     K +   + E      I +V
Sbjct: 60  FKKAAWFAFHILLSDLYTSGIPASYMSIDLNLPSSITDNEFKEIWDVINEECIKYNIEVV 119

Query: 129 TGDTKVVQRGAVDKLFIN-TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILN-- 185
           TG T       V+   +     MG          +    GD ++++ +     A IL+  
Sbjct: 120 TGHTARY--NGVEFPMVGGITLMGTGEK--FITTENAGVGDRIIMTKSCALETALILSNT 175

Query: 186 ----LREQLGLDG--ELVSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEF 234
               +R  +G +    ++     +T + +    I       + ++ DAT GG+   ++E 
Sbjct: 176 FPEYVRNNIGEENYKSIIGKFYTMTCVGEETLAIEYGISERITSMHDATEGGLLNAIYEI 235

Query: 235 AAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSH 294
             A G G+ +    + +   +  +C L  +D L   +EG L+I V+   A + L  L S 
Sbjct: 236 GIASGNGLSVDYNKIIIDSDIEKLCNLFNIDPLRSISEGTLLITVKEQYAMEFLTILQS- 294

Query: 295 PLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
             G +A+LIGE+++          G +  +  P  + L 
Sbjct: 295 -SGIEASLIGEILDNSKGIKILKDGKQEDI-RPEDDQLW 331


>UniRef50_A5UMR0 Thiamine monphosphate kinase, ThiL n=3 Tax=Methanobrevibacter
           smithii RepID=A5UMR0_METS3
          Length = 306

 Score =  194 bits (494), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 49/293 (16%), Positives = 96/293 (32%), Gaps = 32/293 (10%)

Query: 41  LDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNIGKLAICGTANDVAVSGAIPRYLSCG 97
            D A        L  + D  +    F        +G  ++    +D+A  GA P      
Sbjct: 27  DDTAVTPIANTNLISTCDMLIQSKHFPENMSYFQMGFKSVTVNVSDLAAMGATPLGFLLS 86

Query: 98  FILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANI 157
             L +   ++  K ++  + +     GI ++ GDT         ++ I+   +G    + 
Sbjct: 87  IALPKDFEVDDFKQIIKGVLKACEYYGICLIGGDTN-----EASEIIISGTALGLC--DN 139

Query: 158 HWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIP--G 215
                T   GD+++++G +G            L  D             I+   +I   G
Sbjct: 140 PLMKNTSEKGDLVVLTGKIGLAALGF-----NLENDNIYTKKALEPIAKIKEGINIKNSG 194

Query: 216 VKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCEL----LGLDALNFAN 271
             +  D T  G+ + ++E       G  + E  L +    + +            L+   
Sbjct: 195 GTSATDITD-GLASELYEM-KREDIGFMIYEDKLDISGEFKSLAAELNLNYLDLLLHVGE 252

Query: 272 EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTL 324
           + +LV  + +            H L     +IGEV + K V +       R +
Sbjct: 253 DFELVFTINKKNL---------HKLNFKYLVIGEVTDSKKVEIRLSDSTVRQI 296


>UniRef50_C4ZI96 Hydrogenase expression/formation protein n=1 Tax=Eubacterium
           rectale ATCC 33656 RepID=C4ZI96_EUBR3
          Length = 333

 Score =  194 bits (494), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 58/338 (17%), Positives = 129/338 (38%), Gaps = 24/338 (7%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQ-EDQARLDLAQLVAEGD---RLAFSTDSYVIDPLFF 67
           G+  + ++    ++           +     D A +  +     +L  +T ++ +D    
Sbjct: 4   GKISESVLKRSVLKQLHTKSDRILFKPAVGEDCAVISMQAGGKTKLVTATQTFTLDV--- 60

Query: 68  PGGNI-GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
              ++    A+    N++   GA P  +    ++        L+  V ++      AGI 
Sbjct: 61  SDKHVRANCAVYDALNNIYAMGADPVGIELALLVPTTENEAVLRETVRAIDAVCEKAGIV 120

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL 186
           ++ G T+V +  AV  + +    +G         +     G  ++V+G +G  G  IL  
Sbjct: 121 VLGGHTQVSR--AVKNIVVTVTAIGEAYEQALTPSSAAAPGMDVIVTGYVGLEGTAILAN 178

Query: 187 REQLGLDGEL----VSDCAVLTPLIQTLRDIP-----GVKALRDATRGGVNAVVHEFAAA 237
            ++  L+       +   A     I T  +       GV A+ DA++GG+   + + A A
Sbjct: 179 EKRTELETRFSKAFIDKSAAYIDHISTAMEAASAIGAGVAAIHDASQGGIFGALWDMAEA 238

Query: 238 CGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLG 297
            G G+++    LP++     + E   ++     + G L+I        +V+  L     G
Sbjct: 239 SGIGLDIDLKKLPIRQDTIEISEFFDINPYKLLSGGSLIIIAA--DGTRVVRELEK--TG 294

Query: 298 KDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRI 335
           ++A ++G   +     L      +R L+    + + ++
Sbjct: 295 QNAVIVGATTDSNDRVLISGE-ERRFLETAQTDEIYKV 331


>UniRef50_B8D6Q8 AIR synthase related protein domain protein n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D6Q8_DESK1
          Length = 331

 Score =  194 bits (493), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 58/333 (17%), Positives = 117/333 (35%), Gaps = 20/333 (6%)

Query: 12  GQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGN 71
           G+    ++N       +             D A +  +   L    D     P+      
Sbjct: 5   GKFSWSIMNRFLSLLPSMDPDLVIGPMQGEDAAVIRFKDGFLVTHVD-----PITTGVKK 59

Query: 72  IGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGD 131
            G LA+   +ND+AV G  P++     ++     +E  + + + M +         + G 
Sbjct: 60  AGYLAVHVASNDIAVRGVTPKWFMPVVLIPRHYSVEEAEELFSDMGKALSEIHGVAIGGH 119

Query: 132 TKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLG 191
           T+V     +D+  I    +G          +    GD ++V G +G  GA ++       
Sbjct: 120 TEVTP--GLDRPIIAMTVIGYTN-GRVISTRDAGEGDYVVVIGRIGGEGAGVIAWDFGDK 176

Query: 192 L----DGELVSDCAVLTPLIQ----TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIE 243
           L      +++         +      L     V  + DAT GG+   + E A+A    I 
Sbjct: 177 LLGKVPRDVIEHARSFIYDVSIVKTALAIKDYVNTMHDATEGGILQALREVASASKKDIV 236

Query: 244 LSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
           + + A  +   V+ +   + +D L   + G +V  V     + +L  L  H  G   +++
Sbjct: 237 VLDKAFYIDEEVKRITSAVNVDPLRLLSSGCIVATVAPGYLDSLLNELKKH--GIRHSVV 294

Query: 304 GEVVERKGVRLAGLYGVK--RTLDLPHAEPLPR 334
           G V   +G  +      +    +D    + + +
Sbjct: 295 GRVTRGEGRVIIKGDSGETITIIDSDITDEIYK 327


>UniRef50_B0R9W2 Hydrogenase expression/formation protein n=3 Tax=Halobacteriaceae
           RepID=B0R9W2_HALS3
          Length = 340

 Score =  194 bits (493), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 88/329 (26%), Positives = 132/329 (40%), Gaps = 25/329 (7%)

Query: 19  INSLFMEAFANPWLAEQEDQA------RLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNI 72
           I++ F     +P L   +D         +D   L   G RL  S D   ++P        
Sbjct: 8   IDAEFFAQHLSPNLGADDDAVTVGPQYGVDFGVLSIGGQRLVVSADPVSVNPGVG-IERA 66

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           G+LA+    +DVAVSG  P +LS   +L      +T+ A+  +MA      G+++VTG T
Sbjct: 67  GRLALHSVLSDVAVSGVPPSFLSITLVLPASARDDTIAALWDAMATECERLGVSVVTGHT 126

Query: 133 KVVQRGAVDKLFINT-AGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQ-- 189
                  V   +I     MG             TAGD +L++ + G   A +        
Sbjct: 127 ARQD---VSFPWIGGATAMGVGDPAEIVRPDGATAGDTVLMTHSPGAEVAGLFAALFGDH 183

Query: 190 LGLDGELVSDCAVLTPLIQTLRDIPG-----VKALRDATRGGVNAVVHEFAAACGCGIEL 244
           L +  + V            + D        V A+ DAT  G+   + E A A G  I +
Sbjct: 184 LDVADDTVERADARLEDTTVVGDACAAASAPVTAMHDATECGIQGALVELATAAGVSISV 243

Query: 245 SEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
           S  A+PV   V  VC  LGLD    ++ G L++ V    A+  +AAL +       A IG
Sbjct: 244 SSDAVPVPEDVSAVCADLGLDPWQVSSRGTLLVTVPEAHADTAMAALDAR--NTPVAAIG 301

Query: 305 EVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
            V E  GV + G       +  P ++P  
Sbjct: 302 TVSEGSGVTVDGTQ-----VVHPGSDPAW 325


>UniRef50_A4A6E1 Thiamine monophosphate kinase n=2 Tax=unclassified
           Gammaproteobacteria RepID=A4A6E1_9GAMM
          Length = 310

 Score =  194 bits (493), Expect = 4e-48,   Method: Composition-based stats.
 Identities = 67/323 (20%), Positives = 110/323 (34%), Gaps = 38/323 (11%)

Query: 11  GGQAMQQ---LINSLFM--EAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPL 65
           GG+  +    LI       +      +   +D A L L       + L  S DS +    
Sbjct: 3   GGKQPRDEFSLIARYLKELDRGPAVVVGNGDDGAVLRLDAH----EELVVSVDSMLEGVH 58

Query: 66  F---FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARA 122
           F    P   +   A+    +D+A  GA P  ++    + E      L+ +   +++    
Sbjct: 59  FPFDSPPSELAYRAVAAATSDLAAMGARPLGMTLALTIPEA-DDAWLRELRLGLSDAVGD 117

Query: 123 AGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGAT 182
             + +V GD           L ++   MGA+PA           GD + VSG LGD  A 
Sbjct: 118 FSLPLVGGDLTRGS------LTLSVQVMGAVPAGGAIRRDGARPGDRVCVSGPLGDAAAG 171

Query: 183 ILNLREQLGLDGEL-----VSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAA 237
           +  +  ++  DG             +  L   +       A  D +  G+ A +   A A
Sbjct: 172 LALIEGRVAGDGPANTALREHFWRPMPALDLGISLRGKATAAVDVSD-GLLADLGHIAEA 230

Query: 238 CGCGIELSEAALPVKPAVRGVC--ELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
               + +  + LP+  AV  +   E     AL    +  L   +             SH 
Sbjct: 231 SKVCVIVDSSQLPISEAVNSIASGEQALAWALGGGEDYCLGFTLP-----------ESHE 279

Query: 296 LGKDAALIGEVVERKGVRLAGLY 318
           L   + +IG V E  GVR     
Sbjct: 280 LPPGSCVIGRVEEGAGVRCDAAD 302


>UniRef50_A3UCC4 Thiamine-monophosphate kinase n=1 Tax=Oceanicaulis alexandrii
           HTCC2633 RepID=A3UCC4_9RHOB
          Length = 336

 Score =  194 bits (493), Expect = 5e-48,   Method: Composition-based stats.
 Identities = 53/302 (17%), Positives = 102/302 (33%), Gaps = 23/302 (7%)

Query: 21  SLFMEAFANPWLAEQEDQARLDLAQL--VAEGDRLAFSTDSYVIDPLFF---PGGNIGKL 75
                  A   +         D   +    EG   A + D+ V    F          + 
Sbjct: 13  EYIRSRLAPLSVGLPGAANLTDDGAVLSPPEGCEWAITADTLVEGRHFPLREDPALAARK 72

Query: 76  AICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVV 135
           A+    +D+A  GA P       +  E      +      +A      G+ +  GDT   
Sbjct: 73  ALRVNLSDLAAMGADPHAYLACVVWPETGREARMTGFADGLALDQAEFGVHLAGGDTTSA 132

Query: 136 QRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGE 195
                    I+    GA+P            GDV +++GT+GD G  +L  + +   + +
Sbjct: 133 DGPW----MISITAFGAVPTGQAVRRAGAKPGDVAILTGTIGDAGLGLLVRQGEYAPNQD 188

Query: 196 LVSDCAVLTPLIQTLRDI-----PGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALP 250
             +       L +    +         +  D +  G+ +     A A G  + L    +P
Sbjct: 189 DAAYLDQRFTLPEPRCALSSLVRSFAHSAIDISD-GLLSDARHIAHAAGVSLTLDLDKMP 247

Query: 251 VKPAVRGVC--ELLGLDAL----NFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIG 304
              A       +    +AL    +  ++ +L++ + ++ A+  + A+    LG  A+ +G
Sbjct: 248 RSEAAEAWLSRQADRDEALMTLASMGDDYELLVTIPQDRAQAFIEAVQ--VLGVQASRLG 305

Query: 305 EV 306
           EV
Sbjct: 306 EV 307


>UniRef50_B4WRX3 AIR synthase related protein, C-terminal domain n=1
           Tax=Synechococcus sp. PCC 7335 RepID=B4WRX3_9SYNE
          Length = 329

 Score =  193 bits (490), Expect = 9e-48,   Method: Composition-based stats.
 Identities = 45/292 (15%), Positives = 82/292 (28%), Gaps = 23/292 (7%)

Query: 34  EQEDQA----RLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGA 89
              D +      D A +      L  + +      +       G  A+    +D+A  G 
Sbjct: 36  PGVDGSQIRLGDDCAAIFDGDGYLLLAAEGIWPQLVLSDPWFAGWCAVMVNLSDIAAMGG 95

Query: 90  IPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAG 149
               +            E  + +   M   A A G+ IV G T      +     +  A 
Sbjct: 96  SAIAVVDALW---SRSQEETQQIWAGMRAAATAYGVPIVGGHTNCHSEYSG----LAVAV 148

Query: 150 MGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQT 209
           +G    +    +   + GD L++   +   G    +            +        +  
Sbjct: 149 LGRA--SQLITSFEASPGDTLMMV--INMAGVYYGDYPFWNAATMAEPAMLRSHLSKLTD 204

Query: 210 LRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNF 269
           L +     A +D + GG+   +     A GCG  L    +P    V           L  
Sbjct: 205 LANANLCSAGKDISMGGLAGTLLMLCEASGCGALLDLNRVPRPVGVPWTK------WLTS 258

Query: 270 ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVK 321
                 +++V  N    V     S+        +GE+     V L      +
Sbjct: 259 FPSYGFLLSVPPNNVAAVKRLFASNQ--VVCQTVGEITPMTSVVLQLQDERR 308


>UniRef50_Q6KZH8 AIR Synthase n=1 Tax=Picrophilus torridus RepID=Q6KZH8_PICTO
          Length = 334

 Score =  192 bits (489), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 69/338 (20%), Positives = 137/338 (40%), Gaps = 32/338 (9%)

Query: 15  MQQLINSLFMEAFANPWLAEQEDQA------RLDLAQLVAEGDRLAFSTDSYVIDPLFFP 68
           M   I+  F E+     L    D+        +D+  +      LA +TD + IDP+F  
Sbjct: 1   MTGKISREFFESNIIKRLGFLRDEVVVPPENGVDVGIVRLGNGYLAVTTDPFYIDPVFG- 59

Query: 69  GGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIV 128
                        +D+  SG    Y+S    L + +  +    + T + + ++   + +V
Sbjct: 60  LKKAAWFGFHILLSDIYTSGIPAMYMSIDLNLPQSMSDDEFNEIWTVINDESKKYNVMVV 119

Query: 129 TGDTKVVQRGAVDKLFIN-TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLR 187
           TG T       V    I     MG    + +   +    GD+++++ T     + IL+  
Sbjct: 120 TGHTARY--AGVSYPMIGGVTLMGY--GDRYITTKNAGDGDIIIMTKTCALEASCILSYT 175

Query: 188 EQLGLDGEL-VSDCAVLTPLI-------QTLR----DIPGVKALRDATRGGVNAVVHEFA 235
               ++  L +     L  L        + +      +  + ++ DAT GG+   ++E  
Sbjct: 176 FPEYIEKHLGMDTLKKLNDLFYKMTCVNEEILSIDFGLDKITSMHDATEGGIINALYEIG 235

Query: 236 AACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHP 295
            A G G+ +++  + +  +V  V +L  +D L   +EG L+I V+RN A+++L  L S  
Sbjct: 236 KASGHGVIVNKNNINIDESVSRVTKLFNIDPLRSISEGTLLITVKRNFADELLLKLRSA- 294

Query: 296 LGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
            G D+ +IGE+ +   ++          +  P  + + 
Sbjct: 295 -GIDSYIIGEL-KGDEIKFDTGE-----MIKPGDDQIW 325


>UniRef50_B1I654 Selenide, water dikinase n=1 Tax=Candidatus Desulforudis
           audaxviator MP104C RepID=B1I654_DESAP
          Length = 319

 Score =  192 bits (489), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 64/311 (20%), Positives = 105/311 (33%), Gaps = 35/311 (11%)

Query: 30  PWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGA 89
           P +  +    R D A +   G  LA       I P+       G++A     +D+   G 
Sbjct: 7   PLVDPRILAGREDDAAVYRVGPDLALIQTVDYITPVVDDPYTFGQVAAANALSDIYAMGG 66

Query: 90  IPRYLSCGFILE-EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTA 148
            P +         + +P+  L+ ++   A+ A  AG++I  G                  
Sbjct: 67  RPVFALNIVGFPNQSIPLGILEDILRGGADKAAEAGVSIAGGH-----SITDHAPKYGLC 121

Query: 149 GMGAIPANIHWGAQTLTAGDVLLVSGTLGDH--GATILNLREQLGLDGELVSDCAVLTPL 206
             G              AGDVL+++  LG       I       GL+   V     L   
Sbjct: 122 VTGFAHPERLVFRSGARAGDVLVLTKPLGTGVIATGIDRRLVDAGLETLAVRYMTALNRE 181

Query: 207 IQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVC------- 259
              +    GV A  D T  G+   + E AAA G G+E+  + +PV P    +        
Sbjct: 182 AAEVMLRIGVHACTDVTGFGLLGHLWEMAAASGVGVEVEASRVPVIPGALELARAGAVAG 241

Query: 260 ----------ELLGLDALNFAN----------EGKLVIAVERNAAEQVLAALHSHPLGKD 299
                     E    +                 G L++AV  +  + +LAAL      ++
Sbjct: 242 GAHGNYRYARERYRWEPSLSEEMRLVLCDPQTSGGLLMAVAPDKLDALLAALRGAAGAEE 301

Query: 300 AALIGEVVERK 310
           +A+IG +V   
Sbjct: 302 SAVIGRLVRDP 312


>UniRef50_Q6AQZ8 Related to hydrogenase expression/formation protein (HypE) n=1
           Tax=Desulfotalea psychrophila RepID=Q6AQZ8_DESPS
          Length = 345

 Score =  192 bits (488), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 75/335 (22%), Positives = 131/335 (39%), Gaps = 18/335 (5%)

Query: 12  GQAMQQLINSLFMEAFANP-WLAEQEDQARLDLAQL-VAEGDRLAFSTDSYVIDPLFFPG 69
           G+     + +L   A   P           LD A L  A+G  +A + D     P   P 
Sbjct: 8   GKPSPSRLQALVQGALGKPCKSLLVGPGPGLDAAILQTADGRVMAIAEDPIFPAP-GLPL 66

Query: 70  GNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVT 129
             +G   +   A+D+AV+G  P +++   +L  G P E  + +++S++  A   GI+IV 
Sbjct: 67  DIMGWFTVHIGASDIAVTGVKPEFMTYTLLLPLGCPEEDARTIISSISRAAEDLGISIVG 126

Query: 130 GDTKVVQRGAVDKLFIN-TAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATIL---- 184
           G T     GAV    +      G    +          GD++L++       A +L    
Sbjct: 127 GHTGWY--GAVTVPTVGGVTVWGTADQDAWISPGGAKDGDLILMTKGPCIEAAALLSIVH 184

Query: 185 NLREQLGLDGELVSDCAVLTPLIQTLRDI------PGVKALRDATRGGVNAVVHEFAAAC 238
           + R Q  +  E+++        I  + D        GV A+ DAT GGV   + E + + 
Sbjct: 185 HERLQGNISEEMLATLRARVDQITVVEDALHAFKVGGVHAMHDATEGGVQGGLWEMSTSS 244

Query: 239 GCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
           G  + +    + +   +  +   L  D     +EG L+ AVE    ++V        LG 
Sbjct: 245 GLPVMVDFDGVEIPADIVALARELDFDPWQAISEGTLLAAVEPEQVQEVQRVW--ADLGI 302

Query: 299 DAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLP 333
           D+ ++G+             G  + L  P ++P  
Sbjct: 303 DSYILGKFDSSLKENTVLKNGQSQPLLEPDSDPFW 337


>UniRef50_A4BAR6 Thiamine monophosphate kinase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BAR6_9GAMM
          Length = 313

 Score =  191 bits (487), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 55/315 (17%), Positives = 100/315 (31%), Gaps = 19/315 (6%)

Query: 18  LINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNIGK 74
           LI   F              Q+  D   + +    L  S D+ V    F        + +
Sbjct: 6   LIQRCFQ---GWDITHPNVLQSIGDDCLVWSGSQPLVVSADTAVAGRHFPEWASPEQVAQ 62

Query: 75  LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV 134
            A     +D+A   A P + +    L      + L      +   A   GI +  GD   
Sbjct: 63  RAFLPAVSDLAAMTATPAFFTLALTLPPATSEDWLTRFALRLRALAETYGIMLAGGD-TT 121

Query: 135 VQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI---LNLREQLG 191
                   L ++                   +GD + V+G LG   A +   L  RE   
Sbjct: 122 AGATLTLTLSVHGTC------PHPVLRSGARSGDQIWVTGQLGQSAAALPYILEKREADA 175

Query: 192 LDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
                 +      P++   +    + +  D +  G+       A A  C + +    LP+
Sbjct: 176 PRSWSEAYWNPQPPVLFASQLQGCIHSAIDLSD-GLIGDAAHLARASECDLAIHLDRLPL 234

Query: 252 KPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKG 311
           +  ++   +     AL   ++ +L+   +  A  +++A   +         IGEV   KG
Sbjct: 235 ENDLKQREDEGLKLALAGGDDYQLLFTADPVAEREIVAL--AAQAQVSVTKIGEVQAGKG 292

Query: 312 VRLAGLYGVKRTLDL 326
                  G++R L  
Sbjct: 293 DIRWYDSGLERQLPW 307


>UniRef50_C6XIX6 Thiamine-monophosphate kinase n=1 Tax=Hirschia baltica ATCC 49814
           RepID=C6XIX6_HIRBI
          Length = 323

 Score =  191 bits (485), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 57/321 (17%), Positives = 100/321 (31%), Gaps = 23/321 (7%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGGNIG 73
            LI + F     +P     +D      A     G +L  +TD+ V    F    P   + 
Sbjct: 5   DLIKTYFAPLAISPDAFGLKDDV---AALNPPAGRQLIITTDTLVESVHFLSEDPLETVA 61

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
           +  +    +DV   G  P           G  +  L +    +       GI+++ GDT 
Sbjct: 62  QKLLRVNISDVLAKGGTPWAAVLSLTWPSGRDVRQLSSFADGLKADLEHWGISLMGGDTT 121

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL- 192
                    L +        P            GD + V+G++GD    +     +L L 
Sbjct: 122 STSGPLTLGLTLLAHC----PQTGPILRSGGKQGDDIWVTGSIGDGYLGLKAAMGELSLS 177

Query: 193 --DGELVSDCAVLTPLIQTLRDIPGV----KALRDATRGGVNAVVHEFAAACGCGIELSE 246
             +   +       P I        +     A  D +  G+ A ++  A A      ++ 
Sbjct: 178 RPEDVALLAWRYRVPEIPDSAIAELISEVAHASADVSD-GLVADINHIAKASNLQAIINL 236

Query: 247 AALPVKPAVRGVCELLGLDALNF---ANEGKLVIAVERNAAEQVLAALHSHPLGKDAALI 303
             +P   A +       +  L      ++ + V      A   +L A  S   G +   I
Sbjct: 237 DEVPFSSAAKLCLAEKKVSRLELVTKGDDYQSVFTAPPEAKAVILRA--SLQYGLEITKI 294

Query: 304 GEVVERKGVRLAGLYGVKRTL 324
           G +   +GV L    G    +
Sbjct: 295 GTMQTGQGVSLQRPNGTMIPI 315


>UniRef50_UPI00003C83B8 thiamine monophosphate kinase n=1 Tax=Ferroplasma acidarmanus fer1
           RepID=UPI00003C83B8
          Length = 322

 Score =  191 bits (485), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 54/310 (17%), Positives = 102/310 (32%), Gaps = 19/310 (6%)

Query: 16  QQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF---FPGGNI 72
           + L     ++   +     +    R D A +         STD    +            
Sbjct: 4   KDLGERKIIQTLED---GSKNLDNRDDCAIIGFGNYYALLSTDLITRETHLPEGAEPFLA 60

Query: 73  GKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDT 132
           GK       +D+A    IP        +     +  L+     +        ++I+ GDT
Sbjct: 61  GKFFAAINLSDIAAMAGIPSGFLISLSVSPEYDISYLEEFYRGVRHELDKFNVSIIGGDT 120

Query: 133 KVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGL 192
           K                +G     +      +  G  L+V+ +LG   A  +     +  
Sbjct: 121 KEGSDFTA-----AGTIIGKQVPELIRRRSEIKPGQFLMVTNSLGSSAAGYIYYMYGINR 175

Query: 193 DGELVSDCAVLTPLIQTLRD-IPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPV 251
           +  +     V   + + ++    G K + D +  GV A +H+ +   G G +L    +P 
Sbjct: 176 ELGIRKMLDVEPRINEAIKISASGAKFMMDLSD-GVYASIHQISTDFGVGFKLYGDKIPF 234

Query: 252 KPAVRGVCELLGLD----ALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVV 307
              V     +        AL+F  + +L+  VE+N+ E+ +AA+       +   IGE  
Sbjct: 235 DRDVEKAASISNFSVSDIALSFGGDYELMFTVEKNSLEEFMAAMSHE--NIEVHCIGETY 292

Query: 308 ERKGVRLAGL 317
               V   G 
Sbjct: 293 NGDNVIYDGR 302


>UniRef50_C8W2B7 Selenide, water dikinase n=8 Tax=Bacteria RepID=C8W2B7_DESAS
          Length = 344

 Score =  190 bits (483), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 63/313 (20%), Positives = 101/313 (32%), Gaps = 41/313 (13%)

Query: 32  LAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIP 91
           +  +    R D A +    + LA       I P+       G +A     +D+   GA P
Sbjct: 34  VDPKVLAGREDNAAVYKVSNDLAVVQTVDYITPVVDDPYQYGMIAAANAISDIYAMGATP 93

Query: 92  RYLSCGFILE-EGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGM 150
            +         + LP+  L  ++   A+ A  AGIAI+ G                    
Sbjct: 94  AFALNIVGYPNQSLPLSILGQILKGGADKAAEAGIAIIGGH-----SITDHAPKYGLVVT 148

Query: 151 GAIPANIHWGAQTLTAGDVLLVSGTLGDH--GATILNLREQLGLDGELVSDCAVLTPLIQ 208
           G +  +     +    G+ L+++  LG       I        L G +      L     
Sbjct: 149 GFVNPSRMISKKGAKPGNALILTKPLGIGVITTGIDRKLVNNELIGRVTKQMTTLNKQAA 208

Query: 209 TLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGL---- 264
            +    GV A  D T  G+   + E   A G G  ++ + +P+ P    + +   +    
Sbjct: 209 EIMQEVGVNACTDVTGFGLLGHLREILIASGTGACITASKVPIIPETEELIQAGAVSGGT 268

Query: 265 --------------------------DALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
                                     D       G L+IAV +    ++L AL S     
Sbjct: 269 HNNYRYLRDLVEWDTRLSKEVKLILCDPQT---SGGLLIAVPQENKNKLLKALQSKEEVL 325

Query: 299 DAALIGEVVERKG 311
            A  IGEVVE  G
Sbjct: 326 TAVEIGEVVEGPG 338


>UniRef50_A8I0K0 Thiamine-monophosphate kinase n=28 Tax=Alphaproteobacteria
           RepID=A8I0K0_AZOC5
          Length = 358

 Score =  190 bits (483), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 75/328 (22%), Positives = 112/328 (34%), Gaps = 30/328 (9%)

Query: 17  QLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFF---PGGNIG 73
            +I   F     +       D A L        G  L  + D+ V    FF   P  +I 
Sbjct: 37  DIIARYFRPIATHAEARGLFDDAAL---LTPPPGCDLVLTKDALVAGVHFFADDPPASIA 93

Query: 74  KLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTK 133
           + A+    +D+A  GA P        L   +  E L A   ++   A   G  I+ GDT 
Sbjct: 94  RKALRVNLSDLAAKGARPLGALLAIALPRPMDPEWLGAFAEALGADAERFGCPILGGDTV 153

Query: 134 VVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATI---------- 183
                    + ++    GA+P            G  LLVSGT+GD    +          
Sbjct: 154 STPG----PVTLSITAFGAVPTGGFVPRTGAAPGHALLVSGTIGDAALGLQLRLAPDRPG 209

Query: 184 --LNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
                 EQ     +         PL + LRD     A  D +  G+     +  +A GCG
Sbjct: 210 FEALSAEQKAFLADRFLHPQPRLPLAEALRD--HAAAAMDVSD-GLVGDFAKMMSASGCG 266

Query: 242 IELSEAALPVKP---AVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGK 298
             +  A +P+     A       L  D L   ++ ++  AV  +A         +   G 
Sbjct: 267 GLVRAAQVPLSDAAAAAIAAEPALLADVLGGGDDYEIATAVPHDAVPVF--RAAAQAAGI 324

Query: 299 DAALIGEVVERKGVRLAGLYGVKRTLDL 326
              +IGE  +  G+ L GL G    LD 
Sbjct: 325 AVTVIGETYKGDGLDLVGLDGQPLYLDR 352


>UniRef50_B1H0F2 Thiamine-monophosphate kinase n=1 Tax=uncultured Termite group 1
           bacterium phylotype Rs-D17 RepID=B1H0F2_UNCTG
          Length = 331

 Score =  189 bits (482), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 65/328 (19%), Positives = 115/328 (35%), Gaps = 32/328 (9%)

Query: 1   MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY 60
           M NI ++   G   +  +I + F ++  N  +         D     +  + +  + D  
Sbjct: 1   MKNIDIS-SIGEFRLIDMIKNQFADSKDNKNIVAG---IGDDSFCFKSGKNNICITKDML 56

Query: 61  VIDPLF----FPGGNIGKLAICGTANDVAVSG-AIPRYLSCGFILEEGLPMETLKAVVTS 115
           V D  F         IG+ +I    +D+A  G   P Y   G  L        +K +   
Sbjct: 57  VEDVHFKKDWTNPQEIGRKSIEVNVSDIAAMGNVKPEYAFIGLGLPPKTSEIFIKNLYKG 116

Query: 116 MAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGA-IPANIHWGAQTLTAGDVLLVSG 174
             +      +AI  G+T        DK  I+   +G  I             GD++ V+ 
Sbjct: 117 FKKACDKYKMAIAGGNTVR-----ADKTIISVTIVGIGIGRERVIKRNGAGIGDLIGVTN 171

Query: 175 TLGDHGATILNLREQL------GLDGELVSDCAVLTPLI-QTLRDIPGVKALRDATRGGV 227
           T GD GA +  L +          +  L+S        + +  +    + +L DA+  G+
Sbjct: 172 TFGDAGAGVALLYKYGTKHKYNKYEHFLISKQNNPKARLKEAQKISKHLTSLTDASD-GL 230

Query: 228 NAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGL---DALNFANEGKLVIAVERNAA 284
              V   A   G G E+    +PV  +++ V          AL  A + +L+  V    A
Sbjct: 231 YISVDLLAKDSGKGAEIYMDKIPVSSSLKKVFREDKKRLDLALFGAEDYELIFTVPSLKA 290

Query: 285 EQVLAALHSHPLGKDAALIGEVVERKGV 312
           + +   +           IG++   K V
Sbjct: 291 KLLKKLVPHISY------IGKIDSSKKV 312


>UniRef50_Q73JP8 Selenide, water dikinase n=3 Tax=Bacteria RepID=SELD_TREDE
          Length = 354

 Score =  189 bits (481), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 59/343 (17%), Positives = 110/343 (32%), Gaps = 46/343 (13%)

Query: 9   GSGGQAMQQLINSLFMEAF--ANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLF 66
           G G +     ++ L        +  L    + +  D A           ST  +   P+ 
Sbjct: 20  GUGAKLSAGALDKLLKNFSVRNDDNLLVGFNTS-DDAAVYKINDKTALISTIDFFP-PVS 77

Query: 67  FPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
                 G++A   + +D+   G  P+     F + + +P + +K ++    +    AG  
Sbjct: 78  GDPYIFGQVAAANSLSDIYAMGGEPKLALNLFCITKDMPEDMIKEILRGGFDKVYEAGAI 137

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL 186
           +  G T        D      A  G +         T   GDVL+++  +G     IL  
Sbjct: 138 VCGGHT-----IYDDSPKYGLAVNGFVHPKKILENSTAKEGDVLILTKPIG---TGILLT 189

Query: 187 REQLGLDGELVSD-----CAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
             +  +      D      A L    + +     + A  D T  G+   ++E     G  
Sbjct: 190 ASKADMSPPEELDRCYKIMAFLNAKARNIMVKYKINACTDITGFGLLGHLYEMGKGSGMS 249

Query: 242 IELSEAALPVKPAVRGVCEL-------------------LGLDALNFAN-------EGKL 275
           IE+   ++P+  +V    E+                        L + +        G L
Sbjct: 250 IEVDYKSVPIYKSVIESAEMGMMPAGVYSNRNFVGDNIVFENVPLAYQDLMFDPQTSGGL 309

Query: 276 VIAVERNAAEQVLAALHSHPLGKDA---ALIGEVVERKGVRLA 315
           +I+V++  A  +   L            A+IG V +R    L 
Sbjct: 310 LISVDKEDAAALYEELSQALENTPCGKPAIIGLVTKRDEKILR 352


>UniRef50_C7BHY4 Putative uncharacterized protein n=1 Tax=Photorhabdus asymbiotica
           subsp. asymbiotica ATCC 43949 RepID=C7BHY4_PHOAA
          Length = 351

 Score =  189 bits (481), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 44/267 (16%), Positives = 87/267 (32%), Gaps = 18/267 (6%)

Query: 40  RLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFI 99
             D A ++ +G  +  + +  +   +       G  A+    +D+A  G     +   F 
Sbjct: 46  GDDTAAVLLDGQYILHACEGMLPSFVANHPYFAGWSAVMANISDIAAMGGRALSVVNSFW 105

Query: 100 LEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHW 159
                  E  + ++  M +  RA G+ +V G T +   G V +  ++ A  G        
Sbjct: 106 ---HTSSEHAQLLMQGMQDACRAYGVPLVGGHTNL---GVVYQPTLSVAIQGIARK--LL 157

Query: 160 GAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKAL 219
               +     +L++  L   G    N       +            L+  L +   V A 
Sbjct: 158 SVLHVKPQQKILIA--LNLQGKFHSNTTYWKCFERVSDHILQSQIALLPQLAEANLVHAA 215

Query: 220 RDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAV 279
           RD +  G+   +     A   G  ++  A+P    V           L        ++  
Sbjct: 216 RDISNAGILGSLLMLLEATASGAHINLDAIPKPDDVDWFK------WLQIFPSFGFLLTA 269

Query: 280 ERNAAEQVLAALHSHPLGKDAALIGEV 306
           +    ++++A    H  G    +IGE 
Sbjct: 270 DAKECDEIIALF--HRQGIACTVIGET 294


>UniRef50_D2VMQ3 Predicted protein n=1 Tax=Naegleria gruberi RepID=D2VMQ3_NAEGR
          Length = 737

 Score =  189 bits (480), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 56/349 (16%), Positives = 114/349 (32%), Gaps = 49/349 (14%)

Query: 9   GSGGQAMQQLINSLFMEAFANPWLAEQEDQ-ARLDLAQLVAEGDRLAFSTDSYVIDPLFF 67
           G G +   +L++S+  +    P         +  D A +    D +A  +      P+  
Sbjct: 391 GCGCKINSRLLDSILQKLPKQPENNSVLVGNSTCDDAAVYKINDHVAIVSTIDFFAPIVD 450

Query: 68  PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGL-PMETLKAVVTSMAETARAAGIA 126
              + G +A     +DV   G  P+             P+E L+ ++    + A  AG+A
Sbjct: 451 NPYDFGAIACANALSDVYAMGGKPQTALSVVAFPSRTLPIEILQEILRGSIDKANEAGVA 510

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLG----DHGAT 182
           IV G          ++     +  G I  +  +       GD+L ++  +G         
Sbjct: 511 IVGGH-----SIDDEEPKFGMSVNGIIHPDKIFRNVGCEEGDLLFLTKRIGTGVITSAMK 565

Query: 183 ILNLREQLGLDGELVSDCAVLTPLIQ-TLRDIPGVKALRDATRGGVNAVVHEFAAAC--- 238
           + N+  +       ++    L       LR++  V +  D T  G+   + E        
Sbjct: 566 LGNVPYESETAQSAINSMKTLNRDTSYVLREMKSVSSCTDVTGFGLLGHLKEIMKGSREI 625

Query: 239 -----GCGIELSEAALPVKPA------------------------VRGVCELLGLDALNF 269
                    +L+   +P+  +                        V     L   + L  
Sbjct: 626 CEENKDLVAQLNAKQIPLLDSSCLSLMRIVIPGGTKTNLENVQQFVEFASTLSKEEQLIL 685

Query: 270 AN---EGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLA 315
           A+    G L+  +  +  E+++ +     L  +   IGE+V++    L 
Sbjct: 686 ADAQTSGGLLFTISPDEEEKLVNSFKEKNL--NLWKIGEIVKKPNSVLI 732


>UniRef50_C6HZ14 Thiamine-monophosphate kinase n=1 Tax=Leptospirillum
           ferrodiazotrophum RepID=C6HZ14_9BACT
          Length = 335

 Score =  189 bits (480), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 71/330 (21%), Positives = 112/330 (33%), Gaps = 30/330 (9%)

Query: 16  QQLINSLFMEAFANPWLA----EQEDQARLDLAQLV-AEGDRLAFSTDSYVIDPLFF--- 67
            +LI  L     ++                D A +    G  L  +TDS      F    
Sbjct: 4   HELIAELSRILGSSSGGGAPVSGLGVGIGDDCALITQPPGCDLLVTTDSQREGVHFRWEW 63

Query: 68  -PGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIA 126
               ++G+  +    +D+   G  P +      L  G P   +  V   +AE +R  G+ 
Sbjct: 64  IDPFSVGRRLVAVNVSDIVSKGGRPAFSVVAAGLPPGDPPGRIAEVYRGIAEESRYYGVV 123

Query: 127 IVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNL 186
           +  GD      G    + +    +G IP     G   L  GD L + G  G   + +L+L
Sbjct: 124 VAGGDISRDPGG----MSLVMTLLGWIPPGTFVGRGGLAPGDCLYLVGRPGRARSGLLSL 179

Query: 187 REQLGLDGELVSDCAVLTPLI-----QTLRDIPGVKALRDATRGGVNAVVHEFAAACGCG 241
            +         +  A  TP         L   PGV ++ D T  G+   + E A A    
Sbjct: 180 EKDQDETLFSEARAAFRTPRALLREGPLLASFPGVVSMTD-TSDGLGRSLWELARASRVT 238

Query: 242 IELSEAALPVKPAVRGVCELLGLDA----LNFANEGKLVIAVERNAAEQVLAALHS---H 294
           I++ E  +PV   VR   E LG +          +  L++ V     E  L    +    
Sbjct: 239 IKVEE--IPVSKEVRKWAEALGENPGELVWTGGEDYDLLVGVSFREEEAFLKWARTDLLE 296

Query: 295 PLGKDAALIGEVVE--RKGVRLAGLYGVKR 322
              +   LIG+V E     +      G K 
Sbjct: 297 GSPEGLFLIGQVGERGDPEIIFGSGTGGKE 326


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.314    0.166    0.473 

Lambda     K      H
   0.267   0.0509    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,142,447,078
Number of Sequences: 3077464
Number of extensions: 94510432
Number of successful extensions: 320998
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 1198
Number of HSP's successfully gapped in prelim test: 705
Number of HSP's that attempted gapping in prelim test: 313466
Number of HSP's gapped (non-prelim): 2316
length of query: 336
length of database: 1,040,396,356
effective HSP length: 129
effective length of query: 207
effective length of database: 643,403,500
effective search space: 133184524500
effective search space used: 133184524500
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 94 (40.5 bits)
