BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (302 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_A1U3Y0 Sulfate adenylyltransferase subunit 2 1 n=49 Tax...   499   e-140
UniRef50_B8H5U7 Sulfate adenylyltransferase subunit 2 n=3 Tax=Al...   466   e-130
UniRef50_Q07UU1 Sulfate adenylyltransferase subunit 2 n=177 Tax=...   439   e-122
UniRef50_B8IRX8 Sulfate adenylyltransferase subunit 2 n=167 Tax=...   437   e-121
UniRef50_B9JT86 Sulfate adenylyltransferase subunit 2 n=6 Tax=Ba...   432   e-120
UniRef50_B3PTD3 Sulfate adenylyltransferase subunit 2 n=214 Tax=...   429   e-119
UniRef50_C9KJS8 Sulfate adenylyltransferase, subunit 2 n=1 Tax=M...   416   e-115
UniRef50_Q1WLL1 Sulfate adenylate transferase subunit 2 n=3 Tax=...   410   e-113
UniRef50_B3SFD5 Putative uncharacterized protein (Fragment) n=2 ...   357   3e-97
UniRef50_A1TDE9 Sulfate adenylyltransferase subunit 2 n=357 Tax=...   301   3e-80
UniRef50_B4D6P6 Sulfate adenylyltransferase n=1 Tax=Chthoniobact...   229   8e-59
UniRef50_B5E9A6 Phosphoadenosine phosphosulfate reductase n=3 Ta...   214   4e-54
UniRef50_D1J9F7 Sulfate adenylyltransferase subunit 2 n=1 Tax=un...   213   6e-54
UniRef50_Q13BZ7 Sulfate adenylyltransferase subunit 2 n=7 Tax=Br...   212   1e-53
UniRef50_Q07QS4 Sulfate adenylyltransferase subunit 2 n=35 Tax=B...   210   5e-53
UniRef50_Q24TA1 Sulfate adenylyltransferase subunit 2 n=12 Tax=B...   187   4e-46
UniRef50_A7TD47 Predicted protein n=1 Tax=Nematostella vectensis...   172   2e-41
UniRef50_B1I6V6 Phosphoadenosine phosphosulfate reductase n=1 Ta...    76   1e-12
UniRef50_C3MM97 Phosphoadenosine phosphosulfate reductase n=1 Ta...    70   7e-11
UniRef50_A1RXY7 Phosphoadenosine phosphosulfate reductase n=1 Ta...    69   1e-10
UniRef50_C6BYK7 Phosphoadenosine phosphosulfate reductase n=2 Ta...    69   2e-10
UniRef50_D2EEN4 Phosphoadenosine phosphosulfate reductase n=1 Ta...    67   9e-10
UniRef50_B6ASY4 Phosphoadenosine phosphosulfate reductase n=1 Ta...    64   5e-09
UniRef50_Q0W1C8 Putative 3\'-phosphoadenosine 5\'-phosphosulfate...    64   7e-09
UniRef50_C0GLN5 Phosphoadenosine phosphosulfate reductase n=1 Ta...    63   1e-08
UniRef50_D2R2B5 Phosphoadenosine phosphosulfate reductase n=5 Ta...    62   3e-08
UniRef50_A1SC70 Phosphoadenylylsulfate reductase (Thioredoxin) n...    60   1e-07
UniRef50_Q310R0 Phosphoadenylylsulfate reductase (Thioredoxin) n...    57   6e-07
UniRef50_Q1ITG5 Phosphoadenylylsulfate reductase (Thioredoxin) n...    57   7e-07
UniRef50_C6D4K6 Adenylylsulfate reductase, thioredoxin dependent...    55   2e-06
UniRef50_A2SQI0 Phosphoadenosine phosphosulfate reductase n=3 Ta...    55   2e-06
UniRef50_C7NUQ7 Phosphoadenosine phosphosulfate reductase n=12 T...    55   3e-06
UniRef50_D1YW88 Putative phosphoadenosine phosphosulfate reducta...    55   3e-06
UniRef50_Q72BR8 Phosphoadenosine phosphosulfate reductase, putat...    55   3e-06
UniRef50_Q9YA63 Putative uncharacterized protein n=1 Tax=Aeropyr...    55   4e-06
UniRef50_C5U5U5 Phosphoadenosine phosphosulfate reductase n=1 Ta...    55   4e-06
UniRef50_Q58383 Uncharacterized protein MJ0973 n=11 Tax=Methanoc...    53   1e-05
UniRef50_C0QUE3 Phosphoadenosine phosphosulfate reductase n=1 Ta...    52   2e-05
UniRef50_A9S2B6 Predicted protein n=3 Tax=Embryophyta RepID=A9S2...    52   2e-05
UniRef50_A2EL13 Putative uncharacterized protein n=2 Tax=Trichom...    52   3e-05
UniRef50_C1A1H0 Phosphoadenosine phosphosulfate reductase n=21 T...    52   3e-05
UniRef50_A7MSZ6 Phosphoadenosine phosphosulfate reductase n=283 ...    51   5e-05
UniRef50_Q11B66 Phosphoadenosine phosphosulfate reductase n=36 T...    50   7e-05
UniRef50_A9AB03 Phosphoadenosine phosphosulfate reductase n=7 Ta...    50   8e-05
UniRef50_C1AUL1 Phosphoadenosine phosphosulfate reductase n=11 T...    50   1e-04
UniRef50_C1SHC5 PAPS reductase/FAD synthetase family protein n=1...    50   1e-04
UniRef50_B0C9W9 Phosphoadenosine phosphosulfate reductase n=1 Ta...    49   2e-04
UniRef50_Q55309 Phosphoadenosine phosphosulfate reductase n=3 Ta...    48   4e-04
UniRef50_D0N1L8 Phosphoadenosine phosphosulfate reductase n=2 Ta...    48   5e-04
UniRef50_Q2JFN1 Phosphoadenylylsulfate reductase (Thioredoxin) n...    48   5e-04
UniRef50_D1PAG4 ATP synthase F0, A subunit n=1 Tax=Prevotella co...    48   5e-04
UniRef50_A1KL82 Phosphoadenosine phosphosulfate reductase n=31 T...    47   7e-04
UniRef50_P72794 Phosphoadenosine phosphosulfate reductase n=23 T...    47   0.001
UniRef50_C8WSE6 Adenylylsulfate reductase, thioredoxin dependent...    46   0.001
UniRef50_D0LSJ1 Phosphoadenosine phosphosulfate reductase n=1 Ta...    46   0.002
UniRef50_B8ELQ2 Phosphoadenosine phosphosulfate reductase n=8 Ta...    45   0.002
UniRef50_D1YYA8 Putative phosphoadenosine phosphosulfate reducta...    45   0.002
UniRef50_A4XB35 Phosphoadenylylsulfate reductase (Thioredoxin) n...    45   0.003
UniRef50_A6CAR6 Phosphoadenosine phosphosulfate reductase n=2 Ta...    45   0.003
UniRef50_A4WMI9 Phosphoadenosine phosphosulfate reductase n=5 Ta...    45   0.004
UniRef50_D2RH85 Phosphoadenosine phosphosulfate reductase n=1 Ta...    44   0.007
UniRef50_C5SCG2 Adenylylsulfate reductase, thioredoxin dependent...    44   0.008
UniRef50_D1CDF4 Phosphoadenosine phosphosulfate reductase n=2 Ta...    44   0.009
UniRef50_UPI000169461E phosphoadenosine phosphosulfate reductase...    43   0.012
UniRef50_A7HWV2 Phosphoadenosine phosphosulfate reductase n=1 Ta...    42   0.033
UniRef50_C9RRS4 Phosphoadenosine phosphosulfate reductase n=1 Ta...    41   0.051
UniRef50_Q4J7K3 Phosphoadenosine phosphosulfate reductase n=1 Ta...    40   0.072
UniRef50_C7IJX2 Phosphoadenosine phosphosulfate reductase n=1 Ta...    40   0.090

>UniRef50_A1U3Y0 Sulfate adenylyltransferase subunit 2 1 n=49 Tax=Bacteria
           RepID=CYSD1_MARAV
          Length = 304

 Score =  499 bits (1285), Expect = e-140,   Method: Compositional matrix adjust.
 Identities = 234/296 (79%), Positives = 262/296 (88%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           THL+QLEAESIHIIREVAAEF NPVMLYSIGKDS+VMLHLA KAF PG  PFPL+HVDT 
Sbjct: 9   THLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLAMKAFAPGKPPFPLMHVDTT 68

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           WKFREM  FRD+ A+  G +LLVH N EGV  GI PF HGSAKHTD+MKT+ LKQAL+KY
Sbjct: 69  WKFREMITFRDQMAEKLGMKLLVHTNQEGVEQGIGPFTHGSAKHTDVMKTQALKQALDKY 128

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           GFDAAFGGARRDEEKSRAKER+YSFRD+FHRWDPKNQRPELW+ YNG++NKGESIRVFPL
Sbjct: 129 GFDAAFGGARRDEEKSRAKERVYSFRDKFHRWDPKNQRPELWNLYNGKVNKGESIRVFPL 188

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
           SNWTE DIWQYI+LENIDIVPLY AAERPV+ERDG L+M+DD+R+ L+PGE    +MVRF
Sbjct: 189 SNWTELDIWQYIYLENIDIVPLYYAAERPVVERDGTLIMVDDDRMPLEPGEQPMMKMVRF 248

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           RTLGC+PLTGAVES A TLP+II+EML++TTSERQGRVID D A SME KKR+GYF
Sbjct: 249 RTLGCYPLTGAVESEAATLPDIIQEMLLTTTSERQGRVIDHDGAASMEQKKREGYF 304


>UniRef50_B8H5U7 Sulfate adenylyltransferase subunit 2 n=3 Tax=Alphaproteobacteria
           RepID=B8H5U7_CAUCN
          Length = 326

 Score =  466 bits (1200), Expect = e-130,   Method: Compositional matrix adjust.
 Identities = 221/298 (74%), Positives = 253/298 (84%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           RLTHL++LEAESIHI+REVAAE   PVMLYSIGKDS+VMLHLA KAFYP   PFPLLH+D
Sbjct: 29  RLTHLQRLEAESIHILREVAAECERPVMLYSIGKDSAVMLHLAAKAFYPSKPPFPLLHID 88

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           T WKFR+MY  RDR     G +LLVHKNP+  A GINPF HGSA HTD+ KTEGLKQAL+
Sbjct: 89  TTWKFRDMYALRDRIGSEMGFDLLVHKNPDAQARGINPFDHGSAVHTDLWKTEGLKQALS 148

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           KYGFDAAFGGARRDEEKSRAKER++SFR   HRWDPKNQRPELW+ YN + + GES+RVF
Sbjct: 149 KYGFDAAFGGARRDEEKSRAKERVFSFRSSEHRWDPKNQRPELWNLYNTRKHPGESLRVF 208

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P+SNWTE DIWQYI LENI IVPLY AAERPV+ERDG L+M+DD+R  L+ GEV + R V
Sbjct: 209 PISNWTELDIWQYIHLENIPIVPLYFAAERPVVERDGALIMVDDDRFRLRDGEVPQMRSV 268

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           RFRTLGC+PLTGAVES A TLP++I+EML++TTSERQGRVID DQ+ SME KK++GYF
Sbjct: 269 RFRTLGCYPLTGAVESTAATLPQVIQEMLLATTSERQGRVIDHDQSASMEKKKQEGYF 326


>UniRef50_Q07UU1 Sulfate adenylyltransferase subunit 2 n=177 Tax=Bacteria
           RepID=CYSD_RHOP5
          Length = 328

 Score =  439 bits (1129), Expect = e-122,   Method: Compositional matrix adjust.
 Identities = 206/296 (69%), Positives = 241/296 (81%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           +HL++LE+ESIHI+REVAAEF  PVMLYSIGKDSSV+LHLA KAF PG  PFPLLHVDT 
Sbjct: 33  SHLQRLESESIHILREVAAEFRKPVMLYSIGKDSSVLLHLAMKAFAPGKPPFPLLHVDTT 92

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           WKFREM  FRD+  +  G +LLVH NP+GVA  + PF HGSA+HTD+MKT+ L+QAL+ +
Sbjct: 93  WKFREMIAFRDQRIRELGLDLLVHVNPDGVAQRVGPFSHGSARHTDVMKTQALRQALDAH 152

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           GFDAA GGARRDEEKSRAKERI+S R   HRWDPKNQRPELW  YN  +  GES+RVFPL
Sbjct: 153 GFDAAIGGARRDEEKSRAKERIFSHRSAAHRWDPKNQRPELWSLYNTMLAPGESMRVFPL 212

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
           SNWTE DIW YI +E I IVPLY AAERPV+ERDG L+++DD R+ L+PGEV + R VRF
Sbjct: 213 SNWTELDIWDYILIERIPIVPLYFAAERPVVERDGALILVDDERMPLRPGEVPQWRSVRF 272

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           RTLGC+PLTGAV S A TLP I++EM+ S +SER+GRVIDRD   SME KK +GYF
Sbjct: 273 RTLGCYPLTGAVPSTATTLPAIVQEMMASRSSEREGRVIDRDSTASMERKKAEGYF 328


>UniRef50_B8IRX8 Sulfate adenylyltransferase subunit 2 n=167 Tax=Bacteria
           RepID=CYSD_METNO
          Length = 312

 Score =  437 bits (1123), Expect = e-121,   Method: Compositional matrix adjust.
 Identities = 211/302 (69%), Positives = 241/302 (79%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +D  RLTHL++LEAESIHI+RE  AE  NPVMLYSIGKDSSV+LHLA KAF PG LPFPL
Sbjct: 11  LDTPRLTHLQRLEAESIHIMRETVAETENPVMLYSIGKDSSVLLHLALKAFAPGRLPFPL 70

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           LHVDT WKFREM  FRD  AK  G +LLV+ NP+G+A GI P  HGS  HTD+MKT+ L+
Sbjct: 71  LHVDTTWKFREMIAFRDARAKELGLDLLVYTNPDGLARGIGPVSHGSEVHTDVMKTQALR 130

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           QAL+KY FDAAFGGARRDEE SRAKERI S R   HRWDPK QR E WH YN +  +GES
Sbjct: 131 QALDKYKFDAAFGGARRDEEASRAKERIVSLRTAQHRWDPKRQRAEPWHLYNLKKKRGES 190

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
           +RVFPLSNWTE DIW YI  E I IVPLY +AERPV+ RDG L+M+DD R+ L+PGE  +
Sbjct: 191 LRVFPLSNWTELDIWLYIEQERIPIVPLYFSAERPVVRRDGQLIMVDDERLPLEPGETPE 250

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
            R VRFRTLGC+PLTGAVES+A TLPEII E L + TSERQGRVID+D AG+ME KK++G
Sbjct: 251 LRKVRFRTLGCYPLTGAVESDAATLPEIIGETLAARTSERQGRVIDKDGAGAMERKKQEG 310

Query: 301 YF 302
           YF
Sbjct: 311 YF 312


>UniRef50_B9JT86 Sulfate adenylyltransferase subunit 2 n=6 Tax=Bacteria
           RepID=CYSD_AGRVS
          Length = 316

 Score =  432 bits (1111), Expect = e-120,   Method: Compositional matrix adjust.
 Identities = 199/295 (67%), Positives = 240/295 (81%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           HL+ LE E+IHI REVA EF NPVMLYSIGKDSSV+LHLARKAFYPG +PFPLLH+DTGW
Sbjct: 22  HLKALENEAIHIFREVAGEFDNPVMLYSIGKDSSVLLHLARKAFYPGRVPFPLLHIDTGW 81

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
           KF+EM  FRD  AK Y  +L+VH NP G   G+ PF HGSA +TDIMKTE L+QAL+   
Sbjct: 82  KFKEMIAFRDEMAKRYDLDLVVHTNPRGKTEGVTPFSHGSALYTDIMKTEALRQALDAGK 141

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           +DAAFGGARRDEE SRAKERIYSFR   H+WDP+NQRPELW+ YNG I +GES+R FPLS
Sbjct: 142 YDAAFGGARRDEEASRAKERIYSFRTPDHKWDPRNQRPELWNVYNGMIRRGESVRAFPLS 201

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           NWTE DIW+YI  ENI +VPLY A +RP +ERDGM+++ +D R++L PGE ++   +RFR
Sbjct: 202 NWTEVDIWRYIQAENIPLVPLYFAEKRPFIERDGMMILAEDERLELLPGEKVQHGSIRFR 261

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           TLGC+PLTGA+ S A+TL ++I E+ ++T SERQGR IDRDQ+GSME KKR+GYF
Sbjct: 262 TLGCFPLTGALRSEARTLDDVIAELEIATVSERQGRAIDRDQSGSMEKKKREGYF 316


>UniRef50_B3PTD3 Sulfate adenylyltransferase subunit 2 n=214 Tax=Bacteria
           RepID=CYSD_RHIE6
          Length = 317

 Score =  429 bits (1103), Expect = e-119,   Method: Compositional matrix adjust.
 Identities = 205/295 (69%), Positives = 237/295 (80%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           HL+ LE ESIHI REVAAEF  PVMLYSIGKDSSV+LHLARKAFYPG +PFPLLHV+TGW
Sbjct: 23  HLKALENESIHIFREVAAEFERPVMLYSIGKDSSVLLHLARKAFYPGRVPFPLLHVNTGW 82

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
           KFREM  FRD TAK Y  +L+ H NP G A  I PF HGSA  TDIMKTE L+QAL+   
Sbjct: 83  KFREMIAFRDETAKKYDLDLIEHINPRGAAENITPFTHGSAAFTDIMKTESLRQALDAGQ 142

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           FDAAFGGARRDEE SRAKERIYSFR   HRWDP+NQRPELW+ YNG I KGES+R FPLS
Sbjct: 143 FDAAFGGARRDEEASRAKERIYSFRTPDHRWDPRNQRPELWNVYNGMIRKGESVRAFPLS 202

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           NWTE DIW+YI  E+I +VPLY A  R  +ERDGM+++ +D R++L PGEV ++ M+RFR
Sbjct: 203 NWTEVDIWRYIQAEDIPLVPLYYAKMRKFVERDGMMILAEDPRLELLPGEVRQEGMIRFR 262

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           TLG +PLTGA+ S A TL E+I E+ ++T SERQGR IDRDQ+GSME KKR+GYF
Sbjct: 263 TLGDFPLTGAIRSQATTLQEVIAELEIATVSERQGRAIDRDQSGSMEKKKREGYF 317


>UniRef50_C9KJS8 Sulfate adenylyltransferase, subunit 2 n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KJS8_9FIRM
          Length = 302

 Score =  416 bits (1068), Expect = e-115,   Method: Compositional matrix adjust.
 Identities = 203/302 (67%), Positives = 241/302 (79%), Gaps = 6/302 (1%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           +L+HL  LEAE+I+IIREVAAE   PVMLYSIGKDS+VM+HLA KAFYP   PFP LH++
Sbjct: 3   KLSHLDALEAEAIYIIREVAAESEKPVMLYSIGKDSTVMMHLALKAFYPEKPPFPFLHIN 62

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           T WKF EM  FRD  AK YG +++ +KN EG+A G+NPF +G A +TDIMKT+ LKQAL 
Sbjct: 63  TTWKFHEMIAFRDAQAKKYGLDMIEYKNEEGLAAGVNPFDYG-ASYTDIMKTQALKQALT 121

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           KYGF AAFGG RRDEEKSRAKER++SFR+    WDPKNQRPE+W  YN QINKGESIRVF
Sbjct: 122 KYGFTAAFGGGRRDEEKSRAKERVFSFRNAAQAWDPKNQRPEMWKLYNSQINKGESIRVF 181

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI----DLQPGEVIK 240
           PLSNWTE+DIWQYI  EN++IV LY A ERPV+ERDG L+MIDD+RI    +L+P E I+
Sbjct: 182 PLSNWTEKDIWQYIRRENLEIVSLYFAKERPVIERDGNLIMIDDDRIVKKLNLKP-EDIE 240

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
            + VRFRTLGC+PLTGAVES+A TL  I+EE L +  SER  RVID + AGSME +KR+G
Sbjct: 241 HKKVRFRTLGCYPLTGAVESDADTLDAIVEETLGAVESERTSRVIDHEGAGSMERRKREG 300

Query: 301 YF 302
           YF
Sbjct: 301 YF 302


>UniRef50_Q1WLL1 Sulfate adenylate transferase subunit 2 n=3 Tax=Proteobacteria
           RepID=Q1WLL1_RHIME
          Length = 297

 Score =  410 bits (1055), Expect = e-113,   Method: Compositional matrix adjust.
 Identities = 196/293 (66%), Positives = 238/293 (81%), Gaps = 1/293 (0%)

Query: 10  RQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
           ++LEAESI I REVAA F+ PVM+YSIGKDSSV+LHLARKAFYP ++PFPLLH+DT WKF
Sbjct: 6   QRLEAESIEIFREVAASFARPVMMYSIGKDSSVLLHLARKAFYPSSIPFPLLHIDTTWKF 65

Query: 70  REMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
            +M  FR+R A+ YG EL VH N +GVA GINPF HGSA +TDIMKT+ L+QAL+  G+D
Sbjct: 66  SQMIGFRNRMAEEYGFELRVHTNADGVAQGINPFDHGSA-YTDIMKTQALRQALSSGGYD 124

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
           AA GGARRDEEKSRAK+RI+S R+  H WDPKNQRPELW  +N ++  GES+RV+PLSNW
Sbjct: 125 AAIGGARRDEEKSRAKDRIFSHRNAHHAWDPKNQRPELWRLFNTRLAPGESMRVYPLSNW 184

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
           TE DIW YI++E+I IVPLY A  RPV+ER G L+M+DD+R  L  GE   +++VRFRTL
Sbjct: 185 TELDIWTYIYVEDIPIVPLYFARPRPVVERSGTLIMVDDDRFRLDKGETPTEQVVRFRTL 244

Query: 250 GCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           GC+PLTGA+ SNA TL EII E+  S TSER+GR+ID DQAGSME KK++GYF
Sbjct: 245 GCYPLTGAIRSNAATLAEIIMEIQGSRTSEREGRLIDGDQAGSMEKKKQEGYF 297


>UniRef50_B3SFD5 Putative uncharacterized protein (Fragment) n=2 Tax=cellular
           organisms RepID=B3SFD5_TRIAD
          Length = 421

 Score =  357 bits (916), Expect = 3e-97,   Method: Compositional matrix adjust.
 Identities = 163/210 (77%), Positives = 183/210 (87%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           LTHLRQLEAESIHI REVAAEF NPVMLYS+GKDSSV+LHLARKAF PG +PFPL+HV+T
Sbjct: 212 LTHLRQLEAESIHIFREVAAEFENPVMLYSVGKDSSVLLHLARKAFAPGKIPFPLMHVNT 271

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNK 125
            WKFREM EFRD+ A+ YG EL+ + NPEG    I PF HGSAK+TDIMKT+ LKQAL+K
Sbjct: 272 TWKFREMIEFRDKMAEKYGFELISYTNPEGADNKITPFTHGSAKYTDIMKTQALKQALDK 331

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
           Y FDAAFGGARRDEEKSRAKER++SFRD+ HRWDPKNQRPELW+ YN QINKGESIRVFP
Sbjct: 332 YQFDAAFGGARRDEEKSRAKERVFSFRDKNHRWDPKNQRPELWNIYNAQINKGESIRVFP 391

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERP 215
           +SNWTE DIWQYI++ENI+I  LYLA  RP
Sbjct: 392 MSNWTELDIWQYIYMENIEIPSLYLAKPRP 421


>UniRef50_A1TDE9 Sulfate adenylyltransferase subunit 2 n=357 Tax=cellular organisms
           RepID=CYSD_MYCVP
          Length = 309

 Score =  301 bits (770), Expect = 3e-80,   Method: Compositional matrix adjust.
 Identities = 163/300 (54%), Positives = 200/300 (66%), Gaps = 9/300 (3%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           L+HLR LEAE+IHIIREVAAEF  PV+L+S GKDS VMLHLA KAF PG LPFP++HVDT
Sbjct: 16  LSHLRALEAEAIHIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMHVDT 75

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNK 125
           G  F E+   RD      G  L+V K  + +  G    V  +    + M+T  L +A+ +
Sbjct: 76  GHNFEEVLAARDELVAESGVRLVVAKVQDDIDAG---RVVETIPSRNPMQTFTLLRAIRE 132

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
             FDAAFGGARRDEEK+RAKER++SFRD F +WDPKNQRPELW+ YNG+  KGE IR FP
Sbjct: 133 NKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPELWNLYNGRHRKGEHIRAFP 192

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP--GEVIKKRM 243
           LSNWTE DIW YI  E I +  +Y A +R V ERDGML+ +  +   LQP   E I ++ 
Sbjct: 193 LSNWTEFDIWSYIGAEKIKLPSIYYAHQRKVFERDGMLLAVHKH---LQPRKDEPIIEKS 249

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQG-RVIDRDQAGSMELKKRQGYF 302
           VRFRT+G    TG VES A T+ E+I E  +S  +ER   R  DR     ME +KR+GYF
Sbjct: 250 VRFRTVGDVTCTGCVESTAATVSEVIAETAISRLTERGATRADDRISEAGMEDRKREGYF 309


>UniRef50_B4D6P6 Sulfate adenylyltransferase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D6P6_9BACT
          Length = 283

 Score =  229 bits (584), Expect = 8e-59,   Method: Compositional matrix adjust.
 Identities = 112/215 (52%), Positives = 149/215 (69%), Gaps = 1/215 (0%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           M   +L HL+ LE ESIHI+REVAAEF  P +L+S GKDS  +L LA KAF P  +P P 
Sbjct: 1   MSSYQLDHLQYLETESIHIMREVAAEFERPTILFSGGKDSICLLRLAEKAFRPSDIPMPF 60

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           L+VDTG  F E+ EFRDR A   G +L+V K  + +A GI     G     + ++   L 
Sbjct: 61  LNVDTGHHFPELNEFRDRRAAELGGKLIVRKVEDAIASGIAVPTPGEISR-NRLQIPTLL 119

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
            A++++ FD A GGARRDEEK+RAKER +SFRD F +WDP+NQRPE+W+ YN ++N GE+
Sbjct: 120 AAIDEFQFDCAIGGARRDEEKARAKERFFSFRDSFGQWDPRNQRPEIWNVYNARVNPGEN 179

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERP 215
           +RVFPLSNWTE DIW+YI  E +++  +Y + +RP
Sbjct: 180 MRVFPLSNWTEMDIWEYIKREKLEVPAIYFSHKRP 214


>UniRef50_B5E9A6 Phosphoadenosine phosphosulfate reductase n=3 Tax=Proteobacteria
           RepID=B5E9A6_GEOBB
          Length = 268

 Score =  214 bits (544), Expect = 4e-54,   Method: Compositional matrix adjust.
 Identities = 120/297 (40%), Positives = 174/297 (58%), Gaps = 31/297 (10%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           + +L+ LE++S+++IRE   +F+  + ML+S+GKDS+ +L L RKAF+ G +PFP++H+D
Sbjct: 1   MHYLQALESKSVYVIREAYQKFNGRIAMLWSVGKDSTTLLWLVRKAFF-GKIPFPVMHID 59

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           TG+KF EMYEFRDR AK +G EL+V  N E +A G+ P           +KT  LKQA++
Sbjct: 60  TGYKFPEMYEFRDRLAKEWGFELIVASNKEQLAKGMGPSSGLKLDCCTELKTNALKQAVD 119

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           +YGF +   G RRDE   RAKER +S RD   +WD +NQ  E+W  YN  + + E  R+ 
Sbjct: 120 QYGFQSILLGIRRDEHGIRAKERYFSPRDAEFQWDYENQPAEVWDQYNSFLREDEHYRIH 179

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P+ ++TE DIW+YI  E I IV LY +                        G+       
Sbjct: 180 PILHFTELDIWRYIQREQIPIVDLYRS----------------------NGGK------- 210

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGY 301
           R+R++GC P    V S A T+ E+I E+  ST SER GR  D++   +M+  +  GY
Sbjct: 211 RYRSIGCVPCCNPVPSEAATIEEMIAELETSTDSERAGRAQDKENLYTMQKLRSLGY 267


>UniRef50_D1J9F7 Sulfate adenylyltransferase subunit 2 n=1 Tax=uncultured archaeon
           RepID=D1J9F7_9ARCH
          Length = 271

 Score =  213 bits (543), Expect = 6e-54,   Method: Compositional matrix adjust.
 Identities = 120/299 (40%), Positives = 177/299 (59%), Gaps = 37/299 (12%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L++LE +SI+I+RE  AEF NP +L+S+GKDS+  L L RKAF  G +PFP++H+DTG+K
Sbjct: 3   LKELENKSIYILREAYAEFENPAILWSMGKDSTTALWLCRKAFL-GEIPFPVIHIDTGYK 61

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
           F++MYEFRDR A+ +G +L++ KN E +  G+ P   G  +    +KTE L   L+K+ F
Sbjct: 62  FKQMYEFRDRIAEEWGFDLVITKNEEAINAGMGP-KDGKLECCTKLKTEALMNYLDKHRF 120

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY--NGQINKG---ESIRV 183
           DA F   RRDE   RAKER++S RD   RW+ ++Q  E+W  Y   G+  KG      RV
Sbjct: 121 DALFLAIRRDEHGIRAKERVFSPRDEEFRWNYRDQPLEMWDQYQTQGRSEKGAVQNHTRV 180

Query: 184 FPLSNWTEQDIWQYIWLE-NIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
            P+ +W E D+W+YI  E +I + P+Y A        +G                     
Sbjct: 181 HPILHWRELDVWEYIKQEKDIPVNPMYFA-------NNGK-------------------- 213

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGY 301
             R+R+LGC P T  ++S A+T+ EI+EE+  +  +ER GR  D+++A  M+  +  GY
Sbjct: 214 --RYRSLGCEPCTSPIDSTAKTIDEIVEELRTTKVAERSGRAQDKEKAFMMQKLRALGY 270


>UniRef50_Q13BZ7 Sulfate adenylyltransferase subunit 2 n=7 Tax=Bradyrhizobiaceae
           RepID=Q13BZ7_RHOPS
          Length = 291

 Score =  212 bits (539), Expect = 1e-53,   Method: Compositional matrix adjust.
 Identities = 126/304 (41%), Positives = 170/304 (55%), Gaps = 38/304 (12%)

Query: 2   DQIR-LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +Q+R + HL  LEA+SI+I RE  A      +L+S+GKDS+VM+ LARKAF+ G +PFP 
Sbjct: 23  EQLRPMDHLDALEAQSIYIFREGFARLKKLALLWSLGKDSNVMIWLARKAFF-GRVPFPA 81

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNP--EGVAMGINPFVHGSAKHTDIMKTEG 118
           LHVDTG KF EMY FRD+ +K +  +L V   P  + V   + P    +A+     KTEG
Sbjct: 82  LHVDTGKKFPEMYAFRDQYSKEWELDLRVDPCPPIDSVDPTLPPAARSAAR-----KTEG 136

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           LK AL KYGFD    G RRDEE +RAKER++S R     WD ++Q PE W  +N     G
Sbjct: 137 LKLALAKYGFDGLIAGIRRDEEATRAKERVFSPRGTEGGWDVRDQPPEFWDQFNASPPPG 196

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +R+ P+ +WTE DIW Y   ENI I+PLYLA                      Q G+ 
Sbjct: 197 AHLRIHPILHWTEADIWAYTKRENIPIIPLYLA----------------------QNGK- 233

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKR 298
                 R+R+LG   +T  V SNA ++ EI+ E+  +   ER GR +D +   + E  + 
Sbjct: 234 ------RYRSLGDQDITFPVASNASSIDEILHELQTTKVPERAGRALDHETEDAFERLRV 287

Query: 299 QGYF 302
            GY 
Sbjct: 288 AGYL 291


>UniRef50_Q07QS4 Sulfate adenylyltransferase subunit 2 n=35 Tax=Bacteria
           RepID=Q07QS4_RHOP5
          Length = 296

 Score =  210 bits (534), Expect = 5e-53,   Method: Compositional matrix adjust.
 Identities = 121/299 (40%), Positives = 168/299 (56%), Gaps = 37/299 (12%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           + HL QLEA+SI+I+RE  A      +L+S+GKDS+VM+ LARKAF+ G +PFP +HVDT
Sbjct: 33  MDHLDQLEAQSIYILREAFARLKKLALLWSLGKDSNVMIWLARKAFF-GRVPFPAMHVDT 91

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNP--EGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           G KF EMY FRD+ +K +  +L++   P  E V   + P    +A+     KTEGLK AL
Sbjct: 92  GKKFPEMYAFRDQYSKEWDLDLILEYCPGIESVDPTLPPAARSAAR-----KTEGLKLAL 146

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
            K+GFD    G RRDEE +RAKER++S R     WD ++Q PE W  +N     G  +R+
Sbjct: 147 AKHGFDGLIAGIRRDEEATRAKERVFSPRGTEGGWDVRDQPPEFWDQFNASPPPGSHLRI 206

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            P+ +WTE DIW Y   ENI I+PLYL+                      Q G+      
Sbjct: 207 HPILHWTEADIWAYTKRENIPIIPLYLS----------------------QGGQ------ 238

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
            R+R+LG   +T  V S A  + EI++E+  +   ER GR +D +   + E  +  GY 
Sbjct: 239 -RYRSLGDADITNPVASTASNIDEILKELDETKVPERAGRALDHETEDAFERLRVAGYL 296


>UniRef50_Q24TA1 Sulfate adenylyltransferase subunit 2 n=12 Tax=Bacteria
           RepID=Q24TA1_DESHY
          Length = 293

 Score =  187 bits (475), Expect = 4e-46,   Method: Compositional matrix adjust.
 Identities = 116/323 (35%), Positives = 165/323 (51%), Gaps = 56/323 (17%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           + HL +LEA+S++I+RE   EF N  ML+SIGKDS+V+L LARKAF+ G +P PL+H+DT
Sbjct: 1   MNHLDKLEAQSVYILREAYREFKNICMLWSIGKDSTVLLWLARKAFF-GHVPIPLVHIDT 59

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDI---MKTEGLKQA 122
            +K  EM  +RD  A+ +   ++  +N E +  G   F  G          +KTE LK  
Sbjct: 60  HYKIPEMIHYRDELARQWRLTMIYGENKEALDGG-RTFPDGKTDRISCCQALKTEALKNT 118

Query: 123 L--------------------NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
           L                    N+  +     G R DEE SR+KER +S RD+ + WD  +
Sbjct: 119 LSGEWSRYILDLETGQYRPDGNREKYTGVIVGVRADEEGSRSKERYFSPRDQENDWDVGD 178

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
           Q PE W+ +      G  IR+ PL +WTE ++W+YI  E I +  LY             
Sbjct: 179 QPPEFWNQFKTDFAPGTHIRIHPLLDWTELNVWEYIQREKIPVTSLYF------------ 226

Query: 223 LMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEM---LVSTTSE 279
                    D   G+       R+R+LGC+P T  VES A+ + EIIEE+     +  +E
Sbjct: 227 ---------DQGEGK-------RYRSLGCYPCTLPVESPARNVEEIIEELRSGKFANIAE 270

Query: 280 RQGRVIDRDQAGSMELKKRQGYF 302
           R GR  D+D  G +E  +R GY 
Sbjct: 271 RSGRAQDKDDGGGLETLRRGGYM 293


>UniRef50_A7TD47 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7TD47_NEMVE
          Length = 320

 Score =  172 bits (435), Expect = 2e-41,   Method: Compositional matrix adjust.
 Identities = 88/176 (50%), Positives = 110/176 (62%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +L QLE E+I+I+RE AA+F NP +L+S GKDS V++HLA KAF PG  PFPL+H+DTG 
Sbjct: 7   YLEQLENEAIYILRETAAQFENPALLFSGGKDSIVLVHLALKAFRPGKFPFPLVHIDTGH 66

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
            F E   FRD      G +L+V    E +         G     + ++T  L  A+   G
Sbjct: 67  NFPEAIAFRDYLVNKIGEKLIVASVEESITKYNLKETPGRFPSRNALQTYALLDAIQDNG 126

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           FDA  GGARRDEEK+RAKERI+S RD F +WDPK QRPELW   NG+I   E   V
Sbjct: 127 FDACIGGARRDEEKARAKERIFSVRDDFGQWDPKLQRPELWDILNGKIKAIEKNNV 182


>UniRef50_B1I6V6 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I6V6_DESAP
          Length = 228

 Score = 76.3 bits (186), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 79/306 (25%), Positives = 118/306 (38%), Gaps = 82/306 (26%)

Query: 1   MDQIRLTH--LRQLEAESIHIIREVAAEFSNP--VMLYSIGKDSSVMLHLARKAFYPGTL 56
           MD+ RL +  L Q EAESI I RE    F        ++ GKDS V+LHL ++A   G +
Sbjct: 1   MDKERLFNWSLEQKEAESIRITRETLERFGTDRVATTFTGGKDSLVLLHLIKQAC-GGRV 59

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
           P  +L +DT   F+E+Y F DR ++ +  +L V +N E +        H    +   +K 
Sbjct: 60  PVRVLKIDTSVDFKEIYAFVDRISREWNLDLHVVRNDEALKTIKTAEDHVQCCYQ--LKA 117

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
             L   + ++  +A F   R DE+ +R  E                        Y  Q  
Sbjct: 118 VPLLNFVREHSLEAVFAAIRWDEQDARKDE-----------------------EYISQRQ 154

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
             + +R+ P+ ++ E DIW YI    +    LY         R G               
Sbjct: 155 NPDHLRMQPILHFREIDIWSYIRKYELPFCELY---------RRG--------------- 190

Query: 237 EVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELK 296
                    +R+L C P TG                     SER  R   RD+  +M+  
Sbjct: 191 ---------YRSLDCEPCTGR-----------------GGASERGAR--SRDKEAAMQRL 222

Query: 297 KRQGYF 302
           +  GYF
Sbjct: 223 REMGYF 228


>UniRef50_C3MM97 Phosphoadenosine phosphosulfate reductase n=1 Tax=Sulfolobus
           islandicus L.S.2.15 RepID=C3MM97_SULIL
          Length = 301

 Score = 70.5 bits (171), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 74/311 (23%), Positives = 119/311 (38%), Gaps = 94/311 (30%)

Query: 19  IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDR 78
           +I      F   V+++S GKDS++ L+ ARK       P   + +D    F E ++F D 
Sbjct: 56  VIEAAYNTFKRVVVVWSGGKDSTLSLYFARKVSEKLGKPLEAIIIDHYMHFDETWKFIDE 115

Query: 79  TAKAYGCELLVHKNP------------------------EGVAMGINPFVHG----SAKH 110
             K +   L+V  N                         E V    + F++     +A H
Sbjct: 116 VKKDWNVNLIVKGNERLKGHKYGDVIKISDLSEKDRKELENVGYSKDTFLYALNNIAANH 175

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
             ++KT  LK+A+ +Y  DA   G R DE  +R+ E  +S R+     +PK+        
Sbjct: 176 --LLKTVPLKEAIEEYNIDALIVGDRWDENPARSTETFFSARE-----NPKH-------- 220

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
                      RV P+  +TE+D+W +I    + I PLY    R +           D++
Sbjct: 221 ----------FRVHPILLFTERDVWNFILTNKLPIHPLYYKGFRSI-----------DDK 259

Query: 231 IDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQA 290
            + +P +          T   W                  E  +  T ER GR  D++  
Sbjct: 260 YETKPTD----------TKPAW------------------EQDLENTPERAGRAQDKENI 291

Query: 291 GSMELKKRQGY 301
             ME+ +R GY
Sbjct: 292 --MEILRRHGY 300


>UniRef50_A1RXY7 Phosphoadenosine phosphosulfate reductase n=1 Tax=Thermofilum
           pendens Hrk 5 RepID=A1RXY7_THEPD
          Length = 614

 Score = 69.3 bits (168), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 62/211 (29%), Positives = 93/211 (44%), Gaps = 36/211 (17%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           +L   EAE++  IREVA ++  PV +  S GKDS V LHLA KA   G      L  +TG
Sbjct: 210 YLLAKEAEAVSFIREVAEKYRLPVFVSLSGGKDSLVTLHLAVKAL--GNEKVKALFNNTG 267

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKH----TDIMKTEGLKQA 122
            +F E  E+  R A  YG EL+     +     + P +   A+       + K   + +A
Sbjct: 268 LEFEETVEYARRIADYYGVELIEADAGDNFWRAL-PVMGPPARDYRWCCKVTKFSTISRA 326

Query: 123 LNKYGFDAAFG--GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY--NGQINKG 178
           + K+  + A    G R+ E  +RA                    P +W NY   G +   
Sbjct: 327 VKKFFPEGALSLVGQRKYESSARALS------------------PRIWRNYWLPGVVAAS 368

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
                 P+ +W+  DIW YI++E + +  LY
Sbjct: 369 ------PVHDWSAMDIWLYIFMERLPVNKLY 393


>UniRef50_C6BYK7 Phosphoadenosine phosphosulfate reductase n=2 Tax=Desulfovibrio
           RepID=C6BYK7_DESAD
          Length = 234

 Score = 68.9 bits (167), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 53/179 (29%), Positives = 78/179 (43%), Gaps = 31/179 (17%)

Query: 37  GKDSSVMLHLARKAFYPG------TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVH 90
           GKDS+V+L L R+            L    L +DTG KF E+  FRDR A  +G ++ V 
Sbjct: 40  GKDSTVVLALWREVLKNKGKEASLVLVPQALSIDTGIKFPEVMAFRDRIALQWGVDVKVI 99

Query: 91  KNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYS 150
           + P+ V +   P      K    +K + L++A++++  D    G RRDE  SRA  R   
Sbjct: 100 R-PD-VDLSSYPIAENPVKCCADLKIKPLQKAIDEFEIDLLITGIRRDEHPSRAGRRFME 157

Query: 151 FRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
            RD                       + +   + P+  WTE DIW +I +  I    LY
Sbjct: 158 VRD-----------------------EPDHTLLNPILEWTEMDIWSFITMHQIPHCELY 193


>UniRef50_D2EEN4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Parvarchaeum acidiphilum ARMAN-4 RepID=D2EEN4_9EURY
          Length = 276

 Score = 66.6 bits (161), Expect = 9e-10,   Method: Compositional matrix adjust.
 Identities = 56/233 (24%), Positives = 97/233 (41%), Gaps = 54/233 (23%)

Query: 19  IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYP-GTLPFPLLHVDTGWKFREMYEFRD 77
           +I++    ++ P +++S GKDS+V+L L R+A    G    P L +D G  + E  +  +
Sbjct: 29  VIKDALKRYNRPTVVWSAGKDSTVVLDLVRRACKDLGMQLPPALFIDHGQHYDETMKMLE 88

Query: 78  RTAKAYGCELLVHKNPEGVA----------MGINPFVHGSAKH----------------- 110
             +K +G +++  KN + +             +N      AK                  
Sbjct: 89  DISKGWGFKMVYAKNEDVIKNVGKDNKIKLSSLNKINQDEAKRIGFNGEEFEYSLETEIG 148

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
             ++KT  +  A+ KY FDA F G R DE ++R+ E   S R                  
Sbjct: 149 NHLLKTVAMNMAIEKYRFDALFTGVRWDENEARSTEVFISPR------------------ 190

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
                   + +RV P+  + E+++W+YI+   +   PLY    R +   DG L
Sbjct: 191 -----THPDHVRVQPILPFAERNVWEYIFKYKLPTHPLYKLGYRSI---DGKL 235


>UniRef50_B6ASY4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Rhodobacterales
           bacterium HTCC2083 RepID=B6ASY4_9RHOB
          Length = 243

 Score = 64.3 bits (155), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 34/194 (17%)

Query: 10  RQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
           R LEA S   + +   +     ++   G DS+V+LHLA +   P     P+L +DTG  F
Sbjct: 15  RALEATSAIRLGQSDPQVGQIALVSGFGADSAVLLHLAAQ-LVPD---MPVLFLDTGKHF 70

Query: 70  REMYEFRDRTAKAYGCELLVHKNPEGVAMG-INPF----VHGSAKHTDIMKTEGLKQALN 124
            E  +++   A   G + L    P+  A+   +P+     H      D+ KT+ L  AL 
Sbjct: 71  NETLQYQRELASELGLQDLRTIKPDANAIAETDPYGALYSHAPDACCDLRKTQPLTLALK 130

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             GFD    G +R +  SRAK  ++                      +GQ    + +++ 
Sbjct: 131 --GFDGWITGRKRHQSVSRAKMNVFEI--------------------DGQ---SQQLKIN 165

Query: 185 PLSNWTEQDIWQYI 198
           PL++W+ QD+ QY+
Sbjct: 166 PLAHWSAQDVAQYM 179


>UniRef50_Q0W1C8 Putative 3\'-phosphoadenosine 5\'-phosphosulfate sulfotransferase
           (PAPS reductase) n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W1C8_UNCMA
          Length = 641

 Score = 63.9 bits (154), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 67/214 (31%), Positives = 92/214 (42%), Gaps = 36/214 (16%)

Query: 9   LRQLEAESIHIIREVAAEFSN-PVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           L+ +EA++I +IR VA +  N PV + +S GKDS V+ ++ARKA            VDTG
Sbjct: 222 LQSMEADAISVIRGVAGQHKNLPVTVSFSGGKDSLVVFNIARKAVN----KLKAFFVDTG 277

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN-PFVHGSAKH----TDIMKTEGLKQ 121
            +F E  EF +R A   G E+ V +   G A   N P     AK       + K   +  
Sbjct: 278 LEFPETSEFVERFAHDTGVEITVQR--AGDAFDQNFPAFGPPAKDFRWCCKVCKLGPITS 335

Query: 122 ALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
            LN         G RR E   R        R+ F                 GQI      
Sbjct: 336 LLNNSKGVITIDGKRRYESFQRGHIGTVE-RNPF---------------VPGQIG----- 374

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLY-LAAER 214
            VFP+ +W   ++W YI++E +   PLY L  ER
Sbjct: 375 -VFPVKDWRAIEVWLYIYMEKLPYNPLYDLGFER 407


>UniRef50_C0GLN5 Phosphoadenosine phosphosulfate reductase n=1
           Tax=Desulfonatronospira thiodismutans ASO3-1
           RepID=C0GLN5_9DELT
          Length = 186

 Score = 62.8 bits (151), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 62/242 (25%), Positives = 96/242 (39%), Gaps = 76/242 (31%)

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           L++DTG+KF E+ EFRD  A  +G EL V   P+  AM     +    +    +K   L+
Sbjct: 21  LNLDTGYKFPEVLEFRDEMAWEWGLELTV-AGPDSSAMQDLQEL-SKVECCRRLKVSPLQ 78

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           +A+ ++G      G RRDE  SR                P  Q          + N  + 
Sbjct: 79  EAVREHGVRVLLTGIRRDEHPSREN-------------TPDVQ----------EKNDLDY 115

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
            +V P+++WTE DIW YI L+ +    LY A                             
Sbjct: 116 YQVNPIAHWTEMDIWSYIMLKGLPYCSLYDAG---------------------------- 147

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
                +R+LGC P T                +  +  +ER GR  DR++  ++++ +  G
Sbjct: 148 -----YRSLGCKPCT----------------VKGTHMNERSGR--DREKEENLDMLRSMG 184

Query: 301 YF 302
           YF
Sbjct: 185 YF 186


>UniRef50_D2R2B5 Phosphoadenosine phosphosulfate reductase n=5 Tax=Planctomycetales
           RepID=D2R2B5_9PLAN
          Length = 273

 Score = 62.0 bits (149), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 62/247 (25%), Positives = 101/247 (40%), Gaps = 70/247 (28%)

Query: 19  IIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRD 77
           I+R   A F+    M  + G +  V+LH+  + F P T   P+ ++DTG++F E    RD
Sbjct: 66  ILRWSIARFAPKFTMATAFGPEGMVILHMLSE-FAPET---PIFNLDTGYQFPETLALRD 121

Query: 78  RTAKAYGCELLVHKNPEGV----AMGINP-FVHGSAKHTDIMKTEGLKQA-LNKYGFDAA 131
             A+ YG E+ + +    V    A    P + H   +     K E L++A L ++ + +A
Sbjct: 122 EVARRYGMEVELKRATLSVEEYEAQNGGPVYRHSPDRCCHNRKVEVLEKAVLGQHAWASA 181

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
               RRD+   RAK  I  +  +F                         ++V PL+NWT+
Sbjct: 182 I---RRDQSPDRAKAPIVGWDKKFGL-----------------------VKVSPLANWTK 215

Query: 192 QDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGC 251
           + +W +I   N+   PL+                  DN                + ++GC
Sbjct: 216 KQVWTHITEHNVPYNPLH------------------DN---------------GYTSIGC 242

Query: 252 WPLTGAV 258
           WP T AV
Sbjct: 243 WPCTRAV 249


>UniRef50_A1SC70 Phosphoadenylylsulfate reductase (Thioredoxin) n=1 Tax=Nocardioides
           sp. JS614 RepID=A1SC70_NOCSJ
          Length = 229

 Score = 59.7 bits (143), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 52/199 (26%), Positives = 85/199 (42%), Gaps = 31/199 (15%)

Query: 1   MDQIRLTHLRQLEAESI-HIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           +  +   H  +LE  S   ++R     F   +   S   D+++  HLA  +  PG     
Sbjct: 11  LQAVVFEHAEELEGVSADSVVRWARDTFGTKLCATSSMSDAAIT-HLA-SSCAPG---LD 65

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           +L +DTG+ F E   FRD+ A A+   ++  ++       I P+   S     + K   L
Sbjct: 66  VLFLDTGYHFPETLAFRDQVAAAFDVRVVDLRSKPAPGNQIPPWSTDSNDCCRLRKVVPL 125

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           +QAL   G+DA   G RR E  SR++  + S       WD  NQ                
Sbjct: 126 RQALA--GYDAWLTGIRRAESPSRSQTPVVS-------WDSHNQ---------------- 160

Query: 180 SIRVFPLSNWTEQDIWQYI 198
            ++V PL+ WT++ +  Y+
Sbjct: 161 VVKVAPLAAWTDEALAAYL 179


>UniRef50_Q310R0 Phosphoadenylylsulfate reductase (Thioredoxin) n=2
           Tax=Desulfovibrio RepID=Q310R0_DESDG
          Length = 267

 Score = 57.4 bits (137), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 71/308 (23%), Positives = 117/308 (37%), Gaps = 89/308 (28%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNP---VMLYSIGKDSSVMLHLARKAFYPGTLPFP-- 59
           R+  L Q  A +  ++  + +  + P   V+ ++ GKDS+V+L L R       +  P  
Sbjct: 39  RMIQLSQKTAYARSLLETIISNGTPPSSVVVAWTGGKDSTVVLDLWRNVLRNAGISAPPR 98

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVH-KNPEGVAMGINPFVHGSAKHTDIMKTEG 118
           +L +DTG KF E+  FRD+ A ++  +L +H   P     G  P           +K   
Sbjct: 99  VLSLDTGCKFPEVTTFRDKLAASW--QLNMHIVTPPADNTGY-PVAANVVDCCRRLKVLP 155

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAK----ERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           L+ A+          G RRDE  +RA     E++ S         P +Q           
Sbjct: 156 LQHAVESLNVSILLTGIRRDEHPARASSGHAEKVIS---------PPHQ----------- 195

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                  R+ P+ ++ E D+W Y +   +   PLY                 D+      
Sbjct: 196 -------RLHPIFDFNEMDVWAYTFERQLPYCPLY-----------------DEG----- 226

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSME 294
                      +R+LGC P T    +              ++  ERQGR   ++Q  +M+
Sbjct: 227 -----------YRSLGCKPCTSPPTN--------------TSGHERQGRNAVKEQ--NMQ 259

Query: 295 LKKRQGYF 302
             +  GYF
Sbjct: 260 TLRSLGYF 267


>UniRef50_Q1ITG5 Phosphoadenylylsulfate reductase (Thioredoxin) n=5 Tax=Bacteria
           RepID=Q1ITG5_ACIBL
          Length = 234

 Score = 57.0 bits (136), Expect = 7e-07,   Method: Compositional matrix adjust.
 Identities = 53/201 (26%), Positives = 89/201 (44%), Gaps = 32/201 (15%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLP-FPLLHVDTGWKFREM 72
           A +  +++E       P +  S   +  V+L L R+      +P  P+L +DTG+ F E+
Sbjct: 15  AAAQALVQESIEHAKRPCLTCSFQAEDVVVLDLLRQ-----VVPDIPVLFLDTGYHFAEV 69

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVAMGINPF--VHGSA--KHTDIMKTEGLKQALNKYGF 128
           Y++RD  A  +   L+     + VA   + F  ++ +A  +     K E L +AL  Y  
Sbjct: 70  YQYRDEIASKWRLNLINLLPKQSVAEQESAFGILYQTAPDRCCGARKVEPLFRALENY-- 127

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
              F G RR++ KSR+                  Q  +L+    G     E  +V PL+ 
Sbjct: 128 STWFTGLRREQSKSRSA----------------LQSIDLFTLPTGT----EIQKVSPLAE 167

Query: 189 WTEQDIWQYIWLENIDIVPLY 209
           W+ +D+W Y     I ++PLY
Sbjct: 168 WSTRDVWTYASAHGIPLLPLY 188


>UniRef50_C6D4K6 Adenylylsulfate reductase, thioredoxin dependent n=2 Tax=Bacillales
           RepID=C6D4K6_PAESJ
          Length = 231

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 52/206 (25%), Positives = 84/206 (40%), Gaps = 36/206 (17%)

Query: 11  QLEAESIHIIREVAAE-FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
           +LE  +   I   A E F N     S G +  V++ + +K   P T    + ++DT + F
Sbjct: 16  ELENATPQEILAYAVEAFPNITFACSFGAEDVVLVDMLQKV-SPKT---DIFYLDTDFHF 71

Query: 70  REMYEFRDRTAKAYGCELLVHKNP------EGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           +E YE RDR  + Y     V   P      +    G   +   +    +I K E L + L
Sbjct: 72  KETYETRDRMVERYPGIPFVEVKPLITPEEQAERHGAELWKSDANACCNIRKVEPLTRIL 131

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           +KY  DA   G RRD+  +RA  +   +  +F                         I+ 
Sbjct: 132 SKY--DAWITGIRRDQAPTRANAKKVEYDTKFGL-----------------------IKF 166

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLY 209
            P++ WT +D+W YI   ++   PL+
Sbjct: 167 NPIAGWTTEDVWNYIRENDVIYNPLH 192


>UniRef50_A2SQI0 Phosphoadenosine phosphosulfate reductase n=3
           Tax=Methanomicrobiales RepID=A2SQI0_METLZ
          Length = 472

 Score = 55.5 bits (132), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 60/221 (27%), Positives = 85/221 (38%), Gaps = 40/221 (18%)

Query: 13  EAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFR 70
           E +SI  I +V A+     P + YS GKDS V L +  KA     L  PL+  DTG +F 
Sbjct: 223 ERKSIEFIHDVIAKNPGIQPTVSYSGGKDSLVTLLITLKA----GLRLPLIFADTGLEFP 278

Query: 71  EMYEFRDRTAKAYGCELLVHKNPEGVAMGIN----PFV--HGSAKHTDIMKTEGLKQALN 124
           E  E   + ++ +   L++     G   G      P V      K   +   + L +  N
Sbjct: 279 ETIENVQKVSELFDLPLIIESGNSGFWEGFELQGPPAVDFRWCCKACKLTPVKTLIE--N 336

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           K+G   +F G R+ E   R                   Q P +W N N        I   
Sbjct: 337 KWGEAISFIGQRKFESAKRM------------------QSPRVWRNRNVPCQ----ISAA 374

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           P+ +WT    W Y++ E     PLY       L+R G  M 
Sbjct: 375 PIQHWTAMHDWLYLFREKAPYNPLYELG----LDRIGCFMC 411


>UniRef50_C7NUQ7 Phosphoadenosine phosphosulfate reductase n=12 Tax=Halobacteriaceae
           RepID=C7NUQ7_HALUD
          Length = 325

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 69/324 (21%), Positives = 134/324 (41%), Gaps = 73/324 (22%)

Query: 16  SIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAF--YPGTLPFPLLHVDTGWKFREMY 73
           +I + +    ++ NPV++++ GKDS++ L+  ++    +   +P P++ +D    F E+ 
Sbjct: 36  AIEVTKTGLEQYDNPVVMWTGGKDSTLTLYFVKEVADRFDLEVP-PVVFIDHYQHFDELI 94

Query: 74  EFRDRTAKAYGCELLVHKNPE--------GVAMGIN------------------------ 101
           +F    A+ +  E++  +N +        G+  G +                        
Sbjct: 95  DFCKHWAEEWDLEIIWARNTDVGDYVDENGLEPGDDIPVDALSEHNQHHIRNILEYEEDT 154

Query: 102 -PFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP 160
            PF+  +     ++KT  L  A+ ++  D    G R DE+++RA E  +S R        
Sbjct: 155 FPFLLDTYVGNHLLKTVALNDAIEEHDVDGILSGVRWDEQEARADETFFSPR-------- 206

Query: 161 KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
               P+++  ++         R+ P+  + E D+W+  W  N  +VP  +         +
Sbjct: 207 --HDPDIYPPHD---------RIQPILQFAEADVWEAFW--NF-VVPDTVEE----FPEE 248

Query: 221 GMLMMIDDNRIDLQPGE---VIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTT 277
           G +    ++  D    E   V  K    FR+LG    T      A   P  +++M  + T
Sbjct: 249 GYVPQGSEDLPDGLTKEDVPVSPKYFAGFRSLGSEVST----DKAAEEPAWLQDM--ANT 302

Query: 278 SERQGRVIDRDQAGSMELKKRQGY 301
           +ER GR  D++    ME  +  GY
Sbjct: 303 TERAGRAQDKEDL--MERLRDLGY 324


>UniRef50_D1YW88 Putative phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocella paludicola SANAE RepID=D1YW88_METPS
          Length = 632

 Score = 55.1 bits (131), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 58/208 (27%), Positives = 85/208 (40%), Gaps = 33/208 (15%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLP-FPLLHVDT 65
           +L  +E E+I   ++VA ++  PV + YS GKDS   L L RKA     LP F +L+++T
Sbjct: 226 YLMSIEGEAIGFAKKVAGQYRLPVTVSYSGGKDSLATLLLVRKA-----LPDFDVLYINT 280

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           G +F E  +        YG  L   K       A  + P    +     + K   +   +
Sbjct: 281 GLEFPETTQNVHDVVAQYGLRLKTAKAGSFWDAAPSLGPPSVEARWCCKVCKLGPITDLI 340

Query: 124 NKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
                D    F G RR E + RAK                +QR  +W N       G  +
Sbjct: 341 ENNYSDGCLTFIGQRRYESEVRAK----------------SQR--IWQN----PWVGNQV 378

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLY 209
              P+ +WT   IW Y++ E     PLY
Sbjct: 379 SASPIQHWTALHIWLYLFREKAPYNPLY 406


>UniRef50_Q72BR8 Phosphoadenosine phosphosulfate reductase, putative n=5
           Tax=Desulfovibrionales RepID=Q72BR8_DESVH
          Length = 255

 Score = 54.7 bits (130), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 66/272 (24%), Positives = 94/272 (34%), Gaps = 81/272 (29%)

Query: 34  YSIGKDSSVMLHLARKAF---YPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVH 90
           ++ GKDS+V L L ++     +PG +    L +DTG KF E+  FRDR A+ +  +L V 
Sbjct: 62  WTGGKDSTVALSLWQRVLDEAHPG-MRAKALSLDTGCKFPEVVAFRDRMAQEWSIDLTVV 120

Query: 91  KNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYS 150
           +   G      P           +K E L +AL +        G R DE   RA      
Sbjct: 121 RPDVGPDY---PVAVDRVACCRDLKVEPLLRALKEREIAVLLTGVRADENPERA------ 171

Query: 151 FRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYL 210
                        RP+         +    +RV P+  ++E DIW Y   + +    LY 
Sbjct: 172 ------------SRPQ-----TETFDAPSHVRVHPVLEFSEMDIWAYTMAQGLPYCTLYA 214

Query: 211 AAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIE 270
                                              +R+LGC P T               
Sbjct: 215 QG---------------------------------YRSLGCVPCTS-------------- 227

Query: 271 EMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
             LV    ER GR  D  +  SM+     GYF
Sbjct: 228 --LVVGGDERAGR--DATKEASMDALHALGYF 255


>UniRef50_Q9YA63 Putative uncharacterized protein n=1 Tax=Aeropyrum pernix
           RepID=Q9YA63_AERPE
          Length = 464

 Score = 54.7 bits (130), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 56/206 (27%), Positives = 87/206 (42%), Gaps = 25/206 (12%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           LR LE  S  ++R V  +    ++ +S GKDS+  L LA +AF  G      ++VDTG  
Sbjct: 220 LRVLEQHSAEVLRMVGEDVDTVIVPWSGGKDSTAALLLAVEAF--GRDAVKAVYVDTGID 277

Query: 69  FREMYEFRDRTAKAYGCELLVHKN--PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           F E  E+ ++ A   G +L+  +    EG+ +   P      +     K E L+QA    
Sbjct: 278 FIENAEYVEKVASTLGVDLVYARADVDEGLLIEGMPMPDPEYRWCTGRKLEALRQAFRTV 337

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
                          SR K  + +  DR    + + +RP L ++      K     V PL
Sbjct: 338 ---------------SRGKTVVVT-GDRDGESEKRGKRPPLRYD-----EKLGYPVVSPL 376

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAA 212
             W+   +  YI  + I + PLY A 
Sbjct: 377 KLWSGGHVQLYILSKGIPLNPLYEAG 402


>UniRef50_C5U5U5 Phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocaldococcus infernus ME RepID=C5U5U5_9EURY
          Length = 395

 Score = 54.7 bits (130), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 59/211 (27%), Positives = 88/211 (41%), Gaps = 43/211 (20%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
             + +LE ++ ++I+    +  N    +S GKDSSV   LA +          ++ +DTG
Sbjct: 149 NRIEKLEKKAKNLIKNYKGKEINAS--FSGGKDSSVSTLLANEIIKD----IEVIFIDTG 202

Query: 67  WKFREMYEFRDRTAKAYGCELLVHK--------NPEGVAMGINPFVHGSAKHTDIMKTEG 118
            +F E  +F    AK Y   L + K        N  GV    N + +       I K   
Sbjct: 203 LEFPETIKFVKDFAKKYDLNLTILKGGDFWEELNKRGVPTKDNRWCN------TICKLNP 256

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L++ L KY       G+RR E  SR  ER+ S+  R                  G I   
Sbjct: 257 LREYLKKYKLVYTINGSRRAESFSR--ERL-SYEKR------------------GLIE-- 293

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
             I VFP+ +W   D+W +I+L +I   PLY
Sbjct: 294 NQINVFPILDWKGVDVWSWIYLNDILYNPLY 324


>UniRef50_Q58383 Uncharacterized protein MJ0973 n=11 Tax=Methanococcales
           RepID=Y973_METJA
          Length = 411

 Score = 53.1 bits (126), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 57/217 (26%), Positives = 89/217 (41%), Gaps = 50/217 (23%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVML----YSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
            + +LE +S+ II++      N        +S GKDSSV   LA K          ++ +
Sbjct: 155 RIEKLEKKSLSIIKKYYEMCKNKNYAINTSFSGGKDSSVSTLLANKV----IDDLEVIFI 210

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNP--------EGVAMGINPFVHGSAKHTDIMK 115
           DTG +F++  +F  + AK Y   L+V K          EG+      + +       + K
Sbjct: 211 DTGLEFKDTIDFVKKFAKKYDLNLVVLKGKNFWEYLEKEGIPTKDYRWCNS------VCK 264

Query: 116 TEGLKQALNKYGFDAAFGGARRDEEKSRAK---ERIYSFRDRFHRWDPKNQRPELWHNYN 172
            E LK+ L KY       G+RR E  +R K   ER   F +                   
Sbjct: 265 LEPLKEYLKKYKRVYTIDGSRRYESFTREKLTYERKSGFIE------------------- 305

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
            QIN      +FP+ +W   D+W +I+L ++    LY
Sbjct: 306 NQIN------IFPILDWRGTDVWSWIYLNDVIYNELY 336


>UniRef50_C0QUE3 Phosphoadenosine phosphosulfate reductase n=1 Tax=Persephonella
           marina EX-H1 RepID=C0QUE3_PERMH
          Length = 235

 Score = 52.4 bits (124), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 56/229 (24%), Positives = 90/229 (39%), Gaps = 44/229 (19%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           R  H   L A+ +  ++ V   F N     S   D   ++H+  K   P  L   ++ +D
Sbjct: 10  RSDHFENLPAQDL--LKWVYQNFKNVGFTSSFSADDVSIIHMI-KEIKPDAL---IIFID 63

Query: 65  TGWKFREMYEFRDRTAKAYGCEL-----LVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           T + F E YE   +  + +   L     L+    +    G   +     K   I K E L
Sbjct: 64  TDYHFPETYELVKKIKEEWDINLKIIKPLITVEEQDRLYGEKLYEKDPDKCCQIRKVEPL 123

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           K+ L +   D    G RRD+  +RA       +   HR                 +  G+
Sbjct: 124 KRVLEE--LDVWITGMRRDQSPTRAN----IGKVETHR-----------------LPSGK 160

Query: 180 SI-RVFPLSNWTEQDIWQYIWLENIDIVPLY---------LAAERPVLE 218
           +I +V P+++WT +D+W+Y+   N+   PLY             RPVLE
Sbjct: 161 TILKVNPIADWTRKDVWKYVHENNLPYNPLYDQNYLSIGCAPCTRPVLE 209


>UniRef50_A9S2B6 Predicted protein n=3 Tax=Embryophyta RepID=A9S2B6_PHYPA
          Length = 326

 Score = 52.4 bits (124), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 46/215 (21%), Positives = 82/215 (38%), Gaps = 33/215 (15%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +Q R   L+ LEA+++  +++    F  P    ++     V+L L  +          ++
Sbjct: 84  EQARDARLQHLEAQALETLQKTVENFEKPAFPCALIAGDVVILDLLHRIGAFSDNKVKII 143

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLV-------HKNPEGVAMGINPFVHGSAKHTDIM 114
            +DT   F E Y+F     + YG +  V       +K       G + F+    ++  I 
Sbjct: 144 FIDTFHLFPETYKFLSEVEERYGFKAHVFHAADVNNKEAYDAKFGSDLFITDIEEYDRIC 203

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E   +AL     DA   G RRD    RA   ++                         
Sbjct: 204 KVEPFSRALKTLEVDAMINGRRRDHGAERAHLEVF------------------------- 238

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
             +G+ ++V PL+ W  +D W Y+   ++   PL+
Sbjct: 239 -EEGKMVKVQPLAYWEFRDCWDYLTKYSLPYHPLH 272


>UniRef50_A2EL13 Putative uncharacterized protein n=2 Tax=Trichomonas vaginalis
           RepID=A2EL13_TRIVA
          Length = 215

 Score = 52.0 bits (123), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 51/210 (24%), Positives = 89/210 (42%), Gaps = 45/210 (21%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           M  I     + L A+S+  I+E    +S+ +   Y+ GKDS V+L L             
Sbjct: 1   MSSINGLDAKILSAKSV--IKEAFERYSDKLSFCYNGGKDSVVLLDLVMNVVKENNYTIK 58

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
             +++ G +F E+ +F + + K +G +L+                    K T++   EGL
Sbjct: 59  PFYLEVGDEFDEILDFINYSEKYWGFKLM------------------RIKATNL--KEGL 98

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           ++ +N Y  ++ F G R D+  +           +   ++P N         NG     E
Sbjct: 99  EKLINTYQINSVFLGVRADDYPNI----------KMKPFEPTN---------NGW---PE 136

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
           + R+ P+ +WT  DIW+YI   N+    LY
Sbjct: 137 AERIMPILDWTYNDIWEYIDKFNLPFCSLY 166


>UniRef50_C1A1H0 Phosphoadenosine phosphosulfate reductase n=21 Tax=Actinomycetales
           RepID=CYSH_RHOE4
          Length = 247

 Score = 51.6 bits (122), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 44/172 (25%), Positives = 74/172 (43%), Gaps = 34/172 (19%)

Query: 42  VMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL-----LVHKNPEGV 96
           V++HLA +  +PG     +L +DTG+ F E    RD   + YG  +     L     + V
Sbjct: 64  VLVHLAAQ-VHPG---VDVLFLDTGYHFPETIGTRDAVEQVYGVNVINARALASVAEQDV 119

Query: 97  AMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFH 156
           A G + F     +   + K   LKQ L+  G+ A   G RR E  +RA   + SF + F 
Sbjct: 120 AEGKDLFARDPNRCCALRKVAPLKQTLS--GYSAWVTGIRRVEAPTRANAPLISFDEAFG 177

Query: 157 RWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPL 208
                                   +++ P++ W+++++  YI   +I + PL
Sbjct: 178 L-----------------------VKINPIAPWSDEEMQNYIDTNSILVNPL 206


>UniRef50_A7MSZ6 Phosphoadenosine phosphosulfate reductase n=283 Tax=Bacteria
           RepID=CYSH_VIBHB
          Length = 259

 Score = 51.2 bits (121), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 44/182 (24%), Positives = 73/182 (40%), Gaps = 36/182 (19%)

Query: 35  SIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE 94
           S G  ++VMLHL  +         P++  DTG+ F E Y+F D+        L V++  E
Sbjct: 58  SFGIQAAVMLHLVTQQ----KPDIPIILTDTGYLFAETYQFIDQLKAQLNLNLKVYRAKE 113

Query: 95  GVAMGINPF-------VHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKER 147
                   +       + G  K+  I K E +++AL +      F G RR++ +SRA   
Sbjct: 114 SANWQEARYGKLWEQGIEGIEKYNKINKVEPMRRALREQNVGTWFSGLRREQSQSRAGLP 173

Query: 148 IYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVP 207
           I S +                   NG        +  P+ +WT +D+  Y+    +   P
Sbjct: 174 ILSIQ-------------------NG------VFKFLPVIDWTNKDVHYYLEEHGLSYHP 208

Query: 208 LY 209
           L+
Sbjct: 209 LW 210


>UniRef50_Q11B66 Phosphoadenosine phosphosulfate reductase n=36
           Tax=Alphaproteobacteria RepID=CYSH_MESSB
          Length = 245

 Score = 50.4 bits (119), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 47/181 (25%), Positives = 74/181 (40%), Gaps = 36/181 (19%)

Query: 33  LYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKN 92
           + S G DS+V+LH+            P+L +DTG  F E  E+RD+ A   G   LV  +
Sbjct: 46  VSSFGADSAVLLHMVASV----DKSLPVLFLDTGQHFGETIEYRDQLASDLGLSNLVVVH 101

Query: 93  PEGVAM-----GINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKER 147
           P+   +     G +     S    +I K E + +A+  Y   A F G +R + +SRA+  
Sbjct: 102 PKSEMLSARDPGNDLHKSDSDLCCEIRKVEPMARAVEPY--SAWFTGRKRHQAESRAQMP 159

Query: 148 IYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVP 207
           ++                            G  IR+ PL+ WT  D   Y+   ++   P
Sbjct: 160 VFE-------------------------AVGPRIRINPLARWTTADQAAYMRANDLRENP 194

Query: 208 L 208
           L
Sbjct: 195 L 195


>UniRef50_A9AB03 Phosphoadenosine phosphosulfate reductase n=7 Tax=Methanococcus
           RepID=A9AB03_METM6
          Length = 512

 Score = 50.4 bits (119), Expect = 8e-05,   Method: Compositional matrix adjust.
 Identities = 53/197 (26%), Positives = 87/197 (44%), Gaps = 29/197 (14%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAF--YPGTLPFPLLHVDT 65
           ++++E+ SI  +R    +   P  + YS GKDS  +L LA +AF  +   + F +L  DT
Sbjct: 248 MQKVESNSIGFMRNTVVKIGRPASVAYSGGKDSLTVLLLALEAFKNHEDPIEFNVLFNDT 307

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           G +F E  E  ++ AK YG E+L   + E         P    +   +++ K   L   +
Sbjct: 308 GIEFNETLENIEKIAKLYGIEILKTSSGEFWEKLEEYGPPGRDNRWCSEVCKVSPLGTLI 367

Query: 124 N-KYGFDA-AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
           + KY     +F G R+ E  +R+K                  +P +W   N    K + +
Sbjct: 368 DEKYEKGCLSFVGLRKYESINRSK------------------KPRIW---NSPTIKKQML 406

Query: 182 RVFPLSNWTEQDIWQYI 198
              P+ NWT   +W YI
Sbjct: 407 SA-PILNWTAMHVWIYI 422


>UniRef50_C1AUL1 Phosphoadenosine phosphosulfate reductase n=11 Tax=Actinomycetales
           RepID=CYSH_RHOOB
          Length = 247

 Score = 50.1 bits (118), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 42  VMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV----- 96
           V++HLA +  +PG     +L +DTG+ F E    RD   + YG  ++  +    V     
Sbjct: 64  VLVHLAAQ-VHPG---VDVLFLDTGYHFAETIGTRDAVEQVYGVNVINARAEASVAEQDA 119

Query: 97  AMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFH 156
           A G + F     +   + K   LK+ L   G+ A   G RR E  +RA   + SF D F 
Sbjct: 120 AEGKDLFAREPNRCCALRKVAPLKKTL--AGYKAWVTGIRRVEAPTRANAPLISFDDAFG 177

Query: 157 RWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPL 208
                                   +++ P++ W+++D+  YI   +I + PL
Sbjct: 178 L-----------------------VKINPIAAWSDEDMQSYIDEHSILVNPL 206


>UniRef50_C1SHC5 PAPS reductase/FAD synthetase family protein n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SHC5_9BACT
          Length = 764

 Score = 49.7 bits (117), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 47/220 (21%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSI----GKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           L  +E  ++  I  V  ++ + + L+ +    GKDS+V+L L +KA   G+  F ++  D
Sbjct: 118 LDIIEQSTVKKIISVYTKYKDKLDLFHVAFSGGKDSAVLLDLVKKALPLGS--FVVVFGD 175

Query: 65  TGWKFREMYEFRDRT---AKAYGCELLVHKN------------PEGVAMGINPFVHGSAK 109
           TG +F + Y+  D+T    +A G    + K+            P   A+     VH SA 
Sbjct: 176 TGMEFPDTYDVIDKTRQMCEADGIPFYIAKSSLEPQESWVLFGPPSRALRWCCGVHKSAP 235

Query: 110 HTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWH 169
            T  +K   +    +  G   AF G R +E   RA+   Y + +       K QR +  H
Sbjct: 236 QT--LKLRAVTGKNDYTGL--AFVGVRSEESAKRAE---YDYENY-----SKKQRGQYSH 283

Query: 170 NYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
           N               +  WT  ++W Y++  NI I   Y
Sbjct: 284 N--------------SILEWTSAEVWLYLYANNIMINEAY 309


>UniRef50_B0C9W9 Phosphoadenosine phosphosulfate reductase n=1 Tax=Acaryochloris
           marina MBIC11017 RepID=B0C9W9_ACAM1
          Length = 242

 Score = 48.9 bits (115), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 34/183 (18%)

Query: 35  SIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE 94
           + G    V++ L  K   P     P+L +DT   F E  +  +     YG +L + + P+
Sbjct: 47  AFGASGMVIMDLLYKDLNPNP-SIPVLFLDTLHHFPETLKLANDAQAHYGVDLQIFR-PQ 104

Query: 95  GVAMGINPFVHGSAK--HTDI------MKTEGLKQALNKYGFDAAFGGARRDEEKSRAKE 146
           GV        H   +   TD+       K E L++ L +        G RRD+  +RAK 
Sbjct: 105 GVTSRAEFAQHYGEQLWETDLEQFHQLTKVEPLRRGLEQLQVATWITGRRRDQSSTRAKM 164

Query: 147 RIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIV 206
            I+                        + ++   ++V PL+NW+ +D+W Y+    +   
Sbjct: 165 PIF------------------------ECDRDGRLKVNPLANWSYKDVWNYLVNNQVLYN 200

Query: 207 PLY 209
           PLY
Sbjct: 201 PLY 203


>UniRef50_Q55309 Phosphoadenosine phosphosulfate reductase n=3 Tax=Bacteria
           RepID=CYSH_SYNE7
          Length = 232

 Score = 48.1 bits (113), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 40/204 (19%)

Query: 16  SIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           +  II+  A EF S  V+  S G  S+VMLHLA +         P++ +DTG+   E Y 
Sbjct: 20  ATQIIQWAATEFGSGLVLSTSFGIQSAVMLHLATQV----QPDIPVIWIDTGYLPTETYR 75

Query: 75  FRDRTAKAYGCELLVHKNPEGVA--------MGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           F     +     L V+++    A        +  +  V    ++  + K E + +AL + 
Sbjct: 76  FAAELTERLKLNLKVYQSEISPARMEALYGRLWESESVEDFNRYDQMRKVEPMNRALQEL 135

Query: 127 GFDAAFGGARRDEEKSRAKERIYSF-RDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
           G  A   G RR +   R    I    RDR+                        +IR  P
Sbjct: 136 GATAWLSGVRRQQTAHRQSMEIVELKRDRY------------------------AIR--P 169

Query: 186 LSNWTEQDIWQYIWLENIDIVPLY 209
           +  W  +D++QY+   ++   PL+
Sbjct: 170 ILGWHSRDVYQYLTAHDLPYHPLF 193


>UniRef50_D0N1L8 Phosphoadenosine phosphosulfate reductase n=2 Tax=cellular
           organisms RepID=D0N1L8_PHYIN
          Length = 382

 Score = 47.8 bits (112), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 50/209 (23%), Positives = 88/209 (42%), Gaps = 50/209 (23%)

Query: 31  VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVH 90
           V+  S G  S+VMLHL R      +   P++ VDTG+  +E Y+F     K     + V+
Sbjct: 73  VLSSSFGIQSAVMLHLTRSV----SKDIPVVWVDTGYLPKETYQFAAHLTKLLDLNVRVY 128

Query: 91  KNP------EGVAMGI----NPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEE 140
           ++P      E +   +     P  H   ++  + K E +++AL++    A   G R D+ 
Sbjct: 129 QSPITPARMEALYGKLYEIETPEAH--RQYGYMRKVEPMQRALDELNAAALLVGVRADQT 186

Query: 141 KSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWL 200
           + R                   Q  +  + Y G++      ++ P+ NW++Q+I QY+  
Sbjct: 187 QHR-------------------QHMKHVNVYEGRL------KICPILNWSKQEIEQYMTA 221

Query: 201 ENIDIVPLYLA---------AERPVLERD 220
             ++  PL            + RPV E D
Sbjct: 222 NQLEYHPLKAQGYESVGDAHSSRPVTEAD 250


>UniRef50_Q2JFN1 Phosphoadenylylsulfate reductase (Thioredoxin) n=1 Tax=Frankia sp.
           CcI3 RepID=Q2JFN1_FRASC
          Length = 223

 Score = 47.8 bits (112), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 48/201 (23%), Positives = 83/201 (41%), Gaps = 37/201 (18%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A +  I+R    EF   + + +   ++ ++  LAR          P++ +DTG+ F E  
Sbjct: 19  APAEEILRWAVGEFGTKLAIAASMAEAILVDMLARI-----RSDVPVVFIDTGYHFPETV 73

Query: 74  EFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTD------IMKTEGLKQALNKYG 127
             RD  A  Y   + +   P+   +G +         TD      + K   L +AL  Y 
Sbjct: 74  GTRDAVAGTYDLPI-ISARPQLTVVGQDAVYGQDLYRTDPDLCCRMRKVVPLDRALAPYR 132

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
             AA  G+RR E  SRAK R+         WD +  +                +++ PL+
Sbjct: 133 AWAA--GSRRAESPSRAKLRVVD-------WDARRGK----------------VKIHPLA 167

Query: 188 NWTEQDIWQYIWLENIDIVPL 208
            WT++D+ +Y+    + + PL
Sbjct: 168 AWTDEDVERYVAEHGVIVNPL 188


>UniRef50_D1PAG4 ATP synthase F0, A subunit n=1 Tax=Prevotella copri DSM 18205
           RepID=D1PAG4_9BACT
          Length = 188

 Score = 47.8 bits (112), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 42/148 (28%), Positives = 62/148 (41%), Gaps = 34/148 (22%)

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVH-KNPEGVAM-----GINPF---VHGSAKH 110
           +  +DTG  F E Y+  D+T   YG  L V   N E V       GIN F   +    + 
Sbjct: 45  IFTLDTGRLFPETYQLIDKTNMTYGINLEVFFPNYEAVQQMVKEEGINLFYNSIESRHRC 104

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
             + K E LK+A+   G D    G R+ +  +R   ++  + D               HN
Sbjct: 105 CQVRKLEPLKRAMQ--GLDVWICGLRKQQSVTRKDMQVVEWDD--------------IHN 148

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYI 198
                     I+V PL NW+E+D+ QY+
Sbjct: 149 L---------IKVNPLINWSEEDVEQYV 167


>UniRef50_A1KL82 Phosphoadenosine phosphosulfate reductase n=31 Tax=Actinomycetales
           RepID=CYSH_MYCBP
          Length = 254

 Score = 47.4 bits (111), Expect = 7e-04,   Method: Compositional matrix adjust.
 Identities = 44/173 (25%), Positives = 72/173 (41%), Gaps = 34/173 (19%)

Query: 41  SVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA--- 97
           +V++ LA K   PG    P++ +DTG+ F E    RD     Y   +L       VA   
Sbjct: 70  AVLVDLAAK-VRPG---VPVIFLDTGYHFVETIGTRDAIESVYDVRVLNVTPEHTVAEQD 125

Query: 98  --MGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRF 155
             +G + F     +   + K   L + L   G+ A   G RR +  +RA   + SF + F
Sbjct: 126 ELLGKDLFARNPHECCRLRKVVPLGKTLR--GYSAWVTGLRRVDAPTRANAPLVSFDETF 183

Query: 156 HRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPL 208
                                  + ++V PL+ WT+QD+ +YI   ++ + PL
Sbjct: 184 -----------------------KLVKVNPLAAWTDQDVQEYIADNDVLVNPL 213


>UniRef50_P72794 Phosphoadenosine phosphosulfate reductase n=23 Tax=Bacteria
           RepID=CYSH_SYNY3
          Length = 249

 Score = 46.6 bits (109), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 49/210 (23%), Positives = 88/210 (41%), Gaps = 41/210 (19%)

Query: 11  QLEAESIHIIREVAAEFSNP--VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           +LE  +   I   AA+   P  VM  S G  ++VMLHL   +  P     P++ +DTG+ 
Sbjct: 16  ELENATAQQIITWAAQTFGPGLVMSTSFGIQAAVMLHLV-TSIVPN---IPVIWIDTGYL 71

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVA--------MGINPFVHGSAKHTDIMKTEGLK 120
             E Y+F D+        L V+++P   A        +     V    ++  I K E ++
Sbjct: 72  PLETYQFADQLTGRLQLNLKVYQSPLSPARMEALYGKLWQQKDVESLNRYDQIRKVEPMQ 131

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRP-ELWHNYNGQINKGE 179
           +AL +    A   G RRD+ + R                 +N +P +L         +G 
Sbjct: 132 RALKELEAIAWLTGLRRDQTRHR-----------------QNLKPVDL---------QGN 165

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
             +V P+ +W  + +++Y+   ++   P +
Sbjct: 166 QYKVLPILDWNSKMVYEYLTAHDLPYHPFF 195


>UniRef50_C8WSE6 Adenylylsulfate reductase, thioredoxin dependent n=2
           Tax=Alicyclobacillus acidocaldarius RepID=C8WSE6_ALIAD
          Length = 234

 Score = 46.2 bits (108), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 46/203 (22%), Positives = 72/203 (35%), Gaps = 35/203 (17%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           EA    I+RE      N     S G +  V+L +         +     ++DT   F E 
Sbjct: 20  EARPEDILREALRRVPNITFACSFGAEDMVILDMLMSIDQQADV----FYLDTNVLFPET 75

Query: 73  YEFRDRTAKAYGCELLVHKNP------EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           YE  +R    YG   L    P      +    G   +         I K E L   L   
Sbjct: 76  YELIERAVAKYGIPNLHQVLPKLTLEEQAAQYGDALWSRDPNLCCKIRKVEPLAAFLA-- 133

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           G+D    G RR++  +R   +++ +  +F+                        ++V PL
Sbjct: 134 GYDGWITGIRREQAPTRRNAKVFEWDAKFN-----------------------IVKVNPL 170

Query: 187 SNWTEQDIWQYIWLENIDIVPLY 209
             WTE+D+W YI    +   PL+
Sbjct: 171 VRWTEKDVWNYIVERGVPYNPLH 193


>UniRef50_D0LSJ1 Phosphoadenosine phosphosulfate reductase n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=D0LSJ1_HALO1
          Length = 285

 Score = 45.8 bits (107), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 59/245 (24%), Positives = 93/245 (37%), Gaps = 66/245 (26%)

Query: 25  AEFSNPVMLYS-IGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAY 83
           A F+  V + +  G +   +LH+A +   P    F    +DTG+ F E  +  +R  +  
Sbjct: 64  ASFAPRVAISTAFGVEGCALLHMAVQ-IDPSVRVF---TIDTGYLFDETQQLIERMRERL 119

Query: 84  GCELLVHKNPEGVA-----MGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRD 138
           G E+        VA      G   +   S     + K E  ++AL   G DA   G RRD
Sbjct: 120 GIEIETFHPELSVAEQDERYGEALYTRDSDACCAMRKVEPTQRALR--GLDAWIAGLRRD 177

Query: 139 EE-KSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQY 197
           +   +RA+  I    +R+ R D +                   I+V PL+NW   D W+Y
Sbjct: 178 QGGATRAQLAIL---ERYQRGDAEPL-----------------IKVHPLANWNRSDTWRY 217

Query: 198 IWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGA 257
           +    +   PL                        L  G         ++++GCWP T A
Sbjct: 218 VLDNEVPYNPL------------------------LDQG---------YKSIGCWPCTRA 244

Query: 258 VESNA 262
           V ++A
Sbjct: 245 VGADA 249


>UniRef50_B8ELQ2 Phosphoadenosine phosphosulfate reductase n=8
           Tax=Alphaproteobacteria RepID=B8ELQ2_METSB
          Length = 263

 Score = 45.4 bits (106), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 43/173 (24%), Positives = 69/173 (39%), Gaps = 36/173 (20%)

Query: 31  VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVH 90
            ++ S G DS+V+LH+  +         P+L +DTG  F E   +RD+  +  G   +V 
Sbjct: 48  ALVSSFGADSAVLLHMIAEI----DRSLPVLFLDTGVLFPETLAYRDKLIERLGLTHVVT 103

Query: 91  KNP-EGVAMGINPFVHGSAKHTD----IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAK 145
             P E      +P     + H D    I K   L +AL+  GFDA   G +R +  +RA 
Sbjct: 104 LVPDEATLESEDPETFLWSSHPDRCCEIRKVIPLARALD--GFDAWISGRKRFQASTRAA 161

Query: 146 ERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYI 198
             ++   D                            ++ PL+NW+   I  Y+
Sbjct: 162 LPLFETED-------------------------NRTKINPLANWSPTQILNYL 189


>UniRef50_D1YYA8 Putative phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocella paludicola SANAE RepID=D1YYA8_METPS
          Length = 656

 Score = 45.4 bits (106), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 56/211 (26%), Positives = 91/211 (43%), Gaps = 40/211 (18%)

Query: 9   LRQLEAESIHIIREVAAEFSN---PVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           +  +E ++I++I+ V ++  N   PV + +S GKDS V+L+L +KA       F   ++D
Sbjct: 222 IEAMEKDAINVIKGVVSQGKNKELPVTVSFSGGKDSLVVLNLTKKAVKK----FEAFYID 277

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN-PFVHGSAKH----TDIMKTEGL 119
           TG +F E  +F + TAK    E+ V     G A   N P     AK       + K   +
Sbjct: 278 TGLEFPETTKFVEDTAK----EVPVKIEKAGKAFDENFPAFGPPAKDFRWCCKVCKLGPV 333

Query: 120 KQALNKYGFDA-AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
              L+++        G RR E   R               D   + P +     GQ++  
Sbjct: 334 TTHLSQFKKGVITIDGKRRYESFQRGG------------IDTVERNPFV----PGQMS-- 375

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
               VFP+ +W   ++W YI +E +    LY
Sbjct: 376 ----VFPIKDWRAIEVWLYIHMEKLPYNELY 402


>UniRef50_A4XB35 Phosphoadenylylsulfate reductase (Thioredoxin) n=3
           Tax=Actinomycetales RepID=A4XB35_SALTO
          Length = 256

 Score = 45.4 bits (106), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 49/207 (23%), Positives = 86/207 (41%), Gaps = 38/207 (18%)

Query: 10  RQLE-AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           R+LE A ++ ++R     F +   + S   D+ V++HL  +   PG     ++ +DTG  
Sbjct: 42  RELEGAPALEVVRWAVERFGDRFCVTSSMADA-VLVHLVSR-VAPGV---DVVFLDTGLH 96

Query: 69  FREMYEFRDRTAKAYGCEL------LVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
           F E    RD+ ++     +      L     +G   G   F         + K E L++A
Sbjct: 97  FPETLRVRDQVSRTMPVNVRSIRPRLTVGQQDG-EYGPRLFHRSPDDCCQLRKVESLERA 155

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           L   G+DA   G RRD+  SRA   + +F  R  +                       ++
Sbjct: 156 L--VGYDAWATGLRRDDSPSRANTPVVTFDTRRGK-----------------------VK 190

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLY 209
           V P++ WT+ D+  YI   ++ +  L+
Sbjct: 191 VNPIAAWTQADVETYISQWDVPVNELF 217


>UniRef50_A6CAR6 Phosphoadenosine phosphosulfate reductase n=2 Tax=Planctomyces
           RepID=A6CAR6_9PLAN
          Length = 263

 Score = 45.1 bits (105), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 10/101 (9%)

Query: 58  FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA------MGINPF-VHGSAKH 110
            P+L VDTG  F+E  E RDR  + YG   +V   PE         +GI    V G  + 
Sbjct: 60  IPILFVDTGVLFQETLETRDRLIQEYGVN-IVTLMPEKTMQEQTEELGILYLSVEGQEQC 118

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSF 151
            D+ KT+ L Q   +Y  DA  G  RR +   RA   I + 
Sbjct: 119 CDLRKTQPLIQVAEQY--DALIGSLRRADGGQRANVPILAI 157


>UniRef50_A4WMI9 Phosphoadenosine phosphosulfate reductase n=5 Tax=Thermoproteaceae
           RepID=A4WMI9_PYRAR
          Length = 594

 Score = 44.7 bits (104), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 53/204 (25%), Positives = 81/204 (39%), Gaps = 36/204 (17%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           H+ +   E++  I+ VA ++  PV++ YS GKDS V L L  ++     L F +   DTG
Sbjct: 208 HIERRAQEAVEFIKAVAEKYKKPVVVSYSGGKDSLVALDLTARS----GLKFYVYFNDTG 263

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMK-------TEGL 119
            +  E YE      + YG E++V    +     +  F   +  +    K       TE L
Sbjct: 264 LEPPETYENLKAVEERYGVEVIVGAAGQRFWEAMEKFGPPARDYRWCCKVIKLGPTTEAL 323

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           K    + G+ +   G R  E   RAK    S              P  W           
Sbjct: 324 KSRFPQ-GYISVV-GQRGAESFVRAKTPRVS--------------PSKW--------VAG 359

Query: 180 SIRVFPLSNWTEQDIWQYIWLENI 203
           S+   PL  WT  ++W YI+L  +
Sbjct: 360 SVVAAPLQEWTALEVWLYIFLHKL 383


>UniRef50_D2RH85 Phosphoadenosine phosphosulfate reductase n=1 Tax=Archaeoglobus
           profundus DSM 5631 RepID=D2RH85_ARCPR
          Length = 396

 Score = 43.9 bits (102), Expect = 0.007,   Method: Compositional matrix adjust.
 Identities = 50/205 (24%), Positives = 82/205 (40%), Gaps = 43/205 (20%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L  +E  SI  IRE A   + P   +S GKDS   L LA+KA   G +    +++ T ++
Sbjct: 206 LEVMERISIKFIREHANNVAVP---FSGGKDSLACLILAKKAL--GDVK--AIYIKTNYE 258

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTD----IMKTEGLKQALN 124
                E+ +R  K  G +L+V    E V   +  +  G   H +     +K E L++ + 
Sbjct: 259 MPYTEEYIERVCKRLGVDLIV----ESVKFDVEKY--GMPTHQNRWCTKLKMEALERVVK 312

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
                    G R  E + R                   +RP ++     +I        F
Sbjct: 313 SEEVKTLIVGDRDAESRVR------------------RERPVVFERIAKEI--------F 346

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLY 209
           P+  W+   +  YI +  +D+ PLY
Sbjct: 347 PIKYWSGAMVQLYILMNGLDLHPLY 371


>UniRef50_C5SCG2 Adenylylsulfate reductase, thioredoxin dependent n=3
           Tax=Proteobacteria RepID=C5SCG2_CHRVI
          Length = 256

 Score = 43.5 bits (101), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 50/208 (24%), Positives = 87/208 (41%), Gaps = 42/208 (20%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           EA +I ++ +V  E  + V   S+G +  V+  + R+      LP  +  +DTG    E 
Sbjct: 18  EAAAIELLSQVCRELDSIVFATSLGAEDMVLTEIIRRE----RLPIRIFTLDTGRLPTET 73

Query: 73  YEFRDRTAKAYGCELLVHK-NPEGVA-----MGINPF---VHGSAKHTDIMKTEGLKQAL 123
            E  +   + YG  +  +  +P+ +A      G++ F   V        + K E LK+AL
Sbjct: 74  LELIEVVERHYGTRIERYAPHPDAIADYVSRYGLDGFYDSVPARQACCRVRKLEPLKRAL 133

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG--QINKGESI 181
              G  A   G R ++  +RA+              P  +    W   NG  +IN     
Sbjct: 134 A--GQSAWVTGLRAEQSVTRAEL-------------PARE----WDAANGLEKIN----- 169

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLY 209
              PL++W+E ++W +I    +   PL+
Sbjct: 170 ---PLADWSEHEVWAFIRHHRVPYNPLH 194


>UniRef50_D1CDF4 Phosphoadenosine phosphosulfate reductase n=2 Tax=Bacteria
           RepID=D1CDF4_THET1
          Length = 248

 Score = 43.5 bits (101), Expect = 0.009,   Method: Compositional matrix adjust.
 Identities = 39/155 (25%), Positives = 65/155 (41%), Gaps = 30/155 (19%)

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKN---PEGVA--MGINPFVHGSAKHTDIM 114
           + ++DT + F E ++ ++   K YG + +  K    PE  A   G   +         I 
Sbjct: 70  VFYIDTDFLFPETHQTKEEAIKRYGIKPIAFKTKLTPEAQAEKYGDELWKRNPDLCCHIR 129

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E  ++AL   G  A   G RRD+  +R                 +N RP  W    G 
Sbjct: 130 KVEPTREALK--GRSAWITGLRRDQSSTR-----------------RNVRPVEWDYKFGL 170

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
                  ++ PL+ W E+++W+YI+  N+   PL+
Sbjct: 171 Y------KINPLAYWNEREVWRYIFKHNVPYNPLH 199


>UniRef50_UPI000169461E phosphoadenosine phosphosulfate reductase n=1 Tax=Paenibacillus
           larvae subsp. larvae BRL-230010 RepID=UPI000169461E
          Length = 179

 Score = 43.1 bits (100), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 30/144 (20%)

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKH-----TDIM 114
           + ++DT   F+E Y  +DR  + Y  E +  +    +A   + F     K       +I 
Sbjct: 8   IFYLDTHVHFKETYLTKDRLQEKYNIEFIQVEPKISLAEQADRFGEELWKSDPNSCCNIR 67

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E L + L++Y  DA   G RRD+  +RA     ++  +F                   
Sbjct: 68  KVEPLSRILSEY--DAWITGIRRDQAPTRANAPKAAYDTKF------------------- 106

Query: 175 INKGESIRVFPLSNWTEQDIWQYI 198
               +  +  PL+NWT  D+W YI
Sbjct: 107 ----DLAKFNPLANWTSDDVWDYI 126


>UniRef50_A7HWV2 Phosphoadenosine phosphosulfate reductase n=1 Tax=Parvibaculum
           lavamentivorans DS-1 RepID=A7HWV2_PARL1
          Length = 252

 Score = 41.6 bits (96), Expect = 0.033,   Method: Compositional matrix adjust.
 Identities = 47/187 (25%), Positives = 78/187 (41%), Gaps = 35/187 (18%)

Query: 23  VAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAK 81
           +  EF   + ++ S G +S+V+LH+  +   P T   P++ ++TG  F E   FRDR  +
Sbjct: 31  IKTEFPGKIAVVSSFGAESAVLLHMVAQ-VDPTT---PVIFLNTGKLFGETLRFRDRLQE 86

Query: 82  AYGC----------ELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAA 131
             G             L  K+P G     +P          + K   L++AL   GFDA+
Sbjct: 87  KLGLTDIRAVGPHPADLAAKDPNGGLWNADP-----DACCYVRKVLPLERAL--AGFDAS 139

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
             G +R +  +RA              DP  +         G  + G   ++ PLS W +
Sbjct: 140 ITGRKRFQTNARAG------------MDPIEEEKIRGTGVPGS-DAGTRFKINPLSYWGQ 186

Query: 192 QDIWQYI 198
            D+ +Y+
Sbjct: 187 DDLERYM 193


>UniRef50_C9RRS4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Fibrobacter
           succinogenes subsp. succinogenes S85 RepID=C9RRS4_FIBSS
          Length = 579

 Score = 40.8 bits (94), Expect = 0.051,   Method: Compositional matrix adjust.
 Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 47/219 (21%)

Query: 9   LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV--D 64
           L  L +E+   I++ AA +   N V+ +S GKDSSV   +  KA    +L    +H+  +
Sbjct: 158 LNALISEAHAFIKKEAANYPEENIVLSFSGGKDSSVTADIVTKALGNPSL----VHIFGN 213

Query: 65  TGWKFREMYEFRDRTAK-----AYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           T  +F +  E+  R  K      +   +   +N   V   I P          + KT  +
Sbjct: 214 TTLEFPQTVEYAKRFKKNHPFAIFETSINEDQNFMDVCEDIGPPARIMRWCCSMFKTGPI 273

Query: 120 KQALNKYGFDA---AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
            + LN    +     F G RR E  SR+K                         YN   +
Sbjct: 274 TRVLNSLYRNQQILTFYGIRRAESASRSK-------------------------YNRVES 308

Query: 177 KGESIRV------FPLSNWTEQDIWQYIWLENIDIVPLY 209
             ES+++       P+ +W + DIW Y+  EN+D    Y
Sbjct: 309 GKESVKIQKQTVASPIIDWKDIDIWLYLLAENVDFNDAY 347


>UniRef50_Q4J7K3 Phosphoadenosine phosphosulfate reductase n=1 Tax=Sulfolobus
           acidocaldarius RepID=Q4J7K3_SULAC
          Length = 211

 Score = 40.4 bits (93), Expect = 0.072,   Method: Compositional matrix adjust.
 Identities = 43/180 (23%), Positives = 67/180 (37%), Gaps = 49/180 (27%)

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNP----------------------EGVAMGI 100
           +D    F E +EF +R  K +G  ++V  N                       E   +G 
Sbjct: 10  IDHFMHFDETWEFIERVKKEWGVSVVVKGNERLKGHKYGDVVKVSELSREDREELQRLGY 69

Query: 101 N----PFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFH 156
           N     F   +     ++KT  LK+A+     DA   G R DE  +RA E  +S R+   
Sbjct: 70  NREEFVFALNNIAGNHLLKTVPLKEAVKDLKIDALIVGVRWDENPARASETFFSPRE--- 126

Query: 157 RWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
             DP +                   RV  +  +TE+DIW++     + + PLY    R +
Sbjct: 127 --DPPH------------------TRVHTILLFTERDIWEFTLGNRLPVHPLYYKGYRSL 166


>UniRef50_C7IJX2 Phosphoadenosine phosphosulfate reductase n=1 Tax=Clostridium
           papyrosolvens DSM 2782 RepID=C7IJX2_9CLOT
          Length = 276

 Score = 40.0 bits (92), Expect = 0.090,   Method: Compositional matrix adjust.
 Identities = 49/217 (22%), Positives = 79/217 (36%), Gaps = 37/217 (17%)

Query: 2   DQIRLTHL-RQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLP--- 57
           D   L+HL RQL+   +HI      E+   +   +  K+ + M  L  K +     P   
Sbjct: 80  DSTVLSHLVRQLQPNILHIFSNTTCEYPETLQHINWEKEHNGMNILIVKPYDKYKKPWNF 139

Query: 58  --------FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAK 109
                   FP+   D     R     +    +    + +  +    ++      ++ S K
Sbjct: 140 KRVVKEDGFPMYSKDVANAIRTYRRAKSDKTRQNSIDYITRRFKRFLSY---KDLNISDK 196

Query: 110 HTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWH 169
             + +K   +KQA  K G   A  G   +E +                     QR   W 
Sbjct: 197 CCEKLKKTPIKQAARKLGMQCAILGILAEESR---------------------QRELDWM 235

Query: 170 NYNGQI-NKGESIRVFPLSNWTEQDIWQYIWLENIDI 205
           NY   + N  +  +  PLS WTE DI++YI L N+ I
Sbjct: 236 NYGCNVFNVKKDNQCKPLSFWTENDIYEYIELYNLKI 272


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A1U3Y0 Sulfate adenylyltransferase subunit 2 1 n=49 Tax...   433   e-120
UniRef50_B8H5U7 Sulfate adenylyltransferase subunit 2 n=3 Tax=Al...   421   e-116
UniRef50_B9JT86 Sulfate adenylyltransferase subunit 2 n=6 Tax=Ba...   409   e-113
UniRef50_Q07UU1 Sulfate adenylyltransferase subunit 2 n=177 Tax=...   408   e-112
UniRef50_B8IRX8 Sulfate adenylyltransferase subunit 2 n=167 Tax=...   408   e-112
UniRef50_B3PTD3 Sulfate adenylyltransferase subunit 2 n=214 Tax=...   396   e-109
UniRef50_Q1WLL1 Sulfate adenylate transferase subunit 2 n=3 Tax=...   390   e-107
UniRef50_C9KJS8 Sulfate adenylyltransferase, subunit 2 n=1 Tax=M...   381   e-104
UniRef50_A1TDE9 Sulfate adenylyltransferase subunit 2 n=357 Tax=...   340   4e-92
UniRef50_B5E9A6 Phosphoadenosine phosphosulfate reductase n=3 Ta...   335   9e-91
UniRef50_D1J9F7 Sulfate adenylyltransferase subunit 2 n=1 Tax=un...   321   2e-86
UniRef50_Q07QS4 Sulfate adenylyltransferase subunit 2 n=35 Tax=B...   313   5e-84
UniRef50_B3SFD5 Putative uncharacterized protein (Fragment) n=2 ...   311   2e-83
UniRef50_Q13BZ7 Sulfate adenylyltransferase subunit 2 n=7 Tax=Br...   305   1e-81
UniRef50_Q24TA1 Sulfate adenylyltransferase subunit 2 n=12 Tax=B...   302   1e-80
UniRef50_B4D6P6 Sulfate adenylyltransferase n=1 Tax=Chthoniobact...   261   2e-68
UniRef50_A7TD47 Predicted protein n=1 Tax=Nematostella vectensis...   216   6e-55
UniRef50_Q310R0 Phosphoadenylylsulfate reductase (Thioredoxin) n...   207   4e-52
UniRef50_B1I6V6 Phosphoadenosine phosphosulfate reductase n=1 Ta...   201   2e-50
UniRef50_C6BYK7 Phosphoadenosine phosphosulfate reductase n=2 Ta...   195   1e-48
UniRef50_C3MM97 Phosphoadenosine phosphosulfate reductase n=1 Ta...   193   6e-48
UniRef50_Q72BR8 Phosphoadenosine phosphosulfate reductase, putat...   190   4e-47
UniRef50_C7NUQ7 Phosphoadenosine phosphosulfate reductase n=12 T...   188   2e-46
UniRef50_D2EEN4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   183   5e-45
UniRef50_C0QUE3 Phosphoadenosine phosphosulfate reductase n=1 Ta...   183   7e-45
UniRef50_A9S2B6 Predicted protein n=3 Tax=Embryophyta RepID=A9S2...   176   1e-42
UniRef50_Q1ITG5 Phosphoadenylylsulfate reductase (Thioredoxin) n...   175   2e-42
UniRef50_C0GLN5 Phosphoadenosine phosphosulfate reductase n=1 Ta...   174   4e-42
UniRef50_Q0W1C8 Putative 3\'-phosphoadenosine 5\'-phosphosulfate...   173   5e-42
UniRef50_D1YW88 Putative phosphoadenosine phosphosulfate reducta...   169   7e-41
UniRef50_A1RXY7 Phosphoadenosine phosphosulfate reductase n=1 Ta...   168   2e-40
UniRef50_D2R2B5 Phosphoadenosine phosphosulfate reductase n=5 Ta...   167   4e-40
UniRef50_A1SC70 Phosphoadenylylsulfate reductase (Thioredoxin) n...   167   6e-40
UniRef50_C6D4K6 Adenylylsulfate reductase, thioredoxin dependent...   166   1e-39
UniRef50_C8WSE6 Adenylylsulfate reductase, thioredoxin dependent...   164   2e-39
UniRef50_A2SQI0 Phosphoadenosine phosphosulfate reductase n=3 Ta...   164   3e-39
UniRef50_A9AB03 Phosphoadenosine phosphosulfate reductase n=7 Ta...   162   1e-38
UniRef50_B6ASY4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   161   3e-38
UniRef50_Q9YA63 Putative uncharacterized protein n=1 Tax=Aeropyr...   159   1e-37
UniRef50_Q58383 Uncharacterized protein MJ0973 n=11 Tax=Methanoc...   158   2e-37
UniRef50_Q55309 Phosphoadenosine phosphosulfate reductase n=3 Ta...   157   6e-37
UniRef50_Q2JFN1 Phosphoadenylylsulfate reductase (Thioredoxin) n...   156   7e-37
UniRef50_P72794 Phosphoadenosine phosphosulfate reductase n=23 T...   156   9e-37
UniRef50_C5U5U5 Phosphoadenosine phosphosulfate reductase n=1 Ta...   155   2e-36
UniRef50_Q11B66 Phosphoadenosine phosphosulfate reductase n=36 T...   154   3e-36
UniRef50_C1A1H0 Phosphoadenosine phosphosulfate reductase n=21 T...   154   3e-36
UniRef50_C1AUL1 Phosphoadenosine phosphosulfate reductase n=11 T...   152   1e-35
UniRef50_B0C9W9 Phosphoadenosine phosphosulfate reductase n=1 Ta...   151   3e-35
UniRef50_D0LSJ1 Phosphoadenosine phosphosulfate reductase n=1 Ta...   151   3e-35
UniRef50_A7MSZ6 Phosphoadenosine phosphosulfate reductase n=283 ...   149   1e-34
UniRef50_D0N1L8 Phosphoadenosine phosphosulfate reductase n=2 Ta...   149   2e-34
UniRef50_A2EL13 Putative uncharacterized protein n=2 Tax=Trichom...   144   4e-33
UniRef50_A1KL82 Phosphoadenosine phosphosulfate reductase n=31 T...   142   2e-32
UniRef50_C1SHC5 PAPS reductase/FAD synthetase family protein n=1...   133   6e-30
UniRef50_D1PAG4 ATP synthase F0, A subunit n=1 Tax=Prevotella co...   118   2e-25

Sequences not found previously or not previously below threshold:

UniRef50_Q0W3A3 Putative 3\'-phosphoadenosine 5\'-phosphosulfate...   165   2e-39
UniRef50_D1CDF4 Phosphoadenosine phosphosulfate reductase n=2 Ta...   151   4e-35
UniRef50_A4XB35 Phosphoadenylylsulfate reductase (Thioredoxin) n...   150   5e-35
UniRef50_D1YYA8 Putative phosphoadenosine phosphosulfate reducta...   149   1e-34
UniRef50_Q5HKZ5 Phosphoadenosine phosphosulfate reductase n=110 ...   148   2e-34
UniRef50_Q60377 Uncharacterized protein MJ0066 n=5 Tax=Methanoca...   146   1e-33
UniRef50_Q12UR6 Phosphoadenosine phosphosulfate reductase fused ...   145   1e-33
UniRef50_P56860 Phosphoadenosine phosphosulfate reductase n=4 Ta...   145   2e-33
UniRef50_B9XLS6 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   142   1e-32
UniRef50_D2L597 Phosphoadenosine phosphosulfate reductase n=1 Ta...   142   2e-32
UniRef50_A7NG75 Phosphoadenosine phosphosulfate reductase n=2 Ta...   141   3e-32
UniRef50_A4WMI9 Phosphoadenosine phosphosulfate reductase n=5 Ta...   141   4e-32
UniRef50_Q2S5G4 Phosphoadenosine phosphosulfate reductase n=2 Ta...   141   4e-32
UniRef50_C5QND2 Phosphoadenosine phosphosulfate reductase n=5 Ta...   141   4e-32
UniRef50_Q7NK24 Phosphoadenosine phosphosulfate reductase n=6 Ta...   139   9e-32
UniRef50_B8ELQ2 Phosphoadenosine phosphosulfate reductase n=8 Ta...   139   9e-32
UniRef50_C5A452 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   139   1e-31
UniRef50_Q1GFS4 Phosphoadenylylsulfate reductase (Thioredoxin) n...   137   3e-31
UniRef50_Q164V6 Phosophoadenylyl-sulfate reductase n=24 Tax=Rhod...   137   5e-31
UniRef50_B1VHQ3 Adenosine phosphosulfate reductase n=17 Tax=Cory...   136   9e-31
UniRef50_Q8DK35 Phosphoadenosine phosphosulfate reductase n=9 Ta...   136   1e-30
UniRef50_B0T3S8 Phosphoadenosine phosphosulfate reductase n=7 Ta...   136   1e-30
UniRef50_B5IFS1 Phosphoadenosine phosphosulfate reductase n=2 Ta...   136   1e-30
UniRef50_Q2FND9 Phosphoadenosine phosphosulfate reductase n=7 Ta...   136   1e-30
UniRef50_Q12WD1 Phosphoadenosine phosphosulfate reductase n=1 Ta...   133   5e-30
UniRef50_A7HWV2 Phosphoadenosine phosphosulfate reductase n=1 Ta...   133   5e-30
UniRef50_C4XSH1 Putative adenylyltransferase n=1 Tax=Desulfovibr...   133   6e-30
UniRef50_Q4J7K3 Phosphoadenosine phosphosulfate reductase n=1 Ta...   133   7e-30
UniRef50_C6P7J4 Adenylylsulfate reductase, thioredoxin dependent...   133   7e-30
UniRef50_C1XVG3 Phosphoadenylylsulfate reductase (Thioredoxin) n...   132   1e-29
UniRef50_A2BKK3 Phosphoadenosine 5'-phosphosulfate reductase n=1...   131   2e-29
UniRef50_UPI000169461E phosphoadenosine phosphosulfate reductase...   131   4e-29
UniRef50_A8AAE7 Phosphoadenosine phosphosulfate reductase n=1 Ta...   130   5e-29
UniRef50_Q2FU39 Uncharacterized domain 2 n=2 Tax=Methanomicrobia...   130   7e-29
UniRef50_D1I5Z9 Whole genome shotgun sequence of line PN40024, s...   129   1e-28
UniRef50_A1VQ08 Phosphoadenylylsulfate reductase (Thioredoxin) n...   129   2e-28
UniRef50_A3DN95 Phosphoadenosine phosphosulfate reductase n=2 Ta...   128   2e-28
UniRef50_A2BN02 Phosphoadenosine phosphosulfate reductase n=1 Ta...   127   5e-28
UniRef50_A9KBQ9 Phosphoadenosine phosphosulfate reductase n=3 Ta...   127   6e-28
UniRef50_B4WAM0 Phosophoadenylyl-sulfate reductase subfamily, pu...   127   6e-28
UniRef50_Q2Y9X1 Phosphoadenylylsulfate reductase (Thioredoxin) n...   126   8e-28
UniRef50_A3TKH9 Phosphoadenosine phosphosulfate reductase n=3 Ta...   126   1e-27
UniRef50_Q1AXE9 Phosphoadenylylsulfate reductase (Thioredoxin) n...   125   2e-27
UniRef50_A2C6A4 Phosphoadenosine phosphosulfate reductase n=27 T...   125   2e-27
UniRef50_Q467V4 Phosphoadenosine phosphosulfate reductase n=3 Ta...   125   2e-27
UniRef50_Q2G577 Phosphoadenylylsulfate reductase (Thioredoxin) n...   124   3e-27
UniRef50_B5Y5U1 Predicted protein (Fragment) n=1 Tax=Phaeodactyl...   124   3e-27
UniRef50_C4LKR1 Adenosine phosphosulfate reductase n=5 Tax=Actin...   124   3e-27
UniRef50_A4YFD1 Phosphoadenylylsulfate reductase (Thioredoxin) n...   124   5e-27
UniRef50_C5SCG2 Adenylylsulfate reductase, thioredoxin dependent...   124   5e-27
UniRef50_Q01NE3 Adenylylsulfate kinase / phosphoadenylylsulfate ...   123   8e-27
UniRef50_B8CCL3 Phosphoadenosine-phosphosulphate reductase n=1 T...   122   2e-26
UniRef50_A1SNA9 Phosphoadenylylsulfate reductase (Thioredoxin) n...   122   2e-26
UniRef50_B2GI28 Adenosine 5'-phosphosulfate reductase n=24 Tax=A...   122   2e-26
UniRef50_P92979 5'-adenylylsulfate reductase 1, chloroplastic n=...   121   3e-26
UniRef50_D2RH85 Phosphoadenosine phosphosulfate reductase n=1 Ta...   119   1e-25
UniRef50_A6WVB8 Phosphoadenosine phosphosulfate reductase n=2 Ta...   119   1e-25
UniRef50_Q2W561 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   119   1e-25
UniRef50_A5W608 Phosphoadenylylsulfate reductase (Thioredoxin) n...   119   2e-25
UniRef50_UPI000038E1FC phosphoadenosine phosphosulfate reductase...   119   2e-25
UniRef50_Q11WI2 Phosphoadenylylsulfate reductase (Thioredoxin) n...   119   2e-25
UniRef50_C9RRS4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   117   4e-25
UniRef50_C6WVG4 Adenylylsulfate reductase, thioredoxin dependent...   117   5e-25
UniRef50_B5IDE7 Phosphoadenosine phosphosulfate reductase family...   117   6e-25
UniRef50_A3DLJ9 Phosphoadenosine phosphosulfate reductase n=1 Ta...   117   6e-25
UniRef50_A5PAV0 Phosphoadenosine phosphosulfate reductase n=1 Ta...   117   6e-25
UniRef50_Q0BUS4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   117   7e-25
UniRef50_Q7M9C9 APS REDUCTASE n=1 Tax=Wolinella succinogenes Rep...   116   1e-24
UniRef50_Q5KLW1 Phosphoadenylyl-sulfate reductase (Thioredoxin),...   116   1e-24
UniRef50_B7R5I5 Iron-sulfur protein n=1 Tax=Thermococcus sp. AM4...   115   2e-24
UniRef50_A3UHA4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   115   2e-24
UniRef50_Q3YAU0 5'-adenylylsulfate reductase n=2 Tax=Viridiplant...   115   2e-24
UniRef50_Q3B2L6 Phosphoadenylylsulfate reductase (Thioredoxin) n...   114   3e-24
UniRef50_Q3A3P4 Phosphoadenylylsulfate reductase (Thioredoxin) n...   114   4e-24
UniRef50_P56859 Phosphoadenosine phosphosulfate reductase n=12 T...   114   4e-24
UniRef50_A3UEI0 Phosphoadenosine phosphosulfate reductase n=1 Ta...   113   6e-24
UniRef50_C7JH54 Phosphoadenosine phosphosulfate reductase n=8 Ta...   113   7e-24
UniRef50_B1L7P4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   113   7e-24
UniRef50_C9KJN4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   113   9e-24
UniRef50_C5TAI7 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   113   1e-23
UniRef50_B7UDE0 Adenosine phosphosulfate reductase n=1 Tax=Coryn...   112   2e-23
UniRef50_Q30U94 Phosphoadenylylsulfate reductase (Thioredoxin) n...   112   2e-23
UniRef50_Q0EZE5 Phosphoadenosine phosphosulfate reductase n=1 Ta...   111   2e-23
UniRef50_B8FTN0 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   111   3e-23
UniRef50_Q39RP8 Phosphoadenylylsulfate reductase (Thioredoxin) n...   111   3e-23
UniRef50_Q8UH67 Phosphoadenosine phosphosulfate reductase n=10 T...   111   4e-23
UniRef50_A1WQX9 Phosphoadenylylsulfate reductase (Thioredoxin) n...   111   4e-23
UniRef50_Q8TXP0 Predicted RNA modification enzyme consisting of ...   111   5e-23
UniRef50_Q0ASV0 Phosphoadenylylsulfate reductase (Thioredoxin) n...   110   5e-23
UniRef50_B8GIL3 Aminotransferase class V n=2 Tax=Archaea RepID=B...   110   8e-23
UniRef50_A8AC84 Phosphoadenosine phosphosulfate reductase n=1 Ta...   109   9e-23
UniRef50_Q1Q0N4 Similar to phosphoadenosine phosphosulfate reduc...   109   1e-22
UniRef50_Q9JRT1 Phosphoadenosine phosphosulfate reductase n=103 ...   109   2e-22
UniRef50_A6GTB0 Phosphoadenosine phosphosulfate reductase n=3 Ta...   108   2e-22
UniRef50_Q3SNX7 Phosphoadenylylsulfate reductase (Thioredoxin) n...   108   3e-22
UniRef50_A9A540 Adenylylsulfate reductase, thioredoxin dependent...   108   3e-22
UniRef50_A6CAR6 Phosphoadenosine phosphosulfate reductase n=2 Ta...   107   3e-22
UniRef50_C6QHX4 Adenylylsulfate reductase, thioredoxin dependent...   107   4e-22
UniRef50_A5E7W2 Phosphoadenosine phosphosulfate reductase n=3 Ta...   107   4e-22
UniRef50_P18408 Phosphoadenosine phosphosulfate reductase n=50 T...   107   5e-22
UniRef50_Q758M0 AEL259Wp n=1 Tax=Eremothecium gossypii RepID=Q75...   107   6e-22
UniRef50_B3T667 Putative phosphoadenosine phosphosulfate reducta...   106   9e-22
UniRef50_A2BJV9 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   106   9e-22
UniRef50_Q2RT16 Phosphoadenylylsulfate reductase (Thioredoxin) n...   106   1e-21
UniRef50_Q8RG73 Phosphoadenosine phosphosulfate reductase n=3 Ta...   106   1e-21
UniRef50_C3KS73 Phosphoadenosine phosphosulfate reductase family...   104   3e-21
UniRef50_C7G6A6 Phosphoadenosine phosphosulfate reductase n=3 Ta...   102   2e-20
UniRef50_C5ETD1 Phosphoadenosine phosphosulfate reductase n=4 Ta...   102   2e-20
UniRef50_A9USG3 Predicted protein (Fragment) n=1 Tax=Monosiga br...   102   2e-20
UniRef50_A3DMN4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   102   2e-20
UniRef50_B1I2U8 Phosphoadenosine phosphosulfate reductase n=1 Ta...   101   2e-20
UniRef50_C6Y361 Phosphoadenosine phosphosulfate reductase n=2 Ta...   101   4e-20
UniRef50_A0Z1B4 Possible 3'-phosphoadenosine 5'-phosphosulfate s...   101   4e-20
UniRef50_B8D5B9 Phosphoadenosine phosphosulfate reductase n=1 Ta...   100   1e-19
UniRef50_D0JAV6 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...    99   1e-19
UniRef50_Q0RVM7 Probable phosphoadenylyl-sulfate reductase (Thio...    99   1e-19
UniRef50_C6E124 Phosphoadenosine phosphosulfate reductase n=1 Ta...    99   2e-19
UniRef50_B5Y6E1 Phosphoadenosine phosphosulfate reductase family...    99   2e-19
UniRef50_A6EMB0 Phosphoadenosine phosphosulfate reductase n=1 Ta...    98   3e-19
UniRef50_Q0RWS5 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...    97   6e-19
UniRef50_A5INH9 Phosphoadenosine phosphosulfate reductase n=2 Ta...    97   6e-19
UniRef50_B4D6P5 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...    97   7e-19
UniRef50_B8KW50 Phosphoadenosine phosphosulfate reductase n=1 Ta...    97   7e-19
UniRef50_Q97JS3 Similar to phospho-adenylylsulfate sulfotransfer...    97   9e-19
UniRef50_Q0VNW4 Phosphoadenosine phosphosulfate reductase n=5 Ta...    95   3e-18
UniRef50_A8A8R5 Phosphoadenosine phosphosulfate reductase n=1 Ta...    95   3e-18
UniRef50_D1HPZ6 Whole genome shotgun sequence of line PN40024, s...    94   5e-18
UniRef50_D0J215 Phosphoadenosine phosphosulfate reductase n=9 Ta...    94   5e-18
UniRef50_A1UQ75 Phosphoadenosine phosphosulfate reductase n=3 Ta...    94   6e-18
UniRef50_UPI0001C3554A hypothetical protein ChatD1_24037 n=1 Tax...    94   6e-18
UniRef50_D0J9F7 Phosphoadenosine phosphosulphate reductase n=1 T...    94   6e-18
UniRef50_B8GLW1 Phosphoadenosine phosphosulfate reductase n=1 Ta...    94   7e-18
UniRef50_Q8IR76 CG4407, isoform B n=8 Tax=Drosophila RepID=Q8IR7...    93   9e-18
UniRef50_Q04PC4 Phosphoadenylyl-sulfate reductase n=10 Tax=Bacte...    93   1e-17
UniRef50_O33579 Phosphoadenosine phosphosulfate reductase (Fragm...    93   1e-17
UniRef50_Q9VYI5 CG4407, isoform A n=4 Tax=melanogaster subgroup ...    93   2e-17
UniRef50_C0SDH1 Phosphoadenosine phosphosulfate reductase n=1 Ta...    92   2e-17
UniRef50_Q74M42 NEQ525 n=1 Tax=Nanoarchaeum equitans RepID=Q74M4...    92   2e-17
UniRef50_UPI0001C36A5F hypothetical protein ChatD1_04226 n=1 Tax...    91   5e-17
UniRef50_A6DI54 Possible 3'-phosphoadenosine 5'-phosphosulfate s...    91   5e-17
UniRef50_B5YMF1 Predicted protein (Fragment) n=1 Tax=Thalassiosi...    91   6e-17
UniRef50_C5K7J4 FAD synthetase, putative n=1 Tax=Perkinsus marin...    91   6e-17
UniRef50_B1ZSB4 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...    90   8e-17
UniRef50_Q1VVA9 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...    90   8e-17
UniRef50_Q4FSU0 Phosphoadenylylsulfate reductase (Thioredoxin) n...    90   9e-17
UniRef50_Q8GA37 Z1203 protein n=70 Tax=Bacteria RepID=Q8GA37_ECOLX     90   1e-16
UniRef50_A9FNW8 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...    89   2e-16
UniRef50_B6YXY8 3'-phosphoadenosine 5'-phosphosulfate reductase ...    88   3e-16
UniRef50_A2DE77 Phosphoadenosine phosphosulfate reductase family...    87   6e-16
UniRef50_B1YE28 Phosphoadenosine phosphosulfate reductase n=1 Ta...    87   7e-16
UniRef50_D0TA45 Putative uncharacterized protein n=1 Tax=Bactero...    87   9e-16
UniRef50_A3XKN2 Possible 3'-phosphoadenosine 5'-phosphosulfate s...    86   1e-15
UniRef50_A3RYW5 Co-activator of prophage gene expression IbrA n=...    86   1e-15
UniRef50_A6Q5M8 Phosphoadenosine phosphosulfate reductase n=1 Ta...    86   2e-15
UniRef50_A0DD33 Chromosome undetermined scaffold_46, whole genom...    86   2e-15
UniRef50_UPI000186D96A molybdopterin- binding protein, putative ...    85   2e-15
UniRef50_B3RLV6 Putative uncharacterized protein (Fragment) n=1 ...    85   2e-15
UniRef50_A0YCE4 Possible 3'-phosphoadenosine 5'-phosphosulfate s...    85   2e-15
UniRef50_C0EBX2 Putative uncharacterized protein n=2 Tax=Clostri...    85   3e-15
UniRef50_A6L476 Putative sulfate adenylate transferase, subunit ...    84   8e-15
UniRef50_Q4JBE9 Conserved Archaeal protein n=1 Tax=Sulfolobus ac...    83   8e-15
UniRef50_B0D4U7 Predicted protein n=2 Tax=Agaricales RepID=B0D4U...    83   9e-15
UniRef50_C4WUE8 ACYPI004304 protein n=2 Tax=Acyrthosiphon pisum ...    83   1e-14
UniRef50_D1IAI6 Whole genome shotgun sequence of line PN40024, s...    83   1e-14
UniRef50_Q8MZ99 AT21573p n=9 Tax=Drosophila RepID=Q8MZ99_DROME         83   1e-14
UniRef50_A8IWB7 FAD synthetase n=1 Tax=Chlamydomonas reinhardtii...    81   4e-14
UniRef50_Q4DC85 Phosphoadenosine phosphosulfate reductase-like p...    81   4e-14
UniRef50_B7J801 Conserved domain protein n=1 Tax=Acidithiobacill...    81   6e-14
UniRef50_Q22017 FAD synthetase region n=3 Tax=Caenorhabditis Rep...    81   7e-14
UniRef50_C7TXS2 RFad1, flavin adenine dinucleotide synthetase, h...    81   7e-14
UniRef50_Q16R18 Molybdopterin-binding n=3 Tax=Culicidae RepID=Q1...    80   7e-14
UniRef50_UPI0000DB7DE3 PREDICTED: similar to CG4407-PA, isoform ...    79   2e-13
UniRef50_A1ZIJ8 Phosphoadenosine phosphosulfate reductase n=2 Ta...    79   2e-13
UniRef50_A7RYI4 Predicted protein n=1 Tax=Nematostella vectensis...    78   5e-13
UniRef50_B9IAG2 Predicted protein (Fragment) n=1 Tax=Populus tri...    77   7e-13
UniRef50_UPI0001C369AF putative aminotransferase, class V n=1 Ta...    77   1e-12
UniRef50_C7IJX2 Phosphoadenosine phosphosulfate reductase n=1 Ta...    76   1e-12
UniRef50_C7IDU2 Phosphoadenosine phosphosulfate reductase n=1 Ta...    76   2e-12
UniRef50_UPI00005251CA PREDICTED: similar to FAD1 flavin adenine...    76   2e-12
UniRef50_Q8NFF5 FAD synthetase region n=38 Tax=Chordata RepID=FA...    76   2e-12
UniRef50_Q8TYP8 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...    75   3e-12
UniRef50_P77216 Uncharacterized protein ybdN n=243 Tax=Bacteria ...    75   3e-12
UniRef50_A8NQH7 Probable molybdopterin binding domain containing...    75   3e-12
UniRef50_C4L4E5 Sulfurtransferase DndC n=3 Tax=Bacillales RepID=...    75   3e-12
UniRef50_UPI0001BC4F2A hypothetical protein FuD12_09796 n=1 Tax=...    74   4e-12
UniRef50_C4PZB7 Molybdopterin-binding, putative n=1 Tax=Schistos...    74   4e-12
UniRef50_UPI0000D574FF PREDICTED: similar to RFad1, flavin adeni...    74   5e-12
UniRef50_B7FZY6 Predicted protein (Fragment) n=2 Tax=Bacillariop...    74   6e-12
UniRef50_UPI0001C364B3 hypothetical protein ChatD1_04731 n=1 Tax...    74   7e-12
UniRef50_A8UF11 Phosphoadenosine phosphosulfate reductase n=1 Ta...    74   8e-12
UniRef50_D0MWH8 FAD synthetase, putative n=1 Tax=Phytophthora in...    73   1e-11
UniRef50_Q6IWS1 Gp61 n=1 Tax=Burkholderia phage BcepB1A RepID=Q6...    73   1e-11
UniRef50_C0RZY2 FAD synthetase n=3 Tax=Paracoccidioides brasilie...    73   2e-11
UniRef50_UPI0000E49112 PREDICTED: similar to MGC82686 protein n=...    73   2e-11
UniRef50_C4G023 Putative uncharacterized protein n=1 Tax=Abiotro...    73   2e-11

>UniRef50_A1U3Y0 Sulfate adenylyltransferase subunit 2 1 n=49 Tax=Bacteria
           RepID=CYSD1_MARAV
          Length = 304

 Score =  433 bits (1113), Expect = e-120,   Method: Composition-based stats.
 Identities = 234/302 (77%), Positives = 264/302 (87%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +   + THL+QLEAESIHIIREVAAEF NPVMLYSIGKDS+VMLHLA KAF PG  PFPL
Sbjct: 3   LTPPKKTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLAMKAFAPGKPPFPL 62

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           +HVDT WKFREM  FRD+ A+  G +LLVH N EGV  GI PF HGSAKHTD+MKT+ LK
Sbjct: 63  MHVDTTWKFREMITFRDQMAEKLGMKLLVHTNQEGVEQGIGPFTHGSAKHTDVMKTQALK 122

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           QAL+KYGFDAAFGGARRDEEKSRAKER+YSFRD+FHRWDPKNQRPELW+ YNG++NKGES
Sbjct: 123 QALDKYGFDAAFGGARRDEEKSRAKERVYSFRDKFHRWDPKNQRPELWNLYNGKVNKGES 182

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
           IRVFPLSNWTE DIWQYI+LENIDIVPLY AAERPV+ERDG L+M+DD+R+ L+PGE   
Sbjct: 183 IRVFPLSNWTELDIWQYIYLENIDIVPLYYAAERPVVERDGTLIMVDDDRMPLEPGEQPM 242

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
            +MVRFRTLGC+PLTGAVES A TLP+II+EML++TTSERQGRVID D A SME KKR+G
Sbjct: 243 MKMVRFRTLGCYPLTGAVESEAATLPDIIQEMLLTTTSERQGRVIDHDGAASMEQKKREG 302

Query: 301 YF 302
           YF
Sbjct: 303 YF 304


>UniRef50_B8H5U7 Sulfate adenylyltransferase subunit 2 n=3 Tax=Alphaproteobacteria
           RepID=B8H5U7_CAUCN
          Length = 326

 Score =  421 bits (1083), Expect = e-116,   Method: Composition-based stats.
 Identities = 221/299 (73%), Positives = 253/299 (84%)

Query: 4   IRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
            RLTHL++LEAESIHI+REVAAE   PVMLYSIGKDS+VMLHLA KAFYP   PFPLLH+
Sbjct: 28  ARLTHLQRLEAESIHILREVAAECERPVMLYSIGKDSAVMLHLAAKAFYPSKPPFPLLHI 87

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           DT WKFR+MY  RDR     G +LLVHKNP+  A GINPF HGSA HTD+ KTEGLKQAL
Sbjct: 88  DTTWKFRDMYALRDRIGSEMGFDLLVHKNPDAQARGINPFDHGSAVHTDLWKTEGLKQAL 147

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           +KYGFDAAFGGARRDEEKSRAKER++SFR   HRWDPKNQRPELW+ YN + + GES+RV
Sbjct: 148 SKYGFDAAFGGARRDEEKSRAKERVFSFRSSEHRWDPKNQRPELWNLYNTRKHPGESLRV 207

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
           FP+SNWTE DIWQYI LENI IVPLY AAERPV+ERDG L+M+DD+R  L+ GEV + R 
Sbjct: 208 FPISNWTELDIWQYIHLENIPIVPLYFAAERPVVERDGALIMVDDDRFRLRDGEVPQMRS 267

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           VRFRTLGC+PLTGAVES A TLP++I+EML++TTSERQGRVID DQ+ SME KK++GYF
Sbjct: 268 VRFRTLGCYPLTGAVESTAATLPQVIQEMLLATTSERQGRVIDHDQSASMEKKKQEGYF 326


>UniRef50_B9JT86 Sulfate adenylyltransferase subunit 2 n=6 Tax=Bacteria
           RepID=CYSD_AGRVS
          Length = 316

 Score =  409 bits (1051), Expect = e-113,   Method: Composition-based stats.
 Identities = 199/295 (67%), Positives = 240/295 (81%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           HL+ LE E+IHI REVA EF NPVMLYSIGKDSSV+LHLARKAFYPG +PFPLLH+DTGW
Sbjct: 22  HLKALENEAIHIFREVAGEFDNPVMLYSIGKDSSVLLHLARKAFYPGRVPFPLLHIDTGW 81

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
           KF+EM  FRD  AK Y  +L+VH NP G   G+ PF HGSA +TDIMKTE L+QAL+   
Sbjct: 82  KFKEMIAFRDEMAKRYDLDLVVHTNPRGKTEGVTPFSHGSALYTDIMKTEALRQALDAGK 141

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           +DAAFGGARRDEE SRAKERIYSFR   H+WDP+NQRPELW+ YNG I +GES+R FPLS
Sbjct: 142 YDAAFGGARRDEEASRAKERIYSFRTPDHKWDPRNQRPELWNVYNGMIRRGESVRAFPLS 201

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           NWTE DIW+YI  ENI +VPLY A +RP +ERDGM+++ +D R++L PGE ++   +RFR
Sbjct: 202 NWTEVDIWRYIQAENIPLVPLYFAEKRPFIERDGMMILAEDERLELLPGEKVQHGSIRFR 261

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           TLGC+PLTGA+ S A+TL ++I E+ ++T SERQGR IDRDQ+GSME KKR+GYF
Sbjct: 262 TLGCFPLTGALRSEARTLDDVIAELEIATVSERQGRAIDRDQSGSMEKKKREGYF 316


>UniRef50_Q07UU1 Sulfate adenylyltransferase subunit 2 n=177 Tax=Bacteria
           RepID=CYSD_RHOP5
          Length = 328

 Score =  408 bits (1048), Expect = e-112,   Method: Composition-based stats.
 Identities = 206/296 (69%), Positives = 241/296 (81%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           +HL++LE+ESIHI+REVAAEF  PVMLYSIGKDSSV+LHLA KAF PG  PFPLLHVDT 
Sbjct: 33  SHLQRLESESIHILREVAAEFRKPVMLYSIGKDSSVLLHLAMKAFAPGKPPFPLLHVDTT 92

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           WKFREM  FRD+  +  G +LLVH NP+GVA  + PF HGSA+HTD+MKT+ L+QAL+ +
Sbjct: 93  WKFREMIAFRDQRIRELGLDLLVHVNPDGVAQRVGPFSHGSARHTDVMKTQALRQALDAH 152

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           GFDAA GGARRDEEKSRAKERI+S R   HRWDPKNQRPELW  YN  +  GES+RVFPL
Sbjct: 153 GFDAAIGGARRDEEKSRAKERIFSHRSAAHRWDPKNQRPELWSLYNTMLAPGESMRVFPL 212

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
           SNWTE DIW YI +E I IVPLY AAERPV+ERDG L+++DD R+ L+PGEV + R VRF
Sbjct: 213 SNWTELDIWDYILIERIPIVPLYFAAERPVVERDGALILVDDERMPLRPGEVPQWRSVRF 272

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           RTLGC+PLTGAV S A TLP I++EM+ S +SER+GRVIDRD   SME KK +GYF
Sbjct: 273 RTLGCYPLTGAVPSTATTLPAIVQEMMASRSSEREGRVIDRDSTASMERKKAEGYF 328


>UniRef50_B8IRX8 Sulfate adenylyltransferase subunit 2 n=167 Tax=Bacteria
           RepID=CYSD_METNO
          Length = 312

 Score =  408 bits (1047), Expect = e-112,   Method: Composition-based stats.
 Identities = 211/302 (69%), Positives = 241/302 (79%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +D  RLTHL++LEAESIHI+RE  AE  NPVMLYSIGKDSSV+LHLA KAF PG LPFPL
Sbjct: 11  LDTPRLTHLQRLEAESIHIMRETVAETENPVMLYSIGKDSSVLLHLALKAFAPGRLPFPL 70

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           LHVDT WKFREM  FRD  AK  G +LLV+ NP+G+A GI P  HGS  HTD+MKT+ L+
Sbjct: 71  LHVDTTWKFREMIAFRDARAKELGLDLLVYTNPDGLARGIGPVSHGSEVHTDVMKTQALR 130

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           QAL+KY FDAAFGGARRDEE SRAKERI S R   HRWDPK QR E WH YN +  +GES
Sbjct: 131 QALDKYKFDAAFGGARRDEEASRAKERIVSLRTAQHRWDPKRQRAEPWHLYNLKKKRGES 190

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
           +RVFPLSNWTE DIW YI  E I IVPLY +AERPV+ RDG L+M+DD R+ L+PGE  +
Sbjct: 191 LRVFPLSNWTELDIWLYIEQERIPIVPLYFSAERPVVRRDGQLIMVDDERLPLEPGETPE 250

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
            R VRFRTLGC+PLTGAVES+A TLPEII E L + TSERQGRVID+D AG+ME KK++G
Sbjct: 251 LRKVRFRTLGCYPLTGAVESDAATLPEIIGETLAARTSERQGRVIDKDGAGAMERKKQEG 310

Query: 301 YF 302
           YF
Sbjct: 311 YF 312


>UniRef50_B3PTD3 Sulfate adenylyltransferase subunit 2 n=214 Tax=Bacteria
           RepID=CYSD_RHIE6
          Length = 317

 Score =  396 bits (1016), Expect = e-109,   Method: Composition-based stats.
 Identities = 205/295 (69%), Positives = 237/295 (80%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           HL+ LE ESIHI REVAAEF  PVMLYSIGKDSSV+LHLARKAFYPG +PFPLLHV+TGW
Sbjct: 23  HLKALENESIHIFREVAAEFERPVMLYSIGKDSSVLLHLARKAFYPGRVPFPLLHVNTGW 82

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
           KFREM  FRD TAK Y  +L+ H NP G A  I PF HGSA  TDIMKTE L+QAL+   
Sbjct: 83  KFREMIAFRDETAKKYDLDLIEHINPRGAAENITPFTHGSAAFTDIMKTESLRQALDAGQ 142

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           FDAAFGGARRDEE SRAKERIYSFR   HRWDP+NQRPELW+ YNG I KGES+R FPLS
Sbjct: 143 FDAAFGGARRDEEASRAKERIYSFRTPDHRWDPRNQRPELWNVYNGMIRKGESVRAFPLS 202

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           NWTE DIW+YI  E+I +VPLY A  R  +ERDGM+++ +D R++L PGEV ++ M+RFR
Sbjct: 203 NWTEVDIWRYIQAEDIPLVPLYYAKMRKFVERDGMMILAEDPRLELLPGEVRQEGMIRFR 262

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           TLG +PLTGA+ S A TL E+I E+ ++T SERQGR IDRDQ+GSME KKR+GYF
Sbjct: 263 TLGDFPLTGAIRSQATTLQEVIAELEIATVSERQGRAIDRDQSGSMEKKKREGYF 317


>UniRef50_Q1WLL1 Sulfate adenylate transferase subunit 2 n=3 Tax=Proteobacteria
           RepID=Q1WLL1_RHIME
          Length = 297

 Score =  390 bits (1002), Expect = e-107,   Method: Composition-based stats.
 Identities = 196/293 (66%), Positives = 238/293 (81%), Gaps = 1/293 (0%)

Query: 10  RQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
           ++LEAESI I REVAA F+ PVM+YSIGKDSSV+LHLARKAFYP ++PFPLLH+DT WKF
Sbjct: 6   QRLEAESIEIFREVAASFARPVMMYSIGKDSSVLLHLARKAFYPSSIPFPLLHIDTTWKF 65

Query: 70  REMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
            +M  FR+R A+ YG EL VH N +GVA GINPF HGSA +TDIMKT+ L+QAL+  G+D
Sbjct: 66  SQMIGFRNRMAEEYGFELRVHTNADGVAQGINPFDHGSA-YTDIMKTQALRQALSSGGYD 124

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
           AA GGARRDEEKSRAK+RI+S R+  H WDPKNQRPELW  +N ++  GES+RV+PLSNW
Sbjct: 125 AAIGGARRDEEKSRAKDRIFSHRNAHHAWDPKNQRPELWRLFNTRLAPGESMRVYPLSNW 184

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
           TE DIW YI++E+I IVPLY A  RPV+ER G L+M+DD+R  L  GE   +++VRFRTL
Sbjct: 185 TELDIWTYIYVEDIPIVPLYFARPRPVVERSGTLIMVDDDRFRLDKGETPTEQVVRFRTL 244

Query: 250 GCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           GC+PLTGA+ SNA TL EII E+  S TSER+GR+ID DQAGSME KK++GYF
Sbjct: 245 GCYPLTGAIRSNAATLAEIIMEIQGSRTSEREGRLIDGDQAGSMEKKKQEGYF 297


>UniRef50_C9KJS8 Sulfate adenylyltransferase, subunit 2 n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KJS8_9FIRM
          Length = 302

 Score =  381 bits (978), Expect = e-104,   Method: Composition-based stats.
 Identities = 201/301 (66%), Positives = 238/301 (79%), Gaps = 4/301 (1%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           +L+HL  LEAE+I+IIREVAAE   PVMLYSIGKDS+VM+HLA KAFYP   PFP LH++
Sbjct: 3   KLSHLDALEAEAIYIIREVAAESEKPVMLYSIGKDSTVMMHLALKAFYPEKPPFPFLHIN 62

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           T WKF EM  FRD  AK YG +++ +KN EG+A G+NPF +G A +TDIMKT+ LKQAL 
Sbjct: 63  TTWKFHEMIAFRDAQAKKYGLDMIEYKNEEGLAAGVNPFDYG-ASYTDIMKTQALKQALT 121

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           KYGF AAFGG RRDEEKSRAKER++SFR+    WDPKNQRPE+W  YN QINKGESIRVF
Sbjct: 122 KYGFTAAFGGGRRDEEKSRAKERVFSFRNAAQAWDPKNQRPEMWKLYNSQINKGESIRVF 181

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ---PGEVIKK 241
           PLSNWTE+DIWQYI  EN++IV LY A ERPV+ERDG L+MIDD+RI  +     E I+ 
Sbjct: 182 PLSNWTEKDIWQYIRRENLEIVSLYFAKERPVIERDGNLIMIDDDRIVKKLNLKPEDIEH 241

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGY 301
           + VRFRTLGC+PLTGAVES+A TL  I+EE L +  SER  RVID + AGSME +KR+GY
Sbjct: 242 KKVRFRTLGCYPLTGAVESDADTLDAIVEETLGAVESERTSRVIDHEGAGSMERRKREGY 301

Query: 302 F 302
           F
Sbjct: 302 F 302


>UniRef50_A1TDE9 Sulfate adenylyltransferase subunit 2 n=357 Tax=cellular organisms
           RepID=CYSD_MYCVP
          Length = 309

 Score =  340 bits (871), Expect = 4e-92,   Method: Composition-based stats.
 Identities = 160/301 (53%), Positives = 199/301 (66%), Gaps = 5/301 (1%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           +  L+HLR LEAE+IHIIREVAAEF  PV+L+S GKDS VMLHLA KAF PG LPFP++H
Sbjct: 13  RYELSHLRALEAEAIHIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMH 72

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
           VDTG  F E+   RD      G  L+V K  + +  G    V  +    + M+T  L +A
Sbjct: 73  VDTGHNFEEVLAARDELVAESGVRLVVAKVQDDIDAGR---VVETIPSRNPMQTFTLLRA 129

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           + +  FDAAFGGARRDEEK+RAKER++SFRD F +WDPKNQRPELW+ YNG+  KGE IR
Sbjct: 130 IRENKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPELWNLYNGRHRKGEHIR 189

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
            FPLSNWTE DIW YI  E I +  +Y A +R V ERDGML+ +  +    +  E I ++
Sbjct: 190 AFPLSNWTEFDIWSYIGAEKIKLPSIYYAHQRKVFERDGMLLAVHKHLQP-RKDEPIIEK 248

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQG-RVIDRDQAGSMELKKRQGY 301
            VRFRT+G    TG VES A T+ E+I E  +S  +ER   R  DR     ME +KR+GY
Sbjct: 249 SVRFRTVGDVTCTGCVESTAATVSEVIAETAISRLTERGATRADDRISEAGMEDRKREGY 308

Query: 302 F 302
           F
Sbjct: 309 F 309


>UniRef50_B5E9A6 Phosphoadenosine phosphosulfate reductase n=3 Tax=Proteobacteria
           RepID=B5E9A6_GEOBB
          Length = 268

 Score =  335 bits (859), Expect = 9e-91,   Method: Composition-based stats.
 Identities = 119/298 (39%), Positives = 170/298 (57%), Gaps = 31/298 (10%)

Query: 6   LTHLRQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           + +L+ LE++S+++IRE   +F     ML+S+GKDS+ +L L RKAF+ G +PFP++H+D
Sbjct: 1   MHYLQALESKSVYVIREAYQKFNGRIAMLWSVGKDSTTLLWLVRKAFF-GKIPFPVMHID 59

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           TG+KF EMYEFRDR AK +G EL+V  N E +A G+ P           +KT  LKQA++
Sbjct: 60  TGYKFPEMYEFRDRLAKEWGFELIVASNKEQLAKGMGPSSGLKLDCCTELKTNALKQAVD 119

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           +YGF +   G RRDE   RAKER +S RD   +WD +NQ  E+W  YN  + + E  R+ 
Sbjct: 120 QYGFQSILLGIRRDEHGIRAKERYFSPRDAEFQWDYENQPAEVWDQYNSFLREDEHYRIH 179

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P+ ++TE DIW+YI  E I IV LY +                                 
Sbjct: 180 PILHFTELDIWRYIQREQIPIVDLYRS-----------------------------NGGK 210

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           R+R++GC P    V S A T+ E+I E+  ST SER GR  D++   +M+  +  GY 
Sbjct: 211 RYRSIGCVPCCNPVPSEAATIEEMIAELETSTDSERAGRAQDKENLYTMQKLRSLGYM 268


>UniRef50_D1J9F7 Sulfate adenylyltransferase subunit 2 n=1 Tax=uncultured archaeon
           RepID=D1J9F7_9ARCH
          Length = 271

 Score =  321 bits (823), Expect = 2e-86,   Method: Composition-based stats.
 Identities = 117/300 (39%), Positives = 172/300 (57%), Gaps = 37/300 (12%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L++LE +SI+I+RE  AEF NP +L+S+GKDS+  L L RKAF  G +PFP++H+DTG+K
Sbjct: 3   LKELENKSIYILREAYAEFENPAILWSMGKDSTTALWLCRKAFL-GEIPFPVIHIDTGYK 61

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
           F++MYEFRDR A+ +G +L++ KN E +  G+ P   G  +    +KTE L   L+K+ F
Sbjct: 62  FKQMYEFRDRIAEEWGFDLVITKNEEAINAGMGP-KDGKLECCTKLKTEALMNYLDKHRF 120

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG-----ESIRV 183
           DA F   RRDE   RAKER++S RD   RW+ ++Q  E+W  Y  Q            RV
Sbjct: 121 DALFLAIRRDEHGIRAKERVFSPRDEEFRWNYRDQPLEMWDQYQTQGRSEKGAVQNHTRV 180

Query: 184 FPLSNWTEQDIWQYIWLE-NIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
            P+ +W E D+W+YI  E +I + P+Y A                               
Sbjct: 181 HPILHWRELDVWEYIKQEKDIPVNPMYFANNGK--------------------------- 213

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
             R+R+LGC P T  ++S A+T+ EI+EE+  +  +ER GR  D+++A  M+  +  GY 
Sbjct: 214 --RYRSLGCEPCTSPIDSTAKTIDEIVEELRTTKVAERSGRAQDKEKAFMMQKLRALGYM 271


>UniRef50_Q07QS4 Sulfate adenylyltransferase subunit 2 n=35 Tax=Bacteria
           RepID=Q07QS4_RHOP5
          Length = 296

 Score =  313 bits (801), Expect = 5e-84,   Method: Composition-based stats.
 Identities = 119/299 (39%), Positives = 165/299 (55%), Gaps = 37/299 (12%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           + HL QLEA+SI+I+RE  A      +L+S+GKDS+VM+ LARKAF+ G +PFP +HVDT
Sbjct: 33  MDHLDQLEAQSIYILREAFARLKKLALLWSLGKDSNVMIWLARKAFF-GRVPFPAMHVDT 91

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNP--EGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           G KF EMY FRD+ +K +  +L++   P  E V   + P    +A      KTEGLK AL
Sbjct: 92  GKKFPEMYAFRDQYSKEWDLDLILEYCPGIESVDPTLPPAARSAA-----RKTEGLKLAL 146

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
            K+GFD    G RRDEE +RAKER++S R     WD ++Q PE W  +N     G  +R+
Sbjct: 147 AKHGFDGLIAGIRRDEEATRAKERVFSPRGTEGGWDVRDQPPEFWDQFNASPPPGSHLRI 206

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            P+ +WTE DIW Y   ENI I+PLYL+                             +  
Sbjct: 207 HPILHWTEADIWAYTKRENIPIIPLYLS-----------------------------QGG 237

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
            R+R+LG   +T  V S A  + EI++E+  +   ER GR +D +   + E  +  GY 
Sbjct: 238 QRYRSLGDADITNPVASTASNIDEILKELDETKVPERAGRALDHETEDAFERLRVAGYL 296


>UniRef50_B3SFD5 Putative uncharacterized protein (Fragment) n=2 Tax=cellular
           organisms RepID=B3SFD5_TRIAD
          Length = 421

 Score =  311 bits (797), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 163/212 (76%), Positives = 183/212 (86%)

Query: 4   IRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
             LTHLRQLEAESIHI REVAAEF NPVMLYS+GKDSSV+LHLARKAF PG +PFPL+HV
Sbjct: 210 PSLTHLRQLEAESIHIFREVAAEFENPVMLYSVGKDSSVLLHLARKAFAPGKIPFPLMHV 269

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           +T WKFREM EFRD+ A+ YG EL+ + NPEG    I PF HGSAK+TDIMKT+ LKQAL
Sbjct: 270 NTTWKFREMIEFRDKMAEKYGFELISYTNPEGADNKITPFTHGSAKYTDIMKTQALKQAL 329

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           +KY FDAAFGGARRDEEKSRAKER++SFRD+ HRWDPKNQRPELW+ YN QINKGESIRV
Sbjct: 330 DKYQFDAAFGGARRDEEKSRAKERVFSFRDKNHRWDPKNQRPELWNIYNAQINKGESIRV 389

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERP 215
           FP+SNWTE DIWQYI++ENI+I  LYLA  RP
Sbjct: 390 FPMSNWTELDIWQYIYMENIEIPSLYLAKPRP 421


>UniRef50_Q13BZ7 Sulfate adenylyltransferase subunit 2 n=7 Tax=Bradyrhizobiaceae
           RepID=Q13BZ7_RHOPS
          Length = 291

 Score =  305 bits (781), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 124/304 (40%), Positives = 167/304 (54%), Gaps = 38/304 (12%)

Query: 2   DQIR-LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +Q+R + HL  LEA+SI+I RE  A      +L+S+GKDS+VM+ LARKAF+ G +PFP 
Sbjct: 23  EQLRPMDHLDALEAQSIYIFREGFARLKKLALLWSLGKDSNVMIWLARKAFF-GRVPFPA 81

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNP--EGVAMGINPFVHGSAKHTDIMKTEG 118
           LHVDTG KF EMY FRD+ +K +  +L V   P  + V   + P    +A      KTEG
Sbjct: 82  LHVDTGKKFPEMYAFRDQYSKEWELDLRVDPCPPIDSVDPTLPPAARSAA-----RKTEG 136

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           LK AL KYGFD    G RRDEE +RAKER++S R     WD ++Q PE W  +N     G
Sbjct: 137 LKLALAKYGFDGLIAGIRRDEEATRAKERVFSPRGTEGGWDVRDQPPEFWDQFNASPPPG 196

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +R+ P+ +WTE DIW Y   ENI I+PLYLA                           
Sbjct: 197 AHLRIHPILHWTEADIWAYTKRENIPIIPLYLA--------------------------- 229

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKR 298
             +   R+R+LG   +T  V SNA ++ EI+ E+  +   ER GR +D +   + E  + 
Sbjct: 230 --QNGKRYRSLGDQDITFPVASNASSIDEILHELQTTKVPERAGRALDHETEDAFERLRV 287

Query: 299 QGYF 302
            GY 
Sbjct: 288 AGYL 291


>UniRef50_Q24TA1 Sulfate adenylyltransferase subunit 2 n=12 Tax=Bacteria
           RepID=Q24TA1_DESHY
          Length = 293

 Score =  302 bits (773), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 112/322 (34%), Positives = 161/322 (50%), Gaps = 54/322 (16%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           + HL +LEA+S++I+RE   EF N  ML+SIGKDS+V+L LARKAF+ G +P PL+H+DT
Sbjct: 1   MNHLDKLEAQSVYILREAYREFKNICMLWSIGKDSTVLLWLARKAFF-GHVPIPLVHIDT 59

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVH--GSAKHTDIMKTEGLKQAL 123
            +K  EM  +RD  A+ +   ++  +N E +  G                +KTE LK  L
Sbjct: 60  HYKIPEMIHYRDELARQWRLTMIYGENKEALDGGRTFPDGKTDRISCCQALKTEALKNTL 119

Query: 124 --------------------NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQ 163
                               N+  +     G R DEE SR+KER +S RD+ + WD  +Q
Sbjct: 120 SGEWSRYILDLETGQYRPDGNREKYTGVIVGVRADEEGSRSKERYFSPRDQENDWDVGDQ 179

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
            PE W+ +      G  IR+ PL +WTE ++W+YI  E I +  LY              
Sbjct: 180 PPEFWNQFKTDFAPGTHIRIHPLLDWTELNVWEYIQREKIPVTSLYF------------- 226

Query: 224 MMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEM---LVSTTSER 280
                           +    R+R+LGC+P T  VES A+ + EIIEE+     +  +ER
Sbjct: 227 ---------------DQGEGKRYRSLGCYPCTLPVESPARNVEEIIEELRSGKFANIAER 271

Query: 281 QGRVIDRDQAGSMELKKRQGYF 302
            GR  D+D  G +E  +R GY 
Sbjct: 272 SGRAQDKDDGGGLETLRRGGYM 293


>UniRef50_B4D6P6 Sulfate adenylyltransferase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D6P6_9BACT
          Length = 283

 Score =  261 bits (666), Expect = 2e-68,   Method: Composition-based stats.
 Identities = 114/230 (49%), Positives = 151/230 (65%), Gaps = 1/230 (0%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           M   +L HL+ LE ESIHI+REVAAEF  P +L+S GKDS  +L LA KAF P  +P P 
Sbjct: 1   MSSYQLDHLQYLETESIHIMREVAAEFERPTILFSGGKDSICLLRLAEKAFRPSDIPMPF 60

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           L+VDTG  F E+ EFRDR A   G +L+V K  + +A GI     G       ++   L 
Sbjct: 61  LNVDTGHHFPELNEFRDRRAAELGGKLIVRKVEDAIASGIAVPTPGEISRNR-LQIPTLL 119

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
            A++++ FD A GGARRDEEK+RAKER +SFRD F +WDP+NQRPE+W+ YN ++N GE+
Sbjct: 120 AAIDEFQFDCAIGGARRDEEKARAKERFFSFRDSFGQWDPRNQRPEIWNVYNARVNPGEN 179

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
           +RVFPLSNWTE DIW+YI  E +++  +Y + +RP       +   D  R
Sbjct: 180 MRVFPLSNWTEMDIWEYIKREKLEVPAIYFSHKRPGGAPRWSVAAGDGYR 229


>UniRef50_A7TD47 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7TD47_NEMVE
          Length = 320

 Score =  216 bits (551), Expect = 6e-55,   Method: Composition-based stats.
 Identities = 88/178 (49%), Positives = 110/178 (61%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            +L QLE E+I+I+RE AA+F NP +L+S GKDS V++HLA KAF PG  PFPL+H+DTG
Sbjct: 6   DYLEQLENEAIYILRETAAQFENPALLFSGGKDSIVLVHLALKAFRPGKFPFPLVHIDTG 65

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
             F E   FRD      G +L+V    E +         G     + ++T  L  A+   
Sbjct: 66  HNFPEAIAFRDYLVNKIGEKLIVASVEESITKYNLKETPGRFPSRNALQTYALLDAIQDN 125

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           GFDA  GGARRDEEK+RAKERI+S RD F +WDPK QRPELW   NG+I   E   V 
Sbjct: 126 GFDACIGGARRDEEKARAKERIFSVRDDFGQWDPKLQRPELWDILNGKIKAIEKNNVS 183


>UniRef50_Q310R0 Phosphoadenylylsulfate reductase (Thioredoxin) n=2
           Tax=Desulfovibrio RepID=Q310R0_DESDG
          Length = 267

 Score =  207 bits (526), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 63/303 (20%), Positives = 108/303 (35%), Gaps = 79/303 (26%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNP---VMLYSIGKDSSVMLHLARKAFYPGTLPFP-- 59
           R+  L Q  A +  ++  + +  + P   V+ ++ GKDS+V+L L R       +  P  
Sbjct: 39  RMIQLSQKTAYARSLLETIISNGTPPSSVVVAWTGGKDSTVVLDLWRNVLRNAGISAPPR 98

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           +L +DTG KF E+  FRD+ A ++   + +   P        P           +K   L
Sbjct: 99  VLSLDTGCKFPEVTTFRDKLAASWQLNMHIVTPP--ADNTGYPVAANVVDCCRRLKVLPL 156

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           + A+          G RRDE  +RA                          +  ++    
Sbjct: 157 QHAVESLNVSILLTGIRRDEHPARAS-----------------------SGHAEKVISPP 193

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
             R+ P+ ++ E D+W Y +   +   PLY                              
Sbjct: 194 HQRLHPIFDFNEMDVWAYTFERQLPYCPLYDEG--------------------------- 226

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQ 299
                 +R+LGC P T    +              ++  ERQGR   ++Q  +M+  +  
Sbjct: 227 ------YRSLGCKPCTSPPTN--------------TSGHERQGRNAVKEQ--NMQTLRSL 264

Query: 300 GYF 302
           GYF
Sbjct: 265 GYF 267


>UniRef50_B1I6V6 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I6V6_DESAP
          Length = 228

 Score =  201 bits (512), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 76/306 (24%), Positives = 116/306 (37%), Gaps = 82/306 (26%)

Query: 1   MDQIRLTH--LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTL 56
           MD+ RL +  L Q EAESI I RE    F        ++ GKDS V+LHL ++A   G +
Sbjct: 1   MDKERLFNWSLEQKEAESIRITRETLERFGTDRVATTFTGGKDSLVLLHLIKQAC-GGRV 59

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
           P  +L +DT   F+E+Y F DR ++ +  +L V +N E +        H   +    +K 
Sbjct: 60  PVRVLKIDTSVDFKEIYAFVDRISREWNLDLHVVRNDEALKTIKTAEDH--VQCCYQLKA 117

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
             L   + ++  +A F   R DE+ +R  E   S R                        
Sbjct: 118 VPLLNFVREHSLEAVFAAIRWDEQDARKDEEYISQR-----------------------Q 154

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
             + +R+ P+ ++ E DIW YI    +    LY                           
Sbjct: 155 NPDHLRMQPILHFREIDIWSYIRKYELPFCELYRRG------------------------ 190

Query: 237 EVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELK 296
                    +R+L C P TG                     SER  R  D++   +M+  
Sbjct: 191 ---------YRSLDCEPCTGR-----------------GGASERGARSRDKE--AAMQRL 222

Query: 297 KRQGYF 302
           +  GYF
Sbjct: 223 REMGYF 228


>UniRef50_C6BYK7 Phosphoadenosine phosphosulfate reductase n=2 Tax=Desulfovibrio
           RepID=C6BYK7_DESAD
          Length = 234

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 70/302 (23%), Positives = 109/302 (36%), Gaps = 85/302 (28%)

Query: 9   LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGT------LPFPL 60
           L    A S  ++  +   +      + ++ GKDS+V+L L R+            L    
Sbjct: 10  LDDKVAHSAGLMSGMLEMYPPERIAVAWTGGKDSTVVLALWREVLKNKGKEASLVLVPQA 69

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           L +DTG KF E+  FRDR A  +G ++ V +    V +   P      K    +K + L+
Sbjct: 70  LSIDTGIKFPEVMAFRDRIALQWGVDVKVIRPD--VDLSSYPIAENPVKCCADLKIKPLQ 127

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           +A++++  D    G RRDE  SRA  R    RD                       + + 
Sbjct: 128 KAIDEFEIDLLITGIRRDEHPSRAGRRFMEVRD-----------------------EPDH 164

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
             + P+  WTE DIW +I +  I    LY                               
Sbjct: 165 TLLNPILEWTEMDIWSFITMHQIPHCELYDQG---------------------------- 196

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
                +R+LGC P T                      SER GR  ++++  ++E     G
Sbjct: 197 -----YRSLGCKPCTAK-----------------GGNSERDGRSAEKER--NLEQLTSMG 232

Query: 301 YF 302
           YF
Sbjct: 233 YF 234


>UniRef50_C3MM97 Phosphoadenosine phosphosulfate reductase n=1 Tax=Sulfolobus
           islandicus L.S.2.15 RepID=C3MM97_SULIL
          Length = 301

 Score =  193 bits (490), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 69/320 (21%), Positives = 114/320 (35%), Gaps = 90/320 (28%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L      +  +I      F   V+++S GKDS++ L+ ARK       P   + +D    
Sbjct: 46  LEYKAKIAELVIEAAYNTFKRVVVVWSGGKDSTLSLYFARKVSEKLGKPLEAIIIDHYMH 105

Query: 69  FREMYEFRDRTAKAYGCELLVHKNP------------------------EGVAMGINPFV 104
           F E ++F D   K +   L+V  N                         E V    + F+
Sbjct: 106 FDETWKFIDEVKKDWNVNLIVKGNERLKGHKYGDVIKISDLSEKDRKELENVGYSKDTFL 165

Query: 105 H--GSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
           +   +     ++KT  LK+A+ +Y  DA   G R DE  +R+ E  +S R+         
Sbjct: 166 YALNNIAANHLLKTVPLKEAIEEYNIDALIVGDRWDENPARSTETFFSARE--------- 216

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
                           +  RV P+  +TE+D+W +I    + I PLY    R +      
Sbjct: 217 --------------NPKHFRVHPILLFTERDVWNFILTNKLPIHPLYYKGFRSI------ 256

Query: 223 LMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQG 282
                D++ + +P +                                 E  +  T ER G
Sbjct: 257 -----DDKYETKPTDTKPAW----------------------------EQDLENTPERAG 283

Query: 283 RVIDRDQAGSMELKKRQGYF 302
           R  D++    ME+ +R GY 
Sbjct: 284 RAQDKENI--MEILRRHGYM 301


>UniRef50_Q72BR8 Phosphoadenosine phosphosulfate reductase, putative n=5
           Tax=Desulfovibrionales RepID=Q72BR8_DESVH
          Length = 255

 Score =  190 bits (483), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 67/306 (21%), Positives = 100/306 (32%), Gaps = 81/306 (26%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPF 58
           + +  +  L    A +  ++ EVA  +      + ++ GKDS+V L L ++         
Sbjct: 27  LRRPSVEGLELKVARARRVLLEVAHTWKPQDVAVAWTGGKDSTVALSLWQRVLDEAHPGM 86

Query: 59  --PLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
               L +DTG KF E+  FRDR A+ +  +L V +   G      P           +K 
Sbjct: 87  RAKALSLDTGCKFPEVVAFRDRMAQEWSIDLTVVRPDVGPDY---PVAVDRVACCRDLKV 143

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           E L +AL +        G R DE   RA                               +
Sbjct: 144 EPLLRALKEREIAVLLTGVRADENPERASRP-----------------------QTETFD 180

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
               +RV P+  ++E DIW Y   + +    LY                           
Sbjct: 181 APSHVRVHPVLEFSEMDIWAYTMAQGLPYCTLYAQG------------------------ 216

Query: 237 EVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELK 296
                    +R+LGC P T                 LV    ER GR  D  +  SM+  
Sbjct: 217 ---------YRSLGCVPCTS----------------LVVGGDERAGR--DATKEASMDAL 249

Query: 297 KRQGYF 302
              GYF
Sbjct: 250 HALGYF 255


>UniRef50_C7NUQ7 Phosphoadenosine phosphosulfate reductase n=12 Tax=Halobacteriaceae
           RepID=C7NUQ7_HALUD
          Length = 325

 Score =  188 bits (476), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 68/325 (20%), Positives = 126/325 (38%), Gaps = 71/325 (21%)

Query: 15  ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP-LLHVDTGWKFREMY 73
           ++I + +    ++ NPV++++ GKDS++ L+  ++      L  P ++ +D    F E+ 
Sbjct: 35  KAIEVTKTGLEQYDNPVVMWTGGKDSTLTLYFVKEVADRFDLEVPPVVFIDHYQHFDELI 94

Query: 74  EFRDRTAKAYGCELLVHKNPE--------GVAMGIN------------------------ 101
           +F    A+ +  E++  +N +        G+  G +                        
Sbjct: 95  DFCKHWAEEWDLEIIWARNTDVGDYVDENGLEPGDDIPVDALSEHNQHHIRNILEYEEDT 154

Query: 102 -PFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP 160
            PF+  +     ++KT  L  A+ ++  D    G R DE+++RA E  +S R      DP
Sbjct: 155 FPFLLDTYVGNHLLKTVALNDAIEEHDVDGILSGVRWDEQEARADETFFSPRH-----DP 209

Query: 161 KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
               P                R+ P+  + E D+W+  W   +                +
Sbjct: 210 DIYPP--------------HDRIQPILQFAEADVWEAFWNFVVP-------DTVEEFPEE 248

Query: 221 GMLMMIDDNRIDLQPGE---VIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTT 277
           G +    ++  D    E   V  K    FR+LG    T      A   P  +++M  + T
Sbjct: 249 GYVPQGSEDLPDGLTKEDVPVSPKYFAGFRSLGSEVST----DKAAEEPAWLQDM--ANT 302

Query: 278 SERQGRVIDRDQAGSMELKKRQGYF 302
           +ER GR  D++    ME  +  GY 
Sbjct: 303 TERAGRAQDKEDL--MERLRDLGYM 325


>UniRef50_D2EEN4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Parvarchaeum acidiphilum ARMAN-4 RepID=D2EEN4_9EURY
          Length = 276

 Score =  183 bits (465), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 72/322 (22%), Positives = 119/322 (36%), Gaps = 92/322 (28%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYP-GTLPFPLLHVDTGW 67
           L   E  ++ +I++    ++ P +++S GKDS+V+L L R+A    G    P L +D G 
Sbjct: 19  LEAKEDIALIVIKDALKRYNRPTVVWSAGKDSTVVLDLVRRACKDLGMQLPPALFIDHGQ 78

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVA----------MGINPFVHGSAKH------- 110
            + E  +  +  +K +G +++  KN + +             +N      AK        
Sbjct: 79  HYDETMKMLEDISKGWGFKMVYAKNEDVIKNVGKDNKIKLSSLNKINQDEAKRIGFNGEE 138

Query: 111 ----------TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP 160
                       ++KT  +  A+ KY FDA F G R DE ++R+ E   S R        
Sbjct: 139 FEYSLETEIGNHLLKTVAMNMAIEKYRFDALFTGVRWDENEARSTEVFISPRT------- 191

Query: 161 KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
                             + +RV P+  + E+++W+YI+   +   PLY    R +   D
Sbjct: 192 ----------------HPDHVRVQPILPFAERNVWEYIFKYKLPTHPLYKLGYRSI---D 232

Query: 221 GMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSER 280
           G L                                         LP    E  +  T ER
Sbjct: 233 GKLD----------------------------------SKKTSDLPAW--EQDLEHTKER 256

Query: 281 QGRVIDRDQAGSMELKKRQGYF 302
            GR  D++  G ME  +  GY 
Sbjct: 257 AGRSQDKE--GVMEKLRLFGYM 276


>UniRef50_C0QUE3 Phosphoadenosine phosphosulfate reductase n=1 Tax=Persephonella
           marina EX-H1 RepID=C0QUE3_PERMH
          Length = 235

 Score =  183 bits (464), Expect = 7e-45,   Method: Composition-based stats.
 Identities = 53/286 (18%), Positives = 93/286 (32%), Gaps = 81/286 (28%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           + R  H   L A+   +++ V   F N     S   D   ++H+ ++          ++ 
Sbjct: 8   KERSDHFENLPAQ--DLLKWVYQNFKNVGFTSSFSADDVSIIHMIKEI----KPDALIIF 61

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTE 117
           +DT + F E YE   +  + +   L + K       +    G   +     K   I K E
Sbjct: 62  IDTDYHFPETYELVKKIKEEWDINLKIIKPLITVEEQDRLYGEKLYEKDPDKCCQIRKVE 121

Query: 118 GLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
            LK+ L +   D    G RRD+  +RA                           +   + 
Sbjct: 122 PLKRVLEE--LDVWITGMRRDQSPTRANIGKVE--------------------THRLPSG 159

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
              ++V P+++WT +D+W+Y+   N+   PLY                            
Sbjct: 160 KTILKVNPIADWTRKDVWKYVHENNLPYNPLYDQN------------------------- 194

Query: 238 VIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                   + ++GC P T  V               +    ER GR
Sbjct: 195 --------YLSIGCAPCTRPV---------------LEGEDERAGR 217


>UniRef50_A9S2B6 Predicted protein n=3 Tax=Embryophyta RepID=A9S2B6_PHYPA
          Length = 326

 Score =  176 bits (445), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 50/255 (19%), Positives = 93/255 (36%), Gaps = 38/255 (14%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +Q R   L+ LEA+++  +++    F  P    ++     V+L L  +          ++
Sbjct: 84  EQARDARLQHLEAQALETLQKTVENFEKPAFPCALIAGDVVILDLLHRIGAFSDNKVKII 143

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE-------GVAMGINPFVHGSAKHTDIM 114
            +DT   F E Y+F     + YG +  V    +           G + F+    ++  I 
Sbjct: 144 FIDTFHLFPETYKFLSEVEERYGFKAHVFHAADVNNKEAYDAKFGSDLFITDIEEYDRIC 203

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E   +AL     DA   G RRD    RA   ++                         
Sbjct: 204 KVEPFSRALKTLEVDAMINGRRRDHGAERAHLEVFE------------------------ 239

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
             +G+ ++V PL+ W  +D W Y+   ++   PL+      + +    + +  +      
Sbjct: 240 --EGKMVKVQPLAYWEFRDCWDYLTKYSLPYHPLHDQGFPSIGDVQSTIPVPREKWF--- 294

Query: 235 PGEVIKKRMVRFRTL 249
             E   +R  RF+ L
Sbjct: 295 --EYAGERSGRFQGL 307


>UniRef50_Q1ITG5 Phosphoadenylylsulfate reductase (Thioredoxin) n=5 Tax=Bacteria
           RepID=Q1ITG5_ACIBL
          Length = 234

 Score =  175 bits (443), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 55/252 (21%), Positives = 91/252 (36%), Gaps = 63/252 (25%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
            +   A +  +++E       P +  S   +  V+L L R+         P+L +DTG+ 
Sbjct: 10  FQAKIAAAQALVQESIEHAKRPCLTCSFQAEDVVVLDLLRQVV----PDIPVLFLDTGYH 65

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPF----VHGSAKHTDIMKTEGLKQALN 124
           F E+Y++RD  A  +   L+     + VA   + F         +     K E L +AL 
Sbjct: 66  FAEVYQYRDEIASKWRLNLINLLPKQSVAEQESAFGILYQTAPDRCCGARKVEPLFRALE 125

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            Y     F G RR++ KSR+                  Q  +L+    G     E  +V 
Sbjct: 126 NY--STWFTGLRREQSKSRSAL----------------QSIDLFTLPTGT----EIQKVS 163

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL+ W+ +D+W Y     I ++PLY                                   
Sbjct: 164 PLAEWSTRDVWTYASAHGIPLLPLYEKG-------------------------------- 191

Query: 245 RFRTLGCWPLTG 256
            + ++GC P T 
Sbjct: 192 -YSSIGCEPCTS 202


>UniRef50_C0GLN5 Phosphoadenosine phosphosulfate reductase n=1
           Tax=Desulfonatronospira thiodismutans ASO3-1
           RepID=C0GLN5_9DELT
          Length = 186

 Score =  174 bits (440), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 60/262 (22%), Positives = 94/262 (35%), Gaps = 78/262 (29%)

Query: 43  MLHLARKAFYPGTLPFPL--LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI 100
           MLH              +  L++DTG+KF E+ EFRD  A  +G EL V           
Sbjct: 1   MLHQWMIFLQERGPGVQVRALNLDTGYKFPEVLEFRDEMAWEWGLELTVAGPDSSAMQ-- 58

Query: 101 NPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP 160
           +       +    +K   L++A+ ++G      G RRDE  SR                 
Sbjct: 59  DLQELSKVECCRRLKVSPLQEAVREHGVRVLLTGIRRDEHPSRENTPDVQ---------- 108

Query: 161 KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
                        + N  +  +V P+++WTE DIW YI L+ +    LY A         
Sbjct: 109 -------------EKNDLDYYQVNPIAHWTEMDIWSYIMLKGLPYCSLYDAG-------- 147

Query: 221 GMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSER 280
                                    +R+LGC P T                +  +  +ER
Sbjct: 148 -------------------------YRSLGCKPCT----------------VKGTHMNER 166

Query: 281 QGRVIDRDQAGSMELKKRQGYF 302
            GR  DR++  ++++ +  GYF
Sbjct: 167 SGR--DREKEENLDMLRSMGYF 186


>UniRef50_Q0W1C8 Putative 3\'-phosphoadenosine 5\'-phosphosulfate sulfotransferase
           (PAPS reductase) n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W1C8_UNCMA
          Length = 641

 Score =  173 bits (439), Expect = 5e-42,   Method: Composition-based stats.
 Identities = 58/223 (26%), Positives = 85/223 (38%), Gaps = 35/223 (15%)

Query: 8   HLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
            L+ +EA++I +IR VA +  N    + +S GKDS V+ ++ARKA            VDT
Sbjct: 221 RLQSMEADAISVIRGVAGQHKNLPVTVSFSGGKDSLVVFNIARKAVN----KLKAFFVDT 276

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVA---MGINPFVHGSAKHTDIMKTEGLKQA 122
           G +F E  EF +R A   G E+ V +  +          P          + K   +   
Sbjct: 277 GLEFPETSEFVERFAHDTGVEITVQRAGDAFDQNFPAFGPPAKDFRWCCKVCKLGPITSL 336

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           LN         G RR E   R        R+ F                         I 
Sbjct: 337 LNNSKGVITIDGKRRYESFQRGHIGTVE-RNPF---------------------VPGQIG 374

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           VFP+ +W   ++W YI++E +   PLY        ER G  + 
Sbjct: 375 VFPVKDWRAIEVWLYIYMEKLPYNPLYDLG----FERIGCWLC 413


>UniRef50_D1YW88 Putative phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocella paludicola SANAE RepID=D1YW88_METPS
          Length = 632

 Score =  169 bits (429), Expect = 7e-41,   Method: Composition-based stats.
 Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 35/233 (15%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
            +L  +E E+I   ++VA ++  PV + YS GKDS   L L RKA       F +L+++T
Sbjct: 225 EYLMSIEGEAIGFAKKVAGQYRLPVTVSYSGGKDSLATLLLVRKAL----PDFDVLYINT 280

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           G +F E  +        YG  L   K       A  + P    +     + K   +   +
Sbjct: 281 GLEFPETTQNVHDVVAQYGLRLKTAKAGSFWDAAPSLGPPSVEARWCCKVCKLGPITDLI 340

Query: 124 NKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
                D    F G RR E + RAK +                   +W N       G  +
Sbjct: 341 ENNYSDGCLTFIGQRRYESEVRAKSQ------------------RIWQN----PWVGNQV 378

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
              P+ +WT   IW Y++ E     PLY        +R G  +    +  D +
Sbjct: 379 SASPIQHWTALHIWLYLFREKAPYNPLYGRG----FDRIGCWLCPSASLADYE 427


>UniRef50_A1RXY7 Phosphoadenosine phosphosulfate reductase n=1 Tax=Thermofilum
           pendens Hrk 5 RepID=A1RXY7_THEPD
          Length = 614

 Score =  168 bits (426), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 63/234 (26%), Positives = 95/234 (40%), Gaps = 34/234 (14%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLY-SIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
            +L   EAE++  IREVA ++  PV +  S GKDS V LHLA KA   G      L  +T
Sbjct: 209 EYLLAKEAEAVSFIREVAEKYRLPVFVSLSGGKDSLVTLHLAVKAL--GNEKVKALFNNT 266

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMG---INPFVHGSAKHTDIMKTEGLKQA 122
           G +F E  E+  R A  YG EL+     +        + P          + K   + +A
Sbjct: 267 GLEFEETVEYARRIADYYGVELIEADAGDNFWRALPVMGPPARDYRWCCKVTKFSTISRA 326

Query: 123 LNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           + K+  + A    G R+ E  +RA                    P +W NY         
Sbjct: 327 VKKFFPEGALSLVGQRKYESSARA------------------LSPRIWRNY----WLPGV 364

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
           +   P+ +W+  DIW YI++E + +  LY        +R G  +       +L 
Sbjct: 365 VAASPVHDWSAMDIWLYIFMERLPVNKLYYYG----FDRLGCWLCPASEMGELD 414


>UniRef50_D2R2B5 Phosphoadenosine phosphosulfate reductase n=5 Tax=Planctomycetales
           RepID=D2R2B5_9PLAN
          Length = 273

 Score =  167 bits (423), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 66/280 (23%), Positives = 103/280 (36%), Gaps = 84/280 (30%)

Query: 11  QLE-AESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           +LE A    I+R   A F+    M  + G +  V+LH+  + F P T   P+ ++DTG++
Sbjct: 57  ELETATPQEILRWSIARFAPKFTMATAFGPEGMVILHMLSE-FAPET---PIFNLDTGYQ 112

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAM-----GINPFVHGSAKHTDIMKTEGLKQAL 123
           F E    RD  A+ YG E+ + +    V       G   + H   +     K E L++A+
Sbjct: 113 FPETLALRDEVARRYGMEVELKRATLSVEEYEAQNGGPVYRHSPDRCCHNRKVEVLEKAV 172

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G  A     RRD+   RAK  I  +  +F                         ++V
Sbjct: 173 --LGQHAWASAIRRDQSPDRAKAPIVGWDKKFGL-----------------------VKV 207

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL+NWT++ +W +I   N+   PL+                                  
Sbjct: 208 SPLANWTKKQVWTHITEHNVPYNPLHDNG------------------------------- 236

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
             + ++GCWP T AV                    ER GR
Sbjct: 237 --YTSIGCWPCTRAV---------------GVGEDERAGR 259


>UniRef50_A1SC70 Phosphoadenylylsulfate reductase (Thioredoxin) n=1 Tax=Nocardioides
           sp. JS614 RepID=A1SC70_NOCSJ
          Length = 229

 Score =  167 bits (422), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 59/266 (22%), Positives = 100/266 (37%), Gaps = 65/266 (24%)

Query: 1   MDQIRLTHLRQLEAESI-HIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           +  +   H  +LE  S   ++R     F   +   S   D+++  HLA  +  PG     
Sbjct: 11  LQAVVFEHAEELEGVSADSVVRWARDTFGTKLCATSSMSDAAIT-HLA-SSCAPG---LD 65

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           +L +DTG+ F E   FRD+ A A+   ++  ++       I P+   S     + K   L
Sbjct: 66  VLFLDTGYHFPETLAFRDQVAAAFDVRVVDLRSKPAPGNQIPPWSTDSNDCCRLRKVVPL 125

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           +QAL   G+DA   G RR E  SR++  + S       WD  NQ                
Sbjct: 126 RQALA--GYDAWLTGIRRAESPSRSQTPVVS-------WDSHNQ---------------- 160

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
            ++V PL+ WT++ +  Y+    +    L                               
Sbjct: 161 VVKVAPLAAWTDEALAAYLHEHALPGNRLTELG--------------------------- 193

Query: 240 KKRMVRFRTLGCWPLTG-AVESNAQT 264
                 + ++GC P T   V ++A++
Sbjct: 194 ------YPSIGCEPCTSLPVGTDARS 213


>UniRef50_C6D4K6 Adenylylsulfate reductase, thioredoxin dependent n=2 Tax=Bacillales
           RepID=C6D4K6_PAESJ
          Length = 231

 Score =  166 bits (419), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 47/222 (21%), Positives = 86/222 (38%), Gaps = 36/222 (16%)

Query: 2   DQIRLTHLRQLEAESI-HIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           + +      +LE  +   I+      F N     S G +  V++ + +K     +    +
Sbjct: 7   EALVKQKAEELENATPQEILAYAVEAFPNITFACSFGAEDVVLVDMLQKV----SPKTDI 62

Query: 61  LHVDTGWKFREMYEFRDRTAKAY------GCELLVHKNPEGVAMGINPFVHGSAKHTDIM 114
            ++DT + F+E YE RDR  + Y        + L+    +    G   +   +    +I 
Sbjct: 63  FYLDTDFHFKETYETRDRMVERYPGIPFVEVKPLITPEEQAERHGAELWKSDANACCNIR 122

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E L + L+KY  DA   G RRD+  +RA  +   +  +F                   
Sbjct: 123 KVEPLTRILSKY--DAWITGIRRDQAPTRANAKKVEYDTKFGL----------------- 163

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
                 I+  P++ WT +D+W YI   ++   PL+      +
Sbjct: 164 ------IKFNPIAGWTTEDVWNYIRENDVIYNPLHDQNYPSI 199


>UniRef50_Q0W3A3 Putative 3\'-phosphoadenosine 5\'-phosphosulfate sulfotransferase
           (PAPS reductase) n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W3A3_UNCMA
          Length = 627

 Score =  165 bits (417), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 58/237 (24%), Positives = 88/237 (37%), Gaps = 35/237 (14%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLL 61
                ++   E+E I   + VAAE + PV + YS GKDS   L + RKA       F ++
Sbjct: 214 AANANYIDGFESEGISFAKRVAAEKNLPVTVSYSGGKDSLATLLIVRKAL----PDFDVM 269

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGL 119
           +++TG +F E        A+ Y  +L V +       A    P    +     + K   +
Sbjct: 270 YINTGLEFPETTANVHEVAEKYQLKLKVAEAESFWAAAPKFGPPSVEARWCCKVCKLGPI 329

Query: 120 KQALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
              +     +    F G RR E + RAK    S R   + W                   
Sbjct: 330 TDLIENSYPEGCLSFIGQRRYESEVRAK----SLRVWQNPW------------------V 367

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
           G  I   P+ NWT   IW Y++ E     PLY        +R G  +    +  D +
Sbjct: 368 GNQISASPIQNWTALHIWLYLFREKAPYNPLYERG----FDRIGCWLCPSASLADYE 420


>UniRef50_C8WSE6 Adenylylsulfate reductase, thioredoxin dependent n=2
           Tax=Alicyclobacillus acidocaldarius RepID=C8WSE6_ALIAD
          Length = 234

 Score =  164 bits (416), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 49/229 (21%), Positives = 76/229 (33%), Gaps = 39/229 (17%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           EA    I+RE      N     S G +  V+L +             + ++DT   F E 
Sbjct: 20  EARPEDILREALRRVPNITFACSFGAEDMVILDMLMSI----DQQADVFYLDTNVLFPET 75

Query: 73  YEFRDRTAKAYGCELLVHKNP------EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           YE  +R    YG   L    P      +    G   +         I K E L   L   
Sbjct: 76  YELIERAVAKYGIPNLHQVLPKLTLEEQAAQYGDALWSRDPNLCCKIRKVEPLAAFLA-- 133

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           G+D    G RR++  +R   +++ +  +F                         ++V PL
Sbjct: 134 GYDGWITGIRREQAPTRRNAKVFEWDAKF-----------------------NIVKVNPL 170

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
             WTE+D+W YI    +   PL+      +    G L      +    P
Sbjct: 171 VRWTEKDVWNYIVERGVPYNPLHDRNYPSI----GCLHCTRPVKPGEDP 215


>UniRef50_A2SQI0 Phosphoadenosine phosphosulfate reductase n=3
           Tax=Methanomicrobiales RepID=A2SQI0_METLZ
          Length = 472

 Score =  164 bits (415), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 60/235 (25%), Positives = 87/235 (37%), Gaps = 36/235 (15%)

Query: 9   LRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           L   E +SI  I +V A+     P + YS GKDS V L +  KA     L  PL+  DTG
Sbjct: 219 LDLYERKSIEFIHDVIAKNPGIQPTVSYSGGKDSLVTLLITLKA----GLRLPLIFADTG 274

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMG---INPFVHGSAKHTDIMKTEGLKQAL 123
            +F E  E   + ++ +   L++     G   G     P            K   +K  +
Sbjct: 275 LEFPETIENVQKVSELFDLPLIIESGNSGFWEGFELQGPPAVDFRWCCKACKLTPVKTLI 334

Query: 124 N-KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
             K+G   +F G R+ E   R                   Q P +W N N        I 
Sbjct: 335 ENKWGEAISFIGQRKFESAKRM------------------QSPRVWRNRNVPC----QIS 372

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
             P+ +WT    W Y++ E     PLY       L+R G  M    +   ++  E
Sbjct: 373 AAPIQHWTAMHDWLYLFREKAPYNPLYELG----LDRIGCFMCPSSDIACMKDIE 423


>UniRef50_A9AB03 Phosphoadenosine phosphosulfate reductase n=7 Tax=Methanococcus
           RepID=A9AB03_METM6
          Length = 512

 Score =  162 bits (410), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 56/241 (23%), Positives = 95/241 (39%), Gaps = 33/241 (13%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLP-- 57
           M +     ++++E+ SI  +R    +   P  + YS GKDS  +L LA +AF     P  
Sbjct: 240 MIEANKNAMQKVESNSIGFMRNTVVKIGRPASVAYSGGKDSLTVLLLALEAFKNHEDPIE 299

Query: 58  FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMK 115
           F +L  DTG +F E  E  ++ AK YG E+L   + E         P    +   +++ K
Sbjct: 300 FNVLFNDTGIEFNETLENIEKIAKLYGIEILKTSSGEFWEKLEEYGPPGRDNRWCSEVCK 359

Query: 116 TEGLKQALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
              L   +++        F G R+ E  +R+K                  +P +W++   
Sbjct: 360 VSPLGTLIDEKYEKGCLSFVGLRKYESINRSK------------------KPRIWNSPTI 401

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
           +     +    P+ NWT   +W YI         LY        +R G  M       ++
Sbjct: 402 KKQMLSA----PILNWTAMHVWIYILKHKAPYNVLYEQC----FDRVGCFMCPAMEIGEI 453

Query: 234 Q 234
           +
Sbjct: 454 E 454


>UniRef50_B6ASY4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Rhodobacterales
           bacterium HTCC2083 RepID=B6ASY4_9RHOB
          Length = 243

 Score =  161 bits (406), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 57/256 (22%), Positives = 93/256 (36%), Gaps = 67/256 (26%)

Query: 10  RQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
           R LEA S   + +   +     ++   G DS+V+LHLA +         P+L +DTG  F
Sbjct: 15  RALEATSAIRLGQSDPQVGQIALVSGFGADSAVLLHLAAQLV----PDMPVLFLDTGKHF 70

Query: 70  REMYEFRDRTAKAYGCELLVHKNPEGVAMGIN-----PFVHGSAKHTDIMKTEGLKQALN 124
            E  +++   A   G + L    P+  A+         + H      D+ KT+ L  AL 
Sbjct: 71  NETLQYQRELASELGLQDLRTIKPDANAIAETDPYGALYSHAPDACCDLRKTQPLTLALK 130

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             GFD    G +R +  SRAK  ++    +                        + +++ 
Sbjct: 131 --GFDGWITGRKRHQSVSRAKMNVFEIDGQ-----------------------SQQLKIN 165

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL++W+ QD+ QY+    +   PL                                    
Sbjct: 166 PLAHWSAQDVAQYMRDHALLPHPL---------------------------------VAR 192

Query: 245 RFRTLGCWPLTGAVES 260
            F ++GC P T A  S
Sbjct: 193 GFLSIGCSPCTSATLS 208


>UniRef50_Q9YA63 Putative uncharacterized protein n=1 Tax=Aeropyrum pernix
           RepID=Q9YA63_AERPE
          Length = 464

 Score =  159 bits (402), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 29/219 (13%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           LR LE  S  ++R V  +    ++ +S GKDS+  L LA +AF  G      ++VDTG  
Sbjct: 220 LRVLEQHSAEVLRMVGEDVDTVIVPWSGGKDSTAALLLAVEAF--GRDAVKAVYVDTGID 277

Query: 69  FREMYEFRDRTAKAYGCELLVHKN--PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           F E  E+ ++ A   G +L+  +    EG+ +   P      +     K E L+QA    
Sbjct: 278 FIENAEYVEKVASTLGVDLVYARADVDEGLLIEGMPMPDPEYRWCTGRKLEALRQAFRTV 337

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
                          SR K  + +  DR    + + +RP L ++      K     V PL
Sbjct: 338 ---------------SRGKTVVVT-GDRDGESEKRGKRPPLRYD-----EKLGYPVVSPL 376

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
             W+   +  YI  + I + PLY A       R G  + 
Sbjct: 377 KLWSGGHVQLYILSKGIPLNPLYEAG----FYRIGCYLC 411


>UniRef50_Q58383 Uncharacterized protein MJ0973 n=11 Tax=Methanococcales
           RepID=Y973_METJA
          Length = 411

 Score =  158 bits (400), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 54/225 (24%), Positives = 86/225 (38%), Gaps = 36/225 (16%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVML----YSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
             + +LE +S+ II++      N        +S GKDSSV   LA K          ++ 
Sbjct: 154 DRIEKLEKKSLSIIKKYYEMCKNKNYAINTSFSGGKDSSVSTLLANKVI----DDLEVIF 209

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGLK 120
           +DTG +F++  +F  + AK Y   L+V K                       + K E LK
Sbjct: 210 IDTGLEFKDTIDFVKKFAKKYDLNLVVLKGKNFWEYLEKEGIPTKDYRWCNSVCKLEPLK 269

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           + L KY       G+RR E  +R K    ++  +    +                     
Sbjct: 270 EYLKKYKRVYTIDGSRRYESFTREK---LTYERKSGFIE-------------------NQ 307

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           I +FP+ +W   D+W +I+L ++    LY        ER G  M 
Sbjct: 308 INIFPILDWRGTDVWSWIYLNDVIYNELYDKG----FERIGCYMC 348


>UniRef50_Q55309 Phosphoadenosine phosphosulfate reductase n=3 Tax=Bacteria
           RepID=CYSH_SYNE7
          Length = 232

 Score =  157 bits (396), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 52/258 (20%), Positives = 93/258 (36%), Gaps = 47/258 (18%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           +  +   + +  +  +  II+  A EF    V+  S G  S+VMLHLA +         P
Sbjct: 5   LPSLTEINAQLADQAATQIIQWAATEFGSGLVLSTSFGIQSAVMLHLATQV----QPDIP 60

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPF--------VHGSAKHT 111
           ++ +DTG+   E Y F     +     L V+++    A     +        V    ++ 
Sbjct: 61  VIWIDTGYLPTETYRFAAELTERLKLNLKVYQSEISPARMEALYGRLWESESVEDFNRYD 120

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            + K E + +AL + G  A   G RR +   R    I                       
Sbjct: 121 QMRKVEPMNRALQELGATAWLSGVRRQQTAHRQSMEIVEL-------------------- 160

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                K +   + P+  W  +D++QY+   ++   PL+           G + + D +  
Sbjct: 161 -----KRDRYAIRPILGWHSRDVYQYLTAHDLPYHPLFDQ---------GYVTVGDWHSS 206

Query: 232 DLQPGEVIKKRMVRFRTL 249
                +   +R  RFR L
Sbjct: 207 RPLQADDSDERSTRFRGL 224


>UniRef50_Q2JFN1 Phosphoadenylylsulfate reductase (Thioredoxin) n=1 Tax=Frankia sp.
           CcI3 RepID=Q2JFN1_FRASC
          Length = 223

 Score =  156 bits (395), Expect = 7e-37,   Method: Composition-based stats.
 Identities = 50/254 (19%), Positives = 89/254 (35%), Gaps = 69/254 (27%)

Query: 10  RQLE-AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
             LE A +  I+R    EF   + + +   ++ ++  LAR          P++ +DTG+ 
Sbjct: 14  DDLEGAPAEEILRWAVGEFGTKLAIAASMAEAILVDMLARI-----RSDVPVVFIDTGYH 68

Query: 69  FREMYEFRDRTAKAYGCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           F E    RD  A  Y   ++  +       +    G + +         + K   L +AL
Sbjct: 69  FPETVGTRDAVAGTYDLPIISARPQLTVVGQDAVYGQDLYRTDPDLCCRMRKVVPLDRAL 128

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
             Y   A   G+RR E  SRAK R+  +  R  +                       +++
Sbjct: 129 APYR--AWAAGSRRAESPSRAKLRVVDWDARRGK-----------------------VKI 163

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL+ WT++D+ +Y+    + + PL                                   
Sbjct: 164 HPLAAWTDEDVERYVAEHGVIVNPL---------------------------------LS 190

Query: 244 VRFRTLGCWPLTGA 257
             + ++GCWP T  
Sbjct: 191 DGYDSVGCWPCTRR 204


>UniRef50_P72794 Phosphoadenosine phosphosulfate reductase n=23 Tax=Bacteria
           RepID=CYSH_SYNY3
          Length = 249

 Score =  156 bits (394), Expect = 9e-37,   Method: Composition-based stats.
 Identities = 46/235 (19%), Positives = 87/235 (37%), Gaps = 39/235 (16%)

Query: 11  QLEAESIHIIREVAAEFSNP--VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           +LE  +   I   AA+   P  VM  S G  ++VMLHL            P++ +DTG+ 
Sbjct: 16  ELENATAQQIITWAAQTFGPGLVMSTSFGIQAAVMLHLVTSIVPN----IPVIWIDTGYL 71

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPF--------VHGSAKHTDIMKTEGLK 120
             E Y+F D+        L V+++P   A     +        V    ++  I K E ++
Sbjct: 72  PLETYQFADQLTGRLQLNLKVYQSPLSPARMEALYGKLWQQKDVESLNRYDQIRKVEPMQ 131

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           +AL +    A   G RRD+ + R   +                             +G  
Sbjct: 132 RALKELEAIAWLTGLRRDQTRHRQNLKPVDL-------------------------QGNQ 166

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
            +V P+ +W  + +++Y+   ++   P +      V +      ++  +  +   
Sbjct: 167 YKVLPILDWNSKMVYEYLTAHDLPYHPFFDQGYVSVGDWHSSRPLMAHDEDERDT 221


>UniRef50_C5U5U5 Phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocaldococcus infernus ME RepID=C5U5U5_9EURY
          Length = 395

 Score =  155 bits (391), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 53/221 (23%), Positives = 84/221 (38%), Gaps = 35/221 (15%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
             + +LE ++ ++I+    +  N    +S GKDSSV   LA +          ++ +DTG
Sbjct: 149 NRIEKLEKKAKNLIKNYKGKEIN--ASFSGGKDSSVSTLLANEIIK----DIEVIFIDTG 202

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
            +F E  +F    AK Y   L + K  +              +     I K   L++ L 
Sbjct: 203 LEFPETIKFVKDFAKKYDLNLTILKGGDFWEELNKRGVPTKDNRWCNTICKLNPLREYLK 262

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           KY       G+RR E  SR +                        +Y  +      I VF
Sbjct: 263 KYKLVYTINGSRRAESFSRERL-----------------------SYEKRGLIENQINVF 299

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           P+ +W   D+W +I+L +I   PLY        ER G  + 
Sbjct: 300 PILDWKGVDVWSWIYLNDILYNPLYDKG----FERIGCYLC 336


>UniRef50_Q11B66 Phosphoadenosine phosphosulfate reductase n=36
           Tax=Alphaproteobacteria RepID=CYSH_MESSB
          Length = 245

 Score =  154 bits (390), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 54/253 (21%), Positives = 88/253 (34%), Gaps = 72/253 (28%)

Query: 15  ESIHIIREVAAEFSN---PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
            +  I+      F +      + S G DS+V+LH+            P+L +DTG  F E
Sbjct: 25  AAEAIVELAVNRFRDEGGIATVSSFGADSAVLLHMVASV----DKSLPVLFLDTGQHFGE 80

Query: 72  MYEFRDRTAKAYGCELLVHKNPEG-----VAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
             E+RD+ A   G   LV  +P+         G +     S    +I K E + +A+  Y
Sbjct: 81  TIEYRDQLASDLGLSNLVVVHPKSEMLSARDPGNDLHKSDSDLCCEIRKVEPMARAVEPY 140

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
              A F G +R + +SRA+  ++                            G  IR+ PL
Sbjct: 141 --SAWFTGRKRHQAESRAQMPVFE-------------------------AVGPRIRINPL 173

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
           + WT  D   Y+   ++   PL                                     +
Sbjct: 174 ARWTTADQAAYMRANDLRENPL---------------------------------VAYGY 200

Query: 247 RTLGCWPLTGAVE 259
            ++GC+P T  V+
Sbjct: 201 LSIGCFPCTQPVK 213


>UniRef50_C1A1H0 Phosphoadenosine phosphosulfate reductase n=21 Tax=Actinomycetales
           RepID=CYSH_RHOE4
          Length = 247

 Score =  154 bits (390), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 47/236 (19%), Positives = 87/236 (36%), Gaps = 47/236 (19%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGK---------DSSVMLHLARKAFYPGTLPFPLLHVD 64
           A +  +++     F +     +  +            V++HLA +  +PG     +L +D
Sbjct: 27  ASAQELLQWTEDTFGDGASAATGDRNGYIVASNMQDGVLVHLAAQV-HPG---VDVLFLD 82

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHK-----NPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           TG+ F E    RD   + YG  ++  +       + VA G + F     +   + K   L
Sbjct: 83  TGYHFPETIGTRDAVEQVYGVNVINARALASVAEQDVAEGKDLFARDPNRCCALRKVAPL 142

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           KQ L+  G+ A   G RR E  +RA   + SF + F                        
Sbjct: 143 KQTLS--GYSAWVTGIRRVEAPTRANAPLISFDEAFGL---------------------- 178

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
            +++ P++ W+++++  YI   +I + PL       +    G             P
Sbjct: 179 -VKINPIAPWSDEEMQNYIDTNSILVNPLVDEGYPSI----GCAPCTSKPAPGSDP 229


>UniRef50_C1AUL1 Phosphoadenosine phosphosulfate reductase n=11 Tax=Actinomycetales
           RepID=CYSH_RHOOB
          Length = 247

 Score =  152 bits (384), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 53/241 (21%), Positives = 90/241 (37%), Gaps = 50/241 (20%)

Query: 11  QLE-AESIHIIREVAAEFS----------NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
            LE A +  +++     F           N  ++ S  +D  V++HLA +  +PG     
Sbjct: 23  SLEGASARELLQWTEETFGSGASEGTGYRNSFIVASNMQDG-VLVHLAAQV-HPG---VD 77

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV-----AMGINPFVHGSAKHTDIM 114
           +L +DTG+ F E    RD   + YG  ++  +    V     A G + F     +   + 
Sbjct: 78  VLFLDTGYHFAETIGTRDAVEQVYGVNVINARAEASVAEQDAAEGKDLFAREPNRCCALR 137

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K   LK+ L   G+ A   G RR E  +RA   + SF D F                   
Sbjct: 138 KVAPLKKTLA--GYKAWVTGIRRVEAPTRANAPLISFDDAFGL----------------- 178

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                 +++ P++ W+++D+  YI   +I + PL       +    G             
Sbjct: 179 ------VKINPIAAWSDEDMQSYIDEHSILVNPLVDEGYPSI----GCAPCTSKPAPGSD 228

Query: 235 P 235
           P
Sbjct: 229 P 229


>UniRef50_B0C9W9 Phosphoadenosine phosphosulfate reductase n=1 Tax=Acaryochloris
           marina MBIC11017 RepID=B0C9W9_ACAM1
          Length = 242

 Score =  151 bits (381), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 43/215 (20%), Positives = 77/215 (35%), Gaps = 35/215 (16%)

Query: 14  AESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A    I+           +   + G    V++ L  K   P     P+L +DT   F E 
Sbjct: 25  AHPKSILTWCLENLPEGLIQSTAFGASGMVIMDLLYKDLNPN-PSIPVLFLDTLHHFPET 83

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVA--------MGINPFVHGSAKHTDIMKTEGLKQALN 124
            +  +     YG +L + + P+GV          G   +     +   + K E L++ L 
Sbjct: 84  LKLANDAQAHYGVDLQIFR-PQGVTSRAEFAQHYGEQLWETDLEQFHQLTKVEPLRRGLE 142

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           +        G RRD+  +RAK  I+                          ++   ++V 
Sbjct: 143 QLQVATWITGRRRDQSSTRAKMPIFE------------------------CDRDGRLKVN 178

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLER 219
           PL+NW+ +D+W Y+    +   PLY      + + 
Sbjct: 179 PLANWSYKDVWNYLVNNQVLYNPLYDQGYASIGDE 213


>UniRef50_D0LSJ1 Phosphoadenosine phosphosulfate reductase n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=D0LSJ1_HALO1
          Length = 285

 Score =  151 bits (381), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 61/281 (21%), Positives = 96/281 (34%), Gaps = 82/281 (29%)

Query: 11  QLE-AESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           +LE A    I+    A F     +  + G +   +LH+A +          +  +DTG+ 
Sbjct: 49  ELERATPQEILAFALASFAPRVAISTAFGVEGCALLHMAVQI----DPSVRVFTIDTGYL 104

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVA-----MGINPFVHGSAKHTDIMKTEGLKQAL 123
           F E  +  +R  +  G E+        VA      G   +   S     + K E  ++AL
Sbjct: 105 FDETQQLIERMRERLGIEIETFHPELSVAEQDERYGEALYTRDSDACCAMRKVEPTQRAL 164

Query: 124 NKYGFDAAFGGARRDEE-KSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
              G DA   G RRD+   +RA+  I            + QR +              I+
Sbjct: 165 R--GLDAWIAGLRRDQGGATRAQLAILE----------RYQRGDAEPL----------IK 202

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           V PL+NW   D W+Y+    +   PL                                  
Sbjct: 203 VHPLANWNRSDTWRYVLDNEVPYNPLLDQG------------------------------ 232

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
              ++++GCWP T AV ++A                ER GR
Sbjct: 233 ---YKSIGCWPCTRAVGADA---------------DERAGR 255


>UniRef50_D1CDF4 Phosphoadenosine phosphosulfate reductase n=2 Tax=Bacteria
           RepID=D1CDF4_THET1
          Length = 248

 Score =  151 bits (380), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 44/214 (20%), Positives = 80/214 (37%), Gaps = 37/214 (17%)

Query: 11  QLE-AESIHIIREVAAEFSN-PVMLYSIG-KDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +LE A    II+     F +  ++  S G      +L +A K          + ++DT +
Sbjct: 22  ELEDATPQEIIKWAVDRFGDGLILACSFGGISGMAILDMAVKI----KPDIDVFYIDTDF 77

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
            F E ++ ++   K YG + +  K       +    G   +         I K E  ++A
Sbjct: 78  LFPETHQTKEEAIKRYGIKPIAFKTKLTPEAQAEKYGDELWKRNPDLCCHIRKVEPTREA 137

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           L   G  A   G RRD+  +R   R   +  +F                          +
Sbjct: 138 LK--GRSAWITGLRRDQSSTRRNVRPVEWDYKFGL-----------------------YK 172

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
           + PL+ W E+++W+YI+  N+   PL+      +
Sbjct: 173 INPLAYWNEREVWRYIFKHNVPYNPLHDQGYPSI 206


>UniRef50_A4XB35 Phosphoadenylylsulfate reductase (Thioredoxin) n=3
           Tax=Actinomycetales RepID=A4XB35_SALTO
          Length = 256

 Score =  150 bits (379), Expect = 5e-35,   Method: Composition-based stats.
 Identities = 52/257 (20%), Positives = 94/257 (36%), Gaps = 69/257 (26%)

Query: 10  RQLE-AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           R+LE A ++ ++R     F +   + S   D +V++HL  +   PG     ++ +DTG  
Sbjct: 42  RELEGAPALEVVRWAVERFGDRFCVTSSMAD-AVLVHLVSRV-APG---VDVVFLDTGLH 96

Query: 69  FREMYEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           F E    RD+ ++     +   +       +    G   F         + K E L++AL
Sbjct: 97  FPETLRVRDQVSRTMPVNVRSIRPRLTVGQQDGEYGPRLFHRSPDDCCQLRKVESLERAL 156

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G+DA   G RRD+  SRA   + +F  R  +                       ++V
Sbjct: 157 --VGYDAWATGLRRDDSPSRANTPVVTFDTRRGK-----------------------VKV 191

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            P++ WT+ D+  YI   ++ +  L+                                  
Sbjct: 192 NPIAAWTQADVETYISQWDVPVNELF---------------------------------G 218

Query: 244 VRFRTLGCWPLTGAVES 260
             + ++GCWP T    +
Sbjct: 219 RAYSSVGCWPCTRRTRA 235


>UniRef50_A7MSZ6 Phosphoadenosine phosphosulfate reductase n=283 Tax=Bacteria
           RepID=CYSH_VIBHB
          Length = 259

 Score =  149 bits (376), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 47/218 (21%), Positives = 82/218 (37%), Gaps = 39/218 (17%)

Query: 9   LRQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           L QL A+    ++           +  S G  ++VMLHL  +         P++  DTG+
Sbjct: 33  LEQLSAQ--ERVKWALENLEGEFAVSSSFGIQAAVMLHLVTQQ----KPDIPIILTDTGY 86

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPF-------VHGSAKHTDIMKTEGLK 120
            F E Y+F D+        L V++  E        +       + G  K+  I K E ++
Sbjct: 87  LFAETYQFIDQLKAQLNLNLKVYRAKESANWQEARYGKLWEQGIEGIEKYNKINKVEPMR 146

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           +AL +      F G RR++ +SRA   I S ++                           
Sbjct: 147 RALREQNVGTWFSGLRREQSQSRAGLPILSIQN-------------------------GV 181

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE 218
            +  P+ +WT +D+  Y+    +   PL+      V +
Sbjct: 182 FKFLPVIDWTNKDVHYYLEEHGLSYHPLWEQGYLSVGD 219


>UniRef50_D1YYA8 Putative phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocella paludicola SANAE RepID=D1YYA8_METPS
          Length = 656

 Score =  149 bits (375), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 49/225 (21%), Positives = 85/225 (37%), Gaps = 40/225 (17%)

Query: 9   LRQLEAESIHIIREVAAEFSNP----VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           +  +E ++I++I+ V ++  N      + +S GKDS V+L+L +KA       F   ++D
Sbjct: 222 IEAMEKDAINVIKGVVSQGKNKELPVTVSFSGGKDSLVVLNLTKKAVK----KFEAFYID 277

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEGLKQ 121
           TG +F E  +F + TAK     + + K  +          P          + K   +  
Sbjct: 278 TGLEFPETTKFVEDTAKE--VPVKIEKAGKAFDENFPAFGPPAKDFRWCCKVCKLGPVTT 335

Query: 122 ALNKYGFDA-AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
            L+++        G RR E   R        R+ F                         
Sbjct: 336 HLSQFKKGVITIDGKRRYESFQRGGIDTVE-RNPF---------------------VPGQ 373

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           + VFP+ +W   ++W YI +E +    LY        ER G  + 
Sbjct: 374 MSVFPIKDWRAIEVWLYIHMEKLPYNELYDRG----FERIGCWLC 414


>UniRef50_D0N1L8 Phosphoadenosine phosphosulfate reductase n=2 Tax=cellular
           organisms RepID=D0N1L8_PHYIN
          Length = 382

 Score =  149 bits (375), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 48/234 (20%), Positives = 94/234 (40%), Gaps = 38/234 (16%)

Query: 13  EAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
           E  +  I++     F    V+  S G  S+VMLHL R      +   P++ VDTG+  +E
Sbjct: 54  EKTAQEIVQWTFDTFGARTVLSSSFGIQSAVMLHLTRSV----SKDIPVVWVDTGYLPKE 109

Query: 72  MYEFRDRTAKAYGCELLVHKNPEGVAMGINPF--------VHGSAKHTDIMKTEGLKQAL 123
            Y+F     K     + V+++P   A     +             ++  + K E +++AL
Sbjct: 110 TYQFAAHLTKLLDLNVRVYQSPITPARMEALYGKLYEIETPEAHRQYGYMRKVEPMQRAL 169

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           ++    A   G R D+ + R                   Q  +  + Y G+      +++
Sbjct: 170 DELNAAALLVGVRADQTQHR-------------------QHMKHVNVYEGR------LKI 204

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
            P+ NW++Q+I QY+    ++  PL       V +      + + ++ + + G 
Sbjct: 205 CPILNWSKQEIEQYMTANQLEYHPLKAQGYESVGDAHSSRPVTEADKGNDRAGR 258


>UniRef50_Q5HKZ5 Phosphoadenosine phosphosulfate reductase n=110 Tax=Bacillales
           RepID=CYSH_STAEQ
          Length = 243

 Score =  148 bits (373), Expect = 2e-34,   Method: Composition-based stats.
 Identities = 48/250 (19%), Positives = 86/250 (34%), Gaps = 69/250 (27%)

Query: 16  SIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           +  I++     + N  V   S G +S V++ L  +          ++ +DT   F+E Y+
Sbjct: 29  AYEILKWAYQTYENDIVYSCSFGAESMVLIDLISQI----KPDAQIVFLDTDLHFQETYD 84

Query: 75  FRDRTAKAY-GCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
             DR    Y    + + K       +G       + +   +   I K + L+  L+  G 
Sbjct: 85  LIDRVKDKYPQLRIKMKKPELTLEEQGEKYNPALWKNDPNQCCYIRKIKPLEDVLS--GA 142

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
            A   G RR +  +RA     +  +RF                       +SI+V PL  
Sbjct: 143 VAWISGLRRAQSPTRAHTNFINKDERF-----------------------KSIKVCPLIY 179

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           WTE+++W YI  +++    L+                                    + +
Sbjct: 180 WTEEEVWSYIRDKDLPYNELHDQ---------------------------------NYPS 206

Query: 249 LGCWPLTGAV 258
           +GC P T  V
Sbjct: 207 IGCIPCTSPV 216


>UniRef50_Q60377 Uncharacterized protein MJ0066 n=5 Tax=Methanocaldococcus
           RepID=Y066_METJA
          Length = 480

 Score =  146 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 46/232 (19%), Positives = 81/232 (34%), Gaps = 34/232 (14%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +   E  +I  I+    +   PVM+ +S GKDS V L L  KA         ++ +DTG 
Sbjct: 236 IDNYERNAIGFIKNTYEKIKKPVMVAFSGGKDSLVTLILTLKAL---GKDIDVVFIDTGL 292

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGLKQALNK 125
           +F E  +  +   + YG +++  +                     ++I K E LK+ + +
Sbjct: 293 EFEETLKNVEDVERHYGIKIIRLRGENFWEKVKEYGIPARDYRWCSEICKLEPLKKFIEE 352

Query: 126 YGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              D    F G R+ E  +RA ++                               + I  
Sbjct: 353 NYEDDVLSFVGIRKYESFNRATKKRIHRNTYIK----------------------KQINA 390

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
            P+ +W+   +W Y+  E      LY        +R G  M       ++  
Sbjct: 391 LPIFHWSSLHVWIYLLREKAPYNKLYEKG----FDRIGCFMCPAMEMGEMNK 438


>UniRef50_Q12UR6 Phosphoadenosine phosphosulfate reductase fused to RNA-binding PUA
           and 4Fe-4S binding domains n=3 Tax=Methanosarcinaceae
           RepID=Q12UR6_METBU
          Length = 633

 Score =  145 bits (366), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 50/231 (21%), Positives = 78/231 (33%), Gaps = 36/231 (15%)

Query: 9   LRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           L   E ++   I+  +   + PV + YS GKDS  +L L  +        + LL  DTG 
Sbjct: 228 LEHFEDKAHQFIKHTSKTVNRPVSVSYSGGKDSLAVLQLVSECL----DDYELLFADTGL 283

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEGLKQALN 124
           +F E  E      + Y   L      E     +    P    +     + K   + Q +N
Sbjct: 284 EFPETIENVKEIVEHYQRPLRTKDVGEAFWESVGDFGPPSVEARWCCKVCKLGPISQIIN 343

Query: 125 KYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
               D    F G R+ E  +RA                      +W N       G  I 
Sbjct: 344 DNYEDGCLTFIGQRKYESAARANSE------------------RVWKN----PWVGNQIG 381

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
             P+ +WT   +W YI+   +    +Y        +R G  +    +  DL
Sbjct: 382 ASPIQDWTAMHVWLYIFKTGVPYNVMYERG----FDRIGCWLCPSSSLSDL 428


>UniRef50_P56860 Phosphoadenosine phosphosulfate reductase n=4 Tax=Bacteria
           RepID=CYSH_DEIRA
          Length = 255

 Score =  145 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 53/251 (21%), Positives = 83/251 (33%), Gaps = 66/251 (26%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           E +   IIR   A   + +M  +   +  V+L LA +A Y G     ++ VDTG+ F E 
Sbjct: 40  ETDPRDIIRWALAAHPDLLMPSAFNLNGVVLLDLAAQAGYRGE----VVFVDTGYHFPET 95

Query: 73  YEFRDRTAKAYG----CELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
              RDR    Y       L    +P+      + +           K + L++ L + G 
Sbjct: 96  LATRDRLESRYPELTFVTLNAGASPDDGQTPPDLYASDPDACCAARKVDPLQRYLKEQGP 155

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
            A      RD+  +RA                                 G   RV PL++
Sbjct: 156 SALLNARSRDQASTRADIPFVE-------------------------EGGARRRVNPLAH 190

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           WT + +  Y    ++ + PLY                                    F +
Sbjct: 191 WTREQLEAYAAEHDLPVNPLYFDG---------------------------------FLS 217

Query: 249 LGCWPLTGAVE 259
           +GCWP T AV+
Sbjct: 218 IGCWPCTRAVK 228


>UniRef50_A2EL13 Putative uncharacterized protein n=2 Tax=Trichomonas vaginalis
           RepID=A2EL13_TRIVA
          Length = 215

 Score =  144 bits (362), Expect = 4e-33,   Method: Composition-based stats.
 Identities = 50/225 (22%), Positives = 89/225 (39%), Gaps = 45/225 (20%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           M  I     + L A+S  +I+E    +S+ +   Y+ GKDS V+L L             
Sbjct: 1   MSSINGLDAKILSAKS--VIKEAFERYSDKLSFCYNGGKDSVVLLDLVMNVVKENNYTIK 58

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
             +++ G +F E+ +F + + K +G +L+  K                      +K EGL
Sbjct: 59  PFYLEVGDEFDEILDFINYSEKYWGFKLMRIKA-------------------TNLK-EGL 98

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           ++ +N Y  ++ F G R D+  +  K + +   +                  NG     E
Sbjct: 99  EKLINTYQINSVFLGVRADDYPNI-KMKPFEPTN------------------NGW---PE 136

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLM 224
           + R+ P+ +WT  DIW+YI   N+    LY      +  +     
Sbjct: 137 AERIMPILDWTYNDIWEYIDKFNLPFCSLYNLGYTSIGPKSKTHP 181


>UniRef50_B9XLS6 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=1 Tax=bacterium
           Ellin514 RepID=B9XLS6_9BACT
          Length = 260

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 46/274 (16%), Positives = 82/274 (29%), Gaps = 78/274 (28%)

Query: 16  SIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           +  ++     +F     +  S      VM+HLA++      + FP+  +DTG  F E   
Sbjct: 36  TEEVLTWAWEKFGKRAAIGTSFQGAGLVMMHLAKQ----SGIQFPVFTLDTGLLFPETLA 91

Query: 75  FRDRTAKAYGCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
            + R    +G  +           +  A G   +         + K   L+  L     D
Sbjct: 92  LKKRLEDFFGFGIESLVPDLTLEQQAEAQGPELWKREPDLCCTMRKVLPLRSKLAD--LD 149

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
               G RR +  +R+   I                         +    + +++ P++NW
Sbjct: 150 CWITGLRRQQSDTRSSIGIIELYAFD------------------ETAGRDIVKLNPMANW 191

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
           + + +W YI    I   PL                                 +   +R++
Sbjct: 192 SREAVWNYIKEHKIPYNPL---------------------------------QDQGYRSI 218

Query: 250 GCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
           GC P T    S                 +ER GR
Sbjct: 219 GCQPCTNKTAS---------------GENERAGR 237


>UniRef50_D2L597 Phosphoadenosine phosphosulfate reductase n=1 Tax=Desulfovibrio sp.
           FW1012B RepID=D2L597_9DELT
          Length = 274

 Score =  142 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 66/324 (20%), Positives = 106/324 (32%), Gaps = 93/324 (28%)

Query: 9   LRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFP-LLHVDTG 66
           L +  A    ++      F     + ++  KDS+++L L R+A    +LP P +L +D G
Sbjct: 14  LEEKIAAGKAVVLAAIDRFGPDFWLAWTGAKDSTLVLWLTREACRERSLPMPRVLTIDEG 73

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPE----------------------------GVAM 98
             F E+  F++R  + +G +L V  N +                            G   
Sbjct: 74  DPFPEIQAFQERMVREWGLDLTVAANTDVLSRRPAIGDYLAVADLSPESRAEVARAGFTG 133

Query: 99  GINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRW 158
              PF   S     +MK   +   L      A     R DE  +RA E   S R+     
Sbjct: 134 EGFPFDPESPVGNQLMKVAPMNGFLRDNHVAALATAIRWDEHPARANEDYESPRED---- 189

Query: 159 DPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE 218
                                 +RV P+ +  E+D+W       I    LY         
Sbjct: 190 -------------------PPHLRVHPILHLRERDVWDITRSRGIPFCELYAKG------ 224

Query: 219 RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTS 278
                                      +R+LG    TG V      LP   +++    + 
Sbjct: 225 ---------------------------YRSLGTK--TGTVRQ--SDLPAWEQDLE-DRSG 252

Query: 279 ERQGRVIDRDQAGSMELKKRQGYF 302
           ER GR  D+++  +ME  +  GY 
Sbjct: 253 ERAGR--DQEKEEAMEQLRSLGYM 274


>UniRef50_A1KL82 Phosphoadenosine phosphosulfate reductase n=31 Tax=Actinomycetales
           RepID=CYSH_MYCBP
          Length = 254

 Score =  142 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 49/237 (20%), Positives = 80/237 (33%), Gaps = 68/237 (28%)

Query: 32  MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHK 91
           ++ S   D +V++ LA K         P++ +DTG+ F E    RD     Y   +L   
Sbjct: 62  VVASNMAD-AVLVDLAAKV----RPGVPVIFLDTGYHFVETIGTRDAIESVYDVRVLNVT 116

Query: 92  NPEGVAM-----GINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKE 146
               VA      G + F     +   + K   L + L   G+ A   G RR +  +RA  
Sbjct: 117 PEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLR--GYSAWVTGLRRVDAPTRANA 174

Query: 147 RIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIV 206
            + SF + F                         ++V PL+ WT+QD+ +YI   ++ + 
Sbjct: 175 PLVSFDETFKL-----------------------VKVNPLAAWTDQDVQEYIADNDVLVN 211

Query: 207 PLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQ 263
           PL                                     + ++GC P T      A 
Sbjct: 212 PL---------------------------------VREGYPSIGCAPCTAKPAEGAD 235


>UniRef50_A7NG75 Phosphoadenosine phosphosulfate reductase n=2 Tax=Chloroflexi
           (class) RepID=A7NG75_ROSCS
          Length = 238

 Score =  141 bits (355), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 45/268 (16%), Positives = 83/268 (30%), Gaps = 70/268 (26%)

Query: 10  RQLEAESIHIIREVAAE--FSNPVMLYSI-GKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            Q E +    +   AA        +  S  G    V+L +  +      L  P++ +DT 
Sbjct: 21  EQFETQPPEALLTWAAHMFCPRVALTCSFSGPSGMVLLDMVAR----LNLDIPVVFLDTD 76

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTEGLKQ 121
             F E YE      + YG  +   +       +    G   +     +   + K   L +
Sbjct: 77  LLFPETYELVAIAERRYGIPIRRRRPVLSVEEQDRQEGPQLYARDPDRCCQVRKVAPLAE 136

Query: 122 ALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
            L  Y  DA   G RRD+  +RA   +  +  R++                        +
Sbjct: 137 TLRTY--DAWISGIRRDQSDTRATIDLLEWNTRYNL-----------------------V 171

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
           ++ PL+ WT++ +W YI    +   PL                                 
Sbjct: 172 KISPLAFWTDRQVWAYIHHHQVPYNPL--------------------------------- 198

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEII 269
               + ++GC P T   +++       +
Sbjct: 199 LDRGYPSIGCLPCTRPADASDPRAGRWV 226


>UniRef50_A4WMI9 Phosphoadenosine phosphosulfate reductase n=5 Tax=Thermoproteaceae
           RepID=A4WMI9_PYRAR
          Length = 594

 Score =  141 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 52/237 (21%), Positives = 84/237 (35%), Gaps = 36/237 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           ++   H+ +   E++  I+ VA ++  PV++ YS GKDS V L L  +      L F + 
Sbjct: 203 ELNREHIERRAQEAVEFIKAVAEKYKKPVVVSYSGGKDSLVALDLTAR----SGLKFYVY 258

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEG 118
             DTG +  E YE      + YG E++V    +     +    P          ++K   
Sbjct: 259 FNDTGLEPPETYENLKAVEERYGVEVIVGAAGQRFWEAMEKFGPPARDYRWCCKVIKLGP 318

Query: 119 LKQALNKYGFDAAF--GGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
             +AL            G R  E   RAK    S                          
Sbjct: 319 TTEALKSRFPQGYISVVGQRGAESFVRAKTPRVSP----------------------SKW 356

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
              S+   PL  WT  ++W YI+L  +     Y        +R G ++   +   +L
Sbjct: 357 VAGSVVAAPLQEWTALEVWLYIFLHKLPYNRAYERG----FDRLGCVVCPANEMAEL 409


>UniRef50_Q2S5G4 Phosphoadenosine phosphosulfate reductase n=2 Tax=Bacteria
           RepID=CYSH_SALRD
          Length = 252

 Score =  141 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 48/279 (17%), Positives = 92/279 (32%), Gaps = 82/279 (29%)

Query: 19  IIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRD 77
           I+      F + +      G    V++H+      PGT    + ++DT   F E YE  D
Sbjct: 32  ILNWATHTFGDDLAQGTGFGPSGIVIMHMLA-DLRPGTT---VFYLDTDLLFPETYELCD 87

Query: 78  RTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAF 132
              +    ++           +    G   +     +   + K + L+  L+     A  
Sbjct: 88  DLDERLDVDVTRVHGGLSLDEQAEQEGEELWNRNPNRCCFLRKVKPLRNFLDDRR--AWI 145

Query: 133 GGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQ 192
            G RRD+ + RA   I S+  ++  +                       ++ PL+NWT++
Sbjct: 146 TGVRRDQSERRADTDILSWEGQYGVF-----------------------KINPLANWTQK 182

Query: 193 DIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCW 252
           ++W+Y++  ++   P +                                    + +LGC 
Sbjct: 183 EVWKYLFEHDLPYNPKHDQG---------------------------------YPSLGCV 209

Query: 253 PLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           P T  V+               +    R+GR  DRD+  
Sbjct: 210 PCTEPVDQ--------------ADGYSREGRWSDRDKTE 234


>UniRef50_C5QND2 Phosphoadenosine phosphosulfate reductase n=5 Tax=Bacillales
           RepID=C5QND2_STAEP
          Length = 244

 Score =  141 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 45/250 (18%), Positives = 82/250 (32%), Gaps = 69/250 (27%)

Query: 16  SIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           +  I+      +  + V   S G +S V++ L  +          ++ +DT   F+E Y+
Sbjct: 30  AYQILNWAYKTYGDDIVYSCSFGAESMVLIDLISQI----KPDAQIVFLDTDLHFQETYD 85

Query: 75  FRDRTAKAY-GCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
             DR    Y    + + K       +        + +   +   I K + L++ L   G 
Sbjct: 86  LIDRVRDKYPQLRIKMKKPELTLEEQAEKYNPALWKNNPNQCCYIRKIKPLEEVL--TGA 143

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
            A   G RR +  +RA     +  +RF                       +S++V PL  
Sbjct: 144 VAWVSGLRRAQSPTRASTDFINKDERF-----------------------KSVKVCPLIY 180

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           WTE ++W YI   ++    L+                                    + +
Sbjct: 181 WTEDEVWDYIKSNDLPYNELHDQH---------------------------------YPS 207

Query: 249 LGCWPLTGAV 258
           +GC P T  V
Sbjct: 208 IGCIPCTAPV 217


>UniRef50_Q7NK24 Phosphoadenosine phosphosulfate reductase n=6 Tax=Bacteria
           RepID=CYSH_GLOVI
          Length = 241

 Score =  139 bits (351), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 48/225 (21%), Positives = 82/225 (36%), Gaps = 38/225 (16%)

Query: 1   MDQIRLTHL-RQLEAESIH-IIREVAAEFSNPVMLYS-IGKDSSVMLHLARKAFYPGTLP 57
           +DQ  L HL RQ E  +   I+ E    F + ++L S  G +S ++L +  K +      
Sbjct: 12  IDQTTLEHLARQWEDLAPEAILAEAVRCFGDKLVLASAFGPESIILLDMLVKVW----PR 67

Query: 58  FPLLHVDTGWKFREMYEFRDRTAKAY-GCELLVH-----KNPEGVAMGINPFVHGSAKHT 111
                ++TG+ F E    +DR    +   +L V         +    G            
Sbjct: 68  PQAFFLETGFHFPETLALKDRVLARFPQLQLEVVGPLMSVAQQNAIYGERLHDRNPDHCC 127

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            I K E L +AL  Y   A   G RR++  +R +  +  +  R                 
Sbjct: 128 AIRKVEPLNRALAPYK--AWIAGMRREQSPTRGQIGVVQWDSRRG--------------- 170

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
                    ++  PL+ WT + +W YI   ++   PL+      +
Sbjct: 171 --------MVKFNPLATWTHKQVWAYIVERDLPYNPLHDEGFPSI 207


>UniRef50_B8ELQ2 Phosphoadenosine phosphosulfate reductase n=8
           Tax=Alphaproteobacteria RepID=B8ELQ2_METSB
          Length = 263

 Score =  139 bits (351), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 48/225 (21%), Positives = 80/225 (35%), Gaps = 44/225 (19%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL 87
               ++ S G DS+V+LH+  +         P+L +DTG  F E   +RD+  +  G   
Sbjct: 45  GKLALVSSFGADSAVLLHMIAEI----DRSLPVLFLDTGVLFPETLAYRDKLIERLGLTH 100

Query: 88  LVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKS 142
           +V   P     E        +     +  +I K   L +AL+  GFDA   G +R +  +
Sbjct: 101 VVTLVPDEATLESEDPETFLWSSHPDRCCEIRKVIPLARALD--GFDAWISGRKRFQAST 158

Query: 143 RAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN 202
           RA   ++   D                            ++ PL+NW+   I  Y+   +
Sbjct: 159 RAALPLFETED-------------------------NRTKINPLANWSPTQILNYLRAHD 193

Query: 203 IDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           +    L       +    G +      R    PGE  +    R R
Sbjct: 194 LPRHELVAKGYPSI----GCIPCTSKVR----PGEDPRAGRWRGR 230


>UniRef50_C5A452 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS
           reductase), containing one PUA domain and 2 4Fe-4S
           binding domains n=9 Tax=Thermococcaceae
           RepID=C5A452_THEGJ
          Length = 634

 Score =  139 bits (349), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 51/256 (19%), Positives = 90/256 (35%), Gaps = 41/256 (16%)

Query: 9   LRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           L +   +S   +R VA+++S     + +S GKDS  +L LA + F      F +   +TG
Sbjct: 232 LEEKVMKSREFMRRVASKYSDLPVAVAFSGGKDSLAVLGLALEEF---GSDFTVFFNNTG 288

Query: 67  WKFREMYEFRDRTAKAY---GCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEGLK 120
            +F E  E+  +  K     G + +V    +     +   +P          + K   + 
Sbjct: 289 IEFPETVEYVGKLRKELEPKGIKFVVADAGDAFWRALYVFSPPGRDYRWCCKVTKLGPIT 348

Query: 121 QALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
            A+ +        F G R+ E   R K                  +P +W N        
Sbjct: 349 LAIKENYPKGVLMFVGQRKYESIKRFK------------------QPRVWRNE----WVP 386

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR--IDLQPG 236
             I   P+ +W   ++W YI+   +   PLY        +R G  +    +    +    
Sbjct: 387 NEIGASPIFHWRAIEVWLYIFSRKLPYNPLYERG----FDRIGCFLCPSASLAEFERLKR 442

Query: 237 EVIKKRMVRFRTLGCW 252
           E  +     F+ L  W
Sbjct: 443 EKPELWEKWFKALEYW 458


>UniRef50_Q1GFS4 Phosphoadenylylsulfate reductase (Thioredoxin) n=17
           Tax=Rhodobacterales RepID=Q1GFS4_SILST
          Length = 253

 Score =  137 bits (346), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 44/261 (16%), Positives = 85/261 (32%), Gaps = 65/261 (24%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +Q+   + R     +  ++     +  N  ++ S G +S V+LH+A           P+L
Sbjct: 23  EQVAALNARFKHHSATSVMEGALRDAGNIALVSSFGAESVVLLHMAAVI----DPSVPVL 78

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFV---HGSAKHTDIMKTEG 118
            VDT   F E   ++   ++  G   +     + +A            +     + KT  
Sbjct: 79  FVDTELLFTETLVYQQEVSERLGLRNVHVIKADDIAEKDPYGAMRFSDTDACCTLRKTIP 138

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L++AL   G+D    G +R +  +RA    +   D   R                     
Sbjct: 139 LQKALA--GYDGWITGRKRFQSGTRAALDFFEVEDGTGR--------------------- 175

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +++ PL++W  +D+  Y+    +   PL                              
Sbjct: 176 --MKINPLAHWAPEDVRAYMDENRLPRHPLVAKG-------------------------- 207

Query: 239 IKKRMVRFRTLGCWPLTGAVE 259
                  + ++GC P T  V 
Sbjct: 208 -------YPSIGCEPCTSPVA 221


>UniRef50_Q164V6 Phosophoadenylyl-sulfate reductase n=24 Tax=Rhodobacterales
           RepID=Q164V6_ROSDO
          Length = 253

 Score =  137 bits (345), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 50/268 (18%), Positives = 87/268 (32%), Gaps = 74/268 (27%)

Query: 5   RLTHLRQLEAE---------SIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGT 55
           R   L+ L  E         ++ +++   AE +   ++ S G +S  +LHLA        
Sbjct: 15  RTDELQALVQELNTRLRHHGAVDVLQVALAEITPLSLVSSFGAESVALLHLASMVDRN-- 72

Query: 56  LPFPLLHVDTGWKFREMYEFRDRTAKAYGC-ELLVHKNPE--GVAMGINPFVHGSAKHTD 112
              P++ VDT   F +   ++   A+  G   L + ++ +            H       
Sbjct: 73  --IPVIFVDTEMLFTQTLVYQQELAERLGLRNLRIVRSGDIAHRDPTGTMHRHDPDGCCA 130

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           + KTE L++AL   G +    G +R +   RA    +    +  R               
Sbjct: 131 LRKTEPLQKAL--VGSNGWITGRKRYQSGQRAALEHFEIEAQTGR--------------- 173

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
                   I+V PL+ W   D+  YI    +   PL                        
Sbjct: 174 --------IKVNPLAYWQAGDVADYITENRLPRHPLVAQG-------------------- 205

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAVES 260
                        + ++GC P T  V+S
Sbjct: 206 -------------YPSIGCAPCTSPVQS 220


>UniRef50_B1VHQ3 Adenosine phosphosulfate reductase n=17 Tax=Corynebacterium
           RepID=B1VHQ3_CORU7
          Length = 283

 Score =  136 bits (342), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 40/224 (17%), Positives = 80/224 (35%), Gaps = 32/224 (14%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A +  I+   A +   PV +    +D +++  LA++AF        L+ +DTG+ F E  
Sbjct: 71  ASAAEILSWAAEQLDGPVAITLSMQD-TILAELAQRAFDGQQADAELVFLDTGYHFPETL 129

Query: 74  EFRDRTAKAYGCEL-----LVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
           +      + Y   L      + +  +    G N +         + K E L + L+   F
Sbjct: 130 DTAAAVEERYNLPLRRITPTLSRAEQDDVYGPNLYQRNPTACCRMRKVEPLARMLDP--F 187

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
           +A   G RR +   RA   +                            +   +++ P++ 
Sbjct: 188 EAWVSGVRRVDSPLRANTPVIEVD------------------------RTGRLKLNPIAA 223

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
           WT+ D+ ++I   ++ I PL       +      L + +     
Sbjct: 224 WTDDDVQRFIEDNDLIINPLTKQGYPSIGCATCTLPVAEGEDPR 267


>UniRef50_Q8DK35 Phosphoadenosine phosphosulfate reductase n=9 Tax=Cyanobacteria
           RepID=Q8DK35_THEEB
          Length = 246

 Score =  136 bits (342), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 49/267 (18%), Positives = 81/267 (30%), Gaps = 48/267 (17%)

Query: 1   MDQIRLTHLRQLE-----AESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPG 54
           M       L  L      A    I+     E     V   +   D  V+  L  +   P 
Sbjct: 11  MAASVSFDLDALNQRFEGAHPRDILAWAVTEIPQGLVQTSAFNVDDMVITDLLYRDLRPN 70

Query: 55  TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE-------GVAMGINPFVHGS 107
             P P+L +DT   F E   F  +  + Y  +L  +K P+           G   +    
Sbjct: 71  -PPVPVLFLDTLHHFAETLAFVQQAKEKYSLDLRTYKIPDVDSREAFAARYGDKLWETNV 129

Query: 108 AKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPEL 167
            +   + K E L++ L +    A   G RRD+  +RA                       
Sbjct: 130 EQFHHLTKIEPLQRGLAELHTVAWITGRRRDQALTRANMPYVELDKE------------- 176

Query: 168 WHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
                        +++ PL+ WT +  W Y+    +   PL+      +           
Sbjct: 177 -----------GRLKINPLAAWTRKQTWAYVMEHGVIYNPLHDRGYASI----------G 215

Query: 228 DNRIDLQPGEVIKKRMVRFRTLGCWPL 254
           D  +     E   +R  R+R +G    
Sbjct: 216 DEPLTTPIAEGEDERAGRWRGMGKTEC 242


>UniRef50_B0T3S8 Phosphoadenosine phosphosulfate reductase n=7
           Tax=Alphaproteobacteria RepID=B0T3S8_CAUSK
          Length = 258

 Score =  136 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 53/284 (18%), Positives = 93/284 (32%), Gaps = 84/284 (29%)

Query: 14  AESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A  + ++R+    F +   ++ S G +S+V+LHLA +     +   P+L +DTG  F + 
Sbjct: 34  AHPLTVLRKAYETFGDKLALVSSFGAESAVLLHLASQV----SKDIPVLFLDTGMLFGQT 89

Query: 73  YEFRDRTAKAYGC----ELLVHKNPEGV-AMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
            ++R   A   G     +L        V     + +   +     I K   L +AL +  
Sbjct: 90  LDYRKSLAAKLGLTDVRDLRPAYTDLAVTDPKSDLWRTDTDACCHIRKVLPLDRALGE-- 147

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           F A   G +R     R + R+                                I+  PL+
Sbjct: 148 FAAWTTGRKRFHGGDRLRLRVVE-------------------------ETQGQIKFNPLA 182

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           NW + ++  Y+   ++   PL                                     F 
Sbjct: 183 NWGKAELDAYVAEYDLPAHPL---------------------------------VSQGFP 209

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           ++GCWP T  V+  A  +              R GR   +D+  
Sbjct: 210 SVGCWPCTKPVDDPAADV--------------RAGRWAGQDKTE 239


>UniRef50_B5IFS1 Phosphoadenosine phosphosulfate reductase n=2 Tax=Aciduliprofundum
           boonei T469 RepID=B5IFS1_9EURY
          Length = 580

 Score =  136 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 45/238 (18%), Positives = 79/238 (33%), Gaps = 36/238 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +  + HL  +E  ++  IRE    +  P  + +S GKDS  +L LA K      + F   
Sbjct: 215 EANIQHLENIENRAVKFIRETKMRYDLPLAVSFSGGKDSLAVLLLALK----SGMDFHTF 270

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEG 118
            ++TG +  E  E+ +   K YG ++            +    P          + K   
Sbjct: 271 FLNTGIELPETVEYVNEIEKKYGIKMDRIDAGNAFWGSLEHFGPPGRDYRWCCKVTKLGP 330

Query: 119 LKQALNKYGFDAAFG--GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
             + + +          G RR E   R +                  +  +W N      
Sbjct: 331 TTKYILENYPSGLLTLIGQRRYESMERMR------------------KGNIWRN----EW 368

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
               +   P+ NW+  ++W YI  +   I   Y       L R G  +    +  D +
Sbjct: 369 VPNQLSASPIQNWSSLEVWLYILWKRAPINVWYKRG----LTRIGCYLCPSSDLADFE 422


>UniRef50_Q2FND9 Phosphoadenosine phosphosulfate reductase n=7
           Tax=Methanomicrobiales RepID=Q2FND9_METHJ
          Length = 885

 Score =  136 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 50/219 (22%), Positives = 80/219 (36%), Gaps = 36/219 (16%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           HL+ LE  ++  I+    +     + +S GKDS+ +LHLARKA            +DTG 
Sbjct: 201 HLKNLERNAVRTIKSHMKDRPTVNVSFSGGKDSTAVLHLARKAGVE-----KAFFIDTGL 255

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPE-GVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           +F E   F +      G E++              P    +     ++K   LK  L   
Sbjct: 256 EFPETIRFIEEQ----GVEIIRKGGDFWQAVEKAGPPGKDNRWCCKLLKLHPLKIYLADT 311

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           G      G R  E  +RA              D  +Q P               + + P+
Sbjct: 312 GPCVTIQGNRWYESWNRAGL------------DETSQNP----------ANPLQLNISPI 349

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
            +W   +++ Y+W   I + PLY       +ER G  + 
Sbjct: 350 RSWRAFEVFLYLWWRKIPLNPLYERG----IERIGCYLC 384


>UniRef50_Q12WD1 Phosphoadenosine phosphosulfate reductase n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12WD1_METBU
          Length = 667

 Score =  133 bits (335), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 47/237 (19%), Positives = 79/237 (33%), Gaps = 39/237 (16%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS----NPVMLYSIGKDSSVMLHLARKAFYPGTLPF 58
              L HLR++   +++ I+ +A++         + +S GKDS V+L L   A        
Sbjct: 237 TANLPHLRKIGKNAMNTIKGIASQKEHRKLPVHVSFSGGKDSLVVLDLTLSALK--GRDV 294

Query: 59  PLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMK 115
               ++TG +F E  EF     +  G EL+  K        +    P          + K
Sbjct: 295 RAFFLNTGIEFPETVEFVHSHCENRGIELIESKAENAFWENLESFGPPAKDFRWCCKVCK 354

Query: 116 TEG----LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
                  + Q     G      G R+ E  SR+                           
Sbjct: 355 LGPAGAIIDQCSENGGVCLTIDGKRKFESFSRSN----------------------ISAS 392

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
                    + +FP+ +W   ++W YI+   +D  PLY        ER G  +   +
Sbjct: 393 EKNPFVPNQLNIFPIRDWRAIEVWLYIYWRKLDYNPLYDVG----FERVGCYLCPAE 445


>UniRef50_A7HWV2 Phosphoadenosine phosphosulfate reductase n=1 Tax=Parvibaculum
           lavamentivorans DS-1 RepID=A7HWV2_PARL1
          Length = 252

 Score =  133 bits (335), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 50/267 (18%), Positives = 85/267 (31%), Gaps = 72/267 (26%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL 87
               ++ S G +S+V+LH+  +         P++ ++TG  F E   FRDR  +  G   
Sbjct: 37  GKIAVVSSFGAESAVLLHMVAQV----DPTTPVIFLNTGKLFGETLRFRDRLQEKLGLTD 92

Query: 88  LVHKNPE-----GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKS 142
           +    P              +         + K   L++AL   GFDA+  G +R +  +
Sbjct: 93  IRAVGPHPADLAAKDPNGGLWNADPDACCYVRKVLPLERALA--GFDASITGRKRFQTNA 150

Query: 143 RAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN 202
           RA               P +             + G   ++ PLS W + D+ +Y+    
Sbjct: 151 RAGMDPIEEEKIRGTGVPGS-------------DAGTRFKINPLSYWGQDDLERYMDEYK 197

Query: 203 IDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNA 262
           +   PL                                     + ++GC P T  V    
Sbjct: 198 LPRHPL---------------------------------VKDNYLSIGCMPCTERVP--- 221

Query: 263 QTLPEIIEEMLVSTTSERQGRVIDRDQ 289
                          S R GR + RD+
Sbjct: 222 ------------EGGSYRDGRWVGRDK 236


>UniRef50_C1SHC5 PAPS reductase/FAD synthetase family protein n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SHC5_9BACT
          Length = 764

 Score =  133 bits (335), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 50/227 (22%), Positives = 88/227 (38%), Gaps = 39/227 (17%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV----MLYSIGKDSSVMLHLARKAFYPGTL 56
           M +     L  +E  ++  I  V  ++ + +    + +S GKDS+V+L L +KA   G+ 
Sbjct: 110 MVESNREMLDIIEQSTVKKIISVYTKYKDKLDLFHVAFSGGKDSAVLLDLVKKALPLGS- 168

Query: 57  PFPLLHVDTGWKFREMYEFRDR---TAKAYGCELLVHKN---PEGVAMGINPFVHGSAKH 110
            F ++  DTG +F + Y+  D+     +A G    + K+   P+   +   P        
Sbjct: 169 -FVVVFGDTGMEFPDTYDVIDKTRQMCEADGIPFYIAKSSLEPQESWVLFGPPSRALRWC 227

Query: 111 TDIMKTEG----LKQALNKYGFDA-AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRP 165
             + K+      L+    K  +   AF G R +E   RA        +  +    K QR 
Sbjct: 228 CGVHKSAPQTLKLRAVTGKNDYTGLAFVGVRSEESAKRA--------EYDYENYSKKQRG 279

Query: 166 ELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAA 212
           +  H                +  WT  ++W Y++  NI I   Y   
Sbjct: 280 QYSH--------------NSILEWTSAEVWLYLYANNIMINEAYKKG 312


>UniRef50_C4XSH1 Putative adenylyltransferase n=1 Tax=Desulfovibrio magneticus RS-1
           RepID=C4XSH1_DESMR
          Length = 270

 Score =  133 bits (335), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 61/324 (18%), Positives = 100/324 (30%), Gaps = 93/324 (28%)

Query: 9   LRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFP-LLHVDTG 66
           L    A S  ++      F +   + ++  KDS++ L LAR+         P +L +D G
Sbjct: 10  LDDKIALSKRVLAGAMDRFGHTFWIAWTGAKDSTLTLWLARELCRETGRTMPRVLTIDEG 69

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKN------------------------PEGVAMGIN- 101
             F E+ +F+ R    +G ++ +  N                         E    G   
Sbjct: 70  DPFPEILDFQKRLTADWGLDVHLAANHEILDRKPAIGDYIDLSGLSQAVRDEAARTGFTG 129

Query: 102 ---PFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRW 158
              PF   S     +MK   +   L + G  A     R DE  +R  E   S R+     
Sbjct: 130 PGFPFDPESPLGNQLMKVLPMNTFLRENGVAALATAIRWDEHPAREGELYESPREE---- 185

Query: 159 DPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE 218
                                 +RV P+ +  E D+W       +    LY         
Sbjct: 186 -------------------PPHLRVHPILHMREADVWAITRGRGLPHCSLYAKG------ 220

Query: 219 RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTS 278
                                      +R+LG    T +       LP   +++    + 
Sbjct: 221 ---------------------------YRSLG----TLSGTVRKSDLPAWEQDLD-DRSG 248

Query: 279 ERQGRVIDRDQAGSMELKKRQGYF 302
           ER GR  D++   +ME  +  GY 
Sbjct: 249 ERAGRDQDKED--AMEQLRALGYM 270


>UniRef50_Q4J7K3 Phosphoadenosine phosphosulfate reductase n=1 Tax=Sulfolobus
           acidocaldarius RepID=Q4J7K3_SULAC
          Length = 211

 Score =  133 bits (334), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 54/274 (19%), Positives = 82/274 (29%), Gaps = 90/274 (32%)

Query: 55  TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE-------------------- 94
                 + +D    F E +EF +R  K +G  ++V  N                      
Sbjct: 2   NKEVKAIVIDHFMHFDETWEFIERVKKEWGVSVVVKGNERLKGHKYGDVVKVSELSREDR 61

Query: 95  ------GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERI 148
                 G       F   +     ++KT  LK+A+     DA   G R DE  +RA E  
Sbjct: 62  EELQRLGYNREEFVFALNNIAGNHLLKTVPLKEAVKDLKIDALIVGVRWDENPARASETF 121

Query: 149 YSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPL 208
           +S R+                            RV  +  +TE+DIW++     + + PL
Sbjct: 122 FSPRED-----------------------PPHTRVHTILLFTERDIWEFTLGNRLPVHPL 158

Query: 209 YLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEI 268
           Y                                    +R+L     T  V          
Sbjct: 159 YYKG---------------------------------YRSLDDKYETKKVSDKPA----- 180

Query: 269 IEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
             E  +  T ER GR  D+     ME+ +R GY 
Sbjct: 181 -WEQNLENTPERVGRAQDKGNI--MEILRRHGYM 211


>UniRef50_C6P7J4 Adenylylsulfate reductase, thioredoxin dependent n=1
           Tax=Sideroxydans lithotrophicus ES-1 RepID=C6P7J4_9PROT
          Length = 265

 Score =  133 bits (334), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 50/259 (19%), Positives = 84/259 (32%), Gaps = 74/259 (28%)

Query: 11  QLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFR 70
           ++EA +I ++ + A EF+  V   S+G +  V+  L  K          +  +DTG   +
Sbjct: 8   KIEA-TIAVLHQAANEFAPVVFASSLGAEDMVLTDLIAK----HRPDIQMFSLDTGRLPK 62

Query: 71  EMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAK----------HTDIMKTEGLK 120
           E Y+        Y   L ++  P+G  +      HG                + K E L+
Sbjct: 63  ETYDLMQEVRLRYSVPLTIYF-PDGKLVEDYVAQHGINGFYDSVENRKGCCFVRKVEPLR 121

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           +AL   G  A   G RRD+  +R    + +F                             
Sbjct: 122 RALA--GKGAWITGMRRDQAVTRGTLAVSAFDVDNGLQ---------------------- 157

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
            +  PL  W+  D+W YI   ++    L+                               
Sbjct: 158 -KFNPLLEWSHNDVWTYIRQHDVPYNKLHDQF---------------------------- 188

Query: 241 KRMVRFRTLGCWPLTGAVE 259
                + +LGC P T +V 
Sbjct: 189 -----YPSLGCAPCTRSVT 202


>UniRef50_C1XVG3 Phosphoadenylylsulfate reductase (Thioredoxin) n=3 Tax=Deinococci
           RepID=C1XVG3_9DEIN
          Length = 222

 Score =  132 bits (332), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 51/249 (20%), Positives = 84/249 (33%), Gaps = 65/249 (26%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           E +   +IR    E+ + +M  +   +  V++ LA +A Y G     ++ VDTG+ F E 
Sbjct: 10  ETDPRVVIRWAMEEYPDSLMTSAFNLNGVVLIDLAAQAGYTGE----VVFVDTGYHFPET 65

Query: 73  YEFRDRTAKAYG-CELLVHKNPEGVAM-GINPFVHGSAKHTDIMKTEGLKQALNKYGFDA 130
            + R+R A  Y     +           G   +           K   L++ L +    A
Sbjct: 66  LQTRERLAARYSQMRFVTLSAGLAPEPWGEERYRSDPDGCCAARKVAPLREYLARKNPSA 125

Query: 131 AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWT 190
                 RD+  +RA                            G +  GE +RV PL+ WT
Sbjct: 126 LLNARSRDQAATRAGL--------------------------GFLEPGERLRVNPLAYWT 159

Query: 191 EQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLG 250
            + +  Y    ++ + PLY +                                  F ++G
Sbjct: 160 REQLEAYARTRDLPVNPLYWSG---------------------------------FLSIG 186

Query: 251 CWPLTGAVE 259
           CWP T AV 
Sbjct: 187 CWPCTRAVR 195


>UniRef50_A2BKK3 Phosphoadenosine 5'-phosphosulfate reductase n=1 Tax=Hyperthermus
           butylicus DSM 5456 RepID=A2BKK3_HYPBU
          Length = 660

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 50/233 (21%), Positives = 75/233 (32%), Gaps = 35/233 (15%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
             L +LE E++  +        + ++  S GKDS+V   LA KA             DTG
Sbjct: 223 ERLERLEREAVEFLENRVKGLGDVMVAVSGGKDSTVAAALAVKAGLR-----RAYFFDTG 277

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEGLKQAL 123
            +F E  E   R A+  G ++            +    P          ++K   L +AL
Sbjct: 278 IEFPETIETAHRVAQTLGLDMAEISAGNTFWRALRLFGPPARDYRWCCKVVKFAPLAKAL 337

Query: 124 NKYGFD--AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
                       G R  E   RA     S      R D                     +
Sbjct: 338 KPLVKTRLVTVTGQRGYESTQRAMAGKLSPSATTGRRD---------------------L 376

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
              P+  WT  D++ YIW E + + PLY        ER G  +       ++ 
Sbjct: 377 LAAPIQEWTSLDVYAYIWREKLPLNPLYEMGY----ERVGCYLCPTSRLAEID 425


>UniRef50_UPI000169461E phosphoadenosine phosphosulfate reductase n=1 Tax=Paenibacillus
           larvae subsp. larvae BRL-230010 RepID=UPI000169461E
          Length = 179

 Score =  131 bits (328), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 36/166 (21%), Positives = 62/166 (37%), Gaps = 30/166 (18%)

Query: 56  LPFPLLHVDTGWKFREMYEFRDRTAKAYGCELL-----VHKNPEGVAMGINPFVHGSAKH 110
               + ++DT   F+E Y  +DR  + Y  E +     +    +    G   +       
Sbjct: 4   PSIDIFYLDTHVHFKETYLTKDRLQEKYNIEFIQVEPKISLAEQADRFGEELWKSDPNSC 63

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
            +I K E L + L++Y  DA   G RRD+  +RA     ++  +F               
Sbjct: 64  CNIRKVEPLSRILSEY--DAWITGIRRDQAPTRANAPKAAYDTKF--------------- 106

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
                   +  +  PL+NWT  D+W YI    +   PL+      +
Sbjct: 107 --------DLAKFNPLANWTSDDVWDYIREYELIYNPLHDQNYPSI 144


>UniRef50_A8AAE7 Phosphoadenosine phosphosulfate reductase n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8AAE7_IGNH4
          Length = 648

 Score =  130 bits (327), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 49/226 (21%), Positives = 82/226 (36%), Gaps = 39/226 (17%)

Query: 8   HLRQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            LR+L ++S   I  + ++   P  + +S GKDS V LHL  +   P      ++  +TG
Sbjct: 209 RLRRLTSQSKRFIYSMVSKVEKPLTVSFSGGKDSLVALHLTLEFGKPI-----VVFNNTG 263

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAM---GINPFVHGSAKHTDIMKTEGLKQAL 123
            +  E  E   R  +A+  EL V              +P          + K   + + +
Sbjct: 264 IEMPETVETVRRVVEAFDLELAVADAGNSFWEAMKRNSPPARDLRWCCKVTKLVPMAKLV 323

Query: 124 NKYGFDAAF--GGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
            +          G R  E   R+K                   P +W N        + +
Sbjct: 324 KERWPSGTLNVVGQRAFESIERSK------------------SPRVWRN----KWFPQVL 361

Query: 182 RVFPLSNWTEQDIWQYIWLENI--DIVPLYLAAERPVLERDGMLMM 225
            + P+  WT+ D+W YI+ + +   + PLY        ER G  M 
Sbjct: 362 NIAPIHYWTQLDVWMYIFQKGLKDLVNPLYFKG----FERIGCFMC 403


>UniRef50_Q2FU39 Uncharacterized domain 2 n=2 Tax=Methanomicrobiales
           RepID=Q2FU39_METHJ
          Length = 466

 Score =  130 bits (326), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 55/242 (22%), Positives = 85/242 (35%), Gaps = 39/242 (16%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           Q     L+++EA S   I +    +      + YS GKDS   L +    +       P+
Sbjct: 212 QANADVLKKVEAASGKFIADSIGPYEHLPMSVSYSGGKDSLATLLVVMNTYR----KMPI 267

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTE 117
           L++DTG +F    E        YG E +  ++            P    +       K E
Sbjct: 268 LYIDTGLEFPSTEENVCDVQDRYGLECVRIESINEFWRDFEVSGPPSRDNRWCCRTSKLE 327

Query: 118 GLKQAL-NKYGFDA---AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
            L+Q +   YG D    +F G R+ E  SR K                   P +W N   
Sbjct: 328 PLRQYIVKTYGEDGEIVSFIGQRKYESFSRMK------------------NPRVWRN--- 366

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
                  I + P+  WT   +W YI+ E      +Y    R  ++R G  M    +   L
Sbjct: 367 -SYVNNQICLAPIHTWTALHVWLYIFREKAPFNEMY----RHGVDRMGCYMCPASDLGVL 421

Query: 234 QP 235
           + 
Sbjct: 422 EK 423


>UniRef50_D1I5Z9 Whole genome shotgun sequence of line PN40024,
           scaffold_59.assembly12x (Fragment) n=20 Tax=cellular
           organisms RepID=D1I5Z9_VITVI
          Length = 467

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 55/284 (19%), Positives = 92/284 (32%), Gaps = 78/284 (27%)

Query: 9   LRQLEAES-IHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
            + LE+ S + I+ +    F N + +   G +  V++  AR        PF +  +DTG 
Sbjct: 92  AKDLESASPLEIMDKALQNFGNDIAIAFSGAEDVVLIEYAR----LTGRPFRVFSLDTGR 147

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV---HGSAKHTDIMKTEGLK 120
              E Y F D   K YG  +          + +      F     G  +   I K   L+
Sbjct: 148 LNPETYAFFDTVEKHYGIHIEYVFPDSVEVQALVRNKGLFSFYEDGHQECCRIRKVRPLR 207

Query: 121 QALNKYGFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           +AL   G  A   G R+D+   +RA+  +      F   D                  G 
Sbjct: 208 KALK--GLRAWITGQRKDQSPGTRAEIPVVQVDPTFEGMDSG---------------VGS 250

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
            ++  P++N    DIW ++   N+ +  L+                              
Sbjct: 251 LVKWNPVANVDSMDIWNFLRAMNVPVNSLHSQG--------------------------- 283

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                 + ++GC P T  V               +    ER+GR
Sbjct: 284 ------YVSIGCEPCTRPV---------------LPGQHEREGR 306


>UniRef50_A1VQ08 Phosphoadenylylsulfate reductase (Thioredoxin) n=7
           Tax=Proteobacteria RepID=A1VQ08_POLNA
          Length = 264

 Score =  129 bits (323), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 54/255 (21%), Positives = 82/255 (32%), Gaps = 70/255 (27%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A S+ +I+  A E+S      S+G +  V+ HL  +A         +  +DTG    E  
Sbjct: 19  AHSLALIKTAATEYSPLTQASSLGCEDMVITHLMHEAGLDNA-SASIFVLDTGMLHLETV 77

Query: 74  EFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSA---------KHTDIMKTEGLKQALN 124
               R  + Y  ++ V+      A          A         +   I K E L++AL 
Sbjct: 78  ALIGRIEERYPFKVDVYHPDADAASAFVEENGSQAMYKSLALRKQCCHIRKMEPLERALA 137

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             G      G RR++  +RA+                               + E  ++ 
Sbjct: 138 --GKKGWLTGLRREQSAARAEVHDIE-------------------------QQPERAKIN 170

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL  WT+ DIW YI L  I   PL+                                   
Sbjct: 171 PLVEWTQGDIWHYIALNEIPYNPLHDQF-------------------------------- 198

Query: 245 RFRTLGCWPLTGAVE 259
            F ++GC P T AV 
Sbjct: 199 -FPSIGCAPCTRAVT 212


>UniRef50_A3DN95 Phosphoadenosine phosphosulfate reductase n=2
           Tax=Desulfurococcaceae RepID=A3DN95_STAMF
          Length = 656

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 48/230 (20%), Positives = 78/230 (33%), Gaps = 36/230 (15%)

Query: 15  ESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           ++I  +R++  +   PV++ YS GKDS   L+L  +A         LL  DTG +  E  
Sbjct: 212 KAIKFLRKLYEKNKLPVVVSYSGGKDSLTALNLTLEALGDAE----LLFNDTGLELPETI 267

Query: 74  EFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEGLKQALN-KYGFD 129
           +  +  +K YG +L+     +     +    P          I K   + +    K+G  
Sbjct: 268 KNVEYVSKHYGLKLVKASAGDAFWKAVWIFGPPGKDYRWCCKITKLVPIARVTKAKWGNG 327

Query: 130 AA-FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
           A    G R  E   RA+                   P +W N          +   P+  
Sbjct: 328 ALNIVGQRAYESIDRAR------------------SPSVWRNR----WVPHLLSASPIQE 365

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
           W +   W YI    +    LY        ER G  +       + +  E 
Sbjct: 366 WNQLVEWLYITKYKLPYNKLYDMG----FERLGCYVCPSSTLAEFKEIEK 411


>UniRef50_A2BN02 Phosphoadenosine phosphosulfate reductase n=1 Tax=Hyperthermus
           butylicus DSM 5456 RepID=A2BN02_HYPBU
          Length = 451

 Score =  127 bits (319), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 47/229 (20%), Positives = 79/229 (34%), Gaps = 35/229 (15%)

Query: 12  LEAESIHIIREVAAEF----SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           L +E+   IR V A +        + +S G DS+ +L LAR+A  P  +    ++VDTG 
Sbjct: 204 LASEAREFIRRVYARYQASRGRLYVAFSGGSDSATVLSLAREAVGPENVV--AVYVDTGM 261

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVA---MGINPFVHGSAKHTDIMKTEGLKQALN 124
           +F E   + ++     G +L V +                      T ++K + L++   
Sbjct: 262 EFPETRRYVEKVTSILGVDLEVVEAEAEPIEEIRRRGLMTRDDRWCTRLLKLKPLRRFYR 321

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             G      GARR E  +RA                                    +R  
Sbjct: 322 SRGVRLILDGARRWESTTRASTPRIG----------------------ENPLIPGVVRAL 359

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
           P+ +W    +  Y++   I    LY       L R G +     +  +L
Sbjct: 360 PIHHWPRLAVQLYLYERGIPFNHLYSKG----LTRIGCISCPAMHLYEL 404


>UniRef50_A9KBQ9 Phosphoadenosine phosphosulfate reductase n=3 Tax=Coxiella burnetii
           RepID=A9KBQ9_COXBN
          Length = 218

 Score =  127 bits (318), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 43/226 (19%), Positives = 79/226 (34%), Gaps = 43/226 (19%)

Query: 14  AESIHIIREVAAEFSNP--VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV--DTGWKF 69
            ++  +IR+   EF N    +L S GKDS V+LHL R+          +  +  DT  +F
Sbjct: 11  KQAKALIRDTLNEFENKRVGLLCSFGKDSMVLLHLCREI----DPNIKVYSLVSDT--EF 64

Query: 70  REMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
            E Y++     + +      +             +       +  K   ++  L +   D
Sbjct: 65  DETYQYIRFIVETWNLNYHQY------DFMQKDLIDSPGNCCNGRKVSAMQSVLAE--LD 116

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
               G R DE   R                          N+  +      +++ P+  +
Sbjct: 117 CWIAGVRGDEGTER-------------------------KNFAQREQVSNLVKINPILAF 151

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
           +E DIW+Y+ + NI + PLY    R +  R         ++ +   
Sbjct: 152 SEADIWRYLAINNISVHPLYSKGYRSLGCRLCSTPERGSDQSERDG 197


>UniRef50_B4WAM0 Phosophoadenylyl-sulfate reductase subfamily, putative n=7
           Tax=Alphaproteobacteria RepID=B4WAM0_9CAUL
          Length = 359

 Score =  127 bits (318), Expect = 6e-28,   Method: Composition-based stats.
 Identities = 41/238 (17%), Positives = 82/238 (34%), Gaps = 69/238 (28%)

Query: 29  NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELL 88
               + S G +S+ +LH+  +         P++ ++TG  F +   +R +  KA G   +
Sbjct: 159 RVGAISSFGAESAALLHIVAET----DRDVPVVFLETGQHFLQTLSYRIQLTKALGLTDV 214

Query: 89  VHKNPEG-----VAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSR 143
               P+      +    + +   +    D+ K   L  A    GF+A   G +R +  +R
Sbjct: 215 RLVTPDANEKATLDARNDLWRTDADACCDLRKVRPLAHA--TVGFNAVITGRKRYQAATR 272

Query: 144 AKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENI 203
           A  + +   D                           +R+ PL++W  +D+  ++   ++
Sbjct: 273 AALKPFEVLD-------------------------GVLRINPLADWDAEDVEAWLEAHDL 307

Query: 204 DIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESN 261
              PL                                     +R++GCWP T AV+ +
Sbjct: 308 PRHPLVEQG---------------------------------YRSIGCWPCTRAVQDD 332


>UniRef50_Q2Y9X1 Phosphoadenylylsulfate reductase (Thioredoxin) n=9 Tax=Bacteria
           RepID=Q2Y9X1_NITMU
          Length = 256

 Score =  126 bits (317), Expect = 8e-28,   Method: Composition-based stats.
 Identities = 47/261 (18%), Positives = 82/261 (31%), Gaps = 73/261 (27%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L Q  AE   ++  V  ++       S G +  V+  L  + +        +  +DTG  
Sbjct: 7   LDQKIAEVRTLLERVQKDYLPATFANSFGAEDMVLTDLIARHY----PDIEMFTLDTGRL 62

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSA----------KHTDIMKTEG 118
            +E Y+   +  + YG  + V+  P+  A+      +G            K   I K E 
Sbjct: 63  PQETYDLMQQVTERYGIRIPVYF-PDAAAVEAYVAQNGPNAFYDSVDLRKKCCHIRKVEP 121

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           LK+AL      A   G RRD+  +R       F                           
Sbjct: 122 LKRALRDKR--AWITGLRRDQAPTRKGLVESEFDAENGLQ-------------------- 159

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
              +  PL +W++ D+W Y+   ++    L+                             
Sbjct: 160 ---KFSPLLDWSQADVWAYLKQFDVPYNALHDKG-------------------------- 190

Query: 239 IKKRMVRFRTLGCWPLTGAVE 259
                  + ++GC P T A+ 
Sbjct: 191 -------YTSIGCAPCTRAIT 204


>UniRef50_A3TKH9 Phosphoadenosine phosphosulfate reductase n=3 Tax=Actinomycetales
           RepID=A3TKH9_9MICO
          Length = 238

 Score =  126 bits (315), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 41/251 (16%), Positives = 79/251 (31%), Gaps = 68/251 (27%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A+++ + R  A  F   + +     +  V+ HL  +          +L ++TG+ F +  
Sbjct: 29  ADAVGVARWAAENFPGTLAVACSMAEG-VLPHLISQ----SAPGVDVLFLETGYHFSDTI 83

Query: 74  EFRDRTAKAYGCELL-----VHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
             R R A      ++     +    +    G   +    A    + K E L + L   G+
Sbjct: 84  GTRARVADELDVNVVDVLPELTVAEQDAKFGARLYERDPASCCAMRKMEPLGRTLA--GY 141

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
           +A   G RRDE  +R +  + +F ++                          +++ PL  
Sbjct: 142 EAWVTGVRRDEAPTRTETPLVTFDEKHGL-----------------------VKINPLVT 178

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           W+  D+  Y     + I  L                                     + +
Sbjct: 179 WSLDDVTDYALDNGVPINLL---------------------------------LSDGYPS 205

Query: 249 LGCWPLTGAVE 259
           +GC P T  V 
Sbjct: 206 IGCEPCTKRVA 216


>UniRef50_Q1AXE9 Phosphoadenylylsulfate reductase (Thioredoxin) n=1 Tax=Rubrobacter
           xylanophilus DSM 9941 RepID=Q1AXE9_RUBXD
          Length = 251

 Score =  125 bits (314), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 50/281 (17%), Positives = 89/281 (31%), Gaps = 85/281 (30%)

Query: 11  QLE-AESIHIIREVAAEFSNPVMLYS--IGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +LE A    ++R     F   + L     G +  V+L +  +     T    +  +DTG+
Sbjct: 25  ELEGAAPQEVLRWAVGFFGRRLTLSVSFGGPEGMVLLDMLSRI----TDDVWVFTLDTGF 80

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVA-----MGINPFVHGSAKHTDIMKTEGLKQA 122
            F E   FR+   + Y   L V +    V       G   +        ++ K E  ++ 
Sbjct: 81  LFEETVRFREEAMRRYRLPLRVVRPELSVEEQVERYGPRLWSCAPDICCEVRKVEPQRRW 140

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           L+   FDA   G RRD+  +RA   +  + + F  +                       +
Sbjct: 141 LS--NFDAWVTGIRRDQTAARADTPVVGWDEFFGVF-----------------------K 175

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           + PL++W+ + + +Y     + + PL                                  
Sbjct: 176 IAPLASWSRERVLRYAGEHGVPLNPL---------------------------------L 202

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
              + ++GC P T  V                    ER GR
Sbjct: 203 SRGYASIGCEPCTRPVR---------------EGEDERAGR 228


>UniRef50_A2C6A4 Phosphoadenosine phosphosulfate reductase n=27 Tax=cellular
           organisms RepID=A2C6A4_PROM3
          Length = 266

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 45/230 (19%), Positives = 81/230 (35%), Gaps = 38/230 (16%)

Query: 8   HLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           HL +L A+  + +     +F    V+  S G  S+V+LH+       G    P++ VDTG
Sbjct: 39  HLAKLSAQ--NRLEWALKQFGQGFVLTTSFGIQSAVLLHMLH--GLDGGSVVPVVWVDTG 94

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVA--------MGINPFVHGSAKHTDIMKTEG 118
           +   E Y + D+  +  G +L V ++    A        +     V     +  I K E 
Sbjct: 95  YLPAETYFYADQLTRQLGLDLKVVQSSMSPARMEAIYGRLWETGSVKDLETYHRIRKVEP 154

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L+QAL+         G R D+   R                                   
Sbjct: 155 LEQALDDLHVHCWASGVRSDQTDYRRSMAFLDLIR------------------------- 189

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
           + + + PL +WT ++++ Y+    +   PL+      V +         +
Sbjct: 190 DRLSLRPLLDWTPKEVFYYMQEHQLPQHPLFEKGYSTVGDLHSSAPDGGE 239


>UniRef50_Q467V4 Phosphoadenosine phosphosulfate reductase n=3 Tax=Methanosarcina
           RepID=Q467V4_METBF
          Length = 796

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 47/243 (19%), Positives = 77/243 (31%), Gaps = 46/243 (18%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVML----YSIGKDSSVMLHLARKAFYPGTLPF 58
           +    HL+ L   +I+ IR + +   +  +     +S GKDS V+L LAR +        
Sbjct: 360 KANKKHLQVLGKNAINTIRGIISRKEHKNLPVYVSFSGGKDSLVVLDLARSSLK--QREL 417

Query: 59  PLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN---PFVHGSAKHTDIMK 115
               ++TG +F E  EF     +     L+           +    P          + K
Sbjct: 418 KAFFLNTGIEFPETVEFVRNFCREREIPLVEANAGSTFREQVGKFGPPAKDFRWCCKVCK 477

Query: 116 T------EGLKQALNKYGFDA-----AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQR 164
                  E  K A ++ G           G R+ E  SRA+                   
Sbjct: 478 LASAGDFELGKGASSQKGAIGGVAYLTVDGKRKHESFSRARIAASE-------------- 523

Query: 165 PELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLM 224
                           + +FP+ +W   ++W YI    +   PLY        ER G  +
Sbjct: 524 --------TNPFVPAQLNIFPIRDWKAIEVWLYIHWRQLPYNPLYDLG----FERVGCWL 571

Query: 225 MID 227
              
Sbjct: 572 CPS 574


>UniRef50_Q2G577 Phosphoadenylylsulfate reductase (Thioredoxin) n=8
           Tax=Alphaproteobacteria RepID=Q2G577_NOVAD
          Length = 270

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 46/247 (18%), Positives = 80/247 (32%), Gaps = 67/247 (27%)

Query: 18  HIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRD 77
            +IR+  A   +  ++ S G +S+V+LHL  +         P+L ++TG  FRE   +RD
Sbjct: 41  SVIRDGLA--GDLAVVSSFGAESAVLLHLIAEV----DPSVPVLFLETGKHFRETVAYRD 94

Query: 78  RTAKAYGCELLVHKNPEGV-----AMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAF 132
                 G   L    P+             +        +I K E L +AL    FDA+ 
Sbjct: 95  ELIGFLGMTNLQIIEPDAAVIAKKDENGLRWSWDPDGCCEIRKVEPLARAL--LHFDASI 152

Query: 133 GGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQ 192
            G +  + K+RA    +       +                       +++ PL++W + 
Sbjct: 153 TGRKGFQSKTRAGLPRFEIDRSDAQ---------------------GRLKINPLASWDKT 191

Query: 193 DIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCW 252
            +  Y     +   PL                                     + ++GC 
Sbjct: 192 MLEAYFAEHGLPPHPLVAQG---------------------------------YPSIGCA 218

Query: 253 PLTGAVE 259
           P T  V 
Sbjct: 219 PCTSKVA 225


>UniRef50_B5Y5U1 Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP
           1055/1 RepID=B5Y5U1_PHATR
          Length = 272

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 38/234 (16%), Positives = 78/234 (33%), Gaps = 31/234 (13%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
            L+ LE +++  ++     + N V   ++     V+ HL  +  Y       ++ VDT  
Sbjct: 60  RLKHLEEQAMFALKIAVENYGNAVFPNAMIAGDVVITHLLSRLGYLENGKAKIMVVDTFH 119

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPE---------GVAMGINPFVHGSAKHTDIMKTEG 118
            F E  EF ++  + Y  +  V    +             G N +     ++  + K E 
Sbjct: 120 LFPETMEFLEKLEEHYNFKADVFCADKIPVGDKDAFDKRYGANLWKEDIDEYDRVCKVEP 179

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
            ++ L     D    G  R +   RA                          +      G
Sbjct: 180 FQRGLKTLKTDCMINGRTRWQGFERA----------------------WIDLFENAPIGG 217

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
              +  P++ WT +D + YI   ++   PL+      + +    + + +D  + 
Sbjct: 218 GLAKCNPIAYWTLEDTFDYIAKYDVPYHPLHEKGYPSIGDAKDTIPVPEDGSVR 271


>UniRef50_C4LKR1 Adenosine phosphosulfate reductase n=5 Tax=Actinomycetales
           RepID=C4LKR1_CORK4
          Length = 297

 Score =  124 bits (311), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 49/297 (16%), Positives = 93/297 (31%), Gaps = 86/297 (28%)

Query: 1   MDQIRLTHLRQLE-AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           M  + L +  +LE A +  I++          +  S+    +V+  LA K          
Sbjct: 76  MLNLALDYSAELEKASAEEIMQWAHDYVPKLAVTLSM--QDTVLADLAEKY----APAAD 129

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELL-----VHKNPEGVAMGINPFVHGSAKHTDIM 114
           L+ +DTG+ F E  +  D   + Y   LL     + +  +    G + +         + 
Sbjct: 130 LVFLDTGYHFAETLDVADAVERRYSNRLLRVVPHLTRREQDQRYGKDLYATDPTLCCHMR 189

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K   L++ L   G+ A   G +R +  SRA   +                          
Sbjct: 190 KVVPLQETLA--GYPAWVTGLKRVDAPSRAHTPVLE------------------------ 223

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
           I+K   +++ P+  WT+ D+  YI   ++   PL                          
Sbjct: 224 IDKAGRLKINPIITWTDDDVENYIVEHDLIRHPLTTQG---------------------- 261

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                      + ++GC   T  V+               +    R GR   +++  
Sbjct: 262 -----------YPSIGCATCTARVQ---------------AGEDPRSGRWQGKEKTE 292


>UniRef50_A4YFD1 Phosphoadenylylsulfate reductase (Thioredoxin) n=3 Tax=Archaea
           RepID=A4YFD1_METS5
          Length = 238

 Score =  124 bits (310), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 52/261 (19%), Positives = 90/261 (34%), Gaps = 73/261 (27%)

Query: 10  RQLEAESIH-IIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           R++E  S   II      F     +  S   +  V+L +A +          +  +DTG 
Sbjct: 14  REMETMSAERIIGWAVENFQDRLAIASSFQVEDMVILDIASRYGK-----VRVFTIDTGR 68

Query: 68  KFREMYEFRDRTAKAYGCELLVH-KNPEGVAM-----GINPFVHG---SAKHTDIMKTEG 118
             +E Y+  D   + YG ++ V    PE V       G+N F +            K + 
Sbjct: 69  LPQETYDLIDVVRERYGIKVEVFFPKPEDVEKMVREHGVNLFYNSVKLRQMCCWNRKVKP 128

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           LK+AL   G DA   G RR++ ++R+  R                              G
Sbjct: 129 LKRALE--GIDAWMTGLRREQWETRSSVRKIEVDT----------------------IHG 164

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +++ PL++WT + +W+Y+  +++    LY                             
Sbjct: 165 NIVKINPLADWTWEQVWKYVKEKDVPYNALYNKG-------------------------- 198

Query: 239 IKKRMVRFRTLGCWPLTGAVE 259
                  + ++GC P T  V 
Sbjct: 199 -------YMSIGCLPCTRPVR 212


>UniRef50_C5SCG2 Adenylylsulfate reductase, thioredoxin dependent n=3
           Tax=Proteobacteria RepID=C5SCG2_CHRVI
          Length = 256

 Score =  124 bits (310), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 47/256 (18%), Positives = 89/256 (34%), Gaps = 71/256 (27%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           EA +I ++ +V  E  + V   S+G +  V+  + R+      LP  +  +DTG    E 
Sbjct: 18  EAAAIELLSQVCRELDSIVFATSLGAEDMVLTEIIRR----ERLPIRIFTLDTGRLPTET 73

Query: 73  YEFRDRTAKAYGCEL-LVHKNPEGVAMGINPF--------VHGSAKHTDIMKTEGLKQAL 123
            E  +   + YG  +     +P+ +A  ++ +        V        + K E LK+AL
Sbjct: 74  LELIEVVERHYGTRIERYAPHPDAIADYVSRYGLDGFYDSVPARQACCRVRKLEPLKRAL 133

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G  A   G R ++  +RA+     +                              ++
Sbjct: 134 A--GQSAWVTGLRAEQSVTRAELPAREWDAANGL-----------------------EKI 168

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL++W+E ++W +I    +   PL+                                  
Sbjct: 169 NPLADWSEHEVWAFIRHHRVPYNPLHNQG------------------------------- 197

Query: 244 VRFRTLGCWPLTGAVE 259
             + ++GC P T A+ 
Sbjct: 198 --YPSIGCAPCTRAIT 211


>UniRef50_Q01NE3 Adenylylsulfate kinase / phosphoadenylylsulfate reductase
           (Thioredoxin) n=5 Tax=cellular organisms
           RepID=Q01NE3_SOLUE
          Length = 426

 Score =  123 bits (308), Expect = 8e-27,   Method: Composition-based stats.
 Identities = 48/289 (16%), Positives = 90/289 (31%), Gaps = 90/289 (31%)

Query: 6   LTHLRQLEAESI-HIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
           + +L + EA +   ++      F     +  S  K+   ++ LA +     +    +  +
Sbjct: 1   MDNLPEFEAATASEVLSWAIDTFGESFAIATSFQKEGMAIVDLASRI----SSEIRVFTL 56

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---------NPFVHGSAKHTDIM 114
           DTG    E Y+  +   + YG ++ V          +            V G  +  ++ 
Sbjct: 57  DTGRLPDETYQMMEMVRRRYGIQVEVIFPDRAEVESLVTIHGPNLFYASVPGRERCCEVR 116

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K   L++ L      A   G RRD+  +R+     +  D                     
Sbjct: 117 KVRPLERKLQSLK--AWATGLRRDQSATRSAVPKVARVD--------------------- 153

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                 +++ PL++WT   + +Y+   N+ + PLY                         
Sbjct: 154 ----GRLKLNPLADWTAAQVEEYLARHNVPLHPLYERG---------------------- 187

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                      + ++GC P T  VE                  SER GR
Sbjct: 188 -----------YTSIGCAPCTRPVEP---------------GESERAGR 210


>UniRef50_B8CCL3 Phosphoadenosine-phosphosulphate reductase n=1 Tax=Thalassiosira
           pseudonana RepID=B8CCL3_THAPS
          Length = 438

 Score =  122 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 39/231 (16%), Positives = 75/231 (32%), Gaps = 31/231 (13%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
            L+ LE +++  ++     + N V   ++    SV+ HL  +  Y       ++ VDT  
Sbjct: 65  RLKHLEEQAMFALKIAVENYGNAVFPNALIAGDSVITHLLHRMGYLKDGQAKVMVVDTFH 124

Query: 68  KFREMYEFRDRTAKAYGCELLVH---------KNPEGVAMGINPFVHGSAKHTDIMKTEG 118
            F E  EF       YG +  +          K       G + +     ++  + K E 
Sbjct: 125 LFPETMEFLREIEDFYGFKAEIFCAEGVPVGDKAAYDKKYGADLWKEDIEQYDKVCKVEP 184

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
            ++ L     D    G  R +   RA                          +      G
Sbjct: 185 FQRGLKTLNTDCMINGRTRWQGFERA----------------------WIDQFENAPIGG 222

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDN 229
              +  P++ WT +D + YI    +   PL+      + +    + + +D 
Sbjct: 223 GLAKCNPIAYWTLEDTFDYIAKYEVPHHPLHAKGYPSIGDAKDTIPIPEDG 273


>UniRef50_A1SNA9 Phosphoadenylylsulfate reductase (Thioredoxin) n=3 Tax=Bacteria
           RepID=A1SNA9_NOCSJ
          Length = 282

 Score =  122 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 50/277 (18%), Positives = 81/277 (29%), Gaps = 81/277 (29%)

Query: 2   DQIRLTHLRQLE-------AESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYP 53
           +++    L   E        E   +I     E      ++ ++  D  V+L +A +    
Sbjct: 23  ERVVFDDLEIGEIAVDLDDQEPEDVIAWALEELGDRIAIVTALQVDGMVVLDMATR---- 78

Query: 54  GTLPFPLLHVDTGWKFREMYEFRDRTAK-----AYGC------ELLVHKNPEGVAMGINP 102
                 ++ VDTG        F D          +        E+       GV +    
Sbjct: 79  LRPDIRVVTVDTGRLPDATLRFIDEARAHYPRTRWDVLHPDAAEVQAMVAERGVDL-FRS 137

Query: 103 FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
            V    +   + K   L QAL   G D  F G RRD+  SRA  +               
Sbjct: 138 SVADRMRCCQVRKVRPLTQALR--GLDGWFTGLRRDQWASRAAIKKVELD---------- 185

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
                        + G  ++V  L++W   D+W Y+    + + PLY             
Sbjct: 186 ------------HDHGGIVKVNALADWASADVWGYVEEHGVPVHPLYAQG---------- 223

Query: 223 LMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVE 259
                                  + +LGC P T  V 
Sbjct: 224 -----------------------YTSLGCGPCTRPVA 237


>UniRef50_B2GI28 Adenosine 5'-phosphosulfate reductase n=24 Tax=Actinomycetales
           RepID=B2GI28_KOCRD
          Length = 287

 Score =  122 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 39/251 (15%), Positives = 73/251 (29%), Gaps = 67/251 (26%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A+   ++   A  F   + +       +V+  L             +L ++TG+ F E  
Sbjct: 77  ADPDEVLAWAAETFGPRLAVACSMASDTVVPALVSTHLKN----VDVLFLETGYHFPETL 132

Query: 74  EFRDRTAKAYGCELL-----VHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
           + RD  A+ +   +      +    +    G             + K   L +AL   G+
Sbjct: 133 QTRDDFARDWPVNVRTLLPELTVPEQDAKYGAQLHDRDPGLCCGMRKVAPLDKALA--GY 190

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
           +A   G RR+E   RA             WD  +Q                 +++  + +
Sbjct: 191 EAWVTGLRREETPHRANAAPVE-------WDEHHQ----------------MVKINAIVD 227

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           WT   +  Y     + + PL                                     + +
Sbjct: 228 WTFDHVVAYAEENLVVVNPL---------------------------------LSQGYPS 254

Query: 249 LGCWPLTGAVE 259
           +GC P T  V 
Sbjct: 255 IGCAPCTRKVA 265


>UniRef50_P92979 5'-adenylylsulfate reductase 1, chloroplastic n=74 Tax=cellular
           organisms RepID=APR1_ARATH
          Length = 465

 Score =  121 bits (304), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 51/284 (17%), Positives = 95/284 (33%), Gaps = 78/284 (27%)

Query: 9   LRQLEAES-IHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
            ++LE  S + I+ +   ++ N + +   G +   ++  A    +    PF +  +DTG 
Sbjct: 97  AKKLENASPLEIMDKALEKYGNDIAIAFSGAEDVALIEYA----HLTGRPFRVFSLDTGR 152

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV---HGSAKHTDIMKTEGLK 120
              E Y F D   K YG  +          +G+      F     G  +   + K   L+
Sbjct: 153 LNPETYRFFDAVEKHYGIRIEYMFPDSVEVQGLVRSKGLFSFYEDGHQECCRVRKVRPLR 212

Query: 121 QALNKYGFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           +AL   G  A   G R+D+   +R++  +      F   D                  G 
Sbjct: 213 RALK--GLKAWITGQRKDQSPGTRSEIPVVQVDPVFEGLDGG---------------VGS 255

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
            ++  P++N    D+W ++   ++ +  L+ A                            
Sbjct: 256 LVKWNPVANVEGNDVWNFLRTMDVPVNTLHAAG--------------------------- 288

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                 + ++GC P T AV               +    ER+GR
Sbjct: 289 ------YISIGCEPCTKAV---------------LPGQHEREGR 311


>UniRef50_D2RH85 Phosphoadenosine phosphosulfate reductase n=1 Tax=Archaeoglobus
           profundus DSM 5631 RepID=D2RH85_ARCPR
          Length = 396

 Score =  119 bits (299), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 48/227 (21%), Positives = 82/227 (36%), Gaps = 40/227 (17%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +++ R+  L  +E  SI  IRE A   +N  + +S GKDS   L LA+KA          
Sbjct: 199 IEKNRMF-LEVMERISIKFIREHA---NNVAVPFSGGKDSLACLILAKKALG----DVKA 250

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           +++ T ++     E+ +R  K  G +L+V      V     P      +    +K E L+
Sbjct: 251 IYIKTNYEMPYTEEYIERVCKRLGVDLIVESVKFDVEKYGMP--THQNRWCTKLKMEALE 308

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           + +          G R  E + R +  +   R                            
Sbjct: 309 RVVKSEEVKTLIVGDRDAESRVRRERPVVFERIAKE------------------------ 344

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
             +FP+  W+   +  YI +  +D+ PLY         R G  +   
Sbjct: 345 --IFPIKYWSGAMVQLYILMNGLDLHPLYYKG----FYRLGCTICPS 385


>UniRef50_A6WVB8 Phosphoadenosine phosphosulfate reductase n=2 Tax=Ochrobactrum
           RepID=A6WVB8_OCHA4
          Length = 249

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 46/278 (16%), Positives = 85/278 (30%), Gaps = 86/278 (30%)

Query: 19  IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDR 78
           + RE+        ++ S G +S+V+LH+  +         P+L +DTG  FR   ++R  
Sbjct: 32  VTRELYE--GQIAVVSSFGAESAVLLHMISEI----DPATPVLFLDTGKHFRATLDYRHD 85

Query: 79  TAKAYGC-ELLVHKNPEGVAMGINPF----VHGSAKHTDIMKTEGLKQALNKYGFDAAFG 133
                G  ++      E      +PF    +    +   I K E + +A+  Y   A   
Sbjct: 86  LVDRLGLTDVQDILPLEDSLKADDPFGALSMTDKDRCCFIRKVEPMARAVAPYR--AWMT 143

Query: 134 GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQD 193
           G ++ +  +R    ++                          + G  IR+ PL+     D
Sbjct: 144 GRKQFQASTRESLPVFE-------------------------SVGSRIRINPLARLQAAD 178

Query: 194 IWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWP 253
           +  Y    ++   PL                                     +R++GC P
Sbjct: 179 LKAYAEKHDLPPHPLIAQG---------------------------------YRSIGCMP 205

Query: 254 LTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
            T  V                    +R GR    ++  
Sbjct: 206 CTRPVS---------------EGEDQRAGRWAGSEKTE 228


>UniRef50_Q2W561 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase/FAD
           synthetase and related enzyme n=3 Tax=Magnetospirillum
           RepID=Q2W561_MAGSA
          Length = 232

 Score =  119 bits (297), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 41/233 (17%), Positives = 76/233 (32%), Gaps = 66/233 (28%)

Query: 30  PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGC-ELL 88
             +  S G +S+V+L L  +         P++ +DT   F E   +R +     G   ++
Sbjct: 33  IAVTSSFGAESAVLLDLVAEV----DPGLPVIFLDTDELFDETIAYRTQLECHLGLTNVI 88

Query: 89  VHKNPEG-VAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKER 147
           V +  +  +      +     +  ++ K   L +A+  YG  A   G +R     R    
Sbjct: 89  VVRPTKAELRDAEELWRTDEDRCCELRKVRPLARAVAGYG--ALVDGRKRAHGAEREGLA 146

Query: 148 IYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVP 207
             S                           G  ++V PL+ W+ ++I  +    N+   P
Sbjct: 147 TLSGG-------------------------GGVLKVSPLAKWSAEEIEAHFIRRNLPRHP 181

Query: 208 LYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVES 260
           L   +                                 +R++GCWP T  VE+
Sbjct: 182 LVAQS---------------------------------YRSIGCWPCTRPVEA 201


>UniRef50_A5W608 Phosphoadenylylsulfate reductase (Thioredoxin) n=12 Tax=Bacteria
           RepID=A5W608_PSEP1
          Length = 244

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 46/276 (16%), Positives = 84/276 (30%), Gaps = 86/276 (31%)

Query: 19  IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDR 78
           I++     F + + +   G +  V++ +A K          +  +DTG    E Y F D+
Sbjct: 22  ILKLAFEHFGDDLWISFSGAEDVVLVDMAWK----LNKQVKVFSLDTGRLHPETYRFIDQ 77

Query: 79  TAKAYGCELLVHKNPEGVAMGINPFV----------HGSAKHTDIMKTEGLKQALNKYGF 128
             + Y   + +          ++PFV           G  +   I K E L++ L     
Sbjct: 78  VREQYNLPIEILSPDRA---KLDPFVKEKGLFSFYKDGHGECCGIRKIEPLRRKLAT--V 132

Query: 129 DAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
            A   G RRD+   +R++         F                     +    +  PL+
Sbjct: 133 SAWATGQRRDQSPGTRSQVAALEIDSAF------------------STPERTLYKFNPLA 174

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
             + +++W YI +  +    L+                                    F 
Sbjct: 175 QMSSEEVWGYIRMLELPYNSLHERG---------------------------------FI 201

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
           ++GC P T  V               +    ER+GR
Sbjct: 202 SIGCEPCTRPV---------------LPNQHEREGR 222


>UniRef50_UPI000038E1FC phosphoadenosine phosphosulfate reductase n=1 Tax=Ferroplasma
           acidarmanus fer1 RepID=UPI000038E1FC
          Length = 245

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 44/265 (16%), Positives = 78/265 (29%), Gaps = 86/265 (32%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL 87
              V   S+G +  V+  +  +      +   +  +DTG    E Y+  +      G +L
Sbjct: 25  KGAVFTSSLGLEDMVITDMIAR----NNINVEIATIDTGRLPDETYQLMETVRSEMGIDL 80

Query: 88  LVHKNPEGVAM------GINPFVHG---SAKHTDIMKTEGLKQALNKYGFDAAFGGARRD 138
            ++              GIN F H         ++ K + LK  L K        G R +
Sbjct: 81  KIYFPEREDVEDMINSRGINLFYHSLDNRHFCCNVRKVKPLKNILRKR--SVWITGIRAE 138

Query: 139 EEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYI 198
           +  +R   R   +    + W                       +V PL +W+  +IW Y+
Sbjct: 139 QTVARKNARKVEYVRDHNVW-----------------------KVNPLLDWSRDEIWSYV 175

Query: 199 WLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAV 258
            +  +    L+                                    ++++GC P T AV
Sbjct: 176 SIHKVPYNILFDQ---------------------------------NYKSIGCQPCTKAV 202

Query: 259 ESNAQTLPEIIEEMLVSTTSERQGR 283
             +                 ER GR
Sbjct: 203 GKD---------------DDERSGR 212


>UniRef50_Q11WI2 Phosphoadenylylsulfate reductase (Thioredoxin) n=3 Tax=Bacteria
           RepID=Q11WI2_CYTH3
          Length = 220

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 42/243 (17%), Positives = 71/243 (29%), Gaps = 69/243 (28%)

Query: 20  IREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRT 79
           + E   +        S    S V+LH+  +         P+  ++TG+ F E   +RD+ 
Sbjct: 10  LTEYQEKGLKLFTTSSFQTHSIVLLHILSEF----DPSIPVYFINTGYHFPETVLYRDQI 65

Query: 80  AKAYGCELLVH------KNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFG 133
           A  +  + +        +N +  A G   F         + K + L   L  Y  D    
Sbjct: 66  ADLFNLKNIKVVSSATPRNMQKDAEGRLLFTSDPDYCCYLNKVQPLDAVLPDY--DIWIN 123

Query: 134 GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQD 193
           G R D+   R    +                         Q    ++IR  P+ +W  + 
Sbjct: 124 GVRADQSAVRKSFSV------------------------EQPAPHDTIRFHPMLDWDVRM 159

Query: 194 IWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWP 253
           I +YI    I   PL                                     + ++GC P
Sbjct: 160 IEKYIKEHKIPRHPL---------------------------------EEKGYLSIGCEP 186

Query: 254 LTG 256
            T 
Sbjct: 187 CTR 189


>UniRef50_D1PAG4 ATP synthase F0, A subunit n=1 Tax=Prevotella copri DSM 18205
           RepID=D1PAG4_9BACT
          Length = 188

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 41/163 (25%), Positives = 64/163 (39%), Gaps = 34/163 (20%)

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVH-KNPEGVA-----MGINPF---VHGSAKH 110
           +  +DTG  F E Y+  D+T   YG  L V   N E V       GIN F   +    + 
Sbjct: 45  IFTLDTGRLFPETYQLIDKTNMTYGINLEVFFPNYEAVQQMVKEEGINLFYNSIESRHRC 104

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
             + K E LK+A+   G D    G R+ +  +R   ++  + D  +              
Sbjct: 105 CQVRKLEPLKRAMQ--GLDVWICGLRKQQSVTRKDMQVVEWDDIHNL------------- 149

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAE 213
                     I+V PL NW+E+D+ QY+   ++    L     
Sbjct: 150 ----------IKVNPLINWSEEDVEQYVKKHHVPYNKLQDKGY 182


>UniRef50_C9RRS4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Fibrobacter
           succinogenes subsp. succinogenes S85 RepID=C9RRS4_FIBSS
          Length = 579

 Score =  117 bits (293), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 55/238 (23%), Positives = 86/238 (36%), Gaps = 35/238 (14%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
                 L  L +E+   I++ AA +   N V+ +S GKDSSV   +  KA   G      
Sbjct: 152 AANKNRLNALISEAHAFIKKEAANYPEENIVLSFSGGKDSSVTADIVTKAL--GNPSLVH 209

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEG-----VAMGINPFVHGSAKHTDIMK 115
           +  +T  +F +  E+  R  K +   +      E      V   I P          + K
Sbjct: 210 IFGNTTLEFPQTVEYAKRFKKNHPFAIFETSINEDQNFMDVCEDIGPPARIMRWCCSMFK 269

Query: 116 TEGLKQALN---KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           T  + + LN   +      F G RR E  SR+K      R    +   K Q+        
Sbjct: 270 TGPITRVLNSLYRNQQILTFYGIRRAESASRSKYN----RVESGKESVKIQK-------- 317

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
                       P+ +W + DIW Y+  EN+D    Y        +R G     ++N+
Sbjct: 318 -------QTVASPIIDWKDIDIWLYLLAENVDFNDAYRLGY----DRVGCWCCPNNNQ 364


>UniRef50_C6WVG4 Adenylylsulfate reductase, thioredoxin dependent n=2
           Tax=Betaproteobacteria RepID=C6WVG4_METML
          Length = 259

 Score =  117 bits (292), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 46/261 (17%), Positives = 81/261 (31%), Gaps = 73/261 (27%)

Query: 10  RQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +Q   E + ++   A EF         S G +  V+  + ++      +   +  +DTG 
Sbjct: 35  KQKADEVLALLSSAANEFGANEVTFANSFGAEDMVLTDIIQRQ----KIAIEIFSLDTGR 90

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAM------GINPFVHG---SAKHTDIMKTEG 118
              E Y+   +T + Y  +L +               GIN F            + K E 
Sbjct: 91  LPVETYDLIAKTEQTYNTKLKIFFPQSDAVESYVRTNGINAFYESIDLRKACCFMRKVEP 150

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L++AL      A   G R ++  +R       F                           
Sbjct: 151 LQRALKDKK--AWVTGMRAEQSTTRVNLPFREFDSGNQL--------------------- 187

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
              +  PLSNWTE+++W YI + ++    L+                             
Sbjct: 188 --EKFNPLSNWTEKEVWAYIRMFDVPYNKLHDQF-------------------------- 219

Query: 239 IKKRMVRFRTLGCWPLTGAVE 259
                  + ++GC P T A+ 
Sbjct: 220 -------YPSIGCAPCTRAIA 233


>UniRef50_B5IDE7 Phosphoadenosine phosphosulfate reductase family protein n=2
           Tax=Aciduliprofundum boonei T469 RepID=B5IDE7_9EURY
          Length = 423

 Score =  117 bits (292), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 50/228 (21%), Positives = 83/228 (36%), Gaps = 46/228 (20%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
              L +LR++E E+I  I+   A++    + +S GKDS   L+LA KA          ++
Sbjct: 185 SANLGYLRKIENEAIERIKRAKADY----VAFSGGKDSETALYLAYKAGVK-----RAIY 235

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAM---GINPFVHGSAKHTDIMKTEGL 119
            +TG +F E   F    A   G EL+  +           +          T  +K E L
Sbjct: 236 ANTGLEFPETERFAYNFADYLGIELIEIRPKVDFWEMVEKLGIPTKDRRWCTKYLKLEEL 295

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           K+            G+R+ E   R                    RP+     N ++    
Sbjct: 296 KKF-----KGTIVDGSRKYESIGRM------------------LRPQESKLGNLRV---- 328

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
              ++P+ +W   D+W ++  + +   PLY        ER G  M   
Sbjct: 329 ---IYPILDWLALDVWLFLEWKKLPHNPLYDMGY----ERIGCFMCPS 369


>UniRef50_A3DLJ9 Phosphoadenosine phosphosulfate reductase n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DLJ9_STAMF
          Length = 457

 Score =  117 bits (292), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 50/251 (19%), Positives = 93/251 (37%), Gaps = 38/251 (15%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L   E  SI I+ +        ++ +S GKDS+  L L  K F         ++ DTG +
Sbjct: 222 LSLYEKISIKILEKYREWADTIIVPWSGGKDSTATLLLTLKVF--SKNKVKTIYADTGTE 279

Query: 69  FREMYEFRDRTAKAYGCELL--VHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           F   +++ +  A+  G E++       +G+     P      +     K + +++ + K 
Sbjct: 280 FPWTHKYINEIAERLGVEVIRVYAGIDKGILDEGYPMPRHDNRWCTYRKIKAIEETIGKL 339

Query: 127 --GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             G      G R  E ++R+                   RP ++      +     I V 
Sbjct: 340 SDGNILLVKGDRDGESRARS------------------MRPPIY------VENENKIVVT 375

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPV--------LERDGMLMMIDDNRIDLQPG 236
           P+  W+   I  Y+ L NI++ PLY      +           +  +MM D +  ++   
Sbjct: 376 PIKFWSAAHIQLYMLLNNIELNPLYYKGFYRIGCYICPALRSWEVYIMMNDPDLRNVLDK 435

Query: 237 EVIKKRMVRFR 247
             + K  +R R
Sbjct: 436 YPLYKLFIRIR 446


>UniRef50_A5PAV0 Phosphoadenosine phosphosulfate reductase n=1 Tax=Erythrobacter sp.
           SD-21 RepID=A5PAV0_9SPHN
          Length = 241

 Score =  117 bits (292), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 44/253 (17%), Positives = 83/253 (32%), Gaps = 70/253 (27%)

Query: 13  EAESIHIIREVA-AEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFR 70
           E +++  + E    ++     M+ S G +S V+L +  +         P+L  +TG  F 
Sbjct: 18  EGKTLAFLAESILRDYPGCVAMVSSFGAESIVLLDMVARI----NPNTPILLNETGMLFA 73

Query: 71  EMYEFRDRTAKAYGC-ELLVHKNPEGVAMGINP----FVHGSAKHTDIMKTEGLKQALNK 125
           E  E++   +   G   + + +         +P      + S     + K+E L++AL  
Sbjct: 74  ETLEYQREVSALLGLTNVQLVRPTRQRLAEEDPNGLLHRNDSDACCSLRKSEPLRRALAP 133

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
             FDA   G ++ +   RA+ +                                 +++ P
Sbjct: 134 --FDAWITGRKKFQNDKRAEMQPVEQDGA------------------------GRVKLNP 167

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           L++WT  DI  Y    N+   PL                                     
Sbjct: 168 LADWTPSDIRDYFDRYNLPRHPL---------------------------------VSQG 194

Query: 246 FRTLGCWPLTGAV 258
           + ++GC P T  V
Sbjct: 195 YPSIGCAPCTSRV 207


>UniRef50_Q0BUS4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Granulibacter
           bethesdensis CGDNIH1 RepID=Q0BUS4_GRABC
          Length = 249

 Score =  117 bits (292), Expect = 7e-25,   Method: Composition-based stats.
 Identities = 42/252 (16%), Positives = 79/252 (31%), Gaps = 71/252 (28%)

Query: 19  IIREVA-AEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFR 76
           ++R+    EF     ++ S G +S+++L L  +         P++ ++T   F E   +R
Sbjct: 41  LLRQAIMEEFAGRIAVVSSFGAESALLLALVAEI----DPATPIVFLETERHFPETLAYR 96

Query: 77  DRTAKAYGCELLVHKNPE-----GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAA 131
            + A   G   +   +P+             +   +     + K   L++AL+  GFDA 
Sbjct: 97  QQLANLLGLTGIRDIHPDPEEAAAQDPDAELWYFDADACCALRKVRPLEKALS--GFDAW 154

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
             G +R +  +RA         +F                          +  PL++W  
Sbjct: 155 ISGRKRHQASTRAALPFREVEGKF-------------------------TKFNPLADWGA 189

Query: 192 QDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGC 251
            DI   +    +   PL                                     + ++GC
Sbjct: 190 ADIEAEMTRRQLPRHPLVAKG---------------------------------YPSIGC 216

Query: 252 WPLTGAVESNAQ 263
            P T  V   A 
Sbjct: 217 APCTQPVAPGAD 228


>UniRef50_Q7M9C9 APS REDUCTASE n=1 Tax=Wolinella succinogenes RepID=Q7M9C9_WOLSU
          Length = 227

 Score =  116 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 44/240 (18%), Positives = 86/240 (35%), Gaps = 70/240 (29%)

Query: 30  PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL-L 88
             + +S   +  V+L L  K +      F +  ++TG  F +   F +   + +   +  
Sbjct: 19  ITLAFSHQAEDVVVLDLLLKHY---PRSFEVFTLETGKLFTQTLAFHEEVERFFNLTIQK 75

Query: 89  VHKNPEGVA--------MGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEE 140
            H +P+ +          G+   +    +   + K E LK+AL   G  A   G R ++ 
Sbjct: 76  YHPSPKALLELERELGEWGMRESLENRHRCCRVRKIEPLKEALK--GKSAWVTGLRAEQS 133

Query: 141 KSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWL 200
            +RA+ +   F + F                       + ++  PLS W+E ++++YI  
Sbjct: 134 ITRAELKSVEFDETF-----------------------DLLKFNPLSTWSETEVFEYIKE 170

Query: 201 ENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVES 260
             + + PLY                                    +R++GC P T A+E+
Sbjct: 171 HALPLHPLYTEG---------------------------------YRSIGCSPCTRAIEA 197


>UniRef50_Q5KLW1 Phosphoadenylyl-sulfate reductase (Thioredoxin), putative n=4
           Tax=Basidiomycota RepID=Q5KLW1_CRYNE
          Length = 272

 Score =  116 bits (289), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 45/283 (15%), Positives = 80/283 (28%), Gaps = 77/283 (27%)

Query: 18  HIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAF--YPGTLPFPLLHVDTGWKFREMYEF 75
            I+              + G   +  + +  K       T   PL+ +DT   F E    
Sbjct: 30  EILTWAVDNVDGLYQTTAFGLTGTAAVDMISKISLDREETHLVPLIFLDTLHHFPETLAL 89

Query: 76  RDRTAKAYGCELLVHKNPE-------GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
               A  Y   L ++  P         V  G   +      +  ++K E   +A  + G 
Sbjct: 90  AQTMADTYLAPLHIYTPPGVSTAEEFAVKYGEKLWETDEGAYDYLVKVEPAARAYKELGV 149

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
            A   G RR +   RA  ++    +R                          +++ PL  
Sbjct: 150 RAVITGRRRSQGADRADLKVLEIDER------------------------GLLKINPLIG 185

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           W+ +++ +YI  E +   PL                                     +R+
Sbjct: 186 WSFKEVKEYIDKEGVPYNPL---------------------------------LDKGYRS 212

Query: 249 LGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           +G    T   + NA            S  +ER GR   + +  
Sbjct: 213 IGDVHSTAPPDPNAA-----------SDAAERSGRWQGKAKTE 244


>UniRef50_B7R5I5 Iron-sulfur protein n=1 Tax=Thermococcus sp. AM4 RepID=B7R5I5_9EURY
          Length = 377

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 43/230 (18%), Positives = 82/230 (35%), Gaps = 40/230 (17%)

Query: 16  SIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           +++ +R    +F      + +S GKDS V LHLA +           +  DT  +  +  
Sbjct: 14  ALYFLR----QFPKSAIAVSFSGGKDSLVALHLASRVGIR-----RAVFSDTTIESSKTI 64

Query: 74  EFRDRTAKAYGCELLVHKNPEGVA---MGINPFVHGSAKHTDIMKTEGLKQALNKYGFDA 130
           E+        G ++ + +  +        + P           +K   L +   K+    
Sbjct: 65  EYIKEVETILGVKIDIVRPQKSFWELLPMLGPPSTRHRWCCPTIKYPQLSEYAKKHHIKY 124

Query: 131 AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWT 190
              G RR+E   R +                      +            I+V P+ +WT
Sbjct: 125 YITGLRRNESLIRME----------------------YKKIGKNPMIPYVIQVNPIIDWT 162

Query: 191 EQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
           E ++W+YI   N+ I P Y       L R+G ++    +  +L+  + I+
Sbjct: 163 ENEVWEYIKKYNLPIHPNYKLG----LSRNGCVICPYKSPKELRKLKEIE 208


>UniRef50_A3UHA4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Oceanicaulis
           alexandrii HTCC2633 RepID=A3UHA4_9RHOB
          Length = 249

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 46/266 (17%), Positives = 78/266 (29%), Gaps = 83/266 (31%)

Query: 31  VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGC-ELLV 89
            ++ S G +S+V+LHL  +A        P+L +DTG  F E   +RD  ++  G  ++  
Sbjct: 45  CVVSSYGAESAVILHLVAQA----KPDTPVLFMDTGQLFDETLAYRDALSERLGLTDVRT 100

Query: 90  HKNPEGVAMGINP----FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAK 145
            +         +P              I KT  L  AL  +       G +R     RA 
Sbjct: 101 LQPNPDHVKADDPDGVLHKTNPDLCCHIRKTLPLISALRPFKV--WISGRKRHHGGERAA 158

Query: 146 ERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDI 205
                 +D                           +++ PL +W+   I  Y    ++  
Sbjct: 159 LPRVEIQD-------------------------GKLKLNPLFDWSRDAINAYFETHDLPP 193

Query: 206 VPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTL 265
            P+                                     + ++GC P T  V+      
Sbjct: 194 HPMVAEG---------------------------------YPSIGCLPCTSQVKDP---- 216

Query: 266 PEIIEEMLVSTTSERQGRVIDRDQAG 291
                     T   R GR   +D+  
Sbjct: 217 ----------TDDPRAGRWAGQDKTE 232


>UniRef50_Q3YAU0 5'-adenylylsulfate reductase n=2 Tax=Viridiplantae
           RepID=Q3YAU0_9ASPA
          Length = 423

 Score =  115 bits (287), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 50/284 (17%), Positives = 89/284 (31%), Gaps = 78/284 (27%)

Query: 9   LRQLEAES-IHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
             +L+  S + I+    AEF N + +   G +   ++  AR        PF +  +DTG 
Sbjct: 47  AEELQNASPLEIMDRALAEFGNDIAIAFSGAEDVALIEYAR----LTGRPFRVFSLDTGR 102

Query: 68  KFREMYEFRDRTAKAYGCELLV----HKNPEGVAMGINPFV---HGSAKHTDIMKTEGLK 120
              E Y + +   K Y   +          + +      F     G  +   + K   L+
Sbjct: 103 LNPETYRYFNEVEKHYNIHIEYMFPDAVEVQALVRNKGLFSFYEDGHQECCRVRKVRPLR 162

Query: 121 QALNKYGFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           +AL   G  A   G R+D+   +RA   +      F   D                  G 
Sbjct: 163 RALK--GLRAWVTGQRKDQSPGTRAHIPVVQVDPTFEGSDGG---------------AGS 205

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
            I+  P++N   +D+W ++    + +  L+                              
Sbjct: 206 LIKWNPVANVDGKDVWNFLRTMEVPVNSLHAKG--------------------------- 238

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                 + ++GC P T  V               +    ER+GR
Sbjct: 239 ------YVSIGCEPCTRPV---------------LPGQHEREGR 261


>UniRef50_Q3B2L6 Phosphoadenylylsulfate reductase (Thioredoxin) n=2
           Tax=Chlorobium/Pelodictyon group RepID=Q3B2L6_PELLD
          Length = 250

 Score =  114 bits (286), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 45/260 (17%), Positives = 84/260 (32%), Gaps = 73/260 (28%)

Query: 15  ESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           +   ++     +F   +     S G +  V++ +  +      L  P+  +DTG   +E 
Sbjct: 17  QPEEVLSRAVRKFGISHLAFASSFGAEDQVIIDMICR----HGLDIPVFTIDTGRLPQET 72

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVAM------GINPFVHGSAK---HTDIMKTEGLKQAL 123
           Y+  D T   YG  + V               G N F     K        K + L++ L
Sbjct: 73  YDLLDATRMHYGISMEVLFPERAPVEDMLQRFGANLFYDSVEKRRMCCRTRKVQPLERRL 132

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           +    DA   G RR++  +R    +  + + F  +                       ++
Sbjct: 133 SS--LDAWICGLRREQSVTRTGTGVVEWDEAFGLF-----------------------KI 167

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL+ +TE +++ Y+   N+    L+                                  
Sbjct: 168 NPLAAFTEAEVFGYLLRHNVPSNALHRKG------------------------------- 196

Query: 244 VRFRTLGCWPLTGAVESNAQ 263
             + ++GC P T AVE  A 
Sbjct: 197 --YPSIGCAPCTRAVEPGAD 214


>UniRef50_Q3A3P4 Phosphoadenylylsulfate reductase (Thioredoxin) n=5 Tax=cellular
           organisms RepID=Q3A3P4_PELCD
          Length = 236

 Score =  114 bits (285), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 44/255 (17%), Positives = 77/255 (30%), Gaps = 71/255 (27%)

Query: 16  SIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           +  IIR         V M  S   +  V++ +  K          +  +DTG    E Y+
Sbjct: 20  AEDIIRAGIRAAGGEVSMASSFSVEDVVVIDMLHKI----APQVRVFAIDTGRLNEETYQ 75

Query: 75  FRDRTAKAYGCELLVHKNP----EGVAMGINPFV-----HGSAKHTDIMKTEGLKQALNK 125
             +     Y   +  +       E +      F          +   I K E L +AL+ 
Sbjct: 76  VAESVRARYDLRIDWYFPERQTVENLEREKGLFSFRESLDNRHECCRIRKVEPLGRALD- 134

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
            G      G RR +  +RA+       +                        G  +++ P
Sbjct: 135 -GLSGWVVGLRRQQSVTRAQLSPLEIDEA----------------------HGGIVKISP 171

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           L++W+E+ +W Y     + I  L+                                    
Sbjct: 172 LADWSEEQVWAYAEKHALPIHRLHRMG--------------------------------- 198

Query: 246 FRTLGCWPLTGAVES 260
           + ++GC P T AVE+
Sbjct: 199 YPSIGCAPCTRAVEA 213


>UniRef50_P56859 Phosphoadenosine phosphosulfate reductase n=12 Tax=Saccharomyceta
           RepID=MET16_EMENI
          Length = 302

 Score =  114 bits (284), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 48/300 (16%), Positives = 87/300 (29%), Gaps = 67/300 (22%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
            L+ LE +   ++R       +     + G    V++ +  K   P      L+ +DT  
Sbjct: 48  QLQFLEPQ--DVLRWCVTSLPHLYQTTAFGLTGLVIMDMLSKLSIPRPQMVNLIFLDTLH 105

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGV--------AMGINPFVHGSAKHTDIMKTEGL 119
            F E  +  D   K Y  + +    P+GV          G   +      +  I K E  
Sbjct: 106 HFPETLKLVDNVRKRYPLQHIHVYKPQGVETEEEFAKKHGERLWEKDDQLYDWIAKVEPA 165

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           ++A  +    A   G RR +   R    I    +                          
Sbjct: 166 QRAYRELNVHAVLTGRRRSQGGKRGDLDIIEVDEA------------------------G 201

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
            I++ PL+NWT   + QY+   +I    L                               
Sbjct: 202 LIKINPLANWTFDQVKQYVKENDIPYNEL------------------------------- 230

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQ 299
                 ++++G +  T  V+ N        +    +       R         ME K+++
Sbjct: 231 --LDKGYKSVGDYHSTSPVKENEDERSGRWKGQAKTECGIHNPRSKYAQYLMDMERKRQE 288


>UniRef50_A3UEI0 Phosphoadenosine phosphosulfate reductase n=1 Tax=Oceanicaulis
           alexandrii HTCC2633 RepID=A3UEI0_9RHOB
          Length = 366

 Score =  113 bits (283), Expect = 6e-24,   Method: Composition-based stats.
 Identities = 55/300 (18%), Positives = 91/300 (30%), Gaps = 89/300 (29%)

Query: 9   LRQLEAESIHII--REVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            ++L+  +   I  R          ML S G ++++ L L  +         P+L +DTG
Sbjct: 136 AKELDGATPEAILCRAAQVYGGRMAMLSSFGAEAALGLALVAEIASDT----PILFLDTG 191

Query: 67  WKFREMYEFRDRTAKAYGC-ELLVHKNPEGVAMGINP----FVHGSAKHTDIMKTEGLKQ 121
             F +   +RDR  K  G   L + K  E      +P    +        D+ K   L +
Sbjct: 192 MHFPQTLSYRDRLVKHLGLTNLHILKPDEAELRNEDPDNRLYDRDGVACCDLRKVRPLGR 251

Query: 122 ALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
           AL+   FDA   G +R     R       F                          GE +
Sbjct: 252 ALDP--FDALITGRKRYHGGQRGDIAAVEFD-------------------------GERV 284

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
           ++ P +  + QD+       ++   PL                                 
Sbjct: 285 KINPFAFLSPQDVADRYKALDLPRHPL--------------------------------- 311

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR--VIDRDQAGSMELKKRQ 299
               + ++GCWP T   +                    R GR    DRD+ G  +  + +
Sbjct: 312 AEDGYASIGCWPCTAPADEPGS----------------RDGRWAGQDRDECGIFDPARAE 355


>UniRef50_C7JH54 Phosphoadenosine phosphosulfate reductase n=8 Tax=Acetobacter
           pasteurianus RepID=C7JH54_ACEP3
          Length = 254

 Score =  113 bits (283), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 40/237 (16%), Positives = 73/237 (30%), Gaps = 68/237 (28%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL 87
               +L S G +S+++L +  +A         +L ++TG  F +  E+R   A       
Sbjct: 57  DRLAVLSSFGAESALLLAMVAEA----DPAMKVLFLNTGKHFPQTLEYRQNLADFLHLSN 112

Query: 88  LVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKS 142
           +    P     E        +         + K E LK A     ++A   G +R +  +
Sbjct: 113 VQDVAPQPQQVENRDPTGELWAFDPDACCALRKVEPLKVA--SLPYEALVTGRKRGQAVT 170

Query: 143 RAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN 202
           R+   I   R+                           +R+ PL+ W+ +DI Q +    
Sbjct: 171 RSTLEIVELRE------------------------DGQLRLNPLAFWSAEDITQEMQRRG 206

Query: 203 IDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVE 259
           +   PL                                     + ++GC P T  V+
Sbjct: 207 LPPHPLVAEG---------------------------------YLSIGCAPCTQPVD 230


>UniRef50_B1L7P4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Korarchaeum cryptofilum OPF8 RepID=B1L7P4_KORCO
          Length = 536

 Score =  113 bits (283), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 51/225 (22%), Positives = 81/225 (36%), Gaps = 39/225 (17%)

Query: 11  QLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFR 70
             E ESI +I     +    ++ +S GKDSSV+L LAR+      + F     DTG +  
Sbjct: 184 SKEFESIRMI-WRLTKGKRAIVSFSGGKDSSVLLELARR----SDINFLTYFNDTGLELP 238

Query: 71  EMYEFRDRTAKAYGCELLVHKNPEGVAMGIN---PFVHGSAKHTDIMKTEGLKQALNKYG 127
           E   F + T    GC+ ++    +     ++   P          ++K     +AL    
Sbjct: 239 ETISFVEST----GCD-IIGDAGDSFWRSLDRFGPPARDYRWCCKVIKLMPTYRALKHLR 293

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
                 G RR E  +R +                   P +W N          +   PL+
Sbjct: 294 PGLTLVGQRRYESSARMR------------------SPYMWRND----WLPGFLTAAPLN 331

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
           +W+    W YI + N+ + PLY        ER G  +       D
Sbjct: 332 DWSNLQTWLYIRVRNLRVNPLYFEG----FERLGCYLCPASRLSD 372


>UniRef50_C9KJN4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KJN4_9FIRM
          Length = 510

 Score =  113 bits (282), Expect = 9e-24,   Method: Composition-based stats.
 Identities = 56/262 (21%), Positives = 99/262 (37%), Gaps = 48/262 (18%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
            +   HL+ +  E+   IRE A+++   N V+ +S GKDS+V   +  KA          
Sbjct: 86  TVNRHHLQSIIDEAHQFIREEASKYPAENIVLSFSGGKDSTVTADIVTKAL--SNPSLVH 143

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELL-VHKNPEGVAMGINPFVHGSAK----HTDIMK 115
           +  +T  +F     + +R  K +   +  + +N E   M +   +   A+       + K
Sbjct: 144 IFGNTTLEFPTTLTYAERFRKNHPQAIFQIAQNREQNFMDMCKVIGPPARMMRWCCSMFK 203

Query: 116 TEGLKQALNKYGFD---AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           T  + + ++    +     F G RR E  SR+K                         YN
Sbjct: 204 TGPITRVISNLYRNQQILTFYGIRRYESVSRSK-------------------------YN 238

Query: 173 GQINKGESIRVF------PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI 226
                 ES+++       P+ NW + D+W YI  E ID    Y        +R G     
Sbjct: 239 RVEKNTESVKIQQQTVAAPIFNWKDIDVWLYILGEKIDFNDAYRLGY----DRVGCWCCP 294

Query: 227 DDN-RIDLQPGEVIKKRMVRFR 247
           ++N R        + +R  ++R
Sbjct: 295 NNNKRAQFLSNIYMPERSTKWR 316


>UniRef50_C5TAI7 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=1 Tax=Acidovorax
           delafieldii 2AN RepID=C5TAI7_ACIDE
          Length = 283

 Score =  113 bits (282), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 49/255 (19%), Positives = 81/255 (31%), Gaps = 70/255 (27%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           AE+  ++R+ AA         S+G +  V+ HL         L  P+  ++TG    E  
Sbjct: 33  AETQALLRQAAA-LGEVTQASSLGAEDVVITHLV----NALALDIPVFVLETGALHTETL 87

Query: 74  EFRDRTAKAYGCELLVHKNPEGV------AMGINPFVHG---SAKHTDIMKTEGLKQALN 124
              +RT       + V++             G +              I K E L +AL 
Sbjct: 88  ALLERTQAHSRAPVQVYRPQHEAVIHFIREHGQDAMYRSIELRKACCQIRKMEPLARALA 147

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             G      G RR++  +RA+  +                         ++      +  
Sbjct: 148 --GKKGWITGLRREQSNARAEVPLVD---------------------TSEVAAKGLTKFN 184

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL+NWT  D+W YI  + +D  PL+                                   
Sbjct: 185 PLANWTWGDVWHYIATQGVDYNPLHDQF-------------------------------- 212

Query: 245 RFRTLGCWPLTGAVE 259
            + ++GC P T AV 
Sbjct: 213 -YPSIGCAPCTRAVT 226


>UniRef50_B7UDE0 Adenosine phosphosulfate reductase n=1 Tax=Corynebacterium
           ammoniagenes RepID=B7UDE0_CORAM
          Length = 270

 Score =  112 bits (279), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 47/222 (21%), Positives = 81/222 (36%), Gaps = 37/222 (16%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A +  I+   A      + + ++  +++V+  LA KA     L   LL +DTG+ F E  
Sbjct: 61  ATATDIMAWAAEHAPGRLAV-TMSMENTVLAELAAKA----GLDADLLFIDTGFHFPETL 115

Query: 74  EFRDRTAKAY------GCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
           E  D   K Y        + L+    +    G   +    A +  + K E L  A+++Y 
Sbjct: 116 ETADAVEKRYPQLPLKRIKPLLSPEQQDEIYGPRMYSWDLAAYNRMRKVEPLNMAMDEY- 174

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
                 G RR + + RA+    S                          +   +++ P+ 
Sbjct: 175 -AGWITGLRRADSEHRAQAPALSLD------------------------RTGRLKISPII 209

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDN 229
            W   D  +YI  EN+ I PL L   R +        + D +
Sbjct: 210 TWDLADTDKYIADENLVIHPLTLQGYRSIGCAPVTFPVGDGD 251


>UniRef50_Q30U94 Phosphoadenylylsulfate reductase (Thioredoxin) n=4 Tax=Bacteria
           RepID=Q30U94_SULDN
          Length = 238

 Score =  112 bits (279), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 44/241 (18%), Positives = 78/241 (32%), Gaps = 71/241 (29%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL 87
            +  +  S G +  V+  +  K          +  +DTG    E Y+   RT   Y  ++
Sbjct: 30  DSIALSSSFGAEDQVLSDMVLKIESETN----IFTLDTGRLPYETYDVMQRTNLKYNTKI 85

Query: 88  LVH-KNPEGVAM--------GINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRD 138
            V+  N E +          G    V    +     K   LK+AL   G D    G R  
Sbjct: 86  KVYFPNSEDIEKLYQQQGINGFYDSVENRKECCYARKIAPLKRAL--MGIDIWITGLRAQ 143

Query: 139 EEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYI 198
           +  +R   +++ + +                           I++ PL  W+E+D+W+YI
Sbjct: 144 QSLTRKSTQLFEWDEENR-----------------------VIKLNPLILWSEEDVWRYI 180

Query: 199 WLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAV 258
              ++    L+ +                                  + ++GC P T AV
Sbjct: 181 NENSVPYNALHDSG---------------------------------YPSIGCAPCTRAV 207

Query: 259 E 259
           E
Sbjct: 208 E 208


>UniRef50_Q0EZE5 Phosphoadenosine phosphosulfate reductase n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0EZE5_9PROT
          Length = 245

 Score =  111 bits (278), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 47/224 (20%), Positives = 86/224 (38%), Gaps = 40/224 (17%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
            +    ++Q    S+ ++RE  A +    V   S+G  + V++ L  + + PG     ++
Sbjct: 2   TMVDDLVQQKVDASLLLLREAVARYGDRVVYASSLGSQAMVLIDLICR-YTPG---LRIV 57

Query: 62  HVDTGWKFREMYEFRDRTAKAYG--CELLVHKNPEGVAM----GINPFVHGSAK---HTD 112
            +DTG   ++ Y+  D   + YG    +L     E  AM    G+N F    A       
Sbjct: 58  TLDTGRLPQQTYDLMDLLRERYGPVLNVLFPDAGEVRAMVDEHGVNLFYRAVANRKLCCA 117

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           + K   L++ L+  G  A   G RRD+  +R++         +                 
Sbjct: 118 VRKVHPLQKELS--GMQAWITGRRRDQ-ANRSQITPVEDDPVYGLK-------------- 160

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
                    +  P+ +WTE DIW YI   ++    L+ +    +
Sbjct: 161 ---------KYNPMLDWTEADIWAYIRAHDLPYNSLHDSHYLSI 195


>UniRef50_B8FTN0 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=6 Tax=Clostridia
           RepID=B8FTN0_DESHD
          Length = 250

 Score =  111 bits (278), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 45/244 (18%), Positives = 76/244 (31%), Gaps = 71/244 (29%)

Query: 29  NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELL 88
              +  S+  +  V+  +  K          +  +DTG  F++ Y+  + T   Y     
Sbjct: 37  RIALASSLSIEDQVLTQMLLKIDARAR----IFFIDTGRNFQQTYDLMEETMSRYEFHYE 92

Query: 89  VHKNPEG------VAMGINPFVHG---SAKHTDIMKTEGLKQALNKYGFDAAFGGARRDE 139
           V+              G N F        K  ++ K   L++ L+    D    G R+++
Sbjct: 93  VYAPENSELEPFLAEYGPNAFYDKVELRQKCCELRKVRSLQRVLST--VDGWICGLRKEQ 150

Query: 140 EKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIW 199
             +R +  +  +  R                           +V PL+ W+E+ +W YI 
Sbjct: 151 SPTRQEIGLLEWDSRHA-----------------------IYKVNPLAAWSEEQVWAYIR 187

Query: 200 LENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVE 259
            ENI    LY                                    FR++GC P T AV 
Sbjct: 188 RENIPYSSLYNKG---------------------------------FRSIGCQPCTRAVA 214

Query: 260 SNAQ 263
             A 
Sbjct: 215 PGAD 218


>UniRef50_Q39RP8 Phosphoadenylylsulfate reductase (Thioredoxin) n=7 Tax=Bacteria
           RepID=Q39RP8_GEOMG
          Length = 235

 Score =  111 bits (277), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 41/256 (16%), Positives = 76/256 (29%), Gaps = 71/256 (27%)

Query: 14  AESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A    I+R   +     V +  S   +  +++ +A++       P  +  +DTG    E 
Sbjct: 16  ATPQDILRAGVSATEGSVKLACSFSVEDVIIIDMAKE----LGCPIGIFALDTGRLHEET 71

Query: 73  YEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV-----HGSAKHTDIMKTEGLKQAL 123
           YE  D   + Y   +  +       E +      F          +   I K E L +AL
Sbjct: 72  YEVADAITERYRIPIDWYFPRHETVEKLERDKGLFSFRESLDNRHECCHIRKVEPLGRAL 131

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G      G RR++  +R         +                        G  +++
Sbjct: 132 K--GLAGWITGLRREQSVTRTGLAPIESDEA----------------------NGGILKI 167

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL  W+E+ +W+Y     + +  L+                                  
Sbjct: 168 NPLLEWSEEQVWEYAEKRRVPVNRLHKQG------------------------------- 196

Query: 244 VRFRTLGCWPLTGAVE 259
             + ++GC P T  V 
Sbjct: 197 --YPSIGCAPCTRPVA 210


>UniRef50_Q8UH67 Phosphoadenosine phosphosulfate reductase n=10 Tax=Rhizobiales
           RepID=CYSH_AGRT5
          Length = 260

 Score =  111 bits (277), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 51/270 (18%), Positives = 84/270 (31%), Gaps = 86/270 (31%)

Query: 23  VAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKA 82
           VA      V   S+G +  V+      A     LP  ++ ++TG  F+E  +  D T + 
Sbjct: 38  VAGLGGRAVFTTSLGIEDQVI----TAAIGTHRLPIDVVTLETGRLFKETVDLIDETEER 93

Query: 83  YGCELLVHKNPE------GVAMGINPF---VHGSAKHTDIMKTEGLKQALNKYGFDAAFG 133
           +G E+   +  +          G+N F   V        + K   L +AL   G      
Sbjct: 94  FGIEIRRFRPEQDDIDAYAAKYGLNGFYESVEARHACCHVRKLIPLGKALE--GAAFWIT 151

Query: 134 GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQD 193
           G RR +  +RA      F                         +   I++  L++W  + 
Sbjct: 152 GLRRGQSGNRAATPFAEFD-----------------------AERNLIKINALADWDIEQ 188

Query: 194 IWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWP 253
           I  Y+  ENI + PL+                                    + ++GC P
Sbjct: 189 IRAYVAEENIPVNPLHQRG---------------------------------YPSIGCEP 215

Query: 254 LTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
            T A++                   ER GR
Sbjct: 216 CTRAIKP---------------GEPERAGR 230


>UniRef50_A1WQX9 Phosphoadenylylsulfate reductase (Thioredoxin) n=2
           Tax=Comamonadaceae RepID=A1WQX9_VEREI
          Length = 293

 Score =  111 bits (276), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 50/266 (18%), Positives = 85/266 (31%), Gaps = 55/266 (20%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVM-LYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
                A++  ++R+ AA  ++ V    S+G +  V+ HL         L  P+  ++TG 
Sbjct: 28  FDAKLAQTQALLRQAAALGADAVTQASSLGAEDVVITHL----INALQLDIPIFVLETGA 83

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGV------AMGINPFVHGSA---KHTDIMKTEG 118
              E     +RT       +  ++   G       + G +      A       I K E 
Sbjct: 84  LHTETLALLERTQAGSRAPVTPYRPETGAVMHFIRSHGQDAMYRSMALRKSCCGIRKLEP 143

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRD------RFHRWDPKNQRPELWHNYN 172
           L +AL   G  A   G RR++  +RA   +    +                         
Sbjct: 144 LARALA--GKSAWITGLRREQSGARADMPLIDLSEVAADGVDGADGADSAAGTAGAAGAG 201

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
           G        +  PL++WT  D+W YI    +D  PL+                       
Sbjct: 202 GHRGSAGLTKFIPLAHWTWGDLWHYIATHGVDYNPLHDRF-------------------- 241

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAV 258
                        + ++GC P T A+
Sbjct: 242 -------------YPSIGCAPCTRAI 254


>UniRef50_Q8TXP0 Predicted RNA modification enzyme consisting of a
           3-phosphoadenosine 5-phosphosulfate sulfotransferase
           fused to RNA-binding PUA domain n=1 Tax=Methanopyrus
           kandleri RepID=Q8TXP0_METKA
          Length = 524

 Score =  111 bits (276), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 51/234 (21%), Positives = 85/234 (36%), Gaps = 39/234 (16%)

Query: 10  RQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
            +LE E++   RE  +  S     +S GKDS V L +A +A          L VDTG + 
Sbjct: 220 ERLE-EAVTFARENVSP-SRTFASFSGGKDSLVTLVVAAEAGVE-----RALFVDTGMEL 272

Query: 70  REMYEFRDRTAKAYGCELLVHKNPEG----VAMGINPFVHGSAKHTDIMKTEGLKQALNK 125
            E  E  DR A+A G ++ + +        V   + P    +   T   K   + + +  
Sbjct: 273 PETVEAADRAAEAVGIDVEIVEGDPEIFHRVTEALLPPSRDNRWCTLAAKLTPVTRYVRS 332

Query: 126 YGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
                     G RR E ++R++                  R  +W            + V
Sbjct: 333 EFGRGCYTLVGVRRYESEARSE------------------RGRVWD----SDAVPGQVNV 370

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
            P+ +W+  D+W  +  +++   PLY        +R G  M       D +  E
Sbjct: 371 APIFDWSSLDVWLCVHSKDLPYNPLYDEG----FDRIGCYMCPASKVGDFRLSE 420


>UniRef50_Q0ASV0 Phosphoadenylylsulfate reductase (Thioredoxin) n=5
           Tax=Alphaproteobacteria RepID=Q0ASV0_MARMM
          Length = 374

 Score =  110 bits (275), Expect = 5e-23,   Method: Composition-based stats.
 Identities = 41/251 (16%), Positives = 74/251 (29%), Gaps = 71/251 (28%)

Query: 18  HIIREVAAE--FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEF 75
            I+R+           ++ S G +++V LH+  +         P++ +DTG  F +  ++
Sbjct: 156 EILRDAIENKWVGKIAIMSSFGAEAAVGLHMIAQI----DPATPVIFLDTGRLFAQTEQY 211

Query: 76  RDRTAKAYGCELLVHKNPEGVAMGIN-----PFVHGSAKHTDIMKTEGLKQALNKYGFDA 130
           + +     G   L    P+  A+         +         + K   L   +  Y  DA
Sbjct: 212 QRQLTDQLGLTNLRLLTPDADAVAEEDNDERLWRRDPDACCTLRKVRPLDGIIGDY--DA 269

Query: 131 AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWT 190
              G +R     R    +    +                           IRV PL+NW 
Sbjct: 270 LITGRKRFHGGGRMALPVVERIN-------------------------GRIRVNPLANWD 304

Query: 191 EQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLG 250
              I  Y    ++   PL                                   + + ++G
Sbjct: 305 AAAIEGYFQRFDLPRHPL---------------------------------TDMGYASIG 331

Query: 251 CWPLTGAVESN 261
           CW  T  V+ N
Sbjct: 332 CWTCTAPVQGN 342


>UniRef50_B8GIL3 Aminotransferase class V n=2 Tax=Archaea RepID=B8GIL3_METPE
          Length = 896

 Score =  110 bits (274), Expect = 8e-23,   Method: Composition-based stats.
 Identities = 44/219 (20%), Positives = 74/219 (33%), Gaps = 36/219 (16%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           HL+ LE  ++  I++   +     + +S GKDS+     A  A            ++TG 
Sbjct: 203 HLKNLERFAVRTIKQHMHDRPTINVSFSGGKDST-----AALALARRAGVTDAFFINTGL 257

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPE-GVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           +F E  +F        G E++              P    +      +K   LK+ L K 
Sbjct: 258 EFPETVDFVREQ----GVEVIDSGGDFWASVSKAGPPGKDNRWCCKSLKLHPLKRFLAKT 313

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           G      G R  E  +RA              +  +Q P          N    + + P+
Sbjct: 314 GPCVTVQGNRWYESWNRAGL------------EETSQNP----------NNPLQLNISPI 351

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
            NW   +++ Y+W   +    LY        ER G  + 
Sbjct: 352 RNWRAIEVFFYLWWRKVPFNSLYEEG----FERLGCYLC 386


>UniRef50_A8AC84 Phosphoadenosine phosphosulfate reductase n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8AC84_IGNH4
          Length = 646

 Score =  109 bits (273), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 44/226 (19%), Positives = 76/226 (33%), Gaps = 35/226 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           +    +L++L   S  ++ +        ++  S GKDS+    L  +      +   LL 
Sbjct: 192 KANEAYLQELLEWSRQVVSKAPEGVR--IVSLSGGKDSA----LVTQILKELGVEAKLLF 245

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN---PFVHGSAKHTDIMKTEGL 119
            DTG +  E  +  +  AK +G EL+V    +     +    P          ++K   +
Sbjct: 246 NDTGIELPETVKTAEEEAKHFGMELIVASAGDLFWRAVELFSPPARDFRWCCKVLKLGPI 305

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
            + L K+G    F G R  E   RAK         F                        
Sbjct: 306 ARTLIKFGNVVNFVGNRWWESLERAKATPIMKMKYF----------------------PT 343

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
              V P+  W +   + Y+  + + + PLY        +R G  M 
Sbjct: 344 ITTVNPILPWPQLLEFAYLIDKGVPLNPLYFKG----FDRVGCFMC 385


>UniRef50_Q1Q0N4 Similar to phosphoadenosine phosphosulfate reductase (PAPS
           reductase) n=1 Tax=Candidatus Kuenenia stuttgartiensis
           RepID=Q1Q0N4_9BACT
          Length = 290

 Score =  109 bits (273), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 44/252 (17%), Positives = 83/252 (32%), Gaps = 68/252 (26%)

Query: 16  SIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           ++  I+     F  + ++L S+ K +SV++H     FY   L   +L +DTG+ F E  +
Sbjct: 65  AVERIQWAVDNFGMDAILLSSMQKTASVLMH----YFYSLGLENYILFIDTGYHFAETLQ 120

Query: 75  FRDRTAKAYGCELLVHKNPEGVAMGINP-------FVHGSAKHTDIMKTEGLKQALNKYG 127
            RD     Y   ++       +             ++ G  +   + K       +   G
Sbjct: 121 LRDEFITRYKLNMVTLYPDLTIEQQEKLYGKKLYQYIDGQKECCRLRKEAPYLSYMKNNG 180

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
              +  G R+ E   R+K             +P  + P +           E   + PL 
Sbjct: 181 LMLSMVGLRQTEGGKRSKL------------EPLLRDPRI-----------EGYALHPLF 217

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           +W+++ I  Y+   +I I PL+                                    + 
Sbjct: 218 DWSDEQIESYLLENDIPIHPLH---------------------------------NKNYP 244

Query: 248 TLGCWPLTGAVE 259
           ++GC   T  V 
Sbjct: 245 SIGCECCTTPVR 256


>UniRef50_Q9JRT1 Phosphoadenosine phosphosulfate reductase n=103 Tax=Proteobacteria
           RepID=CYSH_NEIMB
          Length = 246

 Score =  109 bits (271), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 43/253 (16%), Positives = 72/253 (28%), Gaps = 72/253 (28%)

Query: 18  HIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRD 77
             +  +     +     S+  +  V+  L         L   +  +DTG    E     D
Sbjct: 33  QRLHRIVGSHRDARFASSLAAEDMVITDL----IAGENLNIGIFTLDTGLLHTETLNLLD 88

Query: 78  RTAKAY------GCELLVHKNPEGVAMGINPFVHGSAK----HTDIMKTEGLKQALNKYG 127
           R  +AY          +       V        + S +       I KTE L +A+   G
Sbjct: 89  RLGRAYPHLRIKRFRPVREDADRYVESKGRFAFYDSVEARRECCRIRKTEPLNRAIA--G 146

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
            DA   G RR++  +R +     +                              +  P+ 
Sbjct: 147 ADAWLTGQRREQSATRTELPFAEYDAGRGIG-----------------------KYNPIF 183

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           +W+E D+W YI   N+    LY                                    F 
Sbjct: 184 DWSEHDVWAYILANNVPYNDLYRQG---------------------------------FP 210

Query: 248 TLGCWPLTGAVES 260
           ++GC P T  V++
Sbjct: 211 SIGCDPCTRPVKA 223


>UniRef50_A6GTB0 Phosphoadenosine phosphosulfate reductase n=3 Tax=Proteobacteria
           RepID=A6GTB0_9BURK
          Length = 265

 Score =  108 bits (270), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 44/256 (17%), Positives = 83/256 (32%), Gaps = 74/256 (28%)

Query: 15  ESIHII-REVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           +++ I+    A EF +  +  S+  + +V+            L   +  ++TG   ++  
Sbjct: 44  QALEILLNNAANEFDSIALASSLAAEDNVLFD----VIARLKLNIRVFSLNTGRLHQQTL 99

Query: 74  EFRDRTAKAYGCELLVHKNPEGVA-------MGINPFVHGSA---KHTDIMKTEGLKQAL 123
           +        YG  +   + P+  A        G + F   +A   +   I K E L +AL
Sbjct: 100 DVAPALQAKYGQTVQWFE-PQAKAVETYVNTKGRDAFYESTALRKECCSIRKVEPLARAL 158

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G  A   G R+ +  +RA   +  F                              + 
Sbjct: 159 Q--GAKAWVTGQRQAQAATRATLPVREFDADRG-----------------------IEKF 193

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL++W+E D+W YI   ++ +  L+                                  
Sbjct: 194 NPLADWSEADVWTYIRQFDVPVNTLHFEG------------------------------- 222

Query: 244 VRFRTLGCWPLTGAVE 259
             F ++GC P T A+ 
Sbjct: 223 --FPSIGCEPCTRAIT 236


>UniRef50_Q3SNX7 Phosphoadenylylsulfate reductase (Thioredoxin) n=13 Tax=Rhizobiales
           RepID=Q3SNX7_NITWN
          Length = 254

 Score =  108 bits (269), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 43/235 (18%), Positives = 70/235 (29%), Gaps = 69/235 (29%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL 87
               ++ S G +S+ +L    K         P++ +DTGW F E   +RD    A G + 
Sbjct: 56  DRLALVSSFGTESAALL----KVMADVDPAIPVIFLDTGWLFEETLTYRDTLIAALGLKD 111

Query: 88  LVHKNPEGVAMGI-----NPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKS 142
           +    P   A+         +         I K E L +AL    F A   G +R +   
Sbjct: 112 VRSIPPSEDALKQEDPDRELWFSDPDSCCRIRKVEPLARALQP--FAAWINGRKRFQGGL 169

Query: 143 RAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN 202
           RA   +                           + G  ++  P +N + +DI        
Sbjct: 170 RADLPMVE-------------------------DDGARLKFNPFANASREDIEAIYASAK 204

Query: 203 IDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGA 257
           +   PL  +                                  FR++GC P T  
Sbjct: 205 LPPHPLVASG---------------------------------FRSVGCMPCTSR 226


>UniRef50_A9A540 Adenylylsulfate reductase, thioredoxin dependent n=14 Tax=Archaea
           RepID=A9A540_NITMS
          Length = 241

 Score =  108 bits (269), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 42/267 (15%), Positives = 80/267 (29%), Gaps = 71/267 (26%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVM-LYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           Q ++  L      +   ++ V+      V    S G + +V++ +  K        F   
Sbjct: 6   QEQVDDLNSKIKTAEEALQWVSDNLHPKVAKASSFGAEDAVIMDMMLKI----NPEFRFF 61

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLV------HKNPEGVAMGINPF---VHGSAKHTD 112
            +DTG   +E Y+  D   K Y   + V               G+N F   V       +
Sbjct: 62  TLDTGRLPQETYDIMDVLRKKYHITIEVLFPDTKEVEDMVKEKGLNLFYESVENRKLCCE 121

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           I K   + + L+    D    G RR++ K R    ++                       
Sbjct: 122 IRKVHPMNKMLST--LDGWITGLRREQTKIREDVTMFQLD-------------------- 159

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
                G  +++ P+ +WT   I ++I   ++    L                        
Sbjct: 160 --HGHGGILKINPIIDWTWDQIQEHIKKYDLPYNSL------------------------ 193

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAVE 259
                        + ++GC P T  ++
Sbjct: 194 ---------LDKGYPSIGCEPCTRPIK 211


>UniRef50_A6CAR6 Phosphoadenosine phosphosulfate reductase n=2 Tax=Planctomyces
           RepID=A6CAR6_9PLAN
          Length = 263

 Score =  107 bits (268), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 54/247 (21%), Positives = 85/247 (34%), Gaps = 46/247 (18%)

Query: 13  EAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
           E   + +I      F      L S+ +   V+ H+  +         P+L VDTG  F+E
Sbjct: 18  ERTPLELIHWAQEMFGTRLAALSSMQRAGCVVAHMLSEI----KADIPILFVDTGVLFQE 73

Query: 72  MYEFRDRTAKAYGCELLVHKNPEGVAMG------INPFVHGSAKHTDIMKTEGLKQALNK 125
             E RDR  + YG  ++     + +         +   V G  +  D+ KT+ L Q   +
Sbjct: 74  TLETRDRLIQEYGVNIVTLMPEKTMQEQTEELGILYLSVEGQEQCCDLRKTQPLIQVAEQ 133

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
           Y  DA  G  RR +   RA   I +                              +RV  
Sbjct: 134 Y--DALIGSLRRADGGQRANVPILAIDPAM-----------------------NCLRVNI 168

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           L++ ++++   Y+    I   PL+                I  NR      E    R  R
Sbjct: 169 LASLSKEEFQAYLEENQIITNPLHRQGY----------PTIGCNRCTTPVMESEPGRAGR 218

Query: 246 FRTLGCW 252
           +R LG W
Sbjct: 219 WRHLGPW 225


>UniRef50_C6QHX4 Adenylylsulfate reductase, thioredoxin dependent n=1
           Tax=Hyphomicrobium denitrificans ATCC 51888
           RepID=C6QHX4_9RHIZ
          Length = 269

 Score =  107 bits (268), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 43/255 (16%), Positives = 73/255 (28%), Gaps = 73/255 (28%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
            E I  IR             S+G +   + H    A         +  +DTG  F E  
Sbjct: 41  GERIKAIRAAID--GTIAFSTSLGIEDQAITH----AIAETGAEIDIFTLDTGRHFPETL 94

Query: 74  EFRDRTAKAYGCELLVHKNPEGVA---------MGINPFVHGSAKHTDIMKTEGLKQALN 124
           +    T   YG  + V                  G    V       ++ K   L +ALN
Sbjct: 95  DTLFDTEGKYGLRIRVMYPDAAEVEDLVANDGIYGFRYSVDARKACCEVRKVRPLNRALN 154

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             G  A   G RR++ + RA     ++                           + I++ 
Sbjct: 155 --GAAAWVTGLRREQSQGRAHVHFATYD-----------------------PAQKLIKLN 189

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P+++W+   +  Y+    I +  L+                                   
Sbjct: 190 PIADWSLATLEDYVATNKIPVNALHAKG-------------------------------- 217

Query: 245 RFRTLGCWPLTGAVE 259
            F ++GC P T A++
Sbjct: 218 -FPSIGCQPCTRAIK 231


>UniRef50_A5E7W2 Phosphoadenosine phosphosulfate reductase n=3
           Tax=Saccharomycetaceae RepID=A5E7W2_LODEL
          Length = 296

 Score =  107 bits (268), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 45/294 (15%), Positives = 83/294 (28%), Gaps = 82/294 (27%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           + I   + R +E     +IR     F N     + G     +  +  K      +   L+
Sbjct: 12  EHIDFLNKRLIELSPQDLIRWAYYTFPNLYQTTAFGLTGLAISDMISKI---PNVKIDLI 68

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA--------MGINPFVHGSAKHTDI 113
            +DT + F + YE  DR  + Y    +    P G+          G   +      +  +
Sbjct: 69  FLDTLYHFPQTYELLDRVQQKYPDSKINVFKPRGINTEEEFVKKYGDELWEKDDTYYDYL 128

Query: 114 MKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
           +K E  ++A      +    G R+ +  +R+   I    +                    
Sbjct: 129 VKVEPSQRAYKTLNANVVLTGRRKSQGGARSSLPILEKDE-------------------- 168

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
                  +++ PL NW    +  YI   N+    L                         
Sbjct: 169 ---VNNILKINPLWNWDFNQVKSYIDENNVPFNEL------------------------- 200

Query: 234 QPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDR 287
                     + ++++G W  T  V                    ER GR  D+
Sbjct: 201 --------LNLGYKSVGDWHSTVPVAD---------------GEDERAGRWKDK 231


>UniRef50_P18408 Phosphoadenosine phosphosulfate reductase n=50 Tax=Dikarya
           RepID=MET16_YEAST
          Length = 261

 Score =  107 bits (267), Expect = 5e-22,   Method: Composition-based stats.
 Identities = 47/258 (18%), Positives = 84/258 (32%), Gaps = 42/258 (16%)

Query: 1   MDQIRLTH----LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTL 56
           + Q +L H    L +LE     II      F +     + G    V + +  K      +
Sbjct: 12  VTQEQLDHWNEQLIKLETP-QEIIAWSIVTFPHLFQTTAFGLTGLVTIDMLSKLSEKYYM 70

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAY----GCELLVHKNPE-------GVAMGINPFVH 105
           P  LL +DT   F +    ++   K Y       + V+K              G   +  
Sbjct: 71  P-ELLFIDTLHHFPQTLTLKNEIEKKYYQPKNQTIHVYKPDGCESEADFASKYGDFLWEK 129

Query: 106 GSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRP 165
              K+  + K E   +A  +    A F G R+ +  +R++  I    +            
Sbjct: 130 DDDKYDYLAKVEPAHRAYKELHISAVFTGRRKSQGSARSQLSIIEIDELNG--------- 180

Query: 166 ELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
                          +++ PL NWT + + QYI   N+    L     R + +      +
Sbjct: 181 --------------ILKINPLINWTFEQVKQYIDANNVPYNELLDLGYRSIGDYHSTQPV 226

Query: 226 --IDDNRIDLQPGEVIKK 241
              +D R     G+   +
Sbjct: 227 KEGEDERAGRWKGKAKTE 244


>UniRef50_Q758M0 AEL259Wp n=1 Tax=Eremothecium gossypii RepID=Q758M0_ASHGO
          Length = 265

 Score =  107 bits (266), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 32/222 (14%), Positives = 61/222 (27%), Gaps = 34/222 (15%)

Query: 17  IHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFR 76
             ++      F +   + + G      + +  K         PL+ +DT   F +     
Sbjct: 34  AEVLHWAVTTFPHLYQMTAFGLTGLATIDMLSKLPALEEQMVPLIFIDTLHLFPQTLSLL 93

Query: 77  DRTAKAYGCEL-----------LVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNK 125
            +    Y   L           +  +       G   +     K+  I K E   +A   
Sbjct: 94  HQVEDRYYKPLSQSIHIFRPAGVSTEKEFAEKYGSCLWETDEDKYDFIAKVEPAHRAFRS 153

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
            G  A   G RR +  SR +       +                           +++ P
Sbjct: 154 LGVGAVLTGRRRSQGGSREQLNFVEVDE-----------------------VNAVLKINP 190

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
              W+   +W YI    I    L     + + +    L ++D
Sbjct: 191 FVTWSFDQVWSYILDNRIPYNELLNYGYKSIGDYHSTLPVVD 232


>UniRef50_B3T667 Putative phosphoadenosine phosphosulfate reductase family protein
           n=1 Tax=uncultured marine crenarchaeote HF4000_ANIW141O9
           RepID=B3T667_9ARCH
          Length = 263

 Score =  106 bits (265), Expect = 9e-22,   Method: Composition-based stats.
 Identities = 36/267 (13%), Positives = 75/267 (28%), Gaps = 71/267 (26%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAE-FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
             +++ L         +++           +  S G +   ++H+  K          + 
Sbjct: 30  TEQVSELNDKLKTPEEVLQWGLENIHPKLALASSFGAEDVCVIHMLSKINPEAR----VF 85

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV------AMGINPFVHGSAK---HTD 112
            +DTG   +E Y+  D   K Y  ++ +               G+N F   +        
Sbjct: 86  SLDTGRLNQETYDVMDEIRKKYNSKIEITFPDASEVIEMVQTHGLNLFYESAENRKLCCG 145

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           + K   L + L+    D    G R D+ ++R   +     +                   
Sbjct: 146 VRKVHPLNKMLST--LDGWITGLRSDQTQNRQASKKIEIDE------------------- 184

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
                   +++ P+ +W+      YI   +I    L                        
Sbjct: 185 ---QHDSMVKLNPILDWSWDQTMGYIKENDIPYNKLIDQG-------------------- 221

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAVE 259
                        F ++GC P T A++
Sbjct: 222 -------------FPSIGCEPCTRAIK 235


>UniRef50_A2BJV9 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase n=1
           Tax=Hyperthermus butylicus DSM 5456 RepID=A2BJV9_HYPBU
          Length = 472

 Score =  106 bits (264), Expect = 9e-22,   Method: Composition-based stats.
 Identities = 44/216 (20%), Positives = 78/216 (36%), Gaps = 33/216 (15%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           E  +I  +R    EF   ++ +S GKDS+  L         G     +++ DTG +F + 
Sbjct: 228 ERAAIRFLR-SLGEFDTIIVPWSGGKDSTAAL--LLALKAYGKDRVRVVYGDTGTEFPDS 284

Query: 73  YEFRDRTAKAYGCELLVHKNP-EGVAMGINPFVHGSAKHTDIMKTEGLKQ-ALN-KYGFD 129
             + +  A+  G E++      +   M   P      +   I+K + +++ A+    G  
Sbjct: 285 VRYVEEVAEKLGIEVVRAYAGIDKELMRGAPLPSHGDRWCTILKVKSIEEMAVKLAEGKT 344

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
               G R  E   R+                   RP +   Y      G+ + V PL  W
Sbjct: 345 LLVVGDRDAESPRRS------------------ARPPVRRAYT-----GDMLVVTPLRMW 381

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           +   +  YI +  + + P+Y         R G  M 
Sbjct: 382 SAAHVQLYIIMNGLPLNPMYYYG----FYRIGCYMC 413


>UniRef50_Q2RT16 Phosphoadenylylsulfate reductase (Thioredoxin) n=1
           Tax=Rhodospirillum rubrum ATCC 11170 RepID=Q2RT16_RHORT
          Length = 242

 Score =  106 bits (264), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 43/209 (20%), Positives = 75/209 (35%), Gaps = 37/209 (17%)

Query: 14  AESIHIIREVAAE--FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
           + +  I+ +V          ++ S G +++ +LH+   A  P T   P+L VDTG  F E
Sbjct: 21  SAAEAILEDVLKRAFVRRTALVSSFGTEAAALLHMVA-AIEPAT---PVLFVDTGRLFGE 76

Query: 72  MYEFRDRTAKAYGCELLVHKNPE----GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
              +RDR  +  G   +    PE         +  F   + +   + K   L++AL   G
Sbjct: 77  TLRYRDRLVERLGLTDVRSLKPEPRIAAEDQDLMLFSRDADRCCYLRKVLPLRKALE--G 134

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           FD    G +      RA+  +                             G  +++ PL+
Sbjct: 135 FDCWINGRKGHHGGGRAQMPVAEAD-------------------------GFLVKITPLA 169

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPV 216
            W   D+  Y    ++   PL+      V
Sbjct: 170 RWGADDVDAYYETHDLPRHPLWEDGFPSV 198


>UniRef50_Q8RG73 Phosphoadenosine phosphosulfate reductase n=3 Tax=Bacteria
           RepID=Q8RG73_FUSNN
          Length = 574

 Score =  106 bits (263), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 50/225 (22%), Positives = 79/225 (35%), Gaps = 35/225 (15%)

Query: 15  ESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           E+   I++ A ++     V+ +S GKDS+V+  L   A   G      +  DT  +F+  
Sbjct: 159 EANEFIKKTAKKYEEEKIVISFSGGKDSTVVADLVINAL--GNPSLVHIFGDTTLEFQTT 216

Query: 73  YEFRDRT-AKAYGCELLVHKNPE----GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
            E+ +R  A        + KN E     V   I P          + KT  + + LN   
Sbjct: 217 MEYAERYRASHRQAIFQIAKNNEQNFMSVCNDIGPPARMMRWCCSMFKTGPITRVLNNLY 276

Query: 128 FD---AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            +     F G R+ E  SR+K                             +   +     
Sbjct: 277 REERILTFYGIRKSESLSRSKYNRVEGNSE-------------------SVKIQKQTVAS 317

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDN 229
           P+  W++ DIW YI    ID    Y    R   +R G     ++N
Sbjct: 318 PIFFWSDIDIWLYILTRKIDFNEAY----RRGYDRVGCWCCPNNN 358


>UniRef50_C3KS73 Phosphoadenosine phosphosulfate reductase family protein n=2
           Tax=Clostridium botulinum B RepID=C3KS73_CLOB6
          Length = 703

 Score =  104 bits (260), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 39/232 (16%), Positives = 86/232 (37%), Gaps = 45/232 (19%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           E +S++I+++      N  +  S G DS + L+L RK        + ++  ++  ++ + 
Sbjct: 399 ELQSLYIMKKTLRLSKNLALSCSFGMDSILSLYLLRKVKKDN---YDIVFNNSLVEYNDT 455

Query: 73  YEFRDRTAKAYGCELLVH--------------------KNPEGVAMGINPFVHGSAKHTD 112
            +F+++  K +    +V                     K    +       V  S +   
Sbjct: 456 IKFKNKIIKEWDLTNVVETLPAKTYWELQKENGWNFQDKGDRTINKTTGKRVSASEQCCY 515

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
            +K   +   + +  +D+   G R DE ++R             + D        W+ + 
Sbjct: 516 FIKHLPMHNLITERKYDSDVAGVRADESRARLNA---------GKRDGVFYFASSWNLF- 565

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLM 224
                    RV P+  WT   +  Y+  +NI    +Y   ++ +L+ DG ++
Sbjct: 566 ---------RVNPILFWTNSMVIDYVKEKNIPYNEIY---DKKLLDDDGKVI 605


>UniRef50_C7G6A6 Phosphoadenosine phosphosulfate reductase n=3 Tax=Clostridiales
           RepID=C7G6A6_9FIRM
          Length = 525

 Score =  102 bits (254), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 47/225 (20%), Positives = 82/225 (36%), Gaps = 35/225 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +        +  E+ + IR+   EF   +  + +S GKDS+V  +L  +A    T     
Sbjct: 91  EANKERYEYITQEAGNYIRKAVGEFGAMDMFVSFSGGKDSTVTSNLVLRAL--STPQIMH 148

Query: 61  LHVDTGWKFREMYEFRDRTAKAY-GCELLVHKNPEGVAMG----INPFVHGSAKHTDIMK 115
           +  DT  +F   Y + +R  K +    ++  +N E         I P          + K
Sbjct: 149 IFGDTTLEFPFTYTYVERFKKNHPKTPVISARNKEKDFEELCKLIGPPSRVMRWCCTVFK 208

Query: 116 TEGLKQALNKYGFD----AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
           T  +++ +     D      F G RR E  SR+K            ++ ++  P++    
Sbjct: 209 TGTIQKKIRSLYRDKKQILTFYGIRRSESVSRSK------------YERESDSPKITKQR 256

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
                      + P+ +W + DIW YI    ID    Y      V
Sbjct: 257 I----------ISPIIDWMDFDIWLYILTTGIDFNDAYRLGYARV 291


>UniRef50_C5ETD1 Phosphoadenosine phosphosulfate reductase n=4 Tax=Clostridiales
           RepID=C5ETD1_9FIRM
          Length = 286

 Score =  102 bits (254), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 45/248 (18%), Positives = 73/248 (29%), Gaps = 28/248 (11%)

Query: 12  LEAESIHIIREVAAEFSN-----PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           LE +SI  I+  +           +  YS GKDS V+L L    F    + F   +  T 
Sbjct: 3   LETKSIERIKLASEMSKRYYDAPIICTYSGGKDSDVLLDL----FIRSGVEFEAHNSHTT 58

Query: 67  WKFREMYEFRDRT---AKAYGCELLVHKNPEGVAM----GINPFVHGSAKHTDIMKTEGL 119
               +   +        K  G   ++H  P  +         P         +I+K    
Sbjct: 59  VDAPDTVYYIREKFRGLKEKGIPCIIHMPPLSMWQLIVKKKMPPTRMQRYCCEILKENTT 118

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN-QRPELWHNYNGQINKG 178
              L          G R DE   R+K                     +       +    
Sbjct: 119 PDRL-------VSTGVRWDESTKRSKRGQLEAAAPKVENRITLMNDNDDKRLVIERCAIR 171

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +   P+ +WT +DIW YI   ++   PLY    +    R G +      +   +    
Sbjct: 172 GRVVSNPIIDWTHKDIWDYIRSNHMPYNPLYDMGYK----RVGCVGCPMAGKNRYKEFAD 227

Query: 239 IKKRMVRF 246
             K    +
Sbjct: 228 FPKYKAAY 235


>UniRef50_A9USG3 Predicted protein (Fragment) n=1 Tax=Monosiga brevicollis
           RepID=A9USG3_MONBE
          Length = 239

 Score =  102 bits (253), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 41/243 (16%), Positives = 79/243 (32%), Gaps = 47/243 (19%)

Query: 17  IHIIREVAAE--FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           + I+R + A+  + N V   S G    V+  +  +  +      P++ VDT + F E  +
Sbjct: 21  VQILRWMRAQPAWGNVVQFTSFGVSGMVITDIMTRLGFLT----PIVFVDTLYHFDETLD 76

Query: 75  FRDRTAKAYGCELLVHKNPEGVA-------MGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
            +    K Y  ++L +               G   +   S  +  + K E   +AL +  
Sbjct: 77  LKATVEKVYNRQVLAYGPQTSSDRSTFEEYYGQELWSKDSEFYHYLTKVEPTGRALTELE 136

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
            D    G RR +  SRA   +                          +     I++ P++
Sbjct: 137 VDVWITGRRRSQGSSRASLAVLE------------------------VASDGRIKINPMA 172

Query: 188 N--WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           +  W     W+Y+    +    L     + + +      +  D        E   +    
Sbjct: 173 HVDWAST--WKYVKSAGVPYNKLVDQGYKSIGDVHSTRPVGHDAP------ERSGRWSGE 224

Query: 246 FRT 248
           FRT
Sbjct: 225 FRT 227


>UniRef50_A3DMN4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DMN4_STAMF
          Length = 418

 Score =  102 bits (253), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 44/224 (19%), Positives = 77/224 (34%), Gaps = 40/224 (17%)

Query: 30  PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLV 89
            ++ +S GKDS V+LH+A+   + G      ++VDTG  F    ++ +  +   G E+ +
Sbjct: 217 VLVSFSGGKDSLVVLHMAK--MHYGEDMVRGIYVDTGVDFPHTRKYVEEISTMLGLEIDI 274

Query: 90  HKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG--FD--AAFGGARRDEEKSRAK 145
            +    + +        + +   + KT   K+ L  Y   FD      G R  E   RA+
Sbjct: 275 VRADVDILLPKKGLPTKNNRWCTLRKTHAFKKRLKWYKKRFDRILVLVGDRDSESVLRAR 334

Query: 146 ERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDI 205
           +     R+                           +   P+  W+   +  Y    ++ +
Sbjct: 335 KPPVRKRE-------------------------GYLEAAPIKQWSTFLVQLYHLKYDLPL 369

Query: 206 VPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
            PLYL        R G  +        L   E        FR L
Sbjct: 370 NPLYLKG----FYRLGCYIC-----PALTALEKHVMFNYMFREL 404


>UniRef50_B1I2U8 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I2U8_DESAP
          Length = 755

 Score =  101 bits (252), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 45/238 (18%), Positives = 79/238 (33%), Gaps = 41/238 (17%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV----MLYSIGKDSSVMLHLARKAFYPGTL 56
           M +   + LR +   ++  I+ V   + + V    + +S GKDS V+L L ++   P   
Sbjct: 85  MLERNDSILRDMVHATLDCIKAVHERYRDRVDTVAVAFSGGKDSLVLLDLVQRVLPPDE- 143

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYG-CELLVHKNP---EGVAMGINPFVHGSAKHTD 112
            F ++  DT  +    YE  +   K +G       + P           P          
Sbjct: 144 -FVVVFNDTTMELSATYEAVEAAKKRWGKLRFFTARAPRPARETWQEFGPPSRLHRWCCT 202

Query: 113 IMKTEGLKQALNKY----GFDAAF-GGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPEL 167
           + K+    + L +        A    G RR+E  +RA     S   +             
Sbjct: 203 VHKSAPTLRLLREMCGRPAVRALIYDGNRREESPARAAYPAVSEGKK------------- 249

Query: 168 WHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
                        I V PL NW   ++  Y+   ++ +   Y    R  + R G  + 
Sbjct: 250 ---------HPGQINVSPLLNWGLTEVHLYLMCRDLLLNRAY----RWGVVRVGCAVC 294


>UniRef50_C6Y361 Phosphoadenosine phosphosulfate reductase n=2 Tax=Bacteria
           RepID=C6Y361_PEDHD
          Length = 234

 Score =  101 bits (251), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 54/268 (20%), Positives = 89/268 (33%), Gaps = 79/268 (29%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
             ++  L  +EA     +R   AE+    V   S G +  V+ H+     +   LP  + 
Sbjct: 9   AEKIKDLDPVEA-----LRFFTAEYPGKIVFSTSFGWEDQVITHM----IFANDLPIEVF 59

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSA----------KHT 111
            ++TG  F E Y   +RT + Y   +  +  P+  A+       G +          +  
Sbjct: 60  TLETGRLFPETYYVWNRTLEIYKKPIHAYF-PQAEALQEMVDKKGPSSFYESVENRKECC 118

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            I K E L++AL   G D    G R ++  +R              WD +NQ        
Sbjct: 119 GIRKLEPLRRALK--GNDLWVTGIRSEQSLNR-------HDMANLEWDEQNQ-------- 161

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                    I+  P+  W+  ++ +YI   NI    L+                      
Sbjct: 162 --------LIKFHPIFFWSLAEVKEYIKKNNIVYNTLHDKG------------------- 194

Query: 232 DLQPGEVIKKRMVRFRTLGCWPLTGAVE 259
                         F ++GC P T AV 
Sbjct: 195 --------------FPSIGCAPCTRAVR 208


>UniRef50_A0Z1B4 Possible 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase n=1
           Tax=marine gamma proteobacterium HTCC2080
           RepID=A0Z1B4_9GAMM
          Length = 226

 Score =  101 bits (250), Expect = 4e-20,   Method: Composition-based stats.
 Identities = 40/203 (19%), Positives = 71/203 (34%), Gaps = 37/203 (18%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A    I+R   A+    V   S G  S+ MLHL  K         P++ +D+G+      
Sbjct: 25  ASPETIVRWALAQNLRVVTSTSFGTQSAAMLHLVSK----LGPSLPIIWIDSGFAPANTR 80

Query: 74  EFRDRTAKAYGCELLVHKNPE---------GVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           EF  +  +     L+ ++                  +      A+  +++K E  ++A++
Sbjct: 81  EFSRQLVEQLNLNLVTYRPNLTPLRCLHAISATDTEDLTEEQRAQLANLVKIEPFERAMS 140

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
                    G R +E   RAK R  S+ DR                          +++ 
Sbjct: 141 ALKPHIWLTGIRAEETSFRAKLRPASWDDR------------------------GMLKLA 176

Query: 185 PLSNWTEQDIWQYIWLENIDIVP 207
           P  + +E DI  Y+   N+   P
Sbjct: 177 PFLHSSEADIDAYLAQHNLPRGP 199


>UniRef50_B8D5B9 Phosphoadenosine phosphosulfate reductase n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D5B9_DESK1
          Length = 434

 Score = 99.9 bits (247), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 42/225 (18%), Positives = 77/225 (34%), Gaps = 32/225 (14%)

Query: 14  AESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
            E++  +++          + YS G DS+  L L+++A   G     +++VDTG     +
Sbjct: 205 NEAVGFLKKTLENVMDGIAVSYSGGADSTASLVLSQEAL--GHARIKVVYVDTGMDLPGV 262

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
            E+  R     G    V  +       I         +   T I+K E L++   ++   
Sbjct: 263 KEYALRILDKLGLIPYVVSSGLDPLNEIASRGLPTRDNRWCTRILKLEPLRRFYREHNIR 322

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
               G+              S         P+  R  L           E  R+ P+  W
Sbjct: 323 FVIDGS-------------RSRESSSRAETPRIGRNPLI---------PEVTRILPIKWW 360

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
           +   +  YI    I++ PLY         R G ++    +  +L+
Sbjct: 361 SRLLVQLYIVNRGIELNPLYNEG----FTRLGCILCPAMHPHELE 401


>UniRef50_D0JAV6 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=10
           Tax=Bacteroidetes RepID=D0JAV6_BLASB
          Length = 244

 Score = 99.5 bits (246), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 45/261 (17%), Positives = 78/261 (29%), Gaps = 73/261 (27%)

Query: 10  RQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +++++ S+    +  + F     V   S   +  ++ H          +P  +  +DTG 
Sbjct: 19  KEIKSPSVEEKLKTLSNFFPGKIVFSTSFNIEDQLISHFILS----NKIPIKIFTLDTGR 74

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV-----HGSAKHTDIMKTEG 118
            F E Y+  + T K YG  +  +       E       P           K   + K E 
Sbjct: 75  FFEETYKVWENTNKFYGYSISAYYPDQEKLEEFLSKNGPNSFYNNVKNRIKCCFLRKVEP 134

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           LK+AL          G R +    R K     +  ++H                      
Sbjct: 135 LKRALKGNFV--WITGLRAEHSLDRKKLNYLEWDSKYHL--------------------- 171

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             I+  PL NW  + I + +    +   PLY                             
Sbjct: 172 --IKYHPLYNWKLEVIEKMVKKHKVPYNPLYDKG-------------------------- 203

Query: 239 IKKRMVRFRTLGCWPLTGAVE 259
                  F ++GC P T +V+
Sbjct: 204 -------FLSIGCAPCTRSVK 217


>UniRef50_Q0RVM7 Probable phosphoadenylyl-sulfate reductase (Thioredoxin) n=3
           Tax=Rhodococcus RepID=Q0RVM7_RHOSR
          Length = 264

 Score = 99.5 bits (246), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 47/232 (20%), Positives = 82/232 (35%), Gaps = 32/232 (13%)

Query: 32  MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHK 91
           + +S GKDS ++L LAR+         P++  D+G  + E Y++       +  +L    
Sbjct: 47  VAFSGGKDSLIVLDLARRI----EPDVPVVFFDSGLDYPETYDYLTELTHTWRLDLHRIP 102

Query: 92  NPEGVAMGINPFVHG--------SAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSR 143
               +   +    H              +++ TE  ++A    G      G R DE  +R
Sbjct: 103 TDPPLLQVLADSGHWDHSAPVGTPLDLHEVLITEPARRAHQLLGP-GELWGVRADESAAR 161

Query: 144 AKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENI 203
                       H +    +R  +    +G    G      P+ NWT  D+W +I    +
Sbjct: 162 -----------RHLYTRGGRRDGIVTRADGTTAYG------PIWNWTIIDVWAHIARHQL 204

Query: 204 DIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLT 255
            I P+Y       +      +    +   L  G +   R   + TL C  LT
Sbjct: 205 PINPVYAKLRELGVPEQQHRLSHLIDGSHLDRGRLTWLRR-GWPTL-CEQLT 254


>UniRef50_C6E124 Phosphoadenosine phosphosulfate reductase n=1 Tax=Geobacter sp. M21
           RepID=C6E124_GEOSM
          Length = 784

 Score = 98.7 bits (244), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 46/266 (17%), Positives = 88/266 (33%), Gaps = 47/266 (17%)

Query: 15  ESIHIIREVAAEFSNPV----MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFR 70
           +++  I+E+   +        + +S GKDS V+L L  K      L  P++  DT  +  
Sbjct: 128 DTLKRIKEMYDAYVGKCNAVYIGFSGGKDSVVLLDLCHKVL---PLDVPVVFSDTDMELP 184

Query: 71  EMYEFRDRTAKAYGCE--LLVHKNPEGVAMGI--NPFVHGSAKHTDIMKTEGLKQALNKY 126
           + Y   +     Y     L V      +       P          + K+     AL + 
Sbjct: 185 DTYRVWEEIQNRYKGRPFLKVSAKTHALENWQLFGPPSQALRWCCSVHKSTPAILALKER 244

Query: 127 GFD-----AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
             +      AF G R +E + R+                       + +    +     +
Sbjct: 245 LGERSIKTLAFVGVRGEESQRRSG----------------------YEDIGDGLKSQSQV 282

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI-----DDNRIDLQPG 236
              P+  W+  ++W YI+  ++ +   Y    R  L R G LM        ++ I +   
Sbjct: 283 NAMPILAWSAHELWLYIFEHDLVVNEAY----RKGLPRVGCLMCPMSTDRQNDMIRMNFP 338

Query: 237 EVIKKRMVRFRTLGCWPLTGAVESNA 262
           E +       R+      T   +++A
Sbjct: 339 EEVAPFADAVRSTIDREFTSEDDADA 364


>UniRef50_B5Y6E1 Phosphoadenosine phosphosulfate reductase family protein n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y6E1_COPPD
          Length = 793

 Score = 98.7 bits (244), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 42/243 (17%), Positives = 76/243 (31%), Gaps = 46/243 (18%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV----MLYSIGKDSSVMLHLARKAFYPGTL 56
           M +     L  LE E+I  +  +   +   V    + +S GKDS V+L +  K   P   
Sbjct: 101 MLEKNKEQLEVLENEAIDFVNHIYKRYKGKVSAFVVSFSAGKDSQVILDIVSKVIPPEDY 160

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYG-----CELLVHKN---PEGVAMGINPFVHGSA 108
              ++  DT  +    YE  + T + Y       +    +N    E       P      
Sbjct: 161 F--VIFTDTTMEIPPTYEAFEETKRKYRETYPELKFYTARNWKPAEATWKEFGPPSRLLR 218

Query: 109 KHTDIMKTEGLKQALNK--YGFDA----AFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
               + K+  + + + +     D      F G R +E   R                   
Sbjct: 219 WCCSVHKSAPMIRLVREIVGRNDGVRIVVFDGVREEESTRR------------------- 259

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
              + +      +     I    +  WT  +++ YI    + +   Y    R  L+R G 
Sbjct: 260 ---KGYSRLAENVKHFTQINAEVIKRWTTTEVYTYILARELPLNTAY----RLGLDRVGC 312

Query: 223 LMM 225
            + 
Sbjct: 313 SVC 315


>UniRef50_A6EMB0 Phosphoadenosine phosphosulfate reductase n=1 Tax=unidentified
           eubacterium SCB49 RepID=A6EMB0_9BACT
          Length = 191

 Score = 98.3 bits (243), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 44/212 (20%), Positives = 70/212 (33%), Gaps = 34/212 (16%)

Query: 15  ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           E   II+       NP++  S GK S+ ++H    A         +L  DTG+     YE
Sbjct: 2   EPEEIIQFALHLSKNPLLTTSFGKYSACLIH----AVSTVKKDIAVLWCDTGYNTDATYE 57

Query: 75  FRDRTAKAYGCELLVHKNPEGVAMGIN----PFVHGSAKH--TDIMKTEGLKQALNKYGF 128
                +  Y   L V       A   N    P       H  ++I K    ++A+ K   
Sbjct: 58  HVSSLSSTYKLNLEVCSPQFTTAYINNKYGAPEFDNPNHHIISEITKVAPFQKAIKKIHP 117

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
           D      R+D+   R    I S+ +                           ++V P  N
Sbjct: 118 DVWLTNLRKDQNPYRESLDILSYSEE------------------------GILKVAPFFN 153

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
           W++  I  Y+   N+ I   Y    +    R+
Sbjct: 154 WSDSQILSYMNKNNLPIHVDYFDPIKASQSRE 185


>UniRef50_Q0RWS5 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=6
           Tax=Actinomycetales RepID=Q0RWS5_RHOSR
          Length = 284

 Score = 97.2 bits (240), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 44/227 (19%), Positives = 80/227 (35%), Gaps = 22/227 (9%)

Query: 32  MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHK 91
           + +S GKDS V LHL  +         P++  D+G ++ E Y +    A  +   L  H+
Sbjct: 43  LAFSGGKDSLVALHLTLQV----EPNIPVVFFDSGLEYPETYTYITALADTWNLNLEPHR 98

Query: 92  NPE---GVAMGINPFVHGSAKHTDIMKTE------GLKQALNKYGFDAAFGGARRDEEKS 142
                  V      + H         K          + A   +G      G R DE   
Sbjct: 99  ADPPLLTVLAQSGEWDHQQPTRATSQKLREILIGAPSRAAHATHGP-GEIWGVRADESPK 157

Query: 143 RAKERIYSFRDRFHRWDPKNQRP------ELWHNYNGQINKGESIRVF-PLSNWTEQDIW 195
               R   + +       ++         E   ++ G I++ +   VF P+ +W+  +IW
Sbjct: 158 -GTGRWSLYYNALSSHVTRDCDGCCTNTTEQRRHHGGLIDRADGTHVFGPMWDWSVDEIW 216

Query: 196 QYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
            YI    + + P+Y    R       + +    +   L+ G + + R
Sbjct: 217 AYIAHHQLPVNPVYDTLRRLGTPEKHLRVSHMLDGAFLEHGRITRLR 263


>UniRef50_A5INH9 Phosphoadenosine phosphosulfate reductase n=2 Tax=Thermotogaceae
           RepID=A5INH9_THEP1
          Length = 723

 Score = 97.2 bits (240), Expect = 6e-19,   Method: Composition-based stats.
 Identities = 46/239 (19%), Positives = 78/239 (32%), Gaps = 50/239 (20%)

Query: 9   LRQLEAESIHIIREVAAEFSNP----VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           L  LE E++  I      +        + YS GKDS V+L L  +          ++  D
Sbjct: 110 LFVLENEALDFIEHTYKVYKKKGYLFAVSYSGGKDSQVVLDLVTRVVPCD--DLVVIFSD 167

Query: 65  TGWKFREMYEFRDRTAKAY-----GCELLVHKNPE---GVAMGINPFVHGSAKHTDIMKT 116
           T  +    YE  ++T + Y     G +  V K P+          P          + KT
Sbjct: 168 TTMEIPYTYENVEKTKEEYEKRYPGLKFYVAKPPKPMMEFWKEFGPPSRVHRWCCTVAKT 227

Query: 117 EGLKQALNK-YGFDA---------AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPE 166
               + +   +G  A          F G R +E   R+                  QR  
Sbjct: 228 APFIRIIKAIFGKTAGENSKTKLIVFDGIRSEESARRSN----------------YQRLG 271

Query: 167 LWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           +   +  QIN         + +W   +++ Y++  N+ +        R  L R G  + 
Sbjct: 272 IEAKHILQINAEV------IRDWNTLEVFLYLYYRNLRMN----KGYRYGLNRVGCSVC 320


>UniRef50_B4D6P5 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=2 Tax=Bacteria
           RepID=B4D6P5_9BACT
          Length = 221

 Score = 96.8 bits (239), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 36/214 (16%), Positives = 70/214 (32%), Gaps = 38/214 (17%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYS-IGKDSSVMLHLARKAFYPGTLPFPL 60
           DQI   +    E   + I+R   A+     ++ +      +V+LHL  +         P+
Sbjct: 4   DQIAQANAELREKAPLDIVRWAIAQAGGRAIVSTNFRPYEAVILHLVTQV----QPNIPV 59

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAM-----GINPFVHGSAK-----H 110
           L VD G+     Y   +   K    ++         A      G  P      +      
Sbjct: 60  LWVDHGYNKPATYTHAEELKKLLNLDIRGFVPKMTAAHYDAVHGGAPEPTPENEERIKTF 119

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
           + +MK E  ++ + +          R+ +  +RA   I S    F               
Sbjct: 120 STVMKLEPFQRGMRELAPTVWITALRKVQNPNRAGLDIVSHDANFG-------------- 165

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENID 204
                    S++V P+  W ++D+  Y+   ++ 
Sbjct: 166 ---------SLKVSPVFYWNDKDMHNYLTEHHLP 190


>UniRef50_B8KW50 Phosphoadenosine phosphosulfate reductase n=1 Tax=gamma
           proteobacterium NOR51-B RepID=B8KW50_9GAMM
          Length = 228

 Score = 96.8 bits (239), Expect = 7e-19,   Method: Composition-based stats.
 Identities = 42/216 (19%), Positives = 71/216 (32%), Gaps = 36/216 (16%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           EA    I+    +     +   S G +++  LH    A        P++ VDTG+  R+ 
Sbjct: 34  EATPAEIVTWALSLDKRAIATTSFGVNAAATLH----AVVEQAPSLPVIWVDTGFNLRDT 89

Query: 73  YEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKH---TDIMKTEGLKQALN 124
           Y   D   +  G  L V+            +G  P    +  H   T+ +K E  ++A+ 
Sbjct: 90  YVQADAVTEQLGLNLHVYSPLITAERISAKLGGIPLPEDADNHRWFTEKVKLEPFRRAIA 149

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            +     F G R +E   R    I S   R                          I+V 
Sbjct: 150 DFRPQLWFSGIRAEETDHRRSLDIVSLDHR------------------------GIIKVA 185

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
           P   W++ +I  Y+    +     Y    +    R+
Sbjct: 186 PFFYWSDSEIDSYMLEHGLVSCQHYFDPTKVSSGRE 221


>UniRef50_Q97JS3 Similar to phospho-adenylylsulfate sulfotransferase n=1
           Tax=Clostridium acetobutylicum RepID=Q97JS3_CLOAB
          Length = 454

 Score = 96.8 bits (239), Expect = 9e-19,   Method: Composition-based stats.
 Identities = 54/257 (21%), Positives = 85/257 (33%), Gaps = 38/257 (14%)

Query: 3   QIRLTHLRQLEAESIH----IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYP--GTL 56
            +    L  LE  S+      I++    +    + +S GKDS V+ ++      P     
Sbjct: 87  SLNKNRLIFLENRSVSKSLKFIKKY--RYHEKRLAHSGGKDSDVLFYIFVNKILPLLKNK 144

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN------PFVHGSAKH 110
            + +   +T     + Y            +L +H   +G+   I            +   
Sbjct: 145 DYKIDFNNTTNDTAQTYLHIKELPND---KLNIHNPQKGIIEWITEDKNYFLPCVTNRNC 201

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
               K   +K  L+K        G RRDE   R+K       D       KN  PE W  
Sbjct: 202 CSNYKEGRMKDYLDKDKKYLLILGMRRDESPDRSKYDY----DLNKSMGEKNNVPENWK- 256

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI-DDN 229
                      R  P+  WT+ DIW YI + NI +  +Y         R G L+     +
Sbjct: 257 -----------RFLPILEWTDIDIWLYILMNNIKVNHMYKLGY----NRCGCLICPFQSD 301

Query: 230 RIDLQPGEVIKKRMVRF 246
            IDL        +  R+
Sbjct: 302 YIDLLTQYFYPFQWSRW 318


>UniRef50_Q0VNW4 Phosphoadenosine phosphosulfate reductase n=5 Tax=Proteobacteria
           RepID=Q0VNW4_ALCBS
          Length = 236

 Score = 94.8 bits (234), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 30/205 (14%), Positives = 64/205 (31%), Gaps = 36/205 (17%)

Query: 17  IHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
              IR V  +F     ++  S    S+  LH+             +  +DTG+ F +  +
Sbjct: 35  AERIRRVYEDFAPDRIMVTSSFAATSAYFLHIISTI----RPQQSVHFIDTGYHFADTLK 90

Query: 75  FRDRTAKAYGCELLVHKNPEG---VAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAA 131
           ++D   + +G  ++          V+     +         + K   L++A  K  +D  
Sbjct: 91  YKDYLIERFGLNVVDVTPDPDHHQVSQENRMWETDPDLCCQVNKVNPLEEA--KENYDLW 148

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
                  + + RA   ++  R                            I+  P+ + T+
Sbjct: 149 ISSLMGWQTEHRAGLEVFEERR-------------------------GMIKFNPMIDVTK 183

Query: 192 QDIWQYIWLENIDIVPLYLAAERPV 216
           +    YI   ++   PL       +
Sbjct: 184 EQRDAYIKEHDLPFHPLVAQGFDSI 208


>UniRef50_A8A8R5 Phosphoadenosine phosphosulfate reductase n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8A8R5_IGNH4
          Length = 421

 Score = 94.8 bits (234), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 36/192 (18%), Positives = 71/192 (36%), Gaps = 28/192 (14%)

Query: 22  EVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAK 81
           +V       V+ +S GKDS+  L +A++A          ++VDTG       ++ +  ++
Sbjct: 218 KVLEGCERAVVPWSGGKDSTAALLIAKRACDE----VTAVYVDTGVDMYLNRKYVELWSQ 273

Query: 82  AYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEK 141
               +L++ + P    +          +    +K +GL++A+ +   D    G R  E +
Sbjct: 274 KLNVDLIIKEVPVKSQIFQRGLPTKEDRWCTALKLKGLEEAIREVKPDYIVVGDRDAESQ 333

Query: 142 SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLE 201
           +R      S R     W+                  G      PL  W+   +  Y++  
Sbjct: 334 AR------SARWEERAWE------------------GVGTVKAPLKLWSAMMVQLYLFKN 369

Query: 202 NIDIVPLYLAAE 213
            +   PLY +  
Sbjct: 370 KVFPNPLYASGF 381


>UniRef50_D1HPZ6 Whole genome shotgun sequence of line PN40024,
           scaffold_116.assembly12x (Fragment) n=1 Tax=Vitis
           vinifera RepID=D1HPZ6_VITVI
          Length = 438

 Score = 94.1 bits (232), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 48/278 (17%), Positives = 83/278 (29%), Gaps = 98/278 (35%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A  + I+ +  A+F N + +   G +   ++  AR                TG  FR   
Sbjct: 96  ASPLEIMDKALAKFGNDIAIAFSGAEDIALIEYARL---------------TGRPFR--- 137

Query: 74  EFRDRTAKAYGCELLV----HKNPEGVAMGINPFV---HGSAKHTDIMKTEGLKQALNKY 126
                  K YG  +          +G+      F     G  +   + K   L++AL   
Sbjct: 138 -------KHYGIRIEYMFPDAVEVQGLVRSKGLFSFYEDGHQECCRVRKVRPLRRALK-- 188

Query: 127 GFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
           G  A   G R+D+   +RA+  +      F   D                  G  ++  P
Sbjct: 189 GLRAWITGQRKDQSPGTRAEVPVVQVDPAFEGLDGG---------------VGSLVKWNP 233

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           ++N    DIW ++   N+ +  L+                                    
Sbjct: 234 VANVQGMDIWNFLRAMNVPVNSLH---------------------------------SKG 260

Query: 246 FRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
           + ++GC P T  V               +    ER+GR
Sbjct: 261 YISIGCEPCTRPV---------------LPGQHEREGR 283


>UniRef50_D0J215 Phosphoadenosine phosphosulfate reductase n=9 Tax=Proteobacteria
           RepID=D0J215_COMTE
          Length = 215

 Score = 94.1 bits (232), Expect = 5e-18,   Method: Composition-based stats.
 Identities = 38/217 (17%), Positives = 75/217 (34%), Gaps = 35/217 (16%)

Query: 11  QLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFR 70
           +L  ++  ++          ++  +     +V+LH+  +A        P++ +D G+   
Sbjct: 20  ELGRDAQALVNWAVGLDQPTIVTTNFRPFEAVILHMVTRA----NPDVPVVWMDNGYNTE 75

Query: 71  EMYEFRDRTAKAYGCELLVHKNPEGVA-----MGINPFVHGS--AKHTDIMKTEGLKQAL 123
             Y F D   K  G  L ++      A      G  P +     A  T+ +K E   +AL
Sbjct: 76  ATYRFADAVTKQLGLNLKIYLPLRSRAHREAVEGATPALDDPRHAAFTEEVKLEPFARAL 135

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
            +      F   R  +   RA+    S                        IN    I+V
Sbjct: 136 RETAPKVWFTALRATDTAVRAQMEPVS------------------------INPDGLIKV 171

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
            PL +W+ +++++Y     +     Y+   +    R+
Sbjct: 172 APLLHWSSKELYEYCEKHGLPNNFDYVDPTKGEDNRE 208


>UniRef50_A1UQ75 Phosphoadenosine phosphosulfate reductase n=3 Tax=Mycobacterium
           RepID=A1UQ75_MYCSK
          Length = 278

 Score = 94.1 bits (232), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 14/187 (7%)

Query: 32  MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHK 91
           + +S GKDS+V++ LAR+         P++  D+G +F E  E+  + A A+  +  V  
Sbjct: 43  VSWSGGKDSTVVVDLARQV----DPHVPVVFFDSGLQFPETIEYLQQLASAWRLDYHVVT 98

Query: 92  NPEG---VAMGINPFVHGSAKHT------DIMKTEGLKQALNKYGFDAAFGGARRDEEKS 142
                  V +    F H +          DIM T    +A  ++G   +  G R +E   
Sbjct: 99  ADPDLLTVLIAGGGFDHHAVDRRLRGQLADIMITGPAAEAHRRHG-RGSLWGVRAEESHG 157

Query: 143 RAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN 202
           R            H     ++                ++   P+ +W    +++Y+    
Sbjct: 158 RRMLYRRGLAAETHARQNCSREDVRARAGGVVRRADGTVTYGPIWDWQRSHVFEYLAGRG 217

Query: 203 IDIVPLY 209
           I+  PLY
Sbjct: 218 IEPNPLY 224


>UniRef50_UPI0001C3554A hypothetical protein ChatD1_24037 n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C3554A
          Length = 293

 Score = 94.1 bits (232), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 49/255 (19%), Positives = 87/255 (34%), Gaps = 29/255 (11%)

Query: 1   MDQIRL-THLRQLEAESIHIIR---EVAAEFSNPV--MLYSIGKDSSVMLHLARKAFYPG 54
           M+Q RL          +I + +   + A  +      + +S GKDS V+  LA+ A    
Sbjct: 1   MEQYRLFDDFSDKVKRAIQLFQMFEDAAVRYHKDGYYLAFSGGKDSVVLYVLAKMA---- 56

Query: 55  TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIM 114
            + F   +  T     E+  F          E       + +     P +  +    +++
Sbjct: 57  HVKFQAHYHLTTVDPPELVWFIREAFPDVKVEYPELTMWDLIVKKQMPPLRTARYCCEVL 116

Query: 115 KTEGLKQALNKYGFDAAFG--GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           K         + G + AF   G R +E + RA         +           E      
Sbjct: 117 K---------EGGGEGAFTVTGVRWEESRKRANRDFLEIHKKKGAIYLNCDNEEDRRKLE 167

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
               KG+ I + P+ +WTE+DIW +I    +    LY         R G +         
Sbjct: 168 ICSLKGKRI-LNPIIDWTEEDIWYFIRKYQVPYCCLYDQG----FCRIGCIGC---PLAS 219

Query: 233 LQPGEVIKKRMVRFR 247
           ++  E   +R  ++R
Sbjct: 220 IRSREREFERYPKYR 234


>UniRef50_D0J9F7 Phosphoadenosine phosphosulphate reductase n=1 Tax=Blattabacterium
           sp. (Periplaneta americana) str. BPLAN
           RepID=D0J9F7_BLASP
          Length = 240

 Score = 93.7 bits (231), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 44/263 (16%), Positives = 75/263 (28%), Gaps = 73/263 (27%)

Query: 9   LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            +++E+ SI    ++ +E      V   S   +  ++ H          +   +  +DTG
Sbjct: 13  AKKIESYSIEEKLKILSEIFPGRIVFSTSFNIEDQLISHFILN----EKILIKIFTLDTG 68

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV-----HGSAKHTDIMKTE 117
             F+E Y+    T K Y   +  +       E       P           K   + K E
Sbjct: 69  RIFKETYQVWSDTNKFYNYSISAYYPNTKRLENFLSEKGPNSFYENVQNRMKCCFLRKVE 128

Query: 118 GLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
            L++AL   G      G R +    R       +   +                      
Sbjct: 129 PLRRALQ--GNAIWITGLRSEHSLERKNLNFLEWDSNYQL-------------------- 166

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
              I+  PL NW    I + I   NI    LY                            
Sbjct: 167 ---IKYHPLFNWKSDKIRKLIKKYNIPYNHLYNKG------------------------- 198

Query: 238 VIKKRMVRFRTLGCWPLTGAVES 260
                   + ++GC P T +V++
Sbjct: 199 --------YLSIGCAPCTRSVKN 213


>UniRef50_B8GLW1 Phosphoadenosine phosphosulfate reductase n=1 Tax=Thioalkalivibrio
           sp. HL-EbGR7 RepID=B8GLW1_THISH
          Length = 378

 Score = 93.7 bits (231), Expect = 7e-18,   Method: Composition-based stats.
 Identities = 53/277 (19%), Positives = 89/277 (32%), Gaps = 63/277 (22%)

Query: 12  LEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYP-GTLPFPLLHV---DTG 66
           L AE+   ++E       P ++ YS GKDS+++LHL        G      ++V   DT 
Sbjct: 14  LVAETKTALKEAYLADGRPWIVAYSGGKDSTLVLHLVYDVLVELGKHAIKPVYVISSDTQ 73

Query: 67  WKFREMYEFRDRT-------AKAYGCELLVHKNPEGVAM---------GINPFVHGSAKH 110
            +   +  +           A+     L+       V           G  P        
Sbjct: 74  VEAPNIVNYVRDVLTAVQKDAERRNLPLICEMVRPAVPETFWSKLIGRGYPPPTRWFRWC 133

Query: 111 TDIMKTEGLKQALNK----YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPE 166
           T  MK +  ++A++K    +G      G+R  E   R K                  R +
Sbjct: 134 TTTMKIKPSRRAIDKITAKHGSVILLLGSRTAESTIRKK--------------GMESRVK 179

Query: 167 LWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENID--------IVPLYLAAERPVLE 218
            + N N       +  + P++ WT+ ++W +++  N          I+ LY  A      
Sbjct: 180 NFRNLNAHHEIPNAFVLAPIATWTDDEVWDFLYTHNPPAWKYPHDQIISLYRQA------ 233

Query: 219 RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLT 255
                  I      +           RF   GCW  T
Sbjct: 234 -------IGGECPVVMDLNTPSCGGGRF---GCWTCT 260


>UniRef50_Q8IR76 CG4407, isoform B n=8 Tax=Drosophila RepID=Q8IR76_DROME
          Length = 294

 Score = 93.3 bits (230), Expect = 9e-18,   Method: Composition-based stats.
 Identities = 53/280 (18%), Positives = 92/280 (32%), Gaps = 62/280 (22%)

Query: 9   LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTL---PFPLLHV 63
           + + + ++     E    +     +  ++ GKD +V+L L  +      +     P+L++
Sbjct: 68  IEERQNKAFAFFAETLQIYGVEELIFCFNGGKDCTVLLDLLMRYLRQENISSGDIPMLYI 127

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
            +G  F E+ EF +R  + Y  +L+ ++                           LK+AL
Sbjct: 128 KSGDSFPEIDEFVERCVRNYRVQLVQYEG-------------------------TLKEAL 162

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
                D             R K      R+     DP  Q   L        +    +R+
Sbjct: 163 THMSSDM-----------PRIKAVFVGSRNT----DPYCQH--LAPMQPTDNDWPPMMRL 205

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL  W+  D+W YI L ++    LY      +  R   +      R D +         
Sbjct: 206 NPLLEWSYHDVWHYIHLNSVPYCSLYDRGYTSIGNRANTVPNPHLRRTDAECECGSNSDA 265

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
           V    LG +             P    E+  +T  ER GR
Sbjct: 266 VCSCDLGGY------------RPAW--ELQDATM-ERAGR 290


>UniRef50_Q04PC4 Phosphoadenylyl-sulfate reductase n=10 Tax=Bacteria
           RepID=Q04PC4_LEPBJ
          Length = 245

 Score = 93.3 bits (230), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 44/269 (16%), Positives = 78/269 (28%), Gaps = 85/269 (31%)

Query: 10  RQLEAESIHI-----IREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
           ++LE +   +     +  +  E+        S+G +  V+ H      +   L   +  +
Sbjct: 4   QELEQKLAPLSLEDSLEWINNEYGETAAFSTSLGLEDQVITH----VIFSRNLKIRIFTL 59

Query: 64  DTGWKFREMYEFRDRTAKAYG-------------CELLVHKNPEGVAMGINPFVHGSAKH 110
           DTG  F E Y+    T  +Y                L+  K P+     ++       + 
Sbjct: 60  DTGRLFNETYDLHKLTNASYNKRIETYFPDTAAVQNLINTKGPDSFYDSVD----NRKEC 115

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
             I K E L +AL   G      G R ++  SR       F                   
Sbjct: 116 CYIRKVEPLNRAL--VGTKLWITGIRSEQSDSRHSLAKVEFDSSR--------------- 158

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
                     ++  PL +W+ + I  +I    +    L+                     
Sbjct: 159 --------NILKYHPLLDWSLERIQDFIDTYRVPTNVLHKKG------------------ 192

Query: 231 IDLQPGEVIKKRMVRFRTLGCWPLTGAVE 259
                          F ++GC P T AV+
Sbjct: 193 ---------------FPSIGCAPCTRAVQ 206


>UniRef50_O33579 Phosphoadenosine phosphosulfate reductase (Fragment) n=15
           Tax=Rhizobiales RepID=CYSH_RHITR
          Length = 180

 Score = 93.3 bits (230), Expect = 1e-17,   Method: Composition-based stats.
 Identities = 37/230 (16%), Positives = 63/230 (27%), Gaps = 82/230 (35%)

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV---------AMGINPFVHGSAKHTDI 113
           + TG  F E  +  D T   Y   +  ++  +             G    V        +
Sbjct: 1   LQTGRLFPETLKLIDETENQYDIRISRYEPEQADIDAYAEKYGLNGFYESVEARHACCGV 60

Query: 114 MKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
            K + L +AL+  G      G RR +  +RA      +                      
Sbjct: 61  RKLKPLARALS--GATIWVTGLRRGQSANRADTPFAEYD--------------------- 97

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
              +   I+V PL++W    I  Y+    + + PL+                        
Sbjct: 98  --PERNLIKVNPLADWDIDVIRAYVADNGVPVNPLHQRG--------------------- 134

Query: 234 QPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                       + ++GC P T A++                   ER GR
Sbjct: 135 ------------YPSIGCEPCTRAIKP---------------GEPERAGR 157


>UniRef50_Q9VYI5 CG4407, isoform A n=4 Tax=melanogaster subgroup RepID=Q9VYI5_DROME
          Length = 322

 Score = 92.5 bits (228), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 53/280 (18%), Positives = 92/280 (32%), Gaps = 62/280 (22%)

Query: 9   LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTL---PFPLLHV 63
           + + + ++     E    +     +  ++ GKD +V+L L  +      +     P+L++
Sbjct: 96  IEERQNKAFAFFAETLQIYGVEELIFCFNGGKDCTVLLDLLMRYLRQENISSGDIPMLYI 155

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
            +G  F E+ EF +R  + Y  +L+ ++                           LK+AL
Sbjct: 156 KSGDSFPEIDEFVERCVRNYRVQLVQYEG-------------------------TLKEAL 190

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
                D             R K      R+     DP  Q   L        +    +R+
Sbjct: 191 THMSSDM-----------PRIKAVFVGSRNT----DPYCQH--LAPMQPTDNDWPPMMRL 233

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL  W+  D+W YI L ++    LY      +  R   +      R D +         
Sbjct: 234 NPLLEWSYHDVWHYIHLNSVPYCSLYDRGYTSIGNRANTVPNPHLRRTDAECECGSNSDA 293

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
           V    LG +             P    E+  +T  ER GR
Sbjct: 294 VCSCDLGGY------------RPAW--ELQDATM-ERAGR 318


>UniRef50_C0SDH1 Phosphoadenosine phosphosulfate reductase n=1 Tax=Paracoccidioides
           brasiliensis Pb03 RepID=C0SDH1_PARBP
          Length = 276

 Score = 92.1 bits (227), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 36/215 (16%), Positives = 62/215 (28%), Gaps = 37/215 (17%)

Query: 46  LARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAY-GCELLVHKNPEG-------VA 97
           +  K   P      L+ +DT   F E     DR  + Y    + V+K  +          
Sbjct: 1   MLSKLQVPRPHRVDLIFLDTLHHFPETLSLLDRVRRHYPSTNIHVYKPADASTPDDFAAQ 60

Query: 98  MGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHR 157
            G   +      +  + K E  ++A  +    A   G RR +   R    I    +    
Sbjct: 61  YGPTLWESNDQLYDWVAKVEPAQRAYRELAVGAVLTGRRRSQGGKRGDLDIIELDEA--- 117

Query: 158 WDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVL 217
                                  I++ PL+NW+   + +Y+    +    L     + V 
Sbjct: 118 ---------------------GLIKINPLANWSFAQVKEYVAANRVPYNELLDRGYKSVG 156

Query: 218 ERDGMLMMIDDN-----RIDLQPGEVIKKRMVRFR 247
           +      + D       R   QP         R R
Sbjct: 157 DWHSTQPVRDTEDERAGRWRGQPKTECGIHNPRSR 191


>UniRef50_Q74M42 NEQ525 n=1 Tax=Nanoarchaeum equitans RepID=Q74M42_NANEQ
          Length = 352

 Score = 92.1 bits (227), Expect = 2e-17,   Method: Composition-based stats.
 Identities = 46/229 (20%), Positives = 83/229 (36%), Gaps = 36/229 (15%)

Query: 8   HLRQLE--AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           ++   E   E+I  I++   ++   V+ +S GKDS+ +  LA+KA     + F L+ VDT
Sbjct: 157 YIDIKEKVNEAIEFIKQ-FKDYE-IVIPFSGGKDSTTVAILAKKA----KVDFDLVFVDT 210

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN- 124
           G +F++  E+ D  +K     + +          +  F +   +     K   L   +  
Sbjct: 211 GLEFKQTLEYIDYISKKIK-PINIVYAGIDKKYKMFGFDYLKRRLCTKDKITTLYNYVRN 269

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            Y       G R  E ++R                           +  +I K E +   
Sbjct: 270 NYENPVLLVGDRLIESEAR--------------------------LFRPRIFKDEFLVAQ 303

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
           P+  ++  D    +  ENI + PLY      V       +   +  I L
Sbjct: 304 PIKFFSYADEQILLEKENIKLNPLYEKGFYRVGCNVCPFLDNYEKSIPL 352


>UniRef50_UPI0001C36A5F hypothetical protein ChatD1_04226 n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C36A5F
          Length = 263

 Score = 91.0 bits (224), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 48/275 (17%), Positives = 85/275 (30%), Gaps = 33/275 (12%)

Query: 32  MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAY---GCELL 88
           M  S GKDS+V+  LA    Y   +PF ++H  T   + E   +  R  K +   G    
Sbjct: 1   MCDSGGKDSNVIKQLA----YLSGVPFEIVHNHTTVDYPETVYYVRREKKRWEKLGISYT 56

Query: 89  VHKNPE--------GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEE 140
           V              +     P +       ++ K        ++        G R +E 
Sbjct: 57  VSYPTYKGKRTTFWELIPLKGPPLRHRRWCCNVPKE-------SQNCNRYIITGVRWEES 109

Query: 141 KSRAKERI-YSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIW 199
             R + R  Y  +             +              + V P+ +WT  ++W++I 
Sbjct: 110 ARRKQNRAAYEIQRTTKDRIKLQNDNDAKRKLMEICQVKGKVIVNPIIDWTTTEVWEFID 169

Query: 200 LENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVE 259
              I   PLY    + +    G  M+ +   ++  P           + +   P +    
Sbjct: 170 RYQIVTNPLYQEGHKRI-GCVGCPMVDNKYELEKNPEFKRMYLNAFQKCVENKPPSRHGW 228

Query: 260 SNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSME 294
              Q L +              GR +D DQ    +
Sbjct: 229 KTGQELYDWWVN---------GGRGMDSDQLCLFD 254


>UniRef50_A6DI54 Possible 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase n=1
           Tax=Lentisphaera araneosa HTCC2155 RepID=A6DI54_9BACT
          Length = 211

 Score = 91.0 bits (224), Expect = 5e-17,   Method: Composition-based stats.
 Identities = 35/215 (16%), Positives = 74/215 (34%), Gaps = 36/215 (16%)

Query: 14  AESIHIIREVAA-EFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A    II++        P++  +     +V+L +A K          ++ VD+G+     
Sbjct: 15  AHPSEIIKKAIEIGGDRPMVSTNFRPLEAVVLDMATKV----KNDVTVVWVDSGYMMPHT 70

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVA-MGINPFVHGSAK------HTDIMKTEGLKQALNK 125
           Y F ++T +     + V+      A  G +  +    +        +I K E  ++AL +
Sbjct: 71  YAFAEKTIEQLKLNIDVYVPKMTAARFGGDAAIPQPEQEEELATFAEIFKLEPFRRALAE 130

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
                 F   R+++ ++R+   I+                               ++  P
Sbjct: 131 VNPSVWFTSLRQEQNQNRSTMDIFDMD------------------------ANGMLKCNP 166

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
           +  WTE D+  Y+    +     Y    +P L  +
Sbjct: 167 VFYWTEADMEAYVQENQLPDEKRYFDPTKPSLSHE 201


>UniRef50_B5YMF1 Predicted protein (Fragment) n=1 Tax=Thalassiosira pseudonana
           CCMP1335 RepID=B5YMF1_THAPS
          Length = 277

 Score = 90.6 bits (223), Expect = 6e-17,   Method: Composition-based stats.
 Identities = 41/226 (18%), Positives = 74/226 (32%), Gaps = 48/226 (21%)

Query: 25  AEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRD---RTAK 81
              +  V + S G    V+LHL  +         P++ +DT   F+E YEF D   +++K
Sbjct: 44  QREAPMVQVTSFGPSGLVVLHLLSQLHMLN--DVPVVTLDTLHLFKESYEFYDTVQQSSK 101

Query: 82  AYGCELLVHKN----------------PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNK 125
             G EL + K                       G   +     ++  + K + L++  N 
Sbjct: 102 FNGMELTITKPIRRDDDGDETEIQTRQEFDEIYGAELWKTEPEQYVQLTKQKPLEKLTNS 161

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
           +       G RR +   R   ++  F                W             ++ P
Sbjct: 162 WHVKMWITGRRRSQGGERTNLKVLEF-------------ARTW-------------KLNP 195

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM-LMMIDDNR 230
           L+  +   +W++I   N+    LY      + +     L    D R
Sbjct: 196 LAYLSYSQVWEHIRHYNLPYNSLYDKGYTSLGDEMTTDLPTGSDER 241


>UniRef50_C5K7J4 FAD synthetase, putative n=1 Tax=Perkinsus marinus ATCC 50983
           RepID=C5K7J4_9ALVE
          Length = 308

 Score = 90.6 bits (223), Expect = 6e-17,   Method: Composition-based stats.
 Identities = 47/240 (19%), Positives = 78/240 (32%), Gaps = 55/240 (22%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGT---LPFPL 60
           +  +RQ  A+S+ II E    +      + ++ GKD +V+LH+    F       +P   
Sbjct: 89  INRVRQQTAKSLSIIAEAYDNYKPEELCLAFNGGKDCTVLLHMVDHVFRQKHSEGVPLRT 148

Query: 61  LHV-----DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMK 115
           L++     DT   F E+  F +   K Y  +++       V +      H   K      
Sbjct: 149 LYIADPKNDT---FEEVESFIEDMQKVYNLDIMRVVGGVKVGLERIKEEHPELK------ 199

Query: 116 TEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQI 175
                         A F G+R             S            +  E W       
Sbjct: 200 --------------AIFMGSR-------------STDPFCGDLTAFAKTTEGW------- 225

Query: 176 NKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
              E +RV P+ +WT  D+W Y+ L  +    LY      +  +   +   D    D   
Sbjct: 226 --PEFMRVNPILDWTYSDVWNYLELYGVKYCKLYGHGYTSIGRKSDTIPNPDLAMRDGDG 283


>UniRef50_B1ZSB4 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=2
           Tax=Verrucomicrobia RepID=B1ZSB4_OPITP
          Length = 219

 Score = 90.2 bits (222), Expect = 8e-17,   Method: Composition-based stats.
 Identities = 31/200 (15%), Positives = 68/200 (34%), Gaps = 36/200 (18%)

Query: 14  AESIHIIREVAAEFSNPVMLYS-IGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
              + I+R   A+ +   ++ +      +V+LHLA +         P+L VD G+     
Sbjct: 16  QSPLEIVRWAIAKANGRAIVSTNFRPYEAVVLHLATQV----QPDIPVLWVDHGYNRAAT 71

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVAMGI-------NPFVHGSAKH-TDIMKTEGLKQALN 124
           Y   ++     G  L  +      A           P    + K  + +MK E  ++ + 
Sbjct: 72  YRHAEQLRAQLGLNLKAYLPRISPAHRDAIHGEIPTPADEDALKQFSAVMKLEPFQRGMK 131

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           +          R+ +  +RA+  I S    F                        +++V 
Sbjct: 132 ELAPTVWITALRKVQNPNRAELDIVSPDGNFG-----------------------TLKVS 168

Query: 185 PLSNWTEQDIWQYIWLENID 204
           P+ + ++ ++  Y+    + 
Sbjct: 169 PVFHSSDAEMEAYLTKHGLP 188


>UniRef50_Q1VVA9 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS
           reductase)/FAD synthetase and related enzyme n=1
           Tax=Psychroflexus torquis ATCC 700755 RepID=Q1VVA9_9FLAO
          Length = 229

 Score = 90.2 bits (222), Expect = 8e-17,   Method: Composition-based stats.
 Identities = 34/251 (13%), Positives = 72/251 (28%), Gaps = 69/251 (27%)

Query: 17  IHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           I  I+ +  +F     ++  S    S+ +L    K F        +  +DTG+ F E  +
Sbjct: 28  IDRIKALYEDFDESEIMLTSSFAATSAFLL----KLFSEVNTDQIIYFIDTGYHFDETIK 83

Query: 75  FRDRTAKAYGCELLVHKN---PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAA 131
           ++ + ++ Y   +   K              +         I K + L+  + K  +   
Sbjct: 84  YKKQLSETYNLNVKSVKALAHEHEFTTKDKTWSENPDLCCSINKVKPLE--VIKNKYTVW 141

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
             G    +   R    I+  R                         G+ ++ +PL + ++
Sbjct: 142 VSGLMEWQSDHRNSLDIFEQR-------------------------GDILKFYPLVDVSK 176

Query: 192 QDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGC 251
           Q    +I   ++   PL                                     + ++GC
Sbjct: 177 QQRDDFIKAHDLPFHPL---------------------------------VSKGYNSIGC 203

Query: 252 WPLTGAVESNA 262
              T   E  +
Sbjct: 204 QHCTVPGEDRS 214


>UniRef50_Q4FSU0 Phosphoadenylylsulfate reductase (Thioredoxin) n=15 Tax=Bacteria
           RepID=Q4FSU0_PSYA2
          Length = 212

 Score = 90.2 bits (222), Expect = 9e-17,   Method: Composition-based stats.
 Identities = 35/203 (17%), Positives = 75/203 (36%), Gaps = 36/203 (17%)

Query: 10  RQLEAESIH-IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           + L+ +S   I+    ++  NP++  +     S +LHL  K          +L VD+G+ 
Sbjct: 15  QDLQGKSPEQIVEWALSQAKNPIITTNFRPYESAILHLVAKQ----RPDITVLWVDSGYN 70

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGS-------AKHTDIMKTEGLKQ 121
               Y+F ++  +     ++ +   +  A                  + TD +K E  ++
Sbjct: 71  TDATYQFANKVIRDLNLNVITYIPKQTAAHRDVTMEGIPGIDNPLHDEFTDQVKLEPFRR 130

Query: 122 ALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
           AL++   D  F   R+D+ + R    + S                        ++K   +
Sbjct: 131 ALDELKPDVWFNAIRKDQTEFRQGLDVLS------------------------LSKDGVL 166

Query: 182 RVFPLSNWTEQDIWQYIWLENID 204
           +V PL   ++ D+  Y+    + 
Sbjct: 167 KVAPLFEKSDADLDVYLDEHGLP 189


>UniRef50_Q8GA37 Z1203 protein n=70 Tax=Bacteria RepID=Q8GA37_ECOLX
          Length = 410

 Score = 89.8 bits (221), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 44/243 (18%), Positives = 72/243 (29%), Gaps = 42/243 (17%)

Query: 15  ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
            +IH I  +   FS+  + +S GKDS+V+LHLA          F +L +D   +++   E
Sbjct: 19  AAIHRIEWLFETFSSVCLSFSGGKDSTVLLHLAADVARRKKRRFSVLFIDWEAQYQCTIE 78

Query: 75  FRDRTAKAYG----------CELLVHKNPEGVAMGINPFV-------HGSAKHTDIMKTE 117
              +  + Y             L               +        H        M   
Sbjct: 79  HVQKMREMYRDVTDTFYWVALPLTTVNGVSQFQPEWICWEPDVTWVRHPPEYAITDMAYF 138

Query: 118 GLKQALNKYG-----FDAAF----------GGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
              +    +      F + F           G R DE  +R                 + 
Sbjct: 139 PFYRYAMTFEEFVPAFSSWFAGNRCGVAILTGVRADESLNR----------FMGLVSQRK 188

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
            R      +     +G    ++PL +W  +DIW Y         PLY    R  +    M
Sbjct: 189 LRYADDKPWTTASPEGFYYTMYPLYDWKARDIWIYNARTRAIYNPLYDLMYRAGVPLRNM 248

Query: 223 LMM 225
            + 
Sbjct: 249 RVC 251


>UniRef50_A9FNW8 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=1 Tax=Sorangium
           cellulosum 'So ce 56' RepID=A9FNW8_SORC5
          Length = 255

 Score = 89.1 bits (219), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 51/279 (18%), Positives = 89/279 (31%), Gaps = 86/279 (30%)

Query: 14  AESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A  + ++R V   F     ++ S+ +  + + H+A +A     L F ++ VDTG    E 
Sbjct: 18  APPVELLRFVRESFGPRAAIMSSMQRAGTALCHMADRA----GLSFDVVFVDTGVLHAET 73

Query: 73  YEFRDRTAKAY-GCELLVHKNPEGVAMG------INPFVHGSAKHTDIMKTEGLKQALNK 125
              RD  A+ +    ++        A        +     G  +  D+ K+  L  A+  
Sbjct: 74  LATRDELARTHPNLRVVTLSPERSFAQQTREEGLLYLSKEGQERCCDLRKSAPLS-AIR- 131

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
             +DA     RR E  +RAK   +                              ++RV P
Sbjct: 132 GRYDALVAALRRGEGGARAKVAPFGLD-----------------------PANNTLRVHP 168

Query: 186 LSNWTEQDIWQYIWLE-NIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
            ++ T +++  Y     +    PL+                                  +
Sbjct: 169 FASLTGEELDAYFAAHEDALENPLH---------------------------------GM 195

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
            FRT+GC+P T  V  +                 ER GR
Sbjct: 196 GFRTIGCFPCTTPVLPD---------------EPERAGR 219


>UniRef50_B6YXY8 3'-phosphoadenosine 5'-phosphosulfate reductase n=7
           Tax=Thermococcaceae RepID=B6YXY8_THEON
          Length = 425

 Score = 88.3 bits (217), Expect = 3e-16,   Method: Composition-based stats.
 Identities = 34/211 (16%), Positives = 71/211 (33%), Gaps = 28/211 (13%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           ++   ++      S   +R+   ++   ++ +S GKDS+  L LA + F         ++
Sbjct: 211 ELNQDYIDAFAEASKAFLRQ-FEDYD-IIVPWSGGKDSTATLILASEVFK----DVTAIY 264

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
           V   ++     E+ ++ A+     L+    P  +     P      +     K E L +A
Sbjct: 265 VRMEYEMLLTDEYVEKLARKLKINLVRVDVPMPLDEFGMPIHR--NRWCTRQKVEALYKA 322

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
             ++       G R  E   R  +     R                         G+ + 
Sbjct: 323 AGEFERPLLVVGDRDGESARRRLKPPVIERKNDIL--------------------GKFLE 362

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAE 213
           V P+  W+   +  +I +   ++ PLY    
Sbjct: 363 VMPIKFWSGMMVQLFIIMRGFELHPLYYEGF 393


>UniRef50_A2DE77 Phosphoadenosine phosphosulfate reductase family protein n=1
           Tax=Trichomonas vaginalis RepID=A2DE77_TRIVA
          Length = 227

 Score = 87.1 bits (214), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 39/207 (18%), Positives = 75/207 (36%), Gaps = 47/207 (22%)

Query: 14  AESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPL--LHVDTGWKFR 70
           A +  +++   A+      + ++ GKDSSV+L L R+      +  P+    +     F 
Sbjct: 24  AITSKVLKLAYADHGPEIGLCFNGGKDSSVVLDLVRRFHESAKISTPVRPFFIKEKNDFP 83

Query: 71  EMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDA 130
           E+ EF  +T +  G  +   ++                          +++ + +    +
Sbjct: 84  EITEFVKQTEERIGVTIRKVQSDSIKN--------------------AIEKIVEEDRIYS 123

Query: 131 AFGGARR-DEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
            F G R+ D   S  KE   +  D  H                       ++R+FP+ NW
Sbjct: 124 FFLGQRKTDPNCSNIKEFNLTSDDWVH-----------------------AMRIFPILNW 160

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPV 216
             +DIW+YI    + +  LY      +
Sbjct: 161 AYKDIWEYIDALELPVCSLYSKGYTSI 187


>UniRef50_B1YE28 Phosphoadenosine phosphosulfate reductase n=1 Tax=Thermoproteus
           neutrophilus V24Sta RepID=B1YE28_THENV
          Length = 392

 Score = 87.1 bits (214), Expect = 7e-16,   Method: Composition-based stats.
 Identities = 43/224 (19%), Positives = 80/224 (35%), Gaps = 33/224 (14%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSS---VMLHLARKAFYPGTLPFPLLHVDT 65
           L  L +E+  +  E A ++   V+ +S GKDS+   ++ +   K          LLH DT
Sbjct: 3   LDLLLSEAFEVFEEAALKYRTFVIAFSGGKDSTAAAILFYKWAKRRNGVKNRVVLLHNDT 62

Query: 66  GWKFREMYEFRDRTAK-------AYGCELLV---HKNPEGVAMGINPFVHGSA------K 109
             +  EM  + D  A+         G ++ V   + +P              A       
Sbjct: 63  LSEIPEMELWVDHFARQFKAKMRELGTDVHVRYAYPHPTETWYWRVLVRGYPAPTFNFRW 122

Query: 110 HTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWH 169
             D++K E  ++ L ++       G+R +E  +RAK     F                  
Sbjct: 123 CVDMLKIEPTERELRRHANHVLVVGSRDEESGARAKSMKTRFGTCSGGG----------S 172

Query: 170 NYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN----IDIVPLY 209
                 + G+  ++ P+  WT   +W ++  +       +  LY
Sbjct: 173 CLGAYFSHGDIPKIAPIRFWTYDMVWSFLRAQKDFDVQPLEELY 216


>UniRef50_D0TA45 Putative uncharacterized protein n=1 Tax=Bacteroides sp. 2_1_33B
           RepID=D0TA45_9BACE
          Length = 309

 Score = 86.8 bits (213), Expect = 9e-16,   Method: Composition-based stats.
 Identities = 39/218 (17%), Positives = 77/218 (35%), Gaps = 30/218 (13%)

Query: 10  RQLEAESIHIIREVAAEFSN----PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
            ++E ++I  I++ A           + +S GKDS V   L +++           H + 
Sbjct: 15  EEIEQQAIERIQKFAKIAKTMGLEVSLGFSGGKDSQVCYDLCKRSGINFKP-----HFNH 69

Query: 66  GWKFREMYEFRD---------RTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
            ++      F           R  K  G    +  N +G+          +A   +  K 
Sbjct: 70  CFESNITIRFIRDNYPNVIFRRVVKE-GFIRNIRVNHKGL-----LPTVQTAYCCEDYKH 123

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
                   K     +  G R+ E   R    ++  R++      K    + + +    I 
Sbjct: 124 NP------KSVDSCSIVGVRKAESSKRKARTVFEARNKTIMKRNKALFNDYFDDRCKSIG 177

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAER 214
               I++ P+ +W ++D+W YI   N+ + P Y  + R
Sbjct: 178 SAGLIQLKPIVDWEDEDVWDYIKRYNLPVNPEYKTSNR 215


>UniRef50_A3XKN2 Possible 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase n=1
           Tax=Leeuwenhoekiella blandensis MED217
           RepID=A3XKN2_9FLAO
          Length = 209

 Score = 86.4 bits (212), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 41/200 (20%), Positives = 75/200 (37%), Gaps = 30/200 (15%)

Query: 18  HIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRD 77
           HIIR + +    P++  + G  S+ ++H    A        PL+  DTG+  ++   F  
Sbjct: 27  HIIRFILSSSKRPILTSNFGPYSASLIH----AVSKQRNGIPLIWCDTGFNTQQTLNFAK 82

Query: 78  RTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHT--DIMKTEGLKQALNKYGFDAAFGGA 135
           R  ++   +L  +K  +  +    P   G A     + +K E  K+AL ++  D  F   
Sbjct: 83  RIEQSLPIDLKRYKPSKKYSESELPSESGEAFQNFVNDVKLEPFKRALAEHNPDVWFTNI 142

Query: 136 RRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIW 195
           RR +   R    I S                        +     ++V P   WT+ ++ 
Sbjct: 143 RRGQTAYRDTLDILS------------------------LTSDGILKVSPFYFWTDTELR 178

Query: 196 QYIWLENIDIVPLYLAAERP 215
            Y+   N+    +Y    +P
Sbjct: 179 GYLSQFNLPNEFIYFDPTKP 198


>UniRef50_A3RYW5 Co-activator of prophage gene expression IbrA n=10
           Tax=Proteobacteria RepID=A3RYW5_RALSO
          Length = 416

 Score = 86.4 bits (212), Expect = 1e-15,   Method: Composition-based stats.
 Identities = 48/269 (17%), Positives = 85/269 (31%), Gaps = 38/269 (14%)

Query: 15  ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYP-GTLPFPLLHVDTGWKFREMY 73
            +   +R V A+F+   + +S GKDSSV LHLA +     G  P     +D   ++R   
Sbjct: 13  AAKARLRLVFAQFAQVCVAFSGGKDSSVTLHLALEVAREMGRGPVHAFFIDLEGQYRATI 72

Query: 74  EFRDRTAKAYG-------CELLVHKNPEGVAMGINPFVHGSAK----------------- 109
           +        +          + +      +      +  G                    
Sbjct: 73  DHVTEMLSRHDVRPWWVCLPINLRNASSALEPFWCAWEPGREADWIRPLPTHPSVISDPD 132

Query: 110 ----HTDIMKTEGLKQALNKY----GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPK 161
               +   M+ E    A N +       A   G R DE  +R          +   W P 
Sbjct: 133 HFPFYRFRMEFEAFVPAFNAWLARDTPTAILVGIRSDESLNRYLAVKRRATIKKCAWTPP 192

Query: 162 N-QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
              RP  W   +    +  ++  FP+ +W  +D+W+Y+    +    LY    R  +   
Sbjct: 193 GADRPIAWSARD--HARSRAVTFFPIYDWRFEDLWRYVAERGLAYNRLYDQMYRAGVACS 250

Query: 221 GMLMMID--DNRIDLQPGEVIKKRMVRFR 247
            M +     D++          +    FR
Sbjct: 251 QMRICQPYGDDQRKGLDLYHRIEPGTWFR 279


>UniRef50_A6Q5M8 Phosphoadenosine phosphosulfate reductase n=1 Tax=Nitratiruptor sp.
           SB155-2 RepID=A6Q5M8_NITSB
          Length = 439

 Score = 85.6 bits (210), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 60/326 (18%), Positives = 109/326 (33%), Gaps = 62/326 (19%)

Query: 12  LEAESIHIIREVAAEF---SNP-VMLYSIGKDSSVMLHLARKAF----YPGTLPFPLLHV 63
           LE +   + +++  EF   + P V+ +S GKDS+ +L L  +        G      +++
Sbjct: 2   LEEKVKAVKQKLREEFLIDNRPWVITFSGGKDSTAVLQLTIEMLLDLKEEGYKDLKKVYI 61

Query: 64  ---DTGWKFR--EMY---------EFRDRTAKAYGCELLVHKNPEG-------VAMGINP 102
              DT  +    E Y         +F D++      E+ V K           +  G   
Sbjct: 62  VSSDTKVEMPIIEEYLDNKLQAIQDFIDKSGLNLNIEIKVLKPKVSETFWTLLLGKGYPS 121

Query: 103 FVHGSAKHTDIMKTEG----LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRW 158
                   TD +K +     LK    K+       G R  E ++RA+      R   HR 
Sbjct: 122 PNQNFRWCTDRLKIKPATYFLKNLAYKHKSIIMLLGVRSAESQNRAQS--IEKRVLNHRG 179

Query: 159 DPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE 218
             K+                 +    P+ +W+  D+W Y+                  + 
Sbjct: 180 FSKHDSI------------PNAFVFSPIRDWSNADVWTYLSKNQAPW------GSHKDMM 221

Query: 219 RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEII---EEMLVS 275
           +       + +       E       RF   GCW  T  V S  +++  ++   E++ ++
Sbjct: 222 KLYDKGSGEADCNIALNPEAPSCGKTRF---GCWVCT--VVSKDKSMENMLRNEEDLWMA 276

Query: 276 TTSE-RQGRVIDRDQAGSMELKKRQG 300
              E R    I R      + ++R G
Sbjct: 277 PLHEFRNKLEIYRYDHSKRQNRRRNG 302


>UniRef50_A0DD33 Chromosome undetermined scaffold_46, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0DD33_PARTE
          Length = 205

 Score = 85.6 bits (210), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 47/251 (18%), Positives = 85/251 (33%), Gaps = 51/251 (20%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAA--EFSNPVMLYSIGKDSSVMLHLARKAFYPGTLP- 57
           MD         L  E+I  + ++    +F    + ++ GKD++V+L+LA+ A     +  
Sbjct: 1   MDNQNSQPSTILFQEAIDFLVKIFQIFKFPQIKICFNGGKDATVVLYLAKMALEKLQISR 60

Query: 58  -FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
               ++      F E+ EF ++  KA   +++                            
Sbjct: 61  EIECIYFKEKQPFPEIIEFMEQQKKALNLQIVE---------------------CKGCVK 99

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           E L+   N+    A   G RR                     DP  +   L    +   N
Sbjct: 100 ENLQ---NQVQLQAVIMGTRR--------------------SDPHGKTLNLISITDN--N 134

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
               +R+ P+  W    IW++I   NI    LY      + E  G      + +I ++P 
Sbjct: 135 YPSLLRINPILEWNYSQIWEFIRTFNIPYCSLYDQGYMCLGE-VGKTQPDKNYKIGMKPW 193

Query: 237 EVIKKRMVRFR 247
           E   +   + R
Sbjct: 194 EFDPQFERQNR 204


>UniRef50_UPI000186D96A molybdopterin- binding protein, putative n=1 Tax=Pediculus humanus
           corporis RepID=UPI000186D96A
          Length = 501

 Score = 85.2 bits (209), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 39/215 (18%), Positives = 74/215 (34%), Gaps = 56/215 (26%)

Query: 11  QLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPL--LHVDTG 66
            L   S+ +I     ++ +    + ++ GKD +V+LHL           F +  +++  G
Sbjct: 296 NLVRNSLKVIETAFEKYKSDEIYLSFNGGKDCTVLLHLIWTVCKIQNYTFKINCVYIKNG 355

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
             F E+ +F   T   Y   +++                             +K+AL + 
Sbjct: 356 SVFPEVDKFVTDTVNKYKLNVVIA-------------------------FGPIKEALTEL 390

Query: 127 -----GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
                   A F G RR +  S   E +  F++    W P                    +
Sbjct: 391 HKRIPEIKAIFMGTRRTDPHS---ENLQEFQECDKDWPP-------------------LM 428

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
           RV P+ +W+  DIW ++ +  +    LY      +
Sbjct: 429 RVSPILDWSYHDIWDFLRILPVPYCTLYNEGYTSI 463


>UniRef50_B3RLV6 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
           adhaerens RepID=B3RLV6_TRIAD
          Length = 485

 Score = 85.2 bits (209), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 48/282 (17%), Positives = 86/282 (30%), Gaps = 68/282 (24%)

Query: 14  AESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHL----ARKAFYPGTLPFPLLHVDTGW 67
            E+  I+     ++   N  + ++ GKD +V+LH+     +  F         ++  +  
Sbjct: 261 QEAFQIVDRALEQYGLNNIAIAFNGGKDCTVILHIFYCFVKSRFPEQIPKIKAIYTKSED 320

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
            F EM +F  +    Y  ++    +                          +K AL +Y 
Sbjct: 321 IFTEMDQFVSKCVDRYNLDITTISSD-------------------------MKSALEEYS 355

Query: 128 F-----DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
                  A   G RR                  ++  P       W          E +R
Sbjct: 356 IREPTVKAVIMGTRR-------------ADPYSNQLTPFCMTDGDW---------PEYLR 393

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           V P+ +W+  +IWQ++   +I    LY      +       +        L+      + 
Sbjct: 394 VHPILDWSYSEIWQFLRHSSIPYCSLYDLGYTSL-----GGIHNTKPNSSLRRTRDEIET 448

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRV 284
            ++  TL   PL             + EE L     ER GR 
Sbjct: 449 FIKEGTLEAEPLLQFDGYYYLPAYFLTEEQL-----ERAGRS 485


>UniRef50_A0YCE4 Possible 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase n=3
           Tax=Bacteria RepID=A0YCE4_9GAMM
          Length = 214

 Score = 85.2 bits (209), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 39/229 (17%), Positives = 76/229 (33%), Gaps = 38/229 (16%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           MD   L    + EA  + I+R       + +   S   +++ MLH             P+
Sbjct: 8   MDLAALNQTLKNEAP-VDIVRWATTLGKSIIATTSFAPNAAAMLH----VITAADAAIPV 62

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNP------EGVAMGINPFVHGSAKH---T 111
           + +D+G+   + Y   +   +     + ++           +  GI         H   T
Sbjct: 63  VWIDSGYNVPDTYRAAEIIMERLKPNMQIYIPQWTAERRSAIMGGIPHPDDDPDVHEEFT 122

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
             +K E  ++AL+    +    G R++E + R    I S  +R                 
Sbjct: 123 RQVKLEPFQKALDDLQPEVWVSGIRQEETEFRKSLDILSIDNR----------------- 165

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
                    ++V P   WTE+ +  Y+ L  +     Y    +    R+
Sbjct: 166 -------GILKVAPFFYWTEEQVVGYMALNKLPSCKHYFDPTKVEDGRE 207


>UniRef50_C0EBX2 Putative uncharacterized protein n=2 Tax=Clostridium
           RepID=C0EBX2_9CLOT
          Length = 321

 Score = 85.2 bits (209), Expect = 3e-15,   Method: Composition-based stats.
 Identities = 50/250 (20%), Positives = 84/250 (33%), Gaps = 75/250 (30%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           L +    +   I E    +   V + +S GKDS+V+L LAR+ +       P ++VDTG 
Sbjct: 16  LERKIRVTQTRIMEWYMRYDGQVFISFSGGKDSTVLLDLARRVY----PDIPAVYVDTGL 71

Query: 68  KFREMYEFRD---------------RTAKAYGCELLVHK--------------------- 91
           ++ E+ +F                 +  + YG  ++  +                     
Sbjct: 72  EYPELRDFVKTKDNVTWLRPRYPFTQILEKYGYPIISKEVSDVINGARKGQPYRLARLNG 131

Query: 92  ------------NPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDE 139
                       N E     ++     SA+    MK   L +   + G      G    E
Sbjct: 132 ELLDKNGKKSIYNCENYKYLLDAPFKISARCCYHMKKAPLNKFERQSGRHP-ITGVLACE 190

Query: 140 EKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIW 199
            K R +  I     +F     + QRP                   PL+ W E+DI +Y+ 
Sbjct: 191 SKLREQSWI-----KFGCNGFERQRPLS----------------QPLAFWLEEDILRYLK 229

Query: 200 LENIDIVPLY 209
           +  I   P+Y
Sbjct: 230 MTGIPYAPIY 239


>UniRef50_A6L476 Putative sulfate adenylate transferase, subunit 2 n=4
           Tax=Bacteroides RepID=A6L476_BACV8
          Length = 289

 Score = 83.7 bits (205), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 38/231 (16%), Positives = 72/231 (31%), Gaps = 13/231 (5%)

Query: 29  NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELL 88
             ++ +S GKDS   L  A K +  G      +  DTGW+  + Y+      K  G  + 
Sbjct: 2   KIIVSFSGGKDSQACLIQAAKQY--GADKIEAVFCDTGWEHPDTYQHITDVCKQMGVRIT 59

Query: 89  VHKNP---EGVAMGINPFVHGSAKHTDI-MKTEGLKQALNKYGFDAAFG-GARRDEEKSR 143
             K       +      F     +   + +K + +   +           G R  E   R
Sbjct: 60  TLKPEFNFIEICKKYRRFPDPIRRFCTVDLKVKPMVDYILSLQESCIIIEGIRASESYKR 119

Query: 144 A--KERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLE 201
           +  +E    F+  F   +          +        ++  +  +  WT Q++   I   
Sbjct: 120 SSMEEECMYFKSYFTPNEKGKFASYRKKDVKEWCGMYDASVLRSVFRWTAQEVIDCILNA 179

Query: 202 NIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCW 252
                PLY         R G    +  N  +++     K+   R + +   
Sbjct: 180 GQKPNPLYSRG----FSRVGCFPCVMSNLQNIKMLLNDKEMCSRLKNVEDE 226


>UniRef50_Q4JBE9 Conserved Archaeal protein n=1 Tax=Sulfolobus acidocaldarius
           RepID=Q4JBE9_SULAC
          Length = 308

 Score = 83.3 bits (204), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 56/299 (18%), Positives = 100/299 (33%), Gaps = 46/299 (15%)

Query: 15  ESIHIIREVAAEFSNP--VMLYSIGKDSSVMLHLARKAFYPGTL--PFPLLHVDTGWKFR 70
           E+I +I   + E SN    + +S GKDS+ +L L  KA   G +     +++ DT  +  
Sbjct: 7   EAIELIINASEELSNLPWELGFSGGKDSTTVLSLTLKAMERGAMIKTLYVVYADTLLEHP 66

Query: 71  ----EMYEFRDRTAKAYGCELLVHKNPEG-----VAMGINPFVHGSAKHTDIMKTEGLKQ 121
               E  +  +        + +     E      V  G     H      + +K   +K+
Sbjct: 67  ILRKEALDALESLKVYPNVKPIRLTPIEDFISMMVERGYPAPSHRFRWCMERLKLRPMKR 126

Query: 122 ALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
            + + G      G R  E   RAK+  Y                   +  + +I +  + 
Sbjct: 127 FMEQLGKFVQLSGVRMTESSERAKQTAY-------------------NGKHEKIIRLGNP 167

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
            + P+ +WT +D+++Y+  E            R        L+ + + + D         
Sbjct: 168 IIMPILDWTTEDVFRYLRSER-----------RWDGREFDYLLNLYEVKEDNDGCGCALT 216

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
             VRF   GCW  T            + E   +     R  R    D+ G       +G
Sbjct: 217 TDVRF---GCWVCTVVKNDKMPVSDTLKEARKMIMDISRDLRYRIIDKNGKPRSLNEEG 272


>UniRef50_B0D4U7 Predicted protein n=2 Tax=Agaricales RepID=B0D4U7_LACBS
          Length = 320

 Score = 83.3 bits (204), Expect = 9e-15,   Method: Composition-based stats.
 Identities = 50/288 (17%), Positives = 86/288 (29%), Gaps = 49/288 (17%)

Query: 12  LEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFY------PGTLPFPLLHV 63
           L  E++ +I             + ++ GKD +V+LHL   A            P   +++
Sbjct: 24  LVKEALEVIDHALDTHGQDGLSISFNGGKDCTVLLHLYAGAIARRLQLSEEMKPIHSIYI 83

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEG---VAMGINP-FVHGSAKHTDIMKTEGL 119
                F  +  F  +T K Y  +L   ++        +   P           I   EG+
Sbjct: 84  PVPSPFPSLEAFISKTEKTYNLDLFSCRSALSQVDPTLTTGPGEPGAPKAAGKIRPGEGM 143

Query: 120 KQALNKY-----GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
             AL  Y        A   G RR                             L H     
Sbjct: 144 LHALAMYKERFPQVTAILIGTRR----------------------TDPHGATLSHRNMTD 181

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                  RV P+ NW+  D+W+++    +    LY      +               + +
Sbjct: 182 PGWPCFERVNPIINWSYADVWKFLRQLEVPYCDLYDQGYTSLGSTYNTFPNPALLVPEQK 241

Query: 235 P---GEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE 279
           P   G+      V   +      T +  S +  +P +  E   S+T+E
Sbjct: 242 PLVEGKTPLSTPVSPES-----CTSSTPSRSNGVPPV--EPSRSSTTE 282


>UniRef50_C4WUE8 ACYPI004304 protein n=2 Tax=Acyrthosiphon pisum RepID=C4WUE8_ACYPI
          Length = 321

 Score = 83.3 bits (204), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 45/232 (19%), Positives = 78/232 (33%), Gaps = 48/232 (20%)

Query: 15  ESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTL--PFPLLHVDTGWKFR 70
           E+I +I+E   +F   N  + ++ GKD  V+L+L +       L      +   +  +F 
Sbjct: 117 EAIQVIKESIDKFTLENIFLSFNGGKDCVVLLYLFQAVLEELKLNGQIKAVFFQSDDQFS 176

Query: 71  EMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY-GFD 129
           E  ++   T   +  +L V K                      +K  GL   L +   F 
Sbjct: 177 EEEDYVQSTVNRFNLDLTVIKGE--------------------LK-SGLNDFLKENPHFC 215

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
           A+  G R+ +  S  K + +   D                           +RV PL +W
Sbjct: 216 ASIIGTRQSDTGS-TKLQFFQKTDP---------------------GWPILVRVQPLLHW 253

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
              +IW ++   +I    LY      +  +       +   ID   GEV   
Sbjct: 254 NYDNIWSFLRQFSIPYCSLYDKGYTSLGNKSKSHPNPNLKYIDENTGEVKYW 305


>UniRef50_D1IAI6 Whole genome shotgun sequence of line PN40024,
           scaffold_7.assembly12x (Fragment) n=3 Tax=Magnoliophyta
           RepID=D1IAI6_VITVI
          Length = 514

 Score = 83.3 bits (204), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 41/227 (18%), Positives = 74/227 (32%), Gaps = 61/227 (26%)

Query: 8   HLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARK--------------AF 51
            L+     +I+++R   A +      + ++ GKDS+V+LHL R                 
Sbjct: 14  RLKTKYNNAIYVVRRALALYSVEEVALSFNGGKDSTVLLHLLRAGYFLHKREQSHSNGVL 73

Query: 52  YPGTLPFPL--LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAK 109
               + FP+  ++ ++   F E+  F   TA  YG ++ + +                  
Sbjct: 74  TDHEVAFPIRTIYFESPSAFPEINSFTYETATTYGLQMDIIRLDF--------------- 118

Query: 110 HTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWH 169
                   GL+  L      A F G R                      DP     E + 
Sbjct: 119 ------KSGLEALLEAKPIRAIFLGVR--------------------IGDPTAVGQEQFS 152

Query: 170 NYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
                      +RV P+ +W+ +D+W ++    I    LY      +
Sbjct: 153 --PSSPGWPPFMRVNPILDWSYRDVWAFLLACKIPYCSLYDRGYTSI 197


>UniRef50_Q8MZ99 AT21573p n=9 Tax=Drosophila RepID=Q8MZ99_DROME
          Length = 254

 Score = 82.9 bits (203), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 41/219 (18%), Positives = 79/219 (36%), Gaps = 47/219 (21%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVML--YSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
             LR     +  +I+     +    M+  ++ GKD +V+L +  +   P  +P   ++V 
Sbjct: 33  DQLRDKLEHTEEVIKRAMTLYKPNEMMLSFNGGKDCTVLLDILARMTPPS-MPLGAVYVK 91

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           +   F E+ +F D + + YG +L                     ++  ++K    +Q + 
Sbjct: 92  SANPFEELEKFVDDSVQRYGLQL--------------------RRYEGVLKV-AFEQLIA 130

Query: 125 K-YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           +     A F G RR + +S     +Y      + W                      +R+
Sbjct: 131 EDSQVKAIFLGCRRSDPES---CNLYELEPTNNGW-------------------PAMMRI 168

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
           FPL  W+  DIW Y+    +    LY      + +R   
Sbjct: 169 FPLLEWSYHDIWNYLRSNYLPYCCLYDQGYTSLGDRSST 207


>UniRef50_A8IWB7 FAD synthetase n=1 Tax=Chlamydomonas reinhardtii RepID=A8IWB7_CHLRE
          Length = 578

 Score = 81.4 bits (199), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 47/260 (18%), Positives = 78/260 (30%), Gaps = 52/260 (20%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYP----- 53
           ++ I    + +   ++I  +R   A +        ++ GKDS+V+LHL R A        
Sbjct: 8   LESIPDPVVLEKSKKAIACLRRTCALYPLEKIAFSFNGGKDSTVLLHLLRAAVAQQEAAK 67

Query: 54  ---GTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKH 110
              G       +      F E+  F +   KAYG ++    + +    G           
Sbjct: 68  GSAGLGGMLSFYFRQKDDFAEVKAFVEGADKAYGLDVEYL-SEQDFKKG----------- 115

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
                   L + L + G  A   G RR                     D      E W  
Sbjct: 116 --------LCEYLERTGVMAIVLGTRR-------------GDPNAGGQDVFCPSSEGWPA 154

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
           +         +RV P+ +WT  D+W ++    +    LY      +      L      R
Sbjct: 155 F---------MRVNPILDWTYHDVWVFLRATRVAYCSLYDHGYTSLGGVGNTLPNNTLRR 205

Query: 231 IDLQPGEVIKKRMVRFRTLG 250
            D            R   +G
Sbjct: 206 PDGSYEPAYHLADGRLERVG 225


>UniRef50_Q4DC85 Phosphoadenosine phosphosulfate reductase-like protein, putative
           n=4 Tax=Trypanosoma RepID=Q4DC85_TRYCR
          Length = 364

 Score = 81.4 bits (199), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 53/238 (22%), Positives = 80/238 (33%), Gaps = 48/238 (20%)

Query: 2   DQIRLTH-LRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTL-P 57
           D  +L    + L   SI +IREVA  F      + ++ GKDS VM+ L   A  P  L  
Sbjct: 146 DDPKLERPAQSLVKSSIDMIREVAGRFKPEEIGVAFNGGKDSVVMMDLLECALGPEMLSR 205

Query: 58  FPLLHVDTG--WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMK 115
           F +  +      +F E+  FR+   + +G          GV   ++  +           
Sbjct: 206 FCVFTLGASGREEFGEVVAFREAYLENHGLT--------GVKTDVSLSMKD--------- 248

Query: 116 TEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQI 175
             GL Q     G    F G R  +   + K    S       W                 
Sbjct: 249 --GLAQLKESKGIALVFMGTRSSDSVHQKK----SVEPTTAGW----------------- 285

Query: 176 NKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
              E +R  P+ +W  +DIW YI   ++    LY      +  R      +   R D 
Sbjct: 286 --PEMLRACPVFHWGYEDIWGYILAYSLPFCILYKMGYTSLGLRGATAPNVLLRRGDG 341


>UniRef50_B7J801 Conserved domain protein n=1 Tax=Acidithiobacillus ferrooxidans
           ATCC 23270 RepID=B7J801_ACIF2
          Length = 574

 Score = 80.6 bits (197), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 49/262 (18%), Positives = 81/262 (30%), Gaps = 52/262 (19%)

Query: 27  FSNPV-MLYSIGKDSSVMLHLARKAFYPG-------TLPFPLLHVDTGWKFREMYEFR-- 76
              PV + +S GKDSSV+L+L  +A             P  + H DTG +  E+  +   
Sbjct: 14  CDRPVSVAWSGGKDSSVVLNLTMQAAKAVLESGQTIAAPILVTHGDTGIENPEIRAYAST 73

Query: 77  -----DRTAKAYGCELLVHKNPEGVAMGINP----------FVHGSAKHTDIMKTEGLKQ 121
                 R A+ +   L VH     +                F   +   T  +K   +++
Sbjct: 74  EIGRLRRYAERHRIPLAVHVATPNLTESWPLRVIGGRALPSFPGMNHDCTTDLKIHPMQR 133

Query: 122 A---LNKYGFDA---AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQI 175
               L      A      G R +E   RA   +         W                +
Sbjct: 134 LRKRLQNPKTAASLVTIIGTRFEESPQRAARMLEREETADKPW----------------L 177

Query: 176 NKGESIRVFPLSNWTEQDIWQYIWLENIDIVP--LYLAAERPVLERDGMLMMIDDNRIDL 233
                  + P++ WT +++W+Y+     D  P  L  +    V  R           +  
Sbjct: 178 GDDNQWYLSPIAYWTMEEVWEYLGQCR-DGNPDVLTFSRFEEVF-RIYADAAGSSCAVVG 235

Query: 234 QPGEVIKKRMVRFRTLGCWPLT 255
                 + +    RT GC   T
Sbjct: 236 DMATKGQAKPCGART-GCAVCT 256


>UniRef50_Q22017 FAD synthetase region n=3 Tax=Caenorhabditis RepID=FLAD1_CAEEL
          Length = 519

 Score = 80.6 bits (197), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 43/227 (18%), Positives = 79/227 (34%), Gaps = 47/227 (20%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLAR-KAFYPGTLPF 58
            + ++  +++L  E+  I+ E+  ++      + ++ GKD +V+LHL R K         
Sbjct: 300 SENQIEFIQKL-NEAESIVEEIVEKYPLEQIALSFNGGKDCTVLLHLLRLKVDEKYGPST 358

Query: 59  PL--LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
           P+   H+    +F E  +F    AK Y  ++L    P  +  G+            + KT
Sbjct: 359 PIQGFHIMVEDQFPEATQFIIDAAKFYNIQVLEFPGP--LKTGLA----------ALKKT 406

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
                            G       SRA +    +      W                 +
Sbjct: 407 RP--------SIIPVLMG-------SRATDPNGKYMKTPVEW--------------TDSD 437

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
             + +RV P+ NWT  D+W  +    +    LY      +  RD  +
Sbjct: 438 WPQVLRVCPILNWTYTDVWHMLRGLCVPYCKLYDQGYTSLGGRDNTV 484


>UniRef50_C7TXS2 RFad1, flavin adenine dinucleotide synthetase, homolog n=1
           Tax=Schistosoma japonicum RepID=C7TXS2_SCHJA
          Length = 509

 Score = 80.6 bits (197), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 44/232 (18%), Positives = 80/232 (34%), Gaps = 57/232 (24%)

Query: 14  AESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAF-----------YPGTLPFPL 60
           AES+ II E   ++S    V+ ++ GKD +V+LHL                 P  LP  L
Sbjct: 259 AESVQIIEEALDKYSHSELVICFNGGKDCTVLLHLVHAVVQHLNNSNQESRKPTKLP-KL 317

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGS---AKHTDIMKTE 117
           L++ +   F E+  F ++T      ++    + E +   +  +          + +   E
Sbjct: 318 LYIRSHSTFPEIEIFVEKT-----VDVYYSSSNEILRPDLEKYEQKQTSVNSQSSLCSKE 372

Query: 118 G------------LKQAL-NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQR 164
                        L+  L +      AF G R  +  +R                     
Sbjct: 373 SGVVIYEGSIKSILENFLHDNPEIKGAFMGTRYTDPGAR--------------------- 411

Query: 165 PELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
            ++ H         + +R+ PL  WT  D+W ++   +I    LY      +
Sbjct: 412 -KMSHMMMSDPGWPQILRINPLLEWTYSDVWDFLRSLSIPYCSLYDVGYTSI 462


>UniRef50_Q16R18 Molybdopterin-binding n=3 Tax=Culicidae RepID=Q16R18_AEDAE
          Length = 217

 Score = 80.2 bits (196), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 34/227 (14%), Positives = 68/227 (29%), Gaps = 46/227 (20%)

Query: 8   HLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYP--GTLPFPLLHV 63
            L+    ++I +++   A +      + ++ GKD +V+L +  K             +++
Sbjct: 6   DLQIKLEKTIQLLKLAYATYKPEEIFLSFNGGKDCTVLLDIIMKMLPTIVSCNDLQCVYM 65

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
                F E+ EF D   K YG ++   +    +   +                       
Sbjct: 66  QPKEPFEEVEEFIDHCRKHYGIKIRAIRG--SIKSILEKICS------------------ 105

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
                 A   G+RR                             L           + +R+
Sbjct: 106 ENREIKACLMGSRR----------------------TDPYCGNLKLMQETDPGWPKMMRI 143

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
            PL +W   DIW+YI    +    LY      + ++   +   +  R
Sbjct: 144 SPLLDWNCSDIWEYILQNEVPYCSLYDRGYTSIGDKTNTIPNPNLKR 190


>UniRef50_UPI0000DB7DE3 PREDICTED: similar to CG4407-PA, isoform A n=1 Tax=Apis mellifera
           RepID=UPI0000DB7DE3
          Length = 390

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 48/272 (17%), Positives = 88/272 (32%), Gaps = 82/272 (30%)

Query: 18  HIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLP-FPLLHVDTGWKFREMYE 74
             ++ +  ++      + ++ GKD +V+LHLA        +     L+V     F E+  
Sbjct: 194 QFLKMLKMKYKPEEIFISFNGGKDCTVVLHLAACITKLQNISSLLCLYV-IAEPFPEVDS 252

Query: 75  FRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGG 134
           F ++  + Y  EL+  K+P  +A+              ++          +    A+  G
Sbjct: 253 FVEKAVQYYDLELIKKKSPMRLAL------------CSLL--------NERTNIKASLMG 292

Query: 135 ARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDI 194
            R+                     DP ++  E +   +   N    IRV P+ NW+   I
Sbjct: 293 MRK--------------------GDPGSENLEAFTPTDS--NWPNLIRVNPILNWSYDQI 330

Query: 195 WQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPL 254
           W+++   N+   PLY                                    + +LG    
Sbjct: 331 WKFLLKHNVPYCPLYDKG---------------------------------YTSLGTKST 357

Query: 255 TGA---VESNAQTLPEIIEEMLVSTTSERQGR 283
           T     +     T        L   ++ERQGR
Sbjct: 358 TIPNPRLRDPNDTSLYFPAYTLTDESTERQGR 389


>UniRef50_A1ZIJ8 Phosphoadenosine phosphosulfate reductase n=2 Tax=Microscilla
           marina ATCC 23134 RepID=A1ZIJ8_9SPHI
          Length = 476

 Score = 79.0 bits (193), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 50/282 (17%), Positives = 90/282 (31%), Gaps = 52/282 (18%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNP--VMLYSIGKDSSVMLHLARKAFYPGTL--- 56
           D  ++    Q+E     I+ +   E +N   ++ +S GKDS+++L L  K          
Sbjct: 5   DPTKMNIKEQVEQIKKEILEQYREEDNNRPWIIGFSGGKDSTMLLQLVWKTIQDNVPQDL 64

Query: 57  ---PFPLLHVDTGWKFREMYEFRDRTAKAY-------GCELLVHKNPEGVAM-------- 98
              P  ++  +T  +  ++  F +RT +         G  + V +    +          
Sbjct: 65  RTRPIHVICNNTLVENPKILSFVERTLEKIREASLAQGMPMTVEQTTPKLESSFWVNLIG 124

Query: 99  -GINPFVHGSAKHTDIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRD 153
            G           T+ +K     Q +      YG      G R DE   RAK        
Sbjct: 125 KGYPAPNTIFRWCTERLKINPTTQYIKDKISNYGEVIILLGTRSDESSQRAK-------- 176

Query: 154 RFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAE 213
              R + K QR       N            P+ +   +D+W Y+      + P +    
Sbjct: 177 NIKRHEIKGQRLRTHSLANA-------YAFTPIKDVLTKDVWTYLQA----VNPPWEGDN 225

Query: 214 RPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLT 255
           + ++     +     +   +           RF   GCW  T
Sbjct: 226 KELITL--YMSSSGGDCPIITDISTPSCGNSRF---GCWVCT 262


>UniRef50_A7RYI4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RYI4_NEMVE
          Length = 475

 Score = 77.5 bits (189), Expect = 5e-13,   Method: Composition-based stats.
 Identities = 37/203 (18%), Positives = 66/203 (32%), Gaps = 47/203 (23%)

Query: 19  IIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP---LLHVDTGWKFREMY 73
           +I+E    F      + ++ GKD +V+L++   A        P    L+V     F+E  
Sbjct: 279 VIQESLKLFRLDELCISFNGGKDCTVLLYIMYAAVAQSMAEVPKINALYVRHDSPFKEAE 338

Query: 74  EFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFG 133
            F + T + Y   L+        A+      H + K                    A   
Sbjct: 339 NFVEETTRLYNLNLICMSGKIKPALEELKKSHPNIK--------------------AILM 378

Query: 134 GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQD 193
           G RR +  +  K   +S+ D+                        E +R+ P+ +W  QD
Sbjct: 379 GTRRHDPFT-EKLHTFSWTDQ---------------------GWPEYLRINPILDWNHQD 416

Query: 194 IWQYIWLENIDIVPLYLAAERPV 216
           +W  +    +    LY      +
Sbjct: 417 VWSILLHCKVPYCTLYDNGYTSL 439


>UniRef50_B9IAG2 Predicted protein (Fragment) n=1 Tax=Populus trichocarpa
           RepID=B9IAG2_POPTR
          Length = 365

 Score = 77.1 bits (188), Expect = 7e-13,   Method: Composition-based stats.
 Identities = 35/211 (16%), Positives = 66/211 (31%), Gaps = 47/211 (22%)

Query: 9   LRQLEAES-IHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            ++LE  S + II +   +F     + +S  +D  V L L    F           +DTG
Sbjct: 29  AKELEKASPLAIINKALQDFIDGSAISFSGAED--VSLILQSGVFG----------LDTG 76

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
               +  +  D   K YG ++                         +++   L++AL   
Sbjct: 77  RLNSQTDKLLDDVEKYYGMDIEYMHQE----------------CCQVLQVRPLRRALKD- 119

Query: 127 GFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
              A   G R+D+    RA   +                                ++  P
Sbjct: 120 -LCAWITGQRKDQSPGIRATVPVLQIDHPSVEGIG--------------CGTISLVKWNP 164

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
           ++N   Q IW ++   N+ +  L+      +
Sbjct: 165 VANLGVQAIWNFLRTMNVPVNSLHALGYVSI 195


>UniRef50_UPI0001C369AF putative aminotransferase, class V n=1 Tax=Clostridium hathewayi
           DSM 13479 RepID=UPI0001C369AF
          Length = 345

 Score = 76.7 bits (187), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 48/245 (19%), Positives = 84/245 (34%), Gaps = 80/245 (32%)

Query: 20  IREVAAEFSNPVML-YSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDR 78
           IRE    +   V L YS G DS V+LHL R+         P +  +TG +F E+ +F  +
Sbjct: 34  IREWYDNWGGMVYLSYSGGLDSRVLLHLIRETV---GNDVPAVFSNTGLEFPEIVKFARQ 90

Query: 79  TAKA----------------------YGCELL-------VHKNPEGVAMG---------- 99
            +                        YG  L+       V+K   G              
Sbjct: 91  ASGEFREIYPVDKDGKRITFRKVITTYGYPLISKETARKVYKLRHGNLSDRHRNYLLNGD 150

Query: 100 ---------------INPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRA 144
                          IN     + K  ++MK +   + + + G      G  +DE   RA
Sbjct: 151 ERGSFGKLADKWQFLINAPFETTDKCCEMMKKKPFDKFVRETGRYPYI-GITQDEGFKRA 209

Query: 145 KERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENID 204
            +                     + +    +  G++I+  P+  WT+QD+ +Y+   +++
Sbjct: 210 HQ---------------------YAHTGCNVYDGKTIKSQPMGFWTKQDVLRYVVENDLE 248

Query: 205 IVPLY 209
           I  +Y
Sbjct: 249 ICSVY 253


>UniRef50_C7IJX2 Phosphoadenosine phosphosulfate reductase n=1 Tax=Clostridium
           papyrosolvens DSM 2782 RepID=C7IJX2_9CLOT
          Length = 276

 Score = 76.0 bits (185), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 54/257 (21%), Positives = 87/257 (33%), Gaps = 77/257 (29%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           ++ ++   L     ++  +I+E    +  N  + YS GKDS+V+ HL R+   P  L   
Sbjct: 41  LELLKSLPLDLKIIKTKILIQEAFDIYGSNIYVSYSGGKDSTVLSHLVRQ-LQPNILH-- 97

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE----------------------GVA 97
            +  +T  ++ E  +  +   +  G  +L+ K  +                       VA
Sbjct: 98  -IFSNTTCEYPETLQHINWEKEHNGMNILIVKPYDKYKKPWNFKRVVKEDGFPMYSKDVA 156

Query: 98  MGINPFVHG----------------------------SAKHTDIMKTEGLKQALNKYGFD 129
             I  +                               S K  + +K   +KQA  K G  
Sbjct: 157 NAIRTYRRAKSDKTRQNSIDYITRRFKRFLSYKDLNISDKCCEKLKKTPIKQAARKLGMQ 216

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN-GQINKGESIRVFPLSN 188
            A  G   +E                       QR   W NY     N  +  +  PLS 
Sbjct: 217 CAILGILAEES---------------------RQRELDWMNYGCNVFNVKKDNQCKPLSF 255

Query: 189 WTEQDIWQYIWLENIDI 205
           WTE DI++YI L N+ I
Sbjct: 256 WTENDIYEYIELYNLKI 272


>UniRef50_C7IDU2 Phosphoadenosine phosphosulfate reductase n=1 Tax=Clostridium
           papyrosolvens DSM 2782 RepID=C7IDU2_9CLOT
          Length = 313

 Score = 76.0 bits (185), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 50/248 (20%), Positives = 92/248 (37%), Gaps = 25/248 (10%)

Query: 12  LEAESIHIIR--EVAAEFSNP---VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           +E++SI +I+  E  A   +P    +  S GKDS   L L  KA     + F +    TG
Sbjct: 17  VESKSIELIKYFEPLALQHDPRGYCVAMSWGKDSMANLKLFIKA----GVKFFIQWNITG 72

Query: 67  WKFREMYEFRDRTAKAY---GCELLVHKNPEGVAMGI----NPFVHGSAKHTDIMKTEGL 119
               E+  F  R A      G +++     + +   I     P         D +K +  
Sbjct: 73  IDPPELIYFGRRQAYELELKGYKVIPIHPEKSMIQMIVDHCTPPTALMRYCCDELKEK-- 130

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           +  +NK    +   G R DE  SR+  R        ++ + +       +    ++   +
Sbjct: 131 RPEINKNCIHSF--GVRWDESPSRSNGREAMEVISKNKENIRLFNDNGENRKQFEVCMAK 188

Query: 180 SIRV-FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
            ++   P+ +WT + IW Y   E I    LY        +R G +     N+ + +    
Sbjct: 189 GVKALNPIISWTTEQIWDYHKAERITYCKLYDCG----FDRLGCVGCPLANKPNREFEFK 244

Query: 239 IKKRMVRF 246
           +     ++
Sbjct: 245 MFPEFKKY 252


>UniRef50_UPI00005251CA PREDICTED: similar to FAD1 flavin adenine dinucleotide synthetase
           homolog n=1 Tax=Ciona intestinalis RepID=UPI00005251CA
          Length = 516

 Score = 75.6 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 37/214 (17%), Positives = 66/214 (30%), Gaps = 49/214 (22%)

Query: 14  AESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHL-----ARKAFYPGTLPFPLLHVDTG 66
             S+ ++ E   ++      + ++ GKD + +LHL      R         F  L++   
Sbjct: 309 KSSLEVLEETLRKYEPHEICVGFNGGKDCTALLHLYHAALCRAGIEINPTNFKALYIKDK 368

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           + F E+ +F + +   Y   L                               +KQAL   
Sbjct: 369 YPFEEVEQFMESSVIRYKFHLTTMTGD-------------------------MKQALEAL 403

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
             D            S  K  +   R             +L        +    +RV PL
Sbjct: 404 KRD----------HPSI-KAVVMGTRCSD------PHSMDLSSFTMTDSDWPRFMRVNPL 446

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
            +WT  D+W+++    +    LY      +  RD
Sbjct: 447 LHWTYHDVWKFMRKLYLPYCVLYDKGYTSLGSRD 480


>UniRef50_Q8NFF5 FAD synthetase region n=38 Tax=Chordata RepID=FAD1_HUMAN
          Length = 587

 Score = 75.6 bits (184), Expect = 2e-12,   Method: Composition-based stats.
 Identities = 39/216 (18%), Positives = 69/216 (31%), Gaps = 48/216 (22%)

Query: 14  AESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP----LLHVDTGW 67
           A ++  I    A++S     + ++ GKD + +LHL   A        P    +L++ +  
Sbjct: 381 AGALQTIETSLAQYSLTQLCVGFNGGKDCTALLHLFHAAVQRKLPDVPNPLQILYIRSIS 440

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
            F E+ +F   T K Y  ++L  +     A+G     H                      
Sbjct: 441 PFPELEQFLQDTIKRYNLQMLEAEGSMKQALGELQARHP--------------------Q 480

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
            +A   G RR                             L             +R+ PL 
Sbjct: 481 LEAVLMGTRR----------------------TDPYSCSLCPFSPTDPGWPAFMRINPLL 518

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
           +WT +DIW ++    +    LY      +  R+  +
Sbjct: 519 DWTYRDIWDFLRQLFVPYCILYDRGYTSLGSRENTV 554


>UniRef50_Q8TYP8 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS
           reductase)/FAD synthetase fused to uncharacterized
           archaeal protein n=1 Tax=Methanopyrus kandleri
           RepID=Q8TYP8_METKA
          Length = 420

 Score = 75.2 bits (183), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 37/206 (17%), Positives = 69/206 (33%), Gaps = 25/206 (12%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L  L  +++  +  VA EF    +  S GKDS+  L +A +      +    ++VDTG+ 
Sbjct: 216 LENLFEDAVDFLGGVAEEFDVLFVPVSGGKDSTCCLAIAVETTDRLGIDVEAVYVDTGYD 275

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGI-NPFVHGSAKHTDIMKTEGLKQALNKYG 127
                +  +    A G ++      +    G+         +    +K  G+K+ L    
Sbjct: 276 LGR--DVVEDVGAALGVDIKHVDVSDAFERGLRERKPTHENRWCTGVKLSGIKKVLKDLE 333

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
            D       RD E  R + R    R+R                        +   V P+ 
Sbjct: 334 GDVLLVVGDRDAESRRRRLRPPVHRNRL----------------------LDVPEVNPVK 371

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAE 213
            W   ++   ++   + +  LY    
Sbjct: 372 GWGGAEVLGTLFRLGLPVSELYEIGF 397


>UniRef50_P77216 Uncharacterized protein ybdN n=243 Tax=Bacteria RepID=YBDN_ECOLI
          Length = 406

 Score = 75.2 bits (183), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 41/248 (16%), Positives = 69/248 (27%), Gaps = 42/248 (16%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L  LEA +   I           + +S GKDS +MLHL  +          +L +D   +
Sbjct: 10  LNILEA-ARERITWTLNTLPRVCVSFSGGKDSGLMLHLTAELARQMGKKICVLFIDWEAQ 68

Query: 69  FREMYEFRDRTAKAY----------GCELLVHKN------------PEGVAMGINP--FV 104
           F     +     + Y             L    +            P+   +   P   +
Sbjct: 69  FSCTINYVQSLRELYTDVIEEFYWVALPLTTQNSLSQYQPEWQCWEPDVEWVRQPPQDAI 128

Query: 105 HGSAKHTDIMKTEGLKQALNKY-------GFDAAFGGARRDEEKSRAKERIYSFRDRFHR 157
                          +Q + ++          A   G R DE  +R              
Sbjct: 129 TDPDFFCFYQPGMTFEQFVREFAEWFSQKRPAAMMIGIRADESYNR----------FVAI 178

Query: 158 WDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVL 217
                QR      +      G S  ++P+ +W   DIW +         PLY    +  +
Sbjct: 179 ASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTWYANHQSLCNPLYNLMYQAGV 238

Query: 218 ERDGMLMM 225
               M + 
Sbjct: 239 PLRHMRIC 246


>UniRef50_A8NQH7 Probable molybdopterin binding domain containing protein n=1
           Tax=Brugia malayi RepID=A8NQH7_BRUMA
          Length = 533

 Score = 74.8 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 40/196 (20%), Positives = 64/196 (32%), Gaps = 44/196 (22%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLP---FPLLHVDTGWKFREMYEFRDRTAKAYG 84
               + ++ GKD +++LHL R A      P      +H+  G  F EM +F   T K Y 
Sbjct: 342 DEIAIAFNGGKDCTLVLHLLRVAIDKKYGPGQTILGVHIVCGDSFPEMNQFIIDTTKRYN 401

Query: 85  CELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRA 144
             +L    P    +     +    K                      F G        RA
Sbjct: 402 IIVLEASGPVKEGLVQLKNMRPKLKC--------------------IFMGC-------RA 434

Query: 145 KERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENID 204
            +   S      ++   N     W  Y         +RV P+ +W+  D+W+ +    + 
Sbjct: 435 TDPSVSSMKSKCQFTDDN-----WPRY---------LRVCPILDWSYDDVWRALRGICMP 480

Query: 205 IVPLYLAAERPVLERD 220
             PLY      +  RD
Sbjct: 481 YCPLYDLGYTSLGGRD 496


>UniRef50_C4L4E5 Sulfurtransferase DndC n=3 Tax=Bacillales RepID=C4L4E5_EXISA
          Length = 551

 Score = 74.8 bits (182), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 49/281 (17%), Positives = 86/281 (30%), Gaps = 46/281 (16%)

Query: 10  RQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAF---YPGTLPFPLLHV-- 63
             +   SI +I+ V    + P V+ +S GKDS++   L  +A     P  L   +  +  
Sbjct: 16  DTVSRRSIDLIKRVYLNDTRPWVVGFSGGKDSTLTTQLIFEALLELSPEQLHKKVFIISS 75

Query: 64  DTGWKFREMYEFRD-------RTAKAYGCELLVHKNPEG---------VAMGINPFVHGS 107
           DT  +   +    +         A  Y   +   K             +  G        
Sbjct: 76  DTLVENPLVVSMINGSLHRMQEAAFKYNLPIETQKVKPLTEKTFWTNIIGRGYPTPNQTF 135

Query: 108 AKHTDIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQ 163
              TD +K +   + +     KYG      G R  E  SR +    S +D         +
Sbjct: 136 RWCTDRLKIDPANRFIKDKVSKYGEIIMVLGVRSSESTSRGQ----SIKDHEISGSELMR 191

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
              L + Y             P+  +   D+W Y+          +   ++  ++     
Sbjct: 192 HTSLANAY----------VFAPIKEFVLDDVWSYLLQNPAPWGEDHHKLQKMYMDSSSEC 241

Query: 224 MMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQT 264
            ++ D  I    G     R       GCW  T   +  + T
Sbjct: 242 PLVVDQNIKESAGSCGNSRF------GCWTCTVVNQDKSLT 276


>UniRef50_UPI0001BC4F2A hypothetical protein FuD12_09796 n=1 Tax=Fusobacterium sp. D12
           RepID=UPI0001BC4F2A
          Length = 424

 Score = 74.4 bits (181), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 46/260 (17%), Positives = 83/260 (31%), Gaps = 35/260 (13%)

Query: 15  ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
            +I  + ++ +E       +S GKDSSVML LA          F +L +D    ++   E
Sbjct: 13  ATIERLEKIFSENFAVYFSFSGGKDSSVMLQLANLVAKKKNKKFDVLFIDLEGNYKYTIE 72

Query: 75  FRDRTAKAYGCE--------LLVHKNPEGVAMGINPFV-HGSAKHTDIMKTEGLKQ--AL 123
                      +        L++  +   ++     +           M  + + +   L
Sbjct: 73  HVKELRNLSQIDEFYWVCLPLVLRNSVSQLSTHWLCWDKRQKEFWIRDMPKDCINEENYL 132

Query: 124 NKYGFDAAFGG----------ARRDEEKS----------RAKERIYSFRDRFHRWDPKNQ 163
           +KYG+D    G          A+  ++K           R  E    FR        K +
Sbjct: 133 SKYGWDFFISGMQFETFIVSFAKWYQKKHDKPVMCGVAIRTNESFNRFRAIVSLRKEKWK 192

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAER---PVLERD 220
               W               +P+ +W  +DIW  +   ++    LY    +    + E  
Sbjct: 193 DCN-WTTRVQTPWNLPIYNFYPIYDWETRDIWIAVSKFDLKYNKLYELLYKSGLSIHEAR 251

Query: 221 GMLMMIDDNRIDLQPGEVIK 240
                 DD R  L   + I+
Sbjct: 252 ICQPYGDDQRKGLNQFKAIE 271


>UniRef50_C4PZB7 Molybdopterin-binding, putative n=1 Tax=Schistosoma mansoni
           RepID=C4PZB7_SCHMA
          Length = 289

 Score = 74.4 bits (181), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 40/218 (18%), Positives = 71/218 (32%), Gaps = 58/218 (26%)

Query: 14  AESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYP------------GTLPFP 59
           A+S+  I E   ++S+   V+ ++ GKD + +LHL   A                     
Sbjct: 68  AKSLQCIEEALNKYSDSELVICFNGGKDCTALLHLIHAAIQHQSHNNNNHSENIKPRLPK 127

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           LL++ +   F E   F ++T   Y                ++    GS K         L
Sbjct: 128 LLYIRSCSSFPETELFVEKTVDVY--------------YSLSIVYEGSIK-------SAL 166

Query: 120 KQALNKY-GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           ++ L  Y     AF G R                             ++ +         
Sbjct: 167 ERFLGDYPEIRGAFMGTR----------------------YTDPGAYKMSYMVMSDPGWP 204

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
           + +R+ PL  WT  D+W ++   ++    LY A    +
Sbjct: 205 QILRINPLLEWTYSDVWNFLRSFSLPYCSLYDAGYTSI 242


>UniRef50_UPI0000D574FF PREDICTED: similar to RFad1, flavin adenine dinucleotide
           synthetase, homolog (yeast) n=1 Tax=Tribolium castaneum
           RepID=UPI0000D574FF
          Length = 455

 Score = 74.4 bits (181), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 45/210 (21%), Positives = 72/210 (34%), Gaps = 50/210 (23%)

Query: 14  AESIHIIREVAAEF--SNPVMLYSIGKD----SSVMLHLARKAFYPGTLPFPLLHVDTGW 67
             +I  I E   ++   N  + ++ GKD      ++L + +K F   + P P L+V +  
Sbjct: 246 KHAIENIEECLQQYGLENIFVSFNGGKDCTVLLHLVLTVVKKKFPQHSQPIPCLYVQSES 305

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY- 126
            F E  EF D     Y  +++V                           + L Q L KY 
Sbjct: 306 PFPEQDEFIDLCKCYYNLKIMVINAGI---------------------KDALGQILEKYP 344

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
            F A F G RR +  S     ++   D                      N  + +RV P+
Sbjct: 345 NFKACFMGTRRTDPYS-GDLTVFQMTDS---------------------NWPQILRVSPV 382

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
            +W   DIW Y+    +    LY      +
Sbjct: 383 LDWHYSDIWDYLLFYKVPYCKLYDLGFTSL 412


>UniRef50_B7FZY6 Predicted protein (Fragment) n=2 Tax=Bacillariophyta
           RepID=B7FZY6_PHATR
          Length = 403

 Score = 74.0 bits (180), Expect = 6e-12,   Method: Composition-based stats.
 Identities = 33/248 (13%), Positives = 71/248 (28%), Gaps = 50/248 (20%)

Query: 15  ESIHIIREVAAEFSNPVMLYSI--GKDSSVMLHLARKAFYP-------------GTLPFP 59
           ++++ +      +    ++ S   GKD+ V+LHL R A                  L   
Sbjct: 4   QALNNLDHAYRLYGPESVICSFNGGKDAVVILHLVRAAHARFYDQQRNLDGNPIEPLRPR 63

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           +++ +   +F E+  F       Y  +++  +     + G+   V  +            
Sbjct: 64  VVYFEHKDEFPEIRSFLREMVDVYELDMIAFEQGIKFSEGLKTLVTHNVPQN-------- 115

Query: 120 KQALNKYGFDAAFG-GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
               +   F  AF  G R  +  +R +                                 
Sbjct: 116 ----SNVSFPVAFVLGTRATDPNARGQGTF----------------------APSSHYMP 149

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +RV P+  WT   +W ++ L ++    LY      +      +               
Sbjct: 150 PFMRVNPVLEWTYGHVWHFLRLFHLPYCGLYDQGYTSLGTTKDTIPCPALTVPGGNTTNA 209

Query: 239 IKKRMVRF 246
           I +    +
Sbjct: 210 IPRYWPAY 217


>UniRef50_UPI0001C364B3 hypothetical protein ChatD1_04731 n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C364B3
          Length = 310

 Score = 73.7 bits (179), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 37/205 (18%), Positives = 59/205 (28%), Gaps = 39/205 (19%)

Query: 18  HIIRE--VAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEF 75
            +I+E  V A      + +S GKDS V+  L    F    +P+      T     E+  F
Sbjct: 16  QVIKELRVIAGCHTMCLRFSGGKDSVVLKWL----FDQAGIPYQARFSRTSVDPPELLRF 71

Query: 76  RDRTAKAYGCELLVHKNPEG----VAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAA 131
                + Y  +++           +     P            K    +    K G    
Sbjct: 72  I----RKYHSDVIEEPPRISMFHLIIKKGFPPTRVCRYCCSEYKE---RNTCPKEGHVLT 124

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
             G R+ E   R                    R E    Y G           P+ +WT+
Sbjct: 125 LTGVRKAESVKRRN----------------RSRVETCQAYKGVTF------FHPILDWTD 162

Query: 192 QDIWQYIWLENIDIVPLYLAAERPV 216
           + +W  I   +I    LY      +
Sbjct: 163 EQLWNVIDDNHIPYCELYDEGFSRI 187


>UniRef50_A8UF11 Phosphoadenosine phosphosulfate reductase n=1 Tax=Flavobacteriales
           bacterium ALC-1 RepID=A8UF11_9FLAO
          Length = 206

 Score = 73.7 bits (179), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 38/209 (18%), Positives = 70/209 (33%), Gaps = 34/209 (16%)

Query: 18  HIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRD 77
            I         N ++  S G  SSV+L               ++  DT +     Y    
Sbjct: 20  EIAEWALKLSDNYIVTTSFGIYSSVLL----STMSKLDKDIRVVWCDTLYNQPSTYNHAS 75

Query: 78  RTAKAYGCELLVHKN---PEGVAMGINPFVHGSAKH---TDIMKTEGLKQALNKYGFDAA 131
              K Y   +L +++    E +   I         H   ++ +K E  ++AL +   D  
Sbjct: 76  GLIKKYNLNILKYQSLYTKEEIDATIGLPSLEDDNHAIFSEAVKLEPFRRALTEQNPDVW 135

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
           F   R  + + R K+ I S+                        +K   ++V P   W++
Sbjct: 136 FTNIRVRQTEYRDKKDILSY------------------------SKDGILKVSPFYYWSD 171

Query: 192 QDIWQYIWLENIDIVPLYLAAERPVLERD 220
            D+  YI   ++     Y    + +L R+
Sbjct: 172 SDLDTYIEENHLAKNAYYFDPIKALLNRE 200


>UniRef50_D0MWH8 FAD synthetase, putative n=1 Tax=Phytophthora infestans T30-4
           RepID=D0MWH8_PHYIN
          Length = 291

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 40/259 (15%), Positives = 73/259 (28%), Gaps = 94/259 (36%)

Query: 9   LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTL---------- 56
           +++   +++ ++R     F        ++ GKDS+V+LHL R       L          
Sbjct: 25  MQKRLQKALDVMRSAIDIFGLEGVCFSFNGGKDSTVVLHLLRIVVAKRVLEEAQLAHLKA 84

Query: 57  ---------------------------------------PFPLLHVDTGWKFREMYEFRD 77
                                                    P+++ D+  +F E+ EF +
Sbjct: 85  EQEAENGPKTTVTSPRNSFVSADLLQEEELEARVKTQLQRVPVMYFDSYDQFPEVREFTE 144

Query: 78  RTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARR 137
                +     V+K                         EG+K  L+K      + G R 
Sbjct: 145 ECNTKFALSCHVYK-------------------CSF--VEGVKDILDKLQVKGIYMGVR- 182

Query: 138 DEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQY 197
                                DP  +  E  H           +RV P+  WT  D+W +
Sbjct: 183 -------------------GGDPYTEDME--HFSPSSPGWPPFLRVNPILKWTYDDVWSF 221

Query: 198 IWLENIDIVPLYLAAERPV 216
           +    ++   LY      +
Sbjct: 222 LRDCQLEYCSLYDHGYTSL 240


>UniRef50_Q6IWS1 Gp61 n=1 Tax=Burkholderia phage BcepB1A RepID=Q6IWS1_9CAUD
          Length = 248

 Score = 72.9 bits (177), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 45/206 (21%), Positives = 69/206 (33%), Gaps = 25/206 (12%)

Query: 29  NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELL 88
             V+  S GKDS   L LA  A          L  DT ++  + Y   +   K YG ++ 
Sbjct: 4   RIVIPISGGKDSQACLQLACAA--HARHEILGLFCDTNFEHPKTYAHVEFMRKFYGVKIQ 61

Query: 89  VHKNP---EGVAMGINPFVHGSAKHTDIMKTEGLKQALNK------YGFDAAFGGARRDE 139
                   E V         G+   TD +K    ++   +      +GF+  + G R  E
Sbjct: 62  SITAGSVLEKVWKYRRFPGGGARHCTDELKIVPSRKFYKELAENQGHGFEVWY-GMRLGE 120

Query: 140 EKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIW 199
              RAK      R R    +      E+   Y   +         PL  W   D+ +++ 
Sbjct: 121 STERAK------RYRDRIDNELYLPHEVLRKYPKYLGDMGIRFKLPLLEWDNVDVLEFLD 174

Query: 200 LENIDIVPLYLAAERPVLERDGMLMM 225
            +     PLY    R   +R G    
Sbjct: 175 GKE---NPLY----RDGFDRVGCFPC 193


>UniRef50_C0RZY2 FAD synthetase n=3 Tax=Paracoccidioides brasiliensis
           RepID=C0RZY2_PARBP
          Length = 347

 Score = 72.5 bits (176), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 48/265 (18%), Positives = 85/265 (32%), Gaps = 62/265 (23%)

Query: 6   LTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYP---------- 53
           L  ++     S+ +I+E    FS  +  + Y+ GKD  VML L   + +P          
Sbjct: 106 LHRVQNRTCTSLRVIQEALHRFSLQDLSLSYNGGKDCLVMLILFLASLHPFPAATKTATS 165

Query: 54  ----------GTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPF 103
                          P ++      FR + +F   ++ AY   L+ +           P 
Sbjct: 166 DNRKKSSTSSPPSTIPAIYAQPHHPFRSVEDFVASSSHAYHLSLVCYTTNP-------PH 218

Query: 104 VHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARR-DEEKSRAKERIYSFRDRFHRWDPKN 162
               +  T  +      +A+        F G RR D       E++  F    H W    
Sbjct: 219 ATIRSAFTSYLSLHPQIRAI--------FVGTRRTDPHG----EKLTHFDRTDHGW---- 262

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
                           + +R+ P+ +W   +IW +I    I+  PLY      +   +  
Sbjct: 263 ---------------PDFMRIHPVIDWHYAEIWAFIRHLGIEYCPLYDEGYTSLGGMNDT 307

Query: 223 LMMIDDNRIDLQPGEVIKKRMVRFR 247
                    D    +  + R  R+R
Sbjct: 308 HPNPKLQIRDQDSDDD-QHRKARYR 331


>UniRef50_UPI0000E49112 PREDICTED: similar to MGC82686 protein n=1 Tax=Strongylocentrotus
           purpuratus RepID=UPI0000E49112
          Length = 479

 Score = 72.5 bits (176), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 35/208 (16%), Positives = 69/208 (33%), Gaps = 53/208 (25%)

Query: 14  AESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP----LLHVDTGW 67
           A ++ +I E   ++        ++ GKD + ++HL           +     +L++    
Sbjct: 316 AVAVKVIEEALEKYKMDEICAGFNGGKDCTALIHLFHAVVKRKYPDYKGQLQVLYIQHPH 375

Query: 68  -KFREMYEFRDRTAKAYGCE--LLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
             F+E+ EF D + K Y  +  L+  +  + +                + K+        
Sbjct: 376 GTFKEVDEFVDESVKRYNLKTILIQGRIKDALWE--------------LKKSNP------ 415

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
                A   G R+ +    A    +S  D            E W          E +RV 
Sbjct: 416 --SIKAVLMGTRQTD-PHSASLSNFSPTD------------EGW---------PELMRVN 451

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAA 212
           P+  W+  D+W ++    +    LY   
Sbjct: 452 PMLFWSYHDVWVFLRRLFVPYCRLYDKG 479


>UniRef50_C4G023 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G023_ABIDE
          Length = 537

 Score = 72.5 bits (176), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 55/305 (18%), Positives = 96/305 (31%), Gaps = 54/305 (17%)

Query: 31  VMLYSIGKDSSVMLHLARKAFY--PGTLPFPLLHV---DTGWKFREMYEFRDRTAKAYGC 85
           V+ YS GKDS+  L L   A    P      ++HV   DT  +   + ++ +++ K    
Sbjct: 31  VIGYSGGKDSTATLQLVWYALRELPAEKLTKVVHVINTDTLVESPVIEKWVEKSLKMMDE 90

Query: 86  E-----------LLVHKNPEGVAM--------GINPFVHGSAKHT-DIMKTEGLKQALN- 124
                        + H+    V             PF     +   D +K + + + +  
Sbjct: 91  SSSKIPSKVNTLFVTHRLTPAVDNTYWVNFIGRGYPFPRKKLRWCTDRLKIQPVNKFVKD 150

Query: 125 ---KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
              ++G      G R+ E  +RA+   Y             ++  +    +        +
Sbjct: 151 KIAEHGEIILVLGTRKAESAARARTMTY------------YEKKRVRELLSPNPTLANEL 198

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
              PL +WT  D+W ++                  L+   M    D     +        
Sbjct: 199 VFSPLEDWTNNDVWVFLMQYENP-----WGLSNHELQTLYMSATEDKECPMMTEKNQPTC 253

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTS---ERQGRVIDRDQAGSMELKKR 298
              RF   GCW  T  VE +      I  E   +  +   E + R  D D+       K+
Sbjct: 254 GQSRF---GCWVCT-MVEKDKSMEAMISNEDEKAWMTPLLEFRNRFGDEDKDRGRRSFKK 309

Query: 299 Q-GYF 302
             GY 
Sbjct: 310 MQGYL 314


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_A1U3Y0 Sulfate adenylyltransferase subunit 2 1 n=49 Tax...   322   1e-86
UniRef50_B8H5U7 Sulfate adenylyltransferase subunit 2 n=3 Tax=Al...   313   5e-84
UniRef50_B8IRX8 Sulfate adenylyltransferase subunit 2 n=167 Tax=...   312   1e-83
UniRef50_Q07UU1 Sulfate adenylyltransferase subunit 2 n=177 Tax=...   304   2e-81
UniRef50_B9JT86 Sulfate adenylyltransferase subunit 2 n=6 Tax=Ba...   301   2e-80
UniRef50_B3PTD3 Sulfate adenylyltransferase subunit 2 n=214 Tax=...   294   3e-78
UniRef50_Q1WLL1 Sulfate adenylate transferase subunit 2 n=3 Tax=...   291   2e-77
UniRef50_C9KJS8 Sulfate adenylyltransferase, subunit 2 n=1 Tax=M...   287   4e-76
UniRef50_B5E9A6 Phosphoadenosine phosphosulfate reductase n=3 Ta...   258   1e-67
UniRef50_A1TDE9 Sulfate adenylyltransferase subunit 2 n=357 Tax=...   255   1e-66
UniRef50_D1J9F7 Sulfate adenylyltransferase subunit 2 n=1 Tax=un...   248   2e-64
UniRef50_Q07QS4 Sulfate adenylyltransferase subunit 2 n=35 Tax=B...   238   2e-61
UniRef50_Q24TA1 Sulfate adenylyltransferase subunit 2 n=12 Tax=B...   230   4e-59
UniRef50_Q13BZ7 Sulfate adenylyltransferase subunit 2 n=7 Tax=Br...   228   1e-58
UniRef50_B3SFD5 Putative uncharacterized protein (Fragment) n=2 ...   223   8e-57
UniRef50_B4D6P6 Sulfate adenylyltransferase n=1 Tax=Chthoniobact...   195   1e-48
UniRef50_C0QUE3 Phosphoadenosine phosphosulfate reductase n=1 Ta...   183   5e-45
UniRef50_Q310R0 Phosphoadenylylsulfate reductase (Thioredoxin) n...   183   5e-45
UniRef50_C6BYK7 Phosphoadenosine phosphosulfate reductase n=2 Ta...   183   1e-44
UniRef50_Q0W1C8 Putative 3\'-phosphoadenosine 5\'-phosphosulfate...   178   2e-43
UniRef50_C3MM97 Phosphoadenosine phosphosulfate reductase n=1 Ta...   175   2e-42
UniRef50_Q72BR8 Phosphoadenosine phosphosulfate reductase, putat...   173   7e-42
UniRef50_B1I6V6 Phosphoadenosine phosphosulfate reductase n=1 Ta...   171   3e-41
UniRef50_C6D4K6 Adenylylsulfate reductase, thioredoxin dependent...   171   4e-41
UniRef50_C8WSE6 Adenylylsulfate reductase, thioredoxin dependent...   170   6e-41
UniRef50_A9S2B6 Predicted protein n=3 Tax=Embryophyta RepID=A9S2...   170   6e-41
UniRef50_A7TD47 Predicted protein n=1 Tax=Nematostella vectensis...   168   3e-40
UniRef50_D2R2B5 Phosphoadenosine phosphosulfate reductase n=5 Ta...   167   4e-40
UniRef50_Q12WD1 Phosphoadenosine phosphosulfate reductase n=1 Ta...   166   6e-40
UniRef50_D1YYA8 Putative phosphoadenosine phosphosulfate reducta...   165   1e-39
UniRef50_A1RXY7 Phosphoadenosine phosphosulfate reductase n=1 Ta...   165   1e-39
UniRef50_Q2FND9 Phosphoadenosine phosphosulfate reductase n=7 Ta...   165   2e-39
UniRef50_Q1ITG5 Phosphoadenylylsulfate reductase (Thioredoxin) n...   164   4e-39
UniRef50_D1CDF4 Phosphoadenosine phosphosulfate reductase n=2 Ta...   164   4e-39
UniRef50_C5A452 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   163   5e-39
UniRef50_C5U5U5 Phosphoadenosine phosphosulfate reductase n=1 Ta...   162   1e-38
UniRef50_D1YW88 Putative phosphoadenosine phosphosulfate reducta...   162   2e-38
UniRef50_Q60377 Uncharacterized protein MJ0066 n=5 Tax=Methanoca...   162   2e-38
UniRef50_Q0W3A3 Putative 3\'-phosphoadenosine 5\'-phosphosulfate...   162   2e-38
UniRef50_A2SQI0 Phosphoadenosine phosphosulfate reductase n=3 Ta...   161   2e-38
UniRef50_Q55309 Phosphoadenosine phosphosulfate reductase n=3 Ta...   161   3e-38
UniRef50_Q12UR6 Phosphoadenosine phosphosulfate reductase fused ...   160   4e-38
UniRef50_Q58383 Uncharacterized protein MJ0973 n=11 Tax=Methanoc...   160   6e-38
UniRef50_D1I5Z9 Whole genome shotgun sequence of line PN40024, s...   160   6e-38
UniRef50_A9AB03 Phosphoadenosine phosphosulfate reductase n=7 Ta...   160   7e-38
UniRef50_C7NUQ7 Phosphoadenosine phosphosulfate reductase n=12 T...   160   7e-38
UniRef50_D0LSJ1 Phosphoadenosine phosphosulfate reductase n=1 Ta...   159   9e-38
UniRef50_A4WMI9 Phosphoadenosine phosphosulfate reductase n=5 Ta...   158   2e-37
UniRef50_Q5HKZ5 Phosphoadenosine phosphosulfate reductase n=110 ...   158   3e-37
UniRef50_B5IFS1 Phosphoadenosine phosphosulfate reductase n=2 Ta...   157   4e-37
UniRef50_Q2S5G4 Phosphoadenosine phosphosulfate reductase n=2 Ta...   156   6e-37
UniRef50_B0T3S8 Phosphoadenosine phosphosulfate reductase n=7 Ta...   156   6e-37
UniRef50_Q1GFS4 Phosphoadenylylsulfate reductase (Thioredoxin) n...   156   8e-37
UniRef50_D2EEN4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   155   1e-36
UniRef50_C5QND2 Phosphoadenosine phosphosulfate reductase n=5 Ta...   155   2e-36
UniRef50_C6P7J4 Adenylylsulfate reductase, thioredoxin dependent...   154   2e-36
UniRef50_A7NG75 Phosphoadenosine phosphosulfate reductase n=2 Ta...   154   3e-36
UniRef50_B0C9W9 Phosphoadenosine phosphosulfate reductase n=1 Ta...   154   5e-36
UniRef50_Q467V4 Phosphoadenosine phosphosulfate reductase n=3 Ta...   153   5e-36
UniRef50_A2BN02 Phosphoadenosine phosphosulfate reductase n=1 Ta...   153   7e-36
UniRef50_B8GLW1 Phosphoadenosine phosphosulfate reductase n=1 Ta...   153   8e-36
UniRef50_Q9YA63 Putative uncharacterized protein n=1 Tax=Aeropyr...   153   8e-36
UniRef50_B8ELQ2 Phosphoadenosine phosphosulfate reductase n=8 Ta...   153   9e-36
UniRef50_P56860 Phosphoadenosine phosphosulfate reductase n=4 Ta...   152   1e-35
UniRef50_P72794 Phosphoadenosine phosphosulfate reductase n=23 T...   152   1e-35
UniRef50_A2BKK3 Phosphoadenosine 5'-phosphosulfate reductase n=1...   152   2e-35
UniRef50_Q164V6 Phosophoadenylyl-sulfate reductase n=24 Tax=Rhod...   151   2e-35
UniRef50_Q01NE3 Adenylylsulfate kinase / phosphoadenylylsulfate ...   151   2e-35
UniRef50_Q2Y9X1 Phosphoadenylylsulfate reductase (Thioredoxin) n...   151   3e-35
UniRef50_A6Q5M8 Phosphoadenosine phosphosulfate reductase n=1 Ta...   151   4e-35
UniRef50_A1SC70 Phosphoadenylylsulfate reductase (Thioredoxin) n...   151   4e-35
UniRef50_C9RRS4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   151   4e-35
UniRef50_B9XLS6 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   150   4e-35
UniRef50_P92979 5'-adenylylsulfate reductase 1, chloroplastic n=...   149   9e-35
UniRef50_D0N1L8 Phosphoadenosine phosphosulfate reductase n=2 Ta...   149   9e-35
UniRef50_A4XB35 Phosphoadenylylsulfate reductase (Thioredoxin) n...   149   1e-34
UniRef50_B6ASY4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   149   1e-34
UniRef50_Q3YAU0 5'-adenylylsulfate reductase n=2 Tax=Viridiplant...   149   1e-34
UniRef50_A7MSZ6 Phosphoadenosine phosphosulfate reductase n=283 ...   148   3e-34
UniRef50_Q1AXE9 Phosphoadenylylsulfate reductase (Thioredoxin) n...   147   4e-34
UniRef50_B7R5I5 Iron-sulfur protein n=1 Tax=Thermococcus sp. AM4...   147   5e-34
UniRef50_Q11B66 Phosphoadenosine phosphosulfate reductase n=36 T...   147   6e-34
UniRef50_C5SCG2 Adenylylsulfate reductase, thioredoxin dependent...   146   9e-34
UniRef50_B5Y5U1 Predicted protein (Fragment) n=1 Tax=Phaeodactyl...   146   9e-34
UniRef50_Q7NK24 Phosphoadenosine phosphosulfate reductase n=6 Ta...   146   1e-33
UniRef50_Q3ICV8 Putative enzyme protein n=4 Tax=Gammaproteobacte...   145   2e-33
UniRef50_Q2FU39 Uncharacterized domain 2 n=2 Tax=Methanomicrobia...   145   2e-33
UniRef50_A7HWV2 Phosphoadenosine phosphosulfate reductase n=1 Ta...   145   2e-33
UniRef50_Q8DK35 Phosphoadenosine phosphosulfate reductase n=9 Ta...   145   2e-33
UniRef50_C0GLN5 Phosphoadenosine phosphosulfate reductase n=1 Ta...   144   3e-33
UniRef50_C9KJN4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   144   3e-33
UniRef50_A5W608 Phosphoadenylylsulfate reductase (Thioredoxin) n...   144   3e-33
UniRef50_B8GIL3 Aminotransferase class V n=2 Tax=Archaea RepID=B...   144   3e-33
UniRef50_Q1UZN4 Putative uncharacterized protein n=1 Tax=Candida...   144   5e-33
UniRef50_B3T667 Putative phosphoadenosine phosphosulfate reducta...   143   6e-33
UniRef50_C4L4E5 Sulfurtransferase DndC n=3 Tax=Bacillales RepID=...   143   7e-33
UniRef50_B1VHQ3 Adenosine phosphosulfate reductase n=17 Tax=Cory...   143   1e-32
UniRef50_Q8RG73 Phosphoadenosine phosphosulfate reductase n=3 Ta...   142   1e-32
UniRef50_B0D4U7 Predicted protein n=2 Tax=Agaricales RepID=B0D4U...   142   1e-32
UniRef50_A8AAE7 Phosphoadenosine phosphosulfate reductase n=1 Ta...   142   1e-32
UniRef50_A4YFD1 Phosphoadenylylsulfate reductase (Thioredoxin) n...   142   1e-32
UniRef50_B5IDE7 Phosphoadenosine phosphosulfate reductase family...   142   1e-32
UniRef50_D2RH85 Phosphoadenosine phosphosulfate reductase n=1 Ta...   142   2e-32
UniRef50_D2L597 Phosphoadenosine phosphosulfate reductase n=1 Ta...   141   2e-32
UniRef50_C2TXL3 Sulfurtransferase DndC n=1 Tax=Bacillus cereus R...   141   2e-32
UniRef50_C1AUL1 Phosphoadenosine phosphosulfate reductase n=11 T...   141   3e-32
UniRef50_C4LKR1 Adenosine phosphosulfate reductase n=5 Tax=Actin...   141   3e-32
UniRef50_A3DN95 Phosphoadenosine phosphosulfate reductase n=2 Ta...   141   4e-32
UniRef50_A2EL13 Putative uncharacterized protein n=2 Tax=Trichom...   141   4e-32
UniRef50_B4WAM0 Phosophoadenylyl-sulfate reductase subfamily, pu...   140   4e-32
UniRef50_C4XSH1 Putative adenylyltransferase n=1 Tax=Desulfovibr...   140   5e-32
UniRef50_C0CT99 Putative uncharacterized protein n=1 Tax=Clostri...   140   5e-32
UniRef50_Q2G577 Phosphoadenylylsulfate reductase (Thioredoxin) n...   140   5e-32
UniRef50_C1A1H0 Phosphoadenosine phosphosulfate reductase n=21 T...   140   7e-32
UniRef50_A8AC84 Phosphoadenosine phosphosulfate reductase n=1 Ta...   140   7e-32
UniRef50_Q2JFN1 Phosphoadenylylsulfate reductase (Thioredoxin) n...   140   7e-32
UniRef50_B8CCL3 Phosphoadenosine-phosphosulphate reductase n=1 T...   139   8e-32
UniRef50_P56859 Phosphoadenosine phosphosulfate reductase n=12 T...   139   8e-32
UniRef50_A1ZIJ8 Phosphoadenosine phosphosulfate reductase n=2 Ta...   139   9e-32
UniRef50_Q2W561 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   139   1e-31
UniRef50_Q3B2L6 Phosphoadenylylsulfate reductase (Thioredoxin) n...   139   1e-31
UniRef50_C6WVG4 Adenylylsulfate reductase, thioredoxin dependent...   139   1e-31
UniRef50_A3DLJ9 Phosphoadenosine phosphosulfate reductase n=1 Ta...   139   1e-31
UniRef50_C1SHC5 PAPS reductase/FAD synthetase family protein n=1...   138   2e-31
UniRef50_A1VQ08 Phosphoadenylylsulfate reductase (Thioredoxin) n...   138   3e-31
UniRef50_A2C6A4 Phosphoadenosine phosphosulfate reductase n=27 T...   137   5e-31
UniRef50_A9A540 Adenylylsulfate reductase, thioredoxin dependent...   136   8e-31
UniRef50_B2GI28 Adenosine 5'-phosphosulfate reductase n=24 Tax=A...   136   1e-30
UniRef50_C5ETD1 Phosphoadenosine phosphosulfate reductase n=4 Ta...   136   1e-30
UniRef50_Q30U94 Phosphoadenylylsulfate reductase (Thioredoxin) n...   136   1e-30
UniRef50_A6WVB8 Phosphoadenosine phosphosulfate reductase n=2 Ta...   136   1e-30
UniRef50_Q5KLW1 Phosphoadenylyl-sulfate reductase (Thioredoxin),...   135   2e-30
UniRef50_Q3A3P4 Phosphoadenylylsulfate reductase (Thioredoxin) n...   135   2e-30
UniRef50_B1L7P4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   135   2e-30
UniRef50_C5TAI7 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   135   2e-30
UniRef50_Q8IR76 CG4407, isoform B n=8 Tax=Drosophila RepID=Q8IR7...   134   3e-30
UniRef50_Q4JBE9 Conserved Archaeal protein n=1 Tax=Sulfolobus ac...   134   3e-30
UniRef50_UPI000186D96A molybdopterin- binding protein, putative ...   134   4e-30
UniRef50_Q9VYI5 CG4407, isoform A n=4 Tax=melanogaster subgroup ...   134   4e-30
UniRef50_C1XVG3 Phosphoadenylylsulfate reductase (Thioredoxin) n...   134   4e-30
UniRef50_A1SNA9 Phosphoadenylylsulfate reductase (Thioredoxin) n...   134   5e-30
UniRef50_Q0BUS4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   133   6e-30
UniRef50_C2HVQ6 Putative uncharacterized protein n=1 Tax=Vibrio ...   133   6e-30
UniRef50_C6Y361 Phosphoadenosine phosphosulfate reductase n=2 Ta...   133   7e-30
UniRef50_C4G023 Putative uncharacterized protein n=1 Tax=Abiotro...   133   7e-30
UniRef50_A6GTB0 Phosphoadenosine phosphosulfate reductase n=3 Ta...   133   1e-29
UniRef50_Q8UH67 Phosphoadenosine phosphosulfate reductase n=10 T...   132   1e-29
UniRef50_A5PAV0 Phosphoadenosine phosphosulfate reductase n=1 Ta...   132   2e-29
UniRef50_P18408 Phosphoadenosine phosphosulfate reductase n=50 T...   131   2e-29
UniRef50_A1WQX9 Phosphoadenylylsulfate reductase (Thioredoxin) n...   131   3e-29
UniRef50_C7G6A6 Phosphoadenosine phosphosulfate reductase n=3 Ta...   131   3e-29
UniRef50_A3UHA4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   131   4e-29
UniRef50_B3RLV6 Putative uncharacterized protein (Fragment) n=1 ...   131   4e-29
UniRef50_UPI000169461E phosphoadenosine phosphosulfate reductase...   130   6e-29
UniRef50_A5INH9 Phosphoadenosine phosphosulfate reductase n=2 Ta...   130   6e-29
UniRef50_A5E7W2 Phosphoadenosine phosphosulfate reductase n=3 Ta...   130   7e-29
UniRef50_Q11AI4 Phosphoadenosine phosphosulfate reductase n=5 Ta...   130   7e-29
UniRef50_UPI0001C3554A hypothetical protein ChatD1_24037 n=1 Tax...   129   8e-29
UniRef50_Q7M9C9 APS REDUCTASE n=1 Tax=Wolinella succinogenes Rep...   129   9e-29
UniRef50_A9KBQ9 Phosphoadenosine phosphosulfate reductase n=3 Ta...   129   9e-29
UniRef50_B5Y6E1 Phosphoadenosine phosphosulfate reductase family...   129   9e-29
UniRef50_A6L476 Putative sulfate adenylate transferase, subunit ...   129   1e-28
UniRef50_A9DP87 Putative uncharacterized protein n=1 Tax=Kordia ...   129   1e-28
UniRef50_Q8TXP0 Predicted RNA modification enzyme consisting of ...   129   1e-28
UniRef50_C6QHX4 Adenylylsulfate reductase, thioredoxin dependent...   129   1e-28
UniRef50_B1I2U8 Phosphoadenosine phosphosulfate reductase n=1 Ta...   129   1e-28
UniRef50_Q2S6R6 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   129   1e-28
UniRef50_UPI000038E1FC phosphoadenosine phosphosulfate reductase...   128   2e-28
UniRef50_Q758M0 AEL259Wp n=1 Tax=Eremothecium gossypii RepID=Q75...   128   2e-28
UniRef50_Q9JRT1 Phosphoadenosine phosphosulfate reductase n=103 ...   128   2e-28
UniRef50_B1YPZ9 Sulfurtransferase DndC n=2 Tax=Proteobacteria Re...   128   3e-28
UniRef50_A8IWB7 FAD synthetase n=1 Tax=Chlamydomonas reinhardtii...   128   3e-28
UniRef50_Q39RP8 Phosphoadenylylsulfate reductase (Thioredoxin) n...   128   3e-28
UniRef50_B8D5B9 Phosphoadenosine phosphosulfate reductase n=1 Ta...   128   3e-28
UniRef50_A2BJV9 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   128   3e-28
UniRef50_Q3MB09 Phosphoadenosine phosphosulfate reductase n=24 T...   127   4e-28
UniRef50_Q0ASV0 Phosphoadenylylsulfate reductase (Thioredoxin) n...   127   4e-28
UniRef50_B6YXY8 3'-phosphoadenosine 5'-phosphosulfate reductase ...   127   4e-28
UniRef50_B2V3F8 Putative sulfurtransferase DndC n=2 Tax=Clostrid...   127   5e-28
UniRef50_Q3SNX7 Phosphoadenylylsulfate reductase (Thioredoxin) n...   126   8e-28
UniRef50_Q0EZE5 Phosphoadenosine phosphosulfate reductase n=1 Ta...   126   8e-28
UniRef50_A1KL82 Phosphoadenosine phosphosulfate reductase n=31 T...   126   1e-27
UniRef50_Q8NFF5 FAD synthetase region n=38 Tax=Chordata RepID=FA...   126   1e-27
UniRef50_C6E124 Phosphoadenosine phosphosulfate reductase n=1 Ta...   125   2e-27
UniRef50_Q1Q0N4 Similar to phosphoadenosine phosphosulfate reduc...   125   2e-27
UniRef50_A3TKH9 Phosphoadenosine phosphosulfate reductase n=3 Ta...   125   2e-27
UniRef50_D0TBT8 Phosphoadenosine phosphosulfate reductase n=3 Ta...   125   2e-27
UniRef50_C4WUE8 ACYPI004304 protein n=2 Tax=Acyrthosiphon pisum ...   124   3e-27
UniRef50_D1IAI6 Whole genome shotgun sequence of line PN40024, s...   124   3e-27
UniRef50_A3DMN4 Phosphoadenosine phosphosulfate reductase n=1 Ta...   124   3e-27
UniRef50_Q16R18 Molybdopterin-binding n=3 Tax=Culicidae RepID=Q1...   124   4e-27
UniRef50_C7JH54 Phosphoadenosine phosphosulfate reductase n=8 Ta...   123   8e-27
UniRef50_Q8MZ99 AT21573p n=9 Tax=Drosophila RepID=Q8MZ99_DROME        123   8e-27
UniRef50_A6CAR6 Phosphoadenosine phosphosulfate reductase n=2 Ta...   123   9e-27
UniRef50_D2BJ99 Phosphoadenosine phosphosulfate reductase n=2 Ta...   122   1e-26
UniRef50_UPI00016C68DD hypothetical protein CdifQCD-6_15821 n=1 ...   122   1e-26
UniRef50_A7RYI4 Predicted protein n=1 Tax=Nematostella vectensis...   122   1e-26
UniRef50_C1F5K5 Putative sulfurtransferase DndC n=1 Tax=Acidobac...   122   1e-26
UniRef50_C3XHV9 Phosphoadenosine phosphosulfate reductase n=1 Ta...   122   1e-26
UniRef50_Q8GA37 Z1203 protein n=70 Tax=Bacteria RepID=Q8GA37_ECOLX    122   1e-26
UniRef50_B8FTN0 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   122   2e-26
UniRef50_Q2RT16 Phosphoadenylylsulfate reductase (Thioredoxin) n...   122   2e-26
UniRef50_D1HPZ6 Whole genome shotgun sequence of line PN40024, s...   121   2e-26
UniRef50_Q0RWS5 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   121   3e-26
UniRef50_Q11WI2 Phosphoadenylylsulfate reductase (Thioredoxin) n...   121   3e-26
UniRef50_A3UEI0 Phosphoadenosine phosphosulfate reductase n=1 Ta...   121   3e-26
UniRef50_UPI0001C36A5F hypothetical protein ChatD1_04226 n=1 Tax...   121   4e-26
UniRef50_B7UDE0 Adenosine phosphosulfate reductase n=1 Tax=Coryn...   120   5e-26
UniRef50_O74841 Probable FAD synthetase n=2 Tax=Schizosaccharomy...   120   5e-26
UniRef50_UPI00005251CA PREDICTED: similar to FAD1 flavin adenine...   120   5e-26
UniRef50_UPI0000DB7DE3 PREDICTED: similar to CG4407-PA, isoform ...   120   5e-26
UniRef50_B1YE28 Phosphoadenosine phosphosulfate reductase n=1 Ta...   120   5e-26
UniRef50_A5G4D4 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   120   6e-26
UniRef50_A1UQ75 Phosphoadenosine phosphosulfate reductase n=3 Ta...   120   7e-26
UniRef50_C7IJX0 Phosphoadenosine phosphosulfate reductase n=1 Ta...   120   8e-26
UniRef50_B7FZY6 Predicted protein (Fragment) n=2 Tax=Bacillariop...   119   8e-26
UniRef50_Q1VVA9 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   119   9e-26
UniRef50_Q4P7E8 Putative uncharacterized protein n=1 Tax=Ustilag...   119   1e-25
UniRef50_D0JAV6 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   119   1e-25
UniRef50_A1WA11 3'-phosphoadenosine 5'-phosphosulfate sulfotrans...   119   1e-25
UniRef50_B8KW50 Phosphoadenosine phosphosulfate reductase n=1 Ta...   119   1e-25
UniRef50_C0RZY2 FAD synthetase n=3 Tax=Paracoccidioides brasilie...   119   1e-25
UniRef50_B9Q2H9 Cancer-associated gene protein, putative n=2 Tax...   119   2e-25
UniRef50_Q97JS3 Similar to phospho-adenylylsulfate sulfotransfer...   119   2e-25
UniRef50_B6QDU1 FAD synthetase, putative n=1 Tax=Penicillium mar...   119   2e-25
UniRef50_A3RYW5 Co-activator of prophage gene expression IbrA n=...   118   2e-25
UniRef50_C5K7J4 FAD synthetase, putative n=1 Tax=Perkinsus marin...   118   2e-25
UniRef50_C7TXS2 RFad1, flavin adenine dinucleotide synthetase, h...   118   2e-25
UniRef50_Q0VNW4 Phosphoadenosine phosphosulfate reductase n=5 Ta...   118   2e-25
UniRef50_Q22017 FAD synthetase region n=3 Tax=Caenorhabditis Rep...   118   3e-25
UniRef50_Q04PC4 Phosphoadenylyl-sulfate reductase n=10 Tax=Bacte...   117   4e-25
UniRef50_B4D6P5 Phosphoadenylyl-sulfate reductase (Thioredoxin) ...   117   4e-25
UniRef50_A6EMB0 Phosphoadenosine phosphosulfate reductase n=1 Ta...   117   4e-25
UniRef50_D1PAG4 ATP synthase F0, A subunit n=1 Tax=Prevotella co...   117   4e-25
UniRef50_A9USG3 Predicted protein (Fragment) n=1 Tax=Monosiga br...   117   5e-25
UniRef50_Q0RVM7 Probable phosphoadenylyl-sulfate reductase (Thio...   117   5e-25
UniRef50_A0Z1B4 Possible 3'-phosphoadenosine 5'-phosphosulfate s...   116   8e-25
UniRef50_Q74M42 NEQ525 n=1 Tax=Nanoarchaeum equitans RepID=Q74M4...   116   1e-24
UniRef50_P77216 Uncharacterized protein ybdN n=243 Tax=Bacteria ...   115   2e-24
UniRef50_A8A8R5 Phosphoadenosine phosphosulfate reductase n=1 Ta...   115   2e-24
UniRef50_A8H4Y9 Phosphoadenosine phosphosulfate reductase n=15 T...   115   2e-24
UniRef50_A2DE77 Phosphoadenosine phosphosulfate reductase family...   115   2e-24
UniRef50_B5YMF1 Predicted protein (Fragment) n=1 Tax=Thalassiosi...   115   2e-24
UniRef50_B9ZQQ7 Phosphoadenosine phosphosulfate reductase n=1 Ta...   114   3e-24
UniRef50_UPI0000D574FF PREDICTED: similar to RFad1, flavin adeni...   114   6e-24
UniRef50_A0DD33 Chromosome undetermined scaffold_46, whole genom...   113   7e-24
UniRef50_C5PEQ4 Phosphoadenosine phosphosulfate reductase domain...   113   7e-24
UniRef50_Q54RS3 Putative uncharacterized protein n=1 Tax=Dictyos...   113   9e-24
UniRef50_Q11FT5 Phosphoadenosine phosphosulfate reductase n=1 Ta...   112   1e-23
UniRef50_B7J801 Conserved domain protein n=1 Tax=Acidithiobacill...   112   1e-23

Sequences not found previously or not previously below threshold:

>UniRef50_A1U3Y0 Sulfate adenylyltransferase subunit 2 1 n=49 Tax=Bacteria
           RepID=CYSD1_MARAV
          Length = 304

 Score =  322 bits (824), Expect = 1e-86,   Method: Composition-based stats.
 Identities = 234/302 (77%), Positives = 264/302 (87%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +   + THL+QLEAESIHIIREVAAEF NPVMLYSIGKDS+VMLHLA KAF PG  PFPL
Sbjct: 3   LTPPKKTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLAMKAFAPGKPPFPL 62

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           +HVDT WKFREM  FRD+ A+  G +LLVH N EGV  GI PF HGSAKHTD+MKT+ LK
Sbjct: 63  MHVDTTWKFREMITFRDQMAEKLGMKLLVHTNQEGVEQGIGPFTHGSAKHTDVMKTQALK 122

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           QAL+KYGFDAAFGGARRDEEKSRAKER+YSFRD+FHRWDPKNQRPELW+ YNG++NKGES
Sbjct: 123 QALDKYGFDAAFGGARRDEEKSRAKERVYSFRDKFHRWDPKNQRPELWNLYNGKVNKGES 182

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
           IRVFPLSNWTE DIWQYI+LENIDIVPLY AAERPV+ERDG L+M+DD+R+ L+PGE   
Sbjct: 183 IRVFPLSNWTELDIWQYIYLENIDIVPLYYAAERPVVERDGTLIMVDDDRMPLEPGEQPM 242

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
            +MVRFRTLGC+PLTGAVES A TLP+II+EML++TTSERQGRVID D A SME KKR+G
Sbjct: 243 MKMVRFRTLGCYPLTGAVESEAATLPDIIQEMLLTTTSERQGRVIDHDGAASMEQKKREG 302

Query: 301 YF 302
           YF
Sbjct: 303 YF 304


>UniRef50_B8H5U7 Sulfate adenylyltransferase subunit 2 n=3 Tax=Alphaproteobacteria
           RepID=B8H5U7_CAUCN
          Length = 326

 Score =  313 bits (801), Expect = 5e-84,   Method: Composition-based stats.
 Identities = 221/302 (73%), Positives = 254/302 (84%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +   RLTHL++LEAESIHI+REVAAE   PVMLYSIGKDS+VMLHLA KAFYP   PFPL
Sbjct: 25  ITPARLTHLQRLEAESIHILREVAAECERPVMLYSIGKDSAVMLHLAAKAFYPSKPPFPL 84

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           LH+DT WKFR+MY  RDR     G +LLVHKNP+  A GINPF HGSA HTD+ KTEGLK
Sbjct: 85  LHIDTTWKFRDMYALRDRIGSEMGFDLLVHKNPDAQARGINPFDHGSAVHTDLWKTEGLK 144

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           QAL+KYGFDAAFGGARRDEEKSRAKER++SFR   HRWDPKNQRPELW+ YN + + GES
Sbjct: 145 QALSKYGFDAAFGGARRDEEKSRAKERVFSFRSSEHRWDPKNQRPELWNLYNTRKHPGES 204

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
           +RVFP+SNWTE DIWQYI LENI IVPLY AAERPV+ERDG L+M+DD+R  L+ GEV +
Sbjct: 205 LRVFPISNWTELDIWQYIHLENIPIVPLYFAAERPVVERDGALIMVDDDRFRLRDGEVPQ 264

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
            R VRFRTLGC+PLTGAVES A TLP++I+EML++TTSERQGRVID DQ+ SME KK++G
Sbjct: 265 MRSVRFRTLGCYPLTGAVESTAATLPQVIQEMLLATTSERQGRVIDHDQSASMEKKKQEG 324

Query: 301 YF 302
           YF
Sbjct: 325 YF 326


>UniRef50_B8IRX8 Sulfate adenylyltransferase subunit 2 n=167 Tax=Bacteria
           RepID=CYSD_METNO
          Length = 312

 Score =  312 bits (798), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 211/302 (69%), Positives = 241/302 (79%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +D  RLTHL++LEAESIHI+RE  AE  NPVMLYSIGKDSSV+LHLA KAF PG LPFPL
Sbjct: 11  LDTPRLTHLQRLEAESIHIMRETVAETENPVMLYSIGKDSSVLLHLALKAFAPGRLPFPL 70

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           LHVDT WKFREM  FRD  AK  G +LLV+ NP+G+A GI P  HGS  HTD+MKT+ L+
Sbjct: 71  LHVDTTWKFREMIAFRDARAKELGLDLLVYTNPDGLARGIGPVSHGSEVHTDVMKTQALR 130

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           QAL+KY FDAAFGGARRDEE SRAKERI S R   HRWDPK QR E WH YN +  +GES
Sbjct: 131 QALDKYKFDAAFGGARRDEEASRAKERIVSLRTAQHRWDPKRQRAEPWHLYNLKKKRGES 190

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
           +RVFPLSNWTE DIW YI  E I IVPLY +AERPV+ RDG L+M+DD R+ L+PGE  +
Sbjct: 191 LRVFPLSNWTELDIWLYIEQERIPIVPLYFSAERPVVRRDGQLIMVDDERLPLEPGETPE 250

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
            R VRFRTLGC+PLTGAVES+A TLPEII E L + TSERQGRVID+D AG+ME KK++G
Sbjct: 251 LRKVRFRTLGCYPLTGAVESDAATLPEIIGETLAARTSERQGRVIDKDGAGAMERKKQEG 310

Query: 301 YF 302
           YF
Sbjct: 311 YF 312


>UniRef50_Q07UU1 Sulfate adenylyltransferase subunit 2 n=177 Tax=Bacteria
           RepID=CYSD_RHOP5
          Length = 328

 Score =  304 bits (779), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 206/296 (69%), Positives = 241/296 (81%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
           +HL++LE+ESIHI+REVAAEF  PVMLYSIGKDSSV+LHLA KAF PG  PFPLLHVDT 
Sbjct: 33  SHLQRLESESIHILREVAAEFRKPVMLYSIGKDSSVLLHLAMKAFAPGKPPFPLLHVDTT 92

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           WKFREM  FRD+  +  G +LLVH NP+GVA  + PF HGSA+HTD+MKT+ L+QAL+ +
Sbjct: 93  WKFREMIAFRDQRIRELGLDLLVHVNPDGVAQRVGPFSHGSARHTDVMKTQALRQALDAH 152

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           GFDAA GGARRDEEKSRAKERI+S R   HRWDPKNQRPELW  YN  +  GES+RVFPL
Sbjct: 153 GFDAAIGGARRDEEKSRAKERIFSHRSAAHRWDPKNQRPELWSLYNTMLAPGESMRVFPL 212

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
           SNWTE DIW YI +E I IVPLY AAERPV+ERDG L+++DD R+ L+PGEV + R VRF
Sbjct: 213 SNWTELDIWDYILIERIPIVPLYFAAERPVVERDGALILVDDERMPLRPGEVPQWRSVRF 272

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           RTLGC+PLTGAV S A TLP I++EM+ S +SER+GRVIDRD   SME KK +GYF
Sbjct: 273 RTLGCYPLTGAVPSTATTLPAIVQEMMASRSSEREGRVIDRDSTASMERKKAEGYF 328


>UniRef50_B9JT86 Sulfate adenylyltransferase subunit 2 n=6 Tax=Bacteria
           RepID=CYSD_AGRVS
          Length = 316

 Score =  301 bits (770), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 199/295 (67%), Positives = 240/295 (81%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           HL+ LE E+IHI REVA EF NPVMLYSIGKDSSV+LHLARKAFYPG +PFPLLH+DTGW
Sbjct: 22  HLKALENEAIHIFREVAGEFDNPVMLYSIGKDSSVLLHLARKAFYPGRVPFPLLHIDTGW 81

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
           KF+EM  FRD  AK Y  +L+VH NP G   G+ PF HGSA +TDIMKTE L+QAL+   
Sbjct: 82  KFKEMIAFRDEMAKRYDLDLVVHTNPRGKTEGVTPFSHGSALYTDIMKTEALRQALDAGK 141

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           +DAAFGGARRDEE SRAKERIYSFR   H+WDP+NQRPELW+ YNG I +GES+R FPLS
Sbjct: 142 YDAAFGGARRDEEASRAKERIYSFRTPDHKWDPRNQRPELWNVYNGMIRRGESVRAFPLS 201

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           NWTE DIW+YI  ENI +VPLY A +RP +ERDGM+++ +D R++L PGE ++   +RFR
Sbjct: 202 NWTEVDIWRYIQAENIPLVPLYFAEKRPFIERDGMMILAEDERLELLPGEKVQHGSIRFR 261

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           TLGC+PLTGA+ S A+TL ++I E+ ++T SERQGR IDRDQ+GSME KKR+GYF
Sbjct: 262 TLGCFPLTGALRSEARTLDDVIAELEIATVSERQGRAIDRDQSGSMEKKKREGYF 316


>UniRef50_B3PTD3 Sulfate adenylyltransferase subunit 2 n=214 Tax=Bacteria
           RepID=CYSD_RHIE6
          Length = 317

 Score =  294 bits (751), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 205/295 (69%), Positives = 237/295 (80%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           HL+ LE ESIHI REVAAEF  PVMLYSIGKDSSV+LHLARKAFYPG +PFPLLHV+TGW
Sbjct: 23  HLKALENESIHIFREVAAEFERPVMLYSIGKDSSVLLHLARKAFYPGRVPFPLLHVNTGW 82

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
           KFREM  FRD TAK Y  +L+ H NP G A  I PF HGSA  TDIMKTE L+QAL+   
Sbjct: 83  KFREMIAFRDETAKKYDLDLIEHINPRGAAENITPFTHGSAAFTDIMKTESLRQALDAGQ 142

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           FDAAFGGARRDEE SRAKERIYSFR   HRWDP+NQRPELW+ YNG I KGES+R FPLS
Sbjct: 143 FDAAFGGARRDEEASRAKERIYSFRTPDHRWDPRNQRPELWNVYNGMIRKGESVRAFPLS 202

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           NWTE DIW+YI  E+I +VPLY A  R  +ERDGM+++ +D R++L PGEV ++ M+RFR
Sbjct: 203 NWTEVDIWRYIQAEDIPLVPLYYAKMRKFVERDGMMILAEDPRLELLPGEVRQEGMIRFR 262

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           TLG +PLTGA+ S A TL E+I E+ ++T SERQGR IDRDQ+GSME KKR+GYF
Sbjct: 263 TLGDFPLTGAIRSQATTLQEVIAELEIATVSERQGRAIDRDQSGSMEKKKREGYF 317


>UniRef50_Q1WLL1 Sulfate adenylate transferase subunit 2 n=3 Tax=Proteobacteria
           RepID=Q1WLL1_RHIME
          Length = 297

 Score =  291 bits (745), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 196/293 (66%), Positives = 238/293 (81%), Gaps = 1/293 (0%)

Query: 10  RQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
           ++LEAESI I REVAA F+ PVM+YSIGKDSSV+LHLARKAFYP ++PFPLLH+DT WKF
Sbjct: 6   QRLEAESIEIFREVAASFARPVMMYSIGKDSSVLLHLARKAFYPSSIPFPLLHIDTTWKF 65

Query: 70  REMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
            +M  FR+R A+ YG EL VH N +GVA GINPF HGSA +TDIMKT+ L+QAL+  G+D
Sbjct: 66  SQMIGFRNRMAEEYGFELRVHTNADGVAQGINPFDHGSA-YTDIMKTQALRQALSSGGYD 124

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
           AA GGARRDEEKSRAK+RI+S R+  H WDPKNQRPELW  +N ++  GES+RV+PLSNW
Sbjct: 125 AAIGGARRDEEKSRAKDRIFSHRNAHHAWDPKNQRPELWRLFNTRLAPGESMRVYPLSNW 184

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
           TE DIW YI++E+I IVPLY A  RPV+ER G L+M+DD+R  L  GE   +++VRFRTL
Sbjct: 185 TELDIWTYIYVEDIPIVPLYFARPRPVVERSGTLIMVDDDRFRLDKGETPTEQVVRFRTL 244

Query: 250 GCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           GC+PLTGA+ SNA TL EII E+  S TSER+GR+ID DQAGSME KK++GYF
Sbjct: 245 GCYPLTGAIRSNAATLAEIIMEIQGSRTSEREGRLIDGDQAGSMEKKKQEGYF 297


>UniRef50_C9KJS8 Sulfate adenylyltransferase, subunit 2 n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KJS8_9FIRM
          Length = 302

 Score =  287 bits (733), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 201/301 (66%), Positives = 238/301 (79%), Gaps = 4/301 (1%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           +L+HL  LEAE+I+IIREVAAE   PVMLYSIGKDS+VM+HLA KAFYP   PFP LH++
Sbjct: 3   KLSHLDALEAEAIYIIREVAAESEKPVMLYSIGKDSTVMMHLALKAFYPEKPPFPFLHIN 62

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           T WKF EM  FRD  AK YG +++ +KN EG+A G+NPF +G A +TDIMKT+ LKQAL 
Sbjct: 63  TTWKFHEMIAFRDAQAKKYGLDMIEYKNEEGLAAGVNPFDYG-ASYTDIMKTQALKQALT 121

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           KYGF AAFGG RRDEEKSRAKER++SFR+    WDPKNQRPE+W  YN QINKGESIRVF
Sbjct: 122 KYGFTAAFGGGRRDEEKSRAKERVFSFRNAAQAWDPKNQRPEMWKLYNSQINKGESIRVF 181

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ---PGEVIKK 241
           PLSNWTE+DIWQYI  EN++IV LY A ERPV+ERDG L+MIDD+RI  +     E I+ 
Sbjct: 182 PLSNWTEKDIWQYIRRENLEIVSLYFAKERPVIERDGNLIMIDDDRIVKKLNLKPEDIEH 241

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGY 301
           + VRFRTLGC+PLTGAVES+A TL  I+EE L +  SER  RVID + AGSME +KR+GY
Sbjct: 242 KKVRFRTLGCYPLTGAVESDADTLDAIVEETLGAVESERTSRVIDHEGAGSMERRKREGY 301

Query: 302 F 302
           F
Sbjct: 302 F 302


>UniRef50_B5E9A6 Phosphoadenosine phosphosulfate reductase n=3 Tax=Proteobacteria
           RepID=B5E9A6_GEOBB
          Length = 268

 Score =  258 bits (659), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 119/298 (39%), Positives = 169/298 (56%), Gaps = 31/298 (10%)

Query: 6   LTHLRQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           + +L+ LE++S+++IRE   +F     ML+S+GKDS+ +L L RKAF+ G +PFP++H+D
Sbjct: 1   MHYLQALESKSVYVIREAYQKFNGRIAMLWSVGKDSTTLLWLVRKAFF-GKIPFPVMHID 59

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           TG+KF EMYEFRDR AK +G EL+V  N E +A G+ P           +KT  LKQA++
Sbjct: 60  TGYKFPEMYEFRDRLAKEWGFELIVASNKEQLAKGMGPSSGLKLDCCTELKTNALKQAVD 119

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           +YGF +   G RRDE   RAKER +S RD   +WD +NQ  E+W  YN  + + E  R+ 
Sbjct: 120 QYGFQSILLGIRRDEHGIRAKERYFSPRDAEFQWDYENQPAEVWDQYNSFLREDEHYRIH 179

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P+ ++TE DIW+YI  E I IV LY                                   
Sbjct: 180 PILHFTELDIWRYIQREQIPIVDLYR-----------------------------SNGGK 210

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           R+R++GC P    V S A T+ E+I E+  ST SER GR  D++   +M+  +  GY 
Sbjct: 211 RYRSIGCVPCCNPVPSEAATIEEMIAELETSTDSERAGRAQDKENLYTMQKLRSLGYM 268


>UniRef50_A1TDE9 Sulfate adenylyltransferase subunit 2 n=357 Tax=cellular organisms
           RepID=CYSD_MYCVP
          Length = 309

 Score =  255 bits (652), Expect = 1e-66,   Method: Composition-based stats.
 Identities = 160/298 (53%), Positives = 197/298 (66%), Gaps = 5/298 (1%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           L+HLR LEAE+IHIIREVAAEF  PV+L+S GKDS VMLHLA KAF PG LPFP++HVDT
Sbjct: 16  LSHLRALEAEAIHIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFRPGRLPFPVMHVDT 75

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNK 125
           G  F E+   RD      G  L+V K  + +  G       S    + M+T  L +A+ +
Sbjct: 76  GHNFEEVLAARDELVAESGVRLVVAKVQDDIDAGRVVETIPSR---NPMQTFTLLRAIRE 132

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
             FDAAFGGARRDEEK+RAKER++SFRD F +WDPKNQRPELW+ YNG+  KGE IR FP
Sbjct: 133 NKFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKNQRPELWNLYNGRHRKGEHIRAFP 192

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           LSNWTE DIW YI  E I +  +Y A +R V ERDGML+ +  +    +  E I ++ VR
Sbjct: 193 LSNWTEFDIWSYIGAEKIKLPSIYYAHQRKVFERDGMLLAVHKHLQP-RKDEPIIEKSVR 251

Query: 246 FRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQG-RVIDRDQAGSMELKKRQGYF 302
           FRT+G    TG VES A T+ E+I E  +S  +ER   R  DR     ME +KR+GYF
Sbjct: 252 FRTVGDVTCTGCVESTAATVSEVIAETAISRLTERGATRADDRISEAGMEDRKREGYF 309


>UniRef50_D1J9F7 Sulfate adenylyltransferase subunit 2 n=1 Tax=uncultured archaeon
           RepID=D1J9F7_9ARCH
          Length = 271

 Score =  248 bits (633), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 117/300 (39%), Positives = 172/300 (57%), Gaps = 37/300 (12%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L++LE +SI+I+RE  AEF NP +L+S+GKDS+  L L RKAF  G +PFP++H+DTG+K
Sbjct: 3   LKELENKSIYILREAYAEFENPAILWSMGKDSTTALWLCRKAFL-GEIPFPVIHIDTGYK 61

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
           F++MYEFRDR A+ +G +L++ KN E +  G+ P   G  +    +KTE L   L+K+ F
Sbjct: 62  FKQMYEFRDRIAEEWGFDLVITKNEEAINAGMGP-KDGKLECCTKLKTEALMNYLDKHRF 120

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN-----KGESIRV 183
           DA F   RRDE   RAKER++S RD   RW+ ++Q  E+W  Y  Q            RV
Sbjct: 121 DALFLAIRRDEHGIRAKERVFSPRDEEFRWNYRDQPLEMWDQYQTQGRSEKGAVQNHTRV 180

Query: 184 FPLSNWTEQDIWQYIWLE-NIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
            P+ +W E D+W+YI  E +I + P+Y A                               
Sbjct: 181 HPILHWRELDVWEYIKQEKDIPVNPMYFANN----------------------------- 211

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
             R+R+LGC P T  ++S A+T+ EI+EE+  +  +ER GR  D+++A  M+  +  GY 
Sbjct: 212 GKRYRSLGCEPCTSPIDSTAKTIDEIVEELRTTKVAERSGRAQDKEKAFMMQKLRALGYM 271


>UniRef50_Q07QS4 Sulfate adenylyltransferase subunit 2 n=35 Tax=Bacteria
           RepID=Q07QS4_RHOP5
          Length = 296

 Score =  238 bits (607), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 118/299 (39%), Positives = 164/299 (54%), Gaps = 37/299 (12%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           + HL QLEA+SI+I+RE  A      +L+S+GKDS+VM+ LARKAF+ G +PFP +HVDT
Sbjct: 33  MDHLDQLEAQSIYILREAFARLKKLALLWSLGKDSNVMIWLARKAFF-GRVPFPAMHVDT 91

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNP--EGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           G KF EMY FRD+ +K +  +L++   P  E V   + P    +A      KTEGLK AL
Sbjct: 92  GKKFPEMYAFRDQYSKEWDLDLILEYCPGIESVDPTLPPAARSAA-----RKTEGLKLAL 146

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
            K+GFD    G RRDEE +RAKER++S R     WD ++Q PE W  +N     G  +R+
Sbjct: 147 AKHGFDGLIAGIRRDEEATRAKERVFSPRGTEGGWDVRDQPPEFWDQFNASPPPGSHLRI 206

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            P+ +WTE DIW Y   ENI I+PLY                             + +  
Sbjct: 207 HPILHWTEADIWAYTKRENIPIIPLY-----------------------------LSQGG 237

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
            R+R+LG   +T  V S A  + EI++E+  +   ER GR +D +   + E  +  GY 
Sbjct: 238 QRYRSLGDADITNPVASTASNIDEILKELDETKVPERAGRALDHETEDAFERLRVAGYL 296


>UniRef50_Q24TA1 Sulfate adenylyltransferase subunit 2 n=12 Tax=Bacteria
           RepID=Q24TA1_DESHY
          Length = 293

 Score =  230 bits (587), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 112/322 (34%), Positives = 161/322 (50%), Gaps = 54/322 (16%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           + HL +LEA+S++I+RE   EF N  ML+SIGKDS+V+L LARKAF+ G +P PL+H+DT
Sbjct: 1   MNHLDKLEAQSVYILREAYREFKNICMLWSIGKDSTVLLWLARKAFF-GHVPIPLVHIDT 59

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFV--HGSAKHTDIMKTEGLKQAL 123
            +K  EM  +RD  A+ +   ++  +N E +  G                +KTE LK  L
Sbjct: 60  HYKIPEMIHYRDELARQWRLTMIYGENKEALDGGRTFPDGKTDRISCCQALKTEALKNTL 119

Query: 124 --------------------NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQ 163
                               N+  +     G R DEE SR+KER +S RD+ + WD  +Q
Sbjct: 120 SGEWSRYILDLETGQYRPDGNREKYTGVIVGVRADEEGSRSKERYFSPRDQENDWDVGDQ 179

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
            PE W+ +      G  IR+ PL +WTE ++W+YI  E I +  LY              
Sbjct: 180 PPEFWNQFKTDFAPGTHIRIHPLLDWTELNVWEYIQREKIPVTSLYFD------------ 227

Query: 224 MMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEM---LVSTTSER 280
                           +    R+R+LGC+P T  VES A+ + EIIEE+     +  +ER
Sbjct: 228 ----------------QGEGKRYRSLGCYPCTLPVESPARNVEEIIEELRSGKFANIAER 271

Query: 281 QGRVIDRDQAGSMELKKRQGYF 302
            GR  D+D  G +E  +R GY 
Sbjct: 272 SGRAQDKDDGGGLETLRRGGYM 293


>UniRef50_Q13BZ7 Sulfate adenylyltransferase subunit 2 n=7 Tax=Bradyrhizobiaceae
           RepID=Q13BZ7_RHOPS
          Length = 291

 Score =  228 bits (582), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 120/299 (40%), Positives = 162/299 (54%), Gaps = 37/299 (12%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
           + HL  LEA+SI+I RE  A      +L+S+GKDS+VM+ LARKAF+ G +PFP LHVDT
Sbjct: 28  MDHLDALEAQSIYIFREGFARLKKLALLWSLGKDSNVMIWLARKAFF-GRVPFPALHVDT 86

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNP--EGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           G KF EMY FRD+ +K +  +L V   P  + V   + P    +A      KTEGLK AL
Sbjct: 87  GKKFPEMYAFRDQYSKEWELDLRVDPCPPIDSVDPTLPPAARSAA-----RKTEGLKLAL 141

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
            KYGFD    G RRDEE +RAKER++S R     WD ++Q PE W  +N     G  +R+
Sbjct: 142 AKYGFDGLIAGIRRDEEATRAKERVFSPRGTEGGWDVRDQPPEFWDQFNASPPPGAHLRI 201

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            P+ +WTE DIW Y   ENI I+PLY                             + +  
Sbjct: 202 HPILHWTEADIWAYTKRENIPIIPLY-----------------------------LAQNG 232

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
            R+R+LG   +T  V SNA ++ EI+ E+  +   ER GR +D +   + E  +  GY 
Sbjct: 233 KRYRSLGDQDITFPVASNASSIDEILHELQTTKVPERAGRALDHETEDAFERLRVAGYL 291


>UniRef50_B3SFD5 Putative uncharacterized protein (Fragment) n=2 Tax=cellular
           organisms RepID=B3SFD5_TRIAD
          Length = 421

 Score =  223 bits (567), Expect = 8e-57,   Method: Composition-based stats.
 Identities = 163/212 (76%), Positives = 183/212 (86%)

Query: 4   IRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
             LTHLRQLEAESIHI REVAAEF NPVMLYS+GKDSSV+LHLARKAF PG +PFPL+HV
Sbjct: 210 PSLTHLRQLEAESIHIFREVAAEFENPVMLYSVGKDSSVLLHLARKAFAPGKIPFPLMHV 269

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           +T WKFREM EFRD+ A+ YG EL+ + NPEG    I PF HGSAK+TDIMKT+ LKQAL
Sbjct: 270 NTTWKFREMIEFRDKMAEKYGFELISYTNPEGADNKITPFTHGSAKYTDIMKTQALKQAL 329

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           +KY FDAAFGGARRDEEKSRAKER++SFRD+ HRWDPKNQRPELW+ YN QINKGESIRV
Sbjct: 330 DKYQFDAAFGGARRDEEKSRAKERVFSFRDKNHRWDPKNQRPELWNIYNAQINKGESIRV 389

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERP 215
           FP+SNWTE DIWQYI++ENI+I  LYLA  RP
Sbjct: 390 FPMSNWTELDIWQYIYMENIEIPSLYLAKPRP 421


>UniRef50_B4D6P6 Sulfate adenylyltransferase n=1 Tax=Chthoniobacter flavus Ellin428
           RepID=B4D6P6_9BACT
          Length = 283

 Score =  195 bits (496), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 114/244 (46%), Positives = 152/244 (62%), Gaps = 1/244 (0%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           M   +L HL+ LE ESIHI+REVAAEF  P +L+S GKDS  +L LA KAF P  +P P 
Sbjct: 1   MSSYQLDHLQYLETESIHIMREVAAEFERPTILFSGGKDSICLLRLAEKAFRPSDIPMPF 60

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           L+VDTG  F E+ EFRDR A   G +L+V K  + +A GI     G       ++   L 
Sbjct: 61  LNVDTGHHFPELNEFRDRRAAELGGKLIVRKVEDAIASGIAVPTPGEISRN-RLQIPTLL 119

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
            A++++ FD A GGARRDEEK+RAKER +SFRD F +WDP+NQRPE+W+ YN ++N GE+
Sbjct: 120 AAIDEFQFDCAIGGARRDEEKARAKERFFSFRDSFGQWDPRNQRPEIWNVYNARVNPGEN 179

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
           +RVFPLSNWTE DIW+YI  E +++  +Y + +RP       +   D  R         +
Sbjct: 180 MRVFPLSNWTEMDIWEYIKREKLEVPAIYFSHKRPGGAPRWSVAAGDGYRSAEGKRGSAR 239

Query: 241 KRMV 244
               
Sbjct: 240 DGGP 243


>UniRef50_C0QUE3 Phosphoadenosine phosphosulfate reductase n=1 Tax=Persephonella
           marina EX-H1 RepID=C0QUE3_PERMH
          Length = 235

 Score =  183 bits (465), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 52/294 (17%), Positives = 93/294 (31%), Gaps = 81/294 (27%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           + R  H   L   +  +++ V   F N     S   D   ++H+ ++          ++ 
Sbjct: 8   KERSDHFENL--PAQDLLKWVYQNFKNVGFTSSFSADDVSIIHMIKEI----KPDALIIF 61

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTE 117
           +DT + F E YE   +  + +   L + K       +    G   +     K   I K E
Sbjct: 62  IDTDYHFPETYELVKKIKEEWDINLKIIKPLITVEEQDRLYGEKLYEKDPDKCCQIRKVE 121

Query: 118 GLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
            LK+ L +   D    G RRD+  +RA                               + 
Sbjct: 122 PLKRVLEEL--DVWITGMRRDQSPTRANIGKVETHR--------------------LPSG 159

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
              ++V P+++WT +D+W+Y+   N+   PLY                            
Sbjct: 160 KTILKVNPIADWTRKDVWKYVHENNLPYNPLYDQ-------------------------- 193

Query: 238 VIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                   + ++GC P T  V               +    ER GR   + +  
Sbjct: 194 -------NYLSIGCAPCTRPV---------------LEGEDERAGRWAGKGKLE 225


>UniRef50_Q310R0 Phosphoadenylylsulfate reductase (Thioredoxin) n=2
           Tax=Desulfovibrio RepID=Q310R0_DESDG
          Length = 267

 Score =  183 bits (465), Expect = 5e-45,   Method: Composition-based stats.
 Identities = 63/303 (20%), Positives = 106/303 (34%), Gaps = 79/303 (26%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNP---VMLYSIGKDSSVMLHLARKAFYPGTL--PFP 59
           R+  L Q  A +  ++  + +  + P   V+ ++ GKDS+V+L L R       +  P  
Sbjct: 39  RMIQLSQKTAYARSLLETIISNGTPPSSVVVAWTGGKDSTVVLDLWRNVLRNAGISAPPR 98

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           +L +DTG KF E+  FRD+ A ++   + +   P        P           +K   L
Sbjct: 99  VLSLDTGCKFPEVTTFRDKLAASWQLNMHIVTPP--ADNTGYPVAANVVDCCRRLKVLPL 156

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           + A+          G RRDE  +RA                             ++    
Sbjct: 157 QHAVESLNVSILLTGIRRDEHPARASSGHAE-----------------------KVISPP 193

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
             R+ P+ ++ E D+W Y +   +   PLY                              
Sbjct: 194 HQRLHPIFDFNEMDVWAYTFERQLPYCPLYDEG--------------------------- 226

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQ 299
                 +R+LGC P T    + +                ERQGR   ++Q  +M+  +  
Sbjct: 227 ------YRSLGCKPCTSPPTNTS--------------GHERQGRNAVKEQ--NMQTLRSL 264

Query: 300 GYF 302
           GYF
Sbjct: 265 GYF 267


>UniRef50_C6BYK7 Phosphoadenosine phosphosulfate reductase n=2 Tax=Desulfovibrio
           RepID=C6BYK7_DESAD
          Length = 234

 Score =  183 bits (463), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 69/302 (22%), Positives = 106/302 (35%), Gaps = 85/302 (28%)

Query: 9   LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPF------PL 60
           L    A S  ++  +   +      + ++ GKDS+V+L L R+                 
Sbjct: 10  LDDKVAHSAGLMSGMLEMYPPERIAVAWTGGKDSTVVLALWREVLKNKGKEASLVLVPQA 69

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           L +DTG KF E+  FRDR A  +G ++ V +    V +   P      K    +K + L+
Sbjct: 70  LSIDTGIKFPEVMAFRDRIALQWGVDVKVIRPD--VDLSSYPIAENPVKCCADLKIKPLQ 127

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           +A++++  D    G RRDE  SRA  R    RD                         + 
Sbjct: 128 KAIDEFEIDLLITGIRRDEHPSRAGRRFMEVRDE-----------------------PDH 164

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK 240
             + P+  WTE DIW +I +  I    LY                               
Sbjct: 165 TLLNPILEWTEMDIWSFITMHQIPHCELYDQGY--------------------------- 197

Query: 241 KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQG 300
                 R+LGC P T                      SER GR  ++++  ++E     G
Sbjct: 198 ------RSLGCKPCTAKG-----------------GNSERDGRSAEKER--NLEQLTSMG 232

Query: 301 YF 302
           YF
Sbjct: 233 YF 234


>UniRef50_Q0W1C8 Putative 3\'-phosphoadenosine 5\'-phosphosulfate sulfotransferase
           (PAPS reductase) n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W1C8_UNCMA
          Length = 641

 Score =  178 bits (451), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 56/231 (24%), Positives = 83/231 (35%), Gaps = 35/231 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +     L+ +EA++I +IR VA +  N    + +S GKDS V+ ++ARKA          
Sbjct: 216 EANRKRLQSMEADAISVIRGVAGQHKNLPVTVSFSGGKDSLVVFNIARKAVNK----LKA 271

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN---PFVHGSAKHTDIMKTE 117
             VDTG +F E  EF +R A   G E+ V +  +          P          + K  
Sbjct: 272 FFVDTGLEFPETSEFVERFAHDTGVEITVQRAGDAFDQNFPAFGPPAKDFRWCCKVCKLG 331

Query: 118 GLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
            +   LN         G RR E   R                                  
Sbjct: 332 PITSLLNNSKGVITIDGKRRYESFQRGHIGTVER----------------------NPFV 369

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
              I VFP+ +W   ++W YI++E +   PLY        ER G  +    
Sbjct: 370 PGQIGVFPVKDWRAIEVWLYIYMEKLPYNPLYDLG----FERIGCWLCPAA 416


>UniRef50_C3MM97 Phosphoadenosine phosphosulfate reductase n=1 Tax=Sulfolobus
           islandicus L.S.2.15 RepID=C3MM97_SULIL
          Length = 301

 Score =  175 bits (443), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 66/320 (20%), Positives = 106/320 (33%), Gaps = 90/320 (28%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L      +  +I      F   V+++S GKDS++ L+ ARK       P   + +D    
Sbjct: 46  LEYKAKIAELVIEAAYNTFKRVVVVWSGGKDSTLSLYFARKVSEKLGKPLEAIIIDHYMH 105

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN--------------------------P 102
           F E ++F D   K +   L+V  N                                    
Sbjct: 106 FDETWKFIDEVKKDWNVNLIVKGNERLKGHKYGDVIKISDLSEKDRKELENVGYSKDTFL 165

Query: 103 FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
           +   +     ++KT  LK+A+ +Y  DA   G R DE  +R+ E  +S R          
Sbjct: 166 YALNNIAANHLLKTVPLKEAIEEYNIDALIVGDRWDENPARSTETFFSAR---------- 215

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
                           +  RV P+  +TE+D+W +I    + I PLY             
Sbjct: 216 -------------ENPKHFRVHPILLFTERDVWNFILTNKLPIHPLYYKG---------- 252

Query: 223 LMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQG 282
                                  FR++     T   ++          E  +  T ER G
Sbjct: 253 -----------------------FRSIDDKYETKPTDTKPA------WEQDLENTPERAG 283

Query: 283 RVIDRDQAGSMELKKRQGYF 302
           R  D++    ME+ +R GY 
Sbjct: 284 RAQDKENI--MEILRRHGYM 301


>UniRef50_Q72BR8 Phosphoadenosine phosphosulfate reductase, putative n=5
           Tax=Desulfovibrionales RepID=Q72BR8_DESVH
          Length = 255

 Score =  173 bits (438), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 67/306 (21%), Positives = 100/306 (32%), Gaps = 81/306 (26%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTL-- 56
           + +  +  L    A +  ++ EVA  +      + ++ GKDS+V L L ++         
Sbjct: 27  LRRPSVEGLELKVARARRVLLEVAHTWKPQDVAVAWTGGKDSTVALSLWQRVLDEAHPGM 86

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
               L +DTG KF E+  FRDR A+ +  +L V +   G      P           +K 
Sbjct: 87  RAKALSLDTGCKFPEVVAFRDRMAQEWSIDLTVVRPDVGPDY---PVAVDRVACCRDLKV 143

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           E L +AL +        G R DE   RA                               +
Sbjct: 144 EPLLRALKEREIAVLLTGVRADENPERASRPQTE-----------------------TFD 180

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
               +RV P+  ++E DIW Y   + +    LY                           
Sbjct: 181 APSHVRVHPVLEFSEMDIWAYTMAQGLPYCTLYAQG------------------------ 216

Query: 237 EVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELK 296
                    +R+LGC P T                 LV    ER GR  D  +  SM+  
Sbjct: 217 ---------YRSLGCVPCTS----------------LVVGGDERAGR--DATKEASMDAL 249

Query: 297 KRQGYF 302
              GYF
Sbjct: 250 HALGYF 255


>UniRef50_B1I6V6 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I6V6_DESAP
          Length = 228

 Score =  171 bits (433), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 75/306 (24%), Positives = 115/306 (37%), Gaps = 82/306 (26%)

Query: 1   MDQIRLTH--LRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTL 56
           MD+ RL +  L Q EAESI I RE    F        ++ GKDS V+LHL ++A   G +
Sbjct: 1   MDKERLFNWSLEQKEAESIRITRETLERFGTDRVATTFTGGKDSLVLLHLIKQACG-GRV 59

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
           P  +L +DT   F+E+Y F DR ++ +  +L V +N E +            +    +K 
Sbjct: 60  PVRVLKIDTSVDFKEIYAFVDRISREWNLDLHVVRNDEALKTIKT--AEDHVQCCYQLKA 117

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
             L   + ++  +A F   R DE+ +R  E   S R                        
Sbjct: 118 VPLLNFVREHSLEAVFAAIRWDEQDARKDEEYISQR-----------------------Q 154

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
             + +R+ P+ ++ E DIW YI    +    LY                           
Sbjct: 155 NPDHLRMQPILHFREIDIWSYIRKYELPFCELYRRG------------------------ 190

Query: 237 EVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELK 296
                    +R+L C P TG                     SER  R  D++   +M+  
Sbjct: 191 ---------YRSLDCEPCTGRG-----------------GASERGARSRDKE--AAMQRL 222

Query: 297 KRQGYF 302
           +  GYF
Sbjct: 223 REMGYF 228


>UniRef50_C6D4K6 Adenylylsulfate reductase, thioredoxin dependent n=2 Tax=Bacillales
           RepID=C6D4K6_PAESJ
          Length = 231

 Score =  171 bits (432), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 56/297 (18%), Positives = 99/297 (33%), Gaps = 84/297 (28%)

Query: 2   DQIRLTHLRQLE-AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           + +      +LE A    I+      F N     S G +  V++ + +K     +    +
Sbjct: 7   EALVKQKAEELENATPQEILAYAVEAFPNITFACSFGAEDVVLVDMLQKV----SPKTDI 62

Query: 61  LHVDTGWKFREMYEFRDRTAKAY-GCELLVHKN-----PEGVAMGINPFVHGSAKHTDIM 114
            ++DT + F+E YE RDR  + Y G   +  K       +    G   +   +    +I 
Sbjct: 63  FYLDTDFHFKETYETRDRMVERYPGIPFVEVKPLITPEEQAERHGAELWKSDANACCNIR 122

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E L + L+KY  DA   G RRD+  +RA  +   +  +F                   
Sbjct: 123 KVEPLTRILSKY--DAWITGIRRDQAPTRANAKKVEYDTKFG------------------ 162

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                 I+  P++ WT +D+W YI   ++   PL+                         
Sbjct: 163 -----LIKFNPIAGWTTEDVWNYIRENDVIYNPLHDQ----------------------- 194

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                      + ++GC   T  V               +     R GR   +++  
Sbjct: 195 ----------NYPSIGCEYCTRQV---------------MPGEDPRAGRWSGQEKTE 226


>UniRef50_C8WSE6 Adenylylsulfate reductase, thioredoxin dependent n=2
           Tax=Alicyclobacillus acidocaldarius RepID=C8WSE6_ALIAD
          Length = 234

 Score =  170 bits (430), Expect = 6e-41,   Method: Composition-based stats.
 Identities = 53/285 (18%), Positives = 83/285 (29%), Gaps = 83/285 (29%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           EA    I+RE      N     S G +  V+L +             + ++DT   F E 
Sbjct: 20  EARPEDILREALRRVPNITFACSFGAEDMVILDMLMSIDQQAD----VFYLDTNVLFPET 75

Query: 73  YEFRDRTAKAYGCE-LLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
           YE  +R    YG   L           +    G   +         I K E L   L   
Sbjct: 76  YELIERAVAKYGIPNLHQVLPKLTLEEQAAQYGDALWSRDPNLCCKIRKVEPLAAFLA-- 133

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           G+D    G RR++  +R   +++ +  +F                         ++V PL
Sbjct: 134 GYDGWITGIRREQAPTRRNAKVFEWDAKF-----------------------NIVKVNPL 170

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
             WTE+D+W YI    +   PL+                                    +
Sbjct: 171 VRWTEKDVWNYIVERGVPYNPLHDR---------------------------------NY 197

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
            ++GC   T  V+                    R GR    D+  
Sbjct: 198 PSIGCLHCTRPVKP---------------GEDPRSGRWAGFDKTE 227


>UniRef50_A9S2B6 Predicted protein n=3 Tax=Embryophyta RepID=A9S2B6_PHYPA
          Length = 326

 Score =  170 bits (430), Expect = 6e-41,   Method: Composition-based stats.
 Identities = 50/255 (19%), Positives = 93/255 (36%), Gaps = 38/255 (14%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +Q R   L+ LEA+++  +++    F  P    ++     V+L L  +          ++
Sbjct: 84  EQARDARLQHLEAQALETLQKTVENFEKPAFPCALIAGDVVILDLLHRIGAFSDNKVKII 143

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE-------GVAMGINPFVHGSAKHTDIM 114
            +DT   F E Y+F     + YG +  V    +           G + F+    ++  I 
Sbjct: 144 FIDTFHLFPETYKFLSEVEERYGFKAHVFHAADVNNKEAYDAKFGSDLFITDIEEYDRIC 203

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E   +AL     DA   G RRD    RA   ++                         
Sbjct: 204 KVEPFSRALKTLEVDAMINGRRRDHGAERAHLEVFE------------------------ 239

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
             +G+ ++V PL+ W  +D W Y+   ++   PL+      + +    + +  +      
Sbjct: 240 --EGKMVKVQPLAYWEFRDCWDYLTKYSLPYHPLHDQGFPSIGDVQSTIPVPREKW---- 293

Query: 235 PGEVIKKRMVRFRTL 249
             E   +R  RF+ L
Sbjct: 294 -FEYAGERSGRFQGL 307


>UniRef50_A7TD47 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7TD47_NEMVE
          Length = 320

 Score =  168 bits (424), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 88/182 (48%), Positives = 110/182 (60%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
                +L QLE E+I+I+RE AA+F NP +L+S GKDS V++HLA KAF PG  PFPL+H
Sbjct: 2   AKNNDYLEQLENEAIYILRETAAQFENPALLFSGGKDSIVLVHLALKAFRPGKFPFPLVH 61

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
           +DTG  F E   FRD      G +L+V    E +         G     + ++T  L  A
Sbjct: 62  IDTGHNFPEAIAFRDYLVNKIGEKLIVASVEESITKYNLKETPGRFPSRNALQTYALLDA 121

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           +   GFDA  GGARRDEEK+RAKERI+S RD F +WDPK QRPELW   NG+I   E   
Sbjct: 122 IQDNGFDACIGGARRDEEKARAKERIFSVRDDFGQWDPKLQRPELWDILNGKIKAIEKNN 181

Query: 183 VF 184
           V 
Sbjct: 182 VS 183


>UniRef50_D2R2B5 Phosphoadenosine phosphosulfate reductase n=5 Tax=Planctomycetales
           RepID=D2R2B5_9PLAN
          Length = 273

 Score =  167 bits (423), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 63/288 (21%), Positives = 99/288 (34%), Gaps = 84/288 (29%)

Query: 11  QLE-AESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           +LE A    I+R   A F     M  + G +  V+LH+  +         P+ ++DTG++
Sbjct: 57  ELETATPQEILRWSIARFAPKFTMATAFGPEGMVILHMLSEFA----PETPIFNLDTGYQ 112

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAM-----GINPFVHGSAKHTDIMKTEGLKQAL 123
           F E    RD  A+ YG E+ + +    V       G   + H   +     K E L++A+
Sbjct: 113 FPETLALRDEVARRYGMEVELKRATLSVEEYEAQNGGPVYRHSPDRCCHNRKVEVLEKAV 172

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G  A     RRD+   RAK  I  +  +F                         ++V
Sbjct: 173 --LGQHAWASAIRRDQSPDRAKAPIVGWDKKFG-----------------------LVKV 207

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL+NWT++ +W +I   N+   PL+                                  
Sbjct: 208 SPLANWTKKQVWTHITEHNVPYNPLHDNGYT----------------------------- 238

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
               ++GCWP T AV                    ER GR     +  
Sbjct: 239 ----SIGCWPCTRAV---------------GVGEDERAGRWSGFAKTE 267


>UniRef50_Q12WD1 Phosphoadenosine phosphosulfate reductase n=1 Tax=Methanococcoides
           burtonii DSM 6242 RepID=Q12WD1_METBU
          Length = 667

 Score =  166 bits (421), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 53/309 (17%), Positives = 96/309 (31%), Gaps = 55/309 (17%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS----NPVMLYSIGKDSSVMLHLARKAFYPGTLPF 58
              L HLR++   +++ I+ +A++         + +S GKDS V+L L   A        
Sbjct: 237 TANLPHLRKIGKNAMNTIKGIASQKEHRKLPVHVSFSGGKDSLVVLDLTLSALK--GRDV 294

Query: 59  PLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMK 115
               ++TG +F E  EF     +  G EL+  K        +    P          + K
Sbjct: 295 RAFFLNTGIEFPETVEFVHSHCENRGIELIESKAENAFWENLESFGPPAKDFRWCCKVCK 354

Query: 116 TEG----LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
                  + Q     G      G R+ E  SR+                           
Sbjct: 355 LGPAGAIIDQCSENGGVCLTIDGKRKFESFSRSNISASE--------------------- 393

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                    + +FP+ +W   ++W YI+   +D  PLY        ER G  +   +   
Sbjct: 394 -KNPFVPNQLNIFPIRDWRAIEVWLYIYWRKLDYNPLYDVG----FERVGCYLCPAELSA 448

Query: 232 DLQPGEVI-KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQA 290
           + +  + +      R+ +                L +      +S    R G    ++  
Sbjct: 449 EYERLKDLHPSIYDRWNSF---------------LLKWARSKGLSDEYVRHGMWRWKELP 493

Query: 291 GSMELKKRQ 299
             M     +
Sbjct: 494 PKMLKLASE 502


>UniRef50_D1YYA8 Putative phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocella paludicola SANAE RepID=D1YYA8_METPS
          Length = 656

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 47/234 (20%), Positives = 82/234 (35%), Gaps = 40/234 (17%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSN----PVMLYSIGKDSSVMLHLARKAFYPGTLPF 58
                 +  +E ++I++I+ V ++  N      + +S GKDS V+L+L +KA       F
Sbjct: 216 AANRKTIEAMEKDAINVIKGVVSQGKNKELPVTVSFSGGKDSLVVLNLTKKAVKK----F 271

Query: 59  PLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN---PFVHGSAKHTDIMK 115
              ++DTG +F E  +F + TAK     + + K  +          P          + K
Sbjct: 272 EAFYIDTGLEFPETTKFVEDTAKE--VPVKIEKAGKAFDENFPAFGPPAKDFRWCCKVCK 329

Query: 116 TEGLKQALNKYGFDAA-FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
              +   L+++        G RR E   R                               
Sbjct: 330 LGPVTTHLSQFKKGVITIDGKRRYESFQRGGIDTVER----------------------N 367

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
                 + VFP+ +W   ++W YI +E +    LY        ER G  +    
Sbjct: 368 PFVPGQMSVFPIKDWRAIEVWLYIHMEKLPYNELYDRG----FERIGCWLCPAA 417


>UniRef50_A1RXY7 Phosphoadenosine phosphosulfate reductase n=1 Tax=Thermofilum
           pendens Hrk 5 RepID=A1RXY7_THEPD
          Length = 614

 Score =  165 bits (418), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 62/244 (25%), Positives = 96/244 (39%), Gaps = 34/244 (13%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
              +L   EAE++  IREVA ++     +  S GKDS V LHLA KA   G      L  
Sbjct: 207 NREYLLAKEAEAVSFIREVAEKYRLPVFVSLSGGKDSLVTLHLAVKAL--GNEKVKALFN 264

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN---PFVHGSAKHTDIMKTEGLK 120
           +TG +F E  E+  R A  YG EL+     +     +    P          + K   + 
Sbjct: 265 NTGLEFEETVEYARRIADYYGVELIEADAGDNFWRALPVMGPPARDYRWCCKVTKFSTIS 324

Query: 121 QALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           +A+ K+  + A    G R+ E  +RA                    P +W NY       
Sbjct: 325 RAVKKFFPEGALSLVGQRKYESSARALS------------------PRIWRNY----WLP 362

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +   P+ +W+  DIW YI++E + +  LY        +R G  +       +L    +
Sbjct: 363 GVVAASPVHDWSAMDIWLYIFMERLPVNKLYYYG----FDRLGCWLCPASEMGELDLLRI 418

Query: 239 IKKR 242
           +K  
Sbjct: 419 VKPG 422


>UniRef50_Q2FND9 Phosphoadenosine phosphosulfate reductase n=7
           Tax=Methanomicrobiales RepID=Q2FND9_METHJ
          Length = 885

 Score =  165 bits (417), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 48/241 (19%), Positives = 79/241 (32%), Gaps = 36/241 (14%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
              HL+ LE  ++  I+    +     + +S GKDS+ +LHLARKA            +D
Sbjct: 198 NTYHLKNLERNAVRTIKSHMKDRPTVNVSFSGGKDSTAVLHLARKAGVE-----KAFFID 252

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA-MGINPFVHGSAKHTDIMKTEGLKQAL 123
           TG +F E   F +      G E++        A     P    +     ++K   LK  L
Sbjct: 253 TGLEFPETIRFIEEQ----GVEIIRKGGDFWQAVEKAGPPGKDNRWCCKLLKLHPLKIYL 308

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G      G R  E  +RA                           +        + +
Sbjct: 309 ADTGPCVTIQGNRWYESWNRAGLD----------------------ETSQNPANPLQLNI 346

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            P+ +W   +++ Y+W   I + PLY       +ER G  +       +           
Sbjct: 347 SPIRSWRAFEVFLYLWWRKIPLNPLYERG----IERIGCYLCPAMLESEYDSIRKTHPDF 402

Query: 244 V 244
            
Sbjct: 403 T 403


>UniRef50_Q1ITG5 Phosphoadenylylsulfate reductase (Thioredoxin) n=5 Tax=Bacteria
           RepID=Q1ITG5_ACIBL
          Length = 234

 Score =  164 bits (414), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 56/288 (19%), Positives = 92/288 (31%), Gaps = 79/288 (27%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
            +   A +  +++E       P +  S   +  V+L L R+         P+L +DTG+ 
Sbjct: 10  FQAKIAAAQALVQESIEHAKRPCLTCSFQAEDVVVLDLLRQVV----PDIPVLFLDTGYH 65

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN----PFVHGSAKHTDIMKTEGLKQALN 124
           F E+Y++RD  A  +   L+     + VA   +     +     +     K E L +AL 
Sbjct: 66  FAEVYQYRDEIASKWRLNLINLLPKQSVAEQESAFGILYQTAPDRCCGARKVEPLFRALE 125

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            Y     F G RR++ KSR+  +                               E  +V 
Sbjct: 126 NY--STWFTGLRREQSKSRSALQSID--------------------LFTLPTGTEIQKVS 163

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL+ W+ +D+W Y     I ++PLY                                   
Sbjct: 164 PLAEWSTRDVWTYASAHGIPLLPLYEKG-------------------------------- 191

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGS 292
            + ++GC P T                 L S    R GR         
Sbjct: 192 -YSSIGCEPCTS----------------LPSEGDPRSGRWGGHKLECG 222


>UniRef50_D1CDF4 Phosphoadenosine phosphosulfate reductase n=2 Tax=Bacteria
           RepID=D1CDF4_THET1
          Length = 248

 Score =  164 bits (414), Expect = 4e-39,   Method: Composition-based stats.
 Identities = 52/298 (17%), Positives = 93/298 (31%), Gaps = 89/298 (29%)

Query: 1   MDQIRLTHLR----QLE-AESIHIIREVAAEF-SNPVMLYS-IGKDSSVMLHLARKAFYP 53
           +++     L     +LE A    II+     F    ++  S  G     +L +A K    
Sbjct: 8   VEEPAKEELDRINAELEDATPQEIIKWAVDRFGDGLILACSFGGISGMAILDMAVKI--- 64

Query: 54  GTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNP-----EGVAMGINPFVHGSA 108
                 + ++DT + F E ++ ++   K YG + +  K       +    G   +     
Sbjct: 65  -KPDIDVFYIDTDFLFPETHQTKEEAIKRYGIKPIAFKTKLTPEAQAEKYGDELWKRNPD 123

Query: 109 KHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELW 168
               I K E  ++AL   G  A   G RRD+  +R   R   +  +F             
Sbjct: 124 LCCHIRKVEPTREALK--GRSAWITGLRRDQSSTRRNVRPVEWDYKFG------------ 169

Query: 169 HNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
                        ++ PL+ W E+++W+YI+  N+   PL+                   
Sbjct: 170 -----------LYKINPLAYWNEREVWRYIFKHNVPYNPLHDQG---------------- 202

Query: 229 NRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVID 286
                            + ++GC   T  V                 +   R GR   
Sbjct: 203 -----------------YPSIGCTHCTSPV---------------YGSEDSRAGRWAG 228


>UniRef50_C5A452 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS
           reductase), containing one PUA domain and 2 4Fe-4S
           binding domains n=9 Tax=Thermococcaceae
           RepID=C5A452_THEGJ
          Length = 634

 Score =  163 bits (413), Expect = 5e-39,   Method: Composition-based stats.
 Identities = 47/262 (17%), Positives = 86/262 (32%), Gaps = 41/262 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +     L +   +S   +R VA+++S     + +S GKDS  +L LA +        F +
Sbjct: 226 RANAIALEEKVMKSREFMRRVASKYSDLPVAVAFSGGKDSLAVLGLALE---EFGSDFTV 282

Query: 61  LHVDTGWKFREMYEFRDRTAKAY---GCELLVHKNPEGVAMGIN---PFVHGSAKHTDIM 114
              +TG +F E  E+  +  K     G + +V    +     +    P          + 
Sbjct: 283 FFNNTGIEFPETVEYVGKLRKELEPKGIKFVVADAGDAFWRALYVFSPPGRDYRWCCKVT 342

Query: 115 KTEGLKQALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           K   +  A+ +        F G R+ E   R K+                          
Sbjct: 343 KLGPITLAIKENYPKGVLMFVGQRKYESIKRFKQPRV----------------------W 380

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
                   I   P+ +W   ++W YI+   +   PLY        +R G  +    +  +
Sbjct: 381 RNEWVPNEIGASPIFHWRAIEVWLYIFSRKLPYNPLYERG----FDRIGCFLCPSASLAE 436

Query: 233 LQ--PGEVIKKRMVRFRTLGCW 252
            +    E  +     F+ L  W
Sbjct: 437 FERLKREKPELWEKWFKALEYW 458


>UniRef50_C5U5U5 Phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocaldococcus infernus ME RepID=C5U5U5_9EURY
          Length = 395

 Score =  162 bits (410), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 52/227 (22%), Positives = 84/227 (37%), Gaps = 35/227 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           +     + +LE ++ ++I+    +       +S GKDSSV   LA +          ++ 
Sbjct: 145 KKNKNRIEKLEKKAKNLIKNY--KGKEINASFSGGKDSSVSTLLANEIIK----DIEVIF 198

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGLK 120
           +DTG +F E  +F    AK Y   L + K  +              +     I K   L+
Sbjct: 199 IDTGLEFPETIKFVKDFAKKYDLNLTILKGGDFWEELNKRGVPTKDNRWCNTICKLNPLR 258

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           + L KY       G+RR E  SR +                        +Y  +      
Sbjct: 259 EYLKKYKLVYTINGSRRAESFSRERL-----------------------SYEKRGLIENQ 295

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
           I VFP+ +W   D+W +I+L +I   PLY        ER G  +   
Sbjct: 296 INVFPILDWKGVDVWSWIYLNDILYNPLYDKG----FERIGCYLCPA 338


>UniRef50_D1YW88 Putative phosphoadenosine phosphosulfate reductase n=1
           Tax=Methanocella paludicola SANAE RepID=D1YW88_METPS
          Length = 632

 Score =  162 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 54/250 (21%), Positives = 86/250 (34%), Gaps = 36/250 (14%)

Query: 4   IRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
               +L  +E E+I   ++VA ++     + YS GKDS   L L RKA       F +L+
Sbjct: 222 ANREYLMSIEGEAIGFAKKVAGQYRLPVTVSYSGGKDSLATLLLVRKAL----PDFDVLY 277

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGLK 120
           ++TG +F E  +        YG  L   K       A  + P    +     + K   + 
Sbjct: 278 INTGLEFPETTQNVHDVVAQYGLRLKTAKAGSFWDAAPSLGPPSVEARWCCKVCKLGPIT 337

Query: 121 QALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
             +     D    F G RR E + RAK                                G
Sbjct: 338 DLIENNYSDGCLTFIGQRRYESEVRAK----------------------SQRIWQNPWVG 375

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +   P+ +WT   IW Y++ E     PLY        +R G  +    +  D +  + 
Sbjct: 376 NQVSASPIQHWTALHIWLYLFREKAPYNPLYGRG----FDRIGCWLCPSASLADYEFVKS 431

Query: 239 I-KKRMVRFR 247
              +   R+ 
Sbjct: 432 QYPEMWARWE 441


>UniRef50_Q60377 Uncharacterized protein MJ0066 n=5 Tax=Methanocaldococcus
           RepID=Y066_METJA
          Length = 480

 Score =  162 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 46/246 (18%), Positives = 84/246 (34%), Gaps = 34/246 (13%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           M +     +   E  +I  I+    +   PV + +S GKDS V L L  KA         
Sbjct: 228 MVRANEGVIDNYERNAIGFIKNTYEKIKKPVMVAFSGGKDSLVTLILTLKAL---GKDID 284

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTE 117
           ++ +DTG +F E  +  +   + YG +++  +                     ++I K E
Sbjct: 285 VVFIDTGLEFEETLKNVEDVERHYGIKIIRLRGENFWEKVKEYGIPARDYRWCSEICKLE 344

Query: 118 GLKQALNKYGFD--AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQI 175
            LK+ + +   D   +F G R+ E  +RA ++                            
Sbjct: 345 PLKKFIEENYEDDVLSFVGIRKYESFNRATKKRIHRNTYIK------------------- 385

Query: 176 NKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
              + I   P+ +W+   +W Y+  E      LY        +R G  M       ++  
Sbjct: 386 ---KQINALPIFHWSSLHVWIYLLREKAPYNKLYEKG----FDRIGCFMCPAMEMGEMNK 438

Query: 236 GEVIKK 241
            +    
Sbjct: 439 IKREFP 444


>UniRef50_Q0W3A3 Putative 3\'-phosphoadenosine 5\'-phosphosulfate sulfotransferase
           (PAPS reductase) n=1 Tax=uncultured methanogenic
           archaeon RC-I RepID=Q0W3A3_UNCMA
          Length = 627

 Score =  162 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 50/237 (21%), Positives = 79/237 (33%), Gaps = 35/237 (14%)

Query: 3   QIRLTHLRQLEAESIHIIRE-VAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
                ++   E+E I   +   A +     + YS GKDS   L + RKA       F ++
Sbjct: 214 AANANYIDGFESEGISFAKRVAAEKNLPVTVSYSGGKDSLATLLIVRKAL----PDFDVM 269

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEGL 119
           +++TG +F E        A+ Y  +L V +       A    P    +     + K   +
Sbjct: 270 YINTGLEFPETTANVHEVAEKYQLKLKVAEAESFWAAAPKFGPPSVEARWCCKVCKLGPI 329

Query: 120 KQALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
              +     +    F G RR E + RAK                                
Sbjct: 330 TDLIENSYPEGCLSFIGQRRYESEVRAKSLRV----------------------WQNPWV 367

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
           G  I   P+ NWT   IW Y++ E     PLY        +R G  +    +  D +
Sbjct: 368 GNQISASPIQNWTALHIWLYLFREKAPYNPLYERG----FDRIGCWLCPSASLADYE 420


>UniRef50_A2SQI0 Phosphoadenosine phosphosulfate reductase n=3
           Tax=Methanomicrobiales RepID=A2SQI0_METLZ
          Length = 472

 Score =  161 bits (407), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 62/252 (24%), Positives = 90/252 (35%), Gaps = 42/252 (16%)

Query: 4   IRLTHLRQLEAESIHIIREVAAEFSNP--VMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
                L   E +SI  I +V A+       + YS GKDS V L +  KA     L  PL+
Sbjct: 214 ANNNILDLYERKSIEFIHDVIAKNPGIQPTVSYSGGKDSLVTLLITLKA----GLRLPLI 269

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEG 118
             DTG +F E  E   + ++ +   L++     G   G     P            K   
Sbjct: 270 FADTGLEFPETIENVQKVSELFDLPLIIESGNSGFWEGFELQGPPAVDFRWCCKACKLTP 329

Query: 119 LKQAL-NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
           +K  + NK+G   +F G R+ E   R                   Q P +W N N     
Sbjct: 330 VKTLIENKWGEAISFIGQRKFESAKRM------------------QSPRVWRNRNV---- 367

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
              I   P+ +WT    W Y++ E     PLY       L+R G  M    +   ++  E
Sbjct: 368 PCQISAAPIQHWTAMHDWLYLFREKAPYNPLYELG----LDRIGCFMCPSSDIACMKDIE 423

Query: 238 VIKKRMVRFRTL 249
                  R+  L
Sbjct: 424 ------ARYPEL 429


>UniRef50_Q55309 Phosphoadenosine phosphosulfate reductase n=3 Tax=Bacteria
           RepID=CYSH_SYNE7
          Length = 232

 Score =  161 bits (406), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 51/258 (19%), Positives = 91/258 (35%), Gaps = 47/258 (18%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           +  +   + +  +  +  II+  A EF    V+  S G  S+VMLHLA +         P
Sbjct: 5   LPSLTEINAQLADQAATQIIQWAATEFGSGLVLSTSFGIQSAVMLHLATQV----QPDIP 60

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVH--------GSAKHT 111
           ++ +DTG+   E Y F     +     L V+++    A     +             ++ 
Sbjct: 61  VIWIDTGYLPTETYRFAAELTERLKLNLKVYQSEISPARMEALYGRLWESESVEDFNRYD 120

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            + K E + +AL + G  A   G RR +   R    I                       
Sbjct: 121 QMRKVEPMNRALQELGATAWLSGVRRQQTAHRQSMEIVEL-------------------- 160

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                K +   + P+  W  +D++QY+   ++   PL+      V +      +  D+  
Sbjct: 161 -----KRDRYAIRPILGWHSRDVYQYLTAHDLPYHPLFDQGYVTVGDWHSSRPLQADD-- 213

Query: 232 DLQPGEVIKKRMVRFRTL 249
                    +R  RFR L
Sbjct: 214 -------SDERSTRFRGL 224


>UniRef50_Q12UR6 Phosphoadenosine phosphosulfate reductase fused to RNA-binding PUA
           and 4Fe-4S binding domains n=3 Tax=Methanosarcinaceae
           RepID=Q12UR6_METBU
          Length = 633

 Score =  160 bits (405), Expect = 4e-38,   Method: Composition-based stats.
 Identities = 48/237 (20%), Positives = 74/237 (31%), Gaps = 36/237 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
                 L   E ++   I+  +   + PV + YS GKDS  +L L  +        + LL
Sbjct: 222 NANSKILEHFEDKAHQFIKHTSKTVNRPVSVSYSGGKDSLAVLQLVSECLD----DYELL 277

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMG---INPFVHGSAKHTDIMKTEG 118
             DTG +F E  E      + Y   L      E          P    +     + K   
Sbjct: 278 FADTGLEFPETIENVKEIVEHYQRPLRTKDVGEAFWESVGDFGPPSVEARWCCKVCKLGP 337

Query: 119 LKQALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           + Q +N    D    F G R+ E  +RA                                
Sbjct: 338 ISQIINDNYEDGCLTFIGQRKYESAARANSERV----------------------WKNPW 375

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
            G  I   P+ +WT   +W YI+   +    +Y        +R G  +    +  DL
Sbjct: 376 VGNQIGASPIQDWTAMHVWLYIFKTGVPYNVMYERG----FDRIGCWLCPSSSLSDL 428


>UniRef50_Q58383 Uncharacterized protein MJ0973 n=11 Tax=Methanococcales
           RepID=Y973_METJA
          Length = 411

 Score =  160 bits (404), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 54/240 (22%), Positives = 84/240 (35%), Gaps = 36/240 (15%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSN----PVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
               + +LE +S+ II++      N        +S GKDSSV   LA K          +
Sbjct: 152 NKDRIEKLEKKSLSIIKKYYEMCKNKNYAINTSFSGGKDSSVSTLLANKVID----DLEV 207

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMKTEG 118
           + +DTG +F++  +F  + AK Y   L+V K                       + K E 
Sbjct: 208 IFIDTGLEFKDTIDFVKKFAKKYDLNLVVLKGKNFWEYLEKEGIPTKDYRWCNSVCKLEP 267

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           LK+ L KY       G+RR E  +R K                                 
Sbjct: 268 LKEYLKKYKRVYTIDGSRRYESFTREKLTYER----------------------KSGFIE 305

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             I +FP+ +W   D+W +I+L ++    LY        ER G  M       +    + 
Sbjct: 306 NQINIFPILDWRGTDVWSWIYLNDVIYNELYDKG----FERIGCYMCPAALNAEFLRVKE 361


>UniRef50_D1I5Z9 Whole genome shotgun sequence of line PN40024,
           scaffold_59.assembly12x (Fragment) n=20 Tax=cellular
           organisms RepID=D1I5Z9_VITVI
          Length = 467

 Score =  160 bits (404), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 55/290 (18%), Positives = 92/290 (31%), Gaps = 80/290 (27%)

Query: 9   LRQLE-AESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            + LE A  + I+ +    F N   + +S G +  V++    +       PF +  +DTG
Sbjct: 92  AKDLESASPLEIMDKALQNFGNDIAIAFS-GAEDVVLI----EYARLTGRPFRVFSLDTG 146

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV---HGSAKHTDIMKTEGL 119
               E Y F D   K YG  +          + +      F     G  +   I K   L
Sbjct: 147 RLNPETYAFFDTVEKHYGIHIEYVFPDSVEVQALVRNKGLFSFYEDGHQECCRIRKVRPL 206

Query: 120 KQALNKYGFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           ++AL   G  A   G R+D+   +RA+  +      F   D                  G
Sbjct: 207 RKALK--GLRAWITGQRKDQSPGTRAEIPVVQVDPTFEGMDS---------------GVG 249

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             ++  P++N    DIW ++   N+ +  L+                             
Sbjct: 250 SLVKWNPVANVDSMDIWNFLRAMNVPVNSLHSQG-------------------------- 283

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRD 288
                  + ++GC P T  V               +    ER+GR    D
Sbjct: 284 -------YVSIGCEPCTRPV---------------LPGQHEREGRWWWED 311


>UniRef50_A9AB03 Phosphoadenosine phosphosulfate reductase n=7 Tax=Methanococcus
           RepID=A9AB03_METM6
          Length = 512

 Score =  160 bits (404), Expect = 7e-38,   Method: Composition-based stats.
 Identities = 55/241 (22%), Positives = 93/241 (38%), Gaps = 33/241 (13%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           M +     ++++E+ SI  +R    +   P  + YS GKDS  +L LA +AF     P  
Sbjct: 240 MIEANKNAMQKVESNSIGFMRNTVVKIGRPASVAYSGGKDSLTVLLLALEAFKNHEDPIE 299

Query: 60  --LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE--GVAMGINPFVHGSAKHTDIMK 115
             +L  DTG +F E  E  ++ AK YG E+L   + E         P    +   +++ K
Sbjct: 300 FNVLFNDTGIEFNETLENIEKIAKLYGIEILKTSSGEFWEKLEEYGPPGRDNRWCSEVCK 359

Query: 116 TEGLKQALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
              L   +++        F G R+ E  +R+K                  +P +W+    
Sbjct: 360 VSPLGTLIDEKYEKGCLSFVGLRKYESINRSK------------------KPRIWN---- 397

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
                + +   P+ NWT   +W YI         LY        +R G  M       ++
Sbjct: 398 SPTIKKQMLSAPILNWTAMHVWIYILKHKAPYNVLYEQC----FDRVGCFMCPAMEIGEI 453

Query: 234 Q 234
           +
Sbjct: 454 E 454


>UniRef50_C7NUQ7 Phosphoadenosine phosphosulfate reductase n=12 Tax=Halobacteriaceae
           RepID=C7NUQ7_HALUD
          Length = 325

 Score =  160 bits (404), Expect = 7e-38,   Method: Composition-based stats.
 Identities = 62/331 (18%), Positives = 120/331 (36%), Gaps = 71/331 (21%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPF-PLLHVDTGW 67
           +     ++I + +    ++ NPV++++ GKDS++ L+  ++      L   P++ +D   
Sbjct: 29  IEHQIEKAIEVTKTGLEQYDNPVVMWTGGKDSTLTLYFVKEVADRFDLEVPPVVFIDHYQ 88

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPE--------------------------------- 94
            F E+ +F    A+ +  E++  +N +                                 
Sbjct: 89  HFDELIDFCKHWAEEWDLEIIWARNTDVGDYVDENGLEPGDDIPVDALSEHNQHHIRNIL 148

Query: 95  GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDR 154
                  PF+  +     ++KT  L  A+ ++  D    G R DE+++RA E  +S R  
Sbjct: 149 EYEEDTFPFLLDTYVGNHLLKTVALNDAIEEHDVDGILSGVRWDEQEARADETFFSPR-- 206

Query: 155 FHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAER 214
                            +         R+ P+  + E D+W+  W   +           
Sbjct: 207 -----------------HDPDIYPPHDRIQPILQFAEADVWEAFWNFVVP-------DTV 242

Query: 215 PVLERDGMLMMIDDNRIDLQPGEV---IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEE 271
                +G +    ++  D    E      K    FR+LG    T      A   P  +++
Sbjct: 243 EEFPEEGYVPQGSEDLPDGLTKEDVPVSPKYFAGFRSLGSEVST----DKAAEEPAWLQD 298

Query: 272 MLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           M  + T+ER GR  D++    ME  +  GY 
Sbjct: 299 M--ANTTERAGRAQDKEDL--MERLRDLGYM 325


>UniRef50_D0LSJ1 Phosphoadenosine phosphosulfate reductase n=1 Tax=Haliangium
           ochraceum DSM 14365 RepID=D0LSJ1_HALO1
          Length = 285

 Score =  159 bits (402), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 57/290 (19%), Positives = 93/290 (32%), Gaps = 82/290 (28%)

Query: 11  QLE-AESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           +LE A    I+    A F     +  + G +   +LH+A +          +  +DTG+ 
Sbjct: 49  ELERATPQEILAFALASFAPRVAISTAFGVEGCALLHMAVQI----DPSVRVFTIDTGYL 104

Query: 69  FREMYEFRDRTAKAYGCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           F E  +  +R  +  G E+           +    G   +   S     + K E  ++AL
Sbjct: 105 FDETQQLIERMRERLGIEIETFHPELSVAEQDERYGEALYTRDSDACCAMRKVEPTQRAL 164

Query: 124 NKYGFDAAFGGARRDEEKS-RAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
              G DA   G RRD+  + RA+  I                         + +    I+
Sbjct: 165 R--GLDAWIAGLRRDQGGATRAQLAILE--------------------RYQRGDAEPLIK 202

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           V PL+NW   D W+Y+    +   PL     +                            
Sbjct: 203 VHPLANWNRSDTWRYVLDNEVPYNPLLDQGYK---------------------------- 234

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGS 292
                ++GCWP T AV ++A                ER GR   +     
Sbjct: 235 -----SIGCWPCTRAVGADA---------------DERAGRWGGKKAECG 264


>UniRef50_A4WMI9 Phosphoadenosine phosphosulfate reductase n=5 Tax=Thermoproteaceae
           RepID=A4WMI9_PYRAR
          Length = 594

 Score =  158 bits (399), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 51/237 (21%), Positives = 81/237 (34%), Gaps = 36/237 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           ++   H+ +   E++  I+ VA ++    V+ YS GKDS V L L  +      L F + 
Sbjct: 203 ELNREHIERRAQEAVEFIKAVAEKYKKPVVVSYSGGKDSLVALDLTAR----SGLKFYVY 258

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA---MGINPFVHGSAKHTDIMKTEG 118
             DTG +  E YE      + YG E++V    +          P          ++K   
Sbjct: 259 FNDTGLEPPETYENLKAVEERYGVEVIVGAAGQRFWEAMEKFGPPARDYRWCCKVIKLGP 318

Query: 119 LKQALNKYGFDAAF--GGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
             +AL            G R  E   RAK    S                          
Sbjct: 319 TTEALKSRFPQGYISVVGQRGAESFVRAKTPRVSP----------------------SKW 356

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
              S+   PL  WT  ++W YI+L  +     Y        +R G ++   +   +L
Sbjct: 357 VAGSVVAAPLQEWTALEVWLYIFLHKLPYNRAYERG----FDRLGCVVCPANEMAEL 409


>UniRef50_Q5HKZ5 Phosphoadenosine phosphosulfate reductase n=110 Tax=Bacillales
           RepID=CYSH_STAEQ
          Length = 243

 Score =  158 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 51/295 (17%), Positives = 92/295 (31%), Gaps = 84/295 (28%)

Query: 4   IRLTHLRQLEAESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           I    +      +  I++     + N  V   S G +S V++ L  +          ++ 
Sbjct: 17  INELDINDETKGAYEILKWAYQTYENDIVYSCSFGAESMVLIDLISQI----KPDAQIVF 72

Query: 63  VDTGWKFREMYEFRDRTAKAY-GCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKT 116
           +DT   F+E Y+  DR    Y    + + K       +G       + +   +   I K 
Sbjct: 73  LDTDLHFQETYDLIDRVKDKYPQLRIKMKKPELTLEEQGEKYNPALWKNDPNQCCYIRKI 132

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           + L+  L+  G  A   G RR +  +RA     +  +RF                     
Sbjct: 133 KPLEDVLS--GAVAWISGLRRAQSPTRAHTNFINKDERFKS------------------- 171

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
               I+V PL  WTE+++W YI  +++    L+                           
Sbjct: 172 ----IKVCPLIYWTEEEVWSYIRDKDLPYNELHDQ------------------------- 202

Query: 237 EVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                    + ++GC P T  V                 +   R GR  +  +  
Sbjct: 203 --------NYPSIGCIPCTSPV---------------FDSNDSRAGRWSNSSKTE 234


>UniRef50_B5IFS1 Phosphoadenosine phosphosulfate reductase n=2 Tax=Aciduliprofundum
           boonei T469 RepID=B5IFS1_9EURY
          Length = 580

 Score =  157 bits (397), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 44/252 (17%), Positives = 80/252 (31%), Gaps = 36/252 (14%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +  + HL  +E  ++  IRE    +     + +S GKDS  +L LA K      + F   
Sbjct: 215 EANIQHLENIENRAVKFIRETKMRYDLPLAVSFSGGKDSLAVLLLALK----SGMDFHTF 270

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA---MGINPFVHGSAKHTDIMKTEG 118
            ++TG +  E  E+ +   K YG ++                 P          + K   
Sbjct: 271 FLNTGIELPETVEYVNEIEKKYGIKMDRIDAGNAFWGSLEHFGPPGRDYRWCCKVTKLGP 330

Query: 119 LKQALNKYGFDAAFG--GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
             + + +          G RR E   R +                  +  +W N      
Sbjct: 331 TTKYILENYPSGLLTLIGQRRYESMERMR------------------KGNIWRN----EW 368

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
               +   P+ NW+  ++W YI  +   I   Y       L R G  +    +  D +  
Sbjct: 369 VPNQLSASPIQNWSSLEVWLYILWKRAPINVWYKRG----LTRIGCYLCPSSDLADFEIV 424

Query: 237 EVIKKRMVRFRT 248
                 +  + +
Sbjct: 425 GKYFDGIDGWFS 436


>UniRef50_Q2S5G4 Phosphoadenosine phosphosulfate reductase n=2 Tax=Bacteria
           RepID=CYSH_SALRD
          Length = 252

 Score =  156 bits (395), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 45/282 (15%), Positives = 87/282 (30%), Gaps = 82/282 (29%)

Query: 16  SIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
              I+      F  +       G    V++H+             + ++DT   F E YE
Sbjct: 29  PKAILNWATHTFGDDLAQGTGFGPSGIVIMHMLA----DLRPGTTVFYLDTDLLFPETYE 84

Query: 75  FRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
             D   +    ++           +    G   +     +   + K + L+  L+     
Sbjct: 85  LCDDLDERLDVDVTRVHGGLSLDEQAEQEGEELWNRNPNRCCFLRKVKPLRNFLDDR--R 142

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
           A   G RRD+ + RA   I S+  ++                          ++ PL+NW
Sbjct: 143 AWITGVRRDQSERRADTDILSWEGQYG-----------------------VFKINPLANW 179

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
           T++++W+Y++  ++   P +                                    + +L
Sbjct: 180 TQKEVWKYLFEHDLPYNPKHDQG---------------------------------YPSL 206

Query: 250 GCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           GC P T  V+               +    R+GR  DRD+  
Sbjct: 207 GCVPCTEPVD--------------QADGYSREGRWSDRDKTE 234


>UniRef50_B0T3S8 Phosphoadenosine phosphosulfate reductase n=7
           Tax=Alphaproteobacteria RepID=B0T3S8_CAUSK
          Length = 258

 Score =  156 bits (395), Expect = 6e-37,   Method: Composition-based stats.
 Identities = 53/288 (18%), Positives = 93/288 (32%), Gaps = 84/288 (29%)

Query: 10  RQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
              +A  + ++R+    F     ++ S G +S+V+LHLA +     +   P+L +DTG  
Sbjct: 30  ELRDAHPLTVLRKAYETFGDKLALVSSFGAESAVLLHLASQV----SKDIPVLFLDTGML 85

Query: 69  FREMYEFRDRTAKAYGC----ELLVHKNPEGV-AMGINPFVHGSAKHTDIMKTEGLKQAL 123
           F +  ++R   A   G     +L        V     + +   +     I K   L +AL
Sbjct: 86  FGQTLDYRKSLAAKLGLTDVRDLRPAYTDLAVTDPKSDLWRTDTDACCHIRKVLPLDRAL 145

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
            +  F A   G +R     R + R+                                I+ 
Sbjct: 146 GE--FAAWTTGRKRFHGGDRLRLRVVE-------------------------ETQGQIKF 178

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL+NW + ++  Y+   ++   PL                                   
Sbjct: 179 NPLANWGKAELDAYVAEYDLPAHPLVSQG------------------------------- 207

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
             F ++GCWP T  V+  A  +              R GR   +D+  
Sbjct: 208 --FPSVGCWPCTKPVDDPAADV--------------RAGRWAGQDKTE 239


>UniRef50_Q1GFS4 Phosphoadenylylsulfate reductase (Thioredoxin) n=17
           Tax=Rhodobacterales RepID=Q1GFS4_SILST
          Length = 253

 Score =  156 bits (394), Expect = 8e-37,   Method: Composition-based stats.
 Identities = 48/293 (16%), Positives = 93/293 (31%), Gaps = 80/293 (27%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +Q+   + R     +  ++     +  N  ++ S G +S V+LH+A           P+L
Sbjct: 23  EQVAALNARFKHHSATSVMEGALRDAGNIALVSSFGAESVVLLHMAAVI----DPSVPVL 78

Query: 62  HVDTGWKFREMYEFRDRTAKAYGC-ELLVHKNPEGVAMGINPFVH--GSAKHTDIMKTEG 118
            VDT   F E   ++   ++  G   + V K  +         +    +     + KT  
Sbjct: 79  FVDTELLFTETLVYQQEVSERLGLRNVHVIKADDIAEKDPYGAMRFSDTDACCTLRKTIP 138

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L++AL   G+D    G +R +  +RA    +   D   R                     
Sbjct: 139 LQKALA--GYDGWITGRKRFQSGTRAALDFFEVEDGTGR--------------------- 175

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +++ PL++W  +D+  Y+    +   PL                              
Sbjct: 176 --MKINPLAHWAPEDVRAYMDENRLPRHPLVAKG-------------------------- 207

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                  + ++GC P T  V                     R GR  ++++  
Sbjct: 208 -------YPSIGCEPCTSPVA---------------EGEDPRAGRWRNQNKEE 238


>UniRef50_D2EEN4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Parvarchaeum acidiphilum ARMAN-4 RepID=D2EEN4_9EURY
          Length = 276

 Score =  155 bits (392), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 68/322 (21%), Positives = 117/322 (36%), Gaps = 92/322 (28%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPF-PLLHVDTGW 67
           L   E  ++ +I++    ++ P +++S GKDS+V+L L R+A     +   P L +D G 
Sbjct: 19  LEAKEDIALIVIKDALKRYNRPTVVWSAGKDSTVVLDLVRRACKDLGMQLPPALFIDHGQ 78

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAM----------GINPFVHGSAKH------- 110
            + E  +  +  +K +G +++  KN + +             +N      AK        
Sbjct: 79  HYDETMKMLEDISKGWGFKMVYAKNEDVIKNVGKDNKIKLSSLNKINQDEAKRIGFNGEE 138

Query: 111 ----------TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP 160
                       ++KT  +  A+ KY FDA F G R DE ++R+ E   S R        
Sbjct: 139 FEYSLETEIGNHLLKTVAMNMAIEKYRFDALFTGVRWDENEARSTEVFISPRT------- 191

Query: 161 KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
                             + +RV P+  + E+++W+YI+   +   PLY    R +  + 
Sbjct: 192 ----------------HPDHVRVQPILPFAERNVWEYIFKYKLPTHPLYKLGYRSIDGKL 235

Query: 221 GMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSER 280
                                                       LP    E  +  T ER
Sbjct: 236 D-------------------------------------SKKTSDLPAW--EQDLEHTKER 256

Query: 281 QGRVIDRDQAGSMELKKRQGYF 302
            GR  D++  G ME  +  GY 
Sbjct: 257 AGRSQDKE--GVMEKLRLFGYM 276


>UniRef50_C5QND2 Phosphoadenosine phosphosulfate reductase n=5 Tax=Bacillales
           RepID=C5QND2_STAEP
          Length = 244

 Score =  155 bits (392), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 47/283 (16%), Positives = 86/283 (30%), Gaps = 84/283 (29%)

Query: 16  SIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           +  I+      +  + V   S G +S V++ L  +          ++ +DT   F+E Y+
Sbjct: 30  AYQILNWAYKTYGDDIVYSCSFGAESMVLIDLISQI----KPDAQIVFLDTDLHFQETYD 85

Query: 75  FRDRTAKAY-GCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
             DR    Y    + + K       +        + +   +   I K + L++ L   G 
Sbjct: 86  LIDRVRDKYPQLRIKMKKPELTLEEQAEKYNPALWKNNPNQCCYIRKIKPLEEVL--TGA 143

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
            A   G RR +  +RA     +  +RF                          +V PL  
Sbjct: 144 VAWVSGLRRAQSPTRASTDFINKDERFKSV-----------------------KVCPLIY 180

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           WTE ++W YI   ++    L+                                    + +
Sbjct: 181 WTEDEVWDYIKSNDLPYNELHDQH---------------------------------YPS 207

Query: 249 LGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           +GC P T  V                 +   R GR  + ++  
Sbjct: 208 IGCIPCTAPV---------------FDSNDSRAGRWSNFEKTE 235


>UniRef50_C6P7J4 Adenylylsulfate reductase, thioredoxin dependent n=1
           Tax=Sideroxydans lithotrophicus ES-1 RepID=C6P7J4_9PROT
          Length = 265

 Score =  154 bits (390), Expect = 2e-36,   Method: Composition-based stats.
 Identities = 51/291 (17%), Positives = 82/291 (28%), Gaps = 86/291 (29%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
             L      +I ++ + A EF+  V   S+G +  V+  L  K          +  +DTG
Sbjct: 3   EELTGKIEATIAVLHQAANEFAPVVFASSLGAEDMVLTDLIAK----HRPDIQMFSLDTG 58

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAM---------GINPFVHGSAKHTDIMKTE 117
              +E Y+        Y   L ++     +           G    V        + K E
Sbjct: 59  RLPKETYDLMQEVRLRYSVPLTIYFPDGKLVEDYVAQHGINGFYDSVENRKGCCFVRKVE 118

Query: 118 GLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
            L++AL   G  A   G RRD+  +R    + +F                          
Sbjct: 119 PLRRALA--GKGAWITGMRRDQAVTRGTLAVSAFDVDNG--------------------- 155

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
               +  PL  W+  D+W YI   ++    L+                            
Sbjct: 156 --LQKFNPLLEWSHNDVWTYIRQHDVPYNKLHDQF------------------------- 188

Query: 238 VIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRD 288
                   + +LGC P T +V                     R GR    D
Sbjct: 189 --------YPSLGCAPCTRSV---------------TPGEDIRAGRWWWED 216


>UniRef50_A7NG75 Phosphoadenosine phosphosulfate reductase n=2 Tax=Chloroflexi
           (class) RepID=A7NG75_ROSCS
          Length = 238

 Score =  154 bits (389), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 45/269 (16%), Positives = 83/269 (30%), Gaps = 70/269 (26%)

Query: 10  RQLEAESIH-IIREVAAEF-SNPVMLYSI-GKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            Q E +    ++   A  F     +  S  G    V+L +  +      L  P++ +DT 
Sbjct: 21  EQFETQPPEALLTWAAHMFCPRVALTCSFSGPSGMVLLDMVARL----NLDIPVVFLDTD 76

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTEGLKQ 121
             F E YE      + YG  +   +       +    G   +     +   + K   L +
Sbjct: 77  LLFPETYELVAIAERRYGIPIRRRRPVLSVEEQDRQEGPQLYARDPDRCCQVRKVAPLAE 136

Query: 122 ALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
            L  Y  DA   G RRD+  +RA   +  +  R+                         +
Sbjct: 137 TLRTY--DAWISGIRRDQSDTRATIDLLEWNTRY-----------------------NLV 171

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
           ++ PL+ WT++ +W YI    +   PL                                 
Sbjct: 172 KISPLAFWTDRQVWAYIHHHQVPYNPLLDRG----------------------------- 202

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEIIE 270
               + ++GC P T   +++       + 
Sbjct: 203 ----YPSIGCLPCTRPADASDPRAGRWVG 227


>UniRef50_B0C9W9 Phosphoadenosine phosphosulfate reductase n=1 Tax=Acaryochloris
           marina MBIC11017 RepID=B0C9W9_ACAM1
          Length = 242

 Score =  154 bits (388), Expect = 5e-36,   Method: Composition-based stats.
 Identities = 52/299 (17%), Positives = 91/299 (30%), Gaps = 84/299 (28%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           +DQ+    L +  A    I+           +   + G    V++ L  K   P     P
Sbjct: 15  IDQLN-QQLDK--AHPKSILTWCLENLPEGLIQSTAFGASGMVIMDLLYKDLNP-NPSIP 70

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKN-------PEGVAMGINPFVHGSAKHTD 112
           +L +DT   F E  +  +     YG +L + +              G   +     +   
Sbjct: 71  VLFLDTLHHFPETLKLANDAQAHYGVDLQIFRPQGVTSRAEFAQHYGEQLWETDLEQFHQ 130

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           + K E L++ L +        G RRD+  +RAK  I+                       
Sbjct: 131 LTKVEPLRRGLEQLQVATWITGRRRDQSSTRAKMPIFE---------------------- 168

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
              ++   ++V PL+NW+ +D+W Y+    +   PLY                       
Sbjct: 169 --CDRDGRLKVNPLANWSYKDVWNYLVNNQVLYNPLYDQG-------------------- 206

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                        + ++G  PLT                M      ER GR   + +  
Sbjct: 207 -------------YASIGDEPLTT---------------MTKPGEEERAGRWRGKARTE 237


>UniRef50_Q467V4 Phosphoadenosine phosphosulfate reductase n=3 Tax=Methanosarcina
           RepID=Q467V4_METBF
          Length = 796

 Score =  153 bits (387), Expect = 5e-36,   Method: Composition-based stats.
 Identities = 45/246 (18%), Positives = 72/246 (29%), Gaps = 50/246 (20%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS----NPVMLYSIGKDSSVMLHLARKAFYPGTLPF 58
           +    HL+ L   +I+ IR + +          + +S GKDS V+L LAR +        
Sbjct: 360 KANKKHLQVLGKNAINTIRGIISRKEHKNLPVYVSFSGGKDSLVVLDLARSSLKQR--EL 417

Query: 59  PLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAM---GINPFVHGSAKHTDIMK 115
               ++TG +F E  EF     +     L+                P          + K
Sbjct: 418 KAFFLNTGIEFPETVEFVRNFCREREIPLVEANAGSTFREQVGKFGPPAKDFRWCCKVCK 477

Query: 116 TEGLKQALNKYGFDA-------------AFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
                    + G  A                G R+ E  SRA+                 
Sbjct: 478 LASAGDF--ELGKGASSQKGAIGGVAYLTVDGKRKHESFSRARIAASE------------ 523

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
                             + +FP+ +W   ++W YI    +   PLY        ER G 
Sbjct: 524 ----------TNPFVPAQLNIFPIRDWKAIEVWLYIHWRQLPYNPLYDLG----FERVGC 569

Query: 223 LMMIDD 228
            +    
Sbjct: 570 WLCPSA 575


>UniRef50_A2BN02 Phosphoadenosine phosphosulfate reductase n=1 Tax=Hyperthermus
           butylicus DSM 5456 RepID=A2BN02_HYPBU
          Length = 451

 Score =  153 bits (386), Expect = 7e-36,   Method: Composition-based stats.
 Identities = 48/243 (19%), Positives = 82/243 (33%), Gaps = 38/243 (15%)

Query: 1   MDQIRLTHLRQ---LEAESIHIIREVAAEF----SNPVMLYSIGKDSSVMLHLARKAFYP 53
           M++    +      L +E+   IR V A +        + +S G DS+ +L LAR+A  P
Sbjct: 190 MEEAVEVNAEVVGGLASEAREFIRRVYARYQASRGRLYVAFSGGSDSATVLSLAREAVGP 249

Query: 54  GTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA---MGINPFVHGSAKH 110
                  ++VDTG +F E   + ++     G +L V +                      
Sbjct: 250 EN--VVAVYVDTGMEFPETRRYVEKVTSILGVDLEVVEAEAEPIEEIRRRGLMTRDDRWC 307

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
           T ++K + L++     G      GARR E  +RA                          
Sbjct: 308 TRLLKLKPLRRFYRSRGVRLILDGARRWESTTRASTPRI--------------------- 346

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
                     +R  P+ +W    +  Y++   I    LY       L R G +     + 
Sbjct: 347 -GENPLIPGVVRALPIHHWPRLAVQLYLYERGIPFNHLYSKG----LTRIGCISCPAMHL 401

Query: 231 IDL 233
            +L
Sbjct: 402 YEL 404


>UniRef50_B8GLW1 Phosphoadenosine phosphosulfate reductase n=1 Tax=Thioalkalivibrio
           sp. HL-EbGR7 RepID=B8GLW1_THISH
          Length = 378

 Score =  153 bits (386), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 55/316 (17%), Positives = 101/316 (31%), Gaps = 48/316 (15%)

Query: 11  QLEAESIHIIREVA-AEFSNPVMLYSIGKDSSVMLHLARKAFYPGT----LPFPLLHVDT 65
            L AE+   ++E   A+    ++ YS GKDS+++LHL              P  ++  DT
Sbjct: 13  DLVAETKTALKEAYLADGRPWIVAYSGGKDSTLVLHLVYDVLVELGKHAIKPVYVISSDT 72

Query: 66  GWKFREMYEFRDRT-------AKAYGCELLVHKNPEG---------VAMGINPFVHGSAK 109
             +   +  +           A+     L+                +  G  P       
Sbjct: 73  QVEAPNIVNYVRDVLTAVQKDAERRNLPLICEMVRPAVPETFWSKLIGRGYPPPTRWFRW 132

Query: 110 HTDIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRP 165
            T  MK +  ++A++    K+G      G+R  E   R K                  R 
Sbjct: 133 CTTTMKIKPSRRAIDKITAKHGSVILLLGSRTAESTIRKK--------------GMESRV 178

Query: 166 ELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           + + N N       +  + P++ WT+ ++W +++  N      Y   +   L R      
Sbjct: 179 KNFRNLNAHHEIPNAFVLAPIATWTDDEVWDFLYTHN-PPAWKYPHDQIISLYRQ----A 233

Query: 226 IDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE-RQGRV 284
           I      +           RF   GCW  T      +        +  +   ++ R    
Sbjct: 234 IGGECPVVMDLNTPSCGGGRF---GCWTCTVVKLDKSMEGFIQTGDAWMKPLADFRSWLK 290

Query: 285 IDRDQAGSMELKKRQG 300
             R+Q      ++R G
Sbjct: 291 EFREQPHVRMNRRRDG 306


>UniRef50_Q9YA63 Putative uncharacterized protein n=1 Tax=Aeropyrum pernix
           RepID=Q9YA63_AERPE
          Length = 464

 Score =  153 bits (386), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 55/242 (22%), Positives = 91/242 (37%), Gaps = 33/242 (13%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           + +   + LR LE  S  ++R V  +    ++ +S GKDS+  L LA +AF  G      
Sbjct: 212 LVEANRSILRVLEQHSAEVLRMVGEDVDTVIVPWSGGKDSTAALLLAVEAF--GRDAVKA 269

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKN--PEGVAMGINPFVHGSAKHTDIMKTEG 118
           ++VDTG  F E  E+ ++ A   G +L+  +    EG+ +   P      +     K E 
Sbjct: 270 VYVDTGIDFIENAEYVEKVASTLGVDLVYARADVDEGLLIEGMPMPDPEYRWCTGRKLEA 329

Query: 119 LKQALN--KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           L+QA      G      G R  E + R K     + ++                      
Sbjct: 330 LRQAFRTVSRGKTVVVTGDRDGESEKRGKRPPLRYDEKLG-------------------- 369

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
                 V PL  W+   +  YI  + I + PLY A       R G  +       +++  
Sbjct: 370 ---YPVVSPLKLWSGGHVQLYILSKGIPLNPLYEAG----FYRIGCYLCFALRSWEIEVM 422

Query: 237 EV 238
           + 
Sbjct: 423 KR 424


>UniRef50_B8ELQ2 Phosphoadenosine phosphosulfate reductase n=8
           Tax=Alphaproteobacteria RepID=B8ELQ2_METSB
          Length = 263

 Score =  153 bits (385), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 50/283 (17%), Positives = 85/283 (30%), Gaps = 86/283 (30%)

Query: 16  SIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
              ++R    +       ++ S G DS+V+LH+  +         P+L +DTG  F E  
Sbjct: 31  PQRLLRIAIEDLFPGKLALVSSFGADSAVLLHMIAEI----DRSLPVLFLDTGVLFPETL 86

Query: 74  EFRDRTAKAYGCELLVHKNPE-----GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
            +RD+  +  G   +V   P+             +     +  +I K   L +AL+  GF
Sbjct: 87  AYRDKLIERLGLTHVVTLVPDEATLESEDPETFLWSSHPDRCCEIRKVIPLARALD--GF 144

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
           DA   G +R +  +RA   ++   D                            ++ PL+N
Sbjct: 145 DAWISGRKRFQASTRAALPLFETED-------------------------NRTKINPLAN 179

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           W+   I  Y+   ++    L                                        
Sbjct: 180 WSPTQILNYLRAHDLPRHELVAKGYPS--------------------------------- 206

Query: 249 LGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           +GC P T  V                     R GR   R +  
Sbjct: 207 IGCIPCTSKVRP---------------GEDPRAGRWRGRAKVE 234


>UniRef50_P56860 Phosphoadenosine phosphosulfate reductase n=4 Tax=Bacteria
           RepID=CYSH_DEIRA
          Length = 255

 Score =  152 bits (384), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 56/283 (19%), Positives = 85/283 (30%), Gaps = 81/283 (28%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           E +   IIR   A   + +M  +   +  V+L LA +A Y G     ++ VDTG+ F E 
Sbjct: 40  ETDPRDIIRWALAAHPDLLMPSAFNLNGVVLLDLAAQAGYRG----EVVFVDTGYHFPET 95

Query: 73  YEFRDRTAKAYG-CELLVHKNPEGVAMGINPFV---HGSAKHTDIMKTEGLKQALNKYGF 128
              RDR    Y     +          G  P               K + L++ L + G 
Sbjct: 96  LATRDRLESRYPELTFVTLNAGASPDDGQTPPDLYASDPDACCAARKVDPLQRYLKEQGP 155

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
            A      RD+  +RA                                 G   RV PL++
Sbjct: 156 SALLNARSRDQASTRADIPFVE-------------------------EGGARRRVNPLAH 190

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           WT + +  Y    ++ + PLY                                    F +
Sbjct: 191 WTREQLEAYAAEHDLPVNPLYFDG---------------------------------FLS 217

Query: 249 LGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           +GCWP T AV+                    R GR   + +  
Sbjct: 218 IGCWPCTRAVKP---------------GEDARAGRWAGKGKTE 245


>UniRef50_P72794 Phosphoadenosine phosphosulfate reductase n=23 Tax=Bacteria
           RepID=CYSH_SYNY3
          Length = 249

 Score =  152 bits (384), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 50/256 (19%), Positives = 95/256 (37%), Gaps = 40/256 (15%)

Query: 1   MDQIRLTHLR-QLE-AESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLP 57
           + ++ L  L+ +LE A +  II   A  F    VM  S G  ++VMLHL           
Sbjct: 5   LTKLDLPTLQTELENATAQQIITWAAQTFGPGLVMSTSFGIQAAVMLHLVTSIV----PN 60

Query: 58  FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPF--------VHGSAK 109
            P++ +DTG+   E Y+F D+        L V+++P   A     +        V    +
Sbjct: 61  IPVIWIDTGYLPLETYQFADQLTGRLQLNLKVYQSPLSPARMEALYGKLWQQKDVESLNR 120

Query: 110 HTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWH 169
           +  I K E +++AL +    A   G RRD+ + R   +                      
Sbjct: 121 YDQIRKVEPMQRALKELEAIAWLTGLRRDQTRHRQNLKPVDL------------------ 162

Query: 170 NYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDN 229
                  +G   +V P+ +W  + +++Y+   ++   P +      V +      ++  +
Sbjct: 163 -------QGNQYKVLPILDWNSKMVYEYLTAHDLPYHPFFDQGYVSVGDWHSSRPLMAHD 215

Query: 230 RIDLQPGEVIKKRMVR 245
             +        K+   
Sbjct: 216 EDERDTRFHGLKQECG 231


>UniRef50_A2BKK3 Phosphoadenosine 5'-phosphosulfate reductase n=1 Tax=Hyperthermus
           butylicus DSM 5456 RepID=A2BKK3_HYPBU
          Length = 660

 Score =  152 bits (383), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 50/237 (21%), Positives = 74/237 (31%), Gaps = 35/237 (14%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
             L +LE E++  +        + ++  S GKDS+V   LA KA             DTG
Sbjct: 223 ERLERLEREAVEFLENRVKGLGDVMVAVSGGKDSTVAAALAVKAGLR-----RAYFFDTG 277

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEGLKQAL 123
            +F E  E   R A+  G ++            +    P          ++K   L +AL
Sbjct: 278 IEFPETIETAHRVAQTLGLDMAEISAGNTFWRALRLFGPPARDYRWCCKVVKFAPLAKAL 337

Query: 124 NKYGFD--AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
                       G R  E   RA     S      R D                      
Sbjct: 338 KPLVKTRLVTVTGQRGYESTQRAMAGKLSPSATTGRRDLL-------------------- 377

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
              P+  WT  D++ YIW E + + PLY        ER G  +       ++     
Sbjct: 378 -AAPIQEWTSLDVYAYIWREKLPLNPLYEMGY----ERVGCYLCPTSRLAEIDVARK 429


>UniRef50_Q164V6 Phosophoadenylyl-sulfate reductase n=24 Tax=Rhodobacterales
           RepID=Q164V6_ROSDO
          Length = 253

 Score =  151 bits (382), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 53/299 (17%), Positives = 93/299 (31%), Gaps = 89/299 (29%)

Query: 5   RLTHLRQLEAE---------SIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGT 55
           R   L+ L  E         ++ +++   AE +   ++ S G +S  +LHLA        
Sbjct: 15  RTDELQALVQELNTRLRHHGAVDVLQVALAEITPLSLVSSFGAESVALLHLASMV----D 70

Query: 56  LPFPLLHVDTGWKFREMYEFRDRTAKAYGC-ELLVHKNPE--GVAMGINPFVHGSAKHTD 112
              P++ VDT   F +   ++   A+  G   L + ++ +            H       
Sbjct: 71  RNIPVIFVDTEMLFTQTLVYQQELAERLGLRNLRIVRSGDIAHRDPTGTMHRHDPDGCCA 130

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           + KTE L++AL   G +    G +R +   RA    +    +  R               
Sbjct: 131 LRKTEPLQKAL--VGSNGWITGRKRYQSGQRAALEHFEIEAQTGR--------------- 173

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
                   I+V PL+ W   D+  YI    +   PL                        
Sbjct: 174 --------IKVNPLAYWQAGDVADYITENRLPRHPLVAQG-------------------- 205

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                        + ++GC P T  V+S                   R GR  + ++  
Sbjct: 206 -------------YPSIGCAPCTSPVQS---------------GEDARAGRWRNTEKDE 236


>UniRef50_Q01NE3 Adenylylsulfate kinase / phosphoadenylylsulfate reductase
           (Thioredoxin) n=5 Tax=cellular organisms
           RepID=Q01NE3_SOLUE
          Length = 426

 Score =  151 bits (381), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 48/298 (16%), Positives = 88/298 (29%), Gaps = 90/298 (30%)

Query: 6   LTHLRQLEAE-SIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
           + +L + EA  +  ++      F     +  S  K+   ++ LA +          +  +
Sbjct: 1   MDNLPEFEAATASEVLSWAIDTFGESFAIATSFQKEGMAIVDLASRISSE----IRVFTL 56

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---------NPFVHGSAKHTDIM 114
           DTG    E Y+  +   + YG ++ V          +            V G  +  ++ 
Sbjct: 57  DTGRLPDETYQMMEMVRRRYGIQVEVIFPDRAEVESLVTIHGPNLFYASVPGRERCCEVR 116

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K   L++ L      A   G RRD+  +R+                              
Sbjct: 117 KVRPLERKLQSLK--AWATGLRRDQSATRSAVPKV------------------------- 149

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                 +++ PL++WT   + +Y+   N+ + PLY                         
Sbjct: 150 ARVDGRLKLNPLADWTAAQVEEYLARHNVPLHPLYERGYT-------------------- 189

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGS 292
                        ++GC P T  VE                  SER GR    + A  
Sbjct: 190 -------------SIGCAPCTRPVEP---------------GESERAGRWWWEEDAKK 219


>UniRef50_Q2Y9X1 Phosphoadenylylsulfate reductase (Thioredoxin) n=9 Tax=Bacteria
           RepID=Q2Y9X1_NITMU
          Length = 256

 Score =  151 bits (380), Expect = 3e-35,   Method: Composition-based stats.
 Identities = 51/289 (17%), Positives = 82/289 (28%), Gaps = 86/289 (29%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L Q  AE   ++  V  ++       S G +  V+  L  + +        +  +DTG  
Sbjct: 7   LDQKIAEVRTLLERVQKDYLPATFANSFGAEDMVLTDLIARHY----PDIEMFTLDTGRL 62

Query: 69  FREMYEFRDRTAKAYGCELLVHKNPEGVAM------GINPFVHGSA---KHTDIMKTEGL 119
            +E Y+   +  + YG  + V+              G N F        K   I K E L
Sbjct: 63  PQETYDLMQQVTERYGIRIPVYFPDAAAVEAYVAQNGPNAFYDSVDLRKKCCHIRKVEPL 122

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           K+AL      A   G RRD+  +R       F                            
Sbjct: 123 KRALRD--KRAWITGLRRDQAPTRKGLVESEFDAENG----------------------- 157

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
             +  PL +W++ D+W Y+   ++    L+                              
Sbjct: 158 LQKFSPLLDWSQADVWAYLKQFDVPYNALHDKGYT------------------------- 192

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRD 288
                   ++GC P T A+                     R GR    D
Sbjct: 193 --------SIGCAPCTRAI---------------TPGEDVRAGRWWWED 218


>UniRef50_A6Q5M8 Phosphoadenosine phosphosulfate reductase n=1 Tax=Nitratiruptor sp.
           SB155-2 RepID=A6Q5M8_NITSB
          Length = 439

 Score =  151 bits (380), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 52/324 (16%), Positives = 96/324 (29%), Gaps = 55/324 (16%)

Query: 9   LRQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGT-------LPFPL 60
           L +        +RE     + P V+ +S GKDS+ +L L  +                 +
Sbjct: 2   LEEKVKAVKQKLREEFLIDNRPWVITFSGGKDSTAVLQLTIEMLLDLKEEGYKDLKKVYI 61

Query: 61  LHVDTGWKFREMYE-----------FRDRTAKAYGCELLVHKNPEG-------VAMGINP 102
           +  DT  +   + E           F D++      E+ V K           +  G   
Sbjct: 62  VSSDTKVEMPIIEEYLDNKLQAIQDFIDKSGLNLNIEIKVLKPKVSETFWTLLLGKGYPS 121

Query: 103 FVHGSAKHTDIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRW 158
                   TD +K +     L     K+       G R  E ++RA+             
Sbjct: 122 PNQNFRWCTDRLKIKPATYFLKNLAYKHKSIIMLLGVRSAESQNRAQ------------- 168

Query: 159 DPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE 218
               +R      ++   +   +    P+ +W+  D+W Y+                  + 
Sbjct: 169 -SIEKRVLNHRGFSKHDSIPNAFVFSPIRDWSNADVWTYLSKNQAPW------GSHKDMM 221

Query: 219 RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEE-MLVSTT 277
           +       + +       E       RF   GCW  T   +  +       EE + ++  
Sbjct: 222 KLYDKGSGEADCNIALNPEAPSCGKTRF---GCWVCTVVSKDKSMENMLRNEEDLWMAPL 278

Query: 278 SE-RQGRVIDRDQAGSMELKKRQG 300
            E R    I R      + ++R G
Sbjct: 279 HEFRNKLEIYRYDHSKRQNRRRNG 302


>UniRef50_A1SC70 Phosphoadenylylsulfate reductase (Thioredoxin) n=1 Tax=Nocardioides
           sp. JS614 RepID=A1SC70_NOCSJ
          Length = 229

 Score =  151 bits (380), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 56/292 (19%), Positives = 96/292 (32%), Gaps = 80/292 (27%)

Query: 1   MDQIRLTHLRQLEAESIH-IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           +  +   H  +LE  S   ++R     F   +   S   D + + HLA            
Sbjct: 11  LQAVVFEHAEELEGVSADSVVRWARDTFGTKLCATSSMSD-AAITHLASSCA----PGLD 65

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
           +L +DTG+ F E   FRD+ A A+   ++  ++       I P+   S     + K   L
Sbjct: 66  VLFLDTGYHFPETLAFRDQVAAAFDVRVVDLRSKPAPGNQIPPWSTDSNDCCRLRKVVPL 125

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           +QAL   G+DA   G RR E  SR++  + S+                        +  +
Sbjct: 126 RQALA--GYDAWLTGIRRAESPSRSQTPVVSWD-----------------------SHNQ 160

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
            ++V PL+ WT++ +  Y+    +    L                               
Sbjct: 161 VVKVAPLAAWTDEALAAYLHEHALPGNRLTELG--------------------------- 193

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                 + ++GC P T                 L   T  R GR   + +  
Sbjct: 194 ------YPSIGCEPCTS----------------LPVGTDARSGRWPGQHKTE 223


>UniRef50_C9RRS4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Fibrobacter
           succinogenes subsp. succinogenes S85 RepID=C9RRS4_FIBSS
          Length = 579

 Score =  151 bits (380), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 53/256 (20%), Positives = 87/256 (33%), Gaps = 36/256 (14%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
                 L  L +E+   I++ AA +   N V+ +S GKDSSV   +  KA   G      
Sbjct: 152 AANKNRLNALISEAHAFIKKEAANYPEENIVLSFSGGKDSSVTADIVTKAL--GNPSLVH 209

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEG-----VAMGINPFVHGSAKHTDIMK 115
           +  +T  +F +  E+  R  K +   +      E      V   I P          + K
Sbjct: 210 IFGNTTLEFPQTVEYAKRFKKNHPFAIFETSINEDQNFMDVCEDIGPPARIMRWCCSMFK 269

Query: 116 TEGLKQALN---KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           T  + + LN   +      F G RR E  SR+K                           
Sbjct: 270 TGPITRVLNSLYRNQQILTFYGIRRAESASRSKYNRVESGKE------------------ 311

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI-DDNRI 231
             +   +     P+ +W + DIW Y+  EN+D    Y        +R G      ++ R 
Sbjct: 312 -SVKIQKQTVASPIIDWKDIDIWLYLLAENVDFNDAYRLGY----DRVGCWCCPNNNQRA 366

Query: 232 DLQPGEVIKKRMVRFR 247
                  + +   ++R
Sbjct: 367 QFLSRIYMPENSKKWR 382


>UniRef50_B9XLS6 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=1 Tax=bacterium
           Ellin514 RepID=B9XLS6_9BACT
          Length = 260

 Score =  150 bits (379), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 46/275 (16%), Positives = 79/275 (28%), Gaps = 78/275 (28%)

Query: 16  SIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           +  ++     +F     +  S      VM+HLA++      + FP+  +DTG  F E   
Sbjct: 36  TEEVLTWAWEKFGKRAAIGTSFQGAGLVMMHLAKQ----SGIQFPVFTLDTGLLFPETLA 91

Query: 75  FRDRTAKAYGCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
            + R    +G  +           +  A G   +         + K   L+  L     D
Sbjct: 92  LKKRLEDFFGFGIESLVPDLTLEQQAEAQGPELWKREPDLCCTMRKVLPLRSKLADL--D 149

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
               G RR +  +R+   I                              + +++ P++NW
Sbjct: 150 CWITGLRRQQSDTRSSIGIIELYAFDETAGR------------------DIVKLNPMANW 191

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
           + + +W YI    I   PL                                      R++
Sbjct: 192 SREAVWNYIKEHKIPYNPLQDQGY---------------------------------RSI 218

Query: 250 GCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRV 284
           GC P T    S                 +ER GR 
Sbjct: 219 GCQPCTNKTAS---------------GENERAGRW 238


>UniRef50_P92979 5'-adenylylsulfate reductase 1, chloroplastic n=74 Tax=cellular
           organisms RepID=APR1_ARATH
          Length = 465

 Score =  149 bits (377), Expect = 9e-35,   Method: Composition-based stats.
 Identities = 52/290 (17%), Positives = 97/290 (33%), Gaps = 80/290 (27%)

Query: 9   LRQLEAES-IHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            ++LE  S + I+ +   ++ N   + +S G +   ++    +  +    PF +  +DTG
Sbjct: 97  AKKLENASPLEIMDKALEKYGNDIAIAFS-GAEDVALI----EYAHLTGRPFRVFSLDTG 151

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV---HGSAKHTDIMKTEGL 119
               E Y F D   K YG  +          +G+      F     G  +   + K   L
Sbjct: 152 RLNPETYRFFDAVEKHYGIRIEYMFPDSVEVQGLVRSKGLFSFYEDGHQECCRVRKVRPL 211

Query: 120 KQALNKYGFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           ++AL   G  A   G R+D+   +R++  +      F   D                  G
Sbjct: 212 RRALK--GLKAWITGQRKDQSPGTRSEIPVVQVDPVFEGLDG---------------GVG 254

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             ++  P++N    D+W ++   ++ +  L+ A                           
Sbjct: 255 SLVKWNPVANVEGNDVWNFLRTMDVPVNTLHAAG-------------------------- 288

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRD 288
                  + ++GC P T AV               +    ER+GR    D
Sbjct: 289 -------YISIGCEPCTKAV---------------LPGQHEREGRWWWED 316


>UniRef50_D0N1L8 Phosphoadenosine phosphosulfate reductase n=2 Tax=cellular
           organisms RepID=D0N1L8_PHYIN
          Length = 382

 Score =  149 bits (376), Expect = 9e-35,   Method: Composition-based stats.
 Identities = 45/234 (19%), Positives = 91/234 (38%), Gaps = 38/234 (16%)

Query: 13  EAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
           E  +  I++     F    V+  S G  S+VMLHL R      +   P++ VDTG+  +E
Sbjct: 54  EKTAQEIVQWTFDTFGARTVLSSSFGIQSAVMLHLTRSV----SKDIPVVWVDTGYLPKE 109

Query: 72  MYEFRDRTAKAYGCELLVHKNPEGVAMGINPF--------VHGSAKHTDIMKTEGLKQAL 123
            Y+F     K     + V+++P   A     +             ++  + K E +++AL
Sbjct: 110 TYQFAAHLTKLLDLNVRVYQSPITPARMEALYGKLYEIETPEAHRQYGYMRKVEPMQRAL 169

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           ++    A   G R D+ + R   +  +  +                           +++
Sbjct: 170 DELNAAALLVGVRADQTQHRQHMKHVNVYE-------------------------GRLKI 204

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
            P+ NW++Q+I QY+    ++  PL       V +      + + ++ + + G 
Sbjct: 205 CPILNWSKQEIEQYMTANQLEYHPLKAQGYESVGDAHSSRPVTEADKGNDRAGR 258


>UniRef50_A4XB35 Phosphoadenylylsulfate reductase (Thioredoxin) n=3
           Tax=Actinomycetales RepID=A4XB35_SALTO
          Length = 256

 Score =  149 bits (376), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 54/288 (18%), Positives = 96/288 (33%), Gaps = 84/288 (29%)

Query: 10  RQLE-AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           R+LE A ++ ++R     F +   + S   D +V++HL  +          ++ +DTG  
Sbjct: 42  RELEGAPALEVVRWAVERFGDRFCVTSSMAD-AVLVHLVSRVA----PGVDVVFLDTGLH 96

Query: 69  FREMYEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           F E    RD+ ++     +   +       +    G   F         + K E L++AL
Sbjct: 97  FPETLRVRDQVSRTMPVNVRSIRPRLTVGQQDGEYGPRLFHRSPDDCCQLRKVESLERAL 156

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G+DA   G RRD+  SRA   + +F  R  +                        +V
Sbjct: 157 --VGYDAWATGLRRDDSPSRANTPVVTFDTRRGKV-----------------------KV 191

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            P++ WT+ D+  YI   ++ +  L                                   
Sbjct: 192 NPIAAWTQADVETYISQWDVPVNEL---------------------------------FG 218

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
             + ++GCWP T                   +    R GR    ++A 
Sbjct: 219 RAYSSVGCWPCTRRTR---------------AGEDARAGRWAMFEKAE 251


>UniRef50_B6ASY4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Rhodobacterales
           bacterium HTCC2083 RepID=B6ASY4_9RHOB
          Length = 243

 Score =  149 bits (375), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 60/287 (20%), Positives = 96/287 (33%), Gaps = 82/287 (28%)

Query: 10  RQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
           R LEA S   + +   +     ++   G DS+V+LHLA +         P+L +DTG  F
Sbjct: 15  RALEATSAIRLGQSDPQVGQIALVSGFGADSAVLLHLAAQLV----PDMPVLFLDTGKHF 70

Query: 70  REMYEFRDRTAKAYGC-ELLVHKNPEGVAMGINPF----VHGSAKHTDIMKTEGLKQALN 124
            E  +++   A   G  +L   K         +P+     H      D+ KT+ L  AL 
Sbjct: 71  NETLQYQRELASELGLQDLRTIKPDANAIAETDPYGALYSHAPDACCDLRKTQPLTLALK 130

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             GFD    G +R +  SRAK  ++    +                          +++ 
Sbjct: 131 --GFDGWITGRKRHQSVSRAKMNVFEIDGQSQ-----------------------QLKIN 165

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL++W+ QD+ QY+    +   PL                                    
Sbjct: 166 PLAHWSAQDVAQYMRDHALLPHPLVARG-------------------------------- 193

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
            F ++GC P T A                +S    R GR     +  
Sbjct: 194 -FLSIGCSPCTSAT---------------LSGEDPRTGRWRGTAKDE 224


>UniRef50_Q3YAU0 5'-adenylylsulfate reductase n=2 Tax=Viridiplantae
           RepID=Q3YAU0_9ASPA
          Length = 423

 Score =  149 bits (375), Expect = 1e-34,   Method: Composition-based stats.
 Identities = 48/284 (16%), Positives = 86/284 (30%), Gaps = 79/284 (27%)

Query: 14  AESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A  + I+    AEF N   + +S G +   ++    +       PF +  +DTG    E 
Sbjct: 53  ASPLEIMDRALAEFGNDIAIAFS-GAEDVALI----EYARLTGRPFRVFSLDTGRLNPET 107

Query: 73  YEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV---HGSAKHTDIMKTEGLKQALNK 125
           Y + +   K Y   +          + +      F     G  +   + K   L++AL  
Sbjct: 108 YRYFNEVEKHYNIHIEYMFPDAVEVQALVRNKGLFSFYEDGHQECCRVRKVRPLRRALK- 166

Query: 126 YGFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            G  A   G R+D+   +RA   +      F                      G  I+  
Sbjct: 167 -GLRAWVTGQRKDQSPGTRAHIPVVQVDPTFE---------------GSDGGAGSLIKWN 210

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P++N   +D+W ++    + +  L+                                   
Sbjct: 211 PVANVDGKDVWNFLRTMEVPVNSLHAKG-------------------------------- 238

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRD 288
            + ++GC P T  V               +    ER+GR    D
Sbjct: 239 -YVSIGCEPCTRPV---------------LPGQHEREGRWWWED 266


>UniRef50_A7MSZ6 Phosphoadenosine phosphosulfate reductase n=283 Tax=Bacteria
           RepID=CYSH_VIBHB
          Length = 259

 Score =  148 bits (372), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 48/228 (21%), Positives = 85/228 (37%), Gaps = 40/228 (17%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           + QI +  L QL   +   ++           +  S G  ++VMLHL  +         P
Sbjct: 26  LAQINVE-LEQL--SAQERVKWALENLEGEFAVSSSFGIQAAVMLHLVTQ----QKPDIP 78

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPF-------VHGSAKHTD 112
           ++  DTG+ F E Y+F D+        L V++  E        +       + G  K+  
Sbjct: 79  IILTDTGYLFAETYQFIDQLKAQLNLNLKVYRAKESANWQEARYGKLWEQGIEGIEKYNK 138

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           I K E +++AL +      F G RR++ +SRA   I S ++                   
Sbjct: 139 INKVEPMRRALREQNVGTWFSGLRREQSQSRAGLPILSIQN------------------- 179

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
                    +  P+ +WT +D+  Y+    +   PL+      V +  
Sbjct: 180 ------GVFKFLPVIDWTNKDVHYYLEEHGLSYHPLWEQGYLSVGDTH 221


>UniRef50_Q1AXE9 Phosphoadenylylsulfate reductase (Thioredoxin) n=1 Tax=Rubrobacter
           xylanophilus DSM 9941 RepID=Q1AXE9_RUBXD
          Length = 251

 Score =  147 bits (371), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 49/289 (16%), Positives = 89/289 (30%), Gaps = 85/289 (29%)

Query: 11  QLE-AESIHIIREVAAEFSN-PVMLYS-IGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +LE A    ++R     F     +  S  G +  V+L +  +          +  +DTG+
Sbjct: 25  ELEGAAPQEVLRWAVGFFGRRLTLSVSFGGPEGMVLLDMLSRITD----DVWVFTLDTGF 80

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVA-----MGINPFVHGSAKHTDIMKTEGLKQA 122
            F E   FR+   + Y   L V +    V       G   +        ++ K E  ++ 
Sbjct: 81  LFEETVRFREEAMRRYRLPLRVVRPELSVEEQVERYGPRLWSCAPDICCEVRKVEPQRRW 140

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           L+   FDA   G RRD+  +RA   +  + + F                          +
Sbjct: 141 LS--NFDAWVTGIRRDQTAARADTPVVGWDEFFG-----------------------VFK 175

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           + PL++W+ + + +Y     + + PL                                  
Sbjct: 176 IAPLASWSRERVLRYAGEHGVPLNPLLSRG------------------------------ 205

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
              + ++GC P T  V                    ER GR    ++  
Sbjct: 206 ---YASIGCEPCTRPVR---------------EGEDERAGRWPGMEKTE 236


>UniRef50_B7R5I5 Iron-sulfur protein n=1 Tax=Thermococcus sp. AM4 RepID=B7R5I5_9EURY
          Length = 377

 Score =  147 bits (371), Expect = 5e-34,   Method: Composition-based stats.
 Identities = 42/223 (18%), Positives = 77/223 (34%), Gaps = 36/223 (16%)

Query: 24  AAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAK 81
             +F      + +S GKDS V LHLA +           +  DT  +  +  E+      
Sbjct: 18  LRQFPKSAIAVSFSGGKDSLVALHLASRVGIR-----RAVFSDTTIESSKTIEYIKEVET 72

Query: 82  AYGCELLVHKNPEGVAM---GINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRD 138
             G ++ + +  +        + P           +K   L +   K+       G RR+
Sbjct: 73  ILGVKIDIVRPQKSFWELLPMLGPPSTRHRWCCPTIKYPQLSEYAKKHHIKYYITGLRRN 132

Query: 139 EEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYI 198
           E   R +                      +            I+V P+ +WTE ++W+YI
Sbjct: 133 ESLIRME----------------------YKKIGKNPMIPYVIQVNPIIDWTENEVWEYI 170

Query: 199 WLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
              N+ I P Y       L R+G ++    +  +L+  + I+ 
Sbjct: 171 KKYNLPIHPNYKLG----LSRNGCVICPYKSPKELRKLKEIEP 209


>UniRef50_Q11B66 Phosphoadenosine phosphosulfate reductase n=36
           Tax=Alphaproteobacteria RepID=CYSH_MESSB
          Length = 245

 Score =  147 bits (370), Expect = 6e-34,   Method: Composition-based stats.
 Identities = 57/285 (20%), Positives = 91/285 (31%), Gaps = 87/285 (30%)

Query: 15  ESIHIIREVAAEF---SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
            +  I+      F        + S G DS+V+LH+            P+L +DTG  F E
Sbjct: 25  AAEAIVELAVNRFRDEGGIATVSSFGADSAVLLHMVASV----DKSLPVLFLDTGQHFGE 80

Query: 72  MYEFRDRTAKAYGCELLVHKNPEGV-----AMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
             E+RD+ A   G   LV  +P+         G +     S    +I K E + +A+  Y
Sbjct: 81  TIEYRDQLASDLGLSNLVVVHPKSEMLSARDPGNDLHKSDSDLCCEIRKVEPMARAVEPY 140

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
              A F G +R + +SRA+  ++                            G  IR+ PL
Sbjct: 141 --SAWFTGRKRHQAESRAQMPVFE-------------------------AVGPRIRINPL 173

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
           + WT  D   Y+   ++   PL                                      
Sbjct: 174 ARWTTADQAAYMRANDLRENPLVAYGYL-------------------------------- 201

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
            ++GC+P T  V+                   +R GR     +  
Sbjct: 202 -SIGCFPCTQPVKP---------------GEDQRSGRWAGLAKTE 230


>UniRef50_C5SCG2 Adenylylsulfate reductase, thioredoxin dependent n=3
           Tax=Proteobacteria RepID=C5SCG2_CHRVI
          Length = 256

 Score =  146 bits (368), Expect = 9e-34,   Method: Composition-based stats.
 Identities = 49/293 (16%), Positives = 88/293 (30%), Gaps = 86/293 (29%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
             +    L   EA +I ++ +V  E  + V   S+G +  V+     +      LP  + 
Sbjct: 7   PSLSTDTLPTREAAAIELLSQVCRELDSIVFATSLGAEDMVLT----EIIRRERLPIRIF 62

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV------AMGINPFVHG---SAKHTD 112
            +DTG    E  E  +   + YG  +  +              G++ F            
Sbjct: 63  TLDTGRLPTETLELIEVVERHYGTRIERYAPHPDAIADYVSRYGLDGFYDSVPARQACCR 122

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           + K E LK+AL   G  A   G R ++  +RA+     +                     
Sbjct: 123 VRKLEPLKRALA--GQSAWVTGLRAEQSVTRAELPAREWDAANG---------------- 164

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
                    ++ PL++W+E ++W +I    +   PL+                       
Sbjct: 165 -------LEKINPLADWSEHEVWAFIRHHRVPYNPLHNQG-------------------- 197

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                        + ++GC P T A+                     R GR  
Sbjct: 198 -------------YPSIGCAPCTRAI---------------TVGEDVRAGRWW 222


>UniRef50_B5Y5U1 Predicted protein (Fragment) n=1 Tax=Phaeodactylum tricornutum CCAP
           1055/1 RepID=B5Y5U1_PHATR
          Length = 272

 Score =  146 bits (368), Expect = 9e-34,   Method: Composition-based stats.
 Identities = 38/237 (16%), Positives = 81/237 (34%), Gaps = 31/237 (13%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           + + +   L+ LE +++  ++     + N V   ++     V+ HL  +  Y       +
Sbjct: 53  IAESKEMRLKHLEEQAMFALKIAVENYGNAVFPNAMIAGDVVITHLLSRLGYLENGKAKI 112

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE---------GVAMGINPFVHGSAKHT 111
           + VDT   F E  EF ++  + Y  +  V    +             G N +     ++ 
Sbjct: 113 MVVDTFHLFPETMEFLEKLEEHYNFKADVFCADKIPVGDKDAFDKRYGANLWKEDIDEYD 172

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            + K E  ++ L     D    G  R +   RA   ++                      
Sbjct: 173 RVCKVEPFQRGLKTLKTDCMINGRTRWQGFERAWIDLFE--------------------- 211

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
                 G   +  P++ WT +D + YI   ++   PL+      + +    + + +D
Sbjct: 212 -NAPIGGGLAKCNPIAYWTLEDTFDYIAKYDVPYHPLHEKGYPSIGDAKDTIPVPED 267


>UniRef50_Q7NK24 Phosphoadenosine phosphosulfate reductase n=6 Tax=Bacteria
           RepID=CYSH_GLOVI
          Length = 241

 Score =  146 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 58/302 (19%), Positives = 94/302 (31%), Gaps = 88/302 (29%)

Query: 1   MDQIRLTHL-RQLEAESIH-IIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLP 57
           +DQ  L HL RQ E  +   I+ E    F    V+  + G +S ++L +  K +      
Sbjct: 12  IDQTTLEHLARQWEDLAPEAILAEAVRCFGDKLVLASAFGPESIILLDMLVKVW----PR 67

Query: 58  FPLLHVDTGWKFREMYEFRDRT-AKAYGCELLVH-----KNPEGVAMGINPFVHGSAKHT 111
                ++TG+ F E    +DR  A+    +L V         +    G            
Sbjct: 68  PQAFFLETGFHFPETLALKDRVLARFPQLQLEVVGPLMSVAQQNAIYGERLHDRNPDHCC 127

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            I K E L +AL  Y   A   G RR++  +R +  +  +  R                 
Sbjct: 128 AIRKVEPLNRALAPYK--AWIAGMRREQSPTRGQIGVVQWDSRRG--------------- 170

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                    ++  PL+ WT + +W YI   ++   PL+                      
Sbjct: 171 --------MVKFNPLATWTHKQVWAYIVERDLPYNPLHDEG------------------- 203

Query: 232 DLQPGEVIKKRMVRFRTLGCWP--LTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQ 289
                         F ++GC P   T  V   A                 R GR   + +
Sbjct: 204 --------------FPSIGCSPLNCTAPVADGADP---------------RSGRWRGKAK 234

Query: 290 AG 291
             
Sbjct: 235 TE 236


>UniRef50_Q3ICV8 Putative enzyme protein n=4 Tax=Gammaproteobacteria
           RepID=Q3ICV8_PSEHT
          Length = 555

 Score =  145 bits (366), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 52/329 (15%), Positives = 94/329 (28%), Gaps = 49/329 (14%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPG------ 54
                  L+    +SI  I+ +    S   V+ YS GKDS+ +L L   A          
Sbjct: 11  SAFNQDGLKNTIEQSIKHIKMLYQSDSIPWVIGYSGGKDSTAILQLIWYALQELAQEGKC 70

Query: 55  TLPFPLLHVDTGWKFREM-------YEFRDRTAKAYGCELLVHKNPEG---------VAM 98
                ++  DT  +   +        E     A A G  ++ H+             +  
Sbjct: 71  EKKVHVISTDTLVENPIVAMWVGKSLERMKEQADAQGLPIVPHRLTPAVKDRFWVNLIGK 130

Query: 99  GINPFVHGSAKHTDIMKTEG----LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDR 154
           G     +     TD +K       ++   +K G      G R+ E  +RA          
Sbjct: 131 GYPAPRYKFRWCTDRLKISPSNTFIQNMADKNGEAILVLGTRKAESTARA--------AS 182

Query: 155 FHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIV-PLYLAAE 213
             R++                +        P+++W+  D+W Y+   +     P +    
Sbjct: 183 MERFESSTTNTRKALGLTENGSLERVWVYTPIASWSNDDVWVYLNSVDNPWNFPNHDLMG 242

Query: 214 RPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEML 273
                 +G           +           RF   GC+  T   E  +       ++  
Sbjct: 243 MYQGATEG------GECPLVVDKSTQSCGDSRF---GCYVCTMVSEDKSMNAMIANDDEK 293

Query: 274 VSTTSERQGRVI----DRDQAGSMELKKR 298
                    R      D ++A  +E   R
Sbjct: 294 EWMYPLVALRNEIEVNDSNRAKKIEKLTR 322


>UniRef50_Q2FU39 Uncharacterized domain 2 n=2 Tax=Methanomicrobiales
           RepID=Q2FU39_METHJ
          Length = 466

 Score =  145 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 52/242 (21%), Positives = 83/242 (34%), Gaps = 39/242 (16%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           Q     L+++EA S   I +    +      + YS GKDS   L +    +       P+
Sbjct: 212 QANADVLKKVEAASGKFIADSIGPYEHLPMSVSYSGGKDSLATLLVVMNTYRK----MPI 267

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTE 117
           L++DTG +F    E        YG E +  ++            P    +       K E
Sbjct: 268 LYIDTGLEFPSTEENVCDVQDRYGLECVRIESINEFWRDFEVSGPPSRDNRWCCRTSKLE 327

Query: 118 GLKQAL----NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
            L+Q +     + G   +F G R+ E  SR K                   P +W N   
Sbjct: 328 PLRQYIVKTYGEDGEIVSFIGQRKYESFSRMK------------------NPRVWRNSYV 369

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
                  I + P+  WT   +W YI+ E      +Y       ++R G  M    +   L
Sbjct: 370 N----NQICLAPIHTWTALHVWLYIFREKAPFNEMYRHG----VDRMGCYMCPASDLGVL 421

Query: 234 QP 235
           + 
Sbjct: 422 EK 423


>UniRef50_A7HWV2 Phosphoadenosine phosphosulfate reductase n=1 Tax=Parvibaculum
           lavamentivorans DS-1 RepID=A7HWV2_PARL1
          Length = 252

 Score =  145 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 50/269 (18%), Positives = 85/269 (31%), Gaps = 72/269 (26%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCEL 87
               ++ S G +S+V+LH+  +         P++ ++TG  F E   FRDR  +  G   
Sbjct: 37  GKIAVVSSFGAESAVLLHMVAQV----DPTTPVIFLNTGKLFGETLRFRDRLQEKLGLTD 92

Query: 88  LVHKNPE-----GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKS 142
           +    P              +         + K   L++AL   GFDA+  G +R +  +
Sbjct: 93  IRAVGPHPADLAAKDPNGGLWNADPDACCYVRKVLPLERALA--GFDASITGRKRFQTNA 150

Query: 143 RAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN 202
           RA               P +             + G   ++ PLS W + D+ +Y+    
Sbjct: 151 RAGMDPIEEEKIRGTGVPGS-------------DAGTRFKINPLSYWGQDDLERYMDEYK 197

Query: 203 IDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNA 262
           +   PL                                     + ++GC P T  V    
Sbjct: 198 LPRHPLV---------------------------------KDNYLSIGCMPCTERVP--- 221

Query: 263 QTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                          S R GR + RD+  
Sbjct: 222 ------------EGGSYRDGRWVGRDKDE 238


>UniRef50_Q8DK35 Phosphoadenosine phosphosulfate reductase n=9 Tax=Cyanobacteria
           RepID=Q8DK35_THEEB
          Length = 246

 Score =  145 bits (365), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 47/267 (17%), Positives = 82/267 (30%), Gaps = 48/267 (17%)

Query: 1   MDQIRLTHLRQLE-----AESIHIIREVAAEFSNPVMLYS-IGKDSSVMLHLARKAFYPG 54
           M       L  L      A    I+     E    ++  S    D  V+  L  +   P 
Sbjct: 11  MAASVSFDLDALNQRFEGAHPRDILAWAVTEIPQGLVQTSAFNVDDMVITDLLYRDLRP- 69

Query: 55  TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPE-------GVAMGINPFVHGS 107
             P P+L +DT   F E   F  +  + Y  +L  +K P+           G   +    
Sbjct: 70  NPPVPVLFLDTLHHFAETLAFVQQAKEKYSLDLRTYKIPDVDSREAFAARYGDKLWETNV 129

Query: 108 AKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPEL 167
            +   + K E L++ L +    A   G RRD+  +RA                       
Sbjct: 130 EQFHHLTKIEPLQRGLAELHTVAWITGRRRDQALTRANMPYVELDKE------------- 176

Query: 168 WHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
                        +++ PL+ WT +  W Y+    +   PL+      + +      + +
Sbjct: 177 -----------GRLKINPLAAWTRKQTWAYVMEHGVIYNPLHDRGYASIGDEPLTTPIAE 225

Query: 228 DNRIDLQPGEVIKKRMVRFRTLGCWPL 254
                        +R  R+R +G    
Sbjct: 226 GE----------DERAGRWRGMGKTEC 242


>UniRef50_C0GLN5 Phosphoadenosine phosphosulfate reductase n=1
           Tax=Desulfonatronospira thiodismutans ASO3-1
           RepID=C0GLN5_9DELT
          Length = 186

 Score =  144 bits (364), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 60/262 (22%), Positives = 92/262 (35%), Gaps = 78/262 (29%)

Query: 43  MLHLARKAFYPGTL--PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI 100
           MLH                 L++DTG+KF E+ EFRD  A  +G EL V          +
Sbjct: 1   MLHQWMIFLQERGPGVQVRALNLDTGYKFPEVLEFRDEMAWEWGLELTVAGPDSSAMQDL 60

Query: 101 NPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP 160
                   +    +K   L++A+ ++G      G RRDE  SR                 
Sbjct: 61  QELSK--VECCRRLKVSPLQEAVREHGVRVLLTGIRRDEHPSRENTPDVQ---------- 108

Query: 161 KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
                        + N  +  +V P+++WTE DIW YI L+ +    LY A         
Sbjct: 109 -------------EKNDLDYYQVNPIAHWTEMDIWSYIMLKGLPYCSLYDAG-------- 147

Query: 221 GMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSER 280
                                    +R+LGC P T                   +  +ER
Sbjct: 148 -------------------------YRSLGCKPCTV----------------KGTHMNER 166

Query: 281 QGRVIDRDQAGSMELKKRQGYF 302
            GR  DR++  ++++ +  GYF
Sbjct: 167 SGR--DREKEENLDMLRSMGYF 186


>UniRef50_C9KJN4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Mitsuokella
           multacida DSM 20544 RepID=C9KJN4_9FIRM
          Length = 510

 Score =  144 bits (363), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 51/258 (19%), Positives = 90/258 (34%), Gaps = 36/258 (13%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
            +   HL+ +  E+   IRE A+++   N V+ +S GKDS+V   +  KA          
Sbjct: 86  TVNRHHLQSIIDEAHQFIREEASKYPAENIVLSFSGGKDSTVTADIVTKAL--SNPSLVH 143

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELL-----VHKNPEGVAMGINPFVHGSAKHTDIMK 115
           +  +T  +F     + +R  K +   +        +N   +   I P          + K
Sbjct: 144 IFGNTTLEFPTTLTYAERFRKNHPQAIFQIAQNREQNFMDMCKVIGPPARMMRWCCSMFK 203

Query: 116 TEGLKQALNKYGFD---AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           T  + + ++    +     F G RR E  SR+K                           
Sbjct: 204 TGPITRVISNLYRNQQILTFYGIRRYESVSRSKYNRVEKNTE------------------ 245

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDN-RI 231
             +   +     P+ NW + D+W YI  E ID    Y        +R G     ++N R 
Sbjct: 246 -SVKIQQQTVAAPIFNWKDIDVWLYILGEKIDFNDAYRLGY----DRVGCWCCPNNNKRA 300

Query: 232 DLQPGEVIKKRMVRFRTL 249
                  + +R  ++R  
Sbjct: 301 QFLSNIYMPERSTKWRNF 318


>UniRef50_A5W608 Phosphoadenylylsulfate reductase (Thioredoxin) n=12 Tax=Bacteria
           RepID=A5W608_PSEP1
          Length = 244

 Score =  144 bits (363), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 45/286 (15%), Positives = 82/286 (28%), Gaps = 82/286 (28%)

Query: 14  AESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
                I++     F  +  + +S G +  V++ +A K          +  +DTG    E 
Sbjct: 17  KSPQDILKLAFEHFGDDLWISFS-GAEDVVLVDMAWKL----NKQVKVFSLDTGRLHPET 71

Query: 73  YEFRDRTAKAYGCELLVHKNPEG----VAMGINPFV---HGSAKHTDIMKTEGLKQALNK 125
           Y F D+  + Y   + +                 F     G  +   I K E L++ L  
Sbjct: 72  YRFIDQVREQYNLPIEILSPDRAKLDPFVKEKGLFSFYKDGHGECCGIRKIEPLRRKLAT 131

Query: 126 YGFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
               A   G RRD+   +R++         F                     +    +  
Sbjct: 132 --VSAWATGQRRDQSPGTRSQVAALEIDSAF------------------STPERTLYKFN 171

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL+  + +++W YI +  +    L+                                   
Sbjct: 172 PLAQMSSEEVWGYIRMLELPYNSLHERG-------------------------------- 199

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQA 290
            F ++GC P T  V               +    ER+GR    +  
Sbjct: 200 -FISIGCEPCTRPV---------------LPNQHEREGRWWWEEST 229


>UniRef50_B8GIL3 Aminotransferase class V n=2 Tax=Archaea RepID=B8GIL3_METPE
          Length = 896

 Score =  144 bits (363), Expect = 3e-33,   Method: Composition-based stats.
 Identities = 43/244 (17%), Positives = 73/244 (29%), Gaps = 37/244 (15%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
              HL+ LE  ++  I++   +     + +S GKDS+     A  A            ++
Sbjct: 200 NRLHLKNLERFAVRTIKQHMHDRPTINVSFSGGKDST-----AALALARRAGVTDAFFIN 254

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPE-GVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           TG +F E  +F        G E++              P    +      +K   LK+ L
Sbjct: 255 TGLEFPETVDFVREQ----GVEVIDSGGDFWASVSKAGPPGKDNRWCCKSLKLHPLKRFL 310

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
            K G      G R  E  +RA                           +   N    + +
Sbjct: 311 AKTGPCVTVQGNRWYESWNRAGL----------------------EETSQNPNNPLQLNI 348

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID-DNRIDLQPGEVIKKR 242
            P+ NW   +++ Y+W   +    LY        ER G  +                   
Sbjct: 349 SPIRNWRAIEVFFYLWWRKVPFNSLYEEG----FERLGCYLCPAMLEAEGELIKRTHPDY 404

Query: 243 MVRF 246
             R+
Sbjct: 405 EARW 408


>UniRef50_Q1UZN4 Putative uncharacterized protein n=1 Tax=Candidatus Pelagibacter
           ubique HTCC1002 RepID=Q1UZN4_PELUB
          Length = 494

 Score =  144 bits (362), Expect = 5e-33,   Method: Composition-based stats.
 Identities = 51/331 (15%), Positives = 93/331 (28%), Gaps = 52/331 (15%)

Query: 1   MDQIRLTHLRQL-----EAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPG 54
           M+  + +   ++       + + +I ++  E  NP V+ YS GKDSS  L L  +     
Sbjct: 1   MENKKKSFFDEVGFKPTITKLVDLIAKLYLEDENPWVVGYSGGKDSSACLQLMWRVLEKI 60

Query: 55  T------LPFPLLHVDTGWKFREM-------YEFRDRTAKAYGCELLVHKNPEGVA---- 97
                   P  ++  DT  +   +        +     AK  G  +        +     
Sbjct: 61  KSENKVIKPLYVITTDTLVENPIVATWVKSSLDLLRDKAKDNGLPIFPSLLTPNIEETFW 120

Query: 98  -----MGINPFVHGSAKHTDIMKTEGLKQALNKY----GFDAAFGGARRDEEKSRAKERI 148
                 G           T+ MK     + L K     G      G R+ E  +RA+   
Sbjct: 121 VNLIGKGYPAPNTKFRWCTERMKIRPSDRFLRKLSNESGEAVIVLGTRKAESSNRAQS-- 178

Query: 149 YSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPL 208
                       + ++     N+   +N        P+ +WT  D+W Y+  +       
Sbjct: 179 ----------ISRFEKEATRQNFQPHVNLSNVSSFLPIKDWTNDDVWLYLLQDQSP---- 224

Query: 209 YLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEI 268
                   L               +           RF   GCW  T   +  + +    
Sbjct: 225 -WGINNKDLLTMYQGATDGGECPLVVDTSTPSCGDSRF---GCWVCTLVKQDKSMSAMVQ 280

Query: 269 IEEMLVSTTSERQGRVIDRDQAGSMELKKRQ 299
            +          Q R    ++       +R 
Sbjct: 281 NDSEKSWMEPLLQLRNDLTEKDFEKRDFRRL 311


>UniRef50_B3T667 Putative phosphoadenosine phosphosulfate reductase family protein
           n=1 Tax=uncultured marine crenarchaeote HF4000_ANIW141O9
           RepID=B3T667_9ARCH
          Length = 263

 Score =  143 bits (361), Expect = 6e-33,   Method: Composition-based stats.
 Identities = 42/308 (13%), Positives = 83/308 (26%), Gaps = 91/308 (29%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAE-FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
              +++ L         +++           +  S G +   ++H+  K          +
Sbjct: 29  TTEQVSELNDKLKTPEEVLQWGLENIHPKLALASSFGAEDVCVIHMLSKI----NPEARV 84

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA------MGINPFVH---GSAKHT 111
             +DTG   +E Y+  D   K Y  ++ +               G+N F           
Sbjct: 85  FSLDTGRLNQETYDVMDEIRKKYNSKIEITFPDASEVIEMVQTHGLNLFYESAENRKLCC 144

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            + K   L + L+    D    G R D+ ++R   +     ++                 
Sbjct: 145 GVRKVHPLNKMLSTL--DGWITGLRSDQTQNRQASKKIEIDEQHDS-------------- 188

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                    +++ P+ +W+      YI   +I    L                       
Sbjct: 189 --------MVKLNPILDWSWDQTMGYIKENDIPYNKLIDQG------------------- 221

Query: 232 DLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI-----D 286
                         F ++GC P T A++                    R GR       D
Sbjct: 222 --------------FPSIGCEPCTRAIKP---------------GEDLRAGRWWWENQSD 252

Query: 287 RDQAGSME 294
           ++    ME
Sbjct: 253 KECGLHME 260


>UniRef50_C4L4E5 Sulfurtransferase DndC n=3 Tax=Bacillales RepID=C4L4E5_EXISA
          Length = 551

 Score =  143 bits (360), Expect = 7e-33,   Method: Composition-based stats.
 Identities = 57/321 (17%), Positives = 97/321 (30%), Gaps = 48/321 (14%)

Query: 10  RQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTL-----PFPLLHV 63
             +   SI +I+ V    + P V+ +S GKDS++   L  +A    +         ++  
Sbjct: 16  DTVSRRSIDLIKRVYLNDTRPWVVGFSGGKDSTLTTQLIFEALLELSPEQLHKKVFIISS 75

Query: 64  DTGWKFREMYEFRD-------RTAKAYGCELLVHKNPEG---------VAMGINPFVHGS 107
           DT  +   +    +         A  Y   +   K             +  G        
Sbjct: 76  DTLVENPLVVSMINGSLHRMQEAAFKYNLPIETQKVKPLTEKTFWTNIIGRGYPTPNQTF 135

Query: 108 AKHTDIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQ 163
              TD +K +   + +     KYG      G R  E  SR +    S +D         +
Sbjct: 136 RWCTDRLKIDPANRFIKDKVSKYGEIIMVLGVRSSESTSRGQ----SIKDHEISGSELMR 191

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
              L + Y             P+  +   D+W Y+          +   ++  ++     
Sbjct: 192 HTSLANAY----------VFAPIKEFVLDDVWSYLLQNPAPWGEDHHKLQKMYMDSSSEC 241

Query: 224 MMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEM--LVSTTSERQ 281
            ++ D  I    G        RF   GCW  T   +  + T      E   L      R 
Sbjct: 242 PLVVDQNIKESAG---SCGNSRF---GCWTCTVVNQDKSLTGFIQTGEHDWLKPLLKFRN 295

Query: 282 GRVIDRDQAGSMELKKRQGYF 302
             V+ RD       K+  G F
Sbjct: 296 KMVLIRDDRSKRMHKRMNGAF 316


>UniRef50_B1VHQ3 Adenosine phosphosulfate reductase n=17 Tax=Corynebacterium
           RepID=B1VHQ3_CORU7
          Length = 283

 Score =  143 bits (359), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 44/284 (15%), Positives = 83/284 (29%), Gaps = 82/284 (28%)

Query: 14  AESIHIIREVAAE-FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A +  I+   A +      +  S+    +++  LA++AF        L+ +DTG+ F E 
Sbjct: 71  ASAAEILSWAAEQLDGPVAITLSMQ--DTILAELAQRAFDGQQADAELVFLDTGYHFPET 128

Query: 73  YEFRDRTAKAYGCELLVH-----KNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
            +      + Y   L        +  +    G N +         + K E L + L+   
Sbjct: 129 LDTAAAVEERYNLPLRRITPTLSRAEQDDVYGPNLYQRNPTACCRMRKVEPLARMLDP-- 186

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           F+A   G RR +   RA   +                                +++ P++
Sbjct: 187 FEAWVSGVRRVDSPLRANTPVIEVDRT------------------------GRLKLNPIA 222

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
            WT+ D+ ++I   ++ I PL                                       
Sbjct: 223 AWTDDDVQRFIEDNDLIINPLTKQGY---------------------------------P 249

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           ++GC   T  V                     R GR    ++  
Sbjct: 250 SIGCATCTLPVA---------------EGEDPRSGRWAGTNKTE 278


>UniRef50_Q8RG73 Phosphoadenosine phosphosulfate reductase n=3 Tax=Bacteria
           RepID=Q8RG73_FUSNN
          Length = 574

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 51/258 (19%), Positives = 88/258 (34%), Gaps = 36/258 (13%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +        L  E+   I++ A ++     V+ +S GKDS+V+  L   A   G      
Sbjct: 147 KANKFRYLYLVDEANEFIKKTAKKYEEEKIVISFSGGKDSTVVADLVINAL--GNPSLVH 204

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCEL-LVHKNPE----GVAMGINPFVHGSAKHTDIMK 115
           +  DT  +F+   E+ +R   ++   +  + KN E     V   I P          + K
Sbjct: 205 IFGDTTLEFQTTMEYAERYRASHRQAIFQIAKNNEQNFMSVCNDIGPPARMMRWCCSMFK 264

Query: 116 TEGLKQALNKYGFD---AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           T  + + LN    +     F G R+ E  SR+K                           
Sbjct: 265 TGPITRVLNNLYREERILTFYGIRKSESLSRSKYNRVEGNSE------------------ 306

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDN-RI 231
             +   +     P+  W++ DIW YI    ID    Y        +R G     ++N R 
Sbjct: 307 -SVKIQKQTVASPIFFWSDIDIWLYILTRKIDFNEAYRRGY----DRVGCWCCPNNNIRA 361

Query: 232 DLQPGEVIKKRMVRFRTL 249
                  + ++   +R  
Sbjct: 362 QFMSTIYMPEKSKEWRNF 379


>UniRef50_B0D4U7 Predicted protein n=2 Tax=Agaricales RepID=B0D4U7_LACBS
          Length = 320

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 51/317 (16%), Positives = 85/317 (26%), Gaps = 59/317 (18%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFY------ 52
           +       L  L  E++ +I             + ++ GKD +V+LHL   A        
Sbjct: 13  LANSPDDPLGPLVKEALEVIDHALDTHGQDGLSISFNGGKDCTVLLHLYAGAIARRLQLS 72

Query: 53  PGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHK-----NPEGVAMGINPFVHGS 107
               P   +++     F  +  F  +T K Y  +L   +         +  G        
Sbjct: 73  EEMKPIHSIYIPVPSPFPSLEAFISKTEKTYNLDLFSCRSALSQVDPTLTTGPGEP-GAP 131

Query: 108 AKHTDIMKTEGLKQALNKYG-----FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
                I   EG+  AL  Y        A   G RR +                       
Sbjct: 132 KAAGKIRPGEGMLHALAMYKERFPQVTAILIGTRRTD----------------------P 169

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
               L H            RV P+ NW+  D+W+++    +    LY      +      
Sbjct: 170 HGATLSHRNMTDPGWPCFERVNPIINWSYADVWKFLRQLEVPYCDLYDQGYTSLGSTYNT 229

Query: 223 LMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLP---------------- 266
                    + +P    K  +    +      T +  S +  +P                
Sbjct: 230 FPNPALLVPEQKPLVEGKTPLSTPVSP--ESCTSSTPSRSNGVPPVEPSRSSTTEDATPR 287

Query: 267 EIIEEMLVSTTSERQGR 283
                 L     ER GR
Sbjct: 288 YRPAYELTDGNLERCGR 304


>UniRef50_A8AAE7 Phosphoadenosine phosphosulfate reductase n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8AAE7_IGNH4
          Length = 648

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 46/247 (18%), Positives = 85/247 (34%), Gaps = 39/247 (15%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +     LR+L ++S   I  + ++   P+ + +S GKDS V LHL  +   P      ++
Sbjct: 204 KFNERRLRRLTSQSKRFIYSMVSKVEKPLTVSFSGGKDSLVALHLTLEFGKPI-----VV 258

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN---PFVHGSAKHTDIMKTEG 118
             +TG +  E  E   R  +A+  EL V          +    P          + K   
Sbjct: 259 FNNTGIEMPETVETVRRVVEAFDLELAVADAGNSFWEAMKRNSPPARDLRWCCKVTKLVP 318

Query: 119 LKQALNKYGFDAA--FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           + + + +          G R  E   R+K                               
Sbjct: 319 MAKLVKERWPSGTLNVVGQRAFESIERSKSPRV----------------------WRNKW 356

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENID--IVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
             + + + P+  WT+ D+W YI+ + +   + PLY        ER G  M       + +
Sbjct: 357 FPQVLNIAPIHYWTQLDVWMYIFQKGLKDLVNPLYFKG----FERIGCFMCPASLLAEFE 412

Query: 235 PGEVIKK 241
             + + +
Sbjct: 413 FTKRVHE 419


>UniRef50_A4YFD1 Phosphoadenylylsulfate reductase (Thioredoxin) n=3 Tax=Archaea
           RepID=A4YFD1_METS5
          Length = 238

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 52/300 (17%), Positives = 92/300 (30%), Gaps = 92/300 (30%)

Query: 1   MDQIRLTHLRQLEAE-----SIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPG 54
           M + +   +  L  E     +  II      F     +  S   +  V+L +A +     
Sbjct: 1   MSRFKEEEIAVLSREMETMSAERIIGWAVENFQDRLAIASSFQVEDMVILDIASRYG--- 57

Query: 55  TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEG------VAMGINPFVHG-- 106
                +  +DTG   +E Y+  D   + YG ++ V               G+N F +   
Sbjct: 58  --KVRVFTIDTGRLPQETYDLIDVVRERYGIKVEVFFPKPEDVEKMVREHGVNLFYNSVK 115

Query: 107 -SAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRP 165
                    K + LK+AL   G DA   G RR++ ++R+  R                  
Sbjct: 116 LRQMCCWNRKVKPLKRALE--GIDAWMTGLRREQWETRSSVRKIEVDTIH---------- 163

Query: 166 ELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
                       G  +++ PL++WT + +W+Y+  +++    LY                
Sbjct: 164 ------------GNIVKINPLADWTWEQVWKYVKEKDVPYNALYNKG------------- 198

Query: 226 IDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                               + ++GC P T  V                     R GR  
Sbjct: 199 --------------------YMSIGCLPCTRPVRP---------------GEHPRAGRWW 223


>UniRef50_B5IDE7 Phosphoadenosine phosphosulfate reductase family protein n=2
           Tax=Aciduliprofundum boonei T469 RepID=B5IDE7_9EURY
          Length = 423

 Score =  142 bits (358), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 48/228 (21%), Positives = 79/228 (34%), Gaps = 46/228 (20%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
              L +LR++E E+I  I+   A++    + +S GKDS   L+LA KA          ++
Sbjct: 185 SANLGYLRKIENEAIERIKRAKADY----VAFSGGKDSETALYLAYKAGVK-----RAIY 235

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAM---GINPFVHGSAKHTDIMKTEGL 119
            +TG +F E   F    A   G EL+  +           +          T  +K E L
Sbjct: 236 ANTGLEFPETERFAYNFADYLGIELIEIRPKVDFWEMVEKLGIPTKDRRWCTKYLKLEEL 295

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           K+            G+R+ E   R                              +   G 
Sbjct: 296 KKF-----KGTIVDGSRKYESIGRMLRP-------------------------QESKLGN 325

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
              ++P+ +W   D+W ++  + +   PLY        ER G  M   
Sbjct: 326 LRVIYPILDWLALDVWLFLEWKKLPHNPLYDMGY----ERIGCFMCPS 369


>UniRef50_D2RH85 Phosphoadenosine phosphosulfate reductase n=1 Tax=Archaeoglobus
           profundus DSM 5631 RepID=D2RH85_ARCPR
          Length = 396

 Score =  142 bits (357), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 48/236 (20%), Positives = 80/236 (33%), Gaps = 39/236 (16%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           +     L  +E  SI  IRE A    N  + +S GKDS   L LA+KA          ++
Sbjct: 200 EKNRMFLEVMERISIKFIREHAN---NVAVPFSGGKDSLACLILAKKALG----DVKAIY 252

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
           + T ++     E+ +R  K  G +L+V      V     P      +    +K E L++ 
Sbjct: 253 IKTNYEMPYTEEYIERVCKRLGVDLIVESVKFDVEKYGMP--THQNRWCTKLKMEALERV 310

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           +          G R  E + R +  +   R                              
Sbjct: 311 VKSEEVKTLIVGDRDAESRVRRERPVVFERIAKE-------------------------- 344

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
           +FP+  W+   +  YI +  +D+ PLY         R G  +    +  +    E 
Sbjct: 345 IFPIKYWSGAMVQLYILMNGLDLHPLYYKG----FYRLGCTICPSLSEWEKNLLES 396


>UniRef50_D2L597 Phosphoadenosine phosphosulfate reductase n=1 Tax=Desulfovibrio sp.
           FW1012B RepID=D2L597_9DELT
          Length = 274

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 61/324 (18%), Positives = 101/324 (31%), Gaps = 93/324 (28%)

Query: 9   LRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPFP-LLHVDTG 66
           L +  A    ++      F     + ++  KDS+++L L R+A    +LP P +L +D G
Sbjct: 14  LEEKIAAGKAVVLAAIDRFGPDFWLAWTGAKDSTLVLWLTREACRERSLPMPRVLTIDEG 73

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPE----------------------------GVAM 98
             F E+  F++R  + +G +L V  N +                            G   
Sbjct: 74  DPFPEIQAFQERMVREWGLDLTVAANTDVLSRRPAIGDYLAVADLSPESRAEVARAGFTG 133

Query: 99  GINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRW 158
              PF   S     +MK   +   L      A     R DE  +RA E            
Sbjct: 134 EGFPFDPESPVGNQLMKVAPMNGFLRDNHVAALATAIRWDEHPARANED----------- 182

Query: 159 DPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE 218
                       Y         +RV P+ +  E+D+W       I    LY    R +  
Sbjct: 183 ------------YESPREDPPHLRVHPILHLRERDVWDITRSRGIPFCELYAKGYRSLGT 230

Query: 219 RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTS 278
           + G +                                         LP   +++    + 
Sbjct: 231 KTGTV-------------------------------------RQSDLPAWEQDLE-DRSG 252

Query: 279 ERQGRVIDRDQAGSMELKKRQGYF 302
           ER GR  D+++  +ME  +  GY 
Sbjct: 253 ERAGR--DQEKEEAMEQLRSLGYM 274


>UniRef50_C2TXL3 Sulfurtransferase DndC n=1 Tax=Bacillus cereus Rock1-3
           RepID=C2TXL3_BACCE
          Length = 500

 Score =  141 bits (356), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 47/326 (14%), Positives = 96/326 (29%), Gaps = 47/326 (14%)

Query: 4   IRLTHLRQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPG-----TLP 57
           ++  +L++  A++ + I+ +    + P V+ YS GKDS+ ++ L   A            
Sbjct: 6   LKENNLQEFAADAKNEIKNIYLNDNRPWVIGYSGGKDSTAVVQLVFTALSELPREQVNKK 65

Query: 58  FPLLHVDTGWKFREMYEFRDRT-------AKAYGCELLVHKNPEGVA---------MGIN 101
             ++  DT  +   +    D+T       A         HK    +           G  
Sbjct: 66  VYVISSDTLVETPLIISSIDKTLHRIQEKALELDLPFETHKVKPDIKSTFWTSIIGKGYP 125

Query: 102 PFVHGSAKHTDIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHR 157
                    TD MK     + +     K+G      G R  E ++RA+  +        +
Sbjct: 126 SPRQKFRWCTDRMKINPANRFIKDKVSKFGEVIMVLGVRESESQTRAE--VMRSHTTDGK 183

Query: 158 WDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVL 217
              ++                 +    P+  +T  ++W+Y+  ++          +    
Sbjct: 184 TLMRHSTL------------PNAYVYAPIRKFTLDNVWEYLLNDSSPW------GDNNHE 225

Query: 218 ERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTT 277
                     +  + +                GCW  T   +  A        E  +   
Sbjct: 226 LLGLYQSSNSECPLIVDKEIKESAGSCGNSRFGCWTCTVVKKDKALAGFIDNGEEWLKPL 285

Query: 278 SE-RQGRVIDRDQAGSMELKKRQGYF 302
            E R      RD     +  +  G+ 
Sbjct: 286 LEFRNWLSEIRDVREYRQKTRMNGHM 311


>UniRef50_C1AUL1 Phosphoadenosine phosphosulfate reductase n=11 Tax=Actinomycetales
           RepID=CYSH_RHOOB
          Length = 247

 Score =  141 bits (355), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 53/293 (18%), Positives = 94/293 (32%), Gaps = 93/293 (31%)

Query: 14  AESIHIIREVAAEFS----------NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
           A +  +++     F           N  ++ S  +D  V++HLA +          +L +
Sbjct: 27  ASARELLQWTEETFGSGASEGTGYRNSFIVASNMQDG-VLVHLAAQV----HPGVDVLFL 81

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEG 118
           DTG+ F E    RD   + YG  ++  +       +  A G + F     +   + K   
Sbjct: 82  DTGYHFAETIGTRDAVEQVYGVNVINARAEASVAEQDAAEGKDLFAREPNRCCALRKVAP 141

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           LK+ L   G+ A   G RR E  +RA   + SF D F                       
Sbjct: 142 LKKTLA--GYKAWVTGIRRVEAPTRANAPLISFDDAFG---------------------- 177

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +++ P++ W+++D+  YI   +I + PL                              
Sbjct: 178 -LVKINPIAAWSDEDMQSYIDEHSILVNPLVDEGYP------------------------ 212

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                    ++GC P T                     +  R GR   + +  
Sbjct: 213 ---------SIGCAPCTSK---------------PAPGSDPRSGRWAGQAKTE 241


>UniRef50_C4LKR1 Adenosine phosphosulfate reductase n=5 Tax=Actinomycetales
           RepID=C4LKR1_CORK4
          Length = 297

 Score =  141 bits (354), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 47/297 (15%), Positives = 88/297 (29%), Gaps = 86/297 (28%)

Query: 1   MDQIRLTHLRQLE-AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           M  + L +  +LE A +  I++          +  S+    +V+  LA K      L   
Sbjct: 76  MLNLALDYSAELEKASAEEIMQWAHDYVPKLAVTLSMQ--DTVLADLAEKYAPAADL--- 130

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIM 114
            + +DTG+ F E  +  D   + Y   LL          +    G + +         + 
Sbjct: 131 -VFLDTGYHFAETLDVADAVERRYSNRLLRVVPHLTRREQDQRYGKDLYATDPTLCCHMR 189

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K   L++ L   G+ A   G +R +  SRA   +                          
Sbjct: 190 KVVPLQETLA--GYPAWVTGLKRVDAPSRAHTPVLEIDKA-------------------- 227

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                 +++ P+  WT+ D+  YI   ++   PL                          
Sbjct: 228 ----GRLKINPIITWTDDDVENYIVEHDLIRHPLTTQG---------------------- 261

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                      + ++GC   T  V+               +    R GR   +++  
Sbjct: 262 -----------YPSIGCATCTARVQ---------------AGEDPRSGRWQGKEKTE 292


>UniRef50_A3DN95 Phosphoadenosine phosphosulfate reductase n=2
           Tax=Desulfurococcaceae RepID=A3DN95_STAMF
          Length = 656

 Score =  141 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 44/240 (18%), Positives = 73/240 (30%), Gaps = 36/240 (15%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
               +   + ++I  +R++  +     V+ YS GKDS   L+L  +A         LL  
Sbjct: 202 NEYGIEFYKEKAIKFLRKLYEKNKLPVVVSYSGGKDSLTALNLTLEALG----DAELLFN 257

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMG---INPFVHGSAKHTDIMKTEGLK 120
           DTG +  E  +  +  +K YG +L+     +          P          I K   + 
Sbjct: 258 DTGLELPETIKNVEYVSKHYGLKLVKASAGDAFWKAVWIFGPPGKDYRWCCKITKLVPIA 317

Query: 121 QALN-KYGFDAA-FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           +    K+G  A    G R  E   RA+                                 
Sbjct: 318 RVTKAKWGNGALNIVGQRAYESIDRARSPSV----------------------WRNRWVP 355

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             +   P+  W +   W YI    +    LY        ER G  +       + +  E 
Sbjct: 356 HLLSASPIQEWNQLVEWLYITKYKLPYNKLYDMG----FERLGCYVCPSSTLAEFKEIEK 411


>UniRef50_A2EL13 Putative uncharacterized protein n=2 Tax=Trichomonas vaginalis
           RepID=A2EL13_TRIVA
          Length = 215

 Score =  141 bits (354), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 43/227 (18%), Positives = 79/227 (34%), Gaps = 43/227 (18%)

Query: 6   LTHLRQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
           +  L      +  +I+E    +       Y+ GKDS V+L L               +++
Sbjct: 4   INGLDAKILSAKSVIKEAFERYSDKLSFCYNGGKDSVVLLDLVMNVVKENNYTIKPFYLE 63

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
            G +F E+ +F + + K +G +L+  K                      +K EGL++ +N
Sbjct: 64  VGDEFDEILDFINYSEKYWGFKLMRIKA-------------------TNLK-EGLEKLIN 103

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            Y  ++ F G R D+  +  K + +                             E+ R+ 
Sbjct: 104 TYQINSVFLGVRADDYPN-IKMKPFE---------------------PTNNGWPEAERIM 141

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
           P+ +WT  DIW+YI   N+    LY      +  +            
Sbjct: 142 PILDWTYNDIWEYIDKFNLPFCSLYNLGYTSIGPKSKTHPNPLLKDP 188


>UniRef50_B4WAM0 Phosophoadenylyl-sulfate reductase subfamily, putative n=7
           Tax=Alphaproteobacteria RepID=B4WAM0_9CAUL
          Length = 359

 Score =  140 bits (353), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 47/285 (16%), Positives = 93/285 (32%), Gaps = 86/285 (30%)

Query: 14  AESIHIIREVA--AEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
            ++  I++     A       + S G +S+ +LH+  +         P++ ++TG  F +
Sbjct: 142 KDASEILKAALDPALGLRVGAISSFGAESAALLHIVAE----TDRDVPVVFLETGQHFLQ 197

Query: 72  MYEFRDRTAKAYGCELLVHKNPEG-----VAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
              +R +  KA G   +    P+      +    + +   +    D+ K   L  A    
Sbjct: 198 TLSYRIQLTKALGLTDVRLVTPDANEKATLDARNDLWRTDADACCDLRKVRPLAHA--TV 255

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           GF+A   G +R +  +RA  + +   D                           +R+ PL
Sbjct: 256 GFNAVITGRKRYQAATRAALKPFEVLD-------------------------GVLRINPL 290

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
           ++W  +D+  ++   ++   PL                                      
Sbjct: 291 ADWDAEDVEAWLEAHDLPRHPLVEQGY--------------------------------- 317

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           R++GCWP T AV+ + +                R GR    D+  
Sbjct: 318 RSIGCWPCTRAVQDDEEA---------------RAGRWPGMDKVE 347


>UniRef50_C4XSH1 Putative adenylyltransferase n=1 Tax=Desulfovibrio magneticus RS-1
           RepID=C4XSH1_DESMR
          Length = 270

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 60/333 (18%), Positives = 99/333 (29%), Gaps = 94/333 (28%)

Query: 1   MDQIRLT-HLRQLEAESIHIIREVAAEFSNPV-MLYSIGKDSSVMLHLARKAFYPGTLPF 58
           MD   L   L    A S  ++      F +   + ++  KDS++ L LAR+         
Sbjct: 1   MDHALLDLPLDDKIALSKRVLAGAMDRFGHTFWIAWTGAKDSTLTLWLARELCRETGRTM 60

Query: 59  P-LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMG------------------ 99
           P +L +D G  F E+ +F+ R    +G ++ +  N E +                     
Sbjct: 61  PRVLTIDEGDPFPEILDFQKRLTADWGLDVHLAANHEILDRKPAIGDYIDLSGLSQAVRD 120

Query: 100 ----------INPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIY 149
                       PF   S     +MK   +   L + G  A     R DE  +R  E   
Sbjct: 121 EAARTGFTGPGFPFDPESPLGNQLMKVLPMNTFLRENGVAALATAIRWDEHPAREGE--- 177

Query: 150 SFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLY 209
                                Y     +   +RV P+ +  E D+W       +    LY
Sbjct: 178 --------------------LYESPREEPPHLRVHPILHMREADVWAITRGRGLPHCSLY 217

Query: 210 LAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEII 269
               R +    G +                                         LP   
Sbjct: 218 AKGYRSLGTLSGTV-------------------------------------RKSDLPAWE 240

Query: 270 EEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF 302
           +++    + ER GR  D++   +ME  +  GY 
Sbjct: 241 QDLD-DRSGERAGRDQDKED--AMEQLRALGYM 270


>UniRef50_C0CT99 Putative uncharacterized protein n=1 Tax=Clostridium asparagiforme
           DSM 15981 RepID=C0CT99_9CLOT
          Length = 450

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 47/312 (15%), Positives = 94/312 (30%), Gaps = 47/312 (15%)

Query: 17  IHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFYPGTLP-----FPLLHVDTGWKFR 70
           +  ++ V      P ++ +S GKDS+V++ L  +               ++  DT  +  
Sbjct: 1   MEEMKLVYLHDKRPWMVGFSGGKDSTVLVSLIFEMLNSLDPKQRHKMVHIVSSDTMVENP 60

Query: 71  EMYEFRDRTAKAYGC---------ELLVHKNPEGVAMGI------NPFVHGSAKHTDIMK 115
            + ++    +              +++  +  +     +       P   G    T+ +K
Sbjct: 61  IVRDYMHDVSNMINIFGKSLRVDAKIIYPRVEDTFWCRVIGLGYPTPEPPGFRWCTERLK 120

Query: 116 TEGLKQA----LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
              + +     + K G      G R+ E   RA+                  R       
Sbjct: 121 IHPMNRFTVNTIKKNGEIVLLLGVRKAESSYRAR--------------NIKNREIDGKLL 166

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
               +   +    PL+      +W+Y+  ++              L +   L        
Sbjct: 167 VPHSDIENAYVYNPLTEIPNDVVWKYLLKDDGKSPWGTSNKYLFSLYQGENLGEEASVIG 226

Query: 232 DLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRV---IDRD 288
           ++   ++      RF   GCW  T   E  +  L   IE+        R  R      R 
Sbjct: 227 EVDKDKIPVTGNSRF---GCWVCTMVKEDKS--LKNFIEKGEKWLEPLRDFRNELLELRS 281

Query: 289 QAGSMELKKRQG 300
             G+ E K+R G
Sbjct: 282 DPGAREDKRRNG 293


>UniRef50_Q2G577 Phosphoadenylylsulfate reductase (Thioredoxin) n=8
           Tax=Alphaproteobacteria RepID=Q2G577_NOVAD
          Length = 270

 Score =  140 bits (353), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 54/297 (18%), Positives = 93/297 (31%), Gaps = 83/297 (27%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           D IRL +L     ++  ++R V  +    +  ++ S G +S+V+LHL  +         P
Sbjct: 22  DAIRLNNL-FRGTDTHDMLRSVIRDGLAGDLAVVSSFGAESAVLLHLIAEV----DPSVP 76

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGC-ELLVHKNPEGV----AMGINPFVHGSAKHTDIM 114
           +L ++TG  FRE   +RD      G   L + +    V          +        +I 
Sbjct: 77  VLFLETGKHFRETVAYRDELIGFLGMTNLQIIEPDAAVIAKKDENGLRWSWDPDGCCEIR 136

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E L +AL    FDA+  G +  + K+RA    +       +                 
Sbjct: 137 KVEPLARAL--LHFDASITGRKGFQSKTRAGLPRFEIDRSDAQ----------------- 177

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                 +++ PL++W +  +  Y     +   PL                          
Sbjct: 178 ----GRLKINPLASWDKTMLEAYFAEHGLPPHPLVAQGY--------------------- 212

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                        ++GC P T  V                     R GR    D+  
Sbjct: 213 ------------PSIGCAPCTSKVAP---------------GEDPRSGRWKGWDKTE 242


>UniRef50_C1A1H0 Phosphoadenosine phosphosulfate reductase n=21 Tax=Actinomycetales
           RepID=CYSH_RHOE4
          Length = 247

 Score =  140 bits (352), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 45/248 (18%), Positives = 87/248 (35%), Gaps = 51/248 (20%)

Query: 14  AESIHIIREVAAEFSN-----------PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           A +  +++     F +            ++  ++     V++HLA +          +L 
Sbjct: 27  ASAQELLQWTEDTFGDGASAATGDRNGYIVASNM--QDGVLVHLAAQV----HPGVDVLF 80

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTE 117
           +DTG+ F E    RD   + YG  ++  +       + VA G + F     +   + K  
Sbjct: 81  LDTGYHFPETIGTRDAVEQVYGVNVINARALASVAEQDVAEGKDLFARDPNRCCALRKVA 140

Query: 118 GLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
            LKQ L+  G+ A   G RR E  +RA   + SF + F                      
Sbjct: 141 PLKQTLS--GYSAWVTGIRRVEAPTRANAPLISFDEAFG--------------------- 177

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
              +++ P++ W+++++  YI   +I + PL       +    G             P  
Sbjct: 178 --LVKINPIAPWSDEEMQNYIDTNSILVNPLVDEGYPSI----GCAPCTSKPAPGSDPRS 231

Query: 238 VIKKRMVR 245
                  +
Sbjct: 232 GRWAGASK 239


>UniRef50_A8AC84 Phosphoadenosine phosphosulfate reductase n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8AC84_IGNH4
          Length = 646

 Score =  140 bits (352), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 44/235 (18%), Positives = 78/235 (33%), Gaps = 35/235 (14%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           +    +L++L   S  ++ +        ++  S GKDS+    L  +      +   LL 
Sbjct: 192 KANEAYLQELLEWSRQVVSKAPE--GVRIVSLSGGKDSA----LVTQILKELGVEAKLLF 245

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN---PFVHGSAKHTDIMKTEGL 119
            DTG +  E  +  +  AK +G EL+V    +     +    P          ++K   +
Sbjct: 246 NDTGIELPETVKTAEEEAKHFGMELIVASAGDLFWRAVELFSPPARDFRWCCKVLKLGPI 305

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
            + L K+G    F G R  E   RAK         F                        
Sbjct: 306 ARTLIKFGNVVNFVGNRWWESLERAKATPIMKMKYF----------------------PT 343

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
              V P+  W +   + Y+  + + + PLY        +R G  M       + +
Sbjct: 344 ITTVNPILPWPQLLEFAYLIDKGVPLNPLYFKG----FDRVGCFMCPGATAWEFK 394


>UniRef50_Q2JFN1 Phosphoadenylylsulfate reductase (Thioredoxin) n=1 Tax=Frankia sp.
           CcI3 RepID=Q2JFN1_FRASC
          Length = 223

 Score =  140 bits (352), Expect = 7e-32,   Method: Composition-based stats.
 Identities = 51/289 (17%), Positives = 93/289 (32%), Gaps = 90/289 (31%)

Query: 10  RQLE-AESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
             LE A +  I+R    EF     +  S+    ++++ +  +         P++ +DTG+
Sbjct: 14  DDLEGAPAEEILRWAVGEFGTKLAIAASMA--EAILVDMLARI----RSDVPVVFIDTGY 67

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
            F E    RD  A  Y   ++  +       +    G + +         + K   L +A
Sbjct: 68  HFPETVGTRDAVAGTYDLPIISARPQLTVVGQDAVYGQDLYRTDPDLCCRMRKVVPLDRA 127

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           L  Y   A   G+RR E  SRAK R+  +  R  +                        +
Sbjct: 128 LAPY--RAWAAGSRRAESPSRAKLRVVDWDARRGKV-----------------------K 162

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           + PL+ WT++D+ +Y+    + + PL                                  
Sbjct: 163 IHPLAAWTDEDVERYVAEHGVIVNPLLSDG------------------------------ 192

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
              + ++GCWP T                        R+GR +   +  
Sbjct: 193 ---YDSVGCWPCTRRGAG-------------------REGRWVGSIKTE 219


>UniRef50_B8CCL3 Phosphoadenosine-phosphosulphate reductase n=1 Tax=Thalassiosira
           pseudonana RepID=B8CCL3_THAPS
          Length = 438

 Score =  139 bits (351), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 38/237 (16%), Positives = 77/237 (32%), Gaps = 31/237 (13%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           + + +   L+ LE +++  ++     + N V   ++    SV+ HL  +  Y       +
Sbjct: 58  IAESKEMRLKHLEEQAMFALKIAVENYGNAVFPNALIAGDSVITHLLHRMGYLKDGQAKV 117

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNP---------EGVAMGINPFVHGSAKHT 111
           + VDT   F E  EF       YG +  +                  G + +     ++ 
Sbjct: 118 MVVDTFHLFPETMEFLREIEDFYGFKAEIFCAEGVPVGDKAAYDKKYGADLWKEDIEQYD 177

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            + K E  ++ L     D    G  R +   RA                          +
Sbjct: 178 KVCKVEPFQRGLKTLNTDCMINGRTRWQGFERA----------------------WIDQF 215

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
                 G   +  P++ WT +D + YI    +   PL+      + +    + + +D
Sbjct: 216 ENAPIGGGLAKCNPIAYWTLEDTFDYIAKYEVPHHPLHAKGYPSIGDAKDTIPIPED 272


>UniRef50_P56859 Phosphoadenosine phosphosulfate reductase n=12 Tax=Saccharomyceta
           RepID=MET16_EMENI
          Length = 302

 Score =  139 bits (351), Expect = 8e-32,   Method: Composition-based stats.
 Identities = 47/300 (15%), Positives = 83/300 (27%), Gaps = 67/300 (22%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
            L+ LE     ++R       +     + G    V++ +  K   P      L+ +DT  
Sbjct: 48  QLQFLE--PQDVLRWCVTSLPHLYQTTAFGLTGLVIMDMLSKLSIPRPQMVNLIFLDTLH 105

Query: 68  KFREMYEFRDRTAKAYGC-ELLVHKN-------PEGVAMGINPFVHGSAKHTDIMKTEGL 119
            F E  +  D   K Y    + V+K              G   +      +  I K E  
Sbjct: 106 HFPETLKLVDNVRKRYPLQHIHVYKPQGVETEEEFAKKHGERLWEKDDQLYDWIAKVEPA 165

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           ++A  +    A   G RR +   R    I    +                          
Sbjct: 166 QRAYRELNVHAVLTGRRRSQGGKRGDLDIIEVDEA------------------------G 201

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
            I++ PL+NWT   + QY+   +I    L     +                         
Sbjct: 202 LIKINPLANWTFDQVKQYVKENDIPYNELLDKGYK------------------------- 236

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQ 299
                   ++G +  T  V+ N        +    +       R         ME K+++
Sbjct: 237 --------SVGDYHSTSPVKENEDERSGRWKGQAKTECGIHNPRSKYAQYLMDMERKRQE 288


>UniRef50_A1ZIJ8 Phosphoadenosine phosphosulfate reductase n=2 Tax=Microscilla
           marina ATCC 23134 RepID=A1ZIJ8_9SPHI
          Length = 476

 Score =  139 bits (351), Expect = 9e-32,   Method: Composition-based stats.
 Identities = 57/328 (17%), Positives = 98/328 (29%), Gaps = 56/328 (17%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTL--- 56
           D  ++    Q+E     I+ +   E +N   ++ +S GKDS+++L L  K          
Sbjct: 5   DPTKMNIKEQVEQIKKEILEQYREEDNNRPWIIGFSGGKDSTMLLQLVWKTIQDNVPQDL 64

Query: 57  ---PFPLLHVDTGWKFREMYEFRDRTAKAY-------GCELLVHKNPEG---------VA 97
              P  ++  +T  +  ++  F +RT +         G  + V +             + 
Sbjct: 65  RTRPIHVICNNTLVENPKILSFVERTLEKIREASLAQGMPMTVEQTTPKLESSFWVNLIG 124

Query: 98  MGINPFVHGSAKHTDIMKTEGLKQALNK----YGFDAAFGGARRDEEKSRAKERIYSFRD 153
            G           T+ +K     Q +      YG      G R DE   RAK        
Sbjct: 125 KGYPAPNTIFRWCTERLKINPTTQYIKDKISNYGEVIILLGTRSDESSQRAK-------- 176

Query: 154 RFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAE 213
                    +R E+        +   +    P+ +   +D+W Y+   N          +
Sbjct: 177 -------NIKRHEIKGQRLRTHSLANAYAFTPIKDVLTKDVWTYLQAVNPP-----WEGD 224

Query: 214 RPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEML 273
              L    M     D    +           RF   GCW  T      +        E  
Sbjct: 225 NKELITLYMSSSGGD-CPIITDISTPSCGNSRF---GCWVCTVVKRDKSMEGLIESGEDW 280

Query: 274 VSTTSE-RQGRVI--DRDQAG-SMELKK 297
           +    E R       DRD     +E  +
Sbjct: 281 MVPLVEIRDFLSKTVDRDHPEYDLEKYR 308


>UniRef50_Q2W561 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase/FAD
           synthetase and related enzyme n=3 Tax=Magnetospirillum
           RepID=Q2W561_MAGSA
          Length = 232

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 45/266 (16%), Positives = 82/266 (30%), Gaps = 81/266 (30%)

Query: 28  SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGC-E 86
            +  +  S G +S+V+L L  +         P++ +DT   F E   +R +     G   
Sbjct: 31  GHIAVTSSFGAESAVLLDLVAEV----DPGLPVIFLDTDELFDETIAYRTQLECHLGLTN 86

Query: 87  LLVHKNPEGVAMG-INPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAK 145
           ++V +  +         +     +  ++ K   L +A+  YG  A   G +R     R  
Sbjct: 87  VIVVRPTKAELRDAEELWRTDEDRCCELRKVRPLARAVAGYG--ALVDGRKRAHGAEREG 144

Query: 146 ERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDI 205
               S                           G  ++V PL+ W+ ++I  +    N+  
Sbjct: 145 LATLS-------------------------GGGGVLKVSPLAKWSAEEIEAHFIRRNLPR 179

Query: 206 VPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTL 265
            PL   +                                  R++GCWP T  VE      
Sbjct: 180 HPLVAQSY---------------------------------RSIGCWPCTRPVE------ 200

Query: 266 PEIIEEMLVSTTSERQGRVIDRDQAG 291
                    +  S R GR   + ++ 
Sbjct: 201 ---------AGQSPRAGRWAGKGKSE 217


>UniRef50_Q3B2L6 Phosphoadenylylsulfate reductase (Thioredoxin) n=2
           Tax=Chlorobium/Pelodictyon group RepID=Q3B2L6_PELLD
          Length = 250

 Score =  139 bits (350), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 46/272 (16%), Positives = 85/272 (31%), Gaps = 75/272 (27%)

Query: 15  ESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           +   ++     +F   +     S G +  V++ +  +      L  P+  +DTG   +E 
Sbjct: 17  QPEEVLSRAVRKFGISHLAFASSFGAEDQVIIDMICR----HGLDIPVFTIDTGRLPQET 72

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVAM------GINPFVHG---SAKHTDIMKTEGLKQAL 123
           Y+  D T   YG  + V               G N F              K + L++ L
Sbjct: 73  YDLLDATRMHYGISMEVLFPERAPVEDMLQRFGANLFYDSVEKRRMCCRTRKVQPLERRL 132

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           +    DA   G RR++  +R    +  + + F                          ++
Sbjct: 133 SSL--DAWICGLRREQSVTRTGTGVVEWDEAFG-----------------------LFKI 167

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL+ +TE +++ Y+   N+    L+                                  
Sbjct: 168 NPLAAFTEAEVFGYLLRHNVPSNALHRKG------------------------------- 196

Query: 244 VRFRTLGCWPLTGAVESNAQ--TLPEIIEEML 273
             + ++GC P T AVE  A   +     EE  
Sbjct: 197 --YPSIGCAPCTRAVEPGADIRSGRWWWEEAE 226


>UniRef50_C6WVG4 Adenylylsulfate reductase, thioredoxin dependent n=2
           Tax=Betaproteobacteria RepID=C6WVG4_METML
          Length = 259

 Score =  139 bits (349), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 50/290 (17%), Positives = 85/290 (29%), Gaps = 88/290 (30%)

Query: 10  RQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +Q   E + ++   A EF         S G +  V+  + ++      +   +  +DTG 
Sbjct: 35  KQKADEVLALLSSAANEFGANEVTFANSFGAEDMVLTDIIQR----QKIAIEIFSLDTGR 90

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAM------GINPFVHG---SAKHTDIMKTEG 118
              E Y+   +T + Y  +L +               GIN F            + K E 
Sbjct: 91  LPVETYDLIAKTEQTYNTKLKIFFPQSDAVESYVRTNGINAFYESIDLRKACCFMRKVEP 150

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L++AL      A   G R ++  +R       F                           
Sbjct: 151 LQRALKD--KKAWVTGMRAEQSTTRVNLPFREFDSGNQ---------------------- 186

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
              +  PLSNWTE+++W YI + ++    L+                             
Sbjct: 187 -LEKFNPLSNWTEKEVWAYIRMFDVPYNKLHDQF-------------------------- 219

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRD 288
                  + ++GC P T A+                     R GR    D
Sbjct: 220 -------YPSIGCAPCTRAIA---------------MGEDVRAGRWWWED 247


>UniRef50_A3DLJ9 Phosphoadenosine phosphosulfate reductase n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DLJ9_STAMF
          Length = 457

 Score =  139 bits (349), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 44/235 (18%), Positives = 81/235 (34%), Gaps = 34/235 (14%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLH 62
           +     L   E  SI I+ +        ++ +S GKDS+  L L  K F         ++
Sbjct: 216 EANKQVLSLYEKISIKILEKYREWADTIIVPWSGGKDSTATLLLTLKVFSKN--KVKTIY 273

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKN--PEGVAMGINPFVHGSAKHTDIMKTEGLK 120
            DTG +F   +++ +  A+  G E++       +G+     P      +     K + ++
Sbjct: 274 ADTGTEFPWTHKYINEIAERLGVEVIRVYAGIDKGILDEGYPMPRHDNRWCTYRKIKAIE 333

Query: 121 QALNKY--GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           + + K   G      G R  E ++R+        +                         
Sbjct: 334 ETIGKLSDGNILLVKGDRDGESRARSMRPPIYVENE------------------------ 369

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
             I V P+  W+   I  Y+ L NI++ PLY         R G  +       ++
Sbjct: 370 NKIVVTPIKFWSAAHIQLYMLLNNIELNPLYYKG----FYRIGCYICPALRSWEV 420


>UniRef50_C1SHC5 PAPS reductase/FAD synthetase family protein n=1 Tax=Denitrovibrio
           acetiphilus DSM 12809 RepID=C1SHC5_9BACT
          Length = 764

 Score =  138 bits (348), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 59/299 (19%), Positives = 106/299 (35%), Gaps = 51/299 (17%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV----MLYSIGKDSSVMLHLARKAFYPGTL 56
           M +     L  +E  ++  I  V  ++ + +    + +S GKDS+V+L L +KA   G+ 
Sbjct: 110 MVESNREMLDIIEQSTVKKIISVYTKYKDKLDLFHVAFSGGKDSAVLLDLVKKALPLGS- 168

Query: 57  PFPLLHVDTGWKFREMYEFRDR---TAKAYGCELLVHKN---PEGVAMGINPFVHGSAKH 110
            F ++  DTG +F + Y+  D+     +A G    + K+   P+   +   P        
Sbjct: 169 -FVVVFGDTGMEFPDTYDVIDKTRQMCEADGIPFYIAKSSLEPQESWVLFGPPSRALRWC 227

Query: 111 TDIMKTEG----LKQALNKYGFDAA-FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRP 165
             + K+      L+    K  +    F G R +E   RA        +  +    K QR 
Sbjct: 228 CGVHKSAPQTLKLRAVTGKNDYTGLAFVGVRSEESAKRA--------EYDYENYSKKQRG 279

Query: 166 ELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
           +  H                +  WT  ++W Y++  NI I   Y         R G L  
Sbjct: 280 QYSH--------------NSILEWTSAEVWLYLYANNIMINEAYKKGNA----RAGCLFC 321

Query: 226 IDD-NRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                + D    ++  + +  +  +         +SN +              S R GR
Sbjct: 322 PMSVKKADFVKQQIYPREIKTYLDI-------IKKSNGRDFGGNSYLADGGWVSRRSGR 373


>UniRef50_A1VQ08 Phosphoadenylylsulfate reductase (Thioredoxin) n=7
           Tax=Proteobacteria RepID=A1VQ08_POLNA
          Length = 264

 Score =  138 bits (346), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 57/284 (20%), Positives = 87/284 (30%), Gaps = 85/284 (29%)

Query: 11  QLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFR 70
           Q  A S+ +I+  A E+S      S+G +  V+ HL  +A         +  +DTG    
Sbjct: 16  QKLAHSLALIKTAATEYSPLTQASSLGCEDMVITHLMHEAGLD-NASASIFVLDTGMLHL 74

Query: 71  EMYEFRDRTAKAYGCELLVHKNPEGVA---------MGINPFVHGSAKHTDIMKTEGLKQ 121
           E      R  + Y  ++ V+      A           +   +    +   I K E L++
Sbjct: 75  ETVALIGRIEERYPFKVDVYHPDADAASAFVEENGSQAMYKSLALRKQCCHIRKMEPLER 134

Query: 122 ALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
           AL   G      G RR++  +RA+                               + E  
Sbjct: 135 ALA--GKKGWLTGLRREQSAARAEVHDIE-------------------------QQPERA 167

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
           ++ PL  WT+ DIW YI L  I   PL+                                
Sbjct: 168 KINPLVEWTQGDIWHYIALNEIPYNPLHDQF----------------------------- 198

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
               F ++GC P T AV                     R GR  
Sbjct: 199 ----FPSIGCAPCTRAV---------------TLGEDFRSGRWW 223


>UniRef50_A2C6A4 Phosphoadenosine phosphosulfate reductase n=27 Tax=cellular
           organisms RepID=A2C6A4_PROM3
          Length = 266

 Score =  137 bits (344), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 44/237 (18%), Positives = 83/237 (35%), Gaps = 39/237 (16%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           ++  R+ HL +L   + + +     +F    V+  S G  S+V+LH+       G    P
Sbjct: 33  LEDARI-HLAKL--SAQNRLEWALKQFGQGFVLTTSFGIQSAVLLHMLH--GLDGGSVVP 87

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVH--------GSAKHT 111
           ++ VDTG+   E Y + D+  +  G +L V ++    A     +              + 
Sbjct: 88  VVWVDTGYLPAETYFYADQLTRQLGLDLKVVQSSMSPARMEAIYGRLWETGSVKDLETYH 147

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            I K E L+QAL+         G R D+   R                            
Sbjct: 148 RIRKVEPLEQALDDLHVHCWASGVRSDQTDYRRSMAFLDLIR------------------ 189

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
                  + + + PL +WT ++++ Y+    +   PL+      V +         +
Sbjct: 190 -------DRLSLRPLLDWTPKEVFYYMQEHQLPQHPLFEKGYSTVGDLHSSAPDGGE 239


>UniRef50_A9A540 Adenylylsulfate reductase, thioredoxin dependent n=14 Tax=Archaea
           RepID=A9A540_NITMS
          Length = 241

 Score =  136 bits (343), Expect = 8e-31,   Method: Composition-based stats.
 Identities = 43/294 (14%), Positives = 81/294 (27%), Gaps = 86/294 (29%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAE-FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
            Q ++  L      +   ++ V+           S G + +V++ +  K        F  
Sbjct: 5   TQEQVDDLNSKIKTAEEALQWVSDNLHPKVAKASSFGAEDAVIMDMMLKI----NPEFRF 60

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNP------EGVAMGINPFVH---GSAKHT 111
             +DTG   +E Y+  D   K Y   + V               G+N F           
Sbjct: 61  FTLDTGRLPQETYDIMDVLRKKYHITIEVLFPDTKEVEDMVKEKGLNLFYESVENRKLCC 120

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
           +I K   + + L+    D    G RR++ K R    ++                      
Sbjct: 121 EIRKVHPMNKMLSTL--DGWITGLRREQTKIREDVTMFQLD------------------- 159

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                 G  +++ P+ +WT   I ++I   ++    L                       
Sbjct: 160 ---HGHGGILKINPIIDWTWDQIQEHIKKYDLPYNSLLDKG------------------- 197

Query: 232 DLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                         + ++GC P T  ++                    R GR  
Sbjct: 198 --------------YPSIGCEPCTRPIKP---------------GEDIRAGRWW 222


>UniRef50_B2GI28 Adenosine 5'-phosphosulfate reductase n=24 Tax=Actinomycetales
           RepID=B2GI28_KOCRD
          Length = 287

 Score =  136 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 41/297 (13%), Positives = 78/297 (26%), Gaps = 84/297 (28%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           + +         +A+   ++   A  F     +  S+  D +V+  L             
Sbjct: 64  LVEEARERFGARDADPDEVLAWAAETFGPRLAVACSMASD-TVVPALVSTHLK----NVD 118

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVH-----KNPEGVAMGINPFVHGSAKHTDIM 114
           +L ++TG+ F E  + RD  A+ +   +           +    G             + 
Sbjct: 119 VLFLETGYHFPETLQTRDDFARDWPVNVRTLLPELTVPEQDAKYGAQLHDRDPGLCCGMR 178

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K   L +AL   G++A   G RR+E   RA      +                       
Sbjct: 179 KVAPLDKALA--GYEAWVTGLRREETPHRANAAPVEWD---------------------- 214

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
               + +++  + +WT   +  Y     + + PL                          
Sbjct: 215 -EHHQMVKINAIVDWTFDHVVAYAEENLVVVNPLLSQGY--------------------- 252

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                        ++GC P T  V                     R GR     +  
Sbjct: 253 ------------PSIGCAPCTRKVAP---------------GEDPRAGRWSGVGKTE 282


>UniRef50_C5ETD1 Phosphoadenosine phosphosulfate reductase n=4 Tax=Clostridiales
           RepID=C5ETD1_9FIRM
          Length = 286

 Score =  136 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 44/249 (17%), Positives = 73/249 (29%), Gaps = 28/249 (11%)

Query: 11  QLEAESIHIIREVAAEFSN-----PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
            LE +SI  I+  +           +  YS GKDS V+L L  +      + F   +  T
Sbjct: 2   DLETKSIERIKLASEMSKRYYDAPIICTYSGGKDSDVLLDLFIR----SGVEFEAHNSHT 57

Query: 66  GWKFREMYEFRDRT---AKAYGCELLVHKNPEGVA----MGINPFVHGSAKHTDIMKTEG 118
                +   +        K  G   ++H  P  +         P         +I+K   
Sbjct: 58  TVDAPDTVYYIREKFRGLKEKGIPCIIHMPPLSMWQLIVKKKMPPTRMQRYCCEILKE-- 115

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQR-PELWHNYNGQINK 177
                N         G R DE   R+K                     +       +   
Sbjct: 116 -----NTTPDRLVSTGVRWDESTKRSKRGQLEAAAPKVENRITLMNDNDDKRLVIERCAI 170

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
              +   P+ +WT +DIW YI   ++   PLY    +    R G +      +   +   
Sbjct: 171 RGRVVSNPIIDWTHKDIWDYIRSNHMPYNPLYDMGYK----RVGCVGCPMAGKNRYKEFA 226

Query: 238 VIKKRMVRF 246
              K    +
Sbjct: 227 DFPKYKAAY 235


>UniRef50_Q30U94 Phosphoadenylylsulfate reductase (Thioredoxin) n=4 Tax=Bacteria
           RepID=Q30U94_SULDN
          Length = 238

 Score =  136 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 48/294 (16%), Positives = 87/294 (29%), Gaps = 87/294 (29%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           ++I   +       +  ++     E  +   +  S G +  V+  +  K          +
Sbjct: 3   EKINFLNKEFKNVPTKELLEFFLKESKDSIALSSSFGAEDQVLSDMVLKIESETN----I 58

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAM---------GINPFVHGSAKHT 111
             +DTG    E Y+   RT   Y  ++ V+                 G    V    +  
Sbjct: 59  FTLDTGRLPYETYDVMQRTNLKYNTKIKVYFPNSEDIEKLYQQQGINGFYDSVENRKECC 118

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
              K   LK+AL   G D    G R  +  +R   +++ + +                  
Sbjct: 119 YARKIAPLKRAL--MGIDIWITGLRAQQSLTRKSTQLFEWDEENR--------------- 161

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                    I++ PL  W+E+D+W+YI   ++    L+ +                    
Sbjct: 162 --------VIKLNPLILWSEEDVWRYINENSVPYNALHDSG------------------- 194

Query: 232 DLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                         + ++GC P T AVE                 T  R GR  
Sbjct: 195 --------------YPSIGCAPCTRAVE---------------EGTDIRSGRWW 219


>UniRef50_A6WVB8 Phosphoadenosine phosphosulfate reductase n=2 Tax=Ochrobactrum
           RepID=A6WVB8_OCHA4
          Length = 249

 Score =  136 bits (341), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 46/276 (16%), Positives = 82/276 (29%), Gaps = 86/276 (31%)

Query: 21  REVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTA 80
           RE+        ++ S G +S+V+LH+  +         P+L +DTG  FR   ++R    
Sbjct: 34  RELYE--GQIAVVSSFGAESAVLLHMISEI----DPATPVLFLDTGKHFRATLDYRHDLV 87

Query: 81  KAYGC-ELLVHKNPEGVAMGINPFV----HGSAKHTDIMKTEGLKQALNKYGFDAAFGGA 135
              G  ++      E      +PF         +   I K E + +A+  Y   A   G 
Sbjct: 88  DRLGLTDVQDILPLEDSLKADDPFGALSMTDKDRCCFIRKVEPMARAVAPY--RAWMTGR 145

Query: 136 RRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIW 195
           ++ +  +R    ++                          + G  IR+ PL+     D+ 
Sbjct: 146 KQFQASTRESLPVFE-------------------------SVGSRIRINPLARLQAADLK 180

Query: 196 QYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLT 255
            Y    ++   PL                                      R++GC P T
Sbjct: 181 AYAEKHDLPPHPLIAQGY---------------------------------RSIGCMPCT 207

Query: 256 GAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
             V                    +R GR    ++  
Sbjct: 208 RPVS---------------EGEDQRAGRWAGSEKTE 228


>UniRef50_Q5KLW1 Phosphoadenylyl-sulfate reductase (Thioredoxin), putative n=4
           Tax=Basidiomycota RepID=Q5KLW1_CRYNE
          Length = 272

 Score =  135 bits (340), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 39/242 (16%), Positives = 71/242 (29%), Gaps = 39/242 (16%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAF--YPGTLPFPLLHVDTGWKFRE 71
                I+              + G   +  + +  K       T   PL+ +DT   F E
Sbjct: 26  KTPQEILTWAVDNVDGLYQTTAFGLTGTAAVDMISKISLDREETHLVPLIFLDTLHHFPE 85

Query: 72  MYEFRDRTAKAYGCELLVHKNP-------EGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
                   A  Y   L ++  P         V  G   +      +  ++K E   +A  
Sbjct: 86  TLALAQTMADTYLAPLHIYTPPGVSTAEEFAVKYGEKLWETDEGAYDYLVKVEPAARAYK 145

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           + G  A   G RR +   RA  ++    +R                          +++ 
Sbjct: 146 ELGVRAVITGRRRSQGADRADLKVLEIDER------------------------GLLKIN 181

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL  W+ +++ +YI  E +   PL     R + +             D        +R  
Sbjct: 182 PLIGWSFKEVKEYIDKEGVPYNPLLDKGYRSIGDVHSTAP------PDPNAASDAAERSG 235

Query: 245 RF 246
           R+
Sbjct: 236 RW 237


>UniRef50_Q3A3P4 Phosphoadenylylsulfate reductase (Thioredoxin) n=5 Tax=cellular
           organisms RepID=Q3A3P4_PELCD
          Length = 236

 Score =  135 bits (339), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 47/280 (16%), Positives = 80/280 (28%), Gaps = 86/280 (30%)

Query: 16  SIHIIREVA-AEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           +  IIR    A      M  S   +  V++ +  K          +  +DTG    E Y+
Sbjct: 20  AEDIIRAGIRAAGGEVSMASSFSVEDVVVIDMLHKIA----PQVRVFAIDTGRLNEETYQ 75

Query: 75  FRDRTAKAYGCELLVHKNP----EGVAMGINPFV-----HGSAKHTDIMKTEGLKQALNK 125
             +     Y   +  +       E +      F          +   I K E L +AL+ 
Sbjct: 76  VAESVRARYDLRIDWYFPERQTVENLEREKGLFSFRESLDNRHECCRIRKVEPLGRALD- 134

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
            G      G RR +  +RA+       +                        G  +++ P
Sbjct: 135 -GLSGWVVGLRRQQSVTRAQLSPLEIDEAH----------------------GGIVKISP 171

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           L++W+E+ +W Y     + I  L+                                    
Sbjct: 172 LADWSEEQVWAYAEKHALPIHRLHRMG--------------------------------- 198

Query: 246 FRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
           + ++GC P T AVE               +    R GR  
Sbjct: 199 YPSIGCAPCTRAVE---------------AGEDLRAGRWW 223


>UniRef50_B1L7P4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Korarchaeum cryptofilum OPF8 RepID=B1L7P4_KORCO
          Length = 536

 Score =  135 bits (339), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 48/241 (19%), Positives = 77/241 (31%), Gaps = 45/241 (18%)

Query: 12  LEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
            E ESI +I     +    ++ +S GKDSSV+L LAR+      + F     DTG +  E
Sbjct: 185 KEFESIRMI-WRLTKGKRAIVSFSGGKDSSVLLELARR----SDINFLTYFNDTGLELPE 239

Query: 72  MYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEGLKQALNKYGF 128
              F + T        ++    +     +    P          ++K     +AL     
Sbjct: 240 TISFVESTGCD-----IIGDAGDSFWRSLDRFGPPARDYRWCCKVIKLMPTYRALKHLRP 294

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
                G RR E  +R +                                   +   PL++
Sbjct: 295 GLTLVGQRRYESSARMRSPYM----------------------WRNDWLPGFLTAAPLND 332

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           W+    W YI + N+ + PLY        ER G  +       D            R+ +
Sbjct: 333 WSNLQTWLYIRVRNLRVNPLYFEG----FERLGCYLCPASRLSDYMRLRE------RYSS 382

Query: 249 L 249
           L
Sbjct: 383 L 383


>UniRef50_C5TAI7 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=1 Tax=Acidovorax
           delafieldii 2AN RepID=C5TAI7_ACIDE
          Length = 283

 Score =  135 bits (339), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 52/294 (17%), Positives = 87/294 (29%), Gaps = 85/294 (28%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           ++    +      AE+  ++R+ AA         S+G +  V+ HL         L  P+
Sbjct: 20  LNARASSDFAAKLAETQALLRQAAALGE-VTQASSLGAEDVVITHLVNALA----LDIPV 74

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV------AMGINPFVHG---SAKHT 111
             ++TG    E     +RT       + V++             G +             
Sbjct: 75  FVLETGALHTETLALLERTQAHSRAPVQVYRPQHEAVIHFIREHGQDAMYRSIELRKACC 134

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
            I K E L +AL   G      G RR++  +RA+  +                       
Sbjct: 135 QIRKMEPLARALA--GKKGWITGLRREQSNARAEVPLVD--------------------- 171

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
             ++      +  PL+NWT  D+W YI  + +D  PL+                      
Sbjct: 172 TSEVAAKGLTKFNPLANWTWGDVWHYIATQGVDYNPLHDQF------------------- 212

Query: 232 DLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                         + ++GC P T AV                     R GR  
Sbjct: 213 --------------YPSIGCAPCTRAV---------------TLGEDFRSGRWW 237


>UniRef50_Q8IR76 CG4407, isoform B n=8 Tax=Drosophila RepID=Q8IR76_DROME
          Length = 294

 Score =  134 bits (338), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 51/290 (17%), Positives = 87/290 (30%), Gaps = 64/290 (22%)

Query: 1   MDQIRLTHL--RQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTL 56
           M+      L   + + ++     E    +     +  ++ GKD +V+L L  +      +
Sbjct: 58  MELTAEDRLAIEERQNKAFAFFAETLQIYGVEELIFCFNGGKDCTVLLDLLMRYLRQENI 117

Query: 57  ---PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDI 113
                P+L++ +G  F E+ EF +R  + Y  +L+ ++                      
Sbjct: 118 SSGDIPMLYIKSGDSFPEIDEFVERCVRNYRVQLVQYEGT-------------------- 157

Query: 114 MKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
                LK+AL     D             R K      R+             L      
Sbjct: 158 -----LKEALTHMSSD-----------MPRIKAVFVGSRNTD------PYCQHLAPMQPT 195

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
             +    +R+ PL  W+  D+W YI L ++    LY      +  R   +      R D 
Sbjct: 196 DNDWPPMMRLNPLLEWSYHDVWHYIHLNSVPYCSLYDRGYTSIGNRANTVPNPHLRRTDA 255

Query: 234 QPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
           +         V    LG                      L   T ER GR
Sbjct: 256 ECECGSNSDAVCSCDLG---------------GYRPAWELQDATMERAGR 290


>UniRef50_Q4JBE9 Conserved Archaeal protein n=1 Tax=Sulfolobus acidocaldarius
           RepID=Q4JBE9_SULAC
          Length = 308

 Score =  134 bits (337), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 54/305 (17%), Positives = 98/305 (32%), Gaps = 46/305 (15%)

Query: 9   LRQLEAESIHIIREVAAEFSNP--VMLYSIGKDSSVMLHLARKAFYPGT--LPFPLLHVD 64
           +     E+I +I   + E SN    + +S GKDS+ +L L  KA   G       +++ D
Sbjct: 1   METRVEEAIELIINASEELSNLPWELGFSGGKDSTTVLSLTLKAMERGAMIKTLYVVYAD 60

Query: 65  TGWKFR----EMYEFRDRTAKAYGCELLVHKNPEGV-----AMGINPFVHGSAKHTDIMK 115
           T  +      E  +  +        + +     E         G     H      + +K
Sbjct: 61  TLLEHPILRKEALDALESLKVYPNVKPIRLTPIEDFISMMVERGYPAPSHRFRWCMERLK 120

Query: 116 TEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQI 175
              +K+ + + G      G R  E   RAK                      ++  + +I
Sbjct: 121 LRPMKRFMEQLGKFVQLSGVRMTESSERAK-------------------QTAYNGKHEKI 161

Query: 176 NKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
            +  +  + P+ +WT +D+++Y+  E            R        L+ + + + D   
Sbjct: 162 IRLGNPIIMPILDWTTEDVFRYLRSER-----------RWDGREFDYLLNLYEVKEDNDG 210

Query: 236 GEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMEL 295
                   VRF   GCW  T            + E   +     R  R    D+ G    
Sbjct: 211 CGCALTTDVRF---GCWVCTVVKNDKMPVSDTLKEARKMIMDISRDLRYRIIDKNGKPRS 267

Query: 296 KKRQG 300
              +G
Sbjct: 268 LNEEG 272


>UniRef50_UPI000186D96A molybdopterin- binding protein, putative n=1 Tax=Pediculus humanus
           corporis RepID=UPI000186D96A
          Length = 501

 Score =  134 bits (337), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 37/233 (15%), Positives = 70/233 (30%), Gaps = 46/233 (19%)

Query: 11  QLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL--LHVDTG 66
            L   S+ +I     ++      + ++ GKD +V+LHL           F +  +++  G
Sbjct: 296 NLVRNSLKVIETAFEKYKSDEIYLSFNGGKDCTVLLHLIWTVCKIQNYTFKINCVYIKNG 355

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
             F E+ +F   T   Y   +++   P   A+            T++ K           
Sbjct: 356 SVFPEVDKFVTDTVNKYKLNVVIAFGPIKEAL------------TELHKRIP-------- 395

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
              A F G RR +  S                        L        +    +RV P+
Sbjct: 396 EIKAIFMGTRRTDPHS----------------------ENLQEFQECDKDWPPLMRVSPI 433

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
            +W+  DIW ++ +  +    LY      +                 +     
Sbjct: 434 LDWSYHDIWDFLRILPVPYCTLYNEGYTSIGNSKNTQPNPSLKIPGYENKYHP 486


>UniRef50_Q9VYI5 CG4407, isoform A n=4 Tax=melanogaster subgroup RepID=Q9VYI5_DROME
          Length = 322

 Score =  134 bits (337), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 51/290 (17%), Positives = 87/290 (30%), Gaps = 64/290 (22%)

Query: 1   MDQIRLTHL--RQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTL 56
           M+      L   + + ++     E    +     +  ++ GKD +V+L L  +      +
Sbjct: 86  MELTAEDRLAIEERQNKAFAFFAETLQIYGVEELIFCFNGGKDCTVLLDLLMRYLRQENI 145

Query: 57  ---PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDI 113
                P+L++ +G  F E+ EF +R  + Y  +L+ ++                      
Sbjct: 146 SSGDIPMLYIKSGDSFPEIDEFVERCVRNYRVQLVQYEGT-------------------- 185

Query: 114 MKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
                LK+AL     D             R K      R+             L      
Sbjct: 186 -----LKEALTHMSSD-----------MPRIKAVFVGSRNTD------PYCQHLAPMQPT 223

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
             +    +R+ PL  W+  D+W YI L ++    LY      +  R   +      R D 
Sbjct: 224 DNDWPPMMRLNPLLEWSYHDVWHYIHLNSVPYCSLYDRGYTSIGNRANTVPNPHLRRTDA 283

Query: 234 QPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
           +         V    LG                      L   T ER GR
Sbjct: 284 ECECGSNSDAVCSCDLG---------------GYRPAWELQDATMERAGR 318


>UniRef50_C1XVG3 Phosphoadenylylsulfate reductase (Thioredoxin) n=3 Tax=Deinococci
           RepID=C1XVG3_9DEIN
          Length = 222

 Score =  134 bits (336), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 53/281 (18%), Positives = 87/281 (30%), Gaps = 80/281 (28%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           E +   +IR    E+ + +M  +   +  V++ LA +A Y G     ++ VDTG+ F E 
Sbjct: 10  ETDPRVVIRWAMEEYPDSLMTSAFNLNGVVLIDLAAQAGYTG----EVVFVDTGYHFPET 65

Query: 73  YEFRDRTAKAY-GCELLVHKNPEGVA-MGINPFVHGSAKHTDIMKTEGLKQALNKYGFDA 130
            + R+R A  Y     +           G   +           K   L++ L +    A
Sbjct: 66  LQTRERLAARYSQMRFVTLSAGLAPEPWGEERYRSDPDGCCAARKVAPLREYLARKNPSA 125

Query: 131 AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWT 190
                 RD+  +RA                                 GE +RV PL+ WT
Sbjct: 126 LLNARSRDQAATRAGLGFLEP--------------------------GERLRVNPLAYWT 159

Query: 191 EQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLG 250
            + +  Y    ++ + PLY +                                  F ++G
Sbjct: 160 REQLEAYARTRDLPVNPLYWSG---------------------------------FLSIG 186

Query: 251 CWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           CWP T AV                     R GR   + +  
Sbjct: 187 CWPCTRAVRP---------------GEEARAGRWEGQGKTE 212


>UniRef50_A1SNA9 Phosphoadenylylsulfate reductase (Thioredoxin) n=3 Tax=Bacteria
           RepID=A1SNA9_NOCSJ
          Length = 282

 Score =  134 bits (336), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 51/283 (18%), Positives = 80/283 (28%), Gaps = 87/283 (30%)

Query: 14  AESIHIIREVAAE-FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
            E   +I     E      ++ ++  D  V+L +A +          ++ VDTG      
Sbjct: 42  QEPEDVIAWALEELGDRIAIVTALQVDGMVVLDMATRL----RPDIRVVTVDTGRLPDAT 97

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVA-------MGINPFVH---GSAKHTDIMKTEGLKQA 122
             F D     Y        +P+           G++ F        +   + K   L QA
Sbjct: 98  LRFIDEARAHYPRTRWDVLHPDAAEVQAMVAERGVDLFRSSVADRMRCCQVRKVRPLTQA 157

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           L   G D  F G RRD+  SRA  +                            + G  ++
Sbjct: 158 LR--GLDGWFTGLRRDQWASRAAIKKVELD----------------------HDHGGIVK 193

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           V  L++W   D+W Y+    + + PLY                                 
Sbjct: 194 VNALADWASADVWGYVEEHGVPVHPLYAQGYT---------------------------- 225

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                +LGC P T  V                    +R GR  
Sbjct: 226 -----SLGCGPCTRPVA---------------VGEDDRAGRWW 248


>UniRef50_Q0BUS4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Granulibacter
           bethesdensis CGDNIH1 RepID=Q0BUS4_GRABC
          Length = 249

 Score =  133 bits (335), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 46/280 (16%), Positives = 84/280 (30%), Gaps = 86/280 (30%)

Query: 19  IIREVA-AEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFR 76
           ++R+    EF     ++ S G +S+++L L  +         P++ ++T   F E   +R
Sbjct: 41  LLRQAIMEEFAGRIAVVSSFGAESALLLALVAEI----DPATPIVFLETERHFPETLAYR 96

Query: 77  DRTAKAYGCELLVHKNPE-----GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAA 131
            + A   G   +   +P+             +   +     + K   L++AL+  GFDA 
Sbjct: 97  QQLANLLGLTGIRDIHPDPEEAAAQDPDAELWYFDADACCALRKVRPLEKALS--GFDAW 154

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
             G +R +  +RA                                +G+  +  PL++W  
Sbjct: 155 ISGRKRHQASTRAALPFREV-------------------------EGKFTKFNPLADWGA 189

Query: 192 QDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGC 251
            DI   +    +   PL                                       ++GC
Sbjct: 190 ADIEAEMTRRQLPRHPLVAKGY---------------------------------PSIGC 216

Query: 252 WPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
            P T  V   A                 R GR   R +  
Sbjct: 217 APCTQPVAPGADP---------------RSGRWRGRAKTE 241


>UniRef50_C2HVQ6 Putative uncharacterized protein n=1 Tax=Vibrio cholerae bv.
           albensis VL426 RepID=C2HVQ6_VIBCH
          Length = 661

 Score =  133 bits (335), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 46/303 (15%), Positives = 83/303 (27%), Gaps = 49/303 (16%)

Query: 14  AESIHII----REVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGT------LPFPLLH 62
            E+I  +    +E+  +     V+ YS GKDS+ +L +   A            P  ++ 
Sbjct: 27  KETIQRLVTKTKELYQKDDIPWVIGYSGGKDSTAILQIVWNAVAELKKEGKATKPVHVIS 86

Query: 63  VDTGWKFREMYEFRDRTAKAY-------GCELLVHKNPEG---------VAMGINPFVHG 106
            DT  +   +  + DR+ K            +  H+             +  G     + 
Sbjct: 87  TDTLVENPIVALWVDRSLKQMKKAVDEQNLPIQPHRLTPKTEDRFWVNLIGKGYPAPRYK 146

Query: 107 SAKHTDIMKTEG----LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
               TD +K       ++  + K G      G R+ E   RA              + ++
Sbjct: 147 FRWCTDRLKISPSNSFIQNVVKKNGEAILVLGTRKHESTVRA--------ASMENIENRS 198

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
                    N            P+ +WT  D+W ++  +            R        
Sbjct: 199 DNTRKNDGLNVNTQLDRVWVYTPIEDWTNDDVWSFLTQQKNPW------GYRNTDLLGMY 252

Query: 223 LMMID-DNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQ 281
               D      +           RF   GC+  T   E  +       +E          
Sbjct: 253 QGATDGGECPLVVDKSTPSCGDSRF---GCYVCTMVGEDKSMAAMIANDEEKEWMLPLLA 309

Query: 282 GRV 284
            R 
Sbjct: 310 LRN 312


>UniRef50_C6Y361 Phosphoadenosine phosphosulfate reductase n=2 Tax=Bacteria
           RepID=C6Y361_PEDHD
          Length = 234

 Score =  133 bits (335), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 50/288 (17%), Positives = 84/288 (29%), Gaps = 87/288 (30%)

Query: 15  ESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           + +  +R   AE+    V   S G +  V+ H+         LP  +  ++TG  F E Y
Sbjct: 16  DPVEALRFFTAEYPGKIVFSTSFGWEDQVITHMIFA----NDLPIEVFTLETGRLFPETY 71

Query: 74  EFRDRTAKAYGCELLVHKNPEGVAMGI---------NPFVHGSAKHTDIMKTEGLKQALN 124
              +RT + Y   +  +         +            V    +   I K E L++AL 
Sbjct: 72  YVWNRTLEIYKKPIHAYFPQAEALQEMVDKKGPSSFYESVENRKECCGIRKLEPLRRALK 131

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             G D    G R ++  +R       + ++                          I+  
Sbjct: 132 --GNDLWVTGIRSEQSLNRHDMANLEWDEQNQ-----------------------LIKFH 166

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P+  W+  ++ +YI   NI    L+                                   
Sbjct: 167 PIFFWSLAEVKEYIKKNNIVYNTLHDKG-------------------------------- 194

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGS 292
            F ++GC P T AV                     R GR    DQ+  
Sbjct: 195 -FPSIGCAPCTRAVR---------------EGEDFRAGRWWWEDQSKK 226


>UniRef50_C4G023 Putative uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC
           49176 RepID=C4G023_ABIDE
          Length = 537

 Score =  133 bits (334), Expect = 7e-30,   Method: Composition-based stats.
 Identities = 53/326 (16%), Positives = 100/326 (30%), Gaps = 53/326 (16%)

Query: 10  RQLEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLP-----FPLLHV 63
           +         IR +        V+ YS GKDS+  L L   A              +++ 
Sbjct: 9   KDKIEGLKDTIRNLYLADDIPWVIGYSGGKDSTATLQLVWYALRELPAEKLTKVVHVINT 68

Query: 64  DTGWKFREMYEFRDRTAKAYG-----CE------LLVHKNPEGVA---------MGINPF 103
           DT  +   + ++ +++ K                 + H+    V           G    
Sbjct: 69  DTLVESPVIEKWVEKSLKMMDESSSKIPSKVNTLFVTHRLTPAVDNTYWVNFIGRGYPFP 128

Query: 104 VHGSAKHTDIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWD 159
                  TD +K + + + +     ++G      G R+ E  +RA  R  ++ ++    +
Sbjct: 129 RKKLRWCTDRLKIQPVNKFVKDKIAEHGEIILVLGTRKAESAARA--RTMTYYEKKRVRE 186

Query: 160 PKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLER 219
             +  P L +               PL +WT  D+W ++                  L+ 
Sbjct: 187 LLSPNPTLANEL----------VFSPLEDWTNNDVWVFLMQYENP-----WGLSNHELQT 231

Query: 220 DGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQT--LPEIIEEMLVSTT 277
             M    D     +           RF   GCW  T   +  +    +    E+  ++  
Sbjct: 232 LYMSATEDKECPMMTEKNQPTCGQSRF---GCWVCTMVEKDKSMEAMISNEDEKAWMTPL 288

Query: 278 SERQGRVIDRDQAGSMELKKRQ-GYF 302
            E + R  D D+       K+  GY 
Sbjct: 289 LEFRNRFGDEDKDRGRRSFKKMQGYL 314


>UniRef50_A6GTB0 Phosphoadenosine phosphosulfate reductase n=3 Tax=Proteobacteria
           RepID=A6GTB0_9BURK
          Length = 265

 Score =  133 bits (333), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 45/284 (15%), Positives = 84/284 (29%), Gaps = 87/284 (30%)

Query: 15  ESIHII-REVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           +++ I+    A EF +  +  S+  + +V+  +  +      L   +  ++TG   ++  
Sbjct: 44  QALEILLNNAANEFDSIALASSLAAEDNVLFDVIARL----KLNIRVFSLNTGRLHQQTL 99

Query: 74  EFRDRTAKAYGCELLVHKNPEGVA------MGINPFVHG---SAKHTDIMKTEGLKQALN 124
           +        YG  +   +             G + F        +   I K E L +AL 
Sbjct: 100 DVAPALQAKYGQTVQWFEPQAKAVETYVNTKGRDAFYESTALRKECCSIRKVEPLARALQ 159

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             G  A   G R+ +  +RA   +  F                              +  
Sbjct: 160 --GAKAWVTGQRQAQAATRATLPVREFD-----------------------ADRGIEKFN 194

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           PL++W+E D+W YI   ++ +  L+                                   
Sbjct: 195 PLADWSEADVWTYIRQFDVPVNTLHFEG-------------------------------- 222

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRD 288
            F ++GC P T A+                     R GR    D
Sbjct: 223 -FPSIGCEPCTRAI---------------TIGEDIRAGRWWWED 250


>UniRef50_Q8UH67 Phosphoadenosine phosphosulfate reductase n=10 Tax=Rhizobiales
           RepID=CYSH_AGRT5
          Length = 260

 Score =  132 bits (332), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 50/276 (18%), Positives = 84/276 (30%), Gaps = 86/276 (31%)

Query: 19  IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDR 78
            +  VA      V   S+G +  V+      A     LP  ++ ++TG  F+E  +  D 
Sbjct: 34  RLSFVAGLGGRAVFTTSLGIEDQVIT----AAIGTHRLPIDVVTLETGRLFKETVDLIDE 89

Query: 79  TAKAYGCELLVHKNPE------GVAMGINPFVHG---SAKHTDIMKTEGLKQALNKYGFD 129
           T + +G E+   +  +          G+N F            + K   L +AL   G  
Sbjct: 90  TEERFGIEIRRFRPEQDDIDAYAAKYGLNGFYESVEARHACCHVRKLIPLGKALE--GAA 147

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
               G RR +  +RA      F                         +   I++  L++W
Sbjct: 148 FWITGLRRGQSGNRAATPFAEFD-----------------------AERNLIKINALADW 184

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
             + I  Y+  ENI + PL+                                    + ++
Sbjct: 185 DIEQIRAYVAEENIPVNPLHQRG---------------------------------YPSI 211

Query: 250 GCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
           GC P T A++                   ER GR  
Sbjct: 212 GCEPCTRAIKP---------------GEPERAGRWW 232


>UniRef50_A5PAV0 Phosphoadenosine phosphosulfate reductase n=1 Tax=Erythrobacter sp.
           SD-21 RepID=A5PAV0_9SPHN
          Length = 241

 Score =  132 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 46/288 (15%), Positives = 90/288 (31%), Gaps = 85/288 (29%)

Query: 11  QLEAESIHIIRE-VAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           + E +++  + E +  ++     M+ S G +S V+L +  +         P+L  +TG  
Sbjct: 16  EREGKTLAFLAESILRDYPGCVAMVSSFGAESIVLLDMVARI----NPNTPILLNETGML 71

Query: 69  FREMYEFRDRTAKAYGC-ELLVHKNPE----GVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
           F E  E++   +   G   + + +                 + S     + K+E L++AL
Sbjct: 72  FAETLEYQREVSALLGLTNVQLVRPTRQRLAEEDPNGLLHRNDSDACCSLRKSEPLRRAL 131

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
               FDA   G ++ +   RA+ +                                 +++
Sbjct: 132 AP--FDAWITGRKKFQNDKRAEMQPVEQDGA------------------------GRVKL 165

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL++WT  DI  Y    N+   PL                                   
Sbjct: 166 NPLADWTPSDIRDYFDRYNLPRHPLVSQG------------------------------- 194

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
             + ++GC P T  V               ++    R GR    ++  
Sbjct: 195 --YPSIGCAPCTSRV---------------LAGEDARAGRWRGTEKTE 225


>UniRef50_P18408 Phosphoadenosine phosphosulfate reductase n=50 Tax=Dikarya
           RepID=MET16_YEAST
          Length = 261

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 48/296 (16%), Positives = 83/296 (28%), Gaps = 84/296 (28%)

Query: 7   THLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
             L +LE     II      F +     + G    V + +  K      +P  LL +DT 
Sbjct: 22  EQLIKLE-TPQEIIAWSIVTFPHLFQTTAFGLTGLVTIDMLSKLSEKYYMP-ELLFIDTL 79

Query: 67  WKFREMYEFRDRTAKAY----GCELLVHKNP-------EGVAMGINPFVHGSAKHTDIMK 115
             F +    ++   K Y       + V+K              G   +     K+  + K
Sbjct: 80  HHFPQTLTLKNEIEKKYYQPKNQTIHVYKPDGCESEADFASKYGDFLWEKDDDKYDYLAK 139

Query: 116 TEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQI 175
            E   +A  +    A F G R+ +  +R++  I    +                      
Sbjct: 140 VEPAHRAYKELHISAVFTGRRKSQGSARSQLSIIEIDELNG------------------- 180

Query: 176 NKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
                +++ PL NWT + + QYI   N+    L                           
Sbjct: 181 ----ILKINPLINWTFEQVKQYIDANNVPYNELLDLGY---------------------- 214

Query: 236 GEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                      R++G +  T  V+                   ER GR   + +  
Sbjct: 215 -----------RSIGDYHSTQPVK---------------EGEDERAGRWKGKAKTE 244


>UniRef50_A1WQX9 Phosphoadenylylsulfate reductase (Thioredoxin) n=2
           Tax=Comamonadaceae RepID=A1WQX9_VEREI
          Length = 293

 Score =  131 bits (329), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 52/293 (17%), Positives = 85/293 (29%), Gaps = 70/293 (23%)

Query: 9   LRQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
                A++  ++R+ AA          S+G +  V+ HL         L  P+  ++TG 
Sbjct: 28  FDAKLAQTQALLRQAAALGADAVTQASSLGAEDVVITHLINAL----QLDIPIFVLETGA 83

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVA------MGINPFVHG---SAKHTDIMKTEG 118
              E     +RT       +  ++   G         G +              I K E 
Sbjct: 84  LHTETLALLERTQAGSRAPVTPYRPETGAVMHFIRSHGQDAMYRSMALRKSCCGIRKLEP 143

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L +AL   G  A   G RR++  +RA   +    +            +      G    G
Sbjct: 144 LARALA--GKSAWITGLRREQSGARADMPLIDLSEVAADGVDGADGADSAAGTAGAAGAG 201

Query: 179 E------SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
                    +  PL++WT  D+W YI    +D  PL+                       
Sbjct: 202 GHRGSAGLTKFIPLAHWTWGDLWHYIATHGVDYNPLHDRF-------------------- 241

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                        + ++GC P T A+                     R GR  
Sbjct: 242 -------------YPSIGCAPCTRAIS---------------LGEDLRSGRWW 266


>UniRef50_C7G6A6 Phosphoadenosine phosphosulfate reductase n=3 Tax=Clostridiales
           RepID=C7G6A6_9FIRM
          Length = 525

 Score =  131 bits (329), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 47/237 (19%), Positives = 82/237 (34%), Gaps = 39/237 (16%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           +        +  E+ + IR+   EF   +  + +S GKDS+V  +L  +A    T     
Sbjct: 91  EANKERYEYITQEAGNYIRKAVGEFGAMDMFVSFSGGKDSTVTSNLVLRAL--STPQIMH 148

Query: 61  LHVDTGWKFREMYEFRDRTAKAY-GCELLVHKNPE----GVAMGINPFVHGSAKHTDIMK 115
           +  DT  +F   Y + +R  K +    ++  +N E     +   I P          + K
Sbjct: 149 IFGDTTLEFPFTYTYVERFKKNHPKTPVISARNKEKDFEELCKLIGPPSRVMRWCCTVFK 208

Query: 116 TEGLKQALNKYGFD----AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
           T  +++ +     D      F G RR E  SR+K                      +   
Sbjct: 209 TGTIQKKIRSLYRDKKQILTFYGIRRSESVSRSK----------------------YERE 246

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
           +      +   + P+ +W + DIW YI    ID    Y         R G     ++
Sbjct: 247 SDSPKITKQRIISPIIDWMDFDIWLYILTTGIDFNDAYRLGYA----RVGCWCCPNN 299


>UniRef50_A3UHA4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Oceanicaulis
           alexandrii HTCC2633 RepID=A3UHA4_9RHOB
          Length = 249

 Score =  131 bits (328), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 46/266 (17%), Positives = 77/266 (28%), Gaps = 83/266 (31%)

Query: 31  VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGC-ELLV 89
            ++ S G +S+V+LHL  +A        P+L +DTG  F E   +RD  ++  G  ++  
Sbjct: 45  CVVSSYGAESAVILHLVAQA----KPDTPVLFMDTGQLFDETLAYRDALSERLGLTDVRT 100

Query: 90  HKNPEGVAMGINP----FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAK 145
            +         +P              I KT  L  AL  +       G +R     RA 
Sbjct: 101 LQPNPDHVKADDPDGVLHKTNPDLCCHIRKTLPLISALRPFK--VWISGRKRHHGGERAA 158

Query: 146 ERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDI 205
                 +D                           +++ PL +W+   I  Y    ++  
Sbjct: 159 LPRVEIQD-------------------------GKLKLNPLFDWSRDAINAYFETHDLPP 193

Query: 206 VPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTL 265
            P+                                       ++GC P T  V+      
Sbjct: 194 HPMVAEGY---------------------------------PSIGCLPCTSQVKDP---- 216

Query: 266 PEIIEEMLVSTTSERQGRVIDRDQAG 291
                     T   R GR   +D+  
Sbjct: 217 ----------TDDPRAGRWAGQDKTE 232


>UniRef50_B3RLV6 Putative uncharacterized protein (Fragment) n=1 Tax=Trichoplax
           adhaerens RepID=B3RLV6_TRIAD
          Length = 485

 Score =  131 bits (328), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 45/280 (16%), Positives = 84/280 (30%), Gaps = 58/280 (20%)

Query: 11  QLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHL----ARKAFYPGTLPFPLLHVD 64
           +   E+  I+     ++   N  + ++ GKD +V+LH+     +  F         ++  
Sbjct: 258 KRIQEAFQIVDRALEQYGLNNIAIAFNGGKDCTVILHIFYCFVKSRFPEQIPKIKAIYTK 317

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALN 124
           +   F EM +F  +    Y  ++    +                     MK+   + ++ 
Sbjct: 318 SEDIFTEMDQFVSKCVDRYNLDITTISSD--------------------MKSALEEYSIR 357

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
           +    A   G RR +  S                                 +  E +RV 
Sbjct: 358 EPTVKAVIMGTRRADPYSNQLTPFC----------------------MTDGDWPEYLRVH 395

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P+ +W+  +IWQ++   +I    LY      +             R   +    IK+   
Sbjct: 396 PILDWSYSEIWQFLRHSSIPYCSLYDLGYTSLGGIHNTKPNSSLRRTRDEIETFIKEG-- 453

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRV 284
              TL   PL             +    L     ER GR 
Sbjct: 454 ---TLEAEPLL-----QFDGYYYLPAYFLTEEQLERAGRS 485


>UniRef50_UPI000169461E phosphoadenosine phosphosulfate reductase n=1 Tax=Paenibacillus
           larvae subsp. larvae BRL-230010 RepID=UPI000169461E
          Length = 179

 Score =  130 bits (327), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 44/236 (18%), Positives = 73/236 (30%), Gaps = 78/236 (33%)

Query: 56  LPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAM-----GINPFVHGSAKH 110
               + ++DT   F+E Y  +DR  + Y  E +  +    +A      G   +       
Sbjct: 4   PSIDIFYLDTHVHFKETYLTKDRLQEKYNIEFIQVEPKISLAEQADRFGEELWKSDPNSC 63

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
            +I K E L + L++Y  DA   G RRD+  +RA     ++  +F               
Sbjct: 64  CNIRKVEPLSRILSEY--DAWITGIRRDQAPTRANAPKAAYDTKF--------------- 106

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
                   +  +  PL+NWT  D+W YI    +   PL+                     
Sbjct: 107 --------DLAKFNPLANWTSDDVWDYIREYELIYNPLHDQ------------------- 139

Query: 231 IDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVID 286
                          + ++GC   T  V               +     R GR   
Sbjct: 140 --------------NYPSIGCEYCTRQV---------------LPGEDLRAGRWSG 166


>UniRef50_A5INH9 Phosphoadenosine phosphosulfate reductase n=2 Tax=Thermotogaceae
           RepID=A5INH9_THEP1
          Length = 723

 Score =  130 bits (326), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 41/236 (17%), Positives = 70/236 (29%), Gaps = 30/236 (12%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFSNP----VMLYSIGKDSSVMLHLARKAFYPGTLPF 58
           +     L  LE E++  I      +        + YS GKDS V+L L  +         
Sbjct: 104 EKNKEALFVLENEALDFIEHTYKVYKKKGYLFAVSYSGGKDSQVVLDLVTRVVPCD--DL 161

Query: 59  PLLHVDTGWKFREMYEFRDRTAKAY-----GCELLVHKNP---EGVAMGINPFVHGSAKH 110
            ++  DT  +    YE  ++T + Y     G +  V K P           P        
Sbjct: 162 VVIFSDTTMEIPYTYENVEKTKEEYEKRYPGLKFYVAKPPKPMMEFWKEFGPPSRVHRWC 221

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
             + KT    + +          G    E            R          QR  +   
Sbjct: 222 CTVAKTAPFIRIIKA------IFGKTAGENSKTKLIVFDGIRSEESARRSNYQRLGIEAK 275

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI 226
           +  QI          + +W   +++ Y++  N+ +        R  L R G  +  
Sbjct: 276 HILQI------NAEVIRDWNTLEVFLYLYYRNLRMN----KGYRYGLNRVGCSVCP 321


>UniRef50_A5E7W2 Phosphoadenosine phosphosulfate reductase n=3
           Tax=Saccharomycetaceae RepID=A5E7W2_LODEL
          Length = 296

 Score =  130 bits (326), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 45/302 (14%), Positives = 81/302 (26%), Gaps = 87/302 (28%)

Query: 3   QIRLTHLRQL-----EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLP 57
            +   H+  L     E     +IR     F N     + G     +  +  K      + 
Sbjct: 8   NLTDEHIDFLNKRLIELSPQDLIRWAYYTFPNLYQTTAFGLTGLAISDMISKI---PNVK 64

Query: 58  FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV--------AMGINPFVHGSAK 109
             L+ +DT + F + YE  DR  + Y    +    P G+          G   +      
Sbjct: 65  IDLIFLDTLYHFPQTYELLDRVQQKYPDSKINVFKPRGINTEEEFVKKYGDELWEKDDTY 124

Query: 110 HTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWH 169
           +  ++K E  ++A      +    G R+ +  +R+   I    +                
Sbjct: 125 YDYLVKVEPSQRAYKTLNANVVLTGRRKSQGGARSSLPILEKDEVN-------------- 170

Query: 170 NYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDN 229
                      +++ PL NW    +  YI   N+    L     +               
Sbjct: 171 ---------NILKINPLWNWDFNQVKSYIDENNVPFNELLNLGYK--------------- 206

Query: 230 RIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQ 289
                             ++G W  T  V                    ER GR  D+ +
Sbjct: 207 ------------------SVGDWHSTVPVAD---------------GEDERAGRWKDKVK 233

Query: 290 AG 291
             
Sbjct: 234 TE 235


>UniRef50_Q11AI4 Phosphoadenosine phosphosulfate reductase n=5 Tax=cellular
           organisms RepID=Q11AI4_MESSB
          Length = 495

 Score =  130 bits (326), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 50/319 (15%), Positives = 86/319 (26%), Gaps = 52/319 (16%)

Query: 12  LEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAF-----YPGTLPFPLLHVDTG 66
           +E+    I     ++    V+ YS GKDS+  L L   A         T P  ++  DT 
Sbjct: 12  VESRLREIREVYLSDNRPWVIGYSGGKDSTCALQLVWTALLGLPAEHRTKPVYVITSDTL 71

Query: 67  WKFREMYEFRDRTAKAY-------GCELLVHKNPEGVA---------MGINPFVHGSAKH 110
            +   +  + D T           G  +   K    V           G           
Sbjct: 72  VETPVIVRYIDVTLARIAAAAAEQGLPIKTEKVTPNVDRSFWVNLIGRGYPAPSRRFRWC 131

Query: 111 TDIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPE 166
           T+ +K E     +     ++G      G R  E  +RA+  + SF         ++   +
Sbjct: 132 TERLKIEPANDFIKARVAEFGEVVMVLGVRSSESATRAQ--VMSFHRIKGSVLSRHSSLQ 189

Query: 167 LWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI 226
               Y             P+  ++  D+W Y+                            
Sbjct: 190 NAFVYG------------PIEAFSTDDVWTYLLQSPSPW------GNNNRDLVAMYRNAQ 231

Query: 227 DDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE-RQGRVI 285
                 +           RF   GCW  T      +        E  +    E R     
Sbjct: 232 AGECPLVVDTTTPSCGNSRF---GCWVCTVVERDRSMEAMIDSGEDWLEPLLEFRDLLAE 288

Query: 286 DR---DQAGSMELKKRQGY 301
            +    +    E ++R G+
Sbjct: 289 TQTPEKKRLYREFRRRNGH 307


>UniRef50_UPI0001C3554A hypothetical protein ChatD1_24037 n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C3554A
          Length = 293

 Score =  129 bits (325), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 48/253 (18%), Positives = 84/253 (33%), Gaps = 25/253 (9%)

Query: 1   MDQIRL-THLRQLEAESIHIIRE---VAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPG 54
           M+Q RL          +I + +     A  +      + +S GKDS V+  LA+ A    
Sbjct: 1   MEQYRLFDDFSDKVKRAIQLFQMFEDAAVRYHKDGYYLAFSGGKDSVVLYVLAKMA---- 56

Query: 55  TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIM 114
            + F   +  T     E+  F          E       + +     P +  +    +++
Sbjct: 57  HVKFQAHYHLTTVDPPELVWFIREAFPDVKVEYPELTMWDLIVKKQMPPLRTARYCCEVL 116

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K  G + A           G R +E + RA         +           E        
Sbjct: 117 KEGGGEGAF-------TVTGVRWEESRKRANRDFLEIHKKKGAIYLNCDNEEDRRKLEIC 169

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
             KG+ I + P+ +WTE+DIW +I    +    LY         R G +         ++
Sbjct: 170 SLKGKRI-LNPIIDWTEEDIWYFIRKYQVPYCCLYDQG----FCRIGCIGCP---LASIR 221

Query: 235 PGEVIKKRMVRFR 247
             E   +R  ++R
Sbjct: 222 SREREFERYPKYR 234


>UniRef50_Q7M9C9 APS REDUCTASE n=1 Tax=Wolinella succinogenes RepID=Q7M9C9_WOLSU
          Length = 227

 Score =  129 bits (325), Expect = 9e-29,   Method: Composition-based stats.
 Identities = 45/280 (16%), Positives = 87/280 (31%), Gaps = 85/280 (30%)

Query: 15  ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
            +   +  +        + +S   +  V+L L  K        F +  ++TG  F +   
Sbjct: 4   ATKESLERLCEVKGLITLAFSHQAEDVVVLDLLLK---HYPRSFEVFTLETGKLFTQTLA 60

Query: 75  FRDRTAKAYGCELLVHKNPEGVA---------MGINPFVHGSAKHTDIMKTEGLKQALNK 125
           F +   + +   +  +                 G+   +    +   + K E LK+AL  
Sbjct: 61  FHEEVERFFNLTIQKYHPSPKALLELERELGEWGMRESLENRHRCCRVRKIEPLKEALK- 119

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
            G  A   G R ++  +RA+ +   F + F                       + ++  P
Sbjct: 120 -GKSAWVTGLRAEQSITRAELKSVEFDETF-----------------------DLLKFNP 155

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           LS W+E ++++YI    + + PLY                                    
Sbjct: 156 LSTWSETEVFEYIKEHALPLHPLYTEG--------------------------------- 182

Query: 246 FRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
           +R++GC P T A+E               +    R GR  
Sbjct: 183 YRSIGCSPCTRAIE---------------AGEELRAGRWW 207


>UniRef50_A9KBQ9 Phosphoadenosine phosphosulfate reductase n=3 Tax=Coxiella burnetii
           RepID=A9KBQ9_COXBN
          Length = 218

 Score =  129 bits (325), Expect = 9e-29,   Method: Composition-based stats.
 Identities = 41/236 (17%), Positives = 78/236 (33%), Gaps = 39/236 (16%)

Query: 12  LEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKF 69
              ++  +IR+   EF      +L S GKDS V+LHL R+          +  + +  +F
Sbjct: 9   KIKQAKALIRDTLNEFENKRVGLLCSFGKDSMVLLHLCREI----DPNIKVYSLVSDTEF 64

Query: 70  REMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
            E Y++     + +      +             +       +  K   ++  L +   D
Sbjct: 65  DETYQYIRFIVETWNLNYHQY------DFMQKDLIDSPGNCCNGRKVSAMQSVLAEL--D 116

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
               G R DE   R                          N+  +      +++ P+  +
Sbjct: 117 CWIAGVRGDEGTER-------------------------KNFAQREQVSNLVKINPILAF 151

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVR 245
           +E DIW+Y+ + NI + PLY    R +  R         ++ +         R   
Sbjct: 152 SEADIWRYLAINNISVHPLYSKGYRSLGCRLCSTPERGSDQSERDGRWRGTSRQGG 207


>UniRef50_B5Y6E1 Phosphoadenosine phosphosulfate reductase family protein n=1
           Tax=Coprothermobacter proteolyticus DSM 5265
           RepID=B5Y6E1_COPPD
          Length = 793

 Score =  129 bits (325), Expect = 9e-29,   Method: Composition-based stats.
 Identities = 39/244 (15%), Positives = 74/244 (30%), Gaps = 46/244 (18%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPV----MLYSIGKDSSVMLHLARKAFYPGTL 56
           M +     L  LE E+I  +  +   +   V    + +S GKDS V+L +  K   P   
Sbjct: 101 MLEKNKEQLEVLENEAIDFVNHIYKRYKGKVSAFVVSFSAGKDSQVILDIVSKVIPPE-- 158

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYG-----CELLVHK---NPEGVAMGINPFVHGSA 108
            + ++  DT  +    YE  + T + Y       +    +     E       P      
Sbjct: 159 DYFVIFTDTTMEIPPTYEAFEETKRKYRETYPELKFYTARNWKPAEATWKEFGPPSRLLR 218

Query: 109 KHTDIMKTEGLKQALNK------YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
               + K+  + + + +            F G R +E   R                   
Sbjct: 219 WCCSVHKSAPMIRLVREIVGRNDGVRIVVFDGVREEESTRR------------------- 259

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
              + +      +     I    +  WT  +++ YI    + +   Y       L+R G 
Sbjct: 260 ---KGYSRLAENVKHFTQINAEVIKRWTTTEVYTYILARELPLNTAYRLG----LDRVGC 312

Query: 223 LMMI 226
            +  
Sbjct: 313 SVCP 316


>UniRef50_A6L476 Putative sulfate adenylate transferase, subunit 2 n=4
           Tax=Bacteroides RepID=A6L476_BACV8
          Length = 289

 Score =  129 bits (325), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 37/232 (15%), Positives = 70/232 (30%), Gaps = 13/232 (5%)

Query: 29  NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELL 88
             ++ +S GKDS   L  A K +  G      +  DTGW+  + Y+      K  G  + 
Sbjct: 2   KIIVSFSGGKDSQACLIQAAKQY--GADKIEAVFCDTGWEHPDTYQHITDVCKQMGVRIT 59

Query: 89  VHKNPE---GVAMGINPFVHGSAKHTDI-MKTEGLKQALNKYGFDAAFG-GARRDEEKSR 143
             K       +      F     +   + +K + +   +           G R  E   R
Sbjct: 60  TLKPEFNFIEICKKYRRFPDPIRRFCTVDLKVKPMVDYILSLQESCIIIEGIRASESYKR 119

Query: 144 AKE--RIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLE 201
           +        F+  F   +          +        ++  +  +  WT Q++   I   
Sbjct: 120 SSMEEECMYFKSYFTPNEKGKFASYRKKDVKEWCGMYDASVLRSVFRWTAQEVIDCILNA 179

Query: 202 NIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWP 253
                PLY         R G    +  N  +++     K+   R + +    
Sbjct: 180 GQKPNPLYSRG----FSRVGCFPCVMSNLQNIKMLLNDKEMCSRLKNVEDEV 227


>UniRef50_A9DP87 Putative uncharacterized protein n=1 Tax=Kordia algicida OT-1
           RepID=A9DP87_9FLAO
          Length = 445

 Score =  129 bits (325), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 46/329 (13%), Positives = 91/329 (27%), Gaps = 64/329 (19%)

Query: 14  AESIHIIREVAAEF------SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP-------- 59
            ++ +II E+  ++         ++ +S GKDS+VML L   +                 
Sbjct: 2   KKTNYIIEEIIDQYTIDDNNRPWIIGFSGGKDSTVMLTLVWLSLLKIKNDIDEKFLKREV 61

Query: 60  -LLHVDTGWKFRE-------MYEFRDRTAKAYGCELLVH----KNPEGVA-----MGINP 102
            ++  DT  +          + E     A  +   + V     +  +         G   
Sbjct: 62  WVVCNDTLVENPIITNYVNGILEKIKTAAVRHNLPIKVKKTIPRLEDSFWVNLIGKGYPA 121

Query: 103 FVHGSAKHTDIMKTEGLKQALN--------KYGFDAAFGGARRDEEKSRAKERIYSFRDR 154
             +     T+ +K +   + ++        ++       G R+ E  SRAK         
Sbjct: 122 PNNAFRWCTERLKIKPTSRFIDDIVNSEDNEHKEAIVLVGTRKSESASRAK--------- 172

Query: 155 FHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAER 214
                   +             +       P+     ++IW  I               +
Sbjct: 173 -----SIKKHEIKGKRLTKHPLQKNVFVYSPIKELYLEEIWYIINTFESPWG---AEKNQ 224

Query: 215 PVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLV 274
                        +    +   E       RF   GCW  T   +  +  +   IE    
Sbjct: 225 LFNIYSDASADDYECPTMVSNKEHKSCGQSRF---GCWTCTVVRKDKS--ISAQIENGQE 279

Query: 275 STTSERQGRVIDRDQAGSMELK---KRQG 300
                R  R   ++Q  + E +   +R G
Sbjct: 280 WLVPLRDVRDWIQEQRNNPENRSDYRRNG 308


>UniRef50_Q8TXP0 Predicted RNA modification enzyme consisting of a
           3-phosphoadenosine 5-phosphosulfate sulfotransferase
           fused to RNA-binding PUA domain n=1 Tax=Methanopyrus
           kandleri RepID=Q8TXP0_METKA
          Length = 524

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 48/239 (20%), Positives = 86/239 (35%), Gaps = 38/239 (15%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDT 65
             ++ +   E++   RE  +  S     +S GKDS V L +A +A          L VDT
Sbjct: 215 EEYVSERLEEAVTFARENVSP-SRTFASFSGGKDSLVTLVVAAEAGVE-----RALFVDT 268

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGV----AMGINPFVHGSAKHTDIMKTEGLKQ 121
           G +  E  E  DR A+A G ++ + +    +       + P    +   T   K   + +
Sbjct: 269 GMELPETVEAADRAAEAVGIDVEIVEGDPEIFHRVTEALLPPSRDNRWCTLAAKLTPVTR 328

Query: 122 ALNKYGFDAAFG--GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
            +        +   G RR E ++R+                  +R  +W           
Sbjct: 329 YVRSEFGRGCYTLVGVRRYESEARS------------------ERGRVWD----SDAVPG 366

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
            + V P+ +W+  D+W  +  +++   PLY        +R G  M       D +  E 
Sbjct: 367 QVNVAPIFDWSSLDVWLCVHSKDLPYNPLYDEG----FDRIGCYMCPASKVGDFRLSER 421


>UniRef50_C6QHX4 Adenylylsulfate reductase, thioredoxin dependent n=1
           Tax=Hyphomicrobium denitrificans ATCC 51888
           RepID=C6QHX4_9RHIZ
          Length = 269

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 48/298 (16%), Positives = 83/298 (27%), Gaps = 92/298 (30%)

Query: 17  IHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFR 76
           I  IR             S+G +   + H    A         +  +DTG  F E  +  
Sbjct: 44  IKAIRAAID--GTIAFSTSLGIEDQAITH----AIAETGAEIDIFTLDTGRHFPETLDTL 97

Query: 77  DRTAKAYGCELLVHKNPEGVA---------MGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
             T   YG  + V                  G    V       ++ K   L +ALN  G
Sbjct: 98  FDTEGKYGLRIRVMYPDAAEVEDLVANDGIYGFRYSVDARKACCEVRKVRPLNRALN--G 155

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
             A   G RR++ + RA     ++                           + I++ P++
Sbjct: 156 AAAWVTGLRREQSQGRAHVHFATYDPAQ-----------------------KLIKLNPIA 192

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           +W+   +  Y+    I +  L+                                    F 
Sbjct: 193 DWSLATLEDYVATNKIPVNALHAKG---------------------------------FP 219

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI----DRDQAGSMELKKRQGY 301
           ++GC P T A++                    R GR      D+ + G    ++  G+
Sbjct: 220 SIGCQPCTRAIKP---------------GEDIRAGRWWWESEDKKECGLHTQREDPGF 262


>UniRef50_B1I2U8 Phosphoadenosine phosphosulfate reductase n=1 Tax=Candidatus
           Desulforudis audaxviator MP104C RepID=B1I2U8_DESAP
          Length = 755

 Score =  129 bits (323), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 43/239 (17%), Positives = 76/239 (31%), Gaps = 41/239 (17%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEF----SNPVMLYSIGKDSSVMLHLARKAFYPGTL 56
           M +   + LR +   ++  I+ V   +        + +S GKDS V+L L ++   P   
Sbjct: 85  MLERNDSILRDMVHATLDCIKAVHERYRDRVDTVAVAFSGGKDSLVLLDLVQRVLPPD-- 142

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYG-CELLVHKNP---EGVAMGINPFVHGSAKHTD 112
            F ++  DT  +    YE  +   K +G       + P           P          
Sbjct: 143 EFVVVFNDTTMELSATYEAVEAAKKRWGKLRFFTARAPRPARETWQEFGPPSRLHRWCCT 202

Query: 113 IMKTEGLKQALNKYG-----FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPEL 167
           + K+    + L +           + G RR+E  +RA     S                 
Sbjct: 203 VHKSAPTLRLLREMCGRPAVRALIYDGNRREESPARAAYPAVS----------------- 245

Query: 168 WHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI 226
                        I V PL NW   ++  Y+   ++ +   Y    R  + R G  +  
Sbjct: 246 -----EGKKHPGQINVSPLLNWGLTEVHLYLMCRDLLLNRAY----RWGVVRVGCAVCP 295


>UniRef50_Q2S6R6 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS
           reductase)/FAD synthetase and related enzyme n=2
           Tax=Oceanospirillales RepID=Q2S6R6_HAHCH
          Length = 527

 Score =  129 bits (323), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 41/290 (14%), Positives = 81/290 (27%), Gaps = 52/290 (17%)

Query: 14  AESIHIIRE----VAAEFSNPVMLYSIGKDSSVMLHLARKAF-----YPGTLPFPLLHVD 64
             ++ +I E            V+ +S GKDS+ +L L   A              ++  D
Sbjct: 23  RPALDLILEIQSLYLENDKPWVIGFSGGKDSTTVLSLIYVALTGLPEAKRHKHIYVISSD 82

Query: 65  TGWKFREMYEFRDRTAKAYG-------CELLVHKNPEG---------VAMGINPFVHGSA 108
           T  +   + +  + + +A           +  H              +  G         
Sbjct: 83  TLVETPMVVDMINDSIEAINRNAQDKKLPISAHVVYPAWNETFWVNLLGKGYPAPTQNFR 142

Query: 109 KHTDIMKTEG----LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQR 164
             T+ MK +     +K  + ++G      GAR  E  SRA+                 + 
Sbjct: 143 WCTERMKIDPVSTFIKDKIARFGEVIVVLGARSQESSSRAQ--------------VIAKH 188

Query: 165 PELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLM 224
                + +   +   +    P+ +WT  ++W Y+          +        +      
Sbjct: 189 KIEGSSLSRHSSLPGAFTYMPIEDWTFDEVWMYLLGAPAPWGGDHFELFELYKD------ 242

Query: 225 MIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLV 274
                   +           RF   GCW  T   +  A        E+ +
Sbjct: 243 SSAGECPLVIDTNTPSCGNSRF---GCWTCTVVTKDRAIEGLIDSGEVWL 289


>UniRef50_UPI000038E1FC phosphoadenosine phosphosulfate reductase n=1 Tax=Ferroplasma
           acidarmanus fer1 RepID=UPI000038E1FC
          Length = 245

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 44/290 (15%), Positives = 86/290 (29%), Gaps = 87/290 (30%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVD 64
             +L   +   + ++ ++   +    V   S+G +  V+  +  +      +   +  +D
Sbjct: 2   EEYLDLQDLNPVEMLGKIGKYYGKGAVFTSSLGLEDMVITDMIAR----NNINVEIATID 57

Query: 65  TGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAM------GINPFVH---GSAKHTDIMK 115
           TG    E Y+  +      G +L ++              GIN F H         ++ K
Sbjct: 58  TGRLPDETYQLMETVRSEMGIDLKIYFPEREDVEDMINSRGINLFYHSLDNRHFCCNVRK 117

Query: 116 TEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQI 175
            + LK  L K        G R ++  +R   R   +                       +
Sbjct: 118 VKPLKNILRKR--SVWITGIRAEQTVARKNARKVEY-----------------------V 152

Query: 176 NKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
                 +V PL +W+  +IW Y+ +  +    L+                          
Sbjct: 153 RDHNVWKVNPLLDWSRDEIWSYVSIHKVPYNILFDQ------------------------ 188

Query: 236 GEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                     ++++GC P T AV  +                 ER GR  
Sbjct: 189 ---------NYKSIGCQPCTKAVGKD---------------DDERSGRWW 214


>UniRef50_Q758M0 AEL259Wp n=1 Tax=Eremothecium gossypii RepID=Q758M0_ASHGO
          Length = 265

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 31/228 (13%), Positives = 61/228 (26%), Gaps = 34/228 (14%)

Query: 11  QLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFR 70
                   ++      F +   + + G      + +  K         PL+ +DT   F 
Sbjct: 28  AKLTSPAEVLHWAVTTFPHLYQMTAFGLTGLATIDMLSKLPALEEQMVPLIFIDTLHLFP 87

Query: 71  EMYEFRDRTAKAYGCE----LLVHKN-------PEGVAMGINPFVHGSAKHTDIMKTEGL 119
           +      +    Y       + + +              G   +     K+  I K E  
Sbjct: 88  QTLSLLHQVEDRYYKPLSQSIHIFRPAGVSTEKEFAEKYGSCLWETDEDKYDFIAKVEPA 147

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
            +A    G  A   G RR +  SR +       +                          
Sbjct: 148 HRAFRSLGVGAVLTGRRRSQGGSREQLNFVEVDEVNA----------------------- 184

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
            +++ P   W+   +W YI    I    L     + + +    L ++D
Sbjct: 185 VLKINPFVTWSFDQVWSYILDNRIPYNELLNYGYKSIGDYHSTLPVVD 232


>UniRef50_Q9JRT1 Phosphoadenosine phosphosulfate reductase n=103 Tax=Proteobacteria
           RepID=CYSH_NEIMB
          Length = 246

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 47/287 (16%), Positives = 77/287 (26%), Gaps = 87/287 (30%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L +        +  +     +     S+  +  V+  L         L   +  +DTG  
Sbjct: 24  LAEKTETLKQRLHRIVGSHRDARFASSLAAEDMVITDLIA----GENLNIGIFTLDTGLL 79

Query: 69  FREMYEFRDRTAKAY-GCELLVHKNPEGVAMGI---------NPFVHGSAKHTDIMKTEG 118
             E     DR  +AY    +   +     A               V    +   I KTE 
Sbjct: 80  HTETLNLLDRLGRAYPHLRIKRFRPVREDADRYVESKGRFAFYDSVEARRECCRIRKTEP 139

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L +A+   G DA   G RR++  +R +     +                           
Sbjct: 140 LNRAIA--GADAWLTGQRREQSATRTELPFAEYD-----------------------AGR 174

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
              +  P+ +W+E D+W YI   N+    LY                             
Sbjct: 175 GIGKYNPIFDWSEHDVWAYILANNVPYNDLYRQG-------------------------- 208

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                  F ++GC P T  V+               +    R GR  
Sbjct: 209 -------FPSIGCDPCTRPVK---------------AGEDIRAGRWW 233


>UniRef50_B1YPZ9 Sulfurtransferase DndC n=2 Tax=Proteobacteria RepID=B1YPZ9_BURA4
          Length = 484

 Score =  128 bits (321), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 45/315 (14%), Positives = 87/315 (27%), Gaps = 47/315 (14%)

Query: 14  AESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFY-----PGTLPFPLLHVDTGW 67
            + +  +RE+    +   ++ YS GKDS+  L L   A         T P  ++  DT  
Sbjct: 6   EQIVDELRELYLSDAIPWIVGYSGGKDSTASLQLLWTAIASLPKARRTKPIHVISTDTLV 65

Query: 68  KFREMYEFRDRTAKAYGC-------ELLVHKNPEG---------VAMGINPFVHGSAKHT 111
           +   +  + + + +            +  H+             +  G           T
Sbjct: 66  ENPIIAGWVEVSLQQINLAAIQQELPITAHRLTPSLENRFWVNLIGKGYPAPRPKFRWCT 125

Query: 112 DIMKTEGLKQALNK----YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPEL 167
           D +K     + + +    +G      G RR E ++R K             D        
Sbjct: 126 DRLKISASTKFIQELSENHGEAILILGQRRGESQARDKVM-----------DQYKTSTRA 174

Query: 168 WHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMID 227
             + N            P+ +WT  D+W+Y+                  L         D
Sbjct: 175 RLSKNKDPRLSRVWVYPPIESWTSDDVWEYLITHPNP-----WGISNQELFSIYRGATPD 229

Query: 228 DNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVID- 286
                +           RF   GC+  T   +  +       +E           R  + 
Sbjct: 230 AECPVVVDTSSPSCGDSRF---GCYVCTMVTQDKSMQAMIQNDEQKQWMQPILDFRNNNL 286

Query: 287 -RDQAGSMELKKRQG 300
             +     + ++  G
Sbjct: 287 AGEDRAVRDFRRMNG 301


>UniRef50_A8IWB7 FAD synthetase n=1 Tax=Chlamydomonas reinhardtii RepID=A8IWB7_CHLRE
          Length = 578

 Score =  128 bits (321), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 43/260 (16%), Positives = 76/260 (29%), Gaps = 52/260 (20%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLP- 57
           ++ I    + +   ++I  +R   A +        ++ GKDS+V+LHL R A        
Sbjct: 8   LESIPDPVVLEKSKKAIACLRRTCALYPLEKIAFSFNGGKDSTVLLHLLRAAVAQQEAAK 67

Query: 58  -------FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKH 110
                      +      F E+  F +   KAYG ++      +    G           
Sbjct: 68  GSAGLGGMLSFYFRQKDDFAEVKAFVEGADKAYGLDVEYLS-EQDFKKG----------- 115

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
                   L + L + G  A   G RR +  +  ++                        
Sbjct: 116 --------LCEYLERTGVMAIVLGTRRGDPNAGGQDVFC--------------------- 146

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
                     +RV P+ +WT  D+W ++    +    LY      +      L      R
Sbjct: 147 -PSSEGWPAFMRVNPILDWTYHDVWVFLRATRVAYCSLYDHGYTSLGGVGNTLPNNTLRR 205

Query: 231 IDLQPGEVIKKRMVRFRTLG 250
            D            R   +G
Sbjct: 206 PDGSYEPAYHLADGRLERVG 225


>UniRef50_Q39RP8 Phosphoadenylylsulfate reductase (Thioredoxin) n=7 Tax=Bacteria
           RepID=Q39RP8_GEOMG
          Length = 235

 Score =  128 bits (321), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 45/282 (15%), Positives = 81/282 (28%), Gaps = 86/282 (30%)

Query: 14  AESIHIIRE-VAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A    I+R  V+A   +  +  S   +  +++ +A++       P  +  +DTG    E 
Sbjct: 16  ATPQDILRAGVSATEGSVKLACSFSVEDVIIIDMAKEL----GCPIGIFALDTGRLHEET 71

Query: 73  YEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV-----HGSAKHTDIMKTEGLKQAL 123
           YE  D   + Y   +  +       E +      F          +   I K E L +AL
Sbjct: 72  YEVADAITERYRIPIDWYFPRHETVEKLERDKGLFSFRESLDNRHECCHIRKVEPLGRAL 131

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
              G      G RR++  +R         +                        G  +++
Sbjct: 132 K--GLAGWITGLRREQSVTRTGLAPIESDEAN----------------------GGILKI 167

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL  W+E+ +W+Y     + +  L+                                  
Sbjct: 168 NPLLEWSEEQVWEYAEKRRVPVNRLHKQG------------------------------- 196

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
             + ++GC P T  V                     R GR  
Sbjct: 197 --YPSIGCAPCTRPVAP---------------GEHPRAGRWW 221


>UniRef50_B8D5B9 Phosphoadenosine phosphosulfate reductase n=1 Tax=Desulfurococcus
           kamchatkensis 1221n RepID=B8D5B9_DESK1
          Length = 434

 Score =  128 bits (321), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 38/245 (15%), Positives = 76/245 (31%), Gaps = 32/245 (13%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
           +   + L     E++  +++          + YS G DS+  L L+++A         ++
Sbjct: 194 EANRSLLETAVNEAVGFLKKTLENVMDGIAVSYSGGADSTASLVLSQEALGHAR--IKVV 251

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---NPFVHGSAKHTDIMKTEG 118
           +VDTG     + E+  R     G    V  +       I         +   T I+K E 
Sbjct: 252 YVDTGMDLPGVKEYALRILDKLGLIPYVVSSGLDPLNEIASRGLPTRDNRWCTRILKLEP 311

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           L++   ++       G                          ++                
Sbjct: 312 LRRFYREHNIRFVIDG----------------------SRSRESSSRAETPRIGRNPLIP 349

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
           E  R+ P+  W+   +  YI    I++ PLY         R G ++    +  +L+    
Sbjct: 350 EVTRILPIKWWSRLLVQLYIVNRGIELNPLYNEGFT----RLGCILCPAMHPHELELSYT 405

Query: 239 IKKRM 243
             +  
Sbjct: 406 KNRYW 410


>UniRef50_A2BJV9 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase n=1
           Tax=Hyperthermus butylicus DSM 5456 RepID=A2BJV9_HYPBU
          Length = 472

 Score =  128 bits (321), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 42/244 (17%), Positives = 81/244 (33%), Gaps = 35/244 (14%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           + +     +   E  +I  +R    EF   ++ +S GKDS+    L       G     +
Sbjct: 216 LVEANREVIGIYERAAIRFLR-SLGEFDTIIVPWSGGKDST--AALLLALKAYGKDRVRV 272

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKN--PEGVAMGINPFVHGSAKHTDIMKTEG 118
           ++ DTG +F +   + +  A+  G E++       + +  G     HG      I+K + 
Sbjct: 273 VYGDTGTEFPDSVRYVEEVAEKLGIEVVRAYAGIDKELMRGAPLPSHGDRW-CTILKVKS 331

Query: 119 LKQALNKY--GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           +++   K   G      G R  E   R+                             +  
Sbjct: 332 IEEMAVKLAEGKTLLVVGDRDAESPRRSARPPVR-----------------------RAY 368

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
            G+ + V PL  W+   +  YI +  + + P+Y         R G  M       ++   
Sbjct: 369 TGDMLVVTPLRMWSAAHVQLYIIMNGLPLNPMYYYG----FYRIGCYMCPALRNWEIYAM 424

Query: 237 EVIK 240
              +
Sbjct: 425 TTSE 428


>UniRef50_Q3MB09 Phosphoadenosine phosphosulfate reductase n=24 Tax=Bacteria
           RepID=Q3MB09_ANAVT
          Length = 566

 Score =  127 bits (319), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 43/291 (14%), Positives = 78/291 (26%), Gaps = 46/291 (15%)

Query: 20  IREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLP-----FPLLHVDTGWKFREMY 73
           I+E+        ++  S GKDSS +L L   A              ++  DT  +   + 
Sbjct: 31  IQELYCLDEIPWIIGVSWGKDSSTVLQLVWNAIAALPPDKRTKTIHVITTDTKVENPIVS 90

Query: 74  EFRDRTAKAY-------GCELLVH----KNPEGVA-----MGINPFVHGSAKHTDIMKTE 117
            +  ++ K         G  +  H       +         G     +     T  +K  
Sbjct: 91  AWVRQSMKQLESAAQEKGMPISPHLLQPVIEDTFWVNLIGKGYPAPRNQFRWCTPRLKIN 150

Query: 118 GLKQALNK----YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNG 173
              Q + +     G      G R+ E   RA                K+Q   +    + 
Sbjct: 151 PANQFIRQIVRTNGETILVLGTRKAESTKRAATM------------KKHQAGRVRDRLSP 198

Query: 174 QINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDL 233
             +   S+   P+ +W+  ++W Y+                  L         D+    +
Sbjct: 199 NASLPNSLIYTPIEDWSNNEVWIYLNQCENP-----WGKSNKELFNLYRGATADNECPLV 253

Query: 234 QPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRV 284
                      RF   GCW  T   +  +       +E           R 
Sbjct: 254 IDTSTPSCGDSRF---GCWVCTLVSQDKSMQAMIQNDEEKQWMQPLLDLRN 301


>UniRef50_Q0ASV0 Phosphoadenylylsulfate reductase (Thioredoxin) n=5
           Tax=Alphaproteobacteria RepID=Q0ASV0_MARMM
          Length = 374

 Score =  127 bits (319), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 45/297 (15%), Positives = 81/297 (27%), Gaps = 86/297 (28%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAE--FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
           D +   + R  +     I+R+           ++ S G +++V LH+  +         P
Sbjct: 140 DDLAALNARYRDMTPQEILRDAIENKWVGKIAIMSSFGAEAAVGLHMIAQI----DPATP 195

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEG-----VAMGINPFVHGSAKHTDIM 114
           ++ +DTG  F +  +++ +     G   L    P+             +         + 
Sbjct: 196 VIFLDTGRLFAQTEQYQRQLTDQLGLTNLRLLTPDADAVAEEDNDERLWRRDPDACCTLR 255

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K   L   +  Y  DA   G +R     R    +    +                     
Sbjct: 256 KVRPLDGIIGDY--DALITGRKRFHGGGRMALPVVERIN--------------------- 292

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                 IRV PL+NW    I  Y    ++   PL                          
Sbjct: 293 ----GRIRVNPLANWDAAAIEGYFQRFDLPRHPLTDMG---------------------- 326

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
                      + ++GCW  T  V+                    R GR I + +  
Sbjct: 327 -----------YASIGCWTCTAPVQ---------------GNGDIRSGRWIGQSKTE 357


>UniRef50_B6YXY8 3'-phosphoadenosine 5'-phosphosulfate reductase n=7
           Tax=Thermococcaceae RepID=B6YXY8_THEON
          Length = 425

 Score =  127 bits (319), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 36/238 (15%), Positives = 79/238 (33%), Gaps = 32/238 (13%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           + ++   ++      S   +R+   ++   ++ +S GKDS+  L LA + F         
Sbjct: 209 LIELNQDYIDAFAEASKAFLRQ-FEDYD-IIVPWSGGKDSTATLILASEVFK----DVTA 262

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLK 120
           ++V   ++     E+ ++ A+     L+    P  +     P      +     K E L 
Sbjct: 263 IYVRMEYEMLLTDEYVEKLARKLKINLVRVDVPMPLDEFGMPIHRN--RWCTRQKVEALY 320

Query: 121 QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGES 180
           +A  ++       G R  E   R  +     R                         G+ 
Sbjct: 321 KAAGEFERPLLVVGDRDGESARRRLKPPVIERKNDIL--------------------GKF 360

Query: 181 IRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
           + V P+  W+   +  +I +   ++ PLY         R G  +       +++  + 
Sbjct: 361 LEVMPIKFWSGMMVQLFIIMRGFELHPLYYEG----FYRLGCTVCPSLAEWEVKLLKK 414


>UniRef50_B2V3F8 Putative sulfurtransferase DndC n=2 Tax=Clostridium
           RepID=B2V3F8_CLOBA
          Length = 542

 Score =  127 bits (318), Expect = 5e-28,   Method: Composition-based stats.
 Identities = 48/320 (15%), Positives = 91/320 (28%), Gaps = 47/320 (14%)

Query: 9   LRQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAF-----YPGTLPFPLLH 62
           L+Q     I  ++ V    + P V+ YS GKDS+ ++ L                  ++ 
Sbjct: 5   LQQKIHNIIDEMKMVYKNDNRPWVIGYSGGKDSTAVVQLVFNMLQSLPTEERHKDVYVVS 64

Query: 63  VDTGWKFREMYEF-------RDRTAKAYGCELLVHKNPEG---------VAMGINPFVH- 105
            DT  +   +  +        +  AK     L  +              +  G+      
Sbjct: 65  SDTLIENPIVLGYLKHNSILINEGAKKANIPLYTYMVHPDYNNTYWTNIIGKGLPTPTSI 124

Query: 106 GSAKHTDIMKTEGLKQAL----NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPK 161
                T+ +K +   + +     + G      G R+ E  +R        R+R       
Sbjct: 125 RFRWCTERLKIKPSNKFIEEKVKESGEVVVVLGVRKSESIARG----IRIRNREIEGYLL 180

Query: 162 NQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDG 221
                L + Y             P+   T  D+W  +  +N          +   L   G
Sbjct: 181 TPHVTLENTY----------VYNPIVELTTDDVWGLLLSDNGSTPWGTSNNDLFTLYTGG 230

Query: 222 MLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE-R 280
                +         +       RF   GCW  T   +  +        E  +    + R
Sbjct: 231 EG--GECPFTTTSDKDTPSCGNSRF---GCWICTVVNKDKSLNGFIKSGETWLQPLLDFR 285

Query: 281 QGRVIDRDQAGSMELKKRQG 300
           +  +  R++       +R G
Sbjct: 286 EWIISIRNRHEYRMQYRRDG 305


>UniRef50_Q3SNX7 Phosphoadenylylsulfate reductase (Thioredoxin) n=13 Tax=Rhizobiales
           RepID=Q3SNX7_NITWN
          Length = 254

 Score =  126 bits (317), Expect = 8e-28,   Method: Composition-based stats.
 Identities = 48/285 (16%), Positives = 77/285 (27%), Gaps = 86/285 (30%)

Query: 14  AESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
           A    +I             ++ S G +S+ +L    K         P++ +DTGW F E
Sbjct: 40  ASPAEVISAALRAVGRDRLALVSSFGTESAALL----KVMADVDPAIPVIFLDTGWLFEE 95

Query: 72  MYEFRDRTAKAYGCELLVHKNPEG-----VAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
              +RD    A G + +    P              +         I K E L +AL   
Sbjct: 96  TLTYRDTLIAALGLKDVRSIPPSEDALKQEDPDRELWFSDPDSCCRIRKVEPLARALQP- 154

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
            F A   G +R +   RA   +                             G  ++  P 
Sbjct: 155 -FAAWINGRKRFQGGLRADLPMVEDD-------------------------GARLKFNPF 188

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
           +N + +DI        +   PL  +                                  F
Sbjct: 189 ANASREDIEAIYASAKLPPHPLVASG---------------------------------F 215

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           R++GC P T   +               +    R GR   R +  
Sbjct: 216 RSVGCMPCTSRGQ---------------AGEDARAGRWRGRAKTE 245


>UniRef50_Q0EZE5 Phosphoadenosine phosphosulfate reductase n=1 Tax=Mariprofundus
           ferrooxydans PV-1 RepID=Q0EZE5_9PROT
          Length = 245

 Score =  126 bits (317), Expect = 8e-28,   Method: Composition-based stats.
 Identities = 49/287 (17%), Positives = 89/287 (31%), Gaps = 73/287 (25%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLL 61
            +    ++Q    S+ ++RE  A +    V   S+G  + V++ L  +          ++
Sbjct: 2   TMVDDLVQQKVDASLLLLREAVARYGDRVVYASSLGSQAMVLIDLICRYT----PGLRIV 57

Query: 62  HVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV------AMGINPFVH---GSAKHTD 112
            +DTG   ++ Y+  D   + YG  L V     G         G+N F            
Sbjct: 58  TLDTGRLPQQTYDLMDLLRERYGPVLNVLFPDAGEVRAMVDEHGVNLFYRAVANRKLCCA 117

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
           + K   L++ L+  G  A   G RRD+  +R++         +                 
Sbjct: 118 VRKVHPLQKELS--GMQAWITGRRRDQ-ANRSQITPVEDDPVYGLK-------------- 160

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
                    +  P+ +WTE DIW YI   ++    L+                       
Sbjct: 161 ---------KYNPMLDWTEADIWAYIRAHDLPYNSLHD---------------------- 189

Query: 233 LQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE 279
                        + ++GC   T A+                 T +E
Sbjct: 190 -----------SHYLSIGCACCTRAISVGEDPRSGRWWWENEDTLAE 225


>UniRef50_A1KL82 Phosphoadenosine phosphosulfate reductase n=31 Tax=Actinomycetales
           RepID=CYSH_MYCBP
          Length = 254

 Score =  126 bits (316), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 51/266 (19%), Positives = 83/266 (31%), Gaps = 83/266 (31%)

Query: 31  VMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVH 90
            ++ S   D +V++ LA K         P++ +DTG+ F E    RD     Y   +L  
Sbjct: 61  YVVASNMAD-AVLVDLAAKV----RPGVPVIFLDTGYHFVETIGTRDAIESVYDVRVLNV 115

Query: 91  KNPEGVAM-----GINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAK 145
                VA      G + F     +   + K   L + L   G+ A   G RR +  +RA 
Sbjct: 116 TPEHTVAEQDELLGKDLFARNPHECCRLRKVVPLGKTLR--GYSAWVTGLRRVDAPTRAN 173

Query: 146 ERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDI 205
             + SF + F                       + ++V PL+ WT+QD+ +YI   ++ +
Sbjct: 174 APLVSFDETF-----------------------KLVKVNPLAAWTDQDVQEYIADNDVLV 210

Query: 206 VPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTL 265
            PL                                       ++GC P T          
Sbjct: 211 NPLVREGY---------------------------------PSIGCAPCTAK-------- 229

Query: 266 PEIIEEMLVSTTSERQGRVIDRDQAG 291
                         R GR     +  
Sbjct: 230 -------PAEGADPRSGRWQGLAKTE 248


>UniRef50_Q8NFF5 FAD synthetase region n=38 Tax=Chordata RepID=FAD1_HUMAN
          Length = 587

 Score =  126 bits (315), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 41/228 (17%), Positives = 73/228 (32%), Gaps = 48/228 (21%)

Query: 9   LRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFP----LLH 62
           L +  A ++  I    A++S     + ++ GKD + +LHL   A        P    +L+
Sbjct: 376 LGKKVAGALQTIETSLAQYSLTQLCVGFNGGKDCTALLHLFHAAVQRKLPDVPNPLQILY 435

Query: 63  VDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
           + +   F E+ +F   T K Y  ++L  +     A+G     H                 
Sbjct: 436 IRSISPFPELEQFLQDTIKRYNLQMLEAEGSMKQALGELQARHP---------------- 479

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
                 +A   G RR +  S                        L             +R
Sbjct: 480 ----QLEAVLMGTRRTDPYS----------------------CSLCPFSPTDPGWPAFMR 513

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
           + PL +WT +DIW ++    +    LY      +  R+  +       
Sbjct: 514 INPLLDWTYRDIWDFLRQLFVPYCILYDRGYTSLGSRENTVRNPALKC 561


>UniRef50_C6E124 Phosphoadenosine phosphosulfate reductase n=1 Tax=Geobacter sp. M21
           RepID=C6E124_GEOSM
          Length = 784

 Score =  125 bits (314), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 48/284 (16%), Positives = 91/284 (32%), Gaps = 38/284 (13%)

Query: 11  QLEAESIHIIREVAAEF----SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            L  +++  I+E+   +    +   + +S GKDS V+L L  K      L  P++  DT 
Sbjct: 124 ALVMDTLKRIKEMYDAYVGKCNAVYIGFSGGKDSVVLLDLCHKVL---PLDVPVVFSDTD 180

Query: 67  WKFREMYEFRDRTAKAYG----CELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
            +  + Y   +     Y      ++    +         P          + K+     A
Sbjct: 181 MELPDTYRVWEEIQNRYKGRPFLKVSAKTHALENWQLFGPPSQALRWCCSVHKSTPAILA 240

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           L +                 R  ER             ++QR   + +    +     + 
Sbjct: 241 LKE-----------------RLGERSIKTLAFVGVRGEESQRRSGYEDIGDGLKSQSQVN 283

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD-----NRIDLQPGE 237
             P+  W+  ++W YI+  ++ +   Y       L R G LM         + I +   E
Sbjct: 284 AMPILAWSAHELWLYIFEHDLVVNEAYRKG----LPRVGCLMCPMSTDRQNDMIRMNFPE 339

Query: 238 VIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQ 281
            +       R+      T   +++A  + E       S  S RQ
Sbjct: 340 EVAPFADAVRSTIDREFTSEDDADA-FVYEGGWYARKSGVSLRQ 382


>UniRef50_Q1Q0N4 Similar to phosphoadenosine phosphosulfate reductase (PAPS
           reductase) n=1 Tax=Candidatus Kuenenia stuttgartiensis
           RepID=Q1Q0N4_9BACT
          Length = 290

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 45/279 (16%), Positives = 82/279 (29%), Gaps = 83/279 (29%)

Query: 15  ESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
            ++  I+     F  + ++L S+ K +SV++H     FY   L   +L +DTG+ F E  
Sbjct: 64  SAVERIQWAVDNFGMDAILLSSMQKTASVLMH----YFYSLGLENYILFIDTGYHFAETL 119

Query: 74  EFRDRTAKAYGCELLVHKNPEGVAMGINPF-------VHGSAKHTDIMKTEGLKQALNKY 126
           + RD     Y   ++       +      +       + G  +   + K       +   
Sbjct: 120 QLRDEFITRYKLNMVTLYPDLTIEQQEKLYGKKLYQYIDGQKECCRLRKEAPYLSYMKNN 179

Query: 127 GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
           G   +  G R+ E   R+K        R                            + PL
Sbjct: 180 GLMLSMVGLRQTEGGKRSKLEPLLRDPRIEG-----------------------YALHPL 216

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRF 246
            +W+++ I  Y+   +I I PL+                                    +
Sbjct: 217 FDWSDEQIESYLLENDIPIHPLH---------------------------------NKNY 243

Query: 247 RTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
            ++GC   T  V                   + R GR  
Sbjct: 244 PSIGCECCTTPVRP---------------GENPRAGRWR 267


>UniRef50_A3TKH9 Phosphoadenosine phosphosulfate reductase n=3 Tax=Actinomycetales
           RepID=A3TKH9_9MICO
          Length = 238

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 45/284 (15%), Positives = 82/284 (28%), Gaps = 85/284 (29%)

Query: 14  AESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A+++ + R  A  F     +  S+     V+ HL  +          +L ++TG+ F + 
Sbjct: 29  ADAVGVARWAAENFPGTLAVACSMA--EGVLPHLISQ----SAPGVDVLFLETGYHFSDT 82

Query: 73  YEFRDRTAKAYGCELLVH-----KNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
              R R A      ++          +    G   +    A    + K E L + L   G
Sbjct: 83  IGTRARVADELDVNVVDVLPELTVAEQDAKFGARLYERDPASCCAMRKMEPLGRTLA--G 140

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
           ++A   G RRDE  +R +  + +F ++                          +++ PL 
Sbjct: 141 YEAWVTGVRRDEAPTRTETPLVTFDEK-----------------------HGLVKINPLV 177

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
            W+  D+  Y     + I  L                                     + 
Sbjct: 178 TWSLDDVTDYALDNGVPINLLLSDG---------------------------------YP 204

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           ++GC P T  V                     R GR     +  
Sbjct: 205 SIGCEPCTKRVAP---------------GEDPRSGRWAGLSKTE 233


>UniRef50_D0TBT8 Phosphoadenosine phosphosulfate reductase n=3 Tax=Bacteroidetes
           RepID=D0TBT8_9BACE
          Length = 448

 Score =  125 bits (313), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 45/301 (14%), Positives = 85/301 (28%), Gaps = 46/301 (15%)

Query: 25  AEFSNPVMLYSIGKDSSVMLHLARKA-----FYPGTLPFPLLHVDTGWKFR-------EM 72
                 ++ +S GKDS+ +L L   A              ++  DT  +         E+
Sbjct: 20  DNLRPWIIGFSGGKDSTALLQLVWLAISEVPLEERKREVHVVCNDTLVENPVIQAYVYEV 79

Query: 73  YEFRDRTAKAYGCELLVH----KNPEGVA-----MGINPFVHGSAKHTDIMKTEGLKQAL 123
            +     A +    + V     +  +         G     +     TD MK +   + L
Sbjct: 80  LKKIKEAAVSMNMPIRVETTIPRLEDTFWVNVIGRGYPVPNNAFRWCTDKMKIKPTSRFL 139

Query: 124 ----NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
                + G      G R  E  +RAK                 +            +   
Sbjct: 140 TDQVAENGEAIILIGTRSSESTTRAK--------------SIRKHEIRGKRLTKHPHNPN 185

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVI 239
           +    P+ +   +++W  I             A    L +  M    DD        +  
Sbjct: 186 TYVYSPIKDLLLEEVWYIINAMTSP-----WGANNSELFQIYMDASADDYECPTIVTDKS 240

Query: 240 KKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTS-ERQGRVIDRDQAGSMELKKR 298
            +   + R  GCW  T   E  + T         +      R+  V +R+++ +    +R
Sbjct: 241 HRSCGQSR-FGCWTCTVVKEDKSLTSLVNKGLTWLEPLLRLRESMVEERNKSQNRLPIRR 299

Query: 299 Q 299
            
Sbjct: 300 N 300


>UniRef50_C4WUE8 ACYPI004304 protein n=2 Tax=Acyrthosiphon pisum RepID=C4WUE8_ACYPI
          Length = 321

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 47/274 (17%), Positives = 84/274 (30%), Gaps = 75/274 (27%)

Query: 15  ESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLP--FPLLHVDTGWKFR 70
           E+I +I+E   +F   N  + ++ GKD  V+L+L +       L      +   +  +F 
Sbjct: 117 EAIQVIKESIDKFTLENIFLSFNGGKDCVVLLYLFQAVLEELKLNGQIKAVFFQSDDQFS 176

Query: 71  EMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY-GFD 129
           E  ++   T   +  +L V K                      +K+  L   L +   F 
Sbjct: 177 EEEDYVQSTVNRFNLDLTVIKGE--------------------LKSG-LNDFLKENPHFC 215

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
           A+  G R+ +  S                       +L             +RV PL +W
Sbjct: 216 ASIIGTRQSDTGS----------------------TKLQFFQKTDPGWPILVRVQPLLHW 253

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTL 249
              +IW ++   +I    LY      +  +       +   ID   GE            
Sbjct: 254 NYDNIWSFLRQFSIPYCSLYDKGYTSLGNKSKSHPNPNLKYIDENTGE------------ 301

Query: 250 GCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                          +      +L  + SER+ R
Sbjct: 302 ---------------VKYWPAFLLQDSNSERENR 320


>UniRef50_D1IAI6 Whole genome shotgun sequence of line PN40024,
           scaffold_7.assembly12x (Fragment) n=3 Tax=Magnoliophyta
           RepID=D1IAI6_VITVI
          Length = 514

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 44/302 (14%), Positives = 86/302 (28%), Gaps = 88/302 (29%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAF------- 51
           + +     L+     +I+++R   A +      + ++ GKDS+V+LHL R  +       
Sbjct: 7   IRESDDRRLKTKYNNAIYVVRRALALYSVEEVALSFNGGKDSTVLLHLLRAGYFLHKREQ 66

Query: 52  ---------YPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP 102
                    +    P   ++ ++   F E+  F   TA  YG ++ + +           
Sbjct: 67  SHSNGVLTDHEVAFPIRTIYFESPSAFPEINSFTYETATTYGLQMDIIRLDFKSG----- 121

Query: 103 FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
                           L+  L      A F G R  +  +  +E+               
Sbjct: 122 ----------------LEALLEAKPIRAIFLGVRIGDPTAVGQEQF-------------- 151

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
                             +RV P+ +W+ +D+W ++    I    LY      +      
Sbjct: 152 --------SPSSPGWPPFMRVNPILDWSYRDVWAFLLACKIPYCSLYDRGYTSIGSIHDT 203

Query: 223 LMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQG 282
           +                           C        S++         +L     ER G
Sbjct: 204 VPNALL----------------------C-----VNNSSSSKEKFRPAYLLSDGRLERAG 236

Query: 283 RV 284
           R 
Sbjct: 237 RA 238


>UniRef50_A3DMN4 Phosphoadenosine phosphosulfate reductase n=1 Tax=Staphylothermus
           marinus F1 RepID=A3DMN4_STAMF
          Length = 418

 Score =  124 bits (312), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 36/203 (17%), Positives = 69/203 (33%), Gaps = 35/203 (17%)

Query: 30  PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLV 89
            ++ +S GKDS V+LH+A+  +         ++VDTG  F    ++ +  +   G E+ +
Sbjct: 217 VLVSFSGGKDSLVVLHMAKMHYGEDM--VRGIYVDTGVDFPHTRKYVEEISTMLGLEIDI 274

Query: 90  HKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD----AAFGGARRDEEKSRAK 145
            +    + +        + +   + KT   K+ L  Y           G R  E   RA+
Sbjct: 275 VRADVDILLPKKGLPTKNNRWCTLRKTHAFKKRLKWYKKRFDRILVLVGDRDSESVLRAR 334

Query: 146 ERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDI 205
           +     R+ +                             P+  W+   +  Y    ++ +
Sbjct: 335 KPPVRKREGYLE-------------------------AAPIKQWSTFLVQLYHLKYDLPL 369

Query: 206 VPLYLAAERPVLERDGMLMMIDD 228
            PLYL        R G  +    
Sbjct: 370 NPLYLKG----FYRLGCYICPAL 388


>UniRef50_Q16R18 Molybdopterin-binding n=3 Tax=Culicidae RepID=Q16R18_AEDAE
          Length = 217

 Score =  124 bits (310), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 36/227 (15%), Positives = 71/227 (31%), Gaps = 46/227 (20%)

Query: 8   HLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYP--GTLPFPLLHV 63
            L+    ++I +++   A +      + ++ GKD +V+L +  K             +++
Sbjct: 6   DLQIKLEKTIQLLKLAYATYKPEEIFLSFNGGKDCTVLLDIIMKMLPTIVSCNDLQCVYM 65

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
                F E+ EF D   K YG ++        +   I   +         +K        
Sbjct: 66  QPKEPFEEVEEFIDHCRKHYGIKIR------AIRGSIKSILEKICSENREIK-------- 111

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
                 A   G+RR +                           L           + +R+
Sbjct: 112 ------ACLMGSRRTD----------------------PYCGNLKLMQETDPGWPKMMRI 143

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
            PL +W   DIW+YI    +    LY      + ++   +   +  R
Sbjct: 144 SPLLDWNCSDIWEYILQNEVPYCSLYDRGYTSIGDKTNTIPNPNLKR 190


>UniRef50_C7JH54 Phosphoadenosine phosphosulfate reductase n=8 Tax=Acetobacter
           pasteurianus RepID=C7JH54_ACEP3
          Length = 254

 Score =  123 bits (308), Expect = 8e-27,   Method: Composition-based stats.
 Identities = 43/279 (15%), Positives = 83/279 (29%), Gaps = 84/279 (30%)

Query: 19  IIREVAAE-FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRD 77
           ++R+ +        +L S G +S+++L +  +A         +L ++TG  F +  E+R 
Sbjct: 47  LLRKASELLGDRLAVLSSFGAESALLLAMVAEA----DPAMKVLFLNTGKHFPQTLEYRQ 102

Query: 78  RTAKAYGCELLVHKNP-----EGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAF 132
             A       +    P     E        +         + K E LK  +    ++A  
Sbjct: 103 NLADFLHLSNVQDVAPQPQQVENRDPTGELWAFDPDACCALRKVEPLK--VASLPYEALV 160

Query: 133 GGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQ 192
            G +R +  +R+   I   R+                           +R+ PL+ W+ +
Sbjct: 161 TGRKRGQAVTRSTLEIVELRED------------------------GQLRLNPLAFWSAE 196

Query: 193 DIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCW 252
           DI Q +    +   PL                                     + ++GC 
Sbjct: 197 DITQEMQRRGLPPHPLVAEG---------------------------------YLSIGCA 223

Query: 253 PLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
           P T  V+                    R GR    ++  
Sbjct: 224 PCTQPVD---------------GAQDARAGRWAGLNKTE 247


>UniRef50_Q8MZ99 AT21573p n=9 Tax=Drosophila RepID=Q8MZ99_DROME
          Length = 254

 Score =  123 bits (308), Expect = 8e-27,   Method: Composition-based stats.
 Identities = 38/229 (16%), Positives = 75/229 (32%), Gaps = 45/229 (19%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFP 59
                  LR     +  +I+     +     ++ ++ GKD +V+L +  +   P  +P  
Sbjct: 28  KSESNDQLRDKLEHTEEVIKRAMTLYKPNEMMLSFNGGKDCTVLLDILARMTPPS-MPLG 86

Query: 60  LLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGL 119
            ++V +   F E+ +F D + + YG +L                     ++  ++K    
Sbjct: 87  AVYVKSANPFEELEKFVDDSVQRYGLQL--------------------RRYEGVLKVAFE 126

Query: 120 KQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGE 179
           +         A F G RR + +S                        L+           
Sbjct: 127 QLIAEDSQVKAIFLGCRRSDPES----------------------CNLYELEPTNNGWPA 164

Query: 180 SIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
            +R+FPL  W+  DIW Y+    +    LY      + +R    +    
Sbjct: 165 MMRIFPLLEWSYHDIWNYLRSNYLPYCCLYDQGYTSLGDRSSTRVNPSL 213


>UniRef50_A6CAR6 Phosphoadenosine phosphosulfate reductase n=2 Tax=Planctomyces
           RepID=A6CAR6_9PLAN
          Length = 263

 Score =  123 bits (308), Expect = 9e-27,   Method: Composition-based stats.
 Identities = 53/261 (20%), Positives = 91/261 (34%), Gaps = 48/261 (18%)

Query: 1   MDQIRLTHLRQ--LEAESIHIIREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLP 57
           + Q  L+ L +   E   + +I      F      L S+ +   V+ H+  +        
Sbjct: 4   LTQADLSDLNESFEERTPLELIHWAQEMFGTRLAALSSMQRAGCVVAHMLSEIKA----D 59

Query: 58  FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMG------INPFVHGSAKHT 111
            P+L VDTG  F+E  E RDR  + YG  ++     + +         +   V G  +  
Sbjct: 60  IPILFVDTGVLFQETLETRDRLIQEYGVNIVTLMPEKTMQEQTEELGILYLSVEGQEQCC 119

Query: 112 DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNY 171
           D+ KT+ L Q   +Y  DA  G  RR +   RA   I +                     
Sbjct: 120 DLRKTQPLIQVAEQY--DALIGSLRRADGGQRANVPILAIDPA----------------- 160

Query: 172 NGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
                    +RV  L++ ++++   Y+    I   PL+      +        +++    
Sbjct: 161 ------MNCLRVNILASLSKEEFQAYLEENQIITNPLHRQGYPTIGCNRCTTPVMESE-- 212

Query: 232 DLQPGEVIKKRMVRFRTLGCW 252
                     R  R+R LG W
Sbjct: 213 --------PGRAGRWRHLGPW 225


>UniRef50_D2BJ99 Phosphoadenosine phosphosulfate reductase n=2 Tax=Dehalococcoides
           RepID=D2BJ99_DEHSV
          Length = 342

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 57/313 (18%), Positives = 96/313 (30%), Gaps = 46/313 (14%)

Query: 10  RQLEAESIHII-REVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGT---LPFPLLHVDT 65
             L  ++I+ I RE   +     + +S GKDSS +L L   A         P  +++ DT
Sbjct: 5   NALLNDTINTIQREYLKDDLPWSLAFSGGKDSSALLKLVYVALQNIGKKLKPVTVVYCDT 64

Query: 66  GWKFREMYEFRDRT-------AKAYGCELLVHKNPEGVA---------MGINPFVHGSAK 109
           G +   +  F   T       A+     +        +           G     +    
Sbjct: 65  GVEIPIIRSFVIETLHSLQIEAEKNEIPIKTKIVTPSIEDKFFSKVIGRGYPSPTYQFRW 124

Query: 110 HTDIMKTEGLKQALNKY-GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELW 168
            TD+++ + ++   N + G      G R  E   R +       D  H            
Sbjct: 125 CTDVLRIKPIRNYTNNFNGKSIVLLGIRNGESSERDRALKKYRIDDSH------------ 172

Query: 169 HNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDD 228
             Y  Q N  +++   P+  +  +DIW  +   +  I          V +      ++D 
Sbjct: 173 --YFRQSNNMQALVFSPMLEYAVEDIWSVLKESSGPI-------SIDVDKLQMFYRVLDS 223

Query: 229 NRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE-RQGRVIDR 287
             I       +     RF   GCW  T      A           +S   E R      R
Sbjct: 224 GNIKELTSASLFNSKGRF---GCWVCTVVRRDRAVEGLITDGTESLSPLLEFRNWLSKIR 280

Query: 288 DQAGSMELKKRQG 300
            +      K+R G
Sbjct: 281 YEPSYRLNKRRNG 293


>UniRef50_UPI00016C68DD hypothetical protein CdifQCD-6_15821 n=1 Tax=Clostridium difficile
           QCD-63q42 RepID=UPI00016C68DD
          Length = 488

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 46/337 (13%), Positives = 99/337 (29%), Gaps = 54/337 (16%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAAEFSNP-VMLYSIGKDSSVMLHLARKAFY-----PG 54
           +D   L +L          ++ V      P ++ YS GKDSS ++ L  +          
Sbjct: 6   LDNNNLENL-------YDEMQAVYLNDDRPWIIGYSSGKDSSCVVELTFRMLKRLPKEKR 58

Query: 55  TLPFPLLHVDTGWKFREMYEF-------RDRTAKAYGCEL----LVHKNPEGVA-----M 98
                ++  DT  +   + ++        + +A  +   +    +  +  +         
Sbjct: 59  HKEIYVISSDTLIENPIILDYLKNNIDKINESATEHDLPISAQIVYPELNDSFWANIIGR 118

Query: 99  GINPFVH-GSAKHTDIMKTEGLKQALNKY---GFDAAFGGARRDEEKSRAKERIYSFRDR 154
           G            T+ +K +   + + +           G R++E  +R        R+ 
Sbjct: 119 GYPTPKSIKYRWCTERLKIKPSNKFIKEKLEQKDVIVLLGVRKEESSARKSR--IEKREI 176

Query: 155 FHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN----------ID 204
                  ++     +          +    P+ N++  D+W  ++ +N            
Sbjct: 177 EGYLLTPHETLRGKNKL--------AYVYTPIVNFSTADVWDVLYHQNDNFIDFGGEFGP 228

Query: 205 IVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQT 264
                   +   L +  M    D +       E   K        GCW  T   E  +  
Sbjct: 229 SPSTSWGTDAMELFQMYMKGSGDSDECPFIADEASAKSSCGNSRFGCWICTVVKEDKSLN 288

Query: 265 LPEIIEEMLVSTTSE-RQGRVIDRDQAGSMELKKRQG 300
                    +    E R   + +RD+  + +  KR G
Sbjct: 289 GFIESGHDELKPLLEFRSWLISERDKPKNRKKHKRNG 325


>UniRef50_A7RYI4 Predicted protein n=1 Tax=Nematostella vectensis RepID=A7RYI4_NEMVE
          Length = 475

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 35/240 (14%), Positives = 64/240 (26%), Gaps = 51/240 (21%)

Query: 18  HIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGT---LPFPLLHVDTGWKFREM 72
            +I+E    F      + ++ GKD +V+L++   A             L+V     F+E 
Sbjct: 278 AVIQESLKLFRLDELCISFNGGKDCTVLLYIMYAAVAQSMAEVPKINALYVRHDSPFKEA 337

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY--GFDA 130
             F + T + Y   L+                          K +   + L K      A
Sbjct: 338 ENFVEETTRLYNLNLI----------------------CMSGKIKPALEELKKSHPNIKA 375

Query: 131 AFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWT 190
              G RR +  +                       +L           E +R+ P+ +W 
Sbjct: 376 ILMGTRRHDPFT----------------------EKLHTFSWTDQGWPEYLRINPILDWN 413

Query: 191 EQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLG 250
            QD+W  +    +    LY      +                 +          +    G
Sbjct: 414 HQDVWSILLHCKVPYCTLYDNGYTSLGSSHNTRPNPVLRVNSNEYKPAYLLEDDQLERAG 473


>UniRef50_C1F5K5 Putative sulfurtransferase DndC n=1 Tax=Acidobacterium capsulatum
           ATCC 51196 RepID=C1F5K5_ACIC5
          Length = 512

 Score =  122 bits (306), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 47/320 (14%), Positives = 90/320 (28%), Gaps = 54/320 (16%)

Query: 14  AESIHIIRE-----VAAEFSNPVMLYSIGKDSSVMLHLARKAFY--PGTLPFPLLHV--- 63
            +++ ++ E       ++    V+ YS GKDS+  L L   A    P      ++HV   
Sbjct: 18  RKTLELLAENVQALYLSDEIPWVVGYSGGKDSTATLQLIWTAIAALPAEKRTKVIHVIST 77

Query: 64  DTGWKFREMYEFRD-------RTAKAYGCELLVHKNPEG---------VAMGINPFVHGS 107
           DT  +   +  + +       R+A         ++             +  G        
Sbjct: 78  DTLVENPIIAGWVNASLLTMQRSASDQDLPFRPNRLLPELKDRFWVNMIGRGYPAPRPKF 137

Query: 108 AKHTDIMKTEG----LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQ 163
              T+ +K       ++  ++  G      G R+ E + R+    +  ++         Q
Sbjct: 138 RWCTERLKINPSNNFIRNVVDDAGEVILALGTRKAESQVRSASIDHYSKNARAGLQRHGQ 197

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
               W                P+ +W+  D+WQY+              +   L      
Sbjct: 198 LDRSW-------------VFSPIVDWSNDDVWQYLMQVKNP-----WGIDNKDLLGMYQG 239

Query: 224 MMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
              D     +           RF   GC+  T   E  +       +          Q R
Sbjct: 240 ATEDGECPLVVDTSTPSCGDSRF---GCYVCTMVTEDKSMRSMIANDSDKAWMLPLLQFR 296

Query: 284 VID---RDQAGSMELKKRQG 300
                  +     E K+  G
Sbjct: 297 NQYLGNLNDRNVREFKRLNG 316


>UniRef50_C3XHV9 Phosphoadenosine phosphosulfate reductase n=1 Tax=Helicobacter
           bilis ATCC 43879 RepID=C3XHV9_9HELI
          Length = 471

 Score =  122 bits (306), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 49/327 (14%), Positives = 93/327 (28%), Gaps = 53/327 (16%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLP--- 57
             I+ T L  +  ++ + ++      +   ++ +S GKDS+ +L L  +           
Sbjct: 17  KHIKETSLNDIITQTKNELKRQFLSTTRAWIIAFSGGKDSTCILQLFYEMLVSLPKHLQR 76

Query: 58  ----------FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEG---------VAM 98
                         H+DT      + +  +  AK       + +             +  
Sbjct: 77  QSYAIASNTLVEAPHIDTFLHN--VLDSINTHAKNNDIPFSILQVSPSLQDDFWVNLIGK 134

Query: 99  GINPFVHGSAKHTDIMKTEGLK----QALNKYGFDAAFGGARRDEEKSRAKERIYSFRDR 154
           G           TD +K    +        + G      G R  E  +R K         
Sbjct: 135 GYPSPTRTFRWCTDRLKITPSRIEVANITKQAGSALLVLGTREQESTNRKK--------- 185

Query: 155 FHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAER 214
                   +R      ++   +   ++   PLS W+  D+W Y+        PL+     
Sbjct: 186 -----SMQKRILNNQGFSKHDDFPNTMTYAPLSKWSTDDVWAYLSTHK----PLWDKDHS 236

Query: 215 PVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLV 274
            + +         D    +           RF   GCW  T   E  +        E  +
Sbjct: 237 ELFKL--YAKASGDECQFITHLAQSSCGGSRF---GCWVCTVVSEDKSLQGFIDTGENHL 291

Query: 275 STTSE-RQGRVIDRDQAGSMELKKRQG 300
              ++ R      R+   +    KR G
Sbjct: 292 KPLNDFRNYIKRLREDKLARADYKRDG 318


>UniRef50_Q8GA37 Z1203 protein n=70 Tax=Bacteria RepID=Q8GA37_ECOLX
          Length = 410

 Score =  122 bits (306), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 43/243 (17%), Positives = 70/243 (28%), Gaps = 42/243 (17%)

Query: 15  ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
            +IH I  +   FS+  + +S GKDS+V+LHLA          F +L +D   +++   E
Sbjct: 19  AAIHRIEWLFETFSSVCLSFSGGKDSTVLLHLAADVARRKKRRFSVLFIDWEAQYQCTIE 78

Query: 75  FRDRTAKAYG----------CELLVHKNPEGVAMGINPF-------VHGSAKHTDIMKTE 117
              +  + Y             L               +        H        M   
Sbjct: 79  HVQKMREMYRDVTDTFYWVALPLTTVNGVSQFQPEWICWEPDVTWVRHPPEYAITDMAYF 138

Query: 118 GLKQALNKYGF---------------DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKN 162
              +    +                  A   G R DE  +R                 + 
Sbjct: 139 PFYRYAMTFEEFVPAFSSWFAGNRCGVAILTGVRADESLNRF----------MGLVSQRK 188

Query: 163 QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGM 222
            R      +     +G    ++PL +W  +DIW Y         PLY    R  +    M
Sbjct: 189 LRYADDKPWTTASPEGFYYTMYPLYDWKARDIWIYNARTRAIYNPLYDLMYRAGVPLRNM 248

Query: 223 LMM 225
            + 
Sbjct: 249 RVC 251


>UniRef50_B8FTN0 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=6 Tax=Clostridia
           RepID=B8FTN0_DESHD
          Length = 250

 Score =  122 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 46/269 (17%), Positives = 81/269 (30%), Gaps = 73/269 (27%)

Query: 14  AESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFRE 71
            +   ++  V  +       +  S+  +  V+  +  K          +  +DTG  F++
Sbjct: 20  EDPRKLLAHVVEKIGPARIALASSLSIEDQVLTQMLLKIDARAR----IFFIDTGRNFQQ 75

Query: 72  MYEFRDRTAKAYGCELLVHKNPEG------VAMGINPFVHG---SAKHTDIMKTEGLKQA 122
            Y+  + T   Y     V+              G N F        K  ++ K   L++ 
Sbjct: 76  TYDLMEETMSRYEFHYEVYAPENSELEPFLAEYGPNAFYDKVELRQKCCELRKVRSLQRV 135

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           L+    D    G R+++  +R +  +  +  R                           +
Sbjct: 136 LST--VDGWICGLRKEQSPTRQEIGLLEWDSR-----------------------HAIYK 170

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           V PL+ W+E+ +W YI  ENI    LY                                 
Sbjct: 171 VNPLAAWSEEQVWAYIRRENIPYSSLYNKG------------------------------ 200

Query: 243 MVRFRTLGCWPLTGAVESNAQTLPEIIEE 271
              FR++GC P T AV   A         
Sbjct: 201 ---FRSIGCQPCTRAVAPGADVRSGRWWW 226


>UniRef50_Q2RT16 Phosphoadenylylsulfate reductase (Thioredoxin) n=1
           Tax=Rhodospirillum rubrum ATCC 11170 RepID=Q2RT16_RHORT
          Length = 242

 Score =  122 bits (305), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 49/298 (16%), Positives = 87/298 (29%), Gaps = 91/298 (30%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           EA    +++          ++ S G +++ +LH+            P+L VDTG  F E 
Sbjct: 24  EAILEDVLKRAFVR--RTALVSSFGTEAAALLHMVAAI----EPATPVLFVDTGRLFGET 77

Query: 73  YEFRDRTAKAYGC-ELLVHKNPE---GVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF 128
             +RDR  +  G  ++   K           +  F   + +   + K   L++AL   GF
Sbjct: 78  LRYRDRLVERLGLTDVRSLKPEPRIAAEDQDLMLFSRDADRCCYLRKVLPLRKALE--GF 135

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
           D    G +      RA+  +                             G  +++ PL+ 
Sbjct: 136 DCWINGRKGHHGGGRAQMPVAEAD-------------------------GFLVKITPLAR 170

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           W   D+  Y    ++   PL+                                    F +
Sbjct: 171 WGADDVDAYYETHDLPRHPLWEDG---------------------------------FPS 197

Query: 249 LGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG------SMELKKRQG 300
           +GC P T    +                   R GR     +          E+ +R G
Sbjct: 198 VGCLPCTVRASAEDGF---------------RAGRWAGAQKTECGIHLPVAEVLRRAG 240


>UniRef50_D1HPZ6 Whole genome shotgun sequence of line PN40024,
           scaffold_116.assembly12x (Fragment) n=1 Tax=Vitis
           vinifera RepID=D1HPZ6_VITVI
          Length = 438

 Score =  121 bits (304), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 49/284 (17%), Positives = 84/284 (29%), Gaps = 100/284 (35%)

Query: 14  AESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           A  + I+ +  A+F N   + +S G +   ++  AR                TG  F   
Sbjct: 96  ASPLEIMDKALAKFGNDIAIAFS-GAEDIALIEYARL---------------TGRPF--- 136

Query: 73  YEFRDRTAKAYGCELLVHKNP----EGVAMGINPFV---HGSAKHTDIMKTEGLKQALNK 125
                   K YG  +          +G+      F     G  +   + K   L++AL  
Sbjct: 137 -------RKHYGIRIEYMFPDAVEVQGLVRSKGLFSFYEDGHQECCRVRKVRPLRRALK- 188

Query: 126 YGFDAAFGGARRDEEK-SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            G  A   G R+D+   +RA+  +      F   D                  G  ++  
Sbjct: 189 -GLRAWITGQRKDQSPGTRAEVPVVQVDPAFEGLDG---------------GVGSLVKWN 232

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P++N    DIW ++   N+ +  L+                                   
Sbjct: 233 PVANVQGMDIWNFLRAMNVPVNSLHSKG-------------------------------- 260

Query: 245 RFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRD 288
            + ++GC P T  V               +    ER+GR    D
Sbjct: 261 -YISIGCEPCTRPV---------------LPGQHEREGRWWWED 288


>UniRef50_Q0RWS5 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=6
           Tax=Actinomycetales RepID=Q0RWS5_RHOSR
          Length = 284

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 41/242 (16%), Positives = 73/242 (30%), Gaps = 21/242 (8%)

Query: 19  IIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDR 78
            I +   +     + +S GKDS V LHL  +         P++  D+G ++ E Y +   
Sbjct: 31  RIEQHLDDHDG-YLAFSGGKDSLVALHLTLQV----EPNIPVVFFDSGLEYPETYTYITA 85

Query: 79  TAKAYGCELLVHKNPE---GVAMGINPFVHGSAKHTDIMKTE------GLKQALNKYGFD 129
            A  +   L  H+       V      + H         K          + A   +G  
Sbjct: 86  LADTWNLNLEPHRADPPLLTVLAQSGEWDHQQPTRATSQKLREILIGAPSRAAHATHGP- 144

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR------V 183
               G R DE           +                      + + G   R       
Sbjct: 145 GEIWGVRADESPKGTGRWSLYYNALSSHVTRDCDGCCTNTTEQRRHHGGLIDRADGTHVF 204

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            P+ +W+  +IW YI    + + P+Y    R       + +    +   L+ G + + R 
Sbjct: 205 GPMWDWSVDEIWAYIAHHQLPVNPVYDTLRRLGTPEKHLRVSHMLDGAFLEHGRITRLRR 264

Query: 244 VR 245
             
Sbjct: 265 GW 266


>UniRef50_Q11WI2 Phosphoadenylylsulfate reductase (Thioredoxin) n=3 Tax=Bacteria
           RepID=Q11WI2_CYTH3
          Length = 220

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 47/278 (16%), Positives = 78/278 (28%), Gaps = 84/278 (30%)

Query: 20  IREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRT 79
           + E   +        S    S V+LH+  +         P+  ++TG+ F E   +RD+ 
Sbjct: 10  LTEYQEKGLKLFTTSSFQTHSIVLLHILSE----FDPSIPVYFINTGYHFPETVLYRDQI 65

Query: 80  AKAYGCELLVH------KNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFG 133
           A  +  + +        +N +  A G   F         + K + L   L  Y  D    
Sbjct: 66  ADLFNLKNIKVVSSATPRNMQKDAEGRLLFTSDPDYCCYLNKVQPLDAVLPDY--DIWIN 123

Query: 134 GARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQD 193
           G R D+   R    +                         Q    ++IR  P+ +W  + 
Sbjct: 124 GVRADQSAVRKSFSV------------------------EQPAPHDTIRFHPMLDWDVRM 159

Query: 194 IWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWP 253
           I +YI    I   PL                                     + ++GC P
Sbjct: 160 IEKYIKEHKIPRHPLEEKG---------------------------------YLSIGCEP 186

Query: 254 LTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAG 291
            T                     T  RQGR    ++  
Sbjct: 187 CTRK---------------FDLETYNRQGRWFGLNKTE 209


>UniRef50_A3UEI0 Phosphoadenosine phosphosulfate reductase n=1 Tax=Oceanicaulis
           alexandrii HTCC2633 RepID=A3UEI0_9RHOB
          Length = 366

 Score =  121 bits (303), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 55/300 (18%), Positives = 91/300 (30%), Gaps = 89/300 (29%)

Query: 9   LRQLEAESIHII--REVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTG 66
            ++L+  +   I  R          ML S G ++++ L L  +         P+L +DTG
Sbjct: 136 AKELDGATPEAILCRAAQVYGGRMAMLSSFGAEAALGLALVAEIAS----DTPILFLDTG 191

Query: 67  WKFREMYEFRDRTAKAYGC-ELLVHKNPEGVAMGINP----FVHGSAKHTDIMKTEGLKQ 121
             F +   +RDR  K  G   L + K  E      +P    +        D+ K   L +
Sbjct: 192 MHFPQTLSYRDRLVKHLGLTNLHILKPDEAELRNEDPDNRLYDRDGVACCDLRKVRPLGR 251

Query: 122 ALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESI 181
           AL+   FDA   G +R     R       F                          GE +
Sbjct: 252 ALDP--FDALITGRKRYHGGQRGDIAAVEFD-------------------------GERV 284

Query: 182 RVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKK 241
           ++ P +  + QD+       ++   PL                                 
Sbjct: 285 KINPFAFLSPQDVADRYKALDLPRHPLAEDG----------------------------- 315

Query: 242 RMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRV--IDRDQAGSMELKKRQ 299
               + ++GCWP T   +                    R GR    DRD+ G  +  + +
Sbjct: 316 ----YASIGCWPCTAPADEPGS----------------RDGRWAGQDRDECGIFDPARAE 355


>UniRef50_UPI0001C36A5F hypothetical protein ChatD1_04226 n=1 Tax=Clostridium hathewayi DSM
           13479 RepID=UPI0001C36A5F
          Length = 263

 Score =  121 bits (302), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 47/272 (17%), Positives = 83/272 (30%), Gaps = 33/272 (12%)

Query: 35  SIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAY---GCELLVHK 91
           S GKDS+V+  LA    Y   +PF ++H  T   + E   +  R  K +   G    V  
Sbjct: 4   SGGKDSNVIKQLA----YLSGVPFEIVHNHTTVDYPETVYYVRREKKRWEKLGISYTVSY 59

Query: 92  NPEGVAMG--------INPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSR 143
                             P +       ++ K        ++        G R +E   R
Sbjct: 60  PTYKGKRTTFWELIPLKGPPLRHRRWCCNVPKE-------SQNCNRYIITGVRWEESARR 112

Query: 144 AKERI-YSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN 202
            + R  Y  +             +              + V P+ +WT  ++W++I    
Sbjct: 113 KQNRAAYEIQRTTKDRIKLQNDNDAKRKLMEICQVKGKVIVNPIIDWTTTEVWEFIDRYQ 172

Query: 203 IDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNA 262
           I   PLY    + +    G  M+ +   ++  P           + +   P +       
Sbjct: 173 IVTNPLYQEGHKRIGC-VGCPMVDNKYELEKNPEFKRMYLNAFQKCVENKPPSRHGWKTG 231

Query: 263 QTLPEIIEEMLVSTTSERQGRVIDRDQAGSME 294
           Q L +              GR +D DQ    +
Sbjct: 232 QELYDWWVN---------GGRGMDSDQLCLFD 254


>UniRef50_B7UDE0 Adenosine phosphosulfate reductase n=1 Tax=Corynebacterium
           ammoniagenes RepID=B7UDE0_CORAM
          Length = 270

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 49/230 (21%), Positives = 80/230 (34%), Gaps = 39/230 (16%)

Query: 10  RQLEAESIHIIREVAAEF-SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           +  +A +  I+   A        +  S+  +++V+  LA KA     L   LL +DTG+ 
Sbjct: 57  KLFDATATDIMAWAAEHAPGRLAVTMSM--ENTVLAELAAKA----GLDADLLFIDTGFH 110

Query: 69  FREMYEFRDRTAKAY-GCELLVHKN-----PEGVAMGINPFVHGSAKHTDIMKTEGLKQA 122
           F E  E  D   K Y    L   K       +    G   +    A +  + K E L  A
Sbjct: 111 FPETLETADAVEKRYPQLPLKRIKPLLSPEQQDEIYGPRMYSWDLAAYNRMRKVEPLNMA 170

Query: 123 LNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIR 182
           +++Y       G RR + + RA+    S                              ++
Sbjct: 171 MDEY--AGWITGLRRADSEHRAQAPALSLDRT------------------------GRLK 204

Query: 183 VFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
           + P+  W   D  +YI  EN+ I PL L   R +        + D +   
Sbjct: 205 ISPIITWDLADTDKYIADENLVIHPLTLQGYRSIGCAPVTFPVGDGDDAR 254


>UniRef50_O74841 Probable FAD synthetase n=2 Tax=Schizosaccharomyces
           RepID=FAD1_SCHPO
          Length = 265

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 36/260 (13%), Positives = 62/260 (23%), Gaps = 54/260 (20%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLP-- 57
              +L  L+   + S+  I      +      M ++ GKD  V+  L             
Sbjct: 20  PSEKLVGLQNRLSISLRFIEYAFETYQPERLAMSFNGGKDCLVLFLLCIYYLKEKYKEQA 79

Query: 58  ------FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHT 111
                  P + V    +F EM +F +     Y   ++    P                  
Sbjct: 80  QAKLSNIPFVFVRPRDEFPEMDDFVNECQSKYRLNIIKISLP------------------ 121

Query: 112 DIMKTEGLKQALNKYG-FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
             MK E   + L ++    A   G RR                                 
Sbjct: 122 --MK-EAFCKFLKEHKHIQAILIGIRR----------------------LDPHGLHRIAF 156

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNR 230
                   + +R+ P+ +W+  +IW  +   N     LY      +              
Sbjct: 157 EVTDKGWPKFMRIQPILDWSYTEIWDLLLETNTKYCSLYDRGYTSLGGVSDTSPNPALKN 216

Query: 231 IDLQPGEVIKKRMVRFRTLG 250
            D                 G
Sbjct: 217 PDGTYSPAYLLSDGSLERAG 236


>UniRef50_UPI00005251CA PREDICTED: similar to FAD1 flavin adenine dinucleotide synthetase
           homolog n=1 Tax=Ciona intestinalis RepID=UPI00005251CA
          Length = 516

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 40/280 (14%), Positives = 73/280 (26%), Gaps = 77/280 (27%)

Query: 11  QLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPF-----PLLHV 63
                S+ ++ E   ++      + ++ GKD + +LHL   A     +         L++
Sbjct: 306 HKVKSSLEVLEETLRKYEPHEICVGFNGGKDCTALLHLYHAALCRAGIEINPTNFKALYI 365

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL 123
              + F E+ +F + +   Y   L         A                   E LK+  
Sbjct: 366 KDKYPFEEVEQFMESSVIRYKFHLTTMTGDMKQA------------------LEALKR-- 405

Query: 124 NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRV 183
           +     A   G R                             +L        +    +RV
Sbjct: 406 DHPSIKAVVMGTR----------------------CSDPHSMDLSSFTMTDSDWPRFMRV 443

Query: 184 FPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRM 243
            PL +WT  D+W+++    +    LY      +  RD             +         
Sbjct: 444 NPLLHWTYHDVWKFMRKLYLPYCVLYDKGYTSLGSRDKTERN-------KKLLTTNIHGS 496

Query: 244 VRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
             +                     +    L     ER GR
Sbjct: 497 SMY---------------------LPAYTLQDGDLERNGR 515


>UniRef50_UPI0000DB7DE3 PREDICTED: similar to CG4407-PA, isoform A n=1 Tax=Apis mellifera
           RepID=UPI0000DB7DE3
          Length = 390

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 44/275 (16%), Positives = 78/275 (28%), Gaps = 86/275 (31%)

Query: 17  IHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLP-FPLLHVDTGWKFREMY 73
              ++ +  ++      + ++ GKD +V+LHLA        +     L+V     F E+ 
Sbjct: 193 KQFLKMLKMKYKPEEIFISFNGGKDCTVVLHLAACITKLQNISSLLCLYVIAE-PFPEVD 251

Query: 74  EFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQAL-----NKYGF 128
            F ++  + Y  EL+                          K   ++ AL      +   
Sbjct: 252 SFVEKAVQYYDLELIK-------------------------KKSPMRLALCSLLNERTNI 286

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
            A+  G R+ +  S                        L        N    IRV P+ N
Sbjct: 287 KASLMGMRKGDPGS----------------------ENLEAFTPTDSNWPNLIRVNPILN 324

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
           W+   IW+++   N+   PLY      +  +   +                         
Sbjct: 325 WSYDQIWKFLLKHNVPYCPLYDKGYTSLGTKSTTIPNPRL-------------------- 364

Query: 249 LGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                          T        L   ++ERQGR
Sbjct: 365 ----------RDPNDTSLYFPAYTLTDESTERQGR 389


>UniRef50_B1YE28 Phosphoadenosine phosphosulfate reductase n=1 Tax=Thermoproteus
           neutrophilus V24Sta RepID=B1YE28_THENV
          Length = 392

 Score =  120 bits (301), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 56/316 (17%), Positives = 92/316 (29%), Gaps = 64/316 (20%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGT---LPFPLLHVDT 65
           L  L +E+  +  E A ++   V+ +S GKDS+    L  K             LLH DT
Sbjct: 3   LDLLLSEAFEVFEEAALKYRTFVIAFSGGKDSTAAAILFYKWAKRRNGVKNRVVLLHNDT 62

Query: 66  GWKFREMYEFRDRTA-------KAYGCELLV---HKNPEGVAM------GINPFVHGSAK 109
             +  EM  + D  A       +  G ++ V   + +P           G          
Sbjct: 63  LSEIPEMELWVDHFARQFKAKMRELGTDVHVRYAYPHPTETWYWRVLVRGYPAPTFNFRW 122

Query: 110 HTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWH 169
             D++K E  ++ L ++       G+R +E  +RAK     F                  
Sbjct: 123 CVDMLKIEPTERELRRHANHVLVVGSRDEESGARAKSMKTRFGTCSGGG----------S 172

Query: 170 NYNGQINKGESIRVFPLSNWTEQDIWQYIWLEN----IDIVPLYLAAERPVLERDGMLMM 225
                 + G+  ++ P+  WT   +W ++  +       +  LY                
Sbjct: 173 CLGAYFSHGDIPKIAPIRFWTYDMVWSFLRAQKDFDVQPLEELY---------------- 216

Query: 226 IDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                   +          R+   GCW  T      A              T  R     
Sbjct: 217 --------RGLAAGGSLGGRY---GCWHCTLVRVQAANYSRPEYLYAEAVRTIYRAL--- 262

Query: 286 DRDQAGSMELKKRQGY 301
             D        K  GY
Sbjct: 263 -SDMGQHFREPKNTGY 277


>UniRef50_A5G4D4 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS
           reductase)/FAD synthetase-like protein n=5 Tax=Bacteria
           RepID=A5G4D4_GEOUR
          Length = 551

 Score =  120 bits (301), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 42/295 (14%), Positives = 77/295 (26%), Gaps = 50/295 (16%)

Query: 14  AESIHIIRE-----VAAEFSNPVMLYSIGKDSSVMLHLARKAFYP-----GTLPFPLLHV 63
             +I +++E       A+    ++ YS GKDS+  L L   A               +  
Sbjct: 52  QATIELLQEEIRSLYIADEIPWIIGYSGGKDSTATLQLVWTAIAELPAEQRRKTVYAIST 111

Query: 64  DTGWKFREMYEFR-------DRTAKAYGCELLVHKNPEG---------VAMGINPFVHGS 107
           DT  +   +  +         R +      +   +             +  G     H  
Sbjct: 112 DTMVENPVVAAWVANSLAVMKRASAEQLVPIQPRRLTPALVDSFWVNLIGKGYPAPRHKF 171

Query: 108 AKHTDIMKTEGLKQALNK----YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQ 163
              T  +K       +N             G R+ E  +RA                +++
Sbjct: 172 RWCTARLKISPSNSFINSIVSSSVEAILVLGTRKAESSARA------------ANMARHE 219

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
           +  +    +   +   S+   P+  WT  D+W Y+                  L      
Sbjct: 220 KGRVRDRLSPNSSLPGSLVYSPIEAWTNDDVWFYLMQVKNP-----WGYNNRDLLGMYAG 274

Query: 224 MMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTS 278
              D     +           RF   GCW  T   +  + T     +E       
Sbjct: 275 ASADGECPLVVDDSTPSCGDSRF---GCWVCTLVDKDKSMTAMIQNDEEKEWMMP 326


>UniRef50_A1UQ75 Phosphoadenosine phosphosulfate reductase n=3 Tax=Mycobacterium
           RepID=A1UQ75_MYCSK
          Length = 278

 Score =  120 bits (300), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 40/204 (19%), Positives = 73/204 (35%), Gaps = 15/204 (7%)

Query: 17  IHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFR 76
           +  I E   E     + +S GKDS+V++ LAR+         P++  D+G +F E  E+ 
Sbjct: 29  LDRIAEHLDEHDG-YVSWSGGKDSTVVVDLARQV----DPHVPVVFFDSGLQFPETIEYL 83

Query: 77  DRTAKAYGCELLVHKNPEGVAM------GINPFVHGSAKH---TDIMKTEGLKQALNKYG 127
            + A A+  +  V      +        G +             DIM T    +A  ++G
Sbjct: 84  QQLASAWRLDYHVVTADPDLLTVLIAGGGFDHHAVDRRLRGQLADIMITGPAAEAHRRHG 143

Query: 128 FDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
              +  G R +E   R            H     ++                ++   P+ 
Sbjct: 144 -RGSLWGVRAEESHGRRMLYRRGLAAETHARQNCSREDVRARAGGVVRRADGTVTYGPIW 202

Query: 188 NWTEQDIWQYIWLENIDIVPLYLA 211
           +W    +++Y+    I+  PLY  
Sbjct: 203 DWQRSHVFEYLAGRGIEPNPLYRK 226


>UniRef50_C7IJX0 Phosphoadenosine phosphosulfate reductase n=1 Tax=Clostridium
           papyrosolvens DSM 2782 RepID=C7IJX0_9CLOT
          Length = 334

 Score =  120 bits (300), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 50/320 (15%), Positives = 95/320 (29%), Gaps = 49/320 (15%)

Query: 5   RLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTL-----PFP 59
               L  L  E  ++     ++    ++ YS GKDS+V++HL               P  
Sbjct: 7   NENTLEDLMKEIEYV---YLSDNRPWIIGYSGGKDSTVVVHLVYTMLLQLDPQKRHKPVY 63

Query: 60  LLHVDTGWKFREMYEFRDRT-------AKAYGCELL--VHKNPEGVAMGINPFVHG---- 106
           ++  DT  +   + E+           AK     L   + +         N    G    
Sbjct: 64  VVSSDTMVENPLIKEYLSDMITAIGNAAKRDKVPLTCKLVQPDPSNTFWANVIGRGFPTP 123

Query: 107 -----SAKHTDIMKTEG----LKQALNKYGFDAAF-GGARRDEEKSRAKERIYSFRDRFH 156
                    TD +K       ++  +NK+  +     G R+DE  +R K      R+   
Sbjct: 124 RLNGSFRWCTDRLKIAPSGTFIENIINKHNSEVVILLGVRKDESITRKKR--IEDREIIG 181

Query: 157 RWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
           +   +++  +  + Y             P+   T +D+W  I   N              
Sbjct: 182 KLLNRHETIKDAYVYP------------PIVELTTEDVWDIISSNN---NIAAWGTSNSR 226

Query: 217 LERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST 276
           +          +        +  + +       GCW  T   E  +           +  
Sbjct: 227 IIELYAGADSGECPFAGVSSKNEQTQSCGQSRFGCWICTVVKEDKSLNGFIRSGHRELIP 286

Query: 277 TSE-RQGRVIDRDQAGSMEL 295
            +E R+  +  RD   + E 
Sbjct: 287 LAEFRKWLISIRDIEANREK 306


>UniRef50_B7FZY6 Predicted protein (Fragment) n=2 Tax=Bacillariophyta
           RepID=B7FZY6_PHATR
          Length = 403

 Score =  119 bits (299), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 37/287 (12%), Positives = 76/287 (26%), Gaps = 73/287 (25%)

Query: 12  LEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYP-------------GTL 56
           +  ++++ +      +     +  ++ GKD+ V+LHL R A                  L
Sbjct: 1   MVEQALNNLDHAYRLYGPESVICSFNGGKDAVVILHLVRAAHARFYDQQRNLDGNPIEPL 60

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
              +++ +   +F E+  F       Y  +++  +     + G+   V  +      +  
Sbjct: 61  RPRVVYFEHKDEFPEIRSFLREMVDVYELDMIAFEQGIKFSEGLKTLVTHNVPQNSNVSF 120

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
                        A   G R  +  +R +                               
Sbjct: 121 -----------PVAFVLGTRATDPNARGQGTF----------------------APSSHY 147

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
               +RV P+  WT   +W ++ L ++    LY      +      +             
Sbjct: 148 MPPFMRVNPVLEWTYGHVWHFLRLFHLPYCGLYDQGYTSLGTTKDTIPCPALTVPGGNTT 207

Query: 237 EVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
             I     R+                         ML     ER GR
Sbjct: 208 NAIP----RY---------------------WPAYMLRDWDQERAGR 229


>UniRef50_Q1VVA9 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS
           reductase)/FAD synthetase and related enzyme n=1
           Tax=Psychroflexus torquis ATCC 700755 RepID=Q1VVA9_9FLAO
          Length = 229

 Score =  119 bits (299), Expect = 9e-26,   Method: Composition-based stats.
 Identities = 33/251 (13%), Positives = 72/251 (28%), Gaps = 69/251 (27%)

Query: 17  IHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           I  I+ +  +F     ++  S    S+ +L L  +          +  +DTG+ F E  +
Sbjct: 28  IDRIKALYEDFDESEIMLTSSFAATSAFLLKLFSEV----NTDQIIYFIDTGYHFDETIK 83

Query: 75  FRDRTAKAYGCELLVHKN---PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAA 131
           ++ + ++ Y   +   K              +         I K + L+  + K  +   
Sbjct: 84  YKKQLSETYNLNVKSVKALAHEHEFTTKDKTWSENPDLCCSINKVKPLE--VIKNKYTVW 141

Query: 132 FGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTE 191
             G    +   R    I+  R                         G+ ++ +PL + ++
Sbjct: 142 VSGLMEWQSDHRNSLDIFEQR-------------------------GDILKFYPLVDVSK 176

Query: 192 QDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGC 251
           Q    +I   ++   PL                                     + ++GC
Sbjct: 177 QQRDDFIKAHDLPFHPLVSKG---------------------------------YNSIGC 203

Query: 252 WPLTGAVESNA 262
              T   E  +
Sbjct: 204 QHCTVPGEDRS 214


>UniRef50_Q4P7E8 Putative uncharacterized protein n=1 Tax=Ustilago maydis
           RepID=Q4P7E8_USTMA
          Length = 402

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 50/338 (14%), Positives = 94/338 (27%), Gaps = 88/338 (26%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGT---- 55
              R   L +    ++ +  +V  E    +  + ++ GKD +V++H+             
Sbjct: 88  TAQRYPELARKVQSAVQLCEQVIHEVGQQHCALSFNGGKDCTVLVHILSAVLRRLNRLDS 147

Query: 56  -----------LPFPLLHVDTGWKFREMYEFRDRT-AKAYGCELLVHKNPEGVAMGINPF 103
                       P P L++     F  + +F     +  +G  L V     G+  GI  +
Sbjct: 148 GVNADSSTSPIPPIPSLYITCPSPFPTVEKFIRFCVSPTHGYNLQVISVHGGMKKGIRTY 207

Query: 104 VHGSAKHT-------DIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFH 156
           + G  +         D +    ++++       A F G RRD+                 
Sbjct: 208 LDGGGREQVGITRTSDALTHADVRESRKPRDIRAMFVGTRRDD----------------- 250

Query: 157 RWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIW----------------- 199
                   P+L        +     R+ P+ +W+ QD+W ++                  
Sbjct: 251 -----PHGPQLCARSWTDKDWPRVERIHPILDWSYQDVWHFLRCPHLASNDASIGWSRQE 305

Query: 200 -----------LENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRT 248
                       + +    LY      +      L        D Q     ++       
Sbjct: 306 LATHWGTAGGGDQGVPYCLLYDQGYTSLGSTHNTLPNPKLRMDDEQQTSSTEQP------ 359

Query: 249 LGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVID 286
                    V             ML   + ER GRV D
Sbjct: 360 -------VLVGDGTAKGRWRPAYMLKDASFERAGRVQD 390


>UniRef50_D0JAV6 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=10
           Tax=Bacteroidetes RepID=D0JAV6_BLASB
          Length = 244

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 53/296 (17%), Positives = 88/296 (29%), Gaps = 88/296 (29%)

Query: 10  RQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
           +++++ S+    +  + F     V   S   +  ++ H          +P  +  +DTG 
Sbjct: 19  KEIKSPSVEEKLKTLSNFFPGKIVFSTSFNIEDQLISHFIL----SNKIPIKIFTLDTGR 74

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGV------AMGINPFV---HGSAKHTDIMKTEG 118
            F E Y+  + T K YG  +  +   +          G N F        K   + K E 
Sbjct: 75  FFEETYKVWENTNKFYGYSISAYYPDQEKLEEFLSKNGPNSFYNNVKNRIKCCFLRKVEP 134

Query: 119 LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKG 178
           LK+AL   G      G R +    R K     +  ++H                      
Sbjct: 135 LKRALK--GNFVWITGLRAEHSLDRKKLNYLEWDSKYH---------------------- 170

Query: 179 ESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEV 238
             I+  PL NW  + I + +    +   PLY                             
Sbjct: 171 -LIKYHPLYNWKLEVIEKMVKKHKVPYNPLYDKG-------------------------- 203

Query: 239 IKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSME 294
                  F ++GC P T +V+                  S R GR    D +   E
Sbjct: 204 -------FLSIGCAPCTRSVK---------------CGESYRSGRWWWEDDSIKKE 237


>UniRef50_A1WA11 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase n=6
           Tax=Proteobacteria RepID=A1WA11_ACISJ
          Length = 391

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 48/316 (15%), Positives = 85/316 (26%), Gaps = 51/316 (16%)

Query: 17  IHIIREVAAEFS------NPVMLYSIGKDSSVMLHLARKAFYPGTLP-----FPLLHVDT 65
             ++R V AE+         ++ +S GKDS+V+     +A              ++  DT
Sbjct: 26  EEVVRAVRAEYLSETQAYPWIIGFSGGKDSTVVSQAVFEALLQVPPSQRKRHIHVVSNDT 85

Query: 66  GWKFREMYEF-------RDRTAKAYGCELLVHKNPEG---------VAMGINPFVHGSAK 109
             +   +               +     + V               +  G          
Sbjct: 86  QVESPLVMSHLVKVQTAIREMTQTLRLPVDVVTTRPEPDKTFWTLLIGKGYPSPNQTMRW 145

Query: 110 HTDIMKTEGLKQAL----NKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRP 165
            TD +K     + +    +++G      G R DE  SR             R      R 
Sbjct: 146 CTDRLKILPTSRYILDNVSEHGAAIVILGVRLDESDSR-------------RNSINKFRN 192

Query: 166 ELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMM 225
               N         +    P+ N T  D+W+ +                  L +      
Sbjct: 193 LEGSNLTPHTELPGAFIYRPIVNLTIDDVWEVLGQCQPP-----WGGTHRDLIQLYRDAE 247

Query: 226 IDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE-RQGRV 284
             +  + L   E         R  GCW  T   +  +        +   S   E RQ   
Sbjct: 248 GGECPVVLSKDEAPGCGTANSR-FGCWTCTVVEKDKSLQGFVDSGKHEFSALIEFRQWLR 306

Query: 285 IDRDQAGSMELKKRQG 300
             R+      +++R G
Sbjct: 307 DIRNDPRYRSIERRNG 322


>UniRef50_B8KW50 Phosphoadenosine phosphosulfate reductase n=1 Tax=gamma
           proteobacterium NOR51-B RepID=B8KW50_9GAMM
          Length = 228

 Score =  119 bits (298), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 41/216 (18%), Positives = 68/216 (31%), Gaps = 36/216 (16%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
           EA    I+    +     +   S G +++  LH    A        P++ VDTG+  R+ 
Sbjct: 34  EATPAEIVTWALSLDKRAIATTSFGVNAAATLH----AVVEQAPSLPVIWVDTGFNLRDT 89

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVAM------GINPFVH--GSAKHTDIMKTEGLKQALN 124
           Y   D   +  G  L V+              GI            T+ +K E  ++A+ 
Sbjct: 90  YVQADAVTEQLGLNLHVYSPLITAERISAKLGGIPLPEDADNHRWFTEKVKLEPFRRAIA 149

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
            +     F G R +E   R    I S   R                          I+V 
Sbjct: 150 DFRPQLWFSGIRAEETDHRRSLDIVSLDHR------------------------GIIKVA 185

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
           P   W++ +I  Y+    +     Y    +    R+
Sbjct: 186 PFFYWSDSEIDSYMLEHGLVSCQHYFDPTKVSSGRE 221


>UniRef50_C0RZY2 FAD synthetase n=3 Tax=Paracoccidioides brasiliensis
           RepID=C0RZY2_PARBP
          Length = 347

 Score =  119 bits (297), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 51/300 (17%), Positives = 87/300 (29%), Gaps = 81/300 (27%)

Query: 6   LTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGT-------- 55
           L  ++     S+ +I+E    FS  +  + Y+ GKD  VML L   + +P          
Sbjct: 106 LHRVQNRTCTSLRVIQEALHRFSLQDLSLSYNGGKDCLVMLILFLASLHPFPAATKTATS 165

Query: 56  ------------LPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPF 103
                          P ++      FR + +F   ++ AY   L+ +           P 
Sbjct: 166 DNRKKSSTSSPPSTIPAIYAQPHHPFRSVEDFVASSSHAYHLSLVCYTTNP-------PH 218

Query: 104 VHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQ 163
               +  T  +               A F G RR +                        
Sbjct: 219 ATIRSAFTSYLSLHP--------QIRAIFVGTRRTD----------------------PH 248

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
             +L H         + +R+ P+ +W   +IW +I    I+  PLY      +   +   
Sbjct: 249 GEKLTHFDRTDHGWPDFMRIHPVIDWHYAEIWAFIRHLGIEYCPLYDEGYTSLGGMNDTH 308

Query: 224 MMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGR 283
                   D Q  +  + R  R+R                         L+    ER GR
Sbjct: 309 PNPKLQIRD-QDSDDDQHRKARYR---------------------PAYELMDDEEERLGR 346


>UniRef50_B9Q2H9 Cancer-associated gene protein, putative n=2 Tax=Eukaryota
           RepID=B9Q2H9_TOXGO
          Length = 575

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 59/316 (18%), Positives = 95/316 (30%), Gaps = 38/316 (12%)

Query: 1   MDQIRLTHLRQLEAESIHIIRE--VAAEFSNPVMLYSIGKDSSVMLHLAR--KAFYPGTL 56
           +   R   +R  E +    IR   +        +  S GKDS+V+LH+     A     L
Sbjct: 85  LRSCRECFVRAFEDDVSAFIRRFSLFQRGQKVAVCVSGGKDSAVLLHVLHTLNARENLGL 144

Query: 57  PFPLLHVDTGWK--FREMYEFRDRTAKAYGCELLVHK--------NPEGVAMGINPFVHG 106
              LL VD G K           R ++ Y   L V            + +A        G
Sbjct: 145 SLHLLAVDEGIKGYRDHALAAVRRNSEVYNLPLHVVSYASLYHGWTMDRIAQQALLGKDG 204

Query: 107 SAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPE 166
                 I + +  ++     G D    G   D+        I              + P 
Sbjct: 205 DCTFCGIFRRQAFERGAQDIGADVLCTGHNADDGAETFLMNILRGD--------MQRLPV 256

Query: 167 LWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI 226
                 G       +RV PL    ++++  Y     +D                G++   
Sbjct: 257 SGAPLTGSREGPSVMRVKPLLASYQREVVLYAHFNRLDY--FATECTYSGAAYRGLVRNF 314

Query: 227 DDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE--RQGRV 284
             +  D Q  + +   +   R L  W  +      A            +  SE  R+GR 
Sbjct: 315 LSSLQDNQHQQRVLDLLHAARKL--WVPSRVSSEAA----------KDAGDSEARREGRS 362

Query: 285 IDRDQAGSMELKKRQG 300
            D D AG  +  +R+G
Sbjct: 363 GDSDMAGRTQSVRRKG 378


>UniRef50_Q97JS3 Similar to phospho-adenylylsulfate sulfotransferase n=1
           Tax=Clostridium acetobutylicum RepID=Q97JS3_CLOAB
          Length = 454

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 58/292 (19%), Positives = 94/292 (32%), Gaps = 42/292 (14%)

Query: 3   QIRLTHLRQLEA----ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPG--TL 56
            +    L  LE     +S+  I++    +    + +S GKDS V+ ++      P     
Sbjct: 87  SLNKNRLIFLENRSVSKSLKFIKKY--RYHEKRLAHSGGKDSDVLFYIFVNKILPLLKNK 144

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGIN------PFVHGSAKH 110
            + +   +T     + Y            +L +H   +G+   I            +   
Sbjct: 145 DYKIDFNNTTNDTAQTYLHIKELP---NDKLNIHNPQKGIIEWITEDKNYFLPCVTNRNC 201

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
               K   +K  L+K        G RRDE   R+K       D       KN  PE W  
Sbjct: 202 CSNYKEGRMKDYLDKDKKYLLILGMRRDESPDRSKYDY----DLNKSMGEKNNVPENWK- 256

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMI-DDN 229
                      R  P+  WT+ DIW YI + NI +  +Y         R G L+     +
Sbjct: 257 -----------RFLPILEWTDIDIWLYILMNNIKVNHMYKLGYN----RCGCLICPFQSD 301

Query: 230 RIDLQPGEVIKKRMVRFRTL---GCWPLTGAVESNAQTLPEIIEEMLVSTTS 278
            IDL        +  R+  +             +   +L E +E       S
Sbjct: 302 YIDLLTQYFYPFQWSRWMKIVEKNYEVC-SVGSNLKWSLKEWLEGRWKQGKS 352


>UniRef50_B6QDU1 FAD synthetase, putative n=1 Tax=Penicillium marneffei ATCC 18224
           RepID=B6QDU1_PENMQ
          Length = 272

 Score =  119 bits (297), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 40/247 (16%), Positives = 75/247 (30%), Gaps = 51/247 (20%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPG----- 54
           D   L +L++    S+ +I +   ++      + Y+ GKD  V+L L             
Sbjct: 50  DDELLQNLQKQIRISMKVIEDSFQQYRPQELSLSYNGGKDCLVLLVLILACLPSSLPTDS 109

Query: 55  --TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTD 112
                   + +     F E+YEF   ++K Y  +L  ++ P   A+ +            
Sbjct: 110 GFPKTLQSIFIIPYKSFPEVYEFVQTSSKDYFLDLTRYELPMRAALEVY----------- 158

Query: 113 IMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYN 172
            +K              A + G RR +                           L H   
Sbjct: 159 -LKDRP--------NIKAIWIGTRRVD----------------------PNGGLLKHFDP 187

Query: 173 GQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
              +  + +R+ P+ +W   +IW +I    +D  PLY      +   +            
Sbjct: 188 TDKDWPQFMRIHPVIDWHYAEIWAFIRHLGLDYCPLYDRGYTSLGGVNDTFPNPALAIPG 247

Query: 233 LQPGEVI 239
            Q     
Sbjct: 248 DQSKFRP 254


>UniRef50_A3RYW5 Co-activator of prophage gene expression IbrA n=10
           Tax=Proteobacteria RepID=A3RYW5_RALSO
          Length = 416

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 45/270 (16%), Positives = 80/270 (29%), Gaps = 38/270 (14%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTL-PFPLLHVDTGWKFREM 72
             +   +R V A+F+   + +S GKDSSV LHLA +        P     +D   ++R  
Sbjct: 12  EAAKARLRLVFAQFAQVCVAFSGGKDSSVTLHLALEVAREMGRGPVHAFFIDLEGQYRAT 71

Query: 73  YEFRDRTAKAYG-------CELLVHKNPEGVAMGINPFVHGSA-KHTDIMKTEG------ 118
            +        +          + +      +      +  G        + T        
Sbjct: 72  IDHVTEMLSRHDVRPWWVCLPINLRNASSALEPFWCAWEPGREADWIRPLPTHPSVISDP 131

Query: 119 ------------------LKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP 160
                                 L +    A   G R DE  +R          +   W P
Sbjct: 132 DHFPFYRFRMEFEAFVPAFNAWLARDTPTAILVGIRSDESLNRYLAVKRRATIKKCAWTP 191

Query: 161 KN-QRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLER 219
               RP  W        +  ++  FP+ +W  +D+W+Y+    +    LY    R  +  
Sbjct: 192 PGADRPIAWSAR--DHARSRAVTFFPIYDWRFEDLWRYVAERGLAYNRLYDQMYRAGVAC 249

Query: 220 DGMLMM--IDDNRIDLQPGEVIKKRMVRFR 247
             M +     D++          +    FR
Sbjct: 250 SQMRICQPYGDDQRKGLDLYHRIEPGTWFR 279


>UniRef50_C5K7J4 FAD synthetase, putative n=1 Tax=Perkinsus marinus ATCC 50983
           RepID=C5K7J4_9ALVE
          Length = 308

 Score =  118 bits (296), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 44/240 (18%), Positives = 79/240 (32%), Gaps = 57/240 (23%)

Query: 6   LTHLRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYP---GTLPFPL 60
           +  +RQ  A+S+ II E    +      + ++ GKD +V+LH+    F       +P   
Sbjct: 89  INRVRQQTAKSLSIIAEAYDNYKPEELCLAFNGGKDCTVLLHMVDHVFRQKHSEGVPLRT 148

Query: 61  LHV-----DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMK 115
           L++     DT   F E+  F +   K Y  +++       V                   
Sbjct: 149 LYIADPKNDT---FEEVESFIEDMQKVYNLDIMRVVGGVKVG------------------ 187

Query: 116 TEGLKQALNKY-GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
              L++   ++    A F G+R  +                          +L       
Sbjct: 188 ---LERIKEEHPELKAIFMGSRSTD----------------------PFCGDLTAFAKTT 222

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
               E +RV P+ +WT  D+W Y+ L  +    LY      +  +   +   D    D  
Sbjct: 223 EGWPEFMRVNPILDWTYSDVWNYLELYGVKYCKLYGHGYTSIGRKSDTIPNPDLAMRDGD 282


>UniRef50_C7TXS2 RFad1, flavin adenine dinucleotide synthetase, homolog n=1
           Tax=Schistosoma japonicum RepID=C7TXS2_SCHJA
          Length = 509

 Score =  118 bits (295), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 37/235 (15%), Positives = 77/235 (32%), Gaps = 23/235 (9%)

Query: 9   LRQLEAESIHIIREVAAEFSN--PVMLYSIGKDSSVMLHLARKAFYPGTLP--------- 57
           L +  AES+ II E   ++S+   V+ ++ GKD +V+LHL                    
Sbjct: 254 LSKRVAESVQIIEEALDKYSHSELVICFNGGKDCTVLLHLVHAVVQHLNNSNQESRKPTK 313

Query: 58  -FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
              LL++ +   F E+  F ++T      ++    + E +   +  +             
Sbjct: 314 LPKLLYIRSHSTFPEIEIFVEKT-----VDVYYSSSNEILRPDLEKYEQKQTSVNSQ--- 365

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
                  +K      + G+ +   ++   +                   ++ H       
Sbjct: 366 ---SSLCSKESGVVIYEGSIKSILENFLHDNPEIKGAFMGTRYTDPGARKMSHMMMSDPG 422

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRI 231
             + +R+ PL  WT  D+W ++   +I    LY      +   +          I
Sbjct: 423 WPQILRINPLLEWTYSDVWDFLRSLSIPYCSLYDVGYTSIGSLEDTHPNPQLRYI 477


>UniRef50_Q0VNW4 Phosphoadenosine phosphosulfate reductase n=5 Tax=Proteobacteria
           RepID=Q0VNW4_ALCBS
          Length = 236

 Score =  118 bits (295), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 30/211 (14%), Positives = 65/211 (30%), Gaps = 36/211 (17%)

Query: 18  HIIREVAAEF--SNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEF 75
             IR V  +F     ++  S    S+  LH+        +    +  +DTG+ F +  ++
Sbjct: 36  ERIRRVYEDFAPDRIMVTSSFAATSAYFLHIISTIRPQQS----VHFIDTGYHFADTLKY 91

Query: 76  RDRTAKAYGCELLVHKNPEG---VAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAF 132
           +D   + +G  ++          V+     +         + K   L++A  K  +D   
Sbjct: 92  KDYLIERFGLNVVDVTPDPDHHQVSQENRMWETDPDLCCQVNKVNPLEEA--KENYDLWI 149

Query: 133 GGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQ 192
                 + + RA   ++  R                            I+  P+ + T++
Sbjct: 150 SSLMGWQTEHRAGLEVFEERR-------------------------GMIKFNPMIDVTKE 184

Query: 193 DIWQYIWLENIDIVPLYLAAERPVLERDGML 223
               YI   ++   PL       +       
Sbjct: 185 QRDAYIKEHDLPFHPLVAQGFDSIGCSHCTF 215


>UniRef50_Q22017 FAD synthetase region n=3 Tax=Caenorhabditis RepID=FLAD1_CAEEL
          Length = 519

 Score =  118 bits (295), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 45/241 (18%), Positives = 73/241 (30%), Gaps = 46/241 (19%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEF--SNPVMLYSIGKDSSVMLHLAR-KAFYPGTL--P 57
                   Q   E+  I+ E+  ++      + ++ GKD +V+LHL R K         P
Sbjct: 300 SENQIEFIQKLNEAESIVEEIVEKYPLEQIALSFNGGKDCTVLLHLLRLKVDEKYGPSTP 359

Query: 58  FPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTE 117
               H+    +F E  +F    AK Y  ++L    P                    +KT 
Sbjct: 360 IQGFHIMVEDQFPEATQFIIDAAKFYNIQVLEFPGP--------------------LKTG 399

Query: 118 GLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINK 177
               AL K                SRA +    +      W                 + 
Sbjct: 400 LA--ALKKTRPSIIPV-----LMGSRATDPNGKYMKTPVEW--------------TDSDW 438

Query: 178 GESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGE 237
            + +RV P+ NWT  D+W  +    +    LY      +  RD  +       +     E
Sbjct: 439 PQVLRVCPILNWTYTDVWHMLRGLCVPYCKLYDQGYTSLGGRDNTVKHPALRIVSSDGRE 498

Query: 238 V 238
            
Sbjct: 499 H 499


>UniRef50_Q04PC4 Phosphoadenylyl-sulfate reductase n=10 Tax=Bacteria
           RepID=Q04PC4_LEPBJ
          Length = 245

 Score =  117 bits (294), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 46/291 (15%), Positives = 79/291 (27%), Gaps = 92/291 (31%)

Query: 10  RQLEAE----SIHI-IREVAAEFS-NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHV 63
           ++LE +    S+   +  +  E+        S+G +  V+ H      +   L   +  +
Sbjct: 4   QELEQKLAPLSLEDSLEWINNEYGETAAFSTSLGLEDQVITH----VIFSRNLKIRIFTL 59

Query: 64  DTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGI---------NPFVHGSAKHTDIM 114
           DTG  F E Y+    T  +Y   +  +         +            V    +   I 
Sbjct: 60  DTGRLFNETYDLHKLTNASYNKRIETYFPDTAAVQNLINTKGPDSFYDSVDNRKECCYIR 119

Query: 115 KTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQ 174
           K E L +AL   G      G R ++  SR       F                       
Sbjct: 120 KVEPLNRAL--VGTKLWITGIRSEQSDSRHSLAKVEFDSSR------------------- 158

Query: 175 INKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
                 ++  PL +W+ + I  +I    +    L+                         
Sbjct: 159 ----NILKYHPLLDWSLERIQDFIDTYRVPTNVLHKKG---------------------- 192

Query: 235 PGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVI 285
                      F ++GC P T AV+                    R GR  
Sbjct: 193 -----------FPSIGCAPCTRAVQP---------------GEDIRAGRWW 217


>UniRef50_B4D6P5 Phosphoadenylyl-sulfate reductase (Thioredoxin) n=2 Tax=Bacteria
           RepID=B4D6P5_9BACT
          Length = 221

 Score =  117 bits (293), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 37/230 (16%), Positives = 72/230 (31%), Gaps = 38/230 (16%)

Query: 2   DQIRLTHLRQLEAESIHIIREVAAE-FSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPL 60
           DQI   +    E   + I+R   A+     ++  +     +V+LHL  +         P+
Sbjct: 4   DQIAQANAELREKAPLDIVRWAIAQAGGRAIVSTNFRPYEAVILHLVTQV----QPNIPV 59

Query: 61  LHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAM-----GINPFVHGSA-----KH 110
           L VD G+     Y   +   K    ++         A      G  P             
Sbjct: 60  LWVDHGYNKPATYTHAEELKKLLNLDIRGFVPKMTAAHYDAVHGGAPEPTPENEERIKTF 119

Query: 111 TDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHN 170
           + +MK E  ++ + +          R+ +  +RA   I S    F               
Sbjct: 120 STVMKLEPFQRGMRELAPTVWITALRKVQNPNRAGLDIVSHDANFGSL------------ 167

Query: 171 YNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
                      +V P+  W ++D+  Y+   ++     Y    +   +R+
Sbjct: 168 -----------KVSPVFYWNDKDMHNYLTEHHLPNEWDYFDPAKADEKRE 206


>UniRef50_A6EMB0 Phosphoadenosine phosphosulfate reductase n=1 Tax=unidentified
           eubacterium SCB49 RepID=A6EMB0_9BACT
          Length = 191

 Score =  117 bits (293), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 43/212 (20%), Positives = 69/212 (32%), Gaps = 34/212 (16%)

Query: 15  ESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYE 74
           E   II+       NP++  S GK S+ ++H    A         +L  DTG+     YE
Sbjct: 2   EPEEIIQFALHLSKNPLLTTSFGKYSACLIH----AVSTVKKDIAVLWCDTGYNTDATYE 57

Query: 75  FRDRTAKAYGCELLVHKNPEGVAM----GINPFVHGSAKH--TDIMKTEGLKQALNKYGF 128
                +  Y   L V       A        P       H  ++I K    ++A+ K   
Sbjct: 58  HVSSLSSTYKLNLEVCSPQFTTAYINNKYGAPEFDNPNHHIISEITKVAPFQKAIKKIHP 117

Query: 129 DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSN 188
           D      R+D+   R    I S+ +                           ++V P  N
Sbjct: 118 DVWLTNLRKDQNPYRESLDILSYSEE------------------------GILKVAPFFN 153

Query: 189 WTEQDIWQYIWLENIDIVPLYLAAERPVLERD 220
           W++  I  Y+   N+ I   Y    +    R+
Sbjct: 154 WSDSQILSYMNKNNLPIHVDYFDPIKASQSRE 185


>UniRef50_D1PAG4 ATP synthase F0, A subunit n=1 Tax=Prevotella copri DSM 18205
           RepID=D1PAG4_9BACT
          Length = 188

 Score =  117 bits (293), Expect = 4e-25,   Method: Composition-based stats.
 Identities = 38/172 (22%), Positives = 59/172 (34%), Gaps = 34/172 (19%)

Query: 51  FYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGV------AMGINPFV 104
                    +  +DTG  F E Y+  D+T   YG  L V               GIN F 
Sbjct: 36  LVKIDKSARIFTLDTGRLFPETYQLIDKTNMTYGINLEVFFPNYEAVQQMVKEEGINLFY 95

Query: 105 ---HGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPK 161
                  +   + K E LK+A+   G D    G R+ +  +R   ++  + D        
Sbjct: 96  NSIESRHRCCQVRKLEPLKRAMQ--GLDVWICGLRKQQSVTRKDMQVVEWDD-------- 145

Query: 162 NQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAE 213
                              I+V PL NW+E+D+ QY+   ++    L     
Sbjct: 146 ---------------IHNLIKVNPLINWSEEDVEQYVKKHHVPYNKLQDKGY 182


>UniRef50_A9USG3 Predicted protein (Fragment) n=1 Tax=Monosiga brevicollis
           RepID=A9USG3_MONBE
          Length = 239

 Score =  117 bits (293), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 45/274 (16%), Positives = 85/274 (31%), Gaps = 49/274 (17%)

Query: 1   MDQIRLTHLRQLEAE--SIHIIREVAAE--FSNPVMLYSIGKDSSVMLHLARKAFYPGTL 56
           + Q +L  L    A+   + I+R + A+  + N V   S G    V+  +  +       
Sbjct: 3   LSQDKLAALNDQLADCSPVQILRWMRAQPAWGNVVQFTSFGVSGMVITDIMTRL----GF 58

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVA-------MGINPFVHGSAK 109
             P++ VDT + F E  + +    K Y  ++L +               G   +   S  
Sbjct: 59  LTPIVFVDTLYHFDETLDLKATVEKVYNRQVLAYGPQTSSDRSTFEEYYGQELWSKDSEF 118

Query: 110 HTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWH 169
           +  + K E   +AL +   D    G RR +  SRA   +                     
Sbjct: 119 YHYLTKVEPTGRALTELEVDVWITGRRRSQGSSRASLAVLE------------------- 159

Query: 170 NYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDN 229
                +     I++ P+++      W+Y+    +    L     + + +      +  D 
Sbjct: 160 -----VASDGRIKINPMAHVDWASTWKYVKSAGVPYNKLVDQGYKSIGDVHSTRPVGHD- 213

Query: 230 RIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQ 263
                  E   +    FRT             A 
Sbjct: 214 -----APERSGRWSGEFRT----ECGMHTAVKAA 238


>UniRef50_Q0RVM7 Probable phosphoadenylyl-sulfate reductase (Thioredoxin) n=3
           Tax=Rhodococcus RepID=Q0RVM7_RHOSR
          Length = 264

 Score =  117 bits (293), Expect = 5e-25,   Method: Composition-based stats.
 Identities = 51/251 (20%), Positives = 85/251 (33%), Gaps = 33/251 (13%)

Query: 13  EAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREM 72
            A+ +  I    A      + +S GKDS ++L LAR+         P++  D+G  + E 
Sbjct: 29  VADILTRIEAHLAAHDG-YVAFSGGKDSLIVLDLARRI----EPDVPVVFFDSGLDYPET 83

Query: 73  YEFRDRTAKAYGCELLVHKNPEGVA--------MGINPFVHGSAKHTDIMKTEGLKQALN 124
           Y++       +  +L        +            +  V       +++ TE  ++A  
Sbjct: 84  YDYLTELTHTWRLDLHRIPTDPPLLQVLADSGHWDHSAPVGTPLDLHEVLITEPARRAHQ 143

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
             G      G R DE  +R          R  R D    R +    Y             
Sbjct: 144 LLGP-GELWGVRADESAARRHL-----YTRGGRRDGIVTRADGTTAYG------------ 185

Query: 185 PLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMV 244
           P+ NWT  D+W +I    + I P+Y       +      +    +   L  G +   R  
Sbjct: 186 PIWNWTIIDVWAHIARHQLPINPVYAKLRELGVPEQQHRLSHLIDGSHLDRGRLTWLR-R 244

Query: 245 RFRTLGCWPLT 255
            + TL C  LT
Sbjct: 245 GWPTL-CEQLT 254


>UniRef50_A0Z1B4 Possible 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase n=1
           Tax=marine gamma proteobacterium HTCC2080
           RepID=A0Z1B4_9GAMM
          Length = 226

 Score =  116 bits (291), Expect = 8e-25,   Method: Composition-based stats.
 Identities = 40/203 (19%), Positives = 71/203 (34%), Gaps = 37/203 (18%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMY 73
           A    I+R   A+    V   S G  S+ MLHL  K         P++ +D+G+      
Sbjct: 25  ASPETIVRWALAQNLRVVTSTSFGTQSAAMLHLVSKL----GPSLPIIWIDSGFAPANTR 80

Query: 74  EFRDRTAKAYGCELLVHKNPEGVAM---------GINPFVHGSAKHTDIMKTEGLKQALN 124
           EF  +  +     L+ ++                  +      A+  +++K E  ++A++
Sbjct: 81  EFSRQLVEQLNLNLVTYRPNLTPLRCLHAISATDTEDLTEEQRAQLANLVKIEPFERAMS 140

Query: 125 KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVF 184
                    G R +E   RAK R  S+ DR                          +++ 
Sbjct: 141 ALKPHIWLTGIRAEETSFRAKLRPASWDDR------------------------GMLKLA 176

Query: 185 PLSNWTEQDIWQYIWLENIDIVP 207
           P  + +E DI  Y+   N+   P
Sbjct: 177 PFLHSSEADIDAYLAQHNLPRGP 199


>UniRef50_Q74M42 NEQ525 n=1 Tax=Nanoarchaeum equitans RepID=Q74M42_NANEQ
          Length = 352

 Score =  116 bits (290), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 43/226 (19%), Positives = 83/226 (36%), Gaps = 38/226 (16%)

Query: 8   HLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGW 67
            +++   E+I  I++   ++   V+ +S GKDS+ +  LA+KA     + F L+ VDTG 
Sbjct: 159 DIKEKVNEAIEFIKQ-FKDYE-IVIPFSGGKDSTTVAILAKKA----KVDFDLVFVDTGL 212

Query: 68  KFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYG 127
           +F++  E+ D  +K     + +          +  F +   +     K   L   +    
Sbjct: 213 EFKQTLEYIDYISKKIK-PINIVYAGIDKKYKMFGFDYLKRRLCTKDKITTLYNYVRNNY 271

Query: 128 FD-AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPL 186
            +     G R  E ++R                           +  +I K E +   P+
Sbjct: 272 ENPVLLVGDRLIESEAR--------------------------LFRPRIFKDEFLVAQPI 305

Query: 187 SNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRID 232
             ++  D    +  ENI + PLY         R G  +    +  +
Sbjct: 306 KFFSYADEQILLEKENIKLNPLYEKG----FYRVGCNVCPFLDNYE 347


>UniRef50_P77216 Uncharacterized protein ybdN n=243 Tax=Bacteria RepID=YBDN_ECOLI
          Length = 406

 Score =  115 bits (288), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 39/248 (15%), Positives = 65/248 (26%), Gaps = 42/248 (16%)

Query: 9   LRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWK 68
           L  LEA +   I           + +S GKDS +MLHL  +          +L +D   +
Sbjct: 10  LNILEA-ARERITWTLNTLPRVCVSFSGGKDSGLMLHLTAELARQMGKKICVLFIDWEAQ 68

Query: 69  FREMYEFRDRTAKAY----------GCELLVHKNPEGVAMGINPFVHGSAK--------- 109
           F     +     + Y             L    +          +               
Sbjct: 69  FSCTINYVQSLRELYTDVIEEFYWVALPLTTQNSLSQYQPEWQCWEPDVEWVRQPPQDAI 128

Query: 110 -----HTDIMKTEGLKQALNKY-------GFDAAFGGARRDEEKSRAKERIYSFRDRFHR 157
                          +Q + ++          A   G R DE  +R              
Sbjct: 129 TDPDFFCFYQPGMTFEQFVREFAEWFSQKRPAAMMIGIRADESYNRFVA----------I 178

Query: 158 WDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVL 217
                QR      +      G S  ++P+ +W   DIW +         PLY    +  +
Sbjct: 179 ASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTWYANHQSLCNPLYNLMYQAGV 238

Query: 218 ERDGMLMM 225
               M + 
Sbjct: 239 PLRHMRIC 246


>UniRef50_A8A8R5 Phosphoadenosine phosphosulfate reductase n=1 Tax=Ignicoccus
           hospitalis KIN4/I RepID=A8A8R5_IGNH4
          Length = 421

 Score =  115 bits (287), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 35/205 (17%), Positives = 74/205 (36%), Gaps = 32/205 (15%)

Query: 22  EVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAK 81
           +V       V+ +S GKDS+  L +A++A          ++VDTG       ++ +  ++
Sbjct: 218 KVLEGCERAVVPWSGGKDSTAALLIAKRACDE----VTAVYVDTGVDMYLNRKYVELWSQ 273

Query: 82  AYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEK 141
               +L++ + P    +          +    +K +GL++A+ +   D    G R  E +
Sbjct: 274 KLNVDLIIKEVPVKSQIFQRGLPTKEDRWCTALKLKGLEEAIREVKPDYIVVGDRDAESQ 333

Query: 142 SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLE 201
           +R+                          +  +  +G      PL  W+   +  Y++  
Sbjct: 334 ARSA------------------------RWEERAWEGVGTVKAPLKLWSAMMVQLYLFKN 369

Query: 202 NIDIVPLYLAAERPVLERDGMLMMI 226
            +   PLY +       R G  +  
Sbjct: 370 KVFPNPLYASG----FYRLGCYVCP 390


>UniRef50_A8H4Y9 Phosphoadenosine phosphosulfate reductase n=15
           Tax=Gammaproteobacteria RepID=A8H4Y9_SHEPA
          Length = 588

 Score =  115 bits (287), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 54/339 (15%), Positives = 99/339 (29%), Gaps = 73/339 (21%)

Query: 14  AESIHIIREVA-AEFSNPVMLYSIGKDSSVMLHLARKAF-----YPGTLPFPLLHVDTGW 67
              I  ++ V  ++    V+ YS GKDSS ++ L   A         T P  ++  DT  
Sbjct: 74  KHFIDDVQSVYCSDNRPWVIGYSGGKDSSAVVTLIYLALLSLDESKRTKPVYVVASDTLV 133

Query: 68  KFREMYEFRDRT-------AKAYGCELLVHK----NPEGVA-----MGINPFVHGSAKHT 111
           +   + +  +R+       AK  G  L  HK      +         G           T
Sbjct: 134 ETPLVVDHVNRSLESIGNNAKKDGLPLTTHKVLPKPHQTFWSCLLGKGYPAPTQSFRWCT 193

Query: 112 DIMKTEGLKQALN----KYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPEL 167
           + MK + +   +     ++       G+R  E  SRA+  + +     +    ++     
Sbjct: 194 ERMKIDPVSDFIKDKVSQHDEVIVILGSRSQESASRAQ--VIAKHKIENTRLARHTTLAN 251

Query: 168 WHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDI--------------------VP 207
              Y             P+  W+  D+W+ I   ++++                     P
Sbjct: 252 AFIYT------------PIDTWSMDDVWKLIRACSLEVTISPMGIGKKWADEYGLEWENP 299

Query: 208 LYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPE 267
                +   L               +           RF   GCW  T   +  A  +  
Sbjct: 300 --WGGKNLTLWNLYKDSSDQGECPMVIDDSTPSCGNSRF---GCWTCTVVTKDRA--MES 352

Query: 268 IIEEMLVSTTSERQGRVIDRD------QAGSMELKKRQG 300
           +I+            R    +      +      K+RQG
Sbjct: 353 LIQNGEEWMQPLLTFRNKLAETNVPANKDIYRNYKRRQG 391


>UniRef50_A2DE77 Phosphoadenosine phosphosulfate reductase family protein n=1
           Tax=Trichomonas vaginalis RepID=A2DE77_TRIVA
          Length = 227

 Score =  115 bits (287), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 34/230 (14%), Positives = 75/230 (32%), Gaps = 45/230 (19%)

Query: 9   LRQLEAESIHIIREVAAEFSN-PVMLYSIGKDSSVMLHLARKAFYPGTLPFPL--LHVDT 65
           L    A +  +++   A+      + ++ GKDSSV+L L R+      +  P+    +  
Sbjct: 19  LNGKIAITSKVLKLAYADHGPEIGLCFNGGKDSSVVLDLVRRFHESAKISTPVRPFFIKE 78

Query: 66  GWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNK 125
              F E+ EF  +T +  G  +   ++                          +++ + +
Sbjct: 79  KNDFPEITEFVKQTEERIGVTIRKVQSDSI--------------------KNAIEKIVEE 118

Query: 126 YGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
               + F G R+ +                           +        +   ++R+FP
Sbjct: 119 DRIYSFFLGQRKTD----------------------PNCSNIKEFNLTSDDWVHAMRIFP 156

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQP 235
           + NW  +DIW+YI    + +  LY      +      +        + + 
Sbjct: 157 ILNWAYKDIWEYIDALELPVCSLYSKGYTSIGNTKNTIPNPRLYNPNTKQ 206


>UniRef50_B5YMF1 Predicted protein (Fragment) n=1 Tax=Thalassiosira pseudonana
           CCMP1335 RepID=B5YMF1_THAPS
          Length = 277

 Score =  115 bits (287), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 36/225 (16%), Positives = 71/225 (31%), Gaps = 47/225 (20%)

Query: 29  NPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEF---RDRTAKAYGC 85
             V + S G    V+LHL  +         P++ +DT   F+E YEF     +++K  G 
Sbjct: 48  PMVQVTSFGPSGLVVLHLLSQL--HMLNDVPVVTLDTLHLFKESYEFYDTVQQSSKFNGM 105

Query: 86  ELLVHKN----------------PEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFD 129
           EL + K                       G   +     ++  + K + L++  N +   
Sbjct: 106 ELTITKPIRRDDDGDETEIQTRQEFDEIYGAELWKTEPEQYVQLTKQKPLEKLTNSWHVK 165

Query: 130 AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNW 189
               G RR +   R   ++  F                              ++ PL+  
Sbjct: 166 MWITGRRRSQGGERTNLKVLEFART--------------------------WKLNPLAYL 199

Query: 190 TEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQ 234
           +   +W++I   N+    LY      + +     +    +    +
Sbjct: 200 SYSQVWEHIRHYNLPYNSLYDKGYTSLGDEMTTDLPTGSDERSGR 244


>UniRef50_B9ZQQ7 Phosphoadenosine phosphosulfate reductase n=1 Tax=Thioalkalivibrio
           sp. K90mix RepID=B9ZQQ7_9GAMM
          Length = 799

 Score =  114 bits (286), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 48/324 (14%), Positives = 88/324 (27%), Gaps = 47/324 (14%)

Query: 11  QLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGT------LPFPLLHVD 64
            L A ++   R++ A+        S GKDS+  L+L  +A            P  +LH D
Sbjct: 5   ALRAHALDQFRDLFAKNEVLAFATSFGKDSTASLNLGLEAAIAHRQAGGDVPPILVLHTD 64

Query: 65  TGWKFR-------EMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFV-----------HG 106
           T  +          M E  +  A A+G ++ V  +   +       V             
Sbjct: 65  TTVENPAVRVYADRMIEHVETFAAAHGLDVRVKVSKPSLLSQWPVHVVSGRRLPTFANRA 124

Query: 107 SAKHTDIMKTEGLKQALN----------KYGFDAAFGGARRDEEKSRAKERIYSFRDRFH 156
             + +   K    ++ L                    G R DE   RA            
Sbjct: 125 HRRCSVEYKRSPAERTLKVAQGVLEAEGHDRMPVVVLGTRMDESAGRA-----------I 173

Query: 157 RWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPV 216
           R   + +   +    +       +    PL++W+  D+W Y+     D    Y       
Sbjct: 174 RMTRRGEGAHVNETRDPDTGTVTARSFAPLADWSTDDVWAYLADAGRDH--AYPGFAPDF 231

Query: 217 LERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST 276
            +   +        + +                GCW  T +  S+      + +      
Sbjct: 232 TDTIELYRDSAGECVIVNAVASSTPAAACGARHGCWACTVSGSSDKSMETLLAQPQYAYM 291

Query: 277 TSERQGRVIDRDQAGSMELKKRQG 300
                 R            ++  G
Sbjct: 292 QGLNDLRNWLVATQHDFSKRRWIG 315


>UniRef50_UPI0000D574FF PREDICTED: similar to RFad1, flavin adenine dinucleotide
           synthetase, homolog (yeast) n=1 Tax=Tribolium castaneum
           RepID=UPI0000D574FF
          Length = 455

 Score =  114 bits (284), Expect = 6e-24,   Method: Composition-based stats.
 Identities = 49/231 (21%), Positives = 75/231 (32%), Gaps = 50/231 (21%)

Query: 13  EAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLA----RKAFYPGTLPFPLLHVDTG 66
              +I  I E   ++   N  + ++ GKD +V+LHL     +K F   + P P L+V + 
Sbjct: 245 IKHAIENIEECLQQYGLENIFVSFNGGKDCTVLLHLVLTVVKKKFPQHSQPIPCLYVQSE 304

Query: 67  WKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY 126
             F E  EF D     Y  +++V                           + L Q L KY
Sbjct: 305 SPFPEQDEFIDLCKCYYNLKIMVINAGI---------------------KDALGQILEKY 343

Query: 127 -GFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFP 185
             F A F G RR +  S                       +L        N  + +RV P
Sbjct: 344 PNFKACFMGTRRTDPYS----------------------GDLTVFQMTDSNWPQILRVSP 381

Query: 186 LSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
           + +W   DIW Y+    +    LY      +               +L   
Sbjct: 382 VLDWHYSDIWDYLLFYKVPYCKLYDLGFTSLGNTVNTKRNPSLKCYELFDE 432


>UniRef50_A0DD33 Chromosome undetermined scaffold_46, whole genome shotgun sequence
           n=1 Tax=Paramecium tetraurelia RepID=A0DD33_PARTE
          Length = 205

 Score =  113 bits (283), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 45/251 (17%), Positives = 83/251 (33%), Gaps = 51/251 (20%)

Query: 1   MDQIRLTHLRQLEAESIHIIREVAA--EFSNPVMLYSIGKDSSVMLHLARKAFYPGTL-- 56
           MD         L  E+I  + ++    +F    + ++ GKD++V+L+LA+ A     +  
Sbjct: 1   MDNQNSQPSTILFQEAIDFLVKIFQIFKFPQIKICFNGGKDATVVLYLAKMALEKLQISR 60

Query: 57  PFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKT 116
               ++      F E+ EF ++  KA   +++                            
Sbjct: 61  EIECIYFKEKQPFPEIIEFMEQQKKALNLQIVE---------------------CKGCVK 99

Query: 117 EGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQIN 176
           E L+   N+    A   G RR +        + S                         N
Sbjct: 100 ENLQ---NQVQLQAVIMGTRRSD-PHGKTLNLISI---------------------TDNN 134

Query: 177 KGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPG 236
               +R+ P+  W    IW++I   NI    LY      + E  G      + +I ++P 
Sbjct: 135 YPSLLRINPILEWNYSQIWEFIRTFNIPYCSLYDQGYMCLGE-VGKTQPDKNYKIGMKPW 193

Query: 237 EVIKKRMVRFR 247
           E   +   + R
Sbjct: 194 EFDPQFERQNR 204


>UniRef50_C5PEQ4 Phosphoadenosine phosphosulfate reductase domain containing protein
           n=3 Tax=Onygenales RepID=C5PEQ4_COCP7
          Length = 352

 Score =  113 bits (283), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 52/323 (16%), Positives = 85/323 (26%), Gaps = 98/323 (30%)

Query: 6   LTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPGTLP------ 57
           L  ++Q    S+ ++RE  + +      + Y+ GKD  V+L L   + +P   P      
Sbjct: 84  LYRVQQQTRISLSVVREALSRYKLHELSLSYNGGKDCLVLLILFLSSLHPLPEPSSTKQK 143

Query: 58  -----------------------------------FPLLHVDTGWKFREMYEFRDRTAKA 82
                                               P ++      F  +  F D ++  
Sbjct: 144 TQAQQCTFKDKPEAPKSQNANPNLLDDPDDEPPTSIPAMYARPSHPFPSVETFVDSSSLT 203

Query: 83  YGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKY-GFDAAFGGARRDEEK 141
           Y   L  +              H + + T           L KY G  A F G RR +  
Sbjct: 204 YHLSLTRYTTD---------PPHTTLRDTFAC-------YLQKYPGIKAIFVGTRRTD-- 245

Query: 142 SRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLE 201
                                   +L H         + +R+ P+ +W   +IW +I   
Sbjct: 246 --------------------PHGEKLTHFDRTDHGWPDFMRIHPVIDWHYVEIWAFIRHL 285

Query: 202 NIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESN 261
            ++  PLY      +   +              P E  K       T             
Sbjct: 286 GVEYCPLYDQGYTSLGGTNDTHPNPKLQINKASPMEASKPSNAGQET------------- 332

Query: 262 AQTLPEIIEEMLVSTTSERQGRV 284
                      LV    ER GR 
Sbjct: 333 ---PKFRPAYELVEDEEERLGRY 352


>UniRef50_Q54RS3 Putative uncharacterized protein n=1 Tax=Dictyostelium discoideum
           RepID=Q54RS3_DICDI
          Length = 300

 Score =  113 bits (282), Expect = 9e-24,   Method: Composition-based stats.
 Identities = 42/274 (15%), Positives = 70/274 (25%), Gaps = 76/274 (27%)

Query: 3   QIRLTHLRQLEAESIHIIREVAAEFS--NPVMLYSIGKDSSVMLHLARKAFYPG------ 54
           +I          ESI  I     +F      + ++ GKD  V+LHL              
Sbjct: 32  KINKEEFYNKIMESIETIECAFNKFEFQEIALSFNGGKDCCVLLHLINYVLLKKFKNTIN 91

Query: 55  --------------------------TLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELL 88
                                           ++  T   F ++ EF +  +  Y   LL
Sbjct: 92  NSCNNNNNINNNNNKNNNNNNQINNKRNGLKTIYFQTPDSFNQVNEFTETCSSIYNLNLL 151

Query: 89  VHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERI 148
              +  G+  G                   L++ +      A F G R  +         
Sbjct: 152 EVSS-IGIKEG-------------------LEKIITSENIKAVFIGIRFGD--------- 182

Query: 149 YSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPL 208
                             L             +RV P+ NW   +IW++I + NI    L
Sbjct: 183 -------------PNSLHLEKFSYTDPGWPHFLRVNPILNWNYHEIWEFIKICNIPYCEL 229

Query: 209 YLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKR 242
           Y      + ++   +   D              R
Sbjct: 230 YDQGYTSIGQQHDTIPNPDLLIPSTLDQYYHANR 263


>UniRef50_Q11FT5 Phosphoadenosine phosphosulfate reductase n=1 Tax=Chelativorans sp.
           BNC1 RepID=Q11FT5_MESSB
          Length = 335

 Score =  112 bits (281), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 40/294 (13%), Positives = 79/294 (26%), Gaps = 47/294 (15%)

Query: 29  NPVMLYSIGKDSSVMLHLARKAFYPGT---LPFPLLHVDTGWKFREMYEFRDRTAKAYGC 85
           N V+ +S GKDS+  L +   A+       L   +++ DTG +   +  +     +    
Sbjct: 11  NWVVAFSGGKDSTAALKVLLAAYRHSGLQALNLTVIYCDTGVENPVLDLYVKSALERISE 70

Query: 86  ELLVHKNPEG----------------VAMGINPFVHGSAKHTDIMKTEGLKQALNKYGF- 128
           EL                        +  G  P  +     T  ++   +   +      
Sbjct: 71  ELKELGPTFKTQILKAPVQDRYFVRVIGRGYPPPTNSFRWCTTGLRIRPVSHFIEAQNPK 130

Query: 129 -DAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLS 187
                 G RR E + R +           RW  + +  + +                P+ 
Sbjct: 131 NTVVVLGLRRSESQQRDRTL---NDAPGGRWQKQREGNKDYDL------------FLPIL 175

Query: 188 NWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFR 247
           +    ++W  I+  +                   +          ++  +       RF 
Sbjct: 176 DLGVPEVWDTIFWLSKPR-------SIDPTALQDLYRDASGECPVIRAPQAPPCASGRF- 227

Query: 248 TLGCWPLTGAVESNAQTLPEIIEEMLVSTTSE-RQGRVIDRDQAGSMELKKRQG 300
             GCW  T   +  +           +    E R      R+       K+R G
Sbjct: 228 --GCWTCTVVRQDRSAKKLIEAGYSKLQPYFEFRAWLSEIRNDPVMRWPKRRNG 279


>UniRef50_B7J801 Conserved domain protein n=1 Tax=Acidithiobacillus ferrooxidans
           ATCC 23270 RepID=B7J801_ACIF2
          Length = 574

 Score =  112 bits (281), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 43/281 (15%), Positives = 81/281 (28%), Gaps = 48/281 (17%)

Query: 14  AESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYP-------GTLPFPLLHVDTG 66
            ++I  ++ +  +     + +S GKDSSV+L+L  +A             P  + H DTG
Sbjct: 3   KDAISSMQRLLCD-RPVSVAWSGGKDSSVVLNLTMQAAKAVLESGQTIAAPILVTHGDTG 61

Query: 67  WKFREMYEFR-------DRTAKAYGCELLVHKNPEGVAMGINP----------FVHGSAK 109
            +  E+  +         R A+ +   L VH     +                F   +  
Sbjct: 62  IENPEIRAYASTEIGRLRRYAERHRIPLAVHVATPNLTESWPLRVIGGRALPSFPGMNHD 121

Query: 110 HTDIMKTEGLKQALNKYGFD------AAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQ 163
            T  +K   +++   +              G R +E   RA   +         W     
Sbjct: 122 CTTDLKIHPMQRLRKRLQNPKTAASLVTIIGTRFEESPQRAARMLEREETADKPWL---- 177

Query: 164 RPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGML 223
                              + P++ WT +++W+Y+     D  P  L   R         
Sbjct: 178 ------------GDDNQWYLSPIAYWTMEEVWEYLGQCR-DGNPDVLTFSRFEEVFRIYA 224

Query: 224 MMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQT 264
                +   +       +        GC   T      +  
Sbjct: 225 DAAGSSCAVVGDMATKGQAKPCGARTGCAVCTPIGRDKSLE 265


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.312    0.123    0.340 

Lambda     K      H
   0.267   0.0376    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,577,791,980
Number of Sequences: 3077464
Number of extensions: 55204387
Number of successful extensions: 183669
Number of sequences better than 1.0e-01: 250
Number of HSP's better than  0.1 without gapping: 857
Number of HSP's successfully gapped in prelim test: 1359
Number of HSP's that attempted gapping in prelim test: 179335
Number of HSP's gapped (non-prelim): 2748
length of query: 302
length of database: 1,040,396,356
effective HSP length: 128
effective length of query: 174
effective length of database: 646,480,964
effective search space: 112487687736
effective search space used: 112487687736
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 92 (40.2 bits)
