Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	F	S	V	Q	E	T	L	F	S	L	L	Q	H	N	A	I	S	G	H	E	N	A	V	A	D	V	M	L	C	E	F	R	R	Q	A	K	E	V	W	R	D	R	L	G	N	V	V	A	R	Y	G	S	D	K	P	D	A	L
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	L	M	I	F	A	H	M	D	E	V	G	F	M	V	R	K	I	E	P	S	G	F	L	R	F	E	R	V	G	G	P	A	Q	V	T	M	A	G	S	I	V	T	L	T	G	D	K	G	P	V	M	G	C	I	G	I	K	S	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	F	A	K	G	D	E	R	T	Q	S	P	S	V	D	K	L	W	I	D	I	G	A	K	D	K	D	D	A	I	R	M	G	I	Q	V	G	T	P	V	T	L	Y	N	P	P	Q	L	L	A	N	D	L	V	C	S	K	A	L	D
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	R	L	G	C	T	A	L	L	G	V	A	D	A	I	S	T	M	E	L	D	I	A	V	Y	L	V	A	S	V	Q	E	E	F	N	I	R	G	I	V	P	V	L	R	R	V	K	P	D	L	A	I	G	I	D	I	T	P	S	C
Secondary structure
SS confidence
Disorder																																										?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	T	P	D	L	H	D	Y	S	E	V	R	I	N	Q	G	V	G	I	T	C	L	N	Y	H	G	R	G	T	L	A	G	L	I	T	P	P	R	L	I	R	M	L	E	Q	T	A	L	E	H	N	I	P	V	Q	R	E	V	A	P
Secondary structure
SS confidence
Disorder								?	?																				?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	V	I	T	E	T	G	Y	I	Q	V	E	Q	D	G	I	P	C	A	S	L	S	I	P	C	R	Y	T	H	S	P	A	E	V	A	S	L	R	D	L	T	D	C	I	R	L	L	T	A	L	A	G	M	S	A	A	H	F	P	V
Secondary structure
SS confidence
Disorder																																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.
Sequence		E	P	D	S	G	T	T	Q	E	A	H	P	L
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1vhe chain A Region: 2 - 355 Aligned: 347 Modelled: 354 Confidence: 100.0% Identity: 28% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:aminopeptidase/glucanase homolog; PDBTitle: crystal structure of a aminopeptidase/glucanase homolog Phyre2 PDB 1ylo chain A Region: 7 - 355 Aligned: 331 Modelled: 341 Confidence: 100.0% Identity: 31% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein sf2450; PDBTitle: crystal structure of protein of unknown function (possible2 aminopeptidase) s2589 from shigella flexneri 2a str. 2457t Phyre2 PDB 3kl9 chain F Region: 4 - 355 Aligned: 326 Modelled: 338 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: F: PDB Molecule:glutamyl aminopeptidase; PDBTitle: crystal structure of pepa from streptococcus pneumoniae Phyre2 PDB 1y0y chain A Region: 3 - 356 Aligned: 331 Modelled: 351 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:frv operon protein frvx; PDBTitle: crystal structure of tetrahedral aminopeptidase from p. horikoshii in2 complex with amastatin Phyre2 PDB 2pe3 chain A Region: 7 - 356 Aligned: 321 Modelled: 335 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:354aa long hypothetical operon protein frv; PDBTitle: crystal structure of frv operon protein frvx (ph1821)from pyrococcus2 horikoshii ot3 Phyre2 PDB 3isx chain A Region: 4 - 351 Aligned: 330 Modelled: 338 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of endoglucanase (tm1050) from thermotoga2 maritima at 1.40 a resolution Phyre2 PDB 3gb0 chain A Region: 1 - 356 Aligned: 353 Modelled: 356 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: crystal structure of aminopeptidase pept (np_980509.1) from bacillus2 cereus atcc 10987 at 2.04 a resolution Phyre2 PDB 3rza chain A Region: 1 - 357 Aligned: 353 Modelled: 357 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:tripeptidase; PDBTitle: crystal structure of a tripeptidase (sav1512) from staphylococcus2 aureus subsp. aureus mu50 at 2.10 a resolution Phyre2 PDB 2cf4 chain A Region: 4 - 354 Aligned: 330 Modelled: 346 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:protein ph0519; PDBTitle: pyrococcus horikoshii tet1 peptidase can assemble into a2 tetrahedron or a large octahedral shell Phyre2 PDB 3pfo chain B Region: 4 - 354 Aligned: 349 Modelled: 351 Confidence: 100.0% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:putative acetylornithine deacetylase; PDBTitle: crystal structure of a putative acetylornithine deacetylase (rpa2325)2 from rhodopseudomonas palustris cga009 at 1.90 a resolution Phyre2 PDB 1cg2 chain D Region: 4 - 356 Aligned: 348 Modelled: 353 Confidence: 100.0% Identity: 15% PDB header:metallocarboxypeptidase Chain: D: PDB Molecule:carboxypeptidase g2; PDBTitle: carboxypeptidase g2 Phyre2 PDB 1vgy chain B Region: 5 - 354 Aligned: 347 Modelled: 350 Confidence: 100.0% Identity: 11% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of succinyl diaminopimelate desuccinylase Phyre2 PDB 1vho chain A Region: 3 - 354 Aligned: 311 Modelled: 322 Confidence: 100.0% Identity: 26% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of a putative peptidase/endoglucanase Phyre2 PDB 1vix chain A Region: 1 - 357 Aligned: 353 Modelled: 356 Confidence: 100.0% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: crystal structure of a putative peptidase t Phyre2 PDB 3tx8 chain A Region: 1 - 353 Aligned: 345 Modelled: 352 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of a succinyl-diaminopimelate desuccinylase (arge)2 from corynebacterium glutamicum atcc 13032 at 2.97 a resolution Phyre2 PDB 3ife chain A Region: 4 - 355 Aligned: 348 Modelled: 352 Confidence: 100.0% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: 1.55 angstrom resolution crystal structure of peptidase t (pept-1)2 from bacillus anthracis str. 'ames ancestor'. Phyre2 PDB 2qyv chain B Region: 5 - 356 Aligned: 345 Modelled: 349 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: B: PDB Molecule:xaa-his dipeptidase; PDBTitle: crystal structure of putative xaa-his dipeptidase (yp_718209.1) from2 haemophilus somnus 129pt at 2.11 a resolution Phyre2 PDB 2pok chain B Region: 5 - 355 Aligned: 348 Modelled: 351 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m20/m25/m40 family; PDBTitle: crystal structure of a m20 family metallo peptidase from streptococcus2 pneumoniae Phyre2 PDB 3ic1 chain A Region: 1 - 355 Aligned: 348 Modelled: 355 Confidence: 100.0% Identity: 9% PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase2 from haemophilus influenzae Phyre2 PDB 2rb7 chain A Region: 4 - 356 Aligned: 339 Modelled: 353 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:peptidase, m20/m25/m40 family; PDBTitle: crystal structure of co-catalytic metallopeptidase (yp_387682.1) from2 desulfovibrio desulfuricans g20 at 1.60 a resolution Phyre2 1 c1vheA_ 2 c1yloA_ 3 c3kl9F_ 4 c1y0yA_ 5 c2pe3A_ 6 c3isxA_ 7 c3gb0A_ 8 c3rzaA_ 9 c2cf4A_ 10 c3pfoB_ 11 c1cg2D_ 12 c1vgyB_ 13 c1vhoA_ 14 c1vixA_ 15 c3tx8A_ 16 c3ifeA_ 17 c2qyvB_ 18 c2pokB_ 19 c3ic1A_ 20 c2rb7A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1vheA_ 100.0 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:aminopeptidase/glucanase homolog; PDBTitle: crystal structure of a aminopeptidase/glucanase homolog 2 c1yloA_ 100.0 31 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein sf2450; PDBTitle: crystal structure of protein of unknown function (possible2 aminopeptidase) s2589 from shigella flexneri 2a str. 2457t 3 c3kl9F_ 100.0 28 PDB header:hydrolase Chain: F: PDB Molecule:glutamyl aminopeptidase; PDBTitle: crystal structure of pepa from streptococcus pneumoniae 4 c1y0yA_ 100.0 33 PDB header:hydrolase Chain: A: PDB Molecule:frv operon protein frvx; PDBTitle: crystal structure of tetrahedral aminopeptidase from p. horikoshii in2 complex with amastatin 5 c2pe3A_ 100.0 29 PDB header:hydrolase Chain: A: PDB Molecule:354aa long hypothetical operon protein frv; PDBTitle: crystal structure of frv operon protein frvx (ph1821)from pyrococcus2 horikoshii ot3 6 c3isxA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of endoglucanase (tm1050) from thermotoga2 maritima at 1.40 a resolution 7 c3gb0A_ 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: crystal structure of aminopeptidase pept (np_980509.1) from bacillus2 cereus atcc 10987 at 2.04 a resolution 8 c3rzaA_ 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:tripeptidase; PDBTitle: crystal structure of a tripeptidase (sav1512) from staphylococcus2 aureus subsp. aureus mu50 at 2.10 a resolution 9 c2cf4A_ 100.0 28 PDB header:hydrolase Chain: A: PDB Molecule:protein ph0519; PDBTitle: pyrococcus horikoshii tet1 peptidase can assemble into a2 tetrahedron or a large octahedral shell 10 c3pfoB_ 100.0 11 PDB header:hydrolase Chain: B: PDB Molecule:putative acetylornithine deacetylase; PDBTitle: crystal structure of a putative acetylornithine deacetylase (rpa2325)2 from rhodopseudomonas palustris cga009 at 1.90 a resolution 11 c1cg2D_ 100.0 15 PDB header:metallocarboxypeptidase Chain: D: PDB Molecule:carboxypeptidase g2; PDBTitle: carboxypeptidase g2 12 c1vgyB_ 100.0 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of succinyl diaminopimelate desuccinylase 13 c1vhoA_ 100.0 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of a putative peptidase/endoglucanase 14 c1vixA_ 100.0 11 PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: crystal structure of a putative peptidase t 15 c3tx8A_ 100.0 12 PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of a succinyl-diaminopimelate desuccinylase (arge)2 from corynebacterium glutamicum atcc 13032 at 2.97 a resolution 16 c3ifeA_ 100.0 11 PDB header:hydrolase Chain: A: PDB Molecule:peptidase t; PDBTitle: 1.55 angstrom resolution crystal structure of peptidase t (pept-1)2 from bacillus anthracis str. 'ames ancestor'. 17 c2qyvB_ 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:xaa-his dipeptidase; PDBTitle: crystal structure of putative xaa-his dipeptidase (yp_718209.1) from2 haemophilus somnus 129pt at 2.11 a resolution 18 c2pokB_ 100.0 15 PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m20/m25/m40 family; PDBTitle: crystal structure of a m20 family metallo peptidase from streptococcus2 pneumoniae 19 c3ic1A_ 100.0 9 PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase2 from haemophilus influenzae 20 c2rb7A_ 100.0 12 PDB header:hydrolase Chain: A: PDB Molecule:peptidase, m20/m25/m40 family; PDBTitle: crystal structure of co-catalytic metallopeptidase (yp_387682.1) from2 desulfovibrio desulfuricans g20 at 1.60 a resolution 21 c3mruB_ not modelled 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:aminoacyl-histidine dipeptidase; PDBTitle: crystal structure of aminoacylhistidine dipeptidase from vibrio2 alginolyticus 22 c2imoA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:allantoate amidohydrolase; PDBTitle: crystal structure of allantoate amidohydrolase from escherichia coli2 at ph 4.6 23 c3n5fB_ not modelled 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:n-carbamoyl-l-amino acid hydrolase; PDBTitle: crystal structure of l-n-carbamoylase from geobacillus2 stearothermophilus cect43 24 c2fvgA_ not modelled 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase; PDBTitle: crystal structure of endoglucanase (tm1049) from thermotoga maritima2 at 2.01 a resolution 25 c1ysjB_ not modelled 100.0 10 PDB header:hydrolase Chain: B: PDB Molecule:protein yxep; PDBTitle: crystal structure of bacillus subtilis yxep protein (apc1829), a2 dinuclear metal binding peptidase from m20 family 26 c3dljB_ not modelled 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:beta-ala-his dipeptidase; PDBTitle: crystal structure of human carnosine dipeptidase 1 27 c2v8gD_ not modelled 100.0 13 PDB header:hydrolase Chain: D: PDB Molecule:beta-alanine synthase; PDBTitle: crystal structure of beta-alanine synthase from2 saccharomyces kluyveri in complex with the product beta-3 alanine 28 c2greC_ not modelled 100.0 21 PDB header:hydrolase Chain: C: PDB Molecule:deblocking aminopeptidase; PDBTitle: crystal structure of deblocking aminopeptidase from bacillus cereus 29 c3ramC_ not modelled 100.0 13 PDB header:hydrolase Chain: C: PDB Molecule:hmra protein; PDBTitle: crystal structure of hmra 30 c2zogA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:cytosolic non-specific dipeptidase; PDBTitle: crystal structure of mouse carnosinase cn2 complexed with zn and2 bestatin 31 c3pfeA_ not modelled 100.0 10 PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of a m20a metallo peptidase (dape, lpg0809) from2 legionella pneumophila subsp. pneumophila str. philadelphia 1 at 1.503 a resolution 32 c3ct9B_ not modelled 100.0 11 PDB header:hydrolase Chain: B: PDB Molecule:acetylornithine deacetylase; PDBTitle: crystal structure of a putative zinc peptidase (np_812461.1) from2 bacteroides thetaiotaomicron vpi-5482 at 2.31 a resolution 33 c2f7vA_ not modelled 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:aectylcitrulline deacetylase; PDBTitle: structure of acetylcitrulline deacetylase complexed with2 one co 34 c2q43A_ not modelled 100.0 11 PDB header:hydrolase Chain: A: PDB Molecule:iaa-amino acid hydrolase ilr1-like 2; PDBTitle: ensemble refinement of the protein crystal structure of iaa-aminoacid2 hydrolase from arabidopsis thaliana gene at5g56660 35 c3cpxC_ not modelled 100.0 18 PDB header:hydrolase Chain: C: PDB Molecule:aminopeptidase, m42 family; PDBTitle: crystal structure of putative m42 glutamyl aminopeptidase2 (yp_676701.1) from cytophaga hutchinsonii atcc 33406 at 2.39 a3 resolution 36 c1lfwA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:pepv; PDBTitle: crystal structure of pepv 37 d1vixa1 not modelled 100.0 15 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 38 d1xfoa2 not modelled 100.0 32 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 39 d1yloa2 not modelled 100.0 34 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 40 d1fnoa4 not modelled 100.0 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 41 d1vhea2 not modelled 100.0 26 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 42 d1vhoa2 not modelled 100.0 30 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 43 d1z2la1 not modelled 100.0 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 44 c3khzA_ not modelled 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:putative dipeptidase sacol1801; PDBTitle: crystal structure of r350a mutant of staphylococcus aureus2 metallopeptidase (sapep/dape) in the apo-form 45 d2fvga2 not modelled 100.0 30 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 46 c3l6sA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:aspartyl aminopeptidase; PDBTitle: crystal structure of human aspartyl aminopeptidase (dnpep),2 in complex with aspartic acid hydroxamate 47 c3io1B_ not modelled 99.9 10 PDB header:hydrolase Chain: B: PDB Molecule:aminobenzoyl-glutamate utilization protein; PDBTitle: crystal structure of aminobenzoyl-glutamate utilization2 protein from klebsiella pneumoniae 48 c3t6mA_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase; PDBTitle: crystal structure of the catalytic domain of dape protein from2 v.cholerea in the zn bound form 49 d1lfwa1 not modelled 99.9 19 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 50 c2glfB_ not modelled 99.9 16 PDB header:hydrolase Chain: B: PDB Molecule:probable m18-family aminopeptidase 1; PDBTitle: crystal structure of aminipeptidase (m18 family) from thermotoga2 maritima 51 d2grea2 not modelled 99.9 19 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 52 d1cg2a1 not modelled 99.9 21 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 53 c2ijzF_ not modelled 99.9 18 PDB header:hydrolase Chain: F: PDB Molecule:probable m18-family aminopeptidase 2; PDBTitle: crystal structure of aminopeptidase 54 d1r3na1 not modelled 99.9 18 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 55 c1y7eA_ not modelled 99.8 15 PDB header:hydrolase Chain: A: PDB Molecule:probable m18-family aminopeptidase 1; PDBTitle: the crystal structure of aminopeptidase i from borrelia burgdorferi2 b31 56 d1y0ya2 not modelled 99.8 32 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 57 d1xmba1 not modelled 99.8 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 58 c1q7lA_ not modelled 99.8 10 PDB header:hydrolase Chain: A: PDB Molecule:aminoacylase-1; PDBTitle: zn-binding domain of the t347g mutant of human aminoacylase-2 i 59 d1ysja1 not modelled 99.8 14 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 60 c2gljR_ not modelled 99.8 15 PDB header:hydrolase Chain: R: PDB Molecule: PDBTitle: crystal structure of aminopeptidase i from clostridium2 acetobutylicum 61 d1vgya1 not modelled 99.7 10 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 62 d1y7ea2 not modelled 99.6 20 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 63 d1tkja1 not modelled 99.5 20 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 64 d1rtqa_ not modelled 99.4 16 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Bacterial dinuclear zinc exopeptidases 65 c3tc8A_ not modelled 99.4 19 PDB header:hydrolase Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: crystal structure of a hypothetical zn-dependent exopeptidase2 (bdi_3547) from parabacteroides distasonis atcc 8503 at 1.06 a3 resolution 66 c1q7lB_ not modelled 99.2 17 PDB header:hydrolase Chain: B: PDB Molecule:aminoacylase-1; PDBTitle: zn-binding domain of the t347g mutant of human aminoacylase-2 i 67 c3guxA_ not modelled 99.1 17 PDB header:hydrolase Chain: A: PDB Molecule:putative zn-dependent exopeptidase; PDBTitle: crystal structure of a putative zn-dependent exopeptidase (bvu_1317)2 from bacteroides vulgatus atcc 8482 at 1.80 a resolution 68 c3pb6X_ not modelled 99.0 23 PDB header:transferase Chain: X: PDB Molecule:glutaminyl-peptide cyclotransferase-like protein; PDBTitle: crystal structure of the catalytic domain of human golgi-resident2 glutaminyl cyclase at ph 6.5 69 d2afwa1 not modelled 98.9 16 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Glutaminyl-peptide cyclotransferase-like 70 c2ek8A_ not modelled 98.8 16 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase; PDBTitle: aminopeptidase from aneurinibacillus sp. strain am-1 71 c3iibA_ not modelled 98.7 21 PDB header:hydrolase Chain: A: PDB Molecule:peptidase m28; PDBTitle: crystal structure of peptidase m28 precursor (yp_926796.1) from2 shewanella amazonensis sb2b at 1.70 a resolution 72 d3bi1a3 not modelled 98.5 19 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:FolH catalytic domain-like 73 c2ootA_ not modelled 98.1 21 PDB header:hydrolase Chain: A: PDB Molecule:glutamate carboxypeptidase 2; PDBTitle: a high resolution structure of ligand-free human glutamate2 carboxypeptidase ii 74 d1cg2a2 not modelled 97.9 7 Fold:Ferredoxin-like Superfamily:Bacterial exopeptidase dimerisation domain Family:Bacterial exopeptidase dimerisation domain 75 d1vgya2 not modelled 97.9 8 Fold:Ferredoxin-like Superfamily:Bacterial exopeptidase dimerisation domain Family:Bacterial exopeptidase dimerisation domain 76 c1cx8F_ not modelled 97.8 20 PDB header:metal transport Chain: F: PDB Molecule:transferrin receptor protein; PDBTitle: crytal structure of the ectodomain of human transferrin receptor 77 d1z2la2 not modelled 97.8 13 Fold:Ferredoxin-like Superfamily:Bacterial exopeptidase dimerisation domain Family:Bacterial exopeptidase dimerisation domain 78 d1de4c3 not modelled 97.8 14 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:FolH catalytic domain-like 79 d1r3na2 not modelled 97.5 7 Fold:Ferredoxin-like Superfamily:Bacterial exopeptidase dimerisation domain Family:Bacterial exopeptidase dimerisation domain 80 d1vhea1 not modelled 96.1 34 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Aminopeptidase/glucanase lid domain Family:Aminopeptidase/glucanase lid domain 81 d1lfwa2 not modelled 95.0 10 Fold:Ferredoxin-like Superfamily:Bacterial exopeptidase dimerisation domain Family:Bacterial exopeptidase dimerisation domain 82 d1ysja2 not modelled 94.9 4 Fold:Ferredoxin-like Superfamily:Bacterial exopeptidase dimerisation domain Family:Bacterial exopeptidase dimerisation domain 83 c3k9tA_ not modelled 93.8 11 PDB header:hydrolase Chain: A: PDB Molecule:putative peptidase; PDBTitle: crystal structure of putative peptidase (np_348812.1) from clostridium2 acetobutylicum at 2.37 a resolution 84 d2grea1 not modelled 91.5 26 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Aminopeptidase/glucanase lid domain Family:Aminopeptidase/glucanase lid domain 85 d1y0ya1 not modelled 81.4 35 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Aminopeptidase/glucanase lid domain Family:Aminopeptidase/glucanase lid domain 86 d1xmba2 not modelled 79.4 12 Fold:Ferredoxin-like Superfamily:Bacterial exopeptidase dimerisation domain Family:Bacterial exopeptidase dimerisation domain 87 d1yloa1 not modelled 74.1 30 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Aminopeptidase/glucanase lid domain Family:Aminopeptidase/glucanase lid domain 88 d1vhoa1 not modelled 66.2 31 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Aminopeptidase/glucanase lid domain Family:Aminopeptidase/glucanase lid domain 89 d2fvga1 not modelled 64.5 32 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Aminopeptidase/glucanase lid domain Family:Aminopeptidase/glucanase lid domain 90 c3hlyA_ not modelled 49.7 8 PDB header:flavoprotein Chain: A: PDB Molecule:flavodoxin-like domain; PDBTitle: crystal structure of the flavodoxin-like domain from2 synechococcus sp q5mzp6_synp6 protein. northeast structural3 genomics consortium target snr135d. 91 c3fniA_ not modelled 47.5 12 PDB header:oxidoreductase Chain: A: PDB Molecule:putative diflavin flavoprotein a 3; PDBTitle: crystal structure of a diflavin flavoprotein a3 (all3895) from nostoc2 sp., northeast structural genomics consortium target nsr431a 92 c3qnmA_ not modelled 43.4 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:haloacid dehalogenase-like hydrolase; PDBTitle: haloalkane dehalogenase family member from bacteroides2 thetaiotaomicron of unknown function 93 d1vmea1 not modelled 41.6 8 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 94 d1e5da1 not modelled 39.9 19 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 95 c3ij3A_ not modelled 39.3 12 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: 1.8 angstrom resolution crystal structure of cytosol aminopeptidase2 from coxiella burnetii 96 d1ycga1 not modelled 38.6 12 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 97 c3na6A_ not modelled 38.5 10 PDB header:hydrolase Chain: A: PDB Molecule:succinylglutamate desuccinylase/aspartoacylase; PDBTitle: crystal structure of a succinylglutamate desuccinylase (tm1040_2694)2 from silicibacter sp. tm1040 at 2.00 a resolution 98 c1sz1A_ not modelled 38.0 15 PDB header:transferase/rna Chain: A: PDB Molecule:trna nucleotidyltransferase; PDBTitle: mechanism of cca-adding enzymes specificity revealed by crystal2 structures of ternary complexes 99 d2fz5a1 not modelled 37.0 17 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 100 c2k9mA_ not modelled 36.3 21 PDB header:transcription Chain: A: PDB Molecule:rna polymerase sigma factor rpon; PDBTitle: structure of the core binding domain of sigma54 101 c3kzwD_ not modelled 35.8 10 PDB header:hydrolase Chain: D: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from staphylococcus aureus2 col 102 c2k9lA_ not modelled 35.5 21 PDB header:transcription Chain: A: PDB Molecule:rna polymerase sigma factor rpon; PDBTitle: structure of the core binding domain of sigma54 103 d1r89a2 not modelled 35.2 24 Fold:Nucleotidyltransferase Superfamily:Nucleotidyltransferase Family:Archaeal tRNA CCA-adding enzyme catalytic domain 104 c2hnbA_ not modelled 34.6 9 PDB header:electron transport Chain: A: PDB Molecule:protein mioc; PDBTitle: solution structure of a bacterial holo-flavodoxin 105 c3f6sI_ not modelled 34.0 15 PDB header:electron transport Chain: I: PDB Molecule:flavodoxin; PDBTitle: desulfovibrio desulfuricans (atcc 29577) oxidized flavodoxin2 alternate conformers 106 d1lama1 not modelled 31.4 14 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Leucine aminopeptidase, C-terminal domain 107 c2ho4A_ not modelled 30.8 7 PDB header:hydrolase Chain: A: PDB Molecule:haloacid dehalogenase-like hydrolase domain PDBTitle: crystal structure of protein from mouse mm.236127 108 c1bvyF_ not modelled 29.5 7 PDB header:oxidoreductase Chain: F: PDB Molecule:protein (cytochrome p450 bm-3); PDBTitle: complex of the heme and fmn-binding domains of the2 cytochrome p450(bm-3) 109 d1bvyf_ not modelled 29.5 7 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 110 d1f4pa_ not modelled 29.2 19 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 111 d1ykga1 not modelled 28.4 9 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 112 d5nula_ not modelled 28.3 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 113 c3fd0B_ not modelled 28.0 11 PDB header:lyase Chain: B: PDB Molecule:putative cystathionine beta-lyase involved in aluminum PDBTitle: crystal structure of putative cystathionine beta-lyase involved in2 aluminum resistance (np_470671.1) from listeria innocua at 2.12 a3 resolution 114 d1b1ca_ not modelled 27.9 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 115 c3pdwA_ not modelled 26.5 15 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized hydrolase yutf; PDBTitle: crystal structure of putative p-nitrophenyl phosphatase from bacillus2 subtilis 116 d2o2xa1 not modelled 26.1 13 Fold:HAD-like Superfamily:HAD-like Family:Histidinol phosphatase-like 117 c1lanA_ not modelled 25.9 15 PDB header:hydrolase (alpha-aminoacylpeptide) Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: leucine aminopeptidase complex with l-leucinal 118 d1x42a1 not modelled 25.2 14 Fold:HAD-like Superfamily:HAD-like Family:HAD-related 119 c3peiA_ not modelled 25.2 8 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis 120 c2pkeA_ not modelled 23.8 19 PDB header:hydrolase Chain: A: PDB Molecule:haloacid delahogenase-like family hydrolase; PDBTitle: crystal structure of haloacid delahogenase-like family hydrolase2 (np_639141.1) from xanthomonas campestris at 1.81 a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0