BLASTP 2.2.22 [Sep-27-2009]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= batch____
         (152 letters)

Database: uniref50.fasta 
           3,077,464 sequences; 1,040,396,356 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_B7UN42 Methylglyoxal synthase n=174 Tax=Bacteria RepID=...   234   6e-61
UniRef50_B5XY41 Methylglyoxal synthase n=65 Tax=Gammaproteobacte...   228   5e-59
UniRef50_Q4QJW2 Methylglyoxal synthase n=45 Tax=cellular organis...   217   1e-55
UniRef50_Q72NU6 Methylglyoxal synthase n=20 Tax=Bacteria RepID=M...   215   4e-55
UniRef50_B8I1E7 Methylglyoxal synthase n=13 Tax=Firmicutes RepID...   212   3e-54
UniRef50_A4BFH8 Methylglyoxal synthase n=1 Tax=Reinekea blandens...   211   6e-54
UniRef50_Q2SK75 Methylglyoxal synthase n=2 Tax=Gammaproteobacter...   208   3e-53
UniRef50_A9KFK7 Methylglyoxal synthase n=6 Tax=Coxiella burnetii...   208   3e-53
UniRef50_C6BZQ4 Methylglyoxal synthase n=7 Tax=Bacteria RepID=MG...   206   2e-52
UniRef50_Q1QX97 Methylglyoxal synthase n=4 Tax=Bacteria RepID=Q1...   203   1e-51
UniRef50_B9MRV5 Methylglyoxal synthase n=158 Tax=cellular organi...   201   5e-51
UniRef50_A0LVE0 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A0...   199   2e-50
UniRef50_UPI0001745D5F methylglyoxal synthase n=1 Tax=Verrucomic...   195   4e-49
UniRef50_A6L618 Methylglyoxal synthase n=34 Tax=Bacteroidales Re...   194   9e-49
UniRef50_A4IQ66 Methylglyoxal synthase n=37 Tax=Bacteria RepID=M...   192   2e-48
UniRef50_B0KAD1 Methylglyoxal synthase n=27 Tax=cellular organis...   191   6e-48
UniRef50_C1TMX7 Methylglyoxal synthase n=1 Tax=Dethiosulfovibrio...   190   8e-48
UniRef50_B1YKL9 Methylglyoxal synthase n=78 Tax=Bacteria RepID=M...   188   5e-47
UniRef50_D0MG34 Methylglyoxal synthase n=1 Tax=Rhodothermus mari...   185   3e-46
UniRef50_Q3AGN5 Cyclic nucleotide-binding domain (CNMP-BD) prote...   185   5e-46
UniRef50_UPI0000E11027 methylglyoxal synthase n=1 Tax=Rhodobacte...   185   5e-46
UniRef50_C2HDU2 Methylglyoxal synthase n=12 Tax=Enterococcus fae...   185   5e-46
UniRef50_D2BG68 Methylglyoxal synthase n=5 Tax=Dehalococcoides R...   181   4e-45
UniRef50_C9KKW1 Methylglyoxal synthase n=1 Tax=Mitsuokella multa...   181   6e-45
UniRef50_Q2RSM7 Methylglyoxal synthase n=1 Tax=Rhodospirillum ru...   180   1e-44
UniRef50_Q10YJ6 Cyclic nucleotide-binding protein n=2 Tax=Bacter...   180   2e-44
UniRef50_Q8UIV6 Methylglyoxal synthase n=8 Tax=Alphaproteobacter...   180   2e-44
UniRef50_P58761 Methylglyoxal synthase n=6 Tax=Bacteria RepID=MG...   175   3e-43
UniRef50_Q72HP3 Methylglyoxal synthase n=3 Tax=Bacteria RepID=MG...   175   4e-43
UniRef50_C4ZA41 Methylglyoxal synthase n=10 Tax=Firmicutes RepID...   175   5e-43
UniRef50_Q55452 Uncharacterized protein sll0036 n=7 Tax=Bacteria...   173   2e-42
UniRef50_C3MBY3 Methylglyoxal synthase n=5 Tax=Alphaproteobacter...   173   2e-42
UniRef50_A3MI51 Methylglyoxal synthase n=96 Tax=Bacteria RepID=M...   170   2e-41
UniRef50_C1MXR9 Predicted protein n=1 Tax=Micromonas pusilla CCM...   168   4e-41
UniRef50_B3PXK7 Methylglyoxal synthase n=23 Tax=Bacteria RepID=M...   166   3e-40
UniRef50_A5FPH5 Methylglyoxal synthase n=5 Tax=Dehalococcoides R...   165   3e-40
UniRef50_A7HN41 Methylglyoxal synthase n=1 Tax=Fervidobacterium ...   164   6e-40
UniRef50_A4J7I4 Methylglyoxal synthase n=1 Tax=Desulfotomaculum ...   163   2e-39
UniRef50_C9L646 Methylglyoxal synthase n=12 Tax=Bacteria RepID=C...   162   3e-39
UniRef50_A5FB35 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A5...   157   1e-37
UniRef50_B0C5A3 Putative uncharacterized protein n=1 Tax=Acaryoc...   152   3e-36
UniRef50_Q0FI67 Methylglyoxal synthase n=3 Tax=Rhodobacteraceae ...   147   9e-35
UniRef50_B4SH52 Methylglyoxal synthase-like protein n=2 Tax=cell...   143   2e-33
UniRef50_B7S3K0 Predicted protein n=1 Tax=Phaeodactylum tricornu...   143   2e-33
UniRef50_B2IW98 Forkhead-associated protein n=1 Tax=Nostoc punct...   140   2e-32
UniRef50_B5VUE7 Diacylglycerol kinase catalytic region n=2 Tax=A...   133   2e-30
UniRef50_A0YM60 Putative uncharacterized protein n=1 Tax=Lyngbya...   129   2e-29
UniRef50_D0J1U7 Methylglyoxal synthase n=3 Tax=Comamonadaceae Re...   128   6e-29
UniRef50_A3YU56 Methylglyoxal synthase n=2 Tax=Synechococcus Rep...   116   2e-25
UniRef50_A5FYW1 Methylglyoxal synthase-like protein n=4 Tax=Prot...   111   5e-24
UniRef50_A6SWW2 Uncharacterized conserved protein n=12 Tax=cellu...   110   2e-23
UniRef50_Q05TV7 Methylglyoxal synthase n=1 Tax=Synechococcus sp....   106   3e-22
UniRef50_B1YIR9 Carbamoyl-phosphate synthase large chain n=54 Ta...    87   2e-16
UniRef50_B8BWS2 Predicted protein n=1 Tax=Thalassiosira pseudona...    71   8e-12
UniRef50_UPI0001B41F6C carbamoyl phosphate synthase large subuni...    58   1e-07
UniRef50_C9KKE3 Carbamoyl-phosphate synthase, large subunit n=1 ...    57   2e-07
UniRef50_B9KXM5 Carbamoyl-phosphate synthase large chain n=794 T...    52   6e-06
UniRef50_C9LZI0 Carbamoyl-phosphate synthase large subunit chain...    51   1e-05
UniRef50_A5D508 Carbamoyl-phosphate synthase large chain n=178 T...    51   1e-05
UniRef50_B2A170 Carbamoyl-phosphate synthase large chain n=3 Tax...    50   3e-05
UniRef50_O67233 Carbamoyl-phosphate synthase large chain, C-term...    50   3e-05
UniRef50_A6CPS0 Carbamoyl-phosphate synthase large subunit n=2 T...    48   8e-05
UniRef50_A2BWE6 Carbamoyl-phosphate synthase, large subunit n=56...    45   9e-04
UniRef50_C6Q1M4 MGS domain protein n=1 Tax=Clostridium carboxidi...    45   0.001
UniRef50_Q9HK17 Carbamoyl-phosphate synthase large chain n=4 Tax...    44   0.002
UniRef50_D1CBW2 Carbamoyl-phosphate synthase, large subunit n=1 ...    44   0.002
UniRef50_D1Y1S0 Carbamoyl-phosphate synthase, large subunit n=2 ...    42   0.007
UniRef50_Q9CKV0 Carbamoyl-phosphate synthase large chain n=6 Tax...    42   0.007
UniRef50_O93937 Aspartate carbamoyltransferase n=344 Tax=cellula...    41   0.008
UniRef50_P07259 Aspartate carbamoyltransferase n=65 Tax=cellular...    41   0.011
UniRef50_Q58776 Carbamoyl-phosphate synthase large chain, C-term...    41   0.014
UniRef50_A9QP20 Carbamoyl phosphate synthetase ammonia large cha...    40   0.019
UniRef50_B0U8L9 Carbamoyl-phosphate synthase, large subunit n=3 ...    39   0.034
UniRef50_Q03WW7 Carbamoyl-phosphate synthase large chain n=115 T...    39   0.037
UniRef50_C3XFR9 Carbamoyl-phosphate synthase subunit large n=1 T...    39   0.047

>UniRef50_B7UN42 Methylglyoxal synthase n=174 Tax=Bacteria RepID=MGSA_ECO27
          Length = 152

 Score =  234 bits (598), Expect = 6e-61,   Method: Composition-based stats.
 Identities = 151/152 (99%), Positives = 152/152 (100%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           MELTTRTLP+RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV
Sbjct: 1   MELTTRTLPSRKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
           NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV
Sbjct: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
           ATADFIIQSPHFNDAVDILIPDYQRYLADRLK
Sbjct: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152


>UniRef50_B5XY41 Methylglyoxal synthase n=65 Tax=Gammaproteobacteria
           RepID=MGSA_KLEP3
          Length = 152

 Score =  228 bits (581), Expect = 5e-59,   Method: Composition-based stats.
 Identities = 136/152 (89%), Positives = 142/152 (93%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           MELTTRTL A+KHIALVAHDHCK MLM WV RHQ LL QHVLYATGTTGNL+SRATG+ V
Sbjct: 1   MELTTRTLSAQKHIALVAHDHCKDMLMKWVARHQALLAQHVLYATGTTGNLVSRATGLEV 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
           NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV
Sbjct: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
           +TADFIIQSPHFN  +DILIPDY RYLA+RLK
Sbjct: 121 STADFIIQSPHFNQPLDILIPDYPRYLAERLK 152


>UniRef50_Q4QJW2 Methylglyoxal synthase n=45 Tax=cellular organisms RepID=MGSA_HAEI8
          Length = 152

 Score =  217 bits (552), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 91/151 (60%), Positives = 123/151 (81%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M+ TTRTL   K IALVAHD CK+ L++W ++H+  L+ H+LYATGTTG+++ R TG+++
Sbjct: 1   MQTTTRTLTQHKRIALVAHDSCKKNLLNWTQKHKEALKPHILYATGTTGHILERETGLSI 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
            ++LSGPMGGDQQ+G LI+E KID++IFFWDP+NA PHDPDVKAL+R+ATVWNIPVA N 
Sbjct: 61  QSLLSGPMGGDQQLGGLIAEKKIDMMIFFWDPMNAAPHDPDVKALMRIATVWNIPVAINQ 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRL 151
           ++ADF++ S  F   V+I +PDY+ YL +RL
Sbjct: 121 SSADFLLTSVLFEQDVEIDVPDYEGYLKERL 151


>UniRef50_Q72NU6 Methylglyoxal synthase n=20 Tax=Bacteria RepID=MGSA_LEPIC
          Length = 148

 Score =  215 bits (548), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 74/139 (53%), Positives = 102/139 (73%)

Query: 7   TLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSG 66
           ++PA K I L+AHD+ K+ L++WV+ H+ +L +H LY TGTTG LIS  T + V   LSG
Sbjct: 5   SVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYRFLSG 64

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GA I+EG +D++IFFWDPL A PHDPDVKALLR+A ++N+P+A N +TAD++
Sbjct: 65  PLGGDQQIGAKIAEGDLDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRSTADYM 124

Query: 127 IQSPHFNDAVDILIPDYQR 145
           I SP F      ++  Y  
Sbjct: 125 ISSPQFTKTYKKILLSYNT 143


>UniRef50_B8I1E7 Methylglyoxal synthase n=13 Tax=Firmicutes RepID=B8I1E7_CLOCE
          Length = 153

 Score =  212 bits (540), Expect = 3e-54,   Method: Composition-based stats.
 Identities = 68/141 (48%), Positives = 98/141 (69%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
           ++   L  +KHIAL+AHD+ K+ L++WV+    +L +H L  TGTT  +I+  TG+ V  
Sbjct: 1   MSGNKLGRQKHIALIAHDNRKEDLINWVKSKSDILCRHFLCGTGTTAKMITENTGLPVKK 60

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
             SGP+GGDQQ+GA I+ G++D +IFFWD L + PHDPDVKALLR+A +++IPVA N +T
Sbjct: 61  FKSGPLGGDQQIGACIANGEVDFMIFFWDTLTSQPHDPDVKALLRIAVLYDIPVAMNRST 120

Query: 123 ADFIIQSPHFNDAVDILIPDY 143
           ADF++ S    D  +  + DY
Sbjct: 121 ADFLLTSSLMEDDYERNVVDY 141


>UniRef50_A4BFH8 Methylglyoxal synthase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BFH8_9GAMM
          Length = 147

 Score =  211 bits (537), Expect = 6e-54,   Method: Composition-based stats.
 Identities = 72/142 (50%), Positives = 98/142 (69%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
            +++IALVAHD+ K+ L+ W      L+ +  ++ATGTTG LI  A    VN +LSGP+G
Sbjct: 2   KQRNIALVAHDNKKKELVDWAVAKAELMAEIGIFATGTTGRLIEDAMKRPVNRLLSGPLG 61

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GDQQ+GA I+EG+ID+LIFFWDPL   PHDPD+KALLR+A ++NIPVA N A+AD++I S
Sbjct: 62  GDQQIGAKIAEGEIDLLIFFWDPLEPQPHDPDIKALLRIAALYNIPVACNKASADYMIHS 121

Query: 130 PHFNDAVDILIPDYQRYLADRL 151
           P  +       PD+  Y   + 
Sbjct: 122 PLLHGDYVPDEPDFSDYTLRKT 143


>UniRef50_Q2SK75 Methylglyoxal synthase n=2 Tax=Gammaproteobacteria RepID=MGSA_HAHCH
          Length = 153

 Score =  208 bits (531), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 77/136 (56%), Positives = 101/136 (74%), Gaps = 1/136 (0%)

Query: 14  IALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQ 73
           +AL+AHD+ K  L++WVE++   L +  +YATGTTG LI+  TG++V    SGP+GGDQQ
Sbjct: 14  VALIAHDNKKADLIAWVEKNSVKLNKCTVYATGTTGKLIAEKTGVDVKRCHSGPLGGDQQ 73

Query: 74  VGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFN 133
           +GALISEGK+D+LIFFWDPL  +PHDPD+KALLRLAT+WN+P A N ATADF++ S  F 
Sbjct: 74  IGALISEGKVDLLIFFWDPLEPMPHDPDIKALLRLATLWNVPSACNSATADFLVNSNLFE 133

Query: 134 DAVDILIPDYQRYLAD 149
                  PD+  YL+ 
Sbjct: 134 -EFLPQRPDFDSYLSR 148


>UniRef50_A9KFK7 Methylglyoxal synthase n=6 Tax=Coxiella burnetii RepID=MGSA_COXBN
          Length = 143

 Score =  208 bits (531), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 75/138 (54%), Positives = 97/138 (70%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           K IALVAHD  K+ L+ W+++HQ LL+ H LYATG+TG  I +   + V  M SGP+GGD
Sbjct: 4   KKIALVAHDRMKKELIEWIKKHQNLLKHHELYATGSTGQAIEKTLNVTVTKMESGPLGGD 63

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
            Q+GA I   +ID+LIFFWDPL A PHDPDV+ALLR+A VWN+PVA N +TAD+++ SP 
Sbjct: 64  LQLGAKIVNKEIDILIFFWDPLEAQPHDPDVRALLRIAVVWNLPVACNASTADYLLTSPL 123

Query: 132 FNDAVDILIPDYQRYLAD 149
           F+       PDY+ Y   
Sbjct: 124 FDSDYHPETPDYEAYRNR 141


>UniRef50_C6BZQ4 Methylglyoxal synthase n=7 Tax=Bacteria RepID=MGSA_DESAD
          Length = 157

 Score =  206 bits (524), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 77/157 (49%), Positives = 102/157 (64%), Gaps = 13/157 (8%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT----------G 57
           +   K+IA+VAHD+CK+ L+ +V+ +  +L +H L ATGTTG L+ +            G
Sbjct: 1   MSKVKNIAVVAHDNCKKELLDFVDCNHNILSRHNLVATGTTGGLVEKMIMERVEQKADEG 60

Query: 58  M---NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNI 114
                VN M SGP+GGDQQ+GA+ISEGKIDVLIFFWDP+   PHD DVKALLRLA ++NI
Sbjct: 61  YEFKPVNRMKSGPLGGDQQLGAMISEGKIDVLIFFWDPMQPQPHDVDVKALLRLAVLYNI 120

Query: 115 PVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRL 151
           P A+N +TA+F+I SP F         D+  Y   +L
Sbjct: 121 PTASNRSTAEFLISSPFFEGEFQRKETDFSSYTQRKL 157


>UniRef50_Q1QX97 Methylglyoxal synthase n=4 Tax=Bacteria RepID=Q1QX97_CHRSD
          Length = 159

 Score =  203 bits (517), Expect = 1e-51,   Method: Composition-based stats.
 Identities = 81/149 (54%), Positives = 106/149 (71%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              TRTLPARK IAL+AHD  K  L++W ER +  L +H L  TGTT   ++   G+ V+
Sbjct: 8   RQATRTLPARKRIALIAHDGKKAELLAWAERWRDTLARHDLVGTGTTAQRVAETLGLEVH 67

Query: 62  AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            ++SGP+GGDQQ+GA I+E ++D+L+FFWDP   +PHDPDVKALLRLA +WN+PVATN A
Sbjct: 68  GLMSGPLGGDQQIGARITESRLDMLVFFWDPFAPMPHDPDVKALLRLAALWNLPVATNAA 127

Query: 122 TADFIIQSPHFNDAVDILIPDYQRYLADR 150
           +ADFII SP     V + +PD   +LA R
Sbjct: 128 SADFIITSPLVAQEVTVNVPDANDWLATR 156


>UniRef50_B9MRV5 Methylglyoxal synthase n=158 Tax=cellular organisms
           RepID=MGSA_ANATD
          Length = 141

 Score =  201 bits (512), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 68/141 (48%), Positives = 100/141 (70%), Gaps = 2/141 (1%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K++++ +   ++ +L +H LYATGTTG LI  ATG+ V+  L GP+GGD
Sbjct: 1   MNIALIAHDKKKELMVQFAIAYKFILSKHTLYATGTTGRLIQEATGLEVHRFLPGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+G+LI+  +ID++IF  DPL A PH+PDV ALLRL  V NIP+ATN+ATA+ +I++  
Sbjct: 61  QQIGSLIAYNQIDMVIFLRDPLTAQPHEPDVNALLRLCDVHNIPLATNIATAELLIKALD 120

Query: 132 FNDA--VDILIPDYQRYLADR 150
             D    +I+ P  Q+  +D+
Sbjct: 121 RGDLSWREIVNPKLQKNKSDK 141


>UniRef50_A0LVE0 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A0LVE0_ACIC1
          Length = 167

 Score =  199 bits (507), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 73/145 (50%), Positives = 96/145 (66%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M     T   R+HIALVAHD+ K+ L+ W   ++  L QH LYATGTTG L+     + +
Sbjct: 1   MTTQALTGTPRRHIALVAHDNKKRELLEWAAYNRATLAQHELYATGTTGALLREQLDLEI 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +LSGP+GGD Q+GA I+ G +D+L+FFWDPL   PHDPDVKALLR+A +WNI +A N 
Sbjct: 61  RCLLSGPLGGDLQIGAQIAAGSVDLLVFFWDPLEPQPHDPDVKALLRVAVLWNIAIACNR 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQR 145
            TAD +I SP F+    I  P Y++
Sbjct: 121 TTADMVISSPLFSGPYQIHRPTYRQ 145


>UniRef50_UPI0001745D5F methylglyoxal synthase n=1 Tax=Verrucomicrobium spinosum DSM 4136
           RepID=UPI0001745D5F
          Length = 154

 Score =  195 bits (496), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 72/138 (52%), Positives = 95/138 (68%), Gaps = 1/138 (0%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
            I LVAHDHCK  L++W ++H+  L+   L ATGTTG+L+ +  G+ V   LSGP+GGD 
Sbjct: 3   TIGLVAHDHCKDNLLAWAQKHREQLQGWTLCATGTTGSLLEKELGLPVRRFLSGPLGGDL 62

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           Q+G  I+EG++D+LIFFWDPL+A PHDPDVKALLR+A +WN+PVA N A AD ++     
Sbjct: 63  QIGTEIAEGRMDLLIFFWDPLSAQPHDPDVKALLRVAVLWNVPVAMNEAGADLLLIGLAQ 122

Query: 133 NDAVDILIPDYQRYLADR 150
                  IPD+  Y A R
Sbjct: 123 G-TYQRFIPDHTNYRAVR 139


>UniRef50_A6L618 Methylglyoxal synthase n=34 Tax=Bacteroidales RepID=A6L618_BACV8
          Length = 178

 Score =  194 bits (493), Expect = 9e-49,   Method: Composition-based stats.
 Identities = 67/146 (45%), Positives = 84/146 (57%), Gaps = 8/146 (5%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA-------TGMNVNAML 64
           + I LVAHD  K+ ++ WV  +   L  H  Y TGTTG LI +A          ++  + 
Sbjct: 6   RRIGLVAHDAMKKDMIEWVLWNSERLIGHKFYCTGTTGTLIKKALEEKHPEIKWDITILK 65

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
           SGP+GGDQQ+G+ I EG+ID L FF DP+   PHD DVKAL RLA V NI    N +TAD
Sbjct: 66  SGPLGGDQQIGSRIVEGEIDYLFFFTDPMTLQPHDTDVKALTRLAGVENIVFCCNRSTAD 125

Query: 125 FIIQSPHFNDA-VDILIPDYQRYLAD 149
            II SP F D   + + PDY  Y   
Sbjct: 126 HIITSPLFTDPTYERIHPDYTNYTQR 151


>UniRef50_A4IQ66 Methylglyoxal synthase n=37 Tax=Bacteria RepID=MGSA_GEOTN
          Length = 144

 Score =  192 bits (489), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 58/123 (47%), Positives = 85/123 (69%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
             IAL+AHD  K  ++++   + P+L  H LYATGTTG  I  ATG+ V+   SGP GGD
Sbjct: 1   MKIALIAHDEKKAEMVAFATAYAPVLANHELYATGTTGLRIQEATGLAVHRFQSGPYGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           Q++GA+I+  ++D++IFF DPL A PH+PD+ AL+RL  V+ +P+ATN+ TA+ +I+   
Sbjct: 61  QEIGAMIARNEMDLVIFFRDPLTAQPHEPDISALMRLCDVYAVPLATNIGTAELLIRGLE 120

Query: 132 FND 134
             D
Sbjct: 121 RGD 123


>UniRef50_B0KAD1 Methylglyoxal synthase n=27 Tax=cellular organisms RepID=MGSA_THEP3
          Length = 132

 Score =  191 bits (486), Expect = 6e-48,   Method: Composition-based stats.
 Identities = 62/131 (47%), Positives = 93/131 (70%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K++++++   ++ + E+  +YATG TG LI  ATG+NVN +L GP+GGD
Sbjct: 1   MNIALIAHDQKKELMVNFAIAYKHIFEKCNIYATGHTGQLIKEATGLNVNCLLPGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA+I+E KID++IF  DPL A PH+PD+ ALLR+  V +IP+ATN+ATA+ +++   
Sbjct: 61  QQIGAMIAENKIDMVIFLRDPLTAQPHEPDILALLRVCDVHSIPLATNIATAEVLLKGME 120

Query: 132 FNDAVDILIPD 142
                   I D
Sbjct: 121 QGLLEWREIED 131


>UniRef50_C1TMX7 Methylglyoxal synthase n=1 Tax=Dethiosulfovibrio peptidovorans DSM
           11002 RepID=C1TMX7_9BACT
          Length = 157

 Score =  190 bits (484), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 66/143 (46%), Positives = 96/143 (67%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
           + A K IALVAHD  K+ L+ W +RH+  L  H L +TGTTG L+  A G+ ++ + SGP
Sbjct: 1   MEAVKKIALVAHDSRKKDLIRWAKRHREQLAAHRLCSTGTTGALLEAALGLPIDKLKSGP 60

Query: 68  MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
           +GGDQQ+GA I+  ++D ++F WDPLN   HD D+KALLR+AT++NIP+A N+A+ADF+ 
Sbjct: 61  LGGDQQLGARIACERLDAIVFLWDPLNTQAHDSDIKALLRIATLYNIPMACNMASADFLF 120

Query: 128 QSPHFNDAVDILIPDYQRYLADR 150
            SP  +   +    D+  +   R
Sbjct: 121 SSPLISLPYNNEHRDFDAHQQAR 143


>UniRef50_B1YKL9 Methylglyoxal synthase n=78 Tax=Bacteria RepID=MGSA_EXIS2
          Length = 144

 Score =  188 bits (477), Expect = 5e-47,   Method: Composition-based stats.
 Identities = 56/123 (45%), Positives = 84/123 (68%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K  +M +   ++    ++ LYATGTTG  I  AT + V+   SGP+GGD
Sbjct: 1   MNIALIAHDEKKDEMMMFTRAYEAYFAKNTLYATGTTGQRIMEATALTVHRCKSGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           Q++GA+++ G+ID++IF  DPL A PH+PDV AL+RL  V+++P+ATNV TA+ +I    
Sbjct: 61  QEIGAMVARGEIDIVIFLRDPLTAQPHEPDVSALIRLCDVYDLPLATNVGTAEILINGLE 120

Query: 132 FND 134
             +
Sbjct: 121 QGE 123


>UniRef50_D0MG34 Methylglyoxal synthase n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MG34_RHOM4
          Length = 140

 Score =  185 bits (471), Expect = 3e-46,   Method: Composition-based stats.
 Identities = 54/121 (44%), Positives = 76/121 (62%)

Query: 9   PARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM 68
              + IAL+AHD  K  ++++  +H+ LL +  L  TGTTG L+    G+ V   LSGP+
Sbjct: 3   ETIRTIALIAHDGKKADMVAFAMQHRDLLARFELVGTGTTGKLLEEKVGLRVRRFLSGPL 62

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
           GGD Q+ A +  G I  + FF DPL+  PHDPD++ LLR   V N+P+ATN ATA +I+ 
Sbjct: 63  GGDVQIAARVVTGDIHAVFFFVDPLDKHPHDPDIQTLLRACNVHNVPLATNPATAHYILT 122

Query: 129 S 129
           S
Sbjct: 123 S 123


>UniRef50_Q3AGN5 Cyclic nucleotide-binding domain (CNMP-BD) protein n=1
           Tax=Synechococcus sp. CC9605 RepID=Q3AGN5_SYNSC
          Length = 297

 Score =  185 bits (469), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 58/148 (39%), Positives = 89/148 (60%), Gaps = 3/148 (2%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA-MLSG 66
              RK++AL+AH++ K+ LM +   H   LE+  L ATGTTG+++ + TG+ ++  + SG
Sbjct: 145 TDTRKYLALIAHNNMKESLMEFCGMHSRKLEKFPLMATGTTGSMLYKKTGLVLSKKVASG 204

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQ VG LIS   I  +IFF DPL+  PH  D++AL RL  V+ +P ATN  + + I
Sbjct: 205 PLGGDQAVGTLISTRNIIGVIFFRDPLSPHPHHADIEALGRLCDVYQVPFATNPQSGEAI 264

Query: 127 IQSPHFNDAVDILIPDY--QRYLADRLK 152
           +       +    IP++  Q Y+  + K
Sbjct: 265 LDYLLSGKSERESIPNHVLQTYIQGQTK 292


>UniRef50_UPI0000E11027 methylglyoxal synthase n=1 Tax=Rhodobacterales bacterium HTCC2255
           RepID=UPI0000E11027
          Length = 151

 Score =  185 bits (469), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 69/146 (47%), Positives = 94/146 (64%), Gaps = 2/146 (1%)

Query: 5   TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAM 63
           T+T    K IA+VAHD  K   + W + H   L  H ++ATGTTG LI  A   +++ A+
Sbjct: 2   TQTTVVTKRIAIVAHDKMKPQAIEWTKTHASKLNSHQIFATGTTGKLIQAANPNLSIKAL 61

Query: 64  LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
            SGP+GGDQQ+GA+I EG++D+L FF DP+   PHD D+KALLRL+T++N  VA N+ATA
Sbjct: 62  KSGPLGGDQQLGAMICEGQLDILFFFTDPMTPQPHDVDIKALLRLSTMYNCVVACNIATA 121

Query: 124 DFIIQSPHFNDAVDILIPDYQRYLAD 149
           DF+I+SP F         D+  Y   
Sbjct: 122 DFVIESPLFVLP-QTHTSDFSDYSER 146


>UniRef50_C2HDU2 Methylglyoxal synthase n=12 Tax=Enterococcus faecium
           RepID=C2HDU2_ENTFC
          Length = 150

 Score =  185 bits (469), Expect = 5e-46,   Method: Composition-based stats.
 Identities = 61/131 (46%), Positives = 91/131 (69%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
           LT     +   IAL+AHD  K M++     ++ +LE+H L+ATGTTG  I+ ATG+ ++ 
Sbjct: 2   LTISKGVSLMKIALIAHDRKKSMMVKLATAYKTILEKHELFATGTTGQRITEATGLPIHR 61

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
             SGP+GGDQQ+GA+ISE ++D++IF  DPL A PH+PDV AL+RL+ V+ IP+ATN+ T
Sbjct: 62  FKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYEIPLATNIGT 121

Query: 123 ADFIIQSPHFN 133
           A+ +++     
Sbjct: 122 AEVLLRGLEAG 132


>UniRef50_D2BG68 Methylglyoxal synthase n=5 Tax=Dehalococcoides RepID=D2BG68_DEHSV
          Length = 144

 Score =  181 bits (461), Expect = 4e-45,   Method: Composition-based stats.
 Identities = 59/142 (41%), Positives = 91/142 (64%), Gaps = 1/142 (0%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
            R  +ALVAHD+ KQ ++  V++H+  L    L AT TTG LI  +T +NVN + SGP+G
Sbjct: 2   ERITLALVAHDNKKQEMVELVKKHETDLGSLNLVATRTTGKLIQASTSLNVNLLQSGPLG 61

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GDQQ+GA+++ G +  +IF  DPL A PH+PD+ AL+R+  V N+P+ATN++TA+ ++  
Sbjct: 62  GDQQIGAMVASGVVTAIIFLRDPLTAQPHEPDISALMRVCDVHNVPLATNISTAEAVLH- 120

Query: 130 PHFNDAVDILIPDYQRYLADRL 151
             F    ++     +  L + L
Sbjct: 121 LIFEHPEELKEHRLKSQLLNSL 142


>UniRef50_C9KKW1 Methylglyoxal synthase n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KKW1_9FIRM
          Length = 132

 Score =  181 bits (460), Expect = 6e-45,   Method: Composition-based stats.
 Identities = 54/129 (41%), Positives = 82/129 (63%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           K IAL+AHD  K  ++ +V  H+  L +  L AT TTG LI+   G+ V  MLSGP+GGD
Sbjct: 2   KTIALIAHDKKKSEMLEFVGHHKDFLAKFHLIATRTTGTLINDTFGLGVETMLSGPLGGD 61

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA ++ G++D ++F  DPL + PH+PD+ ALLRL  V ++P+ATN  +A  ++    
Sbjct: 62  QQIGARVAVGEVDYVVFLRDPLTSQPHEPDINALLRLCDVHDVPLATNRKSAHILLAYAA 121

Query: 132 FNDAVDILI 140
            ++  +   
Sbjct: 122 AHEGDEPAE 130


>UniRef50_Q2RSM7 Methylglyoxal synthase n=1 Tax=Rhodospirillum rubrum ATCC 11170
           RepID=Q2RSM7_RHORT
          Length = 155

 Score =  180 bits (457), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 65/149 (43%), Positives = 84/149 (56%), Gaps = 5/149 (3%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAMLSG 66
            P R  I LVAHD  K+ +  WV  +  +L  H L ATGTT  ++       ++  + SG
Sbjct: 7   TPPRMTIGLVAHDGQKRAMGQWVAANATVLGHHALVATGTTARVLKEQNPTFDITGLKSG 66

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P GGDQQ+GALI+EG +D LIFF DP+   PHD DVKAL+RLA V  IP A N ATAD +
Sbjct: 67  PFGGDQQLGALIAEGHLDCLIFFVDPMEPQPHDVDVKALIRLAQVHEIPAACNRATADLM 126

Query: 127 IQSPHFN----DAVDILIPDYQRYLADRL 151
           I SP F      +       +  Y   ++
Sbjct: 127 ITSPLFGVLRAGSFPPAEERFAVYANRKV 155


>UniRef50_Q10YJ6 Cyclic nucleotide-binding protein n=2 Tax=Bacteria
           RepID=Q10YJ6_TRIEI
          Length = 322

 Score =  180 bits (456), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 52/122 (42%), Positives = 85/122 (69%), Gaps = 1/122 (0%)

Query: 7   TLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA-MLS 65
           ++ + K++AL+AH+  K  L+ +V+ H  L+ +  L ATGTTG L+ +ATG+ ++  + S
Sbjct: 148 SVDSTKYLALIAHNEMKSSLVEFVKEHIKLITKFPLVATGTTGLLLHQATGVVLSRKVKS 207

Query: 66  GPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADF 125
           GP+GGDQ +G++IS   I  ++FF DPL++ PH  D++AL RL  V+ +P+ATN +TA  
Sbjct: 208 GPLGGDQAIGSMISTDNICGVLFFRDPLSSHPHHADIEALSRLCDVYQVPLATNPSTAKA 267

Query: 126 II 127
           I+
Sbjct: 268 IL 269


>UniRef50_Q8UIV6 Methylglyoxal synthase n=8 Tax=Alphaproteobacteria RepID=MGSA_AGRT5
          Length = 127

 Score =  180 bits (456), Expect = 2e-44,   Method: Composition-based stats.
 Identities = 61/122 (50%), Positives = 85/122 (69%), Gaps = 1/122 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAMLSG 66
           +  ++ IAL+AHD  K  +  +   HQ +L    + ATGTTG  +  A  G+ V  + SG
Sbjct: 1   MEGQRCIALIAHDEKKDDMADFARHHQKVLASFRIVATGTTGGRVQEACPGLEVIRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GA+I+ G++D+LIFF DPL A+PHD DVKAL RLATV++IP+A N ATA+ +
Sbjct: 61  PLGGDQQIGAMIATGEVDMLIFFTDPLTAMPHDVDVKALTRLATVYDIPMALNRATAENL 120

Query: 127 IQ 128
           I 
Sbjct: 121 ID 122


>UniRef50_P58761 Methylglyoxal synthase n=6 Tax=Bacteria RepID=MGSA_TRESO
          Length = 158

 Score =  175 bits (445), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 55/140 (39%), Positives = 80/140 (57%), Gaps = 6/140 (4%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA-----TGMNVNAMLSGP 67
            IALVAHD+ K  ++ W   +  +L QH L+ TGTTG L+  +        ++  M SGP
Sbjct: 6   RIALVAHDNRKADIVDWALNNAEMLSQHRLFGTGTTGTLVRESFMKRGIASDITCMHSGP 65

Query: 68  MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
           MGGD ++ AL+   +ID  +FF D LN  PH+ D++ LLR   + NIP+A N  +AD +I
Sbjct: 66  MGGDAEIAALVVRKEIDFAVFFIDDLNPQPHEADIQMLLRQCRIHNIPIACNRYSADLMI 125

Query: 128 QSPHFNDA-VDILIPDYQRY 146
            S  ++DA      P Y  +
Sbjct: 126 TSSLWDDAGYVPKDPIYAPF 145


>UniRef50_Q72HP3 Methylglyoxal synthase n=3 Tax=Bacteria RepID=MGSA_THET2
          Length = 126

 Score =  175 bits (444), Expect = 4e-43,   Method: Composition-based stats.
 Identities = 55/116 (47%), Positives = 83/116 (71%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           K +AL+AHD  K  ++++  RH+ +L ++ L ATGTTG  I  ATG+ V  +LSGP+GGD
Sbjct: 2   KALALIAHDAKKDEMVAFCLRHKDVLARYPLLATGTTGARIQEATGLAVERVLSGPLGGD 61

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
            Q+GA ++EGK+  ++F  DPL A PH+PDV+AL+R+  V  +P+ATN+  A+ +I
Sbjct: 62  LQIGARVAEGKVLAVVFLQDPLTAKPHEPDVQALMRVCNVHGVPLATNLVAAEALI 117


>UniRef50_C4ZA41 Methylglyoxal synthase n=10 Tax=Firmicutes RepID=C4ZA41_EUBR3
          Length = 131

 Score =  175 bits (443), Expect = 5e-43,   Method: Composition-based stats.
 Identities = 52/123 (42%), Positives = 80/123 (65%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +I LVAHD  K+++ ++   ++ +L ++ LYATGTTG LI     ++V+  L+G +GG 
Sbjct: 1   MNIGLVAHDSKKKLMQNFCIAYRGILSKNNLYATGTTGRLIEEVANLSVHKYLAGHLGGI 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA I    ID++IF  DPL   PH+P+V ++ R+    NIP+ATN+ATA+ +I S  
Sbjct: 61  QQLGAQIEHNDIDLVIFLRDPLKPKPHEPEVNSIFRICDEHNIPLATNLATAELLILSLD 120

Query: 132 FND 134
             D
Sbjct: 121 RGD 123


>UniRef50_Q55452 Uncharacterized protein sll0036 n=7 Tax=Bacteria RepID=Y036_SYNY3
          Length = 433

 Score =  173 bits (438), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 1/139 (0%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
           HIAL+AHD+ K  L+++V++H+ L  ++ L ATG TG L+   TG+ V+ + SGP+GGD 
Sbjct: 4   HIALIAHDNKKDALVNFVQQHKSLFSRYDLIATGQTGELVRNKTGLAVDTVFSGPLGGDT 63

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           Q+   I +G I  +IF  DPL A PH+PD++ LLRL  V+N+P+A N+ATA  +I+    
Sbjct: 64  QIATQIIDGTIAAVIFLIDPLYAQPHEPDIRTLLRLCEVYNVPLAINLATAKAVIKLLGK 123

Query: 133 ND-AVDILIPDYQRYLADR 150
                 I  P   +   +R
Sbjct: 124 TKTGHLIFNPVAGQGNVER 142


>UniRef50_C3MBY3 Methylglyoxal synthase n=5 Tax=Alphaproteobacteria RepID=MGSA_RHISN
          Length = 126

 Score =  173 bits (438), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 62/122 (50%), Positives = 85/122 (69%), Gaps = 1/122 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAMLSG 66
           +  RK +AL+AHD  K  L ++ + H+  L    + ATGTTG  +  A  G++V  + SG
Sbjct: 1   MADRKCLALIAHDQKKNDLAAFAKAHEATLSGWKIVATGTTGGRVLDACPGLDVTRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GALI+ G +D LIFF DPL A+PHD DVKAL+RLA V++IP+A N ATA+ +
Sbjct: 61  PLGGDQQIGALIATGDVDCLIFFVDPLTAMPHDVDVKALMRLAIVYDIPMALNRATAEQL 120

Query: 127 IQ 128
           I 
Sbjct: 121 ID 122


>UniRef50_A3MI51 Methylglyoxal synthase n=96 Tax=Bacteria RepID=MGSA_BURM7
          Length = 130

 Score =  170 bits (430), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 55/124 (44%), Positives = 82/124 (66%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
           +   IAL+AHD  K  +++    ++  L Q  L ATGTTG  I++A G++V   LSGP+G
Sbjct: 2   STPRIALIAHDAKKDDIVALAGAYRATLAQCRLVATGTTGGRIAQAHGLDVERKLSGPLG 61

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GD Q+GA +++G++D++IF  DP+ A PHDPD+ AL+R   V ++PVATNVATA  ++  
Sbjct: 62  GDLQIGAELADGRVDIVIFLRDPMTAQPHDPDITALVRACDVHDVPVATNVATARVLLDD 121

Query: 130 PHFN 133
               
Sbjct: 122 LARR 125


>UniRef50_C1MXR9 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MXR9_9CHLO
          Length = 281

 Score =  168 bits (427), Expect = 4e-41,   Method: Composition-based stats.
 Identities = 50/140 (35%), Positives = 79/140 (56%), Gaps = 2/140 (1%)

Query: 6   RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV-NAML 64
           +     K +ALVAH+H K  L+ +V  +        +  TG+TG+++    G+ + + + 
Sbjct: 118 KKTTETKLVALVAHNHMKAPLLHFVASNMDFFSTVSIVTTGSTGSVLESNLGLTITHKVS 177

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
           SGP+GGDQ++G + S  ++    FF DPL+A PHD D+KAL R+  V N+PVATN AT  
Sbjct: 178 SGPLGGDQEIGGMASLNQVGGAFFFIDPLSAHPHDDDIKALCRICNVHNVPVATNPATGK 237

Query: 125 FIIQSPHFNDAVDILIPDYQ 144
            ++ +   ND       D +
Sbjct: 238 GLVYAFL-NDEYMKSTLDLK 256


>UniRef50_B3PXK7 Methylglyoxal synthase n=23 Tax=Bacteria RepID=MGSA_RHIE6
          Length = 126

 Score =  166 bits (420), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 58/121 (47%), Positives = 84/121 (69%), Gaps = 1/121 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTG-NLISRATGMNVNAMLSG 66
           +   K +AL+AHD  K  + ++   ++ LL +  + ATGTTG  ++  A  ++V  + SG
Sbjct: 1   MAGGKCLALIAHDQKKDDMAAFARANRDLLSRWKIVATGTTGGRVLDAAPDLDVTRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GALIS G++D LIFF DPL  +PHD DVKAL+RLA V++IP+A N ATA  +
Sbjct: 61  PLGGDQQIGALISTGEVDALIFFVDPLTPMPHDVDVKALMRLAIVYDIPMALNHATAIKL 120

Query: 127 I 127
           +
Sbjct: 121 L 121


>UniRef50_A5FPH5 Methylglyoxal synthase n=5 Tax=Dehalococcoides RepID=A5FPH5_DEHSB
          Length = 143

 Score =  165 bits (419), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 49/133 (36%), Positives = 75/133 (56%)

Query: 9   PARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM 68
             +  + L+AHD+CK+ ++  +  +  L++ H L AT +TG LI + TG+ V    SGP 
Sbjct: 3   EPKITLGLIAHDNCKKDMVQLIHSYAHLMKGHHLIATRSTGELIQKHTGLPVILKESGPD 62

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
           GG+ Q+G  ++   I  +IF  DPL    H+PDV AL+R+    NIP+ATN ATA  ++ 
Sbjct: 63  GGELQLGGFVASRIIKAVIFLRDPLKRKSHEPDVTALMRICDAHNIPLATNRATAACVLH 122

Query: 129 SPHFNDAVDILIP 141
              F+       P
Sbjct: 123 MALFHPEKLDDTP 135


>UniRef50_A7HN41 Methylglyoxal synthase n=1 Tax=Fervidobacterium nodosum Rt17-B1
           RepID=A7HN41_FERNB
          Length = 119

 Score =  164 bits (416), Expect = 6e-40,   Method: Composition-based stats.
 Identities = 48/99 (48%), Positives = 69/99 (69%)

Query: 29  WVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIF 88
           +V+  + + E+  LYAT +TG +I    G+ VN   SGP GGD Q+G++I  G+ID +IF
Sbjct: 2   FVKEWKNVFERCELYATKSTGKIIEEKIGLKVNKFESGPYGGDLQIGSMIVNGEIDFVIF 61

Query: 89  FWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
             DPL A PH+PDV ALLR+  V N+P+ATN+ATA+ ++
Sbjct: 62  LRDPLTAQPHEPDVSALLRVCDVHNVPLATNLATAEALV 100


>UniRef50_A4J7I4 Methylglyoxal synthase n=1 Tax=Desulfotomaculum reducens MI-1
           RepID=A4J7I4_DESRM
          Length = 139

 Score =  163 bits (412), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 48/114 (42%), Positives = 73/114 (64%)

Query: 17  VAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGA 76
           +A  + K    +  +  Q  L QH L  TGTTG+LI    G++V   +SGP+GGDQQ+G 
Sbjct: 24  LAFSYVKNSENALDKEFQLQLSQHDLIGTGTTGSLIKEKVGLDVTCYMSGPLGGDQQIGG 83

Query: 77  LISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
            I++G++ ++IF  DPL   PH+PD+ AL R+  V NIP+ATN++TA  ++ + 
Sbjct: 84  KIAQGEVGLVIFLRDPLTPQPHEPDINALSRICNVHNIPIATNISTAKVLLNNL 137


>UniRef50_C9L646 Methylglyoxal synthase n=12 Tax=Bacteria RepID=C9L646_RUMHA
          Length = 130

 Score =  162 bits (411), Expect = 3e-39,   Method: Composition-based stats.
 Identities = 44/123 (35%), Positives = 72/123 (58%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            ++ ++AH+  K ++  +   ++ +L +H +YATGTTG  I   T + V+  L G MGGD
Sbjct: 1   MNVGIIAHNSKKALIEDFCIAYKNILAKHEIYATGTTGRRIEEVTNLRVHKFLPGSMGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           +Q   +I  G ID++IFF++P      +PDV  +      +NIP+ATN+ATA+ +I    
Sbjct: 61  KQFTEMIERGDIDMVIFFYNPAMIDGTEPDVYQISGCCDQYNIPIATNIATAESLILGLE 120

Query: 132 FND 134
             D
Sbjct: 121 QGD 123


>UniRef50_A5FB35 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A5FB35_FLAJ1
          Length = 133

 Score =  157 bits (397), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 47/118 (39%), Positives = 75/118 (63%), Gaps = 3/118 (2%)

Query: 14  IALVAHDHCKQMLMSWVERHQPLL--EQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           IA++AHD  K  L+ ++ +++ +L  E+  L  TGTTG   + A G     MLSGP+GGD
Sbjct: 12  IAIIAHDGKKADLIDFLIKNEAVLHNEKIRLIGTGTTGGK-AEAAGFKTQRMLSGPLGGD 70

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
            Q+   ++EG   ++ FF DPL++ PH+ D+  L+R+  V N+P+ATN ATA  ++ +
Sbjct: 71  AQIAGRVAEGITQMVFFFKDPLSSHPHEADINMLIRVCDVHNVPLATNEATAQLLLDA 128


>UniRef50_B0C5A3 Putative uncharacterized protein n=1 Tax=Acaryochloris marina
           MBIC11017 RepID=B0C5A3_ACAM1
          Length = 430

 Score =  152 bits (385), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 49/141 (34%), Positives = 77/141 (54%), Gaps = 1/141 (0%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGG 70
              IAL+AH+  K  +++ V+R+  LL ++++ AT  TG  I  AT + V  ++S   GG
Sbjct: 2   PNSIALIAHESKKNDIVTLVQRYHSLLNRYLIVATPDTGKWIQDATNLTVETVVSEADGG 61

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS- 129
             Q+ A +   ++  +IF  D +N     PDV+ALLR+   + +P+ATN+ATA+  IQ  
Sbjct: 62  LLQIAARLVSSEVVGVIFLMDTINVPSQLPDVQALLRVCNRYEVPLATNIATAELAIQGV 121

Query: 130 PHFNDAVDILIPDYQRYLADR 150
               DA  I  P   +   DR
Sbjct: 122 AKRRDAYLIFNPIAGQGNPDR 142


>UniRef50_Q0FI67 Methylglyoxal synthase n=3 Tax=Rhodobacteraceae RepID=Q0FI67_9RHOB
          Length = 358

 Score =  147 bits (372), Expect = 9e-35,   Method: Composition-based stats.
 Identities = 50/127 (39%), Positives = 72/127 (56%), Gaps = 1/127 (0%)

Query: 6   RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAML 64
               A + IAL AHD  K  L +WV RH   LE H L  TG TG +I+ A   +++  + 
Sbjct: 227 MRSTAPRRIALAAHDTRKAHLRAWVSRHAAALEGHRLVCTGGTGQMIAEAAPQLSLRRLQ 286

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
            G  GGDQQ+GA+I+ G++D +IFF DP      + D++AL RLA + + P+A   + AD
Sbjct: 287 RGSRGGDQQLGAMIATGELDAVIFFADPTVPHGGEADLRALTRLAVLHDTPLALGPSGAD 346

Query: 125 FIIQSPH 131
            I  +  
Sbjct: 347 MIATALL 353


>UniRef50_B4SH52 Methylglyoxal synthase-like protein n=2 Tax=cellular organisms
           RepID=B4SH52_PELPB
          Length = 328

 Score =  143 bits (361), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 41/131 (31%), Positives = 63/131 (48%), Gaps = 6/131 (4%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHV-LYATGTTGNLISRATGMNV----NAML 64
               IAL+AHD  K  ++ +   H+  L Q   + ATGTTG  ++ AT   +        
Sbjct: 190 EEMTIALIAHDDMKPRMVEFAVDHEYELGQFCAILATGTTGREVAAATNRTIGNKMIRYH 249

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWN-IPVATNVATA 123
           SGP GGD ++   I  G  DV+IFF DPL+  PH  D++ +++   V + + + TN   A
Sbjct: 250 SGPKGGDIEIATAILYGHCDVVIFFVDPLSPHPHIDDIRVVVQACMVSDRVVMITNEMHA 309

Query: 124 DFIIQSPHFND 134
              +       
Sbjct: 310 REFMTRAVRGK 320


>UniRef50_B7S3K0 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7S3K0_PHATR
          Length = 314

 Score =  143 bits (360), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 38/143 (26%), Positives = 71/143 (49%), Gaps = 8/143 (5%)

Query: 9   PARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA-----M 63
              + +ALV+H+  K  +  +V  ++ +L++  L  T +T  ++S     + +       
Sbjct: 146 SEMRCLALVSHNRMKAAMKEFVTINKNILKKFCLTGTQSTMKMLSEVFKGDSSVVFGPSC 205

Query: 64  LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
            SGP+GGD ++ AL+  G++  ++FF DPL+A  H  D+  L R A V N  +     +A
Sbjct: 206 TSGPLGGDAELAALLCRGRLGGILFFEDPLSAHAHQADIHCLCRQAQVHNTMICATTTSA 265

Query: 124 DFI---IQSPHFNDAVDILIPDY 143
             +   ++S    +    LIP +
Sbjct: 266 LMMMHVLRSALQGNGRPELIPSF 288


>UniRef50_B2IW98 Forkhead-associated protein n=1 Tax=Nostoc punctiforme PCC 73102
           RepID=B2IW98_NOSP7
          Length = 664

 Score =  140 bits (353), Expect = 2e-32,   Method: Composition-based stats.
 Identities = 36/120 (30%), Positives = 63/120 (52%), Gaps = 1/120 (0%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM-GG 70
           ++I L+AH+  K  L  +V +HQ    Q       + G ++ +  G+ ++     P+ GG
Sbjct: 542 RNIVLIAHESKKSELAEFVSQHQEFFSQSFTITWPSVGEVLHQQAGITISQQTPAPISGG 601

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
            Q + +L+  G+I  +IF  D L   P   + +ALLRL T+  + +ATN+ TA+ I+   
Sbjct: 602 YQTIASLVGAGEILAVIFLRDLLQPQPGQANEEALLRLCTINQVLLATNLPTAEAIVHYL 661


>UniRef50_B5VUE7 Diacylglycerol kinase catalytic region n=2 Tax=Arthrospira
           RepID=B5VUE7_SPIMA
          Length = 444

 Score =  133 bits (334), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 40/122 (32%), Positives = 66/122 (54%), Gaps = 2/122 (1%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
            IAL+AHD  ++ L+S+VE +   L  + L A   T   + + TG+ V  + S   GGD 
Sbjct: 4   TIALIAHDSQREELVSFVEENTVALSFYELIAPERTAQYLLQGTGVEVQVLSSLHHGGDI 63

Query: 73  QVGALIS-EGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           ++   I  E +I  +IFF DP   +   P+++ L+R   + N+P+ATN ATA  ++    
Sbjct: 64  ELAYRILQETEIAAVIFFLDPGFNLS-SPEIQVLIRACNLQNVPLATNRATARAMLSGLT 122

Query: 132 FN 133
            +
Sbjct: 123 RS 124


>UniRef50_A0YM60 Putative uncharacterized protein n=1 Tax=Lyngbya sp. PCC 8106
           RepID=A0YM60_9CYAN
          Length = 265

 Score =  129 bits (325), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 2/121 (1%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM-- 68
           RK++ L+A +     L+ WV++   +L    ++A       + +   +NV  +++  +  
Sbjct: 143 RKYMILMADETKMSDLLDWVQKEIDILYNIPIFAPEWVAQSLQQNINLNVKQVINSNVLV 202

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
           GG   +GA I  G I  ++ F DPL   P+   + A+LRL     +  ATN+ TA  I+ 
Sbjct: 203 GGSDTIGAQIILGNIKAVVCFRDPLARRPNRASIDAILRLCDASQVICATNIQTARAILT 262

Query: 129 S 129
           +
Sbjct: 263 A 263


>UniRef50_D0J1U7 Methylglyoxal synthase n=3 Tax=Comamonadaceae RepID=D0J1U7_COMTE
          Length = 291

 Score =  128 bits (322), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 36/126 (28%), Positives = 58/126 (46%), Gaps = 11/126 (8%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVL-YATGTTGNLISRATGMN--------V 60
             + +AL+AHD  K  ++ +   +  LL ++     TGTTG  ++              V
Sbjct: 155 ENQTLALIAHDAMKPTMLDFAAHNFELLSRYRRRVGTGTTGQKLNEMAWSKGWPADKPWV 214

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLAT--VWNIPVAT 118
           +   SGP+GGD Q+  L+ E +    IFF DP  A  H+ D++ L R  T    +   +T
Sbjct: 215 DRYNSGPLGGDAQIADLVLEKRCHRAIFFEDPHVARQHEADIQLLERAVTTVTHDAVCST 274

Query: 119 NVATAD 124
           +   A 
Sbjct: 275 SPQVAQ 280



 Score = 38.3 bits (88), Expect = 0.082,   Method: Composition-based stats.
 Identities = 24/112 (21%), Positives = 41/112 (36%), Gaps = 9/112 (8%)

Query: 47  TTGNLISRATGMNVNAMLSGPMGGDQQVGALIS-----EGKIDVLIFFWDPLNAVPHDPD 101
           T  +++    G+       G  GG  ++ A +      E  +D  I+  DP++     P+
Sbjct: 50  TAASMLQGYKGLV--RYPYGREGGLMRLVAEVVGMEGDERTLDGAIYLMDPVDPSSIFPE 107

Query: 102 VKALLRLATVWNIPVATNVATADFIIQS--PHFNDAVDILIPDYQRYLADRL 151
             AL R   +   P  + VA+    I+    H   A D     +  Y    L
Sbjct: 108 ALALKRQCVIHGKPFLSTVASTRDWIEMERIHAGLARDRNADRFHDYENQTL 159


>UniRef50_A3YU56 Methylglyoxal synthase n=2 Tax=Synechococcus RepID=A3YU56_9SYNE
          Length = 434

 Score =  116 bits (291), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 4/141 (2%)

Query: 14  IALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISR---ATGMNVNAMLSGPMGG 70
           IAL+A     + L+ W+E+HQ LLE   L A       ++    ++G+ V+ + +   GG
Sbjct: 5   IALLASAGSNERLLGWLEQHQVLLEGFPLLAPAELVLALAEDQRSSGLKVSPLATLAAGG 64

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
           D Q+   +  G +  ++FF DP   +   PD++ LLR   +  IP+A N ATA   ++  
Sbjct: 65  DIQIAERVLAGAVGAVLFFVDPATTLATTPDLRLLLRTCALAGIPLALNEATATLALRGL 124

Query: 131 HFND-AVDILIPDYQRYLADR 150
             +  A  I  P   +   ++
Sbjct: 125 GRSRLAYLIFNPVAGQGEPNQ 145


>UniRef50_A5FYW1 Methylglyoxal synthase-like protein n=4 Tax=Proteobacteria
           RepID=A5FYW1_ACICJ
          Length = 318

 Score =  111 bits (279), Expect = 5e-24,   Method: Composition-based stats.
 Identities = 40/121 (33%), Positives = 55/121 (45%), Gaps = 22/121 (18%)

Query: 9   PARKHIALVAHDHCKQMLMSWVERHQPLLEQH-VLYATGTTGNLIS-------------- 53
            A + I L+AHD  K +++ +  RH  LL +     ATGTTG L++              
Sbjct: 169 TATETIGLIAHDTQKPVMLDFARRHHALLSRFGRRLATGTTGGLLNGTVPARLRAETATL 228

Query: 54  ------RATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLR 107
                    G    A  SGP GGD Q+   + EG+   LIFF DP  A  H+ D++ L R
Sbjct: 229 LPLLPPAVPGWT-TAFQSGPRGGDAQIAEEVLEGRCRRLIFFEDPHVAREHEADIQLLER 287

Query: 108 L 108
            
Sbjct: 288 A 288



 Score = 53.3 bits (127), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 29/127 (22%), Positives = 51/127 (40%), Gaps = 14/127 (11%)

Query: 11  RKHIALVAHDHCKQM----LMSWVERHQPLLEQ--HVLYATGTTGNLISRA---TGMNVN 61
           R  I + A    +      L   +    P L      L+A G T + I  +    G    
Sbjct: 11  RLRIGIAASAAMRSSEVSPLFGLLRDFAPFLSSPAVALHAVGATCDAILASGLLAGNPPA 70

Query: 62  AMLSGPMGGDQQVGALI---SEGK--IDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPV 116
            +     GG   + +++   +EG+  +D +I+  DP++ +   P+++AL R   V   P 
Sbjct: 71  RLRPAREGGVITLTSMVVPDAEGRAALDFVIYLIDPVDPIGVFPEMQALKRQCVVHGRPF 130

Query: 117 ATNVATA 123
            TN   A
Sbjct: 131 LTNRGAA 137


>UniRef50_A6SWW2 Uncharacterized conserved protein n=12 Tax=cellular organisms
           RepID=A6SWW2_JANMA
          Length = 315

 Score =  110 bits (275), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 42/107 (39%), Positives = 58/107 (54%), Gaps = 11/107 (10%)

Query: 14  IALVAHDHCKQMLMSWVERHQPLLEQHVL-YATGTTGNLIS--------RATGMN-VNAM 63
           IA++AHD  K  ++   ERH  LL+Q     ATGTTG+L++           G N V   
Sbjct: 177 IAMIAHDAMKGRMLEIAERHFDLLDQFGFRCATGTTGSLLNKLAQKIKGEEAGRNWVKPY 236

Query: 64  LSGPMGGDQQVGALISEG-KIDVLIFFWDPLNAVPHDPDVKALLRLA 109
           LSGPMGGD Q+  LI +  +   ++F  DP  A  H+ D++ L R A
Sbjct: 237 LSGPMGGDAQIAELILDKDQCRRVLFLEDPHVARQHEADIQLLERAA 283



 Score = 41.0 bits (95), Expect = 0.013,   Method: Composition-based stats.
 Identities = 13/69 (18%), Positives = 30/69 (43%), Gaps = 4/69 (5%)

Query: 60  VNAMLSGPMGGDQQVGALISE----GKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIP 115
           +     G  GG  ++ + + +     ++D +++  DP++     P+  AL R   +   P
Sbjct: 80  IERFPYGRHGGLMKLVSRVVDTDPARRLDAVMYLMDPVDPSSIFPEAVALKRQCVIHGKP 139

Query: 116 VATNVATAD 124
             + +A A 
Sbjct: 140 FLSTLAGAR 148


>UniRef50_Q05TV7 Methylglyoxal synthase n=1 Tax=Synechococcus sp. RS9916
           RepID=Q05TV7_9SYNE
          Length = 435

 Score =  106 bits (264), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 4/144 (2%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT---GMNVNAMLSGP 67
              + L A       L +W+  +  LL    L         + R     G+++    +  
Sbjct: 2   PSTLVLNADPVVCPALGTWMTNNTQLLSGFSLLIGEDVIEELKRRHDLGGLSITPCRAIR 61

Query: 68  MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
            GGD  + A I EG+I  L+ F  P +    D   + L+R A + + P+A N ATA  ++
Sbjct: 62  EGGDIAIAARILEGEISGLVHFPAPADQQGRDVLAEPLVRAALLCDRPIALNPATASALL 121

Query: 128 QSPHFN-DAVDILIPDYQRYLADR 150
           Q    +     I  P   +   D+
Sbjct: 122 QGVKRSRRGYLIFNPVAGQGDPDQ 145


>UniRef50_B1YIR9 Carbamoyl-phosphate synthase large chain n=54 Tax=cellular organisms
            RepID=CARB_EXIS2
          Length = 1070

 Score = 87.2 bits (215), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 26/129 (20%), Positives = 57/129 (44%), Gaps = 14/129 (10%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            +   +P    + L   D  KQ ++   +R   L     L AT  T +++    G+ V  +
Sbjct: 928  SGMAIPEHGRVLLTVADQDKQEMLDLAKRFTAL--GFTLLATAGTASVLEEH-GLRVQVV 984

Query: 64   LSGPMGGDQQVGAL---ISEGKIDVLIFFWDPLNAVPH-DPDVKALLRLATVWNIPVATN 119
              G +G +Q  G++   I + +++ +I   + ++       D   + R A   N+   T+
Sbjct: 985  --GKLGSEQ--GSMLEWIEKAEVEYVI---NTMSRDSQVTKDGFIIRRAAAENNVVCLTS 1037

Query: 120  VATADFIIQ 128
            + TA+ +++
Sbjct: 1038 LDTAEALLR 1046


>UniRef50_B8BWS2 Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BWS2_THAPS
          Length = 1354

 Score = 71.4 bits (174), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 15/68 (22%)

Query: 12   KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            + +ALVAH+H +  +  ++E +  +L++  +  T T                +SGP+GGD
Sbjct: 1274 RQLALVAHNHMRPAMKDFIEMYFSILKKFRITGTQT---------------KISGPLGGD 1318

Query: 72   QQVGALIS 79
             QV AL+ 
Sbjct: 1319 AQVAALMC 1326


>UniRef50_UPI0001B41F6C carbamoyl phosphate synthase large subunit n=2 Tax=Listeria
           monocytogenes RepID=UPI0001B41F6C
          Length = 224

 Score = 57.9 bits (139), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 25/128 (19%), Positives = 57/128 (44%), Gaps = 12/128 (9%)

Query: 4   TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
           +  T+     + L   D  K+  +   +R   +     + AT  T + +  A+ + V+ +
Sbjct: 82  SGTTMHDYGTVLLTVADRDKEEAVELAKRFNRI--GFTIMATKGTASTLEEAS-IPVSQV 138

Query: 64  LSGPMGGDQQ-VGALISEGKIDVLIFFWDPLNA--VPHDPDVKALLRLATVWNIPVATNV 120
               +G +Q+ +   I  G++ +++   + L     P + D   + R +    IPV T++
Sbjct: 139 K--KIGENQETLIDYIRNGQVTLVV---NTLTTGKRP-ERDGFQIRRESVENGIPVCTSL 192

Query: 121 ATADFIIQ 128
            TA+ I++
Sbjct: 193 DTAEAILR 200


>UniRef50_C9KKE3 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Mitsuokella
            multacida DSM 20544 RepID=C9KKE3_9FIRM
          Length = 1065

 Score = 56.8 bits (136), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 24/130 (18%), Positives = 48/130 (36%), Gaps = 8/130 (6%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            +   +P +  I     D  K+ +    +    L     + AT  T   I ++ G++   +
Sbjct: 920  SGIHVPTKGCILFTVADKDKEEMKQLAKAFSEL--GFEICATEGTAKAI-QSMGIDAEVV 976

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP-DVKALLRLATVWNIPVATNVAT 122
                      +  +I  GKI+++I   + L    H   D   + R      I   T++ T
Sbjct: 977  GKVHERSSDII-QMIKNGKINMVI---NTLTQGKHSAKDGFKIRRATVEHGIACLTSLDT 1032

Query: 123  ADFIIQSPHF 132
            A  +++   F
Sbjct: 1033 AWEVLRVLSF 1042


>UniRef50_B9KXM5 Carbamoyl-phosphate synthase large chain n=794 Tax=cellular organisms
            RepID=CARB_THERP
          Length = 1078

 Score = 52.2 bits (124), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 9/124 (7%)

Query: 20   DHCKQMLMSWVERHQPLLE-QHVLYATGTTGNLISRATGMNVNAMLSGPMG-GDQQVGAL 77
            D+ K   +      + LL   H L AT  T   + RA G+ V  +    +G G   V  +
Sbjct: 950  DNDKSAGVELA---RGLLALGHPLVATEGTARYL-RAHGVPVE-LTVAHIGHGHPDVLEV 1004

Query: 78   ISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVD 137
            I E K+  +I    P        D   + R A    IP  T++ TA  ++++        
Sbjct: 1005 ILERKVRGVI--NTPGRDEGTIQDGFLIRRAAVERGIPCLTSLDTARALVRALLGGGTSF 1062

Query: 138  ILIP 141
             + P
Sbjct: 1063 SVQP 1066


>UniRef50_C9LZI0 Carbamoyl-phosphate synthase large subunit chain n=1
           Tax=Lactobacillus helveticus DSM 20075
           RepID=C9LZI0_LACHE
          Length = 202

 Score = 51.4 bits (122), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 30/134 (22%), Positives = 61/134 (45%), Gaps = 19/134 (14%)

Query: 6   RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLS 65
             LP   ++ L   D  K+ ++   +R   +   + ++AT  T N + +   ++V  +  
Sbjct: 70  MQLPENGNVLLTIEDRDKEKILPIAKRFARI--GYRIFATKGTANFLKKN-DLHVELVTK 126

Query: 66  GPMGGDQQ----VGALISEGKIDVLIFFWDPLNAVPHD----PDVKALLRLATVWNIPVA 117
                D+Q    +   + +GKID++I      N + HD     D   + ++A   N+P+ 
Sbjct: 127 VHE--DEQAYDNILNELRDGKIDLVI------NTMGHDIEKNSDGFIIRQMAIQQNVPLL 178

Query: 118 TNVATADFIIQSPH 131
           T + TAD +++S  
Sbjct: 179 TALDTADALLKSLE 192


>UniRef50_A5D508 Carbamoyl-phosphate synthase large chain n=178 Tax=cellular organisms
            RepID=CARB_PELTS
          Length = 1083

 Score = 50.6 bits (120), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 27/141 (19%), Positives = 52/141 (36%), Gaps = 20/141 (14%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M      + +   +     D  K   +S    +  L   + L+AT  T   +    G+ V
Sbjct: 927  MRAAGLKVASGGRVVFSVADRDKAEAVSIAGEYAAL--GYTLHATPGTARAL-EKAGLEV 983

Query: 61   NAM-LSGPMGGDQQVGALISEGKIDVLIFFWDPLNA--VPHDPDVKALLRLATVWNIPVA 117
              + ++ P+        LI  G + ++I   +      VP  P    L R A  + +P  
Sbjct: 984  EVVEITDPV-------PLIRSGTVGLII---NTPTRGKVPGRP-GFLLRRTAAEYRVPCL 1032

Query: 118  TNVATADFI---IQSPHFNDA 135
            T++ TA  +   ++S  +   
Sbjct: 1033 TSLDTARALAMVLRSVRWGGE 1053


>UniRef50_B2A170 Carbamoyl-phosphate synthase large chain n=3 Tax=Bacteria
            RepID=CARB_NATTJ
          Length = 1106

 Score = 49.8 bits (118), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 34/154 (22%), Positives = 62/154 (40%), Gaps = 15/154 (9%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  +  ++     + +   D  K+ +   VER Q L     ++AT  T   +    G++V
Sbjct: 960  MLASGFSINLNGGVLVTVADRDKEAVRPLVERFQKL--GLKIFATSGTAEFLRNQ-GIDV 1016

Query: 61   NAMLSGPMGGDQQ--VGALISEGKIDVLIFFWDPLNAVPHDP--DVKALLRLATVWNIPV 116
              +   P   D+   +  LI EG+I+ +I   +       +P  D   + R A    IP 
Sbjct: 1017 EQV---PKIVDESPNIIDLIREGQINYVI---NTFTI-GKEPARDGFKIRRAAVENGIPC 1069

Query: 117  ATNVATADFIIQSPHFND-AVDILIPDYQRYLAD 149
             T++ TA  ++ +    D      +   Q YL +
Sbjct: 1070 LTSLDTASALLTAMESLDRGESKQVKSLQDYLKE 1103


>UniRef50_O67233 Carbamoyl-phosphate synthase large chain, C-terminal section n=28
           Tax=Bacteria RepID=CARB2_AQUAE
          Length = 537

 Score = 49.8 bits (118), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 23/126 (18%), Positives = 49/126 (38%), Gaps = 7/126 (5%)

Query: 4   TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
               LP + ++ +   D  K  ++   +  + L     +YAT  T   +    G+N   +
Sbjct: 394 AGYRLPEKGNLFISVADRDKPKILELAKEFEKL--GFGIYATSGTYKFLKEH-GVNAKRV 450

Query: 64  LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
           L    G    V  +I  G+I ++I   +  +      D   + R    +N+P  T +   
Sbjct: 451 LKVSEG-RPNVVDMIINGEIHLVI---NTPSGKREKSDAYYIRRACVQFNVPYYTTMRAG 506

Query: 124 DFIIQS 129
             ++++
Sbjct: 507 YAVLEA 512


>UniRef50_A6CPS0 Carbamoyl-phosphate synthase large subunit n=2 Tax=Bacteria
           RepID=A6CPS0_9BACI
          Length = 167

 Score = 48.3 bits (114), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 24/128 (18%), Positives = 49/128 (38%), Gaps = 12/128 (9%)

Query: 4   TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
               +     + L   D  K   +   +R   +   + + AT  T +++ R   + V  +
Sbjct: 25  AGMQMKEYGSVLLTVADKDKDEAIGLAKRFVNI--GYQILATKGTADVL-RTADIPVKEV 81

Query: 64  -LSGPMGGDQQVGALISEGKIDVLIFFWDPLNA--VPHDPDVKALLRLATVWNIPVATNV 120
              G  G    +  +I  G+  ++I   + L     P   D   + R +    IP  T++
Sbjct: 82  DKIGSEG--PTLLDVIQSGETQLVI---NTLTKGKQPQR-DGFRIRRESVENGIPCLTSL 135

Query: 121 ATADFIIQ 128
            TA+ I++
Sbjct: 136 DTAEAILK 143


>UniRef50_A2BWE6 Carbamoyl-phosphate synthase, large subunit n=56 Tax=cellular
            organisms RepID=A2BWE6_PROM5
          Length = 1100

 Score = 44.8 bits (105), Expect = 9e-04,   Method: Composition-based stats.
 Identities = 30/126 (23%), Positives = 48/126 (38%), Gaps = 7/126 (5%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            +   +P+     L  +D  K  L         L     L AT  T + +    G+ V+ +
Sbjct: 962  SGNGVPSEGVAFLSTNDLDKDKLEEIARELIVL--GFKLIATKGTASYLL-NLGIEVDEV 1018

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
            L    G    +  LI  G I ++I    P+ +     D   L R A  +NIP  T +  A
Sbjct: 1019 LKVHEG-RPNIEDLIRSGLIQLVI--NTPIGSQAFHDDAY-LRRAALEYNIPTFTTIPGA 1074

Query: 124  DFIIQS 129
               +Q+
Sbjct: 1075 KAALQA 1080


>UniRef50_C6Q1M4 MGS domain protein n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6Q1M4_9CLOT
          Length = 159

 Score = 44.8 bits (105), Expect = 0.001,   Method: Composition-based stats.
 Identities = 30/121 (24%), Positives = 54/121 (44%), Gaps = 11/121 (9%)

Query: 20  DHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALIS 79
           D  K+  +  ++ +Q L      YA+  TGN +    G  ++  +   + GD QV   I 
Sbjct: 41  DVDKKEGIDIIKDYQKL--GFKFYASEGTGNYLK---GNAIDCTI---IDGD-QVSEFIV 91

Query: 80  EGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDIL 139
           +GKI +LI    P      + +   L R A  + +PV T + TA   + + +F  + + +
Sbjct: 92  DGKIKMLI--NTPTRGNNPESEGFKLRRKAAEYRVPVFTCIDTAKIFLTAINFKKSNEKV 149

Query: 140 I 140
            
Sbjct: 150 E 150


>UniRef50_Q9HK17 Carbamoyl-phosphate synthase large chain n=4 Tax=Thermoplasmatales
            RepID=CARB_THEAC
          Length = 1047

 Score = 43.7 bits (102), Expect = 0.002,   Method: Composition-based stats.
 Identities = 27/164 (16%), Positives = 56/164 (34%), Gaps = 25/164 (15%)

Query: 1    MELTTRTLPARKHIA---------------LVAHDHCKQMLMSWVERHQPLLEQHVLYAT 45
            M+ T   +   + +A               +   D  K  ++        L +   LYAT
Sbjct: 891  MKSTGEAMYPGRTLAEALRKSLQRSISSVLITVRDEDKPRIVDIAR--ILLEKGVKLYAT 948

Query: 46   GTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP-DVKA 104
              T   ++   G+    +       + ++  +IS G ID++I   +          D   
Sbjct: 949  AGTSKFLADH-GIPTETLYRVRDRREPRILDMISSGSIDMVI---NTTEMTAGAVRDGFK 1004

Query: 105  LLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLA 148
            + R+  +  IP+  N+  A    ++      V++   +   YL 
Sbjct: 1005 IRRICIMRGIPLIMNINLARAYAEAL---GQVEVDYREIGDYLQ 1045


>UniRef50_D1CBW2 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Thermobaculum
            terrenum ATCC BAA-798 RepID=D1CBW2_THET1
          Length = 1095

 Score = 43.7 bits (102), Expect = 0.002,   Method: Composition-based stats.
 Identities = 24/143 (16%), Positives = 48/143 (33%), Gaps = 11/143 (7%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M       P    + +   DH K   +        +   + L  T  T        G+ V
Sbjct: 947  MIAAGINPPPGGSVLMSIADHEKPEALPLAAALVDM--GYALVCTEGTSTFFEDN-GIRV 1003

Query: 61   NAM--LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP-DVKALLRLATVWNIPVA 117
            N +    G +  D  +  +I   ++ ++I   +  +       D   + R A    IP  
Sbjct: 1004 NQVVHKIGSVRPD--ITDIIRRRQVSLVI---NTPSRSGRTIRDGFEIRRAAAESGIPCL 1058

Query: 118  TNVATADFIIQSPHFNDAVDILI 140
            T++ TA  ++++       +I  
Sbjct: 1059 TSLDTAKSLVKALQRRGDYNIAT 1081


>UniRef50_D1Y1S0 Carbamoyl-phosphate synthase, large subunit n=2 Tax=Bacteria
            RepID=D1Y1S0_9BACT
          Length = 1364

 Score = 41.8 bits (97), Expect = 0.007,   Method: Composition-based stats.
 Identities = 24/135 (17%), Positives = 47/135 (34%), Gaps = 14/135 (10%)

Query: 20   DHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG----GDQQVG 75
            D  K  ++    R   L     LY TG T   +          + S  +G    G++ + 
Sbjct: 958  DRDKPEIVELARRLASL--GCRLYTTGGTAEYLKS------RGIRSASVGKISQGNRDIP 1009

Query: 76   ALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDA 135
             L+ +G++  ++    P ++     D + L   A        T++ TA  ++        
Sbjct: 1010 YLLDQGRVQYVLSTSSPDSSE--RADAQVLRSKAIERRAACMTSLDTARALVDCMVSGYD 1067

Query: 136  VDILIPDYQRYLADR 150
               +      +L DR
Sbjct: 1068 EGNVELVDMAHLPDR 1082


>UniRef50_Q9CKV0 Carbamoyl-phosphate synthase large chain n=6 Tax=cellular organisms
            RepID=CARB_PASMU
          Length = 1068

 Score = 41.8 bits (97), Expect = 0.007,   Method: Composition-based stats.
 Identities = 24/120 (20%), Positives = 47/120 (39%), Gaps = 8/120 (6%)

Query: 8    LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
            +P    + L  +D  K  L+    + Q     + L AT  T   +    G+ V  +    
Sbjct: 933  IPKTGKVFLSVNDADKPRLLPIARQLQE--SGYGLCATLGTAKFLREH-GVAVQIINKVR 989

Query: 68   MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP-DVKALLRLATVWNIPVATNVATADFI 126
             G    +   I  G+I ++I   + ++ +     D  A+ R A    + + T +A A+ +
Sbjct: 990  EG-RPNIVDAIKNGEIAMVI---NTVSGLAETVTDGHAIRRSALQQKVFLQTTLAGAEAL 1045


>UniRef50_O93937 Aspartate carbamoyltransferase n=344 Tax=cellular organisms
            RepID=PYR1_EMENI
          Length = 2275

 Score = 41.4 bits (96), Expect = 0.008,   Method: Composition-based stats.
 Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 19/154 (12%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            T   LP R  +  +     K  ++  + + + +     L+AT  T + +    G+ V  +
Sbjct: 1394 TGFKLPKRNILLSIGSYKEKMEMLPSIIKLRDV--GFELFATSGTADFLKEN-GVPVKYL 1450

Query: 64   LSGPMGGDQQVGAL------ISEGKIDVLI------FFWDPLNAVPHDPDVKALLRLATV 111
               P G D+ + +       ++   ID+ I       F  P N +          R+A  
Sbjct: 1451 EILP-GEDEDIKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYMSK---GYRTRRMAVD 1506

Query: 112  WNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
            +  P+ TNV  A  +I++   + A+++   DYQ 
Sbjct: 1507 YQTPLVTNVKNAKILIEAIARHYALNVQTIDYQT 1540


>UniRef50_P07259 Aspartate carbamoyltransferase n=65 Tax=cellular organisms
            RepID=PYR1_YEAST
          Length = 2214

 Score = 41.0 bits (95), Expect = 0.011,   Method: Composition-based stats.
 Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 18/148 (12%)

Query: 10   ARKHIAL-VAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM 68
             +K+I L +     KQ L+S V++   +   + L+AT  T + +S   G+ V  +     
Sbjct: 1359 PKKNILLSIGSYKEKQELLSSVQKLYNM--GYKLFATSGTADFLSEH-GIAVQYLEVLNK 1415

Query: 69   GGDQQ-----VGALISEGKIDVLI------FFWDPLNAVPHDPDVKALLRLATVWNIPVA 117
              D Q     +   ++  +ID+ I       F  P + V          RLA  +++P+ 
Sbjct: 1416 DDDDQKSEYSLTQHLANNEIDLYINLPSANRFRRPASYVSK---GYKTRRLAVDYSVPLV 1472

Query: 118  TNVATADFIIQSPHFNDAVDILIPDYQR 145
            TNV  A  +I++   N  +D+   D Q 
Sbjct: 1473 TNVKCAKLLIEAISRNITLDVSERDAQT 1500


>UniRef50_Q58776 Carbamoyl-phosphate synthase large chain, C-terminal section n=10
           Tax=cellular organisms RepID=CARB2_METJA
          Length = 618

 Score = 40.6 bits (94), Expect = 0.014,   Method: Composition-based stats.
 Identities = 21/126 (16%), Positives = 48/126 (38%), Gaps = 6/126 (4%)

Query: 4   TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
               LP   ++ +   D  K+ ++   ++   L     +YAT  T  ++    G+    +
Sbjct: 474 ANMELPIVGNVFISVRDRDKKHIVDVAKKLHEL--GFTIYATEGTAKVLREN-GIPAILV 530

Query: 64  LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
                  +  +  L+ +GK+ ++I   +  +      D   + R A    IP  T +  A
Sbjct: 531 KKISESPNDNILKLMRDGKMHLII---NTSSGKKAKSDGYYIRRAAVDLGIPYITTIPGA 587

Query: 124 DFIIQS 129
              +++
Sbjct: 588 KAAVKA 593


>UniRef50_A9QP20 Carbamoyl phosphate synthetase ammonia large chain n=3
            Tax=environmental samples RepID=A9QP20_9EURY
          Length = 1122

 Score = 40.2 bits (93), Expect = 0.019,   Method: Composition-based stats.
 Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 4/110 (3%)

Query: 20   DHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALIS 79
            +  K  ++   +  + +     +YAT  T +++  + G++V        G       L+ 
Sbjct: 997  NADKHDVIPLAQELEEM--GFTIYATRGTAHVLRDSGGVDVQTCYRITEGLTPDALDLMR 1054

Query: 80   EGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
            +GKI ++     P N      D   + RLA   NIP  T +A A   +Q+
Sbjct: 1055 QGKIHLI--LNTPRNTGGAVLDGNMMRRLAVELNIPFVTTMAGARMEVQA 1102


>UniRef50_B0U8L9 Carbamoyl-phosphate synthase, large subunit n=3 Tax=Methylobacterium
            RepID=B0U8L9_METS4
          Length = 1157

 Score = 39.4 bits (91), Expect = 0.034,   Method: Composition-based stats.
 Identities = 24/129 (18%), Positives = 46/129 (35%), Gaps = 13/129 (10%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA--TGMNVN 61
            +   +P    + +   D  K  ++  V     +     + ATG T   ++        +N
Sbjct: 1019 SGTQVPRAGTVFVSVRDADKARILPAVRMLAEI--GFAILATGGTQRFLAENGVAATRIN 1076

Query: 62   AMLSG-PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +L G P   D      I  G+I ++    +         D ++L R A +  +P  T +
Sbjct: 1077 KVLEGRPHVVDA-----IKNGEIHLVF---NTTEGAGALSDSRSLRRAALLHKVPYYTTL 1128

Query: 121  ATADFIIQS 129
            A A    + 
Sbjct: 1129 AGAMAAAEG 1137


>UniRef50_Q03WW7 Carbamoyl-phosphate synthase large chain n=115 Tax=Bacteria
            RepID=CARB_LEUMM
          Length = 1059

 Score = 39.4 bits (91), Expect = 0.037,   Method: Composition-based stats.
 Identities = 24/122 (19%), Positives = 46/122 (37%), Gaps = 8/122 (6%)

Query: 7    TLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSG 66
             +P   ++     D  K+  +   +R   L     L+AT  TG  +S    + V  +   
Sbjct: 931  KVPRYGNVLFTVADDDKEEALELAKRFNDL--GFALFATAGTGAYLSDN-DLPVEVLDKI 987

Query: 67   PMGGDQQVGALISEGKIDVLIFFWDPLNAVPH-DPDVKALLRLATVWNIPVATNVATADF 125
                +  V AL  + K+ V+I   +   A    + D + +   A    +P+ T + T   
Sbjct: 988  SESDNNAVAAL-RQQKVQVVI---NTTQADDRAESDGRLIRNAAIENAVPLFTALDTVSA 1043

Query: 126  II 127
             +
Sbjct: 1044 FL 1045


>UniRef50_C3XFR9 Carbamoyl-phosphate synthase subunit large n=1 Tax=Helicobacter bilis
            ATCC 43879 RepID=C3XFR9_9HELI
          Length = 1215

 Score = 39.1 bits (90), Expect = 0.047,   Method: Composition-based stats.
 Identities = 29/144 (20%), Positives = 55/144 (38%), Gaps = 8/144 (5%)

Query: 8    LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
            LP +  I +   +  K+      +  Q +     + AT  T  ++S A G+   A+L   
Sbjct: 1078 LPKKGKIFISLRNSDKKHAAGLAKTLQEI--GFEIVATLGTHKILSEA-GIEAKAVLKVS 1134

Query: 68   MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
             G    +  +I+  +ID++I   +  +     PD + +       NIP  T ++ A    
Sbjct: 1135 EG-RPHINDMIANHEIDMVI---NTSSNKAQ-PDARLIREAVLRANIPYFTTISGAKSAA 1189

Query: 128  QSPHFNDAVDILIPDYQRYLADRL 151
             +   N   +       + L D L
Sbjct: 1190 IAMQANGNDNENTRVSTKALQDYL 1213


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_B7UN42 Methylglyoxal synthase n=174 Tax=Bacteria RepID=...   221   6e-57
UniRef50_B5XY41 Methylglyoxal synthase n=65 Tax=Gammaproteobacte...   214   5e-55
UniRef50_Q4QJW2 Methylglyoxal synthase n=45 Tax=cellular organis...   203   2e-51
UniRef50_Q72NU6 Methylglyoxal synthase n=20 Tax=Bacteria RepID=M...   201   5e-51
UniRef50_B8I1E7 Methylglyoxal synthase n=13 Tax=Firmicutes RepID...   200   1e-50
UniRef50_A4BFH8 Methylglyoxal synthase n=1 Tax=Reinekea blandens...   200   2e-50
UniRef50_Q2SK75 Methylglyoxal synthase n=2 Tax=Gammaproteobacter...   197   9e-50
UniRef50_A9KFK7 Methylglyoxal synthase n=6 Tax=Coxiella burnetii...   197   1e-49
UniRef50_B9MRV5 Methylglyoxal synthase n=158 Tax=cellular organi...   195   4e-49
UniRef50_A0LVE0 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A0...   193   1e-48
UniRef50_C6BZQ4 Methylglyoxal synthase n=7 Tax=Bacteria RepID=MG...   190   1e-47
UniRef50_UPI0001745D5F methylglyoxal synthase n=1 Tax=Verrucomic...   188   4e-47
UniRef50_Q1QX97 Methylglyoxal synthase n=4 Tax=Bacteria RepID=Q1...   188   4e-47
UniRef50_B0KAD1 Methylglyoxal synthase n=27 Tax=cellular organis...   187   1e-46
UniRef50_A4IQ66 Methylglyoxal synthase n=37 Tax=Bacteria RepID=M...   183   2e-45
UniRef50_C1TMX7 Methylglyoxal synthase n=1 Tax=Dethiosulfovibrio...   179   3e-44
UniRef50_A6L618 Methylglyoxal synthase n=34 Tax=Bacteroidales Re...   178   5e-44
UniRef50_B1YKL9 Methylglyoxal synthase n=78 Tax=Bacteria RepID=M...   177   9e-44
UniRef50_C2HDU2 Methylglyoxal synthase n=12 Tax=Enterococcus fae...   175   3e-43
UniRef50_Q55452 Uncharacterized protein sll0036 n=7 Tax=Bacteria...   174   6e-43
UniRef50_D0MG34 Methylglyoxal synthase n=1 Tax=Rhodothermus mari...   174   7e-43
UniRef50_Q3AGN5 Cyclic nucleotide-binding domain (CNMP-BD) prote...   174   8e-43
UniRef50_C9KKW1 Methylglyoxal synthase n=1 Tax=Mitsuokella multa...   173   1e-42
UniRef50_D2BG68 Methylglyoxal synthase n=5 Tax=Dehalococcoides R...   173   2e-42
UniRef50_UPI0000E11027 methylglyoxal synthase n=1 Tax=Rhodobacte...   172   4e-42
UniRef50_Q10YJ6 Cyclic nucleotide-binding protein n=2 Tax=Bacter...   171   7e-42
UniRef50_Q8UIV6 Methylglyoxal synthase n=8 Tax=Alphaproteobacter...   169   2e-41
UniRef50_Q2RSM7 Methylglyoxal synthase n=1 Tax=Rhodospirillum ru...   169   2e-41
UniRef50_C4ZA41 Methylglyoxal synthase n=10 Tax=Firmicutes RepID...   167   1e-40
UniRef50_Q72HP3 Methylglyoxal synthase n=3 Tax=Bacteria RepID=MG...   166   1e-40
UniRef50_C3MBY3 Methylglyoxal synthase n=5 Tax=Alphaproteobacter...   164   1e-39
UniRef50_A3MI51 Methylglyoxal synthase n=96 Tax=Bacteria RepID=M...   161   5e-39
UniRef50_P58761 Methylglyoxal synthase n=6 Tax=Bacteria RepID=MG...   160   1e-38
UniRef50_B3PXK7 Methylglyoxal synthase n=23 Tax=Bacteria RepID=M...   160   1e-38
UniRef50_A5FPH5 Methylglyoxal synthase n=5 Tax=Dehalococcoides R...   158   6e-38
UniRef50_A7HN41 Methylglyoxal synthase n=1 Tax=Fervidobacterium ...   157   1e-37
UniRef50_C9L646 Methylglyoxal synthase n=12 Tax=Bacteria RepID=C...   156   2e-37
UniRef50_A4J7I4 Methylglyoxal synthase n=1 Tax=Desulfotomaculum ...   156   2e-37
UniRef50_C1MXR9 Predicted protein n=1 Tax=Micromonas pusilla CCM...   155   4e-37
UniRef50_B0C5A3 Putative uncharacterized protein n=1 Tax=Acaryoc...   150   2e-35
UniRef50_A5FB35 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A5...   146   3e-34
UniRef50_Q0FI67 Methylglyoxal synthase n=3 Tax=Rhodobacteraceae ...   140   1e-32
UniRef50_B4SH52 Methylglyoxal synthase-like protein n=2 Tax=cell...   136   2e-31
UniRef50_B7S3K0 Predicted protein n=1 Tax=Phaeodactylum tricornu...   133   2e-30
UniRef50_B5VUE7 Diacylglycerol kinase catalytic region n=2 Tax=A...   133   2e-30
UniRef50_B2IW98 Forkhead-associated protein n=1 Tax=Nostoc punct...   129   2e-29
UniRef50_D0J1U7 Methylglyoxal synthase n=3 Tax=Comamonadaceae Re...   121   6e-27
UniRef50_A0YM60 Putative uncharacterized protein n=1 Tax=Lyngbya...   121   8e-27
UniRef50_A3YU56 Methylglyoxal synthase n=2 Tax=Synechococcus Rep...   120   1e-26
UniRef50_Q05TV7 Methylglyoxal synthase n=1 Tax=Synechococcus sp....   118   7e-26
UniRef50_B2A170 Carbamoyl-phosphate synthase large chain n=3 Tax...   112   4e-24
UniRef50_C9KKE3 Carbamoyl-phosphate synthase, large subunit n=1 ...   111   8e-24
UniRef50_UPI0001B41F6C carbamoyl phosphate synthase large subuni...   108   4e-23
UniRef50_O67233 Carbamoyl-phosphate synthase large chain, C-term...   106   2e-22
UniRef50_D1CBW2 Carbamoyl-phosphate synthase, large subunit n=1 ...   105   4e-22
UniRef50_B1YIR9 Carbamoyl-phosphate synthase large chain n=54 Ta...   105   4e-22
UniRef50_A6SWW2 Uncharacterized conserved protein n=12 Tax=cellu...   104   6e-22
UniRef50_Q9HK17 Carbamoyl-phosphate synthase large chain n=4 Tax...   103   3e-21
UniRef50_A5FYW1 Methylglyoxal synthase-like protein n=4 Tax=Prot...   102   3e-21
UniRef50_C9LZI0 Carbamoyl-phosphate synthase large subunit chain...   100   3e-20
UniRef50_A2BWE6 Carbamoyl-phosphate synthase, large subunit n=56...   100   3e-20
UniRef50_B9KXM5 Carbamoyl-phosphate synthase large chain n=794 T...    98   6e-20
UniRef50_C6Q1M4 MGS domain protein n=1 Tax=Clostridium carboxidi...    98   1e-19
UniRef50_A6CPS0 Carbamoyl-phosphate synthase large subunit n=2 T...    97   2e-19
UniRef50_A5D508 Carbamoyl-phosphate synthase large chain n=178 T...    96   3e-19
UniRef50_B8BWS2 Predicted protein n=1 Tax=Thalassiosira pseudona...    66   4e-10

Sequences not found previously or not previously below threshold:

UniRef50_A8V5Q7 Carbamoyl-phosphate synthase large subunit (Frag...    85   5e-16
UniRef50_Q58776 Carbamoyl-phosphate synthase large chain, C-term...    85   5e-16
UniRef50_Q9CKV0 Carbamoyl-phosphate synthase large chain n=6 Tax...    80   2e-14
UniRef50_Q03WW7 Carbamoyl-phosphate synthase large chain n=115 T...    78   6e-14
UniRef50_Q8YQL2 Carbamoyl-phosphate synthase large chain n=44 Ta...    78   9e-14
UniRef50_B0U8L9 Carbamoyl-phosphate synthase, large subunit n=3 ...    77   2e-13
UniRef50_A9QP20 Carbamoyl phosphate synthetase ammonia large cha...    76   3e-13
UniRef50_C3XFR9 Carbamoyl-phosphate synthase subunit large n=1 T...    75   8e-13
UniRef50_UPI0001B44E07 carbamoyl phosphate synthase large subuni...    75   8e-13
UniRef50_Q0TM79 Carbamoyl-phosphate synthase large chain n=94 Ta...    75   9e-13
UniRef50_C0A8Y6 Carbamoyl-phosphate synthase, large subunit n=2 ...    74   1e-12
UniRef50_C0R503 Carbamoyl-phosphate synthase large subunit n=6 T...    72   4e-12
UniRef50_A7HVJ4 Carbamoyl-phosphate synthase, large subunit n=20...    71   7e-12
UniRef50_D1Y1S0 Carbamoyl-phosphate synthase, large subunit n=2 ...    71   8e-12
UniRef50_A9A4K3 Carbamoyl-phosphate synthase, large subunit n=5 ...    69   4e-11
UniRef50_Q3APN7 Carbamoyl-phosphate synthase large subunit n=11 ...    69   5e-11
UniRef50_UPI0001C31DA7 carbamoyl-phosphate synthase, large subun...    69   5e-11
UniRef50_A6LPD9 Carbamoyl-phosphate synthase large chain n=23 Ta...    68   9e-11
UniRef50_C8PAM0 Carbamoyl-phosphate synthase n=4 Tax=Lactobacill...    67   2e-10
UniRef50_C9RNJ8 Carbamoyl-phosphate synthase, large subunit n=7 ...    66   2e-10
UniRef50_Q9KHE9 Carbamoyl phosphate synthetase large subunit (Fr...    66   2e-10
UniRef50_B9L7I5 Carbamoyl-phosphate synthase, large subunit n=7 ...    66   3e-10
UniRef50_C1A4I5 Carbamoyl-phosphate synthase large chain n=223 T...    66   3e-10
UniRef50_P07259 Aspartate carbamoyltransferase n=65 Tax=cellular...    65   5e-10
UniRef50_O93937 Aspartate carbamoyltransferase n=344 Tax=cellula...    65   9e-10
UniRef50_Q2FLD9 Carbamoyl-phosphate synthase large chain n=6 Tax...    64   2e-09
UniRef50_A8F453 Carbamoyl-phosphate synthase large chain n=13 Ta...    64   2e-09
UniRef50_A2QRW1 Contig An08c0170, complete genome n=337 Tax=cell...    63   3e-09
UniRef50_B8GEA3 Carbamoyl-phosphate synthase large chain n=2 Tax...    63   3e-09
UniRef50_UPI000197805F carbamoyl phosphate synthase large subuni...    62   4e-09
UniRef50_O50236 Carbamoyl-phosphate synthase large chain n=3 Tax...    62   6e-09
UniRef50_Q1GA90 Carbamoyl-phosphate synthase, large chain n=28 T...    62   6e-09
UniRef50_UPI00017430FF carbamoyl phosphate synthase large subuni...    61   8e-09
UniRef50_Q8UDE9 Carbamoyl-phosphate synthase large chain n=103 T...    61   1e-08
UniRef50_P31327 Carbamoyl-phosphate synthase [ammonia], mitochon...    61   1e-08
UniRef50_B7G8W8 Predicted protein n=7 Tax=cellular organisms Rep...    61   1e-08
UniRef50_A8JIR0 Carbamoyl phosphate synthase, large subunit n=1 ...    60   2e-08
UniRef50_C0AZ23 Putative uncharacterized protein n=1 Tax=Proteus...    58   1e-07
UniRef50_B3LBP4 Carbamoyl phosphate synthetase, putative n=6 Tax...    57   2e-07
UniRef50_C5JG53 Bifunctional pyrimidine biosynthesis protein pyr...    57   2e-07
UniRef50_C0NSX2 Carbamoyl-phosphate synthase n=3 Tax=cellular or...    56   3e-07
UniRef50_C6XKE0 MGS domain protein n=1 Tax=Hirschia baltica ATCC...    56   4e-07
UniRef50_Q9ZKT2 Carbamoyl-phosphate synthase large chain n=422 T...    56   4e-07
UniRef50_Q17XX3 Carbamoyl-phosphate synthase large chain n=7 Tax...    56   4e-07
UniRef50_Q8IEN3 Carbamoyl phosphate synthetase n=3 Tax=Eukaryota...    55   6e-07
UniRef50_D2LJN2 MGS domain protein n=1 Tax=Rhodomicrobium vannie...    52   6e-06
UniRef50_A9V282 Predicted protein n=2 Tax=cellular organisms Rep...    50   2e-05
UniRef50_C5KGZ1 Putative uncharacterized protein n=1 Tax=Perkins...    49   4e-05
UniRef50_P05990 Dihydroorotase n=643 Tax=cellular organisms RepI...    49   6e-05
UniRef50_B8DTW3 Carbamoyl-phosphate synthase large chain n=400 T...    49   6e-05
UniRef50_B6KSM2 Carbamoyl phosphate synthetase II n=4 Tax=Toxopl...    49   6e-05
UniRef50_Q1RKZ5 IP15551p (Fragment) n=1 Tax=Drosophila melanogas...    48   9e-05
UniRef50_C1TLQ6 Carbamoyl-phosphate synthase, large subunit n=1 ...    48   1e-04
UniRef50_UPI000194C4F6 PREDICTED: similar to carbamoylphosphate ...    43   0.002
UniRef50_B2KDJ0 Carbamoyl-phosphate synthase, large subunit n=10...    43   0.003
UniRef50_D2RG70 MGS domain protein n=1 Tax=Archaeoglobus profund...    41   0.009
UniRef50_D1B6T5 Carbamoyl-phosphate synthase, large subunit n=1 ...    39   0.039
UniRef50_UPI0000384730 COG0313: Predicted methyltransferases n=1...    38   0.070

>UniRef50_B7UN42 Methylglyoxal synthase n=174 Tax=Bacteria RepID=MGSA_ECO27
          Length = 152

 Score =  221 bits (563), Expect = 6e-57,   Method: Composition-based stats.
 Identities = 151/152 (99%), Positives = 152/152 (100%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           MELTTRTLP+RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV
Sbjct: 1   MELTTRTLPSRKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
           NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV
Sbjct: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
           ATADFIIQSPHFNDAVDILIPDYQRYLADRLK
Sbjct: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152


>UniRef50_B5XY41 Methylglyoxal synthase n=65 Tax=Gammaproteobacteria
           RepID=MGSA_KLEP3
          Length = 152

 Score =  214 bits (546), Expect = 5e-55,   Method: Composition-based stats.
 Identities = 136/152 (89%), Positives = 142/152 (93%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           MELTTRTL A+KHIALVAHDHCK MLM WV RHQ LL QHVLYATGTTGNL+SRATG+ V
Sbjct: 1   MELTTRTLSAQKHIALVAHDHCKDMLMKWVARHQALLAQHVLYATGTTGNLVSRATGLEV 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
           NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV
Sbjct: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
           +TADFIIQSPHFN  +DILIPDY RYLA+RLK
Sbjct: 121 STADFIIQSPHFNQPLDILIPDYPRYLAERLK 152


>UniRef50_Q4QJW2 Methylglyoxal synthase n=45 Tax=cellular organisms RepID=MGSA_HAEI8
          Length = 152

 Score =  203 bits (516), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 91/151 (60%), Positives = 123/151 (81%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M+ TTRTL   K IALVAHD CK+ L++W ++H+  L+ H+LYATGTTG+++ R TG+++
Sbjct: 1   MQTTTRTLTQHKRIALVAHDSCKKNLLNWTQKHKEALKPHILYATGTTGHILERETGLSI 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
            ++LSGPMGGDQQ+G LI+E KID++IFFWDP+NA PHDPDVKAL+R+ATVWNIPVA N 
Sbjct: 61  QSLLSGPMGGDQQLGGLIAEKKIDMMIFFWDPMNAAPHDPDVKALMRIATVWNIPVAINQ 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRL 151
           ++ADF++ S  F   V+I +PDY+ YL +RL
Sbjct: 121 SSADFLLTSVLFEQDVEIDVPDYEGYLKERL 151


>UniRef50_Q72NU6 Methylglyoxal synthase n=20 Tax=Bacteria RepID=MGSA_LEPIC
          Length = 148

 Score =  201 bits (512), Expect = 5e-51,   Method: Composition-based stats.
 Identities = 74/139 (53%), Positives = 102/139 (73%)

Query: 7   TLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSG 66
           ++PA K I L+AHD+ K+ L++WV+ H+ +L +H LY TGTTG LIS  T + V   LSG
Sbjct: 5   SVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYRFLSG 64

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GA I+EG +D++IFFWDPL A PHDPDVKALLR+A ++N+P+A N +TAD++
Sbjct: 65  PLGGDQQIGAKIAEGDLDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRSTADYM 124

Query: 127 IQSPHFNDAVDILIPDYQR 145
           I SP F      ++  Y  
Sbjct: 125 ISSPQFTKTYKKILLSYNT 143


>UniRef50_B8I1E7 Methylglyoxal synthase n=13 Tax=Firmicutes RepID=B8I1E7_CLOCE
          Length = 153

 Score =  200 bits (509), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 68/141 (48%), Positives = 98/141 (69%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
           ++   L  +KHIAL+AHD+ K+ L++WV+    +L +H L  TGTT  +I+  TG+ V  
Sbjct: 1   MSGNKLGRQKHIALIAHDNRKEDLINWVKSKSDILCRHFLCGTGTTAKMITENTGLPVKK 60

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
             SGP+GGDQQ+GA I+ G++D +IFFWD L + PHDPDVKALLR+A +++IPVA N +T
Sbjct: 61  FKSGPLGGDQQIGACIANGEVDFMIFFWDTLTSQPHDPDVKALLRIAVLYDIPVAMNRST 120

Query: 123 ADFIIQSPHFNDAVDILIPDY 143
           ADF++ S    D  +  + DY
Sbjct: 121 ADFLLTSSLMEDDYERNVVDY 141


>UniRef50_A4BFH8 Methylglyoxal synthase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BFH8_9GAMM
          Length = 147

 Score =  200 bits (508), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 72/141 (51%), Positives = 98/141 (69%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGG 70
           +++IALVAHD+ K+ L+ W      L+ +  ++ATGTTG LI  A    VN +LSGP+GG
Sbjct: 3   QRNIALVAHDNKKKELVDWAVAKAELMAEIGIFATGTTGRLIEDAMKRPVNRLLSGPLGG 62

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
           DQQ+GA I+EG+ID+LIFFWDPL   PHDPD+KALLR+A ++NIPVA N A+AD++I SP
Sbjct: 63  DQQIGAKIAEGEIDLLIFFWDPLEPQPHDPDIKALLRIAALYNIPVACNKASADYMIHSP 122

Query: 131 HFNDAVDILIPDYQRYLADRL 151
             +       PD+  Y   + 
Sbjct: 123 LLHGDYVPDEPDFSDYTLRKT 143


>UniRef50_Q2SK75 Methylglyoxal synthase n=2 Tax=Gammaproteobacteria RepID=MGSA_HAHCH
          Length = 153

 Score =  197 bits (501), Expect = 9e-50,   Method: Composition-based stats.
 Identities = 78/149 (52%), Positives = 102/149 (68%), Gaps = 1/149 (0%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M            +AL+AHD+ K  L++WVE++   L +  +YATGTTG LI+  TG++V
Sbjct: 1   MTDQVNRPKGVTSVALIAHDNKKADLIAWVEKNSVKLNKCTVYATGTTGKLIAEKTGVDV 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
               SGP+GGDQQ+GALISEGK+D+LIFFWDPL  +PHDPD+KALLRLAT+WN+P A N 
Sbjct: 61  KRCHSGPLGGDQQIGALISEGKVDLLIFFWDPLEPMPHDPDIKALLRLATLWNVPSACNS 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLAD 149
           ATADF++ S  F        PD+  YL+ 
Sbjct: 121 ATADFLVNSNLFE-EFLPQRPDFDSYLSR 148


>UniRef50_A9KFK7 Methylglyoxal synthase n=6 Tax=Coxiella burnetii RepID=MGSA_COXBN
          Length = 143

 Score =  197 bits (500), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 75/138 (54%), Positives = 97/138 (70%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           K IALVAHD  K+ L+ W+++HQ LL+ H LYATG+TG  I +   + V  M SGP+GGD
Sbjct: 4   KKIALVAHDRMKKELIEWIKKHQNLLKHHELYATGSTGQAIEKTLNVTVTKMESGPLGGD 63

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
            Q+GA I   +ID+LIFFWDPL A PHDPDV+ALLR+A VWN+PVA N +TAD+++ SP 
Sbjct: 64  LQLGAKIVNKEIDILIFFWDPLEAQPHDPDVRALLRIAVVWNLPVACNASTADYLLTSPL 123

Query: 132 FNDAVDILIPDYQRYLAD 149
           F+       PDY+ Y   
Sbjct: 124 FDSDYHPETPDYEAYRNR 141


>UniRef50_B9MRV5 Methylglyoxal synthase n=158 Tax=cellular organisms
           RepID=MGSA_ANATD
          Length = 141

 Score =  195 bits (496), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 68/141 (48%), Positives = 100/141 (70%), Gaps = 2/141 (1%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K++++ +   ++ +L +H LYATGTTG LI  ATG+ V+  L GP+GGD
Sbjct: 1   MNIALIAHDKKKELMVQFAIAYKFILSKHTLYATGTTGRLIQEATGLEVHRFLPGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+G+LI+  +ID++IF  DPL A PH+PDV ALLRL  V NIP+ATN+ATA+ +I++  
Sbjct: 61  QQIGSLIAYNQIDMVIFLRDPLTAQPHEPDVNALLRLCDVHNIPLATNIATAELLIKALD 120

Query: 132 FNDA--VDILIPDYQRYLADR 150
             D    +I+ P  Q+  +D+
Sbjct: 121 RGDLSWREIVNPKLQKNKSDK 141


>UniRef50_A0LVE0 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A0LVE0_ACIC1
          Length = 167

 Score =  193 bits (491), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 73/145 (50%), Positives = 96/145 (66%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M     T   R+HIALVAHD+ K+ L+ W   ++  L QH LYATGTTG L+     + +
Sbjct: 1   MTTQALTGTPRRHIALVAHDNKKRELLEWAAYNRATLAQHELYATGTTGALLREQLDLEI 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +LSGP+GGD Q+GA I+ G +D+L+FFWDPL   PHDPDVKALLR+A +WNI +A N 
Sbjct: 61  RCLLSGPLGGDLQIGAQIAAGSVDLLVFFWDPLEPQPHDPDVKALLRVAVLWNIAIACNR 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQR 145
            TAD +I SP F+    I  P Y++
Sbjct: 121 TTADMVISSPLFSGPYQIHRPTYRQ 145


>UniRef50_C6BZQ4 Methylglyoxal synthase n=7 Tax=Bacteria RepID=MGSA_DESAD
          Length = 157

 Score =  190 bits (483), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 77/157 (49%), Positives = 102/157 (64%), Gaps = 13/157 (8%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT----------G 57
           +   K+IA+VAHD+CK+ L+ +V+ +  +L +H L ATGTTG L+ +            G
Sbjct: 1   MSKVKNIAVVAHDNCKKELLDFVDCNHNILSRHNLVATGTTGGLVEKMIMERVEQKADEG 60

Query: 58  M---NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNI 114
                VN M SGP+GGDQQ+GA+ISEGKIDVLIFFWDP+   PHD DVKALLRLA ++NI
Sbjct: 61  YEFKPVNRMKSGPLGGDQQLGAMISEGKIDVLIFFWDPMQPQPHDVDVKALLRLAVLYNI 120

Query: 115 PVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRL 151
           P A+N +TA+F+I SP F         D+  Y   +L
Sbjct: 121 PTASNRSTAEFLISSPFFEGEFQRKETDFSSYTQRKL 157


>UniRef50_UPI0001745D5F methylglyoxal synthase n=1 Tax=Verrucomicrobium spinosum DSM 4136
           RepID=UPI0001745D5F
          Length = 154

 Score =  188 bits (479), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 72/138 (52%), Positives = 95/138 (68%), Gaps = 1/138 (0%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
            I LVAHDHCK  L++W ++H+  L+   L ATGTTG+L+ +  G+ V   LSGP+GGD 
Sbjct: 3   TIGLVAHDHCKDNLLAWAQKHREQLQGWTLCATGTTGSLLEKELGLPVRRFLSGPLGGDL 62

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           Q+G  I+EG++D+LIFFWDPL+A PHDPDVKALLR+A +WN+PVA N A AD ++     
Sbjct: 63  QIGTEIAEGRMDLLIFFWDPLSAQPHDPDVKALLRVAVLWNVPVAMNEAGADLLLIGLAQ 122

Query: 133 NDAVDILIPDYQRYLADR 150
                  IPD+  Y A R
Sbjct: 123 G-TYQRFIPDHTNYRAVR 139


>UniRef50_Q1QX97 Methylglyoxal synthase n=4 Tax=Bacteria RepID=Q1QX97_CHRSD
          Length = 159

 Score =  188 bits (478), Expect = 4e-47,   Method: Composition-based stats.
 Identities = 81/149 (54%), Positives = 106/149 (71%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              TRTLPARK IAL+AHD  K  L++W ER +  L +H L  TGTT   ++   G+ V+
Sbjct: 8   RQATRTLPARKRIALIAHDGKKAELLAWAERWRDTLARHDLVGTGTTAQRVAETLGLEVH 67

Query: 62  AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            ++SGP+GGDQQ+GA I+E ++D+L+FFWDP   +PHDPDVKALLRLA +WN+PVATN A
Sbjct: 68  GLMSGPLGGDQQIGARITESRLDMLVFFWDPFAPMPHDPDVKALLRLAALWNLPVATNAA 127

Query: 122 TADFIIQSPHFNDAVDILIPDYQRYLADR 150
           +ADFII SP     V + +PD   +LA R
Sbjct: 128 SADFIITSPLVAQEVTVNVPDANDWLATR 156


>UniRef50_B0KAD1 Methylglyoxal synthase n=27 Tax=cellular organisms RepID=MGSA_THEP3
          Length = 132

 Score =  187 bits (474), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 62/131 (47%), Positives = 93/131 (70%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K++++++   ++ + E+  +YATG TG LI  ATG+NVN +L GP+GGD
Sbjct: 1   MNIALIAHDQKKELMVNFAIAYKHIFEKCNIYATGHTGQLIKEATGLNVNCLLPGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA+I+E KID++IF  DPL A PH+PD+ ALLR+  V +IP+ATN+ATA+ +++   
Sbjct: 61  QQIGAMIAENKIDMVIFLRDPLTAQPHEPDILALLRVCDVHSIPLATNIATAEVLLKGME 120

Query: 132 FNDAVDILIPD 142
                   I D
Sbjct: 121 QGLLEWREIED 131


>UniRef50_A4IQ66 Methylglyoxal synthase n=37 Tax=Bacteria RepID=MGSA_GEOTN
          Length = 144

 Score =  183 bits (464), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 58/123 (47%), Positives = 85/123 (69%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
             IAL+AHD  K  ++++   + P+L  H LYATGTTG  I  ATG+ V+   SGP GGD
Sbjct: 1   MKIALIAHDEKKAEMVAFATAYAPVLANHELYATGTTGLRIQEATGLAVHRFQSGPYGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           Q++GA+I+  ++D++IFF DPL A PH+PD+ AL+RL  V+ +P+ATN+ TA+ +I+   
Sbjct: 61  QEIGAMIARNEMDLVIFFRDPLTAQPHEPDISALMRLCDVYAVPLATNIGTAELLIRGLE 120

Query: 132 FND 134
             D
Sbjct: 121 RGD 123


>UniRef50_C1TMX7 Methylglyoxal synthase n=1 Tax=Dethiosulfovibrio peptidovorans DSM
           11002 RepID=C1TMX7_9BACT
          Length = 157

 Score =  179 bits (454), Expect = 3e-44,   Method: Composition-based stats.
 Identities = 66/143 (46%), Positives = 96/143 (67%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
           + A K IALVAHD  K+ L+ W +RH+  L  H L +TGTTG L+  A G+ ++ + SGP
Sbjct: 1   MEAVKKIALVAHDSRKKDLIRWAKRHREQLAAHRLCSTGTTGALLEAALGLPIDKLKSGP 60

Query: 68  MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
           +GGDQQ+GA I+  ++D ++F WDPLN   HD D+KALLR+AT++NIP+A N+A+ADF+ 
Sbjct: 61  LGGDQQLGARIACERLDAIVFLWDPLNTQAHDSDIKALLRIATLYNIPMACNMASADFLF 120

Query: 128 QSPHFNDAVDILIPDYQRYLADR 150
            SP  +   +    D+  +   R
Sbjct: 121 SSPLISLPYNNEHRDFDAHQQAR 143


>UniRef50_A6L618 Methylglyoxal synthase n=34 Tax=Bacteroidales RepID=A6L618_BACV8
          Length = 178

 Score =  178 bits (451), Expect = 5e-44,   Method: Composition-based stats.
 Identities = 67/146 (45%), Positives = 84/146 (57%), Gaps = 8/146 (5%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA-------TGMNVNAML 64
           + I LVAHD  K+ ++ WV  +   L  H  Y TGTTG LI +A          ++  + 
Sbjct: 6   RRIGLVAHDAMKKDMIEWVLWNSERLIGHKFYCTGTTGTLIKKALEEKHPEIKWDITILK 65

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
           SGP+GGDQQ+G+ I EG+ID L FF DP+   PHD DVKAL RLA V NI    N +TAD
Sbjct: 66  SGPLGGDQQIGSRIVEGEIDYLFFFTDPMTLQPHDTDVKALTRLAGVENIVFCCNRSTAD 125

Query: 125 FIIQSPHFNDA-VDILIPDYQRYLAD 149
            II SP F D   + + PDY  Y   
Sbjct: 126 HIITSPLFTDPTYERIHPDYTNYTQR 151


>UniRef50_B1YKL9 Methylglyoxal synthase n=78 Tax=Bacteria RepID=MGSA_EXIS2
          Length = 144

 Score =  177 bits (449), Expect = 9e-44,   Method: Composition-based stats.
 Identities = 56/123 (45%), Positives = 84/123 (68%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K  +M +   ++    ++ LYATGTTG  I  AT + V+   SGP+GGD
Sbjct: 1   MNIALIAHDEKKDEMMMFTRAYEAYFAKNTLYATGTTGQRIMEATALTVHRCKSGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           Q++GA+++ G+ID++IF  DPL A PH+PDV AL+RL  V+++P+ATNV TA+ +I    
Sbjct: 61  QEIGAMVARGEIDIVIFLRDPLTAQPHEPDVSALIRLCDVYDLPLATNVGTAEILINGLE 120

Query: 132 FND 134
             +
Sbjct: 121 QGE 123


>UniRef50_C2HDU2 Methylglyoxal synthase n=12 Tax=Enterococcus faecium
           RepID=C2HDU2_ENTFC
          Length = 150

 Score =  175 bits (444), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 61/131 (46%), Positives = 91/131 (69%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
           LT     +   IAL+AHD  K M++     ++ +LE+H L+ATGTTG  I+ ATG+ ++ 
Sbjct: 2   LTISKGVSLMKIALIAHDRKKSMMVKLATAYKTILEKHELFATGTTGQRITEATGLPIHR 61

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
             SGP+GGDQQ+GA+ISE ++D++IF  DPL A PH+PDV AL+RL+ V+ IP+ATN+ T
Sbjct: 62  FKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYEIPLATNIGT 121

Query: 123 ADFIIQSPHFN 133
           A+ +++     
Sbjct: 122 AEVLLRGLEAG 132


>UniRef50_Q55452 Uncharacterized protein sll0036 n=7 Tax=Bacteria RepID=Y036_SYNY3
          Length = 433

 Score =  174 bits (442), Expect = 6e-43,   Method: Composition-based stats.
 Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 1/139 (0%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
           HIAL+AHD+ K  L+++V++H+ L  ++ L ATG TG L+   TG+ V+ + SGP+GGD 
Sbjct: 4   HIALIAHDNKKDALVNFVQQHKSLFSRYDLIATGQTGELVRNKTGLAVDTVFSGPLGGDT 63

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           Q+   I +G I  +IF  DPL A PH+PD++ LLRL  V+N+P+A N+ATA  +I+    
Sbjct: 64  QIATQIIDGTIAAVIFLIDPLYAQPHEPDIRTLLRLCEVYNVPLAINLATAKAVIKLLGK 123

Query: 133 ND-AVDILIPDYQRYLADR 150
                 I  P   +   +R
Sbjct: 124 TKTGHLIFNPVAGQGNVER 142


>UniRef50_D0MG34 Methylglyoxal synthase n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MG34_RHOM4
          Length = 140

 Score =  174 bits (442), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 54/121 (44%), Positives = 76/121 (62%)

Query: 9   PARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM 68
              + IAL+AHD  K  ++++  +H+ LL +  L  TGTTG L+    G+ V   LSGP+
Sbjct: 3   ETIRTIALIAHDGKKADMVAFAMQHRDLLARFELVGTGTTGKLLEEKVGLRVRRFLSGPL 62

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
           GGD Q+ A +  G I  + FF DPL+  PHDPD++ LLR   V N+P+ATN ATA +I+ 
Sbjct: 63  GGDVQIAARVVTGDIHAVFFFVDPLDKHPHDPDIQTLLRACNVHNVPLATNPATAHYILT 122

Query: 129 S 129
           S
Sbjct: 123 S 123


>UniRef50_Q3AGN5 Cyclic nucleotide-binding domain (CNMP-BD) protein n=1
           Tax=Synechococcus sp. CC9605 RepID=Q3AGN5_SYNSC
          Length = 297

 Score =  174 bits (441), Expect = 8e-43,   Method: Composition-based stats.
 Identities = 58/154 (37%), Positives = 89/154 (57%), Gaps = 3/154 (1%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV- 60
           +        RK++AL+AH++ K+ LM +   H   LE+  L ATGTTG+++ + TG+ + 
Sbjct: 139 KAAENYTDTRKYLALIAHNNMKESLMEFCGMHSRKLEKFPLMATGTTGSMLYKKTGLVLS 198

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             + SGP+GGDQ VG LIS   I  +IFF DPL+  PH  D++AL RL  V+ +P ATN 
Sbjct: 199 KKVASGPLGGDQAVGTLISTRNIIGVIFFRDPLSPHPHHADIEALGRLCDVYQVPFATNP 258

Query: 121 ATADFIIQSPHFNDAVDILIPDY--QRYLADRLK 152
            + + I+       +    IP++  Q Y+  + K
Sbjct: 259 QSGEAILDYLLSGKSERESIPNHVLQTYIQGQTK 292


>UniRef50_C9KKW1 Methylglyoxal synthase n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KKW1_9FIRM
          Length = 132

 Score =  173 bits (440), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 54/129 (41%), Positives = 82/129 (63%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           K IAL+AHD  K  ++ +V  H+  L +  L AT TTG LI+   G+ V  MLSGP+GGD
Sbjct: 2   KTIALIAHDKKKSEMLEFVGHHKDFLAKFHLIATRTTGTLINDTFGLGVETMLSGPLGGD 61

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA ++ G++D ++F  DPL + PH+PD+ ALLRL  V ++P+ATN  +A  ++    
Sbjct: 62  QQIGARVAVGEVDYVVFLRDPLTSQPHEPDINALLRLCDVHDVPLATNRKSAHILLAYAA 121

Query: 132 FNDAVDILI 140
            ++  +   
Sbjct: 122 AHEGDEPAE 130


>UniRef50_D2BG68 Methylglyoxal synthase n=5 Tax=Dehalococcoides RepID=D2BG68_DEHSV
          Length = 144

 Score =  173 bits (439), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 59/142 (41%), Positives = 91/142 (64%), Gaps = 1/142 (0%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
            R  +ALVAHD+ KQ ++  V++H+  L    L AT TTG LI  +T +NVN + SGP+G
Sbjct: 2   ERITLALVAHDNKKQEMVELVKKHETDLGSLNLVATRTTGKLIQASTSLNVNLLQSGPLG 61

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GDQQ+GA+++ G +  +IF  DPL A PH+PD+ AL+R+  V N+P+ATN++TA+ ++  
Sbjct: 62  GDQQIGAMVASGVVTAIIFLRDPLTAQPHEPDISALMRVCDVHNVPLATNISTAEAVLH- 120

Query: 130 PHFNDAVDILIPDYQRYLADRL 151
             F    ++     +  L + L
Sbjct: 121 LIFEHPEELKEHRLKSQLLNSL 142


>UniRef50_UPI0000E11027 methylglyoxal synthase n=1 Tax=Rhodobacterales bacterium HTCC2255
           RepID=UPI0000E11027
          Length = 151

 Score =  172 bits (436), Expect = 4e-42,   Method: Composition-based stats.
 Identities = 69/146 (47%), Positives = 94/146 (64%), Gaps = 2/146 (1%)

Query: 5   TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAM 63
           T+T    K IA+VAHD  K   + W + H   L  H ++ATGTTG LI  A   +++ A+
Sbjct: 2   TQTTVVTKRIAIVAHDKMKPQAIEWTKTHASKLNSHQIFATGTTGKLIQAANPNLSIKAL 61

Query: 64  LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
            SGP+GGDQQ+GA+I EG++D+L FF DP+   PHD D+KALLRL+T++N  VA N+ATA
Sbjct: 62  KSGPLGGDQQLGAMICEGQLDILFFFTDPMTPQPHDVDIKALLRLSTMYNCVVACNIATA 121

Query: 124 DFIIQSPHFNDAVDILIPDYQRYLAD 149
           DF+I+SP F         D+  Y   
Sbjct: 122 DFVIESPLFVLP-QTHTSDFSDYSER 146


>UniRef50_Q10YJ6 Cyclic nucleotide-binding protein n=2 Tax=Bacteria
           RepID=Q10YJ6_TRIEI
          Length = 322

 Score =  171 bits (433), Expect = 7e-42,   Method: Composition-based stats.
 Identities = 53/150 (35%), Positives = 91/150 (60%), Gaps = 3/150 (2%)

Query: 6   RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA-ML 64
            ++ + K++AL+AH+  K  L+ +V+ H  L+ +  L ATGTTG L+ +ATG+ ++  + 
Sbjct: 147 FSVDSTKYLALIAHNEMKSSLVEFVKEHIKLITKFPLVATGTTGLLLHQATGVVLSRKVK 206

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
           SGP+GGDQ +G++IS   I  ++FF DPL++ PH  D++AL RL  V+ +P+ATN +TA 
Sbjct: 207 SGPLGGDQAIGSMISTDNICGVLFFRDPLSSHPHHADIEALSRLCDVYQVPLATNPSTAK 266

Query: 125 FIIQSPHFN--DAVDILIPDYQRYLADRLK 152
            I+        +          +Y  ++ +
Sbjct: 267 AILLYLDNTPLEGKHNFSLALTKYQENQSR 296


>UniRef50_Q8UIV6 Methylglyoxal synthase n=8 Tax=Alphaproteobacteria RepID=MGSA_AGRT5
          Length = 127

 Score =  169 bits (429), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 61/122 (50%), Positives = 85/122 (69%), Gaps = 1/122 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAMLSG 66
           +  ++ IAL+AHD  K  +  +   HQ +L    + ATGTTG  +  A  G+ V  + SG
Sbjct: 1   MEGQRCIALIAHDEKKDDMADFARHHQKVLASFRIVATGTTGGRVQEACPGLEVIRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GA+I+ G++D+LIFF DPL A+PHD DVKAL RLATV++IP+A N ATA+ +
Sbjct: 61  PLGGDQQIGAMIATGEVDMLIFFTDPLTAMPHDVDVKALTRLATVYDIPMALNRATAENL 120

Query: 127 IQ 128
           I 
Sbjct: 121 ID 122


>UniRef50_Q2RSM7 Methylglyoxal synthase n=1 Tax=Rhodospirillum rubrum ATCC 11170
           RepID=Q2RSM7_RHORT
          Length = 155

 Score =  169 bits (429), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 65/149 (43%), Positives = 84/149 (56%), Gaps = 5/149 (3%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISR-ATGMNVNAMLSG 66
            P R  I LVAHD  K+ +  WV  +  +L  H L ATGTT  ++       ++  + SG
Sbjct: 7   TPPRMTIGLVAHDGQKRAMGQWVAANATVLGHHALVATGTTARVLKEQNPTFDITGLKSG 66

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P GGDQQ+GALI+EG +D LIFF DP+   PHD DVKAL+RLA V  IP A N ATAD +
Sbjct: 67  PFGGDQQLGALIAEGHLDCLIFFVDPMEPQPHDVDVKALIRLAQVHEIPAACNRATADLM 126

Query: 127 IQSPHFN----DAVDILIPDYQRYLADRL 151
           I SP F      +       +  Y   ++
Sbjct: 127 ITSPLFGVLRAGSFPPAEERFAVYANRKV 155


>UniRef50_C4ZA41 Methylglyoxal synthase n=10 Tax=Firmicutes RepID=C4ZA41_EUBR3
          Length = 131

 Score =  167 bits (423), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 52/123 (42%), Positives = 80/123 (65%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +I LVAHD  K+++ ++   ++ +L ++ LYATGTTG LI     ++V+  L+G +GG 
Sbjct: 1   MNIGLVAHDSKKKLMQNFCIAYRGILSKNNLYATGTTGRLIEEVANLSVHKYLAGHLGGI 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA I    ID++IF  DPL   PH+P+V ++ R+    NIP+ATN+ATA+ +I S  
Sbjct: 61  QQLGAQIEHNDIDLVIFLRDPLKPKPHEPEVNSIFRICDEHNIPLATNLATAELLILSLD 120

Query: 132 FND 134
             D
Sbjct: 121 RGD 123


>UniRef50_Q72HP3 Methylglyoxal synthase n=3 Tax=Bacteria RepID=MGSA_THET2
          Length = 126

 Score =  166 bits (422), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 55/116 (47%), Positives = 83/116 (71%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           K +AL+AHD  K  ++++  RH+ +L ++ L ATGTTG  I  ATG+ V  +LSGP+GGD
Sbjct: 2   KALALIAHDAKKDEMVAFCLRHKDVLARYPLLATGTTGARIQEATGLAVERVLSGPLGGD 61

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
            Q+GA ++EGK+  ++F  DPL A PH+PDV+AL+R+  V  +P+ATN+  A+ +I
Sbjct: 62  LQIGARVAEGKVLAVVFLQDPLTAKPHEPDVQALMRVCNVHGVPLATNLVAAEALI 117


>UniRef50_C3MBY3 Methylglyoxal synthase n=5 Tax=Alphaproteobacteria RepID=MGSA_RHISN
          Length = 126

 Score =  164 bits (415), Expect = 1e-39,   Method: Composition-based stats.
 Identities = 62/122 (50%), Positives = 85/122 (69%), Gaps = 1/122 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAMLSG 66
           +  RK +AL+AHD  K  L ++ + H+  L    + ATGTTG  +  A  G++V  + SG
Sbjct: 1   MADRKCLALIAHDQKKNDLAAFAKAHEATLSGWKIVATGTTGGRVLDACPGLDVTRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GALI+ G +D LIFF DPL A+PHD DVKAL+RLA V++IP+A N ATA+ +
Sbjct: 61  PLGGDQQIGALIATGDVDCLIFFVDPLTAMPHDVDVKALMRLAIVYDIPMALNRATAEQL 120

Query: 127 IQ 128
           I 
Sbjct: 121 ID 122


>UniRef50_A3MI51 Methylglyoxal synthase n=96 Tax=Bacteria RepID=MGSA_BURM7
          Length = 130

 Score =  161 bits (409), Expect = 5e-39,   Method: Composition-based stats.
 Identities = 55/124 (44%), Positives = 82/124 (66%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
           +   IAL+AHD  K  +++    ++  L Q  L ATGTTG  I++A G++V   LSGP+G
Sbjct: 2   STPRIALIAHDAKKDDIVALAGAYRATLAQCRLVATGTTGGRIAQAHGLDVERKLSGPLG 61

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GD Q+GA +++G++D++IF  DP+ A PHDPD+ AL+R   V ++PVATNVATA  ++  
Sbjct: 62  GDLQIGAELADGRVDIVIFLRDPMTAQPHDPDITALVRACDVHDVPVATNVATARVLLDD 121

Query: 130 PHFN 133
               
Sbjct: 122 LARR 125


>UniRef50_P58761 Methylglyoxal synthase n=6 Tax=Bacteria RepID=MGSA_TRESO
          Length = 158

 Score =  160 bits (406), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 54/141 (38%), Positives = 79/141 (56%), Gaps = 6/141 (4%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA-----TGMNVNAMLSGP 67
            IALVAHD+ K  ++ W   +  +L QH L+ TGTTG L+  +        ++  M SGP
Sbjct: 6   RIALVAHDNRKADIVDWALNNAEMLSQHRLFGTGTTGTLVRESFMKRGIASDITCMHSGP 65

Query: 68  MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
           MGGD ++ AL+   +ID  +FF D LN  PH+ D++ LLR   + NIP+A N  +AD +I
Sbjct: 66  MGGDAEIAALVVRKEIDFAVFFIDDLNPQPHEADIQMLLRQCRIHNIPIACNRYSADLMI 125

Query: 128 QSPHFND-AVDILIPDYQRYL 147
            S  ++D       P Y  + 
Sbjct: 126 TSSLWDDAGYVPKDPIYAPFD 146


>UniRef50_B3PXK7 Methylglyoxal synthase n=23 Tax=Bacteria RepID=MGSA_RHIE6
          Length = 126

 Score =  160 bits (405), Expect = 1e-38,   Method: Composition-based stats.
 Identities = 58/125 (46%), Positives = 85/125 (68%), Gaps = 1/125 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTG-NLISRATGMNVNAMLSG 66
           +   K +AL+AHD  K  + ++   ++ LL +  + ATGTTG  ++  A  ++V  + SG
Sbjct: 1   MAGGKCLALIAHDQKKDDMAAFARANRDLLSRWKIVATGTTGGRVLDAAPDLDVTRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GALIS G++D LIFF DPL  +PHD DVKAL+RLA V++IP+A N ATA  +
Sbjct: 61  PLGGDQQIGALISTGEVDALIFFVDPLTPMPHDVDVKALMRLAIVYDIPMALNHATAIKL 120

Query: 127 IQSPH 131
           + +  
Sbjct: 121 LPTLE 125


>UniRef50_A5FPH5 Methylglyoxal synthase n=5 Tax=Dehalococcoides RepID=A5FPH5_DEHSB
          Length = 143

 Score =  158 bits (400), Expect = 6e-38,   Method: Composition-based stats.
 Identities = 49/133 (36%), Positives = 75/133 (56%)

Query: 9   PARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM 68
             +  + L+AHD+CK+ ++  +  +  L++ H L AT +TG LI + TG+ V    SGP 
Sbjct: 3   EPKITLGLIAHDNCKKDMVQLIHSYAHLMKGHHLIATRSTGELIQKHTGLPVILKESGPD 62

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
           GG+ Q+G  ++   I  +IF  DPL    H+PDV AL+R+    NIP+ATN ATA  ++ 
Sbjct: 63  GGELQLGGFVASRIIKAVIFLRDPLKRKSHEPDVTALMRICDAHNIPLATNRATAACVLH 122

Query: 129 SPHFNDAVDILIP 141
              F+       P
Sbjct: 123 MALFHPEKLDDTP 135


>UniRef50_A7HN41 Methylglyoxal synthase n=1 Tax=Fervidobacterium nodosum Rt17-B1
           RepID=A7HN41_FERNB
          Length = 119

 Score =  157 bits (397), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 48/99 (48%), Positives = 69/99 (69%)

Query: 29  WVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIF 88
           +V+  + + E+  LYAT +TG +I    G+ VN   SGP GGD Q+G++I  G+ID +IF
Sbjct: 2   FVKEWKNVFERCELYATKSTGKIIEEKIGLKVNKFESGPYGGDLQIGSMIVNGEIDFVIF 61

Query: 89  FWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
             DPL A PH+PDV ALLR+  V N+P+ATN+ATA+ ++
Sbjct: 62  LRDPLTAQPHEPDVSALLRVCDVHNVPLATNLATAEALV 100


>UniRef50_C9L646 Methylglyoxal synthase n=12 Tax=Bacteria RepID=C9L646_RUMHA
          Length = 130

 Score =  156 bits (394), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 45/130 (34%), Positives = 73/130 (56%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            ++ ++AH+  K ++  +   ++ +L +H +YATGTTG  I   T + V+  L G MGGD
Sbjct: 1   MNVGIIAHNSKKALIEDFCIAYKNILAKHEIYATGTTGRRIEEVTNLRVHKFLPGSMGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           +Q   +I  G ID++IFF++P      +PDV  +      +NIP+ATN+ATA+ +I    
Sbjct: 61  KQFTEMIERGDIDMVIFFYNPAMIDGTEPDVYQISGCCDQYNIPIATNIATAESLILGLE 120

Query: 132 FNDAVDILIP 141
             D    L  
Sbjct: 121 QGDLDYRLNR 130


>UniRef50_A4J7I4 Methylglyoxal synthase n=1 Tax=Desulfotomaculum reducens MI-1
           RepID=A4J7I4_DESRM
          Length = 139

 Score =  156 bits (394), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 48/114 (42%), Positives = 73/114 (64%)

Query: 17  VAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGA 76
           +A  + K    +  +  Q  L QH L  TGTTG+LI    G++V   +SGP+GGDQQ+G 
Sbjct: 24  LAFSYVKNSENALDKEFQLQLSQHDLIGTGTTGSLIKEKVGLDVTCYMSGPLGGDQQIGG 83

Query: 77  LISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
            I++G++ ++IF  DPL   PH+PD+ AL R+  V NIP+ATN++TA  ++ + 
Sbjct: 84  KIAQGEVGLVIFLRDPLTPQPHEPDINALSRICNVHNIPIATNISTAKVLLNNL 137


>UniRef50_C1MXR9 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MXR9_9CHLO
          Length = 281

 Score =  155 bits (392), Expect = 4e-37,   Method: Composition-based stats.
 Identities = 50/141 (35%), Positives = 79/141 (56%), Gaps = 2/141 (1%)

Query: 5   TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV-NAM 63
            +     K +ALVAH+H K  L+ +V  +        +  TG+TG+++    G+ + + +
Sbjct: 117 AKKTTETKLVALVAHNHMKAPLLHFVASNMDFFSTVSIVTTGSTGSVLESNLGLTITHKV 176

Query: 64  LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
            SGP+GGDQ++G + S  ++    FF DPL+A PHD D+KAL R+  V N+PVATN AT 
Sbjct: 177 SSGPLGGDQEIGGMASLNQVGGAFFFIDPLSAHPHDDDIKALCRICNVHNVPVATNPATG 236

Query: 124 DFIIQSPHFNDAVDILIPDYQ 144
             ++ +   ND       D +
Sbjct: 237 KGLVYAFL-NDEYMKSTLDLK 256


>UniRef50_B0C5A3 Putative uncharacterized protein n=1 Tax=Acaryochloris marina
           MBIC11017 RepID=B0C5A3_ACAM1
          Length = 430

 Score =  150 bits (378), Expect = 2e-35,   Method: Composition-based stats.
 Identities = 49/141 (34%), Positives = 77/141 (54%), Gaps = 1/141 (0%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGG 70
              IAL+AH+  K  +++ V+R+  LL ++++ AT  TG  I  AT + V  ++S   GG
Sbjct: 2   PNSIALIAHESKKNDIVTLVQRYHSLLNRYLIVATPDTGKWIQDATNLTVETVVSEADGG 61

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
             Q+ A +   ++  +IF  D +N     PDV+ALLR+   + +P+ATN+ATA+  IQ  
Sbjct: 62  LLQIAARLVSSEVVGVIFLMDTINVPSQLPDVQALLRVCNRYEVPLATNIATAELAIQGV 121

Query: 131 -HFNDAVDILIPDYQRYLADR 150
               DA  I  P   +   DR
Sbjct: 122 AKRRDAYLIFNPIAGQGNPDR 142


>UniRef50_A5FB35 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A5FB35_FLAJ1
          Length = 133

 Score =  146 bits (368), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 47/123 (38%), Positives = 75/123 (60%), Gaps = 3/123 (2%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLL--EQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
             IA++AHD  K  L+ ++ +++ +L  E+  L  TGTTG   + A G     MLSGP+G
Sbjct: 10  MEIAIIAHDGKKADLIDFLIKNEAVLHNEKIRLIGTGTTGGK-AEAAGFKTQRMLSGPLG 68

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GD Q+   ++EG   ++ FF DPL++ PH+ D+  L+R+  V N+P+ATN ATA  ++ +
Sbjct: 69  GDAQIAGRVAEGITQMVFFFKDPLSSHPHEADINMLIRVCDVHNVPLATNEATAQLLLDA 128

Query: 130 PHF 132
              
Sbjct: 129 IAQ 131


>UniRef50_Q0FI67 Methylglyoxal synthase n=3 Tax=Rhodobacteraceae RepID=Q0FI67_9RHOB
          Length = 358

 Score =  140 bits (354), Expect = 1e-32,   Method: Composition-based stats.
 Identities = 50/127 (39%), Positives = 72/127 (56%), Gaps = 1/127 (0%)

Query: 6   RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAML 64
               A + IAL AHD  K  L +WV RH   LE H L  TG TG +I+ A   +++  + 
Sbjct: 227 MRSTAPRRIALAAHDTRKAHLRAWVSRHAAALEGHRLVCTGGTGQMIAEAAPQLSLRRLQ 286

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
            G  GGDQQ+GA+I+ G++D +IFF DP      + D++AL RLA + + P+A   + AD
Sbjct: 287 RGSRGGDQQLGAMIATGELDAVIFFADPTVPHGGEADLRALTRLAVLHDTPLALGPSGAD 346

Query: 125 FIIQSPH 131
            I  +  
Sbjct: 347 MIATALL 353


>UniRef50_B4SH52 Methylglyoxal synthase-like protein n=2 Tax=cellular organisms
           RepID=B4SH52_PELPB
          Length = 328

 Score =  136 bits (344), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 42/137 (30%), Positives = 64/137 (46%), Gaps = 6/137 (4%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHV-LYATGTTGNLISRATGMNV----NAML 64
               IAL+AHD  K  ++ +   H+  L Q   + ATGTTG  ++ AT   +        
Sbjct: 190 EEMTIALIAHDDMKPRMVEFAVDHEYELGQFCAILATGTTGREVAAATNRTIGNKMIRYH 249

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWN-IPVATNVATA 123
           SGP GGD ++   I  G  DV+IFF DPL+  PH  D++ +++   V + + + TN   A
Sbjct: 250 SGPKGGDIEIATAILYGHCDVVIFFVDPLSPHPHIDDIRVVVQACMVSDRVVMITNEMHA 309

Query: 124 DFIIQSPHFNDAVDILI 140
              +           L 
Sbjct: 310 REFMTRAVRGKQQLKLY 326


>UniRef50_B7S3K0 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7S3K0_PHATR
          Length = 314

 Score =  133 bits (335), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 38/147 (25%), Positives = 72/147 (48%), Gaps = 8/147 (5%)

Query: 5   TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM- 63
                  + +ALV+H+  K  +  +V  ++ +L++  L  T +T  ++S     + + + 
Sbjct: 142 AFAPSEMRCLALVSHNRMKAAMKEFVTINKNILKKFCLTGTQSTMKMLSEVFKGDSSVVF 201

Query: 64  ----LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATN 119
                SGP+GGD ++ AL+  G++  ++FF DPL+A  H  D+  L R A V N  +   
Sbjct: 202 GPSCTSGPLGGDAELAALLCRGRLGGILFFEDPLSAHAHQADIHCLCRQAQVHNTMICAT 261

Query: 120 VATADFI---IQSPHFNDAVDILIPDY 143
             +A  +   ++S    +    LIP +
Sbjct: 262 TTSALMMMHVLRSALQGNGRPELIPSF 288


>UniRef50_B5VUE7 Diacylglycerol kinase catalytic region n=2 Tax=Arthrospira
           RepID=B5VUE7_SPIMA
          Length = 444

 Score =  133 bits (334), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 3/140 (2%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
            IAL+AHD  ++ L+S+VE +   L  + L A   T   + + TG+ V  + S   GGD 
Sbjct: 4   TIALIAHDSQREELVSFVEENTVALSFYELIAPERTAQYLLQGTGVEVQVLSSLHHGGDI 63

Query: 73  QVGALIS-EGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           ++   I  E +I  +IFF DP   +   P+++ L+R   + N+P+ATN ATA  ++    
Sbjct: 64  ELAYRILQETEIAAVIFFLDPGFNLS-SPEIQVLIRACNLQNVPLATNRATARAMLSGLT 122

Query: 132 FNDAV-DILIPDYQRYLADR 150
            + +   I  P      + +
Sbjct: 123 RSRSACLIFNPVSGTGNSQQ 142


>UniRef50_B2IW98 Forkhead-associated protein n=1 Tax=Nostoc punctiforme PCC 73102
           RepID=B2IW98_NOSP7
          Length = 664

 Score =  129 bits (325), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 36/122 (29%), Positives = 63/122 (51%), Gaps = 1/122 (0%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM-G 69
            ++I L+AH+  K  L  +V +HQ    Q       + G ++ +  G+ ++     P+ G
Sbjct: 541 ERNIVLIAHESKKSELAEFVSQHQEFFSQSFTITWPSVGEVLHQQAGITISQQTPAPISG 600

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           G Q + +L+  G+I  +IF  D L   P   + +ALLRL T+  + +ATN+ TA+ I+  
Sbjct: 601 GYQTIASLVGAGEILAVIFLRDLLQPQPGQANEEALLRLCTINQVLLATNLPTAEAIVHY 660

Query: 130 PH 131
             
Sbjct: 661 LK 662


>UniRef50_D0J1U7 Methylglyoxal synthase n=3 Tax=Comamonadaceae RepID=D0J1U7_COMTE
          Length = 291

 Score =  121 bits (304), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 11/127 (8%)

Query: 9   PARKHIALVAHDHCKQMLMSWVERHQPLLEQHVL-YATGTTGNLISRAT---GMN----- 59
              + +AL+AHD  K  ++ +   +  LL ++     TGTTG  ++      G       
Sbjct: 154 YENQTLALIAHDAMKPTMLDFAAHNFELLSRYRRRVGTGTTGQKLNEMAWSKGWPADKPW 213

Query: 60  VNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRL--ATVWNIPVA 117
           V+   SGP+GGD Q+  L+ E +    IFF DP  A  H+ D++ L R       +   +
Sbjct: 214 VDRYNSGPLGGDAQIADLVLEKRCHRAIFFEDPHVARQHEADIQLLERAVTTVTHDAVCS 273

Query: 118 TNVATAD 124
           T+   A 
Sbjct: 274 TSPQVAQ 280



 Score = 39.5 bits (91), Expect = 0.034,   Method: Composition-based stats.
 Identities = 24/112 (21%), Positives = 41/112 (36%), Gaps = 9/112 (8%)

Query: 47  TTGNLISRATGMNVNAMLSGPMGGDQQVGALIS-----EGKIDVLIFFWDPLNAVPHDPD 101
           T  +++    G+       G  GG  ++ A +      E  +D  I+  DP++     P+
Sbjct: 50  TAASMLQGYKGLV--RYPYGREGGLMRLVAEVVGMEGDERTLDGAIYLMDPVDPSSIFPE 107

Query: 102 VKALLRLATVWNIPVATNVATADFIIQS--PHFNDAVDILIPDYQRYLADRL 151
             AL R   +   P  + VA+    I+    H   A D     +  Y    L
Sbjct: 108 ALALKRQCVIHGKPFLSTVASTRDWIEMERIHAGLARDRNADRFHDYENQTL 159


>UniRef50_A0YM60 Putative uncharacterized protein n=1 Tax=Lyngbya sp. PCC 8106
           RepID=A0YM60_9CYAN
          Length = 265

 Score =  121 bits (303), Expect = 8e-27,   Method: Composition-based stats.
 Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 2/121 (1%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM-- 68
           RK++ L+A +     L+ WV++   +L    ++A       + +   +NV  +++  +  
Sbjct: 143 RKYMILMADETKMSDLLDWVQKEIDILYNIPIFAPEWVAQSLQQNINLNVKQVINSNVLV 202

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
           GG   +GA I  G I  ++ F DPL   P+   + A+LRL     +  ATN+ TA  I+ 
Sbjct: 203 GGSDTIGAQIILGNIKAVVCFRDPLARRPNRASIDAILRLCDASQVICATNIQTARAILT 262

Query: 129 S 129
           +
Sbjct: 263 A 263


>UniRef50_A3YU56 Methylglyoxal synthase n=2 Tax=Synechococcus RepID=A3YU56_9SYNE
          Length = 434

 Score =  120 bits (301), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 4/141 (2%)

Query: 14  IALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISR---ATGMNVNAMLSGPMGG 70
           IAL+A     + L+ W+E+HQ LLE   L A       ++    ++G+ V+ + +   GG
Sbjct: 5   IALLASAGSNERLLGWLEQHQVLLEGFPLLAPAELVLALAEDQRSSGLKVSPLATLAAGG 64

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
           D Q+   +  G +  ++FF DP   +   PD++ LLR   +  IP+A N ATA   ++  
Sbjct: 65  DIQIAERVLAGAVGAVLFFVDPATTLATTPDLRLLLRTCALAGIPLALNEATATLALRGL 124

Query: 131 HFND-AVDILIPDYQRYLADR 150
             +  A  I  P   +   ++
Sbjct: 125 GRSRLAYLIFNPVAGQGEPNQ 145


>UniRef50_Q05TV7 Methylglyoxal synthase n=1 Tax=Synechococcus sp. RS9916
           RepID=Q05TV7_9SYNE
          Length = 435

 Score =  118 bits (295), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 34/144 (23%), Positives = 57/144 (39%), Gaps = 4/144 (2%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT---GMNVNAMLSGP 67
              + L A       L +W+  +  LL    L         + R     G+++    +  
Sbjct: 2   PSTLVLNADPVVCPALGTWMTNNTQLLSGFSLLIGEDVIEELKRRHDLGGLSITPCRAIR 61

Query: 68  MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
            GGD  + A I EG+I  L+ F  P +    D   + L+R A + + P+A N ATA  ++
Sbjct: 62  EGGDIAIAARILEGEISGLVHFPAPADQQGRDVLAEPLVRAALLCDRPIALNPATASALL 121

Query: 128 QSPHFN-DAVDILIPDYQRYLADR 150
           Q    +     I  P   +   D+
Sbjct: 122 QGVKRSRRGYLIFNPVAGQGDPDQ 145


>UniRef50_B2A170 Carbamoyl-phosphate synthase large chain n=3 Tax=Bacteria
            RepID=CARB_NATTJ
          Length = 1106

 Score =  112 bits (280), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 32/152 (21%), Positives = 60/152 (39%), Gaps = 11/152 (7%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  +  ++     + +   D  K+ +   VER Q L     ++AT  T   +    G++V
Sbjct: 960  MLASGFSINLNGGVLVTVADRDKEAVRPLVERFQKL--GLKIFATSGTAEFLRNQ-GIDV 1016

Query: 61   NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP--DVKALLRLATVWNIPVAT 118
              +    +     +  LI EG+I+ +I   +       +P  D   + R A    IP  T
Sbjct: 1017 EQVPKI-VDESPNIIDLIREGQINYVI---NTFTI-GKEPARDGFKIRRAAVENGIPCLT 1071

Query: 119  NVATADFIIQSPHFND-AVDILIPDYQRYLAD 149
            ++ TA  ++ +    D      +   Q YL +
Sbjct: 1072 SLDTASALLTAMESLDRGESKQVKSLQDYLKE 1103


>UniRef50_C9KKE3 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Mitsuokella
            multacida DSM 20544 RepID=C9KKE3_9FIRM
          Length = 1065

 Score =  111 bits (277), Expect = 8e-24,   Method: Composition-based stats.
 Identities = 24/138 (17%), Positives = 50/138 (36%), Gaps = 8/138 (5%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            +   +P +  I     D  K+ +    +    L     + AT  T   I ++ G++   +
Sbjct: 920  SGIHVPTKGCILFTVADKDKEEMKQLAKAFSEL--GFEICATEGTAKAI-QSMGIDAEVV 976

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP-DVKALLRLATVWNIPVATNVAT 122
                      +  +I  GKI+++I   + L    H   D   + R      I   T++ T
Sbjct: 977  GKVHERSSD-IIQMIKNGKINMVI---NTLTQGKHSAKDGFKIRRATVEHGIACLTSLDT 1032

Query: 123  ADFIIQSPHFNDAVDILI 140
            A  +++   F     ++ 
Sbjct: 1033 AWEVLRVLSFMRERRLVY 1050


>UniRef50_UPI0001B41F6C carbamoyl phosphate synthase large subunit n=2 Tax=Listeria
           monocytogenes RepID=UPI0001B41F6C
          Length = 224

 Score =  108 bits (271), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 24/133 (18%), Positives = 56/133 (42%), Gaps = 10/133 (7%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
            +  T+     + L   D  K+  +   +R   +     + AT  T + +  A+ + V+ 
Sbjct: 81  ASGTTMHDYGTVLLTVADRDKEEAVELAKRFNRI--GFTIMATKGTASTLEEAS-IPVSQ 137

Query: 63  MLSGPMGGDQQ-VGALISEGKIDVLIFFWDPLNA-VPHDPDVKALLRLATVWNIPVATNV 120
           +    +G +Q+ +   I  G++ +++   + L      + D   + R +    IPV T++
Sbjct: 138 VKK--IGENQETLIDYIRNGQVTLVV---NTLTTGKRPERDGFQIRRESVENGIPVCTSL 192

Query: 121 ATADFIIQSPHFN 133
            TA+ I++     
Sbjct: 193 DTAEAILRVLESR 205


>UniRef50_O67233 Carbamoyl-phosphate synthase large chain, C-terminal section n=28
           Tax=Bacteria RepID=CARB2_AQUAE
          Length = 537

 Score =  106 bits (265), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 23/130 (17%), Positives = 49/130 (37%), Gaps = 7/130 (5%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                 LP + ++ +   D  K  ++   +  + L     +YAT  T   +    G+N  
Sbjct: 392 LSAGYRLPEKGNLFISVADRDKPKILELAKEFEKL--GFGIYATSGTYKFLKEH-GVNAK 448

Query: 62  AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            +L    G    V  +I  G+I ++I   +  +      D   + R    +N+P  T + 
Sbjct: 449 RVLKVSEG-RPNVVDMIINGEIHLVI---NTPSGKREKSDAYYIRRACVQFNVPYYTTMR 504

Query: 122 TADFIIQSPH 131
               ++++  
Sbjct: 505 AGYAVLEAIK 514


>UniRef50_D1CBW2 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Thermobaculum
            terrenum ATCC BAA-798 RepID=D1CBW2_THET1
          Length = 1095

 Score =  105 bits (263), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 25/142 (17%), Positives = 48/142 (33%), Gaps = 9/142 (6%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M       P    + +   DH K   +        +   + L  T  T        G+ V
Sbjct: 947  MIAAGINPPPGGSVLMSIADHEKPEALPLAAALVDM--GYALVCTEGTSTFFEDN-GIRV 1003

Query: 61   NAM--LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVAT 118
            N +    G +  D  +  +I   ++ ++I    P  +     D   + R A    IP  T
Sbjct: 1004 NQVVHKIGSVRPD--ITDIIRRRQVSLVI--NTPSRSGRTIRDGFEIRRAAAESGIPCLT 1059

Query: 119  NVATADFIIQSPHFNDAVDILI 140
            ++ TA  ++++       +I  
Sbjct: 1060 SLDTAKSLVKALQRRGDYNIAT 1081


>UniRef50_B1YIR9 Carbamoyl-phosphate synthase large chain n=54 Tax=cellular organisms
            RepID=CARB_EXIS2
          Length = 1070

 Score =  105 bits (263), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 25/133 (18%), Positives = 56/133 (42%), Gaps = 10/133 (7%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  +   +P    + L   D  KQ ++   +R   L     L AT  T +++    G+ V
Sbjct: 925  LIASGMAIPEHGRVLLTVADQDKQEMLDLAKRFTAL--GFTLLATAGTASVLEEH-GLRV 981

Query: 61   NAMLSGPMGGDQ-QVGALISEGKIDVLIFFWDPLNAVPH-DPDVKALLRLATVWNIPVAT 118
              +  G +G +Q  +   I + +++ +I   + ++       D   + R A   N+   T
Sbjct: 982  QVV--GKLGSEQGSMLEWIEKAEVEYVI---NTMSRDSQVTKDGFIIRRAAAENNVVCLT 1036

Query: 119  NVATADFIIQSPH 131
            ++ TA+ +++   
Sbjct: 1037 SLDTAEALLRVIE 1049


>UniRef50_A6SWW2 Uncharacterized conserved protein n=12 Tax=cellular organisms
           RepID=A6SWW2_JANMA
          Length = 315

 Score =  104 bits (261), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 42/107 (39%), Positives = 58/107 (54%), Gaps = 11/107 (10%)

Query: 14  IALVAHDHCKQMLMSWVERHQPLLEQHVL-YATGTTGNLIS--------RATGMN-VNAM 63
           IA++AHD  K  ++   ERH  LL+Q     ATGTTG+L++           G N V   
Sbjct: 177 IAMIAHDAMKGRMLEIAERHFDLLDQFGFRCATGTTGSLLNKLAQKIKGEEAGRNWVKPY 236

Query: 64  LSGPMGGDQQVGALISEG-KIDVLIFFWDPLNAVPHDPDVKALLRLA 109
           LSGPMGGD Q+  LI +  +   ++F  DP  A  H+ D++ L R A
Sbjct: 237 LSGPMGGDAQIAELILDKDQCRRVLFLEDPHVARQHEADIQLLERAA 283



 Score = 43.0 bits (100), Expect = 0.003,   Method: Composition-based stats.
 Identities = 13/73 (17%), Positives = 32/73 (43%), Gaps = 4/73 (5%)

Query: 60  VNAMLSGPMGGDQQVGALISE----GKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIP 115
           +     G  GG  ++ + + +     ++D +++  DP++     P+  AL R   +   P
Sbjct: 80  IERFPYGRHGGLMKLVSRVVDTDPARRLDAVMYLMDPVDPSSIFPEAVALKRQCVIHGKP 139

Query: 116 VATNVATADFIIQ 128
             + +A A   ++
Sbjct: 140 FLSTLAGAREWLE 152


>UniRef50_Q9HK17 Carbamoyl-phosphate synthase large chain n=4 Tax=Thermoplasmatales
            RepID=CARB_THEAC
          Length = 1047

 Score =  103 bits (256), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 27/164 (16%), Positives = 56/164 (34%), Gaps = 25/164 (15%)

Query: 1    MELTTRTLPARKHIA---------------LVAHDHCKQMLMSWVERHQPLLEQHVLYAT 45
            M+ T   +   + +A               +   D  K  ++        L +   LYAT
Sbjct: 891  MKSTGEAMYPGRTLAEALRKSLQRSISSVLITVRDEDKPRIVDIAR--ILLEKGVKLYAT 948

Query: 46   GTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP-DVKA 104
              T   ++   G+    +       + ++  +IS G ID++I   +          D   
Sbjct: 949  AGTSKFLADH-GIPTETLYRVRDRREPRILDMISSGSIDMVI---NTTEMTAGAVRDGFK 1004

Query: 105  LLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLA 148
            + R+  +  IP+  N+  A    ++      V++   +   YL 
Sbjct: 1005 IRRICIMRGIPLIMNINLARAYAEAL---GQVEVDYREIGDYLQ 1045


>UniRef50_A5FYW1 Methylglyoxal synthase-like protein n=4 Tax=Proteobacteria
           RepID=A5FYW1_ACICJ
          Length = 318

 Score =  102 bits (255), Expect = 3e-21,   Method: Composition-based stats.
 Identities = 42/138 (30%), Positives = 57/138 (41%), Gaps = 22/138 (15%)

Query: 9   PARKHIALVAHDHCKQMLMSWVERHQPLLEQH-VLYATGTTGNLIS-------------- 53
            A + I L+AHD  K +++ +  RH  LL +     ATGTTG L++              
Sbjct: 169 TATETIGLIAHDTQKPVMLDFARRHHALLSRFGRRLATGTTGGLLNGTVPARLRAETATL 228

Query: 54  ------RATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLR 107
                    G    A  SGP GGD Q+   + EG+   LIFF DP  A  H+ D++ L R
Sbjct: 229 LPLLPPAVPGWT-TAFQSGPRGGDAQIAEEVLEGRCRRLIFFEDPHVAREHEADIQLLER 287

Query: 108 LATVWNIPVATNVATADF 125
                         TA  
Sbjct: 288 ATRFAPDGCLCINDTASA 305



 Score = 54.5 bits (130), Expect = 9e-07,   Method: Composition-based stats.
 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 14/137 (10%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQM----LMSWVERHQPLLEQ--HVLYATGTTGNLISR 54
           M+        R  I + A    +      L   +    P L      L+A G T + I  
Sbjct: 1   MDGAAAGEGGRLRIGIAASAAMRSSEVSPLFGLLRDFAPFLSSPAVALHAVGATCDAILA 60

Query: 55  A---TGMNVNAMLSGPMGGDQQVGALI---SEGK--IDVLIFFWDPLNAVPHDPDVKALL 106
           +    G     +     GG   + +++   +EG+  +D +I+  DP++ +   P+++AL 
Sbjct: 61  SGLLAGNPPARLRPAREGGVITLTSMVVPDAEGRAALDFVIYLIDPVDPIGVFPEMQALK 120

Query: 107 RLATVWNIPVATNVATA 123
           R   V   P  TN   A
Sbjct: 121 RQCVVHGRPFLTNRGAA 137


>UniRef50_C9LZI0 Carbamoyl-phosphate synthase large subunit chain n=1
           Tax=Lactobacillus helveticus DSM 20075
           RepID=C9LZI0_LACHE
          Length = 202

 Score = 99.6 bits (247), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 30/136 (22%), Positives = 61/136 (44%), Gaps = 19/136 (13%)

Query: 4   TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
               LP   ++ L   D  K+ ++   +R   +   + ++AT  T N + +   ++V  +
Sbjct: 68  AKMQLPENGNVLLTIEDRDKEKILPIAKRFARI--GYRIFATKGTANFLKKN-DLHVELV 124

Query: 64  LSGPMGGDQQ----VGALISEGKIDVLIFFWDPLNAVPHD----PDVKALLRLATVWNIP 115
                  D+Q    +   + +GKID++I      N + HD     D   + ++A   N+P
Sbjct: 125 TKVHE--DEQAYDNILNELRDGKIDLVI------NTMGHDIEKNSDGFIIRQMAIQQNVP 176

Query: 116 VATNVATADFIIQSPH 131
           + T + TAD +++S  
Sbjct: 177 LLTALDTADALLKSLE 192


>UniRef50_A2BWE6 Carbamoyl-phosphate synthase, large subunit n=56 Tax=cellular
            organisms RepID=A2BWE6_PROM5
          Length = 1100

 Score = 99.6 bits (247), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 32/144 (22%), Positives = 50/144 (34%), Gaps = 7/144 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              +   +P+     L  +D  K  L         L     L AT  T + +    G+ V+
Sbjct: 960  LASGNGVPSEGVAFLSTNDLDKDKLEEIARELIVL--GFKLIATKGTASYLL-NLGIEVD 1016

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +L    G    +  LI  G I ++I    P+ +     D   L R A  +NIP  T + 
Sbjct: 1017 EVLKVHEG-RPNIEDLIRSGLIQLVI--NTPIGSQAFHDDAY-LRRAALEYNIPTFTTIP 1072

Query: 122  TADFIIQSPHFNDAVDILIPDYQR 145
             A   +Q+        I     Q 
Sbjct: 1073 GAKAALQAIKSLRINKIDTLSLQE 1096


>UniRef50_B9KXM5 Carbamoyl-phosphate synthase large chain n=794 Tax=cellular organisms
            RepID=CARB_THERP
          Length = 1078

 Score = 98.4 bits (244), Expect = 6e-20,   Method: Composition-based stats.
 Identities = 30/129 (23%), Positives = 48/129 (37%), Gaps = 7/129 (5%)

Query: 14   IALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG-GDQ 72
            + L   D+ K   +        L   H L AT  T   + RA G+ V  +    +G G  
Sbjct: 944  VLLSLADNDKSAGVELARGLLAL--GHPLVATEGTARYL-RAHGVPVE-LTVAHIGHGHP 999

Query: 73   QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
             V  +I E K+  +I    P        D   + R A    IP  T++ TA  ++++   
Sbjct: 1000 DVLEVILERKVRGVI--NTPGRDEGTIQDGFLIRRAAVERGIPCLTSLDTARALVRALLG 1057

Query: 133  NDAVDILIP 141
                  + P
Sbjct: 1058 GGTSFSVQP 1066


>UniRef50_C6Q1M4 MGS domain protein n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6Q1M4_9CLOT
          Length = 159

 Score = 97.7 bits (242), Expect = 1e-19,   Method: Composition-based stats.
 Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 11/138 (7%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
            +   +     I +   D  K+  +  ++ +Q L      YA+  TGN +    G  ++ 
Sbjct: 24  ASGVNIVTEGSIYVSLKDVDKKEGIDIIKDYQKL--GFKFYASEGTGNYLK---GNAIDC 78

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
            +   + GD QV   I +GKI +LI    P      + +   L R A  + +PV T + T
Sbjct: 79  TI---IDGD-QVSEFIVDGKIKMLI--NTPTRGNNPESEGFKLRRKAAEYRVPVFTCIDT 132

Query: 123 ADFIIQSPHFNDAVDILI 140
           A   + + +F  + + + 
Sbjct: 133 AKIFLTAINFKKSNEKVE 150


>UniRef50_A6CPS0 Carbamoyl-phosphate synthase large subunit n=2 Tax=Bacteria
           RepID=A6CPS0_9BACI
          Length = 167

 Score = 96.9 bits (240), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 24/131 (18%), Positives = 50/131 (38%), Gaps = 12/131 (9%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           +      +     + L   D  K   +   +R   +   + + AT  T +++ R   + V
Sbjct: 22  IVAAGMQMKEYGSVLLTVADKDKDEAIGLAKRFVNI--GYQILATKGTADVL-RTADIPV 78

Query: 61  NAM-LSGPMGGDQQVGALISEGKIDVLIFFWDPLNA--VPHDPDVKALLRLATVWNIPVA 117
             +   G  G    +  +I  G+  ++I   + L     P   D   + R +    IP  
Sbjct: 79  KEVDKIGSEG--PTLLDVIQSGETQLVI---NTLTKGKQPQR-DGFRIRRESVENGIPCL 132

Query: 118 TNVATADFIIQ 128
           T++ TA+ I++
Sbjct: 133 TSLDTAEAILK 143


>UniRef50_A5D508 Carbamoyl-phosphate synthase large chain n=178 Tax=cellular organisms
            RepID=CARB_PELTS
          Length = 1083

 Score = 96.1 bits (238), Expect = 3e-19,   Method: Composition-based stats.
 Identities = 28/140 (20%), Positives = 53/140 (37%), Gaps = 18/140 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M      + +   +     D  K   +S    +  L   + L+AT  T   + +A G+ V
Sbjct: 927  MRAAGLKVASGGRVVFSVADRDKAEAVSIAGEYAAL--GYTLHATPGTARALEKA-GLEV 983

Query: 61   NAM-LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAV-PHDPDVKALLRLATVWNIPVAT 118
              + ++ P+        LI  G + ++I    P     P  P    L R A  + +P  T
Sbjct: 984  EVVEITDPV-------PLIRSGTVGLII--NTPTRGKVPGRP-GFLLRRTAAEYRVPCLT 1033

Query: 119  NVATADFI---IQSPHFNDA 135
            ++ TA  +   ++S  +   
Sbjct: 1034 SLDTARALAMVLRSVRWGGE 1053


>UniRef50_A8V5Q7 Carbamoyl-phosphate synthase large subunit (Fragment) n=1
           Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8V5Q7_9AQUI
          Length = 289

 Score = 85.3 bits (210), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 20/143 (13%), Positives = 46/143 (32%), Gaps = 7/143 (4%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
            T   LP   ++ +   D  K  ++   ++ + L    ++ AT  T   ++    +    
Sbjct: 148 ATGLLLPESGNVFISVADKDKPAVLEIAKKLKSL--GFIILATKGTFKFLTEN-NVEAQL 204

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
           +          +   I  G++ ++I   +  +      D   + R A    +P  T +  
Sbjct: 205 VSKLSE-ERPNIVDKIRNGEVQLII---NTPSGKRERSDAYYIRRAAVEHKVPYFTTIRG 260

Query: 123 ADFIIQSPHFNDAVDILIPDYQR 145
           A     +        I +   Q 
Sbjct: 261 AYAAAVAIQCYKEKGIDVKPIQE 283


>UniRef50_Q58776 Carbamoyl-phosphate synthase large chain, C-terminal section n=10
           Tax=cellular organisms RepID=CARB2_METJA
          Length = 618

 Score = 85.3 bits (210), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 21/130 (16%), Positives = 48/130 (36%), Gaps = 6/130 (4%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                 LP   ++ +   D  K+ ++   ++   L     +YAT  T  ++    G+   
Sbjct: 472 LSANMELPIVGNVFISVRDRDKKHIVDVAKKLHEL--GFTIYATEGTAKVLREN-GIPAI 528

Query: 62  AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            +       +  +  L+ +GK+ ++I   +  +      D   + R A    IP  T + 
Sbjct: 529 LVKKISESPNDNILKLMRDGKMHLII---NTSSGKKAKSDGYYIRRAAVDLGIPYITTIP 585

Query: 122 TADFIIQSPH 131
            A   +++  
Sbjct: 586 GAKAAVKAIE 595


>UniRef50_Q9CKV0 Carbamoyl-phosphate synthase large chain n=6 Tax=cellular organisms
            RepID=CARB_PASMU
          Length = 1068

 Score = 80.3 bits (197), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 25/136 (18%), Positives = 51/136 (37%), Gaps = 8/136 (5%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
                +P    + L  +D  K  L+    + Q     + L AT  T   +    G+ V  +
Sbjct: 929  ANERIPKTGKVFLSVNDADKPRLLPIARQLQE--SGYGLCATLGTAKFLREH-GVAVQII 985

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP-DVKALLRLATVWNIPVATNVAT 122
                 G    +   I  G+I ++I   + ++ +     D  A+ R A    + + T +A 
Sbjct: 986  NKVREG-RPNIVDAIKNGEIAMVI---NTVSGLAETVTDGHAIRRSALQQKVFLQTTLAG 1041

Query: 123  ADFIIQSPHFNDAVDI 138
            A+ +  S  +    ++
Sbjct: 1042 AEALAGSVEYLADSEV 1057


>UniRef50_Q03WW7 Carbamoyl-phosphate synthase large chain n=115 Tax=Bacteria
            RepID=CARB_LEUMM
          Length = 1059

 Score = 78.4 bits (192), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 23/132 (17%), Positives = 46/132 (34%), Gaps = 6/132 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              +   +P   ++     D  K+  +   +R   L     L+AT  TG  +S    + V 
Sbjct: 926  IASNIKVPRYGNVLFTVADDDKEEALELAKRFNDL--GFALFATAGTGAYLSDN-DLPVE 982

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +       +  V AL  + K+ V+I           + D + +   A    +P+ T + 
Sbjct: 983  VLDKISESDNNAVAAL-RQQKVQVVI--NTTQADDRAESDGRLIRNAAIENAVPLFTALD 1039

Query: 122  TADFIIQSPHFN 133
            T    ++     
Sbjct: 1040 TVSAFLEVLESR 1051


>UniRef50_Q8YQL2 Carbamoyl-phosphate synthase large chain n=44 Tax=cellular organisms
            RepID=CARB_ANASP
          Length = 1104

 Score = 78.0 bits (191), Expect = 9e-14,   Method: Composition-based stats.
 Identities = 28/146 (19%), Positives = 50/146 (34%), Gaps = 7/146 (4%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
                LP    + +   D  K   +  V     L     + AT  T  ++    G+NV  +
Sbjct: 965  AGERLPLTGTVFVSMSDRDKSAAVPVVREFIDL--GFKVMATFGTRRVLLEN-GLNVELV 1021

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
            L    G    V   I   KI ++I   +  +      D + + R    + IP+ T +A A
Sbjct: 1022 LKLHEG-RPHVIDAIKNQKIQLII---NTPSGEEAQTDARLIRRTGLAYKIPIITTIAGA 1077

Query: 124  DFIIQSPHFNDAVDILIPDYQRYLAD 149
               + +        + +   Q Y  +
Sbjct: 1078 KATVAAIRSMQNTTLDVKTIQEYCPN 1103


>UniRef50_B0U8L9 Carbamoyl-phosphate synthase, large subunit n=3 Tax=Methylobacterium
            RepID=B0U8L9_METS4
          Length = 1157

 Score = 76.9 bits (188), Expect = 2e-13,   Method: Composition-based stats.
 Identities = 25/143 (17%), Positives = 50/143 (34%), Gaps = 7/143 (4%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            +   +P    + +   D  K  ++  V     +     + ATG T   ++   G+    +
Sbjct: 1019 SGTQVPRAGTVFVSVRDADKARILPAVRMLAEI--GFAILATGGTQRFLAEN-GVAATRI 1075

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
                + G   V   I  G+I ++    +         D ++L R A +  +P  T +A A
Sbjct: 1076 NKV-LEGRPHVVDAIKNGEIHLVF---NTTEGAGALSDSRSLRRAALLHKVPYYTTLAGA 1131

Query: 124  DFIIQSPHFNDAVDILIPDYQRY 146
                +        D+ +   Q Y
Sbjct: 1132 MAAAEGIRAYLGDDLEVRALQEY 1154


>UniRef50_A9QP20 Carbamoyl phosphate synthetase ammonia large chain n=3
            Tax=environmental samples RepID=A9QP20_9EURY
          Length = 1122

 Score = 76.1 bits (186), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 27/134 (20%), Positives = 51/134 (38%), Gaps = 4/134 (2%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              T   +P    + +   +  K  ++   +  + +     +YAT  T +++  + G++V 
Sbjct: 979  LATELPVPTEGGVYITVKNADKHDVIPLAQELEEM--GFTIYATRGTAHVLRDSGGVDVQ 1036

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
                   G       L+ +GKI ++     P N      D   + RLA   NIP  T +A
Sbjct: 1037 TCYRITEGLTPDALDLMRQGKIHLI--LNTPRNTGGAVLDGNMMRRLAVELNIPFVTTMA 1094

Query: 122  TADFIIQSPHFNDA 135
             A   +Q+      
Sbjct: 1095 GARMEVQAIAEAKE 1108


>UniRef50_C3XFR9 Carbamoyl-phosphate synthase subunit large n=1 Tax=Helicobacter bilis
            ATCC 43879 RepID=C3XFR9_9HELI
          Length = 1215

 Score = 74.5 bits (182), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 29/144 (20%), Positives = 55/144 (38%), Gaps = 8/144 (5%)

Query: 8    LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
            LP +  I +   +  K+      +  Q +     + AT  T  ++S A G+   A+L   
Sbjct: 1078 LPKKGKIFISLRNSDKKHAAGLAKTLQEI--GFEIVATLGTHKILSEA-GIEAKAVLKVS 1134

Query: 68   MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
             G    +  +I+  +ID++I   +  +     PD + +       NIP  T ++ A    
Sbjct: 1135 EG-RPHINDMIANHEIDMVI---NTSSNKA-QPDARLIREAVLRANIPYFTTISGAKSAA 1189

Query: 128  QSPHFNDAVDILIPDYQRYLADRL 151
             +   N   +       + L D L
Sbjct: 1190 IAMQANGNDNENTRVSTKALQDYL 1213


>UniRef50_UPI0001B44E07 carbamoyl phosphate synthase large subunit n=8 Tax=Bacteria
           RepID=UPI0001B44E07
          Length = 211

 Score = 74.5 bits (182), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 18/128 (14%), Positives = 44/128 (34%), Gaps = 7/128 (5%)

Query: 2   ELTTRTLPARKHIAL-VAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
               R +   + + L   ++H K   +      + L   +   AT  T   +    G+  
Sbjct: 72  LAAGRHMSDERGVVLATVNNHDKDEFIEIAXDMKEL--GYTFVATEGTAKSLREN-GIEA 128

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
           + +          +   I   ++D++I    P        D   + R A  ++  + T++
Sbjct: 129 DIVNRVEE-SRPNILDAIRNKQVDIVI--NTPTKGNDSTRDGFKIRRTAIEFSTEIMTSL 185

Query: 121 ATADFIIQ 128
            T   +++
Sbjct: 186 DTLKALVE 193


>UniRef50_Q0TM79 Carbamoyl-phosphate synthase large chain n=94 Tax=cellular organisms
            RepID=CARB_CLOP1
          Length = 1067

 Score = 74.5 bits (182), Expect = 9e-13,   Method: Composition-based stats.
 Identities = 28/143 (19%), Positives = 52/143 (36%), Gaps = 9/143 (6%)

Query: 3    LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
             +  T    K I      H K+  M   +    L   +   AT  T   +  A G++   
Sbjct: 931  ASMYTGDKGKTILATIKKHDKKEFMELAKDLDKL--GYNFIATTGTAKELREA-GIDAKE 987

Query: 63   MLSGPMGGD-QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            +    +G +   +  LI   +ID+++    P  A     D   + R A   NI V T++ 
Sbjct: 988  VR--RIGEESPNIMDLIKNKEIDLVV--NTPTKANDSKRDGFHIRRAAIERNIGVMTSLD 1043

Query: 122  TADFIIQSPHFNDAVDILIPDYQ 144
            T   +++      A +  +  + 
Sbjct: 1044 TLKALVE-LQKEGAHNRELEVFN 1065


>UniRef50_C0A8Y6 Carbamoyl-phosphate synthase, large subunit n=2 Tax=Bacteria
            RepID=C0A8Y6_9BACT
          Length = 1133

 Score = 74.2 bits (181), Expect = 1e-12,   Method: Composition-based stats.
 Identities = 22/139 (15%), Positives = 49/139 (35%), Gaps = 7/139 (5%)

Query: 8    LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
            LP   ++ L   D  K+  +    +   L     +Y+T  T   ++   G+ V  +    
Sbjct: 995  LPTGGNVFLSVKDSDKKRAVDLARQLIKL--GFTIYSTSGTAQHLAD-CGVPVTRLAKID 1051

Query: 68   MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
             G    +  +I   +I ++I   +  + +    D   +   A   ++ + T +  A   +
Sbjct: 1052 EGRPNTI-DMIKNNQIQLVI---NTPSGMIPRQDENKIRSAAYAHSVCIMTTITGAFAAL 1107

Query: 128  QSPHFNDAVDILIPDYQRY 146
                   +  I +   Q Y
Sbjct: 1108 SGIKALKSQRIGVRPIQHY 1126


>UniRef50_C0R503 Carbamoyl-phosphate synthase large subunit n=6 Tax=Wolbachia
            RepID=C0R503_WOLWR
          Length = 1151

 Score = 72.2 bits (176), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 26/143 (18%), Positives = 56/143 (39%), Gaps = 7/143 (4%)

Query: 3    LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
                 LP      +   D  K+ ++  V   + L     +YAT  T   ++   G+   A
Sbjct: 1012 AAGYKLPTEGAALVSVKDDDKEYILPVVRMLKEL--SFEIYATKGTALYLNNN-GIAAKA 1068

Query: 63   MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
            +     G    +  ++ +GKI+++I   +    V    D K + R A + NI  +T  + 
Sbjct: 1069 VNKVREG-RPHIVDMLKDGKINLVI---NTSKGVKSVSDSKDIRRTAILQNIAYSTTASG 1124

Query: 123  ADFIIQSPHFNDAVDILIPDYQR 145
            +  ++ +  +     + +   Q+
Sbjct: 1125 SKALVLAIQYVKNSKLEVKSLQQ 1147


>UniRef50_A7HVJ4 Carbamoyl-phosphate synthase, large subunit n=20 Tax=Bacteria
            RepID=A7HVJ4_PARL1
          Length = 1079

 Score = 71.5 bits (174), Expect = 7e-12,   Method: Composition-based stats.
 Identities = 24/143 (16%), Positives = 52/143 (36%), Gaps = 7/143 (4%)

Query: 5    TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML 64
               +P    + +   D  K  +++  ++   +     L ATG T   ++   G+ V  + 
Sbjct: 944  GTKVPVTGTVFVSVKDSDKAKIVAPAKKLLDM--GFKLVATGGTQRYLAEQ-GIEVGTIN 1000

Query: 65   SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
               + G   +   I  G++ ++    +         D  +L R A +  +P  T VA A 
Sbjct: 1001 KV-LEGRPHIVDAIKNGEVALVF---NTTEGAQALSDSMSLRRSALMMKVPYYTTVAGAR 1056

Query: 125  FIIQSPHFNDAVDILIPDYQRYL 147
              ++         + +   Q Y+
Sbjct: 1057 AAVEGIDAIRKGQLEVASLQSYI 1079


>UniRef50_D1Y1S0 Carbamoyl-phosphate synthase, large subunit n=2 Tax=Bacteria
            RepID=D1Y1S0_9BACT
          Length = 1364

 Score = 71.5 bits (174), Expect = 8e-12,   Method: Composition-based stats.
 Identities = 23/154 (14%), Positives = 52/154 (33%), Gaps = 8/154 (5%)

Query: 1    MELTTRTL--PARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGM 58
            +      +       + +   D  K  ++    R   L     LY TG T   +    G+
Sbjct: 937  LIAAGYAVRHHEPGGVLISVQDRDKPEIVELARRLASL--GCRLYTTGGTAEYLKSR-GI 993

Query: 59   NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVAT 118
               ++     G ++ +  L+ +G++  ++    P ++     D + L   A        T
Sbjct: 994  RSASVGKISQG-NRDIPYLLDQGRVQYVLSTSSPDSSE--RADAQVLRSKAIERRAACMT 1050

Query: 119  NVATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
            ++ TA  ++           +      +L DR +
Sbjct: 1051 SLDTARALVDCMVSGYDEGNVELVDMAHLPDRKR 1084


>UniRef50_A9A4K3 Carbamoyl-phosphate synthase, large subunit n=5 Tax=Thaumarchaeota
            RepID=A9A4K3_NITMS
          Length = 1080

 Score = 69.2 bits (168), Expect = 4e-11,   Method: Composition-based stats.
 Identities = 27/153 (17%), Positives = 50/153 (32%), Gaps = 8/153 (5%)

Query: 1    MELTTRTLPARKHIALVAHDHC-KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATG-M 58
            +      LP      +       K+ L+S + + + L     + AT  T        G +
Sbjct: 929  LTSVGIKLPQTGTAVVTVGGTENKEKLLSSIAKLKQL--GFKIMATEHTAEFFEEKVGGI 986

Query: 59   NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAV---PHDPDVKALLRLATVWNIP 115
             +   +S P      +  ++ E KID +I                D   + R A    IP
Sbjct: 987  EIIHKISEPER-LPNIADMLYERKIDFIINIPSTSTIEKYVGMLDDEYQIRRKAIELGIP 1045

Query: 116  VATNVATADFIIQSPHFNDAVDILIPDYQRYLA 148
            V T +  AD  +++  +    +      + Y  
Sbjct: 1046 VLTTIELADSFVKTLEWLQHNETTKDPIEPYDP 1078


>UniRef50_Q3APN7 Carbamoyl-phosphate synthase large subunit n=11 Tax=Chlorobiaceae
           RepID=Q3APN7_CHLCH
          Length = 621

 Score = 68.8 bits (167), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 26/150 (17%), Positives = 53/150 (35%), Gaps = 7/150 (4%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQ-MLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           +     LP    + +  +D  K   +++       +     L AT  T   ++   G+  
Sbjct: 471 QAANMQLPLSGAVFISVNDQDKNHRMLAIARSLYDM--DFDLVATAGTWQFLTDN-GIEC 527

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +      G   +   I  GK+D +I   +         D +A+   + + N+P  T +
Sbjct: 528 KKVYKVGEEGRPNIFDSIKHGKVDFVI---NTPRGEKALHDEEAIGAASVLSNVPFVTTI 584

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADR 150
             A+  +Q+       +  +   Q Y A R
Sbjct: 585 EAAEASVQAIGCIRHQEFGVKSLQEYAAYR 614


>UniRef50_UPI0001C31DA7 carbamoyl-phosphate synthase, large subunit n=1 Tax=Conexibacter
            woesei DSM 14684 RepID=UPI0001C31DA7
          Length = 1042

 Score = 68.8 bits (167), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 24/117 (20%), Positives = 39/117 (33%), Gaps = 9/117 (7%)

Query: 5    TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML 64
               LP+   + +   D  K            L     + AT  T   I R  G+ V A+ 
Sbjct: 893  GSVLPSEGTVFITVTDGDKPAAAGVAMALHGL--GFRIVATAGTAQAIKR-MGIPVEALE 949

Query: 65   SGPMG-GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
               +G G   V  LI  G++ +++   +         D   +   A    IP  T +
Sbjct: 950  K--IGSGSPNVLELIERGEVKLVV---NTPVGTGARIDGWEIRSAAIAAGIPCITTM 1001


>UniRef50_A6LPD9 Carbamoyl-phosphate synthase large chain n=23 Tax=Firmicutes
            RepID=CARB_CLOB8
          Length = 1069

 Score = 68.0 bits (165), Expect = 9e-11,   Method: Composition-based stats.
 Identities = 20/135 (14%), Positives = 44/135 (32%), Gaps = 6/135 (4%)

Query: 10   ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
             +  I    + H K   +   +    +   +   AT  T  L+  A G+ V  +      
Sbjct: 938  EKGKILATINKHDKAEFLPIAKDLASV--GYKFIATSGTCALLKEA-GIEVEEIRKIDE- 993

Query: 70   GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
             +  +  ++   ++D+++    P        D   + R A   N+ V T + T   I   
Sbjct: 994  EEPNILDIVKNREVDLVV--NTPTKGNDSKRDGFLIRRAAVERNLGVITALDTLRAIADV 1051

Query: 130  PHFNDAVDILIPDYQ 144
                   +  +  + 
Sbjct: 1052 ELEKFDENKDLEVFN 1066


>UniRef50_C8PAM0 Carbamoyl-phosphate synthase n=4 Tax=Lactobacillus RepID=C8PAM0_9LACO
          Length = 1055

 Score = 67.2 bits (163), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 27/130 (20%), Positives = 58/130 (44%), Gaps = 6/130 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
            E +  T+P+   + +   D  K+  +S   R   L     L AT  T N+++   G+  +
Sbjct: 923  EASNLTIPSYGTVFISVKDSDKKSAISVAARFHKL--GFQLLATEGTANILAEE-GITTS 979

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G +  +   I++ KI+++I   +  ++  H  D   +   A   +IPV +++ 
Sbjct: 980  IVEKLQTG-NNSLLEKIAQHKINLVINVTNLSDSASH--DAIMIKDQALNTHIPVFSSIQ 1036

Query: 122  TADFIIQSPH 131
            +A+ I+    
Sbjct: 1037 SAENILNVLE 1046


>UniRef50_C9RNJ8 Carbamoyl-phosphate synthase, large subunit n=7 Tax=Bacteria
            RepID=C9RNJ8_FIBSS
          Length = 1072

 Score = 66.5 bits (161), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 26/147 (17%), Positives = 49/147 (33%), Gaps = 8/147 (5%)

Query: 2    ELTTRTLPARKHIALVAHDHCK--QMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMN 59
            E     LP+   + +   D     +  +   +  Q L     +YAT  T      A G+ 
Sbjct: 925  EAAGSFLPSEGAVLISLSDKVNLSEQAIEIGKEFQKL--GFKIYATEGTAKF-YEAAGVK 981

Query: 60   VNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATN 119
               +     G    V  +I   +++++I    P        D  A+ + A  + +P  T 
Sbjct: 982  CEVVNKIAEG-RPNVLDIILNKQVNLII--NTPWAKRDAIKDESAIRKAAIKYKVPYITT 1038

Query: 120  VATADFIIQSPHFNDAVDILIPDYQRY 146
            +A A   ++           +   Q Y
Sbjct: 1039 LAGAYNTVKGIAAARNGHGAVKSLQEY 1065


>UniRef50_Q9KHE9 Carbamoyl phosphate synthetase large subunit (Fragment) n=1
           Tax=Nostoc sp. PCC 7120 RepID=Q9KHE9_ANASP
          Length = 127

 Score = 66.5 bits (161), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 7/130 (5%)

Query: 20  DHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALIS 79
           D  K   +  V     L     + AT  T  ++    G+NV  +L    G    V   I 
Sbjct: 4   DRDKSAAVPVVREFIDL--GFKVMATFGTRRVLLEN-GLNVELVLKLHEG-RPHVIDAIK 59

Query: 80  EGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDIL 139
             KI ++I   +  +      D + + R    + IP+ T +A A   + +        + 
Sbjct: 60  NQKIQLII---NTPSGEEAQTDARLIRRTGLAYKIPIITTIAGAKATVAAIRSMQNTTLD 116

Query: 140 IPDYQRYLAD 149
           +   Q Y  +
Sbjct: 117 VKTIQEYCPN 126


>UniRef50_B9L7I5 Carbamoyl-phosphate synthase, large subunit n=7 Tax=Proteobacteria
            RepID=B9L7I5_NAUPA
          Length = 1090

 Score = 66.5 bits (161), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 26/142 (18%), Positives = 52/142 (36%), Gaps = 7/142 (4%)

Query: 8    LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
            LP    + +   +  K+   +  +  +       + AT  T  +IS A G+    +L   
Sbjct: 956  LPTSGKVFISLTNIDKEFAPALAKALKN--HGFEIVATSGTYKVISEA-GIECERVLKIS 1012

Query: 68   MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
             G    +  +I   +I ++I   +  +      D K + R      IP  T +A A   +
Sbjct: 1013 EG-RPNIVDMIKNEEIALVI---NTSDNKASKDDAKIIRREVLNQGIPYFTTIAAAFAAV 1068

Query: 128  QSPHFNDAVDILIPDYQRYLAD 149
            ++  F    +  +   Q Y  +
Sbjct: 1069 EAIEFLQTSEEKVKSIQDYFKN 1090


>UniRef50_C1A4I5 Carbamoyl-phosphate synthase large chain n=223 Tax=cellular organisms
            RepID=CARB_GEMAT
          Length = 1094

 Score = 66.1 bits (160), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 24/145 (16%), Positives = 45/145 (31%), Gaps = 7/145 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP    +     D  K    S   +   +     + AT  T        G+ V 
Sbjct: 933  LAADNALPREGTVFFTVSDGDKPTAASLAGKFHSI--GFSIMATSGTAAFFREQ-GIPVT 989

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            ++L    G        I  G++ +L+    PL       D + L + A    +P  T + 
Sbjct: 990  SVLKVHEG-RPHGVDKILNGEVQLLV--NTPLGKHA-QVDDEKLRQAAIANRLPYTTTLT 1045

Query: 122  TADFIIQSPHFNDAVDILIPDYQRY 146
             A    ++       + ++   Q +
Sbjct: 1046 AASAAFEAIAARRTREPVVRSLQEW 1070


>UniRef50_B8BWS2 Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BWS2_THAPS
          Length = 1354

 Score = 65.7 bits (159), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 15/76 (19%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            +       + +ALVAH+H +  +  ++E +  +L++  +  T T                
Sbjct: 1266 SKFAPSDMRQLALVAHNHMRPAMKDFIEMYFSILKKFRITGTQT---------------K 1310

Query: 64   LSGPMGGDQQVGALIS 79
            +SGP+GGD QV AL+ 
Sbjct: 1311 ISGPLGGDAQVAALMC 1326


>UniRef50_P07259 Aspartate carbamoyltransferase n=65 Tax=cellular organisms
            RepID=PYR1_YEAST
          Length = 2214

 Score = 65.3 bits (158), Expect = 5e-10,   Method: Composition-based stats.
 Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 19/157 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHC-KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMN 59
            +  T   LP +K+I L    +  KQ L+S V++   +   + L+AT  T + +S   G+ 
Sbjct: 1351 LLATGFKLP-KKNILLSIGSYKEKQELLSSVQKLYNM--GYKLFATSGTADFLSEH-GIA 1406

Query: 60   VNAMLSGPMGGDQQ-----VGALISEGKIDVLIF------FWDPLNAVPHDPDVKALLRL 108
            V  +       D Q     +   ++  +ID+ I       F  P + V          RL
Sbjct: 1407 VQYLEVLNKDDDDQKSEYSLTQHLANNEIDLYINLPSANRFRRPASYVSK---GYKTRRL 1463

Query: 109  ATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
            A  +++P+ TNV  A  +I++   N  +D+   D Q 
Sbjct: 1464 AVDYSVPLVTNVKCAKLLIEAISRNITLDVSERDAQT 1500


>UniRef50_O93937 Aspartate carbamoyltransferase n=344 Tax=cellular organisms
            RepID=PYR1_EMENI
          Length = 2275

 Score = 64.5 bits (156), Expect = 9e-10,   Method: Composition-based stats.
 Identities = 32/157 (20%), Positives = 63/157 (40%), Gaps = 19/157 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP R  +  +     K  ++  + + + +     L+AT  T + +    G+ V
Sbjct: 1391 LLSTGFKLPKRNILLSIGSYKEKMEMLPSIIKLRDV--GFELFATSGTADFLKEN-GVPV 1447

Query: 61   NAMLSGPMGGDQQVGAL------ISEGKIDVLIF------FWDPLNAVPHDPDVKALLRL 108
              +   P G D+ + +       ++   ID+ I       F  P N +          R+
Sbjct: 1448 KYLEILP-GEDEDIKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYMSK---GYRTRRM 1503

Query: 109  ATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
            A  +  P+ TNV  A  +I++   + A+++   DYQ 
Sbjct: 1504 AVDYQTPLVTNVKNAKILIEAIARHYALNVQTIDYQT 1540


>UniRef50_Q2FLD9 Carbamoyl-phosphate synthase large chain n=6 Tax=cellular organisms
            RepID=CARB_METHJ
          Length = 1056

 Score = 63.8 bits (154), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 26/149 (17%), Positives = 54/149 (36%), Gaps = 9/149 (6%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP   ++ +   D  K  ++   +          +YAT  T    +   G+  N
Sbjct: 916  IAAHNRLPKSGNVFISVTDDLKDQILQVAKTFTE--NGLSIYATSGTVEFFAER-GITAN 972

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIF-FWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +     G    V  ++  G+I ++I  F D  +   H    + ++R+A  +  P  T +
Sbjct: 973  LVRKIAEG-SPNVLDMLRAGEISLIINNFADKQSRHDH----QQIMRVAVDYGTPYITTL 1027

Query: 121  ATADFIIQSPHFNDAVDILIPDYQRYLAD 149
              A    ++ +     ++ I   Q Y+  
Sbjct: 1028 QAAVAAAEAINSVREENLTIEPLQHYIGR 1056


>UniRef50_A8F453 Carbamoyl-phosphate synthase large chain n=13 Tax=Bacteria
            RepID=CARB_THELT
          Length = 1105

 Score = 63.8 bits (154), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 24/150 (16%), Positives = 50/150 (33%), Gaps = 18/150 (12%)

Query: 10   ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
            + K + +  +D  K+ ++  V     L     ++AT  TG ++ R+ G+ V  +     G
Sbjct: 948  STKSLLVTVNDRDKREIVPLVSYLYDL--GFEVFATAGTGKIL-RSMGIAVKNVFKVGEG 1004

Query: 70   GDQQVGALISEGKIDVLIFFWDPLNAVPHDPD--------------VKALLRLATVWNIP 115
                V  LI +GKI  ++    P      + +                 +   A    +P
Sbjct: 1005 -KPDVVDLIRQGKIGFIVITQSPNRKTSAEINREAENSFADDERTAGYKIRTAAIQCKVP 1063

Query: 116  VATNVATADFIIQSPHFNDAVDILIPDYQR 145
              T +      + +        + +   Q 
Sbjct: 1064 CITTIEAFRAEVSAIRRLKKSTLSVRSLQD 1093


>UniRef50_A2QRW1 Contig An08c0170, complete genome n=337 Tax=cellular organisms
            RepID=A2QRW1_ASPNC
          Length = 2277

 Score = 63.0 bits (152), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 31/157 (19%), Positives = 62/157 (39%), Gaps = 19/157 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP R  +  +     K  ++  + +   +     L+AT  T + +    G+ V
Sbjct: 1393 LISTGFRLPKRNVLFSIGSYKEKMEMLPSIRKLHQI--GFNLFATSGTADFLKEN-GVPV 1449

Query: 61   NAMLSGPMGGDQQVGAL------ISEGKIDVLIF------FWDPLNAVPHDPDVKALLRL 108
              +   P G ++ + +       ++   ID+ I       F  P N +          R+
Sbjct: 1450 KYLEILP-GEEEDIKSEYSLTQHLANNLIDLYINLPSNNRFRRPANYMSK---GYRTRRM 1505

Query: 109  ATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
            A  +  P+ TNV  A  +I++   + A+++   DYQ 
Sbjct: 1506 AVDYQTPLVTNVKNAKILIEAIARHFALNVQTIDYQT 1542


>UniRef50_B8GEA3 Carbamoyl-phosphate synthase large chain n=2 Tax=Euryarchaeota
            RepID=CARB_METPE
          Length = 1056

 Score = 63.0 bits (152), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 21/120 (17%), Positives = 44/120 (36%), Gaps = 7/120 (5%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP   ++ +      K+ +     + + L     L+ T  T   + +A G+  N
Sbjct: 914  ISADNELPIEGNVFISVSTEQKEEVRRIAAQLRDL--GLTLFGTKGTVETLMQA-GIEAN 970

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    V  ++ +G+I ++I   +         D   ++R A  + IP  T + 
Sbjct: 971  LVRKVQEG-SPNVIDMVRKGEIRLII---NTPVDKQSRLDHYQIMRAAVDYGIPYITTLQ 1026


>UniRef50_UPI000197805F carbamoyl phosphate synthase large subunit n=3 Tax=Campylobacterales
            RepID=UPI000197805F
          Length = 1232

 Score = 62.2 bits (150), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 25/144 (17%), Positives = 47/144 (32%), Gaps = 8/144 (5%)

Query: 6    RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLS 65
              LP    + L      K+  ++       L     + AT  T  ++    G+  + +L 
Sbjct: 1095 NALPLSGEVFLSLASLDKKEGVALANDFIEL--GFSICATEGTYKILCEN-GIEASHILK 1151

Query: 66   GPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADF 125
               G    +   +   +I + I   D L+      D   +       +IP  T +A A  
Sbjct: 1152 VSEG-RPNIIDRMMNNQIALAINTSDNLSNK---DDTHLIRTQIIKSSIPYFTTLAAARV 1207

Query: 126  IIQSPHFNDAVDILIP-DYQRYLA 148
             I++       ++      Q YL 
Sbjct: 1208 AIEAIRDIKKYNLSQAFSLQEYLE 1231


>UniRef50_O50236 Carbamoyl-phosphate synthase large chain n=3 Tax=Zymomonas mobilis
            RepID=CARB_ZYMMO
          Length = 1112

 Score = 61.8 bits (149), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 24/145 (16%), Positives = 47/145 (32%), Gaps = 7/145 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP      +   D  K  ++  ++    L     L AT  T   +    G+ V 
Sbjct: 969  LAAGNALPRAGTFFISVKDSDKAQIVEPIKALTDL--GIKLVATDGTARYLQSK-GVPVE 1025

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    +  LI +G I +++   +         D  ++     +  +P  T  A
Sbjct: 1026 RVNKVREG-RPHIVDLIKDGAISLVV---NTTEGWQSLQDSASIRSSVVLAPVPYFTTAA 1081

Query: 122  TADFIIQSPHFNDAVDILIPDYQRY 146
             A    ++     A ++ +   Q Y
Sbjct: 1082 AAIVAAEAIVAIKARELEVRSLQSY 1106


>UniRef50_Q1GA90 Carbamoyl-phosphate synthase, large chain n=28 Tax=Lactobacillus
            RepID=Q1GA90_LACDA
          Length = 1063

 Score = 61.8 bits (149), Expect = 6e-09,   Method: Composition-based stats.
 Identities = 24/130 (18%), Positives = 50/130 (38%), Gaps = 6/130 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
            E +   +P+   I     D  KQ + +  +R   L     + AT  T N+++ A G+   
Sbjct: 931  EASDLHIPSYGTIFFSVSDEEKQEVANLAKRFARL--GFKITATEGTANILAEA-GITTG 987

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    +   I   +I +++   + L+    +  +K   +      IPV +++ 
Sbjct: 988  VIAKIQEGSR-NLLERIQTHRIVMVVNVVN-LSDSAVEDSIKIKDQALNTH-IPVFSSLE 1044

Query: 122  TADFIIQSPH 131
            T   I+    
Sbjct: 1045 TVQLILDVLE 1054


>UniRef50_UPI00017430FF carbamoyl phosphate synthase large subunit n=1 Tax=candidate
           division TM7 single-cell isolate TM7a
           RepID=UPI00017430FF
          Length = 104

 Score = 61.4 bits (148), Expect = 8e-09,   Method: Composition-based stats.
 Identities = 19/96 (19%), Positives = 37/96 (38%), Gaps = 7/96 (7%)

Query: 39  QHVLYATGTTGNLISRATGMNVNAMLSGPMGG--DQQVGALISEGKIDVLIFFWDPLNAV 96
            + + AT  T        G++V  +      G  +  V  LI +G +D++I   +     
Sbjct: 4   GYHIMATKGTAKYFEDK-GLHVETVGKIDEEGIYEHDVLGLIYKGLVDMVI---NTAAKK 59

Query: 97  PH-DPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
                D   + R A+   I   T++ T D +++   
Sbjct: 60  KTARNDGFKIRRAASEQEIACLTSLDTTDALLKVLE 95


>UniRef50_Q8UDE9 Carbamoyl-phosphate synthase large chain n=103 Tax=Proteobacteria
            RepID=CARB_AGRT5
          Length = 1162

 Score = 61.1 bits (147), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 20/117 (17%), Positives = 44/117 (37%), Gaps = 7/117 (5%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
                LP    + +   D  K+ ++S +     +     + ATG T   ++   G+N   +
Sbjct: 1025 AGVDLPRSGTVFVSVRDEDKEGVLSAIR--ILVESGFKVLATGGTQRFLAEQ-GINAEKI 1081

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
                 G    +   I   ++ ++I   +  ++     D K+L R   +  +P  T +
Sbjct: 1082 NKVQEG-RPHIEDAIRNRQVQLVI---NTTDSNKAISDSKSLRRATLMQKVPYYTTM 1134


>UniRef50_P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial n=86
            Tax=Deuterostomia RepID=CPSM_HUMAN
          Length = 1500

 Score = 61.1 bits (147), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 31/155 (20%), Positives = 58/155 (37%), Gaps = 11/155 (7%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  T   +P +  I +      +   +   E+     E   L+AT  T + ++ A  +  
Sbjct: 1350 MLSTGFKIPQKG-ILIGIQQSFRPRFLGVAEQLHN--EGFKLFATEATSDWLN-ANNVPA 1405

Query: 61   NAML-SGPMGGDQQVGA---LISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPV 116
              +      G +  + +   LI +G ID++I   +      H  D   + R A    IP+
Sbjct: 1406 TPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVH--DNYVIRRTAVDSGIPL 1463

Query: 117  ATNVATADFIIQSPHFNDAVDILIP-DYQRYLADR 150
             TN        ++   +  VD      Y++Y A +
Sbjct: 1464 LTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGK 1498


>UniRef50_B7G8W8 Predicted protein n=7 Tax=cellular organisms RepID=B7G8W8_PHATR
          Length = 1542

 Score = 60.7 bits (146), Expect = 1e-08,   Method: Composition-based stats.
 Identities = 26/148 (17%), Positives = 49/148 (33%), Gaps = 7/148 (4%)

Query: 1    MELTTRTLP-ARKHIAL-VAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGM 58
            M  TT  LP   + I L +A +  ++           L   + L+ T  T        G+
Sbjct: 1357 MLSTTFKLPNKNRTILLSIASEEYRREFAEAAVILHRL--GYKLFGTPGTAAYYQDNHGI 1414

Query: 59   NVNAMLSGPMGGDQQVGA---LISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIP 115
             + ++       D   G     I  GKID++I   +             + R    + + 
Sbjct: 1415 EIKSVSKPDAETDDAPGTALHEIKNGKIDLVINVSEGATRREEITSGYIIRRAVVDFGVS 1474

Query: 116  VATNVATADFIIQSPHFNDAVDILIPDY 143
            + T+V  A  + +           +P +
Sbjct: 1475 LVTDVKCAIKLAECFDRGMGDGKFVPRH 1502


>UniRef50_A8JIR0 Carbamoyl phosphate synthase, large subunit n=1 Tax=Chlamydomonas
            reinhardtii RepID=A8JIR0_CHLRE
          Length = 1075

 Score = 60.3 bits (145), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 25/120 (20%), Positives = 43/120 (35%), Gaps = 12/120 (10%)

Query: 5    TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML 64
             + LP    + +   D  K  ++        L     L AT  T   + R  G+    + 
Sbjct: 926  GQKLPKTGKVFVSMADKYKPDIIEIARNLGNL--GFGLVATTGTALAL-RNAGVPCEQVF 982

Query: 65   SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPD---VKALLRLATVWNIPVATNVA 121
                G       L+  G++ +++     + +   + D    K L RLA   +IP  T VA
Sbjct: 983  KIQEG-RPNPADLMRNGEVTLMM-----MTSGGDEADLRDGKELRRLALQLSIPTVTTVA 1036


>UniRef50_C0AZ23 Putative uncharacterized protein n=1 Tax=Proteus penneri ATCC 35198
           RepID=C0AZ23_9ENTR
          Length = 165

 Score = 57.6 bits (138), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 21/120 (17%), Positives = 43/120 (35%), Gaps = 7/120 (5%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M  +  T+  +    L   +  K+ ++    +   L     L AT  T  ++  A G+N 
Sbjct: 22  MLGSNSTMKKKGRALLSVREGDKKRVVDLATKL--LKSGFELDATHGTAIVLGEA-GINP 78

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +     G    +   I  G+ D ++   +  +      D K + R A  + +   T +
Sbjct: 79  RLVNKVHEG-RPHIEDRIKNGEYDYIV---NTTSGRQAIEDSKIIRRSALRYKVHYDTTL 134


>UniRef50_B3LBP4 Carbamoyl phosphate synthetase, putative n=6 Tax=Plasmodium
            RepID=B3LBP4_PLAKH
          Length = 2169

 Score = 57.2 bits (137), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 30/149 (20%), Positives = 58/149 (38%), Gaps = 23/149 (15%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPL-LEQHVLYATGTT----------- 48
            +  T   LP +K I +   +   +  +++ E  Q L L    +YAT  T           
Sbjct: 2005 LIATGMKLP-KKSILISIKNLNNK--LAFEEPFQLLFLMGFTIYATEGTYDFYSKFLESF 2061

Query: 49   ----GNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKA 104
                G+   +   + V+   S  +     +  LI   K++++I   D L       +   
Sbjct: 2062 NVTKGSKFHQRL-IRVHNKSSENL--MPNITDLIMNHKVEMVINITDTLKTKV-SSNGYK 2117

Query: 105  LLRLATVWNIPVATNVATADFIIQSPHFN 133
            + RLA+ + +P+ TN+  +   I S +  
Sbjct: 2118 IRRLASDFQVPLITNMKLSSLFIDSLYRK 2146


>UniRef50_C5JG53 Bifunctional pyrimidine biosynthesis protein pyrABCN n=1
            Tax=Ajellomyces dermatitidis SLH14081 RepID=C5JG53_AJEDS
          Length = 2544

 Score = 56.8 bits (136), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 26/146 (17%), Positives = 56/146 (38%), Gaps = 21/146 (14%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP +  +  +     K  ++  + +   L   + L+AT  T + +    G+ V
Sbjct: 1668 LISTGFKLPKKNVLFSIGSFKEKVEMLPSIRKLHAL--GYNLFATAGTADYLKEH-GLPV 1724

Query: 61   NAMLSGPMGGDQQ-------VGALISEGKIDVLIF------FWDPLNAVPHDPDVKALLR 107
              +    + G+++       +   ++   ID+ I       F  P N +          R
Sbjct: 1725 KYLEV--LAGEEEDLKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYMSK---GYRTRR 1779

Query: 108  LATVWNIPVATNVATADFIIQSPHFN 133
            +A  +  P+ TNV  A  +I++   +
Sbjct: 1780 MAVDYQTPLVTNVKNAKILIEAIARH 1805


>UniRef50_C0NSX2 Carbamoyl-phosphate synthase n=3 Tax=cellular organisms
            RepID=C0NSX2_AJECG
          Length = 2496

 Score = 56.1 bits (134), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 26/146 (17%), Positives = 56/146 (38%), Gaps = 21/146 (14%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP +  +  +     K  ++  + +   L   + L+AT  T + +    G+ V
Sbjct: 1620 LISTGFKLPNKNVLFSIGSFKEKVEMLPSIRKLHAL--GYNLFATAGTADYLKEH-GLPV 1676

Query: 61   NAMLSGPMGGDQQ-------VGALISEGKIDVLIF------FWDPLNAVPHDPDVKALLR 107
              +    + G+++       +   ++   ID+ I       F  P N +          R
Sbjct: 1677 KYLDV--LAGEEEDLKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYMSK---GYRTRR 1731

Query: 108  LATVWNIPVATNVATADFIIQSPHFN 133
            +A  +  P+ TNV  A  +I++   +
Sbjct: 1732 MAVDYQTPLVTNVKNAKLLIEAIARH 1757


>UniRef50_C6XKE0 MGS domain protein n=1 Tax=Hirschia baltica ATCC 49814
           RepID=C6XKE0_HIRBI
          Length = 493

 Score = 56.1 bits (134), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 26/128 (20%), Positives = 42/128 (32%), Gaps = 8/128 (6%)

Query: 1   MELTTRTLPARKHIALVA-HDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMN 59
           M    R     + + + A     KQ L+        +     ++AT  T   +  A  + 
Sbjct: 19  MLSKGR----ERALLISAGSPDDKQFLLESCRNMADI--GVNIFATPGT-QRLFEAQNIK 71

Query: 60  VNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATN 119
            +       G    +  LI  G+ID +I             D K +  LA    IP+ T+
Sbjct: 72  SSPAHKISSGTQPNIKNLIENGEIDFVINILTGEQDYDEGSDAKQIRSLAIKHGIPLITD 131

Query: 120 VATADFII 127
              A   I
Sbjct: 132 REVARETI 139


>UniRef50_Q9ZKT2 Carbamoyl-phosphate synthase large chain n=422 Tax=cellular organisms
            RepID=CARB_HELPJ
          Length = 1085

 Score = 55.7 bits (133), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 28/139 (20%), Positives = 53/139 (38%), Gaps = 11/139 (7%)

Query: 11   RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGG 70
            +  I +   D  K+     ++R   L     L  T  T   + +A G+    +L    G 
Sbjct: 957  KGLIFVSIKDKDKEEACVLMKRLVEL--GFELCTTEGTHKALEKA-GVKSLKVLKISEG- 1012

Query: 71   DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWN-IPVATNVATADFIIQS 129
               +  L+  G+I + I   D         D K L+R + + N +   T ++  + ++ +
Sbjct: 1013 RPNIMDLMMNGEISMAINTSD----HKSQDDAK-LIRASVLKNHVSYFTTLSAIEVLLLA 1067

Query: 130  PHFNDAVDILIPDYQRYLA 148
               +   D L+   Q YL 
Sbjct: 1068 LEESSQEDELL-ALQDYLK 1085


>UniRef50_Q17XX3 Carbamoyl-phosphate synthase large chain n=7 Tax=Helicobacter
            RepID=Q17XX3_HELAH
          Length = 1133

 Score = 55.7 bits (133), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 26/140 (18%), Positives = 53/140 (37%), Gaps = 13/140 (9%)

Query: 11   RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG- 69
            +  I +   D  K+     ++R   L     L AT  T   + +A    V ++    +  
Sbjct: 1005 KGLIFVSIKDKDKEEACVLMKRLVQL--GFELCATEGTHKALEKA---RVKSLKVLKISE 1059

Query: 70   GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWN-IPVATNVATADFIIQ 128
            G   +  L+  G+I + I   D         D K L+R + + N +   T ++  + ++ 
Sbjct: 1060 GRPNIMDLMMNGEISMAINTSD----HKSQDDAK-LIRASVLKNHVSYFTTLSAIEVLLL 1114

Query: 129  SPHFNDAVDILIPDYQRYLA 148
            +   +   +  +   Q YL 
Sbjct: 1115 ALEES-PEEDALLALQDYLK 1133


>UniRef50_Q8IEN3 Carbamoyl phosphate synthetase n=3 Tax=Eukaryota RepID=Q8IEN3_PLAF7
          Length = 2375

 Score = 55.3 bits (132), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 28/156 (17%), Positives = 58/156 (37%), Gaps = 17/156 (10%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPL-LEQHVLYATGTTGNL---ISRAT 56
            +  T   LP +K I +   +   +  +++ E  Q L L    +YAT  T +       + 
Sbjct: 2211 LIATGMKLP-KKSILISIKNLNNK--LAFEEPFQLLFLMGFTIYATEGTYDFYSKFLESF 2267

Query: 57   GMNV-----NAMLSGPMGGDQQVG----ALISEGKIDVLIFFWDPLNAVPHDPDVKALLR 107
             +N        ++       + +      LI   K++++I   D L       +   + R
Sbjct: 2268 NVNKGSKFHQRLIKVHNKNAENISPNTTDLIMNHKVEMVINITDTLKTKV-SSNGYKIRR 2326

Query: 108  LATVWNIPVATNVATADFIIQSPHFNDAVDILIPDY 143
            LA+ + +P+ TN+      I S +   +       +
Sbjct: 2327 LASDFQVPLITNMKLCSLFIDSLYRKFSRQKERKSF 2362


>UniRef50_D2LJN2 MGS domain protein n=1 Tax=Rhodomicrobium vannielii ATCC 17100
           RepID=D2LJN2_RHOVA
          Length = 481

 Score = 51.8 bits (123), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 22/124 (17%), Positives = 50/124 (40%), Gaps = 4/124 (3%)

Query: 10  ARKHIALVA-HDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM 68
           +RK + + A  +  K  ++  +++   L  +  ++AT  T   ++R  G++   +     
Sbjct: 21  SRKKVLISAGKEDDKARMLPAIKQFLSL--EVDVFATPGTHRFLTRH-GIDTVEIHKITD 77

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
           G    +   ++E + D++I      N      D K + +L     IP+ T+       +Q
Sbjct: 78  GRAPNIRTFLNENRFDLVINVLTGDNDYDESSDAKLIRKLCIENGIPLITDCDVGIETLQ 137

Query: 129 SPHF 132
               
Sbjct: 138 QIVR 141


>UniRef50_A9V282 Predicted protein n=2 Tax=cellular organisms RepID=A9V282_MONBE
          Length = 1920

 Score = 50.3 bits (119), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 25/142 (17%), Positives = 51/142 (35%), Gaps = 13/142 (9%)

Query: 1    MELTTRTLP-ARKHIALVAHDHC-KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGM 58
            M  T+  LP  + ++ L    +  K   +    R Q L     L+ +  T +    + G+
Sbjct: 1076 MISTSFRLPRPQGNVLLSIGGYDGKLEFLDSTRRLQQL--GFKLFGSMGTADFYL-SHGV 1132

Query: 59   NVNAMLSGPMGGDQQ-VGALISEGKIDVLIFFWDPLNAVPHDP-----DVKALLRLATVW 112
             +  +       D + +   + +G  D++I    P+      P           R+A   
Sbjct: 1133 EIKPVDWLADTEDIESIKDNLLDGHYDMVINL--PMRNKYRRPASYMTSGSLARRMAVES 1190

Query: 113  NIPVATNVATADFIIQSPHFND 134
             +P+ TN+  A   I +    +
Sbjct: 1191 KVPLITNIKCAKLFIAALGSEN 1212


>UniRef50_C5KGZ1 Putative uncharacterized protein n=1 Tax=Perkinsus marinus ATCC 50983
            RepID=C5KGZ1_9ALVE
          Length = 1533

 Score = 49.1 bits (116), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 26/134 (19%), Positives = 50/134 (37%), Gaps = 8/134 (5%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATG---M 58
                 TLP +  +  +  +  K+  + W      L   + L+AT +T  ++         
Sbjct: 1402 LSAGYTLPTKTILVSIGPEQQKEEFLPWASILISL--GYHLFATRSTYQVMKDKLNPSQS 1459

Query: 59   NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVP-HDPDVKALLRLATVWNIPVA 117
            ++  +       +  V  LI  GKID+ I    P +A      +   + RLA      + 
Sbjct: 1460 SLTLVYKPYARREPNVKTLIQNGKIDMCIVI--PSSADSCAITEGFEMRRLAVDTRTALI 1517

Query: 118  TNVATADFIIQSPH 131
             ++  A F++ S  
Sbjct: 1518 NDIKEATFLVLSLE 1531


>UniRef50_P05990 Dihydroorotase n=643 Tax=cellular organisms RepID=PYR1_DROME
          Length = 2224

 Score = 48.7 bits (115), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 27/152 (17%), Positives = 57/152 (37%), Gaps = 19/152 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  T   +P    +  +     K  L+  +     +   + LYA+  TG+  +   G+NV
Sbjct: 1317 MMSTGFQIPKNAVLLSIGSFKHKMELLPSIRDLAKM--GYKLYASMGTGDFYAEH-GVNV 1373

Query: 61   NAM-----LSGPM---GGDQQVGALISEGKIDVLIFFWDPLNAVPHD------PDVKALL 106
             ++      + P    G  + +   ++  + D++I    P++                  
Sbjct: 1374 ESVQWTFDKTTPDDINGELRHLAEFLANKQFDLVINL--PMSGGGARRVSSFMTHGYRTR 1431

Query: 107  RLATVWNIPVATNVATADFIIQSPHFNDAVDI 138
            RLA  ++IP+ T+V     +++S   N     
Sbjct: 1432 RLAVDYSIPLVTDVKCTKLLVESMRMNGGKPP 1463


>UniRef50_B8DTW3 Carbamoyl-phosphate synthase large chain n=400 Tax=cellular organisms
            RepID=CARB_BIFA0
          Length = 1136

 Score = 48.7 bits (115), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 28/159 (17%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 8    LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
            LP   ++ +  +D  K+ L  +  R   L     ++AT  T +++ R  G+    +    
Sbjct: 966  LPTNGNVFISVNDTDKRQLPLFAVRLVEL--GFEIWATEGTASVLRR-YGIESKIVDKIH 1022

Query: 68   MGGD-----------------QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLAT 110
               D                 + V  LI EG+ID+++   +  N+     D  ++   A 
Sbjct: 1023 SRVDTDPEHPIEIQHAAGSVGKNVVELIEEGQIDLIL---NTPNSRGSRSDGYSIRAAAI 1079

Query: 111  VWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLAD 149
              +IP  T +     ++ +       D  +   Q +  +
Sbjct: 1080 AADIPQYTTMTEFSAVLLAIEAVKKNDYEVMSIQEHSRE 1118


>UniRef50_B6KSM2 Carbamoyl phosphate synthetase II n=4 Tax=Toxoplasma gondii
            RepID=B6KSM2_TOXGO
          Length = 1699

 Score = 48.7 bits (115), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 31/192 (16%), Positives = 61/192 (31%), Gaps = 52/192 (27%)

Query: 1    MELTTRTLP-ARKHIALVAHDH-CKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA--- 55
            +      LP  ++ I + A     K  L  + +    L     +YAT  T   +  +   
Sbjct: 1498 LISAGVPLPLEKRTILISAGPLWSKMELEPYFKILLDL--GFTIYATEGTYRFLMNSVVR 1555

Query: 56   ---------------TGMN--------------------VNAMLS-------GPMGGDQQ 73
                           +G+                     +  +            GG Q 
Sbjct: 1556 GQGTHLPGNASPASDSGLRTPTTAESDADACICAKYASRIIRVRKPIVGSNESHNGGHQS 1615

Query: 74   --VGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
                +LI  GK++++I   D +N      +   + R AT   +P+ TNV  A   +++ +
Sbjct: 1616 PHALSLIESGKVEMVINVPDSMNHRA-ATNGYLMRRTATDCGVPLLTNVKVASMFVEALN 1674

Query: 132  FNDAVDILIPDY 143
              +A +     +
Sbjct: 1675 KKEAKEAQGRSF 1686


>UniRef50_Q1RKZ5 IP15551p (Fragment) n=1 Tax=Drosophila melanogaster
           RepID=Q1RKZ5_DROME
          Length = 746

 Score = 48.0 bits (113), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 27/152 (17%), Positives = 57/152 (37%), Gaps = 19/152 (12%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M  T   +P    +  +     K  L+  +     +   + LYA+  TG+  +   G+NV
Sbjct: 83  MMSTGFQIPKNAVLLSIGSFKHKMELLPSIRDLAKM--GYKLYASMGTGDFYAEH-GVNV 139

Query: 61  NAM-----LSGPM---GGDQQVGALISEGKIDVLIFFWDPLNAVPHD------PDVKALL 106
            ++      + P    G  + +   ++  + D++I    P++                  
Sbjct: 140 ESVQWTFDKTTPDDINGELRHLAEFLANKQFDLVINL--PMSGGGARRVSSFMTHGYRTR 197

Query: 107 RLATVWNIPVATNVATADFIIQSPHFNDAVDI 138
           RLA  ++IP+ T+V     +++S   N     
Sbjct: 198 RLAVDYSIPLVTDVKCTKLLVESMRMNGGKPP 229


>UniRef50_C1TLQ6 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Dethiosulfovibrio
            peptidovorans DSM 11002 RepID=C1TLQ6_9BACT
          Length = 1044

 Score = 47.6 bits (112), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 17/127 (13%), Positives = 42/127 (33%), Gaps = 10/127 (7%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
               ++P +  +     D  K    +     +   +   +  T  T    SR     V+  
Sbjct: 925  AGWSVPRKGRVLFSVDDGKKAEACAIAALFES--KGWEVEGTPGTAYFFSR---WGVSCR 979

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
                  G   + A +++G+ D+++    P   +    +   + R A   + P   ++  A
Sbjct: 980  SVVKKDG---LSASLNDGRWDLVVNLPGP--DLGAIKEGAGIRRNAMETSTPCLFSLEAA 1034

Query: 124  DFIIQSP 130
              +  + 
Sbjct: 1035 SAVAMAL 1041


>UniRef50_UPI000194C4F6 PREDICTED: similar to carbamoylphosphate synthetase 2/aspartate
            transcarbamylase/dihydroorotase, partial n=1
            Tax=Taeniopygia guttata RepID=UPI000194C4F6
          Length = 1899

 Score = 43.3 bits (101), Expect = 0.002,   Method: Composition-based stats.
 Identities = 25/153 (16%), Positives = 55/153 (35%), Gaps = 19/153 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHC-KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMN 59
            M  T   +P +K+I L    +  K  L+  V   + L   + LYA+  T +  +   G+ 
Sbjct: 1036 MLSTGFKIP-KKNILLTIGSYKNKSELLPTVRTLENL--GYNLYASLGTADFYTEH-GIK 1091

Query: 60   VNAM----------LSGPMGGDQQVGALISEGKIDVLIFF--WDPLNAV--PHDPDVKAL 105
            V A+           +G     + +   ++E   +++I     +                
Sbjct: 1092 VKAVDWHFEEADSSEAGARETQRSILDYLAENHFEMVINLSMRNSGGRRLSSFVTKGYRT 1151

Query: 106  LRLATVWNIPVATNVATADFIIQSPHFNDAVDI 138
             RLA  +++P+  ++      +++     A   
Sbjct: 1152 RRLAVDYSVPLIIDIKCTKLFVEALGQIGAAPP 1184


>UniRef50_B2KDJ0 Carbamoyl-phosphate synthase, large subunit n=10 Tax=Bacteria
            RepID=B2KDJ0_ELUMP
          Length = 1102

 Score = 43.3 bits (101), Expect = 0.003,   Method: Composition-based stats.
 Identities = 23/129 (17%), Positives = 48/129 (37%), Gaps = 7/129 (5%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            ME T   +P +  +     +  K   M  ++          +YAT  T N +    G + 
Sbjct: 965  MESTHIKMPKKGILLSTGREKDKIKFMEVIDNVYKF--GLPVYATLGTANYLKEH-GYDA 1021

Query: 61   NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
              ++      D +   +I + K+D ++     L     + +  A+ + A   N  + TN+
Sbjct: 1022 IPVMYHH---DPKPVDVIKQRKVDFVVNVHKSLELDELEHN-SAIRKTAVKSNCSLLTNL 1077

Query: 121  ATADFIIQS 129
              A    ++
Sbjct: 1078 EKAIAYFKA 1086


>UniRef50_D2RG70 MGS domain protein n=1 Tax=Archaeoglobus profundus DSM 5631
           RepID=D2RG70_ARCPR
          Length = 155

 Score = 41.4 bits (96), Expect = 0.009,   Method: Composition-based stats.
 Identities = 21/132 (15%), Positives = 40/132 (30%), Gaps = 16/132 (12%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSG---PM 68
            ++ +      K  L  + +    L   + LYAT  T   +    G+ V  +        
Sbjct: 1   MNVLISV--SRKDKLERFAKALVNL--GYTLYATEGTAKFL-ENCGIPVRRLSEITHLSE 55

Query: 69  GGD-----QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
             D      +V   I  G   +++     L     D    AL+R      +PV       
Sbjct: 56  SEDLKTLHPEVFKRIYGGFFSLIVVN---LYEDKVDVGGVALIRAGIKAGVPVVCYPEDY 112

Query: 124 DFIIQSPHFNDA 135
           + +++       
Sbjct: 113 EKVLEDLKNGRD 124


>UniRef50_D1B6T5 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Thermanaerovibrio
            acidaminovorans DSM 6589 RepID=D1B6T5_THEAS
          Length = 1049

 Score = 39.1 bits (90), Expect = 0.039,   Method: Composition-based stats.
 Identities = 18/97 (18%), Positives = 32/97 (32%), Gaps = 11/97 (11%)

Query: 39   QHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPH 98
               +Y T  T   + R  G+    +   P+ G   +G  +  G++  ++    PL    +
Sbjct: 958  GCPIYGTPGTCGRLVR-VGVPCRRV--DPLEG---IG--MVGGEVGWVVNTRSPLEDRGY 1009

Query: 99   DPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDA 135
                  L R A        T V T   + Q+      
Sbjct: 1010 ---GFELRRRAAEVGALCVTRVDTLVGLAQALSLGRG 1043


>UniRef50_UPI0000384730 COG0313: Predicted methyltransferases n=1 Tax=Magnetospirillum
           magnetotacticum MS-1 RepID=UPI0000384730
          Length = 298

 Score = 38.3 bits (88), Expect = 0.070,   Method: Composition-based stats.
 Identities = 23/116 (19%), Positives = 41/116 (35%), Gaps = 13/116 (11%)

Query: 26  LMSWVERHQPLLEQHVLYA---TGTTGNLISRATGMNVNAMLSGPM----GGDQQVGALI 78
           L     R   +L    L A   T  TG  + +  G+  + +              + A +
Sbjct: 34  LGDITLRALEVLGHADLVACEDTRVTGR-LMQLLGLK-SPLTPYHDHNADKARPALLARL 91

Query: 79  SEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFND 134
             G++  L+   D    +  DP    L+R     NIPV T +  A  ++ +   + 
Sbjct: 92  GRGEVVALV--SDAGTPMVSDP-GFKLVRDCIESNIPV-TALPGASAVLTALQLSG 143


Searching..................................................done


Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

UniRef50_B7UN42 Methylglyoxal synthase n=174 Tax=Bacteria RepID=...   194   6e-49
UniRef50_B5XY41 Methylglyoxal synthase n=65 Tax=Gammaproteobacte...   186   2e-46
UniRef50_Q4QJW2 Methylglyoxal synthase n=45 Tax=cellular organis...   175   3e-43
UniRef50_B8I1E7 Methylglyoxal synthase n=13 Tax=Firmicutes RepID...   173   2e-42
UniRef50_Q72NU6 Methylglyoxal synthase n=20 Tax=Bacteria RepID=M...   170   1e-41
UniRef50_B9MRV5 Methylglyoxal synthase n=158 Tax=cellular organi...   170   1e-41
UniRef50_Q2SK75 Methylglyoxal synthase n=2 Tax=Gammaproteobacter...   170   1e-41
UniRef50_A4BFH8 Methylglyoxal synthase n=1 Tax=Reinekea blandens...   169   2e-41
UniRef50_A9KFK7 Methylglyoxal synthase n=6 Tax=Coxiella burnetii...   169   3e-41
UniRef50_UPI0001745D5F methylglyoxal synthase n=1 Tax=Verrucomic...   166   1e-40
UniRef50_Q1QX97 Methylglyoxal synthase n=4 Tax=Bacteria RepID=Q1...   165   4e-40
UniRef50_A0LVE0 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A0...   165   4e-40
UniRef50_B0KAD1 Methylglyoxal synthase n=27 Tax=cellular organis...   164   9e-40
UniRef50_C6BZQ4 Methylglyoxal synthase n=7 Tax=Bacteria RepID=MG...   161   7e-39
UniRef50_A4IQ66 Methylglyoxal synthase n=37 Tax=Bacteria RepID=M...   160   2e-38
UniRef50_C9KKW1 Methylglyoxal synthase n=1 Tax=Mitsuokella multa...   154   1e-36
UniRef50_C1TMX7 Methylglyoxal synthase n=1 Tax=Dethiosulfovibrio...   152   3e-36
UniRef50_D0MG34 Methylglyoxal synthase n=1 Tax=Rhodothermus mari...   152   3e-36
UniRef50_B1YKL9 Methylglyoxal synthase n=78 Tax=Bacteria RepID=M...   152   4e-36
UniRef50_C2HDU2 Methylglyoxal synthase n=12 Tax=Enterococcus fae...   150   1e-35
UniRef50_Q10YJ6 Cyclic nucleotide-binding protein n=2 Tax=Bacter...   150   1e-35
UniRef50_Q3AGN5 Cyclic nucleotide-binding domain (CNMP-BD) prote...   150   1e-35
UniRef50_Q72HP3 Methylglyoxal synthase n=3 Tax=Bacteria RepID=MG...   148   4e-35
UniRef50_Q8UIV6 Methylglyoxal synthase n=8 Tax=Alphaproteobacter...   148   4e-35
UniRef50_Q55452 Uncharacterized protein sll0036 n=7 Tax=Bacteria...   147   9e-35
UniRef50_D2BG68 Methylglyoxal synthase n=5 Tax=Dehalococcoides R...   146   3e-34
UniRef50_UPI0000E11027 methylglyoxal synthase n=1 Tax=Rhodobacte...   145   4e-34
UniRef50_C4ZA41 Methylglyoxal synthase n=10 Tax=Firmicutes RepID...   144   7e-34
UniRef50_Q2RSM7 Methylglyoxal synthase n=1 Tax=Rhodospirillum ru...   144   9e-34
UniRef50_C3MBY3 Methylglyoxal synthase n=5 Tax=Alphaproteobacter...   144   1e-33
UniRef50_A6L618 Methylglyoxal synthase n=34 Tax=Bacteroidales Re...   143   1e-33
UniRef50_A3MI51 Methylglyoxal synthase n=96 Tax=Bacteria RepID=M...   141   5e-33
UniRef50_B3PXK7 Methylglyoxal synthase n=23 Tax=Bacteria RepID=M...   141   7e-33
UniRef50_O67233 Carbamoyl-phosphate synthase large chain, C-term...   141   7e-33
UniRef50_A7HN41 Methylglyoxal synthase n=1 Tax=Fervidobacterium ...   139   3e-32
UniRef50_C9L646 Methylglyoxal synthase n=12 Tax=Bacteria RepID=C...   138   6e-32
UniRef50_B2A170 Carbamoyl-phosphate synthase large chain n=3 Tax...   136   2e-31
UniRef50_A5FPH5 Methylglyoxal synthase n=5 Tax=Dehalococcoides R...   135   3e-31
UniRef50_Q58776 Carbamoyl-phosphate synthase large chain, C-term...   135   5e-31
UniRef50_A8V5Q7 Carbamoyl-phosphate synthase large subunit (Frag...   135   5e-31
UniRef50_P58761 Methylglyoxal synthase n=6 Tax=Bacteria RepID=MG...   132   3e-30
UniRef50_Q8YQL2 Carbamoyl-phosphate synthase large chain n=44 Ta...   131   5e-30
UniRef50_B0C5A3 Putative uncharacterized protein n=1 Tax=Acaryoc...   131   5e-30
UniRef50_A4J7I4 Methylglyoxal synthase n=1 Tax=Desulfotomaculum ...   131   6e-30
UniRef50_A2BWE6 Carbamoyl-phosphate synthase, large subunit n=56...   130   2e-29
UniRef50_C1MXR9 Predicted protein n=1 Tax=Micromonas pusilla CCM...   128   6e-29
UniRef50_B0U8L9 Carbamoyl-phosphate synthase, large subunit n=3 ...   126   2e-28
UniRef50_Q3APN7 Carbamoyl-phosphate synthase large subunit n=11 ...   126   3e-28
UniRef50_A5FB35 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A5...   125   4e-28
UniRef50_C9KKE3 Carbamoyl-phosphate synthase, large subunit n=1 ...   125   4e-28
UniRef50_Q0FI67 Methylglyoxal synthase n=3 Tax=Rhodobacteraceae ...   124   9e-28
UniRef50_C3XFR9 Carbamoyl-phosphate synthase subunit large n=1 T...   123   2e-27
UniRef50_D1CBW2 Carbamoyl-phosphate synthase, large subunit n=1 ...   123   3e-27
UniRef50_C0A8Y6 Carbamoyl-phosphate synthase, large subunit n=2 ...   122   3e-27
UniRef50_C0R503 Carbamoyl-phosphate synthase large subunit n=6 T...   122   4e-27
UniRef50_A7HVJ4 Carbamoyl-phosphate synthase, large subunit n=20...   121   5e-27
UniRef50_UPI0001B41F6C carbamoyl phosphate synthase large subuni...   121   7e-27
UniRef50_A9QP20 Carbamoyl phosphate synthetase ammonia large cha...   121   9e-27
UniRef50_Q9CKV0 Carbamoyl-phosphate synthase large chain n=6 Tax...   120   1e-26
UniRef50_C9RNJ8 Carbamoyl-phosphate synthase, large subunit n=7 ...   120   2e-26
UniRef50_B5VUE7 Diacylglycerol kinase catalytic region n=2 Tax=A...   118   5e-26
UniRef50_B4SH52 Methylglyoxal synthase-like protein n=2 Tax=cell...   117   1e-25
UniRef50_A2QRW1 Contig An08c0170, complete genome n=337 Tax=cell...   116   2e-25
UniRef50_B1YIR9 Carbamoyl-phosphate synthase large chain n=54 Ta...   116   3e-25
UniRef50_Q9HK17 Carbamoyl-phosphate synthase large chain n=4 Tax...   115   3e-25
UniRef50_O93937 Aspartate carbamoyltransferase n=344 Tax=cellula...   114   7e-25
UniRef50_P07259 Aspartate carbamoyltransferase n=65 Tax=cellular...   114   9e-25
UniRef50_UPI000197805F carbamoyl phosphate synthase large subuni...   114   1e-24
UniRef50_C9LZI0 Carbamoyl-phosphate synthase large subunit chain...   113   1e-24
UniRef50_B2IW98 Forkhead-associated protein n=1 Tax=Nostoc punct...   113   3e-24
UniRef50_B7G8W8 Predicted protein n=7 Tax=cellular organisms Rep...   112   3e-24
UniRef50_D1Y1S0 Carbamoyl-phosphate synthase, large subunit n=2 ...   112   4e-24
UniRef50_B9L7I5 Carbamoyl-phosphate synthase, large subunit n=7 ...   111   7e-24
UniRef50_B7S3K0 Predicted protein n=1 Tax=Phaeodactylum tricornu...   111   8e-24
UniRef50_Q9KHE9 Carbamoyl phosphate synthetase large subunit (Fr...   111   1e-23
UniRef50_Q0TM79 Carbamoyl-phosphate synthase large chain n=94 Ta...   110   1e-23
UniRef50_A6CPS0 Carbamoyl-phosphate synthase large subunit n=2 T...   110   1e-23
UniRef50_Q03WW7 Carbamoyl-phosphate synthase large chain n=115 T...   110   2e-23
UniRef50_Q2FLD9 Carbamoyl-phosphate synthase large chain n=6 Tax...   109   2e-23
UniRef50_O50236 Carbamoyl-phosphate synthase large chain n=3 Tax...   109   2e-23
UniRef50_A9A4K3 Carbamoyl-phosphate synthase, large subunit n=5 ...   109   3e-23
UniRef50_B3LBP4 Carbamoyl phosphate synthetase, putative n=6 Tax...   109   4e-23
UniRef50_Q8IEN3 Carbamoyl phosphate synthetase n=3 Tax=Eukaryota...   108   8e-23
UniRef50_C5JG53 Bifunctional pyrimidine biosynthesis protein pyr...   107   9e-23
UniRef50_B9KXM5 Carbamoyl-phosphate synthase large chain n=794 T...   107   9e-23
UniRef50_C6Q1M4 MGS domain protein n=1 Tax=Clostridium carboxidi...   107   1e-22
UniRef50_Q8UDE9 Carbamoyl-phosphate synthase large chain n=103 T...   107   1e-22
UniRef50_A8F453 Carbamoyl-phosphate synthase large chain n=13 Ta...   106   2e-22
UniRef50_C0NSX2 Carbamoyl-phosphate synthase n=3 Tax=cellular or...   106   2e-22
UniRef50_P31327 Carbamoyl-phosphate synthase [ammonia], mitochon...   106   3e-22
UniRef50_A5D508 Carbamoyl-phosphate synthase large chain n=178 T...   106   3e-22
UniRef50_UPI0001B44E07 carbamoyl phosphate synthase large subuni...   106   3e-22
UniRef50_A3YU56 Methylglyoxal synthase n=2 Tax=Synechococcus Rep...   105   4e-22
UniRef50_Q9ZKT2 Carbamoyl-phosphate synthase large chain n=422 T...   105   4e-22
UniRef50_A6LPD9 Carbamoyl-phosphate synthase large chain n=23 Ta...   105   4e-22
UniRef50_D0J1U7 Methylglyoxal synthase n=3 Tax=Comamonadaceae Re...   104   6e-22
UniRef50_Q17XX3 Carbamoyl-phosphate synthase large chain n=7 Tax...   103   1e-21
UniRef50_B8GEA3 Carbamoyl-phosphate synthase large chain n=2 Tax...   103   1e-21
UniRef50_A0YM60 Putative uncharacterized protein n=1 Tax=Lyngbya...   103   2e-21
UniRef50_C1A4I5 Carbamoyl-phosphate synthase large chain n=223 T...   103   2e-21
UniRef50_C6XKE0 MGS domain protein n=1 Tax=Hirschia baltica ATCC...   101   9e-21
UniRef50_Q05TV7 Methylglyoxal synthase n=1 Tax=Synechococcus sp....   101   9e-21
UniRef50_P05990 Dihydroorotase n=643 Tax=cellular organisms RepI...   101   1e-20
UniRef50_Q1RKZ5 IP15551p (Fragment) n=1 Tax=Drosophila melanogas...    99   2e-20
UniRef50_UPI0001C31DA7 carbamoyl-phosphate synthase, large subun...   100   3e-20
UniRef50_C8PAM0 Carbamoyl-phosphate synthase n=4 Tax=Lactobacill...   100   3e-20
UniRef50_C0AZ23 Putative uncharacterized protein n=1 Tax=Proteus...   100   3e-20
UniRef50_A8JIR0 Carbamoyl phosphate synthase, large subunit n=1 ...   100   3e-20
UniRef50_A9V282 Predicted protein n=2 Tax=cellular organisms Rep...    99   5e-20
UniRef50_D2LJN2 MGS domain protein n=1 Tax=Rhodomicrobium vannie...    98   8e-20
UniRef50_C5KGZ1 Putative uncharacterized protein n=1 Tax=Perkins...    96   4e-19
UniRef50_Q1GA90 Carbamoyl-phosphate synthase, large chain n=28 T...    95   8e-19
UniRef50_B8DTW3 Carbamoyl-phosphate synthase large chain n=400 T...    94   2e-18
UniRef50_A5FYW1 Methylglyoxal synthase-like protein n=4 Tax=Prot...    93   2e-18
UniRef50_B6KSM2 Carbamoyl phosphate synthetase II n=4 Tax=Toxopl...    93   2e-18
UniRef50_A6SWW2 Uncharacterized conserved protein n=12 Tax=cellu...    92   6e-18
UniRef50_C1TLQ6 Carbamoyl-phosphate synthase, large subunit n=1 ...    86   2e-16
UniRef50_UPI00017430FF carbamoyl phosphate synthase large subuni...    80   2e-14
UniRef50_B8BWS2 Predicted protein n=1 Tax=Thalassiosira pseudona...    56   4e-07

Sequences not found previously or not previously below threshold:

UniRef50_UPI000194C4F6 PREDICTED: similar to carbamoylphosphate ...    90   3e-17
UniRef50_Q4SZL4 Chromosome 14 SCAF11586, whole genome shotgun se...    88   6e-17
UniRef50_P27708 Dihydroorotase n=533 Tax=cellular organisms RepI...    81   1e-14
UniRef50_Q4UD12 Carbamoyl phosphate synthase II, putative n=2 Ta...    72   5e-12
UniRef50_B2KDJ0 Carbamoyl-phosphate synthase, large subunit n=10...    71   1e-11
UniRef50_C4QQ90 Aspartate carbamoyltransferase (Carbamoyl-phosph...    68   8e-11
UniRef50_UPI0001BCC751 carbamoyl phosphate synthase large subuni...    67   2e-10
UniRef50_B7PNL6 Carbamoyl-phosphate synthase large chain, putati...    67   2e-10
UniRef50_A7T4N0 Predicted protein (Fragment) n=1 Tax=Nematostell...    63   4e-09
UniRef50_A7ZBN9 Carbamoyl-phosphate synthase, large subunit n=1 ...    62   5e-09
UniRef50_Q1NYU0 Carbamoyl-phosphate synthase large subunit (Frag...    59   4e-08
UniRef50_D2RG70 MGS domain protein n=1 Tax=Archaeoglobus profund...    59   5e-08
UniRef50_A4H8I3 Carbamoyl-phosphate synthase, putative n=17 Tax=...    58   8e-08
UniRef50_B4NUJ8 Rudimentary n=4 Tax=Diptera RepID=B4NUJ8_DROSI         57   1e-07
UniRef50_B4R614 GD17297 n=1 Tax=Drosophila simulans RepID=B4R614...    56   4e-07
UniRef50_Q64E58 Carbamoyl-phosphate synthase large chain n=1 Tax...    54   1e-06
UniRef50_D2MK92 Carbamoyl phosphate synthetase large subunit (Fr...    51   1e-05
UniRef50_C2KIY6 Possible aspartate carbamoyltransferase catalyti...    50   2e-05
UniRef50_D1B6T5 Carbamoyl-phosphate synthase, large subunit n=1 ...    49   5e-05
UniRef50_B6JVJ9 Carbamoyl-phosphate synthase arginine-specific l...    48   9e-05
UniRef50_O28464 Inosine monophosphate cyclohydrolase n=1 Tax=Arc...    46   3e-04
UniRef50_A2BJL3 Carbamoyl-phosphate synthase large chain n=13 Ta...    46   5e-04
UniRef50_B9L973 Bifunctional purine biosynthesis protein PurH n=...    44   0.002
UniRef50_D1B2Y6 Phosphoribosylaminoimidazolecarboxamide formyltr...    43   0.003
UniRef50_A7HM64 IMP cyclohydrolase n=2 Tax=Thermotogaceae RepID=...    43   0.004
UniRef50_A8WNQ4 C. briggsae CBR-PYR-1 protein n=2 Tax=Caenorhabd...    42   0.007
UniRef50_A1VZU4 IMP cyclohydrolase n=25 Tax=Epsilonproteobacteri...    42   0.007
UniRef50_UPI000169A620 carbamoyl-phosphate synthase, large subun...    41   0.010
UniRef50_B9KZE8 Bifunctional purine biosynthesis protein PurH n=...    41   0.010
UniRef50_C5CL84 IMP cyclohydrolase n=10 Tax=Bacteria RepID=PUR9_...    41   0.012
UniRef50_Q27448 Glutamine-dependent carbamoyl phosphate synthase...    41   0.012
UniRef50_B7J5P7 IMP cyclohydrolase n=12 Tax=Bacteria RepID=PUR9_...    41   0.013
UniRef50_O94313 Carbamoyl-phosphate synthase arginine-specific l...    41   0.014
UniRef50_Q9X0X6 IMP cyclohydrolase n=9 Tax=Thermotogaceae RepID=...    41   0.014
UniRef50_B0UWT1 IMP cyclohydrolase n=50 Tax=Gammaproteobacteria ...    41   0.016
UniRef50_Q96CK3 CAD protein (Fragment) n=3 Tax=Euarchontoglires ...    40   0.019
UniRef50_C3KX73 Carbamoyl-phosphate synthase large chain n=1 Tax...    40   0.021
UniRef50_B4EYT2 IMP cyclohydrolase n=36 Tax=Proteobacteria RepID...    39   0.031
UniRef50_D1VVH5 Phosphoribosylaminoimidazolecarboxamide formyltr...    39   0.035
UniRef50_D1JEE9 Putative uncharacterized protein n=1 Tax=uncultu...    39   0.056
UniRef50_UPI0000384730 COG0313: Predicted methyltransferases n=1...    39   0.065

>UniRef50_B7UN42 Methylglyoxal synthase n=174 Tax=Bacteria RepID=MGSA_ECO27
          Length = 152

 Score =  194 bits (494), Expect = 6e-49,   Method: Composition-based stats.
 Identities = 151/152 (99%), Positives = 152/152 (100%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           MELTTRTLP+RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV
Sbjct: 1   MELTTRTLPSRKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
           NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV
Sbjct: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
           ATADFIIQSPHFNDAVDILIPDYQRYLADRLK
Sbjct: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152


>UniRef50_B5XY41 Methylglyoxal synthase n=65 Tax=Gammaproteobacteria
           RepID=MGSA_KLEP3
          Length = 152

 Score =  186 bits (472), Expect = 2e-46,   Method: Composition-based stats.
 Identities = 136/152 (89%), Positives = 142/152 (93%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           MELTTRTL A+KHIALVAHDHCK MLM WV RHQ LL QHVLYATGTTGNL+SRATG+ V
Sbjct: 1   MELTTRTLSAQKHIALVAHDHCKDMLMKWVARHQALLAQHVLYATGTTGNLVSRATGLEV 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
           NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV
Sbjct: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
           +TADFIIQSPHFN  +DILIPDY RYLA+RLK
Sbjct: 121 STADFIIQSPHFNQPLDILIPDYPRYLAERLK 152


>UniRef50_Q4QJW2 Methylglyoxal synthase n=45 Tax=cellular organisms RepID=MGSA_HAEI8
          Length = 152

 Score =  175 bits (445), Expect = 3e-43,   Method: Composition-based stats.
 Identities = 91/151 (60%), Positives = 123/151 (81%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M+ TTRTL   K IALVAHD CK+ L++W ++H+  L+ H+LYATGTTG+++ R TG+++
Sbjct: 1   MQTTTRTLTQHKRIALVAHDSCKKNLLNWTQKHKEALKPHILYATGTTGHILERETGLSI 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
            ++LSGPMGGDQQ+G LI+E KID++IFFWDP+NA PHDPDVKAL+R+ATVWNIPVA N 
Sbjct: 61  QSLLSGPMGGDQQLGGLIAEKKIDMMIFFWDPMNAAPHDPDVKALMRIATVWNIPVAINQ 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRL 151
           ++ADF++ S  F   V+I +PDY+ YL +RL
Sbjct: 121 SSADFLLTSVLFEQDVEIDVPDYEGYLKERL 151


>UniRef50_B8I1E7 Methylglyoxal synthase n=13 Tax=Firmicutes RepID=B8I1E7_CLOCE
          Length = 153

 Score =  173 bits (438), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 68/140 (48%), Positives = 97/140 (69%)

Query: 4   TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
           +   L  +KHIAL+AHD+ K+ L++WV+    +L +H L  TGTT  +I+  TG+ V   
Sbjct: 2   SGNKLGRQKHIALIAHDNRKEDLINWVKSKSDILCRHFLCGTGTTAKMITENTGLPVKKF 61

Query: 64  LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
            SGP+GGDQQ+GA I+ G++D +IFFWD L + PHDPDVKALLR+A +++IPVA N +TA
Sbjct: 62  KSGPLGGDQQIGACIANGEVDFMIFFWDTLTSQPHDPDVKALLRIAVLYDIPVAMNRSTA 121

Query: 124 DFIIQSPHFNDAVDILIPDY 143
           DF++ S    D  +  + DY
Sbjct: 122 DFLLTSSLMEDDYERNVVDY 141


>UniRef50_Q72NU6 Methylglyoxal synthase n=20 Tax=Bacteria RepID=MGSA_LEPIC
          Length = 148

 Score =  170 bits (431), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 74/139 (53%), Positives = 102/139 (73%)

Query: 7   TLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSG 66
           ++PA K I L+AHD+ K+ L++WV+ H+ +L +H LY TGTTG LIS  T + V   LSG
Sbjct: 5   SVPAIKRIVLIAHDNRKEDLVNWVKTHREILSKHQLYGTGTTGKLISEETELPVYRFLSG 64

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GA I+EG +D++IFFWDPL A PHDPDVKALLR+A ++N+P+A N +TAD++
Sbjct: 65  PLGGDQQIGAKIAEGDLDIVIFFWDPLTAQPHDPDVKALLRIAVLYNVPMACNRSTADYM 124

Query: 127 IQSPHFNDAVDILIPDYQR 145
           I SP F      ++  Y  
Sbjct: 125 ISSPQFTKTYKKILLSYNT 143


>UniRef50_B9MRV5 Methylglyoxal synthase n=158 Tax=cellular organisms
           RepID=MGSA_ANATD
          Length = 141

 Score =  170 bits (431), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 68/141 (48%), Positives = 100/141 (70%), Gaps = 2/141 (1%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K++++ +   ++ +L +H LYATGTTG LI  ATG+ V+  L GP+GGD
Sbjct: 1   MNIALIAHDKKKELMVQFAIAYKFILSKHTLYATGTTGRLIQEATGLEVHRFLPGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+G+LI+  +ID++IF  DPL A PH+PDV ALLRL  V NIP+ATN+ATA+ +I++  
Sbjct: 61  QQIGSLIAYNQIDMVIFLRDPLTAQPHEPDVNALLRLCDVHNIPLATNIATAELLIKALD 120

Query: 132 FNDA--VDILIPDYQRYLADR 150
             D    +I+ P  Q+  +D+
Sbjct: 121 RGDLSWREIVNPKLQKNKSDK 141


>UniRef50_Q2SK75 Methylglyoxal synthase n=2 Tax=Gammaproteobacteria RepID=MGSA_HAHCH
          Length = 153

 Score =  170 bits (431), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 78/149 (52%), Positives = 103/149 (69%), Gaps = 1/149 (0%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M            +AL+AHD+ K  L++WVE++   L +  +YATGTTG LI+  TG++V
Sbjct: 1   MTDQVNRPKGVTSVALIAHDNKKADLIAWVEKNSVKLNKCTVYATGTTGKLIAEKTGVDV 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
               SGP+GGDQQ+GALISEGK+D+LIFFWDPL  +PHDPD+KALLRLAT+WN+P A N 
Sbjct: 61  KRCHSGPLGGDQQIGALISEGKVDLLIFFWDPLEPMPHDPDIKALLRLATLWNVPSACNS 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLAD 149
           ATADF++ S  F +      PD+  YL+ 
Sbjct: 121 ATADFLVNSNLF-EEFLPQRPDFDSYLSR 148


>UniRef50_A4BFH8 Methylglyoxal synthase n=1 Tax=Reinekea blandensis MED297
           RepID=A4BFH8_9GAMM
          Length = 147

 Score =  169 bits (429), Expect = 2e-41,   Method: Composition-based stats.
 Identities = 72/142 (50%), Positives = 98/142 (69%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
            +++IALVAHD+ K+ L+ W      L+ +  ++ATGTTG LI  A    VN +LSGP+G
Sbjct: 2   KQRNIALVAHDNKKKELVDWAVAKAELMAEIGIFATGTTGRLIEDAMKRPVNRLLSGPLG 61

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GDQQ+GA I+EG+ID+LIFFWDPL   PHDPD+KALLR+A ++NIPVA N A+AD++I S
Sbjct: 62  GDQQIGAKIAEGEIDLLIFFWDPLEPQPHDPDIKALLRIAALYNIPVACNKASADYMIHS 121

Query: 130 PHFNDAVDILIPDYQRYLADRL 151
           P  +       PD+  Y   + 
Sbjct: 122 PLLHGDYVPDEPDFSDYTLRKT 143


>UniRef50_A9KFK7 Methylglyoxal synthase n=6 Tax=Coxiella burnetii RepID=MGSA_COXBN
          Length = 143

 Score =  169 bits (428), Expect = 3e-41,   Method: Composition-based stats.
 Identities = 75/138 (54%), Positives = 97/138 (70%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           K IALVAHD  K+ L+ W+++HQ LL+ H LYATG+TG  I +   + V  M SGP+GGD
Sbjct: 4   KKIALVAHDRMKKELIEWIKKHQNLLKHHELYATGSTGQAIEKTLNVTVTKMESGPLGGD 63

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
            Q+GA I   +ID+LIFFWDPL A PHDPDV+ALLR+A VWN+PVA N +TAD+++ SP 
Sbjct: 64  LQLGAKIVNKEIDILIFFWDPLEAQPHDPDVRALLRIAVVWNLPVACNASTADYLLTSPL 123

Query: 132 FNDAVDILIPDYQRYLAD 149
           F+       PDY+ Y   
Sbjct: 124 FDSDYHPETPDYEAYRNR 141


>UniRef50_UPI0001745D5F methylglyoxal synthase n=1 Tax=Verrucomicrobium spinosum DSM 4136
           RepID=UPI0001745D5F
          Length = 154

 Score =  166 bits (422), Expect = 1e-40,   Method: Composition-based stats.
 Identities = 72/138 (52%), Positives = 95/138 (68%), Gaps = 1/138 (0%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
            I LVAHDHCK  L++W ++H+  L+   L ATGTTG+L+ +  G+ V   LSGP+GGD 
Sbjct: 3   TIGLVAHDHCKDNLLAWAQKHREQLQGWTLCATGTTGSLLEKELGLPVRRFLSGPLGGDL 62

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           Q+G  I+EG++D+LIFFWDPL+A PHDPDVKALLR+A +WN+PVA N A AD ++     
Sbjct: 63  QIGTEIAEGRMDLLIFFWDPLSAQPHDPDVKALLRVAVLWNVPVAMNEAGADLLLIGLAQ 122

Query: 133 NDAVDILIPDYQRYLADR 150
                  IPD+  Y A R
Sbjct: 123 G-TYQRFIPDHTNYRAVR 139


>UniRef50_Q1QX97 Methylglyoxal synthase n=4 Tax=Bacteria RepID=Q1QX97_CHRSD
          Length = 159

 Score =  165 bits (418), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 81/147 (55%), Positives = 106/147 (72%)

Query: 4   TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            TRTLPARK IAL+AHD  K  L++W ER +  L +H L  TGTT   ++   G+ V+ +
Sbjct: 10  ATRTLPARKRIALIAHDGKKAELLAWAERWRDTLARHDLVGTGTTAQRVAETLGLEVHGL 69

Query: 64  LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
           +SGP+GGDQQ+GA I+E ++D+L+FFWDP   +PHDPDVKALLRLA +WN+PVATN A+A
Sbjct: 70  MSGPLGGDQQIGARITESRLDMLVFFWDPFAPMPHDPDVKALLRLAALWNLPVATNAASA 129

Query: 124 DFIIQSPHFNDAVDILIPDYQRYLADR 150
           DFII SP     V + +PD   +LA R
Sbjct: 130 DFIITSPLVAQEVTVNVPDANDWLATR 156


>UniRef50_A0LVE0 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A0LVE0_ACIC1
          Length = 167

 Score =  165 bits (418), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 73/145 (50%), Positives = 96/145 (66%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M     T   R+HIALVAHD+ K+ L+ W   ++  L QH LYATGTTG L+     + +
Sbjct: 1   MTTQALTGTPRRHIALVAHDNKKRELLEWAAYNRATLAQHELYATGTTGALLREQLDLEI 60

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +LSGP+GGD Q+GA I+ G +D+L+FFWDPL   PHDPDVKALLR+A +WNI +A N 
Sbjct: 61  RCLLSGPLGGDLQIGAQIAAGSVDLLVFFWDPLEPQPHDPDVKALLRVAVLWNIAIACNR 120

Query: 121 ATADFIIQSPHFNDAVDILIPDYQR 145
            TAD +I SP F+    I  P Y++
Sbjct: 121 TTADMVISSPLFSGPYQIHRPTYRQ 145


>UniRef50_B0KAD1 Methylglyoxal synthase n=27 Tax=cellular organisms RepID=MGSA_THEP3
          Length = 132

 Score =  164 bits (415), Expect = 9e-40,   Method: Composition-based stats.
 Identities = 62/131 (47%), Positives = 93/131 (70%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K++++++   ++ + E+  +YATG TG LI  ATG+NVN +L GP+GGD
Sbjct: 1   MNIALIAHDQKKELMVNFAIAYKHIFEKCNIYATGHTGQLIKEATGLNVNCLLPGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA+I+E KID++IF  DPL A PH+PD+ ALLR+  V +IP+ATN+ATA+ +++   
Sbjct: 61  QQIGAMIAENKIDMVIFLRDPLTAQPHEPDILALLRVCDVHSIPLATNIATAEVLLKGME 120

Query: 132 FNDAVDILIPD 142
                   I D
Sbjct: 121 QGLLEWREIED 131


>UniRef50_C6BZQ4 Methylglyoxal synthase n=7 Tax=Bacteria RepID=MGSA_DESAD
          Length = 157

 Score =  161 bits (408), Expect = 7e-39,   Method: Composition-based stats.
 Identities = 77/157 (49%), Positives = 102/157 (64%), Gaps = 13/157 (8%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT----------G 57
           +   K+IA+VAHD+CK+ L+ +V+ +  +L +H L ATGTTG L+ +            G
Sbjct: 1   MSKVKNIAVVAHDNCKKELLDFVDCNHNILSRHNLVATGTTGGLVEKMIMERVEQKADEG 60

Query: 58  M---NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNI 114
                VN M SGP+GGDQQ+GA+ISEGKIDVLIFFWDP+   PHD DVKALLRLA ++NI
Sbjct: 61  YEFKPVNRMKSGPLGGDQQLGAMISEGKIDVLIFFWDPMQPQPHDVDVKALLRLAVLYNI 120

Query: 115 PVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRL 151
           P A+N +TA+F+I SP F         D+  Y   +L
Sbjct: 121 PTASNRSTAEFLISSPFFEGEFQRKETDFSSYTQRKL 157


>UniRef50_A4IQ66 Methylglyoxal synthase n=37 Tax=Bacteria RepID=MGSA_GEOTN
          Length = 144

 Score =  160 bits (404), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 58/123 (47%), Positives = 85/123 (69%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
             IAL+AHD  K  ++++   + P+L  H LYATGTTG  I  ATG+ V+   SGP GGD
Sbjct: 1   MKIALIAHDEKKAEMVAFATAYAPVLANHELYATGTTGLRIQEATGLAVHRFQSGPYGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           Q++GA+I+  ++D++IFF DPL A PH+PD+ AL+RL  V+ +P+ATN+ TA+ +I+   
Sbjct: 61  QEIGAMIARNEMDLVIFFRDPLTAQPHEPDISALMRLCDVYAVPLATNIGTAELLIRGLE 120

Query: 132 FND 134
             D
Sbjct: 121 RGD 123


>UniRef50_C9KKW1 Methylglyoxal synthase n=1 Tax=Mitsuokella multacida DSM 20544
           RepID=C9KKW1_9FIRM
          Length = 132

 Score =  154 bits (389), Expect = 1e-36,   Method: Composition-based stats.
 Identities = 54/130 (41%), Positives = 82/130 (63%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGG 70
            K IAL+AHD  K  ++ +V  H+  L +  L AT TTG LI+   G+ V  MLSGP+GG
Sbjct: 1   MKTIALIAHDKKKSEMLEFVGHHKDFLAKFHLIATRTTGTLINDTFGLGVETMLSGPLGG 60

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
           DQQ+GA ++ G++D ++F  DPL + PH+PD+ ALLRL  V ++P+ATN  +A  ++   
Sbjct: 61  DQQIGARVAVGEVDYVVFLRDPLTSQPHEPDINALLRLCDVHDVPLATNRKSAHILLAYA 120

Query: 131 HFNDAVDILI 140
             ++  +   
Sbjct: 121 AAHEGDEPAE 130


>UniRef50_C1TMX7 Methylglyoxal synthase n=1 Tax=Dethiosulfovibrio peptidovorans DSM
           11002 RepID=C1TMX7_9BACT
          Length = 157

 Score =  152 bits (385), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 66/143 (46%), Positives = 96/143 (67%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
           + A K IALVAHD  K+ L+ W +RH+  L  H L +TGTTG L+  A G+ ++ + SGP
Sbjct: 1   MEAVKKIALVAHDSRKKDLIRWAKRHREQLAAHRLCSTGTTGALLEAALGLPIDKLKSGP 60

Query: 68  MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
           +GGDQQ+GA I+  ++D ++F WDPLN   HD D+KALLR+AT++NIP+A N+A+ADF+ 
Sbjct: 61  LGGDQQLGARIACERLDAIVFLWDPLNTQAHDSDIKALLRIATLYNIPMACNMASADFLF 120

Query: 128 QSPHFNDAVDILIPDYQRYLADR 150
            SP  +   +    D+  +   R
Sbjct: 121 SSPLISLPYNNEHRDFDAHQQAR 143


>UniRef50_D0MG34 Methylglyoxal synthase n=1 Tax=Rhodothermus marinus DSM 4252
           RepID=D0MG34_RHOM4
          Length = 140

 Score =  152 bits (385), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 54/118 (45%), Positives = 76/118 (64%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
           + IAL+AHD  K  ++++  +H+ LL +  L  TGTTG L+    G+ V   LSGP+GGD
Sbjct: 6   RTIALIAHDGKKADMVAFAMQHRDLLARFELVGTGTTGKLLEEKVGLRVRRFLSGPLGGD 65

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
            Q+ A +  G I  + FF DPL+  PHDPD++ LLR   V N+P+ATN ATA +I+ S
Sbjct: 66  VQIAARVVTGDIHAVFFFVDPLDKHPHDPDIQTLLRACNVHNVPLATNPATAHYILTS 123


>UniRef50_B1YKL9 Methylglyoxal synthase n=78 Tax=Bacteria RepID=MGSA_EXIS2
          Length = 144

 Score =  152 bits (384), Expect = 4e-36,   Method: Composition-based stats.
 Identities = 56/123 (45%), Positives = 84/123 (68%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +IAL+AHD  K  +M +   ++    ++ LYATGTTG  I  AT + V+   SGP+GGD
Sbjct: 1   MNIALIAHDEKKDEMMMFTRAYEAYFAKNTLYATGTTGQRIMEATALTVHRCKSGPLGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           Q++GA+++ G+ID++IF  DPL A PH+PDV AL+RL  V+++P+ATNV TA+ +I    
Sbjct: 61  QEIGAMVARGEIDIVIFLRDPLTAQPHEPDVSALIRLCDVYDLPLATNVGTAEILINGLE 120

Query: 132 FND 134
             +
Sbjct: 121 QGE 123


>UniRef50_C2HDU2 Methylglyoxal synthase n=12 Tax=Enterococcus faecium
           RepID=C2HDU2_ENTFC
          Length = 150

 Score =  150 bits (380), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 59/122 (48%), Positives = 88/122 (72%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
             IAL+AHD  K M++     ++ +LE+H L+ATGTTG  I+ ATG+ ++   SGP+GGD
Sbjct: 11  MKIALIAHDRKKSMMVKLATAYKTILEKHELFATGTTGQRITEATGLPIHRFKSGPLGGD 70

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA+ISE ++D++IF  DPL A PH+PDV AL+RL+ V+ IP+ATN+ TA+ +++   
Sbjct: 71  QQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYEIPLATNIGTAEVLLRGLE 130

Query: 132 FN 133
             
Sbjct: 131 AG 132


>UniRef50_Q10YJ6 Cyclic nucleotide-binding protein n=2 Tax=Bacteria
           RepID=Q10YJ6_TRIEI
          Length = 322

 Score =  150 bits (379), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 53/150 (35%), Positives = 91/150 (60%), Gaps = 3/150 (2%)

Query: 6   RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA-ML 64
            ++ + K++AL+AH+  K  L+ +V+ H  L+ +  L ATGTTG L+ +ATG+ ++  + 
Sbjct: 147 FSVDSTKYLALIAHNEMKSSLVEFVKEHIKLITKFPLVATGTTGLLLHQATGVVLSRKVK 206

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
           SGP+GGDQ +G++IS   I  ++FF DPL++ PH  D++AL RL  V+ +P+ATN +TA 
Sbjct: 207 SGPLGGDQAIGSMISTDNICGVLFFRDPLSSHPHHADIEALSRLCDVYQVPLATNPSTAK 266

Query: 125 FIIQSPHFN--DAVDILIPDYQRYLADRLK 152
            I+        +          +Y  ++ +
Sbjct: 267 AILLYLDNTPLEGKHNFSLALTKYQENQSR 296


>UniRef50_Q3AGN5 Cyclic nucleotide-binding domain (CNMP-BD) protein n=1
           Tax=Synechococcus sp. CC9605 RepID=Q3AGN5_SYNSC
          Length = 297

 Score =  150 bits (379), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 58/153 (37%), Positives = 85/153 (55%), Gaps = 3/153 (1%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMN-VN 61
                   RK++AL+AH++ K+ LM +   H   LE+  L ATGTTG+++ + TG+    
Sbjct: 140 AAENYTDTRKYLALIAHNNMKESLMEFCGMHSRKLEKFPLMATGTTGSMLYKKTGLVLSK 199

Query: 62  AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            + SGP+GGDQ VG LIS   I  +IFF DPL+  PH  D++AL RL  V+ +P ATN  
Sbjct: 200 KVASGPLGGDQAVGTLISTRNIIGVIFFRDPLSPHPHHADIEALGRLCDVYQVPFATNPQ 259

Query: 122 TADFIIQSPHFNDAVDILIP--DYQRYLADRLK 152
           + + I+       +    IP    Q Y+  + K
Sbjct: 260 SGEAILDYLLSGKSERESIPNHVLQTYIQGQTK 292


>UniRef50_Q72HP3 Methylglyoxal synthase n=3 Tax=Bacteria RepID=MGSA_THET2
          Length = 126

 Score =  148 bits (375), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 55/126 (43%), Positives = 83/126 (65%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGG 70
            K +AL+AHD  K  ++++  RH+ +L ++ L ATGTTG  I  ATG+ V  +LSGP+GG
Sbjct: 1   MKALALIAHDAKKDEMVAFCLRHKDVLARYPLLATGTTGARIQEATGLAVERVLSGPLGG 60

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
           D Q+GA ++EGK+  ++F  DPL A PH+PDV+AL+R+  V  +P+ATN+  A+ +I   
Sbjct: 61  DLQIGARVAEGKVLAVVFLQDPLTAKPHEPDVQALMRVCNVHGVPLATNLVAAEALIAWI 120

Query: 131 HFNDAV 136
                 
Sbjct: 121 RKGTPQ 126


>UniRef50_Q8UIV6 Methylglyoxal synthase n=8 Tax=Alphaproteobacteria RepID=MGSA_AGRT5
          Length = 127

 Score =  148 bits (375), Expect = 4e-35,   Method: Composition-based stats.
 Identities = 61/122 (50%), Positives = 85/122 (69%), Gaps = 1/122 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAMLSG 66
           +  ++ IAL+AHD  K  +  +   HQ +L    + ATGTTG  +  A  G+ V  + SG
Sbjct: 1   MEGQRCIALIAHDEKKDDMADFARHHQKVLASFRIVATGTTGGRVQEACPGLEVIRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GA+I+ G++D+LIFF DPL A+PHD DVKAL RLATV++IP+A N ATA+ +
Sbjct: 61  PLGGDQQIGAMIATGEVDMLIFFTDPLTAMPHDVDVKALTRLATVYDIPMALNRATAENL 120

Query: 127 IQ 128
           I 
Sbjct: 121 ID 122


>UniRef50_Q55452 Uncharacterized protein sll0036 n=7 Tax=Bacteria RepID=Y036_SYNY3
          Length = 433

 Score =  147 bits (372), Expect = 9e-35,   Method: Composition-based stats.
 Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 1/139 (0%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
           HIAL+AHD+ K  L+++V++H+ L  ++ L ATG TG L+   TG+ V+ + SGP+GGD 
Sbjct: 4   HIALIAHDNKKDALVNFVQQHKSLFSRYDLIATGQTGELVRNKTGLAVDTVFSGPLGGDT 63

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           Q+   I +G I  +IF  DPL A PH+PD++ LLRL  V+N+P+A N+ATA  +I+    
Sbjct: 64  QIATQIIDGTIAAVIFLIDPLYAQPHEPDIRTLLRLCEVYNVPLAINLATAKAVIKLLGK 123

Query: 133 ND-AVDILIPDYQRYLADR 150
                 I  P   +   +R
Sbjct: 124 TKTGHLIFNPVAGQGNVER 142


>UniRef50_D2BG68 Methylglyoxal synthase n=5 Tax=Dehalococcoides RepID=D2BG68_DEHSV
          Length = 144

 Score =  146 bits (368), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 56/132 (42%), Positives = 85/132 (64%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
            R  +ALVAHD+ KQ ++  V++H+  L    L AT TTG LI  +T +NVN + SGP+G
Sbjct: 2   ERITLALVAHDNKKQEMVELVKKHETDLGSLNLVATRTTGKLIQASTSLNVNLLQSGPLG 61

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GDQQ+GA+++ G +  +IF  DPL A PH+PD+ AL+R+  V N+P+ATN++TA+ ++  
Sbjct: 62  GDQQIGAMVASGVVTAIIFLRDPLTAQPHEPDISALMRVCDVHNVPLATNISTAEAVLHL 121

Query: 130 PHFNDAVDILIP 141
              +        
Sbjct: 122 IFEHPEELKEHR 133


>UniRef50_UPI0000E11027 methylglyoxal synthase n=1 Tax=Rhodobacterales bacterium HTCC2255
           RepID=UPI0000E11027
          Length = 151

 Score =  145 bits (366), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 66/140 (47%), Positives = 90/140 (64%), Gaps = 2/140 (1%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISR-ATGMNVNAMLSGPMG 69
            K IA+VAHD  K   + W + H   L  H ++ATGTTG LI      +++ A+ SGP+G
Sbjct: 8   TKRIAIVAHDKMKPQAIEWTKTHASKLNSHQIFATGTTGKLIQAANPNLSIKALKSGPLG 67

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GDQQ+GA+I EG++D+L FF DP+   PHD D+KALLRL+T++N  VA N+ATADF+I+S
Sbjct: 68  GDQQLGAMICEGQLDILFFFTDPMTPQPHDVDIKALLRLSTMYNCVVACNIATADFVIES 127

Query: 130 PHFNDAVDILIPDYQRYLAD 149
           P F         D+  Y   
Sbjct: 128 PLFVLP-QTHTSDFSDYSER 146


>UniRef50_C4ZA41 Methylglyoxal synthase n=10 Tax=Firmicutes RepID=C4ZA41_EUBR3
          Length = 131

 Score =  144 bits (364), Expect = 7e-34,   Method: Composition-based stats.
 Identities = 52/123 (42%), Positives = 80/123 (65%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            +I LVAHD  K+++ ++   ++ +L ++ LYATGTTG LI     ++V+  L+G +GG 
Sbjct: 1   MNIGLVAHDSKKKLMQNFCIAYRGILSKNNLYATGTTGRLIEEVANLSVHKYLAGHLGGI 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           QQ+GA I    ID++IF  DPL   PH+P+V ++ R+    NIP+ATN+ATA+ +I S  
Sbjct: 61  QQLGAQIEHNDIDLVIFLRDPLKPKPHEPEVNSIFRICDEHNIPLATNLATAELLILSLD 120

Query: 132 FND 134
             D
Sbjct: 121 RGD 123


>UniRef50_Q2RSM7 Methylglyoxal synthase n=1 Tax=Rhodospirillum rubrum ATCC 11170
           RepID=Q2RSM7_RHORT
          Length = 155

 Score =  144 bits (363), Expect = 9e-34,   Method: Composition-based stats.
 Identities = 65/149 (43%), Positives = 84/149 (56%), Gaps = 5/149 (3%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISR-ATGMNVNAMLSG 66
            P R  I LVAHD  K+ +  WV  +  +L  H L ATGTT  ++       ++  + SG
Sbjct: 7   TPPRMTIGLVAHDGQKRAMGQWVAANATVLGHHALVATGTTARVLKEQNPTFDITGLKSG 66

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P GGDQQ+GALI+EG +D LIFF DP+   PHD DVKAL+RLA V  IP A N ATAD +
Sbjct: 67  PFGGDQQLGALIAEGHLDCLIFFVDPMEPQPHDVDVKALIRLAQVHEIPAACNRATADLM 126

Query: 127 IQSPHFN----DAVDILIPDYQRYLADRL 151
           I SP F      +       +  Y   ++
Sbjct: 127 ITSPLFGVLRAGSFPPAEERFAVYANRKV 155


>UniRef50_C3MBY3 Methylglyoxal synthase n=5 Tax=Alphaproteobacteria RepID=MGSA_RHISN
          Length = 126

 Score =  144 bits (363), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 62/122 (50%), Positives = 85/122 (69%), Gaps = 1/122 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNAMLSG 66
           +  RK +AL+AHD  K  L ++ + H+  L    + ATGTTG  +  A  G++V  + SG
Sbjct: 1   MADRKCLALIAHDQKKNDLAAFAKAHEATLSGWKIVATGTTGGRVLDACPGLDVTRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GALI+ G +D LIFF DPL A+PHD DVKAL+RLA V++IP+A N ATA+ +
Sbjct: 61  PLGGDQQIGALIATGDVDCLIFFVDPLTAMPHDVDVKALMRLAIVYDIPMALNRATAEQL 120

Query: 127 IQ 128
           I 
Sbjct: 121 ID 122


>UniRef50_A6L618 Methylglyoxal synthase n=34 Tax=Bacteroidales RepID=A6L618_BACV8
          Length = 178

 Score =  143 bits (362), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 67/146 (45%), Positives = 84/146 (57%), Gaps = 8/146 (5%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-------GMNVNAML 64
           + I LVAHD  K+ ++ WV  +   L  H  Y TGTTG LI +A          ++  + 
Sbjct: 6   RRIGLVAHDAMKKDMIEWVLWNSERLIGHKFYCTGTTGTLIKKALEEKHPEIKWDITILK 65

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
           SGP+GGDQQ+G+ I EG+ID L FF DP+   PHD DVKAL RLA V NI    N +TAD
Sbjct: 66  SGPLGGDQQIGSRIVEGEIDYLFFFTDPMTLQPHDTDVKALTRLAGVENIVFCCNRSTAD 125

Query: 125 FIIQSPHFNDA-VDILIPDYQRYLAD 149
            II SP F D   + + PDY  Y   
Sbjct: 126 HIITSPLFTDPTYERIHPDYTNYTQR 151


>UniRef50_A3MI51 Methylglyoxal synthase n=96 Tax=Bacteria RepID=MGSA_BURM7
          Length = 130

 Score =  141 bits (357), Expect = 5e-33,   Method: Composition-based stats.
 Identities = 55/121 (45%), Positives = 81/121 (66%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
            IAL+AHD  K  +++    ++  L Q  L ATGTTG  I++A G++V   LSGP+GGD 
Sbjct: 5   RIALIAHDAKKDDIVALAGAYRATLAQCRLVATGTTGGRIAQAHGLDVERKLSGPLGGDL 64

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           Q+GA +++G++D++IF  DP+ A PHDPD+ AL+R   V ++PVATNVATA  ++     
Sbjct: 65  QIGAELADGRVDIVIFLRDPMTAQPHDPDITALVRACDVHDVPVATNVATARVLLDDLAR 124

Query: 133 N 133
            
Sbjct: 125 R 125


>UniRef50_B3PXK7 Methylglyoxal synthase n=23 Tax=Bacteria RepID=MGSA_RHIE6
          Length = 126

 Score =  141 bits (356), Expect = 7e-33,   Method: Composition-based stats.
 Identities = 58/126 (46%), Positives = 85/126 (67%), Gaps = 1/126 (0%)

Query: 8   LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTG-NLISRATGMNVNAMLSG 66
           +   K +AL+AHD  K  + ++   ++ LL +  + ATGTTG  ++  A  ++V  + SG
Sbjct: 1   MAGGKCLALIAHDQKKDDMAAFARANRDLLSRWKIVATGTTGGRVLDAAPDLDVTRLKSG 60

Query: 67  PMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFI 126
           P+GGDQQ+GALIS G++D LIFF DPL  +PHD DVKAL+RLA V++IP+A N ATA  +
Sbjct: 61  PLGGDQQIGALISTGEVDALIFFVDPLTPMPHDVDVKALMRLAIVYDIPMALNHATAIKL 120

Query: 127 IQSPHF 132
           + +   
Sbjct: 121 LPTLEA 126


>UniRef50_O67233 Carbamoyl-phosphate synthase large chain, C-terminal section n=28
           Tax=Bacteria RepID=CARB2_AQUAE
          Length = 537

 Score =  141 bits (356), Expect = 7e-33,   Method: Composition-based stats.
 Identities = 24/149 (16%), Positives = 52/149 (34%), Gaps = 12/149 (8%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                 LP + ++ +   D  K  ++   +  + L     +YAT  T   +    G+N  
Sbjct: 392 LSAGYRLPEKGNLFISVADRDKPKILELAKEFEKL--GFGIYATSGTYKFLKEH-GVNAK 448

Query: 62  AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            +L    G    V  +I  G+I ++I   +  +      D   + R    +N+P  T + 
Sbjct: 449 RVLKVSEG-RPNVVDMIINGEIHLVI---NTPSGKREKSDAYYIRRACVQFNVPYYTTMR 504

Query: 122 TADFIIQSPHFND-----AVDILIPDYQR 145
               ++++             + +   Q 
Sbjct: 505 AGYAVLEAIKSIKKLKEEGKGLSVHSLQE 533


>UniRef50_A7HN41 Methylglyoxal synthase n=1 Tax=Fervidobacterium nodosum Rt17-B1
           RepID=A7HN41_FERNB
          Length = 119

 Score =  139 bits (350), Expect = 3e-32,   Method: Composition-based stats.
 Identities = 48/105 (45%), Positives = 69/105 (65%)

Query: 29  WVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIF 88
           +V+  + + E+  LYAT +TG +I    G+ VN   SGP GGD Q+G++I  G+ID +IF
Sbjct: 2   FVKEWKNVFERCELYATKSTGKIIEEKIGLKVNKFESGPYGGDLQIGSMIVNGEIDFVIF 61

Query: 89  FWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFN 133
             DPL A PH+PDV ALLR+  V N+P+ATN+ATA+ ++      
Sbjct: 62  LRDPLTAQPHEPDVSALLRVCDVHNVPLATNLATAEALVLEIQKK 106


>UniRef50_C9L646 Methylglyoxal synthase n=12 Tax=Bacteria RepID=C9L646_RUMHA
          Length = 130

 Score =  138 bits (348), Expect = 6e-32,   Method: Composition-based stats.
 Identities = 45/130 (34%), Positives = 73/130 (56%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
            ++ ++AH+  K ++  +   ++ +L +H +YATGTTG  I   T + V+  L G MGGD
Sbjct: 1   MNVGIIAHNSKKALIEDFCIAYKNILAKHEIYATGTTGRRIEEVTNLRVHKFLPGSMGGD 60

Query: 72  QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           +Q   +I  G ID++IFF++P      +PDV  +      +NIP+ATN+ATA+ +I    
Sbjct: 61  KQFTEMIERGDIDMVIFFYNPAMIDGTEPDVYQISGCCDQYNIPIATNIATAESLILGLE 120

Query: 132 FNDAVDILIP 141
             D    L  
Sbjct: 121 QGDLDYRLNR 130


>UniRef50_B2A170 Carbamoyl-phosphate synthase large chain n=3 Tax=Bacteria
            RepID=CARB_NATTJ
          Length = 1106

 Score =  136 bits (344), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 31/150 (20%), Positives = 58/150 (38%), Gaps = 7/150 (4%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  +  ++     + +   D  K+ +   VER Q L     ++AT  T   + R  G++V
Sbjct: 960  MLASGFSINLNGGVLVTVADRDKEAVRPLVERFQKL--GLKIFATSGTAEFL-RNQGIDV 1016

Query: 61   NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
              +    +     +  LI EG+I+ +I  +          D   + R A    IP  T++
Sbjct: 1017 EQVPKI-VDESPNIIDLIREGQINYVINTFT--IGKEPARDGFKIRRAAVENGIPCLTSL 1073

Query: 121  ATADFIIQSPHFN-DAVDILIPDYQRYLAD 149
             TA  ++ +           +   Q YL +
Sbjct: 1074 DTASALLTAMESLDRGESKQVKSLQDYLKE 1103


>UniRef50_A5FPH5 Methylglyoxal synthase n=5 Tax=Dehalococcoides RepID=A5FPH5_DEHSB
          Length = 143

 Score =  135 bits (341), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 49/133 (36%), Positives = 75/133 (56%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
            +  + L+AHD+CK+ ++  +  +  L++ H L AT +TG LI + TG+ V    SGP G
Sbjct: 4   PKITLGLIAHDNCKKDMVQLIHSYAHLMKGHHLIATRSTGELIQKHTGLPVILKESGPDG 63

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           G+ Q+G  ++   I  +IF  DPL    H+PDV AL+R+    NIP+ATN ATA  ++  
Sbjct: 64  GELQLGGFVASRIIKAVIFLRDPLKRKSHEPDVTALMRICDAHNIPLATNRATAACVLHM 123

Query: 130 PHFNDAVDILIPD 142
             F+       P 
Sbjct: 124 ALFHPEKLDDTPP 136


>UniRef50_Q58776 Carbamoyl-phosphate synthase large chain, C-terminal section n=10
           Tax=cellular organisms RepID=CARB2_METJA
          Length = 618

 Score =  135 bits (340), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 22/148 (14%), Positives = 52/148 (35%), Gaps = 6/148 (4%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                 LP   ++ +   D  K+ ++   ++   L     +YAT  T  ++    G+   
Sbjct: 472 LSANMELPIVGNVFISVRDRDKKHIVDVAKKLHEL--GFTIYATEGTAKVLREN-GIPAI 528

Query: 62  AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            +       +  +  L+ +GK+ ++I   +  +      D   + R A    IP  T + 
Sbjct: 529 LVKKISESPNDNILKLMRDGKMHLII---NTSSGKKAKSDGYYIRRAAVDLGIPYITTIP 585

Query: 122 TADFIIQSPHFNDAVDILIPDYQRYLAD 149
            A   +++       ++ +       A 
Sbjct: 586 GAKAAVKAIEAVKTGELSVYSLDELDAR 613


>UniRef50_A8V5Q7 Carbamoyl-phosphate synthase large subunit (Fragment) n=1
           Tax=Hydrogenivirga sp. 128-5-R1-1 RepID=A8V5Q7_9AQUI
          Length = 289

 Score =  135 bits (340), Expect = 5e-31,   Method: Composition-based stats.
 Identities = 20/143 (13%), Positives = 46/143 (32%), Gaps = 7/143 (4%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
            T   LP   ++ +   D  K  ++   ++ + L    ++ AT  T   ++    +    
Sbjct: 148 ATGLLLPESGNVFISVADKDKPAVLEIAKKLKSL--GFIILATKGTFKFLTEN-NVEAQL 204

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
           +          +   I  G++ ++I   +  +      D   + R A    +P  T +  
Sbjct: 205 VSKLSE-ERPNIVDKIRNGEVQLII---NTPSGKRERSDAYYIRRAAVEHKVPYFTTIRG 260

Query: 123 ADFIIQSPHFNDAVDILIPDYQR 145
           A     +        I +   Q 
Sbjct: 261 AYAAAVAIQCYKEKGIDVKPIQE 283


>UniRef50_P58761 Methylglyoxal synthase n=6 Tax=Bacteria RepID=MGSA_TRESO
          Length = 158

 Score =  132 bits (332), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 55/142 (38%), Positives = 81/142 (57%), Gaps = 6/142 (4%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT---GM--NVNAMLSGP 67
            IALVAHD+ K  ++ W   +  +L QH L+ TGTTG L+  +    G+  ++  M SGP
Sbjct: 6   RIALVAHDNRKADIVDWALNNAEMLSQHRLFGTGTTGTLVRESFMKRGIASDITCMHSGP 65

Query: 68  MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
           MGGD ++ AL+   +ID  +FF D LN  PH+ D++ LLR   + NIP+A N  +AD +I
Sbjct: 66  MGGDAEIAALVVRKEIDFAVFFIDDLNPQPHEADIQMLLRQCRIHNIPIACNRYSADLMI 125

Query: 128 QSPHFND-AVDILIPDYQRYLA 148
            S  ++D       P Y  +  
Sbjct: 126 TSSLWDDAGYVPKDPIYAPFDR 147


>UniRef50_Q8YQL2 Carbamoyl-phosphate synthase large chain n=44 Tax=cellular organisms
            RepID=CARB_ANASP
          Length = 1104

 Score =  131 bits (331), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 28/148 (18%), Positives = 50/148 (33%), Gaps = 7/148 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP    + +   D  K   +  V     L     + AT  T  ++    G+NV 
Sbjct: 963  LGAGERLPLTGTVFVSMSDRDKSAAVPVVREFIDL--GFKVMATFGTRRVLLEN-GLNVE 1019

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +L    G    V   I   KI ++I   +  +      D + + R    + IP+ T +A
Sbjct: 1020 LVLKLHEG-RPHVIDAIKNQKIQLII---NTPSGEEAQTDARLIRRTGLAYKIPIITTIA 1075

Query: 122  TADFIIQSPHFNDAVDILIPDYQRYLAD 149
             A   + +        + +   Q Y  +
Sbjct: 1076 GAKATVAAIRSMQNTTLDVKTIQEYCPN 1103


>UniRef50_B0C5A3 Putative uncharacterized protein n=1 Tax=Acaryochloris marina
           MBIC11017 RepID=B0C5A3_ACAM1
          Length = 430

 Score =  131 bits (331), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 49/141 (34%), Positives = 77/141 (54%), Gaps = 1/141 (0%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGG 70
              IAL+AH+  K  +++ V+R+  LL ++++ AT  TG  I  AT + V  ++S   GG
Sbjct: 2   PNSIALIAHESKKNDIVTLVQRYHSLLNRYLIVATPDTGKWIQDATNLTVETVVSEADGG 61

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
             Q+ A +   ++  +IF  D +N     PDV+ALLR+   + +P+ATN+ATA+  IQ  
Sbjct: 62  LLQIAARLVSSEVVGVIFLMDTINVPSQLPDVQALLRVCNRYEVPLATNIATAELAIQGV 121

Query: 131 -HFNDAVDILIPDYQRYLADR 150
               DA  I  P   +   DR
Sbjct: 122 AKRRDAYLIFNPIAGQGNPDR 142


>UniRef50_A4J7I4 Methylglyoxal synthase n=1 Tax=Desulfotomaculum reducens MI-1
           RepID=A4J7I4_DESRM
          Length = 139

 Score =  131 bits (330), Expect = 6e-30,   Method: Composition-based stats.
 Identities = 47/110 (42%), Positives = 71/110 (64%)

Query: 23  KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGK 82
           K    +  +  Q  L QH L  TGTTG+LI    G++V   +SGP+GGDQQ+G  I++G+
Sbjct: 30  KNSENALDKEFQLQLSQHDLIGTGTTGSLIKEKVGLDVTCYMSGPLGGDQQIGGKIAQGE 89

Query: 83  IDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           + ++IF  DPL   PH+PD+ AL R+  V NIP+ATN++TA  ++ + + 
Sbjct: 90  VGLVIFLRDPLTPQPHEPDINALSRICNVHNIPIATNISTAKVLLNNLNK 139


>UniRef50_A2BWE6 Carbamoyl-phosphate synthase, large subunit n=56 Tax=cellular
            organisms RepID=A2BWE6_PROM5
          Length = 1100

 Score =  130 bits (327), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 32/144 (22%), Positives = 50/144 (34%), Gaps = 7/144 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              +   +P+     L  +D  K  L         L     L AT  T + +    G+ V+
Sbjct: 960  LASGNGVPSEGVAFLSTNDLDKDKLEEIARELIVL--GFKLIATKGTASYLL-NLGIEVD 1016

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +L    G    +  LI  G I ++I    P+ +     D   L R A  +NIP  T + 
Sbjct: 1017 EVLKVHEG-RPNIEDLIRSGLIQLVIN--TPIGSQAFHDDAY-LRRAALEYNIPTFTTIP 1072

Query: 122  TADFIIQSPHFNDAVDILIPDYQR 145
             A   +Q+        I     Q 
Sbjct: 1073 GAKAALQAIKSLRINKIDTLSLQE 1096


>UniRef50_C1MXR9 Predicted protein n=1 Tax=Micromonas pusilla CCMP1545
           RepID=C1MXR9_9CHLO
          Length = 281

 Score =  128 bits (322), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 50/139 (35%), Positives = 78/139 (56%), Gaps = 2/139 (1%)

Query: 7   TLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV-NAMLS 65
                K +ALVAH+H K  L+ +V  +        +  TG+TG+++    G+ + + + S
Sbjct: 119 KTTETKLVALVAHNHMKAPLLHFVASNMDFFSTVSIVTTGSTGSVLESNLGLTITHKVSS 178

Query: 66  GPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADF 125
           GP+GGDQ++G + S  ++    FF DPL+A PHD D+KAL R+  V N+PVATN AT   
Sbjct: 179 GPLGGDQEIGGMASLNQVGGAFFFIDPLSAHPHDDDIKALCRICNVHNVPVATNPATGKG 238

Query: 126 IIQSPHFNDAVDILIPDYQ 144
           ++ +   ND       D +
Sbjct: 239 LVYAFL-NDEYMKSTLDLK 256


>UniRef50_B0U8L9 Carbamoyl-phosphate synthase, large subunit n=3 Tax=Methylobacterium
            RepID=B0U8L9_METS4
          Length = 1157

 Score =  126 bits (317), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 26/147 (17%), Positives = 51/147 (34%), Gaps = 7/147 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              +   +P    + +   D  K  ++  V     +     + ATG T   ++   G+   
Sbjct: 1017 LGSGTQVPRAGTVFVSVRDADKARILPAVRMLAEI--GFAILATGGTQRFLAEN-GVAAT 1073

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +    + G   V   I  G+I ++    +         D ++L R A +  +P  T +A
Sbjct: 1074 RINKV-LEGRPHVVDAIKNGEIHLVF---NTTEGAGALSDSRSLRRAALLHKVPYYTTLA 1129

Query: 122  TADFIIQSPHFNDAVDILIPDYQRYLA 148
             A    +        D+ +   Q Y A
Sbjct: 1130 GAMAAAEGIRAYLGDDLEVRALQEYFA 1156


>UniRef50_Q3APN7 Carbamoyl-phosphate synthase large subunit n=11 Tax=Chlorobiaceae
           RepID=Q3APN7_CHLCH
          Length = 621

 Score =  126 bits (316), Expect = 3e-28,   Method: Composition-based stats.
 Identities = 26/150 (17%), Positives = 53/150 (35%), Gaps = 7/150 (4%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQ-MLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           +     LP    + +  +D  K   +++       +     L AT  T   ++   G+  
Sbjct: 471 QAANMQLPLSGAVFISVNDQDKNHRMLAIARSLYDMD--FDLVATAGTWQFLTDN-GIEC 527

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +      G   +   I  GK+D +I   +         D +A+   + + N+P  T +
Sbjct: 528 KKVYKVGEEGRPNIFDSIKHGKVDFVI---NTPRGEKALHDEEAIGAASVLSNVPFVTTI 584

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADR 150
             A+  +Q+       +  +   Q Y A R
Sbjct: 585 EAAEASVQAIGCIRHQEFGVKSLQEYAAYR 614


>UniRef50_A5FB35 Methylglyoxal synthase n=4 Tax=Bacteria RepID=A5FB35_FLAJ1
          Length = 133

 Score =  125 bits (315), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 47/123 (38%), Positives = 75/123 (60%), Gaps = 3/123 (2%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLL--EQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
             IA++AHD  K  L+ ++ +++ +L  E+  L  TGTTG   + A G     MLSGP+G
Sbjct: 10  MEIAIIAHDGKKADLIDFLIKNEAVLHNEKIRLIGTGTTGGK-AEAAGFKTQRMLSGPLG 68

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GD Q+   ++EG   ++ FF DPL++ PH+ D+  L+R+  V N+P+ATN ATA  ++ +
Sbjct: 69  GDAQIAGRVAEGITQMVFFFKDPLSSHPHEADINMLIRVCDVHNVPLATNEATAQLLLDA 128

Query: 130 PHF 132
              
Sbjct: 129 IAQ 131


>UniRef50_C9KKE3 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Mitsuokella
            multacida DSM 20544 RepID=C9KKE3_9FIRM
          Length = 1065

 Score =  125 bits (314), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 26/148 (17%), Positives = 53/148 (35%), Gaps = 9/148 (6%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  +   +P +  I     D  K+ +    +    L     + AT  T   I ++ G++ 
Sbjct: 917  IIGSGIHVPTKGCILFTVADKDKEEMKQLAKAFSEL--GFEICATEGTAKAI-QSMGIDA 973

Query: 61   NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDP-DVKALLRLATVWNIPVATN 119
              +          +  +I  GKI+++I   + L    H   D   + R      I   T+
Sbjct: 974  EVVGKVHERSS-DIIQMIKNGKINMVI---NTLTQGKHSAKDGFKIRRATVEHGIACLTS 1029

Query: 120  VATADFIIQSPHFNDAVDILI-PDYQRY 146
            + TA  +++   F     ++     Q Y
Sbjct: 1030 LDTAWEVLRVLSFMRERRLVYSLAIQDY 1057


>UniRef50_Q0FI67 Methylglyoxal synthase n=3 Tax=Rhodobacteraceae RepID=Q0FI67_9RHOB
          Length = 358

 Score =  124 bits (312), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 50/133 (37%), Positives = 72/133 (54%), Gaps = 1/133 (0%)

Query: 4   TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT-GMNVNA 62
                 A + IAL AHD  K  L +WV RH   LE H L  TG TG +I+ A   +++  
Sbjct: 225 ARMRSTAPRRIALAAHDTRKAHLRAWVSRHAAALEGHRLVCTGGTGQMIAEAAPQLSLRR 284

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
           +  G  GGDQQ+GA+I+ G++D +IFF DP      + D++AL RLA + + P+A   + 
Sbjct: 285 LQRGSRGGDQQLGAMIATGELDAVIFFADPTVPHGGEADLRALTRLAVLHDTPLALGPSG 344

Query: 123 ADFIIQSPHFNDA 135
           AD I  +      
Sbjct: 345 ADMIATALLAMPE 357


>UniRef50_C3XFR9 Carbamoyl-phosphate synthase subunit large n=1 Tax=Helicobacter bilis
            ATCC 43879 RepID=C3XFR9_9HELI
          Length = 1215

 Score =  123 bits (309), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 29/149 (19%), Positives = 55/149 (36%), Gaps = 8/149 (5%)

Query: 3    LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
                 LP +  I +   +  K+      +  Q +     + AT  T  ++S A G+   A
Sbjct: 1073 ACKNPLPKKGKIFISLRNSDKKHAAGLAKTLQEI--GFEIVATLGTHKILSEA-GIEAKA 1129

Query: 63   MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
            +L    G    +  +I+  +ID++I      ++    PD + +       NIP  T ++ 
Sbjct: 1130 VLKVSEG-RPHINDMIANHEIDMVIN----TSSNKAQPDARLIREAVLRANIPYFTTISG 1184

Query: 123  ADFIIQSPHFNDAVDILIPDYQRYLADRL 151
            A     +   N   +       + L D L
Sbjct: 1185 AKSAAIAMQANGNDNENTRVSTKALQDYL 1213


>UniRef50_D1CBW2 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Thermobaculum
            terrenum ATCC BAA-798 RepID=D1CBW2_THET1
          Length = 1095

 Score =  123 bits (308), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 23/140 (16%), Positives = 46/140 (32%), Gaps = 5/140 (3%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M       P    + +   DH K   +        +   + L  T  T        G+ V
Sbjct: 947  MIAAGINPPPGGSVLMSIADHEKPEALPLAAALVDM--GYALVCTEGTSTFFEDN-GIRV 1003

Query: 61   NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
            N ++         +  +I   ++ ++I    P  +     D   + R A    IP  T++
Sbjct: 1004 NQVVHKIGSVRPDITDIIRRRQVSLVIN--TPSRSGRTIRDGFEIRRAAAESGIPCLTSL 1061

Query: 121  ATADFIIQSPHFNDAVDILI 140
             TA  ++++       +I  
Sbjct: 1062 DTAKSLVKALQRRGDYNIAT 1081


>UniRef50_C0A8Y6 Carbamoyl-phosphate synthase, large subunit n=2 Tax=Bacteria
            RepID=C0A8Y6_9BACT
          Length = 1133

 Score =  122 bits (307), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 22/142 (15%), Positives = 49/142 (34%), Gaps = 7/142 (4%)

Query: 8    LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
            LP   ++ L   D  K+  +    +   L     +Y+T  T   ++   G+ V  +    
Sbjct: 995  LPTGGNVFLSVKDSDKKRAVDLARQLIKL--GFTIYSTSGTAQHLAD-CGVPVTRLAKID 1051

Query: 68   MGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFII 127
             G       +I   +I ++I   +  + +    D   +   A   ++ + T +  A   +
Sbjct: 1052 EG-RPNTIDMIKNNQIQLVI---NTPSGMIPRQDENKIRSAAYAHSVCIMTTITGAFAAL 1107

Query: 128  QSPHFNDAVDILIPDYQRYLAD 149
                   +  I +   Q Y  +
Sbjct: 1108 SGIKALKSQRIGVRPIQHYKGN 1129


>UniRef50_C0R503 Carbamoyl-phosphate synthase large subunit n=6 Tax=Wolbachia
            RepID=C0R503_WOLWR
          Length = 1151

 Score =  122 bits (306), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 26/144 (18%), Positives = 56/144 (38%), Gaps = 7/144 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP      +   D  K+ ++  V   + L     +YAT  T   ++   G+   
Sbjct: 1011 MAAGYKLPTEGAALVSVKDDDKEYILPVVRMLKELS--FEIYATKGTALYLNNN-GIAAK 1067

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            A+     G    +  ++ +GKI+++I   +    V    D K + R A + NI  +T  +
Sbjct: 1068 AVNKVREG-RPHIVDMLKDGKINLVI---NTSKGVKSVSDSKDIRRTAILQNIAYSTTAS 1123

Query: 122  TADFIIQSPHFNDAVDILIPDYQR 145
             +  ++ +  +     + +   Q+
Sbjct: 1124 GSKALVLAIQYVKNSKLEVKSLQQ 1147


>UniRef50_A7HVJ4 Carbamoyl-phosphate synthase, large subunit n=20 Tax=Bacteria
            RepID=A7HVJ4_PARL1
          Length = 1079

 Score =  121 bits (305), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 24/146 (16%), Positives = 52/146 (35%), Gaps = 7/146 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  +P    + +   D  K  +++  ++   +     L ATG T   ++   G+ V 
Sbjct: 941  LGGGTKVPVTGTVFVSVKDSDKAKIVAPAKKLLDM--GFKLVATGGTQRYLAEQ-GIEVG 997

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +    + G   +   I  G++ ++    +         D  +L R A +  +P  T VA
Sbjct: 998  TINKV-LEGRPHIVDAIKNGEVALVF---NTTEGAQALSDSMSLRRSALMMKVPYYTTVA 1053

Query: 122  TADFIIQSPHFNDAVDILIPDYQRYL 147
             A   ++         + +   Q Y+
Sbjct: 1054 GARAAVEGIDAIRKGQLEVASLQSYI 1079


>UniRef50_UPI0001B41F6C carbamoyl phosphate synthase large subunit n=2 Tax=Listeria
           monocytogenes RepID=UPI0001B41F6C
          Length = 224

 Score =  121 bits (304), Expect = 7e-27,   Method: Composition-based stats.
 Identities = 23/152 (15%), Positives = 60/152 (39%), Gaps = 9/152 (5%)

Query: 2   ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
             +  T+     + L   D  K+  +   +R   +     + AT  T + +  A+ + V+
Sbjct: 80  VASGTTMHDYGTVLLTVADRDKEEAVELAKRFNRI--GFTIMATKGTASTLEEAS-IPVS 136

Query: 62  AMLSGPMGGDQQ-VGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
            +     G +Q+ +   I  G++ +++           + D   + R +    IPV T++
Sbjct: 137 QVKKI--GENQETLIDYIRNGQVTLVVNTLTT--GKRPERDGFQIRRESVENGIPVCTSL 192

Query: 121 ATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
            TA+ I++    + + ++   +       + +
Sbjct: 193 DTAEAILRVLE-SRSFELESMNASEVKQPKSR 223


>UniRef50_A9QP20 Carbamoyl phosphate synthetase ammonia large chain n=3
            Tax=environmental samples RepID=A9QP20_9EURY
          Length = 1122

 Score =  121 bits (303), Expect = 9e-27,   Method: Composition-based stats.
 Identities = 27/138 (19%), Positives = 52/138 (37%), Gaps = 4/138 (2%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              T   +P    + +   +  K  ++   +  + +     +YAT  T +++  + G++V 
Sbjct: 979  LATELPVPTEGGVYITVKNADKHDVIPLAQELEEM--GFTIYATRGTAHVLRDSGGVDVQ 1036

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
                   G       L+ +GKI +++    P N      D   + RLA   NIP  T +A
Sbjct: 1037 TCYRITEGLTPDALDLMRQGKIHLILN--TPRNTGGAVLDGNMMRRLAVELNIPFVTTMA 1094

Query: 122  TADFIIQSPHFNDAVDIL 139
             A   +Q+          
Sbjct: 1095 GARMEVQAIAEAKEGMPE 1112


>UniRef50_Q9CKV0 Carbamoyl-phosphate synthase large chain n=6 Tax=cellular organisms
            RepID=CARB_PASMU
          Length = 1068

 Score =  120 bits (302), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 26/137 (18%), Positives = 48/137 (35%), Gaps = 6/137 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  +P    + L  +D  K  L+    + Q     + L AT  T   +    G+ V 
Sbjct: 927  LGANERIPKTGKVFLSVNDADKPRLLPIARQLQE--SGYGLCATLGTAKFLREH-GVAVQ 983

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    +   I  G+I ++I     L       D  A+ R A    + + T +A
Sbjct: 984  IINKVREG-RPNIVDAIKNGEIAMVINTVSGLA--ETVTDGHAIRRSALQQKVFLQTTLA 1040

Query: 122  TADFIIQSPHFNDAVDI 138
             A+ +  S  +    ++
Sbjct: 1041 GAEALAGSVEYLADSEV 1057


>UniRef50_C9RNJ8 Carbamoyl-phosphate synthase, large subunit n=7 Tax=Bacteria
            RepID=C9RNJ8_FIBSS
          Length = 1072

 Score =  120 bits (301), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 26/147 (17%), Positives = 49/147 (33%), Gaps = 8/147 (5%)

Query: 2    ELTTRTLPARKHIALVAHDHCK--QMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMN 59
            E     LP+   + +   D     +  +   +  Q L     +YAT  T      A G+ 
Sbjct: 925  EAAGSFLPSEGAVLISLSDKVNLSEQAIEIGKEFQKL--GFKIYATEGTAKFY-EAAGVK 981

Query: 60   VNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATN 119
               +     G    V  +I   +++++I    P        D  A+ + A  + +P  T 
Sbjct: 982  CEVVNKIAEG-RPNVLDIILNKQVNLIIN--TPWAKRDAIKDESAIRKAAIKYKVPYITT 1038

Query: 120  VATADFIIQSPHFNDAVDILIPDYQRY 146
            +A A   ++           +   Q Y
Sbjct: 1039 LAGAYNTVKGIAAARNGHGAVKSLQEY 1065


>UniRef50_B5VUE7 Diacylglycerol kinase catalytic region n=2 Tax=Arthrospira
           RepID=B5VUE7_SPIMA
          Length = 444

 Score =  118 bits (296), Expect = 5e-26,   Method: Composition-based stats.
 Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 3/140 (2%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
            IAL+AHD  ++ L+S+VE +   L  + L A   T   + + TG+ V  + S   GGD 
Sbjct: 4   TIALIAHDSQREELVSFVEENTVALSFYELIAPERTAQYLLQGTGVEVQVLSSLHHGGDI 63

Query: 73  QVGALIS-EGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
           ++   I  E +I  +IFF DP   +   P+++ L+R   + N+P+ATN ATA  ++    
Sbjct: 64  ELAYRILQETEIAAVIFFLDPGFNLSS-PEIQVLIRACNLQNVPLATNRATARAMLSGLT 122

Query: 132 FNDAV-DILIPDYQRYLADR 150
            + +   I  P      + +
Sbjct: 123 RSRSACLIFNPVSGTGNSQQ 142


>UniRef50_B4SH52 Methylglyoxal synthase-like protein n=2 Tax=cellular organisms
           RepID=B4SH52_PELPB
          Length = 328

 Score =  117 bits (293), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 42/137 (30%), Positives = 64/137 (46%), Gaps = 6/137 (4%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHV-LYATGTTGNLISRATGMNV----NAML 64
               IAL+AHD  K  ++ +   H+  L Q   + ATGTTG  ++ AT   +        
Sbjct: 190 EEMTIALIAHDDMKPRMVEFAVDHEYELGQFCAILATGTTGREVAAATNRTIGNKMIRYH 249

Query: 65  SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWN-IPVATNVATA 123
           SGP GGD ++   I  G  DV+IFF DPL+  PH  D++ +++   V + + + TN   A
Sbjct: 250 SGPKGGDIEIATAILYGHCDVVIFFVDPLSPHPHIDDIRVVVQACMVSDRVVMITNEMHA 309

Query: 124 DFIIQSPHFNDAVDILI 140
              +           L 
Sbjct: 310 REFMTRAVRGKQQLKLY 326


>UniRef50_A2QRW1 Contig An08c0170, complete genome n=337 Tax=cellular organisms
            RepID=A2QRW1_ASPNC
          Length = 2277

 Score =  116 bits (291), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 31/157 (19%), Positives = 62/157 (39%), Gaps = 19/157 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP R  +  +     K  ++  + +   +     L+AT  T + +    G+ V
Sbjct: 1393 LISTGFRLPKRNVLFSIGSYKEKMEMLPSIRKLHQI--GFNLFATSGTADFLKEN-GVPV 1449

Query: 61   NAMLSGPMGGDQQVGA------LISEGKIDVLIF------FWDPLNAVPHDPDVKALLRL 108
              +   P G ++ + +       ++   ID+ I       F  P N +          R+
Sbjct: 1450 KYLEILP-GEEEDIKSEYSLTQHLANNLIDLYINLPSNNRFRRPANYMSK---GYRTRRM 1505

Query: 109  ATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
            A  +  P+ TNV  A  +I++   + A+++   DYQ 
Sbjct: 1506 AVDYQTPLVTNVKNAKILIEAIARHFALNVQTIDYQT 1542


>UniRef50_B1YIR9 Carbamoyl-phosphate synthase large chain n=54 Tax=cellular organisms
            RepID=CARB_EXIS2
          Length = 1070

 Score =  116 bits (290), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 25/133 (18%), Positives = 53/133 (39%), Gaps = 8/133 (6%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  +   +P    + L   D  KQ ++   +R   L     L AT  T +++    G+ V
Sbjct: 925  LIASGMAIPEHGRVLLTVADQDKQEMLDLAKRFTAL--GFTLLATAGTASVLEEH-GLRV 981

Query: 61   NAMLSGPMGGDQ-QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATN 119
              +  G +G +Q  +   I + +++ +I             D   + R A   N+   T+
Sbjct: 982  QVV--GKLGSEQGSMLEWIEKAEVEYVINTM--SRDSQVTKDGFIIRRAAAENNVVCLTS 1037

Query: 120  VATADFIIQSPHF 132
            + TA+ +++    
Sbjct: 1038 LDTAEALLRVIES 1050


>UniRef50_Q9HK17 Carbamoyl-phosphate synthase large chain n=4 Tax=Thermoplasmatales
            RepID=CARB_THEAC
          Length = 1047

 Score =  115 bits (289), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 26/163 (15%), Positives = 54/163 (33%), Gaps = 23/163 (14%)

Query: 1    MELTTRTLPARKH---------------IALVAHDHCKQMLMSWVERHQPLLEQHVLYAT 45
            M+ T   +   +                + +   D  K  ++        L +   LYAT
Sbjct: 891  MKSTGEAMYPGRTLAEALRKSLQRSISSVLITVRDEDKPRIVDIARIL--LEKGVKLYAT 948

Query: 46   GTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKAL 105
              T   ++   G+    +       + ++  +IS G ID++I             D   +
Sbjct: 949  AGTSKFLADH-GIPTETLYRVRDRREPRILDMISSGSIDMVIN--TTEMTAGAVRDGFKI 1005

Query: 106  LRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLA 148
             R+  +  IP+  N+  A    ++      V++   +   YL 
Sbjct: 1006 RRICIMRGIPLIMNINLARAYAEAL---GQVEVDYREIGDYLQ 1045


>UniRef50_O93937 Aspartate carbamoyltransferase n=344 Tax=cellular organisms
            RepID=PYR1_EMENI
          Length = 2275

 Score =  114 bits (287), Expect = 7e-25,   Method: Composition-based stats.
 Identities = 32/157 (20%), Positives = 63/157 (40%), Gaps = 19/157 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP R  +  +     K  ++  + + + +     L+AT  T + +    G+ V
Sbjct: 1391 LLSTGFKLPKRNILLSIGSYKEKMEMLPSIIKLRDV--GFELFATSGTADFLKEN-GVPV 1447

Query: 61   NAMLSGPMGGDQQVGA------LISEGKIDVLIF------FWDPLNAVPHDPDVKALLRL 108
              +   P G D+ + +       ++   ID+ I       F  P N +          R+
Sbjct: 1448 KYLEILP-GEDEDIKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYMSK---GYRTRRM 1503

Query: 109  ATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
            A  +  P+ TNV  A  +I++   + A+++   DYQ 
Sbjct: 1504 AVDYQTPLVTNVKNAKILIEAIARHYALNVQTIDYQT 1540


>UniRef50_P07259 Aspartate carbamoyltransferase n=65 Tax=cellular organisms
            RepID=PYR1_YEAST
          Length = 2214

 Score =  114 bits (285), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 17/156 (10%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP +  +  +     KQ L+S V++   +   + L+AT  T + +S   G+ V
Sbjct: 1351 LLATGFKLPKKNILLSIGSYKEKQELLSSVQKLYNM--GYKLFATSGTADFLSEH-GIAV 1407

Query: 61   NAMLSGPMGGDQQ-----VGALISEGKIDVLIF------FWDPLNAVPHDPDVKALLRLA 109
              +       D Q     +   ++  +ID+ I       F  P + V          RLA
Sbjct: 1408 QYLEVLNKDDDDQKSEYSLTQHLANNEIDLYINLPSANRFRRPASYVSK---GYKTRRLA 1464

Query: 110  TVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
              +++P+ TNV  A  +I++   N  +D+   D Q 
Sbjct: 1465 VDYSVPLVTNVKCAKLLIEAISRNITLDVSERDAQT 1500


>UniRef50_UPI000197805F carbamoyl phosphate synthase large subunit n=3 Tax=Campylobacterales
            RepID=UPI000197805F
          Length = 1232

 Score =  114 bits (285), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 25/148 (16%), Positives = 47/148 (31%), Gaps = 8/148 (5%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP    + L      K+  ++       L     + AT  T  ++    G+  +
Sbjct: 1091 LACKNALPLSGEVFLSLASLDKKEGVALANDFIEL--GFSICATEGTYKILCEN-GIEAS 1147

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +L    G    +   +   +I + I   D L+      D   +       +IP  T +A
Sbjct: 1148 HILKVSEG-RPNIIDRMMNNQIALAINTSDNLSNK---DDTHLIRTQIIKSSIPYFTTLA 1203

Query: 122  TADFIIQSPHFNDAVDILIP-DYQRYLA 148
             A   I++       ++      Q YL 
Sbjct: 1204 AARVAIEAIRDIKKYNLSQAFSLQEYLE 1231


>UniRef50_C9LZI0 Carbamoyl-phosphate synthase large subunit chain n=1
           Tax=Lactobacillus helveticus DSM 20075
           RepID=C9LZI0_LACHE
          Length = 202

 Score =  113 bits (284), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 27/135 (20%), Positives = 57/135 (42%), Gaps = 15/135 (11%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
                LP   ++ L   D  K+ ++   +R   +   + ++AT  T N + +   ++V  
Sbjct: 67  GAKMQLPENGNVLLTIEDRDKEKILPIAKRFARI--GYRIFATKGTANFLKKN-DLHVEL 123

Query: 63  MLSGPMGG--DQQVGALISEGKIDVLIFFWDPLNAVPHD----PDVKALLRLATVWNIPV 116
           +            +   + +GKID++I        + HD     D   + ++A   N+P+
Sbjct: 124 VTKVHEDEQAYDNILNELRDGKIDLVIN------TMGHDIEKNSDGFIIRQMAIQQNVPL 177

Query: 117 ATNVATADFIIQSPH 131
            T + TAD +++S  
Sbjct: 178 LTALDTADALLKSLE 192


>UniRef50_B2IW98 Forkhead-associated protein n=1 Tax=Nostoc punctiforme PCC 73102
           RepID=B2IW98_NOSP7
          Length = 664

 Score =  113 bits (282), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 36/122 (29%), Positives = 63/122 (51%), Gaps = 1/122 (0%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM-G 69
            ++I L+AH+  K  L  +V +HQ    Q       + G ++ +  G+ ++     P+ G
Sbjct: 541 ERNIVLIAHESKKSELAEFVSQHQEFFSQSFTITWPSVGEVLHQQAGITISQQTPAPISG 600

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           G Q + +L+  G+I  +IF  D L   P   + +ALLRL T+  + +ATN+ TA+ I+  
Sbjct: 601 GYQTIASLVGAGEILAVIFLRDLLQPQPGQANEEALLRLCTINQVLLATNLPTAEAIVHY 660

Query: 130 PH 131
             
Sbjct: 661 LK 662


>UniRef50_B7G8W8 Predicted protein n=7 Tax=cellular organisms RepID=B7G8W8_PHATR
          Length = 1542

 Score =  112 bits (281), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 27/161 (16%), Positives = 53/161 (32%), Gaps = 11/161 (6%)

Query: 1    MELTTRTLP-ARKHIAL-VAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGM 58
            M  TT  LP   + I L +A +  ++           L   + L+ T  T        G+
Sbjct: 1357 MLSTTFKLPNKNRTILLSIASEEYRREFAEAAVILHRL--GYKLFGTPGTAAYYQDNHGI 1414

Query: 59   NVNAMLSGPMGGDQQVGA---LISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIP 115
             + ++       D   G     I  GKID++I   +             + R    + + 
Sbjct: 1415 EIKSVSKPDAETDDAPGTALHEIKNGKIDLVINVSEGATRREEITSGYIIRRAVVDFGVS 1474

Query: 116  VATNVATADFIIQSPHFNDAVDILIP----DYQRYLADRLK 152
            + T+V  A  + +           +P      Q +   +++
Sbjct: 1475 LVTDVKCAIKLAECFDRGMGDGKFVPRHIVSAQSFTRGQIQ 1515


>UniRef50_D1Y1S0 Carbamoyl-phosphate synthase, large subunit n=2 Tax=Bacteria
            RepID=D1Y1S0_9BACT
          Length = 1364

 Score =  112 bits (280), Expect = 4e-24,   Method: Composition-based stats.
 Identities = 23/154 (14%), Positives = 51/154 (33%), Gaps = 8/154 (5%)

Query: 1    MELTTRTL--PARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGM 58
            +      +       + +   D  K  ++    R   L     LY TG T   +  + G+
Sbjct: 937  LIAAGYAVRHHEPGGVLISVQDRDKPEIVELARRLASL--GCRLYTTGGTAEYLK-SRGI 993

Query: 59   NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVAT 118
               ++     G    +  L+ +G++  ++    P ++     D + L   A        T
Sbjct: 994  RSASVGKISQGNR-DIPYLLDQGRVQYVLSTSSPDSSE--RADAQVLRSKAIERRAACMT 1050

Query: 119  NVATADFIIQSPHFNDAVDILIPDYQRYLADRLK 152
            ++ TA  ++           +      +L DR +
Sbjct: 1051 SLDTARALVDCMVSGYDEGNVELVDMAHLPDRKR 1084


>UniRef50_B9L7I5 Carbamoyl-phosphate synthase, large subunit n=7 Tax=Proteobacteria
            RepID=B9L7I5_NAUPA
          Length = 1090

 Score =  111 bits (278), Expect = 7e-24,   Method: Composition-based stats.
 Identities = 27/147 (18%), Positives = 51/147 (34%), Gaps = 7/147 (4%)

Query: 3    LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
                 LP    + +   +  K+   +  +  +       + AT  T  +IS A G+    
Sbjct: 951  ACKNFLPTSGKVFISLTNIDKEFAPALAKALKN--HGFEIVATSGTYKVISEA-GIECER 1007

Query: 63   MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
            +L    G    +  +I   +I ++I   D         D K + R      IP  T +A 
Sbjct: 1008 VLKISEG-RPNIVDMIKNEEIALVINTSD---NKASKDDAKIIRREVLNQGIPYFTTIAA 1063

Query: 123  ADFIIQSPHFNDAVDILIPDYQRYLAD 149
            A   +++  F    +  +   Q Y  +
Sbjct: 1064 AFAAVEAIEFLQTSEEKVKSIQDYFKN 1090


>UniRef50_B7S3K0 Predicted protein n=1 Tax=Phaeodactylum tricornutum CCAP 1055/1
           RepID=B7S3K0_PHATR
          Length = 314

 Score =  111 bits (278), Expect = 8e-24,   Method: Composition-based stats.
 Identities = 38/147 (25%), Positives = 72/147 (48%), Gaps = 8/147 (5%)

Query: 5   TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM- 63
                  + +ALV+H+  K  +  +V  ++ +L++  L  T +T  ++S     + + + 
Sbjct: 142 AFAPSEMRCLALVSHNRMKAAMKEFVTINKNILKKFCLTGTQSTMKMLSEVFKGDSSVVF 201

Query: 64  ----LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATN 119
                SGP+GGD ++ AL+  G++  ++FF DPL+A  H  D+  L R A V N  +   
Sbjct: 202 GPSCTSGPLGGDAELAALLCRGRLGGILFFEDPLSAHAHQADIHCLCRQAQVHNTMICAT 261

Query: 120 VATADFI---IQSPHFNDAVDILIPDY 143
             +A  +   ++S    +    LIP +
Sbjct: 262 TTSALMMMHVLRSALQGNGRPELIPSF 288


>UniRef50_Q9KHE9 Carbamoyl phosphate synthetase large subunit (Fragment) n=1
           Tax=Nostoc sp. PCC 7120 RepID=Q9KHE9_ANASP
          Length = 127

 Score =  111 bits (277), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 26/133 (19%), Positives = 46/133 (34%), Gaps = 7/133 (5%)

Query: 17  VAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGA 76
              D  K   +  V     L     + AT  T  ++    G+NV  +L    G    V  
Sbjct: 1   SMSDRDKSAAVPVVREFIDL--GFKVMATFGTRRVLLEN-GLNVELVLKLHEG-RPHVID 56

Query: 77  LISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAV 136
            I   KI ++I   +  +      D + + R    + IP+ T +A A   + +       
Sbjct: 57  AIKNQKIQLII---NTPSGEEAQTDARLIRRTGLAYKIPIITTIAGAKATVAAIRSMQNT 113

Query: 137 DILIPDYQRYLAD 149
            + +   Q Y  +
Sbjct: 114 TLDVKTIQEYCPN 126


>UniRef50_Q0TM79 Carbamoyl-phosphate synthase large chain n=94 Tax=cellular organisms
            RepID=CARB_CLOP1
          Length = 1067

 Score =  110 bits (276), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 27/142 (19%), Positives = 49/142 (34%), Gaps = 7/142 (4%)

Query: 3    LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
             +  T    K I      H K+  M   +    L   +   AT  T   +  A G++   
Sbjct: 931  ASMYTGDKGKTILATIKKHDKKEFMELAKDLDKL--GYNFIATTGTAKELREA-GIDAKE 987

Query: 63   MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
            +          +  LI   +ID+++    P  A     D   + R A   NI V T++ T
Sbjct: 988  VRRIGE-ESPNIMDLIKNKEIDLVVN--TPTKANDSKRDGFHIRRAAIERNIGVMTSLDT 1044

Query: 123  ADFIIQSPHFNDAVDILIPDYQ 144
               +++      A +  +  + 
Sbjct: 1045 LKALVE-LQKEGAHNRELEVFN 1065


>UniRef50_A6CPS0 Carbamoyl-phosphate synthase large subunit n=2 Tax=Bacteria
           RepID=A6CPS0_9BACI
          Length = 167

 Score =  110 bits (275), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 21/132 (15%), Positives = 46/132 (34%), Gaps = 6/132 (4%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           +      +     + L   D  K   +   +R   +   + + AT  T +++ R   + V
Sbjct: 22  IVAAGMQMKEYGSVLLTVADKDKDEAIGLAKRFVNI--GYQILATKGTADVL-RTADIPV 78

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +      G   +  +I  G+  ++I             D   + R +    IP  T++
Sbjct: 79  KEVDKIGSEG-PTLLDVIQSGETQLVINTLT--KGKQPQRDGFRIRRESVENGIPCLTSL 135

Query: 121 ATADFIIQSPHF 132
            TA+ I++    
Sbjct: 136 DTAEAILKVFES 147


>UniRef50_Q03WW7 Carbamoyl-phosphate synthase large chain n=115 Tax=Bacteria
            RepID=CARB_LEUMM
          Length = 1059

 Score =  110 bits (275), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 22/132 (16%), Positives = 45/132 (34%), Gaps = 6/132 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
              +   +P   ++     D  K+  +   +R   L     L+AT  TG  +S    + V 
Sbjct: 926  IASNIKVPRYGNVLFTVADDDKEEALELAKRFNDL--GFALFATAGTGAYLSDN-DLPVE 982

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +       D    A + + K+ V+I           + D + +   A    +P+ T + 
Sbjct: 983  VLDKISE-SDNNAVAALRQQKVQVVIN--TTQADDRAESDGRLIRNAAIENAVPLFTALD 1039

Query: 122  TADFIIQSPHFN 133
            T    ++     
Sbjct: 1040 TVSAFLEVLESR 1051


>UniRef50_Q2FLD9 Carbamoyl-phosphate synthase large chain n=6 Tax=cellular organisms
            RepID=CARB_METHJ
          Length = 1056

 Score =  109 bits (274), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 24/148 (16%), Positives = 52/148 (35%), Gaps = 7/148 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP   ++ +   D  K  ++   +          +YAT  T    +   G+  N
Sbjct: 916  IAAHNRLPKSGNVFISVTDDLKDQILQVAKTFTE--NGLSIYATSGTVEFFAER-GITAN 972

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    V  ++  G+I ++I   +         D + ++R+A  +  P  T + 
Sbjct: 973  LVRKIAEG-SPNVLDMLRAGEISLII---NNFADKQSRHDHQQIMRVAVDYGTPYITTLQ 1028

Query: 122  TADFIIQSPHFNDAVDILIPDYQRYLAD 149
             A    ++ +     ++ I   Q Y+  
Sbjct: 1029 AAVAAAEAINSVREENLTIEPLQHYIGR 1056


>UniRef50_O50236 Carbamoyl-phosphate synthase large chain n=3 Tax=Zymomonas mobilis
            RepID=CARB_ZYMMO
          Length = 1112

 Score =  109 bits (273), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 24/145 (16%), Positives = 49/145 (33%), Gaps = 7/145 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP      +   D  K  ++  ++    L     L AT  T   + ++ G+ V 
Sbjct: 969  LAAGNALPRAGTFFISVKDSDKAQIVEPIKALTDL--GIKLVATDGTARYL-QSKGVPVE 1025

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    +  LI +G I +++   +         D  ++     +  +P  T  A
Sbjct: 1026 RVNKVREG-RPHIVDLIKDGAISLVV---NTTEGWQSLQDSASIRSSVVLAPVPYFTTAA 1081

Query: 122  TADFIIQSPHFNDAVDILIPDYQRY 146
             A    ++     A ++ +   Q Y
Sbjct: 1082 AAIVAAEAIVAIKARELEVRSLQSY 1106


>UniRef50_A9A4K3 Carbamoyl-phosphate synthase, large subunit n=5 Tax=Thaumarchaeota
            RepID=A9A4K3_NITMS
          Length = 1080

 Score =  109 bits (272), Expect = 3e-23,   Method: Composition-based stats.
 Identities = 27/153 (17%), Positives = 50/153 (32%), Gaps = 8/153 (5%)

Query: 1    MELTTRTLPARKHIALVAHDHC-KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATG-M 58
            +      LP      +       K+ L+S + + + L     + AT  T        G +
Sbjct: 929  LTSVGIKLPQTGTAVVTVGGTENKEKLLSSIAKLKQL--GFKIMATEHTAEFFEEKVGGI 986

Query: 59   NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAV---PHDPDVKALLRLATVWNIP 115
             +   +S P      +  ++ E KID +I                D   + R A    IP
Sbjct: 987  EIIHKISEPER-LPNIADMLYERKIDFIINIPSTSTIEKYVGMLDDEYQIRRKAIELGIP 1045

Query: 116  VATNVATADFIIQSPHFNDAVDILIPDYQRYLA 148
            V T +  AD  +++  +    +      + Y  
Sbjct: 1046 VLTTIELADSFVKTLEWLQHNETTKDPIEPYDP 1078


>UniRef50_B3LBP4 Carbamoyl phosphate synthetase, putative n=6 Tax=Plasmodium
            RepID=B3LBP4_PLAKH
          Length = 2169

 Score =  109 bits (272), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 28/156 (17%), Positives = 57/156 (36%), Gaps = 17/156 (10%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPL-LEQHVLYATGTTGNLIS---RAT 56
            +  T   LP +K I +   +   +  +++ E  Q L L    +YAT  T +  S    + 
Sbjct: 2005 LIATGMKLP-KKSILISIKNLNNK--LAFEEPFQLLFLMGFTIYATEGTYDFYSKFLESF 2061

Query: 57   GMN---------VNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLR 107
             +          +             +  LI   K++++I   D L       +   + R
Sbjct: 2062 NVTKGSKFHQRLIRVHNKSSENLMPNITDLIMNHKVEMVINITDTLKTKVS-SNGYKIRR 2120

Query: 108  LATVWNIPVATNVATADFIIQSPHFNDAVDILIPDY 143
            LA+ + +P+ TN+  +   I S +   +       +
Sbjct: 2121 LASDFQVPLITNMKLSSLFIDSLYRKFSRRKEKKPF 2156


>UniRef50_Q8IEN3 Carbamoyl phosphate synthetase n=3 Tax=Eukaryota RepID=Q8IEN3_PLAF7
          Length = 2375

 Score =  108 bits (269), Expect = 8e-23,   Method: Composition-based stats.
 Identities = 29/156 (18%), Positives = 59/156 (37%), Gaps = 17/156 (10%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPL-LEQHVLYATGTTGNLIS---RAT 56
            +  T   LP +K I +   +   +  +++ E  Q L L    +YAT  T +  S    + 
Sbjct: 2211 LIATGMKLP-KKSILISIKNLNNK--LAFEEPFQLLFLMGFTIYATEGTYDFYSKFLESF 2267

Query: 57   GMNV-----NAMLSGPMGGDQQVG----ALISEGKIDVLIFFWDPLNAVPHDPDVKALLR 107
             +N        ++       + +      LI   K++++I   D L       +   + R
Sbjct: 2268 NVNKGSKFHQRLIKVHNKNAENISPNTTDLIMNHKVEMVINITDTLKTKVS-SNGYKIRR 2326

Query: 108  LATVWNIPVATNVATADFIIQSPHFNDAVDILIPDY 143
            LA+ + +P+ TN+      I S +   +       +
Sbjct: 2327 LASDFQVPLITNMKLCSLFIDSLYRKFSRQKERKSF 2362


>UniRef50_C5JG53 Bifunctional pyrimidine biosynthesis protein pyrABCN n=1
            Tax=Ajellomyces dermatitidis SLH14081 RepID=C5JG53_AJEDS
          Length = 2544

 Score =  107 bits (268), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 19/157 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP +  +  +     K  ++  + +   L   + L+AT  T + +    G+ V
Sbjct: 1668 LISTGFKLPKKNVLFSIGSFKEKVEMLPSIRKLHAL--GYNLFATAGTADYLKEH-GLPV 1724

Query: 61   NAMLSGPMGGDQQVGA------LISEGKIDVLIF------FWDPLNAVPHDPDVKALLRL 108
              +     G ++ + +       ++   ID+ I       F  P N +          R+
Sbjct: 1725 KYLEVLA-GEEEDLKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYMSK---GYRTRRM 1780

Query: 109  ATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
            A  +  P+ TNV  A  +I++   +  ++++  D Q 
Sbjct: 1781 AVDYQTPLVTNVKNAKILIEAIARHYTMNVMSIDCQT 1817


>UniRef50_B9KXM5 Carbamoyl-phosphate synthase large chain n=794 Tax=cellular organisms
            RepID=CARB_THERP
          Length = 1078

 Score =  107 bits (268), Expect = 9e-23,   Method: Composition-based stats.
 Identities = 30/129 (23%), Positives = 48/129 (37%), Gaps = 7/129 (5%)

Query: 14   IALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG-GDQ 72
            + L   D+ K   +        L   H L AT  T   + RA G+ V  +    +G G  
Sbjct: 944  VLLSLADNDKSAGVELARGLLAL--GHPLVATEGTARYL-RAHGVPVE-LTVAHIGHGHP 999

Query: 73   QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
             V  +I E K+  +I    P        D   + R A    IP  T++ TA  ++++   
Sbjct: 1000 DVLEVILERKVRGVIN--TPGRDEGTIQDGFLIRRAAVERGIPCLTSLDTARALVRALLG 1057

Query: 133  NDAVDILIP 141
                  + P
Sbjct: 1058 GGTSFSVQP 1066


>UniRef50_C6Q1M4 MGS domain protein n=1 Tax=Clostridium carboxidivorans P7
           RepID=C6Q1M4_9CLOT
          Length = 159

 Score =  107 bits (268), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 30/138 (21%), Positives = 56/138 (40%), Gaps = 11/138 (7%)

Query: 3   LTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
            +   +     I +   D  K+  +  ++ +Q L      YA+  TGN +     ++   
Sbjct: 24  ASGVNIVTEGSIYVSLKDVDKKEGIDIIKDYQKL--GFKFYASEGTGNYLKGNA-IDCTI 80

Query: 63  MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
           +      GD QV   I +GKI +LI    P      + +   L R A  + +PV T + T
Sbjct: 81  I-----DGD-QVSEFIVDGKIKMLIN--TPTRGNNPESEGFKLRRKAAEYRVPVFTCIDT 132

Query: 123 ADFIIQSPHFNDAVDILI 140
           A   + + +F  + + + 
Sbjct: 133 AKIFLTAINFKKSNEKVE 150


>UniRef50_Q8UDE9 Carbamoyl-phosphate synthase large chain n=103 Tax=Proteobacteria
            RepID=CARB_AGRT5
          Length = 1162

 Score =  107 bits (267), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 26/145 (17%), Positives = 52/145 (35%), Gaps = 7/145 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP    + +   D  K+ ++S +           + ATG T   ++   G+N  
Sbjct: 1023 LGAGVDLPRSGTVFVSVRDEDKEGVLSAIRILVE--SGFKVLATGGTQRFLAEQ-GINAE 1079

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    +   I   ++ ++I   D   +     D K+L R   +  +P  T +A
Sbjct: 1080 KINKVQEG-RPHIEDAIRNRQVQLVINTTD---SNKAISDSKSLRRATLMQKVPYYTTMA 1135

Query: 122  TADFIIQSPHFNDAVDILIPDYQRY 146
             A+    +     A ++ +   Q Y
Sbjct: 1136 GAEAAALAIKALKAGNLEVKPLQSY 1160


>UniRef50_A8F453 Carbamoyl-phosphate synthase large chain n=13 Tax=Bacteria
            RepID=CARB_THELT
          Length = 1105

 Score =  106 bits (266), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 24/150 (16%), Positives = 50/150 (33%), Gaps = 18/150 (12%)

Query: 10   ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
            + K + +  +D  K+ ++  V     L     ++AT  TG ++ R+ G+ V  +     G
Sbjct: 948  STKSLLVTVNDRDKREIVPLVSYLYDL--GFEVFATAGTGKIL-RSMGIAVKNVFKVGEG 1004

Query: 70   GDQQVGALISEGKIDVLIFFWDPLNAVPHDPD--------------VKALLRLATVWNIP 115
                V  LI +GKI  ++    P      + +                 +   A    +P
Sbjct: 1005 -KPDVVDLIRQGKIGFIVITQSPNRKTSAEINREAENSFADDERTAGYKIRTAAIQCKVP 1063

Query: 116  VATNVATADFIIQSPHFNDAVDILIPDYQR 145
              T +      + +        + +   Q 
Sbjct: 1064 CITTIEAFRAEVSAIRRLKKSTLSVRSLQD 1093


>UniRef50_C0NSX2 Carbamoyl-phosphate synthase n=3 Tax=cellular organisms
            RepID=C0NSX2_AJECG
          Length = 2496

 Score =  106 bits (266), Expect = 2e-22,   Method: Composition-based stats.
 Identities = 28/157 (17%), Positives = 62/157 (39%), Gaps = 19/157 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            +  T   LP +  +  +     K  ++  + +   L   + L+AT  T + +    G+ V
Sbjct: 1620 LISTGFKLPNKNVLFSIGSFKEKVEMLPSIRKLHAL--GYNLFATAGTADYLKEH-GLPV 1676

Query: 61   NAMLSGPMGGDQQVGA------LISEGKIDVLIF------FWDPLNAVPHDPDVKALLRL 108
              +     G ++ + +       ++   ID+ I       F  P N +          R+
Sbjct: 1677 KYLDVLA-GEEEDLKSEYSLTQHLANNLIDLYINLPSSNRFRRPANYMSK---GYRTRRM 1732

Query: 109  ATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQR 145
            A  +  P+ TNV  A  +I++   + +++++  D Q 
Sbjct: 1733 AVDYQTPLVTNVKNAKLLIEAIARHYSMNVMSIDCQT 1769


>UniRef50_P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial n=86
            Tax=Deuterostomia RepID=CPSM_HUMAN
          Length = 1500

 Score =  106 bits (265), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 31/155 (20%), Positives = 58/155 (37%), Gaps = 11/155 (7%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  T   +P +  I +      +   +   E+     E   L+AT  T + ++ A  +  
Sbjct: 1350 MLSTGFKIPQKG-ILIGIQQSFRPRFLGVAEQLHN--EGFKLFATEATSDWLN-ANNVPA 1405

Query: 61   NAMLSGP-MGGDQQVGA---LISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPV 116
              +      G +  + +   LI +G ID++I   +      H  D   + R A    IP+
Sbjct: 1406 TPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVH--DNYVIRRTAVDSGIPL 1463

Query: 117  ATNVATADFIIQSPHFNDAVDILIP-DYQRYLADR 150
             TN        ++   +  VD      Y++Y A +
Sbjct: 1464 LTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGK 1498


>UniRef50_A5D508 Carbamoyl-phosphate synthase large chain n=178 Tax=cellular organisms
            RepID=CARB_PELTS
          Length = 1083

 Score =  106 bits (264), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 24/134 (17%), Positives = 42/134 (31%), Gaps = 11/134 (8%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M      + +   +     D  K   +S    +  L   + L+AT  T   +    G+ V
Sbjct: 927  MRAAGLKVASGGRVVFSVADRDKAEAVSIAGEYAAL--GYTLHATPGTARAL-EKAGLEV 983

Query: 61   NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
              +       D     LI  G + ++I    P            L R A  + +P  T++
Sbjct: 984  EVVEI----TDP--VPLIRSGTVGLIIN--TPTRGKVPGRPGFLLRRTAAEYRVPCLTSL 1035

Query: 121  ATADFIIQSPHFND 134
             TA  +        
Sbjct: 1036 DTARALAMVLRSVR 1049


>UniRef50_UPI0001B44E07 carbamoyl phosphate synthase large subunit n=8 Tax=Bacteria
           RepID=UPI0001B44E07
          Length = 211

 Score =  106 bits (264), Expect = 3e-22,   Method: Composition-based stats.
 Identities = 19/138 (13%), Positives = 46/138 (33%), Gaps = 7/138 (5%)

Query: 2   ELTTRTLPARKHIAL-VAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
               R +   + + L   ++H K   +      + L   +   AT  T   +    G+  
Sbjct: 72  LAAGRHMSDERGVVLATVNNHDKDEFIEIAXDMKEL--GYTFVATEGTAKSLREN-GIEA 128

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
           + +          +   I   ++D++I    P        D   + R A  ++  + T++
Sbjct: 129 DIVNRV-EESRPNILDAIRNKQVDIVIN--TPTKGNDSTRDGFKIRRTAIEFSTEIMTSL 185

Query: 121 ATADFIIQSPHFNDAVDI 138
            T   +++    +   D 
Sbjct: 186 DTLKALVEVKKKHLNKDE 203


>UniRef50_A3YU56 Methylglyoxal synthase n=2 Tax=Synechococcus RepID=A3YU56_9SYNE
          Length = 434

 Score =  105 bits (263), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 4/141 (2%)

Query: 14  IALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISR---ATGMNVNAMLSGPMGG 70
           IAL+A     + L+ W+E+HQ LLE   L A       ++    ++G+ V+ + +   GG
Sbjct: 5   IALLASAGSNERLLGWLEQHQVLLEGFPLLAPAELVLALAEDQRSSGLKVSPLATLAAGG 64

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
           D Q+   +  G +  ++FF DP   +   PD++ LLR   +  IP+A N ATA   ++  
Sbjct: 65  DIQIAERVLAGAVGAVLFFVDPATTLATTPDLRLLLRTCALAGIPLALNEATATLALRGL 124

Query: 131 HFND-AVDILIPDYQRYLADR 150
             +  A  I  P   +   ++
Sbjct: 125 GRSRLAYLIFNPVAGQGEPNQ 145


>UniRef50_Q9ZKT2 Carbamoyl-phosphate synthase large chain n=422 Tax=cellular organisms
            RepID=CARB_HELPJ
          Length = 1085

 Score =  105 bits (263), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 22/143 (15%), Positives = 48/143 (33%), Gaps = 9/143 (6%)

Query: 6    RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLS 65
              +  +  I +   D  K+     ++R   L     L  T  T   +    G+    +L 
Sbjct: 952  NPIKNKGLIFVSIKDKDKEEACVLMKRLVEL--GFELCTTEGTHKAL-EKAGVKSLKVLK 1008

Query: 66   GPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADF 125
               G    +  L+  G+I + I   D         D K +       ++   T ++  + 
Sbjct: 1009 ISEG-RPNIMDLMMNGEISMAINTSD----HKSQDDAKLIRASVLKNHVSYFTTLSAIEV 1063

Query: 126  IIQSPHFNDAVDILIPDYQRYLA 148
            ++ +   + + +  +   Q YL 
Sbjct: 1064 LLLALEES-SQEDELLALQDYLK 1085


>UniRef50_A6LPD9 Carbamoyl-phosphate synthase large chain n=23 Tax=Firmicutes
            RepID=CARB_CLOB8
          Length = 1069

 Score =  105 bits (263), Expect = 4e-22,   Method: Composition-based stats.
 Identities = 20/135 (14%), Positives = 44/135 (32%), Gaps = 6/135 (4%)

Query: 10   ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMG 69
             +  I    + H K   +   +    +   +   AT  T  L+  A G+ V  +      
Sbjct: 938  EKGKILATINKHDKAEFLPIAKDLASV--GYKFIATSGTCALLKEA-GIEVEEIRKIDE- 993

Query: 70   GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
             +  +  ++   ++D+++    P        D   + R A   N+ V T + T   I   
Sbjct: 994  EEPNILDIVKNREVDLVVN--TPTKGNDSKRDGFLIRRAAVERNLGVITALDTLRAIADV 1051

Query: 130  PHFNDAVDILIPDYQ 144
                   +  +  + 
Sbjct: 1052 ELEKFDENKDLEVFN 1066


>UniRef50_D0J1U7 Methylglyoxal synthase n=3 Tax=Comamonadaceae RepID=D0J1U7_COMTE
          Length = 291

 Score =  104 bits (261), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 36/126 (28%), Positives = 59/126 (46%), Gaps = 11/126 (8%)

Query: 10  ARKHIALVAHDHCKQMLMSWVERHQPLLEQHVL-YATGTTGNLISR---ATGMN-----V 60
             + +AL+AHD  K  ++ +   +  LL ++     TGTTG  ++    + G       V
Sbjct: 155 ENQTLALIAHDAMKPTMLDFAAHNFELLSRYRRRVGTGTTGQKLNEMAWSKGWPADKPWV 214

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRL--ATVWNIPVAT 118
           +   SGP+GGD Q+  L+ E +    IFF DP  A  H+ D++ L R       +   +T
Sbjct: 215 DRYNSGPLGGDAQIADLVLEKRCHRAIFFEDPHVARQHEADIQLLERAVTTVTHDAVCST 274

Query: 119 NVATAD 124
           +   A 
Sbjct: 275 SPQVAQ 280


>UniRef50_Q17XX3 Carbamoyl-phosphate synthase large chain n=7 Tax=Helicobacter
            RepID=Q17XX3_HELAH
          Length = 1133

 Score =  103 bits (258), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 23/143 (16%), Positives = 49/143 (34%), Gaps = 9/143 (6%)

Query: 6    RTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLS 65
              +  +  I +   D  K+     ++R   L     L AT  T   + +A  +    +L 
Sbjct: 1000 NPIKNKGLIFVSIKDKDKEEACVLMKRLVQL--GFELCATEGTHKALEKAR-VKSLKVLK 1056

Query: 66   GPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADF 125
               G    +  L+  G+I + I   D         D K +       ++   T ++  + 
Sbjct: 1057 ISEG-RPNIMDLMMNGEISMAINTSD----HKSQDDAKLIRASVLKNHVSYFTTLSAIEV 1111

Query: 126  IIQSPHFNDAVDILIPDYQRYLA 148
            ++ +   +   +  +   Q YL 
Sbjct: 1112 LLLALEES-PEEDALLALQDYLK 1133


>UniRef50_B8GEA3 Carbamoyl-phosphate synthase large chain n=2 Tax=Euryarchaeota
            RepID=CARB_METPE
          Length = 1056

 Score =  103 bits (258), Expect = 1e-21,   Method: Composition-based stats.
 Identities = 25/148 (16%), Positives = 52/148 (35%), Gaps = 7/148 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP   ++ +      K+ +     + + L     L+ T  T   + +A G+  N
Sbjct: 914  ISADNELPIEGNVFISVSTEQKEEVRRIAAQLRDL--GLTLFGTKGTVETLMQA-GIEAN 970

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    V  ++ +G+I ++I   +         D   ++R A  + IP  T + 
Sbjct: 971  LVRKVQEG-SPNVIDMVRKGEIRLII---NTPVDKQSRLDHYQIMRAAVDYGIPYITTLQ 1026

Query: 122  TADFIIQSPHFNDAVDILIPDYQRYLAD 149
             A     +        I +     YL++
Sbjct: 1027 AARAAALAIDAIKREKITLEPISHYLSE 1054


>UniRef50_A0YM60 Putative uncharacterized protein n=1 Tax=Lyngbya sp. PCC 8106
           RepID=A0YM60_9CYAN
          Length = 265

 Score =  103 bits (257), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 2/121 (1%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPM-- 68
           RK++ L+A +     L+ WV++   +L    ++A       + +   +NV  +++  +  
Sbjct: 143 RKYMILMADETKMSDLLDWVQKEIDILYNIPIFAPEWVAQSLQQNINLNVKQVINSNVLV 202

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
           GG   +GA I  G I  ++ F DPL   P+   + A+LRL     +  ATN+ TA  I+ 
Sbjct: 203 GGSDTIGAQIILGNIKAVVCFRDPLARRPNRASIDAILRLCDASQVICATNIQTARAILT 262

Query: 129 S 129
           +
Sbjct: 263 A 263


>UniRef50_C1A4I5 Carbamoyl-phosphate synthase large chain n=223 Tax=cellular organisms
            RepID=CARB_GEMAT
          Length = 1094

 Score =  103 bits (257), Expect = 2e-21,   Method: Composition-based stats.
 Identities = 25/145 (17%), Positives = 45/145 (31%), Gaps = 7/145 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                  LP    +     D  K    S   +   +     + AT  T        G+ V 
Sbjct: 933  LAADNALPREGTVFFTVSDGDKPTAASLAGKFHSI--GFSIMATSGTAAFFREQ-GIPVT 989

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
            ++L    G        I  G++ +L+    PL       D K L + A    +P  T + 
Sbjct: 990  SVLKVHEG-RPHGVDKILNGEVQLLVN--TPLGKHAQVDDEK-LRQAAIANRLPYTTTLT 1045

Query: 122  TADFIIQSPHFNDAVDILIPDYQRY 146
             A    ++       + ++   Q +
Sbjct: 1046 AASAAFEAIAARRTREPVVRSLQEW 1070


>UniRef50_C6XKE0 MGS domain protein n=1 Tax=Hirschia baltica ATCC 49814
           RepID=C6XKE0_HIRBI
          Length = 493

 Score =  101 bits (251), Expect = 9e-21,   Method: Composition-based stats.
 Identities = 25/128 (19%), Positives = 41/128 (32%), Gaps = 8/128 (6%)

Query: 1   MELTTRTLPARKHIALVA-HDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMN 59
           M          + + + A     KQ L+        +     ++AT  T   +  A  + 
Sbjct: 19  MLSKG----RERALLISAGSPDDKQFLLESCRNMADI--GVNIFATPGT-QRLFEAQNIK 71

Query: 60  VNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATN 119
            +       G    +  LI  G+ID +I             D K +  LA    IP+ T+
Sbjct: 72  SSPAHKISSGTQPNIKNLIENGEIDFVINILTGEQDYDEGSDAKQIRSLAIKHGIPLITD 131

Query: 120 VATADFII 127
              A   I
Sbjct: 132 REVARETI 139


>UniRef50_Q05TV7 Methylglyoxal synthase n=1 Tax=Synechococcus sp. RS9916
           RepID=Q05TV7_9SYNE
          Length = 435

 Score =  101 bits (251), Expect = 9e-21,   Method: Composition-based stats.
 Identities = 34/142 (23%), Positives = 57/142 (40%), Gaps = 4/142 (2%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT---GMNVNAMLSGPMG 69
            + L A       L +W+  +  LL    L         + R     G+++    +   G
Sbjct: 4   TLVLNADPVVCPALGTWMTNNTQLLSGFSLLIGEDVIEELKRRHDLGGLSITPCRAIREG 63

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           GD  + A I EG+I  L+ F  P +    D   + L+R A + + P+A N ATA  ++Q 
Sbjct: 64  GDIAIAARILEGEISGLVHFPAPADQQGRDVLAEPLVRAALLCDRPIALNPATASALLQG 123

Query: 130 PHFN-DAVDILIPDYQRYLADR 150
              +     I  P   +   D+
Sbjct: 124 VKRSRRGYLIFNPVAGQGDPDQ 145


>UniRef50_P05990 Dihydroorotase n=643 Tax=cellular organisms RepID=PYR1_DROME
          Length = 2224

 Score =  101 bits (251), Expect = 1e-20,   Method: Composition-based stats.
 Identities = 26/152 (17%), Positives = 55/152 (36%), Gaps = 19/152 (12%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  T   +P    +  +     K  L+  +     +   + LYA+  TG+  +   G+NV
Sbjct: 1317 MMSTGFQIPKNAVLLSIGSFKHKMELLPSIRDLAKM--GYKLYASMGTGDFYAEH-GVNV 1373

Query: 61   NAMLSGPM--------GGDQQVGALISEGKIDVLIFFWDPLNAVPHD------PDVKALL 106
             ++             G  + +   ++  + D++I    P++                  
Sbjct: 1374 ESVQWTFDKTTPDDINGELRHLAEFLANKQFDLVINL--PMSGGGARRVSSFMTHGYRTR 1431

Query: 107  RLATVWNIPVATNVATADFIIQSPHFNDAVDI 138
            RLA  ++IP+ T+V     +++S   N     
Sbjct: 1432 RLAVDYSIPLVTDVKCTKLLVESMRMNGGKPP 1463


>UniRef50_Q1RKZ5 IP15551p (Fragment) n=1 Tax=Drosophila melanogaster
           RepID=Q1RKZ5_DROME
          Length = 746

 Score =   99 bits (248), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 26/152 (17%), Positives = 55/152 (36%), Gaps = 19/152 (12%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M  T   +P    +  +     K  L+  +     +   + LYA+  TG+  +   G+NV
Sbjct: 83  MMSTGFQIPKNAVLLSIGSFKHKMELLPSIRDLAKM--GYKLYASMGTGDFYAEH-GVNV 139

Query: 61  NAMLSGPM--------GGDQQVGALISEGKIDVLIFFWDPLNAVPHD------PDVKALL 106
            ++             G  + +   ++  + D++I    P++                  
Sbjct: 140 ESVQWTFDKTTPDDINGELRHLAEFLANKQFDLVINL--PMSGGGARRVSSFMTHGYRTR 197

Query: 107 RLATVWNIPVATNVATADFIIQSPHFNDAVDI 138
           RLA  ++IP+ T+V     +++S   N     
Sbjct: 198 RLAVDYSIPLVTDVKCTKLLVESMRMNGGKPP 229


>UniRef50_UPI0001C31DA7 carbamoyl-phosphate synthase, large subunit n=1 Tax=Conexibacter
            woesei DSM 14684 RepID=UPI0001C31DA7
          Length = 1042

 Score = 99.6 bits (247), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 26/141 (18%), Positives = 42/141 (29%), Gaps = 7/141 (4%)

Query: 5    TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML 64
               LP+   + +   D  K            L     + AT  T   I R  G+ V A+ 
Sbjct: 893  GSVLPSEGTVFITVTDGDKPAAAGVAMALHGL--GFRIVATAGTAQAIKR-MGIPVEALE 949

Query: 65   SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
                G    V  LI  G++ +++   +         D   +   A    IP  T +  A 
Sbjct: 950  KIGSG-SPNVLELIERGEVKLVV---NTPVGTGARIDGWEIRSAAIAAGIPCITTMTGAM 1005

Query: 125  FIIQSPHFNDAVDILIPDYQR 145
               Q+          +   Q 
Sbjct: 1006 AAAQAIAAGARGVPAVIALQE 1026


>UniRef50_C8PAM0 Carbamoyl-phosphate synthase n=4 Tax=Lactobacillus RepID=C8PAM0_9LACO
          Length = 1055

 Score = 99.6 bits (247), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 27/130 (20%), Positives = 58/130 (44%), Gaps = 6/130 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
            E +  T+P+   + +   D  K+  +S   R   L     L AT  T N+++   G+  +
Sbjct: 923  EASNLTIPSYGTVFISVKDSDKKSAISVAARFHKL--GFQLLATEGTANILAEE-GITTS 979

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G +  +   I++ KI+++I   +  ++  H  D   +   A   +IPV +++ 
Sbjct: 980  IVEKLQTG-NNSLLEKIAQHKINLVINVTNLSDSASH--DAIMIKDQALNTHIPVFSSIQ 1036

Query: 122  TADFIIQSPH 131
            +A+ I+    
Sbjct: 1037 SAENILNVLE 1046


>UniRef50_C0AZ23 Putative uncharacterized protein n=1 Tax=Proteus penneri ATCC 35198
           RepID=C0AZ23_9ENTR
          Length = 165

 Score = 99.6 bits (247), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 22/130 (16%), Positives = 44/130 (33%), Gaps = 7/130 (5%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
           M  +  T+  +    L   +  K+ ++    +   L     L AT  T  ++  A G+N 
Sbjct: 22  MLGSNSTMKKKGRALLSVREGDKKRVVDLATKL--LKSGFELDATHGTAIVLGEA-GINP 78

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
             +     G    +   I  G+ D ++   +  +      D K + R A  + +   T +
Sbjct: 79  RLVNKVHEG-RPHIEDRIKNGEYDYIV---NTTSGRQAIEDSKIIRRSALRYKVHYDTTL 134

Query: 121 ATADFIIQSP 130
                   S 
Sbjct: 135 NGGFATTLSL 144


>UniRef50_A8JIR0 Carbamoyl phosphate synthase, large subunit n=1 Tax=Chlamydomonas
            reinhardtii RepID=A8JIR0_CHLRE
          Length = 1075

 Score = 99.6 bits (247), Expect = 3e-20,   Method: Composition-based stats.
 Identities = 28/146 (19%), Positives = 48/146 (32%), Gaps = 6/146 (4%)

Query: 5    TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML 64
             + LP    + +   D  K  ++        L     L AT  T   + R  G+    + 
Sbjct: 926  GQKLPKTGKVFVSMADKYKPDIIEIARNLGNL--GFGLVATTGTALAL-RNAGVPCEQVF 982

Query: 65   SGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATAD 124
                G       L+  G++ +++             D K L RLA   +IP  T VA A 
Sbjct: 983  KIQEG-RPNPADLMRNGEVTLMM--MTSGGDEADLRDGKELRRLALQLSIPTVTTVAGAR 1039

Query: 125  FIIQSPHFNDAVDILIPDYQRYLADR 150
                +     A  ++    Q +  + 
Sbjct: 1040 ATTAALRAMRAGPLVQIPLQDFFPNY 1065


>UniRef50_A9V282 Predicted protein n=2 Tax=cellular organisms RepID=A9V282_MONBE
          Length = 1920

 Score = 98.8 bits (245), Expect = 5e-20,   Method: Composition-based stats.
 Identities = 25/142 (17%), Positives = 51/142 (35%), Gaps = 13/142 (9%)

Query: 1    MELTTRTLP-ARKHIALVAHDHC-KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGM 58
            M  T+  LP  + ++ L    +  K   +    R Q L     L+ +  T +    + G+
Sbjct: 1076 MISTSFRLPRPQGNVLLSIGGYDGKLEFLDSTRRLQQL--GFKLFGSMGTADFYL-SHGV 1132

Query: 59   NVNAMLSGPMGGDQQ-VGALISEGKIDVLIFFWDPLNAVPHDP-----DVKALLRLATVW 112
             +  +       D + +   + +G  D++I    P+      P           R+A   
Sbjct: 1133 EIKPVDWLADTEDIESIKDNLLDGHYDMVINL--PMRNKYRRPASYMTSGSLARRMAVES 1190

Query: 113  NIPVATNVATADFIIQSPHFND 134
             +P+ TN+  A   I +    +
Sbjct: 1191 KVPLITNIKCAKLFIAALGSEN 1212


>UniRef50_D2LJN2 MGS domain protein n=1 Tax=Rhodomicrobium vannielii ATCC 17100
           RepID=D2LJN2_RHOVA
          Length = 481

 Score = 98.0 bits (243), Expect = 8e-20,   Method: Composition-based stats.
 Identities = 24/136 (17%), Positives = 51/136 (37%), Gaps = 7/136 (5%)

Query: 1   MELTTRTL---PARKHIALVA-HDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT 56
           M      L    +RK + + A  +  K  ++  +++   L     ++AT  T   ++R  
Sbjct: 9   MLAFNLKLLGRKSRKKVLISAGKEDDKARMLPAIKQFLSLE--VDVFATPGTHRFLTRH- 65

Query: 57  GMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPV 116
           G++   +     G    +   ++E + D++I      N      D K + +L     IP+
Sbjct: 66  GIDTVEIHKITDGRAPNIRTFLNENRFDLVINVLTGDNDYDESSDAKLIRKLCIENGIPL 125

Query: 117 ATNVATADFIIQSPHF 132
            T+       +Q    
Sbjct: 126 ITDCDVGIETLQQIVR 141


>UniRef50_C5KGZ1 Putative uncharacterized protein n=1 Tax=Perkinsus marinus ATCC 50983
            RepID=C5KGZ1_9ALVE
          Length = 1533

 Score = 95.7 bits (237), Expect = 4e-19,   Method: Composition-based stats.
 Identities = 26/136 (19%), Positives = 50/136 (36%), Gaps = 8/136 (5%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATG---M 58
                 TLP +  +  +  +  K+  + W      L   + L+AT +T  ++         
Sbjct: 1402 LSAGYTLPTKTILVSIGPEQQKEEFLPWASILISL--GYHLFATRSTYQVMKDKLNPSQS 1459

Query: 59   NVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVP-HDPDVKALLRLATVWNIPVA 117
            ++  +       +  V  LI  GKID+ I    P +A      +   + RLA      + 
Sbjct: 1460 SLTLVYKPYARREPNVKTLIQNGKIDMCIVI--PSSADSCAITEGFEMRRLAVDTRTALI 1517

Query: 118  TNVATADFIIQSPHFN 133
             ++  A F++ S    
Sbjct: 1518 NDIKEATFLVLSLEKK 1533


>UniRef50_Q1GA90 Carbamoyl-phosphate synthase, large chain n=28 Tax=Lactobacillus
            RepID=Q1GA90_LACDA
          Length = 1063

 Score = 94.9 bits (235), Expect = 8e-19,   Method: Composition-based stats.
 Identities = 24/131 (18%), Positives = 49/131 (37%), Gaps = 6/131 (4%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
            E +   +P+   I     D  KQ + +  +R   L     + AT  T N+++ A G+   
Sbjct: 931  EASDLHIPSYGTIFFSVSDEEKQEVANLAKRFARL--GFKITATEGTANILAEA-GITTG 987

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
             +     G    +   I   +I +++   +   +     D   +   A   +IPV +++ 
Sbjct: 988  VIAKIQEGSR-NLLERIQTHRIVMVVNVVNL--SDSAVEDSIKIKDQALNTHIPVFSSLE 1044

Query: 122  TADFIIQSPHF 132
            T   I+     
Sbjct: 1045 TVQLILDVLES 1055


>UniRef50_B8DTW3 Carbamoyl-phosphate synthase large chain n=400 Tax=cellular organisms
            RepID=CARB_BIFA0
          Length = 1136

 Score = 93.8 bits (232), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 28/159 (17%), Positives = 58/159 (36%), Gaps = 23/159 (14%)

Query: 8    LPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP 67
            LP   ++ +  +D  K+ L  +  R   L     ++AT  T +++ R  G+    +    
Sbjct: 966  LPTNGNVFISVNDTDKRQLPLFAVRLVEL--GFEIWATEGTASVLRR-YGIESKIVDKIH 1022

Query: 68   MGGD-----------------QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLAT 110
               D                 + V  LI EG+ID+++   +  N+     D  ++   A 
Sbjct: 1023 SRVDTDPEHPIEIQHAAGSVGKNVVELIEEGQIDLIL---NTPNSRGSRSDGYSIRAAAI 1079

Query: 111  VWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLAD 149
              +IP  T +     ++ +       D  +   Q +  +
Sbjct: 1080 AADIPQYTTMTEFSAVLLAIEAVKKNDYEVMSIQEHSRE 1118


>UniRef50_A5FYW1 Methylglyoxal synthase-like protein n=4 Tax=Proteobacteria
           RepID=A5FYW1_ACICJ
          Length = 318

 Score = 93.4 bits (231), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 41/134 (30%), Positives = 55/134 (41%), Gaps = 22/134 (16%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQH-VLYATGTTGNLIS------------------ 53
            I L+AHD  K +++ +  RH  LL +     ATGTTG L++                  
Sbjct: 173 TIGLIAHDTQKPVMLDFARRHHALLSRFGRRLATGTTGGLLNGTVPARLRAETATLLPLL 232

Query: 54  --RATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATV 111
                G    A  SGP GGD Q+   + EG+   LIFF DP  A  H+ D++ L R    
Sbjct: 233 PPAVPGWT-TAFQSGPRGGDAQIAEEVLEGRCRRLIFFEDPHVAREHEADIQLLERATRF 291

Query: 112 WNIPVATNVATADF 125
                     TA  
Sbjct: 292 APDGCLCINDTASA 305



 Score = 49.1 bits (116), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 30/138 (21%), Positives = 53/138 (38%), Gaps = 14/138 (10%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQM----LMSWVERHQPLLEQ--HVLYATGTTGNLISR 54
           M+        R  I + A    +      L   +    P L      L+A G T + I  
Sbjct: 1   MDGAAAGEGGRLRIGIAASAAMRSSEVSPLFGLLRDFAPFLSSPAVALHAVGATCDAILA 60

Query: 55  A---TGMNVNAMLSGPMGGDQQVGALI---SEGK--IDVLIFFWDPLNAVPHDPDVKALL 106
           +    G     +     GG   + +++   +EG+  +D +I+  DP++ +   P+++AL 
Sbjct: 61  SGLLAGNPPARLRPAREGGVITLTSMVVPDAEGRAALDFVIYLIDPVDPIGVFPEMQALK 120

Query: 107 RLATVWNIPVATNVATAD 124
           R   V   P  TN   A 
Sbjct: 121 RQCVVHGRPFLTNRGAAS 138


>UniRef50_B6KSM2 Carbamoyl phosphate synthetase II n=4 Tax=Toxoplasma gondii
            RepID=B6KSM2_TOXGO
          Length = 1699

 Score = 93.4 bits (231), Expect = 2e-18,   Method: Composition-based stats.
 Identities = 30/192 (15%), Positives = 60/192 (31%), Gaps = 52/192 (27%)

Query: 1    MELTTRTLP-ARKHIALVAHDH-CKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA--- 55
            +      LP  ++ I + A     K  L  + +    L     +YAT  T   +  +   
Sbjct: 1498 LISAGVPLPLEKRTILISAGPLWSKMELEPYFKILLDL--GFTIYATEGTYRFLMNSVVR 1555

Query: 56   ---------------TGMN--------------------VNAMLS-------GPMGGD-- 71
                           +G+                     +  +            GG   
Sbjct: 1556 GQGTHLPGNASPASDSGLRTPTTAESDADACICAKYASRIIRVRKPIVGSNESHNGGHQS 1615

Query: 72   QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPH 131
                +LI  GK++++I   D +N      +   + R AT   +P+ TNV  A   +++ +
Sbjct: 1616 PHALSLIESGKVEMVINVPDSMN-HRAATNGYLMRRTATDCGVPLLTNVKVASMFVEALN 1674

Query: 132  FNDAVDILIPDY 143
              +A +     +
Sbjct: 1675 KKEAKEAQGRSF 1686


>UniRef50_A6SWW2 Uncharacterized conserved protein n=12 Tax=cellular organisms
           RepID=A6SWW2_JANMA
          Length = 315

 Score = 91.8 bits (227), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 42/107 (39%), Positives = 58/107 (54%), Gaps = 11/107 (10%)

Query: 14  IALVAHDHCKQMLMSWVERHQPLLEQHVL-YATGTTGNLIS--------RATGMN-VNAM 63
           IA++AHD  K  ++   ERH  LL+Q     ATGTTG+L++           G N V   
Sbjct: 177 IAMIAHDAMKGRMLEIAERHFDLLDQFGFRCATGTTGSLLNKLAQKIKGEEAGRNWVKPY 236

Query: 64  LSGPMGGDQQVGALISEG-KIDVLIFFWDPLNAVPHDPDVKALLRLA 109
           LSGPMGGD Q+  LI +  +   ++F  DP  A  H+ D++ L R A
Sbjct: 237 LSGPMGGDAQIAELILDKDQCRRVLFLEDPHVARQHEADIQLLERAA 283



 Score = 39.1 bits (90), Expect = 0.041,   Method: Composition-based stats.
 Identities = 13/73 (17%), Positives = 32/73 (43%), Gaps = 4/73 (5%)

Query: 60  VNAMLSGPMGGDQQVGALISE----GKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIP 115
           +     G  GG  ++ + + +     ++D +++  DP++     P+  AL R   +   P
Sbjct: 80  IERFPYGRHGGLMKLVSRVVDTDPARRLDAVMYLMDPVDPSSIFPEAVALKRQCVIHGKP 139

Query: 116 VATNVATADFIIQ 128
             + +A A   ++
Sbjct: 140 FLSTLAGAREWLE 152


>UniRef50_UPI000194C4F6 PREDICTED: similar to carbamoylphosphate synthetase 2/aspartate
            transcarbamylase/dihydroorotase, partial n=1
            Tax=Taeniopygia guttata RepID=UPI000194C4F6
          Length = 1899

 Score = 89.5 bits (221), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 22/152 (14%), Positives = 51/152 (33%), Gaps = 17/152 (11%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  T   +P +  +  +     K  L+  V   + L   + LYA+  T +  +   G+ V
Sbjct: 1036 MLSTGFKIPKKNILLTIGSYKNKSELLPTVRTLENL--GYNLYASLGTADFYTEH-GIKV 1092

Query: 61   NAMLS----------GPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPD----VKALL 106
             A+            G     + +   ++E   +++I      +                
Sbjct: 1093 KAVDWHFEEADSSEAGARETQRSILDYLAENHFEMVINLSMRNSGGRRLSSFVTKGYRTR 1152

Query: 107  RLATVWNIPVATNVATADFIIQSPHFNDAVDI 138
            RLA  +++P+  ++      +++     A   
Sbjct: 1153 RLAVDYSVPLIIDIKCTKLFVEALGQIGAAPP 1184


>UniRef50_Q4SZL4 Chromosome 14 SCAF11586, whole genome shotgun sequence. (Fragment)
            n=3 Tax=cellular organisms RepID=Q4SZL4_TETNG
          Length = 2178

 Score = 88.4 bits (218), Expect = 6e-17,   Method: Composition-based stats.
 Identities = 23/164 (14%), Positives = 53/164 (32%), Gaps = 16/164 (9%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  T   +P +  +  +     K  L+  V+  + L   + LYA+  T +  +   G+ V
Sbjct: 1185 MLSTGFKIPKKNILLSIGSYKNKSELLPTVQALESL--GYDLYASLGTADFYTEH-GVKV 1241

Query: 61   NAMLSGPMGGDQ---------QVGALISEGKIDVLIFFWDPLNAVPHDPD----VKALLR 107
             A+       D           +   + E   D+++      +                R
Sbjct: 1242 TAVDWPFEEDDNGCPTKEKQRSIMNYLEENHFDLVVNLSMRNSGGRRLSSFVTKGYRTRR 1301

Query: 108  LATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRL 151
            +A  +++P+  ++      +Q+         +        + RL
Sbjct: 1302 MAVDYSVPLIIDIKCTKLFVQALRQIGRAPPVKTHIDSMTSQRL 1345


>UniRef50_C1TLQ6 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Dethiosulfovibrio
            peptidovorans DSM 11002 RepID=C1TLQ6_9BACT
          Length = 1044

 Score = 86.5 bits (213), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 17/129 (13%), Positives = 42/129 (32%), Gaps = 10/129 (7%)

Query: 2    ELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVN 61
                 ++P +  +     D  K    +     +   +   +  T  T    SR     V+
Sbjct: 923  VGAGWSVPRKGRVLFSVDDGKKAEACAIAALFES--KGWEVEGTPGTAYFFSR---WGVS 977

Query: 62   AMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVA 121
                    G   + A +++G+ D+++    P   +    +   + R A   + P   ++ 
Sbjct: 978  CRSVVKKDG---LSASLNDGRWDLVVNLPGP--DLGAIKEGAGIRRNAMETSTPCLFSLE 1032

Query: 122  TADFIIQSP 130
             A  +  + 
Sbjct: 1033 AASAVAMAL 1041


>UniRef50_P27708 Dihydroorotase n=533 Tax=cellular organisms RepID=PYR1_HUMAN
          Length = 2225

 Score = 80.7 bits (198), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 22/149 (14%), Positives = 51/149 (34%), Gaps = 14/149 (9%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  T   +P +  +  +     K  L+  V   + L   + LYA+  T +  +   G+ V
Sbjct: 1303 MLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESL--GYSLYASLGTADFYTEH-GVKV 1359

Query: 61   NAMLS---GPMGGD--QQ--VGALISEGKIDVLIFFWDPLNAVPHDPD----VKALLRLA 109
             A+       + G+   Q  +   ++E   +++I                       RLA
Sbjct: 1360 TAVDWHFEEAVDGECPPQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLA 1419

Query: 110  TVWNIPVATNVATADFIIQSPHFNDAVDI 138
              +++P+  ++      +++         
Sbjct: 1420 ADFSVPLIIDIKCTKLFVEALGQIGPAPP 1448


>UniRef50_UPI00017430FF carbamoyl phosphate synthase large subunit n=1 Tax=candidate
           division TM7 single-cell isolate TM7a
           RepID=UPI00017430FF
          Length = 104

 Score = 79.9 bits (196), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 19/96 (19%), Positives = 36/96 (37%), Gaps = 5/96 (5%)

Query: 39  QHVLYATGTTGNLISRATGMNVNAMLSGPMGG--DQQVGALISEGKIDVLIFFWDPLNAV 96
            + + AT  T        G++V  +      G  +  V  LI +G +D++I         
Sbjct: 4   GYHIMATKGTAKYFEDK-GLHVETVGKIDEEGIYEHDVLGLIYKGLVDMVINTA--AKKK 60

Query: 97  PHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
               D   + R A+   I   T++ T D +++    
Sbjct: 61  TARNDGFKIRRAASEQEIACLTSLDTTDALLKVLES 96


>UniRef50_Q4UD12 Carbamoyl phosphate synthase II, putative n=2 Tax=Theileria
            RepID=Q4UD12_THEAN
          Length = 1700

 Score = 72.2 bits (176), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 33/194 (17%), Positives = 58/194 (29%), Gaps = 49/194 (25%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLE-QHVLYATGTTGNLIS------ 53
            M  +   +P R  + L       + +  +  + + LL     +YAT  T + I       
Sbjct: 1509 MTASGMKIPERG-VLLSLGSTVNKFI--FSRKIKGLLSLGLDVYATEGTYDYIRKLWDSE 1565

Query: 54   -----RATGMNVNAMLSGPMG---------------------------GDQQVGALISEG 81
                     ++   M    +                            G   V  LIS  
Sbjct: 1566 RLFYNEEHELDRQFMTKLNLDDFEFDFEPTNMGEFKKVFKPTVQGNSTGTPDVYELISNR 1625

Query: 82   KIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVD---- 137
            K+D+LI   D +N          + R      I + T    A  +I +  +  +      
Sbjct: 1626 KVDLLINVSDSINTNYTTG-GYMMRRAFVDAKISLITTTKLATLVIDAMLYRKSRLSKGK 1684

Query: 138  --ILIPDYQRYLAD 149
              I I  +Q YL++
Sbjct: 1685 DFIHIKSHQEYLSE 1698


>UniRef50_B2KDJ0 Carbamoyl-phosphate synthase, large subunit n=10 Tax=Bacteria
            RepID=B2KDJ0_ELUMP
          Length = 1102

 Score = 71.0 bits (173), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 24/135 (17%), Positives = 49/135 (36%), Gaps = 7/135 (5%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            ME T   +P +  +     +  K   M  ++          +YAT  T N +    G + 
Sbjct: 965  MESTHIKMPKKGILLSTGREKDKIKFMEVIDNVYKF--GLPVYATLGTANYLKEH-GYDA 1021

Query: 61   NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNV 120
              ++      D +   +I + K+D ++     L     + +  A+ + A   N  + TN+
Sbjct: 1022 IPVMYHH---DPKPVDVIKQRKVDFVVNVHKSLELDELEHN-SAIRKTAVKSNCSLLTNL 1077

Query: 121  ATADFIIQSPHFNDA 135
              A    ++     A
Sbjct: 1078 EKAIAYFKAFDSYKA 1092


>UniRef50_C4QQ90 Aspartate carbamoyltransferase (Carbamoyl-phosphate synthetase
           (Glutamine-hydrolysing)) (Dihydroorotase)
           (Dihydro-orotase (M38 family)) n=1 Tax=Schistosoma
           mansoni RepID=C4QQ90_SCHMA
          Length = 1370

 Score = 68.0 bits (165), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 22/162 (13%), Positives = 49/162 (30%), Gaps = 31/162 (19%)

Query: 8   LPARK-HIALVA-HDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLS 65
           LP    ++ L       K  ++  V++   L   + LY +  T +   +  G+++  +  
Sbjct: 405 LPKPGDNVFLSIGSYRHKLEMLPSVKQLHQL--GYKLYGSCGTADFY-QTQGISIIPVEW 461

Query: 66  GPMGGDQQVGA------------------LISEGKIDVLIFFWDPLNAVPHD------PD 101
                D  +                     + +    +++     L  V           
Sbjct: 462 PYEESDICISDNKIQNNMDASSKDGTIQQYLKDKLFSLIVSLS--LKKVGSRRLSAFVTR 519

Query: 102 VKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDY 143
                RLA   N+P+ T+V  A  +I++ +            
Sbjct: 520 GYQTRRLAVDTNVPLLTDVKLAKLLIEALYRYFHGQSANKTL 561


>UniRef50_UPI0001BCC751 carbamoyl phosphate synthase large subunit n=1 Tax=Campylobacter
           fetus subsp. venerealis str. Azul-94 RepID=UPI0001BCC751
          Length = 104

 Score = 67.2 bits (163), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 16/99 (16%), Positives = 34/99 (34%), Gaps = 5/99 (5%)

Query: 50  NLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLA 109
            +I +   +    +     G    +   +  G++ + +   D         D   + +  
Sbjct: 10  RIILKDAAIECEMVYKISEG-RPNIEDKLKNGEVSLAVNTSD---NKSSSSDAHKIRQAV 65

Query: 110 TVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLA 148
             + IP  TN+  A    +S   N+A  + +   Q YL 
Sbjct: 66  LRFKIPYFTNMNAALVAAKSISANEAA-LEVKSLQEYLE 103


>UniRef50_B7PNL6 Carbamoyl-phosphate synthase large chain, putative (Fragment) n=1
           Tax=Ixodes scapularis RepID=B7PNL6_IXOSC
          Length = 1136

 Score = 66.8 bits (162), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 20/142 (14%), Positives = 46/142 (32%), Gaps = 29/142 (20%)

Query: 1   MELTTRTLPARKHIALVAHDHC-KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMN 59
           +  T   +P +K+I L    +  K   +  V   + +   + LY +  T +      G+ 
Sbjct: 253 LVSTGFCIP-KKNIFLSIGSYKHKAEFLPSVRTLEKM--GYKLYGSLGTSDFYMEH-GIK 308

Query: 60  VNAMLS----------------GPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHD---- 99
           + AM                     G    +   + +   D+++    P+ +        
Sbjct: 309 IEAMTWPFHDAGEEGNANSSNVSSDGQSCSIADFLEQKGFDLVVNL--PMCSSGARRIST 366

Query: 100 --PDVKALLRLATVWNIPVATN 119
                    R+A  + +P+ T+
Sbjct: 367 VLTQGYRTRRMAVDYAVPLVTD 388


>UniRef50_A7T4N0 Predicted protein (Fragment) n=1 Tax=Nematostella vectensis
           RepID=A7T4N0_NEMVE
          Length = 1362

 Score = 62.6 bits (151), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 21/116 (18%), Positives = 39/116 (33%), Gaps = 32/116 (27%)

Query: 23  KQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGK 82
           K  L+  V   + L   + LYA+  T +  +   G+                        
Sbjct: 789 KNELLPSVHTLRNL--GYSLYASVGTADFYTEH-GIT---------------------NM 824

Query: 83  IDVLIFFWDPLNAVPHD------PDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
           ID+ I    PL + P               R+A  +++P+ T+V  A   +++   
Sbjct: 825 IDLFINL--PLRSNPGKKVSSFMTRGYQTRRMAIDYSVPLITDVKCAKLFVEALKR 878


>UniRef50_A7ZBN9 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Campylobacter
           concisus 13826 RepID=A7ZBN9_CAMC1
          Length = 90

 Score = 62.2 bits (150), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 17/94 (18%), Positives = 31/94 (32%), Gaps = 5/94 (5%)

Query: 58  MNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVA 117
           M    +     G    V   +  G I ++I   D         D K + +    + IP  
Sbjct: 1   MEAEFVYKISEG-RPNVEDRLKNGDIALVINTSDT---KSSVDDGKKIRQNVLRFKIPYF 56

Query: 118 TNVATADFIIQSPHFND-AVDILIPDYQRYLADR 150
           T +  A    +S         + +   Q YL+++
Sbjct: 57  TTIRAALAAAKSLSTVQTGKALEVKSLQEYLSEK 90


>UniRef50_Q1NYU0 Carbamoyl-phosphate synthase large subunit (Fragment) n=1
           Tax=Candidatus Sulcia muelleri str. Hc (Homalodisca
           coagulata) RepID=Q1NYU0_9FLAO
          Length = 168

 Score = 59.1 bits (142), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 21/139 (15%), Positives = 54/139 (38%), Gaps = 18/139 (12%)

Query: 1   MELTTRTLPARKHIALVAHDHCKQM-LMSWVERHQPLLEQHVLYATGTTGNLISRATGMN 59
           M      +P +K+I +  +    +  ++++++    ++  +++++   T N       + 
Sbjct: 37  MLSVGYNIP-KKNIFIYINSIKNRKIMLNYIKLL--IINNYIIFSKNGTYNFFIEN-NIL 92

Query: 60  VNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATN 119
              +       D  +   +   KID++I          ++ +   + R A  +NIP+ TN
Sbjct: 93  CKNID------DTNLIDNLK--KIDLIINI-----TYKNNKNDYLIRRAAIDFNIPLLTN 139

Query: 120 VATADFIIQSPHFNDAVDI 138
           +  A   I S     +   
Sbjct: 140 ICLAKVFIISFCEIKSFKR 158


>UniRef50_D2RG70 MGS domain protein n=1 Tax=Archaeoglobus profundus DSM 5631
           RepID=D2RG70_ARCPR
          Length = 155

 Score = 58.7 bits (141), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 20/132 (15%), Positives = 39/132 (29%), Gaps = 16/132 (12%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSG---PM 68
            ++ +      K     + +    L   + LYAT  T   +    G+ V  +        
Sbjct: 1   MNVLISVSRKDKLE--RFAKALVNL--GYTLYATEGTAKFL-ENCGIPVRRLSEITHLSE 55

Query: 69  GGD-----QQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
             D      +V   I  G   +++     L     D    AL+R      +PV       
Sbjct: 56  SEDLKTLHPEVFKRIYGGFFSLIVV---NLYEDKVDVGGVALIRAGIKAGVPVVCYPEDY 112

Query: 124 DFIIQSPHFNDA 135
           + +++       
Sbjct: 113 EKVLEDLKNGRD 124


>UniRef50_A4H8I3 Carbamoyl-phosphate synthase, putative n=17 Tax=cellular organisms
            RepID=A4H8I3_LEIBR
          Length = 1867

 Score = 57.9 bits (139), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 30/169 (17%), Positives = 57/169 (33%), Gaps = 29/169 (17%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M      +P +        D   ++L  +++R   +     +Y T  T N++    G+  
Sbjct: 1320 MLCQNFKIPEKGIFFSSDVDSQTEVLCPYIQRL--VRRGLKVYCTANTANVLQE-YGILC 1376

Query: 61   NAMLS---GPMGG----------DQQVGALISEGKIDVLIFFWDPL--------NAVPHD 99
              +L     P G           D++V     + K D++I   D                
Sbjct: 1377 EVLLQRSELPSGDASDSRCLAVYDEEVA---KKEKFDLVIQIRDKKRDFVLRRCTRETAS 1433

Query: 100  PDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLA 148
            PD   + RLA  +NIP+ T  +      +         + I  ++ Y+ 
Sbjct: 1434 PD-YWVRRLAVDYNIPLLTEPSIVKMFCECMD-LPPSSLEIEPFRHYVP 1480


>UniRef50_B4NUJ8 Rudimentary n=4 Tax=Diptera RepID=B4NUJ8_DROSI
          Length = 866

 Score = 57.2 bits (137), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 13/76 (17%), Positives = 29/76 (38%), Gaps = 8/76 (10%)

Query: 69  GGDQQVGALISEGKIDVLIFFWDPLNAVPHD------PDVKALLRLATVWNIPVATNVAT 122
           G  + +   ++  + D++I    P++                  RLA  ++IP+ T+V  
Sbjct: 26  GELRHLAEFLANKQFDLVINL--PMSGGGARRVSSFMTHGYRTRRLAVDYSIPLVTDVKC 83

Query: 123 ADFIIQSPHFNDAVDI 138
              +++S   N     
Sbjct: 84  TKLLVESMRMNGGKPP 99


>UniRef50_B4R614 GD17297 n=1 Tax=Drosophila simulans RepID=B4R614_DROSI
          Length = 1233

 Score = 56.0 bits (134), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 14/65 (21%), Positives = 27/65 (41%), Gaps = 3/65 (4%)

Query: 1    MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNV 60
            M  T   +P    +  +     K  L+  +     +   + LYA+  TG+  +   G+NV
Sbjct: 1170 MMSTGFQIPKNAVLLSIGSFKHKMELLPSIRDLAKM--GYKLYASMGTGDFYAEH-GVNV 1226

Query: 61   NAMLS 65
            +  +S
Sbjct: 1227 SIFMS 1231


>UniRef50_B8BWS2 Predicted protein n=1 Tax=Thalassiosira pseudonana RepID=B8BWS2_THAPS
          Length = 1354

 Score = 55.6 bits (133), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 15/76 (19%)

Query: 4    TTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
            +       + +ALVAH+H +  +  ++E +  +L++  +  T T                
Sbjct: 1266 SKFAPSDMRQLALVAHNHMRPAMKDFIEMYFSILKKFRITGTQT---------------K 1310

Query: 64   LSGPMGGDQQVGALIS 79
            +SGP+GGD QV AL+ 
Sbjct: 1311 ISGPLGGDAQVAALMC 1326


>UniRef50_Q64E58 Carbamoyl-phosphate synthase large chain n=1 Tax=uncultured
           archaeon GZfos14B8 RepID=Q64E58_9ARCH
          Length = 69

 Score = 54.1 bits (129), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 9/72 (12%), Positives = 20/72 (27%), Gaps = 3/72 (4%)

Query: 77  LISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAV 136
           ++   +I + +   +         D   + R      IP  T +  A     +       
Sbjct: 1   MMHSQEIKLAV---NTPTDKQSYKDGYQIRRACIELGIPYITTMQAAKAAASAILGMKGS 57

Query: 137 DILIPDYQRYLA 148
           +I +     Y  
Sbjct: 58  EIEVKSLNEYFK 69


>UniRef50_D2MK92 Carbamoyl phosphate synthetase large subunit (Fragment) n=1
           Tax=Candidatus Poribacteria sp. WGA-A3
           RepID=D2MK92_9BACT
          Length = 76

 Score = 51.0 bits (121), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 12/77 (15%), Positives = 29/77 (37%), Gaps = 3/77 (3%)

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS 129
           G   +   I    +D++I   +      H  +   + ++A   +IP+ + +  A   + +
Sbjct: 1   GRPTIHDYIKNHAVDLII---NTPTGDIHRTNELLIRQMAIEHDIPIFSTIPGAAAAVNA 57

Query: 130 PHFNDAVDILIPDYQRY 146
                  +I +   Q Y
Sbjct: 58  IDALQRGEISVSPLQDY 74


>UniRef50_C2KIY6 Possible aspartate carbamoyltransferase catalytic subunit n=1
           Tax=Leuconostoc mesenteroides subsp. cremoris ATCC 19254
           RepID=C2KIY6_LEUMC
          Length = 187

 Score = 50.2 bits (119), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 9/61 (14%), Positives = 21/61 (34%), Gaps = 2/61 (3%)

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHF 132
              A + + K+ V+I           + D + +   A    +P+ T + T    ++    
Sbjct: 121 NAVAALRQQKVQVVIN--TTQADDRAESDGRLIRNAAIENAVPLFTALDTVSAFLEVLES 178

Query: 133 N 133
            
Sbjct: 179 R 179


>UniRef50_D1B6T5 Carbamoyl-phosphate synthase, large subunit n=1 Tax=Thermanaerovibrio
            acidaminovorans DSM 6589 RepID=D1B6T5_THEAS
          Length = 1049

 Score = 48.7 bits (115), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 18/97 (18%), Positives = 32/97 (32%), Gaps = 11/97 (11%)

Query: 39   QHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPH 98
               +Y T  T   + R  G+    +   P+ G   +G  +  G++  ++    PL    +
Sbjct: 958  GCPIYGTPGTCGRLVR-VGVPCRRVD--PLEG---IG--MVGGEVGWVVNTRSPLEDRGY 1009

Query: 99   DPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDA 135
                  L R A        T V T   + Q+      
Sbjct: 1010 ---GFELRRRAAEVGALCVTRVDTLVGLAQALSLGRG 1043


>UniRef50_B6JVJ9 Carbamoyl-phosphate synthase arginine-specific large chain n=1
            Tax=Schizosaccharomyces japonicus yFS275
            RepID=B6JVJ9_SCHJY
          Length = 1125

 Score = 47.9 bits (113), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 18/149 (12%), Positives = 45/149 (30%), Gaps = 14/149 (9%)

Query: 5    TRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATG-MNVNAM 63
               +P   H  L+  D     L     +   L   + LY        + +    + V  +
Sbjct: 979  NFKVPLPGHGVLLGGDRK--ELADVAAKLHEL--GYKLYVAE---KALHKKLAPVPVTVI 1031

Query: 64   LSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATA 123
                      + A+  +  I  +            +     + R A  +N+ +  +V  A
Sbjct: 1032 DFPKEKR--ALRAVFEKNDIQAVFNLASG-RGKSTEDQDYIMRRNAVDFNVTLFNDVRCA 1088

Query: 124  DFIIQSPHFNDAVDILIPDYQRYLADRLK 152
            +  ++          L+   ++ + + +K
Sbjct: 1089 ELFVECL---KEKLPLVLSEEKTMPNEVK 1114


>UniRef50_O28464 Inosine monophosphate cyclohydrolase n=1 Tax=Archaeoglobus fulgidus
           RepID=O28464_ARCFU
          Length = 157

 Score = 46.0 bits (108), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 18/141 (12%), Positives = 48/141 (34%), Gaps = 23/141 (16%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA----------TGM-NV 60
             + +      K+ +    +R   +   + + AT  T + +             TG+   
Sbjct: 1   MKVLIS--SSVKEGIECLAKRLAEM--GYEILATEGTADYLQEKGVNALKLSEITGIAES 56

Query: 61  NAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKA----LLRLATVWNIPV 116
            ++ +       ++  +I  G+I  ++     L   P   ++      LLR A    +P 
Sbjct: 57  KSIKTLH----PKIYEMIFSGEIKAVVVIPYNLRENPCRENIDIGGISLLRAAAKAGVPA 112

Query: 117 ATNVATADFIIQSPHFNDAVD 137
           A ++ +   +++        +
Sbjct: 113 AYDLKSFQKLVEVLEGKKRYN 133


>UniRef50_A2BJL3 Carbamoyl-phosphate synthase large chain n=13 Tax=Archaea
            RepID=CARB_HYPBU
          Length = 1073

 Score = 45.6 bits (107), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 21/144 (14%), Positives = 46/144 (31%), Gaps = 23/144 (15%)

Query: 5    TRTLPARKHIALVAHDHCK--QMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNA 62
               +P    I L+     +    L    +      + + +Y             GM V+ 
Sbjct: 943  GNRIPPAGSIVLIYTPTGRGSSDLSQAAKLMTE--KGYTVYTIE----------GMEVDG 990

Query: 63   MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
                P+   +Q   L+  G + +L+             D   + RLA    +PV  +   
Sbjct: 991  AEPLPL---EQALRLVRMGGVGLLM-----TTDYAPQRD-YRVRRLAVDLGVPVVLDARL 1041

Query: 123  ADFIIQSPHFNDAVDILIPDYQRY 146
            A  + ++ +     ++   + + Y
Sbjct: 1042 ARMLAEAINRVGLENLEALELREY 1065


>UniRef50_B9L973 Bifunctional purine biosynthesis protein PurH n=9
           Tax=Epsilonproteobacteria RepID=B9L973_NAUPA
          Length = 504

 Score = 43.7 bits (102), Expect = 0.002,   Method: Composition-based stats.
 Identities = 19/169 (11%), Positives = 47/169 (27%), Gaps = 41/169 (24%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRAT--GMNVNAMLSGPM- 68
               L   D  K  ++ + ++   L     + +TG T  ++       ++++ +   P  
Sbjct: 1   MRALLSVSD--KTGIVDFAKQLVDL--GFEIISTGGTKRILQENGIDAIDISEITKFPEC 56

Query: 69  --------------------GGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVK----- 103
                               G D +    +   +ID++     P        D       
Sbjct: 57  FGGRVKTLNPYVHGGILYRSGIDDEEAEKLGITRIDLVAVNLYPFKETIERTDDFDEIIE 116

Query: 104 -------ALLRLATVW--NIPVATNVATADFIIQSPHFNDAVDILIPDY 143
                   ++R A     ++ + T+    D ++ +            D 
Sbjct: 117 NIDIGGPTMVRSAAKNFKDVLIVTDPEDYDTVVNALKEKKDTYEFRRDL 165


>UniRef50_D1B2Y6 Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP
           cyclohydrolase n=5 Tax=Campylobacterales
           RepID=D1B2Y6_SULD5
          Length = 510

 Score = 42.9 bits (100), Expect = 0.003,   Method: Composition-based stats.
 Identities = 14/107 (13%), Positives = 35/107 (32%), Gaps = 21/107 (19%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRA--TGMNVNAMLSGPMG 69
               +   D  K  ++ +      L     + +TG T  L+     + + ++ +   P  
Sbjct: 1   MRALISVSD--KTGIVEFARDLVEL--GFEVISTGGTYKLLKEEGISALEISEVTKFPE- 55

Query: 70  GDQQVGALISEGKIDVLIFFWDPLNAVP--HDPDVKALLRLATVWNI 114
                   + +G++       +P+      H  D+   ++ A    I
Sbjct: 56  --------MFDGRVK----TLNPMIHGGILHRRDLPLHVKTAQEHGI 90


>UniRef50_A7HM64 IMP cyclohydrolase n=2 Tax=Thermotogaceae RepID=A7HM64_FERNB
          Length = 429

 Score = 42.5 bits (99), Expect = 0.004,   Method: Composition-based stats.
 Identities = 12/53 (22%), Positives = 21/53 (39%), Gaps = 5/53 (9%)

Query: 12 KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML 64
          K   +   D  K  L+ + +          + +TG T  L+S A G+ V  + 
Sbjct: 4  KRALISVSD--KAGLVEFAKNLVD--RGVEIISTGGTAKLLSDA-GIPVKQVS 51


>UniRef50_A8WNQ4 C. briggsae CBR-PYR-1 protein n=2 Tax=Caenorhabditis briggsae
            RepID=A8WNQ4_CAEBR
          Length = 2090

 Score = 41.8 bits (97), Expect = 0.007,   Method: Composition-based stats.
 Identities = 18/103 (17%), Positives = 35/103 (33%), Gaps = 15/103 (14%)

Query: 1    MELTTRTLPARKHIALVAHD-HCKQMLMSWVERHQPLLEQHVLYATGTTGNLI---SRAT 56
            +  T   +P +++I +     H K  ++  VE  Q L     LY +  T   +       
Sbjct: 1274 LLSTGFVVP-KRNIFISIGGYHAKAEMLKSVETLQKL--GFDLYGSKGTALAMVGRRPTM 1330

Query: 57   GMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHD 99
               V+ + S  +            G +D+ +   +P      D
Sbjct: 1331 NSLVDCVTSKSLKRLP--------GMVDIHVHVREPGATHKED 1365


>UniRef50_A1VZU4 IMP cyclohydrolase n=25 Tax=Epsilonproteobacteria
          RepID=PUR9_CAMJJ
          Length = 510

 Score = 41.8 bits (97), Expect = 0.007,   Method: Composition-based stats.
 Identities = 10/53 (18%), Positives = 21/53 (39%), Gaps = 5/53 (9%)

Query: 12 KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML 64
              L   D  K+ ++ + +  + L     + +TG T  L+    G+ V  + 
Sbjct: 1  MRALLSVSD--KEGIVEFGKELENL--GFEILSTGGTFKLLKEN-GIKVIEVS 48


>UniRef50_UPI000169A620 carbamoyl-phosphate synthase, large subunit n=1 Tax=Yersinia pestis
           FV-1 RepID=UPI000169A620
          Length = 75

 Score = 41.4 bits (96), Expect = 0.010,   Method: Composition-based stats.
 Identities = 7/61 (11%), Positives = 20/61 (32%), Gaps = 3/61 (4%)

Query: 78  ISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVD 137
           I  G+   ++   +  +      D K + R A  + +   T +        + + +    
Sbjct: 3   IKNGEYTYIV---NTTSGRQAIEDSKLIRRSALQYKVHYDTTLNGGFATAMALNADPTDQ 59

Query: 138 I 138
           +
Sbjct: 60  V 60


>UniRef50_B9KZE8 Bifunctional purine biosynthesis protein PurH n=1
          Tax=Thermomicrobium roseum DSM 5159 RepID=B9KZE8_THERP
          Length = 504

 Score = 41.4 bits (96), Expect = 0.010,   Method: Composition-based stats.
 Identities = 11/53 (20%), Positives = 19/53 (35%), Gaps = 5/53 (9%)

Query: 12 KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML 64
              L   D  K  +  + +R   L     ++ATG T   +    G+ V  + 
Sbjct: 1  MRALLSVAD--KTGITVFAQRLVDL--GWEIFATGGTARELREH-GLPVREIS 48


>UniRef50_C5CL84 IMP cyclohydrolase n=10 Tax=Bacteria RepID=PUR9_VARPS
          Length = 535

 Score = 41.0 bits (95), Expect = 0.012,   Method: Composition-based stats.
 Identities = 11/51 (21%), Positives = 21/51 (41%), Gaps = 5/51 (9%)

Query: 13 HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAM 63
             +   D  K  ++ + +    L     L +TG T  L++ A G+ V  +
Sbjct: 4  TALISVSD--KTGILEFAQALHAL--GIKLLSTGGTAKLLADA-GLPVTEV 49


>UniRef50_Q27448 Glutamine-dependent carbamoyl phosphate synthase n=3 Tax=cellular
            organisms RepID=Q27448_BABBO
          Length = 1645

 Score = 41.0 bits (95), Expect = 0.012,   Method: Composition-based stats.
 Identities = 14/117 (11%), Positives = 27/117 (23%), Gaps = 19/117 (16%)

Query: 50   NLISRATGMNVNAMLSGPMGGD------------QQVGALISEGKIDVLIFFWDPLNAVP 97
                   G ++  + S    G              +   L+    + + I          
Sbjct: 1530 QFFEDTIGDSLLHVGSSHKCGRLLCCTNLVRKVSPRPVELMKSVVVHMFINAAGCAIPN- 1588

Query: 98   HDPDVKALLRLATVWNIPVATNVATADFIIQSPH------FNDAVDILIPDYQRYLA 148
               D   + R A    + + T +  A   I +            +       Q YL 
Sbjct: 1589 RLSDGYVMRRAAVDNKVTLITCMKLAKLFIDALVMRHIRTSKGKLFFHNKSQQEYLN 1645


>UniRef50_B7J5P7 IMP cyclohydrolase n=12 Tax=Bacteria RepID=PUR9_ACIF2
          Length = 524

 Score = 41.0 bits (95), Expect = 0.013,   Method: Composition-based stats.
 Identities = 24/133 (18%), Positives = 45/133 (33%), Gaps = 36/133 (27%)

Query: 13  HIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQ 72
              +   D  K+ ++ +  R Q       + +TG T   +  A G+ V  +      GD 
Sbjct: 9   RALISVSD--KRGVVEFARRLQDF--GVEILSTGGTAKALM-ADGVAVQEV------GDY 57

Query: 73  QVGALISEGKIDVLIFFWDPLNAVPH------DPDVKALLRLATVWNI-----------P 115
                + EG++         L+   H        D     ++A  + I           P
Sbjct: 58  TGFPELLEGRLK-------TLHPKIHGGLLAKRDDSSHTRQMA-EYGIPAIDLLCVNLYP 109

Query: 116 VATNVATADFIIQ 128
            A  +A+AD  ++
Sbjct: 110 FAETIASADCTLE 122


>UniRef50_O94313 Carbamoyl-phosphate synthase arginine-specific large chain n=30
            Tax=Dikarya RepID=CARB_SCHPO
          Length = 1160

 Score = 40.6 bits (94), Expect = 0.014,   Method: Composition-based stats.
 Identities = 20/139 (14%), Positives = 40/139 (28%), Gaps = 12/139 (8%)

Query: 5    TRTLPARKH-IALVAHDHCKQMLMSWVERHQPLLEQHVLY-ATGTTGNLISRATGMNVNA 62
               +P     I L      +  L         L   + LY A      L+          
Sbjct: 1013 NFKIPLPGQGILL---GGDRPELAGIAADLSKL--GYKLYVANKDAAKLLQP----TSAE 1063

Query: 63   MLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVAT 122
            ++  P+   + + A+  +  I  +            D D   + R A  +N+ +  +V  
Sbjct: 1064 VVEFPVKDKRALRAIFEKYNIRSVFNLASARGKNVLDQD-YVMRRNAVDFNVTLINDVNC 1122

Query: 123  ADFIIQSPHFNDAVDILIP 141
            A   ++S        +   
Sbjct: 1123 AKLFVESLKEKLPSVLSEK 1141


>UniRef50_Q9X0X6 IMP cyclohydrolase n=9 Tax=Thermotogaceae RepID=PUR9_THEMA
          Length = 452

 Score = 40.6 bits (94), Expect = 0.014,   Method: Composition-based stats.
 Identities = 25/132 (18%), Positives = 47/132 (35%), Gaps = 21/132 (15%)

Query: 11  RKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP--- 67
            K I +    + K+  +  +       +   ++A+  T   +    G+  N + +     
Sbjct: 1   MKRILVSL--YEKEKYLDILRELHE--KGWEIWASSGTAKFLKSN-GIEANDVSTITGFE 55

Query: 68  --MGG-----DQQVGALIS--EGKIDVLIFFWDPLNAVPHDPDVKALLRLATVW--NIPV 116
             +GG       ++ A I   E + DV+  F D       D    ALLR A      +  
Sbjct: 56  NLLGGLVKTLHPEIFAGILGPEPRWDVV--FVDLYPPPDIDIGGVALLRAAAKNWKKVKP 113

Query: 117 ATNVATADFIIQ 128
           A ++ T    I+
Sbjct: 114 AFDMETLKLAIE 125


>UniRef50_B0UWT1 IMP cyclohydrolase n=50 Tax=Gammaproteobacteria RepID=PUR9_HAES2
          Length = 532

 Score = 40.6 bits (94), Expect = 0.016,   Method: Composition-based stats.
 Identities = 18/114 (15%), Positives = 35/114 (30%), Gaps = 29/114 (25%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAML------- 64
           +   L   D  K  ++ + +    +     L +TG T  L++   G+ V  +        
Sbjct: 8   RQALLSVSD--KSGIVEFAQGL--VRRGVKLLSTGGTAKLLAEN-GIPVTEVSDYTGFPE 62

Query: 65  -----------SGPMG--GDQQVGALISEGK----IDVLIFFWDPLNAVPHDPD 101
                          G  G + +   +        ID+++    P  A    PD
Sbjct: 63  MMEGRVKTLHPKIHGGILGRRGIDDEVMMQHQIDAIDMVVVNLYPFAATVAKPD 116


>UniRef50_Q96CK3 CAD protein (Fragment) n=3 Tax=Euarchontoglires RepID=Q96CK3_HUMAN
          Length = 851

 Score = 40.2 bits (93), Expect = 0.019,   Method: Composition-based stats.
 Identities = 6/69 (8%), Positives = 21/69 (30%), Gaps = 4/69 (5%)

Query: 74  VGALISEGKIDVLIFFWDPLNAVPHDPD----VKALLRLATVWNIPVATNVATADFIIQS 129
           +   ++E   +++I                       RLA  +++P+  ++      +++
Sbjct: 6   ILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEA 65

Query: 130 PHFNDAVDI 138
                    
Sbjct: 66  LGQIGPAPP 74


>UniRef50_C3KX73 Carbamoyl-phosphate synthase large chain n=1 Tax=Clostridium
           botulinum Ba4 str. 657 RepID=C3KX73_CLOB6
          Length = 59

 Score = 40.2 bits (93), Expect = 0.021,   Method: Composition-based stats.
 Identities = 9/40 (22%), Positives = 14/40 (35%)

Query: 89  FWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQ 128
              P        D   + R A   N+ V T++ T   I+ 
Sbjct: 2   VNTPTKGNDSKRDGFHIRRAAIERNLGVITSLDTLKAIVD 41


>UniRef50_B4EYT2 IMP cyclohydrolase n=36 Tax=Proteobacteria RepID=PUR9_PROMH
          Length = 529

 Score = 39.5 bits (91), Expect = 0.031,   Method: Composition-based stats.
 Identities = 20/119 (16%), Positives = 34/119 (28%), Gaps = 29/119 (24%)

Query: 7   TLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLS- 65
            L   +   L   D  K  ++ + +          L +TG T  L++ A G+ V  +   
Sbjct: 3   HLRPIRRALLSVSD--KAGILEFAKALVE--RNVELLSTGGTARLLAEA-GLPVIEVSDY 57

Query: 66  -----------------------GPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPD 101
                                  G  G D  +        ID+++    P       PD
Sbjct: 58  TGFPEMMDGRVKTLHPKVHGGILGRRGQDDTIMEEHDIRPIDMVVVNLYPFAKTVAHPD 116


>UniRef50_D1VVH5 Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP
           cyclohydrolase n=1 Tax=Peptoniphilus lacrimalis 315-B
           RepID=D1VVH5_9FIRM
          Length = 501

 Score = 39.5 bits (91), Expect = 0.035,   Method: Composition-based stats.
 Identities = 11/96 (11%), Positives = 29/96 (30%), Gaps = 8/96 (8%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGD 71
               +    + K+ ++ +      L     + +TG T  ++     + V  +     G  
Sbjct: 1   MRALISV--YDKENIVEFARELVALD--WEIISTGGTFKILKEN-NIPVKEVEEVT-GQR 54

Query: 72  QQVGALIS--EGKIDVLIFFWDPLNAVPHDPDVKAL 105
           + +   +     KI   I F           + + +
Sbjct: 55  EILSGRVKTLHPKIHGGILFRRDNKDDKKTIEEEQI 90


>UniRef50_D1JEE9 Putative uncharacterized protein n=1 Tax=uncultured archaeon
           RepID=D1JEE9_9ARCH
          Length = 169

 Score = 38.7 bits (89), Expect = 0.056,   Method: Composition-based stats.
 Identities = 25/150 (16%), Positives = 50/150 (33%), Gaps = 27/150 (18%)

Query: 12  KHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGP---- 67
               +  ++  K +++ +            + AT  T  LI    G+ V  + +      
Sbjct: 1   MKALISVYN--KDIVVEFARALNE--RGLEIIATEGTARLILDN-GIPVTKVSAFTGVQE 55

Query: 68  -MGG-----DQQVGALISEGKIDVL--------IFFWDPLNAVPHDPDVKALLRLATVW- 112
            +GG        + A I+ G I+++        I   + L+ +  D    A+LR      
Sbjct: 56  MLGGKLKTLHPTIHAGIATGAIEIVTVNLIPLDISSENTLDNM--DLGGVAMLRSGIKNF 113

Query: 113 -NIPVATNVATADFIIQSPHFNDAVDILIP 141
            ++ V  N A    II+       +     
Sbjct: 114 EHVAVIVNPARYKGIIEELRIKGEIARDTK 143


>UniRef50_UPI0000384730 COG0313: Predicted methyltransferases n=1 Tax=Magnetospirillum
           magnetotacticum MS-1 RepID=UPI0000384730
          Length = 298

 Score = 38.7 bits (89), Expect = 0.065,   Method: Composition-based stats.
 Identities = 14/61 (22%), Positives = 25/61 (40%), Gaps = 4/61 (6%)

Query: 71  DQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSP 130
              + A +  G++  L+   D    +  DP    L+R     NIPV T +  A  ++ + 
Sbjct: 84  RPALLARLGRGEVVALV--SDAGTPMVSDP-GFKLVRDCIESNIPV-TALPGASAVLTAL 139

Query: 131 H 131
            
Sbjct: 140 Q 140


  Database: uniref50.fasta
    Posted date:  Mar 8, 2010 10:38 AM
  Number of letters in database: 1,040,396,356
  Number of sequences in database:  3,077,464
  
Lambda     K      H
   0.312    0.154    0.408 

Lambda     K      H
   0.267   0.0474    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 998,727,479
Number of Sequences: 3077464
Number of extensions: 45531661
Number of successful extensions: 116052
Number of sequences better than 1.0e-01: 163
Number of HSP's better than  0.1 without gapping: 247
Number of HSP's successfully gapped in prelim test: 119
Number of HSP's that attempted gapping in prelim test: 115383
Number of HSP's gapped (non-prelim): 383
length of query: 152
length of database: 1,040,396,356
effective HSP length: 115
effective length of query: 37
effective length of database: 686,487,996
effective search space: 25400055852
effective search space used: 25400055852
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 87 (37.9 bits)
